PharMolix/UniProtQA huggingface dataset:
Protein: DPAL_ECOLI
Sequence: MSVFSLKIDIADNKFFNGETSPLFSQSQAKLARQFHQKIAGYRPTPLCALDDLANLFGVKKILVKDESKRFGLNAFKMLGGAYAIAQLLCEKYHLDIETLSFEHLKNAIGEKMTFATTTDGNHGRGVAWAAQQLGQNAVIYMPKGSAQERVDAILNLGAECIVTDMNYDDTVRLTMQHAQQHGWEVVQDTAWEGYTKIPTWIMQGYATLADEAVEQMREMGVTPTHVLLQAGVGAMAGGVLGYLVDVYSPQNLHSIIVEPDKADCIYRSGVKGDIVNVGGDMATIMAGLACGEPNPLGWEILRNCATQFISCQDSVAALGMRVLGNPYGNDPRIISGESGAVGLGVLAAVHYHPQRQSLMEKLALNKDAVVLVISTEGDTDVKHYREVVWEGKHAVAP
What is the function of this protein?
Catalyzes the alpha,beta-elimination reaction of both L- and D-alpha,beta-diaminopropionate (DAP) to form pyruvate and ammonia.  In vitro the D-isomer of serine is degraded to pyruvate, though very poorly; other amino acids (L-serine, D- and L-threonine, D- and L-beta-Cl-alanine) are not substrates.  In vivo allows poor growth on L-DAP or a DL-DAP mixture but not on D-DAP alone, this may be due to a poor promoter.  DL-DAP is toxic in the absence of this enzyme, it may inhibit enzymes involved in the synthesis of pyruvate and aspartate, as well as amino acids derived from them.
What are the official names of this protein?
Diaminopropionate ammonia-lyase, DAPAL, 2,3-diaminopropionate ammonia-lyase, Alpha,beta-diaminopropionate ammonia-lyase, Diaminopropionatase.
What is the protein family that this protein belongs to?
Belongs to the diaminopropionate ammonia-lyase family.
Protein: WECB_SALTI
Sequence: MKVLTVFGTRPEAIKMAPLVHALEKDPHFEAKVCVTAQHREMLDQVLTLFSIVPDYDLNIMQPGQGLTEITCRILERLKPILADFKPDVVLVHGDTTTTIATSLAAFYQRIPVGHVEAGLRTGDLYSPWPEEANRTLTGHLAMYHFAPTENSRQNLLRENIPDERIFVTGNTVIDALIWVRDRVLTSDTLQAELAEQYPFLNANKKMILVTGHRRESFGQGFEHICQALAEIAAANQNVQIVYPVHLNPNVSEPVNRILGHVENVVLIEPQDYLPFVWLMNHAWLILTDSGGIQEEAPSLGKPVLVMRETTERPEAITAGTVRLIGTDSRRIVAEVMRLLHDENEYQTMSRAHNPYGDGQSCARILQALKSYRVSL
What is the function of this protein?
Catalyzes the reversible epimerization at C-2 of UDP-N-acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues.
What are the official names of this protein?
UDP-N-acetylglucosamine 2-epimerase, UDP-GlcNAc-2-epimerase.
What is the protein family that this protein belongs to?
Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHOX4_ARATH
Sequence: MGKPTAKKKNPETPKDASGGGGGGGGKSGKTYHRSTSRVFDEDMEIFISRALELKEEGNKLFQKRDHEGAMLSFDKALKLLPKDHIDVAYLRTSMASCYMQMGLGEYPNAISECNLALEASPRYSKALVRRSRCYEALNKLDYAFRDARIVLNMEPGNVSANEIFDRVKKVLVDKGIDVDEMEKDFVDVQPVCAARLKKIVKERLRKSKKKKKSGGKDEELKSPKVVVVDKGDEAEGRNKPKEEKSDKSDIDGKIGGKREEKKTSFKSDKGQKKKSGGNKAGEERKVEDKVVVMDKEVIASEIVDGGGSKKEGATVTRTIKLVHGDDIRWAQLPLDSTVRLVRDVIRDRFPALRGFLIKYRDTEGDLVTITTTDELRLAASTHDKLGSLRLYIAEVNPDQEPTYDGMSNTESTDKVSKRLSSLADNGSVGEYVGSDKASGCFENWIFQFAQLFKNHVGFDSDSYVDLHDLGMKLYTEAMEDAVTGEDAQELFQIAADKFQEMGALALLNWGNVHMSKARKQVCIPEDASREAIIEAVEAAFVWTQNEYNKAAEKYEEAIKVKPDFYEALLALGQEQFEHAKLCWYHALKSKVDLESEASQEVLKLYNKAEDSMERGMQIWEEMEECRLNGISKLDKHKNMLRKLELDELFSEASEEETVEQTANMSSQINLLWGSLLYERSIVEYKLGLPTWDECLEVAVEKFELAGASATDIAVMVKNHCSSESALEGMGFKIDEIVQAWNEMYDAKRWQMGVPSFRLEPMFRRRAPKLHDILENVFSGPV
What is the function of this protein?
