PharMolix/UniProtQA huggingface dataset:
Protein: ATP5I_RAT
Sequence: MVPPVQVSPLIKFGRYSALILGMAYGAKRYSYLKPRAEEERRIAAEEKKRLDELKRIERELAEAEDVSIFK
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane.
What are the official names of this protein?
ATP synthase subunit e, mitochondrial, ATPase subunit e, ATP synthase membrane subunit e.
What is the protein family that this protein belongs to?
Belongs to the ATPase e subunit family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane.
Protein: SERC_BORBR
Sequence: MMARPWNFSAGPSALPEAVLQQAAAEMLDWHGSGMSVMEMSHRGKHFVQICDEAEADLRELLGLPADYAVMFMQGGGLGENAIVPMNLMGRRSTPAADFVVTGHWSTRSHKEAGRYGDAQIAASAAEATEIDGQAQSSWTWLPPVDTWRVRKDSAYLHLCSNETIGGVEFTEWPDPASLGAPDVPLVVDVSSHFLSRPLDIARAGLVFAGAQKNAGPAGVTVVIARRDLLGHALPICPSAFDYANVAADHSRYNTPPTFAIYVMGLVFKWIKAHGGVRGMEEANRAKAELLYGYLDGSAFYRNPVQPAVRSRMNVPFVLRDESLNDAFLQGAEAAGLMQLKGHKSVGGMRASIYNAMPLAGVQALIDYLKEFERRHG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPGD_SHIFL
Sequence: MDRRRFIKGSMAMAAVCGTSGIASLFSQAAFAADSDIADGQTQRFDFSILQSMAHDLAQTAWRGAPRPLPDTLATMTPQAYNSIQYDAEKSLWHNVENRQLDAQFFHMGMGFRRRVRMFSVDPATHLAREIHFRPELFKYNDAGVDTKQLEGQSDLGFAGFRVFKAPELARRDVVSFLGASYFRAVDDTYQYGLSARGLAIDTYTDSKEEFPDFTAFWFDTVKPGATTFTVYALLDSASITGAYKFTIHCEKSQVIMDVENHLYARKDIKQLGISPMTSMFSCGTNERRMCDTIHPQIHDSDRLSMWRGNGEWICRPLNNPQKLQFNAYTDNNPKGFGLLQLDRDFSHYQDIMGWYNKRPSLWVEPRNKWGKGTIGLMEIPTTGETLDNIVCFWQPEKAVKAGDEFAFQYRLYWSAQPPVHCPLARVMATRTGMGGFPEGWAPGEHYPEKWARRFAVDFVGGDLKAAAPKGIEPVITLSSGEAKQIEILYIEPIDGYRIQFDWYPTSDSTDPVDMRMYLRCQGDAISETWLYQYFPPAPDKRQYVDDRVMS
What is the function of this protein?
Probably involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis protein D.
What is the protein family that this protein belongs to?
Belongs to the OpgD/OpgG family.
What are the subcellular locations of this protein?
Periplasm.
Protein: ZUO1_YEAST
Sequence: MFSLPTLTSDITVEVNSSATKTPFVRRPVEPVGKFFLQHAQRTLRNHTWSEFERIEAEKNVKTVDESNVDPDELLFDTELADEDLLTHDARDWKTADLYAAMGLSKLRFRATESQIIKAHRKQVVKYHPDKQSAAGGSLDQDGFFKIIQKAFETLTDSNKRAQYDSCDFVADVPPPKKGTDYDFYEAWGPVFEAEARFSKKTPIPSLGNKDSSKKEVEQFYAFWHRFDSWRTFEFLDEDVPDDSSNRDHKRYIERKNKAARDKKKTADNARLVKLVERAVSEDPRIKMFKEEEKKEKERRKWEREAGARAEAEAKAKAEAEAKAKAESEAKANASAKADKKKAKEAAKAAKKKNKRAIRNSAKEADYFGDADKATTIDEQVGLIVDSLNDEELVSTADKIKANAAGAKEVLKESAKTIVDSGKLPSSLLSYFV
What is the function of this protein?
Component of the ribosome-associated complex (RAC), a heterodimeric chaperone complex involved in regulation of accurate translation termination and in folding or maintaining nascent polypeptides in a folding-competent state.  RAC stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones SSB1/SSB2 that bind to the nascent polypeptide chain.  ZUO1 can act as a J-protein for SSB1/SSB2 only when associated with SSZ1.
What are the official names of this protein?
