PharMolix/UniProtQA huggingface dataset:
Protein: SECA_ENTFA
Sequence: MANFLKKMIENDKKELRRLEKIADKIDAHASAMEQLSDEQLREKTDEFKARYQKGETLDELLPEAFAVVREAAKRVLGLFPYRVQLMGGIVLHDGNIPEMRTGEGKTLTATMPVYLNALSGEGVHVVTVNEYLATRDSNEMGELYNFLGLSVGLNINSKSSDEKREAYNCDITYSTNNELGFDYLRDNMVVYRSQMVQRPLNYAIVDEVDSILIDEARTPLIISGQAEKSTALYTRADNFVKRLKEDEDYKIDIQSKTIGLTEAGIEKAEQTFGLDNLYDIENTALTHHLDQALRANYIMLLDIDYVVQDNKVLIVDQFTGRIMDGRRYSDGLHQAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVIQIPTNRPIIRDDRPDLLYPTLESKFNAVVEDIKERYHKGQPVLVGTVAVETSELLSDKLNAAKIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVLELGGLAVIGTERHESRRIDNQLRGRAGRQGDPGVSQFYLSLEDDLMKRFGSERIKTFLERMNVQEEDAVIQSKMFTRQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYAQRQEVIMEENDLSDVLMGMVKRTIGRVVDSHTQLEKEEWNLDGIVDFAASTLVHEDTISKKDLENKSAEEIKDYLVARAQEVFEEKSQQLNGQEQLLEFEKVVILRVVDTKWTDHIDAMDQLRQSVGLRAYGQNNPLVEYQTEGYSMYNNMVGSIEYEVTRLFMKSEIRQNVQREQVAQGQAEHPETEQDAAAQSNTSAKRQPVRVDKKVGRNDLCPCGSGKKFKNCHGRNA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: FSCN3_HUMAN
Sequence: MDETEWIHRHPKAEDLRVGLISWAGTYLTFEACKNTVTATAKSLGRRQTWEILVSNEHETQAVVRLKSVQGLYLLCECDGTVCYGRPRTSHHGCFLLRFHRNSKWTLQCLISGRYLESNGKDVFCTSHVLSAYHMWTPRPALHVHVILYSPIHRCYARADPTMGRIWVDAAVPCLEECGFLLHFRDGCYHLETSTHHFLSHVDRLFSQPSSQTAFHMQVRPGGLVALCDGEGGMLYPQGTHLLLGMGCNPMRGEEWFILQHCPTWVSLRSKTGRFISVIYDGEVRAASERLNRMSLFQFECDSESPTVQLRSANGYYLSQRRHRAVMADGHPLESDTFFRMHWNCGRIILQSCRGRFLGIAPNSLLMANVILPGPNEEFGILFANRSFLVLRGRYGYVGSSSGHDLIQCNQDQPDRIHLLPCRPGIYHFQAQGGSFWSITSFGTFRPWGKFALNFCIELQGSNLLTVLAPNGFYMRADQSGTLLADSEDITRECIWEF
What is the function of this protein?
Acts as an actin bundling protein.
What are the official names of this protein?
Fascin-3, Testis fascin.
What is the protein family that this protein belongs to?
Belongs to the fascin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: TYSY_SHEB5
Sequence: MKQYLDLMKHILAEGVDKSDRTGTGTRSVFGYQMRFDLSKGFPLVSTKKCHMRSIIHELLWFLKGETNVAYLRENKVSIWDEWADENGDLGPVYGAQWRSWPTQSGDAIDQISQVIAQIKSQPDSRRLIVSAWNVGELDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLTMMVAQQCDLALGDFVWTGGDTHLYSNHMEQTALQLSREPMPLPTMTILRRPESIFDYQFDDFELTNYAPHPHIKAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BRNQL_STAA3
Sequence: MNKNTWVIGFTLFAMFFGAGNLIFPPNLGLDSGQFFWPAILAFVLTGIGLPLLGVIVGALDKEGYIGALNKISPKFSILFLIIIYLTIGPLFAIPRTASTSFEMTITPIIHSNSSIALFIFTIIYFIVVLYICLNPSKLIDRIGSLLTPLLLITILAMIIKGYLDFSGNSAGKGNEALYHSNFSSFAEGFTQGYLTMDAIAAIAFSMIVVNAVKLTGITKTNQIFKQTLTAGLIAAVALIFIYISLGYIGNHMPVSDMTLDQLKSKDRNIGTYLLTTMASTGFGSFGKYLLGIIVALACLTTACGLIVAVSEYFHRIVPKVSYKAFVLVFILMSFIIANQGLNAVISMSIPVLSIVYPVAITVVLLILIAKFIPTKRISQQIPVIIVFILSIFSVISKLGWLKINFIESLPLRAYSLEWFPVAIIATILGYLVGIFVKQDPIKYQQE
What is the function of this protein?
