PharMolix/UniProtQA huggingface dataset:
Protein: QUEC_XYLF2
Sequence: MKKAVILLSGGMDSAVVTAIAQSQGFMVHALSIRYGQRHTSELDAAVRIARALNVVAHKVVDVDLRSIGGSALTDDIEIPDAGGEGIPVTYVPARNTIMLSLALGWAEVIGAADIFCGVNAVDYSGYPDCRPQFITAFETLANLATKVGVEGTQLHVHAPLQFLSKAEIVHEGLLHGVDFGLTVSCYRADVDGRACGRCDACKLRVAGFADAGVVDPTRYMELPCSLLLL
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: Y2795_BURCH
Sequence: MRIVLITGISGSGKSVALNALEDAGYYCVDNLPPHVLPELARYLAQDGQRRLAVAIDARSSASLDEMPGLIRELSREHDVRVLFLNASTQALIQRFSETRRRHPLSGSRSHDADVGLLSSLEEAIERERELVAPLAEFGHQIDTSTLRANALRTWVKRFIEQKNNDLMVMFESFGFKRGVPLDADLMFDVRALPNPYYDHQLRPLTGLDQPVIAFLDALPIVHQMIDDIHAFLMKWLPHFRDDNRSYLTVAIGCTGGQHRSVFIAETLAARLARDANVIVRHRDAPVDVDASSRLVSEVDRP
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Bcen2424_2795.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: MOAC_GEOUR
Sequence: MSFNHFDEQGQAIMVDVSGKEPTLRTARAQAVVRLRPETLQAILDGRMTKGDVLGVARLAGIAAAKKTPELIPLSHPLAIHHAAVEFATDPETGEIAVTATVRAFERTGVEMEAMVSASVAALTVYDMCKGSDKGITIGQVALLYKEGGKSGVYRREEER
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: RRAAH_XANCB
Sequence: MTWTTPDLCDRFPEVAVAEPLFRHFGGRTTFSGPIATVRCVEDNSRIRELASTPGDGRVLVVDGQGSLRHALFGDQIGAQAVANGWAGVLIHGCVRDVEILAGLPLGVLALAACPRRTERRDLGDVDVPVNFAGVAFVPGHWLYADANGVVVAAAPLSLEVVGMEH
What is the function of this protein?
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.  Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
What are the official names of this protein?
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase, HMG aldolase, Oxaloacetate decarboxylase, OAA decarboxylase, Regulator of ribonuclease activity homolog, RraA-like protein.
What is the protein family that this protein belongs to?
Belongs to the class II aldolase/RraA-like family.
Protein: ACDB_BACSU
Sequence: MHVTQEQVMMRKMVRDFARKEIAPAAEIMEKTDEFPFQLIKKMGKHGLMGIPVPEQYGGAGADVVSYILAIHEISRISAAVGVILSVHTSVGTNPILYFGNEEQKMKYIPNLASGDHLGAFALTEPHSGSDAGSLRTTAIKKNGKYLLNGSKIFITNGGAADIYITFALTAPDQGRHGISAFIVEKNTPGFTVGKKERKLGLYGSNTTELIFDNAEVPEANLLGKEGDGFHIAMANLNVGRIGIAAQALGIAEAALEHAVDYAKQRVQFGRPIAANQGISFKLADMATRAEAARHLVYHAADLHNRGLNCGKEASMAKQFASDAAVKAALDAVQIYGGYGYMKDYPVERLLRDAKVTQIYEGTNEIQRLIISKYLLGGT
What are the official names of this protein?
Acyl-CoA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
Protein: RIBB_ECO27
Sequence: MNQTLLSSFGTPFERVENALAALREGRGVMVLDDEDRENEGDMIFPAETMTVEQMALTIRHGSGIVCLCITDDRRKQLDLPMMVENNTSAYGTGFTVTIEAAEGVTTGVSAADRITTVRAAIADGAKPSDLNRPGHVFPLRAQAGGVLTRGGHTEATIDLMTLAGFKPAGVLCELTNDDGTMARAPECIEFANKHNMALVTIEDLVAYRQAHERKAS
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: VM2B_TRIGA
Sequence: EAGKDCDCGSPANPCCDAATCKLLPGAQCGEGPCCDQCSFMKKGTICRRARGDDLDDYCNGRSAGCPRNPFHA
What is the function of this protein?
