PharMolix/UniProtQA huggingface dataset:
Protein: CYT_NAJAT
Sequence: IPGGLSPRSVSDPDVQKAAAFAVQEYNAGSANAHYYKELRVVEAQSQSVAGEKYFLMMELVKTKCAKTAGKPKVYKEIQNCELPPIKQQEEKLCGFQVW
What is the function of this protein?
Inhibits various C1 cysteine proteases including cathepsin L (Ki is 0. 1 nM), papain (Ki is 0. 19 nM), cathepsin S (Ki is 1. 2 nM), and cathepsin B (Ki is 2. 5 nM).  This protein has no toxic activity and its function in the venom is unknown.  It may play a role as housekeeping or regulatory protein.
What are the official names of this protein?
Cystatin.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS4_SHIDS
Sequence: MMIIPALDLIDGTVVRLHQGDYGKQRDYGNDPLPRLQDYAAQGAEVLHLVDLTGAKDPAKRQIPLIKTLVAGVNVPVQVGGGVRSEEDVAALLEAGVARVVVGSTAVKSPEMVKGWFERFGADALVLALDVRIDEQGNKQVAVSGWQENSGVSLEQLVETYLPVGLKHVLCTDISRDGTLAGSNVSLYEEVCARYPQVAFQSSGGIGDINDVAALRGTGVRGVIVGRALLEGKFTVKEAIACWQNA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_CLOB6
Sequence: MNISIISVGKIKEKFLKAAIDEYSKRLSKYCKLNIIEVPDEKTPDNASLKEENIIKEKEGTLILKHIKDNSFVIALDLKGKSIASEEFSDLIENCRLTGNSTIAFVIGGSLGLSEQVLSRANYRLSFSKMTFPHQLFRVMLLEQVYRAFRILCREPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NSP5_ROTH5
Sequence: MSLSIDVTSLPSISSSVYKNESSSTTSTISGKSIGRSEQYISPDAEAFNKYMLSKSPEDIGPSDSASNDPLTSFSIRSNAVKTNADAGVSMDSSAQSRPSSDIGYDQMDFSLNKGIKIDATVDSSISISTTSQKEKSKQENKNKYKKCYPKIEAESDSDDYILDDSDSDDGKCKNCKYKKKYFALRLRMKQVAMQLIKDL
What is the function of this protein?
Plays an essential role in the viral genome replication.  Participates, together with NSP2, in the formation of viral factories (viroplasms) which are large inclusions in the host cytoplasm where replication intermediates are assembled and viral RNA replication takes place.  Orchestrates the recruitment of viroplasmic proteins such as capsid proteins to these factories.
What are the official names of this protein?
Non-structural protein 5, NSP5, NS26.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP5 family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: HXB1_AMBME
Sequence: GTPTTACSLPGGGGGWLWGGTCVQAMGRGGHRPSDGHLSPSPCCAFFSRCLCCFFGLYALSTSLALISSLFSLLTAKLSEYGLGSQQNSIRTNFTTKQLSELEKEFHFNKYLTRARRVEIAATLELNETQVKIWFQNRRMKQKKREKEGLAPSNGPQGRAREASEASDQSSSPSPYASPDSFSS
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.  Acts on the anterior body structures (By similarity).
What are the official names of this protein?
