PharMolix/UniProtQA huggingface dataset:
Protein: ACSA2_PSEPK
Sequence: MFDIRKYPQALAVSQSAALTPEDYRRLYRQSVEDPDTFWAEQAKRLDWIKPWSSVQQCDLHTGKARWFDGAQLNVSYNCIDRHLAQRGEQTALLWEGDDPKDSKAITYRELHRQVCRLANAMKARGVKKGDRVSIYMPMIPEAAFAMLACTRIGAIHSVVFGGFSPDALRDRILDADCRTVITADEGVRGGKRIPLKQNVDKALASCPAVSSVLVVRRTGGDVAWTEGRDLWYHEATKDAGDDCPPEPMEAEDPLFILYTSGSTGKPKGVLHTTGGYLLQATMTFKVVFDYRDGEVFWCTADVGWVTGHSYIVYGPLANGAISLMFEGVPNYPDTSRFWQVVDKHQVNIFYTAPTALRALMREGSAPLQSTSRKSLRLLGSVGEPINPEAWEWYFEEVGQKRCPIVDTWWQTETGGIMLTPLPGTQSLKPGCATQPMFGVQPVLLDEKGKLIEGPGAGVLAIKASWPGQIRSVYGDHQRMVDTYFKPLPGYYFTGDGARRDADGDYWITGRIDDVINVSGHRIGTAEVESALVLHDSVAEAAVVGYPHDLKGQGVYAFVTTMNGVTPDDTLKAELLALVSKEIGSFAKPELIQWAPALPKTRSGKIMRRILRKIACNELENLGDTSTLADPSVVQGLIDKRLNQ
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase 2, AcCoA synthetase 2, Acs 2, Acetate--CoA ligase 2, Acyl-activating enzyme 2.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: PVDQ_PSEU2
Sequence: MIISRPLCSFVFAGLSFAVILPAQALVEPGNQAARAEIRRTGFGVPHIVAANERGLGYGIGYAYAQDNLCLLANEVVTVNGQRSRYFGPDKATLEQRNNMASDLLFQWLNTPQALADFWNAQPREIRQLMQGYVAGYNRSLAEQTTQGLPQPCAAEWVRPISTDDLLRLTRRLLVEGGVGQFAEALAGATPPAQQKPLQVDAQQAQALQLAAARNQRFALERGSNAVAIGRELSANGRGMLLANPHFPWGGGMRFYQMHLTIPGKLDVMGAALPGLPLINIGFNQHLAWSHTVDTSKHFTLHRLQLDPKDSTRYLLDGQSVAMGKQQVSVDVKQADGSLKSVPRIVYSSIFGPVVQWPGKLDWDSKFAFSLRDANLQNDRVLQQWYAMDKADSLKAFQDSVRKIQGIPWVNTLAVDAQGQALYMNLSVVPNVDAARLARCSDPRIGTELIVLDGSRSECNWEVSAEAAQAGIYPSSRQPQLLRTDFVQHSNDSAWMVNPAAPLQGFSPLISQDGQPLGQRARFALDRLESLKTAGKISVENLQAMVMDNEVYQAGQVLPDLLTFCASELGDDAARLAPLCAALKDWDGRADLNSGIGFVYFQKIMTSMQAVASRWRVAFDPQDPVHTPSGLAIENPSVATALRAAMLAAVDDVAKAGLPAGSKWGDIQVSSISGKQIPIHGGPAGLGVYNAMQTVAGKDGKREVVSGTSYLQVVTFDEQGPKAQGLLAFSESSNPQSAHSSDQTEAFSKKQWQALPFTEQQIKADPAYEVQVISEEPDR
What is the function of this protein?
Catalyzes the deacylation of acyl-homoserine lactone (AHL or acyl-HSL), releasing homoserine lactone (HSL) and the corresponding fatty acid.  Possesses a specificity for the degradation of long-chain acyl-HSLs (side chains of 11 to 14 carbons in length) (By similarity).
What are the official names of this protein?
Acyl-homoserine lactone acylase PvdQ, AHL acylase PvdQ, Acyl-HSL acylase PvdQ.
