PharMolix/UniProtQA huggingface dataset:
Protein: RFC2_PHANO
Sequence: MADFFNLKARQQAAAQASSSKTPTSKQESNRLQPWVEKYRPKTLSEVTAQDNTIQILSRTLQSSNLPHMLFYGPPGTGKTSTILALAKQLYGPELMKSRVLELNASDERGISIVRQKVKDFARQQLSVAPTYNVMTEDKDGGEAKMVRYRDKYSCPPFKIIVLDEADSMTQDAQSALRRTMETYSRMTRFCLVCNYVTRIIDPLASRCSKFRFKSLDQGNAVRRVDDIAKLEDVKLDAGVSEELVRVADGDLRKAITFLQSAARLVGATQTAGRKKKVVVDDEDEMDIDPPSAPSKTTISLEQIAEIAGVIPAPTLASFSDALFPKSAAKSIRYNEIAKVVENMIAEGWSASQTVSQLYEQVMFDERVEDIKKVRLAGVFSETDKRLVDGGDEHLAVLDLGVRVAGVLCMG
What is the function of this protein?
The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1.  Subunit 2 binds ATP and single-stranded DNA (By similarity).
What are the official names of this protein?
Replication factor C subunit 2, Replication factor C2.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PETG_CYAP4
Sequence: MVEPLLCGIVLGLIPITLAGLFVAAYQQYKRGKELGV
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: YBEY_CHLPN
Sequence: MTQEKIKIHVSNEQTCIPIHLVSVEKLVLTLLEHLKVTTNEIFIYFLEDKALAELHDKVFADPSLTDTITLPIDAPGDPAYPHVLGEAFISPQAALRFLENTSPNQEDIYEEISRYLVHSILHMLGYDDTSSEEKRKMRVKENQILCMLRKKHALLTA
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_SALPC
Sequence: MTDVTLKALAAERQVSVDRLVQQFADAGIRKSADDSVSAQEKQTLLAHLNREAVSGPDKLTLQRKTRSTLNIPGTGGKSKSVQIEVRKKRTFVKRDPQEAERLAAEEQAQREAEEQARREAEEQAKREAQQKAEREAAEQAKREAAEKAKREAAEKDKVSNQQTDDMTKTAQAEKARRENEAAELKRKAEEEARRKLEEEARRVAEEARRMAEENKWTATPEPVEDTSDYHVTTSQHARQAEDENDREVEGGRGRGRNAKAARPAKKGKHAESKADREEARAAVRGGKGGKRKGSSLQQGFQKPAQAVNRDVVIGETITVGELANKMAVKGSQVIKAMMKLGAMATINQVIDQETAQLVAEEMGHKVILRRENELEEAVMSDRDTGAAAEPRAPVVTIMGHVDHGKTSLLDYIRSTKVASGEAGGITQHIGAYHVETDNGMITFLDTPGHAAFTSMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAAGVPVVVAVNKIDKPEADPDRVKNELSQYGILPEEWGGESQFVHVSAKAGTGIDELLDAILLQAEVLELKAVRKGMASGAVIESFLDKGRGPVATVLVREGTLHKGDIVLCGFEYGRVRAMRNELGQEVLEAGPSIPVEILGLSGVPAAGDEVTVVRDEKKAREVALYRQGKFREVKLARQQKSKLENMFANMTEGEVHEVNIVLKADVQGSVEAISDSLLKLSTDEVKVKIIGSGVGGITETDATLAAASNAILVGFNVRADASARKVIESESLDLRYYSVIYNLIDEVKAAMSGMLSPELKQQIIGLAEVRDVFKSPKFGAIAGCMVTEGTIKRHNPIRVLRDNVVIYEGELESLRRFKDDVNEVRNGMECGIGVKNYNDVRVGDMIEVFEIIEIQRTIA
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P100_HHV6Z
Sequence: MDLKAQSIPFAWLDRDKVQRLTNFLSNLENLENVDLREHPYVTNSCVVREGEDVDELKTLYNTFILWLMYHYVLSKRKPDYNAIWQDITKLQNVVNEYLKSKGLNKGNFENMFTNKEKFESQFSDIHRALLRLGNSIRWGSNVPIDTPYVNLTAEDSSEIENNLQDAEKNMLWYTVYNINDPWDENGYLVTSINKLVYLGKLFVTLNQSWSKLEKVAMSQIVTTQNHLSGHLRKNENFNAVYSQRVLQTPLTGQRVESFLKIITSDYEIIKSSLESYSASKAFSVPENGPHSLMDFASLDGRMPSDLSLPSISIDTKRPSADLARLKISQPKSLDAPLKTQRRHKFPESDSVDNAGGKILIKKETLGGRDVRATTPVSSVSLMSGVEPLSSLTSTNLDLRDKSHGNYRIGPSGILDFGVKLPAEAQSNTGDVDLLQDKTSIRSPSSGITDVVNGLANLNLRQNKSDVSRPWSKNTAANADVFDPVHRLVSEQTGTPFVLNNSDVAGSEAKLTTHSTETGVSPHNVSLIKDLRDKDGFRKQKKLDLLGSWTKEKNDKAIVHSREVTGDSGDATETVTARDSPVLRKTKHANDIFAGLNKKYARDVSRGGKGNSRDLYSGGNAEKKETSGKFNVDKEMTQNEQEPLPNLMEAARNAGEEQYVQAGLGQRVNKILAEFTNLISLGEKGIQDILHNQSGTELKLPTENKLGRESEEANVERILEVSDPQNLFKNFKLQNDLDSVQSPFRLPNADLSRDLDSVSFKDALDVKLPGNGEREIDLALQKVKAGERETSDFKVGQDETLIPTQLMKVETPEEKDDVIEKMVLRIRQDGETDEETVPGPGVAESLGIAAKDKSVIAS
What are the official names of this protein?
Large structural phosphoprotein, 100 kDa phosphoprotein, pp100, Major antigenic structural protein.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae large structural phosphoprotein family.
What are the subcellular locations of this protein?
Virion tegument. Note=Also found in dense bodies.
Protein: FMT_DESPS
Sequence: MVSSQIESEEKSLRIIFMGTPDFASSNLRALLAGPDQVVAVVTQPDRPKGRGKKLTSPPVKVIAEEAGLPVLQPTKVRTDEFLEALAAYAPDLIVVTAYGRILPKPILDLAPLGCINVHGSLLPKYRGAAPIQWAVIQGDDEVGVTTMQMDEGMDTGDILLRKIIIPSPDETAGTLFDKLAELGTSALLETIEGLKKGTIRAEAQDHAQATEAPMLSKNDGLIDWSRTATELESLIRGMDPWPSAFCFLEGKRLRLFMPEVSYQKTDAQPGAVLRAGRDGLLIATGKNCLLVKEIQPEGKKRMTVEAFLCGAKIGAETVLKTT
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: GUMI_XANCE
Sequence: MSASASLPVTRAAAAPRITVLFSTEKPNANTNPYLTQLYDALPDAVQPRFFSMREALLSRYDVLHLHWPEYLLRHPSKMGTLAKQACAALLLMKLQLTGTPVVRTLHNLAPHEDRGWRERALLRWIDQLTRRWIRINATTPVRPPFTDTILHGHYRDWFATMEQSTTLPGRLLHFGLIRPYKGVEVLLDVMRDVQDPRLSLRIVGNPATPXMRTLVETACAQDARISALLAYVEEPVLAREVSACELVVLPYKQMHNSGTLLLALSLARPVLAPWSESNAAIADEVGPGWVFLYEGEFDAALLSGMLDQVRAAPRGPAPDLSQRDWPRIGQLHYRTYLEALGKDGDAAL
What is the function of this protein?
Nonprocessive beta-mannosyltransferase that catalyzes the transfer of a mannose residue from GDP-mannose to glucuronic acid-beta-1,2-mannose-alpha-1,3-glucose-beta-1,4-glucose-PP-polyisoprenyl to form the lipid-linked pentasaccharide repeating unit of xanthan, Man-GlcA-Man-Glc(2)-PP-Pol.  Is involved in the biosynthesis of the exopolysaccharide xanthan.  To a lesser extent, can also use ADP-Man and even GDP-Glc as sugar donor substrates in vitro.  Is unable to transfer a Man residue to the free-tetrasaccharide GlcA-Man-Glc(2) used as an acceptor, which indicates that the diphosphate group and the lipid moiety in the acceptor substrate are of major importance for acceptor binding and catalysis.
What are the official names of this protein?
GDP-mannose:glycolipid 4-beta-D-mannosyltransferase, GlcA-beta-(1->2)-D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphosphoundecaprenol 4-beta-mannosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 94 family.
