PharMolix/UniProtQA huggingface dataset:
Protein: RM02_ORYSI
Sequence: MRQSIKGRALRHFTLSTGKSAGRNSSGRITVFHRGGGSKRLQRKIDLKRSTSSIGIVERIEYDPNRSSRIALVRWIEGVLPGRQRKFKTIEEFALPRKILESTTATIFCLFSFSSLSSPLAQGETASLSFGSSLGFPRIAVAGAKPAFFAERMREKKIGKKTFSLCEIRKWRTHCVLWAHRIKRKAALSWQSLRQQKTLELVGAAEHNESKLKADQGSLLPRQVLAYALCSGRPSYLHASRSFYKALLPVEASRFGSLPAKPPIGEGPKDGAYKVDRAPVTYILASHQLEAGNMVINCDCSKPSKSGFLRPAQNAHTYLRFQELGRTVNKGRVEGGSQLAASWPRPPAYRHEILDLNSKVGNSIPLADIRMGTWVHDIECHPGQGAKLARAAGTYAKIIKEPASQCLVRLPSGVEKLIDSRCRATIGIVSNPNHGARKLRKAGQSRWSGRRPIVRGVAMNPVDHPHGGGEGRTKGGRPSVSPWGKPTKAGFRAGVGVGKRRI
What are the official names of this protein?
60S ribosomal protein L2, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: H2A1_BOVIN
Sequence: MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHHKAKGK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A type 1, H2A.1b.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: FGFR_HALRO
Sequence: MKEFEVKVASTAFVLVLFSLTINQILASETSTKFRSPVPAPTVPDWNHLPNEGNEENVVSAPKQDGASGGQKPYWTKREKMMKRLHAEPAGNTVRFRCAVDGNPKPQVLWYKNDLIVQKNDRVGGYKYRNQVLILESVVLSDKGNYMCVARNEYGSINHTYQLDVQERSASKPILAEGLPQNKSAYIGDDVTFKCKVYSDAHPHIQWLKSINNHNNAAPNYTVLKAAGVNTTDLDMEVLILKNVSFEEAGEYTCLAGNSIGISHQSAWLSVLPVPPPTTDTITKGIPNETNIIIYVMCGVLVILFGLAVVLVLYYHCYNGKDPPMLVRIENPDNIPPMTKIEHPTMLFGNTQAWQRMCMPMQEPFEFNIQLDLQWELQREDITLVERLDEGFFGQVFKADLVTCNNTRKEKMVCAVKMLKGNRNEKDVLDLLTEMDQMKRVGKHKNIINLLGVCTQNGPLWLVIEYAAQGNLRDYLRRNRPQNTLCNLVLPSEGRNPDDELPVPHGDTLTQKDIVSFAFQVARGLEFLAQKKCIHRDLAARNVLVTEELVMKIADFGLARDIRSCDYYRKHTRGHLPYKWMALEAMSDNIFTHATDVWSFGVLLWEIFSLAGSPYPGIKTHELVKFLRSGERLDKPQYASQEMYRLMRDCWEEDPSKRPNFRTLVEDLDRMLAESSTEVYIDFAAGCEAEYSESSEDESESQNSDEEDDDSVFERMRQIDSLSNGNIPFNEEDSSNSDPYVAPLLQNEENVLQNEHARLRSEA
What is the function of this protein?
Receptor for basic fibroblast growth factor.
What are the official names of this protein?
Fibroblast growth factor receptor, HrFGFR.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: COAX_CLOTE
Sequence: MILVLDAGNTNMVLGLYEDKNLIADWRLSTDPLRTADEYSIQVIQLFLQSNLRLEDVEGVIVSSVVPNIMYSVEHMVAKYFKKKPIIVGPGTKTGINIKYDNPKEVGADRIVNAVAAHEIYKKPLVIIDFGTATTFCAVTQSGDYLGGAIAPGVKISSEALFEKAAKLPRVELMKPSSVICKNTVSSMQAGMTYGYGGLVDHIVSKIKQELMDSGEKEPLVVATGGLAKLISEESETIDIIHPFLTLEGLRIIYEKNKDLDA
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y133_RICCN
Sequence: MNLKDQEQTKIVNNLIAKTDYLLSNNLNPLESVRSEINKTLALTHSTYQQDSNIKKSWIQKSVQKIKDLFINIFSSNKTKNEPKLNLTSDKILKKYKY
What are the official names of this protein?
