PharMolix/UniProtQA huggingface dataset:
Protein: PSD_ZYMMO
Sequence: MNKEEQRKNSAAQSIRWHFPSIHPEGRKFFVIAVIISAIITYFSWLWMAWPLGVLCFCVAAFFRDPIRTVPEGDGLIVSPADGMVCLIADVPPPPELAGADGLGDAPLTRVSIFMSVFDVHINRAPVPGRIARIAYIPGAFVNADLDKASEKNERQHFMIETKEGINVGLTQIAGLIARRIVPLTKVEDYVERGERIGLIRFGSRLDVYLPAGVTPQVALGQRCLAGETILGQIGSQAKPLTGMRL
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: C18AA_PAEPP
Sequence: MNNNFNGGNNTGNNFTGNTLSNGICTKKNMKGTLSRTAIFSDGISDDLICCLDPIYNNNDNNNDAICDELGLTPIDNNTICSTDFTPINVMRTDPFRKKSTQELTREWTEWKENSPSLFTPAIVGVVTSFLLQSLKKQATSFLLKTLTDLLFPNNSSLTMEEILRATEQYVQERLDTDTANRVSQELVGLKNNLTTFNDQVEDFLQNRVGISPLAIIDSINTMQQLFVNRLPQFQVSGYQVLLLPLFAQAATLHLTFLRDVIINADEWNIPTAQLNTYTRYFKEYIAEYSNYALSTYDDGFRTRFYPRNTLEDMLQFKTFMTLNALDLVSIWSLLKYVNLYVSTSANLYNIGDNKVNEGAYPISYGPFFNSYIQTKSNYVLSGVSGIGARFTYSTVLGRYLHDDLKNIITTYVGGTQGPNIGVQLSTTELDELKKQQQATRDSLVDFQFFTLNCMLPNPITAPYFATSLYESRYSSIGGYLRKDVFKSEDSTCGLGNPGAWTSYPDYYITNISATVQINGENTDTTPLYFKENRPITSTRGVNKVIAVYNRKANIAGTNQNGTMIHQAPPDGTGFTVSPLHPSANTITSYIKENYGNSGDSLHLKGQGYLHYMLSGNGQDRYRLVLRLSGAANQIKLQSPTTSIYAFDTSTNNEGITDNGSKFKDFAFSTPFVIPEQKEIVLYFEGVGSLDLMNLIFLPADDTPLY
What is the function of this protein?
Binds to the brush border membrane vesicles of scarab larvae and somehow damages the gut wall to allow the vegetative cells of P. popilliae to enter the hemolymph.  Active on M. melolontha.
What are the official names of this protein?
Parasporal crystal protein Cry18Aa, 79 kDa crystal protein, Crystaline parasporal protoxin, Parasporal delta-endotoxin CryXVIIIA(a).
What is the protein family that this protein belongs to?
Belongs to the delta endotoxin family.
Protein: LOVG_CAEEL
Sequence: MSSQPKLRILCLHGYRQCDQSFRQKTGSTRKLVKSLAEFEFVNGVHSVAVDEHVDSSRAWWFSNNEAMSFSSRESTEVAVGFEESVAAVVKFIEENGPFDGLLGFSQGASMVHLLIAKAQLGEIKLPGIRFAIFFSGFLSLSSKHDSLTLLRIKEFPSMHVFGDADEIVARPKSEKMADMFDVEPLRIAHDGGHVVPSMSKHKEKIAGFMREQLDRKIENN
What are the official names of this protein?
Esterase C25G4.2.
What is the protein family that this protein belongs to?
Belongs to the LovG family.
