PharMolix/UniProtQA huggingface dataset:
Protein: SP0A_BACTU
Sequence: MEKIKVCLVDDNKELVSMLESYVAAQDDMEVIGTAYNGQECLNLLTDKQPDVLVLDIIMPHLDGLAVLEKMRHIERLKQPSVIMLTAFGQEDVTKKAVDLGASYFILKPFDMENLTSHIRQVSGKANAMIKRPLPSFRSATTVDGKPKNLDASITSIIHEIGVPAHIKGYMYLREAISMVYNDIELLGSITKVLYPDIAKKYNTTASRVERAIRHAIEVAWSRGNIDSISSLFGYTVSMSKAKPTNSEFIAMVADKLRLEHKAS
What is the function of this protein?
May play the central regulatory role in sporulation.  It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress.  Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.  Repressor of abrB, activator of the spoIIa operon.  Binds the DNA sequence 5'-TGNCGAA-3' (0A box) (By similarity).
What are the official names of this protein?
Stage 0 sporulation protein A.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUC_HAEIN
Sequence: MLEILYQDGFLVAVNKPAGMLVHRSWLDPHETQFVMQTLRDQIGQHVFPIHRLDRPTSGVLLFALSSEIANLMCEQFEQKYVQKSYLAVVRGYLQGKERIDYPLKIQLDKIADKFSQEDKEPQEAITDYEGLKIVEMPYPAGRYQTARYSLVKLIPHTGRKHXLRXHMKHVFHPIXGDTQYGDLHQNRALMSHLGCSRLFLHSDSLSFIHPITKEQITITAGLDEQWQQLMNQFGWENV
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-65 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase C, tRNA pseudouridine(65) synthase, tRNA pseudouridylate synthase C, tRNA-uridine isomerase C.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RluA family.
Protein: NHR85_CAEEL
Sequence: MDLSTSGSLPCHLPLSLLTNLQTPPIDTSFSSPPATSSSSLLSPSPSSAFRPVVPKSLMNPQPAMDTFYMSAIQSLVVSTTNDDQYSEHGALEGSKSLAKDENASTSAGTILCQVCSDKASGFHYGVFACEGCKGFFRRSIQQKITYRACTRAEDCLILRNNRNRCQCCRLKKCLAVGMSRDAVRFGRVPKREKARMFEEMQKTNVQSQRDQIAIQYENLTEVMHKINQAFGTLQATLEKCTGPIYTDRCPITSNFIVIPLKAAIDFANSIPAFLSITQTQRVHLLQNSVFDVMLLASASASTSQHFPPGGLTYDQSSANPIIPQAIQSISARIRQLPPQTVPILTAIAVCQADLLPESQQPMLLAERLWCVLGKLGGIQSLATAPSLLADVRTLRQWHSDRLRQMSQISQHFSQNLLIAPVAAAAPVLLPPAFLSPPASATSTSSSSVKSEFIERHPSIASLLERPRRISSSGAQEPLNLSLPHVRHQVKRDVDSDEQLEEMKVSPVPTTLSE
What is the function of this protein?
Orphan nuclear receptor.
What are the official names of this protein?
