PharMolix/UniProtQA huggingface dataset:
Protein: Y2787_BRUAB
Sequence: MKEVSLRGISKTFGQLTVLDRIDLEIHSGEFLVLVGPSGCGKSTLLRMVAGLEPISGGDLVIGGERANELPPQKRNIAMVFQSYALFPHMTARENIGFGPRIRGEKAAETAAKVDHAASILNLHSYLDRYPRQLSGGQRQRVAMGRAIVREPSVFLFDEPLSNLDAQLRVQMRTEIKALHQRLKSTVIYVTHDQIEAMTMADRIVVMNQGKIQQIGAPLDLYDRPANKFVAGFIGSPSMSFIPGTVADGFFCTGEGEKIAVSAAAKGARAAEAGIRPENFVIAREGAGLTLVVEVIEPTGPETHIYGRIAGEPVRAVFRERIQLAPGEQVPVTAGSEHIHLFDKESGLPL
What is the function of this protein?
Probably part of an ABC transporter complex.  Probably responsible for energy coupling to the transport system (Probable).
What are the official names of this protein?
Putative ATP-binding protein BruAb2_0487.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: IF5A_SACS2
Sequence: MSITYTTVGELKVGSYVVIDGEPCRVVEVTKAKTGKHGSAKANVVAIGVFSGAKKTLMAPVDQQVEVPIIEKHIGQIIADMGNKIQVMDLESYETFEIEKPTEDELASKIKPNAELEYWEIMGRRKIVRVK
What is the function of this protein?
Functions by promoting the formation of the first peptide bond.
What are the official names of this protein?
Translation initiation factor 5A, Hypusine-containing protein, eIF-5A.
What is the protein family that this protein belongs to?
Belongs to the eIF-5A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INO1_PHAVU
Sequence: MFIESFKVESPNVKYTENEIHSVYDYETTEVVHEKTVNGTYQWIVKPKTVKYDFKTDIRVPKLGVMLVGLGGNNGSTLTAGVIANKEGISWATKDKVQQANYFGSLTQASSIRVGSFNGEEIYAPFKSLLPMVNPDDVVFGGWDISDMNLADAMARARVLDIDLQKQLRPYMENIVPLPGIFDPDFIAANQGSRANHVIKGTKKEQVDHIIKDMREFKEKNKVDKVVVLWTANTERYSNEVVGMNDTMEDLMESVDRDEAEISPSTLYAIACVLEGIPFINGSPQHTFVPGLIDMAIRNNVLIGGDDFKSGQTKMKSVLGDFLVGAGIKPTSIVSYNHLGNNDGMNLSAPQTFRSKEISKSNVVDDMVASNGILFEPGEHPDHVVVIKYVPYVADSKRAMDEYTSEIFMGGKNTIVMHNTCEDSLLAAPIILDLVLLAELSTRIQFKSEGEGKFHSFHPVATILSYLTKAPLVPPGTPVINALSKQRAMLENIMRACVGLAPENNMIMEFK
What is the function of this protein?
Key enzyme in myo-inositol biosynthesis pathway that catalyzes the conversion of glucose 6-phosphate to 1-myo-inositol 1-phosphate in a NAD-dependent manner.
What are the official names of this protein?
Inositol-3-phosphate synthase, MIP synthase, Myo-inositol 1-phosphate synthase, IPS, MI-1-P synthase.
What is the protein family that this protein belongs to?
Belongs to the myo-inositol 1-phosphate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_STRGG
Sequence: MRHYEVMVILDPDLEERAVSPLIENFLSVVREGDGKVEKVDTWGRRRLAYEIKKKPEGIYSVIDLQAEPAVVKELDRQMNLNESVLRTKVLRPEVH
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: KUP_ECO55
Sequence: MSTDNKQSLPAITLAAIGVVYGDIGTSPLYTLRECLSGQFGFGVERDAVFGFLSLIFWLLIFVVSIKYLTFVMRADNAGEGGILTLMSLAGRNTSARTTSMLVIMGLIGGSFFYGEVVITPAISVMSAIEGLEIVAPQLDTWIVPLSIIVLTLLFMIQKHGTAMVGKLFAPIMLTWFLILAGLGLRSIIANPEVLHALNPMWAVHFFLEYKTVSFIALGAVVLSITGVEALYADMGHFGKFPIRLAWFTVVLPSLTLNYFGQGALLLKNPEAIKNPFFLLAPDWALIPLLIIAALATVIASQAVISGVFSLTRQAVRLGYLSPMRIIHTSEMESGQIYIPFVNWMLYVAVVIVIVSFEHSSNLAAAYGIAVTGTMVLTSILSTTVARQNWHWNKYFVALILIAFLCVDIPLFTANLDKLLSGGWLPLSLGTVMFIVMTTWKSERFRLLRRMHEHGNSLEAMIASLEKSPPVRVPGTAVYMSRAINVIPFALMHNLKHNKVLHERVILLTLRTEDAPYVHNVRRVQIEQLSPTFWRVVASYGWRETPNVEEVFHRCGLEGLSCRMMETSFFMSHESLILGKRPWYLRLRGKLYLLLQRNALRAPDQFEIPPNRVIELGTQVEI
What is the function of this protein?
