PharMolix/UniProtQA huggingface dataset:
Protein: PPR37_HUMAN
Sequence: MEIAPQEAPPVPGADGDIEEAPAEAGSPSPASPPADGRLKAAAKRVTFPSDEDIVSGAVEPKDPWRHAQNVTVDEVIGAYKQACQKLNCRQIPKLLRQLQEFTDLGHRLDCLDLKGEKLDYKTCEALEEVFKRLQFKVVDLEQTNLDEDGASALFDMIEYYESATHLNISFNKHIGTRGWQAAAHMMRKTSCLQYLDARNTPLLDHSAPFVARALRIRSSLAVLHLENASLSGRPLMLLATALKMNMNLRELYLADNKLNGLQDSAQLGNLLKFNCSLQILDLRNNHVLDSGLAYICEGLKEQRKGLVTLVLWNNQLTHTGMAFLGMTLPHTQSLETLNLGHNPIGNEGVRHLKNGLISNRSVLRLGLASTKLTCEGAVAVAEFIAESPRLLRLDLRENEIKTGGLMALSLALKVNHSLLRLDLDREPKKEAVKSFIETQKALLAEIQNGCKRNLVLAREREEKEQPPQLSASMPETTATEPQPDDEPAAGVQNGAPSPAPSPDSDSDSDSDGEEEEEEEGERDETPCPALVPPTDSLGPGDRSPPGSPSTPTEQRISVSSPGRGHKVFVVTRVESPPERAEPPASPTPPSPPPPPSPPASPSLPPAGAIDTRDTGSSEPQPPPEPPRSGPPLPNGLKPEFALALPPEPPPGPEVKGGSCGLEHELSCSKNEKELEELLLEASQESGQETL
What is the function of this protein?
Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes.
What are the official names of this protein?
Protein phosphatase 1 regulatory subunit 37, Leucine-rich repeat-containing protein 68.
What is the protein family that this protein belongs to?
Belongs to the PPP1R37 family.
Protein: CAPG_BOVIN
Sequence: MYSPIPQSGSPFPPTVKLPGLHIWRVEKLKPVPVAPENYGIFFSGDSYLVLHNGPEELSHLHLWIGQQSSRDEQGGCAILAVHLNTLLGERPVQHRESQGNESDLFMSYFPHGLKYQEGGVESAFHKTSPGTAPAAIKKLYQVKGKKNIRATERVLSWDSFNTGDCFILDLGQNIFAWCGAKSNILERNKARDLALAIRDSERQGKAHVEIVTDGEEPADMIQVLGPKPSLKEGNPEEDLTADRTNAQAAALYKVSDATGQMNLTKLADSSPFALELLIPDDCFVLDNGLCGKIYIWKGRKANEKERQAALQVAEDFITRMRYAPNTQVEILPQGRESAIFKQFFKDWK
What is the function of this protein?
Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments.  May play an important role in macrophage function.  May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin.  May bind DNA (By similarity).
What are the official names of this protein?
Macrophage-capping protein, Actin regulatory protein CAP-G.
What is the protein family that this protein belongs to?
Belongs to the villin/gelsolin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Melanosome. Cell projection, lamellipodium. Cell projection, ruffle. Note=In macrophages, may be predominantly cytoplasmic. Nuclear localization was observed in fibroblasts. In macrophages, present at the membrane-cytoplasm interface. In activated macrophages, concentrated in the ruffles of the leading lamellipodia.
Protein: HEMT_THEHE
Sequence: GFPIPDPYGWDPSFRTFYSIIDDEHKTLFNGIFHLAIDDNADNLGELRRCTGKHFLNQEVLMQASQYQFYDEHKKAHEEFIRALDNWKGDVKWAKSWLVNHIKTIDFKYKGKI
What is the function of this protein?
Hemerythrin is a respiratory protein in blood cells of certain marine worms.  The oxygen-binding site in each chain contains two iron atoms.
What are the official names of this protein?
Hemerythrin.
What is the protein family that this protein belongs to?
Belongs to the hemerythrin family.
