PharMolix/UniProtQA huggingface dataset:
Protein: CRCB_RALSO
Sequence: MSGMGFVAVGVGAALGAWLRWAFAVLWNAINPALPYGTLAANLLGGYLIGVAVGFFDTHASLPPEWRLLAVTGFLGGLTTFSTFSSEVMANILAGDYAIGMLHVAAHLGGSLFLTMLGLWTVRTLG
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TIM21_BOVIN
Sequence: MICTLLRAVRCTERLHGCPGKPWFLPHSVPHRACSQTEPRWRWGLQEQNTTARPRCIWGVTQRSIWTQVRSPQSAKEDGSKQVSVHRSQGGETVLSTSQKVKEAGRDFTYLIVVLIGISITGGLFYTIFRELFSSSSPNKIYGKALEKCRSHPEVISVFGEPVKGYGEVTRRGRRQLVSFIEYKKDGLKHMRVKFYIQGSEPGKQGTVHLEVKENPESGEYEFRYIFVELEPYSRTIVVEDNRS
What is the function of this protein?
Participates in the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.  Also required for assembly of mitochondrial respiratory chain complex I and complex IV as component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex.  Probably shuttles between the presequence translocase and respiratory-chain assembly intermediates in a process that promotes incorporation of early nuclear-encoded subunits into these complexes.
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit Tim21, TIM21-like protein, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the TIM21 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: RS6_ALBFT
Sequence: MRHYEIILMIHPDQSEQVPAMLERYKGMITAGGGKVHRVEDWGRRQLVYMINKLAKAHYLCVNIEADQAVMAELEHAFKFNDAVLRHLTVLKKKADTGPSSMMKTVEREDARKTQQAEYQA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: TGT_ALIF1
Sequence: MKYELIKKQGRARRGQLQFDRGTVETPAFMPVGTYGTVKGMTPEEVKGTGAEILLGNTFHLWLRPGQEIMKLHGDLHDFMNWKGPILTDSGGFQVFSLGKTRKITEEGVHFRSPVNGDKIFMDAEKSMQIQYDLGSDVVMIFDECTPYPATHDEARISMERSIRWAERSRNEFDRQENPNALFGIVQGGVYEDLRDVSVEALTKIGFDGYAVGGLAVGEPKEDMHRILEHTCPQLPEDKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGHLFVTGGVIKIRNAKHKTDTTPLDPECDCYTCQNYSKSYLHHLDRCNEILGARLNTIHNLRYYQRIMASIRKALEEDRFEQFVEEFYARRDREVPPLKDL
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: HIS6_CHLTE
Sequence: MLAKRIIPCLDVRDGRVVKGINFEGLRDAGSILEQARFYNNEMADELVFLDISASLESRRTTLEEVLKVSGEVFIPLTVGGGISSVERAHDAFLHGADKVSVNTAAVSEPELISRIAEKFGSQAVVVAIDVKKVDGRYIVHTHSGKKPTEYEAVEWAHKVQELGAGEILLTSMDRDGTQEGYDNEILKMISTTVHIPVIASGGAGNLEHLYRGFTDGHADAALAASIFHFRTYSIRQAKEYLRERGITVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIM22_KLULA
Sequence: MVYRGFGLDQVSPPENKPFDQLSPEEQGEKGAQMMVEFMTSCPGKAAISGVTGFALGGVFGLFMASMAYDTPLHTPAPTNAPGLPNKVKELADLPLKQQIKIQFSDMGKRSYSSAKNFGYIGMIYSGVECVVESLRAKNDIYNGVAAGCLTGGGLAYKSGPQAALVGCAGFAAFSTAIDLYMRNENKKPPKDDFDE
What is the function of this protein?
Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane.  In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel.  Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit TIM22.
What is the protein family that this protein belongs to?
