PharMolix/UniProtQA huggingface dataset:
Protein: PPH6R_CAEEL
Sequence: MFWAKEEEENSLMRLLKTDNFTLEDVLLNEFVVQESRYGKAELVQYITSRENMKALLELSLNPKINTDLPMKQQYRLSFIASEILTIRGTDVFQKQIVTTEETRKCLVDFLNDKTPLNHLVAGFFAKIMECLLSRHFDLFQTFSLLQETKFFDKCLRNINLGAIECLLENLVRIPTTSEGTRIVKEWMISENLFEKIVDRMRESETDDEKECLAEVYCEILRELRDKLYIMESKVDELHAKSMDETLIAKIADNLIVEEGCPAEELVKKSALISASAKILEAFIKTNFVSNAPAQQLEEIERNLIEERHYSYGLMRPCMDNDPYEHSYQPDPERIVEGILANRLPNILQTVLRDIEANGSVWQPLLRLIIELCNTNCMSTHEKIAVAFRSLPFINLIKAAKMLPRASVLHCLLVKVVILLLHSSFPCDELSPAAEYLLTEGGLIQNIYDTATSPNPGSSVACSGLRSFNQNLGDAINRAKKAGIPNQKLLAILSADNTWTELEDIIHLYNLKHRPQMQHDFNDSSVVSSIRNDSHGFNDSEEWTDASTKFAEMDATSSAKQAFSGFSSPFEPNMQRFSDFEGQFDDTPDEDEFRKLCSERANSSSCAGISFETSPIKWPGEAEKTSEKASEPPSVVASTYPQQTNGNQAFLEQEEGDGEWVWPTVPPLGETEVVTQTGHRPENNWVDETAPDFSHLDMAPPKEDDMWADFSSFPTISPTAAANSASSSSSDAWPGSDIHLQGEASDWPLNNSHESKASDPVMVGLAASISHPGDSSEA
What is the function of this protein?
Regulatory subunit of protein phosphatase 6 (PP6) (Probable).  In complex with pph-6, promotes actomyosin contractility during cytokinesis by regulating the organization of cortical non-muscle myosin II nmy-2 and thus contributing to correct spindle positioning (PubMed:20040490).  Also required for the proper generation of pulling forces on spindle poles during anaphase by regulating the cortical localization of gpr-1, gpr-2 and lin-5 (PubMed:20040490).  Negatively regulates kinase air-1 localization at the cell cortex (PubMed:27335426).
What are the official names of this protein?
Serine/threonine-protein phosphatase 6 regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the SAPS family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle pole. Note=In embryos, localizes mainly to the cytoplasm and to a lesser extent with microtubule asters.
Protein: RSD_ECO45
Sequence: MLNQLDNLTERVRGSNKLVDRWLHVRKHLLVAYYNLVGIKPGKESYMRLNEKALDDFCQSLVDYLSAGHFSIYERILHKLEGNGQLARAAKIWPQLEANTQQIMDDYDSSLETAIDHDNYLEFQQVLSDIGEALEARFVLEDKLILLVLDAARVKYPA
What is the function of this protein?
Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA.  May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.
What are the official names of this protein?
Regulator of sigma D.
What is the protein family that this protein belongs to?
Belongs to the Rsd/AlgQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHKR_MYCTU
Sequence: MGGLRFGFVDALVHSRLPPTLPARSSMAAATVMGADSYWVGDHLNALVPRSIATSEYLGIAAKFVPKIDANYEPWTMLGNLAFGLPSRLRLGVCVTDAGRRNPAVTAQAAATLHLLTRGRAILGIGVGEREGNEPYGVEWTKPVARFEEALATIRALWNSNGELISRESPYFPLHNALFDLPPYRGKWPEIWVAAHGPRMLRATGRYADAWIPIVVVRPSDYSRALEAVRSAASDAGRDPMSITPAAVRGIITGRNRDDVEEALESVVVKMTALGVPGEAWARHGVEHPMGADFSGVQDIIPQTMDKQTVLSYAAKVPAALMKEVVFSGTPDEVIDQVAEWRDHGLRYVVLINGSLVNPSLRKTVTAVLPHAKVLRGLKKL
What is the function of this protein?
