PharMolix/UniProtQA huggingface dataset:
Protein: RL31B_OENOB
Sequence: MKADIHPDYRQVVFVDSTTGAKFLSGSTAKAQGEVEYEGQTYPMVRVEVTSDSHPFYTGKQKINQADGAVDKFNKKYGLN
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: PSIR_PSICU
Sequence: MAPATPATHDPALSHGAPPAPGAPAPANAPPNASGDIAGMQLSGLDQSQIMNLLRSLPGMFSGGKIPDQGQGNKEDAAQTLSNLAQAQPYGQQLPLHYQAGGPGGLPGINDPGPSTHPRGPPNLGQLSAVAMQAAPAPIQHPDQQTNRNDGEQAGNASASTSGKDGDNAEFVPPPAPAPTTGRRGGRSATMGSDEWSRQRKDNHKEVERRRRGNINEGINELGRIVPSGSGEKAKGAILSRAVQYIHHLKENEARNIEKWTLEKLLMDQAMGDLQAQLEEVKRLWEEERMARTRLEAELEVLRNMNGVNAGSAPASKDESAAGTKRRSTDGAEAATAATESSTANAEGERDGKRQRTE
What is the function of this protein?
Transcription factor that may regulate the expression of the gene cluster that mediates the biosynthesis of psilocybin, a psychotropic tryptamine-derived natural product (PubMed:28763571).
What are the official names of this protein?
Psilocybin cluster transcription regulator.
What are the subcellular locations of this protein?
Nucleus.
Protein: TXG4A_ETHRU
Sequence: MNTVSVVQFLAVGCAVFVLYGRGVFAAEGVKKAGQHKDAELCLGSDGLGHRLDEFWYNDDMCQRFLCFKDDEGIMYEQIANCPIAIAEGDCTLKPGTKGHYPDCSPRRRIAPLRTKKKGKFKRNAFYLPY
What are the official names of this protein?
U-scoloptoxin(16)-Er4a, U-SLPTX(16)-Er4a.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-16 family.
What are the subcellular locations of this protein?
Secreted.
Protein: HLYA_AERHY
Sequence: MASALSPGSRVLIALIRVYQRLISPLLGPHCRFTPTCSSYGIEALRRFGVIKGSWLTVKRVLKCHPLHPGGDDPVPPGPFDTREH
What is the function of this protein?
Lyses fish blood cells.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor, Putative alpha-hemolysin.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y4549_CITK8
Sequence: MTPWYLYLIRTADNALYTGITTDVARRYKQHQSGKGAKALRGKGELTLAFSAQVGERSLALRMEYRIKRLTKRQKERLVTEGEGFEALLASLQTPTLKSD
What are the official names of this protein?
UPF0213 protein CKO_04549.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: DPOG_SCHPO
Sequence: MFYKACPSTLTCSKWIHSIIKTKKFLYCRHYSSKSFIDNAPLRINPVGVQYLSPALQNQVFPQQNTQISQLHLDLAKFHLAKHQLLNKETIKLPSFNFRLPPLQGKTISEHFYNIGLEFAEPHLSKAIKFSKIDTPVQPKTWKRQPGWTKYAKDGSISCVPYPDSDCMVFDVEVLYKVSPFAVVATAVSEDAWYCWLSPWLLGKSENDRQLIPSNPKGALFVGHNVSFDRQRIREEYNIKSSRNVFLDTMSLHVATHGMCSRQKPTWFKARKAYIRSQSTETSEDDDSSSFDDDYQNYLKQEPWLAHSSVNSLKDVAKFHCNITLDKSKRDDFASLEKEPILQKLNELITYCAHDTYSTHQVFKKVFPQFLEVCPHPATFSAMLSLGSVFLPVNHSWTRYINGVEEQYQQMIQLVDQKLSQYAEKAKDLINTKDTVLKDPWLRQLDWTPCNLYRKLKKATQEVPVVPKWYKKAYCKTEKRAVITAKSRLAPILLRLKWKKHPLAWSDTYGWVFSVERTSKDEIEMLLDQGLVPCSREEDTKLDYNNYIFFKVPHKDGPEARCGSPLSKSYQRYFEEGILQSDYEVAKKALEMSASCSYWSSARDRIRSQMVVWDKDAELGVPSSVDGFGIILPCIIPMGTVTRRAVENTWLTASNSKKNRLGSELKAMIRAPDGYTFVGADVDSEELWIVALMGDSQFRLHGATALGMMTLEGKKSEGTDLHSKTAAILGVSRDSAKVFNYGRLYGAGLKHTTLLLMQMNPTLKTAEAKELAKKLYASTKGVKSKMSKRLQEMGLPKLTFWSQGTESFVFNKLEAMAQLPSPRTPVLDAGITQALSSKNLSKNSFMTSRVNWAIQSSAVDYLHLLLVSMNHLIKKYYLEARLSLTVHDEVRYLSSDKDKYRVAFALQVANLWTRAFFCQRLGINELPQSVAFFSSVDIDHVLRKDVKMDCVTPSNKVPIPPGEELTIESVLEKLEQSGQSLEPLEQIQCFVDVKATTSAEITEEDKKNIAYLKAQAFY
What is the function of this protein?
