PharMolix/UniProtQA huggingface dataset:
Protein: NDUA3_NEUCR
Sequence: MSGTIPHFWAQPFRYIRWSAREKPAYFYSCVIAGLGPVFLTVVPPVRKYFGDVNPAPIPVTYPIPTGPRKQLTGYDDDTEEA
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.  This subunit binds ubiquinone.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase 9.5 kDa subunit, Complex I-9.5kD, CI-9.5, Ubiquinone-binding protein.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFA3 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: PSBI_THEVB
Sequence: METLKITVYIVVTFFVLLFVFGFLSGDPARNPKRKDLE
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  May be required for formation of PSII dimers but not their subsequent stability (PubMed:21195048).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.4 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: COLUA_COLDE
Sequence: VISIIPV
What is the function of this protein?
Has antifungal activity against S. sclerotiorum (MIC=32. 4 ug/ml after 288 hours) and B. cinerea (MIC=10. 8 ug/ml after 288 hours), and weak antifungal activity against F. solani, A. fumigatus and G. candidum.  Lacks antifungal activity against P. ultimum, T. viride and R. solani.  Inhibits the production of interleukin-2 by activated CD4+ T-cells with an IC(50) of 167. 3 nM.  Lacks cytotoxic activity against human peripheral blood mononuclear cells.
What are the official names of this protein?
Colutellin-A.
What are the subcellular locations of this protein?
Secreted.
Protein: O164A_CONVE
Sequence: MKLTCVLIVAVLFLTACQLTTAASYARSERQHPDLGSSDQNSKLTKRCLASGETCWRDTSCCSFSCTNNVCF
What are the official names of this protein?
Conotoxin VnMKLT2-021, Conotoxin VnMKLT2-0222.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RIMP_SALPB
Sequence: MGLSTLEQKLTEMITAPVEALGYELVGIEFIRGRTSTLRIYIDSEDGINVDDCADVSHQVSAVLDVEDPISVAYNLEVSSPGLDRPMFTADHYARFQGEEVALVLRMAVQNRRKWQGIIKAVDGEMITVTVEGKDEVFALSNIQKANLVPHF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y753_XYLFM
Sequence: MKPPEHSLIIISGLSGSGKSIALKTFEDLDYYCSDNLPVELLPHFLRRRLRVAELSDQRIAIGIDIRSGSNLSELDQWRHTAKHYNIKAHLLFFDASNETLLKRYADTRRRHPLSHLGLSLPEAIALERELTAPLREAAEAVIDTSTFNVHQLRRHVVTEFALTHSDKLSLLFESFAYKRGIPTEADFVFDARILPNPHWKPELRSLTGRDSNVRDYMEQQPDVILYLTQITEFLDTWLARLQADTRSYVTVAFGCTGGKHRSVYLAEQMARHAREKGWSEVATFHRELE
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Xfasm12_0753.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: RECF_THISH
Sequence: MILNRLEVRGLRILRHVRMDPVSGLNLVHGVNGAGKTSLLEAIHLLSTGHSFRTRQLSPLLAPDCDAVEVVARIQSTGGGEPWPVGIRKTRDSTTARIRGENVRSLADLARLLPLQVMHPESHLLVSGGPGYRRAFLDWGCFHTDPAYHDHWRRYRHLLCQRNAALRDRSPARLLSAWDTALGEAGSALDLARATHLQTLLPYLDSLKQELPETSGLALEYRRGWNPEESLSESLAHSVQRDRSAGFTQVGPHRAELLCRLDGRPVAQVASRGQQKSVVLMLKMAQSLWLMETLGFPPVVLVDDLPAELDARHRGWLMNCLQGLGSQVFVTAIESDQVPLSGWDSWQMFHVEHGTLRVGD
