PharMolix/UniProtQA huggingface dataset:
Protein: RL34_DANRE
Sequence: MVQRLTYRRRLSYNTASNKTRLSRTPGNRIVYLYTKKTGKSPKSACGICPGRLRGIRAVRPQVLMRLSKTKKHVSRAYGGSMCAKCVRDRIKRAFLIEEQKIVVKVLKAQAQTQKSK
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL34 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Endoplasmic reticulum. Note=Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).
Protein: SYV_LEGPH
Sequence: MDKTYSPEAIEKALYKKWESHHYFQPRGEGKRFCIMLPPPNVTGSLHMGHGFQHTIMDALTRYHRMLGDKTLWQPGTDHAGISTQLVVERQLEAQGVSRKDLTREQFLDKVWQWKEESGNTITQQMRRLGASVDWSRERFTMDEGLSAAVQKVFVQLYEEGLIYRGTRLVNWDPKLGTAVSDLEVLSEEEDGFLWHIRYPVVDSEEFLIVATTRPETLLGDCAVAIHPDDSRFRHLIGKQVHLPLCDRTIPVIADDYVDKEFGSGCVKITPAHDFNDHEVGKRHQLPQINILTKKGTINKNAPLKYQGMDRFVAREQIIKDLEKEGLLAKTEPHKLKVPRGEKSNVIIEPLLTDQWYVKTKPLAEPAIAAVKKGDIRFIPETWDKTYFQWMDNIEDWCISRQLWWGHRIPAWYDNHGNIYVGYSENDVRFKHKIDQSTPLKQDEDVLDTWFSSALWPFSTLGWPERTPELEQFYPTSVLVTGFDIIFFWVARMIMMGLKFTGKIPFKEVFITGLIRDSEGHKMSKSKGNVLDPLDIVDGIDLDSLIAKRTSNLMLNSVRDRITKATRKEFPEGISAYGTDALRFTYCSLASTGRNVRFDLGRVEGYRNFCNKLWNAARYVLLNTDEEQIDFGDGAFQYSPADQWILSRLQNTVSKVHHYFETYRFDLLANTLYEFVWHEYCDWYLELSKPILQDDQALSAMKRGTRRTLIHVLDQILKLLHPLMPFITEEIWQKTTKFTSENGISIMLSTYPKVNEEFINPAIEEELDWLKSAIQSLRTIRSEMSISPAKLIPLYIRNITPELKERIAKYEKILKTLSKIDKINYLAPDEKVPVSATAVLGEIELLIPMADLIDKEAELSRLNKELAKLNKDIELAQGKLNNPKFTDKAPEEIIAKEKDKLAQAQVAKDKLLQHKNRIESL
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPP21_HUMAN
Sequence: MAGPVKDREAFQRLNFLYQAAHCVLAQDPENQALARFYCYTERTIAKRLVLRRDPSVKRTLCRGCSSLLVPGLTCTQRQRRCRGQRWTVQTCLTCQRSQRFLNDPGHLLWGDRPEAQLGSQADSKPLQPLPNTAHSISDRLPEEKMQTQGSSNQ
What is the function of this protein?
Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein subunit p21, RNaseP protein p21, Ribonuclease P/MRP 21 kDa subunit, Ribonucleoprotein V.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RNPH_AGRFC
Sequence: MRPSGRKTDQMRKVSFERNFSKHAEGSCLVKFGDTHVLVTASLEEKTPPWLRNSGKGWVTAEYGMLPRSTNERMKREAASGKQGGRTQEIQRLIGRSLRAVVDLQALGERQISIDCDVIQADGGTRTASITGAWIALHDCLKWMETRNMIKVEKVLKDHIAAISCGIFAKQPVIDLDYLEDSSAETDANFVITGSGGIVEVQGTAEGAPFSEEEFLTLLGLAKAGCSELVALQKQAIA
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: ATPL_PSEF5
Sequence: METVVGLTAIAVALLIGLGALGTAIGFGLLGGKFLEGAARQPEMVPMLQVKMFIVAGLLDAVTMIGVGIALFFTFANPFVGQLAG
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CLPB_RICTY
Sequence: MNIDKFTAHAKSVIANHQSLAIKNDHQQILPLHLLSSLLSEETGIIQALINNIGGNIHLLKDQVQLELNKIPKIQVDGGGQIYYSAEDLKVLEKSRSIAKDSGDSFVTIERIFEALTYDNTIAGKILTNNGINSKKLAAAILHLRKGKKADTESAENSYDALKRYGRDVTELAKNGKLDPIIGRDEEIRRAVQVLSRRMKNNPVLIGAPGVGKTAIIEGLAQRIFNKDVPETLINCRIIELDIGALIAGAQYRGEFEKRLKSVLSEIKESSGEIILFIDELHLLVGTGKVEGAMDASNLLKPMLARGELHCIGATTLDEYRKYIEKDAALARRFQPVYVGEPSVEDTISILRGIKEKYELHHAVRISDSAIVAAATLSNRYITDRYLPDKAIDLIDEACSRMKIELSSKPEELDELDRRIIQIKIELAALKKENDEHSKKKITSLTEELKQLDSKSYDMNTKWQAAKSKLQQAQKLKEELEQARIDLDRAERDANLAKASELKYGIIPEIMNKLQAAENMDNKGLLKEIVSESDIASIISRITGIPIDTMLSSERERLLVIEQKLSESVIGQDEAIKGISDAVRRSRSGIQDINRPLGSFLFLGPTGVGKTELTKALAGFLFDDRNALLRIDMSEYMEKHSISRLIGAPPGYIGYDQGGVLTESVRRRPYQVILFDEVEKAHLDIFNIMLQILDEGRLTNSQGITVDFKNTIIVLTSNLGAEILVNQQEDEDTYKVKDEVMQYVRAVFKPEFLNRLDEIILFHRLNRNNIYDIVKIQLGSLKKILLQQNIILEFNESALNYLAEKGYDPSFGARPLKRLIQREIQNNLAKMILAGKISSGNTVKIAREKEELRIEIID
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYCP2_ARATH
Sequence: MQKLGFPAMKSFDQLRSLPGSAKTYFFSTRPPQDSVSSGSFSNLKLTAEKLVKDQAAMRTDLELANCKLKKSMEHVYALEEKLQSAFNENAKLRVRQKEDEKLWRGLESKFSSTKTLCDQLTETLQHLASQVQDAEKDKGFFETKFNTSSEAINSLNQQMRDMSLRLDAAKEEITSRDKELEELKLEKQHKEMFYQTERCGTASLIEKKDAVITELETTAAERKLKIEKLNSQLEKLHLELTTKEDEVIHLVSIQEKLEKEKTNVQLSSDELFEKLVRSEQEVKKLDELVHYLIAELTELDKKNLTFKEKFDKLSGLYDTHFMLLRKDRDLASDRAQRSFDQLQGELFRVAAEKEALESSGNELSEKIVELQNDKESLISQLSGVRCSASQTIDKLEFEAKGLVLKNAETESVISKLKEEIDTLLESVRTSEDKKKELSIKLSSLEIESKDKYEKLQADAQRQVGELETLQKESESHQLQADLLAKEVNQLQTIIEEKGHLILQCNENEKNINQQIIKDKELLATAETKLAEAKKQYDLMLESKQLELSRHLKELSQRNDQAINEIRRKYDVEKHEIINSEKDKVEKIIKELSTKYDKGLSDCKEESKRQLLTIQEEHSSRILNIREEHESKELNLKAKYDQELRQNQIQAENELKERITALKSEHDAQLKAFKCQYEDDCKKLQEELDLQRKKEERQRALVQLQWKVMSDNPPEEQEVNSNKDYSHSSVKVKESRLGGNKRSEHITESPFVKAKVTSVSNILKEATNPKHHSKVTHREYEVETNNGRIPKRRKTRQTTMFQEPQRRSTRLTPKLMTPTIIAKETAMADHPHSANIGDLFSEGSLNPYADDPYAFD
What is the function of this protein?
Required for chromosome synapsis and normal fidelity of crossing over.
What are the official names of this protein?
Synaptonemal complex protein 2, Synaptonemal complex central region protein ZYP1b.
What are the subcellular locations of this protein?
Nucleus.
