PharMolix/UniProtQA huggingface dataset:
Protein: ANDR_HUMAN
Sequence: MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLLLLQQQQQQQQQQQQQQQQQQQQQQQETSPRQQQQQQGEDGSPQAHRRGPTGYLVLDEEQQPSQPQSALECHPERGCVPEPGAAVAASKGLPQQLPAPPDEDDSAAPSTLSLLGPTFPGLSSCSADLKDILSEASTMQLLQQQQQEAVSEGSSSGRAREASGAPTSSKDNYLGGTSTISDNAKELCKAVSVSMGLGVEALEHLSPGEQLRGDCMYAPLLGVPPAVRPTPCAPLAECKGSLLDDSAGKSTEDTAEYSPFKGGYTKGLEGESLGCSGSAAAGSSGTLELPSTLSLYKSGALDEAAAYQSRDYYNFPLALAGPPPPPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGDLASLHGAGAAGPGSGSPSAAASSSWHTLFTAEEGQLYGPCGGGGGGGGGGGGGGGGGGGGGGGEAGAVAPYGYTRPPQGLAGQESDFTAPDVWYPGGMVSRVPYPSPTCVKSEMGPWMDSYSGPYGDMRLETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ
What is the function of this protein?
Lacks the C-terminal ligand-binding domain and may therefore constitutively activate the transcription of a specific set of genes independently of steroid hormones.
What are the official names of this protein?
Androgen receptor, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Detected at the promoter of target genes (PubMed:25091737). Predominantly cytoplasmic in unligated form but translocates to the nucleus upon ligand-binding. Can also translocate to the nucleus in unligated form in the presence of RACK1.
Protein: GUAA_METFK
Sequence: MQQKILILDFGSQYTQLIARRIREANVYCELHSWDVSDAFIREFNPAGVILSGGPNSVYEDETPRAPQSVFELGVPVLGICYGMQTMAAQLGGSVENAAKREFGYAEIRAQGHSALLKGIQDKSNAEGHGLLDVWMSHGDKVTALPEGFKIIASNSATPIAGMADENRRFYAVQFHPEVTHTKQGKALLNRFVHDICGCDQSWNMPDYVETAVQRIREEVGCDEVILGLSGGVDSSVAAALIHRAIGDQLTCVFVDNGLLRLNEAEQVMETFGKNLGVKVIHVDASAKFLGDLSGVNDPEAKRKIIGREFVEVFQQEAAKLPQAKWLAQGTIYPDVIESAGAKTKKAHTIKSHHNVGGLPDTLKLKLLEPLRELFKDEVRELGIALGLPHDMVYRHPFPGPGLGVRILGEVKREYADLLRQADHIFIEELRSTKDADGKSWYDKTSQAFAVFLPVKSVGVMGDGRTYDYVVALRAVVTTDFMTAHWAELPYDLLGKVSNRIINEVRGINRVVYDISGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: Y184_METJA
Sequence: MNIMITKQFDRHLKYYTTIVKVFANGIILITAYYLVFELPVGYLIGLYIIMFVVWLLVSMFFLGRLLDFMAKMDLKK
What are the official names of this protein?
Uncharacterized protein MJ0184.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: THIG_ALIB4
Sequence: MNDILKIGKYELNSRLIVGSGKYKDFQTTKEATLASGSELITVAIRRVNITNPNEENLLDYFKDTNVKFLPNSAGCFTAEEAITTFRLMREATGIDLIKLEVIGDAQKTLYPDVIETIKACEILKKDGFTIMAYTSDDPIIAKRLEDAGADAIMPLAAPIGSGLGIQNKYNIAFIRDAVKVPVIVDAGIGCASDASIAMELGADAVLANSAIACAQNPIQMAEAMKYAVIAGRLGYKAGRIPKKPYATASSPIDGLIQF
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FUS9_GIBF5
Sequence: MADKSHVNNVPMQGNGAYSSHAALQHEAMLKALPLFQAAAEVIANVDSTRISIVEYGSAHGNNSLEPMEAILKSIPTESLELLFSDRPENDFCTLSKTVTAWADGIVGNQLLNPLFISMIPRSFYQQVVPPKSAHLGFSLAALHHLDHVPQPTEDGQDESELLQQQAHVDLATFLKLRSQEIVSGGSLILSFVSQASAGYENYSGPVDACRNAMIEMVQQGKIPLSVAQAFRVPTYNRTLSDVKKVMDEFTQTWKVHDLFEDDVMHPAFHKLKIQSNPSLEASHKYAEVVIDWMMAVCSGYFTKALQVGSQGGYTKQEEEGLLQVWVTRTKEFFIRDYKDKEVICSFIYIRLERL
What is the function of this protein?
