PharMolix/UniProtQA huggingface dataset:
Protein: MASZ_GEOKA
Sequence: MGEYVQKGNIQVAKVLYDFVNEELLPNSGLDQDKFWSDFGALISDLTPRNKELLARRDEIQEKLNEWHKAHRGRFDFNEYKAFLTDIGYLEPEVEDFEITTDNVDDEIAVQAGPQLVVPLTNARYALNAANARWGSLYDALYGTDAISEEDGAERGSSYNPVRGAKVIAYGRQFLDEAVPLAQYSHKDAVQYAIVDGQLVVTTEGGATTGLKEPEKFVGFQGDPQHPTAVLLKNNGLHIEIQIDREHAVGKTDQAGVKDIVLEAAVTTIMDGEDSVAAVDAEDKVLVYRNLFGLVKGDLTATFEKNGKIMTRSLNPDRVYKTPDGGELVLPGRSLMFVRNVGHLMTNNAILHANGEEVHEGIMDAVITSLIMKHSLIGNTRYLNSRKGSIYIVKPKMHGSAEVAFANELFDRVEDMLGLERNTIKIGVMDEERRTSLNLKNCIYQVRDRIIFINTGFLDRTGDEIHTSMEAGPMLRKNEMKSSTWLQAYEKSNVAVGLAAGFRGRAQIGKGMWAMPDLMAEMLKQKGAQLKAGANTAWVPSPTAATLHALHYHQVNVSAVQSELANDRNDYRDDMLQIPVVDHPQWTAEEIQEELDNNCQSILGYVVRWIDQGIGCSKVPDIHNVGLMEDRATLRISSQILANWLHHGICTKEQVLETLKRMAKVVDEQNAGDPNYRPMAPNYDDSVAFQAACDLIFRGYEQPNGYTEPILHRRRQEAKAKFAAIQQ
What is the function of this protein?
Involved in the glycolate utilization.  Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
What are the official names of this protein?
Malate synthase G.
What is the protein family that this protein belongs to?
Belongs to the malate synthase family. GlcB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_PHOV8
Sequence: MAKHDLHLTRNIGIMAHIDAGKTTTSERILFYTGLTHKIGEVHDGAATMDWMEQEQERGITITSAATTTRWKYAGNTYKINLIDTPGHVDFTAEVERSLRVLDGAVAAYCAVGGVEPQSETVWRQADKYNVPRIGYVNKMDRSGADFFEVVRQMKDVLGANACPVVIPIGAEESFKGVVDLIKMKAILWHDETMGADYSVEEIPANLVDEANEWREKMLEKVAEFDDALMEKFFDDPSTITEEEILRALRAGTLKMDIVPMFCGSSFKNKGVQTLLDYVCAFLPSPLDTPAIVGTNPTTGAEEDRKPSEDEKTSALAFKIATDPYVGRLTFFRVYSGKVEAGSYIYNTRSGKKERVSRLFQMHSNKQNPVEVIGAGDIGAGVGFKDIRTGDTLCDEDAPIVLESMEFPDPVIGIAVEPKTQKDLDKLSNGLAKLAEEDPTFTVKTDEQSGQTIISGMGELHLDIIIDRLKREFKVECNQGKPQVNYKEAITKTVELREVYKKQSGGRGKFADIIVAIGPVDEDFTQGGLQFIDEVKGGNVPKEFIPSVQKGFQTAMKNGVLAGYPLDSLKVVLKDGSFHPVDSDQLSFEICAIQAYKNACAKAGPVLTEPIMKLEVVTPEENMGDVIGDLNKRRGQVEGMESSRSGARIVKAKVPLAEMFGYVTALRTITSGRATSSMTYDHHAQVSSSIAKAVLEEVKGRVDLV
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYODA_XENLA
Sequence: MELLPPPLRDMEVTEGSLCAFPTPDDFYDDPCFNTSDMSFFEDLDPRLVHVTLLKPEEPHHNEDEHVRAPSGHHQAGRCLLWACKACKRKTTNADRRKAATMRERRRLSKVNEAFETLKRYTSTNPNQRLPKVEILRNAIRYIESLQALLHDQDEAFYPVLEHYSGDSDASSPRSNCSDGMMDYNSPPCGSRRRNSYDSSFYSDSPNDSRLGKSSVISSLDCLSSIVERISTQSPSCPVPTAVDSGSEGSPCSPLQGETLSERVITIPSPSNTCTQLSQDPSSTIYHVL
What is the function of this protein?
