PharMolix/UniProtQA huggingface dataset:
Protein: UPPP_METMP
Sequence: MEELILGIVQGLTEFLPISSSGHLAIFTALFNSTPDVGYFAFLHLATFLAVLIFVKAEVFEIITGITKKETEYINLASKLVLSTIPAVIVGLCFGDFIESVFSSTLLIGVFLSITGILMLLSDNLNKNLKTIKSIPYWDALIIGVFQAFSVLPGISRSGTTLFAALFLGMNKEDAVKYSFLMSLPVTFGAGILELQKITFSSEQLFGFVISFLTGLLGLYLVKKMVIGGKLKIFGYYCFLASFFVIMFL
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).
What are the official names of this protein?
Undecaprenyl-diphosphatase, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: H3A09_CYRHA
Sequence: MKASMFLALAGLALLFVVCYASESEEKEFPIELLSKIFAVDVFKGEERGCKGFGDSCTPGKNECCPNYACSSKHKWCKVYLGK
What is the function of this protein?
Selective antagonist of neuronal tetrodotoxin (TTX)-sensitive voltage-gated sodium channels (IC(50)=1270 nM on Nav1. 1/SCN1A, 270 nM on Nav1. 2/SCN2A, 491 nM on Nav1. 3/SCN3A and 232 nM on Nav1. 7/SCN9A).  This toxin suppress Nav1. 7 current amplitude without significantly altering the activation, inactivation, and repriming kinetics.  Short extreme depolarizations partially activate the toxin-bound channel, indicating voltage-dependent inhibition of this toxin.  This toxin increases the deactivation of the Nav1. 7 current after extreme depolarizations.  The toxin-Nav1. 7 complex is gradually dissociated upon prolonged strong depolarizations in a voltage-dependent manner, and the unbound toxin rebinds to Nav1. 7 after a long repolarization.  Moreover, analysis of chimeric channels showed that the DIIS3-S4 linker is critical for toxin binding to Nav1. 7.  These data are consistent with this toxin interacting with Nav1. 7 site 4 and trapping the domain II voltage sensor in the closed state.
What are the official names of this protein?
Hainantoxin-III 9, HnTx-III, Hainantoxin-3.9, Mu-theraphotoxin-Hhn2a, Mu-TRTX-Hhn2a, Peptide F7-18.76.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 15 (Hntx-3) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: AKH2_AGRIP
Sequence: MCRIFIVLLVVAALAIIIEGQLTFSSGWGNGKRSISSEQINDDCNPEEAIFQIYKLIVSEGERIRACQRDGKM
What is the function of this protein?
This hormone, released from cells in the corpora cardiaca, causes release of diglycerides from the fat body and stimulation of muscles to use these diglycerides as an energy source during energy-demanding processes.
What are the official names of this protein?
Adipokinetic prohormone type 2.
What is the protein family that this protein belongs to?
Belongs to the AKH/HRTH/RPCH family.
What are the subcellular locations of this protein?
Secreted.
Protein: ERG11_BRANA
Sequence: MDLAFPHVCLWTLLAFVLTWTVFYVNNRRKKVAKLPDAATEVRRDGDADVIIVGAGVGGSALAYALAKDGRRVHVIERDMREPVRMMGEFMQPGGRLLLSKLGLEDCLEGIDEQIATGLAVYKDGQKALVSFPEDNDFPYEPTGRAFYNGRFVQRLRQKASSLPTVQLEEGTVKSLIEEKGVIKGVTYKNSAGEETTAFAPLTVVCDGCYSNLRRSVNDNNAEVISYQVGYVSKNCQLEDPEKLKLIMSKPSFTMLYQISSTDVRCVMEIFPGNIPSISNGEMAVYLKNTMAPQVPPELRKIFLKGIDEGAQIKAMPTKRMEATLSEKQGVIVLGDAFNMRHPAIASGMMVVLSDILILRRLLQPLRNLSDANKVSEVIKSFYVIRKPMSATVNTLGNAFSQVLIASTDEAKEAMRQGCFDYLSSGGFRTSGMMALLGGMNPRPLSLIFHLCGITLSSIGQLLSPFPSPLGIWHSLRLFGAEGVSQMLSPAYAAAYRKSYMTATAL
What is the function of this protein?
Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
What are the official names of this protein?