Involved in the replication of mitochondrial DNA.
What are the official names of this protein?
DNA polymerase gamma, Mitochondrial DNA polymerase catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-A family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CCP11_ORYSJ
Sequence: MDAAAAAGGEMSRQKATASAPPPPELDMVARAVQRLVARNDAVEALSGGGEAAAGLGAGMAAFEAARGAPAPRIGVAQYLERVHRYAGLEPECYVVAYAYVDMAAHRRPAAAVASRNVHRLLLACLLVASKVLDDFHHNNAFFARVGGVSNAEMNRLELELLAVLDFEVMLSHRVYELYREHLEKEARRDGGGGDMLAGASAAAAAKAGRMAAVSPSKLLERAAVNGAAQHDDWRSLGTAAAAEAANGVRRHRSSSSSRYSFDC
What are the official names of this protein?
Cyclin-P1-1, CycP1;1.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin U/P subfamily.
Protein: RS13_SINMW
Sequence: MARIAGVNIPTAKRVVIALTYIHGIGTKFAQEIVEKVGIPAERRVHQLTDAEVLQIRETIDRDYQVEGDLRRETSMNIKRLMDLGCYRGLRHRRGLPVRGQRTHTNARTRKGPAKAIAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: GGI3_STAHJ
Sequence: MSKLVQAISDAVQAGQNQDWAKLGTSIVGIVENGVGILGKLFGF
What is the function of this protein?
Has hemolytic activity and also inhibits the growth of gonococci.
What are the official names of this protein?
Antibacterial protein 3 homolog.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal hemolytic protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: AP4AH_STAA8
Sequence: MNIEKAKRLAKEKLPEKRYNHSLRVAETAIKLAEIYDGDTSKVELAGVLHDFCKYDDLGKMYQIVRQYELGNDLLSYGSEILHGPVCAAIMEHEYGINDEEVLMAIKYHTTGRQQMTKTEKLIFIADYIEPGRTIPGVDDIRDMAYNQGSLDKTIYEISKRTVLFLIQKDITVYNKTIDCLNYYNYSDERIKDD
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate (Ap4A) to yield ADP (PubMed:32152217).  Can also hydrolyze Ap3A, Ap5A, Ap4G, Ap4U and Gp4G, always releasing ADP or GDP as one of the products, but it exhibits a marked preference for Ap4A, which is mainly exerted at the substrate affinity level (PubMed:32152217).
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Symmetrically cleaving Ap4A hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase YqeK family.
