PharMolix/UniProtQA huggingface dataset:
Protein: YIDC_CHLCH
Sequence: MDKNSVTGLALIAVIMLVWLQFMTPAQKVQPPQQVATTEQQVASASLPLPAALSPSTDTFGLFATASQGSEQVTVVENDLFRATLSSKGATLKSLVLKKHLDGHLQPFDLLGKQKNGHLSLLFLTKDGKRIDTRDLYFRNVTLETKRTISGQERYTVRYRLDVAPQKAIEIAYLFSGESYAIDYDVKLIGFGNDIAGNEYQVQWDGGLAYTEKNREEESQNALAGAYLGGSLVKLDAAKEKEVFREEQSGEATWVGVRNKYFTAALIPQSKSNGIYLEGKREAGNHFENYLAALKMSLPASATEVHNTFTMYVGPLDYNTVKAQGVGLEKIMDFGWDWLTRPFAEWMILPVFNWLNGFISNYGIIIIIFAFLVKLVTYPLSMASTKSMKKMAALQPVLQELQVKYKDNPAKMQSELSRIYREAGVNPVGGCLPTLLQMPLLFAMFYVFRSSIQLRQHGFLWAKDLSVPDSIFDFGFAIPLYGDHIAFFPILMAGTVYLQQKITPTAQPNEQMKIMLVLFPVMMLFFFNNMPAGLGLYYLMFNIFSVAQQFYINKTTTADDMPKVNLAPVASNASKKQKKGGAKK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ARO1_CANAL
Sequence: MSIEKVPILGKETIHVGYGIADHIVREVIANLASSTYVIVTDTNMARTPQYSKLTDDFKTNLSEKRPESRLLTYCVSPGENNKNRATKAAVEDFLLQQGCTRDTVILAVGGGVIGDMIGFVAATFMRGVRVVQVPTTLLAMVDSSVGGKTAIDTPLGKNFIGAFHQPEYVFCDVSFLETLPARQFINGMAEVVKTAAIWNEEEFTRLENFSKKFLSVVTSKKPDLQSIKAELVKTVLESVRVKAGVVSSDEKEAGLRNLLNFGHTIGHAIEAVLTPEALHGECVSIGMIKEAELSRYLGILPPVAVARLSKCLVAYGLPVSIDDKEFLKKVGPKRHYVEIDILLKKMAIDKKNDGSKIRCVLLEKIGKCYQLKAHQVSKQDLSFVLTDEVLVHPFTNPPKENIIVPPGSKSISNRALILAALGNGTVRVKNLLHSDDTKHMLDAVASLKGAEISTEDNGETIVVKGNGGNLVTSGEELYLGNAGTASRFLTTVASLVGKSQASDDVILTGNARMQERPIGPLVDALGSNGSEIEYLNKQGSLPLKISAGNGLKGGRIELAATISSQYVSSILMCAPYAKEPVTLALVGGKPISQLYIDMTCAMMKSFGIEVTKSTTEEYTYHIPKGTYKNPSEYVIESDASSATYPLAFAAMTGTSCTIPNIGSSSLQGDAKFAVDVLKPMGCKVEQTTTSTTVTGPPRGHLKPLPHVDMEPMTDAFLTASVVAAVAKGGSSTSITGIANQRVKECNRIEAMVTELAKFGVPANELPDGIEIHGIDIEDLKTPEISKRGVSSYDDHRVAMSFSLLAGLCKEPVLILERSTTGKTWPGWWDILHSKFKIELDGYEPPFNTDKHVDKSSDKSIIVIGMRGTGKSTLSEWLASFLGFKMLDMDKYLEEKLGTGIKSLIKAKGWEYFRQEEAIVAKECFTKFSKGYVLSTGGGIVEGEDARQQLKSYADNGGIVLHLHRDLDETVTFLAADTTRPAYSSEVQEVWLRREKWYHECSNYHFYSSHCSTEDEFNHLRRSFVNYIKLITGAERPVVPAGRSAAVVLTSPDLNEVVGDLESITIGADAVELRVDLFKDTSAEFVAAQIAVIRKHADLPIIYTVRTVSQGGKFPDENVDELKSLLLLGIRLGVAYVDLQLTAPNELIEEISSKKGFTRVIGTYQDINGELKWNNVEWKNKYNQGVSMNADIVRLVGKANSIQDNLDLENFKKQNTLKPLIAFNLGSQGKLSQVLNGTFTPISHKLLPNDEEFLTIGELNQTYFDIGGFTAKKFWVIGSPIEHSRSPNLHNAGYKALNLPYQFGRFEATDVDVVYDNLINKPDFGGLAITMPLKLDIMKFATKLSDAAETIGAVNTLIPIEGGYFGDNTDWVGISNSFIRAGVPPKSSSNGLVVGAGGTSRAAIYALHQMGCAKIYLVNRTAAKLEELVKSFPKDYNLEIVETEQQADKASKVSLAVSCIPADKPLDGEVLKKIERILSNGSEQSAGFKPTLLEASYKPRVTPIMKLTEEQYKWKVIPGVEMLVNQGDRQFKLHTGFTAPYEIIHRAVVEE
What is the function of this protein?
