PharMolix/UniProtQA huggingface dataset:
Protein: NDK_CAMJR
Sequence: MEKTLSIIKPDAVKKGVIGKILDRFESNGLRIAAMKKVQLSKEQAENFYAVHKERPFFKDLVEFMISGPVVVSVLEGEGAVLKNRDLMGATNPKEAKAGTIRADFAESIDANAVHGSDSLENAKIEIDFFFKPNEIC
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TFE_METMP
Sequence: MLENPLIQQVLFEIMDEDVVGFDVLSVLINTNEVTDDEISRQLDVKLNNIRRILYKLYEARLVDYNREKDEETNWYTYTWKPSLEKVPALVAKKMKNVLNGLKEQLNVEENNMFFFCSDCEIKFTFEDAMDSGFRCPQCGEMMYEYDNKKDISLLKEQIKYLEDEFNKNPLFSTY
What is the function of this protein?
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase.  Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment.  Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal.  It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes.  Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
What are the official names of this protein?
Transcription factor E, TFE, TFIIE subunit alpha homolog, Transcription initiation factor TFIIE.
What is the protein family that this protein belongs to?
Belongs to the TFE family.
Protein: RLMI_SHESM
Sequence: MAVRIKLKPGREKSLERRHPWVFSNGIHNVKGKLEAGDTVDVVAHDGHWLGRGAWSPESQIQVRIWTFDREEEIDREFFKRRILRAQAGRDDLIREQGLTGYRLIAAESDGLPGITIDKYANVLVCQLLSMGADVWRDTIVDVLAELYPDCAIYERSDVDSRKKEGLASTMGLLHGTLPEMPVIIEENGIKIAVDVTKGHKTGFYLDQRDNRAMAARFVKGKSVLNCFCYTGTFGLYAAKAGAASIENVDVSALALDTARLNMRVNGLNDDNVHYNEADVFKLLRQYRDEGKTFDVIVLDPPKFADNKSQLNGACRGYKDINMIALQLLNPGGVLLTFSCSGLMPADLFQKIVADAALDAKREIQFIERLSQASDHPIGSAFPEGFYLKGLVARVW
What is the function of this protein?
Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase I, 23S rRNA m5C1962 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RlmI.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBB4_ORYSJ
Sequence: MREILHIQGGQCGNQIGAKFWEVVCDEHGIDPTGRYTGNSDLQLERVNVYYNEASCGRFVPRAVLMDLEPGTMDSVRTGPYGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELIDSVLDVVRKEAENCDCLQGFQVCHSLGGGTGSGMGTLLISKIREEYPDRMMLTFSVFPSPKVSDTVVEPYNATLSVHQLVENADECMVLDNEALYDICFRTLKLTTPSFGDLNHLISATMSGVTCCLRFPGQLNSDLRKLAVNLIPFPRLHFFMVGFAPLTSRGSQQYRALTVPELTQQMWDAKNMMCAADPRHGRYLTASAMFRGKMSTKEVDEQMINVQNKNSSYFVEWIPNNVKSSVCDIPPRGLSMASTFIGNSTSIQEMFRRVSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEEGEYEDEEQQEADDM
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta-4 chain, Beta-4-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: KATG_YERPA
Sequence: MLKKILPVLITLAIVHNTPTAWAAEAPKTDSFYLPKSLDLSPLRLHNIESNPYGKDFNYAQQFKTLDLEAVKKDIKTVLTTSQDWWPADYGNYGPFFIRMAWHGAGTYRIYDGRGGADGGQQRFEPLNSWPDNANLDKARRLLWPIKKKYGAKISWGDLMVLTGNVALESMGFKTLGFAGGREDDWQSDLVYWGAGNKMLSDNRDKNGKLPKPLAATQMGLIYVNPEGPNGKPDPVAAAKDIREAFARMAMNDEETVALIAGGHTFGKAHGAASPEKCLGAAPGEAGLEQQGLGWANKCGSGNGKDTITSGLEGAWTTDPTHFTMQYLSNLYKHEWVLTKSPAGAWQWKPKNAANVVPDATDPTKFHPLMMFTTDIALKVDPEYKKITTRFLENPEEFKMAFARAWFKLTHRDMGPAARYLGDEVPKETFIWQDPLPAANYKMIDSADISELKDKILKTGLSDTKLIKTAWASASTFRGTDFRGGDNGARIRLAPQKDWPVNDPAELHSVLAALMEVQNNFNKDRSDGKKVSLSDLIVLGGNAAIEDAAKKAGYSISIPFTPGRTDASQEETDVSSFAVLEPTADGFRNYYDAKRNTLSPIASLIDRANKLELTVPEMTVLIGGLRVLDVNSGGSKAGVLTNTPGQLNNNFFVNLLDMSTKWTKSPKAEGYFDGYDRKTGKLKWTASSVDLVFGSNPELRAVAEVYASDDAKEKFVHDFTKVWEKVMNLDRFDIKNN
