PharMolix/UniProtQA huggingface dataset:
Protein: VG76_BPML5
Sequence: MKAWHVVLLMCLAVVLGNLPGIIAEASASPLCEYRSAAHIAEHGGKVADDAWHIKHGELPSCDESPKGEARRDNDNRDGGKSRFCRKRWYC
What are the official names of this protein?
Gene 76 protein, Gp76.
Protein: SPZ1_ARATH
Sequence: MDVREAMKNQTHVAMILSGHVLSSAPKDSNVIFSPASINSAITMHAAGPGGDLVSGQILSFLRSSSIDELKTVFRELASVVYADRSATGGPKITAANGLWIDKSLPTDPKFKDLFENFFKAVYVPVDFRSEAEEVRKEVNSWVEHHTNNLIKDLLPDGSVTSLTNKIYANALSFKGAWKRPFEKYYTRDNDFYLVNGTSVSVPFMSSYENQYVRAYDGFKVLRLPYQRGSDDTNRKFSMYFYLPDKKDGLDDLLEKMASTPGFLDSHIPTYRDELEKFRIPKFKIEFGFSVTSVLDRLGLRSMSMYHKACVEIDEEGAEAAAATADGDCGCSLDFVEPPKKIDFVADHPFLFLIREEKTGTVLFVGQIFDPSGPCSGSNSDSDDY
What is the function of this protein?
Probable serine protease inhibitor.
What are the official names of this protein?
Serpin-Z1, ArathZ1.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
Protein: IBPB_KLEP3
Sequence: MRNYDLSPLLRQWIGFDKLANALQTAGESQSFPPYNIEKSDDNHYRITLALAGFRQEDLDIQLEGTRLVVKGTPQQPEKETTWLHQGLVSQAFSLSFTLADNMEVSGATFTNGLLHIDLTRNEPEQIAPQRIAISERPALNS
What is the function of this protein?
Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress.  Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE.  Its activity is ATP-independent.
What are the official names of this protein?
Small heat shock protein IbpB, 16 kDa heat shock protein B.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHS_AQUAE
Sequence: MVRKLSEEEVKRELENLEGWEFCKDYIQKEFSTKNWKTTIFVVNAIASLAEAQWHHPDLEVSFKKVKVKLTTHEAGGITERDIKLAKSIDELVKEILKH
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: BZAA_EUBLI
Sequence: MTLLEKAKCGEITAEMQYVAEKEGVRPEFICEGVANGDIVILYSSRENIHPVAVGKGLLTKVSASVGMYEEADTVDGEMAKIDAAVKAHADTIMDLSVRGPIEEMREKVLSTVDRPVGTLPMYETLSVAEAKYGTALDMTPDDMFDMIEKQASQGVAFIAVHPGTTLSVIHRAKDEGRIDPLVSYGGSHLIGWMLYNNTENPLYTEFDRLIEICKKYDVVLSFADGMRPGCIADSLDHAQVEELVILGGLVRRAREAGVQVMVKGPGHVPLDEIATTVQLEKKLCYGAPYFVFGCLPTDAAAGYDHITSAIGGAVAAYAGADFLCYVTPAEHIGMPNVDDVYQGVMASRIAAHAGDVAKGHPQAVKWDLDMSVARRAMNWKEQFKLSIDPETAERVWRERSTSFTSECTMCGKYCAMKIVEKYLRAE
What is the function of this protein?
Together with BzaB, catalyzes the conversion of aminoimidazole ribotide (AIR) to 5-hydroxybenzimidazole (5-HBI) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.  Is thus involved in the anaerobic biosynthesis of dimethylbenzimidazole (DMB), the lower axial ligand of vitamin B12 (cobalamin).  Requires BzaB for catalytic activity, as BzaA alone displays no activity.
What are the official names of this protein?
5-hydroxybenzimidazole synthase BzaA, 5-OHBza synthase, HBI synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiC family. 5-hydroxybenzimidazole synthase subfamily.
