PharMolix/UniProtQA huggingface dataset:
Protein: CCA_SERP5
Sequence: MKTYLVGGAVRDSLLEIPVVDRDWVVVGAAPSELTALGYQQVGKDFPVFLNPKTHEEYALARTERKSGQGYTGFTCYAAPDVTLEEDLQRRDLTINAIARSDDGELIDPFNGVADLQARVLRHVSDAFGEDPLRVLRVARFAARFAHLGFSIAPETAELMRQMARSGELAALTAERVWKETEKALQSQSPQVYFQVLRDCEALGVLFPEIDTLFGVPAPAKWHPEIDTGIHTLMTLAIAAQLSPEVDVRFSALCHDLGKGQTPKELWPHHHGHGPAGVLLVEALCRRLRVPNPVRDLAKLVAEYHDLIHTVNKLRPETLLKLFDAVDVWRKPQRLEQMILTSEADARGRTGFEDNPYPQGDYLRQAFQVANAVSVKEVVASGLQGLAVRDELKRRRQQALAEWKQTQDIPLDQA
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: PSBA_BUMFI
Sequence: MTATLERRESISLWERFCSWITSTENRLYIGWFGVLMIPTLLTATTCYIIAFIAAPPVDIDGIREPVAGSLLYGNNIISGAVIPSSNAIGVHFYPVWEAASVDEWLYNGGPYQLIVLHFLLGVASYMGREWELSYRLGMRPWIFVAFSAPVAAASAVFLVYPIGQGSFSDGMPLGISGTFNFMLVFQAEHNILMHPFHMAGVAGVFGGSLFSAMHGSLVTSSLIRETSEVESTNYGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRALHFFLAAWPVVRIWLTALGVTTMAFNLNGFNFNQSVVDSQGRVINTWADIINRADLGMEVMHERNAHNFPLDLAAGEVLPVAVSAPAVHA
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: DUT_AZOSB
Sequence: MHRIDVKLLDPRLKTHPPAYASAGAAGLDLRACLDAPVLLHPGETTLVPSGLAIHLADPGLAAMVLPRSGLGHKHGIVLGNLVGLIDSDYQGQVFVSVWNRGRDVFTIQPMERIAQLVVVPVLQVGFNVVDDFAASERGEGGFGSTGKH
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: DXR_BURCM
Sequence: MQKRLTLLGSTGSIGDSTLDVVARHPERFSVYALTAHRNGDKLVEQCLRFAPEVAVVGDANTAAHVEAKLRAAGSKTIVLYGPQALVDVSKSDGCDTVVAAIVGAAGLAPSLAAARAGKRILLANKESLVMSGAIFMDAVRDHGAILLPVDSEHNAIFQCMPRDENEHGGISKIILTASGGPFRTREPATLADVTPDEACKHPNWVMGRKISVDSATMMNKGLEVIEAHWIFGLAGDRIDVLIHPQSVIHSLVSYRDGSVLAQLGNPDMRTPIAHALAFPERVDAGVDQLDLAQIVQLSFEKPDYTRFPCLALALKALEEGGIASAALNAANEIAVEAFLERRIGFMAIAATVDAVLNALPNRSPNGLDDVLAADAEARRLAAEIIAKAPAPRVERTV
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: RL31B_PSEF5
Sequence: MKPGIHPDYRTVLFHDTAADVYFLIGSTVDTDRSHTYSDGKTYPYVALDVSSASHPVYTGQQRKTQSEGRIAGFNKRFASFGSGAKAAQ
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: NEP1_PYRIL
Sequence: MIVVLAESALELVPRELWNHPVIQADAKRRGKKPGEILLDRARHHLAMSSLRDASKRGRPDIVHQVLLVFQYSLLNKRGLGRIYIHTQGDYTIYVRWETRIPKNYNNFVSLMEQLYATGRVPPKGEPLIELYKKDLSTLLRELGGRWVVLHESGVKKPFIELGAALLNSVVVIGGFPHGDFTNKWVLEKADAIYKIGDETMDAAQVVYRAITAAEVAAGLL
What is the function of this protein?
