PharMolix/UniProtQA huggingface dataset:
Protein: HES2_RAT
Sequence: MRLPRGVGDAAELRKSLKPLLEKRRRARINESLSQLKGLVLPLLGAETSRYSKLEKADILEMTVRFLREQPASVCSTEAPGSLDSYLEGYRACLARLARVLPACSVLEPAVSARLLEHLRQRTVSGGPPSLTPASASAPAPSPPVPPPSSLGLWRPW
What is the function of this protein?
Transcriptional repressor of genes that require a bHLH protein for their transcription.
What are the official names of this protein?
Transcription factor HES-2, Hairy and enhancer of split 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: DPO3_LISW6
Sequence: MTAKEEEKQERFQLLMTQIGLQDVTTYEEFTKDAKIEKLIADKKNKTWQFHLHVPQIFPAPLFHMMDVGMKRAFSQIAETEMQIVPENQTINETLIQEYWNLIVEPIGKQSPMIGKLLMEQKPTFKEPHFIEVAVHNDMEEATIQQRFQAKIIENYGKAGFPRLAMKMHMLDQSESDEYKAFAQAKQEEDQKKAAEAVQVMQKRQAEGQNGNSSAAPLSGPFQIGYKIKDDEEIKRLGDVYDEERRITVQGLIFATEIRELRSGRSLLQFKITDYTSSMIIKMFSRDNEDAAMFQNLKKGMWVKVRGSVQNDTFVRDLIMMAQDINEIAGVKRLDTAEEKRAELHLHSPMSQMDATSSVDSLFKQAADWGHKAIAITDHSVAQSFPEAYGAGQKYGLKVIFGIEANLIDDGVPIAYNDQHIGLQDATYCVFDVETTGLSAVYDTIIELAGVKMKNGEIIDKFEAFIDPGHPLSATTINLTGITDDMVKGSDPIDVVLKRFKEWSGDDILVAHNASFDMGFINTAYEKVGLEKADNAVVDTLELARFLYPHFKNHRLNTLTKKFNIILEQHHRAVFDAEATAYLAWKLIKDAKEMHDINFHDSLNDYMGEGDAYKRARPFHATIYAQTDVGLKNLFKLITMSNINYFYRVPRIPRSQLKKLREGLIVGTACSQGELFEAMMQKGMQAAEKVVEFYDFIEIQPKPVYAPLIERELVRDEKALEEILKNIVRVGEKAGKPVVATGNVHYKDPVDKIYRKILIHSQGGANPLNRAELPDVHFRSTDEMLKEFAFLGEEKAKEVVVTNSNLVVDWMEELKPIKDELYTPKIDGAEDEVRNMSYDMAHQLYGENLPEIVEARLEKELKSIIGHGFAVIYLISHKLVKKSLVDGYLVGSRGSVGSSFVATMTEITEVNPLPPHYLCPNCKDSEFFDDGSVGSGFDLPDKECPHCGTAYQKEGQDIPFETFLGFKGDKVPDIDLNFSGDYQPVAHAYTKEIFGEDYVFRAGTIGTVAEKTAFGYVRNYERDMNMTIRGAEIDRLVAGCTGVKRTTGQHPGGIIVIPDYMDVYDFTPVQFPADATDSEWKTTHFDFHSIHDNVLKLDILGHDDPTAIRMLQDLSGIDPKTIPTDDPDVMKLFGSTESLGVKPADIDSKTGTLGIPEFGTRFVRQMLEQTKPTTFSELVQISGLSHGTDVWLGNAEELIKNKTCELPDVIGCRDDIMVFLIYQGLESSLAFKIMESVRKGKGLTEEMEEAMMANKVPLWYIESCKKIKYMFPKAHAAAYVLMAVRIAYFKVHYPLYFYATYFTVRADDFDLTSMVNGKEAVKATMKEVNDKGMEASTKEKNLLTVLEIANEMLARGFHFQKVDLYKSSADEFIIDGDSLIPPFNAIPSLGTNVAKQIVAARENGEFLSKEDLQQRGKVSKTIIQYMDDQGCLEGLPDQNQLSLF
What is the function of this protein?
Required for replicative DNA synthesis.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.
