PharMolix/UniProtQA huggingface dataset:
Protein: BTCB_NEOBT
Sequence: MDAMNGSDVQSDGLPNGNTLQLAYHVMPRLVQDMGPSLLLIFGPLVLVSSCIYYLFFHPLSKIPGPKLAAISPVWMMKSLYGKKLNRDIKALHDRYGDVVRVGPNTVSFATVGALSSVHHEKAGGDDGTFTKEGTIEWLLGLMTWPAQNILTKTDVKGHARLRKAVQPAFSAKELRKQEPIEQEWITKFNRLLDAAAVDNTEVNITEHMSHLVWDMLSDLSFGEPLARSQLVKFNRLKWLACAMSPMLEVMQSILTFPIAGAFTRWIVTSFPQVFQLPRDILPTGTLRTTLERADRGHDFLSAIVGAQEKGIVLSQDELQSNSAMLVMVGQDATVTCLSSTLYFLLRDPQHMANLQDEVRGQFKSEDEINGLAIARLPLLNGSINEAMRLLSPANGTGTHRLSNGGFVEGIYLPAGITVAVDQYTIQRSPKYWRDPETYRPERWASVGEPESEFENDVHSAYRPFLLGPRACLGRELALQIVRLVLARLVFSYDLRMVNRDFVWERDCDSSYLWLGHKVVVKVQKRES
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of betaestacins (PubMed:29185768, Ref. 2).  The bifunctional terpene synthase btcA converts isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) into the sesterterpene betaestacin I (PubMed:29185768, Ref. 2).  The C-terminal prenyltransferase (PT) domain of btcA catalyzes formation of GFPP, whereas the N-terminal terpene cyclase (TC) domain catalyzes the cyclization of GFPP into betaestacin I (PubMed:29185768, Ref. 2).  The cytochrome P450 monooxygenase btcB is then responsible for the six-step oxidation of betaestacin I to yield betaestacin II (Ref. 2).  The roles of the cytochrome P450 monooxygenase btcC and the alpha-ketoglutarate-dependent dioxygenase btcD have not been identified yet (Probable).
What are the official names of this protein?
Cytochrome P450 monooxygenase btcB, Betaestacins biosynthesis cluster protein B.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL14_LEIDO
Sequence: MVKSHYICAGRLVRILRGPRQDRVGVIVDIVDANRVLVENPEDAKMWRHVQNLKNVEPLKYCVSVSRNCSAKALKDALASSKALEKYAKTRTAARVEAKKACAASTDFERYQLRVARRSRAHWARKVFDEKDAKTPVSWHKVALKKMQKKAAKMDSTEGAKRRMQKAIAARKAKK
What are the official names of this protein?
Probable 60S ribosomal protein L14, 23 kDa cell surface protein, LDP 23.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL14 family.
Protein: RPIA_CUPTR
Sequence: MTQDELKALVAQAAADYVKQEVPEGAVLGVGTGSTANLFIDAVAAFKDRFAGAVSSSEASTRRLQQHGFKVLDLNEVDEIPVYVDGADEIDASGAMVKGGGGALTREKIVASVARRFVCIADGSKLVQTMGAFPLPVEVVPMARAAVARKLQALGGQPRLRMTKEGGIYKTDNGNVILDVAGLKIDDPRGLEQTINQVPGVVTVGLFALRGADVLLLGTGDGVQRTDY
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: PIM3_MOUSE
Sequence: MLLSKFGSLAHLCGPGGVDHLPVKILQPAKADKESFEKVYQVGAVLGSGGFGTVYAGSRIADGLPVAVKHVVKERVTEWGSLGGVAVPLEVVLLRKVGAAGGARGVIRLLDWFERPDGFLLVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHNCGVVHRDIKDENLLVDLRSGELKLIDFGSGAVLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMVCGDIPFEQDEEILRGRLFFRRRVSPECQQLIEWCLSLRPSERPSLDQIAAHPWMLGTEGSVPENCDLRLCALDTDDGASTTSSSESL
What is the function of this protein?
Proto-oncogene with serine/threonine kinase activity that can prevent apoptosis and promote cell survival and protein translation.  May contribute to tumorigenesis through: the delivery of survival signaling through phosphorylation of BAD which induces release of the anti-apoptotic protein Bcl-X(L), the regulation of cell cycle progression and protein synthesis and by regulation of MYC transcriptional activity.  Additionally to this role on tumorigenesis, can also negatively regulate insulin secretion by inhibiting the activation of MAPK1/3 (ERK1/2), through SOCS6.  Involved also in the control of energy metabolism and regulation of AMPK activity in modulating MYC and PPARGC1A protein levels and cell growth.