Nuclear hormone receptor family member nhr-85.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HSCA_PSEA8
Sequence: MALLQIAEPGQSPKPHERRLAVGIDLGTTNSLVAAVRSGVAEPLPDAQGRLILPSAVRYHAERAEVGESARAAAAEDPFNTVISVKRLMGRGLEDVKQLGEQLPYRFRQGESHMPFIETVQGLKSPVEVSADILRELRQRAETTLGGELVGAVITVPAYFDDAQRQATKDAARLAGLNVLRLLNEPTAAAVAYGLDKGAEGLVAIYDLGGGTFDISILRLTRGVFEVLATGGDTALGGDDFDHAIAGWVIEEAGLSADLDPGSQRQLLQIACAAKERLTDEASVRVAYGDWSGELSRATLDELIEPFVARSLKSCRRAVRDSGVDLEEIRSVVMVGGSTRVPRVRTAVGELFGCEPLTDIDPDQVVAIGAAIQADALAGNKRGEELLLLDVIPLSLGLETMGGLMEKVIPRNTTIPVARAQEFTTYKDGQTAMMIHVLQGERELVKDCRSLARFELRGIPPMVAGAAKIRVTFQVDADGLLGVSARELSSGVEASIQVKPSYGLTDGEIARMLKDSFDYAGDDKAARALREQQVEAQRLLEAVQSALDVDGERLLDEEERLAIAAQMDTLRELAGGSDTAAIENQIKRLSQVTDAFAARRMDATVKAALSGRRLNEIEE
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: HOT_ANOGA
Sequence: MWNRGRIVSLMRTVSSGSCSCPAHSRPVAISQQTSCSAEKDTAFEMSSSTIRYGPGVTRELGHDLQNLGAKSVCVVSDRNVLQLPSVKVGLDAIVRAGIEPVLFDAVRVEPTNESLQTAIDFARSHRFDAFVAIGGGSAIDTCKVANLYSADREAEFLDYVNVPIGRAKEVTVPLKPLIAVPTTAGTGSETTGVAIFDHKPLHAKTGISSKALRPILGLVDPLHTLSQPEKVAAYCGFDVFCHALESFTAIPYTERGPAPANPKLRPPYQGSNPISDVWARFALQTISRHFRRAVYAPDDLEARSQMHLASTMAGVGFGNAGVHLCHGLSYPIAGLVKQFIPDGYTGAHPIIPHGLSVVMTAPSVFRFTGASCPDRHLEAAGILGADVAKSHRNDAGAILADTVRRYMHDLKIENGLSALGFNYSDIPALVKGTLPQERITKLAPRAQSEEDLAGLFEQSLTVY
What is the function of this protein?
Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG).  L-3-hydroxybutyrate (L-3-OHB) is also a substrate for HOT when using 2-KG as hydrogen acceptor, resulting in the formation of D-2-HG (By similarity).
What are the official names of this protein?
Probable hydroxyacid-oxoacid transhydrogenase, mitochondrial, HOT.
What is the protein family that this protein belongs to?
Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PDXH_PSEP1
Sequence: MTQSLADMRRDYTRDGLAEAQAPGEPFALFHQWFADAVKTEQVPVEANAMTLATVDGEGRPHCRVLLLKGLDEQGFTFFTNYDSAKGQQLQANPFAAMTFFWPALERQVRIEGRVQKVTAQESDAYYQVRPLGSRLGAWASPQSRVIAGREELEGLVKATEARFSDTQPHCPEHWGGYRLLPERIEFWQGRASRLHDRLNYRLVDGQWLRERLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: MURD_BACC1
Sequence: MKTVTEFQNKNILVLGIAKSGYAAATLLQKLGANVIVNDGKPLAENVLAAELQAKGMDVVCGGHPLELLERNISLVVKNPGIPYSNPILVAAKEKQIPIVTEVELAYRISEAPFVGITGSNGKTTTTMLTFEMLKEGQKHPVIAGNIGTVACEVAQDAKENEVVVTELSSFQLMGVELFQPKIAAFLNLFEAHLDYHGTKKEYGLAKANIFKNXTENDYSVINADDADVMALSAYSKGQKVLFSTTKEIEDGACIKDNALYFKGEKVVEVGDIVLPGQHNLENILAAMSIAKLLGVSNEAITAVLKRFTGVKHRLEYVTTINNRKFYNDSKATNMLATEKALSAFTQPTVLLAGGLDRGNEFDDLIPYFKNVKAIVTFGQTAPKLVRAAEKAGLDTIESVDTLDEAVVKAYAHSTDGDVILLSPACASWDQFKTFEERGDIFIQAVHKLI
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DMRT1_TRASC
Sequence: GHKRFCMWRDCQCKKCSLIAERQRVMAAQVALRRQQAQEEELGISHPIPLPSAPKLFVKKENNGGSSCLLLESSSPTHSTNTATTASTTPSEGRMLIQDIPSITSRGHLESTSDLVVDSTYYSSFYQPSLYPYYNNLYNYSQYQMAVASDSSSSDMGGTLAGSPVKNSLRSLPATYMSSQSGNQWQMKSTESRHAMSSQYRMHSY
What is the function of this protein?