Zuotin, DnaJ-related protein ZUO1, J protein ZUO1, Heat shock protein 40 homolog ZUO1, Ribosome-associated complex subunit ZUO1.
Protein: 53DR_STAES
Sequence: MTRQRIAIDMDEVLADTLGAVVKAVNERADLNIKMESLNGKKLKHMIPEHEGLVMDILKEPGFFRNLDVMPHAQEVVKQLNEHYDIYIATAAMDVPTSFHDKYEWLLEYFPFLDPQHFVFCGRKNIILADYLIDDNPKQLEIFEGKSIMFTASHNVYEHRFERVSGWRDVKNYFNSIEK
What is the function of this protein?
Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides.
What are the official names of this protein?
Putative 5'(3')-deoxyribonucleotidase.
What is the protein family that this protein belongs to?
Belongs to the 5'(3')-deoxyribonucleotidase family.
Protein: KLK10_HUMAN
Sequence: MRAPHLHLSAASGARALAKLLPLLMAQLWAAEAALLPQNDTRLDPEAYGSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQGEQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDRGQDPCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN
What is the function of this protein?
Has a tumor-suppressor role for NES1 in breast and prostate cancer.
What are the official names of this protein?
Kallikrein-10, Normal epithelial cell-specific 1, Protease serine-like 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Kallikrein subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ATG8I_ARATH
Sequence: MKSFKEQYTLDERLAESREIIAKYPTRIPVIAEKYCKTDLPAIEKKKFLVPRDMSVGQFIYILSARLHLSPGKALFVFVNNTLPQTAALMDSVYESYKDDDGFVYMCYSSEKTFG
What is the function of this protein?
Ubiquitin-like modifier involved in autophagosomes formation.  May mediate the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton.
What are the official names of this protein?
Autophagy-related protein 8i, Autophagy-related ubiquitin-like modifier ATG8i, AtAPG8i, Protein autophagy 8i.
What is the protein family that this protein belongs to?
Belongs to the ATG8 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Vacuole membrane; Lipid-anchor. Cytoplasm, cytoskeleton.
Protein: ARHGF_MOUSE
Sequence: MSAQSLPAATPPTLKPPRIIRPRPPSRHRAPHSPGPLHNGSSPKALPQISNDASASVCTSIFWEPPTASLKPPALLPPSVSRTSLDSQTSPDSPSSTPSPSPVSRRSISPEPAPCSPVPPPKPSGSSRTPLPSGPTPLQDGSASAPGTVRRLAGKFEWGAEGKAQSSDSLERCSQGSTEVNGEKETPEAALSGNGSQENGTPDAALACPPCCPCVCHVAKPGLELRWVPVGSSEDILRIPCRASPLRASRSRINPPVISHPPVVLTSYRSTAERKLLPPLKPPKPTKVRQDISTSEELPQPDLKLPSEDGIQTATKAWEGDRPEGAPLNAPPVALEGREEEGLDGLKGLQWELPLQDEPLYQTYRAAVLSEELWGVGEDGGPSPANPGEAPTFSRLPGPRNTLWQELPAVRGSGLLESLSPQERRMQESLFEVVTSEASYLRSLRLLTDTFVLSQALRDTLTPRDHHTLFSNVQRVQSVSERFLGTLLSRVRSSPHITDLCDVVHAHAVGPFFVYVDYVRNQQYQEETYSRLMDTNVRFSAELRRLQSLPKCERLPLPSFLLLPFQRITRLRMLLQNILSQTEEGSSRQENAQKALGAVSKIIERCSAEVGRMKQTEELIRLTQRLRFHKVKALPLVSWSRRLELQGELTELGCRRGGVLFTSRPRFTPLCLLLFSDLLLITQPKSGQRLQVLDYAHRSLVQAQQVPDPSGPPTFRLSLLSNHQGRPTHRLLQAASLSDMQRWLGAFPTPGPLPCSPDTIYEDCECSQELCSEPSTPSKTEGQSLESKAPRKHLHKNPEGWLKGLPGAFPAQLVCEVTGEHERRKHLRQHQKLLEAVGPSSGTPDTPQP
What is the function of this protein?
Specific GEF for RhoA activation.  Does not activate RAC1 or CDC42.  Regulates vascular smooth muscle contractility.  Negatively regulates excitatory synapse development by suppressing the synapse-promoting activity of EPHB2.
What are the official names of this protein?
Rho guanine nucleotide exchange factor 15, Ephexin-5, E5.
What are the subcellular locations of this protein?
