PharMolix/UniProtQA huggingface dataset:
Protein: CEP97_XENLA
Sequence: MAVAHLACDSQGSVVDLSGQGLQKLSPTLPFGNDTQTLILDKNQIIKLEHVEKCRNLVQLSVANNRLVRMMGVAKLIHLRVLNLPHNSIGYVEGLKDLVHLEWINLAGNNLKIIDQINSSTSLQHLDLSDNNISQIGDLSKLKSLKTLLLHGNNIASLRAASACLPQSLTILSLAENEIRDLNEVAFLAGLVDLEQLSIMNNPCVMATPSIPGFDYRPFIVSWCLNLKVLDGYVVSQKESLKAEWLYSQGKGRSYRLGQHIPLVQYLATVCPLTSAHGLQTEEDAKLDKILSKQRLHQKQLLHQTRSDGYLTSSTPNKRLPLSTEHHSPTHVLQTEPTVQVNNWLRSSSSEDHSYAVRNICSSPFGPPHYSSLYMEDIQTDEDKLNCSLLSSESTFMPVAPGLSPVSPTVELRVPAIKADLPVNETVIEFNKDHTELPPSETPEKPKLIPGLSAMQDDKSCCVYPVIKDENVTENIINCETAVSMESTQTSNGPTCHNLIMNCKQASVLDQDVNHINKISKAATKLQSCWRGFYARKYNPKVKDVCYEIRLSRMQEHIVFLTEEVIRLRKEKEEDRIQRILQGEAVRYLWEQVQAIQQWQNTVKLQTANSSENDLPSASNSKHANPALEELPSSPEKLNRKASPDIPDSGFHSVILNHCTMGNTEKNSSEESEYSQPSLDTGRHYNDKVPDSPADQDLTREEQSQSSKDSFTSEQDSSLLQQYLRSVEQLDETADNTSYSERTEESRPEITTCSDNSDLSCSISHFLPENSKQENIDIHSNLPSIDDGHNTPIPCDSSLLVPQPDLV
What is the function of this protein?
Acts as a key negative regulator of ciliogenesis in collaboration with ccp110 by capping the mother centriole thereby preventing cilia formation.  Required for recruitment of ccp110 to the centrosome (By similarity).
What are the official names of this protein?
Centrosomal protein of 97 kDa, Cep97, Leucine-rich repeat and IQ domain-containing protein 2.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: QUEF_YERPB
Sequence: MSSYQNHKALAELTLGKPTAYCDHYDATLLQAVPRSMNREPLGLYPDNLPFHGADIWTLYELSWLNSNGLPQVAVGEISLNADSINLIESKSFKLYLNSFNQTIFADKESVRMTLQRDLAACAQGNVSVALYDLDEITGQPISNFNGECLDKQDIRIDSYEFNADYLQGAAGKDHVEESLVSHLLKSNCLITHQPDWGSVQIHYRGPQIDHEALLRYLVSFRHHNEFHEQCVERIFNDIMRFCQPETLTVYARYTRRGGLDINPWRSNTDFVPLTGRLARQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBPA1_RAT
Sequence: MKRLLILSLLLEAVCGNENFVGHQVLRISAADEAQVQKVKELEDLEHLQLDFWRDAARAGIPIDVRVPFPSIQSVKAFLEYHGISYEIMIEDVQLLLDEEKQQMSAFQARALSTDSFNYATYHTLDEIYEFMDLLVAEHPQLVSKIQIGNTFEGRPIHVLKFSTGGTNRPAIWIDTGIHSREWVTQASGVWFAKKITKDYGQDPTFTAVLDNMDIFLEIVTNPDGFAYTHKTNRMWRKTRSHTQGSLCVGVDPNRNWDAGFGMAGASSNPCSETYRGKFPNSEVEVKSIVDFVTSHGNIKAFISIHSYSQLLLYPYGYTSEPAPDQAELDQLAKSAVTALTSLHGTKFKYGSIIDTIYQASGSTIDWTYSQGIKYSFTFELRDTGLRGFLLPASQIIPTAEETWLALLTIMDHTVKHPY
What is the function of this protein?
Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro (By similarity).  Catalyzes the conversion of leukotriene C4 to leukotriene F4 via the hydrolysis of an amide bond (By similarity).
What are the official names of this protein?
Carboxypeptidase A1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Secreted.
Protein: APCB_SYNY3
Sequence: MQDAITAVINSADVQGKYLDGAAMDKLKSYFASGELRVRAASVISANAATIVKEAVAKSLLYSDVTRPGGNMYTTRRYAACIRDLDYYLRYATYAMLAGDASILDERVLNGLKETYNSLGVPISSTVQAIQAIKEVTASLVGADAGKEMGVYLDYICSGLS
What is the function of this protein?
Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex.  Allophycocyanin has a maximum absorption at approximately 650 nanometers.
What are the official names of this protein?
Allophycocyanin beta chain.
What is the protein family that this protein belongs to?
Belongs to the phycobiliprotein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=Forms the core of the phycobilisome.
Protein: MUTH_KLEP3
Sequence: MPTIAPLSSPPQSQEQLLAQARQLAGYSLGELAALAGIPIPRDLKRDKGWTGILLELWLGASAGSKPEQDFAALGVELKTIPIDSRGRPLETTFVCVAPLTGNSGVTWESSHVRHKLQRVLWIPVEGERTIPLAARRVGAPLLWSPDEDEERQLRMDWEELMDLIVLGEVERITARHGEVLQLRPKAANSKALTEAIGAHGETILTLPRGFYLKKNFTAALLARHFLLQHD
What is the function of this protein?
Sequence-specific endonuclease that cleaves unmethylated GATC sequences.  It is involved in DNA mismatch repair.
What are the official names of this protein?
DNA mismatch repair protein MutH, Methyl-directed mismatch repair protein.
What is the protein family that this protein belongs to?
Belongs to the MutH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRHO_STRPS
Sequence: MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADEGINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEENEQAFKKMFVRYKKEIVHLGLEDNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRNFRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKDPEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILTSEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: PYRB_YERPN
Sequence: MANPLYHKHIISINDLSRDELELVLRTAASLKKTPQPELLKHKVIASCFFEASTRTRLSFETSIHRLGASVVGFSDSSNTSLGKKGETLADTMSVISTYVDAIVMRHPQEGASRLAAQFSGNVPIVNAGDGANQHPTQTLLDLFTIQETQGRLDNINIAMVGDLKYGRTVHSLTQALAKFNGNHFFFIAPDALAMPAYILQMLEEKEIEYSLHESLEEVVPELDILYMTRVQKERLDPSEYANVKAQFILRSSDLTGARDNLKVLHPLPRIDEITTDVDKTPYAYYFQQAGNGIFARQALLALVLNAELAL
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: RF3_SALPA
Sequence: MTLSPYLQEVAKRRTFAIISHPDAGKTTITEKVLLFGQAIQTAGTVKGRGSSQHAKSDWMEMEKQRGISITTSVMQFPYHDCLVNLLDTPGHEDFSEDTYRTLTAVDCCLMVIDAAKGVEDRTRKLMEVTRLRDTPILTFMNKLDRDIRDPMELLDEVENELKIGCAPITWPIGCGKLFKGVYHLYKDETYLYQTGKGHTIQEVRIVKGLNNPDLDAAVGEDLAQQLRDELELVQGASNEFDEELFLAGEITPVFFGTALGNFGVDHMLDGLVAWAPAPMPRQTDTRTVEASEEKFTGFVFKIQANMDPKHRDRVAFMRVVSGKYEKGMKLRQVRTGKDVVISDALTFMAGDRSHVEEAYPGDILGLHNHGTIQIGDTFTQGEMMKFTGIPNFAPELFRRIRLKDPLKQKQLLKGLVQLSEEGAVQVFRPISNNDLIVGAVGVLQFDVVVARLKSEYNVEAIYESVNVATARWVESADAKKFEEFKRKNETQLALDGGDNLTYIAPTMVNLNLTQERYPDVQFRKTREH