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE_ANADE
Sequence: MDKPRVRFAPSPTGYLHIGGARTALFNWLWARRNGGTFVLRIEDTDRERSTQLAVDAILDGLRWLGLDWDEGPGVGGPHPPYFQTERLDLYKAHAERLIREGKAYACYCTREELDAQRKQAEAEKRQFRYPGTCRDEPYDPSRPHVVRFRVPDAGATSWNDLVKGVISTPHDTLQDEVILRGDGVPLYNFGAVVDDITMEINLVGRGDDHVNNTARQILMYEALGYPVPTFAHFPMILGADKARLSKRHGATSVTAYRDLGFLPQAVVNYLVRLGWSHGDQELFTLDELVRYFDLKDVGATAGVFNLEKMAWVNHEWLKRLSPEELAKLALPHFRAAGLPAEDDEKLRHVCAVARERAKTLGEYVQQFRYFYAPIALDPKAKAKFLTADTRPVLQAVRDAIAALPALETQAVEQVFHGEAERRGVGLGKVAQPARVALTGGTASPGMYDVVQILGKDETLRRLDEAIRVAGQPG
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EXBB_PSEPU
Sequence: MTRTQPSASPTPSRAWRAIAALMFSLVLAPVAMADEPTANASTPAAAAAPATPAAAPAPAADGSAPVADAPAAAPVDAPVAVDPGVEALVEDTTLGMAHDLSPWGMYKNADIVVKIVMIGLAIASIITWTIWIAKGFELMGAKRRLRGEIAQLKKSASLKEASEVSNKEGTLAHTLVHDALEEMRLSANTREKEGIKERVAFRLERLVAASGRNMSSGTGVLATIGSTAPFVGLFGTVWGIMNSFIGIAKTQTTNLAVVAPGIAEALLATALGLVAAIPAVVIYNVFARSIAGYKAQVSDASAQVLLLVSRDLDHQGSERAAPHMVKVG
What is the function of this protein?
Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.  Protects ExbD from proteolytic degradation and functionally stabilizes TonB (By similarity).
What are the official names of this protein?
Biopolymer transport protein ExbB.
What is the protein family that this protein belongs to?
Belongs to the ExbB/TolQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYK_METBF
Sequence: MADTIHWADVIAEDVLKKSGKHLVATGITPSGNIHIGNMREVVTADAVYRALSNKGANADFIYIADNYDPLRKVYPFLPESYVEHVGKPISEIPCPCGNCANYAEHFLKPFLEALRRLGINPQVYRADEMYKTGKYTEAIKTALVKRDAIAKILEEVSGKTVAADWSPFNPRCNQCGKITTTKVTGFDLEAETVDYVCACGHSGIVPMAGGGKLTWRVDWPARWSVLGVTVEPFGKDHASKGGSYDTGKRIVREIFGHEPPYPIVYEWIMLGKQGAMSSSTGVVISISDMLEIIPPEVLRYLIIRTKPEKHIQFDPGQPLLTLVDEYERLRTQFRENDPSLGTFQKRVYELSRATGICQSEIPFKQMVTIYQVARGDFAQILKIVKRSGFSTEDKKCIKELADNVSKWLKLYAPPFAKFKVKEKVPVQAATLSELQRAFLSAFAALIESRGEISGEEYHMLVYSAKDEGSELNRKIAEKLNTHAPQVDPRELFKAIYFSLLGQKSGPKAGWFLSSFDKEFLVERFEEASNYSPEKQA
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BC7BA_DANRE
Sequence: MSGRSVRAETRSRAKDDIKKVMAAIERVRRWEKKWVTVGDTSLRIFKWVPVVDTKEKEKSKVSVGGEMQRKNFPSEESSDNACSVLLDFQDENSNQSSLSDSYQHKAAADSSNNSSPPASEPVSPAPQSLDYRTDDPQPPTLGQEIMEEPLLQSSEIADEPPTLIKEDLLPLTAQEDEDSCGAPPLKRICTEQVSVIQMVPLS
What are the official names of this protein?
B-cell CLL/lymphoma 7 protein family member B-A.
What is the protein family that this protein belongs to?
Belongs to the BCL7 family.
