PharMolix/UniProtQA huggingface dataset:
Protein: YHHT_ECOLI
Sequence: METPQPDKTGMHILLKLASLVVILAGIHAAADIIVQLLLALFFAIVLNPLVTWFIRRGVQRPVAITIVVVVMLIALTALVGVLAASFNEFISMLPKFNKELTRKLFKLQEMLPFLNLHMSPERMLQRMDSEKVVTFTTALMTGLSGAMASVLLLVMTVVFMLFEVRHVPYKMRFALNNPQIHIAGLHRALKGVSHYLALKTLLSLWTGVIVWLGLELMGVQFALMWAVLAFLLNYVPNIGAVISAVPPMIQVLLFNGVYECILVGALFLVVHMVIGNILEPRMMGHRLGMSTMVVFLSLLIWGWLLGPVGMLLSVPLTSVCKIWMETTKGGSKLAILLGPGRPKSRLPG
What are the official names of this protein?
Putative transport protein YhhT.
What is the protein family that this protein belongs to?
Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y6165_DICDI
Sequence: MTILKSISSMGISNRKNSFSFVSTNSMIETNQNVNSVSKSGYSKLIKGAALMAEGISGFF
What are the official names of this protein?
Uncharacterized protein DDB_G0276165.
Protein: YA026_YEAST
Sequence: MILLKREVSTVNYKMLRRTPLMTIMDWEVTTLKVQNRSLKIHLLMVIKIQIDSVLREMIFHLIYEAQKQRAEDKKYKNKNKIKRKVIITITEICTFTIKYIRYIEVIILSHHFVIGFSFLLGLLRLGTYLMSSRPMQHMYINNFT
What are the official names of this protein?
Putative uncharacterized membrane protein YAL026C-A.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CAPZA_GIBZE
Sequence: MSDIETVSSFVEGAPPGELADVIADIKSLTLETNPDIVNSLTPAFEKYNEEQFVTVKLPGSSQPVIISSYNSLGDGRYFDVESSSSFTFDHTTQKASAVQSHVLEGAQADLVKSTLKSIGPYVDEHFANAAHGVYPIESDSKIAIVIVGNKYSPNNFWNGRWRSLYILDPSSGALEGSLKVDVHYYEDGNVRLLTNKPVSSTISSANGAGIVREISAMEKRYQEELNKGFVSLSEGAFKGLRRQLPVTRQKIEWDRVTSYRLGQDIGNGGSRR
What is the function of this protein?
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends.  Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity).
What are the official names of this protein?
F-actin-capping protein subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the F-actin-capping protein alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Septum.
Protein: SYDND_PROMT
Sequence: MRNKTCGELRASAISANVQLCGWVDRRRDHGGVIFIDLRDRSGTIQITVDPDQGQDLFSIAESLRNETVLQINGLVRARPDEAINTKIPTGEVEVLAKNIKILNTVTSTLPFSVSIHDEESVKEEIRLKHRYLDLRRERMNNNLRLRHNTVKAARSFLENEGFIEVETPILTRSTPEGARDYLVPSRVCGGEFFALPQSPQLFKQLLMVGGVERYYQVARCFRDEDLRADRQPEFTQLDIEMSFMEEKEIIELNEKLIVSIWKKIKGIDLQTPFPRMTWQEAMDRFGTDRPDTRYGMELVNTSDLFSKSGFKVFSNAISSGGCVKCITIEDGNNLISNVRIKPGGDIFSEAQKAGAGGLAFIRVRDDKEVDTIGAIKDNLTTSQIKELLLKTQAKPGDLILFGAGPTNIVNRTLDRVRQFIAKDLKIISDNELKTQWNFLWVTDFPMFEFNSDENRLEAIHHPFCAPKPEDIGESESLWKDKLPNSNAQAYDLVLNGLEIGGGSLRIHNSELQKTVLEVIGLSKNEAEEQFGFLIDALAMGAPPHGGIAFGLDRIVMLLANEDSIRDTIAFPKTQQARCSMAKAPANVENKQLEDLHIASTWIDPD