May be required for testis development.
What are the official names of this protein?
Doublesex- and mab-3-related transcription factor 1.
What is the protein family that this protein belongs to?
Belongs to the DMRT family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PP1B_XENTR
Sequence: MADGELNVDSLISRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYGGLNSGRPVTPPRTANPPKKR
What is the function of this protein?
Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets.  Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis.  Involved in regulation of ionic conductances and long-term synaptic plasticity (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase PP1-beta catalytic subunit, PP-1B.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RAD9_SCHPO
Sequence: MEFTVSNVNLRDLARIFTNLSRIDDAVNWEINKNQIEITCLNSSRSGFSMVTLKKAFFDKYIFQPDSVLLTGLMTPTIRIRTQVKPILSVFRNKIFDFIPTVVTTNSKNGYGSESASRKDVIVENVQISISTGSECRIIFKFLCKHGVIKTYKISYEQTQTLHAVFDKSLSHNNFQINSKILKDLTEHFGQRTEELTIQPLQERVLLTSFTEEVVHNRDILKQPTQTTVSIDGKEFERVALNEGVSVTLSLREFRAAVILAEALGSSICAYYGVPGKPILLTFAKGKNSEIEAQFILATVVGSDEQEVSSMMGNRWQHSSTPASLFNSVERNNSLTAVAHNPPGSIGWQTDQSDSSRMFNSALDRSDETNGIKEPSTTNDAGQSLFLDGIPNESELAAFNNDVNDDAEFGPTQAEQSYHGIFSQED
What is the function of this protein?
Acts in DNA repair and mutagenesis.  Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.  Repressor of entry into mitosis that is activated by chromosome breaks.
What are the official names of this protein?
DNA repair protein rad9.
What is the protein family that this protein belongs to?
Belongs to the rad9 family.
Protein: ATPB_PROWI
Sequence: MTVFIETQNFGTITRIIGPVLDITFTGNKMPKIYHALSIIDKNSEGLDIFIVCEVQQLLGDHCVRAISMNATDGLKRGMTVFDTGDVLKVPVGRSTLGRIFNVLGETIDNLGPADTSNQLPIHRSAPKFIDLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKTHGGVSVFGGVGERTREGNDLYMEMKESGIINEALISESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVSSQDVLLFIDNIFRFLQAGSEVSALLGRLPSAVGYQPTLASEMGALQERITSTKDGSITSIQAVYIPADDLTDPAPATTFAHLDATTVLSRGLASKGIYPAVDPLESTSTMLQPWIVGEEHYKCSQNVKQTLQRYKELQDIIAILGLDELSPDDRLIVARARKIERFLSQPFFVAELFTGLPGKYVSLAKTIQGFNLILSGDLDALSEQAFYLVGDIEEAISKGFLKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits (By similarity).
What are the official names of this protein?
ATP synthase subunit beta, plastid, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid membrane; Peripheral membrane protein.
Protein: ARLY_BACP2
Sequence: MKKLWGGRFQKTPEKWVDEFGASIHFDKQLVKEDLTGSLAHASMLNTCGILDDEEAATIKDGLNKLMKKAEADELEFSVDYEDIHLNLEKMLIDEIGPLGGKLHTARSRNDQVATDMHLYLNNQVEHIIELISSFQTVLVEKAEQHVETIFPGYTHLQRAQPISFAHHMLAYFWMLERDKARFQDSLKRINVSPLGCGALAGTTFPIDREYTAELLGFDHIYENSLDGVSDRDFILEFLSNSSLVMMHLSRLCEEIILWCSQEFKFIELDDTYATGSSMMPQKKNPDMAELIRGKTGRVYGNLMGLLTIMKGLPLTYNKDLQEDKEGMFDTVKTIAGSLQIFTGMIQTMTVNEDVMKKATKEDFSNATEVADYLAKKGMPFREAHEIVGKLVYTCIQEGIYLSDLPFETFTEASDLFEEDIYTVLDPYVAVEKRTSAGGTGFKQIQLALEKAKACLA
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTD_PSEP1
Sequence: MRGLLQRVRGARVEVAGEVVGAIDQGLLVLVAVEPEDSREQADKLLHKLLNYRVFSDEQGKMNLSLKDVGGGLLLVSQFTLAADTRNGMRPSFSTAAPPALGAELFDYLLQQAKAQHADVASGRFGADMQVHLVNDGPVTFMLQI
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_METBU
Sequence: MNAIRYPFITEKAMMLMDENKLQFVVDTRANKTQVENDVVKMYGFTVKSVCTMTTMKGLKKALVTFNETDAAHEIATRIGLV
What is the function of this protein?