Protein: BCAS3_DROME
Sequence: MSADSPRRHPSGVVGSGIGLGSGSGTGLGSGSTGGSKSGAAVPAIVPPQTVSDRSILDSAIGFINDVTLANQPVQDPKDTITWARFETCADVSDPRFGDDWELEGNAAPPLLLILGYGLGVQVWAIPANGEAVEVLSWRHGVVTALRVLPTPATAAALDENGRADEPVDSFAEKRPLVAFVDGGSAAASGLLAGSSGLGLGGGGGGVTTVGGSVGGVSGIGVSASAQFSAVNFMSLKTGVQVKTIKFKNAVLDIQANRSAVVITFHERIAVFDARTLEDRLTITTCYPSPGINPNPIALGPRWLAYAEHKLLHSKRSGGGCDGEGVPSYTATVLNAAKSLSKGLREFGEQVAAGLTGTTAGSGASSKSSSFDSASGGPDAKQSGVVTIIDVKHPVKDYSPTSGTPLSSTAGSQGGGDPIVAHFVAHSEALVAMEFDSSGMLLLTADRRGHDFHVFRVQPHPVGPSLAAVHHLYVLHRGDTSAKVQHIAFSLDSRWAAVSTLRGTTHVFPITPYGGAMGVRTHTSLHVVNKLSRFHRSAGLGADGRSSSPISHSESTTFVQSLQPYHNPTLPPYPRPSVVQPLAQLRQPFTLGSPPGSAGLGGGVGGGGVMGSGVSAGGHGVGVGVGSNSQRQRQRLSSLSDDSGKPLSVCSIFAKSRSWLLEPPMATREQPHRVQRKAVDSLFVMAGHGALIQYDLDTKLASHVAKEKICDDTPIELEVEARAQWNLGRRKDGSQEIAPPLGLDNWLIKDRHASLLLDSANQFDDPDERTESWLAQVEIITHAGPHRRLWMGPQFVFKNYNTPSGSNLNHVDAEAVEIGVSKTTTTTLPSTAASSALGLGTIIGKDRSSPLNMPLSAATSVGGAGIGSSAVTGRSGAGVPVLIESGSYSSIEQSPKLMDRFRHGHLDSDYGHGDTRLKEDLADAMRESPSTAAARRETTGNYFTTDQLDGLALNNNNNINNNIIPTKDNASPNPNTNTNPNAIPSSNKVQKAEVTDAVDYPIRHSYGDHGELSTVVNIEVFDDQLSMSSISTNSRLSLEGPPSQSSPPLSLTNGLMDTNLMHFSESVTGTGVAQAQVHGRGANRFEVDDDDEEEEEEEEELDEEAEPDDDEREDRPLGRRNL
What is the function of this protein?
Regulates macropinocytosis in pericardial cells.
What are the official names of this protein?
Breast carcinoma-amplified sequence 3 homolog, Protein rudhira, DRudh.
What is the protein family that this protein belongs to?
Belongs to the BCAS3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FES1_CANGA
Sequence: MEKLLHWSIANAQGDKEAIEKAGAPDPKLLEQLFGGGGPDDPTLMKEAMAVIMNPEADLENKLIAYDNFEMLIENLDNANNIENMKLWEPILKTLEDNEADLRASGLSVIGTAVQNNTDSQTNFLKYEGGLKILIAIAKSSEEPSDVRIKAFYALSNLLRNHIEAGKKFQALGGLDVFPVALNDPKATPKLKMRAISALSAFLSSSKIDEQLLDTLRKDGVLVSVIENLGTDNVNVIDRVLSVLSHLISSGIKFNDSELEMLQKEFEKIDSLKDRLNEDDYLAVKYVFSKK
What is the function of this protein?
Functions as a nucleotide exchange factor (NEF) for Hsp70 chaperones which accelerates the release of ADP.  Required for fully efficient Hsp70-mediated folding of proteins (By similarity).
What are the official names of this protein?
Hsp70 nucleotide exchange factor FES1.
What is the protein family that this protein belongs to?
