PharMolix/UniProtQA huggingface dataset:
Protein: TTF2_MOUSE
Sequence: MDLVKCPEHGDACFLKTGVRDGPNKGKSFYVCRTNTCGFVQATDIPVSHCLLHEEFVVELQGLFLPQDKKEWRLFFRCARTKAEGKQWCGNVPWRQDPNPKELSVTSKPQQPSESQLHSPSQPRNPFRVLNKNQKTLERKQFVEEGERKTADKKLRENNEQLLDQRKEQKPKSNSRMEKDPSSDLVATRQSGGDREEQEKSKFQPKTKKAEGMASKQGHGEVLQGIPKGPHMSESESRGVPNKPETLREKETQLLVPSVPGQNPESKVQKEGHVSREPLKNGEAPSAQVTQRGLAQGPLQGPSKTWRPVPEAPAAPELCSGMAHHATSSSEDSEDDGVSSRPGSPLLFDSTVDSQKKGSLQHSDQSVQRQMPAASGVSKKGDSSDPAAQRANLTTQLKQKKGTLAAVNIQALPDKGEKLLKQIQALEDALSALALSPEQGTKEKCSAQEPEQSNITKAAAAPLHLVPPQPLPRPLIQPASSLGLKAGRQETPEGASQCSGGHMNQHHLYNVWKITSEAIDELHRSLKSCPGETAVAEDPAGLKVPLLLHQKQALAWLLWRESQKPQGGILADDMGLGKTLTMIALILTKKNQQKSKEKERSEPVTWLSKNDSSVFTSSGTLIVCPASLIHHWKNEVEKRVTSNRLRIYLYHGPNRSRHAKVLSTYDIVITTYSLLAKEIPTTKQEGEVPGANLSVEGTSAPLLQVVWARIILDEAHNVKNPRVQTSIAVCKLQAQARWAVTGTPIQNNLLDMYSLMKFLRCSPFDEFSLWKSQVDNGSMKGGERLSILTKSLLLRRTKDQLDSTGKPLVALPARRCQLHRLKLSEDERAVYDIFLARSRSALQSYLKRQEGRGSHHGRSPDNPFSRVAQEFGSSVSQGCPAADSQRPSTVHVLSQLLRLRQCCCHLSLLKSALDPTELESEGLVLSLEEQLSALTLSKVDVSEPSPTVSLNGTCFKAELFDDTRRSTKVSSLLAELEAIQKGPGSQKSVIVSQWTSMLQVVALHLKKNRLTYATIDGSVNPKQRMDLVEAFNHSQGPQVMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDRIYRVGQKKDVVIHRFVCEGTVEEKILQLQEKKKDLAKQVLSGSEGPVTKLTLADLKILFGI
What is the function of this protein?
DsDNA-dependent ATPase which acts as a transcription termination factor by coupling ATP hydrolysis with removal of RNA polymerase II from the DNA template.  May contribute to mitotic transcription repression.  May also be involved in pre-mRNA splicing (By similarity).
What are the official names of this protein?
Transcription termination factor 2, RNA polymerase II termination factor, Transcription release factor 2.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Cytoplasmic during interphase. Relocates to the nucleus as cells enter mitosis (By similarity).
Protein: PAB_FINMA
Sequence: MKLNKKLLMAALAGAIVVGGGVNTFAADEPGAIKVDKAPEAPSQELKLTKEEAEKALKKEKPIAKERLRRLGITSEFILNQIDKATSREGLESLVQTIKQSYLKDHPIKEEKTEETPKYNNLFDKHELGGLGKDKGPGRFDENGWENNEHGYETRENAEKAAVKALGDKEINKSYTISQGVDGRYYYVLSREEAETPKKPEEKKPEDKRPKMTIDQWLLKNAKEDAIAELKKAGITSDFYFNAINKAKTVEEVNALKNEILKAHAGKEVNPSTPEVTPSVPQNHYHENDYANIGAGEGTKEDGKKENSKEGIKRKTAREEKPGKEEKPAKEDKKENKKKENTDSPNKKKKEKAALPEAGRRKAEILTLAAASLSSVAGAFISLKKRK
What is the function of this protein?