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBQ_ROSCS
Sequence: MTAPVIMVLGTASSVGKSVLVTALCRLARQRGLRVAPFKAQNMSNNAAVTADGREIARSVAVQAAAAQIEPTVEMNPILIKPEGQRRSQIVVEGRPWRTLDALDFWRRKEMLWEIVTRNLDALRARCDLVIAEGAGSPVELNLKAGDIVNMRVARYVGARCVLVGDIDTGGIFAQLLGTLMLLEPEERELVQGLLVNRFRGDPALFEDGVRILEQRSGLPVLGVIPWFEDLHLPEEDAVALERGNRLARDGLTIAVIHLPAIANFDDFDPLAREPGVTLRYITHPDDLSDAVAVILPGTKHTLAARRWLRERGFDVALHQFPGSIVGICGGYQLLGERISDPLGVEGQGGDEPGLGLLPVETIFSAAKLTVQADAVSRAPWAVGARLHGYEIHMGRTRSIDADRPLITVTQRGADAVEEHDGHISKDGRVWGCYLHGIFANDAFRRGWLQHLGWHPGEELNPSTDPFDHLAQHVAAAIGEKQVRWLFDIG
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: ERPA_PSYA2
Sequence: MNQPANQFNPSSSQPVDPTVLNLTDSAAQKVRRLREEEGDSNLMLRVYVTGGGCSGFSYGFNFANELNEDDANFDNNDVTLVVDSLSYQYLQGSTVDYTEGLEGARFIVTNPNATTTCGCGSSFSI
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: Y096_RICPR
Sequence: MLLKIAHLVGKHTIKFAQSVGIFSLFSFIAISSIIKPPLYLSLIIRQLLFIGFHSLPVVAMTTFFSGAVLALQSYTGFSRFSAENSIATVVVLSLTRELGPVLAGLIVAGRVGASIAAEIATMRVTEQVDALYTLSTDPIKYLVCPRVIAAIITMPCLVLIGDIIGVMGGYLVGIYKLDFNSTAYLTSTFQYLEPIDVISGLIKATVFGFIISIISCYSGYYSGKGAKGVGRATTSAVVNSSILILISNYLITELFFKV
What is the function of this protein?
Could be part of an ABC transporter complex.
What are the official names of this protein?
Probable ABC transporter permease protein RP096.
What is the protein family that this protein belongs to?
Belongs to the MlaE permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SH2B3_RAT
Sequence: MAGRTQGKHRPRVRTCPSLVPFDNPCWPPSHQPLPLQVGAPGHRVTSFLSGRAWPSYIPKGKHGLPGPRYVPDPWSLGVLGHVAPLRVTTTIFLPGASPGVMLDPACQKTDHFLSCYPWFHGPISRVRAAQLVQLQGPDAHGVFLVRQSESRRGEYVLTFNLQGRAKHLRLVLTERGQCRVQHLHFPSVVDMLRHFQRSPIPLECGAACDVRLSGYVVVVSQAPGRKPKVVSRGGVTASTARTKLPSWLRLLHGVIHVISPGSSNTVLFPFSLPHWDSELGHPHLSSAGCPPGHGAEALRGQVTPPEQIFHLVPSPEELANSLRQLELESVSSARDSDYEMDSSSRSHLRAIDNQYTPLSQLCREANL
What is the function of this protein?
Links T-cell receptor activation signal to phospholipase C-gamma-1, GRB2 and phosphatidylinositol 3-kinase.
What are the official names of this protein?
SH2B adapter protein 3, Lymphocyte adapter protein, Lymphocyte-specific adapter protein Lnk, Signal transduction protein Lnk.
What is the protein family that this protein belongs to?
Belongs to the SH2B adapter family.
