PharMolix/UniProtQA huggingface dataset:
Protein: CLPP_DRIGR
Sequence: MPIGVPKVPFRSPGEEDAVWVDVYNRLHRERLLFLGQEVDSEISNQLVGLMVYLSIEDDTRDLYLFINSPGGWVIPGIAIYDTMQFVPPDVHTICMGLAASMGSFILVGGEITKRLAFPHARVMIHQPASSFYEAPTGEFILEAEELLKLRETLTRVYVQRTGNPLWVISEDMERDVFMSATEAQAHGIVDVVAVENTGDFT
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: VF301_ASFB7
Sequence: MSEDIRRGPGRPPKKRVVPNFERKGILEKPVRPQSRLEFSYDNPLIFKNLFIYFKNLKSKNILVRCTPTEITFFSRDQSQASFVIATIDGKNVNHYYASDVFWLGINRELVEKMFNSIDRSFLKITIVHRYDKPETLFFIFTDFDIDKECTYQITVSEPELDMDLIEMEKSISEERLKNYPLRWEFTSKQLKKTFSDLSNYTELVTIEKLGGDTPLHLYFQKFNSISYHEMYKSSNKINLTSTIPKSQVFQINVKIAHIKSLASAMVTDKIRILCEENGNLIFQSEMDALMLNTITLNNTI
What is the function of this protein?
Plays a role in the inhibition of host innate immune system by acting as a negatively regulator of type I interferon production.  Mechanistically, interacts with and prevents host IRF3 nuclear localization to inhibit its transcriptional activity.
What are the official names of this protein?
Uncharacterized protein E301R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus E301R family.
Protein: KCY_ACHLI
Sequence: MAGFKVAIDGPAGSGKSSISKNVAHKLGMTHIDTGAMYRAVTLLAIENQIDMNDESQYRFLEDVQITYRDDHIYIGDRIVEKEIRSKAVTDHVSLVSSFPYVRKKLVEIQQKLGETNNIIMDGRDIGTVVLPDADLKIFLIADVRERAKRRQQDKQNQGYEVDIEKLIEEITRRDQLDSQRKISPLKKAEDAIVVDSTHMSLQQTVKKIIELIQSAKGVINE
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PARC_STRP3
Sequence: MSNIQNMSLEDIMGERFGRYSKYIIQERALPDIRDGLKPVQRRILYSMNKDGNTFEKGYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQDWKNREILVEMHGNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVSFAWNFDDTEKEPTVLPAAFPNLLVNGSSGISAGYATDIPPHNLSEVIDAVVYMIDHPKASLEKLMEFLPGPDFPTGGIIQGADEIKKAYETGKGRVVVRSRTEIEELKGGKQQIIVTEIPYEVNKAVLVKKIDDVRVNNKVPGIVEVRDESDRTGLRIAIELKKEADSQTILNYLLKYTDLQVNYNFNMVAIDHFTPRQVGLQKILSSYISHRKDIIIERSKFDKAKAEKRLHIVEGLIRVLSILDEIIALIRSSDNKADAKENLKVSYDFSEEQAEAIVTLQLYRLTNTDIVTLQNEENDLRDLITTLSAIIGDEATMYNVMKRELREVKKKFANPRLSELQAESQIIEIDTASLIAEEETFVSVTRGGYLKRTSPRSFNASSLEEVGKRDDDELIFVKQAKTTEHLLLFTTLGNVIYRPIHELTDLRWKDIGEHLSQTISNFATEEEILYADIVTSFDQGLYVAVTQNGFIKRFDRKELSPWRTYKSKSTKYVKLKDDKDRVVTLSPVIMEDLLLVTKNGYALRFSSQEVPIQGLKSAGVKGINLKNDDSLASAFAVTSNSFFVLTQRGSLKRMAVDDIPQTSRANRGLLVLRELKTKPHRVFLAGGVQSDTSAEQFDLFTDIPEEETNQQMLEVISKTGQTYEIALETLSLSERTSNGSFISDTISDQEVLVARTR
What is the function of this protein?
