PharMolix/UniProtQA huggingface dataset:
Protein: CHB4_ANTPO
Sequence: TKSILILPSALMIQSAVGQCLGRWGPGLGRCGGCGGCDGWGGRLGYGAGIGEIGLGCGLEASYGGGLGVASASAVPPVGLGVASENMYEGCVGVAGNLPFLGTAGVEGVFPTAGAGVINYGCGDGAVGITSEGGYGGLGYGGLGYEGVGGYGLGYGGYGLGGCGCGCGRYL
What is the function of this protein?
This protein is one of many from the eggshell of the silk moth.
What are the official names of this protein?
Chorion class B protein PC401.
What is the protein family that this protein belongs to?
Belongs to the chorion protein family.
Protein: PTI6_SOLLC
Sequence: MTENSVPVIKFTQHIVTTNKHVFSEHNEKSNSELQRVVRIILTDADATDSSDDEGRNTVRRVKRHVTEINLMPSTKSIGDRKRRSVSPDSDVTRRKKFRGVRQRPWGRWAAEIRDPTRGKRVWLGTYDTPEEAAVVYDKAAVKLKGPDAVTNFPVSTTAEVTVTVTETETESVADGGDKSENDVALSPTSVLCDNDFAPFDNLGFCEVDAFGFDVDSLFRLPDFAMTEKYYGDEFGEFDFDDFALEAR
What is the function of this protein?
Acts as a transcriptional activator.  Binds to the GCC-box pathogenesis-related promoter element.  Activates the defense genes of plants.
What are the official names of this protein?
Pathogenesis-related genes transcriptional activator PTI6, PTO-interacting protein 6.
What are the subcellular locations of this protein?
Nucleus.
Protein: STT4_YEAST
Sequence: MRFTRGLKASSSLRAKAIGRLTKLSTGAPNDQNSNGTTLDLITHTLPIFYSTNTSKIYTIPLTLSEWEVLTSLCVAIPTTLDLVETMLKEIIAPYFLETPRQRISDVLSSKFKLEQMRNPIELLTFQLTKFMIQACEQYPVLYENIGGIISTYFERVLKIFTIKQSGLLSLVGFINAFIQFPNSTELTKFTWKKLAKLVLRGSFLNEVDKILNSSATFTNDSIVQYYDAGNELSSAYLLELISRLQVSLISHLLNTSHVGANLSEFLLNQQYQFYKFDQEVADENDDTKCIDDFFFNVRSNKQFFTDMCKISLQFCSESHILDLSTDNRARFSFDTRAHYLQTLCLIPFIEDTESELFESFTNVVSESIDKFFLSDVVTPSLIKAIVASASLLNFFTEKLSLTLIRMFPLLVASPHITTETVNDVAKIFTTGLYPLNEDAIVSTIYSMNNLLAVSEDGSPVPVLRERQLTITSGKNIEKDYFPLRNSSASLDGTGALLGNTTVGQLSSHDVNSGATMTYHASLISNCVAATTTIASYYNTQSITALTISILTQKVNSMSKELDGVILNSLARLAPNTSLTEFSLLLKFFKSRTVIATKIDDSALLKNIIKAKCVISKELLARHFSSDLYFMYLHDLLDSIIASGEVERLEHHRPQTEISRVADQIATYLEPLAALLPVPGDTPLDINKDEVTTNKFRNAWFNFVIHGYHLGGPIVKRNFSFLLTIAYNSPPLASEFPANNKELSLEMNTILRRGSSNENIKQQKQQITEYFNTNIVQYRTTSSSKIMFLAAAVLLETIRCEAGDCSKTLLYFSDPSILSGSIEKCIAVLSVSMIRKYARLIQKGNDAIFNSKMIAQQLNNLLLCLSHREPTLQDAAFHACEIFIRSIPSSLCHHLSLYTLLDMLTALFDSILDSEAHKFEPRYEFKLKHSKTTILVPSSSSWRATTLSRLHKSAKEWVRILLNRSNQDTKILLQSYISDLGEYSRLNSVEFGVSFAMDMAGLILPADKELSRLTYYGPEKPNTISGFISLHSWRSKYLFDTAITSSPEDIKRQIGISTQNIRKNLTLGNKIITKDVTDFLDMATALLILGNGAPASLIYDIVHIPFEVFTSASLKIATNVWLTIITEKPEVAHLLLVEVCYCWMRSIDDNIGLYSRDHDLKGEEYQKMEYSPYDKAGINRDAKNASQAMQPHLHVIKFFASHFEGTLFQSDFLLKIFTKCALYGIKNLYKASLHPFARMIRHELLLFATLVLNASYKQGSKYMGRLSQEITNGALSWFKRPVAWPFGSNELKIKADLSVTRDLFLQLNKLSSLMSRHCGKDYKILNYFLASEIQQIQTWLTPTEKIEGADSNELTSDIVEATFAKDPTLAINLLQRCYSKKAEDVLVGLVAKHALMCVGSPSALDLFIKGSHLSSKKDLHATLYWAPVSPLKSINLFLPEWQGNSFILQFSIYSLESQDVNLAFFYVPQIVQCLRYDKTGYVERLILDTAKISVLFSHQIIWNMLANCYKDDEGIQEDEIKPTLDRIRERMVSSFSQSHRDFYEREFEFFDEVTGISGKLKPYIKKSKAEKKHKIDEEMSKIEVKPDVYLPSNPDGVVIDIDRKSGKPLQSHAKAPFMATFKIKKDVKDPLTGKNKEVEKWQAAIFKVGDDCRQDVLALQLISLFRTIWSSIGLDVYVFPYRVTATAPGCGVIDVLPNSVSRDMLGREAVNGLYEYFTSKFGNESTIEFQNARNNFVKSLAGYSVISYLLQFKDRHNGNIMYDDQGHCLHIDFGFIFDIVPGGIKFEAVPFKLTKEMVKVMGGSPQTPAYLDFEELCIKAYLAARPHVEAIIECVNPMLGSGLPCFKGHKTIRNLRARFQPQKTDHEAALYMKALIRKSYESIFTKGYDEFQRLTNGIPY
What is the function of this protein?
Acts on phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol 1,4,5,-trisphosphate.  STT4 functions in PKC1 protein kinase pathway.
What are the official names of this protein?
Phosphatidylinositol 4-kinase STT4, PI4-kinase, PtdIns-4-kinase.
What is the protein family that this protein belongs to?
Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
Protein: ATPA_STRPQ
Sequence: MAINAQEISALIKKQIENFQPNFDVTETGIVTYIGDGIARARGLDNAMSGELLEFENGAYGMAQNLESNDVGIIILGDFSAIREGDVVKRTGKIMEVPVGEALIGRVVNPLGQPVDGLGDIETTGFRPVETPAPGVMQRKSVSEPLQTGLKAIDALVPIGRGQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRRYGALDYTIVVTASASQPSPLLFIAPYAGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLLLRRPPGREAYPGDVFYLHSRLLERSAKVSDDLGGGSITALPFIETQAGDISAYIATNVISITDGQIFLQENLFNSGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRLDLASYRELEAFTQFGSDLDAATQAKLNRGRRTVEILKQPLHKPLPVEKQVVILYALTHGFLDDVPVDDILAFEEALYDYFDVHYNDLFETIRTTKDLPEEAALDAAIKAFKEHSNFKS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: DGTL1_CLOTE
Sequence: MSIDKMSLRKRVENIERISIIPEGTKSEDTKGRIIKENQDDIRTVFMVDRDRIIHSKSFRRLKHKTQVYIKTWGDHYRTRLTHTLEVAQIGKTIGKSIGLNEDLIEAIALGHDIGHVAFAHSGEEVLNELLPNGFKHNINSIRVLTKIEKQGKGLNLTKEVLDGILHHSGFSNKKDITKAFTLEGQVVKYSDKIAYVNHDIDDSIRAGLLHESDLPKDLINVLGRNHSDRIDTLVKDCINKTLENIKLGTIEVGMSEKIEIALKELRKFMFQRVYKGSILKEERDKAKFVLYQVFNYYLKNSNKMPEFYKNIVEQEGLYQGVADYISGMSDDYCLLLFNNIYVPKIVIY
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 2 subfamily.