Component of the transport system for branched-chain amino acids (leucine, isoleucine and valine), which is coupled to a proton motive force (Potential).  Contributes to NaCl tolerance (By similarity).
What are the official names of this protein?
Putative branched-chain amino acid carrier protein SAUSA300_1300.
What is the protein family that this protein belongs to?
Belongs to the branched chain amino acid transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RLMN_POLNA
Sequence: MTTNLLDFDLEGLAAFCEQLGQKRFRATQLFRWIHQKGASDFEQMTDLAKSLREKLAVSAHIQGLNVVSRHESADGTIKWLFDVGAGDVIETVFIPETDRGTLCISSQAGCAVGCRFCSTGHQGFSRNLTTGEIISQLWFAEHFLRKHLGRNERVISNVVMMGMGEPLQNYSQLLPALKVMLNDHGYGLSRRRVTVSTSGVVPMIDRLAKDCPVALAVSLHAPQDALRSNLVPLNKKYPIAELLEACTRYQSAAPRDFITFEYCMLDGVNDQPEHARQLVALMKTHAANGLSCKFNLIPFNPFPASGLLRSDMPQVMAFAKILMDAGIITTVRKTRGDDIDAACGQLAGDVQDRTSVDQRMAAQRQGMLGGIKVVVVNGDTA
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CB21_MAIZE
Sequence: MAASTMAISSTAMAGTPIKVGSFGEGRITMRKTVGKPKVAASGSPWYGPDRVKYLGPFSGEPPSYLTGEFPGDYGWDTAGLSADPETFAKNRELEVIHSRWAMLGALGCVFPELLSRNGVKFGEAVWFKAGSQIFSEGGLDYLGNPSLIHAQSILAIWACQVVLMGAVEGYRIAGGPLGEVVDPLYPGGSFDPLGLADDPEAFAELKVKELKNGRLAMFSMFGFFVQAIVTGKGPLENLADHIADPVNNNAWAYATNFVPGN
What is the function of this protein?
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.
What are the official names of this protein?
Chlorophyll a-b binding protein 1, chloroplastic, LHCII type I CAB-1, LHCP.
What is the protein family that this protein belongs to?
Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein.
Protein: PROF4_HUMAN
Sequence: MSHLQSLLLDTLLGTKHVDSAALIKIQERSLCVASPGFNVTPSDVRTLVNGFAKNPLQARREGLYFKGKDYRCVRADEYSLYAKNENTGVVVVKTHLYLLVATYTEGMYPSICVEATESLGDYLRKKGS
What is the function of this protein?
Involved in male fertility.  Required for manchette development and acrosome biogenesis during spermiogenesis (By similarity).  Binds in vitro to phospholipids, including phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), phosphatidylinositol 4-phosphate (PtdIns(4)P) and phosphatidic acid (PA) (PubMed:19419568).  Contrary to other profilin family members, does not bind to actin in vitro (PubMed:19419568).
What are the official names of this protein?