Protein: KITH_HAEI8
Sequence: MAKLYFYYSTMNAGKSTTLLQSSYNYRERDMSTLVYTAAIDDRFGVGKVTSRIGISQDAFLFRSETNLFDEINEHLKKEKVHCVLVDEAQFLSKQQVYQLSDVVDKLKIPVLCYGLRTDFQAELFEGSKYLLAWADQLEELKTICYCGRKANFVLRLNDQGEVIKEGAQIQIGGNDSYLSVCRLHYKEKCGQI
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14Z_BORT9
Sequence: MAKKSMIVKALRKPKYKTRQKNRCKLCGRPKGYMRDFGMCRICFRNHASAGLIPGVSKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: RL10_DINSH
Sequence: MDRAQKEKLVDELGQIFESSGVVVVAHYAGLTVAEMQDFRARMREAGGSVRVAKNRLAKIALQGKPNEKIGELLTGMTVLAYSEDPVAAAKVADAYAKDNSKYQILGGAMGEDYLDQAGVKAVASMPSREELIAQIASCIGAPASNIAGAIGAPASNIASILSTIEEKAEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: MTAP_CERS4
Sequence: MKTMIGVIGGSGVYEIDGLEDAVWTKVETPWGDPSDEILTGRLDGVPMAFLPRHGRGHVHSPTTVPYRANIDALKRLGVTDLVSVSACGSFREEMAPGDFVIVDQFIDRSFARAKSFFGSGCVAHVSLAHPTCGRLSALCAEAARATGVTVHEGGTYLCMEGPQFSTLAESLLYKSWGCHVIGMTNMPEAKLAREAEICYASVAMVTDYDSWHPHHGEVDITAIIATLGTNADHARGLVAGLPARLGTERDLCPHGCDRALDHALMTAPAKRDPELLAKLDAVAGRVLKG
What is the function of this protein?
Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate.  Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis.  Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine.  Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
What are the official names of this protein?
S-methyl-5'-thioadenosine phosphorylase, 5'-methylthioadenosine phosphorylase, MTA phosphorylase, MTAP.
What is the protein family that this protein belongs to?
Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
Protein: TATA_ECOL6
Sequence: MGGISIWQLLIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDEPKQDKTSQDADFTAKTIADKQADTNQEQAKTEDAKRHDKEQV
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RS11_DEIDV
Sequence: MAKPTKGKAPRRARRNISAGRAYVHASYNNTIVTITDLDGNSVAWSSGGTIGYKGSKKGTPYAAQLAAADAVKKAQQTFGMNIVDVIVRGSGSGREQAIRAIQASGIEVKSIMDDTPVPHNGCRPKKKFRA
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: GBRR2_BOVIN
Sequence: MPYFSRLILFLFCLVVLVESRKPKKRRWTGQLETSKPSHLYKKNPDMTKIRHGKPQPLLRVDDHDFTMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFPSASNKSMTFDGRLVKKIWVPDVFFVHSKRSFIHDTTTDNIMLRVFPDGQVLYSMRITVTAMCNMDFSHFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKERKLQEKFPCMCGMLHSRTMMLDGSYSESEANSLAGYPRSHILPEEERQDKIVVHLALSNESSSSRKKGLLKGQVGLRIFQNTHAIDKYSRLIFPASYIFFNLIYWSVFA
What is the function of this protein?
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.  Rho-2 GABA receptor could play a role in retinal neurotransmission (By similarity).
What are the official names of this protein?
