PharMolix/UniProtQA huggingface dataset:
Protein: YIDC_LEGPA
Sequence: MDIRRIVLYMALALIGLSLWNAWQIDYPAKQPVEEKTASQLTSDGHLLPQIIPSNAEQPITLKAEEKASSSKQLIQVKTDVLDVDIDLKNGDIVKGLLLDYPLSVEDKNKPFPLLQNQASQRYVANSSLFILDGQTPQSLDFDFTSEKEYYELKSDQNQLIVTLNGKSEDGLDVKKEFVFTKGSYLIEVNYKIANTGNSLWKGYFNTQLLRSSPKEDKSSIFHIGSYTGASFSNPGKNRYQKVSFSDMSKSNLDVDAKGGWIAMQQHYFLSAWVPNADSENKFYTLATDKDYTIGAVSQPITVKPKEDKIVGSKLYIGPEITSVLKGISPSLDLTVDYGILWFLSSLLFSLMKAIYTVVGNWGWSIVLVTVLIKLAFYRLSATSYKSMASMRKLQPKLQALRERYGDDKAKISQATMELYKQEKVNPLGGCLPILIQIPVFIALYWVLLESVELRQAPFIFWINDLASADPYHVLPLIMGATMLIQQKLNPAPADPMQAKVMMFLPILFTGLFWNFPSGLVLYWIVNNTLSILQQWYITRKYSDEKPAKKVVATAK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RNPH_CAUSK
Sequence: MRPSERAPDVLRVVTLETGVNRYAEGSCLISFGHTKVLVTATVEENVPGWMRNKGAGWVTAEYGMLPRATHTRGRREAALGKQSGRTQEIQRLIGRSLRAVVDLKALGERQISLDCDVLQADGGTRTAAITGAWVALRIAVNYLLEEGVLKTDPIVGQVAAVSCGVFKDTPVLDLDYEEDSQAEADSNFVLTNVGDIVEIQATGEKRGFTRGEFEQLFALAEKGIGELFVKQLEAVSAAKPR
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: HLDE_RHOPB
Sequence: MLDFEAVLPAIGRQTVLCVGDLMLDEFVYGEVSRISPEAPAPVIAVQRSEINVGGAGNVARNIAALGARCIFVGLIGDDAAGRTLSAALAAEPLIEPVLVCDESRPTTRKVRFVSAHFSTHMLRADWEIAAPASLMVEQQLIDAILQQLPAADIVLLSDYAKGVLTARLIREVIDAARKLNKRVIVDPKSPNFALYRGATLLTPNRKEFAEATRSRADSQAEIAASAREAIAVADCEAILVTQSEQGMTLVPRDGEAIHVPAHPVKVRDVSGAGDTVAAVLAVMLAAGADWDVALRAANAGAAVAVSKNGTASVTLGELRRKVLPPASLAAEEKIVAAGGDLEPHLVEWRAEGLRIGFTNGCFDILHPGHVKVLTAARGACDRLIVGLNSDASVKRLKGESRPVQDERARAEVLAALEAVDLVVIFEEDTPLQLITRIVPSVLVKGGDYTREQVVGHEIVAAQGGEVVLVDILPGHSTTTLVARAQNGKA
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: GBLP_BIOGL
Sequence: MTEQMTLRGTLQGHGGWVTQIATTPQYPDMILSASRDKSLIVWRLTRDESSYGVPQKSLHGHGHFVSDVILSSDGQFALSGSWDHTLRLWDLSTGQTTRRFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIQDDCHTDWTSCVRFSPNTQNPIIVSSGWDRLVKVWNLTNCKLKTNHYGHTGYVNTVTVSPDGSLCASGGKDSQAMLWDLNEGKHLYTLDGAGDTINALCFSPNRYWLCVASGPSIKIWDLEGKVVVDELKPEVMGTTSKAPTCLSLAWSADGQTLFAGYTDKLIRVWQVSMVSR
What are the official names of this protein?
Guanine nucleotide-binding protein subunit beta-2-like 1, Receptor of activated protein kinase C, RACK.
What is the protein family that this protein belongs to?
Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.
