PharMolix/UniProtQA huggingface dataset:
Protein: NCAP_I89A2
Sequence: MASQGTKRSYEQMETDGERQNATEIRASVGKMIDGIGRFYIQMCTELKLSDYEGRLIQNSLTVERMVLSAFDERRNRYLEEHPSAGKDPKKTGGPIYKRVGGRWMRELVLYDKEEIRRIWRQANNGDDATRGLTHMMIWHSNLNDTTYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGIGTMVMELIRMIKRGINDRNFWRGENGRKTRSAYERMCNILKGKFQTAAQRAMMDQVRESRNPGNAEIEDLIFSARSALILRGSVAHKSCLPACVYGPAVSSGYDFEKEGYSLVGIDPFKLLQNSQVYSLIRPNENPAHKSQLVWMACHSAAFEDLRLLSFIRGTKVSPRGKLSTRGVQIASNENMDNMESSTLELRSRYWAIRTRSGGNTNQQRASAGQISVQPTFSVQRNLPFEKSTVMAAFTGNTEGRTSDMRAEIIRMMEGAKPEEVSFRGRGVFELSDEKATNPIVPSFDMSNEGSYFFGDNAEEYDN
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: Y407_MYCPN
Sequence: MKKRTKYRYWLNSLAFFGCGVSVGAFFTLFLMGTQSDVSPLFVKNINIQLPSSTHQQKIEPLNLPTNISKTEIASWGSEFQSKVLDFYARDGEEHDNKIRYQLPSLSFAWTGGKELVSDFARLHGARNFVAYFDQYWRFWSNPNWPAGQVDRVDVLCEWNSDKQTISDINFSDQFVFASARFEGKIANFGFAGQTMKDINESFQERVLSIYKPRTLVYLTSQADAERVDYYEEFVNNLTALIKKQVGEKAEKDNFFILQLHWKTNDSAFNEKLSVLNFVALATVKQLTDQNRNFASKIKVVDHFEGDFVPSDWLSGNYLSEDKVSLSLQGEFAIGKQLAQVLKATGAEPLPVEVTEPSLEAIPINEETQFDVKNYYSFGHYHDTNVINDRIDFDDPNYNLETDFFNNAKANLVTTSNPFTVTWKTKTKELEIESTEVNPNGLQYQLSFASDFNARDIKKRPTSYLRWNGTITNKQIDISLYWKYIHKALDIKENEPLNYLLQITRTDGQGSYQVINGWINKEKDNTPTIFDFLKDKTQANWLFIGDSMTHGVGTDGYSSAPQLLEQSLKNDFGRYRDVVINSAINGSNTSLELYMQNHRFKQYKNIDVYVLNLGTNDINQLAQGVYTVEQYKHNLTQILDLLHTQSPQAHVVLANIAPSSLLRSSEKNWKTFNDFLEGIPKDSNYSSFVHLLDQKSLFLQLAKVSGIDINENKLFNTDFLKKSFYFADKFSHLSVNGNVEYMRNILTTVGFDWQNSAFASLGYLSFGYLKKPATVVELPEVTVDDQTGVLDIKQSVPPKLKVNKQGFEPVFITFTNTNNNEQVTVVLNNWSQWETHKTDFAPWLKCKHWNIDVKQIRRVKTTFRDQENANFFELIESKQ
What are the official names of this protein?
Uncharacterized protein MPN_407.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: HSYA_TOBAC
Sequence: MRVLFLIYLILSPFGAEARTLLENHEGLNVGSGYGRGANLPPPSPASSPPSKEVSNSVSPTRTDEKTSENTELVMTTIAQGENINQLFSFPTSADNYYQLASFKKLFISYLLPVSYVWNLIGSSSFDHDLVDIFDSKSDERYWNRKPLSPPSPKPADGQRPLHSY
What is the function of this protein?
Activates a lipid-based signal transduction pathway in which linolenic acid is converted to jasmonic acid, a potent activator of defense gene transcription, including proteinase inhibitors.
What are the official names of this protein?
Hydroxyproline-rich systemin A.
What are the subcellular locations of this protein?
