PharMolix/UniProtQA huggingface dataset:
Protein: NUON_CAMFF
Sequence: MIALLPFILSLAATFINIFLCVTNISKRYSINLNILFWVIIFISFFIVRSNFSNDFLMDFATPFISLDEFSFCFGVVLSALMIIFLISSFYSDDEKFYKQEMFALASLAGFGLLAMSLSVELILTLIFLEVASISIYAMIAMNSIEYKSVEAAFKYFLLSSFMSAFYLLGAAFVFGVAGSTKYSFIATGLNSDFLSIIGMILVLSMMFFKIAIFGFYRWSIDVYYGSNLNIAGFLASAFKLASFAILIKLCFLYPGNNIEILQGIFAILAILSMFAGNLLSLKETNVKKILIAAGIVHSGYIFINLSSVGASVSIYPAIFYLSTYTIVVGFLFAILNGLFGDREIKISDLNGLYKVRPTEAFAFTVICLSFIGFPYSVGFLGKLFIFSSAVESGKTYLAIFGIINTIFSVYYYLKIIISIYFSENKTALSCADSKKFGLKLLALSSILFIILEGSGIFSIISFLNLFIR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NEP_I97A0
Sequence: MNSNTVSSFQDILKRMSKMQLGSSSEDLNGIITQFESLKLYRDSLGEAVMRMGDLYSLQNRNGKWREQLSQKFEEIRWLIEEVRHRLRITENSFEQITFMQALQLLLEVEQEIRTFSFQLI
What is the function of this protein?
Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs).  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell.  Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain.  This domain is believed to allow recognition of RNPs bound to the protein M1.  Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized.  Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane.  May down-regulate viral RNA synthesis when overproduced.
What are the official names of this protein?
Nuclear export protein, NEP, Non-structural protein 2, NS2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses NEP family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: TRUD_SHIDS
Sequence: MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHILVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDLSAFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLIDICVKGVPNYFGAQRFGIGGSNLQGALRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQVVDGDALQLAGRGSWFVATTEELAELQRRVNDKELMITAALPGSGEWGTQREALAFEQAAVAAETELQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVVRELINTTGDYAHIAE
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: GH109_ELIME
Sequence: MGALIPSSTLFNIFDFNPKKVRIAFIAVGLRGQTHVENMARRDDVEIVAFADPDPYMVGRAQEILKKNGKKPAKVFGNGNDDYKNMLKDKNIDAVFVSSPWEWHHEHGVAAMKAGKIVGMEVSGAITLEECWDYVKVSEQTGVPLMALENVCYRRDVMAILNMVRKGMFGELVHGTGGYQHDLRPVLFNSGINGKNGDGVEFGEKAFSEAKWRTNHYKNRNGELYPTHGVGPLHTMMDINRGNRLLRLSSFASKARGLHKYIVDKGGESHPNAKVEWKQGDIVTTQIQCHNGETIVLTHDTSLQRPYNLGFKVQGTEGLWEDFGWGEAAQGFIYFEKIMNHSHRWDSSEKWIKEYDHPMWKKHEQKAVGAGHGGMDYFLDNTFVECIKRNEAFPLDVYDLATWYSITPLSEKSIAENGAVQEIPDFTNGKWKNAKNTFAINDDY
What is the function of this protein?
Glycosidase that has specific alpha-N-acetylgalactosaminidase activity.
What are the official names of this protein?
Alpha-N-acetylgalactosaminidase, Glycosyl hydrolase family 109 protein.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.
Protein: EFTS_CORU7
Sequence: MANYTAADVKKLREMTGSGMMDCKKALVEAEGDFDKAIEILRIQGAKDVGKRAERSASEGLIAVSGNTMIEVNAETDFVAKNQEFIDFANKVAQAADAANANSREELEAVEVDGVKAVDALQELSAKIGEKLELKRAVTLEGDKVAVYLHQRSADLPPAVGVLVAYEGENEEAARAAAMQVAALKASFLSTDDIPAETVAKEREIAEATAREEGKPEKALPNIIEGRLKGYFKDVVLLEQPSVTESKKTVKQVMDEAGVKLTGFVRYELGQA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBA_ARAHI
Sequence: MTAILERRESESLWGRFCNWITSTENRLYIGWFGVLMIPTLLTATSVFIIAFIAAPPVDIDGIREPVSGSLLYGNNIISGAIIPTSAAIGLHFYPIWEAASVDEWLYNGGPYELIVLHFLLGVACYMGREWELSFRLGMRPWIAVAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANEGYRFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGIWFTALGISTMAFNLNGFNFNQSVVDSQGRVINTWADIINRANLGMEVMHERNAHNFPLDLAAVEAPSTNG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PSAH_PEA
Sequence: KYGDKSVYFDLEDIGNTTGQWDLYGSDAPSPYSXLQ
What is the function of this protein?