Belongs to the Tim17/Tim22/Tim23 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL34_SALPC
Sequence: MKRTFQPSVLKRNRSHGFRARMATKNGRQVLARRRAKGRARLTVSK
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: RS19_CAMHC
Sequence: MARSLKKGPFVDEYIIKKVIAAKKAKDNKPIKTWSRRSTITPEMIGLTFNVHNGKSFIPVYVTEHHIGYKLGEFAPTRTFKGHRGSVQKKIGK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: YCF36_CYAPA
Sequence: MCTFCPIPTEQQPLNEYQILNNSVLFNWPSQKLKIYFFYLFTIYSIGFLLTFLITFYNDLFIVHPVNIFVHGIIGGNFVLILDLLRLYLGWSYICQRLLSATVSYEESGWYDGQIWVKSSEVLIQDRLIGIYQVRPVLNRLKQTLGVVILILGFTLLIQ
What are the official names of this protein?
Uncharacterized protein ycf36.
What is the protein family that this protein belongs to?
Belongs to the ycf36 family.
What are the subcellular locations of this protein?
Plastid, cyanelle.
Protein: SECB_ACICJ
Sequence: MSETQIAPLTLNIQYTKDLSFEVPGAPAIYTLLRQAPTVNINLDVQVQRLQDDAHVYEVTLTTRAEATHPAPAESGNGAEGGKDLTVFIADLSYAGVFTLTGIPDNQIEPVLLVECPRLLFPFARNILADVTRDGGFPPVMLGPVDFVGLWQARRAQDDGETIANA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGB3_CVB
Sequence: MSLSYLDLLLAFGCVLAVSVIVNCFLVSHNNCVIEITGEAVRISGCTFDRTFVELVKGLKPARH
What is the function of this protein?
Plays a role in viral cell-to-cell propagation, by facilitating genome transport to neighboring plant cells through plasmosdesmata.  May induce the formation of granular vesicles derived from the Endoplasmic reticulum, which align on actin filaments (By similarity).
What are the official names of this protein?
Movement protein TGBp3, 7 kDa protein, Triple gene block 3 protein, TGBp3.
What is the protein family that this protein belongs to?
Belongs to the Tymovirales TGBp3 protein family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane.
Protein: ILVC_TRIV2
Sequence: MARMYYDEDANLDLLAGKTIAIIGYGSQGHAHALNLKDSGLNVIVGLYPGSKSAEKAQAAGLTVKNVADAANVADFIMILLPDEVQKTVYKNEIEPNLQEGNTLAFAHGFNIHFGQVVPPANVDVVMVAPKGPGHLVRRTYEQGQGVPALFAVYQDASGKARDRALSYAKGIGGTRGGVLETTFREETETDLFGEQAVLCGGLSALIKAGFETLVEAGYQPELAYFECLHEVKLIVDLVVEGGLAKMRDSISNTAEYGDYTRGPRIVNEQTKAEMRKVLSEIQSGQFAREFVLENQSGKPGFTAMRRQEAEHPIEEVGKDLRAMFSWLKKV
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: 5HT1D_CANLF
Sequence: MSPPNQSLEGLLQEASNRSLNATETPEAWGPETLQALKISLALLLSIITMATALSNAFVLTTIFLTRKLHTPANYLIGSLAMTDLLVSILVMPISIAYTTTRTWSFGQILCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGRAAVMIATVWVISICISIPPLFWRQAKAQEDMSDCQVNTSQISYTIYSTCGAFYIPSVLLIILYGRIYVAARNRILNPPSLYGKRFTTAQLITGSAGSSLCSLSPSLQEERSHAAGPPLFFNHVQVKLAEGVLERKRISAARERKATKTLGIILGAFIVCWLPFFVASLVLPICRASCWLHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQRVVHVRKAS
What is the function of this protein?
G-protein coupled receptor for 5-hydroxytryptamine (serotonin).  Also functions as a receptor for various alkaloids and psychoactive substances.  Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase.  Signaling inhibits adenylate cyclase activity.  Regulates the release of 5-hydroxytryptamine in the brain, and thereby affects neural activity.  May also play a role in regulating the release of other neurotransmitters.  May play a role in vasoconstriction.
What are the official names of this protein?
