PharMolix/UniProtQA huggingface dataset:
Protein: SYM1_BACCR
Sequence: MTEENKSFYITTPIYYPSGKLHIGHAYTTVAGDAMARYKRMQGYNVHYLTGTDEHGQKIQKKAEELNITPQAYVDNIVAGIKELWEKMNISYDDFIRTTEDRHKDVVEKIFKQLVDQGDIYLDEYEGWYSVQDETFYTEHQLVDPIMEGDKVVGGKSPDSGHDVELVREESYFFRMGKYVDRLLKFYEDNPHFIQPESRKNEMINNFIKPGLEDLAVSRTSFDWGVRVPGNPKHVIYVWVDALSNYITALGYGTANEEKYKKFWPADVHLVGKEIVRFHTIYWPIILMALDLPLPKKVFAHGWILMKDGKMSKSKGNVVDPVTLIDRYGLDALRYYLLREVPFGSDGVFTPEGFVERINFDLANDLGNLLNRTVAMIDKYFSGEIPAFKANVTEFDETLVAFAQDTLKKVEEAMENMEFSVALGSIWQLVSRTNKYIDETQPWVLAKDENDREKLASVMAHLAEVLRQTGIMLMPFLTVAPSKMFAQLGLTDEAHKSWESLSTIGCIPAGTKVEKGNPIFPRLEMEVEVEYIKEQMKSSAPKVEEKKEEEPKAEEITIDDFFKVELRVAEVLSAEPVKKADKLLKIQLDLGTEKRQVVSGIAKFYSPEDLKGKKVICVTNLKPVKLRGELSQGMILAGEENGVLSLASIDQNLPNGTKIK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase 1, Methionyl-tRNA synthetase 1, MetRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14Z_BACC1
Sequence: MAKKSMIAKQKRTPKFKVQEYTRCERCGRPHSVYRKFKLCRICFRELAYKGQIPGVKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: DID1A_MACLB
Sequence: MIQVLLVTICLAVFPYQGSSIILESGNVNDYEIVYPKKVTVLPTGAMNSGNPCCDPVTCKPRRGEHCVSGPCCRNCKFLNAGTICNRARGDDMNDYCTGISSDCPRNPYKD
What is the function of this protein?
Strongly inhibits ADP-induced platelet aggregation on human platelet-rich plasma.  Also avidly binds to the laminin-binding beta-1 integrins (alpha-3/beta-1, alpha-6/beta-1, and alpha-7/beta-1) in an RGD-independent manner.
What are the official names of this protein?
Disintegrin lebein-1-alpha, ML-3, MS-II, Platelet aggregation activation inhibitor.
What is the protein family that this protein belongs to?
Belongs to the disintegrin family. Dimeric disintegrin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ERO1_KLULA
Sequence: MVKVLQLCFLSAISLVQALNSTVDQKDEAKVDINTVFDNDSTNFCRMDKTEAIGATCDVTFHEINEVNNNIRPQLLSLVQSDFFKYFKLDLYKECPFWSDNNGYCVNRACAVDVVEDWDSLPEYWQPEILGNIENATTDITDDECSFLDELCDKPRFEAEKDIEYCDTNDFNSQHSVLVDLTANPERFTGYGGEQSSQIWSSIYKENCFSLGDENQCLAKDAFYRLISGLHASIGTHLSNEHLNTETGKWEPNLELFMTRVGNFPDRVSNIYFNFAVVAKALWKIRPYMNELGFCNAYNEDVKGMIDGVVSQLNSKVFNEDLLFHDEVSGQLKDDFRIRFKNVTKIMDCVQCDRCRLWGKVQTTGYATSLKILFEMDNDDDVARQHVVDKLTKYELIALFNTFDRLSKSVEAVNRFEEMYNYQLKSPGEKLASFFQLDNFFKVLNDKFNSANHSSQEKESVSNVEKKVNEFNDLKMPEKKKETHTEVREQASGVFKEAWDVEWKNFKQALRFIVTSYTDLPSTVSKYTVLKLNKLWNKFIGVPNYLEEGEELEYPSYNYEE
What is the function of this protein?
Essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds.  Acts by oxidizing directly PDI1 isomerase through a direct disulfide exchange.  Does not act as a direct oxidant of folding substrate, but relies on PDI1 to transfer oxidizing equivalent.  Does not oxidize all pdi related proteins, suggesting that it can discriminate between PDI1 and related proteins.  Its reoxidation probably involves electron transfer to molecular oxygen via FAD.  Acts independently of glutathione.  May be responsible for a significant proportion of reactive oxygen species (ROS) in the cell, thereby being a source of oxidative stress (By similarity).
