PharMolix/UniProtQA huggingface dataset:
Protein: KAIB_NOSS1
Sequence: MNKARKTYVLKLYVAGNTPNSVRALKTLKNILEQEFQGIYALKVIDVLKNPQLAEEDKILATPTLSKILPPPVRKIIGDLSDRERVLIGLDLLYEELTEEDWEAQSNL
What is the function of this protein?
A metamorphic protein which reversibly switches between an inactive tetrameric fold and a rare, thioredoxin-like monomeric fold (KaiB(fs)).  KaiB(fs) binds phospho-KaiC, KaiA and CikA.  KaiA and CikA compete for binding to KaiB(fs), and KaiB(fs) and SasA compete for binding to KaiC, thus the clock oscillator and output signal pathway are tightly coupled.
What are the official names of this protein?
Circadian clock oscillator protein KaiB.
What is the protein family that this protein belongs to?
Belongs to the KaiB family.
Protein: DYR_ENCCU
Sequence: MLALVVALASHRGIGNANALPWPRPLAADMAWFRTLSQSIPLISPDRIALAPSASNAVVMGRRTWDSIPSRFRPLANRINVVLSRGPARSTENTFFIQTFEALDSLPLPPSSMTFVIGGRDVYSLALESGRPHLIFATEVFESPECDVFFPHIDWASYEKRDITRDVSRLIDRTLASAFYSPETATFTENGTSFKMFLYTKPETR
What is the function of this protein?
Key enzyme in folate metabolism.  Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
What are the official names of this protein?
Dihydrofolate reductase.
What is the protein family that this protein belongs to?
Belongs to the dihydrofolate reductase family.
Protein: YJNJ_SCHPO
Sequence: MVKSCQKKPDIDEFFSFLQSAFHPLQTEELDTFVRNIFEYDDRGRLYNCLLTLVPYERLPIDAEDLSSRKTYARPVLIRQYRSLRFANKEENICRLTPNSAFVPVRDSAVASISTSKVQDFNSYATLTEAQKKTATPVEEKNFLNQIVIQCLDSLETDVETNTTHATLLAVDPTWLIRVSQHTCDRKAVANLCIQYGSQIFYDPSFRNAYELWSNPSVLLAFLKAQRVLVVSDIFTSSTLRSTQGTPMSFPNLALESADNVENVSKPINPRMERFSSEVKSSSILKQQIAAVVEKINYDIRPQRDQIPEENIVPRISYLTSTTTSTKSSPVPESTTTNTTEVLKELNDIQENKSRKNVEKATAATEEMLRGHHKPVEGTTATSEKESIKEEVDLEVNGDGKVEAEERIELESSDSEKELSELIDFLKREHPPEDTPEKRVKIKRIRTLLDTWQQEWRILNKAISNAESNSGRGQNSKTKTTSVNLSRNKRTRT
What are the official names of this protein?
Uncharacterized protein C24B10.19c.
Protein: HTPX_STREM
Sequence: MLYQQISQNKRRTVILLFAFFVLLVVIGAAAGYLLADSYQLGAAFALIIGAIYAFSMIFQSTSLVMGMNKAKEITVNDAPDFFHIVEDMALVAQIPMPKVFIIDDPSLNAFATGSSPQNAAVAATTGLLKVMNREELEAVIGHEVSHIRNYDIRISTIAVALASAVTLISSIGGRMMWYSGGRRRDDDRNDNGFGAIMLIFSILSLILAPLAASLVQLAISRQREYLADASSVELTRNPEGMIRALQKLSNSQPMTHPVDDASAALYINEPRKKEKLSALFSTHPPIEDRIERLKHM
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL34_CUPNH
Sequence: MKRTYQPSVTRRKRTHGFRVRMKTRGGRAVINARRAKGRKRLAI
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: LYRM7_XENLA
Sequence: MESKMKVLKLFRTLHRTRQCVFQNDHRALEAARQRINEEFKKNKRECSPAKISELLKFGTDVEILLRTSVVQGIHKDSDTLVLQARKDLLLDNIPFCDAPEKQT
What is the function of this protein?
