PharMolix/UniProtQA huggingface dataset:
Protein: MLTF_CHRSD
Sequence: MFDALLRYMRPVATAFVALLALLIPDNRTSHEPDAALSAILSRDFIQVFTRNTPTTYYEGRHGPTGFEYDLVRRFAESLDVSLSLNSVGNIGDVLSAVRDGRADLGAATLSLDPAEPGILYSRPIMSMQPMVIYHRGIPAPTTPEDLLGLDIAALRGSGTGRALRDLQKSLPELTWQETDELEVTDLIEMVEKGEFDAAVVYAHQFKLNRLFFPDVENGFMLGAPQSLVWAFPKDSGVALLQAANRLIDRLHASGQLDELIARYFGHDDYLEYVGARLFIRHAQARLPRYEAAFKEAARDTGFDWKLLAALGYQESHWKPRATSPTGVRGLMMLTNDTAAEVGVTNRLDPEQSIEGGATYLLHVKGRLQEEITEPDRTWMALAAYNVGLGHLYDAQKITEMQGGDPYKWADVRKALPLLQKRKWYSQVRHGYARGGEPVIYVRNIRRYYEILNYVDRSRRQFHHLGERDDTFPQTPFNTVPPVL
What is the function of this protein?
Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product.  Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus.  Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase F, Murein lyase F.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane.
Protein: ISPG_BACC7
Sequence: MNEMTHRTKTRPVKVGNLTIGGNNELIIQSMTTTKTHDVEATVAEIKRLEEAGCQVVRVAVPDERAANAIADIKKQINIPLVADIHFDYRLALKAIEGGIDKVRINPGNIGRRHKVEAVVNAAKERGIPIRIGVNAGSLERHILEKYGYPTADGMVESALHHIKILEDLDFHDIIVSMKASDVNLAIEAYEKAARAFDYPLHLGITESGTLFAGTVKSAAGLGAILSKGIGNTLRISLSADPVEEVKVARELLKSFGLASNAATLISCPTCGRIEIDLISIANEVEEYISTLQVPIKVAVLGCAVNGPGEAREADIGIAGARGEGLLFRKGQVVRKVPEEIMVEELKKEIDVIAAEMAAEREKEKETQEQ
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: PRIM_VZVO
Sequence: MDKSSKPTIRLLFATKGCAISHSLLLLTGQISTEPLYVVSYTWTPDLDDVFVKNGREEITQVIPTKRPREVTENDEENQIMHLFCSRDVNVIFYLIGGFSTGDVRSRVWPIFFCCFKTQTDFKALYKALWYGAPLNPHIISDTLCISETFDIHSEVIQTLMVTTHHLNRKGLSDNGLCITEATLCKLVKKSVGRQELTSLYAHYERQVLAAYRRLYWGYGCSPFWYIVRFGPSEKTLVLATRYYLLQTDTSYNTLETPLYDLQAIKDLFLTYQVPALPNCSGYNISDLLSFDKLSMFCCSSTYTRGLTAKNALSYILQRIHTDTTEIHAVSEYITNDRKGLKVPDREFVDYIYLAHFECFNRKQIADHLQAVTYSDFVNKPVLLKSSNLGKRATANFFNHVRSRLNMRDYIKKNVICDVTELGPEIGHKYTITKTYTLSLTYAAKPSKFIGVCDLATTLTRRVENIEKQFSPYGWSSTIPSNPPGFDELSNFEDSVVSAEALRAANFANDTPNQSGRTGFDTSPGITKLLLFFSAATGIATHDVSILSYKTPLEALIGHSEVTGPMPVYRVALPQGAQAFAVIANDTWSSITNRYTLPHEARLIAEDLKQINPCNFVAASLRDMQLTLLLSTSVKNVSKISSNIPKDQLYINRNELFNTNLIITNLILDVDFHIRKPIPLGILHAGMRAFRHGILTAMQLLFPKAVVNPNKDPCYFYKTACPEPTVEVLDDDNLLDITSHSDIDFYIENGELYTCVEENYTEDVWFFDTQTTSEVHTHADVSNNENLHETLPCNCKEKIGFRVCVPIPNPYALVGSSTLKGFAQILQQAVLLEREFVEYIGPYLRDFSFIDTGVYSHGHSLRLPFFSKVTTTGTAVGQLLPFYVVPEQCIDILAFVTSHRNPANFHFHSRPQSNVPVQFILHNLGGEYAEFFERKVARNKQIFSPPQISLTKALKERGVTCLDAFTLEAFVDSTILESIVEHIAVHFPGRDREYTLTSSKCIAIKRDWVLFQLICGTKGFTCLRYPHRGGRTAPRTFVSLRVDHHNRLCISLAQQCFATKCDSNRMHTIFTLEVPNYPNLTSS
What is the function of this protein?
