PharMolix/UniProtQA huggingface dataset:
Protein: MUTS_STRPD
Sequence: MAKTNISPGMQQYLDIKKNYPDAFLLFRMGDFYELFYEDAVKAAQLLEIGLTSRNKNAENPIPMAGVPHHSAQQYIDVLIELGYKVAVAEQMEDPKQAVGVVKREVVQVITPGTVVDSAKPDSANNFLVAVDFDGCRYGLAYMDVSTGEFCVTDLADFTSVRSEIQNLKAKEVLLGFDLSEEEQTILVKQMNLLLSYEETVYEDKSLIDGQLTTVELTAAGKLLQYVHKTQMRELSHLQALVHYEIKDYLQMSYATKSSLDLVENARTNKKHGSLYWLLDETKTAMGMRLLRSWIDRPLVSKEAILERQEIIQVFLNAFIERTDLSNSLKGVYDIERLSSRVSFGKANPKDLLQLGHTLAQVPYIKAILESFDSPCVDKLVNDIDSLPELEYLIRTAIDPDAPATISEGSIIRNGFDERLDHYRKVMREGTGWIADIEAKERQESGINNLKIDYNKKDGYYFHVTNSNLSLVPEHFFRKATLKNSERYGTAELAKIEGQMLEAREESSSLEYDIFMCIRAQVETYINRLQKLAKTLATVDVLQSLAVVAETNHYIRPQFNDNHVITIQEGRHAVVEKVMGVQEYIPNSISFDQQTSIQLITGPNMSGKSTYMRQLALTVIMAQMGSFVAADHVDLPLFDAIFTRIGAADDLISGQSTFMVEMMEANQAIKRASDNSLILFDELGRGTATYDGMALAQAIIEYIHDRVGAKTIFATHYHELTDLSTKLTSLVNVHVATLEKDGDVTFLHKIAEGPADKSYGIHVAKIAGLPKSLLKRADEVLTRLETQSRSTEIMSVPPQVESSSAVRQGQLSLFGDDEKAHEIRQALEAIDVMNMTPFQAMTTLYELKKLL
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: FDHD_SALCH
Sequence: MNNILFEEVLNVTDFTTSRQLTLWKREDLQSPQLDDVAEEVPVALVYNGISHVVMMASPKDLTHFAMGFSLSEGIIDSPREIYGMDVVPSCNGLEVQIDLSSRRFMGLKARRRALAGRTGCGVCGVEQLNDIGKPVQPLPFSQTFNLGNLDRALKHLNDFQPTGKLTGCTHAAAWVMPSGELAGGHEDVGRHVALDKLLGRRATEGEEWRQGAALVSSRASYEMVQKSAMCGVEILFAVSAATTLAVDVAERCNLTLVGFCKPGRATIYTHPQRLIAD
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity.  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
What are the official names of this protein?
Sulfur carrier protein FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLO_THEP1
Sequence: MIYYGTMFDHKVRFSIVRMREVVEEARNRHSLSYLATVVLGRALIGAALVTPWLAEKERWTLDIEGNGPIRRVVAQSTSEFTVRGYVANPKVELPLNEKGKFDVAGAIGQGVLRVVRDLGLKTPFVSQLPLVSGEIAEDLAYYFAVSEQIPSAFSIGVLVDSGGVKIAGGFAVQIIDRTLEQEKVELIERNIKNLPYITELFQKAEPLDVLERIFGEKVGFVETAEIRYKCDCNREKAKNALLVLDKKELEDMRKEGKGEVVCKWCNTKYVFSEEELEELLKFKVDNSGS
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_NITWN
Sequence: MEIILLERVAKLGQMGEVVKVKDGFARNFLLRRGKALRATAENRAKYDGMKAELEANNIKAKGEAATVAEKINGRDIVVIRQASETGQLFGSVTVRDIVAALAADGIIVSRPQVWLDAPIKTIGQQKLTVAVHPEVEAEITVTVARSVDEAERIQRGEDISTRREDRDAAAEAIAAAGEFFDPDAQHDDEPAAEDDQNAEEK
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: G6PI_CAMJE
Sequence: MLNNTLFFKQSEIHTISSYANRINDEVKSGDIGYYHLIDTSLNLIDESLQFIQDKEYVKNIVLVGMGGSSCGVKALRDMLFNEKSNQRELFILDNTSSHSFNKTLEKIKLEESLFLIISKTGSTIEVVSLFKLLIEHFKLDMQELKKYFVFITDKDSKLHQEGENLGIKCFFIPANVGGRFSILSAVGIVPLCFCGYNAKALLEGAKACFEDFFTHKKDEILQKAYHYCTHKNANINVLFSYSDAFKGFNEWYIQLIAESLGKKQGYKRIGLTPIALIGARDQHSFLQLIMDGPKNKTVTFLKIKDAQKAPIIPDIHFKFLDSLSNKVNLHELLNAQCDATMHALIAENLSVDVIELEKLDAWHAGYLMYYYELFTSTCGVMLGINTYDQPGVEVGKLILKNILNS
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SODC_DROPB
Sequence: INGDAKGTVFFEQETSEAPVKVTGEGLGLAKGLHGFHVHEFGDNTNGCMSSGPHFNPRNKEHGAPTDENRHLGDLGNIQAAGDSPTAVSITDSKITLFGADSIIGRTVVVHADA
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn], Superoxide dismutase 1.