Possible role could be the docking of the LHC I antenna complex to the core complex.
What are the official names of this protein?
Photosystem I reaction center subunit VI, Light-harvesting complex I 11 kDa protein, PSI-H.
What is the protein family that this protein belongs to?
Belongs to the psaH family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single- pass membrane protein.
Protein: IL33_RAT
Sequence: MRPRMKYSNSKISPAKCDSTSGRALVPPCKITRSQQKTKDICHVYCMRLRSGLTIRKETCYFGKEPAKRYSLKSGSKHEGRLSTCLPDSRKRSLLGSIQAFAASVDTLSIQGTSLLTESCALSTYNDQSVSFVLENGCYVINVEDCGKNQEKDKVLLRYYESSFPAQSGDGVDGKKLMVNMSPIKDTDIWLNANDKDYSVELQKGDVSPPDQAFFVLHKKSSDFVSFECKNLPGTYIGVKDNQLALVEENDESCNNIMFKLSKM
What is the function of this protein?
In quiescent endothelia the uncleaved form is constitutively and abundantly expressed, and acts as a chromatin-associated nuclear factor with transcriptional repressor properties, it may sequester nuclear NF-kappaB/RELA, lowering expression of its targets.  This form is rapidely lost upon angiogenic or pro-inflammatory activation (By similarity).
What are the official names of this protein?
Interleukin-33, IL-33.
What is the protein family that this protein belongs to?
Belongs to the IL-1 family. Highly divergent.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Cytoplasm. Cytoplasmic vesicle, secretory vesicle. Secreted. Note=Associates with heterochromatin and mitotic chromosomes. The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion.
Protein: GLO2_SHEB2
Sequence: MLTITAIKAFNDNYIWVLQQQPHTQVYVVDPGDASVVIDYLEANQLTLAGILLTHHHNDHTGGVAELQAYSQDRLTVYGPDNEKIEGITHPLNATAQPRLTLDYMSGELQVLDVPGHTAGHIAYVIADALFCGDTLFSGGCGRLFEGTPAQMLNSLQQLAQLPADTRVYCAHEYTFSNLKFALAVNPNNRALQDYNERAIALRRQDKATIPSTIALERAINPFLRASDTEIVDSIKQHFSDLNHANLDELGGFTLLRQWKDNF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: BBE11_ARATH
Sequence: MEKLLIICMLLISVLVATSQSQTDPETFLRCLVREGSNPQVFISDVTYIPSNSSFTTVLRRRIPNLRFDKPTTPKPIAIITPTTWSHISPVLACARLFPVQVRIRSGGHDFEGLSYTSTAPFFLIDLLNFKSVDVNLTEGTAWVDTGATLGELYYKIAEKSNVLGFPAGLCTTLGVGGHISGGGYGTMMRKYGLSVDNVVGSRIIDSNGNTYFDRMSMGEELFWAVRGGGAASFGIVMGYKIRLVPVPEKVTVFSVGKTVGEGAVDLIMKWQNFSHSTDRNLFVKLTLTLVNGAKPGEKKVLATFIGMNLGGFDKTLNVMNRDFPELKLKKTDCTEMRWIDSVLFWAGYPVGTPTSVLLNPTVTKKLFMKRKSDYVKRPVSRTGLGLILKKLVELEKVEMNWNPYGGRMGEIPSSRTPFPHRGGNLFNIEYIIDWSEAGDNVEKKYLALANEFYRFMTPYVSSNPREAFLNYRDIDIGSSGNSTYEEGKIYGAKYFKDNFERLVDIKTKFDEINFWRNEQSIPVRK
What are the official names of this protein?
