PharMolix/UniProtQA huggingface dataset:
Protein: H2A_SEPOF
Sequence: MSGRGKGGKVKGKSKTRSSRAGLQFPVGRIHRLLRKGNYAQRVGAGAPVYLAAVMEYLAAEVLELAGNAARDNKKSRIIPRHLQLAIRNDEELNKLLSGVTIAQGGVLPNIQAVLLPKKTQKAAK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: DMTA2_DANRE
Sequence: MDLRPEIPPASQAGSQVHPGAAAAAAAAASIPVSMAGSLLRAPPLLLRATEKYPRTPKCARCRNHGVVSALKGHKRYCRWKDCMCAKCTLIAERQRVMAAQVALRRQQAQEENEARELQLLYGTAEGLALAAANGIIPPRQNYEVFGPVSNESNSGESNIQKFELFPKTPLPGTVTPHQAAGKSVSTDTESVPGMSSPDMRHGSGSENGDRESIVSSPIAKPLKDGEETPGSISPIGSDSGSDTDKDEQEPSPSSAASRQMNAIDILTRVFPNHKRSVLELVLQGCGKNVVQAIEQILNNSGQAKGPEETWTAERMLQSVQPTMSSTPRPMLPGTMTLSNRSAFSPLQPNAPHFGSDPSTYPLSTHLGLNPLRLAYSAHSRGLAFMAPYSTTGLMPTLGFRPPMDYAFSDLIRDRTLLHKDQSYTNGLYGPLVNNTQEKQ
What is the function of this protein?
May be involved in sexual development.
What are the official names of this protein?
Doublesex- and mab-3-related transcription factor A2, Doublesex- and mab-3-related transcription factor 5.
What is the protein family that this protein belongs to?
Belongs to the DMRT family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PDXS_BACC0
Sequence: MTNVTGTERVKRGMAEMQKGGVIMDVINAEQAKIAEEAGAVAVMALERVPADIRAAGGVSRMADPTIVEEVMGAVSIPVMAKCRIGHLVEARVLESLGVDYIDESEVLTPADEVYHLNKRDYTVPFVCGCRDIGEAARRIAEGASMLRTKGEPGTGNIVEAVRHMRQVNAEIRQVASLREDELMTYAKNTGAPYEVLLEIKRLGRLPVVNFAAGGVATPADAALMMQLGADGVFVGSGIFKSENPAKFARAIVEATTHYEDYELIASLSKGLGNAMKGIEISTLLPEQRMQERGW
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: CCR5_CERNS
Sequence: MDYQVSSPTYDIDYYTSEPCQKINVKQIAARLLPLLYSLVFIFGFVGNILVVLILINCKRLKSMTDIYLLNLAISDLLFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWVVAVFASLPRIIFTRSQREGLHYTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVMLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTQCCINPIIYAFVGEKFRNYLLVFFQKHIAKRFCKCCSIFQQEVPERASSVYTRSTGEQEIFVGL
What is the function of this protein?
Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level.  May play a role in the control of granulocytic lineage proliferation or differentiation.  Participates in T-lymphocyte migration to the infection site by acting as a chemotactic receptor.
What are the official names of this protein?