Protein: MIM1_NEUCR
Sequence: MSAEEISNPLAESGVTISSDSEQYSAPESASPQSPSSSSPAVVLYQPPTVWSLFRSAVINLFLPFVNGMMLGFGELFAHEAAFRLGWSNTKVFPVSRRDARPIGPGVEVVERPRRRVDLDDHLDELTSLE
What is the function of this protein?
Required for the assembly of the TOM (translocase of outer membrane) receptor complex, which is responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins.
What are the official names of this protein?
Mitochondrial import protein 1.
What is the protein family that this protein belongs to?
Belongs to the MIM1 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane.
Protein: RL13_SHIFL
Sequence: MKTFTAKPETVKRDWYVVDATGKTLGRLATELARRLRGKHKAEYTPHVDTGDYIIVLNADKVAVTGNKRTDKVYYHHTGHIGGIKQATFEEMIARRPERVIEIAVKGMLPKGPLGRAMFRKLKVYAGNEHNHAAQQPQVLDI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: BUD4_YEAS7
Sequence: MHDAESTVDSLLKEIDNEMEQTKSNITQNGSEDTPHNWKLPLQEIGDDTMEMLVKHNTRSNATENSRGRSPSKMSTISNESLNLGLLRVNSELEESPAAVHQERIKNSVANGALGHANSPKVLNNLKNMAQDIDKLARDEEKPVKLSSSPLKFTLKSTQPLLSYPESPIHRSSIEIETNYDDEDEEEEDAYTCLTQSPQILHSPSRIPITNAVSINKLNLDFTLNPNESDKSLVSDTSVDSTGRELDTKTIPELPFCMSSTPEMTPVDEKCNLPSKLLNTSNNSHSDSRSPTASVEDLNISTNLPGADSSQNNPVTTDADALIENDVVRDLQQNMEHIDDAFDEKKVLDEGCSNEPVTFLGENDTRSIVYSNKGTNANVQEFSQEDSLAHSEPNFKDLNATSDDVWNEDKETDANISTSTKSEESYIADYKVTRQEDWDTKKLHQESEHANEQPAIIPQKDSSEETFTELNNESEFQRNSKDGEEYRIVQHEESLYGQRTKSSEENIINGSEIGVDHGEADEVNEPLAKTSAEEHDLSSSCEDQSVSEARNKDSIEEKEVETKDENIETEKDESEYHKVEENEESEHVPLLPPLPRWEEIQFNEPFIDENDTSNDSIDLTRSMKPSDYISIWHIQEEEIKSNSPESIANSQFSQQSSITTASTVDSKKDNGSTSFKFKPRIVSRSRIYNPKSRVSSLNYYDNEDYILSNSEWNALDPMRRNTLISKRIQDNIRTQKGHAPLIRPSVMKLNGEDSGFQNHFLEVEQPQEHENIPLSTHLSEQDITTNVGLDEQKLPTNTQDEAEISIREIESAGDITFNRGDLLSLSFDEELGQDFANFLDALDHDSTSFNHGPDDSSSFQRDSSKKSFNSLWESSYELKPPPSIRKQPIAPDVLQKLLESDTKDDADLEKIREERITEPRTGLGIGMLKTPVKDVSIALAASIKGYEASFSDTDSRPEGMNNSDAITLNMFDDFEEDKMTPSTPVRSISPIKRHVSSPFKVVKAGNKQENNEINIKAEEEIEPMTQQETDGLKQDIPPLLAQTKDNVEAKEETITQLEEPQDVEQEFPDMGTLYLSIKAISTLALYGTKSHRATYAIVFDNGENVVQTPWESLPYDGNIRINKEFELPIDFKGKAETSSASSERDSYKKCVITLKCKYEKPRHELVEIVDKVPVGKSFFGKTKYKFEKKYVQKKPKQDEWDYLFAQDGSFARCEIEINEEFLKNVAFNTSHMHYNMINKWSRIADKIHGSKRLYELPRKAPHKVASLDVEACFLERTSAFEQFPKQFSLVNKIVSKYKLQQNIYKEGYLLQDGGDLKGKIENRFFKLHGSQLSGYHEISRKAKIDINLLKVTKVLRNEDIQADNGGQRNFTDWVLFNECFQLVFDDGERITFNAECSNEEKSDWYNKLQEVVELNVFHQPWVKKYCEKLAEEEKTRTTGHNLKQDFN
What is the function of this protein?
