PharMolix/UniProtQA huggingface dataset:
Protein: ILVD_PELUB
Sequence: MAKFNKKKLPSRHTSLGADRAPHRSFYYAMGETEKDVAKPFVGVVSTWNEAAPCNIALMRQAQSVKKGVRASGGTPREFCTITVTDGIAMGHEGMKSSLISREVIADSTELTVRGHCYDALVGIAGCDKSLPALMMAMVRLNVPSVFIYGGSILPGQYKGKDVTVVDVFEAVGKHSAGKMSAKELRKLELVACPSAGACGGQFTANTMACVSEAIGLALPYSAGTPAPYEERDKYALLSGKTVMNLLQKNIRPRDIVTKKSLENAATIVAATGGSTNAALHLPAIANEIGIKFDLMDVAKIFKKTPYLADLKPGGKYVAKDMWLAGGVPMLLKTLFDGGFIHGDCMTVTGKTMKQNLKNIKFNPKQKVLRAYDNPLSPDGGVVGLKGNLAPDGGIVKIAGLKKLQFTGKARCFDNEEAAMACVQKKKYKAGDVIIIRYEGPVGGPGMREMLSTTGAIYGQGMGEKVALITDGRFSGATRGFCVGHVGPEAALGGPLALLRNGDVIDIDAKKGTINVRLTKSQLATRHKKWKAKKSSFGSGTIWKYAQTVGPAYLGAPTHPGKRKEVKVYADI
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: SYE_LEPCP
Sequence: MTQVSTPVRTRFAPSPTGFIHLGNIRSALYPWAFARATGGTFVLRIEDTDVERSSQAAVDVIVEGMKWLGLDHDEGPFFQMQRMARYKEVLAQLVARGQVYPCYMSMTELDALRERQMANKEKPRYDGTWRPEPGKVLPAVPEGVQPVLRFRTPQGGSVIWDDKVKGRIEISNDELDDLVIARPDGTPTYNFCVVVDDIDMAITHVIRGDDHVNNTPRQIHIFRALGQEPPVYAHLPTVLNEQGEKMSKRHGAKPVTQYREEGFLADAVVNYLARLGWSHGDDEIFSRAQLIEWFNLDHLGKSAGQYDEAKLRWVNSQHMKLCDNGVLAGLVAEQFARRELLVPVDERLARMCALFKDRCSTTVELADWLSMYFVPIQASEQDLAAHVTDAVRPALQTLRDKLAALASWDKASISLCIKETIATHALKMPLLAVPVRVLVTGRAQTPSVDAVLELFQQEIVLKRLQSV
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPW82_ARATH
Sequence: MIAEVAAGGALGLALSVLHEAVKRAKDRSVTTRFILHRLEATIDSITPLVVQIDKFSEEMEDSTSRKVNKRLKLLLENAVSLVEENAELRRRNVRKKFRYMRDIKEFEAKLRWVVDVDVQVNQLADIKELKAKMSEISTKLDKIMPQPKFEIHIGWCSGKTNRAIRFTFCSDDS
What is the function of this protein?
Disease resistance (R) protein that induces localized, salicylic acid-dependent defenses (PubMed:11141561).  Confers resistance to powdery mildew (e. g.  Erysiphe cichoracearum UCSC1) (PubMed:11141561, PubMed:15155802, PubMed:17565954).
What are the official names of this protein?
Protein RESISTANCE TO POWDERY MILDEW 8.2, AtRPW8.2.
What is the protein family that this protein belongs to?
Belongs to the plant RPW8 protein family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CEMA_POPTR
Sequence: MEKKAFIPLLYLTSIVFLPWWVSFSFNKSLGSWIINWWNTSKSETFLNDIQEKSILEKLIEFEELFLLDEMIKEYPETHLQKFRIGIHKETIQLIKMHNADRIDTILHFSTNIICFVILSGYSFLVNEELFILNSWVQEFIYNLSDTIKALSILLLTDLCIGFHSPHGWELMISSFYKDFGFAHNDQIISGLVSTFPVIFDTIFKYWIFRYLNRVSPSLVVIYHSMND
What is the function of this protein?
May be involved in proton extrusion.  Indirectly promotes efficient inorganic carbon uptake into chloroplasts.