Protein: DNMT1_ARATH
Sequence: MVENGAKAAKRKKRPLPEIQEVEDVPRTRRPRRAAACTSFKEKSIRVCEKSATIEVKKQQIVEEEFLALRLTALETDVEDRPTRRLNDFVLFDSDGVPQPLEMLEIHDIFVSGAILPSDVCTDKEKEKGVRCTSFGRVEHWSISGYEDGSPVIWISTELADYDCRKPAASYRKVYDYFYEKARASVAVYKKLSKSSGGDPDIGLEELLAAVVRSMSSGSKYFSSGAAIIDFVISQGDFIYNQLAGLDETAKKHESSYVEIPVLVALREKSSKIDKPLQRERNPSNGVRIKEVSQVAESEALTSDQLVDGTDDDRRYAILLQDEENRKSMQQPRKNSSSGSASNMFYIKINEDEIANDYPLPSYYKTSEEETDELILYDASYEVQSEHLPHRMLHNWALYNSDLRFISLELLPMKQCDDIDVNIFGSGVVTDDNGSWISLNDPDSGSQSHDPDGMCIFLSQIKEWMIEFGSDDIISISIRTDVAWYRLGKPSKLYAPWWKPVLKTARVGISILTFLRVESRVARLSFADVTKRLSGLQANDKAYISSDPLAVERYLVVHGQIILQLFAVYPDDNVKRCPFVVGLASKLEDRHHTKWIIKKKKISLKELNLNPRAGMAPVASKRKAMQATTTRLVNRIWGEFYSNYSPEDPLQATAAENGEDEVEEEGGNGEEEVEEEGENGLTEDTVPEPVEVQKPHTPKKIRGSSGKREIKWDGESLGKTSAGEPLYQQALVGGEMVAVGGAVTLEVDDPDEMPAIYFVEYMFESTDHCKMLHGRFLQRGSMTVLGNAANERELFLTNECMTTQLKDIKGVASFEIRSRPWGHQYRKKNITADKLDWARALERKVKDLPTEYYCKSLYSPERGGFFSLPLSDIGRSSGFCTSCKIREDEEKRSTIKLNVSKTGFFINGIEYSVEDFVYVNPDSIGGLKEGSKTSFKSGRNIGLRAYVVCQLLEIVPKESRKADLGSFDVKVRRFYRPEDVSAEKAYASDIQELYFSQDTVVLPPGALEGKCEVRKKSDMPLSREYPISDHIFFCDLFFDTSKGSLKQLPANMKPKFSTIKDDTLLRKKKGKGVESEIESEIVKPVEPPKEIRLATLDIFAGCGGLSHGLKKAGVSDAKWAIEYEEPAGQAFKQNHPESTVFVDNCNVILRAIMEKGGDQDDCVSTTEANELAAKLTEEQKSTLPLPGQVDFINGGPPCQGFSGMNRFNQSSWSKVQCEMILAFLSFADYFRPRYFLLENVRTFVSFNKGQTFQLTLASLLEMGYQVRFGILEAGAYGVSQSRKRAFIWAAAPEEVLPEWPEPMHVFGVPKLKISLSQGLHYAAVRSTALGAPFRPITVRDTIGDLPSVENGDSRTNKEYKEVAVSWFQKEIRGNTIALTDHICKAMNELNLIRCKLIPTRPGADWHDLPKRKVTLSDGRVEEMIPFCLPNTAERHNGWKGLYGRLDWQGNFPTSVTDPQPMGKVGMCFHPEQHRILTVRECARSQGFPDSYEFAGNINHKHRQIGNAVPPPLAFALGRKLKEALHLKKSPQHQP
What is the function of this protein?
Maintains chromatin CpG methylation that plays a role in genomic imprinting, regulation of embryogenesis and seed viability.  Required for proper patterns of CG DNA methylation in dividing cells.  Required for MEA promoter methylation in seeds.
What are the official names of this protein?