Methyltransferase involved in ribosomal biogenesis.  Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M. jannaschii 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase Nep1, 16S rRNA (pseudouridine-N1-)-methyltransferase Nep1.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.
Protein: OPPD_LACLS
Sequence: MESENILEAKQVSVAFRIAGKFQKAIYDIDLSLRRGEVLAIVGESGSGKSTLATAVMGLHNPNQTQITGSILLDEEEVIGKTGDSMASIRGSKVGMIFQNPLTALNPLMKIGQQIKEMLAVHDVYPENQYESRIFQLLEQVGIPNPKRVVNQFPHQLSGGMRQRVMIAIAIANDPDLIIADEPTTALDVTIQAQILDLILEIQKKKNAGVILITHDLGVVAEVADTVAVMYAGQLVEKASVEELFQNPKHPYTRSLLRSNPSAETVSDDLYVIPGSVPSLSEIEYDKDLFLARVPWMKEEAQKVISEKMTEISSNHFVRGQAWKKFEFPDQKLKGGKK
What is the function of this protein?
Part of the binding-protein-dependent transport system for oligopeptides.  Probably responsible for energy coupling to the transport system.
What are the official names of this protein?
Oligopeptide transport ATP-binding protein OppD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL15_ZYMMO
Sequence: MSFKLNSLKDNAGSRVGRVRVGRGIGSGLGKTAGRGQKGQKSRSGVSINGFAGGQMPIYMRLPKRGFNNVFSKDYAEVNLGVVQKLIESGRLDAKNPIDHQALKAAGVARGGKDGVRILGKGEIASKVAFKVAGISKAAREAVEKAGGSVEIIARRNVEKTDA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: PDX1_MOUSE
Sequence: MNSEEQYYAATQLYKDPCAFQRGPVPEFSANPPACLYMGRQPPPPPPPQFTSSLGSLEQGSPPDISPYEVPPLASDDPAGAHLHHHLPAQLGLAHPPPGPFPNGTEPGGLEEPNRVQLPFPWMKSTKAHAWKGQWAGGAYTAEPEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLTERHIKIWFQNRRMKWKKEEDKKRSSGTPSGGGGGEEPEQDCAVTSGEELLAVPPLPPPGGAVPPGVPAAVREGLLPSGLSVSPQPSSIAPLRPQEPR
What is the function of this protein?
Activates insulin and somatostatin gene transcription.  Key regulator of islet peptide hormone expression but also responsible for the development of the pancreas, most probably by determining maturation and differentiation of common pancreatic precursor cells in the developing gut.  As part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element.  Binds the DNA sequence 5'-CC[CT]TAATGGG-3'.
What are the official names of this protein?
Pancreas/duodenum homeobox protein 1, Insulin promoter factor 1, IPF-1, Islet/duodenum homeobox 1, IDX-1, Somatostatin-transactivating factor 1, STF-1.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family. IPF1/XlHbox-8 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol.