Carboxylate clamp-type tetratricopeptide repeat protein that may act as a potential Hsp90/Hsp70 co-chaperone (PubMed:20856808).  Contributes to polar growth of root hairs (PubMed:28096376).
What are the official names of this protein?
Protein PHOX4.
Protein: GLMU_SHESH
Sequence: MALNVVILAAGKGTRMRSELPKVLHPIAHKSMVQHVIDTAHSVGSDAIQLVYGYGAEKLQSVLGEQQLNWVLQAEQLGTGHAVAQANDNIGDDDTVLILYGDVPLIQASTLEALLAAREDNGLAILTVNLANPMGYGRIVREANKVVGIVEQKDASAEQLAINEINTGIMAAPGKQLKAWLGQLSSDNAQGEYYLTDIVAMAHKDGVEITTAQPESAIEVEGANNRVQLAQLERAYQARAAEKLMLEGANLRDPARLDIRGDVTVGMDVMIDINVIIQGKVTIGNNVTIGAGAILIDCEIGDNAEIKPYSIVENAKLGVEASAGPFARLRPGAELKRDAHIGNFVEMKKAVLGEGSKAGHLAYIGDAQIGCGVNIGAGTITCNYDGANKHLTVIEDNVFVGSDTQLVAPVTIGKGATLGAGSTITSNVAEGELVITRVKQRHLTGWARPVKKPKS
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BURPF_ORYSJ
Sequence: MASLVAIAIAMALMVVQPGRQMTAFAARTSPAAAAEAFWRAAMPGAPMPDAIVELLHHEHGVASAGGKANGGGDGPPPPMNFNYDDYRALPRSDAPSPDALNRVAAVQNADENGVSSPPPPPPTVFFLEDAVRVGESLPLPRPAADATAAGAAAATALPPLRLYTVRSVRAIEGSSFVVCRGETTAGAGVYGCRDAATGPARAYAVDAAGGGGGDAVIAAVVCHADTSRWDPDHAAFRLLGVRPGGAAVCRAVADAHILPTNKD
What are the official names of this protein?
BURP domain-containing protein 15, OsBURP15, Anther-specific protein 8.
Protein: FLMC1_ECOLI
Sequence: MLRQHQDSLLLRFAQGEEGHETTTQLSCLVCVDRVSHTVDIHLSDTKIAVRDSLQRRIQGGGGFHGLRIR
What is the function of this protein?
Component of a type I toxin-antitoxin (TA) system (Probable).  Either this protein or sequences upstream of it are required for translation of downstream flmA; this could be translationally coupled to flmA (PubMed:3049248).
What are the official names of this protein?
Protein FlmC, F-plasmid maintenance protein C.
