PharMolix/UniProtQA huggingface dataset:
Protein: EMC1_SCHPO
Sequence: MLRPLWPLFLTALFLNIYRAASVLIDEAGKNDFEISLLGKVNDLVYDTKNEYLYAVSQKGLLAKLNASNGDVIWRQSIAPETSQLNYNPVTNFIITVDKDYLYIWNSKNGILDRKIELADGKGKLFEVNKGFVYLNPHTRKFIELDLQASFSISIERDLQLDAISFLTYAEKNYVLFKRDGQFVLQALDHNYAVYGPETVLNVPENAQLLVTEKDVIIYSSNGVIYGIHVSMADISQLLIDEYKTFEWSSIPGKRHGYSITVDSQSTPVTYLFVIIDSEFVLIDEYIHEDTEALGYIHMEDNQTFSRVFAVANQIKFAPATVITIPNQLSRPVFRLFTFAEGEISAIVILDDGTFFSFSNTELVWKREEALAYAINPSILPTTLLTSYQKSIQDEENSSVSFLNRWYRHFNQLIDFLKHPHGFTSSSVLDDAFTTKIIIPTSTGSIFCLSSDPKQVHRILWRYDFNINPESVESWLLDISDEDPKFAFVHQWNDAFSFYILNASDGSVISQKSRDFKADEFYYVDNISKNLPNQIFAVKDYKVLPLTGDNSIFEKISQEANSIFVYTSETKVEGFSISADLTMDVQWSYNLAEGEIVIASIRRNPHEIVASFGRVLQNREVMYKYLNPNLFALFSKCKNDLVVYVMDSVTGSIVYQNKHQGIILFDKVYGVFSENWLVYSYQSDVPNLSTKIISVELFEGSHSNEKIDSNEIYSRHNDYRPYAFTKAYIFDREITTLGVTNTPQGITSRDVLLGLSSNQVAMIPQALLSPMRPVLRPNEKANDASFIPYEPIIPLNDDMVLSYNKRVYGVSQITSGITNFESTTLVLSTGLDVFFTRTAPSMPYDMLSSHFDKKQLMLTTFGILLAVLLTKPLVKKKQLNTKWYN
What is the function of this protein?
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.  Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues.  Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices (By similarity).  It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes.  By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins (By similarity).
What are the official names of this protein?
ER membrane protein complex subunit 1.
What is the protein family that this protein belongs to?
Belongs to the EMC1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: MIAA_BACC4
Sequence: MGEVQREKVAVIIGPTAVGKTKLSIDLAKALNGEIISGDSMQIYRTMDIGTAKVTKAEMDGIPHYMIDIKNPEDSFSVAEFQERVRKHIREITERGKLPIIVGGTGLYIQSVLFDYQFTDDAGDVIYREQMEKLALERGVEYVHKKLQEVDPESAERIHANNVRRVIRALEIFHMTGEKMSDQIEKQEKELLYDVSLIGLTMDREMLYDRINLRVDLMMEQGLLEEVEGLYNRGIRDCQSIQAIGYKEIYDYFENRASLEDAVSQLKTNSRRYAKRQLTWFRNKMDVTWFDVTDGEKTSEILRYIEGKLQVKSNNSK
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: RS11_XYLFA
Sequence: MAKQSVVKIKKKVKRVITDGVAHISASFNNTIVTITDRQGNSLFWCTSGASGFRGSRKCTPFAAQVAAEKAGRAVLDYGMKSLEVRINGPGPGRESAVRSLNNVGYKITNIIDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: DUT_SALTI
Sequence: MKKIDVKILDPRVGQQFPLPTYATSGSAGLDLRACLDDAVELAPGATTLVPTGLAIHIADPSLAAVMLPRSGLGHKHGIVLGNLVGLIDSDYQGQLMVSIWNRGQDSFTIEPGERIAQMVFVPVVQAEFNLVEAFDATERGEGGFGHSGRK
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: Y2777_ACIET
Sequence: MPLKDLPLDAQPREKLLARGPAALSDAELLAILLRTGLAGKGVLQLAQELLDDPVRDPATGRSAGGGFGGIAGLLHASSQDLQRIKGLGPAKRAELMAVLELARRAMAQQLREREVFDSPQAVQHYLQLHLAGRTHEVFAVLFLDSGNRLIAMEELFRGTLTQTSVYPREVVLRALHHHAAAVVLAHNHPSGSVQPSRADEALTQTLKAALALVDVRVLDHVIVAPGAALSMAEQGLV
What are the official names of this protein?
