PharMolix/UniProtQA huggingface dataset:
Protein: CRYAB_HUMAN
Sequence: MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFPTSTSLSPFYLRPPSFLRAPSWFDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKPAVTAAPKK
What is the function of this protein?
May contribute to the transparency and refractive index of the lens.  Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.  In lens epithelial cells, stabilizes the ATP6V1A protein, preventing its degradation by the proteasome (By similarity).
What are the official names of this protein?
Alpha-crystallin B chain, Alpha(B)-crystallin, Heat shock protein beta-5, HspB5, Renal carcinoma antigen NY-REN-27, Rosenthal fiber component.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Secreted. Lysosome. Note=Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles (PubMed:19464326). Localizes at the Z- bands and the intercalated disk in cardiomyocytes (PubMed:28493373). Can be secreted; the secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum- Golgi intermediate compartment) followed by vesicle entry and secretion (PubMed:32272059).
Protein: KHSE_CLONN
Sequence: MIKVKVPGTTANMGPGFDSFGMALDIYNEITVEEIESGFEMLQEGELSEIPLAENLIYTTFLNTLNKHNYKYKGFRINLSKCDVPMSRGLGSSATCIVGGIFAANSIMGNVMSFDEIIKEAVSIEGHPDNVVPAIVGGMTVSIMDKDNVIYSNVTVPDRLRAFVMIPNYKLGTEEARGVLPDSYTREECVFNISRAAMLVNVMNNGEIEKLRLCMQDKIHQKYRGALIRNIDDIFKKAYEFGSLAEFISGSGSTLIAFIDKDNNEFYDRMKNFLDTLEDEWTVHLLKPNFTGAEIIKNR
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AUNB_ASPNA
Sequence: TADNMLNALFYFLLRNPQCLKRLEEEVSCVGATVNELSDDRLAKLPYLNACINETFRIAPAFNGGILQRVSCGATVDGVYVPPGVAVSVDHYTLGHDPQYWVKPDVFNPERWIDPDCKDNFKASRPFLIGARQCPGRQMAYQMFRVCVAKLVYLYTFEL
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of aurasperone B, a dimeric gamma-naphthopyrone (PubMed:31067027).  The first step in the biosynthesis of aurasperone B is the production of gamma-naphthopyrone precursor YWA1 by the non-reducing polyketide synthase albA, via condensation of one acetyl-CoA starter unit with 6 malonyl-CoA units (PubMed:31067027).  YWA1 is then methylated by aunE at position C-6 to yield foncesin which is further methylated at position C-8 by aunD to produce fonsecin B (Probable).  A key enzyme in the biosynthetic pathway is the cytochrome P450 monooxygenase aunB which catalyzes the oxidative dimerization of fonsecin B to aurasperone B (PubMed:31067027).  AunB also catalyzes the oxidative dimerization of rubrofusarin B into aurasperone A (PubMed:31067027).
What are the official names of this protein?
Cytochrome P450 monooxygenase aunB, Aurasperone B biosynthesis cluster protein B.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: ENGB_HALLT
Sequence: MFEDRPDRDAEVVLVGRSNVGKSTLMRELTGHDFSTGGKPGVTRQPNHFDWASESFMFTDLPGFGFMSGVEEEHREAIKTNIVRYLEENADSILAGVVVMDGKAAVDIIDRHAERGNIPHDVEMFGFLEDVGVEPIVAVNKTDKIDDLDERLDEICDRLGLYPPWQQWSDQIAPICAKRGDIEALEECLRTRFHEHNRDDLLKFVS
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: KEL3_YEAST
Sequence: MAKKNKKDKEAKKARAELKNQKNQKKQEKKFQKNKNKSLNGEEDDESDQDLDEILSSFSKKQIELEHVDITSVEKPSCRTHPLMFANPQHNKHELFIFGGEFTDPETKLTHFYNDLYSYSIKNNSWKKYVSQNAPLPRSSAAVAVHPSGIALLHGGEFSSPKQSKFYHYSDTWLFDCVERKFTKLEFGGRDSSPSARSGHRIIAWKNYFILFGGFRDLGNGQTSYLNDLWCFDISTYKWTKLETNSKPDARSGHCFIPTDNSAILMGGYCKIIAKNNKNLMKGKILNDAWKLNLTPDPKKWQWEKLKNFKNQPSPRVGYSFNLWKQNKSVAFGGVYDLQETEESLESVFYNDLYMFHLELNKWSKLRIKPQRQTNSKNSPATSKRKSNKDQEKELQDLLNSILAKSNLNDDDDDNDDNSTTGPNSIDDDEDNEDDSDLDNQEDITISNQLPHPRFNAATCVVGDSLFIYSGVWELGEKDYPINSFYSIDLNKLDGVKVYWEDLSAIEEAKRLGDRDSDEDEFEYEDDEEDEDDGEEEQDAGPLEGDEDEESESDDDKQAQMEIPDERSWLPHPKPFETLRAFYLREGANFLTWSISNNRNLKGKQLKTKSFELCEDRWWERRDQVTLEEERLEDTGGIIERDTTTKPSKRR
What are the official names of this protein?
