PharMolix/UniProtQA huggingface dataset:
Protein: MURD_LEPIC
Sequence: MKFPESLKGLKILVLGGGISGNSALNFLISEKAQPILCDRNQPERTVVPFFPDNIPPQSLPEVSLVIKSPGILPTHPILSYAADKKIPVVSEIDLGRYFFKGKIIGITGTDGKSTTTSLIAHLLKESFPDLKEGGNLGIPFTSFCKESISLAVLELSSYQLEDSSPLHLDVSVFLNLASDHLERHKTMENYFQAKLKIADLSNSNHTLIVSEKIKERILNSISYQCKLLSFGKTSDSNAFLDENSLKIKTSKFVYDISKFYLPGTHNRENLAASILAAEEIGGKPESIQTRIPLFRGLPHRFQIAGEKLGISFINDSKSTNLHSMLAGMATWKNIDQTCLILGGRPKQEDLKPLYNFLIKGIGCVVLFGEARATWESGIKNIIGEKLYCVENLNDTFEIFKKGNIFPVPGLNKDIIIRLSDSISISSFVFSPACASFDQYKNFEERGNHFLSLVNDFLDQIDS
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANMK_SHEB2
Sequence: MKNAYYIGLMSGTSMDGVDAVLVDFSGAQPQLIASHTEAIPSHLLKGLQRLCSPSTDEINRLGRLDRNVGELFALAVNNLLTKCAIAKEEVIAIGSHGQTVRHMPNLEVGFTLQIGDPNTIATETGIDVIADFRRKDIALGGQGAPLVPAFHQQTFAEVGKKRIILNIGGIANITYLPGNSDQVLGFDTGPGNTLVDAWIQQVKSEPFDRDGAWAASGKTDQDLLTQLLSHPYFSLAYPKSTGRELFNQAWLEQQLSPFNHLDEEDIQSTLLDLTCHSIARDMIKLSNEGELYVCGGGAFNGQLMQRLAALLPGYTLNTTSALGVDPKWAEGIAFAWLAMRNHLGLPANLPAVTGASREAVLGGRFSAK
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: TCAL8_MOUSE
Sequence: MQKSCDENEGTPQNTPKADEGHPSEDPPQQAGETLQASGENVREETEGSHRGEPAEPSPEPKEDTPARHLNPEEVIRGVDELERLREEIRRVRNKFVLMHWKQRHSRSRPYPVCFRP
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Transcription elongation factor A protein-like 8, TCEA-like protein 8, Transcription elongation factor S-II protein-like 8.
What is the protein family that this protein belongs to?
Belongs to the TFS-II family. TFA subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RUVA_HYDCU
Sequence: MIGFLSGTLHAKLPPQILINVNGVGYEVEAPMSTFYAIGEVGDEVMLLTHMHVREDAMLLFGFASELERSLFKELIKVNGIGAKMAIGILSAMSVNDFVGLVDVGDAPALTKIPGVGKKTAERLVIEMRDRLKGWGNGASSNVSSKTMVSSAPHNQKASAVEALISLGYKTAQADKMVQAVESGLSLEETIKKALQSVKL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: FTSH_ENDTX
Sequence: MKKSNPWFVFFWITLLVIVLMFINFARQGGNEVELEYSQFKQHIKAGSVFKVLVAPGLIRGQFRDGDGVFKRFKTVPMDDPNLVKDMEDNKVLEFSATEKSGWLGSLLLNWGPVVLLILFCFWMMRGMSMGNKQAMSFGKTKAKLAVGASKKITFKDVAGCDEAKEELQELIEFLKDPARFQKLGGKIPKGVLLFGSPGTGKTLLAKAVAGEANVPFFSSSGSEFVEMFVGVGASRVRDLFDHGRKSAPCLLFIDEIDAVGRHRFAGIGGGHDEREQTLNQLLVEMDGFDSKEGVILIAATNRPDVLDPALLRPGRFDRQVIILSPDLKDREEILGVHSKKIRLDNDVNLNVIARRTPGFVGADLANLVNEAALLAARNSQNAVNMKNMEEAIDRILAGPQRKSRLMSDKEKNIIAYHEAGHTLVAKFLPSADPVHKVSIIPRGPALGYTLQLPEEDKYLTSKSELLDKLSILFGGRVAEELVFSEITTGAQNDISKATGIAMRMVTEFGMSDKIGPMALQRPNEEVFLGRDISRDARHSGKTSELIDEEVKNIIYSSKSRASKIIKDNVSILNKIVSYLLERENLSGEDIDKIIKGEELAPLSESSSVDEETKKKSTVEKKVINEKVIIS
