PharMolix/UniProtQA huggingface dataset:
Protein: RL5_BIFLD
Sequence: MTDTTVEAPATPRLKVKYNEQIIPELEKEFKYSNPMQVARVQKVVVSMGVGAAARDSKLIEGAVKDLTLITGQKPKITKAKKSVAQFHLREGQAIGAYVTLRGDRMWEFLDRLLTLALPRIRDFRGINGHQFDGQGNYNFGLTEQSMFHEIDPDSIDHVRGMDITVVTSTKDDKEAYALLKHLGFPFKEN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: RS3_PYRFU
Sequence: MAIERYFIREAVREMLIDEFLEKELRRAGYGGLDIKKTPLGTKVIIFAANPGYVIGRGGRRIRELTRILEKQFGLENPQIEVEEIKNPYLNAKVQAVRLAQALERGIHFRRAAYAALRAIMNNGARGVEIRLSGKLTGERAKSIRFYQGYLAKVGNPAETLVSKGYAQALLKLGVIGVKVAIMPPGARLPDEIEIIEKPVEEEVVSNEAE
What is the function of this protein?
Binds the lower part of the 30S subunit head.
What are the official names of this protein?
30S ribosomal protein S3, Small ribosomal subunit protein uS3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: ENV_FLVLB
Sequence: MEGPTHPKPSKDKTFSWDLMILVGVLLRLDVGMANPSPHQIYNVTWTITNLVTGTKANATSMLGTLTDAFPTMYFDLCDIIGNTWNPSDQEPFPGYGCDQPMRRWQQRNTPFYVCPGHANRKQCGGPQDGFCAVWGCETTGETYWRPTSSWDYITVKKGVTQGIYQCSGGGWCGPCYDKAVHSSITGASEGGRCNPLILQFTQKGRQTSWDGPKSWGLRLYRSGYDPIALFSVSRQVMTITLPQAMGPNLVLPDQKPPSRQSQIESRVTPHHSQGNGGTPGITLVNASIAPLSTPVTPASPKRIGTGNRLINLVQGTYLALNVTNPNKTKDCWLCLVSRPPYYEGIAVLGNYSNQTNPPPSCLSDPQHKLTISEVSGQGSCIGTVPKTHQALCKKTQKGHKGTHYLAAPSGTYWACNTGLTPCISMAVLNWTSDFCVLIELWPRVTYHQPEYVYTHFDKTVRLRREPISLTVALMLGGLTVGGIAAGVGTGTKALLETAQFGQLQMAMHTDIQALEESISALEKSLTSLSEVVLQNRRGLDILFLQEGGLCAALKEECCFYADHTGLVRDNMAKLRERLKQRQQLFDSQQGWFEGWFNKSPWFTTLISSIMGPLLILLLILLFGPCILNRLVQFVKDRISVVQALILTQQYQQIKQYDPDQP
What is the function of this protein?
The transmembrane protein (TM) acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm (By similarity).
What are the official names of this protein?
Envelope glycoprotein, Env polyprotein.
What are the subcellular locations of this protein?
[Transmembrane protein]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Surface protein]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM. Both proteins are thought to be concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag (By similarity). SUBCELLULAR LOCATION: [R-peptide]: Host cell membrane; Peripheral membrane protein. Note=The R-peptide is membrane-associated through its palmitate.
Protein: Y388_BLOPB
Sequence: MKYQLLKIIVCPVCHSKLSFDLEKKELICNVDNLAFPIRKGIPVLLKRDARNFIL
What are the official names of this protein?