Protein: MNMC_PSEU2
Sequence: MTITRHAQIDWDEHGNPRSRDFSDVYFSTESGLEETRHVFLVQNDLRRRFTELQDGGRLIIGETGFGTGLNFLCAWQLFDECAPANARLQFVSVEKYPLSHADLQRALALWPELSPFAGQLLDQYVAVHEGFQRLVFAGGRVTLTLLIGDALQMLPQLDGQMDAWFLDGFAPAKNPEMWTPELFAELARLSTSSTTIGTFTSTGWVRRSLNAAGFKMKRVPGIGHKWEVLRGTFIAWPEDVAHPPAAKPWLARPAPIGGERKALVIGAGLAGCATAQSLAQRGWQVSLLERHAAPAQEASGNPQGVLYLKLSAHGTALSQLILSGFGHTRRLLERLQRGVDWDACGVLQLTFDDKEALRQKQLADAFPESLLHLLDKPAAEAQSGVALNSGGLFYPEGGWVHPPALCHAQAAHANIRLIAHQQALELRRVDDQWQVWSEEQLVDSAPVVVLAGAADIQQFSQSADLPLKRIRGQITRLPQTQASTALRSVVCAEGYVAPARLGEHTLGASFDFNSTDLTPNLADHLDNLGLLREISEDLTSRLDTADLSPEQLQGRAAFRCTSPDYLPIVGPLADREAFMQAYAALGKDARQVPDITCPWLDGLYVNSGHGSRGLITAPLCGELIAAWLDNEPLPLPRSVAEACHPNRFALRGLIRGKGKQTVGH
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA1_MYCBO
Sequence: MLSKLLRLGEGRMVKRLKKVADYVGTLSDDVEKLTDAELRAKTDEFKRRLADQKNPETLDDLLPEAFAVAREAAWRVLDQRPFDVQVMGAAALHLGNVAEMKTGEGKTLTCVLPAYLNALAGNGVHIVTVNDYLAKRDSEWMGRVHRFLGLQVGVILATMTPDERRVAYNADITYGTNNEFGFDYLRDNMAHSLDDLVQRGHHYAIVDEVDSILIDEARTPLIISGPADGASNWYTEFARLAPLMEKDVHYEVDLRKRTVGVHEKGVEFVEDQLGIDNLYEAANSPLVSYLNNALKAKELFSRDKDYIVRDGEVLIVDEFTGRVLIGRRYNEGMHQAIEAKEHVEIKAENQTLATITLQNYFRLYDKLAGMTGTAQTEAAELHEIYKLGVVSIPTNMPMIREDQSDLIYKTEEAKYIAVVDDVAERYAKGQPVLIGTTSVERSEYLSRQFTKRRIPHNVLNAKYHEQEATIIAVAGRRGGVTVATNMAGRGTDIVLGGNVDFLTDQRLRERGLDPVETPEEYEAAWHSELPIVKEEASKEAKEVIEAGGLYVLGTERHESRRIDNQLRGRSGRQGDPGESRFYLSLGDELMRRFNGAALETLLTRLNLPDDVPIEAKMVTRAIKSAQTQVEQQNFEVRKNVLKYDEVMNQQRKVIYAERRRILEGENLKDQALDMVRDVITAYVDGATGEGYAEDWDLDALWTALKTLYPVGITADSLTRKDHEFERDDLTREELLEALLKDAERAYAAREAELEEIAGEGAMRQLERNVLLNVIDRKWREHLYEMDYLKEGIGLRAMAQRDPLVEYQREGYDMFMAMLDGMKEESVGFLFNVTVEAVPAPPVAPAAEPAELAEFAAAAAAAAQQRSAVDGGARERAPSALRAKGVASESPALTYSGPAEDGSAQVQRNGGGAHKTPAGVPAGASRRERREAARRQGRGAKPPKSVKKR
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 1.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: Y031_RICTY
Sequence: MKTLKALKIFIIVYISSVSLESFAGFGESCSNLPITSDGYLETYTAYGYIIRSIDMKDPRGNCNPYTSSITFCFKNVEGSTSPCTIYTLNEGDARKISDLSTDNNPNLGANTVLKNIVLTVKKFGNDLCLAMPTSRGPMPVACKSLNATPAPTNPKYENCNIGKSCYTGANYSQSLINFSGLAVQCLSETLNKIFFTGNSCSSQDQNSRITHLAAFSTFQGYLKRIIGAALILYTMFFAFNMALNKEYATTEKITLFIIKFLFVVYFSIGLEPLNFSGGQTVKENGMLKYGLPLLTGAAPDFAEMIFNAAGSRGLCQFDNSKYKDGYKFYGLWDAIDCRIGYYLGLDLLYNIDKNGILGHSVGNGPGGNNKPIPNFDPDSKKDRPHDLSKAGALRFFTVMFGFLMSGHIIILVAGIAFSVIFLSILLYFITHYLVCMITIYVMTYISPIFIPMVLFTRTKAYFDGWVKVCISCALQPAVVAGFIALLITMYDSAIFKNCEFLRYDYEKGDIRFSTFELRLPSIDADKCQESFGYKMLKYYAGEGWEEHLLILFPIKSIVRDVVSILAELLCVLVFSVIFYYFSKSIGRFAADLTNGPNMDAVTASPTKIVDLVKKGAAFLQDASSVHAQGKSPVEDKPDIGSKRKDGVQQGEDSENSSGGELADLASGSGGGKL
What are the official names of this protein?