Belongs to the FES1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LCB5_YEAST
Sequence: MTLKPSKRRKGRSRHSRKKQITSAILTEEGIMIKAKPSSPYTYANRMADKRSRSSIDNISRTSFQSNISRTSFQSNSDNNSIFETASLISCVTCLSDTDTIDRSETSTTDTSKDDLSANPKLHYPSVNGQLPANTVIPYGRILDARYIEKEPLHYYDANSSPSSPLSSSMSNISEKCDLDELESSQKKERKGNSLSRGSNSSSSLLTSRSPFTKLVEVIFARPRRHDVVPKRVSLYIDYKPHSSSHLKEEDDLVEEILKRSYKNTRRNKSIFVIINPFGGKGKAKKLFMTKAKPLLLASRCSIEVVYTKYPGHAIEIAREMDIDKYDTIACASGDGIPHEVINGLYQRPDHVKAFNNIAITEIPCGSGNAMSVSCHWTNNPSYSTLCLIKSIETRIDLMCCSQPSYAREHPKLSFLSQTYGLIAETDINTEFIRWMGPARFELGVAFNIIQKKKYPCEIYVKYAAKSKNELKNHYLEHKNKGSLEFQHITMNKDNEDCDNYNYENEYETENEDEDEDADADDEDSHLISRDLADSSADQIKEEDFKIKYPLDEGIPSDWERLDPNISNNLGIFYTGKMPYVAADTKFFPAALPSDGTMDMVITDARTSLTRMAPILLGLDKGSHVLQPEVLHSKILAYKIIPKLGNGLFSVDGEKFPLEPLQVEIMPRLCKTLLRNGRYVDTDFDSM
What is the function of this protein?
Catalyzes the phosphorylation of the sphingoid long chain bases dihydrosphingosine (DHS or sphinganine) and phytosphingosine (PHS) to form dihydrosphingosine 1-phosphate (DHS-1P) and phytosphingosine 1-phosphate (PHS-1P) respectively (PubMed:9677363, PubMed:11102354, PubMed:12493772, PubMed:25345524).  Redundant to LCB4, is only responsible for few percent of the total activity (PubMed:9677363).  Involved in the biosynthesis of sphingolipids and ceramides (PubMed:9677363, PubMed:25345524).  Involved in heat-induced transient cell cycle arrest (PubMed:11056159).  Accumulation of phosphorylated sphingoid long chain bases (LCBPs) stimulates calcium influx and activates calcineurin signaling (PubMed:11102354, PubMed:11278643).  Involved in heat-stress resistance (PubMed:11056159).
What are the official names of this protein?
Sphingoid long chain base kinase 5, LCB kinase 5, Sphinganine kinase 5.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein.
Protein: UREG2_METEP
Sequence: MKKITRIGIGGPVGSGKTAVIETITPRLIALGIKPLIITNDVVTTEDAKQVRRTLHGVLIEEKIVGVETGACPHTAVREDPSMNIAAVEELEDKYPDSDVILIESGGDNLTLTFSPALADFYIYVIDVAAGDKIPRKNGAGVCQSDILVINKKDLAPYVGASLEVMARDSKLMRGKKPFLFTNCKTGEGVDDLLQLILDMALFDVRTRPPLAASA
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG 2.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COQ7_PSEPG
Sequence: MATERHYSPLDRLLLQADTAMRTLLPFSGQPARPSPAIIQPDADLDEQQSRHIAGLMRINHTGEVCAQALYQGQALTAKLPEVRKAMEHAAEEEIDHLAWCEQRIRQLNSHPSVLNPLFYGMSFGIGALAGLVSDKVSLGFVAATEHQVCKHLDEHLEQIPHEDEKSRAILEQMRIDEEQHAESALEAGGYRFPAPVRFGMSLLAKVMTKSTYRI
What is the function of this protein?
Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
What are the official names of this protein?
