PharMolix/UniProtQA huggingface dataset:
Protein: UB2G2_BOVIN
Sequence: MAGTALKRLMAEYKQLTLNPPEGIVAGPMNEENFFEWEALIMGPEDTCFEFGVFPAILSFPLDYPLSPPKMRFTCEMFHPNIYPDGRVCISILHAPGDDPMGYESSAERWSPVQSVEKILLSVVSMLAEPNDESGANVDASKMWRDDREQFYKVAKQIVQKSLGL
What is the function of this protein?
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.  In vitro catalyzes 'Lys-48'-linked polyubiquitination.  Involved in endoplasmic reticulum-associated degradation (ERAD).  Required for sterol-induced ubiquitination of 3-hydroxy-3-methylglutaryl coenzyme A reductase and its subsequent proteasomal degradation.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 G2, E2 ubiquitin-conjugating enzyme G2, Ubiquitin carrier protein G2, Ubiquitin-protein ligase G2.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Lipid droplet.
Protein: GCAT_AERHY
Sequence: MKKWFVCLLGLVALTVQAADSRPAFSRIVMFGDSLSDTGKMYSKMRGYLPSSPPYYEGRFSNGPVWLEQLTNEFPGLTIANEAEGGPTAVAYNKISWNPKYQVINNLDYEVTQFLQKDSFKPDDLVILWVGANDYLAYGWNTEQDAKRVRDAISDAANRMVLNGAKEILLFNLPDLGQNPSARSQKVVEAASHVSAYHNQLLLNLARQLAPTGMVKLFEIDKQFAEMLRDPQNFGLSDTENACYGGSYVWKPFASRSASTDSQLSAFNPQERLAIAGNPLLAQAVASPMAARSASTLNCEGKMFWDQVHPTTVVHAALSEPAATFIESQYEFLAH
What is the function of this protein?
Fatty acid transfer between phosphatidylcholine and cholesterol.
What are the official names of this protein?
Phosphatidylcholine-sterol acyltransferase, Glycerophospholipid-cholesterol acyltransferase, GCAT.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family.
Protein: RS14_MYCS2
Sequence: MAKKSKIVKNEQRRELVQRYAERRAELKRTIRDPASSPERRAAAVSALQRLPRDSSPVRLRNRDVVDGRPRGHLRKFGLSRVRVREMAHRGELPGVRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: 3MGH_FRATH
Sequence: MNNLEAILRLKTIDAAKKLLGHFLVSKYNNKILIGKIVETEAYLYNDPACHSYSNRTKRNSMMYAQAGTSYVYFTYGMHYCFNVVTADVGIGEAILIRALEPIAGIEQMQLNRSKTKLIDLCSGPAKLTQALNINLKDNGINLLDKDSSILLRYNNDLINEIDIVQTQRIGISKAKDMPYRFYIKDNIFVSKK
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: UREF_CHRSD
Sequence: MSTEPVSQHDPLALAGLMQLVSPALPIGAFAWSQGLESALELGWVDDEASLGEWLAGVLDDGLTRCELPVLARVHRAWAEGDAQALAHWNDWLQANRETRELLEEEQRLGGTLVRLLRSLDQVPVTPAMPETPGYVVVFALAARVRGVSREDAMLGFAWAWLENQLTVACKALPLGQTSAQRLVERLRPALVAAVSEALALDDDDLGPALPGLALASALHETQYSRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO3_LACJO
Sequence: MLKSVIENVHALEIFDSRGNPTVEVFVTLSNGVVGKAEVPSGASTGENEAVELRDGGSRLGGKGVMNAVNNVNTEINDALKGLDPHDQPNIDATMIALDGTPNKGRLGANAILGVSMATAAAAAKDNHQPLYRYLGGTDLEMPQTFHNVINGGEHADNGIDIQEFMITPVAKTSFRDGFEKIVNVYHTLKKVLEDMGYETGLGDEGGFAPNMKNSEEALKALHESIIKAGYKPGEDIAIACDCAASYFYNKEDGKYHLEGKVLTDEELADYYDKLLDEFPELISMEDPYDENDVEGMVKFTQSHKDRIQIVLDDFICTNPKLLNKAIHEGAGNASLIKLNQIGTVTETLETIRLSRKNGYNTMISHRSGETGDTFIADFAVAVNGGQLKTGAPARSERVEKYNRLLEIEEELGKGERLAFFPDNVDLD
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase 3, 2-phospho-D-glycerate hydro-lyase 3, 2-phosphoglycerate dehydratase 3.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RU1C_BATDJ
Sequence: MTMDGVFPLTATVDYCDIFLTHDSASVRKAHNTGWKHKMQVEHYYNAEVDPAKIQSVIDNVTKAYIDAGLPGFPELIAVGVNGQRGQPVGGPPRPPQPFHNGGRPGPPGRPPMGMFPPQRPMMPPPHMRPGLSQMPPGMRPPGPPPHGFMNGSMPPPLGTPVMENGPVAGQQSQAPVAPRIHPDRLRLAGNSIKSKLVIESIYCFYPFGCLDSQIATHTFLYHCANDS
What is the function of this protein?
