PharMolix/UniProtQA huggingface dataset:
Protein: DGCR8_MOUSE
Sequence: METYESPSPLPREPAGEAMMENRACPFQVLPHEQSPPPPLQTSSDAEVMDVGSGGDGQSEPPADDPFNFYGASLLSKGSFSKGRLLIDPNCSGHSPRTARHAPAVRKFSPDLKLLKDVKISVSFTESCRSKDRKVLYTGVERSTRPECGQLLSPVSGDVHACPFGGSVGNGVGLGGESADKKDEENELDQEKRVEYAVLDELEDFTDNLELDEEGTGGFTAKAIVQRDRVDEEALNFSYEDDFDNDVDALLEEGLCAPKKRRMEEKYGGDSDHPSDGETSVQPMMTKIKTVLKSRGRPPTEPLPDGWIMTFHNSGVPVYLHRESRVVTWSRPYFLGTGSIRKHDPPLSSIPCLHYKKMKDNEEREQNCDLAPSGEVSPVKPLGRSAELDFPLEEPDSMGGDSGSMDEKDPLGAEAAAGALGQVKAKVEVCKDESVDLEEFRNYLEKRFDFEQVTVKKFRTWAERRQFNREMKRKQAESERPILPANQKLITLSVQDAPTKKEFVINPNGKSEVCILHEYMQRVLKVRPVYNFFECENPSEPFGASVTIDGVTYGSGTASSKKLAKNKAARATLEILIPDFVKQTSEEKPKDSEELEYFNHISIEDSRVYELTSKAGLLSPYQILHECLKRNHGMGDTSIKFEVVPGKNQKSEYVMACGKHTVRGWCKNKRVGKQLASQKILQLLHPHVKNWGSLLRMYGRESSKMVKQETSDKSVIELQQYAKKNRPNLHILSKLQEEMKRLAAEREETRKKPKMSIVASAQPGGEPLCTVDV
What is the function of this protein?
Component of the microprocessor complex that acts as a RNA- and heme-binding protein that is involved in the initial step of microRNA (miRNA) biogenesis (PubMed:17259983).  Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus.  Within the microprocessor complex, DGCR8 function as a molecular anchor necessary for the recognition of pri-miRNA at dsRNA-ssRNA junction and directs DROSHA to cleave 11 bp away form the junction to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs.  The heme-bound DGCR8 dimer binds pri-miRNAs as a cooperative trimer (of dimers) and is active in triggering pri-miRNA cleavage, whereas the heme-free DGCR8 monomer binds pri-miRNAs as a dimer and is much less active.  Both double-stranded and single-stranded regions of a pri-miRNA are required for its binding.  Specifically recognizes and binds N6-methyladenosine (m6A)-containing pri-miRNAs, a modification required for pri-miRNAs processing (By similarity).  Involved in the silencing of embryonic stem cell self-renewal (PubMed:17259983).
What are the official names of this protein?
Microprocessor complex subunit DGCR8, DiGeorge syndrome critical region 8 homolog, Gy1.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Note=Colocalizes with nucleolin and DROSHA in the nucleolus. Mostly detected in the nucleolus as electron-dense granular patches around the fibrillar center (FC) and granular component (GC). Also detected in the nucleoplasm as small foci adjacent to splicing speckles near the chromatin structure. Localized with DROSHA in GW bodies (GWBs), also known as P-bodies.
