PharMolix/UniProtQA huggingface dataset:
Protein: LPXA_STRM5
Sequence: MTDNAPRIHPTAVIDPAARLADDVQVGAFTLIGADVEIGAGTVVGPHCSIHGPTRIGRDNRFVGHAAIGGEPQDKKFAGERTELVIGDRNVFREFVTVNRGTGGGGGITTIGNDNWMLAYTHVAHDCHVGNFCVFSNNTTLAGHVTVGDYVIISGFAGAHQFCRIGAHAFLGMGALTNGDVPPFTMVGTDSLGRPRGINSEGLKRRGFDAERISAIKRAYRTLYVAGLPLAEAKQQLTEQARGSDDVKAMLDFIEHAERPLLR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_BORA1
Sequence: MSRLQDFYKSKVAVDLQAKFGYKSVMEVPRITKITLNMGVSEAVADKKVIEHAVSDLTKIAGQKPVITKTRKAIAGFKIRENYPIGCMVTLRGQRMYEFLDRLVAIALPRVRDFRGISGRAFDGRGNYNIGVKEQIIFPEIEYDKIDALRGLNISITTSAKTDEEAKALLTAFSFPFRN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: RL9_LACDA
Sequence: MKVIFMQDVKGRGKLGQVKDVPNGYAQNYLIKQGLAKEANKGNLNTLKRVEANEKAEYEAQKAAAQEIKKQLEADETVVELKAKAGSDSRLFGSISSKKIIEGLDKQFGIKLDKHKLELREPIKVLGYTNVPVKLFKGVESKVRVHVTQEN
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: AP1S1_ARATH
Sequence: MIHFVLLVSRQGKVRLTKWYSPYTQKERSKVIRELSGVILNRGPKLCNFIEWRGYKVVYKRYASLYFCMCIDEADNELEVLEIIHHYVEILDRYFGSVCELDLIFNFHKAYYILDELLIAGELQESSKKTVARIISAQDQLVEVAKEEASSISNIIAQATK
What is the function of this protein?
Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting at the trans-Golgi network and early endosomes (TGN/EE).  The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (By similarity).
What are the official names of this protein?
AP-1 complex subunit sigma-1, Adaptor AP-1 19 kDa protein, Adaptor protein complex AP-1 sigma-1 subunit, Adaptor-related protein complex 1 sigma-1 subunit, Clathrin assembly protein complex 1 sigma-1 small chain, Clathrin assembly small subunit protein AP19-1, AtAP19-1, Sigma 1 subunit of AP-1 clathrin, Sigma-adaptin 1, Sigma1-adaptin.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes small subunit family.
What are the subcellular locations of this protein?
Golgi apparatus. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NEMA4_LINSA
Sequence: GCISTGSFCTLSKGCCTKNCGWNFKCNPPNQ
What is the function of this protein?
Highly potent toxin against insect sodium channel (Nav) and with less potent against some mammalian Nav (PubMed:34445875).  Potently inhibits inactivation of insect sodium channels of B. germanica (BgNav1) (EC(50)=11. 1 nM) (PubMed:34445875).  Also delays the inactivation of most mammalian Nav (hNav1. 1/SCN1A; EC(50)=92 nM, rNav1. 2/SCN2A; EC(50)=134. 2 nM, rNav1. 3/SCN3A; EC(50)=12. 9 nM, rNav1. 4/SCN4A; EC(50)=14. 6 nM, hNav1. 5/SCN5A; EC(50)=27. 8 nM, mNav1. 6/SCN8A; EC(50)=123. 6 nM, hNav1. 9/SCN9A; EC(50)=80. 5 nM) (PubMed:34445875).  1 uM is enough to completely inhibits the inactivation, resulting in sustained non-inactivating currents (By similarity).  In addition, the toxin significantly enhances the recovery from inactivation, and the open state is not required for the toxin to interact with the channel (By similarity).  In vivo, injection into brine shrimp (Artemia salina) stops movement or causes death after 24 hours (EC(50)=0. 4 uM) (PubMed:34445875).
