PharMolix/UniProtQA huggingface dataset:
Protein: GST1D_ANOGA
Sequence: MDFYYLPGSAPCRAVQMTAAAVGVELNLKLTDLMKGEHMKPEFLKLNPQHCIPTLVDNGFALWESRAIQIYLAEKYGKDDKLYPKDPQKRAVVNQRLYFDMGTLYQRFADYHYPQIFAKQPANPENEKKMKDAVGFLNTFLEGQEYAAGNDLTIADLSLAATIATYEVAGFDFAPYPNVAAWFARCKANAPGYALNQAGADEFKAKFLS
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.  Has DDT dehydrochlorinase activity.
What are the official names of this protein?
Glutathione S-transferase 1, isoform D, AgGst1-alpha, Aggst1-1, Aggst1-6, Aggst2-1, DDT-dehydrochlorinase, GST class-theta.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Theta family.
Protein: EFP_YERPN
Sequence: MASYYSNDFRPGLKIMFEGEPYAVESSEFVKPGKGQAFARVKMRRLLTGGRVEKTFKSTDSLEGADVNDMNLTYLYNDGEFWHFMNNETYEQLQADAKAVGDNGKWLIDQAECIVTLWNGQPIAVTPPNFVELEIVDTDPGLKGDTAGTGGKPATLSTGAVVKVPLFVQVGEIIKVDTRSGEYVSRVK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KANL2_BOVIN
Sequence: MNRIRIHVLPTNRGRITPVPRSQEPLSCSFTHRPCSQPRLEGQEFCIKHILEDKNAPFKQCSYVSTKNGKRCPSAAPKPEKKDGASFCAEHARRNALALHAQMKKTSPGPVGETLLCQLSSYAKTELGSQTPESSRSEASRILDEDSWSDGDQEPITVDQTWRGDPDSEADSIDSDQEDPLKHAGVYTAEEVALIMREKLIRLQSLYIDQFKRLQHLLKEKKRRYLHNRKVEHEALGSSLLTGPEGLLAKERENLKRLKCLRRYRQRYGVEALLHRQLKERRMLATDGAAQQAHTTRSSQRCLAFVDDVRCSNQSLPMTRHCLTHICQDTNQVLFKCCQGSEEVPCNKPVPVSLSEDPCCPLHFQLPPQMYKPEQDLDVVGDGMQCPPSPLLFDPSLTLEDHPVKEIAEGPVDILGQMQMAGDGCRSQGPRNSEKAPAPLPQSGIATANGKPEPTSVS
What is the function of this protein?
As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription.
What are the official names of this protein?
KAT8 regulatory NSL complex subunit 2, NSL complex protein NSL2, Non-specific lethal 2 homolog.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATP62_BRASB
Sequence: MQSSPLTSTLLFHIGPVAITRPVVTTWVIMAALALVCRFVTRRLAILPDGRQALLEGIVTSVAGQIEDVIRKDARPFLPLLGTLIIFLVVANLSGVLPGVEAPTSKIETPAALALIVFFSVHYFGVRERGLRGYLASFAEPKLIMLPLNILSEITRTFSLMVRLFGNIMSGEFIIGLVVALAGLFVPIPLMALEILVGLVQAYIFTVLATVFIGAAVGSVAKG
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a 2, ATP synthase F0 sector subunit a 2, F-ATPase subunit 6 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MURD_BORPE
Sequence: MNTTETSRAAAPLVLILGLGETGVAAARWYARQGSPLRVTDSRAQPGGLAALQAALADATVEYRLGCGEQFPPDLLDGVAQIVLSPGLVPHESPTRELLEQARERNVEVVGEIELFARALAGLAESREYRPRVLAITGTNGKTTVTALTRQLIEAGGMSARAAGNISPAALAALMDALDQDDLPQVWVLELSSFQLETTRTLAPDAAVVLNVTQDHLDWHGDMQAYAQAKARILKPARLAIVNRDDPLAVAMVESLQALNVRSFGRDVPALVGDMGLELGQGVAWLTACESNDFDEPAPAPRRKKDAPPPTRAGGRMSRLMPVDALRIRGVHNALNALAAMQLARSLDLGWGPMLRTLRDYAGEPHRAELVRSIGDVDYINDSKGTNVGATVAALEGLGQQVVLIAGGQGKGQDFSPLVPVVRRHARAVVLIGVDGAAIGKVLEPTGVPCAAAADMREAVRRAAELAQPGDAVLLSPACASFDMFRNYPHRGEVFAAEVRELALDRGEVA
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_CHLTR
Sequence: MPKMKSNKSVAARFKLTGSGQLKRTRPGKRHKLSKRSSQQKRNLSKQPLVDQGQVGMYKRMMLV
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: AQPA_PELLE
Sequence: MASEFKKKAFWRAVIAEFLAMILFVFISIGAALGFNFPIEEKANQTVGRSQDIVKVSLAFGISIATMAQSVGHVSGAHLNPAVTLGCLLSCQISILKAVMYIIAQCLGAVVATAILSGITSGLENNSLGLNGLSPGVSAGQGLGVEILVTFQLVLCVVAVTDRRRHDVSGSVPLAIGLSVALGHLIAIDYTGCGMNPARSFGSAVLTKNFTYHWIFWVGPMIGGAAAAIIYDFILAPRTSDLTDRMKVWTNGQVEEYELDGDDNTRVEMKPK
What is the function of this protein?
