PharMolix/UniProtQA huggingface dataset:
Protein: HBA_HUMAN
Sequence: MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR
What is the function of this protein?
Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1 (PubMed:18077343).  Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling (PubMed:18077343).
What are the official names of this protein?
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: EFG_GEMAT
Sequence: MPRTTPLEHYRNIGIMAHIDAGKTTTTERILYYTGKSHKIGEVHDGAATMDWMEQEQERGITITSAATTCFWMRHGQSHEKGTGAEYRINIIDTPGHVDFTVEVERSLRVLDGAVTLLDSVAGVEPQTETVWRQADRYRVPRMIFSNKMDRVGANFDRCLAMIRDRLSKRAFPLQLPVGSGETFTGHIDVLERKQYIFHDETMGKTFSVVDVPEEFKDACEIARHEAIEAAVEHDETLMEKYLAGEELSMEEIRRAIRQATIAMEFIPVFCGASFKNKGVQALLDAVIDYLPAPIDVPAIKGHLPHHDETFIEAPIKDDAPFAALAFKIATDPFVGKLTFFRVYSGVMASGSYVYNSTKDKRERVGRLLQMHANKREEIEEVRAGDIAAAIGLKDTRTGDTLCTEDNPIILEAMKFPNPVIDVAIEPKTKADQDKLAIALQKLAEEDPTFRVRSDAETGQTIIAGMGELHLEIIVDRMMREFKVDANVGRPQVAYRETIKKRVEKIEGKFVRQSGGKGQYGHVVINMEPSEQGQGYVFEDKVVGGVIPREYIGPVEQGIKEALETGVLAGYPVVDIKVQLVYGSYHDVDSSEMAFKIAGSMAFKEAAKQASPCLLEPVMKVEVVSPEAYMGDVLGDLSSRRGKIGGMTQRGEAQVISATVPLAEMFGYSTKLRSMSQGRAVYSMEFSHYEEVPKSKAEEIISKVKA
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAGB_HAEIE
Sequence: MRFIPLQTEQQVSCWAAQHIINRINDFKPTAERPFVLGLPTGGTPLKTYQELIRLYQAGKVSFKHVVTFNMDEYVALPEEHPESYHSFMYNNFFNHIDILPENINILNGNTDDHNAECHRYEEKIKSYGKIHLFMGGVGVDGHIAFNEPASSLSSRTRIKTLTQDTLIANSRFFNNDVTQVPKYALTIGVGTLLDAEEVMILATGHQKALAVQAAVEGSINHLWTVSALQMHRHFLLVCDEAAQQELKVKTVKYFTELEGAVAGTDYQGK
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: RL16_PSEP1
Sequence: MLQPKRTKFRKQMTGHNRGLALRGSKVSFGEFALKAVARGRLTARQIESARRALTRHVKRGGKIWIRVFPDKPISKKPLEVRMGKGKGSVEYWVAQIQPGKVLYEIEGVSEELAREAFALAAAKLPLATSFVKRTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: TETN_MOUSE
Sequence: MGFWGTYLLFCLFSFLSQLTAESPTPKAKKAANAKKDLVSSKMFEELKNRMDVLAQEVALLKEKQALQTVCLKGTKVNLKCLLAFTQPKTFHEASEDCISQGGTLGTPQSELENEALFEYARHSVGNDANIWLGLNDMAAEGAWVDMTGGLLAYKNWETEITTQPDGGKAENCAALSGAANGKWFDKRCRDQLPYICQFAIV
What is the function of this protein?
Tetranectin binds to plasminogen and to isolated kringle 4.  May be involved in the packaging of molecules destined for exocytosis (By similarity).  Plays a role in retinal function (By similarity).
What are the official names of this protein?
Tetranectin, TN, C-type lectin domain family 3 member B, Plasminogen kringle 4-binding protein.
What are the subcellular locations of this protein?
Secreted.
Protein: Y2279_SHEPW
Sequence: MAFDKKLLDIVACPVCKGKLEYNKQDNQLICKFDKIAYPINDGIPVLLENKAEPLAE
What are the official names of this protein?
