PharMolix/UniProtQA huggingface dataset:
Protein: G1094_PHOV8
Sequence: MKKIKLLLVAGACVVLSACSPQAPTVHTTDKGTQWEWNEGTIVVKSPERPAGQKSVIGLTAPKMEVVRVGFVGLGMRGPGAVSRFTHIPGTQIVALCDYDPKRAEACQNILKKASMPKAAIYSGETGYEELCKRDDIDLVYIAADWLHHFPIAKCALENGKHVAIEVPSAMNLQECWDLVNLSETTRKHCFILENCCYDWFEMNTLNMAQNGVFGEVIRAQGAYIHNLSDFWDYYWKNGENDKLGWRLEFNMRHRGDVYATHGLGPVAQVLDIHRGDRMKTLTAMDTKSVVGKGLVEAKTGSECTNFRNGDHTTTMIRTENGKVIEIQHNVMTPQPYNRLYQLTGVKGFANKYPTEGYALGADQLSASGVQPKVDNLSSHGFLPQAEMDALVEKYQHPILKKYGEIAKEVGGHGGMDFIMDSRLVYCLQNGLPLDMDVYDLAEWCALAELGEISMDNNCAAVEFPDFTRGEWNVVKGYKHAYASPEEEQASMEKAKAFTAKLKERGAKEWATEADK
What is the function of this protein?
Glycosidase.
What are the official names of this protein?
Glycosyl hydrolase family 109 protein 4.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: INH1_TABYA
Sequence: MTSILVSRFLIAALVLQYATSDAVNYCRLPCRGCDYHVGCGEPAYAQECGQSPRTRELLKEHRNEILSKINDVRDHVAKGSWGLPMAARMKVVVWDAELAGLAKRHTKGCVGETHACRNTERFWLPGQLNFKYSGDKLPRIRELIDDAVKKGHLQKHNITREFIENYRENGPNGNVKGLALAISDRVTAVGCGLTTWEDGAKARALLTCNFSSQNIRGRPVYKIGNSPGEKCIEKDETYKNLCSATEPIDPNKSN
What is the function of this protein?
Inhibits platelet aggregation induced by all agonists tested (By similarity).  May act by competing with fibrinogen for binding to glycoprotein IIb/IIIa (ITGA2B/ITGB3) (By similarity).
What are the official names of this protein?
Tabinhibitin 1, Macquaritin 1.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Secreted.
Protein: PRM1_ASPTN
Sequence: MLFSRPGRSIFPLLPPYGAHDPNGGRRIIPLNPDGITPYLGLRSRLSQVWLNRWTILLLLVLARVLIAVAGMQSDMGSAKREALSACTSVESMGSAMVSMPHYLSQGVNELTAAGVEKAVSALKTMLLLTITGVEELILFFIKVMYQTYLCLFTMVVRGSVHLALGVVEDAADFLNSTVKSIGQDIHKSVDSFESSLNSFIDDINGIASALLGEIPKLDISDKLDKLDSLSLPSSIDSTIDKVNNSIPTFDEVDKYVTNILRTPFEEVKRLVNGSLSNYTFDRSALPVPAKEQLSFCDGSDGINSFFDKVAHITTTARTIFIAVLIIAAVLVCVPVGWQEIRRWRTMKERSQLVHKDAHDPMDVVYIVSRPYTAATGVKAASRFSNSRRQILVRWVIAYATSPPALFVLCLALAGLFSCLCQYILLKAVERTVPELTSEVGQFAGKVVDKLQDTSAKWAADANSAIADTNTDLNKNIFGWVNTSTTAVNDTLDAFVEKTTGVLNDTFGDTVLSGPVQEVYDCLIGLKVEAVQKALTWVHDHAHIDFPLLPNDTFSRGAADSISDGSSNPSDSFLADADDQTSNKITEVVFRVTDKIEEGIRTETVISAVILLVWVVNALIGVLRALSLFWSRERTRGEGGGGAPMPAAPADSHGFVDVPLTAIPDVASHSQPAPRYEGPAPALAVSRDIPYGDEKLGSVGQKALHVDGISDLRGSSYVEYGMEKR
What is the function of this protein?
