PharMolix/UniProtQA huggingface dataset:
Protein: MSRA_STRMU
Sequence: MERAIFAGGCFWCMVQPFEEQDGILSVRSGYTGGHVVNPTYEQVCSKMTGHTEAVEIIFDESKISYADLVEIYWRQTDPTDSFGQFEDRGDNYRPVIFYFDEQQRKIAEQSKANLQASGHFNRPIVTTIEAAQPFYEAEKDHQAFYRKNPERYARSSAIRHHFLKENWS
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: DDL_LEGPC
Sequence: MSKPVNLVLLYGGKSGEHEVSLVSAASVLKHLDSEKYHIIPIAMDKSGRFHRHDYNDLLACSDKLPVVTEKSTPLEGLLINGRLAVDAEIVFPVVHGPLYEDGCLQGLLELAGVAYVGCDVLSSAIGMDKDMARRLACINGLKSARYKLLSWHANASERQQFCHEVASEFGWPLFVKPCSLGSSVGIHKANNMDELNAAVADALRYDEEILVEEFIVGREIELAVLENSIPCGKPRVSMVGEIKVNHPDGYYSYTAKYLESSQTDLIIPAQLNNSLEEQLKQAAANIFSYLKCKGMARVDFFVNDKTEEIYFNEINTLPGFTSISMYPKLWQATGVAYPDLLDELINLAMVHHNCRQHLVTNYL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTMRA_HUMAN
Sequence: MFSLKPPKPTFRSYLLPPPQTDDKINSEPKIKKLEPVLLPGEIVVNEVNFVRKCIATDTSQYDLWGKLICSNFKISFITDDPMPLQKFHYRNLLLGEHDVPLTCIEQIVTVNDHKRKQKVLGPNQKLKFNPTELIIYCKDFRIVRFRFDESGPESAKKVCLAIAHYSQPTDLQLLFAFEYVGKKYHNSANKINGIPSGDGGGGGGGGNGAGGGSSQKTPLFETYSDWDREIKRTGASGWRVCSINEGYMISTCLPEYIVVPSSLADQDLKIFSHSFVGRRMPLWCWSHSNGSALVRMALIKDVLQQRKIDQRICNAITKSHPQRSDVYKSDLDKTLPNIQEVQAAFVKLKQLCVNEPFEETEEKWLSSLENTRWLEYVRAFLKHSAELVYMLESKHLSVVLQEEEGRDLSCCVASLVQVMLDPYFRTITGFQSLIQKEWVMAGYQFLDRCNHLKRSEKESPLFLLFLDATWQLLEQYPAAFEFSETYLAVLYDSTRISLFGTFLFNSPHQRVKQSTEFAISKNIQLGDEKGLKFPSVWDWSLQFTAKDRTLFHNPFYIGKSTPCIQNGSVKSFKRTKKSYSSTLRGMPSALKNGIISDQELLPRRNSLILKPKPDPAQQTDSQNSDTEQYFREWFSKPANLHGVILPRVSGTHIKLWKLCYFRWVPEAQISLGGSITAFHKLSLLADEVDVLSRMLRQQRSGPLEACYGELGQSRMYFNASGPHHTDTSGTPEFLSSSFPFSPVGNLCRRSILGTPLSKFLSGAKIWLSTETLANED
What are the official names of this protein?
Myotubularin-related protein 10, Inactive phosphatidylinositol 3-phosphatase 10.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
Protein: SOTB_ECOLC
Sequence: MTTNTVSRKVAWLRVVTLAVAAFIFNTTEFVPVGLLSDIAQSFHMQTAQVGIMLTIYAWVVALMSLPFMLMTSQVERRKLLICLFVVFIASHVLSFLSWSFTVLVISRIGVAFAHAIFWSITASLAIRMAPAGKRAQALSLIATGTALAMVLGLPLGRIVGQYFGWRMTFFAIGIGALITLLCLIKLLPLLPSEHSGSLKSLPLLFRRPALMSIYLLTVVVVTAHYTAYSYIEPFVQNIAGFSANFATALLLLLGGAGIIGSVIFGKLGNQYASALVSTAIALLLVCLALLLPAANSEIHLGVLSIFWGIAMMIIGLGMQVKVLALAPDATDVAMALFSGIFNIGIGAGALVGNQVSLHWSMSMIGYVGAVPAFAALIWSIIIFRRWPVTLEEQTQ
What is the function of this protein?