What are the official names of this protein?
Nemertide alpha-4.
What is the protein family that this protein belongs to?
Belongs to the nemertide family.
What are the subcellular locations of this protein?
Secreted.
Protein: RSD_ECOK1
Sequence: MLNQLDNLTERVRGSNKLVDRWLHVRKHLLVAYYNLVGIKPGKESYMRLNEKALDDFCQSLVDYLSAGHFSIYERILHKLEGNGQLARAAKIWPQLEANTQQIMDDYDSSLETAIDHDNYLEFQQVLSDIGEALEARFVLEDKLILLVLDAARVKYPA
What is the function of this protein?
Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA.  May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.
What are the official names of this protein?
Regulator of sigma D.
What is the protein family that this protein belongs to?
Belongs to the Rsd/AlgQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURI_CHLTE
Sequence: MPQHKVSSDSPIGIFDSGIGGLTVVKAVQAALPSERIIYFGDTARVPYGSKSQVTIRKYAREDTELLMKHQPKLIIVACNTVSALALDVVEQTAGGIPVIGVLKAGAELAVQKTKSGRIGVIGTQATIGSNAYTCAIREEKETLEVFPKACPLFVPLAEEGFIDHPATRLVAEEYLAAFTGKEIDTLVLGCTHYPILRKIIESITGPEITIIDSAEAVASKAGELLAARGLLNQSPEKALPHLMVSDLPQKFRELYRLFMGTELPDVELVGM
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: T53I1_MOUSE
Sequence: MFQRLNKMFVGEVTTSSSQEPEFSEKEDDEWILVDFIDTCPGFSAEEEEEDEDIGEESSAEHTSVFSCLPASLECLTDTSDSCFLQFESCPMEESWFITPPPCFTAGGLTTIKVETSPMENLLIEHPSMSVYAVHNSCPGLSEASCGNDEYNSSGPRMEAQSEMGKHIHCCVAALAAQATFLEQPKSFRPSQWIKGHSERQSLNRNGLRRQNLTRDCHTRQMKHSGWVVHQPCPRQYNY
What is the function of this protein?
Antiproliferative and proapoptotic protein involved in cell stress response which acts as a dual regulator of transcription and autophagy.  Acts as a positive regulator of autophagy.  In response to cellular stress or activation of autophagy, relocates to autophagosomes where it interacts with autophagosome-associated proteins GABARAP, GABARAPL1/L2, MAP1LC3A/B/C and regulates autophagy.  Acts as an antioxidant and plays a major role in p53/TP53-driven oxidative stress response.  Possesses both a p53/TP53-independent intracellular reactive oxygen species (ROS) regulatory function and a p53/TP53-dependent transcription regulatory function.  Positively regulates p53/TP53 and p73/TP73 and stimulates their capacity to induce apoptosis and regulate cell cycle.  In response to double-strand DNA breaks, promotes p53/TP53 phosphorylation on 'Ser-46' and subsequent apoptosis.  Acts as a tumor suppressor by inducing cell death by an autophagy and caspase-dependent mechanism.  Can reduce cell migration by regulating the expression of SPARC.
What are the official names of this protein?
Tumor protein p53-inducible nuclear protein 1, Stress-induced protein, Thymus-expressed acidic protein, TEAP, p53-dependent damage-inducible nuclear protein 1, p53DINP1.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Nucleus, PML body. Cytoplasmic vesicle, autophagosome. Note=Shuttles between the nucleus and the cytoplasm, depending on cellular stress conditions, and re-localizes to autophagosomes on autophagy activation. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm.
