PharMolix/UniProtQA huggingface dataset:
Protein: SYI_EDWI9
Sequence: MSDYKNTLNLPETGFPMRGDLAKREPGMLQHWYEQDLYGIIRNAKQGKKSFILHDGPPYANGSIHIGHSVNKILKDIIIKSKGLSGYDSPYIPGWDCHGLPIELKVEQLIGKPGEKYSAAEFREQCRAYAAEQVAGQKADFIRLGVLGDWEHPYLTMDYGTEANIIRALARIVDNGHLMKGAKPVHWCPDCGSSLAEAEVEYYDKVSPSIDVRFAAVDKAQVLAKFGVSEAKGDVNVVIWTTTPWTLPANRAVALHPELEYQLVQVEGECLILAADLVESVMKRAGIDYWQVLGSCKGEALELLHFCHPFMNFDVPIIMGDHVTLDAGTGAVHTAPGHGPDDYVVGQKYGLEIANPVGSNGCYLPGTHPVLDGLFVFKANDIVIDLLKDSGALLHVEKLTHSYPCCWRHKSPIIFRATPQWFISMDRQGLRSQSLAEIDRIERQGLDEQNLSGWIPAWGKARIESMVANRPDWCISRQRTWGVPMAMLVHKETQELHPRTTELMEMVAKRVEQAGIQAWWDLDIRDLLGDEADQYEKVPDTLDVWFDSGSTSYSVVDARPEFNGHSPDMYLEGSDQHRGWFMSSLMISVAMKGKAPYRQVLTHGFTVDGQGRKMSKSVGNVVSPQQVMNKLGGDILRLWVASTDYTSEMAVSDEILKRSADAYRRIRNTARFLLANLNGFDPCKDMVKPEDMVVLDRWAVGCAKQAQDEIIAAYENYDFHEVVQRLMQFCSVEMGSFYLDIIKDRQYTAKADSVARRSCQTALYHIAEALVRWMAPILSFTADEVWGYLPGDRAQFVFTEEWYQGLFGLDAAEQMNDAFWAELLKVRGEVNRVIEQARNDKKVGGSLEAAITLYADEALATQLDSLQDELRFVLITSAARVQPLVQATADAVASELAGLKVGLGKADGSKCPRCWHYSTAIGQDAAHPQLCPRCVTNVAGQGEERKFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KLHL2_RAT
Sequence: MESPPLPPACTKQGHQKPLDSKDENPEKHCPLTVNPWHMKKAFKVMNELRSQNLLCDVTIVAEDMEIPAHRVVLAACSPYFHAMFTGEMSESRAKRVRIKEVDGWTLRMLIDYVYTAEIQVTEENVQVLLPAAGLLQLQDVKKTCCEFLESQLHPVNCLGIRAFADMHACTDLLNKANTYAEQHFADVVLSEEFLNLGIEQVCSLISSDKLTISSEEKVFEAVIAWVNHDKDVRQEFMARLMEHVRLPLLPREYLVQRVEEEALVKNSSACKDYLIEAMKYHLLPTEQRMLMKSVRTRLRTPMNLPKLMVVVGGQAPKAIRSVECYDFKEERWHQVAELPSRRCRAGMVYMAGLVFAVGGFNGSLRVRTVDSYDPVKDQWTSVANMRDRRSTLGAAVLNGLLYAVGGFDGSTGLSSVEAYNIKSNEWFHVAPMNTRRSSVGVGVVGGLLYAVGGYDGASRQCLSTVECYNATANEWTYIAEMSTRRSGAGVGVLNNLLYAVGGHDGPLVRKSVEVYDPTTNAWRQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCNLASVEYYNPTTDKWTVVSSCMSTGRSYAGVTVIDKPL
What is the function of this protein?
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, such as NPTXR, leading most often to their proteasomal degradation.  Responsible for degradative ubiquitination of the WNK kinases WNK1, WNK3 and WNK4 (By similarity).  Promotes growth of cell projections in oligodendrocyte precursors.  Plays a role in the reorganization of the actin cytoskeleton.