Kelch repeat-containing protein 3.
Protein: MDH_XANOM
Sequence: MKAPVRVAVTGAAGQIGYALLFRIASGEMLGKDQPVILQLLELSNEKAQAALKGVMMELEDCAFPLLAGMVGTDDAEVAFKDIDVALLVGARPRGPGMERKDLLLENAKIFTAQGAALNKVAKRDVKVLVVGNPANTNAYIAMKSAPDLNPKNFTAMLRLDHNRALSQLALKLGKPVGGIEKLVVWGNHSPTMYPDYRFATSDGASIGDAINDQEWNASTFIPTVGKRGAAIIEARGLSSAASAANAAIDHVRDWVLGSNGKWVTMGVPSDGSYGISEGVIFGFPVTTENGQYSLVKDLPIDDFSQKYIDKTLAELEEERSGVSHLLG
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: OMPX_ECO57
Sequence: MKKIACLSALAAVLAFTAGTSVAATSTVTGGYAQSDAQGQMNKMGGFNLKYRYEEDNSPLGVIGSFTYTEKSRTASSGDYNKNQYYGITAGPAYRINDWASIYGVVGVGYGKFQTTEYPTYKHDTSDYGFSYGAGLQFNPMENVALDFSYEQSRIRSVDVGTWIAGVGYRF
What are the official names of this protein?
Outer membrane protein X.
What is the protein family that this protein belongs to?
Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpX family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: RBL_NYPFR
Sequence: AGFKAGVKDYKLTYYTPDYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIETVVGEENQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPSYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCTEAIYKAQTETGEIKGHYLNATAGTCEEMMKRAIFARELGVPIIMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHGGTVVGKLEGEREMTLGFVDLLRDDFIEKDRSRGIFFTQDWVSMPGVIPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIREASKWSPELAAACEVWKEIKFDF
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NDPA_PASMU
Sequence: MSINVNEIVLHQITKSIEGDAMKLNTMLRERLLTITPEVEQMMLQLHQAYQNKSKAYAVFNENSLFAQDLNRFLEHESEFLDFSQKATALLVNELSRYPFADEGTLVLCRYNFLATDYLFIALLDSRASMLVDEQLEIHRTKYLEISQFDIAARLNLTELSLDAKSDRYLTFVKGRVGRKIGDFFMDFLGAEEGLNPQVQNQCLLQAVSDYCAQADLSKEQSQAVKKQVFEYCKGQMNVGEEIALTELSATMPTLNEQAFASFAAEQAYGLAEHIPPVRSALKTLTKFSGSGKGITLSFDAELINQRVFWDEATDSLTIQGLPPNLRDQLQRQLKGQN
What are the official names of this protein?
Nucleoid-associated protein PM1885.
What is the protein family that this protein belongs to?
Belongs to the YejK family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RECR_SYNJA
Sequence: MYTRPLARLIEELQRLPGIGSKTAQRLALHLLNRPAGEVEALAKALLEAKQTVKHCSICFNWSAEDPCEICRSPQRDPSTWCVVADVKDLIAMERTREFKGLYHVLGGLISPMNGIGAEQLRIRELVARVAREKPQELIFALSPSVEGEVTMHVVKDYLKPVAPGLRMTRLAFGLPMGSELEYADEVTLARALEARQEF
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: NSAC_SPHXE
Sequence: MSSVSELGYLGMSVTDLDAWRAYAAEVAGMEVVDEGESDRIYLRMDLWHHRIALIKGDTDDLAYMGWRLGDPTEFESMVEKLTNAGIAVTVASDAEARERRVLGLAKLTDPGGNPTEIFYGPQVDAHKPFHPGRPMFGKFVTGSEGIGHCILRQDDVEAAAAFYRLLGLRGSVEYQLHLPNGMVAMPYFMHCNERQHSVAFGLGPMEKRINHLMFEYTELDDLGLAHDIVRERQIDVALQLGKHANDLALTFYCANPSGWLWEFGWGARKAPAQQEFYTRDIFGHGNEAQGYGMDVPL
What is the function of this protein?
