PharMolix/UniProtQA huggingface dataset:
Protein: ERG27_SCHPO
Sequence: MSFRKYALITGSNSGLGFGIATRLLQFYQPRLQDEPEVFTVILTCRSREKAEDACRRLKEFFPDRKIRLEYVLLDLSNMASVEAAVQDIATRFPKLDFVYLNAGAWDLEGIQWLKAIFSTLINPIQALTHPTFYKETAGRVSNDSLGYIFESNVFGHFYLKNRLAELKVLRSSTKVVLTSSLVAEKKSLDFEDLQCFHGEQPYQSSKRLLDVLHYAELEKGLPFEQYLVHPGLCTTNMYETFLGPILVMCAKLGFYICRLLGSPWHTISPYVAAFAFLWTALHATKEDQSIKWGAAVTRFGHERVLSTPVELILPSEQEKALEYMTKLYQEWKKKLVS
What is the function of this protein?
3-keto-steroid reductase; part of the third module of ergosterol biosynthesis pathway that includes by the late steps of the pathway (By similarity).  Erg27 is a catalytic component of the C-4 demethylation complex that catalyze the reduction of the keto group on the C-3 (By similarity).  The third module or late pathway involves the ergosterol synthesis itself through consecutive reactions that mainly occur in the endoplasmic reticulum (ER) membrane.  Firstly, the squalene synthase erg9 catalyzes the condensation of 2 farnesyl pyrophosphate moieties to form squalene, which is the precursor of all steroids.  Secondly, squalene is converted into lanosterol by the consecutive action of the squalene epoxidase erg1 and the lanosterol synthase erg7.  The lanosterol 14-alpha-demethylase erg11/cyp1 catalyzes C14-demethylation of lanosterol to produce 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol.  In the next steps, a complex process involving various demethylation, reduction and desaturation reactions catalyzed by the C-14 reductase erg24 and the C-4 demethylation complex erg25-erg26-erg27 leads to the production of zymosterol.  Erg28 likely functions in the C-4 demethylation complex reaction by tethering erg26 and Erg27 to the endoplasmic reticulum or to facilitate interaction between these proteins.  Then, the sterol 24-C-methyltransferase erg6 catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol.  The C-8 sterol isomerase erg2 catalyzes the reaction which results in unsaturation at C-7 in the B ring of sterols and thus converts fecosterol to episterol.  The sterol-C5-desaturases erg31 and erg32 then catalyze the introduction of a C-5 double bond in the B ring to produce 5-dehydroepisterol.  The C-22 sterol desaturase erg5 further converts 5-dehydroepisterol into ergosta-5,7,22,24(28)-tetraen-3beta-ol by forming the C-22(23) double bond in the sterol side chain.  Finally, ergosta-5,7,22,24(28)-tetraen-3beta-ol is substrate of the C-24(28) sterol reductase erg4 to produce ergosterol (PubMed:18310029) (Probable).  In the genus Schizosaccharomyces, a second route exists between lanosterol and fecosterol, via the methylation of lanosterol to eburicol by erg6, followed by C14-demethylation by erg11/cyp1 and C4-demethylation by the demethylation complex erg25-erg26-erg27 (PubMed:8586261) (Probable).
What are the official names of this protein?
3-keto-steroid reductase erg27, Ergosterol biosynthetic protein 27.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. ERG27 subfamily.