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome.  U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing.  The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA.  Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
What are the official names of this protein?
U1 small nuclear ribonucleoprotein C, U1 snRNP C, U1-C, U1C.
What is the protein family that this protein belongs to?
Belongs to the U1 small nuclear ribonucleoprotein C family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CLFB_STAAC
Sequence: MKKRIDYLSNKQNKYSIRRFTVGTTSVIVGATILFGIGNHQAQASEQSNDTTQSSKNNASADSEKNNMIETPQLNTTANDTSDISANTNSANVDSTTKPMSTQTSNTTTTEPASTNETPQPTAIKNQATAAKMQDQTVPQEANSQVDNKTTNDANSIATNSELKNSQTLDLPQSSPQTISNAQGTSKPSVRTRAVRSLAVAEPVVNAADAKGTNVNDKVTASNFKLEKTTFDPNQSGNTFMAANFTVTDKVKSGDYFTAKLPDSLTGNGDVDYSNSNNTMPIADIKSTNGDVVAKATYDILTKTYTFVFTDYVNNKENINGQFSLPLFTDRAKAPKSGTYDANINIADEMFNNKITYNYSSPIAGIDKPNGANISSQIIGVDTASGQNTYKQTVFVNPKQRVLGNTWVYIKGYQDKIEESSGKVSATDTKLRIFEVNDTSKLSDSYYADPNDSNLKEVTDQFKNRIYYEHPNVASIKFGDITKTYVVLVEGHYDNTGKNLKTQVIQENVDPVTNRDYSIFGWNNENVVRYGGGSADGDSAVNPKDPTPGPPVDPEPSPDPEPEPTPDPEPSPDPEPEPSPDPDPDSDSDSDSGSDSDSGSDSDSESDSDSDSDSDSDSDSDSESDSDSESDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSESDSDSESDSESDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSRVTPPNNEQKAPSNPKGEVNHSNKVSKQHKTDALPETGDKSENTNATLFGAMMALLGSLLLFRKRKQDHKEKA
What is the function of this protein?
Cell surface-associated protein implicated in virulence by promoting bacterial attachment to both alpha- and beta-chains of human fibrinogen and inducing the formation of bacterial clumps.
What are the official names of this protein?
Clumping factor B, Fibrinogen receptor B, Fibrinogen-binding protein B.
What is the protein family that this protein belongs to?
Belongs to the serine-aspartate repeat-containing protein (SDr) family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor. Note=Anchored to the cell wall by sortase A (By similarity).