Responsible for the low-affinity transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Low affinity potassium transport system protein Kup, Kup system potassium uptake protein.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GPH_ECO57
Sequence: MSKFEDIRGVAFDLDGTLVDSAPGLAAAVDMALYALELPVAGEERVITWIGNGADVLMERALTWARQERATLRKTMGKPPVDDDIPAEEQVRILRKLFDRYYGEVAEEGTFLFPHVADTLGALQAKGLPLGLVTNKPTPFVAPLLEALDIAKYFSVVIGGDDVQNKKPHPDPLLLVAERMGIAPQQMLFVGDSRNDIQAAKAAGCPSVGLTYGYNYGEAIDLSQPDVIYQSINDLLPALGLPHSENQESKND
What is the function of this protein?
Specifically catalyzes the dephosphorylation of 2-phosphoglycolate.  Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.
What are the official names of this protein?
Phosphoglycolate phosphatase, PGP, PGPase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
Protein: SYH_PHOPR
Sequence: MAKQIQAIRGMNDCLPTQSALWQKVEGTIKQVVSAYGYNEIRMPIVESTHLFKRAIGEVTDVVEKEMYTFEDRNGDSLTLRPEGTAGCVRAGIQNGLLYNQEQRLWYIGPMFRYERPQKGRYRQFHQVGVEVFGLNGPDVDAELIMMTARLWRELGINQHVRLELNSIGSLDARATYREALIAFLEQHLEVLDEDCKRRMHTNPLRVLDTKNPAVQEILVDAPKLSEYLDDDSKAHFAGLCELLDAAGIEYQVNERLVRGLDYYNRTVFEWITESLGAQGTVCGGGRYDGLVEQLGGKATPAVGFAMGVERLVLLMETLELADVRRSVDAYVVTVGEGTMMAGMKLAEKLRENVPGLRVMNHFGGGNFKKQFKRADNVGAAIALVLGENEIADNTVVVKDLRGGEQTTMAQDEVTAKLAELI
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_POLSJ
Sequence: MTEAKKSLKRTLIGKVVSDKRAKTVTVLVERRVKHELYGKIVSLSSKYHAHDEKGEYHTGDVIEITESRPISKTKNWVVTRLVEKAAAV
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: Y2576_MYCTU
Sequence: MPAGVGNASGSVLDMTSVRTVPSAVALVTFAGAALSGVIPAIARADPVGHQVTYTVTTTSDLMANIRYMSADPPSMAAFNADSSKYMITLHTPIAGGQPLVYTATLANPSQWAIVTASGGLRVNPEFHCEIVVDGQVVVSQDGGSGVQCSTRPW
What are the official names of this protein?
