PharMolix/UniProtQA huggingface dataset:
Protein: CEAM5_MOUSE
Sequence: MEASSVLPCKWCTHLQGLLLTASFLTCCHLPTTAQITIELEPPQVIEGENVLIRVNNLTENLITLAWFRGMRIKSPQIGQYTPATKVTVLGPGHSGRETLYSNGSLQIYNVTQEDIGFYSLRIINKHAEIVSITSIYLNVYSSLWTCEHPSPHAKLTIESVPPGISEGGSVLLLVKNLPQNLLSLFWYKGVIAVKKFEIARHIKATNSSVPGPAHTGRETVFSNGSLLLQEVMQSDTGFYTLRTMSTDLKDEVAHVQLYMDTYLLTCYHPLQVKIESLPQNVAVGKTVLLLVHNLPEDFQAFFWYKSAYRRDTYKIAEYKRAMDATILGSAYSSREFIYNNGSMLIIDVTEDDAGYFLLEILREDLKIEKAYIQLHVNSFVSNSKDSASTARLSIESVPPSIVEGGSVLLLVHNLPKNLQSLFWYKGMIAEKKSELIQHIIATSSSLPGPAHSGRETVYNNGSLLLQRVMQNDTQFYTLQTMDTDLKYEVAHVQLQLDTSLSTWYHPLQVKIESLPRNVAVGKSVLFLVHNFPEVFRAFSWYKPAYKSHTSKIVEYHRFTDSATVGAAYRGIEVIFTNGSMVMIDVTEDDAGFYMLEILREDFKVEKAYVQLHVNSFVPNSKVSVSTARLSIESVPPSIVGGESVLLLVHNLPKNLQSLFWYKGVIAEEKSELIQHIIATSSSLPGPAHSGRETVYSNGSLLLQRVMQNDTGFYTLLTMSTDLKDEIAHVQLQLDTSTCCSLLTSDQLIIVPVPRNIAVGKSVLLLVCNVPKDVQTIFWYKSVYRTDIFKIAEYSRSMESTIWGLAHSGKEMVYTNGSLLIQNVTEHDAGLYMLEILHKDYKLERAHVQVHVNNPVSWPFVRVTDTTVRVQSSVVFTCFSADPGVSIRWLFNKQSLQLTERMTLSPSKCQLSIDPVWREDAGKYQCEVSNPVSSKSSLPVRLAVIEE
What is the function of this protein?
Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression.  Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6.  Plays a role as an oncogene by promoting tumor progression; induces resistance to anoikis of colorectal carcinoma cells.
What are the official names of this protein?
Carcinoembryonic antigen-related cell adhesion molecule 5, Pregnancy-specific glycoprotein 30.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. CEA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Apical cell membrane. Cell surface. Note=Localized to the apical glycocalyx surface.
Protein: RS7_RALSO
Sequence: MPRRREVPKREILPDPKFGNVEVAKFMNVLMLDGKKSVAERIVYGAFDQIEKKAGKAPIEVFTLAIGNIKPVVEVKSRRVGGANYQVPVEVRPSRRLALAMRWLREAAKKRSEKSMALRLAGELLEASEGRGGAMKKRDEVHRMAEANKAFSHFRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: NUOC_FRAP2
Sequence: MSARLQDHFNNVEKILNGFSVECYVAYGEINISIKDQRDIHLVLKKLKKEYHFKQLTDITAVDYLTYGQSDWQVGKVVSQTGFSRGRQQGFKTADVNNRFEIIYQLLSMANNVRVRVKCKLKDAQIIMVDSVEDLWPSANWAEREVYDMFGIYFNNHPDLRRVLTDYGFVGHPLRKDFPQTGYVEMRYDENLGKVVYEPVEIDDRVNAPRVIRNQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y903_METJA
Sequence: MGGGGMKKIVLALLLLLLPVVCGDVSVYKVWSPYDPPNSPILHVDISEQVLYLGVVNKDEYEHDVIVKVECNGKTWGSGLIPLPPNSHIEKIVEVRVPISDDKEHDAKISLIENGKTIASTTVKVRPYFPVDVKNVTCEDSYKIGNTEVCYSNWFDITLKSNPTAKSDYIAKVWINVKDGDNIIYNGKNDFKTVYIPLGEEVTVSFKVPKIVLDKEKFTVETNVEIMNVTHTIDGVEETIQRRDDSGIYYDYKSVTKYYYFPVVIKNVELYRKIDENTSEFVKNFYDSANILDDEIRDILSDKYLQKDDVLPRYYVIDDPTLAILKITVENKYDRDVKAKLTVKYDNVIFTKIINIDKKEKKDVFIPIYTKKGSKNIVVTINPIDADTLIFNRSYSINIDPKPIPPVIIEKIILPKDEEIGEETNISGYVIIGKRYNMTIFIKNIYNKTLSGKITIDDNFKDGIANYSKEIPFTIEPHQIKEINVPIIFYKEVNGDLKITVSVKGGAKDYTSLAHFYAISPIGIVRIYYNNTLLLGKINVIKENSGIYSAKPIAGFNNTCVVILRNNLNSKVDCDVWIEVIDKDGKVRAKSGIKTVKLDNYSEAKVAFPIFFEEGFEGYTVAHIIPKSVENVDIIYTEVMEST
What are the official names of this protein?
