PharMolix/UniProtQA huggingface dataset:
Protein: RPOC1_ORYSJ
Sequence: MIDQYKHQQLQIGLVSPQQIKAWANKTLPNGEVVGEVTRPSTFHYKTDKPEKDGLFCERIFGPIKSRICACGNSRASGAENEDERFCQKCGVEFVDSRIRRYQMGYIKLACPVTHVWYLKGLPSYIANLLDKPLKKLEGLVYGDFSFARPSAKKPTFLRLRGLFEDEISSCNHSISPFFSTPGFTTFRNREIATGAGAIREQLADLDLRIILENSSVEWKELEDEGYSGDEWEDRKRRIRKVFLIRRMQLAKHFIQTNVEPEWMVLCLLPVLPPELRPIVYRSGDKVVTSDINELYKRVIRRNNNLAYLLKRSELAPADLVMCQEKLVQEAVDTLLDSGSRGQPTRDGHNKVYKSLSDVIEGKEGRFRETLLGKRVDYSGRSVIVVGPSLSLHQCGLPLEIAIKLFQLFVIRDLITKRATSNVRIAKRKIWEKEPIVWEILQEVMRGHPVLLNRAPTLHRLGIQAFQPTLVEGRTICLHPLVCKGFNADFDGDQMAVHLPLSLEAQAEARLLMFSHMNLLSPAIGDPICVPTQDMLIGLYVLTIGNRRGICANRYNSCGNYPNQKVNYNNNNPKYTKDKESLFSSSYDALGAYRQKQICLDSPLWLRWKLDQRVIGLREVPIEVQYESLGTYREIYAHYLVVGNRKKEIRSIYIRTTLGHISFYREIEEAIQGFSQAYSYTI
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', PEP, Plastid-encoded RNA polymerase subunit beta', RNA polymerase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CAPSD_HBOC4
Sequence: MPPIKRQPGGWVLPGYKYLGPFNPLENGEPVNKADRAAQAHDKSYSELIKSGKNPYLYFNKADEKFIDDLKDDWSLGGIIGSSFFKLKRAVAPALGNKERAQKRHFYFANSNKGAKKTKNNEPKPGTSKMSENEIQDQQPSDSMDGQRGGGGGATGSVGGGKGSGVGISTGGWVGGSYFTDSYVITKNTRQFLVKIQNNHQYKTELISPSTSQGKSQRCVSTPWSYFNFNQYSSHFSPQDWQRLTNEYKRFRPKGMHVKIYNLQIKQILSNGADTTYNNDLTAGVHIFCDGEHAYPNATHPWDEDVMPELPYQTWYLFQYGYIPVIHELAEMEDSNAVEKAICLQIPFFMLENSDHEVLRTGESTEFTFNFDCEWINNERAYIPPGLMFNPLVPTRRAQYIRRNNNPQTAESTSRIAPYAKPTSWMTGPGLLSAQRVGPATSDTGAWMVAVKPENASIDTGMSGIGSGFDPPQGSLAPTNLEYKIQWYQTPQGTNNNGNIISNQPLSMLRDQALFRGNQTTYNLCSDVWMFPNQIWDRYPITRENPIWCKKPRSDKHTTIDPFDGSLAMDHPPGTIFIKMAKIPVPSNNNADSYLNIYCTGQVSCEIVWEVERYATKNWRPERRHTTFGLGIGGADNLNPTYHVDKNGTYIQPTTWDMCFPVKTNINKVL
What is the function of this protein?
Capsid proteins self-assembles to form an icosahedral capsid with a T=1 symmetry, about 26 nm in diameter, and consisting of 60 copies of three size variants of the capsid proteins, VP1, and VP3, which differ by the presence of an N-terminal extension in the minor protein VP1.  The capsid has a channel at the 5-fold axis and there are densities extending the 5-fold axis into the interior of the capsid (PubMed:28331084).  The capsid encapsulates the genomic ssDNA (Probable).  Binding to the host receptors also induces capsid rearrangements leading to surface exposure of VP1 N-terminus, specifically its phospholipase A2-like region.  The additional N-terminal region of isoform Minor capsid protein VP1, called VP1u, may serve as a lipolytic enzyme to breach the endosomal membrane during entry into host cell and might contribute to virus transport to the nucleus (By similarity).