What are the official names of this protein?
Kelch-like protein 2, Mayven.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, ruffle. Cell projection. Cell projection, lamellipodium. Cytoplasm, cytosol. Note=When over-expressed, colocalizes with NPTXR in perinuclear aggresomes (By similarity). A proportion colocalizes with the actin cytoskeleton.
Protein: CHP2_SCHPO
Sequence: MVKSADLDLMNSIISESDENFSPPPFTVEEAENSINNKSSTASLESPQNGSWHPSLYGLSVPEKTHIQNSLDLYSHGNSGSQKTHNVSFSCEIRKVKSSKLSPISNMEDSEDKKEEDESSSYKNEFKSSSSASVSSNFEKTSGSDDHNSQSPVPLNEGFEYIASSGSEDKNSDEEFAVEMILDSRMKKDGSGFQYYLKWEGYDDPSDNTWNDEEDCAGCLELIDAYWESRGGKPDLSSLIRLTRSRARSSNEASYVEKDESSNSDDSISYKRRRSRNAANRITDYVDSDLSESSMKEKQSKIEKYMKSDKSSKNFKPPFQKKSWEDLVDCVKTVQQLDNGKLIAKIKWKNGYVSTHDNIIIHQKCPLKIIEYYEAHIKFT
What is the function of this protein?
Component of the kinetochore which plays a role in stabilizing microtubules and so allowing accurate chromosome segregation.
What are the official names of this protein?
Chromo domain-containing protein 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: FINO3_ECOLX
Sequence: MTEQKRPVLTLKRKTEGETPTRSRKTIINVTTPPKWKVKKQKLAEKAAREAELTAKKAQARQALSIYLNLPTLDEAVNTLKPWWPGLFDGDTPRLLACGIRDVLLEDVAQRNIPLSHKKLRRALKAITRSESYLCAMKAGACRYDTEGYVTEHISQEEEVYAAERLDKIRRQNRIKAELQAVLDEQ
What is the function of this protein?
One of the components on the FinOP fertility inhibition complex, which inhibits the expression of traJ gene, which in turn regulates the expression of some 20 transfer genes.  The transfer genes are responsible for the process, called conjugal transfer, in which DNA is transmitted from one bacterial host to another.  RNA-binding that interacts with the traJ mRNA and its antisense RNA, finP, stabilizing finP against endonucleolytic degradation and facilitating sense-antisense RNA recognition (By similarity).
What are the official names of this protein?
Fertility inhibition protein, Conjugal transfer repressor.
What is the protein family that this protein belongs to?
Belongs to the FinO family.
Protein: F16PC_PORG3
Sequence: MLKHDLDYLELLSESFPTATEVATEIINLEAILNLPKGTEHFLADIHGEYEAFIHVLKNASGSIRRKVDEVFGGQLRQNQKRELCTLIYYPREKLELVKQSDERMEDWYMVTLNQLIKVCQKAAEKYTRSKVRKTLPPKYSYIIQELLHEDGVNPNKSAYISSIFSSIISTGCADDFIIAISETIQRLVIDHLHVVGDVFDRGPGAHIIMDTLMKYHHFDIQWGNHDMLWMGAAVGNASCMANVVRIALRYANLDTLESGYGINLLPLARFAMDTYADDPCTVFKPKLAQADQTYDDKSVYLISQMHKAISIIQFKLEHQIIARHPEYKMDNRDLFHLVNFTDGTIKLSSGVYPMLDMNFPTVDPADPYALTEQEQNIVDRLMGCFMRSEKLQNHLKCLYRHGSMYLTYNMNLLYHASIPLNKDKSLKKVRVGDKTYAGRELLDKVEEMIRTAYVAPEKSDQRLAAVDYMWYLWCGPDSPLFDKAMMTTFERYFIEDKATHHEEKGYYYVYRQEKAVCEMILKEFGLEGPDTHIINGHVPVKAKKGELPIGAEGKLMLIDGGFSKAYQSSTGIAGYTLIFNSQGLHLVQHEPFSSTRKAIEEMEDIKSITVVREVTSHRMLVKDTDNGHLLSKQVENLKKLLQAYSYGLIKERKK
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 3, FBPase class 3, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 3 family.
