PharMolix/UniProtQA huggingface dataset:
Protein: AMT52_ALTAL
Sequence: MASYGFPLTASSLVDWTSLTFSPIEVNGHIQCTYSPEVAEWGAPHFVKDPYLRVHGLAPALNYGQQIFEGMKAFRTPTGSIRLFRPKMNAVRFAHSASFVAIPPVPEALFLRAVHLAVGLNSEFVPPYDSRGSALYIRPIAFASSATANLAPADHFTFCVFVMPVAPLSTGAGQGLRALVVEDVDRAAPKGTGSAKVGGNYAPIVTTMQRAKADGYGLTLHLDSATHTMVDEFSASGFIGVRVDAGKTTMVVPDSPTILRSITVDSMCRIAESFGWQVQRRAVSFTELAELSEAFAVGTAFILTPVRAITRPCTHTCIEYTADYRSSASAYTRLLETLQGIQQGWLDDAWGWTEEVQDPSSDEFITDTVQARR
What is the function of this protein?
Transaminase; part of the gene clusters that mediate the biosynthesis of AM-toxins, host-selective toxins (HSTs) causing Alternaria blotch on apple, a worldwide distributed disease (By similarity).  AM-toxins are cyclic depsipeptides containing the 3 residues 2-hydroxy-isovaleric acid (2-HIV), dehydroalanine, L-alanine which are common for all 3 AM-toxins I to III.  The fourth precursor is L-alpha-amino-methoxyphenyl-valeric acid (L-Amv) for AM-toxin I, L-alpha-amino-phenyl-valeric acid (L-Apv) for AM-toxin II, and L-alpha-amino-hydroxyphenyl-valeric acid (L-Ahv) for AM-toxin III (Probable).  AM-toxins have two target sites for affecting susceptible apple cells; they cause invagination of the plasma membrane and electrolyte loss and chloroplast disorganization (PubMed:22846083).  The non-ribosomal peptide synthetase AMT1 contains 4 catalytic modules and is responsible for activation of each residue in AM-toxin (PubMed:10875335).  The aldo-keto reductase AMT2 catalyzes the conversion of 2-keto-isovaleric acid (2-KIV) to 2-hydroxy-isovaleric acid (2-HIV), one of the precursor residues incorporated by AMT1 during AM-toxin biosynthesis, by reduction of its ketone to an alcohol (PubMed:15066029).  The cytochrome P450 monooxygenase AMT3 and the thioesterase AMT4 are also important for AM-toxin production, but their exact function within the AM-toxin biosynthesis are not known yet (PubMed:17990954).  Up to 21 proteins (including AMT1 to AMT4) are predicted to be involved in AM-toxin biosynthesis since their expression ishighly up-regulated in AM-toxin-producing cultures (PubMed:17990954).
What are the official names of this protein?
Transaminase AMT5-2, AM-toxin biosynthesis protein 5-2.
What is the protein family that this protein belongs to?
Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
Protein: YPDE_ECOLI
Sequence: MDLSLLKALSEADAIASSEQEVRQILLEEADRLQKEVRFDGLGSVLIRLNESTGPKVMICAHMDEVGFMVRSISREGAIDVLPVGNVRMAARQLQPVRITTREECKIPGLLDGDRQGNDVSAMRVDIGARSYDEVMQAGIRPGDRVTFDTTFQVLPHQRVMGKAFDDRLGCYLLVTLLRELHDAELPAEVWLVASSSEEVGLRGGQTATRAVSPDVAIVLDTACWAKNFDYGAANHRQIGNGPMLVLSDKSLIAPPKLTAWVETVAAEIGVPLQADMFSNGGTDGGAVHLTGTGVPTVVMGPATRHGHCAASIADCRDILQMQQLLSALIQRLTRETVVQLTDFR
What is the function of this protein?
Has a broad aminopeptidase activity on non-blocked peptides by progressively cleaving amino acids off the peptide substrate.  Aminopeptidase activity stops at the residue before the first proline in the peptide.  Cannot cleave when proline is the first N-terminal residue.
What are the official names of this protein?
Aminopeptidase YpdE.
What is the protein family that this protein belongs to?
Belongs to the peptidase M42 family.
