PharMolix/UniProtQA huggingface dataset:
Protein: END4_MYCPN
Sequence: MPKLLGSFISFKSPHYLVGSVRDAVSIKAQAFMIFLGAPHTALRVDPNRMQIDEGHTLMEQHNLSKSGMVVHAPYIINCASKDPVKQTFAIDVLTREVKLCHAVGAKLIVLHPGSAVEQTQTQALDHLIKVLNTVIANTKEVIICLETMAGKGNEIGRDLDQLKYVINHIEQQERIGVCLDTCHFHDSGNDFNNTAEIMETIDTKLGFEFLKVIHLNESKNVCGSKKDRHANLGEGMIGFDNLMRFIAQPQIKQIPIVLETPSDKHNYPAVYGAEIERIRAWFGAR
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: BGL19_ORYSJ
Sequence: MCGCASGEDAMETRRPLHPLLLFFSPWLLLLLLLVVQGVRSLQFTRDDFPDGFTFGAGTAAFQYEGAAAEDGRTPSIWDTYAHSWRNPGGETGDVACDGYHKYKEDVMLMNETGLEAYRFTISWSRLIPSGRGAVNPKGLQFYNSMINELVKAGIQIHAVLYHIDLPQSLQDEYGGWVSPKVVDDFAAYADVCFREFGDRVAHWTTSIEPNVMAQSGYDDGYLPPNRCSYPFGRSNCTLGNSTVEPYLFIHHTLLAHASAVRLYREKHQAAQKGVVGMNIYSMWFYPLTESTEDIAATERVKDFMYGWILHPLVFGDYPETMKKAAGSRLPLFSDYESELVTNAFDFIGLNHYTSNYVSDNSNAVKAPLQDVTDDISSLFWASKNSTPTREFLPGTSLDPRGLELALEYLQEKYGNLLFYIQENGSGSNATLDDVGRIDCLTQYIAATLRSIRNGANVKGYCVWSFMDQYEMFGDYKAHFGIVAVDFGSEELTRQPRRSARWYSDFLKNNAVIKVDDGSVSTAFHAQL
What are the official names of this protein?
Beta-glucosidase 19, Os5bglu19.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
Protein: PNP_CHLPB
Sequence: MFIRKEIDLGDGKVITIETGKMAKQADGATIVRMGDTMVIATVVSSRTPPSPNQDFFPMQVEYREKYYAAGKFPGGFIKRESRPSEKEILSARLIDRALRPLFPNGYYQDTQIIISVISSDQLNDADVLGGIAASAAIMVSDIPFANSMSEVRVGRINGEFVINPTINELAQSDIDISIGGTNDTICMLEGEMNEISEAEMLEAIRFGHEAIKKICSLQDDIAAEVNKPKRSFLAIDAPDELKESIKEACEAPLKELAYMPLAKEERAEKTTAVYKSITEQILGRYKNEITAEDIAADPSKALYLNEQIISGHIHAIEKQVMRHMILDDAKRLDGRKLEEVRPISIELGLIPRAHGSALFTRGETQALVVLTLGTKKDAQMIDTLLDDTEKRFMLHYNFPPFSVGETGRVGGVGRREIGHGNLAERAVKKVVPSESEFPYTIRLVSEILESNGSSSMASVCGATLAAMDGGVPLTKPVSGIAMGLIKEDDNYAVLSDILGNEDHLGDMDFKVAGTRDGITACQMDIKIDGLDYHILEKALEQSKNGRLHILDKMTESIADPRGEIGQYAPKLSTIQVPVDAIGMIIGKGGETIRSITEETGAQINVDDDGTVTISSPNGESAAAAIETIKTLISKPEVGTIYMGKVKDIREDLGAFVEILPRTDGLVHISEIARERVNKVSDHLKQGDRVKVKLIDIRKDQRSGKIRYALSIKALLDMPAESANGPSAQEEQNQ
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DN7A_SULID
Sequence: MTTVKFKYKGEEKQVDISKIKKVWRVGKMISFTYDEGGGKTGRGAVSEKDAPKELLQMLEKQKK
What is the function of this protein?
Can constrain negative DNA supercoils.  May be involved in maintaining the integrity of the genome at high temperature.
What are the official names of this protein?
DNA-binding protein 7a, 7 kDa DNA-binding protein a, Sis7a.
What is the protein family that this protein belongs to?
