PharMolix/UniProtQA huggingface dataset:
Protein: BECN1_YEAST
Sequence: MKCQTCHLPLQLDPSLEGLSLTQRNLLLSNNSIITATNENVISNKGIEAADNCGPQIPKERLRRLGEIQNIKDLNLKDDKLITDSFVFLNHDDDDNANITSNSREDQRYGNANGNDNKKANSDTSDGTSTFRDHDEEEQEATDEDENQQIQLNSKTLSTQVNAMTNVFNILSSQTNIDFPICQDCCNILINRLKSEYDDAIKERDTYAQFLSKLESQNKEISESNKEKQYSHNLSEKENLKKEEERLLDQLLRLEMTDDDLDGELVRLQEKKVQLENEKLQKLSDQNLMDLNNIQFNKNLQSLKLQYELSLNQLDKLRKINIFNATFKISHSGPFATINGLRLGSIPESVVPWKEINAALGQLILLLATINKNLKINLVDYELQPMGSFSKIKKRMVNSVEYNNSTTNAPGDWLILPVYYDENFNLGRIFRKETKFDKSLETTLEIISEITRQLSTIASSYSSQTLTTSQDESSMNNANDVENSTSILELPYIMNKDKINGLSVKLHGSSPNLEWTTAMKFLLTNVKWLLAFSSNLLSKSITLSPTVNYNDKTISGN
What is the function of this protein?
Required for cytoplasm to vacuole transport (Cvt), autophagy, nucleophagy, and mitophagy, as a part of the autophagy-specific VPS34 PI3-kinase complex I.  This complex is essential to recruit the ATG8-phosphatidylinositol conjugate and the ATG12-ATG5 conjugate to the pre-autophagosomal structure.  Also involved in endosome-to-Golgi retrograde transport as part of the VPS34 PI3-kinase complex II.  This second complex is required for the endosome-to-Golgi retrieval of PEP1 and KEX2, and the recruitment of VPS5 and VPS7, two components of the retromer complex, to endosomal membranes (probably through the synthesis of a specific pool of phosphatidylinositol 3-phosphate recruiting the retromer to the endosomes).  Also plays a role in regulation of filamentous growth.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 30, Autophagy-related protein 6.
What is the protein family that this protein belongs to?
Belongs to the beclin family.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein. Preautophagosomal structure membrane; Peripheral membrane protein. Note=With the VPS34 PI3-kinase complex I, localizes to the vacuole-isolation membrane contact site (VICS) during isolation membrane (IM) expansion. The IM is a membrane sac generated from the pre-autophagosomal structure that ultimately expands to become a mature autophagosome.
Protein: HYPA_PARD8
Sequence: MHELSIARSIVELVEEQADNRGASVVEELELEIGHLSGVEIQTLEFALDSAIKGSKLEKARIIRHYIEGEGQCSDCETIFPMNALFSPCPHCGSYLVKILKGKELRVKSIVIKKE
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: SBMC2_DICD3
Sequence: MTLRFDVAPPKKVHCLRVIGPYYQSVPDGFQKLMAWSQEQQLPWTETLAFYWDDPSETEQDQLRADVALVLPEGTAIGENTLGVREETVPGGLFAVLHTIVSNGEFAKAWNELYDLIAQNGYKPARGICFESYLCDGSSGNWEIEIWQSVDPNDGAQ
What is the function of this protein?
Inhibits the supercoiling activity of DNA gyrase.  Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase.  It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell.
What are the official names of this protein?
DNA gyrase inhibitor 2.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PR3C1_MOUSE
Sequence: MQLSLTQARTWKGLFLLVSCMFLWVYVTATRYDRKSNEEIYDNLLSSSRHIHRVAKKMYKILDSKLTEGVCFRNKNTKMCQTISTHSVKKNEDLLKVIINVSNFWTYPLKMLIPAVLTHLDSDDGMMTRAVELNYGNKVVLEGAKALLSRIQPGIEENNEPDRWSDLRELRSSKKSKHLLAFCKFFYCLRKDTKMVTCYLRALKHGKIKTIC
What are the official names of this protein?