Gamma-aminobutyric acid receptor subunit rho-2, GABA(A) receptor subunit rho-2, GABA(C) receptor.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRR2 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi- pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: DER_BACAN
Sequence: MPKPVIAIVGRPNVGKSTIFNRIVGERVSIVEDIPGVTRDRIYSAGEWLNHEFNIIDTGGIDIGDEPFLTQIRQQAEVAIDEADVIIFMTNGRDGVTAADEEVAKILYRSNKPVVLAVNKVDNPEMRSDIYDFYALGFGEPFPISGTHGLGLGDLLDEAAQHFPKIEEDGYDEDTIRFSLIGRPNVGKSSLVNALLGQERVIVSNVAGTTRDAVDTPYSKDGKDYVIIDTAGMRKKGKVYESTEKYSVLRALRAIERSDVVLVVLDGEEGIIEQDKKIAGYAHDSGRAVVIVVNKWDAVKKDEKTMKAFEENIRAHFQFLEYAPIVFLSAKTRKRTQTLIPVIDEVNESHSIRIQTNVLNDVIMDAVAMNPTPTHNGSRLKIFYATQVAVKPPTFVVFVNDPELLHFSYERFLKNRLRESFGFVGTPIHIIARARD
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: SELO_CLOBB
Sequence: MKNKEVIVNNYLNLENTYIKLPKKLFSEQNPSEVKSAKLEVFNESLASDLGLSEEFLQSDDGVAFFAGNKILEGTVPIAQAYAGHQFGHFTMLGDGRAILIGELKSQNGERFDIQLKGAGRTPYSRGGDGKATLGPMLREYIISEGMYGLGIPTTRSLAVVSTGEDVMREEILQGAVLTRIAKSHIRVGTFQFVSNWGTVEELKALADYTLNRHFKKAEYEGNPYIYLLNEVIKSQAKLISKWQLVGFIHGVMNTDNVTISGETIDYGPCAFMDVYDPDTVFSSIDIKGRYAYGNQPKIGAWNLARFAETLLPLLDKNLEVAVEIAQNSISKYSDLYNKYWYTGMRAKLGIFNEEEEDKKLIQSLLTIMKRFKSDYTNTFRNLTLGNLSDIDVFTSEEFKTWYELWKERLTRQDQSSEESNKLMKKNNPTVIPRNYRVEEALVAAVKDNDYCVMQRLLDVLKDPYDYSNMNEYYSTLPKSTSCAYKTYCGT
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: PQBP1_BOVIN
Sequence: MPLPVALQTRLAKRGILKHLEPEPEEEIIAEDYDDDPVDYEATRLEGLPPSWYKVFDPSCGLPYYWNVDTDLVSWLSPHDPNSVVTKSAKKLRSSNADAEEKLDRSHEKSDRGHEKSDRGHEKSDRSHEKSERNHEKSDRDRERGYDKVDRERERDRDRDRGYDKVDREESKERRHHRREELAPYPKSKKAASRKDEELDPMDPSSYSDAPRGTWSTGLPKRNEAKTGADTTAAGPLFQQRPYPSPGAVLRANAEASRTKQQD
What is the function of this protein?
Intrinsically disordered protein that acts as a scaffold, and which is involved in different processes, such as pre-mRNA splicing, transcription regulation, innate immunity and neuron development.  Interacts with splicing-related factors via the intrinsically disordered region and regulates alternative splicing of target pre-mRNA species.  May suppress the ability of POU3F2 to transactivate the DRD1 gene in a POU3F2 dependent manner.  Can activate transcription directly or via association with the transcription machinery.  May be involved in ATXN1 mutant-induced cell death.  The interaction with ATXN1 mutant reduces levels of phosphorylated RNA polymerase II large subunit.  Involved in the assembly of cytoplasmic stress granule, possibly by participating in the transport of neuronal RNA granules.  Also acts as an innate immune sensor of infection by retroviruses, by detecting the presence of reverse-transcribed DNA in the cytosol.  Directly binds retroviral reverse-transcribed DNA in the cytosol and interacts with CGAS, leading to activate the cGAS-STING signaling pathway, triggering type-I interferon production.
What are the official names of this protein?
Polyglutamine-binding protein 1, PQBP-1, Polyglutamine tract-binding protein 1.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Cytoplasmic granule. Note=Colocalizes with SRSF2 in nuclear speckles (By similarity). Colocalized with POU3F2. Colocalized with ATXN1 in nuclear inclusion bodies. Localizes to cytoplasmic stress granules (By similarity).
