PharMolix/UniProtQA huggingface dataset:
Protein: DAPB_BUCAI
Sequence: MNKKTRIAITGPIGRMGRMLIKEIQNNKHSHLTVAVVQKKHQLIGQDIGRIIGIGEIGVLISDELNIKKNDFDVLIDFTRPAGTLEYLKYCNKFKKNIVIGTTGFSKEEIDIIKSYSQKIAIIIASNFSIGINLLFQLIKKTTQIIGKDSDINILEYHHRNKIDAPSGTALEIGEVISKVMNWNLNQDSIYYQKGITGIRDAKKIGFSIVRAGNIVGKHTVMFSSYDEEIKITHTASNRMSFARGAIQSALWIHKKNTGLFDMTDVLSL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T1RH_HAEIN
Sequence: MLNENDIEQLTLQRLQSLGWEYRYGKDLPVHEGKFARGDLSGVVFVEQLREAVRKLNPQLPESAVDSVVKSATKSDIGDLVVRNQTFYKLLRDGVRVEYTQNGEQKIEMVRLVDFEHWGNNRFVAVNQLEIRSRKGGKRIPDIIGFVNGLPLVVFELKNPLRESADLLQAFNQFETYKDEIAELFVYNQALIISDGIVARLGSLSADFQRFTPWKVVDEKNKSARLYFDDELQSLLNGLMQPEDLLDYIRYFVLFERDSVGKTIKKIAAYHQYYGVNEAVDSTIWATSEKGDRRIGVMWHTQGSGKSISMLFYAGKLLAQPELKNPTIVVVTDRNDLDGQLFQTFSSGKDLIKQTPQQVEDRDQLRQLLAQNEVGGVFFTTIQKFALNEEESRFPILNERNNIIVISDEAHRSQYGFTQKLHNGKFQTGYARHLRDALPNASFIGFTGTPISLEDKDTQDVFGRYVSIYDLQDAVEDGATVPIVYDDARQIRLNKKDHDALFAEIDALLEEEPSTSLRLREKLLGSQERLIELAADFVQHFAKRNEVVDSKAMMVVSSRQICVDLYNQIIALHPEWHSDNINEGAIKIVMTGSASDTPEMQKHIYSKQEKQTLERRFKDPNDPLKVVIVRDMWLTGFDAPCCNTMYLDKPMKGHNLMQAIARVNRVFANKSRENGGLIVDYVGLAKELRAATQQYTNSTGKGQLAEDVQSVFFKMKEQLEFIRTLFATPIEGKTFDVQAALEKDNPNDLLMAIRFAANHILSLDQLSFDGKAHEQHWFNKKETEPRKKAFLKTAGLVKKGYMLCGTLAEVEPYNQEIAFYDAVRAILTKREQKGTGTNERQILLKKLVNQTVYSEGVIDLFDLLEKPQPQISLLSEEFLQTVKNSPTKNLWVSAMERYLASEIKVKSGTNLTLQKDFERRLKEALNQYHNHNLTVVEILDELFKMSQDFQERLALGKKLGLTKEELAFYEALSQNQSAKDLMGDEVLSKLAKEITETLRKSVTIDWQYKEAVRARIRLLVRRALQKYKYPPDKQEEAVTYVIKQAEEIAEDLTGL
What is the function of this protein?
The restriction (R) subunit of a type I restriction enzyme that recognizes 5'-RAACN(5)TAG-3' and cleaves a random distance away.  Subunit R is required for both nuclease and ATPase activities, but not for modification.  After locating a non-methylated recognition site, the enzyme complex serves as a molecular motor that translocates DNA in an ATP-dependent manner until a collision occurs that triggers cleavage.
What are the official names of this protein?
Type I restriction enzyme HindI endonuclease subunit, HindI, R protein, Type I restriction enzyme HindVIIP endonuclease subunit.
What is the protein family that this protein belongs to?
Belongs to the HsdR family.