What are the official names of this protein?
Chloroplast envelope membrane protein.
What is the protein family that this protein belongs to?
Belongs to the Cema family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: KC1AL_HUMAN
Sequence: MTNNSGSKAELVVGGKYKLVRKIGSGSFGDVYLGITTTNGEDVAVKLESQKVKHPQLLYESKLYTILQGGVGIPHMHWYGQEKDNNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFLHRDIKPDNFLMGTGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKHLIGTVRYASINAHLGIEQSRRDDMESLGYVFMYFNRTSLPWQGLRAMTKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEVPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQAASSSGQGQQAQTQTGKQTEKNKNNVKDN
What is the function of this protein?
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates.  It can phosphorylate a large number of proteins.  Participates in Wnt signaling (By similarity).
What are the official names of this protein?
Casein kinase I isoform alpha-like, CKI-alpha-like, CK1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTR1A_SHEEP
Sequence: MAGRLWGSPGGTPKGNGSSALLNVSQAAPGAGDGVRPRPSWLAATLASILIFTIVVDIVGNLLVVLSVYRNKKLRNAGNVFVVSLAVADLLVAVYPYPLALASIVNNGWSLSSLHCQLSGFLMGLSVIGSVFSITGIAINRYCCICHSLRYGKLYSGTNSLCYVFLIWTLTLVAIVPNLCVGTLQYDPRIYSCTFTQSVSSAYTIAVVVFHFIVPMLVVVFCYLRIWALVLQVRWKVKPDNKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLVVASDPASMAPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRQEYRKIIVSLCTTKMFFVDSSNHVADRIKRKPSPLIANHNLIKVDSV
What is the function of this protein?
High affinity receptor for melatonin.  Likely to mediate the reproductive and circadian actions of melatonin.  The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.
What are the official names of this protein?
Melatonin receptor type 1A, Mel-1A-R, Mel1a receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KTHY_PROMP
Sequence: MRGKFIVIEGIDGCGKTTQIDEISKWIPTSGLLRGKQKLVKTREPGGSLLGKKIRNLILDNHKDNKPSSLAELLLYSADRAEHISKTISPALENQDWVLSDRFCDSTLAYQGYGRNINLEIIKNIESIVCQGESPDLTIFLEISAEESVLRREKFIPDRMESEGIKFLEKVNEGFKLIAKEKNWTTISALQDINTITNEIKETLLKKFSRVNND
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: ATPB_BUXMI
Sequence: MRINPTTSGPEVSTLEEKNLGRIAQIIGPVLDVAFPPGKMPNIYNALVVKGRDTVGQQINVTCEVQQLLGNNRVRAVAMSATDGLTRGMEVIDTRAPLSVPVGGATLGRIFNVLGEPVDNLGPVDTRTTSPIHRSAPAFIQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEQNIAESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPRIVGEEHYETAQRVKQTLQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFQLILSGELDGLPEQAFYLVGNIDEATAKAMNLEVESKLKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: DAP_BRUC2
Sequence: MPNIDLPTLEAFVHAIPQNYKGPGGAVAVVRNGEIVLRHAWGFADLAARKAMTPETRMPICSVSKQFTCAVLLDCIGEPEMLDSALAAYLDQFEDGRPAVRDLCNNQSGLRDYWALTVLCGAAPEGIFLPDQAQNLLRRLKTTHFAPGTHYSYCNGNFRILADLIEQHTGRSLADLLAERIFAPAAMKTAELIPDTALFNECTGYEGDTVRGFLPAINRIHWLGDAGICASLDDMIAWEQFIDRTRHDENGLYRRLSSPQTFADGAPAPYGFGLKFEETGGKRLTGHGGALRGWRCQRWHCADERISTIVMFNFEGNASDAALKMMNAALGIPPAKPVRAQANPGWFGSWLNPETGLVLSLEDAGGGRMKARFGTGPEIMDISGENEAQSSMTTLRRDGDMIHLARKDENLHLAMHRLKGEARQDIAGRYRSDELEADLLLVSEGGAIYGAFEGFLGKSDMYPLYAAGPDVWLLPVQRSMDAPSPGEWKLVFHRDAAGRITGVTVGCWLARGVEYKRL
What is the function of this protein?