May act as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation.
What are the official names of this protein?
Myoblast determination protein 1 homolog A, Myogenic factor 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: CSTR2_ORYSI
Sequence: MEYRRVKDQESYDVVSQKDIESPGERSLSSTSATSSLSTAGASKGNNSWKLKSIVTLALTLLTSSQAILIVWSKRAGKYEYSVTTANFSVEALKCLLSLIALYRTWNSQGVTEDNRLSTSFDEVSVYPIPAILYMVKNLLQYYIFAYVDAPAYQILKNLNIISTGVLYRIILKKKLSEIQWAAFILLCAGCTTAQLNPSSDHVLQTPIQGWVMAIVMALLSGFAGVYTEAIIKKRPSRNINVQNFWLYIFGMLFNLVAICVQDFDAVMNKGFFHGYSFITVLMILNHALSGIAVSMVMKYADNIVKVYSTSVAMLLTAVVSVFLFGFHLSLAFFLGSTVVSVSVYLHSVGKPQPQK
What is the function of this protein?
Sugar transporter involved in the transport of CMP-sialic acid from the cytoplasm into the Golgi.  May transport important nucleotide sugars such as CMP-Kdo (2-keto-3-deoxy-D-manno-octulosonic acid) in physiological conditions.
What are the official names of this protein?
CMP-sialic acid transporter 2, CMP-SA-Tr 2, CMP-Sia-Tr 2, CMP-sialic acid transporter-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the nucleotide-sugar transporter family. CMP-Sialate:CMP antiporter (TC 2.A.7.12) subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: YCF4_STIHE
Sequence: MNSENLIRRYVITGSRRLSNYWWASVVFLGAIGFLFTGLSSYFGQNLLPFLQVQNITFFPQGLVMSFYGILGLLLSIYLWLTIIWNVGGGFNEFNKKAGAIRIFRWGFPGKTRCIDISYSLKEVEAIKVDFKQGVNPQRTLYLRVKGKREIPLSQIGQPLTVEEVEKQAAELAKFLQVSVEGL
What is the function of this protein?
Seems to be required for the assembly of the photosystem I complex.
What are the official names of this protein?
Photosystem I assembly protein Ycf4.
What is the protein family that this protein belongs to?
Belongs to the Ycf4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RIMO_ECO8A
Sequence: MSKVTPQPKIGFVSLGCPKNLVDSERILTELRTEGYDVVPSYDDADMVIVNTCGFIDSAVQESLEAIGEALNENGKVIVTGCLGAKEDQIREVHPKVLEITGPHSYEQVLEHVHHYVPKPKHNPFLSLVPEQGVKLTPRHYAYLKISEGCNHRCTFCIIPSMRGDLVSRPIGEVLSEAKRLVDAGVKEILVISQDTSAYGVDVKHRTGFHNGEPVKTSMVSLCEQLSKLGIWTRLHYVYPYPHVDDVIPLMAEGKILPYLDIPLQHASPRILKLMKRPGSVDRQLARIKQWREICPELTLRSTFIVGFPGETEEDFQMLLDFLKEARLDRVGCFKYSPVEGADANALPDQVPEEVKEERWNRFMQLQQQISAERLQEKVGREILVIIDEVDEEGAIGRSMADAPEIDGAVYLNGETNVKPGDILRVKVEHADEYDLWGSRV
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM3_THEVB