Uncharacterized protein MJ0903.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: IOLG_SALPB
Sequence: MTLKAGIVGIGMIGSDHLRRLANTVSGVEVVAVCDIVAGRAQAALDKYAIEAKDYNDYHDLINDKDVEVVIITASNEAHADVAVAALNANKYVFCEKPLAVTAADCQRVIEAEQKNGKRMVQIGFMRRYDKGYVQLKNIIDSGEIGQPLMVHGRHYNASTVPEYKTPQAIYETLIHEIDVMHWLLNEDYKTVKVYFPRQSSLVTTLRDPQLVVMETTSGINIVVEVFVNCQYGYDIHCDVTGEKGMAELPTVASAAVRKAAKYSTDILVDWKQRFIDAYDIEFQDFFDRLNAGLPPAGPTSWDGYLAAVTADACVKSQETGNTEIVELPSKPDFYK
What is the function of this protein?
Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).
What are the official names of this protein?
Inositol 2-dehydrogenase, Myo-inositol 2-dehydrogenase, MI 2-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
Protein: APOE_DASPU
Sequence: MKVLWAALVVTLLAGCQADVEPELEVQEPAVWQSGQPWELALGRFWDYLRWVQTLSEQVQEELLSSHVTQELTLLMEDTMKEVKAYKSELEQELAPMAEDTKARLSKELQAAQSRLRADMEEVLNRLSQYRGEVQTMMGQSGEELRARLAAHLRKLRKRLLRDVEEVQKRMDVYRAGAQEGAERSVSAIRERMGSLVEEGRLQSLPSQPLRERAQAWGEQMRGRLEKVGSQARDRLEEVREQMEEVRGKVEEQAEAFQARFKSWFEPMMEDMRRQWADLIEKVQVAVGASTAAPSQKS
What is the function of this protein?
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids.  APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance.  Apolipoproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma.  As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL).  It also binds a wide range of cellular receptors including the LDL receptor/LDLR, the LDL receptor-related proteins LRP1, LRP2 and LRP8 and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles.  Finally, APOE has also a heparin-binding activity and binds heparan-sulfate proteoglycans on the surface of cells, a property that supports the capture and the receptor-mediated uptake of APOE-containing lipoproteins by cells.  A main function of APOE is to mediate lipoprotein clearance through the uptake of chylomicrons, VLDLs, and HDLs by hepatocytes.  APOE is also involved in the biosynthesis by the liver of VLDLs as well as their uptake by peripheral tissues ensuring the delivery of triglycerides and energy storage in muscle, heart and adipose tissues.  By participating in the lipoprotein-mediated distribution of lipids among tissues, APOE plays a critical role in plasma and tissues lipid homeostasis.  APOE is also involved in two steps of reverse cholesterol transport, the HDLs-mediated transport of cholesterol from peripheral tissues to the liver, and thereby plays an important role in cholesterol homeostasis.  First, it is functionally associated with ABCA1 in the biogenesis of HDLs in tissues.  Second, it is enriched in circulating HDLs and mediates their uptake by hepatocytes.  APOE also plays an important role in lipid transport in the central nervous system, regulating neuron survival and sprouting.