Belongs to the 7 kDa DNA-binding/endoribonuclease P2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS82_DECAR
Sequence: MSRFWSQVVRDLTPYVPGEQPKIANLIKLNTNENPFPPSPRVVAAIQAELGDDAARLRLYPDPNADLLKAAVARRHTVSAQQVFVGNGSDEVLAHIFMALLKHDQPIIFPDITYSFYPVYCGLYGVEYQTLPLADDFSINPADYCDRPNGGIIFPNPNAPTGRLLPLDAIEQMLKANPDSVVVVDEAYVDFGGETAISLVDRYDNLLVVHTLSKSRSLAGMRVGFAVGHAALIEALERVKNSFNSYPLDRLAIVAAVAAMEDEAYFAQCCHAVMATRNTLTAELTELGFEVLPSTANFIFTRHPQRDAAELAKALRERNIIVRHFKLPRIDQFLRITVGTDGECKALTDALRQITG
What are the official names of this protein?
Histidinol-phosphate aminotransferase 2, Imidazole acetol-phosphate transaminase 2.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: PYRH_MYCBP
Sequence: MTEPDVAGAPASKPEPASTGAASAAQLSGYSRVLLKLGGEMFGGGQVGLDPDVVAQVARQIADVVRGGVQIAVVIGGGNFFRGAQLQQLGMERTRSDYMGMLGTVMNSLALQDFLEKEGIVTRVQTAITMGQVAEPYLPLRAVRHLEKGRVVIFGAGMGLPYFSTDTTAAQRALEIGADVVLMAKAVDGVFAEDPRVNPEAELLTAVSHREVLDRGLRVADATAFSLCMDNGMPILVFNLLTDGNIARAVRGEKIGTLVTT
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDUU_SALTY
Sequence: MERQPTTDRMIQEYVPGKQVTLAHLIANPGKDLFKKLGLQDAVSAIGILTITPSEASIIACDIATKSGAVEIGFLDRFTGAVVLTGDVSAVEYALKQVTRTLGEMMQFTTCSITRT
What is the function of this protein?
The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low.
What are the official names of this protein?
Bacterial microcompartment shell protein PduU, Bacterial microcompartment protein homohexamer, BMC-H, Propanediol utilization protein PduU.
What is the protein family that this protein belongs to?
Belongs to the EutS/PduU family.
What are the subcellular locations of this protein?
Bacterial microcompartment. Note=The N- and C-terminii are on the convex side of the hexamer, probably inside the BMC (PubMed:18786396) (Probable). Modeling suggests the beta-barrel is on the exterior of the BMC where it interacts with PduV (Probable).
Protein: MARCO_HUMAN
Sequence: MRNKKILKEDELLSETQQAAFHQIAMEPFEINVPKPKRRNGVNFSLAVVVIYLILLTAGAGLLVVQVLNLQARLRVLEMYFLNDTLAAEDSPSFSLLQSAHPGEHLAQGASRLQVLQAQLTWVRVSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAGLQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPGPAGVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERGENSVSVRIVGSSNRGRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKGRALYKVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECSV
What is the function of this protein?
Pattern recognition receptor (PRR) which binds Gram-positive and Gram-negative bacteria (PubMed:9468508).  Also plays a role in binding of unopsonized particles by alveolar macrophages (By similarity).  Binds to the secretoglobin SCGB3A2 (PubMed:12847263).
What are the official names of this protein?
Macrophage receptor MARCO, Macrophage receptor with collagenous structure, Scavenger receptor class A member 2.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: EGG2_SCHJA
Sequence: MKSSLTLLFLAAIGYTIAYPPSSDYDSGYGGGGGGGGGGGYGGWCGGSDCYGGGNGGGGGGGGGNGGEYGGGYGDVYGGSYGGGEYGDVYGGGCGGPDCYGGGNGGGNGGGGGCNGGGCGGVPDFYGKGLLDSYGGDSYGNDYYGGSNGRRNGHGKGGKGGNGGGGGKGGGKGGGNGEGNGKGGGGKNGGGKGGNGGKGGSYAPSYY
What are the official names of this protein?
Eggshell protein 2A.
Protein: KAIB_CYAP4
Sequence: MSPLKKTYVLKLYVAGNTPNSVRALKTLNNILEQEFQGVYALKVIDVLKNPQLAEEDKILATPTLAKILPPPVRKIIGDLSDREKVLIGLDLLYEEFAEAEAEAE
What is the function of this protein?