Protein: PRMA_BURP1
Sequence: MSYRELVAELPREHAEALSDALVELGALSVSVEDADADTPDEQPLFGEPGLVPERTAWQHSRVIALVDATQDPAVLLAAAANEAGLAQAPRFELREVEEQDWVRLTQSQFEPIHIGEKIWVVPSWHDAPQPDALVLELDPGLAFGTGSHPTTRLCMEWLEQTVQPGQTVLDYGCGSGILAILAKKCGAGRVTGIDIDPQAVEAARHNSERNRADVTYGLPDDCPDGEFDIVVANILSNPLKLMASMLASKVKPGGRIALSGVLARQADEVASVYARYIDIAVWREHEGWVCLAGTRRESH
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEXA_RHIE6
Sequence: MLTRKQQELLLFIHERMKESGVPPSFDEMKDALDLASKSGIHRLITALEERGFIRRLPNRARALEVIKLPEAYSPSLQPRRGFSPSVIEGSLGKPPAVAAPAAAKPIADNGNSVSVPVMGRIAAGVPISAIQNNTHDIVVPADMLGSGEHYALEVKGDSMIDAGIFDGDTVIIRNGSTASPGDIVVALVDDEEATLKRFRRKGASIALEAANPAYETRIFGPDRVKVQGKLVGLIRRYH
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: HIS4_PARP8
Sequence: MLLIPAIDLKDGQCVRLKQGDMDQATIFHEEPAVMARHWVDRGARRLHLVDLNGAFAGKPKNEDAIRAIIEEVGGEIPVQLGGGIRDLNTIERYLDDGLEYVIIGTAAVKNPGFLLEACTAFGGHIIVGLDAKDGKVATDGWSKLTGHEVADLARKFEDYGCESIIYTDIGRDGMLQGINIEATVRLARAVKIPVIASGGLSNLGDIEALCEVEDEGIEGVICGRAIYSGDLDFAAAQTHADRLRESDDA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_SYNSC
Sequence: MARLIDQFERLPGIGPRTAQRLALHLLNQPQEQIHQFADALLAARTQVGQCQTCFHLSADPECEICRNPERRNGVICVVADSRDLLALERTREFHGRYHVLGGLISPMDGIGPELLRVTELVQRISNEEISEVILALTPSVEGDTTSLYLGRLLKPFCSVSRIAYGLPMGSELEYADEVTLSRALEGRRPV
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: KN7H_ARATH
Sequence: MTTEDDDQMLGPSGTQEKIYVSVRMRPLNDKEKFRNDVPDWECINNTTIIYRSHLSISERSMYPSAYTFDRVFSPECCTRQVYEQGAKEVAFSVVSGVNASVFAYGQTSSGKTYTMSGITDCALVDIYGYIDKHKEREFILKFSAMEIYNESVRDLLSTDTSPLRLLDDPEKGTVVEKLTEETLRDWNHFKELLSVCKAQRQIGETALNEVSSRSHQILRLTVESIAREFSTNDKFSTLTATVNFIDLAGSERASQSLSAGTRLKEGCHINRSLLTLGTVIRKLSKEKTGHIPFRDSKLTRILQSSLGGNARTAIICTMSPARIHVEQSRNTLLFASCAKEVTTNAQVNVVMSDKALVKHLQRELAKLESELRSPSQASIVSDTTALLTEKDLEVEKLKKEVFQLAQQLEQARSEIKDLRRMVEEEKNQEKETLSTETEGLNVLMEHQYPKLRVRRTWDSENTTPLSPISAHRSSISPRSTEYSYEENVFQLSDFRIDSASSSPQQLAFVTPFLKVPLDDIHVTDTVDQSHVHKEEAIEEPHVQEERFYEMAEHTDGNSEDNCREVRCIETEKSDISIGPVENMPESSPDKYEAVTAEEPVSVTEPKNLQHPTEEAVCVTETKNLQHPTEAENEEEEEEERVKEVSGASPEPKQESNLTKNPALCDLECSPDEFDTSMSNLSRISTPPALITPSPEKPFSWIMERDSQLFRGMKLTRSRSCRPSLLSSPSSSWLEKDADTPPSWYDKEFIKTAERNLTMCDIKNQRLLQDEFSGRSMPTTWFERSLSDTQTVDAASHGVSNEMSPNESPFRPSDASVFELQTSGRASISQDRTEETAAQKDKQIIHRSMEEREQKFLASNSTKSFKDAAMDPIQDYLDTALNWPVEFKRLQREIIELWHVCKVSMAHRSYFFLLFRGDQKDCLYLEVELRRLKYIRESFAQNSNDGNNMTLISCTRALTRERYKLSKLMQRKLSKEERENLFLRWGIGLNTNHRRVQLARRLWSDYKDMGHVRESASLVGKLNGFVDMKLTSTEMFGVNYAFRPPRPKKSSLWKRSVLSLSFL
What are the official names of this protein?
Kinesin-like protein KIN-7H.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-7 subfamily.