What are the official names of this protein?
DNA polymerase III PolC-type, PolIII.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. PolC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WHIA_PAEAT
Sequence: MALTASVKDELSRLDIKKSSVRKAEVSAMLRFAGGLHIISGRIVIEAEVDLASTARRLRAAIAEVYGHQSEIIVVSGGGLRRGSRYVVRVVRDGEALARQTGLLDGRGRPVRGLPSAVVNGSAADAEAVWRGAFLAHGSLTEPGRSSSLEVTCPGPESALALVGAARRLGIQAKAREVRGVDRVVIRDGDTIATLLTRMGAHDALMVWEERRMRKEVRATANRLANFDDANLRRSAQAAVAAGARVDRALEILGDDVPDHLKYAGELRVAHKQASLDELGRLADPPMTKDAIAGRIRRLLAMADKRALDLGIPGTEANVTPEMMDE
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: MURA_SHEB9
Sequence: MDKLTIQASPPLAGDVIISGAKNAALPILMAGVLAETDFVVSNVPNLRDVTTSCKLLRCLGAEVTELGDGQIRISTTNLNEFCAPYDLVKTMRASILILGPLLARYGTADVSLPGGCAIGARPVNLHLHGLEMMGAKIEVKEGYIKARVDGRLKGAHIFMDMVSVGATENLLMAAALADGETVIENAAREPEVIDLANCLIAMGAKITGVGSATLRIQGVERLQGCNYRVMPDRIETGSFLVAAAVTRGRIRCLKADPASLESVIAKLEDAGAKITTGEDWIELDMQGKRPKAVNIKTAPYPGFPTDMQAQFCVLNALAQGTATITETIFENRFMHVPELIRMGATMELEGNTCIIQGIESLSGAQVMATDLRASASLVIAGLVADGKTIVDRIYHLDRGYEHIENKFQGLGAQVVRTQ
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPD_PAEAT
Sequence: MTSPASAPAASNTWPGLISALINGDDLAVGNTEWAMNTIMAGEATPAQIAGFLVALRAKGETVEELAGLVEAMVQHANPIDISGEKLDIVGTGGDRLNTVNISTMAALVAAGAGAKVVKHGNRAASSASGSADVLEALGVRLDLSIEQVARNAEEAGITFCFAQVFHPSFRHTAVPRRELAVPTAFNFLGPMTNPAHVQASAVGVANARMAPLVAGVLARRGSRGLVFRGDDGLDELTPTGPSTVWEFRNGTVKEQVFTPADLGIRPSTVADLRGGDAAANAAVVREILDGKTGPVRDAVLLNAAAGLVSIDLHAEGSLEQRMRTAFARAAESVDSGKAAEVLAKWTALSQS
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: YBEY_JANSC
Sequence: MEIDILIDAPHWDALDLCGLAQSACVATLTDLSLDPDDFALSILACDDARIATLNTQFRGKPTPTNVLSWPSEDRAPETPGAMPHLSDLAAELGDLALAFETCAREAADGGKPLPDHISHLIVHGLLHCLGFDHETDADADLMERLETRILARLGVPDPY
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SENP3_MOUSE
Sequence: MKETIQGTGSWGPEPPGPGTTYSNPRRERLRWPLPPKPRLKSGGGFGPDPGSGTTVPTRRLPAPRPSFDASASEEEEEEEEEDEEEVAAWRLPPRWGQLGASQRSRALRPSHRKTCSQRRRRAMRAFQMLLYSKSTSLTFHWKLWGRHRGRRRNLAHPKNHLSPQEGGATPQVPSPCCRFDSPRGLPPPRLGLLGALMAEDGMRGSPPVPSGPPMEEDGLRWTPKSPLDPDSGLLSCTLPNGFGGLSGPEGERSLAPPDASILISNVCSIGDHVAQELFQSSDLGIAEEADRTGEKAGQHSPLREEHVTCVQSILDEFLQTYGSLIPLSTDEVVEKLEDIFQQEFSTPSRKSLVLQLIQSYQRMPGNAMVRGFRVSYKRHVLTMDDLGTLYGQNWLNDQVMNMYGDLVMDTVPEKVHFFNSFFYDKLRTKGYDGVKRWTKNVDIFNKELLLIPIHLEVHWSLISVDVRRRTITYFDSQRTLNRRCPKHIAKYLQAEAVKKDRLDFHQGWKGYFKMNVARQNNDSDCGAFVLQYCKHLALSQPFSFTQQDMPKLRRQIYKELCHCKLTV
What is the function of this protein?