The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.
What are the official names of this protein?
Pentafunctional AROM polypeptide.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the shikimate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GMD1_CAEBR
Sequence: MEGLEACIGQSHEVMTTPAAELAAFRARKVALITGISGQDGSYLAELLLSKGYKVHGIIRRSSSFNTARIEHLYSNPMTHNGDSSFSLHYGDMTDSSCLIKLISTIEPTEVYHLAAQSHVKVSFDLPEYTAEVDAVGTLRLLDAIHACRLTEKVRFYQASTSELYGKVQEIPQSEKTPFYPRSPYAVAKMYGYWIVVNYREAYKMFACNGILFNHESPRRGETFVTRKITRSVAKISLGQQESIELGNLSALRDWGHAREYVEAMWRILQHDAPDDFVIATGKQFSVREFCNLAFAEIGEVLEWEGEGVEEVGKNKDGIVRVKVSPKYYRPTEVETLLGNPEKAKKTLGWEAKVTVPELVKEMVASDIALMKANPMA
What is the function of this protein?
Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.  Involved in susceptibility to pore-forming crystal toxins in conjunction with bre-2, bre-3 and bre-4.  Has a role in determining brood size (By similarity).
What are the official names of this protein?
GDP-mannose 4,6 dehydratase 1, Bacillus thuringiensis toxin-resistant protein 1, Bt toxin-resistant protein 1, GDP-D-mannose dehydratase, GMD.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
Protein: KATG_XYLFM
Sequence: MRDMRASSPETTSAVKCPFNKTAVEGTHNKDWWPNQLRVDLLHQHSNKSNPLGETFDYAKVFQKLDYAALKRDLHALMTDSQDWWPADFGHYGGLFIRMAWHSAGTYRIGDGRGGAGRGQQRFAPLNSWPDNVSLDKARRLLWPIKKKYGQQISWADLIVLAGNVALESMGFKTFGFAGGRVDTWEPDQDVYWGREMTWLGGDVRYGAVSEGVHHPDEHSGAKEKASKNSDSRVLENPLAAVQMGLIYVNPEGPDGRPDPLASARDIRETFARMAMNDEETVALIAGGHTFGKTHGAAPADNVGPEPEAGELEQQGLGWHNRFGSGKAGDTITSGLEVTWTKTPTQWSNDFFEHLFGYEWELTKSPAGAYQWVAKDAAATIPHAHDPSKKLLPMMLTSDLALRFDPVYEKISRHFHAHPDQFADAFARAWFKLTHRDMGPRVRYLGPEVPAEELIWQDPVPKVSHVLVDAQDLLALKHKISASGLGISQLVSTAWASASTFRGSDKRGGANGGRLCLAPQNQWEVNQPQQLSVVLETLRRVQTEFNAQAGDKRISLADLIVLAGGVGVEQAAKRVGIVVEVPFVPGRTDALQEQTDVSSFAPLEPFADGFRNYVKGDEVVPSEHLLIDRAQLLTLTAPEMTVLIGGLRVLGANVGGVKHGVFTDRLGTLSNDFFINLLDMGTEWAPVSKERHVFEGRDRRTGVLKWTGTRVDLVFGSNALLRALAEVYAAVDAQEKFVRDFVAAWSKVMHLDRFDLV
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: RL18_PYRAB