Methyltransferase; part of the gene cluster that mediates the biosynthesis of the mycotoxin fusarin C (PubMed:23932525).  Within the cluster, FUS1, FUS2, FUS8 and FUS9 are sufficient for fusarin production (PubMed:23932525).  The roles of the other FUS members are yet undetermined (PubMed:23932525).  The fusarin C synthetase FUS1 is responsible for the condensation of one acetyl-coenzyme A (CoA) unit with six malonyl-CoA units and the amide linkage of the arising heptaketide and homoserine, subsequently releasing the first intermediate, prefusarin, as an alcohol with an open ring structure (PubMed:23932525).  The cytochrome P450 monooxygenase FUS8 participates in multiple oxidation processes at carbon C-20 and is able to use the FUS1 product as substrate, resulting in formation of 20-hydroxy-prefusarin (PubMed:23932525).  This reaction seems to be essential before the 2-pyrrolidone ring closure can be catalyzed by FUS2, generating 20-hydroxy-fusarin (PubMed:23932525).  FUS8 is able to further oxidizes carbon C-20 after ring closure, resulting in the formation of carboxy-fusarin C (PubMed:23932525).  As the last step, FUS9 methylates the hydroxyl group at C-21 to generate fusarin C (PubMed:23932525).  Fusarin C can then rearrange to epi-fusarin C, the (z)-isomers, and fusarin A and fusarin D (PubMed:23932525).
What are the official names of this protein?
Methyltransferase FUS9, Fusarin biosynthesis protein 9.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Type-7 methyltransferase family.
Protein: TRMD_CAMC5
Sequence: MKFTFVTLFENLVKPYFNDSILARAVENNKIDVNFINPRDHTTQKHFKVDEYMIGGGAGLLMMPQPLNDTLKKIKENDPDVHIVFLTPAAKKFNQKDAKRLAGKKHICFVCGRYEGIDERIVELWADEVFCVGDFILTGGELGALCLADAIARNIEGVLGNSQSLAIESFEDGLLEAPSFTKPDVFDGNFVVSEFLKGNHAKIRLLKNKMAHCKTRFFRPDLYQKLKPQIKEKHEK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1409_HAEIN
Sequence: MNILDGIKSLALKLGSKQDQTYYARGLSLTDDLMQIEALWRDNWIANKVCIKRSEDMVRNWRDIFSNDLKSEQLDEFTKLERRLKLRETLTKALQWSSLYGAVGLLVVTDTINITSPLQPTERLKRLIILPKWKISPTGQRDDDVFSPNFGRYSEYTITGGTQSVSVHHSRLLIINANDAPLSDNDIWGVSDLEKIIDVLKRFDSASANVGDLIFESKIDIFKIAGLSDKISAGLENDVAHVISAVQSIKSATNSLLLDAENEYDRKELSFGGLKDLLTEFRNAVAGAADMPVTILFGQSVSGLASGDEDIQNYHESIHRLQETRLRPVLEVLDTLLCNELFGGQPDDWWFEFLPLTVVKQEQQVNMLNTFATAANTLIQNGVVNEYQVANELRESGLFANISADDIEEMKNANELARNFEEPEGESTQVQASEDE
What are the official names of this protein?
Uncharacterized protein HI_1409.
