PharMolix/UniProtQA huggingface dataset:
Protein: FADB_ECO55
Sequence: MLYKGDTLYLDWLEDGIAELVFDAPGSVNKLDTATVASLGEAIGVLEQQSDLKGLLLRSNKAAFIVGADITEFLSLFLVPEEQLSQWLHFANSVFNRLEDLPVPTIAAVNGYALGGGCECVLATDYRLATPDLRIGLPETKLGIMPGFGGSVRMPRMLGADSALEIIAAGKDVGADQALKIGLVDGVVKAEKLVEGAKAVLRQAINGDLDWKAKRQPKLEPLKLSKIEATMSFTIAKGMVAQTAGKHYPAPITAVKTIEAAARFGREEALNLENKSFVPLAHTNEARALVGIFLNDQYVKGKAKKLTKDVETPKQAAVLGAGIMGGGIAYQSAWKGVPVVMKDINDKSLTLGMTEAAKLLNKQLERGKIDGLKLAGVISTIHPTLDYAGFDRVDVVVEAVVENPKVKKAVLAETEQKVRPDTVLASNTSTIPISELANALERPENFCGMHFFNPVHRMPLVEIIRGEKSSDETIAKVVAWASKMGKTPIVVNDCPGFFVNRVLFPYFAGFSQLLRDGADFRKIDKVMEKQFGWPMGPAYLLDVVGIDTAHHAQAVMAAGFPQRMQKDYRDAIDALFDANRFGQKNGLGFWRYKEDSKGKPKKEEDAAVEDLLAEVSQPKRDFSEEEIIARMMIPMVNEVVRCLEEGIIATPAEADMALVYGLGFPPFHGGAFRWLDTLGSAKYLDMAQQYQHLGPLYEVPEGLRNKARHNEPYYPPVEPARPVGDLKTA
What is the function of this protein?
Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle.  Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA.  It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
Protein: RNPA_BORBR
Sequence: MPRATLPAEARLHRPSEFAAALKGRRLARGAFFIVSASPCAPADDQPARARLGLVIAKRFAARAVTRNTLKRVIREAFRARRLALPAQDYVVRLHSKLTPASLTALKRSARAEVDAHFTRIAR
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: LEU1_HALH5
Sequence: MRKISVFDTTLRDGEQSAGVNLNFEEKMEIAKQLERLGVDIIEAGFPASSQGDFQSVKAIAETVKGSSVTGLARSVQKDIDAAWEALKSAEEPRIHLFIATSPIHMEHKLRMTPEQVIEKAVESVKYAASRFKHVQWSAEDASRSDFPFLAQIIEAVIQAGATVINLPDTVGYTTPQEIKRMFQYMKQNVPSIDKVSLSTHNHDDLGMAVANSLAAIQGGADQVECTINGIGERAGNASLEEIAVALNIRKDHYETETGLILKEIKRTSSLVSKLTGMVVPNNKAVVGANAFAHESGIHQDGVLKNKQTYEIITPEMVGVSSNSMVLGKHSGRHAFKTKVQELGFTGTDEQLNNIFKAFKDLADKKKEITEDDLFALMTEQTVGGETNHYELQTLQVNYGSNLTNTATITMKLPSGEVAEEAATGSGSVEAIYNTLERLLDAPVKLLDYRIQSITGGRDALADVYVQMDYQGVVSSGRGTAHDVLEASAKAYLNAVNRTINRKKYAEVYGSKVEV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: VPB18_MYCTO
Sequence: MSTTIVAGVIQGHLPVILPTRRRARDLGHTTALFRAQTLQCIYLSIEYLYVCSMSRRTTIDIDDILLARAQAALGTTGLKDRVDAALRAAVR
What is the function of this protein?
Putative antitoxin component of a possible type II toxin-antitoxin (TA) system.  The cognate toxin is VapC18 (By similarity).
What are the official names of this protein?
Putative antitoxin VapB18.