Protein: SYP_SULIK
Sequence: MQITREKWSKNFSEWFDWVLREGEFYDYGRYPVKGMGVWMPYGFKLRQNIISIIRNLLDSTGHEEVLFPLLIPEDLLSRESTHIKGFEEEVFWVTKGGSEDLDVKLALRPTSEVAITTMENLWLKSYKQLPKKYYQIVSVFRYETKATRPMIRLREITTFKEAHTVHETYDDAQRQVEEAIEIYKKIFNNLTIPYVLSERPEWDRFAGALHTYAFDTIMPDGKVMQIGTVHHLGQNFSRALDFKIQKKDGSLDYPHQTSYGISDRAIASVIAIHGDDHGPILPPSVAPIKVVVVPIPAKNEEGTQQVMKYSIEICEMLNKNNITCVTDQDTEKTPGEKFYIWEIKGVPIRLEIGPRELASSTVFIKRRDNLKSYTVKKEEVVNKVKEVLNEIQEDLRKRAWESLKSRIEYANDIEKAKNILENNSGIVEVPWCGSKECGLKIEELTNARVLGYPIEDRKVNDKCVICKMNAKTVLRVAKTY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU_PHOV8
Sequence: MAKEKFERSKPHVNIGTIGHVDHGKTTLTAAITTVLAKKGLSELRSFDSIDNAPEEKERGITINTSHVEYQTANRHYAHVDCPGHADYVKNMVTGAAQMDGAIIVCAATDGPMPQTREHILLARQVNVPRLVVFLNKCDMVDDEEMLELVEMEMRELLSFYDFDGDNTPIIRGSALGALNGVPQWEDKVMELMDAVDTWIPLPPRDIDKPFLMPVEDVFSITGRGTVATGRIEAGIIHVGDEVEILGLGEDKKSVVTGVEMFRKLLDQGEAGDNVGLLLRGIDKNEIKRGMILCKPGQVKAHSKFKAEVYILKKEEGGRHTPFHNKYRPQFYLRTMDCTGEITLPEGTEMVMPGDNVTITVELIYPVALNVGLRFAIREGGRTVGAGQITELLD
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CNPD3_FIBSS
Sequence: MYILRSCMEKKVLKIGQISDAHIGDDDRLVQDIDVRKNFLTAYNSESMKDLDLLVLSGDLADNASTDAYSFIAGVIKDSKVPVCIIPGNHDNLEVMEKVFDLKDKVHNGKCYYRYDLDGRSIFFLDSADGTVSSDQLSWLEQETAKIDGEVLLFLHHPPCLCGHKFMDLRYSMKNIAEVQATLSKIKNLKHIFVGHYHSEMTIQLEDKTVYVTPSTQMQIDPNITVFCLSSAAPRWRLIEWGENFMETKVYFSNTP
What are the official names of this protein?
Probable cyclic nucleotide phosphodiesterase Fisuc_1441/FSU_1912.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase class-III family.
Protein: MNMC_SHELP
Sequence: MPNIPLRVNSLATEHPNNAQNSDKMPTFDAIFSHLSAIASHNSHQIIALLPSSDANWPAALIAERLTQAGSKQHLQKQHLHLHLFAQHQASWLKALAESETLASPAKEQIKAICDARVSGSHRLKLVNARLIIDIHLGDPLTQLKDLVSPSLASQAIQGWLANTQATDEALIWQMARLSQDNAEFLLLENNDVNLDKTSNNANTNLLTQLIIKAGFTCYRLNLSLKDDQLVTLAEKPSLASLEIAMVERRALRRQQLDKFAFNPLTQGREGETAIIGGGVASANLALSLAERGKKVSFFCMDKAPGEQASGNKQGAIYPLLTPEHGSLSHYFLLGYLFSRQRIKQLLESGHEIPHDFCGVLQTGHDERSHKRLTKIINAQPWAESIARPVDALQATALAGVTIEHQGIYYPLAGWVSPQAFTRAAISQAERLGKQTSHYQCQITAIRFENQQWYLSAIQDGQKVEFGPYANLVLANGRHLTDFAQTDHLPISGFRGQVSHIPERAPLKDLKTVLCAHGYLTPAHDKLHCTGASYVKDASNLDYSAVEQVENLDKIRTSYGGEWTKAVDITGHSARVGVRMVTRDHAPMMGCAPDFEAISATYISHQQTKKSTKESAKCWQTTSAPVHQGLFILGGLGSRGLTSGPLAAEILAAQLCGELLPATQDILALLNPNRMWMRKLIKGKAL