Protein: VG59_SHV21
Sequence: MADTQTTHFSYGVGFKPCVLQEHTKIYNHIKAKVKDGIIQIEGLTSSPSLRIWSSIGEGILSFKINNVVSEVFNCHMMPENVSVSFRNISPGGNTFLYTRELFGCNVKTATLMFSNRSGKPFEFIKAKLEYCDKVSTTRHTSTIPAGILPFVENVNSTSVLSRVVLSPKTAAMLQKWLREHKAHKTVSVMVNSTLAVLILTVEDSTKTVDLHIVDDMSLCNNPSKDWGVVQNDVQTKVNITALSAALGLCKIPGVFVPCIKFYESEVLEVCGTPVKLGSWVDTSLQVTLFCTPNLAEDTQAAVSDYFPISPSACLTADPADTQEEPTLSSNCQDSSVENSPALPLKRKREKDINKKSKKIKIAFNPLI
What are the official names of this protein?
Gene 59 protein.
Protein: ARC_BIFAB
Sequence: MGMGQEKHTDAASQSRDPEAVAAHENDQLRQRNHALAKALTRATEELRKAKAQLEQFMAPPLTMATMVRVHRCSTDEHGVRHASAEILNGNRRQIVPLSPTVNPAQLGSGQGVLLDANMVIVDSCETPTTGPMRAVSESLADGRLIVSDVGGNRGVVMRASAVARTPINVDDRVVIDPSGTYVLSVLPQEQAQDLLLEETPDVSFTDIGGLDEQIARIRDAVQLPFQHRDLFDRFDLKAPKGVLLYGPPGNGKTLIAKAIAHELAAGSGNDGVFLSVKGPELLNKFVGESERLIRRIFERAKELSGAGRPVIVFIDEMDSLLRTRGTGVSSDVETTIVPQFLTELDGVESLDDVMVIGASNRIDMIDPAVLRPGRLDVKIHVTRPDETAAMAITRHYLTDALPLEPGRDADALAASLVRDLFRRDESRLLATLDEQGRRRGIYMADIVSGAMLRNIVDRAKTKAVKAEILHGSVSRDDEPQGITEARIHEAIDDEYEQNRSTINETDPGQWLRINALTLAADGV
What are the official names of this protein?
AAA ATPase forming ring-shaped complexes, ARC.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
Protein: KS6C1_HUMAN
Sequence: MTSYRERSADLARFYTVTEPQRHPRGYTVYKVTARVVSRRNPEDVQEIIVWKRYSDFKKLHKELWQIHKNLFRHSELFPPFAKGIVFGRFDETVIEERRQCAEDLLQFSANIPALYNSKQLEDFFKGGIINDSSELIGPAEAHSDSLIDTFPECSTEGFSSDSDLVSLTVDVDSLAELDDGMASNQNSPIRTFGLNLSSDSSALGAVASDSEQSKTEEERESRSLFPGSLKPKLGKRDYLEKAGELIKLALKKEEEDDYEAASDFYRKGVDLLLEGVQGESSPTRREAVKRRTAEYLMRAESISSLYGKPQLDDVSQPPGSLSSRPLWNLRSPAEELKAFRVLGVIDKVLLVMDTRTEQTFILKGLRKSSEYSRNRKTIIPRCVPNMVCLHKYIISEESVFLVLQHAEGGKLWSYISKFLNRSPEESFDIKEVKKPTLAKVHLQQPTSSPQDSSSFESRGSDGGSMLKALPLKSSLTPSSQDDSNQEDDGQDSSPKWPDSGSSSEEECTTSYLTLCNEYGQEKIEPGSLNEEPFMKTEGNGVDTKAIKSFPAHLAADSDSPSTQLRAHELKFFPNDDPEAVSSPRTSDSLSRSKNSPMEFFRIDSKDSASELLGLDFGEKLYSLKSEPLKPFFTLPDGDSASRSFNTSESKVEFKAQDTISRGSDDSVPVISFKDAAFDDVSGTDEGRPDLLVNLPGELESTREAAAMGPTKFTQTNIGIIENKLLEAPDVLCLRLSTEQCQAHEEKGIEELSDPSGPKSYSITEKHYAQEDPRMLFVAAVDHSSSGDMSLLPSSDPKFQGLGVVESAVTANNTEESLFRICSPLSGANEYIASTDTLKTEEVLLFTDQTDDLAKEEPTSLFQRDSETKGESGLVLEGDKEIHQIFEDLDKKLALASRFYIPEGCIQRWAAEMVVALDALHREGIVCRDLNPNNILLNDRGHIQLTYFSRWSEVEDSCDSDAIERMYCAPEVGAITEETEACDWWSLGAVLFELLTGKTLVECHPAGINTHTTLNMPECVSEEARSLIQQLLQFNPLERLGAGVAGVEDIKSHPFFTPVDWAELMR
What is the function of this protein?