What is the protein family that this protein belongs to?
Belongs to the peptidase S45 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: NDK_SINFN
Sequence: MAIERTFSMIKPDATKRNLTGAITKMLEDAGLRVVASKRVWMSRREAEGFYAVHKERPFFGELVEFMSSGPTIVQVLEGENAIAKNREVMGATNPANADEGTIRKVHALSIGENSVHGSDGPETAAEEIAYWFAGTEIVG
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIHY_SALG2
Sequence: MLKTVHQKAGRHTRPVRAWLKLLWQRIDEDNMTTLAGNLAYVSLLSLVPLIAVVFALFAAFPMFSDVSIQLRHFIFANFMPATGDVIQRYIEQFVANSNKMTAVGACGLIVTALLLMYAIDSALNTIWRSKRTRPKVYSFAVYWMILTLGPLLAGASLAISSYLLSLRWASDLNTVIDNVLRILPLLLSWISFWLLYSIVPTTRVPNRDALVGAFVAALLFEAGKKGFALYITMFPSYQLIYGVLAVIPILFVWVYWTWCIVLLGAEITVTLGEYRKLKQAAEQEEADQP
What are the official names of this protein?
UPF0761 membrane protein YihY.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPG_CHRSD
Sequence: MAAAKEIRTQIGSIKNTQKITSAMEMVAASKMRKAQERMTASQPYARLIRRVVSHIAKANPEYRHEYMIEREVKRVGYIVVSSDRGLAGGLNINVFKAVTREAKYWHEQGVEVDYAAIGSKANVFFRNHGGNLVAGKSGLGEAPAVDDLIGSVSVMLKAFDEGQLDRLYVVHNEFVNTMTQKPIVRQLLPLEAEAEADDEEETRASGSWDYLYEPDAKTLLDHLLVRYVESQVYQAVVENAACEQAARMIAMKNATDNAGNLIDDLELVYNKARQAAITQEISEIVGGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ATPF_HERAR
Sequence: MNLNATLIAQFVVFFILAGFTMKFVWPPLMNALDERAKKIADGLAAAERGKSDLAAAEKRAQAELTSAQEAGQKRIGDAEKRGQSIIDEAKKTAAEEAARIIATAKADADQQVTQVREALRDQVATLAVKGAEQILKREVNAAVHADLLNQLKAEL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: LPLA_ECOLI
Sequence: MSTLRLLISDSYDPWFNLAVEECIFRQMPATQRVLFLWRNADTVVIGRAQNPWKECNTRRMEEDNVRLARRSSGGGAVFHDLGNTCFTFMAGKPEYDKTISTSIVLNALNALGVSAEASGRNDLVVKTVEGDRKVSGSAYRETKDRGFHHGTLLLNADLSRLANYLNPDKKKLAAKGITSVRSRVTNLTELLPGITHEQVCEAITEAFFAHYGERVEAEIISPNKTPDLPNFAETFARQSSWEWNFGQAPAFSHLLDERFTWGGVELHFDVEKGHITRAQVFTDSLNPAPLEALAGRLQGCLYRADMLQQECEALLVDFPEQEKELRELSAWMAGAVR
What is the function of this protein?
Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.  Is also able to catalyze very poorly the transfer of lipoyl and octanoyl moiety from their acyl carrier protein.
What are the official names of this protein?
Lipoate-protein ligase A, Lipoate--protein ligase.
What is the protein family that this protein belongs to?
Belongs to the LplA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VG52_EHV2
Sequence: MASGGGGGSKRCPKKQPTPEELAEELVKLRMENKALKSKLKEHVGDDDVVLTQAAKEAMVGSVVSGLTRSAAKQIEERIRKETLKATTKNEFEEVIKTLSFRVSLSYADLGGRASSDSSKASKPRGRSKHRAEKQ
What are the official names of this protein?
Gene 52 protein.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae BLRF2 family.
