PharMolix/UniProtQA huggingface dataset:
Protein: RBL_SHEAR
Sequence: MSPQTETKAGVGFKAGVKEYKLTYYTPEYETKDTDILAAFRVTPQPGVPPEERGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVPGEEEQFIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPVAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKSQAETGEIKGHYLNATAGTCEDMMKRAVFARELEVPIVMHDYLTGGFTANTTLSHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHSGTVVGKLEGERDITLGFVDLLRDDYIEKDRSRGIYFTQDWVSLPGVLPVASRGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVKARNEGRDLAREGGEIIREACKWSP
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GA1_GIBF5
Sequence: MPHKDNLLESPVGKSVTATIAYHSGPALPTSPIAGVTTLQDCTQQAVAVTDIRPSVSSFTLDGNGFQVVKHTSAVGSPPYDHSSWTDPVVRKEVYDPEIIELAKSLTGAKKVMILLASSRNVPFKEPELAPPYPMPGKSSSGSKEREAIPANELPTTRAKGFQKGEEEGPVRKPHKDWGPSGAWNTLRNWSQELIDEAGDIIKAGDEAAKLPGGRAKNYQGRRWALYTTWRPLKTVKRDPMAYVDYWTADEEDGVSFWRNPPGVHGTFESDVLLTKANPKHKWYWISDQTPDEVLLMKIMDTESEKDGSEIAGGVHHCSFHLPGTEKEEVRESIETKFIAFW
What is the function of this protein?
GA4 desaturase; part of the gene cluster that mediates the biosynthesis of gibberellins (GAs), diterpenoids that may provide a selective advantage during infection of the preferred host plant, rice (PubMed:23825955, PubMed:9917370, PubMed:10347043, PubMed:12750377, PubMed:15925394).  Gibberellins (GAs) are diterpenoids and are synthesized via the mevalonate pathway (PubMed:12750377).  Biosynthesis of the major metabolite GA3 (gibberellic acid) from geranylgeranyl diphosphate (GGPP) requires 13 steps (PubMed:12750377).  The GGPP produced by the geranylgeranyl diphosphate synthase GGS2 is converted to ent-kaurene via ent-copalyldiphosphate in a two-step cyclization reaction performed by the bifunctional ent-copalyl diphosphate synthase/ent-kaurene synthase enzyme (CPS/KS) (PubMed:9745028, PubMed:10803977, PubMed:12750377).  Ent-Kaurene is metabolized to GAs by a series of oxidation reactions catalyzed by cytochrome P450 monooxygenases (PubMed:9917370, PubMed:12750377).  Cytochrome P450 monooxygenase P450-4 is an ent-kaurene oxidase that catalyzes the three oxidation steps between ent-kaurene and ent-kaurenoic acid (PubMed:11472927).  The highly multifunctional cytochrome P450 monooxygenase P450-1 then catalyzes four steps involving oxidation at two carbon atoms, in the main pathway from ent-kaurenoic acid to GA14 via GA12-aldehyde as well as producing kaurenolides and fujenoic acids as by-products (PubMed:11320210).  The cytochrome P450 monooxygenase P450-2 then converts GA14 to GA4 by removal of C-20 (PubMed:11943776).  GA4 is further converted to GA7 by the GA4 desaturase DES via 1,2-desaturation before cytochrome P450 monooxygenase P450-3, a 13-hydroxylase, hydroxylates GA7 to GA3, the final product of the GA-biosynthetic pathway (PubMed:12750377).
What are the official names of this protein?
Gibberellin cluster GA4 desaturase, DES.
What is the protein family that this protein belongs to?
Belongs to the asaB hydroxylase/desaturase family.