UPF0434 protein BPEN_388.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: DERPC_HUMAN
Sequence: MKEPRIFPRERPTPWTRAPLPPRGRLDGSLGPQGGPVLNTGHPLGVNSDPFLMAAGSLGGNLTPFPRNPSPFPASSGSLASNPAPFPAGARDPSMASFPRGMNPTGTGAVSFPRPGGLLGPGPGPGPTLNPRTGALPGPGPLSNPRLGGLPGPGPMSNPRAGGLLGAGPDPRGGGPMGPGSGPNLRAGVLLTSGNGPPNPRPVGLGPGPNPNLRSGFLGTNPAPRSGVFPGPGLGPNPRPSGLGPGPNLDARAGGLLGTGSGLNLRMAGPQGLDLAPILRAAGLLGANSASFSQASGNMGTSPSSMARVPGPMGPNSGPSSRGIGLPGPNPSPMSRAPGPIGPNSAHFSRPVGPMGVNANPFPRGAGSSAFSQSSGTLASNPATFQRSAGLQGSNPTIFPRASGPLGPNPANFPRATGLQGPSPTTFPRSTGPLGPGQVTFPRPAAGHLGPSPAGPVGINPAPFTRPTGTLGLNPASFPRMNGPAGKSFVPFPRVGSLPGTNPAAFPRPGGPMAAMYPNGMLPP
What is the function of this protein?
Potential tumor suppressor.  Inhibits prostate tumor cell growth, when overexpressed.
What are the official names of this protein?
Decreased expression in renal and prostate cancer protein.
What is the protein family that this protein belongs to?
Belongs to the DERPC family.
Protein: DHC5A_DANRE
Sequence: MPSGSMSGGVSGPTSPPHPTVPSRPLRPSRYVPVSAATAFLVGSTTLFFCFTCPWLSEQFSVAVPIYNGVMFMFVLANFCMATFMDPGIFPRAEEDEDKEDDFRAPLYKTVEIRGIQVRMKWCSTCRFYRPPRCSHCSVCDNCVEDFDHHCPWVNNCIGRRNYRYFFLFLLSLTAHIMGVFGFGLLFILYHTQQLDRVHSAVTMAVMCVAGLFFIPVAGLTGFHVVLVARGRTTNEQVTGKFRGGVNPFTNGCLRNVSHVLCSSQAPRYLGRKRKAQTVSVQPPFLRPQLTEAQLAAKVLDNGIQGDLHRSKSSLEMMESQSADAEPPPPPKPELRYPGLSRGPAGHSEESSLLNKAPPTPTMFKYRPTYSSPGKNHTALTHAYANQSSQQPGYRSEPSLDGREGGGAERSGAERTGGGPGGPPGSGIPGYSLGGRSYPSFSDPTVLAERASRSSSVRSTHNAPPSEATTSTSYKSLANQTPPQAARNGSLSYDSLLTPSESPDFESAAPEMSPGRPRTPVVGYSSPFLSAQIAHQREAELHQPVASSSALMASPQHAVFLRGSGSPPVPPERERERLLHDSQAQHHHHHHHHHHHHRPPRFSRPPLLSDSGPPQPSYPYRTRSTDTTHPPRSPHPPPLGKSLSYSSAAAAEMQYRLVRKASASVAGGGIQAPKDEIQMKSYSRTNGQPKPSSTPSSPTHPISVSTRPGQAHSSAGSSQSPAHKPGGGVKKVTGVGGTTYEISV
What is the function of this protein?
Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates and is involved in a variety of cellular processes.
What are the official names of this protein?