What are the official names of this protein?
Apolipoprotein E, Apo-E.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix. Note=In the plasma, APOE is associated with chylomicrons, chylomicrons remnants, VLDL, LDL and HDL lipoproteins. Lipid poor oligomeric APOE is associated with the extracellular matrix in a calcium- and heparan-sulfate proteoglycans- dependent manner. Lipidation induces the release from the extracellular matrix.
Protein: SMU1_DANRE
Sequence: MSIEIESADVIRLIMQYLKENSLHRTLAMLQEETTVSLNTVDSIESFVADINSGHWDTVLQAIQSLKLPDKTLIDLYEQVVLELIELRELGAARSLLRQTDPMIMLKQTQPERYIHLENLLARSYFDPREAYPDGSSKEKRRAAIAQALAGEVSVVPPSRLMALLGQSLKWQQHQGLLPPGMTIDLFRGKAAVKDVEEERFPTQLARHIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMSFSRDTEMLATGAQDGKIKVWKIQSGQCLRRYERAHSKGVTCLSFSKDSTQILSASFDQTIRIHGLKSGKCLKEFRGHSSFVNEATLTPDGHHAISASSDGTVKVWNMKTTECTSTFKSLGTSAGTDITVNNVILLPKNPEHFVVCNRSNTVVIMNMQGQIVRSFSSGKREGGDFVCCTLSPRGEWIYCVGEDYVLYCFSTVTGKLERTLTVHEKDVIGIAHHPHQNLIGTYSEDGLLKLWKP
What is the function of this protein?
Involved in pre-mRNA splicing as a component of the spliceosome (By similarity).  Required for normal accumulation of ik (By similarity).  Required for normal mitotic spindle assembly and normal progress through mitosis (By similarity).
What are the official names of this protein?
WD40 repeat-containing protein SMU1, Smu-1 suppressor of mec-8 and unc-52 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat SMU1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus speckle. Note=Colocalizes with srsf1 in nuclear speckles.
Protein: TSR3_METS3
Sequence: MKVTVFHANECDRKKCTSIKMEKLGKCKLVYNINKIPSGAVVLNPFAQKAVSYEDYRYVHRRGVVGLDCSWNEVSSSKKFFSLSKYHRSLPFLIATNPVNYGKPCILSTVEAVSATLYITRFKDEAKDILDGFKWGHTFLELNHDLLEAYSEADTSKDVVRVQNEFLESKE
What is the function of this protein?
Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine corresponding to position 914 in M. jannaschii 16S rRNA.  It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).
What are the official names of this protein?
16S rRNA aminocarboxypropyltransferase.
What is the protein family that this protein belongs to?
Belongs to the TDD superfamily. TSR3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDE6C_CHICK
Sequence: MGEVNKDAVEKYLENNPQFAKEYFDRKMRAEVLGSIFQVSPGDVKEGVSFKDMSRLEECNILFELLTEIQDEAGSMEKIVHKTLQRLSQLLARDRCSMFICRSRNGIPEVATRLLNVTPTSKFEDNLVNPDKETVFPLDIGIAGWVAHTKKFFNIPDVKKNNHFSDYLDKKTGYTTVNMMAIPITQGKEVLAVVMALNKLNASEFSKEDEEVFKKYLNFISLVLRNHHTSYLYNIESRRSQMLLWSANKVFEELTDIERQFHKALYTIRMYLNCERYSVGLLDMTKEKEFYDEWPIRLGEAEPYKGPKTPDGREVNFYKIIDYILHGKEEIKVIPTPPADHWCLISGLPTYVAENGFICNMMNAPADEYFTFQKGPVDETGWVIKNVLSLPIVNKKEEIVGVATFYNRKDGKPFDEYDEQIIETLTQFLGWSVLNTDTYDKMNKLENRKDIAQEMLMYQTKATPTEVESILKYKEKLNVKSIEECDEKDLIRILKEELPDPKDLELYEFRFSDFPVTEHGLITCGIRLFFEINVVEKFKVPAEVLTRWMYTVRKGYRDITYHNWRHGFNVGQTMFTLLMTGRIKKYYTDLEAFAMVAAAFCHDIDHRGTNNLYQMKSAAPLAKLHGSSILERHHLEYSKTLLQDESLNIFQNLNKRQFETVLHLFEVAIIATDLALYFKKRTMFQKIVDAIEKMETEEEAIKYISIDPTKKEVIMAMMMTGCDLSAITKPWEVQSKVALMVANEFWEQGDLERTVLQQQPIPMMDRNKGDELPKLQVGFIDFVCTFVYKEFSRFHKEITPMFDGLQNNRVEWKTRADEYEEKMKVIEEQKKKEEEAAAKKAENAAGGGGGGEDGKSKTCIVL
What is the function of this protein?
