PharMolix/UniProtQA huggingface dataset:
Protein: IF3_CHLMU
Sequence: MALNLKINRQIRAPRVRVIGSSGEQLGILSIKEALDLAREADLDLVEVASNSEPPVCKIMDYGKYRYDVTKKEKDSKKAQHQVRVKEVKLKPNIDDNDFLTKVKQARAFIEKGNKVKVSCMFRGRELAYPEHGHKVVQRMCQGLEDVGFVESEPKLNGRSLICVIAPGTLKTKKKQEKVHAQDEKQ
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRB_CUPPJ
Sequence: MSNLAEVAPALDEDKIVTFPGSPFQLYQPFPPAGDQPEAIRQLVEGIEDGLSFQTLLGVTGSGKTYTMANVIARMGRPAIVFAPNKTLAAQLYSEFREFFPRNAVEYFVSYYDYYQPEAYVPQRDLFIEKDSSINEHIEQMRLSATKSLLERRDTIIVATVSAIYGIGNPNEYHQMILTLRTGDKISQRDVIARLIAMQYTRNETDFQRGTFRVRGDTIDIFPAEHAEMAVRLEMFDDEVESLQFFDPLTGRVRQKIPRFTVYPSSHYVTPRETVLRAIEDIKAELRDRLEFFHKENRLVEVQRLEQRTRFDLEMLSELGFCKGIENYSRHLSGAKPGEPPPTLVDYLPSDALMFLDESHVLIGQLNGMYNGDRARKTTLVEYGFRLPSALDNRPLKFEEFERKMRQVMFVSATPAQFEKEHAGQVVEQVVRPTGLVDPIIIVRPATTQVDDLLSEINLRVEAGERVLVTTLTKRMAEQLTEFLSENGVKVRYLHSDIDTVERVEIIRDLRLGTFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRAERSLIQTIGRAARNVNGTAILYADRITDSMRKAIDETERRRAKQMAFNEANGITPRGVIKRIKDIIDGVYDAGEVKAELLAAQERARYEDMSEKQVSKEIKRLEKLMMDHAKNLEFEKAAQVRDQLAKLKAQLFGASGEEAPMPPV
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_LISMH
Sequence: MKANDIRDLSTTEIQDQEKALKEELFNLRFQLATGQLENTARIREVRKAIARMKTIVRERELA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: DPOL_ADE04
Sequence: MALVQTHGSRGLHPEASDPGRQPSRRRSRQSSPGAVPEPARARRRRAPATTASGSRAAPTARRASSPPLLTMEAKPLPPAKKKRGTVVTPQGHGTLQAIDVATNGAVEIKYHLDLPRALEKLLQVNRAPPLPTDLTPQRLRTLDSSGLRALVLALRPVRAEVWTCLPRGLVSMTTIEAEEGQADHHDVVQHQMQAPRLHFPLKFLVKGTQVQLVQHVHPVQRCEHCGRLYKHKHECSARRRHFYFHHINSHSSNWWQEIQFFPIGSHPRTERLFLTYDVETYTWMGSFGKQLVPFMLVMKLSGDDRLVELALDLALQLKWDRWHGDPRTFYCVTPEKMAVGQQFRQYRDRLQTALAVDLWTSFLRANPHLADWALEQHGLSDPDELTYEELKKLPHVKGRPRFVELYIVGHNINGFDEIVLAAQVINNRAEVPQPFRITRNFMPRAGKILFNDVTFALPNPAYKKRTDFQLWEQGGCDDIDFKHQFLKVMVRDTFALTHTSLRKAAQAYALPVEKGCCAYKAVNQFYMLGSYRADQDGFPLEEYWKDREEFLLNRELWKQKGQLKYDIIQETLDYCALDVLVTAELVAKLQDSYAHFIRDSVGLPHAHFNIFQRPTISSNSHAIFRQIVYRAEKPSRANLGAGLLAPSHELYDYVRATIRGGRCYPTYIGILDEPLYVYDICGMYASALTHPMPWGTPLSPYERALAVREWQASLDDLGTCISYFDPDLLPGIFTIDADPPDELMLDPLPPFCSRKGGRLCWTNEPLRGEVATSVDLITLHNRGWQVRIVPDELTTVFPEWKCVAREYVQLNIAAKERADKEKNQTMRSIAKLLSNALYGSFATKLDNKKIVFSDQMDEGLLKGISAGTVNIKSSSFLETDNLSAEVMPAFEREYLPQHVALLDSDPEDSEDEQRPAPFYTPPAGTPGHVAYTYKPITFLDVDEGDMCLHTLEKVDPLVDNDRYPSHVASFVLAWTRAFVSEWSGFLYDEDRGVPLEDRPIKSVYGDTDSLFVTQRGHELMETRGKKRIKKNGGKLVFDPNQPDLTWLVECETVCAHCGADAYAPESVFLAPKLYALKSLLCPACGQTSKGNVRAKGHAAEALNYELMVNCYLADAQGADRERFSTSRMSLKRTLASAQPGAHPFTVTETTLTRTLRPWKDRTLAALDAHRLAPYSRSRPNPRNEEVCWIEMP
What is the function of this protein?