Forms a water-specific channel.
What are the official names of this protein?
Aquaporin FA-CHIP.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GLYCO_VSNJO
Sequence: MLSYLIFALAVSPILGKIEIVFPQHTTGDWKRVPHEYNYCPTSADKNSHGTQTGIPVELTMPKGLTTHQVEGFMCHSALWMTTCDFRWYGPKYITHSIHNEEPTDYQCLEAIKSYKDGVSFNPGFPPQSCGYGTVTDAEAHIVTVTPHSVKVDEYTGEWIDPHFIGGRCKGQICETVHNSTKWFTSSDGESVCSQLFTLVGGIFFSDSEEITSMGLPETGIRSNYFPYISTEGICKMPFCRKQGYKLKNDLWFQIMDPDLDKTVRDLPHIKDCDLSSSIITPGEHATDISLISDVERILDYALCQNTWSKIESGEPITPVDLSYLGPKNPGVGPVFTIINGSLHYFTSKYLRVELESPVIPRMEGKVAGTRIVRQLWDQWFPFGEVEIGPNGVLKTKQGYKFPLHIIGTGEVDSDIKMERVVKHWEHPHIEAAQTFLKKDDTGEVLYYGDTGVSKNPVELVEGWFSGWRSSLMGVLAVIIGFVILMFLIKLIGVLSSLFRPKRRPIYKSDVEMAHFR
What is the function of this protein?
Attaches the virus to host cellular receptor, inducing clathrin-dependent endocytosis of the virion.  In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and endosomal membrane.  In neurons, neo-synthesized glycoproteins are sorted to the dendrites, where the virus buds (By similarity).
What are the official names of this protein?
Glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the vesiculovirus glycoprotein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host membrane; Single-pass type I membrane protein.
