PharMolix/UniProtQA huggingface dataset:
Protein: IDI2_META3
Sequence: MSNDIEFRKLEHLFVCNYCDVEYKKGTLLEDVELIHSGISNCDLEDIDTSINLFGKNLGAPIIVAAITGGHSKAKEINKNIAIAIDELNLGMGVGSQRAALINEELMETYSVVRDYTSSLVLGNLGAVNFIEDGWDEETIHKAVEMIDADGMAIHFNPLQEAIQPEGDYNFKGIEILKDIMENYNKTYNNKSNKKIPFIAKQVGEGFSKEDALLLNGLGFDSIDVGGSGGTSWAAVEYYRIKDEESKKFSKKYLEWGIPTAASILEVKQNFDKPIIATGGIRSGMDIAKSMAIGAQCCGVALPVLKAALRGSEDVIKLIENYIEELKTTMFLMGCDNVNELMNSRYIIKNELKEWI
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_BIFLO
Sequence: MVDVANIHLPVLLDDCVNLMAPALEHENAIAVDCTLGLAGHSIAFLKAAPQARLIGIDRDSEALGLATERMEREGLADRFIPVHAAFDQLDQVLADQDIERVDAVFMDLGLSSLQIDETDRGFSYSHDAPLDMRMDVSQPLTAERILATYDAAELVRIFKEYGEERFSRQIARAIVARRDKEPFTTTAQLNRLVDEVVPQAHRPAGNPAKRVFQALRIEVNGELDKLASTLPQAANRLHVGGRLVVESYHSLEDKTVKSFMAQGLRVDVPAGLPVIPPDAQPFFTDLTRGAIKADEHEIAANPRSASVRLRAVEVSREIPSRWRKRFTQTAQGLNDVKIQGSASPGRAKNTARIRTRRG
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA_SYNY3
Sequence: MVNATPFITTKSEEIFAAAQHLMPGGVSSPVRAFKSVGGQPIVFDRVEGAQIWDVDGNQYIDYVGTWGPAICGHAHPDVISALKQALDKGTSFGAPCAQENVLAEMVIDAVPSIEMVRFVNSGTEACMSVLRLMRAFTGREKIIKFEGCYHGHADMFLVKAGSGVATLGLPDSPGVPSNTTKATLTAPYNDLEAVKALFVENPDSIAGVILEPVVGNAGFILPDAGFLEGLRELTKEYGALLVFDEVMTGFRVSYGGAQARFGITPDLTTLGKVIGGGLPVGAYGGREEIMAMVAPAGPMYQAGTLSGNPLAMTAGIKTLEILQKPGSYEYLDKITKRLVDGLLAAAQDAGHEVCGGSISAMFGIFFAPGPVRNYEDAKLADTNKFARFHRGMLERGIYLAPSQYEAGFPSLAHTQEQIDQTIAVAKEVFATL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYAY_YERPP
Sequence: MNDSEFHQLADQLMLYIEETLDSFTGDSDIDYETNGGVMTLTFENGSKIVINRQEPLHQVWLATKAGGYHFNYRDGHWYCSRSGEEFLAKLSEAASAQAGENVSFG
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: MP_MSVPA
Sequence: MDPQSAVYSLPRVPTAAPPNAGVPWSHVGEVAVLSFVALICIYLLYLWVLRDLILVLKARRGRSTEELIFGSEAVDRRSPIPNTLEPTAPVHPGPFVPGSG
What is the function of this protein?
Involved in the viral transport within, and between cells.
What are the official names of this protein?
Movement protein, MP.
What is the protein family that this protein belongs to?
Belongs to the mastrevirus movement protein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: IL7_SHEEP
Sequence: MFHVSFRYIFGIPPLILVLLPVASSDCDFSGKDGGAYQNVLMVSIDDLDNMINFDSNCLNNEPNFFKKHSCDDNKEASFLNRAARKLKQFLKMNISDDFKLHLSTVSQGTLTLLNCTSKGKGRKPPSLGEAQPTKNLEENKSLKEQRKQNDLCFLKILLQKIKTCWNKILRGITEH
What is the function of this protein?
Hematopoietic cytokine that plays an essential role in the development, expansion, and survival of naive and memory T-cells and B-cells thereby regulating the number of mature lymphocytes and maintaining lymphoid homeostasis.  Mechanistically, exerts its biological effects through a receptor composed of IL7RA subunit and the cytokine receptor common subunit gamma/CSF2RG.  Binding to the receptor leads to activation of various kinases including JAK1 or JAK3 depending on the cell type and subsequently propagation of signals through activation of several downstream signaling pathways including the PI3K/Akt/mTOR or the JAK-STAT5.
What are the official names of this protein?
Interleukin-7, IL-7.