Involved in the efflux of sugars.  The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites.
What are the official names of this protein?
Probable sugar efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FLIE_SHISS
Sequence: MSAIQGIEGVISQLQATAMSARAQESLPQPTISFAGQLHAALDRISDTQTAARTQAEKFTLGEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV
What are the official names of this protein?
Flagellar hook-basal body complex protein FliE.
What is the protein family that this protein belongs to?
Belongs to the FliE family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: HSP1_GALVR
Sequence: MARYRCCRSRSRCRRRRRSCRRRRRCRRRRARRSCRRRYSLRCCRRY
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex (By similarity).
What are the official names of this protein?
Sperm protamine P1.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: KIN2_ARATH
Sequence: MSETNKNAFQAGQAAGKAEEKSNVLLDKAKDAAAAAGASAQQAGKSISDAAVGGVNFVKDKTGLNK
What are the official names of this protein?
Stress-induced protein KIN2, Cold-induced protein COR6.6.
Protein: RIMO_DEIGD
Sequence: MTRTQEPLPTVAAPKVGFISLGCPKALVDSERILTQLRAEGYEVAPNYEDAQAVIVNTCGFITPAVEESLSAIGEALDATGKVIVTGCLGERPEKILERHPKVAAITGSEAVDDVMAHVRELLPIELDPFTGLLPVAAPGMRQGDTLAPSVKLTPRHYAYVKIAEGCNHTCSFCIIPKLRGRQVSRDAGAVLYEAYRLIAGGTKELMIISQDTSAYGVDLRHRTSEFQGEQVRAHLIDLAEKLGEMGAWVRMHYVYPYPHVERIVELMSQGKILPYLDVPLQHASPAVLKRMRRPGAGKQLDTIRRWREICPELVIRSTFIVGFPGETEEDFQLLLDFLEEARLDRVGAFTYSDVEEADANALDGAIPEEVKQERLARFMEVAQRISREKLAEKVGRVLDVIIDEFNDDEGDEPGTRLIGRTKGDAPGIDGQVYLYAGDFAGQVKIGDIVQARIEDSDEYDLYGEVIHTPEWRPNVPLLGHFGKH
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S2539_DANRE
Sequence: MGDRPAVRISAAITPVQQMLASGTGAVLTSLFVTPLDVVKIRLQAQQTPLFQAIAAESRPWFRVTRPSKWKCFLYCNGLMDHVYVCQNMSSCSNLYKTSTHFSGTLDAFVKITHNEGLRSLWSGLPPTLVMAVPATVIYFTCYDQLRDFLCYSMGYHGDHIPLIAGGLARLGAVSVISPLELVRTKMQSRRLQYSELMVCIRSSVAQDGWLSLWRGWGPTVLRDVPFSALYWFNYELVKAQLCEHYRTPQASFTISFTAGAVSGAIAAVLTLPFDVVKTRRQIQLGEMEALGAVSMKKPSSTWNMMRNIWIDMGYKGLFAGFLPRVIKVAPACAVMISTYEFGKTFFQERNLHQARCGL
What is the function of this protein?
Mitochondrial transporter required for glutathione import into mitochondria.  Glutathione, which plays key roles in oxidative metabolism, is produced exclusively in the cytosol and is imported in many organelles.  Mitochondrial glutathione is required for the activity and stability of proteins containing iron-sulfur clusters, as well as erythropoiesis (By similarity).  Involved in the early steps of heme biosynthesis (PubMed:19656490).
What are the official names of this protein?