Squalene monooxygenase 1,1, Squalene epoxidase 1,1, SE 1,1.
What is the protein family that this protein belongs to?
Belongs to the squalene monooxygenase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: A1H_LOXSM
Sequence: AGNRRPIWIMGHMVNAIGQIDEFVNLGANSIETDVSFDDNANPEYTYHGIPCDCGRNCKKYENFNDFLKGLRSATTPGNSKYQEKLVLVVFDLKTGSLYDNQANDAGKKLAKNLLQHYWNNGNNGGRAYIVLSIPDLNHYPLIKGFKDQLTKDGHPELMDKVGHDFSGNDDIGDVGKAYKKAGITGHIWQSDGITNCLPRGLSRVNAAVANRDSANGFINKVYYWTVDKRSTTRDALDAGVDGIMTNYPDVITDVLNEAAYKKKFRVATYDDNPWVTFKK
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LsSicTox-alphaIA1, LsD1, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D 1, SMD 1, SMase D 1, Sphingomyelinase D 1.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RHLB_VIBA3
Sequence: MKKTHITEQKFADLDLLPQVIEGLEKKGFDYCTPIQALALPVLLTGQDIAGQAQTGTGKTLAFLTATFNHLLKTPEHEGRKPNQPRAIIMAPTRELAIQIYNDADSLVASTGIKAALAYGGESYDKQLGKIEEGADILIGTTGRIIDFYKQKVFNLNHIQAVVLDEADRMFDLGFIKDIRFLFRRMPEPKDRLNMLFSATLSYRVQELAFEHMHNPEHVVVEPERKTGHRIQEELFYPSNEHKMALLQTLIEEEWPDRAIIFANTKHKCESVWGHLAADGHRVGLLTGDVPQKKREKILEQFTKGDVDLLVATDVAARGLHIPQVTHVFNFDLPDDCEDYVHRIGRTGRAGESGHSISFACEDYAINLPPIEEYIEHAIPMSDYDASALLEDLPAPMRLRTRNPQQRRSNNNGPRNGNRKPNQNRRPRQPRHNKEA
What is the function of this protein?
DEAD-box RNA helicase involved in RNA degradation.  Has RNA-dependent ATPase activity and unwinds double-stranded RNA.
What are the official names of this protein?
ATP-dependent RNA helicase RhlB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. RhlB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOLB_SHESA
Sequence: MKILAKWLALAVLLCTMPAKAALDIVITEGVDAARPIAVMPFQWQGAGAPPQAIADVVMSDLIRSGTFKPLDELGLPQRGIGALAQFDASAWANVGAEAVVVGSVKPYGTDQFLVSFDLIDLVKAQNQALKGPTSATEFLMDSRQTVISAAQFRQYGHRISDIVYEKLTGIRGAFLTRISYVVVNHTQKAAYSLMIADYDGYNEQMLLRSPEPLMSPSWSPDGRRLAYVSFENKKAEIFVQDLYTQVRTKVSSFPGINGAPTFSPDGKSLAVTLSKDGQPEIYVIDIATKAAKRITNHYSIDTEPSWYPDGKSLLFTSERGGRPQLYRVDLNSGKVTRETFEGEWNLGGSITPDGRSMIFVNRTNGKFNIARMDLSTRFMQVLTSTRLDESPSVAPNGTMVIYGTTYQGKQVLAAVSTDGRFKARLPVGQGEVKSPSWSPFL
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: LEUO_ECOLI
Sequence: MPEVQTDHPETAELSKPQLRMVDLNLLTVFDAVMQEQNITRAAHVLGMSQPAVSNAVARLKVMFNDELFVRYGRGIQPTARAFQLFGSVRQALQLVQNELPGSGFEPASSERVFHLCVCSPLDSILTSQIYNHIEQIAPNIHVMFKSSLNQNTEHQLRYQETEFVISYEDFHRPEFTSVPLFKDEMVLVASKNHPTIKGPLLKHDVYNEQHAAVSLDRFASFSQPWYDTVDKQASIAYQGMAMMSVLSVVSQTHLVAIAPRWLAEEFAESLELQVLPLPLKQNSRTCYLSWHEAAGRDKGHQWMEEQLVSICKR
What is the function of this protein?