Protein: IF2M_HUMAN
Sequence: MNQKLLKLENLLRFHTIYRQLHSLCQRRALRQWRHGFSSAYPVWTAQLCAWPWPTDVLTGAALSQYRLLVTKKEEGPWKSQLSSTKSKKVVEVWIGMTIEELARAMEKNTDYVYEALLNTDIDIDSLEADSHLDEVWIKEVITKAGMKLKWSKLKQDKVRKNKDAVRRPQADPALLTPRSPVVTIMGHVDHGKTTLLDKFRKTQVAAVETGGITQHIGAFLVSLPSGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQVPIILAVNKCDKAEADPEKVKKELLAYDVVCEDYGGDVQAVPVSALTGDNLMALAEATVALAEMLELKADPNGPVEGTVIESFTDKGRGLVTTAIIQRGTLRKGSVLVAGKCWAKVRLMFDENGKTIDEAYPSMPVGITGWRDLPSAGEEILEVESEPRAREVVDWRKYEQEQEKGQEDLKIIEEKRKEHKEAHQKAREKYGHLLWKKRSILRFLERKEQIPLKPKEKRERDSNVLSVIIKGDVDGSVEAILNIIDTYDASHECELELVHFGVGDVSANDVNLAETFDGVIYGFNVNAGNVIQQSAAKKGVKIKLHKIIYRLVEDLQEELSSRLPCAVEEHPVGEASILATFSVTEGKKKVPVAGCRVQKGQLEKQKKFKLTRNGHVIWKGSLTSLKHHKDDISIVKTGMDCGLSLDEDNMEFQVGDRIVCYEEKQIQAKTSWDPGF
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2, mitochondrial, IF-2(Mt), IF-2Mt, IF2(mt).
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: DYLT3_MOUSE
Sequence: MEGYQRPCDEVGFNADEAHNIVKECVDGVLGGNDYNENNINQWTASIVEQSITHLVKLGKAYKYIVTCAVVQRSPYGFHTASSCFWDTTSDGTCTIRWENRTMNCIVNVFAVAIVL
What is the function of this protein?
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function.  Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.  Probably binds BUB3 as part of transport cargo.  Required for the efficient progression through mitosis.
What are the official names of this protein?
Dynein light chain Tctex-type 3, Protein 91/23, T-complex-associated testis-expressed 1-like.
What is the protein family that this protein belongs to?
Belongs to the dynein light chain Tctex-type family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton. Chromosome, centromere, kinetochore.
Protein: MDM12_USTMA
Sequence: MSLDLDWNLLDDQLSDRFLETINRALEASASKRPSFIGDIQFEKLDFGSDSPDVAIRSITDIWPDFVSIDEPPLRRRGARQTTPASNATTLVESPTDSFGVHHGGVGEIPLRTYTQFDDAAPPNRIHGPPSVVSASVAGSGPMTPAAAAGVANVFSQQWSTALASRGIRAAGMGSATSLPQTQVTSPVDSVPPSPGYFQHWQQHQQLATTGFVPYSVINSRQTSLDASSLRGGGSGPQSSVSQIGVKRDSNSLHPPLGGTYANGLGPRASMRATSAPSFRSISGQNSPGEEREAVASPSSASQLPSLQMRLSLVWPTTTFRLTITTSLLINYPSAAFMSLPLTLSVTGFMMRCGVIVALEGEHQRAHVCLVQEQDDERDPAFVSAGQAAAGSEKKLNSAGINILPQLTFESEVGQHEKHVLKNVGKVEKFIAEVIRKGLEDELVYPNYYTIDLPASKRHSL
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.  The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 12, Mitochondrial inheritance component MDM12.
What is the protein family that this protein belongs to?
Belongs to the MDM12 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: TFPI1_HUMAN
Sequence: MIYTMKKVHALWASVCLLLNLAPAPLNADSEEDEEHTIITDTELPPLKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRIIKTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICEDGPNGFQVDNYGTQLNAVNNSLTPQSTKVPSLFEFHGPSWCLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACKKGFIQRISKGGLIKTKRKRKKQRVKIAYEEIFVKNM
What is the function of this protein?
Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex.  It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.
What are the official names of this protein?