Eukaryotic-type DNA polymerase involved in viral genomic replication.  DNA synthesis is protein primed, and acts in a strand displacement replication.  Assembles in complex with viral pTP, DBP, host NFIA and host POU2F1/OCT1 on viral origin of replication.  The polymerase covalently transfers dCMP onto pTP, thereby initiating complementary strand synthesis.
What are the official names of this protein?
DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: GLPX_CORGL
Sequence: MNLKNPETPDRNLAMELVRVTEAAALASGRWVGRGMKNEGDGAAVDAMRQLINSVTMKGVVVIGEGEKDEAPMLYNGEEVGTGFGPEVDIAVDPVDGTTLMAEGRPNAISILAAAERGTMYDPSSVFYMKKIAVGPEAAGKIDIEAPVAHNINAVAKSKGINPSDVTVVVLDRPRHIELIADIRRAGAKVRLISDGDVAGAVAAAQDSNSVDIMMGTGGTPEGIITACAMKCMGGEIQGILAPMNDFERQKAHDAGLVLDQVLHTNDLVSSDNCYFVATGVTNGDMLRGVSYRANGATTRSLVMRAKSGTIRHIESVHQLSKLQEYSVVDYTTAT
What is the function of this protein?
Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate.  Is essential for growth on gluconeogenic carbon sources.  Also displays a low activity toward glucose 6-phosphate, and fructose 6-phosphate, glycerol 3-phosphate, ribulose 1,5-bisphosphate and myo-inositol-monophosphate are not significant substrates.
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 2, FBPase class 2, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 2.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HMC1A_METSH
Sequence: AETRNFALRDKKGNEIGVFTGKQPRQAALKAANRGHKDIRLRERGTKKVHIFAGERVKVKKPKGAPAWMPNEIWKPKVKKIGVEKLDEI
What is the function of this protein?
Protects DNA against thermal denaturation and modulates transcription.
What are the official names of this protein?
Chromosomal protein MC1a.