Protease that releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjugates (PubMed:11029585).  Deconjugates SUMO2 from MEF2D, which increases its transcriptional activation capability (By similarity).  Deconjugates SUMO2 and SUMO3 from CDCA8 (By similarity).  Redox sensor that, when redistributed into nucleoplasm, can act as an effector to enhance HIF1A transcriptional activity by desumoylating EP300 (By similarity).  Required for rRNA processing through deconjugation of SUMO2 and SUMO3 from nucleophosmin, NPM1 (By similarity).  Plays a role in the regulation of sumoylation status of ZNF148 (By similarity).  Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes (PubMed:22872859).  Deconjugates SUMO2 from KAT5 (By similarity).
What are the official names of this protein?
Sentrin-specific protease 3, SUMO-1-specific protease 3, Sentrin/SUMO-specific protease SENP3, Smt3-specific isopeptidase 1, Smt3ip1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C48 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Cytoplasm. Note=Redistributes between the nucleolus and the nucleoplasm in response to mild oxidative stress (By similarity). Mainly found in the nucleoplasm, with low levels detected in the cytoplasmic and chromatin fractions (PubMed:22872859).
Protein: BMT_AMMMJ
Sequence: MAEMKTSPSQDEEAGVVAMQLATSTVLPMILKSAIELDLLNTIAKAGPGNYLSPSDLASKLLLSNPDAPVMLARILRVLATYKVLGCKRGEVEWLYCWTPVCKYLSNNEDGASIAPILLVHQDKVTIKSWYHLTDAVRDGGTAFNKAHDMSIFEYASQDPQFNKAFNRSMRGHSTITMKKILETYKGFEGLKSIVDVGGGTGATLNMIISKYPTIKGINFDLPHVVGDAPSLPGVEHVGGNMFASVPKGDAIFLKWIFHSWGDEECLKILKKCHQALGDNKKVIVAEFILPEDPGGSDSATKSAVHLDAIMLAYVPGGKERTEKEFESLAKRAGFKSFTKVCCAFNTWIMEFSK
What are the official names of this protein?
Bergaptol O-methyltransferase, BMT.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. COMT subfamily.
Protein: 5NTD_HUMAN
Sequence: MCPRAARAPATLLLALGAVLWPAAGAWELTILHTNDVHSRLEQTSEDSSKCVNASRCMGGVARLFTKVQQIRRAEPNVLLLDAGDQYQGTIWFTVYKGAEVAHFMNALRYDAMALGNHEFDNGVEGLIEPLLKEAKFPILSANIKAKGPLASQISGLYLPYKVLPVGDEVVGIVGYTSKETPFLSNPGTNLVFEDEITALQPEVDKLKTLNVNKIIALGHSGFEMDKLIAQKVRGVDVVVGGHSNTFLYTGNPPSKEVPAGKYPFIVTSDDGRKVPVVQAYAFGKYLGYLKIEFDERGNVISSHGNPILLNSSIPEDPSIKADINKWRIKLDNYSTQELGKTIVYLDGSSQSCRFRECNMGNLICDAMINNNLRHTDEMFWNHVSMCILNGGGIRSPIDERNNGTITWENLAAVLPFGGTFDLVQLKGSTLKKAFEHSVHRYGQSTGEFLQVGGIHVVYDLSRKPGDRVVKLDVLCTKCRVPSYDPLKMDEVYKVILPNFLANGGDGFQMIKDELLRHDSGDQDINVVSTYISKMKVIYPAVEGRIKFSTGSHCHGSFSLIFLSLWAVIFVLYQ
What is the function of this protein?