A global transcription factor.  Activates transcription of the 9 following operons; yjjQ-bglJ, yjjP, acrEF, ybdO, yjcRQP, casABCDE12, rhsD-ybbC, fepE and gltF, in most cases it probably interferes with silencing by H-NS and activates transcription.  Represses transcription of the 3 following operons; uxaCA, sdaCB and btsT.  H-NS repression of the bgl operon, leading to the ability to metabolize some beta-glucosides.  It also directly activates the bgl operon.  Activation is H-NS and BglJ-RcsB independent.
What are the official names of this protein?
HTH-type transcriptional regulator LeuO.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: PTG3C_STAAW
Sequence: MRKKLFGQLQRIGKALMLPVAILPAAGLLLAIGTAMQGESLQHYLPFIQNGGVQTVAKLMTGAGGIIFDNLPMIFALGVAIGLAGGDGVAAIAAFVGYIIMNKTMGDFLQVTPKNIGDPASGYASILGIPTLQTGVFGGIIIGALAAWCYNKFYNINLPSYLGFFAGKRFVPIMMATTSFILAFPMALIWPTIQSGLNAFSTGLLDSNTGVAVFLFGFIKRLLIPFGLHHIFHAPFWFEFGSWKNAAGEIIHGDQRIFIEQIREGAHLTAGKFMQGEFPVMMFGLPAAALAIYHTAKPENKKVVAGLMGSAALTSFLTGITEPLEFSFLFVAPLLFFIHAVLDGLSFLTLYLLDLHLGYTFSGGFIDYFLLGILPNKTQWWLVIPVGLVYAVIYYFVFRFLIVKLKYKTPGREDKQSQAATASATELPYAVLEAMGGKANIKHLDACITRLRVEVNDKSKVDVPGLKDLGASGVLEVGNNMQAIFGPKSDQIKHEMQQIMNGQVVENPTTMEDDKDETVVVAEDKSATSELSHIVHAPLTGEVTPLSEVPDQVFSEKMMGDGIAIKPSQGEVRAPFNGKVQMIFPTKHAIGLVSDSGLELLIHIGLDTVKLNGEGFTLHVEEGQEVKQGDLLINFDLDYIRNHAKSDITPIIVTQGNITNLDFKQGEHGNISFGDQLFEAK
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  This system is involved in glucose transport.
What are the official names of this protein?
PTS system glucose-specific EIICBA component, EIICBA-Glc, EII-Glc, EIICBA-Glc 1.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MYG_KATPE
Sequence: MADLDAVLKCWGAVEADFNTVGGLVLARLFKDHPETQKLFPKFAGITGDIAGNAAVAAHGATVLKKLGELLKAKGNHAAIIKPLANSHAKQHKIPINNFKLITEALAHVLHEKAGLDAAGQTALRNVMGIVIADLEANYKELGFTG
What is the function of this protein?
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
What are the official names of this protein?
Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: CYPH_NEUCR
Sequence: MFGPRHFSVLKTTGSLVSSTFSSSLKPTATFSCARAFSQTSSIMSKVFFDLEWEGPVLGPNNKPTSEIKAQSGRINFTLYDDVVPKTARNFKELCTGQNGFGYKGSSFHRIIPEFMLQGGDFTRGNGTGGKSIYGEKFADENFAKKHVRPGLLSMANAGPNTNGSQFFVTTVPTSWLDGRHVVFGEVADDESMKVVKALEATGSSSGAIRYSKKPTIVDCGAL
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase, mitochondrial, PPIase, Cyclophilin, CPH, Cyclosporin A-binding protein, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family.
What are the subcellular locations of this protein?
Mitochondrion. Cytoplasm.
Protein: COAD_PHOPR
Sequence: MTTRVIYPGTFDPITNGHLDLIERAAAMFDHVVVGIAASPSKKPLFDLPERVALTQAITKHLPNVEIVGFSGLLVDFAKESNANILVRGLRAVSDFEYEFQLANMNRRLMPELETVFLTPSEENSFISSTIVKEVALHKGDVSQFVDLRITGALNAKLHTK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y157_MYCPN
Sequence: MKPPKKPVNPPFGKLTDSKAGVVKATSSQETKKVADTKPKNKGGLFSFFKKDKTEKPAKAAKPKDAFKSAIAELNPKANPKTVKADVAPAKIPHSDKGTVTPVELKPQTEAPLPPGVKQPDPKKDKPKGGLFGFFKKDKNKDVKKEPAKPATPVKTEPTSPKVEPTKVKPPGGVPTKPVVEKPVSAQPTVPLQPEPTFPVKAAPLPPGVKAEPESKKRFGLFKAFQKDDAKQPKQKLNLQDQQDRFIDDPTAKKHFSAFNQKVGNLLKDKKTRNRDWKIVGWIHGLILLFFIPLLAIMNKFVTLPAQSYPAVSLQVSINNALWGIAIFVIANIALPFITMFVLFLTGVRDVHASRPVHYFIWVLMLLNLTFLVISCCLLAAAYANLDLYNIWRNLQALDPNN
What are the official names of this protein?
