PharMolix/UniProtQA huggingface dataset:
Protein: TMPS7_MOUSE
Sequence: MDKEKSDPSCKSSDLKISNISIQVVSVPGKLPGRRPPRKPIGKPRPRKQPKKRAPFWNVQNKIILFTVFLFILAVTAWTLLWLYISKTESKDAFYFVGMFRITNIEFLPEYRQKESREFLSMAKTVQQVVNLVYTTSAFSKFYKQSVVADVSSNNKGGLLVHFWIVFVMPHAKGHIFCEECVAAILKDSIQTSIINRTSVGSLQGLAVDMDSVVLNAGLRSDYSSAVGSDNGCSRYLYADHLTLRYPLEISATSGQLMCHFKLVAIVGYLIRLSIESIQLEADNCITDSLTVYDSLLPIRSAILYRICEPTRTLMSFVSTNNLMLVILKSPYVRRLAGIRAYFEVIPEQKCESTILVKEINSFEGKISSPYYPSYYPPKCKCTWTFQTSLSTLGIALKFYNYSITKKSAKGCEHGWWEINEHMYCGSYMDHETIFRVPSPLVHIQLQCSSRLSDKPLLVEYGGYNISQPCPAGSFRCSSGLCVPQAQRCDGVNDCFDESDELFCVTVKPACNSSSFRQHGPLVCDGFRDCEDGQDEQNCTRSIPCTSRTFKCGNDICFRKQNAQCDGIVDCPDGSDEEGCGCSRSSSFLHRIVGGSDSQEGTWPWQVSLHFVGSAYCGASVISREWLLSAAHCFHGNRLSDPTPWTAHLGMYVQGNAKFISPVRRIVVHEYYNSQTFDYDIALLQLSIAWPETLKQLIQPICIPPAGQKVRSGEKCWVTGWGRRHEADSKGSPVLQQAEVELIDQTVCVSTYGIITSRMLCAGVMSGKSDACKGDSGGPLSCRRKSDGKWILTGIVSWGHGCGRPNFPGVYTRVSSFVPWIHKYVPSLL
What is the function of this protein?
Serine protease which preferentially hydrolyzes peptides with Arg at the P1 position.
What are the official names of this protein?
Transmembrane protease serine 7, Matriptase-3.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: LRC47_MOUSE
Sequence: MAAAAMAVSEAWPELELAERERRRELLLTGPGLEERVKAAGGRLPPRLFTLPLLHYLEVSGCGSLRAPGPGLAQGLPQLHSLVLRRNALGPGLSPELGPLPALRVLDLSGNALETLPPGEGLGPAEPPGLPQLQSLNLSGNRLRELPADLARCAPRLQSLNLTGNRLDAFPPELFRPGALPLLSELAAADNCLRELSPDIAHLASLKTLDLSNNQLTEIPAELADCPKLKEINFRGNRLRDKRLEKMVGGCQTKSILEYLRAGGRGGRSKGRQEASEKEDRKKRRERKQHRESGEGEEEVADSARLMLKVLHVSENPTPLTVRVSPEVKDVRPYIVGAIVRGMDLQPGNALRRFLNSQTKLHDDLCEKRTAATIATHDLQAVRGPLLYAARPPEDLKIVPLGRKEAKAKELVRQLQLEAEEQRKQKKRQSVSGLHRYLHLLDGKENYPCLVDAEGDVISFPPITNSEKTKIKKTTCNLFLEVTSATSLQLCKDIMDSLILRMAELSKSTSENKEEDMLSGTEADAGCGLSDPNLTLSSGKDGQCPLVVEQVRVVDLEGSLKVVYPSKTDLITLPPHVTVVR
What are the official names of this protein?
Leucine-rich repeat-containing protein 47.