Protein: GTRB_BPSF5
Sequence: MKISLVVPVFNEEEAIPVFYKTVREFQELKPYEVEIVFINDGSKDATESIINALAVSDPLVVPLSFTRNFGKEPALFAGLDHASGDAVIPIDVDLQDPIEVIPHLIEKWQAGADMVLAKRSDRSTDGRLKRKTAEWFYKLHNKISTPKIEENVGDFRLMSREVVENIKLLPERNLFMKGILSWVGGQTDVVEYVRAERVAGISKFNGWKLWNLALEGITSFSTFPLRVWTYIGLFVASISFLYGAWMIIDTLVFGNPVRGYPSLLVSILFLGGVQLIGIGVLGEYIGRIYIESKHRPKYIIKNEKQK
What is the function of this protein?
Involved in O antigen modification.  Catalyzes the transfer of the glucose residue from UDP-glucose to a lipid carrier.
What are the official names of this protein?
Bactoprenol glucosyl transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. GtrB subfamily.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: RBBP7_CHICK
Sequence: MASKEVLEDTVEERVISEEYKIWKKNTPFLYDLVMTHALEWPSLTVQWLPDVSRPEGKDYALHWLVLGTHTSDEQNHLVVARVQIPNDDQFDTSQYDSEKGEFGGFGSVTGKIETEIKINHEGEVNRARYMPQNPYIIATKTPSADVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSWNSNLKGHLLSASDDHTVCLWDISAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIWQMAENIYNDEEPDIAAAELEGQGT
What is the function of this protein?
Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA.  Component of several complexes which regulate chromatin metabolism.
What are the official names of this protein?
Histone-binding protein RBBP7, Retinoblastoma-binding protein 7, RBBP-7, Retinoblastoma-binding protein p46.
What is the protein family that this protein belongs to?
Belongs to the WD repeat RBAP46/RBAP48/MSI1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL17_MYCLB
Sequence: MPKPTKGPRLGGSSSHQKALLTNLAASLFEHGRIKTTEPKARALRPYAEKLITHAKKGTLHNRREVLKKLPDKDVVHALFAEIGPFFSDRDGGYTRIIKVEARKGDNAPMAVIELVREKTVTSEADRARRVAAASAKAAQAQEKPAQEEEVEATSDEVAYTSEPDKAAEH
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: GLYA_STRPJ
Sequence: MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVMAAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQANCAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAILKQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPVPYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFKEVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQNLLDEVNITLNKNSIPYESLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKNSENEAVLEEVRSAVKELTDAFLLYED
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANC_ACIAC
Sequence: MLIAHSIADLRSALASRGRPAFVPTMGNLHEGHLSLVRQARTLGDVTVASIFVNRLQFLPHEDFDSYPRTWEADRAQLEVAGCDILFAPREADLYPQAQTFKVQPDPLLADLLEGHFRPGFFTGVCTVVMKLFSAVFGTTGGGTALFGKKDYQQLMVIRRMVEQFALPVDIVAGDTCRAPDGLALSSRNGYLGPAERTKAVELARALRTLSDAALSRPVADWPGLEAAASDALRGQGWQPDYLVVRRRADLQRPDTAPRPGTLVALGAARLGSTRLIDNFEF
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REX_GEOTN
Sequence: MSNEQPKIPQATAKRLPLYYRFLKNLHASGKQRVSSAELSEAVKVDPATIRRDFSYFGALGKKGYGYNVNYLLSFFRRTLEEDEVTEVALFGVGNLGTAFLNYNFSKNNNTKIVMAFDVDEQKVGTTVGGVPVYHLDELEERLCGNIPVAILTVPAVAAQALTDRLVTQGIKGILNFTPARLNVPKHIRVHHIDLAIELQSLVYFLRNYPLPS
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UC34_MAIZE
Sequence: SIXEPLALSVFDEP
What are the official names of this protein?
Unknown protein from spot 360 of 2D-PAGE of etiolated coleoptile.