C-C chemokine receptor type 5, C-C CKR-5, CC-CKR-5, CCR-5, CCR5.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MNMA_ACIAD
Sequence: MQQRVIVGMSGGVDSSVSAALLLQQGYQVEGLFMKNWEEDDGTEYCTALEDLADAQAVADKIGIKLHTANFAMEYWDRVFEHFLAEYAAGRTPNPDILCNKEIKFRAFIDHAMTLGADFIATGHYTRRGESMQNSRGESYAPLLRGVDNNKDQSYFLHAVHGREINKTLFPVGEIEKPEVRKIAEKLDLATAKKKDSTGICFIGERRFNDFLKQYLPAQPGKIVLDNGKEVGEHHGLMYYTLGQRGGIGLGGLKGAAEGAWFVLHKDLENNRLVIGQGHEHPLMQSTTLWSQDIDWVAGEQDIPASGFRCTAKTRYRQPDQACTIYRDEDRNNGVRVEFDEPQRAVTPGQSVVFYTNEICLGGGVILHTDAPTPDFI
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQRE_ALCBS
Sequence: MFEHYLSLFVRAVFVENMALAFFLGMCTFIAISKKIQTAIGLGIAVVVVLAITVPVNNLILHNLLEEGALSWTGSEQLASLDLRFLGLLSYIGVIAAIVQILEMTLDKYVPSLYNALGIFLPLITVNCAIMGASLFMVERDYTFGESVVYGVGAGVGWALAITLLAGIREKLKYSDVPDGLKGLGITFITVGLMSLGFMSFSGVQL
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit E, Na(+)-NQR subunit E, Na(+)-translocating NQR subunit E, NQR complex subunit E, NQR-1 subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SPNDC_MOUSE
Sequence: MALKAKGAAALDCFEVTLKCEEGDDDDEAVVVAVIPRPEPMLRVTQQEKTPPPRPNLLEAGVEGCEELKQQVSWEQEFLVGNSPGGSGRALCMVCGAEIRSPSADTARAHILEQHPHTLDLSPSEKSNILEAWSEGVALLQDIQADQPSLPSLESGQDGQPDPISNPDPVRMPAEIVVLLDSEDNPSLPKRLRPRGLRPLELPVTPVIEQGNKKPRGQRWKESPENEPARKKRSRHMTKILDPDPDPPSPESPTETFAAPAEVRHFTDGSFPPGFVLQLFSHTQLRTTDCKDSSKDSRAAEGLPQPQNPSSASPPGLRGTLDLQVIRVRMEEPPAVSLLQDWSKHPQGTKGVGTGDKPDWPTVLSESSATVKGQPKAGSGV
What is the function of this protein?
Negatively regulates the transcriptional activator activity of SPIN1 via inhibition of its histone methyl-binding ability (PubMed:29061846).  Represses the expression of a number of SPIN1-regulated genes and the SPIN1-mediated activation of the Wnt signaling pathway (PubMed:29061846).  Can also inhibit the histone methyl-binding abilities of SPIN2A, SPIN2B, SPIN3 and SPIN4 (By similarity).  Positively regulates poly-ADP-ribosylation in response to DNA damage; acts by facilitating PARP1 ADP-ribosyltransferase activity (PubMed:34737271).
What are the official names of this protein?
Spindlin interactor and repressor of chromatin-binding protein, SPIN1-docking protein, SPIN-DOC.
Protein: DNAK_CLAM3
Sequence: MARAVGIDLGTTNSVVSVLEGGEPTVIANAEGARTTPSVVAFTKDGEVLVGETAKRQNVTNVDRTISSVKRHMGTDWTVGIDDKKYTSQELSARILGKLKRDAEQYLGDSVTDAVITVPAYFNDAERQATKEAGEIAGLNVLRIINEPTAAALAYGLDRGKEDELILVFDLGGGTFDVSLLEVGKDDDFSTIQVRSTAGDNRLGGDDWDQRIVDHLVKRFKESTGVDVSNDKIAKQRLKEAAEQAKKELSSSTSTSIQLPYLSLTENGPANLDETLTRAKFEELTNDLLERTRKPFEDVIREAGVSVGDVAHVVLVGGSTRMPAVVDLVKKLTGGKEPNKGVNPDEVVAVGAALQAGVLKGERKDVLLIDVTPLSLGIETKGGIMTKLIERNTAIPTKRSETFTTADDNQPSVAIQVFQGEREFTRDNKNLGTFELTGIAPAPRGIPQVEVTFDIDANGIVHVSAKDKGTGKEQSMTITGGSSLGKEDIERMVREAEEHAAEDKTRREQAEVRNNAEQLAYSIDKLIKENDDKLPEDVKSEVQGDVDGLKSALAGDDEDAVKTAFDKLSASQTKLGEAIYAQGQQEQAAGETPEGASEAKKDDEDIVDAEVVDEDDEDKKTDR
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: TLCD4_MOUSE
Sequence: MEASTKAAVGSGAMEASTKAVICTVCSSFVVFQILFHFVSYWFSARVSSGYNSLSIDKKIEWNSRVVSTCHSLLVGIFGLYLFFFDEATITDPLWGDPTYVNINIATASGYLISDLLIILFNWKVIGDKFFIIHHCAGLTAYYFVLTTGALAYIANFRLLAELSSPFVNQRWFFEALKYPKFSKANVINGILMTVVFFIVRIISIPPMYFFLYSVYGTEPYIRFGFVIQSVWIVTCVILDVMNIMWMIKITKGCIKVISLIRQEKAKDSLQNGKLD
What are the official names of this protein?