Protein: VME1_BRV1
Sequence: MFETNYWPFPDQAPNPFNAQVEQLSATENVYIFLTTLFGILQLVYVIFKLLCTMFPALHWSPIWRGLENFWLFLSLASLAIAYWWLPSMTFTGYWALTIIATILGLIMLIMMSVKFVSFVKLFYRTGSFAIAIRGPIVLVALDVTIKLHCTPFAILVKEVGNIFYLSEYCNKPLTAAQVAALRICVGGQWFAYTRSTTTSAAKVAAANSTAKYHLFVLQGVAEYTQLSSVKFE
What is the function of this protein?
Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.
What are the official names of this protein?
Membrane protein, M protein, E1 glycoprotein, Matrix glycoprotein, Membrane glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the torovirinae M protein family.
What are the subcellular locations of this protein?
Virion membrane; Multi-pass membrane protein. Host Golgi apparatus membrane; Multi-pass membrane protein.
Protein: EFG_SHIB3
Sequence: MARTTPIARYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAATTAFWSGMAKQYEPHRINIIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQPQSETVWRQANKYKVPRIAFVNKMDRMGANFLKVVNQIKTRLGANPVPLQLAIGAEEHFTGVVDLVKMKAINWNDADQGVTFEYEDIPADMVELANEWHQNLIESAAEASEELMEKYLGGEELTEAEIKGALRQRVLNNEIILVTCGSAFKNKGVQAMLDAVIDYLPSPVDVPAINGILDDGKDTPAERHASDDEPFSALAFKIATDPFVGNLTFFRVYSGVVNSGDTVLNSVKAARERFGRIVQMHANKREEIKEVRAGDIAAAIGLKDVTTGDTLCDPDAPIILERMEFPEPVISIAVEPKTKADQEKMGLALGRLAKEDPSFRVWTDEESNQTIIAGMGELHLDIIVDRMKREFNVEANVGKPQVAYRETIRQKVTDVEGKHAKQSGGRGQYGHVVIDMYPLEPGSNPKGYEFINDIKGGVIPGEYIPAVDKGIQEQLKAGPLAGYPVVDMGIRLHFGSYHDVDSSELAFKLAASIAFKEGFKKAKPVLLEPIMKVEVETPEENTGDVIGDLSRRRGMLKGQESEVTGVKIHAEVPLSEMFGYATQLRSLTKGRASYTMEFLKYDEAPSNVAQAVIEARGK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEAT3_HUMAN
Sequence: MGKSRTKRFKRPQFSPTGDCQAEAAAAANGTGGEEDDGPAAELLEKLQHPSAEVRECACAGLARLVQQRPALPGLARRDAVRRLGPLLLDPSLAVRETAAGALRNLSACGGFEVCDDMVTKDIMTPLVALLKECSAGLDSNEMSLQEKKDQNRNSIENIANETVNVLWNICECSSRAVSIFNKEGCLEIVLKYLSRFPTNVDLAISVAYCLQTVTEDNPELLKSFSATALNMLESALLSPVSSMESLLLKTLVAGTIWNLKDIIPCKSQAEIINALLKILSEVLGMDAGEMVIQMKEAETQRLKTAAEAEEILENTNGDDLIEDDEMEGISHKRRVRRKTFVSDLLPPTDKELRETIALLTAQQTALEIIVNMCCNEDPSDDEWEELSSSDESDAFMENSFSECGGQLFSPLCLSHEVHTALTNYLIPKKIFEKTAFPNSIAVDLCSRNPTWKPLIRKMNTIQCRALFCLQSLVSLLDVEHLGGAAALQTLAQHLSQLLFSQPDFAKHVDFLEAISSALRALLQTMASKNISQCMTPDQLMTLCKAGIHSSNVGVRVNVVSILGITGSVLAKEDGTLETLKNIGCFLLEVTTKDPSLVVAGEALDALFDVFADGKEAERASIQIKLLSALKEFQPVFKMKIRKEGRGNYSTDQLCVLDNVKMNLRRFIAYQETVEKRLTS
What is the function of this protein?
