PharMolix/UniProtQA huggingface dataset:
Protein: CAS2B_MOOTA
Sequence: MILIYDINTEDNDGKRRLVKIMKTSRKYLSHVQKSVFEGDITEGQISLLKKEIMAIVNMKKDFVIIYSLRDGVKLNREILTDTPDPTDNFL
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Functions as a ssRNA-specific endoribonuclease.  Involved in the integration of spacer DNA into the CRISPR cassette.
What are the official names of this protein?
CRISPR-associated endoribonuclease Cas2 2.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Protein: ENGB_EHRCR
Sequence: MKLKTIMSKCEFMIGATHIKSLPDFSIPEIAIAGRSNVGKSSLINAITNNKKNAKTSSKPGCTKQINFYLINKDFMVLVDLPGYGYSKADKTTINNYLCLMEYYLLNSRNLLKVILLIDAKVGFKEIDLDFINWLELHQIHYQLVLTKIDKIKKEMLDVNVNYIKNLNLDFIMYPIISTSSQCKQGIEELIYEIAQCIKK
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: CLPP_XANCB
Sequence: MSIVTKALNLVPMVVEQTSRGERAYDIYSRLLKERLIFLVGPIDDHMANVIVAQLLFLEADNPEKDISIYINSPGGVVTAGMAIYDTMQYIKPDVSTICVGQAASMGALLLASGAAGKRYALPNSRVMIHQPLGGFQGQATDIDIHAREILTLRSRLNEILAKHTGQSLETIARDTERDNFKSAVDAQAYGLVDQVLERRPEESIQPS
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS1_CUPPJ
Sequence: MSPAFNASPNQLTLALSKGRIFKETLPLLEAAGIRVMEDPETSRKLILPTSDPAVRVIIVRASDVPTYVQYGAADFGVAGKDVLMEHGMTGLYAPIDLNIARCRMSVAVPAGFDYANAVRQGARLSVATKYVQTAREHFAKKGVHVDLIKLYGSMELGPLVGLSDAIVDLVSTGGTLRANNLVEVEEIVQISSRLVVNQAALKLKRERLTPILDAFEKASAALA
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECF_STRPF
Sequence: MWIKELELKHYRNYDHLLASFSSGLNVFIGNNAQGKTNFLEAIYFLSLTRSHRTRADKELIHFDHSTVSLTGKIQRISGTVDLEINLSDKGRVTKINALKQAKLSDYIGTMMVVLFAPEDLQLVKGAPSLRRKFIDIDLGQIKPVYLFELSHYNHVLKQRNSYLKSAQQIDAAFLAVLDEQLASYGARVMEHRIDFINALEKEANTHHQAISNGLESLSLSYQSSVVFDKKTSIYQQFLHQLEKNHQKDFFRKNTSVGPHRDDLAFYINGMNANFASQGQHRSLILSLKMAEVSLMKALTGDNPILLLDDVMSELDNTRQTKLLETVIKENVQTFITTTSLDHLSQLPEGIRIFHVTKGTVQVDSDIH
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HESX1_MOUSE
Sequence: MSPSLREGAQLRESKPAPCSFSIESILGLDQKKDCTTSVRPHRPWTDTCGDSEKGGNPPLHAPDLPSETSFPCPVDHPRPEERAPKYENYFSASETRSLKRELSWYRGRRPRTAFTQNQVEVLENVFRVNCYPGIDIREDLAQKLNLEEDRIQIWFQNRRAKMKRSRRESQFLMAKKPFNPDLLK
What is the function of this protein?
Required for the normal development of the forebrain, eyes and other anterior structures such as the olfactory placodes and pituitary gland.  Possible transcriptional repressor.  Binds to the palindromic PIII sequence, 5'-AGCTTGAGTCTAATTGAATTAACTGTAC-3'.  HESX1 and PROP1 bind as heterodimers on this palindromic site, and, in vitro, HESX1 can antagonize PROP1 activation.