Protein: PICK1_RAT
Sequence: MFADLDYDIEEDKLGIPTVPGKVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEVTIHYNKLQADPKQGMSLDIVLKKVKHRLVENMSSGTADALGLSRAILCNDGLVKRLEELERTAELYKGMTEHTKNLLRAFYELSQTHRAFGDVFSVIGVREPQPAASEAFVKFADAHRSIEKFGIRLLKTIKPMLTDLNTYLNKAIPDTRLTIKKYLDVKFEYLSYCLKVKEMDDEEYSCIALGEPLYRVSTGNYEYRLILRCRQEARARFSQMRKDVLEKMELLDQKHVQDIVFQLQRFVSTMSKYYNDCYAVLRDADVFPIEVDLAHTTLAYGPNQGGFTDGEDEEEEEEDGAAREVSKDARGATGPTDKGGSWCDS
What is the function of this protein?
Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence.  Involved in the clustering of various receptors, possibly by acting at the receptor internalization level.  Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors.  May be regulated upon PRKCA activation.  May regulate ASIC1/ASIC3 channel.  Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competitive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis.  Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD).  Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function.
What are the official names of this protein?
PRKCA-binding protein, Protein interacting with C kinase 1, Protein kinase C-alpha-binding protein.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Membrane; Peripheral membrane protein. Membrane; Lipid-anchor. Postsynaptic density. Synapse, synaptosome. Cytoplasm, cytoskeleton. Note=Also membrane-associated, present at excitatory synapses.
Protein: GATA_CERSK
Sequence: MNANELTIAEARDALAKGELSAVDLTMACLTAIDAGTPLNAFVHATPEIALDQARAADARRGAEAGALNGIPLGIKDLFCTRGVASQAASNILRGFKPEYESTVTSKLFEAGAVMLGKLNMDEFAMGSSNETSCYGDAVNPWKVDDRRLTPGGSSGGSAAAVAADLCLAATGTDTGGSIRQPAAFTGIVGIKPTYGRVSRWGIVAFASSLDQAGPMTKSVRDAAILLGAMAGHDPKDSTSADIPVPDFEAALTGDIRGRKIGIPREYRMEGMPAEIEALWARGREMLADAGAEIVDISLPHTKYALPAYYVIAPAEASSNLARYDGVRYGHRARLGQGDGIVDMYEKTRAEGFGKEVQRRVMIGTYVLSAGFYDAYYNRARKVRALIKRDFDEAFAAGVDAILTPATPSSAFGLGEMADADPVAMYLNDVFTVTVNLAGLPGISVPVGLDAKGLPLGLQLIGRPWDEAGLLNHAHVLERAAGFVEKPRKWW
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: RLMN_FRATM
Sequence: MQQDKVNLLGLNQKAIEDFFISIGEKKFHARQVFKWIHKKGVIDFDAMTDLGKNLRHKLKEKAQITIPKVVFSKASKDGTHKWLIDVGGSAVETVFIPEEGRGTLCVSSQVGCTLNCSFCSTGKQGFNRNLSAAEVIAQLWIAARTLSKTDGEHDFTVTNIVMMGMGEPLMNFENVVPAMDIMMDDLAYGLSRRKVTLSTSGVVPRIYDLLEQSGVSLAVSLHAPNDMLRNEIVPINKKYNIDELLEACKLYAQNGPHKHITFEYTLMEEVNDNLSDAEELVALLKSREVPAKINLIPFNPYPGTPYKKPSNNRIHRFKEFLQHNGFVTTVRKTRGDDIDAACGQLAGDVMDKTNRKQRYLKKLGDTNAN