Catalyzes the reduction of the keto moiety of phthiodiolone dimycocerosates (DIM B) and glycosylated phenolphthiodiolone dimycocerosates to form the intermediate compounds phthiotriol and glycosylated phenolphthiotriol dimycocerosates during phthiocerol dimycocerosates (DIM A) and glycosylated phenolphthiocerol dimycocerosates (PGL) biosynthesis.
What are the official names of this protein?
Phthiodiolone/phenolphthiodiolone dimycocerosates ketoreductase.
What is the protein family that this protein belongs to?
Belongs to the mer family. Phthiodiolone/phenolphthiodiolone dimycocerosates ketoreductase subfamily.
Protein: RSMH_SHISS
Sequence: MMENYKHTTVLLDEAVNGLNIRPDGIYIDGTFGRGGHSRLILSQLGEEGRLLAIDRDPQAIAVAKTIDDPRFSIIHGPFSALGEYVAERDLIGKIDGILLDLGVSSPQLDDAERGFSFMRDGPLDMRMDPTRGQSAAEWLQTAEEADIAWVLKTYGEERFAKRIARAIVERNREQPMTRTKELAEVVAVATPVKDKFKHPATRTFQAVRIWVNSELEEIEQALKSSLNVLAPGGRLSIISFHSLEDRIVKRFMRENSRGPQVPAGLPMTEEQLKKLGGRQLRALGKLMPGEEEVAENPRARSSVLRIAERTNA
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GTR14_HUMAN
Sequence: MEFHNGGHVSGIGGFLVSLTSRMKPHTLAVTPALIFAITVATIGSFQFGYNTGVINAPETIIKEFINKTLTDKANAPPSEVLLTNLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVLLGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDVSQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQQPIYATISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKNHYNGMSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAYYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQAHGADRSGKDGVMGMNSIEPAKETTTNV
What is the function of this protein?
Hexose transporter that can mediate the transport of glucose and dehydroascorbate across the cell membrane.
What are the official names of this protein?
Solute carrier family 2, facilitated glucose transporter member 14, Glucose transporter type 14, GLUT-14.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MYO1_PICST
Sequence: MAIVKRGGRTKNKTQQQAPAKSGIKKAEFDLHKSKEVGVSDLTLLSKITDEAINDNLHKRFMNGTIYTYIGHVLISVNPFQDLGIYGPETLSKYRGRNRLEVPPHVFAIAESMYYNLKSYNENQCVIISGESGAGKTEAAKQIMQYIANVSVDSGNAEISKIKDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIQFSESNHQPIAAHITNYLLEKQRVVSQITNERNFHIFYQFTKHCPTQYQQQFGIQGPETYVYTSSAKCINVDGIDDSKDLDETLSAMKIIGLTELEQNNIFRMIASILWIGNVSFVEDESGNAAIRDDSVTQFVAYLLEVNPEILKKAIVERVIETTHGMRRGSTYHVPLNIVQATSVRDALAKGIYNNLFEWIVERVNVSLKGASQSSKTIGILDIYGFEIFEHNSFEQICINYVNEKLQQIFIQLTLKAEQDEYVKEQIKWTPIDYFNNKVVCDLIEATRPQPGLFAALNDSIKTAHADSDAADQVFAQRLSMVGASNRHFEDRKGKFIIKHYAGDVTYEVAGMTDKNKDALLRDLVELLSTSANPFVNQVLFPPSLLASITDSKKRPETASDKIKRSANDLVGTLSKCQPSYIRTIKPNQTKRPKEYENQQVLHQIKYLGLKENVRIRRAGFAFRTTFEKFVQRFYLLSPATGYAGDYIWRGDDISAVKEILKSCFIPATEYQLGTTKVFIKTPETLFGLEDMRDKYWHNMAARIQRAWRRYVKRKEDAARTIQSAWRIKKHGNQFEQLRDYGNGLVQGRKERRRMSMLGSRAFMGDYLGCSDTSGYGRFIVTQTGINEKVVFSGRGEILLSKFGRSSKRLPRIFVVTRTTIFIIAEVLIEKRLQLQSEFKIPISGLNYVALSHLQDNWVALSLHSPTPSTPDVFISLDFKTEFVTHLKKINPGLTINIGTTVQYQKKPGKFHTVKFISGNSSDVPEYGDVYKSGTVTVKPGLPSSSRNPKRPRGKSGKVDYSKYYNRGVKKSFPVPSARPTAASQPSYKSPVEQSYQPQVLAYQTPRPEEAKPVQRKAPPPAPVVQNQPQRQPQAIEPVRPVKKTAPSPPVRKTAPPPPPPPPALSAPAKPKFPTYKAMYDYDGSVAGSIPLVKDVVYYVESINGKWGLVKTLDESKEGWSPIDYLSQCEPPSSLFGAANPPSRPVAPSQPKVQSRESTVASAAVSSSTPASTVSNGSLSNGLAEALRAKKTEETTLAGSLADALKKRQGATRDDSDDEDDDDDDW
What is the function of this protein?
Type-I myosin implicated in the organization of the actin cytoskeleton.  Required for proper actin cytoskeleton polarization.  At the cell cortex, assembles in patch-like structures together with proteins from the actin-polymerizing machinery and promotes actin assembly.  Functions as actin nucleation-promoting factor (NPF) for the Arp2/3 complex (By similarity).
What are the official names of this protein?
Myosin-1, Class I unconventional myosin, Type I myosin.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, actin patch.
Protein: TRUA_HALSA
Sequence: MPRRAFRVAYDGRPYHGFQRQPDVSTVAGELFGALRRLDVFDGAKPPGYAAAGRTDAGVSARAQTVAFDAPAWLTPDAFTGALPDPIQVWAHADAPPEFHATHDAVARTYVYYWYAPDSRATDDRAAGALDRLTGTHDFHNLTPNTTNTVRELDATLDRDGAFRVITVRAGGFCRELVRRVVSLVQLVTETGDTDRIDTVLGDEPVAGPDGVPPADPHPLVLHAVAYDGLSFTVDEDAAERARTTFRAARADHHERARVAGHLASI
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: NDK_CAMLR
Sequence: MEKTLSIIKPDAVKKGVIGQILTRFESNGLRIAATKKIQLSEKEAQEFYAVHKDRPFFKDLVEFMISGPVVVSVLEGKNAVLKNRELMGATNPKEAAAGTIRADFADSIDANAVHGSDSLENAKIEIEFFFSKTEIL
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACKA_STACT
Sequence: MSNLVLAINAGSSSLKFQLIEIPEEKLVSKGLIERIGLKGSKITVEYDGRKFTDEKEINDHVQAVNIMLDNLIDLGIIRDINDIDGTGHRVVHGGELFPESALVTNNVEKQIESLTELAPLHNPANLMGIRAFRKLLPGIPHVAVFDTSFHQTMPEQAYLYSLPFHYYKDYGIRKYGFHGTSHKYVSQRAAEILGKPIEELRIISCHIGNGASIAAIDGGESVDTSMGFTPLAGVTMGTRSGDIDPALIPYIMEKTGKSAEAVLDILNKESGLLGISGTSSDLRDLEQDAEEGKTRAQLALDVFASRIHKYIGSYAAKMHGVDVVIFTAGVGENSDEVRARVLEGLEFMGVYWDPKKNSQLHGTEGFINYPHSPVKVIVIPTNEEVMIARDAVKFGSL
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPX_STRA3