A metamorphic protein which reversibly switches between an inactive tetrameric fold and a rare, thioredoxin-like monomeric fold (KaiB(fs)).  KaiB(fs) binds phospho-KaiC, KaiA and CikA.  KaiA and CikA compete for binding to KaiB(fs), and KaiB(fs) and SasA compete for binding to KaiC, thus the clock oscillator and output signal pathway are tightly coupled.
What are the official names of this protein?
Circadian clock oscillator protein KaiB.
What is the protein family that this protein belongs to?
Belongs to the KaiB family.
Protein: ARC_MYCA1
Sequence: MGSSERSEAFGTPRESDMSSGDEAELEELRREAAMLREQLEHAVGSHGGARSARDVHQLEARIDSLAARNSKLMETLKEARQQLLALREEVDRLGQPPSGYGVLLATHEDDTVDVFTSGRKMRLTCSPNIDVSLLRKGQTVRLNEALTVVEAGTFESVGEISTLRELLADGHRALVVGHADEERIVWLAEPLVADNLPDGHPDALNDDTRPRKLRPGDSLLVDTKAGYAFERIPKAEVEDLVLEEVPDVSYEDIGGLTRQIEQIRDAVELPFLHKELYREYALRPPKGVLLYGPPGCGKTLIAKAVANSLAKKMAEVRGDDAREAKSYFLNIKGPELLNKFVGETERHIRLIFQRAREKASEGTPVIVFFDEMDSIFRTRGTGVSSDVETTVVPQLLSEIDGVEGLENVIVIGASNREDMIDPAILRPGRLDVKIKIERPDAEAAQDIFSKYLTEELPLHADDLAEFGGDRTACIKAMIEKVVERMYAEIDDNRFLEVTYANGDKEVMYFKDFNSGAMIQNVVDRAKKNAIKSVLETGQPGLRIQHLLDSIVDEFAENEDLPNTTNPDDWARISGKKGERIVYIRTLVTGKSSSASRAIDTESNLGQYL
What is the function of this protein?
ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle.  May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis.  Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
What are the official names of this protein?
Proteasome-associated ATPase, AAA ATPase forming ring-shaped complexes, ARC, Mycobacterial proteasome ATPase.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
Protein: SYD_SHEB5
Sequence: MRSHYCGDVNKSHVGQEVTLVGWVNRSRDLGGVVFLDLRDREGLIQVVYDPDLPEVFNVASTLRAEFCVQVKGLVRARPDSQVNGQMKTGEIEVLGQALTIINAADPLPLSMDNYQNNSEEQRLKYRYLDLRRPEMAQRLIFRAKVTSSVRRFLDSNGFLDIETPILTKATPEGARDYLVPSRTYKGQFFALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDIETSFMSSEQVMAKTEEMMRGLFLEMLNVDLGEFPRMTYNEAMRRFGSDKPDLRNPLELVDIADLLKEVEFAVFSGPANDEEGRVAALRIPGGAALSRKQIDDYTKFVGIYGAKGLAWMKINDLSLGLEGIQSPVLKFLNDSIVNEIVSRTGAQTGDIILFGADQATVVAESMGALRLKAGEDFSLLQGEWRPLWVVDFPMFEKINGNFHAVHHPFTAPRGVTAAELEANPANRVSDAYDMVLNGCELGGGSVRIHNQEMQSAVFRILGITDEEAKEKFGFLLEALRYGTPPHAGLAFGLDRIIMLMTGASSIRDVMAFPKTTTAACPLTNAPGFANPQQLAELGIAVVEKAVKTED
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_BAUCH
Sequence: MSRFCQVTGKRSVSGNNRSYAMNATKRRFLPNLHFHRFWIEAEKRFIKIRVSAKGMRVIDKKGIENCLANLCIRY
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: RAB1A_MOUSE
Sequence: MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTPVKQSGGGCC
What is the function of this protein?
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes (PubMed:20639577, PubMed:22854043).  Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (PubMed:20639577, PubMed:22854043).  RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secretion (By similarity).  Required to modulate the compacted morphology of the Golgi.  Regulates the level of CASR present at the cell membrane (By similarity).  Plays a role in cell adhesion and cell migration, via its role in protein trafficking (PubMed:20639577).  Plays a role in autophagosome assembly and cellular defense reactions against pathogenic bacteria (By similarity).  Plays a role in microtubule-dependent protein transport by early endosomes and in anterograde melanosome transport (PubMed:22854043).
