PharMolix/UniProtQA huggingface dataset:
Protein: TM2D3_HUMAN
Sequence: MAGGVLPLRGLRALCRVLLFLSQFCILSGGEQSQALAQSIKDPGPTRTFTVVPRAAESTEIPPYVMKCPSNGLCSRLPADCIDCTTNFSCTYGKPVTFDCAVKPSVTCVDQDFKSQKNFIINMTCRFCWQLPETDYECTNSTSCMTVSCPRQRYPANCTVRDHVHCLGNRTFPKMLYCNWTGGYKWSTALALSITLGGFGADRFYLGQWREGLGKLFSFGGLGIWTLIDVLLIGVGYVGPADGSLYI
What are the official names of this protein?
TM2 domain-containing protein 3, Beta-amyloid-binding protein-like protein 2, BBP-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the TM2 family.
Protein: MANEA_MOUSE
Sequence: MAKFRRRTCILLSLFILFIFSLMMGLKMLWPNAASFGPPFGLDLLPELHPLNAHSGNKADFQRSDRINMETNTKALKGAGMTVLPAKASEVNLEELPPLNYFLHAFYYSWYGNPQFDGKYIHWNHPVLEHWDPRIAKNYPQGQHSPPDDIGSSFYPELGSYSSRDPSVIETHMKQMRSASIGVLALSWYPPDSRDDNGEATDHLVPTILDKAHKYNLKVTFHIEPYSNRDDQNMHQNIKYIIDKYGNHPAFYRYKTRTGHSLPMFYVYDSYITKPTIWANLLTPSGSQSVRSSPYDGLFIALLVEEKHKNDILQSGFDGIYTYFATNGFTYGSSHQNWNNLKSFCEKNNLMFIPSVGPGYIDTSIRPWNTQNTRNRVNGKYYEVGLSAALQTHPSLISITSFNEWHEGTQIEKAVPKRTANTIYLDYRPHKPSLYLELTRKWSEKFSKERMTYALDQQQPAS
What are the official names of this protein?
Glycoprotein endo-alpha-1,2-mannosidase, Endo-alpha mannosidase, Endomannosidase, mEndo.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 99 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: COAA_LACP3
Sequence: MQSEMNYYKFDRAEWSQFHSQNFTNVTDEELAQLRSLNDEISLDDVKMIYSPLRHLIHIRYEDYQGDMFTLSRFLGMQRNPHTPFIIGIAGSVAVGKSTTARLLQLLLSRAYPEKRVQQMTTDGFLYPNAELERRGILDRKGFPESYDMELLIHFMNNVKNASGALRAPKYSHQIYDIVPGEYELIDRPDILIVEGINVLQLPSKQPIYVSDYFDFSIYVDANPDLIEQWYLERFGILLDTAFTDPNNYYYQYAIGDRADAFAMARQVWRDVNLKNLNEYILPTKNRADIILHKTTGHEIDQVSLRKW
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGB_LEPBA
Sequence: MNHQSEKINHILEALPYLINYSGKTIVIKYGGAAMVEEELKASFAEDIVLLKYLGINPVVVHGGGPEINSLIKSLNLNTQFIRGHRVTDEATMEVVEMVLTGKVNKQIVSLIQEKGGKPVGLSGKDGGLAIAEKYLMEVEAEDGKSQKIDLGLVGEITSVDPNIILTLQREGFIPIISPVAMSKEGQTLNINADTMAGAIAQALHADKLILLTDTPGILIDGQLVTGLKKVDIHGYIKTGQISGGMIPKVECCLGAIDSGVKRAHIIDGRVPHSVLIEILTNQGIGSLIEQG
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_ECO24
Sequence: METIAKHRHARSSAQKVRLVADLIRGKKVSQALDILTYTNKKAAVLVKKVLESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RSMH_PROM3
Sequence: MPDSSINSDSGFKHLSVMADAVSQPVAALPAELLDGGLMIDATLGGGGHSALLLERHPDLRLIGLDQDPTARAAAAERLALFGDRVKIVATNFVDFSPAEPAVVVMADLGVSSPQLDVAKRGFSFRLDGPLDMRMNPQVGETAAELIGRLEETELADLIYAYGEERLSRRIARRIKHDLAEQGPYAGTAALAYAVAGCYPPKARRGRIHPATRTFQALRIAVNDELDALDRFLQKAPDWLVPGGLLAVISFHSLEDRRVKTAFLRDQRLERLTRKPLVASEMEIAANPRSRSAKCRFARRLPQAMTADAL
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPF_CYTH3
Sequence: MKIKVGFGYDVHQLKEGRPMWLGGIQLEYTKGPDGHSDADVLIHAICDAILGAANMRDIGFHFANTDDRWKGVDSKVLLKEVCRMIREKGWEISNVDASLALEMPKINPHIERMQTALSEAMSIPVEDISIKATTNEKLGYVGREEGVNAYAVALLIKP
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: SBMC_ENTLS
Sequence: MEYSIRQEQQRVVAGFHMVGPWEQTVKQGFEQLMMWVDGRDIPAKEWLAVYYDNPDEVPAEKLRCDTVVTVEPGFQIPANSEGVMLTQVSGGEYAVASARVVNHDFATPWYQFFGSVLADTAWEMAAKPCFERYLNDGNQDGYWDIEMYIAVSRRAG
What is the function of this protein?
