PharMolix/UniProtQA huggingface dataset:
Protein: HEM1_TRIL1
Sequence: MNIIVVGLSHKTASVDIREKVAFSPNSIEKPLHELVNLDGIVEGIIVSTCNRVEIYATTRDIAGGIARIRRFMAEYHHLAHDLLEPHLYSYHGEEAIRHVFRVASSLDSMVVGEPQILGQIKTSYGYAAEYKSSGIILNRFLHKAFSVAKRVRTETRIASSAVSVSFAAVELARKIFGNLTDKTVLLIGAGEMCELAARHFLTNGAKGVMVTNRTFERAQRLAEEFGGEAIPFDELFLHLHKADIVLTSTGAPHAIITPPDLEEVIKRRRMRPMFLIDIAVPRDIDPAVNEMDAVYLYDMDDLQQVVAANLEGRKQEADKAEAIIAEEIIQFYKWVATLEVTPTIVALRNRFEELRKAELERTLAGWKDAPPDAEKRLEALTSAFMNKLLHQPTTVLKKAGQGNRTDLYLDALRALFDLELGGTDTNESLELEE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: NHAA_FRATO
Sequence: MGASQKNQELIGGLILFSAALLAIVVNNSPLASYYAMLETINVKLGIENLVIDKNLMHWINDGLMAIYFLYIGLEIKREIIVGTLSKLSNIITPAIAAFAGLAMPSLIYLSINHDIKVINGWAIPSATDIAFTLGILALLGTRVPAKLKLLVITIAIFDDIAAIAIIAIFYTKSLSLLSLSLGTLFILAMIICNRIFKINRSSVYVVLGFFAWFCTIKSGVHATLAGFTTALCIPFRENDKDSPANFMEDSLHPWIIYFILPVFAFANAGISFSGISFSILFEPITLGIIWGLFVGKQLGIFSILAVFKKLKWFKLGESFSNLQLYGISLLCGIGFTMSLFIGVLAFNDTHLLNAIKIGVVVGSVLSGFFGYIVLRFIVTNPS
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: STRAB_HUMAN
Sequence: MSLLDCFCTSRTQVESLRPEKQSETSIHQYLVDEPTLSWSRPSTRASEVLCSTNVSHYELQVEIGRGFDNLTSVHLARHTPTGTLVTIKITNLENCNEERLKALQKAVILSHFFRHPNITTYWTVFTVGSWLWVISPFMAYGSASQLLRTYFPEGMSETLIRNILFGAVRGLNYLHQNGCIHRSIKASHILISGDGLVTLSGLSHLHSLVKHGQRHRAVYDFPQFSTSVQPWLSPELLRQDLHGYNVKSDIYSVGITACELASGQVPFQDMHRTQMLLQKLKGPPYSPLDISIFPQSESRMKNSQSGVDSGIGESVLVSSGTHTVNSDRLHTPSSKTFSPAFFSLVQLCLQQDPEKRPSASSLLSHVFFKQMKEESQDSILSLLPPAYNKPSISLPPVLPWTEPECDFPDEKDSYWEF
What is the function of this protein?
Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1.  Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation (By similarity).
What are the official names of this protein?