Involved in cell fusion during mating by stabilizing the plasma membrane fusion event.
What are the official names of this protein?
Plasma membrane fusion protein prm1.
What is the protein family that this protein belongs to?
Belongs to the PRM1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HIS3_CLAM3
Sequence: MSAPAPVPDVDGVLARASFADDGLLPAVIQQHDTREVLMLGYMDREALRRTLTTGRVTFWSRSRREYWRKGDTSGHGQYVRDAALDCDGDTVLIQVDQVGVACHTGTRTCFDADHLHPVTGARPAADEGPTP
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACKA_FRATO
Sequence: MSEILVLNCGSSSVKFALINPHTSQSLVTGLAENIATKNCKVVFKAEHKIEKYLENGSYKDVFEMLKDFLVENKHLEKIVAIGHRVVHGGQYFSKSVLINADSLEKIKACIALAPLHNPAHIEGIRFCQQIFPELPQVAVFDTAFHQTVPSYIAEYAIPYELTHKHNIRKYGAHGTSHKYVSEQAAKILTQQKANVIVAHLGNGCSITAVVDGKSIDTSMGLTPLDGLVMGTRSGCIDPSIFAYIISDNLGWSVTEITNMLNKQSGLLGICGHNDMREVSQLAAKGDSLAKLAIEIFSHRVAKFVASYMIYFNKLDALVFTGGIGENAANIRKNIISKLANLGFMIDHQKNSNSETFINSKNSHNIMVIATNEELMIAQETQNLI
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y458_BACCZ
Sequence: MGEENQPNYTISQENWSLHRKGYDDQQRHQEKVQEAIKNNLPDLVTEESIVMSNGKDVVKIPIRSLDEYKIRYNYDKNKHVGQGNGDSKVGDVVARDGSGGQKQKGPGKGQGAGDAAGEDYYEAEVSILELEQAFFKELELPNLKRKEMDENRIEHVEFNDIRKTGLWGNIDKKRTMISAYKRNAMRGKASFHPIHQEDLKFRTWNEVLKPDSKAVVLAMMDTSGSMGIWEKYMARSFFFWMTRFLRTKYETVDIEFIAHHTEAKVVPEEEFFSKGESGGTICSSVYKKALELIDNKYSPDRYNIYPFHFSDGDNLTSDNARCVKLVEELMKKCNMFGYGEVNQYNRHSTLMSAYKNIKDENFRYYILKQKADVFHAMKSFFREESGEKMA
What are the official names of this protein?
UPF0229 protein BCE33L0458.
What is the protein family that this protein belongs to?
Belongs to the UPF0229 family.
Protein: APAH_ESCF3
Sequence: MATYLIGDVHGCYDELIALLHKVEFTPGKDTLWLTGDLVARGPGSLDVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRNKPKDRLTPLLEAPDADELLNWLRRQPLLQIDEEKKLVMAHAGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMPNNWSPELRGLGRLRFITNAFTRMRFCFPNGQLDMYSKESPEEAPAPLKPWFAIPGPVAEEYSIAFGHWASLEGKGTPEGIYALDTGCCWGGTLTCLRWEDKQYFVQPSNRHKDLGEGEAVAS
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: RLMC_SHEB9
Sequence: MSAAIVNAVKQCGYFNQGQCLSCRHIQQPLAQQVAVKTQTLLQLLAPFIPANSAELFLPPITGDDSGFRNKAKMVVLGAAHEPVLGIVSPSGEAVDLCDCLLYPADMQALLHRLTRFVQQAGLPPYRVDKAKGELKFILLTRSQVRGEYLLRFVLRSHNGIERIERELPALLAEYPQIKVVSVNIQPVHMAILEGDEEIFLTENTRLEERFNHVPLFIRPKSFFQTNPQVAAQLYQTAREWVAEFSPRSLWDLFCGVGGFGLHCASKDITLTGIEIEAEAIACAQMSAQMMGLENVQFMALDSTDFAKGKSAADKPDLIIVNPPRRGIGEALCQSLSEFAPKAILYSSCNPKTLAKDLEHIQGYHLTKVQLFDLFPHTDHFEVLAMLVKD
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC, 23S rRNA(m5U747)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.