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_MANSM
Sequence: MGQKVNPHGIRLGIVKPWSSTWFANTQDFASNLDGDFKVRKFLNKELANASVSRITIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRNAVAKIAGVPAQINIAEVKKPELDAKLVADSIASQLERRVMFRRAMKRAVQNAMRLGAKGIKVEVSGRLGGAEIARSEWYREGRVPLHTLRADIDYNTSEAHTTYGVIGVKVWIFKGEILGGMAAIAQQPEQQPAAPKKAPRGKGRK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: GCST_ECOSM
Sequence: MAQQTPLYEQHTLCGARMVDFHGWMMPLHYGSQIDEHHAVRTDAGMFDVSHMTIVDLRGSRTREFLRYLLANDVAKLTKSGKALYSGMLNASGGVIDDLIVYYFTEDFFRLVVNSATREKDLSWITQHAEPFGIEITVRDDLSMIAVQGPNAQAKAATLFNDAQRQAVEGMKPFFGVQAGDLFIATTGYTGEAGYEIALPNEKAADFWRALVEAGVKPCGLGARDTLRLEAGMNLYGQEMDETISPLAANMGWTIAWEPADRDFIGREALEAQREHGTEKLVGLVMTEKGVLRNELPVRFTDAQGNQHEGIITSGTFSPTLGYSIALARVPEGIGETAIVQIRNREMPVKVTKPVFVRNGKAVA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: SYK_PSEU2
Sequence: MSDQQLDPQALQQEENTLIALRKEKLAAGRAKGQAFPNDFRRDSYCNDLQKQYVDKTKEELAEAAIPVKVAGRIMLNRGSFMVIQDMTGRIQVYVNRKTLPEETLAEVKTWDLGDIIAAEGTLARSGKGDLYVEMTSVRLLTKSLRPLPDKHHGLTDTEQRYRQRYVDLIVNEEVRETFRVRSQVIAHIRSFLMKRDFLEVETPMLQTIPGGAAAKPFETHHNALDMEMFLRIAPELYLKRLVVGGFEKVFEINRNFRNEGVSTRHNPEFTMLEFYQAYADYEDNMDLTEELFRELAQLVLGSTDVPYGDKVFHFGEPFVRLSVFDSILKYNPELTVADLQDIDKARAIAKKAGAKVLGFEGLGKLQVMIFEELVEHKLEQPHFITQYPFEVSPLARRNDENPNVTDRFELFIGGREIANAYSELNDAEDQAERFQAQVADKDAGDDEAMHYDADFVRALEYGMPPTAGEGIGIDRLVMLLTDSPSIRDVILFPHMRPQA
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE1_SINMW
Sequence: MSYKMSRAAYANMFGPTVGDKVRLADTELFIEVERDFTTHGEEVKFGGGKVIRDGMGQSQVTREGGAVDTVITNALIVDHWGIVKADIGLKDGRISAIGKAGNPDTQAGVTIIVGPGTEVIAGEGKIVTAGGMDSHIHFICPQQIDEALMSGITCMLGGGTGPAHGTLATTCTPGPWHIARMIEAADAFPMNLAFAGKGNASLPGALVEMVLGGATSLKLHEDWGTTPAAIDCCLSVADEYDVQVMIHTDTLNESGFVEDTIAAIKGRTIHAYHTEGAGGGHAPDIIRICGQPNVIPSSTNPTRPYTVNTLAEHLDMLMVCHHLSPSIPEDIAFAESRIRKETIAAEDILHDIGAFSIISSDSQAMGRVGEVAIRTWQTADKMKRQRGRLKEESGGNDNFRVKRYIAKYTINPAIAHGLSHEIGSLETGKRADLVLWNPTFFGVKPDMVLLGGTIAAAPMGDPNASIPTPQPVHYRPMFGAYGKSRTNSSVTFVSQASLDAGLAGRLGVAKALVAVQNTRGGIGKASMVHNSLTPHIEVDPETYEVRANGELLTCEPASVLPMAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAI_CARCL
Sequence: MTTINFPSLFVPLVGLIFPAIAMASLFLYVQKNKIV
What is the function of this protein?
May help in the organization of the PsaL subunit.
What are the official names of this protein?
Photosystem I reaction center subunit VIII, PSI-I.
What is the protein family that this protein belongs to?