What are the official names of this protein?
Minor capsid protein VP1.
What is the protein family that this protein belongs to?
Belongs to the parvoviridae capsid protein family.
What are the subcellular locations of this protein?
[Isoform Minor capsid protein VP1]: Virion. Host nucleus. Host cytoplasm. Note=Slightly detected in the cytoplasm, mainly seen in the nucleus. SUBCELLULAR LOCATION: [Isoform Minor capsid protein VP2]: Virion. SUBCELLULAR LOCATION: [Isoform Major capsid protein VP3]: Virion. Host nucleus. Host cytoplasm. Note=Slightly detected in the cytoplasm, mainly seen in the nucleus.
Protein: MIDN_MOUSE
Sequence: MEPQPGGARSCRRGAPGGACELNTATESAAPMSLAIHSTTGTRYDLSVPHDETVEGLRKRLSQRLKVPKERLALLHKDTRLSSGKLQEFGVGDGSKLTLVPTVEAGLMSQASRPEQSVMQALESLTETQVSDFLSGRSPLTLALRVGDHMMFVQLQLAAQHAPLQHRHVLAAAAAAAAAARGDSSVATPVSSPCRPVSSAARVPPVSSSPSSPVSPSPVTAGSFRSHAASTTCPEQMDCSPPASSSSTSTPGSSPTPRSRKPGAVIESFVNHAPGVFSGTFSGTLHPNCQDSSGRPRRDIGTILQILNDLLSATRHYQGMPPSLTQLRCHAQCSPASPAPDLTPKTTSCEKLAATSSTSLLQGQSQIRMCKPPGDRLRQTENRATRCKVERLQLLLQQKRLRRKARRDARGPYHWTPSRKAGRSDSSSSGGGGGPSEATGLGLDFEDSVWKPEVNPDIQSEFVVA
What is the function of this protein?
Facilitates ubiquitin-independent proteasomal degradation of polycomb protein CBX4 (PubMed:27326929).  Plays a role in inhibiting the activity of glucokinase GCK and both glucose-induced and basal insulin secretion (By similarity).
What are the official names of this protein?
Midnolin, Midbrain nucleolar protein.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol. Nucleus, nucleolus. Note=Detected in the nucleus and nucleolus with no expression in the cytoplasm (PubMed:10974535). However, a later study finds expression in the nucleus and cytoplasm with no expression in the nucleolus (PubMed:24187134).
Protein: ACS_NEOBT
Sequence: MVPISTRSEVQDGLIAQARSLITRIVHNSDDVYGFGTLSCTVYDTAWVALVTKHVNGIKHWLFPESFHYILASQCDDGTWCEDKTAQFDGVLNTIAGLLVLKRYRRDPLQLKVDNRDLDSRIKLATSALHSLLEEWDVSTTNNVGFEIIVPTMLDLLVQEDPSLSFELKGREALTEIREAKMNRFQPELLYQGKLMTLTHSLEALLGRIDYDNVARYTVKGSMFASPSSTAAYLMSASTWDDEAETYLRYTITASTGKGSGGVPGVFPTTYFEYTWILSTLFRAGFQSSELDSPELTAMTDTLLKAFKAFSGAIGLDSGIEPDVDDSAKIVTTLNMLGKPAHARYLCDNFEVETHFRVYPRERDPSFSANCNALAAFLHQPDVEVYSSQILKAASYLCERMWNADEKIDDKWNKSHLYSSFLYTQVMTDLMAITEAGRLDGVFTRELLTRVCVTIFQSCLRAMLKQSHDGSWNQSLEETAYAILHLTEARRLCFFEQISEPLENSIYRGITFLTTIDKPPMEYLWSDKVSYGSAYLAETYVLAARRAAESTSVTNLVGSSIWKDNASTKMHKLVGLFHRTPLLKALPKWELQASMIEASIYQGLLQDARLEVLQRPKVDGGEYLSIIPFTWTSCSNSARTNASASHLWELMALSFFTYQVDEFMEAVAGPAFKGRMTHLHAIIDEAVHCSQNRERTPGECENTNHVTSELLQAVRFILDNPTVRKASPYDRNTLLQELRIFLHAHVTQVEDNASFGRERLTGDKALTSYRSQLYRWVHTISSDHIAGPFCFYYATCLLGATLTAHPPNDCFPKSSQKYLAAATCRHLSCMCRMYNDIGSWNRDHREGNLNCLHFPEFSETTSDDAERKASLLTLAQYERKQWCNALQQLEKEMVHGASEPAAARLAKRRACLIDMFCKVTDLYGQIYVLRDVSSVIKDVVRNGE
What is the function of this protein?