UPF0434 protein swp_2279.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: MNMG_PARXL
Sequence: MLFPTEFDVIVVGGGHAGTEAALASARMGNTTLLLTHNIETLGQMSCNPSIGGIGKGHLVKEVDALGGAMAAATDEGGIQFRILNSSKGPAVRATRAQADRLLYKQAIRHRLENQPNLWLFQQAVDDLMVEGDRVVGAVTQVGIRFRGRAVVLTAGTFLDGKIHVGLNNYTGGRAGDPAAVSLSARLKELKLPQGRLKTGTPPRIDGRTIDFSQLEEQPGDLDPVPVFSFLGRVEQHPRQVPCWVTHTNARTHDIIRGGLDRSPMYTGVIEGVGPRYCPSIEDKIHRFASKESHQIFLEPEGLTTNEFYPNGISTSLPFDVQLELVRSMRGLEHAHILRPGYAIEYDYFDPRGLKASLETKVISGLFFAGQINGTTGYEEAAAQGLLAGINAGLYVQGKEAWCPRRDQAYLGVLVDDLVTRGVSEPYRMFTSRAEYRLSLREDNADMRLTEIGRELGVVDDVRWDAFSRKRDAVSRETERLRTTWVNPKTLSADEATALLGKPIDHEYSLADLLRRPGVSYDGVCALRAGACAAPETLAEDDVLLAQIKEQIEIGIKYQGYIDRQAGEIERNEAHESTRLPEGLDYAEVRGLSFEARQKLTQFRPETIGQASRISGITPAAISLLMVHLKRGLGRRPTKPAESGTDSAPVTQ
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMY_DERPT
Sequence: KYHNPHFIGNRSVITHLMEWKYDDIGDECERFLGPYGYGGVQVSPVNEHAILDRRPWYERYQPVSYDIRTRSGDEQQFRRMVKRCNKAGVRIYVDIVLNHMTGAQSGKGTNGHHYDGNTLQYPGVPFGPNDFHGHESCPTQDLEIHDYTNPKEARNCRLSGLRDLKQQSEYVRQKQVDFLNHLIDIGVAGFRSDASTHQWPDDLRSIYSRLHNLNKEFFPENSQPFIYHETIYYGGNGINSNEYTSLGRIIEFRFYKEITNVFRGNNPLHWLKNFGTEWGLVPSGDALVMIDSHDLRVGHTGKLGFNINCFEGRLLKAATAFMLAWNYGVPRVMSSYFWNQIIKDGKDVNDWVGPPSDKNGNILSVHPNPDMTCNHEWICEHRWREIYNMVKFRMIAGQEPVHNWWDNGDYQIAFSRGNRAFIAINLQKNQQNLQQKLHTGLPAGTYCDIISGNLIDNKCTGKSIHVDKNGQADVYVGHDEFDAFVAYHIGARIVS
What is the function of this protein?
Aids in the digestion of starch and glycogen derived from food, such as skin scales, fungi and bacteria.
What are the official names of this protein?
Alpha-amylase, 1,4-alpha-D-glucan glucanohydrolase, Allergen Der p IV, Mite group 4 allergen Der p 4.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Secreted.
Protein: NUOK_ECOBW
Sequence: MIPLQHGLILAAILFVLGLTGLVIRRNLLFMLIGLEIMINASALAFVVAGSYWGQTDGQVMYILAISLAAAEASIGLALLLQLHRRRQNLNIDSVSEMRG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NPCL1_HUMAN
Sequence: MAEAGLRGWLLWALLLRLAQSEPYTTIHQPGYCAFYDECGKNPELSGSLMTLSNVSCLSNTPARKITGDHLILLQKICPRLYTGPNTQACCSAKQLVSLEASLSITKALLTRCPACSDNFVNLHCHNTCSPNQSLFINVTRVAQLGAGQLPAVVAYEAFYQHSFAEQSYDSCSRVRVPAAATLAVGTMCGVYGSALCNAQRWLNFQGDTGNGLAPLDITFHLLEPGQAVGSGIQPLNEGVARCNESQGDDVATCSCQDCAASCPAIARPQALDSTFYLGQMPGSLVLIIILCSVFAVVTILLVGFRVAPARDKSKMVDPKKGTSLSDKLSFSTHTLLGQFFQGWGTWVASWPLTILVLSVIPVVALAAGLVFTELTTDPVELWSAPNSQARSEKAFHDQHFGPFFRTNQVILTAPNRSSYRYDSLLLGPKNFSGILDLDLLLELLELQERLRHLQVWSPEAQRNISLQDICYAPLNPDNTSLYDCCINSLLQYFQNNRTLLLLTANQTLMGQTSQVDWKDHFLYCANAPLTFKDGTALALSCMADYGAPVFPFLAIGGYKGKDYSEAEALIMTFSLNNYPAGDPRLAQAKLWEEAFLEEMRAFQRRMAGMFQVTFMAERSLEDEINRTTAEDLPIFATSYIVIFLYISLALGSYSSWSRVMVDSKATLGLGGVAVVLGAVMAAMGFFSYLGIRSSLVILQVVPFLVLSVGADNIFIFVLEYQRLPRRPGEPREVHIGRALGRVAPSMLLCSLSEAICFFLGALTPMPAVRTFALTSGLAVILDFLLQMSAFVALLSLDSKRQEASRLDVCCCVKPQELPPPGQGEGLLLGFFQKAYAPFLLHWITRGVVLLLFLALFGVSLYSMCHISVGLDQELALPKDSYLLDYFLFLNRYFEVGAPVYFVTTLGYNFSSEAGMNAICSSAGCNNFSFTQKIQYATEFPEQSYLAIPASSWVDDFIDWLTPSSCCRLYISGPNKDKFCPSTVNSLNCLKNCMSITMGSVRPSVEQFHKYLPWFLNDRPNIKCPKGGLAAYSTSVNLTSDGQVLDTVAILSPRLEYSGTISAHCNLYLLDSTSRFMAYHKPLKNSQDYTEALRAARELAANITADLRKVPGTDPAFEVFPYTITNVFYEQYLTILPEGLFMLSLCLVPTFAVSCLLLGLDLRSGLLNLLSIVMILVDTVGFMALWGISYNAVSLINLVSAVGMSVEFVSHITRSFAISTKPTWLERAKEATISMGSAVFAGVAMTNLPGILVLGLAKAQLIQIFFFRLNLLITLLGLLHGLVFLPVILSYVGPDVNPALALEQKRAEEAVAAVMVASCPNHPSRVSTADNIYVNHSFEGSIKGAGAISNFLPNNGRQF
What is the function of this protein?
Plays a major role in cholesterol homeostasis (PubMed:22095670).  Critical for the uptake of cholesterol across the plasma membrane of the intestinal enterocyte (PubMed:22095670).  Involved in plant sterol absorption, it transports sitosterol, although at lower rates than cholesterol (By similarity).  Is the direct molecular target of ezetimibe, a drug that inhibits cholesterol absorption and is approved for the treatment of hypercholesterolemia (PubMed:15928087).  May have a function in the transport of multiple lipids and their homeostasis, thereby influencing lipid metabolism regulation (PubMed:15671032).  May be involved in caveolin trafficking from the plasma membrane (By similarity).  In addition, acts as a negative regulator of NPC2 and down-regulates its expression and secretion by inhibiting its maturation and accelerating its degradation (PubMed:22095670).
What are the official names of this protein?
NPC1-like intracellular cholesterol transporter 1, NPC1L1, Niemann-Pick C1-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the patched family.
Protein: MCES_ASPNC
Sequence: MASKEEERTGQRPSISMYDPARDRWEEQPVVPAEPASASASIEATPTQTSEAKPVHDSTVTSTSESLHLPQTTTIEPSQQPEQQQKQPPIPTPPSSQSRRKHKINKMGDYYRSGSADAYAEQSSPAADSHKRKLEDETSEQQPPADQANDRPISKRKRLEERHQKLRKRGQAPPSAYSRRDGDETAARAAPRPRSPSPPLPPRSPSPEVQARQRKRPGGGARRGLVDPQTLRRRQEERERALEEDAMRNSQSRGVTDIVRQHYNAVPQRGREWRKTESKIKGLRSFNNWVKSTLIQKFSPDEEFEKRLLVIDLGCGKGGDLGKWQLAPQPVDLYVGLDPAEVSIIQARERYAGMRSGRGPRGGRRGGPPLFHGEFRSKDCFGEWLGDVDIVQQVGIDPNVGPGGSMMASRWGGGGFDVVTSMFAIHYAFESEEKARQMLRNVAGCLKKGGRFIGVCPNSDIISARVEEEAKAEWGNSIYRVRFPGDTPEDGIFRPPFGWKYSYFMEEAVGEIPEYVVPWEAFRALTEEYNLELQYRKPFMEVWRDEKDDPELGPLSERMGVRDRTTGELTMTPEEQEAVSKYTPLGFTSAEGESANGTGFYHAFCFYKV
What is the function of this protein?
Responsible for methylating the 5'-cap structure of mRNAs.