May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell (PubMed:12077123).  Plays a role in the recruitment of PRDX3 to early endosomes (PubMed:15750338).
What are the official names of this protein?
Ribosomal protein S6 kinase delta-1, S6K-delta-1, 52 kDa ribosomal protein S6 kinase, Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein, SPHK1-binding protein.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. S6 kinase subfamily.
Protein: RECF_BACAN
Sequence: MFISEIQLKNYRNYEKLELSFEDKVNVIIGENAQGKTNLMEAIYVLAMAKSHRTSNDRELIRWDEDFGQIKGKLQKRNSSLSLELNISKKGKKAKLNQLEQQKLSQYIGVMNVVMFAPEDLNLVKGSPQVRRRFLDMELGQIAPVYLYELSQYQKVLTQRNHLLKKMQGNSKNEETMLDVFTLQLIEHGTKILRKRFEFLHLLQEWAAPIHRGISRGLEELEIVYKPSVDVSESMDLSKIKEVYYESFQSVKQREIFRGTTLIGPHRDDLQFFVNSKNVQVFGSQGQQRTTALSLKLAEIELIYSEVKEYPILLLDDVLSELDDYRQSHLLNTIQGKVQTFVTTTSVDGIEHETLKEAKTIHVTNGTVDCEIDRA
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRD_SHIB3
Sequence: MYYPFVRKALFQLDPERAHEFTFQQLRRITGTPFEALVRQKVPAKPVNCMGLTFKNPLGLAAGLDKDGECIDALGAMGFGSIEIGTVTPRPQPGNDKPRLFRLVDAEGLINRMGFNNLGVDNLVENVKKAHYDGVLGINIGKNKDTPVEQGKDDYLICMEKIYAYAGYIAINISSPNTPGLRTLQYGEALDDLLTAIKNKQNDLQAMHHKYVPIAVKIAPDLSEEELIQVADSLVRHNIDGVIATNTTLDRSLVQGMKNCDQTGGLSGRPLQLKSTEIIRRLSLELNGRLPIIGVGGIDSVIAAREKIAAGASLVQIYSGFIFKGPPLIKEIVTHI
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RS15_CHLTA
Sequence: MSLDKGTKEEITKKFQLHEKDTGSADVQIAILTEHITELKEHLKRSPKDQNSRLALLKLVGQRRKLLEYLNSTDTERYKNLIARLNLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: PHAC_SYNY3
Sequence: MFLLFFIVHWLKIMLPFFAQVGLEENLHETLDFTEKFLSGLENLQGLNEDDIQVGFTPKEAVYQEDKVILYRFQPVVENPLPIPVLIVYALVNRPYMVDLQEGRSLVANLLKLGLDVYLIDWGYPSRGDRWLTLEDYLSGYLNNCVDIICQRSQQEKITLLGVCQGGTFSLCYASLFPDKVKNLVVMVAPVDFEQPGTLLNARGGCTLGAEAVDIDLMVDAMGNIPGDYLNLEFLMLKPLQLGYQKYLDVPDIMGDEAKLLNFLRMEKWIFDSPDQAGETYRQFLKDFYQQNKLIKGEVMIGDRLVDLHNLTMPILNLYAEKDHLVAPASSLALGDYLPENCDYTVQSFPVGHIGMYVSGKVQRDLPPAIAHWLSERQ
What is the function of this protein?