Assembly factor required for Rieske Fe-S protein UQCRFS1 incorporation into the cytochrome b-c1 (CIII) complex.  Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane (By similarity).
What are the official names of this protein?
Complex III assembly factor LYRM7, LYR motif-containing protein 7.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: Y010_CLOAB
Sequence: MKKKVTIVTIILFLLVIVGSFGKVTDFIINLEWFKEIGYTSVYFTKLAAILKLMIPIFIIIYTGLWFYYKSIRKIIIKWNKVVEVNVKTEKLKKRVAIVIDVIASFFVAYFTSSVYWYRILQFTSGNSFNIKDPIFNLDVSFYVFRLPLIESLYGVMLLFLIFMAVLTVILYIVLSLRDRVYNRNIGGINISFKEFFKGLSDFAGRQFAIISGLIMFLVAVGYAIRSFNLVYSPRGVVYGGGYTDIHVSLVFYVIIIAAAIVSSVVIFTSIIKYKIKPIFVSIVAILILIIGQSITAEIVQNLIVKSNEKNLEAPYIKNNIEYTRKAFNIDKLSESNFPSSDSLTQADIDSNRDTVNNIKVNSVTPALEFYNQVQVVRYYYDFRDLDVDRYNIGGKYSEVFLAPREIDSKSLEGNADTWQNRHLIYTHGYGLVMSKVNSVTSEGQPNFVIKDIPPQNSTNLKITNPRIYYGEETDDYAIANNTLGEFDYPDGSKNKTNNYDGKGGIKANILNRLIFAINKRDSNFLLSENITSNSKILINRNIMDRLNKIAPFLSYDKDPYVVLSGGKLFWIVDAYTTSDRFPYSQPYNNVNYIRNSVKVVIDAVDGTTNFYIVDKNDPIANSYSKIFPGLFKDVSQVPKDIRSHFKYPEDLFSTQCNVLGKYHVTDTGVFYNSEDLWETAKNQKQINGEKGVNDASYFIMRLPGENKSEMVLMEYFNMKDKDNMSAIFGARMDGNNYGKLILYKLPTDKTVYSPYLFKQKLNQDPSISKEVSLWNTQGSSVQFGDTSIIPIKNSLLYVEPVYLRAQGKNSMPEVKRVIVSFGNKMVMANSIDEALNQIFNNSSNNQSETRTETGGTSTDSSNNKDKLKQAQDLYNQAVDAQKNGDWSKYGDYINKLGKTLDELNK
What are the official names of this protein?
UPF0182 protein CA_C0010.
What is the protein family that this protein belongs to?
Belongs to the UPF0182 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DEF1_VIBPA
Sequence: MSVLQVLTFPDDRLRTVAKPVDAVTPEIQKIVDDMIETMYDEEGIGLAATQVDIHKRIVVIDISETRDEPMVLINPEILEKRGEDGIEEGCLSVPGARALVPRAAEVTVKALDRDGKEFTFEADDLLAICVQHELDHLQGKLFVDYLSPLKRKRIQDKLAKIKRFNEKQQNA
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase 1, PDF 1, Polypeptide deformylase 1.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: SP15_HEMPU
Sequence: AVQLVFTDAEKAEFKFGFKSKDGDNSITAKELGEFLESAGKSFSEEQLAQMISDVDTDKSGTIEFSEMLMGIAEKMMKWTWKKSHFQKAFDDMDKDGNGVLSPEELHLAMSTRIEPPMSKEAIDAIIAKADCDGDGKINRKEFVKLIKSS
What is the function of this protein?
May play an important role in mitosis of sea urchin egg.  May function as a Ca(2+)-dependent intracellular modulator of microtubule assembly.
What are the official names of this protein?
15 kDa calcium-binding protein, CABP.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Note=Nuclei of fertilized eggs and mitotic apparatus of dividing eggs.