Sequence: MAHGPRYRVPFRRRREGKTNYRKRLKLLKSGKPRLVVRKSLNHHIAQIIVYDPKGDRTLVSAHTRELIRDFGWKGHCGNTPSAYLLGLLIGYKAKKAGIEEAILDIGLHPPVRGSSVFAVLKGAVDAGLNVPHSPEIFPEDYRIRGEHIAEYARMLKEQDEEKFRRQFGGYLEKGLDPEKLPEHFDEVKARIIEKFESEGARE
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RL23_BARHE
Sequence: MKNLRHYDVIVSPIITEKSTMISEYNQVAFNVAPKATKPEIKAAVEALFSVKVKAVNTIVRKGKVKRFKGIVGRQNDVKKAIVTLASGQSIDVSTGL
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: HOA2_SALAI
Sequence: MSVKLQICDSTLRDGNHAVAHQLGRADISAYARAAEEAGVDVLEVGHGNGLGASSIQVGIAAVSDAEMLRAAKAELRNSRLGVLSIPGFASVERDLKPALDCGVDEVRVGAHCTEADVTRQQITMLRSMGVRVKGLLLMSHMASAGKLVEQAGLMQEYGAEAVVLMDSAGAYTPEMVREKVGELVEKLDIAIGFHAHNNLGLSVINSITAVRAGASIVDVTARGFGAGAGNAPIELVAANLHVEQIEARIKLFDALDAADTAEERFVKHVPTNDGVTIASGIAGVFSGFAAPVRRASRRFGVDPREILLELGRRRVVAGQEDTIIEVAMALAAEAASADLTHAFVDHI
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase 2, HOA 2, 4-hydroxy-2-keto-pentanoic acid aldolase 2, 4-hydroxy-2-oxopentanoate aldolase 2.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: VPC13_MYCTO
Sequence: MILVDSNIPMYLVGASHPHKLDAQRLLESALSGGERLVTDAEVLQEICHRYVAIKRREAIQPAFDAIIGVVDEVLPIERTDVEHARDALLRYQTLSARDALHIAVMAHHDITRLMSFDRGFDSYPGIKRLA
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  An RNase.  The cognate antitoxin is VapB13 (By similarity).
What are the official names of this protein?
Ribonuclease VapC13, RNase VapC13, Toxin VapC13.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: ARAB_ECOUT
Sequence: MAIAIGLDFGSDSVRALAVDCATGEEIATSVEWYPRWQKGQFCDAPNNQFRHHPRDYIESMEAALKTVLAELSAEQRAAVVGIGVDTTGSTPAPIDADGNVLALRPEFAENPNAMFVLWKDHTAVEEAEEITRLCHAPGNVDYSRYIGGIYSSEWFWAKILHVTRQDSAVAQSAASWIELCDWVPALLSGTTRPQDIRRGRCSAGHKSLWHESWGGLPPASFFDELDPILNRHLPSPLFTDTWTADIPVGTLCPEWAQRLGLPESVVISGGAFDCHMGAVGAGAQPNALVKVIGTSTCDILIADKQSVGERAVKGICGQVDGSVVPGFIGLEAGQSAFGDIYAWFGRVLSWPLEQLAAQHPELKEQINASQKQLLPALTEAWAKNPSLDHLPVVLDWFNGRRTPNANQRLKGVITDLNLATDAPLLFGGLIAATAFGARAIMECFTDQGIAVNNVMALGGIARKNQVIMQACCDVLNRPLQIVASDQCCALGAAIFAAVAAKVHADIPSAQQKMASAVEKTLQPRSEQAQRFEQLYRRYQQWAMSAEQHYPPTSAPAQAAQAVPTL
What are the official names of this protein?
Ribulokinase.
What is the protein family that this protein belongs to?
Belongs to the ribulokinase family.