5-hydroxytryptamine receptor 1D, 5-HT-1D, 5-HT1D, Serotonin receptor 1D.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PG056_VACCA
Sequence: MLNRIQTLMKTANNYETIEILRNYLRLYIILARNEEGHGILIYDDNIDSVMSMMNITILEVIGLTTHCTKLRSSPPIPMSRLFMDEIDHESYYSPKTSDYPLIDIIRKRSHEQGDIALALERYGIENTDSISEINEWLSSKGLACYRFVKFNDYRKQMYRKFSRCTIVDSMIIGHIGHHYIWIKNLETYTRPEIDVLPFDIKYISRDELWARISSSLDQTHIKTIAVSVYGAITDNGPIPYMISTYPGNTFVNFNSVKNLILNFLDWIKDIMTSTRTIILVGYMSNLFDIPLLTVYWPNNCGWKIYNNTLISSDGARVIWMDAYKFSCGLSLQDYCYHWGSKPESRPFDLIKKSDAKRNSKSLVKESMASLKSLYEAFETQSGALEVLMSPCRMFSFSRIEDMFLTSVINRVSENTGMGMYYPTNDIPSLFIESSICLDYIIVNNQESNKYRIKSVLDIISSKQYPAGRPNYVKNGTKGKLYIALCKVTVPTNDHIPVVYHDDDNTTTFITVLTSVDIETAIRAGYSIVELGALQWDNNIPELKNGLLDSIKMIYDLNAVTTNNLLEQLIENINFNNSSIISLFYTFAISYCRAFIYSIMETIDPVYISQFSYKELYVSSSYKDINESMSQMVKL
What is the function of this protein?
Plays a role in intracellular enveloped virus (IEV) transport to the cell surface through microtubule transport.  Together with protein OPG064, forms a complex that interacts with host KLC2 (kinesin light chain isoform 2) to engage the kinesin-1 complex and thereby promote IEV trafficking.
What are the official names of this protein?
Protein OPG056, Protein F12.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG056 family.
Protein: G1PDH_METMJ
Sequence: MSADRINLLRTKVFDKSKWMQLPRDVVIGHDVIEQIPAVCEDLALGDSVLIVSGGQTRDIAGKRVEALLAGSYDVVTFAANDGNPFETIRKAEEAAATAGFVIGVGGGRVIDTAKIASYNTDRHFISVPTAASHDGIASSRASVPTADGNVSLAAEPPIAVVADTAVIASAPHRLLASGCADIIANYTAILDWELSHRLRGEPLSEYALTLSRMTAEILFKNADLIKPHSEESAWLVTKALVSSGVAMSIAGSSRPGSGGEHKFSHALEKLAPGKGLHGEKCGIGAIITMYLHGGDWEGIRDSLKKIGAPTTPAAIGVDDETAVAALLAARTIRPERFTILDMGLTEESARDLVKMLYRE
What is the function of this protein?
Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P).  The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
What are the official names of this protein?
Glycerol-1-phosphate dehydrogenase [NAD(P)+], G1P dehydrogenase, G1PDH, Enantiomeric glycerophosphate synthase, sn-glycerol-1-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glycerol-1-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNRN_NEIGO
Sequence: MTDFSVWEAAPFGATVDHILQRYHNVHRAQFEELVPLAQKVAQVHADTFPAEIAGLLADMRDELLMHMMKEERMLFPMINQGVGRGAAMPISVMMHEHEEHDRAIARLKELTGNFHAPEGACGSWTRLYALAKEMADDLNDHIHLENDILFARVLDS
What is the function of this protein?
Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions.  Required to repair damage caused by nitric oxide to FNR and NsrR transcription factors.
What are the official names of this protein?
Iron-sulfur cluster repair protein DnrN.
What is the protein family that this protein belongs to?