Binds serum albumin.
What are the official names of this protein?
Peptostreptococcal albumin-binding protein.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor.
Protein: RT05_CAEBR
Sequence: MRRSGPELWKTLTSVSKSGQKKGRRNTRQPVRPLSRFYRIGSSPMKVEFAGLNAPMRLNDESLMTIAEQTEDEIRDLMGGTKKILEERDTGKKKRNREKLHPMERGFSGTQLVGQKLGAPPPVDGVNFDDFETYCLEVKRTSNMTNVFGRVHTMSALVVTGNGRGLAGYAVGKAPIHRTTTAIINGIGMASRKIFHVELHEGRTIYQDFYAECRNTRVFAQRRPRGFGLTCHPRLIKICEAIGIKDIYVKVEGSTKNYLALTHAFVTGLLNQETHQQLAERKGLHVVEMSPSRHFLPQIVASPISTELKTEETLEALDRLNLDDFYGEGRYPLRKPKALPFFSNLEGHLDARWRKHPFRNQESTMIRLIADNMVPRWTRDARAAWAEQRNERMTTGVEPMPLGIGLSHVVPKKDD
What are the official names of this protein?
Putative 28S ribosomal protein S5, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PNMT_THLFG
Sequence: METKQTKKEAVANLIKRIEHGEVSDEEIRGMMKIQVQKRLKWGYKPTHEQQLAQLVTFAQSLKGMEMAEEVDTLDAELYEIPLPFLHIMCGKTLKFSPGYFKDESTTLDESEVYMMDLYCERAQIKDGQSILDLGCGHGSLTLHVAQKYRGCKVTGITNSVSQKEFIMDQCKKLDLSNVEIILEDVTKFETEITYDRIFAVALIEHMKNYELFLKKVSTWIAQYGLLFVEHHCHKVFAYQYEPLDEDDWYTEYIFPSGTLVMSSSSILLYFQEDVSVVNHWTLSGKHPSLGFKQWLKRLDDNIDEVKEIFESFYGSKEKAMKFITYWRVFCIAHSQMYSTNNGEEWMLSQVLFKKK
What is the function of this protein?
N-methyltransferase with a substrate preference for (+-)-pavine, but also active with (R,S)-stylopine, (R,S)-scoulerine, (R,S)-tetrahydropalmatine, (R,S)-tetrahydropapaverine and (S)-reticuline (PubMed:19624470, PubMed:27573242).  No activity with (R)-reticuline (PubMed:27573242).  In the presence of a racemic mixture of tetrahydropapaverine (THP), one molecule of (S)-THP binds in a productive mode, while one molecule of (R)-THP is bound next to it in a non-productive mode (PubMed:27573242).  The (R)-THP may inhibit the release of products from the enzyme when higher concentrations of the racemic substrate are added to the reaction (PubMed:27573242).
What are the official names of this protein?
Pavine N-methyltransferase, PfPavNMT.
What is the protein family that this protein belongs to?
Belongs to the CFA/CMAS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DVL2_ARATH
Sequence: MESIMSLKRKEKKSQSRRLGKYLKEQKGRIYIIRRCVMMLLCSHD
What is the function of this protein?
Small polypeptide acting as a regulatory molecule which coordinates cellular responses required for differentiation, growth and development, including leaves shape, pedicule elongation, inflorescence organization and fruit maturation, probably by restricting polar cell proliferation in lateral organs and coordinating socket cell recruitment and differentiation at trichome sites.
What are the official names of this protein?
Small polypeptide DEVIL 2, Small polypeptide ROTUNDIFOLIA like 19, Small polypeptide ROT-FOUR-LIKE 19.
What is the protein family that this protein belongs to?