Protein: CUYA_ROSNI
Sequence: MHLARFPRRFIAHLPTPLERLDRLSAELGGPEIWIKRDDCTGLSTGGNKTRKLEFLMAEAELQGAEIVMTQGATQSNHARQTAAFAAKLGMKCHILLEDRTGSNEANYNHNGNVLLDHLHGATTEKRPGGGDMNAEMEKLADEWRADGKKVYTIPGGGSNPTGALGYVNCAFELLAQANDGGLKIDHIVHATGSAGTQAGLITGLKAMNAQIPLLGIGVRAPKPKQEENVYNLACATAEKLGCPGVVAREDVVANTDYVGQGYGIPTESGMEAIKMFAELESILLDPVYSAKGAAGFIDLIRKGHFKKGERVVFLHTGGAAALFGYDGAFDFSSRWVG
What is the function of this protein?
Catalyzes the desulfonation and deamination of L-cysteate, yielding pyruvate, sulphite and ammonium.  Involved in sulfolactate degradation.
What are the official names of this protein?
L-cysteate sulfo-lyase.
What is the protein family that this protein belongs to?
Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
Protein: TX22F_PLETR
Sequence: AVKCIGWQETCNGKLPCCDGCVMCECNIMGQNCRCNHPKATSECES
What is the function of this protein?
Potent toxin that may paralyze and/or kill insect pests such as H. virescens (lepidoptera), S. exigua (beet armyworm) and M. sexta (tobacco hornworm).
What are the official names of this protein?
U1-plectoxin-Pt1f, U1-PLTX-Pt1f, Plectoxin XIV, PLT-XIV, PLTXIV, Plectoxin-14.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 02 (plectoxin) family. 02 (plectoxin) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SYA_CLOB1
Sequence: MERMGLNEIREEYLKFFESKAHLRLPSFSLVPKNDKSLLLINAGMAPLKPYFTGLQVPPNKRVTTCQKCVRTGDIENVGKTSRHGTFFEMMGNFSFGDYFKEEVIPWAWEFTTEVLKLPKNKLYVTIYEDDDEALDIWVNKTDMDPKRIFRLGKEDNFWEHGLGPCGPCSEIHFDRGAGEVKTSEEFVKASDEDKIVEFWNLVFTQFDKDEEGNYNKLANPNIDTGMGLERMATIMQNVDTIFEVDTIKAVLDKVCKLSGANYKEDRVKDISIRIITDHIRSITFMISDGILPSNEGRGYVLRRLLRRAARHGKTLGINNTFLHNLTDIVIENCYKNYPELEEKREYIKKIIKLEEERFDETIDAGMQILNDYIKEVKNNNYKILSGDKAFKLYDTYGFPVELTEEILEEEGISIDKEGFNKEMKEQRERARSAREETNYMGAEDTILNKIDLNINTDFEGYDKLEVKSKVAVIIKDEEFKNEMEKGNEGVIVTYNTPFYAEMGGQIGDTGIIYNDNFKAEVIDCKKNISGKILHFVKILDGKVALEDQVILKVNEERRNNIRKNHTATHILHAALIKVVGDHVQQSGSYVDDERLRFDFSHFEAVSEDELKEVEKIVNKEIMKANAVNTKVMNIEEAKQQGAIALFDNKYKDDVRVVSVGDFSKELCGGTHVSNSGQIGIFKIVSEAGVAAGIRRIEAVTAFKAMEYVDHKNNILKEAAQILKCNEKELLNKLNHQVLEMKEKEKEIEALKLKLASGAEDEILDNIKEIKGVKVASAAVKDIDGNALRDLGDKIRDNMQSGVVVLGSNYKGKVLFVAMATKDTVAKGVHCGKIIKEVATIAGGGGGGRPDMAQAGGKDPNKLEDAIKTVETVVESLVK
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TET10_ARATH
Sequence: MGMGTSTFVIRWVNLLTMLLAVAVIIFGVWMSTHNDGCRRSLTFPVIALGGFIFLISIIGFLGACKRSVALLWIYLAVLLIVLIAILVFTVLAFIVTNNGSGHTNPGLRYKEYKLNDYSSWFLKQLNNTSNWIRLKSCLVKSEQCRKLSKKYKTIKQLKSAELTPIEAGCCRPPSECGYPAVNASYYDLSFHSISSNKDCKLYKNLRTIKCYNCDSCKAGVAQYMKTEWRLVAIFNVVLFVVLISSLLSTRFDSEQSFGLLNGLVQISNITFKDCQTTTVPKQF
What is the function of this protein?