Probable mitochondrial glutathione transporter SLC25A39, Solute carrier family 25 member 39.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: FLGA_YEREN
Sequence: MNRNGVITCALGGLLLSQAATHQAMAADLSVQVNQFFQQQYPDKESQVKVVIKTPQNQWPQCDMPEITLPANARPWGNISLSVRCDGVRRFIQTQVQVSGHYAVAARQLAAGEKMTLQDIKMKQGRLDTLPPGALLEPNFAQGAVSLRQINAGQPLTRNMLRRLWIIKAGQDVQVLALGEGFNVNSNGKAMNNAAIQDNVRVRMASGQIVSGTVADDGTVHILL
What is the function of this protein?
Involved in the assembly process of the P-ring formation.  It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly (By similarity).
What are the official names of this protein?
Flagella basal body P-ring formation protein FlgA.
What is the protein family that this protein belongs to?
Belongs to the FlgA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: SPRT_ECODH
Sequence: MKTSRLPIAIQQAVMRRLREKLAQANLKLGRNYPEPKLSYTQRGTSAGTAWLESYEIRLNPVLLLENSEAFIEEVVPHELAHLLVWKHFGRVAPHGKEWKWMMENVLGVPARRTHQFELQSVRRNTFPYRCKCQEHQLTVRRHNRVVRGEAVYRCVHCGEQLVAK
What are the official names of this protein?
Protein SprT.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_MYCTA
Sequence: MAVKIKLTRLGKIRNPQYRVAVADARTRRDGRAIEVIGRYHPKEEPSLIEINSERAQYWLSVGAQPTEPVLKLLKITGDWQKFKGLPGAQGRLKVAAPKPSKLEVFNAALAAADGGPTTEATKPKKKSPAKKAAKAAEPAPQPEQPDTPALGGEQAELTAES
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: FBRL_ASHGO
Sequence: MAFQPGSRGGRGGARGGARGGARGGRGGFGGRGGSRGGRGGFDSRGGARGGFGGRGGSRGGPRGGPRGGARGGRGGARGGAKGGAKVVIEPHKHAGVFIARGKEDLLVTKNVAPGESVYGEKRISVEEPASEEGVPPTKVEYRVWNPFRSKLAAGIMGGLDELFIAPGKKVLYLGAASGTSVSHVADVVGPEGLVYAVEFSHRPGRELISMAKKRPNVIPIIEDARHPQKYRMLIGMVDAVFADVAQPDQARIIALNSHMFLKDQGGVVISIKANCIDSTVDAETVFAREVQKLREEKIKPLEQLTLEPYERDHCIVIGRYMRSGL
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins.  Involved in pre-rRNA processing.  Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA.  Site specificity is provided by a guide RNA that base pairs with the substrate.  Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.  Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ105me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus (By similarity).
What are the official names of this protein?
rRNA 2'-O-methyltransferase fibrillarin, Histone-glutamine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Fibrillarin family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Note=Fibrillar region of the nucleolus.
Protein: YYAB_BACSU
Sequence: MVYQTKRDVPVTLMIVFLILLIQADAIVPFVLGNMRVSGWIIFILLTLLNGLIIWSFIDLKYVLKEHHLIIKAGLIKHQIPYENIDKVVQKKKLWSGFRLIGSRHAITIYYQGGWGHAVISPQKSEEFIHKLKEKNSNIIIFTKSK
What are the official names of this protein?
Uncharacterized protein YyaB.