Protein: LSRD_YERE8
Sequence: MNIYRRYGWELALAALLVLEIGLFGLSNSRMLDINVLLFSTSDFICIGIVALPLTMVIVSGGIDISFGSTIGLCSIFLGVMFQAGVPMSIAIPLTLLVGALCGLINAGLILYTGVNPLVITLGTMYLFGGSALLLSGISGATGYEGIGGFPTAFTDFANQTLLGLPVPLVIFMVCVLLFWLLMHRTHSGRNVFLIGQNSRVARYSALPVARTLCLLYALTGMASAIAAVLLVSYFGSARSDLGASFLMPAITAVVLGGANIYGGSGSILGTALAVLLVGYLQQGLQMIGTPNQISSALSGALLILVVVGRSISLHRHLIYEWLQRRRNTVV
What is the function of this protein?
Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import.  Probably responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
Autoinducer 2 import system permease protein LsrD, AI-2 import system permease protein LsrD.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LIPA_BACC7
Sequence: MTKQTEYKRKPEWLKIKLNTNENYTGLKKMMRSKNLHTVCEEAKCPNIHECWAVRKTATFMILGAVCTRACRFCAVKTGLPTELDLQEPERVADSVVQMGLKHVVITAVARDDLKDGGAAVFAETVRAVRRKNPFTSIEVLPSDMGGVEENLKMLMDAKPDILNHNIETVRRLSDRVRARAKYDRSLEFLRRAKEMQPDIPTKSSIMVGLGETREDLIEAMDDLRANNVDILTLGQYLQPSKKHLPVLKYYPPAEFAELKEIALSKGFSHCEAGPLVRSSYHADEQVRSAKENTAEAK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDDD_ALCXX
Sequence: MTDRSTLDDAPAQADFIIAGATLIDGGGGPARQGDLAVRGGRIVALGDFAHAPGVPVIDARGLALAPGFIDSHTHDDGYLLAHPEMLPKVSQGITTVVTGNCGISLAPLSRRQIPQPLDLLGPPELFRFATFRDWLRALAETPAAVNVIPLVGHTTLRVAVMDDTGRAATDAERAAMRALLDEALQAGAFGVSTGTFYPPASAAPTDEIIDVCQPLRGRAGAIYATHLRDEADHIVPAMEEALLIGRELDCRVVFSHHKLAGERNHGRSRETLDMISRAAATQRVCLDCHPYPATSTMLRLDRARLASRTLITWSKGYPEATGRDFSEVMAELGLDDEAAIARLAPAGAIYFLMDQADVNRIFSHPLTTVGSDGLPFDPHPHPRQWGTFTNVLRTMVREQRLLSLETAIHKMTGLAAAQYGLTERGLLRQGYHADLVLFDPANVTDTATFSAPIQVSQGIHAVWVNGRQVWDGERTGAERPGQVLAPGDAIPWSQQSE
What are the official names of this protein?
N-acyl-D-aspartate deacylase, N-acyl-D-aspartate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. N-acyl-D-amino-acid deacylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1393_GRABC
Sequence: MSAKQDDTQPIQAASKRLLKVILEGEALTRLSPLQEMDRAQAVADLEAENVFSLERPLPGMTPVSEQGPYVLHLSIQEGRLIFDIRRQDDTFLTVLALALGPFRRLIKDYHLLVDSYVKAVQEAREARIQAIDMGRRGLHNEGAELMRHRLNGKISIDFETARRLFTLVCVLHQRI
What are the official names of this protein?
UPF0262 protein GbCGDNIH1_1393.
What is the protein family that this protein belongs to?
Belongs to the UPF0262 family.
Protein: SSRP_ARTS2
Sequence: MPKESGRKVVATNRKARHDYHVLDTYEAGIALMGTEVKSLREGHASMVDGFCTFYNDELWMEGIHIPEYNQGSWTNHSARRRRKLLLHREELTKISHKIRESGFTIVPLQLYFLDGKAKVEIGVARGKKEYDKRQTLREQQDKREALRVMRERNRG
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: AMPP1_STRLI
Sequence: MAEELTPENPAIPETPEETEEPIKQRKNGLYPGVSDELAENMQSGWADTELHDLEPIAQAAETAARRAALSARFPGERLVIPAGNLKTRSNDTEYSFRASVEYAYLTGNQTEDGVLVMEPEGDGHAATIYLLPRSDRENGEFWLDGQGELWVGRRHSLAEAGELYGIPASDVRELAGSLREATGPVRVVRGFDAGIEAALTDKVTAERDEELRVFLSEARLVKDEFEIGELQKAVDSTVRGFEDVVKVLDRAEATSERYIEGTFFLRARVEGNDVGYGSICAAGPHACTLHWVRNDGPVRSGDLLLLDAGVETHTYYTADVTRTLPISGTYSELQKKIYDAVYDAQEAGIAAVRPGAKYRDFHDASQRVLAERLVEWGLVEGPVERVLELGLQRRWTLHGTGHMLGMDVHDCAAARVESYVDGTLEPGMVLTVEPGLYFQADDLTVPEEYRGIGVRIEDDILVTADGNRNLSAGLPRRSDEVEEWMAALKG
What are the official names of this protein?
