PharMolix/UniProtQA huggingface dataset:
Protein: OTC_SCHPO
Sequence: MSFKKFPRHLLSIRDLSRGEIVKLIDRSSEIKQAYKQNFQNRRSVQMSGLSSQNVAMIFSKRSTRTRVSVESAVSCLGGNAMFLGKDDIQLGVNESLYDTSKVISSMVSGIVARVNKYSDVATLAKHASCPVINGLCDTFHPLQALADLLTIKETFKSFDGLKVAWVGDANNVLHDLMIANAKVGIHTSVAKPKDVNVRDDILSIVNEAANENGSTFEIVNDPKVAVKNADIVVTDTWISMGQEAEKEQRLKQFTGFQVTGEIMKLAKPSCKFMHCLPRHPEEVSDEVFYGENSLVFQEAENRKWTTVAVLEALLVNRGEILPPASA
What is the function of this protein?
Ornithine carbamoyltransferase involved in the synthesis of arginine from glutamate via ornithine and the urea cycle.
What are the official names of this protein?
Ornithine carbamoyltransferase, mitochondrial, Ornithine transcarbamylase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RS16_PSEPK
Sequence: MVTIRLARGGSKKRPFYHLTVTNSRNARDGRFVERVGFFNPIAAGAEVKLSVNQERVTYWLSQGAQPSERVAQLLKEAAKAAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: HBA_GORGO
Sequence: VLSPADKTNVKAAWGKVGAHAGDYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR
What is the function of this protein?
Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1.  Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.
What are the official names of this protein?
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: SYD_SALAR
Sequence: MRTEYCGQLRLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGIVQVFFDPDRADALKLASELRNEFCIQVTGTVRARDAKNVNADMATGEIEVLASSLTIINRADSLPLDANHINTEEARLKYRYLDLRRPEMAQRLKTRAKITSLVRRFMDDHGFLDIETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDVETSFMTAPQVREVMEALVRHLWLEVKDVDLGDFPVMTFAEAERRYGSDKPDLRNPMELVDVADLLKSVEFAVFAGPANDPKGRVAALRVPGGAQLSRKQIDDYGNFVKIYGAKGLAYIKVNDRAKGLDGITSPVAKFLSTEIVEAILARTGAQNGDMIFFGADNKKVVADALGALRLKLGKDLSLTDEDKWAPLWVIDFPMFEDDGEGGLTAMHHPFTAPRDMTASELKAAPENAVANAYDMVINGYEVGGGSVRIHNGEMQQTVFGILGINEQEQREKFGFLLDALKYGTPPHAGLAFGLDRLTMLLTGTDNIRDVIAFPKTTAAACLMTEAPSFANQAALTELGIQVVKKAENN
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGB_STAAB
Sequence: MKFIVIKIGGSTLSDMHPSIINNIKHLRSNNIYPIIVHGGGPFINEALSNQQIEPHFVNGLRVTDKATMTITKHTLIADVNTALVAQFNQHQCSAIGLCGLDAQLFEIKRFDQQYGYVGVPTTLNIDSLSYLCTKFVPIINSIGFNNHDGEFYNINADTLAYFIAASLEAPIYVLSNIAGVLINDVVIPQLPLADINQYIEHGDIYGGMIPKVLDAKNAIENGCPKVIIASGNKPNIIEAIYNNDFVGTTILKSLV
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IPI1_CHATD
Sequence: MGSSSKKKKEKQKDFQKPKLKVGKPKQKPSNFTDTSFKTKSIVVNQQTLTTEGLDSAELFKQNLTLAVNAKSDNQRRDALAYVTNQLSANPANNPVGTVGVLTKVLPLITDGASSVRVQLLKLFRTLPPQEVRPHAEKILLYIRGGMTHLSNDVRTDTLNVLDWLLEVAGDEVVSCPGGWLKTLNSFSSMLGWNPNVSSAMTTKGWTSAPKATLGMKKGPESQAKQIQVLAKFLQTGFRPEEPLPYKPRAYWDNIYRLPTTPNPFAYLNLFGLPRDEDSEMYPDRMSRLRVFDMKWRAAITSGMETAKKEGGTVGRAAAILDKALKASLESDGSMQVN
What is the function of this protein?
Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
What are the official names of this protein?
Pre-rRNA-processing protein IPI1.
What is the protein family that this protein belongs to?