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCE1_HUMAN
Sequence: MAHNKIPPRWLNCPRRGQPVAGRFLPLKTMLGPRYDSQVAEENRFHPSMLSNYLKSLKVKMGLLVDLTNTSRFYDRNDIEKEGIKYIKLQCKGHGECPTTENTETFIRLCERFNERNPPELIGVHCTHGFNRTGFLICAFLVEKMDWSIEAAVATFAQARPPGIYKGDYLKELFRRYGDIEEAPPPPLLPDWCFEDDEDEDEDEDGKKESEPGSSASFGKRRKERLKLGAIFLEGVTVKGVTQVTTQPKLGEVQQKCHQFCGWEGSGFPGAQPVSMDKQNIKLLDLKPYKVSWKADGTRYMMLIDGTNEVFMIDRDNSVFHVSNLEFPFRKDLRMHLSNTLLDGEMIIDRVNGQAVPRYLIYDIIKFNSQPVGDCDFNVRLQCIEREIISPRHEKMKTGLIDKTQEPFSVRNKPFFDICTSRKLLEGNFAKEVSHEMDGLIFQPTGKYKPGRCDDILKWKPPSLNSVDFRLKITRMGGEGLLPQNVGLLYVGGYERPFAQIKVTKELKQYDNKIIECKFENNSWVFMRQRTDKSFPNAYNTAMAVCNSISNPVTKEMLFEFIDRCTAASQGQKRKHHLDPDTELMPPPPPKRPRPLT
What is the function of this protein?
Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphate monophosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part.  Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the GMP moiety of GTP to the 5'-diphosphate terminus of RNA via a covalent enzyme-GMP reaction intermediate.
What are the official names of this protein?
mRNA-capping enzyme, HCAP1, HCE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the eukaryotic GTase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: F16PA_PARL1
Sequence: MSQRTLTQFLIEQQRKEAALPAQLRLLVEIVARACKTISHCVNKGALGGMLGNLTSENVQGEVQKKLDVIANEKLLEANEWGGHLAAMASEEMETIHLIPNRYPKGEYLLLFDPIDGSSNIDVDLSVGTIFSVLTAPEDVSGRAVTEADFLQPGRKQVAAGYAIYGPQTLLILSVGTGVYEFALDREMGSWVLTNERIRIPSGNREFAINMSNMRHWAPPVRRYIDECLAGTTGPREANFNMRWTASMVADIHRILKRGGIFMYPWDAREPDRAGKLRLMYEANPMGFLIEQAGGMAFDGNHRILDIEPKALHQRVGVVMGDRDEVKRVVQYHHDANLAKQTA
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_BIFLO
Sequence: MKRTFQPNNRRRHMKHGFRLRMRTRSGRAVINRRRAKGRKTLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: SYL_KINRD
Sequence: MRDARTHREDEMTQTDTQATGPDRAEEQDGQRYDAFALQEKWLPVWDERKPFRSGEPGDERPKKYVLDMFPYPSGDLHMGHAEAYALGDVIARYWLQRGFDVMHPIGWDAFGLPAENAAIKRGLDPRRWTYDNIAQQRASMRRYACSFDWDRVLHTSDPEYYRWNQWLFLKLYEKGLAYRKDSLVNWDPVDQTVLANEQVLPDGTSERSGAKVVKKKLTQWYFRITEYADRLLDDLDTLEGQWPAKVISMQRNWIGRSTGAEVEFAIEGRDEPVTVYTTRPDTLHGATFMVVAADSDLAEELAAGAPDDVRAAFEAYRTQVQETSDIDRLSSEREKTGVPLGRYAVNPVNGERLPIWAADYVLADYGTGAIMAVPAHDQRDLDFARAFGLPVRVVVDVRDDDGNPLPDPAESGTATAGDGVLVNSGALDGLGKQAGIAKAIEDLTAAGKGRAAKNYRLRDWLISRQRYWGTPIPVVHTENGEVPVPEDQLPVLLPPSEGLNLTPKGTSPLGAAEDWVNVPSPVDGSPARRDPDTMDTFVDSSWYFLRFVSPHDDTKAFDTDLIAQWGPVDQYVGGVTHAILHLLYARFITKVLHDLGYLPFDEPFTRLLNQGMVQMDGSAMSKSKGNIVRLSDQLEEHGVDAIRLTMAFAGPPEDDIDWADVSPSGSAKFLGRAWRLARDVTSEPGVDPTTGDAALRSVTHRTLHEVSQHVEAFRFNVAVARLMELVNATRKAIDSGPGAGDPAVREAVEATAVVLSLFAPYAAEDMWSLLGHDPCVARAGWPAVDESLLVQDTVTCVVQVQGKVRDRLEVSPDITQDALRELALASEKVQAALGGRDLRTVVVRAPKLVNIVPA
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_SHEB2
Sequence: MKPLNIIFAGTPDFAARHLQALLNSHHNVIGVYTQPDRPAGRGKKLTASPVKELAVANNIPVYQPGSLRKEPAQQELAALNADIMVVVAYGLILPKVVLDTPRLGCINVHGSILPRWRGAAPIQRALWAGDKETGVTVMQMDVGLDTGDMLLKTYLPIEDSDTSASLYEKLAEQGPVALLQALEGLANGTLAAEKQDEALANYAEKLSKEEARLDWNKSAKQLWQEVRAFNPWPVSYFEHQGNTIKVWQTQVSETTSTAAPGTIISASKKGIEVATADGVLTLLSMQLPGKKPLNVADILNARGEWFSPNTRLANEAQ
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: IF3_PARMW
Sequence: MPPRPRFDRRAPVRELPNINDRISYPQLRVVDSDGSQLGVISREEALEVAKERELDLVLVSEKADPPVCRIMDYGKFKFEQEKKAKEAKKKSHQTEVKEVKMRYKIDQHDYDVRIGQAVRFLKAGDKVKCTVIFRGREIQHTALAETLLRRMAKDLEEKAEIQQAPKREGRNMIMFLTPRKTPLVKKEEKEAAPTKAVRTIPAPPRPTAAKVAAQQA
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INPP_ENTH1
Sequence: MQTSLFEFANVLITAVKEASYSISKFKEEVEIKYKSDGSEVTQVDTQSQQIIFSIIKNKYPTINIIGEEDVENGIPDNQLPTITQLSFGSLENKIININDIIIYVDPLDGTDCYTHKQYDSVCVLVGVTYKGKPMIGIVSKPFYNNEITFAIENYISSISLQPLNDKIIFVCSKKNDIQHLIKSFPDPYEVKYKGGSGAKMMAIIHQEADIYYHPLIQSCTWDTLAAQVILEAQGGIVCDIYGNPLCYPSSKKESMRHKKGVLCLSPRAKKYLPYMLSISKTILL
What is the function of this protein?
Catalyzes the hydrolysis of the 1-position phosphate from inositol 1,4-bisphosphate (PubMed:25372691).  Is also able to convert 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP but with less efficiency (PubMed:25372691).
What are the official names of this protein?
Inositol polyphosphate 1-phosphatase, EhIPPase, 3'(2'),5'-bisphosphate nucleotidase.
What is the protein family that this protein belongs to?
Belongs to the inositol monophosphatase superfamily.
Protein: SCX13_RHOJU
Sequence: KEGYPVDWGNCKYECMSDAYCKDLCVDRKAKSGYCYKLNWSCYCEGLPDDSPIKTNGHCRPGGRRK
What is the function of this protein?