Belongs to the RIC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPC_CHLPN
Sequence: MFEKFTNRAKQVIKLAKKEAQRLNHNYLGTEHILLGLLKLGQGVAVNVLRNLGIDFDTARQEVERLIGYGPEIQVYGDPALTGRVKKSFESANEEASLLEHNYVGTEHLLLGILHQSDSVALQVLENLHIDPREVRKEILKELETFNLQLPPSSSSSSSSSRSNPSSSKSPLGHSLGSDKNEKLSALKAYGYDLTEMVRESKLDPVIGRSSEVERLILILCRRRKNNPVLIGEAGVGKTAIVEGLAQKIILNEVPDALRKKRLITLDLALMIAGTKYRGQFEERIKAVMDEVRKHGNILLFIDELHTIVGAGAAEGAIDASNILKPALARGEIQCIGATTIDEYRKHIEKDAALERRFQKIVVHPPSVDETIEILRGLKKKYEEHHNVFITEEALKAAATLSDQYVHGRFLPDKAIDLLDEAGARVRVNTMGQPTDLMKLEAEIENTKLAKEQAIGTQEYEKAAGLRDEEKKLRERLQSMKQEWENHKEEHQVPVDEEAVAQVVSLQTGIPSARLTEAESEKLLKLEDTLRRKVIGQNDAVTSICRAIRRSRTGIKDPNRPTGSFLFLGPTGVGKSLLAQQIAIEMFGGEDALIQVDMSEYMEKFAATKMMGSPPGYVGHEEGGHLTEQVRRRPYCVVLFDEIEKAHPDIMDLMLQILEQGRLTDSFGRKVDFRHAIIIMTSNLGADLIRKSGEIGFGLKSHMDYKVIQEKIEHAMKKHLKPEFINRLDESVIFRPLEKESLSEIIHLEINKLDSRLKNYQMALNIPDSVISFLVTKGHSPEMGARPLRRVIEQYLEDPLAELLLKESCRQEARKLRATLVENRVAFEREEEEQEAALPSPHLES
What are the official names of this protein?
Probable ATP-dependent Clp protease ATP-binding subunit.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family. ClpC subfamily.
Protein: CYB_ARTFR
Sequence: MTNIRKTHPLLKIINSSFVDLPAPSSLSSWWNFGPFLGVCLGVQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWLLRYLHANGASMFFICLYLHVGRGLYYGSYTYSETWNIGILLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVQWIWGGFSVDKATLTRFFAFHFLLPFIVTALVMVHLLFLHETGSNNPTGIPSDPDMIPFHPYYTIKDILGFLVMLTALATLVLFSPDLLGDPDNYIPANPLMTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVMSILILAIVPILHMSKQRSMMFRPFSQCLFWLLVAVLFTLTWIGGQPVEHPYIIIGQTASVLYFLIILFLMPMISLVENYLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RECU_STRZT
Sequence: MVNYPHKLSSQKRQPSLSQPKNFANRGMSFEKMINATNDYYLSQGLAVIHKKPTPIQIVRVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEAKETKQKRAIPMKNFHPHQIQHMEQILAQQGICFVLLHFSSQQETYLLPAYDLIRFYHQDKGQKSMPLGYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR
What is the function of this protein?
Endonuclease that resolves Holliday junction intermediates in genetic recombination.  Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands.  Promotes annealing of linear ssDNA with homologous dsDNA.  Required for DNA repair, homologous recombination and chromosome segregation.
What are the official names of this protein?
Holliday junction resolvase RecU, Recombination protein U homolog.
What is the protein family that this protein belongs to?