What are the subcellular locations of this protein?
Cell inner membrane. Note=Monotopic integral membrane protein, mostly cytoplasmic.
Protein: RL7_HELPJ
Sequence: MAISKEEVLEYIGSLSVLELSELVKMFEEKFGVSATPTVVAGAAVAGGAAAESEEKTEFNVILADSGAEKIKVIKVVREITGLGLKEAKDATEKTPHVLKEGVNKEEAETIKKKLEEVGAKVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: FDHE_HAEIN
Sequence: MSIKILSESEIKQVANSYQAPAVLFANPKNLYQRRAKRLRDLAQNHPLSDYLLFAADIVESQLSTLEKNPLPPQQLEQLNTIEPLNAKTFKRNSIWREYLTEILDEIKPKANEQIAATIEFLEKASSAELEEMANKLLAQEFNLVSSDKAVFIWAALSLYWLQAAQQIPHNSQVENAENLHHCPVCGSLPVASMVQIGTSQGLRYLHCNLCESEWNLVRAQCTNCNSHDKLEMWSLNEELALVRAETCGSCESYLKMMFQEKDPYVEPVADDLASIFLDIEMEEKGFARSGLNPFIFPAEEA
What is the function of this protein?
Necessary for formate dehydrogenase activity.
What are the official names of this protein?
Protein FdhE homolog.
What is the protein family that this protein belongs to?
Belongs to the FdhE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBX1A_XENLA
Sequence: MISAISSPWLTQLSHFCDVAAFTANSLSSLNATGGYHLSPSPGDPYSQHEPHYEPCSASQHSYSFGHACPEPESGASSSSCASSTPGSGSTGSSSSNKAPVKKNPKVANINVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKIFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDPEDWPRNHRPGSLPLMNAFARSRNPVSSPTQNGSDKDGDGRREYERDASGTPLHGDAAHQQLMSRVLSLSLPVPGGLVPLSTGRPSPPHELRLDPHSQGSEPLHHHPYKYPTSYDRYLGAKTRPAPYPLPTIRGHGYHHHHMNPAAANMYSGAGAPGSYEYGPR
What is the function of this protein?
Probable transcriptional regulator involved in developmental processes (By similarity).  Binds to the palindromic T site 5'-TTCACACCTAGGTGTGAA-3' DNA sequence (By similarity).  Induces pre-placodal ectoderm (PPE) gene expression in regions where RIPPLY3 is absent.  Plays a role in the formation of the anteroposterior (AP) axis during embryonic development; required to establish the posterolateral border of the pre-placodal ectoderm (PPE) acting downstream of the retinoic acid receptor (RAR) signaling.
What are the official names of this protein?
T-box transcription factor TBX1-A, T-box protein 1-A.
What are the subcellular locations of this protein?
Nucleus.
Protein: PFEA_PSEAE
Sequence: MSSRALPAVPFLLLSSCLLANAVHAAGQGDGSVIELGEQTVVATAQEETKQAPGVSIITAEDIAKRPPSNDLSQIIRTMPGVNLTGNSSSGQRGNNRQIDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDSRGDTNWVPADQVERIEVIRGPAAARYGNGAAGGVVNIITKQAGAETHGNLSVYSNFPQHKAEGASERMSFGLNGPLTENLSYRVYGNIAKTDSDDWDINAGHESNRTGKQAGTLPAGREGVRNKDIDGLLSWRLTPEQTLEFEAGFSRQGNIYTGDTQNTNSNNYVKQMLGHETNRMYRETYSVTHRGEWDFGSSLAYLQYEKTRNSRINEGLAGGTEGIFDPNNAGFYTATLRDLTAHGEVNLPLHLGYEQTLTLGSEWTEQKLDDPSSNTQNTEEGGSIPGLAGKNRSSSSSARIFSLFAEDNIELMPGTMLTPGLRWDHHDIVGDNWSPSLNLSHALTERVTLKAGIARAYKAPNLYQLNPDYLLYSRGQGCYGQSTSCYLRGNDGLKAETSVNKELGIEYSHDGLVAGLTYFRNDYKNKIESGLSPVDHASGGKGDYANAAIYQWENVPKAVVEGLEGTLTLPLADGLKWSNNLTYMLQSKNKETGDVLSVTPRYTLNSMLDWQATDDLSLQATVTWYGKQKPKKYDYHGDRVTGSANDQLSPYAIAGLGGTYRLSKNLSLGAGVDNLFDKRLFRAGNAQGVVGIDGAGAATYNEPGRTFYTSLTASF
What is the function of this protein?