Uncharacterized protein MG144 homolog.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HIS2_BRUO2
Sequence: MSQFTLADLERIVAERASVTDGTSYTASLVAKGQPKAAQKLGEEAVETVIAAVSGDRAGVVSESADLLYHLAVVWNIAGVALEDVLQELQRRTAQTGLAEKASRPKG
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_BURMS
Sequence: MLQPKRRKYRKEQKGRNTGIATRGNAVSFGEFGLKAVGRGRLTARQIEAARRAMTRHIKRGGRIWIRIFPDKPISQKPAEVRMGNGKGNPEYYVAEIQPGKMLYEMDGVSEELAREAFRLAAAKLPLKTTFIVRQLGA
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: FA53B_MOUSE
Sequence: MVMILRRSLINQGADSGAHRTFIPELHTPKMSQGPTLLSCGIMENDRWRDLDRKCPLQIDQPSASIWECLPEKCQDGSLWHQEAVTACAVTSLIKDLNINDHNGNPSAPPSKRQCRSLSFSDEMSSCRTSWRPLGSKVWTPVEKRRCYSGGSVQRYSNGVSPMQRSSSFSLPARANGLSSPCHQSSLHHRFGGQPCQGAPGSAPCGQAGDSWSPDPHPVGGGRLDLQRSLSCSHEQFSFPEYCPPSANSTPASTPELARRSSGLARSRSQPCVLNDKKIGVKRRRPDEVQEQRPSLDLAKMAQNCQTFSSLSCLNMGVDDHSSQSPFALVSSTRSWTALLSASSPGGRTPAGTPVPEPVPHSFDDQFTCQEDLSCDESDGCSLDEDCCRKGDPATSWRDRGACTNSLCSLDGELDIEQIENN
What is the function of this protein?
Acts as a regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) nuclear localization.
What are the official names of this protein?
Protein FAM53B.
What is the protein family that this protein belongs to?
Belongs to the FAM53 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MDTH_ECOUT
Sequence: MSRVSQARNLGKYFLLIDNMLVVLGFFVVFPLISIRFVDQMGWAAVMVGIALGLRQFIQQGLGIFGGAIADRFGAKPMIVTGMLMRAAGFATMGIAHEPWLLWFSCLLSGLGGTLFDPPRSALVVKLIRPQQRGRFFSLLMMQDSAGAVIGALLGSWLLQYDFRLVCATGAVLFVLCAAFNAWLLPAWKLSTVRTPVREGMTRVMRDKRFVTYVLTLAGYYMLAVQVMLMLPIMVNDVAGAPSAVKWMYAIEACLSLTLLYPIARWSEKHFRLEHRLMAGLLIMSLSMMPVGMVSGLQQLFTLICLFYIGSIIAEPARETLSASLADARARGSYMGFSRLGLAIGGAIGYIGGGWLFDLGKSAHQPELPWMMLGIIGIFTFLALGWQFSQKRAARRLLERDA
What is the function of this protein?
Confers resistance to norfloxacin and enoxacin.
What are the official names of this protein?
Multidrug resistance protein MdtH.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CSD_MYCTO
Sequence: MTASVNSLDLAAIRADFPILKRIMRGGNPLAYLDSGATSQRPLQVLDAEREFLTASNGAVHRGAHQLMEEATDAYEQGRADIALFVGADTDELVFTKNATEALNLVSYVLGDSRFERAVGPGDVIVTTELEHHANLIPWQELARRTGATLRWYGVTDDGRIDLDSLYLDDRVKVVAFTHHSNVTGVLTPVSELVSRAHQSGALTVLDACQSVPHQPVDLHELGVDFAAFSGHKMLGPNGIGVLYGRRELLAQMPPFLTGGSMIETVTMEGATYAPAPQRFEAGTPMTSQVVGLAAAARYLGAIGMAAVEAHERELVAAAIEGLSGIDGVRILGPTSMRDRGSPVAFVVEGVHAHDVGQVLDDGGVAVRVGHHCALPLHRRFGLAATARASFAVYNTADEVDRLVAGVRRSRHFFGRA
What is the function of this protein?
Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
What are the official names of this protein?
Probable cysteine desulfurase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
Protein: NREC_STAA3
Sequence: MKIVIADDHAVVRTGFSMILNYQNDMEVVATAADGVEAYQKVMEYKPDVLLMDLSMPPGESGLIATSKIADSFPETKILILTMFDDEEYLFHVLRNGAKGYILKNAPDEQLLLAIRTVYKGETYVDMKLTTSLVNEFVSNSNQDTANTTDPFKILSKRELEILPLIAKGYGNKEIAEKLFVSVKTVEAHKTHIMTKLGLKSKPELVEYALKKKLLEF
What is the function of this protein?
Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen.  Phosphorylated NreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT, and activates their expression (By similarity).
What are the official names of this protein?
Oxygen regulatory protein NreC, Nitrogen regulation protein C.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROK_CHRSD
Sequence: MQGLPTIILVGPMGAGKSTIGRLLAAELQREFFDSDHEIEARCGANIAWIFDVEGEAGFRDRETAMLRELASLDAVVLATGGGAVMREDNRQALRERGTVVYLATSVEQQIRRTARDRNRPLLRQGNPEQVLRDLFAKRDPLYRATADLVVRTDRRGPRAVVNEIIRRTKRLSDPLDLKA
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPG_TRIEI
Sequence: MQTLANPSKTPINQAVFDTTIHRRKTRSVKVGDITIGGGHPVVVQSMINEDTLDIERSVAAIRRLHEIGCEIVRVTVPSIAHAKSLGEIKQKLAETYKPVPLVADVHHNGMKIALEVAKQVDKVRINPGLYVFEKPQAERNEYTQAEFEEIGDKIRQTLKPLVVSLRDQNKAMRIGVNHGSLSERMLFTYGDTPEGMVESALEFIKICESLKYYNLVISLKASRVPVMLAAYRLMVKRMDELGMPYPLHLGVTEAGDGDYGRVKSTAGIGTLLAEGIGDTIRVSLTEAPEKEIPVCYSILQALGLRKTMVEYVACPSCGRTLFNLENVLHEVREATKHLTGLDIAVMGCIVNGPGEMADADYGYVGKQSGYISLYRGREEIKKVHESQGVEELINLIKADGRWVEP
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: RNFG_PHOLL
Sequence: MLETMRRHGITLAIFAALTTGLTAVVNSLTKSTIAEQAALQHKSLLDQVIPPALYDNDIQNECYLVNANALGNNLPHRLYLARKNGHPVAAALESTAPDGYSGAIQLLVGADFSGKVLGVRVTEHHETPGLGDKIETRISNWINVFSGKTITSNHDQHWAVKKDGGEFDQFTGATITPRAVVNSVKRTALYLQTIPEHLSSLESCGEKS
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit G, Rnf electron transport complex subunit G.
What is the protein family that this protein belongs to?
Belongs to the RnfG family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PPNP_SHIF8
Sequence: MLQSNEYFSGKVKSIGFSSSSTGRASVGVMVEGEYTFSTAEPEEMTVISGALNVLLPDATDWQVYEAGSVFNVPGHSEFHLQVAEPTSYLCRYL
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: IBP3_PIG
Sequence: MQRARPALWAAALIALALLRGPPAARAGSGAAGTGPVVRCEPCDARALAQCAPPPAAPPCAELVREPGCGCCLTCALREGQACGVYTERCGAGLRCQPPPGEPRPLQALLDGRGICANASAAGRLRAYLLPAPPAPGNGSESEEDRSVDSMENQALPSTHRVPDSKLHSVHTKMDVIKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNMLSPRGIHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGFDVKGKGDVHCYSMESK
What is the function of this protein?
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture.  They alter the interaction of IGFs with their cell surface receptors.  Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R.  Promotes testicular germ cell apoptosis (By similarity).