Protein: MUTS_PSEFS
Sequence: MSKNTSDLSSHTPMMQQYWRLKNQHPDQLMFYRMGDFYEIFYEDAKKAAKLLDITLTARGQSAGQSIPMCGIPYHSLEGYLVKLVKLGESVVICEQIGDPATSKGPVERQVVRIITPGTVSDEALLDERRDNLIAAVLGDERLFGLSVLDITSGNFSVLEIKGWENLLAELERINPVELLIPDDWPKDLPAEKRRGTKRRAPWDFERDSALKSLCQQFSVQDLKGFGCETLTLAIGAAGCLLGYAKETQRTALPHLRSLRHERLDDTVVLDGASRRNLELDTNLAGGRDNTLQSVVDRCQTAMGSRLLTRWLNRPLRDLTVLQARQTSITCLLDGYRFEKLQPQLKEIGDIERILARIGLRNARPRDLARLRDALGALPQLQVAMTELDTPHLQQLAVTAGTYPELAALLEKAIIDNPPAIIRDGGVLKTGYDSELDELQSLSENAGQFLIDLEAREKARTGLANLKVGYNRVHGYFIELPSKQAESAPIDYQRRQTLKGAERFITPELKAFEDKALSAKSRALAREKMLYEALLEDLISQLAPLQDTAAALAELDVLSNLAERALNLDLNCPRFVSEPCMRIVQGRHPVVEQVLTTPFVANDLSLDDDTRMLVITGPNMGGKSTYMRQTALIVLLAHIGSFVPAASCELSLVDRIFTRIGSSDDLAGGRSTFMVEMSETANILHNATERSLVLMDEVGRGTSTFDGLSLAWAAAERLAHLRAYTLFATHYFELTVLPESEPLVTNVHLNATEHNERIVFLHHVLPGPASQSYGLAVAQLAGVPNDVITRAREHLSRLETTALPHETVVASPTKATSKPAAPHQSDMFASLPHPVLDELAKLDLDGLTPRKALEMLYALQVRI
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: HRI1_YEAST
Sequence: MPALLKRLLFQVGPHPNERTFTLSSVSTDGHYISLRPFVKPSGDELSFPFEWAFAGTNETVKANDQGNGVVTQDFNFWLDTNVYLNVPNTHRGEVNTTWKNWDSGCVEETGAVYPFGADKESVSFRELWQPVDPSREDLVIVSPNNEKFSSNARSIVLKVTDEAYDGLVIVIGRWIQGFLSQKNNNTIEGLNFIRLLEKDSGKSEFLLSYGKEVNKIPQSYENLKKGSTVTSNGLNWEVIEYHA
What is the function of this protein?
Unknown.  Non essential.
What are the official names of this protein?
Protein HRI1, HRR25-interacting protein 1.
What is the protein family that this protein belongs to?
Belongs to the HRI1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MUP_RATRT
Sequence: LCVAHGITREKIEENGSMRENIIDVTKTNRVFMQHIDVLENSLGFK
What is the function of this protein?
Binds pheromones that are released from drying urine of males.  These pheromones affect the sexual behavior of females (By similarity).  Acts as a shuttle for pheromonal communication between individuals of the same species.
What are the official names of this protein?
Major urinary protein, MUP, Alpha(2)-euglobulin, Alpha-2u-globulin.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted.
Protein: DPS_SALCH
Sequence: MSTAKLVKTKASNLLYTRNDVSESDKKATVELLNRQVIQFIDLSLITKQAHWNMRGANFIAVHEMLDGFRTALTDHLDTMAERAVQLGGVALGTTQVINSKTPLKSYPLDIHNVQDHLKELADRYAVVANDVRKAIGEAKDEDTADIFTAASRDLDKFLWFIESNIE
What is the function of this protein?
During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages.  It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction.  One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.
What are the official names of this protein?
DNA protection during starvation protein.
What is the protein family that this protein belongs to?