Involved in the naphthalene and naphthalenesulfonate catabolic pathway.  Catalyzes the meta-cleavage of 1,2-dihydroxynaphthalene (1,2-DHN) to yield 2-hydroxychromene-2-carboxylic acid.  Can also cleave 1,2,5-trihydroxynaphthalene (1,2,5-THN), 1,2,6-trihydroxynaphthalene (1,2,6-THN), 1,2,7-trihydroxynaphthalene (1,2,7-THN), 2,3-dihydroxybiphenyl, 3,4-dihydroxybiphenyl, catechol, 3-methylcatechol and 4-methylcatechol.
What are the official names of this protein?
1,2-dihydroxynaphthalene dioxygenase, 1,2-DHN dioxygenase, DHNDO.
What is the protein family that this protein belongs to?
Belongs to the extradiol ring-cleavage dioxygenase family.
Protein: TRI5_FUSBO
Sequence: MENFPTEYFLNTSVRLLEYIRYRDSNYTREERIENLHYAYNKAAHHFAQPRQQQMLKVDPKRLQASLQTIVGMVVYSWAKVSKECMADLSIHYTYTLVLDDSSDDPHPAMLNYFDDLQAGREQAHPWWALVNEHFPNVLRHFGPFCSLNLIRSTMDFFEGCWIEQYNFGGFPGSDDYPQFLRRMNGLGHCVGASLWPKELFDERKNFLEITTAVAQMENWMVWVNDLMSFYKEFDDERDQISLVKNFVTCHEITLDEALEKLTQETLHSSKQMVAVFADKDPQVMDTIECFMHGYVTWHLCDARYRLHEIYKKVKDQDTEDAKKFCKFFEQAANVGAVAPSEWAYPQVAQLANVRAKGDVKEAQKPILSSIELVE
What is the function of this protein?
TS is a member of the terpene cyclase group of enzymes.  It catalyzes the isomerization and cyclization of farnesyl pyro-phosphate to form trichodiene, the first cyclic intermediate in the biosynthetic pathway for trichothecenes.  It serves to branch trichothecene biosynthesis from the isoprenoid pathway.
What are the official names of this protein?
Trichodiene synthase, Sesquiterpene cyclase, TS.
What is the protein family that this protein belongs to?
Belongs to the trichodiene synthase family.
Protein: SURE_FLAPJ
Sequence: MSKPLILVTNDDGISAPGIRSLIAVMQEIGTVVVVAPDSPQSAMGHAITINSTLHLNKISAENAAVTEYSCSGTPVDCVKLAVNEILKQKPDLCVSGVNHGSNSSINVIYSGTMSAAVEAGIEGIPAIGFSLLDYDWNADFETFKPYIKKIALEVLQKGLPDSVVLNVNFPKRKEEDLKGIKICRQAKAMWEEKFDKRKTPQGKDYYWLTGEFVNHDKGEDTDEWALQNGYISVVPVQFDMTAHHAIQALNNWDLNK
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SKI8_DANRE
Sequence: MSTQYSILFKQEHAHEDAIWTAAWGRSEKDGSETIVTGSLDDLVKVWKWSDEKLELQWTLEGHQLGVVSVNISQNGAIAASSSLDAHIRLWDLETGKQIKSMDAGPVDAWTVAFSPDSKYIATGSHLGKVNIFGVESGKKEHSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHGSWVLSVAFSPDDTHFVSSSSDKSIKVWDTSSRSCVNTFFDHQDQVWSVKYNPTGSKIVSAGDDRAIHIYDCPM
What are the official names of this protein?
SKI8 subunit of superkiller complex protein, WD repeat-containing protein 61.