Protein: RS8_ARCFU
Sequence: MSVDTLSNAMIAIKNAEMVGEKKCEIKPASKLIGNVLKVMKDYGYIKGFEYVENHRGGKFIVELSGNINDCGAIRPRFSSSVTEYEMYEKRYLPARDFGILIVSTTKGVMSQKDARKQRLGGVLLAYVY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: TORSO_DROME
Sequence: MLIFYAKYAFIFWFFVGSNQGEMLLMDKISHDKTLLNVTACTQNCLEKGQMDFRSCLKDCRINGTFPGALRKVQENYQMNMICRTESEIVFQIDWVQHSRGTEPAPNATYIIRVDAVKDDNKETALYLSDDNFLILPGLESNSTHNITALAMHGDGSYSLIAKDQTFATLIRGYQPSKMGAVNLLRFVPQPDDLHHIAAEIEWKPSAESNCYFDMVSYSTNSVNMDEPLEVQFRDRKKLYRHTVDNLEFDKQYHVGVRTVNIMNRLESDLQWLPIAVPSCLDWYPYNYTLCPPHKPENLTVTQKQYLPNILALNITWARPRYLPDNYTLHIFDLFKGGTELNYTLDQNRSHFYVPKITVLGSHFEVHLVAQSAGGKNVSGLTLDKVHRGVLLSEGNMVKLVLFIIVPICCILMLCSLTFCRRNRSEVQALQMDAKDAKASEFHLSLMDSSGLLVTLSANESLEVMDELEVEPHSVLLQDVLGEGAFGLVRRGVYKKRQVAVKLLKDEPNDEDVYAFKCEIQMLKAVGKHPNIVGIVGYSTRFSNQMMLLIEYCSLGSLQNFLREEWKFRQEQNAIGLKKNLEQNVDNRRFNRLPRNSIHDRIEDINNSMLSTVEEESESDQTHSSRCETYTLTRITNAADNKGYGLEDIENIGGSYIPKTAEAPKDRPKRKLKPQPKKDSKQDFKSDNKKRIFENKEYFDCLDSSDTKPRIPLKYADLLDIAQQVAVGMEFLAQNKVVHRDLAARNVLISVDRSIKIADFGLSRDVYHENVYRKSGGSGKLPIKWLALESLTHQVYTSQSDVWSFGVLLYEITTLGGMPYPSVSPSDLLQLLRQGHRMKRPEGCTQEMFSLMESCWSSVPSHRPTFSALKHRLGGMILATNDVPERLKQLQAATESKLKSCDGLNSKVEQVPCEEELYLEPLN
What is the function of this protein?
Probable receptor tyrosine kinase which is required for determination of anterior and posterior terminal structures in the embryo (PubMed:2927509, PubMed:8423783).  During postembryonic development, involved in the initiation of metamorphosis probably by inducing the production of ecdysone in response to prothoracicotropic hormone Ptth (PubMed:19965758).  Binding to Ptth stimulates activation of canonical MAPK signaling leading to ERK phosphorylation (By similarity).
What are the official names of this protein?
Tyrosine-protein kinase receptor torso.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: LUTC_GEOTN
Sequence: MTRGTIQNRDAFLQNIAKRLGRSPRLSGVSQPQWDYAPQWTVFAGYSQDDLLSALREQCKLIHTDYIETTSSELAGALKQQVAAYGGGPVIVPDDPRFAEYGLSALLHDEWPAEQTAVHVWNSSLGRQNIDAAEQANVGIAFSEITLAESGTVVLFSRNEQGRTIHFLPKTYIAIVPKSSVVPRMTQAAAYIHEQIEKGAVVPSCINFITGPSNSADIEMNLVVGVHGPMKAAYIVVTDR
What is the function of this protein?
Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source.
What are the official names of this protein?
Lactate utilization protein C.
What is the protein family that this protein belongs to?
Belongs to the LutC/YkgG family.
Protein: RSMF_SALPA
Sequence: MAQHAVYFPDAFLTQMREAMPSTLSFDEFISACQRPLRRSIRINTLKISVADFLALIAPYGWSLTPIPWCHEGFWIERDDEEALPLGSTAEHLSGLFYIQEASSMLPVAALFADDNHPQRVMDMAAAPGSKTTQIAARMGNRGAILANEFSASRVKVLHANISRCGIANTALTHFDGRVFGAALPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESNLDIAATQRELLDSAFHALRPGGTLVYSTCTLNRQENEDVCLWLKETYADAVEFLPLGDLFPDADRALTPEGFLHVFPQIYDCEGFFVARLRKMSSLPAMPAPGYKVGAFPFTPLKGREALNVTQAANAVGLLWDENLHLWQREKEVWLFPAEIESLIGKVRFSRLGIKLAESHNKGYRWQHEATIALACPTHAHAFELSAQEAEEWYRGRDIYPQTPPAADDVLVTFQHQPLGLAKRIGARIKNSYPRELVRDGKLFTGNS
What is the function of this protein?
Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase F, 16S rRNA m5C1407 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmF.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIA_NITEC
Sequence: MTFSERFSAYARLTRLDKPIGILLLLWPTLWGLWLAADGMPDPMILVIFVLGTILMRSAGCAINDFADRKIDPHVSRTRNRPLATGIISSREALLVAAGLSLCAFLLILPLNLLTILLSVPALLLAISYPFTKRFFAMPQAYLGIAFSFGIPMAFAAQTGTVPPLAWLLVLANLFWVIAYDTEYALVDLADDLKIGIKTSAITFGRFDVAGILLCHITFLSILTYAGILLQRGIWFYGALLVALGLVIVQYTMIRNREPARCFQAFLHNNRVGAVIFAGILLDTLI
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DTD_ACTPJ
Sequence: MIGLIQRVKWAKVEVEGQTVGEITQGLLVLLGVEQGDDQAKADKLLEKVLNYRVFSDEQGKMNLNVQQAGGSLLVVSQFTLAADTNKGLRPSFSRGAAPQEANALYEYFHQQAARKIHTQTGQFAADMQVSLQNDGPVTFWLQI
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHEB_THEKO
Sequence: MPLSKKIRVMVVDDSAFMRRILRDILESDPDIEVCCEARDGIEAIEKVKTEKPDVITLDIEMPRMNGLDALKFIMSKYPTPVIMVSALTQEGAEATIKALEYGAIDFIPKPSSSISINMRELRDEIIAKVKEAAKVPRRFLQLRRRRVLSEQLKKAKKVGEPARRAVAIAASTGGPQSLLKVFEKLPGELDAAILLVQHMPPGFTRSFAARLDRISKLNVKEAEDGEVVNKDWAYVAPGDYHMEVTLRNGKPTIKLYKGPKIHGVRPAADPMMKSVAEVFGRRTVGVVMTGMGRDGAEGIVAIKRKGGITIAQDKETSIIYGMPKAAAETGMVDYIVPLDKIADTIVMALRKIPR
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_MAGSA
Sequence: MSEAIAIAAELRDGSGKGAARATRRAGKVPGVIYGDKKAAICIQMDPRVVWAQISKTGFFTQLFNVDLGKDGKHLCLARDVQMHPVTDQPIHVDFMRVSADHAIHVKVPVHFTNELKSPGIKKGGVLNVELHEIEITCSPNDIPHEILIDLDGLEIGASIHLSDLKLPAGAKPYHVASGATVASIAAPTVARAETTETEAAG
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: PRP5_ASPFU
Sequence: MARHGDTRSPSPVGSTYSSSRRSRRDDDRYEKSRRDDLRSYRRSRSPERRYRDRDRDSYRRRDRSVDRRDDHRDEDSYRSSRRDRSRDRRRSRDRGDDRDHRRKSRERDYRSRRDDSRDRARRRTDDSADLKHKSRRDDSRTRNLDSKPREASKPSTPAPTAPTEDEKRAERLAKLEAWKQKQAAERERKQREAAAAGGARSILEEIDRKSGLSPAVGSPQSPATPTTDATPTPYSGKFDPKAIVRNAAPAPSTPAVLGNDVAVPQSAKASASSSSMNNHVQANKHPAANSTTSCKLYIPTIRFLQIANVTCTATSTVKRNVGGFGLGAKQVADAEKSSAVKTLGFGEEESKRKKLERLPTPPLEDAKDDMGAVDAAVEDEDDVDMQDGGTEEENAAAARAAAERREERLQSEALRAQSKEAALQSNGDVEMNDVPHQAESEKMEVDAAEEEVDPLDAFMSELAETAPPKKTTGARFTKAKDQQPEAMFGDEHDVDLTAVGEGDADDFLAIANKAKKKKDIPTVDHEKMEYEPFRKKFYTEPSNLAEMTDEEAASLRLELDGIKVRGVDVPKPVMKWSQCGLGVQTLDVIQKLGYENPTSIQSQAIPAIMSGRDVIGVAKTGSGKTIAFLIPMFRHIRDQRPLENMEGPIGLIMTPTRELATQIHKDCKPFLKALNLRAVCAYGGAPIKDQIAELKRGAEIVVCTPGRMIDLLAANAGRVTNLRRVTYVVLDEADRMFDMGFEPQVMKIMANIRPDRQTVLFSATFPRNMEALARKSLTKPIEIVVGGKSVVAPEITQIVEVRNEDTKFVRLLEILGNLYSDDANEDARALIFVDRQEAADTLLRELMRKGYPCMSIHGGKDQIDRDSTIEDFKAGIFPVLIATSVAARGLDVKQLKLVVNYDAPNHLEDYVHRAGRTGRAGNTGTAVTFLTEEQERYSVDIAKALRQSGQKVPEPVQKMVDSFLEKVKAGKEKASASGFGGKGLERLDQERDAARMRERRTYKTGEEGEDEEDKEDKAEKADERFSKIVSSVQSAAAAATTPLPGVPKGIDLDGKITVHRTEKDPAGASKNPLDKVGSAVADIHARLSRAGVMRSGVPIDNRGPDAGAFHATLEINDFPQKARWAVTNRTNVAKILEATGTSITTKGSFYPAGKEPGPGENPKLYILVEGETELAVTNAMRELMRLLKEGTLAAADSDARAPVGGRYNVV
What is the function of this protein?
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing.  Catalyzes an ATP-dependent conformational change of U2 snRNP.  Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
What are the official names of this protein?
Pre-mRNA-processing ATP-dependent RNA helicase prp5.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: HSLV_YERPY
Sequence: MTTIVSVRRDGHVVIGGDGQVTLGNTVMKGNAKKVRRLYNNKVIAGFAGGTADAFTLFELFERKLEMHQGHLTKAAVELAKDWRTDRMLRKLEALLAVADETASLIITGNGDVVQPEDDLIAIGSGGPYAQSAARALLENTELGARDIVEKSLSIAGDICIYTNRFQTIEELTY
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSB_FRATH
Sequence: MANIHIVIPARLKSTRLPNKMLADIAGKPMIQRVYEQVTKSKFDSIIIATDSQKIKDIAESFGAKVVLTRDDHQSGTDRIAEAVTKLGFAYEDIVVNVQGDEPLIPIENIEQAAQLLIDKSEAVVSTLCEKITDVEDIYNPNNVKVVFDKNNYALYFSRASIPFERGFSEKEQINISEFFRHIGIYAYRVAFLKHYAELTVSPIEKYEALEQLRVLYNGYKIAIEQSAKSTPAGVDTLQDLEKVRKLFNV
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAK_MAGSA
Sequence: MSKVIGIDLGTTNSCVAVMEGKNAKVIENAEGMRTTPSMTAFTESGERLVGQPAKRQAVTNPTSTLFAIKRLIGRRFEDPITKKDMNLVPYHIVAGDNGDAWVEARDAKYSPSQVSAFILQKMKETAEGYLGEKVTQAVITVPAYFNDAQRQATKDAGRIAGLEVLRIINEPTAAALAYGLEKKGAGTIAVYDLGGGTFDVSVLEIGDGVFEVKSTNGDTFLGGEDFDARIMDYLADEFKKEQGIDLRKDRLALQRLKEAAEKAKIELSSSMQTEVNLPFITADASGPKHLNIKLTRSKLEALVEDLVARTVEPCKAALKDAGVKASEIDEVILVGGMTRMPKIQEVVKEFFGREPHKGVNPDEVVAIGAAIQGGVLKGEVKDVLLLDVTPLSLGIETLGGVFTRLIDRNTTIPTRKSQVFSTAEDNQTAVTIRVFQGEREMAADNKVLGQFDLVGIPPAPRGVPQVEVTFDIDANGLVNVSAKDKATGKEQQIRIQASGGLSDADIEKMVKEAEAHAAEDKKRKELIEARNHADGLIHTTEKSLKEFGDKAGAELTGAIEKEITALKAVMDGDDVEAIKAKTESLMQASMKLGEAMYKAQEAAGGAEAEAAAGGHGGASGSHDDKVVDADFEEVDGDKKGK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RS20_NEOSM