Inhibits fibrinogen interaction with platelets.  Acts by binding to the alpha-IIb/beta-3 receptor (ITGA2B/ITGB3) on the platelet surface and inhibits aggregation induced by ADP, thrombin, platelet-activating factor and collagen.
What are the official names of this protein?
Disintegrin trigramin-beta-2, Platelet aggregation activation inhibitor.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-II subfamily. P-IIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SRP_CHLMU
Sequence: MSTTPIVSGVTSQNNSSENVSNNARSLTLKERASKILSSTAFKVGLAVVGIFLVILSIVLLFILPATAASNPIYLAIPAILGCVNICIGILSMNKGSCSEAKWKLCKNVLKTSEDILDDGELNNSNKIFTDDNLSRVEDIVITLSSRRNSVA
What are the official names of this protein?
Sulfur-rich protein, Cysteine-rich protein A.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PTMA_HALH5
Sequence: MSQTILSTETIKVKAEARSKEEAIKAAGTLLVEKGYVEPNYVDKMFERETVTSTYLGNYLAIPHGTEEAKEQVIHSGMSVLVFDDPVDWDGQEVRVVIGIAGKGTEHLDILSKIAITFSEEENVERLLSLESAQEVLAFLGEVNE
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II CmtAB PTS system is involved in D-mannitol transport.
What are the official names of this protein?
Mannitol-specific phosphotransferase enzyme IIA component, EIIA, EIII, PTS system mannitol-specific EIIA component.
Protein: RL35_RICPU
Sequence: MPKLKTKSAVKKRFKLTASGKVIASQAGKKHFMRRRTKAQIRNLRGTTILCPQDGYNIKKYFLPYGIN
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: MSRQ_BRUA1
Sequence: MAAATGTRKKKTPRPGQWKLWLLYTAGFVPAVWTFYLGATGQLGADPVKTFEHLLGLWALRFLILTLLVTPIRDLTGITLLRYRRALGLLAFYYALMHFTTYMVLDQGLNLSAIITDIVRRPFITIGMISLALLVPLALTSNNWSIRKLGRRWSSLHKLVYIAIAGSAVHFLMSVKSWPAEPVIYAAIVAALLLWRLARPYLRTRKPALRPRGEAIALRK
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation.  MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ, Flavocytochrome MsrQ.
What is the protein family that this protein belongs to?
Belongs to the MsrQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RF1_OLEA2
Sequence: MFAKLEHLERQFEDLEQQLSSPEVFGDQERYRKLTKAHSDLKEIVEVFRVYRQLNEELAGNKEMLRDSDPEIQAMAREEIDAIEKRLPEMEHELKLLLLPKDPLDEKNVVLEIRAGTGGEEAALFAADLFRMYLRYAEDMGWRVEVLSSSETDSGGFKEIIGLISGDKVYSRMKFESGTHRVQRVPATETQGRIHTSAATVAVMPEADEVELDMKPEDLRFDVYRSSGPGGQSVNTTDSAVRVTHIPTGITVACQDEKSQHKNKAKGLKILASRLLQAQEDKRHEELAEQRRSLVGTGDRSGRIRTYNFPQGRITDHRINLTLYKLDAFMEGQIGDMLDALITHAQTEALKAQANVH
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPIB_ARTBE
Sequence: MARIGRILTLVVFAAVGLFLFMGQTVEAKGPKITSKVYFDIEHDGQPLGRIVMGLYGKTVPKTAENFRALATGEKGFGYEGSTFHRVIKDFMIQGGDFTNGDGTGGKSIYGNKFEDENFKLRHTKKGVLSMANAGKDTNGSQFFITTAITAWLDGKHVVFGEVLEGYDIVDKIQVVPKGFQDRPTKDVKIVKCGELDMKEEAEGEGTESPSKPDSEKEQAPVRDEI
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase B, PPIase B, Rotamase B.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase B subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: Y019_BORBU
Sequence: MFIVSLLLLFSVLNVYSNSLDYFKSNFNYLKLSDAKSLPLQDKSTSSGNFVSHKKNNNMSVADNDDSFLYKNIQENKALNLENDLESKSAKDFFRFSAISIGSFPIVLFLSLFFFDVSYYFYSGMNANYVPYPFSNGPSFSKDEIYKKFIVSASIGAIVALTIALLDYFL
What are the official names of this protein?