Xaa-Pro aminopeptidase 1, Aminoacylproline aminopeptidase I, Aminopeptidase P I, APP, PEPP I, X-Pro aminopeptidase I, Xaa-Pro aminopeptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: H1L_MYTTR
Sequence: MPSPSRKSRSRSRSRSKSPKRSPAKKARKTPKKPRAAGGVKKPSTLSMIVAAITAMKNRKGSSVQAIRKYILANNKGINTSHLGSAMKLAFAKGLKSGVLVRPKTSAGASGATGSFRVGKAPASPKKAKKAKSPKKKSSKNKSNNAKAKKSPRKKAAVKKSTKSKAKKPKSPKKKAAKKTARKSPKKKARKSPKKKAAKKSKK
What is the function of this protein?
Linker histones are implicated in chromatin remodeling and/or transcriptional regulation during spermiogenesis, the process of spermatid maturation into spermatozoa.  Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex (By similarity).
What are the official names of this protein?
Sperm-specific protein PHI-2B/PHI-3.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: OBG_CUPMC
Sequence: MKFIDEARIEAIAGNGGNGSASFRREKFVPFGGPDGGDGGRGGSVFAQADRNINTLIDFRYAKKHVARNGENGRGSDCYGAAGEDVTLRMPVGTLISDMDTGEVIADLTEHGQLVCLAEGGMGGWGNLHFKSSTNRAPRQQVDGKPGERRMLKLELKVLADVGLLGMPNAGKSTFISHVSNARPKVADYPFTTLHPNLGVVRVDHEQSFVVADIPGLIEGAAEGAGLGHQFLRHLQRTGLLLHIVDIAPFDENVDPVAEAKAIVNELKKYDETLYDKPRWLVLNKLDVVPEEERAARVKDFVKRYKWKGPVFHISALTGEGCRELVYAIKDHLAALKAEEAAALAEPDIRLDDRLHNVDRDDSKA
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FYWP_LACLM
Sequence: MENSTGLKSSLKTRHIVMLSLGGAIGSGLFLGSGKVIAQAGPSVLLSYVLAGLTLYVVMYGVGKMVIHQDDHKAGMAGVVAPFIGDHWAHFADWVYWATWMAVLIAEEAGVSTFLAILIPGVPLWVFALVVAVLGTAINLWSVKAFAETEYWLAFIKVAVILLLIALGIYLLVINDAHLGFVADSAQKVTTKSTAPSFAPNGFSGFLTSLLVVIFSFGGSELAAITVAETENPKVAIPRAIRGVLIRIISFYVIPIFLFLHLLPWSEVSNPDAASPFATIFARVGIPHADKIVLVIIVIAIFSAVNSAIYATSRSLYSRIQGSSTYVGKKLGKLSKNQVPTNAILVSSFVLFIGVLLSAVLGDGFWQFVAGSISFTISIVWILLLVAALVLYFKHKEVTNWFVKLATLVVLIALSLVFIMQIITNPWTLSVFALVICLLSYFSYRKKKSIIEKTFIL
What is the function of this protein?
Involved in phenylalanine and tyrosine uptake.  Has also affinity for tryptophan.  Plays no significant role in the excretion of accumulated phenylalanine.
What are the official names of this protein?
Aromatic amino acid permease FywP.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CDD_SALTY
Sequence: MHPRFQTAFAQLADNLQSALAPILADHHFPAMLTAEQVSTLKNTAGLDEDALAFALLPLAAACARTDLSHFNVGAIARGVSGNWYFGANMEFLGATMQQTVHAEQSAISHAWLRGEKGLAAVTVNYTPCGHCRQFMNELNSGLDLRIHLPGRAPHTLRDYLPDAFGPKDLEIKTLLMDEQDHGFTLTGDTLTQAAITAANKSHMPYSHSPSGVALECKDGRIFTGSYAENAAFNPTLPPLQGALNLLSLNGYDYADIQRAILAEKGDAALIQWDATAATLKALGCHNIDRVLLG
What is the function of this protein?