Inhibits the supercoiling activity of DNA gyrase.  Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase.  It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell.
What are the official names of this protein?
DNA gyrase inhibitor.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADC_BURVG
Sequence: MKPSDVRSKAFAMPLTSPAFPMGPYRFVDREFVIITYRTDPERLRAVVPEPLQIAEPLVHYEFIRMADSTGFGDYTESGQVIPVEYNGQAGGYTLAMYLDDHPPIAGGRELWGFPKKLASPTLHVNTDHILGTLDYGKVRVATGTMGYKHKELDLDEQMKRLAGPNFLLKIIPHVDGSARVCELVRYYLQDIKMKGAWTGPASLELAPHALAPVADLPVLEIVEARHIVADLTLGLGEVVYDYLAQ
What is the function of this protein?
Catalyzes the conversion of acetoacetate to acetone and carbon dioxide.
What are the official names of this protein?
Acetoacetate decarboxylase, AAD, ADC.
What is the protein family that this protein belongs to?
Belongs to the ADC family.
Protein: YGIB_ECO24
Sequence: MKRTKSIRHASFRKNWSARHLTPVALAVATVFMLAGCEKSDETVSLYQNADDCSAANPGKSAECTTAYNNALKEAERTAPKYATREDCVAEFGEGQCQQAPAQAGMAPENQAQAQQSSGSFWMPLMAGYMMGRLMGGGAGFAQQPLFSSKNPASPAYGKYTDATGKNYGAAQPGRTMTVPKTAMAPKPATTTTVTRGGFGESVAKQSTMQRSATGTSSRSMGG
What are the official names of this protein?
UPF0441 protein YgiB.
What is the protein family that this protein belongs to?
Belongs to the UPF0441 family.
Protein: RK36_DRIGR
Sequence: MKIRASVRKICEKCRLIRRRGRIIVICFNPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y5435_HAEIG
Sequence: MFGKGGLGGLMKQAQQMQEKMQKMQEEIAQLEVTGESGAGLVKIAINGAHNCRRIDIDPSLMEDDKEMLEDLIAAAFNDAVRRAEELQKEKMASVTAGMPLPPGMKFPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein CGSHiGG_05435.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RPOZ_MARMS
Sequence: MARVTVEDCLENVDNRFELVMVASKRARQLATGGEDAKVPLEGDKVTVVALREIAENLINAKNVDQQKRPLHEF
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: HUTI_XANOR
Sequence: MSCVQQAAQHRSKPRGNTRAIGMPPIAHHPAPAAPDIAYRRATRGEQPAVYQGVVVARQQGRMRCVQLDQISRGTGTDAGVRNAQRLRGTNAGLIVEPASAGYSTLRHYIARLQRQALAVFEQAQFFGCIDQHIRIRAHAEASARRGKCPHREHAVAQIRLGDRAQTDDRAAGDDRLQFVRIHVRGVHQTPARIHRRVGQQPLHRTLPGPGQAGIHFTLLFGDMDVDGAIGERHQRRQLRRGDRTQAVRRQPKHRIRQRFQAVSAVVQQACETIDAVNQAALRRAGSGTAEIRMRIEHRQQAETDAGVGGRGGDALGHFAGMRVRRTAHGVVQIVEFADAGEAAFEHFHIRLFGDRLQAVRIEPVDEAVHQLAPAPEAVAAASADFGQPRHAALEGMAVQIAQARQQHVAARVGQGSSGTGLQRGDAALLCRDPHPARPAVGQQRPGGPEHLHLLVSHWTPSIAELIVYTYQTPRACAMHCDVLWHNAQLMTLDAADGGLGIVDDGTVACQQGRIVYAGPAAQAPALQPHATHDCQRRWISPGLIDCHTHLVYAGNRANEFEQRLRGASYADIAAAGGGIVATVRATRAADDAALLAASLPRLDAMLGEGVTTLEIKSGYGLTLDDEIKQLRVARQLAALRKVEVVPTFLGAHAVPPGGDAQRYTDQVCTQMIPAIAAQGLAEAVDVFCEHLAFSHAQAEQVFIAAQAHGLHIKIHAEQLSNQHGAELAARYGALSADHIEYLDQAGIAAMAGAGTVAVLLPGAFYFTRDTQVPPIAALRAAGVPLALATDCNPGTSPLTSPLLAMNMAATLFRMTVDECIAGFTREAARALGRSERLGRLRAGMDCDLAIWDIDAPADLVYRMGFNPLHARVLRGHLC