Essential component of the helicase/primase complex.  Unwinds the DNA at the replication forks and generates single-stranded DNA for both leading and lagging strand synthesis.  The primase initiates primer synthesis and thereby produces large amount of short RNA primers on the lagging strand that the polymerase elongates using dNTPs.
What are the official names of this protein?
DNA primase.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae DNA primase family.
What are the subcellular locations of this protein?
Host nucleus. Note=Requires the presence of the primase associated factor to properly localize in the host cell nucleus.
Protein: Y4490_PSEAE
Sequence: MRRLTAFGLALLLLASGVARGEPAVTLDPQQSQVFRAWFVRIAQEQLRQGPSPRWHQQDCAGLVRFAANEALKVHDGKWLRANGLSNRYLPPELALSPEQRRLAQNWQQGGGQVGPYVNAIKLVQFNSRLVGRDLNQARPGDLMFYDQGDDQHLMIWMGRSIAYHTGSSTPTDNGMRSVSLQQLMTWKDTRWIPDESNPNFIGIYRLAFLSQ
What are the official names of this protein?
Uncharacterized protein PA4490.
What is the protein family that this protein belongs to?
To E.coli YfaT and T.maritima TM0986.
Protein: IRS4_ASPFU
Sequence: MDDKSRGTTNAKHLATDTDHPPDDGSAGLPEPGSVKSKTGLFTARSTQKALDGERDEFATFRTRPPQQAAIAMQKPPVPVNKPVTLGRPNSTPELRQTESQGSDDRAEPGYPMSKPVRNMTAGADTVENLLQDNRELPVRNPPIPHRNPAMHPDTSPRPPDIASVSGTKPRPTPPPPRKGGAKPVPKSPSRNEPKIHGEKQSYIPLSNSDVDLTGADEARPTLPPRPDPSRVTHIPPSDHRILLEAHEHSKRHLTPSSPLLDRSLQNNGSSPDLIDYSPGLDEEAMSDAIVASSLASRKAFSAKKVPPPPPPQRQLRTHPLLRPNTPSSDSPRSSSPAPSLRHTLRPATKVGEEELDHHKHRKHIIRRHPHKHHEGDRKRWQSEVTEKERKRYEGVWAANKGLLIPISNSKERSSLEEVSCEGYPPSASEMVLNIAVREIWARSRLPSSILEKIWNLVDRQKIGLLTREEFVVGMWLIDQQLKGHKLPVEVPGSVWDSVRGVPGIRIPKVPSR
What is the function of this protein?
Positive regulator of phosphatidylinositol 4,5-bisphosphate turnover and negatively regulates signaling through the cell integrity pathway.  Involved in rDNA silencing (By similarity).
What are the official names of this protein?
Increased rDNA silencing protein 4.
What is the protein family that this protein belongs to?
Belongs to the IRS4 family.