Protein: MIR1_MHV68
Sequence: MDSTGEFCWICHQPEGPLKRFCGCKGSCAVSHQDCLRGWLETSRRQTCALCGTPYSMKWKTKPLREWTWGEEEVLAAMEACLPLVLIPLAVLMIVMGTWLLVNHNGFLSPRMQVVLVVIVLLAMIVFSASASYVMVEGPGCLDTCTAKNSTVTVNSIDEAIATQQPTKTDLGLARETLSTRFRRGKCRSCCRLGCVRLCCV
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates ubiquitination of host surface class I (MHC-I) H-2D(b)/H2-D1 and H-2K(b)/H2-K1 molecules before they exit the endoplasmic reticulum, leading to their degradation by the endoplasmic reticulum-associated degradation (ERAD) system, thus blocking the immune detection of virus-infected cells.  Mediates ubiquitination of lysine, as well as serine and threonine residues present in the cytoplasmic tail of surface class I molecules.  Promotes ubiquitination of hydroxylated serine or threonine residues via ester bonds instead of the classical isopeptide linkage.
What are the official names of this protein?
E3 ubiquitin-protein ligase MIR1, MK3, Modulator of immune recognition 1 homolog, ORF K3, RING-type E3 ubiquitin transferase MIR1.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RS2_STACT
Sequence: MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQKTVKKVDEAYNFLKQVSEDGGKVLFVGTKKQAQESIKNEAERAGQFYVNQRWLGGILTNYKTISKRVKRISEIEKMEEDGLFEVLPKKEVVEIKKEYDRLIKFLGGIRDMKSMPQALFVVDPRKERNAIAEARKLHIPIVGIVDTNCDPDEIDYVIPANDDAIRAVKLLTGKMADAVLEGQQGVSNEEVAAEQNIDLNEDEVVEVEEVKETSVESN
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: NSF1C_HUMAN
Sequence: MAAERQEALREFVAVTGAEEDRARFFLESAGWDLQIALASFYEDGGDEDIVTISQATPSSVSRGTAPSDNRVTSFRDLIHDQDEDEEEEEGQRFYAGGSERSGQQIVGPPRKKSPNELVDDLFKGAKEHGAVAVERVTKSPGETSKPRPFAGGGYRLGAAPEEESAYVAGEKRQHSSQDVHVVLKLWKSGFSLDNGELRSYQDPSNAQFLESIRRGEVPAELRRLAHGGQVNLDMEDHRDEDFVKPKGAFKAFTGEGQKLGSTAPQVLSTSSPAQQAENEAKASSSILIDESEPTTNIQIRLADGGRLVQKFNHSHRISDIRLFIVDARPAMAATSFILMTTFPNKELADESQTLKEANLLNAVIVQRLT
What is the function of this protein?
Reduces the ATPase activity of VCP (By similarity).  Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis (By similarity).  May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER) (By similarity).  Inhibits the activity of CTSL (in vitro) (PubMed:15498563).  Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A during mitotic progression by promoting AURKA removal from centrosomes in prophase (PubMed:23649807).  Also, regulates spindle orientation during mitosis (PubMed:23649807).
What are the official names of this protein?
NSFL1 cofactor p47, UBX domain-containing protein 2C, p97 cofactor p47.
What is the protein family that this protein belongs to?
Belongs to the NSFL1C family.
Protein: Y749_STAA9
Sequence: MENKYTHGVLFYHEHSGLKNINQGIGEVTTALSSICKHLSIQLSENEGDIIKYCQEIKTKNYAKDVDILFILGGDGTVNELINGVMSHDLQLPIGILPGGTFNDFTKTLNIAPNHKQASEQMISAQVGTYDVIKINNQYALNFVGLGLIVQNAENVQDGSKDIFGKLSYIGSTVKTLLNPTQFNYQLSIDDKTYSGETTMILTANGPFIGGSRIPLTDLSPQDGELNTFIFNEQSFSILNDIFKKRDSMNWNEITQGIEHIPGKKISLTTDPAMKVDIDGEISLETPIDIEVIPNAIQLLTVNDL
What is the function of this protein?
May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG).
What are the official names of this protein?
Putative lipid kinase SaurJH9_0749.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol/lipid kinase family.
