PharMolix/UniProtQA huggingface dataset:
Protein: FMT_CAUSK
Sequence: MRIAFLGTPEFSVACLAELVAAGHEIACVYSQPPAPRGRGQDLKPSPVHAFAESLGLPVRTPVSMKTAEEIEAFRALDLDAAVVVAFGQILVRDVLEAPRLGCFNLHASLLPRWRGAAPIQRAIMAGDAVTGVQVMRMSEGLDEGPVLMGEQVRIDALETAGTLHDKLAAVGSRMLPVALAAIERGGARETPQSEEGVTYAKKIKAAEARIDWTRSAAEVDRHIRGLSPFPGAWFEAPSEKGSVRVKALLSRVEDGEGAPGVALDDALLIACGANGEGGAVRLLKAQREGKGAQDAEVFLRGFPLAAGTALA
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: NOP10_META3
Sequence: MRMKKCPNCKNYTLNTICQCGEKTITVKPPRYSPTDKYGKYRRMLKKSIKQ
What is the function of this protein?
Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.
What are the official names of this protein?
Ribosome biogenesis protein Nop10.
What is the protein family that this protein belongs to?
Belongs to the NOP10 family.
Protein: RUVA_METSB
Sequence: MIGKLKGLVDSQGEDYVILDVNGVGYVVHCSSRTLQNLPPQGQATALAIDTQMREDSIKLYGFASETEREWFRLLQSVQGVGAKVALAIQGVLRPGEIVTAIAAQDRAAFARASGVGAKLAARILAELKDKAPALGASLHTLAGAGSEGAGVEAPASGAVSDAISVLVNLGFGRSQAAVAVAASSKALGSGAGAGDLAKRALQELAQSG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: MED31_CRYNB
Sequence: MQALPTILPPPPLPDDSEAPARTPEKHANLVRFQSELEFIQCLAHPQYLHELHIQGYLGKPAFLNYLKYLEYWREPQYVRFIIYPTCLVYLTLLQTELFRSRLGDMGFITELMRVGSRHHATWRVGKPAEDKQSEEKPAVSMAPLDDDEEEDEPERGQETKGKRKKKKSRSGNVGAGQAL
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 31, Mediator complex subunit 31.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 31 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HSLO_GLOVI
Sequence: MADQLVRATAAQGRIRAVGVLSTRLTEEARGRHKLSYVATAALGRTMAAGLLIASNFKQTEARVNLRLQGDGPLGGILVDAGADGTVRGYVKNPQVELPPSPKGKLDVGRAVGANGFLYVVKDLGYGYPFSGTTELVSGEIGDDVTHYLVTSEQVASALMLGVFVGADGVDAAGGLLLQVMPSADGQEDEELAATLERRLASVEGFTPLVRSGKRIPQILEELLGDMGLEIFPEVQLVRFHCHCSPQRVLGALKMMGEAELLDMIEKDGGAEATCHFCNQVYQVKASELETLVEQLRSEREVSSQE
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAB_PROMS
Sequence: MATKFPSFNQGLAQDPTTRRIWYGIATAHDFESHDGMTEEKLYQKLFSTHFGHLAIIALWVAGNLFHIAWQGNFEQFVLDPTHVRPIAHAIWDPHFGSGITEAMTQAGASGPVNIAYSGLYHWWYTIGMRTNEQLFQASIFMSILACWTLFAGWLHLQPKFRPSLAWFKNAESRLNHHLAVLFGFSSIAWTGHLVHVAIPESRGQHVGWDNWLTVLPHPAGLAPFFTLNWGAYAQNPDSLDQVFGTAEGAGTAIFTFLGGLHPQSEALWLTDIAHHHIAIGTVFVIAGHMYRNTFGIGHSLKEITEAHNTRHPNDPHKGSFGINHDGIYETVNNSLHFQLGLALASLGVATSLVAQHMGALPSYAFIARDYTTQSALYSHHQYIAMFLMVGAFAHGAIFFVRDYDPELNKDNVLARVLGTKEALISHLSWVTMLLGFHTLGIYVHNDVVVAFGNPEKQILIEPVFAQFVQAAQGKMMYGFNALLSDPTSSASLAANSLPGNHYWMDLINRQDALSAFLPIGPADFLVHHAIALGLHTTALILIKGALDARGTKLIPDKKDLGYAFPCDGPGRGGTCDSSSWDAMYLAMFWALNLLAWVTFYWHWKHLAIWQGNVAQFNESGTYLMGWFRDYLWLNSAQLINGYNPFGVNSLSPWAWMFLFGHLVWATGFMFLISWRGYWQELIETLVWAHQRTPIANLVGWRDKPVALSIVQARLVGLAHFTIGNILTFGAFVIASTSGKFG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: UBIA_VIBA3
Sequence: MLATKAKAYWQLTRMNRPIGTLLLLWPTLWSLIIAAKGMPDFDVLVVFILGVVLMRSAGCVINDFADRKVDGHVKRTKQRPLPSGLVSSKEAIVLFLVLAVVSFLLVLTMNPLTIKLSFIGVGLAFIYPFMKRFTHLPQLFLGLAFSWAIPMAWAAQTNELPSIVWFIFVINALWTIAYDTQYAMVDRDDDLKIGIKSTAILFGRFDKLMVGALQLVTLAMLIALGMHYQLGDTFYWALLVSGSLFVYQQHLMRHRDRDLCFQAFLNNNYVGMAVTVGLFITFW
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ELP3_METJA
Sequence: MVIIMDEKAKLMRCIIERILDEYNKGKTLDKKRIEQIKAECLRIHRIGIGHPSNSEILQYATEEEKKILIPILRKKPVRTISGVAVVAVMTSPEKCPHGKCIFCPGGVGSVFGDVPQSYTGREPATMRGLMFNFDPYLQTKARIEQLEKVGHPTNKIELIIMGGTFPARDIEYQDWFIKRCLDAMNGVDASSLEEAQKINETAEHRCVALCIETRPDYCGEKEINQMLKLGATRVELGVQTIYNEILEFCKRGHTVEDTIKATQLLKDSGLKVSYHLMPGMPGSDMEMDKKMFKEIFENPDFKPDMVKIYPCLVIEGTELYEMWKRGEYKPYREEEAIEIISYAKSIMPKWVRTSRIQRDIPATVIVDGVKKSNLGELVYKYMEKHGIKCKCIRCREVGHVMYKKGIMPDIEHIKLCREEYEASGGTEIFLSYEDVKNDILIAFLRLREPYKPFRKEIDDNTMLVRQLHVCGQEKPLTKDLKEITWQHKGYGRKLLEEAERIAKEEFGKKKILVTSGIGVREYYRKLGYERVGAYMGKYLE
What is the function of this protein?
tRNA uridine(34) acetyltransferase, which mediates formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.  The proposed mechanism is the following: (i) recruits S-adenosyl-L-methionine and cleaves it to generate a 5'-deoxyadenosine radical (5'-dA) in the radical S-adenosyl-L-methionine (rSAM) region, (ii) hydrolyzes acetyl-CoA in the N-acetyltransferase domain and (iii) an acetyl radical is formed by the products of the two domains and (iv) is transferred onto the C5 position of uridine(34) in the bound tRNA molecule.  Does not show protein lysine acetyltransferase activity.
What are the official names of this protein?
tRNA uridine(34) acetyltransferase, Elongator complex protein 3 homolog.
What is the protein family that this protein belongs to?
Belongs to the ELP3 family.
Protein: MKNK1_BOVIN
Sequence: MGSSEPIPIAESDKRKKKKRKARATDSLPGKFEDVYKLTSELLGEGANAKVQVAVSLQNGNEYAVKIIEKHAGHSRSRVFREVETLYQCQGNKHILELIEFFEDDTRFYLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFRHTKGIAHRDLKPENILCESPEKVSPVKICDFDLGSGVKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDEATFYDKRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCTVCQNKLFESIQKGKYEFPDKDWAHISNEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPERGLPTPQVLQRNSSTMDLTLFAAEAIALNRQLSQHEENEQNKLAEESEVLAEGLCSVKLSPPSKSRLARRRALAQAGRSGDAPPSPTPTTPAP
What is the function of this protein?
May play a role in the response to environmental stress and cytokines.  Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap (By similarity).
What are the official names of this protein?
MAP kinase-interacting serine/threonine-protein kinase 1, MAP kinase signal-integrating kinase 1, MAPK signal-integrating kinase 1, Mnk1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
Protein: CXD2_LEUER
Sequence: MGEWTILERLLEAAVQQHSTMIGRILLTVVVIFRILVVAIVGETVYDDEQTMFVCNTLQPGCNQACYDKAFPISHIRYWVFQIIMVCTPSLCFITYSVHQSSKQRERQYSTVFITLDKDKKREDNKIKNTTVNGVLQNSEFFTKEMQSDFLEVKEMQNSAARNSKMSKIRRQEGISRFYIIQVVFRNALEIGFLMGQYFLYGFKVPSMYECNRYPCVKMVECYVSRPTEKTVFLVFMFAVSGLCVILNLAELNHLGWRKIKTAVRGAQERRKSIYEIRNKDSPHRIGVPNFGRTQSSDSAYV
What is the function of this protein?
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
What are the official names of this protein?
Gap junction delta-2 protein, Connexin-35, Cx35, Gap junction alpha-9 protein.
What is the protein family that this protein belongs to?
Belongs to the connexin family. Delta-type subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Protein: RISB_VIBVU
Sequence: MKVIEGGFPAPNAKIAIVISRFNSFINESLLSGAIDTLKRHGQVSEDNITVVRCPGAVELPLVAQRVAKTGKFDAIVSLGSVIRGGTPHFDYVCSEMNKGLAQVSLEFSIPVAFGVLTVDTIDQAIERAGTKAGNKGAEAALSALEMINVLSEIDS
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: NRDR_STRZJ
Sequence: MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERVEERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENEIQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: HEX1_ARTBC
Sequence: MLWIWVPGILGLFGRVEALWPQPSEYSHGNKTLWLSPSVRFTYTNNQRSFIYTRPSYAGINWIPGGWLNLLQNPWGSAEQTVAEPLPNVEQFVEDAIKRTKHAIINSKFVPWKFHPRHQKFEPLVDGQHPTIEEVIINEASKTSQEWSPRNYVNGDEKYEIRISEDGEVQISSRSPIGTIRALQTFQQLFYSHSHSKSYTPFAPISISDSPKWRHRGLNLDISRNVIRPEDVKRTIDAMASVKLNRLHAHAADSQSWPLDIPSIPELAAKASYHPSQVWSSSELEAVQLYGLERGVSVFLEIDLPGHTAAVGHAFPDLVAAYHMDQWEKYAAEPPSGQIKLNSSAVYQFLDLLMADLIPRVSPLTEYFHTGGDEFNLNTYLLEINLGSNDRRVLTPFLDRMITHVHSSLRSSGVTPIVWEELVLDWDLNLPSHKTAGETGGVIVQAWRNSSAVKHVLQKGYQTIFGTGDAWYLDCGVGTFLNPRPGSKAVQNPYLDWCAPTKNWKHMYVYNPLKDIPVELQSLLVGGETHMWSELVDPVNMDQMIWPRAAAAAEVLWTGPRSPDNIQDASYRLAKWRERVVNDAGIRAAMVQMTYCLMRESGCEL
What is the function of this protein?
Beta-hexosaminidase that shows a broad substrate specificity (By similarity).
What are the official names of this protein?
Beta-hexosaminidase ARB_07893, Beta-GlcNAcase ARB_07893, Beta-N-acetylhexosaminidase ARB_07893, N-acetyl-beta-glucosaminidase ARB_07893.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 20 family.
What are the subcellular locations of this protein?
Secreted.
Protein: UREE_ALIB4
Sequence: MTFSVIKKVIEIKKDIPFSDEVELSWFDMQKPNLTAVTKKGVNLVVKAKFTHLHENDILVCEDGIGIKVKRSEDEIFSLEFSDALTFAKTAYEIGNRHQPLQIEEFKIIVLDDISIADIIKDCYANESIKVEKTKAYFKPNGKAHHSH
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSY3_YEAST
Sequence: MEVLKNIRIYPLSNFITSTKNYINLPNELRNLISEEQESKLGFLHIIESDFKPSVALQKLVNCTTGDEKILIIDIVSIWSQQKQRQHGAIYMNSLSCINITGLIVFLELLYDSPMDALRRCQVDNFNFQLRGIVIDNLSFLNFESDKNYDVINLSKFEKLFKILRKLREFLGCWIITKSFPTDFYNGIENTLVDKWSIKRKSGVTLYPTKLPDSYMKGMDLIIYREVVDGRPQYRRIAALEE
What is the function of this protein?
Required for resistance to the DNA-damaging agents methyl methanesulfonate (MMS), cisplatin and oxaliplatin, but not to mitomycin C.  Plays a role in protection against mutation accumulation.  May be a component of the recombination-repair pathway.
What are the official names of this protein?
Platinum sensitivity protein 3.
What are the subcellular locations of this protein?
Nucleus.
Protein: BRM1L_BOVIN
Sequence: MPVHSRGDKKETNHHDEMEVDYAENEGSSSEDEDTESSSVSEDGDSSEMDDEDCERRRMECLDEMSNLEKQFTDLKDQLYKERLSQVDAKLQEVIAGKAPEYLEPLATLQENMQIRTKVAGIYRELCLESVKNKYECEIQASRQHCESEKLLLYDTVQSELEEKIRRLEEDRHSIDITSELWNDELQSRKKRKDPFSPDKKKPVVVSGPYIVYMLQDLDILEDWTTIRKAMATLGPHRVKTEPPVKLEKHLHSARSEEGRLYYDGEWYIRGQTICIDKKDECPTSAVITTINHDEVWFKRPDGSKSKLYISQLQKGKYSIKHS
What is the function of this protein?
Involved in the histone deacetylase (HDAC1)-dependent transcriptional repression activity.  When overexpressed in lung cancer cell line that lacks p53/TP53 expression, inhibits cell growth (By similarity).
What are the official names of this protein?
Breast cancer metastasis-suppressor 1-like protein.
What is the protein family that this protein belongs to?
Belongs to the BRMS1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EFTS_LEIMA
Sequence: MLHRSLACFAVPADRKAFMELVKTLRYRTEAPISDCSAALKETDGDMDAAMQVLRKRGAARAMKKGDRVTEHGFVVSCVGSTPQSGAAIVTICSETDFAARNEHFQRVCMQVRDQLCKLMDATNGAVLANPEEAVKHLSDVMAEELRVAIAVLGENMRVRSIAPLVPAPHVSERLLIGSYTHGSLNVDNVGRIVGLVALSQVRENEVVPKDVLTSVGRHFVATSGAEGNYAHQNFFGSETETVGKWLKQRGLKFSSSLVQEFGKEPVVHTAPEPHR
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, mitochondrial, EF-Ts, EF-TsMt.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: DXR_BACSU
Sequence: MKNICLLGATGSIGEQTLDVLRAHQDQFQLVSMSFGRNIDKAVPMIEVFQPKFVSVGDLDTYHKLKQMSFSFECQIGLGEEGLIEAAVMEEVDIVVNALLGSVGLIPTLKAIEQKKTIALANKETLVTAGHIVKEHAKKYDVPLLPVDSEHSAIFQALQGEQAKNIERLIITASGGSFRDKTREELESVTVEDALKHPNWSMGAKITIDSATMMNKGLEVIEAHWLFDIPYEQIDVVLHKESIIHSMVEFHDKSVIAQLGTPDMRVPIQYALTYPDRLPLPDAKRLELWEIGSLHFEKADFDRFRCLQFAFESGKIGGTMPTVLNAANEVAVAAFLAGKIPFLAIEDCIEKALTRHQLLKKPSLADIQEVDKDTRGYVNSILT
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: SGSM3_RAT
Sequence: MSGNHTPSASGPFSALTPSIWPQEILAKSSQKEDSSEPEICYDEFGFRVDKEGSEPGCSQMAGTPLVEDPPQRLRWQAHLEFTHNHDVGDLTWDKIAVSLPRSEKLRSLVLAGIPHGMRPQLWMRLSGALQKKKNSELSYREIVKNSSNDETIAAKQIEKDLLRTMPSNACFANVNSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEEEDAFWMMCAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFLTAFASVVHIRLLLRIWDLFFYEGSLVLFQTTLGMLRLKEEELIQSENSASIFNTLSDIPAQMDDAELLLGEAMQLAGSLTDVAVETQRRKHLAYLIADQGQTLGTSTTTSLSQVVRRRTQRRKSGITSLLFGEDDLEALKAKNIKQTELVADLREAILRVARHFQCTDPKNCSVELTPDYSMESHQRDHENYVACLRSHRRRAKALLDFERHDDDELGFRKNDIITIISQKDEHCWVGELNGLRGWFPAKFVEVLDERSKEYSIAGDDSVTEGVTDLVRGTLCPALKALFEHGLKKPSLLGGACHPWLFIEEAAGREVERDFDSVYSRLVLCKTYRLDEDGKVLTPEELLYRAVQSVNVTHDAAHAQMDVKLRSLICVGLNEQVLHLWLEVLCSSLPTVEKWYQPWSFLRSPGWVQIKCELRVLCCFAFSLSQDWELPAKREEEKQPLKEGVQDMLVKHHLFSWDIDG
What is the function of this protein?
May play a cooperative role in NF2-mediated growth suppression of cells.  May act as a modulator of small G protein RAB- and RAP-mediated neuronal signal transduction and vesicular transportation pathways (By similarity).
What are the official names of this protein?
Small G protein signaling modulator 3, BDIF-1, RUN and TBC1 domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the small G protein signaling modulator family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KEFC_ECO5E
Sequence: MDSHTLVQALIYLGSAALIVPIAVRLGLGSVLGYLIAGCIIGPWGLRLVTDAESILHFAEIGVVLMLFIIGLELDPQRLWKLRAAVFGGGALQMVICGGLLGLFCMLLGLRWQVAELIGMTLALSSTAIAMQAMNERNLMVTQMGRSAFAVLLFQDIAAIPLVAMIPLLAASSASTTMGAFALSALKVAGALVLVVLLGRYVTRPALRFVARSGLREVFSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLFFIGVGMSIDFGTLIENPLRIVILLLGFLIIKIAMLWLIARPLQVPNKQRRWFAVLLGQGSEFAFVVFGAAQMANVLEPEWAKSLTLAVALSMAATPILLVILNRLEQSSTEEAREADEIDEEQPRVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQTNLQLTEMVKEHFPHLQIIARARDVDHYICLRQAGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRRFNIQMVEEMAMVENDTKARAAVYKRTSAMLSEIITEDREHLSLIQRHGWQGTEEGKHTGNMADEPETKPSS
What is the function of this protein?
Pore-forming subunit of a potassium efflux system that confers protection against electrophiles.  Catalyzes K(+)/H(+) antiport.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system protein KefC, K(+)/H(+) antiporter.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KCY_GEOSM
Sequence: MSVVRENGVIVAIDGPSGAGKSSLTKLLAKRLGYIHIDTGAMFRAVALSAQRAGIASDDDAGLAELCRGLDITFARDGEACRVLANGEDVSREIRTEEIGLLTSTVSARQPVRQALLEMQRKMGAKGGVILEGRDIGTVVFPDAEVKFFLSASAEERGRRRYLELAARGESATLEETIAKVVQRDRQDEGREHAPLKQAEDAVPIDSTSLTIEEVLELMERTVKERLAQGDKG
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YDC1_YEAST
Sequence: MLFSWPYPEAPIEGYWGKPTSLIDWCEENYVVSPYIAEWSNTITNSIFLMTAFYSTYSAWRNKLETRYILIGMGFSLVGIGSWLFHMTLQYRYQLLDELPMLYATIIPSWSIFAETQEILIKDEKKRKESSFRIQMVISFIMCGIVTILTWIYVVVQKPAIFQVLYGILTLLVVVLSGWLTYYHVHDSFAKKNLFITMVMGMIPFVIGFICWQLDIHLCSFWIYIRRTYLALPLGVLLELHAWWHLLTGTGVYIFVVYLQYLRILTHGNPNDFLFIWRWGFFPELVRKGLPIGTSYSLEYLGPIVNTQVDDETKKNN
What is the function of this protein?
Acyl-CoA-independent ceramide synthase that catalyzes the conversion of dihydroceramide and also phytoceramide to dihydrosphingosine or phytosphingosine.  Prefers dihydroceramide.  Very low reverse hydrolysis activity, catalyzing synthesis of dihydroceramide from fatty acid and dihydrosphingosine.  Is not responsible for the breakdown of unsaturated ceramide.  May play a role in heat stress response.
What are the official names of this protein?
Alkaline ceramidase YDC1, Acyl-CoA-independent ceramide synthase.
What is the protein family that this protein belongs to?