STE20-related kinase adapter protein beta, STRAD beta, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein, CALS-21, ILP-interacting protein, Pseudokinase ALS2CR2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: TOLB_VIBVY
Sequence: MKKRLLMGLLVLLSSVTNVANAALELIITDGIDSARPIAIVPFKWQGTKALPVDISSVVASDLQRSGKFSPVPTSKMPQTPYNESEINFDAWTNLGVDTLLTGSVTQNEKGEYVINYQLVDVVRGQLTSGQSRALEDGQLVLSKDHVLFNKVATITAPRMREYAHRISDLIYEQLTGERGAFLTRIAYVVVNDKDKFPYQLRVADYDGFNERLVLRSKQPLMSPAWSPDGRQLAYVSFQNGQAEIFVLNIYTGEHEKLTSFPRHNGAPRFSPDGKKLAIVLSKTGSLQIYTLDLQTRQLTQITRDRSNNTEPFWHPDGKSLIFTSDRGGKPQIYRVNLSDGSTSRLTWQGSQNLGGQITPDGRFLIMVNRSDSGFNLAKQDLETGAVQVLTKTLLDESPSIAPNGGMVIYSSIYDKKNVLSMVSIDGRFKARLPATNGRVRAPAWSPFL
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: OBG_MOOTA
Sequence: MFYDEAKIYVKGGDGGNGIVAFRREKYVPRGGPNGGDGGRGGSVILEADAGLRTLVDFRYRAHYRAERGQHGQGKNKHGRSAPDLILRVPVGVVVRDATSGQVLADLVEDGQRVVVAAGGRGGRGNARFVTSTDRAPTFAEKGEPGEERWLVLELKLLADVGLIGLPNAGKSTLLARISAARPKIADYPFTTLTPNLGVVRLEDGDSFVVADIPGLIAGAHQGAGLGLKFLRHIERTRVLVHVLDTSQPGEDVLAGWRTVNDELAHYNPELARRPQVVAANKMDIPGGEEKVAFLRERLGDSYRIFPISAATGEGVQELLYHVSGLLATLPPPAPVTAPEEEKVTALAPEELTIEREGQVFIVKNPDVERRVAMTYLDNEEAVRRLQVYLKQKGVDDALRRAGAATGAIIRIGKFEFEYVEEP
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIM1_CRYNH
Sequence: MFALKSILVTSLITSTALAHFTLDYPQSRGFVDDTENQFCGGFNTVEARQPFPLGSGPVHIDSHHALATIVAFISTSSNPTSFDDFNTTSNGTAIPLASSIFQVPQGEKCFNIDLQSLNVGLTNGSEVTLQIQYDGGDGNLYQCSDLVLIEGYEVPSNETCTNDASKASNATSTSSGSATATSAAATSSSSGTSGAIKEVVGFGALSLALGIAGLIIL
What is the function of this protein?
Cell surface-bound protein that functions in the copper-accumulation pathway shared by the CUF1-dependent copper transporter CTR1 (PubMed:31932719).  Binds Cu(2+) with an estimated 1:1 stoichiometry and might serve as an extracellular copper ligand (PubMed:31932719).  FRE4 and FRE7 metalloreductases probably function together with CTR1 and BIM1 to liberate the Cu(2+) bound to the BIM1 copper-binding site for subsequent import of Cu(+) into the cell by CTR1, via the reduction of BIM1-bound Cu(2+) to Cu(+) to reduce binding affinity for BIM1 but increase affinity for CTR1 (Probable).  Facilitates copper acquisition in the brain of mammalian hosts and acts as a copper-dependent virulence trait in fungal meningitis (PubMed:31932719).  While BIM1 plays a critical role in cryptococcal meningitis, at least in part through its role in copper acquisition, it could play additional roles during copper limitation or as a means to invade and colonize host tissues in the brain, by compromising host carbohydrate integrity via its lytic polysaccharide monooxygenase (LPMO) activity, which has still to be determined (Probable).
What are the official names of this protein?
Copper acquisition factor BIM1, BCS-inducible membrane protein 1, Lytic polysaccharide monooxygenase-like protein BIM1, LPMO-like protein BIM1.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: MCCA_BACSU
Sequence: MTVITDITELIGNTPLLRLKNFDVPEGVAVYAKLEMMNPGGSIKDRLGDMLIRDALDSGKVKPGGVIIEATAGNTGIGLALSARKYGLKAIFCVPEHFSREKQQIMQALGASIIHTPRQDGMQGAIQKAIQLETEIENSYCVLQFKNRVNPSTYYKTLGPEMWEALDGNIHTFVAGAGSGGTFAGTASFLKEKNPAVKTVIVEPVGSILNGGEPHAHKTEGIGMEFIPDYMDKSHFDEIYTVTDENAFRLVKEAAEKEGLLIGSSSGAALYAALEEAKKASAGTNIVTVFPDSSDRYISKQIYEGGI
What is the function of this protein?
Catalyzes the conversion of O-acetylserine and homocysteine to cystathionine.
What are the official names of this protein?
O-acetylserine dependent cystathionine beta-synthase.
What is the protein family that this protein belongs to?
Belongs to the cysteine synthase/cystathionine beta-synthase family.