Catalyzes the hydrolysis of nucleotide monophosphates, releasing inorganic phosphate and the corresponding nucleoside, with AMP being the preferred substrate (PubMed:21933152, PubMed:34403084, PubMed:24887587, PubMed:22997138, PubMed:23142347).  Shows a preference for ribonucleotide monophosphates over their equivalent deoxyribose forms (PubMed:34403084).  Other substrates include IMP, UMP, GMP, CMP, dAMP, dCMP, dTMP, NAD and NMN (PubMed:21933152, PubMed:34403084, PubMed:24887587, PubMed:22997138, PubMed:23142347).
What are the official names of this protein?
5'-nucleotidase, 5'-NT, 5'-deoxynucleotidase, Ecto-5'-nucleotidase, IMP-specific 5'-nucleotidase, Thymidylate 5'-phosphatase.
What is the protein family that this protein belongs to?
Belongs to the 5'-nucleotidase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: FEM1C_XENLA
Sequence: MDLKTAVFNAARDGKLRLLSKLLENKAKDDVVLLMSEKTNGATPLLMAARYGHLDMVDYLLDQCSASVEIGGSVNFDGETIEGAPPLWAASAAGHLKVVRSLLVHGASVNNTTLTNSTPLRAACFDGHLEIVKYLVEHKADLEVANRHGHTCLMISCYKGHKEIAQFLLEKGADVNRKSVKGNTALHDCAESGSLEIMQMLLKYGARMEKDGYGMTPLLSASVTGHTNIVDFLTQNPQTSKNERINALELLGATFVDKKRDLLGALKYWKRAMDMRHSDRTNIVSKPEPQTLIMAYDYAREVNTAEELDNLIADPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFKRCINLWKYALDMQQNNLDPLSPMTASSLLSFAELFSFMLQDRAKGLLGTTVTFDDLMGILCKSVMEIDRAVKQTAPPPDQVQLNKALSIILHLICLLEKVPCSPDQDHFKKQNIYRFLKLHPKGKNNFSPLHLAVDKNTTCVGRYPVCKFPSFQVTAILLECGADVNVRDAEQNSPLHVAALNNHPDIMNLLVKSGAHFDSTNSHNQTACDLLDEKEMAKNLIQPINHTTLQCLAARVIVKHNIQYKQEIPEKLESFVLLHR
What is the function of this protein?
Substrate-recognition component of a Cul2-RING (CRL2) E3 ubiquitin-protein ligase complex of the DesCEND (destruction via C-end degrons) pathway, which recognizes a C-degron located at the extreme C terminus of target proteins, leading to their ubiquitination and degradation.  The C-degron recognized by the DesCEND pathway is usually a motif of less than ten residues and can be present in full-length proteins, truncated proteins or proteolytically cleaved forms.  The CRL2(FEM1C) complex specifically recognizes proteins with an arginine at the C-terminus: recognizes and binds proteins ending with -Lys/Arg-Xaa-Arg and -Lys/Arg-Xaa-Xaa-Arg C-degrons, leading to their ubiquitination and degradation.
What are the official names of this protein?
Protein fem-1 homolog C, FEM1c, FEM1-gamma.
What is the protein family that this protein belongs to?
Belongs to the fem-1 family.