DNA (cytosine-5)-methyltransferase 1, DNA methyltransferase 01, DNA methyltransferase 2, DNA methyltransferase AthI, DNA Metase AthI, M.AthI, DNA methyltransferase DDM2, Protein DECREASED DNA METHYLATION 2.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SECA_STRGG
Sequence: MSVFNKLMRAGEGKILRKLHRIADQVSSIEEDFVNLSDAELRALTDEYKERYADGESLDDLLPEAFATVREAAKRVLGQRHYDVQMMGGAALHLGYVAEMKTGEGKTLVGTLPAYLNALSGKGVHLITVNDYLAERDSELMGRVHKFLGLSVGCIVANMTPAQRREQYGCDITYGTNNEFGFDYLRDNMAWSKDELVQRGHNFAVVDEVDSILVDEARTPLIISGPADQATKWYGDFAKLVTRLTKGEAGNQLKGIEETGDYEVDEKKRTVAIHEAGVAKVEDWLGIDNLYESVNTPLVGYLNNAIKAKELFKKDKDYVVIDGEVMIVDEHTGRILAGRRYNEGMHQAIEAKEGVDIKDENQTLATITLQNFFRLYDKLSGMTGTAMTEAAEFHQIYKLGVVPIPTNRPMVRADQSDLIYRTEVAKFAAVVDDIAEKHEKGQPILVGTTSVEKSEYLSQQLSKRGVQHEVLNAKQHDREATIVAQAGRKGAVTVATNMAGRGTDIKLGGNPDDLAEAELRQRGLDPVENVEEWAAALPAALETAEQAVKAEFEEVKDLGGLYVLGTERHESRRIDNQLRGRSGRQGDPGESRFYLSLGDDLMRLFKAQMVERVMSMANVPDDVPIENKMVTRAIASAQSQVEQQNFETRKNVLKYDEVLNRQREVIYGERRRVLEGEDLQEQIRHFMDDTIDDYIRQETAEGFAEEWDLDRLWGAFKQLYPVKVTVDELEEAAGDLAGVTAEFIAESVKNDIHEQYEERENTLGSDIMRELERRVVLSVLDRKWREHLYEMDYLQEGIGLRAMAQKDPLVEYQREGFDMFNAMMEGIKEESVGYLFNLEVQVEQQVEEVPVQDGAERPSLEKEGATAAPQIRAKGLEAPQRPDRLHFSAPTVDGEGGVVEGDFANDEATGDTRSGSADGMTRAERRKAQKGGGGRRRKK
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: NNRE_OENOB
Sequence: MTTIYISSKQAHNFDDYTINKIGVPSSVLMERAALAVCQRLLESRNFNLKKVLVVAGIGNNGGDGIAVARMLYLKQVPVKIYLLGDREKISKDSRIQLKIAENYGVPFVSNIDDLSSYTTIVDAVFGVGLSRDVTGEIAGIVDFINNSPASVMAVDMPTGLNADNGNIMGTAVKAAETVTMSYNKLGLISETGRKFAGVVTVADIGIYEP
What is the function of this protein?
Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
What are the official names of this protein?
NAD(P)H-hydrate epimerase, NAD(P)HX epimerase.
What is the protein family that this protein belongs to?
Belongs to the NnrE/AIBP family.
Protein: FPRB_MYCLE
Sequence: MPYIITQSCCNDGSCVFACPVNCIHPTPDEPGFATSEMLYIDPVACVDCGACVSACPVGAIASDTRLAPKQLPFIEINASYYPARPIDLKLPPTSKLAPVIPAAQVHVRRRPLTVAIVGSGPAAMYAADELLTQPGVWVNVFEKLPTPYGLVRAGLAPDHQNTKKVTELFDRVAEHRRFRFFLNVEIGRHLSHDELLAHHHAVLYAVGAPDDRRLNIDGMGIPGTGTATELVAWINAHPDFAYLPVDLSHERVVVIGNGNVALDVARLLTADPDNLARTDISEFALHVLGGSAVREVVVAARRGPAHSAFTLPELIGLKATSEVVLDAGDRKLVEGDFATVSDSLTRKKLEVLSSLVDSSKPTSRRRIRLAYQLTPKRVLGNQRATGVEFSVTGTEESRRFDAGLVLTSVGYRGKRIRDLPFDEEAAVIPNDGGRVVDPSRGRPMPGAYVAGWIKRGPTGFIGTNKLCSVQTVQAVVADFNAGWLTDPVAEPAELAKLVHARQPDTVDSVGWRAIDAAEIAQGSTEGRPRRKFTDVADMLAVAAGAPPLRLRALS
What are the official names of this protein?
Probable ferredoxin/ferredoxin--NADP reductase, FNR.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the ferredoxin--NADP reductase family.