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
What are the official names of this protein?
Cytidine deaminase, Cytidine aminohydrolase, CDA.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: YGI2_BACTU
Sequence: MKKLLISFIAILFFICGFNLKAFAAEEIIDYQSLYNQAIQEGVLDQNSVSYNEWLKQNKEEFMPIYQDGLKQGVFLEPLSYNEWLKLNNYGQAPTGDIELFDDVTPRGSWGGFTLKAGDIFITNATSSAGIVGHAAIANGDNYILHMPGAGQGNQQLSTSNWMQKYTASGKWIKVYRLKDQTLARDVARYADRNFYSTTGSATKNVYLDYGIDTHLYQKNPTYCSKLVFQALYFGSGSRNVMQAVSGIVTPYGLIDTFTSAYRPSLVKTY
What is the function of this protein?
Possibly involved in pGI2 replication mechanism.
What are the official names of this protein?
Uncharacterized 30.3 kDa protein, ORF 2.
Protein: GP135_HUMAN
Sequence: MEEPQPPRPPASMALLGSQHSGAPSAAGPPGGTSSAATAAVLSFSTVATAALGNLSDASGGGTAAAPGGGGLGGSGAAREAGAAVRRPLGPEAAPLLSHGAAVAAQALVLLLIFLLSSLGNCAVMGVIVKHRQLRTVTNAFILSLSLSDLLTALLCLPAAFLDLFTPPGGSAPAAAAGPWRGFCAASRFFSSCFGIVSTLSVALISLDRYCAIVRPPREKIGRRRALQLLAGAWLTALGFSLPWELLGAPRELAAAQSFHGCLYRTSPDPAQLGAAFSVGLVVACYLLPFLLMCFCHYHICKTVRLSDVRVRPVNTYARVLRFFSEVRTATTVLIMIVFVICCWGPYCFLVLLAAARQAQTMQAPSLLSVVAVWLTWANGAINPVIYAIRNPNISMLLGRNREEGYRTRNVDAFLPSQGPGLQARSRSRLRNRYANRLGACNRMSSSNPASGVAGDVAMWARKNPVVLFCREGPPEPVTAVTKQPKSEAGDTSL
What is the function of this protein?
Orphan receptor.  Has spontaneous activity for beta-arrestin recruitment (PubMed:28827538).  Shows a reciprocal regulatory interaction with the melatonin receptor MTNR1B most likely through receptor heteromerization (PubMed:28827538).
What are the official names of this protein?
G-protein coupled receptor 135.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Note=Colocalizes with ARRB2/beta-arrestin-2 in the endosome.
Protein: PUR9_BURVG
Sequence: MIKQALISVSDKTGIVDFAKSLSDLGVKLLSTGGTAKLLADAGLPVTEVADYTGFPEMLDGRVKTLHPKVHGGILARRDLPEHMQALEQHDIPTIDLLVVNLYPFVATIAKDDCTLADAIENIDIGGPTMLRSAAKNHRDVTVVVDPADYAVVLDEMKANGNAIGYATNFRLATKVFAHTAQYDGAITNYLTSLTDELQHASRSTYPATLNLAFDKVQDLRYGENPHQSAAFYRDLAAPAGALANYRQLQGKELSYNNIADSDAAWECVKTFDAPACVIIKHANPCGVAVGNDPADAYAKAFQTDPTSAFGGIIAFNREVDEAAAQAVAKQFVEVLIAPSFSAAAQQVFAAKQNVRLLEIALGDGHNAFDLKRVGGGLLVQSLDSRNVQPSELRVVTKRQPSAKEMDDLLFAWRVAKYVKSNAIVFCGNGMTLGVGAGQMSRVDSARIASIKAQNAGLTLAGSAVASDAFFPFRDGLDVVVAAGATCVIQPGGSMRDDEVIAAADEHGIAMVLTGVRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: YCGN_SALPB
Sequence: MADTLMSDTPFWQRKTLDEMTDAEWESLCDGCGQCCLHKLMDEDTDEIYFTNVACRQLKIKTCQCRHYERRFEFEPDCIKLTRENLPDFEWLPMTCAYRLLAEGKPLPTWHPLLTGSKAAMHGERISVRHIAVKESEVRDWQDHILNKPSWAE
What are the official names of this protein?