Protein: PAPS4_ARATH
Sequence: MMVGTQNLGGSLPPLNSPKSYGITKPLSLAGPSSADIKRNVELEKYLVDEGLYESKDDTMRREEVLGRIDQIVKHWVKQLTQQRGYTDQMVEDANAVIFTFGSYRLGVHGPGADIDTLCVGPSYVNREEDFFIILHDILAEMEEVTELHPVPDAHVPVMKFKFQGIPIDLLYASISLLVVPQDLDISSSSVLCEVDEPTVRSLNGCRVADQILKLVPNFEHFRTTLRCLKYWAKKRGVYSNVTGFLGGVNWALLVARVCQLYPNAIPSMLVSRFFRVYTQWRWPNPVMLCAIEEDELGFPVWDRRKNHRDRYHLMPIITPAYPCMNSSYNVSQSTLRVMTEQFQFGNNILQEIELNKQHWSSLFEQYMFFEAYKNYLQVDIVAADAEDLLAWKGWVESRFRQLTLKIERDTNGMLMCHPQPNEYVDTARQFLHCAFFMGLQRAEGVGGQECQQFDIRGTVDEFRQEVNMYMFWKPGMDVFVSHVRRRQLPPFVFPNGYRRPRQSRHQNLPGGKSGEDGSVSHSGSVVERHAKRKNDSEMMDVRPEKPEKRASLSPQSLDIVSPENSAITTGWTPPVCNLRRPPSEEIEADNLNTECTELTDLARNECNSGSEQVLEVDSMAVVQECSDPAEPLGKCVTPDSVDVVACVSGQEENLDRNLRSVSISGTDSPLLPSRSCGQNRDYEGFGFPAANSDPMGKKNLYSQSGMSEDLQSNSLVSGMEKSEDRARSESFQKSQIRLLT
What is the function of this protein?
Essential protein (PubMed:19956626).  Polymerase that creates the 3'-poly(A) tail of mRNA's (PubMed:15297145).  Also required for the endoribonucleolytic cleavage reaction at some polyadenylation sites.  May acquire specificity through interaction with a cleavage and polyadenylation specificity factor (CPSF) at its C-terminus (By similarity).
What are the official names of this protein?
Nuclear poly(A) polymerase 4, AtPAP(IV), PAP(IV), Poly(A) polymerase IV, nPAP, Polynucleotide adenylyltransferase 4.
What is the protein family that this protein belongs to?
Belongs to the poly(A) polymerase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EFGM_DROME
Sequence: MSLITRLLTGNNTLRLRALKSLGKAGYSSHAKFSEHKPIERIRNIGISAHIDSGKTTLTERILFYTGRIAEMHEVRGKDNVGATMDSMELERQRGITIQSAATYTLWKDTNINIIDTPGHVDFTVEVERALRVLDGAVLVLCAVGGVQSQTLTVNRQMKRYNVPCLAFINKLDRLGSNPYRVLSQMRSKMNHNAAFIQLPIGVESNCKGIVDLVREKAIYFEGEHGMDIRLDEIPQDMRVESLERRQELIEHLSNADETLGELFLEEKPFTEDDIKAALRRTCINRTFTPVLVGTALKNKGVQPLLDAVLDYLPNPGEVENLGFIEKEGQDPEKVVLNPARDGKDPFVGLAFKLEAGRFGQLTYLRCYQGVLRKGDNIFNARTNKKVRIARLVRLHSNQMEDVNEVYAGDIFALFGVDCASGDTFTTNPKNNLSMESIFVPEPVVSMAIKPNNTKDRDNFSKAIARFTKEDPTFHFFFDNDVKETLVSGMGELHLEIYAQRMEREYGCPVTLGKPKVAFRETLVGPCEFDYLHKKQSGGSGQYARIIGVMEPLPPNQNTLLEFVDETVGTNVPKQFVPGVEKGYREMAEKGMLSGHKLSGIRFRLQDGGHHIVDSSELAFMLAAHGAIKEVFQNGSWQILEPIMLVEVTAPEEFQGAVMGHLSKRHGIITGTEGTEGWFTVYAEVPLNDMFGYAGELRSSTQGKGEFTMEYSRYSPCLPDVQDQIVRQYQESQGLAQPDKKKKKN
What is the function of this protein?
Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).  Essential during development as it acts as a retrograde signal from mitochondria to the nucleus to slow down cell proliferation if mitochondrial energy output is low.
What are the official names of this protein?