Palmitoyltransferase ZDHHC5-A, Zinc finger DHHC domain-containing protein 5-A, DHHC-5A.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PDXH_PARXL
Sequence: MTSLAELRKNYSLGSLDVGDVDRNPFRQFDTWFKQAVDAQLPEPNTMTLATVDPRGRPSARIVLIKGVDERGFVFFTNYESRKGRELAANPYASLLFYWIELERQVRVEGRIVKTSAEESDGYFASRPLGSRIGAWASNQSQVIESRSQLETREREFSLLYGDQPPRPPHWGGYRLVPEAIEFWQGRPSRLHDRLLYTRSDEHSDWQISRLSP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: THII_OCEIH
Sequence: MNYDHILIRYGEMALKGKNIKQFIIKLQENIQQKIKHFEGVKVKRTQGRMFVLLNGNEPEPIIEKLKNVFGIHSLSIAIRVENTEEQIKEGALYALKREANAKTFKVTVKRISKDFPIPSQQMNQILGGHLLANTNDITVNVHEPDVEVRVEIRKEATYITSGTIRCRGGLPVGTSGKSLLLLSGGIDSPVAGFLAMKRGVQLEAIHFHSPPFTSERAKQKVLDLTQTLTKYGKSIKVHIVPFTKLQQEIFREMPNDYAMTIMRRMMFRISERICEQEEILSLTTGENLGQVASQTMQSMHTINEVTNYPIIRPLISMDKQEVIEVSQEIGTYETSIQPYEDCCTIFVPKSPKTKPKREKVNYYESHHDFTPTMEETINGIETVKITDKTVIDQSFKDLL
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GH310_ARATH
Sequence: METVEAGHDDVIGWFEHVSENACKVQSETLRRILELNSGVEYLRKWLGTVDVEKMDDYTLETLFTSLVPIVSHADLDPYIQRIADGETSPLLTQEPITVLSLSSGTTEGRQKYVPFTRHSAQTTLQIFRLSAAYRSRFYPIREGGRILEFIYAGKEFKTLGGLTVGTATTHYYASEEFKTKQETTKSFTCSPQEVISGGDFGQCTYCHLLLGLHYSSQVEFVASAFSYTIVQAFSFFEEIWREICADIKEGNLSSRITLPKMRKAVLALIRPNPSLASHIEEICLELETNLGWFGLISKLWPNAKFISSIMTGSMLPYLNKLRHYAGGLPLVSADYGSTESWIGVNVDPHLPPEDVSFAVIPTFSYFEFIPLYRRQNQSDICIDGDFVEDKPVPLSQVKLGQEYELVLTTFTGLYRYRLGDVVEVTSFHKGTPKLSFIYRRKLILTINIDKNTEKDLQRVVDKASQLLSRSTRAEVVDFTSHADVIARPGHYVIYWEIRGEADDKALEECCREMDTAFVDYGYVVSRRMNSIGPLELRVVERGTFGKVAERCVGKCGGLNQFKTPRCTTNSVMLDILNDSTIKRFRSSAYD
What is the function of this protein?
Catalyzes the synthesis of indole-3-acetic acid (IAA)-amino acid conjugates, providing a mechanism for the plant to cope with the presence of excess auxin (By similarity).  Involved in red light-specific hypocotyl elongation.  May act downstream of a red light signal transduction and determine the degree of hypocotyl elongation (PubMed:14581632).
What are the official names of this protein?
Indole-3-acetic acid-amido synthetase GH3.10, Auxin-responsive GH3-like protein 10, Protein DWARF IN LIGHT 2.
What is the protein family that this protein belongs to?
Belongs to the IAA-amido conjugating enzyme family.
Protein: ULAD_SHIDS
Sequence: MSLPMLQVALDNQTMDSAYETTRLIAEEVDIIEVGTILCVGEGVRAVRDLKALYPHKIVLADAKIADAGKILSRMCFEANADWVTVICCADINTAKGALDVAKEFNGDVQIELTGYWTWEQAQQWRDAGIGQVVYHRSRDAQAAGVAWGGADITAIKRLSDMGFKVTVTGGLALEDLPLFKGIPIHVFIAGRSIRDAASPVEAARQFKRSIAELWG
What is the function of this protein?
Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P.  Is involved in the anaerobic L-ascorbate utilization.
What are the official names of this protein?
3-keto-L-gulonate-6-phosphate decarboxylase UlaD, 3-dehydro-L-gulonate-6-phosphate decarboxylase, KGPDC, L-ascorbate utilization protein D.
What is the protein family that this protein belongs to?
Belongs to the HPS/KGPDC family. KGPDC subfamily.