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: RP54_ECOLI
Sequence: MKQGLQLRLSQQLAMTPQLQQAIRLLQLSTLELQQELQQALESNPLLEQIDTHEEIDTRETQDSETLDTADALEQKEMPEELPLDASWDTIYTAGTPSGTSGDYIDDELPVYQGETTQTLQDYLMWQVELTPFSDTDRAIATSIVDAVDETGYLTVPLEDILESIGDEEIDIDEVEAVLKRIQRFDPVGVAAKDLRDCLLIQLSQFDKTTPWLEEARLIISDHLDLLANHDFRTLMRVTRLKEDVLKEAVNLIQSLDPRPGQSIQTGEPEYVIPDVLVRKHNGHWTVELNSDSIPRLQINQHYASMCNNARNDGDSQFIRSNLQDAKWLIKSLESRNDTLLRVSRCIVEQQQAFFEQGEEYMKPMVLADIAQAVEMHESTISRVTTQKYLHSPRGIFELKYFFSSHVNTEGGGEASSTAIRALVKKLIAAENPAKPLSDSKLTSLLSEQGIMVARRTVAKYRESLSIPPSNQRKQLV
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  This sigma factor is responsible for the expression of enzymes involved in arginine catabolism.  The open complex (sigma-54 and core RNA polymerase) serves as the receptor for the receipt of the melting signal from the remotely bound activator protein GlnG(NtrC).
What are the official names of this protein?
RNA polymerase sigma-54 factor.
What is the protein family that this protein belongs to?
Belongs to the sigma-54 factor family.
Protein: ADDB_LACLA
Sequence: MEILYTEITQDLTEGLLEISLEELEKNRKVYYIVPSSMSFEKEKEILERLAKGSDSAVFDLLVTRFKQLPYYFDKREKATTKTELGTAGLSMLFRRVLRSFSKEEIPLYFSLQDSAGFLEMLIQLRTELLTANLSVENLPDSPKNQELKKILSRFEEKLANDYANYSEFGDFTSRLADGEFDFQLKDVTIVIDGYTRFSAEEELFIESIQDRVARFVIGTYSDENSLTAGSETIYISTSQMIGRFRSKFPVELRKMAFSSVNEVYNKLTKLLDLDSRFAISDQNIEINSADAKYFRIWEAENQKVEIEGVAKEIRQKISQGAFFKDFTVLVGDPAAYEITLKEIFELYEIPFFYAQEESMSQHPLVIFFESLLSIKKNNYGTDDVVNLLKSKVYTDVNLDEEVIDYFEYYVQKYKISGRKKFTEAFNESEFSKIELVNQLRENLLGNDSPLQVFLGTNRQKTGKKWVSDLQVLLENGNVMANMNTYFSEAESENKHQMADKHEQVWQMLISILNEFLAVFSDEKLKSVEFLDILLAGLKNAKYRQIPANVDVVNIKDYELVEPKTNKYIYAIGLSQTNFPRIKKNSTLLSDEERLEINQTTDENQFIEQLNVVNYQKNQFTVLSLVNSAKETLVLSMPQIMANEQGEFSPVFQLFLNHSDEKILQKIQEVNLFESLEHIGNSRSVISMIGKIERELVETEEKNDDKRVFWSSIFRILVKSNPDFQKILLDLAKDIDTVNLSQETLDQIYGDKLYASVSSFERFYNCEYQYFLETTLGLETFENIDINSKIVGNFFHEVFEKVMQEEALSAENFDEKLTKVLHDVDSNYSRYFTHDATARFTWTNLEEIVRQTATVLKETVSTDELKTLLTESSFGLPKSELGNFSVDDIYLRGRIDRLDQLSSDYLGAIDYKSSAHSFKLQDAYDGLSLQFMTYLDVIKEAFPNQKIWGALYLQFKNQPINLSEINHLSEIAGLLKESMRYDGLVLEEAADQIKAIENITVKKSNIYNQEEFEQLLKLNENHYQHAGQRLKSGQIAINPIMKRSEGIDQTGNVRGCRYCPLKSICRFEANVHMNDHSREIGQKSQAEILAELKGEGRNE
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  This subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease RexB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 2 subfamily.