Protein: IHFA_HISS2
Sequence: MALTKIELKNSLIEQGLNKLEAKKVVEGFFEQIRVSLENGEDVKLSGFGNFELRDKSSRPGRNPKTGEAIPVSARRVVVFRPGQKLRSRVEKTKPKN
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: RBIS_HUMAN
Sequence: MAKNKLRGPKSRNVFHIASQKNFKAKNKAKPVTTNLKKINIMNEEKVNRVNKAFVNVQKELAHFAKSISLEPLQKELIPQQRHESKPVNVDEATRLMALL
What is the function of this protein?
Trans-acting factor in ribosome biogenesis required for efficient 40S and 60S subunit production.
What are the official names of this protein?
Ribosomal biogenesis factor.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: HS30C_XENLA
Sequence: MFPLSLVQPSHSPLCPCSQPALTLWPATRLIFGHLEDDILSMRNDMERRMQRVNEACRLLSKDTEMRRITDQNRQSRESEGTSPNSGKDGKDHFELTLNVRDFSPHELTVKTQGRRVIVTGKHERKSDTEDGNYFHEYREWKREAELPESVNPEQVVCSLSKNGHLHIQAPRLALPPAPETPIPISMDTAPRDAQELPPDAQTSNAEGDQKVD
What are the official names of this protein?
Heat shock protein 30C.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
Protein: RLR93_PLAVT
Sequence: MRFYLTKLFAAAGALAWTTGLSTANAVTTPVSPLSRSSDHHQSDDSTQRRLRTLNGADEERMSPLTMTRLRAALAFELELVDFDSLAQNQFLARVREMLGIKVTGSTTAGLPKMIRRFGVKNSAKNVAKRVQDPAKQADLIAGLLIYPVKQRDLLGDELLRKWPYLTVSAIKKRVIAEKNRKVHKKPRPFAAHVHAPTIAAY
What is the function of this protein?
Secreted effector that completely suppresses the host cell death induced by cell death-inducing proteins.
What are the official names of this protein?
Secreted RxLR effector protein 93.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host nucleus.
Protein: RL17_HELPJ
Sequence: MRHKHGYRKLGRTSSHRKALLKNLAIALIEHNKIETGIYKAKELRSYIEKLTTVARVGDFNAHRHVFAYLQNKEATHKLVTEIAPKYAQRNGGYTRIQRTTFRRGDASTLATIEFV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: MED14_SCHPO
Sequence: MEPPAIPHITEGFYPLPEIVETFSHHVLQELVSLAEVLPSMSNVEKKKKILDWLLRSRAFTMRLLVLARWVHLSPSVHRCIDVVAFLQGQKFCFQNLVHVLQDIRYQLSFARLRNSDLVTALDILSTGTSLRLANAPTSKLYMLSESPLSTKQILQTLHALNMLIRIRLSLYEIIPTPFQHFTIANGRCTFTVPNEFSVSLTTNSQDPKSTGISFQWIVVDFQFHLPDFSSTPAKYRVFIELHLNEEIAAAFVLQKPILPLIYNILHKFCLYQRLNLLSQQTFQLSRESWLGHLRGVYDEKPPRLRLYYWPQLNVKKEGKPGKIGHYIHIFVNTQPISAFERTLSSKRSSCEYDHFLLLVEWHHDGIVEHVPLDDHMDAQHLLLLITQKHAQLILEQIRKELHPNIFSEHVGGGLKIHVFDNEIIVKVNSVTGRLVLSSSASPLSPPRHLRAAEKNIALNTQPPAQILNRLYFFCIQTQLLEVAQCAELHAVQGYYSFPYLTFSKGKWRKDGDSLWVLAYNVESNSWSVRLLNAAGQTLYTQDVHTTKGTLSIESFSRLSYLLEVQILLFNVQTACQARGMPFEYLPIPPKALIEDDFTTYVQTGCLCIMMPSSNEDMLPVVFVRAHDGQLIFDSRIKGKLPYQSETETEKNCYIDWRTGRITIRVQNFSSFEKTWIGLLKLVALSKTSAFNVDCITLKHVDFTYLDDEKFRATIHDDNTFTLHFFNRHSPFHLISQFLQDTFSDGPSAIQPLRVIMDRTRGVLVAQELGYVVLARSLRQYRIILSKNHGIQVLLNRHGCILQDLSYLSADSRYLEGTQTLTSQWEPCSWLNTVWEGDLGDDELNGQIEAAPEMHLIKMNKTADLTAILKRILAISRKK
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 14, Mediator complex subunit 14, Mediator of RNA polymerase II complex subunit pmc1.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 14 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PHSL_IPOBA
Sequence: MSRLSGITPRARDDRSQFQNPRLEIAVPDRTAGLQRTKRTLLVKCVLDETKQTIQHVVTEKNEGTLLDAASIASSIKYHAEFSPAFSPERFELPKAYFATAQSVRDALIVNWNATYDYYEKLNMKQAYYLSMEFLQGRALLNAIGNLELTGEYAEALNKLGHNLENVASKEPDAALGNGGLGRLASCFLDSLATLNYPAWGYGLRYKYGLFKQRITKDGQEEVAEDWLELGNPWEIIRMDVSYPVKFFGKVITGSDGKKHWIGGEDILAVAYDVPIPGYKTRTTISLRLWSTKVPSEDFDLYSFNAGEHTKACEAQANAEKICYILYPGDESIEGKILRLKQQYTLCSASLQDIIARFERRSGEYVKWEEFPEKVAVQMNDTHPTLCIPELIRILIDLKGLSWKEAWNITQRTVAYTNHTVLPEALEKWSYELMEKLLPRHIEIIEMIDEQLINEIVSEYGTSDLDMLEKKLNDMRILENFDIPSSIANLFTKPKETSIVDPSEEVEVSGKVVTESVEVSDKVVTESEKDELEEKDTELEKDEDPVPAPIPPKMVRMANLCVVGGHAVNGVAEIHSDIVKEDVFNDFYQLWPEKFQNKTNGVTPRRWIRFCNPALSNIITKWIGTEDWVLNTEKLAELRKFADNEDLQIEWRAAKRSNKVKVASFLKERTGYSVSPNAMFDIQVKRIHEYKRQLLNILGIVYRYKQMKEMSAREREAKFVPRVCIFGGKAFATYVQAKRIAKFITDVGATINHDPEIGDLLKVIFVPDYNVSAAELLIPASGLSQHISTAGMEASGQSNMKFAMNGCILIGTLDGANVEIRQEVGEENFFLFGAEAHEIAGLRKERAEGKFVPDERFEEVKEFIKRGVFGSNTYDELLGSLEGNEGFGRGDYFLVGKDFPSYIECQEKVDEAYRDQKIWTRMSILNTAGSYKFSSDRTIHEYAKDIWNIQPVVFP
What is the function of this protein?
Phosphorylase is an important allosteric enzyme in carbohydrate metabolism.  Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates.  However, all known phosphorylases share catalytic and structural properties.
What are the official names of this protein?
Alpha-1,4 glucan phosphorylase L isozyme, chloroplastic/amyloplastic, Starch phosphorylase L.
What is the protein family that this protein belongs to?
Belongs to the glycogen phosphorylase family.
What are the subcellular locations of this protein?
Plastid, chloroplast. Plastid, amyloplast.