Uncharacterized protein BB_0019.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: WTR3_ARATH
Sequence: MGEDMRGVKVVSKWPPMIVMVTSQVAMGSVNALVKKALDVGVNHMIIGAYRMAISSFILVPIAYFLERKIIPKITFRLMVDHFISGLLGASLMQFFYLLGLSYTSATVACALVSLMPAITFAFALILRTEKIKDLKTQAGMIKVMGTLICISGALFLTFYKGPHISNSHSHLEALPHNNSDHNTKNWLLGCLYLVIGIVLLSLWILFQGTLSIKYPCKFSSTCLMSIFAAFQCALLSLYKSRDLKHWIIDDGFVIGVIIYAGVIGQAMSTVAATWGINRLGAVFASAIMPVSLISATLFDFLILHTPLYLGSVIGSVGTIIGLYVFLWGKNKETEADITTLSSRMNNEDQRV
What are the official names of this protein?
WAT1-related protein At1g11450.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Plant drug/metabolite exporter (P-DME) (TC 2.A.7.4) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS14_BLOFL
Sequence: MPRKSVQEREKKRLRLINKYFLRRSLLRKCVVDLKVSSEERWNAVLKLQTLPRDSSPSRLRNRCGRTGRPHAFLRKFGLSRMKVREAAMKGEIPGLRKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: GLTB_PORPU
Sequence: MFNQKIIEQASGKLTGSLTKSSSLVSIEKERDACGVGFIADVNNIANHKIVVQALEALTCMEHRGACSADRDSGDGAGITTAIPWNLFQSGLKDKGIIIQKNESIGVGMLFLPTSKLQESKKIIENVLKEENLEVVGWRLVPTVEEVLGKQAYLNKPHVEQMFCRSSNLSKNELEQQLFLVRKKIERYIGINGKEWAHEFYVCSLSCYTIVYKGMMRSAVLGQFYQDLYHSEYTSSFAIYHRRFSTNTMPKWPLAQPMRFISHNGEINTLLGNLNWMRSREPLLKSPIWKNRIDELKPITNKDNSDSANLDAAVELLIASGRSAEEALMILVPEAFQNQPEFNKNTEISDFYEYYSGLQEPWDGPALVVFTDGKVIGATLDRNGLRPARYVITKDNLVIVSSESGVVQVEPSNIKSKGRLGPGQMISVDIISHKILNNKEIKTSVAGKTPYGDLLKESRQILGHQAFFSEQQVESKKLMQLQTAFGYTNEDVELVIEHMASQGKEPTFCMGDDIPLAILSEKSHILYDYFKQRFAQVTNPAIDPLRESLVMSLTIQIGHKSNLLDDQPVLAKHIKLDSPIINEGELNAILESKLSCAHINTIFKVEKGPNDFKKQIEQLCESASQAILSGNNILILSDKNDILESEKVSIPPLLAAGAVHHHLINKGLRQDASIIIETAQCWSTHHFACLIGYGASAICPYLAFETARHWWSNPKTKMLMSKGRLPACNIQEAQANYKKAVEAGLLKILSKMGISLLSSYHGAQIFEILGLGSEVVNFAFKGTTSQIGGLSMEELGQETVNIHSKAFSQVKTKKLANYGFVQYRPGGEYHINNPEMSKALHQAVRGYNPEYYNSYQRLLQNRPPTALRDLLKLKSNKQPIAIDKVESMENILHKFCTGGMSLGALSRETHETLAIAMNRIGGKSNSGEGGEDPVRFKVLNDVNESGNSDLLPHLKGLRNGDTASSAIKQIASGRFGVTPEYLMNAKQLEIKIAQGAKPGEGGQLPGKKISPYIATLRKCKPGVPLISPPPHHDIYSIEDLSQLIFDLHQINPTAKISVKLVSEIGIGTIAAGVAKGNADIIQISGHDGGTGASPLSSIKHAGSPWELGLSEVHQLLAENQLRDRVTLRVDGGLRTGSDIVLAAIMGAEEFGFGTIAMIATGCIMARICHTNKCPVGVATQREELRARFSGVPEALVNFFLFIGNEVREILASLGYKSLDEITGQNHLLIKNTDIELAKTRGIELNSLININTHTWTKFNSVHTNGPVMDDDILAIPEINDAIKLENEVAKHFKIANTNRTVGTRLSGVIAQKYGNEGFKGLIKLNFYGSAGQSFGAFLASGVNLKLMGEANDYVGKGMNGGSIIIVPPAGTTYEDNNQVIIGNTCLYGATGGYLFAQGQAGERFAVRNSLAKSVVEGVGDHACEYMTGGTIVVLGKAGRNVGAGMTGGLAYFLDEENKFIERVNSEIVKVQRVITKAGEQQLKNLIENHSAKTGSLKAHNILENWNTYLPQFWQVVPPSEANIEETNTAYSSNTITAY
What are the official names of this protein?
Ferredoxin-dependent glutamate synthase, Fd-GOGAT.
What is the protein family that this protein belongs to?
Belongs to the glutamate synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: HSBH1_SOYBN
Sequence: MEGGSSSSNGTSYLLAFGENNSGGLCPMTMMPLVTSHHAGHHPINPSNNNNVNTNCLFIPNCSNSTGTPSIMLHNNHNNNKTDDDDNNNNTGLGYYFMESDHHHHHHGNNNNNGSSSSSSSSAVKAKIMAHPHYHRLLAAYVNCQKVGAPPEVVARLEEACASAATMAGGDAAAGSSCIGEDPALDQFMEAYCEMLTKYEQELSKPLKEAMLFLQRIECQFKNLTISSSDFASNEGGDRNGSSEEDVDLHNMIDPQAEDRDLKGQLLRKYSGYLGSLKQEFMKKRKKGKLPKEARQQLLEWWNRHYKWPYPSESQKLALAESTGLDQKQINNWFINQRKRHWKPSEDMQFVVMDPSHPHYYMDNVLGNPFPMDLSHPML
What is the function of this protein?
Possible transcription activator involved in early embryonic development.  Probably binds to the DNA sequence 5'-TGAC-3'.
What are the official names of this protein?
Homeobox protein SBH1.
What is the protein family that this protein belongs to?