What are the official names of this protein?
Endoplasmic reticulum oxidoreductin-1.
What is the protein family that this protein belongs to?
Belongs to the EROs family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side.
Protein: TM138_XENTR
Sequence: MLQPGNYSLVLSLQFLLLLFDLFVNSFSELLRDPPVNQLVLFILQDVGILFAAIVLFLMLFNTFVFQAGLVSLLCQRFQVTVILCAVYIALSISLHVWLMNLRWTGANRFVWSDGLLALFVLQRFVAVLYFYYYKRTALSMGDSRFYHDSLWLRKEFARVRG
What is the function of this protein?
Required for ciliogenesis.
What are the official names of this protein?
Transmembrane protein 138.
What is the protein family that this protein belongs to?
Belongs to the TMEM138 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Cell projection, cilium. Note=Localizes to vesicles en route to the base of cilium.
Protein: AROE_SHESA
Sequence: MTDMPSVTTPALDRYAVFGNPIGHSKSPFIHGQFASLTQQTLSYEAILAPIDGFEASLRAFFQAGGKGANVTVPFKEQAFALCDSLSAEATLAGAVNTLSLLADGTIYGDNTDGLGLVADLVRHLGSLQHKRVLLVGAGGAARGCILPLLKAEVGQLVITNRTQSKAQALVDIFSQVQEGRYSDKLQAVSMSELSGVFDLVINSTSASLAGELPPLSQSIIGNKTACYDMMYGAKPTAFNQWALQQGAAQVIDGLGMLVGQAAKSFALWRGVEPDTSGVLKLLRDKLQVDAQ
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: RNP1_METMP
Sequence: MSQNILRHELIGLNLEVVKSTDSGLISTKGRVINETRNTLVLEKENGKEITLVKEISTFRIQFESENVVKIDIDGRLLVGRPEDRLKRKIKQLYSY
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 1, RNase P component 1, Rpp29.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPF_PSEA6
Sequence: MQVQFSKMHGLGNDFVVIDNVTQNVFFSKEKISQLADRNFGIGFDQLLVVEPPYDPEQDFHYRIFNSDGSEVSQCGNGARCFARFVKMKGLTNRNKIVVSTKAGRIVLYHERDGQITVNMGEPIFEPAKIPLKANKQENIYIIRENDHTFFCGAVSMGNPHCVLLVDDVETADVEGIGKTLVAHERFPEGANIGFMQILNSGHIKLRVYERGVGETLACGSGACAAVAVGQMQKKLNKEVTVDLPGGTLKIRWQGPGSILKMTGTAEHVFDGNITL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPG_ALIFS
Sequence: MSEQTANKETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDASDKLRFKALSNGDLYEGNADLGVKLSFNEAANTLTISDNGIGMSREDVIEHLGTIAKSGTADFFSKLSEDQSKDSQLIGQFGVGFYSAFIVADAVTVRTRAAGSEKDQGVQWHSEGEGDYTIEDITKESRGTDIILHMREEGKEFLNEWRLKEVIGKYSDHIGIPVSIWAVEKDEEGKDKEGKWEQVNKAQALWTRSKSDIEDAEYQEFYKHVSHDFADPLTWSHNKVEGKNDYTSLLYIPAKAPFDMMNRDHKSGLKLYVQRVFIMDDAEQFMPTYLRFVKGLIDSNDLPLNVSREILQDNKVTQSLRSACTKRVLGMLEKMAKKDDEKYLTFWKQFGQVLKEG
What is the function of this protein?
Molecular chaperone.  Has ATPase activity (By similarity).
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CF298_MOUSE
Sequence: MVVLHVKRGDESQFLLQAPGSTELEELTAQVARVYNGRLKVHRLCSEMEELAEHGVFLPPNMQGLTDEQIEELKLKDEWGEKCVPSGGSVFTKDEIGRRNGQAPNEKMKQVLKKTVEEAKAIVSKKQVEAGVFVTMEMVKDALDQLRGAVMIVYPMGLPPYDPIRMEFENKEDLSGTQAALEVIQESEAQLWWAAKELRRTKKLSDYVGKNEKTKIIVKIQQRGQGAPAREPVISSEEHKQLMLFYHRRQEELKKLEENDDDSCLNSPWADNTALKRHFHGVKDIKWRPR
What is the function of this protein?
