PharMolix/UniProtQA huggingface dataset:
Protein: CRX_HUMAN
Sequence: MMAYMNPGPHYSVNALALSGPSVDLMHQAVPYPSAPRKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQAKARPAKRKAGTSPRPSTDVCPDPLGISDSYSPPLPGPSGSPTTAVATVSIWSPASESPLPEAQRAGLVASGPSLTSAPYAMTYAPASAFCSSPSAYGSPSSYFSGLDPYLSPMVPQLGGPALSPLSGPSVGPSLAQSPTSLSGQSYGAYSPVDSLEFKDPTGTWKFTYNPMDPLDYKDQSAWKFQIL
What is the function of this protein?
Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes.  Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription.  Essential for the maintenance of mammalian photoreceptors.
What are the official names of this protein?
Cone-rod homeobox protein.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RUTC_KLEP3
Sequence: MPKQVIIPPGTTTPIAPFVPGTLADGVVYVSGTLPFDKQNNVVHIGDPKAQTRHVLETIKSVIETAGGSMADVTFNSIFITDWTNYAAINEVYAEFFPGDKPARFCIQCGLVKPDALVEIASVAHIGAPT
What is the function of this protein?
Involved in pyrimidine catabolism.  Catalyzes the deamination of 3-aminoacrylate to malonic semialdehyde, a reaction that can also occur spontaneously.  RutC may facilitate the reaction and modulate the metabolic fitness, rather than catalyzing essential functions.
What are the official names of this protein?
3-aminoacrylate deaminase RutC, 3-AA deaminase.
What is the protein family that this protein belongs to?
Belongs to the RutC family.
Protein: COAA_LACPL
Sequence: MEDQMNYYRFSREQWKQFYRNNQHQVPLTAANLHEIEAFNDRISLDDVRDIYMPFAHLLQAKYEHYLSWRETESVFLHRQNRQSPFIIGVSGSVAVGKTTTARLLEILFKYLYPDRRTQLITTDGFLYPNAELKKMQLMERKGFPESYDMTRLIQFLNDVKSGKPLAKAPVYSHQTYDIVPNRFDVITHPDILIIEGINVLQLPSNQAIYISDFTDFSVYVDADADLIEDWYLERFKALMKTAFQDPTNYFYPWAIGDPKDAMAMAERVWEEVNLKNLNDYILPTRNRADLILHKVAHHVIDAVYFRKY
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MPPA_YEAST
Sequence: MLRNGVQRLYSNIARTDNFKLSSLANGLKVATSNTPGHFSALGLYIDAGSRFEGRNLKGCTHILDRLAFKSTEHVEGRAMAETLELLGGNYQCTSSRENLMYQASVFNQDVGKMLQLMSETVRFPKITEQELQEQKLSAEYEIDEVWMKPELVLPELLHTAAYSGETLGSPLICPRELIPSISKYYLLDYRNKFYTPENTVAAFVGVPHEKALELTEKYLGDWQSTHPPITKKVAQYTGGESCIPPAPVFGNLPELFHIQIGFEGLPIDHPDIYALATLQTLLGGGGSFSAGGPGKGMYSRLYTHVLNQYYFVENCVAFNHSYSDSGIFGISLSCIPQAAPQAVEVIAQQMYNTFANKDLRLTEDEVSRAKNQLKSSLLMNLESKLVELEDMGRQVLMHGRKIPVNEMISKIEDLKPDDISRVAEMIFTGNVNNAGNGKGRATVVMQGDRGSFGDVENVLKAYGLGNSSSSKNDSPKKKGWF
What is the function of this protein?
Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins.
What are the official names of this protein?