TLC domain-containing protein 4, Transmembrane protein 56.
What is the protein family that this protein belongs to?
Belongs to the TLCD4 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CSN_ASPOR
Sequence: MHFAGIVAIALATGATAYDLPENLKQIYEKHKSGKCSKELQGGYDNGHSHDGKSFSYCGDIPNAIYLHSSKNGGQYADMDIDCDGANRHAGKCSNDHSGQGETRWKDEVQKLGIDDLDANIHPYVVFGNENDDGDDPEFDPRKHGMEPLSVMAVVCNKKLFYGIWGDTNGHTATGEASLSMAELCFPEEDPSGDSGHEPNDVLYIGFTGKEAVPGKSADWKADSTESFEESIKELGDKLVAGLKA
What is the function of this protein?
Chitosanase catalyzing the endo-type cleavage of chitosan, the deacylated form of chitin.  Chitosanase may be crucial in the degradation of the deacetylated portion of chitin in the fungal cell wall.  Chitoolisaccharides produced by the hydrolysis of partially N-acetylated chitosan are known to have many biological activities, including antibacterial activity, immune-enhancing effects, and elicitor activity.
What are the official names of this protein?
Endo-chitosanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 75 family.
What are the subcellular locations of this protein?
Secreted.
Protein: DDX1_DROVI
Sequence: DDEADRLLKQGYTDLIERLHKQIPKITSDGCRLQMIVCSATLHAFEVKKMAERLMHFPTWGDLKGEDAVPETVHHVVCMVDPHTDSSWQQLRQPIHTDGVHDHDNVHPTNQSPETFSQAVKLLKGEYCIRAIDQHKMDRAIIFCRTKQDCDNLEQHLSQRGGQRFSCVCLHGDRKPQERKQNLEMFKRQEVKFLICTDVAARGLDITGLPFSKDLKYLSENTLNFPNLAVINITLPDDKSNYVHRIGRVGRPESMGLAISLVSTVPEKVWYHGEWCKTRGRSGSCIWYNEPNLLAEVEDHLNITIQQVVKSLDVPVNDFDGKVVYGQKNLNMGTGYEDHVEQLGPTVRKQTDLELQSQSLFLKRLKRLNWFDFGLLHDPKYFHGYEYIKYINKLTLKSCV
What is the function of this protein?
Acts as an ATP-dependent RNA helicase, able to unwind both RNA-RNA and RNA-DNA duplexes.  Possesses 5' single-stranded RNA overhang nuclease activity (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase Ddx1, DEAD box protein 1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX1 subfamily.
Protein: RPOZ_CLOBM
Sequence: MSNSMINPSIVNLLEKVDDRYSLVTITSKRSRQLIDGAKSLVDIDSTKPVTVAINEIHEGKITYKTVKEGIK
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: HOATZ_MOUSE
Sequence: METGPRGCPSGRKESQEICSPGLLVFTGCSEQDANLAKQFWLGASMYPTTESQLVLTRGSSQRLPVARNSKVVLREKSSVQPFPFDQDKDAIIFAKAQRIQESEERAKYLQKAKTRDEILQLLRKQREERISKELISLPYKPKDKVPKSKEVLSESGLRDQEEVKALE
What is the function of this protein?