Sequence: MLYQQIASNKRKTVVLLIVFFCLLAAIGAAVGYLVLGSYQFGLVLALIIGVIYAVSMIFQSTNVVMSMNNAREVTEDEAPNYFHIVEDMAMVAQIPMPRVFIVEDDSLNAFATGSKPENAAVAATTGLLAVMNREELEGVIGHEVSHIRNYDIRISTIAVALASAVTLISSIGSRMLFYGGGRRRDDDREDGGNILVLIFSILSLILAPLAASLVQLAISRQREYLADASSVELTRNPQGMISALEKLDRSEPMGHPVDDASAALYINDPTKKEGLKSLFYTHPPIADRIERLRHM
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GATZ_SALDC
Sequence: MKEIISRHKAGEQIGICSVCSAHPLVIESALRFDLNSGNKVLIEATSNQVNQFGGYTGMKPADFRDFVYGIAQEVGFPRERLILGGDHLGPNCWQNEPADTAMEKSVELIKAYVAAGFSKIHLDASMSCADDPTPLDPMVVAKRAALLCQAAETTATDEQKRHLTYVIGTEVPVPGGEASAINAVHVTREQDAARTLQTHQAAFRALGLDEALNRVIAIVVQPGVEFDHTQIIHYQPQAAKALSNWIKETPMVYEAHSTDYQTRQAYRALVRDHYAILKVGPALTFALREAIFALAQMENELISPEQRSRVLEVIDEVMLNEPGYWKKYYRPTWSQAMVDIHFSLSDRIRYYWPHPRIRQSVEKLIANLNNVTLPLGLISQFMPVQFERLSEGVLTPTPHNLIIDKIQDVLRAYRFGCTPDVA
What is the function of this protein?
Component of the tagatose-1,6-bisphosphate aldolase GatYZ that is required for full activity and stability of the Y subunit.  Could have a chaperone-like function for the proper and stable folding of GatY.  When expressed alone, GatZ does not show any aldolase activity.  Is involved in the catabolism of galactitol.
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit GatZ.
What is the protein family that this protein belongs to?
Belongs to the GatZ/KbaZ family. GatZ subfamily.
Protein: PUR5_SHEB9
Sequence: MSTPTPLSYKDAGVDIDAGNALVSNIKAAVKRTRRPEVMGNLGGFGALCEIPTKYKQPVLVSGTDGVGTKLRLAIDYKKHDTVGIDLVAMCVNDLIVQGAEPLFFLDYYATGKLDVETATSVVNGIGEGCFQSGCALIGGETAEMPGMYEGEDYDLAGFCVGVVEKADIIDGSKVAAGDALIALASSGPHSNGYSLVRKVLEVSQADPQQDLNGKPLIEHLLEPTKIYVKSLLKLIAASDVHAMAHITGGGFWENIPRVLPDNLKAVIQGDSWQWPAVFSWLMENGNIAEYEMYRTFNCGVGMLVALPADKVDAALALLAAEGEQAWLIGAIADREGNEEQVEIL
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGA_RHILO
Sequence: MTIEIPAHMHPSRSFQGLILTLHNYWAAYGCVILQPYDMEVGAGTFHPATTLRALGPKRWNAAYVQPSRRPKDGRYGENPNRLQHYYQYQVILKPNPPNLQELYLGSLAAIGVDPLLHDIRFVEDDWESPTLGAWGLGWECWCDGMEVSQFTYFQQVCGIECAPVAGELTYGLERLAMYVQGVDNVYDLNFNGREGADKVTYGDVFLQAEQEYSRHNFEYADTAMLLRHFEDAEAECKALLDAGAPASNDNLPMHKMVFPAYDQCIKASHVFNLLDARGVISVTERQSYILRVRNLAKACGEAFLKTQAGGLAA
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSTT_SALPA
Sequence: MATQRASGLLQRLAQGSLVKQILVGLVLGILLAWISKPAAEAVGLLGTLFVGALKAVAPVLVLMLVMASIANHQHGQKTNIRPILFLYLLGTFSAALAAVVFSFAFPSTLHLSSSAQDIVPPSGIVEVLRGLLMSMVSNPIDALLNANYIGILVWAVGLGFALRHGNETTKNLVNDMSNAVTFMVKLVIRFAPVGIFGLVSSTLATTGFSTLWGYAHLLVVLIGCMLLVALVVNPLLVFWKIRRNPYPLVFACLRESGVYAFFTRSSAANIPVNMALCEKLNLDRDTYSVSIPLGATINMAGAAITITVLTLAAVHTLGVPVDLPTALLLSVVASLCACGASGVAGGSLLLIPLACNMFGIPNDIAMQVVAVGFIIGVLQDSCETALNSSTDVLFTAAACQAEDERLANNALRS
