PharMolix/UniProtQA huggingface dataset:
Protein: LOLD_RHILO
Sequence: MAEVIIELKSVERHYVQGPRKLTILNGADFSLKRGEMVALVAPSGTGKSTLLHTAGLLERPDAGDVILAGRACGRLSDDERTAIRRNDVGFVYQFHHLLPEFSALENIMMPQLIKGLPRKEAAERAAQLLDYMQIGKRASHRPSELSGGEQQRVAIARAVANAPLVLLADEPTGNLDPVTASYVFEALGALVKQSGLAALIATHNHELASRMDRRVTLADGKVVPL
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GUAA_VIBCH
Sequence: MTKNIHDQRILILDFGSQYTQLVARRVREIGVYCELWSWDVEEADIREFNPDGIILSGGPESVTEANSPRAPQYVFDSGVPVFGVCYGMQTMAEQLGGRVATSDEREFGYAQVKISGESALFKDLDLTQDVWMSHGDKVVEIPADFVKIGETDTCPYAAMANEEKKYYGVQFHPEVTHTKNGLQMLENFVLGVCGCERLWTSESIIEDAVARIKEQVGNDEVILGLSGGVDSSVVAMLVHRAIGSKLTCVFVDNGLLRLNEGEQVMEMFGDKFGLNIIKVDAEERFLKALEGIDEPEAKRKTIGRVFVEVFDEESKKLSNAKWLAQGTIYPDVIESAASKTGKAHVIKSHHNVGGLPDDMKMGLVEPLRELFKDEVRKIGLELGLPYNMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELHAADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYEFLGKVSNRIINEVNGISRVVYDISGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: REX_PELTS
Sequence: MKALKVPEATITRLSVYSRFLERMDRNGIVTVSSGEIAEGVGVSSAQVRKDLAYFGEFGTRGVGYNVKDLMHYTSKILGLNEPWPIVLAGAGNLGFALCTYKGFNDRGFTIVGVFDNDLTKIGKKIVDLEVYPPERMPEVIAKHKVRIGIIAVPARAAQEVADQMVKNGLQAILNFAPVVLNVPDHVLLRNVDLSVSLEVLTFNLVQKESQAG
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARND_ECOHS
Sequence: MTKVGLRIDVDTFRGTREGVPRLLEILSKHNIQASIFFSVGPDNMGRHLWRLVKPQFLWKMLRSNAASLYGWDILLAGTAWPGKEIGHANADIIREAAKHHEVGLHAWDHHAWQARSGNWDRQTMIDDIARGLRTLEEIIGQPVTCSAAAGWRADQKVIEAKEAFHLRYNSDCRGAMPFRPLLESGNPGTAQIPVTLPTWDEVIGRDVKAEDFNGWLLNRILRDKGTPVYTIHAEVEGCAYQHNFVDLLKRAAQEGVTFCPLSELLSETLPLGQVVRGNIAGREGWLGCQQIAGSR
What is the function of this protein?
Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
Protein: RNC_STRP3
Sequence: MKQLEELLSTSFDIQFNDLTLLETAFTHTSYANEHRLLNVSHNERLEFLGDAVLQLIISEYLFAKYPKKTEGDMSKLRSMIVREESLAGFSRFCSFDAYIKLGKGEEKSGGRRRDTILGDLFEAFLGALLLDKGIDAVRRFLKQVMIPQVEKGNFERVKDYKTCLQEFLQTKGDVAIDYQVISEKGPAHAKQFEVSIVVNGAVLSKGLGKSKKLAEQDAAKNALAQLSEV
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SH21B_HUMAN
Sequence: MDLPYYHGRLTKQDCETLLLKEGVDGNFLLRDSESIPGVLCLCVSFKNIVYTYRIFREKHGYYRIQTAEGSPKQVFPSLKELISKFEKPNQGMVVHLLKPIKRTSPSLRWRGLKLELETFVNSNSDYVDVLP
What is the function of this protein?
Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as CD84, SLAMF1, LY9 and CD244 (PubMed:11689425).  In SLAM signaling seems to cooperate with SH2D1A/SAP.  Plays a role in regulation of effector functions of natural killer (NK) cells by controlling signal transduction through CD244/2B4 without effecting its tyrosine phosphorylation; downstream signaling involves PLCG1 and ERK activation (PubMed:24687958).  Activation of SLAMF7-mediated NK cell function does not effect receptor tyrosine phosphorylation but distal signaling (By similarity).  In the context of NK cell-mediated cytotoxicity does not enhance conjugate formation with target cells but stimulates polarization of the microtubule-organizing center and cytotoxic granules toward the NK cell synapse (PubMed:24687958).  Negatively regulates CD40-induced cytokine production in dendritic cells downstream of SLAM family receptors probably by inducing activation of the PI3K pathway to inhibit p38 MAPK and JNK activation (By similarity).
What are the official names of this protein?
SH2 domain-containing protein 1B, EWS/FLI1-activated transcript 2, EAT-2.
Protein: PSAB_PHAAO
Sequence: MTLRFPRFSQGLAQDPTTRRIWFGIATAHDFESHDDITEERLYQNIFASHFGQLAIIFLWTSGNLFHVAWQGNFESWIQDPLHVRPIAHAIWDPHFGQPAVEAFTRGGAIGPVNIAYSGVYQWWYTIGLRTNGDLYTGALFLLLLSAISLIASWLHLQPKWKPSVSWFKNAESRLNHHLSGLFGVSSLAWTGHLVHVAIPGSRGEYVRWNNFLEVLPYPQGLGPLFMGQWNLYAQNPDSSNHLFGTSQGAGTAILTLLGGFHPQTQSLWLTDIAHHHLAIAFLFLVAGHMYRTNFGIGHSIKDLLEAHIPPGGRLGRGHKGLYDTINNSLHFQLGLALASLGVITSLVAQHMYSLPAYAFIAQDFTTQAALYTHHQYIAGFIMTGAFAHGAIFFIRDYNPEQNEDNVLARMLDHKEAITSHLSWASLFLGFHTLGLYVHNDVMLAFGTPEKQILIEPIFAQWIQSAHGKTSYGFDVLLSSTNSPAFNAGRSIWLPGWLNAINENSNSLFLTIGPGDFLVHHAIALGLHTTTLILVKGALDARGSKLMPDKKDFGYSFPCDGPGRGGTCDISAWDAFYLAVFWMLNTIGWVTFYWHWKHITLWQGNVSQFNESSTYLMGWLRDYLWLNSSQLINGYNPFGMNSLSVWAWMFLFGHLVWATGFMFLISWRGYWQELIETLAWAHERTPLANLIRWKDKPVALSIVQARLVGLVHFSVGYIFTYAAFLIASTSGKFG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2, PSI-B, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein.
Protein: PNP_BRUSU