Secreted.
Protein: TM10A_RAT
Sequence: MSSEVLPASIEPPNVEGKPGASDSEEERQKQRVDAEAQPISKRQLKKLMKQRLWEEQREQRKEKRKEKRKRKKLERRCQLESNSDGNDRKRIRRHVAPSNLRLIIDCSFDDLMVLKDIKKLHKQIQRCYAENRRASHPVQFYLTSHGGQLKKNMDENDQGWVNWKDIHIKSEHYSELIKKEDLVYLTSDSPNVLKDLDESKAYVIGGLVDHNHHKGLTFKQASSYGIKHAQLPLAEFVKMNSRKVLAVNHVFEIILEFLETGDWQEAFFTILPPRKGAVPAHKACESSPQDHQALPGGWDSAIEGEHGRDDPGSPHKEQQGQQSSSVSAVSPDPQ
What is the function of this protein?
S-adenosyl-L-methionine-dependent guanine N(1)-methyltransferase that catalyzes the formation of N(1)-methylguanine at position 9 (m1G9) in tRNAs.  Probably not able to catalyze formation of N(1)-methyladenine at position 9 (m1A9) in tRNAs.
What are the official names of this protein?
tRNA methyltransferase 10 homolog A, RNA (guanine-9-)-methyltransferase domain-containing protein 2, tRNA (guanine(9)-N(1))-methyltransferase TRMT10A.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. TRM10 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus.
Protein: CBY1_BOVIN
Sequence: MPLFGSTFSPKKTPPRKSASLSNLHNLDRSTREVELGLDYGTPTMNLAGQSLKFENGQWIAETGISGGVDRREAQRLRRRNQQLEEENNLLRLKVDILLDMLSETTAESHLMEKELDELKSVSRRRK
What is the function of this protein?
Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors.  Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins.  Promotes adipocyte and cardiomyocyte differentiation.
What are the official names of this protein?
Protein chibby homolog 1, Cytosolic leucine-rich protein, PIGEA-14, PKD2 interactor, Golgi and endoplasmic reticulum-associated 1.
What is the protein family that this protein belongs to?
Belongs to the chibby family.
What are the subcellular locations of this protein?
Nucleus speckle. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Golgi apparatus. Golgi apparatus, trans-Golgi network. Note=Nuclear, in a punctate manner (By similarity).
Protein: MINC_SHEPW
Sequence: MQTPSLELKGSSFTLSVLHINSQDMAVIAAELDSKLAIAPQFFLGAPLVVNLSAIKASDFDLLGLKEILTSRQLIIVGITSALPVINDMAKSIGLAIVKSGKAATNQPQMPKTTKIVKQNVRSGQQIYAKNGDLIVIGAVGNGAEVIADGSIHVYGALRGKAMAGAAGDRNAVIVAQKIEAELVSIAGQYWLTEHLQQNEAAQSGCIRLEGDSLTVESLPL
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: TRI32_MOUSE
Sequence: MAAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVRCPFCSKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRGCGRRLPRQFCRSCGVVLCEPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELTGELQRRKAALEGVSRDLQARYKAVLQEYGHEERRIQEELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCDYFLAKIKQADVALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQIGQAVKKPRTVNMEDSWAGEEGAASSASASVTFREMDMSPEEVAPSPRASPAKQRSSEAASGIQQCLFLKKMGAKGSTPGMFNLPVSLYVTSQSEVLVADRGNYRIQVFNRKGFLKEIRRSPSGIDSFVLSFLGADLPNLTPLSVAMNCHGLIGVTDSYDNSLKVYTMDGHCVACHRSQLSKPWGITALPSGQFVVTDVEGGKLWCFTVDRGAGVVKYSCLCSAVRPKFVTCDAEGTVYFTQGLGLNVENRQNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEILHFPKGGGYSVLIREGLTCPVGIALTPKGQLLVLDCWDHCVKIYSYHLRRYSTP
What is the function of this protein?