UPF0260 protein YcgN.
What is the protein family that this protein belongs to?
Belongs to the UPF0260 family.
Protein: PTH_SYNJB
Sequence: MTQVKPKEVDEISLQLVVGLGNPGPQYANTRHNCGFMVVDRLAQRWGIPLVLEKRFQGSYGEGFALGGKRRLLKPETYMNRSGQSVRAVLDWYKLDLASVLVVYDDMDLPLGRLRLRGSGSAGGHNGMKSIIQHLGSEAFPRLRLGVGKPKGSQDVVGHVLGGFAPAEQEVLERVLDVAVEAVECCWQEGLRTAMNRFNPLDLSGPSSDLDGSNPAPGHGEASS
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_NEIMB
Sequence: MARSLKKGPYVDLHLLKKVDAARASNDKRPIKTWSRRSTILPDFIGLTIAVHNGRTHVPVFISDNMVGHKLGEFSLTRTFKGHLADKKAKKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: GLMM_PSESM
Sequence: MTTRKYFGTDGIRGRVGQFPITPEFMLKLGWAAGMAFRKMGACRILVGKDTRISGYMFESALEAGLSAAGADVLLLGPMPTPAIAYLTRTFHAEAGIVISASHNPHYDNGIKFFSGQGTKLPDEIEMMIEELLDAPMTVAESENLGKVSRINDAAGRYIEFCKSSVPTSTDFAGLKVVIDCAHGATYKVAPNVFRELGAQVVVLSAQPDGLNINKDCGSTHMEALQAAVVAEHADMGIGFDGDGDRVLMVDHTGTIVDGDELLYIIARDLHERGRLQGGVVGTLMSNLGLELALAEQNIPFVRANVGDRYVIAELLERNWQIGGENSGHIVCFQHATTGDAIIASLQVILALRRSGISLAEARLKLRKCPQILINVRFEGSSVDPVTHPSVQEACARVTEQMAGRGRVLLRKSGTEPLVRVMVEGEDEAQVRAYAEELAKLVAEVCA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: ZNUC_AERHH
Sequence: MTQLVELKEVCLSFDGRSVLDKVSFTLNKGKITTLVGPNGAGKSTLSKLVLGLLTPDSGQITRSRDLRVGYVPQRLYLDPTLPLTVRRFLQLGKNGRLSIEEALNRVGAEDLLDNRMQKLSGGEMQRVLLARALLVKPELLVLDEPVQGVDINGQIELYALISQLAAEFNCAVLMVSHDLHLVMASTHEVICLNRHVCCHGEPESVARHPEFARLFGRPEQEVLAVYTHHHHCDGEHHHHEPQVPVIRLPSRNQ
What is the function of this protein?
Part of the ABC transporter complex ZnuABC involved in zinc import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Zinc import ATP-binding protein ZnuC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HISZ_BRUA4
Sequence: MAGSSSSGVFNSLRATLDMREAELVEIPLIQPADPFLDMAGEDLRRRIFLTENENGDSLCLRPEFTIPVCRNHIALNAATPKRYAYLGEVFRQHRDGAAEFLQAGIEDLGASDEAASDARSIADALSCVRAAAPEAELEIVLGDQSVFAGMLKALGLPQGWRKKLLRSFGDANSMEQVLAELTGAQRRDPLPETLAGLVAEGDESGLARMLEAEMLEAGISPSAGRSPAEIARRLIEKEDLAATRFPASALDLLKQFLETRVTLDSAAVTLRAFASEHALDLAAVLQKFEARSEAIANAGIATKDIIYDASFGRPLDYYTGLVYEIRAPGVEKEGVLAGGGRYDRLLTMLGASENIPGVGFSIWLDRLQMLVGEKK
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRPE_BACSU
Sequence: MAFQILLNVFLAFCWMFLSNSPSAAGFITGYILGMLSLFFFRRFFTRQFYLWKLISIIKLCFIFIKELYLANVSVMKSVLSPKLNIRPGIFAFKTELTKDWEITMLSLLITLTPGTLVMDISDDRTILYIHAMDIEDAEKAIFDIRESFEKAIQEVSR
What is the function of this protein?
Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B. subtilis.  Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB.  MrpA may be the actual Na(+)/H(+) antiporter, although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance.  MrpA is required for initiation of sporulation when external Na(+) concentration increases.  Also transports Li(+) but not K(+), Ca(2+) or Mg(2+).