Protein: FDM1_ARATH
Sequence: MSISDEEAEISESEIEDYSETPYRLLRDGTYKVKVNGQLRCPFCAGKKKQDYKYKELYAHATGVSKGSATRSALQKANHLALAMFLENELAGYAEPVPRPPVVPPQLDETEPNPHNVYVWPWMGIVVNPLKEADDKELLLDSAYWLQTLSKFKPIEVNAFWVEQDSIVGVIAKFNGDWSGFAGATELEKEFETQGSSKKEWTERSGDSESKAYGWCARADDFESQGPIGEYLSKEGQLRTVSDISQKNVQDRNTVLEELSDMIAMTNEDLNKVQYSYNRTAMSLQRVLDEKKNLHQAFADETKKMQQMSLRHIQKILYDKEKLSNELDRKMRDLESRAKQLEKHEALTELDRQKLDEDKRKSDAMNKSLQLASREQKKADESVLRLVEEHQRQKEDALNKILLLEKQLDTKQTLEMEIQELKGKLQVMKHLGDDDDEAVQKKMKEMNDELDDKKAELEGLESMNSVLMTKERQSNDEIQAARKKLIAGLTGLLGAETDIGVKRMGELDEKPFLDVCKLRYSANEAAVEAATLCSTWQENLKNPSWQPFKHEGTGDGAEEVVDEDDEQLKKLKREWGKEVHNAVKTALVEMNEYNASGRYTTPELWNFKEGRKATLKEVITFISNDIKILKRKRT
What is the function of this protein?
Forms a complex with IDN2 and FDM2/IDNL2 that is required for RNA-directed DNA methylation (RdDM) and that functions at a downstream step of the RdDM pathway (PubMed:22302148, PubMed:22757778, PubMed:22570638, PubMed:22592791).  Required for de novo DNA methylation and 24 nucleotide small interfering RNA (siRNA) accumulation (PubMed:22570638).  Binds unmethylated but not methylated DNAs through its coiled-coil domain (PubMed:22757778).  May bind double-stranded RNAs (dsRNAs) with 5'-overhangs through its XS domain (PubMed:22302148, PubMed:22757778).  However, according to (PubMed:22570638), FMD1 does not bind dsRNAs.
What are the official names of this protein?
Factor of DNA methylation 1, Protein IDN2 PARALOG 1, Protein IDN2-LIKE 1.
Protein: OAF_HUMAN
Sequence: MRLPGVPLARPALLLLLPLLAPLLGTGAPAELRVRVRLPDGQVTEESLQADSDADSISLELRKPDGTLVSFTADFKKDVKVFRALILGELEKGQSQFQALCFVTQLQHNEIIPSEAMAKLRQKNPRAVRQAEEVRGLEHLHMDVAVNFSQGALLSPHLHNVCAEAVDAIYTRQEDVRFWLEQGVDSSVFEALPKASEQAELPRCRQVGDHGKPCVCRYGLSLAWYPCMLKYCHSRDRPTPYKCGIRSCQKSYSFDFYVPQRQLCLWDEDPYPG
What are the official names of this protein?