Topoisomerase IV is essential for chromosome segregation.  It relaxes supercoiled DNA.  Performs the decatenation events required during the replication of a circular DNA molecule.
What are the official names of this protein?
DNA topoisomerase 4 subunit A, Topoisomerase IV subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RSMH_AGRRK
Sequence: MVANSGGGLTDADGGPVRHIPVLLKEVLEALAPAPGKLILDGTFGAGGYTSAILAAGADMIALDRDPTAIAAGQSMVAAHAGRLTLIQSQFSQLADHAPQGGLDGVVLDIGVSSMQLDEAERGFSFSKNGPLDMRMSASGVSAADVVNHAKLADLIRIFVFLGEEKQAPRIAHAIEKRRAEAPFVTTRDLAGLIEIVTPRKAKDKIHPATRVFQALRIFVNDELGELAQALFAAERALKPGGRLVVVTFHSLEDRIVKKFFADRSGRAGGSRHMPMVHERLATFDPIGKPMISASDAEAEINPRARSAKLRAGLRTSVQAEAADLSIFDLPNLASLGKLGG
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_THET2
Sequence: MEAIPVLAGPTGSGKTFLALRLGEEVPVEVVSADATMVYRGLDIGTDKPTPEERARVPHHLVDVLEPHEAMSVARFLALAEEAIAHVLSRGKLPLVVGGTGYYIRALSEGLHDLPPPDPGVQEALWAELEARGLEALLAELARASPEDARRVGKNPRRLVRALEVLRRTGTPPARFPKRPPRFRYKKLVLWPDRAWLFPRLEERAKAQFARGLVEEVRGLLERYPRMPTALQAIGYKEVAGHLLGAYGLEEALERDIRAVKAYAKRQYTWFRHEPGDVVYLPRGGEEAYVGFRDWLRLHFGL
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: PTPRF_HUMAN
Sequence: MAPEPAPGRTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGELLGYRLQYCRADEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQNITTDTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKILYNGQSVEVDGHSMRKLIADLQPNTEYSFVLMNRGSSAGGLQHLVSIRTAPDLLPHKPLPASAYIEDGRFDLSMPHVQDPSLVRWFYIVVVPIDRVGGSMLTPRWSTPEELELDELLEAIEQGGEEQRRRRRQAERLKPYVAAQLDVLPETFTLGDKKNYRGFYNRPLSPDLSYQCFVLASLKEPMDQKRYASSPYSDEIVVQVTPAQQQEEPEMLWVTGPVLAVILIILIVIAILLFKRKRTHSPSSKDEQSIGLKDSLLAHSSDPVEMRRLNYQTPGMRDHPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAHIQKLGQVPPGESVTAMELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT
What is the function of this protein?
The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one.
What are the official names of this protein?
Receptor-type tyrosine-protein phosphatase F, Leukocyte common antigen related, LAR.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.
Protein: HAUS1_BOVIN
Sequence: MEALEEKEAQVAAWLKKIFGDHPIPQYEVNAWTTEILYNLSERNRIRDRDVYLVTEDLKQKAKEYESEAKHLQDLLMESVNFSPASLSSTGSRYLNALVDSAVVLETKDTSLASFIPAVNDLTSDLFRTKSKNEEIKLELAKLEKNLTATLVLEKCLQEDLKKAELHLCTERARVDSRLQNMDFLKAKSEEFRSGIRTAEEQLSARGMDASLSHQSLVALSEKLAELKRQTMPLKKKLESYLDLMPNPSLAQVKIEEAKRELDTIEAELTKRVNMMEL
What is the function of this protein?
Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.
What are the official names of this protein?
HAUS augmin-like complex subunit 1, Coiled-coil domain-containing protein 5.
What is the protein family that this protein belongs to?
Belongs to the HAUS1 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes with the spindle poles in mitotic cells. In interphase, localized at the centrosome and diffusely in the cytoplasm. Localizes to mitotic spindle microtubules (By similarity).