Plays a role in motile cilium function, possibly by acting on outer dynein arm assembly.  Seems to be important for initiation rather than maintenance of cilium motility.  Required for correct positioning of cilia at the apical cell surface, suggesting an additional role in the planar cell polarity (PCP) pathway.  May suppress canonical Wnt signaling activity.
What are the official names of this protein?
Cilia- and flagella-associated protein 298, Protein kurly homolog.
What is the protein family that this protein belongs to?
Belongs to the CFAP298 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, cilium basal body. Note=Partially colocalized with SASS6 in cytoplasmic puncta, suggesting a centrosomal localization.
Protein: RL27_BORBR
Sequence: MAQKKGGGSTRNGRDSESKRLGVKVYGGQSILAGSIIVRQRGTRFHPGVNVGVGKDHTLFALANGKVHFSVKGALNKPTVSVVAAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: RLMM_METCA
Sequence: MTSPSSILLYCRRGFEKECAAEILVQTQAAGISGHVRAKENSAYVVFVAHEPEILANRAARLRFDALIFARQRIFASGPLADLPVDDRITPLLDTAAGLQRRYSTLWLETADTNEAKELAAFTRKFERPFAAAAAGLLGGGPQAPRLHVFFLTSTAAYLGYTLPDDSAPWPCGIPRLKLPRSAPSRSTLKLEEAFLVFVDRPETMLRPGMSAVDLGAAPGGWTWQLVRRHIRTTAVDNGNLDPALLDSGLVTHLRTDGFRFRPSRPVDWLVCDMVEQPSRIARLVADWAADGAFRYAVFNLKLPMNRRYEEVERCRGLIEERLAAQGVSHRLRFRQLYHDREEVTGFLELVS
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHYS_SOLLC
Sequence: MGEALKYSIMDSVRSVVFKESENLEGSCTKIEGYDFNKGVNYAELIKSMVSTGFQASNLGDAIAIVNQMLDWRLSHELPTEDCSEEERDVAYRESVTCKIFLGFTSNLVSSGVRDTVRYLVQHRMVDVVVTTAGGIEEDLIKCLAPTYKGDFSLPGASLRSKGLNRIGNLLVPNDNYCKFENWIIPVFDQMYEEQINEKVLWTPSKVIARLGKEINDETSYLYWAYKNRIPVFCPGLTDGSLGDMLYFHSFKKGDPDNPDLNPGLVIDIVGDIRAMNGEAVHAGLRKTGMIILGGGLPKHHVCNANMMRNGADFAVFINTAQEFDGSDSGARPDEAVSWGKIRGGAKTVKVHCDATIAFPILVAETFAAKSKEFSQIRCQV
What is the function of this protein?
Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.  Also able to produce homospermidine from putrescine (By similarity).
What are the official names of this protein?
Deoxyhypusine synthase.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine synthase family.
Protein: RSME1_BORBU
Sequence: MNLMLITFNEFKTGISLNDTRAEHLVKILKLKDNDKFKFGILGEKNIYHCIYKKDKKLFFKKIFKVGESNKLKKLYVLIGMIRPIVAKRIIKELASIGTYKIIFFNTELTEKSYLNSKIFKNNDCEKHLIAGAMQGKITYLPKIKIIKNLKESLKYIQQENFEIKILLEKNSEKNLIDIEQINNAVIIVGPERGFTEKEKQLIAQYNFSPYSISTNTLRTETATIAASIITASKLINM
What is the function of this protein?
Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA.  Acts on the fully assembled 30S ribosomal subunit (By similarity).
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase E 1, 16S rRNA m3U1498 methyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RsmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATZ_SALSV
Sequence: MKEIISRHKAGEQIGICSVCSAHPLVIESALRFDLNSGNKVLIEATSNQVNQFGGYTGMKPADFRDFVYGIAQEVGFPRERLILGGDHLGPNCWQNEPADTAMEKSVELIKAYVAAGFSKIHLDASMSCADDPTPLDPMVVAKRAALLCQAAETTATDEQKRHLTYVIGTEVPVPGGEASAINAVHVTREQDAARTLQTHQAAFRALGLDEALNRVIAIVVQPGVEFDHTQIIHYQPQAAQALSAWIKETPMVYEAHSTDYQTRQAYRALVRDHYAILKVGPALTFALREAIFALAQMENELVSPEQRSRVMEVIDEVMLNEPGYWKKYYRPTWSQAMIDIHFSLSDRIRYYWPHPRIRQSVEKLIANLNNVTLPLGLISQFMPVQFERLSEGVLTPTPHNLIIDKIQDVLRAYRFGCTPDVA
What is the function of this protein?