UPF0758 protein Dtpsy_2777.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: TRPB_FRAT1
Sequence: MSKLNAYFGEYGGQFVPQILVPALDQLEQEFIKAQADESFKQEFKELLQEYAGRPTALTKTRNIVKNTRTKLYLKREDLLHGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVATALACALLDLKCRVYMGAKDVERQSPNVFRMKLMGAEVIPVHSGSATLKDACNEALRDWSANYSKAHYLLGTAAGPHPFPTIVREFQRMIGEETKQQMLAKEGRLPDAVIACVGGGSNAIGMFADFIDEKNVKLIGVEPAGKGIETGEHGAPLKHGKTGIFFGMKAPLMQNSDGQIEESYSISAGLDFPSVGPQHAHLLAIGRAKYASATDDEALDAFKLLCKKEGIIPALESSHALAHALKLAYEDPNKEQLLVVNLSGRGDKDIFTVHDILKEKGEI
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: MAD4_MOUSE
Sequence: MELNSLLLLLEAAEYLERRDREAEHGYASMLPFDGDFARKKTKTAGLVRKGPNNRSSHNELEKHRRAKLRLYLEQLKQLGPLGPDSTRHTTLSLLKRAKMHIKKLEEQDRRALSIKEQLQREHRFLKRRLEQLSVQSVERVRTDSTGSAVSTDDSEQEVDIEGMEFGPGELDSAGSSSDADDHYSLQSSGCSDSSYGHPCRRPGCPGLS
What is the function of this protein?
Transcriptional repressor.  Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'.  Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation.
What are the official names of this protein?
Max dimerization protein 4, Max dimerizer 4, Max-associated protein 4, Max-interacting transcriptional repressor MAD4.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y3629_VIBA3
Sequence: MELKVDTHTHTYASGHAYSTLIENAKSAKQNGLAMFCTTDHSESMPGAPHYWFFSNQRVLPRFIEDVAIIRGVESNIMNTQGEIDIHPSVDKNLDWVIASFHEPVFRPSDVATHTEALLNVIKGGRVDALGHLGNPNFDFDFEVVIQCAAEHNVAIEINNTTLKGNSRVGSVDRCYEIARIAKAKGAFITTGSDAHFCIDVGGLDLVSSLLGEVGVDSSKVITHSPQQFLAFLVLRGRQSIAEFSVFE
What are the official names of this protein?
Probable phosphatase VS_II0429.
What is the protein family that this protein belongs to?
Belongs to the PHP family.
Protein: Y747_TREPA
Sequence: MVSASSFYVPAAVKKNFNALVRHVKGVLSVLDECDPKNNVADQVNLLLCAKEMQSEQVAALLSVLLIDTWGYRLFSYNLRKVSVEGLGFAQETARWKGVDIVLGYHHPDLGFLAINPKNPSNASLVEGFRKNELLLVYVGKQDRGPLDERIADEVAKGLIALIENRKFVVPKEILSGVFAFVSTKKSEGSGKRVRSAKKSGADAARASEGATCDRASSESVSPTARPPAQASAGPIRMSQLISVPVSNELFHNGNVEAWKRIIRSYNARYPSSEVIVFYDGERIVDINTLFKWGKVKHGSVIQFAVSGEEIKDLSKLSKYFKEGASSRFEVFLHGSPDTVLNLF
What are the official names of this protein?
Uncharacterized protein TP_0747.
Protein: IRC19_YEAS2
Sequence: MRKPSITITTAKAIITPDYTLIKSHSKYQLPSRFQKLDADSPERSTVVKLFYRRFMRLKPFISNVKMVKDTYRDYVRYKFMKENYELKRYLVFNPDGLRSKIKLELLSNTKCCERILPVTEMQRTLEFVLKSCSYLPETKVQKWDIARDNTYCRQILKNLLTMQYEKYRSILHRGIGHDELDVKFSHLKTTSSPLTKLNKTEKKKIPLFKVFSDFDTTLIYLNETLGTRL
What is the function of this protein?