What are the official names of this protein?
Na(+)/H(+) antiporter subunit E, Mrp complex subunit E, Multiple resistance and pH homeostasis protein E.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y4225_HAEIE
Sequence: MIQKLFLLVRSLVILSIMLSLGNLIAYYIPSGVPGSIWGLLLLFLGLTTRVIHLNWIYLGASLLIRFMAVLFVPVSVGIIKYSDLLIEQINILLVPNIVSTCVTLLVIGFLGHYLYQMQSFTHKRKKVIKRKRKSGKTSQLVC
What are the official names of this protein?
UPF0299 membrane protein CGSHiEE_04225.
What is the protein family that this protein belongs to?
Belongs to the UPF0299 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: COAX_FRAAA
Sequence: MLLAIDVGNTNTVVGVFDGDDLADSWRVRTDPHATADELVLLYRGLLGEHRITGVSICSTVPAALRELRRMVVRAFRDLPVVIVEPGTRTGVPILIDNPKEAGADRIMNTLAAHHLYGGPAIVVDFGTSTNLDVVSARGEFIGGVLAPGIEIALDALASRAAQLRKVELTPPRSVIGKSTVEALQSGMIYGVAGQVDGLVRRIRAELGAHATAIATGGLASLVVKESETLDRHEPHLTLIGLRLVFEKNI
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECG_AQUAE
Sequence: MYYALLTLFVIIAVVLIISTLLQKGRGDVGAAFGGGMGQSIFGVGGVETILTKATYWLGALFLVLALLLSVIPKEKGSVVEKSVQTEQSEGKGTTQESGK
What is the function of this protein?
Subunit of the protein translocation channel SecYEG.
What are the official names of this protein?
Protein-export membrane protein SecG.
What is the protein family that this protein belongs to?
Belongs to the SecG family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1631_ARCFU
Sequence: MDKKILSLRIVMDDEMETKFYEIKKELGLSSNAEVVRFLVNRFYKELVKKGGLAAVLLSNFANLVSTDWNIVESLGVFPIFG
What are the official names of this protein?
Uncharacterized protein AF_1631.
Protein: CTL2_HUMAN
Sequence: MGDERPHYYGKHGTPQKYDPTFKGPIYNRGCTDIICCVFLLLAIVGYVAVGIIAWTHGDPRKVIYPTDSRGEFCGQKGTKNENKPYLFYFNIVKCASPLVLLEFQCPTPQICVEKCPDRYLTYLNARSSRDFEYYKQFCVPGFKNNKGVAEVLQDGDCPAVLIPSKPLARRCFPAIHAYKGVLMVGNETTYEDGHGSRKNITDLVEGAKKANGVLEARQLAMRIFEDYTVSWYWIIIGLVIAMAMSLLFIILLRFLAGIMVWVMIIMVILVLGYGIFHCYMEYSRLRGEAGSDVSLVDLGFQTDFRVYLHLRQTWLAFMIILSILEVIIILLLIFLRKRILIAIALIKEASRAVGYVMCSLLYPLVTFFLLCLCIAYWASTAVFLSTSNEAVYKIFDDSPCPFTAKTCNPETFPSSNESRQCPNARCQFAFYGGESGYHRALLGLQIFNAFMFFWLANFVLALGQVTLAGAFASYYWALRKPDDLPAFPLFSAFGRALRYHTGSLAFGALILAIVQIIRVILEYLDQRLKAAENKFAKCLMTCLKCCFWCLEKFIKFLNRNAYIMIAIYGTNFCTSARNAFFLLMRNIIRVAVLDKVTDFLFLLGKLLIVGSVGILAFFFFTHRIRIVQDTAPPLNYYWVPILTVIVGSYLIAHGFFSVYGMCVDTLFLCFLEDLERNDGSAERPYFMSSTLKKLLNKTNKKAAES
What is the function of this protein?
Isoform 1, but not isoform 3, exhibits some choline transporter activity.
What are the official names of this protein?
Choline transporter-like protein 2, Solute carrier family 44 member 2.
What is the protein family that this protein belongs to?
Belongs to the CTL (choline transporter-like) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL23_LACDA
Sequence: MDARDIILRPVITEKSADLMDSKKYTFDVALTATKLQVRDAIEEIFDVKVKSVNIMNVRGKEKRVGRYTGKIARRRKAIVALTEDSNDIKIFKDENNE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.