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking neuronal transmission.
What are the official names of this protein?
Putative alpha-neurotoxin RjAa13.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL17_XYLF2
Sequence: MRHQKSGRKFNRTDAHRGAMFSNMIASLFKYQLIKTTLPKAKELRRFAEPLITLAKVDSVANRRLAFARLRNKEAVGILFSNLGPRYITRPGGYIRLLKCGFRHGDNAPMAYVEMLERPIIAEEVT
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: RS14_VIBC1
Sequence: MAKNSMKAREAKRAKLVAKFAEKRAALKAIISDVNASEEDRWNAVLTLQSLPRDSSASRQRNRCNQTGRPHGYLRKFGLSRIKVREACMKGEIPGLRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: LECG1_BUNMU
Sequence: MGHFTFTGLCLLAMFLSLRGAECYTCPIDWLPKNGLCYKVFSKHKTWFDAEKYCRKFKPGCHLASLHSNADAVEFSEYISDYLTGRGHVWIGLRDTKKKYIWEWTDRSRTDFLPWRKNQPDHFNNNEFCVEIVNFTGYLQWNDDNCAALRPFLCQCKY
What is the function of this protein?
Recombinant C-type lectin BML-1 is able to agglutinate erythrocytes.  May be a calcium-dependent lectin.
What are the official names of this protein?
C-type lectin BML-1, CTL.
What is the protein family that this protein belongs to?
Belongs to the true venom lectin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TUSA_ECO57
Sequence: MTDLFSSPDHTLDALGLRCPEPVMMVRKTVRNMQPGETLLIIADDPATTRDIPGFCTFMEHELVAKETDGLPYRYLIRKGG
What is the function of this protein?
Sulfur carrier protein involved in sulfur trafficking in the cell.  Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA.  Interacts with IscS and stimulates its cysteine desulfurase activity.  Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation.  Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.
What are the official names of this protein?
Sulfur carrier protein TusA, Sulfur mediator TusA, Sulfur transfer protein TusA, tRNA 2-thiouridine synthesizing protein A.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: US23_HCMVM
Sequence: MWRTRWEDGAPTFTRNDEFLYCHTRYETFLRVMGDFQGIFECQYSADVLRDWVRNHVDQVLSLGIPHNWFLQVRPGSTMPELRDQLLDDVICCPERLIVLGKCVIMVDDHYEETELVLCMGGGTRLYIYEPSQEILLLCARHLDELARYGMMYTEAVYRQPQTPFATRVPHDVVAMLLRHGHDTDALAACVGEHHGRDVNFHTPGRHAKTLKLLTSFGCLTDCWPFEVAPAARLAECEMYVTLQLRCRWYLLGAVGSYRAGGFFDTSFLIIFDRFCRFYVVIVKSHLDRSPPLQRLAGEIYRLADSLEELFRAGLMKVYVRRRYEHGLRRAARLERNGGCVHMGEAARLHFTMFDSGVDRDYARQFRWLCRGDRFRAEMLNNWDGWDAFTIWQARVVRGDFAERRRPRSLGDGEEEDEGNDGRAMPVVRRRPPPMPRDDDEDNHVVPDNQNLEVIHDALADDEEQGEDDDDSGAEPMEPEENNVVPNVDRRGGEDAVAARMAAGHESDDDEWEDLGFDLEEDTVFDLKDVDEWFEQRRLAEKERWHLGQRIVNAYRTEAEVSEAEVEARRINLNTDLSPEWVKSFDFREHFV
What are the official names of this protein?
Protein US23.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae US22 family.
What are the subcellular locations of this protein?
Virion tegument.