Belongs to the PsaI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: PGA4_CANAL
Sequence: MLFRSLVTYLSLVSSVLSIASIKVEGNAFWDSESGDRFYIRGVDYQPGGSSELEDPLADTNVCERDVKYFQELGINTIRVYSIDNTKNHTECMDTLAKAGIYVILDVNTPHSSITRSDAACSYNTDYLQEVFASIVEFAQFDNTLGFFAGNEVINDGPSLEAAPYVKAVVRDMKTFIKNRGFRTIPVGYSAASVDEYRLPSGLYFNCGDDDMARIDMYGINDYSWCGDASMTTSQYSQQMKDFANYTVPLFFSEFGCNAKRPRPFSEIEAIYSTEMSSVFSGGLVYEYSEEASNYGLVELKGDSVTTNDDFDNLKSQFEKTKNPSGDGGYLKSTGGNKCPPKSNIWNVTEEIPDTPKGALKYLKGLAEPTGHGFDAYVQGNCNAKGNNVDDTGNYTSSITASSRASPSQTSQVSSSSATSANSTSSKKNDAAVEGAGFLSVIALAAGIALL
What is the function of this protein?
Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.  Involved in cell wall biosynthesis and morphogenesis.  Plays a key role in virulence.
What are the official names of this protein?
1,3-beta-glucanosyltransferase PGA4, GPI-anchored protein 4.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 72 family.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor. Note=Covalently-linked GPI-modified cell wall protein (GPI-CWP).
Protein: LSRK_YERPB
Sequence: MSQLDTTTPSGDYLMALDAGTGSVRAVIFDLNGNQIAAGQAEWLHLPVPDVPGSMEFDLTTNWQLTCQCIRQALHLAKLPASAIRAVAACSMREGIVLYDRSGTPIWACANVDARASREVSELKELHNNGFELEVYQCSGQTLALSAMPRLLWLAHYRPDIYRQAGTLTMISDWLANMLSGELAVDPSNAGTTGMLDLVTRNWQPNLLEMAGLRADILSPVKETGTLLGHVTAKAAQECGLLAGTPVVMGGGDVQLGCLGLGVVHAGQTAVLGGTFWQQVVNLPQPIIDPNMNTRINPHVIPGMVQAESISFFTGLTMRWFRDAFCAEEKLLAQRLGIDTYSLLEDMAARVPAGAYGVMPIFSDVMRFKSWYHAAPSFINLSLDPEKCNKATLFRALEENAAIVSACNLAQIAEFSGVKASSVVFAGGGAKGKLWSQILADVTGVPVKVPVVKEATALGCAIAAGVGVGLYEALDKTGERLVRWEREYIPNTEHKALYQAAKTNWQAVYTDQLGLVDCGLTTSLWKAPGL
What is the function of this protein?
Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon.  Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position.
What are the official names of this protein?
Autoinducer-2 kinase, AI-2 kinase.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABH_GRATL
Sequence: MQGAQIISIGSAVPDLCINNKEISQIVETSDEWIVTRTGIQERRVLTGTNKSVVDLAYSAAMKALDKIHMDPLEIDLIILATSSPNDLFGSASQVQAKIGAARAVAFDLTAACSGFVLAIVTATQFIQNGSYKNILIIGADVLSKWIDWSDRKTCILFGDGAGAAIIQACYEEDNAILGFQLNTDGKQYKKLSITYKENNYSLNTLKLFQGQFQYISMNGKEVYKFAVSKVPASIIKCLNALHLSIQDVNWLLLHQANKRILQAVANRLSVDNYKIISNLSKYGNTSAASIPLALDEAWQNNQIAKEDIIVISGFGAGLTWGTVVIKWKC
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ST_POVLY
Sequence: MDQTLSKEERNELMDLLQITRAAWGNLSMMKKAYKNVSKLYHPDKGGDSAKMQRLNELFQRVQVTLMEIRSQCGSSSSQVAWFFWDENFRTLGAFLGEKFNEKIIGLYPTCTKFVRANCNCIVCLLKKQHAGTKKNLKKPCLVWGECWCYKCYLVWFGFPEDFTSFRYWTLLMANMDLSMLKLWTELGF
What is the function of this protein?
Promotes efficient viral genome replication by accelerating both G1 and S phase progression of the cell cycle.  Inhibits host PP2A by binding to the A subunit, thereby displacing lower affinity regulatory B subunit.  Inactivation of PP2A in turn results in the transactivation of cyclin A and cyclin D1 promoters.  Late during the infection cycle, ST may induce dephosphorylation of host MTOR, leading to the inhibition of cap-dependent translation.  May establish and maintain high levels of viral genomes during persistent infection in cell culture.