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: RS18_ALIF1
Sequence: MARFFRRRKFCRFTAEGVQEIDYKDVATLKNYITEAGKIVPSRITGTRAKYQRQLARAIKRSRYLALLPYTDKHL
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: YIDD2_BACLD
Sequence: MKTVFLLLIRFYQKWISPALPPTCRFYPTCSNYGLEAIEKHGAFKGGWLTIKRILKCHPFHPGGIDPVPEKKQKD
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor 2.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RNL1_NPVAC
Sequence: MLHVSRLLANGGVKNLCDKFKVKIKNYTEHDLMVLNYESFERDRDHPVVVECRGLILNSRTYAVVSRSFDRFFNFQELLQNIGGEDAHHKLFQSKENFKFYEKIDGSLIKIYKYNGEWHASTRGSAFAENLCVSDVTFKRLVLQALQLDEAHNQFQALCNEYLDCASTHMFELTSKHNRIVTVYDEQPTLWYLASRNNETGDYFYCSNLPFCKYPKCYEFTSVQECVEHAAQLKNLEEGFVVYDKNNAPLCKIKSDVYLNMHKNQSRAENPTKLAQLVINGEHDDFLALFPHLKSVIKPYVDARNTFTNESTINIMVSGLTLNQQRFNELVQTLPWKCLAYRCRKAQTIDVESEFLKLTEPEKIKMIKNIIKFVSTKQALNNKLAPTIKLPSSKQLLVLIGISGSGKSTYAKSLKGYTEINRDDVRVKLFLNGDYTKLNAFYNQSRKCRQTKEEQITKMCIEQFLKAAKCGANVVVSDTNLNTQSVDMWQKMAATHNYHFLTRLMDVSLETALERNYKRSDKFPLNPETIKKQYKKFLKVNNFEYYVPVGDKFPRAVLCDLDGTVALPTNRSFYDFDNRVAQDEARLDVITCVKYLANCHDAIIVFMSGRSVICEQPTRNWIEKYFDIKSYKLFMRPSDDTCKDYLLKLKLFNNYIRGKYNVIAVFDDRPCVVRMWQDLKIPTVFNVCRDYLEF
What is the function of this protein?
Trifunctional enzyme that possesses a bifunctional polynucleotide kinase/phosphatase activity and an ATP-dependent RNA ligase activity.  May therefore play a role to evade an RNA damage-based host response.
What are the official names of this protein?
Putative bifunctional polynucleotide kinase/RNA ligase.
Protein: TRPC_STUS1
Sequence: MSVPTVLEKIIARKLEEVAERSRRIGLAELEQQAAIADPVRGFAAALEQRVNAKEPAVIAEVKKASPSKGVIRDPFLPAEIAAGYEAGGAACLSVLTDIDFFQGADAYLQQARAACSLPVIRKDFMIDPYQVVEARALGADCILLIVAALDDARMHELAAVAKAHGLDVLVEVHDGDELERALRLETPLVGINNRNLHTFEVSLETTLDLLPRVPKDRLVITESGILNRADVELMEINQVYAFLVGEAFMRAEQPGVELQRLFFPDRARSRGVVADPE
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: CATD_HUMAN
Sequence: MQPSSLLPLALCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEVLKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITFIAAKFDGILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDPDAQPGGELMLGGTDSKYYKGSLSYLNVTRKAYWQVHLDQVEVASGLTLCKEGCEAIVDTGTSLMVGPVDEVRELQKAIGAVPLIQGEYMIPCEKVSTLPAITLKLGGKGYKLSPEDYTLKVSQAGKTLCLSGFMGMDIPPPSGPLWILGDVFIGRYYTVFDRDNNRVGFAEAARL
What is the function of this protein?
Acid protease active in intracellular protein breakdown.  Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation (PubMed:27333034).  Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.
What are the official names of this protein?