Protein: ISPG_SALHS
Sequence: MHNQAPIQRRKSTRIYVGNVPIGDGAPIAVQSMTNTRTTDVEATVNQIKALERVGADIVRVSVPTMDAAEAFKLIKQQVNVPLVADIHFDYRIALKVAEYGVDCLRINPGNIGNEERIRMVVDCARDKNIPIRIGVNAGSLEKDLQEKYGEPTPQALLESAMRHVDHLDRLNFDQFKVSVKASDVFLAVESYRLLAKQIDQPLHLGITEAGGARSGAVKSAIGLGLLLSEGIGDTLRVSLAADPVEEIKVGFDILKSLRIRARGINFIACPTCSRQEFDVIGTVNALEQRLEDIITPMDVSIIGCVVNGPGEALVSTLGVTGGNKKSGLYEDGVRKDRLDNDDMIAQLESRIRAKASQLDEARRIDVLQVEK
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: SYA_ARCFU
Sequence: MTLDEEYLDITFLTENGFVRKRCPKCGKHFWTADPEREICGDPPCESYSFIGNPVFKKPFELDEMREYYLNFFERRGHGRIERYPVVARWRTDIYLTIASIADFQPFVTSGVAPPPANPLTISQPCIRLDDLDSVGRTGRHLTLFEMMAHHAFNYPGKEIYWKNETVAYCTELLNELGVKKEDIVYKEEPWAGGGNAGPCLEAIVGGLEVATLVFMNLEEHPEGDIEIKGARYRKMDNYIVDTGYGLERFVWASKGTPTVYDAIFPEVVDTIIDNSNVSFNREDERVRRIVAESSKLAGIMGELRGERLNQLRKSVADTVGVSVEELEGIVVPLEKVYSLADHTRCILFMLGDGLVPSNAGAGYLARLMIRRSLRLAEELELGLDLYDLVEMHKKILGFEFDVPLSTVQEILELEKERYRTTVSKGTRLVERLVERKKKLEKDDLIELYDSHGIPVELAVGIAAEKGAEVEMPKDIYAELAKRHSKAEKVQEKKITLQNEYPATEKLYYDDPTLLEFEAEVIGVEGDFVILNRSAFYPESGGQDNDVGYLIANGGKFEVVDVLEADGVVLHVVKGAKPEVGTKVKGVIDSDVRWRHMRHHSATHVLLYSLQKVLGNHVWQAGARKEFSKARLDVTHFRRPSEEEIKEIEMLANREILANKPIKWEWMDRIEAERKFGFRLYQGGVPPGRKIRVVQVGDDVQACGGTHCRSTGEIGMLKILKVESIQDGVIRFEFAAGEAAIEAVEEMERLLREASSILRVEPAKLPKTVERFFEEWKDQRKEIERLKSVIADLWADILMERAEEFDSMKVVAEVVDADMQALQKLAERLAEKGAVGCLMAKGEGKVFVVTFSGQKYDARELLREIGRVAKGSGGGRKDVAQGAVQQLLDREEMLDVIFRFLSEHEG
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Incorrectly charged aminoacyl-tRNA(Ala) is also edited in situ by the editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAT4_ORYSJ
Sequence: MAARSELLRPAFGEASPSLGRFVINPHSCSYRWWHMFLIMLVLYSAWASPFELSMEKAASIALVVTDLVVDVFFAIDIALSFFVAYRDTSTGLLITDRRKITMRYLKRPCFALDVASTIPLQIIYQLVTGKRQGLWGLLNLLRLWRLRRVSKLFARVEKDIRFNYLWTRLIKLLCVTLFALHFAACIYLWMAFNYKIKELTWIGSQIHSFEDRSVWFCYTCAVYWSITTLATVGYGDLHATNIGEMLFSIAFMLFNMGLTSYIIGNITNLVVRETSNTFKMRDMVQRVSEFGRMNRLPEAMREQMLASVQLRFRTDEQLQQEMLSELPKAVRSGVMKHMFKSAIESCYLFQGVSDSLIVQLVAEMKAEFFPPKANVILENETSTDCYIIISGEVEALTTLADGTEKHVKRIGPRGMAGEIGVMFSIPQPFTIRSRRLTQVVRISHIHLLQAVRPNTADGYIVFSNFIQYLESLKVQTKDVAFVSDHLWNGNSMVLRRATEVAVDESKEAAHKMLPCKEPKRVVIHEQLPNATSTALHPSPGKLVLLPDSMQELMKLSEKKFGKAVRGILTVEGAEVEDIEVIRDGDHLLFS
What is the function of this protein?
Probable inward-rectifying potassium channel.  Assuming opened or closed conformations in response to the voltage difference across the membrane, the channel is activated by hyperpolarization (By similarity).
What are the official names of this protein?