Protein: PLSX_CHLAB
Sequence: MNVQIGIDLMGGDHSPLVIWEVLIDVLNSRASNSHISFTAFASHEVKEQILSHSTYKGYPEVIASESFITMEDSPLSAIRKKSSSMALGLDYLKEDKIDALISTGNTAALITLSRTKIPMFPTVRRPALLVRVPTMRGCAVILDVGANVSVNPEEMLGFARMGLAYKQCLGDTEHPTVGLLNIGSEERKGTEAHRLTFRLLRETFQHAFLGNIESGDVFSGSVDVVVSDGFTGNIFLKTAEGVFDFLSHILGDKLESDVKRQLDYTIYPGSMVCGLSKLVIKCHGKACGRSLFNGISGSIDLVRARVCERILSSLS
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: MURB_STRPJ
Sequence: MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRFELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGANLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEIETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEYPSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQSVIEKVKEHSGITLEREVRILGESLSVAKMYAGGFTPCKR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAJ_SYNS3
Sequence: MKKFLTTAPVVAAIWFTLTAGILIEWNRFFPDLLFHPMG
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: ACEK_BORBR
Sequence: MIYSGDVQRIEPAPVAGPAPLDVAHLILAGFDRHYALFRYSAQRAKSLFESGDWHGMQRLSRERIEYYDMRVRECATQLDSALRGSDARTADGSRANGSAALSEAQTAFWQAVKQEFVGLLADHRQPECAETFFNSVSCRILHRDYFHNDFLFVRPAIATDYLDSRIPSYRVYYPVAEGLHKSLIRMVADFGLAVPYADLPRDARLLARAAVRQLRGQLPRHAGPRLASDCQIQVLGSLFFRNTGAYIVGRLINQGTVYPFAVALRRNPAGQVCLDALLLGADDLSTLFSFTRAYFLVDMETPAAVVNFLASLLPRKPKAELYTMLGLQKQGKTLFYRDFLHHLTHSRDAFDIAPGIRGMVMCVFTLPSYPYVFKLIKDRIDKDGMDHATVRRKYQMVKLHDRVGRMADTWEYSQVALPRSRFAPRLLEELRRLVPSLIEENGDTVVIRHVYIERRMMPLNLYLRHASDPLLEVAVREYGDAIRQLATANIFPGDMLYKNFGVTRLGRVVFYDYDEIQRMTEMNFRAIPPAPNEEAELSSEPWYAVGPNDVFPEEFGRFLLGDPRVRQAFLRHHADLLAPQWWQACRARVAQGRIEEFFPYDTDRRLHPQAAPPPRTAA
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_CAMJJ
Sequence: MKQTKYIFVTGGVLSSLGKGIAAASIATLLKNSGLKVSILKADPYINVDPGTMSPFEHGEVFVTDDGAETDLDLGHYERFLDESLSQDNNFTTGRVYQSVIEKERRGEYLGKTIQVIPHIVGEIKDRIKKAGEGKDILIVEIGGTVGDIEGLPFLEAIRALRLEVGKNNAMNIHLTLVPFIKAAGELKTKPTQHSVGELRRIGISPDMIICRSEKALDRDLKDKIAISCGVEKNCVIESVDAASIYQIPLNFLKQDILSPIAEILDLKNLKPNMENWDSLVKRVIAPSNEVKIAFVGKYVDLKESYKSLTEAIIHAGAALDTKVELKWVDSEKLENMESSEVFKDVSGILVAGGFGYRGVEGKIKAIQYARENKIPFLGICLGMQLALVEFARNVLKLKDANSSEFNEKCQNPVVYLIDEFMDTNGEKQIRTAKTPLGGTMRLGAYKCDIKEKSLLAKVYNEVKSVKERHRHRYEANPKYRADFEKHGLIVSGESKGLIEAVELNCHPFFLAVQFHPEFTSRLEHVNPVICSFIKAAINYEDN
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: DCD_NEIG1
Sequence: MSIKSDKWIRRMSEEFGMIDPFEPNQIKEADGQRIISYGTSSYGYDIRCANEFKIFTNINSTIVDPKNFDPKNFVTVEDDCCIIPPNSFALARTVEYFRIPRNVLTVCLGKSTYARCGIIVNVTPFEPEWEGYVTLEFSNTTPLPAKIYAGEGVAQVLFFESDEVCETSYKDRNGKYMGQTGVTLPKA
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: BIN3_MOUSE
Sequence: MSWIPFKIGQPKKQIVSKTVERDFEREYGKLQQLEEQTKRLQKDMKKSTDADLAMSKSAVKISQDLLSNPLCEQDQDFLHMVTALDTAMKRMDAFNQEKVNQIQKTVIEPLKKFSSIFPSLNMAVKRREQALQDYGRLQAKVEKYEEKEKTGPVLAKLHQAREELRPVREDFEAKNKQLLDEMPRFYGSRLDYFQPSFESLIRAQVIYYSEMHKIFGDLTQQLDQPGHSDEQRERENETKLSELRALSIVADD
What is the function of this protein?
Involved in cytokinesis and septation where it has a role in the localization of F-actin.
What are the official names of this protein?