What are the official names of this protein?
Homeobox expressed in ES cells 1, Anterior-restricted homeobox protein, Homeobox protein ANF, Rathke pouch homeo box.
What is the protein family that this protein belongs to?
Belongs to the ANF homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MUTS_LEGPL
Sequence: MASSHTPMMQQYLRIKTDYPDMLLFYRMGDFYELFFDDAKRASQLLDLTLTHRGQSADKPIPMAGVPYHAVENYLARLLKKGESVAICEQIGDPATSKGPVERQVTRIITPGTVTDEALLDARKDNILLAIHTQKQKIGIAWVDLGGGRFHLQELTEEHQLNAELVRLQPAELLCKESTPLPSFCSNFAVKFRPGWEFDASNAHKLLCEQFSVTDLSAFGEQNYPTALIAAGALLAYLKTTQKQSLPHLTTLTLEQSEDYLQLDASTQRHLELFENIHGGGEHCLLSILDKTACAMGSRLLKRWLGKPLKQHAIIQTRQQAIKEIIFLQQDVSLHQLIKQCADVERIVSRIALKSARPRDLVSLLQTLILLPAIHDELQENKTLLINEIKKEISPLPLLQQLLETAIIDNPPMLIRDGGVIAPGFDEELDELRNLSSNAHETLVKLEQEEKNRTGLSTLKLGYNSVQGFYIELSKAQAQNAPPHFHRKQTLKNVERYITPELKLFEDKVLSAQSKALAREKWLYDNLLEEIQQYIPELSDLAKSLAQLDVLVTLTERAQSLNWNCPNLVPESGIMIQAGRHPVIEPLLQERFIANDLELKPNQNMLLITGPNMGGKSTYMRQTALIVLLAHIGSFVPADEVRLGPLDRIFTRIGASDDLSSGRSTFMVEMTETAQILRQATSQSLVLIDEIGRGTSTYDGMALAYASCAFLASTIKAYTLFSTHYLELTELPKDFSCIRNVHLQASIKTGQIVFLYRVEEGCANRSYGLEVAELAGIPKEVLKLAHEHLNQIQDTQSILVQTQIIKPPTSPILTELKKIDPDRLTAKEALDLIYKLKQLECVESIN
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: AC891_PENBR
Sequence: MFFTQPPHLVKAEELKQEPPKGTAYSVAIPGTEQPGRSRVYRAWNAQKELLTTLDPQVTTAHDMFESTANRQPKNHCLGWRPYNSTTKTWDPYQWLTYETVQKRRAAFGAGLVELHQKHNCHRPGQYGVGLWAQNRPEWQITDLACISQSLYSVSIYDVLAPDATEYIINHAELNCVVTSLPHIPTLLKLKSSLPNLKMIVSLDPLDGPEQNGHSKRALLESMAAGLDLAIYTIDQVEELGLASKRGYNAPSASDIVTINYTSGTTGPPKGVVLTHGNAVAATSCGLTTIGQARGDTMCSYLPLAHIYARLAEHTAFWGGARIGYFHGNIVELVDDLKLLKPTGFMSVPRLYSRFGTAIRAATVEQPGFKGALSRHIVAAKMANMKNPDPSKATIKHALYDRIWAKKVAAALGLERAKYMISGSAPLDPTLHNFLRVATGTDVVQGYGLTESYASATAQSTQDLSSGNCGRLAPCTEACLVSLPDMEYSVEDKPFPRGELLLRGNNMFREYYKNDDETSKAVTEDGWFRTGDVCTVDAQGRFIIIDRRKNVLKLAQGEYISPERLEGVILSELGYVAQAYVHGDSSETFLVGIFGVAPDLFAPYASKVLGKTIAPTDVEGLKEHLNDDKLRRAVLRDLERVAKKHKFAGYERVRNVSLKVDPFTVENNLLTPTLKLKRPPVVKMYRTLLDQLYGQANEEQSAPRAKL
What is the function of this protein?