Protein: NUOD_CERS5
Sequence: MDTKFDDVLTGEQKLRNFNINFGPQHPAAHGVLRLVLELDGEVVERCDPHIGLLHRGTEKLMETRTYLQNLPYFDRLDYVAPMNQEHAWCLAIERLTGVQVPRRASLIRVLYSEIGRVLNHLLNVTTQAMDVGALTPPLWGFEEREKLMVFYERASGARLHAAYFRPGGVHQDLTPRLIEDIEEWAEHFPKVLDDLDGLLTENRIFKQRNVDIGVVTEKDILDWGFSGVMVRGSGLAWDLRRSQPYECYDEFDFQIPVGKNGDCYDRYLCRMEEMRQSTRIIQQCLAKLRVEKGDVLARGKITPPPRAEMKTSMEALIHHFKLYTEGFHVPAGEVYAAVEAPKGEFGVYLVADGTNRPYRAKIRAPGFLHLQAIDYIAKGHLLADVSAIIGTLDVVFGEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TLP2_ARATH
Sequence: MSLKSILRDLKEVRDGLGGISKRSWSKSSHIAPDQTTPPLDNIPQSPWASLPPELLHDIIWRVEESETAWPARAAVVSCASVCKSWRGITMEIVRIPEQCGKLTFPISLKQPGPRDSPIQCFIKRNRATATYILYYGLMPSETENDKLLLAARRIRRATCTDFIISLSAKNFSRSSSTYVGKLRSGFLGTKFTIYDNQTASSTAQAQPNRRLHPKQAAPKLPTNSSTVGNITYELNVLRTRGPRRMHCAMDSIPLSSVIAEPSVVQGIEEEVSSSPSPKGETITTDKEIPDNSPSLRDQPLVLKNKSPRWHEQLQCWCLNFKGRVTVASVKNFQLVAEIDASLDAPPEEHERVILQFGKIGKDIFTMDYRYPLSAFQAFAICISSFDTKPACEG
What are the official names of this protein?
Tubby-like F-box protein 2, AtTLP2.
What is the protein family that this protein belongs to?
Belongs to the TUB family.
Protein: FABZ_SYNY3
Sequence: MSTPEVTPTLSDSNGNEAGVQTQFTIQEISDLLPHRYPFALVDRIIDFQPGKCAVGLKNVTINEPFFPGHIPDRPIMPGVLIVESMAQVGGVILTQLPGMRGKFFAFAGIDGVRFRRPVVPGDQLIMTVELQSFKLQRIAKMQGEARVDGQLVCGGEMLFSLID
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SP5G_BORT9
Sequence: MNITDVRIRRVDNKNPGSKLLAYVTVTFDDCLVLHNIRVIRGQKGVFIVMPNRRTKVGEYKDIVHPINQNFREILQSAIFKEYVKENPSSLELELG
What is the function of this protein?
Could be involved in septation.
What are the official names of this protein?
Putative septation protein SpoVG.
What is the protein family that this protein belongs to?
Belongs to the SpoVG family.
Protein: PTX2_PTEMU
Sequence: YCQEFLWTCDEERKCCGDMVCRLWCKKRL
What is the function of this protein?
Spider venom neurotoxin that blocks voltage-gated sodium channel Nav1. 3/SCN3A in human (IC(50)=1 uM) and rat (IC(50)=1 uM).  Partially inhibits human Kv11. 1/KCNH2/ERG (40% at 10 uM).
What are the official names of this protein?
Beta/kappa-theraphotoxin-Pm2a, Beta/kappa-TRTX-Pm2a, Pterinotoxin-2.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 30 (phrixotoxin) family.
What are the subcellular locations of this protein?
Secreted.