Plays a role in ribosome biogenesis and in nuclear import of the 60S ribosomal protein L5/large ribosomal subunit protein uL18 (RPL5) (PubMed:35213692).  Required for proper erythrocyte maturation (PubMed:35213692).
What are the official names of this protein?
HEAT repeat-containing protein 3.
Protein: SECA_ACIBS
Sequence: MLASLIGGIFGTKNERELKRMRKIVEQINALEPTISALSDADLSAKTPEFKQRYNNGESLDKLLPEAFAVCREAAKRVMGMRHYDVQLIGGITLHEGKIAEMRTGEGKTLMGTLACYLNALSGEGVHVITVNDYLAQRDAELNRPLFEFLGLSIGTIYSMQEPAEKAAAYLADITYGTNNEFGFDYLRDNMVFSLAEKKQRGLHYAIIDEVDSILIDEARTPLIISGQSEDSSHLYTAINTIPPKLRPQKEEKVADGGHFWIDEKQRSVEMTEIGYETVEQELIQMGLLAEGESLYSATNLNLVHHVSAAIRAHVLFQRDVHYIIHDGEVVIVDEHTGRTMPGRRWSEGLHQAVEAKEGLAIQPENQTLATTTFQNYFRPYKKLSGMTGTADTEAAEMKEIYGLDVVIIPTHRPMIRNDQNDLIYLNRNGKYNAIIQEIMNIRQQGVAPILIGTATIEASEILSSKLKQAGIHHEVLNAKQHEREADIIAQAGSPNAVTIATNMAGRGTDIILGGNWKAKLAKLENPTPEDEARLKAQWEQDHEDVLQAGGLHIIGSERHESRRIDNQLRGRAGRQGDPGVSRFYLSLEDDLMRIFAGDRVVAMMRAMGLKEDEAIEHKMVSRSIENAQRKVEARNFDIRKNLLKYDDVNNEQRKIIYSQRDEILAENTLQEYVEEMHREVMQAMIANFIPPESIHDQWDVEGLENALRIDLGIELPVQEWLEQDRRLDEEGLVERISDEVIARYRQRRAQMGDESAAMLERHFVLNSLDRHWKDHLAAMDYLRQGIHLRGYAQKNPEQEYKKESFNLFVNMLGVIKTDVVTDLVTDLSRVHIPTPEELAEMEAQQQQQAEAMKLSFEHDDVDGLTGEVTASQEALNESATEQQTFPVPESRNAPCPCGSGLKYKQCHGKI
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: NLTP1_FOEVU
Sequence: AIDCKTVDAALVPCVPYLTGGGTPTTQCCSGVSSIKTMAGTPQDKKDACNCVKAAANRYPNIRDDVAQALPVKCNVQLDIPVSRTTNCDAI
What is the function of this protein?
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes (By similarity).  May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues (By similarity).  Binds to both saturated and unsaturated lipids, with the highest binding efficiency for linoleic acid, followed by linolenic acid (PubMed:33277525).
What are the official names of this protein?