Elongation factor G, mitochondrial, EF-Gmt, Elongation factor G 1, mitochondrial, mEF-G 1, Elongation factor G1, dEF-G1, Protein iconoclast.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MS18A_RAT
Sequence: MAGTFSLEPCSTSSSCNHQGKRSESSLLEKRLSEDSSRHWRLQKWASMSSADASRTLLERREEKAAAAENPLVFLCTRCRRPLGDSLTWVASQEDTNCILLRSVSSNVSVDKEQKLSKCRDEDGCILETLYCSGCSLSLGYVYRCTPKNLDYKRNLFCLSVEAVESYTLGSSEQQIVSEEEFFNLESRVEIEKSIKQMEDVLTVMQAKLWEVESKLSKAGRYS
What is the function of this protein?
Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
What are the official names of this protein?
Protein Mis18-alpha.
What is the protein family that this protein belongs to?
Belongs to the mis18 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Chromosome, centromere. Note=Associated with centromeres in interphase cells, from late anaphase to the G1 phase. Not detected on centromeres during earlier phases of mitosis. Associated with chromatin.
Protein: RS182_ROSS1
Sequence: MTEDQARRSGGVGRRRFGARRKVCMFCADQIRVVDYKDVKRLQRCMSERGKILPRRRTGVCARHQRSLTVAIKRARHMALLPFVAAHIRS
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: CH10_THEBR
Sequence: MRLKPLGDRVVVKVIQAEEVTKGGVILPGTAKEKPQQGEVVAVGTGEYIDGKKVELEVKVGDRVIFSKYAGTEVKLDGEEYLLLRESDILAIIE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_MESFL
Sequence: MARSLKKGPFVDENLFKKAEVAKDGEVIKTWSRRSTIFPEFIGKTFGVYNGKEFIPVYVTEDMVGHKLGEFAPTRKFGGHGDDKGKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: FGFR3_PLEWA
Sequence: MLVWLCGLCLVTLAGGRSAARLPLTEGRPTADFLPGDASLVEELLFGTGDTIELSCTTPGSSVSVVWFKDGISVDPPTWSHTGQKLLKIINVSYDDSGVYSCKARQSSEVLRNVTVRVTDSPSSGDDEDDDEESESANAPKFTRPEWMEKKLLAVPAANTVRFRCPAAGKPTPSITWLKNGKEFKGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVANKYGTIRETYTLDVLERTPHRPILQAGFRSNKTVVVGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKFGPDGNPYVTVLKTAGVNTSDKELEIQFLRNVTFEDAGEYTCLAGNSIGYSHHSAWLTVLPPAEPVPDVDTSVSILAAAGCVAVVILVVIIIFTYKMKMPSKKTMNTATVHKVSKFPLKRQVSLESNSSMNSNTPLVRITRLSSSDGPMLANVSELELPADPKWELSRSRLTLGKPLGEGCFGQVVMADAVGIEKDKPNKATSVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVLVEYASKGNLREYLRARRPPGMDYSFDTCKLPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTDDNVMKIADFGLARDVHNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHELYMIMRECWHAVPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSVPFEQYSPACPDSHSSCSSGDDSVFAHDLPEEPCLPKHQQYNGVIRT
What is the function of this protein?
Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis.  Plays an essential role in the regulation of chondrocyte differentiation, proliferation and apoptosis, and is required for normal skeleton development.  Regulates both osteogenesis and postnatal bone mineralization by osteoblasts.  Promotes apoptosis in chondrocytes, but can also promote cancer cell proliferation.  Phosphorylates PLCG1, CBL and FRS2.  Ligand binding leads to the activation of several signaling cascades.  Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate.  Phosphorylation of FRS2 triggers recruitment of GRB2, GAB1, PIK3R1 and SOS1, and mediates activation of RAS, MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway (By similarity).
What are the official names of this protein?
Fibroblast growth factor receptor 3, FGFR-3, PFR3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: VNS4_AQRVC
Sequence: MNADRTLSDEQYDWIVAYERHITPHAVLSVRTPAYGRMPPLQIPTFTGPTPTYFVYDGNVEEVSGQLIKDPSDDTLPHHYAATWTCSLFTSRPPSDPAWPRDSVMQYDSNWSPYHRVPMRYFPSFMTLDSDLLGPNDGFWPLLHRCAGFRLRSPWRFPLDVLAAGIGTTVSTIRSLEKAGALNTVEGLLRALGWKYHHLSGLRPQHVEYCMSVWSLSFTRADLDVIDPASWFDGLLRSPIYPDEAPIGLNCEQITTHPFVLLNWIRVQLMDDGC
What are the official names of this protein?