Component of the tagatose-1,6-bisphosphate aldolase GatYZ that is required for full activity and stability of the Y subunit.  Could have a chaperone-like function for the proper and stable folding of GatY.  When expressed alone, GatZ does not show any aldolase activity.  Is involved in the catabolism of galactitol.
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit GatZ.
What is the protein family that this protein belongs to?
Belongs to the GatZ/KbaZ family. GatZ subfamily.
Protein: AIM3A_CANGA
Sequence: MDSLKSGLATAGKFTYKGTKTVAKAGYNTSKKHMHKKDKDTHHTDHHEEDEYSEDYHTPRSVNTLRDPSSFPPPPTRSGQAGHVAGNTAGSIAGNYSGYSQPTAAANNTISYNAQAQNTPYSSPAQQQPVSPQPPVQNSQYNPTQNYAIQQPQQPAGTNANYSYGNQQHPAGQAPIVNSITPNHQYNANNTFQSNLPNQQLNVAAPTQSTNNNFNQMAANNTYTNSAQVAYNSQQQQLQQNSQQNTYSNAPYQVQAQAAYNPLPQQQQQQQQQPEYNTQLQQNQQLHNQQAYGQQQQIYSNNTQPQYVSQTQQTSYTQNAPPQQTRSPEQPVYGQGITPPVQANAYRPMPSIPPDVNQTAITSTNSANEALQNRIPMNNVDLSSLPPPPTHRDRGRASVENETIDENMQTNNSTIDSSSVASADINNNSIRNIPAPAVGPPGAATRAVPPPPPRRTTSQSMSTNSVVETSPGINSIEQINNYYDGTYAGHSANERPPITNTLKRGTPPLPRRSTSTKMNTQPNPQTPISPSRDTNMDLQRRSTVSSIQSSNRPMPDPPIRKDNIQENNIESKQVNQEVNSQMSVSNIGIGDITSELQHIKLKSVGNSYEREIHGEAATEVVHNKPLKKKPPTVPKKKDSLKGKAPPPVPKKKPTLTSFVHS
What are the official names of this protein?
Altered inheritance of mitochondria protein 3-1.
What is the protein family that this protein belongs to?
Belongs to the AIM3 family.
What are the subcellular locations of this protein?
Membrane raft; Peripheral membrane protein. Note=Localizes within detergent-insoluble glycolipid-enriched membranes.
Protein: SYFA_SALTY
Sequence: MSHLAELVANAAAAINQASDVAALDNVRVEYLGKKGHLTLQMTTLRDLPPEERPAAGAVINAAKEQVQQALNARKAELESAALNARLAAETIDISLPGRRIENGGLHPVTRTIDRIESFFGELGFTVATGPEIEDDYHNFDALNIPGHHPARADHDTFWFDATRLLRTQTSGVQIRTMKAQQPPIRIIAPGRVYRNDYDQTHTPMFHQMEGLIVDTNISFTNLKGTLHDFLRNFFEEDLQIRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRNVGIDPEIYSGFAFGMGMERLTMLRYGVTDLRSFFENDLRFLKQFK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDRP_ACLSP