Non-specific lipid-transfer protein 1, FvLTP1, nsLTP.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
Protein: LPXD_PSEPK
Sequence: MSVTMTLGQLAEVLGATLKGPEALQITGLATLQEAGPTQLSFLANPQYRKYLDNSQAGAVLLKAADAESFAGNTLVVADPYLAYARISHLFDPKPKAEAGIHPSAVVAEDAQVDASASIGPFAVIESGARIGANVSIGAHCFIGARCVVGEGGWLAPRVTLYHDVTIGKRVVIQSGAVIGGEGFGFANEKGIWRKIAQIGGVTIGDDVEIGVNTAVDRGALSDTRIGDGVKLDNQIQIAHNVQIGDHTAMAACVGISGSTRIGKHCMLAGGVGLVGHIDICDNVFVSGMTMVTRSITEPGSYSSGTAMQPLADWRKSAARIRHLDDMAKRLQQLEKRVDTVTSGGLPTSEG
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: SYR_SHIFL
Sequence: MNIQALLSEKVRQAMIAAGAPADCEPQIRQSAKVQFGDYQANGMMAVAKKLGMAPRQLAEQVLTHLDLNGIASKVEIAGPGFINIFLDPAFLAEHVQQALASDRLGVATPEKQTIVVDYSAPNVAKEMHVGHLRSTIIGDTAVRTLEFLGHKVIRANHVGDWGTQFGMLIAWLEKQQQENAGEMELADLEGFYRDAKKHYDEDEEFAERARNYVVKLQSGDEYFREMWRKLVDITMTQNQITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKGLAVESEGATVVFLDVFKNKEGEPMGVIIQKKDGGYLYTTTDIACAKYRYETLHADRVLYYIDSRQHQHLMQAWAIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRAGGTVKLADLLDEALERARRLVAEKNPDMPADELEKLANAVGIGAVKYADLSKNRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVLSVFRKAEINEEQLAAAPVIIREDREAQLAARLLQFEETLTVVAREGTPHVMCAYLYDLAGLFSGFYEHCPILSAENEEVRNSRLKLAQLTAKTLKLGLDTLGIETVERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FKTN_MOUSE
Sequence: MSRINKNVVLALLTLTSSAFLLFQLYYYKHYLSARNGPGSSKSKGNRVGFDSTQWRAVKKFIMLTSSQNVPVFLIDPWILESINKNFEQVKNASQGPASECRFFCVPRDFTAFALQYHLWKNEDGWFRIAENMGFQCLKTESKDPRLDGIDSLSGTEIPLHYVCKLTTHAIHLVVFHERSGNYLWHGHLRLKGHMDRKFVPFRKLQFGRYPGAFDRPELQQVTVDGLDMLIPKDPGRFLEEVPHSRFIECRYKEARAFLQQYIDDNTVDAMVFRKRAKELLQLAAKTLKDLGVPFWLSSGTCLGWYRQCGIIPYSKDVDLGIFIQDYKPDIILAFQEAGLPLKHKFGKVEDSLELSFQGKNDVKLDIFFFYEEADHLWNGGTQARTGKKFKYLFPKFTLCWTEFVDIKVHVPCETVDYIEANYGKTWKIPIKTWDWKSSPPNVQPNGIWPISEWDEVIQLY
What is the function of this protein?
Catalyzes the transfer of CDP-ribitol to the distal N-acetylgalactosamine of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1) (PubMed:12471058).  This constitutes the first step in the formation of the ribitol 5-phosphate tandem repeat which links the phosphorylated O-mannosyl trisaccharide to the ligand binding moiety composed of repeats of 3-xylosyl-alpha-1,3-glucuronic acid-beta-1 (By similarity).  Required for normal location of POMGNT1 in Golgi membranes, and for normal POMGNT1 activity (PubMed:19017726).  May interact with and reinforce a large complex encompassing the outside and inside of muscle membranes (PubMed:19017726, PubMed:22922256).  Could be involved in brain development (Probable).
What are the official names of this protein?
Ribitol-5-phosphate transferase FKTN, Fukutin, Fukuyama-type congenital muscular dystrophy protein, Ribitol-5-phosphate transferase.
What is the protein family that this protein belongs to?
Belongs to the LicD transferase family.
Protein: GATC_SYNC1
Sequence: MKINREQVEHVARLARLALSEDELASLTDDMDAILGYVEKLNELDTDHIIPTAHAVPVENAFREDCAGSSIGTDKALQNAPEASDNCFVVPKVIE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: RTBDN_HUMAN
Sequence: MDCRVHMRPIGLTWVLQLTLAWILLEACGGSRPLQARSQQHHGLAADLGKGKLHLAGPCCPSEMDTTETSGPGNHPERCGVPSPECESFLEHLQRALRSRFRLRLLGVRQAQPLCEELCQAWFANCEDDITCGPTWLPLSEKRGCEPSCLTYGQTFADGTDLCRSALGHALPVAAPGARHCFNISISAVPRPRPGRRGREAPSRRSRSPRTSILDAAGSGSGSGSGSGP
What is the function of this protein?