Protein: ALA11_ARATH
Sequence: MTKCRRRRLHLSNIYAFKGRKSNFQEDHSHIGGPGFSRVVYCNEPNSPAAERRNYVGNYVRSTKYTLASFIPKSLFEQFRRVANFYFLVTGVLSLTALSPYSPISALLPLTFVIAASMVKEAIEDWGRKKQDIEMNNRKVKVHDGNGIFRREGWRDLKVGNIVRVEKDEFFPADLLLLSSSYEDSICYVETMNLDGETNLKVKQGLEATSSALHEDSDFKELKAVVKCEDPNADLYTFVGTLHFEEQRLPLSITQLLLRDSKLRNTEYIYGVVVFTGHDTKVIQNSTDPPSKRSRIERKMDKIIYLMFGVVFLMSFIGSIVFGIETREDRVRNGGRTERWYLRPDNADIFFDPDRAPMAAVYHFFTAVMLYSYFIPISLYVSIEIVKVLQSLFINNDILMYYEENDKPAHARTSNLNEELGMVDTILSDKTGTLTCNSMEFIKCSIAGTAYGRGITEVERSMAMRSNGSSLVGDDLDVVVDQSGPKIKGFNFLDERVMKGNWVKQRDAAVLQKFFRLLAVCHTAIPETDEATGSVSYEAESPDEAAFVVAAREFGFEFFSRTQNGISFRELDLASGKTVERVYRLLNVLEFNSARKRMSVIVRDEDGRLLLLSKGADNVMFERLAKNGRKFEEKTREHVNEYADAGLRTLILAYREVDENEYIEFSKNFNEAKNSVTADRESLIDEITEQMERDLILLGATAVEDKLQNGVPDCIDKLAQAGIKIWVLTGDKMETAINIGFACSLLRQEMKQIIINLETPHIKALEKAGEKDAIEHASRESVVNQMEEGKALLTASSSASSHEAFALIIDGKSLTYALEDDFKKKFLDLATGCASVICCRSSPKQKALVTRLVKSGTGKTTLAIGDGANDVGMLQEADIGVGISGVEGMQAVMSSDIAIAQFRYLERLLLVHGHWCYSRISSMICYFFYKNITFGVTVFLYEAYTSFSAQPAYNDWFLSLFNVFFSSLPVIALGVFDQDVSARYCYKFPLLYQEGVQNLLFSWKRIIGWMFNGVFTALAIFFLCKESLKHQLYNPNGKTAGREILGGTMYTCVVWVVNLQMALAISYFTWLQHIVIWGSVAFWYIFLMIYGAITPSFSTDAYKVFIEALAPAPSYWLTTLFVMFFALIPFFVFKSVQMRFFPGYHQMIQWIRYEGHSNDPEFVEMVRQRSIRPTTVGFTARRAASVRRSGRFHDQLNKNFIAF
What is the function of this protein?
Involved in transport of phospholipids.
What are the official names of this protein?
Probable phospholipid-transporting ATPase 11, AtALA11, Aminophospholipid flippase 11.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FEV_DANRE
Sequence: MKAYPFTSTTATTMRQNCGGSLMFNMYLSDPTENLLKESKSPSWTPINTGVQKGSGQIQLWQFLLELLSDSANMTCIAWEGTNGEFKLIDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFNGLAQVCQPSSTEQAIYKFQSNFAPIQFSGISKLNLVAPGVGPSGFSYWPGSPPTLYHSHNLQPPGPFGAVSASHLSCVNNINSLNNLNNINNHYN
What is the function of this protein?
Functions as a transcriptional regulator.  Functions in the differentiation and the maintenance of the central serotonergic neurons.  May play a role in cell growth (By similarity).
What are the official names of this protein?
Protein FEV, Protein Pet-1.
What is the protein family that this protein belongs to?