Sequence: MAFSYRTPQEELLSRLPQSQQEVISGFQYERIQKEEEKKVENFSFYLPEKTREWFTKSGVYLSPFAYVNHSHPGCKTLENHLLFNVVASYISKYSYVACLSIKSNKMSKMERLGPNSVKTYDILNRLVTAKDKARYGPLAKPERSPCPKKTNIFIHDEIHYWSRDQLETFLQVHRPKNLWATLVFPPEILAGYKSSVLPFLYQFEIHGKDLVYMPDGVRSESYTQPLENGFLLSSSSIIIKNRVTGVEIRYQVSLVYSLGSHHLFHIYPAEDLMKEEVRRFGPYDLFDVGSLFVKPVRVPIQDFPLSVFKKIFIYMSSLKKPDVQSAVAKLRQLSDADISIESVFMIQEFASRIEKNGVESWSCSFWGCMKDWFFDKLPYREVLEKIGLADDFTRRLMKIKPLAFDIHTTDRPLTVRMIIDQIWEERLSSFDNISNIVFYGRREWLNNGVLPKVKKKGLAKLIPGREVDSHNYPREIYSDLLSSTSIWRSYDDDFRHRSASPLVILRSNRAYSEAAKFSSNCLSLCAAPCDEVIARTPFELNHRREKKELSLKCLDFHIKKMKVKNVLELEVKLRERNTRISLSKKGVKKAGRSRMIPVHLLKPTCGEGNGKPEERNKEEAKIPMNEGTSKEEKGSEPPHSEVKREGVRLDEQHISEPLLSFKLDDFVGREKLCSAGLIKTVGNDYLLLARQIECMPLSQLRGKKAAYFCLDFPMVYFHDKVSYPTFEATGEIRHVMMKARSKWGIDFNSALIQVYNDGCRLPLHSDNEECYDDDGILTINVVGDAKFHTTCHDEVIDLKQGNEILMPAGYQKKNRHAVEVASEGRTSVTLRVHKRDFSFESKLRFIKGKFDCLFVSVAEIIHKKPEEIMMFIPHIMDRCVSNRGCSLDDAKAICEKYEIKIECEGDCGLVECGTSGLSIGRMLLRGNHFSVASVRRSSMDSLANSSKEIKSDGVLDHVTFNFHKRLKLVEPDLTNADIKVDSSRAGKLLKSLMDGMTGIVSHNSTHEGWRMIKGINSTSEMRSFMNMVRGQIEEPKSDLFDKVQELNFMKVKIYGIFGFAGSGKSHAIQNLIQTEFKGSQGIMVICPRRFLAKDWSEKGVDEKDIKTFESALKSDVKGKRLFILDEISLLPKGFTDLLMLKMHMEGILKKSTIVCIGDPLQAGYFCPKDDNYLSREGEIKRLFKGGVNYKWYSYRINKFIAKKLAIETMNDFIGIDEQSSIYKDMPSAHHFMEKKGNHIEVILVASMVEKELYSNYGNVMTFGESQGLTFNCGVIVLSEEAKLCSDAHIMVAITRFRRGFCFALGSKGSKEDYMRSMKSGLLQRICSGVGASKEFILGSSSVNLILSEKDIAKGAGIDEMDREARLEGDVWLKSMIYLGKRYHMVEPLGQVIKLTDDAIKCHIPVCSSQTLGPELDNIQAREYREFKGKNGWSNQFREEAGPNWKFPYKVNQAMSYEAVYPRHKMDDDLTFLAAIKKRLRFDNVANNYAKFKAAESRGKYLTKIFLKHVPIKCGRDQRLLDQCRQEFEETKLSKSAATIGAHSQRSDSDWPLDKIFLFMKSQLCTKFEKRFTEAKAGQTLACFPHKILVEFSPWCRYTEKVLTANLPDNYYIHQRKNFSELEDFARRFSNGSICVESDYTAFDVSQDHTILAFEVELLRHFGWDDRVLQSYIKMKCTLGCRLGGFAIMRFTGEFSTFLFNTLANMVFTFCRYEVPDGTPICFAGDDMCALRNLREIDTHEFILSKLSLKAKVNRTKVPMFCGWRLCCDGLIKEPCLIYERLQVAIENGRLMDVIDSYFLEFSFAYKLGERLYSHLEIEQLNYHQVLTRFFIRNKHLLRGDSRHNISELEWLSDEDGDNDKGSQIEDRRRGYSNCWGEKLQNLF
What is the function of this protein?
Involved in viral RNA replication.
What are the official names of this protein?
RNA-directed RNA polymerase, 216.5 kDa protein, ORF1 protein, RNA replicase.
Protein: PVR_CHLAE
Sequence: MARTMAAAWPPLLLTLLELSWPPPGTGDIIVQAPTQVPGFLGDSVTLPCYLQVPGMEETHVSQLTWSRHGESGSMAVFHQTQGPNYSEPKRLEFVAARLGTELRDASLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGKPVPVARCVSTGGRPPAHITWHSDLGGMPNTSQAPGFLSGTVTVTSLWILVPSSQVDGKSVTCKVEHESFEKPQLLTVNLTVYYPPEVSISGYDNNWYLSQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIRPVDKPINTTFICNVTNALGARQAELTVQVKEGPPSEPSGMSSNIIIFLILGIVILLTLLGIGVYFYRSRCSREFLWCHHLSPSSEEHASASANGYISYSDVSREASSSQDPQTEGTR
What is the function of this protein?