Protein: ACCD_BACSU
Sequence: MLKDIFTKKKKYASVPSDQAKHDVPEGIMTKCPKCKKIMLTKELDKNMRVCMNCDYHFPMNAKQRIESLMDEQSFEEFNQGMLSENPLGFPGYLEKLEKDREKTSLNEAVVTGKGTIGGHPAVVAVMDSSFRMGSMGSVVGEKITLAIEKAKADKVPFIIFTASGGARMQEGVLSLMQMAKTSSALKLFSEEQGLIISVMTHPTTGGVSASFASLGDYNFAEPGALIGFAGRRIIEQTIGEKLPEDFQTAEFLLKHGQLDAVIHRDDMKKTLENLLDMHQTGGDIEWLQD
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_STRPZ
Sequence: MKLQEIKDFVKELRGLSQEELAKKENELKKELFDLRFQAAAGQLEKTARLDEVKKQIARVKTVQSEMK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: DR8_HHV6U
Sequence: MWRSSNQRGVSRRRDKSMRKYTRHGNADRRQRAIASMASVRKKKPRSKNTYTGNISSLPPRPNHRNIHLRNPLSPRFYHGRVHTQTHRHAQPTHVVVAGGYVDGAYRGET
What are the official names of this protein?
Uncharacterized protein DR8.
Protein: SLDA_GLUTH
Sequence: MRRPYLLATAAGLALACSPLIAHAQFAPAGAGGEPSSSVPGPGNASEPTENSPKSQSYFAGPSPYAPQAPGVNAANLPDIESIDPSQVPAMAPQQSANPARGDWVAYGRDDHQTRYSPLSEITPENASKLKVAFVYHTGSYPRPGQVNKWAAETTPIKVGDGLYTCSAMNDIIKLDPATGKQIWRRNVDVKYHSIPYTAACKGVTYFTSSVVPEGQPCHNRLIEGTLDMRLIAVDAETGDFCPNFGHGGQVNLMQGLGESVPGFVSMTAPPPVINGVVVVNHEVLDGQRRWAPSGVIRGYDAESGKFVWAWDVNNSDDHSQPTGNRHYSRGTPNSWATMTGDNEEGLVYVPTGNSAADYYSALRSDAENKVSSAVVAIDVKTGSPRWVFQTAHKDVWDYDIGSQATLMDMPGPDGQTVPALIMPTKRGQTFVLDRRTGKPILPVEERPAPSPGVIPGDPRSPTQPWSVGMPALRVPDLKETDMWGMSPIDQLFCRIKFRRANYVGEFTPPSVDKPWIEYPGYNGGSDWGSMSYDPQSGILIANWNITPMYDQLVTRKKADSLGLMPIDDPNFKPGGGGAEGNGAMDGTPYGIVVTPFWDQYTGMMCNRPPYGMITAIDMKHGQKVLWQHPLGTARANGPWGLPTGLPWEIGTPNNGGSVVTGGGLIFIGAATDNQIRAIDEHTGKVVWSAVLPGGGQANPMTYEANGHQYVAIMAGGHHFMMTPVSDQLVVYALPDAIKQ
What is the function of this protein?
Catalyzes the oxidation of glycerol to glycerone.  Also acts, more slowly, on a number of other polyols including D-sorbitol, D-arabinitol, D-mannitol, meso-erythritol, adonitol and propylene glycol.
What are the official names of this protein?
Glycerol dehydrogenase large subunit, D-arabitol dehydrogenase large subunit, ARDH, D-sorbitol dehydrogenase subunit SldA, SLDH, Gluconate/polyol dehydrogenase large subunit.
What is the protein family that this protein belongs to?
Belongs to the bacterial PQQ dehydrogenase family.
What are the subcellular locations of this protein?
Secreted.