Uncharacterized protein RC0133.
Protein: NPY5R_HUMAN
Sequence: MDLELDEYYNKTLATENNTAATRNSDFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNLLILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSLVELQETFGSALLSSRYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGLSNKENRLEENEMINLTLHPSKKSGPQVKLSGSHKWSYSFIKKHRRRYSKKTACVLPAPERPSQENHSRILPENFGSVRSQLSSSSKFIPGVPTCFEIKPEENSDVHELRVKRSVTRIKKRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKADLVSLIHCLHM
What is the function of this protein?
Receptor for neuropeptide Y and peptide YY.  The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.  Seems to be associated with food intake.  Could be involved in feeding disorders.
What are the official names of this protein?
Neuropeptide Y receptor type 5, NPY5-R, NPY-Y5 receptor, NPYY5-R, Y5 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LWA_ANTEL
Sequence: MALKCHLVLLAITLLLAQCSGSVDKKDSTTNHLDEKKTDSTEAHIVQETDALKENSYLGAEEESKEEDKKRSAAPQQPGLWGKRQKIGLWGRSADAGQPGLWGKRQSPGLWGRSADAGQPGLWGKRQNPGLWGRSADAGQPGLWGKRQNPGLWGRSADAGQPGLWGKRQNPGLWGRSADARQPGLWGKREIYALWGGKRQNPGLWGRSADPGQPGLWGKRELVGLWGGKRQNPGLWGRSAEAGQPGLWGKRQKIGLWGRSADPLQPGLWGKRQNPGLWGRSADPQQPGLWGKRQNPGLWGRSADPQQPGLWGKRQNPGLWGRSADPQQPGLWGKRQNPGLWGRSADPQQPGLWGKSPGLWGRSADPQQPGLWGKRQNPGFWGRSADPQQPGLWGKRQNPGLWGRSADPQQPGLWGKRQNPGLWGRSADPQQPGLWGKRQNPGLWGRSADPQQPGLWGKRQNPGLWGRSAGSGQLGLWGKRQSRIGLWGRSAEPPQFEDLEDLKKKSAIPQPKGQ
What is the function of this protein?
Metamorphosin A may be part of an internal signaling system involved in control of metamorphosis.
What are the official names of this protein?
LWamide neuropeptides.
What is the protein family that this protein belongs to?
Belongs to the LWamide neuropeptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: AMYA1_ASPOR
Sequence: MMVAWWSLFLYGLQVAAPALAATPADWRSQSIYFLLTDRFARTDGSTTATCNTADQKYCGGTWQGIIDKLDYIQGMGFTAIWITPVTAQLPQTTAYGDAYHGYWQQDIYSLNENYGTADDLKALSSALHERGMYLMVDVVANHMGYDGAGSSVDYSVFKPFSSQDYFHPFCFIQNYEDQTQVEDCWLGDNTVSLPDLDTTKDVVKNEWYDWVGSLVSNYSIDGLRIDTVKHVQKDFWPGYNKAAGVYCIGEVLDGDPAYTCPYQNVMDGVLNYPIYYPLLNAFKSTSGSMDDLYNMINTVKSDCPDSTLLGTFVENHDNPRFASYTNDIALAKNVAAFIILNDGIPIIYAGQEQHYAGGNDPANREATWLSGYPTDSELYKLIASANAIRNYAISKDTGFVTYKNWPIYKDDTTIAMRKGTDGSQIVTILSNKGASGDSYTLSLSGAGYTAGQQLTEVIGCTTVTVGSDGNVPVPMAGGLPRVLYPTEKLAGSKICSSS
What are the official names of this protein?