Has an E3 ubiquitin ligase activity (PubMed:14578165, PubMed:16816390).  Ubiquitinates DTNBP1 (dysbindin) and promotes its degradation (By similarity).  May ubiquitinate BBS2 (By similarity).  Ubiquitinates PIAS4/PIASY and promotes its degradation in keratinocytes treated with UVB and TNF-alpha (PubMed:14578165, PubMed:16816390)Also acts as a regulator of autophagy by mediating formation of unanchored 'Lys-63'-linked polyubiquitin chains that activate ULK1: interaction with AMBRA1 is required for ULK1 activation (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase TRIM32, RING-type E3 ubiquitin transferase TRIM32, Tripartite motif-containing protein 32.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localized in cytoplasmic bodies, often located around the nucleus.
Protein: PG053_MONPV
Sequence: MAETKEFKTLYNLFIDSYLQKLAQHSIPTNVTCAIHIGEVIGQFKNCALRITNKCMSNSRLSFTLMVESFIEVISLLPEKDRRAIAEEIGIDLDDVPSVVSKLEKNCNAYAEVNNIIDIQKLNIGECSAPPGQHMLLQIVNTGSAEANCGLQTIVKSLNKIYVPPIIENRLPYYDPWFLVGVAIILVIFTVAICSIRRNLALKYRYGTFLYV
What is the function of this protein?
Component of the entry fusion complex (EFC), which consists of 11 proteins.  During cell infection, this complex mediates entry of the virion core into the host cytoplasm by a two-step mechanism consisting of lipid mixing of the viral and cellular membranes and subsequent pore formation.
What are the official names of this protein?
EFC-associated protein OPG053.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG053 family.
Protein: CATZ_RAT
Sequence: MASSGSVQQLRLVLLMLLLAGAARASLYFRPGQTCYRPLHRDHLALLGRRTYPRPHEYLSPADLPKNWDWRNVNGVNYASVTRNQHIPQYCGSCWAHGSTSALADRINIKRKGAWPSTLLSVQNVIDCGNAGSCEGGNDLPVWEYAHKHGIPDETCNNYQAKDQECDKFNQCGTCTEFKECHTIQNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERMSNYTGGIYTEYQNQAIINHIISVAGWGVSNDGIEYWIVRNSWGEPWGERGWMRIVTSTYKGGTGSSYNLAIEEACTFGDPIV
What is the function of this protein?
Exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity (PubMed:12553736, PubMed:10615013).  Capable of producing kinin potentiating peptides (PubMed:10615013).
What are the official names of this protein?
Cathepsin Z, Cathepsin Y.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: FTHS2_STRP6
Sequence: MVLSDIEIANSVTMEPISKVADQLGIDKETLCLYGKYKAKIDARQLVALKDKPDGKLILVTAISPTPAGEGKTTTSVGLVDALSAIGKKAVIALREPSLGPVFGVKGGAAGGGHAQVVPMEDINLHFTGDFHAIGVANNLLAALIDNHIHHGNSLGIDSRRITWKRVVDMNDRQLRHIVDGLQGKVNGVPREDGYDITVASEIMAILCLSENISDLKARLEKIIIGYNFQGEPVTAKDLKAGGALAALLKDAIHPNLVQTLEHTPALIHGGPFANIAHGCNSVLATKLALKYGDYAVTEAGFGADLGAEKFIDIKCRMSGLRPAAVVLVATIRALKMHGGVPKADLATENVQAVVDGLPNLDKHLANIQDVYGLPVVVAINKFPLDTDAELQAVYDACDKRGVDVVISDVWANGGAGGRELAEKVVALAEQDNQFRFVYNEDDSIETKLTKIVTKIYGGKGIKLTPTAKRELAELERLGFGNYPICMAKTQYSFSDDAKKLGAPTDFIVTISNLKVSAGAGFIVALTGAIMTMPGLPKVPASETIDIDEEGNITGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase 2, Formyltetrahydrofolate synthetase 2, FHS 2, FTHFS 2.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: RT10_HUMAN
Sequence: MAARTAFGAVCRRLWQGLGNFSVNTSKGNTAKNGGLLLSTNMKWVQFSNLHVDVPKDLTKPVVTISDEPDILYKRLSVLVKGHDKAVLDSYEYFAVLAAKELGISIKVHEPPRKIERFTLLQSVHIYKKHRVQYEMRTLYRCLELEHLTGSTADVYLEYIQRNLPEGVAMEVTKTQLEQLPEHIKEPIWETLSEEKEESKS
What are the official names of this protein?