Protein: ENO_PHOLL
Sequence: MSKIVKVIGREIIDSRGNPTVEAEVHLEGGFVGLAAAPSGASTGSREALELRDGDKSRFMGKGVLKAVDAVNGPIAQAVIGQDAKDQANIDKIMIDLDGTENKSQFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKFSMPLPMMNIINGGEHADNNVDIQEFMIQPIGAKTLKEAVRIGSEVFHNLAKVLKAKGMSTAVGDEGGYAPNLESNAAALAAIKEAVEQAGYVLGKDVTLAMDCAASEFYNPETGNYELKGEGKTFTSQEFTHYLEDLTRKYPIVSIEDGLNESDWEGFAYQTKVLGEKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGNRAPFYGLKEVKGQA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: TRX1_EHV2
Sequence: MKTKEVTPRGDSGEKLARDLLRLVPPQTHKLGTFRASELGRDLRAIVANYAPKTISGHIQIFRDDFIAPPYRQPLYGEFLVHAKTFHPQEPRGTFVFAFSVGDGPECTSVDTIFSPVSLFRVCGLGADAAPHTHRISHIWYESESDFLNVAANVRELIENCSLHKFLSPVGPLVQNIQSTFLNKITTVVKGEVLSNRSPPENIKLVLPSDLFFDMDETCPYPPSGDPVKPRVCYYVCILYVMVNNIPSASLQFFRTGKGASDVVFFLRRYYSDAIANKITVLGDNLDINNLTLGAVCMLGYSSSQSTPGRGNLHFRSYSLPTVEVSDFVAQPGSWTLI
What is the function of this protein?
Structural component of the T=16 icosahedral capsid.  The capsid is composed of pentamers and hexamers of major capsid protein/MCP, which are linked together by heterotrimers called triplexes.  These triplexes are formed by a single molecule of triplex protein 1/TRX1 and two copies of triplex protein 2/TRX2.  Additionally, TRX1 is required for efficient transport of TRX2 to the nucleus, which is the site of capsid assembly.
What are the official names of this protein?
Triplex capsid protein 1.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae TRX1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: G6PIA_ORYSJ
Sequence: MASSALICDTEQWKGLQAHVGEIQKTHLRHLMHDVERCKAMTAEYEGIYLDYSRQRATGETMEKLFKLAEAAKLKEKIEKMFRGDKINSTENRSVLHVALRAPRDEVINSNGVNVVPEVWGVKDKIKQFSETFRSGSWVGATGKALTNVVSVGIGGSFLGPLFVHAALQTDPEAAESAKGRQLRFLANVDPVDVARSIKDLDPETTLVVVVSKTFTTAETMLNARTLKEWIVSSLGPDAVAKHMIAVSTNLELVEKFGIDPKNAFAFWDWVGGRYSVCSAVGVLPLSLQYGFPIVQKFLEGAASIDKHFRSSSFEKNIPVLLGLLSVWNVSFLGYPARAILPYSQALEKFAPHIQQLSMESNGKGVSIDGVQLPFESGEIDFGEPGTNGQHSFYQLIHQGRVIPCDFIGVVKSQQPVYLKGEIVSNHDELMSNFFAQPDALAYGKTPEQLHSEKVPEHLIPHKTFQGNRPSLSLLLPSLSAYEIGQLLAIYEHRIAVQGFLWGINSFDQWGVELGKSLASQVRKSLHASRVEGKPVLGFNSSTTSLLTRYLAVEPSTPYNTTTLPKV
What is the function of this protein?
Catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis.
What are the official names of this protein?