Profilin-4, Profilin IV.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: CLPX_SODGM
Sequence: MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRERSALPTPHEIRHHLDDYVIGQEKAKKVLAVAVYNHYKRLRNGDTNNGIELGKSNILLIGPTGSGKTLLAETLARFLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVIEQRTETNRGIGFSATVKGSSEKVTKGELLAQVEPEDLIKFGLIPEFIGRLPVVATLNELSEEALIQILHEPKNALTKQYQALFNLEGVELEFRDEALTAIAKKAMARKTGARGLRSIVEGALLETMYELPSQDSVEKVVIDEAVIAGQSEPLLIYGKHEAQQASGE
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: RPOC_MARN8
Sequence: MKDLLNLLKSQNQSKEFDAIRIGLASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCAKIFGPIKDYECLCGKYKRLKHRGVICEKCGVEVALASVRRERMGHIELASPVAHIWFLKSLPSRIGLMLDMTLRDIERVLYFESFIVIDPGMTTLEKGQLLNDEQYYEALEEFGDEFDARMGAEAVKQLLEDIDLQAEVDALREEIPQTNSETKIKKFSKRLKILEAFLYSGNKPGDMVMTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELNAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGTNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVIVVGPYLRLHQCGLPKKMALELFKPFIFSKLEHRGLATTIKAAKKMVEREEGVVWDILDEVIREHPILLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNVLSPANGEPIIVPSQDVVLGLYYMTRERHAALGEGMVFADVKEAHRAYGAGQVDLQAKVKVRVKEVAVDEDGNRTESFRIVDTTVGRALLYDIVPDGLPFEIVNKPMVKKAISNLINTCYRDAGLKDTVIFADQLMYMGYHYATRSGISIGFNDFEIPPEKYELVDAASDEVKDIENQYASGLLTQGEKYNKVIDIWSRANDKVSKAMMERLSKEQVIGPDGQPVKGEDGEDLMQESFNSVYMMADSGARGSAAQIRQLSGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVSQDLVVTEEDCGTDEGLLMTPHIEGGDVVVPLGDRVLGRVTARDVFTPTDKDNAVVPAGTLLDEKTVEMVERAGVDEIWVRSAITCETRHGICSKCYGRDLARGHQVNVGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRASAVDNIQVKHGGTVRLHNLKSIEKTDGSLVVVSRSSALAIADEQGREREWYKLPYGAVLSVKNGDQVEAGVVVAKWDPHTHPIIAEAKGTAKFVNMEEGITVRTQADELTGLSTMEVIDPKERPAAGKDIRPAIQLVDDSGEEVELPGGGTAIFFLPANALVTMANGAKIELGDVVARIPQESSKTRDITGGLPRVADLFEARRPKESAILAEISGVVSFGKETKGKKRLVITPKDDDAYEVLIPKHRQLNVFEGETVEKGEVISDGPSNPHDILRLLGVVELAKYITNEIQDVYRLQGVVINDKHIEVIVRQMLRKVEITDPGDTTLLSGDQVEITQVMEENEKANAADKEPARFERLLLGITKASLATESFISAASFQETTRVLTEGAVTGKRDYLRGLKENVVVGRLIPAGTGLAYHNERRRKRDLEEQGVTAADVEEALSAELNRES
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: OR59A_DROME
Sequence: MAEVRVDSLEFFKSHWTAWRYLGVAHFRVENWKNLYVFYSIVSNLLVTLCYPVHLGISLFRNRTITEDILNLTTFATCTACSVKCLLYAYNIKDVLEMERLLRLLDERVVGPEQRSIYGQVRVQLRNVLYVFIGIYMPCALFAELSFLFKEERGLMYPAWFPFDWLHSTRNYYIANAYQIVGISFQLLQNYVSDCFPAVVLCLISSHIKMLYNRFEEVGLDPARDAEKDLEACITDHKHILEWAGGSLVRVLFTFQLFSRLFRRIEAFISLPMLIQFTVTALNVCIGLAALVFFVSEPMARMYFIFYSLAMPLQIFPSCFFGTDNEYWFGRLHYAAFSCNWHTQNRSFKRKMMLFVEQSLKKSTAVAGGMMRIHLDTFFSTLKGAYSLFTIIIRMRK
What is the function of this protein?
Odorant receptor which mediates acceptance or avoidance behavior, depending on its substrates.  The odorant receptor repertoire encodes a large collection of odor stimuli that vary widely in identity, intensity, and duration.  May form a complex with Orco to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability.  Involved in the behavioral responses to ethyl acetate, anisole, hexanoic acid, and pyrazines.