Binds to 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: PHR_STRGR
Sequence: MSVAVVLFTSDLRLHDNPVLRAALRDADEVVPLFVRDDAVHRAGFDAPNPLAFLADCLAALDAGLRHRGGRLIVRRGEAATEVRRVAEETGAARVHIAAGVSRYAARREQRIREALADSGRELHVHDAVVTALAPGRVVPTGGKDHFAVFTPYFRRWEAEGVRGTQTAPRTVRVPDGVASDPLPDRDCVENLSPGLARGGEEAGRKLVTSWLNGPMADYEDGHDDLAGDATSRLSPHLHFGTVSAAELVHRAREKGGLGGEAFVRQLAWRDFHHQVLADRPDASWSDYRPRHDRWRSDADEMHAWKSGLTGYPLVDAAMRQLAHEGWMHNRARMLAASFLTKTLYVDWREGARHFLDLLVDGDVANNQLNWQWVAGTGTDTRPNRVLNPVIQGKRFDARGDYVRGWVPELAEVEGSAIHEPWKLQGLDRAGLDYPDPVVDLAEARARFERARGLD
What is the function of this protein?
Involved in repair of UV radiation-induced DNA damage.  Catalyzes the light-dependent monomerization (300-600 nm) of cyclobutyl pyrimidine dimers (in cis-syn configuration), which are formed between adjacent bases on the same DNA strand upon exposure to ultraviolet radiation.
What are the official names of this protein?
Deoxyribodipyrimidine photo-lyase, DNA photolyase, Photoreactivating enzyme.
What is the protein family that this protein belongs to?
Belongs to the DNA photolyase class-1 family.
Protein: BINA1_LYSSH
Sequence: MRNLDFIDSFIPTEGKYIRVMDFYNSEYPFCIHAPSAPNGDIMTEICSRENNQYFIFFPTDDGRVIIANRHNGSVFTGEATSVVSDIYTGSPLQFFREVKRTMATYYLAIQNPESATDVRALEPHSHELPSRLYYTNNIENNSNILISNKEQIYLTLPSLPENEQYPKTPVLSGIDDIGPNQSEKSIIGSTLIPCIMVSDFISLGERMKTTPYYYVKHTQYWQSMWSALFPPGSKETKTEKSGITDTSQISMTDGINVSIGADFGLRFGNKTFGIKGGFTYDTKTQITNTSQLLIETTYTREYTNTENFPVRYTGYVLASEFTLHRSDGTQVNTIPWVALNDNYTTIARYPHFASEPLLGNTKIITDDQN
What is the function of this protein?
Component of a binary toxin active against Culex and some Aedes mosquito larvae; about 1000-fold more toxic against C. quinquefasciatus than A. aegypti (Probable) (Ref. 10, PubMed:8419297).  This subunit alone is active against C. quinquefasciatus, Anopheles gambiae, A. stephensi and Aedes aegypti mosquito cell lines; non Culex mosquitoes are less sensitive to the toxin (PubMed:2886104) (Probable).  Binary toxin internalization into host gut cells requires both proteins (By similarity).
What are the official names of this protein?
Binary larvicide subunit BinA, 41.9 kDa insecticidal toxin, Binary paracrystalline larvicide subunit BinA.
What is the protein family that this protein belongs to?
Belongs to the toxin_10 family.
What are the subcellular locations of this protein?
Spore, perispore.