Specific receptor for the siderophore ferric enterobactin.
What are the official names of this protein?
Ferric enterobactin receptor.
What is the protein family that this protein belongs to?
Belongs to the TonB-dependent receptor family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: HLAH_HUMAN
Sequence: MVLMAPRTLLLLLSGALALTQTWARSHSMRYFYTTMSRPGAGEPRFISVGYVDDTQFVRFDSDDASPREEPRAPWMEREGPKYWDRNTQICKAQAQTERENLRIALRYYNQSEGGSHTMQVMYGCDVGPDGPFLRGYEQHAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAARRAEQRRVYLEGEFVEWLRRYLENGKETLQRADPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLTLRWEPSSQPTVPIVGIVAGLVLLVAVVTGAVVAAVMWRKKSSDRKGGSYSQAASSNSAQGSDVSLTA
What is the function of this protein?
Involved in the presentation of foreign antigens to the immune system.
What are the official names of this protein?
Putative HLA class I histocompatibility antigen, alpha chain H, HLA-12.4, HLA-AR, MHC class I antigen H.
What is the protein family that this protein belongs to?
Belongs to the MHC class I family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RL33_SYNE7
Sequence: MAKAKGARIVITLECTECRSNTAKRSPGVSRYTTQKNRRNTTERLEIKKFCPHCNKHTAHKEIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: MUTL_RHIE6
Sequence: MAIRQLSETLINQIAAGEVIERPASAAKELIENALDAGATRIEIATAGGGKALLRVSDNGSGMEATDLELAVRRHCTSKISETLEDIRTLGFRGEALPSIGSVARLNIASRRRDSAGGHEIAVAGGKIVHIRPAAANPGTIVEVRDLFFATPARLKFLKSEKAEAGAITEIVKRMAIAFPAVRFVLSGSDRTTLEFPATGDDHLARMAQVLGKEFRDNAILLDAVREDISLTGFAGVPTFNRGNSAHQYAFVNGRPVQDKLILSAIRGAYAETIPSGRYPVAVLSITLDPALVDVNVHPAKSDVRFRDPGLVRGLIVGAIREALARDGSRAATTGASDMLRAFRPGFQPHAQRPQAPWSAETSPFRPYPPAAGFSERPQASFDRLSMPTARAELQPSPQPGAPEPAASAETTGRYPLGAARAQIHANYIVAQTEDGLVIVDQHAAHERLVFEAMRKALHSKRLASQVLLIPEIIDLPEEDCDRLMQHAAELSELGLAIERFGPGAIAVRETPAMLGEVDAHGLIRQLADEIAEWDTASGLSAKLEYVAATMACHGSVRSGRRLRPEEMNALLREMEVTPGSGQCNHGRPTYIELKLSDIERLFGRS
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: RNH2_YERPG
Sequence: MSETFIYPQANLIAGVDEVGRGPLVGAVVTAAVILDPNRPIVGLADSKKLSEKRRLSLYDEITEKALSWSLGRAEPEEIDQLNILHATMLAMQRAVSGLHIVPDYVLIDGNRCPKLQMPSLAVVKGDSRVAEISAASILAKVTRDREMTELDLLFPEYGFAQHKGYPTAFHLEKLAALGATVHHRRSFGPVKRVLGLV
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROA_HAES1
Sequence: MEKLTLSPISRIDGEINLPGSKSLSNRALLLAALAKGTTQVTNLLDSDDIRYMLNALKALGVNYQLSDDKTVCVVEGIGGAFQWQNGLSLFLGNAGTAMRPLAAALCLKGDTESEVILTGEPRMKERPIKHLVDALRQTGANIQYLENEGYPPLAIRNQGIFGGKVQIDGSISSQFLTALLMAAPLGEGDMEIEILGELVSKPYIDITLAMMKDFGINVEHYNYQRFLIKGKQYYISPQTYLVEGDASSASYFLAAAAIKGKVKVTGIGRNSIQGDRLFADVLAQMGAKVTWGEDFIQVEKSELKGIDMDMNHIPDAAMTIAITALFAQGETVIRNIYNWRVKETDRLTAIATELRKLGAEVEEGEDFIRIQPLALDKFKHAEIATYNDHRIAMCFSLIALSDTSVTILDPACTAKTFPTYFSEFEKISKNQ
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPG_GRABC