Belongs to the RecU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCUP_CAMC5
Sequence: MIFVDACLKKPTPYTPVWMMRQAGRYLPEYMAVRERAGDFLSLCKDYKKASAVTIQPVEILGVDAAILFSDILVVPLEMGMGLRFEKGEGPVFDRPVKTAGDLAVLDVDRAVKNLSYVYDTIALTRENLARDKALIGFCGAPWTIATYMIEGGGTKTYAVCKKLLYTNPEFLHQILAKVTAALTDYVKAQIRAGVDAVQIFDSWAGALEESAYFEFGWRYILQIVDSVKTEFPDIPLIVFPKGVSGFLDKISGNFEVFGVDWSTPIGLAKEKLSPKFVLQGNMEPTRLYSKKAIDAGVDKILNTMKGAPHIFNLGHGILPDIPVENAKYFIKQVQEKSHNHK
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCBP1_ORYSJ
Sequence: MSAGWRTLLLRIGDRCPEYGGSADHKEHIETCYGVLCREYEHSKDAMFEFLLQCADQLPHKIPFFGVLIGLINLENEDFSKGIVDTTHANLQDALHNENRDRIRILLRFLCGLMCSKVVLPNSIIETFEALLSSAATILDEETGNPSWQPRADFYVYCILASLPWGGSELFEQVPDEFERVLVGIQSYISIRRHFDDIAFSVFETDEGNSPNKKDFIEDLWERIQVLSRNGWKVKSVPKPHLSFEAQLVAGVSHRFSPISCPPPTISQSSSEIVKGQEKHEADLKYPQRLRRLHIFPTNKAENMQPVDRFVVEECILDVLLFFNGCRKECAFYLVSLPVPFRYEYLMAETIFSQLLLLPNPPFRPIYYTLVIIDLCKALPGAFPSVVVGAVHALFDRISNMDMECRTRLILWFSHHLSNFQFIWPWQEWAYVKDLPKWAPQRVFVQEVLEREIRLSYFDKIKQSIEDAVELEELLPPKAGPNFRYHSDEGKESTDGHRLSKELVAMVRGRKTQGDIISWVDEKIIPVNGAKFALDVVSQTLLDIGSKSFTHLITVLERYGQIISKLCPNEEMQLLLMDEVSAYWKNSTQMIAIAIDRMMGYRLLSNLAIVKWVFSPANVDQFHVSDRPWEILRNAVSKTYNRIFDLRKEIQTLRKGLQAAKEASEKAARELEEAKSIIEIVDGQPVPSENPGRLRRLQARADKAKEGEVTTEESLEAKEALLARGLEESKELLRLLFKSFVEVLTERLPPISADGDVPNLRAGDPNVNSSARDPEATTMEIDNENGGDNDSQLNGQNKKISHNVGELEQWCLCTLGYLKSFSRQYATEIWSHIAMLDQEIFVGNIHPLIRKAAFSGLCRPTSEGSHL
What is the function of this protein?
Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs).  The CBC complex is involved in miRNA-mediated RNA interference and is required for primary miRNA processing.  In the CBC complex, ABH1/CBP80 does not bind directly capped RNAs (m7GpppG-capped RNA) but is required to stabilize the movement of the N-terminal loop of CBP20 and lock the CBC into a high affinity cap-binding state with the cap structure (By similarity).
What are the official names of this protein?
Nuclear cap-binding protein subunit 1, 80 kDa nuclear cap-binding protein, CBP80, NCBP 80 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the NCBP1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Predominantly nuclear.
Protein: RS16_SYMTH
Sequence: MALKIRLKRMGMKKTPFYRLVVTEATSPRDGRFVEEIGYYDPTKNPVVLNIDEEKALNWLLKGATPTETTRALLSKAGVLKKFDEARK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: NUSB_BACAA
Sequence: MKRRTARERAMQALYQMDITGELEPKVAVENTLDEGEETNEFLESLVVGFVENKEVIDEAIRQNLKKWKLERISIVDRSILRVAVYEMKYMEEIPHNVTINEAIEIAKTFGDEESRRFINGVLSNIKDTL
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: RL33_ALIB4
Sequence: MANAVRIKIGLKCQESGDINYTTWKNPKTHTEKFEVKKYCPRLKKHTTHKEVKLKS
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: ATPB_CARHZ