Protein: SECA_RICAE
Sequence: MLSILKKLFGTANDRTVKKLFSEITKINSLEPAIQKLSDEELKNKTVEFKEKLKNGATLDDIVYEAFAVVREAAKRVCGMRHFDVQLIGGLILHRGMITEMRTGEGKTLVATLPAYLNALTGKGVHVVTVNDYLARRDSASMGKIYNFLGLSVGCIVGGMPDEVKRAAYNADITHATNNELGFDYLRDNMKYSLQERVLRPFNFAIIDEVDSILIDEARTPLVISGPVNDNAELYGKIDKIVRLLNASDFEKDEKLKTINLTETGITHIESLLSKESIIKPDTSLYDFENLTLVHYVNQALRAHNMFTVNVDYLVREGKVMIIDEFTGRVMEGRRYSEGLHQALEAKENVKIQNENQTLASITFQNYFRNYPKLSGMTGTAMTEAPELKDIYNLDVVAVPTHNKVTRLDLDDEIYGSKKEKYDAILKLIRDCYDRGQPILVGTISIEKSEELSSVLNKEKIPHKVLNAKFHEQEAFIIAQAGRFKAVTIATNMAGRGTDIMLGGNPEMLIEQLDKAHNYEAKVAEIKAQIAEEKKQVIEAGGLFVIGTERHESRRIDNQLRGRSGRQGDPGKTKFFLSLDDDLMRIFASDRISGVLRTLGLKDGEAIHHPMISRSLEKAQQKVEGHNYEMRKNLLRFDDVMNDQRKIIYEQRTEIIKSKDSHGFLNSTTEELAQKIVLTFMPVGSYREDWDIENLSVELHRVFSIKFDHNVVSKNDVTEEEITKTVIQMAHDIYKSKEEAYSSELMHNAVKYILLTTLDQVWKDHLYSLDHLRQGISLRAYGQKDPLSEYKREAFNLFEQMLNNLKELFIQTVYHFHIDLKNVQKEDVSLEYKKLQKNMRESREDPAFSKYNAGSSIETDLKPVVSRIDPKDRNPDDPTSWGRVSRNELCPCGSGKKYKYCHGANE
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: Y8238_DICDI
Sequence: MNKVVSINIAEILKSHATHKSLMVRNKNFLRSSNGSVPIYSNSILQPPTTATNNNNENNFNLVNDTIDDLELAIENAGGKQFW
What are the official names of this protein?
Uncharacterized protein DDB_G0267930.
Protein: XYLA_LISW6
Sequence: MTYFKQIEKINYEGVQSGNRFAFRHYNPEEVVLGKSMKEHLRFAVAYWHTMTQDGSDPFGAATNVRDVSGKTEMELARNRVEMFFEILEKLGVEYFCFHDVDIAPEGNSLQEFMRNLDEITDLIQDKMKQTGIKLLWNTANLFTHPRFLNGAASTNNADVYAFSAAQIKKGLDISKKLGGKNYVFWGGREGYESLLNTDMEFEQANMARMYKMAIRYANEIEHEVQFLIEPKPKEPTKHQYDFDAATTMAFLQKYGLENDFKLNLEANHATLAGHTFEHELNVARTYNALGSIDANQGDLLLGWDTDEFPTNIYDTTLTMYEILQNGGIAPGGINFDAKVRRTSFEMEDLLLAHIAGMDTYARGLKAAAKLTEDHFFDKIKEERYRSFKKGIGARILDNQEDFKSLTEYALAHDSIQNESSHIEYVKSRLNDYLV
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEND_ACTPJ
Sequence: MTVSTFNRTWAKVIVNALLRYGVKHFCIAPGSRSTPLTLEALQLQQNQQAQCHSHFDERGLGFFALGIAKVTNDPVAIIVTSGTAVANLYPAIIEASLTHHKLIVLSADRPPELIGCGANQAIPQQGIFADYPIAGVNLPKPAEHYNAGWLVATIEQACITQSQQGGVVHINAPFAEPLYEADENAINTHPWLKPIQSWLINPQTKWINSQTIQSEVSMHENWDYWRTKRGVIVVGKLPVEQGIGIKAWAETLGWCLITDVQSCVDANLPYADIWLSNNTVHQRLLQADIVIQFGGQIVSKRVNKFLEAFKGEFWQVDEYSDYLNPFAHHQTRFVAKAHHFLRVHPPLRQKPWLLEPLALSQFCAGFIEQQVGGSLNEASLAHHIEEVLATSGNLFIGNSLFVRLVDALCKLPEGYPVYTNRGASGIDGLIATMAGVAKGSGQPTVGIIGDISALHDLNSVSLLNKISHPCILFVINNSGGAIFDMLPVEAQAKEQFYRLSHNYEFAPIATMFGIEYIRPFTWADLKAKLKLAYGRKGVTIVEIKVNDQDGSNLYKSLVKQISQAEIA