Sequence: MFNTHKVEIEWGGRPLTLETGKIARQADGAVLATYGETAVLATVVSAKEPKPGQDFFPLTVNYQEKTYAAGKIPGGYFKREGRPSENETLVSRLIDRPIRPLFVDGYKNDTQVVITVLQHDLENNPDILSMVAASAALTISGVPFMGPISGARVGYIDGEYVLNPNIDEMPESKLDLVVAGTSEAVLMVESEAQELPEDVMLGAVMFGHKSFQPVIDAIIKLAEVAAKEPRDFQPEDLSELEAKVLAVVENDLREAYKITEKQARYAAVDAAKAKAKEHFFPEGVEETEMSAEQFATIFKHLQAKIVRWNILDTGNRIDGRDLSTVRPIVSEVGILPRTHGSALFTRGETQAIVVATLGTGEDEQMIDALTGTYKESFMLHYNFPPYSVGETGRMGSPGRREIGHGKLAWRAIHPMLPAAEQFPYTIRAVSEITESNGSSSMATVCGTSLALMDAGVPIVRPVAGIAMGLIKEGERFAVLSDILGDEDYLGDMDFKVAGTEFGITSLQMDIKIDGITEEIMKVALEQAKGGRVHILGEMAKAISSSRAELGEFAPRIEVMNIPTDKIRDVIGSGGKVIREIVEKTGAKINIEDDGTVKIASSNGKEIEAAKKWIHSIVAEPEVGEIYEGTVVKTADFGAFVNFFGPRDGLVHISQLAADRVAKTTDVVKEGQKVWVKLMGFDERGKVRLSMKVVDQETGKEIVAEKKKEEVDAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_HELHP
Sequence: MFVDSVDIFIASGKGGAGAVSFRREKFVIHGGPDGGDGGDGGDVYVEVDNNTDTLSKFRGARHYKAKNGQPGGSRRCSGKRGNDVVIKVPLGTQILDFDTKELIVDMDTCPMRVCLLKGGKGGLGNTHFKNAANQAPTYAQSGLSGEEKHILLELKLIADVGLVGFPNVGKSTLISTLSNAKPEVANYEFTTLIPHLGVVDADEFSSFVMADIPGIIEGASGGKGLGIAFLKHIERTGFLLFVLDIMREQSLKEQWEILSLELEKFSPILSQRAFGIVLSKSDMQHLGEEFADKFDKQTQELEQFLAQKGNPQSFILPISSIQKSGLKELVFEILNSLRINPQSILQ
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEF_BRADU
Sequence: MTTMAKKSLQLGRAVEWPHTPEEAQLDRVPNPQKGTDYLVRFTVPEFTSLCPVTGQPDFAHLMIDYAPGPWLLESKSLKLYIASFRNHGAFHEDCTVMIGKRIASEIKPKWLRIGGYWYPRGGIPIDVFWQTGRVPKGLWVPEQGVAPYRGRG
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VG23_BPMD2
Sequence: MAENDDAVLTAAVGYVYVAEAGTAAHTPAELKTIDLSDPSTWTGATGWSSVGHTSRGTLPEFGFEGGDSEVKGSWQKKKLREITTEDPIDYVVVLLHQFDEQSLGLYYGPNASTTPGVFGVKTGQTNEKAVLVVIEDGDMRLGHHAHKAGVRRDDAIELPIDDLAALPVRFTYLDHKDELPFSWINEDLFGLSPGGGA
What are the official names of this protein?
Major tail protein Gp23, Major coat protein.
What are the subcellular locations of this protein?
Virion.
Protein: SRG30_CAEEL
Sequence: MLKCHPGFNTKLELLKYGIQFVYFIVGLGFHFAVIKVLHKKWSVYSKYPFLKLYYVDSILSVLIILLDLVLIRVFNYIPPLCQWVLQEFPEPSQLISILFIEQYLQFVKSLIFCFMVVNRANNVICVKSFGTIQSCIIPHVIVFCILCPLLGVWTAFLSDSRFVPFQGGFIHETMMEYHWITVSQFSVIISSITIVTVCICSVISMLCISRTHAENKHTEQSLTASALAMSIFYVFALSMNIYCQKAHASSLEMLEFWKALTAFAFDIILVCPPVIMLCLNVRLRINVFSVDTRPTSPK
What are the official names of this protein?
Serpentine receptor class gamma-30, Protein srg-30.
What is the protein family that this protein belongs to?
Belongs to the nematode receptor-like protein srg family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FMK7_PSEAI
Sequence: DVNGGWSCATTVDAKFRPNGCTD
What are the official names of this protein?
Fimbrial protein, Pilin.
What is the protein family that this protein belongs to?
Belongs to the N-Me-Phe pilin family.
What are the subcellular locations of this protein?
Fimbrium.