Out at first protein homolog, HCV NS5A-transactivated protein 13 target protein 2.
What is the protein family that this protein belongs to?
Belongs to the OAF family.
Protein: CBID_CITBB
Sequence: MSGKELRYGFTTGACAAAAVKAAAQMLRDQGMVHEVELMLPCGIGASFQVHGGVLRDNTASCYVVKDAGDDPDVTNGAEIHVTASIEFFTKNRIVIEGGTGIGRVTKPGLAVPVGEWAINPVPRSMILEVVKEVFALRCIPATLTFNISIPNGEELAKKTLNERLGIVGGLSILGTTGIVKPISAKAWTDTVDASVDVALACGARTVVLATGRSSEIVAQKHLALSEEAFVMMGDHFGYAMRSCASKEVPEVVVAGQFAKLVKIACGHEQTHVTSSQMDLDALAWWLREVPATAHLEQMAREANTARHLLEASGYNQAVIELVCSRVLKVCAEVAPWVKMRVMLAGYHGELLYFTP
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: CH60_HUMAN
Sequence: MLRLPTVFRQMRPVSRVLAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKEIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSIQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTKDDAMLLKGKGDKAQIEKRIQEIIEQLDVTTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALDSLTPANEDQKIGIEIIKRTLKIPAMTIAKNAGVEGSLIVEKIMQSSSEVGYDAMAGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEVVVTEIPKEEKDPGMGAMGGMGGGMGGGMF
What is the function of this protein?
Chaperonin implicated in mitochondrial protein import and macromolecular assembly.  Together with Hsp10, facilitates the correct folding of imported proteins.  May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix (PubMed:1346131, PubMed:11422376).  The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back-to-back double ring.  In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per ring, followed by the binding of ATP and association with 2 heptameric rings of the co-chaperonin Hsp10.  This leads to sequestration of the substrate protein in the inner cavity of Hsp60 where, for a certain period of time, it can fold undisturbed by other cell components.  Synchronous hydrolysis of ATP in all Hsp60 subunits results in the dissociation of the chaperonin rings and the release of ADP and the folded substrate protein (Probable).
What are the official names of this protein?
60 kDa heat shock protein, mitochondrial, 60 kDa chaperonin, Chaperonin 60, CPN60, Heat shock protein 60, HSP-60, Hsp60, HuCHA60, Mitochondrial matrix protein P1, P60 lymphocyte protein.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RK13_GUITH
Sequence: MNKTIIREGKINLGKWFIIDATDKNLGRLASETAKTLVGKYDPLYAPNVNPKNIIVIINADKIRVTGNKKFDKFYYRHSGQVGGLTIETFNELQSRLPGRILEKAVKGILPKGPLGRELFNNLKVYAGSSHPHEAQNPVALVM
What are the official names of this protein?