Bridging integrator 3.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: AGT23_ARATH
Sequence: MRKLTAVNSLLKRNNYLLPRHGSSQTAAQRTSSVRETETETKLPKMPPFNYSPPPYDGPSTAEIIAKRREFLSPALFHFYNTPLNIVEAKMQYVFDENGRRYLDAFGGIATVSCGHCHPEVVNSVVKQLKLINHSTILYLNHTISDFAEALVSTLPGDLKVVFFTNSGTEANELAMMMARLYTGCNDIVSLRNSYHGNAAATMGATAQSNWKFNVVQSGVHHAINPDPYRGIFGSDGEKYASDVHDLIQFGTSGQVAGFIGESIQGVGGIVELAPGYLPAAYDIVRKAGGVCIADEVQSGFARTGTHFWGFQSHGVIPDIVTMAKGIGNGIPLGAVVTTPEIAGVLSRRSYFNTFGGNPMCTAAGHAVLRVLHEEKLQENANLVGSHLKRRLTLLKNKYELIGDVRGRGLMLGVEFVKDRDLKTPAKAETLHLMDQMKEMGVLVGKGGFYGNVFRITPPLCFTLSDADFLVDVMDHAMSKM
What are the official names of this protein?
Alanine--glyoxylate aminotransferase 2 homolog 3, mitochondrial, Beta-alanine-pyruvate aminotransferase 3.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: HIS7_CAUVC
Sequence: MARTAEVVRETKETQIRVWIDLDGTGVSTISTGIGFYDHMLESFARHGGFDLKVETKGDLHIDMHHTVEDTGIVLGQAIHKALDGFKGIRRFGSAYIPMDETLTRCAIDLSNRPYLIWKVEFKRPKVGEMDTELFKEFHHAFAMNSGACIHLETLYGDNTHHVAESGFKALARALRQAVEIDPKTGGQAPSTKGVL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GGR_METM7
Sequence: MRALNDSYDVVVVGAGPAGSMASYNASKNGAKTLLIEKSQEIGTPVRCAEAVPRIEEFGINPDPSFIKSYIKGGYLIAPNGKKVVVKGGKTDGYVVERKVFDKYLAIRSGQAGTQIAVKSRVTGIEKTDDGYNVFVNYLGDEYVVKSKIVIAADGVESNIAEYAGLKSKKNPKEICSCAEYEMTNVQLLDNEMMEFYFGDICPKGYIWLFPKGDTVNVGIGVIDSKKRAIDYLDEFLSNPLVEGRLDNAVPVEFKVGGDPVGGPIEKTVDDNIIVVGDAAGHVSPLTGGGIGLSMDCGLMAGEVAAQSIKAENYSEEFLSLYEKRWKEKYYKPLMKDLKYKNILQKLSDDELNAIADSIPENLEEVDVGKLAVKIVAKAPSLLRYFKELL
What is the function of this protein?
Is involved in the reduction of 2,3-digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids.  Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains.
What are the official names of this protein?
Digeranylgeranylglycerophospholipid reductase, DGGGPL reductase, 2,3-bis-O-geranylgeranylglyceryl phosphate reductase, Geranylgeranyl reductase, GGR.
What is the protein family that this protein belongs to?
Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily.
Protein: CYSJ_SODGM
Sequence: MTKQAPPTTVLPLSEEQLDRLQTATGDLSPLQLAWISGYFWGRVAEGKPAVPPPSQSAAAAAPITLISASQTGNARRLAEQLRDDLIAARLDVVLINAGDYKFKQIAQEKLLLIITSTQGEGDPPEEAVALYKYLFSKKAPALPSTQFAVFGLGDSSYEHFAKTGKDFDSRLAELGAQRLHDRVDADVDYQAQAETWRAAIVEQLKSRVAVASPAQQQLAASGNVNEVDSSPYTKEAPLTAHLALSQKITSRQSLKDVRHLEIDLTDSGLRYQPGDALGVWYENDPALICELLALLWLKGKGDEPVPVAGQTLPLAEALQKHYELTQNTPAIVAGYAAFARDEALLAVVADKAQLQQFALATPIVDMVRRAPIELSAEQLLSLLRPLTPRLYSIASSQAEVGEEVHITVGVVRYEIDGRPRTGGASGYLADRLGEDDELRVFIEHNDNFRLPGDPNTPVIMIGPGTGIAPFRAFLQQREADGAPGQNWLFFGNPHFTDDFLYQVEWQRYVKERLLTKISLAWSRDQAEKIYVQDRVREQGAEVWRWIQQGAHIYVCGDANRMARDVEQALVAVVAEYGCMDPEQADEYLSELRIERRYQRDVY
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.  The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
What are the official names of this protein?