Sequence: MNVGRVVQVIGVVVDVEFEPGKVPPIYNALKIRSEDQDTPTEVPINLTLEVAQHLGNNRVRAVAMSSTDGLVRGMKVVDTGAPITVPVGRPVLGRLLNVLGEPIDGKGPVESDHYYPIHRPAPPLEEQSTRAEILETGIKVIDLLVPFLKGGKIGLFGGAGVGKTVIVMELINNIAKQHGGISVFAGVGERTREGNDLYHEMKEAGVLDKTIMVFGQMNEPPGVRLRVGLTGLTMAEYFRDEEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTRKGSITSVQAVYVPADDLTDPAPATTFAHLDATVVLSRQIAELGIYPAVDPLDSTSRILDPHIVGEEHYQVARGVQRVLQRYKELQDIIAILGMDELSDEDKLIVARARKLQRFLSQPFTVAEAFTGRPGKYVPVKETIRGFKEILEGKHDDIPETCFYMAGTIDEVVERARELEGSA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SDHL_HELPY
Sequence: MASFSILSIFKIGVGPSSSHTIGPMEAGARFCESLKGILEQVVRVQITLHGSLALTGKGHLSDEAVLIGLHGIYANELEVTTKKALLHEALENKVLKLANQHHIPFDYAKDLIFDNKPLTRHQNALILKAFNSKNEVLKEETYYSVGGGFVYTEKELDNLSEEDGNESIAYDFSSAKELLELCQKHQKSIAEIVRLRENALKNHPDATMVKIYHAMLECYDNGANSKERYLPGSLKVTRLAPSIKTRLEKHPTSGKDPLALIDYISLYARAIAEENASGGKVVTAPTNGACAVVPSVLLYAKNHLFENLSQKAINDFLLTSAAIGYLYKKNASLSGAEAGCQAEIGVASSMAAGGLAHLCQATTQQVLIASEIAMEHHLGLTCDPVGGLVQIPCIERNVLGAIKAISASKLALEDEYKPKVSLDEVIATMYATGKDMNEKYKETSLGGLAKTLKC
What are the official names of this protein?
L-serine dehydratase, SDH, L-serine deaminase, L-SD.
What is the protein family that this protein belongs to?
Belongs to the iron-sulfur dependent L-serine dehydratase family.
Protein: RFCL_HALMA
Sequence: MDWTEKYRPTTLSEVRGNDKARDALKKWAETWDDHREAVILYGSPGIGKTSAAHALANDMEWPTIELNASDSRTKDVINRVAGEAAKSGTLTAGGGGRRLVIMDEADNIHGNADRGGARAITALVKEASQPMILIANEYYEMSNGLRNNCQDIEFRDVSPRSIVPVLRDLCRQEGVEYESDALQELAEQNSGGLRGAVKDLQAIAETTERLTADDVVTGERDTTEGIFEYLDVVLKEAGAQDALEASYDVDETPDDLINWIEDNMPKDYEGTELVRAYEFLSNADQWLGRVRETQNYSFWRYAGDNMTAGVAAARDGTKGGWTRYGPPSYWSKLGRSKGTRNTRDYVAQQIAAIDGVSMRTARREIMPFLATMTHHCRNRELTVAMAATYDMEAEHVSFVTGSGKDTNKVQDIVADAEALKEEAAVEHSGGVFEGASANGGDGDSDADGDAPDTDAGEESGDQQVTLAADDGAESDATSDGTTTDDETETASEAAEDDDQQSGLSDFM
What is the function of this protein?
Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.
What are the official names of this protein?
Replication factor C large subunit, RFC large subunit, Clamp loader large subunit.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family. RfcL subfamily.
Protein: HMOX2_RAT
Sequence: MSSEVETSEGVDESENNSTAPEKENHTKMADLSELLKEGTKEAHDRAENTQFVKDFLKGNIKKELFKLATTALYFTYSALEEEMDRNKDHPAFAPLYFPTELHRKEALIKDMEYFFGENWEEQVKCSEAAQKYVDRIHYVGQNEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPSTGEGTQFYLFEHVDNAQQFKQFYRARMNALDLSMKTKERIVEEANKAFEYNMQIFSELDQAGSMLTKETLEDGLPVHDGKGDVRKCPFYAAQPDKGTLGGSNCPFRTAMAVLRKPSLQLILAASVALVAGLLAWYYM
What is the function of this protein?
Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron.
What are the official names of this protein?
Heme oxygenase 2, HO-2.
What is the protein family that this protein belongs to?
Belongs to the heme oxygenase family.
What are the subcellular locations of this protein?
Microsome membrane; Single-pass type IV membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Single- pass type IV membrane protein; Cytoplasmic side.