PharMolix/UniProtQA huggingface dataset:
Protein: MINE_SHEON
Sequence: MSLLDYFKSKKKPSTAVMAKERLQIIVAHQRGQRDTPDYFPQMKQEIIAVIRKYVQISDDQVSVQLDQNDDNLSVLELNVTLPDR
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: Y254_MYCPN
Sequence: MYARLIAEKLLNHKLTIATAESVTGGLLSSSLTDIAGASRFFKGAIVAYSNELKKSLLNVKQSTLINHGAVSRYCVREMALGLMQKLNVDIAVACSGVAGPDALENQAVGSLFFCVIVANKAYDFETKLPAGSRNELRQLFVQKILQTVEHILSEIS
What are the official names of this protein?
Protein MG115 homolog.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: 3SOF5_NAJAT
Sequence: MKTLLLTMVVVTIVCLDLGYTLKCHNTQLPFIYKTCPEGKNLCFKATLKKFPLKFPVKRGCADNCPKNSALLKYVCCSTDKCN
What is the function of this protein?
Non-cytotoxic protein that does not show lytic and hemolytic activities, but can induce aggregation and fusion of sphingomyelin vesicles (PubMed:8182052).  It binds to integrin alpha-V/beta-3 (ITGAV/ITGB3) with high affinity, and it inhibits osteoclast differentiation and bone resorption in mice, probably due to binding to integrin alpha-V/beta-3 (PubMed:16407244).
What are the official names of this protein?
Cytotoxin A5, CTX A5, CT A5, Cardiotoxin A5, Cardiotoxin V, CTX V, CTXV, Cardiotoxin-like basic polypeptide, CLBP.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Orphan group XV sub-subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: RL36_CHLAB
Sequence: MKVSSSIKADPSKGDKLVRRKGRLYVINKIDPNRKQRQAGPARKK
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: ACSF_SYNE7
Sequence: MVDSLQKPELEELRPGIKAPAKETILTPRFYTTDFEAMAKMDLSPNEDELRAILEEFRADYNRKHFVRTPEFDGSAADMDPETKKVFVEFLEQSCTSEFSGFLLYKELSRRIKNRNPLLAECFELMARDEARHAGFLNKSMSDFDLQLDLGFLTANKKYTYFKPAYIFYATYLSEKIGYWRYITIFRHLEQHPEYRIYPIFKFFENWCQDENRHGDFFDALMKAQPSTVRGFVAKLWCRFFLLAVFATMYIRDVQRKEFYEALGLDAREYDRHVIAKTNETSARVFPVVLDVDHPKFYDRLETCIANNNQLAAIEATSAPKPVKVLRKLPYYLSNGLQLLKLYLVKPLESDVYQPAVR
What is the function of this protein?
Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis.  Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME).
What are the official names of this protein?
Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase, Mg-protoporphyrin IX monomethyl ester oxidative cyclase.
What is the protein family that this protein belongs to?
Belongs to the AcsF family.
Protein: HNF1B_RAT
Sequence: MVSKLTSLQQELLSALLSSGVTKEVLIQALEELLPSPNFGVKLETLPLSPGSGADLDTKPVFHTLTNGHAKGRLSGDEGSEDGDDYDTPPILKELQALNTEEAAEQRAEVDRMLSEDPWRAAKMIKGYMQQHNIPQREVVDVTGLNQSHLSQHLNKGTPMKTQKRAALYTWYVRKQREILRQFNQTVQSSGNMTDKSSQDQLLFLFPEFSQQNQGPGQSEDACSEPTNKKMRRNRFKWGPASQQILYQAYDRQKNPSKEEREALVEECNRAECLQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAYSSNQTHNLNPLLTHGSPHHQPSSSPPNKLSGVRYSQPGNNEVTSSSTISHHGNSAMVTSQSVLQQVSPASLDPGHSLLSPDSKMISVSGGGLPPVSTLTNIHSLSHHNPQQSQNLIMTPLSGVMAIAQSLNTSQAQGVPVINSVASSLAALQPVQFSQQLHSPHQQPLMQQSPGSHMAQQPFMAAVTQLQNSHMYAHKQEPPQYSHTSRFPSAMVVTDTSSINTLTSMSSSKQCPLQAW
What is the function of this protein?
