PharMolix/UniProtQA huggingface dataset:
Protein: RL21_EHRCJ
Sequence: MFAVVETGGKQYKVKEQDVIRIEKLNASVGEEVTLSNVIALTDVNNNIVFTQSATVTASVLEQCRNDKIIIFKKKRRKNYRRKNGHRQYMTVLRVIKINNME
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: TRPC_BACTN
Sequence: MKDILSEIIANKRFEVDLQKQAISIEQLQEGINEVPASRSMKRALASSDSGIIAEFKRRSPSKGWIKQEARPEEIVPSYLAAGASALSILTDEKFFGGSLKDIRTARPLVDVPIIRKDFIIDEYQLYQAKIVGADAVLLIAAALKQEKCQELAEQAHELGLEVLLEIHSAEELPYINSKIDMIGINNRNLGTFFTDVENSFRLAGQLPQDAVLVSESGISDPEVVKRLRTAGFRGFLIGETFMKTPQPGETLQNFLKAIQ
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: RSMG_LAWIP
Sequence: MPISSLVPLTEIRQYCLQLGFSLSDQEIESLRGYLCLLTKWNKVMNLVGFTTWKTICSNLIIDSFHLAIFIRSLSLPTDPLCWDFGSGAGLPGIPLRIIWKEGSYWLVESREKRAIFLKTLLAQYPLTQTYVYCGRVEEFMLANCLSDVALIVSRAFMPWQALLKLIEKKISFKGVIVLLLNDIPKNIDSCWYIQTTYPYSIGGEKRFFVALKKAS
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLIA3_BOTMO
Sequence: MRLILLSSLLLLGIFLANGHEEDPDGKVLNSLIDTLMHLQKLYANLKYSFLTVHRARSFGSGSERMYVTNKEIKNFEALRQICEQAEGHIPSPQLENQNKAFANVLERHGKEAYLVVGDSANFTNWAAGEPNKAAGTCVKADTHGSWHSASCDDNLLVVCEFYFIL
What is the function of this protein?
This phospholipase A2 inhibitor binds directly phospholipase A2 in the presence or absence of calcium.
What are the official names of this protein?
Phospholipase A2 inhibitor clone 03/12, alpha-PLI.
What is the protein family that this protein belongs to?
Belongs to the alpha-type phospholipase A2 inhibitor family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted in plasma.
Protein: IF1_ECOL5
Sequence: MAKEDNIEMQGTVLETLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVTVELTPYDLSKGRIVFRSR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BORC6_RAT
Sequence: MEAARGRLGPEQDLSTGADHQAVTFSGRPSRTLSKPPSARTLSGEEEAESVGVASRHPRPSPKTSSGSIAHRPELDTWEDKPSARATPSGARGSRGTSGSEHTPPPSSWYPEPEPSEDQPSALTVCRRGSPGGVEMNVELPQQEGDDDDDGDDEEAADRAGHSFPSRLQDSRSLDGLSGACGGGGSSSSGEAGAGGGRRATISSPLELEGTVSRHGDLTHFVANNLQLKIRLSGAPSPVPPASGRPCLTPAPTPTIPPIDPDVLRDLERLSRELGGRVDRLLCGLGGAVQELTALSVGCIQTYRDAVDSLGEAVDMSIKGMYTLLARCEELERALQPVQGLARQVRDIRRTLEVLEALCK
What is the function of this protein?
As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery.  Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor.
What are the official names of this protein?
BLOC-1-related complex subunit 6.
What is the protein family that this protein belongs to?
Belongs to the BORCS6 family.
What are the subcellular locations of this protein?
Lysosome membrane.
Protein: ARGE_SHISS
Sequence: MKNKLPPFIEIYRALIATPSISATEEALDQSNADLITLLADWFKDLGFNVEVQPVPGTRNKFNMLASIGQGAGGLLLAGHTDTVPFDDGRWTRDPFTLTEHDGKLYGLGTADMKGFFAFILDTLRDVDVTKLKKPLYILATADEETSMAGARYFAETTALRPDCAIIGEPTSLQPVRAHKGHISNAIRIQGQSGHSSDPARGVNAIELMHDAIGHILQLRDNLKERYHYEAFTVPYPTLNLGHIHGGDASNRICACCELHMDIRPLPSMTLNELNGLLNDALAPVSERWPGRLTVDELHPPIPGYECPPNHQLVEVVEKLLGAKTEVVNYCTEAPFIQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELIIQVIHHFCWH
What is the function of this protein?