Alpha-amylase A type-1/2, 1,4-alpha-D-glucan glucanohydrolase, Taka-amylase A, TAA.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPF_BURCH
Sequence: MNLNATLFAQMVVFLVLAWFTMKFVWPPLINALDERSKKIADGLAAAEKGKAELDAAHKRVDQELAQARNDGQQRIADAEKRAQAVAEEIKANAQAEAARIVAQAKAEAEQQIVKAREALRGEVAALAVKGAEQILKREVDQTAHAQLLNQLKAEL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: TRMY_NATPD
Sequence: MRQFIVIGHDVPTDPDAVSLADLPGAGRLDVLCRCLNSAFFLSHDLRDNVRVWLVVGDEYAIRFEGSELRRLNPDERSTAALVRGALAAREKAIGSMAANPSPGVYIRTQSLSGLLESVADDGPLVTLHEDGQPVVDIDPSAEPTFVLSDHHSFDDAETALLAAHADRRVSLGPEPLHADHAITVAHNYLDTDGYNRY
What is the function of this protein?
Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs.
What are the official names of this protein?
tRNA (pseudouridine(54)-N(1))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. TrmY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LHPL6_RAT
Sequence: MASSLTCTGVIWALLSFLSAATSCVGFFMPYWLWGSQLGKPVSFGTFRRCSYPVHDESRQMMVMVEECGRYASFQGIPSTEWRICTIVTGLGCGLLLLVALTALMGCCVSELISRTVGRVAGGIQFLGGLLIGAGCALYPLGWDSEEVRQTCGYISDQFDLGKCEIGWAYYCTGAGAAAAMLLCTWLACFSGKKQKHYPY
What are the official names of this protein?
LHFPL tetraspan subfamily member 6 protein, Lipoma HMGIC fusion partner.
What is the protein family that this protein belongs to?
Belongs to the LHFP family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NDK_DELAS
Sequence: MAIERTLSIIKPDAVAKNVIGQIYARFEGAGLKVIAAKMVHLSRGEAEQFYGVHKERPFFKDLVDFMVSGPVMIQALEGENAILKNRELMGATDPKKAEKGTIRADFADSIDANAVHGSDAAETAAVEVAFFFPGMNVYSR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLV_CAUSK
Sequence: MQNSNSFPDWHGTTILAVRKNGSTVIAGDGQVSMGPTVVKGNARKVRRLAGGKVVAGFAGATADAFTLIERLEAKLEQYPDQLARACVDLAKDWRTDRYLRRLEAMLLVADADSIFTVTGVGDVLEPGESTGGGSVAAIGSGGNYALAAAKALIDQDLTAEEIARKAMGIAAEICVYTNGNLTVESL
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVC_CAMC1
Sequence: MAINVYYDKDCDLSLIQSRKVAIIGFGSQGHAHAENLRDNGVSVVIGLVKGGKSWAKAEAKGFEVKTVSEATKGADVIMILTPDELQAEIYKNEIEPNLKDHAAIAFGHGFNVHFGQIKAPANIDVIMIAPKAPGHTVRSEFLRGGGIPDLIAVEQNASGKAKEIALSYACGIGGGRTGIIETTFKDETETDLFGEQAVLCGGLCALVNAGFDTLVEAGYEPEMAYFECLHELKLIVDLMYQGGMADMRYSISNTAEYGDYVSGVRVVGEESRKAMKEVLKEIQNGKFAKDFILERKAGYVRMNAERGIAERSLLNKTGKKLRAMMPWITNGKLIDQSKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: UPPP_ACIBT
Sequence: MENFEVIKALFLGFVEGLTEFLPISSTGHLILFGHIIDFHSDGGRVFEVVIQLGAILAVCWLYRQKIINLIKGFFSGDVESRHFAISVLIAFFPAVIIGVLAVDFIKSVLFSPIVVAIALIVGALIIFWVESKQFEHKTDDATKITFKQALLVGLAQCVAMIPGTSRSGATIVGGMFAGLSRKAATEFSFFLAMPTMLGAATFDLIKNADVLTSDNMVNIGVGFVAAFIAALLVVKALVLFVERHTLRVFAWYRIVLGVIILIAAMFFNLSA
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYQ_PECCP