Aphidicolan-16-beta-ol synthase; part of the gene cluster that mediates the biosynthesis of aphidicolin, a specific inhibitor of eukaryotic DNA synthesis and DNA polymerase alpha (PubMed:14745177, PubMed:21897020).  The geranylgeranyl pyrophosphate synthase GGS is required for supplying a sufficient amount of geranylgeranyl diphosphate (GGDP), the general precursor of diterpenes (PubMed:21897020).  The diterpene synthase ACS then catalyzes the conversion of geranylgeranyl diphosphate to aphidicolan-16-beta-ol via the intermediate syn-copalyldiphosphate (syn-CDP) (PubMed:11457369, PubMed:21897020).  In addition to aphidicolan-16-beta-ol, the enzyme produces also low levels of amphidicol-15-ene and amphidicol-16-ene (PubMed:11457369).  The cytochrome P450 monooxygenase P450-2 then catalyzes the two-step hydroxylation from aphidicolan-16-beta-ol to 3-deoxyaphidicolin via a 17,3-deoxyaphidicolin intermediate (PubMed:21897020).  Finally, the cytochrome P450 monooxygenase P450-1 converts 3-deoxyaphidicolin to aphidicolin (PubMed:21897020).
What are the official names of this protein?
Aphidicolan-16-beta-ol synthase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: Y4928_PSEAE
Sequence: MQAAKPLFDYPKYWAECFGPAPFLPMSREEMDQLGWDSCDIIIVTGDAYVDHPSFGMAIIGRLLEAQGFRVGIIAQPDWQSKDDFMKLGEPNLFFGVAAGNMDSMINRYTADKKVRSDDAYTPGGLAGKRPDRASLVYSQRCKEAYSHVPVILGGIEASLRRIAHYDYWQDKVRRSILMDATADILLYGNAERAVVEIAQRLAQGELVSAITDVRGTAFVRRDTPEGWFEIDSTRIDRPGKIDKIINPYVNTQDTAACAIEQEKGAQEDPQEAKVVQLLANPRLTREKTVIRLPSFEKVRNDPVLYAHANRVLHLETNPGNARALVQKHGEVDVWFNPPPIPMSTEEMDYVFGMPYARVPHPAYGKAKIPAYEMIRFSVNIMRGCFGGCTFCSITEHEGRIIQNRSHDSIIREIEEMRDKVPGFTGVVSDLGGPTANMYRIACKSPDIERHCRKPSCVFPGICENLDTDHSSLIELYRKARALPGVKKILIASGLRYDLAVESPEYVKELVTHHVGGYLKIAPEHTERGPLDKMMKPGIGTYDRFKQMFEKFSKEAGKEQYLIPYFIAAHPGTTDEDMMNLALWLKRNGFRADQVQAFYPSPMATATAMYHSGKNPLRKVTYKSDGVTIVKSDQQRRLHKAFLRYHDPKGWPLLREALERMGRADLIGNGKHHLVPTYQPDTGEYQSARRKNSTPAGSKKAGKLLTQHTGLPPRASDGGKPWSKGQQNKATAFAKGKKKSRQPNIPR
What are the official names of this protein?
UPF0313 protein PA4928.
What is the protein family that this protein belongs to?
Belongs to the UPF0313 family.
Protein: POTM1_SOLTU
Sequence: DICTNCCAGTKGCNTTSANGAFICEGQSDPKKPKACPLNCDPHIAYA
What is the function of this protein?