Homeobox protein Hox-B1, AHox1.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family. Labial subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYOE_TERTT
Sequence: MALIIRSEIDKATQAITTALPWRDYYELTKPKVVMLMLLTSLIGMLLATPSPAPLWLLVLGNLGIGLCAGAAAAVNHLVDRHVDVKMARTFHRPVANGRITPTNALLFSALLGGVGLWILSSFINALTAWLTLASLLGYAVIYTLFLKRATPQNIVIGGLAGAAPPLLGWTAVTGELDGHGLLLVLIIFAWTPPHFWALALYRKKEYAKAGIPMLPVTHGDSYTRLHIVLYTVILIAVTLLPFATRMMGYCYLVGALVLGAGFLYRALKLLVSKDPKQGLETFKFSIIYLMALFVVMLVDHYLFPIPVYGV
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PROB_RHOPT
Sequence: MASPKLHDFRHIVVKVGSSLLIDSAAGEVRAGWLAALAADIAELHRGGRDVMVVSSGSIALGRSRLKLPRGPLKLEESQAAAAVGQIELARTWSEVLGAHGIGAGQILVTFQDTEERRRYLNARSTIAKLLEWRAVPVINENDTVATTEIRYGDNDRLAARVATMASADLLILLSDIDGLYTAPPGNDPDATLIPVVEAITAEIEGMAGAAGSELSRGGMRTKIEAAKIATSAGTHMLIASGKIDHPLRAIAEGGKCTWFLTPANPVTARKRWIAGTLEPKGTLTIDAGAVSALRAGKSLLPAGVIRVDGQFSRGDAVIVRGPDTHEIGRGLVAYDAEDAEKIKGHSSPDVMMILGITGRAEMIHRDDLVVGTAPT
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_RHILO
Sequence: MFNQHKVEIEWGGRPLILETGKIARQADGAVLATYGETKVLATVVSMKEPKPGLDFFPLTVNYQEKTYAAGKIPGGYFKREGRPSEKETLVSRLIDRPIRPLFADGYKNDTQIVVTVVQHDLENDPDILSIVATSAALTLSGVPFMGPVGGARVGYINGEYVLNPHIDEMQESKLDLVVAGTADAVLMVESEAKELGEELMLGAVMFGHKGFQPVIDAIIKLAEVAAKEPRDFTAPDYSALEGEMLKIVGDELSNAYKITDKQQRYAAVDAVKAKVKAAFAPAEGEEPKYTSEQIGSVFKELQAKVVRWNILDTGSRIDGRDLKTVRKIVSEVGVLPRTHGSALFTRGETQALVVATLGTGEDEQYVDSLTGMYKEKFLLHYNFPPYSVGETGRMGSPGRREIGHGKLAWRAIRPMLPSADQFPYTLRVVSEITESNGSSSMATVCGTSLALMDAGVPLAKPVAGIAMGLIKEGERFAVLSDILGDEDHLGDMDFKVAGTANGITSLQMDIKIEGITEEIMKIALDQAKDGRQHILGEMAHALTGARPELGEFAPRIEVMHIPTDKIRDVIGSGGKVIREIVEKTGAKINIEDDGTVKIASSNAKEIEAAKKWIHTIVAEPEVGEIYEGTVVKTADFGAFVNFFGPRDGLVHISQLANERVAKTSDVVKEGDKVWVKLMGFDERGKVRLSMKVVDQATGKEIVRDKRAEGEEDAA
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRG7_ZYGRC
Sequence: MSRLKAINGIMLRPIIWKRPSSNDAILQFIRQNQEISQSSVFQGTLYEHTVMRELSGKLSMNQLQKIGGSHDRGVDIRGQWPLDFVFGQVTKVVPLDAVPKRCKIHGTTLKPLRCKIEENDGKLDPLKALVQCKAFSGSKVSPREFRELVGTFASIVPDSQRNRSVILMCSPNLLTKEGLSLINTVKVPLIYLRIEMLQRIGDNYDVDNSGRLLNYYENDYAAALLQGCGIKEWLKLSLYRR
What are the official names of this protein?
Required for respiratory growth protein 7, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RRG7 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CDK15_DANRE
Sequence: MQNLRHAASEAFQRLGLKQRHLGYEELGELDGVEKPQPHWFHTLQVRRLRVQRGRSNSDPMGGKSFQQEFQWKTGLQFGNATSYLNLEKLGEGTYATVYKGISRINGHLVALKVIHMKTEEGIPFTAIREASLLKGLKHANIVLLHDIIHTRESLTFVFEYVQTDLAQYMIQHPGGLHSYNIRLFMFQLLRGLSYIHGRRILHRDLKPQNLLISYLGELKLADFGLARSKSIPCQTYSAEVVTLWYRPPDVLMGSTDYSTALDIWGAGCIFIEMLQGSPAFPGVADVFEQLLKIWTVIGVPTEEIWPGVSDLPNYKPEWFLPCKPQQFRDVWKRLSQLPYKTEDLAQQMLMMNPKDRISAQDALLHPYFNTLPPPLMHLRDTVSIFKVPGVRLESEARDIFSPSRRTKTPLAPLAKCW
What is the function of this protein?
Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin.
What are the official names of this protein?
Cyclin-dependent kinase 15, Cell division protein kinase 15.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Protein: RLA2_DICDI
Sequence: MKYLAAYLLASLSGNANAASVTKILQSVGVEVDAARVESVCKELDGKDVQALIAAGKSKVGSVAAAAAPAAATSAAPAAAAAAPAKKVVEEKKEESDDDMGMGLFD
What is the function of this protein?
Plays an important role in the elongation step of protein synthesis.
What are the official names of this protein?
60S acidic ribosomal protein P2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein P1/P2 family.
Protein: ACEK_YERE8
Sequence: MVTKLEQLIAQTILQGFDAQYGRFLEVTAGAQHRFEQADWHAVQQAMKKRIHLYDSHVGLVVEQLKHITDQRCFDVNFLTRVKEIYTGLLPDYPRFEIAESFFNSVYCRLFKHRDLTPDKLFVFSSQPERRFREIPRPLARDFAPKGDLSGMLQVVLNDLPLRLPWENLPRDIGYIATALRQNFTDEQLATARFQVANELFYRNKAAWLVGKLRLADEVYPFLLPIHHNESGGLFIDTCLTSKAEASIVFGFARSYFMVYAPLPAAMVEWLREILPGKSTAELYMAIGCQKHGKTESYREYLTFVHQSSEQFIIAPGVKGMVMLVFTLPSFDRVFKVIKDQFAPQKEVSQTRVLECYQLVKEHDRVGRMADTQEYENFVIDKHRISAELLTELQREVPEKLEDLGDQIIIKHLYMERRMTPLNLYIEQANDQQLKDAIEEYGNAIKQLAAANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPPPRYPEDEMASEPWYSVSPNDVFPEEFRHFLCTDLKVRHFFEEMHSDLFHASYWRGLQQRIKDGHVEDVFAYRRKQRFSQRVIS
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STX3_SCOVN
Sequence: EQLIKKDVKHKDKFAKKSECVRAAAAAFTGGDKS
What are the official names of this protein?
Scolopendra 5848.48 Da toxin.
What is the protein family that this protein belongs to?
Belongs to the scolopendra toxin 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSAA_CITSI
Sequence: MIIRSPEPEVKILVDRDPVKTSFEEWAKPGHFSRTIAKGPETTTWIWNLHADAHDFDSHTSDLEEISRKVFSAHFGQLSIIFLWLSGMYFHGARFSNYEAWLSDPTHIGPSAQVVWPIVGQEILNGDVGGGFRGIQITSGFFQLWRASGITSELQLYCTAIGALIFAALMLFAGWFHYHKAAPKLAWFQDVESMLNHHLAGLLGLGSLSWAGHQVHVSLPINQFLNAGVDPKEIPLPHEFILNRDLLAQLYPSFSEGATPFFTLNWSKYAEFLTFRGGLDPVTGGLWLTDIAHHHLAIAILFLIAGHMYRTNWGIGHGLKDILEAHKGPFTGQGHKGLYEILTTSWHAQLSLNLAMLGSLTIIVAHHMYSMPPYPYLATDYGTQLSLFTHHMWIGGFLIVGAAAHAAIFMVRDYDPTTRYNDLLDRVLRHRDAIISHLNWVCIFLGFHSFGLYIHNDTMSALGRPQDMFSDTAIQLQPVFAQWIQNTHALAPGGTAPGATASTSLTWGGVDLVAVGGKVALLPIPLGTADFLVHHIHAFTIHVTVLILLKGVLFARSSRLIPDKANLGFRFPCDGPGRGGTCQVSAWDHVFLGLFWMYNAISVVIFHFSWKMQSDVWGSISDQGVVTHITGGNFAQSSITINGWLRDFLWAQASQVIQSYGSSLSAYGLFFLGAHFVWAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPATQPRALSIVQGRAVGVTHYLLGGIATTWAFFLARIIAVG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PSI-A, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RSXB_SHISS