3-demethoxyubiquinol 3-hydroxylase, DMQ hydroxylase, 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the COQ7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL10A_MACFA
Sequence: MSSKVSRDTLYEAVREVLHGNQRKRRKFLETVELQISLKNYDPQKDKRFSGTVRLKSTPRPKFSVCVLGDQQHCDEAKAVDIPHMDIEALKKLNKNKKLVKKLAKKYDAFLASESLIKQIPRILGPGLNKAGKFPSPLTHNENMVAKVDEVKSTIKFQMKRVLCLAVAVGHVKMTDDELVYNIHLAVNFLVSLLKKNWQNVRALYIKSTMGKPQRLY
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L10a.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MPKC_ASPOR
Sequence: MEFIRAEILGTTFETTSRYANVQPVGLGAFGLVCSAYDQITQQHVAVKKMMNPFANASIAKRTYREVKLLKQLRHENLIGLCDIFISPLEDIYLVTELLGTDLGRLLRARPLDNKFAQYFMYQILRGLKYIHSAGVIHRDLKPSNLLVNENCDLKICDFGLARVQEPQMTGYVSTRYYRAPEIMLTWQRYGKMVDIWSAGCILAEMLRGKPLFPGKDHIHQFFLITEVLGNPPPEVVQKITSGNTQRVVNSLPNQEPRPLRAVFHEFDNDVISLLEQLLLFDPDKRLTAETALQHPYLAPYHDPDDEPAALEKFDWSFNDADLPIDTWKLMMCVAIGSAKCAPN
What is the function of this protein?
Mitogen-activated protein kinase required for growth on media where sorbitol or mannitol is the sole carbon source.
What are the official names of this protein?
Mitogen-activated protein kinase mpkC, MAP kinase C.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. HOG1 sub-subfamily.
Protein: QUEA_STRSV
Sequence: MNTADFDFDLPEELIAQTPLEKRDASRLLVVDKETGAFSDQHFDQIIDQLQPGDALVMNNTRVLPARLYGIKPETGGHVELLLLKNTQGDDWEVLAKPAKRLRVGAQISFGDGRLTATVIEELEHGGRIVRFSYEGIFLEVLESLGEMPLPPYIHEKLADRERYQTVYAKENGSAAAPTAGLHFTEELLEQIAAKGVKLVYLTLHVGLGTFRPVSVDSLDDHEMHSEFYSLSEEAAQTLRQVKANGGRVIAVGTTSIRTLETIGSKFQGQIQADSGWTNIFIKPGYNWKVVDAFSTNFHLPKSTLVMLVSAFAGRSLTLEAYEHAIAERYRFFSFGDAMFIK
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_BORPE
Sequence: MAQKQIKVTLVRSVIGTKQSHRDTIRGLGLRRINSSRVLVDTPEVRGMIHKVGYLVSVSEA
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: NDHL_PROM0
Sequence: MESIFNNSFATLIAYIGIISTYLLVIPLLLFYWMNNRWNIMGKFERLGIYGLVFLFFPGLILFSPFLNLRLKGTGKG
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit L, NAD(P)H dehydrogenase I subunit L, NDH-1 subunit L, NDH-L.
What is the protein family that this protein belongs to?
Belongs to the complex I NdhL subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: RL36_LARHH
Sequence: MRVQPSVKKICRNCKIIRRHGIVRVICTDPRHKQKQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: RL32_PROA2
Sequence: MATPKAKVSKSRRDKRRAQFTARSKAAVTTICPNCGEPTLSHRACRHCGQYRGRVVTKKSANG
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: CARA_METJA
Sequence: MEAVLILEDGTILKGKGFGAEKEVFGELVFTTVMTGYVEVLTDPSYKGQIVMMTYPLEGNYGVKKDWFESDGIKAEGFVVREVTSKALDDFLKEYDIPGIQDIDTRFLTRKIRDKGVVKSCLKVAEEISDDEISELLERVKRYSDISDIDLVPLVSTKEPKIHKTANPKARCVLIDCGVKLNIIRSLVQRNCEVIQVPYNTKYDEILEYKPDFVLISNGPGDPARLKEVIKNIKNLIGVVPITGICLGNQLLSLAFGGETYKMKFGHRGGNQPVKDLKTQKVYITSQNHGFAVRKESLPDDVEVSFINLNDMTVEGIRHKDLPIFSVQFHPEARPGPHDTMFLFDEMIKLKDRK
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: RL19_CHLPD
Sequence: MDQLIQLVEASEARNDFPAINPGDTVKIQLKVIEGEKERLQAFEGVVISDRGAGGSKTITVRKISHGVGVERIIPVNSPNIESITVLKHGKARRAKLFYLRKRTGKAALKVKARKVVEKA
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: PDXK_MOUSE
Sequence: MEGECRVLSIQSHVVRGYVGNRAAMFPLQVLGFEVDAVNSVQFSNHTGYAHWKGQVLKSQELHELYEGLKVNDVNKYDYVLTGYTRDKSFLAMVVDIVRELKQQNSRLVYVCDPVMGDKWNGEGSMYVPQDLLPVYRDKVVPVADIITPNQFEAELLSGRKIHSQEEAFEVMDMLHCMGPDTVVITSSDLPSSQGSDYLIALGSQRMRKPDGSTVTQRIRMEMRKVEAVFVGTGDLFAAMLLAWTHKHPDNLKVACEKTVSAMQHVLQRTIRCAKAEAGEGQKPSPAQLELRMVQSKRDIEDPEIVVQATVL
What is the function of this protein?