Protein: S10A6_RAT
Sequence: MACPLDQAIGLLVAIFHKYSGKEGDKHTLSKKELKELIQKELTIGAKLQDAEIARLMDDLDRNKDQEVNFQEYVAFLGALALIYNEALK
What is the function of this protein?
May function as calcium sensor and modulator, contributing to cellular calcium signaling.  May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility.  Binds 2 calcium ions.  Calcium binding is cooperative (By similarity).
What are the official names of this protein?
Protein S100-A6, Calcyclin, Prolactin receptor-associated protein, S100 calcium-binding protein A6.
What is the protein family that this protein belongs to?
Belongs to the S-100 family.
What are the subcellular locations of this protein?
Nucleus envelope. Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TYB12_LATJA
Sequence: MSDKPDISEVTSFDKTKLKKTETQEKNPLPSKETIEQEKAAATS
What is the function of this protein?
Plays an important role in the organization of the cytoskeleton.  Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization (By similarity).
What are the official names of this protein?
Thymosin beta-12.
What is the protein family that this protein belongs to?
Belongs to the thymosin beta family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: YP257_YEAST
Sequence: MTAHANERISDVSPSARGSSSESKYDKLCRVLFFIAITKSSFTPEHILYKHSIFTDKPILADIVTFMYAAFVSIGWFLIWGERAYRTQEMGQPPMYSNINYHLLSFKKRHPKKFTCALWLVFFLAYTVLTVLIWLVQLIFRKGNVFQMLLQLIILDIAIALVNVAIAFTFEIYLSQKAAIEIRDEGLNNLDTA
What is the function of this protein?
May be required for cell cycle progression.
What are the official names of this protein?
Uncharacterized membrane protein YPL257W.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: BIOF_ECOL5
Sequence: MIWQEKIDAALDARRVADALRRRYPVAQGAGRWLVADDCQYLNFSSNDYLGLSHHPQIIRAWQQGAEQFGVGSGGSGHVSGYSVAHQVLEEELAEWLGYSRALLFISGFAANQAVIAAMMAKEDRIVADRLSHASLLEAASLSPSPLRRFAHNDVTHLARLLASPCPGQQLVVTEGVFSMDGDSAPLEEIQQVTQQHDGWLMVDDAHGTGVIGEQGRGSCWLQKVKPELLVVTFGKGFGVSGAAVLCSNTVADYLLQFARHLIYSTSMPPAQAQALRASLAVIRSDEGDARREKLAALITRFRAGVQDLPFTLADSWSAIQPLIVGDNSRALQLAEKLRQQGCWVTAIRPPTVPAGTARLRLTLTAAHEMQDIDRLLEVLHGNG
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: 2SSE_BRANA
Sequence: MANKLFLVSATLALFFLLTNASVYRTVVEVDEDDATNPAGPFRIPKCRKEFQQAQHLRACQQWLHKQAMQPGGGSGPSWTLDGEFDFEDDVENQQQGPQQRPPPPQQCCNELHQEEPLCVCPTLKGASKAVRQQVRQQQGQQMQGQQMQQVISRVYQTATHLPRVCNIRQVSICPFQKTMPGPGFY
What is the function of this protein?
The small, basic, water-soluble napins are one of the two major kinds of storage proteins synthesized in the seed during its maturation.
What are the official names of this protein?
Napin embryo-specific, 1.7S seed storage protein.
What is the protein family that this protein belongs to?
Belongs to the 2S seed storage albumins family.