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y135_DEHMB
Sequence: MPRPYKCRRISEIPKVAYYKPAGIPLSMLEENQLSTEEAEALRLKDLLGLEQAQAALQMNISRPTFQRMLYSARYKVADALLNGKALRIEGGVFEIDARPCCQRQTPSCQPDPPKQT
What are the official names of this protein?
UPF0251 protein DehaBAV1_0135.
What is the protein family that this protein belongs to?
Belongs to the UPF0251 family.
Protein: IPT_AGRRH
Sequence: MLLYLIYGPTCSGKTDIAIQIAQKTGWPVVALDRVQCCPQIATGSGRPLPSELQSTRRIYLDSRRLTKGIIDAEGAHRRLILEVDWQESEEGLILEGGSVSLLNCMAKSPYWKSGFQWHVKRLRLGDSDAFLARAKQRVTEMFAIREDRPSLLEELAELWNYPATRPILEDIDGYRCAIRFARKHDLAINQLPDIDAERQQDLIEAIAKEYLEHAIMQERDFPQWPEDGARQPVGPATLMRIQ
What is the function of this protein?
Transfers dimethylallyl groups to AMP as part of the biosynthesis of cytokinin phytohormones.
What are the official names of this protein?
Adenylate dimethylallyltransferase, Dimethylallyl transferase, Isopentenyl transferase, Trans-zeatin producing protein.
What is the protein family that this protein belongs to?
Belongs to the isopentenyl transferase family.
Protein: NU2C_TRIV2
Sequence: MDFANLAAQLNAGTILPEGIVIVTLMGVLIVDLILGRTSSRWIGYLAIAGLLAAIVALYFQWDATNPISFTGGFIGDDLSIIFRGIIALSAVVTILMSIRYVEQSGTALAEFIAILLTATLGGMFVSGASELVMIFISLETLSISSYLLTGYTKRDPRSNEAALKYLLIGASSTAVFLYGVSLLYGLSGGQTELSAIANGIITANVGQSLGAVIALVFVIAGIGFKISAAPFHQWTPDVYEGAPTPVIAFLSVGSKAAGFALAIRLLTTVFPFVAEEWKFVFTALAVLSMILGNVVALAQTSMKRMLAYSSIAQAGFVMIGLIAGTDAGYASMIFYLLVYLFMNLCGFTCIILFSLRTGTDQIAEYSGLYQKDPLLTLGLSISLLSLGGIPPLAGFFGKIYLFWAGWQAGLYWLVLLGLVTSVVSIYYYIRVVKMMVVKEPQEMSDVVKNYPEIRWNLPGFRPLQVGLVLTLIATSVAGILSNPLFTLANNSVANTAILQTTKVVSTQVSAIPAEKSEGL
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2, NAD(P)H dehydrogenase subunit 2, NADH-plastoquinone oxidoreductase subunit 2, NDH-1, subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: NHAP2_PSEP1
Sequence: MDASTINSLFLIGALLVGASILVSSLSSRLGIPILVIILAVGMLAGVDGGGIIFNNYPTAYLVGNLALAVILLDGGLRTRVASFRVALWPALSLATVGVMITTALTGLIAAWLFNLSLIQGLLIGAIVGSTDAAAVFSLLGGKGLNERVSATLEIESGSNDPMAVFLTVTLIDMIASGETGLHWSLLGHLLREFGIGTLLGLGGGWLMLQLVNRINLAGGLYPILVVAGGLVMFSLTNALHGSGFLAVYLCGLVLGNKPIRSRHGILHMLDGMAWLAQIGMFLVLGLLVTPHDLLPIALPALGLALWMILVARPLSVVAALLPFKAFHGREKGFISWVGLRGAVPIILAVFPLMAGLPDAQLFFNLAFFIVLVSLLVQGTSLPWVAKLLKVTVPPDPAPISRSALEVHITSEWEMFVYRLGAEKWCIGAALRELKMPEGTRIAALFRGEQLLHPSGSTVLEVGDMLCVIGHEHNLPALGKLFSQAPQRGLDLRFFGDFVLEGDAELGAVAALYGLKLDGLDAKMPLAQFIRQKVGGAPVVGDQVEWHGTIWTVATMDGNKIQKVGVRFPEGTRPGPGLFL