Mitochondrial-processing peptidase subunit alpha, Alpha-MPP, Inactive zinc metalloprotease alpha, Matrix processing peptidase, MPP, Mitochondrial assembly protein 2, Mitochondrial import function protein 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M16 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: IL2RG_HUMAN
Sequence: MLKPSLPFTSLLFLQLPLLGVGLNTTILTPNGNEDTTADFFLTTMPTDSLSVSTLPLPEVQCFVFNVEYMNCTWNSSSEPQPTNLTLHYWYKNSDNDKVQKCSHYLFSEEITSGCQLQKKEIHLYQTFVVQLQDPREPRRQATQMLKLQNLVIPWAPENLTLHKLSESQLELNWNNRFLNHCLEHLVQYRTDWDHSWTEQSVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEWSHPIHWGSNTSKENPFLFALEAVVISVGSMGLIISLLCVYFWLERTMPRIPTLKNLEDLVTEYHGNFSAWSGVSKGLAESLQPDYSERLCLVSEIPPKGGALGEGPGASPCNQHSPYWAPPCYTLKPET
What is the function of this protein?
Common subunit for the receptors for a variety of interleukins.  Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15 (PubMed:15123770).
What are the official names of this protein?
Cytokine receptor common subunit gamma, Interleukin-2 receptor subunit gamma, IL-2 receptor subunit gamma, IL-2R subunit gamma, IL-2RG, gammaC, p64.
What is the protein family that this protein belongs to?
Belongs to the type I cytokine receptor family. Type 5 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell surface.
Protein: NOSO_STAAR
Sequence: MLFKEAQAFIENMYKECHYETQIINKRLHDIELEIKETGTYTHTEEELIYGAKMAWRNSNRCIGRLFWDSLNVIDARDVTDEASFLSSINYHIAQATNEGKLKPYITIYAPKDGPKIFNNQLIRYAGYDNCGDPAEKEVTRLANHLGWKGKGTNFDVLPLIYQLPNESVKYYEYPTSLIKEVPIEHDHYPKLRKLNLKWYAVPIISNMDLKIGGIVYPTAPFNGWYMVTEIGVRNFIDDYRYNLLEKVADAFEFDTLKNNSFNKDRALVELNYAVYHSFKKEGVSIVDHLTAAKQFELFERNEAQQGRQVTGKWSWLAPPLSPTLTSNYHHGYDNTVKDPNFFYKKKKSNANQCPFHH
What is the function of this protein?
Catalyzes the production of nitric oxide.
What are the official names of this protein?
Nitric oxide synthase oxygenase, NOSoxy-like protein, SANOS.
What is the protein family that this protein belongs to?
Belongs to the NOS family. Bacterial NOS oxygenase subfamily.
Protein: MEKB_PSEVE
Sequence: MNSYYTEENHGPFELINIGPLPLEEGRCMPECLLAVAVHGALNADKSNAILVPTWYSGTSKAMEQIYIGEGRALDPSKYCIIVVNQIGNGLSSSASNTGGSLAGPGFANVRIGDDVSAQHTLLTEYFGIESLALVVGGSMGAQQTYEWAVRYPDFVKRAAAIAGTARNSEHDFLFTEILIEAITTDPAFQAGLYRSSSAVAAGLERHAKLWTLMGWSPEFFRTGRHKALGFESMQMFVDGFMKRYFAPMDPNNLLTMAWKWQRGDVSRHTGGDLAKALGRIKAKTYVMPISHDQFFTVDDCLSEQKMIPNSEFRPLRSIDGHLGLFGTDAQMLDQLDAHLAELLSSPAY
What is the function of this protein?
Esterase that catalyzes the hydrolysis of ethyl acetate (PubMed:17351032).  Involved in the degradation of short chain methyl ketones (MEK) such as 2-butanone and 2-hexanone (PubMed:17351032).  In vitro, can also hydrolyze vinyl acetate, 4-nitrophenyl acetate, methyl acetate, propyl acetate, benzyl acetate and methyl propionate (PubMed:17351032).  The highest activities are obtained with acetic acid esters, but the alcohol group also plays an important role, as compounds with two carbon atoms in the alcohol moiety, i. e. , vinyl and ethyl acetate, are by far the preferred substrates (PubMed:17351032).
What are the official names of this protein?
Ethyl acetate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Acetyl esterase family.