Acyl-CoA ligase involved in the biosynthesis of mycophenolic acid (MPA), the first isolated antibiotic natural product in the world obtained from a culture of Penicillium brevicompactum in 1893 (PubMed:31209052).  The peroxisomal acyl-CoA ligase 891 converts the intermediate MFDHMP-3C into MFDHMP-3C-CoA which impairs its diffusion from the peroxisome (PubMed:31209052).  The first step of the pathway is the synthesis of 5-methylorsellinic acid (5MOA) by the cytosolic polyketide synthase mpaC.  5MOA is then converted to the phthalide compound 5,7-dihydroxy-4,6-dimethylphthalide (DHMP) by the endoplasmic reticulum-bound cytochrome P450 monooxygenase mpaDE.  MpaDE first catalyzes hydroxylation of 5-MOA to 4,6-dihydroxy-2-(hydroxymethyl)-3-methylbenzoic acid (DHMB).  MpaDE then acts as a lactone synthase that catalyzes the ring closure to convert DHMB into DHMP.  The next step is the prenylation of DHMP by the Golgi apparatus-associated prenyltransferase mpaA to yield farnesyl-DHMP (FDHMP).  The ER-bound oxygenase mpaB then mediates the oxidative cleavage the C19-C20 double bond in FDHMP to yield FDHMP-3C via a mycophenolic aldehyde intermediate.  The O-methyltransferase mpaG catalyzes the methylation of FDHMP-3C to yield MFDHMP-3C.  After the cytosolic methylation of FDHMP-3C, MFDHMP-3C enters into peroxisomes probably via free diffusion due to its low molecular weight.  Upon a peroxisomal CoA ligation reaction, catalyzed by a beta-oxidation component enzyme acyl-CoA ligase ACL891, MFDHMP-3C-CoA would then be restricted to peroxisomes for the following beta-oxidation pathway steps.  The peroxisomal beta-oxidation machinery than converts MFDHMP-3C-CoA into MPA_CoA, via a beta-oxidation chain-shortening process.  Finally mpaH acts as a peroxisomal acyl-CoA hydrolase with high substrate specificity toward MPA-CoA to release the final product MPA (PubMed:31209052) (Probable).
What are the official names of this protein?
Acyl-CoA ligase 891, peroxisomal, ACL891.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Peroxisome matrix.
Protein: PAT1_YEAST
Sequence: MSFFGLENSGNARDGPLDFEESYKGYGEHELEENDYLNDETFGDNVQVGTDFDFGNPHSSGSSGNAIGGNGVGATARSYVAATAEGISGPRTDGTAAAGPLDLKPMESLWSTAPPPAMAPSPQSTMAPAPAPQQMAPLQPILSMQDLERQQRQMQQQFMNFHAMGHPQGLPQGPPQQQFPMQPASGQPGPSQFAPPPPPPGVNVNMNQMPMGPVQVPVQASPSPIGMSNTPSPGPVVGATKMPLQSGRRSKRDLSPEEQRRLQIRHAKVEKILKYSGLMTPRDKDFITRYQLSQIVTEDPYNEDFYFQVYKIIQRGGITSESNKGLIARAYLEHSGHRLGGRYKRTDIALQRMQSQVEKAVTVAKERPSKLKDQQAAAGNSSQDNKQANTVLGKISSTLNSKNPRRQLQIPRQQPSDPDALKDVTDSLTNVDLASSGSSSTGSSAAAVASKQRRRSSYAFNNGNGATNLNKSGGKKFILELIETVYEEILDLEANLRNGQQTDSTAMWEALHIDDSSYDVNPFISMLSFDKGIKIMPRIFNFLDKQQKLKILQKIFNELSHLQIIILSSYKTTPKPTLTQLKKVDLFQMIILKIIVSFLSNNSNFIEIMGLLLQLIRNNNVSFLTTSKIGLNLITILISRAALIKQDSSRSNILSSPEISTWNEIYDKLFTSLESKIQLIFPPREYNDHIMRLQNDKFMDEAYIWQFLASLALSGKLNHQRIIIDEVRDEIFATINEAETLQKKEKELSVLPQRSQELDTELKSIIYNKEKLYQDLNLFLNVMGLVYRDGEISELK
What is the function of this protein?