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XAGE2_HUMAN
Sequence: MSWRGRSTYRPRPRRSLQPPELIGAMLEPTDEEPKEEKPPTKSRNPTPDQKREDDQGAAEIQVPDLEADLQELCQTKTGDGCEGGTDVKGKILPKAEHFKMPEAGEGKSQV
What are the official names of this protein?
X antigen family member 2, XAGE-2, Cancer/testis antigen 12.2, CT12.2, G antigen family D member 3.
What is the protein family that this protein belongs to?
Belongs to the GAGE family.
Protein: GPDA_THISH
Sequence: MSQPPVAVLGAGSWGTALAMHLARQGHRVRLWGRDPEAMAAMAEANCNTRYLPDAPFPPGLEPTADLDAALRESSCWLVVVPSQAFREMLQKLAPYRDDARVLVWATKGLEEHSGQWLHQVVAEEMGVNFPCAVISGPSFAKEVARGLPTALTVASTTPGVAERVAEWFHGERMRVYLSDDVLGVQLGGAFKNVLAIAAGISDGLGFGANARAALITRGLAELMRLGDAAGARRETLMGLSGLGDLVLTCTDDQSRNRRLGLALGRGESLDAALAAIGQAVEGARTARMAVSKAAELGVDMPICHQVHRVLYVGHSAIEAVGELLGRDQKPEF
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_HELPH
Sequence: MKNRYIQQFEDAQLKDKTMPAFKAGDTLRLGITIKEGEKTRTQYFEGVCIAIRGNGVDKTFCVRKIGANNIGVEKIFPFYSESLASVEVLRVGRVRRAKLYYLRDRRGKAARIKEVRH
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: LOLB_COXB1
Sequence: MSLISNNEERSLRVRYCIAIALSALLISGCTTLRLPNQSTSVYHQQTWAQRYYDLSRISQWNIDGAFSIQQPGKTIIAAYDWQQKGMNYRIRIHSSLDIYSVNISGRPGMVTLWRSPRQHYTASTPEQLMQQQLGWQLPLSNLYYWIRGIPAPGAYQADFDTYTHLIALQQSGWHIRFSQYTTVGSVDLPRTLQLSNGPLAVKIVLKHWQ
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: EFTS_EXISA
Sequence: MAVTAAMVKELREKTGAGMLDCKKALVETDGDMQAAIDFLREKGIAKAAAKGDRIAAEGLTAVAVEGNKAVLVEINSETDFVAKNEKFQTLVNNVAKAVLASGATTAEAALAAEYEAGKTLETYIQEEASTIGEKISLRRVAVLEKAEDAVFGTYLHMGGRIGSVVVIDGTSDETVAKDVAMHVAAASPLYATRDEVSAEEIDREKKVLTEQALNEGKPANIVEKMIAGRMNKYFEEICLVDQTFVKDSDFKVGKYVESKGGKINSFVRFEVGEGMEKREENFAEEVMNQLKK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_SHEPA
Sequence: MTQEFEHLSVLLAETVAGLNIRPDGIYIDGTFGRGGHSRKVLEELGPNGRLIAIDRDPQAIAAAEQFKDDSRFQIVHGGFGQLADYVEDLGLKGQIDGVLLDFGVSSPQLDDAERGFSFLRDGPLDMRMDNSQGETAAQWLARAEIEDMAWVFKTYGEEKNSRHIARCIAADREKAPFLRTKDLADLIARITKNKERNKHPATRVFQAIRIYINSELEQIDQALEGALAVLAPEGRLSVISFHSLEDRMVKRFIRRNSQGESVPHGLPITEAEINKSRKLKAMGKAIKPSVEEVERNARARSSVLRIAERLPYEA
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_SHESA
Sequence: MRVLGIETSCDETGIAVYDDKLGLLSHALYSQVKLHADYGGVVPELASRDHVRKIVPLIRQALKNANTEIADLDGIAYTKGPGLIGALLVGACVGRSLAFAWNKPAIGVHHMEGHLLAPMLEDDAPEFPFVALLVSGGHSMLVKVDGIGLYEVLGESVDDAAGEAFDKTAKLMGLDYPGGPRLAKLAAKGEPAGYQFPRPMTDRPGLDFSFSGLKTFTANTIAAEPDDEQTRANIARAFEEAVVDTLAIKCRRALKQTGYNRLVIAGGVSANTRLRETLAEMMTSIGGRVYYPRGEFCTDNGAMIAFAGLQRLKAGQQEDLAVKGQPRWPLDTLPPVA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_ACTSZ