Uncharacterized protein RT0031.
What is the protein family that this protein belongs to?
Belongs to the TrbL/VirB6 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TATB_MYCBP
Sequence: MFANIGWGEMLVLVMVGLVVLGPERLPGAIRWAASALRQARDYLSGVTSQLREDIGPEFDDLRGHLGELQKLRGMTPRAALTKHLLDGDDSLFTGDFDRPTPKKPDAAGSAGPDATEQIGAGPIPFDSDAT
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: THIO_STAEQ
Sequence: MAIVKVTDSDFDSKIESGVKLVDFWATWCGPCKMIAPVLEELAGDYDGKADILKLDVDENPSTAAKYEVMSIPTLIVFKDGEPVDKVVGFQPKENLAEVLDKHL
What is the function of this protein?
Component of the thioredoxin-thioredoxin reductase system.  Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (By similarity).
What are the official names of this protein?
Thioredoxin, Trx.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
Protein: THAP3_HUMAN
Sequence: MPKSCAARQCCNRYSSRRKQLTFHRFPFSRPELLKEWVLNIGRGNFKPKQHTVICSEHFRPECFSAFGNRKNLKHNAVPTVFAFQDPTQQVRENTDPASERGNASSSQKEKVLPEAGAGEDSPGRNMDTALEELQLPPNAEGHVKQVSPRRPQATEAVGRPTGPAGLRRTPNKQPSDHSYALLDLDSLKKKLFLTLKENEKLRKRLQAQRLVMRRMSSRLRACKGHQGLQARLGPEQQS
What is the function of this protein?
Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1.
What are the official names of this protein?
THAP domain-containing protein 3.
Protein: OXLA_LACMT
Sequence: MNVFFMFSLLFLAALGSCADDRNPLGECFRETDYEEFLEIAKNGLRATSNPKHVVIVGAGMSGLSAAYVLAEAGHQVTVLEASERAGGRVRTYRNDKEGWYANLGPMRLPEKHRIVREYIRKFGLQLNEFHQENDNAWHFIKNIRKRVGEVKEDPGLLQYPVKPSEEGKSAGQLYEESLGKVAEELKRTNCSYILNKYDTYSTKEYLLKEGNLSPGAVDMIGDLLNEDSGYYVSFIESLKHDDIFGYEKRFDEIVDGMDKLPTSMYQAIKEKVRFNARVIKIQQNDREVTVTYQTSANEMSPVTADYVIVCTTSRATRRITFEPPLPPKKAHALRSVHYRSGTKIFLTCTKKFWEDDGIRGGKSTTDLPSRFIYYPNHNFTSGVGVIIAYGIGDDANFFQALDFKDCGDIVINDLSLIHQLPKKDIQTFCYPSMIQRWSLDKYAMGGITTFTPYQFQHFSEALTAPFKRIYFAGEYTAQFHGWIDSTIKSGLTAARDVNRASENPSGIHLSNDNEL
What is the function of this protein?