Protein: TEFF2_MOUSE
Sequence: MVLWESPRQCSSWTLCEGFCWLLLLPVTLLIIARPVKLAAFPTSLSDCQTPTGWNCSGYDDRENDLFLCDTNTCKFDGECLRIGDTVTCVCQFKCNSDYVPVCGSNGESYQNECYLRQAACKQQSEILVVSEGSCATDTGSGSGDGVHEGSGETSQKETSTCDICQFGAECDEDAEDVWCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI
What is the function of this protein?
May be a survival factor for hippocampal and mesencephalic neurons.  The shedded form may up-regulate cell proliferation (By similarity).
What are the official names of this protein?
Tomoregulin-2, TR-2, Transmembrane protein with EGF-like and two follistatin-like domains.
What is the protein family that this protein belongs to?
Belongs to the tomoregulin family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: ATPF_ALKMQ
Sequence: MQGLVEFVLSNFIFTLINLWIMYWVLKKFLFKPTTEYMEGRKKSIADSIQEAEMKNKEADESKAQYDMKLQDIKKERSQIIDEATKRAEKRGDEIIKAAEDEAEKVIERAMTEIQREKQKSLNEMKNEISQLAIAAATKVIEKDLDEGTHHKMIQQFIDEVGETKWQN
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: DTDA_PYRNV
Sequence: MYVVVLSLGDPVSRTFLELVPEMPLVETRGEIEVRKFGEWPAVVHKGEPTDFNREDLLLSLGKYAIFISRHEMANPRPMFTVHTPGSWPDVSVANPPLATAIFRALCRHAEEPFKCAFEATHHPPNTSAASATFVEVGSTEAEWRDRRAVGVLVQALEEVLGRELGAGATTMVVGDLHYSTVADSALNGEVELGHILPKYLETTLQHVKTAFYKHTTPVRRVVVFRKNVKNPARAEVVEFLREREVEVVLKG
What is the function of this protein?
D-aminoacyl-tRNA deacylase with broad substrate specificity.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, D-tyrosyl-tRNA(Tyr) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DtdA deacylase family.
Protein: CHO2_KOMPG
Sequence: MVKESKFSYNSKDEKKYSLGKTFRGDIFNVPETHDMVRSLFDPTVKKSVSDYLIVLSLFINGIVYYYSPVTWRIPVFIVLYSFWRLGYNLGIGILLYKQSKSHSMFHWLKQIQINGGWAKKFVELELSSKLNAQQLNSVPDEFKTWIVFRSLVNLILMNDFTTYMCLVFACSDGAFNQSLSLIFLRWVLGISFFIFNIIVKLNAHLIVKDYAWYWGDFFFRLHNNEELIFDGVFDLAPHPMYSIGYAGYYGCALMTKSYTVLIMSIFGHLLQFLFLNYVETPHIEKIYGDDNLSENTISVNKRDDSVFIGTGGKPLVMLTKNFNWLRTNDIFTVVLALYASIVPIFLPASYNNSIIILAIVVKIGTSFVLNSVLYLQSRFKSWTLSFIKNYGTINISILDNKELLERLSFQNWTLLQNNTLVLNYSMLFTISVREVMYNEKFWQTEWLPLRFILAALMILGQFLTVHQMIDSIGLFGWYYGDFFIGVLSSHKSEVTTLSRSGIYHFLNNPERVTSNLTVWALYLLFNNSNKIFLVIALLFTMNNLIVLNFIEKPHMVKLYGEQNVLKHTSGIEKSINSLFLPNHVQGTIVKLSGSIDKVIQDSSKVIDEFIRNKHNQKPKELSLKKRRNSFQQVIELIRGSTDDTLTINLQELNDQGQLQLLNLLRKDDTDFYNLGDPIKVEWNMEDHKGKDKAWIGLYNIFQTSETRTKTLVSSKGYWIPIHREKYINLSDKIRNEEDCILEDELNRGVVQFSAELLPWVPGTYELRLHANEKHEVLAISKPFDIVVKKIDVPTSDDIGDERLEDFANKLYQGFVSKLFPAVESIEDESNWFLQMHIKENARQVEKLCSTLSQSCGVHLTKKAIVDEKCLKDLSFKISKLRKMLDELML
What is the function of this protein?
Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME).
What are the official names of this protein?
Phosphatidylethanolamine N-methyltransferase, PE methyltransferase, PEAMT, PEMT.
What is the protein family that this protein belongs to?
Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ATPB_SCIME
Sequence: MRINPTTSDSTVSTLEEKNLGRIAQIIGPVLDVVFPPGKMPNIYNALVVKGRDTVGQQINVTCEVQQLLGNNRVRAVAMSATDGLTRGMEVIDTGAALSVPVGGATLGRIFNVLGEPVDNLGPVDTRTTSPIHRSAPAFIQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEKNIAESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPRIVGEEHYETAQRVKQTLQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFQLILSGELDGLPEQAFYLVGNIDEATAKAMNLEGEKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: RR8_TRICV
Sequence: MVTDTISDMLTRIRNANMIKHQIVQIPATKMSKAITNILKEEGFIEDYEIYMENSYQFLLISLKYKGKSREPVICKMVRVSKPGLRVYSKSKKLPKVLDNLGIAIISTSKGVMTNLKAKELGIGGEVLCYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LPTD_HAEDU
Sequence: MKIRYSVLSTFIISALYSQDTQANLKHQCLLRVPHFAGEEITADQLNMPIEIEADRAVINQPKEANYSGNVTIKQGNRSIFADNVRIEQQAPQHRKAFLIGRYQYQDNLIQAEGHNALLDLQSKDAEVANTTYQLVGRQGRGEAESGQFTPQTRRLKNASFTACLLNDNAWSIEANEMVQHIKAGYAEMWHARFKIFDVPIFYSPYLQFPLGDQRRSGILTPKLYHSTKDGLIYSQPFYWNIAPNMDATFTSNYYSRRGWQINPEFRYLTALGQGILAGEYLANDRLDTYRPKDMNDRRYLFHWRHNMSFLTDWHLDVDYTNVSDRRYFSDFDSSYGNVTDGYALQHFKLGYYQPQYNLSISGKDFHTFDSFDNVKPYRVLPQIDFNYYQDQFLKDSRFSFFAQIARFENDSKSMPNAWRFHAEPIINIPFVNHYGSLNFETKLYASHYQQQKGENQTAEEVKKQLTRIIPQVKLDFQTVLEADKSLFSGFKQILEPRLQYVYRPYRDQSEIGSKSHESVGLGYDSALLQTDYYSLFNDRRYSGLDRISSANLITAGASTRFFNKKTGEEVFNISVGQTYYLRPSRVDSLAIDSTADRSSSWSVESNWRFQPKWNWHASYQYDTRLHKSSLANMSLQYKPSTENVFQLNYRYVNEDYINQNLSFNRYGQDIKQIGGMIGWNLTDKVAIMASHYRDIALKKAVETQLSLNYNTCCWSANLYVARQLTTTPIGAKDSIRNFYYDNKFGINFELRFGHDYSSGMHKMLSKGILPYVEQYGIN
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: RL1_AGRVS
Sequence: MAKLAKRIQKIREGVDPTKLVALSDAISMVKERAVAKFDETIEIAMNLGVDPRHADQMVRGVVNLPNGTGRDVRVAVFARGAKADEARAAGAEVVGAEDLVEIVQGGKIDFDRCIATPDMMPLVGRLGKVLGPRGMMPNPKVGTVTMDVAGAVKASKGGAVEFRVEKAGIIHAGIGKASFEAKALEENIKAFADAVIKAKPAGAKGNYVKRVAISSTMGPGVKIDPSSVTA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: RPOC2_ARATH