What are the official names of this protein?
mRNA cap guanine-N7 methyltransferase, mRNA (guanine-N(7))-methyltransferase, mRNA cap methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRUC_ECOL6
Sequence: MLEILYQDEWLVAVNKPSGWLVHRSWLDRDEKVVVMQTVRDQIGQHVFTAHRLDRPTSGVLLMGLSSEAGRLLAQQFEQHQIQKRYHAIVRGWLMEEAVLDYPLAEELDKIADKFAREDKGPQPAVTHYRGLATVEMPVATGRYPTTRYGLVELEPKTGRKHQLRRHLAHLRHPIIGDSKHGDLRQNRSGAEHFGLQRLMLHASQLSLTHPFTGEPLAIHAGLDDTWMQALSQFGWRGLLPENERVEFSAPSGQDGEISS
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-65 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase C, tRNA pseudouridine(65) synthase, tRNA pseudouridylate synthase C, tRNA-uridine isomerase C.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RluA family.
Protein: RNPH_SALPK
Sequence: MRPAGRSANQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTASIEEGVPRFLKGQGQGWITAEYGMLPRATHTRNAREAAKGKQGGRTMEIQRLIARALRAAVDLKTLGEFTITLDCDVIQADGGTRTASITGACVALADALNKLVANGKLKTNPMKGMVAAVSVGIVNGEAICDLEYVEDSAAETDMNVVMTEDGRIIEVQGTAEGEPFSHEELLTLLALARGGIESIVATQKAALEN
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: ACCD_WIGBR
Sequence: MSWIERILKKNTITKKTNIPEGIWVKCNNCNQMIYKIELEKNLEVCPKCNFHMRISARKRLEKFLDKNNILELGKNLEPKDILKFKDTKKYKDRLYIAQKLTKEKDAIIVMKGSLYKMPIVAAAFEFSFIGGSMSSVVGERFVFGVNESIKCNCPMVCFSASGGARVQEALISLMQMAKTSAALSKLRKKKIPYISVMTDPSMGGVSASIAMLGDINIAEPKALIGFAGPRVIEQTVREKLPDKFQKSEFLIQKGIIDLIIKRKNMRFSIGKLLAKITNKPEPKKE
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAP14_ARATH
Sequence: MALCGVCSTPNLPNLQVFRSVRNSSIGYKRNHSLWQLRSSSFRAKSVIFHCSSSLRQSPSNVEEIDDNPSVSLEDESAHVMQFKWSDFRILDRVSIGHGGRADELVFEAIVQVPDSPLFNQGVVLRKLNTTRAQRRGRRAIEVFKKLVRRRLLYHSYSMQVHGYITNNLSDDQYSFTLVHGCHGSFSIRHWLQQSDWIPTLEATLALDEESFRRVGDDTTGGPAVSRQLRLIRTLMRDILIGVNYLHSHGLAHTELRLENVHISPVDRHIKVGILGNAADFNGDVPSTSNAYSTMDRRQMMIAFDMRCVGFMMAKMVLQELMDPLIFAKLKSFLAKGNDPSSLREFFVTTLNTNSESGNTGVQILDRNWGAGWHLLSLLIATRPSERISCLDALKHPFLCGPRWRVAPSMDIIRWGLGSTAVKISEEYIYRMPQRQRLAHFIGLMEMLNPYPKPNCWLELLPGRWRLLYSTGKHIGLTLRQPSTRALIGNVHLTITRASESINNTSLSFTSDIRFTAITSKDWPHNKIGAAGKLQTLSQFRLIAGKRLYLKEEKKNIGKFSMGEPDAEEGLAEKLETEKWKKVVPFKEFPSSLPVAKLVSGEIEVTMNMNDHIDSPGSVIGEVRKQIPPEMFDLSKLVCGTYIDSRLLVLRCVNGSALLFTRSSLDHKSM
What is the function of this protein?
Directly regulated by DOF3. 6/OBP3; unknown function.
What are the official names of this protein?
Probable plastid-lipid-associated protein 14, chloroplastic, AtPap14, Fibrillin-11, OBP3-responsive protein 1.
What is the protein family that this protein belongs to?