Activator of decapping that functions as a general and active mechanism of translational repression and required for P-body formation.  First decay factor recruited to mRNA, at a time when the mRNA is still associated with translation factors.  Subsequently, PAT1 recruits the hepta-heterodimer LSM1-LSM7 complex to P-bodies.  In association with the LSM1-LSM7 complex, stabilizes the 3' terminus of mRNAs.  This association is also required for mosaic virus genomic RNA translation.  Modulates the rates of mRNA-decapping that occur following deadenylation.  Might be required for promoting the formation or the stabilization of the preinitiation translation complexes.  Required for 40S ribosomal subunit joining to capped and/or polyadenylated mRNA.  With other P-body components, enhances the formation of retrotransposition-competent Ty1 virus-like particles.  Necessary for accurate chromosome transmission during cell division.
What are the official names of this protein?
DNA topoisomerase 2-associated protein PAT1, Decapping activator and translational repressor PAT1, Topoisomerase II-associated protein PAT1, mRNA turnover protein 1.
What is the protein family that this protein belongs to?
Belongs to the PAT1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, P-body.
Protein: Y956_STRPD
Sequence: MYSIKCDDNKAMPRERLMRLGAESLSNQELLAILLRTGNKEKHVLELSSYLLSHLDSLADFKKMSLQELQHLAGIGKVKAIEIKAMIELVSRILATDKTLTDSVLTSVQVAEKMMAALGDKKQEHLVVLYLDNQNRIIEEKTIFIGTVRRSLAEPREILYYACKNMATSLIVIHNHPSGNIEPSSNDYCFTEKIKRSCEDLGIICLDHIIVSYKDYYSFREKSTLF
What are the official names of this protein?
UPF0758 protein MGAS10270_Spy0956.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: NDOR1_HUMAN
Sequence: MPSPQLLVLFGSQTGTAQDVSERLGREARRRRLGCRVQALDSYPVVNLINEPLVIFVCATTGQGDPPDNMKNFWRFIFRKNLPSTALCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQLGGSALLPVCLGDDQHELGPDAAVDPWLRDLWDRVLGLYPPPPGLTEIPPGVPLPSKFTLLFLQEAPSTGSEGQRVAHPGSQEPPSESKPFLAPMISNQRVTGPSHFQDVRLIEFDILGSGISFAAGDVVLIQPSNSAAHVQRFCQVLGLDPDQLFMLQPREPDVSSPTRLPQPCSMRHLVSHYLDIASVPRRSFFELLACLSLHELEREKLLEFSSAQGQEELFEYCNRPRRTILEVLCDFPHTAAAIPPDYLLDLIPVIRPRAFSIASSLLTHPSRLQILVAVVQFQTRLKEPRRGLCSSWLASLDPGQGPVRVPLWVRPGSLAFPETPDTPVIMVGPGTGVAPFRAAIQERVAQGQTGNFLFFGCRWRDQDFYWEAEWQELEKRDCLTLIPAFSREQEQKVYVQHRLRELGSLVWELLDRQGAYFYLAGNAKSMPADVSEALMSIFQEEGGLCSPDAAAYLARLQQTRRFQTETWA
What is the function of this protein?
NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery (PubMed:10625700, PubMed:28648056, PubMed:23596212, PubMed:20802492, PubMed:15900210).  Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of CIAPIN1, another key component of the CIA machinery (PubMed:28648056, PubMed:23596212, PubMed:20802492).  In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins (PubMed:23596212, PubMed:20802492).  It can also reduce the [2Fe-2S] cluster of CISD1 and activate this protein implicated in Fe/S cluster repair (PubMed:28648056).  In vitro can fully activate methionine synthase/MTR in the presence of soluble cytochrome b5/CYB5A (PubMed:12871938).