What are the official names of this protein?
Ras-related protein Rab-1A, YPT1-related protein.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Golgi apparatus. Endoplasmic reticulum. Early endosome. Cytoplasm, cytosol. Membrane. Melanosome. Note=Alternates between membrane- associated and cytosolic forms.
Protein: RLMH_METLZ
Sequence: MQIQIVCVGKIKDAYISSGVVEFEKRLRPYGKIFITELAEVKIPDNASASDELRVKEREGELILANVKEGFFKIALDPNGMSLSSEEFSDVFRDAKLSGKNLCFIIGGPLGLSPKLLQSVEKKLSLSRMTFTHPMTRLILLEQVYRAFRILNGEPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Putative ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CMPK2_MOUSE
Sequence: MALISRPRAPLWLGRLSRRLCGRHQACMGTMARPRRFTVELPDCSLTHFVLGDATDHRDARLAELLGPPGRSYALCVPLAPGEGCGPRVQAARVHHRLLQQLRRGPLQRCQLSKLLGYGPGDQAGEAQHGFLLRDPCDHPDTRRDLLQLLGSCQEAARPQLAEFQADSQGLLWQRLWELQGDRQVQVDCACVLPAQEPHLHPLLPDLLNSAVFQDRDAARAVLEECTSFIPEARAVLDLVDQCPKEVQKGKFQVIAIEGLDATGKTTLTQSVSESLKAVLLQSPPPCISQWRKIFDDEPTIIRRAFYSLGNYLVASEIAKESTNFPVIVDRYWHSTATYAIATEVSGGLQYLPPAHHPVYQWPGDLLKPDLVLLLTVNSEERVRRLQGRGQEKTKEEAELEANNVFRQKVEMTYQRMENPSCHLVDASPSRETVLQKVLELIQSSGR
What is the function of this protein?
May participate in dUTP and dCTP synthesis in mitochondria.  Is able to phosphorylate dUMP, dCMP, CMP, UMP and monophosphates of the pyrimidine nucleoside analogs ddC, dFdC, araC, BVDU and FdUrd with ATP as phosphate donor.  Also displays broad nucleoside diphosphate kinase activity (By similarity).
What are the official names of this protein?
UMP-CMP kinase 2, mitochondrial, Nucleoside-diphosphate kinase, Thymidylate kinase LPS-inducible member, TYKi.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SEPF_SYNJB
Sequence: MEGQDDYQLLYEGRRSQPAAPPEEEEVSTLPRGRRQRGVEAGEGSAGREESRGHRRSQHRDRSAGGSMGSNVIGLPGVNPPTSEVVVMEPRSFDEMAQVIQYLRERKTVIMNLTLMDPAEAQRSVDFVAGGTYAIDGHQERIGENIFLFTPSTVMVSTPSSQVVQPLQRPLQSPTPLWPSTYEHLQAVGQH
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: Y012_OSHVF
Sequence: MSLYSKAVNAIVKAVQGNGEELRGIIPNSLCEEIKEEYERRKYTTFIKALDKDGYSSNTDEKIKSLISALEEIEYEIPDDISNVSEIAGEIMYIIEEKDVEFELLSDLIEARGDFSHCRYIRKTCIRYASQSSFCDRMCREYDEDSDDEDDFYDGWPDDGRCFNEDKYDLMDKLEGKYHGVYDLFMLVNELHSDW
What are the official names of this protein?
Uncharacterized protein ORF12.