As cone-specific cGMP phosphodiesterase, it plays an essential role in light detection and cone phototransduction by rapidly decreasing intracellular levels of cGMP.
What are the official names of this protein?
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha', cGMP phosphodiesterase 6C.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: AF1L1_DANRE
Sequence: MEINSKPMELLVTELNMLLKLLDHETLSCATEEKKMAVKNLLRQLQPSVTAKDYMYVNTSVYRNGTSFVESLFETFDCDLGDLKVEMEDQKKEPEANHTVTKPSKTDSPPPLPNTPPPEDYYEEAVPLSPGKMPEYITSRSSSSPPNSIEDGYYEDAENNYPTTQVNGRRKNSYNDSDALSSSYESYDEEEEEKGQRLTHQWPSEENSMAPVRDCHICAFLLRKKRFGQWAKQLTVIRENRLQCYKSSKDQSPYTDIPLSLCSVIYVPKDGRRKKHELRFTLPGGEALVLAVQSKEQAEKWLHVVRDVTGQGNGLDSPSSPMIPKKIELDKWCSAEKQTSDSDSMPSGESARDIRENGKPKRGALSELTGTVSRAAGRKITRIISFSKRKPPLPGDSRSSFDHDPRCGYVGVLVNRCWREHWCRVRAGSLYLYQEKGEQRVPHTTVGLKGCEVVPGLGPKHPFALRILKGGAEVAALEASCSEDMGRWLGVLLAETGSSADPESLHYDYVDVETIANIRTAARHSFLWATSTGSRTYDEVPFETEQENERLRGRAQTKRRSSFSSSDTGKPSPQITLKRHGSNANQYGRYGKTRAQEDARRYLKEKEDLETEIDSIRTALVALRKKKREAKEKMKSATDKQKLALEECVTKLEDSCRVKEGDRVDLELKLTQVKENLKKSLAGGEMEVPTESKPAHKTQRTEAQYMESFLPVNCASEMRKRPPSIYASTKGNVMQKAKEWESKKGT
What is the function of this protein?
May be involved in podosome and invadosome formation.
What are the official names of this protein?
Actin filament-associated protein 1-like 1, AFAP1-like protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, podosome. Cell projection, invadopodium. Cytoplasm, cytoskeleton, stress fiber.
Protein: TUSE_PECAS
Sequence: MLEFEGRTIATDAQGYLMDSTAWSEALAPVLAEQEGIALTEPHWEVVRFVRNFYQEFNTSPAIRMLVKAMAQKYGEEKGNSRYLYKLFPKGPAKQATKIAGLPKPVKCI
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.  Could accept sulfur from TusD (By similarity).
What are the official names of this protein?
Sulfurtransferase TusE, tRNA 2-thiouridine synthesizing protein E.
What is the protein family that this protein belongs to?