Sequence: MNAIWIAVAAVSLLGLAFGAILGYASRRFAVEDDPVVEKIDEILPQSQCGQCGYPGCRPYAEAISCNGEKINRCAPGGEAVMLKIAELLNVEPQPLDGEAQELTPARMVAVIDENNCIGCTKCIQACPVDAIVGATRAMHTVMSDLCTGCNLCVDPCPTHCISLQPVAETPDSWKWDLNTIPVRIIPVEHHA
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit B, Rsx electron transport complex subunit B.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: CARDA_CYNCA
Sequence: MGTSIKANVLALFLFYLLSPTVFSVSDDGLIRIGLKKRKVDRIDQLRGRRALMEGNARKDFGFRGTVRDSGSAVVALTNDRDTSYFGEIGIGTPPQKFTVIFDTGSSVLWVPSSKCINSKACRAHSMYESSDSSTYKENGTFGAIIYGTGSITGFFSQDSVTIGDLVVKEQDFIEATDEADNVFLHRLFDGILGLSFQTISVPVWYNMLNQGLVKERRFSFWLNRNVDEEEGGELVFGGLDPNHFRGDHTYVPVTYQYYWQFGIGDVLIGDKSTGFCAPGCQAFADSGTSLLSGPTAIVTQINHAIGANGVMNQQCKTVVSRYGRDIIEMLRSKIQPDKICSHMKLCTFDGARDVSSIIESVVDKNNDKSSGGIHDEMCTFCEMAVVWMQNEIKQSETEDNIINYANELCEHLSTSSEELQVDCNTLSSMPNVSFTIGGKKFGLTPEQYILKVGKGEATQCISGFTAMDATLLGPLWILGDVFMRPYHTVFDYGNLLVGFAEAA
What is the function of this protein?
Aspartic proteinase with a high preference for bonds between hydrophobic residues.  Cleaves alpha-lactalbumin but not beta-lactoglobulin.
What are the official names of this protein?
Procardosin-A.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Microsome membrane. Protein storage vacuole. Secreted, cell wall. Secreted, extracellular space, extracellular matrix. Note=Procardosin-A is associated with the microsomal membranes, the mature form is secreted.
Protein: RACA_BACCZ
Sequence: MEYKTPFIAKKLGVSPKAVVRIAQQLNLTIEKNKYGHFIFTQDDLDQMLEYHRSQIEQSQNTHPTQKTSSNDVEELKTQVNTIVQNISSHDFEQLAAQLNTITRRLDRMEEQMQDKANDVVTYQLLQHRREMEEMLERIQKLEAGLKKEEPIYITPDTKPTYEREKKPKRRKMIFSIFGL
What is the function of this protein?
Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore.  Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure.
What are the official names of this protein?
Chromosome-anchoring protein RacA.
What is the protein family that this protein belongs to?
Belongs to the RacA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to cell poles and nucleoid.
Protein: RLMC_VIBCM
Sequence: MQCEFFIQKRCTSCHQCAQPYSQQVENKDQQLRELIAPAMDVQWLPPVTSADTAFRNKAKMVVLGAAHAPILGIEDAQGQPLSLVTCPLYPQPMQELLAYLENWIRIAGIPPYNKLKKKGELKFILLTRSENSGQFMLRFVARSHAVLERIERNLPTLIAAFPTIEVVSVNIQPVHMARLEGEEEIFLTETQSLLEQFNDVPMVIRPKSFFQTNPQVAEQLYATARAWVREIAPTQMWDLFCGVGGFALHCAAPNTAVTGIEIEPEAIASAQRSAQMMGIDNLSFAALDSAKFSQSQMSAPELVLVNPPRRGLGSELTAQLEALAPQHILYSSCNPQTMVKDIAELASYQMSRVQWFDMFPHTDHAEVLTLLVRK
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC, 23S rRNA(m5U747)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.