Catalyzes the hydrolysis of the amide bond of N(2)-acetylated L-amino acids.  Cleaves the acetyl group from N-acetyl-L-ornithine to form L-ornithine, an intermediate in L-arginine biosynthesis pathway, and a branchpoint in the synthesis of polyamines.
What are the official names of this protein?
Acetylornithine deacetylase, AO, Acetylornithinase, N-acetylornithinase, NAO.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. ArgE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRTI_PARSN
Sequence: MNAHSPAAKTAIVIGAGFGGLALAIRLQSAGIATTLVEARDKPGGRAYVWHDQGHLFDAGPTVITDPDALKELWALTGQDMARDVTLMPVSPFYRLMWPGGKVFDYVNEADQLERQIAQFNPDDLEGYRRFRDYAEEVYQEGYVKLGTVPFLKLGQMLKAAPALMKLEAYKSVHAKVATFIKDPYLRQAFSYHTLLVGGNPFSTSSIYALIHALERRGGVWFAKGGTNQLVAGMVALFERLGGQMLLNAKVARIDTDGPRATGVTLADGRALTADMVASNGDVMHNYRDLLGHTARGQSRAKSLNAKRWSMSLFVLHFGLREAPKDVAHHTILFGPRYKELVNEIFKGPKLAEDFSLYLHSPCTTDPEMAPPGMSTHYVLAPVPHLGRADIDWAVEGPRYADRILASLEERLIPNLRANLTTTRIFTPSDFASELNAHHGSAFSVEPILTQSAWFRPHNRDKTIRNFYLVGAGTHPGAGIPGVVGSAKATAQVMLSDLASA
What is the function of this protein?
This enzyme converts phytoene into lycopene via the intermediaries of phytofluene, zeta-carotene and neurosporene by the introduction of four double bonds.
What are the official names of this protein?
Phytoene desaturase (lycopene-forming), 4-step phytoene desaturase, Phytoene dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the carotenoid/retinoid oxidoreductase family.
Protein: DEOC_CORJK
Sequence: MTHFDRSKVTREAVAAILDATLLKPEASRDDVAALVREATELGCGAVCVSPSMLPLGSVPPSGSLGTDATLRIATVAGFPSGKHASLVKATEARYAAQLGADEIDVVIDVAAALAKDQNALLAELITVREAVPHPLVLKVIVESALLDEEQLRTAVRACVQAGADYVKTSTGFHPAGGASVEAVSIMADELRKLGKLAPFGMGEEERVAAGLVGIKASGGIRDWDAALDMIEAGATRLGVSAAAKVLGA
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAPA_VIBPA
Sequence: MKMTRRAFVKANAAASAAAVAGITLPASAANLIASSDQTKITWDKAPCRFCGTGCSVLVGTQNGKVVATQGDPEAPVNKGLNCIKGYFLSKIMYGQDRLTQPLLRMKDGKYHKDGEFTPVSWDVAFDTMAEKWKASLEKKGPTSVGMFGSGQWTVMEGYAAAKMMKAGFRSNNIDPNARHCMASAVVGFMRAFGIDEPMGCYDDFENADAFVLWGSNMAEMHPVLWTRITDRRLSHPHVRVNVLSTYYHRSFELADHGYIFNPQSDLAIANFIANYIIENDAVNWDFVNKHTNFTQADTDIGYGLRDDDPLQKAAKNPNSGKLTSISFEEYKKSVAPYTVEKASEISGVEKEKLIELAKQYADPNTKVMSLWTMGMNQHTRGVWMNNLVYNIHLLTGKIATPGNSPFSLTGQPSACGTAREVGTFAHRLPADMVVANPKHRQIAEKIWKLPEGTIPPKPGFHAVLQDRMLNDGVLNCYWVQCNNNMQAGPNINTERLPGYRNPENFIVVSDPYPTATAQAADLILPTAMWIEKEGAYGNAERRTQAWYQQVGTVGDAKSDLWQVMEFSKRFKMEEVWPEELLAKAPQYRGKTMYDMLFKNGQVDKFPLEEARELNDDSHHFGFYVQKGLFEEYATFGRGHGHDLAPYDVYHTVRGLRWPVVDGKETQWRFKEGSDPYAKAGSGWDFYGNADGKAKIISAPYEAPPEVPDSEFDLWLCTGRVLEHWHTGTMTRRVPELYKAVPDAVCYMHPEDAKARNVRRGEEVVIANKRGEVRVRVETRGRNRPPKGLVFVPFFDARILINKLILDATDPLSKQTDFKKCPVKITKVA
What is the function of this protein?