What are the official names of this protein?
Odorant receptor 59a.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Heteromeric odorant receptor channel (TC 1.A.69) family. Or2a subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KPRS2_STRA3
Sequence: MAEQYADKQIKLFSLTANREIAEKISQASGIPLGKMSSRQFSDGEIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMIDACKRASANTVNIVVPYFGYSRQDRIAASREPITAKLVANMLVKAGVDRVLTLDLHAVQVQGFFDIPVDNLFTVPLFAEHYNQLGLSGEDVVVVSPKNSGIKRARSLAEYLDSPIAIIDYAQDDSEREEGYIIGEVEGKKAIIIDDILNTGKTFAEAAKILERGGATEIYAVASHGLFAGGAADILESAPIREIIVTDSVLSKERIPSNIKYLTASHLIADAIIRIHERKPLSPLFSYRSDKKD
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Putative ribose-phosphate pyrophosphokinase 2, RPPK 2, 5-phospho-D-ribosyl alpha-1-diphosphate synthase 2, Phosphoribosyl diphosphate synthase 2, Phosphoribosyl pyrophosphate synthase 2, P-Rib-PP synthase 2, PRPP synthase 2, PRPPase 2.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_PSECP
Sequence: MAHKKGASSTRNGRDSNAQYLGVKRFGGQVVSAGEIIVRQRGTHFHPGAGVGRGGDDTLFALTPGAVEFGTRRGRRVVNIVAAAAAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: PERB_ECO57
Sequence: MNLYGIFGAGSYGRETIPILNQQIKQECGSDYALVFVDDVLAGKKVNGFEVLSTNCFLKAPYLKKYFNVAIANDKIRQRVSESILLHGVEPITIKHPNSVVYDHTMIGSGAIISPFVTISTNTHIGRFFHANIYSYVAHDCQIGDYVTFAPGAKCNGYVVIEDNAYIGSGAVIKQGVPNRPLIIGAGAIIGMGAVVTKSVPAGITVCGNPAREMKRSPTSI
What is the function of this protein?
Catalyzes the transfer of an acetyl residue from acetyl-CoA onto GDP-perosamine to form GDP-N-acetyl-perosamine.
What are the official names of this protein?
GDP-perosamine N-acetyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: IF2_NEIG1
Sequence: MSNTTVEQFAAELKRPVEDLLKQLKEAGVSKNSGSDSLTLDDKQLLNAYLTKKNGSNGGTISIRRTKTEVSTVDGVKVETRKRGRTVNIPSAEELAAQVKAAQTQAAPVQPEQTAEDAVKARAEAAARAEARAKAEAEAAKLKAAKAGNKAKPAAQKPTEAKAETAPVAAETKPAEPKEKAVKPKHERNGKGKDAKKPAKPAAPAVPQPVVSAEEQAQRDEEARRAAALRAHQEALLKEKQERQARREAMKQQAEQQAKAAQEAKTGRQRPAKPAEKPQAAAPAVENKPVNPAKAKKEDRRNRDDEGQGRNAKGKGAKGGRDRNNARNGGDERVRGGKKGKKLKLEPNQHAFQAPTEPVVHEVLVPETITVADLAHKMAVKGVEMVKALMKKGMMVTINQSIDQDTALIVVKKLGHIGKPAAADDPEAFLGEGAEAEEAEALPRPPVVTVMGHVDHGKTSLLDYIRRAKVVQGEAGGITQHIGAYHVKTPRGVITFLDTPGHEAFTAMRARGAKATDIVILVVAADDGVMPQTIEAIAHAKAAGVPIVVAVNKIDKDTANPERIRQELTQHEVIPDDWGGTVQFIDVSAKKGTNIDALLEAVLLEAEVLELTAPVDAPAKGIIVEARLDKGRGAVATLLVQNGTLKKGDMLLAGTAFGKIRAMVDENGKSITEAGPSIPVEILGLSDVPNAGEDAMVLADEKKAREIALFRQGKYRDVRLAKQQAAKLENMFNNMGETQAQSLSVIIKADVQGSYEALAGSLKKLSADEVKVNVLHSGVGGITESDVNLAIASGAFIIGFNVRADASSRKLAENENVEIRYYNIIYDAIDDVKAAMSGMLSPEKKEQVTGTVEIRQVISVSKVGNIAGCMVTDGVVKRDSHIRLIRNNVVIHTGELASLKRYKDDVKEVRMGFECGLMLKGYNEIMEGDQLECFDIVEVARTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEPD_MYCTU