Protein: TRM56_METJA
Sequence: MVVEVLRLGHRGDRDKRISTHVALTARALGADKIIFTTEDEHVENSVKKVVESWGGNFEFVVEKHWRKYIREFKKRGIVVHLTMYGANINEIMPEIREISRDKDILVIVGAEKVPKEVYELADYNVSVGNQPHSEVAALAIFLDRLFEGKTLYRDFEDAKIKIVPSKDGKVVIREKQNK
What is the function of this protein?
Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.
What are the official names of this protein?
tRNA (cytidine(56)-2'-O)-methyltransferase, tRNA ribose 2'-O-methyltransferase aTrm56.
What is the protein family that this protein belongs to?
Belongs to the aTrm56 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_MYCPU
Sequence: MLQPKRTKHRKMFRIRHDKKDAFKGNKVSFGEYGLQATTSAWITARQIESARIAATRRMGREGQVIIRIFPHLSKTSKPIGVRMGSGKGSPEKWYSVVKRQTMMFEVSGIKPEVAKDALRLAGHKLPVKWRIVEASPKEEVI
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: LYRA_STAHJ
Sequence: MKTNRISGFQWALTIFVFFVVTMALSLILRDFQASVGIKRFVFDITDLAPFIAAIVCIIAFKDKRTQLAGLKFSVDIRVIERILLALILPLVIFMIGMFSFNTFADSFILLQATDLSVSVPTIIIGHILMAFFAEFGFRSYLQNIVENKVNTFFASIIVGLIYSIWAANTTYGMEYAGYHFLYTFMFSIIIGELIRATKGRTIYIALVFHASMSFAQVFLFSEETGDLFSMKVIALSTTLVGIVFIILSLIIRFIVYKTTNRSLDEVEPNNYLDHMNDDDTTTSNETKSEDHEHNDKKDSFTESQLNEDHVELKSQSENQTDSSNEKLKENTSYKEDRRSSVVDDAKDEIDQMKDTSSHKTEK
What are the official names of this protein?
Lysostaphin resistance protein A.
What is the protein family that this protein belongs to?
Belongs to the LyrA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y117_ATV
Sequence: MGVWSVVLYLLNTLIVPFRDERAKFEIERVSAEEAKKIIQMHNSQFVSAIGHSASANALSLLLGVAVPVNRTEVFFNVGDEAIAMALKKRLAEGQVLRTVQELEAVGFDLYYIKRVQ
What are the official names of this protein?
Uncharacterized protein ORF117.
Protein: ENVZ_SALTS
Sequence: MRRMRFSPRSSFARTLLLIVTLLFVSLVTTYLVVLNFAILPSLQQFNKVLAYEVRMLMTDKLQLEDGTQLVVPPAFRREIYRELGISLYTNEAAEEAGLRWAQHYEFLSHQMAQQLGGPTEVRVEVNKSSPVVWLKTWLSPNIWVRVPLTEIHQGDFSPLFRYTLAIMLLAIGGAWLFIRIQNRPLVDLEHAALQVGKGIIPPPLREYGASEVRSVTRAFNHMAAGVKQLADDRTLLMAGVSHDLRTPLTRIRLATEMMGEEDGYLAESINKDIEECNAIIEQFIDYLRTGQEMPMEMADLNSVLGEVIAAESGYEREINTALQAGSIQVKMHPLSIKRAVANMVVNAARYGNGWIKVSSGTESHRAWFQVEDDGPGIKPEQRKHLFQPFVRGDSARSTSGTGLGLAIVQRIIDNHNGMLEIGTSERGGLSIRAWLPVPVARVQGTTKEA
What is the function of this protein?
Member of the two-component regulatory system EnvZ/OmpR involved in osmoregulation (particularly of genes ompF and ompC) as well as other genes (PubMed:2543631).  EnvZ functions as a membrane-associated protein kinase that phosphorylates OmpR in response to environmental signals; at low osmolarity OmpR activates ompF transcription, while at high osmolarity it represses ompF and activates ompC transcription (Probable).
What are the official names of this protein?