Catalytic subunit of the periplasmic nitrate reductase complex NapAB.  Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
What are the official names of this protein?
Periplasmic nitrate reductase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: OMPF_SHIFM
Sequence: MMKRNILAVIVPALLVAGTANAAEIYNKDGNKVDLYGKAVGLHYFSKGNGENSYGGNGDMTYARLGFKGETQINSDLTGYGQWEYNFQGNNSEGADAQTGNKTRLAFAGLKYADVGSFDYGRNYGVVYDALGYTDMLPEFGGDTAYSDDFFVGRVGGVATYRNSNFFGLVDGLNFAVQYLGKNERDTARRSNGDGVGGSISYEYEGFGIVGAYGAADRTNLQEAQPLGNGKKAEQWATGLKYDANNIYLAANYGETRNATPITNKFTNTSGFANKTQDVLLVAQYQFDFGLRPSIAYTKSKAKDVEGIGDVDLVNYFEVGATYYFNKNMSTYVDYIINQIDSDNKLGVGSDDTVAVGIVYQF
What is the function of this protein?
Forms pores that allow passive diffusion of small molecules across the outer membrane.
What are the official names of this protein?
Outer membrane porin F, Outer membrane protein F, Porin OmpF.
What is the protein family that this protein belongs to?
Belongs to the Gram-negative porin family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: UGPC_RHOPB
Sequence: MANVTLRNVRKTYPGGVEAIKGIDFAVGDGQFCVLVGPSGCGKSTLLRMVAGLETITKGEIDIGGRVVNDIEPADRDIAMVFQNYALYPHMSVYNNMAYGLRNRGMPKPEIDSRVREAARILEIGALLERKPKQLSGGQRQRVAMGRAIVRQPKVFLFDEPLSNLDAKLRIAMRVEIRKLQRRLNTTSIYVTHDQLEAMTLADILVVMNGGVVEQIGNPLEIYRKPASTFVASFIGAPPMNLIALEPDEIRAQFAGDVRANTEAGILGIRPEDLLISTEAAASGGLALELVVDAIERVGAETFVYGARSRHGEPVISAKPGELPPGEVIVRVPGQSAPAAGERIMVTAPREKLHLFSADGRRRIDL
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
sn-glycerol-3-phosphate import ATP-binding protein UgpC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. sn-glycerol-3-phosphate importer (TC 3.A.1.1.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS13_ALKMQ
Sequence: MARIAGVDLPREKRVEVGLTYIFGIGRQTSNKILAATGINVDTRIKDLTEEEVNELRKLIDADYQVEGDLRREVSLNIKRLKEIRCYRGIRHTKGLPVRGQKTKTNARTRKGPKRTVGRKKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: NU1M_HIPTE
Sequence: MFMINLLMMIVPILLAVAFLTLVERKVLGYMQLRKGPNVVGPYGLLQPIADAIKLFTKEPLRPLTSSISMFIMAPILALTLALTMWTPLPMPYPLINMNLGILFMLAMSSLAVYSILWSGWASNSKYALIGALRAVAQTISYEVTLAIILLSVLLLSGSFTLPTLITTQEHIWLIVPSWPLAMMWFISTLAETNRAPFDLTEGESELVSGFNVEYAGGPFALFFLAEYANIIMMNIFTTILFLGAFHNPLMPELYTINFVTKSMLLTISFLWVRASYPRFRYDQLMHLLWKNFLPLTLALCMWHVTMPIITAGVPPLT
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: WNT6_XENLA
Sequence: QECKCHGLSGSCTFTTCWKKMPHFREVGDRLLERFNGAFKVMGGNDGKTIIPVGHNIKPPDKQDLIYSAESPDFCQANRKTGSPGTRGRVCNSTALDVGGCDLLCCGRGQREETVVVEENCLCRFHWCC
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Probable developmental protein.  May be a signaling molecule which affects the development of discrete regions of tissues.  Is likely to signal over only few cell diameters.
What are the official names of this protein?