Protein: PLSY_PROMM
Sequence: MFNSLFGNLLSLVMGYLLGSLPSGYLAAHWLAGIDLREKGSGSTGATNVLRQVGKGPALAVFLIDVGKGTTAVLVARALELDDGWQVAAGLAALAGHIWPVWLGWKGGKAVATGLGMLLGISWPVGLACFGIFLTVLSFSRIVSLSSIIAALSLPLLMILRFQGNSPPAYLAVAFAAMAMVVWRHRSNLQRLLAGTEPRLGQSS
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CNGB1_BOVIN
Sequence: MLGWVQRVLPQPPGTPQKTKQEEEGTEPEPELEPKPETAPEETELEEVSLPPEEPCVGKEVAAVTLGPQGTQETALTPPTSLQAQVSVAPEAHSSPRGWVLTWLRKGVEKVVPQPAHSSRPSQNIAAGLESPDQQAGAQILGQCGTGGSDEPSEPSRAEDPGPGPWLLRWFEQNLEKMLPQPPKISEGWRDEPTDAALGPEPPGPALEIKPMLQAQESPSLPAPGPPEPEEEPIPEPQPTIQASSLPPPQDSARLMAWILHRLEMALPQPVIRGKGGEQESDAPVTCDVQTISILPGEQEESHLILEEVDPHWEEDEHQEGSTSTSPRTSEAAPADEEKGKVVEQTPRELPRIQEEKEDEEEEKEDGEEEEEEGREKEEEEGEEKEEEEGREKEEEEGEKKEEEGREKEEEEGGEKEDEEGREKEEEEGRGKEEEEGGEKEEEEGRGKEEVEGREEEEDEEEEQDHSVLLDSYLVPQSEEDRSEESETQDQSEVGGAQAQGEVGGAQALSEESETQDQSEVGGAQDQSEVGGAQAQGEVGGAQEQDGVGGAQDQSTSHQELQEEALADSSGVPATEEHPELQVEDADADSRPLIAEENPPSPVQLPLSPAKSDTLAVPGSATGSLRKRLPSQDDEAEELKMLSPAASPVVAWSDPTSPQGTDDQDRATSTASQNSAIINDRLQELVKLFKERTEKVKEKLIDPDVTSDEESPKPSPAKKAPEPAPEVKPAEAGQVEEEHYCEMLCCKFKRRPWKKYQFPQSIDPLTNLMYILWLFFVVLAWNWNCWLIPVRWAFPYQTPDNIHLWLLMDYLCDLIYLLDITVFQMRLQFVRGGDIITDKKEMRNNYVKSQRFKMDMLCLLPLDLLYLKFGVNPLLRLPRCLKYMAFFEFNNRLESILSKAYVYRVIRTTAYLLYSLHLNSCLYYWASAYEGLGSTHWVYDGVGNSYIRCYYWAVKTLITIGGLPDPRTLFEIVFQGLNYFTGVFAFSVMIGQMRDVVGAATAGQTYYRSCMDSTVKYMNFYKIPRSVQNRVKTWYEYTWHSQGMLDESELMVQLPDKMRLDLAIDVNYSIVSKVALFQGCDRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREMYIIQAGQVQVLGGPDGKSVLVTLKAGSVFGEISLLAVGGGNRRTANVVAHGFTNLFILDKKDLNEILVHYPESQKLLRKKARRMLRNNNKPKEKSVLILPPRAGTPKLFNAALAAAGKMGAKGGRGGRLALLRARLKELAALEAAARQQQLLEQAKSSEDAAVGEEGSASPEQPPRPEPPAPEAPAPEPTAPEPLAPEAPAPEAPAPSSPPPASQERPEGDKDAARPEEHPVRIHVTLGPDPSEQILLVEVPEKQEEKEKKEEETEEKEEGEEARKEKEEE
What is the function of this protein?
Subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction.  When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP (By similarity).
What are the official names of this protein?