Belongs to the DsrC/TusE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNCB_HERAR
Sequence: MPPIVNNLLENDLYKFTMWQALLHSHPEAQTEYEFVCRNAPAYPLSELKADVERELDHLCTLAFRDDELLYLRSLRFMKSDFVDFLTVFRFQRKFITVAADGPALRIRAIGPQVHVMGFEIFVLCIVNELYLRRFDQQASLTEARRRLQEKIRLLKNFGKEATRKNPFEFFDFGVRRRFSAAWHEEVVVTLAREVPQYFTGTSNVHLAKKYGLTPIGTMAHEYLQAYQSFGVRLRDFQKAALEDWVQEYRGDLGIALTDVVGMDAFLADFDLYFAKLFDGLRHDSGDPIEWGEKALAHYARLRIDAGSKRLVFSDALDLPGAFSLYRHFADRTLTGFGIGTNLSNDTGIPALNIVMKLMACNGQPVAKLSDSAGKTLCRDETFLAYLRQVFHHPAVK
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: ARGR_BACCQ
Sequence: MNKGQRHIKIREIIANKEIETQDELVDILRNEGFNVTQATVSRDIKELHLVKVPLHDGRYKYSLPADQRFNPLQKLKRNLVDSFVKLDTAGHMLVLKTLPGNAHSLGALIDHLEWDEIIGTICGDDTCLIICRTPEDTGVVSDRFLNML
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP2_BAVJK
Sequence: MPRKKEQASKSENEKQTSNVQAQDFKTAIQPDTATAQLIKTYSNPKQRGDKGEIVYDGGQSSKLAEVVDQTTEPHNADGAVKDGRIAPVKLDLEKQKLDKLKLFEASPFDPLTVKNNQDVVDKLYATQSSSIQEVVPTKTFATELQFGVTSEDMAKIYGAVVAVSKNVNSSVTYEVKRGTHELIKVPTIPHNLVLIQSDNGKHALIKEDLGQWPVETGVSLVNQAGVFAVQLANKLGIDKPFVLDAGSNYFTDTSFIDTRKYCTDGLSPREIQKALNRQRAYYDRPELTIAENRTLLSQSIVYPDVDGNDVSVIFSGAMSHAIFTYAQSQWSKNIIRLDDYIREITLTVPKHYRPRRFKEIEHTHGYVYRELNQGSLLPLVDANLKEASSYYFKKLMPSISNVPVDARTLQSATSALAADTGLVDRAPHVSMLTNRLTTANASSVRAITVLTCMFKQFRIGMTYSPDPNIMDVAAATCMLLFRPAQSISDEQYRYCLQTMAVFLTNTTYDIVNNDTVDVLKTKLRNQGWPLVERYNAIEVDMSVEPLRSPGQVGRYYNPFNIDPLTKKHVEDRLEEFPNQVQVGRFRNVSNNAVGAALAAFLRACRDKTSANWKGYSILVSRYRSLIPNELFESLRNISGEYNINPQDEHSFFFALAQINADEEFTGVIDKESAEYLDEYATLAREISNSLTLVKAAFGPLERTSGSILNHANNLNKVINRVFADKPLISETMLKILTIDGTTGKDGYRNWLDKLVGHNYPVYVEPVVNIVNFISARFIADSSYFGYTNEIMIMPNHITVPVDDRFGFRDSPFCMSLPRTIMGNEVRRISYSVFSMMEDIDEVISEGFILYDAYFNFTYDIMTTDGVTRLKEDILVVTDTGNDIKPIHFYIYFENKNDKKLRYESKMNVNYRLYIKTPACLLPLNDYMRAQHEYVSPSSSRVYIKDPAVVYTRS
What is the function of this protein?
Self-assembles to form an icosahedral capsid with a pseudo T=2 symmetry, about 60 nm in diameter, and consisting of 120 VP2 subunits.
What are the official names of this protein?
Major inner capsid protein VP2.
What are the subcellular locations of this protein?
Virion.
Protein: PALI_ASHGO
Sequence: MMGGMSVVEWLLLGSTTLALLFQSFATFSVPLSNGVTLSHFNGYKFGVFGWCDTTHTHCTPLKLGYSAEDGFLFAGQDELSLPTQAKYSLSKLLVVHPLALCSMVVLWLMVVLSQCYKHSDRRLTIIILWSFLTYMETLLCFLVDVLLFVPYLDWPGWLMLVSAVLVVFSSSIACLRRRTLTSQRIEKGAKEDLELYPLYGGALGAGVVSDSESPHRPYTEGSIISVTSRASSRLLPSASELETPREELTLMDPSIKCHIERSPMS
What is the function of this protein?
Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH.
What are the official names of this protein?
pH-response regulator protein palI/RIM9.