Protein: GOX_PENAG
Sequence: YLPAQQIDVQSSLLSDPSKVAGKTYDYIIAGGGLTGLTVAAKLTENPKIKVLVIEKGFYESNDGAIIEDPNAYGQIFGTTVDQNYLTVPLINNRTNNIKAGKGLGGSTLINGDSWTRPDKVQIDSWEKVFGMEGWNWDNMFEYMKKAEAARTPTAAQLAAGHSFNATCHGTNGTVQSGARDNGQPWSPIMKALMNTVSALGVPVQQDFLCGHPRGVSMIMNNLDENQVRVDAARAWLLPNYQRSNLEILTGQMVGKVLFKQTASGPQAVGVNFGTNKAVNFDVFAKHEVLLAAGSAISPLILEYSGIGLKSVLDQANVTQLLDLPVGINMQDQTTTTVSSRASSAGAGQGQAVFFANFTETFGDYAPQARDLLNTKLDQWAEETVARGGFHNVTALKVQYENYRNWLLDEDVAFAELFMDTEGKINFDLWDLIPFTRGSVHILSSDPYLWQFANDPKFFLNEFDLLGQAAASKLARDLTSQGAMKEYFAGETLPGYNLVQNATLSQWSDYVLQNFRPNWHAVSSCSMMSRELGGVVDATAKVYGTQGLRVIDGSIPPTQVSSHVMTIFYGMALKVADAILDDYAKSA
What are the official names of this protein?
Glucose oxidase, Beta-D-glucose:oxygen 1-oxido-reductase, Glucose oxyhydrase, GOD.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
What are the subcellular locations of this protein?
Secreted.
Protein: PCEA_DESHY
Sequence: MGEINRRNFLKVSILGAAAAAVASASAVKGMVSPLVADAADIVAPITETSEFPYKVDAKYQRYNSLKNFFEKTFDPEANKTPIKFHYDDVSKITGKKDTGKDLPTLNAERLGIKGRPATHTETSILFHTQHLGAMLTQRHNETGWTGLDEALNAGAWAVEFDYSGFNATGGGPGSVIPLYPINPMTNEIANEPVMVPGLYNWDNIDVESVRQQGQQWKFESKEEASKIVKKATRLLGADLVGIAPYDERWTYSTWGRKIYKPCKMPNGRTKYLPWDLPKMLSGGGVEVFGHAKFEPDWEKYAGFKPKSVIVFVLEEDYEAIRTSPSVISSATVGKSYSNMAEVAYKIAVFLRKLGYYAAPCGNDTGISVPMAVQAGLGEAGRNGLLITQKFGPRHRIAKVYTDLELAPDKPRKFGVREFCRLCKKCADACPAQAISHEKDPKVLQPEDCEVAENPYTEKWHLDSNRCGSFWAYNGSPCSNCVAVCSWNKVETWNHDVARVATQIPLLQDAARKFDEWFGYNGPVNPDERLESGYVQNMVKDFWNNPESIKQ
What is the function of this protein?
Catalyzes the reductive dechlorination of tetrachloroethene (PCE) to trichloroethene (TCE) and of trichloroethene to cis-1,2-dichloroethene (DCE) (PubMed:12057934, PubMed:24814779).  Can also use various chlorinated ethanes such as tetrachloroethane, pentachloroethane and hexachloroethane (PubMed:12057934).  Reduced methyl viologen can act as the artificial electron donor (PubMed:12057934).
What are the official names of this protein?
Tetrachloroethene reductive dehalogenase, PceA reductive dehalogenase.
What is the protein family that this protein belongs to?
Belongs to the PceA family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Secreted. Note=In the presence of PCE, the PceA cofactor-free precursor is formed and localizes in the cytoplasm (PubMed:22961902). After incorporation of the corrinoid cofactor and assembly and incorporation of the iron- sulfur clusters, the precursor protein is correctly folded and probably exported to the exoplasm via the TAT system (PubMed:22961902). In the absence of PCE, PceA is detected in large aggregates localized in the cytoplasm (PubMed:22961902).