Belongs to the Dps family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGP1_HUMAN
Sequence: MSRSRASIHRGSIPAMSYAPFRDVRGPSMHRTQYVHSPYDRPGWNPRFCIISGNQLLMLDEDEIHPLLIRDRRSESSRNKLLRRTVSVPVEGRPHGEHEYHLGRSRRKSVPGGKQYSMEGAPAAPFRPSQGFLSRRLKSSIKRTKSQPKLDRTSSFRQILPRFRSADHDRARLMQSFKESHSHESLLSPSSAAEALELNLDEDSIIKPVHSSILGQEFCFEVTTSSGTKCFACRSAAERDKWIENLQRAVKPNKDNSRRVDNVLKLWIIEARELPPKKRYYCELCLDDMLYARTTSKPRSASGDTVFWGEHFEFNNLPAVRALRLHLYRDSDKKRKKDKAGYVGLVTVPVATLAGRHFTEQWYPVTLPTGSGGSGGMGSGGGGGSGGGSGGKGKGGCPAVRLKARYQTMSILPMELYKEFAEYVTNHYRMLCAVLEPALNVKGKEEVASALVHILQSTGKAKDFLSDMAMSEVDRFMEREHLIFRENTLATKAIEEYMRLIGQKYLKDAIGEFIRALYESEENCEVDPIKCTASSLAEHQANLRMCCELALCKVVNSHCVFPRELKEVFASWRLRCAERGREDIADRLISASLFLRFLCPAIMSPSLFGLMQEYPDEQTSRTLTLIAKVIQNLANFSKFTSKEDFLGFMNEFLELEWGSMQQFLYEISNLDTLTNSSSFEGYIDLGRELSTLHALLWEVLPQLSKEALLKLGPLPRLLNDISTALRNPNIQRQPSRQSERPRPQPVVLRGPSAEMQGYMMRDLNSSIDLQSFMARGLNSSMDMARLPSPTKEKPPPPPPGGGKDLFYVSRPPLARSSPAYCTSSSDITEPEQKMLSVNKSVSMLDLQGDGPGGRLNSSSVSNLAAVGDLLHSSQASLTAALGLRPAPAGRLSQGSGSSITAAGMRLSQMGVTTDGVPAQQLRIPLSFQNPLFHMAADGPGPPGGHGGGGGHGPPSSHHHHHHHHHHRGGEPPGDTFAPFHGYSKSEDLSSGVPKPPAASILHSHSYSDEFGPSGTDFTRRQLSLQDNLQHMLSPPQITIGPQRPAPSGPGGGSGGGSGGGGGGQPPPLQRGKSQQLTVSAAQKPRPSSGNLLQSPEPSYGPARPRQQSLSKEGSIGGSGGSGGGGGGGLKPSITKQHSQTPSTLNPTMPASERTVAWVSNMPHLSADIESAHIEREEYKLKEYSKSMDESRLDRVKEYEEEIHSLKERLHMSNRKLEEYERRLLSQEEQTSKILMQYQARLEQSEKRLRQQQAEKDSQIKSIIGRLMLVEEELRRDHPAMAEPLPEPKKRLLDAQERQLPPLGPTNPRVTLAPPWNGLAPPAPPPPPRLQITENGEFRNTADH
What is the function of this protein?
Major constituent of the PSD essential for postsynaptic signaling.  Inhibitory regulator of the Ras-cAMP pathway.  Member of the NMDAR signaling complex in excitatory synapses, it may play a role in NMDAR-dependent control of AMPAR potentiation, AMPAR membrane trafficking and synaptic plasticity.  Regulates AMPAR-mediated miniature excitatory postsynaptic currents.  Exhibits dual GTPase-activating specificity for Ras and Rap.  May be involved in certain forms of brain injury, leading to long-term learning and memory deficits (By similarity).
What are the official names of this protein?
Ras/Rap GTPase-activating protein SynGAP, Neuronal RasGAP, Synaptic Ras GTPase-activating protein 1, Synaptic Ras-GAP 1.
Protein: AGLK_RHIME
Sequence: MTGLLLKDIRKSYGAVDVIHGIDLDIKEGEFVVFVGPSGCGKSTLLRMIAGLEEITGGDMFIDGERVNDVPPSKRGIAMVFQSYALYPHMTVYDNMAFGMRIARESKEEIDRRVRGAADMLQLTPYLDRLPKALSGGQRQRVAIGRAICRNPKVFLFDEPLSNLDAALRVATRIEIAKLSERMSDTTMIYVTHDQVEAMTLADRIVVLSAGHIEQVGAPLELYERPANLFVARFIGSPAMNVIPATITATGQQTAVSLAGGKSVTLDVPTNASENGKTASFGVRPEDLRVTEADDFLFEGTVSIVEALGEVTLLYIEGLVENEPIIAKMPGIARVGRGDKVRFTADKAKLHLFDTNGQSYRA
What is the function of this protein?