Involved in sporulation and maintenance of the mitochondrial DNA.  Is probably involved in a pathway contributing to genomic integrity (By similarity).
What are the official names of this protein?
Increased recombination centers protein 19.
What is the protein family that this protein belongs to?
Belongs to the IRC19 family.
Protein: RS7_LACLM
Sequence: MRKNRAPKREVLADPMYNSIVVTRLINRVMLDGKRGVAAQIVYGAFKQIEEATGNNPLEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLRWLVTIARNRGEHTMQDRLAKEILDAANNTGAAVKKREDTHKMAEANRAFAHFRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: KHSE_BRUC2
Sequence: MAVYTDINEIELGAFLRHYDIGTLTSYKGIAEGVENSNYLLHTSSGSFILTLYEKRTNREDLPFFLGLMQHLAKRGLECPQPVVRNDGAMIGQLAGRPAAIVTFLEGMWMRRPTVAHCEAVGEGLAHMHLAGADFPMRRRNGLTLPDWRPLWNLSRKCADTVERGLVAETEADLDFLEKNWPADLPQGVIHADLFPDNAFFLGDRLSGFIDFYFACTDILAYDVAVCLNAWCFEKDFSYNRTKGAALLRGYTSVRPLSEAEADALPVLARGAAVRFMLTRLYDWLTVPAGSFVVKKDPMEYVRRMRFHRQIESAAEYGLEMQGVAA
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the pseudomonas-type ThrB family.
Protein: BTBDI_MOUSE
Sequence: MCSPASSKILYRNPRFLRVAFLQLHHQQQSGVFCDALLQAEGEAVPAHCCILSACSPFFTERLERERPVQGRKVVLEMGGLKIQTLRKLVDFLYTSEMEVSQEEAQDVLSAARQLRVSELETLQLEGGKLVKAPQGRRLNRECLQPPAAAPISARVVGPKSRPQTPLPVTQTPSPLGAVRLKSLGEEEGAHKKTNLPNADSLSDTQLKKKARVCLTQESRSSPSSQREGPKETKSNPGPTALPSLYPSVDEQLLPRKIRLSRSKPSPHVYTSTPSSILSGPSSMPTAPGRRLWRQRTVSKEAQGVDKQKPGEVRPLQSTPDPSDVGKPAENKKQSPELRAPTSSSVEEGQVGRVKLRKIVNGTCWEVVQEPPLRNTQDSPQILEPSDVEEPSGTLLSSVNEQEIPARIQLCQDSPESPRLQDILLSASHSPDHPMVKSEFGSSPMLTGKESDLNIDCREPYTFDTTLLGQPCEAEQYRITSAAATSELEEIFDFMLCGSDVEPPVGSLESPGAEGCRTPSYHLSETGKNWIEGEEWCLPDMELWPRDLTGLEKEPVSENKEPVEPFSPLVMRSENTESFEPLSPLVMPSEVSREELSLRGSWTPDLEITSSQPLDGQGEKLLHFDSSDPSQRSYNHLSPPCSDWAETGLEVSLGMDDVLCPVPKAVREVSANPEQLDPLPGSSEDEEIDVVDWTVEKKLGPTSVPSVWPDPSSESETEVDILT
What is the function of this protein?
Specifically required during spermatogenesis to promote expression of piRNA precursors.  The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons, which is essential for the germline integrity.  Acts by facilitating transcription elongation at piRNA loci during pachytene.
What are the official names of this protein?
BTB/POZ domain-containing protein 18.
What are the subcellular locations of this protein?
Nucleus.