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR7_PSEPW
Sequence: MEKREELYRGKAKSVYKTDDADRLILLFRNDTSAFDGKRIEQLDRKGMVNNKFNAFIMQKLEEAGVPTQFDKLLGDNECLVKKLDMIPVECVVRNYAAGSLVKRLGVEEGIKLEPSTFELFLKNDEKGDPFINESHVVAFGWGTAEQLAEMKKLSLKVNEVLNKLFDDAGLLLVDFKLEFGVFHGQIVLGDEFSPDGCRLWDKETRKKMDKDRFRQGLGDVIEAYEEVAKRLGVPL
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: COX1B_STRCO
Sequence: MVVGLSPRRLGTLRRMAVDRRTKSPRRTPARQRTNRTLGRALVRWATTTDHKVIGHLYLATSFGFFLLGGVLAMLMRSELARPGLQLFSNEQYNQLFTVHGTIMMLLFATPLFAGFTNVIMPLQIGAPDLAFPRLNALSYWMYLFGGLMVVSGFLTPGGAASFGWFAYAPLNSATFSPGPGGDLWTMGLVVSGVSTTLSAVNFISTIICLRAPGMTMFRMPIFTWNILFTSILVLPAFPVLTAALLMLEADRKFGAHVFDAANGGALLWQHLFWFFGHPEVYIVALPFFGIVTEIIPVFSRKPIFGYVSLVGATIAITFLSAVVWAHHMFATGAVLLPFFSLMSFLIAVPTGVKFFNWIGTMIRGSLSFETPMLWACGFLVTFLLGGMSGVLIASPPLDFHLTDSYFIVAHLHYVLFGTVVFAMFAGFYFWWPKFTGKLLDERLGKIHFWTLFVGFQTTFLVQHWLGEQGMPRRYADYLAADGFTTLNTISSIGAFLLGLSTLPFLYNVWRTHQYGEKVGRDDPWGYGRSLEWATSSPPPRHNFTSLPRIRSESPAFDLHHPDVTRHDQRHVQ
What is the function of this protein?
Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Subunits 1-3 form the functional core of the enzyme complex.  CO I is the catalytic subunit of the enzyme.  Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B (By similarity).
What are the official names of this protein?
Putative cytochrome c oxidase subunit 1-beta, Cytochrome aa3 subunit 1-beta, Cytochrome c oxidase polypeptide I-beta.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GCSH_SALPK
Sequence: MSNVPAELKYSKEHEWLRKEADGTYTVGITEHAQELLGDMVFVDLPEVGATVSAGDDCAVAESVKAASDIYAPVSGEIVAVNDALSDSPELVNSEPYAGGWIFKIKASDESELESLLDATAYEALLEDE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: HAKAI_DROME
Sequence: MDTEEVKRGRGRGRGTRARGRGRGRGRGRGKKIDDSSIADAAALAASSCAALEDSPGRLDASEDSVMQELDKDGELETPGALEEPLPHGALGAVAASGNMTPATQQPQVLQQVPPPVMSQTTISLSLARAVDMEADISQLEAPTFTTLSRGPPEPMLRLKWNHKVSLIGEKVLNPMIHCCDQCDKPILVYGRMIPCKHVFCLKCARAEPIKSCPRCTDKVLRVEQSGLGTVFMCTHGGSRYGSSGCRRTYLSQRDLQAHINHRHVAPQPPPLQPQPQLSAMAEQPKMTDLGGVGLGLELHKQRKLSESSVPISVSASIASRPVLSRLPLTGGVGNIGSIGSIPPPGSAAAAQNAIHGGHSTLTLANLTRINNANAQECHQGKASLHHTLKKGTPHQSESVADASYYSSVLASFGSAAGNPGSGPPGGGATAAAQPANPSGSHSAVGPGALIGGSTDAPTGGSSGNWQQSQYYR
What is the function of this protein?
E3 ubiquitin-protein ligase required during early development (PubMed:19682089).  E3 ubiquitin-protein ligases mediate ubiquitination of target proteins (PubMed:19682089).  Required for epithelial integrity and midgut morphogenesis (PubMed:19682089).  Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing (PubMed:29535189).  Its function in the WMM complex is unknown (PubMed:29535189).