Prolactin-3C1, Decidualin, Placental prolactin-like protein J, PLP-J, PRL-like protein J, Prolactin-like protein I, PLP-I, PRL-like protein I.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS28_HYPBU
Sequence: MSQRKEKEFNIIEEIGYPAEVIQIIGRTGVHGEVIQVRVRVLEGRDKGRVLTRNVLGPVRLGDIVILRETEREARRLGRRR
What are the official names of this protein?
30S ribosomal protein S28e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS28 family.
Protein: DHH1_SCHPO
Sequence: MAESLIQKLENANLNDRESFKGQMKAQPVDMRPKTEDVTKTRGTEFEDYYLKRELLMGIFEAGFERPSPIQEESIPIALSGRDILARAKNGTGKTAAFVIPSLEKVDTKKSKIQTLILVPTRELALQTSQVCKTLGKHMNVKVMVTTGGTTLRDDIIRLNDTVHIVVGTPGRVLDLAGKGVADFSECTTFVMDEADKLLSPEFTPIIEQLLSYFPKNRQISLYSATFPLIVKNFMDKHLNKPYEINLMDELTLRGVTQYYAFVDESQKVHCLNTLFSKLQINQSIIFCNSTNRVELLAKKITELGYSCFYSHAKMLQSHRNRVFHNFRNGVCRNLVCSDLLTRGIDIQAVNVVINFDFPKNAETYLHRIGRSGRFGHRGLAISFISWADRFNLYRIENELGTEIQPIPPSIDPSLYVFPNGDYQIPRPLTASADQVLAAQQAKGQEGYHNRPNNNRGGHPRGGGNRGGYRQSNRQPRYRGQQKAD
What is the function of this protein?
ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping.  Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs.  May also have a role in translation and mRNA nuclear export (By similarity).
What are the official names of this protein?
Putative ATP-dependent RNA helicase ste13.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Note=Is concentrated in several cytoplasmic foci called P bodies (or cytoplasmic processing bodies) which represent sites of mRNA decapping and 5' to 3' exonucleotidic decay.
Protein: COAD_MYCSK
Sequence: MSGAVCPGSFDPVTLGHVDIFERAAAQFDEVVVAVLVNPNKKGMFTLDERMEMIAESCAHLPNLRVESGQGLVVDFVRARGYSAIVKGLRSSTDFEYELQMAQMNKHVAGVDTFFIASAPSYSFVSSSLAKEVATLGGDVSALLPDAVNVRLQAKLRG
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_SULDN
Sequence: MIQAFTRLNVADNTGAKEVMCIKVLGGSKRRYAQVGDVIIASVKKATPTAKVKKGKVVKAVIVRTAKEIHRENGSLIRFDDNAAVILDDKREPIGTRIFGPIAREVRYSGFMKIVSLAPEVV
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RL28_METSB
Sequence: MSRRCDLTGKAVQTGNLVSHSNHKTRTRFLPNLCNVTLISDVLQRKVRFRVAVAALRSVEHRGGLDAFLAKADDAELSLGARAIKREILKKQAAAS
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: DBP8_SCLS1
Sequence: MHSKKSIQGSETVEQVSIEAPGSSSPQSNHNSSSDDEQDVQDDISQSDSDSLDSQASRKRRKTSQVLEDGDIPLIATTSVPSRVKAKSQNNLLEPKNFNNGAVLAPTDAQTTFAALDVKPWLVASLGAMAIKRPTGIQKGCIPEILKGRDCIGGSRTGSGKTVAFAVPILQKWAEDPFGIFALVLTPTRELALQIYEQFKAISSPQSLKAVLITGGSDMRPQATALAQRPHVVIATPGRLADHIRTSGEDTVCALRRVRMVVLDEADRLLASGSVGSMLPDVEECLSLLPPPSERQTLLFTATVTPEVRALKDMPRTLGKPPVFVCEVDTQALAIPSSLNQMHLQVPVTHREHYLHMFLLTEKNLPKSIVIFCNRTATADYLTHLLRLLEHRVTALHSKLPQRQRIDNLGRFRASAARILVATDVAARGLDIPEVGLVINYDVPRDPDDYIHRVGRTARAGRKGEAVTFVGQRDVQLILAIEKRVGRQMEAWTEEGVNLETRVIRESLKLVGEKKREAMLEIEEGREVGGKRKRGMKKLS
What is the function of this protein?