Non-structural protein 4, NS4.
What is the protein family that this protein belongs to?
Belongs to the aquareoviridae NS4 protein family.
Protein: RFCS_PYRHO
Sequence: MHNMEEVREVKVLEKPWVEKYRPQRLDEIVGQEHIVKRLKHYVKTGSMPHLLFAGPPGVGKCLTGDTKVIANGQLFELRELVEKISGGKFGPTPVKGLKVIGIDEDGKLREFEVQYVYKDKTERLIRIRTRLGRELKVTPYHPLLVNRRNGEIKWVKAEELKPGDKLAVPRFLPIVTGEDPLAEWLGYFLGGGYADSKENLIMFTNEDPLLRQRFMELTEKLFSDARIREITHENGTSKVYVNSKKALKLVNSLGNAHIPKECWRGIRSFLRAYFDCNGGVKGNAIVLATASKEMSQEIAYALAGFGIISRIQEYRVIISGSDNVKKFLNEIGFINRNKLEKALKLVKKDDPGHDGLEINYELISYVKDRLRLSFFNDKRSWSYREAKEISWELMKEIYYRLDELEKLKESLSRGILIDWNEVAKRIEEVAEETGIRADELLEYIEGKRKLSFKDYIKIAKVLGIDVEHTIEAMRVFARKYSSYAEIGRRLGTWNSSVKTILESNAVNVEILERIRKIELELIEEILSDEKLKEGIAYLIFLSQNELYWDEITKVEELRGEFIIYDLHVPGYHNFIAGNMPTVVHNTTAALALSRELFGENWRHNFLELNASDERGINVIREKVKEFARTKPIGGASFKIIFLDEADALTQDAQQALRRTMEMFSSNVRFILSCNYSSKIIEPIQSRCAIFRFRPLRDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMRRAINILQAAAALDKKITDENVFMVASRARPEDIREMMLLALKGNFLKAREKLREILLKQGLSGEDVLIQMHKEVFNLPIDEPTKVYLADKIGEYNFRLVEGANEMIQLEALLAQFTLVGKKK
What is the function of this protein?
Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.
What are the official names of this protein?
Replication factor C small subunit, RFC small subunit, Clamp loader small subunit.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family. RfcS subfamily.
Protein: ARD1_UROFA
Sequence: MATQTLPAQMTALYYEKPRDFSIIKADVPLIDHDEVLLKVSMCGVCGTDQHIHEGEFIAKFPLIPGHEVIGTIVLAGNQVENVKVGDRVVCDVSETCHKCFFCQRGTPLFCESFEAHGVTLNGGFAEYAKFRAAKVFPIKNLTDEQATLVEPASCAVHGLDKIRPKPGSECLLIGAGPTGLMLAQLLKLNGAQRVVLAANKGMKMDIARKINAADEYIDLDRKDAANQWAQLKEDNPHGFDVVVEATGVESIVNDSINYVRRGGTLLVYGVYDNAARVTWSPTKIFQDEINIVGSFAQIHCFPRAVAYLESGKIRTDGMVTHVYKIEEYQEALDKMASRQCLKIAVKPN
What is the function of this protein?
D-arabinitol dehydrogenase which mostly produces D-arabinitol in haustoria, the appendages of the parasitic fungus that penetrate the host's tissue and draws nutrients from it.  D-arabinitol accumulation may serve as a carbohydrate storage compound.  D-arabinitol is also capable of quenching reactive oxygen species involved in host plant defense reactions, thus providing protection for the rust fungus during the pathogenic interaction.
What are the official names of this protein?
D-arabinitol dehydrogenase 1, NADP-dependent D-arabitol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cell projection. Note=Localizes in the lumen of haustoria.