Cyclic nucleotide-gated cation channel beta-1, 240 kDa protein of rod photoreceptor CNG-channel, Cyclic nucleotide-gated cation channel 4, CNG channel 4, CNG-4, CNG4, Cyclic nucleotide-gated cation channel gamma, Cyclic nucleotide-gated cation channel modulatory subunit, Cyclic nucleotide-gated channel beta-1, CNG channel beta-1, Glutamic acid-rich protein, GARP.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family. CNGB1 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CHEB_PHOLL
Sequence: MNKITVLCVDDSALMRQIMREIINSHSDMEVVACAPDPLVARDLIKKHNPQVLTLDVEMPRMDGIDFLEKLMRLRPMPVVMISSLTAKGSEITLRALELGAVDFITKPQLGIREGMLAYSELIAEKIRTAAQAKLSVPIITPVSSAPLSFKPLLSSEKLIAVGASTGGTEAIKNLLQPLPVTSPALLITQHMPPGFTRSFAERLNKLSQITVKEAENGERILPGHAYIAPGDRHMELCRNGADYQVLITDAPAVNRHRPSVDVLFRSVAKFAGKNAVGVLLTGMGSDGAAGLLEMKQAGAYTLAQDEASCVVFGMPRAAIQMGAVDEVMDILKMSKRMLAKISSGQAVRI
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_OENOB
Sequence: MTADYGHVTVFLRQAVENLAVKTNGIYVDATLGGGGHTDLLLKKALHGHVYSFDQDENAIDFNKKRFSKEISEGRLSLIHSNFQNLIKELNLLKVFAIDGIVFDLGVSSPQFDDEKRGFSYRSDARLDMRMDQSQSLDAYQIVNTWEYKDLASIINRYGEEKFASSIARKIIKRREVQPIITTEELVETIKEALPDKILHKKGHPAKKTFQAIRIAVNDELNVLQEALKQASQLLNSGGRISVITFQSLEDRIVKHFFNQLATKNQLPSKLPVPDKFIQEEFKLLTKHPLIPSVEEIEENHRAHSAKLRVLEKN
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPH_PSEF5
Sequence: MSAFEQLFQGRLPRLVMFDLDGTLVDSVPDLAAAVDQMLLKLGRKPAGVEAVREWVGNGAPMLVRRALANSLEAQGVDDVEAEYALELFNTAYEDSHELTVVYPGARETLKWLHKQGVEMALITNKPERFVAPLLDQMKIGRYFRWIIGGDTLPQKKPDPAALFFVMKMASVPASQSLFVGDSRSDVLAAKAAGVKCVALSYGYNHGRPIAEESPALVIDNLRALIPGCLEPAAEITLPDAVPSHSGNSIVVVTRKLWMKVIKALARWRWRA
What is the function of this protein?
Specifically catalyzes the dephosphorylation of 2-phosphoglycolate.  Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.
What are the official names of this protein?
Phosphoglycolate phosphatase, PGP, PGPase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
Protein: RNK_ECOL6
Sequence: MSRPTIIINDLDAERIDILLEQPAYAGLPIADALNAELDRAQMCSPEEMPHDVVTMNSRVKFRNLSDGEVRVRTLVYPAKMTDSNTQLSVMAPVGAALLGLRVGDSIHWELPGGVATHLEVLELEYQPEAAGDYLL
What is the function of this protein?
May act as an anti-Gre factor.
What are the official names of this protein?
Regulator of nucleoside diphosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the Rnk family.
Protein: LPXD_COXB2
Sequence: MTRGLTYSLTELATAIGATVQGDGDCKIHNVAAIAQAQPGEISFVTDRKYRKYLTQTKASAILLDEKLASRCPINALVMSNPKLGFAKLLTLLRPQSLPTGGIHPTAVVGANCQIDPSAHIGAHVVIEEDVVIGPRTLIGAGASIGRGSQIGSDCCLHSRVTLYSQTRIGDRSIIHSGAVIGADGFGLIQDEKGEWVKIPQVGRVIIGDDVEIGANATIDRGALDDTVIGNGVKIDDLVMIAHNVRIGDHTVIAGCAGVAGSTTVGRHCMIGASAGLNGHIEICDNVIITGMGMIQKSITKPGIYSSGTGMQTNREWRKSVIRFWQLDELAKRLKRLEKLIR
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: DPIA_ECO57
Sequence: MTAPLTLLIVEDETPLAEMHAEYIRHIPGFSQILLAGNLAQARMMIERFKPGLILLDNYLPDGRGINLLHELVQAHYPGDVVFTTAASDMETVSEAVRCGVFDYLIKPIAYERLGQTLTRFRQRKHMLESIDSASQKQIDEMFNAYARGEPKDELPTGIDPLTLNAVRKLFKEPGVQHTAETVAQALTISRTTARRYLEYCASRHLIIAEIVHGKVGRPQRIYHSG
What is the function of this protein?
Member of the two-component regulatory system DpiA/DpiB, which is essential for expression of citrate-specific fermentation genes and genes involved in plasmid inheritance.  Could be involved in response to both the presence of citrate and external redox conditions (By similarity).
What are the official names of this protein?