Protein: COX41_PANTR
Sequence: SVVKSEDFSLPAYMDRRDHPLPEVAHVKHLSASQKALKEKEKASWSSLSMDEKVELYRIKFKESFAEMNRGSNEWKTVVGGAMFFIGFTALVIMWQKHYVYGPLPQSFDKEWVAKQTKRMLDMKVNPIQGLASKWDYEKNEWKK
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial, Cytochrome c oxidase polypeptide IV, Cytochrome c oxidase subunit IV isoform 1, COX IV-1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase IV family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: YL283_YEAST
Sequence: MMRLIRTLPLRCFKTRIRRQGSLLCLRCFSSYSKPLLQKSMSLKNIQLSDLSSSPLSKNKEKQEKPEKENEGKHSIGLLDRFSEDFITQGNGLKPTTSQNQLDTIKFYQMLRERGNFSDEQCKIIIALLLQLLNDQFYSCYNDLFLRDMELNKQSHLFSSLETELKFAIQNSRDTQLNEHHLQLLKLKRELNSIHDELNEIIIDLLQKDAKLEFNNQKLENTLLYRQLNLKLNDCSNKIQTKILGDIRSHIENLRWQTTRSGLLVILVLVCSIMIGVSASKKERPGLQEPEEPEILAPKEDIDTTFPQDQHDID
What are the official names of this protein?
Uncharacterized protein YLR283W, mitochondrial.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: SCMU_MYCTU
Sequence: MLTRPREIYLATAVSIGILLSLIAPLGPPLARADGTSQLAELVDAAAERLEVADPVAAFKWRAQLPIEDSGRVEQQLAKLGEDARSQHIDPDYVTRVFDDQIRATEAIEYSRFSDWKLNPASAPPEPPDLSASRSAIDSLNNRMLSQIWSHWSLLSAPSCAAQLDRAKRDIVRSRHLDSLYQRALTTATQSYCQALPPA
What is the function of this protein?
Catalyzes the Claisen rearrangement of chorismate to prephenate.  May play some role in the pathogenicity.
What are the official names of this protein?
Secreted chorismate mutase, CM, *MtCM.
What are the subcellular locations of this protein?
Secreted.
Protein: EFTS_DESVV
Sequence: MAITASMVKELREKTSAGMMDCKKALEECGGEMDKAVDWLRQKGLSKAAKKAGRATSEGLVGCFVSADGKTAGLAELKCETDFVSRNEKFVELAGKLAEQVATKGALDESAQTAINDIIATLGENMGSGRTAQMNVAGEGFIGSYLHSNGKIAVLVEMTCEKAATAAEATFLECAKNVAMQIAASNPAAVSADKVDPALIAREREVYRQKALEEGKPENIVEKIAEGAVKKFFKEACLLEQPYIRDDKTTVAELLKQTSKAVGDNLGVARFVRFQLGEDAAAEEAAE
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE2_PSECP
Sequence: MIPGEYVLRPEPVTANAGRDAIELSVTNTGDRPVQVGSHFHFAEANAALDFDRAAARGRRLDIPAGTAARFEPGDSRSVRLIELAGSREVFGLSNAVNGKLDGGPHPGVPATERGAK
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPARD_HUMAN
Sequence: MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQMGCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKKNRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSKHIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKEISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKDGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGDRPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRIKKTETETSLHPLLQEIYKDMY
What is the function of this protein?
Ligand-activated transcription factor key mediator of energy metabolism in adipose tissues (PubMed:35675826).  Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids.  Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid.  Once activated by a ligand, the receptor binds to promoter elements of target genes.  Regulates the peroxisomal beta-oxidation pathway of fatty acids.  Functions as transcription activator for the acyl-CoA oxidase gene.  Decreases expression of NPC1L1 once activated by a ligand.
What are the official names of this protein?
Peroxisome proliferator-activated receptor delta, PPAR-delta, NUCI, Nuclear hormone receptor 1, NUC1, Nuclear receptor subfamily 1 group C member 2, Peroxisome proliferator-activated receptor beta, PPAR-beta.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLO2_SYNS9
Sequence: MHSTLHALPVLQDNVIWIWARGKNAVVVDPAVAEPVNQWLNAHGMCLRAILQTHHHADHIGGTPDLLREWPQAEVVAATADRLRIPLQTRGVADGDVINLLGRRLEVIDVAAHTSAHIAFIIRNDDDQDPSFGPLAFCGDTLFAGGCGRLFEGSAQDMYRALQRFAALPDETLVCCAHEYTEANLRWATEQRPNDVQITTRHQTVKALRSRGDLSLPSSIGAEKRTNLFMQAETAEQLAELRSHKDHWRSS
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: CD006_HUMAN
Sequence: MDTQKQIHKTHNSKNQFFTIFFFLSVEFGKEGTRKNFYLLLSIGHYGRKSRRADLGTADTADKTEPECFAASWTFDPNPSVTVSGAHSTAVHQ
What are the official names of this protein?
Uncharacterized protein encoded by LINC01587, Protein AC1.