Protein: LOLD_GEOMG
Sequence: MSSLLEVMDLTKGYGSGETRVDVLKGINLTVAEGETIALVGASGTGKSTLLHIMGTLDRPTSGSVRFGGEDVFRLGDAALASFRNHSIGFVFQFHHLLPEFTALENVMMPLLIAGVKRSDAAAPARELLGEVGLAHRLTHKPGELSGGEQQRVAIARALVLSPKLLLADEPTGNLDMKTSDEVHETLERVHRKRGVTLVIVTHNEKLASYMGRTVRLVDGRVVAD
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LCNDL_LACLA
Sequence: MFDKKLLESSELYDKRYRNFSTLIILPLFILLVGGVIFTFFAHKELTVISTGSIEPTKIVAKIQSTNANPIIENNLKEGKVVKENSLLLKYNGTPEQTQLSELLTQKKQVLDKKAQLDLLQKSLTNEKNEFPTTDSFGYEKSFENYESQVKSLEATIQKSNQAVEDQNKSTESQKQAIQNQVATLQQAIQNYSEIENAVSSGGGVSQDNPYLSQYNSYQAQQATLEADLKNQKNPDETAKQATKSQEESLKSQFLSGLASSKDSLKSQIQSFNVQESSLTGSNAYDNSQSSQILTLKTQALSASNKEMTDLNSTLTDLETKISLQKQDDQYSQVFAEQTGVLHVLPDILGMKKIPIGTPIAEIYPLLKAETQVNLTSYIPSTQISGMKVGQKVRFTVQQNLPKPEILTGIIKQIDSAPTAFKEGNAYKVSATTAINAKDLPNIRYGLQGKTVTIIGKKTYFNYFLDKIMGRTS
What is the function of this protein?
Involved in the secretion of a lactococcin.
What are the official names of this protein?
Lactococcin A secretion protein LcnD-like.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: RBE42_LITRU
Sequence: AGLLDILGL
What is the function of this protein?
Shows neither neuropeptide activity nor antibiotic activity.
What are the official names of this protein?
Rubellidin-4.2/4.3.
What are the subcellular locations of this protein?
Secreted.
Protein: RSGA_AYWBP
Sequence: MEKALVLRFLAGVYYIKDLETQIILEAKKRGKLKTLVIKTTQKENSSASDFIIKVGDIVLYELSCDTYLIQSILPRKNELKRPNVANIDQVLLVFSLVKPNFQFLLLDKFLLILEQQKLDVVLVFSKIDLLEPENFKTMQQQLSYYQKFQHFYYINSKQKIGIDALKHIFANQITVLAGQTGVGKSTLLKVLIPDAQLKTQEISESLGRGKHTTKNAQLYDFNGGFIVDTPGFSKLDLTTFSPRTLKNFYPDFLEHVCDCFFGESCFHLQEEKCGVKKALENGQILPSRYQNYVIFCEEIKNQPKY
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLUB_HAEIN
Sequence: MKPSQKQTQRQPHFSKDSAKKRDFSAKNDRRSVSRTARIETANTKKSAVNSDNKFLSKPKAKPVVRASNQPKAEGEKLQKVLARAGQGSRREIETMIAAGRVSVEGKIATLGDRIDVHSGVKVRIDGQIINLSHTQKEICRVLMYYKPEGELCTRSDPEGRATVFDRLPRLTGSRWIAVGRLDINTSGLLLFTTDGELANRLMHPSREVEREYSVRVFGQVDDAMLARLRKGVQLEDGLANFKEIKFTGGVGINQWYDVTLMEGRNREVRRLWESQGIQVSRLIRIRYGNIKLMKGLPRGGWEEMDLENVNYLRELVGLPAETETKLDVKQASRRPKSGQIRKAVKRYSEMNKRYKK
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA.
What are the official names of this protein?
Ribosomal large subunit pseudouridine synthase B, 23S rRNA pseudouridine(2605) synthase, rRNA pseudouridylate synthase B, rRNA-uridine isomerase B.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RsuA family.