Transcription factor that binds to the inverted palindrome 5'-GTTAATNATTAAC-3' (By similarity).  Binds to the FPC element in the cAMP regulatory unit of the PLAU gene (By similarity).  Transcriptional activity is increased by coactivator PCBD1 (By similarity).
What are the official names of this protein?
Hepatocyte nuclear factor 1-beta, HNF-1-beta, HNF-1B, Transcription factor 2, TCF-2, Variant hepatic nuclear factor 1, vHNF1.
What is the protein family that this protein belongs to?
Belongs to the HNF1 homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: THIE_AZOC5
Sequence: MPHPFDLSLYLVTDRRLTAERGLLETVEEAVAGGVTLVQLRDPEAKGRALAEEARALIGLLRPKGIPLIINDRVDVAAAVGAEGVHLGQDDLDPAAARAILGPDAIIGLSVGSLEELSASNLGPVDYVGCGPINATGTKGDAGGAIGIEGFAFLRSHIALPMVGIGGLKAEDAEAVMQAGANGIAVVSALCAAPDVTEAARTLKTIIETSRR
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: KBRS1_MACFA
Sequence: MGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLYDTRGLQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGNKIDLSEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFPLPGRKNKGNSSSEN
What is the function of this protein?
Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation.  May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit.  It is unclear whether it acts as a GTPase.  Both GTP- and GDP-bound forms block phosphorylation of NFKBIB (By similarity).
What are the official names of this protein?
NF-kappa-B inhibitor-interacting Ras-like protein 1, I-kappa-B-interacting Ras-like protein 1, Kappa B-Ras protein 1, KappaB-Ras1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTPP_RUEPO
Sequence: MTVPLILASGSAIRAQLLENAAVPFTKDVPRVDEESVKAALLAESAPPRDIADALAEMKARKISDKHPGAMVLGCDQVLDFQGRLLSKPDSPETALAELKQMSGQRHMLLSAAVIYENGQPVWRHVGQVRLRMRALSDSYLSGYVARNWDSIRHAVGGYKLEEEGVRLFSTIDGDHFNVLGMPLLELLNFLALRGVIDT
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABZ_SHEPA
Sequence: MSNQLNTMDIKEILKFLPHRYPFLLIDRVLDFTPGETLHAIKNVTINEPFFQGHFPVQPVMPGVLILEAMAQATGLLAFKTMSEEPSNDALYYFAGIDKARFKRVVEPGDQLHFEVQMIKERRGIGVFTGVAKVDGEVVCSAEIMCARREISK
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS4_BRUSI
Sequence: MILFPAIDLKDGQCVRLKLGDMDQATIYNEDPAAQAKAFEDQGFEWLHVVDLNGAFAGESVNGTAVEAILKATKNPVQLGGGIRTLAHIENWLSRGLRRVILGTVAVRDPALVMEACKAFPGQVAVGIDAKGGKVAVEGWAEASRLGVIELAKKFEGAGVAAIIYTDIDRDGVLAGINWDSTLALAEAVSIPVIASGGLASMEDIRRLATPEMRKLEGAISGRALYDGRIDPAEALSVLRAAA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPR19_HUMAN
Sequence: MVFAHRMDNSKPHLIIPTLLVPLQNRSCTETATPLPSQYLMELSEEHSWMSNQTDLHYVLKPGEVATASIFFGILWLFSIFGNSLVCLVIHRSRRTQSTTNYFVVSMACADLLISVASTPFVLLQFTTGRWTLGSATCKVVRYFQYLTPGVQIYVLLSICIDRFYTIVYPLSFKVSREKAKKMIAASWVFDAGFVTPVLFFYGSNWDSHCNYFLPSSWEGTAYTVIHFLVGFVIPSVLIILFYQKVIKYIWRIGTDGRTVRRTMNIVPRTKVKTIKMFLILNLLFLLSWLPFHVAQLWHPHEQDYKKSSLVFTAITWISFSSSASKPTLYSIYNANFRRGMKETFCMSSMKCYRSNAYTITTSSRMAKKNYVGISEIPSMAKTITKDSIYDSFDREAKEKKLAWPINSNPPNTFV
What is the function of this protein?