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: RDGC_YERPG
Sequence: MLWFKNLMVYRLSREVSLSADEMEKQLSAFSFTPCGSQDMAKTGWVSPMGSHSDALTHTVNGQIVICVRKEEKILPSPVIKQELQDKIERLEGEQHRKLKKTEKDSLKDEVLHSLLPRAFSRFNQTFLWIDTVNDLIMVDAASAKRAEDTLALLRKSLGSLPVVPLTLENPIELTLTEWVRSKTLPAGFALMDEAELKAILEDGGVIRCKKQDLFSDEIAVHIEAGKLVTKLALDWQERIQLVLSDDGSLKRLKFADTLRDQNEDIDREDFAQRFDADFILMTSELAALIKNLIEALGGEAQH
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: AROQ_CLOAB
Sequence: MKILVINGPNINFLGIREKEIYGEGTYEDLCKFIKDEGSKIGIEVEVMQSNIEGEIINFLQAAYNKVDGIVINPGAYTHYSIAIYDAIKSINIPTVEVHISNIHTREEYRRKSVTAPACIGQICGFGFYGYVMGITALKNMLSK
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: CATL1_FASHE
Sequence: AVPDKIDPRESGYVTGVKDQ
What is the function of this protein?
Thiol protease that assists the parasite in burrowing through the gut wall and liver of its mammalian host.
What are the official names of this protein?
Cathepsin L1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: EFTS_AZOPC
Sequence: MAVTKLDVQYLRKMTGAGVMDCRNALREAEGNYDKAVEVIRKKGKVIASKRESREASEGCVLASSKQGFASIVAVKCETDFVAKGEDFVDMVRKILSVTLENKPRTIEDLNDLFIDGRRICEWITERSGISGEKMELGIYEYLEAPYTVAYVHPGNKLAVIVGFNQVIVKTQVARDVAMQIAAMNPISVDKNSIPAKIVEREEKIAREKAIEQGKPEAILDRIVNGALNKYYKEYTLLLQNFVKDPKITIDDYLKGQSRDLTVIEFRRINLNME
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFH5_ASPOR
Sequence: MADQQEKTASSAVPETQPPSQTAETTTQTTATPAPEVQTEQTQPTESGPSAANTTTEQPTNPPAAEASKENAAPAPAPAAEDAPSEPAPAQEQQKEEKPADNKPEYLAKNPALSQLFDRLPTVLSNSGHDEMWGVPLRDSSDVPTVNVLIKFLRANEGNVKLAEDQLTKALQWRKQTRPTALVEGRYSAKKFGGLGYLSTYKDADGKETVITWNIYGGVKDLGTTFGNVDEFINWRVALMELAVKDLKMDQATSVIDYEGEDPYQMIQVHDYLNVSFLRMNPSVKAATKKTIDVFATAYPELLREKFFVNVPSIMGWMFAAIKVFLSKNTTRKFHPISNGANLAREFPPAVKEQFPKVYGGSAPDLHEGARTVALEEDNEPAPAPAAPAEPTEEAKPEQEAPKQEPAPEAPKEEAIKEALVEAPKEEPKQPAVEEPAKTDTAVTTQETVAPAEAK
What is the function of this protein?
Non-classical phosphatidylinositol (PtdIns) transfer protein (PITP), which exhibits PtdIns-binding/transfer activity in the absence of detectable PtdCho-binding/transfer activity.  Regulates PtdIns(4,5)P2 homeostasis at the plasma membrane.  Heme-binding protein that may play a role in organic oxidant-induced stress responses.
What are the official names of this protein?
Phosphatidylinositol transfer protein sfh5, PITP sfh5.
What is the protein family that this protein belongs to?