Belongs to the IPI1/TEX10 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NFUA_KLEP3
Sequence: MIRISDAAQAHFAKLLANQEEGTQIRVFVINPGTPNAECGVSYCPPDAVEDTDTALKFEQLTAYVDELSAPYLEDAEIDFVTDQLGSQLTLKAPNAKMRKVSDDAPLMERVEYLLQSQINPQLAGHGGRVSLMEITDDGLAILQFGGGCNGCSMVDVTLKEGIEKQLLNEFPELKGVRDLTEHQRGEHSYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: YH32A_YEAST
Sequence: MKLLQGRMTYRGDAHPHPRITPSLLANYVGNFKGFAMWHATGKIIHVPVRHQTGMHFCI
What are the official names of this protein?
Uncharacterized protein YHR032W-A.
Protein: MPTA_METMA
Sequence: MEKCTFNLPDVQASKPSIAINLTRVGVTNMKKLVEIKRKDKRPIVLISTFDVFVDLPSDRKGANLSRNFEAVDEVLEKVLSTPVYEIEQLCSDIAHNLLGRHEYANQAEVRMKSEYMIRRASPSTGIKCQEVVNIFAEASAVRGNGDRDYFDVKKLIGAEVVGMTACPCAQEIMRDKAATELANLGVERDKIIKFLEKVPMATHNQRGRGIISIKVAHDFDVSLESIIKIIERSMSSSVYEVLKRSDEKVVVETAHMNPKFVEDCVRAMADNVVKEFPNLPDNAVITIKQTNEESIHRHNAFAERVALMGELRKEISQ
What is the function of this protein?
Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
What are the official names of this protein?
GTP cyclohydrolase MptA, GTP cyclohydrolase IV.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: TRBP2_HUMAN
Sequence: MSEEEQGSGTTTGCGLPSIEQMLAANPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVPLDARDGNEVEPDDDHFSIGVGSRLDGLRNRGPGCTWDSLRNSVGEKILSLRSCSLGSLGALGPACCRVLSELSEEQAFHVSYLDIEELSLSGLCQCLVELSTQPATVCHGSATTREAARGEAARRALQYLKIMAGSK
What is the function of this protein?
(Microbial infection) Binds to the HIV-1 TAR RNA which is located in the long terminal repeat (LTR) of HIV-1, and stimulates translation of TAR-containing RNAs (PubMed:2011739, PubMed:11438532, PubMed:12475984).  This is achieved in part at least by binding to and inhibiting EIF2AK2/PKR, thereby reducing phosphorylation and inhibition of EIF2S1/eIF-2-alpha (PubMed:11438532).  May also promote translation of TAR-containing RNAs independently of EIF2AK2/PKR (PubMed:12475984).  Mediates recruitment of FTSJ3 methyltransferase to HIV-1 RNA, leading to 2'-O-methylation of the viral genome, allowing HIV-1 to escape the innate immune system (PubMed:30626973).
What are the official names of this protein?
RISC-loading complex subunit TARBP2, TAR RNA-binding protein 2, Trans-activation-responsive RNA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the TARBP2 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Nucleus.
Protein: CENPN_CHICK
Sequence: MDEVIVEYIRRTVLKIPRDEIMAVLQKWGFLSEAQLQTINFRQTKEGISHSVAQLCEESSADLKQAALLDIIYNHIYPNKRVWSVYHMNKTGEETDFFDFRDFKKKFRRQIQSALINVTINFREYEDNAIWIRIAWGTPYTKPNQYKTSYVVYHSQTPYVFISASVLRSNLPLLCQAMVVASNYHDIHEMELRSHCLNSLKDIVFKRYSQNFQTNYPLQERNVLTENVDLRINDENRSEKERIYRLNQESFGNGPQPKLDFAQYKLETMFKSDPKWDVLEKKEPFRCLVKFSSPHLLESLKSLAPAGLADAPLSPLLTCIPQKARNYFKIREKKSLHPGSFVSP
What is the function of this protein?
Probable component of a centromeric complex involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation.
What are the official names of this protein?
Centromere protein N, CENP-N.
What is the protein family that this protein belongs to?
Belongs to the CENP-N/CHL4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Note=Localizes exclusively in the centromeres.