Sulfite reductase [NADPH] flavoprotein alpha-component, SiR-FP.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Protein: ASD_METBU
Sequence: MLAKDSLSWVVTVVTLTGIFLTAAVLTGIDLVWYLFYMSLFLTFFVIWFFRDPDRTTRICDHCMFSAADGKVMDVSGRRVCVFMNVHNVHVNRTPISGVVKSITHKKGGYLPAFHKDSERNERTVTVIKSSHGEVNVTQIAGVMVRRIVSYINVGDELVNGEKIGMIRFGSRVDVTIPDDFDIACKVGDRVYAGETVIAKKKNFKVRK
What is the function of this protein?
Catalyzes the formation of archaetidylethanolamine (PtdEtn) from archaetidylserine (PtdSer).
What are the official names of this protein?
Putative archaetidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SRR_DICDI
Sequence: MEPMATVTLKDIKEAHKRIEKYIHKTPVLTNSTINELAGKELYFKCENLQKTGSFKMRGACNAIFSLDEEELSKGVVTHSSGNHGQALSYASKVRCVKCYVVVPEDAPSVKLNAICGYGATVTKCKATLEARESNTKQLIEQHSCKLIHPFDNLQVIAGQGTASLELMEQVENLDAIITPVGGGGLLSGTCITAKSLNPNIKVFAAEPLGADDTYRSLLSGEIQKHTPGKPNTIADGLLTTVGSLTFPIIKENCDGVILVTEDEIKYAMKLVWERMKIIIEPSSATTLAAILKQEFKDKKDIKKVGIIISGGNVDLSSISKILN
What is the function of this protein?
May catalyze the synthesis of D-serine from L-serine.  May have serine dehydratase activity (By similarity).
What are the official names of this protein?
Probable serine racemase, D-serine ammonia-lyase, D-serine dehydratase, L-serine ammonia-lyase, L-serine dehydratase.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family.
Protein: IPYR5_ARATH
Sequence: MNGEEVKTSQPQKKLQNPTPRLNERILSSLSKRSVAAHPWHDLEIGPGAPVIFNVVIEISKGSKVKYELDKKTGLIKVDRILYSSVVYPHNYGFVPRTLCEDNDPIDVLVIMQEPVLPGCFLRARAIGLMPMIDQGEKDDKIIAVCVDDPEYKHITNINELPPHRLSEIRRFFEDYKKNENKEVAVNDFLQPGPAIEAIQYSMDLYAEYILHTLRR
What are the official names of this protein?
Soluble inorganic pyrophosphatase 5, Pyrophosphate phospho-hydrolase 5, PPase 5.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCB5R_DICDI
Sequence: MQISDFILVIIGSVALAAGVKYVFTLTSGSNKDKKGGEAEKGKQVEKALDPQEYRKFQLKEKFIVNHNTRIFRFALPNEDDILGLPIGQHISLRAVVGGKEVYRPYTPISSDEERGYFDLLIKVYEKGAMSGYVDNMFIGDSIEVKGPKGKFNYQPNMRKSIGMLAGGTGITPMLQVIKAILKNPSDKTEISLVFGNITEEDILLKKELDELAEKHPQFKVYYVLNNPPKGWTQGVGFVSKEIIESRLPSPSDQTMVIMCGPPMMNKAMTGHLETIGFNESNIFTF
What is the function of this protein?
Electron donor reductase for cytochrome b5.  The cytochrome b5/NADH cytochrome b5 reductase electron transfer system supports the catalytic activity of several sterol biosynthetic enzymes (By similarity).
What are the official names of this protein?
NADH-cytochrome b5 reductase 1.
What is the protein family that this protein belongs to?
Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion outer membrane; Single-pass membrane protein.