Catalyzes the phosphorylation of the dietary vitamin B6 vitamers pyridoxal (PL), pyridoxine (PN) and pyridoxamine (PM) to form pyridoxal 5'-phosphate (PLP), pyridoxine 5'-phosphate (PNP) and pyridoxamine 5'-phosphate (PMP), respectively (By similarity).  PLP is the active form of vitamin B6, and acts as a cofactor for over 140 different enzymatic reactions (By similarity).
What are the official names of this protein?
Pyridoxal kinase, Pyridoxine kinase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxine kinase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RF11_METAC
Sequence: MTEQSAHEKYEFKKKLESLRDKKGRSTELISLYIPADKQIFDVTNQLKDEHGQAANIKSKLTRTNVQGAIESLLSRLRYLDKVPENGIVYFTGAVDIGANKTSMESEVIIPPEPITVYKYHCDSSFYLEPLEDMLKDKSTFGLLVLDRREATIGLLVGKRIQAFRNLTSTVPGKQRKGGQSAHRFQQLRLIAIHDFYKRIGDAASEIFMAVDHKDLKGVLIGGPSPTKEEFYGGEFLHHELQKKILGLFDTAYTDESGLSELVNAAGEKLQDLELMGQKNAVRDFFKELIADSGKVAYGETQVRANLEINAVDVLLLSEDLRAERVTTKCSVCGYENKWTRRWKPGEPAPTAGNCPKCGSSLEVTDVIDVVDEFSELADKSNAKVVFVSTDFDEGSQLMNAFGGIAAILRYSTGV
What is the function of this protein?
Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
What are the official names of this protein?
Peptide chain release factor subunit 1-1, Translation termination factor aRF1 1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y405_EXISA
Sequence: MLAPGQLERINFLANKAKTEGLSQDEMNEQQNLRQEYLKAFRQSFKSQMMGMKVVDPDGNDVTPEKLKEDQKRYRGE
What are the official names of this protein?
UPF0291 protein EAT1b_0405.
What is the protein family that this protein belongs to?
Belongs to the UPF0291 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y115_ADE02
Sequence: MGETWFLTPNGQSSPGSWNARPSAGPAARMPTPRNRYFSRPSSTPLKVCTAPRAAPPPRASCAPRATPRRGWTMTPWSNATWPTRRAKTGSASAPAGPASSAPWPARSPERTPSP
What are the official names of this protein?
Uncharacterized protein E-115.
Protein: TRT2_ASPTN
Sequence: MPILAPLGPSPLSEVFTYSNLPSPVEMATGKDYRHSKAGILSKLPPSIKPYAELLRIHRPLGYYLNISPYVVGVAYTAAIAPVSLPATVLLNRLIILSLWGFLIRSGGCAWNDLIDMDIDRQVSRTKLRPLPRGAISPTSAALLTAIIFGCGGLLLLLLPSQCTVEAGIILFFALLYPFGKRFSDYPQLILVNIAWAIPMAMSSLEVDPLDFPYSTLSMCIFIASVIVMIDVVYACQDAEEDKKIGARSMAVRYSDITDQLAYGFFFSGAISLLLGGVLRGLGLPFIVFSVGGHIFGFLRFLSVTLGEGTKSASVESRAKSSCLLATVFWVLGFFLEYLARS
What is the function of this protein?