Sequence: MIATSSRPVRIGSRKSQLALVQTEWVQAQLQTHHRDRAFEVVTMTTQGDNILDVALAKIGDKGLFTKELELSMLRGETDLAVHSLKDLPTQLPDGLVLAAITEREDPADALVLGAKWTGHTIDTLPEGTVIGTSSLRRLAQLRHYYPHLTFKDVRGNLNTRLAKLDAGEYDALILAVAGLRRLGFGDRISQVLPATVSLYAVGQGALGIECRAEDADILALVKTLEHPETTARCLAERAFLRQLEGGCQVPIGVHTVIENGQLTLTGLVASLDGQRLVKDSLTGDVATAEELGTRLALKLREQGASEILEEIFATVRPER
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: OSK4_ORYSI
Sequence: MEGNARGGGHSEALKNYNLGRTLGIGSFGKVKIAEHKLTGHRVAIKILNRRQMRNMEMEEKAKREIKILRLFIHPHIIRLYEVIYTPTDIYVVMEYCKFGELFDYIVEKGRLQEDEARRIFQQIISGVEYCHRNMVVHRDLKPENLLLDSKYNVKLADFGLSNVMHDGHFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSHLSALARDLIPRMLVVDPMKRITIREIREHQWFQIRLPRYLAVPPPDTAQQAKMIDEDTLQDVVNLGYEKDHVCESLRNRLQNEATVAYYLLLDNRFRATSGYLGADYQESLERNLNRFASSESASSNTRHYLPGSSDPHASGLRPHYPVERKWALGLQSRAQPREIMIEVLKALEDLNVCWKKNGQYNMKCRWSVGYPQATDMLDVNHSFVDDSIIMDNGDVNGRLPAVIKFEIQLYKSRDEKYLLDMQRVTGPQLLFLDFCAAFLTKLRVL
What is the function of this protein?
Suppressor of flowering in long days (LD) via the that up-regulation of HD1 and the down-regulation of EHD1.  Can phosphorylate HD1 in the presence of HDR1.
What are the official names of this protein?
Serine/threonine protein kinase OSK4, OsK4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNH_ECO7I
Sequence: MLKQVEIFTDGSCLGNPGPGGYGAILRYRGREKTFSAGYTRTTNNRMELMAAIVALEALKEHCEVILSTDSQYVRQGITQWIHNWKKRGWKTADKKPVKNVDLWQRLDAALGQHQIKWEWVKGHAGHPENERCDELARAAAMNPTLEDTGYQVEV
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPG_HALHL
Sequence: MSADTQSETLEFQAEVQQLLSLMIHSVYSNREVFLRELISNASDAIDKLRFEALQQESLYEDDPELKIRVEADPEARTVTVIDNGIGMSREDVIENLGTIAHSGTRRFLEQLTGDQHKDAQLIGQFGVGFYSAFVVADRVEVYTRKAGAAAAEGVRWSSDGQGAYTVDTVERAERGTAVVLHLPEAQQEFCDDMRLRQIIRKYSDHISVPIEMPVRNADQGDDADSEAEAPQWEIVNRASALWMRPKSEISEEDYQELYKHVAHDFDDPLTWIHNHVEGRQSYVSLLYIPKRPPFDLYEQKPAHGVKLYVRRVFITEDTEHLLPRYLRFVRGVIDSDDLPLNISREMLQHNPMISSLRSASVKRILDRLECMAKNEPEDYATFWQAFGRVFKEGIAEDPGNRERIARLLRFSSTHEEKETPDVSLDDYVARMKDGQEKIYYVTAESFNAARNSPHLEIFRRHGIEVLLLPDPVDEWLVAHLHEYDGKQLASVAKGELDLEALGEEDDKQARQEKEQAYEDLCKRLGETLGERVSEVRVSHRLTDSPACLVVGEYDFGMGMQRLLQAAGHQLPAGQPALEVNPDHSVIERLATESGQRFEDWALTLYEQSLLAEGGQLEDPAAYVRRVNNLLAG
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARPIN_BOVIN
Sequence: MSRIYQDSALRNKAVRSARLPGAWDPAAHQRGDGVLLEGELLDVSRHSILDAHGRKERYYVLYIRPSRIHRRKFDPKGNEIEPNFSATRKVNTGFLMSSYKVEAKGDSDRLTPEALKGLVNKPELLALTESLTPAETVAFWMPESEMEAMELELGAGVRLKTRGDGPFLDSLAKLEAGTVTKCNFAGDGKTGASWTDNIMAQKSSEGAASETREQGDGAADEEWDD
What is the function of this protein?
Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competitive with nucleation promoting factors.  Participates in an incoherent feedforward loop at the lamellipodium tip where it inhibits the ARP2/2 complex in response to Rac signaling and where Rac also stimulates actin polymerization through the WAVE complex.  Involved in steering cell migration by controlling its directional persistence (By similarity).
What are the official names of this protein?
Arpin.
What is the protein family that this protein belongs to?
Belongs to the Arpin family.
What are the subcellular locations of this protein?
Cell projection, lamellipodium. Note=Colocalized with the WAVE complex at lamelliupodium tip.
Protein: DTD_MYCBO
Sequence: MRVLVQRVSSAAVRVDGRVVGAIRPDGQGLVAFVGVTHGDDLDKARRLAEKLWNLRVLADEKSASDMHAPILVISQFTLYADTAKGRRPSWNAAAPGAVAQPLIAAFAAALRQLGAHVEAGVFGAHMQVELVNDGPVTVMLEG
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOF_BURPS
Sequence: MNPLATLEQGLADIDAQGLRRCRRVADTACGAHMTVDGRAIIGFASNDYLGLAAHPRLVEAFAEGARRYGSGSGGSHLLGGHSRAHATLEDELAAFSGGFSDAPRALYFSTGYMANLAALTALAGRGATIFSDALNHASLIDGARLSRANVQIYPHGDADALDARLRACDAPTKLIVSDTVFSMDGDVAPLARLVALAETHGAWLVVDDAHGFGVLGPQGRGALAAHGLRSPNLVYVGTLGKAAGVAGAFVVAHETVIEWLVQRARSYIFTTAAPPSVACAVSASLAVIASDEGDARRAHLGALIKRTRAILRATHWQPVDSHTAVQPLVIGSNEATLAAMAALDAQGLWVPAIRPPTVPAGTSRLRISLSAAHSFDDLARLEAALVTPIGAAA
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: ILVD_ECOSE
Sequence: MPKYRSATTTHGRNMAGARALWRATGMTDADFGKPIIAVVNSFTQFVPGHVHLRDLGKLVAEQIEAAGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDQIIKLDLVDAMIQGADPKVSDSQSDQVERSACPTCGSCSGMFTANSMNCLTEALGLSQPGNGSLLATHADRKQLFLNAGKRIVELTKRYYEQNDESALPRNIASKAAFENAMTLDIAMGGSTNTVLHLLAAAQEAEIDFTMSDIDKLSRKVPQLCKVAPSTQKYHMEDVHRAGGVIGILGELDRAGLLNRDVKNVLGLTLPQTLEQYDVMLTQDDAVKNMFRAGPAGIRTTQAFSQDCRWDSLDDDRANGCIRSLEHAYSKDGGLAVLYGNFAENGCIVKTAGVDDSILKFTGPAKVYESQDDAVEAILGGKVVAGDVVVIRYEGPKGGPGMQEMLYPTSFLKSMGLGKACALITDGRFSGGTSGLSIGHVSPEAASGGSIGLIEDGDLIAIDIPNRGIQLQVSDAELAARREAQEARGDKAWTPKNRERQVSFALRAYASLATSADKGAVRDKSKLGG
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: TRMB_STAHJ
Sequence: MRVRYKPWAEDYLKEHPNLVDMDGAHAGKMSEWFDKEQPIYIEIGSGMGQFITTLASKFPEINFVSMEREKSVMYKVLDKVKELNLTNLKMICNDAIELNEYFNDGEISRIYLNFSDPWPKKRHAKRRLTYHTFLALYQQILKEDGEIHFKTDNRGLFAFSLESMSQYGMYFTKLNLNLHDEDDEDNILTEYEKKFSEKGSRIYRMEAKFHKSI
