PharMolix/UniProtQA huggingface dataset:
Protein: PRGR_RAT
Sequence: MTELQAKDPRTLHTSGAAPSPTHVGSPLLARLDPDPFQGSQHSDASSVVSPIPISLDRLLFSRSCQAQELPDEKTQNQQSLSDVEGAFSGVEASRRRSRNPRAPEKDSRLLDSVLDTLLAPSGPEQSQTSPPACEAITSWCLFGPELPEDPRSVPATKGLLSPLMSRPESKAGDSSGTGAGQKVLPKAVSPPRQLLLPTSGSAHWPGAGVKPSQQPATVEVEEDGGLETEGSAGPLLKSKPRALEGMCSGGGVTANAPGAAPGGVTLVPKEDSRFSAPRVSLEQDAPVAPGRSPLATTVVDFIHVPILPLNHALLAARTRQLLEGDSYDGGAAAQVPFAPPRGSPSAPSPPVPCGDFPDCTYPPEGDPKEDGFPVYGEFQPPGLKIKEEEEGTEAASRSPRPYLLAGASAATFPDFPLPPRPPRAPPSRPGEAAVAAPSAAVSPVSSSGSALECILYKAEGAPPTQGSFAPLPCKPPAASSCLLPRDSLPAAPTSSAAPAIYPPLGLNGLPQLGYQAAVLKDSLPQVYPPYLNYLRPDSEASQSPQYGFDSLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVMRALDGVALPQSVAFPNESQTLGQRITFSPNQEIQLVPPLINLLMSIEPDVVYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKELSFYSLCLTMWQIPQEFVKLQVTHEEFLCMKVLLLLNTIPLEGLRSQSQFEEMRSSYIRELIKAIGLRQKGVVPSSQRFYQLTKLLDSLHDLVKQLHLYCLNTFIQSRALAVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK
What is the function of this protein?
Transcriptional activator of several progesteron-dependent promoters in a variety of cell types.  Involved in activation of SRC-dependent MAPK signaling on hormone stimulation.
What are the official names of this protein?
Progesterone receptor, PR, Nuclear receptor subfamily 3 group C member 3.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Nucleoplasmic shuttling is both hormone- and cell cycle-dependent. On hormone stimulation, retained in the cytoplasm in the G(1) and G(2)/M phases (By similarity).
Protein: COQ2_DROME
Sequence: MYALRHLRLQSARHFRSSYAAAATTKHMLPRQPARVLIGDWSTWDKSRLQDVCSRSSSTATEPVKQQTPLQELVSAAKPYAQLMRIDRPIGTYLLFWPCAWSIALSADAGCWPDLTMLGLFGTGALIMRGAGCTINDLWDKDIDAKVERTRLRPLASGQISQFDAIVFLSAQLSLGLLVLVQLNWQSILLGASSLGLVITYPLMKRVTYWPQLVLGMAFNWGALLGWCATQGSVNLAACLPLYLSGVCWTIVYDTIYAHQDKLDDLQIGVKSTALRFGENTKVWLSGFTAAMLTGLSAAGWACDQTVPYYAAVGVVGAHLVQQIYSLNIDNPSDCAKKFISNHQVGLILFLGIVLGTLLKSDESKKQRQSSLTTSTASSYVPALPQKPEVLS
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
What are the official names of this protein?
4-hydroxybenzoate polyprenyltransferase, mitochondrial, 4-HB polyprenyltransferase, Coenzyme Q biosynthesis protein 2, Para-hydroxybenzoate--polyprenyltransferase, PHB:PPT, PHB:polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein; Matrix side.