ATP-binding RNA helicase involved in 40S ribosomal subunit biogenesis and is required for the normal formation of 18S rRNAs through pre-rRNA processing at A0, A1 and A2 sites.  Required for vegetative growth (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase dbp8.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: GLNB_RHILV
Sequence: MKKIEAIIKPFKLDEVRSPSGVGLQGITVTEAKGFGRQKGHTELYRGAEYVVDFLPKVKVEVVLADENAEAVIEAIRKAAQTGRIGDGKIFVSNVEEVIRIRTGETGIDAI
What is the function of this protein?
In nitrogen-limiting conditions, when the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP.  P-II-UMP allows the deadenylation of glutamine synthetase (GS), thus activating the enzyme.  Conversely, in nitrogen excess P-II is deuridylated and promotes the adenylation of GS.  P-II indirectly controls the transcription of the GS gene (glnA).  P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA.  When P-II is uridylylated to P-II-UMP, these events are reversed.
What are the official names of this protein?
Nitrogen regulatory protein P-II.
What is the protein family that this protein belongs to?
Belongs to the P(II) protein family.
Protein: MON1_KLULA
Sequence: MRRSPSFQISTKNSAKPTTSIDLTNHLSARGGLFYQDIDTGTTASIKAKNDPNLLAATYDHSISADTDLNIDLQSLITSELNSLYPLTLNQETSNKSANTTKFIDERGGKDKHFFVFTSAGKLVFSQWENENHAMGLTGIIHTVMNYFNINDNTAMRQFTMYGKDGIMTRFVFLDKNHIKLMVQCNNNYESTAQLQQQLDLVYSYIISSVSQRNLNKLMLKRSNFDLQHYLTDLDQQLLKSLCESLATQPKLTWFANSLECLPMSPKKRNAINSILSTTYLDFNISNHNGQILYTLVTSLDMRLISILRPSNHTLHTMDLQILFEVVRAQLTDLLLDKVLWFPICFQKFNDNGFLYALIKVLPNNTIMMVISSQKNAFDILNEFVRRIEDKMIDDNTCNNLELQLLDWHKKFPYINHFIYKMKRTVQIYTPSQPTNEMLQFYYHLKNLCEDDKGTNLNKSSVAMLKWKNDATPGLLSGVYWATEKFELYILLNDINLSNQSILKSAKLLIQHIREIESYLFISRGVTF
What is the function of this protein?
In complex with CCZ1, is required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis.  The CCZ1-MON1 complex acts at the fusion of vesicles with the vacuole, through its regulation of the SNARE complex during the coordinated priming and docking stages of fusion, and particularly at the stage of tethering/docking.
What are the official names of this protein?
Vacuolar fusion protein MON1.
What is the protein family that this protein belongs to?
Belongs to the MON1/SAND family.
What are the subcellular locations of this protein?
Endosome, multivesicular body membrane; Peripheral membrane protein. Prevacuolar compartment membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein.
Protein: GPMI_BACLD
Sequence: MSNKLAALIILDGFGLRDETVGNAVAQAKKPNFDRYWNKYPHQTLTASGEAVGLPDGQMGNSEVGHLNIGAGRIVYQSLTRVNVAIREGEFEQNETFLAAMKHVKEKGTNLHLFGLLSDGGVHSHIHHLYALLKLAKKEGVENVYIHGFLDGRDVGPQTAEKYIKELQDQIEEIGVGEIATLSGRYYSMDRDKRWDRVEKAYRAMAYGEGPKYQNPLDVVKDSYENGIYDEFVIPSVITKENGEPVATIKDNDAVIFYNFRPDRAIQISNTFTNDDFRDFDRGDKHPKNLHFVCLTHFSETVDGYVAFKPVNLDNTVGEVLSQNGLKQLRIAETEKYPHVTFFMSGGREEKFPGEERILIDSPKVATYDLKPEMSAYEVKDALVKEIEAEKHNAIILNFANPDMVGHSGKVEPTVKAIEAVDECLGEVVDAILAKGGYAIITADHGNADVLITEEGKPHTAHTTNPVPVIVTKEGVTLREGGILGDLAPTLLDLLGVEKPKEMTGSSLIQK
What is the function of this protein?