Protein: SYE2_HELPG
Sequence: MLRFAPSPTGDMHIGNLRAAIFNYIVAKQQHKPFLIRIEDTDKERNIEGKDQEILEILKLMGISWDKLVYQSHNIDYHREMAEKLLKENKAFYCYASAEFLEREKEKAKNEKRPFRYLDEWATLEKDKNHAPVVRLKAPNHAVSFNDAIKKEVEFEPDELDSFVLLRQDKSPTYNFACACDDLLYEISLIIRGEDHVSNTPKQILIQEALGSNDPIVYAHLPIILDEVSGKKMSKRDEASSVKWLLNQGFLPVAIANYLITIGNKVPKEVFSLDEAIEWFSLENLSNSPAHFNLKYLKHLNHEHLKLLDDEKLLKLTSIKDKNLLGLLRLFIEECGTLLELKEKISLFLEPKDIVKTYENEDFKERCLVLFNALKSMDFQAYKDFESFKKEAMRLSQLKGKDFFKPLRILLTGNSHGVELPLIFPYIQSHYQEILRLKA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 2, Glutamyl-tRNA synthetase 2, GluRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_SHIF8
Sequence: MTKKLHIKTWGCQMNEYDSSKMADLLDATHGYQLTDVAEEADVLLLNTCSIREKAQEKVFHQLGRWKLLKEKNPDLIIGVGGCVASQEGEHIRQRAHYVDIIFGPQTLHRLPEMINSVRGDRSPVVDISFPEIEKFDRLPEPRAEGPTAFVSIMEGCNKYCTYCVVPYTRGEEVSRPSDDILFEIAQLAAQGVREVNLLGQNVNAWRGENYDGTTGSFADLLRLVAAIDGIDRIRFTTSHPIEFTDDIIEVYRDTPELVSFLHLPVQSGSDRILNLMGRTHTALEYKAIIRKLRAARPDIQISSDFIVGFPGETTEDFEKTMKLIADVNFDMSYSFIFSARPGTPAADMVDDVPEEEKKQRLYILQERINQQAMAWSRRMLGTTQRILVEGTSRKSIMELSGRTENNRVVNFEGTPDMIGKFVDVEITDVYPNSLRGKVVRTEDEMGLRMAETPESVIARTRKENDLGVGYYQP
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SK1_THEPT
Sequence: EQFDDYGHMRF
What is the function of this protein?
Myotropic peptide.
What are the official names of this protein?
Sulfakinin-1, ThePe-SK-1.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ORF6_SPV1R
Sequence: MDMKFWTTKEYKKIKRDFIIRNFAFGFCYFLFLISFIMCIVCFIISINFEVEIILVILFPFLLLILSVWNLFDLIMEHISEIKRFKVTVLKKQIEELEGKMLRGLRVGVDKIE
What are the official names of this protein?
Uncharacterized protein ORF6, Gene 6 protein.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: RECR_PSEFS
Sequence: MSFSPLIRQLIDALRTLPGVGQKTAQRMALQLLERDRSGGTRLAQALSQAMTGVGHCRQCRTLTEEELCPQCADPRRDDTLLCVVEGPMDVYAVEQTGYRGRYFVLKGHLSPLDGLGPEAIGIPQLVARIEEQGTFTEVILATNPTVEGEATAHYIAQLLTNKGLITSRIAHGVPLGGELELVDGGTLAHSFAGRKPIAL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: PA2_CHEFU
Sequence: TMWGTKWCGSGNKAINYTDLGYFSNLDSCCRTHDHCDNIAAGETKYGLTNEGKYTMMNCKCEATFQQCLRDVHGPLEGKAAFTIRKLYFGLYGNGCFNVQCPS
What is the function of this protein?
Phospholipase toxin, which catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.  Inhibits both skeletal (RYR1) and cardiac (RYR2) ryanodine receptors (calcium release channels).  Probably blocks ryanodine receptors by generating a lipid product (By similarity).
What are the official names of this protein?
Phospholipase A2 large subunit, HfPLA2.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group III subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: COAE_BIFLO
Sequence: MGTMMRIGLTGGIAAGKSTVAARLKQLGALHIDYDALAHQIVEPGGVALPQIVAEFGPDALLADGTMNRPWIADHVFGANAAPGARERLDAIEHPLIYAEAARLEHEHPEAAIIIHDIPLLAEVIDDIPFAFDHIVTVEAPVCMRLDRMVEERGMSLEQAEARIRHQSSEEERRAIADIVIDSTHPLPEMLAQVGEIYAGWCAGR
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SIL1_CANGA
Sequence: MVAKVWSRVILIFIATVMVFASSQQGDANKVNTASPPGANGIAYASVVAGGSNHVSAAGSVTGDGVQLPNAEVDIDWLEEHLEDSHDYEKGYDLVEQHFNKLLVGNNADASFKVRELASRLILGTLRNNPPVKRLIWDQHPLFVSQVFDLYIGNALKQGSGNPLKYPLLKRYLSILLELIPFNRDFRFEEDYKDILDKLYTESDVPSDIKIKVLELITLDYSNIKGASGWIDRITNVLTDSEMGLDELHKRTFFNAMHALKSEDPKLKLPTNFLNWLAQETKERAHNLKLAQAQADDNDLKVRDLEQEEFDQRLVDSRHSVFGNPMAARMKDPYIVDEL
What is the function of this protein?