Glucose-6-phosphate isomerase, cytosolic A, GPI-A, Phosphoglucose isomerase A, PGI-A, Phosphohexose isomerase A, PHI-A.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACEK_ANADE
Sequence: MLDERGALARGAAEAIRAGYEAYQAERARITARARGRFEARDWAGAQRDARERLDLRDGVVHRTVGEVRAELGGAVQDREVWRRAKEAFEAVAAARPDAEIAGSFFNSVTRRVLTTVGVDPAIEFLAADAPPPREDPPQHRAFAREATTEALLARILRAAPISAPFEDLARDARLAALELDAHVRGLPDRQPIDAVELARPVFYRGKGAYLVGRIRRGRHLTPLVLALAHGDRGVALDAVLFTEEDVSIVFGFTRSYFHVALERPRAMVAFLSTLLPLKRRSELYTGLGYHKHGKAELYREVAQHLAEGDDRFVPARGDRGLVMCVFTLPGLDVIFKVIRDRFAPPKQTTRREVMDRYRHVFRHDRAGRLVDAQEYEHLAFPAARFSPALLEELRTECGDGVRVAGGEVAIRHLYAERRVTPLNLFVREADEWTARQAVLDFGCALRDLAATDTFPGDLLLKNFGVTRHGRVIFYDYDELTRVTDCNFRDLPGAGPGDGDDGWGGGPDAGYDGGDPPFYVGPADVFPEELLPFLGLTGRLREVFLRAHGELLTGRWWRDIQARLRAGEIVDIFPYREEQRLRHAHP
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OMCBD_CHLTR
Sequence: MNKLIRRAVTIFAVTSVASLFASGVLETSMAESLSTNVISLADTKAKDNTSHKSKKARKNHSKETPVDRKEVAPVHESKATGPKQDSCFGRMYTVKVNDDRNVEITQAVPEYATVGSPYPIEITATGKRDCVDVIITQQLPCEAEFVRSDPATTPTADGKLVWKIDRLGQGEKSKITVWVKPLKEGCCFTAATVCACPEIRSVTKCGQPAICVKQEGPENACLRCPVVYKINIVNQGTATARNVVVENPVPDGYAHSSGQRVLTFTLGDMQPGEHRTITVEFCPLKRGRATNIATVSYCGGHKNTASVTTVINEPCVQVSIAGADWSYVCKPVEYVISVSNPGDLVLRDVVVEDTLSPGVTVLEAAGAQISCNKVVWTVKELNPGESLQYKVLVRAQTPGQFTNNVVVKSCSDCGTCTSCAEATTYWKGVAATHMCVVDTCDPVCVGENTVYRICVTNRGSAEDTNVSLMLKFSKELQPVSFSGPTKGTITGNTVVFDSLPRLGSKETVEFSVTLKAVSAGDARGEAILSSDTLTVPVSDTENTHIY
What is the function of this protein?
In elementary bodies (EBs, the infectious stage, which is able to survive outside the host cell) provides the structural integrity of the outer envelope through disulfide cross-links with the small cysteine-rich protein and the major outer membrane protein.  It has been described in publications as the Sarkosyl-insoluble COMC (Chlamydia outer membrane complex), and serves as the functional equivalent of peptidoglycan (By similarity).
What are the official names of this protein?
Large cysteine-rich periplasmic protein OmcB, Large-CRP, 60 kDa cysteine-rich OMP, 60 kDa outer membrane protein, Cysteine-rich outer membrane protein, CRP.
What are the subcellular locations of this protein?
Periplasm.
Protein: Y413_STAA3
Sequence: MGYLKRLVLYIVIMVMSVFIIGCDKSSDTAEKSKEDSKETQIKKSFAKTLDMYSIKNLEELYDKEGYRDGEFEKGDKGMWTIYTDFAKSNKPGELSNEGMVLYLDRNTRTAKGYYFVRTFYRKDKLPDRKNYKVEMKNNKIILLDKVEDKKLKQKIENFKFFSQYANLKELKNYSNGDVSINENVPSYDVKYKMSNKDENVKQLRSRYNIPTDKSPVLKMHIDGNLKGSSVGDRKLEIDFSKRENSHLSVIDSLDYQPAKTNKDDE
What are the official names of this protein?