Essential for rapid growth and for sporulation.  Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: GKP1A_XENLA
Sequence: MASAVVSMVPTTASRFALLQVDSSSDSDSEKARGAHSSGKAHSGSAARGKNKGNEKKKEKRRKKKEQQQSEANELRNLAFKKIPPKASPGVAVQEHLTHTVPKVAQEEDWQQWQQRDVQLTSDMYEADLEKALILSKLEFEESKDNGNGDNGVPQSKKVNKKDKRKNNQGKDKPLTVPLKDFQLEDKHAKKQEELKSPPLPQDSGFFNKLEEDVTKIILKEKRKEHSTDVTEQFATPEYSMEPVLKDGRTEVLKQEIEKKEVELKQMKSIISQWEAKYREVKARNSQLLKMLQEGEMKDKAEILLQVDELLSIKNELTLQVTTLHAALEQERSKVKILQAEQVKYQGGKKSKRTAELEHGR
What is the function of this protein?
May play a role in the regulation of insulin-dependent IRS1 tyrosine phosphorylation in adipocytes.
What are the official names of this protein?
G kinase-anchoring protein 1-A.
What is the protein family that this protein belongs to?
Belongs to the GKAP1 family.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: MTNB_BOVIN
Sequence: MSGSHAPEGDCCLRQCRAQDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGNEIYIAPSGVQKERIQPEDMFVCDINEKDISGPPPSKNLKKSQCTPLFMNAYTMREAGAVIHTHSKAAVMATLVFPGKEFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKERMARAVNDYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDVAVSMKQAGLDPAQLPAGENGIV
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).  Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation.  May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death.
What are the official names of this protein?
Methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase, APAF1-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_STRR6
Sequence: MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNARTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTRAQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: DAPD_BART1
Sequence: MTHLTQLEIIIEKAFDDRDSINTTTKGEIRESVEHTLSLLDKGEIRVAERQKNGQWYVHQWLKKAVLLSFRLNPMQIITGGINGTHWWDKVPSKFSGWKEDDFQKAGFRSVPGAIVRHSAYVAPNVILMPSFINLGAFVDEGTMVDTWTTVGSCAQIGKHVHLSGGVGIGGVLEPLQANPTIIEDHCFIGARSEVVEGCIIREGAVLGMGVFIGQSTKIIDRTTGEIFIGEVPAYSVVVPGSLPGKPLPNGEAGPNLYCAVIVKRVDQKTREKTSINELLRDETQC
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_RHIEC
Sequence: MRSGVIAQKVGMTRVYNDAGEHVPVTVLRMDGCQVVATRTVEKNGYTAVQLGAGQAKVKNTSKAMRGNFAVANVEPKAKLAEFRVSEDNLLEIGTELKADHFAAGQLVDVTGTTIGKGFAGAMKRHGFGGLRATHGVSVSHRSHGSTGSRQDPGKVFKNKKMAGHMGQTRVTTQNLEVVSTDEDRGLILIKGAVPGSKGAWIIVRDAVKSAAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: HBD_PANTR
Sequence: MVHLTPEEKTAVNALWGKVNVDAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARNFGKEFTPQVQAAYQKVVAGVANALAHKYH
What are the official names of this protein?
Hemoglobin subunit delta, Delta-globin, Hemoglobin delta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RS5_PHOPR
Sequence: MANEKTQSDLNEKLIAVNRVSKTVKGGRIFSFTALTVVGDGNGRIGFGYGKAREVPAAIQKSMEKARRNMVTVALNEGTLHHAVKGRHTGSKVYMQPASEGTGIIAGGAMRAVLEVAGIRNVLAKAYGSTNPINVVRATIAGLSGMNSPEMIAAKRGLSVKEILG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: CSPA_MYCTO
Sequence: MPQGTVKWFNAEKGFGFIAPEDGSADVFVHYTEIQGTGFRTLEENQKVEFEIGHSPKGPQATGVRSL
What are the official names of this protein?