Protein: APYA_EMENI
Sequence: MALHRLKGHGANVGNRVGIQLDKDFVLFQGSEQEALAVYLSGILSLRLKETTTIKYIRLHLRGVRRVSSDTQSSLPARTGRKRFCSENEFYSRTWNFFDGYREAPMTVPAGEYKYPFDVVMEGSLPASVEGMKEASISYLFTVEIGRRHGRDITFDKPLRVIRVPDLEPCSHDFALDEVWANKIAYRIGIQNRTVALGTRIDVDYVFAPLLRDMKIAFIESQLLEVRDLSVEPNDGGSAHAARTETIVCSDRYTLGEEYSSKALESYQFSRTLQLPQALGHCVQDTEDMGVRVSHKLKIHVRMHNPDGHESELRLAIPVLIYLSPYYRVWEDSFCGETIPLPETLNPSDECPPAYGMHELDQLYMPQD
What is the function of this protein?
May be involved in signaling by recognizing appropriately phosphorylated substrates via its arrestin domains and then recruit a HECT-type ubiquitin ligase such as hulA, leading to ubiquitination of the substrate, providing a link between ubiquitination and phosphorylation in protein regulation and stability.
What are the official names of this protein?
HECT-type ubiquitin ligase-interacting protein apyA, Arrestin and PY motif-containing protein A.
What is the protein family that this protein belongs to?
Belongs to the arrestin family.
Protein: BCRH_RICTY
Sequence: MKIIVKIPVWMLLSLFILSPTTETIYTSGLPSLTKYFSIDGCITQITSTLYFLGFAVGILSLGRLSDIYGRRPIVLLGLFIYIVSSIISIFSVNIEMLMIARFIQAFGVSVGSVIGQSMARDSYQGAELSYVYAILSPWLLFIPSLGSYIGGYIIEYSSWHYVFVFFSLIGTILLALYYKILPETNYYIDFSQSSKYFEVFNIIIKDKILWLYAFIIGAFNGIYYGFFIEAPFILIDKMKVLPSFYGKLAFLLSFSAIFGGFLGGYLIKKRQVHDKKVMSIGFIFSLCGCILFVVNAFILEFILVSNGLAISMIFVPMMIHIIGHSLLIPITLRYALEDYAKVTGTAGSIFGAIYYIVIAAVTYCVSKIHGETISNFSLLCLVSSISSVISFYYICILYKKKSIVANEK
What are the official names of this protein?
Uncharacterized transporter RT0591.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Bcr/CmlA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ASST_METAC
Sequence: MVEKSVHEINKKIEDGSVNVVTAEEMVGIVENLGVEGAAREVDVVTTGTFGAMCSSGLMLNLGHSEPPIKIQKLWFNNVEAYSGLAAVDAYLGAAQISDTRGIQYGGAHVIEDLLRGKELDVHATSYGTDCYPRKVLDTRITLDDLNEAVLLNPRNAYQKYAAATNSSKRILNTYMGELLPNFGNVTYSGAGVLSPLSNDPDYETIGMGTRIFMGGAQGYIIGNGTQHSPSSSFGTLMLKGNLKEMSSDYLRAASFAGYGTTLYMGIGIPIPILNEKIAASTAVRDEDIFTDILDYAVGSRDKPVIKQVNYAELRSGSIELEGKNTPTSSLSSFKNARKIANELKEWVKHGKFFVSMPVEKLSREGSAKSMKQTQAVPLVKDVMADFIVTIKKNQTVQDAAKKIWENSFNHLAVVSDTGELVGILTAWDISKAVAENIFDSVESVMTKKVLTCAPNEPVDLAARRLDRYGVSAMPVIDTQRKVLGIITSDNISKLLARRY
What is the function of this protein?
Required for O-acetylhomoserine sulfhydrylase (OAHS)-independent homocysteine (Hcy) biosynthesis (PubMed:25315403, PubMed:25938369).  Together with MA_1822, catalyzes the condensation of sulfide with aspartate semialdehyde to generate homocysteine (Probable).  Likely functions through persulfide intermediate (PubMed:28165724).
What are the official names of this protein?
L-aspartate semialdehyde sulfurtransferase.
What is the protein family that this protein belongs to?