Inhibitor of serine proteases chymotrypsin, papain and trypsin.  Has strong antifungal activity against C. albicans and R. solani.  Has antibacterial activity against the Gram-positive bacterium C. michiganense, but lacks antibacterial activity against the Gram-positive bacterium S. aureus.  Lacks hemolytic activity against human erythrocytes.
What are the official names of this protein?
Potamin-1, PT-1.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I20 (potato type II proteinase inhibitor) family.
Protein: PAT0_SOLTU
Sequence: MATTKSFLILFFMILATTSSTCATLGEMVTVLSIDGGGIKGIIPAIILEFLEGQLQEVDNNKDARLADYFDVIGGTSTGGLLTAMITTPNENNRPFAAAKDIVPFYFEHGPHIFNYSGSIFGPRYDGKYLLQVLQEKLGETRVHQALTEVAISSFDIKTNKPVIFTKSNLAESPQLDAKMYDICYSTAAAPIYFPPHHFVTHTSNGATYEFNLVDGAVATVGDPALLSLSVATRLAQDDPAFSSIKSLDYKQMLLLSLGTGTNSEFDKTYTAEEAAKWGPLRWMLAIQQMTNAASSYMTDYYISTVFQARHSQNNYLRVQENALTGTTTEMDDASEANMELLVQVGETLLKKPVSKDSPETYEEALKRFAKLLSDRKKLRANKASH
What is the function of this protein?
Probable lipolytic acyl hydrolase (LAH), an activity which is thought to be involved in the response of tubers to pathogens.
What are the official names of this protein?
Patatin, Potato tuber protein.
What is the protein family that this protein belongs to?
Belongs to the patatin family.
What are the subcellular locations of this protein?
Vacuole.
Protein: K2C80_MOUSE
Sequence: MAYRSCVVGFSSLSGCEMTPAGSPQPGTSGWGSCGLPGPGFSSRSLTSCRPAGTIPKVTVNPSLLVPLDLKVDPAVQQQKNQEKEEMKALNDKFASLIGKVQALEQRNQLLETRWSFLQGQGSATFDLSHHYETFQGRLQEELRKVSQERGQLEANLLQVLEKVEEFRVRYEDEISKRTDLEFTFVQLKKDLDAECLRRTELETKLKGLQGFLELMRTVYEQELKDLTAQVKDVSVTVGLDSRCHIDLSGIVEEVKAQYDAIAARSLEEAEAYSRSQLEERAARSAEFGNSLQSSRCEIADLNVRIQKLRSQIVSVKSHCLKLEENIKVAEEQGELAFQDAKDKMAQLENALQKAKQDMARQLREYQDLMNTKLALDIEIATYHKLMEGEESRMDLPSATVVSTVKSGCRTTASKSGLTKTSSRKKKNRRGPVIKITEMSEKYLSQESEASE
What are the official names of this protein?
Keratin, type II cytoskeletal 80, Cytokeratin-80, CK-80, Keratin-80, K80, Type-II keratin Kb20.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: TRMD_CUPNH
Sequence: MQFDVITLFPDMFRALTDWGITSRAAKQQRYGLRTWNPRDFTVDNYRTIDDRPYGGGPGMVMLAKPLDDAIDAAVAAQAQAGVPEPHVVLMSPQGKTLSHAKVMELAERPGLVLLCGRYEAIDQRLIDRRVDEEISLGDFVLSGGELPAMALIDAVVRHLPGVLGDAQSAVQDSFVNGLLDCPHYTRPEEYEGVRVPEILLGGHHAEIEKWRRQQALANTASKRPDLIEAARKQGLLTRADEKFLSEWAAKEGRGETPAR
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NOP12_NEUCR
Sequence: MGKTKGLVAPVKKVDPSLDALFATSVGPAKPRPAAKYSEPLPTKSKKAPVPSKKEEDVQDEGDDEELSELDEEYDSEVGIGEDDEDDEAEDNSDSEDEAVATLEVVVEQGKVPEEDGPKRKRKQPDQHDNLEHKYLSKLAEDDEEPAGKRLKADEQSGEKKDTAKAEKKDDDDSESADEVPVHESLAPDAAQNEIEKANRTVFLSNVAVEAVTSRSAKKALMKHMASVLDKEAKPAQKVESIRFRSTAFATAAIPKRAAYIKKSVMEATTKSTNAYVVYSTPAAARLACSKLNGTIVLDRHIRVDSVAHPAPVDHKRCVFVGNLGFVDDETVLQVKVDEDGKEVTEKKKRTKQPMDVEEGLWRVFGKEGGKVESVRVVRDPVTRVGKGFAYVQFCDENAVESAILLNGKKFPPMLPRELRVSRCKAPHKTLRAIEAKKLKAQGAVPETMKKGNNGKKGPGSKKSDYAPKISAEAKTIAGRAEKLLGKFTARQVIGSDKKKTFNKQDRYQANQRRNHASGANTEATGPRVPGAYKSPESFILEGKRASAADGKPKDLKFKGAKKNKAPNAGGGKKKTGRAAARASKWKVQGKGKK
What is the function of this protein?