28S ribosomal protein S10, mitochondrial, MRP-S10, S10mt, Mitochondrial small ribosomal subunit protein uS10m.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PHAF1_HUMAN
Sequence: MLDLEVVPERSLGNEQWEFTLGMPLAQAVAILQKHCRIIKNVQVLYSEQSPLSHDLILNLTQDGIKLMFDAFNQRLKVIEVCDLTKVKLKYCGVHFNSQAIAPTIEQIDQSFGATHPGVYNSAEQLFHLNFRGLSFSFQLDSWTEAPKYEPNFAHGLASLQIPHGATVKRMYIYSGNSLQDTKAPMMPLSCFLGNVYAESVDVLRDGTGPAGLRLRLLAAGCGPGLLADAKMRVFERSVYFGDSCQDVLSMLGSPHKVFYKSEDKMKIHSPSPHKQVPSKCNDYFFNYFTLGVDILFDANTHKVKKFVLHTNYPGHYNFNIYHRCEFKIPLAIKKENADGQTETCTTYSKWDNIQELLGHPVEKPVVLHRSSSPNNTNPFGSTFCFGLQRMIFEVMQNNHIASVTLYGPPRPGSHLRTAELP
What is the function of this protein?
Plays a regulatory role in autophagic activity.  In complex with BCAS3, associates with the autophagosome formation site during both non-selective and selective autophagy.
What are the official names of this protein?
Phagosome assembly factor 1.
What is the protein family that this protein belongs to?
Belongs to the PHAF1 family.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure. Note=The BCAS3:PHAF1 complex is recruited to the preautophagosomal structures adjacent to the damaged mitochondria upon mitophagy in a PRKN-PINK1 dependent manner.
Protein: MBHS_AFIC5
Sequence: MTPTETFYEVMRRQGVTRRSFLKFCSLTATALGLGPAYTSEIAHAMETKPRTPVLWLHGLECTCCSESFIRSAHPLVKDVVLSMISLDYDDTLMAAAGHQAEAALADTIERYKGNYILAVEGNPPLNEDGMFCIIGGKPFVDQLRYAAKHAKAIISWGSCASHGCVQAARPNPTRATPVHQVITDKPIIKVPGCPPIAEVMTGVITYMLTFGKLPELDRTGRPKMFYSQRIHDKCYRRPHFDAGQFVESFDDEGARRGYCLYKVGCKGPTTYNACSTIRWNEGTSFPIQAGHGCIGCSEEGFWDKGSWYARLQDIHQFGIEANADQIGGTVAVGAAGAVAAHAAVSALKRAQTKRQTTTTTTPKEHV
What is the function of this protein?
This enzyme recycles the H(2) produced by nitrogenase to increase the production of ATP and to protect nitrogenase against inhibition or damage by O(2) under carbon- or phosphate-limited conditions.
What are the official names of this protein?
Uptake hydrogenase small subunit, Hydrogenlyase, Membrane-bound hydrogenase small subunit.
What is the protein family that this protein belongs to?
Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CXA1_CANLF
Sequence: MGGWSALAKLLGKVQAYSPAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPGCENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDGANVDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSVFEVAFLLIQWYIYGFSLSAVYTCKREPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFKGVKDRVKGQSDPYHATTGPLSPSKDCGSPEYAYFNGCSSPTAPLSPMSPPGYKLVTGDRNNSSCRNYNKQASEQNWANYSAEQNRMGQAGSTISNSHAQPFDFPDDNQNSKKLAAGHELQPLAIVDQRPSSRASSRASSRPRPDDLEI
What is the function of this protein?
Gap junction protein that acts as a regulator of bladder capacity.  A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.  May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph.  Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract.  May play a role in cell growth inhibition through the regulation of NOV expression and localization.  Plays an essential role in gap junction communication in the ventricles (By similarity).