When expressed in E. coli with Synechocystis PhaE and C. necator PhaA and PhaB, confers the ability to synthesize up to 13% (w/w) poly(3-hydroxybutyrate) (PHB) depending on the carbon source; all 4 genes are necessary for PHB production (PubMed:9683655).  Cell-free in vitro coexpression with PhaE gives a heterodimer able to polymerize 3-hydroxybutyrate-CoA (PubMed:25629766).
What are the official names of this protein?
Poly(3-hydroxyalkanoate) polymerase subunit PhaC, PHA polymerase, PHB synthase subunit PhaC, Poly(3-hydroxybutyrate) polymerase subunit PhaC, PHB polymerase, Poly(hydroxyalkanoic acid) synthase subunit PhaC, PHA synthase, Polyhydroxyalkanoic acid synthase subunit PhaC.
What is the protein family that this protein belongs to?
Belongs to the PHA/PHB synthase family. Type III PhaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2881_ARATH
Sequence: MVRAFAYEEIGETSTEAHASVEDNKRDRTRRVINYNLRSTTMISSLSKRLKIDECKNQDPEQNPNRVASSPSLCHVKSKRPQKGVSNKPILDMDFLNEEELEKIDRHYKKISDSDKGADVILVNSEGLQRKLKLKRWDMTSTSNYVLGSGWNKVVTENILETGTRLRLWSFHSPDMLFFALVLSDPDLAPTKDWECLNLLAKLTVETACLEASQDADTMSSLVSDTELDLELRL
What are the official names of this protein?
Putative B3 domain-containing protein At2g18810.
What are the subcellular locations of this protein?
Nucleus.
Protein: PCNA_NITMS
Sequence: MTFGAKTSGSDDLKAIISAISTLVEEATFVATAEGISFRGMDPSHVALIDISWPNSAFEKYECDSDIKFGVRIDEFSKLIKRADKKDSIEISISEQNMLLVTVGKNKKYKMRLIESSATDTPLPKIPYDSKIILSSSKFDKILGDVQVVSDYLTIHTSDSKGDFSGKGDSGEVVIDLDKDDEGIEEISSKEDSVGTYSLEYLNPVVKAVGTTAGFITCEFSSAKPLRIEFKVANIGRIHFYLAPRVES
What is the function of this protein?
Sliding clamp subunit that acts as a moving platform for DNA processing.  Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
What are the official names of this protein?
DNA polymerase sliding clamp, Proliferating cell nuclear antigen homolog, PCNA.
What is the protein family that this protein belongs to?
Belongs to the PCNA family.
Protein: Y025_BORBU
Sequence: MSGHSKWSTIKRKKGALDAKRNKIFTKLIREITIAAKIGGGDIESNPRLRVAVNKAKVANMPKDNIEKAIKKGIGGNEGVEYFEITYEAYAPYGVALMIKCLTDNKNRTSSDVKSVLAKGGGSLGTPGSVSYMFYRKGLIVYNLEKYLEDEIMEFALEVGAEDILVSNNEAEVITSPDDFDKVLSFLKTKFKEEVAEIALIPENKISLNKDQAEKIILLVEKLEDFDDVQEVIHNLEIPEELS
What are the official names of this protein?