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: DAPA_PSE14
Sequence: MIAGSMVALVTPMDAQGRLDWDSLSKLVDFHLQEGTNAIVAVGTTGESATLDVSEHIEVIRRVVAQVAGRIPVIAGTGANSTREAVELTTNAKTAGADACLLVTPYYNKPTQEGLFQHFSHIANAVDIPQILYNVPGRTACDMLPETVARLSTVKNIIGIKEATGNLQRAKDILASVSSDFLVYSGDDATAVELMLLGGKGNISVTANVAPRLMSDLCAAAMRGDAETARAIHEKLMPLNNTLFIESNPIPVKWALHEMGKMPAGIRLPLTWLSEACHEPLRQALRQSGVLV
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_PROM9
Sequence: MTISDKIRIYELSRDLNLENKDILDAAQKLSISVKSHSSSISVEEAKKIKNLINKKNSDKQILSINKPSNKKDNYKQNKEDKSPVISSVKGKPLKDNSNKKQLLNKPLNKPESLKVIPNQLKNPNKPNIYNSSQSQANLTNQNTKSKPSEHFNKDKKTFRNNTIPPIKTPAKPPIQLIAKPKNINNNLKSNESSKNIPNSGDKRELSLKPDQNRNKPKPKNSNNRRNTPELVGAPIRRDDPNKQNNKQNITFKQTVSNRPGTPNRPGTPNRPGMPNRPGLRNKPTDQGRPGSFNRQANPNRAGAPNRPGMPNRPGLRNKPTDQGRPGSFNRQANPNRAGAPNRPGMPNRPGSRFNSQKSTGIRKPVSPNELLQLQKTNKSEKDTLAKTNNQKQNIESPKQKAKAPASRPNAVPSSKKPPHRPFSNSSKKPGRKDWDDSAKLEALRNKNPQKQRQKVHIIGENDDSLTSETSGYSGEKISILSASLARPKKEKSEESKSHKSTKQFKKKKKETTRQRQKRRAMELKAAKEAKQVRPEMIIVPEDNLTVQELADKLSLESSEIIKSLFFKGITATVTQSLDLATIETVAEEFGVPVLQDDIQEAAEKTVDMIESDDFDSLIKRPPVITVMGHVDHGKTSLLDSIRESRVASGEAGGITQHIGAYQVEFKHESKKKKLTFLDTPGHEAFTAMRARGTKVTDVAVLVVAADDGCRPQTLEAISHARAAKVPIVVAINKIDKEGASPERVKQELSEKDLIAEDWGGDTVMVPVSAIKKQNIDKLLEMILLVSEVEDLQANPDRSAKGTVIEAHLDKAKGPVATLLVQNGTLKSGDVLAAGSVLGKIRAMVDEHGNRIKEAGPSFPVEALGFSEVPTAGDEFEVYPDEKTARAIVGDRATDARATKLAQQMASRRVTLSSLSTQANDGELKELNLILKADVQGSVEAILGSLEQLPKNEVQVRVLLSAPGEITETDIDLAAASGSVIIGFNTSLASGAKRAADANDVDIREYEVIYKLLEDIQLAMEGLLEPDLVEESLGKAEVRATFAVGKGAIAGCYIQTGKLQRNCSLRVIRSDKVIFEGNLDSLKRSKDDVKEVNTGFECGVGCDKFSSWTEGDIIEAFKFVTKKRTLTQ
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDUS3_HUMAN
Sequence: MAAAAVARLWWRGILGASALTRGTGRPSVLLLPVRRESAGADTRPTVRPRNDVAHKQLSAFGEYVAEILPKYVQQVQVSCFNELEVCIHPDGVIPVLTFLRDHTNAQFKSLVDLTAVDVPTRQNRFEIVYNLLSLRFNSRIRVKTYTDELTPIESAVSVFKAANWYEREIWDMFGVFFANHPDLRRILTDYGFEGHPFRKDFPLSGYVELRYDDEVKRVVAEPVELAQEFRKFDLNSPWEAFPVYRQPPESLKLEAGDKKPDAK
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor (PubMed:14729820, PubMed:30140060).  Essential for the catalytic activity and assembly of complex I (PubMed:14729820, PubMed:24028823, PubMed:30140060).