May be involved in the regulation of cell differentiation.
What are the official names of this protein?
Tetraspanin-10.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: YI070_YEAST
Sequence: MNNKVTLLPPRVFFCLSWSVMVNIDRRKSDRSVNLDDQHSNKPPSESLISLLSLTSSMSISSLLSLLIIVAVLFPPLYISGLPWIMSFKSVFSFFSLSITSFIMVPFLLISLTILCKIELSSKCITSPSISKFNCPDIINFVNSSLISSKSIPSVDDK
What are the official names of this protein?
Putative uncharacterized protein YIL071W-A.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RIBA_HAHCH
Sequence: MSVTYVASCKLPTPFGVFDMHGFQEVGTQKEHIALTLGDIGDGASVLARTHSECLTGDALFSMRCDCGYQLDEALRSIAAEGRGILLYLRQEGRGIGLLNKIRAYNLQDQGADTVEANEQLGFAADMRDYSMCKPMLYHLGISRIRLMTNNPRKVDSLTKLGIEVVERVPLEVGRNPHNRNYLATKAGKLGHLLTTHQDDDYVVAAK
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: ISPF_SHEAM
Sequence: MKIRIGHGFDVHKFGADRPLILCGIEVPYETGLIAHSDGDVVLHAISDAILGAMALGDIGKHFPDTDAAYEGADSRVLLRHCFKLAREHGFAIGNLDVTIIAQAPKMLPHIEAMRAVLADDLQTELNNINVKATTTEKLGFTGRKEGIAVEAVVLMENVK
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: SHQ1_SCHPO
Sequence: MITPKFELRQDEEFVYLDVHTPYIKAKNVEIDAFNNEVNFCIAPYFLKLELPGNVLDDDRANASYDISSGFVHIKFPKETPGEVFPDLDLLTTLLVNQNKEPVKKPLIEEVEDTPSPSTSQNASKDEEKEVKIDWQNIHFDDPDFDWGLLQRLDDEKMQYTSTSQYGFNNQYSGLLKYNALVGNEINQIPEPERTPPSTRSEIRVQLEDEKFDAEHYMADFYDREMIDEILHYIPDYIGEFLLVQQGKSDRLLEFTSEEKEALAKLPKRSYLIDNPKNVYLCLVPLIFAYAYDNRTTLGDPTIESCWNIGTLSSTISCLDTNFLAIKDIFIACIRRSLAYPLYRNWDLALTCWKDTHAILSLGKRWILRVLLRIRNLFEHHDVYYIYNAIVLNDYAYWIQTANDNVLAALAYQVSECTITKEETNWPLEEIEANVQETIIASDEESESIEK
What is the function of this protein?
Involved in the early biogenesis steps of box H/ACA snoRNP assembly.
What are the official names of this protein?
Protein shq1.
What is the protein family that this protein belongs to?
Belongs to the SHQ1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS2_KARMG
Sequence: MYNIEKFIKVGAHFGHTTSKWNPNMRKYIFMKKGGIHIIDISKTIKKINEACKFIKNIVSSGKKILFVATKKQAKDIVSDYAKKVNMPYITERWLGGILTNMSTIRQSVKKMNVIDRQKIDGTYNMMSKKEKLLIDRLKNKLKKNIGSISKMNSLPACVIIVDVKKEKIAVKECINLCIPIIGIVDTNCDPRNIDYPIPANDDSSKSIHLIISYLTNSILTN
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: CSPL4_PICSI
Sequence: MRKHIDIVFSRLSGPILNPPPDNNVIPKTDRKLRITEVILRFAVVIFALVSAIMVGTASGTRDLGGGIRIHAHFTLLKTLPFLVIVDGILAVYSLLQGLRCFLSLYMRHILLNKALAWTIFCCDQALAYVIFAAAASTAETAYISEQGLDELQWIKVCMFFRAYCFKSGAGMINAFLAALCMVFVSGMSVFHLFRLYGEKRAYGHIAEQVVISEEAAERRNSLNGI
What are the official names of this protein?