Protein: ACS2_ASHGO
Sequence: MSCKEHKVVHEAHNVEARKTPDHFYRSQPGPSYVQDIEQYRTMYQQSIEDPDAFFGEKAREFLHWEKDFTHVRAGSLRTGDTAWFLNGELNAAYNCVDRHALENPDKVAIIYEADDEADNRVVTFGELLRQVSQVAGVLQSWGVKKGDTVAVYMPMIPEAVVAMLAVARLGAVHSVIFAGFSSGSLRDRIVDAESKVVITCDEGRRGGKTVHTKKIVDEGLAGVGVVSHILVFQRTGSEGIPMKAGRDFWWHEEVRKQRGYLPPVSVNAEDPIFLLYTSGSTGSPKGVVHTTGGYLLGAALTTRYVFDIHPEDVLFTAGDVGWITGHTYALYGPLCLGTATIIFESTPAYPDYGRYWRIIQRHKATHFYVAPTAMRLIKTVGEQEISKYDLSSLRVLGSVGEPIAPDLWEWYNEKVGNNNCVVCDTMWQTESGSHLIAPLAGAIPTKPGSATVPFFGINACIIDPVTGDELEGNDVEGVLAIKSPWPSMARSVWNNHDRYIETYLKPYPGYYFTGDGAGRDHDGYYWIRGRVDDVVNVSGHRLSTAEIEAALSEHEGVSQAAVVGIADELTGQAVVAFVSLKEGYGRGSSTDTDPESIAPDVVPLDTLRRELVLQVRAEIGPFAAPKSVIVVDDLPKTRSGKIMRRTLRKISANEADQLGDLSTLANPETVPAIIAAVGAQFLKGKK
What are the official names of this protein?
Acetyl-coenzyme A synthetase 2, Acetate--CoA ligase 2, Acyl-activating enzyme 2.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: DXO_USTMA
Sequence: MPDKRALSDSYEQLPLKRAATVSSNTNDISDERIIATLRHPRACVSASGSPFSASPSFQQPVPLCSFSFDEHRKQWHDDRCKRFYRGPPPYNQRHPRQHGARAVFGADLNYGLERFVRRDQDVPEHLDALVAALQHRTEAAVSDEERDQVDQERRKADVVTWRGIITKICTAYEQTAEARFSDPLELNAMMLDDTLYLEEYTCKSARAQKQNKEDDPKMLRMGYYGYSFESYCTVDTELQTREPFRPIPSKESSLPHPAGWSGDVNTNVQWCQVVKTKLGNNRLVIGGEVDAVERNPKTGREELVELKTSMQMTWAQHNPSKAALDQERFEKKLLKFFLQSYLLGIGKIVVGFRDHHGILTTHQDFETLRIPRMVRAGQPIAGRFDHTGKPVIRQQSVWEPKDGLGFGDQILSFIRQTILSRSIQATPTEQISAGAGANTPNPTAAVGQVHHPVYRVTFRSPFDQVEMRCLSEQEIYEEVQDSGGSGARVGFLPRSFYDFVQRRAGS
What is the function of this protein?
Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA (By similarity).  The NAD-cap is present at the 5'-end of some RNAs and snoRNAs.  In contrast to the canonical 5'-end N7 methylguanosine (m7G) cap, the NAD cap promotes mRNA decay (By similarity).  Also acts as a non-canonical decapping enzyme that removes the entire cap structure of m7G capped or incompletely capped RNAs (By similarity).  Has decapping activity toward incomplete 5'-end m7G cap mRNAs such as unmethylated 5'-end-capped RNA (cap0), while it has no activity toward 2'-O-ribose methylated m7G cap (cap1) (By similarity).
What are the official names of this protein?
Decapping nuclease RAI1, NAD-capped RNA hydrolase RAI1, DeNADding enzyme RAI1.
What is the protein family that this protein belongs to?