What are the official names of this protein?
Insulin-like growth factor-binding protein 3, IBP-3, IGF-binding protein 3, IGFBP-3.
What are the subcellular locations of this protein?
Secreted.
Protein: MK67I_XENLA
Sequence: MAEELVQSEKLLSLDPKLQEDFQQKVHDIRRKRKANALTPGVIYIGHIPKSLIEPQLQEYFNQFGTVTRLRLSRSKKTGNSKGYAYVEYECDEVAKIVADTMNNYLFCERLLKCEFVTPEKVHPRLFIGCNTRFRKPTKPAVTRYNSKRNKEEVKKMTQRMISKEYKLRKRLAEKGIDYDFPGFAAHREMRKELTCDANTSVSSQDPTPVCTPTVLERRKSVRLEQIEDEEEDDDEVVLKLPQRDDEVVVKLPQKVSSAAKRQKISKLGKKTNIKELK
What are the official names of this protein?
MKI67 FHA domain-interacting nucleolar phosphoprotein-like.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: EXD1_BOMMO
Sequence: MDNLYTKGELLQVHTKNYDVFEGRFYSMAQDKTKISLYDVKEIPHGDANDGVLHYYDSEIREVVKLQESTEKKVLKISQTKYEEILKISKKYIFINQVDKSFHEAVDDLNQQDFIAVSGDGANMGRKCKMPFLVLSTDHQIYIFDIQVMQYHAFESGLKKILEGDSPKKIAHDCRKLSDCLYHKHNVKLKSVFDTQVGDLIITKNKKVTLPNKVKSLGECLTNYLGLQQNTIDEKLDIVQSTERPLSVKIKDSLARNIAFLHHLSEVINEEMQLPFYRGVECYIENIRSSDDFKAWELCGKLNQIPKEFRNAIDY
What is the function of this protein?
RNA-binding component of the PET complex, a multiprotein complex required for the processing of piRNAs during spermatogenesis.  The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposable elements, preventing their mobilization, which is essential for the germline integrity.  The PET complex is required during the secondary piRNAs metabolic process for the PIWIL2 slicing-triggered loading of PIWIL4 piRNAs.  In the PET complex, EXD1 probably acts as an RNA adapter.  EXD1 is an inactive exonuclease.
What are the official names of this protein?
piRNA biogenesis protein EXD1, Exonuclease 3'-5' domain-containing protein 1, Exonuclease 3'-5' domain-like-containing protein 1, Inactive exonuclease EXD1, BmExd1.
What is the protein family that this protein belongs to?
Belongs to the EXD1 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Component of the meiotic nuage, also named P granule, a germ-cell- specific organelle required to repress transposon activity during meiosis.
Protein: TRPB2_PYRAB
Sequence: MKVVLPDGRIPRRWYNILPDLPEPLDPPLDPETEEPIDIEKLKRIFAEELVKQEISRERYIEIPGELRKLYSKIGRPTPLFRATNLEKLLGTPARIYFKYEGATVTGSHKINTALAQAYYAKKQGIERLVTETGAGQWGTALSLAGALLGLKVRVYMARASYQQKPYRKTLMRIYGAEVFPSPSENTEVGKRFLKEDPNHPGSLGIAISEAIEDVLKDEKARYSLGSVLNHVLMHQTVIGLEAKEQMEEFEEPDVIIGCVGGGSNFAGLAYPFVKDVLDGKSEYEFIAVEPKAAPTMTRGVYTYDYGDSAGLTPKLKMHTLGHRYYVPPIHAGGLRYHGLAPTLSVLINHGIVKPIAYHQTEVFEAAVLFAKAEGIVPAPESAHAVKAVIDKALEARREGKEMVILFNLSGHGLLDLKGYEDYLDGKLEDYEPRDLPVKS
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain 2.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: PVK2_BLAGI
Sequence: GSSGLISMPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-2, BlaGi-PVK-2, PVK-2.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1510_STAA2
Sequence: MKNYSFYQFVMTVRGRHDDKGRLAEEIFDDLAFPKHDDDFNILSDYIETHGDFTLPMSVFDDLYEEYTEWLKF
What are the official names of this protein?
UPF0346 protein SaurJH1_1510.
What is the protein family that this protein belongs to?
Belongs to the UPF0346 family.