Uncharacterized protein Rv2576c.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: HLDE_VIBA3
Sequence: MKPILPDYSQSGVLVVGDVMLDRYWYGPTGRISPEAPVPVVKVENNEERPGGAANVAMNIASLGGHAHIVGLTGKDEPAEVLKNTLGALKVKCDFVELDDYPTITKLRVMSRGQQLIRLDFEDKFENTDPELVLSRMEQALPNVRSVILSDYAKGALEHVQSFIQKARAANVPVFIDPKGADFERYRGATLLTPNMAEFELVAGKVKSEDEMIEKGLALIEEFDFEALLVTRSEHGMTLLRKGVEPFHLPTQAKEVYDVTGAGDTVISVLAASVAAGKPLDEACALANAAAGVVVGKLGTSTLSTIELAEAIHGSQDTDYGVISEAALVEAVKRARAKGEKVVMTNGCFDILHAGHVSYMNHAAELGDRLIVAVNTDESVKRLKGPGRPVNPTDRRMAVLAGLGAVDWVVPFSEDTPQRLISEVLPSILVKGGDYKPEEIAGGAEVIAAGGEVKVLNFEDGCSTTEIIKAIKGGRG
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: MURD_NITOC
Sequence: MLNEPLQPQVAATSVILGLGKTGLSSARFLASRGFSIAVMDSRKSPPGLAALQEQNPDAVLRLGGFDAALIAEAEQLVVSPGVALSEPAILAARARGIPVVGDIELFASYVKAPVIGITGSNGKSTVTSLLEAMARQAGRQVLAGGNLGTPALELLEKPVPDLYILELSSFQLETTYTLDAVAACVLNISPDHMDRYPDLDAYCQAKARIYRGTGTMVINADDFRVASLVQPHRPCLRFTLGMPAVDEYGLQERAGETWLVRGHERLLSARRLPLAGRHNLANALAALALGEAVGLPRAAMLSALQAFSGLPHRCEWLAEVNGVRWYNDSKGTNVGATVAAIEGIPCQGKLILIAGGVGKGADFSPLSKPLIQRARAVVLMGQDASRLEAVLASGPPLYRVNSMDEAVVKANVLAQSGDCVLLSPACASFDMYADFEARGQAFRQAVREILSC
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_ESCF3
Sequence: MSKKIQSVRGMNDYLPVETAVWQRVERIIKSVVESYGYSEIRTPILEQTPLFKRAIGEVTDVVEKEMYTFNDRERDAKEVVSLTLRPEGTAGCVRAGIEHGLLYNQEQRLWYMGPMFRHERPQKGRYRQFHQIGLEVFGLQGPDIDAELIMLTARWWRELGISEHVTLELNSIGSLEARANYRDALVAFLEQHKEKLDEDCKRRMYTNPLRVLDSKNPEVQALLNDAPALGDYLDEESREHFAGLCKLLESAGIAYTVNQRLVRGLDYYNRTVFEWVTNSLGSQGTVCAGGRYDGLVEQLGGRATSAVGFAMGLERLVLLVQAVNPEFKADPVVDIYLVASGADTQPAAMALAERLRDELPGVKLMTNHGGGNFKKQFGRADKWGARIAVVLGESEVANGTAVVKDLRSGEQTAVAQDSVAAHLRTLLG
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARFB_METTM
Sequence: MVELNLDAGNVISGDVHRVGILALGSHLENHGPALPIDTDAKIASYVALEASLRTGAKFLGVIYGATEFPYVKHGIHIERDELLEGDLKPVLRKARKRLNIDAAVIVNGHGGNQLEDCVEDLMDELDMEIIWNNRIVEIEGPHAGSGEVSAGIILGIADLTRLGECRPELYPEIGMIGLREAREANKGIDRAARICEKEGINPDPVLGQRILDDAIESVISDVRELLEMLP
What is the function of this protein?
Catalyzes the hydrolysis of the formamide of 2-amino-5-formylamino-6-ribosylamino-4(3H)-pyrimidinone 5'-monophosphate (FAPy) to form 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (APy).
What are the official names of this protein?
2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5'-monophosphate deformylase, FAPy deformylase, Formamide hydrolase.
What is the protein family that this protein belongs to?
Belongs to the creatininase superfamily. FAPy deformylase family.
Protein: RSMA_MYCSJ
Sequence: MTIRLLGRTEIRRLAKDIDFRPRKSFGQNFVHDANTVRRIVSASGVHRHDHVLEVGPGLGSLTLALLDRGAHVTAVEIDPLLAQQLPTTIADHSHSEINRLTVLNQDILTLMPSDLENQPTALVANLPYNVAVPALLHLLAEFPTIRSVMVMVQAEVAERLAADPGGKDYGVPSAKVRFYGNVRRYGMVSPTVFWPIPRVYSGLVRIDRYETSPWPTDADFRAQVFDLIDIAFAQRRKTSRNAFAEWAGSGNESARRLLAASIDPSRRGETLAIADFVRLLQRSGEAEEQVRVQ
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_MYCGI
Sequence: MPKAKTHSGASKRFRKTGTGKIVRQKANRRHLLEHKATKRTRRLDGRTVVAPNDVKRVTKMLNG
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: DGTL1_NEOSM
Sequence: MLSSYSSFPERSKGRLFLEKEDPQRDCYQRDRDRLIHSSAFRRLMYKTQVFSHCGDDHYRTRLTHSLEVAQIARSIARLLGLNEDLTETIALAHDIGHPPFAHIGEEALQEVAAEHYRFEHNAQVLRILGEFEHQYMDFDGLNLTWETIEGLAKHNGPIQEPHQIIEEYNGLLDLELNKQPSLEAQIVSLADDIAYSSHDIDDGLLSGVITYQDLRHLPIIGENILKFEKTFPEASKSQVMYKARRRMIRFLIYDVVDVARENIKRYLLKTVDDIRELGFPAANFSEKVGKEMKEIKAFLYNNLYFYYSIRKSRVKLKRIVKELFEVFFHDPQCLPKDYYERFRIADSMNKKAQLVCDFIANLTDSSAIREHRQFFSTCVLERDY
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 2 subfamily.