Probable cold shock protein A.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNC_RICBR
Sequence: MESFEELEKLLDYSFKNKALLTEALSHPSLRQHHEYKANKDYERLEFLGDAVLNLIITEILFNNFKEYNEGNLAKIRSYLVCKETICVVGAKLGLKNYIIMTHGEEIAGGRDNPNNIENVTEALIAAIYLDSDITTIHNIIGKLWAEFIKVKDLTDYDPKTALQEWAQSKDHHIPIYRLIKREGVAHLSTFTVSVKINGYEQTGKGHSIKEAEKNAARELLHKLKLL
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YHAM_ECO81
Sequence: MFDSTLNPLWQRYILAVQEEVKPALGCTEPISLALAAAVAAAELEGPVERVEAWVSPNLMKNGLGVTVPGTGMVGLPIAAALGALGGNANAGLEVLKDATAQAISDAKALLAAGKVSVKIQEPCDEILFSRAKVWNGEKWACVTIVGGHTNIVHIETHNGVVFTQQACVTEGEQESPLTVLSRTTLAEILKFVNEVPFAAIRFILDSAKLNCALSQEGLSGNWGLHIGATLEKQCARGLLAKDLSSSIVIRTSAASDARMGGATLPAMSNSGSGNQGITATMPVVVVAEHFGADDERLARALMLSHLSAIYIHNQLPRLSALCAATTAAMGAAAGMAWLVDGRYETISMAISSMIGDVSGMICDGASNSCAMKVSTSASAAWKAVLMALDDTAVTGNEGIVAHDVEQSIANLCALASHSMQQTDRQIIEIMASKAR
What are the official names of this protein?
UPF0597 protein YhaM.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.
Protein: NDK_SULIA
Sequence: MVMQRTFVMIKPDGVKRGLIGEIISRFEKRGLKIVSLKMVKMSRDIAEKLYDEHKGKSFFEELVNYVTSGPVVCMVIEGDDVVQVIRRMIGNTDPKEAPPGTIRGDYALSKSENVIHASDSIEKAQREMSLFFDKSDL
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VE2_HPV63
Sequence: MESLNNRLDWLQEQLLTLYEKDSKDIEDQIMQWNLLRQEQVLFHYARKKGIMRLGLQVVPSLAASQDKAKTAIEMTLYLSGLRDSQYGSEQWSLQDTSREIFLAPPDHTFKKGGQTIEVIYDEDPNNSTRHTVWRHIYYQNGDNRWRKAASDVDVHGVFYLEYDGVKNYYVDFQEEANRYSKTGRYTVQYEGKRFTNVMSPVNSSPLRTSGSPTDTNPATQGQSTQTARKAETKGSRHHPKSPAVRKRRPYGRRRSRSPRDTTLRRGEGESARASAGSGERVAFISPGDVGTSTRSPPKGGQSRLRRLIQEARDPPIICLKGGPNQLKCLRYRIKASNSSDFESISTTWHWVHNKCTDRVGHARMLVRFISTEQRDRFLDKVVVPKSVSVILGAFDGS
What is the function of this protein?
Plays a role in the initiation of viral DNA replication.  A dimer of E2 interacts with a dimer of E1 in order to improve specificity of E1 DNA binding activity.  Once the complex recognizes and binds DNA at specific sites, the E2 dimer is removed from DNA.  E2 also regulates viral transcription through binding to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory regions of the viral genome.  Activates or represses transcription depending on E2RE's position with regards to proximal promoter elements including the TATA-box.  Repression occurs by sterically hindering the assembly of the transcription initiation complex.
What are the official names of this protein?