Protein: ADM1A_MOUSE
Sequence: MSVAAAGRGFASSLSSPQIRRIALKEAKLTPHIWAALHWNLGLRLVPSVRVGILVLLIFLPSTFCDIGSVYNSSYETVIPERLPGKGGKDPGGKVSYMLLMQGQKQLLHLEVKGHYPENNFPVYSYHNGILRQEMPLLSQDCHYEGYMEGVPGSFVSVNICSGLRGVLIKEETSYGIEPMLSSKNFEHVLYTMEHQPVVSCSVTPKDSPGDTSHPPRSRKPDDLLVLTDWWSHTKYVEMFVVVNHQRFQMWGSNINETVQAVMDIIALANSFTRGINTEVVLVGLEIWTEGDPIEVPVDLQTTLRNFNFWRQEKLVGRVRHDVAHLIVGHRPGENEGQAFLRGACSGEFAAAVEAFHHEDVLLFAALMAHELGHNLGIQHDHPTCTCGPKHFCLMGEKIGKDSGFSNCSSDHFLRFLHDHRGACLLDEPGRQSRMRRAANCGNGVVEDLEECDCGSDCDSHPCCSPTCTLKEGAQCSEGLCCYNCTFKKKGSLCRPAEDVCDLPEYCDGSTQECPANSYMQDGTQCDRIYYCLGGWCKNPDKQCSRIYGYPARSAPEECYISVNTKANRFGNCGHPTSANFRYETCSDEDVFCGKLVCTDVRYLPKVKPLHSLLQVPYGEDWCWSMDAYNITDVPDDGDVQSGTFCAPNKVCMEYICTGRGVLQYNCEPQEMCHGNGVCNNFKHCHCDAGFAPPDCSSPGNGGSVDSGPVGKPADRHLSLSFLAEESPDDKMEDEEVNLKVMVLVVPIFLVVLLCCLMLIAYLWSEVQEVVSPPSSSESSSSSSWSDSDSQ
What is the function of this protein?
May be involved in sperm-egg fusion.
What are the official names of this protein?
Disintegrin and metalloproteinase domain-containing protein 1a, ADAM 1a, Fertilin subunit alpha-a.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: UFC1_SALSA
Sequence: MADDATRKAVSEIPLLKTNSGPRDKELWVQRLREEYLALIKYVENNKTADNDWFRLESNKEGTRWFGKCWYIHDLLKYEFDMEFDIPVTYPSTAPEIAIPELDGKTAKMYRGGKICLTDHFKPLWARNVPKFGLAHLMALGLGPWLAVEIPDLISKGLITHREQQGS
What is the function of this protein?
E1-like enzyme which specifically catalyzes the second step in ufmylation.  Accepts the ubiquitin-like modifier UFM1 from the E1 enzyme UBA5 and forms an intermediate with UFM1 via a thioester linkage.  Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress.
What are the official names of this protein?
Ubiquitin-fold modifier-conjugating enzyme 1, Ufm1-conjugating enzyme 1.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family. UFC1 subfamily.
Protein: RTA1_LEPMJ
Sequence: MNAYAYTACLGIYGSTPNNEQLVLGSPDQLQRNKPRFRLIVLPHAPAASPFYPPWRSFAPDWEGQGARPMDHFKVGNLRFQLETHRIDEHSTFGKLFGHAPSPSQSCVSFQKKSDRAEPLLLARCSAASWSCIHPPTVLYFVAYQLEYPFAARFSATKISPIQDKMVATSDVPIVGSLYVYAPNKGAPIFFTIAFAISTILHSWQCHRYKAWKLIWLQPACAALFTLGYALREYGAYNYLYDGTEKAPLALFILSQICIYLGPPLLELANYHILGRVFHYVPYAAPFNPGRVTAFFGGLMAIVEGLSGSGVSLTANAKAKESTKKTGHNLLLVALALQVCVIFIFVYLSVLFHRRCIKAKVPAQSKAVKSTLMTLYLSMALIFIRCVFRLVEMATSSTSVDITSMERLMKLSPVLRNEAYFYAFEASLMLINSFLWNVQHPGPHLPGDTHIYLAQDGTEVEGEGDGSEDRPLLLNMANTLMFGLLYRDDKDHTHSQPQELYENPNGNGHKKFRLGNGGRAT
What is the function of this protein?
Lipid-translocating exporter-like protein; part of the gene cluster that mediates the biosynthesis of phomenoic acid, a long chain aliphatic carboxylic acid that does not appear to be essential for pathogenicity but may play a role in allowing to outcompete other fungi in the environmental niche via its antifungal properties.
What are the official names of this protein?
Lipid-translocating exporter-like protein RTA1, Phomenoic acid biosynthesis cluster protein RTA1.
What is the protein family that this protein belongs to?