Hydrolyzes N-terminal residues in D-amino acid-containing peptides.
What are the official names of this protein?
D-aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S12 family.
Protein: LSPA_THEVB
Sequence: MSSRHFKIKNSLFWWVAGLALASDRLTKAWIVATYALTVPPQTTPIIPGVFHITYVTNTGAAFSLFANGSIWLRWLSLIVSLGLITWAILGPRLDRWQQVGYGCLLGGALGNGIDRFLTGEVVDFLDFRWIQFPVFNVADIAINIGIVCLLWSAWHPR
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CAPP_ECOL6
Sequence: MNEQYSALRSNVSMLGKVLGETIKDALGEHILERVETIRKLSKSSRAGNDANRQELLTTLQNLSNDELLPVARAFSQFLNLANTAEQYHSISPKGEAASNPEVIARTLRKLKNQPELSEDTIKKAVESLSLELVLTAHPTEITRRTLIHKMVEVNACLKQLDNKDIADYEHNQLMRRLRQLIAQSWHTDEIRKLRPSPVDEAKWGFAVVENSLWQGVPNYLRELNEQLEENLGYKLPVEFVPVRFTSWMGGDRDGNPNVTADITRHVLLLSRWKATDLFLKDIQVLVSELSMVEATPELLALVGEEGAAEPYRYLMKNLRSRLMATQAWLEARLKGEELPKPEGLLTQNEELWEPLYACYQSLQACGMGIIANGDLLDTLRRVKCFGVPLVRIDIRQESTRHTEALGELTRYLGIGDYESWSEADKQAFLIRELNSKRPLLPRNWQPSAETREVLDTCQVIAEAPQGSIAAYVISMAKTPSDVLAVHLLLKEAGIGFAMPVAPLFETLDDLNNANDVMTQLLNIDWYRGLIQGKQMVMIGYSDSAKDAGVMAASWAQYQAQDALIKTCEKAGIELTLFHGRGGSIGRGGAPAHAALLSQPPGSLKGGLRVTEQGEMIRFKYGLPEITVSSLSLYTGAILEANLLPPPEPKESWRRIMDELSVISCDLYRGYVRENKDFVPYFRSATPEQELGKLPLGSRPAKRRPTGGVESLRAIPWIFAWTQNRLMLPAWLGAGTALQKVVEDGKQSELEAMCRDWPFFSTRLGMLEMVFAKADLWLAEYYDQRLVDKALWPLGKELRNLQEEDIKVVLAIANDSHLMADLPWIAESIQLRNIYTDPLNVLQAELLHRSRQAEKEGQEPDPRVEQALMVTIAGIAAGMRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: GDF6_BOVIN
Sequence: MDTSRVLLSAVFLISFLWDLPGFQQASISSSSSSAELGSAKGMRSRKEGRMPRAPRENATAREPLDRQEPPPRPQEEPQRRPPQQPEAREPPGRGPRVVPHEYMLSIYRTYSIAEKLGINASFFQSSKSANTITSFVDRGLDDLSHTPLRRQKYLFDVSTLSDKEELVGAELRLFRQAPAAPWGPPAGPLRLQLFACQSPLLLEARSLDPQGAPRPGWEVFDVWRGLRPQPWKQLCLELRAAWGGEPGAAEDEARAPGPQQPPPPDLRSLGFGRRVRTPQERALLVVFSRSQRKTLFAEMREQLGSATEVVGPGGGAEGSGPPPPPPPPPPSGTPDAGLWSPSPGRRRRRTAFASRHGKRHGKKSRLRCSKKPLHVNFKELGWDDWIIAPLEYEAYHCEGVCDFPLRSHLEPTNHAIIQTLMNSMDPGSTPPSCCVPTKLTPISILYIDAGNNVVYKQYEEMVVESCGCR
What is the function of this protein?