Tissue factor pathway inhibitor, TFPI, Extrinsic pathway inhibitor, EPI, Lipoprotein-associated coagulation inhibitor, LACI.
What are the subcellular locations of this protein?
[Isoform Alpha]: Secreted. SUBCELLULAR LOCATION: [Isoform Beta]: Microsome membrane; Lipid-anchor, GPI-anchor.
Protein: RL1_BORBU
Sequence: MSKKGKKYIEAFSKVDKNKFYNIEDAILLLKEIKFAKFDETIDISINLNLKKNHTVRDTIVLPNQFMKPKRILVFAKGDRADEARAFGATYVGDDDLINKIKSGWDEFDVVVATPDMMKDVGRLGPILGKRGLMPNPKTQTVTNNLKDAINSLKKGRTEFRANKNGVISFSFGKSSMDNEKIKENYEEFVKEVVKKRPSDLKGAFIDSIYISSTMGPSIKVNFVWR
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: PROP1_BOVIN
Sequence: MDTEGSSEQGKQTKEQVCSSLWPEGYPAAETVTSSVDMNTQPYRNLSGVRVGRPKLSLQGVQRGRPHSRRRHRTTFSPAQLEQLESAFGRNQYPDIWARESLAQDTGLSEARIQVWFQNRRAKQRKQERSLLQPLAHLSPATFSGFLPEPPSCPYSYPTPPPPMTCFPHPYNRALPSQPSTGSSFARPYQSEDWYPNLHPTPAGHLACPPPPPMLPLSLEPPKSWN
What is the function of this protein?
Possibly involved in the ontogenesis of pituitary gonadotropes, as well as somatotropes, lactotropes and caudomedial thyrotropes.
What are the official names of this protein?
Homeobox protein prophet of Pit-1, PROP-1, Pituitary-specific homeodomain factor.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL28_SHESW
Sequence: MSRVCQVTGKKPMVGNNRSHAKNATRRRFLPNLQNHRFWLEEEKRFVQLRVSTKGIRLIDKKGIEVVVAELRARGEKV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: HPRK_STRZT
Sequence: MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYFDYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAARECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKSETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGASAVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIEAAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).  The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc. ) in the growth medium.  Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: HGV2_HALRO
Sequence: MVQDTEVVEAGTSKETETTVDVEKEIQECMGAGKKDLLCNDYSEAVNCFQEACTLLSGKHGQMAEECCEAYYYYGVSLLELARLENGVLGNALKGVPEEDADGDSDQEQEQFEKPDLPETEREKLREEVEAAMATEDEDTQEERGCPRRVEKKKEDDKPKESEKSAEKSDEKEKEEKQAKVESSTVKDVKDEKSSDKPVESSNTEEPGTSGTSASSSKENESEEDPDDISNMQLAWEMLELAKVLYKKHDKSKTNKQMVAQCHLKLGELGLEVENHPQAIGDFLECLVIQKDLLPETDRKLAETYYNLGLAYSFEKRYDNALEHYQSALDVLEARVDMLNELIESNEGNKEKEKEIISECKEVGELKELIPDINSKIEDVILAKKQMQKLDGSPFRQASEGESSSGLGASTSDDKPCSTIPIRKVAPTSVPVAKDSPSDITHLVRRKRPSPDEDNQPAESKENESKKAKQEETEEATNGHSAVKKDTDVTDKNGTNGHSKTPKKDAAKRR
What is the function of this protein?
May function as a nucleosome assembly factor during rapid embryonic cell divisions.
What are the official names of this protein?
Protein HGV2.
What is the protein family that this protein belongs to?
Belongs to the NASP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MOS_ATHSQ
Sequence: SSVNARPCSSPLVCPAKGENFFGVGNVARIRRLPPHLAWCSIDWDQLCLLHLLGSGGFGSVYKAIYHGATVAVKKVKRCSKNHLASRQSFWAELNVARLGHNNVVRIVAASTCTPASQDSLGTIIMEYAGNCTLHHVIYGTGYLTGNNSDSLKCDHGFLSTAQAVIYSHDIVAGLMFLHSQLIVHLDLKPANIF
What are the official names of this protein?