50S ribosomal protein L13, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MLP2_YEAST
Sequence: MEDKISEFLNVPFESLQGVTYPVLRKLYKKIAKFERSEEEVTKLNVLVDEIKSQYYSRISKLKQLLDESSEQKNTAKEELNGLKDQLNEERSRYRREIDALKKQLHVSHEAMREVNDEKRVKEEYDIWQSRDQGNDSLNDDLNKENKLLRRKLMEMENILQRCKSNAISLQLKYDTSVQEKELMLQSKKLIEEKLSSFSKKTLTEEVTKSSHVENLEEKLYQMQSNYESVFTYNKFLLNQNKQLSQSVEEKVLEMKNLKDTASVEKAEFSKEMTLQKNMNDLLRSQLTSLEKDCSLRAIEKNDDNSCRNPEHTDVIDELIDTKLRLEKSKNECQRLQNIVMDCTKEEEATMTTSAVSPTVGKLFSDIKVLKRQLIKERNQKFQLQNQLEDFILELEHKTPELISFKERTKSLEHELKRSTELLETVSLTKRKQEREITSLRQKINGCEANIHSLVKQRLDLARQVKLLLLNTSAIQETASPLSQDELISLRKILESSNIVNENDSQAIITERLVEFSNVNELQEKNVELLNCIRILADKLENYEGKQDKTLQKVENQTIKEAKDAIIELENINAKMETRINILLRERDSYKLLASTEENKANTNSVTSMEAAREKKIRELEAELSSTKVENSAIIQNLRKELLIYKKSQCKKKTTLEDFENFKGLAKEKERMLEEAIDHLKAELEKQKSWVPSYIHVEKERASTELSQSRIKIKSLEYEISKLKKETASFIPTKESLTRDFEQCCKEKKELQMRLKESEISHNENKMDFSSKEGQYKAKIKELENNLERLRSDLQSKIQEIESIRSCKDSQLKWAQNTIDDTEMKMKSLLTELSNKETTIEKLSSEIENLDKELRKTKFQYKFLDQNSDASTLEPTLRKELEQIQVQLKDANSQIQAYEEIISSNENALIELKNELAKTKENYDAKIELEKKEKWAREEDLSRLRGELGEIRALQPKLKEGALHFVQQSEKLRNEVERIQKMIEKIEKMSTIVQLCKKKEMSQYQSTMKENKDLSELVIRLEKDAADCQAELTKTKSSLYSAQDLLDKHERKWMEEKADYERELISNIEQTESLRVENSVLIEKVDDTAANNGDKDHLKLVSLFSNLRHERNSLETKLTTCKRELAFVKQKNDSLEKTINDLQRTQTLSEKEYQCSAVIIDEFKDITKEVTQVNILKENNAILQKSLKNVTEKNREIYKQLNDRQEEISRLQRDLIQTKEQVSINSNKILVYESEMEQCKQRYQDLSQQQKDAQKKDIEKLTNEISDLKGKLSSAENANADLENKFNRLKKQAHEKLDASKKQQAALTNELNELKAIKDKLEQDLHFENAKVIDLDTKLKAHELQSEDVSRDHEKDTYRTLMEEIESLKKELQIFKTANSSSDAFEKLKVNMEKEKDRIIDERTKEFEKKLQETLNKSTSSEAEYSKDIETLKKEWLKEYEDETLRRIKEAEENLKKRIRLPSEERIQKIISKRKEELEEEFRKKLKENAGSLTFLDNKGSGEDAEEELWNSPSKGNSERPSAVAGFINQKNLKPQEQLKNVKNDVSFNDSQSMVTNKENNIVDSSAAGNKAIPTFSFGKPFFSSNTSSLQSFQNPFTASQSNINTNAPLRTLNIQPEVAVKAAINFSNVTDLTNNSTDGAKITEIGSTSKRPIESGTSSDPDTKKVKESPANDQASNE
What is the function of this protein?
Together with the closely related MLP1, involved in the structural and functional organization of perinuclear chromatin (PubMed:10638763).  MLP1/MLP2 associate with the nuclear pore complex and form filamentous structures along the nuclear periphery (PubMed:10085285, PubMed:24152732, PubMed:10617624).  Has a role in the localization of Esc1 to nucleolar regions (PubMed:24152732).  Together with MLP1, mediates tethering of the some telomeres to the nuclear periphery, probably mediated by YKU70/YKU80 (HDF1/HDF2) heterodimer and show perinuclear location dependent silencing (PubMed:11862215).  MLP1 and MLP2 are involved in telomere length regulation but not silencing or telomere anchoring (PubMed:12490156).  Plays a role in the incorporation of components into the spindle pole body (PubMed:10617624, PubMed:14718167, PubMed:16027220).  Involved in double-strand break repair, probably also mediated by the YKU70/YKU80 (HDF1/HDF2) heterodimer (PubMed:10638763, PubMed:14718167, PubMed:16027220).