Orphan receptor.
What are the official names of this protein?
Probable G-protein coupled receptor 19, GPR-NGA.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TX154_LYCSI
Sequence: MKFVLLFGVLLVTLFSYSSAEMFDDFDQADEDELLSLIEKEEARKDCIPKHHECTNNKHGCCRGHLFKYKCQCTTVVTQSGEETERCFCGTPPHHKAAELVVGFGKKIFG
What are the official names of this protein?
U1-lycotoxin-Ls1kk, Toxin-like structure LSTX-A54.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 03 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DXS_RHIWR
Sequence: MNDRPPTPLLDTVSTPEDLRRLKPADLRQLADELRAEMISAVSVTGGHLGAGLGVVELTVALHYVFDTPRDVLIWDVGHQAYPHKILTGRRDRIRTLRQGGGLSGFTKRSESEYDPFGAAHSSTSISAALGFAVANKLANKEGRAIAVIGDGAMSAGMAYEAMNNAKQAGNRLIVILNDNDMSIAPPVGALSAYLAKIVSSRPFLSMRGFAKRVAQKLPRPIHDFAKRSEEYARGMATGGTLFEELGFYYVGPVDGHNLDHLLPILENVRDGDHGPILIHVVTNKGKGYAPAEAAADKYHGVQKFDVVSGVQAKAPPGPPSYTGVFADALVAEAKRDDRICAITAAMPSGTGLDKFGKAFPERSFDVGIAEQHAVTFAAGLAAQGYRPFCAIYSTFLQRAYDQVVHDVAIQNLPVRFAIDRAGLVGADGSTHAGSFDITYLATLPNMVVMAAADEAELVHMVHTAAVHDSGPIALRYPRGNGVGVALPAAPERLAIGKGRIVREGKTVALLSLGTRLGEALRAADQLDALGLSTTVADLRFAKPLDEAMIQTLLTSHEVAVTIEEGAIGGLGAHVLTLASDLGLIDGGLKLRTMRLPDAFQEHDKPEKQYAEAGLDAESIVATVLAALHRNSKGLEESA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: MSCS_EDWI9
Sequence: MKELDVVDGIQSAGGWIVRNQDLLLGYAVNLVAAVVILIIGSLIARGISTTLIRLLKARGLDVTVVHFLAAMVRYAILAFTIIAALGRLGVQTTSVIAVLGAAGLAVGLALQGSLSNFAAGVLLVLFRPFRAGEVVDLGGVTGTVREVQIFSTTLATADNKVIVVPNGKIIAGNIINFSREPKRRIDIIVGVAYDADIDVVKRVLGDVVAADTRILHDDGVTIRLNEMAASSLNFVVRVWGNNADYWAIYFDLMENFKRALDANNIGIPFPQMDVHLYQAVKARAE
What is the function of this protein?
Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins.  Contributes to normal resistance to hypoosmotic shock.  Forms an ion channel of 1. 0 nanosiemens conductance with a slight preference for anions.  The channel is sensitive to voltage; as the membrane is depolarized, less tension is required to open the channel and vice versa.  The channel is characterized by short bursts of activity that last for a few seconds.
What are the official names of this protein?
Small-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscS (TC 1.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DAPF_SHESH
Sequence: MIHFTKMHGLGNDFMVVDGVTQNVFFSPEQIKRLADRNFGIGFDQLLLVEPPYDPDLDFHYRIFNADGGEVEQCGNGARCFARFVRNKGLTNKQKIRVSTSNGKITLRLERDGNVTVNMGIPVLEPGRIPFNAKKMEKTYLLQATNPDSTMQTFLFGAVSMGNPHCVLDVEDIEAADVEGIGALLTRHERFPKGVNVGFMQIINSGHIKLRVYERGAAETLACGTGACAAAVVGQLQGKLDNCVRVDLPGGTLTINWEGEGKPLWMTGPAEHVYDGQIQQ
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y587_MYCPN
Sequence: MVIALKRFSFLASIATLTVLNACATISLSDKSGEFYINNIPSSAELHRINYDLTFSLGFTNRIQTKKKNEVNFVAFYGTGLLIDWKEGNQYQPFRVYLATNVHVAAGLKNEADYLPYSQPDAELGWTVDFRLGKYTNVKDFVSPNENRIT
What are the official names of this protein?