Cell projection, dendrite. Note=Expressed exclusively in dendrites of the developing hippocampus.
Protein: ENGB_STRPM
Sequence: MAEEQVLNTHNASILLSAANKSHYPKDDLPEIALAGRSNVGKSSFINTILGRKNLARTSSKPGKTQLLNFFNIDDKLRFVDVPGYGYAKVSKSERAKWGKMIEEYLTSRDNLRAVVSLVDLRHAPSKEDIQMYDFLKYYDIPVIVVATKADKIPRGKWNKHESVVKKALNFDNSDTFIVFSSVERIGIDDSWDAILEQV
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: RN2A_RANCS
Sequence: GILSSFKGVAKGVAKDLAGKLLETLKCKITGC
What is the function of this protein?
Antibacterial peptide with amphipathic alpha-helical structure.  Active against E. coli ATCC 25726 (MIC=4-5 uM) and S. aureus ATCC 25923 (MIC=8-10 uM).  Has a weak hemolytic activity on human erythrocytes (LC(50)=150-160 uM).
What are the official names of this protein?
Ranatuerin-2CSa.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Ranatuerin subfamily.
Protein: RL33_HAEDU
Sequence: MAAKGNREKIKLVSTAETGHFYTTTKNKRNMPEKMEIKKFDPVVRKHVIYKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: SYP_BURO1
Sequence: MKASRFFIGTLKEAPADAEIVSHKLMVRAGMIRRVAGGIYNYLPVGLRSIRKVEAIVREEMNRAGAIELLMPAVQPAELWQESGRWEQYGPELLRFKDRKDNDFVIGPTHEEVVTDIARNQIKSYRQMPVNFYQIQTKFRDEIRPRFGVMRGREFIMKDAYSFDKDAAGLNESYRKMYDAYVRIFTRLGLEFRAVAADSGSIGGNFSHEFHVIADTGEDAIAYCPTSEFAANVEAAEALPLIAERAAPAEAMEKVATPGKAKCEAVAELLSIPLERTIKSIVLATDNEGAEPTIWLVMLRGDHDLNEIKASKLPGLKNHRFATEQEIVEWFGTPPGYLGPVGTKKPVKVIADRTVANMSDFVVGANEVDYHIAGVNWGRDLPEPEVADVRNVKKGDPSPDGKGVIDICRGIEVGHVFQLGTKYSEAMGATFLDESGKPQPMLMGCYGVGITRILGAAIEQNFDDKGIIWPESIAPFEVVLCPMGYDRSDMVRETADKLYAELVAAGIDVILDDRGERPGVMFADWELIGVPHRLVIGERGLKEGKIEYQGRRDAEATLLPADTAAAAVAEKIRAALAH
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
Protein: SSRP_PHOV8
Sequence: MKPTPINIKNKRASFDYEFIDTYTAGIVLTGTEIKSIRLGKASLVDTYCYFVQGELWVKNMHIAEYFYGSYNNHSARRERKLLLNKKELRKLEEAGKNPGFTIVPVRLFINEKGLAKLVVALAKGKKQYDKRESLKEKDDRREMDRMFKR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: Y750_ALCBS
Sequence: MAGHSKWANIKHRKAAQDAKRGKIFTKLIRELTVAAKMGGGEPNDNPRLRAAIDKALGQNMTRDTIDRAVKRGAGGDDDGSMDEITYEGYGKGGVAVLVETMTDNVNRTVAEVRHAFSKFGGNLGTSGSVAFLFTKRGEIFFEPGVDEEKLMEVALEAGAEDVEEMGDDGFLVITTPDKSFGEVVDSLRAAGLEFAEAEVTMHPSTEAEMDTDTAETVQKMIDMLEDLDDVQNVYTNASWPAPQEEE
What are the official names of this protein?