Belongs to the lipid-translocating exporter (LTE) (TC 9.A.26.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RSMB_SHIB3
Sequence: MKKQRNLRSMAAQAVEQVVEQGQSLSNILPPLQQKVSDKDKALLQELCFGVLRTLSQLDWLINKLMARPMTGKQRTVHYLIMVGLYQLLYTRIPPHAALAETVEGAIAIKRPQLKGLINGVLRQFQRQQEELLAKFNASDARYLHPSWLLKRLQKAYPEQWQSIVEANNQRPPMWLRVNRTHHSRDSWLALLDEAGMKGFPHADYPDAVRLETPAPVHALPGFEDGWVTVQDASAQGCMTWLAPQNSEHILDLCAAPGGKTTHILEVAPEAQVVAVDIDEQRLSRVYDNLKRLGMKATVKQGDGRYPSQWCGEQQFDRILLDAPCSATGVIRHHPDIKWLRRDRDIPELAQLQSEILDAIWPHLKSGGTLVYATCSVLPEENSLQIKAFLQRTADAELCETGAPEQPGKQNLPGAEEGDGFFYAKLIKK
What is the function of this protein?
Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase B, 16S rRNA m5C967 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmB.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFSA_PECAS
Sequence: MDYTPRLQPARLIKRYKRFLADVVTPEGETLTLHCANTGAMTGCATPGDTVWYSTSDNPKRKYPQSWELTETQQNHWICVNTLRANTLLYEALLENRIEELAGYSDIKTEVKYGTENSRIDLLLQAPDRIDCYIEVKSVTLLQHECGYFPDAVTLRGQKHLRELQQMVSNGKRAVLFFAVLHSGIQQVSPARHIDSRYAELFIEAQQAGVEILCYGSTLCPDGIKLTNKLPLLG
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: PCKA_BACC0
Sequence: MSTVNVQIGLHELLNGSNAQIQLSVPQLVEKVLMRNEGKLTSTGAVSASTGKYTGRSPKDKFIVKEASVADKIAWGAVNQPISEEHFNKLYTKVLEYLKEKEELFVFKGFAGADRNYRLPIQVINEYAWHNLFVHQLFIRPTEEELTTHESEFTIVSAPNFKADPAVDGTNSEAFIMVSFEKRIVLIGGTEYAGEMKKSIFSIMNFLLPEQDILSMHCSANVGEEGDVALFFGLSGTGKTTLSADPNRKLIGDDEHGWSDNGVFNIEGGCYAKCVNLSHEKEPQIFDAITFGSVLENVIINDQTRIADYNDTTLTENTRAAYPMHAIDNIVLPSVAGHPNTIIFLTADASGVLPPISKLSKEQAMYHFLSGYTSKLAGTERGVTSPQATFSTCFGSPFLPLDASRYAEMLGEKIEKHDAKVFLVNTGWTGGEYGVGKRMNLGYTRAMIQAALNGELAKTETAKHDIFGLEVPLHVPGVPDEVLMPEQTWADKAAYKAKAIELANEFKANFKKFDSVSEDIINLGGPIA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOAA_PSEE4
Sequence: MEKNPQALVDGFNRKVDYLRMSVTDRCDFRCVYCMAEDMQFLPRQQILSLEELYQVAERFVALGTRKIRLTGGEPLVRQGIVELCGRIAALPGLRELCLTSNGSQLGRLAQPLFDAGVSRLNISLDSLDPERFRALTRTGDLKQVIAGIDAARAAGFRRTKLNAVVLKGRNDDEIVDLVRFAIDRELDISFIEEMPLGVISEHERGESFCSSDDVRNRLAEHFTLVESAESSQGPARYWRLAEAPSTRVGFISPHSHNFCATCNRVRLTVEGRLLLCLGNEHSVDLKQVLRQHPGDSARLEKAIRDAMQLKPYRHHFEVGGEVQILRFMNMTGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: DNLJ_CHLT3