Belongs to the DXO/Dom3Z family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RECF_XANC5
Sequence: MHVVRLSIHRLRRFHTVELHPSSTLNLLTGDNGAGKTSVLEALHLMAYGRSFRGRVRDGLIQQGANDLEVFVEWKEGNGAAGERTRRAGLRHRGQEWTGRLDGEDVAQLGALCAALAVVTFEPGSHVLISGGGEPRRRFLDWGLFHVEPDFLTMWRRYARALKQRNALLKQGAQPRMLDAWDHELAESGESLTSRRTRYLERLQERLVPVADAIAPALGLSALTFAPGWKRHEVSLADALLLARERDRQNGYTSQGPHRADWVPSFQALPGRDALSRGQAKLTALACLLAQAEDFAYERGEWPVIALDDLGSELDRHHQGRVLQRLASAPAQVLITATETPPGLADAGALLQQFHVEHGHITRQAAAH
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACP_DICNV
Sequence: MSNIEERVIKVIAEQLNVDEGQVKADAHFIDDLGADSLDLVELVMTLEKEFDCEIPDEEAEKITTVQSAIDFVKSR
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IHFA_NEIMF
Sequence: MTLTKAELADILVDKVSNVTKNDAKEIVELFFEEIRSTLASGEEIKISGFGNFQLRDKPQRPGRNPKTGEEVPITARRVVTFHASQKLKSMVEHYYDKQR
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: NUOCD_SHIDS
Sequence: MVNNMTDLTAQEPAWQTRDHLDDPVIGELRNRFGPDAFTVQATRTGVPVVWIKREQLLEVGDFLKKLPKPYVMLFDLHGMDERLRTHREGLPAADFSVFYHLISIDRNRDIMLKVALAENDLHVPTFTKLFPNANWYERETWDLFGITFDGHPNLRRIMMPQTWKGHPLRKDYPARATEFSPFELTKAKQDLEMEALTFKPEEWGMKRGTENEDFMFLNLGPNHPSAHGAFRIVLQLDGEEIVDCVPDIGYHHRGAEKMGERQSWHSYIPYTDRIEYLGGCVNEMPYVLAVEKLAGITVPDRVNVIRVMLSELFRINSHLLYISTFIQDVGAMTPVFFAFTDRQKIYDLVEAITGFRMHPAWFRIGGVAHDLPRGWDRLLREFLDWMPKRLASYEKAALQNTILKGRSQGVAAYGAKEALEWGTTGAGLRATGIDFDVRKARPYSGYENFDFEIPVGGGVSDCYTRVMLKVEELRQSLRILEQCLNNMPEGPFKADHPLTTPPPKERTLQHIETLITHFLQVSWGPVMPANESFQMIEATKGINSYYLTSDGSTMSYRTRIRTPSYAHLQQIPAAIRGSLVSDLIVYLGSIDFVMSDVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RSGA_XYLFA
Sequence: MIEPVVGYRMLQAIGWPWPGPPADAAWQAMCAVYSQCRPARVIEQHRSGYVVAEAPEVPIKVESLPAWQRRGFPRHERAVVGDWVLLDGRRIVALLPRRTVIKRLAAGEHYRQQLIAANLDTAFIVCGLDGDFNPRRIERYCVLIGSGGVEPVVVLTKVDLCADVGAAVAVLREHSSQALAVVAVDAREAEPVAALYPWLLPGRTVALLGSSGAGKSTLTNTLLGEQRMKVGEVRQRDSRGRHTTTHRALLPLPSGACLIDTPGMRELKFTGEEDLVEEFADIELLATQCRFRDCAHQAEPGCAVRAAIGCGTLDPQRLHHYFKLRGEIVGAADRSTLRRY
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPF1_XENLA
Sequence: MAEKKGPEAKKQKKMKNKSKVEETDAGEEAGASEEQQQVTRLPPAFSLSEIKNKQRRQFMFIKLKQEKRKEKLILRKKRKKEREALGDKAPPKPVPKTIENQRVYDETTVDPADEEVALDEATDEFAPYFNKQTTPKILITTSDRPRGRSVRFTEQLSSIIPNSDVYYRRGLALKKIIPQCVSRDYTDLLVINEDRKVPNGLVLCHLPDGPTAHFKISNVRLRKEMKRKGKEPTEHKPEVILNNFTTRLGHSIGRMFASLYPHDPHFVGRQVATFHNQRDYIFFRYHRYLFKSEKKVGIQELGPRFTLKLRSLQKGTFDSKYGEYEWVHKRHEMDTSRRKFHL
What is the function of this protein?