Uncharacterized lipoprotein SAUSA300_0413.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal tandem lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: TBCK_MOUSE
Sequence: MFPLKDAEMGAFTFFASALPHDVCGSNGLPLTPNSIKILGRFQILKTITHPRLCQYVDISRGKHERLVVVAEHCERSLEDLLRERKPVSHSTVLCIAYEVLEGLHYLNKHGIVHRALSPHNILLDRKGHIKLAKFGLYHMTAHGDDVDFPIGYPSYLAPEVIAQGIPKTTDHVPSEKPLPSGPKSDVWSLGIILFELCVGRKLFQSLDVSERVKFLLTLGCVDDTIIVLAEEHGCLDIIKELPENVINILKKCLTFHPSKRPTPDELMKDQVFSEVSPLYTPFIKPASLFSSSLRCADLTLPEDISDLCKDIDNDYLAERSIEEVYYLWCLAGGDLEKELINKEIIRSKPPVCTLPNFLFEDGESFGQGRDRSSLLDDTTVTLSLCQLRNRLKDVGGEAFYPLLEDDQSNLPHSNSNNELSAAATLPLIIRERDTEYQLNRIILFDRLLKAYPYKKNQIWKEARVDIPPLMRGLTWAALLGVEGAIHAKYDAIDKDTPIPTDRQIEVDIPRCHQYDELLSSPEGHAKFRRVLKAWVVSHPDLVYWQGLDSLCAPFLYLNFNNEALAYACMSAFIPKYLYNFFLKDNSHVIQEYLTVFSQMIAFHDPELSNHLNEIGFIPDLYAIPWFLTMFTHVFPLHKIFHLWDTLLLGNSSFPFCIGVAILQQLRDRLLANGFNECILLFSDLPEIDIERCVRESVNLFCWTPKSATYRQHAQPPKPASESSVVRSSAPYFSAECTDPPKTDLGNKASPVWKMHCAAPRA
What is the function of this protein?
Involved in the modulation of mTOR signaling and expression of mTOR complex components.  Involved in the regulation of cell proliferation and growth.  Involved in the control of actin-cytoskeleton organization.
What are the official names of this protein?
TBC domain-containing protein kinase-like protein.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, spindle. Midbody. Note=Mainly localized in the cytoplasm during interphase. During metaphase, TBCK accumulates at the mitotic spindle. At the end of mitosis, it is detected at the midbody.
Protein: PRS4_CAEEL
Sequence: MGQQQSGFGGRGNDRGAGDGEKKEKKKYEAPIPSRIGKKKKGSKGPDAASKLPAVTPHARCRLKLLKSERIKDYLLMEQEFIQNQERLKPQEERQEEERAKVDELRGTPMAVGSLEEIIDDQHAIVSTNVGSEHYVNIMSFVDKEQLEPGCSVLLNHKNHAVIGVLSDDTDPMVSVMKLEKAPQETYADVGGLDQQIQEIKEAVELPLTHPEYYEEMGIRPPKGVILYGCPGTGKTLLAKAVANQTSATFLRIVGSELIQKYLGDGPKMVRELFRVAEENAPSIVFIDEIDAVGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVLMATNRIESLDPALIRPGRIDRKIEFPLPDEKTKRRIFQIHTSRMTLGKEVNLEEFITAKDELSGADIKAMCTEAGLLALRERRMRVTMEDFQKSKENVLYRKKEGAPEELYL
What is the function of this protein?
The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins.  The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity).  May play a role in the degradation of microtubule severing protein mei-1 (PubMed:22621901).
What are the official names of this protein?