Belongs to the DVL/RTFL small polypeptides family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: CP51_PICKU
Sequence: MPWVGSAVVYGMQPYEFFENCRKQHGDVFSFLLLGKVMTVYLGPKGHEFVLNAKLSDVSAEDAYTHLTTPVFGKGVIYDCPNWKLMEQKKFAKVALTKESFIRYVPLIKDEMLKYFNANFRGDSGKTDVLKSQSEMTLFTASRSLFGDALRNRLDASYAEMYSDLDKGFTPLNFVFSYLPLPNYWKRDAAHKNISNTYLDLINTKRAGGEIKNEDLVDALLKNSVYKDGTRMTDEELAHLMIGVLMGGQHTSSATSAWFLLHLGEKPQLQEEIYREIQSVLGENFERELTYDDLQKLDLVNATIKETLRLHMPLHSIFRKVTRDLPVPNTSYIVPKGHYVLISPGYTMLSERYFPNASEFQPHRWDEIKSIDGGISFGAEGENAKETVDYGFGKISKGVASPYLPFGGGRHRCT
What is the function of this protein?
Sterol 14alpha-demethylase that plays a critical role in the third module of ergosterol biosynthesis pathway, being ergosterol the major sterol component in fungal membranes that participates in a variety of functions (By similarity).  The third module or late pathway involves the ergosterol synthesis itself through consecutive reactions that mainly occur in the endoplasmic reticulum (ER) membrane (By similarity).  In filamentous fungi, during the initial step of this module, lanosterol (lanosta-8,24-dien-3beta-ol) can be metabolized to eburicol (By similarity).  Sterol 14alpha-demethylase catalyzes the three-step oxidative removal of the 14alpha-methyl group (C-32) of both these sterols in the form of formate, and converts eburicol and lanosterol to 14-demethyleburicol (4,4,24-trimethylergosta-8,14,24(28)-trienol) and 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol, respectively, which are further metabolized by other enzymes in the pathway to ergosterol (By similarity).  Can also use susbtrates not intrinsic to fungi, such as 24,25-dihydrolanosterol (DHL), producing 4,4-dimethyl-8,14-cholestadien-3-beta-ol, but at lower rates than the endogenous substrates (By similarity).
What are the official names of this protein?
Lanosterol 14-alpha demethylase, CYPLI, Cytochrome P450 51, Cytochrome P450-14DM, Cytochrome P450-LIA1, Sterol 14-alpha demethylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane.
Protein: DOIS_STRKN
Sequence: MQVTTITMDDVQYPYRLGTDCLDGIVTRLGELGASRYLIVSDPRVAELYGQGLRERLAEQAGPAELITHASGEQNKGLPALHDLAEEALRRGADRQSIVVALGGGVTGNIAGLLAALLFRGIRLVHVPTTVVAMLDSVLSLKQAVNAGVGKNLVGTFYQPVEVLADTAMLRTLPVREVRSGMCEVVKNSLAIRPSMIDQLSAGLRPDGRYPDDTMHWIIYESLAAKAQVTAYDKYERGEGLILEYGHTVGHAVEHSSQGAVPHGAAVALGMIAAAQVSHRAGWASAELVDLHRELVAKTGVARRIPSDIPLSAVRHRLSFDNKRGYLPASADTYPMVLLESPGKVLRSEGTVLTAAPRDLVDAVVDELAEPPRPAAARTDDAATVLGGAG
What is the function of this protein?
Catalyzes the intramolecular carbocycle formation from D-glucose-6-phosphate to 2-deoxy-scyllo-inosose (DOI).
What are the official names of this protein?
2-deoxy-scyllo-inosose synthase, DOI synthase, DOIS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. DOI synthase family.
Protein: STPG1_DANRE
Sequence: MGKLHRGLAEFNGCASSIPPKYQTVIISNEEKKGFSSQSRRFEEYLNESPGPGSYLSHSPAEGCSPSFSKRGTGSFASKGGRVPRSFQRLSPGPDAYNLQMSLLHKHDFNRGESRIFRLPYALKKEKPNNENPAPNQYDVSYRAVDKNSTISGESAFRSKTRRSAVVSDKFKGPSPCHYKVSDVLVQKSPQALVSCFKSKTARIQSPVRNNIPGPGTYNPHQPPEPVKRTVLPRRYYLGLSAPPLIPEKVPPFPGPGHYDIVNYNRPVKHMVSSAAFLSGTNRHMQEVKGQDIPGPGFYEPTVLSKTSFLYNPAKLWIPA
What is the function of this protein?