Growth factor that controls proliferation and cellular differentiation in the retina and bone formation.  Plays a key role in regulating apoptosis during retinal development.  Establishes dorsal-ventral positional information in the retina and controls the formation of the retinotectal map.  Required for normal formation of bones and joints in the limbs, skull, digits and axial skeleton.  Plays a key role in establishing boundaries between skeletal elements during development.  Regulation of GDF6 expression seems to be a mechanism for evolving species-specific changes in skeletal structures.  Seems to positively regulate differentiation of chondrogenic tissue through the growth factor receptors subunits BMPR1A, BMPR1B, BMPR2 and ACVR2A, leading to the activation of SMAD1-SMAD5-SMAD8 complex.  The regulation of chondrogenic differentiation is inhibited by NOG.  Also involved in the induction of adipogenesis from mesenchymal stem cells.  This mechanism acts through the growth factor receptors subunits BMPR1A, BMPR2 and ACVR2A and the activation of SMAD1-SMAD5-SMAD8 complex and MAPK14/p38.
What are the official names of this protein?
Growth/differentiation factor 6, GDF-6, Bone morphogenetic protein 13, BMP-13, Cartilage-derived morphogenetic protein 2, CDMP-2.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: PLAS_SYNY3
Sequence: MSKKFLTILAGLLLVVSSFFLSVSPAAAANATVKMGSDSGALVFEPSTVTIKAGEEVKWVNNKLSPHNIVFAADGVDADTAAKLSHKGLAFAAGESFTSTFTEPGTYTYYCEPHRGAGMVGKVVVE
What is the function of this protein?
Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I.
What are the official names of this protein?
Plastocyanin.
What is the protein family that this protein belongs to?
Belongs to the plastocyanin family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Lumenal side. Note=Loosely bound to the thylakoid inner membrane surface (PubMed:9466912).
Protein: ENDUD_XENLA
Sequence: MKVYFVFLCLLPSLISGASILPEPRKDVRASASNAEIQSLAEQFYAADTNKAASGDITLNLQYKASSTQTSSGTDFASQKLFNYVNEAKLFARPTFARLVDLLDNYVHTTGTAESVPTAEVNEQNAFIDEIFKTSIITKLSDFFISKGYYSSAASFKTDLKEMWFGLYTRTSGPLDSSGFEHVFHGEIHKGKISGLHNWVRLYLLEKSGQVNYLSYSSDGVWNGYPDIYAFQLKWSTYLKTLGSFFIGSSPEFDIAMYTLCYVTRPDSLCSVKMGGSIFQIQTYTWANSTYGNGKRYVASSYPNI
What is the function of this protein?
Endoribonuclease that cleaves single-stranded RNAs at 5' of uridylates and releases a product with a 2',3'-cyclic phosphate at the 3'-end.
What are the official names of this protein?
Uridylate-specific endoribonuclease D, Protein endoU-D, XendoU-D.
What is the protein family that this protein belongs to?
Belongs to the ENDOU family.
What are the subcellular locations of this protein?
Secreted.
Protein: KDSB_CHLL2
Sequence: MNAVILIPARLDSSRLPKKMLADLDGEPLIVRTWRQALLSNHAVRVVVATDSPEIAGALEAYGAEVMMTSPHARCGTERIAEAARSIDADVFLNLQGDEPLIDPRNIDLCLEPFLADNPPDCSTLVYPLLPEDFQQIDDPNVVKVVLDRNGNALYFSRSPVPFQREVYAATQFYRHIGLYAFSAEVLQHYASLPPSMLEKAESLEQLRLLENGFSIRCVTTTVDHPGVNTPEDLDLVRRMLRRSAGR
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPPB_ECOL6
Sequence: MLQFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVMIMAGERGISPERHAQLLAELGLDKPMWQQYLHYIWGVMHGDLGISMKSRIPVWEEFVPRFQATLELGVCAMIFATAVGIPVGVLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSVHWNLTPVSGRVSDMVFLDDSNPLTGFMLIDTAIWGEDGNFIDAVAHMILPAIVLGTIPLAVIVRMTRSSMLEVLGEDYIRTARAKGLTRMRVIIVHALRNAMLPVVTVIGLQVGTLLAGAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMIILVNLLVDLLYGVVNPRIRHKK
What is the function of this protein?