Sequence: MSLSVEQKAAIVAEFGRDAKDTGSSEVQIALLTAQINHLQSHFAEHKKDHHGRRGLLRMVSRRRKLLDYLKRTDLAKYSEIIARLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: GRPE_CHLTA
Sequence: MTETPNTSSEEIQTSEPSPDNELQVLQQENANLKAELQEQNDRYLMALAEAENSRKRLQKERTEMMQYAVENTLMDFLPPIESMEKALGFASQASEEVKNWAIGFQMILQQFKQIFEEKGVVEYSSKGELFNPYLHEAVEIEETTTIPEETILEEFTKGYKIGDRPIRVAKVKVAKLPAKGNSDSNEEKE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 6PGL_STRCO
Sequence: MSDTPQLVVHRDKELMAEAAAARLITKIVDAQASRGSASVVLTGGRNGNGLLAALAGSPARDAIDWSRLDLWWGDERFLPEGDPERNVTQAQQALLDSVPLDPKRVHAMAASDGPYGSDVEAAAAAYAQELATASVPENHAAVPSFDVLLLGVGPDTHVASLFPEHPGVRETERTVIGVHGSPKPPPIRISLTLPAIRAAREVWLLAAGEDKANAVAMALSGAGEIQAPAAGARGRARTLWLLDSAAASQLPRSLYPPASA
What is the function of this protein?
Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
What are the official names of this protein?
6-phosphogluconolactonase, 6PGL.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
Protein: WDHD1_XENLA
Sequence: MPAIKKNMRYGHPEGHTDVCFDDSGNFLVTCGSDGDIRIWESLDDDDPKSISIGEKAYSFALKNGKVVTAASNNAIQLHTFPDGEPDGILTRFTTNANHVVFNTDGTRIAAGSGDFLVKVLQVEDSTQQKTLRGHSAPVLSVSFDPKDIYLASASCDGSVRIWKISDQTCEAVLPLLEKCNDVFNAKSICRLAWQPKSGKFVAIPVGKAVHLYDRDSLKNICTLSDDFITQPVNIVAWSPCGQYLVAGSVDGCIVAWNIATKACLERIKHEKGYTICALAWHPHLPQIAYTDNEGNLGLLEDVCQGDVKQPSAKVSSAETKDYDELFDGDDDEDFLNGDMIGHEGAVNDEDDDDNFTALTGRPRNRGAIFDDDISSDVPSLKLVGNENPVVEDDQASSVQNFTSVASVKLSYNGPMPTPQQKPFQSGSTPVHLMHRFMVWNSVGVIRCYNDEQDNAIDVEFHDTSIHHAIHLTNSLNHTLADVSQEAVLLACETTEELASKLQCLHFSSWDTSKEWMVDMPKGENIQAICLGQGWVACATSALLIRIFSVGGVQKELISLFGPVVCMASHGEQLIVVYHRGMGFDGDQCLGVQLLELGKKKKQVLHGDPLPLSRKSYLSWLGFTAEGSPCYVDSEGIVRLLNRSLGDTWVPICNTREHCKGKSDHYWVVGIHENPQQVRCIPCKGSRFPPTLPRPAVAVLPFNLPYCQITTEKGQMEEQYWRSQIFSNHSDYLSKHGYECDENFKAEAQKMQQELLMKMFALSCKLEREFRCMELAEFMTQNVMNLAIKYASRSKRLILAQRLSEMALEKAAEQASAEQNEEEDEEEEDFRSRLTAGYSRTATEWGDSRAKPVKQDQYEENNEEEMEEEEKEQEEALESNTPTANPFNKSVKTPDVSESKLGAILSSNQGRVNPFKVSASQKSPAFASNSSRSTSILDNMGKFPRKPSASGSPSTSKSDSVIIKPLAPKAKSKQGQATLFHSVQAKPIAKKTTEEKKAVPTPPKAAADIAENKKPKTGFQLWLDENRPSILSENAGLDESEIIKEGMSRFRMLTSEERMLWTEKAKGDYPGEDGADAKKRKRPEQENMASNGCPQENTDSGIAAAKKHKPLGQSANNKLSAFAFKKE
What is the function of this protein?
Core replisome component that acts as a replication initiation factor.  Binds directly to the CMG complex and functions as a hub to recruit additional proteins to the replication fork.
What are the official names of this protein?