Probable transcriptional regulatory protein BB_0025.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS2_THAPS
Sequence: MMIFSTAVLRLCATSRIGAVTKRASSTFLSSASSSSSSSSPTQSMPPQRYTHHQFQRHSYSTTTTTLQQQQQPSPPLSTAQLVKQLRLLTGAPMLECKKALASPDVNNDLALAQEWLRKHSSQKIGSKVAGREALEGLVGVCIDNCDGGSRGVLVKVASETDFASRSEVFTGLVQEIADAAAAAAGDGGDIVDIPTFLSNTQSITTGKLLSECLNDAVLSIRENIQLDSIVTIGTTPSSRSVIAGYVHGRAPNSTCGTSAALVEVEVLPKDGGGGDDAVLSEEEKSVAMEAAKKLAMHVVASNPLYLNPESVPVDVVEKEREILMEKMTDSNKPPEIIEKIISGQLRKFYEGICLTEQSHLVEEGNPKISKVMKGLGLVVKDFRLVGMSK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts 2, mitochondrial, EF-Ts 2, EF-TsMt 2.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: WTF19_SCHPO
Sequence: MKNKYYPLRSSMDELSAKNDNEIDLEKGPLPEYNSEDGSTLPPYSENINLKDPKQMGANNPNLFNTDESTTPPDYGEDSLSITHRENHSSGTADNSSTSPLKKAFLSFISIFVLNVPAVCYLTYKDALFKDYGKDEWVYFAVWCASCLMIFISLWYFYETWIKAVKVTVIFLAQCIKVTVVFLAQCVKVTSISLAKCVKLTAVFLAQCVKVTAVFLAQCVKVISIGLFNIRREMMIIIWLLWLIICCILFGCVKSGDLNLNKALIYSTCTISAVLLLIVSSVCIPFWTFERTLAKLAKVFLLQSGIVLVLNGTMFLRGKHFEWTGCEIEASVLFIMGNVLFLCEMECPGALIRTRNSIRNGIAFILEGAGRAIRGANDNNDIPLGEMEVESEV
What is the function of this protein?
Forms toxic aggregates that disrupt spore maturation.
What are the official names of this protein?
Meiotic driver wtf19.
What is the protein family that this protein belongs to?
Belongs to the WTF family.
What are the subcellular locations of this protein?
[Isoform 1]: Spore membrane; Multi-pass membrane protein. Vacuole membrane; Multi-pass membrane protein. Note=Contained within spores expressing the isoform and localizes isoform 2 to the vacuole. SUBCELLULAR LOCATION: [Isoform 2]: Ascus epiplasm. Cytoplasm. Spore membrane; Multi-pass membrane protein. Vacuole membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Localizes in trans to all spores within an ascus. Localization to the spore vacuole is dependent on isoform 1.
Protein: Y475_BACAC
Sequence: MDLSVKSEENVEYMVEAIKEKLRMVNAGAMRAASFNEEMYEDLRDIYEHVMKRETFSISEMQAITEELGTLIKK
What are the official names of this protein?
UPF0435 protein BAMEG_0475.
What is the protein family that this protein belongs to?
Belongs to the UPF0435 family.
Protein: EFG_CHESB
Sequence: MAREFKIEDYRNFGIMAHIDAGKTTTTERILYYTGKSHKIGEVHDGAATMDWMEQEQERGITITSAATTTFWKGRDEKLRRFNIIDTPGHVDFTIEVERSLRVLDGAIALLDANAGVEPQTETVWRQADKYHVPRMIFCNKMDKIGADFYRSVEMVKSRLGATAVVMQLPIGAESDFKGVIDLVEMKALIWRDETLGAAWDVVEIPAEFKEKAEEYREKLIEAAVEMDEGAMERYLEGEMPSIEEIRALVRKGTIEVKFFPMFCGSAFKNKGVQPLLDAVVDFLPSPIDIPAIKGVDAKTEEPIERHAEDSEPLSMLAFKIMNDPFVGSLTFCRIYSGVLKKGVSLENTVKGKRERIGRMLQMHANSREDIEEAYAGDIVALAGLKETTTGDTLCDPLKPVILERMEFPEPVIQIAIEPKTKGDQEKMGLALNRLAAEDPSFRVKTDEESGQTIIAGMGELHLDIIVDRMKREFKVEANIGAPQVAYRETITKTAEIDYTHKKQTGGSGQFARVKIVFEPNPDGEDFLFESKIVGGSVPKEYVPGVQKGIESVLSSGPIAGFPMLGVKATLVDGAYHDVDSSVLAFEIAARAAFREGAQKAGAQLLEPIMKVEVVTPEEYVGSVIGDLNSRRGQIQGQEARGVAVVVNAMVPLANMFKYVDNLRSMSQGRAQYTMQFDHYEPVPSAVAQEIQKKFA