Protein: MATK_JUNEF
Sequence: MENFQGYLEKYEFCQHQCLYPLLFQEYIYALAYDYDLNTCLFSESVDELISYDNKYSSVLVKRLITRMYQQNYLINSVNHSKFNSFIANNHFFYSHFYSQMISEGFGIILEIPFSLEFLSFSKRKKRLKLQNLRSIHSIFSFLEDKLLXFHXMSDILIPYPIHFEILIQILQYWIQDISFLHLVRFFFFEYLNWNTLITSKNWVSIFLKENQRLFRFLYNSYVSEYEFVFLFLSTKSSYLRFTSFGIFLERIYFYGKIKHFRIVYVTSLQRTLWFFTDSFIHYVRYQGKAILSSRGTFLLMKKWKSYLVCFWQYYFHFWFQPNRILINQFFNYSFYFFGYLLSLKKNHLVVRGQILENSVLIDTMNNQLDTIVPVIXLIRSLSIATFXTXSGHPISKPIWADLSDRDILTRFGRISRNLFHYYSGSSKKWGLYRIKFILRLSCARTLARKHKSTVRTFMQKLGGMFLEEFFTEEEQVLSLVFQKIIHFSLHRSNRERIWYLDIIRINDLVNYFELRS
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MED31_CANAL
Sequence: MSAQTDQPITEQQKKEQEQYTNLINSLPTRWEIELEFVQSLSNIPYVNYLAQNNYFNDENFINYLNYLQYWTQPEYSKFLVYPNCLHILKLLQDENFRKNIINQDFMNSLMNDMVKRWQSNANDQDENKEKEENKEVPEVRINGTN
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 31, Mediator complex subunit 31.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 31 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GHRA_SALTI
Sequence: MEIIFYHPTFNAAWWVNALEKALPHARVREWKVGDNNPADYALVWQPPVEMLAGRRLKAVFVLGAGVDAILSKLNAHPEMLDASIPLFRLEDTGMGLQMQEYAASQVLHWFRRFDDYQALKNQALWKPLPEYTREEFSVGIIGAGVLGAKVAESLQAWGFPLRCWSRSRKSWPGVESYVGREELRAFLNQTRVLINLLPNTAQTVGIINSELLDQLPDGAYVLNLARGVHVQEADLLAALDSGKLKGAMLDVFSQEPLPQESPLWRHPRVAMTPHIAAVTRPAEAIDYISRTITQLEKGEPVTGQVDRARGY
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
What are the official names of this protein?
Glyoxylate/hydroxypyruvate reductase A, 2-ketoacid reductase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRSA1_LISMO
Sequence: MTKLKKVMISVIAATLLLLAGCGSSAVIKTDAGSVTQDELYEAMKTTYGNEVVQQLTFKKILEDKYTVTEKEVNAEYKKYEEQYGDSFESTLSSNNLTKTSFKENLEYNLLVQKATEANMDVSESKLKAYYKTWEPDITVRHILVDDEATAKEIQTKLKNGEKFTDLAKEYSTDTATSTNGGLLDPFGPGEMDETFEKAAYALENKDDVSGIVKSTYGYHLIQLVKKTEKGTYAKEKANVKAAYIKSQLTSENMTAALKKELKAANIDIKDSDLKDAFADYTSTSSTSSTTTSN
What is the function of this protein?
Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.
What are the official names of this protein?
Foldase protein PrsA 1.
What is the protein family that this protein belongs to?
Belongs to the PrsA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: RL10_PELPB
Sequence: MKRDRKEEIVQEVAEKINRSQGIYLTEFQGLSVAKMSELRREFRKVGVEYRVVKNTLIKQALKDLAGADKLAPGLKSTTAVAFGFDDPVAPAKVIRKFSKTNDALKFKMASIDGVVFGPDQLPLLSEMLTKTENIGRAAGLINGVVSSVPMVVNAVMRNLVCALDQIAKQKQ
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: MNMG_PSEU2
Sequence: MVDFPSRFEVIVIGGGHAGTEAALASARMGVKTLLLTHNVETLGQMSCNPAIGGIGKSHLVKEIDALGGAMAMATDKGGIQFRVLNSRKGPAVRATRAQADRVLYKAAIRETLENQPNLWIFQQACDDLIVDQDQVRGVVTQMGMRIFADSVVLTTGTFLGGLIHIGMQNYSGGRAGDPPSIALAQRLRELPLRVGRLKTGTPPRIDGRSVDFSVMTEQPGDTPIPVMSFLGNKEQHPPQVSCWITHTNARTHEIIASNLDRSPMYSGVIEGIGPRYCPSIEDKIHRFADKESHQVFIEPEGLTTHELYPNGISTSLPFDVQLQIVRSIRGMENAHIVRPGYAIEYDYFDPRDLKYSLETKVIGGLFFAGQINGTTGYEEAGAQGLLAGTNAALRAQGRDSWCPRRDEAYIGVLVDDLITLGTQEPYRMFTSRAEYRLILREDNADLRLTEKGRELGLVDDARWAAFCIKRESIELEEQRLKSTWVRPGTEQGDAIAAHFGTPLTHEYNLLNLLTRPEIDYASLISITGQGCTDPQVAEQVEIKTKYAGYIDRQQDEIARLRASEDTRLPEDIDYAAISGLSKEIQSKLGITRPETLGQASRIPGVTPAAISLLMIHLKKRGAGRQLEQSA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YLX3_CAEEL
Sequence: MSFLNINRFHILCFFLWQFGLFYACQLIFPIFYNFHPGLSCEDPGFNFSKPKCKLSKVEICTELTANCSKWHIEPAPFHSMVQDFKMFCGTKAYDSAWIATIQFIGALVGALVYGHLGDHFGRKPVSFVGISIGIIFGVASGFAPSWEVFAVLLFICGTSVACIMIVFYAYILEFIEPEQRVFLRTFFNWGYARLVFTLVCFICGYWRSAAIATSLLALPILPVLLWLPESPKWYATKNRFQEMKEAEKKISWLSGISYVEREDRRTEKIEEKDTKVYTIRDLFSSWPIAYSTIVVGSLWFSTSVSSFGADLNSGNLAGNFYLSQFVQAAAIALSKLSIFLLDLFIPSFNRQRLHQVPQIIMIACYTTIMALMISPDSDCSSQGSRNLAIIIINIIGTSFIELTWDACYLVAAEIFPTRIRTIGIGTCSLLARIGALLAPQMAYLSEIYPPIPYIIVCSIGIISLLISCFFLPDTKGVDLGALDRNPLEESGDNKEEEISEIQIGTN
What are the official names of this protein?