Protein: RL33_CHLCH
Sequence: MAKGKENRIVITLECTEAKKEGKPVSRYTTTKNKKNTTERLVLKKYNPNLQRHTLHKEIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: MYO10_HUMAN
Sequence: MDNFFTEGTRVWLRENGQHFPSTVNSCAEGIVVFRTDYGQVFTYKQSTITHQKVTAMHPTNEEGVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQYSRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQQSLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGRIVDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPENYHYLNQSGCVEDKTISDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEFITAGGAQVSFKTALGRSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWVIKKINSRIKGNEDFKSIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLEQLEYSREGLVWEDIDWIDNGECLDLIEKKLGLLALINEESHFPQATDSTLLEKLHSQHANNHFYVKPRVAVNNFGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIYDLFEHVSSRNNQDTLKCGSKHRRPTVSSQFKDSLHSLMATLSSSNPFFVRCIKPNMQKMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLALPEDVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSSELAESACEEKPNFNFSQPYPEEEVDEGFEADDDAFKDSPNPSEHGHSDQRTSGIRTSDDSSEEDPYMNDTVVPTSPSADSTVLLAPSVQDSGSLHNSSSGESTYCMPQNAGDLPSPDGDYDYDQDDYEDGAITSGSSVTFSNSYGSQWSPDYRCSVGTYNSSGAYRFSSEGAQSSFEDSEEDFDSRFDTDDELSYRRDSVYSCVTLPYFHSFLYMKGGLMNSWKRRWCVLKDETFLWFRSKQEALKQGWLHKKGGGSSTLSRRNWKKRWFVLRQSKLMYFENDSEEKLKGTVEVRTAKEIIDNTTKENGIDIIMADRTFHLIAESPEDASQWFSVLSQVHASTDQEIQEMHDEQANPQNAVGTLDVGLIDSVCASDSPDRPNSFVIITANRVLHCNADTPEEMHHWITLLQRSKGDTRVEGQEFIVRGWLHKEVKNSPKMSSLKLKKRWFVLTHNSLDYYKSSEKNALKLGTLVLNSLCSVVPPDEKIFKETGYWNVTVYGRKHCYRLYTKLLNEATRWSSAIQNVTDTKAPIDTPTQQLIQDIKENCLNSDVVEQIYKRNPILRYTHHPLHSPLLPLPYGDINLNLLKDKGYTTLQDEAIKIFNSLQQLESMSDPIPIIQGILQTGHDLRPLRDELYCQLIKQTNKVPHPGSVGNLYSWQILTCLSCTFLPSRGILKYLKFHLKRIREQFPGSEMEKYALFTYESLKKTKCREFVPSRDEIEALIHRQEMTSTVYCHGGGSCKITINSHTTAGEVVEKLIRGLAMEDSRNMFALFEYNGHVDKAIESRTVVADVLAKFEKLAATSEVGDLPWKFYFKLYCFLDTDNVPKDSVEFAFMFEQAHEAVIHGHHPAPEENLQVLAALRLQYLQGDYTLHAAIPPLEEVYSLQRLKARISQSTKTFTPCERLEKRRTSFLEGTLRRSFRTGSVVRQKVEEEQMLDMWIKEEVSSARASIIDKWRKFQGMNQEQAMAKYMALIKEWPGYGSTLFDVECKEGGFPQELWLGVSADAVSVYKRGEGRPLEVFQYEHILSFGAPLANTYKIVVDERELLFETSEVVDVAKLMKAYISMIVKKRYSTTRSASSQGSSR
What is the function of this protein?
Functions as a dominant-negative regulator of isoform 1, suppressing its filopodia-inducing and axon outgrowth-promoting activities.  In hippocampal neurons, it increases VASP retention in spine heads to induce spine formation and spine head expansion (By similarity).
What are the official names of this protein?