Protein: ATF7_PONAB
Sequence: MGDDRPFVCNAPGCGQRFTNEDHLAVHKHKHEMTLKFGPARTDSVIIADQTPTPTRFLKNCEEVGLFNELASSFEHEFKKAADEDEKKAAAGPLDMSLPSTPDIKIKEEEPVEVDSSPPDSPASSPCSPPLKEKEVTPKPVLISTPTPTIVRPGSLPLHLGYDPLHPTLPSPTSVITQAPPSNRQMGSPTGSLPLVMHLANGQTMPVLPGPPVQMPSVISLARPVSMVPNIPGIPGPPVNSSGSISPSGHPIPSEAKMRLKATLTHQVSSINGGCGMVVGSASTMVTARPEQSQILIQHPDAPSPAQPQVSPAQPTPSTGGRRRRTVDEDPDERRQRFLERNRAAASRCRQKRKLWVSSLEKKAEELTSQNIQLSNEVTLLRNEVAQLKQLLLAHKDCPVTALQKKTQGYLESPKESSEPTGSPAPVIQHSSATAPSNGLSVRSAAEAVATSVLTQMASQRTELSMPIQSHVIMTPQSQSAGR
What is the function of this protein?
Stress-responsive chromatin regulator that plays a role in various biological processes including innate immunological memory, adipocyte differentiation or telomerase regulation (By similarity).  In absence of stress, contributes to the formation of heterochromatin and heterochromatin-like structure by recruiting histone H3K9 tri- and di-methyltransferases thus silencing the transcription of target genes such as STAT1 in adipocytes, or genes involved in innate immunity in macrophages and adipocytes.  Stress induces ATF7 phosphorylation that disrupts interactions with histone methyltransferase and enhances the association with coactivators containing histone acetyltransferase and/or histone demethylase, leading to disruption of the heterochromatin-like structure and subsequently transcriptional activation (By similarity).  In response to TNF-alpha, which is induced by various stresses, phosphorylated ATF7 and telomerase are released from telomeres leading to telomere shortening (By similarity).  Plays also a role in maintaining epithelial regenerative capacity and protecting against cell death during intestinal epithelial damage and repair (By similarity).
What are the official names of this protein?
Cyclic AMP-dependent transcription factor ATF-7, cAMP-dependent transcription factor ATF-7, Activating transcription factor 7, Transcription factor ATF-A.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleoplasm. Chromosome, telomere. Note=Mainly nucleoplasmic. Restricted distribution to the perinuculear region. The sumoylated form locates to the nuclear peiphery.
Protein: Y1516_STAAE
Sequence: MTEHNHDSQLEINNEEELLTLFDEEGNEVLYRKVLEFYHPEFKKEYVILAEEGAQSDEDDMIELVPMINEPDESGDGGKLVPIETDEEWDMIEEVVNTEMEE
What are the official names of this protein?
UPF0473 protein NWMN_1516.
What is the protein family that this protein belongs to?
Belongs to the UPF0473 family.
Protein: EGFR_CHICK
Sequence: MGVRSPLSASGPRGAAVLVLLLLGVALCSAVEEKKVCQGTNNKLTQLGHVEDHFTSLQRMYNNCEVVLSNLEITYVEHNRDLTFLKTIQEVAGYVLIALNMVDVIPLENLQIIRGNVLYDNSFALAVLSNYHMNKTQGLRELPMKRLSEILNGGVKISNNPKLCNMDTVLWNDIIDTSRKPLTVLDFASNLSSCPKCHPNCTEDHCWGAGEQNCQTLTKVICAQQCSGRCRGKVPSDCCHNQCAAGCTGPRESDCLACRKFRDDATCKDTCPPLVLYNPTTYQMDVNPEGKYSFGATCVRECPHNYVVTDHGSCVRSCNTDTYEVEENGVRKCKKCDGLCSKVCNGIGIGELKGILSINATNIDSFKNCTKINGDVSILPVAFLGDAFTKTLPLDPKKLDVFRTVKEISGFLLIQAWPDNATDLYAFENLEIIRGRTKQHGQYSLAVVNLKIQSLGLRSLKEISDGDIAIMKNKNLCYADTMNWRSLFATQSQKTKIIQNRNKNDCTADRHVCDPLCSDVGCWGPGPFHCFSCRFFSRQKECVKQCNILQGEPREFERDSKCLPCHSECLVQNSTAYNTTCSGPGPDHCMKCAHFIDGPHCVKACPAGVLGENDTLVWKYADANAVCQLCHPNCTRGCKGPGLEGCPNGSKTPSIAAGVVGGLLCLVVVGLGIGLYLRRRHIVRKRTLRRLLQERELVEPLTP
What is the function of this protein?
Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:3260329).  Known ligands include EGF and TGFA/TGF-alpha (PubMed:3260329).  Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues (By similarity).  The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades (By similarity).  Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules (By similarity).  May also activate the NF-kappa-B signaling cascade (By similarity).
What are the official names of this protein?
Epidermal growth factor receptor, CER.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Nucleus membrane; Single-pass type I membrane protein. Endosome. Endosome membrane. Nucleus. Note=In response to EGF, translocated from the cell membrane to the nucleus via Golgi and ER. Endocytosed upon activation by ligand (By similarity).
Protein: PLSY_AGRFC
Sequence: MSALTDWQTAPALLALAALIGYLLGSIPFGLILTRMAGLGDVRKIGSGNIGATNVLRTGNKKLAAATLLLDALKGTAAVLVANALWGYEASLVAGFFAFLGHLFPVWLGFKGGKGVAVYIGVLLGAAPLMMLAFALIWLATAFITRYSSLSALLAMLIIPVALWVLGPEKTAMLVTLLSVISWWKHRENIRRLMAGTESRIGQKG
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL16_RICAE
Sequence: MLAPKKQKFRKAHKGRVASIAKAGTTLAFGSFGLKSIDGWRVTARQIEAGRKAATRCMKRQGRLWIRIFPDVPVSKKPAEVRMGKGKGSPEFFAVRVSPGRIMFEIEGVEENVALRALELVSAKLPVRTRIVRRYE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: SEY1_PICGU
Sequence: MSDLPPPDLGSEEISVSPTSSSSSFVPIDKNQLQDAVQVVSEAKEFNSLILDYVRKATPASEVNNNYHIVSVFGSQSTGKSTLLNRLFNTNFDVMDESNRSQTTKGIWMAYSSIITTSQGPVPSKGGENIFVMDVEGTDGRERGEDQDFERKAALFALSTSEVLIINVWEHQIGLYQGANMGLLKTVFEVNLSLFGRTKLEMNEHKVLLLFVIRDHIGTTSKESLAATVTQDLIKMWDSLSKPQELAHLQFSDFFDIQFHTLRHKILQPGEFTTDVQLLGDRFTDHKNEDFLFKKYYHHDIPIDGWTMYAENCWDQIDKNKDLDLPTQQILVAKFKCDEILTSVFEEFRSKFEERHAKYAPTDIKEEVDYEELGGSLGDLKEDTLENYDMMASRYNQSVYLQKRKTLEQKITDVYQDLVDQHGAHMVSKLSAKFASSLSSKKLPKDVSFALATEALRKDIVHQFLKNCSCITLNGSLDHAKHVTSFTRKLDSILSKQRFVELNSILAKSLKKVESAVAKAITQEISEPSESTWDRVLEKFKGAQDEYFYSKYETATGVDFGLGTSASVNERALEKFQFRAWSLLHLQMRKLISKDNLVIILKDRFEDKFRYDENGIPRLYQNSHELELNFTAAKEHALKALPILTLATLSDGTTIVPKYDVRDKRLQKKLGAAFDTTGEVDLKDEDVESDTDEEDEDENEPKCFAEAISETDKASVLSKFKKETDATFVESKRALIQHVTHIPYYIYIVILVLGWNEFMAVLRNPFFFTLLLMLGAGTYVLYHLNLLKPAMVVVQRMFDECLVIAKQKLKEFIDEQPQEHAKRLSKMAGITEDKPEEIEMSDLTPPGEGS
What is the function of this protein?
Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network.  Has GTPase activity, which is required for its function in ER organization.
What are the official names of this protein?
Protein SEY1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Enriched in the cortical ER. Concentrated in punctae along the ER tubules.
Protein: NDHM_VITVI
Sequence: MAATSSYTACTKFSMLGWIGGKRELRKRRAFFISAQQQAEVEESQQVNAQEEEQEKMKQQGKQKLPRPVEPQVNVKSKNMSREYGGQWLSSVTRHVRIYAAYIDPVTCEFDQTQMDKLTLILDPTNEFVWTSETCNKVYAYFQELVDHYEGAPLTEYTLRLIGSDIEHYIRKLLYDGEIKYNMNARVLNFSMGKPRILFNDGLPQNVQ
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit M, chloroplastic, NAD(P)H dehydrogenase subunit M, NDH subunit M, NDH-M, NADH-plastoquinone oxidoreductase subunit M.
What is the protein family that this protein belongs to?