Probable 26S proteasome regulatory subunit 4.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MNMA_VIBCH
Sequence: MMSVEHSANSQKKVIVGMSGGVDSSVSAYLLKQQGYQVEGLFMKNWEEDDNEEYCTAAEDLADAQAVCDKLGIPLHTINFAAEYWDNVFEYFLAEYKAGRTPNPDILCNKEIKFKAFLEFADEVLDADYIAMGHYVRRTFPQNGEKPQMLRGLDGNKDQSYFLYTLSHEQVARTLFPVGELEKPEVRRIAEEQGLITAKKKDSTGICFIGERKFTDFLSRYLPAQPGKIETPEGKVIGEHQGLMYHTLGQRKGLHIGGMKESSEQPWYVADKDLKRNVLIAVQGADHPLLKSHGLVAAQLHWVDRTPITEPVRCSVKTRYRQSDIACTIIPLSDDRIKVMFDEPQVAVTPGQSAVFYQGEICLGGGIIEERI
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCD_STRT2
Sequence: MGLFDRKEKYIRINPNRYVRNGVDHHVPEVPDDLFAKCPGCKQAIYQKDLGQAKICPNCSYAFRISAKERLDLTVDEGSFQELFTGIKTENPLNFPGYMEKLAATKEKTGLDEAVVTGVATIKGQKTALAIMDSNFIMASMGTVVGEKITKLFEYAILEKLPVVIFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLLYLTVLTDPTTGGVTASFAMQGDIILAEPQTLIGFAGRRVIENTVRETLPDDFQKAEFLQEHGFVDAIVKRTELADTIATLLSFHGGVQ
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IRAP_ECOLU
Sequence: MKNLIAELLFKLAQKEEESKELCAQVEALEIIVTAMLRNMAQNDQQRLIDQVEGALYEVKPDASIPDDDTELLRNYVKKLLKHPRQ
What is the function of this protein?
Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate starvation, but also in stationary phase and during nitrogen starvation.  Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway.
What are the official names of this protein?
Anti-adapter protein IraP.
What is the protein family that this protein belongs to?
Belongs to the IraP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_VIBVY
Sequence: MQVTVETLEGLERRLNITVPAANIEDAVTAELRNIAKNRRFDGFRKGKVPMKMVAKMYGKAVRQDILGEVMQRHFIEAIIKEKINPAGAPTFAPVENKEGSDLVFNATFEVYPEVELKGLENITVEKPAVEVKDADVEEMIETLRKQQATWTEVEEAAEAGKRVSIDFVGSIDGEEFEGGKAENFPLEMGAGRMIPGFEDGIEGKTKGMEFEIDVTFPEDYHAENLKGKAAKFAIKVNKVEARQLPELNDEFVAKFGVAEGGIDALKAEVRKNMERELKQAVKNRIKEQAIDGLVKENEIDVPAALIDQEINVLRQQAAQRFGGNVEAAMQLPRELFEEQAKRRVVVGLLLGEVIKAHELKVDEEKVKAIITEMATAYEDPTEVVTYYEQNEQMMNNMRNVALEEQAIDAIIAKAQVSEKEVSFNELMNQPA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: LCL2_ASPFC
Sequence: MLSSWVRCLGALLFLASVAQAQFQFFEHMFGGGHQEHHQQNTQNSASDSARYQQLWEGTNCNKYLCPGTLACVDFPHHCPCAHPNVEDKVELGEGSAVCISKGGYKPGEAARKIELARKGLL
What is the function of this protein?
Probable component of the endoplasmic reticulum-associated degradation (ERAD) pathway.
What are the official names of this protein?
Long chronological lifespan protein 2.
What is the protein family that this protein belongs to?
Belongs to the LCL2 family.
Protein: ARMC2_BOVIN
Sequence: MLSPNDKKLEKLDPFYLPSLSKQKTSAEIVSEARNALRTVRTQRPFTPREDQRKLFGPASSRTPENRPPSSFSVHASSFEFSDSRPISGTRLSPLEFKPKAPASPDTVEDFCLSFPKPPVDPAKIRRISSARARLFRVASQGALLPARTLLPTQPTRVESEETVTTRDSVVKINGIYLTESKAIGHLKRHPLQLTYDGDFSKITEQEMFKGATSVPFHLRSGGDQGKRRPRASSSSRSPDQSRLDIRAGSKADLQEKNTEIEVDEVFWNTRIVPILHDLEKEENIEMVCATCTQLHHALEEGNMLGNKFKRRSVLLKTLYKLVDVGSDLLSLKLAKIILALKVSGKNLLNVCKLIFKISRSEKNDSLIRNDSILESLLEVLRSEDLQANTEAFLYCMGTIKFISGNPEFLHEMMGKGAVEILMSLIKQVNENTKKSGTCLPNSGHLLVQMTATLRNLVDSPLARSKLLSINALPQLCTVMEQHIGDKDVCTNIARIFSKLTSYHDCCVALASYSRCYALFLNLINKYQKKQDLVVRVVFILGNLTAKNNQAREQFSKEKGSIPTLLSLFHTFYKLDLHSGKRWGEGDERPEARRPAQAEDVLIKLTRVLANLAIHPGVGPAIAAHSHIVGLLLATLESKSIDDCEELVINTTATINNLSYYKVKNSIIQDRKLYIAELLLKLLVSNNMDGILEAVRVFGNLSQDHDICDFIVQKNVHKFMIALLDAKHQDICFSACGVLLNLTVDRDKRLILKEGGGIKKLVDCLRDFGPTDWQLASLVCKTLWNFSENITNAASCFGDEAANTLLALLSSFLDEELALNGSFDQDLKNYHKLHWETEFRPVAQQLLNRIKNHHTFLEPLPIPSF
What is the function of this protein?