Uncharacterized lipoprotein MPN_587.
What is the protein family that this protein belongs to?
Belongs to the MG067/MG068/MG395 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: NCBP1_ASHGO
Sequence: MSGMKRRYDYEEEDGYRDFRPRYSKRQRLPPVVQLCKDMLPDIRTIGESVKAFEEDIKFLSEAIINEFGNDEYFNNALLSTFNALILEQPHKQPAIALLTIVVNSGNPAAGKSVINYFYEKLQHLLDMTVVDDFEVTSNETGPWNKIKLTLRFLSLLSPVITLTELTNVYQRLFELAVQLNRSSDANTRNPLSEAIYTNTLLNIPYLFFFNKEDETLRTNVEDLIQYAESNYEVKTVDLSLTKEYNKNLPYEPVQWVQIVLSNVKNALANDMEELKNLFPDYQNLLPTSIEQQMFNDPLTIPEFEKLLPFSGLDKGLGSVDSMWKTPRTAFQVYLPNVVGDFSTVVPITTYTGMLFDDIIVDIVESLEFNRHEVARQVVTLDLYFKPGIFTEPGLSIAQLLVQHNEMPELSTYKIEDLAIENILGLIFKLPTVTQSFAYFYTLLVEICQNSPKAIAPVFGRAFRLFYNNLDNMDHELKMRYLDWFSIQMSNFNFSWKWNEWEQDSIAFSKSFYNPKITFAKNLIRKELRLTSNRPDVEDSLTPEFKQYLDASYISKDQLASYYQSFFEGFSFDPEVIKDNDLLFKNEVFPFHEKVQLILDYIHKQPLEKNISELESLLEDIKSAHGDKIPDFNRFTVTLLIQALVYSGNRSLSHANKYISDAKSDLVTILEKMEVPPEVKEQWIIEAVIRYWNCNSQNGFLIVDSFKHSELVTAKSILTFSLTDLNGQNLGLVDATSIESTFRTLTELALQQASDISVFEFVFERLLEIINDTVSQLGTNEEIVAPSVDNETMLDVDELARLDLIWKYESAVGFIKSILRKYSDEYSVLLDKFSAGLEQAVPHEPTRKQLDQWFNEIREL
What is the function of this protein?
Component of the cap-binding complex (CBC) involved in the nuclear export of capped U snRNAs.  The CBC complex is required for efficient pre-mRNA splicing through efficient commitment complex and spliceosome formation; and involved in rRNA processing at sites A0, A1 and A2 (By similarity).
What are the official names of this protein?
Nuclear cap-binding protein complex subunit 1, 80 kDa nuclear cap-binding protein, CBP80, NCBP 80 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the NCBP1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NQRA_SHEAM
Sequence: MITIKKGLDLPIAGGPEQVIHDGPAIKHVATLGEEYIGMRPTMRIKVGDKVAKGQVIFEDKKNPGVKYTALASGTVTEINRGAKRVLQSVVIEIEGNDAVAFDKFDASQLDSLSAEQVRNNLIESGMWTALRTRPFSKVPAVDASPAGIFVTAIDTNPHAANPALVIAGHKDDFANGLKVLAKLTEGKVYLCKAPGADIPAANAEVHEFGGVHPAGLPGTHIHFILPASVTRTVWHVGYQDVIAIGQLFTTGELNNNRVIAIAGPKAVKPRLVRTLLGASIETLTTGEVAEGKVRKVSGSVLHGRTATGPHAYLGRYHLQVSLLEEDTEKEFIGWILPGSNKFSITRAFLGHLSPRRLFNMTTSTGGSDRAMVPIGNYERVMPLDILPTMLLRDLVSGDVDGAVALGALELDEEDLALCTFVCPGKYDYGSYLRGCLDTVEREG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit A, Na(+)-NQR subunit A, Na(+)-translocating NQR subunit A, NQR complex subunit A, NQR-1 subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrA family.