Cathepsin D.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
Protein: RL31_SHESM
Sequence: MKPGIHPEYAVITANCTCGNVIKVNSTAGKDLHLDVCGACHPFYTGTQKVVDTGGRIDKFNKRFGMLGKK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: NUOK_STRMK
Sequence: MITLGHMLALGAVLFAISLAGIFLNRKNVIVLLMSIELMLLSVNINFVGFSRQLGDPSGQLFVFFILTVAAAEAAIGLAILVTLFRTRRTINVGEVDSLKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYM_TREPA
Sequence: MTRKLITAALPYVNNVPHLGNLIQGLSADVFARFCRMRGYHTCFVCGTDEYGTASETRAAEQGLSPAQLCAHYHALHRDIYQWFDLSFDYFGRTTSDAHTELTQALFRHLDARGFISEHESAQAYCLHCARFLADRYLRGTCPHCRNAEARADQCEHCGVLLEPETLLNARCVSCGTAPEFRPTRHLYLNLPALEKAYRSWFCTTNHLWTKNAVRMTEGWLRTGLQERAITRDLRWGVPVPKAGFEQKVFYVWFDAPVGYISITKCGTEAASSQEGGGTDDGVKEKWQSWWLDQQDVELVQFVGKDNIPFHTLFFPCMLIGSGQRWTMLTRLSATEYLNYEGGKFSKSLGVGVFGSDAKESGIPSDLWRFYLLYHRPEKSDAHFTWHEFQERVNSELIGNLCNLVNRTLTFVARTYGGVVPAQDGARSTRAQVMEETLALREAVRNTAKRMTDLMEQVQLREAFREVFALSARANKALQDGAPWKTRAQDRERADALMRELCYVIRDVLILAHPFLPWYTQQAARFLGVQLSSCAPEGGGAVCAAKKDADTAQPDTVQPTLRWSDVGERKGLTQVHPPVILFRPLETETIAAYRARYAGTARDGAGVSVPRTAQMPTGMNKKETDAQQKKEEREMPPPSDTARLSAFFSERVVLKVARVLQVERHPNADMLFVETLDDGSGVERVIVSGLVPYMAADALRGAHVLIVDNLQPRSLRGVRSCGMLLAAEYVDAQGTKAIELVQAPWALPGERATLASAPPVITPHGSAVIDADAFFSVPIRVVNYAVEVAGEPLMVGGRPLVMQRVKEGTVG
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SO1BT_HUMAN
Sequence: MDQHQHLNKTAESASSEKKKTRRCNGFKMFLAALSFSYIAKALGGIIMKISITQIERRFDISSSLAGLIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTSLPHFFMGYYRYSKETNIDPSENSTSNLPNCLINQMLSLNRTPSEIIERGCVKESGSHMWIYVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMGMTGLVFAFMLGSLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPFFFLPLNPNKPQKERKVSLFLHVLKTNDKRNQIANLTNRRKYITKNVTGFFQSLKSILTNPLYVIFVIFTLLHMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVLALPAVAIGMFSGGYIIKKFKLSLVGLAKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTYDGNSPVRSHVDVPLSYCNSECNCDESQWEPVCGNNGITYLSPCLAGCKSSSGNKEPIVFYNCSCVEVIGLQNKNYSAHLGECPRDDACTRKSYVYFVIQVLDAFLCAVGLTSYSVLVIRIVQPELKALAIGFHSMIMRSLGGILVPIYFGALIDTTCMKWSTNSCGARGACRIYNSTYLGRAFFGLKVALIFPVLVLLTVFIFVVRKKSHGKDTKVLENERQVMDEANLEFLNDSEHFVPSAEEQ
What is the function of this protein?
Mediates the Na(+)-independent uptake of organic anions (PubMed:29248594).  Transports the conjugated steroids 17-beta-glucuronosyl estradiol (17beta-estradiol 17-O-(beta-D-glucuronate) or E2G) and dehydroepiandrosterone 3-sulfate (DHEAS) at the smooth endoplasmic reticulum membrane (SER), granting access to metabolizing enzymes (PubMed:29248594, PubMed:31127008, PubMed:32818652).  Contributes to the metabolism of bile acids such as taurocholate (cholyltaurine) and lithocholate, by functioning as a doorway between SER and cytosol, thereby decreasing their circulating levels and protecting the organism from their detergent properties (PubMed:31509437).  Regulates access or exit of drugs to the SER lumen (PubMed:31127008).