Required for sperm flagellum axoneme organization and function.  Involved in axonemal central pair complex assembly and/or stability.
What are the official names of this protein?
Armadillo repeat-containing protein 2.
Protein: MLR_SPISA
Sequence: SDDKKAKAATSSVLTKFTQNQIQEMKEAFTMIDQNRDGLIDVSDLKEMYSNLGTAPQDSVLQAMVKEAPQMNFTGFLSLFSEKMSGTDPEETLRNAFQMFDSDNTGYIPEEYMKDLLENMGDNFSKDEVRQTWKEAPIAGGKVDYNAFVSKIKGKEQDDA
What is the function of this protein?
In molluscan muscle, calcium regulation is associated with myosin rather than with actin.  Muscle myosin contains two types of light chains: the catalytic light chain, essential for ATPase activity, and the regulatory light chain, a calcium-binding protein responsible for Ca(2+) dependent binding and Ca(2+) dependent Mg-ATPase activity.
What are the official names of this protein?
Myosin regulatory light chain, smooth muscle.
Protein: ILVC_CERS1
Sequence: MRVYYDRDCDINLIKDKKVAILGYGSQGHAHALNLRDSGAKNVVVALREGSPSAKKAEAEGLKVMGIAEAAAWCDLIMFTMPDELQAETYKKYVHDNLREGSAIAFAHGLNVHFGLIEPKPGVDVIMMAPKGPGHTVRGEYVKGGGVPCLVAVHNDATGKAMEIGLSYCSAIGGGRSGIIETNFRQECETDLFGEQAVLCGGLVELIRMGFETLVEAGYEPEMAYFECLHEVKLIVDLIYEGGIANMNYSISNTAEYGEYVSGPRILPYEETKARMKAVLTDIQTGKFVRDFMQENAVGQPFFKATRRINDEHQIEQVGEKLRGMMPWISKGKMVDRARN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: SODF_SALTI
Sequence: MSFELPALPYAKDALAPHISAETLEYHYGKHHQTYVTNLNNLIKGTAFEGKSLEEIVRTSEGGIFNNAAQVWNHTFYWNCLAPNAGGEPTGKLADAIAASFGSFAEFKAQFTDAAIKNFGSGWTWLVKSADGKLAIVSTSNAGTPLTTDATPLLTVDVWEHAYYIDYRNARPNYLEHFWALVNWEFVAKNLAA
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Fe].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: NDHK_SPIOL
Sequence: MNSIEFPLLDQIAQNSVISTTSNDLSNWSRLSSLWPLLYGTSCCFIEFASLIGSRFDFDRYGLVPRASPRQADLILTAGTVTMKMAPSLLRLYEQMPEPKYVIAMGACTITGGMFSTDSYSTVRGVDKLIPVDVYLPGCPPKPEAVIDAITKLRKKISREIYEDRIKSQPKNRCFTINHKFRVGRSIHTGNYDQALLYKYKSPSTSEIPPETFFKYKNAASSRELVN
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit K, chloroplastic, NAD(P)H dehydrogenase subunit K, NADH-plastoquinone oxidoreductase subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.