Protein: TRMD_HAEDU
Sequence: MWIGIISLFPEMFKAITDFGVTGRAIKQNLLQIECWNPRDFTFDKHHTVDDRPYGGGPGMLMMVQPLRDAIQVAKQVARSEDGVEAKVIYLSPQGRKLDQQGVRELSANRKLILICGRYEGVDERLIQSEVDEEWSIGDYVLTGGELPAMTLIDAIARFVPGVLGKQASALEDSFAEGLLDCPHYTRPEVLDNMPVPQVLMSGNHEQIRKWRLAQSLERTWLRRPELLDSLALTDEQRVLLAKIKQQYKIS
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_METM5
Sequence: MEIKLFGKWDSETVTVKDPSLKSYISVAPVLVPHTAGRNTKKSFDKAKMNIVERLANKLMANQNNTGKKHETLAIVEEALAIIENRTKENPVQVLVDALENSGPREETTRISYGGIAFLQSVDVSPSRRLDTAFRNIALGASDSAHKNKKTVAQCLADEIIFASKADMQKSFAVRKKEEKERVAQSAR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: ILVD_LEPIC
Sequence: MGDNLKKRSSMTTDGDNRAPNRAMLRAVGFTDEDFHKPMIGIASTWSEITPCNIHINKLAEKVKEGVREAGGVPQIYGTITVSDGIMMGHEGMHFSLPSREVIADSIEIVSNAMRHDGVIAIGGCDKNMPGCLMALCRIDAPSIFVYGGTILPGNCDGQDVDIVSIFEAVGKFNAGKISREEFIRIEQNAIPGAGSCGGMYTANTMSSAIEALGMSLPGSASMPAVSSRKANDCYEAGKALINLIQKGITPKQILTKKAFENAITVVLVLGGSTNAVLHLIAIAKEIGVGLTLDDFDRISKKTPHLADLKPGGKYAMTDLDKVGGVHGVMKYLLKEGMLHGDCLTVTGKTIAENLKDMPDLVPNQTIVRKKSEALHPSGPLVILKGNLAPDGAVAKISGLKKISITGPAKVFESEDDCFNAIMTDKIKPGDVIIIRYEGPKGGPGMREMLAVTSALVGKGLGEDVGLMTDGRFSGGTHGLVVGHISPEAFDGGPIAIIQNGDKVTIDSSKNLLQVEISQEEIDKRLKSWKPIEPRYKTGVLAKYVKLVQSATNGAITNLL
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: DER_ECOSM
Sequence: MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAEIEGREFICIDTGGIDGTEDGVETRMAEQSLLAIEEADVVLFMVDARAGLMPADEAIAKHLRSREKPTFLVANKTDGLDPDQAVVDFYSLGLGEIYPIAASHGRGVLSLLEHVLLPWMEDLAPQEEVDEDAEYWAQFEAEENGEEEEEDDFDPQSLPIKLAIVGRPNVGKSTLTNRILGEERVVVYDMPGTTRDSIYIPMERDGREYVLIDTAGVRKRGKITDAVEKFSVIKTLQAIEDANVVMLVIDAREGISDQDLSLLGFILNSGRSLVIVVNKWDGLSQEVKEQVKETLDFRLGFIDFARVHFISALHGSGVGNLFESVREAYDSSTRRVGTSMLTRIMTMAVEDHQPPLVRGRRVKLKYAHAGGYNPPIVVIHGNQVKDLPDSYKRYLMNYFRKSLDVMGSPIRIQFKEGENPYANKRNTLTPTQMRKRKRLMKHIKKSK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: RL1_SACEN
Sequence: MAKRSKAYQQAAELVDRARLYAPLEAAELAKKTAKVKMDPTVEVAMRLGVDPRKADQMVRGTVNLPHGTGKTARVIVFAVGDKAAEAEAAGADAVGSEDLIERIQGGWLDFDAAIATPDQMAKVGKIARVLGPRGLMPNPKTGTVTPNVTKAVADIKGGKINFRVDKQANLHIVIGKASFDTDKLVENYAAALDEILRAKPSTSKGRYLKKVTFTTTMGPGIPVDPNRTRNLLEPAQV
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: PTC71_DROSE
Sequence: MITRLKNWPCLLKRFSIQQIHQFTHLSGRFERAPQSSKSPRDPYLVTVVQGRSKKPRFPGERSNQRFGEDSWFVNSTPLAEVMGVADGVGGWRDLGVDAGRFAKELMSCCSGQTQLSDFDGRSPRNLLIAGFQELSHREQPVVGSSTACLATMHRKDCTLYTANLGDSGFLVVRNGRVLHRSVEQTHDFNTPYQLTVPPEDRKESYYCDKPEMAVSSRHSLLPGDLVLLATDGLFDNMPESMLLSILNGLKERGERDLLEGASRVVEKARELSLNASFQSPFAIKARQHNVSYSGGGKPDDITLILSSVEVPSV
What are the official names of this protein?