Protein: PAP1_ASFWA
Sequence: MSSLLKPDFNVSKYRLIAQKREANAVEIEAALEVVREFIIKKKLILYGGIAIDYALHLKGSSIYPEGERPDFDMFSPNHVEDAYELADILYEKGFKQVGTVRAIHVQTMRVRTDFVWVADLSYMPPNIFDTIPTLTYKNLKIIHPDYQRAGLHLAFCFPFDNPPREDVFSRFKKDLQRYNLIEKYYPIPVVPVKSTYESKTFSIPFKQVAIHGFAAYALLYQTLNELRITCKVPEWKTEFPQPSYSYHKNDKNITLTIDMPRAYPALVLATYNPEGVIKEMGLHLTEICEPYMDYSPPIFKTNDIHFFSTMFKELAISIIQDNLIVVSPQYLLLYFLYGAFATPADKSLFLFYYNATLWILEKADSLLNIIQKQTSPEEFTRFANTSPFVLTTRVLSCSQERCTFSPAYRISLANDVQQSQLPLPKTHFLSNSLPDISTLPYNYYPGKGKEKPTNFSYEKNLLFNIGGKCTPSAM
What is the function of this protein?
Polymerase that creates the 3'-poly(A) tail of mRNAs.
What are the official names of this protein?
Putative poly(A) polymerase catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the poxviridae poly(A) polymerase catalytic subunit family. Highly divergent.
What are the subcellular locations of this protein?
Virion.
Protein: GCSP_PROMT
Sequence: MSKAELKDFTFKSRHIGPTNEDEALMLQHLGYENAEEFISSVIPNEIFDSENNGVSIPDGCDQNKALTEINIISKKNVEHRSLIGLGYHSTVIPPVIQRNVLENPNWYTAYTPYQAEISQGRLEALFNFQTLISELTGLPISNASLLDEATAAAEAISLSLTVRKNKNANKFLVDQEILPQTLDVLKTRCEPLGISLEMFDNNNFEIDKNVFGILIQLPGKNGRIWDPTKIINDAHKCNAIVTIAIDPLAQVLIKPMGEFGADIVVGSAQRFGVPIAFGGPHAAFFATKEIYKRQIPGRIVGQSVDVEGNQALRLALQTREQHIRRDKATSNICTAQVLLAVLSSFYAVHHGPKGLKQIAENVVKYRSNFESILMNLEYPIEKYSAFDSVDVYCSEASEVIQLASEEGYNLRVLPIGSDFENAKGFGVTFDELTCDEEIYKLHQILAQVKGKKTHDLSNFIFENASLIDIPLREKSWLEQSVFNQYQSETDLMRYIHCLVSKDFSLVQGMIPLGSCTMKLNAAAELLPIEWREFSSIHPFAPHTQLTGFHEIINDLENWLSALTGFQGVSLQPNAGSQGEFAGLLVIRSWHQSLGEGHRNICLIPTSAHGTNPASAVMSGFKVVSVKCDEYGNVDLEDLKNKSKIHSKNLAALMVTYPSTHGVFEPNIREMCQVIHQEGGQVYLDGANLNAQVGICRPGSYGIDVCHLNLHKTFSIPHGGGGPGVGPIAVADHLVPYLPGHSIIKCGGQKAISAVSAAPFGSAGILPISWMYIRMMGSDGLRKASSIAILSANYLAKRLDPYYPVLFKDPNGLVAHECILDLRPLKSQLGIEVEDVAKRLMDYGFHAPTISWPVAGTLMVEPTESESLPELDRFCDAMIGIREEIEQIKLGKIDPINNPLKQSPHTLKTVTSDDWDRPYSRKEAAYPLPDQEKYKFWPSVSRINNAYGDRNLICSCPSVQDLEDINSV
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: NUDI_SALEP
Sequence: MRQRTIVCPLIQNDGCYLLCKMADNRGVFPGQWALSGGGVEPGERIEEALRREIREELGEQLILSDITPWTFRDDIRVKTYADGRQEEIYMIYLIFDCVSANRDICINDEFQDYAWVKPEELALYDLNVATRHTLALKGLL
What is the function of this protein?
Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP).
What are the official names of this protein?
Nucleoside triphosphatase NudI, Nucleotide diphosphatase NudI, Pyrimidine deoxynucleoside triphosphate diphosphatase, dCTP diphosphatase, dTTP diphosphatase, dUTP diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudI subfamily.