Protein: HUNKB_XENLA
Sequence: KVREGLHVGTGEKVAVKVIDKKKAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEEHEARKYIRQLILAVEHLHRAGVVHRDLKIENLLLDENNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLARKKYGPKVDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKDMNPLPTHISPAAISCLRSLLEPDPLKRPNIQQALANRWLNDNYHGKGHHTFPNRIHLEDLSQSVVLHMSEKLGYKHSDVINVILSNRACHTLAVYFLLNWKLEHYLVNMRKPDINDNVCHKNQFHQSEKYKMNKNSYEERRSKDLEKRGEQQQQRAIPRKLEKCSPSHRQSTCLTPQGHSSSKGPIKERRSSKSERESFGGLSPFHEVRITKTGCMNSCSLEYLEIQSPDPRTPKIMRRQDSHSQETVNVNMGSRIRETHLNVVRSFESVNREDQIESLSPNHQYRVLGSPMSFSPRHSSERTLSPIFHFDNTSPLKGHSNQASFTYDDKSSPSSPESMSPTSPHSPSCNNNISGNLGSPNCVRSRGRFPMMGIGQMLRKRNQVVSPKGEKPLETRMPPLHQMSPGYASFNSSDMNGFC
What are the official names of this protein?
Hormonally up-regulated neu tumor-associated kinase homolog B, Serine/threonine-protein kinase MAK-V B, xMAK-V B.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
Protein: BPI_HUMAN
Sequence: MRENMARGPCNAPRWASLMVLVAIGTAVTAAVNPGVVVRISQKGLDYASQQGTAALQKELKRIKIPDYSDSFKIKHLGKGHYSFYSMDIREFQLPSSQISMVPNVGLKFSISNANIKISGKWKAQKRFLKMSGNFDLSIEGMSISADLKLGSNPTSGKPTITCSSCSSHINSVHVHISKSKVGWLIQLFHKKIESALRNKMNSQVCEKVTNSVSSELQPYFQTLPVMTKIDSVAGINYGLVAPPATTAETLDVQMKGEFYSENHHNPPPFAPPVMEFPAAHDRMVYLGLSDYFFNTAGLVYQEAGVLKMTLRDDMIPKESKFRLTTKFFGTFLPEVAKKFPNMKIQIHVSASTPPHLSVQPTGLTFYPAVDVQAFAVLPNSSLASLFLIGMHTTGSMEVSAESNRLVGELKLDRLLLELKHSNIGPFPVELLQDIMNYIVPILVLPRVNEKLQKGFPLPTPARVQLYNVVLQPHQNFLLFGADVVYK
What is the function of this protein?
The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.  Has antibacterial activity against the Gram-negative bacterium P. aeruginosa, this activity is inhibited by LPS from P. aeruginosa.
What are the official names of this protein?
Bactericidal permeability-increasing protein, BPI, CAP 57.
What is the protein family that this protein belongs to?
Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic granule membrane. Note=Membrane-associated in polymorphonuclear Leukocytes (PMN) granules.