Required for establishment of the axial budding pattern in haploid cells.  Cooperates with other bud site selection proteins to recognize a spatial landmark during mitosis and they subsequently become a landmark for downstream polarity establishment factors that coordinate axial budding and cytokinesis.  Involved in the septin organization at the bud neck (By similarity).
What are the official names of this protein?
Bud site selection protein 4.
What is the protein family that this protein belongs to?
Belongs to the BUD4 family.
What are the subcellular locations of this protein?
Bud neck. Note=Localizes to two distinct rings on either side of the mother-bud neck. The rings stay present in cells after cytokinesis and disappear before the next bud emergence. Requires IQG1 for proper localization (By similarity).
Protein: CRCB2_THEFY
Sequence: MSWPVLAAVAAGGALGALARAGLLAATPQHPATADWGTVLVNVLGCALIGVLMETLTRRPNPHPLLRPFLGVGVLGGFTTFSAAITDATDAFAAHQPGEALLAIAANLIGALLAVSAAAGATATLLDRAAQRKKT
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 2.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TVB5_MOUSE
Sequence: ILLCAKHMEAAVTQSPRSKVAVTGGKVTLSCHQTNNHDYMYWYRQDTGHGLRLIHYSYVADSTEKGDIPDGYKASRPSQENFSLILELASLSQTAVYFCASSGTGGALDTQYFGPGTRLLVL
What are the official names of this protein?
T-cell receptor beta chain V region C5.
Protein: PKHA2_MOUSE
Sequence: MPYVDRQNRICGFLDIEDNENSGKFLRRYFILDTQANCLLWYMDNPQNLAVGAGAVGSLQLTYISKVSIATPKQKPKTPFCFVINALSQRYFLQANDQKDLKDWVEALNQASKITVPKAGTVPLATEVLKNLTAPPTLEKKPQVAYKTEIIGGVVVQTPISQNGGDGQEGCEPGTHAFLRRSQSYIPTSGCRPSTGPPLIKSGYCVKQGNVRKSWKRRFFALDDFTICYFKCEQDREPLRTIPLKDVLKTHECLVKSGDLLMRDNLFEIITTSRTFYVQADSPEDMHSWIEGIGAAVQALKCHPREPSFSRSISLTRPGSSTLTSAPNSILSRRRPPAEEKRGLCKAPSVASSWQPWTPVPQAEEKPLSVEHAPEDSLFMPNPGESTATGVLASSRVRHRSEPQHPKEKPFVFNLDDENIRTSDV
What is the function of this protein?
Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides.  May recruit other proteins to the plasma membrane.
What are the official names of this protein?
Pleckstrin homology domain-containing family A member 2, PH domain-containing family A member 2, PH domain-containing adaptor PHAD47, Tandem PH domain-containing protein 2, TAPP-2.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein. Nucleus. Note=Locates to the plasma membrane after treatments that stimulate the production of PtdIns3,4P2.