CASP-like protein 2BC1, PsCASPL2BC1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DP71L_ASFK5
Sequence: MSRRNKKRSRRRRKKPLNDIQPGPSKSSAQDEPIKSVSHHLSKIGTNPTLAFILGGNEDLSDDSDWDENFSLENTLMPLNEVSLNDKHNSKHFNKGFDNNTALHEVNTKWEAFYSSVKIRQRNVKVHFATDDILVDVREADDIDRKGPWEQAAVDRLRFQRRITDTEEILSTVFLRKKLNPMEHE
What is the function of this protein?
Interacts with the host phosphatase PP1 catalytic subunit (PPP1CB) and recruits it to dephosphorylate EIF2S1/eIF2alpha and therefore restores the host translation that has been shut-down by the host.  Also inhibits the EIF2S1/eIF2alpha-ATF4-DDIT3/CHOP pathway.
What are the official names of this protein?
Protein DP71L, MyD116 homolog.
What is the protein family that this protein belongs to?
Belongs to the asfivirus DP71L family.
Protein: RL29_STAMF
Sequence: MKPDEIRKMTKEERLRRLNELRLELIKLRMQARVGTLTNTARIRNIKRDIARILTIMREEELGISRK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: THI4_ARATH
Sequence: MAAIASTLSLSSTKPQRLFDSSFHGSAISAAPISIGLKPRSFSVRATTAGYDLNAFTFDPIKESIVSREMTRRYMTDMITYAETDVVVVGAGSAGLSAAYEISKNPNVQVAIIEQSVSPGGGAWLGGQLFSAMIVRKPAHLFLDEIGVAYDEQDTYVVVKHAALFTSTIMSKLLARPNVKLFNAVAAEDLIVKGNRVGGVVTNWALVAQNHHTQSCMDPNVMEAKIVVSSCGHDGPFGATGVKRLKSIGMIDHVPGMKALDMNTAEDAIVRLTREVVPGMIVTGMEVAEIDGAPRMGPTFGAMMISGQKAGQLALKALGLPNAIDGTLVGNLSPELVLAAADSAETVDA
What is the function of this protein?
Involved in biosynthesis of the thiamine precursor thiazole.  Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate.  The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate.  The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme.  May have additional roles in adaptation to various stress conditions and in DNA damage tolerance.  Acts as a positive regulator for the abscisic acid-induced activation of slow type anion channels during stomatal closure by repressing CPK33 kinase activity.
What are the official names of this protein?
Thiamine thiazole synthase, chloroplastic, Thiazole biosynthetic enzyme.
What is the protein family that this protein belongs to?
Belongs to the THI4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast. Mitochondrion. Cell membrane.
Protein: EDNRB_HORSE
Sequence: MQPLPTLCGRVLVALILACGVAGVQGEERRFPPARATPPLLGFEEIMTPPTKTSWPTGSNASVPRLSAPPQMPKAGRTAGAQRRTLPPPPCERTIEIKETFKYINTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIIIDIPINVYKLLAEDWPFGVEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAVGFDMITADYKGSYLRICLLHPTQKTAFMQFYKNAKDWWLFSFYFCLPLAITAFFYTLETCEMLRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKHTLYDQNDPHRCELLSFLLVLEYIGINMASLNSCINPIALYLVSKRFKNCFKWCLCCWCQSFEEKQSLEDKQSCLKFKANDHGYDNFRSSNKYSSS
What is the function of this protein?
Non-specific receptor for endothelin 1, 2, and 3.  Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
What are the official names of this protein?
Endothelin receptor type B, ET-B, ET-BR, Endothelin receptor non-selective type.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Endothelin receptor subfamily. EDNRB sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=internalized after activation by endothelins.