Protein: LFTR_FLAPJ
Sequence: MHFLTQELSFPNTNESTRDGLLAIGGDLSTQRLLLAYENGIFPWFEEGEPIMWWSPRQRMVLFFDALVVSHSMRNVINKNIFKVTFNKAFREVIQNCQSVKREGQHGTWITNEMIESYCKLHELGKAISVEIWQNDTLVGGLYGVDMFPVFCGESMFSKVSNASKMAFISLADYLKTNHYNLLDCQIYNDHLNSLGCREIPRDEFLKFLKK
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINE_METEP
Sequence: MSVLTFLKPRGSGSVARERLQLILAHERVENGRPDLIITLREEILNVIAKHVTVERDKVQIKLERGEGVSTLGVDIEFPVDAVIKPKAKTKRAIA
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: TRMB_ANOGA
Sequence: MEEAIDDHVKLPQKRFYRQRAHSNPIADHSFDYPLLPELSNWNELYPNIGNRQVVFADIGCGYGGFLVTLGETFPDKLAIGMEIRVKVSDYVMDRIKALRQRHKGKYENIACIRTNAMKYLPNYFRKHQLEKLFFLYPDPHFKKAKHKWRIINPTLLSEYAYVLRPGGKIYTVTDVRELHEWMCKHIEEHPCFKRLPDTEAQEDILAPKLLDSSEEGQKVTRMSGEKFMAIFTRL
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GPDA_RHOP5
Sequence: MTSISSIAVLGGGAWGTALAQTAARAGRAVTLWEHDATNAQQLQSARESLYLPGVTLEPAIKVTRDLAEAARADAILLVVPAQVLRQVVTSLAPLIGAQTPLIACAKGIEHGTHKFMTEIIAEAAPNALPAILSGPSFAADVARGLPTAVTIAAADAAVAQALAQAMNCGSFRPYHSTDVRGVELGGATKNVMAIAAGIVEGRKLGASALAAMTTRGFVELVRFGTAYGARIETMHGLSGLGDLTMCCSTPQSRNFSFGMALGRGESVATAAHGKLAEGAFTAPVLLEMARAKHVEMPISEAVAAILEGQTTVDAAIGALLTRPLKAE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEK4_MOUSE
Sequence: MPQAAYCYMRVVGRGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQLKHPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPESQVVEWFVQIAMALQYLHEKHILHRDLKTQNVFLTRTNIIKVGDLGIARVLENHGDMASTLIGTPYYMSPELFSNKPYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPPMPKVYSTELAELIRTMLSRRPEERPSVRSILRQPYIKHHISLFLEATKAKTSKNNVKNCDSRAKPVAAVVSRKEESNTDVIHYQPRSSEGSALHVMGEDKCLSQEKPVDIGPLRSPASLEGHTGKQDMNNTGESCATISRINIDILPAERRDSANAGVVQESQPQHVDAADEVDSQCSISQEKERLQGNTKSSDQPGNLLPRRSSDGGDGEGSELVKPLYPSNKDQKPDQDQVTGIIENQDSIHPRSQPHSSMSEPSLSRQRRQKKREQTAHSGTKSQFQELPPRLLPSYPGIGKVDIIATQQNDGNQGGPVAGCVNSSRTSSTASAKDRPLSARERRRLKQSQEEMLPSGPAVQRTPSAVEPLKPQEEDQPIPAQRFSSDCSITQMNHTLPREKEKRLMHGLSEDELSSSTSSTDKSDGDSREGKSHTNEMKDLVQLMTQTLRLEAKESCEDLQVLNPGSEFRLHRKYRDTLVLHGKVAEEVEPHCTELPTGIIPGSEKIRRIVEVLRADVIQGLGIQLLEQVFDLLGEEDELEREARLQEHMGDKYTTYCVKARQLKFFEENVSF
What is the function of this protein?
Required for normal entry into proliferative arrest after a limited number of cell divisions, also called replicative senescence.  Required for normal cell cycle arrest in response to double-stranded DNA damage (By similarity).  Protein kinase that seems to act exclusively upon threonine residues.
What are the official names of this protein?
Serine/threonine-protein kinase Nek4, Never in mitosis A-related kinase 4, NimA-related protein kinase 4, Serine/threonine-protein kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, cilium.