Mediates NK cell adhesion and triggers NK cell effector functions.  Binds two different NK cell receptors: CD96 and CD226.  These interactions accumulates at the cell-cell contact site, leading to the formation of a mature immunological synapse between NK cell and target cell.  This may trigger adhesion and secretion of lytic granules and IFN-gamma and activate cytotoxicity of activated NK cells.  May also promote NK cell-target cell modular exchange, and PVR transfer to the NK cell (By similarity).
What are the official names of this protein?
Poliovirus receptor homolog.
What is the protein family that this protein belongs to?
Belongs to the nectin family.
What are the subcellular locations of this protein?
[Isoform Alpha]: Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform Beta]: Secreted. SUBCELLULAR LOCATION: [Isoform Gamma]: Secreted.
Protein: Y132_CHLPN
Sequence: MIEFAFVPHTSVTADRIEDRMACRMNKLSTLAITSLCVLISSVCIMIGILCISGTVGTYAFVVGIIFSVLALVACVFFLYFFYFSSEEFKCASSQEFRFLPIPAVVSALRSYEYISQDAINDVIKDTMQLSTLSSLLDPEAFFLEFPYFNSLIVNHSMKEADRLSREAFLILLGEITWKDCETKILPWLKDPNITPDDFWKLLKDHFDLKDFKKRIATWIRKAYPEIRLPKKHCLDKSIYKGCCKFLLLAENDVQYQRLLHKVCYFSGEFPAMVLGLGSEVPMVLGLPKVPKDLTWEMFMENMPVLLQSKREGHWKISLEDVASL
What are the official names of this protein?
Uncharacterized protein CPn_0132/CP_0640/CPj0132/CpB0133.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: URK_BACHK
Sequence: MGTNKPVVIGIAGGSGSGKTSVTKAIFDHFKGHSILILEQDYYYKDQSHLPMEERLKTNYDHPLAFDNDLLIEHLQQLLAYKQVDKPVYDYTLHTRSEEIIPVEPKDVIILEGILILEDPRLCELMDIKLFVDTDADLRILRRMQRDIKERGRTMDSVIDQYVNVVRPMHNQFIEPSKKFADIIIPEGGQNHVAIDIMVTKIATILEQKVNL
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y100_SYNY3
Sequence: MELKNLAQTLLPRLVEIRRHLHAHPELSGQEYQTAAYVAGVLSSCGLHVEEAIGKTGVVGQLSGKGDDPRLLAIRTDMDALPIEEMVSLPFASRHPGVMHACGHDIHTTLGLGTAMVLSQMGHRLPGDVRFLFQPAEEIAQGASWMIQDGAMKGVSHILGVHVFPSIPAQQVGIRYGALTAAADDLEIFIQGESGHGARPHEAIDAIWIAAQVITALQQAISRTQNPLRPMVLSLGQISGGRAPNVIADQVRMAGTVRSLHPETHAQLPQWIEGIVANVCQTYGAKYEVNYRRGVPSVQNDAQLNKLLENAVREAWGESALQIIPEPSLGAEDFALYLEHAPGAMFRLGTGFGDRQMNHPLHHPRFEADEAAILTGVVTLSYAAWQYWQNIAI
What are the official names of this protein?
Probable hydrolase sll0100.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20 family.