Riboflavin-binding protein which might have a role in retinal flavin transport.
What are the official names of this protein?
Retbindin.
What is the protein family that this protein belongs to?
Belongs to the folate receptor family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix, interphotoreceptor matrix. Cell membrane; Peripheral membrane protein.
Protein: AT1B1_CHICK
Sequence: MARGKANDGDGNWKKFIWNSEKKELLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTVSEFEPKYQDRVAPPGLTQVPQVQKTEISFTVNDPKSYDPYVKNLEGFLNKYSAGEQTDNIVFQDCGDIPTDYKERGPYNDAQGQKKVCKFKREWLENCSGLQDNTFGYKDGKPCILVKLNRIIGFKPKAPENESLPSDLAGKYNPYLIPVHCVAKRDEDADKIGMVEYYGMGGYPGFALQYYPYYGRLLQPQYLQPLVAVQFTNLTYDVEVRVECKEYGQNIQYSDKDRFQGRFDIKFDIKSS
What is the function of this protein?
This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.  The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.
What are the official names of this protein?
Sodium/potassium-transporting ATPase subunit beta-1, Sodium/potassium-dependent ATPase subunit beta-1.
What is the protein family that this protein belongs to?
Belongs to the X(+)/potassium ATPases subunit beta family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: T2R39_PANTR
Sequence: MLGRCFPPDTKEKQQLRMTKLCDPAESELSPFLITLILAVLLAEYLIGIIANGFIMAIHAAEWVQNKAVSTSGRILVFLSVSRIALQSLMMLEITISSTSLSFYSEDAVYYAFKISFIFLNFCSLWFAAWLSFFYFVKIANFSYPLFLKLRWRITGLIPWLLWLSVFISFSHSMFCINICTVYCNNSFPIHSSNSTKKTYLSEINVVGLAFFFNLGIVTPLIMFILTATLLILSLKRHTLHMGSNATGSNDPSMEAHMGAIKAISYFLILYIFNAVALFIYLSNMFDINSLWNNLCQIIMAAYPAGHSILPIQDNPGLRRAWKRLQLRLHLYPKEWTL
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 39, T2R39.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GNA13_HUMAN
Sequence: MADFLPSRSVLSVCFPGCLLTSGEAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDFDQRAREEFRPTIYSNVIKGMRVLVDAREKLHIPWGDNSNQQHGDKMMSFDTRAPMAAQGMVETRVFLQYLPAIRALWADSGIQNAYDRRREFQLGESVKYFLDNLDKLGEPDYIPSQQDILLARRPTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVLMEDRLTNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQIVSIKDYFLEFEGDPHCLRDVQKFLVECFRNKRRDQQQKPLYHHFTTAINTENIRLVFRDVKDTILHDNLKQLMLQ
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems (PubMed:15240885, PubMed:16787920, PubMed:16705036, PubMed:27084452).  Activates effector molecule RhoA by binding and activating RhoGEFs (ARHGEF1/p115RhoGEF, ARHGEF11/PDZ-RhoGEF and ARHGEF12/LARG) (PubMed:15240885, PubMed:12515866).  GNA13-dependent Rho signaling subsequently regulates transcription factor AP-1 (activating protein-1) (By similarity).  Promotes tumor cell invasion and metastasis by activating RhoA/ROCK signaling pathway (PubMed:16787920, PubMed:16705036, PubMed:27084452).  Inhibits CDH1-mediated cell adhesion in process independent from Rho activation (PubMed:11976333).
What are the official names of this protein?