Protein: MINE_HELAH
Sequence: MSLFDFFKTKGSAATATDRLKLILAKERTLNLPYMEEMRKEIIAVIQKYTKSSDIHFKTLDSNQSVETIEVEIILPK
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: PYRE_STRA1
Sequence: MDLARQIAMELLDIQAVYLRPKQPFTWASGVKSPIYTDNRVTLSYPETRTLIENGFVKQIQEHFPNVDIIAGTATAGIPHGAIIADKMNLPFAYIRSKAKDHGVGNQIEGRVYSGQKMVIIEDLISTGGSVLEAVTAAQSQGIEVLGVVAIFTYQLAKAEQAFREANIPLVTLTDYNQLIKVAKVNGYITADQLVLLKKFKEDQMNWQS
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: DAPB_PARMW
Sequence: MTPSIPVVVAGALGRMGAEVIKAVVGSADCMLVGAIDNTPGKEGSDIGLELGLGELEVAVTADFEGCLCAVSQSVRDAEAGAVLVDFTHPSVVYEHTRAAIAYGVHPVIGTTGLSPEQLSDLCQFAAKASIGGAVIPNFSVGMVLLQQAAAAAARFYDHAELTELHHNCKADAPSGTCIKTAELMEELGKSFNPAEVDEHESLAGSRGGRRESGLRLHSLRLPGLVAHQEVMFGAPGETYTLRHDTIDRSAYMPGVLLTVRKVRSLQTLVYGLERLI
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENGB_CHRVO
Sequence: MSIFQNARFYTTVNHMKDLPATRAEVAFVGRSNAGKSSAINTLANRTRLAYVSKTPGRTQHINFFELGDECFLVDLPGYGYAEVPEAVRAHWVELLGRYLQTRQSLIGLLLIMDARHPLKELDRRMLEFFRVAGRPVHILLSKADKLSRQEQNKVLAEVKRELADYPSVSVQMFSSLKKTGVDVVEQVVKGWFDALPPQDDGMAEL
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: ACCA_HALHL
Sequence: MTKNFLDFEQPIAELEAKIEELRNVGQDSEVNINEEIQRLEAKSRSLTEKIFSSLSAWQIVQLARHPERPYLFDYIERIFTDFQELHGDRAYADDAAIAGGVARFDGRPVMVIGQQKGRDTKEKVRRNFGMPRPEGYRKALRLMRMAERFGLPIFTFIDTPGAYPGVGAEERGQSEAIARNLAEMAQLRVPVICTVVGEGGSGGALAISVGNRLLMLRYSVYSVISPEGCASILWKSSERAADAAEAMQMAAERLHDLGIVDRVIPEPLGGAHRDYEAMAETLREALREEWARVGQMSPDELVADRHQRLAAIGQPQG
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYL4_MOUSE
Sequence: MPPKKPEPKKEAAKPAAAPAPAASAAPEPLKDSAFDPKSVKIDFSADQIEEFKEAFSLFDRTPTGEMKITYGQCGDVLRALGQNPTNAEVLRVLGKPKPEEMSSKTLDFEMFLPILQHISRNKEQGTYEDFVEGLRVFDKESNGTVMGAELRHVLATLGEKMSEAEVEQLLSGQEDANGCINYEAFVKHIMSG
What is the function of this protein?
Regulatory light chain of myosin.  Does not bind calcium.
What are the official names of this protein?
Myosin light chain 4, MLC1EMB, Myosin light chain 1, atrial/fetal isoform, MLC1A.
Protein: PSBL_AETGR
Sequence: MTQSNPNEQNVELNRTSLYWGLLLIFVLAILFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: H4_PSEMZ
Sequence: ISGLIYEETRIFLENVIR
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H4.
What is the protein family that this protein belongs to?
Belongs to the histone H4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: CMOB_HAEIN
Sequence: MIDFRPFYQQIATTNLSDWLETLPCQLKEWETQTHGDYAKWSKIVDFLPNLHADEIDLKSAVKSDRTSPLSEGEKQRIIHHLKQLMPWRKGPYHLFGIHVDCEWRSDFKWDRVLPHLSPLQGRTILDVGCGSGYHMWRMVGEGAKMVVGIDPTELFLCQFEAVRKLLNNDRRANLIPLGIEQMQPLAAFDTVFSMGVLYHRKSPLDHLSQLKNQLVKGGELVLETLVVDGDINTVLVPADRYAKMKNVYFIPSVATLINWLEKVGFTNVRCVDVATTTLEEQRKTDWLENESLIDFLDPNDHSKTIEGYQAPKRAVILANK
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: PTN6_HUMAN
Sequence: MVRWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKVMCEGGRYTVGGLETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESEDTAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPGSDYINANYIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYWPEVGMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQESEYGNITYPPAMKNAHAKASRTSSKHKEDVYENLHTKNKREEKVKKQRSADKEKSKGSLKRK
What is the function of this protein?
Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR.  The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates.  Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation.  Plays a key role in hematopoiesis.
What are the official names of this protein?
Tyrosine-protein phosphatase non-receptor type 6, Hematopoietic cell protein-tyrosine phosphatase, Protein-tyrosine phosphatase 1C, PTP-1C, Protein-tyrosine phosphatase SHP-1, SH-PTP1.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=In neurons, translocates into the nucleus after treatment with angiotensin II (By similarity). Shuttles between the cytoplasm and nucleus via its association with PDPK1.