Potassium channel KAT4.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. Plant (TC 1.A.1.4) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SYFA_FUSNN
Sequence: MKEEILKVKEEIQTYIKESKTLQRLEEIRVNYMGKKGIFTELSKKMKDLSVEERPKIGQIINEVKEKINSLLDERNKALKEKELNERLESEIIDISLPGTKYNYGTIHPINETMELMKNIFSKMGFDIVDGPEIETVEYNFDALNIPKTHPSRDLTDTFYLNDSIVLRTQTSPVQIRYMLEHGTPFRMICPGKVYRPDYDISHTPMFHQMEGLVVGKDISFADLKGILTHFVKEVFGDRKVRFRPHFFPFTEPSAEMDVECMICHGDGCRLCKESGWIEIMGCGMVDPEVLKYVGLNPDEVNGFAFGVGIERVTMLRHGIGDLRAFFENDMRFLKQFK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_CAMJD
Sequence: MDDNKRKSLDAALKSLDKTFGKGTILRLGDKEVEQIDSIGTGSVGLDLALGIGGIPKGRIVEIYGPESSGKTTLTLHIIAECQKAGGVCAFIDAEHALDVKYAKNLGVNTDDLYVSQPDFGEQALEIVETIARSGAVDLIVVDSVAALTPKAEIEGDMGDQHVGLQARLMSQALRKLTGIVHKMNTTVIFINQIRIKIGATGYGTPETTTGGNALKFYASVRLDVRKIATLKQNEEPIGNRVKVKVVKNKVAPPFRQAEFDVMFGEGLSREGELIDYGVKLDIVDKSGAWFSYKDKKLGQGRENSKAFLKENPEIADEITKAIQNSMGIEGMISGSEDDEGEE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDH_ENT38
Sequence: MKVAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAVDLSHIPTAVKIKGFSGENARPALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKNLVQQIAETCPKACVGIITNPVNTTVAIAAEVLKKAGVYDKNKLFGVTTLDIIRSNTFVAELKGKSPSDIEVPVIGGHSGVTILPLLSQIPGVSFSEQEVADLTKRIQNAGTEVVEAKAGGGSATLSMGQAAARFGLSLVRALQGEKGVVECAYVEGDGEHARFFSQPLLLGKNGIEERQSIGKLSAFEQQAMEGMLDTLKKDITLGEEFVSK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: G6PI_CLOB8
Sequence: MNKGISLDLSKVSPYLEEAELENMESMVKAVHEDLHNKTGAGNDFLGWVDLPVNYDKEEFARIKKAAEKIKSDSDVLIVIGIGGSYLGARAAIEMLTNNFHNVLGSDKRKVPQIFFAGNNISSTYMAELLQVIEGKDVSLNVISKSGTTTEPAIAFRILKSYLEKKYGVEEARKRIYATTDKARGALKTLADSEGYETFVVPDDVGGRFTVLTAVGLLPIAAAGIDIDEMMKGAADARTAYSVPSIKENDAYKYAAARNALYNKGASIEVLVNYEPSLHYFNEWWKQLYGESEGKDHKGLFPAAVDFSTDLHSMGQYIQDGRRIMFETVVNIEKPKYEINIEEADNDLDGLNFLAGKTMDFVNKKAFEGTLLAHNDGGVPNMILNVPEISAYYFGYMVYFFEKACGISGYLLAINPFNQPGVEAYKKNMFALLGKPGYEDMKAELEKRL
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_SHIDS
Sequence: MAAVKCKPTSPGRRHVVKVVNPELHKGKPFAPLLEKNSKSGGRNNNGRITTRHIGGGHKQAYRIVDFKRNKDGIPAVVERLEYDPNRSANIALVLYKDGERRYILAPKGLKAGDQIQSGVDAAIKPGNTLPMRNIPVGSTVHNVEMKPGKGGQLARSAGTYVQIVARDGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAARWRGVRPTVRGTAMNPVDHPHGGGEGRNFGKHPVTPWGVQTKGKKTRSNKRTDKFIVRRRSK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: PP2AB_RABIT
Sequence: MDDKTFTKELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL
What is the function of this protein?
Catalytic subunit of protein phosphatase 2A (PP2A), a serine/threonine phosphatase involved in the regulation of a wide variety of enzymes, signal transduction pathways, and cellular events.  PP2A can modulate the activity of phosphorylase B kinase, casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase.
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform, PP2A-beta.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Chromosome, centromere. Cytoplasm, cytoskeleton, spindle pole. Note=In prometaphase cells, but not in anaphase cells, localizes at centromeres. During mitosis, also found at spindle poles (By similarity).