Protein: SFSA_BART1
Sequence: MHFIPKLFPAKLIRRYKRFLADVKQDDQHIFTVSVPNTGSMLGLTASNANIWLSYHENTKRKYAYQLEIVEADNTLVGINTTLPNKLVLEAIQNGLLPELSGYKTILKEQRYGTQSRIDFLLRDDNLPDCYLEVKNVHFIRQKGLAEFPDTETKRGARHLEELMHVVQQGKRAAMLYIIQREDCTAFTICHDLDPLYGRKFDLALKSGVECYAIKCHISVEGIFPIQRVKIENRRNND
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: QACR_STAAM
Sequence: MNLKDKILGVAKELFIKNGYNATTTGEIVKLSESSKGNLYYHFKTKENLFLEILNIEESKWQEQWKKEQIKCKTNREKFYLYNELSLTTEYYYPLQNAIIEFYTEYYKTNSINEKMNKLENKYIDAYHVIFKEGNLNGEWCINDVNAVSKIAANAVNGIVTFTHEQNINERIKLMNKFSQIFLNGLSK
What is the function of this protein?
Transcriptional repressor of qacA.  Binds to IR1, an unusually long 28 bp operator, which is located downstream from the qacA promoter and overlaps its transcription start site.  QacR is induced from its IR1 site by binding to one of many structurally dissimilar cationic lipophilic compounds, which are also substrates of QacA (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator QacR.
Protein: CLPX_DESHD
Sequence: MAKYNDEKNQLKCSFCGKTQDQVKKLVAGPGVYICDECIELCNEIIEEELNEDLGMEIGDIPKPKEIRAILDQYVIGQDEAKKALAVAVYNHYKRINLGMKIDDVELQKSNIVMLGPTGSGKTLLASTLAKVLNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVEKAEKGIVYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQLDTTNILFIVGGAFDGIDKIIQNRIGKKVMGFGAEIKKKSEQNIGETLRELLPADLLKFGLIPEFVGRLPVMVKLDALDEEALVRILTEPKNALVKQYEKLLELDGVALEFKEEALKAIAEEAIRRNTGARGLRAIVEEIMQNVMYDLPSRNDVTKCVVTKDVILKKEEPLLVTIDKSKKNKKEESA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: LPXB_PSEPF
Sequence: MANLRIALVAGEASGDILGAGLMRALKAQHPAVEFIGVGGPLMQAEGLTSYFPMERLSVMGLVEVLGRLRELLKRRKDLIATLIAEKPDVFIGIDAPDFNLNIELKLRQAGIKTVHYVSPSVWAWRQKRVLKIREGCDLMLTLLPFEARFYEEKGVPVRFVGHTLADTIPLEADRAAARAELGLPDGPLVALMPGSRGGEVSRLGALFLDTAQRLRAMRPGVRFVIPCANPERRAQLEELLAGRDLPVTLLDGKSHLALAACNAVLIASGTATLEALLYKRPMVVAYRLAPLTFWILKRMVKSPYVSLPNLLAQRLLVPELLQDDATVEALAQTLSPLIDGGEEQTRGFDEIHRTLRLDASNQAADAVLNLIGQTR
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: OBG_MYCSK
Sequence: MPRFVDRVVIHARAGNGGNGCASVHREKFKPLGGPDGGNGGRGGSIVLVVDPQVHTLLDFHFHPHVVAPSGKQGAGSNRDGAAGADLEVRVPDGTVVLDEEGRVLADLVGAGTRFEAAAGGRGGLGNAALASRSRRAPGFALLGEKGQVRELTLELKTVADVGLIGFPSAGKSSLVSTISAAKPKIADYPFTTLVPNLGVVSAGDHTFTVADVPGLIPGASEGRGLGLEFLRHIERCAVLVHVVDCATMEPGRDPISDIEALEAELAAYRPTLQGDSTLGDLAERPRAVVLNKIDVPDARELADFVRDEVAERFGWPVFEVSTVAREGLRPFIFALWDMVRTYREAQPPVVPRRPIIRPIAVDETGFSVHPDGQGGFVVRGTRPERWINQTDFDNDEAVGYLGDRLARLGVEEELLRLGARPGCAVTIGDMTFDWEPQTPAGVDVQMSGRGTDTRLEQTDRVSAAERKIARRERRQSTDEPGGEE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRAR_STAA8
Sequence: MQILLVEDDNTLFQELKKELEQWDFNVAGIEDFGKVMDTFESFNPEIVILDVQLPKYDGFYWCRKMREVSNVPILFLSSRDNPMDQVMSMELGADDYMQKPFYTNVLIAKLQAIYRRVYEFTAEEKRTLTWQDAVVDLSKDSIQKGDQTIFLSKTEMIILEILITKKNQIVSRDTIITALWDDEAFVSDNTLTVNVNRLRKKLSEISMDSAIETKVGKGYMAHE
What is the function of this protein?