Protein phosphatase PTC7 homolog fig, Fos intronic gene protein.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: PYRB_SYNC1
Sequence: MAFNHKHILGIEQMSAEDITLILDTAESFKDVSLRSIKKVPTLRGKTVINVFFEASTRTRTSFEIAGKRLSADTVNISASTSAVVKGETLEDTAKNLEAMKPDIIVMRHSCSGAPHYLAERCDFSVINAGDGAHEHPSQALLDLLTIRQKKGHIEGLTVAIIGDITHSRVARSNVYALNKLGAEVRLCGPGTMLPPGIERLGAQVFDRIDDAVSGADVVMMLRIQQERQGKTMLPSLREYSMFYGLTPDRMKLAKPDAIVMHPGPMNRGVEISSAVADGPQNVILDQVENGVAVRMALLYLVSGGEKLEDSAQ
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: VE4_BPV4
Sequence: KQSSFSLCYQFASCWEIRRTTRVPKPGTQPEDDDDRPPIFQRRPGPAAEGAVVFAIAITVTITIAYEGAALQWTRHAATESRETPGRKTKGHPRTGTMPWNTDSANS
What are the official names of this protein?
Probable protein E4.
Protein: METK_WHEAT
Sequence: MAAVDTFLFTSESVNEGHPDKLCDQISDAVLDACLAEDPDSKVACETCTKTNMVMVFGEITTKANVDYEKIVRDTCRGIGFVSNDVGLDADHCKVLVNIEQQSPDIAQGVHGHFTKRPEEIGAGDQGHMFGYATDETPEFMPLSHVLATKLGARLTEVRKNATCPWLRPDGKTQVTVEYHNDNGAMVPIRVHTVLISTQHDETVTNDEIAADLKEHVIKPVIPEQYLDENTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYVARQAAKSIVASGIARRCIVQVSYAIGVPEPLSVFVDTYGTGKIPDKEILEIVKENFDFRPGMIIINLDLKRGGKGRYLKTAAYGHFGREGADFTWEVVKPLKWEKPSA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.  The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, Methionine adenosyltransferase, MAT.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDRP_PZSVT
Sequence: MAAFTFENFLSGAYTGLPIDKFRALGLNTEDYDEQRWEMLVKCVDSGLMQFSCSRDEALVLLWNEEELPKDDDDEVPYEVPCWTPDTDATVIDDVSEWLAEKTSVRDTVVVCSDYDAVSETPVEVLSVELEEDSEEDTIADVCLDARRKSFRDYFTIVEEEFVEEDPLISLNDGNVCPVRTHEVTSLEKPVMLDVGRRCDRVNLESLQGAINMNLPSHAYFDDTWHQYFVEGSKLDVDFDNIRLRQSEVFCDRDLDRYYQPELFAGASSRRIGTQKEALVAIRKRNADVPELADSVDVERLSESVAKKFLSSYVCDLKPVVGVMEKMRAYHQKWGDKIDPMFLLKEHNLQRYEHMIKTDVKPTVAHSMHVERAIPATITFHGKSICAGFSPSFTALFDEFQKSLDERVVIPSGPISTIEMDFDIRNKYYLEVDLSKFDKSQGLLHLEFQRKILCKIGLPAHLANWWCDFHYKSFISDPRAKVSFNCSFQRRTGDAFTFFGNTLVTMAMFSFCYDTRQFEKMLFAGDDSLAISSSPIVGCSDYFVSLFNMEAKIMDPGVPYICSKFLVSDELGRCFSAPDPIREFQRLGKKKISADNDDALFEQYVGFKDRMSHMRNFSEYEIQQLKIFFNLKYKQSGEVIEDYMGACMFYSDNFKNFKTLFTKTCAPLVAALNKRVKDKPFRLPPSL
What is the function of this protein?
RNA-dependent RNA polymerase which replicates the viral genome composed of 3 RNA segments, RNA1, RNA2 and RNA3.
What are the official names of this protein?
RNA-directed RNA polymerase 2a, protein 2a.
What is the protein family that this protein belongs to?
Belongs to the ssRNA positive-strand viruses RNA-directed RNA polymerase family.