Protein: DMDB_DROME
Sequence: MTAKPPPPIPPTLGGDDSGTHGPKLAPEIPRINSELAAQAALRGQQLLRKQGSQEQHATNTLPAHKTGAPPPLPPTQSRPVPAIPARGASDRAAPPEIPPKRHSLKSMPDGQPMMVPGLPPTMRQPPPLPRKPASTQSSAQNSAQSSPLAGMKFKDKPPPPPEKHSTLSAEGMAARRCSNPFEMPPPPPPLVLQSAVAALSEQSSKNGLNPVPSPAPTRASEAKKINQRSIASPTEEFGSEDALRGIESGLRNMERAMQEQMNLRNMEAAVQNNFDLSFKASLAAGARHLGGGSVNLRTANYERNLSLDEGRAGDSRQSLEELKQLRAQAQQQSLLNNSSSSSSNSQVEQSMRSTIEHHMRSLDRNLPLELQYSRHRFQNNLNAVAAAGGGGGNSSTGNAVANSGTSGSQQPPMPLSSEFREQIRQQLLGNIPPQVVHNMGQSPGSAAAAALLQHQAQSRAAAAAAAAAAAAAAAQVAAGSGALSREELRMRRRSSHDETQLTQNSSGGIQVTRLREHWDETSQCVLQRAAQLKNMLSDSQRFEAKRLELEKWLARMEQRAERMGTIATTADILEAQQKEQKSFHAELHQNKQHFDIFNELTQKLIAVYPNDDTTRIKKMTEVINQRYANLNSGVINRGKQLHAAVHSLQSFDRAMDQFLAFLSETETLCENAESDIERNPLMFKDLQSEIETHRVVYDRLDGTGRKLLGSLTSQEDAVMLQRRLDEMNQRWNNLKSKSIAIRNRLESNSEHWNALLLSLRELTEWVIRKDTELSTLGLGPVRGDAVSLQKQLDDHKAFRRQLEDKRPIVESNLTSGRQYIANEAAVSDTSDTEANHDSDSRYMSAEEQSRELTRSIRREVGKLSEQWNNLIDRSDNWKHRLDEYMTKMRQFQKILEDLSSRVALAEQTKTSWLPPSSVGEANEQMQQLQRLRDKMTTASALLDDCNEQQSFFTANQVLVPTPCLSKLEDLNTRMKLLQIAMDERQKVLCQAGAQQTHENGDDGRTTSNSGTIGPLPNLGQSVKPPWERATTAANVPYYIDHERETTHWDHPEMIELMKGLADLNEIRFSAYRTAMKLRSVQKRLALDRISMSTACESFDRHGLRAQNDKLIDIPDMTTVLHSLYVTIDKIDLTLMLDLAINWILNVYDSQRTGQIRVLSFKVGLVLLCKGHLEEKYRYLFRLVADTDRRADQRRLGLLLHDCIQVPRQLGEVAAFGGSNIEPSVRSCLEQAGISQEAIDGNQDISIELQHFLGWLQHEPQSLVWLPVLHRLAAAEAAKHQAKCNICKEYPIVGFRYRCLKCFNFDMCQKCFFFGRNAKNHKLTHPMHEYCTTTTSTEDVRDFTRALKNKFKSRKYFKKHPRVGYLPVQSVLEGDALESPAPSPQHTTHQLQNDMHSRLEMYASRLAQVEYGGTGSNSTPDSDDEHQLIAQYCQALPGTSNGSAPKSPVQVMAAMDAEQREELEAIIRDLEEENANLQAEYQQLCSKEQSGMPEDSNGMQHSSSSMTGLSGQGEQGQDMMAEAKLLRQHKGRLEARMQILEDHNRQLEAQLQRLRQLLDEPNGGGSSATSSGLPSAPGSALNSKPNTLQTRSVTASQLNTDSPAKMNQQNGHYEHNSKNSSGLVTVITEQELESINDDLEDSSSSNTTNTTTTTTTTATTEKTCVELQK
What is the function of this protein?
Required for the maintenance of appropriate synaptic retrograde communication and the stabilization of muscle cell architecture or physiology.  May play a role in anchoring the cytoskeleton to the plasma membrane.
What are the official names of this protein?