Berberine bridge enzyme-like 11, AtBBE-like 11.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: HEM3_CORA7
Sequence: MLKIGTRGSLLATTQSGHVQEWLQQKGYEAELHIVTTQGDVNMAPVERIGVGVFTQALREAVDRGECEIAVHSFKDLPTAADERFDLVVPQRQDVREALIARDGLTLKELPEGARVGTSAPRRISQLRAMRPDLDIRPLRGNIDTRMGKVTSGELDAVLLAYAGLVRAGYAERATEVFDPEVFMPAPAQGALAIEAVKGTEAAKAIALLADGPATAATRAERTVLSQLEAGCTAPVAATSHWEGEQLVVRGGVFALDGSRQLIAQAQGAASEAEELGRAVSKELFAQGAADVLAAE
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: FTHS_CLOBK
Sequence: MFKSDIEIAQESKMKNIKNIAEKIGLTEEDIDLYGKYKCKISLDVLESNKDKKDGKLILVTAINPTPAGEGKSTVTVGLGQALWKKNKKAVIALREPSLGPVFGIKGGAAGGGYSQVVPMEDINLHFTGDMHAITSANNLLAAAIDNHIHQGNILKIDQRRILFKRVMDMNDRALRNVIVALGGKINGFPREDGFMITVASEIMAILCLAEDLMDLKNKMGEILVAYSTEGKPIYCKDLEVQGAMALLMKDAIKPNLVQTLENTPAIIHGGPFANIAHGCNSILGTKMALKLGDYVITEAGFGADLGAEKFFDIKCRKANLKPNCVVIVATVRALKYNGGIPKENLKEQNMEALSKGIKNLGKHIENVNKFGVPAVVAINKFISDTEEEIEFIKKYCKELGAEVSIAEVWEKGGNGGLELADKVLDTIENKESKFNPIYEETLNIKQKIETIAQEIYGAEGVDYSKEAEKQISEIEKLDLDKKPVCMAKTQYSLSDDAKLLGRPCGFRINVKEVRISNGAGFIVVLTGNVMTMPGLPKKPAANNMDVLSDGNIVGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: RL24_SERP5
Sequence: MAAKIRRDDEIIVLTGKDKGKRGKVKNVLSAGKVIVEGINLVKKHQKPVPALNQPGGIVEKEAAIQVSNIALFNAATGKADRVGFRFEDGKKVRFFKSNSETIK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: UREG_BURP0
Sequence: MNAPRFAAPARRTKKLPPLRVGIGGPVGSGKTTLLEMLCKGMRERYDLVAITNDIYTKEDQRLLTIAGALPEARIMGVETGGCPHTAIREDASINLEAVERMLARFPDADIVFIESGGDNLAATFSPELSDLTIYVIDVAGGEKIPRKGGPGITKSDLLVINKTDLAPLVGANLEVMASDTRKMRGERPYVMCNLKALDGVADVIAFIENKGLLTV
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCFT_XENLA
Sequence: MVSPDDSPEIRDRPRPRRCLLPASVTVEPVIFLSMFALALQGPLATQYLWDRLSADIGFNGTRTVGCAMNGSKSAGPEQQEVETLTAHWSLYINLGGFLVGLFSVMLLGPWSDKVGRRPVLMLPCIGLALQAAVYLLVMYQELHVGYFLIGRFISGISGDFNMILAGCFAYIADVSDRQSRTFRVAVLEACLGIAGMVASIIGGHWRKAQGYINPFWLVFAVNLFTALYVYFCVEESVKDKKPARLFTHRHYQSFFRLFTVQGENNRRRKLFLYSLALLVVVTVHMGAKNLFVLYELSYPLCWDSDLIGYGSAAEHLTYLSSLAGLRLFQLCLADSWVAEMGFISNISGLVVISLASTTPIMFTGYGLRFFAMATTPVIRSKLSKMVEEGEQGALFSSVACVEGLSFLLATGLFNSLYPATLHFMKGFPFLLGALLLLIPAGIIGLIEVCEQKPMYSQFSEIS
What is the function of this protein?
Proton-coupled folate symporter that mediates folate absorption using an H(+) gradient as a driving force (By similarity).  Involved in the intestinal absorption of folates at the brush-border membrane of the proximal jejunum, and the transport from blood to cerebrospinal fluid across the choroid plexus (By similarity).  Functions at acidic pH via alternate outward- and inward-open conformation states (By similarity).  Protonation of residues in the outward open state primes the protein for transport (By similarity).  Binding of folate promotes breaking of salt bridge network and subsequent closure of the extracellular gate, leading to the inward-open state and release of protons and folate (By similarity).  Also able to transport antifolate drugs, such as methotrexate and pemetrexed (By similarity).  Also acts as a lower-affinity, pH-independent heme carrier protein and constitutes the main importer of heme in the intestine (PubMed:16143108).  Imports heme in the retina and retinal pigment epithelium, in neurons of the hippocampus, in hepatocytes and in the renal epithelial cells (By similarity).