Belongs to the L-aspartate semialdehyde sulfurtransferase family.
Protein: PLSX_UREPA
Sequence: MEKIKILLDTMGYENDLEHVIKAAKDFYYQHEDDLEIILVGNEQLIKPLLDNDWRLFPIVHTEVSIEQNDTILSARKKQNSSMHLALRYLKDKQADGMLTAGNSAVFVYNAYATIGLLEHIKKPAFMPFVPTIDGGVTNLLDVGASIDVDGTDLFNFAIMANTIAKMRTPNPRVGVLNIGTEDHKGLPYHQEANELLKTSNLNYVGFVEPKTILEREVDVLVADGFSGNIALKTMEGVGKTISNFLKNEYKKPKNLFAALLSKPIFKKIKKAFDYKEHAGAFVLGLDGILVKTHGSADYQQFMSALKILYETIKADVLNEIKKDLNNYYGQ
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: UBIA1_MOUSE
Sequence: MAAVQAPGEKINILAGETAKVGDPQKNEWPEQDRLPERSWRHKCASYVLALRPWSFSASLTPVALGSALAYRSQGVLDPRLLLGCAVAVLAVHGAGNLVNTYYDFSKGIDHKKSDDRTLVDRILEPQDVVRFGVFLYTLGCVCAACLYYLSALKLEHLALIYFGGLSGSFLYTGGIGFKYVALGDLVILITFGPLAVMFAYAVQVGSLAIFPLIYAIPLALSTEAILHSNNTRDMESDREAGIVTLAILIGPTFSYVLYNTLLFVPYLIFTILATHCSISLALPLLTIPMAFSLERQFRSQAFNKLPQRTAKLNLLLGLFYVFGIILAPAGSLPRL
What is the function of this protein?
Prenyltransferase that mediates the formation of menaquinone-4 (MK-4) and coenzyme Q10.  MK-4 is a vitamin K2 isoform required for endothelial cell development.  Mediates the conversion of phylloquinone (PK) into MK-4, probably by cleaving the side chain of phylloquinone (PK) to release 2-methyl-1,4-naphthoquinone (menadione; K3) and then prenylating it with geranylgeranyl pyrophosphate (GGPP) to form MK-4.  Also plays a role in cardiovascular development independently of MK-4 biosynthesis, by acting as a coenzyme Q10 biosynthetic enzyme: coenzyme Q10, also named ubiquinone, plays an important antioxidant role in the cardiovascular system.  Mediates biosynthesis of coenzyme Q10 in the Golgi membrane, leading to protect cardiovascular tissues from NOS3/eNOS-dependent oxidative stress.
What are the official names of this protein?
UbiA prenyltransferase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Mitochondrion.
Protein: VAPB2_PYRAB
Sequence: MSKTITIADDVYYELVKMKGNKSFSELLRELIGKKKKGNLDILMIAFGTMSEEEVKEFKKKIKEVEEWINSWTPVS
What is the function of this protein?
Possibly the antitoxin component of a type II toxin-antitoxin (TA) system.  Its cognate toxin is VapC2 (Potential).
What are the official names of this protein?
Putative antitoxin VapB2.
What is the protein family that this protein belongs to?
Belongs to the UPF0330 family.