Belongs to the ETS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RECO_SHIFL
Sequence: MEGWQRAFVLHSRPWSETSLMLDVFTEESGRVRLVAKGARSKRSTLKGALQPFTPLLLRFGGRGEVKTLRSAEAVSLALPLSGITLYSGLYINELLSRVLEYETRFSELFFDYLHCIQSLAGDTGTPEPALRRFELALLGHLGYGVNFTHCAGSGEPVDGTMTYRYREEKGFIASVVIDNKTFTGRQLKALNAREFPDADTLRAAKRFTRMALKPYLGGKPLKSRELFRQFMPKRTVKTHYE
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: Y1164_SYNY3
Sequence: MKHVFSGFQTFLKQVHSPIYLALAVVIFSAANPVTSRIIELGKTYEINGRNPISFCNVLFVGNLCALGLMILIFHPDWQLHKLRKLTRKDWFLLTVTAILSRAIAPGLMFSALEKTNVTNVVLIGRLEPVFTLILSILLLKISVNWLSMVATLISFVGVAVTVFWGVADPLDMVINFDFGLGESFVAIAAFISAITTILSKQQLQSIPVGIFTVYRSLLGTFVFFWIAVIIYGFDHFMDVSSPILWRWMLIYGAIIVVVGQVAWLAGLKNASFIQINLASLVTPILAIIFAYLILLETPTNAQYLGGILLLLGAILSFIDNLKTAKDKQASKPLNSREAMDTNVGFRGV
What are the official names of this protein?
Uncharacterized transporter sll1164.
What is the protein family that this protein belongs to?
Belongs to the EamA transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRPF_LIPST
Sequence: MTVSTTSLCTPIVKICGLTVEAAHCAISSGADLIGMILVPDLKRTVQQTKLKAISRAVTRIPGVPTSPSRGIDRPSHGLVRGTFSADYTSWPLVVGVFRNQSLDEVLRMLRNYDLDIVQLHGSEPLHQWTREIPVPVIKKFGLGEDDLMAPGLHAVTLLDGGAGGEGQKISWEGLPGSGAFMLAGGLTVDNVAVAVKIPNVAGVDVSSGVATDGMQDLEKNCRCLFRNAKGW
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: RL22_ALTMD
Sequence: MEALAKHRFARTSAQKARLVADQIRGLHVEKALEVLAYSPKKSAALVKKVLESAIANAEHNEGADIDELVVAKVFVDEGPTMKRIKPRAKGRADRIFKRSSHITVVVADN
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: PHOSP_PI3H4
Sequence: MESDAKNYQIMDSWEEEPRDKSTNISSALNIIEFILSTDPQEDLSENDTINTRTQQLSATICQPEIKPTETSEKVSGSTDKNRQSGSSHECTTEAKDRNIDQETVQGGSGRRSSSDSRAETVVSGGISGSITDSKNGTQNTENIDLNEIRKMDKDSIERKMRQSADVPSEISGSDVIFTTEQSRNSDHGRSLEPISTPDTRSMSVVTAATPDDEEEILMKNSRMKKSSSTHQEDDKRIKKGGGGKGKDWFKKSRDTDNQTSTSDHKPTSKGQKKISKTTTTNTDTKGQTETQTESSETQSPSWNPIIDNNTDRTEQTSTTPPTTTPRSTRTKESIRTNSESKPKTQKTIGKERKDTEESNRFTERAITLLQNLGVIQSTSKLDLYQDKRVVCVANVLNNVDTASKIDFLAGLVIGVSMDNDTKLIQIQNEMLNLKADLKRMDESHRRLIENQREQLSLITSLISNLKIMTERGGKKDQNESNERVSMIKTKLKEEKIKKTRFDPLMEAQGIDKNIPDLYRHAGNTLENDVQVKSEILSSYNESNATRLIPRKVSSTMRSLVAVINNSNLPQSTKQSYINELKHCKSDEEVSELMDMFNEDVNNC
What is the function of this protein?
Essential component of the RNA polymerase and the nascent chain assembly complex.  Also required during RNA synthesis.
What are the official names of this protein?
Phosphoprotein, Protein P.
What is the protein family that this protein belongs to?
Belongs to the respirovirus P protein family.