What are the official names of this protein?
Serine/threonine-protein kinase pim-3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATK_QUECE
Sequence: MEEFQGYLELDRFRQHDFLYPFIFREYSYALAHGHGLNRYMLLENIGYDNKSSLLIVKRLITTMYQQNYLIISANDSKQNPFFGYNKNLHSKILSEGFAIIVEIPFYLRLISSLEGAEIVRFYNLRSIHSIFPFLEEKFPHLNYSADILIPYPAHLEILVQTLRYRVKDASYLHLLRFFLHEYSNCNSLIITNKSISIFSKSNPRFFLFLYNSYLCEYESIFLFLRNQSSHLRLTSSGVLFERLCLYRKIEHFAEVFANDFPVIPCFLKDPFMHYVRYQGKSILASKDTPLLMNKWKSYLVNLWQCHFDVWSHAASIRINQLSKHSLDFLSYFSSVRRNPAVVRNQMLENSFLLNNAPNKLDTIVPIIPLIGSLAKAKFCNAVGHPISKLTRADLSDFEIINRFLHICRNLSHYYSGSSKKKNMYRIKYILRLSCVKTLARKHKSTARAFLKRVDSEFFQEFFTEEGGFISLIFPRASFALRRLYSGRVWYLDIIFINGLSNHE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TX1AB_ECTBR
Sequence: FAIGAIIKKFGKKLVEYAVKHKDLYAPYIKKHLCEKL
What are the official names of this protein?
U1-ectatotoxin-Eb1a subunit B, U1-ECTX-Eb1a subunit B, Ectatomin-Eq1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the ectatomin family. Ectatomin-Eq subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: NPRE_BACCL
Sequence: MNKRAMLGAIGLAFGLMAWPFGASAKGKSMVWNEQWKTPSFVSGSLLGRCSQELVYRYLDQEKNTFQLGGQARERLSLIGNKLDELGHTVMRFEQAIAASLCMGAVLVAHVNDGELSSLSGTLIPNLDKRTLKTEAAISIQQAEMIAKQDVADRVTKERPAAEEGKPTRLVIYPDEETPRLAYEVNVRFLTPVPGNWIYMIDAADGKVLNKWNQMDEAKPGGAQPVAGTSTVGVGRGVLGDQKYINTTYSSYYGYYYLQDNTRGSGIFTYDGRNRTVLPGSLWADGDNQFFASYDAAAVDAHYYAGVVYDYYKNVHGRLSYDGSNAAIRSTVHYGRGYNNAFWNGSQMVYGDGDGQTFLPFSGGIDVVGHELTHAVTDYTAGLVYQNESGAINEAMSDIFGTLVEFYANRNPDWEIGEDIYTPGVAGDALRSMSDPAKYGDPDHYSKRYTGTQDNGGVHTNSGIINKAAYLLSQGGVHYGVSVTGIGRDKMGKIFYRALVYYLTPTSNFSQLRAACVQAAADLYGSTSQEVNSVKQAFNAVGVY
What is the function of this protein?
Extracellular zinc metalloprotease.
What are the official names of this protein?