Sensor histidine kinase EnvZ, Osmolarity sensor protein EnvZ.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NIT2_DANRE
Sequence: MSKFRLAVVQLHVSKIKADNLGRAQTLVKEAAGQGAKVVVLPECFNSPYGTGFFKEYAEKIPGESTQVLSETAKKCGIYLVGGSIPEEDGGKLYNTCSVFGPDGTLLVTHRKIHLFDIDVPGKIRFQESETLSPGKSLSMFETPYCKVGVGICYDIRFAELAQIYAKKGCQLLVYPGAFNMTTGPAHWELLQRGRAVDNQVYVATASPARDETASYVAWGHSSVINPWGEVISKAGSEESVVYADIDLQYLADVRQQIPITKQRRNDLYSVNSVQEG
What is the function of this protein?
Has omega-amidase activity.  The role of omega-amidase is to remove potentially toxic intermediates by converting 2-oxoglutaramate and 2-oxosuccinamate to biologically useful 2-oxoglutarate and oxaloacetate, respectively.
What are the official names of this protein?
Omega-amidase NIT2, Nitrilase homolog 2.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CA198_BOVIN
Sequence: MASMAAAIAASRTAVMSANRPLDDRERKRFTYFSSLSPMARKIMQDKEKIREKYGPEWARLPPAQQDEIIDRCLVGPSASAPGDPEELARFPGLRGPTGQKVVRFGDEDITWQDEHSAPFSWETRSQMEFSISSLSIQEPSCSTAGEPRPPSKAPQGSQALRAPQGGKSSSLDALGPAWKEEEASFWKINAERSRGEGPEAEFQSLTPSQIKSMEKGEKVLPGCYRQEPAPRAREAKAEKPSPLRQEQRAAPSVSTECERPQPAQACASPPSEAGPSGPMGKPVSPEVMEAVEDMEDALFLEPVPVQVSSSNVILKTGFDFLDNW
What are the official names of this protein?
Uncharacterized protein C1orf198 homolog.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPA_BACMK
Sequence: MTKQTEYKRKPEWLKIKLNTNENYTGLKKMMRSKNLHTVCEEAKCPNIHECWAVRKTATFMILGAVCTRACRFCAVKTGLPTELDLQEPERVADSVVQMGLKHVVITAVARDDLKDGGAAVFAETVRAVRRENPFTSIEVLPSDMGGVEENLKMLMDAKPDILNHNIETVRRLSNRVRARAKYDRSLEFLRRAKEMQPDIPTKSSIMLGLGETREDLIEAMDDLRANNVDILTLGQYLQPSKKHLPVIKYYPPAEFAELKEIALSKGFSHCEAGPLVRSSYHADEQVRSAKEKTAEAK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LYSM3_CHICK
Sequence: MAGRGTGCSLQLPAGTQPPGGGHLYPGESEGPEEESEVFELRPRGREKVRRSTSRDRLDGIILLTKDIQEGDTLNAIALQYCCSVADIKRVNNLINDQDFFALRSIKIPVKKFSVLTETHVSPKGRTVLRPAHYSPEVQEASPDKFTANETAGNFLKEVDRDIEEIVKCNDTKRENLNEVVSALAAQQVCFETDGRSKKCKDPYYGADWGIGWWTAVVIMLIIGIVTPVFYLLYYEVLVKADVSHHSTMESAHSFVTAASHQKQIEHGRSPANSINVDSQGDIRPYNRKPQANVIHRHIT
What is the function of this protein?
Essential for Golgi structural integrity.
What are the official names of this protein?
LysM and putative peptidoglycan-binding domain-containing protein 3.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Golgi apparatus.