Protein: DEOD_BACMK
Sequence: MSVHIEAKQGEIAESILLPGDPLRAKYIAETFLEDVTCYNNVRGMLGFTGTYKGKRVSVQGTGMGVPSISIYVNELIQSYGVKNLIRVGTCGAIQKDVKVRDVIIAMTACTDSNMNRLTFPGFDFAPAANFDLLKKAYDAGTEKGLHVRVGNVLTADVFYRESMDMVKKLGDYGVLAVEMETTALYTLAAKYGVNALSVLTVSDHIFTGEETTSEERQTTFNEMIEIALDAAIQQ
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: ATPB_STRPC
Sequence: MSSGKIAQVVGPVVDVMFASGDKLPEINNALIVYKDSDKKQKIVLEVALELGDGMVRTIAMESTDGLTRGLEVLDTGRAISVPVGKETLGRVFNVLGETIDLEEPFAEDVDRQPIHKKAPSFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVGKTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEPPGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTQKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLTQMGIYPAVDPLASSSRALSPEIVGEEHYAVATEVQRVLQRYRELQDIIAILGMDELSDEEKTLVGRARRIQFFLSQNFNVAEQFTGLPGSYVPVAETVRGFKEILEGKYDDLPEDAFRSVGPIEDVIKKAEKMGF
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TRPD_TOLAT
Sequence: MTVSLEGLYRGESLTSEQTEQLFGELLRGEMDPIVLSSLLTAMKVKGESPSEIEGAARALIAAAKPFPRPDYEFCDIVGTGGDGLYTINISSTAAIVGATCGIKVAKHGNRSVSSKTGSSDLLEKLGIKLDMSPETARHCLDEANICFLFAPHYHSGMRFAAPVRQALKTRTIFNVLGPLINPARPTYQLMGVYSPDLLEPIAETLHALGLKKGMVAYGSGLDEIAVHGETQVAEINDGHIRYYTLTPTDFGLKYYPLESIQGGTPDENRKITETLLAGKGTDAQQAAIAINLAPLLKMGGLVDTLKQGAEMAIETLRSGDALDKVTQLATLSHKE
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: EFTS_AEDAE
Sequence: MIFTRLTRFVGHGTGLRLYATAEKSSLATLRKKTGYTFANCKKALEMHNNDLAKAEQWLQEQAQAMGWSKATKLEGRNTTQGLIGIMVKNNIGAMVEVNCETDFVARNQSFQKFVQAASTACVRYMDQIEGDANLTKVGLNSESLKQIKLEDGKSLADHLALMIGTVGENASLNRAICFKAPESINLTGYVHPAPTEEVPLDVPQFGKYGSILAFKHTSADSNGEVAKKVCQHVVGMKPAKIGDKTRDEPAKDKDDETCLIYQEYLADPSYTVAEVLEANNVEVVDFQRFECGEKIKMDDETVRAVN
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, mitochondrial, EF-Ts, EF-TsMt.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: KOZA_XENLA
Sequence: MSKLRTEDMSHPVKPLRSFLIQDILSHMGPGSKEKSLGFPKTDQDQDSSLRDTEEKYASEKLQSSSQPAEIHHSHMEADENLELDTAQPITAVENKLAKQQQKRSRAAFSHSQVIELERKFSSQKYLSAPERAQLAKSLKLTETQVKIWFQNRRYKTKRKQLATDMEEVEKSSAHPAQCRDTNISRTSLLSFYQNYQRYPYLYYLAGWPAPLW
What is the function of this protein?
May regulate cell proliferation in a tissue-specific manner.
What are the official names of this protein?
Homeobox protein koza, Homeodomain transcription factor koza.
What is the protein family that this protein belongs to?
Belongs to the NK-3 homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: IF4E_RABIT
Sequence: MATVEPETTPTPNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV
What is the function of this protein?
Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.  In addition to its role in translation initiation, also acts as a regulator of translation and stability in the cytoplasm (By similarity).  Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression: in the complex, EIF4E mediates the binding to the mRNA cap.  Component of a multiprotein complex that sequesters and represses translation of proneurogenic factors during neurogenesis (By similarity).  In P-bodies, component of a complex that mediates the storage of translationally inactive mRNAs in the cytoplasm and prevents their degradation (By similarity).  May play an important role in spermatogenesis through translational regulation of stage-specific mRNAs during germ cell development (By similarity).
What are the official names of this protein?
Eukaryotic translation initiation factor 4E, eIF-4E, eIF4E, eIF-4F 25 kDa subunit, mRNA cap-binding protein.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic initiation factor 4E family.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Cytoplasm. Cytoplasm, Stress granule. Nucleus. Note=Interaction with EIF4ENIF1/4E-T is required for localization to processing bodies (P-bodies). Imported in the nucleus via interaction with EIF4ENIF1/4E-T via a piggy-back mechanism.