Belongs to the SFH5 family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: LSRF_ENT38
Sequence: MADLDDIKDGKDFGIGTPQTNTPYTLKGCGALDWGMQSRLARIFNPKSNRTVMLAFDHGYFQGPTTGLERIDLSIAPLFAETDVLMCTRGILRSTVPPATNKPVVLRASGGNSILGELSNECVAVAMEDALRLNVCAVAAQVYIGSEFEHQSINNIIKLVDAGNRYGIPTLAVTGVGKEMARDARYFSLASRIAAEMGAQVVKTYFVEEGFEKVTASCPVPIVIAGGKKLPEHEALEMCFRAIDQGASGVDMGRNIFQSSAPLAMLKAVKKVVHENMSAREAFQFWQEEKQGEGQ
What is the function of this protein?
Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle.  Catalyzes the transfer of an acetyl moiety from 3-hydroxy-5-phosphonooxypentane-2,4-dione to CoA to form glycerone phosphate and acetyl-CoA.
What are the official names of this protein?
3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR7_PYRCJ
Sequence: MGFMELVYEGKAKAVYKTREGLLMVFKDEVTAGDGARRDKAPGKGALAAETSTLLFQYLQGRGVTTHYLMFVPPNAILVKPAQVPPLEVIVRFKAYGSYLKRMPKAKPLTPFAKPIVEFHYKDDSLHDPLILEDDVVEAGLLTAGELAAVKDMALRAASALRELYASVDCDFVDVKFEFGRVGGELVLVDEVSGDTFRLLCGGEHFDKEYYRKTGDAVGLVERYAKLLELTKLALSRQKV
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: IMDH_STAAS
Sequence: MWESKFAKESLTFDDVLLIPAQSDILPKDVDLSVQLSDKVKLNIPVISAGMDTVTESKMAIAMARQGGLGVIHKNMGVEEQADEVQKVKRSENGVISNPFFLTPEESVYEAEALMGKYRISGVPIVDNKEDRNLVGILTNRDLRFIEDFSIKIVDVMTQENLITAPVNTTLEEAEKILQKHKIEKLPLVKDGRLEGLITIKDIEKVIEFPNAAKDEHGRLLVAAAIGISKDTDIRAQKLVEAGVDVLVIDTAHGHSKGVIDQVKHIKKTYPEITLVAGNVATAEATKDLFEAGADIVKVGIGPGSICTTRVVAGVGVPQITAIYDCATEARKHGKAIIADGGIKFSGDIIKALAAGGHAVMLGSLLAGTEESPGATEIFQGRQYKVYRGMGSLGAMEKGSNDRYFQEDKAPKKFVPEGIEGRTAYKGALQDTIYQLMGGVRAGMGYTGSHDLRELREEAQFTRMGPAGLAESHPHNIQITKESPNYSF
What is the function of this protein?
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
What are the official names of this protein?
Inosine-5'-monophosphate dehydrogenase, IMP dehydrogenase, IMPD, IMPDH.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family.
Protein: HEPA_HHV7J
Sequence: MQMRGCVCHLGVYCVHNDWKNKQYRVPIYQCLFFNAETHSLHTFLVIGNEISENLLDKISISKEKIFMWDLNEQIMSITQKTESICELMFGNKQIIQKLSRTFIFLTIILNSNMYEIIDVCIDSNAVLYMPDLRPMIIRCVGNYSKISSELLSDSDCTQATKKMRFDYHVTNFCFSLNVNGKKVLFSSTESSESILEKLLEFFTIQTYKLAEEQFLMVTPKNFFTVLFDEDMCLLLLQTVVSFLYDNLFRNKLVVKQVHDYIGPDLWPQGHERAVYFVGFPNMWFLSIYDLDNKIPCIKNICNRILLYCGLPDSLGPDGCQSVPSTQCVDEFEDLPNLGALQYLKYNSLVVTMETVENSENVYYFFGEQDLFIVKLVDIIQSLLELYVPKSFLPDFSDAYIKSEILLKFISRLHKKSNNIFCKIVKKITEFLRCFLNACRLMDLNWMFIRNMHIVYFIGPKKDPSVVLPLLKTSVESCWKKILNSSRTPVVNINYIPGYNFLHSSCSFLTSGDINSEDSHWTITASKCLYNCLGASQITVDFKNIYTNFQQMVSVFLSHRYENKYWIEYFEPNNYFLETHEGLLDCNRYTAVWTTENKLIRQSVGYPLTDKIDFIHYIQVVIEIFKKWLLTKYSQQEYAETVRLGSKIISDHLHLFNVN
What is the function of this protein?