Protein: HYPA_THEGJ
Sequence: MHEWALADAIVRTVLDYAQREGAKRVKAVRVVLGELQDVAEDIVKFAMEQMFAGTIAEGAEIIFEEEEAVFKCRNCGHTWKLKEVKDRFDERIKEDIHFIPEVVHAFLACPKCGSHDFEVVQGRGVYVAGIMIEKEGEA
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: GWD1_CITRE
Sequence: MSNSIGRNVLHQSLLCSTVFEHQSNRHSSGIPANSLFQAVSINQPAGASAARKSPLSTKFYGTSLNARPKMAMGRHRPVLITPRAVLAVDSASELAGKFNLEGNVELQITVGAPTPGSLTQVNIEISYSSNSLLLHWGAIRDKKEKWVLPSRPPDGTKILKNRALRTPFVSSGSKSLVKLEIDDPAIEAVEFLILDEAQNKWFKNNGANFHVKLPSERSLIQNVSVPEDLVQTQAYLRWERKGKQIYTPEQEKEEYEAARTELLEEIVRGTSVEDLRAKLTNKNDRQEIKESSSHGTKNAIPDDLVQIQSYIRWERAGKPNYSADQQLREFEEARKELQSELEKGISLDEIWKKITKGEIQTKVSDQLKTKKYFRTERIQRKQRDFMQILNKHVAEPTEKKNISVEPKALTPVELFVGATEEQEGDSILNKKIYKLAGKELLVLVHKPGGKTKIHLATDGKEPLILHWALSKKAGEWLAPPPSVLPAGSVLLSGSVETTFTTSSLADLPYQVQSIEIEIEEEGYVGMPSVLQSGGNWIKNKGSDFYVDFSYESKQVQQDFGDGKGTAKALLEKIAGLEIEAQKSFMHRFNIAADLIQEAKEAGELGFAGILVWMRFMATRQLIWNKNYNVKPREISKAQDRLTDLLQNVYISNPEYREIVRMILSTVGRGGEGDVGQRIRDEILVIQRNNNCKGGMMEEWHQKLHNNTSPDDVIICQALIDYIKSDFDISAYWKTLNDNGITKERLLSYDRAIHSEPNFRRDQKDGLLRDLGNYMRTLKAVHSGADLESAITNCLGYRSEGQGFMVGVQINPIPNLPSGFPELLQFVSEHVEDRNVEALLEGLLEARQEIRPLLCKHNDRLKDLLFLDIALESSVRTAIEKGYEELNEAGPEKIMYFVSLILENLALSLDDNEDLIYCLKGWSNALSMSKSKSDNWALFAKSVLDRTRLALAGKADWYQKVLQPSAEYLGTLLSVDKWAVDIFTEEMIRAGSAAALSLLLNRLDPVLRKTASLGSWQVISPVEVFGYVAVVDELLAVQDKSYDQPTILLARRVKGEEEIPHGTVAVLTADMPDVLSHVSVRARNCKVCFATCFDPNILADLQSNEGKMLHLKPTSADIAYSVVEGSELQDSSSANLKEEDGPSSSVALVKKQFAGRYAITSDEFTGELVGAKSRNIAYLKGKVPSWIGIPTSVALPFGVFEKVLSDDINQAVAEKLQILKQKLGEEDHSALREIRETVLQMKAPNQLVQELKTEMKSSGMPWPGDEGEQRWEQAWMAIKKVWASKWNERAFFSTRRVKLDHEYLCMAVLVQEIINADYAFVIHTTNPSSGDSSEIYAEVVKGLGETLVGAYPGRALSFVCKKNDLKSPRVLGYPSKPIGLFIRRSIIFRSDSNGEDLEGYAGAGLYDSVPMDEAEKVVLDYSSDHLITDGHFQQSILSSIARAGCEIEELFGSAQDIEGVVRDGKIYVVQTRPQM
What is the function of this protein?
Mediates the incorporation of phosphate into starch-like alpha-glucan, mostly at the C-6 position of glucose units.  Acts as an overall regulator of starch mobilization.  Required for starch degradation, suggesting that the phosphate content of starch regulates its degradability (By similarity).
What are the official names of this protein?
Alpha-glucan water dikinase, chloroplastic, Starch-related protein R1.
What is the protein family that this protein belongs to?
Belongs to the PEP-utilizing enzyme family.
What are the subcellular locations of this protein?
Plastid, chloroplast. Note=Starch granules.
Protein: NOIL_ELAOL
Sequence: MAQPAHVPKFGNWDGENISYTTYFETVHRDKGDGSKIFNPNDPEENPQAFYPRTVAQDHQHSEKHHNDTSTDYHVVKQHRRKHHRREDREFHRYVEAPRPHRSPFQGVDMDSHRSRNHGTSATMSSSVKRNSDNWLPQHQHHRRTNKDLAEGKSWLFTTTTASSYTKSRKLSRECSSTTQSSISAKNLVPGDETRSPISWRVFQSYLTKLKEQKQIAATKIGQHLNLR
What are the official names of this protein?
NOI-like protein.
What is the protein family that this protein belongs to?
Belongs to the RIN4 family.