Protein: PURL_SYMTH
Sequence: MSEMQQPWSLVGLTEAEYRRVVEILGREPNPTELHMFGVMWSEHCAYKHSKAALRRLPTRGEHVLQGPGENAGVVRIDDDLAVAFKLESHNHPSFVDPFNGAATGVGGILRDVFTMGARPVATLNSLRFGPLDEPKQRELLRGVVAGIGHYGNTVGVPCIGGEVYFDESYRGNCLVNAMCIGILRPDRIHRGIAAGPGNAIMVVGNPTGRDGIHAASLLASAEFSGSEAEAALPTVPVGDPFAEKMLMEACLELFETDAVVGIQDMGAAGLISSSSEMAARGGVGVELDVRKVPAREEGMEPWEFLLSESQERMLVCVKKGREAEVEAICRKWGVGCAVIGRVTDDGMVRVLDDGRVVAEVPARALAEAPVYHPAKAEPAYLAELRAFDWSRLPEPEDWNETLLRLLGSPNIGARAWIYEQFDHMVQAGTVLGPGGDAGVIRLGAAVAPGAHGLTRQPPGEGLPGRSGQAGPPKGIAASVDCNGRYVYLNPRRGTAIAVAEAARNCVVTGARPVAITNNCNFGNPEKPEIFWTFDEAITGMAEACEALGTPVTGGNVSFYNETSGEAIHPTPTIGMIAVHENLDRLTTPGFKQVGDVILLLGETRDELGGSEYARLIHGVLAGDAPALDLAFEKRLQDVVLRAIHEGLVTAAHDVAEGGLAVALAEMAIAAAEPSLGCQVSIFLGEGRVDGQLFGESQSRILVTATREQVGRLQALLMVEQIPFRVLGDVTADGRFRLAALAPGSGSAHVYRRQELIDLPVADLVRAHKEAIPRWMDA
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSPA_STRT1
Sequence: MRKVAIPVAILALIGLDQWVKHWVVANISLNQVIKAIPGVFSLTYLQNRGAAFSILQNQKYFFVILTVLVIGAALFYLVKNYQKSLWLVLSLILIISGGIGNFIDRVHLGYVVDMVQLDFIDFAIFNVADSYLTVGVLLLILILWKEENGSHH
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRMB_PSESM
Sequence: MTDTHVPPPELPAAEEGEERPHRRIKSFVMRAGRMTEGQQRGLDQGRPLFGLSLTDTPVDFDQVFGRSAPRTLEIGFGMGHSLLEMAAASPEQDFIGVEVHYPGVGAMLNGVLTQGLTNVRVYDCDAIEVLNRCIADNSLDRLMLFFPDPWHKSRHHKRRIVQPEFAALVRSKLKVGGVFHMATDWGPYAEYMLEVMSVAPGYRNQAEDNQYVPRPAERPITKFERRGEKLGHGVWDLKFEKVD
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: PNCB_CUPNH
Sequence: MIIPSLLDTDLYKFTMMQVVLHQFPQAQVEYRFKCRNAGVDLTPYIDEIRAEVAHLCQLRFTDDELAYLRGLRFIKSDFVDFLGLFHLNEKYVSVRPSPQGNGEIEISIIGPWLHTILFEVPVLAIVNEVYFRRTQPRPDLAEGRRRLDQKLALLKTPELADCVIADYGTRRRFSREWQEEVLLTMRRLLGPQLAGTSNVHFARLHNMVPLGTMAHEYLQACQALGPRLRDSQVYALERWAREYRGDLGIALSDTYGFDAFLRDFDLYFCKLFDGVRHDSGDPMLWGERMVAHYAANRVDPRTKTLIFSDSLDIPRVIELYERFHGRCRLAFGVGTNLTNDLGYTPLQIVIKMVRCNGQPVAKLSDTPEKTMCDDPGYLSYLRQVYSVQPAA
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: EFP_LEIXX
Sequence: MASTADIKNGIVINIDGQLWSVIEFQHVKPGKGGAFVRTKLKNVTTGKTVDRTYNAGAKIDITNVDRRDYQYLYQDGADFVFMDTSDYDQITIPGPIVGDAANFMLENQNVTVALHEGSPLYVELPASVVLEITYTEPGLQGDRSTGGTKPATVQTGYQIQVPLFLETGTKVRVDTRTGDYLGRVND
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_BRUMB
Sequence: MNKPKNSPARKMIAENRKARFNFEILDTLEAGLVLTGTEVKSLRANQANIAESYASFEDGEFWLINSYIPEYTQGNRFNHEPRRLRKLLVSRREMSRLFNSVSREGMTVVPLKLYFNDRGRAKLELALARGKKTHDKRETEKKRDWNREKARLLRDRG
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: EUTC_PSEPW
Sequence: MDRQIPTPENPWLALRNLTPARIALGRSGISLPTSAQLDFQFAHAQARDAVHLAFDHTALSEQLKERGRDSLVLHSAASDRNQYLQRPDLGRRLNERSVEQLRQHAKTNPGGCDLAIVVADGLSALAVHRHTLPFLARFEEQAAADGWTSAPVVLVEQGRVAVADEVGQLLGARMTVMLIGERPGLSSPDSLGLYFTYAPKVGLTDAYRNCISNVRLEGLSYGMAAHRLLYLMREACRRQLSGVNLKDEAEVHTIDSENTSNQKGNFLLGEG
What is the function of this protein?
Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds.  Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
What are the official names of this protein?
Ethanolamine ammonia-lyase small subunit, EAL small subunit.
What is the protein family that this protein belongs to?
Belongs to the EutC family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: ZGPAT_HUMAN
Sequence: MDEESLESALQTYRAQLQQVELALGAGLDSSEQADLRQLQGDLKELIELTEASLVSVRKSSLLAALDEERPGRQEDAEYQAFREAITEAVEAPAAARGSGSETVPKAEAGPESAAGGQEEEEGEDEEELSGTKVSAPYYSSWGTLEYHNAMVVGTEEAEDGSAGVRVLYLYPTHKSLKPCPFFLEGKCRFKENCRFSHGQVVSLDELRPFQDPDLSSLQAGSACLAKHQDGLWHAARITDVDNGYYTVKFDSLLLREAVVEGDGILPPLRTEATESDSDSDGTGDSSYARVVGSDAVDSAQSSALCPSLAVVGSDAVDSGTCSSAFAGWEVHTRGIGSRLLTKMGYEFGKGLGRHAEGRVEPIHAVVLPRGKSLDQCVETLQKQTRVGKAGTNKPPRCRGRGARPGGRPAPRNVFDFLNEKLQGQAPGALEAGAAPAGRRSKDMYHASKSAKRALSLRLFQTEEKIERTQRDIRSIQEALARNAGRHSVASAQLQEKLAGAQRQLGQLRAQEAGLQQEQRKADTHKKMTEF
What is the function of this protein?
Antagonizes the transcription repression by isoform 1 by competing for the binding of the NuRD complex.  Does not bind DNA.
What are the official names of this protein?
Zinc finger CCCH-type with G patch domain-containing protein, G patch domain-containing protein 6, Zinc finger CCCH domain-containing protein 9, Zinc finger and G patch domain-containing protein.
Protein: SC61G_NEUCR
Sequence: MADQIQEILDVPREFLKDGIQFIKKCQKPDRREFIKISQAVGTGFLIMGAVGYLVKLIHIPLNQVLVGGA
What is the function of this protein?
Necessary for protein translocation in the endoplasmic reticulum.
What are the official names of this protein?
Probable protein transport protein Sec61 subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the SecE/SEC61-gamma family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: ZNUC_PSEE4
Sequence: MSDALIRLEQVGVSFAGEAVLDSIDLAVAPGQIVTLIGPNGAGKTTLVRAVLGLLKPHRGKVWRKPKLRIGYMPQKIQVDATLPLSVLRFLRLVPGVDRAAALSALQEVGAEQVIDSPIQTISGGEMQRVLLARALLREPELLVLDEPVQGVDVVGQTELYNLITRLRDRHGCGVLMVSHDLHLVMSATDQVVCLNRHVCCSGHPEQVSNDPAFVELFGQNAKSLAVYHHHHDHSHDLHGSVIAPGAHVHGEHCKHG
What is the function of this protein?
Part of the ABC transporter complex ZnuABC involved in zinc import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Zinc import ATP-binding protein ZnuC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.