Uncharacterized protein F23F12.3.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS13_SHEFN
Sequence: MARIAGINIPDQKHTVIALTAIFGIGRTRARAICASTSIAEDAKIKELSEAQIDILREEVAKYTVEGDLRREISMNIKRLMDLGCYRGLRHRRSLPLRGQRTKTNARTRKGPRKPIRK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: PUR4_PSESM
Sequence: MLILRGAPALSAFRHSKLLEQLKQKVSAVSGLYAEFAHFADVNDVLTGEEQQVLDRLLKYGPSVPVQEPAGRLFLVLPRFGTISPWSSKASDIARNCGLTKIQRIERGIAFYVEGQFSDADAQAIADSLHDRMTQLVLGDHAQAAGLFSHAEPKPLTAVDILGGGRAALEKANVELGLALAEDEIDYLITSFNGLGRNPHDIELMMFAQANSEHCRHKIFNASWDIDGQSQEKSLFGMIKNTYEMHSEGVLSAYKDNASVIVGSVAGRFFPDPDTRQYGAVQEPVHILMKVETHNHPTAIAPFPGAATGSGGEIRDEGATGRGAKPKAGLTGFTVSNLQIPGFVQPWEVPYGKPERIVTALDIMIEGPLGGAAFNNEFGRPALTGYFRTFEQSITTPHGDEVRGYHKPIMLAGGMGNIREDHVQKAEITVGSKLIVLGGPAMLIGLGGGAASSMATGTSSADLDFASVQRENPEMERRCQEVIDRCWQLGDRNPISFIHDVGAGGLSNAFPELVNDGDRGGRFELRNVPNDEPGMAPLEIWSNESQERYVLAVGVADYERFKAICERERCPFAVVGEATAEPQLTVTDSHFGNSPVDMPLEVLLGKAPRMHRSVAREAEIGDDFDPSTLDIEESVQRVLRHPAVASKSFLITIGDRSITGLVARDQMVGPWQVPVADCAVTATSFDVNTGEAMAMGERTPLALLDAPASGRMAIGETLTNIAASRIEKLSDIKLSANWMSAAGHPGEDARLYDTVKAVGMELCPELGITIPVGKDSMSMKTRWSDEGTEKSVTSPLSLIVTGFAPVVDIRKTLTPELRMDKGITDLILIDLGRGQNRMGASILAQTHGKLGRVAPDVDDAEDLKAFFAVIQGLNSDGHILSYHDRSDGGLLVSTLEMAFAGHCGLNLHLDGLADNVSELSAILFNEELGAVIQVRQDATPLVLAQFSAAGLEDCVAVIGQPINNDEVSISFLGEPVFSGQRRLLQRQWAETSYQIQRLRDNAECADQEFDALLEEDNPGLTVKLGFDVNEDIAAPYIKTGVRPQVAVLREQGVNGQVEMAAAFDRAGFNAIDVHMSDILAGRVDLNDFKGMVACGGFSYGDVLGAGEGWAKSALFNSRARDAFQGFFERSDSFTLGVCNGCQMLSNLHELIPGSEFWPHFVRNRSEQFEARVAMVQVQESASIFLQGMAGSRMPIAIAHGEGHAEFRNDDALLEADVSGTVALRFVDNHGKVTESYPANPNGSPRGIGGMTTLDGRVTIMMPHPERVFRAVQNSWRPEDWNEDAAWMRMFRNARAWVN
What is the function of this protein?
Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase, FGAM synthase, FGAMS, Formylglycinamide ribonucleotide amidotransferase, FGAR amidotransferase, FGAR-AT.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F136A_DANRE
Sequence: MAEAQQARVQNAVEEMVQNLEKEHIRKMQGRMFRCSAECCEHPGNSMNQVHQCIERCHTPLAKAQGLVTSELEQFQDRLSRCTMHCSDKAKDLFDSGAKEPAVRALMDGCVGSCVDEHLNLLPSMTRRLKDSLNSIPQ
What are the official names of this protein?
Protein FAM136A.
What is the protein family that this protein belongs to?
Belongs to the FAM136 family.
Protein: TRPB_SHEWM
Sequence: MTKLDPYFGEYGGMYVPQILMPALKQLETAFVEAQEDEAFKTEFNDLLKNYAGRPTALTLTRNLSPNPLVKIYLKREDLLHGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVATALACALLDLKCKVYMGAKDVERQSPNVFRMKLMGAEVIPVTSGSSTLKDACNEAMRDWSGSYDKAHYLLGTAAGPHPFPTIVREFQRMIGAETKKQILEREGRLPDAVIACVGGGSNAIGMFADFIDEESVKLIGVEPAGLGIDTPMHGAPLKHGKTGIFFGMKAPLMQDREGQIEESYSISAGLDFPSVGPQHAHLAATGRATYESATDDEALEAFQLLARSEGIIPALESAHALAYAVKMAKAATQETILVVNLSGRGDKDIFTVADILEERERSQTGQQKEESGND
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: OBG_FRAAA
Sequence: MPTFVDRVVLHAAAGDGGHGCASIHREKFKPLGGPDGGDGGRGGDVRLVVDPSVTTLLDFHFHPHQRASRGRPGQGSNRSGADGEDLILPVPDGTVVLTGDGEQLIDLVGAGSAFVLARGGRGGRGNAALASARRKAPGFAELGEPGELLDAVLELKTVADVALVGFPSAGKSSLVSVLSAAKPKIADYPFTTLVPNLGVARAGDHPPYTVADVPGLIPGASEGRGLGLEFLRHIERCSLIVHVLDCATLEPGRDPLTDLDVIEAELAAYSADLSDRPRLVVLNKIDVPDAADLADLVTADLRARGLDVFAVSSATRRGVHALSLALAERVAALRAAAPSRAATRVVLRPRAVNEPDFTVTSHGDGFLISGAKPQRWVRQTDFTNDEAIGFLADRLARLGVEKELARLGATAGVEVTIGDVTFEWEPTLSGGGLGGAGLAGDGTAVDLLGADEPGAGAQAAAAGERSPGVPTAAPPRPAGRAVAATASLGPRGSDDRLSGSVRLTRAERMARARRARLSDADADADIDASGADARTGGAVDADA
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2203_AQUAE
Sequence: MKGTFLVLRRVRGGDVDLVATLYGTAGKVSLFLREGYLNEKKLFGVFEPFNLVKIDYYQSSGLIIPRDVLEVKRFSYFAKDVKRYFLMSYISQTVLRHINFYDEELFSLILRFFLKETKNPEASYFKFFLNLLKTLGYEPLFLRERVRGRYAFLDLEKGSLSSSGVKVRSSLLNLLKKIHQLEEYERIKIKRKDFEEGREILEKFLSFHLNR
What are the official names of this protein?
Uncharacterized protein aq_2203.