What are the official names of this protein?
Gap junction alpha-1 protein, Connexin-43, Cx43.
What is the protein family that this protein belongs to?
Belongs to the connexin family. Alpha-type (group II) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. Endoplasmic reticulum. Note=Localizes at the intercalated disk (ICD) in cardiomyocytes and the proper localization at ICD is dependent on TMEM65.
Protein: EIF3K_DROVI
Sequence: MAHLVKMENGQSQTIQEMLGCIERYNPDHLKILESYVQDQAKNNTYDLEANLAVLKLYQFNPHMLNFDITYTILLKCLTNLPHTDFVMAKCLLLPQQMKDENVQTIIDLADILERADFTLFWQRAEVNRTMFRHITGFHDSIRKFVSHVVGTTFQTIKKDLLKELLGGIEDSTLENWIKRNGWKHQGHDLVVVATQDDKIKTKNITEKIEFENVGALMAQCI
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit K, eIF3k, eIF-3 p25.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit K family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_BURO1
Sequence: MAKISKRRQAFAAKVDRQKLYAIEDALSLVKECASAKFDESIDVAVQLGIDAKKSDQVVRGSVVLPAGTGKSVRVAVFAQGEKAEQARAAGAEIVGMEDLAEQIKAGQMDFDIVIASPDTMRIVGTLGQILGPRGLMPNPKVGTVTPDVATAVKNAKAGQVQFRVDKAGIIHATIGRASFEPTALRSNLSALIEALQKAKPATSKGVYLRKIALSSTMGVGVRVDHATLAAQ
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: MYO13_ARATH
Sequence: MVFKVFSFVAFMACSTVKVGSIVWVQDPEEAWIDGEVVEVNGEDIKVQCTSGKTVVAKGSNTYPKDMEVPPSGVDDMTTLAYLHEPGVLQNLKSRYYIDEIYTYTGNILIAVNPFKQLPNLYNDHMMAQYKGAALGELSPHPFAVADAAYRQMINEGISQSILVSGESGAGKTETAKMLMKYLAKMGGRAVSDRRTVEDQVLESNPVLEAFGNAKTVKNNNSSRFGKFVEIQFDQRGRISGAAIRTYLLERSRVCQVSDPERNYHCFYMLCAAPPEDKRKLKLNDPTEFRYLNQSHCIKLDGVDDSKEYTKTREAMGIVGINLEEQEAIFRVVAAILHLGNIEFAIGEEPDSSVPTDESKKYLKIAAELFMCDEQALEDSLCKRIMVTPEETISRCLDPNSAALSRDALAKFVYSRLFDWIVNKINNSIGQDPDSKDMIGVLDIYGFESFKTNSFEQFCINLTNEKLQQHFTQHVLKMEQEEYTKEEIEWSQITFPDNRYVLELIEKKRGGIIALLDEACMFPRSTHKTFSQKLYETLKDNKYFSKPKLSRTDFTICHYAGDVTYQTEQFLEKNKDYVVAEHQALLGASRCTFIAGLFPPLVEDANKQSKFSSIASQFKQQLASLIEGLNTTEPHYIRCVKPNNLLKPSIFENQNSLQQLRCGGVMETIRVCRAGYPTRKHFDEFLDRFGILDSATLDKSSDEKAACKKLLETVGLNGFQIGKTKVFLKAGQMAELDDRRTEVLGRAACIIQWKFRSYLTRQSFIMLRNAAINIQAVYRGQVARYRFENLRREAAALKIQRALRIHLDRKRSYIEAVVTVQSGLRGMAARVVLRRKTKATTVIQSHCRRLRAELHYKKLKKAAITTQSAWRARLARKELRKLKTDARDTVVLQAAKSMLAEKVEELTWRLDLEKRMRVDMEVSKAQENAKLQLALEEIQLQFEETKVSLLKEVEAAKKTAAIVPVVKEVPVVDTVLMEKLTSENEKLKSLVTSLELKIDETEKKFEETKKISEERLKKALDAENKIDNLKTAMHNLEEKLKEVKLENNFLKESVLTTPVKTASGRFLSTPLKNLQNGLFTSEESQLSGAEFTTPPRIQESGSDTKSRGSHIDPQHEDVDALINSVTKNVGFSQGKPVAAFTIYKCLLHWKSFEAERTNVFDRLVQMIGSAIKDEDNDANLAYWLSNTSTLLFMLQQSLKSGGTGATPLRQSPSLVRWMTKGFRSPAAEAIRPVDAKDPALHFKQQLEAYVEKILGIIWDNLKKELNTVLALCIQAPKTFKGNALISITTANYWQDIIEGLDALLSTLKESFVPPVLIQKIFSQAFSLINVQVCNSLVTRPDNCSFINGEYLKSGLEKLEKWCCETKEEYAGSSWDELKHTRQAVGFLLIHKKYNISYDEIANDLCPNLQIQQHFKLCTLYKDEIYNTKSVSQDVIASMTGVMTDSSDFLLKEDSSNIISLSIDDLCSSMQDKDFAQVKPAEELLENPSFIFLH
What is the function of this protein?