What are the official names of this protein?
Proton-coupled folate transporter, Heme carrier protein 1, Solute carrier family 46 member 1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. SLC46A family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Endosome membrane; Multi- pass membrane protein. Cytoplasm. Note=Localizes to the apical membrane of intestinal cells in iron-deficient cells, while it resides in the cytoplasm in iron-replete cells (By similarity). Localizes to the basolateral membrane of choroid plexus (By similarity).
Protein: BIOD_BURO1
Sequence: MTAPLSVFVTGTDTEIGKTFVSAAMLHGFARHGLRAAALKPVAAGAYERDGVWRNEDADQLDAAANVALPPELRTPFLLKAPAAPHIVAAQEGVTLDLDTIVACHREALTRADVVVVEGVGGFRVPLNDTQDTADLAVALGLPVVLVVGVRLGCISHALLTADAIRQRGLTLAGWVANHVDPAMSFADENVATIRDWLAREHRAPLIGRIAHMTPAAPESAAAMLDIAALVESLRTARR
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
Protein: RL22_PECAS
Sequence: METIAKHCHARSSAQKVRLVADLIRGKKVSQALEVLTYTNKKAAGLVKKVLESAIANAEHNDGADIDDLKVAKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RL35_SHEON
Sequence: MPKMKTDRGVAKRFKKTANGFKRKQAHLRHILTKKSTKRKRHLRNKCLVAKVDVPAIARQLPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: AROE_STRPN
Sequence: MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEIEASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLIGYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEKTRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVLPETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIWQSLTEKYQ
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: RECX_ECO7I
Sequence: MTESTSRRPAYARLLDRAARILAVRDHSEQELRRKLAAPIMGKNGPEEIDATAEDYERVIAWCHEHGYLDDSRFVARFIASRSRKGYGPARIRQELNQKGISREATEKAMRECDIDWCALARDQATRKYGEPLPTVFSEKVKIQRFLLYRGYLMEDIQDIWRNFAD
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_LEUCK
Sequence: MRQNTILENVTSAQLRSDIPEFRAGDTVKVYAKIVEGSRERIQLFEGVVIKRKGSGIQATYTVRKISSGVGVERTFPLHSPRVEKIEVVRFGAVRRAKLYYLRALQGKAARIKERRRDV
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: Y1543_MYCBP
Sequence: MTLPLLGPMTLSGFAHSWFFLFLFVVAGLVALYILMQLARQRRMLRFANMELLESVAPKRPSRWRHVPAILLVLSLLLFTIAMAGPTHDVRIPRNRAVVMLVIDVSQSMRATDVEPSRMVAAQEAAKQFADELTPGINLGLIAYAGTATVLVSPTTNREATKNALDKLQFADRTATGEAIFTALQAIATVGAVIGGGDTPPPARIVLFSDGKETMPTNPDNPKGAYTAARTAKDQGVPISTISFGTPYGFVEIDDQRQPVPVDDETMKKVAQLSGGNSYNAATLAELRAVYSSLQQQIGYETIKGDASVGWLRLGALALALAALAALLINRRLPT
What are the official names of this protein?
UPF0353 protein BCG_1543.
What is the protein family that this protein belongs to?