May be required for ribosome biogenesis.
What are the official names of this protein?
Ribosome production factor 1, Brix domain-containing protein 5, Ribosome biogenesis protein RPF1.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: MENG_THET2
Sequence: MFSEIAPRYDLLNRLLSFGADLRWRRRAVDLALEKAPKRILDLATGTGDLALMLKERAPGAEVVGADFAPPMLAIARRKAEARGLEVRFLEADALALPFPDGAFDAVTIAFGFRNFADYEKALGELYRVLAPGGRLVVLEFPPPPKGAFGLVYRVYFQRVLPFLGGLISGNFGAYRYLPESVEAFPAPEALKAMMAAAGFSVRYELLTFGVAAIHVGDRP
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
What are the official names of this protein?
Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: FKB15_VICFA
Sequence: MKLFSIFLIFTIFIIASALVAAKSAADVTELQIGVKYKPASCEVQAHKGDKVKVHYRGKLTDGTVFDSSFERNSPIDFELGGGQVIKGWDQGLLGMCLGEKRKLKIPAKLGYGEQGSPPTIPGGATLIFDTELVGVNDKSLSEEKSTSSEL
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
What are the official names of this protein?
FK506-binding protein 2, 15 kDa FKBP, FKBP-15, Peptidyl-prolyl cis-trans isomerase, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. FKBP2 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: HFE_PANTR
Sequence: MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE
What is the function of this protein?
Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin.
What are the official names of this protein?
Hereditary hemochromatosis protein homolog.
What is the protein family that this protein belongs to?
Belongs to the MHC class I family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: MINY2_BOVIN
Sequence: MESGPESLQPLEHGVAAGPAPGTGSPQEGQQETRLAAGDGPGVWAAESSGGKGQGAAAGGRSLSDSASPAGSPQVLVPCSSLPRLDLKESDLESPAAQKEPVRGQHKVTASPETAEAGADHGLGPEGDGGARPDPAGTCQEESAAAGSSEPSSGGGLSSSCSDPSPPGESPSLDSLESFSNLHSFPSSSEFNSEEGAENRVPEEEEGAAVLPGAVPLCGEEEVEEEEAQVLAASKERFPGQSVYHIKWIQWKEENTPIITQNENGPCPLLAILNVLLLAWKVKLPPMMEIITAEQLMEYLGDYMLDTKPKEISEIQRLNYEQNMSDAMAVLHKLQTGLDVNVKFTGVRVFEYTPECIVFDLLDIPLYHGWLVDPQIDDIVKAVGNCSYNQLVEKIISCKQSENSELVSEGFVAEQFLNNTATQLTYHGLCELTSTVQEGELCVFFRNNHFSTMTKYKGLLYLLVTDQGFLTEEKVVWESLHNVDGDGNFCDSEFHLRPPSDPETVYRGQQDQIDQDYLMALSLQQEQQSQEINWEQIPEGISDLELAKKLQEEEDRRASQYYQEQEQAAAAAASASASASASASTQAPQSQPVQASPSSGRQSGNSERKRKEPREKDKEKEKEKNSCVIL
What is the function of this protein?
Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.  Can also bind to polyubiquitin chains of different linkage types, including 'Lys-6', 'Lys-11', 'Lys-29', 'Lys-33' and 'Lys-63'.  May play a regulatory role at the level of protein turnover.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase MINDY-2, Deubiquitinating enzyme MINDY-2, Protein FAM63B.
What is the protein family that this protein belongs to?
Belongs to the MINDY deubiquitinase family. FAM63 subfamily.