Protein: UNC47_CAEEL
Sequence: MASNRFQNLQNWTNKHVFSNSLDYWNQELNEVPSYQNQPQTGESGSNPPPHDRLEPIQESVVSEQPQKDDINKQEEAKDDGHGEASEPISALQAAWNVTNAIQGMFIVGLPIAVKVGGWWSIGAMVGVAYVCYWTGVLLIECLYENGVKKRKTYREIADFYKPGFGKWVLAAQLTELLSTCIIYLVLAADLLQSCFPSVDKAGWMMITSASLLTCSFLDDLQIVSRLSFFNAISHLIVNLIMVLYCLSFVSQWSFSTITFSLNINTLPTIVGMVVFGYTSHIFLPNLEGNMKNPAQFNVMLKWSHIAAAVFKVVFGMLGFLTFGELTQEEISNSLPNQSFKILVNLILVVKALLSYPLPFYAAVQLLKNNLFLGYPQTPFTSCYSPDKSLREWAVTLRIILVLFTLFVALSVPYLVELMGLVGNITGTMLSFIWPALFHLYIKEKTLNNFEKRFDQGIIIMGCSVCISGVYFSSMELLRAINSADS
What is the function of this protein?
Involved in the uptake of GABA into the synaptic vesicles.
What are the official names of this protein?
Vesicular GABA transporter, Uncoordinated protein 47, Protein unc-47.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Protein: H32_MOUSE
Sequence: MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.2, H3-clustered histone 13, H3-clustered histone 14, H3-clustered histone 15, H3-clustered histone 2, H3-clustered histone 3, H3-clustered histone 4, H3-clustered histone 6, H3-clustered histone 7.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: SYDND_SYNE7
Sequence: MRTHYCGELRAEQVGTSVTLYGWVDRRRDHGGVIFVDLRDRTGTVQIVSDPERTPESYHQAEGLRNEYVVKITGRVSGRPAESLNPKLPTGEVEIYADRIEILNAVRRQLPFQVSSADEETVREDLRLRYRYLDLRRDRMNRNLQLRHQVVKAIRRFLEDEEQFIEIETPVLTKSTPEGARDYLVPSRVNPGEWFALPQSPQLFKQLLMVSGFDRYYQIARCFRDEDLRADRQPEFTQLDMEMSFLSQEEIIDLNERLIAHIFKTVKGIELPRPFPRLTYAEAMDRYGSDRPDTRFGLELVDVSDVVADMGFKVFSGAVKSGGKVKILPIPDGNDRISNVRIKPGGDIFKEATEAGAAGLAYIRVRENGEIDTIGAIKDNLSDEQKAEILRRTQAQPGTLLLFGAGSTDIVNKSLDRVRQFLGKELGLIDPEALNLLWVVDFPMVEWNADEKRYEALHHPFTAPNPQDLEDLTTARAQAYDIVLNGLEIGGGSLRIYQRDIQERVFETIGLSHEEAQAKFGFLLEAFDFGTPPHGGIAYGLDRLVMLLTGEESIRDAIAFPKTQQARCLLTEAPADVSDRQLKELYVASTWQPPIKERD
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTH_METNO
Sequence: MSSVAITPGCVPLSGWRAILAGAAIRLDESCRPAIARAAEAVAAIVTRAEPVYGINTGFGKLATVRIDAADLATLQRNIVLSHAAGTGEPMPVAVARLMMALKLASLGQGASGVRPETVALLEAMLARGVTPLVPAQGSVGASGDLAPLAHMTAAMIGVGACIDEAGTRIPAAEALSRVGLEPLTLGPKEGLALLNGTQFSTAYALAGLFGAEDLLRAALVAGALSVDAARGSDTPFDPRIHALRRHRGQIETARALRDLLSGSAIRASHLVGDERVQDPYCLRCQPQVMGAALDLLRQAAATLETEANGVSDNPLVFPETGEALSGGNFHAEPVAFAADMIALALCEIGALSERRIALLVDPALSSGLPAFLTPRPGLNSGFMIPQVTAAALVSENKQRAHPASVDSIPTSANQEDHVSMAAHGARRLLPMVENAMAVIAIELLAAAQGCDFLAPLRSSEPLERVRARLRAAVPRLDEDRYFHPDLAAAAALVRGGAVVEAAGVGLPGVSGGVA
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIA_HYDCU
Sequence: MIHKQQLQAYLQLTRIDRPIGIYLVLWPALWALWLAADGMPPMSILIIFILGAVIMRSAGCVINDYADRHFDGYVTRTCARPLATGQLTERQALKFFFVLCLLAFGLVLFLNPFTILLSLGAVGLAILYPFMKRHTFWPQAFLGAAFAWAIPMAFAAIQNQVPWQAWVIFGVTLVWALVYDTAYAVADKEDDVKLGIKSTAILFGDRVQEIIGFFQAIMLLGFLWIGDLFGLSWLYYGSVLIAAGFFVYHQYLLSFDQPQKAFKAFLNNHWVGLVILIGIMLDTL
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MATRX_BEFVB
Sequence: MLTLFKKGKPKGGSVDDRNSSYRESDPMLVWGTAPPAYLDVYHDERDKNELQFNTKSYLIQANLEVISSKPIERTTEMLKVLDVMVDEYDGSYLSKALIITSYLTIGTHLRRMMSSVKNNHKYNNGFTEVIEFTGTAEIHPRDQEIKYNKYLMTSHMGEPVSISYQFSGKKSKRRGKNILDAYNLELGNGSKPPDLKDLLESYEINLCYNLKGEHGFTNLVKS
What is the function of this protein?