Protein: MKT1L_TRYB2
Sequence: MRKAGANRNNERQGRNLGQQGPQMSPPGPSMMYPHHHQHQHHHQHQHQHQHQHQHPHQHPHQHHHHHPHHNGVYGNAYDNIRQPQMPPHSFGQGVSGSPWNSPPQQTPMYNQGYNQMSPGTGGGYGDMGGMYRDVHGGQYPSSPSHMGGGANIPYGRNPAMHNGLPAGAPLPGGYGALPHQGAHTPMGFGRGGQPLMEHMQPSGMYGAPMMRHDGYPDTRVSPPAQVGYGAGAPVGPPPPPPMPAGPPYGGVLPGAGVGPGGPMNASRPPAGIGGGGGGGGNAGYLEMRARGMGPQMPASNASRPPRIGTPDPGMMPPNRMNQSPMMGQGLPPQVGNFMPLPGVSPSPHAMIPTTPSMGDTFPGDDANMSGSTEALYDFLHDRGLVSVDNISKFFPEGYGKDDPALKVAVDGNFCLTSLRDELRKRDSLWFLHSTLPEELLMLVQQHVEWMRNMKLEPIWVFNGLSVSGDVETFLTTEAELRARDAVWSKLEDGEIPDEVEIQEAFDQPLGEDVQMAVARYLKEELGVMAVTAPFLNWAQMVAFHKEGIADLLMGPPEMLLLPYDEMKVIVQIDVSNSSVNYLDRDRVLRALFPNHVTETNTRVAGDRLMDLGLITATHAALSSARVTLNLSMQEVYEELSTPTPKFRSIKDFINAHACSQETGKKAGLSIKHSKGRGYLRYSAVFSTKSRDTPLVYLVRVLDPDLTNADMPTNLAGVLGHLVPLSLFYMQFSGLLSVRIMTAITQSYLRDECPVSDTKDYHTTLGLLMTMRSQVIGQILKRIAHPPPIKRTECLSWVRWFQPILAPMDRPRDLIDLDEWEISDSDQLKKLDEDCLADYSIASVLSVTADASRPAVEESNRPAGRVPIRYNSKRETFLAILLKSFDFLGYFSHSTAPNDAVDGMEMECCGMDGHDRGGSVPAAYHEKDLSSMKRSEASDINFMADEGLKDYPSVYFPIYLRATIKANPLDVQASFVLLTELVRVRIINSNPCRYINPANQQVEISMDDQDTNSDSRVLLASRIACLVKLPYRRASENLPFVWAPVYSRHLCAFTVMVRAMCRCLRELVEVITSTVFLSGNSSCSLQDFAEFASILPFGDVPSTIGGLLLHYVLVFPSDYQANLTSREERIEYLQGKFRDIPDLADHLHLVMSFTLQALYLINAYMLNDKETIVAKDQLTGTIVEDTIEMMWQKWRDHIDDNPPGDIHNLYPPRHQEPIPH
What is the function of this protein?
Involved in post-transcriptional regulation of gene expression.
What are the official names of this protein?
Post-transcriptional regulator MKT1L, Inactive endonuclease MKT1L.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VIF_SIVG1
Sequence: MEREKQWIVRVVWRVSERQISRWRGIVTYKIRNKQLPWEYRHHWQVQWQFWTYSQFIIPLSKDDYIEVNIYHNLTPERGWLSSHGVGLSYYHQKGYKTEVDPGTADRMIHLYYFNCFTDRAIQQAIRGEKYTWCTFKEGHKGQVQSLQLLALVAYTNGIRKRSKRTFTRMAGNLGSRQGAMGRMATRHAQGSKRRSQKALWNEHANPSMELLCRGGKET
What is the function of this protein?
Counteracts the innate antiviral activity of APOBEC3G.  Forms a complex with host APOBEC3G thus preventing the entry of this lethally hypermutating enzyme into progeny virions.  Functions as an adapter molecule, recruiting APOBEC3G to the ubiquitin-proteasome machinery.  Targets APOBEC3G for degradation through the assembly with elongin BC complex, CUL5 and RBX1.  Binds viral RNA and affects the stability of viral nucleoprotein core.  May play a role in viral morphology (By similarity).
What are the official names of this protein?
Virion infectivity factor, Vif, Q protein, SOR protein.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group Vif protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Virion. Note=Seems to colocalize with intermediate filament vimentin. A fraction is associated with the cytoplasmic side of cellular membranes, presumably via the interaction with Pr55Gag precursor (By similarity).
Protein: CC69B_XENLA
Sequence: MGSKTSKMCCPQLRKKKRQKAHKEGPSSQELNDLNAKSQGPNELLQKIKEYEQEIRNILQKHQEEKTALADAHKADVEARTLVLQAQAQKDRDAETVKLLSEQAATMKAEMEEMFAELQKSYEQEKSSLTEIHQQLTDALQESVDELNSQLASFREKMKRVEESILSQDYQRHIQDYGSPGQFWEKELQSLHFVIEMKSELIREQDKRLQRHKSTMERSLELEERSRTLQQENEALKVQTQKQGAITVRLSEELLSIQTTLEKQTHRCEQLEREKEQNLYRAVIGDITQQFSLQELPVMVL
What is the function of this protein?