Belongs to the TALE/KNOX homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HEM1_RHOE4
Sequence: MSVLLVGVSHRTAPVPVLERVAVTDTDRPKLIDKLLASSHISEAMIVSTCNRVEVYAVVDAFHGALTEVGEILADHSGLDLTALHAHAYVRYSEAAVEHLFAVASGLDSMVIGEQQILGQIRSAYASSDAQQAAGRVVHELAQQALRVGKRVHSETGIDSAGASVVSVALDRAAGIIGEGGLVGRTAVVVGAGSMGGLSVAHLTRAGIARIVVVNRTQERAEHLAETARSNGVDADGVAFDQLSAAMAQADVMVTCTGAVGAVVTLADVHRALAEPDRDNTKHLVICDLGLPRDIDPAVAGLPGVTVLDMETLQRDPAAGAAASDADAARTIVAGELATYLAGQRLAEVTPTVTALRQRAADVVEAELMRLDSRLPGLDDPQRDEVARTVRRVVDKLLHAPTVRVKQLASAPGGDSYAAALRELFELSPGSPAAVATPTDLVDGDRTGRDLQA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: BIOF_BACHK
Sequence: MNQPWRTHLQTKLKQLHEQGQYRNLHVTEQAEETWLIRDEKRMLNLASNNYLGLAGDERLKEAAIVCTRKYGTGATASRLVVGNYSLYEEVERSICNWKGTEKALVVNSGFTANVGAISSLVCRHDIVFSDKLNHASIVDGIILSGAEHKRYRHNDLNHLEALLKTASPEKRKLIVTDTVFSMDGDTAHLRELVQLKEKYGAIIIVDEAHASGIYGIGGAGLSHIEKDLAQKIDIHMGTFSKALGCYGAYLTGDAIYIEYLQNMMRSFIFTTALPPSTLGAVQKAIEIVQEDHKRRENLIANGEYFRSKLREAGFNIGNSSTHIVPIVVGSNENTLRFSKRLQEAGIAAIAIRPPTVPVHSSRIRFAVTSQHTIADLKWAIDRITHIAKEEELFV
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
Putative 8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: CAV1_RABIT
Sequence: MSGGKYVDSEGHLYTVPIREQGNIYKPNNKAMADEVNEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSTIFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTFCDPLFEAIGKIFSNVRISMQKEI
What is the function of this protein?
May act as a scaffolding protein within caveolar membranes.  Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation.  Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity).  Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity).  Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation.  Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner (By similarity).  Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway (By similarity).  Negatively regulates TGFB1-mediated activation of SMAD2/3 by mediating the internalization of TGFBR1 from membrane rafts leading to its subsequent degradation (By similarity).
What are the official names of this protein?
Caveolin-1.
What is the protein family that this protein belongs to?
Belongs to the caveolin family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Membrane raft. Note=Colocalized with DPP4 in membrane rafts. Potential hairpin-like structure in the membrane. Membrane protein of caveolae (By similarity).
Protein: TM232_HUMAN
Sequence: MNMPVNKSPMINTCGGISSPYHEELWKLNFQHLSGERGHKSRPTFSITKEFILRFNQTQNSKEKEELLELARKIILRCKRKLGLKTLGSGRHVHLPAAWTEVIYLAQCKGEIQDESLNMLYASLDHASFDYDHLPALFFVAESVLYRLCCDASLKTYLYSVEIKLAKIGYLVFLRLFIFFLHGHLESFKQHLLRLQPYLYALSFSGASYHKYPNIFSNVQFILKASEIIGKRELRSESIFRPVEDKKRYENTDSDMGGYEINHLLWHCVAAWSCVQNNSPQLNNVLEHLVFHKTQLQKKCWLDSVLALLVLGEAAKLNMACLKALMDVVRDFVSSIMSVQNQEESCKVDDFSWAWNVVYIYTVILAEICLYAATSDLRKTALIGFCHCKSSQKNILYLDKSVPPELKETSILSLLEYFSSKMSENCDQVVWTGYYGLVYNLVKISWELQGDEEQDGLRNMIWQTLQKTKDYEEDVRIQNAINIAQAELNDPTDPFTRYSTNISSNVGEEVFSKYIGWRIANTLSKLFFPPIEAHFLPLKKPSIKKDQTKYPNKKLESVKKQVLHFTVREHPSVSEIPMFPYPDFFTKADKELAKIIDHHWQEELKIREKEDAICKAQELKDKKLAEKNHFQEVMKKREEKLHKQTKPYELPYRKEVI
What are the official names of this protein?
Transmembrane protein 232.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: M2_I36A0
Sequence: MSLLTEVETPIRNEWGCRCNGSSDPLVIAANIIGILHLILWILDRLFFKCIYRLFEYGLKRGPSTEGVPESMREEYRKEQQSAVDADDGHFVSIELE
What is the function of this protein?
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry.  After attaching to the cell surface, the virion enters the cell by endocytosis.  Acidification of the endosome triggers M2 ion channel activity.  The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur.  Also plays a role in viral proteins secretory pathway.  Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation.
What are the official names of this protein?