Part of the binding-protein-dependent transport system for alpha-glucosides such as sucrose, maltose and trehalose.  Probably responsible for energy coupling to the transport system.
What are the official names of this protein?
Alpha-glucoside transport ATP-binding protein AglK.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y1808_ARCFU
Sequence: MKAGSIASSPGKLKIMNLLAKKELDAGRIAKSTRIPLNIVKWLLDELEKDGLVEQEAGSYKATEEGIKALKALKM
What are the official names of this protein?
Uncharacterized protein AF_1808.
Protein: TMLH_CHICK
Sequence: MWCRRLACLLSVPCQHTRHRLLGPSCGRRTFTAAVARWHHTAPESLSCAWQLHGDHLELRYADTLMRFDFVWLRDHCRSASCYNAKTNQRSLDTASVDLSIKPKAVRVDETTLFLTWPDGHVTRYGLQWLVKNSYEGQKQQVMHPRILWNAEIYRQAQVPSVDCQSFLETDEGLKEFLQNFLLYGIAFVENVTPTKEDTQILAERISLIRETIYGRMWYFTSDFSRGDTAYTKLALDRHTDTTYFQEPCGIQVFHCLKHEGTGGRTLLVDGFYAAEQVLRQAPDQFELLSKVPLKHEYIENVGDCHNHMIGVGPVLNVYPWNNELYLIRYNNYDRAVINTVPYDVVNRWYTAHRTLTTELRRPENELWVKLKPGKALFIDNWRVLHGREAFTGYRQLCGCYLTRDDVLNTARLLGLQA
What is the function of this protein?
Converts trimethyllysine (TML) into hydroxytrimethyllysine (HTML).
What are the official names of this protein?
Trimethyllysine dioxygenase, mitochondrial, Epsilon-trimethyllysine 2-oxoglutarate dioxygenase, TML hydroxylase, TML-alpha-ketoglutarate dioxygenase, TML dioxygenase, TMLD.
What is the protein family that this protein belongs to?
Belongs to the gamma-BBH/TMLD family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: YCIB_VIBCH
Sequence: MKQLLDFIPLIIFFALYKFYDIYVATGALIAATTVQVIVTYAMYKKVEKMQLITFVMVALFGGMTLALHDDNFIKWKVTIVYVVFALGLTISQIMGKPAIKGMLGKELTLPDAVWSTINWAWVMFFSGCAALNLYVAYHLPLDVWVNFKVFGLLAATLVFTLLTGGYIYKHLPHEPKQKNQ
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GPDA_CUPTR
Sequence: MKLTFLGAGAWGTALASHAAATNDVVLWGRDPAQLGAIAATHENAAYLPGVKLSARLAVQADFELAVAHAADDPDGIVVVATPVAGLREMTRRLAARSARPVSMLWLCKGFEAGTHLLPHQMVRAELDAAGRTEGFAYGVLSGPSFAREVAQGLPCALTVAGTEPSLADRAQAAFHHHAMRIYGSDDLTGVEVGGAVKNVLAIATGASDGLGLGLNARAALVTRGLAEMTRLGLALGGRVETFMGLAGVGDLILTATGDLSRNRKVGQQLASGQSLEQVLAGLGHVAEGVRCAQAVAELAATHGIEMPIARAVCAVLFDGLSAADAVAQLLQRDARDE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR9_AGRFC