Catalyzes an oxidative deamination of predominantly hydrophobic and aromatic L-amino acids, thus producing hydrogen peroxide that may contribute to the diverse toxic effects of this enzyme (PubMed:22963728).  Is highly active on L-Met=L-Leu>>L-Phe>L-Trp>L-Tyr>L-Ile, and weakly or not active on L-His, L-Arg, L-Val, L-Gln, L-Thr, L-Lys, and L-Ser (PubMed:22963728).  Exhibits a low myotoxicity (a mild myonecrosis is observed after injection in mice quadriceps muscle) (PubMed:22963728).  In vitro, is cytotoxic to a lot of human cell lines, including AGS (IC(50)=22. 7 ug/ml), MCF-7 (IC(50)=1. 4 ug/ml), HL-60, HeLa and Jurkat cells, as well as to the parasite Leishmania brasiliensis (IC(50)=2. 22 ug/ml) (PubMed:22963728).  This cytotoxicity is dependent on the production of hydrogen peroxyde, since it is inhibited by catalase, a hydrogen peroxyde scavenger (PubMed:22963728).
What are the official names of this protein?
L-amino acid oxidase Lm29, LmLAAO, LAO.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family. FIG1 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SAMC_HUMAN
Sequence: MDRPGFVAALVAGGVAGVSVDLILFPLDTIKTRLQSPQGFSKAGGFHGIYAGVPSAAIGSFPNAAAFFITYEYVKWFLHADSSSYLTPMKHMLAASAGEVVACLIRVPSEVVKQRAQVSASTRTFQIFSNILYEEGIQGLYRGYKSTVLREIPFSLVQFPLWESLKALWSWRQDHVVDSWQSAVCGAFAGGFAAAVTTPLDVAKTRITLAKAGSSTADGNVLSVLHGVWRSQGLAGLFAGVFPRMAAISLGGFIFLGAYDRTHSLLLEVGRKSP
What is the function of this protein?
Mitochondrial S-adenosyl-L-methionine/S-adenosyl-L-homocysteine antiporter.  Mediates the exchange of cytosolic S-adenosyl-L-methionine, the predominant methyl-group donor for macromolecule methylation processes, for mitochondrial S-adenosylhomocysteine(SAH), a by-product of methylation reactions.
What are the official names of this protein?
Mitochondrial S-adenosylmethionine carrier protein, SAM carrier, Solute carrier family 25 member 26.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
Protein: MURI_RHIME
Sequence: MTKTELKPILVFDSGIGGLTVLREARVLMPERHFIYVADDAGFPYGGWEEGALKERVIALFGRLLAELDPEICIIACNTAFTLVGADLRAAYPQMTFVGTVPAIKPAAERTRSGLVSVLATPGTVKRAYTRDLIQSFASQCHVRLVGSENLARMAEAYIRGDALADEAVLAEIEPCFVEAEGKRTDIVVLACTHYPFMSNVFRRLAPWPVDWLDPAEAIARRARSLVPLPNGFEPLNGEDPAIFTSGRPDFATRRLMQGFGLRVMADAVSADRRERI
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: SCPB_HALH5
Sequence: MTLKELQAAIEGILFVRGDEGVTLEELCDLLELSTDVVYAALEELRLSYTDEARGLRIEEVAHAFRLSTKPELAPYFKKLALSTLQSGLSQAALETLAIIAYRQPITRIEVDEVRGVKSEKAIQTLTSRLLIKEVGRAQGTGRPILYGTTPQFLDHFGLKSLKELPPLPEDIDESSIGEEADLFFQQMEQGSLFHEE
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein B.
What is the protein family that this protein belongs to?
Belongs to the ScpB family.