Matrix protein 2, Proton channel protein M2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses matrix protein M2 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type III membrane protein. Note=Abundantly expressed at the apical plasma membrane in infected polarized epithelial cells, in close proximity to budding and assembled virions. Minor component of virions (only 16-20 molecules/virion).
Protein: CLU_ASPTN
Sequence: MAQTNGELEHSKGMSSPAVRISQAQKSTKLTVDPESPEQVANGTHAEGEQPEENAGGLFQISVKLPHEPYKIQVMVSSQEQVQDVRQSIVELPSTFQYTCFHLEFNGKRINDFVELSEVPDLKADSEIVLVEDPYTEKEARMHVVRMRELVGAAGDRVDNIQGVNAGLSLHDAIAAEAAAGEASEKEHSLSKYEIAGSSSLKTILPRPETPLPKTVKSIALSPWNPAPYHLRQKGHLLYLQVTTNEGEQFQITSHVSGFYVNKCSNAKFDPFPKTIPKKRSAHSLLTLISQLSPSFNSSFEALQEANNQKDLLTTFPFQNAIPNNPWLVPAPSSNVNAHQPDITRSQENYLISGVDNAETLRDWNEEFQTTRELPRETVQDRVFRERLTSKLFADYNEAAARGAVLVARGEVAPLNPTEERDAQIFVYNNIFYSFGADGVGTFASEGGDEAARVAVGKDVLGIKAVNQLDINGLFTPGTIVVDYLGKRIVGQSIVPGIFKQREPGENQIDYGGVEGKDVVATHPDFVPVFEKLSKALRIKKHPVWDKEGKRHDLEGSVETKGLLGTDGRKYVLDLYRVTPLDVMWQEEEGSDVYPHRMSILRLELVESYWRHKMSQYVKAEVERRRVAKEAAKKEQSETAEPKEEGAEEKSEEALDQERVDISGFSLALNPDVCSGQVPQTAEEKEQWAQDEKEVRDTCDFLRSKVMPELVQDLHDGDVGFPMDGQSLSQLLHKRGINIRYLGKLAQMSKEKGARLDALTTLLVQEMIARAFKHIANNYLRNVPAPFVASCLAHLLNCLLGADVNANPRAEIDSSLREVYPEGDFSFEKATPASLRADIEKQVTIRYRFSLDAEWYNSLRHLQLLRDIAIKLGIQLGARDFVFAKADLPKTPVSNGVNGAGHDDSNSNKKKKKKGGDSNSPARAAVEDKPALSIVVDDIVNVVPLVKDASPRSSLAEEALEAGRISLMQNQKQLGQELILESLSLHEQIYGILHPEVAKLYHQLSMLYYQTDEKEAAVELARKAVIVTERTLGVDSADTILSYLNLSLFEHASGNTKTALVYIKHAMDLWKIIYGPNHPDSITTMNNAAVMLQHLKQYSDSRKWFEASLVVCESLFGRQSINTATILFQLAQALALDQDSKGAVGKMRDAYNIFLQQLGPNDRNTKEAETWLEQLTQNAVSIAKHAKDIQARRLRRINMTPRTLGTRVQPQVGQTAPESAGAKDASNTSLDSRSIDELLKFIEGGDTTSASRSKQKKRAAASNPKLRGSKKSSA
What is the function of this protein?
mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria.
What are the official names of this protein?
Clustered mitochondria protein homolog, Protein TIF31 homolog.
What is the protein family that this protein belongs to?
Belongs to the CLU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGB2_LVX
Sequence: MPLTPPPDYTKPFIAVVVGGTLAAFVLLLTRNTLPHTGDNLHSLPHGGTYCDGTKRIRYGGPHRSHVPELPAKSWALITVVAILIALHFSCLRTHRVHRCVLCHTTSG
What is the function of this protein?
Plays a role in viral cell-to-cell propagation, by facilitating genome transport to neighboring plant cells through plasmosdesmata,.
What are the official names of this protein?
Movement protein TGB2, 12 kDa protein, Triple gene block 2 protein, TGBp2.
What is the protein family that this protein belongs to?