What are the official names of this protein?
Protein MLP2, Myosin-like protein 2.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Nucleus, nuclear pore complex. Note=Nuclear periphery, excluded from nuclear envelope adjacent to nucleolus.
Protein: MSRB_ENTFT
Sequence: MTKPTEEELKQTLTDLQYAVTQENATERPFSGEYDDFYQDGIYVDIVSGEPLFSSLDKYDAGCGWPSFTKPIEKRGVKEKADFSHGMHRVEVRSQEADSHLGHVFTDGPLQEGGLRYCINAAALRFVPVADLEKEGYGEYLSLFK
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: YDED_SCHPO
Sequence: MVGTSSLDISMSGSSSSDAEQWEKQTKSVHIDNSDVNSLILDYLVIQGDEEAAKTFAEEAQITDYYIPPYVKERLEICELIKSGSINSAICKLNELEPEILDTNSELLFELLRLRLLELIREVVEEKDTSDLAVERCLNFAHENLAPLAPSNQKFLNSLELTMSLLCFPPSSYSPALKNVLNYSQRERVANLANVSILKSQGLSNESRLLSLVNFERWCEKEAQRNSIEVQKFVPKASIK
What are the official names of this protein?
Uncharacterized protein C12B10.13.
Protein: HSLV_STAAM
Sequence: MSNTTLHATTIYAVRHNGKAAMAGDGQVTLGQQVIMKQTARKVRRLYEGKVLAGFAGSVADAFTLFEKFETKLQQFSGNLERAAVELAQEWRGDKQLRQLEAMLIVMDKDAILVVSGTGEVIAPDDDLIAIGSGGNYALSAGRALKRHASHLSAEEMAYESLKVAADICVFTNDNIVVETL
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MELT_CAEEL
Sequence: MHFLLSRLLHHRQLNVSAQLFNVSHYDVITDMSNTFTCLKEILNAPSYPSNKVDQSVVEIVVARLTAAIRETGSIESYAAELVDVLDEVLRHPMTTLNEKCQDVDSPHCKIASDLLSSLFLHYGNKPVMTLTIPVALKCLNSENGELVKNTTSYISLAAIHNGKSLSSHALQIISNVVRGNYSLIRVLPHIYPDNKEPFHAQLSQLIDLLQNTEVDCSEKLSLLQLSSMVANTKPDVLIPFLPRFDVYLLSPQMSTALLNIYMSLISQNRTKSLSQFLPTLKLAAQSNEFINNRTTICKIIANIGRVSSPLASEAVDELVLMARNNSSDQQILQTVLNEIDAIGSIHPTSLRRHVSFFQTLPTSRIIERILAHLNPNNSENIMSYDIKEQSTESLLSKNSKVFGNLITSGGRTVFEVCDSPTVELCELDRNTHSLAMQYQNNRSSGSLSRRSHASIAHSLGAGTHGPYSDINESRELSMISMPSSSRTNVLLAQPTSSSTSRIQTLPHAFAPQAMTQIQMGKDGRVRPVGGGRRPVQWPAGSTETTFPAHLGPITTSKMCALNEEDEKWINNDRNDVVYKFVEHRKNKIRRYIGEVNARFPVPVQCTVEGSKNSKHRMVIHFSCQTRSSPCCVFTKEYLFAFKTKYPAFWLHFMFLQMECSAITQFGEVVGKDSQQYQTLEHCWKCLPSSITKSVPFDTMITAAFPNSKDQNKLIKELDEAGFFACFTMDSTNNMWNCISCTNPEKVKYFVEEGGAEKVLEGQLKEKKGRWRFLKRWNTKYFTLSSAALNYSTQHMPTDSRALLPSIDLRSIRSVRSLGRGKKARKSLRKAFEIFTADNTSMILKAKDEKNAEEWLHCLQIAMAHARRELA
What are the official names of this protein?