Unconventional myosin-X, Unconventional myosin-10.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell projection, lamellipodium. Cell projection, ruffle. Cytoplasm, cytoskeleton. Cell projection, filopodium tip. Cytoplasm, cell cortex. Cell projection, filopodium membrane; Peripheral membrane protein. Note=May be in an inactive, monomeric conformation in the cytosol. Detected in cytoplasmic punctae and in cell projections. Colocalizes with actin fibers. Undergoes forward and rearward movements within filopodia. Interacts with microtubules.
Protein: F7ODM_OCIBA
Sequence: MRITLQYIKLESKNTKERDMAESKAIGRSLEVPNVQELAKGKLASVPARYVRYSDRENTTLPPLTQIPVIDMQALLHPNSFEAELNSLHKACKQWGFFQLINHGVEAAVMEKMKLEMQEFFNLPLEEKQKFRQSADDMEGYGQSFVVSDEQKLDWADGFSVISLPTYLRKPHLIPKLPAPFRDAIDAYGAQLKELAIKILGFMAEALGMDPHEMTALFEEGIQALRMNYYPPCPQPEMVSGLCPHSDAGGLTILMQVNEVEGLQVRKDGGWVPVSPLPDAFIINLGDILEIVTNGEYFSVEHQATVNGDKERLSVAAFLNPKMEDNIGPAASFISGETPAKFKTITAAEYFKGLFSKELDGKSYLDLMRIQN
What is the function of this protein?
Oxoglutarate-dependent dioxygenase (2-ODD) acting as a flavonoid 7-O-demethylase involved in the biosynthesis of polymethoxylated flavonoids natural products such as nevadensin and salvigenin, aroma compounds which contribute to the flavor of sweet basil, and exhibit pharmacological activities such as anti-allergic, anti-oxidant, antibacterial, anti-proliferative, and anti-inflammatory effects (PubMed:25378691).  Catalyzes the 7-O-demethylation of methoxylated flavones; mediates the conversion of 8-hydroxysalvigenin (8-OH-SALV) to pilosin (PIL) and of gardenin B (GARD B) to nevadensin (NEV) (PubMed:25378691).
What are the official names of this protein?
Oxoglutarate-dependent flavonoid 7-O-demethylase 1, ObF7ODM1, 2-oxoglutarate-dependent dioxygenase 1, ObDIOX1, 8-hydroxysalvigenin 7-O-demethylase, Gardenin B 7-O-demethylase.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: TILS_RUEPO
Sequence: MLLTIGAQDLVNHLRAQFSAQPPRRLGVAVSGGGDSVALMHLLARCFPRGEVKLCVATVDHGLRSESASEAALVARQAAGLGLPHETLLWTGWTGEGNLQDQARRARYGLLTDWALRNRVTTVALAHTADDQAETLLMRLGRSAGVSGLAAMAPRRMQDGVVLVRPLLGITRDALRDFLRAEGIAWAEDPSNEDIRYDRIKARQALAGLAPMGIDAQRLAEVAANMARAREALDWYTFLAARDLTRIDGGDVLLEPRGFRTLPDEIARRLLLHIVGWIGGGEYPPRRVAVAEALSALRHERSSQLGGCLILGQGRRIRFCREWKAVETLTVPQGALWDGRWVLRGPVVKDGELRALGAAGLKLCPDWRQTGRPYAALIASPSVWSGADLVAAPLAGLANGWTAELESGEEDFYASLLSH
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIG_PSEU2
Sequence: MSNVDRAEIAKFEALAHRWWDRESEFKPLHDINPLRVNWIDERVGLAGKKVLDVGCGGGILSEAMALRGATVTGIDMGEAPLAVAQLHQLESGVSVEYRQITAEDMAEEMPEQYDVVTCLEMLEHVPDPSSVIRACYRMVKPGGQVFFSTINRNPKAYLFAVVGAEYILNLLPRGTHDFKKFIRPSELGAWSRDAGLQVKDVIGLTYNPLTKHYKLTSDVGVNYMIQTLREA
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: SUB2_PSED2
Sequence: MKFSQSLIALAACFLPLIAAAPEEAQHAKIRSPGAQDIILDSYIVVFNKGVNDADIESEFASVSHILSKRRPAHKGVGHKYNITGFKGYQIETDTGSIGEIAASPLVAWIERDGKVQANALETRSGATWGLGRISHKATGSNSYVYDSSAGSGSTVYVVDSGIYIEHSEFEGRAKWGANYISGSPDTDENGHGTHCAGTIAGATYGVASKANLVAVKVLDGDGSGSNSGVIAGINFVGQNGKDGKSVLSMSLGGSYSAALNSAVESTISNGVTVVVAAGNDGADASNYSPASAKNAITVGAVDSTDTRADFSNYGSVLDVFAPGVDVKSAWIGSKSASNTISGTSMATPHVAGLAAYLIGLGGLSSPAAVASKIASIGIQGSVKDPKGSVNLIAYNGNGA
What is the function of this protein?