Belongs to the Tymovirales TGBp2 protein family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane.
Protein: PA22_OPICY
Sequence: FMKVIDPGTKWCGPGNKAADDTDNGKN
What is the function of this protein?
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Phospholipase A2 2, OcyPLA2_2.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: IFT81_CHLRE
Sequence: MGDVSYIVDSLGLPPFSYQMSLLSFTEKGPQELLQLLSDVFSTISPKHQKVDVAKEVPDQTADRLIGFLKIIKYRPNVQDPLLFRQLVAAGDRETLYQILRWVVPQAQLLEKRAFVGYYLSFPDMPEEFNFDPDIMELKEEIKAMQQEFIELHKSSDAIKTLSKDTQALKNKIKSLEEEKERLGEKVERAKGAVDKLPDRSSYMEVCTNLRKQQDEEVNLSTAIQTQRALQEKAEASYHRAAARLRELQTSYQEGSAGKLLETLNEDVKNLRAQVNERYPKEVEKRQKRQAALSEALASGISTEMDLQRLQHQATALHNQITEIQERKVAQDKARQGDKAYLQLRQAQQMATVSARKKEELGAKQERLQEKKTALTAQLDKLNAEGGGSGAVFSEEEWRTKYESMKSKLPIYKKMKKELGDLEAEVFVLAHTEELLASQEGGLLEKVKRLEKQQGISGFTETAQHLEKVSEAKSQMDEEKGMTLIEISRTVEEINNAINQRKQQLAPQIKKLRSVRQDFAEFEAKYLEKKTAYDNVVATFEARTSALEGEVSGLKAEVSENETKYHMLHCQLHITDQNIKKVTSGPAAERLRDKYEAKVKEAEDSTKALRDRQREIKDTHSTGLSQIDIMNDMLRLLQLKLNLARGIAVDMSQYGGGGGAAGGANGGMAGQTYDTGSANVLQL
What is the function of this protein?
Component of the intraflagellar transport (IFT) complex B: together with IFT74, forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium.  Binds tubulin via its CH (calponin-homology)-like region.  Required for ciliogenesis.
What are the official names of this protein?
Intraflagellar transport protein 81.
What is the protein family that this protein belongs to?
Belongs to the IFT81 family.
What are the subcellular locations of this protein?
Cell projection, cilium.
Protein: ETT1_CANAW
Sequence: MAKRTLGLAKAAKAKKQKKEQEHQEISASPDEESSSSNQLTIELPEEIDANNEISQLKGLHKTYLQSERDNELLVNGIIHECDRLLRENDSENKQPLPAVFHAIYAIALAELSKFHTEELDKVKEFFIAALERVELGLEKNPNDINLLVAKTKILLDQISLQYIAPLTLESDVKELDKEIDELLDAALSVYESVEARAKELKDYSIFDDSETLDILEALDDILDIVDNFGKENQGDDGSDEDDDEDDDEEEKSVELAETHPLYKIKNSDKYDQWWRDHTHLYLDNLEKLENGSPELKREVCHRLGQSYLQESEVPYSVFTTLKYDDEYDGIEELEGLTEKEAQKISQELITKALDYLKQAKDEEDPETWVSIAEAMISLGNLYEVDSKEQEDLYLEAEKILKRANNVTNGKFQEELDNLLP
What is the function of this protein?
Required for correct translation termination and probably involved in regulation of hypoxic gene expression.
What are the official names of this protein?
Enhancer of translation termination 1.
What is the protein family that this protein belongs to?
Belongs to the ETT1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LEUD_SHEON
Sequence: MQPFTCHTGLAVMIDSANIDTDQIIPKQFLSKVTRDGFGVHLFHDWRYLDDAGDVPNPEFTLNKPRYNGASILLAQENFGCGSSREHAPWALADFGLRAIIAPSFADIFYGNSINNGLLPVKLSANEVRQLMDEVASEEGAQITVDLTTCQVTSPSGAQFSFSLAESARHKLLNGLDAIGLTLSHGAQISEYESQIPSWRR
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.