Protein: ENGB_LACDB
Sequence: MIINQSEFSVSAVKASQYPEGGLDEIALAGRSNVGKSSFINTLLQRKNLARTSSSPGKTQTLNFYRVDSDQADFYLVDVPGYGYAKVSKKQREEFGEMIQDYLETRAYLKGLILMIDGRHEPTVDDIAMYDYAQYLNLPILLVATKMDKIKKNAFNKTEAAFRKHLNLNKDNVTFLPFSSVTKLNVDQVKDWIQARLYEE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: ATG13_CANGA
Sequence: MSNGNDNQVIELIQNFFLKSAGLVTTVESNRYSLDDTSIEFDDEWFDMNIDVLHDLPPIIDKWTNFDGTQELPPLVIETFLDLHLLPSSYTVRLRDDESHLWAVSKGNKKSEIVLERWLIELDKESTSFKNHVQSGSGVSPEKLDQQLRLLFRYLFTLLQLLPSNDLMMALNNQSESHNTPIPVDIKTRILDGSQPILSKGRIGLSRPIISSYSNIINNSNIPAHLEQKKITPVWTKYGLLRISVSYRRDCQFIFQDLNEDNSPNTQITNQPAKTNEISISLSPRSKNDLNQISHPSWQKKFISSSKQFQPFIVGSVGSANTPNQNSSRNPSNSSVVGPHYHPQHRLSIGSSTSVSTQPNYEGTSVGSTSKFASSFNNLRRHSSVRYHESTEKLAKTDKNNYEDTDDLMEFVRLIEAKPELQPKKGLSGLQDKNLSGSILRYQKLRPSNDMLSEDLALSVSIDPIHGSQRRNSNSHSHSPVASFSPSGHFSSINSKLSQPHLAVRGSSSTVNSRRNSVDKVLASALSPIYGGDIPEYHTKSHNPVFNEVDDEEEGNDDLLVNKIPININKHKMSTSPRSIDSISNSLTRNRTPFRQPYQYSQPTTIATQAYAKMHRPTVRSSDAISEINSRKGDNFHQLINDNDEDDLVFFMSDMNLPRE
What is the function of this protein?
Activates the ATG1 kinase in a nutritional condition dependent manner through the TOR pathway, leading to autophagy.  Also involved in cytoplasm to vacuole transport (Cvt) and more specifically in Cvt vesicle formation.  Seems to play a role in the switching machinery regulating the conversion between the Cvt pathway and autophagy.  Finally, ATG13 is also required for glycogen storage during stationary phase (By similarity).
What are the official names of this protein?
Autophagy-related protein 13.
What is the protein family that this protein belongs to?
Belongs to the ATG13 family. Fungi subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure.
Protein: ARGP_ECO81
Sequence: MKRPDYRTLQALDAVIRERGFERAAQKLCITQSAVSQRIKQLENMFGQPLLVRTVPPRPTEQGQKLLALLRQVELLEEEWLGDEQTGSTPLLLSLAVNADSLATWLLPALAPVLADSPIRLNLQVEDETRTQERLRRGEVVGAVSIQHQALPSCLVDKLGALDYLFVSSKPFAEKYFPNGVTRSALLKAPVVAFDHLDDMHQAFLQQNFDLPPGSVPCHIVNSSEAFVQLARQGTTCCMIPHLQIEKELASGELIDLTPGLFQRRMLYWHRFAPESRMMRKVTDALLDYGHKVLRQD
What is the function of this protein?
Controls the transcription of genes involved in arginine and lysine metabolism.
What are the official names of this protein?
HTH-type transcriptional regulator ArgP.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: PITC_DICDI
Sequence: MESTASTSDSASAITTGLSEVDINQQSPPIILKEGEIFDPLKNLNEKQLEAFKEIKSNFSDLTDPTDIAFCTDMCFLRYLRARNYIVSKSEKMLRDTLEWRKKFRPQDIQLGGDIREIGSAGCVYVNKRDKKGRPIIFAVPRNDTLKNVPSELKFKNLVYWLEQGFSRMDEPKGIEQFCFIVDYKDFGSGNMDMKTNLEAMHFLLDHCPERMGQSLFLDPPALFWFAWKIISPFLNEVTLSKVRFINSKKVDGKRTFAELLEYVDIENLEQNLGGNLDYNYNIDEYLKENPDPIVDTPPITFSTETDSKKQKKEKKKEEKEKKKEEKEKKKEEKEEKKKEKEEKKKLKKEASFTKQQENADEVD
What is the function of this protein?