Sequence: MAERANLVFHNKVIDGTAIKRLISRLIDHFGMAYTSHILDQVKTLGFQQATATSISLGIDDLLTIPSKGWLVQDAEQQSWILEKHHHYGNVHAVEKLRQSIEIWYATSEYLRQEMNPNFRMTDPFNPVHMMSFSGARGNASQVHQLVGMRGLMSDPQGQMIDLPIQSNLREGLSLTEYIISCYGARKGVVDTAVRTSDAGYLTRRLVEVVQHIVVRRTDCGTIRGISVSPRNKNRMMSERIFIQTLIGRVLADDIYIGSRCVAFRNQDLGIGLVNRLITFGTQSISIRTPFTCRSTSWICRLCYGRSPTHGDLVELGEAVGIIAGQSIGEPGTQLTLRTFHTGGVFTGGTAEHVRAPYNGKIKFNEDLVHPTRTRHGHPAFLCYIDLSVIIESEDIIHSVTIPPKSFLLVQNDQYVESEQVIAEIREGTYTFHFKERVRKYIYSDSEGEMHWSTDVSHAPEFTYSNVHLLPKTSHLWILSGGSCGSSLIRFSIHKDQDQMNIPFLSAERKSISSLSVNNDQVSQKFFSSDFADPKKLGIYDYSELNGNLGTSHYNLIYSAIFHENSDLLAKRRRNRFLIPFQSIQEQEKEFIPQSGISVEIPINGIFRRNSIFAFFDDPRYRRKSSGILKYGTLKADSIIQKEDMIEYRGVQKIKTKYEMKVDRFFFIPEEVHILPESSAIMVQNYSIIGVDTRLTLNIRSQVGGLIRVEKKKKRIELKIFSGDIHFPDKTDKISRHSGILIPPGRGKKNSKESKKFKNWIYVQRITPTKKKFFVLVRPVATYEIADSINLATLFPQDLFREKDNIQLRVFNYILYGNGKPTRGISDTSIQLVRTCLVLNWDKNSSLEEVRAFFVEVSTKGLIQDFIRIGLVKSHISYIRKRNNSPDSGLISADHMNPFYSISPKSGILQQSLRQNHGTIRMFLNRNKESQSLLILSSSNCFRMGPFNHVKHHNVINQSIKKNTLITIKNSSGPLGTATPISNFYSFLPLLTYNQISLIKYFQLDNLKYIFQKINSYLIDENGIILNLDPYSNVVLNPFKLNWYFLHQNYHHNYCEETSTIISLGQFFCENVCIAKKEPHLKSGQVLIVQRDSAVIRSAKPYLATPGAKVHGHYSEILYEGDTLVTFIYEKSRSGDITQGLPKVEQVLEVRSIDSISLNLEKRIKGWNKCITRILGIPWGFLIGAELTIVQSRISLVNKIQKVYRSQGVQIHNRHIEIIVRQITSKVLVSEEGMSNVFLPGELIGLLRAERTGRALEEAICYRAVLLGITRASLNTQSFISEASFQETARVLAKAALRGRIDWLKGLKENVVLGGVIPAGTGFNKGLVHCSRQHTNIILEKKTKNLALFEGDMRDILFYHREFCDSSISKSDFSRI
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta'', PEP, Plastid-encoded RNA polymerase subunit beta'', RNA polymerase subunit beta''.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NUOB_BRUME
Sequence: MGLTGTNTTLVAPQPKGILDPRTGKPVGSDDAFFNDLNGELSDKGFIVTSADALITWARTGSLMWMTFGLACCAVEMMHISMPRYDAERFGIAPRASPRQSDVMIVAGTLTNKMAPALRKVYDQMPEPRYVISMGSCANGGGYYHYSYSVVRGCDRVVPVDIYVPGCPPTAEALLYGILLLQKKIRRTGTIER
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CAV1_PLEMO
Sequence: MSGGKYVDSEGHLYTVPIREQGNIYKPNNKAMADELSEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYIHTVCDPLFEAIGKIFSNVRISLQKEI
What is the function of this protein?