Belongs to the NDH complex subunit M family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: PPID_ASHGO
Sequence: MTERQKTYFDLSIGGKPAGRVVFEVYSDVTPKTAENFVRLCAGDAGECRTKPGVPLCYQGSLFHRVIKGFMCQFGDFTNGDGTGGESIYGEKFEDENFARKHDRPFLLSMANAGPNTNGSQCFITCAPTPHLDGKHVVFGEVIQGKRVVRAIERQETAADRPLADVRIDACGILPASYEVPADAEATPADEYGDDYEETLADDAKVDLADPRSVIRAVEAVKAIGTAQLQAARFDVAVQKYAKAAGFLQEYFPDDLPDADVAALEQLKVAVHLNLALAALKAGNHQRVLSAASEVLHGAADDKAKAKALYRRGLAYHHLKDPEMALTDLELAATYQPGDAGIAQAIVNARALKQKLREQQKKALSKMFS
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase D, PPIase D, Rotamase D.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase D subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LHDAG_HDVS1
Sequence: MSQSETRRGRRGTREETLEKWITARKKAEELEKDLRKTRKTIKKLEEENPWLGNIVGIIRKGKDGEGAPPAKRPRTDQMEVDSGPGKRPHKSGFTDKEREDHRRRKALENKKKQLSAGGKILSKEEEEELRRLTDEDEERKRRVAGPRVGDVNPSRGGPRGAPGGGFVPQMAGVPESPFSRTGEGLDIRGTQGFPWVSPSPPQQRLPLLECTPQ
What is the function of this protein?
Following virus entry into host cell, provides nuclear import of HDV RNPs thanks to its nuclear localization signal.  Needs co-infection with hepatitis B virus to provide surface proteins, otherwise there is no packaging or budding.  Packages the HDV ribonucleoprotein in hepatitis B virus empty particles.  Interacts with both HDV genomic RNA and cytoplasmic tail of HBsAg.  May inhibit viral RNA replication (By similarity).
What are the official names of this protein?
Large delta antigen, L-HDAg, p27.
What is the protein family that this protein belongs to?
Belongs to the hepatitis delta antigen family.
What are the subcellular locations of this protein?
Virion. Host nucleus, host nucleolus. Note=isoprenylated in the cytoplasm, and translocates in the nucleus possibly after phosphorylation. Translocates after to nuclear speckle, then to the ER membrane where interaction with Hepatitis B virus antigene takes place (By similarity).
Protein: KRE28_YEAS1
Sequence: MDTGSASIKDYETVLTDIEDSIAVSSEEVLNNQELRLKNTLHEITSSILAINEENKFVNPLRNDESLDVEGKEVFVNPKILSAKIKEFNKLMELLKLTYLEQETLDYFFRFTLSSTKPLQLDSEKDPQFVKLNERVNDLKEEISNVQESKIEQIKAEIQETGHNFAEKQDLINELYLEATGDIENCWDSLNELKNLTNKEDKNMMGEKDTILNSSDSDDFVEETYTNWQKLLFLQKQNQRLTKELKEMHEVKNQIIRKGEQSKKEDSGHLMANESELCQSINLLTKFWEKHFLLKGSKTTILNFEIFTQLGKVQFEIKDMQYIIAISLSDLKRPMIKDITILQKAGGNIVTDIEANSKFNNKYRNNTKVQIFEVMDDIISELTNE
What is the function of this protein?
Forms a kinetochore complex with SPC105 which is required for kinetochore binding by a discrete subset of kMAPs (BIM1, BIK1 and SLK19) and motors (CIN8, KAR3).  Involved in kinetochore-microtubule binding and the spindle assembly checkpoint (By similarity).
What are the official names of this protein?
Spindle pole body component KRE28.
What is the protein family that this protein belongs to?
Belongs to the KRE28 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Chromosome, centromere, kinetochore. Note=Localizes to the nuclear side of the spindle pole body.