Required for protein translocation and folding in the endoplasmic reticulum (ER).  Functions as a nucleotide exchange factor for the ER lumenal chaperone KAR2 (By similarity).
What are the official names of this protein?
Nucleotide exchange factor SIL1.
What is the protein family that this protein belongs to?
Belongs to the SIL1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: AROC_MOOTA
Sequence: MLRYLTAGESHGRGLSVIVEGLPAGVPLTDGDINTWLTRRQGGYGRGGRMAIERDQAEILAGVRGGLTLGSPIALFIANRDWENWQEIMAPGPEARAARVVTRPRPGHADLAGGLKYHQADLRNILERASARETAARVAAGAVAAVLLKELAIELAFHVVRIGPVEVREQVDWEAACRAVESPVYCADPEAGRAMVAAIEEARQQGDTLGGVVEVLARGVPAGLGSHVHWDRRLDGRLAQALMSIPAIKGVEIGAGFRVAALPGSRAHDAIAYRKGQGFYHPTNRAGGLEGGLTNGETLVLRAAMKPIPTLMHPLPSVDLVTKQPATASIERSDVCAVPAAAVVAAAAVAWVLAGAILEQFGGDYLPVIQERLAAYRQYLQEI
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: ZN256_HUMAN
Sequence: MAAAELTAPAQGIVTFEDVAVYFSWKEWGLLDEAQKCLYHDVMLENLTLTTSLGGSGAGDEEAPYQQSTSPQRVSQVRIPKALPSPQKTNPCEICGPVLRQILHLVEHQGTHHGQKLYTDGACRKQLQFTAYLHQHQKQHVGQKHFRSNGGRDMFLSSCTFEVSGKPFTCKEVGKDFLVRSRFLQQQAAHTRKKSNRTKSAVAFHSVKNHYNWGECVKAFSYKHVRVQHQGDLIRERSYMCSECGKSFSTSCSLSDHLRVHTSEKPYTCGECGKSYRQSSSLITHRRIHTGVRPHQCDECGKLFNRKYDLLIHQRVHTGERPYKCSECGKSFSHSSSLITHQRIHTGMRPYECSECGKSFIHSSSLITHQRVHTGTRPYMCSECGKSFSQSCHLIKHRRLHIGEGPYECSECGKLFTYRSRFFQHQRVHTGVRSHECHECGKLFSRKFDLIVHERVHTGERPYECSECGKSFTCKSYLISHWKVHTGARPYECGECGKSFTHSSTLLQHQRVHTGERPYECNECGKFFSQSSSLIRHRRSHTGERPYECSECWKSFSNHSSLVKHRRVHTGERPYECSECGKSFSQSSNLTNHQRIHSGERPYECSDCGKFFTFNSNLLKHQNVHKG
What is the function of this protein?
Transcriptional repressor that plays a role in cell proliferation.  Requires TRIM28 for its activity.
What are the official names of this protein?
Zinc finger protein 256, Bone marrow zinc finger 3, BMZF-3.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RLMC_SHESA
Sequence: MSTLVQCGYFERGQCQSCRHIKLPMAQQLAAKNLELQQLLAPFVDKTEPQFLPPVVGDSSGFRNKAKMVALGAAHAPVLGIVSPSGEAVSLCDCLLYPTDMQALLHRLERFVQQAGIPPYRVDKAKGELKFILLTRSQVRGEYMLRFVLRSRDAIARIERELPTLMAEYPQIKVVSVNLQPVHMAILEGEEEIFLTENTRLEERFNDVPLFIRPKSFFQTNPQVAAKLYQTAREWVADFAPASLWDLFCGVGGFGLHCAAKDIPLTGIEIEAEAIACAKMSAQLMGLDKVEFMALDSTDFAKGEAAQTKPELIIVNPPRRGIGESLCHSLSEFAPKAILYSSCNPKTLAKDLGHIRGYRLTKVQLFDLFPHSDHFEVLALLVKD
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC, 23S rRNA(m5U747)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.