Has phosphatidylinositol transfer activity (By similarity).
What are the official names of this protein?
Phosphatidylinositol transfer protein 3, CRAL-TRIO domain-containing protein pitC, Random slug protein 5.
Protein: CR15_RANCA
Sequence: GLLSVLGSVVKHVIPHVVPVIAEHL
What is the function of this protein?
Antibacterial peptide, that adopts an alpha helical conformation which can disrupt bacterial membranes.  Each caerin displays a different antimicrobial specificity.
What are the official names of this protein?
Caerin-1.5.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Caerin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NUDC_VIBPA
Sequence: MLRKGDVNRVANAYWCVVAGSEIWLVDGAVPFGSAEQFSLPEENARQIGDYLGSPVMWINFADLEQDLPLVSLRDCLHFPEPLFMLLSKAIQYGHMTQSLRFCPQCGGRNFLNNNQFAMQCGECRTLHYPRIFPCIIVAVRKENQILLAQHPRHRNGMYTVIAGFLEAGETLEDCVAREVHEETGIHVKNIRYFGSQPWAFPSSMMMAFLADYDSGELNPDYTELSDAQWFGVKEMPPVAPTGTIARALIEQTISDILSD
What is the function of this protein?
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.  The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing.  Has preference for mRNAs with a 5'-end purine.  Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.
What are the official names of this protein?
NAD-capped RNA hydrolase NudC, DeNADding enzyme NudC, NADH pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudC subfamily.
Protein: SSRP_ENTFA
Sequence: MPKGEGKLIAQNRKARHDYSIIDTVEAGLVLQGTEIKSIRNGRINLKDGFARIRNGEAFLYNVHISPYEQGNIFNHDPLRTRKLLLHKKQINKLIGETKNTGITLVPLKVYIKDGYAKVLIGLAKGKKQYDKREDLKRKEVDRQISRTLKNNRR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: TOR_SCHHA
Sequence: PQCESETNFHYDIPPGYKDDVLVDVNNMSPSLVSDTQKHERGSHEVKIKHFSPYIAVCVTTFSLAFCCFMVHAAITRQPTHLLPFFFIQVFDLIICLIHILGFMSSTSDIRLVIHTKTGPIYIKSTGLTFIILSISCMMLAFKAYCLGMVWDCYKYLMLNRRGNLLDDWYSDQWGHLSTFWSLLRTGRNRGNNSIGNSGSPNEPNTRPRPDTITYDPANDLPKYEDILKIRNAYAPPPYYCSNTNGNVNTTTTDAVTTNTTITSATTANATTTITTNANTNTSTTTSVISPLTTTNKDDTQINNASSNAHSSC
What is the function of this protein?
Cell surface receptor that binds to human complement C2a protein.  This results in inhibition of the classical and lectin pathways of complement activation, probably due to interference with binding of C2a to C4b and interference with cleavage by C1 or MASP2 such that C3 convertase cannot be formed.  This infers resistance to complement-mediated cell lysis, allowing parasite survival and infection.
What are the official names of this protein?
Tetraspanning orphan receptor, Complement C2 receptor inhibitor tetraspanning, Complement C2 receptor inhibitor trispanning, Trispanning orphan receptor, Sh-TOR.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Located on the surface tegumental plasma membrane, and tegumental surface pits of adult schistosomes so in contact with host blood plasma.
Protein: ATPG_CALS4
Sequence: MGKRDIALRIKSVKEVRKITRAMYLISASKFQKAKGMLDRVRPYYYRVQTVMKDILLHTGEVTSRYLEKKDVPEKQDKRKVFLIVTGDKGLCGAYNHNVIKASIELIKNEKANLKVVGEVGRRYFIKKGYDVDRDFLYTAQNPTVDLAAEIAEILLKEYNNGDADEIWAVYTEMKGLSQKVRTLRLLPLDVENFMSIAAEEEEAVEEHVVIDSDMIYEPSPSEVFDAIVPEYLKGLIYSILVQAFASEHFSRMVAMDGATSNADEMIEKLTLLYNKLRQASITQEIIEIITGASV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.