Plays a major role in assembly and budding of virion.  Completely covers the ribonucleoprotein coil and keep it in condensed bullet-shaped form.  Inhibits viral transcription and stimulates replication (By similarity).
What are the official names of this protein?
Matrix protein.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein. Host endomembrane system; Peripheral membrane protein.
Protein: PANB_HERA2
Sequence: MRTQLSDIQRMKDRGERLVMVTAYDYTSAQLVDRTDIPLILVGDSLGMVIQGNSSTVPVTIDEMVYHTKAVMRGSSKALVVGDLPFLSYTSPEQAIQNAGKLMQIGGCGAVKLEGGVNLAPTVRRLVDLGIPVMGHLGFTPQSVNQIGMRVQGKTVAHARQLLDDALALEAAGAFAIVLELIPAALAKAITARLHIPTIGIGAGVGCDGEVQVWHDILGLYSDHLPRHTKRYADLGSTIEQALTQYAHEVRERSFPTAANSSVIDANTLAEALGEQTVSVGASAKVAV
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: B2AV_RANAR
Sequence: GLMSVLKKAGKHVAKNVAVSLMDSLKCKISGGC
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Brevinin 2AV.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
Protein: GSA_XANAC
Sequence: MNHSRSHALFAQAQTLLPGGVNSPVRAFKSVGGEPFFVARADGPYLFDVDDNRYIDYVGSWGPMIAGHNHPAVREAVEQSIRNGLSFGAPCAAEVAMAQTITRLVPSCEMVRMVNSGTEATLSAVRLARGATGRNRIIKFEGCYHGHGDSFLVKAGSGMLTLGVPTSPGVPAGLSELTATLSFNDFEGATALFDEIGAEVAAVIIEPVVGNANCIPPQAGYLQHLRTLCTRHGALLIFDEVMTGFRVALGGAQAHYGVTPDLTTFGKIIGGGMPVGAYGGRRDLMEQVAPAGPIYQAGTLSGNPVAMAAGLAMLELVQEPGFHTRLSEATSMLCEGLEDAARAAGIAVTTNQVGGMFGLFFTDDIVESYAQATACDITTFNRFFHAMLQQGVYLAPSAYEAGFMSSAHDEAVIDATLAAAREAFAEVAR
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRP2_RAT
Sequence: MASTLDLDKGCTVEELLRGCIEAFDDSGKVRDPQLVRMFLMMHPWYIPSSQLASKLLHFYQQSRKDNSNSLQVKTCHLVRYWVSAFPAEFDLNPELAEQIKELKALLDQEGNRRHSSLIDIESVPTYKWKRQVTQRNPVEQKKRKMSLLFDHLEPMELAEHLTYLEYRSFCKILFQDYHSFVTHGCTVDNPVLERFISLFNSVSQWVQLMILSKPTATQRALVITHFVHVAEKLLQLQNFNTLMAVVGGLSHSSISRLKETHSHVSPDTIKLWEGLTELVTATGNYSNYRRRLAACVGFRFPILGVHLKDLVALQLALPDWLDPGRTRLNGAKMRQLFSILEELAMVTSLRPPVQANPDLLSLLTVSLDQYQTEDELYQLSLQREPRSKSSPTSPTSCTPPPRPPVLEEWTSVAKPKLDQALVAEHIEKMVESVFRNFDVDGDGHISQEEFQIIRGNFPYLSAFGDLDQNQDGCISREEMISYFLRSSSVLGGRMGFVHNLQESNSLRPVACRHCKALILGIYKQGLKCRACGVNCHKQCKDRLSVECRRRAQSVSLEGSAPSPSPTHTHHRAFSFSLPRPGRRSSRPPEIREEEVQTVEDGVFDIHL
What is the function of this protein?