Protein: PCKG_PYRFU
Sequence: MMNEALKKLEELLDKDQFEKIKAINNPYLHSFLAEWIQWLEPSKVYVCTDSEEDEEYVRWKALYYGEERMLEMVRHTVHYDNYYDQARDKQNTKLLVPKGTNLPFLNTMDREDGLREIREIMKGIMRGKELFIGFFVLGPKNSVFTIPAVQLTDSAYVMHSEFLLYRKGYEEFKRLGPTKNFLKFVHSAGELDERKTSKNLDKRRIYIDLVDETVYSANTQYGGNVIGLKKLAFRLTIQRAVREGWLSEHMFLMRVNGPNGRKTYFTGAYPSMCGKTSTAMIPWENIVGDDLVFIKNLDGVARAVNVEIGVFGIIEGINQKDDPIIWQVLHSPVEIIFSNVLVKDGKPYWNGMGIEIPDEGENHSGKWWRGKRDAEGKEIPPSHKNARFTVRLEAFPNLDREALENPCGVEVGGMIFGGRDPDTWPPVRESFNWDHGVITMGAALESETTAATLGKEGVRAFNPMSILDFLSVHIGDYLRNYLEFGRKLKKTPKIFAVNYFLRENGQWLNEKLDKAVWLKWMELRVHNDVGAIETPIGYIPRYEDLKVLFRQVLNKDYSREDYEKQFKIRVPELLAKIDRIWKIYEPIDNIPEELFQELEKERKRILEAREKYGDYISPFALEK
What is the function of this protein?
Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase [GTP], PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPF_SINFN
Sequence: MKMDVKICGLKTAEAVEHAVSLGASHTGFIFFPKSPRNIEPDDAGRLAERIRGRAKIVAVTVDADNDDLDEIVSALKPDILQLHGGEDPERVLTVKAIYGLPVMKALSIREASDLDRIDPYLGIVDRFLFDAKPPAGSELPGGNGVSFDWRLLDALDGSVDYMLSGGLNAENIGEALALTGARAVDTSSGVESAPGVKDLKLMDAFFDAVRRAEAVRPRSGSKT
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: PNDA2_ECOLX
Sequence: MPQRTFLMMLIVICVTILCFVWMVRDSLCGLRLQQGNTVLVATLAYEVKR
What is the function of this protein?
Toxic component of a type I toxin-antitoxin (TA) system (By similarity).  When expressed is involved in cellular Mg(2+) release and degradation of stable RNA (PubMed:3328043).
What are the official names of this protein?
Protein PndA.
What is the protein family that this protein belongs to?
Belongs to the Hok/Gef family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RS4_THEFY
Sequence: MRYTGPKVRLSRRAGVPLTRKAVKYFEKRPYPPGEHGRRVRRSTSDYAVRQAEKQKLRWYYDLSEKQLARVYENAKKRPGRTGEEMIAELELRLATVLLRAGFAASIYAARQFINHGHITVDGKKVDIPSYQVKPGQIVSVREKSRKLVPFIEAAEGVHADEKIASYLAVSHKDLTIAVVDRPKREQVPVPFDEQLVVEYYAR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: MURA_YERPA
Sequence: MDKFRVQGRTRLSGEVTISGAKNAALPILFAALLAEEPVELQNVPKLKDIDTTIKLLSQLGTKIERNNGSVFVDASAVNEFCAPYDLVKTMRASIWALGPLVARFGQGQVSLPGGCAIGARPVDLHITGLEQLGAEIKLEEGYVKASVNGRLKGAHIVMDKVSVGATVTIMSAATLAEGTTVIENAAREPEIVDTANFLNTLGAKISGAGTDRITIEGVTRLGGGVYRVLPDRIETGTFLVAAAISGGKVVCRQTRPDTLDAVLAKLREAGADIEVGDDWISLDMQGKRPKAITFRTAPHPGFPTDMQAQFSLLNLVAEGTGVITETIFENRFMHVPELIRMGAHAEIESNTVICYGVEQLSGAQVMATDLRASASLVLAGCIAEGVTIVDRIYHIDRGYERIEDKLRALGAKIERVKGE