Bacillolysin, Thermostable neutral protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase M4 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL20_CITK8
Sequence: MARVKRGVIARARHKKILKQAKGYYGARSRVYRVAFQAVIKAGQYAYRDRRQRKRQFRQLWIARINAAARQNGISYSKFINGLKKASVEIDRKILADIAVFDKVAFTALVEKAKAALA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: NDHH_MICAN
Sequence: MAKIETRTEPMVLNMGPHHPSMHGVLRLIVTLDGEDVIDCEPVIGYLHRGMEKIAENRTNVMYVPYVSRWDYAAGMFNEAITVNAPEKLADIAVPKRAQYIRVIMLELNRIANHLLWLGPFMADVGAQTPFFYIFREREMIYDLWEAATGMRLINNNYFRIGGVAVDLPYGWVDKCVDFCDYFDPKVDEYEKLITNNPIFRRRIEGIGCITRDEAINWGLSGPMLRASGVKWDLRKVDHYECYDDFDWEVHWETAGDCFARYLVRIREMRESVKIIRQALKGLPGGPYENLEAKRMAEGKKSAWNDFDYQYIAKKVAPTFKIPKGEHYVRLESGKGELGIFIVGNDDVFPWRWKIRAADFNNLQILPHILKGVKVADIMAILGSIDIIMGSVDR
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit H, NAD(P)H dehydrogenase subunit H, NADH-plastoquinone oxidoreductase subunit H, NDH-1 subunit H, NDH-H.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CC194_HUMAN
Sequence: MAEPGPEPGRAWRVLALCGVAVFLAAAAAGGALVAWNLAASAARGPRCPEPGANATAPPGDPPPGVDDLRRRLAEAAEREEALARQLDQAESIRHELEKALKACEGRQSRLQTQLTTLKIEMDEAKAQGTQMGAENGALTEALARWEAAATESTRRLDEALRRAGVAEAEGEACAAREAALRERLNVLEAEMSPQRRVPRPRPRSGSRPRPSPRSRSRSGPSGGCRRPARRARG
What are the official names of this protein?
Coiled-coil domain-containing protein 194.
Protein: RNPA_UREP2
Sequence: MANFISLKKNEDILDTIKKQQKIHSNQIVVYFRKTNLKNVRLAISISKKKFKLATQRNRIRRLIKAWFIAADIPIKSYDIVVLVKPSFIDGSFVLNCNNLKIILQRIINKEKR
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: PEPX_STRPM
Sequence: MRYNQFSYIPTSLERAAEELKELGFDLDLQKTAKANLESFLRKIFFHYPDSDYPLSHLIAKNDMDALSFFQSEQELSKEVFDLLALQVLGFIPGVDFTEADAFLDKLAFPIHFDETEIIKHIHHLLATRCKSGMTLIDDLVSQGMLTMDNDYHFFNGKSLATFDTSQLIREVVYVEAPLDTDQDGQFDLIKVNIIRPQSQKPLPTLMTPSPYHQGINEVANDKKLYRMEKELVVKKRRQITVEDRDFIPLETQPCKLPIGQNLESFSYINSYSLNDYFLARGFANIYVSGVGTAGSTGFMTSGDYAQIESFKAVIDWLNGRATAYTSHSKTHQVRADWANGLVCTTGKSYLGTMSTGLATTGVDGLAMIIAESAISSWYNYYRENGLVCSPGGYPGEDLDVLTELTYSRNLLAGDYLRHNDHYQELLNQQSQALDRQSGDYNQFWHDRNYLKNAHQIKCDVVYSHGLQDWNVKPRQVYEIFNALPSTINKHLFLHQGEHVYMHNWQSIDFRESMNALLCQKLLGLANDFSLPEMIWQDNTCPQNWQERKVFGTSTIKELDLGQELLLIDNHYGEDEFKAYGKDFRASKAALFKGKANQALIDILLEEDLPINGEIVLQLKVKSSENKGLLSAQILDYGKKKRLGDLPIALTQSSIDNGQNFSREPLKELPFREDSYRVISKGFMNLQNRNNLSSIETIPNNKWMTVRLPLQPTIYHLEKGDTLRVILYTTDFEHTVRDNSNYALTIDLSQSQLIVPIASN
What is the function of this protein?
Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
What are the official names of this protein?
Xaa-Pro dipeptidyl-peptidase, X-Pro dipeptidyl-peptidase, X-prolyl-dipeptidyl aminopeptidase, X-PDAP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPCKG_HYPBU
Sequence: MYHLFHSRLCLPQGLRSLLAQRMPAAKLLPNDSAVAAYARHRRVVAVGDRVSETLIRHGVKPWVMVFDCVEARRDKTCPSIPEGYAILRTRNERSTVEPGAVEVIRKALRQGHTVVRVDGEEDLLALPALLYGDVGSVVLYGLPGKGVVAAAVNREAKLLAMRVLEFFEPC
What is the function of this protein?
Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
What are the official names of this protein?
GTP-dependent dephospho-CoA kinase, Dephospho-coenzyme A kinase, DPCK.
What is the protein family that this protein belongs to?
Belongs to the GTP-dependent DPCK family.