What are the official names of this protein?
E3 ubiquitin-protein ligase Hakai.
What is the protein family that this protein belongs to?
Belongs to the Hakai family.
What are the subcellular locations of this protein?
Nucleus. Cell membrane. Cytoplasmic vesicle. Cytoplasm, perinuclear region.
Protein: PRMA_ACIB5
Sequence: MKWLQIHITVDQEQVEFTETLLMSLGAVSVTLDDAEDQALLEPLPGETPLWNKVIVTGIYQQDEQDPIDVDTLEAFLKAQLPDVPMRHEELEDQVWERAWMDYYEPIQIGEKFWIVPEWLEPPEADATNIKLDPGLAFGTGNHASTFLCLQWLGKTDVKDKIVIDYGCGSGILGVAALLLGAKKVYATDIDPQAVLATKQNAELNGVLDRLYVGLPEEFDQEFKPQQADVLVANILAGPLMALAPEFAKLLKSDGDFALAGVIEEQVADVSGVYSEFFDILDVEKREENWCRISGKRKTTN
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DESI2_PONAB
Sequence: MGANQLVVLNVYDMYWMNEYTSSIGIGVFHSGIEVYGREFAYGGHPYPFSGIFEISPGNASELGETFKFKEAVVLGSTDFLEDDIEKIVEELGKEYKGNAYHLMHKNCNHFSSALSEILCGKEIPRWINRLAYFSSCIPFLQSCLPKEWLTPAALQSSVSQELQDELEEAEDAAASASAASTAAGSRPGRHTKL
What is the function of this protein?
Has deubiquitinating activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.  Deubiquitinates 'Lys-48'-linked polyubiquitination of RPS7 leading to its stabilization.
What are the official names of this protein?
Deubiquitinase DESI2, Desumoylating isopeptidase 2, DeSI-2, PPPDE peptidase domain-containing protein 1, Protein FAM152A.
What is the protein family that this protein belongs to?
Belongs to the DeSI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRA_STRP6
Sequence: MERAIFAGGCFWCMVQPFEEQAGILSVRSGYTGGHLPNPSYEQVCAKTTGHTEAVEIIFDPEEISYKELVELYWAQTDPTDAFGQFEDRGDNYRPVIYYTTERQKEIAEQSKANLQASGRFDQPIVTTIEPAEPFYLAEDYHQGFYKKNPKRYAQSSAIRHQFLEENWS
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: S35G3_MOUSE
Sequence: MAASHPYFNLPDFTQPSPPSTPASLPSKHHHRCGPSNATKGLFVALLGGGLSAGFVGPFSRMAYQTSQLPSLELLIFRCLFHLPIALLLKFRGDPLLGPPDVRVRAFLHAILNVLSIGCAYSAVQVVPAGNAVTVRKGSSTVCSALLALCLESQGLSGYAWCGLFGSTLGLIIIVGPGLGTLQEGTTGLYTALGYVLAFLGGLALSLGLQIYRSLHFPSCLPTVAFLFGLVGLMVSVPGLFVLQTPVLPQDTLSWSCVVAVGLLALVSFVCVSYAVTKAHPALVCAVLHSEVVVALMLQYYVLYETVAPSDIMGAGVVLGSIAIITAQNLSCDKEGQTEE
What are the official names of this protein?
Solute carrier family 35 member G3, Acyl-malonyl-condensing enzyme 1.
What is the protein family that this protein belongs to?
Belongs to the SLC35G solute transporter family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MBR1_YEAS1
Sequence: MRMEKTTDKPLSAGDMNDEYSRGPIDDIDCLNFFERAVQDPCCEACDTEDADEELRAKLSSFNFQPDSSPCNAKCQQTLNPLCKIDEGLPAESELAPSRNGSVSEANSDTNSIASTVHDPVDSKYGGMPSLRKAKTTSYFTSSSSNNTTMRNPLKKCNTNINGLLVNRRSSSSSRQSIPELFSGACTKKKNNVLLKSETPNSEFSTNSLQHCNSRSFSLPRSRSRSSAIAIPTHLYGLEKYVSPELDTLTADPEESIERFSNNRPREISSCCPNDTGDTSSSLSHSNTSSSLNFPLGTNTNQFHQPRQPVQQQQSSKPNFGAGRKKSFIEMSLASSFAG
What is the function of this protein?