Involved in pre-25S rRNA processing.
What are the official names of this protein?
Nucleolar protein 12.
What is the protein family that this protein belongs to?
Belongs to the RRM RBM34 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: SECA_SALAR
Sequence: MLIKLLTKVFGSRNDRTLRRMRKAVSLINAMEPEMEKLSDDELKAKTNEFRARIEKGESVESLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNDRCIAEMRTGEGKTLTATLPAYLNALSGKGVHVVTVNDYLAQRDAENNRPLFEFLGMSVGINLPGMPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKKVNKIIPHLIRQEKEDSDTFQGEGHFSVDEKARQVNLTERGLVLIEELLVQEGIMDEGESLYSPGNIMLMHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEGVEIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIRKDLPDLVYMTEAEKIQAIIEDIKERTANGQPVLVGTISIEKSEVVSRELTKAGIKHNVLNAKFHANEAGIVAQAGYPAAVTIATNMAGRGTDIMLGGSWQAEVAALEAPTEEQIAQIKADWQARHDAVLAAGGLHIIGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYSQRNELLDVSDVSDTINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLELPIAEWLDKEPELHEETLRERILAQSIELYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKDPKQEYKRESFAMFAAMLESLKYEVISTLSKVQVRMPEEVEAMEMQRREEAERLALMQQLSHQDDDAAVAADLAAQTGERKIGRNDPCPCGSGKKYKQCHGRLS
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: PP1RB_XENTR
Sequence: MAESSGPTAGGGATSSTVTTESDTQPEHRSLTLKLRKRKPDKKVEWTCDTVDNENLGRRSSKCCCIYEKPRPFGESSSESEDEDDCCESAHCIRGHKKATSGSKETPSSHHDKTGSMQH
What is the function of this protein?
Atypical E3 ubiquitin-protein ligase which ubiquitinates TLR2 at 'Lys-754' leading to its degradation by the proteasome.  Inhibitor of protein phosphatase 1.
What are the official names of this protein?
E3 ubiquitin-protein ligase PPP1R11, Protein phosphatase 1 regulatory subunit 11.
Protein: CENPV_HUMAN
Sequence: MRRSRSSAAAKLRGQKRSGASGASAAPAASAAAALAPSATRTRRSASQAGSKSQAVEKPPSEKPRLRRSSPRAQEEGPGEPPPPELALLPPPPPPPPTPATPTSSASNLDLGEQRERWETFQKRQKLTSEGAAKLLLDTFEYQGLVKHTGGCHCGAVRFEVWASADLHIFDCNCSICKKKQNRHFIVPASRFKLLKGAEHITTYTFNTHKAQHTFCKRCGVQSFYTPRSNPGGFGIAPHCLDEGTVRSMVTEEFNGSDWEKAMKEHKTIKNMSKE
What is the function of this protein?
Required for distribution of pericentromeric heterochromatin in interphase nuclei and for centromere formation and organization, chromosome alignment and cytokinesis.
What are the official names of this protein?
Centromere protein V, CENP-V, Nuclear protein p30, Proline-rich protein 6.
What is the protein family that this protein belongs to?
Belongs to the Gfa family.
What are the subcellular locations of this protein?