Protein: BABA2_MESAU
Sequence: MSPEIALNRISPMLSPFISSVVRNGKVGLDATNCLRITDLKSGCTSLTPGPNCDRFKLHIPYAGESLKWDIIFNAQYPELPPDFIFGEDAEFLPDPSALHNLASWNPSDPECLLLVVKELVQQYHQFQCSRLRESSRLMFEYQTLLEEPQYGENMEIYAGKKNNWTGEFSARFLLKLPVDFSNIPTYLLKDVNEDPGEDVALLSVSFEDTEATQVYPKLYLSPRIEHALGGSSALHIPAFPGGGCLIDYVPQVCHLLTNKVQYVIQGYHKRREYIAAFLSHFGTGVVEYDAEGFTKLTLLLMWKDFCFLVHIDLPLFFPRDQPTLTFQSVYHFTNSGQLYSQAQKNYPYSPRWDGNEMAKRAKAYFKTFVPQFQEAAFANGKL
What is the function of this protein?
Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs).  The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX.  In the BRCA1-A complex, it acts as an adapter that bridges the interaction between BABAM1/NBA1 and the rest of the complex, thereby being required for the complex integrity and modulating the E3 ubiquitin ligase activity of the BRCA1-BARD1 heterodimer.  Component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin in various substrates.  Within the BRISC complex, acts as an adapter that bridges the interaction between BABAM1/NBA1 and the rest of the complex, thereby being required for the complex integrity.  The BRISC complex is required for normal mitotic spindle assembly and microtubule attachment to kinetochores via its role in deubiquitinating NUMA1.  The BRISC complex plays a role in interferon signaling via its role in the deubiquitination of the interferon receptor IFNAR1; deubiquitination increases IFNAR1 activity by enhancing its stability and cell surface expression.  Down-regulates the response to bacterial lipopolysaccharide (LPS) via its role in IFNAR1 deubiquitination.  May play a role in homeostasis or cellular differentiation in cells of neural, epithelial and germline origins.  May also act as a death receptor-associated anti-apoptotic protein, which inhibits the mitochondrial apoptotic pathway.  May regulate TNF-alpha signaling through its interactions with TNFRSF1A; however these effects may be indirect.
What are the official names of this protein?
BRISC and BRCA1-A complex member 2, BRCA1-A complex subunit BRE, BRCA1/BRCA2-containing complex subunit 45, Brain and reproductive organ-expressed protein.
What is the protein family that this protein belongs to?
Belongs to the BABAM2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes at sites of DNA damage at double-strand breaks (DSBs).
Protein: NPCB_RHOOP
Sequence: MLEDPMKQNVLQPLDKAEFRNVVGHFASGVTIVTAAHDGVPYGATISAVTSLCDTPPMVLVCLNQKLGTHAAIRKARHFTINILGEDQASLAHTFATPGADKFADVAVHHRQHGPRLAEALAYLTCRVVDDLEGGTHRIFVAEVVEAQAGTGNPLSYYRGRFGHFVPYRNAMWRTTQADNAVSPH
What is the function of this protein?
Involved in the degradation of para-nitrophenol (4-NP).  Catalyzes both the initial hydroxylation of 4-NP to produce 4-nitrocatechol (4-NCA) and the subsequent oxidative release of the nitro group from 4-NCA to produce 2-hydroxy-1,4-benzoquinone.  It can also use 4-nitroresorcinol as substrate with a rate of nitrite release similar to that observed with the two physiological substrates, 4-PN and 4-NCA.
What are the official names of this protein?
4-nitrophenol 4-monooxygenase/4-nitrocatechol 2-monooxygenase, reductase component, 4-NP/4-NCA monooxygenase, PNP monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the non-flavoprotein flavin reductase family.