Protein: RL13_MYCVP
Sequence: MSTYTPKAGDTTRTWYVIDATDVVLGRLAVEAAKLLRGKHKPTFTPNVDGGDFVIVINADKIALSGDKLNKKFAYRHSGYPGGLRKRSIGELLQKHPTRVVENAIVGMLPHNKLSRQVQKKLKVYAGPEHPHSAQQPVPFEIKQVAQ
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: PUR5_CERSK
Sequence: MAEQQKGLTYADAGVDIDAGNALVERIKPAAKRTARPGTVSGLGGFGALFDLKAAGYHDPVLVAATDGVGTKLRIAIDTGEVDTIGIDLVAMCVNDLVCQGAEPLFFLDYFATGKLEVAQAARIIEGIAEGCAASGCALIGGETAEMPGMYHKGDFDLAGFAVGAMERGADLPQGVAEGDVLLGLGSNGVHSNGYSFVRKVVELSGLGWDAPAPFGGDSLGRALLAPTRLYVKQALAAVRAGGVHALAHITGGGLTENLPRVLPEGLGARIDLSAWELPSVFRWLAETASMAEPELLKTFNCGIGMIVVVAADRADEIAALLAAEGETVTRIGEVIAGEGVSYDGRLL
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AZOR_ECO24
Sequence: MSKVLVLKSSILAGYSQSNQLSDYFVEQWREKHSADEITVRDLAANPIPVLDGELVGALRPSDAPLTPRQQEALALSDELIAELKAHDVIVIAAPMYNFNISTQLKNYFDLVARAGVTFRYTENGPEGLVTGKKAIVITSRGGIHKDGPTDLVTPYLSTFLGFIGITDVKFVFAEGIAYGPEMAAKAQSDAKAAIDSIVAA
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: FTHS_STRA3
Sequence: MKTDIEIAQSVALKPIAEIVEQVGIGFDDIELYGKYKAKLSFDKIEAVRSQKVGKLILVTAINPTPAGEGKSTMSIGLADALNKIGKKTMIALREPSLGPVMGIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELDIDQRRVIWKRVVDLNDRALRQVIVGLGSSVNGIPREDGFDITVASEIMAILCLATDLSDLKKRLSNIVVAYSRDRKPIYVKDLKIEGALTLILKDAIKPNLVQTIYGTPALVHGGPFANIAHGCNSVLATSTALRLADYVVTEAGFGADLGAEKFLDIKTPNLPTSPDAIVIVATLRALKMHGGVSKEDLSQENVKAVKRGFTNLERHVNNMRQYGVPVVVAINQFTADTESEIATLKTLCSNIDVAVELASVWEDGADGGLELAQTVANVIETQSSNYKRLYNDEDTIEEKIKKIVTKIYGGNKVHFGPKAQIQLKEFSDNGWDKMPICMAKTQYSFSDNPNLLGAPTDFDITVREFVPKTGAGFIVALTGDVLTMPGLPKKPAALNMDVLEDGTAIGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: RS4_COLP3
Sequence: MARYLGPKLKLSRREGTDLFLKSGVRAIDTKCKIETIPGQHGARRGRLSDYGVQLREKQKVRRIFGVLEKQFSNYYKEAARQKGNTGENLLQLLETRLDNVVYRMGYASTRAEARQLVSHKAIVVNGVVVNIPSFTVKAEDTVSVREKSKTQARIIAALELADQREKPLWVEVDTKKLEGVFKRVPDRADLSAEINEQLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RRF_MAGSA
Sequence: MSAPTNWNDLKKDITRRMDSAVEVLKKEFSGLRSGRASINLLDPVVVEAYGQTMPLSQCGTVGVPEPRMLTVQVWDKSQVKAVEKAIANAGLGLNPQADGQMIRVPIPPLNEERRKELQKVAGKYSEQARISVRNVRRDGMDTLKKMEKDGHISEDEIKKHEKEIQAITDETIKKIDEALGHKEKEIMQV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WFD18_MOUSE
Sequence: MKTATVFVLVALIFMTMTTAWALSNPKEKPGACPKPPPRSFGTCDERCTGDGSCSGNMKCCSNGCGHACKPPVF
What is the function of this protein?
Could have proteinase inhibiting capacity.
What are the official names of this protein?
WAP four-disulfide core domain protein 18, Extracellular peptidase inhibitor, Protein WDNM1.
What are the subcellular locations of this protein?
Secreted.
Protein: TNFL6_MACMU
Sequence: MQQPFNYPYPQIYWVDSSASSPWAPPGTVLPCPTSVPRRPGQRRPPPPPPPPPLPPPPPSPLPPLPLPPLKKRGNHSTGLCLLVMFFMVLVALVGLGLGMFQLFHLQKELAELRESTSQKHTASSLEKQIGHPSPPPEKKEQRKVAHLTGKPNSRSMPLEWEDTYGIVLLSGVKYKKGGLVINETGLYFVYSKVYFRGQSCTNLPLSHKVYMRNSKYPQDLVMMEGKMMSYCTTGQMWAHSSYLGAVFNLTSADHLYVNVSELSLVNFEESQTFFGLYKL
What is the function of this protein?