Sequence: MAKLARVVGLVQEEQPSDMTNHPRYSPPPQQPGTPGYAQGQQQTYSQQFDWRYPPSPPPQPTQYRQPYEALGGTRPGLIPGVIPTMTPPPGMVRQRPRAGMLAIGAVTIAVVSAGIGGAAASLVGFNRAPAGPSGGPVAASAAPSIPAANMPPGSVEQVAAKVVPSVVMLETDLGRQSEEGSGIILSAEGLILTNNHVIAAAAKPPLGSPPPKTTVTFSDGRTAPFTVVGADPTSDIAVVRVQGVSGLTPISLGSSSDLRVGQPVLAIGSPLGLEGTVTTGIVSALNRPVSTTGEAGNQNTVLDAIQTDAAINPGNSGGALVNMNAQLVGVNSAIATLGADSADAQSGSIGLGFAIPVDQAKRIADELISTGKASHASLGVQVTNDKDTLGAKIVEVVAGGAAANAGVPKGVVVTKVDDRPINSADALVAAVRSKAPGATVALTFQDPSGGSRTVQVTLGKAEQ
What is the function of this protein?
Required for virulence (PubMed:18479146).  Acts both as a protease, which degrades and/or refolds damaged substrate targets, and as a chaperone (PubMed:18479146, PubMed:20061478).  Plays an important role in the stress response network mediated through the two-component regulatory system MprAB and SigE signaling networks (PubMed:20061478).  May utilize its PDZ domain to recognize and process misfolded proteins at the cell membrane, leading to activation of the MprAB and SigE signaling pathways and subsequent establishment of a positive feedback loop that facilitates bacterial adaptation (PubMed:20061478).  Interacts with and potentially cleaves several proteins, including the 35 kDa antigen PspA (PubMed:21445360).  Proteolytic cleavage of PspA may help to maintain cell envelope homeostasis in Mycobacterium and regulate specific stress response pathways during periods of extracytoplasmic stress (PubMed:21445360).  In vitro, exhibits proteolytic activity against the artificial substrate beta-casein (PubMed:18479146, PubMed:20061478).
What are the official names of this protein?
Serine protease PepD, HtrA-like serine protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1C family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein. Secreted, cell wall. Secreted. Note=Traffics from the cytoplasm through the cell membrane to the cell wall where it is autoprocessed and eventually secreted into the culture filtrate protein.
Protein: RLK5_ARATH
Sequence: MLYCLILLLCLSSTYLPSLSLNQDATILRQAKLGLSDPAQSLSSWSDNNDVTPCKWLGVSCDATSNVVSVDLSSFMLVGPFPSILCHLPSLHSLSLYNNSINGSLSADDFDTCHNLISLDLSENLLVGSIPKSLPFNLPNLKFLEISGNNLSDTIPSSFGEFRKLESLNLAGNFLSGTIPASLGNVTTLKELKLAYNLFSPSQIPSQLGNLTELQVLWLAGCNLVGPIPPSLSRLTSLVNLDLTFNQLTGSIPSWITQLKTVEQIELFNNSFSGELPESMGNMTTLKRFDASMNKLTGKIPDNLNLLNLESLNLFENMLEGPLPESITRSKTLSELKLFNNRLTGVLPSQLGANSPLQYVDLSYNRFSGEIPANVCGEGKLEYLILIDNSFSGEISNNLGKCKSLTRVRLSNNKLSGQIPHGFWGLPRLSLLELSDNSFTGSIPKTIIGAKNLSNLRISKNRFSGSIPNEIGSLNGIIEISGAENDFSGEIPESLVKLKQLSRLDLSKNQLSGEIPRELRGWKNLNELNLANNHLSGEIPKEVGILPVLNYLDLSSNQFSGEIPLELQNLKLNVLNLSYNHLSGKIPPLYANKIYAHDFIGNPGLCVDLDGLCRKITRSKNIGYVWILLTIFLLAGLVFVVGIVMFIAKCRKLRALKSSTLAASKWRSFHKLHFSEHEIADCLDEKNVIGFGSSGKVYKVELRGGEVVAVKKLNKSVKGGDDEYSSDSLNRDVFAAEVETLGTIRHKSIVRLWCCCSSGDCKLLVYEYMPNGSLADVLHGDRKGGVVLGWPERLRIALDAAEGLSYLHHDCVPPIVHRDVKSSNILLDSDYGAKVADFGIAKVGQMSGSKTPEAMSGIAGSCGYIAPEYVYTLRVNEKSDIYSFGVVLLELVTGKQPTDSELGDKDMAKWVCTALDKCGLEPVIDPKLDLKFKEEISKVIHIGLLCTSPLPLNRPSMRKVVIMLQEVSGAVPCSSPNTSKRSKTGGKLSPYYTEDLNSV
What is the function of this protein?