Protein: COAX_BURP6
Sequence: MCLLIDAGNSRIKWALADTARHFVTSGAFEHASDAPDWSTLPAPRGAWISNVAGDAAAARIDALIEARWPALPRTVVRASAAQCGVTNGYAEPARLGSDRWAGLIGAHAAFADEHLLIATFGTATTLEALRADGHFAGGLIAPGWALMMRSLGMHTAQLPTVSIDAATNLLDELAENDAHAPFAIDTPHALSAGCLQAQAGLIERAWRDLEKAWQAPVRLVLSGGAADAIVRALTVPHTRHDTLVLTGLALIAHSA
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PK4_PLAFA
Sequence: MKKRIRSSYKVGSSNKYHKKNYTDNEKDKKKYRSYKEKHINEKMFDKKEFLNFLTNFNKKFMKKNSLVDHLMKMNDKAEDNYDGYNSSGSRYNNINDDGVELCGTKRYTNNKNNSDYDNYNNNNNMKNKRYSNKKHNNDNIIINNNNNKYTDERKYRNKSIKEDVDYTNDYYNIQLNNNKINNNQTKNKIDTIRNISHEKLGNNKSSSARNLSLIQTSHIPYDAPLADFLENGRFLRTFENISLIGQGGFGSVYKVSHRLEPGSPTYAVKFIYLKVSSLDNVSSRRYFREIAANRDIYSKHVVRYYTWWCEEPQFLPMHLMPKEIQNLVKKNKDTFKKRLTKNKKYSNNCISDSSNNNNSSCYSASSYNSSINSNYRNMKLWIKKKEQSPDMKRYKEVLRKNNAPNLVFYSDNDGLTSKNKENPEKNHNPFLSDKNFSDSIYKKKKSHDYNSSSHKLKKRKNKKKKSKKKRKSKSKIKTNAQGIYEESENDEGRDHFQYKKGKEQFSKFIGKLILWVLHKVSKNMILLIMVILSEEDRDLIVFADNEESNGNDQQMIRHDNMNNENVIIKHRNEDDKNGLDGDKNGLDGDKNGLDGDKNGLDGDKNELDDNKNELDDLLMKQKINSLTRNDIVNIENENPAPHATNNIKNKKVDLNGELTYYDYVGKNEVIPNSRTETNVESINTNGMFNNKFSVMKDEGGEYKKKENMTWGDTKRDGLYENGKHEKDGLGVNKCITNKYIENDDDDDDDDDDNNNNNNIDERKKDLKKKQKNAITKGNEDLLATNGTNNKEKRKKDDDINKNMEKIKSYKKKTPVPEFSIVLLLQMELCKGYTLRKWLDRSTRSDKPLHFTYSDKKMNHPLEFDLFKQLIKGLKDIHATCFIHRDLKPENIFVDNDTYTLKIGDLGLVRFIEEKKREKDFNNIDCYKDNIYTDINQNRITSQISIKGQIIGTPGYTAPEGGALCDEKADIYSAALILLELLCPRFTTIMERYKRLNDFRNYYTVPDYVKIHLNPWYILMLQMSKPNPADRPSAADVYSKIKVLLDPHLTDFAFSFNDIHNEHMNKPPQGTNNFERITDNKDKFVIQSVVDMKNKVENEEIPIEKGLNSNVENIKNENNGADK
What is the function of this protein?
During the asexual blood stage, phosphorylates translation factor eIF2alpha in late schizonts resulting in protein translation inhibition (PubMed:9371731).  Plays a role in trophozoite differentiation into schizonts (By similarity).
What are the official names of this protein?
Eukaryotic translation initiation factor 2-alpha kinase PK4, eIF2alpha kinase PK4, Protein kinase PK4, PfPK4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.
Protein: END4_MYCAP
Sequence: MIKLGSHISFKSPNYLLGAAAESVNNKANCMMIYLGAPQTTKRVSVEKYKYNEYLEKYSKLITPDDIIVHAPYIVNPSSVSKNKFAIDFLVQEIEKMNYIGAKYLVLHPGSYTTFSVQESLDTFIASVKQILSRTKDVVICVETMAGKGAEVGINFDQINYFIHKIRNDRFAVCLDTCHIFDAGYDIRKYEEFKAEINKYNLLPHIKVIHLNDSKNSLGSHKDRHANIDKGFIGLETLAKFVHDPDFDNIPIILETPWVDNKPIYDQEIKMLLEHKAK
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: RL23_LACPL
Sequence: MEARDVILRPVVTESSMADLDDKRYTFDVNVQATKTQVKKAIEEIFDVKVVKVNVMNVKGKLKRQGRYAGYTKKRRKAIVTLSSDSNEIKLFNDDQQ