Protein: HSP7C_ARATH
Sequence: MAGKGEGPAIGIDLGTTYSCVGVWQHDRVEIIANDQGNRTTPSYVAFTDSERLIGDAAKNQVAMNPINTVFDAKRLIGRRFTDSSVQSDIKLWPFTLKSGPAEKPMIVVNYKGEDKEFSAEEISSMILIKMREIAEAYLGTTIKNAVVTVPAYFNDSQRQATKDAGVIAGLNVMRIINEPTAAAIAYGLDKKATSVGEKNVLIFDLGGGTFDVSLLTIEEGIFEVKATAGDTHLGGEDFDNRMVNHFVQEFKRKNKKDISGNPRALRRLRTACERAKRTLSSTAQTTIEIDSLFDGIDFYAPITRARFEELNIDLFRKCMEPVEKCLRDAKMDKNSIDDVVLVGGSTRIPKVQQLLVDFFNGKELCKSINPDEAVAYGAAVQAAILSGEGNEKVQDLLLLDVTPLSLGLETAGGVMTVLIQRNTTIPTKKEQVFSTYSDNQPGVLIQVYEGERARTKDNNLLGKFELSGIPPAPRGVPQITVCFDIDANGILNVSAEDKTTGQKNKITITNDKGRLSKDEIEKMVQEAEKYKSEDEEHKKKVDAKNALENYAYNMRNTIRDEKIGEKLAGDDKKKIEDSIEAAIEWLEANQLAECDEFEDKMKELESICNPIIAKMYQGGEAGGPAAGGMDEDVPPSAGGAGPKIEEVD
What is the function of this protein?
In cooperation with other chaperones, Hsp70s are key components that facilitate folding of de novo synthesized proteins, assist translocation of precursor proteins into organelles, and are responsible for degradation of damaged protein under stress conditions.
What are the official names of this protein?
Heat shock 70 kDa protein 3, AtHsp70-3, Heat shock protein 70-3, Heat shock cognate 70 kDa protein 3, AtHsc70-3, Heat shock cognate protein 70-3.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 (TC 1.A.33) family. DnaK subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus matrix.
Protein: ASTE_ECO5E
Sequence: MDNFLALTLTSKKPVITEREINGVRWRWLGDGVLELTPLTPPQGALVISAGIHGNETAPVEMLDALLGAISHGEIPLRWRLLVILGNPPALKQGKRYCHSDMNRMFGGRWQLFAESGETCRARELEQCLEDFYDQGKESVRWHLDLHTAIRGSLHPQFGVLPQRDIPWDEKFLTWLGAAGLEALVFHQEPGGTFTHFSARHFGALACTLELGKALPFGQNDLRQFAVTASAIAALLSGESVGIVRTPPLRYRVVSQITRHSPSFEMHMASDTLNFMPFKKGTLLAQDGEERFTVTHDVEYVLFPNPLVALGLRAGLMLEKIS
What is the function of this protein?
Transforms N(2)-succinylglutamate into succinate and glutamate.
What are the official names of this protein?
Succinylglutamate desuccinylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
Protein: NK1R_LITCT
Sequence: MNSNISAQNDSALNSTIQNGTKINQFIQPPWQIALWSVAYSIIVIVSLVGNIIVMWIIIAHKRMRTVTNYFLVNLAFAEASMSAFNTVINFTYAIHNHWYYGLIYCKFHNFFPISAVFTSIYSMTAIALDRYMAIIHPLKPRLSATATKIVICVIWSFSFCMAFPLGYYADVYPMEGGDICYLNWPDSEENRKYEQVYQVLVFCLIYILPLLVIGCAYTFIGMTLWASEIPGDSSDRYHEQVVAKRKVVKMMIVVVCTFAICWLPFHIFFLLQTLHEMTQKFYQQFYLAIMWLAMSSTMYNPIIYCCLNDRFRIGFKHVFRWCPFIRAGEYEGLELKSTRYLQTQSSMYKISRIETTVSSVLNTNDEEAEENGKSSKRLSLDLTSNGSSRSVCKTMSDSSSFYSNNLA
What is the function of this protein?
This is a receptor for the tachykinin neuropeptide substance P.  It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.
What are the official names of this protein?
Substance-P receptor, SPR, NK-1 receptor, NK-1R, Tachykinin receptor 1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: APOD_HUMAN
Sequence: MVMLLLLLSALAGLFGAAEGQAFHLGKCPNPPVQENFDVNKYLGRWYEIEKIPTTFENGRCIQANYSLMENGKIKVLNQELRADGTVNQIEGEATPVNLTEPAKLEVKFSWFMPSAPYWILATDYENYALVYSCTCIIQLFHVDFAWILARNPNLPPETVDSLKNILTSNNIDVKKMTVTDQVNCPKLS
What is the function of this protein?
APOD occurs in the macromolecular complex with lecithin-cholesterol acyltransferase.  It is probably involved in the transport and binding of bilin.  Appears to be able to transport a variety of ligands in a number of different contexts.
What are the official names of this protein?
Apolipoprotein D, Apo-D, ApoD.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted.