PharMolix/UniProtQA huggingface dataset:
Protein: SYFM_YEAST
Sequence: MFLNRMMKTRTGLYRLYSTLKVPHVEINGIKYKTDPQTTNVTDSIIKLTDRSLHLKESHPVGILRDLIEKKLNSVDNTFKIFNNFKPVVTTMENFDSLGFPKDHPGRSKSDTYYINETHLLRTHTSAHELECFQKIRNDSDNIKSGFLISADVYRRDEIDKTHYPVFHQMEGATIWKRTKADVGVKEPMYIEKIREDIRQVENLLNKENVKITVDDDTIPLKENNPKQEYMSDLEVDLCSQHLKRSIELIVSEVFNKKISSMIKNKANNTPKELKVRWINAYFPWTAPSWEIEVWWQGEWLELCGCGLIRQDVLLRAGYKPSETIGWAFGLGLDRIAMLLFEIPDIRLLWSRDERFSRQFSKGLITSFKPYSKHPGSFRDVAFWLPEDKPDIHQVHENDLMEIIRNIAGDLVESVKLVDSFTHPKTGRKSMCYRINYQSMDRNLTNAEVNTLQDMVCSKLVKEYSVELR
What is the function of this protein?
Is responsible for the charging of tRNA(Phe) with phenylalanine in mitochondrial translation.
What are the official names of this protein?
Phenylalanine--tRNA ligase, mitochondrial, Phenylalanyl-tRNA synthetase, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: VSP2_TRIAB
Sequence: MMLIRVLANLLILQLSYAQKSSELVIGGDECNINEHRFLVALYDVWSGDFLCGGTLINKEYVLTAAHCETRNMYIYLGMHNKMYQFDDEQRRYPKKKYFFRCSNNFTRWDKDIMLIRLNRPVRNSEHIAPLSLPSSPPSVGSVCRVMGWGTITSPNETLPDVPRCANINLLNYTVCRGVFPRLPARSRTLCAGVLQGGIDTCKRDSGGPLICNGKLQGVVFWGPKPCAQPRKPALYTKVFDHLDWIQSIIAGNTTVTCPP
What is the function of this protein?
Thrombin-like snake venom serine protease.
What are the official names of this protein?
Thrombin-like enzyme 2, SVTLE, Fibrinogen-clotting enzyme, Green pit viper thrombin-like enzyme 2, GPV-TL2, Snake venom serine protease, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CLPS_SHESA
Sequence: MGKTGNIEHVEERVESELMPPSMYKVILNNDDYTPMDFVIEVLQIFFRKNEQEATDIMLTIHHQGKGICGIFPYGIAETKVIQVNQFARQNQHPLLCSLEKA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: UBXN1_DANRE
Sequence: MADCTTLDSLLEMGFGRNRAEKAVAHTGNQGIERAMDWLMEHENDPDIDEPYVPPAGNTLGPAEEQSQSPTEIPESIEDTEEGNARQPMTEEERKEQVKRLEDLMKARQEERRERERQEGIEREKQRRKQGQELLQVRQKLQEDEMKKLADQRRKEKMEDRLAKQRVKDKIARDREERAQKFGGGSSSTGLSSPPAEAPALSPPENQGAPPAKKDYDDCRIQVRLLDGTTLSTVFKAQEPLAAVRVYVQMNGANGQDFNLITPYPRRVYTDLDMEKPLRELGLVPSAVLVVTKK
What is the function of this protein?
Ubiquitin-binding protein that specifically binds 'Lys-6'-linked polyubiquitin chains.  Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol.  Involved in ubiquitin-proteasome systems (By similarity).
What are the official names of this protein?
UBX domain-containing protein 1, SAPK substrate protein 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_ECO8A
Sequence: MKNIRNFSIIAHIDHGKSTLSDRIIQICGGLSDREMEAQVLDSMDLERERGITIKAQSVTLDYKASDGETYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAGQGVEAQTLANCYTAMEMDLEVVPVLNKIDLPAADPERVAEEIEDIVGIDATEAVRCSAKTGVGVQDVLERLVRDIPPPEGDPEGPLQALIIDSWFDNYLGVVSLIRIKNGTLRKGDKVKVMSTGQTYNADRLGIFTPKQVDRTELKCGEVGWLVCAIKDIHGAPVGDTLTLARNPAEKALPGFKKVKPQVYAGLFPVSSDDYEAFRDALGKLSLNDASLFYEPESSSALGFGFRCGFLGLLHMEIIQERLEREYDLDLITTAPTVVYEVETTSREVIYVDSPSKLPAVNNIYELREPIAECHMLLPQAYLGNVITLCVEKRGVQTNMVYHGNQVALTYEIPMAEVVLDFFDRLKSTSRGYASLDYNFKRFQASDMVRVDVLINGERVDALALITHRDNSQNRGRELVEKMKDLIPRQQFDIAIQAAIGTHIIARSTVKQLRKNVLAKCYGGDISRKKKLLQKQKEGKKRMKQIGNVELPQEAFLAILHVGKDNK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: BIOC_PRIM3
Sequence: MINKQLLKKRFNNHAKTYDAYADVQKSMAHQLINQLSTNFFNQEIAILEIGCGTGYLTQLLCKKFPKAAITAVDLSSGMIELAKKKVTEDRVSLICGDIEELSIERQYDLIISNATFQWFNSLHTTIKKLYKQLKPAGSLLFSTFGNGTFQELHSCYSHAKQKLGLFSNSSPGQSFFSLEELSQICEQALVPLREHPFKLSKMEKLEVQYFPTVQAFFTSIKKIGASNSNEESYCQRPSFFRQLINLYENNHRDENGVKVTYHCLMFNITKTNQ
What is the function of this protein?
Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM).  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.
What are the official names of this protein?
Malonyl-[acyl-carrier protein] O-methyltransferase, Malonyl-ACP O-methyltransferase, Biotin synthesis protein BioC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: PACA_BPP1
Sequence: MTWDDHKKNFARLARDGGYTIAQYAAEFNLNPNTARRYLRAFKEDTRTTDSRKPNKPVRKPLKSMIIDHSNDQHAGDHIAAEIAEKERVNAVVSAAVENAKRQNKRINDRSDDHDVITRAHRTLRDRLERDTLDDDGERFEFEVGDYLIDNVEARKAARAMLRRSGADVLETTLLEKSLSHLLMLENARDTCIRLVQEMRDQQKDDDEGTPPEYRIASMLNSCSAQISSLINTIYSIRNNYRKESREAEKHALSMGQAGIVKLAYERKRENNWSVLEAAEFIEAHGGKVPPLMLEQIKADLRAPKTNTDDEENQTASGAPSLEDLDKIARERAASRRADAALWIEHRREEIADIVDTGGYGDVDAEGISNEAWLEQDLDEDEEEDEEVTRKLYGDDD
What is the function of this protein?
Necessary for recognition and cleavage of the phage packaging site (pac), together with the pacB protein.  Both are probably the two major subunits of the phage PACase.
What are the official names of this protein?
Terminase A protein, DNA-packaging protein A, PACase A protein.
Protein: RHLB_SHEB9
Sequence: MSETHLSTQRFADLPLHPEVKQALAENGFEFCTPIQALSLPVLLQSKDIAGQAQTGTGKTMAFLVATFNHLLSTPVPEGRLINQPRAIIMAPTRELAIQIAKDAILLAKHTHLKVGIVYGGESYDVQRKVLDQGVDILIGTTGRIIDYVRQGIIGLNSIQAVVLDEADRMFDLGFIKDIRFLFRRMPEANQRLNMLFSATLSMKVQELAYDHMNEPVKVEIAPEEKTSKNIKEEIFYPSQEEKMRLLLTLIEEDWPEKAIVFSNTKHSCETLWSWLEGDGHRVGLLTGDVPQKKRIRILEQFTSGQLDILVATDVAARGLHISDVSHVYNYDLPDDCEDYVHRIGRTGRAGNKGMSISFACEEYALNLPAIESYINHSIPVSNYDSEALLADIPTPAKIHRKHPSGTRNLRDRSGASRPGAQRSGARPPRHDRTRRHS
What is the function of this protein?
DEAD-box RNA helicase involved in RNA degradation.  Has RNA-dependent ATPase activity and unwinds double-stranded RNA.
What are the official names of this protein?
ATP-dependent RNA helicase RhlB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. RhlB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCD_SALEP
Sequence: MSWIERIKSNITPTRKASIPEGVWTKCDSCGQVLYRAELERNLEVCPKCDHHMRMSARNRLHSLLDEGSLVELGSELEPKDVLKFRDSKKYKDRLASAQKETGEKDALVVMKGTLHGMPVVAAAFEFAFMGGSMGSVVGARFVRAVEQALEDNCPLVCFSASGGARMQEALMSLMQMAKTSAALAKMQERGLPYISVLTDPTMGGVSASFAMLGDLNIAEPKALIGFAGPRVIEQTVREKLPPGFQRSEFLIEKGAIDMIVRRPEMRLKLASILAKLMNLPAPNPDAPREGVVVPPAPDQESEA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_SALDC
Sequence: MIQEQTMLNVADNSGARRVMCIKVLGGSHRRYAGVGDIIKITIKEAIPRGKVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVILNNNSEQPIGTRIFGPVTRELRNEKFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: MAO1_ALISL
Sequence: MNNHIRPLYIPYAGPALLSTPLLNKGSAFSTTERKYFNLEGLLPEAIESIEEQTGRAYKQYQSFENDMDKHIYLRNIQDTNETLFYRLVQNHISEMMPIIYTPTVGAACENFSNIYRRGRGLFISYENKNRIDDLLNNAANQNVKVIVVTDGERILGLGDQGIGGMGIPIGKLALYTACGGISPAHTLPIVLDVGTNNPQRLADPMYMGWRHPRVTGNEYKDFVEEFIQAVQRRWPQALVQFEDFAQKNAMPLLERYKNRICCFNDDIQGTAAVTVGSLLAACKAAGSSLAQQRVTFLGAGSAGCGIAEAIIAQMVSEGISDAQARSQVYMVDRWGLLQEGMPNLLDFQQRLVQKAENTKEWVSEEPNYSLFDVMHNAKPTVLIGVSGAPGLFSKEVIQEMHKHCERPIVFPLSNPTSRVEATPNDIIRWTDGQALVATGSPFDPVTHNGQTYPIAQCNNSFIFPGIGLGVLAIKATRVSDEMLRESSRALSECSPLAINGSGALLPPLEEIHTVSKKIAFAVAKKAIEQGYALEITDEALMQKIEQYFWKPVYRRYKRTAF
What are the official names of this protein?
NAD-dependent malic enzyme, NAD-ME.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
Protein: ARNB_SALEP
Sequence: MSDFLPFSRPAMGAEELAAVKTVLDSGWITTGPKNQELEAAFCRLTGNQYAVAVSSATAGMHIALMALGIGEGDEVITPSMTWVSTLNMIVLLGATPVMVDVDRDTLMVTPEHIEAAITPQTKAIIPVHYAGAPADLDAIYALGERYGIPVIEDAAHATGTSYKGRHIGARGTAIFSFHAIKNITCAEGGIVVTDNPQFADKLRSLKFHGLGVDAWDRQSGGRAPQAEVLAPGYKYNLPDLNAAIALAQLQKLDALNARRAAIAAQYHQAMADLPFQPLSLPSWEHIHAWHLFIIRVDEARCGITRDALMASLKTKGIGTGLHFRAAHTQKYYRERFPTLTLPDTEWNSERICSLPLFPDMTESDFDRVITALHQIAGQ
What is the function of this protein?
Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase, UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase, UDP-Ara4O aminotransferase, UDP-4-amino-4-deoxy-L-arabinose aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.
Protein: RS21_AKKM8
Sequence: MREVTVRKGEPIDRALKRLKTKLDVEGILDEMRRRRAFETPMDERRRKARSASKRNKVKWRYSNKSEETASETAETPASAPEA
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: IL4_BUBCA
Sequence: MGLTYQLIPVLVCLLVCTSHFVHGHKCDITLAEIIKTLNILTTRKNSCMELPVADVFAAPKNTTEKETFCRVGIELRRIYRSHTCLNKFLGGLDRNLNSLASKTCSVNEAKTSTSTLKDLLERLKTIMKEKYSKC
What is the function of this protein?
Participates in at least several B-cell activation processes as well as of other cell types.  It is a costimulator of DNA-synthesis.  It induces the expression of class II MHC molecules on resting B-cells.  It enhances both secretion and cell surface expression of IgE and IgG1.  It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.  Positively regulates IL31RA expression in macrophages.  Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4.
What are the official names of this protein?
Interleukin-4, IL-4, B-cell stimulatory factor 1, BSF-1, Lymphocyte stimulatory factor 1.
What is the protein family that this protein belongs to?
Belongs to the IL-4/IL-13 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATP61_PELPD
Sequence: MVHPLLFLEFFRKLLEPLHMSEAGADAVAYTWLIMLLLLLFSFLATRALKMIPCGLQNFMEVVVGGVENMIVETMGEHGRPYFPLVATVGLFVLVSNLIGLIPGFFPPTANINTTAACAIVVFIATHVVGIKRHGIGYIKHFCGPILWLAPVMFFIEVIGHLSRPLSLTLRLFGNMNGHELVLIIFFGLAPFLVPLPMMLMGVLVSFIQAFVFMLLTMIYIQGSLEEAH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a 1, ATP synthase F0 sector subunit a 1, F-ATPase subunit 6 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: P5CS_MESCR
Sequence: MDATRAFVKDVKRVVVKVGTAVVTRSDGRLALGRLGSLCEQLKELNSDGYEVILVTSGAVSAGRQRLRFRKLVNSSFADLQKPQVELDGKACAAVGQNGLMALYDTLFSQLDLTAAQLLVTDNDFRDPSFRTQLTETVYQLLDLKVVPVLNENDAVSTRKAPYEDSSGIFWDNDSLAALLALELKADLLILLSDVDGLYNGPPSDPRSKLISTYVKEKHQGEITFGDKSRLGRGGMTAKVKAAVYAAYAGIPVIIASGKATDNIIKVIDGQCVGTLFHKDAHLWVQVKETGVRDMAVAARESSRRLQAVSSEERKKILLDIADALEANEEKILAENEADVAAAQYAGYDRSLVARLAMNPDKISSLAKSIRVLADMEEPIGRILKRTEIADGLILEKTSCPLGVLLIVFESRPDALVQIASLAIRSGNGLLLKGGKEAKRSNAILHKVITSAIPDKVGEKLIGLVTSRDEIPDLLKLDDVIDLVIPRGSNKLVSQIKESTRIPVLGHADGICHVYVDKSANMDMAKRIVLDAKTDYPAACNAMETLLVHKDLAENGGLNDLIVDLRTEGVTMFGGPRIDALQEFNIQATQTFNREYSSPACTVEIVDDVYAAIEHINHHGSAHTDCIIAEDHKVAETFLQLVDSAAVLHNASTRFCDGFRFGLGAEVGISTSRIHARGPVGVEGLLTTRWVLKGSGQVVHGDKGVVYTHKDLPLVAQNS
What is the function of this protein?
P5CS plays a key role in proline biosynthesis, leading to osmoregulation in plants.
What are the official names of this protein?
Delta-1-pyrroline-5-carboxylate synthase, P5CS.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
Protein: LRC61_MOUSE
Sequence: MEPPGEKPGEAEALSITPQLLKSHSGEFALDSILLLKLRGLGVVDLGCLGECLNLEWLDLSGNALTHLGPLASLRQLAVLNVSNNRLTGLEPLAACENLQSLNAAGNLLTTPGQLQCLAGLQALEHLRLRDPLARLSNPLCANASYWAVVRELLPGLKVIDGERVSGRGSELYQLCRDLDSSLRSGSSPGPRAIEAQPWVEPGYWESWPIRSSSILEEACRQFQDTLQECLDLDRQASDSLAQAQQALSPAETTSSFVF
What are the official names of this protein?
Leucine-rich repeat-containing protein 61.
Protein: MURD_STRPN
Sequence: MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFEDNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTEVELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASDKDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAADFLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPGSHNVENALATIAVAKLRDVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNILATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKAGVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_FRATH
Sequence: MDINITLIGQMITFAIFIGFTMKFVWPPLRKALEERREKIAEGLASADRASRELEVAKRQSAEILREAKAKATEIVENAYVRAHKVDEQAKEEAIAAADKIKSMAIAEIEQEKVKAKEQLKQELVNLAMAAASKIIAASVDEKASKKVLEDFVEKV
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: YU0O_CAEEL
Sequence: MKLKKRPMKLAAKPKPKQPTEKLGKAQKMKLKEDNLASAEKIMAQFESGAVHTNKKKQAQNGAAKPVAHKPANPENSNQKRQFKKILGQDGILVKHQEGTKWYSYQIDHVHDEKTEKMNASEIQKLLEEGKDEMAQDAALLQTKEKQDNGSEASWLYSVISKGTATDKRTAMQLQMHKSPVHSLEYIEKLIASCKKQGTRDVVDIIPILEDVFINHCLPENRKLIPFSKRALRELTELSSGNQRLRRKILLMWAFEHELKILYQQFIETLVEIIKRPLEEVIKRSLKTLANCLMGRPESENLILSALVNAFGHPNYKIGAFTVVLLEGISRKHPAMRIVMVEEIERLAFRKNVNERAHLYAMTFLSQMKFSKKDSDLCCRLMSIYLSLFKTIVGKKITDNRLLPIILAGANRAFPFAKDADKLLEDVKDVYFLAHNSNYRTAIPALKLLFQFHKMNDYVSDRFYNALYRKLLDNCPAGAYAQLLKLMFDTMKEDSSAQRVRTFVKRLLQVAVNSQPDFTASILILISRLQKLRGTTEKLVVLSKDIDPAARVVAQMQNDEDDEERYVDLDVEGNEISRNGVKKEEKEEEDIVIEENEDEDKKKVQPGKLGASSSGGWVHRSIGARGAKTPYDSVARNPLFVDASHTADSELLLLSKHYHPSVAVFAKALMEGREINYGGEALNDFTLMAFLDRFAFRNPKDVTKTTGTRIVRKKAHDPWGVRKLAVGSNEYTQKRREEIPADERFLHRYTSSLQKEKKVKKENGDDDWEYAESVSSAEFDQLLERFEPGELNEEFDIDYSKEFGAEKSKRNKKKDVEEDDVDMDEDDDIDLNDLNEEEDGGMEDDDEDDGDMDDDDEDDEDAEDDDEVDDDDEDDDEDGGFGGKSSANIFGDADESSDEEIGANDYEMAGDKFAEMLEDLEEDDGKRGKKKGGKKRGSTGGFKRGGAKKFRKR
What are the official names of this protein?
Uncharacterized protein F23B12.7.
What is the protein family that this protein belongs to?
Belongs to the CBF/MAK21 family.
Protein: C2AIL_RAT
Sequence: MVGGEATSAVEKLVSGVRQAADFAEQFRSYSESEKQWKARMEFILRHLPDYRDPPDGGGRLDQLLSLSMVWANHLFLGCSYNKDLLDKVMEMADGIEVEDLPQFTSRSELMKKHQS
What are the official names of this protein?
CDKN2AIP N-terminal-like protein, CDKN2A-interacting protein N-terminal-like protein.
What is the protein family that this protein belongs to?
Belongs to the CARF family.
Protein: Y1553_METJA
Sequence: MKFLFSKTKIEILKKLNERNYTISELSKILGKSKSTISEHLNALYEMGLVDKENYSKWVYYKITNKGKKVLENLEALILMVSSIFALIGLWIYYIFKQIKYQAREVVLSKTVVERGIYTTYKGSTTFQKEPLFLIFLIISTFLIIFIVYLVYKIIRR
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator MJ1553.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AMPH_CHICK
Sequence: MADMKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGSRLQRELRAYLAAIKGMQDASKKLTESLHEVYEPDWYGREDVKMIGEKCDELWEDFHQKLVDGSLLTLDTYLGQFPDIKTRIAKRSRKLVDYDSARHHLEALQSSKRKDEGRITKAEEEFQKAQKVFEEFNTDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIALLCHKLYEVMTKLGDQHADKAFTIQGAPSDSGPLRIAKTPSPPEEVSPLPSPTASPNHMLAPASPAPARPKSPTQLRKGPPVPPLPKLTPTKELQQENIINLFDDNFVPEINVTTPSQNEIPETKKVESLLDLDFDPFKPEVVSTGVTHSPMSQTLPWDLWTTTSELVQPASSTAFNGFAQDTTAFAVQSNENVTETLTEAEEAPLGELKVEETPTAAVVEKEAILAEPDEPTEQAAESIEAGDKETTGIAEKESEVVSAAGGAVAVEDSVVVAAGAGEGAVRTEQEAAAEGDKPQGEEKDVDVSQEKVSSIPSVVIEPASNNEGEGEEHHVIMNESKDAAAEMGTQGTDSETSQIGSEQKATEEIQTTPSQDQPASAGDTASDMPPGFLFKVEVLHDFEAANSDELNLKRGDIVLVIPSETTADQEAGWLTGIKESEWLQYRDANSYKGLFPENFTRHLE
What is the function of this protein?
May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types.  May control the properties of the membrane associated cytoskeleton.
What are the official names of this protein?
Amphiphysin.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton.
Protein: VRK3_BOVIN
Sequence: MICPDCGKGIEATFKFCPYCGKPLPAEKHEGSQSFVKPFTSSSQGSRRKTNTSSETSSKKVKWCSYAASPSLPLPSEGKSSGSEDTLSTSGKPKGHLSRSPTPRSSPQTTRQSPQTLKRSRMTASLEALPVGTVLTDKSGQHWKLRCLQTRDDQGILYEAESDSTTGSESSPQKQRFSLKLDAKDGRLFNEQNFFQRAAKPLQVNKWKKLYSIPQLAIPTCIGFGVHQDKYRFLVFPTLGRSLQSILDDFPKHVMSVRSVFQMACRLLDALEFLHENEYVHGNVTAENIFVNPENLCQVTLAGYGFTFRYSPGGRHVAYTEGSRSPHEGHLEFISMDLHKGCGPSRRSDLQTLGYCLLKWLYGTLPWTNCLPNTEEIVKLKQKFLDNPEGLVGQCSRWITPSETLQEYLKVVMALQYEEKPPYSTLRNELEALLQDLRASAYDPLDLQVVP
What is the function of this protein?
Inactive kinase that suppresses ERK activity by promoting phosphatase activity of DUSP3 which specifically dephosphorylates and inactivates ERK in the nucleus.
What are the official names of this protein?
Inactive serine/threonine-protein kinase VRK3, Serine/threonine-protein pseudokinase VRK3, Vaccinia-related kinase 3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. VRK subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: R23A1_CAEEL
Sequence: MAPSAPAKTAKALDAKKKVVKGKRTTHRRQVRTSVHFRRPVTLKTARQARFPRKSAPKTSKMDHFRIIQHPLTTESAMKKIEEHNTLVFIVSNDANKYQIKDAVHKLYNVQALKVNTLITPLQQKKAYVRLTADYDALDVANKIGVI
What is the function of this protein?
This protein binds to a specific region on the 26S rRNA.
What are the official names of this protein?
60S ribosomal protein L23a 1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: NUCK_BPT7
Sequence: MGLLDGEAWEKENPPVQATGCIACLEKDDRYPHTCNKGANDMTEREQEMIIKLIDNNEGRPDDLNGCGILCSNVPCHLCPANNDQKITLGEIRAMDPRKPHLNKPEVTPTDDQPSAETIEGVTKPSHYMLFDDIEAIEVIARSMTVEQFKGYCFGNILKYRLRAGKKSELAYLEKDLAKADFYKELFEKHKDKCYA
What is the function of this protein?
Nucleotide kinase that catalyzes the phosphorylation of dGMP and dTMP to dGDP and dTDP (PubMed:18599435, PubMed:20497505).  A double mutation in this protein and the RecBCD inhibitor gp5. 9 protein allow phage to overcome the retron Ec48 bacteriophage defense system.  This protein alone when overexpressed in E. coli does not cause growth arrest; Y128C may be a silent mutation (PubMed:33157039).
What are the official names of this protein?
Nucleotide kinase gp1.7, Gene product 1.7, Gp1.7.
Protein: Y461_CERS1
Sequence: MSGEVSYYAGQTAEEAVARIYDRSGRPVAARRWRGVSGEIDLIAREGAEVIFIEVKKSKSHAAAAARLSRRQMDRIYGAASEFLAGEPRGQLTASRFDVALVDALGRVEIIENAFAA
What are the official names of this protein?
UPF0102 protein Rsph17029_0461.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: THIE_BACHK
Sequence: MSRISKAEMSKLLSVYFIMGSNNCTKDPLQVLREALEGGITIFQFREKGEGALTGEERICFAKELQAICKEYGVPFIVNDDVELALELDADGVHVGQDDEGITSVREKMGDKIVGVSTHTIEEARWAIENGADYLGVGPIFPTSTKKDTKAVQGTKGLAHFREQGITIPIVGIGGISIENTALVIEAGADGVSVISAISLAESAYESTKKLVEEVSRSL
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: GCL_DROME
Sequence: MGQIVGSMHMNVAEVFSNRRKRKRSTDSSLGKDDPAQLDTTQPKKKKLLTTTQYIYKALFKEEKNSDVAVMALDKVWHLHKVYLSQSPYFYTMFNGTWREAQQNFIQITILDDRITVASLDAVFGSMYSDEIEIESADVISVLATATLFHLDGIIDKCAEVMVDNISPETAIQYYEAACQYGVVGVKKSTFQWFQINLLSIYSKQPNLLRHISIELMSALTASPDLYVMQTEFSLYTLLRTWMFLRLHPDYDPEDPVQRAEALKTQELLVNAGVETHAPSGDVVQWTYFTSRSEERSFLATPEGQPYVKVFQKLRTQYLTNHYMDLKIIYNDNIIPKEWLYRHIHNHWDALLRIDHGQEDCSPQQLDDEQFFENCMRCGRMLLEPGYQKWRWTGFNFGMDLILIMDSRRLNIRRHHRHEHERVLSLQTKRKFMVRTTVTSINAQRQAVFTQTSEICSLSLEKNEEVPLMVLDPKLVHPLLISINMLVVMPPNQSFKEIVPLSEEATTSLSIPISEIGANSDRPLSPSSADDSAVFIGDSEPSTPSSPAPRPRIAWSASETGAICGQLAC
What is the function of this protein?
Required for the specification of pole cells and germ cell formation.  Mothers with reduced glc function give rise to sterile adult progeny that lack germ cells.
What are the official names of this protein?
Protein germ cell-less.
What are the subcellular locations of this protein?
Cytoplasm. Note=Pole plasm.
Protein: RL5_ALKMQ
Sequence: MARIKDKYRNEVAPAMMEKFGYKSVMQIPRLEKIIINMGLGQAKENQKELEIAVKELGIIAGQKPITTKAKKSVANFKVREGMAVGAKTTLRGEKMYEFADRLINIALPRVRDFRGVNPNSFDGRGNYALGVKEQLIFPEIEYDKVDKVRGMDIILVTTANSDEESRELLRLLGMPFTK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.