Participates in mitochondrial biogenesis and stress response.
What are the official names of this protein?
Mitochondrial biogenesis regulation protein 1.
What is the protein family that this protein belongs to?
Belongs to the ISF1/MBR1 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MATRX_BDV1
Sequence: MNSKHSYVELKDKVIVPGWPTLMLEIDFVGGTSRNQFLNIPFLSVKEPLQLPREKKLTDYFTIDVEPAGHSLVNIYFQIDDFLLLTLNSLSVYKDPIRKYMFLRLNKEQSKHAINAAFNVFSYRLRNIGVGPLGPDIRSSGP
What is the function of this protein?
Plays a crucial role in virion assembly and budding.
What are the official names of this protein?
Matrix protein, gp18, p16.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Host cell membrane; Peripheral membrane protein. Note=During viral budding, associates with the inner side of the plasma membrane of infected cells (PubMed:11711600). Found in nuclear punctate structures that have been proposed to be the sites of viral replication and transcription, also termed viral speckles of transcripts (vSPOTs) (By similarity).
Protein: SAU62_ARATH
Sequence: MMINAKKLMKLAKKWQQRAALKRKRISFQRSSITTSSQTAVEKGCFVVYTADKIRFSFPLSYLSNTIVQELLKISEEEFGLPTEGPITLPFDSAFLEYLINLIQRRMDEDTEKALLLSISSARSSFQPQQHCSATQQLLVF
What is the function of this protein?
May promote auxin-stimulated organ elongation, such as hypocotyls, stamen filaments and petals.
What are the official names of this protein?
Auxin-responsive protein SAUR62, Protein SMALL AUXIN UP RNA 62.
What is the protein family that this protein belongs to?
Belongs to the ARG7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CHEB_HALH5
Sequence: MESRIKVLVVDDSAFMRKVITSMLESDPRLEVVGTARNGEDALKKRKTLAPDVMTLDVEMPVMDGIETLKRLMSENPLPIIIVSSTTKEGAENALTAMELGAVDFITKPSGPISLDLEKVRDLLIEKVASAPNVKLKPTSKKAPVVFRPLQQPVPFDKTIIVIGTSTGGPKALKQVLTKLPKDLPAPILIVQHMPAGFTESLANRLNSLCEIHVKEAEDGEIIRPGVAYIAPGGYHLETKRLGTSIALHLTKEEPRKGHRPSVDVLFESVSALSSIYKVAVIMTGMGSDGTEGLEQLKRGSCYAIAESEQSCVVFGMPKVAIERKLVDEVTHLELIADSIVRQCKR
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
Protein: YR355_MIMIV
Sequence: MNICGPQRYDKENNTCFNVDQLVEMAKAYNRYLSKTKLNPSRNYHFGDADLINIKSDKKYLLKQFKDRFGKICGSDEICLTHQAFMGELVGEMKDDILFGTFRSEGPSKSTEWLSTIDINQIMVPYENIYPNFKFIGAVPADCDQVSVCPLYNINYDKLMDEGINYIATIFNHDRYGQPGSHWVAMFVDINNGKLYYCDSNGKEPTKYIENSIEKFAQFYKRKTGNDIIYKYNKNSYQKDGSECGVYSCNFIIRMLSGEPFDNIVSNSLSFQEINSCRNVYFRNQPSKFKPHKLCDPTNSGK
What are the official names of this protein?
Putative thiol protease R355.
What is the protein family that this protein belongs to?
Belongs to the peptidase C48 family.
What are the subcellular locations of this protein?
Virion.