Transcriptional regulatory protein DpiA, Destabilizer of plasmid inheritance.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAB20_HUMAN
Sequence: MRKPDSKIVLLGDMNVGKTSLLQRYMERRFPDTVSTVGGAFYLKQWRSYNISIWDTAGREQFHGLGSMYCRGAAAIILTYDVNHRQSLVELEDRFLGLTDTASKDCLFAIVGNKVDLTEEGALAGQEKEECSPNMDAGDRVSPRAPKQVQLEDAVALYKKILKYKMLDEQDVPAAEQMCFETSAKTGYNVDLLFETLFDLVVPMILQQRAERPSHTVDISSHKPPKRTRSGCCA
What is the function of this protein?
Plays a role in apical endocytosis/recycling.  Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S. aureus and M. tuberculosis.  Plays a role in the fusion of phagosomes with lysosomes.
What are the official names of this protein?
Ras-related protein Rab-20.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Golgi apparatus. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Note=Highly enriched on apical endocytic structures in polarized epithelial cells of kidney proximal tubules (By similarity). Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211).
Protein: LCN5_RAT
Sequence: MENIMPFALLGLCVGLAAGTEGAVVKDFDISKFLGFWYEIAFASKMGTPGLAHKEEKMGAMVVELKENLLALTTTYYSEDHCVLEKVTATEGDGPAKFQVTRLSGKKEVVVEATDYLTYAIIDITSLVAGAVHRTMKLYSRSLDDNGEALYNFRKITSDHGFSETDLYILKHDLTCVKVLQSAAESRP
What is the function of this protein?
Associates with spermatozoa in the epididymal fluid but does not bind tightly to them.  Binds both all-trans and 9-cis retinoic acid.  May act as a retinoid carrier protein which is required for epididymal function and/or sperm maturation.
What are the official names of this protein?
Epididymal-specific lipocalin-5, Androgen-dependent epididymal 18.5 kDa protein, Epididymal retinoic acid-binding protein, E-RABP, Epididymal secretory protein I, ESP-I.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted. Note=Synthesized in the proximal part of the epididymis and secreted into the epididymal fluid.
Protein: TIM54_ASHGO
Sequence: MMGEFKHPPQEKQKMSSTKKAGYSNPAFAAMGIPALRLPGPKWCAFWLVVGAGIAGVVYDKREQRRICKHYSSLVKDQGAAHMDTWLKPRRLTVFVAPPPGDYLETSMKVWRRYVKQVLFEAGLDYEVFTEERQGVIRHEVAERVRQLRRDIAAAEAAEQRALDEKRWLNRMRSWWRREKLSEEELERIRAQKFRDEFTYKQLLGVFYKNAPLREQKVWDADALVEDPVLAGGVICIGRGAYKEYIAGIHEGTLGPLDPPTLTPEAPTELSAAAEDLTQAPEQPEPSAAAEALKQAPEQAEHSPAEPDSAATDAPDEKSNNAPAPPPAPYVSPDEYSSLSLSQELVGDVRHPSSHIPALFHQPLLVIPVPNLSGFLQTPRKIYRFYTRRYYAEECCKAAAAMVLQTIRPFQPDDLNLGISEEEDWPRRWVEQGRERKSEWVQDLKADPRVIAELHVVDPALMADLAATMNLN
What is the function of this protein?
Essential component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane.  The TIM22 complex forms a twin-pore translocase that uses the membrane potential as external driving force (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit TIM54.
What is the protein family that this protein belongs to?
Belongs to the TIM54 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: SCPA_STAAN
Sequence: MYEVKLDAFNGPLDLLLHLIQKFEIDIYDIPMQALTEQYMQYVHAMKQLEINIASEYLVLASELLMIKSKMLLPQSTSDMDVDDDPREDLVGRLIEYQNYKEYTAILNDMKEERDFYFTKRPTDLSHLETDESWDPNHTIDLTELIVAYQRVKNRVELNTPKSVEIRKETFTIQQATEQVTSRLKDKDHFNFFSLFTFSEPIEQVVTHFLAILEMSKAGIINIEQQRNFEDINIIRGVNYHFG
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein A.
What is the protein family that this protein belongs to?
Belongs to the ScpA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.