Guanine nucleotide-binding protein subunit alpha-13, G alpha-13, G-protein subunit alpha-13.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family. G(12) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Melanosome. Cytoplasm. Nucleus. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). Detected in the cytoplasm of Leydig cells and in the seminiferous epithelium, including differentiating cells from the spermatogonia to mature spermatozoa stages (PubMed:18703424). In round spermatids, also present in the nuclei (PubMed:18703424).
Protein: LEUC_ROSS1
Sequence: MTPRTLFDKVWDAHIVRPQTAETPAVIYIDLHLIHEVTSPQAFTELRQRGLKVRRPDRTLATMDHSTPTTPRGADGIIPVVDAQAAAQLRQLEQNCAEFGIPLFALGSEYQGIVHVIGPEQGLTQPGMTIVCGDSHTSTHGAFGALAFGIGTSEVAHVLATQCLIQTRPKTMEVRVDGRLAPGVTAKDIILAIIARYGVGAGTGHVFEYTGETIRALSMEERMTICNMSIEGGARAGMIAPDDTTFEYIAGRPFAPKGKAWDEAVAYWRTLPTDEGAVYDRIITLDASQLTPMITYGTNPGMGMPIDGRIPTPEELPDPAARQALDKALRYMDLRPGQPLLGHKIDVVFLGSCTNSRISDLRMAARLLKGRKIADGVRMMVVPGSQQVKKQAEAEGLHEIFRAAGAEWREAGCSACLGMNDDKVPPGRYAVSTSNRNFEGRQGPGARTFLASPLTAVASAIEGAVADPRRYLGG
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: THIC_NITEC
Sequence: MKIPVSRLEKFTSDNARVDTAAIQSLPNSRKIYIQGSRADIRVPMREISQSDTNTSQGIEKNPPICVYDTSGPYSDPDTNIDIRHGLLPLREKWIEEREDTEVLSGLSSSYSLKRLQDPALTAMRFNLTRPVRRAKGGSNVTQMHYARRGIITPEMEFIAIRENQRRERVTDLAKSELLTRQHPGQSFGAAIQEWITPEFVRDEVARGRAIIPANINHPEAEPMIIGRNFLVKINANIGNSALGSSIQDEVEKMTWAIRWGGDTVMDLSTGKNIHETREWIIRNSPVPIGTVPIYQALEKVDGKAEELTWEIFRDTLIEQAEQGVDYFTIHAGVRLPFVPMTAKRMTGIVSRGGSIMAKWCLAHHKESFLYTHFEDICEIMKAYDVSFSLGDGLRPGSIYDANDEAQFAELKTLGELTKIAWKHDIQTMIEGPGHVPMHLIRENMDLQLEHCHEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWYGTAMLCYVTPKEHLGLPDKDDVKDGIITYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWNDQFNLSLDPDKARQFHDETLPQEGAKLAHFCSMCGPNFCSMKITQDVRDYAAQQGISENEALQEGMAKKADEFIEKGGEIYRKL
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: RELH_RABIT
Sequence: MPALLFYLLGFCLLQGQVTGRVTYEWMMENVKICRNDFVRTAIEVCGHVHLERESPSPENPFLSSGPAAETVPSSIKKDAENANTMLESIPNLPQELTATLFEKQPSKLYLQYLPTLKKSNVSFEEFKKIIQNIQRGVQGSSASESNTFSRKKRQFSESLPEECCKYGCPRYYLLMYC
What are the official names of this protein?
Relaxin-like protein SQ10.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MSRA_SALCH
Sequence: MNLFDKKHLVTQADALPGRNTPMPIATLHAVNEHSMTNVPAGMEIAYFAMGCFWGVERLFWQLPGVYSTAAGYAGGYTPNPTYREVCSGQTGHAEAVRIVYDPAVIRYEQLLQTFWENHDPTQGMQQGNDHGTQYRSAIYPLTPEQNAAAHASRERFQSAMAAAGDHRPITTEIAHATPFYYAEDEHQQYLHKNPYGYCGIGGIGVCLPPDA
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.