Protein: MORC7_ARATH
Sequence: MDNSIHVKREIQLPSTSPAGFPGRESVTVVDLCSSDDDSDIGEVAGGLEKVGNNFVGLKRGRDTFGGSSEVDRNNVKKVTTLAELGVGLPEGFGQSNPPESLTHPIPANPCNVFRPVPPPPPPPYAGTSGKIGGCKQFWKAGDYEGAAGDNWDLSSGGFDHVRVHPKFLHSNATSHKWALGAFAELLDNALDEVASGATYVKVDMLENNKGGNRMLLIEDNGGGMDPEKMRQCMSLGYSAKSKLANTIGQYGNGFKTSTMRLGADVIVFSRCPGKDGKSSTQSIGLLSYTFLRSTGKEDIVVPMLDYERRDPEWSKIIRSSTRDWDKNVETIIQWSPFSSEEDLLHQFDLMKDRGTRIIIYNLWEDDQGMLELDFDADPYDIQLRGVNREERNIKMASQFPNSRHFLTYKHSLRSYVSILYLRIPPGFRIILRGIDVEHHSVVNDMMQTEQITYRPQSESYGVVTNMSAIVIIGFVKDAKHHVDVQGFNVYHKNRLIKPFWRIWNATGSDGRGVIGVLEANFVEPAHDKQGFERTTVLARLESRLVQMQKTYWSTNCHKIGYAPRRREKSAYGYDNRDSSPENDREGPSSIKTPTPASDKFYSSSYPNHNGDNGVSGKDGARLQEELRREKERRKALEVEVQLSRQKIEEMKKEQENLIEIFSEERDRRDGEEEVLRNKLEEASNTIDDLLNKIKKMEGSKVPSWRH
What is the function of this protein?
Exhibits ATPase activity.  Binds DNA/RNA in a non-specific manner and exhibits endonuclease activity.  Probably involved in DNA repair.  Involved in RNA-directed DNA methylation (RdDM) as a component of the RdDM machinery and required for gene silencing.  May also be involved in the regulation of chromatin architecture to maintain gene silencing.  Together with MORC4, acts to suppress a wide set of non-methylated protein-coding genes, especially involved in pathogen response.  Positive regulators of defense against the oomycete Hyaloperonospora arabidopsidis (Hpa) (PubMed:27171361).
What are the official names of this protein?
Protein MICRORCHIDIA 7, AtMORC7, Protein CRT1-homolog 3, CRT1-h3.
What is the protein family that this protein belongs to?
Belongs to the MORC ATPase protein family.
What are the subcellular locations of this protein?
Nucleus. Note=Accumulates in discrete nuclear bodies adjacent to chromocenters.
Protein: PYRE_PSEA7
Sequence: MQAYQRDFIRFAIERGVLRFGEFTLKSGRTSPYFFNAGLFDSGLALARLGRFYAEAVIDSGIDFDVLFGPAYKGIPLAATTAVALAEQHRRDLPWCFNRKEAKDHGEGGTLVGAPLSGRVLIIDDVITAGTAIREVMQIIDAQGARAAGVLIALNRQERGKGELSAIQEVERDFGMPVVSIVSLEQVLEYLAGDAELKKHLPAVEAYRAQYGI
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: AGUA_EMENI
Sequence: MRSFLLLTALLGVAAVAEDGLAAWLRYAPIPHAKSYHKNLPSVIVPLNATAGRPIDTAAYELVDGIKGIFGKRVTLKNETRDDPNLPAVTVGTVEAYAEAGGDVSSVPELIDDGYYLSVAGPSVLILGQNERGALYGTFQYLERLAQGKVSDTSFASNPSAPIRWVNQWDNLQDGGTHGSVERGYGGDSIFFWDGRVRDDLTRASQYARLLASIGLNAVIVNNVNANETILTQENMDGVARIADAFRPYGIQLGLSLNFASPQSLGGLDTFDPFDERVISWWGEITDELYERIPDMAGYLVKANSEGQPGPFTYNRTLADGANLFARALQPHGGIVLFRAFVYDHENLNETLDWKADRANAAVEFFDGLDPQFEDNVVIQIKNGPIDFQVREPVSPLFAHLSQTASAVELQVTQEYLGQQCHLVYLAPMWKEVLDFDLRVDGKDSVVSDIVSGRRFNNTLGGYAGVVNVGLNTTWLGSHLAMSNLYAYGRLAWDPSADSVELLQEWIKMTFSHDQEVVDVITKMSMESWPAYENYSGNLGIQTLTDILLGHYGPNPASQDGNPWGQWTRADADSIGMDRTVWNGTGNAGQYPEEVYQMYENIDTTPDNLLLWFHHVPYTQRLKSGKTVIQHFYDAHYRGSATAQTFVSLWKTIKGKIDKERYEHVLFRLVYQAGHALVWRDSITNFYYNKSGIPDEAGRVGNHPYRIEAEDMELDGYEPYLVSPFEAASGSHCIVTSNNSTEGRASTPLKVKNGKYDIAVNYFDQAIGNSTWRLFLDDDLVGEWKGDLEYILGRAPSPYIDGQTAARITFKHVHIKSRSTLSIVGIPDGMEPAPIDYVSILPEGVID
What is the function of this protein?