Probable transcriptional regulatory protein ABO_0750.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MANB_PIRSP
Sequence: MNSLSLLLFCIFFVFSTFAKKVYYEAENGKLDGVTVYKSDLTGFSGTGYVGRFENPGNSVTVTVEVPQTGMYDLTIVYCANMGQKINSLTVNGQSAGDITFTENTKFEDLNVGAIYLNKGKNTIGLVSSWGWMWVDAFVINDAPNAAKDVTSKLNPTLINPKAIPAAKKLYDFLKTNYGKRILSGQVGAAGQAGDEGQEIQRIQKATGKLPAVWNMDFIFESNDCTWRPQNPDITEMAINWWKKYQGKGIMSAQWHWNIAGKTGDFAFYKKDTTFSIDNAVTEGTWEYEKIIKDIDRVAGHIKKLQAVNMPLIWRPLHENDGDWFWWGNNPKSCAKLWKILYERMVNYHGLNNLIWLWNGKNDANTPVDYIDIIGVDIYANDHGPQTTAYNTHFDFYGGKKMVVLSENGRIPDIQQCVDQNAWWGYFQTWNSEFILQDSYHTDAQLKEYFTHKTVMNMDELPSFNVNSYEYQSGNNNNNSSNNNNNNNSSECFSIPLGYPCCKGNTVVYTDNDGDWGVENNEWCGIGNSSSAVVCWSEALGYPCCVSSSDVYYTDNDGEWGVENGDWCGII
What are the official names of this protein?
Mannan endo-1,4-beta-mannosidase B, 1,4-beta-D-mannan mannanohydrolase B, Beta-mannanase B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 26 family.
Protein: RS14Z_NOCFA
Sequence: MAKKALVNKANRKPKFAVRAYTRCQRCGRPHAVYRKFGLCRVCLRDMAHKGELPGVHKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: RLMH_RHOPS
Sequence: MRLTVIAIGKLKQGPERELAERYRGRFDDLGRKLGFRGLDIHEIAESRARDAAGRMAEEAAAIAALIAEGSSLVTLDERGKSVDSAAFAAQLGRWRDESVPGTIFVIGGADGLLPELRRKAKLCLSFGAATWPHQMVRVMLLEQIYRAATILAGHPYHRA
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_RHOPB
Sequence: MIGKLKGLIDSYGEDYVILDVQGVGYQVHCSARTLQALPQAGGAAVLSIETYVREDQIKLFGFRSDLEREWFRLLQTVQGVGAKVALAVLSTLPPADLANAIALRDKAAVARTSGVGPKVAERIVTELKDKAPAFASVDPAVVALSGALDERSAPRPVTDAISALVNLGYGQPQAAAAIASASRSAGEGAETAQLIKLGLKELSK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: PURQ_PROMT
Sequence: MNIGIIVFPGSNCDRDVRWATEGCLGVPTSFLWHETTDLDGFDAIVIPGGFSYGDYLRCGAIARFAPVLNSLISFVDKGGKVLGICNGFQILTELGLLQGALTRNKNLHFICDRANLSIESTKSTWMKNYKKHDSISLPIAHGEGRYQCSSDVLKKLQDDDSVALRYADNPNGSIHDIAGITNKKGNVLGMMPHPERACDDALGDIDGKSILSTLLS
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFH5_NEOFI
Sequence: MADQQPEKTTAPATDVADSQPAVVTSTDTRKETTETAEPLPEDKTETTTAQPAVETTATQSGTAETPAEVQQPPQAEEEKPVAQQPEQPAYLAKNPALAQFFERLPAIVSSSGHAEMWGVPLKDSNDAPTVNVLIKFLRANEGNVKLAEGQLTKALKWRKEMNPSALAESTSYSATKFGGLGYLTVYKEANGAENVVTWNIYGGVKDINTTFGDMDEFVKWRVALMELAVKELKMAEATSVIDYDGEDPYQMIQVHDYQNVSFLRLNPAIKAATKKTIEVFTTAYPELLREKFFVNVPAIMGWMFAAMKVFLSKNTTRKFHPISNGANLAREFPSLKDQFPKVYGGSAPALQEGARTVNLSQDESAPAAPEQSKEQTKENKEEAAQEESKPESAPEQPKADPAVTAQEAPAADAK
What is the function of this protein?
Non-classical phosphatidylinositol (PtdIns) transfer protein (PITP), which exhibits PtdIns-binding/transfer activity in the absence of detectable PtdCho-binding/transfer activity.  Regulates PtdIns(4,5)P2 homeostasis at the plasma membrane.  Heme-binding protein that may play a role in organic oxidant-induced stress responses.
What are the official names of this protein?
Phosphatidylinositol transfer protein sfh5, PITP sfh5.
What is the protein family that this protein belongs to?