Part of the ABC transporter DppABCDF involved in dipeptide transport.  Responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Dipeptide transport system permease protein DppB.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RAA6B_ARATH
Sequence: MAEESYDEECDYLFKAVLIGDSAVGKSNLLSRFSRDEFRLDSKPTIGVDFAYRNVRVGDKTIKAQIWDTAGQERFRAITSSYYRGALGALLIYDITRRITFKNIEKWLSELRGFSSPETVVVLVGNKSDLGQSREVEEEEGKTLAESEGLYFLETSALENQNVEEAFLSMIGRIHEVLTQKIVLDNRLNGDGNNESNGAVVPPGKEIVNIHEVTATRPLSTSLSNCCYK
What is the function of this protein?
Intracellular vesicle trafficking and protein transport.
What are the official names of this protein?
Ras-related protein RABA6b, AtRABA6b.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: DLDH_PONAB
Sequence: MQSWSRVYCSLAKRGHFNRISHGLQGLSAVPLRTYADQPIDADVTVIGSGPGGYVAAIKAAQLGFKTVCVEKNETLGGTCLNVGCIPSKALLNNSHYYHMAHGKDFASRGIEMSEVRLNLDKMMEQKSTAVKALTGGIAHLFKQNKVVHVNGYGKITGKNQVTATKADGGTQVIDTKNILIATGSEVTPFPGIMIDEDTIVSSTGALSLKKVPEKMVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGGVGIDMEISKNFQRILQKQGFKFKLNTKVTGATKKSDGKIDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNLGLEELGIELDPRGRIPVNTRFQTKIPNIYAIGDVVAGPMLAHKAEDEGIICVEGMAGGAVHIDYNCVPSVIYTHPEVAWVGKSEEQLKEEGIEYKVGKFPFAANSRAKTNADTDGMVKILGQKSTDRVLGAHILGPGAGGMVNEAALALEYGASCEDIARVCHAHPTLSEAFREANLAASFGKSINF
What is the function of this protein?
Lipoamide dehydrogenase is a component of the glycine cleavage system as well as an E3 component of three alpha-ketoacid dehydrogenase complexes (pyruvate-, alpha-ketoglutarate-, and branched-chain amino acid-dehydrogenase complex).  The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion.  A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A.  In monomeric form may have additional moonlighting function as serine protease (By similarity).  Involved in the hyperactivation of spermatazoa during capacitation and in the spermatazoal acrosome reaction (By similarity).
What are the official names of this protein?
Dihydrolipoyl dehydrogenase, mitochondrial, Dihydrolipoamide dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Nucleus. Cell projection, cilium, flagellum. Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Mainly localizes in the mitochondrion. A small fraction localizes to the nucleus, where the 2- oxoglutarate dehydrogenase complex is required for histone succinylation.
Protein: HSLU_AZOSB
Sequence: MTQMTPPEIVSELDKHIVGQARAKKAVAIALRNRWRRARIDEPLRSEITPKNILMIGPTGVGKTEIARRLARLANAPFIKVEATKFTEVGYVGRDVDTIIRDLVEIAIKDGRERAMRVVRDRALDAAEDRVLDVLLPPARPVGFSEPAQPQDSATRQKFRKKLREGELDDKEVEIEVASAPMQAEIFAPPGMEELTQQIQGMFQNLGNSRKKLRKLPIREALKLLADEEAARLINDEEVKTEALRAVEQNGIVFLDEVDKIAARADAHGADVSRQGVQRDLLPLVEGTTISTKYGMIKTDHILFIASGAFHLSKPSDLIPELQGRFPIRVELESLSVEDFERILTSTDACLTRQYEALLATDGVTLSFTPEGIRRLAEIAYQVNEKTENIGARRLYTVMEKLLEEVSFEAGKVGVDKLTVDAAYVDARLEVLAQREDLARYVL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_RHORT