Protein: HSLU_OLEA2
Sequence: MSVLTPREIVSELDKYIIGQEQAKRMVAVALRNRWRRQQLEPAIRDEVAPKNIIMMGPTGVGKTEIARRLARLSSSPFLKVEATKFTEVGYVGRDVESMIRDLMEISVNLVREEERDSVKTRAEAAAEERLLDLLLPSSPAVNTSFDTPQTPAGGAENTRNKLRTLWREGRLDHREVEMEVEMQSGPQMDVMTMPGMEDIGSQFKDMFSKAFPPKRKRRRMKVGDAYAILLQEESERLIDHEKVIELARERAEQTGIIFLDEIDKIASSQQGGKTADISREGVQRDLLPIVEGSAVNTKYGIIHTDHILFIGAGAFHYSKPSDLIPELQGRFPLRVELTALGSKEFLRILTEPKNALTVQYKALLATEGVQIEYTEDALEAVADFAQEANQETENIGARRLYTIMEKILADLSFEAPDKSGERIVIDREYVRQHLADITANRDLTRYIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPE_BORPE
Sequence: MTASAVLDLVKDLIARPSVTPDDVDCQMLLAQRLERIGFQCETIARGGVTNLWARRGAGAPLTVFAGHTDVVPPGPRDKWDSDPFVPTERDGFLYGRGAADMKSSIAAFVVAAEEFVAVHPEHPGSIALLITSDEEGPAVDGTVIVCDELRQRGEQLDYCIVGEPTSTEALGDVCKNGRRGSLSGRLLVKGVQGHVAYPHLARNPVHQLAPALTELVAIEWDQGNEYFPPTTFQVSNLHAGTGATNVVPGEAVALFNFRFSTASTPGQLKARVHEVLDRHGLEYQLDWELGGEPFLTPRGSLTDALVSAIQAETGLQAELSTTGGTSDGRFIARICPQVIEFGPCNATIHKVNERIELSSLAPLKNIYRRTLENLLLAD
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: Y2098_RHILO
Sequence: MGSTSDKASGLANEAVGKAKEGVGKAVGNDRLRAEGAAQEAKGKVQKAVGDAKSAVKDATNKTAAAINKNL
What are the official names of this protein?
UPF0337 protein mlr2098.
What is the protein family that this protein belongs to?
Belongs to the UPF0337 (CsbD) family.
Protein: SECB_PSEA6
Sequence: MAEENQTTPADAAQAAQGPQFAIQRIYTKDISFETPNSPAIFQKEWKPEVQLDLDTRSALIEENVYEIVLAVTVTAMLGEETAFLCEVQQAGIFAIGEMPEQNKAHMLGSFCPNTLFPYARETISNLVNRGTFPPLNLAPVNFDAIFAAYMQKRAAQQAQEQAPTQLDA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPS06_ARATH
Sequence: MEAITKYGSYFNVRFLSRLCWRLNLSSSYHYPLLKSSLSFSRFQSPKKLCLVRATTNPTDDNSTTRSFTPHPPSLWGHHFLSASVNQTEMDDLWRQIEALKPIVNAMLLPCNGADAKKITCFIHTLVSLGVSYHFEEKIVEFLKDAFENIEDMIIDCKEDDLYTVSIIFRVFRLYGHYITPDIFNRFKGDDGNFKKCLNDDVRGMLSFYEASHFGTTTEDILEEAMSFTQKHLELFLVGEKAKHYPHITKLIQAALYIPQNFNLEILVAREYIDFYELETDHNEMLLKLAKLNFRFLQLQYIQDLKTLTTWWKELDLVSKIPVYFRERLAEPYFWATGIYYEPQYSAARIMLAKSIILVDIVDNTFDVYGTIDEVKSLVQAIERWDSDAVDVLPDYLKVVFRTTFDLFKELEEYVSSEARSFTMQYAYEQLRILMKGYLQEAEWSNRGHLPSHEEYIEVGVASTAGEVLLAMTFIPMGDAAGVGVYEWLRSRPKLTHALFVKSRLRDDIATYKEEMKRGDVCNGINCYTKQHKVSEEEACIEFEKKTNHMSKVMNEEFLKAAKFIPLHILRPVLNYGRLADVCYKYGDGYTFAGEKIKDYITSLYVDLITL
What is the function of this protein?