Belongs to the SFH5 family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: SURE_CLOBL
Sequence: MNILLTNDDGIEAEGINTLAELLSKYHNVTMVAPENQRSASSHSITIYEPIIVKQVKKPYNIEAYSISGTPADCVRVALDKLVPDNIDMVISGINKGLNIGNDILYSGTVSAAIEGAMYKVPSMAVSAQFIKNKKENYKIAAKYALGMLNRLKKEDLKNDVVLNLNIPFCSEEEIKGIKVCKVGNKIFNTRFSEEIDEEGNKVLKLEGDINKDIYEGTDVYYIRNKYVTLTPLHYDLTNFNILEETEQLFLS
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU_DESVV
Sequence: MGKEKFERKKPHVNIGTIGHIDHGKTTLTAAITKTAGLLGQGKFIAYDEIDKAPEEKERGITIATAHVEYETATRHYAHVDCPGHADYIKNMITGAAQMDGAIIVVAATDGPMPQTREHILLARQVGVPYIVVFLNKCDMVDDEELLELVELEVRELLTSYGFPGDDVPVVRGSALKALESDDPNSDACKPIRELLAACDSYIPEPQRDIDKPFLMPIEDVFSISGRGTVVTGRVERGVIKVGEEVEIVGIKDTTKSTCTGVEMFRKLLDQGQAGDNIGALLRGVKRDDVERGQVLAAPKSITPHRKFKAEVYVLSKEEGGRHTPFFSGYRPQFYFRTTDITGVITLEEGVEMVMPGDNATFNVELIAPIAMELGLRFAIREGGRTVGAGVVSEIVE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_SHIBS
Sequence: MNIIEANVATPDARVAITIARFNNFINDSLLEGAIDALKRIGQVKDENITVVWVPGAYELPLAAGALAKTGKYDAVIALGTVIRGGTAHFEYVAGGASNGLAHVAQDSEIPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVLKAIKA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: WDR5B_HUMAN
Sequence: MATKESRDAKAQLALSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISAACHPTENLIASAALENDKTIKLWMSNH
What is the function of this protein?
May function as a substrate receptor for CUL4-DDB1 ubiquitin E3 ligase complex.
What are the official names of this protein?
WD repeat-containing protein 5B.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR5/wds family.
Protein: ATG3_PICST
Sequence: MLRSKLSSLREYLTPINHNSNFSTTGEISPEEFVQAGDYLVYKFPTWQWSTCPKNLQKSFLPADKQFLITRHVPSYQRASNYLTGGNVDFDDDEEYEDDEEGDGWVKSRKVVSVTKPQDGQEEEPQEINDIDDLIDVTAEGAEDDGDNLEDFDDLDIRNDGGSVRKYDMYITYSTSYRVPKMYLVGFNANGIPLTPDQMFEDINADYKDKTATIENLPVAHNTTSVSIHPCKHSSVMKVLMKHSKSKKTREEVNHLSEELGKTNISDKSQEDTGKDAEAAAGPEAEDSIRVDQYLVIFLKFIASVTPGIEYDYTMDAL
What is the function of this protein?
E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8.  The ATG12-ATG5 conjugate plays a role of an E3 and promotes the transfer of ATG8 from ATG3 to phosphatidylethanolamine (PE).  This step is required for the membrane association of ATG8.  The formation of the ATG8-phosphatidylethanolamine conjugate is essential for autophagy and for the cytoplasm to vacuole transport (Cvt).  The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy (By similarity).
What are the official names of this protein?
Autophagy-related protein 3, Autophagy-related E2-like conjugation enzyme ATG3.
What is the protein family that this protein belongs to?
Belongs to the ATG3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y36_VACCW
Sequence: MQHANCNREIKIYEGAKHHLHKETDEVKKSVMKEIETWIFNRVK
What are the official names of this protein?
Uncharacterized protein 36.
Protein: DEF_IDILO
Sequence: MAKMTVLQYPDERLRKVAQKIEKVDDNIRSVIDDMFETMYEEQGVGLAATQVDVHRRLFVSDCSEDQNEPLVFINPEITEAEGHFKNDEGCLSFPGVYAKVERAERITVTALDKNGERFSRSAEGLLAICIQHEIDHLDGKLFVDYLSPLKRERIRKKLEKEQRLAEKQAAEAQ
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: PSTB_BARQU
Sequence: MKIKMRGQDVKVFYKDKEALHGITLDIPEHKVTALIGPSGCGKSTFLRCFNRMNDTIEGAKITGLITLDGENIYDSQIDVVELRARVGMVFQKPCPFPKSIFENVAYGPRIHGLVKSRAELHDIVEKSLRQAGLFEEVKDRLHEAGTSLSGGQQQRLCIARAIAVSPEVILMDEPCSALDPIATARIEELIDALRKDYTIVIVTHSMQQAARVSQYTAMFHLGHLVEVGATEMIFTSPKEQRTQDYITGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.