Protein: EXD1_XENLA
Sequence: MLINKVKDLETGKIIPGAQLLFGYNILNVALQKDVEEVPAKHLDKLTIEDREQTSTEQRHADECNQDAERTHRDIDKSQDLRTRTLKVIKHSVDEEEVGYTIIDQFQPIFGPAIRHLQNQKVISIGAVGQNICRHGKLSWLQFATRSRVYLFDVLVLGSKVFKNGLQMVLEDKGILKVIHDCRWLGDILSHQYGIILNNVFDTQVGDVYLFSMETGGFLPHGTRTLEECLIHHLSMLPSKVSFLAHRQTLTKEYHDIWFDRPMDPTLLKLLSLEVTYLMPLRSAMLDAMFSDFTLLVDGYLNAYRRGTADILESPELSVAELPKELQQLRVLQQMRREKALKEYDVNNKGLLTRVEAEKAPRSEASGTKHDAELENVVKLTKSEKSFHQTMTTNAPLLENQTEKQQGALCQKFPVVPNCFPRGPFDYYLYKKWASNDTPTTNVS
What is the function of this protein?
RNA-binding component of the PET complex, a multiprotein complex required for the processing of piRNAs during spermatogenesis.  The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposable elements, preventing their mobilization, which is essential for the germline integrity.  The PET complex is required during the secondary piRNAs metabolic process for the piwil2 slicing-triggered loading of piwil4 piRNAs.  In the PET complex, exd1 probably acts as an RNA adapter.  Exd1 is an inactive exonuclease.
What are the official names of this protein?
piRNA biogenesis protein EXD1, Exonuclease 3'-5' domain-containing protein 1, Exonuclease 3'-5' domain-like-containing protein 1, Inactive exonuclease EXD1.
What is the protein family that this protein belongs to?
Belongs to the EXD1 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Component of the meiotic nuage, also named P granule, a germ-cell- specific organelle required to repress transposon activity during meiosis.
Protein: NUDL_YERPG
Sequence: MSELITGQYLSEFINRFQLQLPQPDNVLTHSHYFSATNRRAAVLIPIICRPEPTLLLTRRADHLRKHAGQVAFPGGKADPDDQSLISTALREAEEEVAIPASVVHVLGKLAPLNSSSGYHVTPIVGLVPANIPFYGNDEEVAGLFEIPLHEALSLSRYHSLDIHREGINHRVYLSWYENQFIWGLTATIIRHLAQQVSI
What is the function of this protein?
Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.
What are the official names of this protein?
Uncharacterized Nudix hydrolase NudL.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. PCD1 subfamily.
Protein: CORE5_ADE02
Sequence: MSKRKIKEEMLQVIAPEIYGPPKKEEQDYKPRKLKRVKKKKKDDDDDELDDEVELLHATAPRRRVQWKGRRVRRVLRPGTTVVFTPGERSTRTYKRVYDEVYGDEDLLEQANERLGEFAYGKRHKDMLALPLDEGNPTPSLKPVTLQQVLPTLAPSEEKRGLKRESGDLAPTVQLMVPKRQRLEDVLEKMTVEPGLEPEVRVRPIKQVAPGLGVQTVDVQIPTTSSTSIATATEGMETQTSPVASAVADAAVQAAAAAASKTSTEVQTDPWMFRVSAPRRPRRSRKYGTASALLPEYALHPSIAPTPGYRGYTYRPRRRATTRRRTTTGTRRRRRRRQPVLAPISVRRVAREGGRTLVLPTARYHPSIV
What is the function of this protein?
Associates loosely with the viral DNA to form an outer shell around the nucleoprotein-DNA complex and links it with the capsid by binding the endosome lysis protein.  Dissociates from the viral genome during entry.  Might be involved in nuclear capsid assembly of the viral particles through its association with NPM1/nucleophosmin.
What are the official names of this protein?
Core-capsid bridging protein, Core protein V.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae core-capsid bridging protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus, host nucleolus. Note=Located inside the capsid (core). Present in 157 copies per virion. Localizes in the nucleoli during infection, then translocates from the nucleoli to the nucleoplasm as the infection progresses and is finally incorporated into the viral particles.