Dystrophin, isoform B, Protein detached.
What are the subcellular locations of this protein?
Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton.
Protein: GCH1_VIBVU
Sequence: MSGLSESAQLVKQALEKRGLETPMVPNQFSREEKKEKIEHHMREILSLLELDLTDDSLEETPRRIAKMYVDEVFSGLDYQNFPKITVIENKMNVSEMVRVKEITLTSTCEHHLVTIDGKAAVAYIPRGKIIGLSKINRIVRFFAQRPQVQERMTQQILVALQTLLESDDVAVTIDATHYCVKSRGVMDATSETTTTALGGIFKSNPATRAEFLHGLR
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: ASSY_ACICJ
Sequence: MAENSVKKVVLAYSGGLDTSVILRWLQTERGAEVVTFTADLGQGEELEPARRKAEMFGVKEIFVEDLRETFVKDFVFPMFRANALYEGQYLLGTSIARPLIAQRQIEIAEAVGADAVAHGATGKGNDQVRFELAYYALKPDVKVVAPWREWSLTSRTKLLEFAEAHQIPIAKDKRGEAPFSVDANLLHSSSEGKILEDPAQAPDEIVYQRTISPEAAPDVVTEISIDFAQGDAVALNGVALSPATLLTRLNELGRDNGIGRLDLVENRFVGMKSRGVYETPGGTILLAAHRAIESITLDREAAHLKDSLMPRYAELIYNGFWFSPERRMLQALIDASQNSVTGRVRLKLYKGNVIVAGRESPNSLYSARMVTFEDDEGAYNQQDAAGFIKLNALRLRLGGAIGRRGGAL
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYC_BRSV9
Sequence: MSNHTHHLKFKTLKRAWKASKYFIVGLSCLYKFNLKSLVQTALTTLAMITLTSLVITALIYISVGNAKAKPTSKPTIQQTQRPQNHTSPLFTEHNYKSTHTSIQSTTLSQLLNIDTTRGTTYSHPTDETQNRKIKSQSTLPATRQPPINPSGSNPPENHQDHNNSQTLPYVPCSTCEGNLACSSLCQIGLERAPSRAPTITLKKAPKPKTTKKPTKTTIHHRTSPEAKLQPKNNTAAPQQGILSSPEHHTNQSTTQI
What is the function of this protein?
Helps the virus escape antibody-dependent restriction of replication by acting as an antigen decoy and by modulating the activity of leukocytes bearing Fc-gamma receptors.
What are the official names of this protein?
Major surface glycoprotein G, Attachment glycoprotein G, Membrane-bound glycoprotein, mG.
What is the protein family that this protein belongs to?
Belongs to the pneumoviruses glycoprotein G family.
What are the subcellular locations of this protein?
[Isoform Membrane-bound glycoprotein G]: Virion membrane; Single-pass type II membrane protein. Host cell membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Isoform Secreted glycoprotein G]: Secreted. Note=The protein is shed from infected cells before the appearance of progeny virus. The initiation at the downstream methionine removes a portion of the transmembrane domain. The remaining hydrophobic portion of the sG protein is essential for translocating it into the lumen of the ER during translation and would likely maintain its membrane association until a proteolytic event releases the mature sG protein into the medium.
Protein: RL16_ECO27
Sequence: MLQPKRTKFRKMHKGRNRGLAQGTDVSFGSFGLKAVGRGRLTARQIEAARRAMTRAVKRQGKIWIRVFPDKPITEKPLAVRMGKGKGNVEYWVALIQPGKVLYEMDGVPEELAREAFKLAAAKLPIKTTFVTKTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: ARGC_SULDN
Sequence: MSAIDVGVIGASGYTGLELIKILLKHPKFNLSYVANTEGGATLSELHPSLKGAFECNVVKVDIDELAKKCELVFLAVPHQAAMAYVKPLIEKGLKVVDLSADYRLSKDIYEEFYCPHTDVENLLHAVYGLPELFAQKIKKAKLVANPGCFPTSAILGLLPFMDKRVAHTPIIVDSKTGVSGAGKKLSDVTHFVNVNENLFAYNPLLHRHAPEIAQKLGVDFDEVHFVPHLVPVTRGMLSSIYIQVEGDFDAFSILSEFYKDAKHVRVSKNPVDMKSVAGTNFCDIYVKQKNNILFISSAIDNLMRGASSAAVVNANLMMGFDEELGIPNIAYVP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1169_YERE8
Sequence: MEIRVFQQSDFEEVILLWEHCDLLRPWNDPEMDIERKLNHDPELFLVAEVSGAIVGSVMGGYDGHRGSAYYLGVHPDFRGRGFANALISRLEKKLIARGCPKLNIMVREDNDAVIGMYEKLDYETQDTIMLGKRLIVDQEY
What are the official names of this protein?