Protein: PYRD_LEPCP
Sequence: MALVPYPLTRPFLFGMDPEAAHELTLGSIARFQNTPLQCLWSQSRIADPVTVAGLRFPNRIGLAAGLDKNGRCIDGLGAMGFGFIEVGTVTPLGQPGNPKPRMFRLPEKNALINRLGFNNEGLASFLANVQRATSFRRNGGLLGLNIGKNAVTPIENAADDYLIALAGVYPHADYVTVNISSPNTKNLRALQSDAALDALLGALQTRRLALATEHGRSVPMFVKIAPDLDEAQVRVIAATLRHNGIDGVIATNTTLARDAVAGLAHADEAGGLSGAPVLAASNRVIAQLRAELGGAYPIIGVGGVLSGADARSKRAAGADLVQVYTGLIYRGPALVPECARALRG
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: NPPNK_METMP
Sequence: MDMLEMALNIAKDIEKSVKPLIGWEKSNEVVKIGADGTPTKRIDLIAENVAINSIEKVCSAILISEEIGFKRIGKNKPEYVIVLDPVDGTYNSLKDIPFYSAAVAIGRIDKFADNLEELINNLKMKDLEVGVVRNIATGDTYYAEKGKGAHFLRKGEKKSISISNSSNLKDSSIGLFAHDISIDTLKFIKDRRFRRIRLFGSIALEMCYVAKGALDAFINVNETTRLCDIAAGYVIIKEAGGIVTDKNGQEVNLDLDVNSKVSVICSNEMLHKKLVGIFGNRWRIKPTNFGIISRIDNEESIEVADNVIKYLDSKGIKYELDSSTYNALKNRLTKKCDIISNIEEISHMISIGGDGTVLRASKMIEGNEIPMVCINMGTVGFLTEFNKDEIFSAIDSIICGSYKVEKRTKLMGFAKLSDGKQHILNDSLNEVVITTKNPAKMMHFEVYIDGSLVEDVRADGIIVSTPNGSTAYSLSSGGPIIEPTVEGFVIVPICPFKLSSRPLVVNANSEIKIKLLKKSTYVVIDGNTEFEAKKGDEIILRKSESNAYFVKGDNFYNKLKKLSLM
What is the function of this protein?
Involved in the regulation of the intracellular balance between NAD(H) and NADP(H), and is a key enzyme in the biosynthesis of NADP.  Catalyzes the phosphorylation and dephosphorylation of NAD and NADP, respectively.  Although it shows conflicting dual activities and is able to supply NADP, it seems that its physiological role is to prevent excess accumulation of NADP.
What are the official names of this protein?
Bifunctional NADP phosphatase/NAD kinase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIM_LARHH
Sequence: MSDLLPLPPAAIRLPDLVRQHPPLVHCLTNQVVSQFTANVLLAAGAAPAMVIAREEAGDFARMASAVLVNVGTLTPVQADAMRVAVAAALEAGTPWTLDPVAVGALAFRTQFCRELLSQRPTAIRGNPAEILALAGEASRGRGVDSLDDSTVALAAARRLADATGAVVAVTGATDFITDGERVIALAGGHPLLQQVTGTGCSLSALVAAMTAMTDDPLSGAAVACALMKLAGERAADKAAGPGSFAVHLLDEIAALTPADLAQRWPA
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: SYS_SHIF8
Sequence: MLDPNLLRNEPDAVAEKLARRGFKLDVDKLGALEERRKVLQVKTENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGEELDAAKAELDALQAEIRDIALTIPNLPADEVPVGKDENDNVEVSRWGTPREFDFEVRDHVTLGEMHSGLDFAAAVKLTGSRFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNQDTLYGTGQLPKFAGDLFHTRPLEEEADTSNYALIPTAEVPLTNLVRGEIIDEDDLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLGLPYRKIILCTGDMGFGACKTYDLEVWIPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSGLAVGRTLVAVMENYQQADGRIEVPEVLRPYMNGLEYIG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.