Involved in terpene biosynthesis in roots.  Possesses sesquiterpene (C15) synthase activity and diterpene (C20) synthase activity in vitro.  Possesses dolabella-3,7-dien-18-ol synthase activity in vitro.  Catalyzes the formation of dolabella-3,7-dien-18-ol from geranylgeranyl diphosphate.
What are the official names of this protein?
Dolabella-3,7-dien-18-ol synthase TPS06, Terpenoid synthase 6, AtTPS06.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsa subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YEGX_ECOL6
Sequence: MQLRITSRKKFTVLLCALGLISIVAIYPRQTVNFFYSTAIQIKDYIHFYGYRPVKSFAIRIPASYTIHGIDVSRWQERIDWQRVAKMRDNGIRLQFAFIKATEGEKLVDPYFSRNWQLSRENGLLRGAYHYFSPSVSASVQARLFLQTVDFSQGDFPAVLDVEERGKLSAKELRKRVSQWLKMVEKRTGKKPIIYSGAVFYHTNLAGYFNEYPWWVAHYYQRRPDNDGMAWRFWQHSDRGQVDGINGPVDFNVFNGTVEELQGFVDGIKETP
What are the official names of this protein?
Uncharacterized protein YegX.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 25 family.
Protein: TEX29_MOUSE
Sequence: MKDTKEIKRSPPHLLKKFAVCDIPLYDICDYNVTRERCRSLDCCFYRGVCYEKAVPIYVQVFFTLIWFVAGAFIIAVIYRVIQGTKKEKKPLLPEDSQVEILKSPTPELIPEPIPEPIPEPIPEPIREPPPPVKKTESPIEAGCCLWMKSKPAKDQPQKETAAPEPPSNPEVKKVNSGSAVPQAAP
What are the official names of this protein?
Testis-expressed protein 29.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PDXA_PSEA6
Sequence: MTIKLAITPGEPAGVGPDLIITLAQQQWQAMLVVFANAELMRTRANELNIPLTLLPYDASRTDIQPAGSLYIVDIPLQDEVIAGKLNPTNSQYVLDTLHQACQMNLNGEFQALVTGPVHKGVINEAGIPFSGHTEFFAQQSNTPEVVMMLATEGLRVTLATTHIPVTAVSAAITQPKLDNVIRIIDHDLRTKFGIAKPHIFVCGLNPHAGEDGHIGREEIDTIIPALNALRQEGITLTGPLPADTIFNPKYLQQADTVLAMYHDQGLPVLKYKGFSQAVNITLGLPFIRTSVDHGTALDLAATGQADVGSFSIAIKEAISLAKSTQ
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MS2A_DROME
Sequence: MNQILLCSPILLLLFTVASCDSEQQLDSAMHLKSDSTKSASLKNVAPKNDETQAKIAKDDVALKDAKKGDYIMDIDISDLPLDDYPINRSKSLKSSSIDLNNIPFNKGLDDFPAKEKNQGSNQSALKALQQRLLTEQNNSLLLRNHSIYLMKEIEARKTDIIKVRQLNLDLELELNTVNRRLLELNGQLQNTRKSTKPCKKRSSKDSAPPAANQFQEANVRNTYRNKYLTLLKELSQKINNEIAKVATDVPTETNPSQGNLPTL
What is the function of this protein?
Male seminal peptide which is able to enhance ovulation in female Drosophila.
What are the official names of this protein?
Accessory gland-specific peptide 26Aa, Male accessory gland secretory protein 355A.
What are the subcellular locations of this protein?
Secreted. Cytoplasm. Note=In 1 day old virgin males, secreted into the cytoplasm of accessory gland cells (PubMed:2257979). In 5 day old males it localizes to cytoplasmic vesicles of the secondary cells (PubMed:2257979).