Protein Wnt-6, XWnt-6.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: PYRH_PICTO
Sequence: MKRVVISLGGSIISMEKLNLEFMEEFSRMLGNIKGYDGFGIVVGGGKLARTYISDLRKYNVNDNILDEIGINATRINALAMTTFLDDVNSKIPTTVNDAAEMMHDYRYVVMGGTEPGHTTDTVAMLFAERINADVMINGTSVDGVYTEDPRKNRNAKKIDRMNYDDAIKLSIENSIGAGSNVFMDITSLSIAKRSGIKIFVINGLKIDEYINILYNGTCNGTIIE
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VMA21_DROAN
Sequence: MSNKNKKSGGAGNGAAQKQTRQQSHDSQDYSSFKIVLFYCMLIVFLPVVTFFLLKGFVLDRFFSLSEVKVNIASAVGAVVSLHIALGLYIYRAYFGATGSKAVKED
What is the function of this protein?
Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.
What are the official names of this protein?
Vacuolar ATPase assembly integral membrane protein VMA21 homolog.
What is the protein family that this protein belongs to?
Belongs to the VMA21 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein.
Protein: RIMM_LISMO
Sequence: MEKMYNVGKIVNTHGLIGEIRVIATTDFPEERFQVGNTVYLFEKNSKKPEKLIIRSHRKHKNFDLLMFEGFTGIHQVERMKEGVLKIKETQLTNLEENEFYFHEIIGCTVVTTDGEELGEITEILTPGANDVWVVKGADKKEKLIPYIADVVKEINIDDQKITIEVMEGLLD
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOXP1_XENLA
Sequence: MMTPQVITPQQMQQILQQQVLTPQQLQVLLQQQQALMLQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKEQQQQQQVATQQLAFQQQLLQMQQLQQQHLLTLQRQGLLSIQPGQPTLPLQSLAQGMIPAELQQLWKEVTGSHTADDVVCNNHSTLDLSTTCVSSTAQPKTSLLLNSQASTNGQASVLTLKRESSSHEEYTHNHPLYGHGVCKWPGCETICEDFPSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLSKDKERLQAMMSHLHVKSTEPKASPQPLNLVSSATLSKTASEASPQSLPHTPTTPTAPLTPITQGPSVITTTSIHNVGPIRRRYSDKYNIPISSDFAQNQEFYKNAEVRPPFTYASLIRQGILESPEKQLTLNEIYNWFTRQFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEMEFQKRRPQKISGSPTLIKNIQTSHAYCSPLSAALQASMAENSLPLYTTASMGNPALNSLANAIREDLNGVMEHTSSNGSDSSPGRSPMQGMHQVHVKEEPLDHDDNDGPLSLVTTANHSPDFDRDRDYEDDPVNDDME
What is the function of this protein?
Transcriptional repressor.
What are the official names of this protein?
Forkhead box protein P1, XlFoxP1.
What are the subcellular locations of this protein?
Nucleus.
Protein: NUOD_BART1
Sequence: MAEVNVRNFNINFGPQHPAAHGVLRMVLELDGEVVERVDPHIGLLHRGTEKLMETKTYLQAGPYLDRLDYVAPMNQEHAFVLAIEKLLNIKVPKRGQLIRVLFSEIGRILNHLLNVTTQAMDVGALTPPLWGFEQRERLMIFYERACGARLHANYFRPGGVHQDLPESLVEDIGNFIDPFLVSLEKLDALVTPNRIFKQRNVDIGIVSIDEAWARSFSGVMIRGAGVPWDLRKSQPYECYDEMEFDIPIGKNSDCYDRYLIRMEEMRQSAKIMRQCVERLLGAEKNGPVSSLDRKIVPPKRSEMKSSMEALIHHFKLYTEGFHTPPGEVYVAVEAPKGEFGVYLVSDGTNKPYRVKLRAPGFAHLQAMDFLTRGHMLADATAILGSIDIVFGEVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GAB2_RAT
Sequence: MSGGGGDDVVCTGWLRKSPPEKKLRRYAWKKRWFILRSGRMSGDPDVLEYYKNEHSKKPLRIINLNFCEQVDAGLTFNKKELQDSFVFDIKTSERTFYLVAETEADMNKWVQSICQICGFNQAEESTDSLRNLSSASHGPRSSPAEFSSSQHLLRERKSSAPSHSSQPTLFTFEPPMTSHMQPALSTSAPQEYLYLHQCISRRTENSRSASFSQGTRQKSDTAVQKLAQSNGHCINGVSNQVHGFYSLPKPSRHNTEFKDSTYDLPRSLASHGHTKSSLTGSETDNEDVYTFKMPSNTLCREFGDLLVDNMDVPTTPLSAYQIPRTFTLDKNHNAMTVATSGDSAIAPPPRPPKPSQAETPRWGSPQQKPPIGENSRSVAATIPRRNTLPAMDNSRLHRASSCETYEYPTRGSGESASWSAESPGKTAVGRSDSASSDENYVPMNPGSSTLLAMERAGDNSQSAYIPMGPGPHHFDPLGYPSTALPIHRGPSRGSEIQPPPVNRNLKPDRKAKPTPLDLRNNTVIDELPFKSPVTKSWSRINHTFNSSSSQYCRPISTQSITSTDSGDSEENYVPMQNPVSASPVPSGTNSPAPRKSTGSVDYLALDFQPGSPSPHRKPSTSSVTSDEKVDYVQVDKEKTQALQNTMQEWTDVRQSSEPSKGAKL
What is the function of this protein?
Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways.  Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling.  In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation.  Also involved in the regulation of cell proliferation and hematopoiesis (By similarity).
What are the official names of this protein?
GRB2-associated-binding protein 2, GRB2-associated binder 2, Growth factor receptor bound protein 2-associated protein 2.
What is the protein family that this protein belongs to?
Belongs to the GAB family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane.
Protein: DNLJ_THENN
Sequence: MFRGGEKMRQIPKEVIEEVERLREEIEYHNYRYYVLNDPVITDEEYDRLMRRLIELERMYPELVTPDSPTQRVGGKVLEGFKTVKHSVPMLSLDNTYNEEEIIEFDKRVKKTLQESEVEYVAELKIDGVSIALRYENGRFVLGATRGDGVEGEDVSENVKTIRSVPLRLRKPLTIEVRGEIYMPVDEFKRLNEEREEEGLPPFANPRNAAAGTLRQLNTALVASRRLDSFIYYVVHPENYGLKTQWEALQFLKEIGFKVNPHSRLCKNIQEVIEYWREWKERKRELDYWVDGVVVKVNRFDFQKVLGETSKAPRWAIAFKFPAEQARTRILDVTIQVGRTGVLTPVAELEPVQLAGTIVKRASLHNFEYIREKDIRIGDYVFVEKAGGIIPQIVKSIPELRTGSEKEIKPPQSCPVCGGKVGKLSPDEVAIRCLNPHCPAKLKRALRTFVSREALDIEGLGEKIIDRLVDSGLVKDIADIFYLTPFDLAQLGPGIGQRTIAKILQEIEEAKKRPLHKLITGLGIPMVGQKTAKILAEHFKSLEAIAEASYETLKDIPGIGPEIARSIVEYFRNPKTREIIEKLKKAGVKLEEKTVKYDVLKGLTFAVTGTLKNFTREEIIEFLERLGARVVNSVSKNTDYLIVGENPGSKYEKAKALKVKTMSEEEFLRFVENRAKLKGYNFDEIMRGWKEWS
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: ASCL2_MOUSE
Sequence: MEAHLDWYGVPGLQEASDACPRESCSSALPEAREGANVHFPPHPVPREHFSCAAPELVAGAQGLNASLMDGGALPRLMPTSSGVAGACAARRRQASPELLRCSRRRRSGATEASSSSAAVARRNERERNRVKLVNLGFQALRQHVPHGGANKKLSKVETLRSAVEYIRALQRLLAEHDAVRAALAGGLLTPATPPSDECAQPSASPASASLSCASTSPSPDRLGCSEPTSPRSAYSSEESSCEGELSPMEQELLDFSSWLGGY
What is the function of this protein?
AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system.
What are the official names of this protein?
Achaete-scute homolog 2, ASH-2, mASH-2, mASH2.
What are the subcellular locations of this protein?
Nucleus.
Protein: BAG5_ARATH
Sequence: MKRSRKFSSSTTTTTVIHTFYNDHTTPPATKEIPIETPLPATKANVKTNATAAAARIQSGYRSYRIRNLYKKISSINREANRVQSIIQRQETVDAIRSDEKERLRMNETLMALLLKLDSVPGLDPTIREARRKVSRKIVGMQEILDSISETKDEIQWWNYNDLGGVDSGQGGGAWPLYWEEAVEEEMCRERGGEEMERFCAQYLGFRCFQRFLRE
What is the function of this protein?
Co-chaperone that regulates diverse cellular pathways, such as programmed cell death and stress responses.
What are the official names of this protein?