Cytoplasmic form induces gene transcription inhibition.
What are the official names of this protein?
Tumor necrosis factor ligand superfamily member 6, CD95 ligand, CD95-L, Fas antigen ligand, Fas ligand, FasL.
What is the protein family that this protein belongs to?
Belongs to the tumor necrosis factor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Cytoplasmic vesicle lumen. Lysosome lumen. Note=Colocalizes with the SPPL2A protease at the cell membrane. Is internalized into multivesicular bodies of secretory lysosomes after phosphorylation by FGR and monoubiquitination. SUBCELLULAR LOCATION: [Tumor necrosis factor ligand superfamily member 6, soluble form]: Secreted. Note=May be released into the extracellular fluid by cleavage from the cell surface. SUBCELLULAR LOCATION: [FasL intracellular domain]: Nucleus. Note=The FasL ICD cytoplasmic form is translocated into the nucleus.
Protein: DHE4_HALSI
Sequence: MPEANPFESLQEQLDDAGEFLDVNADVLERLKHPERVLETTLSVEMDDGTIETFKAFRSQFNGDRGPYKGGIRYHPGVTRDEVKALSGWMVYKTAVADIPYGGGKGGIILDPEEYSDSELERITRAFATELRPFIGEDKDVPAPDVNTGQREMNWIKDTYETLEDTTAPGVITGKALENGGSEGRVNATGRSTMFAAREVFDYLDRDLSDATVAVQGYGNAGSVAAKLIADQGADVVAVSDSSGAVHNPDGLDTRAVKAFKTETGSVSGYEGATEELSNEALLTMDVDLLVPAALENAIDEDLAHDVDADVVVEAANGPLTPDADDVLTERGVTVVPDILANAGGVTVSYFEWVQNRQRFQWTEDRVNEELEAIITDAFDAMTDAHEDAGTPNLRTAAYVVAVQRVVDAYEGSGSWP
What are the official names of this protein?
NADP-specific glutamate dehydrogenase A1.
What is the protein family that this protein belongs to?
Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
Protein: VF196_IIV6
Sequence: MSFMLYLDKADFILSQPPPSNNQEKKKILKNRITNSFSLIMFSGNNCTYCQELKPIFKKLVGTIPNCQIGTVNVSLQPELAELSQQTTTPIRYVPLILFYINGTPFKEFGGNYTEDNLRQFVKEVSIKAYEIIGTPQQEEGSISQHSVGKAVSKRVCYLNFDNAYNGTPPPSFD
What are the official names of this protein?
Uncharacterized protein 196R.
What is the protein family that this protein belongs to?
Belongs to the IIV-6 196R family.
Protein: THIO_STRCL
Sequence: MAGVLKNVTDDTFEADVLKSEKPVLVDFWAEWCGPCRQIAPSLEAITEHGGQIEIVKLNIDQNPATAAKYGVMSIPTLNVYQGGEVVKTIVGAKPKAALLRPGPVPR
What is the function of this protein?
Component of the thioredoxin-thioredoxin reductase system.  Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
What are the official names of this protein?
Thioredoxin, Trx.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
Protein: RL26_LITLI
Sequence: MKFNKMVSSDRGKNRKRHFNAPSHMRRKIMSSPMSKELRQKYNCRSMPIRKDDEVQVVRGHFKGQQVGKVVQVYRKKFVVHIERIQREKANGATVYVGIHPSKVLIVKLKMDKDRKRILDNKAKSRAKALAEKGKYTEETMETS
What are the official names of this protein?