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INA17_ASHGO
Sequence: MIRYALLRSGRRTLQTRPSPQTLEELARLKSLEDVDSSVIRKLINQRTEEVNAQNEAQMLKKLSAEGRDLQNVPGSRYARPLWLLLIGCASVYLVRDWLRMKAEYDARETTLETRVEGLEAELKYLLEPKPGVLEVEVVQTEVASSAPWYKRWLWSGSR
What is the function of this protein?
Component of the INA complex (INAC) that promotes the biogenesis of mitochondrial F(1)F(0)-ATP synthase.  INAC facilitates the assembly of the peripheral stalk and promotes the assembly of the catalytic F(1)-domain with the membrane-embedded F(0)-domain.
What are the official names of this protein?
Inner membrane assembly complex subunit 17.
What is the protein family that this protein belongs to?
Belongs to the INA17 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: PP186_ARATH
Sequence: MLVAGNALNCLFIDSSGFQRYLGFGVTNLNGATVKSYKQEGFVIDERGKLKRFNRKKLSRKRCGSLRGRGWKYGSGFVDGIFPVLSPIAQKILSFIQKETDPDKVADVLGALPSTHASWDDLINVSVQLRLNKKWDSIILVCEWILRKSSFQPDVICFNLLIDAYGQKFQYKEAESLYVQLLESRYVPTEDTYALLIKAYCMAGLIERAEVVLVEMQNHHVSPKTIGVTVYNAYIEGLMKRKGNTEEAIDVFQRMKRDRCKPTTETYNLMINLYGKASKSYMSWKLYCEMRSHQCKPNICTYTALVNAFAREGLCEKAEEIFEQLQEDGLEPDVYVYNALMESYSRAGYPYGAAEIFSLMQHMGCEPDRASYNIMVDAYGRAGLHSDAEAVFEEMKRLGIAPTMKSHMLLLSAYSKARDVTKCEAIVKEMSENGVEPDTFVLNSMLNLYGRLGQFTKMEKILAEMENGPCTADISTYNILINIYGKAGFLERIEELFVELKEKNFRPDVVTWTSRIGAYSRKKLYVKCLEVFEEMIDSGCAPDGGTAKVLLSACSSEEQVEQVTSVLRTMHKGVTVSSLVPKLMAKSLTVN
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At2g35130.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
Protein: MTNA_METST
Sequence: MIRTLYWENNRLFLLDQTKLPHTIEYVECRTYTDVIDGIKTMKVRGAPAIGVSAAYGMALGELAGEDMDVIGDEIKSARPTAVNLFWAVDKVLDLVSRGKSAVDVAIEMEKDDVAINKKIGEYGNSIIDDNDTILTHCNAGALACAGYGTALGVIRAAHEANKNIDVICDETRPVLQGARLSVFEMQQENIPVRLIVDGAAGHMMQKGEVDKVIIGADRVAKDGVANKIGSLMVALAAKRYDIPFYVAAPMSTFDFENNIFDTIIEQRLPEEVLCINGKYISKKQTNVENPAFDIVESDLITGIITEEGIKKPL
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Putative methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, MTNA-like protein, aMTNA, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: LMBD2_MOUSE
Sequence: MSGAALGLEIVFVFFLALFLLHRYGDFKKQHRLVIIGTLLAWYLCFLIVFILPLDVSTTIYNRCRHAAANSSPPENTNVTGLDASVTPAPRQHPCFKPWSYIPDGIMPIFWRVVYWTSQFLTWILLPFMQSYARSGGFSITGKIKTALIENAIYYGTYLLIFGAFLIYVAVNPRLHLEWNQLQTIGIAAANTWGLFLLVLLLGYGLVEIPRSYWNGAKRGYLLMKTYFKAAKLMTEKADAEENLEDVMEEVRKVNESIKYNHPLRKCVDTILKKCPTDYQEKMGRNMDDYEDFDEKRNTYPSEKSLVKLHKQVIYSVQRHRRTQVQWQILLEQAFYLEDVAKNETSATHQFVHTFQSPEPENRFIQYFYNPTVEWYWECLLRPWFHRTLAVVLSIFSVIVVWSECTFFSTTPVLSLFAVFIQLAERTYNYIYIEIACFLSIFFLSICVYSTVFRIRVFNYYYLASHHQTDAYSLLFSGMLFCRLTPPLCLNFLGLTHMDSSISHQNTQPTAYTSIMGSMKVLSFIADGFYIYYPMLVVILCIATYFSLGTRCLNLLGFQQFMGDNDMTSDLVDEGKELIRREKRKRQRQEEGENRRREWKERYGHNREDSTRNRNVHPDPKESNFSDTTTNWSSKYTRANNRTERDRIELLQDAEPLDFNAETFTDESLEPESGRYQPGGRYLSMSSSIIFEDI