Protein: RL15_LACDA
Sequence: MKLNELHPSEGSRHARKRVGRGTSSGFGKTSGRGQKGQHARSGGNTRLGFEGGQMPLFRTMPKRGFKNINRKEYAIVNLADLNKFEEGSVVDFEALKAKGLVKKQLSGVKVLGNGDLNVKLTVKVNKVSEAAKSAIEAAGGTVEVI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: CH60_STAA3
Sequence: MVKQLKFSEDARQAMLRGVDQLANAVKVTIGPKGRNVVLDKEFTAPLITNDGVTIAKEIELEDPYENMGAKLVQEVANKTNEIAGDGTTTATVLAQAMIQEGLKNVTSGANPVGLRQGIDKAVKVAVEALHENSQKVENKNEIAQVGAISAADEEIGRYISEAMEKVGNDGVITIEESNGLNTELEVVEGMQFDRGYQSPYMVTDSDKMVAELERPYILVTDKKISSFQDILPLLEQVVQSNRPILIVADEVEGDALTNIVLNRMRGTFTAVAVKAPGFGDRRKAMLEDLAILTGAQVITDDLGLDLKDASIDMLGTASKVEVTKDNTTVVDGDGDENSIDARVSQLKSQIEETESDFDREKLQERLAKLAGGVAVIKVGAASETELKERKLRIEDALNSTRAAVEEGIVAGGGTALVNVYQKVSEIEAEGDIETGVNIVLKALTAPVRQIAENAGLEGSVIVERLKNAEPGVGFNAATNEWVNMLEEGIVDPTKVTRSALQHAASVAAMFLTTEAVVASIPEKNNDQPNMGGMPGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCDA_NATTJ
Sequence: MFKGLFKKTKYISLNPERKTELRSDQNDNKSNKPHIPDGLWEKCDSCKSIIYAEDLKKNYHICHECGHHFRIGAQERINQIIDEDTWVELDQNIISENPLEFEGYSEKVDKLQKKTELKEAILTGLGKINGQQAVIGAMDSRFLMGSMGSVVGEKVTRAIETGIDENLPVIMFTASGGARMQEGIYSLMQMAKTSAAISKLKDKGLPYIVVLTDPTTGGVTASFAMLGDIILAEPNALIGFAGKRVIEQTIKQKLPKEFQRAEFLLKHGFVDKVINRKEMRNKLSHILKLHKTKQPSRMLDGNDCSYYSSKDASKKASAKSVEEIRQQGKKLTPYDKVKLVRSKERPTSLDYIDNIFEGFIEFHGDRYFADDTSIVGGLAFLNGLPVTVIGQQKGRDLQENIYRNFGMPNPEGYRKAVRLMQQAEKFNRPIINFVDTSGAGCGKGAEERGQGEAIAQNLYTMSSLKVPIISLVIGEGGSGGALALTVADEVWMLENSVYSIVSPEGFASILWKDSSKAKEAADVMKITAQDLQELQIIDKILEEPYQDASKDGQAMSEIIKNNLLKTLDNLSKKETNDLLTKRYEKFRSIGRFIEKSNLDSSINQ
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA (By similarity).
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunits beta/alpha, ACCase subunits beta/alpha, Acetyl-CoA carboxylase carboxyltransferase subunits beta/alpha.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_THESQ
Sequence: MKMIIGRKIGMTRVFVGNDSVPVTVIKAGPCVVVQKKTVEKDGYNAVQLGFEKAKKVNKPLAGHFKKFGVEPMKILREFRVENPDEYEPGQVIKVDVFEKGEYVDVTGWTKGRGFAGAMKRWGFSGGPKSHGSKFHRELGSVGQHTEPAKIWKGKKMPGRYGNERVTVRNLQVVDIDPENDLLVVKGGVPGARGGLVLIRSAKAPKK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: THIG_XANAC
Sequence: MTNPAPSDALVIAGKHYRSRLLTGTGKFKDLDETRLATEAAAAEIVTVAIRRVNIGQDPNAPSLLDVLPPERYTLLPNTAGCYTAEDAVRTCRLARELLDGHNLTKLEVLGDEKTLYPDVVQTLKAAEQLVADGFEVMVYTSDDPILAKRLEDIGCVAVMPLAAPIGSGLGIQNKYNLLEIIENAKVPIIVDAGVGTASDAAIAMELGCDGVLMNTAIAGARDPILMASAMRKAIEAGREAFLAGRIPRKRYASASSPVDGVIG
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.