Protein: PURP_METJA
Sequence: MISKDEILEIFDKYNKDEITIATLGSHTSLHILKGAKLEGFSTVCITMKGRDVPYKRFKVADKFIYVDNFSDIKNEEIQEKLRELNSIVVPHGSFIAYCGLDNVENSFLVPMFGNRRILRWESERSLEGKLLREAGLRVPKKYESPEDIDGTVIVKFPGARGGRGYFIASSTEEFYKKAEDLKKRGILTDEDIANAHIEEYVVGTNFCIHYFYSPLKDEVELLGMDKRYESNIDGLVRIPAKDQLEMNINPSYVITGNIPVVIRESLLPQVFEMGDKLVAKAKELVPPGMIGPFCLQSLCNENLELVVFEMSARVDGGTNSFMNGGPYSFLYNGEPLSMGQRIAREIKMALQLDMIDKIIS
What is the function of this protein?
Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates.
What are the official names of this protein?
5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase, 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate--formate ligase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: CCA1_SCHPO
Sequence: MASSSSILELNETEKELSDIFLNVSKKIGQMDRKEPEVRFAGGWVRDKLLRIESHDIDVAIDCMSGFEFAQHLQSYLAQQHPDWETKVIKIDANPLKSKHLETATARIMGMDIDIVNLRHHDYTNSNSSNKLVFGTPLEDALRRDATINALFYNLKSKTVEDFTGKGLVDLSNKIIRTPLVADETFGDDPLRAVRCIRFATKYDFNIHEETIKGLKNPELHERLRSSISRERIGVEVDKMLKHCNTNRALKIIHSLGMFACIFGPLEIHTKKLQSKNIESLSLIPYAIDLFGYLQKKDVSIKNLSSSSKYIFWLAIATLPWYNWSILEKSKIKILPPILIRDSLKYSKPIMSQVENFFVHYPLIMSKINVLEKEGKLTRLGCGRLVRELGPHWRDIIDWAFFMNTLISNSDIQRLNKDEEVTWFHVLVKHIEEYGMEEAYNIQPIINGNEITRILGIRPGPHLRKMLDDSIEWRIQNPESTKEDYIAIMLEKGTSAVVDS
What is the function of this protein?
tRNA nucleotidyltransferase involved in the synthesis of the tRNA CCA terminus.  In contrast to what is usually observed in eukaryotes for which one enzyme synthesizes the whole tRNA CCA terminus, in S. pombe, cca1 specifically adds two cytidine residues to a tRNA substrate lacking this sequence while cca2 specifically adds the terminal adenosine residue thereby completing the CCA sequence.
What are the official names of this protein?
tRNA nucleotidyltransferase cca1, CC-adding enzyme cca1, tRNA cytidyltransferase cca1.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
Protein: DXS_ARTS2
Sequence: MGILDTIRNPQDLSKLTEEQLSQLAAEVRSFLIGNVSQTGGHLGPNLGVVELTMAVHRIFDSPRDSIVFDTGHQSYVHKLLTGRQDFSTLRQEGGMSGYPDRGESEHDIVESSHASSSLSWADGISRARQLTGDGDRYVIAVVGDGALTGGMAWEAINNIAADKRRRVVIVVNDNGRSYAPTVGGFADYLASLRPTIDSFRAAPAYEGTLDWWKRKLQNGGPVGQFTYRSLHAMKKGIKDWWAPQGMFEDLGMKYIGPVDGHNLQAMEHALSTAKNYAGPVIVHAMTEKGHGYAPARAHEADQFHAVGIIDPETGVPTEAGGAQSWTSVFADEIAAIADERKDIVGITGAMLIPVGLHKFAARHPERVFDVGIAEQHALTSAAGMAFGGLHPVVAVYATFLNRAFDQLLMDVALHKAGVTIVLDRAGVTGPDGASHHGMWDMAMVQIVPGLHLAAPRDATRLREELREAVAIEDAPTVVRYSKGNVGAEVEALERLSDGVDVLARRPAGSSENDVLIVSVGAMSELALDVSNRLGAQGISSTVVDPRWLLPVRKSIIALAARHRLVICIEDGVRAGGVGSRIRQEMRAAGVDTALNEVGLPVEFLDHGTRAQVLERVGLTARQITHDVVAQVLGTKVPFARPLPGQEHPTTGSLPKL
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: LIPB_POLSJ
Sequence: MNMEIRHLGRVDYLPTYEAMQAFTLERTAATPNSLWICEHPPVYTQGLAGKIEHVLNPGDIPVVQTNRGGQVTYHGPGQVVAYPLIDLKQAGYYVKEYVYRIEEAVIRTLSHFGVTGHRVPGAPGIYVRLDDPFSHARLRPSPQPSPKGRGSSTPVLLPPLPGEGGGGGGPDPDPFHSLGKIAALGIKVSRHCTYHGVALNVAMDLEPFSRINPCGYAGLKTVDLRTIGVSVTWQEAADVLGQKLSSYLAP
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YMGG_ECO24
Sequence: MKKKILAFGLISALFCSTPAMADMNRTTKGALLGAGVGLLTGNGVNGVLKGAAVGAGVGAVTEKGRDGKNARKGAKVGAAVGAVTGVLTGNGLEGAIKGAVIGGTGGAILGKMK
What are the official names of this protein?