Sequence: MNKSEAEAKIRALRREINEHNYNYYNLAKPKISDYDFDALLRTLAELEAKYPDLVTPDSPSQRVGGEVTKNFPIVRHKTRMLSLSNTYNLGELGDFLARVAKSLESEGVQAYDFTAELKYDGVAVSLIYRDGLLVQGATRGDGSQGDEITANLKTVRTIPLRLRAPASGSAFDTEKWNGSGDIEVRGEVFMTKADFEKINAERDESEQFANPRNATAGTLKQQDSREVAKRRLTMVAYYLDGRPFADLSHGERLEKLAELGFYTGEAHRTCRSLQDIQAFLDEWENKRDALAYEIDGAVIKLNNVRYQELLGATSKSPRWAIAYKYAARRAETVLENVVFQVGRTGAITPVAELQPVKLSGSVISRSTLHNLDEIRRLDLHIGDRVIIEKSGDVIPKVVGVVAEKRPPEARTIEPLSTCPSCGTPLEHPENEVIYYCPNEFGCPAQRKARLVHFASRHAMDIEGLGEAVVEQLLGAGLIGDPGDLYFIEKTALLALERFAEKSAQNLLNGIEASKSRSFERLIFALGIRYVGRRTASILADRFTSLDTIKSASQAELCETEEIGETIAKSVALFFTKPQVQELLGKLERAGLRLASDKKSPDAPQTFAGMTVVFTGSLENFTRDDAAAKVGERGGKVTSTVSKKTSLVVAGKEAGGKLAKAEKLGVKIVTEAEFQTMLAAESGD
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: END4_THEAC
Sequence: MIDEAIRSISKKYTIGGHISVAGGLHNGPARAAVFGFPTFQFFSKNQMRWSSPPLKDDEAAAFKSEVRKYGIESTMIHASYLINLASADPDLYKRSMEAFHDEIDRSDKLGSTFLTVHPGSNPDRADGIRRVRDALSTIGDHAVIILIENTAGQGNVIGTRLDEVAKIIDTSDKKLGVCIDTCHAWASGYDLRDSLEKFIESLDYTIGLDRIFAFHLNDAKREMGSRIDRHELIGKGTIDGGLINLIRDDRLRAKPKIMETPFGEARFEDNLRYMSSKIGE
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: RL19_ECOUT
Sequence: MSNIIKQLEQEQMKQDVPSFRPGDTVEVKVWVVEGSKKRLQAFEGVVIAIRNRGLHSAFTVRKISNGEGVERVFQTHSPVVDSISVKRRGAVRKAKLYYLRERTGKAARIKERLN
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: Y2896_CERS5
Sequence: MTESPQFDRRMLEALVCPVSQSGLSYDAERQELVSRQARLAFPIRDGIPIMLVSEAREL
What are the official names of this protein?
UPF0434 protein Rsph17025_2896.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: ALG14_KLULA
Sequence: MLLTTAWCLLIWSVTLLLVRICLVIPIFHSSREAGPLTKDKDNVGGRMKNLVLFIFLGSGGHTGEMLRLIEHYQGMLLESAVTIHVGYSDDDSIIKFKNKIHQISVSNTLRAKVIYHRFDKARDVGSSLAGSIKSIIKTAIRSMVLTYRIKSSMRGHPNLTLLNGPGTCCIITFWLKLYHIFLWQPSKIVYVESLARTNRLSLTGMILYPLADEFVVQWADLLPIYPKAKYYGVLV
What is the function of this protein?
Involved in protein N-glycosylation.  Essential for the second step of the dolichol-linked oligosaccharide pathway.  Anchors the catalytic subunit ALG13 to the ER (By similarity).
What are the official names of this protein?
UDP-N-acetylglucosamine transferase subunit ALG14, Asparagine-linked glycosylation protein 14.
What is the protein family that this protein belongs to?
Belongs to the ALG14 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus membrane; Single- pass membrane protein.
Protein: FDHD_ANADE
Sequence: METSLKRAAAPAGAVAERTVLRNGGAVRDALAVEEPLEIRVDGERLATTMRTPGADGDLALGFLFAEGIIAGVEDVGTVIHCGRPGEEGYGNVMDVRSAAGMRIDPERVLEGRRFIPVSAACGVCGRLSIDHLMERLRPLPAGEPVPTALVAAGMETLARSQPVFERTGGLHAAVLVGRDGAPVASAEDVGRHNAVDKVVGAALRAGRVGPRAAAASAPALLAVSGRAGFEIVQKAAAAGVPVVASVSAPSSLAVDLARAAGVTLCGFVRGERMNVYANGERLGLTGP
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity.  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
What are the official names of this protein?