May act as a scaffolding protein within caveolar membranes.  Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation.  Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity).  Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity).  Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation.  Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner (By similarity).  Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway (By similarity).  Negatively regulates TGFB1-mediated activation of SMAD2/3 by mediating the internalization of TGFBR1 from membrane rafts leading to its subsequent degradation (By similarity).
What are the official names of this protein?
Caveolin-1.
What is the protein family that this protein belongs to?
Belongs to the caveolin family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Membrane raft. Note=Colocalized with DPP4 in membrane rafts. Potential hairpin-like structure in the membrane. Membrane protein of caveolae (By similarity).
Protein: GTR12_BOVIN
Sequence: MVPVENAEGPSLLKPKGRAAETDGSDRASGGPHPPWARGCGMYTLLSSVTAAVSGFLVGYELGIISGALLQIRTLLVLTCHEQEMVVSSLLIGALLASLIGGVLIDRYGRRAAIILSSCLLGLGSLVLIISLSYTTLIGGRIAIGVFISLSSTATCVYIAEIAPQHRRGLLVSLNELMIVIGILFAYISNYAFANISHGWKYMFGLVIPLGVLQAIAMYFLPPSPRFLVMKGHEEAASKVLGKLRAVLDTTEELTVIKSSLKDEYQYSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGFQSNEAASLASTGVGVVKVISTIPATLLVDQVGSKTFLCIGSSVMAASLVTMGIVNLNIHMNFTSICRNHSPINQSLDESVFYGPGNLSASNDTLRESFKGMTFHSRSSLRPTRNDINGRGETTLASLPNAGLSQTEYQIVTDSADVPTFLKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFLTVTDLIGLPWVCFIYTVMSLASLVFVIVFIPETKGCSLEQISVELAKENYVKNNICFMSHHREELVPKQLQKRKPQEQFLESKKLRGKGQPRQLSSEV
What is the function of this protein?
Insulin-independent facilitative glucose transporter.
What are the official names of this protein?
Solute carrier family 2, facilitated glucose transporter member 12, Glucose transporter type 12, GLUT-12.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endomembrane system; Multi-pass membrane protein. Cytoplasm, perinuclear region. Note=Localizes primarily perinuclear region in the absence of insulin.
Protein: S45A2_HUMAN
Sequence: MGSNSGQAGRHIYKSLADDGPFDSVEPPKRPTSRLIMHSMAMFGREFCYAVEAAYVTPVLLSVGLPSSLYSIVWFLSPILGFLLQPVVGSASDHCRSRWGRRRPYILTLGVMMLVGMALYLNGATVVAALIANPRRKLVWAISVTMIGVVLFDFAADFIDGPIKAYLFDVCSHQDKEKGLHYHALFTGFGGALGYLLGAIDWAHLELGRLLGTEFQVMFFFSALVLTLCFTVHLCSISEAPLTEVAKGIPPQQTPQDPPLSSDGMYEYGSIEKVKNGYVNPELAMQGAKNKNHAEQTRRAMTLKSLLRALVNMPPHYRYLCISHLIGWTAFLSNMLFFTDFMGQIVYRGDPYSAHNSTEFLIYERGVEVGCWGLCINSVFSSLYSYFQKVLVSYIGLKGLYFTGYLLFGLGTGFIGLFPNVYSTLVLCSLFGVMSSTLYTVPFNLITEYHREEEKERQQAPGGDPDNSVRGKGMDCATLTCMVQLAQILVGGGLGFLVNTAGTVVVVVITASAVALIGCCFVALFVRYVD
What is the function of this protein?
Proton-associated glucose and sucrose transporter (By similarity).  May be able to transport also fructose (By similarity).  Expressed at a late melanosome maturation stage where functions as proton/glucose exporter which increase lumenal pH by decreasing glycolysis (PubMed:32966160, PubMed:35469906).  Regulates melanogenesis by maintaining melanosome neutralization that is initially initiated by transient OCA2 and required for a proper function of the tyrosinase TYR (PubMed:32966160, PubMed:35469906).