What is the function of this protein?
Recruited to ligand-activated beta-2 adrenergic receptor/ADRB2, it negatively regulates the adrenergic receptor signaling pathway.  May also regulate other G-protein coupled receptors including type-1 angiotensin II receptor/AGTR1.
What are the official names of this protein?
G-protein coupled receptor-associated protein LMBRD2, LMBR1 domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the LIMR family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ACCA_LISMH
Sequence: MANEMEFEKPILELKSKIADLKEYNETSDVDLTNEIEKLEKRLGKLESSIYSNMTAWDKFQVARHPERPTTLDYISLLFEDFMELHGDRAFGDDAAIVGGIATFKGVPVTVIGHQRGKDTKDNLHRNFGMPHPEGFRKALRLMKQADKFGRPIICFIDTKGAYPGRAAEERGQSEAIARNLYEMSDMKVPIISIVIGEGGSGGALALGVGNQIFMLENAVFSVISPEGAAAILWKDASQAKKAAESMRITAGDLFELGITDGIIPEVKGGAHRDLNAQAEEINKTITKSLHALMAFSEEQLIEQRYEKFKKIGVYDTL
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATB_PSEFS
Sequence: MQWEVVIGLEIHTQLATQSKIFSGSATTFGSEPNTQASLVDLGMPGVLPVLNQEAVRMAVMFGLAIDAEIGQHNVFARKNYFYPDLPKGYQISQMELPIVGKGYLDIPLEDGTIKRVGVTRAHLEEDAGKSLHEEFNGATGIDLNRAGTPLLEIVSEPDMRSAKEAVAYVKTIHALVRYLGICDGNMAEGSLRCDCNVSVRPKGQAEYGTRCEIKNVNSFRFIEKAINTEVRRQIELIEDGGKVIQQTRLYDPNKDETRAMRSKEEANDYRYFPDPDLLPVVIEDSFLNDIRATLPELPPQKRERFQAQFGLSVYDASVLASSREQADYFEKVVSIAGDAKLAANWVMVELGSLLNKQGLEIDEAPVTAEQLGGMLLRIKDNTISGKIAKTVFEAMASGEGSADEIIEKRGLKQVTDSGAISAVLDEMLAANAEQVKQYRAADEAKRGKMFGFFVGQAMKASKGKANPQQVNELLKSKLEG
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: PETD_PSINU
Sequence: MGVTKKPDLNDPVSRAKLAKGMGHNYYGEPAWPNDLLYIFPIVILGTIACIAGLAVLEPSMIGEPANPFATPLEILPEWYFYPVFQILRTVPNKLLGVLLMASVPAGLLTVPFLENVNKFQNPFRRPVATTVFLIGTVVAIWLGIGAALPIDRSLTLGLF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 4, 17 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetD subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: 2ABD_HUMAN
Sequence: MAGAGGGGCPAGGNDFQWCFSQVKGAIDEDVAEADIISTVEFNYSGDLLATGDKGGRVVIFQREQENKSRPHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQQNAAHFLLSTNDKTIKLWKISERDKRAEGYNLKDEDGRLRDPFRITALRVPILKPMDLMVEASPRRIFANAHTYHINSISVNSDHETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPHQCNVFVYSSSKGTIRLCDMRSSALCDRHSKFFEEPEDPSSRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKVWDLNMESRPVETHQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSAIMTGSYNNFFRMFDRDTRRDVTLEASRESSKPRASLKPRKVCTGGKRRKDEISVDSLDFNKKILHTAWHPVDNVIAVAATNNLYIFQDKIN
What is the function of this protein?