Sequence: MANTASAKKMVRKIKRRTLVNKMRMSRIRTFVRKVRKAIAVGPKSAAAEALRVAQPEIHRGVTKGVLHKNRAARIVSRLSGHIKKMA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: GLO2_BRUA1
Sequence: MHRMEQRLEIEQFICRSDNYGVLIHDPESALTATIDAPDAYAIEAALERRGWTLDFIFTTHHHLDHVEGNEPLKEKFGVSIIGPEAEKAKIPGIDRTVKGGDEFTFGLFKVKVISTPGHTAGGISYYLPDAKVVFTGDTLFALGCGRLFEGTPATMFHSLEKLVALPGDTALYCGHEYTQNNARFALTIDPDNSALKERAKEIARLRAHERMTLPSTIALEMATNPFLRWHDRTIRARLGLQDAPDEAVFAEIRKRKDMF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: TRAN4_ECOLX
Sequence: MSSYSRAERAPWGDFPKVVRNGDLGSLTNEPEYQAAKQGDAEAALNLVERLISDDTVAQLKTLIGDDKPRIVPVLAVEAAGNNKIPAMMAVVLADRLGLEVETDIVQREKVARTGAGSDHRLAFNPTFEGEVIPGQKYIVVDDTLTMGGTIASLRGYIENNGGKVMAASVMTAHEGALDLAVKPKMLAGINEKHGPAMDAFWKETFGYGIDRLTQGEAGHLRAAPSVDAIRDRIAAARNEAVNRVGASRTATTARAGQQQSPAVKQSSGNSGEDLLQAAQEAETEQQALLESAPIEQTYQQTLALYVQAKHDQVERIEDRLEQLVDRQQARLQQLQSNAPGLLSLPRTKAAWQQQQAQQQARLQTLHTRLDMVREIKEGMGIHAPKIEELATRKMRADDPELAGDWDSMREAARRHQALMRKQEQEKKQAQERERGRSQSLGLSNKPS
What are the official names of this protein?
Protein TraN.
What is the protein family that this protein belongs to?
To H.influenzae HI_1407.
Protein: ERB1_LODEL
Sequence: MAKKEVSASKPGNTKKDNVLLKKRKQQAVEKEEAEKEKEEGVSEDEFNVQGLIDPESDSDDEGAAAAEEEEEEEEQQQDVKELDLDKGEVISSDSDAEDFDSEEELNKLLGEEDDPSDYSSVGFSDEPKEDGDEQDEQDAFAAADAATDDDAFGDVKLKNLSITDPSKLEVRTKFSDGTPRIIKPEIEPVYDSDDSDAENFNTIGNIPISAYEEMPHIGYDINGKRIMRPAKGSALDQLLESIDLPQGWTGLLDQNTGAPLKITDEELELIRKIQQQENTDENINPYEPLNDWFTKNQEVMPLTAVPEPKRRFVPSKHEAKRVMKIVKAIREGRILTPEKAKELKEKETEEMNYDLWQNESEVPDHIMNLRAPKLPPPTNEESYNPPEEYLLNEEEKQKWLEQDPVDRERNFIPQKYSSLRLVPGYQDSVRERFERSLDLYLAPRLRKNKLNIDPESLIPELPSPKDLRPFPIKCSTVYEGHTGKIRTLSIDPQGLWLATGSDDGSVRIWEVLTGRQVFKAQLVNKEHNGEDHIESLEWNPNAQTGILAVCAGENIYLLVPPIFGFEIENTGKLRIESGWGYDTFGNTKQDLKVKGEDTKGDLDDDEEEEEEEEDDDDDEGQGKVKAHNSTAPAKKDVAKWINPNSSQQAMGISAIIQCRRTVKKISWHRKGDYFVTVSPDSKNTAVLIHQLSKHLSQSPFRKSKGVIMDAKFHPFKPQLFVASQRQIKIYDLAQQTLLKKLLPGVRLLSTIDLHPRGDNLLAASYDKRVLWHDLDLAATPYKTLRYHEKAVRQIKYHKGSLPLFASASDDGIIHVFHGTVYDDLMTNPLLVPLKKLSGHKVINQIGVLDIVWHPKEAWLFSAGADGTARLWTT
What is the function of this protein?
Component of the NOP7 complex, which is required for maturation of the 25S and 5. 8S ribosomal RNAs and formation of the 60S ribosome.