Protein melted homolog.
What is the protein family that this protein belongs to?
Belongs to the MELT/VEPH family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MSN2_YEAST
Sequence: MTVDHDFNSEDILFPIESMSSIQYVENNNPNNINNDVIPYSLDIKNTVLDSADLNDIQNQETSLNLGLPPLSFDSPLPVTETIPSTTDNSLHLKADSNKNRDARTIENDSEIKSTNNASGSGANQYTTLTSPYPMNDILYNMNNPLQSPSPSSVPQNPTINPPINTASNETNLSPQTSNGNETLISPRAQQHTSIKDNRLSLPNGANSNLFIDTNPNNLNEKLRNQLNSDTNSYSNSISNSNSNSTGNLNSSYFNSLNIDSMLDDYVSSDLLLNDDDDDTNLSRRRFSDVITNQFPSMTNSRNSISHSLDLWNHPKINPSNRNTNLNITTNSTSSSNASPNTTTMNANADSNIAGNPKNNDATIDNELTQILNEYNMNFNDNLGTSTSGKNKSACPSSFDANAMTKINPSQQLQQQLNRVQHKQLTSSHNNSSTNMKSFNSDLYSRRQRASLPIIDDSLSYDLVNKQDEDPKNDMLPNSNLSSSQQFIKPSMILSDNASVIAKVATTGLSNDMPFLTEEGEQNANSTPNFDLSITQMNMAPLSPASSSSTSLATNHFYHHFPQQGHHTMNSKIGSSLRRRKSAVPLMGTVPLTNQQNNISSSSVNSTGNGAGVTKERRPSYRRKSMTPSRRSSVVIESTKELEEKPFHCHICPKSFKRSEHLKRHVRSVHSNERPFACHICDKKFSRSDNLSQHIKTHKKHGDI
What is the function of this protein?
Positive transcriptional factor that acts as a component of the stress responsive system.  Recognizes and binds to the stress response element (STRE) which is involved in the response to various forms of stress (heat, oxidative, osmotic, etc. ).  Involved in the regulation of the CTT1, DDR2, HSP12 genes.  May be regulated via WHI2-PSR1 complex phosphatase activity.
What are the official names of this protein?
Zinc finger protein MSN2, Multicopy suppressor of SNF1 protein 2.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: OBG_VESOH
Sequence: MKFVDSASVRIEAGKGGAGCLGFRRERYISDGGPDGGDGGDGGHVYFQGQDGLNTLSEFCFKRLFRAKNGQPGSGQNKRGKSAQHLTVEIPLGTKVYDLVTDELIGEMTKHEQTILVAKGGFHGLGNTRFKSSINRAPRETTPGFPGEVREIGLELSVMADIGLLGIPNAGKSSLIRQISSARPKIADYPFTTLHPSLSVVSFCDKHIVMADIPGLIENASKGAGLGFKFLKHLSRAKVLLHVVDILPVDGSDPVKNFLTIEKELKKYDQELANKEKLLVINKIDLLPEKDRNTMVQSLLKDICYKGKVFNISALNGLGCKDLVAGLFKLVLRK
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYI_LISMC