WD repeat and HMG-box DNA-binding protein 1, Acidic nucleoplasmic DNA-binding protein 1, And-1.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Cytoplasm. Note=Transiently cytoplasmic during mitosis.
Protein: CHI1_GINBI
Sequence: GPLQLSWNYNYGAAGK
What is the function of this protein?
Defense against chitin-containing fungal pathogens.
What are the official names of this protein?
Endochitinase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 19 family. Chitinase class I subfamily.
Protein: AKH_LOBRE
Sequence: QVNFTPGW
What is the function of this protein?
This hormone, released from cells in the corpora cardiaca, causes release of diglycerides from the fat body and stimulation of muscles to use these diglycerides as an energy source during energy-demanding processes.
What are the official names of this protein?
Adipokinetic hormone, AKH.
What is the protein family that this protein belongs to?
Belongs to the AKH/HRTH/RPCH family.
What are the subcellular locations of this protein?
Secreted.
Protein: NSP6_ROTRF
Sequence: MNHLQQRQLFLENLLVGVNSTFHQMQKHSVNTCCQSLQKILDHLILLQTIHSPAFRLDRMQLRQMQTLACLWIHQHNHGHQAMLGAIKWISPLIKELV
What are the official names of this protein?
Non-structural protein 6, NSP6.
What is the protein family that this protein belongs to?
Belongs to the rotavirus A NSP6 family.
What are the subcellular locations of this protein?
Host cytoplasm. Host mitochondrion. Note=Found in spherical cytoplasmic structures, called viral factories, that appear early after infection and are the site of viral replication and packaging.
Protein: P10_BPPH6
Sequence: MDNILDPLKAPFSSEAAAKTTAAKIAVVYALVGLVGGLLLTK
What is the function of this protein?
Involved in cell lysis.
What are the official names of this protein?
Envelope protein P10.
What are the subcellular locations of this protein?
Virion membrane; Single-pass membrane protein.
Protein: ATOX1_HUMAN
Sequence: MPKHEFSVDMTCGGCAEAVSRVLNKLGGVKYDIDLPNKKVCIESEHSMDTLLATLKKTGKTVSYLGLE
What is the function of this protein?
Binds and deliver cytosolic copper to the copper ATPase proteins.  May be important in cellular antioxidant defense.
What are the official names of this protein?
Copper transport protein ATOX1, Metal transport protein ATX1.
What is the protein family that this protein belongs to?
Belongs to the ATX1 family.
Protein: PHP1_ORYSJ
Sequence: MDRYAFLSFYKCTHQVGKFVGSDTWSNVLRESWFFNNWKELLVPVSLSTFLLLGLKGYLDEQFCQVEDLQDEASPNFVEEVVTLFFKDSGRLMSNIEQALEKYPRDFNRWDTYMQQLKGSCSSIGASRMKNECMSFRDSCGQGNVEGCMRSFQKVKREHAVLRQKLESYFQLLRQAGPAGAATRPVM
What is the function of this protein?