What are the official names of this protein?
Membrane-associated transporter protein, Melanoma antigen AIM1, Protein AIM-1, Solute carrier family 45 member 2.
What is the protein family that this protein belongs to?
Belongs to the glycoside-pentoside-hexuronide (GPH) cation symporter transporter (TC 2.A.2) family.
Protein: EX7S_STAHJ
Sequence: MSKDQQSFEEMMQELENIVQKLDNETVSLEESLELYQRGMKLSATCDATLKDAEKKVNQLIKDEAEDEENGKEVNE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERLEC_XENTR
Sequence: MRRSDRLRCAGASLLVVLCGVFRSSFGGRTLPALSDDIPFRLKWPGPDFTLPTAGIPYKEDNYIIMTTADKEKYKCLLPLMANGNEEQDGEYKGPSPGALLEPLFKLSSCSYRIESYWTYEVCHGKYIRQYHEEKETGQKLSIQEYYLGKMMKKSTTEAGENQEEKESAESPKEIYTKNIEGQMTPYYPVEMINGTPCSLKQNQPRSSTVMYICHPESKHEILSVAEVTTCEYEVVILTPLLCNHPKYRFRTSPINDIFCQSMPGSPLRPQSLVKLEHQKEEIKSPLKPNKEEEQQLLREKFSTIHKPVTVGSQQQVTVGTTHISRLTDEQLIKEFLSGSYCFHGGVGWWKYEFCYGKYVHQYHEDKDTGKTTVVVGTWKADEHQEWAKKNLARAYMTTPDGVQTVKTVSHFYGGGDVCEVSEQPRQVIVKLKCKESESPHAVTVYMLEPQTCQYILGVESPVICKILDTADENGLLSIPN
What is the function of this protein?
Probable lectin that binds selectively to improperly folded lumenal proteins.  May function in endoplasmic reticulum quality control and endoplasmic reticulum-associated degradation (ERAD) of both non-glycosylated proteins and glycoproteins (By similarity).
What are the official names of this protein?
Endoplasmic reticulum lectin 1, ER lectin, Erlectin.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: CGR1_CHAGB
Sequence: MSTTIVDGAQAPESAVTKPLGMRKNGKQWHAPKKAFRPGSGLTSYEQRAKTRVAQAATKAKEKELKEEKEAERKRRMQALVEKRAAKAEKERYELLAAKMHKKRLERLKRKEKRNKVLNS
What is the function of this protein?
Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit.
What are the official names of this protein?
rRNA-processing protein CGR1.
What is the protein family that this protein belongs to?
Belongs to the CGR1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: HBB_LAMGL
Sequence: MVNLSGDEKNAVHGLWSKVKVDEVGGEALGRLLVVYPWTRRFFESFGDLSTADAVMNNPKVKAHGSKVLNSFGDGLSHLDNLKGTYAKLSELHCDKLHVDPENFRLLGNVLVVVLARHFGKEFTPDLQAAYQKVVAGVANALAHRYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: WDY_DROME