B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit.  The activity of PP2A complexes containing PPP2R2D (PR55-delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis.  During mitosis, activity of PP2A is inhibited via interaction with phosphorylated ENSA and ARPP19 inhibitors.  Within the PP2A complexes, the B regulatory subunits modulate substrate selectivity and catalytic activity, and may also direct the localization of the catalytic enzyme to a particular subcellular compartment (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform, PP2A subunit B isoform B55-delta, PP2A subunit B isoform PR55-delta, PP2A subunit B isoform R2-delta, PP2A subunit B isoform delta.
What is the protein family that this protein belongs to?
Belongs to the phosphatase 2A regulatory subunit B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUTB_SHIF8
Sequence: MMTTLTARPEAITFDPQQSAQIVVDMQNAYATPGGYLDLAGFDVSTTRPVIANIQTAVTAARAAGMLIIWFQNGWDEQYVEAGGPGSPNFHKSNALKTMRKQPQLQGKLLAKGSWDYQLVDELVPQPGDIVLPKPRYSGFFNTPLDSILRSRGIRHLVFTGIATNVCVESTLRDGFFLEHFGVVLEDATHQAGPEFAQKAALFNIETFFGWVSDVETFCDALSPTSFARIA
What is the function of this protein?
Hydrolyzes ureidoacrylate to form aminoacrylate and carbamate.  The carbamate hydrolyzes spontaneously, thereby releasing one of the nitrogen atoms of the pyrimidine ring as ammonia and one of its carbon atoms as CO2.
What are the official names of this protein?
Ureidoacrylate amidohydrolase RutB.
What is the protein family that this protein belongs to?
Belongs to the isochorismatase family. RutB subfamily.
Protein: PURR_SALPK
Sequence: MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWTAIKELHYSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLEKQRAYLSMMAQKRVDGLLVMCSEYPEPLLSMLEEYRHIPMVVMDWGEAKADFTDTVIDNAFAGGYMAGRYLVERGHRDIGVIPGPLERNTGAGRLAGFMKAMEEALINVPDNWIVQGDFEPESGYHAMQQILSQSHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSVIGYDNVRNARYFTPALTTIHQPKDSLGETAFNMLLDRIVNKREESQSIEVHPRLVERRSVADGPFRDYRR
What is the function of this protein?
Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression.  PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.
What are the official names of this protein?
HTH-type transcriptional repressor PurR, Pur regulon repressor, Purine nucleotide synthesis repressor.
Protein: ARI3A_XENTR
Sequence: MKLQAVMETLQRQQRARLQQELEARQLQQDSSEGRTPPSVGYPGNGSEEAEPEALKIQRAQAAALAAMRAAAAGLSQQPSPAASDEEEEDGESMASDEEDEKERDGESERYPDMGSEEEDLKGKWDEDDFEDEGEEDDYEDMEEGMGVSEAGRVGKGSTLPPKHPNPQAFPTQRSVGAERAGLPHTGHPQLQDHGDWTYEEQFKQLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLYMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAIDSNRREGRRQSFGGSLFTYSPSGAPSMLSSPKLQVSALSLGGVATNGSSLSSMQKIKKEEDSPISLTVPPRIPVSLAGHSMVAAQVAAQAAALEQLREKLESGEPPEKKMALGTEEQQRLQRAIQHNLLAMTAQLPMNIRINSQAEGRQDSAVNLTTNGTNSISMSVELNGIVYTGVLFAQPPTSASGTSKGSSNRTGSIGGGSSTSQAAPPPAPSAPTSNNPSP
What is the function of this protein?
Transcription factor required for smad1 and smad2-mediated responses to TGFbeta during mesoderm induction.
What are the official names of this protein?