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSH1_BDEBA
Sequence: MRSTQKTLALWFFLIIMAVFLFQAYESKQQKAIADFNFSKFTEAVKAGEVATVTFRQDTSEVVGEMKPEFEKKYNGTHFSIVGNTQDEGYKFLQQHGITPNYERADNGGFFQSLLVNWLPLILIVAMFLFIMRQIQAGGGKAMSFGKSRARLLTEHKNRVTFKEVAGVDEAKEDLQEIVSFLKDPKKYTKLGGRIPKGVLLVGSPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVGASRVRDLFEQGKKNAPCLIFIDEIDAVGRHRGAGMGGGHDEREQTLNQLLVEMDGFESSEGVIMIAATNRPDVLDPALLRPGRFDRRVIVNKPDLKGREQILAVHMRKTPLGPDVDASKIARGTPGFSGADLENLVNEAALVAARSDKKYLEMEDFEKAKDKVTMGAERRSMVISDEDKKVTAYHEAGHTLVGKKLVGLDPIHKVTIIPRGMALGVTQTLPEKESVSLSKSKAENMIAFLFGGRAAEELIFKDITTGAGNDIERATEIARRMVCEWGMSKLGPLAYETRDNPVFMGMGYGNKSKEYSDAKAQEIDTEVEKIIKHGYDISIQILRDHQDALERLTQALLEYETIDGHEVDMLVNGAAVAEIEKYRNAKKDSNAAIMNAAEKKGSGDPVGNTGPVTI
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH 1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: KCTD7_MOUSE
Sequence: MVVVTGREPDSRHSDGAMSSSEAEDDFLEPATPTATQAGHGLPLLPQEFPEVVPLNIGGAHFTTRLSTLRRYEDTMLAAMFSGRHYIPTDSEGRYFIDRDGTHFGDVLNFLRSGDLPPREHVRAVHKEAQYYAIGPLLEQLENMQPLKGEKVRQAFLGLMPYYKDHLERIVEIARLRAVQRKARFAKLKVCVFKEEMPITPYECPLLNSLRFERSESDGQLFEHHCEVDVSFGPWEAVADVYDLLHCLVTDLSAQGLTVDHQCIGVCDKHLVNHYYCKRPIYEFKITWW
What is the function of this protein?
May be involved in the control of excitability of cortical neurons.
What are the official names of this protein?
BTB/POZ domain-containing protein KCTD7.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm, cytosol.
Protein: PYRB_DEHMC
Sequence: MTHIPKTPADTETLLSEVQGWKHRHVLDLDNFSREELDMVMQTAGVMLDILSRPVKKVPALKGKTIATLFYEPSTRTRSSFELAAKSLSADVLNLNVSQSSISKGESLLDTLDTLESLGADMVVMRHPLSGAPYLAANNCHANIINAGDGWHAHPSQALLDIFTILRHKSSLEGLKITLIGDIKHSRVAHSNIWGLSKMGAKITLCAPYTLLPEGLNTNSKIFPEVTLETDIKQAVSGADVVMGLRLQRERQQSGLLPGIREYARYFQLNEEILKLAKPNSLVMHPGPVNEDIELSQSVVHGEQSVINEQVKNGVAVRMALFYLCSGSKEI
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: B3GA2_CANLF
Sequence: MKSALFSRFFILLPWILIVIIMLDVDTRRPAPPLTPRPYFSPYAVGRGGARLPPRRGGPDSGPGRGWEKRNESRPHARPRPEPPLPTIYAITPTYSRPVQKAELTRLANTFRQVAQLHWILVEDAAARSELVSRFLARAGLPSTHLHVPTPRRYKRPGLPRATEQRNAGLAWLRQRHQHQRAQPGVLFFADDDNTYSLELFQEMRTTRKVSVWPVGLVGGRRYERPLVENGKVVGWYTGWRADRPFAIDMAGFAVSLQVILSNPKAVFKRRGSQPGMQESDFLKQITTVEELEPKANNCTKVLVWHTRTEKVNLANEPKYRLDTVKIEV
What is the function of this protein?
Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on both glycolipids and glycoproteins.
What are the official names of this protein?