Protein: Y14B_ORYSJ
Sequence: MAAAAEDVEFVDYDRDEEEEEDAMDEDDRGGGRGGRALPVPHIVSQGVMRSRGRLLGRSTSVLASNRDRFDSLADAGNPGHGPQRSIEGWILLVSGVKEDAEEDDLYNTFSDFGHVKDLHLNLERRTGYAKGYALVEYESFEEAQTAIKAMNGTQLLTRTVYVDWAFSRGPIQKLTSTRPLHRRSRTPPRRLAALTC
What is the function of this protein?
Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.  The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism.  The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expression machinery and the core components remain bound to spliced mRNAs throughout all stages of mRNA metabolism thereby influencing downstream processes including nuclear mRNA export, subcellular mRNA localization, translation efficiency and nonsense-mediated mRNA decay (NMD).  The MAGO-Y14 heterodimer inhibits the ATPase activity of EIF4A3, thereby trapping the ATP-bound EJC core onto spliced mRNA in a stable conformation.  The MAGO-Y14 heterodimer interacts with the EJC key regulator PYM leading to EJC disassembly in the cytoplasm (By similarity).  EJC core heterodimers play essential roles in plant growth and development, and pollen and seed development (PubMed:25230811, PubMed:24820023).  The MAGO-Y14 heterodimer selectively binds to the UDT1 (UNDEVELOPED TAPETUM 1) pre-mRNA transcript and regulates the splicing of UDT1, a key regulator in stamen development (PubMed:24820023).
What are the official names of this protein?
RNA-binding protein Y14B, OsY14b, RNA-binding protein 8A.
What is the protein family that this protein belongs to?
Belongs to the RBM8A family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Nucleocytoplasmic shuttling protein. Travels to the cytoplasm as part of the exon junction complex (EJC) bound to mRNA.
Protein: RL14_NEOSM
Sequence: MIKKETVLDVADNSGARKVLCIGISGSKKTASIGDVITVSVKKCIPVGKVSAGSIHRAVVVRVKKRSSSSIVVFGDNAVVLLNKQNEMIGTRVFGPTDSLLRRNKGFAKISSLSQEVFQ
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: ATG14_GIBZE
Sequence: MDCDICHRSHDAKRLPFLCTVDARAALYDGRIENVMALIENEDLQKQISDLLDETNAPTKDRKDALQAQQRTAEDRTTQILAAADKLRNDIKAAKEEIQTRRAALSRRKSDIAAVSDGLIERRVKRQKSVERETGMHKYRWTKCADELARTRSFLCIEAAQLYGLKRIKEGSPSKYEYYLGGIPVVDLTAMNSSTPEMISTSLSHICQILILVSHYLSIRLPAAITLPHRDYPRPTIFNLSASYRPGDPVFPSQASVSSPSSTTDTESQRVSRPRPLFIDKPLSQLAKEDPATFSYFIEGVTLLAYNIAWACNTQGVSIGDKALFEDMSNMGRNLYNLLINHQSAGKDPDTLKNEADGQTSRFGQYSHGTTFYHLGGAEGTEFSKTFKLPSPMKLADKLKKKLLSEAPTPDWEVLDDDAWKVEEELADGSQVNKNLLMGDKSSPRRGTSGWMRVKNR
What is the function of this protein?
Required for cytoplasm to vacuole transport (Cvt) and autophagy as a part of the autophagy-specific VPS34 PI3-kinase complex I (By similarity).  This complex is essential to recruit the ATG8-phosphatidylinositol conjugate and the ATG12-ATG5 conjugate to the pre-autophagosomal structure (By similarity).  ATG14 mediates the specific binding of the VPS34 PI3-kinase complex I to the preautophagosomal structure (PAS) (By similarity).  Autophagy is required for proper vegetative growth, asexual/sexual reproduction, and full virulence (PubMed:28894236).  Autophagy is particularly involved in the biosynthesis of deoxynivalenol (DON), an important virulence determinant (PubMed:28894236).
What are the official names of this protein?
Autophagy-related protein 14.
What is the protein family that this protein belongs to?
Belongs to the ATG14 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein.