Sequence: MEYKDTLLMPKTDFPMRGNLPNKEPEWQAKWEEEKLYEKIQEKNAGRKAYILHDGPPYANGELHMGHALNKTIKDIIVRYKSMAGFSSPYVPGWDTHGLPIETAIAKKGVKRKEMSIAEFRKLCAEYAMTQVDGQRTGFKRLGINGDWENPYITLLPEYEAEQIKVFGEMAKKGYIYKGKKPVYWSPSSESALAEAEIEYQDKKSASIFVAFKVTDGKGVLDEGTNIVIWTTTPWTIPANMGITVNPDLDYVVIESAGEKYVVAEALLPSLREKLGFEDATVVKTVRGSELDRVVTKHPFYDRDSLVMNGEHATAEAGTGAVHTAPGHGEDDFLIGKKYDLEVLAPLDDRGVFTEEAPGFEGVFYDTANKMVTEKLEEVGALLKMEFITHSYPHDWRTKKPVIFRATAQWFASIDAFRDDLLAAVKGVNWTPAWGETRLFNMVRDRGDWVISRQRAWGVPLPIFYAENGEAIITDETINHISELFREHGSNVWFERDVKDLLPAGFTHPGSPNGEFTKETDIMDVWFDSGSSHQAVLNARPELSRPADLYMEGSDQYRGWFNSSLTTAVAITGEAPYRNVLSHGFALDGEGRKMSKSLGNTLLPGKVIKQLGADIVRLWVASVDYQADVRVSDEILKQVSEVYRKIRNTMRFLLGNINDFNPTTNAVSYENLREVDKYMLIKLNDLVKNVKDNYEAFEFSTIYHQINNFCTVELSQFYMDFAKDVVYIEAADSHDRRAMQTVFYEAVVTLTKLLAPILPHTTEEVWNSLIGEGVESIHLQDLPEVKVLADSEEITAKWDAFMQIRDNVQKALEFARNEKLIGKSMLAKVTLYVDGEAKTLFDSLEGDFAQLFIVSDFELVEGLENAPESAFKSNQVAVQITVAEGETCERCRVVKKDVGVNPKHPTLCGRCADIVVKHYEA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PFF1_PICST
Sequence: PNGFVKFIRSIFGYRKTSLTLFVILTYVAVLLLAYLDHSLYYSVDLPTSHKEQELLHQAWVDLQHIAKYEHAYGSSGNDYVHDYLESRIVSAVAHKSYVEYDNDLNYTNNIMFGSRSELSGNSFNSVSYYESNNLVVRINGTDETLPALLLSAHFDSVPSSFGVTDDGMGIASLLGVLYYYTGKSTARPRRTIVLNFNNDEEFGLYGATSFLSHPWATGVHYFLNLEGTGAGGKAILFRGTDYGITKYFKGVRYPYGTSIFQQGFNNHLIHSETDYKIYKEKGGLRGLDVAFYKPRDLYHTAGDNIKNIDIKSLWHMLSNALDFTAIVTKGKIDLDADSLDSESSKSNTDTAVYTSFLNFFFAFPTSQVVVASILLLVLIPGISIPFLIIIFGYKKNWELSFVNVTKFPISLAISAALLNLFTNGFIVPFNQFLPNSSPFALVAILFATFLLLNYLILNGINLIFVSYKIVNHDEKLISIIETSFLYWVVLIYSTAKLANNVIGDDHSGEFPIIFLCALQAVASIFGLIGWSFKPVPKEHYVVVPQEEAEPLLGSSDNFNYGSPDVEDDRLVSDGSYDWSIQFLTIVPISTYLIYNSGFLVVDGINKSIQESLISQNLIYKLLQTFAISLSIPLLPFIFKVNRLFVLALFLISTIGVLFVATADSFNVANPLKLRFIQYIDLDKSAQDSFVSVIGREASPLQFVLSDIPSVKDSKGAVACVPTRDGLQDCSYKSSLDPKLVPGAKSFDDYLKVDILKNSSSNVDYPFGLLTGEIRIRVPKNRECVLDFKPSESTKIVSPFKDSPVKTVIVYKGKKSATTKEVEAESIPEGFSKDKDGNYVYKDLVGIDQLQLNKLDWDKSYHVGFQWVPNFSDVDINMKKSATNKLNVSVKCFWAELGKGEESTIPAYEELLHYSPNYVSWANSAKGLVSVSKTVEL
What is the function of this protein?
May be involved in vacuolar sorting and osmoregulation.
What are the official names of this protein?
Vacuolar membrane protease, FXNA-related family protease 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.