UPF0757 protein YmgG.
What is the protein family that this protein belongs to?
Belongs to the UPF0757 family.
Protein: MIAA2_PHOV8
Sequence: MEKYDLITILGPTASGKTPLAAALAYKLDTEIISGDSRQVYRRMDLGTGKDLEDYVVNGQQIPYHLIDIVDPGYKYNVFEFQRDFLNAYDQVRWKDKLPILCGGTGMYLESVLKGYRLLPVPENPKLRDSLADKSLAELTRLLSTYRKLHNSTDVDTVKRAIRAIEIEEYYKHQSAEYREFPQIHSLIIGVDIARELRREKISHRLKQRLDEGMVNEVKALLDSGISSEDLIYYGLEYKYLTLYVLGKLSFNEMFHQLEIAIHQFAKRQMTWFRGMERRGFTIHWLDACLPMEDKVEKIINLLHTKN
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase 2, Dimethylallyl diphosphate:tRNA dimethylallyltransferase 2, DMAPP:tRNA dimethylallyltransferase 2, DMATase 2, Isopentenyl-diphosphate:tRNA isopentenyltransferase 2, IPP transferase 2, IPPT 2, IPTase 2.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: VG47_ICHVA
Sequence: MIASIVFFIVLVDGVATGSPNALVTDFDCRPGMKHCGVCQQLISGSTGANALCSYKGVGDFIVNNFSMGPVDWLWPSTAPSYAVVSESWGCVDDGAAFCDTTGNFRDHRGRVAREGRDGLGTVLIRPAGNGGPIDDCGADGFTQAIGTVVTTVTDYTRSERCAAVLVTVPPPNETVWYDGKCGFIPSSSSAAPPILGNMLLALIRAHPTLTLRMIQRILVRAAKPVTVTGWRGRGWWLNRVTDRWTHRNFGFGEVSPSRLEIEARRELSTSRAPVAWSTLDTCDLSEVEWVRVRLGIAPAVFRGGVTVEISSPSGTIIEILGKRPLDFSRDEFEGEFVTPFWGEPGRGKWTVSCTGGVILTTEGTCHGIR
What are the official names of this protein?
Subtilisin-like protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
Protein: RSMJ_ECO27
Sequence: MKICLIDETGAGDGALSVLAARWGLEHDEDNLMALVLTPEHLELRKRDEPKLGGIFVDFVGGAMAHRRKFGGGRGEAVAKAVGIKGDYLPDVVDATAGLGRDAFVLASAGCRVRMLERNPVVAALLDDGLARGYADAEIGGWLQERLQLIHASSLTALSDITPRPQVVYLDPMFPHKQKSALVKKEMRVFQSLVGPDLDADGLLEPARLLATKRVVVKRPNYAPPLANVATPNAVVTKGHRFDIYAGTPV
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRAP_MOUSE
Sequence: MESVALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGAEGFVPKNYIRVKPHPWYSGRISRQLAEETLMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYFLWEEKFNSLNELVDFYRTTTIAKRRQIFLCDEQPLIKPSRACFAQAQFDFSAQDPSQLSLRRGDIVEVVEREDPHWWRGRAGGRLGFFPRSYVQPVHL
What is the function of this protein?
Couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.  Plays a role in the inner ear and in hearing.
What are the official names of this protein?
GRB2-related adapter protein.
What is the protein family that this protein belongs to?
Belongs to the GRB2/sem-5/DRK family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Synapse. Note=Localizes at the presynaptic terminal.