Protein: DB119_HUMAN
Sequence: MKLLYLFLAILLAIEEPVISGKRHILRCMGNSGICRASCKKNEQPYLYCRNCQSCCLQSYMRISISGKEENTDWSYEKQWPRLP
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Beta-defensin 119, Beta-defensin 120, Beta-defensin 19, DEFB-19, Beta-defensin 20, DEFB-20, Defensin, beta 119, Defensin, beta 120, ESC42-RELA.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PUR7_NEIMB
Sequence: MSEIGLVKIYFGKVRDLYEIDDKRMLMVASDRLSAFDVILDDPIPSKGEILTQISNFWFKKLAHIMPNHFTGQTVYDVLPENEAKALEKRAVVAKKLTPVKVEAIVRGYLAGSGWKDYQKTGSVCGIQLPEGMQEAQQLPEVIFTPSTKAAVGDHDENISFEECGRIIGKELAEEVRAKAVRLYTEAAEYAKSRGIIICDTKFEFGLDENGTLTLMDEVLTPDSSRFWPADQYKVGTNPPSFDKQFVRDWLEQSGWNKKAPAPKVPADVIQKTVEKYREALTLLTQD
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: AROB_PYRAB
Sequence: MENIIFSPLSSLPSIVEELNPYKIAVLTNDMLKSLWLDKIIELLGGDVFPIVIPDGEEYKTIETAIKIWDELVSFGFTRKSLLIGLGGGVITDIAGFVASTYMRGTLLGFIPTTLLAQVDAAIGGKTGVNFHGKNMIGTFYLPNFVLISTETLSTLPRIELLNGMAEVIKYAILDKNVYRLLQDVKNVEEIRNREDIIRESVNVKVRVVEEDLKESGKRRILNLGHTVGHAIEKLSGYKIKHGFAVSVGLIAAAKLGEKLYNFDSGKVIELVERFNLPTKLPYPPKDIIEAMKLDKKAWYGKIVFVIPVEIGRISIEDVPEELLLQVLGEIR
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DC1I1_MOUSE
Sequence: MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALLQSIGISPEPPLVPTPMSPSSKSVSTPSDAGSQDSGDLGPLTRTLQWDTDPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVEPKIGHDSELENQEKKQETKEAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYSNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNSDTEVPTASVAIEGASALNRVRWAQGGKEVAVGDSEGRIWIYDVGELAVPHNDEWTRFARTLVEIRANRADSEEEGAVELAA
What is the function of this protein?
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function.  Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.  The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCTN1.  May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.
What are the official names of this protein?
Cytoplasmic dynein 1 intermediate chain 1, Cytoplasmic dynein intermediate chain 1, Dynein intermediate chain 1, cytosolic, DH IC-1.
What is the protein family that this protein belongs to?
Belongs to the dynein intermediate chain family.
What are the subcellular locations of this protein?
Cytoplasm. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle pole.
Protein: MSH3_PICGU
Sequence: MKRGIDIVQALKNSKRSKSSDDSVESKLSKASPDLSQYAAVQISKEDVTVNPEVKSTIDNHKKEPPSIASSIKKSPKTVIGKHANSTKKPKKRTPLDQQFIDLKNEYPDCVLAIQVGYKYKFFGVDAVPVSRILNIMFIPGNLTERDATHDKFAYCSVPDNRLHIHLQRLLTNGLKVAVVSQTESAVLREAESSKGLFLREVTAIYTKATYIEEGSGDFISCITWNGTSAGAVTVQPCTGEIIVEDFSEKEPEALSELQTYLHHLRPSEIIVTDNEATKENDKLSRLLKSFGGARISYKPFDEVSPIEELLPASIANYYVTNHSTTTTQCISQLITYLKDFSLDQIFTVPSNVSKFSTKMYMNLPGNTLKALEIFQNSSGTEKGTLFWHLDHTHTKMGRRMLQKWVSKPLIDNASIQERLDAIESLMNYNYAVEVFEGIIKKIGRDESDWEKSMIKIHYTANGSQNRVTRKEVVQLLLQFRSVIDTVYKFKSSFKDSSISKLLQSMFSELAELASTPIVNDLLSRVKIEAVYREEVEDQKKEFFDLDSHPHEGIKSELNAISELEQALQDELVEIKKIIKKPVDYMTVSREPYLIALRGDSGPQDWLKISATKTVTRYRPPKVSKLYKELLYHQEKLIQQCDEAFATFLKDIDSHYTYFSRLIKIVAEIDCLLSLKATSSSNSGYSKPILSDKQMIKAKRSRNPVIENLTSTSQYVANDIEISYDENRVLIITGPNMGGKSSYVKQVALIALMTQIGCYLPCESAIVGIFDTILVRMGAEDNILKGESTFMVEMSECSTIIKSLTNKSLVILDEIGRGTGTEDGIAIAYSIISYLIEEPRLPLTLFITHYPSLKVLEDTHPKNVANYHMGFMEVAKADQEWPDVTFLYTLKRGVVSNSYGLNVARLAGIPSEIITKAFKVAEALKQDIEDSELSSMGQILKSEQSSASKLVEIDRIVSYI
What is the function of this protein?