Sequence: MSQSVLRLVDKDTMDKQKALEAAVGQIERAFGKGSIMKLGQRGSVVDIESISTGSLGLDIALGIGGLPRGRIVEIYGPESSGKTTLALHVVAEAQKKGGQCAFVDAEHAFDPLYARKLGVSLDDLLVSQPDTGEQALEIADTLVRSGAIDVLVIDSVAALVPKAELEGDMGDSHVGLQARLMSQALRKLTGTVSRSNTLIIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRIGAVKDKEEVVGNQTRVKVVKNKVAPPFKVVEFDIMYGEGISKLGEMLDLGVKANIIEKSGAWFSYNSTRIGQGRENAKQFLRDNPAMAEEIENAVRANAGLIAEEMIGGPGGEDDDAGGAAGVGDEA
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASSY_SYNS3
Sequence: MGRATKVVLAYSGGVDTSVCIPYLKQEWGVEEVITFAADLGQGDELEPIRLKALEAGATQSLVGDLIKPFIEEFAFPAIRANALYEGRYPLSTALARPLIARRLVEVAREVGADAVAHGCTGKGNDQVRFDVAIASLAPDLKVLTPAREWGMSREETIAYGERFGMPSPVSKKSPYSIDLNLLGRSIEAGPLEDPMVAPPEEVFAMTRSVDQTPNDAEEIEIQFEGGNPVAINGKRLEPVSLIREANLLAGTHGIGRLDMIENRVVGIKSREIYETPGLLLLIQAHQELESLTLAADVLRTKRQLEMQWADLVYQGLWFGPLKEALDGFMDRTQIHVNGVVRLKLHKGNATVTGRASTDNSLYIPEMASYGSEDKFDHRAAEGFIYVWGLPTRLWAAKHRR
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA2BI_GLOSA
Sequence: NLLQFNKMIKVETGKNAIPFYAF
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that shows presynaptic neurotoxicity and low myotoxicity.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Basic phospholipase A2 intermexin, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PAT_ECOSE
Sequence: MNRLPSSASALACSAHALNLIEKRTLDHEEMKALNREVIEYFKEHVNPGFLEYRKSVTAGGDYGAVEWQAGGLNTLVDTQGQEFIDCLGGFGIFNVGHRNPVVVSAVQNQLAKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGTESVEAALKLAKAYQSPRGKFTFIATSGAFHGKSLGALSATAKSTFRKPFMPLLPGFRHVPFGNIEAMRTALNECKKTGDDVAAVILEPIQGEGGVILPPPGYLTAVRKLCDEFGALMILDEVQTGMGRTGKMFACEHENVQPDILCLAKALGGGVMPIGATIATEEVFSVLFDNPFLHTTTFGGNPLACAAALATINVLLEQNLPAQAEQKGDMLLDGFRQLAREYPDLVQEARGKGMLMAIEFVDNEIGYNFASEMFRQRVLVAGTLNNAKTIRIEPPLTLTIEQCELVIKAARKALAAMRVSVEEA
What is the function of this protein?
Catalyzes the aminotransferase reaction from putrescine to 2-oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline.  This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate (gamma-aminobutyrate or GABA) via 4-aminobutanal.  Also functions as a cadaverine transaminase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
What are the official names of this protein?
Putrescine aminotransferase, PAT, PATase, Cadaverine transaminase, Diamine transaminase, Putrescine transaminase, Putrescine--2-oxoglutaric acid transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. Putrescine aminotransferase subfamily.
Protein: GPMA_CLAMS
Sequence: MAEPRTLVLLRHGNSDWNQKNLFTGWVDVELSEQGVAEGQRAGELLAESGILPDVLHTSVLIRAIDTANIALKRAGRSWIPVQRTWRLNERHYGALQGKDKAQTLAEYGPEQFATWRRSFDVPPPPIADDDEYSQSADPRYADLGDTLPRTECLKDVIERMLPYWESDIQPDLASGRTVLVTAHGNSLRALVKHLDGISDADIAELNIPTGIPLVYRLDEDFRPIVPGGEYLDPEAAAAGAAAVAAQGSKK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: ECFA1_STAAN
Sequence: MEDKNSVIVFKNVSFQYQSDASFTLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITDDNFEKLRKDIGIVFQNPDNQFVGSIVKYDVAFGLENHAVPHDEMHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIASVLALNPSVIILDEATSMLDPDARQNLLDLVRKVKSEHNITIISITHDLSEAMEADHVIVMNKGTVYKEGTATEIFDHAEELTRIGLDLPFPIKINQMLGHQTSFLTYEGLVDQL
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA1, ECF transporter A component EcfA1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.