Protein: RS11_PYRFU
Sequence: MSEEQVNIKKKEKWGIAHIYSSFNNTIIHITDITGAETISRWSGGMVVKADRDEPSPYAAMLAARRAAEEALEKGIVGVHIRVRAPGGSKSKTPGPGAQAAIRALARAGLKIGRVEDVTPIPHDGTRPKGGRRGRRV
What is the function of this protein?
Located on the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S11, Small ribosomal subunit protein uS11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: RL2_ARTS2
Sequence: MGIRKYKPTTPGRRGSSVADFTEITRSTPEKSLVRPLPKKGGRNNTGKITTRHKGGGHKRQYRLIDFRRHDKDGVDARVAEIEYDPNRTARIALLHYVDGTKRYIIAPNKLSQGDFVEAGANADIKPGNNLPLRNIPVGTVIHAVELRPGGGAKMGRSAGASIQLVAKEGRFAQLRLPSGEIRNVDVRCRATVGEVGNAEQSNINWGKAGRMRWKGVRPTVRGVAMNPVDHPHGGGEGKTSGGRHPVNPNGKREGRTRRPNKESDKLIVRRRRTGKNKR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: Y2919_MYCBP
Sequence: MTTLKTMTRVQLGAMGEALAVDYLTSMGLRILNRNWRCRYGELDVIACDAATRTVVFVEVKTRTGDGYGGLAHAVTERKVRRLRRLAGLWLADQEERWAAVRIDVIGVRVGPKNSGRTPELTHLQGIG
What are the official names of this protein?
UPF0102 protein BCG_2919c.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: FER_METBA
Sequence: PATVNADECSGCGTCVDECPNDAITLDEEKGIAVVDNDECVECGACEEACPNQAIKVEE
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
Ferredoxin.
Protein: TY22_PITAZ
Sequence: FPPWE
What are the official names of this protein?
Tryptophyllin-T2-2, Pha-T2-2, Tryptophyllin-3.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Tryptophillin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y7323_DICDI
Sequence: MERIQIISNHILPIVQHNNNNKQYYEQQYLLLANNTTDAIMELSEEHEKEESLRKIQCENNGIEYVYKPLFIDFGVHMNNNNNNKTITVDNNNNNNNNNNNNNNK
What are the official names of this protein?
Putative uncharacterized protein DDB_G0275597.
Protein: DC8L2_HUMAN
Sequence: MSHQEGSTDGLPDLGTESLFSSPEEQSGAVAATEASSDIDIATSELSVTVTGDGSDSRDGGFPNDASTENRSSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQALEEWVSSETSALPRPRWQVVTALHQRQLGSRPRFVYEACGARAFVQRFRLQYRLADHVGCVNTVHFNQRGTRLASSGDDLKVIVWDWVRQRPVLNFESGHTNNVFQAKFLPNCGDSTLAMCARDGQVRVAELINASYFNNTKCVAQHRGPAHKLALEPDSPYKFLTSGEDAVVFTIDLRQDRPASKVVVTRENDKKVGLYTITVNPANTYQFAVGGQDQFVRIYDQRKIDKKENNGVLKKFTPHHLVNCDFPTNITCVVYSHDGTELLASYNDDDIYLFNSSHSDGAQYSKRFKGHRNNTTVKGVNFYGPRSEFVVSGSDCGHIFFWEKSSCQIIQFLKGSREGTINCLEPHPYLPVLACSGLDHDVKIWTPTAKAATELTGLKKVIKKNKWERDEDSLHHGSLFDQYMLWFLLRHVTQRGRHQDWRSGEAEFPDEESDESSSTSETSEEEVQDRVQCMPS
What are the official names of this protein?
DDB1- and CUL4-associated factor 8-like protein 2, WD repeat-containing protein 42C.
What is the protein family that this protein belongs to?
Belongs to the WD repeat DCAF8 family.