What is the protein family that this protein belongs to?
Belongs to the palI/RIM9 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATPD_FRATO
Sequence: MTNISVIAKPYAKAAFEFANEHNLLQQWSKLLQTFSELIKDKSVAAIVSSPTISQIEVVDALKKQLDENFFNFLALIAENKKMLIMPEIADQFESIKNIHNNVRVADVTLAYATDKNILDSLKTSLEKKFGCTIDMHINIDPAIIGGAVVKVGDTVIDSSVSGHLEKLKSILLS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HEM3_MYCTA
Sequence: MIRIGTRGSLLATTQAATVRDALIAGGHSAELVTISTEGDRSMAPIASLGVGVFTTALREAMEAGLVDAAVHSYKDLPTAADPRFTVAAIPPRNDPRDAVVARDGLTLGELPVGSLVGTSSPRRAAQLRALGLGLEIRPLRGNLDTRLNKVSSGDLDAIVVARAGLARLGRLDDVTETLEPVQMLPAPAQGALAVECRAGDSRLVAVLAELDDADTRAAVTAERALLADLEAGCSAPVGAIAEVVESIDEDGRVFEELSLRGCVAALDGSDVIRASGIGSCGRARELGLSVAAELFELGARELMWGVRH
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: LEGB_PEA
Sequence: GNSVLSGFNVEFLAHSLNTKEDTAKRLRSPQDERGQIVKVEDGLHIISPELQEEEEQSHSQRKEEEEEEQEQRHRKHSKKEDEDEDEEEEEEREQRHRKHSEKEEEDEDEPRSYETRRKWKKHTAEKKRESHGQGEEEEELEKEEEEEEEIQRQHSKGRKNGLEETICSAKIRENIARPSRGDLYNSGAGRISTVNSLTLPILRNLRLSAEYVLLYRNGIYAPHWNINANSLLYVIRGEGRVRIVNSEGNKVFDDKVSLGQLVVVPQNFVVAQQAGNEEGFEYVVFKTNDRAAVSHVNQVFRATPGEVLANAFGLRHSQVAQIKSNGNRGPLVQPQSQ
What is the function of this protein?
This protein found in the seeds of many leguminous and non-leguminous plants is the source of sulfur-containing amino acids in seed meals.
What are the official names of this protein?
Legumin B.
What is the protein family that this protein belongs to?
Belongs to the 11S seed storage protein (globulins) family.
Protein: SYY_BUCAI
Sequence: MSEFNFISRLHNRGLISHITNEDNLSKLIENKSISLYCGFDPTEESLHIGHLLPLIMLKRFQIAGHRPIILIGGATSLIGDPSFKEKERVFNSNYNVNIWTEKITKQISCFLDFNCGKNSAVLLNNNTWFKQINILSFLRDVGKYFSVNTMINRAAVKQRITRPDQGISFTEFSYNLLQAYDFFILNQQYQADLQIGGADQWGNISSGMHLIHRKTKRVVYGLTVPLLIQSNGIKFGKTESGTIWLDSNKTSPYKFYQFWMNIEDANVYYFLKLFTFIKVSEINKLEKNKNIKNQIINDKSLLAKHITQLVHGKEKLLAAERITKFLFLKNTTHIEESDLQQLKQDGIPFIEVSNVKDLQEALVLTSLAQSRTQAKNMIISNSISINTEKIRKNHIFHEKDKLFGKFTLLSRGKKQHSLLCW
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXH_BORPA
Sequence: MNKLALQGPLWLASDLHLGPATPATAEAFLGLLQAAADEASALLLPGDIFDAWIGDDVIRAAPPWLAAVLQGIRAAAGRIPVYLGRGNRDFLIGQELADALGAHLLPEPVLLETDYGRILLTHGDEYCTDDSAYQQFRAMVRNPQWQAQFLAMSIPERLAMAEQARGESQAANQAKSMEIMDVNPASVEAALREADVDVLVHGHTHRPARHVLSVDGRKRERWVLPDWDCDHADPPRGGWLVIDRDGLQCFDLVEDED
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: AOP3C_ARATH
Sequence: MGSCSPQLPLICLSDQTLKPGSSKWVKVRSDVRKALEDYGCFEAKIDQVSMELQGSVLKAMQELFALPTEAKQRNVCPKPFTGYLSHNGLSESFGIKDANILEKAHEFTQQLWPEGNKSISKMIQLYAEKLAELDMMVRRLILESYGIEYFIDEHLNSTYYRMRLMKYIARPDNDITAAVGANVDNGANDNADGDANVNDDGASIGVKVNVDVGDDVNDNDSVNIGVGVDINVETNVNGDLDAEANGDATAWVVGAVSGNASVGAKEANVDAELGLPSHTDKSLTGIIYQHQIDGLEVKTKEGKWIRVKPAPNTVIVIAGDALCALMNGRIPSPYHRVRVTEKKKTRYAAALFSNPKEGYIIDSPKELVDEKHPRAFKPFDFVDLFNFYHTEAGRRAPSTLQAFCGVSAGK
What is the function of this protein?