Protein: ZIPA_SHESM
Sequence: MEDLQLVLFVLGAIAIVAVLVHGFWSIRRQQPKSLKDSPMGNFYKKQAERGEGAPKRVDADGFDADGIGAVRVRKANEAHTPEAPAFNPYLKQEAKTQPQPVEPVQVEPKPLFEQEPSMAQPDFSLQSPTAKEQHRGPKASRQEPVLQGHSANLAQAHVGQSHAAMVAQKVAEEQRAQVQMPTQTALFDDEEPYEEEQSQAVEQADDDLGEPRDVLVLHVVAKEGQQLNGAELLPCFLTLNFKYGDMNIFHRHVDNAGNGKVLFSIANMVKPGVFDPDNMEQFSTQGVVFFMTLPCYGDALMNFSIMLNSARQLADDIDAVVLDGQRQPWGEFTKQDYLHRIRANA
What is the function of this protein?
Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring.  Also required for the recruitment to the septal ring of downstream cell division proteins.
What are the official names of this protein?
Cell division protein ZipA.
What is the protein family that this protein belongs to?
Belongs to the ZipA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type I membrane protein. Note=Localizes to the Z ring in an FtsZ-dependent manner.
Protein: Y693_STAEQ
Sequence: MTQYTFSPKDFKAFEVEGLDQRMEALNDYVRPQLHQLGSYFEEYFTTQTGETFYAHVAKHARRSVNPPIDTWVAFAPNKRGYKMLPHFQIGLFRNQLFIMFGIMHEGRNKEEKVKIFDKHFDKLTSLPSDYSVSLDHMKTEKHYIKDMSNEELHAAIDRVKNVKKGEFFVARTLSPTDKRLKSDKSFLKFVEETFDEFLKFYQ
What are the official names of this protein?
UPF0637 protein SERP0693.
What is the protein family that this protein belongs to?
Belongs to the UPF0637 family.
Protein: RBFA_BUCBP
Sequence: MQKLNRSFKISNEIKKKISWIICYQLCDPRLFNILISVSSVNLSRDFSYAKIYVSILNNKNISFKEILTILQNSSKHIRYLLAKGIFLRIIPTLHFCHDSSYVNGTKITNLINNVLYNK
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSPQ_YERPN
Sequence: MIASKFGIGQQVRHSLHGYLGVVIDIDPEYSLAPPEPDEVANNKTLRSSPWYHVVIEDDDGQPVHTYLAEAQLTYEDVDAHPEQPSLDELAASIRHQLQAPHLRN
What is the function of this protein?
Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress.
What are the official names of this protein?
Heat shock protein HspQ.
What is the protein family that this protein belongs to?
Belongs to the HspQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTTB2_MOUSE
Sequence: MATDSASCEPDLSRTPGDTEGATAEAAKKEFDVDTLSKSELRMLLSVMEGELEARDLVIEALRARRKEVFIQERYGRFNLNDPFLALQRDYEAGPGDKEKPVCTNPLSILEAVMAHCRKMQERMSAQLVAAESRQKKLEMEKLQLQALEQEHKKLAAHLEEERGKNKHVVLMLVKECKQLSGKVVEEAQKLEEVMAQLEEEKKKTSELEEQLSAEKQRSSGMEAQLEKQLSEFDTEREQLRAKLSREEAHTTDLKEEIDKMKKMMEQMKKGSDGKPGLSLPRKTKDKRLASISVATEGPVTRSVACQTDVVTESTDPVKKLPLTVPIKPSTGSPLVPTNTKGNVGPSALLIRPGIDRQSSHSDLGPSPPTALPSSANRIEENGPSTGNAPDLSNSTPSTPSSTAPAAAQTPGTAPQNHSQAPTVHSLHSPCANTHPGLNPRIQAARFRFQGNANDPDQNGNNTQSPPSRDVSPTSRDNLVAKQLARNTVTQALSRFTSPQAGASSRLGVSPGGDAGTCPPVGRTGLKTPGAARVDRGNPPPIPPKKPGLSQTPSPPHPQLRASNAGAKVDNKIVASPPSTLPQGTKVVNEENVPKSSSPQLPPKPSIDLTVAPAGCPVSALATSQVGAWPAGTPGLNQPACSDSSLVIPATVAFCSSINPVSASSRSPGASDSLLVAASGWSPSLTPLLMSGGPAPLAGRPTLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLNAEARVDAADKNGFTPLCVAAAQGHFECIELLTAYNANINHSAAGGQTPLYLACKNGNKECIKLLLEAGTDRSIKTRDGWTPIHAAVDTGNVDSLKLLMYHRVRAHGNSLSSEEPKSGLFSLNGGESPTGPSKPVVPADLINHADKEGWTAAHIAASKGFKNCLEVLCRHGGLEPERRDKCNRTVHDVATDDCKHLLENLNALKIPLRISVGEIQPSNDVSDDFECEHTICTLNIRKQTSWEDFSKAVSQALTNHFQAISSDGWWSLEDGTFNNATDSCIGLGTSSIRSIMLGSMPWSTGQSFSQSPWDFLKKKKVEQVLALLSGPQEGCLSSVTYASMIPLQMLQNYLRLVEQYHNVIFHGPEGSLQDYIANQLALCMKYRQMAAGFPCEIVRAEVDSGFSKEQLVDVFIRNACLIPVKQFPVKKKIIVILENLEKSSLSELLGDFLAPLENRSTESPCTFQKGNGTSECYYFHENCFLVGTIAKACLQGSDLLVQQHFRWVQLRWDCEPIQGLLQRFLRRKVVSKFRGQLPAPCDPVCKIVDWALSVWRQLNSCLARLGTPEALLGPKYFLSCPVVPGHAQATVKWMSKLWNAVIAPRVQEAILSRASMNKQPGTGQTASKKYPSQGQQAVVRAALSILLNKAVLHGCPLPRAELDQQIADFKGGSFPLSIVSSYSKKKVESGAWRKVNTSPRKKPGHFSSPTWNKPDPKREGMRNKTIPHLNTNRNSSLSKQQSLENDLSVTLTLDHRLSLGSDDEADLVKELQSMCSSKSESDISKIADSRDDLRKFDSSRTNPGTSAPLNLRTPVPQKEASPPSSRQTAECSNSKSKTEMGVSSVKSFLPVPRSKVAQCSQNTKRNSSSSNTRQLEINNNSKEENWTLDKHEQVEKPNK
What is the function of this protein?
Regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurons, and thus controls dendritic spinogenesis and dendritic spine maintenance.
What are the official names of this protein?
Cortactin-binding protein 2, CortBP2.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Cell projection, dendritic spine. Note=Remains associated with dendritic spines even after glutamate stimulation.
Protein: PAN1_PODAN
Sequence: MYSNPNSFLGGNSQRPGQPQYGNQFGAGAGQPQLQQPGPFAPQPTGFGQQPALQQQYTGYPGLQAPQPTGQLQPQFTGFGQAPQQNVGAAAPPMPAMPQQFQQQFQQQQQQFQQQPQQTSSPFGAAPSQQPPASALAPPAPPMKPQPTGFHEMAASFQTAGGSKSTASAPRKTNKIPNIRLSFITAQDQAKFETLFKSAVGDGQTTMTGEKARDLLLRSRLDGDSLSHIWTLADTTRSGQLHFPEFALAMYLCNLKLTGKTLPEHLPENIKNEVSSMVDIINFSVAEEAANASDSGIRQNTATPPVIQHPQPQPSNSQLLQAQMTGFPSQQTGFLGAQPTGMPQATGYTGPRPPMPPMPTGFGSSLTPNAGPGGMVAPLNAQPTGIPGQWGLVNTPATGLPLIDALQARMMPQQGREQQTYTTAGLQGNAVIPWAITKDEKTRYDSLFRAWDGLHKGYISGDQAIEILGQSGLEKPDLERVWTLADNGNKGRLDMDEFAVAMHLIYRKLNGYPVPNQLPPELVPPSTRNFNQSIGMVKNMLHQESEYRKNSGAALLPQKTGVSYLKGHSFKGAGAGFGNRKDATVFKNNDEEVGYRSSARRRVGNNSPRPESPASVNSSEELSIEQLRKKIKEKQVLLDAMDFADEKHAEEDDILDRRDRREADELYRRIRRIQEDIDNHPDASLISADSDAERRALKRQLQNLTDKIPDLASQVRKTEKAIADARLELFRLRDAKAHPSSAAAIIGTGPGGTVTESDRLKARAKAMMQQRTAALTGKKIEVSNDDLDAPKRLEEESIKIRTEKENNERMVRDVEDSVREFAKGIEDNMKEGAQDSTTEHEKRRWEDGLGVEDEVRDFIYDLQRSSRAARIRSQDRQGGRQPTQEPTRAEAPPSARSVSPAVSRTSTPSAPVAGGGSYSSYKTPEERAAFIKQQAEQRMAERLAALGIKAPTKPGETAAQRMERERAERAAKLRQAEEEDARREAERQARIAEETGAPAPAAQAAVPKPEGKKPPPPPSRKTPKVDDRRAEEEAAARKAEEGRLERERGEQERQTRELEERAKDQEDELAKERAEADARLKALEEQVRQGKLKKEEEKRKKKAAMAEAKEQEAKLAQRRAEIEAARKREEELRKQLEALDVEDSSSDDDEGPEQITPQASTPTLGGSQVGGSQELEPAPPTPVPAPVQSPPQIVTSSPAETESRNPYFRMRAQAAETTPAPPAPPAPVAPPPPPQPDVSTNPFHRMTQAAAAPAPSGPVSRKRPEDDGWGSDKEDDDEDSDDDRPGQGAAHLASILFGTMAPPRPLSATGDKSAAASPPVTSPVASPPPAIPSPTAAGAPPAPPPPPPMPGMGAPPPPPPPPPMPGSGAPAAPPPPPPPAPGGAPPPPPPPPPPPGGAPAPAAPAGGRPAAFLGEIQAGRALRKTQTKDKSGAAVAGRVLD
What is the function of this protein?
Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis.  The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton.  Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins.  Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity).
What are the official names of this protein?
Actin cytoskeleton-regulatory complex protein PAN1.
What is the protein family that this protein belongs to?
Belongs to the PAN1 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, actin patch. Note=Cytoplasmic and cortical actin patches.
Protein: PHC2_MOUSE
Sequence: MENELPVPHTSNRASVTTNTSGTNSSSGCISSSGGGGGSGGRPTAPQISVYSGIPDRQTVQVIQQALHRQPSTAAQYLQQMYAAQQQHLMLQTAALQQQHLSSAQLQSLAAVQQASLVANRQGSTPGSSVSSQAPAQSSSLNLAASPAAAQLINRAQSVNSAAASGLAQQAVLLGNTSSPALTASQAQMYLRAQMLIFTPTATVATVQPELCTGSPARPPTPAQVQNLTLRTQQTPAAAASGPPPTQPVLPSLALKPTPSSSQPLPAPPQGRTMAQGSPAGAKPSGTDNAPETLKAGDGNCNMEGRPGPGRAVPAVATHPLIAPAYAHLQSHQLLPQPPAKHPQPQFVAQQQPQPPRPAPQVQSQPQLASVSPSLALQSSPEDHALPLGSVTQALPLQCSTTHVHKPGNSQQCHLPTLDTGSQNGHPEGGSHPPQRRFQHTSAVILQVQPASPVTPQQCAPDDWKEVVPAEKSVPVARPGPSPHQQAIIPAIPGGLPGPKSPNIQQCPAHETGQGIVHALTDLSSPGMTSGNGNSASSIAGTAPQNGENKPPQAIVKPQILTHVIEGFVIQEGAEPFPVGRSSLLVGNLKKKYAQGFLPEKPPQQDHTTTTDSEMEEPYLQESKEEGTPLKLKCELCGRVDFAYKFKRSKRFCSMACAKRYNVGCTKRVGLFHSDRSKLQKAGTTTHNRRRASKASLPTLTKDTKKQPSGTVPLSVTAALQLAHSQEDSSRCSDNSSYEEPLSPISASSSTSRRRQGQRDLDLPDMHMRDLVGVGHHFLPSEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKIYARISMLKDS
What is the function of this protein?
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development.  PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
What are the official names of this protein?