May positively contribute to the induction of apoptosis triggered by O(6)-methylguanine.
What are the official names of this protein?
O(6)-methylguanine-induced apoptosis 2, MAPO2, Sperm-tail PG-rich repeat-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the STPG1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RLMH_SHEB2
Sequence: MKLQLIAVGTRMPDWVTRGFEEYQRRFPRDMALELIEIPAGKRGKNADIVRILQKEGEQMLAAIPKGNHIVSLDLPGKNWTTPELATALTKWQLDGRDVSLLIGGPEGLAPACKEAANQSWCLSALTLPHPLVRVVVAESLYRAWSVNTNHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CORO7_PONAB
Sequence: MNRFRVSKFRHTEARPPRREAWLSDIRAGTAPSCRNHIKSSCSLITFNSDRPGVLGIVPLQGQGEDKRRVAHLGCHSDLVTDLDFSPFDDFLLATGSADRTVKLWRLPGPGQALPSAPGVVLGPEDLPVEVLQFHPTSDGILVSAAGTTVKVWDAAKQQPLTELEAHGDLVQSAVWSRDGALVGTACKDKQLRIFDPRTKPQASQSTQAHENSRDSRLAWTGTWEHFVSTGFNQMREHEVKLWDTRFFSSALASLTLDTSLGCLMPLLDPDSGLLVLAGKGKRQLYCYEVVPQQPALSPVTQCVLESVLRGAALVPRQALAVMSCEVLRVLQLSDTAIVPIGYHVPRKAVEFHEDLFPDTAGCVPATDPHSWWAGDNQQAQKVSLNPACRPHPSFTSCLVPPTEPLPDTAQPAVTETPVGDADASEGFSSPPSSLTSPSTPSSLGPTLSSTSGIGTGPSLRSLQSLLGPSSKFRHAQGTVLHRDSHITNLKGLNLTTPGESDGFCANKLRVAVPLLSSGGQVAVLELRKPGRLPDTALPTLQNGAAVTDLAWDPFDPHRLAVAGEDARIRLWRVPAEGLEEVLTVPETVLTGHMEKICSLRFHPLAADVLASSSYDLTVRIWDLQAGVDRLKLQGHQDQIFSLAWSPDGQQLATVCKDGRVRVYRPRSGPEPLQEGPGPKGGRGARIVWVCDGRCLLVSGFDSQSERQLLLYEAEALAGGPLAVLGLDVAPSTLVPSYEPRHWPGAPDWQGDARVFLYELLPESPFFMECNSFTSPDPHKGFVLLPKTECDVREVELMRCLRCASPPWSLWPSGCPESGKSSFQDDVFPDTAVSWEPVLSAEAWLQGANGQPWLLSLQPPDMSPVSQAPREAPARRAPSSAQYLEEKSDQQKKEELLNAMVAKLGNREDPLPQDSFEGVDEDEWD
What is the function of this protein?
F-actin regulator involved in anterograde Golgi to endosome transport: upon ubiquitination via 'Lys-33'-linked ubiquitin chains by the BCR(KLHL20) E3 ubiquitin ligase complex, interacts with EPS15 and localizes to the trans-Golgi network, where it promotes actin polymerization, thereby facilitating post-Golgi trafficking.  May play a role in the maintenance of the Golgi apparatus morphology (By similarity).
What are the official names of this protein?
Coronin-7, Crn7.
What is the protein family that this protein belongs to?
Belongs to the WD repeat coronin family.
What are the subcellular locations of this protein?
Golgi apparatus membrane. Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle. Cytoplasm, cytosol. Note=Predominantly cytosolic. Detected on vesicle-like cytoplasmic structures and on the cis-Golgi. Not associated with actin filaments (By similarity).