Belongs to the PAP/fibrillin family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL11_BACC7
Sequence: MAKKVIKMVKLQIPAGKANPAPPVGPALGQAGVNIMGFCKEFNARTADQAGLIIPVEITVFEDRSFTFITKTPPAAVLLKKVAGIESGSGEPNRNKVATVKRDKVREIAETKMPDLNAASVEAAMRMVEGTARSMGIVIED
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: DHYS_SULIL
Sequence: MINREDLLKNPVEDIALSDLEKYSDIVNVFDKIYGFSSEGIVRGSKILKEMIKDADLRFLSFTANLVSTGLRGLFADLVKRGYFNIIVTTGGTIDHDLARSFGGVYYKGSFDIDDAMLKDLEIHRLGNVLVPFESYGKVIEEIVRKFLPEIAKDKKEIPAYELLWEFGKRISDSNSILRAAYEKKVPVIVPGIVDGSFGTNLFIQSQFLNFKINLFEDMRLIKDLVFSCKKSGALIIGGGISKHHTIWWNQFKDGLDYAVYVTTAQEYDGSLSGAKPREAISWNKIRPNAKHATIYGDATIIVPILAASLLS
What is the function of this protein?
Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
What are the official names of this protein?
Probable deoxyhypusine synthase, DHS.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine synthase family.
Protein: LUXS_CAMJD
Sequence: MPLLDSFKVDHTKMPAPAVRLAKVMKTPKGDDISVFDLRFCVPNKDIMSEKGTHTLEHLFAGFMREHLNSNAVEIIDISPMGCRTGFYMSLIGTPDEKSVVKAWENSMQDVLKVKSQEDIPELNIYQCGSCKLHSLDEAKQIAQKVLNSGIGVMNNAELKLENL
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: FPG_STRA1
Sequence: MPELPEVETVRKGLERLVVNQEIASITIKVPKMVKTDLNDFMISLPGKTIQQVLRRGKYLLFDFGEMVMVSHLRMEGKYLLFPNKVPDNKHFHLYFKLTNGSTLVYQDVRKFGTFELVRKSSLKDYFTQKKLGPEPTADTFQFEPFSKGLANSKKPIKPLLLDQRLVAGLGNIYVDEVLWAAKIHPQRLANQLTESETSLLHKEIIRILTLGIEKGGSTIRTYKNALGEDGTMQKYLQVYGKTGQPCPRCGCLIKKIKVGGRGTHYCPRCQCL
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: Y1311_STAAB
Sequence: MVKTVYVTGYKSFELNIFKDDAPEIHYLKQFIKHKIEQLLDEGLEWVLIQGQMGIELWTTEVVIELQRTYDSLKFAVITPFQGHTEKWNEHNQSKYANIIKHADYVDSIFHTSYQGPFQFKQADQFMLEHSDQTLLIYDEEQEASPKFFKQMLVDFMDKTNYTCDIVTFDELTAFINDLQWSEDQSF
What are the official names of this protein?
UPF0398 protein SAB1311c.
What is the protein family that this protein belongs to?
Belongs to the UPF0398 family.
Protein: VP6_ROTRH
Sequence: MDVLYSLSKTLKDARDKIVEGTLYSNVSDLIQQFNQMIITMNGNEFQTGGIGNLPIRNWNFDFGLLGTTLLNLDANYVETARNTIDYFVDFVDNVCMDEMVRESQRNGIAPQSDSLRKLSGIKFKRINFDNSSEYIENWNLQNRRQRTGFTFHKPNIFPYSASFTLNRSQPAHDNLMGTMWLNAGSEIQVAGFDYSCAINAPANIQQFEHIVQLRRVLTTATITLLPDAERFSFPRVINSADGATTWYFNPVILRPNNVEVEFLLNGQIINTYQARFGTIIARNFDTIRLSFQLMRPPNMTPAVAALFPNAQPFEHHATVGLTLRIESAVCESVLADASKTMLANVTSVRQEYAIPVGPVFPPGMNWTDLITNYSPSREDNLQRVFTVASIRSMLVK
What is the function of this protein?
Intermediate capsid protein that self assembles to form an icosahedral capsid with a T=13 symmetry, which consists of 230 trimers of VP6, with channels at each of its five-fold vertices (PubMed:21157433).  This capsid constitutes the middle concentric layer of the viral mature particle (PubMed:21157433).  The innermost VP2 capsid and the intermediate VP6 capsid remain intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus (By similarity).  Nascent transcripts are transcribed within the structural confines of this double-layered particle (DLP) and are extruded through the channels at the five-fold axes (By similarity).  VP6 is required for the transcription activity of the DLP (By similarity).
What are the official names of this protein?
Intermediate capsid protein VP6.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP6 family.
What are the subcellular locations of this protein?
Virion. Note=Component of the intermediate capsid (PubMed:19036817, PubMed:21157433). Also found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging (Potential).