Protein: NQO3_PARDE
Sequence: MADLRKIKIDDTIIEVDPNMTLIQACEMAGIEVPRFCYHERLSIAGNCRMCLVEVVGGPPKPAASCAMQVKDLRPGPEGAPSEIRTNSPMVKKAREGVMEFLLINHPLDCPICDQGGECDLQDQAMAYGVDFSRYREPKRATEDLNLGPLVETHMTRCISCTRCVRFTTEVAGITQMGQTGRGEDSEITSYLNQTLESNMQGNIIDLCPVGALVSKPYAFTARPWELTKTESIDVMDALGSSIRIDTKGREVMRILPRNHDGVNEEWISDKTRFVWDGLRRQRLDRPYIRENGRLRPASWPEALEAAARAMKGKKIAGLIGDLVPAEAAFSLKQLVEGLGGKVECRVDGARLPAGNRSAYVGTARIEDIDDAEMIQLIGTNPRDEAPVLNARIRKAWSKGAKVGLVGEPVDLTYDYAHVGTDRAALESLSSREISDETKARPSIVIVGQGAIARRDGEAVLAHAMKLAENSNSGLLILHTAAGRVGAMDVGAVTEGGLLAAIDGAEVVYNLGADEVDIDQGPFVIYQGSHGDRGAHRDIILPGACYTEESGLFVNTEGRPQLAMRANFAPGEGKENWAILRALSAELGATQPWDSLAGLRRKLVEAVPHLAQIDQVPQNEWQPLGRFDLGQASFRYAIRDFYLTNPIARSSPLMGELSAMAAARKAPAPLAAE
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase chain 3, NADH dehydrogenase I, chain 3, NDH-1, chain 3.
What is the protein family that this protein belongs to?
Belongs to the complex I 75 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: STAR_CHICK
Sequence: MLPATFKLCAAISYQHLRNVTGLRRQAAVAISQELSKLSCRSTGPSTWISQVRRRSSLLSSRLEEKPFSEMEMSYIKQGEEALQKSLSILGDQEGWKTETVADNGDKVLSKVLPDVGKVFRLEVVVDQPLDAVYSELVDNMEQMGDWNPSVKEVKILQRVGKDTLITHETAAAPPGNIVGPRDFVSVRCSRRRGSTCVLAGMSTTHGAMPEQQGFIRAENGPTCMVLRPLAGSPSQTKLTWLLSIDLKGWLPKTIINQVLSQTQVDFAKHLRQRMARAAGC
What is the function of this protein?
Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone.  Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone (By similarity).
What are the official names of this protein?
Steroidogenic acute regulatory protein, mitochondrial, StAR, START domain-containing protein 1, StARD1.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: L_SV41
Sequence: MAASADILLPEVHLNSPIVKHKLVYFLLLGKLPHNLSEDEITPLHNQNWDQIAHEESNLSERLFAVRSELTRRIAQLRATRWRSEIAVLLWPNSLPYLCTFKPYNRLNTIDEWNKLVSAASNILSSPLSKCMQDISTKLIGRTNLFSRSQSRPGQSADNTITLNKIAAVWADNKWQPLVSLWLTIKYQMRQMIANQSKRTCSELVYVVDTRSGIIIITPELVTCFDKDHSVLMYFTFEMVLMISDLFEGRMNVTALCTVSNYLSPLLSRIERLFDIVDHLAHLLGDNVYKIIASLESLVYGCLQLHDPVIDLAGTFYSFVAQEIVDGLQQGNILSPEEAYTVTEQLLECFSGLSPDLTAELLCLMRLWGHPNLTAAQAAKKVRDTMCAGKVLDFQIIMKTLAFFHTILINGYRRKKNGIWPPLSLPGNASKSLIELHHDNSEISYEYTLRHWKELSLIEFKKCFDFDPGEELSIFMKDKAISAPKEDWMSVFRKSLIKQRHQRHHIPMPNPFNRRLLLNFIEDPSFDPAKELEYVTSGEYLRDPHFCASYSLKEKEIKPDGRIFAKLTNRMRSCQVIAEALLANHAGKLMKENGVVMNQISLTKSLLTMSQIGLISEKAQRYTRDNIALGALFSKGQRTRAHPQTQLSSIDSSQNRELPDDSLELSACFITTDLTKYCPQWRYQTIIPFAKTLNRMYGVPHLFEWIHLRLLRSTLYVGDPFNPPADTSVFDLDQVLNGDIFIVSPKGGIEGLCQKMWTMISISVIILSSAESKTRVMSMVQGDNQAIAVTTKVPRSVPLTEKRNLAYNASKLFFDRLKHNNFGLGHQLKAQETIISSQFFIYSKRVFYQGRILTQALKNASKLCLTADVLGECTQASCSNAATTIMRLTENGVEKDVCYMLNVYQAIRQLCFDLYYPQYSIPGEQISQHYLKHPSIVARLVILPSQLGGLNYLSCSRLFNRNIGDPLGTAVADLKRLIKCGALESWVLSNLLSRKPGTGSWATLAADPYSLNIDYLYPPTTILKRHTQNTLMEVCKNPMLKGVFTDNAREEENNLAKFLLDRDIVLPRVAHIVIEQSSVGRKKQIQGFFDTTRTIMRKSFEIKPLSSKRTLSVIECNINYLAYNFNIIHHPNPIPGYLQCITTDNCSVDIARSLRKLSWSSLLNGRTLEGLETPDPIEVVNGALVIGVGECDYCMQGDTKFTWFFLPKGIEIDGDPEKNPPIRVPYVGSKTEERRVASMAYVKGATSSLKAALRGAGVFIWAYGDTDANWDDALDLANTRVQISKEQLQALTPLPTSANITHRLDDGATTIKFTPASSYAFSSYTHISNDQQYLEVDNRVVDSNIIYQQLMITGLGIIETYNNPPIRTSSEELTLHLHTSSSCCIRPVDGCIICESPSLLPQLTVPYTNPFVYDPNPLADYEIAHLDYLSYQARIGSIEHYSLQDRIDLLAHLTAKQMINSIIGLDESVSLLNDAVVTSDYTNNWISECSYTKIDLVFKMMAWNLLLELSFQMYYLRITTWSNIFDYTYMTLRRIPGNALTNIAATISHPKLLRRAMNLDVITPVHAPYLASLDYIKLSIDAIQWGIKQVLADLHNGIDYEILILSEDSLELSDRAMNLIARKLTLLALIQGNQLVLPKIKGLSPDEKCLVLTEHLMSEYQLLLLDDAELSKRSYNLTNPRITAFPSNNFYLTRKVLNSIRDSEEGQYLIGAYYDSFQQMETDIILHSTLIAPYDTSETLTKFDLCISLFPHDDNLEKYPLPVDHDSQSAVSTIVPGPPIHHVLRPLGVSSTSWYKGLSYVRYLELCKVPTGDHLYLAEGSGASMSLVEMLIPGQKVYYNSLFSSGENPPQRNYAPLPTQFVQSVPYKLWQADLTNKEGIIEDFIPLWNGNGAVTDLSNKDCVAFIIHKVGAEQASLVHVDLESTANLNQQSLSRSQIHALIIATTVLKRGGFLVYKTSWLPFSRLSQLACVLWSFFDKITMIRSSYSDPNSHEIYLVCRLAADFKTIGFSAALASAIAIAIHGDGFTTIHPDVVSNYWQHHLENVGRVGKAIDDVIDGVSTNFYSGDNGLILRCGGTPSSRKWLDIDLLPTFSSLQETLVNLVTVHLKEIIEIQTSSMEDYTSLLFTPYNIGSVGKIRTIVKLILERSLMYVIRNWLVMPSSYQDSVRQDLELGSFRLSSVLQEDTFWKLTENRKYLASQLTRDYITTFFTTHSILPIHRSYQKRIWKALGSVIYCSEVPGESQQNWDSIPLVYEEDQIERGIDGEEL
What is the function of this protein?
RNA-directed RNA polymerase that catalyzes the replication of viral genomic RNA.  The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N).  The replicase mode is dependent on intracellular N protein concentration.  In this mode, the polymerase replicates the whole viral genome without recognizing transcriptional signals, and the replicated genome is not caped or polyadenylated.
What are the official names of this protein?
RNA-directed RNA polymerase L, Protein L, Large structural protein, Replicase, Transcriptase.
What is the protein family that this protein belongs to?
Belongs to the paramyxovirus L protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: NTAL_RAT
Sequence: MNAELELLWPLSGLLLLLLLGTTAWLCVQCSRPGVKRNEKIYEQRNQQENEQSVASSQTYSLARPVRTGLQMDAASNKSFERKNKLLFSHLEGPESPRYQNFYKGSRRESDAAYVDPIPTDYYNWGCFQKPPEDNDSNSYENVLICKPSTPESGTEESEDYQNSVSILQWRESKRTMGARTSPSGSPDEEPDYVNGDVATTEKI
What is the function of this protein?
Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells.  May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells.  Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2 (By similarity).
What are the official names of this protein?
Linker for activation of T-cells family member 2, Linker for activation of B-cells, Non-T-cell activation linker.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type III membrane protein. Note=Present in lipid rafts.
Protein: YIDC_STRCO
Sequence: MDTIASLFSFITWPVSWVIVQFHTVYGAIFGPDTGWAWGLSIVSLVILIRICLIPLFVKQIKATRGMQTLQPEMKKIQERYKNDKQRQSEEMMKLYKETGTNPLSSCLPILAQSPFFFALYHVLNGIASGDTIGKINQPLLESAQKAHIFGAPLAAKFTDGASKVESLGASLTDVRVITAVMIVLMSASQFFTQRQLMTKNVDTSVKTPFMQQQKMLMYVFPVMFAVFGINFPVGVLVYWLTTNVWTMGQQMYVIRNNPTPGSKAQASYLERLHKSVTEHGRTRRRGEKAIVKAIVAKGRDRNEAERKFINGLNKAGLAAQADGNVVKNDAAVAVQSEDGSTVTTTAQPKRQQPKRQSKSQRQAKPAGETEPKTSLTKSDEPQDAEPAGKQDAKPAAGAKKPAQKSGGGGRSKAQSGQRKGPQRPKSPSKK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins (By similarity).
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GPDA_SYNR3
Sequence: MALTIGVLGGGAWGSTLAGLLSQGGHRVQIWRREHGPQALQALAASEVLVGATALVGVSGMAQQIKGWSARPIVSCSKGLDPSSGQTASALWKAACPLWPVVVLSGPNLASELQQGLPAASVLAGHDEGLLSTLQQQLSTEQFRLYRNNDPLGTELAGALKNVMAVAAGICDGLQLGANARASLLTRALAEMATVLHGLGGRQDTLYGLAGIGDLLATATSPLSRNYRFGLCMADGLDRQQALEKVGATVEGVPTCEAIASLGRQKQWSLPITESVALLLQGALSPAQALQQLMQRELRCE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCD_THERP
Sequence: MILSDRDIIAALKSGRIKITPEPDLETQLGACSIDLHLGNTFMVFEHSRFSYIDPRQPQSIGDAMRTIVVPDGEPFIMQAGDFALASTREYIELADDLVGRLEGRSSIARLGITVHSTAALFEPGWAGTATMELSNLGRMAVALYPGMRICSFTFEQLSSPAMVPYRMKRGNKYAGQKDPKPSRLAEELSLEQLRGR
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: ALGI_PSEPK
Sequence: MVFSSNVFLFLFLPIFLGLYYLSGQRYRNLLLLVASYIFYAWWRVDFLALFAGVTLWNYWIGLKVGAAGVRTKPAQRWLLLGVGVDLAILGYFKYANFGVDSLNAIMTSFGLEPFILTHVLLPIGISFYIFESISYIIDVYRGDTPATRNLIDFAAFVAIFPHLIAGPVLRFKDLVDQFNNRTHTLDKFSEGCTRFMQGFIKKVFIADTLAVVADHCFALQNPTTGDAWLGALAYTAQLYFDFSGYSDMAIGLGLMMGFRFMENFKQPYISQSITEFWRRWHISLSTWLRDYLYITLGGNRKGTFNTYRNLFLTMLLGGLWHGANFTYIIWGAWHGMWLAIERALGLDTNPQRFNPVKWAFTFLLVVVGWVIFRAENLHVAARMYGAMFSFGDWQLSELNRAQLTGLQVATLVIAYLTLAFFGLRDFYRNARPTPKATPVQVNADGSIGLDWTRVMTRALILLLFVASILKLSAQSYSPFLYFQF
What is the function of this protein?
Together with AlgJ and AlgF, forms an inner membrane complex which probably interacts with the alginate polymerization-transport complex and adds acetyl groups at the O-2 and O-3 positions of mannuronate residues.  Acetylation of alginate is important for the architecture of biofilms and increases the ability of alginate to act as a defense barrier (By similarity).
What are the official names of this protein?
Probable alginate O-acetylase AlgI, Alginate biosynthesis protein AlgI.
What is the protein family that this protein belongs to?