What are the official names of this protein?
SLCO1B3-SLCO1B7 readthrough transcript protein, Liver specific transporter-3 transmembrane 12, LST-3TM12, Organic anion transporting polypeptide 1B3-1B7, OATP1B3-1B7, Solute carrier organic anion transporter family member 1B3-1B7, SLCO1B3-SLCO1B7.
What is the protein family that this protein belongs to?
Belongs to the organo anion transporter (TC 2.A.60) family.
Protein: CAPP_SHISS
Sequence: MNEQYSALRSNVSMLGKVLGETIKDALGEHILERVETIRKLSKSSRAGNDANRQELLTTLQNLSNDELLPVARAFSQFLNLANTAEQYHSISPKGEAASNPEVIARTLRKLKNQPELSEDTIKKAVESLSLELVLTAHPTEITRRTLIHKMVEVNACLKQLDNKDIADYEHNQLMRRLRQLIAQSWHTDEIRKLRPSPVDEAKWGFAVVENSLWQGVPNYLRELNEQLEENLGYKLPVEFVPVRFTSWMGGDRDGNPNVTADITRHVLLLSRWKATDLFLKDIQVLVSELSMVEATPELLALVGEEGAAEPYRYLMKNLRSRLMATQAWLEARLKGEELPKPEGLLTQNEELWEPLYACYQSLQACGMGIIANGDLLDTLRRVKCFGVPLVRIDIRQESTRHTEALGELTRYLGIGDYESWSEADKQAFLIRELNSKRPLLPRNWQPSAETREVLDTCQVIAEAPQGSIAAYVISMAKTPSDVLAVHLLLKEAGIGFAMPVAPLFETLDDLNNANDVMTQLLNIDWYRGLIQGKQMVMIGYSDSAKDAGVMAASWAQYQAQDALIKTCEKAGIELTLFHGRGGSIGRGGAPAHAALLSQPPGSLKGGLRVTEQGEMIRFKYGLPEITVSSLSLYTGAILEANLLPPPEPKESWRRIMDELSVISCDLYRGYVRENKDFVPYFRSATPEQELGKLPLGSRPAKRRPTGGVESLRAIPWIFAWTQNRLMLPAWLGAGTALQKVVEDGKQSELEAMCRDWPFFSTRLGMLEMVFAKADLWLAEYYDQRLVDKALWPLGKELRNLQEEDIKVVLAIANDSHLMADLPWIAESIQLRNIYTDPLNVLQAELLHRSRQAEKEGQEPDPRVEQALMVTIAGIAAGMRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: APRR3_ARATH
Sequence: MCFNNIETGDEVETERQVFGSSEEDEFRVEDTARNTNNVQISQQQQQPLAHVVKWERYLPVRSLKVLLVENDDSTRHIVTALLKNCSYEVTAVPDVLEAWRILEDEKSCIDLVLTEVDMPVHSGTGLLSKIMSHKTLKNIPVIMMSSHDSMVLVFKCLSNGAVDFLVKPIRKNELKNLWQHVWRRCHSSSGSGSESGIHDKKSVKPESTQGSENDASISDEHRNESGSSGGLSNQDGGSDNGSGTQSSWTKRASDTKSTSPSNQFPDAPNKKGTYENGCAHVNRLKEAEDQKEQIGTGSQTGMSMSKKAEEPGDLEKNAKYSVQALERNNDDTLNRSSGNSQVESKAPSSNREDLQSLEQTLKKTREDRDYKVGDRSVLRHSNLSAFSKYNNGATSAKKAPEENVESCSPHDSPIAKLLGSSSSSDNPLKQQSSGSDRWAQREAALMKFRLKRKERCFEKKVRYHSRKKLAEQRPHVKGQFIRKRDDHKSGSEDN
What is the function of this protein?
Controls photoperiodic flowering response.  Component of the circadian clock.  Controls the degradation of APRR1/TOC1 by the SCF(ZTL) complex.  Expression of several members of the ARR-like family is controlled by circadian rhythm.  The particular coordinated sequential expression of APRR9, APRR7, APRR5, APRR3 and APPR1 result to circadian waves that may be at the basis of the endogenous circadian clock.
What are the official names of this protein?
Two-component response regulator-like APRR3, Pseudo-response regulator 3.
What is the protein family that this protein belongs to?