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: PK3C3_XENLA
Sequence: MGESDRFCYVYSCDLDISVRLKIGSLEGKREQKSYKAVLEDPMLKFSGLYQETCSDLYVTCQVFAEGKPLALPVRTSYKAFSTRWNWNEWLKLPVKYADLPRSAQVALTIWDVYGPGKAIPVGGATVSLFGKYGMFRQGMHDLKVWPNIEADGSELTKTPGRTNSSASEDQMSRLAKLTKAHRQGHMVKVDWLDRLTFREIEMINESEKRSSNFMYLMVEFPCVKCDEKEYGIVYYEKDGDESTPISTSSEIVRVPDPQMSMENLVEIKHHKLARSLRSGPSDHDLKPNAATRDQLNIIVSYPPTKQLTSEEQDLVWKFRSYLTSQEKALTKFLKCVNWDLPQEAKQALELLGKWKPMDVEDSLELLSSHFTNPTVRRYAVARLQQADDEDLLMYLLQLVQALKYENFEDIKSGLEPTKKDSQGPMLESMTTSGINPETDSSQILSNPLPAVSSPAPPSKTKDGLDAETLEQDLCTFLISRACKNSTLANYLYWYVIVECEDQDTQLRDPKTHEMYLNVMRRFSQALLKGDKSVRVMRSLLATQQTFVDRLVHLMKAVQRESGNRKKKNERLQALLGDNEKMNLSEFEPIPLPLEPQVKIRGIIPEKATLFKSALMPAKLYFKTEDGGKYPVIFKNGDDLRQDQLILQIISLMDKLLRKENLDLKLTPYKVLATSTKHGFMQFIQSVPVAEVLATEGSIQNFFRKYSPSEKGPYGISAEVMDTYVKSCAGYCVITYILGVGDRHLDNLLLTKTGKLFHIDFGYILGRDPKPLPPPMKLNKEMVEGMGGTQSEQYQAFRKQCYTAFLHLRRYSNLILNLFSLMVDANIPDIALEPDKTVKKVQDKFRLDLSDEEAVHYMQTLIDDSVNALFAAVVEQIHKFAQYWRR
What is the function of this protein?
Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways.  Involved in the transport of lysosomal enzyme precursors to lysosomes.  Required for transport from early to late endosomes (By similarity).
What are the official names of this protein?
Phosphatidylinositol 3-kinase catalytic subunit type 3, PI3-kinase type 3, PI3K type 3, PtdIns-3-kinase type 3, Phosphoinositide-3-kinase class 3.
What is the protein family that this protein belongs to?
Belongs to the PI3/PI4-kinase family.
What are the subcellular locations of this protein?
Midbody.
Protein: G0S2_RAT
Sequence: MESVQELIPLAKEMMTQKSRGKLVKLYVLGSVLAFFGVVLGLVETVCSPFTAASRLRDQEAAVAELRDACEQQSLHKQALIAEGKTQEATLCSRALSLRQHAS
What is the function of this protein?
Promotes apoptosis by binding to BCL2, hence preventing the formation of protective BCL2-BAX heterodimers.
What are the official names of this protein?
G0/G1 switch protein 2, G0S2-like protein.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GAL1_BACSU
Sequence: MREELKGIFASVFGEKEGLRFFFAPGRVNLIGEHTDYNGGHVFPCALTMGTYAAVAERNDGLVRMYSDNFRNAGIKECSLDDIRYQKEDDWANYPKGVIYEFQQRGYAVPHGFDIVFSGNIPNGAGLSSSASIELLMGVVLQSYFHPEVDALELVKMAQHAENHFIGVNCGIMDQFAIGMGKKHHAMLLNCDTLDYEYSKLNVSGLALVIANTNKKRTLADSSYNTRRQECNDALLDLKKGLDIAALGDIKPSDFDAHSSLIQNETNRRRAKHAVYENHRAIKTAHMFKENNIDEIGQLMKESHLSLKDDYEVTCPELDELVFAAWDHEGVIGSRMTGAGFGGCTISIVKDEFVDDFIQKVGDRYQEKTGLRADFYVADIGEGARELKGE
What is the function of this protein?