Component of the post-replicative DNA mismatch repair system (MMR).  Heterodimerizes with MSH2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair.  MSH3 provides substrate-binding and substrate specificity to the complex.  When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs.  Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication.  After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.  ATP binding and hydrolysis play a pivotal role in mismatch repair functions (By similarity).
What are the official names of this protein?
DNA mismatch repair protein MSH3, MutS protein homolog 3.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MSH3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PA2HD_TRIST
Sequence: MRTLWIMAVLLLGVEGHLLQLRKMIKKMTNKEPILSYGKYGCNCGMAGRGQPVDGTDRCCSIHNCCYGKVNGCSPKWDYYTYSEENGDIVCEEKHPCKDVCECDKAVATCFRDNLDTYKKRNIFHPKSSCVKVSTPC
What is the function of this protein?
Snake venom phospholipase A2 homolog that induces local edema a few hours after injection (5-10 ug) in the hind paw and shows weak anticoagulant and myotoxic activities.
What are the official names of this protein?
Basic phospholipase A2 homolog Ts-R6, svPLA2 homolog, CTs-R6, PLA2-I.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. N49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: REX_STRZT
Sequence: MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIGIDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLHYRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSVKSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_PETMA
Sequence: MTLDIFDQFTSPTMFGLPLAWLAMLAPSLMLVSQTPKFIKSRYHTLLTPILTSIAKQLFLPMNQQGHKWALICMASMMFILMINLLGLLPYTYTPTTQLSMNMGLAVPLWLATVLIGLQKKPTEALAHLLPEGTPAALIPMLIIIETISLFIRPIALGVRLTANLTAGHLLMQLVSMTTFVMIPVISISIITSLLLLLLTILELAVAVIQAYVFILLLTLYLQENVYVPPSSCMPHG
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, F-ATPase protein 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RS10_VIBVU
Sequence: MQNQRIRIRLKAFDYKLIDASTAEIVETAKRTGAQVRGPIPLPTRKERFTVLISPHVNKKARDQYEIRTHKRLIDIVEPTDKTVDALMRLDLAAGVDVQISLG
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: HSCB_ECOLC
Sequence: MDYFTLFGLPARYQLDTQALSLRFQDLQRQYHPDKFASGSQAEQLAAVQQSATINQAWQTLRHPLMRAEYLLSLHGFDLASEQHTVRDTAFLMEQLELREELDEIEQAKDEARLESFIKRVKKMFDTRHQLMVEQLDNETWDAAADTVRKLRFLDKLRSSAEQLEEKLLDF
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB, Hsc20.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: RNP2_HALSA
Sequence: MKHLPKHVRPRWRYLAVGIEAWPDAGIERSDFQRALWFAAGNLLGDPGSADAGVRVVAYSFRDGRGEALVRARRGTVSRARAAVACVSAVREHPVRVCVRGVSGTMRAARERYLDGLDTPERRSDVAFDGDARDGVCRGENVDVVAGDDGWVGARRRDCGTDGE
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 2, RNase P component 2, Pop5.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU4LM_PHYIN
Sequence: MSILNHFIFTFFLFCLGLFGIILNRQNIIIILMSIELLLLSINLNFIYFAVLIDDIIGQVFSLLILTVAAAESAIGLAIMIVFFKLYGDISIYKINLLSL
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: SYFA_VIBCH
Sequence: MQHLQEIIANATSAINAAESLVALDEVRVQYLGKKGELTVQLQSLGKLPPEERRTAGQEINVAKEAVQKALAERKDALQSAELEAKLAAETIDVTLPGRRIENGGLHPVTRTIERIESFFGELGFTVESGPEIEDDFHNFDALNIAADHPARTDHDTFFFNPKLMLRTHTSGVQIRTLEERQPPLRFIAPGRVYRNDYDQTHTPMFHQVEGMLVDENVNFAQLKGILHDFLCNFFEEDLEVRFRPSYFPFTEPSAEVDVKGKNGKWLEVLGCGMVHPNVLRSVGIDPEKYSGFAFGMGVERLTMLRYGVNDLRAFFENDLRFLKQFK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.