Belongs to the ARR-like family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ERG27_CANAL
Sequence: MSLLKDSTVAVITGTSSNLGFNIAVRLLEGLPDNKEITLVVTSRTLPKVKEVISDIKKYIVAKIPTKVNKVEFDYLLVDFTDMVSILSAYYELNKRYKHIDYLFINAAQGVYGGIDWTGAVLEVLQSPIEAVTNPTYKLQKVGVESGDKLGLVFQANVFGPYYFIHRIKHLLENGGKIVWVSSLMSSPKYLSFNDLQLLRSPASYEGSKRLVDLMHFGTYNKLEREHGIKQYLVHPGIFTSFSFFQYLNVFTYYGMLFLFYLARFLGSPYHNISGYIAANAPVAAALGQTKQNCKTASACTRSGKEYLLEEEIDSTGSDDVVSYLDTLTKEWDEKLKDQIVNTRQP
What is the function of this protein?
Facilitates the association of ERG7 with lipid particles preventing its digestion in the endoplasmic reticulum and the lipid particles.
What are the official names of this protein?
3-keto-steroid reductase ERG27.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. ERG27 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Lipid droplet.
Protein: ICAD_STAEP
Sequence: MVKPRQRQYPTVTSYLNIVRESLFITISGVFWMYCIVVMIVYIGTLINSQMESVITIRIALNVENTEIYKLFGWMSLFVLIIFIFFTFSLAFQKYKKGRDI
What is the function of this protein?
Necessary for the synthesis of poly-beta-1,6-N-acetyl-D-glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide.  Is required for full IcaA N-acetylglucosaminyltransferase activity (By similarity).
What are the official names of this protein?
Poly-beta-1,6-N-acetyl-D-glucosamine synthesis protein IcaD, PGA synthesis protein IcaD, Poly-beta-1,6-GlcNAc synthesis protein IcaD, Biofilm polysaccharide intercellular adhesin synthesis protein IcaD, Biofilm PIA synthesis protein IcaD, Intercellular adhesion protein D.
What is the protein family that this protein belongs to?
Belongs to the IcaD family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: QUEC_PSEPU
Sequence: MTEKRAVILLSGGLDSATVVAMAKAEGYSCYTMSFDYGQRHRAELNAAARVARDLGVVEHKVIGLNLDGIGGSALTDSSIDVPEAPGEGIPVTYVPARNTVFLSLALGWAEVLEARDIFIGVNAVDYSGYPDCRPEFVEAFERMANLATKAGVEGQGFRIQAPLQNMSKAQIVQAGMARGVDYSLTVSCYQADDDGRACGKCDSCRLRADGFKAAGIEDPTRYF
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: GSA_YERPB
Sequence: MSKSENLYAQAQQLIPGGVNSPVRAFTGVGGIPLFIERADGAYLFDVDGKAYIDYVGSWGPMILGHNHPAIRQAVIEAVERGLSFGAPTEMEVKMAQLVTDLVPTMDMVRMVNSGTEATMSAIRLARGYTGRDKIIKFEGCYHGHADCLLVKAGSGALTLGQPNSPGVPADFAKHTLTCTYNDLASVRQAFEQYPQEVACIIVEPVAGNMNCIPPLPEFLPGLRALCDEFGALLIIDEVMTGFRVALAGAQDYYHVIPDLTCLGKIIGGGMPVGAFGGRREVMNALAPTGPVYQAGTLSGNPIAMAAGFACLTEISQVGVYETLTELTDSLATGLRHAAKEENIPLVVNHVGGMFGLFFTNADTVTCYQDVMNCDVERFKRFFHLMLEEGVYLAPSAFEAGFMSLAHSNEDIQKTVNAARRCFAKL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH1_CALS4
Sequence: MIDKEKIKKAVREILEAIGEDPDREGLLETPDRVARMYEEIFSGLHTDVKDVIKIFQEDEHQEIILVKDIPLYSMCEHHLLPFIGVAHVAYLPRKGRILGLSKVARIVDVLSKRPQLQERLTSEIADTIMEAVNPLGVAVVIEAEHLCMTMRGVKKPGSKTVTSALRGIFRTDQKARAEVMALINSKR
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: PO3F3_RAT
Sequence: MATAASNPYLPGNSLLAAGSIVHSDAAGAGGGGGGGGGGGGGAGGGGGGMQPGSAAVTSGAYRGDPSSVKMVQSDFMQGAMAASNGGHMLSHAHQWVTALPHAAAAAAAAAAAAVEASSPWSGSAVGMAGSPQQPPRPPPPPPQGPDVKGGVGREDLHAGTALHHRGPPHLGPPPPPPHQGHPGGWGAAAAAAAAAAAAAAAAHLPSMAGGQQPPPQSLLYSQPGGFTVNGMLSAPPGPGGGGGGAGGGAQSLVHPGLVRGDTPELAEHHHHHHHHAHPHPPHPHHAQGPPHHGGGGAGPGLNSHDPHSDEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITNLADSLQLEKEVVRVWFCNRRQKEKRMTPPGIQQQTPDDVYSQVGTVSADTPPPHHGLQTSVQ
What is the function of this protein?