Functions as two-component phosphorelay mediators between cytokinin sensor histidine kinases and response regulators (B-type ARRs).  Plays an important role in propagating cytokinin signal transduction.
What are the official names of this protein?
Pseudo histidine-containing phosphotransfer protein 1, OsHpt1.
Protein: MSCL_BRUO2
Sequence: MLKEFQEFALKGNMVDLAIGVIIGGAFGGLVNSIVNDIIMPIIGLITGGIDFSNMFIQLAGDPKTTLAAAREAGATIAYGNFITLLINFMIIAWVLFLVVKLMNRLKKREEAKPAPAAPSEEVLLTEIRDILAKQQKA
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DSBA_PSEAB
Sequence: MRNLILTAMLAMASLFGMAAQADDYTAGKEYVELSSPVPVSQPGKIEVVELFWYGCPHCYAFEPTIVPWSEKLPADVHFVRLPALFGGIWNVHGQMFLTLESMGVEHDVHNAVFEAIHKEHKKLATPEEMADFLAGKGVDKEKFLSTYNSFAIKGQMEKAKKLAMAYQVTGVPTMVVNGKYRFDIGSAGGPEETLKLADYLIEKERAAAKK
What is the function of this protein?
Involved in disulfide-bond formation.  Acts by transferring its disulfide bond to other proteins (By similarity).
What are the official names of this protein?
Thiol:disulfide interchange protein DsbA.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. DsbA subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: SILA_SALTM
Sequence: MIEWIIRRSVANRFLVMMGALFLSIWGTWTIINTPVDALPDLSDVQVIIKTSYPGQAPQIVENQVTYPLTTTMLSVPGAKTVRGFSQFGDSYVYVIFEDGTDLYWARSRVLEYLNQVQGKLPAGVSSEIGPDATGVGWIFEYALVDRSGKHDLSELRSLQDWFLKFELKTIPNVAEVASVGGVVKQYQIQVNPVKLSQYGISLPEVKQALESSNQEAGGSSVEIAEAEYMVRASGYLQSIDDFNNIVLKTGENGVPVYLRDVARVQTGPEMRRGIAELNGQGEVAGGVVILRSGKNARDVITAVRDKLETLKASLPEGVEIVTTYDRSQLIDRAIDNLSSKLLEEFFVVAIVCALFLWHVRSALVAIISLPLGLCIAFIVMHFQGLNANIMSLGGIAIAVGAMVDAAIVMIENAHKRLEEWDHRHPGEQIDNVTRWKVITDASVEVGPALFISLLIITLSFIPIFTLEGQEGRLFGPLAFTKTYSMAGAAALAIIVIPILMGFWIRGKIPAETSNPLNRVLIKAYHPLLLRVLHWPKTTLLVAALSIFTVVWPLSQVGGEFLPKINEGDLLYMPSTLPGVSPAEAAALLQTTDKLIKSVPEVASVFGKTGKAETATDSAPLEMVETTIQLKPEDQWRPGMTIDKIIDELDRTVRLPGLANLWVPPIRNRIDMLSTGIKSPIGIKVSGTVLSDIDATAQSIEAVAKTVPGVVSVLAERLEGGRYIDIDINREKASRYGMTVGDVQLFVSSAIGGAMVGETVEGVARYPINIRYPQDYRNSPQALKQMPILTPMKQQITLGDVADINVVSGPTMLKTENARPASWIYVDARGRDMVSVVNDIKTAISEKVKLRPGTSVAFSGQFELLEHANKKLKLMVPMTVMIIFILLYLAFRRVDEALLILMSLPFALVGGIWFLYWQGFHMSVATGTGFIALAGVAAEFGVVMLMYLRHAIEAHPELSRKETFTPEGLDEALYHGAVLRVRPKAMTVAVIIAGLLPILWGTGAGSEVMSRIAAPMIGGMITAPLLSLFIIPAAYKLIWLRRHKKSVS
What is the function of this protein?
Component of the sil cation-efflux system that confers resistance to silver.  May be part of a three-component cation/proton antiporter.
What are the official names of this protein?
Putative cation efflux system protein SilA.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.