Protein: PUR9_MYCLB
Sequence: MSSDGERDMARKPIRRALISVYDKTGLIDLAQGLNAAGVDIVSTGSTAKAIADQGIAVTPVEELTGFPEVLDGRVKTLHPRVHAGLLADLRKPEHAAALEQLGIEAFELVVVNLYPFSQTVKSGATVDECVEQIDIGGSSMVRAAAKNHPSVAVVTDPLGYVGVLAAVQGGGFTLAERKMLASMAFQHIAEYEIAVASWMQSTLAPEQPPTAFPQWFGRSWRRSAILRYGENPHQQAALYSDPSACPGLAQAEQLHGKNMSYNNFTDADAAWRAAFDHEQSCVAIIKHANPCGIAISSLSVADAHRKAHECDPLSAYGGVIAANTEVSLEMAEYVSTIFTEVIVAPSYAPGAVDVLSCKKNVRVLVASAPLRGGSELRPVSGGLLIQQPDQLDTAGDNPANWTLATGSPAGPATLTDLVFAWRACRAVKSNAIVIAADGATIGVGMGQVNRVDAARLAVERGGDRVRGAVVASDAFFPFADGLQTLAAAGVTAIVHPGGSVRDAEVTAAATKAGVTLYLTGVRHFVH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: RPOC1_PROSC
Sequence: EVTKPETINYRTLKPEMDGLFCERIFGPAKDWECHCGKYKRVRYKGIVCERCGVEVTESKVRRHRMGYIKLAAPVTHVWYLKGIPSYMSIILDMPLRDVEQIVYFNAYVVLDPGNAQNLSYKQLLTEDQWLEIEEQIYGEDSELLGIEVGIGAEAVKRLLEEVDKTSEAEKLRSEIANCKGQKRAKLIKRLRVIDNFVATGSR
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit gamma, RNAP subunit gamma, RNA polymerase subunit gamma, Transcriptase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
Protein: EZRA_STAAS
Sequence: MVLYIILAIIVIILIAVGVLFYLRSNKRQIIEKAIERKNEIETLPFDQNLAQLSKLNLKGETKTKYDAMKKDNVESTNKYLAPVEEKIHNAEALLDKFSFNASQSEIDDANELMDSYEQSYQQQLEDVNEIIALYKDNDELYDKCKVDYREMKRDVLANRHQFGEAASLLETEIEKFEPRLEQYEVLKADGNYVQAHNHIAALNEQMKQLRSYMEEIPELIRETQKELPGQFQDLKYGCRDLKVEGYDLDHVKVDSTLQSLKTELSFVEPLISRLELEEANDKLANINDKLDDMYDLIEHEVKAKNDVEETKDIITDNLFKAKDMNYTLQTEIEYVRENYYINESDAQSVRQFENEIQSLISVYDDILKEMSKSAVRYSEVQDNLQYLEDHVTVINDKQEKLQNHLIQLREDEAEAEDNLLRVQSKKEEVYRRLLASNLTSVPERFIIMKNEIDHEVRDVNEQFSERPIHVKQLKDKVSKIVIQMNTFEDEANDVLVNAVYAEKLIQYGNRYRKDYSNVDKSLNEAERLFKNNRYKRAIEIAEQALESVEPGVTKHIEEEVIKQ
What is the function of this protein?
Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation.  Inhibits FtsZ ring formation at polar sites.  Interacts either with FtsZ or with one of its binding partners to promote depolymerization.
What are the official names of this protein?
Septation ring formation regulator EzrA.
What is the protein family that this protein belongs to?
Belongs to the EzrA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=Colocalized with FtsZ to the nascent septal site.
Protein: TRPC_WOLSU
Sequence: MILDEIVQKTREELENRKKEYPLEWLGRSLAYNPYMPRDVKKALQSTPERPYRIIAEVKKASPSKGIIREDFEPVSIAKAYELGGADALSILTEPHYFKGNLEYITQVRRYVPMPLLRKDFIIDSYQILEALVYGADFILLIAAALKASELKELLEYARHLGLEVLVEVHNKEDLTKAIWAGADIVGINHRDLQTFEMHMNLCHELIPLIPQGKIIVAESGLSSPKTLEELHGIGVDAFLIGEHFMRQKDVTQALLDIYPLNKK
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: PAG62_BUBBU
Sequence: RGSXLTHLPLRNISD
What are the official names of this protein?