Protein: RECF_SACD2
Sequence: MPHLSNLKVQQFRNLGLVDITPSPTLNLVYGENGSGKTSLLEAISVLAHCRSFRTHKYRRLIQDTTTAFTVFATVEGSDAFKVGVQREWSGKSTAKLDGLSAKSSAQLATNLPVQIIDAHTFALLEGGSKARRKFFDWLVFHVKHEFKTAWANYVKCVKQRNSLLRHDKIAYSDLRPWDEQIAGLAATIDECRVECITPLIQAFKALMGECKFADNVDLTLAYQPGWKEGELSFPKQLEQAFARDRKLGYTILGPHKSDLKITANGSPAVEVLSRGQQKAVINALHIAEAQVYKTQIGRTPVFLLDDMPSELDANHIAILSGWLSNLGAQVFVTGVDANKLASVWPLQKNEAIKMFHVKQGEVTVSQ
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSSR_STAAN
Sequence: MVQCLVVDDDPRILNYIASHLQTEHIDAYTQPSGEAALKLLEKQRVDIAVVDIMMDGMDGFQLCNTLKNDYDIPVIMLTARDALSDKERAFISGTDDYVTKPFEVKELIFRIRAVLRRYNINSNSEMTIGNLTLNQSYLELQVSNKTMTLPNKEFQLLFMLAARPKQIFTREQIIEKIWGYDYEGDERTVDVHIKRLRQRLKKLNATLTIETVRGQGYKVENHV
What is the function of this protein?
Member of the two-component regulatory system HssS/HssR involved in intracellular heme homeostasis and tempering of staphylococcal virulence.  Phosphorylated HssR binds to a direct repeat sequence within hrtAB promoter and activates the expression of hrtAB, an efflux pump, in response to extracellular heme, hemin, hemoglobin or blood (By similarity).
What are the official names of this protein?
Heme response regulator HssR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPTD_IDILO
Sequence: MLQRFITSLMLLPFPGSALAALQNQDAPQHMTCTVAQPTESMIGAVQLQKTEAGTIGVESRSAEILANEKAYFTGNVIIQRNGQWLSTSKATIDQQRGEILASDGITFNDGYLSVTGDSLSLDLNDDQAKLYNSDYRLQNHNARGHAELLSLSRQEVLLQDSSFTTCPGETPAWQLRAERIEINETSDFGEAWHARFELFDVPVLYLPYFNFPLSDARKTGLLYPTFDSSSNSGFEVEVPYYFNIAPNMDATIAPVYMSERGTMMKGEYRYLFEQNAGQFNLEYLGNDDTRIANKKRYLWHVQHSAQINQDLSFYLDATEISDDNYLNDFGSDFAGRADTHLYRVAQLDYDNENWTAQLRTEDYELIGDYRSPYRTLPQLSIDYNTGDFTGFSASLYNELTYFQNQDQTREYATRAHIEPSIQYRFEKPAFDTEAELSYLYTRYWQESPDANITEEVTRTLPRARVRARLHLERAIELGDSQYRQTLSPQIQYLYVPYENQQNIGIYDTSLLQDDYHGLFRSRRFSGLDRIAEANQITYGVSSSLFTQNEREVLRASIGQIYNINDSRTQLFASDEETTTSSNSEWVADINWAVDENWSIRSSIQYDTELNTTRKSQTAVEFRKDESNLIQVSHRTATNILNNDIEQVGTQAVWSANSRWQVASNVFYDLTHDRLNDAMVGIQYSSCCWALRVSAYRRINRDLEPAFSATQINGETQFDNGISIQFIISGLASDSSGLINMLEKSTYGYRRPFYLSN
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: RL10_LATSS
Sequence: MSETIIAKKAQIVDTVVEKFNNAVSIVVMDYRGLTVEQVTELRKQLREAGVQMEVVKNTYLRRAADKAGYEGLDDTFTGPTAVAFSNEDVVAPAKIIANFSKSADALEIKGGMIEGKVATLDEINALATLPSRDGLLSMLLSVLQAPVRNVAYAVKAVADSKDEPAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: MOC_ORYSJ
Sequence: MLRSLHSSSSSDTDNNSGGCKNNGGGGGEAAAAVEGGGDQRAVAAAAPSTRDLLLACADLLQRGDLPAARRAAEIVLAAAASPRGDAADRLAYHFARALALRVDAKAGHGHVVVGGGAARPASSGAYLAFNQIAPFLRFAHLTANQAILEAVDGARRVHILDLDAVHGVQWPPLLQAIAERADPALGPPEVRVTGAGADRDTLLRTGNRLRAFARSIHLPFHFTPLLLSCATTAPHHVAGTSTGAAAAASTAAAATGLEFHPDETLAVNCVMFLHNLAGHDELAAFLKWVKAMSPAVVTIAEREAGGGGGGGDHIDDLPRRVGVAMDHYSAVFEALEATVPPGSRERLAVEQEVLGREIEAAVGPSGGRWWRGIERWGGAARAAGFAARPLSAFAVSQARLLLRLHYPSEGYLVQEARGACFLGWQTRPLLSVSAWQPSSS
What is the function of this protein?