Serine/threonine-protein kinase mos, Oocyte maturation factor mos.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: LFTR_CUPTR
Sequence: MIAWLDPQDPFPPVEHALGPDSEAPGLLAASRELSPQRLLLAYRQGIFPWYSSGQPVLWWSTDPRMVLAPPALRVSVNLRKTLRRVLRDADWEIRVDHDFLAVMRACASTPREGQDGTWITDAIIAAYGALHRNGLAHSVESWYRGERVGGLYGVALGRMFFGESMFAHRTDASKIALAALCAFLGNHGVAMIDCQQETDHLASLGARPIPRAEFVAHVRAATAQPAISPWRFDKSVLERWAGTPAAPAA
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPT_LISIN
Sequence: MFKKLFRQDGNILNSELAEDLPIPRHVAIIMDGNGRWAKKRFLPRIAGHKEGMDVVKRVTRYANAIGIDVLTLYAFSTENWKRPTDEVDFLMKLPVEFFDSFVPELIEENVRVNVMGYRENLPEHTMRAVEKAIADTAHCTGLTLNFALNYGGRSEIITAAKEAMKELVSEGKTSEDLTEELLNDHLMSHGLGDPDLLIRTSGELRLSNFMLWQLAYSEFYFTETHWPDFSKEDFLQAIIEYQNRSRRFGGL
What is the function of this protein?
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
What are the official names of this protein?
Isoprenyl transferase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: RL6_SHIF8
Sequence: MSRVAKAPVVVPAGVDVKINGQVITIKGKNGELTRTLNDAVEVKHADNTLTFGPRDGYADGWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGNVINLSLGFSHPVDHQLPAGITAECPTQTEIVLKGADKQVIGQVAADLRAYRRPEPYKGKGVRYADEVVRTKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RM04_MAGO7
Sequence: MASSGAARPAASRVLQRCQPFSSSTSCAAPVTTWRTLARPSTAAATAQATTQQLRLLSISMPLQKRRTTRDNNRLRGQSTIHRSGIRRPLSVSEEDIPQPVQDEGVGKMREEDTDPDHGLWGFFYDKQLVPTPKQLSAHGRSWTVQELRGKSWEDLHALWWMCCRERNRIATAIRTRQFIGIKKDNPFDEAEARGRTVNKTMQAIKHVLTERFYAWEDARKLAMEDPEINLSGKGPIYTPSLHFESADTSSYIEEPVADHLETPETSGQEKVGELSPAGAVDPSTILASKTGKPVTDAPRSS
What are the official names of this protein?
54S ribosomal protein L4, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: UVRC_MYCMS
Sequence: MSLKQQVDLLPNKPGCYLFFNKDNDVIYVGKAKNLKKRVSTYFNKAYNIKTTRLVREITDLKYFIVDNEKESLLLEKNLIKKYHPKYNVLLNDDKTYPYIIITNQKDPMYKYVRKYDKKALKNYGPLPIGSNARSILLTLQRLFPLRMCQGNLNKPCLYYHLNQCSGACFKQVDPSYYEYQIKQVDKFFKGEINQVKQTLVKQMQKASDNLQFEQAQRIKDQITSLDFITAKQNVDIVTNKNIDVVNYEINQDKICFVILFYRLGQLTYKDEYIQNYEGQNLSELFNSYLQQIYQKNIYPDVLLIPNEIELLDLDQNLLEFSSYSLNKQDDVFIKLAKQNAIDSLNKSVISHNVNSGDEIEILEQLKQISNASKYLKRIEVFDISNIYSQFITGACIVYINAKPIRNEFRKYNIDPSYTSDFSRMKFMLEKRFLKQIKEKEQLPDLVIVDGGIIQIHAAKEVLNKLNLKIDVIGLSKDDHHKTRYLIDIFEQTIDIKNFKKLYNFLTSLQIRVDEYAKSGFRKKYHNQLNDQILLIKGVGKKTNLKLYKHFKTIDNIKNASFDELNKVINNKKITNLIISNLNK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ODP2_MYCTO