What is the protein family that this protein belongs to?
Belongs to the IL-7/IL-9 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSRP_SALPK
Sequence: MDNVVDRHVFYISDGTAITAEVLGHAVMSQFPVTISSITLPFVENESRARAVKDQIDAIYQQTGVRPLVFYSIVLPEIRAIILQSEGFCQDIVQALVAPLQQEMKLDPTPIAHRTHGLNPGNLNKYDARIAAIDYTLAHDDGISLRNLDQAQVILLGVSRCGKTPTSLYLAMQFGIRAANYPFIADDMDNLTLPTSLKPLQHKLFGLTIDPERLAAIREERRENSRYASLRQCRMEVAEVEALYRKNQIPCLNSTNYSVEEIATKILDIMGLNRRMY
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: TRPF_CHLMU
Sequence: MKVKICGVTHPDDAWEAAKAGADYVGMIFAKDSQRCVTKETAKCIVEAIRDGGSEPVGVFSEHSIGEIIAISSATGITSIQLSGRNIDFKFSQLRELFSIFYVVSVYSNGQPSAAIPPMSNTVTVIYDHIGGERGTPFDWRAFSPFQHDNWMLGGGVNPGNVGEAVRLLSPRGIDVSSGVERPGVLRKDVTLMQALIDSAKGVGNLTS
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: AEDO_MOUSE
Sequence: MPRDNMASLIQRIARQACLTFRGSSTGSEGPAPGFPENLSLLKSLLTQVRAEDLNIAPRKALPQPLPRNLPPVTYMHIYETEGFSLGVFLLKSGTCIPLHDHPGMHGMLKVLYGTVRISCMDKLDTGAGHRRPPPEQQFEPPLQPLEREAVRPGVLRSRAEYTEASGPCVLTPHRDNLHQIDAVDGPAAFLDILAPPYDPEDGRDCHYYRVVEPIRPKEASGSACDLPREVWLLETPQADDFWCEGEPYPGPKVLP
What is the function of this protein?
Plays a vital role in regulating thiol metabolism and preserving oxygen homeostasis by oxidizing the sulfur of cysteamine and N-terminal cysteine-containing proteins to their corresponding sulfinic acids using O2 as a cosubstrate (PubMed:17581819, PubMed:32601061).  Catalyzes the oxidation of cysteamine (2-aminoethanethiol) to hypotaurine (PubMed:17581819, PubMed:32601061).  Catalyzes the oxidation of the regulator of G-protein signaling 5 (RGS5) (PubMed:32601061).  Also oxidizes proteins RGS4 and interleukin-32 (IL32) (By similarity).
What are the official names of this protein?
2-aminoethanethiol dioxygenase, Cysteamine dioxygenase.
Protein: CLPP1_BACAN
Sequence: MNAIPYVVEQTKLGERSYDIYSRLLKDRIVIIGSEINDQVASSVVAQLLFLEAEDAEKDIFLYINSPGGSTTAGFAILDTMNLIKPDVQTLCMGFAASFGALLLLSGAKGKRFALPNSEIMIHQPLGGAQGQATEIEITAKRILKLKHDINKMIAEKTGQPIERVAHDTERDYFMTAEEAKAYGIVDDVVTKK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 1, Endopeptidase Clp 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C3H12_ARATH
Sequence: MSHHRRDSGGDVVHVIPTNNPPPDNWFPNLGDSAVWATEDDYNRAWAMNPDNTSGDNNGPPNKKTRGSPSSSSATTTSAASNRTKAIGKMFFKTKLCCKFRAGTCPYITNCNFAHTVEELRRPPPNWQEIVAAHEEERSGGMGTPTVSVVEIPREEFQIPSLVSSTAESGRSFKGRHCKKFYTEEGCPYGESCTFLHDEASRNRESVAISLGPGGYGSGGGGGSGGGSVGGGGSSSNVVVLGGGGGSGSGSGIQILKPSNWKTRICNKWEITGYCPFGAKCHFAHGAAELHRFGGGLVEEEGKDGVSPNPDTKQTVQNPKGLSDTTTLLSPGVPHNADASYHTGVALQRASSAVTQKPGIRTHQKWKGPAKISRIYGDWIDDIE
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 12, AtC3H12.