Alpha-glucuronidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.  Releases 4-O-methylglucuronic acid from xylan.
What are the official names of this protein?
Alpha-glucuronidase A, Alpha-glucosiduronase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 67 family.
What are the subcellular locations of this protein?
Secreted.
Protein: AQP_HAEIX
Sequence: MVEKLDMSAVVGVKDITDNKKIWRQLMAELIGTFFLVVIGVGSCTGGSEWSPSIPQIAFTFGLTVATLAQAIGHISGCHINPAVTVGFLIVGEMSIIKSVLYIAVQCVGAIAGAAVIKVGVSEAVSGLDLGVSSFSSTLTVGQAVLIEALITFILVVVVKGVSDPGRTDIKGSAPLAVGLSIAAGHLCAIKLTGASMNPARSFGPAVVQNMWIDHWVYWVGPIVGAIVAALLYKFVFKVRKGDDEANSYDF
What is the function of this protein?
Forms a water-specific channel.
What are the official names of this protein?
Aquaporin, BfWC1, Water channel 1.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CYB_SYRRE
Sequence: MAPNIRKSHPLLKIINNSLIDLPAPSNISAWWNFGSLLAVCLTTQILTGLLLAMHYTADTSLAFSSVAHTCRNVQYGWLIRNLHANGASFFFICIFLHIGRGLYYGSYLYKETWNTGVILLLTLMATAFVGYVLPWGQMSFWGATVITNLFSAIPYIGQTLVEWAWGGFSVDNPTLTRFFALHFLLPFVITGITITHLMFLHESGSNNPLGISSNSDKIPFHPYYSLKDILGLALMLTPFLTLALFSPNLLGDPENFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASVLILLLIPFLHKSKQRTMTFRPLSQALFWLLVANLLILTWVGSQPVEHPFIIIGQMASLSYFTILLILFPAIGTLENKMLNY
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y3143_MYCTU
Sequence: MPDSSTALRILVYSDNVQTRERVMRALGKRLHPDLPDLTYVEVATGPMVIRQMDRGGIDLAILDGEATPTGGMGIAKQLKDELASCPPILVLTGRPDDTWLASWSRAEAAVPHPVDPIVLGRTVLSLLRAPAH
What are the official names of this protein?
Uncharacterized response regulatory protein Rv3143.
Protein: NPD_LEPIN
Sequence: MKEFITKHRDKFQKISAISGAGISAESGIPTFRGSEGLWKNFRAEDLATPQAFSKNPKLVWEWYLWRRNIIETKRPNPGHFALVELERIHPDFFLITQNVDGLHSQAGSKKLTEIHGNIFINRCISCGQESKETISENTTPLPPQCQNCNSFLRPGVVWFGESYDDFKLNLSIQRMKHTDLLLVLGTSGSVSMPVYLAQIAKDSGALLIEINPERSSFSSSVDLFLQGKTGEVLPELIREILDNPS
What is the function of this protein?
NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins.  Modulates the activities of several proteins which are inactive in their acylated form.
What are the official names of this protein?