Protein: ZFP1_WHEAT
Sequence: MSSSAMEALHALIPEQHQLDVEAAAAVSSATSGEESGHVLQGWAKRKRSRRQRSEEENLALCLLMLSRGGKQRVQAPQPESFAAPVPAEFKCSVCGKSFSSYQALGGHKTSHRVKQPSPPSDAAAAPLVALPAVAAILPSAEPATSSTAASSDGATNRVHRCSICQKEFPTGQALGGHKRKHYDGGVGAAASSTELLAAAAAESEVGSTGNGSSAARAFDLNIPAVPEFVWRPCAKGKMMWEDDEEVQSPLAFKKPRLLTA
What is the function of this protein?
Potential transcription factor which binds the nonamer motif 5'-CATCCAACG-3'.  Possibly involved in regulating transcription of the histone H3 and H4 genes.
What are the official names of this protein?
Zinc finger protein 1, WZF1.
What are the subcellular locations of this protein?
Nucleus.
Protein: HFQ_TOLAT
Sequence: MAKGQSLQDPFLNALRRERIPVSIYLVNGIKLQGQVESFDQFVILLKNTVSQMVYKHAISTVVPARPVAHHTAPAAGDSDSQSEE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: DCDA_STAAC
Sequence: MTVKYNQNGELTMDGISLKTIAQSFGTPTIVYDELQIREQMRRYHRAFKDSGLKYNISYASKAFTCIQMVKLVAEEDLQLDVVSEGELYTALEAGFEPSRIHFHGNNKTKHEIRYALENNIGYFVIDSLEEIELIDRYANDTVQVVLRVNPGVEAHTHEFIQTGQEDSKFGLSIQYGLAKKAIDKVQQSKHLKLKGVHCHIGSQIEGTEAFIETAKIVLRWLKEQGIQVELLNLGGGFGIKYVEGDESFPIESGIKDITDAIKSEIKVLGIDAPEIGIEPGRSIVGEAGVTLYEVGTIKEIPEINKYVSIDGGMSDHIRTALYDAKYQALLVNRNEEADDSVTIAGKLCESGDIIIKDAKLPSSVKRGDYLAILSTGAYHYSMASNYNQMQKPSVFFLKDGKAREVIKRQSLRQLIINDTK
What is the function of this protein?
Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine (By similarity).  Plays a role in beta-lactam antibiotic resistance.
What are the official names of this protein?
Diaminopimelate decarboxylase, DAP decarboxylase, DAPDC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
Protein: KARG_CHIOP
Sequence: MADAATISKLEEGFKKLQGATDCKDVFDQLKQTDKHPNKDFGDVNQFVNVDPDGKFVISTRVRLIDDHFLFKEGDRFLQAANACRYWPSGRGIFHNDKKIISMQMGGDLGQVYRRLVSAVNEIEKRVPFSHHDRLGFLTFCPTNLGTTVRASVHIKLPKXEKLEEVAGKYSLQVRGTRGEHTEAEGGVYDISNKRRMGLTEFQAVKEMQDGILELIKIEKEMQ
What are the official names of this protein?
Arginine kinase, AK.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.
Protein: PSAC_SYNPW
Sequence: MSHAVKIYDTCIGCTQCVRACPLDVLEMVPWDGCKAGQIASSPRTEDCVGCKRCETACPTDFLSIRVYLGDETSRSMGLSY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ALDR_MOUSE
Sequence: MASHLELNNGTKMPTLGLGTWKSPPGQVTEAVKVAIDLGYRHIDCAQVYQNEKEVGVALQEKLKEQVVKRQDLFIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTGFKPGPDYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKTIGVSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIEYCHSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKYNKTTAQVLIRFPIQRNLVVIPKSVTPVRIAENLKVFDFEVSSEDMATLLSYNRNWRVCALMSCAKHKDYPFHAEV
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols (PubMed:17381426, PubMed:19010934, PubMed:7851421).  Displays enzymatic activity towards endogenous metabolites such as aromatic and aliphatic aldehydes, ketones, monosacharides, bile acids and xenobiotics substrates.  Key enzyme in the polyol pathway, catalyzes reduction of glucose to sorbitol during hyperglycemia.  Reduces steroids and their derivatives and prostaglandins (PubMed:19010934).  Displays low enzymatic activity toward all-trans-retinal, 9-cis-retinal, and 13-cis-retinal.  Catalyzes the reduction of diverse phospholipid aldehydes such as 1-palmitoyl-2-(5-oxovaleroyl)-sn -glycero-3-phosphoethanolamin (POVPC) and related phospholipid aldehydes that are generated from the oxydation of phosphotidylcholine and phosphatdyleethanolamides (PubMed:17381426).  Plays a role in detoxifying dietary and lipid-derived unsaturated carbonyls, such as crotonaldehyde, 4-hydroxynonenal, trans-2-hexenal, trans-2,4-hexadienal and their glutathione-conjugates carbonyls (GS-carbonyls) (By similarity).