What are the official names of this protein?
NADPH-dependent diflavin oxidoreductase 1, NADPH-dependent FMN and FAD-containing oxidoreductase, Novel reductase 1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Protein: PYREL_HALMA
Sequence: MKNIDDLVDSASDLAQRGLSKGEIADELNVSRETASWLVERSGTGTEPDTSDDGGPHDIHVDWSAVGRDSNRLYHAGAAMADLLSKKGDDVDLTIGIEKAGAPLATTVARELETDLGTYAPTKHQWDDDESETSDGSFSRNFAQIRNRDCYVVDDTITSGKTMGETIDAIHEQGGNPVACVVLADKRGIGDIRGVPVYSLLQVIRVGSDGDS
What are the official names of this protein?
PyrE-like protein.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
Protein: HTPX_CERS4
Sequence: MGYVRTGILMAVMTALFLGVGALIGGQSGAIIALVIAAGMNLFTFWNSDRAVLSMHGAHEVDPRAAPDLYNMVRGLADRAGMPMPKLYLIETDQPNAFATGRNPENAAVAVTRGLLRALTPEEVAGVVAHELAHIRNRDTLLMTVTATFAGAISMLANFAFFFGGSSNEEGERPMGLVGTLALMFLAPLAAGLVQMAISRSREYEADRIGAEICGRPLWLASALGKIEGLAQRIDNVRAERNPATAHMFIVNPLHAMGHDRLFATHPNTANRIAALRAMAEGAPQASRIPRVAARRGPWS
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YQHA_SALCH
Sequence: MERFLENVMYASRWLLAPVYFGLSLALIALALKFFQEILHVLPNVFALAEADLILVLLSLVDMTLVGGLLVMVMFSGYENFVSQLDISAGKEKLNWLGKMDATSLKNKVAASIVAISSIHLLRVFMDAKNVPDNKLMWYVIIHLTFVLSAFVMGYLDRLTRHNH
What are the official names of this protein?
UPF0114 protein YqhA.
What is the protein family that this protein belongs to?
Belongs to the UPF0114 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYFA_STRA5
Sequence: MDLQKQLEELKISTQEKLKEMTGNHTKELQDLRVQVLGKKGSLTELLKGLKDLSNDLRPVVGKQVNEVRDILTKAFEEQAKVVEAAKIQAQLESESVDVTLPGRQMTLGHRHVLTQTSEEIEDIFLGMGFQVVDGFEVEKDYYNFERMNLPKDHPARDMQDTFYITEEILLRTHTSPVQARTMDQHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQIEGLVVGENISMGDLKGTLQLISQKMFGAERKIRLRPSYFPFTEPSVEVDVSCFKCGGKGCNVCKQTGWIEILGAGMVHPSVLEMSGIDSEKYSGFAFGLGQERIAMLRYGINDIRGFYQGDVRFTDQF
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XERC_ACTP7
Sequence: MINSQNTLYLQTKPYWDYLRIEKQASQHTLSNYQRQLLAVSDMLSQAGISTWQEVNSATVRWIIAQSNKQGLGAKSIALRLVALRQWFSYLIRQEKMSVNPAVGIKAPKASKRLPKNIDAEQIGQLLTSDSHEPSDLRDLAMMELMYSSGLRLSELQGLDLGDMDLAGREVRLLGKGNKERIVPIGSKALEALNRWLAVRNQFKPQDNAVFLNKRGGRLSHRSIQLVMQKWGEKQGLESHLHPHKLRHSFATHMLEASGDLRAVQELLGHSNLATTQIYTHLDFQHLAKIYDAAHPRAKRKKQDDD
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAS2C_SYNY3
Sequence: MFLYVIAYDIPDDRRRKKMADLLEGYGQRVQYSVFECTLSKSKFNELQKRLRKIYQSEEDSLRFYPLSGHTLTQVDIWGEPPLTKPPGSVIV
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Functions as a ssRNA-specific endoribonuclease.  Involved in the integration of spacer DNA into the CRISPR cassette.