Protein: BCSA_ECOLI
Sequence: MSILTRWLLIPPVNARLIGRYRDYRRHGASAFSATLGCFWMILAWIFIPLEHPRWQRIRAEHKNLYPHINASRPRPLDPVRYLIQTCWLLIGASRKETPKPRRRAFSGLQNIRGRYHQWMNELPERVSHKTQHLDEKKELGHLSAGARRLILGIIVTFSLILALICVTQPFNPLAQFIFLMLLWGVALIVRRMPGRFSALMLIVLSLTVSCRYIWWRYTSTLNWDDPVSLVCGLILLFAETYAWIVLVLGYFQVVWPLNRQPVPLPKDMSLWPSVDIFVPTYNEDLNVVKNTIYASLGIDWPKDKLNIWILDDGGREEFRQFAQNVGVKYIARTTHEHAKAGNINNALKYAKGEFVSIFDCDHVPTRSFLQMTMGWFLKEKQLAMMQTPHHFFSPDPFERNLGRFRKTPNEGTLFYGLVQDGNDMWDATFFCGSCAVIRRKPLDEIGGIAVETVTEDAHTSLRLHRRGYTSAYMRIPQAAGLATESLSAHIGQRIRWARGMVQIFRLDNPLTGKGLKFAQRLCYVNAMFHFLSGIPRLIFLTAPLAFLLLHAYIIYAPALMIALFVLPHMIHASLTNSKIQGKYRHSFWSEIYETVLAWYIAPPTLVALINPHKGKFNVTAKGGLVEEEYVDWVISRPYIFLVLLNLVGVAVGIWRYFYGPPTEMLTVVVSMVWVFYNLIVLGGAVAVSVESKQVRRSHRVEMTMPAAIAREDGHLFSCTVQDFSDGGLGIKINGQAQILEGQKVNLLLKRGQQEYVFPTQVARVMGNEVGLKLMPLTTQQHIDFVQCTFARADTWALWQDSYPEDKPLESLLDILKLGFRGYRHLAEFAPSSVKGIFRVLTSLVSWVVSFIPRRPERSETAQPSDQALAQQ
What is the function of this protein?
Catalytic subunit of cellulose synthase.  It polymerizes uridine 5'-diphosphate glucose to cellulose, which is produced as an extracellular component for mechanical and chemical protection at the onset of the stationary phase, when the cells exhibit multicellular behavior (rdar morphotype).  Coexpression of cellulose and thin aggregative fimbriae (curli fimbrae or fibers) leads to a hydrophobic network with tightly packed cells embedded in a highly inert matrix that confers cohesion, elasticity and tissue-like properties to colonies (PubMed:24097954).
What are the official names of this protein?
Cellulose synthase catalytic subunit [UDP-forming].
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUF2_MOUSE
Sequence: METLSFPRYNVAELVVHIRNKLLTGADGKNLSKSDFLPNPKSDVLYMIYMKALQLVYGVRLEHFYMMPMNIEVTYPHLMEGFLPVRSLFFYMDSFMPICRVNDFEIVDILNPRTNRTSRFLSGIINFIHFRETCLEKCEEFLLQNKSSMVRMQQLSNVHQEALMKLEKLNTVPAEEREEFKQFMDDIQELQHLLNEEFRQKTTLLQEEYAKMKSDISEKTKHLNEQKLSLVSLKEVEDNLKSKIVDSPEKLKNYKDKMKGTVQKLRSAREKVMEQYDIYRDSVDCLPSCQLEVQLYQKKSQDLADNREKLSSLLKESLNLEDQIESDSSELKKLKTEENSLIRMTTVKKEKLATARFKINKKQEDVKHYKQAMIEDCNKVQEKRDAVCEQVTTVNQEIHKIKSAIQQLRDTKKREILKSQEIFVNLKSALEKYHEGIEKVAEERSAKLEEKTAELKKRMVRMV
What is the function of this protein?
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.  Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.  The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules.
What are the official names of this protein?
Kinetochore protein Nuf2, Cell division cycle-associated protein 1.
What is the protein family that this protein belongs to?
Belongs to the NUF2 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Localizes to kinetochores from late prophase to anaphase. Localizes specifically to the outer plate of the kinetochore (By similarity).
Protein: Y6069_BURO0
Sequence: MLRYAIIFFIIAIIAAVFGFGGIAAGAAEIAKILFYIFVVIFLVTLLLGVVRR
What are the official names of this protein?
UPF0391 membrane protein Bcenmc03_6069.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.