Required for motile ciliogenesis and flagellar genesis by mediating the maturation of the glycolytic enzyme ENO4.
What are the official names of this protein?
Cilia- and flagella-associated protein HOATZ.
What is the protein family that this protein belongs to?
Belongs to the HOATZ family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, cilium.
Protein: RNH2_BLOFL
Sequence: MCTRKYFLSKKATIVAGVDEVGCGSLVGAVVASAVLMLYPDQEQLFSGLIDSKALSNKKRLRFCNYIQKYSLHWSIGMVNVTEIDQLNIFQARLLSIKRAICNLSMIPDLVLIDGKHAPSLNKNILYQCFVKGDSRIPVISAASIIAKVTRDQAMMMLHTQYPKYGFHRNKGYATVFHLKQLDLYGPTIYHRKTFAPVKYMLSMC
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NS1_I75A0
Sequence: MDSNTVSSFQVDCFLWHVRKQIVDQELGDAPFLDRLRRDQKSLRGRGSTLGLDIEAATHVGKQIVEKILKEESDEALTMTMASTPASRYITDMTTEELSRDWFMLMPKQKVEGPLCIRIDQAIMDKNIMLKANFSVIFDRLETLISLRAFTEEGAIVGEISPLPSFPGHTIEDVKNAIGVLIGGLEWNDNTVRVSKTLQRFAWGSSNENGGPPLTPKQKRKMARTARSKVRRDKMAD
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: OPS1_CALVI
Sequence: MERYSTPLIGPSFAALTNGSVTDKVTPDMAHLVHPYWNQFPAMEPKWAKFLAAYMVLIATISWCGNGVVIYIFSTTKSLRTPANLLVINLAISDFGIMITNTPMMGINLFYETWVLGPLMCDIYGGLGSAFGCSSILSMCMISLDRYNVIVKGMAGQPMTIKLAIMKIALIWFMASIWTLAPVFGWSRYVPEGNLTSCGIDYLERDWNPRSYLIFYSIFVYYLPLFLICYSYWFIIAAVSAHEKAMREQAKKMNVKSLRSSEDADKSAEGKLAKVALVTISLWFMAWTPYTIINTLGLFKYEGLTPLNTIWGACFAKSAACYNPIVYGISHPKYGIALKEKCPCCVFGKVDDGKASDATSQATNNESETKA
What is the function of this protein?
Visual pigments are the light-absorbing molecules that mediate vision.  They consist of an apoprotein, opsin, covalently linked to cis-retinal.
What are the official names of this protein?
Opsin Rh1, Outer R1-R6 photoreceptor cells opsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RLMH_LIGS1
Sequence: MNIKIIGVGKLKEKYLKQGIAEYAKRLGTFCKFQIVEVPDEKAPEKLSPAEMEGVKEKEGERILAKIKDKEYVYALAIEGKERSSEEFAKELEDLGTYGTSDITFVIGGSLGLSPEVLKRANTKISFGRFTLPHQLMRMVLAEQIYRGFMINAGRPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_CHLP8
Sequence: MSPTFFIHTFGCQMNMADTEIVTAILVEGGFAPAEDEGTADMVLLNTCAVRANAVDRAGNVLSHLKGMKRRRKGLVVGLLGCVPQYEREQLFGDFPFVDFIVGPDNYRDLCGIVRSVREGEQRRAFIDYDQQETYAGIDPIRANRVSTFLPVMRGCNNHCAFCVVPVTRGRERSVAFDRVIAEVAALEQAGYREVTLLGQNVNSWCDADKSLDFAGLLEGVSHAAPSMRIRFTTSHPKDISESLVRVIGERPNLCKHIHLPVQSGSSRMLDLMKRGHTREEYLDKIAMIRELVPGVAITTDLIAGFCTETEVDHRETLSLMEAVGYDTAFMFYYSVRPGTWAARNLPDDVPEAVKKARLQEIIDLQTAMSRELYQREIGKVVEVLAEAESKRSASQLMGRTSENRAVVFSREHFMPGDLVPVRITAATSATLSGEALVQPSNP
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMB_ECOLI