Putative transcription regulator that controls rice tillering by initiating axillary buds and promoting their outgrowth.  Rice tiller is a specialized grain-bearing branch that is formed on the unelongated basal internode and grows independently of the mother stem (culm) by means of its own adventitious roots.
What are the official names of this protein?
Protein MONOCULM 1.
What is the protein family that this protein belongs to?
Belongs to the GRAS family.
Protein: OBG_NOSP7
Sequence: MQFIDQAKIEVEAGKGGDGIVAFRREKYVPTGGPSGGNGGRGGSVFFVADENLQTLLDFRYNHRFQAEKGTRGGPNNCTGAGGKDLIIEVPCGTTIYDAETGELLGDLTEPQQTLLIAQGGKGGLGNQHFLSNRNRAPEYALPGLPGEIKQLRLELKLLAEVGIIGLPNAGKSTLISSLSAARPKIADYPFTTLIPNLGVVRKPTGDGTVFADIPGLIAGASHGAGLGHDFLRHIERTRVLLHLIDATSDDVIRDYNTIKEELQAYGQGLAERPQILALNKIDAVDRETVDLEALATQLNHLSYAPVFIISAVTRTGLEPMLQEIWGILDQMKVPEEVEALR
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPTE_ECO55
Sequence: MRYLATLLLSLAVLITAGCGWHLRDTTQVPSTMKVMILDSGDPNGPLSRAVRNQLRLNGVELLDKETTRKDVPSLRLGKVSIAKDTASVFRNGQTAEYQMIMTVNATVLIPGRDIYPISAKVFRSFFDNPQMALAKDNEQDMIVKEMYDRAAEQLIRKLPSIRAADIRSDEEQTSTTTDTPATPARVSTTLGN
What is the function of this protein?
Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.  Required for the proper assembly of LptD.  Binds LPS and may serve as the LPS recognition site at the outer membrane.
What are the official names of this protein?
LPS-assembly lipoprotein LptE.
What is the protein family that this protein belongs to?
Belongs to the LptE lipoprotein family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: SSB2_STRA3
Sequence: MYNKVIMIGRLTAKPEMVKTPTDKSVTRATVAVNRRFKGSNGEREADFINVVMWGRLAETLASYGTKGSLISVDGELRTRKYEKDGQTHYITEVLASSFQLLESRSQRAMRENNISGDLSDLVLEEEELPF
What is the function of this protein?
Plays an important role in DNA replication, recombination and repair.  Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
What are the official names of this protein?
Single-stranded DNA-binding protein 2, SSB 2.