NAD-dependent protein deacylase, Regulatory protein SIR2 homolog.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class III subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PP429_ARATH
Sequence: MALNSSAFFVPCHNYNQICDLLLSSARTRSTIKGLQLHGYVVKSGLSLIPLVANNLINFYSKSQLPFDSRRAFEDSPQKSSTTWSSIISCFAQNELPWMSLEFLKKMMAGNLRPDDHVLPSATKSCAILSRCDIGRSVHCLSMKTGYDADVFVGSSLVDMYAKCGEIVYARKMFDEMPQRNVVTWSGMMYGYAQMGENEEALWLFKEALFENLAVNDYSFSSVISVCANSTLLELGRQIHGLSIKSSFDSSSFVGSSLVSLYSKCGVPEGAYQVFNEVPVKNLGIWNAMLKAYAQHSHTQKVIELFKRMKLSGMKPNFITFLNVLNACSHAGLVDEGRYYFDQMKESRIEPTDKHYASLVDMLGRAGRLQEALEVITNMPIDPTESVWGALLTSCTVHKNTELAAFAADKVFELGPVSSGMHISLSNAYAADGRFEDAAKARKLLRDRGEKKETGLSWVEERNKVHTFAAGERRHEKSKEIYEKLAELGEEMEKAGYIADTSYVLREVDGDEKNQTIRYHSERLAIAFGLITFPADRPIRVMKNLRVCGDCHNAIKFMSVCTRRVIIVRDNNRFHRFEDGKCSCNDYW
What are the official names of this protein?
Putative pentatricopeptide repeat-containing protein At5g52630.
What is the protein family that this protein belongs to?
Belongs to the PPR family. PCMP-H subfamily.
Protein: RL31B_STRP8
Sequence: MRKDIHPDYRPVVFLDTTTGYQFLSGSTKASKETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAK
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: END4_BACCZ
Sequence: MLKIGSHVSMSGKKMLLAASEEAVSYGATTFMIYTGAPQNTRRKPIEELNIEAGRKHMEQNGIEEIIVHAPYIINVGNTTKPETFQLGVDFLRMEIERTSALGVAKQIVLHPGAHVGAGADAGIQQIIKGLNEVLTPDQTVNIALETMAGKGTECGRSFEEIAKIIDGVKYNEKLSVCFDTCHTHDAGYDIVNDFDGVLNEFDKIVGIDRLQVLHINDSKNVRGAGKDRHENIGFGHIGYKALHHIVHHPQLTHVPKILETPYVGEDKKDKKPPYKLEIEMLKNGTFDEGLLEKIKAQ
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: TRPD_PSEAB
Sequence: MDIKGALNRIVNQLDLTTEEMQAVMRQIMTGQCTDAQIGAFLMGMRMKSETIDEIVGAVAVMRELADGVQLPTLKHVVDVVGTGGDGANIFNVSSAASFVVAAAGGKVAKHGNRAVSGKSGSADLLEAAGIYLELTSEQVARCIDTVGVGFMFAQVHHKAMKYAAGPRRELGLRTLFNMLGPLTNPAGVRHQVVGVFTQELCKPLAEVLKRLGSEHVLVVHSRDGLDEFSLAAATHIAELKDGEVREYEVRPEDFGIKSQTLMGLEVDSPQASLELIRDALGRRKTEAGQKAAELIVMNAGPALYAADLATSLHEGIQLAHDALHTGLAREKMDELVAFTAVYREENAQ
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: SEM1_SCHPO
Sequence: MSRAALPSLENLEDDDEFEDFATENWPMKDTELDTGDDTLWENNWDDEDIGDDDFSVQLQAELKKKGVAAN
What is the function of this protein?
Versatile protein that might stabilize multiple protein complexes involved in diverse pathways.  Subunit of the 26S proteasome which plays a role in ubiquitin-dependent proteolysis (PubMed:16149916).  Acts as a ubiquitin receptor of the 26S proteasome, by interacting with ubiquitin chains linked by 'Lys-63' and 'Lys-48' (PubMed:25306921).  Involved in nuclear export of specific sets of mRNAs (PubMed:18023413).  Links the mRNA adapter mlo3 to rae1 for targeting mRNA-protein complex to the proteins of the nucleoporin complex (NPC) (PubMed:15990877).  Involved in recombinational repair of DNA.  Plays a critical role in linking repair and checkpoint factors to damaged DNA sites by specifically recruiting rad24 and cdc25 to the DSBs (PubMed:20231270).
What are the official names of this protein?
26S proteasome complex subunit rpn15, mRNA export factor dss1.
What is the protein family that this protein belongs to?