Protein: SYM_JANMA
Sequence: MSKPLPRKLFVTTALPYANGAFHVGHIMEYIQADIWVRFQRMQGNEVHFVGADDAHGAPIMIAAEKAGLTPQQFVANIAAGRKQYLDGFHIEFDNWSSTDSPENHELSREIYRRLRDDAKLITTKSVEQFYDPVKEMFLPDRYIKGECPKCGTKDQYGDSCENCSAVYAPTDLKHPYSTLTGATPVRKSSDHFFFRLSDPKCVAFLREWALDGQRLQSEVANKAKEWLEGEGGLGDWDISRDAPYFGIEIPDAPGKYFYVWLDAPVGYLATLKNYFDKTGRDFDAFMADPSTEQYHFIGKDITYFHTLFWPAMLKFADMKVPNNVFVHGFITVSGEKMSKSRGTGISPLRYLEIGMNPEWLRYYIAAKLSSKVEDIDFTSDDFIARVNSDLIGKYINIASRAAGFITKKFDGRVATDWATSDDAFLSRLRNVASEIQALYDQREYGKALRAIMEQADAINAYVDANKPWELAKDPAKEAALQEVCSRLLEAFRILTIYLKPVLPALAKQVEAQLNIAPLEWHHIITPLPHGHQINPYVHLMTRVEPKMLDALFDMPALVDATVGVPTSPSNKDGDTNGNGHAIESIAPEIKIDDFAKIDLRIAKIVNCEHVEGSDKLLRLTLDVGEGRMRNVFSGIKSAYKPEDLIGKLTVMVANLAPRKMKFGISEGMVLAASAADEKANPGIYILNPWPGAEPGMRVG
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_FLAJ1
Sequence: MAYLFTSESVSEGHPDKVADQISDALIDNFLAFDADSKVACETLVTTGQVILAGEVKSNTYLDVQQIAREVIRKIGYTKSEYMFEANSCGILSAIHEQSADINQGVDRAKPEEQGAGDQGMMFGYATNETENFMPLALDLSHKLLQELAILRRENKEITYLRPDAKSQVTLEYSDDNKPTRIDAIVISTQHDDFDEEAAMLAKIKKDVIEILIPRIIAKNPEHAHLFNDKINYHINPTGKFVIGGPHGDTGLTGRKIIVDTYGGKGAHGGGAFSGKDPSKVDRSAAYATRHIAKNLVAAGVADEILVQVSYAIGVAEPMGIFIETYGTSKVNLTNGEIAKKVEAIFDMRPYFIEQRLKLRNPIYSETAAYGHMGRKPETVTKTFSAPGGNEKTVTVELFTWEKLDFVDQVKTAFGL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_BURCM
Sequence: MSRVGKSPIALQGAEVKLADGAITVKGPLGTITQAINPLVNVANNDGTLNLSPVDESREANALSGTMRAIIANAVQGVTKGFERKLTLVGVGYRAQAQGDKLNLSLGFSHPVVHQMPEGVKAETPTQTEIVIKGINKQQVGQVAAEVRGYRPPEPYKGKGVRYSDEVVILKETKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: YHBP_SHIFL
Sequence: METLIAISRWLAKQHVVTWCVQQEGELWCANAFYLFDAQKVAFYILTEEKTRHAQMSGPQAAVAGTVNGQPKTVALIRGVQFKGEIRRLEGEESDLARKAYNRRFPVARMLSAPVWEIRLDEIKFTDNTLGFGKKMIWLRDSGTEQA
What are the official names of this protein?
UPF0306 protein YhbP.
What is the protein family that this protein belongs to?
Belongs to the UPF0306 family.