Protein: RS11_SHEON
Sequence: MAKVPSRSPRKRVRKQVADGMAHIHASFNNTIVTITDRQGNALSWATSGGSGFRGSRKSTPFAAQVAAERAGAAAQDYGLKNLEVFVKGPGPGRESAIRALNAVGYKITNITDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: HXC5_NOTVI
Sequence: ETDGKRSRTSYTRYQTLELEKEFHFNRYLTRRRRIEIANNLCLNERQIKIWFQNRRMKWKKDSKLKIKDSL
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-C5, Homeobox protein Hbox-3.4, NvHbox-3.4.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPB2_DROME
Sequence: MMYDNEEELYEEENAEEISHELWQEACWIVINAYFDEKGLVRQQLDSFDEFIQMSVQRIVEDSPAIELQAEAQHTSGEVETPPRFSLKFEQIYLSKPTHWEKDGSPSPMMPNEARLRNLTYSAPLYVDITKTKNVEGLDPVETQHQKTFIGKIPIMLRSTYCLLSQLTDRDLTELNECPLDPGGYFIINGSEKVLIAQEKMATNTVYVFSMKDGKYAFKTEIRSCLEHSSRPTSTLWVNMMARGSQNIKKSAIGQRIIAILPYIKQEIPIMIVFRALGFVADRDILEHIIYDFDDPEMMEMVKPSLDEAFVVQEQNVALNFIGARGARPGVTKDKRIKYAKEILQKEMLPHVGVSDFCETKKAYFLGYMVHRLLLASLGRRELDDRDHYGNKRLDLAGPLLAFLFRGLFKNLMKEVRMYTQKFIDRGKDFNLELAIKTNIITDGLRYSLATGNWGDQKKAHQARAGVSQVLNRLTFASTLSHLRRVNSPIGRDGKLAKPRQLHNTLWGMLCPAETPEGAAVGLVKNLALMAYISVGSQPSPILEFLEEWSMENLEEIAPSAIADATKIFVNGCWVGIHRDPEQLMATLRKLRRQMDIIVSEVSMIRDIRDREIRIYTDAGRICRPLLIVENGSLLLKKTHVEMLKERDYNNYSWQVLVASGVVEYIDTLEEETVMIAMSPYDLKQDKDYAYCTTYTHCEIHPAMILGVCASIIPFPDHNQSPRNTYQSAMGKQAMGVYITNFHVRMDTLAHVLYYPMKPLVTTRSMEYLRFRELPAGINSIVAILCYTGYNQEDSVILNASAVERGFFRSVFYRSYKDSENKRVGDQEENFEKPHRGTCQGMRNAHYDKLDDDGIIAPGIRVSGDDVVIGKTITLPENDDELDSNTKRFSKRDASTFLRNSETGIVDQVMLTLNSEGYKFCKIRVRSVRIPQIGDKFASRHGQKGTCGIQYRQEDMAFTCEGLAPDIIINPHAIPSRMTIGHLIECLQGKLGSNKGEIGDATPFNDAVNVQKISTFLQEYGYHLRGNEVMYNGHTGRKINAQVFLGPTYYQRLKHMVDDKIHSRARGPVQILVRQPMEGRARDGGLRFGEMERDCQISHGAAQFLRERLFEVSDPYRVHICNFCGLIAIANLRNNTFECKGCKNKTQISQVRLPYAAKLLFQELMSMNIAPRLMVT
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Second largest component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs.  Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit.  Pol II is the central component of the basal RNA polymerase II transcription machinery.  It is composed of mobile elements that move relative to each other.  RPB2 is part of the core element with the central large cleft, the clamp element that moves to open and close the cleft and the jaws that are thought to grab the incoming DNA template (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase II subunit RPB2, RNA polymerase II subunit 2, RNA polymerase II subunit B2, DNA-directed RNA polymerase II 140 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RGPA1_HUMAN