Pregnancy-associated glycoprotein 62, PAG 62, Pregnancy-associated glycoprotein 58F, Pregnancy-associated glycoprotein 65E, Pregnancy-associated glycoprotein 73I.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: OIAK_PARG4
Sequence: MNGTEPAEPTNGTNATAWPAGLLLAYYGDDFTGSTDAMEAMQAAGVPTVLCLQKPTPELLARFPEVRCVGMAGSSRGRSSAWMDDELPDVLASLAALGAPILQYKVCSTFDSSPEVGSIGRAIDIGVRHMPGNWSPMVIGAPRLKRYQMFGNLFAAVDGVGYRLDRHPTMSRHPVTPMNEADLRLHLARQTARRIELIDMLELRGADVATRVRALCAPDMPVVLIDVLDEETLAEAGRLVWEQRGEGIFTASSSGLQYALAAHWRARGLLPPTPSLPAADPVQAIAAVSGSCSPVTAAQIGWARAHGFHTERLDLPRALDSRDGAAEIERVVTAATQALTRGISVIVHSAEGPDDPAVTGFDAIASAAGFARHDAARKVGRALAEVMRRLLDSVELTRVVVAGGDSSGEVASVLGIDALSVMAGLVPGAPLCRAWSAEPRRDGLQIVLKGGQIGDATFFGMVREGRLAGA
What is the function of this protein?
Involved in catabolism of D-apiose.  Catalyzes the phosphorylation of 3-oxo-isoapionate to 3-oxo-isoapionate 4-phosphate.
What are the official names of this protein?
3-oxo-isoapionate kinase.
What is the protein family that this protein belongs to?
Belongs to the four-carbon acid sugar kinase family.
Protein: DIRLP_PINHA
Sequence: DISVVGGTGDFLMAR
What are the official names of this protein?
Dirigent-like protein.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: RS18_THEP1
Sequence: MAYKRKRKKVKKCRLCEMELDYVDYKDTRLLSEFLTDKGKIIPKRLTGNCSKHQRMVKVAIKRARQMGLLPYLKI
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: TGM2_HUMAN
Sequence: MAEELVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFSVVTGPAPSQEAGTKARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLEASTGYQGSSFVLGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPWNFGQFEDGILDICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGRWDNNYGDGVSPMSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTNYNSAHDQNSNLLIEYFRNEFGEIQGDKSEMIWNFHCWVESWMTRPDLQPGYEGWQALDPTPQEKSEGTYCCGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQDDGSVHKSINRSLIVGLKISTKSVGRDEREDITHTYKYPEGSSEEREAFTRANHLNKLAEKEETGMAMRIRVGQSMNMGSDFDVFAHITNNTAEEYVCRLLLCARTVSYNGILGPECGTKYLLNLNLEPFSEKSVPLCILYEKYRDCLTESNLIKVRALLVEPVINSYLLAERDLYLENPEIKIRILGEPKQKRKLVAEVSLQNPLPVALEGCTFTVEGAGLTEEQKTVEIPDPVEAGEEVKVRMDLLPLHMGLHKLVVNFESDKLKAVKGFRNVIIGPA
What is the function of this protein?
Has cytotoxic activity: is able to induce apoptosis independently of its acyltransferase activity.
What are the official names of this protein?
Protein-glutamine gamma-glutamyltransferase 2, Erythrocyte transglutaminase, Heart G alpha(h), hhG alpha(h), Isopeptidase TGM2, Protein G alpha(h), G(h), Protein-glutamine deamidase TGM2, Protein-glutamine dopaminyltransferase TGM2, Protein-glutamine histaminyltransferase TGM2, Protein-glutamine noradrenalinyltransferase TGM2, Protein-glutamine serotonyltransferase TGM2, Tissue transglutaminase, tTG, tTgase, Transglutaminase C, TG(C), TGC, TGase C, Transglutaminase H, TGase H, Transglutaminase II, TGase II, Transglutaminase-2, TG2, TGase-2, hTG2.
What is the protein family that this protein belongs to?
Belongs to the transglutaminase superfamily. Transglutaminase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Chromosome. Secreted, extracellular space, extracellular matrix. Cell membrane. Mitochondrion. Note=Mainly localizes to the cytosol (PubMed:9575137). Present at much lower level in the nucleus and chromatin (PubMed:9575137). Also secreted via a non-classical secretion pathway to the extracellular matrix (PubMed:27270573). SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm, perinuclear region.
Protein: LIN52_MOUSE
Sequence: MGWKMASPTDGTDLEASLLSFEKLDRASPDLWPEQLPGVAEFAASFKSPITSSPPKWMAEIERDDIDMLKELGSLTTANLMEKVRGLQNLAYQLGLDESREMTRGKFLNILEKPKK
What are the official names of this protein?
Protein lin-52 homolog.
What is the protein family that this protein belongs to?
Belongs to the lin-52 family.