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA_PSEPW
Sequence: MTEQQPVAVLGGGSFGTAVANLLAQNGVPVRQWMRDPEQAEAMRVNRENPRYLKGIRLHDGVEPVNDLLATLHYSDLIFVALPSSALRSVLAPHAGLLRGKCLVSLTKGIEAQSFKLMSQILEEIAPDARIGVLSGPNLAREIAEHALTATVVASEDEDLCQRVQAVLHGHTFRVYASSDRFGVELGGALKNVYAIIAGMAVALGMGENTKSMLITRALAEMTRFAVSQGANPMTFLGLAGVGDLIVTCSSPKSRNYQVGHALGQGLTLEQAVNRLGEVAEGVNTLKVLKAKAEEVQVYMPLVAGLHAILFEGRTLNQVIERLMRAEPKTDVDFISISGFN
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF6_PYRHO
Sequence: MHIERLDFENSPYLGVFGVATDRVVLIREGLQEKKLEVIRETLKVPVIEVSVMKSRIIGTLATGNSNAIILPWYVWDAEIERIKKALSEYGIDMEVVPFRSKYTALGNLILTNDKAALVSAKFSRKEAQEIGEILGVEVERGVIAGLHAVGSAGVVTNKGGLVHPETSDEELEWLSDLFKVDVYVGTANMGVPYVGTCMLANSNGVVVGHLTTGPEIVKIEEALGFV
What is the function of this protein?
Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.
What are the official names of this protein?
Translation initiation factor 6, aIF-6.
What is the protein family that this protein belongs to?
Belongs to the eIF-6 family.
Protein: LSPA_ALKCK
Sequence: MAYIVALIIIALDQLTKWLVVTSMELGERIPIIDQVLYLYSHRNTGAAFGILQGQMWFFYVVTTIIVGVIIYLIQTEAKGNRLLKIALGLVLGGAIGNFIDRLLRQEVVDFIDTFGDFPIFNIADSALTIGVGLFLLNILIQGRNEKRSTR
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: 5HT1A_RAT
Sequence: MDVFSFGQGNNTTASQEPFGTGGNVTSISDVTFSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVRKVEKKGAGTSLGTSSAPPPKKSLNGQPGSGDWRRCAENRAVGTPCTNGAVRQGDDEATLEVIEVHRVGNSKEHLPLPSESGSNSYAPACLERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPALLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRR
What is the function of this protein?
G-protein coupled receptor for 5-hydroxytryptamine (serotonin).  Also functions as a receptor for various drugs and psychoactive substances.  Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase.  Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways.  Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores.  Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism.  Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior.  Plays a role in the response to anxiogenic stimuli.
What are the official names of this protein?
5-hydroxytryptamine receptor 1A, 5-HT-1A, 5-HT1A, Serotonin receptor 1A.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. 5-hydroxytryptamine receptor subfamily. HTR1A sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell projection, dendrite.
Protein: RS10_DESHY
Sequence: MSSQKIRIRLKAFDHKTLDQSAEKIVETAKRTGARVSGPIPLPTEKSIYTILRSPHVNKDSREQFEMRTHKRLIDILEPTSKTVDALMRLDLPAGVDIEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: EFM1_YEAST
Sequence: MITQTELDNCLQWAQNNGAFIDPKISFRITEDAGVSAFVNEKFSPKPDQALIRVPETLLITSQQALSEFSQAANERSLLNSVTQLYLSKLKFGTDAVHLKSFYKPYLDVLPLHLPQPYFWSTDEVMNLHGTDVYLTMRDTLNKLVKEWRMLFQALSIEHSSQDKQFLSLFQENKDSAVVPLEQFCAHINGCKLEDSEWNSFVAYLWSYCIFNSRAFPRVILGRAGTDRTNLNEGFLYPIVDLLNHKNDVPVRWEMNEQNELCFMSQTTTFSAQDELFNNYGNISNEKCLLNYGFWDSSNKFDFSRLTLKLPSTLVSGLPVDFNKSGNFVTDDGETTILQFSLKISEPLPPVLLALFAYLSKLKSEETPTVRSVLEGIDQLTSVVSQRLLFYKNFKIKTSSTQKLRPHVIKLIKLYYQDNKKILNATTEKLSVLQKKIYSNNKEFSLSFKTIFKNDKIFANSLLLVFGAINYEDLITKDCLNDALLLWIVKLINDKSNNQGGFIKQTFKEVSDSIVIEKEDVMEFLPFYKKYFPNLSERIPEIYSVGDWGIRQFIVADTAIDRLVWIRKSNKEPIFLMKKAYDLQI
What is the function of this protein?