What is the function of this protein?
K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.
What are the official names of this protein?
K(+)/H(+) antiporter NhaP2, Potassium/proton antiporter NhaP2.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NADC_METJA
Sequence: MLKDYALKILKKSLEYDVGFGDITTNSIIPEGVKAKGVIKAKEKCIVCGIDFIVAFFEEYGIKCKKLFNDGEEAYGNILEFEGDARTILMLERTALNLLMHLSGIATMTNRIVKKAKSVNKNVRVACTRKTLPLLSPLQKYAVYIGGGDTHRFRLDDCVLIKDNHIAIVGVKEAIRRAKENVSFTKKIEVEVSNLKELREALEERADIIMLDNFKPEEIEEALKIIDEFERKTNFKPIIEVSGGIKEDNILEYAKYNVDVISMGALTHSVKSVDMSLDIVRYQ
What is the function of this protein?
Involved in the catabolism of quinolinic acid (QA).
What are the official names of this protein?
Probable nicotinate-nucleotide pyrophosphorylase [carboxylating], Quinolinate phosphoribosyltransferase [decarboxylating], QAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NadC/ModD family.
Protein: CRCB1_THEFY
Sequence: MTALLTAVGAAFGALLRYCLNCAAAARGTTGFPWGTWCVNTLGCLLAGALAALPLPAAVAALAGPGLCGGLTTYSTFSYETVRLLAERKWTHALGNIGANLAAGVGAAVLGMAAVGWFLR
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 1.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UREE_BURMS
Sequence: MRTIDKRIAPNVRLAATLVARAPALTLAYDARCKSRLAATLDTGEDVALVLPRGTVLRDGDVLVADDGALVRVAAAHEAVLLVRAPDALTLTRAAYHLGNRHTPVEVGAGCLKLEYDPALADMLTRLGATVERASAPFQPEAGAYGGGHRHGHDATFAEDYALAQQVFDEHHGHSHSHSHSHSHDHDHQHGPSCSHGHHHGHR
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EF2K_MOUSE
Sequence: MADEDLIFCLEGVDGGRCSRAGHNADSDTDSDDDEGYFICPITDDHMSNQNVSSKVQSYYSNLTKTECGSTGSPASSFHFKEAWKHAIEKAKHMPDPWAEFHLEDIATEHATRHRYNAVTGEWLKDEVLIKMASQPFGRGAMRECFRTKKLSNFLHAQQWKGASNYVAKRYIEPVDRSVYFEDVQLQMEAKLWGEDYNRHKPPKQVDIMQMCIIELKDRPGQPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTEKGTDFGDGNLGVRGMALFFYSHACNRICQSMGLTPFDLSPREQDAVNQSTRLLQSAKTILRGTEEKCGSPRIRTLSSSRPPLLLRLSENSGDENMSDVTFDSLPSSPSSATPHSQKLDHLHWPVFGDLDNMGPRDHDRMDNHRDSENSGDSGYPSEKRSDLDDPEPREHGHSNGNRRHESDEDSLGSSGRVCVETWNLLNPSRLHLPRPSAVALEVQRLNALDLGRKIGKSVLGKVHLAMVRYHEGGRFCEKDEEWDRESAIFHLEHAADLGELEAIVGLGLMYSQLPHHILADVSLKETEENKTKGFDYLLKAAEAGDRHSMILVARAFDTGLNLSPDRCQDWSEALHWYNTALETTDCDEGGEYDGIQDEPQYALLAREAEMLLTGGFGLDKNPQRSGDLYTQAAEAAMEAMKGRLANQYYEKAEEAWAQMEE
What is the function of this protein?
Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation.  Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive.  In turn, the rate of protein synthesis is reduced.
What are the official names of this protein?
Eukaryotic elongation factor 2 kinase, eEF-2 kinase, eEF-2K, Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Alpha-type protein kinase family.
Protein: PMG1_ARATH
Sequence: MATSSAWKLDDHPKLPKGKTIAVIVLDGWGESAPDQYNCIHNAPTPAMDSLKHGAPDTWTLIKAHGTAVGLPSEDDMGNSEVGHNALGAGRIFAQGAKLCDQALASGKIFEGEGFKYVSESFETNTLHLVGLLSDGGVHSRLDQLQLLIKGSAERGAKRIRVHILTDGRDVLDGSSVGFVETLEADLVALRENGVDAQIASGGGRMYVTLDRYENDWEVVKRGWDAQVLGEAPHKFKNAVEAVKTLRKEPGANDQYLPPFVIVDESGKAVGPIVDGDAVVTFNFRADRMVMHAKALEYEDFDKFDRVRYPKIRYAGMLQYDGELKLPSRYLVSPPEIDRTSGEYLTHNGVSTFACSETVKFGHVTFFWNGNRSGYFNEKLEEYVEIPSDSGISFNVQPKMKALEIGEKARDAILSGKFDQVRVNIPNGDMVGHTGDIEATVVACEAADLAVKMIFDAIEQVKGIYVVTADHGNAEDMVKRDKSGKPALDKEGKLQILTSHTLKPVPIAIGGPGLAQGVRFRKDLETPGLANVAATVMNLHGFVAPSDYEPTLIEVVE
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate (2-PGA) and 3-phosphoglycerate (3-PGA) (PubMed:21813794).  Required for guard cell function (e. g.  blue light-, abscisic acid- (ABA), and low CO(2)-regulated stomatal movements) and fertility (e. g.  pollen grains production) (PubMed:21813794).
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase 1, BPG-independent PGAM 1, Phosphoglyceromutase 1, PGAM-I 1.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_PSYCK
Sequence: MASFSTNEFKSGLKVMLDGNPCAILENEFVKPGKGQAFNRVKLRNLRSGKVLEQTFKSGDSLEAADVMDTEMNYLYNDGEFWHFMHPESFEQIQADKTAMSDSIKWLKENSNALCTITLFNGAPLSVTPPNFVELQITETDPGVRGDTSGGGGKPATLETGAVVRVPLFVQQGEVVRVDTRTGDYQTRVS
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HV692_HUMAN
Sequence: MDCTWRILLLVAAATGTHAEVQLVQSGAEVKKPGATVKISCKVSGYTFTDYYMHWVQQAPGKGLEWMGLVDPEDGETIYAEKFQGRVTITADTSTDTAYMELSSLRSEDTAVYYCAT
What is the function of this protein?
V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170).
What are the official names of this protein?
Immunoglobulin heavy variable 1-69-2.
What are the subcellular locations of this protein?
Secreted. Cell membrane.