AT-rich interactive domain-containing protein 3A, ARID domain-containing protein 3A, Bright homolog, Dead ringer-like protein 1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between nucleus and cytoplasm.
Protein: PYRI_SHISS
Sequence: MTHDNKLQVEAIKRGTVIDHIPAQIGFKLLSLFKLTETDQRITIGLNLPSGEMGRKDLIKIENTFLSEDQVDQLALYAPQATVNRIDNYEVVGKSRPSLPERIDNVLVCPNSNCISHAEPVSSSFAVRKRANDIALKCKYCEKEFSHNVVLAN
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: CKI1_ORYSJ
Sequence: MEHVIGGKFKLGRKIGSGSFGELYLGVNIQSSEEVAIKLESVKSRHPQLHYESKLYMLLQGGTGIPHLKWFGVEGEYNVMVIDLLGPSLEDLFNYCNRKFSLKTVLMLADQMINRVEYMHTRGFLHRDIKPDNFLMGLGRKASQVYVIDYGLAKKYRDLQTHKHIPYRENKNLTGTARYASVNTHLGVEQSRRDDLESLGYVLMYFLRGSLPWQGLKAGTKKQKYDKISEKKMLTPVEVLCKSYPTEFISYFHYCRSLRFEDKPDYSYLKRLFRDLFIREGYQLDYIFDWTKQGSESNRLRSSGRTSGLVGPSAERTERAAARQDVPDRFSGTVDPFARRTGSGSGHYGEHTKHRNILDSLLAPKTAVDLDKRRPTSSSRNGSTSRKALLSSSRPSSGDPIDPNRSNLIPTSSGSSRPSTMQRLHQSTGLETRSSLTKTARNVHDDPTLRTFERLSISADRRK
What is the function of this protein?
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates.  Can phosphorylate casein in vitro.  Required for normal root development through modulation of cell elongation.  Plants silencing CKI1 show abnormal root development, with reduced number of lateral and adventitious roots, and shortened primary roots as a result of reduced cell elongation.  May be involved in abscisic acid (ABA) and brassinosteroid (BR) signaling pathways (PubMed:14535884).  Plays an important role in the adaptive growth and fitness under low temperature (LT) conditions.  May confer tolerance to LT through an auxin-dependent process (PubMed:24635058).
What are the official names of this protein?
Casein kinase 1, OsCKI1, Protein HYBRID BREAKDOWN 2, Protein LOW TEMPERATURE GROWTH 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: VAMP2_BOVIN
Sequence: MSATAATAPPAAPAGEGGPPAPPPNLTSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNLKMMIILGVICAIILIIIIVYFSS
What is the function of this protein?
Involved in the targeting and/or fusion of transport vesicles to their target membrane (By similarity).  Major SNARE protein of synaptic vesicles which mediates fusion of synaptic vesicles to release neurotransmitters.  Essential for fast vesicular exocytosis and activity-dependent neurotransmitter release as well as fast endocytosis that mediates rapid reuse of synaptic vesicles (By similarity).  Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 (By similarity).
What are the official names of this protein?
Vesicle-associated membrane protein 2, VAMP-2, Synaptobrevin-2.
What is the protein family that this protein belongs to?
Belongs to the synaptobrevin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type IV membrane protein. Cell membrane. Note=Colocalizes with PRKCZ and WDFY2 in intracellular vesicles.
Protein: URE2_PSEA7
Sequence: MIPGEYDIQPGDIELNAGRRTLALSVANTGDRPIQVGSHYHFFEVNDALAFDRPATRGMRLNIAAGTAVRFEPGQSREVELVELAGERRVYGFAGRVMGDL
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BMP2_RABIT
Sequence: MVAGTRCLLALLLPQVLLGGAAGLIPELGRRKFAASSGRPSPQPSDDILSEFELRLLSMFGLKQRPTPSRDAVVPPYMLDLYRRHSGQPGAPAPDHRLERAASRANTVRSFHHEESLEELPETSGKTTRRFFFNLTSIPPEEFITSAELQVFREQMQEALGDDSGFHHRINIYEIIKPATANSKFPATRLLDTRLVNQNTSRWESFDVTPAVMRWTAQGHANHGFVVEVTHLEEKQGVSKRHVRISRSLHPDEHSWSQIRPLLVTFGHDGKGHPLHRREKRQAKHKQRKRLKSSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR
What is the function of this protein?
Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including cardiogenesis, neurogenesis, and osteogenesis.  Induces cartilage and bone formation.  Initiates the canonical BMP signaling cascade by associating with type I receptor BMPR1A and type II receptor BMPR2.  Once all three components are bound together in a complex at the cell surface, BMPR2 phosphorylates and activates BMPR1A.  In turn, BMPR1A propagates signal by phosphorylating SMAD1/5/8 that travel to the nucleus and act as activators and repressors of transcription of target genes.  Can also signal through non-canonical pathways such as ERK/MAP kinase signaling cascade that regulates osteoblast differentiation.  Stimulates also the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A-ATF4 pathway by stimulating EIF2A phosphorylation which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation.
What are the official names of this protein?
Bone morphogenetic protein 2, BMP-2.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y4FB_SINFN
Sequence: MEISKFADEQLADQIAAGREAVPEVDPIRLIEQVVHRARAGAGVDFDVFESLIGEIDLVEINYLERGLMASRAVCRINVPAPVGDSSDWGTGFLIGPRLLLTNNHVIDSAEDALKATVEFGYELDAEGRLKRTTRFRLSPQDGFVTSPRDALDYTVVAIEENSEDGATPISDFGFLRLDARTGKTEVGQYATIIQHPDAKTKRISLRENKFVKYGDEADPERDNFLWYSSDTANGSSGAAVFTDAWQVVCLHHAGVPDRRMIDGKEHWVLTDKTTAPARIAINLPVDKVHWLANEGVRISKLIADVQERIAAPGFARSTLVDDLVADATGVKAFAGTTPGESIVGPPLVAAPALRLVAAEARRRPTRHTHPANYFDGREGYRSDFLPVEIPLPTLGVNALRHGSPAKVTGAADDVLRYQHFSVVLNANPKRKMAFYTAVNIDGARWTNLERGNDVWFYDPRIPEELQNGDELYGDEPVPSKNYFDRGHLVRRLDPVWGEIRVAKQANDDTFQWTNCSPQYWGFNQGADLWQGLENFLLYNTDDENVQASVFSGPLFRADDEEHRGILIPQFFWKVIAVTDKNDRLYTSGYMVSQQDYALDIPFERLPVGPNSTKPGQNFQVPVAKIIEDTGIVFADEILSADAYSGPSTGRALRTVADIQHPRR
What are the official names of this protein?
Uncharacterized protein y4fB.
Protein: RS19_AKKM8
Sequence: MGRSLKKGPFVSQKLLAKIDAQLESGDRKPIKTWSRASMITPDFVGLTFLVHAGKNFATVYVTENMVGHKLGEFAPTRVFKQHGGIGKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: LSPA_STAAC
Sequence: MHKKYFIGTSILIAVFVVIFDQVTKYIIATTMKIGDSFEVIPHFLNITSHRNNGAAWGILSGKMTFFFIITIIILIALVYFFIKDAQYNLFMQVAISLLFAGALGNFIDRILTGEVVDFIDTNIFGYDFPIFNIADSSLTIGVILIIIALLKDTSNKKEKEVK
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NU3C_ACOCL
Sequence: MFLLHEYDIFWAFLLISSVIPILAFLISGVLAPTREGPEKLSSYESGIEPIGDAWVQFRIRYYMFALVFVVFDVETVFLYPWAMSFDVLGVSVFLEALIFVLILIVGSVYAWRKGALEWS
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic, NAD(P)H dehydrogenase subunit 3, NADH-plastoquinone oxidoreductase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: CYBC1_DANRE
Sequence: MGYMIVEKHTSELLHLKRSPGIRSWSILVGIASVGLAAAYYSSDSILWKMFYVTGCFFVALQNMEEWEEAVFNKSKNEIELKTFSLYTMLLTLWKRGHEKVLLDLRHLRDVSVQEERVRYLGKGYLVVLRLATGFSYPLTQSATLGSRSDVEALAALLKRFLGLEELQQRLADDDYPDDDDGIEDLGLGDSSDSQDDPDGDDDEEH
What is the function of this protein?
Functions as a chaperone necessary for a stable expression of the CYBA and CYBB subunits of the cytochrome b-245 heterodimer.
What are the official names of this protein?
Cytochrome b-245 chaperone 1 homolog, Essential for reactive oxygen species protein, Eros.
What is the protein family that this protein belongs to?
Belongs to the CYBC1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.