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial, Complex I-30kD, CI-30kD, NADH-ubiquinone oxidoreductase 30 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: TCAF1_BOVIN
Sequence: MATPSAAFEALMNGVTSWNVPEDAVPCELLLIGEASFPVMVNDMGQVLIAASSYGRGRLVVVSHEDYLVEAQLTPFLLNAVGWLCSSPGAPVGVHPSLAPLAKILEGSGVEAKVEPEVKDSLGVYCIDAYNETMTEKLVKFMKRGGGLLIGGQAWDWANQGDDERVLFTFPGNLVTSVAGVYFTDNKGDTSFFKVSKKMPKIPVLVSCEDDLSEDRDELLHGISELDITNSDCFPSQLLVHGALAFPLGLDSYHGCVIAAARYGRGRVVVTGHKVLFTVGKLGPFLLNAVRWLDAGRRGKIVVQTELRTLSGLLAVGGIDTSIEPNLTSDASVYCFEPVSDVGVKELQEFVAEGGGLFVGAQAWWWAFKNPGVSPLARFPGNLLLNPFGISITSQSLNPGPFRTPKAGIRTYHFRSTLAEFQVIMGRKRGNVEKGWLAKLGPDGAAFLQIPAEEIPAYMSVHRLLRKLLSRYRLPVATRENPVINDCCRGAMLSLATGLAHSGSDLSLLVPEIEDMYSSPYLRPSESPITVEVNCNNPGTRYCWMSTGLYIPGRQIIEVSLPEAAASADLKIQIGCHTDDLTRASKLFRGPLVINRCCLDKPTKSITCLWGGLLYIIVPQSSKLGTVPVTIKGAVRAPYYKLGETTQEEWKRQIQENPGPWGELATDNIILTVPTANLRTLENPEPLLRLWDEVMQAVARLGAEPFPLRLPQRIVADVQISVGWMHAGYPIMCHLESVQELINEKLIRTKGLWGPVHELGRNQQRQEWEFPPHTTEATCNLWCVYVHETVLGIPRGRANIALWPPVREKRVRIYLGKGPNVKNWNAWTALETYLQLQEAFGWEPFIRLFTEYRNQTNLPTDNVDKMNLWVKMFSHQVQKNLAPFFEAWAWPIQKEVATSLAYLPEWEENIMKLYLLTQMPH
What is the function of this protein?
Positively regulates the plasma membrane cation channel TRPM8 activity.  Involved in the recruitment of TRPM8 to the cell surface.  Promotes prostate cancer cell migration inhibition in a TRPM8-dependent manner.
What are the official names of this protein?
TRPM8 channel-associated factor 1, TRP channel-associated factor 1.
What is the protein family that this protein belongs to?
Belongs to the TCAF family.
What are the subcellular locations of this protein?
Cell membrane. Note=Colocalizes with TRPM8 on the plasma membrane.