Belongs to the membrane-bound acyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GALT_STRTR
Sequence: MAENLVNTFVTQVIENSDYEELDRIYLTNKVFTLVGEGVADIETDSSELIDLKDQLLQAGVKAGSVGELKEEQDIIGAQLMDLITPRPSVVNRNFWDTYKSNPEQAIADFYAQSKRNDYVKVKAIAQNIAYKAPTKYGDLEITINLSKPEKDPKAIAAAKNAVASDYPKCQLCMENEGYLGRINHPARSNHRVVRFQMEDKEWGFQYSPYAYFNEHSIFFYGKHEPMHISPLTFGRLLTIVEVFPGYFAGSNADLPIVGGSILTHEHYQGGRHTFPMEVAGIKEKVSFDGYSDVEAGIVNWPMSVLRLRSEDKGRLIALATKILNCWRGYSDEKAGVLAESDGQPHHTITPIARRKDGKFELDLVLRDNQTSEEYPDGIYHPHKDVQHIKKENIGLIEVMGLAILPPRLKTELKDVEDYLLGQGNQVAPIHQEWADELKAQNPNITAEEVTEVVRQSVADIFARVLEDAGVYKTNSEGLAQFKAFVDFVNLAD
What are the official names of this protein?
Galactose-1-phosphate uridylyltransferase, Gal-1-P uridylyltransferase, UDP-glucose--hexose-1-phosphate uridylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMKL_HAEIN
Sequence: MKQLFATTSRGFEELLKVELTELGAQEAKVVQGGVHYQADDETLYRTLLWSRLASRILFPLIETKIYSDLDLYAAVSGFNWLAQFDERVTFFVDFNGTNQEIRHTQFGAMRVKDGIVDYFERQGKTRPDVDKIQPDVRIHAYLNRENLVISLDLSGEALHLRGYREDAGQAPLRETLAAAIVMRSGWQVGSPLVDPMCGSGTLLIEAAQMEAKIAPQLYRLHWGFDFWKAHNQSAWEKVKNEAIELAEEKQREIQPHFYGFDLDHRVLKKAQKNAQNAGVSHLIKWQQADVAALKNPRLNEVGTVICNPPYGERLGTTPALIALYSVFGQRLKKEFCGWNVSVFSSESTLLDCLRMRASRQFKAKNGPLDCVQKNYQVSERKSDAITDEKELEFNRTSEVAPDFANRLQKNIKKISKWAKQQELDAYRLYDADLPEYNLAVDRYADYIVVQEYAAPKNIDENKARQRLLDAVTATLQVTGVETNKLILKVRQKQKGTNQYEKLANKGEYFYVNEYGTQLWVNLTDYLDTGLFLDHRLTRKMIGELAKGKDFLNLFAYTGSATVHAALGGAKSTTTVDMSNTYLNWAEQNLILNDIEGKQHKLIQADCLQWLEKCDRQFDLIFADPPTFSNSKRMEESWDVQRDHVKLMRNLKRVLSNNGTIVFSNNKRGFKMNLVALEELGLSAIEISHKTLPLDFERNKQIHNCWMIQHI
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGMI_AERPE
Sequence: MEDLYLSWPKWFSEALARYSSLEGALEGVEEIYYCGMGGSGAAGDYIEALLSIYAPQGPEFRVVKDFRPPRPPRHRGYGLVLASYSGNTLETVECGSLLSPAAGRVVAVTSGGRLLEMAKERGWLVARLPGGILPRVSFPWMLAASTAMLSGALGVDLEALKRLAGGLDTQGLKGEAERLAGFISRYRIASLVTCGPGIPLAVRLKNELAENAKMPSRLEIYPESSHNDIVALEAAEGLYGAVFIWIEHEGSLCPAVLDVVEGIYREYGVDTISIESSARGGPNATVAEYLSRTLVFGLASVRLALMRGFNPEETPPIDKYKRRLGEALRSQA
What is the function of this protein?
Catalyzes the isomerization of both glucose 6-phosphate and epimeric mannose 6-phosphate at a similar catalytic efficiency.
What are the official names of this protein?
Bifunctional phosphoglucose/phosphomannose isomerase, Glucose-6-phosphate isomerase, GPI, Mannose-6-phosphate isomerase, Phosphoglucose isomerase, PGI, Phosphomannose isomerase, PMI.
What is the protein family that this protein belongs to?
Belongs to the PGI/PMI family.