May act as a scaffold to regulate the recruitment and assembly of spindle midzone components.
What are the official names of this protein?
Coiled-coil domain-containing protein 69-B.
What is the protein family that this protein belongs to?
Belongs to the CCDC69 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, spindle. Midbody. Note=During early anaphase, localizes along overlapping interpolar microtubules between the separating chromosomes. During late anaphase, localizes to the center of spindle midzone. Concentrated at the midbody during telophase.
Protein: GE_CHV1
Sequence: MRPPVRASLGLLVAWAIGACVCAAAIETTWKHASAGDEVRLFALPAARPGAPPAKVVWELDPMAACGSLRPSWVSLRPPGQVLDTVVDAECVSEPVLLAAWYERRDGGSEVPAPFWGPDGAPPQRGNVTNGTLVLREARVGDSGMHVLSVFHPPNATAARHVVFLKVAPRRPEPAGGTPPPRDDEEGGTEEPATPAPPPHPHPIAEVAHVRGVTVSLRTQTAILFAPGDTVHTDVSVMPIAHDDDPYVMEVVWVRFDVPEECGEMRIYEPCLYHPQLPECRSPADAPCAASVWTERLAVRRYGPCSRGVPPPRCPSDAAMESRAGLGWYGHTVNLQLRDASEASGGLYVCVVYVNGHVHAWGHVVISTASRYRNAVVERSPPRYRPPPVEPTPSAQPTGPRPAAPRAARLVGVLGAAVGLAVAGLSVWACVTCRRARAWRAVKRRDLMAPTYIRLADDELYGDLSSYGDSDDSEYDSDSDRLPGTDPAPKRGSGFQILSGAKADPWSAGARQHGHLITFRADDTSRYRDPSSPDPPHRR
What is the function of this protein?
In epithelial cells, the heterodimer gE/gI is required for the cell-to-cell spread of the virus, by sorting nascent virions to cell junctions.  Once the virus reaches the cell junctions, virus particles can spread to adjacent cells extremely rapidly through interactions with cellular receptors that accumulate at these junctions.  Implicated in basolateral spread in polarized cells.  In neuronal cells, gE/gI is essential for the anterograde spread of the infection throughout the host nervous system.  Together with US9, the heterodimer gE/gI is involved in the sorting and transport of viral structural components toward axon tips (By similarity).
What are the official names of this protein?
Envelope glycoprotein E, gE.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae glycoprotein E family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host cell junction. Host Golgi apparatus membrane; Single-pass membrane protein. Host endosome membrane; Single-pass membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN), maybe through an interaction with PACS-1 sorting protein. The heterodimer gE/gI then redistributes to cell junctions to promote cell-cell spread later in the infection (By similarity).
Protein: PSBF_PROM9
Sequence: MTNSQAPMQAAEVRVYPIFTVRWLAVHALAIPSVFFLGSIAAMQFVAR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: BTUD_ECOK1
Sequence: MSIVMQLQDVAESTRLGPLSGEVRAGEILHLVGPNGAGKSTLLARMAGMTSGKGSIQFAGQPLEAWSATKLALHRAYLSQQQTPPFAMPVWHYLTLHQHDKTRTELLNDVAGALALDDKLGRSTNQLSGGEWQRVRLAAVVLQITPQANPAGQLLLLDEPMNSLDVAQQSALDKILSALCQQGLAIVMSSHDLNHTLRHAHRAWLLKGGKMLASGRREEVLTPANLAQAYGMNFRRLDIEGHRMLISTI
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Vitamin B12 import ATP-binding protein BtuD, Vitamin B12-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Vitamin B12 importer (TC 3.A.1.13.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NOC_BACLD
Sequence: MKHSFSRLFGLGDKEEEAEIAEHDTNKEEIQEIPVGDIIPNRFQPRTIFSEEKIKELAATIHTHGIIQPIVVRKTEREGQYELIAGERRWRAVQTLDWEKVPAIIKDFSDTETASVALIENLQREELSSIEEAHAYARLLELHDLTQEALAQRLGKGQSTIANKLRLLKLPEEVQEAILKKEISERHARALIPLKQPDLQVKLLHEVIEKSLNVKQTEDRVVKMLEQDKRKPKPKRKAYSRDARIAMNTIRQSLSMVEDSGVKLNTEEEEFEEYIQFTIRIPK
What is the function of this protein?
Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle.  It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage.
What are the official names of this protein?
Nucleoid occlusion protein, Noc.
What is the protein family that this protein belongs to?
Belongs to the ParB family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RL3_KOCRD
Sequence: MTTTFERQVKGLLGTKLGMTQVWDENGKFVPVTVVKADSNVVTQLRNTDKDGYNAVQIGFGAIDPRKVTKPLAGHFAAAGVTPRRHVVELRTSDAAEYELGQELSVELFEAGAKVDVVGTTKGKGTAGVMKRHGFSGVGASHGAHKNHRKPGSIGGASYPARVFKGMRMAGRMGNARHTTMNLTVHAVDAENSLLLIKGALPGPKGSVVLVRSTVKGA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: RL362_NEIMF
Sequence: MQVLSSLKTAKQRHRDCQIVRRRGKVYVICKSNPRFKARQR
What are the official names of this protein?
50S ribosomal protein L36 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: RL14_ALCBS
Sequence: MIQTESMLEVADNSGARRVQCIKVLGGSHRRYAGIGDIIKVTVKEAIPRGRVKKGDVMTAVVVRTRKGVRRPDGSLIRFDENAAVLLNNNKAPVGTRIFGPVTRELRTEQFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: THI41_PHYPA
Sequence: MSISAAGVATGLGANVELKSNVGSSSSSVAGVRLFTSRKAQLRRCAAPATSASLYSDANYDLNNYKFAPIKESIVAREMTRRYMTDMITHADTDVVVVGAGSAGLSCAYELSKNPNVKVAIVEQSVSPGGGAWLGGQLFSAMIVRKPAHRFLDEIEVPYEEMENYVVIKHAALFTSTIMSKLLARPNVKLFNAVAAEDLIIRGDRVSGVVTNWALVAQNHNTQSCMDPNVMEAKVVVSSCGHDGPFGATGVKRLRSIGMIESVPGMKCLDMNAAEDAIVKHTREVVPGMIVTGMEVAEIDGSPRMGPTFGAMMISGQKAAHLALKALGLPNELDGNYKPNVHPELVLASTDDETASA
What is the function of this protein?
Involved in biosynthesis of the thiamine precursor thiazole.  Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate.  The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate.  The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme.  May have additional roles in adaptation to various stress conditions and in DNA damage tolerance.
What are the official names of this protein?
Thiamine thiazole synthase 1, chloroplastic, Thiazole biosynthetic enzyme 1.
What is the protein family that this protein belongs to?
Belongs to the THI4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CARB2_AQUAE
Sequence: MSKKVVILGSGPNRIGQGIEFDYACVHAVFSLQEEGYYAVMVNCNPETVSTDYDTADKLYFEPIVFEHVMDIIEREKPEGVILQFGGQTPLKLALPLQKNGVKILGTKPESIDKAEDRELFRELIIELGLKQPPSGTARTKEEALKIAKEIGFPVLVRPSYVLGGRAMRIVYDEEELKEYLEEAVSVSHERPVLIDKFLDNSIELDVDAVSDGKDVLIGAVMEHIEEAGVHSGDSATSIPPYSLSKEIVEEVKEQTRKLAVALEVKGLINVQYAVQNNEVYVLEVNPRASRTVPFVSKSIGYPLAKIATKVAIGKSLREILPEVFERLEKGEAHFASDFLPKEKKIFSVKEVVFPWKRFPEVDPILGPEMKSTGEVMGIDKEFGLAYYKAQLSAGYRLPEKGNLFISVADRDKPKILELAKEFEKLGFGIYATSGTYKFLKEHGVNAKRVLKVSEGRPNVVDMIINGEIHLVINTPSGKREKSDAYYIRRACVQFNVPYYTTMRAGYAVLEAIKSIKKLKEEGKGLSVHSLQEIYNI
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, C-terminal section, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.