Myosin heavy chain that is required for the cell cycle-regulated transport of various organelles and proteins for their segregation.  Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables (By similarity).
What are the official names of this protein?
Myosin-13, Myosin XI G, AtXIG.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. Plant myosin class XI subfamily.
Protein: NOMO3_HUMAN
Sequence: MLVGQGAGPLGPAVVTAAVVLLLSGVGPAHGSEDIVVGCGGFVKSDVEINYSLIEIKLYTKHGTLKYQTDCAPNNGYFMIPLYDKGDFILKIEPPLGWSFEPTTVELHVDGVSDICTKGGDINFVFTGFSVNGKVLSKGQPLGPAGVQVSLRNTGTEAKIQSTVTQPGGKFAFFKVLPGDYEILATHPTWALKEASTTVRVTNSNANAASPLIVAGYNVSGSVRSDGEPMKGVKFLLFSSLVTKEDVLGCNVSPVPGFQPQDESLVYLCYTVSREDGSFSFYSLPSGGYTVIPFYRGERITFDVAPSRLDFTVEHDSLKIEPVFHVMGFSVTGRVLNGPEGDGVPEAVVTLNNQIKVKTKADGSFRLENITTGTYTIHAQKEHLYFETVTIKIAPNTPQLADIVATGFSVCGQISIIRFPDTVKQMNKYKVVLSSQDKDKSLVTVETDAHGSFCFKANPGTYKVQVMVPEAETRAGLTLKPQTFPLTVTDRPVMDVAFVQFLASVSGKVSCLDTCGDLLVTLQSLSRQGEKRSLQLSGKVNAMTFTFDNVLPGKYKISIMHEDWCWKNKSLEVEVLEDDVSAVEFRQTGYMLRCSLSHAITLEFYQDGNGRENVGIYNLSKGVNRFCLSKPGVYKVTPRSCHRFEQAFYTYDTSSPSILTLTAIRHHVLGTITTDKMMDVTVTIKSSIDSEPALVLGPLKSVQELRREQQLAEIEARRQEREKNGNEEGEERMTKPPVQEMVDELQGPFSYDFSYWARSGEKITVTPSSKELLFYPPSMEAVVSGESCPGKLIEIHGKAGLFLEGQIHPELEGVEIVISEKGASSPLITVFTDDKGAYSVGPLHSDLEYTVTSQKEGYVLTAVEGTIGDFKAYALAGVSFEIKAEDDQPLPGVLLSLSGGLFRSNLLTQDNGILTFSNLSPGQYYFKPMMKEFRFEPSSQMIEVQEGQNLKITITGYRTAYSCYGTVSSLNGEPEQGVAMEAVGQNDCSIYGEDTVTDEEGKFRLRGLLPGCVYHVQLKAEGNDHIERALPHHRVIEVGNNDIDDVNIIVFRQINQFDLSGNVITSSEYLPTLWVKLYKSENLDNPIQTVSLGQSLFFHFPPLLRDGENYVVLLDSTLPRSQYDYILPQVSFTAVGYHKHITLIFNPTRKLPEQDIAQGSYIALPLTLLVLLAGYNHDKLIPLLLQLTSRLQGVGALGQAASDNSGPEDAKRQAKKQKTRRT
What is the function of this protein?
Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes (PubMed:36261522, PubMed:32820719).  The MPT complex takes over after the SEC61 complex: following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex, the MPT complex occludes the lateral gate of the SEC61 complex to promote insertion of subsequent transmembrane regions (PubMed:36261522).
What are the official names of this protein?
BOS complex subunit NOMO3, Nodal modulator 3, pM5 protein 3.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: SCPA_STRT1
Sequence: MDIKLKDFEGPLDLLLHLVSKYEVDIYDVPIVEVIEQYLAYLATLQAMKLEVAGEYMLMASQLMLIKSRKLLPTVVEDEPEVDDPELELLSQLEEYAHFKAASQVLAKKHEVRAQYFSKPKVELVYEDVTLNQDKTIQDIFLAFSKIMAEKQEEIRRRHTTIARDDYKIEDMMLIIEEAFSAKNKLFLDELFSDAKDMNQVITLFLATLELIKIHRISVQQETIFGTITLRKEWTNE
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein A.
What is the protein family that this protein belongs to?
Belongs to the ScpA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: RL11_GEOMG
Sequence: MAKKITGYIKLQIPAGKANPSPPIGPALGQHGVNIMEFCKAFNAKTQGDEGTITPVVITVYADRSFSFITKVPPMSVLIKKAVGIESGSSVPNKNKVGTLTAEQVKEIAVKKMPDMNAASLEAAMRTVEGTARSMGVEIV
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RMUC_RICFE
Sequence: MPYLLPITAAALLILLALIIWFYVKTKTFKTQLQFLSEQNLEISNNNQLLNQEKIGCLQKIEQLKCKVEYQEQTIKDSEKIREESFSSAKAALFDLGKDLSKQLIEIHKMENNAARELAEKNIATASGKFNSEFERLITMVGALNKDIEQSKGTVDLIKQSLLSPIGAGLLAEITLENILKSSGLRPNLDFIMQYGLTTTDSGKLRPDALIFLPSGNLMVIDSKASKFLVDEQDNSGNLSKTMNYHLKSLANKDYAENILTNLNKKDQNFNNVITLMFLPTEQAVEKVIAADPEFLQKAWSCNIFPVGPAGLMNMLSFAKFQITDHRRSENYKVIIEEVRKLLSSIGTMADYSQKIGNNLHNMVTNYDKFAASFNRNFMSRVKNIHKLGIDSGNKAMPAALERYQIVSSKSEIIEVEAENPPQIEEKL
What is the function of this protein?
Involved in DNA recombination.
What are the official names of this protein?
DNA recombination protein RmuC homolog.
What is the protein family that this protein belongs to?
Belongs to the RmuC family.
Protein: RECR_DESAP
Sequence: MQYSRSVGRLIEELARLPGIGPKTAQRLAFHLVTAPREAAESLSRAILEARDKLVFCRVCANIADENPCGICRDQNRDHGLICVVERPRDVLAVEKAHGYRGLYHVLNGSLSPLQGVGPEELNIAALVTRVREGTVREVIVATNATVEGEATALYLARLLRPLNVRVTRLAFGLPVGSDLEYADGRTLARAIEGRREV
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: PURE_ALIF1
Sequence: MKVGIIMGSKSDWPTMKLAAEMLDRFNVPYETKVVSAHRTPQLLADYATQAKDRGIKVIIAGAGGAAHLPGMAAAFTSVPVLGVPVQSRALKGMDSLLSIVQMPKGIAVGTLAIGEAGAANAGILAAQIIGTSNEEVMAAVEAFRKEQTEMVLENPDPSED
What is the function of this protein?
Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
What are the official names of this protein?
N5-carboxyaminoimidazole ribonucleotide mutase, N5-CAIR mutase, 5-(carboxyamino)imidazole ribonucleotide mutase.
What is the protein family that this protein belongs to?
Belongs to the AIR carboxylase family. Class I subfamily.