Protein: PURU_ECOLI
Sequence: MHSLQRKVLRTICPDQKGLIARITNICYKHELNIVQNNEFVDHRTGRFFMRTELEGIFNDSTLLADLDSALPEGSVRELNPAGRRRIVILVTKEAHCLGDLLMKANYGGLDVEIAAVIGNHDTLRSLVERFDIPFELVSHEGLTRNEHDQKMADAIDAYQPDYVVLAKYMRVLTPEFVARFPNKIINIHHSFLPAFIGARPYHQAYERGVKIIGATAHYVNDNLDEGPIIMQDVIHVDHTYTAEDMMRAGRDVEKNVLSRALYKVLAQRVFVYGNRTIIL
What is the function of this protein?
Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).  Provides the major source of formate for the PurT-dependent synthesis of 5'-phosphoribosyl-N-formylglycinamide (FGAR) during aerobic growth.  Has a role in regulating the one-carbon pool.
What are the official names of this protein?
Formyltetrahydrofolate deformylase, Formyl-FH(4) hydrolase.
What is the protein family that this protein belongs to?
Belongs to the PurU family.
Protein: AZPA5_ASPTN
Sequence: MQLLTIVWTSLAAGIMATATPTSLPLCSMVDRPCKCPPGTTFKNLTTYGVIGAPARDVQDIMGSSAVFDLQFQGGLVPSSTKGKDNVPGAVRSFNFSGPAGYYVISEQVCLRLRMNSGHVADVYKLTKWKTSPDGSFNQQYQQSPKPPVVQVPGAGAYHGGWTSIVGQQTVVRNETAIAWKNWRCETGETFPSATSHEGGITNTSAVLEKQGKLTGVSIAAFTIFNEVRDD
What is the function of this protein?
Part of the cluster A that mediates the biosynthesis of azasperpyranones, members of the azaphilone family that exhibit anti-cancer activities (PubMed:31908094).  Azasperpyranones are synthesized by 2 clusters, A and B (PubMed:31908094).  Cluster A is responsible for the production of the polyhydric phenol moiety while the azaphilonoid scaffold is produced by the cluster B (PubMed:31908094).  The non-reducing polyketide synthase ATEG_03629 produces 5-methyl orsellinic acid, which is then reduced to 5-methyl orsellinic aldehyde by the NRPS-like protein ATEG_03630 (PubMed:24412543).  5-methyl orsellinic aldehyde is then first hydroxylated by the FAD-dependent monooxygenase ATEG_03635 and subsequently hydroxylated by the cytochrome P450 monooxygenase ATEG_03631 to produce the unstable polyhydric phenol precursor of azasperpyranones (PubMed:31908094).  On the other hand, the polyketide synthase ATEG_07659 is responsible for producing the 3,5-dimethyloctadienone moiety from acetyl-CoA, three malonyl-CoA, and two S-adenosyl methionines (SAM) (Probable).  The 3,5-dimethyloctadienone moiety is then loaded onto the SAT domain of ATEG_07661 and extended with four malonyl-CoA and one SAM, which leads to the formation of 2,4-dihydroxy-6-(5,7-dimethyl-2-oxo-trans-3-trans-5-nonadienyl)-3-methylbenzaldehyde (compound 8) after reductive release and aldol condensation (Probable).  The FAD-dependent monooxygenase ATEG_07662 is the next enzyme in the biosynthesis sequence and hydroxylates the side chain at the benzylic position of compound 8 (Probable).  In Aspergillus nidulans, afoF, the ortholog of the FAD-dependent oxygenase ATEG_07660, is the key enzyme for the biosynthesis of asperfuranone by catalyzing the hydroxylation at C-8 of to prevent the formation of a six-membered ring hemiacetal intermediate and thus facilitatings the formation of a five-membered ring to produce asperfuranone (Probable).  In Aspergillus terreus, ATEG_07660 is probably not functional, which leads to the formation of the six-membered ring hemiacetal intermediate presperpyranone instead of asperfuranone (Probable).  Finally, ATEG_03636 is involved in the condensation of the polyhydric phenol moiety produced by cluster A and the perasperpyranone precursor produced by cluster B, to yield azasperpyranone A (Probable).  Further modifications of azasperpyranone A result in the production of derivatives, including azasperpyranone B to F (PubMed:31908094).