Functions as a calcium- and DAG-regulated nucleotide exchange factor specifically activating Rap through the exchange of bound GDP for GTP.  May also activate other GTPases such as RRAS, RRAS2, NRAS, KRAS but not HRAS.  Functions in aggregation of platelets and adhesion of T-lymphocytes and neutrophils probably through inside-out integrin activation.  May function in the muscarinic acetylcholine receptor M1/CHRM1 signaling pathway.
What are the official names of this protein?
RAS guanyl-releasing protein 2, Calcium and DAG-regulated guanine nucleotide exchange factor I, CalDAG-GEFI.
What is the protein family that this protein belongs to?
Belongs to the RASGRP family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein. Synapse, synaptosome. Cell projection, ruffle membrane; Peripheral membrane protein. Note=Found both in the cytosol and associated with membranes (By similarity). Enriched at juxtamembrane areas and membrane ruffles (By similarity). Localizes to the cell bodies and axons of striatal neurons.
Protein: SYM_BUCAI
Sequence: MSSVFRKILVTCALPYANGSIHIGHMLEHIQADIWVRYHRMRGHEVWFVSADDAHGTAIMLKAQDLEISPNKLIKNIRIEHQIDFSNFKISHDNYYSTHSLENLYLSRKIFTCLNEKGLIKEKKIFQLYDTVKKIFLPDRFIKGTCPICKSKNQYGDNCEICSATYEPTDLINPISVISGKKPILKNTKHLYFDLPSFTNMLKKWIHSGVLEESVIKKTEEWFKVGLKSWAISRDAPYFGFKIPNYPNKYFYVWLDAPIGYISAFKNLCFKSKKLNFNELWNQNSNYELYHFIGKDIIYFHTLFWPAILEAVSFRQPSGIFVHGHLTMNGLKLSKSRGALIKASDWIQYFDSDSLRYYYASKLSNKTHDIEINLEDFIQKINSDIVNKLVNLAARNASFINKYFNGYLSDKLSNIKLYKYFVNTSSSIEDFFENREFSFIVKESMRLLDVANQYINEKKPWKIKRTEENIRELQNICTMGINLFRIIMIFLKPIVPDLAIKTESFLISKLTWDGIKKPLLSHQINKFFPLYKRIDVEKMFEFMNICR
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBIA_NOCFA
Sequence: MTGQHADIAPATGPRIVVLVGGVGGARFLQGVRELLPDAEVSAIVNVGDDVWMHGLRICPDLDTCMYTLGGGIDTERGWGRVGETWHAKEELAAYHAKPDWFGLGDRDLATHLIRTEMLRAGYPLSAVTEALCNRWQPGVKLIPATDDRCETHVVVTDPENPGERRAIHFQEWWVRYRANVETHGFATIGADEAKPAPNVIDLIESADAVLLAPSNPVVSIGAILAVPGIRGALRTTRAKVIGVSGVIDGKPLRGMADECLSVIGVETTAEAVGRHYGARSATGILDGWLIHTTDTAEVPGVEVRSVPLLMTDPPTTAEIVREALDLAGVKW
What is the function of this protein?
Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
What are the official names of this protein?
Phosphoenolpyruvate transferase, EPPG:FO PEP transferase.
What is the protein family that this protein belongs to?
Belongs to the CofD family.