Protein: O1444_MOUSE
Sequence: MTSMENITEVTEFILLGLTDDPNLQVPLLLIFLFIYLVTLIGNGGMMVIIFSDSHLHTPMYFFLSNLSFVDLGYSSAVAPKMVAALQSGNKVISYNGCAAQFFFFVGFATVECYLLASMAYDRHAAVCRPLHYTTTMTTGVCTILTIGSYTCGFLNASIHAADTFKLSFCGSNKINHFFCDIPPLLALACSSTHISKLVVFFVVGFNVFFTLLVIIISYFFIYIAIQNMKSSEGRKKAFSTCASHLTAVSIFYGTIIFMYLQPSSGQSMDTDKIASVFYTVVIPMLNPLIYSLRNREVKSALWKILNRFYPASFSVSRK
What is the function of this protein?
Potential odorant receptor.
What are the official names of this protein?
Olfactory receptor 1444, Olfactory receptor 202-4.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: METK_PSEA8
Sequence: MSEYSVFTSESVSEGHPDKIADQISDAVLDAIIAKDKYARVACETLVKTGVAIIAGEVTTSAWVDLEELVRKVIIDIGYDSSDVGFDGATCGVLNIIGKQSVDINQGVDRAKPEDQGAGDQGLMFGYASNETDVLMPAPICFSHRLVERQAEARKSGLLPWLRPDAKSQVTCRYEGGKVVGIDAVVLSTQHNPEVSYNDLRDGVMELIIKQVLPAELLHKDTQFHINPTGNFVIGGPVGDCGLTGRKIIVDSYGGMARHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLAERCEIQVSYAIGVAQPTSISINTFGTGKVSDEKIVQLVREHFDLRPYAITKMLDLLHPMYQPTAAYGHFGRHPFELTVDGDTFTAFTWEKTDKAALLRDAAGL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EXBB_MANHA
Sequence: MEQLFQFLEHHTDFVILGLLGLLSVICLWKAIERIMFYSKVDISKYDTLEELDIDLTHNLTTISTIGSNAPYIGLLGTVVGILLTFYHLGQSGGDIDAASIMVNLSLALKATAVGILVAIIAMVFYNGFGRKVEENKLKWLALQSKKPHQAV
What is the function of this protein?
Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.  Protects ExbD from proteolytic degradation and functionally stabilizes TonB (By similarity).
What are the official names of this protein?
Biopolymer transport protein ExbB.
What is the protein family that this protein belongs to?
Belongs to the ExbB/TolQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPF_BUCAP
Sequence: MNLNATILGQALSFILFVWFCMKYIWPPIIFAIETRQKNIEESLISLKKAEEELIIIQKKMNQIIQDSKEKASFIINEANKKKSIILEDAKSIALEESKKIFLRNQLEIDLKVMQVRKNLHKEIVDLSILIAEKIIKDNIQKDQYKYSIKKLIVSLSKDKKLI
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PDXA_SHIBS
Sequence: MVKTQRVVITPGEPAGIGPDLVVQLAQREWPVELVVCADATLLTDRAAMLGLPLTLRPYSPNSPAQPQTAGTLTLLPVALRESVTAGQLAIENGHYVVETLARACDGCLNGEFAALITGPVHKGVINDAGIPFTGHTEFFEERSQAKKVVMMLATEELRVALATTHLPLRDIADAITPALLHEVIAILHHDLRTKFGIAEPRILVCGLNPHAGEGGHMGTEEIDTIIPVLDELRAQGMILNGPLPADTLFQPKYLDNADAVLAMYHDQGLPVLKYQGFGRGVNITLGLPFIRTSVDHGTALELAGRGEADVGSFITALNLAIKMIVNTQ
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUT_BRUSU
Sequence: MTAASSSAPTLGIIRLEHAKGLDLPAYETAGSAGMDLRAAVAEDRQIVLLPGRRTLVPTGLILEIPQGYEVQIRPRSGLAFKNGITCLNTPGTIDSDYRGEVKVLLINLGDDDFRIERGMRIAQAVFAPVIQPKIEERAKISETARGAGGFGSTGTA