Protein: RL7_UREP2
Sequence: MSKLTIEQFIAAIKEMSMLELNDLVKAIETEFGVSAAAPVAAAAAPVAAEAPTEVTIKLVEAGTNKVGVIKLIREITGLGLMEAKTAAETAGSVIKEDVKTEEANEIKKKFDELGAKVQLV
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: FABH_ASCSU
Sequence: MRCLVALILTVLIVTPEVEAKTLPDKFLGTFKLERDENFDEYLKARGYGWIMRQVIKLAGVTKKFRNAASGKPDRYDMENLTTKKDTHHKDWALGEEFQDEALDSTQHKITFDLKDPNTLTETHIKVDDPTDVETYEYRRDGDYLVMKMSWKGVSTSRYYKKQ
What is the function of this protein?
May play a role in sequestering potentially toxic fatty acids and their peroxidation products, or it may be involved in the maintenance of the impermeable lipid layer of the eggshell.
What are the official names of this protein?
Fatty acid-binding protein homolog, AS-P18.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Protein: KCP1_PINMG
Sequence: MYTLFILSLLCVLVTFSECKYPTGPIYPHKPIYPIRPVRPDPCPAVCLILCHKGNIHDKNGCPICRCRPDECALPLKVGPCRARFPRYYFNFMRKRCEFFFWGGCLPNKNNFETIYDCQETCGYAERRYPYPYIKRTY
What are the official names of this protein?
BPTI/Kunitz domain-containing protein 1, Prism serine protease inhibitor 1, PSPI1.
What are the subcellular locations of this protein?
Secreted.
Protein: KEFC_SALA4
Sequence: MDSHTLLQALIYLGSAALIVPIAVRLGLGSVLGYLIAGCIIGPWGLRLVTDAESILHFAEIGVVLMLFVIGLELDPQRLWKLRASVFGGGALQMVVCGGLIGLFCMFLGLRWQVAELIGMTLALSSTAIAMQAMNERNLTVSQVGRSAFAVLLFQDIAAIPLVAMIPLLAASGASTTLGAFALSALKVAGALALVVLLGRYVTRPALRFVARSGLREVFSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLFFIGVGMSIDFGTLVENPLRILLLLAGFLAIKIVMLWLVARPLGVPAKQRRWFAVLLGQGSEFAFVVFGAAQMADVLEPEWAKALTLAVALSMAATPIFLVLLTRMEKTATGEAREADEIDEEQPRVIVAGFGRFGQIAGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQTNLQLSELVKTHFPHLQIIARARDVDHYIRLRQAGVAMPERETFEGALKSGRQALEALGLGRYEARERADLFRHFNTRMVEEMAKGENDPLSRAAAYKRTSAMLSEIITEDREHLSLIQRHGWQGTAEGKHSGEVADEPEVKPSI
What is the function of this protein?
Pore-forming subunit of a potassium efflux system that confers protection against electrophiles.  Catalyzes K(+)/H(+) antiport.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system protein KefC, K(+)/H(+) antiporter.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CUM1_CONCL
Sequence: MTTLGMTMLVLLLLLPLATCLGDGERSPWDSLLRALRSDPQACEPTISGGEMICRDEVCASTGCNCGYNIAKAHCYCACP
What are the official names of this protein?
Conotoxin Cl10.1.
What are the subcellular locations of this protein?
Secreted.
Protein: YBAR_BACSU
Sequence: MNNSFTLKQQWFGNIRKDILAGILVALALIPEAIGFSIIAGVDPMVGLYASFCIAIIISIFGGRPGMISAATGSMAVVMVSLVADHGLQYLFAATILTGIIQVILGISKIARLMKFIPRSVMIGFVNALAILIFSAQLPQFEGASWSMYAMLAGSLVIIYVLPRFTTAVPSPLVAIIVMTIIAVTFHVDVRTVGDMGNISSSLPHFLIPDVPFTFETLQIIFPYSIALAFVGLLESLLTAQIIDEMTDTDSDKNKESRGQGIANIVTGFFGGMAGCAMIGQSVINTKAGGRGRLSAFVAGAFLMFLIAVLSHVVVKIPMAALVAVMVMVSVGTFDWSSLKGLKKAPLTDSIVMVVTVVTVVVTDDLSKGVFVGVLLSAVFFVAKISKLKIVSHAEDQKLRTYQVKGQIFFASVTDLTNAFIYQEDIERVVIDLTEAHVWDDSGAAALDKIVAKFKEQGIEAELKGLNKASKSLMKQMA
What are the official names of this protein?