Protein: GPMI_VIBC3
Sequence: MSAKKPMALVILDGWGYREDNANNAINNARTPVMDSLMANNPHTLISASGMDVGLPDGQMGNSEVGHTNIGAGRIVYQDLTRITKAIMDGEFQHNKVLVAAIDKAVAAGKAVHLMGLMSPGGVHSHEDHIYAAVEMAAARGAEKIYLHCFLDGRDTPPRSAEASLKRFQDLFAKLGKGRIASIVGRYYAMDRDNNWDRVEKAYDLLTLAQGEFTYDSAVEALQAAYAREENDEFVKATEIRAAGQESAAMQDGDALLFMNYRADRARQITRTFVPDFAGFSRKAFPALDFVMLTQYAADIPLQCAFGPASLENTYGEWLSKAGKTQLRISETEKYAHVTFFFNGGVENEFPGEERQLVASPKVATYDLQPEMSSKELTDKLVAAIKSGKYDAIICNYPNGDMVGHTGVYEAAVKACEAVDECIGRVVEAIKEVDGQLLITADHGNAEMMIDPETGGVHTAHTSLPVPLIYVGNKAISLKEGGKLSDLAPTMLALSDLDIPADMSGQVLYS
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: SCARF_DROME
Sequence: MSASHFREQLALCITLAVLAAASGDYRANMFLNGQYQNGIKDQKENNLLVNPSTNVFLNHAIISRQASPFQGPTYLPPKEFLKCAPGQQCVRSGQCLNGYFAQQLPKIQNCDPETTVCCTYRPPPTTTTTTTTSVPVANCAYDSDCVTPDNCRNGEISAINYVKKQGPNRCPAPNICCRIPSTTLTEDGYIFNLPEKTFPLPTKPAVLAMPSTQAPFRPQPTTAVPASRPTIEYLPPSTTQHPSYEKVQTSRRPVYLPPSPATESASSLIPKIRPRPEPRPQPTRRPTNEYLPPAAANEIPRFEPDRAPQPSNQKPIYRGEDQLSPQIFPTPQPANVPKHFAKCASALVCTSENFCNAIGVLSETPVELSPMEAAFRVPLTDCLQTENGSPGKCCRDPNYVDPWPVNLAGVCATRNKRTKPTGVKDLDANFAEIPWQAMILRESSKTLICGGAIIGDQFVLSSASCVNGLPVTDIRVKAGEWELGSTNEPLPFQLTGVKTVDVHPDYDPSTNSHDLAIIRLERRLEFASHIQPICISDEDPKDSEQCFTSGWGKQALSIHEEGALMHVTDTLPQARSECSADSSSVCSATKFDSCQFDVGSALACGSGSSVRLKGIFAGENSCGEGQTVRFAKPDIKWINTAFAENNKPLLLKRF
What is the function of this protein?
Inactive serine protease that plays a role in germ-band retraction and dorsal closure morphogenesis in embryogenesis; contributes to amnioserosa attachment and epithelial apico-basal polarity by regulating the localization of laminin LanA on the apical side of the amnioserosa epithelium (PubMed:28628612, PubMed:20379222).  Contributes to epithelial morphogenesis probably by regulating the bsk/JNK pathway, as part of a negative-feedback loop, and by modulating the cross-talk between the Egfr, bsk/JNK and dpp signal transduction pathways (PubMed:28628612, PubMed:20379222).  In larval development, antagonizes the morphogenetic movements controlled by the bsk/JNK signaling including male genitalia formation and thorax development (PubMed:20379222, PubMed:20530545, PubMed:25737837).
What are the official names of this protein?
Inactive serine protease scarface.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: TYPH_SALTY
Sequence: MFLAQEIIRKKRDGHALSDEEIRFFINGIRDNTISEGQIAALAMTIFFHDMTMPERVSLTMAMRDSGTVLDWKSLNLNGPIVDKHSTGGVGDVTSLMLGPMVAACGGYVPMISGRGLGHTGGTLDKLEAIPGFDIFPDDNRFREIIQDVGVAIIGQTSSLAPADKRFYATRDITATVDSIPLITGSILAKKLAEGLDALVMDVKVGSGAFMPTYELSEALAEAIVGVANGAGVRTTALLTDMNQVLASSAGNAVEVREAVQFLTGEYRNPRLFDVTMALCVEMLISGQLAKDDAEARAKLQAVLDNGKAAEVFGRMVAAQKGPSDFVENYDKYLPTAMLSKAVYADTEGFISAMDTRALGMAVVSMGGGRRQASDTIDYSVGFTDMARLGDSIDGQRPLAVIHAKDEASWQEAAKAVKAAIILDDKAPASTPSVYRRITE
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: GCH1_CLOK5
Sequence: MDENKIKDAVRMIIEAIGENPEREGLAETPDRIARMYTEIFSGLKEKPEEHLKKVFTVNNDDIVLEKDIQFYSMCEHHFMPFYGKTHVAYIPNGKVVGLSKLARTVEVFAKRLQLQERMTVQIADSIMDYLKVKGVMVVIEAEHMCMTMRGIKKPGSKTVTVATRGIFKNKIEFRNQVYEMIKMK
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.