Protein: NUOC_MOOTA
Sequence: MDNFIQELQRLFPDLEVREGVDVPALVVPADQLLALMTELKEKRGFNFLADLTAVDYPEDERIEMVYHLLSVPGMAEIRVKVNLDRQHPEVPSLTALWPAANVQEREAFDLMGVKFPGHPDLKRILCPDDFVGHPLRKDFRLQTEGGE
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GLMU_PAEAT
Sequence: MSPETIGPAAVIVLAAGAGTRMKSRTPKILHEIGGRSMVGHALLAARAINPLKLALVVRHERDRVAEHVTASDPEALIVDQDDVPGTGRAVEVALKALDAEAELTGTVVVTYGDVPLLTGELLGELVATHEAEGNAVTVLTAVLDDATGYGRILRAENGTVTGIREHKDASEAERTIREVNSGIYAFDAAVLRTALEKVTTDNAQGEMYLTDVLGLARDAGGRVAAVVTEDRWQVEGANDRIQLSALAAEHNRRIIESWMRAGVTVVDPATTWIDSTVTLDEDVRLLPNTQLHGSTTVARDAVVGPDTTLTDVNVGEGAKVIRTHGSGSTIGAKASVGPFTYLRPGTVLGETGKIGAFYETKNVTIGRGSKLSHLGYAGDAEIGEDTNIGCGNITANYDGEKKHRTVIGSGVRTGSNTVFVAPVTVGDGAYSGAGAVIRKDVPAGALALSLAAQRNAEGWVAANRPGTASAKLAEAAQELASTSSQFQATIEEGKQA
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRC_CUPTR
Sequence: MTQKLTITRPDDWHLHLRDGAALAAVLPDTARQFARAIVMPNLKPPVTTVAQAQAYRARILAALPAGMQFEPLMTLYLTDNTGPEEIAAARASGFVHGVKLYPAGATTNSDAGVTDIRRCYPALEAMQRAGLPLLVHGEVTDPAIDIFDREAVFIERVMTPLRRDMPELKVVFEHITTKDAAQYVRDASGPVGATITAHHLLYNRNAIFTGGIRPHYYCLPVLKRETHREALVAAATSGSERFFLGTDSAPHARGLKEHACGCAGCYTALHAMELYAEAFDAAGALDKLEAFASFNGPAFYGLPRNTGTLTLEREDWELPAELPYGDTTLVPLRGGETLRWKAR
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: ODPT_ASCSU
Sequence: SNIFKGPTVGSSVVAMSARLASTEATFQAKPFKLHKLDSGPDVNMHVTKEDALRYYTQMQTIRRMETAAGNLYKEKKVRGFCHLYSGQEACAVGMKAAMEPGDAAITAYRCHGWTYLSGSPVAKVLCELTGRITGNVYGKGGSMHMYGENFYGGNGIVGAQQPLGTGIAFAMKYKKQKNVCITLFGDGATNQGQLYESMNMAKLWELPVLYVCENNGYGMGTSAARSSASTDYYTRGDYVPGFWVDGMDVLAVRQAIRWGKEWCNAGKGPLMIEMATYRYGGHSMSDPGTSYRTREEIQEVRKTRDPITGFKDKIVTAGLVTEDELKEVDKEIRKEVDAAVKQAHTDKEAPVEMLLTDIYYNTPAQYVRCTTEDVLQQYVTSEEAFKALSK
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
What are the official names of this protein?
Pyruvate dehydrogenase E1 component subunit alpha type II, mitochondrial, PDHA2, PDHE1-A.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: COMT1_POPKI
Sequence: MGSTGETQMTPTQVSDEEAHLFAMQLASASVLPMILKTAIELDLLEIMAKAGPGAFLSTSEIASHLPTKNPDAPVMLDRILRLLASYSILTCSLKDLPDGKVERLYGLAPVCKFLTKNEDGVSVSPLCLMNQDKVLMESWYYLKDAILEGGIPFNKAYGMTAFEYHGTDPRFNKVFNKGMSDHSTITMKKILETYKGFEGLTSLVDVGGGTGAVVNTIVSKYPSIKGINFDLPHVIEDAPSYPGVEHVGGDMFVSVPNADAVFMKWICHDWSDAHCLKFLKNCYDALPENGKVILVECILPVAPDTSLATKGVVHVDVIMLAHNPGGKERTEKEFEGLANGAGFQGFEVMCCAFNTHVIEFRKKA
What is the function of this protein?
Catalyzes the conversion of caffeic acid to ferulic acid and of 5-hydroxyferulic acid to sinapic acid.  The resulting products may subsequently be converted to the corresponding alcohols that are incorporated into lignins.
What are the official names of this protein?
Caffeic acid 3-O-methyltransferase 1, CAOMT-1, COMT-1, S-adenosysl-L-methionine:caffeic acid 3-O-methyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. COMT subfamily.