BAG family molecular chaperone regulator 5, mitochondrial, Bcl-2-associated athanogene 5.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CYB_ORYLE
Sequence: MTNIRKTHPLMKIVNNAFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFMHVGRGLYYGSYTFLETWNVGVILLFATMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAMVHLLFLHETGSNNPTGITSDTDKIPFHPYYTIKDILGALLLILVLMLLVLFAPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILVLVPALHMSKQRSMMFRPISQCIFWILVADLLTLTWIGGQPVEHPYIIIGQLASIMYFLLILVLMPVASVIENNFLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: COBS_LISW6
Sequence: MKTLILLIQFFTRIPIPIAINMDEVNLKKGSALLPFVGLIIGAWNWLVFTLVALVMPLPVAIIAGLFAEIIITGGFHVDALADTADGLFSSRKKERMLEIMKDSRVGANGVIAICFYFLFYGALFLSVPSAYEIGWLFFVLPIVAKGVTMLLFAKMTYAGSNEGLGSIFLGVPWWPIAISQLFVLFILGLVFSYIGLLAYAGVILFTIIYRTFVYKRIGGMNGDTLGAGGQMGQLVCLFCLVLVWGLI
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AB21B_ARATH
Sequence: MDSVIESEEGLKVDSPNRADAETSNSKIHEEDEKELKTESDLKEEKKKTEKNKQEEDEKTKTVPFHKLFAFADSFDIILMILGTIGAVGNGLGFPIMTILFGDVIDVFGQNQNSSDVSDKIAKVALKFVYLGLGTLVAALLQVSGWMISGERQAGRIRSLYLQTILRQDIAFFDVETNTGEVVGRMSGDTVLIQDAMGEKVGKAIQLVSTFIGGFVIAFTEGWLLTLVMVSSIPLLVMSGAALAIVISKMASRGQTSYAKAAVVVEQTVGSIRTVASFTGEKQAISNYNKHLVSAYRAGVFEGASTGLGLGTLNIVIFCTYALAVWYGGKMILEKGYTGGQVLIIIFAVLTGSMSLGQASPCLSAFAAGQAAAYKMFEAIKRKPEIDASDTTGKVLDDIRGDIELNNVNFSYPARPEEQIFRGFSLSISSGSTVALVGQSGSGKSTVVSLIERFYDPQSGEVRIDGINLKEFQLKWIRSKIGLVSQEPVLFTSSIKENIAYGKENATVEEIRKATELANASKFIDKLPQGLDTMVGEHGTQLSGGQKQRIAVARAILKDPRILLLDEATSALDAESERIVQEALDRIMVNRTTVVVAHRLSTVRNADMIAVIHQGKIVEKGSHSELLRDPEGAYSQLIRLQEDTKQTEDSTDEQKLSMESMKRSSLRKSSLSRSLSKRSSSFSMFGFPAGIDTNNEAIPEKDIKVSTPIKEKKVSFFRVAALNKPEIPMLILGSIAAVLNGVILPIFGILISSVIKAFFKPPEQLKSDTRFWAIIFMLLGVASMVVFPAQTIFFSIAGCKLVQRIRSMCFEKVVRMEVGWFDETENSSGAIGARLSADAATVRGLVGDALAQTVQNLASVTAGLVIAFVASWQLAFIVLAMLPLIGLNGYIYMKFMVGFSADAKRMYEEASQVANDAVGSIRTVASFCAEEKVMKMYKKKCEGPMRTGIRQGIVSGIGFGVSFFVLFSSYAASFYAGARLVDDGKTTFDSVFRVFFALTMAAVAISQSSSLSPDSSKASNAAASIFAVIDRESKIDPSDESGRVLDNVKGDIELRHISFKYPSRPDVQIFQDLCLSIRAGKTIALVGESGSGKSTVIALLQRFYDPDSGQITLDGVEIKTLQLKWLRQQTGLVSQEPVLFNETIRANIAYGKGGDATETEIVSAAELSNAHGFISGLQQGYDTMVGERGVQLSGGQKQRVAIARAIVKDPKVLLLDEATSALDAESERVVQDALDRVMVNRTTVVVAHRLSTIKNADVIAVVKNGVIVEKGKHETLINIKDGVYASLVQLHLSAST
What are the official names of this protein?
ABC transporter B family member 21, ABC transporter ABCB.21, AtABCB21, Multidrug resistance protein 17, P-glycoprotein 21.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.