Protein: PRB4_HUMAN
Sequence: MLLILLSVALLALSSAESSSEDVSQEESLFLISGKPEGRRPQGGNQPQRPPPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQSQGPPPHPGKPESRPPQGGHQSQGPPPTPGKPEGPPPQGGNQSQGTPPPPGKPEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPGKPQGPPPAGGNPQQPQAPPAGKPQGPPPPPQGGRPPRPAQGQQPPQ
What are the official names of this protein?
Basic salivary proline-rich protein 4, Salivary proline-rich protein Po, Parotid o protein, Salivary proline-rich protein II-1.
What are the subcellular locations of this protein?
Secreted.
Protein: FAN1_AILME
Sequence: MSEGKSPAKKRARRSLSISKTKKNECNSIISFFNNVPPAKLACPICSKMVPRYDLNWHLDEKCANNDNITPVDLRHVGFTDSSGSTVNLTNTVLENVTPGKLSPSKASLTPDPSDSAKMGIKQQTSPYFKNNKDLVFKNQDKLRHHNVKVITLGSLSSKLSRRYTEARRSICKKNEEFASKSPQSPSSTVVRSPVDNCSEIEDKDQILENSSQKENVFTCDSLNEQRTEHSVEDTKVLEAESQEATQECGRSPLTPAFSDNAFVLFSPDLTRGNPLRSTSEDSLEWETITGIDGKDVEKCEAGSCEEVKVTVASEAKTQLSDWEAKCHSSTPDDSKGCNIQDLLLEGDSDLKNEITCRIPLEQGSSCDVPDKTVTVPPSHPYYLRSFLVVLKAVFENEEDRMLFDEHEKEIVTKFYQLSASAQKLYVRLFQRKFSWLKMNKLEYEEIAPDLTPVIGELQQAGFLQTESELQELSEVLELLSAPELKTLAKTFHLVNPNGQKQQLVDTFLKLAKQPSVCTWGKNQPGIGAVILKRAKGLAGQALRVCKGPRAVFSRVLLLFSLTDSLEDEEAACGGQGQLSTVLLVNLGRMEFPRYTINRKTQIFQDRDDLIRYAAAAHMLSDISTAMANGNWKEANELSQCAKSDWNKLKSHPSLRYHENLPLFLRCFTVGWIYTRILSRTVEILQRLHMYEEAVKELESLLSQRVYCPDSRGRWWDRLALNLHQHLKRLEPAIKCITEGLADPEVRTGHRLSLYQRALRLRESPSCQKYRHLFHQLPEVTVGDVKHVTITGRLCPQRGMGKSVFVMEAGGPTAPATVLCSVEEVALAYYRRSGFDQGIHGEGSTFSTLYGLLLWDIIFMDGIPDVFRNAYQASPLDLCTDSFFASRGPAIEARLQRIHSAPAESLRAWVAAAWQAQEGRVASIVSWDRFASLQQAQDLVSCLGGPVLSGVCRRLAADFRHCRGGLPDLVVWNSQSRHFKLVEVKGPNDRLSHKQMLWLDELQKLGADVEVCHVVAVGAKSKSLT
What is the function of this protein?
Nuclease required for the repair of DNA interstrand cross-links (ICL) recruited at sites of DNA damage by monoubiquitinated FANCD2.  Specifically involved in repair of ICL-induced DNA breaks by being required for efficient homologous recombination, probably in the resolution of homologous recombination intermediates.  Not involved in DNA double-strand breaks resection.  Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.  Probably keeps excising with 3'-flap annealing until it reaches and unhooks the ICL.  Acts at sites that have a 5'-terminal phosphate anchor at a nick or a 1- or 2-nucleotide flap and is augmented by a 3' flap.  Also has endonuclease activity toward 5'-flaps.
What are the official names of this protein?
Fanconi-associated nuclease 1, FANCD2/FANCI-associated nuclease 1, Myotubularin-related protein 15.
What is the protein family that this protein belongs to?
Belongs to the FAN1 family.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes at sites of DNA damage following recruitment by monoubiquitinated FANCD2. Localizes to stalled replication forks via its UBZ4-type zinc finger.