Protein: AFP2_ARATH
Sequence: MGEASRQQRAWNREMTVTTNLSLDIDKYPRDLLRGFMSENGGGRVFHGGETNCDDESTIELNLGLSLGGRFGVDKTPRKLKRSSSVLDTVPFNDSTVAEPENYTVGLERTTSLPAEMEEEWRKRKEMQSLRRMEAKRRRCEKQSFRVGNSDDQTVSFENERWVTASKSGFLQRHLVSSNRQVCGVDSDGGGATGGGSSSSLSELDNKNQQGSSNSCNDERSPKIVAGCSSNSGSQGTERPSVTRANKVNENENEKRVRSEDSVDRKGKGMATSTGLVDMPCVFTKGDGPNGRRVDGILYKYGKGEEVRIMCICHGSFLTPAEFVKHGGGGDVDRPLRHIVVNTSSSTF
What is the function of this protein?
Acts as a negative regulator of abscisic acid (ABA) response during germination through the ubiquitin-mediated proteolysis of ABI5/DPBF1.
What are the official names of this protein?
Ninja-family protein AFP2, ABI five-binding protein 2, ABI5-binding protein 2.
What is the protein family that this protein belongs to?
Belongs to the Ninja family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACCD_STRMK
Sequence: MSWLSKLMPSGIRTDNTPSKKRSVPEGLWEKCSNCGSALYRPELEENLEVCPKCGHHMAIRARARLAALFDADSTTEIGARLGPTDLLKFKDQKKYSERIKIAQKNTGEYDALIAMRGLLKGRALVASSFDFAFMGGSMGSVVGERFALAAETAVEIGAPYVCFSQSGGARMQEGLFSLMQMAKTSAALGKLRETGLPYISVLTHPTTGGVSASFAMLGDINIAEPQALIGFAGPRVIEQTVREKLPEGFQRSEFLLEHGAIDQICDRREMRDRLSDLLAMLGRQPAPEVA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRCA_CHLP8
Sequence: MLYRDLTLRERQVLGIIIQSFVVSATPVGSRTIARNYNLGLSDATIRNVMADLEADGFISQPHTSAGRVPTDKGYRYYVDLLMNVSGIDEQEKQMIDARFSTRSSELKGTSAEVLGAAAKVLGSISRQLGVVLPPRLSNAVFERLDIVQLASTRIMVVIAIQSLFVKTIVMELTAEISRQKIDDVVNILNERLSGLTLEEIRSTIGKRLSDCQSREGLMNSIVGAADTLFDESSILDRLYVSGTENIVDQPEFKQPQKVRNIITMIEDKFGIARLVDNALPSGAYQGRDREVAISIGTENRTDNAIDLTIVSSPYYAGKMVGKVGIMGPKRMDYEHAVRVVNYMAGCLSEALSGNN
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: HDG9_ARATH
Sequence: MDFTRDDNSSDERENDVDANTNNRHEKKGYHRHTNEQIHRLETYFKECPHPDEFQRRLLGEELNLKPKQIKFWFQNKRTQAKSHNEKADNAALRAENIKIRRENESMEDALNNVVCPPCGGRGPGREDQLRHLQKLRAQNAYLKDEYERVSNYLKQYGGHSMHNVEATPYLHGPSNHASTSKNRPALYGTSSNRLPEPSSIFRGPYTRGNMNTTAPPQPRKPLEMQNFQPLSQLEKIAMLEAAEKAVSEVLSLIQMDDTMWKKSSIDDRLVIDPGLYEKYFTKTNTNGRPESSKDVVVVQMDAGNLIDIFLTAEKWARLFPTIVNEAKTIHVLDSVDHRGKTFSRVIYEQLHILSPLVPPREFMILRTCQQIEDNVWMIADVSCHLPNIEFDLSFPICTKRPSGVLIQALPHGFSKVTWIEHVVVNDNRVRPHKLYRDLLYGGFGYGARRWTVTLERTCERLIFSTSVPALPNNDNPGVVQTIRGRNSVMHLGERMLRNFAWMMKMVNKLDFSPQSETNNSGIRIGVRINNEAGQPPGLIVCAGSSLSLPLPPVQVYDFLKNLEVRHQWDVLCHGNPATEAARFVTGSNPRNTVSFLEPSIRDINTKLMILQDSFKDALGGMVAYAPMDLNTACAAISGDIDPTTIPILPSGFMISRDGRPSEGEAEGGSYTLLTVAFQILVSGPSYSPDTNLEVSATTVNTLISSTVQRIKAMLKCE
What is the function of this protein?