Major secreted subtilisin-like serine endopeptidase.  Preferentially cleaves substrates containing hydrophobic residues at P4, positively charged residues at P3, small or flexible residues at P2, and large, bulky residues at P1.  Mediates the degradation of collagen, the major structural protein in the mammalian host.  Degrades the nonhelical regions of collagen that function in the cross-linking of the helical components (PubMed:25944934).  May function as virulence factor involved in epidermal wing necrosis observed in white nose syndrome (WNS) in bats (By similarity).
What are the official names of this protein?
Subtilisin-like protease 2, Destructin-1, Serine protease 2, PdSP2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: HRDE2_CAEEL
Sequence: MSQNSDTFDSGLQMEVHKMAEADNSSVQQKFDAIRDYIGRKETTIILCEHDDSRKIKLTLNKQRMESSMFLTEMPDGGIQEKTKFHRNGLAVCSYNAFDEVDLPLADSYIFYGLPSNVEAFPRMLHGIEKSAHKENKIVFIDIVVSILEKIQIKVVSFELYNRKCTVPTWVAELVITYCAPIEEQQQRIEEIRRTRASVPVAISDAANGSAEMVPSNTTGSSGSPMSTAPVPAAKKEKVQYESIRQIRPNAQGRYFVPARMINMDIEMSNDEYSPDESENDENEYDYENAARYDDGYDEGHEYCQ
What is the function of this protein?
Plays a role in germline RNA interference (RNAi), and in particular is required for piwi-interacting RNA (piRNA) gene silencing.  Facilitates the binding of the argonaut protein hrde-1 to small interfering RNAs (siRNAs) targets that are required for transgenerational epigenetic inheritance and germline immortality.
What are the official names of this protein?
Protein hrde-2, Heritable RNAi deficient protein 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: AMELY_PANTR
Sequence: MGTWILFACLVGAAFAMPLPPHPGHPGYINFSYENSHSQAINVDRIALVLTPLKWYQSMIRPPYSSYGYEPMGGWLHHQIIPVVSQQHPLTHTLQSHHHIPVVPAQQPRVPQQAMMPVPGQQSMTPTQHHQPNLPLPAQQPFQPQPVQPLPHQPMQPQPPVQPMQPLLPQPPLPPMFPMRPLPPILPDLHLEAWPATDKTKRE
What is the function of this protein?
Plays a role in biomineralization.  Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development.  Thought to play a major role in the structural organization and mineralization of developing enamel (By similarity).
What are the official names of this protein?
Amelogenin, Y isoform.
What is the protein family that this protein belongs to?