Sequence: MSYRPYQQIERRKSRQIHVGKVAVGGDAPISVQTMTNTLTTDAEATIAQIRRAELAGVDIVRVSCPDQESTIALKEIVREVNVPIVADIHFHYRRAIEAAEAGAACLRINPGNIGSAERVREVVKAARDHGCAIRIGVNAGSLERHLLEKYGEPNPDALVESALEHAKILQDHDFHEFKISVKASDVFLAVAAYQQLAEVCDHPLHIGITEAGGRRTGTVKSAIGLGNLLWAGVGDTMRVSLSAEPEEEVHVGWEILKGLGLRHRGVKIISCPSCARQGFNVIETVAALEERLAHIQTPLTLSIIGCVVNGPGEALMTDIGLTGGGGGRHMIYNAGKTDHTIAADGMVDHIVTLVEEKAARIVEEEAAAKAAAEQAAQEAALQHETV
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: ACCD_CAUVC
Sequence: MAMAEPQDPKKGDKKTAERRGGGWLSRIAPGVRGAFAKRETPENLWVKCPDTGEMIFRSDLEAALWVTPAGRHMRIGPEARFKFTFDDGQYEALPTPPVVEDPLKFSDGKPYKDRLVAARKATGEPDAMAIGYGKVGGVDAVVLVQDFAFMGGSLGMAAGEGFIAAAKAALERQVPMIAFTAAGGARMQEGALSLMQMARTTLAINELKDAALPYVVVLTDPTTGGVTASYAMLGDIHLAEPGALIGFAGPRVIEQTIRETLPPGFQRSEYLVEKGMVDRVTHRKELPEVLGSLLGTLMMGRKRQAA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERD22_MOUSE
Sequence: MNIFRLTGDLSHLAAIVILLLKIWKTRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYNTSMKLIYIACSYATVYLIYMKFKATYDGNHDTFRVEFLVVPVGGLSFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLVNWIWRFYFEGFFDLIAVVAGVVQTILYCDFFYLYITKVLKGKKLSLPA
What is the function of this protein?
Membrane receptor that binds the K-D-E-L sequence motif in the C-terminal part of endoplasmic reticulum resident proteins and maintains their localization in that compartment by participating to their vesicle-mediated recycling back from the Golgi (By similarity).  Binding is pH dependent, and is optimal at pH 5-5. 4 (By similarity).
What are the official names of this protein?
ER lumen protein-retaining receptor 2, KDEL endoplasmic reticulum protein retention receptor 2, KDEL receptor 2.
What is the protein family that this protein belongs to?
Belongs to the ERD2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPI-coated vesicle membrane; Multi-pass membrane protein. Note=Localized in the Golgi in the absence of bound proteins with the sequence motif K-D-E-L. Trafficks back to the endoplasmic reticulum together with cargo proteins containing the sequence motif K-D-E-L.
Protein: TYSY_METCA
Sequence: MRPYLDLLRDILDHGCPKGDRTGTGTLSVFGRMMRFDLSRGLPLVTTKKLHLPSIIHELLWFVSGSTNVRDLQRHGVTIWDEWADDNGELGPVYGRQWRNWNGAIDQLAGLVEQLRRNPGSRRLLVSAWNPSDLDAMALPPCHYAFQCHVADGRLSLMFQMRSADVFLGLPFNIAGYALLTHMLAQQTGYEPGELIWCGGDVHLYLNHLEQARLQLTREPYPPPTLKLARKPGSLFDYRYEDFVVEDYQAHPHIKAAVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DSBD_HAEDU
Sequence: MLKRFFLLLSSLLLVCNVQAGLFNNKPQYLTAAEAFIFSSSQQDGQLQLHWQIADGYYLYQKEIQLSAQNATLGDVTFPTAEKYQDEFFGEVAIFRDQLKLPVKLTDLKENPSLKIRYQGCTKGFCYPPETVVIPLNPSLQGNNSANSAALPSTIATPNAPQTELAENLSNNYLSIFGFLLLGIGLAFTPCVLPMLPLLSAIVIGHKNRPNTSRALLLSFTYVQGMALTYTLLGLTVAAIGLPFQVALQSPAVLISLAVLFTLLAASMFGLFEIRLPNTWQQKLNALSQQQQGGAVGNVFIMGIIAGLVASPCTSAPLSGALLYVAQSGNLLIGGLALYLLALGMGLPLILITVFGNQILPKSGEWLFKVKTAFGFVMLALPIFLISRILPSHYEPFLWSTLALAFLGWLISSLNYSTMLKQAVRILLFIAFGLTAYPWANLVWQTTSNTAQPTTPHLAMEKITSLTELEQKLTAYQGKKVMLDLYADWCVACKEFEKYTFTDPQVQQQLATMAVLQIDMTKNSAENTALMKHFNVLGLPTILFFDENGHEMTNVRITGFLTANQFLAWLNRL
What is the function of this protein?
Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes.  Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm.  This transfer involves a cascade of disulfide bond formation and reduction steps.
What are the official names of this protein?
Thiol:disulfide interchange protein DsbD, Protein-disulfide reductase, Disulfide reductase.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. DsbD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: COBQ_DESVH
Sequence: MKSPTPALMLQGTSSNAGKSILTAAFCRILLQDGYRVAPFKAQNMALNSHVTADGLELGRAQAVQAAACRLDVDVRMNPVLLKPNSDTGSQVVVMGRPVGNMRVREYMAYKPVAFDAARAAYDSLAADVDVMVLEGAGSPAEVNLKAHDIVNMAMARHAEAKVLLVGDIDRGGVFASLVGTMELLDPWERDLVAGFVLNKFRGDATLLSPAYDVVTGRTGKPFLGVVPWLHDLGLPDEDSVSFRETLAGRAPDVPAGGGMLDIVLVDLPHISNFTDLDALRREPDVAVRVVRSPEQLGSPDAIILPGSKNTLGDLAALRSRGMAEALCALRSAEGGHLGPVIVGICGGFQMMGRFLADPQGVESDHACTEAGLGLLPVTTEMGSAKVLRRTSAKTVSGWCGAGVAAGLMPGTGGGHGGAEVCPGEGYAVHGYEIHHGVTTPDAGGGAVLVCLHESDGSPAGWTTPDGQVWGTYLHGVFDADGFRRGWLDALRVRRGLEPVGRVVARYDLDPALDRLADVVREAVDMGHIYSVLGLSPKGRRQT
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: CAMP_BOTAT
Sequence: MQGFFWKTWLVVALCGTSSSLAHRPLSYGEALELALSIYNSKAGEESLFRLLEAVPQPEWDPLSEGSQQLNFTIKETVCQVEEERPLEECGFQEDGVVLECTGYYFFGETPPVVVLTCVPVGGVEEEEEDEEEQKAEVEKDEEKEDEEKDRPKRVKRFKKFFKKLKNSVKKRVKKFFRKPRVIGVTFPF
What is the function of this protein?
Potent antimicrobial peptide against Gram-negative (MIC=0. 25 ug/ml against E. coli ATCC 25922, MIC=1 ug/ml against P. aeruginosa) and Gram-positive bacteria (MIC=32 ug/ml against E. faecalis, MIC=32 ug/ml against S. aureus) (PubMed:25100358).  Adopts an amphipathic alpha helical conformation, that may allow to partition into the target membrane (By similarity).  Low hemolytic activities have been observed on mammalian cells (PubMed:25100358).  In addition, when tested in vitro on the parasite Trypanosoma cruzi (responsible of the Chagas disease), is able to reduce the number of the three forms (epimastigote, trypomastigote and amastigote) by inducing cell death through necrosis (PubMed:28246023).
What are the official names of this protein?
Batroxicidin, BatxC, Cathelicidin-related antimicrobial peptide, CRAMP, Vipericidin.
What is the protein family that this protein belongs to?
Belongs to the cathelicidin family.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Forms a helical membrane channel in the prey.
Protein: PLSY_BURO0
Sequence: MQILLAALVAYLIGSVSFAVVVSSVMGLADPRSYGSKNPGATNVLRSGNKKAAILTLVGDAFKGWIAVWLARHFGLPDVAIAWVAIAVFLGHLYPVFFRFQGGKGVATAAGVLLAVHPVLGLATALTWLIVAFFFRYSSLAALVAAVFAPVFDVFLFGMPGHNPVAWAVLAMSVLLVWRHRGNISKLLAGQESRIGDKKKAAADGGKA
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.