Sequence: MSEAEARPTNFIRQIIDEDLASGKHDHIQTRFPPEPNGYLHIGHAKSICLNFGIARDYQGQCNLRFDDTNPVKEDIEYVESIKRDVEWLGFSWSGDVRYSSDYFDQLHAYAVELIGKGLAYVDELTPEQIREYRGTLTAPGKNSPYRDRTVQENLALFEKMRNGGFAEGTACLRAKIDMASSFIVMRDPVLYRIKFADHHQTGNKWCIYPMYDFTHCISDALEGITHSLCTLEFQDNRRLYDWVLDNITIPCHPRQYEFSRLNLEYAIMSKRKLNQLVVENVVEGWDDPRMPTISGLRRRGYSASSIREFCVRIGVTKQDNNVEMAALESCIRDDLNENAPRAMAVLDPVKVVIENLPAGHEEFVAMPNHPNKPEMGSRQVAFSREVYIDRADFREEANKQYKRLVLGKEVRLRNAYVIKADRIEKDEQGTITTIYCSYDAETLSKDPADGRKVKGVIHWVSAAHAVPAEFRLYDRLFSVANPGAAEDFLSTINPDSLKITQGFVEASLAQAEAEKAYQFEREGYFCADRVYSSAEHLVFNRTVGLRDTWVG
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CP17A_PIG
Sequence: MWVLLVFFLLTLTYLFWPKTKGSGAKYPRSLPVLPVVGSLPFLPRRGHQHMNFFKLQDKYGPIFSFRLGSKTTVVIGDHQLAKEVLLKKGKEFSGRPRVMTLDILSDNQKGIAFADHGTSWQLHRKLALSTFSLFKGGNLKLENIINQEIKVLCDFLATRNGESIDLAQPLSLAMTNIVSFICFNFSFKKGDPALQAIVNFNDGILDAVGKEILYDMFPGIRILPSQTLENMKQCVRMRNELLREILENRKENYSRNSITNLLDIMIQAKTNAESNTGGPDHNLKLLSDRHMLATVADIFGAGVETSASVVKWIVAFLLHYPLLRKKIQDAIDQNIGFNRAPSISDRNQLVLLEATIREVLRFRPVSPTLIPHRAIIDSSIGEFTIDKDTDVVVNLWALHHNEKEWHRPDLFMPERFLDPTGTQLISPSLSYLPFGAGPRSCVGEMLARQELFLFTAGLLQRFDLELPDDGQLPCLVGNPSLVLQIDPFKVKIKERQAWKEAHTEGSTS
What is the function of this protein?
A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis.  Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways.  A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage.  The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol.  Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, dehydroepiandrosterone (DHEA) and androstenedione.  Has 16-alpha hydroxylase activity.  Catalyzes 16-alpha hydroxylation of 17-alpha hydroxy pregnenolone, followed by the cleavage of the C17-C20 bond to form 16-alpha-hydroxy DHEA.  Also 16-alpha hydroxylates androgens, relevant for estriol synthesis.  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).
What are the official names of this protein?
Steroid 17-alpha-hydroxylase/17,20 lyase, 17-alpha-hydroxyprogesterone aldolase, CYPXVII, Cytochrome P450 17A1, Cytochrome P450-C17, Cytochrome P450c17, Steroid 17-alpha-monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane. Microsome membrane.
Protein: RINT1_DROME
Sequence: MHAELSEMELRIVARLNEEIGKDASQLHRASHLVSHYKKHLQVLSQTLDYEDPQNVSCYKTAFQCQQQVCESIDFELEKLAHFEDKLKRKLKECQPVLEGVAEDLDKVRQLQRLQQYLLLVQDIQEISAALGNAINGKDEDKLVNIYLTLYEGNDCEHSVVGRLHAVQAQSLKSFAERTAIYWHKLLLKRLSSAFEAVLKSMRWAHLEQQALNYSSARDTAKAQLLAEYMFLIKSPAEERAPLQSITPSIVCQPINRVVQLLLAPYRQRFQFHFTGTRQTNRLDKPEWFYTQILNWGKETHFFVGKTFQPAAIKAGKLDYNLRLEFIRGLVQLAIEKLAVDIEQIAQDQILFAHLLDETLAFESELRETFGYPASFPSAISVITQPMYLLRWISLEERFCAEKMDDILQAETPFQLIDPNSFENDLKIPKCADQFMRLLDAIKDRYYGLIQPGHQLQFLHLQLELIDSFRQRLVQLHSSGAVPSIPILNAINYLVMVLREWGENVHYLHLHAALAGPNATEINSVFEHAVAELEHWARQLMRNLATKATNEMKAKSMSYRRDAWPTMPEQNSREPFILSPSGGEMFQVLVTLLHNLERELSANLFTQTLRLIAHQIDDFMLESMVMNTKFSAAGAAQFNYDMTRNLFALFGQYTRRPELLFKRTHDACKLLAAARGTALLLLETLRGNQSVEEKTKPLRELHVLSMDSKQCIEVLERRMDIKMF
What is the function of this protein?