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDH_RHILW
Sequence: MARNKIALIGSGMIGGTLAHLAGLKELGDIVLFDIADGIPQGKGLDISQSSPVEGFDVNLTGASDYSAIEGADVCIVTAGVARKPGMSRDDLLGINLKVMEQVGAGIKKYAPNAFVICITNPLDAMVWALQKFSGLPANKVVGMAGVLDSSRFRLFLAKEFNVSVQDVTAFVLGGHGDTMVPLARYSTVGGIPLTDLVTMGWVTKERLEEIIQRTRDGGAEIVGLLKTGSAYYAPAASAIEMAESYLKDKKRVLPCAAHLSGQYGVKDMYVGVPTVIGAGGVERIIEIDLNKTEKEAFDKSVGAVAGLCEACINIAPALK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: PYRH_PYRAR
Sequence: MALVLKISGRVFDNEELVLKYAEILNKLPGRIAVVAGGGEVARRYIAVARKGGASNTFQDLLGIYASRLNALLLISLLKDAYAKVPRNMEEFLEAWGRSRIVVTGGFQPGQSTATVAALVAEAVRAAALLNAANIDAVYSDDPRKNPNATRLSELKYDEFERILRSSNLPGGYELIDTWAVSILKRSCITTYIFDGRTPEAIEAVVRGENPGSKITC
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2335_VIBPA
Sequence: MQVYGCCELVRELYAQIGSGDQAYIPQAISCAVKALNDVAADESLPKEVREKAAFAAANLLISDFEDK
What are the official names of this protein?
UPF0253 protein VP2335.
What is the protein family that this protein belongs to?
Belongs to the UPF0253 family.
Protein: SYT_SALDC
Sequence: MPVITLPDGSQRHYDHPVSPMDVALDIGPGLAKATIAGRVNGELVDASDLIENDATLAIITAKDEEGLEIIRHSCAHLLGHAIKQLWPHTKMAIGPVVDNGFYYDVDLDRTLTQEDVEALEKRMHELAEKNYDVIKKKVSWHDARETFVKRGETYKVAILDENIAHDDKPGLYHHEEYVDMCRGPHVPNMRFCHHFKLMKTAGAYWRGDSNNKMLQRIYGTAWADKKALNAYLQRLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGALHGLMRVRGFTQDDAHIFCTEEQIRDEVNACIRMVYDMYSTFGFEKIVVKLSTRPDKRIGSDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPVMIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVVMNITDSQSEYVNELTQKLQNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVEAGKVAVRTRRGKDLGSLDVNDVIEKLQQEIRSRSLQQLEE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: O1102_MOUSE
Sequence: MPRTPSYTNTKTTQVNNVTEITVFILLGFTDDVDMNIFLFILFLAIYVVTLIGNLGLVVLVIEDSRLHNPMYYFLTVLSSLDACFSSVLTPKMLVNFLSKNKSISFAGCATQMLLFVTFGTTECFLLAAMAYDRYLAIYSPLLYAVRMSPRVYVPLIIASYTGGILHATIHTVATFSLSFCGSNEIRHVFCDIPPLLALSCSDTHLNQLLLFYCAGSIELITILIVLVSYGFVLLAILKINSAEGRRKIFSTCGAHLTGVSIFHGTILFMYVRPSSNYTLEQDMVVSTFYTIVIPMLNPIIYSLRNKDVKEAMRKLLKRKLVHE
What is the function of this protein?
Potential odorant receptor.
What are the official names of this protein?
Olfactory receptor 1102, Olfactory receptor 179-4.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HIS1_PECCP
Sequence: MLDKTRLRIAMQKSGRLSDDSRELLARCGIKINLQQQRLIAFAENMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYFTLRRLDFGGCRLSLAMPLDEDYTGPECLQNKRIATSYPHLLKQYLDRKSVSFKSCLLNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMPAEKQQLIDKLLTRMQGVIQARESKYIMLHAPSERLEEVISLLPGAERPTILPLAGDQSRVAMHMVSSETLFWETMEKLKSLGASSILVLPIEKMME
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.