Sequence: MFSKKPHGDVKKSTQKVLDTKKDALTRLKHLRIVIENAESIDLKQFFDQHFSHIYYVFFENFVTIEASLKQKGHKSQREELDAILFIFEKILQLLPERIHQRWQFHSIGLILKKLLHTGNSLKIRREGVRLFLLWLQALQNNCSKEQLWMFSCLIPGFSAPQSEHGPRTLDNLINPPLNLQETQVTIEEITPLVPPQSGDKGQEDLTSYFLEALLKYIVIQVKSLEWKNKENQERGFSFLFSHFKKYYLPYIFPNICKENSLYHPILDIPQMRPKPHYVVIKKDAETNEAIYCTKEPFIKARVIVIRWLVSFWLEPKPHTGPHIPGMEGEVLPKNIQRAAASLVSREESKNDNADKTDRTTEPEQSHSNTSTLTEREPSSSSLCSIDEEHLTDIEIVRRVFSSKRSNVNFVTEIFRQAFLLPICEAAAMRKVVKVYQEWIQQEEKPLFMQEPEEIVITSSDLPCIENVTDHDISMEEGEKREEENGTNTADHVRNSSWAKNGSYQGALHNASEEATEQNIRAGTQAVLQVFIINSSNIFLLEPANEIKNLLDEHTDMCKRILNIYRYMVVQVSMDKKTWEQMLLVLLRVTESVLKMPSQAFLQFQGKKNMTLAGRLAGPLFQTLIVAWIKANLNVYISRELWDDLLSVLSSLTYWEELATEWSLTMETLTKVLARNLYSLDLSDLPLDKLSEQKQKKHKGKGVGHEFQKVSVDKSFSRGWSRDQPGQAPMRQRSATTTGSPGTEKARSIVRQKTVDIDDAQILPRSTRVRHFSQSEETGNEVFGALNEEQPLPRSSSTSDILEPFTVERAKVNKEDMSQKLPPLNSDIGGSSANVPDLMDEFIAERLRSGNASTMTRRGSSPGSLEIPKDLPDILNKQNQMRPIDDPGVPSEWTSPASAGSSDLISSDSHSDSFSAFQYDGRKFDNFGFGTDTGVTSSADVDSGSGHHQSAEEQEVASLTTLHIDSETSSLNQQAFSAEVATITGSESASPVHSPLGSRSQTPSPSTLNIDHMEQKDLQLDEKLHHSVLQTPDDLEISEFPSECCSVMAGGTLTGWHADVATVMWRRMLGILGDVNSIMDPEIHAQVFDYLCELWQNLAKIRDNLGISTDNLTSPSPPVLIPPLRILTPWLFKATMLTDKYKQGKLHAYKLICNTMKRRQDVSPNRDFLTHFYNIMHCGLLHIDQDIVNTIIKHCSPQFFSLGLPGATMLIMDFIVAAGRVASSAFLNAPRVEAQVLLGSLVCFPNLYCELPSLHPNIPDVAVSQFTDVKELIIKTVLSSARDEPSGPARCVALCSLGIWICEELVHESHHPQIKEALNVICVSLKFTNKTVAHVACNMLHMLVHYVPRLQIYQPDSPLKIIQILIATITHLLPSTEASSYEMDKRLVVSLLLCLLDWIMALPLKTLLQPFHATGAESDKTEKSVLNCIYKVLHGCVYGAQCFSNPRYFPMSLSDLASVDYDPFMHLESLKEPEPLHSPDSERSSKLQPVTEVKTQMQHGLISIAARTVITHLVNHLGHYPMSGGPAMLTSQVCENHDNHYSESTELSPELFESPNIQFFVLNNTTLVSCIQIRSEENMPGGGLSAGLASANSNVRIIVRDLSGKYSWDSAILYGPPPVSGLSEPTSFMLSLSHQEKPEEPPTSNECLEDITVKDGLSLQFKRFRETVPTWDTIRDEEDVLDELLQYLGVTSPECLQRTGISLNIPAPQPVCISEKQENDVINAILKQHTEEKEFVEKHFNDLNMKAVEQDEPIPQKPQSAFYYCRLLLSILGMNSWDKRRSFHLLKKNEKLLRELRNLDSRQCRETHKIAVFYVAEGQEDKHSILTNTGGSQAYEDFVAGLGWEVNLTNHCGFMGGLQKNKSTGLTTPYFATSTVEVIFHVSTRMPSDSDDSLTKKLRHLGNDEVHIVWSEHTRDYRRGIIPTEFGDVLIVIYPMKNHMFSIQIMKKPEVPFFGPLFDGAIVNGKVLPIMVRATAINASRALKSLIPLYQNFYEERARYLQTIVQHHLEPTTFEDFAAQVFSPAPYHHLPSDADH
What is the function of this protein?
Catalytic subunit of the heterodimeric RalGAP1 complex which acts as a GTPase activator for the Ras-like small GTPases RALA and RALB.
What are the official names of this protein?
Ral GTPase-activating protein subunit alpha-1, GAP-related-interacting partner to E12, GRIPE, GTPase-activating Rap/Ran-GAP domain-like 1, Tuberin-like protein 1, p240.
Protein: LV1B_BUTOS
Sequence: MANVQVIFVAYIAVIAFSMVYGDDYKPFGEHNSYYGCKKQTDEFCNKICKLHLAKKGGFCHQPAPFVELCKCLDIDYDNTYFLKAMEKQCPKLKGNVN
What is the function of this protein?
The monomer edited version, similar to alpha-toxins, may modulate voltage-gated sodium channels (Nav) and may block voltage-gated potassium channels (Kv).
What are the official names of this protein?
Lipolysis-activating peptide 1-beta chain, BoiLVP1-beta, LVP1-beta, Putative beta-like toxin Tx457.
What is the protein family that this protein belongs to?
Belongs to the long (3 C-C) scorpion toxin superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MRAY_NOSP7
Sequence: MDAKLSPEQGLNISGIALASLLAVGLGTTAFFLDSMANRLPWQSMSLTLPLLLCAMGSGVVGFWVIPLLQALKTGQIIREDGPQAHLKKAGTPTMGGIFFIPVGVIIACILSNFATDVLAVSALTTSYGFIGWLDDWQILRRKSNKGISPRTKLALQVGFAAVFCLWLMFNQPSNITNIALPWVSFTLPLGFLFWPLAGFVLVAESNATNLTDGIDGLAAGTVAIALLALGALIAPTAPGLMVFCAALSGGCLGFLAHNRNPARVFMGDTGSLALGGALAAVALLTNTLVALFILSGIFFVETLSVMAQVSYYKATKGPDGKGKRLFKMAPLHHHLELTGWSELQVVGVFYVIAAILAAICLA
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DEXT_STRSL
Sequence: MTVNLTLQHASEIIGQDNVDLTLAAGASAKVSNLTVASEWLTNNTGYLVTISVNDKSGNVLSSKRAGLSVEDDWTVFPRYGIVAGSPTDQNSILVKNLEAYRKELELMKSMNINSYFFYDAYNEATDPFPEGVDSFVQKWNTWSHTQVDTKAVKELVDQVHKSGAVAMLYNMISADSNPKNPALPLAALAYNFYDSFGKKGEPMTYTIGDNPTQVYYDPANPDWQKYIAGVMKSAMDRMGFDGWQGDTIGDNRVTDYEHRNSTDEADSHMMSDSYASFINAMKDLIGEKYYITINDVNGGNDDKLAKARQDVVYNELWTNGGSVIPGRMQVAYGDLKARIDMVRNKTGKSLIVGAYMEEPGIDYTVPGGKATNGAGKDALAGKPLQADATLLVDATVAAAGGYHMSIAALANANAALNVLQSAYYPTQYLSVAKDTIRKLYNYQQFITAYENLLRGEGVTNSTQAVSTKNASGEILSKDALGVTGDQVWTFAKSGKGFSTVQMINMMGINAGWHNEEGYADNKTPDAQENLTVRLSLAGKTAQEAAKIADQVYVTSPDDWATSSMKKAQASLETDENGQPVLVISVPKLTLWNMLYIKEDTTATPVEPVTNQAGKKVDNTVTSEASSETAKSENTTVNKGSEAPTDTKPSVEAPKLDETTKPAPSVDELVNSAAVPVAIAVSETAHDKKDDNSVSNTDQGTVASDSITTPASEAASTAASTVSSEVSESVTVSSEPSETENSSEASTSESATPTTTAISESHAVVEPVASLTESESQASTSLVSETTSTIVSVAPSEVSESTSEEVILMDYQKTSIVGIDSL
What are the official names of this protein?
Dextranase, Alpha-1,6-glucan-6-glucanohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 66 family.
Protein: AROK_BACC3
Sequence: MKSIYITGYMGAGKTTIGKALSKELHMDVVDTDQKIEEKQEKAILDIFAEEGEMAFREYESEMLRSLPVRNAIITTGGGIIEREENRKWMKENGIVVYLYCDPHVIAERLREDTTRPLFQKKDIDAFVTKFESRQAYYEEAHIHIDTTNKSVKQIMNELKEKINE
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLIP_AQUAE
Sequence: MRKALTILILSAGFVFSQIPPIELKVGEGNLVDSIRLLIFLTILSLVPSILIMFTSFTRLVVVLSLLRQAIGTPQAPPNQVIIALSLFLTFFIMKPTIDKINSEALQPYIREEISDEEFFKRVEFYAKDFMLKHTRKETLEAFLSIAKIPKDSVKEPHEIPLRVVIPAFMVSELKTAFEIVFLLYIPFLIVDLVVASILISMGIIMIPPQLISLPFKIMLFVLANGWELVVLSLVRSYQ
What is the function of this protein?
Plays a role in the flagellum-specific transport system.
What are the official names of this protein?
Flagellar biosynthetic protein FliP.
What is the protein family that this protein belongs to?
Belongs to the FliP/MopC/SpaP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Bacterial flagellum basal body.