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2, Beta-1,3-glucuronyltransferase 2, GlcAT-D, UDP-glucuronosyltransferase S, GlcAT-S, Glucuronosyltransferase S.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 43 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: GLYA_LEPBJ
Sequence: MQFLPKADPEIFAALKKEDERQENNLEMIASENFVSRAVLEAYTSTLTNKYAEGYPGKRYYNGCHNADIVESLAIERAKELFGAEYANVQPHSGAQANMAVFLACLEPGDSFLGMNLAHGGHLTHGSPVNVSGRIYKPIPYGVDSKTETIDYDEIAKLAREHKPKLIVAGASAYARTIDFSKFAEIAKEVGAKLMADIAHISGLVSTGYHPSPVGLFDFVTTTTHKTLRGPRGGLILSTLENEKVLNSRVFPGIQGGPLMHVIAAKAVAFKEALQPEYKKYIEIVLANAKTLAEVFLKRGYRVVSGGTDNHLVLLDVSVKGLTGVQAADGLDEVGVTVNKNAIPFDKNPPAVASGIRLGTPALTTRGLKPADMETVGNLICDFLDNPNEEKNKKRVKGGVQEITRKFPMDQFRLD
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_CHLAD
Sequence: MATGTDFFDQATIVVRAGNGGNGAATFRREKYVPRGGPNGGDGGRGGHVYLIADPEYNTLLHFRYQRKFVAENGGHGGKNAMHGRNGADVYVPVPPGTVVRATINGVTYTVDLARPGQRLLAARGGRGGLGNIHFTTPTRQAPRLAELGEPGQELTLELELKMLADVGLVGFPNAGKSTLLSVISAARPKIAAYPFTTLTPNLGIVEVGVQRFVVADIPGLIEGAHAGVGLGHDFLRHIERTRLLIHIIDAAGVDGRTPWDDYEQINTELRLYQPELAQRKQVVALNKADLPAAQANLPILRERLPVAPEDLFVISAATRAGIEPLLQRVAELLRADPPPQRDPVDPDEPPLEWPLPPVDENAFTVEREGDAFRVRGVKIERLIAMSNLEQDEAIDRIQRVLEASGINEALMAAGVQDGDVVRIGRAELVWDDSGQHAL
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_BACTN
Sequence: MARYTGPKSRIARKFGEGIFGADKVLSKKNYPPGQHGNSRKRKTSEYGVQLREKQKAKYTYGVLEKQFRNLFEKAATAKGITGEVLLQLLEGRLDNVVFRLGIAPTRAAARQLVSHKHITVDGEVVNIPSFAVKPGQLIGVRERSKSLEVIANSLAGFNHSKYAWLEWDETSKVGKMLHIPERADIPENIKEHLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: SIR5_CHICK
Sequence: MCLAQCAARRLLAQVHGALKPAPKKPNWCWEMARPSSNMADFREVFAKAKHIAIITGAGVSAESGVPTFRGAGGFWRKWQAQELATPGAFARNPSRVWEFYHYRREVMLSKHPNAAHIAIAECEKRLRKQGRSVVVITQNIDELHRKAGTKHLLEIHGSLFKTRCTNCGNVTANYKSPICPALAGKGAPDPEIEDAAIPVEELPQCEEDGCHGLLRPHVVWFGETLDPDVLTEVEKELDLCDLCLVVGTSSVVYPAAMFAPQVSARGVPVAEFNMEATPATDRFRFHFEGPCGTTLPPALARHESEIIA
What is the function of this protein?
NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins.  Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.
What are the official names of this protein?
NAD-dependent protein deacylase sirtuin-5, mitochondrial, Regulatory protein SIR2 homolog 5.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class III subfamily.
What are the subcellular locations of this protein?
Mitochondrion. Cytoplasm, cytosol. Nucleus. Note=Mainly mitochondrial. Also present extramitochondrially, with a fraction present in the cytosol and very small amounts also detected in the nucleus.
Protein: RS28A_SCHPO
Sequence: MDSSKVPVKLAKVIKVLGRTGSRGGVTQVRVEFMDDTSRSIIRNVKGPVREDDILVLLESEREARRLR
What are the official names of this protein?
40S ribosomal protein S28-A, S33.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS28 family.