Belongs to the DSS1/SEM1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: YG5K_YEAST
Sequence: MTYLRIALASNKRKGSFVLRNSMAALSLSTSGFKFLLAYSSARAIFKLFANCKWAGCFFDLSKEMRKDMLVVNFRFFFKFYSSTKMHIRKQIIINIRHRRKFVIVFFFFSFSLSISCVQKFFLPPKSFVPRDIEKK
What are the official names of this protein?
Putative uncharacterized protein YGR265W.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ADE_SPHAL
Sequence: MPDGFASHEERAAFIAGLPKAELHLHIEGSLEPELLFEFARRNRVAIPFASIDDVRAAYAFTNLQDFLDIYYQGMGVLHTEQDFFDLTAAYCARANADSVRHIEIFFDPQGHTARGVAFETVITGITRALDDAEARYGITSKLILCFLRHLSEAEAEATLDEALPFLGRIAGVGLDSSEVGHPPAKFERVFARARSLGLKTVAHAGEEGPPEYVREALDLLKVDRIDHGNRSLEDPALVARLAASDMTLTVCPLSNLKLCVVDDIADHPLKIMLDADLKATVNSDDPSYFGGYVNANYQAVADALDLSRDDLVTLARNSFTGSFLSDAEKARHLAAIDAYA
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenine to hypoxanthine.  Plays an important role in the purine salvage pathway and in nitrogen catabolism.
What are the official names of this protein?
Adenine deaminase, ADE, Adenine aminohydrolase, AAH.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
Protein: MUTL_COLP3
Sequence: MTIAILPARLANQIAAGEVVERPASVIKELIENSLDAGATSIHIDVDKGGIKKIKITDNGHGIVKEELTLALSRHATSKIKSLNDLEAIGSLGFRGEALASISSVARLTLTSKPQSQATAWQAVAEGRDMSVNIKPAAHPDGTSIEVLDLFFNTPARRKFLRTEKTEFNHIDEVVRRIALAHFEVSFSLTHNGNTVRQYRMASTHAQCIKRVAMVCGPKFIEHAVEVDCPHDNMTLSGWLAKPSFSRSQNDLCYSYVNGRMMRDKLINHAIRQAYADLLPPDTYPAFVLFLQLDHREVDVNVHPSKHEVRFHQSRYVHDFIYSVCHKALTSALAGEELFTTADSDLALVPEQSYSSLGANDRQGSHSSNTPTLNYPSADYIRPLQHVNDASNSQSTSSYSGYGQQHKTNAISKIAASNYQALMTPDKGSSAQVQNTSGSDQASAQKHETTTLQNSTDQSAFLSVHQPGYALYKTENGVRVLSLFKLAKSTYGKLVEQSWQNKTEQSDCPVECLVSQPLLLPVILSLSEQQLSFVLAEQEILSNAGIVFIQQHKNKIQIRQFPALLREQDVSNALIIIIEELIEKRSFTEGEALCETNLHQSIGLAMVLAEYDETQADILLRLTKKLFHEQLSQQLLLNSIPLDLTSHIKTLF
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: EFEO_SHIFL
Sequence: MTINFRRNALQLSVAALFSSAFMANAADVPQVKVTVTDKQCEPMTITVNAGKTQFIIQNHSQKALEWEILKGVMVVEERENIAPGFSQKMTANLQPGEYDMTCGLLTNPKGKLIVKGEATADAAQSDALLSLGGAITAYKAYVMAETTQLVTDTKAFTDAIKAGDIEKAKALYAPTRQHYERIEPIAELFSDLDGSIDAREDDYEQKAADPKFTGFHRLEKALFGDNTTKGMDQYAEQLYTDVVDLQKRISELAFPPSKVVGGAAGLIEEVAASKISGEEDRYSHTDLWDFQANVEGSQKIVDLLRPQLQKANPELLAKVDANFKKVDTILAKYRTKDGFETYDKLTDADRNALKGPITALAEDLAQLRGVLGLD
What is the function of this protein?
Involved in Fe(2+) uptake.  Could be an iron-binding and/or electron-transfer component (By similarity).
What are the official names of this protein?
Iron uptake system component EfeO.
What is the protein family that this protein belongs to?
Belongs to the EfeM/EfeO family.
What are the subcellular locations of this protein?
Periplasm.