What are the official names of this protein?
CRISPR-associated endoribonuclease Cas2 3.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Protein: RK16_ANGEV
Sequence: MLNPRRTRFRKQHRGRMRGISTRGNRICFGKFALQALEPTWITARQIEAGRRAITRYARRGGKLWIRIFPDKPITMRPAETRMGSGKGSPEYWVSVVKPGRILYEISGVSENVARAAMKIAAYKMPIRTQFITTIKMKESILDRKE
What are the official names of this protein?
50S ribosomal protein L16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CYSI_SALEP
Sequence: MSEKHPGPLVVEGKLSDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTTQWQAIDKFAADNTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVAITDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGLETFKAEVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDNNWHLTLFIENGRILDYPGRPLKTGLLEIAKIHQGEFRITANQNLIIASVPESQKAKIETLARDHGLMNAVSAQRENSMACVSFPTCPLAMAEAERFLPSFTDKVEAILEKHGIPDEHIVMRVTGCPNGCGRAMLAEIGLVGKAPGRYNLHLGGNRIGTRIPRMYQENITEPDILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDFWE
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: SR1B_PHYPO
Sequence: MQVRNILVALVVVCFAVSEAATQAPTSPPDSSASAEQVAQLLNAPSELDRLKLLKDNQFVFDFKNSKLGVTQSAGGKTVATSRTDFPAVIGHNIAMTVGFIEACGINLPHTHPRATEINFIAKGRFQAGFFLENQATFIGHILEEGMATVFPQGAIHFEINLECEPAMFVAAFNNEDPGVQTTASSFFGLPADVAAVSLNISSIQTVEDLAKYLPHNPAIAMKECMQRCGMTGSSESSESSEDSSCSD
What are the official names of this protein?
Spherulin-1B.
What is the protein family that this protein belongs to?
Belongs to the germin family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: ACYP_MYCTA
Sequence: MSAPDVRLTAWVHGWVQGVGFRWWTRCRALELGLTGYAANHADGRVLVVAQGPRAACQKLLQLLQGDTTPGRVAKVVADWSQSTEQITGFSER
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: RL20_CAMJR
Sequence: MARVKTGVVRRRRHKKVLKLARGFYSGRRKHFRKAKEQLERSLVYAYRDRRRKKRDFRRLWIVRINAACRLNDLSYSRFINGLKKAGIELDRKILADLAMNDAAAFAKIAEAAKKAL
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: GLN1B_CERSP
Sequence: MSKVADALKLMKDEEVEYVDIRFTDPRGKLQHVTLVADLVDEDFFEEGFMFDGSSIAGWKSIDQSDMKLIPDAGSVYIDPFYAEKTLCVHCNVVEPDTGEAYSRDPRGAAVKAEAYLKASGIGDVAYFGPEAEFFIFDDVRYSVTPAKVAYQIDADAGAWNTDSEYEMGNLAHRAGHKGGYFPVNPIDEAQDLRGEMLSTMKRMGMKVDKHHHEVATCQHELGLIFGGLTEQADNILKYKYVIHNVAGMHGKTVTFMPKPMKGDNGSGMHVNMSIWKEQALFAGDKYADLSQEALWFIGGILKQPSVNALTNPATNSYKRLIPGFEAPVLRAYSARNRSGCVRIPWTESPNAKRVEARFPDPSANPYLAFAALLMAGLDGIKNKIDPGPASDKDLYDLPPEELAAIPTVCGSLREALEELEKDHDFLLAGDVFTKDQLEGYMALKWEEVYAYEHTPHPVEYQMYYSC
What is the function of this protein?
Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
What are the official names of this protein?