Protein: GRK6_MOUSE
Sequence: MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQPIGRLLFREFCATRPELTRCTAFLDGVSEYEVTPDEKRKACGRRLMQNFLSHTGPDLIPEVPRQLVSNCAQRLEQGPCKDLFQELTRLTHEYLSTAPFADYLDSIYFNRFLQWKWLERQPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVRNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVAEEYTDRFSSQARSLCSQLLSKDPAERLGCRGGGAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDIEQFSTVKGVDLEPTDQDFYQKFATGSVSIPWQNEMVETECFQELNVFGLDGSVPPDLDWKGQPTAPPKKGLLQRLFSRQDCCGNCSDSEEELPTRL
What is the function of this protein?
Specifically phosphorylates the activated forms of G protein-coupled receptors.  Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization.  Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis (By similarity).  Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor, LRP6 during Wnt signaling (in vitro) (By similarity).
What are the official names of this protein?
G protein-coupled receptor kinase 6, G protein-coupled receptor kinase GRK6.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
What are the subcellular locations of this protein?
Membrane; Lipid-anchor.
Protein: COX1_ANAPL
Sequence: MTFINRWLFSTNHKDIGTLYLIFGAWAGMIGTALSLLIRAELGQPGTLLGDDQIYNVIVTRHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: YJBT_ECOUT
Sequence: MKRNLIKVVKMKSYFAALMLSVSVLPAYAGPLGTADKADLPQSNVSSPMMAQSLRQPDLQPISTDRKTECFRLYTPDRKPGVNCVPDGSTGH
What are the official names of this protein?
Uncharacterized protein YjbT.
What is the protein family that this protein belongs to?
Belongs to the YjbT family.
Protein: VATA_BORHD
Sequence: MEARGKVVGVIGNLVTIEVVGTVSMNEIVFIKTGGRSLKAEIIRIRDGEVDAQVFEMTRGIAVGDDIEFTNKLLTVELGPGLLSQVYDGLQNPLPELAAQCGFFLERGLYLSALDRKKKWHFNATAKVGDIVVAGDFLGFVIEGTIKHKIMIPFDRRDSYSIVEIVSDGDYTIDDKIAVVENDAGGKHIITMSFHWPVKIPITNYKERLIPSEPMVTQTRIIDTFFPVAKGGTFCIPGPFGAGKTVLQQVTSRNADVDIVIIAACGERAGEVVETLKEFPELIDPRTGKSLMERTCIICNTSSMPVAAREASVYTAITIGEYYRQMGLDILLLADSTSRWAQAMREMSGRLEEIPGEEAFPAYLESVIASFYERAGIVVLNDGSFGSVTVGGSVSPAGGNFEEPVTQATLKVVGAFHGLTRERSDARKFPAINPLESWSKYRGVVEFGKTEYARDFLAKGNEINQMMKVVGEEGISNGDFLVYLKSELLDSCYLQQNSFDSVDAAVNPERQNYMFDMLYDILQSDFKFESKLEARGFINELRQNILDMNLTPFKEEKFNKLEVSLKNLVRSKKLDFRGA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type alpha chain is a catalytic subunit.
What are the official names of this protein?