Protein: RS22B_YEAST
Sequence: MTRSSVLADALNAINNAEKTGKRQVLLRPSSKVIIKFLQVMQKHGYIGEFEYIDDHRSGKIVVQLNGRLNKCGVISPRFNVKIGDIEKWTANLLPARQFGYVILTTSAGIMDHEEARRKHVSGKILGFVY
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
40S ribosomal protein S22-B, RP50, S24, Small ribosomal subunit protein uS8-B, YP58, YS22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDHI_HELAN
Sequence: MFPMVTEFMNYGQQTVRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSIIDDYTIRTILNLPEIKT
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: MURG_LEPBJ
Sequence: MRSIVIAAGGTGGHISPGVALAEVLTDLKEKIGYENLYLYSLIRNQNNPDLEQAPCPVLWHNLPPLSSNIFLFPFRYTIQILKTFLLFKKLNVDVVIGMGGYSTVSSILYGILFKKKIYLCEQNTVPGNVSRLFFRFANKAAFSFPPKNSAIPCDYQVLGNPLRKKTLPKMSLKFSEKYDTKKKTQFNVLVMGGSQGARQINNIVIALMGHEEINIQFRFRVLTGSALYEEVSKKTKKDAELISYSDNMKEHYEWANFVIARAGSGVLSECAAFALPMILIPYPYAKDDHQMANARYLELNGAAIVIDQKDEDESHLFKVLDQIANNVNLLNDMSISSLQCSHVDASKDTVKYFFSLD
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CAST1_BOVIN
Sequence: MELHILEHRVRVLSLARPGLWLYTHPLIKLLFLPRRSRCKFFSLTETPEDYTLMVDEEGFKELPPSEFLQVAEATWLVLNVSSPSGAAVQAAGVTKIARSVIAPLAEHHVSVLMLSTYQTDFILVREQDLSVVIHTLAREFDIYREVGGEPVPVARDDSSNGFPRAQHGPSPTVHPIQSPQNRFCVLTLDPETLPAIATTLIDVLFYSHSPPREAASGGPGSSSIAFFAFSLIEGYISIVMDAETQKKFPSDLLLTSSSGELWRMVRIGGQPLGFDECGIVAQIAGPLAAADISAYYISTFNFDHALVPEDGIGSVIEVLQRRQDGLGS
What is the function of this protein?
Functions as an intracellular arginine sensor within the amino acid-sensing branch of the TORC1 signaling pathway.  As a homodimer or a heterodimer with CASTOR2, binds and inhibits the GATOR subcomplex GATOR2 and thereby mTORC1.  Binding of arginine to CASTOR1 allosterically disrupts the interaction of CASTOR1-containing dimers with GATOR2 which can in turn activate mTORC1 and the TORC1 signaling pathway.
What are the official names of this protein?
Cytosolic arginine sensor for mTORC1 subunit 1, GATS-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the GATS family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: MURB_FUSNN
Sequence: MKIFTNQEMKNYSNMRVGGKAKKLIILEPKEEIIDVYNDKENTDIFILGNGTNILFTDEYMDKIFVCTKKLNKIEDLGKNLVKVETGANLKDLTDFMKDKNYTGIESLFGIPGSIGGLVYMNGGAFGTEIFDKIVSIEVFDENHQIREIKKEDLKVAYRKTEIQDKNWLVLSATFKFDNGFDAARVKEIKELRESKHPLDKPSLGSTFKNPEGDFAARLISECGLKGTIIGNAQIAEKHPNFVLNLGNATFKDIIDILTLVKKSVLEKFGIKLEEEIIIVR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_ACTP2
Sequence: MQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLISPHVNKDARDQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLG
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RHAB_ECO55
Sequence: MTFRNCVAVDLGASSGRVMLARYQRECRSLTLREIHRFKNGLHSQNGYVTWNVDSLESAIRLGLNKVCEEGIRIDSIGIDTWGVDFVLLDQQGQRVGLPVAYRDSRSNGLMAQAQQQLGKRDIYQRSGIQFLPFNTLYQLRALTEQQPELIPHIAHALLMPDYFSYRLTGKMNWEYTNATTTQLVNINSDDWDESLLAWSGANKAWFGRPTHPGNVIGHWICPQGNEIPVVAVASHDTASAVIASPLNGSRAAYLSSGTWSLMGFESQTPFTNDTALAANITNEGGAEGRYRVLKNIMGLWLLQRVLQERQINDLPALIAATQALPACRFIINPNDDRFINPEAMCSEIQAACRETAQPIPESDAELARCIFDSLALLYADVLHELAQLRGEDFSQLHIVGGGCQNTLLNQLCADACGIRVIAGPVEASTLGNIGIQLMTLDELNNVDDFRQVVSTTANLTTFTPNPDSEIAHYVAQIHSTRQTKELCA
What is the function of this protein?
Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose).  Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate.
What are the official names of this protein?
Rhamnulokinase, RhaB, ATP:L-rhamnulose phosphotransferase, L-rhamnulose 1-kinase, Rhamnulose kinase.
What is the protein family that this protein belongs to?
Belongs to the rhamnulokinase family.
Protein: KGUA_CUPMC
Sequence: MSETTHTAIDTAYPGNLFMVVAPSGAGKSTLVNALLAQDKAIRLSISHTTRSPRPGEQNGREYHFISVDEFRAARDRGEFLEWAEVHGNYYATSRVWIEEQMAQGTDVLLEIDWQGAQQVHKRFSNAVEIFILPPSLTALEERLKKRGQDEPNVIVRRLLAAGSEMSHASESDYVIINEVFDDALKQLQNVVHATRLRFSSQKARHAELFIELGIH
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SIX3C_LEIHE
Sequence: MKLLLLLTISASMLIEGLVNADGYIRGGDGCKVSCVINHVFCDNECKAAGGSYGYCWAWGLACWCEGLPAEREWDYETNTCGGKK
What is the function of this protein?
Depressant insect beta-toxins cause a transient contraction paralysis followed by a slow flaccid paralysis.  They bind voltage-independently at site-4 of sodium channels (Nav) and block action potentials, primarily by depolarizing the axonal membrane and suppressing the sodium current.  This depressant toxin is active only on insects.  It is found in a relatively small amount in the venom, and its activity on insects is 10-fold higher compared to other known depressant toxins.
What are the official names of this protein?
Beta-insect depressant toxin Lqh-dprIT3c.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GLPB_ALIF1
Sequence: MNFDTIIIGGGMAGLSCALRCLEAGLKTAVIASGQSALHFSSGSIDVLAKTPSGKHVINPMDSLETFSKEYPSHPYAALGKETVERAINWYKTTLSAIGVPLTSQKDGLNHYRLTPLGTMKSTWLSQPFVHQFPMDLEKNKTQKMVLITIDGFRDFQPKLAQDNLKQITQLSDLEIATASISLSAFNDIQRNHCELRSIDISRLLSKRANRQELAYALQQHANPGDLVVLPSIFGNGTGLSYLREIEQLTKLTLCEVPTMPPSLLGIRLEESMKHAFIELGGTMLNGDHVVQGEFSYVDKSDPEHSHYRLNRLFTKNHGDFPLQAKQFVLATGSFFSQGLKANVDSMIEPIFGLDIAQSDKRTDWYSHDFFSTQSHPFLSMGIKTTANFQAIKSGHVIDNLYCAGAILSGYNPILEGSGSGVAISSGFHAAESIIEQLQCSDSLQNNNTKAEVAL
What is the function of this protein?
Conversion of glycerol 3-phosphate to dihydroxyacetone.  Uses fumarate or nitrate as electron acceptor.
What are the official names of this protein?
Anaerobic glycerol-3-phosphate dehydrogenase subunit B, Anaerobic G-3-P dehydrogenase subunit B, Anaerobic G3Pdhase B.
What is the protein family that this protein belongs to?
Belongs to the anaerobic G-3-P dehydrogenase subunit B family.