Protein: KS6C1_MOUSE
Sequence: MTSPWGHSADLARFYTVTEPQRHPRGYTVYKVTARVVSRRNPEDVQEIIVWRRYSDFKKLHRELWQIHRNAFRHSELFPPFAKGTVFGRFDKTVIEERRQCAEDLLQFSANIPALYNSRQLQDFFKGGVISDGSELIGPAEAYPDSPANAFPECGTEGFSSDSDLLSLTVDADSLAEVDDGMASRQGSPSRTFGLSLSTDSSAVGAVASDSEPSRVEDRESRSLFPSSLKPRLGRRDYLEKAGELIKLALKKEEEDDYEAASDFYRKGVDLLLEGVQGESSPTRREAVKRRTAEYLMRAESICSLRAAPQLHTGPQPPGSLSSRPPWSLRSPAEELKAFRVLGVIDKVLLVMDTRTEQTFILKGLRKSSECSRNRKTIIPRCVPNMVCLHTYIISEESVFLVLQRAEGGKLWSYISKFLNRSSQESLDIKEGRPSMPPRVCLQQPSASPQGGSSFESRGSDTGSMLKALPLKTSLTPSSQDDSNQEDDGQPSSPKWLDSGSSSEDECTAGYLTLCNEYGQEKMDLVSLSEESVMQPEGDKADTQAVSSPASLATGSVSPSTHLRVFSGGEDLEAVSSPPTSESLSRSKNSPMEFFRIDSKDSTSELLGLDFGEKLHSLKPEPLKALFTLEDGDSPSQSLDPGESKRESEAQDSVSRGSDDSVPVISFKEAAAEAISGAEEGRPDLLVNLPGELQPTKEASAMDPKFSQASAGRLDSKLLEAPDVLCLRLSSEQCHGLGPEGPEELSDPTEFCPGGVIPEHDAQADPGVLFEAAVDHRSSPDQFLFSSLRSESDRLGQVEVVVTAQALQESLFHISSPCSGANKEHSAYADTATSEEVLLFTEPTKEEANSLFQRGSEAQERGVGAGEADKEIHQIFEDLDKRLAASSRFFIPEGCIQRWAAEMVVALDALHREGIVCRDLNPNNILLNDGGHIQLTYFSRWSEVEDSCDSDAVARMYCAPEVGAVTEETEACDWWSLGAVLFELLTGKTLVECHPAGINTHTTLNMPGCVSEEARSLIQQLLQFNPMERLGAGVAGVEDIKSHPFFTPVDWAELTR
What is the function of this protein?
May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell.  Plays a role in the recruitment of PRDX3 to early endosomes.
What are the official names of this protein?
Ribosomal protein S6 kinase delta-1, S6K-delta-1, 52 kDa ribosomal protein S6 kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. S6 kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Membrane. Early endosome.
Protein: RL27_CLOB6
Sequence: MLVMNLQLFAHKKGVGSSKNGRDSEAKRLGVKCSDGQFVLAGNILVRQRGTKIHPGLNVGRGGDDTLFAKIDGVVKYERLGRDKKKASVYPVEVEKVVAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: SEPF_CLOBL
Sequence: MSGKILDKMAGLLGLEDDLEEDLEEVEEETAEEEVTPLISSNTKRNNKVVSIHTAVSAKVKIIKPCSYEEAVDICDELKNRKIIIVNTTDLETKIAQRLLDFMGGASYALGGSLEEVEKSVYILAPSTVEVTNELKSQLISSKGIFNWNK
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: GCC1_ARATH
Sequence: MWPLCFLLNKLLRVEERNQGILDGNGDSTFPKYCLFDDPLVSDGKYRDAGLPSSSHMDVPHVHQLASWDCGLACVLMVLRASGIASCTLEDLAEICSTNSIWTVDLAYLLQKFCVEFSYYTITFGANPNYSIEEFYKEQLPEDLVRVDLLFRKAHESGIIIQCRSVSIHEISCLLLSGNYIAIALVDQDKLSKSWLEEVLVSGLHSSNSCYTGHYVVICGYDAVRDEFEIRDPASSKIHERISSKCLENARKSFGTDEDLLLINLENMRNQNGY
What is the function of this protein?
Magnesium-dependent guanylyl cyclase that catalyzes the formation of guanosine 3',5'-cyclic monophosphate (cGMP) from guanosine 5'-triphosphate (GTP) (PubMed:12482758).  Can also use ATP as substrate with a low activity (PubMed:12482758).