Putative sulfate transporter YbaR.
What is the protein family that this protein belongs to?
Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MENA_SYNY3
Sequence: MTESSPLAPSTAPATRKLWLAAIKPPMYTVAVVPITVGSAVAYGLTGQWHGDVFTIFLLSAIAIIAWINLSNDVFDSDTGIDVRKAHSVVNLTGNRNLVFLISNFFLLAGVLGLMSMSWRAQDWTVLELIGVAIFLGYTYQGPPFRLGYLGLGELICLITFGPLAIAAAYYSQSQSFSWNLLTPSVFVGISTAIILFCSHFHQVEDDLAAGKKSPIVRLGTKLGSQVLTLSVVSLYLITAIGVLCHQAPWQTLLIIASLPWAVQLIRHVGQYHDQPEQVSNCKFIAVNLHFFSGMLMAAGYGWAGLG
What is the function of this protein?
Involved in the synthesis of phylloquinone (vitamin K1).  Catalyzes the transfer of a prenyl chain to 2-carboxy-1,4-naphthoquinone.
What are the official names of this protein?
2-carboxy-1,4-naphthoquinone phytyltransferase, 1,4-dihydroxy-2-naphthoate phytyltransferase, DHNA phytyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MenA family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NGFV1_PSETE
Sequence: MSMLCYTLIIAFLIGIWAAPKSEDNVPLGSPATSDLSDTSCAQTHEGLKTSRNTDQRHPAPKKAEDQELGSAANIIVDPKLFQKRRFQSPRVLFSTQPPPLSRDEQSVEFLDNEDTLNRNIRAKRETHPVHNRGEYSVCDSISVWVANKTKAMDIKGKPVTVMVDVNLNNHVYKQYFFETKCRNPNPVPSGCRGIDSRHWNSYCTTTHTFVKALTMEGNRASWRFIRIDTACVCVISRKTENF
What is the function of this protein?
Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems.  It stimulates division and differentiation of sympathetic and embryonic sensory neurons as well as basal forebrain cholinergic neurons in the brain.  Its relevance in the snake venom is not clear.  However, it has been shown to inhibit metalloproteinase-dependent proteolysis of platelet glycoprotein Ib alpha, suggesting a metalloproteinase inhibition to prevent metalloprotease autodigestion and/or protection against prey proteases (By similarity).  Binds a lipid between the two protein chains in the homodimer.  The lipid-bound form promotes histamine relase from mouse mast cells, contrary to the lipid-free form (By similarity).
What are the official names of this protein?
Venom nerve growth factor 1, v-NGF-1, vNGF-1.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: TPIS_PRIM3
Sequence: MRKPIIAGNWKMNKVLSEATSFVEEVKGAVPSPESVDSVVCAPALFLDRLVEATKGTDLKIGAQNMHFEENGAFTGEVSPVALADLGVNYVILGHSERREMFAETDETVNQKTIAAFKHGLTPIVCCGETNEEYEQDQTKTVVANQVQKALAGLTDEQVKQTVIAYEPIWAIGTGKSSTAEGANEVCAYIRSVVAEQFSQDVADAVRIQYGGSVKPANIKEYMSQSDIDGALVGGASLEADSFLQLLEAGK
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_BRUAB
Sequence: MAVPKRKTSPSRRGMRRSADALKAPTYVEDKNSGELRRPHHIDLKSGMYRGRQVLEPKE
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: FIBB_TAPTE
Sequence: LSDYDEEEDERAKATLDAR
What is the function of this protein?
Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix.  Fibrin has a major function in hemostasis as one of the primary components of blood clots.  In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization.  Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood.  However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo.  Enhances expression of SELP in activated platelets.  Maternal fibrinogen is essential for successful pregnancy.  Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage.  May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.
What are the official names of this protein?
Fibrinogen beta chain.
What are the subcellular locations of this protein?
Secreted.
Protein: NUOA1_PSEA7
Sequence: MPNPAELAAHHWGFAAFLLGVVGLLAFMLGVSALLGSKAFGRSKNEPFESGIVPTGGARLRLSAKFYLVAMLFVIFDVEALFLFAWSVSVRESGWAGLIEATIFIAILLAGLVYLWRIGALDWAPESRRKRQAKLKQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A 1, NADH dehydrogenase I subunit A 1, NDH-1 subunit A 1, NUO1 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.