Polyhomeotic-like protein 2, mPH2, Early development regulatory protein 2, p36.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARLY_BACC4
Sequence: MSKLWGGRFTEEAEAWVEEFGASISFDQQLVNQDINGSMAHVTMLAKQGIVTQEEAEKIKIGLQYLLKEAKENKLQFSVEAEDIHLNIEKMLIEQIGEVGGKLHTGRSRNDQVATDMHLYLKEKVEHIIKATKQLQTVLVHQAENNIETIMPGYTHLQRAQPISFAHHILAYFWMLERDVNRYEDSLKRINISPLGAGALAGTTFPIDREYSAELLGFNGIYENSLDAVSDRDFILEFLSNSSMLMMHLSRFCEELILWSSQEFQFIEMSDQYATGSSIMPQKKNPDMAELIRGKTGRVYGNLFSLLTVMKGLPLAYNKDLQEDKEGMFDTVKTVEGCLHIMAGMLETMTVNKEKMGQAVTQDFSNATEIADYLANKGLPFRQAHEIVGKLVLYCTQKGIYLLDVSLETYKEMSSLFEEDLYEVLSPYAAVKRRNSAGGTGFEQIKNALEKAKGLTKEVIKG
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMO_JANMA
Sequence: MTNALQATPKIGFVSLGCPKALVDSEQILTQLRAEGYDTAKSYDGADLVIVNTCGFIDAAVQESLDAIGEALHENGKVIVTGCLGAKKDADGDDIIQKVHPKVLAVTGPHALGEVMDAVHKHMPKPHAPFIDLVPAQGIKLTPKHFAYLKISEGCNHRCSFCIIPSMRGDLVSRPIADVMMEAENLFKAGVKELLVISQDTSAYGVDVKFRMGFWNGKPVKTHMTQLVEALGELAKQYGAWVRLHYVYPYPHVDAIIPMMAEGKILPYLDVPLQHAHPDVLKRMKRPASGEKNIERIQAWRAMCPDLTIRSTFIAGFPGETDAEFEYLLDFLKEAEIDRLGCFAYSPVEGATANDLPNAVPEEVREERRGRVMLLQEEISKKRLQAKVGKTMRVLLDEVNRNGGVARSGADAPEIDGVVYVKPPYEPHLKLKVGEFIDVKITGADAHDLWAEA
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTMA_STAAC
Sequence: MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II CmtAB PTS system is involved in D-mannitol transport.
What are the official names of this protein?
Mannitol-specific phosphotransferase enzyme IIA component, EIIA, EIII, PTS system mannitol-specific EIIA component.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IL6_MACMU
Sequence: MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVLPGEDSKNVAAPHSQPLTSSERIDKHIRYILDGISALRKETCNRSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEDTCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPEPTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSNLRALRQM
What is the function of this protein?
Acts as an essential factor in bone homeostasis and on vessels directly or indirectly by induction of VEGF, resulting in increased angiogenesis activity and vascular permeability.  Induces, through 'trans-signaling' and synergistically with IL1B and TNF, the production of VEGF.  Involved in metabolic controls, is discharged into the bloodstream after muscle contraction increasing lipolysis and improving insulin resistance (By similarity).  'Trans-signaling' in central nervous system also regulates energy and glucose homeostasis.  Mediates, through GLP-1, crosstalk between insulin-sensitive tissues, intestinal L cells and pancreatic islets to adapt to changes in insulin demand (By similarity).  Also acts as a myokine (By similarity).  Plays a protective role during liver injury, being required for maintenance of tissue regeneration (By similarity).  Also has a pivotal role in iron metabolism by regulating HAMP/hepcidin expression upon inflammation or bacterial infection (By similarity).  Through activation of IL6ST-YAP-NOTCH pathway, induces inflammation-induced epithelial regeneration (By similarity).
What are the official names of this protein?
Interleukin-6, IL-6.
What is the protein family that this protein belongs to?
Belongs to the IL-6 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: VEMP_CVBQ
Sequence: MFMADAYFADTVWYVGQIIFIVAICLLVIIVVVAFLATFKLCIQLCGMCNTLVLSPSIYVFNRGRQFYEFYNDVKPPVLDVDDV
What is the function of this protein?
Plays a central role in virus morphogenesis and assembly.  Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport.  Also plays a role in the induction of apoptosis.
What are the official names of this protein?
Envelope small membrane protein, E protein, sM protein.
What is the protein family that this protein belongs to?
Belongs to the betacoronaviruses E protein family.
What are the subcellular locations of this protein?
Host Golgi apparatus membrane; Single-pass type III membrane protein. Note=The cytoplasmic tail functions as a Golgi complex-targeting signal.