Acetyltransferase YE1169.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. YpeA subfamily.
Protein: VPS36_RAT
Sequence: MDRFVWTSGLLEINETLVIQQRGVRVYDGEEKIKFDAGTLLLSTHRLIWRDQKNNECCMAIPLSQIVFIEEQAAGIGKSAKIVVHLHPAPPNKEPGPFQSSKNSYIKLSFKEHGQIEFYRRLSEEMTQRRWETVPVSQSLQTKKGPQPGRIRAVGIVGIERKLEEKRKETDKNISEAFEDLSKLMIQAKEMVELSKSIANKIKEKQGDVTEDETIRFKSYLLSMGIANPVTRETYGSGTQYHMQLAKQLAGILQAPLEERGGIMSLTEVYCLVNRARGMELLSPEDLVNACKMLEGLKLPVRLRVFDSGVMVIELQTHKEEEMVASALETVSERGSLTSEEFAKLVGMSVLLAKERLLLAEKMGHLCRDDSVEGLRFYPNLFMTQN
What is the function of this protein?
Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.  The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation.  The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex.  Its ability to bind ubiquitin probably plays a role in endosomal sorting of ubiquitinated cargo proteins by ESCRT complexes.  The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL.  Binds phosphoinosides such as PtdIns(3,4,5)P3 (By similarity).
What are the official names of this protein?
Vacuolar protein-sorting-associated protein 36, ELL-associated protein of 45 kDa, ESCRT-II complex subunit VPS36.
What is the protein family that this protein belongs to?
Belongs to the VPS36 family.
What are the subcellular locations of this protein?
Cytoplasm. Endosome. Late endosome. Membrane. Nucleus. Note=Colocalizes with ubiquitinated proteins on late endosomes. Recruited to the endosome membrane to participate in vesicle formation.
Protein: GLU2B_MOUSE
Sequence: MLLLLLLLLPLCWAVEVKRPRGVSLSNHHFYEESKPFTCLDGTATIPFDQVNDDYCDCKDGSDEPGTAACPNGSFHCTNTGYKPLYILSSRVNDGVCDCCDGTDEYNSGTVCENTCREKGRKEKESLQQLAEVTREGFRLKKILIEEWKTAREEKQSKLLELQAGKKSLEDQVETLRAAKEEAERPEKEAKDQHRKLWEEQQAAAKARREQERAASAFQELDDNMDGMVSLAELQTHPELDTDGDGALSEEEAQALLSGDTQTDTTSFYDRVWAAIRDKYRSEVPPTDIPVPEETEPKEEKPPVLPPTEEEEEEEEEPEEEEEEEEEEEEAPPPLQPPQPPSPTEDEKMPPYDEETQAIIDAAQEARSKFEEVERSLKEMEESIRSLEQEISFDFGPSGEFAYLYSQCYELTTNEYVYRLCPFKLVSQKPKHGGSPTSLGTWGSWAGPDHDKFSAMKYEQGTGCWQGPNRSTTVRLLCGKETVVTSTTEPSRCEYLMELMTPAACPEPPPEAPSDGDHDEL
What is the function of this protein?
Regulatory subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins (PubMed:27462106, PubMed:9148925).  Required for efficient PKD1/Polycystin-1 biogenesis and trafficking to the plasma membrane of the primary cilia (PubMed:21685914).
What are the official names of this protein?
Glucosidase 2 subunit beta, 80K-H protein, Glucosidase II subunit beta, Protein kinase C substrate 60.1 kDa protein heavy chain, PKCSH.
What are the subcellular locations of this protein?
Endoplasmic reticulum.