Chromosome, centromere, kinetochore. Nucleus. Cytoplasm, cytoskeleton, spindle. Note=Enriched at the nuclear periphery and around the nucleolus (PubMed:12196509). In mitotic cells, localizes to kinetochores from prometaphase to metaphase (PubMed:18772885). At anaphase onset, transfers to the spindle midzone and then to the mid-body in telophase and cytokinesis (PubMed:18772885).
Protein: IF2_SALSV
Sequence: MTDVTLKALAAERQVSVDRLVQQFADAGIRKSADDSVSAQEKQTLLAHLNREAVSGPDKLTLQRKTRSTLNIPGTGGKSKSVQIEVRKKRTFVKRDPQEAERLAAEEQAQREAEEQARREAEEQAKREAQQKAEREAAEQAKREAAEKAKREAAEKDKVSNQQTDDMIKTAQAEKARRENEAAELKRKAEEEARRKLEEEARRVAEEARRMAEENKWTATPEPVEDTSDYHVTTSQHARQAEDENDREVEGGRGRGRNAKAARPAKKGKHAESKADREEARAAVRGGKGGKRKGSSLQQGFQKPAQAVNRDVVIGETITVGELANKMAVKGSQVIKAMMKLGAMATINQVIDQETAQLVAEEMGHKVILRRENELEEAVMSDRDTGAAAEPRAPVVTIMGHVDHGKTSLLDYIRSTKVASGEAGGITQHIGAYHVETDNGMITFLDTPGHAAFTSMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAAGVPVVVAVNKIDKPEADPDRVKNELSQYGILPEEWGGESQFVHVSAKAGTGIDELLDAILLQAEVLELKAVRKGMASGAVIESFLDKGRGPVATVLVREGTLHKGDIVLCGFEYGRVRAMRNELGQEVLEAGPSIPVEILGLSGVPAAGDEVTVVRDEKKAREVALYRQGKFREVKLARQQKSKLENMFANMTEGEVHEVNIVLKADVQGSVEAISDSLLKLSTDEVKVKIIGSGVGGITETDATLAAASNAILVGFNVRADASARKVIESESLDLRYYSVIYNLIDEVKAAMSGMLSPELKQQIIGLAEVRDVFKSPKFGAIAGCMVTEGTIKRHNPIRVLRDNVVIYEGELESLRRFKDDVNEVRNGMECGIGVKNYNDVRVGDMIEVFEIIEIQRTIA
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_CITBB
Sequence: MERTFAIIKPDAVERNVTGKVLAMIEEGGFKIVGMKKIRLSKCQAEGFYYVHKERPFFGDLCAFMSRGPVIALVLEKENAIADWRGLMGATNPANAEAGTIRKALGVSIEENTVHGSDSPESASYEIPYFFNQLELV
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WRK68_ARATH
Sequence: MENVGVGMPFYDLGQTRVYPLLSDFHDLSAERYPVGFMDLLGVHRHTPTHTPLMHFPTTPNSSSSEAVNGDDEEEEDGEEQQHKTKKRFKFTKMSRKQTKKKVPKVSFITRSEVLHLDDGYKWRKYGQKPVKDSPFPRNYYRCTTTWCDVKKRVERSFSDPSSVITTYEGQHTHPRPLLIMPKEGSSPSNGSASRAHIGLPTLPPQLLDYNNQQQQAPSSFGTEYINRQEKGINHDDDDDHVVKKSRTRDLLDGAGLVKDHGLLQDVVPSHIIKEEY
What is the function of this protein?
Transcription factor.  Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity).
What are the official names of this protein?
WRKY transcription factor 68, WRKY DNA-binding protein 68.
What is the protein family that this protein belongs to?
Belongs to the WRKY group II-c family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FLIM_BUCAP
Sequence: MLHTMGKSTNLDNEYKIIYKREKNLDRFLDQNEMKKLEKINKKFIQKIIMIFSSFIKSNIELNFYTVKINSYTNDDKNFKHLYANSLKIETLEKKSFIFFSPNFLSVFIDFLFGGKGNSIIRMDIKKEITYTEHVINKKIVGFIIDAYCESCKDFFYIDIKFLDFNIIKLNKHFFYTNDLFITNYFSFNLNGIKIFLSILIPVSIIKEKNKKIINFLDKNIFSKKTILKENFFIENLSNIELDVTVELIPSYISKHTFDNLREGDVITIEDPGKVTVCIEKKPIFLGKHKIFDEKSIIFLEKFLHQNLEKK
What is the function of this protein?
FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body.  This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity).
What are the official names of this protein?
Flagellar motor switch protein FliM.
What is the protein family that this protein belongs to?
Belongs to the FliM family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein. Bacterial flagellum basal body.
Protein: COBS_MYCSJ
Sequence: MIGSLAGAFAFGTVLPVPTGSTATLGRGVMTALPGVGIVLGAVAAAVLWAGSWAFGPHSALAGLLAVAVLLLATRGMHIDGLSDTVDGLGCYGAPERALRVMRDGSAGAFGAASIVVAVGAQTLAFSMLPGGWSGAVGVVVAVTAGRVAALVACRRGIPAAEGSALGGRVAGTQPAAVVLVWLAAVAALAIPATERIWQGPLTVVVAVGMTALLVRHCVRRFGGITGDVLGAAIEVTTTVVAVGLVIR
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y4606_MYCA9
Sequence: MTGTTTARSDDDSWDIASSVGATAVMVAAARAAETRSASPLIQDPFAQLLVERAGSGAWSVLASDGLRQQLAELDPDADRVMQYAVDYQAVRTRFFDGFFERAAHAGITQVVILAAGLDSRAYRLDWPAGTTVYEIDQPLVLQYKRHTLDAHDVRSACLRREVPVDLRQDWPAALQREGFDVAEPTAWLAEGLLMYLPTEAQDRLFELIVDQSAPGSRIAVEAVGPDNDKRQEFRSKMRAHFDRARKLAGMDGESLDVGSLMYHDENRTDVPQWLAGRGWTVRAIPAEVEMAEAGRPGYIEEDLRGNTLIEAELKG
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase MAB_4606c.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: 3L23X_OPHHA
Sequence: MKTLLLTLVVVTIMCLDLGYTTKCYKTGERIISETCPPGQDLCYMKTWCDVFCGSRGRVIELGCTATCPTVKHHEQITCCSTDNCNPHPKMKQR
What is the function of this protein?
Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission.
What are the official names of this protein?
Long neurotoxin LNTX37.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Long-chain subfamily. Type II alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SSRP_CELJU
Sequence: MAKKNQKSGSNTIALNKKAKFDYELHERFEAGLALTGWEVKSLRAGKGNITDCYVIFKNNEAWLQACQIQPLLSASTHFVTDPFRNRKLLLNRREINRLQEAVEQKGYTVVPIALYWKAHMVKCEIAIAKGKQLHDKRQTEKERDWEREKQRLFQRDQR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: PSBJ_PROMP
Sequence: MSKLKGPDGRIPDRLPDGRPAVAWERRWTEGTLPLWLVATAGGIAVIFVLGIFFYGSYQGVGAG
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein J, PSII-J.
What is the protein family that this protein belongs to?
Belongs to the PsbJ family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: MZB1_RAT
Sequence: MRLPLPLLLLFGCRAILGSFGDRVSLSATAPTLDDEEKYASHMPTHLRCDACRAVAYQMGQHLAKAEAKSHTPDSSGSQELSESTYTDVLDRTCSQNWQSYGVQEVNQMKRLMGPGLSKGPEPSISVMITGGPWPNRLSMTCFHYLGEFGEDQIYEAYRQGHETLEALLCGGTHGSCSQEIPAQREEL
What is the function of this protein?
Acts as a hormone-regulated adipokine/pro-inflammatory cytokine that is implicated in causing chronic inflammation, affecting cellular expansion and blunting insulin response in adipocytes.  May have a role in the onset of insulin resistance (By similarity).
What are the official names of this protein?
Marginal zone B- and B1-cell-specific protein, Plasma cell-induced resident endoplasmic reticulum protein, Plasma cell-induced resident ER protein, pERp1, Proapoptotic caspase adapter protein.
What is the protein family that this protein belongs to?
Belongs to the MZB1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen. Secreted.