Sequence: MAVVSKKIPAPDKVKIRTALLSVSDKTDIIELATVLSKLGVKLLSTGGTAKAIAEAGLAVTDVSDVTNFPEIMDGRVKTLHPNVHGGLLAIRDDAEHVEAMKAHGIEAIDLSVINLYPFEEVRAKGGDYPTTVENIDIGGPAMIRASAKNHAYVTVVTDPSDYPALVEALQADDGQTSYALRQRFAAKAYARTAAYDAVISNWFAEALAIETPHYRAIGGVLKEKMRYGENPHQSAGFYLTGEKRPGVATATLLQGKQLSYNNINDTDAAYELVAEFLPENAPAVAIVKHANPCGVATGPTLAEAYRRALACDSVSAFGGVIALNRTLDAETAEEIVKLFTEVIIAPDVTEEAKSIIARKPNLRLLAAGGLPDPRAAGLTAKTVSGGLLVQSRDNGMVEDLELKVVTKRAPTAQELEDMKFAFKIAKHVKSNAVIYAKDGQTAGIGAGQMSRVDSARIAAQKAEDAAKALGLAEPLTRGSAVASEAFYPFADGLLAAIAAGATAVIQPGGSMRDQDVIDAANEHNVAMVFTGMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: CMR1_CRYNJ
Sequence: MDEETAYELERQKTIAENRALLDSLGLDPAGASSPFGSSPAPTSNKTKPKPKPAPKKRKAAAVIAVDEGPRRRSGRIAGLEADGDAFKAKVEEEEKEREILRVVSRKEREKVMDVGKMVEDTPEDEIKDMEKYLQSIAELSNPRTYPAGTVSAREAYADSDTVPSEVQRLKDAFKDMSLKGNTKVTNERVFSMCVHPEKTKTLVLVGDKYGQLGIWDALGPPMEKPENEDDTSGLLRAEGEDEYQEGRVWRVQAHAKNSISCMKVDPVNGSGLFSTAYDCSLRHLSFSTLQSTELFSFQDEDLLINHFDLLPSAQEAWMVDKNGGISHWDTRESKRESGRRRWVVQEEGRGAKLGGVSVNPLMPHLICTAGNDQHVRIWDTRHLFSISSNLVPSAAAIEEEEEGTSTLSGQSSSLPHDTHPTRESDYSTVTSYLASPRGKGLMRAKWQHGKSCSSAYWDPWGRRILTTSYDDHLRVFNIDPGSSLVDDRAVGSLLQPNGFKPTKVVRHNCQTGRWLTILRAQWSLNMEYMPHFTVGNMKRTLDVVSATGEKIVGLWTDDVTAVPTVTASHPNIVDRVVGGNTSGRIQLWSSGDHI
What is the function of this protein?
DNA-binding protein that binds to both single- and double-stranded DNA.  Binds preferentially to UV-damaged DNA.  May be involved in DNA-metabolic processes.
What are the official names of this protein?
DNA damage-binding protein CMR1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat DDB2/WDR76 family.
Protein: PKDRE_MOUSE
Sequence: MWPGPALLLLGLGLGLGSQPPPTGPRGLPGVLRGAPGLGQGAESSVRGGDTGGLSPRAAPRHASPTPPRRCPSGAAARVLLKVNSSDPAAAKANVSCQTAPCIMQPVKINRKDQNAPLILSRDEEATLNITVRWYCPDALVIRKSWVYFSVASVNDTPDWNRPVLLPQVAVSKGFSLHIPKYALPYGVYVFNFTLSIFRWDLAWPTVTGSDIIYIWVRKRPLKAVLLGAPRVTVKFSDELILNGSMSYDPEADIPTWGLQFFWYCTTNPRYYSGNYVLVINQAVCHPEQDSLNWPWAVGSVLTIPPKTLRGNGVYYFRMVVQKQNRTAFSDKTVHVLQGLQPKAHISCIENCGPTLGVSDRFSLFLNCPSCGRQDLYSWSILSLTGHEVMFDWAGQAITRRNGPYLSIKAFAFRNFLENRVWVSLILKSWSGMTTTLRHPVVINHGPRVGKCKINPASGISMVTKFAVECSDFKDENLPLKYKIIVSELDSIGAISSVEENTLGSVVYSGAEPITPAFFLPVGTVTDEYNVRLYVQVYDSLGTFSQVTLQATVTAPTVRDSSKDVLQQLLNVTMKPTSLLSTLLQKQDWLQAGYLTYVVISVLNNIKGEQELQDDRARLLEHLVKQSLTFAMNTADEIGQSVMVITKLTQKASDLSQADLEATSFRLRQASQDLQEYQHRHKHLQQVEVVGTGILTSLSNLLKLINPYYTLQDPLFVVESLSDTILANKVPGSKTTALRTSYFNMYVEKVENWNVFKAFRNDSLCPNCLRATLNASTVPRLPAKAPISMMFCEFADDPFPWLTYPENISVDVVGFRMTGVADNNKVIEITPDIAEVYLVRKDLTPSSFNLTVGPGIKSDGFSKVTTGGISFEVDSRWTGELLIHIVTNVTVLFEALVYEGCQLTPTNLMATFLVPNDIPPIVKWSGLFDPTCSVKEARVVCLSSSLLRSIAQRRFSFKYNISMVLQASRFVLKPTNKLVRIALFMVHCLDMYGIQSDWQQSTCVLGEKTTWKTVHCVCRNGRRSRRQLTSVKLTYHHLHTHFVTAKVIVVPNPVDLRLAIISNLTQNPATFLAVLFIMILYAILAFWALHRDVIDLYFRDNVVILTDNDPFDTLCYLVTIFTGSRWGSGTRANVFIQLMGTEGTSDVHCLSHPYFKTLYRGSINTFLLTTKNDLGDIHSIRVWHDNSGEAPSWYLSRIKVENLFNKRIWLFVCRRWLSVDTTLDATFSVTNPDEPLKRTDFFMIDVRDKLRKNHMWISIFTEIVPKPFNRLQRLSCCLAMLLSSLVCNIMFFNLNQKEKIESRHMHIIRSMLIGIESVVITIPVQLLITFFFTYSQKNLKMNLDKVAPQKHPLMSEEGLSWKERLHKWHEYEMKALPRRAAVSTSAPEEKEAFETSQKHEKADTQMSNKNSSNNNQEASEGVPPKAFSSQPHTTESVQKKTQIILPRWCVYIAWFLVFATSGISSFFIVFYGVTYGYAKSIEWLFASFCSFCQSVFLVQPCNILLRSGTRSYKPKYCKNLSWSSKYHYSEIRLQGLTMTQEEMEQLHEDIAYVRSLSMYQPITEDKIQILRRENRIRRRSFLFLSYLVTHFIFLTLLLLLIFSLRHNDSFYYNQFIRHRFSVDLATVMKLGDIYTWLHGVFLPLLHNDPNPTFLPDSSSKILGLPLVRQVRARPSNKTCLLAKKFVQSSVAGEIHCHPQYGIDPEDTQHYSSVWSKAGKQSTDKASHGFTYKPPGKRWVYHSYGVLNTYGSGGYVFYFFPGQQMFNSTVRLKELEGKNWLDELTWAVIVELTTLNPDTSLMCSISVVFEVSPLGVVNSSLSVYSFSLADFNRKTSSEIYLYAAILIFFCAYVVDEGYIIRQERASYIRSVYNLLNFSLKCMFALLIVLFFWKYFLATKMVQLYLADPEAFIPFHAVSRVDHFMRIILAFLLFLTILKTLRYSRFFYNVRLAQKAIQAALPGICHTALVVSIYSFMYVAFGYLVFGQHEWNYSNMIHATQTIFSYCVSAFQNTEFSGNKVLGVLFLSSFMLVMICIFINLFQAVILSAYDEMKQPVYEEPSDEAEAVTYLCNRLKSGFDFLTTRSRDKDQSNFFVDMLYGQPEKNTRRFLGLKARNINGKKMIYLVV
What is the function of this protein?
May have a central role in fertilization.  May generate a Ca(2+) transporting channel directly involved in initiating the acrosome reaction of the sperm.
What are the official names of this protein?
Polycystin family receptor for egg jelly, PKD and REJ homolog, Polycystic kidney disease and receptor for egg jelly-related protein.
What is the protein family that this protein belongs to?
Belongs to the polycystin family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.