Regulatory protein E2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E2 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: RS11_MYCBP
Sequence: MPPAKKGPATSARKGQKTRRREKKNVPHGAAHIKSTFNNTIVTITDPQGNVIAWASSGHVGFKGSRKSTPFAAQLAAENAARKAQDHGVRKVDVFVKGPGSGRETAIRSLQAAGLEVGAISDVTPQPHNGVRPPNRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: GC_HHV2G
Sequence: MALGRVGLTVGLWGLLWVGVVVVLANASPGRTITVGPRGNASNAAPSVPRNRSAPRTTPTPPQPRKATKSKASTAKPAPPPKTGPPKTSSEPVRCNRHDPLARYGSRVQIRCRFPNSTRTESRLQIWRYATATDAEIGTAPSLEEVMVNVSAPPGGQLVYDSAPNRTDPHVIWAEGAGPGASPRLYSVVGPLGRQRLIIEELTLETQGMYYWVWGRTDRPSAYGTWVRVRVFRPPSLTIHPHAVLEGQPFKATCTAATYYPGNRAEFVWFEDGRRVFDPAQIHTQTQENPDGFSTVSTVTSAAVGGQGPPRTFTCQLTWHRDSVSFSRRNASGTASVLPRPTITMEFTGDHAVCTAGCVPEGVTFAWFLGDDSSPAEKVAVASQTSCGRPGTATIRSTLPVSYEQTEYICRLAGYPDGIPVLEHHGSHQPPPRDPTERQVIRAVEGAGIGVAVLVAVVLAGTAVVYLTHASSVRYRRLR
What is the function of this protein?
Major attachment protein that mediates binding of the virus to cell surface heparan sulfate or chondroitin sulfate.  Also plays a role in host immune evasion by inhibiting the host complement cascade activation (By similarity).
What are the official names of this protein?
Envelope glycoprotein C, Glycoprotein F.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein C family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass membrane protein.
Protein: SEPF_MICLC
Sequence: MAGALKKTMIYLGLADGDEYDEQPRAAEREAAPRHEVVEARRPAEPDTDPHMEAVRPAAVRDPEPAERPEPVTPSGSTAAEPVEPRRPARPEPVDPGYRAPVTPIKRAAASSAEGASVHTLSTVHPRSYNDAKAIGESFRSGVPVIMNVTDLGENEAKRLVDFAAGLVFGLHGSISRITSKVFLLTPATVDVVGAEQGESSVADSPFDGD
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: PURA_THET2
Sequence: MPGIAIIGAQWGDEGKGKVVDVLAREADYVIRYQGGANAGHTVVAEGKVFKLNLLPSGVIHPHAVNVLGDGMVIDPFRFQEEVEGLRKEGFDPKILVSERAHLVLPHHKHVESRHNFVGTTGRGIGPAYSDRARRVGIRAGDLLDEATLRERVRRLLAEKPNSTREAGWDTEEKALADLHRMREILSPYIADTGSLLREAWRKGKRLLFEGAQATLLDLNYGTYPYVTSSHPTVGGILVGTGLSHKAITKVYGVAKAYTTRVGEGPFPTELQGELAHHLREKGGEYGTTTGRPRRVGWLDLVALRYACEVNGFDGLVLTKLDVLSGLEKVKVAVEYLDGARPGEASPEAVRYLELPGWGDLSHVKRREDLPANLLRYLELVEEHTGVPVVLFSTSPRREDTFGAVSWV
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CWP02_SOLLC
Sequence: EQFDEEFDIT
What are the official names of this protein?
35 kDa cell wall protein.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: AROB_PSEA6
Sequence: MTTLTVKLGERSYPIFIQPSLLTQGNQLADYIKTDKAVLVTNDLVDPLYSQTVIDSLPSIKIEKIVIADGEQHKNLASFEHVITQLLSMSAARDTTLIALGGGVIGDLTGFVAASFQRGMPFIQIPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPKAVFIDTKTLQTLPAKEFSAGMAEVIKYGIIYDKAFFAWLEQNIAQLIAQDVDALQYSIARCCEIKAEIVAIDERESGLRALLNLGHTFGHAIEAEQGYGNWLHGEAVAAGMVLAAKAGQMKGWMSKEEVQRVIALIEAFSLPIAPPANMGYQTFMQHMAHDKKVQAGKLNFIVPKAIGDAVVTSELDETLLRSLLD
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.