Receptor with a dual specificity kinase activity acting on both serine/threonine- and tyrosine-containing substrates that controls floral organ abscission.  May interact with the 'INFLORESCENCE DEFICIENT IN ABSCISSION' (IDA) ligands family.
What are the official names of this protein?
Receptor-like protein kinase 5, Protein HAESA.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: TM208_XENLA
Sequence: MAPKGKVGTKGKKQIYEENKETLSFYLRIILGATVLCGAINLGVFYSSSNFWTWATLVFSGIVYAGAYRSMRSMAQASFSEDGSLLDGGIDLNMEQGMAEHIKDIVLLTAIVQVLSCFSLYFWYFWLLAPGRALYLLWVNVLGPWFTADNSSTVPQEQNEKRQRRQERRQMKRF
What is the function of this protein?
May function as a negative regulator of endoplasmic reticulum-stress induced autophagy.
What are the official names of this protein?
Transmembrane protein 208.
What is the protein family that this protein belongs to?
Belongs to the TMEM208 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MAND_XANOB
Sequence: MSQPSDSTAPLQGSARDREIVEARVIVTCPGRNFVTLKIRTRSGITGVGDATLNGRELAVAAYLQEHLVPNLIGRDAGRIEDIWQFFYRGAYWRRGPVTMSAIAAVDVALWDILGKMAGMPLYQLLGGRSREGALVYGHANGRDIAETSDEVGRFREMGFIAIRAQCGVPGIKKTYGISVGGKPYEPAESELPTETVWSTPRYLGVVPRLFEQLRADHGDEIELLHDAHHRLTPIEAARLGRDLEPYRLFWLEDATPAENQRAFEIIRQHTVTPLAVGEVFNSIWDCKHLIEQQLIDYIRTTIVHAGGLTHVRRLADFAALHQVRTGFHGATDLSPVCMGAALHFDTWVPNFGIQEYMFHSDEANAVFPHDYQFRAGRLHCGETPGHGVDIDEALAARYPYTPKQLPILRLEDGTMGDW
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.  Has no detectable activity with a panel of 70 other acid sugars (in vitro).
What are the official names of this protein?
D-mannonate dehydratase, ManD.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
Protein: IF61_TRYCC
Sequence: MTLRTRFESSDDVGVFSRLTNAYCLVTAGGSQNFYSVFEQELANHIPVVYTSIGGSRVIGRLTCGNRHGLVVPSIATDQELQHLRNSLPDSVKVQRVEERLNALGNCVVCNDHVALIHTDLSRETEEILRDTLQVQTFRTSIAENALVGSYAVVNNKGCMVHPKTPAQDMDEIASLLQVPVVAGTINRGNAAIGSGLVVNDWAAFCGLNTTATEITVVERIFQLRRDLGGDEPNLLQQLRDTLVDELA
What is the function of this protein?
Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm.  May also be involved in ribosome biogenesis.
What are the official names of this protein?
Eukaryotic translation initiation factor 6, eIF-6.