What are the official names of this protein?
Guanylyl cyclase 1, AtGC1.
Protein: RS19_CORA7
Sequence: MPRSLKKGPFVDEHLLNKVDAQNEAGTKQVIKTWSRRSTILPDFIGHTFAVHDGRKHVPVFVEDSMVGHKLGEFAPTKTFKGHVKDDKKGRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: DEFI8_HUMAN
Sequence: MAILSLRAPGPWQAMQVWADRTLLTPHTGVTSQVLGVAAAVMTPLPGGHAAGRTREARWDAMEYDEKLARFRQAHLNPFNKQSGPRQHEQGPGEEVPDVTPEEALPELPPGEPEFRCPERVMDLGLSEDHFSRPVGLFLASDVQQLRQAIEECKQVILELPEQSEKQKDAVVRLIHLRLKLQELKDPNEDEPNIRVLLEHRFYKEKSKSVKQTCDKCNTIIWGLIQTWYTCTGCYYRCHSKCLNLISKPCVSSKVSHQAEYELNICPETGLDSQDYRCAECRAPISLRGVPSEARQCDYTGQYYCSHCHWNDLAVIPARVVHNWDFEPRKVSRCSMRYLALMVSRPVLRLREINPLLFSYVEELVEIRKLRQDILLMKPYFITCREAMEARLLLQLQDRQHFVENDEMYSVQDLLDVHAGRLGCSLTEIHTLFAKHIKLDCERCQAKGFVCELCREGDVLFPFDSHTSVCADCSAVFHRDCYYDNSTTCPKCARLSLRKQSLFQEPGPDVEA
What is the function of this protein?
Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts.  Involved in bone resorption.
What are the official names of this protein?
Differentially expressed in FDCP 8 homolog, DEF-8.
What is the protein family that this protein belongs to?
Belongs to the DEF8 family.
Protein: SYI_LEGPA
Sequence: MAEYKDTLNLPNTSFPMKASLSVREPEMLADWQAKGIYQKIRKARVGSKRFILHDGPPYANGHLHCGHALNKILKDIIIKSKTFSGFDAPFVPGWDCHGLPIELNVEKKVGKAGSKISPREFRAKCREYAASQIDIQRDEFQRLGVLGDWYNPYVTMDYHYEANIVRALGLMIKNGHLQQGFKPVHWCIDCGSALAEAEVDYEDKTSPSIDVAFSAVNPSEFLNCFETQPAVKPLILPIWTTTPWTLPANEAVCLHPEIDYALIDAGNSYYIVATDLVESVMARYGISHYKTSGSAKGRVFEHFKLQHPFYKRQVPVVLAEHVTTESGTGCVHTAPAHGPDDYLVGQSYQLPLINPVMANGCFAENVELFAGISVLKANETILAVLSERNVLLASESIRHSYPHCWRHKSPMIFLATPQWFISMDKSNLRQAIINEIDKVNWVPDWGKARISNMVENRPDWCISRQRSWGTPMPLFVHKTTRELHPDTLELIERVAVMIEKSGIDAWFDLDSSELLGDDAKHYDKITDTMDVWLDSGISHYSVLKHNNDLDFPADVYFEGSDQHRGWFNSSLTTAVAMYGVAPYKTVLTHGYTVDAEGKKLSKSKGNYVALDKLVNQHGADILRLWVASTDYRHEVSISEEIIKRNADAYRRIRNTARFLLANLFDFNPASDCIEAKELLELDRWALKRCQLLQEEIITAYENYHFHLIYQKIHNFCAVDMGSFYLDLIKDRQYTTAKDSIARRSCQTAMYHMVKAFTIWLAPILSFTAEEIWQTIPGNNSESIFIEHWYDAWPIIDAVNMEDWEQLHIVRDEVNKALEETRQRGEIGSALAAEVTVYADAKALPKLTRLGEELRFLFITSEAKACPISQSPKGLAVTDCGVSIQVTASAHEKCARCWHRREDVGQNQEHPELCLRCVGNISGYHEERLYI
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.