60S ribosomal protein L26.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: PEX3_KLULA
Sequence: MTGNRSLVQRHRKKFVVSSVLFATLFATCAITVYFSKRWLYKQHLKMTEQRFVKEQIKRRFVQTQQDSLYTLYELMPVMTLVLAKDFDLDSIVEALKGKKLQKKLSKGEIAGNELENEGLSSGMSAMTPAPSVSAKSPQSADTTSVSETSTKSKAELWDDLKLKAITKIIILSYTTSLLMLLTRLQLNILARREYLDTAINSAMEKEREKKANQYSVLSWFSSWITEKSNNLPSEKADPRNSDGTIDTDTRSIASTANPEKSRYVNEQAFLSLSWWLLNRGYLQYKSIIEQLVKEEFQNSNPRDIMTMDEFSGKISKIFVTTNKQFFQQPQSNEMFISCLLPEPNLERFVLQQTLEQDALKVLYEDNLLLKQLVQETNKCLQSPGTWIVLESLIDETFHTIMEQIEDNVNSKSKPKSNDDDTKVVDISKNSYQIALFSIATKDCTNEMLKAGLVSMNNKFLQKLHSISALDDLSACVYSNFGL
What is the function of this protein?
Involved in peroxisome biosynthesis.
What are the official names of this protein?
Peroxisomal biogenesis factor 3, Peroxin-3, Peroxisomal membrane protein PAS3.
What is the protein family that this protein belongs to?
Belongs to the peroxin-3 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Single-pass membrane protein.
Protein: RLME_METHJ
Sequence: MGSQWGKDKAYLKAKQSGYRSRAAMKLKEIIQKNPVIRPDDNILDLGAAPGSWLQVLREMTNGVIVGVDLNPILPIEGVRTIIGDFSDPVVIAQIRELMPEVNGIVCDASPKLSGQRSFDQARAIELNEMALGVARQLLKQGGNMIMKSFQGEDFSWLYNRVKQEFYSVRTYKAHTTRKGSTEMYIIAKNFIGTHQGLEESVSDGSA
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_BRUO2
Sequence: MAEAKALPRFKKLYQDNIRKALLEEFKYDNEMQIPRITKVVLNMGVGEATGDSKKPAVAAEDLAMIAGQKAVVTRARNSIATFKLREGMPIGAKVTLRQDRMYEFLDRLITIALPRVRDFRGLNPKSFDGRGNYAMGIKEHIVFPEINYDKVDQIWGMDIIVCTTAKTDDEARSLLRAFNFPFRQ
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: GGR_METPE
Sequence: MKTEYDILIIGAGPGGAMAAKTAAEEGLSVLMVEKRPAIGTPVRCAEGVGKELLHEFIGPDPAWISADIERATIVGPDGTSMSLEAQRAGNEVGYILDRKVFDRALVWQAAEAGAEVQVKTRAIAPILENGFVRGARLQGYGTTTDVRAKVVIAADGVESKFARWCGVDTAVPVNEIETCAQYLLTDIDIDESATVFYLGNEIAPEGYAWVFPKGKRTANVGLGISGKKNLPGNRPIDYLNRFVEKNFPNGKTIECIVGGVSVCTPLASTVSDGLMIVGDAARISDPLTGGGIYNAMYSGRLAAQVAIECIKRGDCSRAALAAYDQQWRVSAMGKALDRNYKIKEYFIRQSDEKLNALAHSFKKINMEKFSTLELIKELIKHNPKLLFELKTLRDSLNS
What is the function of this protein?
Is involved in the reduction of 2,3-digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids.  Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains.
What are the official names of this protein?
Digeranylgeranylglycerophospholipid reductase, DGGGPL reductase, 2,3-bis-O-geranylgeranylglyceryl phosphate reductase, Geranylgeranyl reductase, GGR.
What is the protein family that this protein belongs to?
Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily.
Protein: SUCC_BRUSU
Sequence: MNIHEYQAKRLLHTYGAPIANGVAVYSVEQAEEWAKTLPGPLYVVKSQIHAGGRGKGKFKELPADAKGGVRLAKSVEEVVANAKEMLGNTLVTKQTGEAGKQVNRLYIEDGADIERELYLSILIDRSVGRPAFVVSTEGGMDIEAVAEETPEKIVTVAIDPAKGVTDEDANKLADALKLEGGAREDGLKLFPILYKAFTEKDMSLLEINPLIVMTNGRVRVLDAKVSFDNNALFRHPDIVELRDLTEEDPKEIEASKYDLAYVALDGNIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGGGASKEKVTAAFKIITADPAVEGILVNIFGGIMKCDVIAEGVIAAVKEVGLKVPLVVRLEGTNVELGKKIINESGLNVISADDLDDAAQKIVAAVKGN
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: TFF1_MOUSE
Sequence: MEHKVICVLAVVLMLAFGSLAQAQAQAQAQEETCIMAPRERINCGFPGVTAQQCTERGCCFDDSVRGFPWCFHPMAIENTQEEECPF
What is the function of this protein?
Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents.
What are the official names of this protein?
Trefoil factor 1, Protein pS2.
What are the subcellular locations of this protein?
Secreted.
Protein: AIS_SHISS
Sequence: MLAFCRSSLKSKKYFIILLALAAIAGLGTHAAWSSNGLPRIDNKTLARLAQQHPVVVLFRHAERCDRSTNQCLSDKTGITVKGTQDARELGNAFSADIPDFDLYSSNTVRTIQSATWFSAGKKLTVDKRLLQCGNEIYSAIKDLQSKAPDKNIVIFTHNHCLTYIAKNKRDATFKPDYLDGLVMHVEKGKVYLDGEFVNH
What is the function of this protein?
Catalyzes the dephosphorylation of heptose(II) of the outer membrane lipopolysaccharide core.
What are the official names of this protein?
Lipopolysaccharide core heptose(II)-phosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. Ais subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: ELAC_TRIVU
Sequence: MKFTIIALCLALSLVGMTSSEKLLDRIRANSLENLSRLVPSLCLLPSGRGNCDSQILRYFYNATSHTCEVFLYSGCNGNGNNFDSLECCLKTCRLNKYRNNN
What are the official names of this protein?
Early lactation protein.
What are the subcellular locations of this protein?
Secreted.
Protein: MNME_PHOV8
Sequence: MKMINQDTICAIATAQGGAIGIIRVSGPKAIEITSRIFTPATGKPLTERAPYTLTFGKICSPKRKINNTLFQQTSEIPQEKSETLQKTSSITSSAEEVIDEVLISLFRAPHSYTGEDSTEIMCHGSSYILQQVIQLLIYNGCRAALPGEYTQRAFLNGKMDLSQAEAVADLIASSSASTHRLAMSQMRGGFSKELSNLRNQLLHFTSLMELELDFSDHEELEFANRDELSSLATHIEQVIARLAHSFSVGNAIKNGIPVAIIGETNAGKSTLLNALLNEEKAIVSDIHGTTRDVIEDTINLQGVTFRFIDTAGIRQTNDTIENLGIERTFQKMDQAYVILWMIDSTDAQRRFEELKADILPHCEGKKMIILFNKSDLLLATQKEELSAIFADMKVEKLFISAKKRENITILEKKLVQAAALPEVNQNDIIITNVRHYEALTRALDSIHRVQEGLQLELSGDLVSEDLRQCIHELSEIVAEGGITSEETLQNIFQNFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA2AF_CROVV
Sequence: MRTLWIVAVLLLGVEGSLVQFEMMIIKVAKRSGLFWYGAYGCYCGWGGQGRPQDATDRCCFVHDCCYGKATDCNPKTVSYTYSVKNGEIICEDDDPCKKQVCECDRVAAVCFRDNIPSYNNNYKRFPAENCREEPEPC
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that shows very low inhibition of ADP-induced platelet aggregation in platelet-rich plasma of human, rabbit and guinea pig.  In vivo, shows efficient edema-inducing activities in rat paws.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Acidic phospholipase A2 Cvv-E6f, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MOAE_STAAN
Sequence: MKQFEIVIEPIQTEQYREFTINEYQGAVVVFTGHVREWTKGVKTEYLEYEAYIPMAEKKLAQIGDEINEKWPGTITSIVHRIGPLQISDIAVLIAVSSPHRKDAYRANEYAIERIKEIVPIWKKEIWEDGSKWQGHQKGNYEEAKREE
What is the function of this protein?
Converts molybdopterin precursor Z to molybdopterin.  This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group.  The sulfur is provided by MoaD.
What are the official names of this protein?
Molybdopterin synthase catalytic subunit, MPT synthase subunit 2, Molybdenum cofactor biosynthesis protein E, Molybdopterin-converting factor large subunit, Molybdopterin-converting factor subunit 2.
What is the protein family that this protein belongs to?
Belongs to the MoaE family.