Sequence: MAFSVQMPALGESVTEGTVTRWLKQEGDTVELDEPLVEVSTDKVDTEIPSPAAGVLTKIIAQEDDTVEVGGELAVIGDAKDAGEAAAPAPEKVPAAQPESKPAPEPPPVQPTSGAPAGGDAKPVLMPELGESVTEGTVIRWLKKIGDSVQVDEPLVEVSTDKVDTEIPSPVAGVLVSISADEDATVPVGGELARIGVAADIGAAPAPKPAPKPVPEPAPTPKAEPAPSPPAAQPAGAAEGAPYVTPLVRKLASENNIDLAGVTGTGVGGRIRKQDVLAAAEQKKRAKAPAPAAQAAAAPAPKAPPAPAPALAHLRGTTQKASRIRQITANKTRESLQATAQLTQTHEVDMTKIVGLRARAKAAFAEREGVNLTFLPFFAKAVIDALKIHPNINASYNEDTKEITYYDAEHLGFAVDTEQGLLSPVIHDAGDLSLAGLARAIADIAARARSGNLKPDELSGGTFTITNIGSQGALFDTPILVPPQAAMLGTGAIVKRPRVVVDASGNESIGVRSVCYLPLTYDHRLIDGADAGRFLTTIKHRLEEGAFEADLGL
What is the function of this protein?
Appears to be essential for Mtb pathogenesis.
What are the official names of this protein?
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, Component of peroxynitrite reductase/peroxidase complex, Component of PNR/P, Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex, Pyruvate dehydrogenase complex component E2, PDH component E2.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoacid dehydrogenase family.
Protein: COPB2_SCHPO
Sequence: MMRLDFQRKLLSHTERVKAVDFHPTEPWVIASHYNGQVGIWNYNTQTLVRSFDINDVPIRACAFIARKNWFVCGSDDFQVRVYNYNTGEKVTQFEAHPDYIRALVVHPTQPFLLTSSDDMTIKCFNWDMSWKCVQTFEGHSRYVMSLAINPKDTNTFASSCLDGTVKVWSFGSSVANFTLQAHDRGVNYVNYYPAGDKPYLITAGDDNLIKVWDYQTKACVRILEGHTNNVSFAFFHSKFPIIISGSEDGTVKIWHTLSYSLIKSYNFSLDRAWCIAQNKDNGLVTVGFDNGLITFSLGRDEPSVTMDSSGKVVWSNYNEVMSAMIRPAKEQSDLTDGSLISLSVKELGTTELYPAVLKHSPNGRFVSVCGNGEYIVYTALAWRNKAYGKALDFAWSADSNVYGSRTSDRSIVIHKNFKESNRLDLSYSCDKIFGGFLLGVVGSDFICFYDWDTGILVRKIDVKPKGVYWNDDGRFVILACDDDFYLLGFNAEMFYSAVESGTADEEEGVADSFEALADVSESVVNGKWVAETFIYTTTAARLNYLIGDQTYKIANVESSFYLLGYIPRDDRIYLTDRDMNVVSYSFNLAIIEYQSLVLKGDLEAAQGLLEQISETDRPRLSDFLSRLGYKEAALELSGDSVQRFELALDAQRLDIASQIAQELDDPLKWRSLGDAALNAWDFVLAQECFEKGKDYGSLVLLYTATNNHEGLKELSQLTKSTKINNTAFICSWLTNQPAECVNILTSTQRYPEANLFAATYCPDEVKNVLPEWKVDLTKNQKERIADSLGDLELKN
What is the function of this protein?
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.  Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).
What are the official names of this protein?
Probable coatomer subunit beta', Beta'-coat protein, Beta'-COP.
What is the protein family that this protein belongs to?
Belongs to the WD repeat COPB2 family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.
Protein: TRUA_STRP7
Sequence: MTRYKATISYDGYAFAGFQRQPHARSVQEEIEKTLTRLNKGQAITVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHCRYAKHSKTYEFTVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTASGTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQIDLILEKKDRQLAGPTAAPNGLYLKEIRYEE
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.