Member of the two-component regulatory system GraR/GraS involved in resistance against cationic antimicrobial peptides (CAMPs) (PubMed:17502406).  Upon phosphorylation by GraS, functions as a transcription regulator by direct binding to promoter regions of target genes such as adhesins, exoproteins, transporters, toxins, and proteins involved in cell wall synthesis.  Down-regulates the expression of many genes involved in RNA and amino acid synthesis or glycolysis (PubMed:17676995, PubMed:18518949, PubMed:24102310, PubMed:25685323).
What are the official names of this protein?
Response regulator protein GraR, Glycopeptide resistance-associated protein R.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_MALP2
Sequence: MKLVLLGAPGCGKGTISDYLVKNYGLVHLSTGDIFRQTIDQKGPYWEELKSYISKGLLVPDELTNKILKNALDKNMDKSFILDGCIRTIAQADFLSTILDIDLALYLEVPFDVLEKRLTGRRICSKCKRIYNIHYSAPKKEDICDDDGEFLIQRKDDQKEIIDERMKVYRTNSEPLIKYYEKLNKLVAINSENLDDLEKNIDDLFINKFNLRKIA
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: U598_CAEEL
Sequence: MILTFARSLYTQGQYNGKIREYFYYVSHNGFLFLDDSRMKNFTAAYKDIQFLNFFYRKIKENKTGRYEDTFPWVSLCGIERNFLRCDDTPLVYTELDSTEKELRIGQSTIYHSFQPSSLSMNSSGRVYHKCPIGGKALVADKLTDKLYRRFRFDDDGVPVGFQCGEQIIELKK
What are the official names of this protein?
UPF0598 protein F59C6.12.
What is the protein family that this protein belongs to?
Belongs to the UPF0598 family.
Protein: MUTS2_CLOBL
Sequence: MKDKSIKVLEFNKIQEILKNYTCTKAAKDIIEDLKPYDSVYEVREHLEEAKEAFKLLITKGAPPFEGVYDIRNGIYLAEKGSALLPGQLLKIAAVLRCARRFKEYINHKEEEESYRVLENICEGIFSLPKIEEEIFNAIEGEDEIADRASSTLYNIRRSLKEKNYSVRDKINSLVRSYSSYLQENIYTVRGDRYVLPVKAEHKGAVPGLVHDQSSTGATLFIEPMSLVNLNNEIKELMLKEKAEIERILTVLSAKINANITGVKTDANIVWELDFIFAKAKFASEYNCTCPTINNEGIVDIIEGRHPLIDRREVVPISVKLGEEFTSLMITGPNTGGKTVTLKTVGLIHLMAMSGLMIPARENSVISYFNNVFADIGDEQSIEQSLSTFSSHMKNIVEIMDKADENSLVLFDELGAGTDPTEGAALAISILENLRKRGTKIIATTHYSELKAYALRKEGVENASVEFDVETLRPTYRLLIGIPGKSNAFEISKRLGLPDYIIDFARENISNENIRFEELIENLQEKSIKAQEDARLAENLKLERDKEKKKYEEKLEGLQKVRDNALIDARREAKNIIKEAKEEADKILKDIRQLERMGYSSDARRKLEEERKKLKDKLDSIEEKEIKTVHKGEALKNVKEGDEVLLASINQKVIVLSKPDNKGDVLVQAGIMKITANIKDLRAAKGSNFNSSSSKIKKSKKLNLNLRRVESSVDLRGMDAEEAIYTVDKYLDEAYLGGLGEVTIVHGKGTGVLRKTIMDMLKGHSHVKRHRLGEYGEGGTGVTVVELK
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.