Belongs to the alkaline ceramidase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: C71BV_ARATH
Sequence: MTNIWLLSLIFVICILVAVFNHKNRRNYQRTPPSPPGCPIIGNLHQLGELPHQSLWKLSKKYGPVMLLKLGRVPTVIVSSSETAKQALKIHDLHCCSRPGFAGARELSYNYLDIAFSPYDDYWKEVRKLAVQELFSSKQVHSIQPIKDEEVKKLIDSISESAAQKTPINLNKTLLALTVSVVCRTAFSVNFEGTVLNSERFNNIVREALEMLGSFSASDFIPYVGRIIDLLTGLQGRRERSMRDLDAFYEQMFDLHKQKKEEGSEDFVDLLLRLEKEEAVLGNDKLTRNHIKAILMDVLLAGMDTSAITMTWAMAELAKNPRVMKKVQSEIRSQIKNKERISFDDTDKLEYLKMVIKETWRLHPTTPLLIPREAMSEFEINGYTIPVKTRLHVNVWAIGRDPDTWKDPEVFLPERFTDNNIDAKGQHFELLPFGGGRRMCPAVYMGTTMVEFGLANLLYHFDWKLPEGMKVDDIDMEEAPGLTVNKKNELILVPTKFLDP
What are the official names of this protein?
Cytochrome P450 71B34.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: FTHS_BACAA
Sequence: MTTTTTVKSDIEIAQEANMKKIQEIAADLNILEDELEPYGHYKGKLSLDIFKRLQNEKDGKVVLVTAINPTPAGEGKSTVTVGLGQAFNKIGKKTVIALREPSLGPTMGLKGGAAGGGFSQVVPMEDINLHFTGDIHAITTANNALAAFIDNHIQQGNTLGIDTRKIVWKRCVDLNDRALRNVVIGLGGPVQGVPREDGFDITVASEIMAVFCLATDIQDLKARLSRIVVAYNFANQPVTVKDLGVEGALTLLLKDALKPNLVQTLENTPAIIHGGPFANIAHGCNSVIATTMAAKLGDYVITEAGFGADLGAEKFLDIKARAAGIKPEAVVIVATIRALKMHGGVAKDQLKEENVDALAKGMENLQKHVETIQSFGVPFVIAINKFITDTDAEVAYLQEWCNERGYAVSLTEVWEKGGQGGVDLAEKVLKEIEKGENNYAPLYELELPLEEKIRTIAQKVYGAKDIEFAPKARKQLAQYEGEGWSNLPICMAKTQYSLSDDATKLGRPSDFIVTIRELKPSIGAGFIVALTGTMLTMPGLPKQPAALQMDVNEDGKAVGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: CH60_ENDTX
Sequence: MAKQLIYSDEARKAMKSGVDKLANAVKITLGPKGRYVVLDKKFGAPTITNDGVTIAKEIELEDPFENMGAQLVKEVASKTNDIAGDGTTTATVLAQSLINEGLKNITAGANANHIKKGIEKAVAAAIDEIKKIAKQVKNKGEIAQIASISASDKEIGNLIADAMEKVGKDGVITVEEGKSSETTLDVVEGMQFDRGYSSHYFVTDTERMQAILEDPYIIITDKKISSMQEILPLLEKIIQTGKSFMIIAEDIEGEALATLVLNKIRGTLKVIAVKAPGFGDRRKEMLQDIAILTGGTVITEETGLKLDKATIDLLGQAKRIVVDKENTTIVSGLGDKKEIEARIAQIRKQIEDTKSDYDKEKLQERLAKLVGGVAVVNVGAATEVEMKTKKFKVEDALNATRAGVEEGIVAGGGVALLKTQTVLEKINAADSDEKTGIEIVLKALEGPIRMIIENAGLEASVVVDKVKNSKDTAFGYDADNNEYVDMIKAGIVDPAKVTRTALENAASIASLILTTETLVTDIPEKSPKFPGGGGMPPMPEY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDH_ENT38
Sequence: MKKLIVLALVVSVAVAGGWLWMKSGNPDALRHIVLEQCLVNQQQHRNPAPCAQVKPDAGYVVFKDRNGPLQYLLMPTYRINGTESPLLTEPQTPNFFWLAWQSRNFMSMKRGTEVPDSAIALTINSPTGRTQNHFHIHISCLRPDVREKLDANQGQISTQWLPFPGGLEGHEYLARRVTEAELVKRSPFMMLAQELPQAREHMGRFAMAMAQQSDGSFVLLATERNLLVLNRASAEELQDHQCDILN
What are the official names of this protein?
CDP-diacylglycerol pyrophosphatase, CDP-diacylglycerol phosphatidylhydrolase, CDP-diglyceride hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Cdh family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.