Protein: CSEP4_BLUG1
Sequence: MRPFQLLSALAIFINLEAVEAAAYWDCDGTEIPERNVRAAVVLAFNYRKESFHGYPATFIIGSTFSGVGEVRQFPVEDSDANWQGGAVKYYILTNKRGSYLEVFSSVGSGNKCTFVEG
What is the function of this protein?
Secreted effector that increases susceptibility to infection in both monocotyledonous and dicotyledonous plants (PubMed:23441578, PubMed:30856238).  Non-catalytic homolog of fungal RNases that binds host RNA and inhibits the degradation of host ribosomal RNA induced by ribosome-inactivating proteins (RIPs), preventing host cell death, an inviable interaction and demise of the fungus (PubMed:30856238).
What are the official names of this protein?
Secreted effector CSEP0064.
What are the subcellular locations of this protein?
Secreted. Host cell.
Protein: RHG31_MOUSE
Sequence: MKNKGAKQKLKRKGAASAFGCDLTEYLESSGQDVPYVLKSCAEFIETHGIVDGIYRLSGITSNIQRLRQEFGSDQCPDLTREVYLQDIHCVGSLCKLYFRELPNPLLTYELYEKFTEAVSHRPEEGQLARIQNVILELPPPHYRTLEYLIRHLAHIASFSSKTNMHARNLALVWAPNLLRSKKIEATICNGDAAFLAVRVQQVVIEFILNHADQIFNGGAPGALQQDESRTITKSLTLPALSLPMKLVSLEEAQARSLATNHPARKERRENSLPEIVPPPFHTVLELPDNKRKLSSKSKKWKSIFNLGRSGSDSKSKLSRNGSVFVRGQRLSVEKATIRPAKSMDSLCSVPVEGKENKGNFSRTVTTGGFFIPATKMHASSTGSSCDLSKEGEWGQEGMPAGAEGGCEVGGQIRPLPEQLKVFRPIGDPESEQSAPKLLGMFYTSSDSPGKSVFTSSLFQMEPSPRHQRKALNISEPFAVSVPLRVSAVISTNSTPCRTPPKELQSLSSLEEFSFQGSESGGWPEEEKPLGAESFPGSVTKKAATEDTKPEPEVPGRAECSQSPPLDPGTQVEKKTLHVSLGSQVSKEAEKRPKAEKVMEESQGASQPKPSTPQESLGAGTEPLILHEMDEEDLAQALIWPEIQQELKIIESEEEFSSLPPAAQKTSPIPESSPAPFPFPEAPGSLPSSSAPREVWTRDAANQSIQEAAILTDREKLEPVCSLLESESQQELSPDPASLAPLEMLLFEKVSSPARIEIGGPRNLSPPLTPAPPPPTPLEEEPEVLLSKEGPDREDAARDSRTDVYTEQPTPKESPGIPTPCQREEAIASPNEKQNARHAVPENKGPGLPSPTKEVDIIPQEEGGAPHSAQEPSDCDEDDTVTDPAQHGLEMVEPWEEPQWVTSPLHSPTLKEVQESQTQGSQGHRLERRLCHRPSLRQSHSLDSKTTGNSHWTLEAPFSSSCANLETERNYEPLQPPAARTKIAGLEEKALKAFREFSGLKGLEVLPSQKGPSGIQPKPVETNFMGLAEGKEQEPQLELSNRQMKHSDVPGPDSSKESSPRAQDSTLPGEHPLQLQLKNTECGPSKGKHRPSSLNLDSATPIADLFRLENGAPFSSPGIELSELGDTKVTWMSSSHCKAAPWNSQDTQDLDIVAHTLTGRRNSAPVSVSAVRTSFMVKMCQAKAVPVIPPKIQYTQIPQPLPSQSTGEGGAQPLERSQEEPGSTPEIPQKSTKDDSPSSLGSPEEEQPKQETGASASRRQASITSCMYEGSSCSPEPSASTLASTQDAVVQCRKRTSETEPSGDNLLSSKLERASGGPKAFHRSRPGRPQSLILFPIMDHLPSSPTVIDSKVLLSPIRSPTQTVSPGLLCGELAENTWITPEGVTLRNKMTIPKNGQRLETSTSCFYQPQRRSVILDGRSGRQIE
What is the function of this protein?