Sequence: MSVIFNASVNTKSAVEYQTISSTQSHSAEEQSERLHKWISKDQLEKLYSSFLNTPERHVGIDELRIILEELDITFNDSMYTRLFLKINQNRDFKVDWNEFVSYLIFGFQEEDPSSQKESLILPISGPPMVRKSEHRSAICCLALLKAKSDQVPIDEVTETINFSFGGEDSPEASGMWVTASHEGMMRFWTSHMEPIRTASSESICMSYAFFNNGKVHSKLILGDYAGNVRVLSYSPHLRGPFQAKPGAALIEVVWSDILRGKIPQFFPKEYINLHNEMVSCVYFSLHMNALFASAEYRNTKKYRGRCPGMIMVTYDERSNFRIPLGVSTFFVAESHNIVVTGGPDTFVRIWDVYIPTEPSAILTGHNGGIVLVFVQPEENKVYSVDYQKIIKVWDLHEHTLLQTYGDLVRLIHHSETDLTYYYHSHLRELVVAGRKLISIKCCPRVRVDLTDGNTHAAPVSVVLYNRLFRNIVSCGLDSYIIVWDPWTGRRKIIMKSCHTKMIYGEIIDIEITAACFDPLEQFLLTGARDGSLKIWNYNNAVVVRNMSIMPDQEVTAVIWVVDRILAMGWDRQVTEFNDVVGREYGDPKKWPKFHTDDITCADVKLGEGVVTATYSGEIIFWKLETGQPYRRYSVMDPTRFIELKLTAEEEKFIRQSKRLASRLTHSGNHSLQTGRAGRSTVLNRPEDNRDYGTDIPISVQAVLFLQTRPQTLKHGSVFISLDTGFIQVYSHHQRGGYIVEFLAVHKTGDCVLTMCTDRKNRYLYTGTAFGYIKVWYIVNFCVPESEKTHVCMPKLRLEFIFLRKELFMTRAKRAVRNQAEPLLVSSYKGHLKAINSIAFINLPKIIFTGSHDYSCRLWTQGGRYLGTLGTVLPWSRLTPFERAGDDNHLYRMPPDIKKVASSTTLKVISGIQAETSIKISNGKTVEDREEETAQTEDVTELRKLLDKPVKEPIVGKHFELPGRSILDQHIELDTTQSYIAVFTQLKVHSTEMLERLPTPAVVSRVQTENYMDHYIPVEGKVDVSGSAINIKQPSRRRSDKASDTRNVNTLGARDHVPLDFSSSHASQS
What are the official names of this protein?
WD repeat-containing protein on Y chromosome, WD40 Y.
Protein: SSRP_CLOBL
Sequence: MSKKKGSNTLAENRKARHDYFIEETYEAGIELVGTEVKSIRQGKANLKDSYAEIRNGEVFVRNMHISPYEQGNIYNKDPLRDRKLLLHKSEIYKLVGFTTQQGYTLIPLSLYLKHGRVKVSLAVAKGKKNYDKRDAMLEKAAKREMDRQIKERSRY
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: YIDD_HELPJ
Sequence: MRNNKTPFLSAIFTASIRGYQRFFSAFTFSSCRFYPTCSNYALWLLCFESPLVAMGKIAIRILSCNPFCSGGIAYPTTRLKRPSLLQSHKDFNRNFKTITFWLVPTTKSRATYYIIKV
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RK20_LATCL
Sequence: MTRIKRGYIARRRRTKMRLFASSFRGAHSRLTRTITQQKIRALFSAHRDRDKQKINFRRLWIARINAVIRKRGVSYSYSKLIHDLYKRQLLLNRKILAQIAISNRNCLYMISNEIIKETERKEYTGII
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit (By similarity).
What are the official names of this protein?
50S ribosomal protein L20, plastid.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
What are the subcellular locations of this protein?
Plastid.
Protein: MIAA_SACD2
Sequence: MAESNKELVDRLSAPRGDRKPLAIALVGPTAAGKTDLAIALHQQLGAEIISVDSAMVYRDMNIGTAKPTASELALAPHRLIDIRDPAEAYSVADFCRDAKAEIESIHSQGKIPVLAGGTMMYFKALLEGLSDMPASDPAVRAQIDKRASEEGWPALHSELASVDPETAANIHPNHSHRISRALEVYVISGKRMSAWRGQANNGLIDTYDWVQICVAPRERTLLHQRIAQRFDMMLEQGFIDEVRALYSRNDLNVDMPSIRAVGYRQAWDYLAGVSSYDEMREKGIAATRQLAKRQFTWLRSWQGLEWIYTQDEDANLLSSEEIVNKALNYLAKRTI
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.