Protein: RU1C_PLABA
Sequence: MPKYYCEYCDIYLTHSSPVGRRQHNQGRKHISAKIEYFQNLLREEGITPQNFLGFLGNQGYNNTLANPMMNNFMPGNYNAYMKYNPMRNYHHSNRNSNYQHSIGMHNNKYSRAGYVPPGSNKYPNNHFHNNKRINNIPKPYNNYTNKPITNSSYKNDKQDYRNNNESNDNMNSNNFSNYQVNKENANFVNKNNEQPN
What is the function of this protein?
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome.  U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing.  The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA.  Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
What are the official names of this protein?
U1 small nuclear ribonucleoprotein C, U1 snRNP C, U1-C, U1C.
What is the protein family that this protein belongs to?
Belongs to the U1 small nuclear ribonucleoprotein C family.
What are the subcellular locations of this protein?
Nucleus.
Protein: VATA_CLOP1
Sequence: MKTGKIIKVSGPLVVAEGMDEANVYDVVKVGEKGLIGEIIEMRGDKASIQVYEETSGIGPGDPVITTGEPLSVELGPGLIESMFDGIQRPLDAFMKAANSAFLSKGVEVKSLNREKKWPFVPTAKVGDKVSAGDVIGTVQETAVVLHRIMVPFGVEGTIKEIKAGDFNVEEVIAVVETEKGDKNLTLMQKWPVRKGRPYARKLNPVEPMTTGQRVIDTFFPVAKGGAAAVPGPFGAGKTVVQHQVAKWGDTEIVVYVGCGERGNEMTDVLNEFPELKDPKTGESLMKRTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYSVSIMADSTSRWAEALREMSGRLEEMPGDEGYPAYLGSRLADYYERAGKVVALGKDGREGAVTAIGAVSPPGGDISEPVTQSTLRIVKVFWGLDAQLAYKRHFPSINWLTSYSLYLEKMGEWMDAHVADDWSALRTEAMALLQEEANLEEIVRLVGMDALSEGDRLKLEVAKSIREDYLQQNAFHENDTYTSLNKQYKMLNLILSFKHEAEKALEAGVYLDKVLKLPVRDRIARSKYISEEEISKMDDILVELKSEMNKLISEGGVLNA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type alpha chain is a catalytic subunit.
What are the official names of this protein?
V-type ATP synthase alpha chain, V-ATPase subunit A.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: MICU1_CAEEL
Sequence: MLHCSFLRVIPIKNASKRLIIVRSLTSAPAKTSEAEKQQDSLKNIDAGEKYTALGNIRQKKDVFHYTDRASGVGYSHYSSSVYQHRPYIWPPLRKLYHWNYALVIAGMVILMSDFEWLKDQIKSASLPFRPEASQKEEVTESNGEVEEVKEKPKKKKLGFRERRIIEYEDRLRLYSTPDKIFRYFATLKIIDPNEDSGRFEVFMTPEDFLRSFTPGVMQPRRWGLDSFKNYNPEKHKRHKFSDPDSIFYKLGENGLINFSDYLFLMTLLSTSHADFALAFKIFDVDGNGALDKEEFTKVQQLIMSQTTVGQRHRDHITPNQSFRVETNSALETYFFGKDGKGSLSSEKFIEFQERLQHDILKMEFERRDALDNPDGLINEDSFAQLLLLHAQINEKKQKHMLKRVKRRFKGENLKGISFGETKAFFEFLYHIDDVDIALHFHKMAGMSIDAKLLQRVAVKVTGIPLSDHVVDVVITLFDDNLDGKLSHEEMVAVMRRRMRRGLERPRDTGLFRLFDAVLECGKRAYHASPLPFY
What is the function of this protein?
Key regulator of mitochondrial calcium uniporter (MCU).  Modulates the activity of the mitochondrial calcium uniporter protein mcu-1 depending on the level of intracellular calcium in PLM touch receptor neurons following axonal injury (PubMed:31983639).
What are the official names of this protein?
Calcium uptake protein 1 homolog, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the MICU1 family. MICU1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein. Mitochondrion intermembrane space. Note=The topology is subject to debate.