Transcription factor that acts synergistically with SOX11 and SOX4.  Plays a role in neuronal development.  Is implicated in an enhancer activity at the embryonic met-mesencephalic junction; the enhancer element contains the octamer motif (5'-ATTTGCAT-3') (By similarity).
What are the official names of this protein?
POU domain, class 3, transcription factor 3, Brain-specific homeobox/POU domain protein 1, Brain-1, Brn-1.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-3 subfamily.
Protein: Y660_PELUB
Sequence: MLDIKNPIEARKVIRKNEYRNQTAGTANKYVQGNLCILPSKYAMDFASFCQKNPKPCPLIGFGTKGDPSLKDLGDIDIRTDVPQYRIWEKGKIIDEPYDIKKYWNEDLTTFVLGCSMSFELPLIEAGIPIQHIENDTIVPMYRTSIDCEPAGQFSGKLVVSMRPLNSKDAIRSIQISSRFPAVHGAPIHLGDPSEIGIKDIMNPEYGDPPKAFKNNEIPVFWACGVTPQSVLQDSKPDFCITHAPGKMLITDKLNNDLAAL
What are the official names of this protein?
Putative hydro-lyase SAR11_0660.
What is the protein family that this protein belongs to?
Belongs to the D-glutamate cyclase family.
Protein: ACCD_EPIVI
Sequence: MERWRFSLMVFNNKLKHEYGIKKSLDSVSSIENTIENKDSNSKPNIKGRAQNIRSCGGRDNYSYNNIIYLFGVEYNRNLIPNDTFLFRDNKGDSFYISFNIENHIFEIDINFSCLSELEIERYFYSYHGFDYFNFNNGSAIEDYLYNHYMYDTPSNNHITSCIESYLQSQICVNPSIISDSSDSYIFGCFDKRRTHNESRRSGIRNRAQSSYLTIRESFNNLDSTKKYKHLWVQCENCYGLNYKKFLKSKINLCEQCGYHFKMSSSERIEVLVDPDTWYPMDEDMSSLDPIEFHSEEEPYKDRIYSYQKRTGLTEAVQTGLGQLNGIPIAIGVMDFQFMGGSMGSVVGEKITRLIEYATNKILPLIIVCASGGARMQEGSLSLMQMAKISSALFDYQSNKKLLYVSILTSPTTGGVTASFGMLGDIIIAEPNSYIAFAGKRVIEQTLHKIVPEGSQAAEYLFQKGLFDLIIPRNLLKSVLGELFKLHAFFPLN
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Plastid stroma.
Protein: NU6M_BRALA
Sequence: MQMMLMFLLLLAAIMVIRATSPYYGALATAWLALLAALLLLDADIIFPAIILMLIYLGGMLVVFIYSTAYAADLMPLPINLTMSALMASFGVMLITMISSPSIETLCETKPWLVYDMQPSYMLFDIYQRGSSMFIVAVMILTALLFSILEVVSHRQTTMKWFIHSTY
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: NDK_STRZP
Sequence: MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEELIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTIRGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADK_BORBU
Sequence: MKNKVLLCINTLKSGASILGNDVKVYLETKYFVEVVLIDVGRPLFSFPKENFLFLITLGGDGTVLLAVNLLLENENIDIPIISINMGNVGFLADIKIEDFKKVIDRFFNNSLVINKKFLLHVTVSQHGKDLISKYALNDIIIRSSVLNKMIYVDLMVNSESFLSYKSDGIIVSTPTGSTGYSFSAGGPILEADLEGFXLTPISPHSVYNRSFVFSKLSKLSISFSKEYFIAAASIFLDGINFGSFGVDVVFEFKISSQSLNFVSFCTDTFVKRLKNKLL
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.