What is the protein family that this protein belongs to?
Belongs to the eIF-6 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Note=Shuttles between cytoplasm and nucleus/nucleolus.
Protein: MNME_PROMT
Sequence: MNSFSPTEDTIAAIATAVSPGQGSIAAIRISGSSAIETSKNIVDVPGIQDWSTHKVLYGHVTEENRKKYIDEVLILVMKGPRSFTGEDVVEIHCHGGIIPVQKILERILAFPSVRRAEPGEFSQRAVLNGRLSLTQAESISELVSARSRKAAELAINGIEGNIQTTIQSIRKRLIEQLTEIEARIDFEEDLPLLDEKHVKNEIVAIKKDLNELIDNAKRGSWVRSGLKVALTGKPNVGKSSLMNRLSKQEKAIVTDLPGTTRDILESEIILEGIPVTFIDTAGLRDTKDIIEKIGISRTKKTLIHADLIILIFDYSSGWTNEDESILKQLPINIPLLIVGNKSDLTNDQSFEKVPKYILKKENLVIISAKTGNGEDDLINYLLKKCGSSQTHGLDIALNERQLDLAKSTMKSLENINKVFDEKLPWDFWTIDLRQAINYLGELTGEDLTESLLDNIFSKFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1082_HAEIN
Sequence: MELQKIEQILKDTLNIAEVYAQGENAHFGVIVVSDEIAALSRVKQQQTIYAPLMPYFSTGEIHALTIKTYTVEKWKRDRALNQFN
What are the official names of this protein?
Uncharacterized protein HI_1082.
What is the protein family that this protein belongs to?
Belongs to the BolA/IbaG family.
Protein: TACAN_XENTR
Sequence: MNSPALQDCVRDWGELQENYQDIQETHRLYKQKLEELAKLQTRCSGTIARQKKKLKELSVELKKYKSSVKNVEEEEEQISVLNNQIRIREKTFFEMESFLPKKNGLYLSLVLGNVNVTLLSKQSKFAYKDEYEKFKLYLTMILMVLSFICRFVLNSRVTDAVFNFLLVWYYCTLTIRESILINNGSRIKGWWVLNHYISTFLSGVMLTWPDGLMYQMFRNQFLSFSMYQSFVQFLQYYYQSGCLYRLRALGERHNMDLTVEGFQSWMWRGLTFLLPFLFFGQFWQLYNAITLFKLARHPECKEWQVIMCGLPFLVHFLGNFFTTLRVVHQKFQKQN
What is the function of this protein?
Ion channel involved in sensing mechanical pain.  Contributes to mechanosensitive currents in nocireceptors and detecting mechanical pain stimuli.  May also be required for efficient adipogenesis.
What are the official names of this protein?
Ion channel TACAN, Transmembrane protein 120A.
What is the protein family that this protein belongs to?
Belongs to the TMEM120 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Nucleus inner membrane; Multi-pass membrane protein.
Protein: Y1026_LACDA
Sequence: MDLRRIMETVNMIDNENLDLRTTTMGISLLDCIDSDSDRACQKIYDKITTKAENLVKVARELETEYGIPIANKRITVTPISLIAAASGDSDYVKYAVTLDKAAKAVGVDLIGGFSALVHKGYQNGDRVLIKSIPQALKETERVCSSVNVGSTRSGINMDAVKEMGQIVIENEKINPLNNGNLVIFCNAVEDNPFMAGGFHGVGESDVALNVGVSGPGVVKTALEKVKGESMDVVAETIKQTAFKVTRMGQLVGQEASKRLGVDFGIVDLSLAPTPAQGDSVANILEEIGLESVGTHGTTAALAMLNDAVKKGGIMACSHVGGLSGAFIPESEDAGMIAAAEKGILTVDKLEAMTAVCSVGLDMIAVPGDTPAETISAMIADEAAIGMINNKTTAVRVIPVPGKEVGDSIEFGGLFGYAPIMPVHKESSAAMINRGGRIPAPVHSFKN
What are the official names of this protein?
UPF0210 protein Ldb1026.
What is the protein family that this protein belongs to?
Belongs to the UPF0210 family.