Functions as a GTPase-activating protein (GAP) for RAC1 and CDC42.  Required for cell spreading, polarized lamellipodia formation and cell migration.
What are the official names of this protein?
Rho GTPase-activating protein 31, Cdc42 GTPase-activating protein.
What are the subcellular locations of this protein?
Cell projection, lamellipodium. Cell junction, focal adhesion.
Protein: MBL_DROME
Sequence: MANVVNMNSLLNGKDSRWLQLEVCREFQRNKCSRQDTECKFAHPPANVEVQNGKVTACYDSIKGRCNRDKPPCKYFHPPQHLKDQLLINGRNHLALKNALMQQMGIAPGQPVISGQVPAVATNPYLTGIPANSYSPYYTTGHLVPALLGPDPVTSQLGPVVPQTVQVAQQKIPRSDRLETSPLAAHHHQQQQQLQHQLNNINNNNNHSTAGAAATSTTATTTTNNAAAAAAAAAAAAAAAVMGHHTLEVGKKRAADTTDMFPLVFFCSFPSPCVFAFLNCSIFGFLRLWFSLFNLRH
What is the function of this protein?
Required for terminal differentiation of photoreceptor cells.  Vital for embryonic development.
What are the official names of this protein?
Protein muscleblind, Protein mindmelt.
What is the protein family that this protein belongs to?
Belongs to the muscleblind family.
Protein: RL14_TREPA
Sequence: MIQVQSRLNVADNSGARLVQCIKVVGGSRRRYASVGDIIVVAVKDALPTSVIKKGSVEKAVIVRVSKEYRRVDGTYIRFDDNACVVIDANGNPKGKRIFGPVARELRDMDFTKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: ECTC_VIBPA
Sequence: MIVRTLDECRNSERRVVADNWESVRMLLKDDNMGFSFHITTIYEGTETHIHYQNHLESVFCMSGEGEIEVVGGETYPIKPGTLYILDKHDEHYLRAYKNKEMVMACVFNPPITGAEVHDENGVYPLVD
What is the function of this protein?
Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.
What are the official names of this protein?
L-ectoine synthase, N-acetyldiaminobutyrate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the ectoine synthase family.
Protein: GRCA_ECOLI
Sequence: MITGIQITKAANDDLLNSFWLLDSEKGEARCIVAKAGYAEDEVVAVSKLGDIEYREVPVEVKPEVRVEGGQHLNVNVLRRETLEDAVKHPEKYPQLTIRVSGYAVRFNSLTPEQQRDVIARTFTESL
What is the function of this protein?
Acts as a radical domain for damaged PFL and possibly other radical proteins.
What are the official names of this protein?
Autonomous glycyl radical cofactor.
Protein: MRAZ_STAAC
Sequence: MFMGEYDHQLDTKGRMIIPSKFRYDLNERFIITRGLDKCLFGYTLDEWQQIEEKMKTLPMTKKDARKFMRMFFSGAVEVELDKQGRINIPQNLRKYANLTKECTVIGVSNRIEIWDRETWNDFYEESEESFEDIAEDLIDFDF
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: DAD1_CITUN
Sequence: MARSTGKDAQALFHSLRSAYAATPTTLKIIDLYVGFAVFTALIQVVYMAIVGSFPFNSFLSGVLSCVGTAVLAVCLRIQVNKDNKEFKDLPPERAFADFVLCNLVLHLVIMNFLG
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1, Oligosaccharyl transferase subunit DAD1, CitDAD-1-1, Defender against cell death 1, DAD-1.
What is the protein family that this protein belongs to?
Belongs to the DAD/OST2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.