Sulfur carrier protein FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_RICRO
Sequence: MTKIVRSKYKASRRLGVSLWGDSKDAFNTRNYRPGQHGQNTMIKTSDYGLHLKAKQRLKCHYGRVTEKQFRNIFALAQKMKGNTGENFIGLLESRLDTVVYRMNIAPTIFAARQLVSHGHIKLNGKKADIASIRLKAGDVIEVKESVKQIPLIQESVSKQGQTTPGYLSFDVPSLTGKYLRVPALSDVPYPFEAEVHLVIELYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: PGAP3_BOVIN
Sequence: MAGRTARLVLLAGAAALASGSQGDREPVYRDCVLRCEERNCSGGALKHFRSRQPIYMSLAGWTCRDDCKYECMWVTVGLYLQEGQKVPQFHGKWPFSRFLCFQEPASAVASFLNGLASLVMLCRYRTSVPASSPMYPTCVAFAWVSLNAWFWSTVFHTRDTDLTEKMDYFCASTVILHSIYLCCVRTVGLQHPAMASAFRALLLLLLTAHVSYLSLIHFDYGYNMAANVAIGLLNAAWWLAWCLWNQRLPHVHKCVAVVLLLQGLSLLELLDFPPLFWVLDAHAIWHISTIPVHVLFFSFLEDDSLYLLKESEAKVKLD
What is the function of this protein?
Involved in the lipid remodeling steps of GPI-anchor maturation.  Lipid remodeling steps consist in the generation of 2 saturated fatty chains at the sn-2 position of GPI-anchors proteins.  Required for phospholipase A2 activity that removes an acyl-chain at the sn-2 position of GPI-anchors during the remodeling of GPI (By similarity).
What are the official names of this protein?
Post-GPI attachment to proteins factor 3, PER1-like domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the PGAP3 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Mainly localizes to Golgi apparatus.
Protein: NDK_THEAB
Sequence: MERTFVYLKPNAVRRGLVGEIIKRFEQRGIKIVALKLLWMSKQQAEKLYEMHKGKSFYNDLIDFVTGGPIVAMIVEAPRVIEMVRHIIGDTDPLKAGTGTIRGEFALTITKNLIHASDSKENFEREYKIFFSDDEIIDYYLDVQDDI
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_EHRCJ
Sequence: MIFDEDSNSVTQDSGYMTVGNAYSNAVGYISMSDHWSKLTKPSSIKVESNGASPNKADLIVEPLESGFALTLGNALRRVMMSSLRGFAVYGVEIENVLHEFTSISGVREDVTDILLNISMMRVKLSGLSNKVLSLRVKGPCEVRSGMIPDTDDCIILNKDLLICTLDQDVDFNIKMYVNSGKGYVPAVKRKSVSKLSDVPVNFIATNALYSPIKKASFKVESSRIGQFTDYDRLVLSVETDGSILPDEAVALAARILQDQFQPFINFDETDEPHKKIDTKDALPYDSNLLRKVDELELSVRSYNCLKNDNITYIGDLVQKTESDMLRTPNFGRKSLNEINELLASMNLHLGMKIANWPPESIESLSKQYSEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: MURQ_HAES1
Sequence: MNKQNLINQFAQLITEQPNPRSVNLDQMSALEIVQLMNKEDQQVPLVIAKALPEIAVVVEKIVAAFRQGGRLVYLGAGTSGRLGVLDASECPPTFGVNHEMVKGIIAGGEQAIRYPVEGAEDNQQAAIVDLQAIQLCSKDILVGIAASGRTPYVISGLKYAKEIGSFTVAIASNPQSAMAKIADMSIETIVGPEILTGSSRLKSGTAQKLVLNMLTTASMVLLGKCYQNFMVDVQASNEKLVDRATRIIMQATGCERAKAEQTLTQADNNAKLAILMILMDLDKQSAVDLLAKNQDKLRQTLD
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.  Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: KORB_METTM
Sequence: MNVKENPYLKYLRRDRLPHIFCAGCGNGIVLNTFFKGMEMAGVDFDSIAMVSGIGCSSRIPGYVKCDSLHTTHGRPIAFATGLKLANPSLNVVVFTGDGDAAAIGGNHLIHGARKNIDLTVICINNSIYGMTGGQISPTSPEGSFGTTAPYGALEDPFDLSELVRAAGASYVARWTAAHPLQLANSIKKGLKNRGFSFIEAVSQCPTYFGRKNRMRSPVEMMKFMKENSINRRKALKMDPEEVEGKLIIGEFADAPRPELCDRIYGMIEEKSGKIDIIKSAYRDD
What are the official names of this protein?
2-oxoglutarate synthase subunit KorB, 2-ketoglutarate oxidoreductase beta chain, KOR, 2-oxoglutarate-ferredoxin oxidoreductase subunit beta.
Protein: STE20_DEBHA
Sequence: MYKAKDTEYKLGSPIHEKIPSFEIGSDRRLDIDDNEGEEVSARDEHDDDEDYEYKRIIEEEFENDREFKDEHGFEIGVVDNDENNDQDCEADTSKSIGSLPRMPGTYDFSGLKSDDNQYNELTETLNQDDGNQSNDIAVGKLGDEASHTYKSTLDPGKPLQNPPPSNLNIDSILKSQLENNKSEGSIGQRIDSISRKTTNSSGGPNIMKDNTLDRIPTHDYENIDDNNVFNRAGDPKIRGGLNASNDASINDNIADISQSTIQTSTDAGESINKGNGDITKGLSNVDVNDTSVNKSKQRNISSGSVIRNPPSASQANQSNQSYHQTRAITPVMNQMNKFQGSNSEASSPREHLGMGINNSAPSTGANSNTSSPMNGSYPNSIAKSRRSGNRVKGVFSNMFSKNKTSTSVTSSPETHAINMKISTPFNAKHVAHVGVDDNGSYTGLPIEWERLLSASGISKKEQQQHPQAVMDIVAFYQDTNDDNPDENAFKKFHYDNDSSHSSIYNATPPSTPGIPSTYNATPLQSEKQLQRQQSQKSQSSHPVQVQSTPKTPNNNYENQFIPSRPAPKPPSSSIPSTKTIKPPPVPPSPSTNTNISPASKKNSFMGRSFSSKSIKALRNSNRKISEPPKAPQSKISDSNTEMGIPKSKSHSNSLSTQSEVEPTKGSTTAPVSSTAKFNSTTINNINGHNIIEEEKNNNTLLSNPKQREQKPDSTIEKRDTPPSPSQSRVSEEESTKKETSEKYNNKENDIPKKSSQQPVRDAKQAALLAQKKREDKKRKNQQIISKLQQICSEGDPNELYKDLMKIGQGASGGVYIAHDVNHRSQTVAIKQMNLEQQPKKELIINEILVMKGSKHENIVNFIDSYLLRGDLWVVMEYMEGGSLTEIVTHSVMTEGQIGAVCRETLKGLRFLHSKGVIHRDIKSDNILLNIDGNIKMTDFGFCAQINEINLKRTTMVGTPYWMAPEVVSRKEYGPKVDVWSLGIMIIEMIEGEPPYLNETPLRALYLIATNGTPKLKEPEALSYDIRKFLSWCLQVDFNKRGNADQLLNDKFILEADDVESLSPLVKIAAMKKATELDE
What is the function of this protein?
MAP4K component of the MAPK pathway required for the mating pheromone response and the regulation of cell polarity and cell cycle.  Phosphorylates histone H2B to form H2BS10ph (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase STE20.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: UVRD_RICBR
Sequence: MPNHDFLHSLNEQQQKAVLHTEGPLLLLAGAGTGKTKVLTSRIANIIHQNLASPQNILAVTFTNKAAKEMQERVHNLVSSYGLNIGTFHSMAARILRDQIEHLNLGLNSRFTIISQDDQLRLIKDIVKLKNIDTKKYAPKLIHIVISRWKDQGLLPNKLSSSDTNLPLQRVAKLVYEEYQQNLLISNVVDFGDLLLYNNELFIKNPDILKHYQERYRYILIDEYQDTNVVQYLWARMLASLSKNICCVGDDDQSIYGWRGAEVGNILRFEKDFLNATIIKLEQNYRSTLPILAAASNVINNNKNRHGKTLWTDKESGEKIKIISCWNDKEEARYIAAEIARLVREGRYSAGNIAILVRAGFQTRSFEEAFINSAMPYKIIGGLRFYERMEIRDVLAYIRIALNQNDNLALERIINVPKRAIGAVTLNKIKLYAIEKNISNFAAIKEMLEDGEIKTKSYETLKDLVTKISNWHERFSFDAPINVTKAILDDSGYLEMLQEEKTEEALGRIENINEMLRAIAEFNDIHDFIEHSSLVMENESLETSYGGSVTIMTLHGAKGLEFDVVFLPGWEEGVFPSQRSLDEEGEKGLEEERRIAYVGITRAKKELYITHAESRKIFYEIVRSYPSRFLAEIPEEIIIRTSSIKKYDSFYKF
What is the function of this protein?