Polyprenyl transferase; part of the gene cluster that mediates the biosynthesis of terretonin, a fungal meroterpenoid that acts as a mycotoxin (PubMed:22549923, PubMed:23116177, PubMed:25671343).  The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid (DMOA) by the polyketide synthase trt4 (PubMed:22549923, PubMed:23116177).  DMOA is then prenylated into farnesyl-DMOA by the polyprenyl transferase trt2 (PubMed:22549923, PubMed:22782788, PubMed:23116177).  Methylation by the methyltransferase trt5 then leads to farnesyl-DMOA methyl ester which is further subject to epoxidation by the FAD-dependent monooxygenase trt8 to yield epoxyfarnesyl-DMOA methyl ester (PubMed:22549923, PubMed:22782788, PubMed:23116177).  Cyclization of epoxyfarnesyl-DMOA methyl ester by the terpene cyclase trt1 leads to a tetracycle intermediate which is in turn converted to preterretonin (PubMed:22549923, PubMed:22782788, PubMed:23116177).  Dehydrogenase trt9 comes next to transform preterretonin to preterrenoid (PubMed:22549923, PubMed:23116177).  The FAD-dependent monooxygenase trt3 is then required for the C-hydroxylation at C16 of preterrenoid to yield terrenoid (PubMed:22549923, PubMed:23116177).  The cytochrome P450 trt6 catalyzes three successive oxidations to transform terrenoid into an unstable intermediate, which then undergoes the D-ring expansion and unusual rearrangement of the methoxy group to afford the core skeleton of terretonin (PubMed:25671343, PubMed:28759016).  Trt14 catalyzes the D-ring expansion of terretonin involving intramolecular methoxy rearrangement as well as the hydrolysis of the expanded D-ring and the methyl ester moiety (PubMed:25671343, PubMed:28759016).  Finally, the nonheme iron-dependent dioxygenase trt7 accomplishes the last two oxidation reactions steps to complete the biosynthesis of terretonin (PubMed:25671343).  Terretonin C is produced via spontaneous decarboxylation of the terretonin precursor (PubMed:23116177).  Another shunt product of the terretonin biosynthesis is dihydrofarnesyl-DMOA, derived from epoxyfarnesyl-DMOA through hydrolysis of the epoxide (PubMed:22549923, PubMed:22782788, PubMed:23116177).
What are the official names of this protein?
Polyprenyl transferase trt2, Terretonin synthesis protein 2.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL25_METSB
Sequence: MAETKTLAAAARHGTGKGAARSVRREGRIPGVIYGGGDPAEPITLDYRELNKLIYAGHFLTTLFEIDVAGTKQRVIPRDYQLDPIKDLPLHVDFLRLKPGASLKVEVPVHFLNQETCPGVKKGGSVNIVRHSIELRVPADDIPEAITADLGELEINDSLHLTALALPQGCRPTQRERDFTIVTITPPLVVAETPVAAAAAAAAPKGKAGAKAAPAAAAAPAAPAKKK
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: GPMA1_NITEU
Sequence: MNEIQEPIRLVLLRHGQSIWNQDRHFTGWGDIVLSPQGEQEALRAGHLLKQAGFTFDACFCSELQRASDTLAIVQSVMGLNHLSTYRTWRLNERHYGALEGMRPWAAIRKFGIWSTMKSQIRFDAAPPLLMPDDPRAPVNQPRYAAVDRTQLPLAESMQQTLERVRPLWQETILPEIRQGKRLLIVSHQNLLKTLVMQLEGLTGAQIMRLSITTGHPLCYELDHSLVPVKRYYL
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 1, BPG-dependent PGAM 1, PGAM 1, Phosphoglyceromutase 1, dPGM 1.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: RPO12_THEON
Sequence: MVMAVYRCAKCGKEVELDLENTREVRCPYCGSKILYKPRPRVARRVKAI
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo12, DNA-directed RNA polymerase subunit P.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.