Protein: TSAD_PROM1
Sequence: MSIILSLETSCDESAAALVSNEKGKIDLLANEIASQIDEHANWGGVVPEIASRRHLENLPFLIEEVFAKSTLQIKDIDAVAATVTPGLAGSLLVGSITARTLANLHQIPFLGIHHLEGHLSSIYLSENHPKPPFLVLLVSGGHTELIKVDVKHKYQRLGRSHDDAAGEAFDKVARLLGLSYPGGPAIQKIAKSGDPKKFLFPKGRVSKPEGGFYPYDFSFSGLKTAVFRQIEKIRSENKKLPIEDIAASFEYIVAEVLVERSFKCALDQGLNSLVLVGGVAANVRLREMMLAKASKNSIDITLAPMEFCTDNAAMIGAAALLRLSSEGFKSSMELGVSARWPLEKSDSLYDPIPPF
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_SOLM1
Sequence: MAKKPALSPQEFRSEALATALTTIERKHGQGAVMRLEDSAHVKIPAIPTGSIGLDLALGIGGIPKGRITEIYGPESSGKTTLALHIIAESQKLGGTAAFIDAEHALDVNYARRLGVNTPEMLISQPDFGEQALDIADLLVRSGAVDVVVIDSVAALIPQAELEGEMGETQVGGQARLMSHAMRKLTGTIHKSQTSVIFINQIRMKIGMTGYGSPETTTGGNALKFYASVRLDIRRIQTLKDKEETYGSRCRVKVVKNKVAPPFREALFDILYGTGVSREGELIDMGVEAGIVDKSGAWFAFGSERLGQGRDNVRAFLQEHTDIRDQIEGKLREHLGFAEYVPPPSPEVMEEEDGM
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCPA_BACC0
Sequence: MQYNFKVEAFEGPLDLLLHLIHRYEIDIYNIPVAEITEQYLSYVHTMKELQLDVASEYLVMAATLLQIKSKMLLPKHEEDVLDNGDDFIDDPRQELMERLIEYKKYKQVATELKEREQERAQLYTRPPIDFTSLQQEEETNLPLDVTLYDMLAAFQKLMRRKKAKKPVTTRITRQEIPIEQRMTDILKQLEIQGGRQSFYDLFVDDEREIMVVTFLAVLELMKNQQIIIEQEHNFDEIFVSSYTKSA
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein A.
What is the protein family that this protein belongs to?
Belongs to the ScpA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: SSUB_BACAH
Sequence: MTVLINEVSKYFSKQTGTVQVLENINFQLEKGDFVTVIGPSGCGKSTLLKIVAGLDNDFEGEIIIDGERITKPSKKQGFIFQEHRLFPWLTVEENIAADLSLKDKYVKDKVKEWVEIVRLDGFEKSYPKEISGGMSQRVAIARALLRDPSVLLLDEPFGALDAFTRSHLQEVLLNIWEQKKTTMIFVTHDIDEAIYLSNRIVIMSAKPGKIHKVIENNLPYPRSKTSESFQEIRKKVLQQFEHGGLIQTSI
What is the function of this protein?
Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Aliphatic sulfonates import ATP-binding protein SsuB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3.A.1.17.2) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: NUD10_HUMAN
Sequence: MKCKPNQTRTYDPEGFKKRAACLCFRSEREDEVLLVSSSRYPDRWIVPGGGMEPEEEPGGAAVREVYEEAGVKGKLGRLLGVFEQNQDPKHRTYVYVLTVTELLEDWEDSVSIGRKREWFKVEDAIKVLQCHKPVHAEYLEKLKLGGSPTNGNSMAPSSPDSDP
What is the function of this protein?
Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction.  Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates.  The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A.  Also able to hydrolyze 5-phosphoribose 1-diphosphate.
What are the official names of this protein?
Diphosphoinositol polyphosphate phosphohydrolase 3-alpha, DIPP-3-alpha, DIPP3-alpha, hDIPP3alpha, Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 3-alpha, Diadenosine hexaphosphate hydrolase (AMP-forming), Nucleoside diphosphate-linked moiety X motif 10, Nudix motif 10, hAps2.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. DIPP subfamily.
What are the subcellular locations of this protein?
Cytoplasm.