Has both ATPase and helicase activities.  Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present.  Involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair (By similarity).
What are the official names of this protein?
Probable DNA helicase II homolog, DNA 3'-5' helicase II.
What is the protein family that this protein belongs to?
Belongs to the helicase family. UvrD subfamily.
Protein: MATK_NICPA
Sequence: MEEIQRYLQPDRSQQHNFLYPLIFQEYIYALAHDHGLNRNRSVLLENPGYNNKFSLLIVKRLITRMYQQNNFLISTNDSNKNEFLGCNKSLYSQMISEGFAFIVEIPFSLRLISSLSSFEGKKIFKSHNLRSIHSTFPFLEDNFSHLNYVLDILIPYPVHLEILVQTLRYWVKDASSLHLLRFFLHEFWNLNSLITSKKPGYSFSKKNQRFFFFLYNSYVYECESTFVFLRNQSSRLRSTSFGALLERINFYGKMERLVEVFTKDLQVTLWLFKDPFMHYVRYQEKSILASKGTFLLMNKWKFYLVNFWQCHFSLCFHTGRIHINQLSNHSRDFMGYLSSVRLNPSMLRSQMLENSFLINNAIKKFDTLVPIIPLIGSLAKANFCTVLGHPISKPVWSDLSDSDIIDRFGRICRNLFHYYSGSSKKKTLYRIKYILRLSCARTLARKHKSTVRTFLKRSGSELLEEFLTSEEQVLSLTFPRASSSLWGVYRSRIWYLDIFCINDLANYQ
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: KAIB_ACAM1
Sequence: MSSIRKTYVLKLYVAGNTPNSVRALRTLNHILETEFQGVYALKVIDVLKNPQLAEEDKILATPTLAKVLPPPVRKIIGDLSDRERVLIGLDLLYEELSDGIMEY
What is the function of this protein?
A metamorphic protein which reversibly switches between an inactive tetrameric fold and a rare, thioredoxin-like monomeric fold (KaiB(fs)).  KaiB(fs) binds phospho-KaiC, KaiA and CikA.  KaiA and CikA compete for binding to KaiB(fs), and KaiB(fs) and SasA compete for binding to KaiC, thus the clock oscillator and output signal pathway are tightly coupled.
What are the official names of this protein?
Circadian clock oscillator protein KaiB.
What is the protein family that this protein belongs to?
Belongs to the KaiB family.
Protein: F228A_BOVIN
Sequence: MSNCGKHFGPEQLEKWPELESVTLMEALAREDIDEAVYAILFRENCIAKRLDTYFQHLDAFKERKKELLHKKWTENVAKPLQQRIMEKVISYKALEKTKQENFEYFLKHTNKTEIIFGDFYDPEVYNPFYMTKKDPNYGKVAVPPFCDPLFIRQQEIDEEQRAVFQYTTGKRCTLKEFKELEKARQYARLPQFTFSLHSMVSKDRPKAFARPVGSKTHSKCSPEKLVCAEEKFPPYKVKMTSDVNQTVFERRFYSSKISQESKRHEKKGLALGTGQHRPRSWAAGEGQQRRRSQPVDRRVMTAEVLGQHLAALQLGDR
What are the official names of this protein?
Protein FAM228A.
What is the protein family that this protein belongs to?
Belongs to the FAM228 family.
Protein: PPI1_BRUAB
Sequence: MSFIRSALAAAAFVALSIGAVQTASAADPENTVILKLKDGDVALEIRPDLAPKHVAQIKKLVREGAYNGVAFHRVIPGFMAQTGDVKFGNMDKGFDAARVGTGGSNYPDLPAEFSKEPFVRGTVGMARSQNPNSANSQFFIMFDDGPFLNGQYTVVGKVVSGMDAVDKIKKGSEAENGAVKNPDKIIKATIEADTK
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Probable peptidyl-prolyl cis-trans isomerase, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family.
What are the subcellular locations of this protein?
Periplasm.