Glutamine synthetase, GS, Glutamate--ammonia ligase, Glutamine synthetase I beta, GSI beta.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPPH_HALHL
Sequence: MVDSDGFRPNVGIIVANDDGRVLWARRAGEDAWQFPQGGVEANETPLEALYRELREEVGLGPADVAVLGATRRWLRYRLPRRMIRRRGSRCIGQKQIWFLLRLLADEQRVRVDRVARPEFDRWRWVDYWYPVEEVIFFKRQVYRQALQELSGYLQADDWAGTGTEGGPAAVIPPAARRRLR
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: TRPA_SYNP2
Sequence: MTSVSERFRSLKQAGQCALIPFITAGDPDLETTEQALKILDAAGADFIELGVPYSDPLADGPTIQAAATRALSRGVTLEQVLAIVQRVHGQLTAPIILFTYYNPIFYRGIDAFMAQVAAAGVKGLVIPDLPLEESQMVLDAATSHGLDLILLVAPTSPTERIEAIAKASQGFIYLVSVTGVTGARTSVASRVGELLPKLRQVTDKPIGVGFGVSDPAQARQLKEWGADGVIVGSAVVKRLATGTPAEGLAAVKEFCESLKEAIA
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: RL4_ACIF2
Sequence: MQVQSLEVTTGKSSEIEIADGVFGVPYNEALLHQVVVAQMAGMRSANAVQKNRAAVRGGGRKPWKQKGTGRARAGSIRSPIWRGGGRAFPGGNENYTQKVNKKMWAGAMRTVLAELLRQGRLQIIQQEDFGEPRSRLGRDWLSRAGGDNVLLVMGEVPLNLFLGLRNFPRVGIAGWQDVGPADLLQYGRVLLDVEAAARLGEVYG
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: MVP_CHICK
Sequence: MEDPVIRIPPYHYIHVLDLNSNVTRVEVGPHSFIRQDHERVVFSPKRMVMVPPRHYCVVLNPVARGPTGAVLFDGAGQAQLRHADLDIRLTQEPFPLYPGEELQQGVTPLQVVLADTALRLRALLDFEDEDGNKFVAGDEWLFEGPGTYIPHKEVEVVETLQATIIRHNQAIRLRARKECLDRQGTRRVTGEEWLVKRVGAYLPGVYEEVVDVVDAYVLTDKKALHLRATRTFEDVQGHVRRTGEEWLVTQEQSEAYVPDVFEEVVAEVLVTTLGPRQYCVVLDPVGPNGQPQLGQQRVVKGEKSFFLQPGERLQAGIQDVYVLSEDEGLLLQALQTIKDTDEDGTEVIRRAGDRWLARGPLEYVPPAEVTVLERRQALALAENEGIYVRDIRTGKVRVVTGQTYMLTESEELWEKELPPGVEVLLAEARGDTAGQDSGIQSSSGPSFGVQERDRTRAVTYQVPHNAAVQVYDYRERRARVVLGPELVVLGPGEQLTVLSLSGGRPKRPHARRSLCLRLGPDFCADIVTIETADHARLQLQLAYNWHFEVPEDPKALGRLFSVPDFVGDACKALASRVRGAVAAVTFDDFHKNSNRLICSAVFGFDEGGRLREHLRFVPNGLVVTSVDIQSVEPVDQRTRDALQRSVQLAIEIATNSQEAAARHEAERLAQEARVRLERQRLLDQAEAERARRELLELEALSAAVESAGAARAEAQARAEAARIEAEAAILQAKLKAEAVAIETEAELARLERMQAQEVRAQRARAEAEAARAQALAAVEASKVREVAAALGPETIRDIARAGPELQVKLLQGLGLQSALITDGAAPLNLFSTARGLLGLAVPPEPSTS
What is the function of this protein?
Required for normal vault structure.  Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction.  Vaults may also play a role in nucleo-cytoplasmic transport (By similarity).
What are the official names of this protein?
Major vault protein, MVP.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.