What are the official names of this protein?
Aldo-keto reductase family 1 member B1, Aldehyde reductase, Aldo-keto reductase family 1 member B3, Aldose reductase, AR.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IML2_VANPO
Sequence: MLRVFGSLTRSRSSSVLSQDDKIKQILKQAHDFEIALQAMDYVLDDRAEEGLALLKKNEAEDGSDQTINVLARGVIEFLEATLGFEAEEMKKASETLAKAENLSLKSRQYAQKNDLKSSSLYAPGTVYAVTYTESCLLHALLMIFSESYVETAKALLKLRKAYYMLQEIFEEMKKVKQTNGNMSIYKSETNHSEASVDSSNASFSSVDIPYELTREESNNSLYQESAEKVQKMRVRRLTGSHIGNTPAIDRLRSELGLDGPKVTTEENSNEYSALSENMDFSQATIDEFIHSGVNLCYGILQVVLSLLPSGIGAVLSVVGFHGSREDGLRLVWRATKQRNIHGCIGLLGLMFYYDGPFQFTDADFDIPVPENELKKTKSSSTYEEGDLDGPTLLHPGKILEDALLQSRALFPHSALWLLNEATMLSGQGRLRDSVKLMDSIEADKIEMRQVKSLLIFNRALTLVHLHEYERAADDFLSLLDISSWSHSLYHYFAGSCYLEIYRMHQLGVRKSDRPEHFKQRATDLIFGAPNLLTRKSFNARPLPLDRFMLRKVDQFKATQKRLKLSDPLDAIATSPVHELQYFYNGYNRMGKQDLELANIMLTEYHNPAIDAKEPNQEMIKDFLVSLTYRRLDRAEEGCELLDRNVLPKIFTMVNGKVKYFKKTEDPWLYPSALYERSLFSWKLKHMDGLEESKEWLTRAQGYADDYELSTRVEMKIKAAIDRVDESL
What is the function of this protein?
Inclusion body (IB) resident protein that interacts strongly with lipid droplet (LD) proteins.  Involved in LD-mediated IB clearing after protein folding stress, probably by enabling access to the IBs of an LD-stored soluble sterol derivative that acts as chaperone in inclusion clearing.
What are the official names of this protein?
Inclusion body clearance protein IML2.
What is the protein family that this protein belongs to?
Belongs to the IML2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localized exclusively in cytoplasmic inclusion bodies under protein folding stress conditions.
Protein: CISY_RICJA
Sequence: DSEFAELKIRGKIFKLPILKASIGEDVIDISRVSAEADCFTYDPGFMSTASCQSTVTYIDGDKGILRHRGYDIKDLAEKSDFLEVAYLLIYGELPSGEQYNNFTKQVAHHSLVNDRLHYLFQTFCSSSHPMAIMLAAVGSLSAFYPDLLNFKEADYELTAIRMIAKIPTIAAMSYKYSIGQPFIYPDNSLDFTENFLHMMFATPYTKYTVNPIIKNALNKIFILHADHEQNASTSTVRIAGSSGANPFACISTGIASLWGPAHGGANEAVINMLKEIGSSEYIPKYIAKAKDKNDPFRLMGFGHRVYKNYDPRAAVLKETCKEVLKELGQLDNNPLLQIAIELEAIALKDEYFIERKLYPNVDFYSGIIYKAMGIPSQMFTVLFAIARTVGWMAQWKEMHEDPEQKISRPR
What are the official names of this protein?
Citrate synthase.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.