Belongs to the amelogenin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: RL22_BRASB
Sequence: MSKPKRERSLPDNEAKAVARMLRVSPQKLNLVAQMIRGRKASAALADLQFSRKRIAVDVKKCLESAIANAENNHELEVDDLVVSQAFVGKGIVMKRFSPRGRGRSGRVFKPFSQLTIIVRQVEASA
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: AMPA_ECO45
Sequence: MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGKERELDERQYKQVIQKTINTLNDTGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFNVPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNVITRVIGEQQMKELGMHSYLAVGQGSQNESLMSVIEYKGNASEDARPIVLVGKGLTFDSGGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVLAGCENMPGGRAYRPGDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHITGLMANHNPLAHELIAASEQSGDRAWRLPLGDEYQEQLESNFADMANIGGRPGGAITAGCFLSRFTRKYNWAHLDIAGTAWRSGKAKGATGRPVALLAQFLLNRAGFNGEE
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURC_DESHY
Sequence: MPLHIHFVGIKGTGMSALAQVTAHIEGAHITGSDVPERFFTDAVLERAHIPVLNFSAANVEKADIVVASAAYGENHEEIARARELNIPVYSYPQFLGRLMSKKRGIAVAGTHGKTTTTAMIGLALLQSGIDPTIVVGSDVPSIGGNAYSGQGDFFLAESCEYRRHFLNYSPEYLIITNIEFDHPDYFKDLDDVVCAFSEIAQKIPPHGRIFIWHEDPQRKAIQAQSPIITFGLNEEADVYATNIQFHDEGSTMTIVAHGTVLGEFHLHVSGKHNILNALASIALCLEIGVPTEKVLESLSHFNGTKRRFEHIGQNAGALIVDDYAHHPTEIRSTLEGARLSFPDRRIRAVFQPHTFSRTEKLLQEFSQSFQAADEVVIAEIFASARETNLNTISASSLADLISQQGVNARYIHSLEEIQTYLAQTLSPGDLVLTLGAGDIYKVGQSLVC
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1634_MYCTU
Sequence: MTETASETGSWRELLSRYLGTSIVLAGGVALYATNEFLTISLLPSTIADIGGSRLYAWVTTLYLVGSVVAATTVNTMLLRVGARSSYLMGLAVFGLASLVCAAAPSMQILVAGRTLQGIAGGLLAGLGYALINSTLPKSLWTRGSALVSAMWGVATLIGPATGGLFAQLGLWRWAFGVMTLLTALMAMLVPVALGAGGVGPGGETPVGSTHKVPVWSLLLMGAAALAISVAALPNYLVQTAGLLAAAALLVAVFVVVDWRIHAAVLPPSVFGSGPLKWIYLTMSVQMIAAMVDTYVPLFGQRLGHLTPVAAGFLGAALAVGWTVGEVASASLNSARVIGHVVAAAPLVMASGLALGAVTQRADAPVGIIALWALALLIIGTGIGIAWPHLTVRAMDSVADPAESSAAAAAINVVQLISGAFGAGLAGVVVNTAKGGEVAAARGLYMAFTVLAAAGVIASYQATHRDRRLPR
What is the function of this protein?
Could be involved in fluoroquinolones efflux.
What are the official names of this protein?
Probable multidrug-efflux transporter Rv1634.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL20_STRS7
Sequence: MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYYYAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVNDAAAFTALADAAKAKLGK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: LEUC_METS5