S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that monomethylates elongation factor 1-alpha (TEF1/TEF2) at 'Lys-30'.
What are the official names of this protein?
Protein-lysine N-methyltransferase EFM1, Elongation factor methyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. RKM1 family.
Protein: DHX15_CAEEL
Sequence: MSSRHRLDLDGSGRGDRRRSPNRRSRSRSRSPHRRSSPDRKRQIGAVGNMKIQINPYNNQPFSNRYWAIWEKRSQLPVWEYKEKFMELLRNNQCITLVGETGSGKTTQIPQWAVEFMKQQQQGQPPGQARLVACTQPRRVAAMSVATRVAEEMDVVLGQEVGYSIRFEDCISERTVLKYCTDGMLLREAMNSPLLDKYKVLILDEAHERTLATDILMGLIKEIVRNRADIKVVIMSATLDAGKFQRYFEDCPLLSVPGRTFPVEIFFTPNAEKDYLEAAIRTVIQIHMVEEVEGDILLFLTGQEEIEEACKRIDREIQALGADAGALSCIPLYSTLPPAAQQRIFEPAPPNRPNGAISRKCVISTNIAETSLTIDGVVFVIDPGFSKQKVYNPRIRVESLLVCPISKASAMQRAGRAGRTKPGKCFRLYTETAYGSEMQDQTYPEILRSNLGSVVLQLKKLGTEDLVHFDFMDPPAPETLMRALELLNYLQAINDDGELTELGSLMAEFPLDPQLAKMLITSTELNCSNEILSITAMLSVPQCWVRPNEMRTEADEAKARFAHIDGDHLTLLNVYHSFKQNQEDPQWCYDNFINYRTMKTADTVRTQLSRVMDKYNLRRVSTDFKSRDYYLNIRKALVAGFFMQVAHLERSGHYVTVKDNQLVNLHPSTVLDHKPEWALYNEFVLTTKNFIRTVTDVRPEWLLQIAPQYYDLDNFPDGDTKRKLTTVMQTLQRNAGRGY
What is the function of this protein?
Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA.
What are the official names of this protein?
Pre-mRNA-splicing factor ATP-dependent RNA helicase ddx-15, DEAH box protein 15.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: MENE_BACCQ
Sequence: METMPNWLMQRAFLTPDRTAIEIEEEKVTFMQLHEKVVSVCGNLTHVGVKRGQKVAVLMKNGMEMITVIHALSYVGAVAVLLNTRLSREELLWQMDDAEVICLVTDQDFEAKDIPVYSFAEVMNGPKEEAFIQEEFSLEEAMTIIYTSGTTGKPKGVILTYGNHWASAVGSSLNLGLRDDDCWLACMPMFHVGGLSLLMKNIMYGMRILLVPKYDADFIHKALQTRGVTIISVVSKMLTDLLERLGAETYPSSLRCMLLGGGPAPKPLLETCVEKGIPVYQTYGMTETSSQICTLSADYMLTKVGSAGKPLFQCQLRIEKDGVVVPAFTEGEIVVKGPNVTGGYFNREDATRETIQNGWLHTGDLGYLDEEGFLYVLDRRSDLIISGGENIYPAQIEEVLLSHPAVAEAGVVGMTDDKWGQVPAAFVVKSGEVTEEEILHFCEEKLAKYKVPKKACFLEELPRNASKKLLRRELRQLVEEM
What is the function of this protein?
Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).
What are the official names of this protein?
2-succinylbenzoate--CoA ligase, o-succinylbenzoyl-CoA synthetase, OSB-CoA synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.