Component of the helicase/primase complex.  Unwinds the DNA at the replication forks and generates single-stranded DNA for both leading and lagging strand synthesis.  The primase synthesizes short RNA primers on the lagging strand that the polymerase presumably elongates using dNTPs.  The primase-associated factor has no known catalytic activity in the complex and may serve to facilitate the formation of the replisome by directly interacting with the origin-binding protein and the polymerase.
What are the official names of this protein?
DNA helicase/primase complex-associated protein, HEPA, Primase-associated factor.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae HEPA family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: RIR1A_MYCS2
Sequence: MPPTVTAAEPVTTTGHVLPGEADYHALNAMLNLYDADGKIQFEKDREAAKQYFLQHVNQNTVFFHSQDEKLDYLIENEYYEREVLDQYSRDFIKSLLDRAYAKKFRFPTFLGAFKYYTSYTLKTFDGKRYLERFEDRVVMVALTLAAGDTELAEKLVDEIIDGRFQPATPTFLNSGKKQRGEPVSCFLLRIEDNMESIGRSINSALQLSKRGGGVALLLSNIREHGAPIKNIENQSSGVIPIMKLLEDSFSYANQLGARQGAGAVYLHAHHPDIYRFLDTKRENADEKIRIKTLSLGVVIPDITFELAKKNEDMYLFSPYDVERVYGVPFADVSVTEKYYEMVDDARIRKTKINAREFFQTLAELQFESGYPYIMFEDTVNRSNPIAGKITHSNLCSEILQVSTPSEFNDDLSYAKVGKDISCNLGSLNIAKAMDSPDFAQTIEVAIRALTAVSDQTHITSVPSIEQGNNDSHAIGLGQMNLHGYLARERIYYGSEEGIDFTNIYFYTVLFHALRASNKIAIERGTHFKGFEKSKYASGEFFDKYTDQVWEPKTDKVRRLFADADIHIPTQDDWKQLKESVQKHGIYNQNLQAVPPTGSISYINHSTSSIHPVASKIEIRKEGKIGRVYYPAPYMTNDNLDYYQDAYEIGYEKIIDTYAAATQHVDQGLSLTLFFKDTATTRDVNKAQIYAWRKGIKTLYYIRLRQMALEGTEVEGCVSCML
What is the function of this protein?
Provides the precursors necessary for DNA synthesis.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).
What are the official names of this protein?
Ribonucleoside-diphosphate reductase subunit alpha 1, Ribonucleotide reductase R1 subunit 1.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase large chain family.
Protein: RS14Z_OCEIH
Sequence: MAKKSMIAKQKRPQKFKVQEYTRCERCGRPHSVIRKFKLCRICFRELAYKGQIPGVKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: LPLA_SALNS
Sequence: MTTLRLLISDSYDPWFNLAVEECIFRQMPATQRVLFLWRNADTVVIGRAQNPWKECNTRRMEEDNVRLARRSSGGGAVFHDLGNTCFTFMAGKPEYDKTISTHIVLAALNSLGVMADASGRNDLVVKTPDGDRKVSGSAYRETKDRGFHHGTLLLNADLSRLAIYLNPDKKKLAAKGITSVRSRVANLTELLPGITHKQVCQAVTEAFFVHYGERVDAEVISPDKTPDLPNFAETFARQSSWEWNFGQAPAFSHLLDERFTWGGVELHFDVEKGVITRAQVFTDSLNPAPLEALAERLQGCLYRADKLQETCEALLVDFPEQEKELRELSAWIAEAVR
What is the function of this protein?
Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.
What are the official names of this protein?
Lipoate-protein ligase A, Lipoate--protein ligase.
What is the protein family that this protein belongs to?
Belongs to the LplA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_SHIBS
Sequence: MQVILLDKVANLGSLGDQVNVKAGYARNFLVPQGKAVPATKKNIEFFEARRAELEAKLAEVLAAANARAEKINALETVTIASKAGDEGKLFGSIGTRDIADAVTAAGVEVAKSEVRLPNGVLRTTGEHEVSFQVHSEVFAKVIVNVVAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.