During cytokinesis in male meiotic cells, required for completion of cleavage furrow ingression possibly in conjunction with Zw10.  Required for maintenance of Golgi stack number and morphology.  Essential for acroblast assembly.
What are the official names of this protein?
RINT1-like protein, DmRINT-1.
What is the protein family that this protein belongs to?
Belongs to the RINT1 family.
Protein: F16PA_CAMJJ
Sequence: MQEVISYIQKAVLEISNALKFPDTGYSQNQNFTGDTQLKFDVLSDEIITKTLSQCSSIKAIISEEKDEILTLNEKANFIVAYDPLDGSSLMDVNFAIGSIFAIYEEKASAKNLRAALYSMYGARLELVICKDQPKLYRLNANNEFIFIKDLKMNEKGKINATGGTQKFWEEKHAKFIKSLFDEGYRLRYSGAMVSDINQILLKGGGIFSYPATQDAPNGKLRAFFEVFPLAFIIEKAGGKTTNGKNHSLLELEFDKIHATTPCFFGSEYEISKLLKAYNE
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDH_SHISS
Sequence: MKKAGLLFLVMIVIAVVAAGIGYWKLTGEESDTLRKIVLEECLPNQQQNQNPSPCAEVKPNAGYVVLKDLNGPLQYLLMPTYRINGTESPLLTDPSTPNFFWLAWQARDFMSKKYGQPVPDRAVSLAINSRTGRTQNHFHIHISCIRPDVREQLDNNLANISSRWLPLPGGLRGHEYLARRVTESELVQRSPFMMLAEEVPEAREHMGSYGLAMVRQSDNSFVLLATQRNLLTLNRASAEEIQDHQCEILR
What are the official names of this protein?
CDP-diacylglycerol pyrophosphatase, CDP-diacylglycerol phosphatidylhydrolase, CDP-diglyceride hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Cdh family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RPC3_NEOFI
Sequence: MRQATELDQSIHCASAANLDLVQFAAELCELLVEENFGELFGRIFATLSRYDRLNLPRLKAYSELPNRQLLPALAAMIQQHLVYHYTSYDDGVTYYEANMQSAYYLVRSGKILEFVEERLGKYAATVLSTIMNLGHAQVSYLETLPELTSEAVKANGVSEEHGEHEEGEEQSNGLNGEHSNEQPELLHPTLKALAAHGYIIRVREAQFQSHADNILDAERVIRSKPEMKALKGKRLEEAVIEGTLGLLKERTDGDLTRGLIVHGVPRGAKRKYSSRRADEPNKKPRTDFASVDEIDEQDEEEENEWLDDEMGYDTTPMESGLVVRVNYNKLDVALRNRRFIELAEQGVSPETAEVYECLLRRIEYQTHQCRDTAEIPREGEEGEQYSVPIALSALAEDVDPRLDLSSSTGPMDTSQPDGRRGKRPLESDVDGTNHEGANGLSSGGNRTFEIDQHLSLLAQPPHNLTSKRMVSGLITWTVEFRHLARKLRHLELERMIEARYGDVALRVVRVLHAKGKLDEKRLQEISLLPFKDLRQVLASMQAGGFVDLQEVPRDAQRQPSRTIYLWYYDPDRICNSVLQDTYKAMSRCLQRLRFERSRIKDFLEKTERSDVKGNEQRFLSEPELVLLEQWRAKEALLLGEVARLDEMVAVMRDY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase III subunit rpc3, RNA polymerase III subunit C3.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MRAY_YERPA
Sequence: MLVWLAEYLVKFYSGFNVFSYLTFRAIVSLLTALFISLWMGPHLIAWLQKLQIGQVVRNDGPESHFSKRGTPTMGGLMILFSITISVLMWAYPSNPYVWCVLFILIGYGIVGFIDDYRKVVRKNTKGLIARWKYFWQSIIALAAAFTMYSIGKDTSATELVVPFFKDIMPQLGLLYVLLAYFVIVGTSNAVNLTDGLDGLAIMPTVFVAAGFALVAWATGNVNFAAYLHIPYLRHAGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGTIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISLMLVLIGLATLKVR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS12_MYCTO
Sequence: MPTIQQLVRKGRRDKISKVKTAALKGSPQRRGVCTRVYTTTPKKPNSALRKVARVKLTSQVEVTAYIPGEGHNLQEHSMVLVRGGRVKDLPGVRYKIIRGSLDTQGVKNRKQARSRYGAKKEKG
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity).