Protein: PROB_MICAN
Sequence: MNQTIVIKIGTSSLTDNETGQLSLSTIAALVEVLTRLRAAGHRVVLVSSGAVGVGCRRLGIQERPKKIALKQAIAAVGQGRLMRIYDDLFTSLGQPIAQILLTRPELMERTCYVNAYNTFQALFELGVIAIVNENDTVAIDELKFGDNDTLSALVASLIEADWLFILTDVDRLYSADPRLFPEAAAIARVSPAELAQLSIDAGSSGSQWGTGGMATKLAAARIATSAGVEMAITRGRQPGNILKIMAGEAIGTRFEAQKRSDNARKRWIAYGLLPMGKIYLDAGAIQAICQGGKSLLAAGITKVEGEFSASESVQLCDQEGRELARGIVNYSSEEIDRVKGQHSERIASLLGYMAAETIIHRDNLVILSASSTTSTNKG
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXR_PARXL
Sequence: MQKRLTLLGSTGSIGDSTLDVVARHPERFSVYALSAHRNGDKLVEQCLRFEPEVAVVGDADTAARVAAKLREAGCKTEVTYGPQALVDVSESDGCDTVVAAIVGAAGLAPSLAAARAGKRILLANKEALVMSGAIFMDAVRDNGAVLLPVDSEHNAIFQCLPREAALHGGVSKIILTASGGPFRTREPATLVDVTPEEACKHPNWVMGRKISVDSATMMNKGLEVIEAHWLFDLPGERIDVLIHPQSVIHSLVSYADGSVLAQLGNPDMRTPIAHALAFPDRVDSGVAQLDLAQIASLSFEKPDYARFPCLALAMKALAEGGVASAALNAANEIAVEAFLSRQIGFMAIAQVVDAVLNTLPNRSAHALEDVLEADAAARRAAAEFIARLPDGARRTERAVQ
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: MQO_BACCN
Sequence: MSNMQKKTDVILIGAGIMSATLGSLLKELAPEWEIKMFEKLEGAGEESSNEWNNAGTGHSALCELNYTSEKPDGSIDIKKALKINEQFQLSRQFWSYLVNSNLIRNPQKFIMPIPHMSLVQGEKNVTFLKKRFKALSNIPLFQGMEFSDDPEKLKEWMPLIMEGRTSNEPIAATKMESGTDVNFGALTRMLFEHLQNKNVELNYKHSVENIKRMKNGLWEVKVHDMNNGKIEYHTAKFVFIGAGGGSLPLLQKTGIPESKHIGGFPVSGLFMVCNNPKVIEKHHAKVYGKAKVGAPPMSVPHLDTRYIDNKKTLLFGPFAGFSPKFLKTGSNLDLLGSVKPNNVLTMLAAGVKEMALTKYLIQQVMLSNEKRIEELREFIPNAKGEDWDVVVAGQRVQVIKDTETGGKGTLQFGTEVVSAADGSIAALLGASPGASTAVNVMLEVLEKCFPQYMEKWEEKIKHMIPSYGISLVENPKLFQEIHTSTSKTLGLSKKEAVYS
What are the official names of this protein?
Probable malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: SYL_LACDB
Sequence: MYNHKVVEKKWQKYWLENKTFKTGTDPEKPKYYVLDMFPYPSGKGLHVGHPEGYTATDIMARMKRAQGYNVLHPMGWDAFGLPAEQYALQTGNDPATFTDENIAHFKKQLQALGFSYDWDREIKTTDPNYYKWTQWIFEQMYKMGLAYEAEVPVNWSPDLGTVVANEEVIDGKTERGGYPVYRRKMRQWMLKITAYADRLLDDLDDLDWPEPIKEMQRNWIGRSVGAQVTFKIKDSDKSFAVFTTRPDTLFGCSYTVLAPENELVKEITSPEQKEAVDAYIKSIESKSDLERTDLNKDKTGVFTGAYAINPVNGEEVPVWISDYVLATYGTGAVIAVPAHDERDYAFATKFDLPIKEVVEGGDISKEAFAGDGVHVNSDFLNGLHNEEAKAKMVDWLTEKGVGEKKVNYKMRDWNFSRQRYWGEPIPVIHWEDGETTLVPEDELPLRLPKESNIKPSGTPESPLANLTDWVNVVDENGRKGKRETNTMPQWAGSSWYFLRYIDPHNDKALADPELLKKWMPVDLYIGGAEHATLHLLYARFWHKVLYDLGVVPTKEPFQKLYNQGLILKNHEKMSKSRGNVVNPDDVVDEYGADSLRTYEMFMGPLNASIDWDDNGPSGVKKFLDRVWRTFVNDLDLDPIPSEKITDKNDGKLDKIYNETVKTVTEHFEELRFNTAISQMMVFMNACQKVDKIPREYAEGFVKLMAPVAPHMMEEIWHVFGHDESVQFAAWPTYDASKLVESTVEMAVTVNGKKRGNFQIAKDASREEAQAAATALPHVKEFLEGKEIKKVIVVPNKIVNIVAK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.