Belongs to the UPF0353 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: THIG_YERPY
Sequence: MLKIADTTFTSRLFTGTGKFSSPELMLEALRASGSQLITMAMKRVDLQSGNDAILAPLRQLGVRLLPNTSGAKTAEEAIFAARLAREALNTHWVKLEIHPDVRYLLPDPIETLKAAEVLVKEGFVVLPYCGADPVLCKRLEEVGCAAVMPLGSPIGSNLGLRTRDFLQIIIEQSKVPVVVDAGIGAPSHALEALELGADAVLVNTAIAVAHSPVQMAHAFRLAVESGERARLAGLGASPFNPSQPDTLQLRATATSPLTGFLSQLEEQEHV
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KYNU_DICDI
Sequence: MDKFFEYIKNQNLSLEDEKLADKLDQLDQLSSIKEEFYFPITKDIATDLSRVKDEDLDKPVIYLTGNSLGLQPKEIEKQLVCNYLNDWRKYGVEGHHKGDHPFIHIDEEIQASLSKIVGALPSEVCPMNSLSTNIHVLLSNFYKPTQTRHKIIIEYGAFPSDLYVTESQIRHNSFNPETSLIKIKPRDGEYTLRTDDIINVLKEHGDSVAVVMLSGIQYFTGQFFDMKKITEVGHEIGAIVGWDLAHAAGNVELSLHDWNVDFACWCTYKYLNSGPGCIAGIFVHSKHTESFNLSTDSRLLGWFGNKLSNRFQKEKEFVAEDGALGFRMSNPSVADCTALRASLSVFEKAGGIKKLAEKSTIITGYLEYLLTHKLKTTDVQIITPSEANQRGSQLSLLIKGIKASQLKVNLSNSGIVCDVRDPDVIRVAPAPLYTSFNDVKYFIQKLNENM
What is the function of this protein?
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
What are the official names of this protein?
Kynureninase, L-kynurenine hydrolase.
What is the protein family that this protein belongs to?
Belongs to the kynureninase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THII_KLEP3
Sequence: MKFIIKLFPEITIKSQSVRLRFIKILTGNIRNVLKNYDETLAVVRHWDHIEVRAKDENQRPAIRDALTRIPGIHHILEVEDVPFTSLHDIFEKTLPLWREALEGKTFCVRVKRRGKHEFTSIEVERYVGGGLNQHIETARVKLTDPDVTVNLEIENDRLLLVKGRYEGIGGFPIGTQEDVLSLISGGFDSGVSSYMLMRRGCRVHYCFFNLGGAAHEIGVRQVAHYLWNRFGSSHRVRFVAINFEPVVGEILEKVDDGQMGVVLKRMMVRAASKVAERYGVQALVTGEALGQVSSQTLTNLRLIDNVSDTLILRPLISHDKEHIIDLAREIGTEDFARTMPEYCGVISKSPTVKAVKAKIEAEEEHFDFSILDKVVEEASNIDIRDIAQQTEAAVVEVETVTGFGANDAILDIRSIDEQEDKPLKVEGVEVVSLPFYKLSTKFGDLDQSKTWLLWCERGVMSRLQALYLREQGFSNVKVYRP
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_NITOC
Sequence: MRFGVITLFPGMFDALWDSGVVGRALKQGKISLNFWNPRDFAHDRHRTVDARPYGGGPGMVMGIQPLRDAIHVGRAELGKGCRVLYLSPQGRRLDQAGLEALASNESLLFVAGRYEGVDERLIEMEVDEEWSIGDYVLSGGELAAMVIIDGLARLLPGVLGAAESAQQDSFVNGLLDCPHYTRPEVIEGYRVPPVLLSGDHKAIRRWRLKQALGRTWLKRPDLLSRRILDLEQQHLLAEFIREYQAEHREPR
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTCC_STRP6
Sequence: MTQVFQGRSFLAEKDFTRAELEYLIDFSAHLKDLKKRGVPHHYLEGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMFDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVKENFGKLEGLTLVYCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEEEIVTLAEGYAKESGARILITEDADEAVKGADVLYTDVWVSMGEEDKFKERVELLQPYQVNMDLVQKAGNDKLIFLHCLPAFHDTNTVYGKDVAEKFGVKEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLFIPKV
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, catabolic, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIL_AQUAE
Sequence: MRLKELGEFGLIDLIKKTLESKVIGDDTAPVEYCSKKLLLTTDVLNEGVHFLRSYIPEAVGWKAISVNVSDVIANGGLPKWALISLNLPEDLEVSYVERFYIGVKRACEFYKCEVVGGNISKSEKIGISVFLVGETERFVGRDGARLGDSVFVSGTLGDSRAGLELLLMEKEEYEPFELALIQRHLRPTARIDYVKHIQKYANASMDISDGLVADANHLAQRSGVKIEILSEKLPLSNELKMYCEKYGKNPIEYALFGGEDYQLLFTHPKERWNPFLDMTEIGRVEEGEGVFVDGKKVEPKGWKHF
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
What are the official names of this protein?
Thiamine-monophosphate kinase, TMP kinase, Thiamine-phosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-monophosphate kinase family.