Protein: NUOH_ECOHS
Sequence: MSWISPELIEILLTILKAVVILLVVVTCGAFMSFGERRLLGLFQNRYGPNRVGWGGSLQLVADMIKMFFKEDWIPKFSDRVIFTLAPMIAFTSLLLAFAIVPVSPGWVVADLNIGILFFLMMAGLAVYAVLFAGWSSNNKYSLLGAMRASAQTLSYEVFLGLSLMGVVAQAGSFNMTDIVNSQAHVWNVIPQFFGFITFAIAGVAVCHRHPFDQPEAEQELADGYHIEYSGMKFGLFFVGEYIGIVTISALMVTLFFGGWQGPLLPPFIWFALKTAFFMMMFILIRASLPRPRYDQVMSFGWKICLPLTLINLLVTAAVILWQAQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CAS6A_METJA
Sequence: MRESMRIELELQTDNFTVIPYNHQYYLASAIYNKIHSANPAYAKRLHNYQKFKFFTFSLLQIRKRVIRKEGIETIDGKAYLYISSPNNEFIENFVAGLLEDGKLRVGNVEFFVRKAKILPIPKKFNILKTISPIYLKTMIETEDGLKTYDLLPNNSKFYENLKNNLKKKYEAFYNEKCDMNFEFEVLKFRPKRMRIKNDIYCRCSEMVFKVWGDYDLIKFGYECGFGEKNSMGFGMVVNVEDKNQKNKKLKTKI
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  This protein processes pre-crRNA into individual crRNA units.
What are the official names of this protein?
CRISPR-associated endoribonuclease Cas6 1.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
Protein: HO1_NOSS1
Sequence: MSSNLANKLRVGTKKAHTMAENVGFVKCFLKGVVEKSSYRKLVANFYYVYSAMEEEMEKHSQHPIVSKINFSQLNRKQTLEQDLSYYYGANWREQIQLSPAGEAYVQRIREISATEPELLIAHSYTRYLGDLSGGQILKNIAVTAMNLNDGQGTAFYEFADISDEKAFKAKYRQTLDELAIDEATGDRIVDEANAAFGMNMKMFQELEGNLIKAIGMMLFNTLTRKRTRGATELATAE
What is the function of this protein?
Catalyzes the opening of the heme ring with the release of iron.  Key enzyme in the synthesis of the chromophoric part of the photosynthetic antennae (By similarity).  Upon overexpression in E. coli with PCB:ferredoxin oxidoreductase, CpeS and either CpcB or PecB permits synthesis of phycocyanin-coupled CpcB or PecB.
What are the official names of this protein?
Heme oxygenase 1.
What is the protein family that this protein belongs to?
Belongs to the heme oxygenase family.
Protein: NEU1_CATCO
Sequence: MSGSMFSVFSLLYLLSVCSACYISNCPIGGKRAIQDSPSRQCMSCGPGDRGRCFGPSICCGEGLGCLLGSPETQRCLEEDFLPSPCEAGGKVCGYEGRCAAPGVCCDSEGCSVDQSCVDGDGDATAVSQPASSQDLLLKLLHLSNPAHPYRLHQ
What is the function of this protein?
Isotocin causes contraction of smooth muscles.
What are the official names of this protein?
Isotocin-neurophysin IT 1.
What is the protein family that this protein belongs to?
Belongs to the vasopressin/oxytocin family.
Protein: RIBBA_CHLPM
Sequence: MENKRIDTIESALEDIGQGKLVIVIDDEERENEGDFIAAADKVTTEMINFITKEARGLLCVAVTMDRAKELQLEPMVQRNTSQHETNFTVSVDAIAEGVTTGISVYDRAMTIKMLGDETSHADSFSRPGHIFPLRAMDGGVLRRVGHTEAAVDLARLAGCSPVGLLCEILHEDGSMARLADLMTIKEKFGLKLITIKDLVAFQMRRSKLVQRAVESNIPTAYGEFRLMAYESFTDQQNHMAFVKGDVSTDEPVLVRVHSQCATGDTFASLRCDCGNQLASALRMIEKEGRGVLVYLMQEGRGIGLINKLKAYNLQDDGFDTVEANEELGFKADLRDYGIGAQILQDLGVRKMRLMTNNPKKVVGLEGYGLEIVERVPLEIEPNAVNKTYLETKRDKMGHMISCSCGSGNH
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
Riboflavin biosynthesis protein RibBA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the GTP cyclohydrolase II family.