Sequence: MTGTLTEKILSRASGKTVSPGDVIEAKTDIVAFHDLTGYHVIEVMEKANMMKIFDKTKIVVAFDHLAPPPDVRSAEIQGNIRKFVKEMRLPNFHDINVGILHELLIEQYALPGQVIVAADSHTTTSGAVGAFAQGMGASDVAAAVITGKTWLVVPQPFKVTLKGNPGKWINGKDVALELLGKFKADYFNGMSIEVHVENPKAFPMDYRATVSNMGIEMNADALMFVPDVETKDYIKTMRGKEVELVTPDPGAKYLDEHTIELDKLEPLVAAPYSVDNVKTAREESKVPVDQVYIGSCTNGRLSDFRIASEILKGKKVKTRCIAIPSSYTMFKQAMEMGYIEDLVNAGCVVTYGTCGPCLGGHFGVAGPGEVIVSTSSRNFRGRMGSNEAKVYLSGPSVAAASAATGYITDPRDVQ
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
Protein: VP91_NPVCF
Sequence: MSGVVLLVLAIILITIFSLIYYTIFFEFDETTFSKRLRVLTEYAKRTNADKPTPDVLGHVSDVYDHTYIVSWFRTNDLSTYHETVHDDTVEVFDFLEQQFSGAQATVTQRVAPVAAELDAFVVTNDAGDVKLRCPQNFSFDYGQLKCVPEDPCSGRPPGRYPMNELLLDTLVHNQHSDKNYSAGAHLYHPTLYLRCLANGSHAVRECPDNYTFDAEAGECRVNELCEGRPDGFVLPYFPEALLVNEFVECRNGEHVVAQCADGQVFDRALMTCVHAHPCAFNGAGHTYITSDIGDTQFFKCLNNHEAQLVTCINRAHGADGQYACSGDARCADLPKGTGQLVHIHTDDTFEYASGQMICDNYEVVSEINCDTGDVLGDKLFINKFKLNVQFPLEVLEFGACAPATLNNVSVLNDTFPIENAPNDYGVNMQTSVVGRTSMVAKLMAGDDPDTAFGENVLLARDVNTVGLNPFTAEPIDCFGAQLYDVMDAHRANVCTESGNDLLKTVEFGDGAFLSVFRDDLTGSDADYKQFCAISYESPLKIVKSDHFQRRILTNILQSDICADLYTTIYQKYTTLARKYTTSPVQYNYTFVKRPENMVVYAKNTRFKNATISEPAFDLFAAQTTDKENGFARSLFDPFADGVWRSEPGGDGDHWAPEVPPTQPEPELEPESETELDSDLELEPEFSPLILNKKDLFYSCFYELPSFKLSSCHAENDVIVDALQQLRASVKVDTECELAKDLHFVLNAYAYTGNNIGCRSVFDGDDVAVVKEPVPSYVFTNLQTQSNDGVRYNKHVHVKDGRYMACPEHLYDDEAFACNAEPDKLYYLENMQQ
What is the function of this protein?
Probable capsid-associated protein.
What are the official names of this protein?
Capsid-associated protein Vp91.
What are the subcellular locations of this protein?
Virion. Note=In virions, associates with the capsid and maybe also with the envelope surrounding the capsid.
Protein: PURL_PYRHO
Sequence: MFPQEEKLIRERLGREPNDVERAMLEVMWSEHVSYKSSRKWLKLLPTKNEHVVLGPGEDAGIIKFDDKTWIVIGIESHNHPSAVEPYGGAATGVGGIVRDILCMGARPIALLDPIRFGPLEKEKNRYLFEYVVKGISDYGNRIGVPTVGGETEFDESLDNYTLVNVACVGIMKPEHLVHSYVTEPGLKLIIVGNRTGRDGIHGVTFASEELSENAEEEDRSAVQIPDPFTEKLLIEATLEAVYTGKVRALKDLGGGGLTCAASEMVGKRGFGAIIYADKVLLREPGMTPLEVMISESQERMLFAVRPEDVEELARIFEKYELEWSVVGEVIEEPKFIVYWKGSKVAELPIDLLTEVPTIEWPMKEYKIEEEVGIPRISLQEAFEKVWRSPNIVAKRWIWEQYDHEVQGRTVVKPGFDSAVLKINEEYGIAITADGNPNHCYLNPYHGAMGLVAEVVRNLVSVGAKPLALVDNLNFASPERPEVYWSFAETVKGLADAAKAFNLAYVSGNVSFYNEIVDKPIKPTPVVAGVGKVKLSKIPKGPNKGDVVTLVGETKRELGGSELYRVLGIRKGIAPRVNLEVERKNAESILRLINASLVSFVHDLSRGGLLVALAEVAALFNVGMEVTIKTDMNPVEFAFSESHGRYLVVLPERKLEEAREITDLKVIGRIIGSNSFSVKINDEVLLWNLDKLKDVYWNTLYRLMD
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_RICPR
Sequence: MATKKAGGSSRNGRDSAGRRLGVKKSDGQYVIPGNIIVRQRGTKIHPGINVGLGKDHTIFSLIEGRVEFLTKQSHKIVNVKEIANV
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.