Protein: RB27B_BOVIN
Sequence: MTDGDYDYLIKLLALGDSGVGKTTFLYRYTDNKFNPKFITTVGIDFREKRVAYNTQGPNGPTGKAFKVHLQLWDTAGQERFRSLTTAFFRDAMGFLLMFDLTSQQSFLNVRNWMSQLQANAYCENPDIVLIGNKADLPDQREVNERQARDLAEKYSIPYFETSAATGQNVEKAVETLLDLIMKRMEQCVEKTHIPDTVNGSSSGKLDGEKSAEKKCAC
What is the function of this protein?
Small GTPase which cycles between active GTP-bound and inactive GDP-bound states.  In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion (By similarity).  Plays a role in NTRK2/TRKB axonal anterograde transport by facilitating the association of NTRK2/TRKB with KLC1 (By similarity).  May be involved in targeting uroplakins to urothelial apical membranes (PubMed:14625374).
What are the official names of this protein?
Ras-related protein Rab-27B.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Membrane; Lipid- anchor. Late endosome.
Protein: Y1417_MYCTU
Sequence: MTAAPNDWDVVLRPHWTPLFAYAAAFLIAVAHVAGGLLLKVGSSGVVFQTADQVAMGALGLVLAGAVLLFARPRLRVGSAGLSVRNLLGDRIVGWSEVIGVSFPGGSRWARIDLADDEYIPVMAIQAVDKDRAVAAMDTVRSLLARYRPDLCAR
What are the official names of this protein?
Uncharacterized protein Rv1417.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GCS1_YEAST
Sequence: MSDWKVDPDTRRRLLQLQKIGANKKCMDCGAPNPQWATPKFGAFICLECAGIHRGLGVHISFVRSITMDQFKPEELLRMEKGGNEPLTEWFKSHNIDLSLPQKVKYDNPVAEDYKEKLTCLCEDRVFEEREHLDFDASKLSATSQTAASATPGVAQSREGTPLENRRSATPANSSNGANFQKEKNEAYFAELGKKNQSRPDHLPPSQGGKYQGFGSTPAKPPQERSAGSSNTLSLENFQADPLGTLSRGWGLFSSAVTKSFEDVNETVIKPHVQQWQSGELSEETKRAAAQFGQKFQETSSYGFQAFSNFTKNFNGNAEDSSTAGNTTHTEYQKIDNNDKKNEQDEDKWDDF
What is the function of this protein?
GTPase-activating protein (GAP) for ARF1 and ARF2.  Involved in intracellular vesicular transport.  Required for transport from the trans-Golgi network.  Implicated in the regulation of retrograde transport from the Golgi to the ER and in actin cytoskeletal organization.  May be involved in the maintenance of mitochondrial morphology, possibly through organizing the actin cytoskeleton in Saccharomyces.
What are the official names of this protein?
ADP-ribosylation factor GTPase-activating protein GCS1, ARF GAP GCS1.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Cytoplasm, perinuclear region. Golgi apparatus. Note=Found also in the mitochondria and in the perinuclear region.
Protein: YRKI_BACSU
Sequence: MKSDKVLDAKGLACPMPIVRTKKAMNELESGQILEVHATDKGAKNDLTAWSKSGGHDLLEQTDEGDILKFWIQKG
What are the official names of this protein?
Putative sulfur carrier protein YrkI.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
Protein: DADA_BURMA
Sequence: MRVVILGSGVVGVASAYYLARAGHEVTVIDREAGPALDTSFANAGQISPGYAAPWAAPGVPLKAVKWMFEKHAPLAIRLDGTRFQLQWMWQMLRNCTTERYALNKGRMVRLAEYSRDCLQALRAETAIQYEGRTGGTLQVFRTQQQLDGAAKDIAVLREANVPFELLSSDELKKAEPALAAVSHKLTGGLRLPGDETGDCQLFTTRLAALAEQLGVKFRFNTRIDALAVAGGKIAGVQCGGEMVRADAYVVALGSYSTNLVASLVKIPVYPLKGYSITAPIVDAAKAPVSTVLDETYKIAITRFDDRIRVGGMAEIVGFDKRLRDARRGTLEMCVNDLFPGGGDTAKATFWTGLRPMTPDGTPIVGRTPVPNLFLNTGHGTLGWTMSCGSGQLLADLMSGKKPAIRADDLSVHRYLSETDGEHRPAYA
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: RL9_STRPC
Sequence: MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATSQSIGELKGKQKAEEKAQAEILAEAQAVKAVLDEDKTRVQFQEKVGPDGRTFGSITAKKISEELQKQFGVKVDKRHIVLDHPIRAIGLIEVPVKLHKEVTAEIKLAITEA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.