2-oxoglutarate-dependent dioxygenase involved in glucosinolates biosynthesis.  Catalyzes the conversion of methylsulfinylalkyl glucosinolates to hydroxyalkyl glucosinolates (By similarity).
What are the official names of this protein?
2-oxoglutarate-dependent dioxygenase AOP3.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: E4PD_YERPN
Sequence: MAIRIAINGFGRIGRSVLRALYESGRRAEISVVAINELASAEGMAHLLKYDSSHGRFAWDVRQECDSLYVGDDIIRLIHQSEIEQLPWSELGIDVVLDCSGVYGSREDGEAHVASGAKKVLFAHPGGHDLDATVVYGVNHQDLRAEHRIVSNASCTTNCIIPIIQLLDIAYGIESGTVTTIHSSMNDQPVIDAYHQDLRRTRAASQSIIPVDTKLAAGITRIFPKFCDRFEAISVRVPTINVTAIDLSVSVTHPVGVAEVNQLLQKAARGAFRGIVDYTELPLVSMDFNHDPHSAIVDGTQTRVSGQHLIKTLVWCDNEWGFANRMLDTTLAMAKSGF
What is the function of this protein?
Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
What are the official names of this protein?
D-erythrose-4-phosphate dehydrogenase, E4PDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_YERPG
Sequence: MKFVDEAAILVVAGDGGNGCVSFRREKYIPNGGPDGGDGGDGGDIYLLADENLNTLIDYRFVKSFRAERGQNGQSRDCTGKRGKDITIKVPVGTRVLDQGTGEIVGDMVRHGQRLMVAKGGFHGLGNSRFKSSVNRAPRQKTMGTEGETRELMLELLLLADVGMLGLPNAGKSTFIRAVSAAKPKVADYPFTTLIPSLGVVRMDYEQSFVIADIPGLIEGASDGAGLGIRFLKHLERCRVLLHLVDLAPIDESDPAENAKVIVNELQQYSENLAEKPRWLVFNKIDLIDPEEAEKRAKAIVETLGWEGKYYMISAANRDNVNALCWDVMSFLNSQPKAMAIAESVPEKVEFMWDDYHREQLAEVEAEAEDDWDDDWDEEDDDGVEIIYER
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRP4_IGNAA
Sequence: MYEKEAISLQTSKRILVVPGDSVQISQDVVIDPQQILYLYKKDDNTFISTITALLDFENIDDKKKLRVIPLKGRYIPREGDIVIGIVVDVTLSSWIIDINSPYLSVLNASDYLGRSFNPLTDNIRKYLEIGDVVVGKIATFDRSRGPILTVQDKGLGKVVDGSLIEIEPIKVARVIGKKKSMLNMLIEQTKCDILVGNNGRIILRCPNPELEYIAILAIKKIESEAHTTGLTERIREFIIEEKVKRGLIKYEV
What is the function of this protein?
Non-catalytic component of the exosome, which is a complex involved in RNA degradation.  Increases the RNA binding and the efficiency of RNA degradation.  Confers strong poly(A) specificity to the exosome.
What are the official names of this protein?
Exosome complex component Rrp4.
What is the protein family that this protein belongs to?
Belongs to the RRP4 family.
What are the subcellular locations of this protein?
Cytoplasm.