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: SWS_DROWI
Sequence: MDVLELLRASANGCYNTIFSDAWSQYVSQQITSSLYLYIALGILTVLFVAWFIYFKRLARLRLRDEIARSLNAVTSASGGDLRGLRFRKRDKMLFYGRRMLRKMKNVSGQMYSSGKGYKRRAVMRFARRILQLRRENMPLEMRTVEPPAEYLEETIEGSDRVPPDALYMLQSIRIFGHFEKPVFLKLCKHTQVLELMAGDYLFKITDADDSVYIVQSGMINVYISNADGSTLSLKTVRKGESVTSLLSFIDVLSGNPSYYKTVTAKAMEKSVVIRLPMQAFEEVFRENPDVMIRVIQVIMIRLQRVLFTALRNYLGLNAELVQNHMRNKSITISGHLNSQSQSSQSMRQQTTATATGGTSATALGGQQLPAAVPSLPLQRQPPPPTIAPPLRHSREEHTLSGPNPNPNSGNNVQLPEVHGDAPNIDIYHQQQHGGSTSTGNLSTRRGSLVQPSIGGGGGGSTAQEGGCAAAGAPTIDMRLIQSSAVESLRKELGLPNEDAHIIEPFVEVRELEPNVTLITEGNADDVCIWFVMTGTLAVYQGVADATRSSTATTKSDKSDLLIHFVHPGEIVGGLAMLTGEASAYTIRSRNNSRVAYIRRAAIYQIMRQRPRIVLDLGNGVVRRLSPLVRQCDYALDWIFLESGRAVYRQDESSDSTYIVLSGRMRSVITNPGGKKEIVGEYGKGDLVGIVEMITETSRTTTVMAVRDSELAKLPEGLFNAIKLRYPIVVTKLISFLSHRFLGSMQTRGSTGAPGAPVEANPVTHKYSTVALVPITDEVPLTPFTYELYHSLCAIGPVLRLTSEVVRKQLGQNIFEAANEYRLTSWLAQQEDRNIITLYQCDNSLSPWTHRCMRQADVILIVGLGDRSHLVGKFEREIDRLAMRTQKELVLLYPETTNAKPANTLSWLNARPWVTKHHHVLCVKRIFTRKSQYRINDLYSRVLLSEPNMHSDFSRLARWLTGNSIGLVLGGGGARGAAHIGMLKAIQEAGIPIDMVGGVSIGALMGALWCSERNITTVTQKARQWSKKMTKWFLQLLDLTYPITSMFSGREFNKTIHDTFGDVSIEDLWIPYFTLTTDITASCHRIHTNGSLWRYVRSSMSLSGYMPPLCDPKDGHLLLDGGYVNNLPGHLWRYCRASMSIAGVFPPFCDYRDGHLLLDGCYTNNVPADVMHNLGAAHIIAIDVGSQDDTDLTNYGDDLSGWWLLYKKWNPFTSPVKVPDLPDIQSRLAYVSCVRQLEEVKNSDYCEYIRPPIDKYKTLAFGSFDEIRDVGYVFGKNYFESMAKAGRLGRFNQWFNKEPPKRGNHASLNEYTFIDLAQIVCKLPETYAVNTAEIFSEDEDCDGYISEPSTLNTDRRIQVPRAGNSLSLSEAEMDSDVEIDFRSDSKKDKATQSTPPAPGKDNEDKTDAVDRIPLLTLERPLTDQQQQHSDETDEQETPRAMKDGTNTMTTQTTSPTTDAGSEWAGSESELEKENKNVNTKN
What is the function of this protein?
Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho).  This deacylation occurs at both sn-2 and sn-1 positions of PtdCho.  Its specific chemical modification by certain organophosphorus (OP) compounds leads to distal axonopathy.  Plays a role in the signaling mechanism between neurons and glia that regulates glia wrapping during development of the adult brain.  Essential for membrane lipid homeostasis and cell survival in both neurons and glia of the adult brain (By similarity).
What are the official names of this protein?
Neuropathy target esterase sws, Swiss cheese.
What is the protein family that this protein belongs to?
Belongs to the NTE family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=Sws tethers Pka-C3 to the membrane.