Probable transcription factor that binds to the DNA sequence 5'-GCATTAAATGCGCA-3'.
What are the official names of this protein?
Homeobox-leucine zipper protein HDG9, HD-ZIP protein HDG9, Homeodomain GLABRA 2-like protein 9, Homeodomain transcription factor HDG9, Protein HOMEODOMAIN GLABROUS 9.
What is the protein family that this protein belongs to?
Belongs to the HD-ZIP homeobox family. Class IV subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL15_RHOP2
Sequence: MKLSEISDNPGARKKRMRIGRGIGSGKGKTGGRGGKGQTARSGVRIKGFEGGQMPLHRRLPKRGFNNIFRLEFAEINLDRLQDAIDAKTIDAGAVINAESLVAAGVLRRSRDGVRLLGRGELKAKLTIEVHGATKSAIEAVEKAGGSVKILAPKKDEGEAA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: SECA_ALKCK
Sequence: MLGLLRKIVGDPAQKQLKKNEKIVDQVEALADEMKQLSDEQLKNKTTEFKAKLEEGASLNDIVVPALAVAREAAGRVLNEYPYRVQLLGALALHQGNIAEMKTGEGKTLVGTIAVYVQALEGKGVHIVTVNNYLARRDLENYGRIFQFLGLTVGLNENGLTREEKQKAYAADVTYSTNNELGFDYLRDNMVLYKEQMVQRPLHFALIDEVDSILIDEARTPLIISGSVERKTKLYGQANTFVRVLKRDADYTYDEKTKSVQLTDEGVNKAERAFNIDNLYDQKHVQLNHHINQSLKAHVAMHRDADYVVEDGEVVIVDQFTGRLMKGRRYSDGLHQALEAKEGLEVQRESITLASITFQNYFRMYQKLAGMTGTAKTEEEEFRNIYGMDVMVIPTNKPVAREDRPDLIYKTMQGKFNAVVNEIAELHKTGRPVLVGTVNVETSEVVSKMLTRKRIPHHVLNAKNHEREAEIIEKAGHKGAVTIATNMAGRGTDIKLGPGVKELGGLHVLGTERHESRRIDNQLRGRAGRQGDVGSSQFYLSMEDELMRRFGSDNMKAMMEKLGMEDDQPIESSLVSRAVETAQKRVEGNNFDARKQVLQFDDVMREQREIIYRQRMEVLEADNLKTIVENMMKATVERVVQTHCPESLVQEEWDLAAVATYINGQLLSENGISEKELKGKEQEELIELITEKVLAAYHAKEAEVSSEQMREFEKVIMLRTVDRKWMNHIDQMDQLRQGIHLRAYGQNDPLREYRFEGFNMFEAMIAEIEEEVSMYVMKAQVQQNLKREEVAEGKAVRPSANGQEDKKAKRKPVRKAENIGRNDPCICGSGKKYKNCCGANR
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: CISY_RICAE
Sequence: MTDENNNDSEFAELKIRGKIFKLPILKASIGEDVIDISRVSAEADCFTYDPGFMSTASCQSTITYIDGDKGILRHRGYDIKDLAEKSDFLEVAYLLIYGELPSGEQYNNFTKQVAHHSLVNERLHYLFQTFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIAAMSYKYSIGQPFIYPDNSLDFTENFLHMMFATPCTKYTVNPIIKNALNKIFILHADHEQNASTSTVRIAGSSGANPFACISTGIASLWGPAHGGANEAVINMLKEIGSSEYIPKYIAKAKDKNDPFRLMGFGHRVYKNYDPRAAVLKETCKEVLKELGQLDNNPLLQIAIELEAIALKDEYFIERKLYPNVDFYSGIIYKAMGIPSQMFTVLFVIARTVGWMAQWKEMHEDPEQKISRPRQLYTGYVHREYKGIRER
What are the official names of this protein?
Citrate synthase.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.