Protein: VATE_METM5
Sequence: MGAEKITSKIVEDANKNAEKILAEALNEKEAILTEAKEEASTKEQAIAKKGEKDAEMTKNRILAEARLSAKKKLLEEREKTIQLTLEKLEEDLVKLPQKEEYKDILLKMIISGVYSVGGGELELLLNKKDFEIIDDSTLWALEKEMEDRLKKVTVLKKGEAKSIIGGCIIKTADQTKVSDNSLEATFERNLDSVRAKIAEMLF
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: SSU1_YEAST
Sequence: MVANWVLALTRQFDPFMFMMVMGVGISSNILYSFPYPARWLRICSYIMFAIACLIFIAVQALQILHLIVYIKEKSFREYFNDFFRNMKHNLFWGTYPMGLVTIINFLGALSKANTTKSPTNARNLMIFVYVLWWYDLAVCLVIAWGISFLIWHDYYPLEGIGNYPSYNIKMASENMKSVLLLDIIPLVVVASSCGTFTMSEIFFHAFNRNIQLITLVICALTWLHAIIFVFILIAIYFWSLYINKIPPMTQVFTLFLLLGPMGQGSFGVLLLTDNIKKYAGKYYPTDNITREQEILTIAVPWCFKILGMVSAMALLAMGYFFTVISVVSILSYYNKKEIENETGKVKRVYTFHKGFWGMTFPMGTMSLGNEELYVQYNQYVPLYAFRVLGTIYGGVCVCWSILCLLCTLHEYSKKMLHAARKSSLFSESGTEKTTVSPYNSIESVEESNSALDFTRLA
What is the function of this protein?
Involved in efflux of free sulfite.  Mutations in the SSU1 gene cause sensitivity to sulfite.
What are the official names of this protein?
Sulfite efflux pump SSU1, Sulfite sensitivity protein SSU1.
What is the protein family that this protein belongs to?
Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ADE_CAUVN
Sequence: MTDASFAPSASAEFVRGLPKAELHMHIEGSLEPELMFELAQRNGITLPFASVEEIRAAYDFSNLQDFLDIYYQGAGVLITEADFKDLALAYFQRLAADGGAHAEIFFDPQTHTDRGIAFDTVMNGLLAGMDEAEKTLGVTSKLILCFLRHLSEEAAFETLEQAKPWLAKLAGVGLDSSEVGHPPAKFARVLQASRDLGLKVVAHAGEEGPPAYVWEAIDLVKVDRIDHGNRALEDEALTARLVKDGITLTVCPLSNLKLCGVPSLDVHPLKRMLDLGLKATVNSDDPAYFGGYLLENYLATADAVGLTRDDIVTLAKNSFAGSFLTDAEKAQRIAAVEAYAAAH
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenine to hypoxanthine.  Plays an important role in the purine salvage pathway and in nitrogen catabolism.
What are the official names of this protein?
Adenine deaminase, ADE, Adenine aminohydrolase, AAH.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
Protein: PTH_RUEST
Sequence: MKLFVGLGNPGAKYAGNRHNIGFMALDQIASDHGFSPWKSKFQAQMSEGTLSGEKVILLKPQTFMNNSGQSVGEALRFFKLTPADVVVFHDELDLAPSKCRVKNGGGHAGHNGLRSIHAHIGADYGRVRLGVGHPGHKDAVAGYVLRDFPKADQGWLDDLMRGLSDGAAALATGDSGRFMNAVALRVAPPRSSTGEASKGRKKAQKSEPGVAKTPAKAATPEAPAAGDIPAAPEDSRSPMQKLLDKFK
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SNAPN_YEAS8
Sequence: MAGDSISADGTGVHPVELSVYSVLSTDLDGLYQSINELRESQALLILMLRKVRDKLRREGQVLYDPEPFKPTMDKLADLSARVRILSQRYEELQGNARALNN
What is the function of this protein?
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1), a complex involved in endosomal cargo sorting.
What are the official names of this protein?
Biogenesis of lysosome-related organelles complex 1 subunit SNN1, BLOC-1 subunit SNN1, SNAPIN-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the SNAPIN family.
What are the subcellular locations of this protein?
Endosome.