What are the official names of this protein?
Small t antigen, ST, ST-AG.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: RL24_BURVG
Sequence: MNKIRKGDEVIVVTGKDKGKRGVVLAVGAEHVTVEGINLVKKHVKPNPMKGTTGGVEAKTMPLHISNVALVDANGKASRVGIKVEEGKKVRFLKTTGAVLSA
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: SARM1_PIG
Sequence: MVLTILFSAYKLCRFFAMSSPRPGAERLAVPGPDGGGGAGPWWTAGGRGPREVSPGVGAEVQGALERALPELQQALSALKQAGGGRAVGAGLAEVFQLVEEAWLLPAMGREVAQGLCDAIRLEGGLDLLLRLLQAPELETRVQAARLLEQILVAENRRDRVARIGLGVILNLAKEREPVELARSVAGILEHMFKHSEETCQRLVAAGGLDAVLYWCRRTDPALLRHCALALANCAMHGGQAAQRRMVEKRAAEWLFPLAFSKEDELLRLHACLAVAVLATNKEVEREVERSGTLALVEPLVASLDPGRFARCLVDASDTSQGRGPDDLQRLVPLLDSSRMEAQCIGAFYLCAEAVIMHIKNRNKVFSDIGAIQSLKRLVSYSTNGTTSALAKRALRLLGEEVPRPILPCVASWKEAEVQTWLQQIGFSQYCESFREQQVDGDLLLRLTEEELQTDLGMKSGITRKRFFRELTELKTFANYATCDRSNLADWLGSLDPRFRQYTYGLVSCGLDRSLLHRVSEQQLLEDCGIRLGVHRVRILTAAREMLHSPLPCTGSKPSGDVPDVFISYRRNSGSQLASLLKVHLQLHGFSVFIDVEKLEAGKFEDKLIQSIMSARNFVLVLSAGALDKCMQDHDCKDWVHKEIVTALSCGKNIVPVIDGFEWPEPHTLPEDMQAVLTFNGIKWSHEYQEATIEKIIRFLQGRSSRDSSAGSDTSLEGAAPMGPT
What is the function of this protein?
NAD(+) hydrolase, which plays a key role in axonal degeneration following injury by regulating NAD(+) metabolism (By similarity).  Acts as a negative regulator of MYD88- and TRIF-dependent toll-like receptor signaling pathway by promoting Wallerian degeneration, an injury-induced form of programmed subcellular death which involves degeneration of an axon distal to the injury site (PubMed:22366489).  Wallerian degeneration is triggered by NAD(+) depletion: in response to injury, SARM1 is activated and catalyzes cleavage of NAD(+) into ADP-D-ribose (ADPR), cyclic ADPR (cADPR) and nicotinamide; NAD(+) cleavage promoting cytoskeletal degradation and axon destruction (By similarity).  Also able to hydrolyze NADP(+), but not other NAD(+)-related molecules (By similarity).  Can activate neuronal cell death in response to stress (By similarity).  Regulates dendritic arborization through the MAPK4-JNK pathway (By similarity).  Involved in innate immune response: inhibits both TICAM1/TRIF- and MYD88-dependent activation of JUN/AP-1, TRIF-dependent activation of NF-kappa-B and IRF3, and the phosphorylation of MAPK14/p38 (By similarity).
What are the official names of this protein?
NAD(+) hydrolase SARM1, NADase SARM1, NADP(+) hydrolase SARM1, Sterile alpha and TIR motif-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the SARM1 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, axon. Cell projection, dendrite. Synapse. Mitochondrion. Note=Associated with microtubules.
Protein: SUB3_ARTOC
Sequence: MGCIKVISVFLAAVAAVDARAFFHNRGGNDVIPNSYIVVMKDGVTAEDFDSHISSVATTHSINKAKRGSETVGHKDSFNINGWRAYNGHFDEATIESILNDDKVDYVEHDRVVKLAALTTQPNAPTWGLGRVSHKAPGNKDFVYDSSAGQGVTIYGVDTGIDINHPEFRGRIRWGTNTVDNDNTDGNGHGTHTAGTFAGTTYGVAKKANIVAVKVLSAGGSGSTAGVIKGIDWCVTDAKAKGALGKAALNLSLGGAFSQANNDAVTRAQNAGIFVAVAAGNDNKDAKNSSPASAPAVCTAASSTIDDQKSSFSNWGTIVDIYAPGSNILSAAPGGGTRTLSGTSMASPHVCGVGAAMLAQGVSVAQACDRIKQIANAVIKNPGTGTTNKLLYNGSGR
What is the function of this protein?
Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity.
What are the official names of this protein?
Subtilisin-like protease 3.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: AROA_CLOTE
Sequence: MHKEETFNQCALTINGYKSEVKKTYELPGDKSVGHRSLLIGALPKGEYKIRNFPQSRDCLTTLKIMEELGVKVKVLKDYILVNSPGYENFKKKIDYIDCGNSGTTSRLIAGILAGVGVETNLVGDKSLSIRPMKRIVDPLNSMGANIEMEKDHMPLIFKGNGELKGIDYTMEIASAQVKSCILLAGFLSEGVTKVRELSPTRDHTERMLKYIEGNIKIENKEIEIENSTIKSKDIYVPGDISSAAYIIACAILGEDCEIILENVLLNENRRKYLDLLKKMGANLKYLEKNQCNGEHVGNILVKSSFLKGISIGKEITPYIIDEIPIISLIASFAEGKTIFENVEELKYKESDRIKAIMVNLKSLGVKTELVENNLIIYGGLSKINKEINIRTFNDHRIALTFLCSAMRNSEKTYIDNWDCVAISFPNSLNYFKDFFRIN
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE1_HYPNA
Sequence: MSVVTRFAPSPTGMLHIGGARTALFNYLFARRNGGRFLLRIEDTDRERSTQEATDAILDAMEWLGLTPDEPPVMQSAQVDRHAAVAHDMVARGTAFRCYVTPEELQARRDLGEEKRQAAKQEGISDAEKEALLAEASQLLAPFRSPYRDGASPPSPDAPFTVRLRAPESGPRTVEDGVQGTVTIDASEIDDLVMLRADGTPTYMLAVVVDDHDMGITHVIRGDDHLRNTFRQVPIYEAMGWSVPNFSHVPMIHGNDGAKLSKRHGALSTTAYRDMGYLPEAMKAYLLRLGWSHGDQEIFTDEEAVQVFDVSGINKAPARLDLDKLATVNAHFMRLAADERLFDLICPVLSKNCSLSDAEVARIRAALPHMKDRGSTLIELANAFAFLYAKRPLELNKNAVKALSDEGKLRLKGLYDDLQRMSQWSGASISETIKSYCAATGLSMGQIGPPLRAALTGGLPAPDLAPVMDWLGREETLARIDDQLAG
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 1, Glutamyl-tRNA synthetase 1, GluRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2610_EDWI9
Sequence: MPQSSRYSDQRVEQLLSELVNVLESQHAPTDLSLMVLGNMVTNLINTSVAPTQRSMIARSFADALQASIREDKAH
What are the official names of this protein?
UPF0352 protein NT01EI_2610.
What is the protein family that this protein belongs to?
Belongs to the UPF0352 family.
Protein: CDX1_XENLA
Sequence: MYVGYLLDKDNNMYPNPVRHPGLNLNPQNYVPAPPQYSDFPSYHHVPGINSDPHHGQPGGTWSSYTPSREDWHPYGPGPGASSANPTQIAFSPSDYNPVQPPGSGLLPPSINSSVPPLSPSAQRADPYEWMRRTGVPTTTTTTNGKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAAALGLTERQVKIWFQNRRAKERKVNKKKMQQQSQQASTTTPTPPSVGTTAGMGGLCSSSSSNSNLVSPSSMPIKEEYLS
What is the function of this protein?
Plays a role in transcriptional regulation.  Involved in activated KRAS-mediated transcriptional activation of PRKD1.  Binds to the PRKD1 promoter.  Could play a role in the terminal differentiation of the intestine.  Binds preferentially to methylated DNA.
What are the official names of this protein?
Homeobox protein CDX-1, xCAD2.
What is the protein family that this protein belongs to?
Belongs to the Caudal homeobox family.
What are the subcellular locations of this protein?
Nucleus.