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: BPNT1_MOUSE
Sequence: MASSHTVLMRLVASAYSIAQKAGTIVRCVIAEGDLGIVQKTSATDLQTKADRLVQMSICSSLARKFPKLTIIGEEDLPPGEVDQELIEDGQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGLLDNVTVLIGIAYEGKAIAGIINQPYYNYQAGPDAALGRTIWGVLGLGAFGFQLKEAPAGKHIITTTRSHSNQLVTDCISAMNPDTVLRVGGAGNKIIQLIEGKASAYVFASPGCKKWDTCAPEVILHAVGGKLTDIHGNALQYNKEVKHMNSAGVLAALRNYEYYASHVPESVKNALIP
What is the function of this protein?
Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP.  Has 1000-fold lower activity towards inositol 1,4-bisphosphate (Ins(1,4)P2) and inositol 1,3,4-trisphosphate (Ins(1,3,4)P3), but does not hydrolyze Ins(1)P, Ins(3,4)P2, Ins(1,3,4,5)P4 or InsP6.
What are the official names of this protein?
3'(2'),5'-bisphosphate nucleotidase 1, Bisphosphate 3'-nucleotidase 1, PAP-inositol 1,4-phosphatase, PIP.
What is the protein family that this protein belongs to?
Belongs to the inositol monophosphatase superfamily.
Protein: SCX3_CENSC
Sequence: MNSLLMITACLFLIGTVWAKEGYLVNKSTGCKYGCLKLGENEGCDKECKAKNQGGSYGYCYAFACWCEGLPESTPTYPLPNKSCGKK
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing (By similarity).  Induces immediate paralysis in crickets after injection, with a total paralysis occurring within 15-30 minutes and lasting for 1-2 hours.  Is also lethal to vertebrate (chicks) when injected in very high dosages (more that 100 mg/kg).
What are the official names of this protein?
Toxin CsEv3, CsE v3, Neurotoxin 3.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: APOE_BOVIN
Sequence: MKVLWVAVVVALLAGCQADMEGELGPEEPLTTQQPRGKDSQPWEQALGRFWDYLRWVQTLSDQVQEELLNTQVIQELTALMEETMKEVKAYKEELEGQLGPMAQETQARVSKELQAAQARLGSDMEDLRNRLAQYRSEVQAMLGQSTEELRARMASHLRKLPKRLLRDADDLKKRLAVYQAGASEGAERSLSAIRERFGPLVEQGQSRAATLSTLAGQPLLERAEAWRQKLHGRLEEVGVRAQDRLDKIRQQLEEVHAKVEEQGNQMRLQAEAFQARLRSWFEPLVEDMQRQWAGLVEKVQLALRPSPTSPPSENH
What is the function of this protein?
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids.  APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance.  Apolipoproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma.  As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL).  It also binds a wide range of cellular receptors including the LDL receptor/LDLR and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles.  Finally, APOE has also a heparin-binding activity and binds heparan-sulfate proteoglycans on the surface of cells, a property that supports the capture and the receptor-mediated uptake of APOE-containing lipoproteins by cells.
What are the official names of this protein?
Apolipoprotein E, Apo-E.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix. Note=In the plasma, APOE is associated with chylomicrons, chylomicrons remnants, VLDL, LDL and HDL lipoproteins. Lipid poor oligomeric APOE is associated with the extracellular matrix in a calcium- and heparan-sulfate proteoglycans- dependent manner. Lipidation induces the release from the extracellular matrix.