V-type ATP synthase alpha chain, V-ATPase subunit A.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: TBA2_CHLRE
Sequence: MREVISIHIGQAGIQVGNACWELYCLEHGIQPDGQMPSDKTIGGGDDAFNTFFSETGAGKHVPRCIFLDLEPTVVDEVRTGTYRQLFHPEQLISGKEDAANNFARGHYTIGKEIVDLALDRIRKLADNCTGLQGFLVFNAVGGGTGSGLGSLLLERLSVDYGKKSKLGFTVYPSPQVSTAVVEPYNSVLSTHSLLEHTDVAVMLDNEAIYDICRRSLDIERPTYTNLNRLIAQVISSLTASLRFDGALNVDITEFQTNLVPYPRIHFMLSSYAPIISAEKAYHEQLSVAEITNAAFEPASMMVKCDPLHGKYMACCLMYRGDVVPKDVNASVATIKTKRTIQFVDWCPTGFKCGINYQPPTVVPGVDLAKVQRAVCMISNSTAIGEIFSRLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDFEEVGAESAEGAGEGEGEEY
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin alpha-2 chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: KAD1_SOLTU
Sequence: MAAMIRLFRSSSSSSSNSISLISRSLSTAAASETVKSQSYPHNPHSTSVDPKAKTVQWVFLGCPGVGKGTYASRLSTLLGVPHIATGDLVRDELKSSGPLSKQLAEIVNQGKLVSDEIILNLLSKRLESGEAKGEAGFILDGFPRTVRQAEILTEVTDIDLVVNLKLPERVLVEKCLGRRICSECGKNFNVASIDVAGENGAPRISMARLNPPFTVCFKLITRADDTEAIVKERLSIYWDKSQPVEDFYRSQGKLLEFDLPGGIPESWPKLLEVLNLDEQEYKLSPAA
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAA_MOUSE
Sequence: MALCNGDSKPENAGGDLKDGSHHYEGAVVILDAGAQYGKVIDRRVRELFVQSEIFPLETPAFAIKEQGFRAIIISGGPNSVYAEDAPWFDPAIFTIGKPILGICYGMQMMNKVFGGTVHKKSVREDGVFNISMDNTCSLFRGLQKEEIVLLTHGDSVDKVADGFKVVARSGNIVAGIANESKKLYGVQFHPEVGLTENGKVILKNFLYDIAGCSGNFTVQNRELECIREIKEKVGTSKVLVLLSGGVDSTVCTALLNRALNQDQVIAVHIDNGFMRKRESQSVEEALKKLGIQVKVINAAHSFYNGTTTLPISDEDRTPRKRISKTLNMTTSPEEKRKIIGDTFVKIANEVIGEMSLKPEEVFLAQGTLRPDLIESASLVASGKAELIKTHHNDTELIRKLREEGKVIEPLKDFHKDEVRILGRELDLPEELVSRHPFPGPGLAIRVICAEEPYICKDFPETNNILKIVADFSASVKKPHTLLQRVKACTTEEDQEKLMQITSLHSLNAFLLPIKTVGVQGDCRSYSYVCGISSKDEPDWESLIFLARLIPRMCHNINRVVYIFGPPVKEPPTDVTPTFLTTGVLSTLRQADFEAHNILRESGFAGKISQMPVILTPLHFDRDPLQKQPSCQRSVVIRTFITSDFMTGVPATPGNEIPVEVVLKMVTEIKKIPGISRIMYDLTSKPPGTTEWE
What is the function of this protein?
Catalyzes the conversion of xanthine monophosphate (XMP) to GMP in the presence of glutamine and ATP through an adenyl-XMP intermediate.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RS18_BRUA1
Sequence: MVDINQIPTRRPFHRRRKTCPFSGANAPKIDYKDVKLLQRYISERGKIVPSRITAVSQKKQRELAKAIKRARFLGLLPYVVK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: ATP6_ELUMP
Sequence: MIEEILTHHIIDHKLTYKLFGVIPLSSNLITLFCITIGVFILFTLIAKFRRPVLLMTAIEGLVVFIRDEIVVANFGEHGKKLTPYFCTLFIFLLFSNSLGMIPQMRTITGSISVTIGMALTSLSLIIFLGVKQNGLLGYLKHFVPEGTPWFLAPLLFFLEILGLFTKTAALALRLFANMIAGHMVIICFICLIFIMTAINKYAGIFTAIPSTGLSLFVNLLEVLVILIQTYVFTLLTAIFAGEAYAHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SEQA_PHOPR
Sequence: MKSIEVDEELYRYIASQTQHIGESASDILRRLLMVPAEQQLEVVVPVRPKGIIVSKDAGNEHKLDRVKEMRTLLISDEFAVQGKAIGRFMMILSSLYRIDSDGFIEAAAIKGRTRVYFADNEEALLASGKTTKPKAIPETPYWVITNTNTDRKRQMVDQLMVKMNYNTDIIEKVCGVI
What is the function of this protein?
Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle.  Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins.  Repression is relieved when the region becomes fully methylated.
What are the official names of this protein?
Negative modulator of initiation of replication.
What is the protein family that this protein belongs to?
Belongs to the SeqA family.
What are the subcellular locations of this protein?
Cytoplasm.