Sequence: MKNDVISPEFDENGRPLRRIRSFVRRQGRLTKGQEHALENYWPVMGVEFSEDMLDFPALFGREAPVTLEIGFGMGASLVAMAKDRPEQDFLGIEVHSPGVGACLASAHEEGLSNLRVMCHDAVEVLHKMIPDNSLRMVQLFFPDPWHKARHNKRRIVQVPFAELVKSKLQLGGVFHMATDWEPYAEHMLEVMSSIDGYKNLSESNDYVPRPASRPVTKFEQRGHRLGHGVWDLMFERVK
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: METE_STRPN
Sequence: MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAKHWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQGEKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVGPFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEKALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVKGGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEEFEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAGLTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKEYDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGMRGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKDSTLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVHSTVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEANRSNLEILDELKAKNFQTEVGPGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVEAAKAAREKL
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: RL14_CHLP8
Sequence: MIQKETNLVVADNSGAKKVRCIHVFGGTGRRYAALGDQIMVTVKAAVPNGVVKKKDVCKAVVVRCAKEQRRKDGSYIRFDENAVVLLNAQGEPRGTRIFGPVARELRDKRYMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RPOC2_MANES
Sequence: MEVLMAERANLVFHNKAIDGTAIKRLISRLIDHFGMAYTSHILDQVKTLGFQQATATSISLGIDDLLTIPSKGWLVQDAEQQSLILEKHYHYGNVHAVEKLRQSIEIWYATSEYLRQEMNLNFRMTEPFNPVHIMSFSGARGNTSQVHQLVGMRGLMSDPQGQMIDLPIQSNLREGLSLTEYIISCYGARKGVVDTAVRTSDAGYLTRRLVEVVQHIVVRRTDCGTARGISVSPRNGMMPERIFIQTFIGRVLADNIYMGLRCIAIRNQDIGIGLANRFITFRTQTISIRTPFTCRSTSWICRLCYGRSPTHGDLVELGEAVGIIAGQSIGEPGTQLTLRTFHTGGVFTGGTAEHVRAPSNGKIKFNEDLVHPIRTRHGHPAFLCYIDLYVTIKSQDIIHNVTIPPKSFLLVQNDQYVESEQVIAEIRAGAYTLNFKEKVRKHIYSDSEGEMHWSTDVYHAPEFTYSNVHLLPKTSHLWILSGSSCRSSIVPFSLHKDQDQMNVHSLSVKRRYISSPSVNNDQVKHKFFSSDFSGKKESGIPDYSELNRSICTGHCNLIYSTILYKNSDLLAKRRRNKFIIPFQSIQEREKELMTQSAISIEIPINGIFRRNSVFAYFDDPQYRKKSSGITKYGAIGVHSIVKKEDLIEYRGVKEFKPKYQTKVDRFFFIPEEVYILPESSSLMVRNNSIIGVDTQIALNTRSRVGGLVRVERKKKKMELKIFSGDIHFPGETDKISRHSDILIPPGTVKTNSKESKKVKNWIYIQRITPTKKKYFVLVRPVIIYEIANGINLETLFPQDLLQEKDNLKLRVVNYILYGTGKPIRGISDTSIQLVRTCLVLNWDQDKKSSSIEEARAAFVEISTNGLIRDFLRINLVKFHISYIGRKRNDPSGSEPISNNGSDRTNINPFYPIYSKTRVQQSLKQNQGTISTLLNINKECQSLIILSSSNCFQMDPFNDVKHHNVIKESIKRDPIIPIRNSLGPLGTALQIANFYLFYHLNLITHNQISVTKYSKLYNLKQTFQVLKYYLMDENGRIVNPDPCSNSVLNPFNLNWYFLHHNYCESFFTIISLGQFICENLCMAKNGPHLKSGQVIIVHIDSVVIRSAKPYLATPGATVHGHYGEILYEGNTLVTFIYEKSRSGDITQGLPKVEQVLEVRSIDSISINLEKRVEGWNECITRILGIPWGFLIGTELTIVQSRISLVNKIQKVYRSQGVQIHNRHIEIIVRQITSKVLVSEDGMSNVFSPGELIGLLRAERTGRALEEAICYGAILLGITRASLNTQSFISEASFQETTRVLAKAALRGRIDWLKGLKENVVLGGMIPVGTGFKGLVQGSRQHKNIPLKTKKKNLFEGEFRDRDILFHHRELFDSCISKNLYDTSEQSFIGFNDS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta'', PEP, Plastid-encoded RNA polymerase subunit beta'', RNA polymerase subunit beta''.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PRMA_PSEMY
Sequence: MPWLQVRLAITPEQAETFEDALLEVGAVSVTFMDAEDQPIFEPDLGTTPLWSHTHLLALFEADTDETALIAHLQLLCGGTLPEHHVERIEDQDWERSWMDNFQPMRFGQRLWIVPSWHAAPEPDAVNLLLDPGLAFGTGTHPTTALCLEWLDGQNLDGCRVLDFGCGSGILAIAALLLGAPQAVGTDIDPQALEASRDNANRNGIDPARFPVYLPADLPQQPAEVVVANILAGPLVSLAPQITALVQEGGRLALSGILAEQAEEVRAAYAGAFDLDPTAIKDGWVRISGVKR
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_MYCPA
Sequence: MPRKGPAPKRPLVNDPVYGSQLVTQLVNKVLLKGKKSLAERIVYGALENAREKTGTDPVITLKRALDNVKPALEVRSRRVGGATYQVPVEVRPDRSTTLALRWLVSFSRQRREKTMVERLANEILDASNGLGASVKRREDTHKMAEANRAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RS15_ECOBW
Sequence: MSLSTEATAKIVSEFGRDANDTGSTEVQVALLTAQINHLQGHFAEHKKDHHSRRGLLRMVSQRRKLLDYLKRKDVARYTQLIERLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: FLGI_CAMJR
Sequence: MRVLTIFLLFMTSIFAVQIKDVANTVGVRDNQLIGYGLVVGLNGSGDGTSSKFTLQSISNLLQGMNIKVDPNDIKSKNTAAVMVTAKLPAFAKSGDKLDITVSSMGDAKSLQGGTLLLTALRGIDGEIYAIAQGSISTGGLTPRPGGAGSHSTAATVMGGANVEREIPQNFSQNNDLTLSLKVADFKTANDIERVLNTVFGEEVAKAIDSRTVKLKKPEDLSNVDFMARVLEQDIAYKPQSKVIIDERTGTVIAGVDVEVEPVLITHKDITIKIDPNNNAVANQNEIDMKDGGFVDPSSNTLRINNAKSTVANIARMLNKLGATPNDIIAIMENLKRAGAINADLEII
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: Y099_PETMO
Sequence: MYGLINIGFGNIVVGDRVIAIVSPTSQPLKRLKEIAEQQGKLLEVNHGRKTRAFIITDSGHVIASAIQPETITNRFLQNYYDIEKVLDKIRKEVL
What are the official names of this protein?
Putative regulatory protein Pmob_0099.
What is the protein family that this protein belongs to?
Belongs to the RemA family.
Protein: TRAJ8_ECOLX
Sequence: MTVVDPARFMYERNHFPSLTDKEFETLVLYCQMMNVQMVADYQNRKPDVIIKHLKSCRQKIGVESDFELYFIVINKFVNFERVFPELTSEQINILAAFSFYPKRSTIARRFDIYRCDIYDELIKIRNNLGIEDLESLRMLFFMKITVFL
What is the function of this protein?
This protein is essential for positively regulating the expression of transfer genes that are involved in the conjugal transfer of DNA between bacterial cells.
What are the official names of this protein?
Protein TraJ.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.