What are the official names of this protein?
Ribosome biogenesis protein ERB1, Eukaryotic ribosome biogenesis protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat BOP1/ERB1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: CLPP_OSTTA
Sequence: MPIGVPKVAYRLPGESTPQWVDLYNRLYRERVLFLGSGLDDELANQLNGIMLYLSAEDASRSLFLYINSPGGSVTAGLSVFDIMNYVQASVTTIGIGFAASMASFILAGGERGSRIALPHCRVMIHQPQGGMEGQASEVVLEKEEIVRLRRLIGRLYVDLTGQPLSTIANDLDRDKYLSAREAREYGLVDLVATTETATV
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: TRPD_SHEB9
Sequence: MSTNPIQPLLDVLYQGKSLSREQTAELFSALIRGEMSEAAMAGMLVALKMRGETIDEISGAADAMRAAAKPFPCPERNNNPLHNGIVDIVGTGGDGFNTINISTTAAFVAAAAGAKVAKHGNRSVSSKSGSSDLLAQFGIDLTMSPETASRCLDALNLCFLFAPHYHGGVKHAVPVRQALKTRTLFNVLGPLINPARPEFMLLGVYSPELVLPIAKVLKALGTKRAMVVHGSGLDEVALHGNTQVAELKDGDIIEYQLTPADLGVPLAQISDLEGGEPAQNALITEAILKGNGTEAHANAVAINAGCALYVCGITDSVKAGTLLALATIQSGKAFELLSQLAKVSGEAHVNGQERGR
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: KCNE3_HUMAN
Sequence: METTNGTETWYESLHAVLKALNATLHSNLLCRPGPGLGPDNQTEERRASLPGRDDNSYMYILFVMFLFAVTVGSLILGYTRSRKVDKRSDPYHVYIKNRVSMI
What is the function of this protein?
Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits.  Modulates the gating kinetics and enhances stability of the channel complex.  Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 (PubMed:12954870).  Associated with KCNC4/Kv3. 4 is proposed to form the subthreshold voltage-gated potassium channel in skeletal muscle and to establish the resting membrane potential (RMP) in muscle cells.  Associated with KCNQ1/KCLQT1 may form the intestinal cAMP-stimulated potassium channel involved in chloride secretion that produces a current with nearly instantaneous activation with a linear current-voltage relationship.
What are the official names of this protein?
Potassium voltage-gated channel subfamily E member 3, MinK-related peptide 2, Minimum potassium ion channel-related peptide 2, Potassium channel subunit beta MiRP2.
What is the protein family that this protein belongs to?
Belongs to the potassium channel KCNE family.
Protein: QUEA_STRA1
Sequence: MNTNDFDFYLPEELIAQTPLEKRDASKLLVIDHKNKTMTDSHFDHILDELKPGDALVMNNTRVLPARLYGEKQDTHGHVELLLLKNTEGDQWEVLAKPAKRLRVGTKVSFGDGRLIATVTKELEHGGRIVEFSYDGIFLEVLESLGEMPLPPYIHEKLEDRDRYQTVYAKENGSAAAPTAGLHFTKELLEKIETKGVKLVYLTLHVGLGTFRPVSVDNLDEHEMHSEFYQLSKEAADTLNAVKESGGRIVAVGTTSIRTLETIGSKFNGELKADSGWTNIFIKPGYQFKVVDAFSTNFHLPKSTLVMLVSAFAGRDFVLEAYNHAVEERYRFFSFGDAMFVK
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_FRATN
Sequence: MIETDRIISANTAQTNDENVIDRAIRPKTLAEYEGQPAVREQMEIFIQAAKARKDALDHTLIFGPPGLGKTTLSNIIANEMGVELKQTSGPVLEKAGDLAALLTNLEENDVLFIDEIHRLSPVVEEILYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLVGATTRAGLLTSPLRDRFGIIQRLEFYSIDDLSKIVYRSAKLLNLDITTDGAMEIAKRSRGTPRIANRLLRRVRDYAQVKGSGVICFEIADKALSMLKVDPVGFDHMDHRYLLTLMEKFAGGPVGLDTMSAALSEEKGTIEDVIEPYLIQQGYIMRTARGRIATLLAYNHFKLKIPDNLSADQQQTLSI
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.