What are the official names of this protein?
Azasperpyranone A biosynthesis cluster A protein ATEG_03636.
Protein: CYB_MUSIT
Sequence: MTNIRKTHPLTKIINNSFIDLPAPSNISAWWNFGSLLGICLIIQILTGLFLAMHYTSDTATAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFLHVGRGLYYGSYMFTETWNIGIILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIISALAAVHLLFLHETGSNNPSGIPSDSDKIPFHPYYTIKDILGALLLILMLMLLVLFTPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSILVLAIIPLLHTSKQRSMMFRPLSQCLFWLLVADLLTLTWIGGQPVEHPFIIIGQLASILYFMILLVLMPIISIIENNMLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: FAR7_AUSGA
Sequence: ARSDNFVRL
What is the function of this protein?
FMRFamides and FMRFamide-like peptides are neuropeptides.
What are the official names of this protein?
Extended FMRFamide-7, FMRFa-7.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRF amide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RNH2_BACAN
Sequence: MQKVTIQEAEHLLQEIISEEDDRFQILIKDERKGVQKLISKWYKQKELAQKEKEKFLEMSKYENALREKGLTYIAGIDEVGRGPLAGPVVTAAVILPEDFYIPGLNDSKKLSEAKRERFYGEIKAKAIAIGVGIVSPQVIDEINIYQATKQAMLDAIANLSCTPEYLLIDAMKLPAPIPQTSIIKGDAKSISISAASIIAKVTRDRMMKELGEKYPAYGFEQHMGYGTKQHLEAIEAHGVLEEHRKSFAPIKDMIKK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELU_SHESW
Sequence: MPSAIVAAEQYREIFLNQHPMMDVRAPIEFTRGAFPNSTNLPLMLDSEREKVGTCYKQFGQQAAIALGHSLVNGPIKQQRIEAWASYVKANPNAYLYCFRGGLRSQLTQQWLKEAGIEVPYIQGGYKAMRQYLIGVIEAAPTQQPLLSLSGMTGCGKTDFLLQRKEAVDLEGIANHRGSSFGKNIDPQPTQINFENQLAIALLRHQQDNHSCLLLEDESFLIGRSALPQSFYSAMQAAEILVLEEPDDTRLKRLRNEYVHKMYSGFCERLGLEAGFAAFSEYLLQSLMSIRKRLGGKQHQELQDLMQQALNQQISQNDTSLHLVWIHLLLHKYYDPMYQYQLQKKSERVLFKGSHQAMHEWLNNFKSTQ
What is the function of this protein?
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA).  Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
What are the official names of this protein?
tRNA 2-selenouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the SelU family.
Protein: MNN9_SCHPO
Sequence: MRVYNKSRIVGQLLFVALGITFIYYLFTPSVNSNAKVQIENRGGNSYEIYDMNKITESSDPIRNKEEVLILTPIARFYPQYWKNLLELDYPRNLISLGFIVPSSKDGAKVHRELRNAINAVQKGPGDKRFADVKILIQDSDLSSGQSEAERHKFSAQKERRGKLAATRNTLLLSTLKPSTSWVLWLDSDIVETPSTLIQDLAEHNEDVLVANCFQKQGDKLTPYDFNSWVDSQTAQELASHMDRDEILLEGYAELPTYRMLMAKIYEEHKDPSTIMALDGVGTTALLVKASVHRDGALFPTFPFYHLIESEGFAKMAKRLGHGVYGLPYYLVFHHNE
What is the function of this protein?
Required for the addition of the long alpha 1,6-mannose backbone of N-linked glycans on cell wall and periplasmic proteins.
What are the official names of this protein?
Mannan polymerase complex subunit mnn9.
What is the protein family that this protein belongs to?
Belongs to the ANP1/MMN9/VAN1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein. Note=Cis-Golgi. Recycles between endoplasmic reticulum and Golgi.