Protein: CTAA_BRUME
Sequence: MAATSAQHIGLQGHGTSRNDRDRRLVRYWLYAVFAVLIAIVMVGGATRMTGSGLSITEWKPIHGVIPPLNHAEWVEEFEKYQQIPQYQQINKGMSLAEFQYIFWWEWAHRLLARFVGFLVAVPLGFFWLTGRLKGGLKYRMLGLLALGGLQGAIGWWMVASGLSELTSVSQYRLAIHLTTACVIITAVFYIARGLVTYSERPAERSIQRFAGWIVFAVLVQIYLGGLVAGLHAGLTYNTWPLMDGAIIPSDLFTQAPWWRNLFENPKTVQFVHRMFAYTVLLLAILHAVQVWKNAPGTTHARRTIVLVGLVFIQAMIGIATLLMSAPLHLGLTHQFFALVVLAFAVAHWRATKGAYAA
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UPP_ACIB3
Sequence: MAIQEIRHPLIRHKLGLLRRADISTKNFRELAQEVTMLLTYEATKDLPVVDCEIEGWAGNVTTQRIAGKKITIVPILRAGIGMLDGVLNLIPSAKVSVLGLERDEATLEVRTYYKKLVPDVANRIAMIIDPMLATGNSLVAAIDVLKASGCKDIRVMVLVAAPEGIAKVEAAHPDIQLYTASIDNGLNEHGYIVPGLGDAGDKIFGSVQKD
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: NDHK_TRACE
Sequence: MTSIDFPLLNRRTQNSVISTTPNELSNWSRLSSLWPLLYGTSCCFIEFASLIGSRFDFDRYGLVPRSSPRQADLILTAGTVTMKMAPSLVRLYEQMPEPKYVIAMGACTITGGMFSTDSYSTVRGVDKLLPVDVYLPGCPPKPEAVIDAITKLRKKISREIYADRIRSHRTNRSFTTNHKFQVGRSSHTGNYDQGFLSKPPSISEIPPETFFKYKSQSSVSSHALVN
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit K, chloroplastic, NAD(P)H dehydrogenase subunit K, NADH-plastoquinone oxidoreductase subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: Y3162_PSESM
Sequence: MGAQWKVKHKEAAANAKGRTFGKLSKEIMIAARAGADPDMNSRLRLVVEQAKKASMPRETLERAIKKGAGLLGESVNFERLTYEGFAPHRVPVIVECLTDNINRTVSEIRVLFRKGQLGAAGSVSWDFLYQGMIEAVPTAPDADADEAAIEAGAQDCEPGEEGATLFLTEPTDMDAVCKALPQFGFAVQSAQLGYRPKSTVDGLSDEQMAEVEAFLEAIDNHDDVQNVYVGLAG
What are the official names of this protein?
Probable transcriptional regulatory protein PSPTO_3162.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WNT7A_MACFA
Sequence: MNRKARRCLGHLFLSLGMVYLRIGGFSTVVALGASIICNKIPGLAPRQRAICQSRPDAIIVIGEGSQMGLDECQFQFRNGRWNCSALGERTVFGKELKVGSREAAFTYAIIAAGVAHAITAACTQGNLSDCGCDKEKQGQYHRDEGWKWGGCSADIRYGIGFAKVFVDAREIKQNARTLMNLHNNEAGRKILEENMKLECKCHGVSGSCTTKTCWTTLPQFRELGYVLKDKYNEAVHVEPVRASRNKRPTFLKIKKPLSYRKPMDTDLVYIEKSPNYCEEDPVTGSVGTQGRACNKTAPQASGCDLMCCGRGYNTHQYARVWQCNCKFHWCCYVKCNTCSERTEMYTCK
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta-catenin signaling pathway (By similarity).  Plays an important role in embryonic development, including dorsal versus ventral patterning during limb development, skeleton development and urogenital tract development.  Required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation (By similarity).  Required for normal, sexually dimorphic development of the Mullerian ducts, and for normal fertility in both sexes.  Required for normal neural stem cell proliferation in the hippocampus dentate gyrus.  Required for normal progress through the cell cycle in neural progenitor cells, for self-renewal of neural stem cells, and for normal neuronal differentiation and maturation.  Promotes formation of synapses via its interaction with FZD5 (By similarity).
What are the official names of this protein?
Protein Wnt-7a.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Secreted.
Protein: L_SENDF
Sequence: MDGQESSQNPSDILYPECHLNSPIVRGKIAQLHVLLDVNQPYRLKDDSIINITKHKIRNGGLSPRQIKIRSLGKALQRTIKDLDRYTFDPYPTYSQELLRLDIPEICDKIRSVFAVSDRLTRELSSGFQDLWLNIFKQLGNIEGREGYDPLQDISTIPEITDKYSRNRWYRPFLTWFSIKYDMRWMQKTRPGGPLDTSNSHNLLECKSYTLVTYGDLVMILNKLTLTGYILTPELVLMYCDVVEGRWNMSAAGHLDKRSIGITSKGEELWELVDSLFSSLGEEIYNVIALLEPLSLALIQLNDPVIPLRGAFMRHVLTELQTVLTSRDVYTDAEADTIVESLLAIFHGTSIDEKAEIFSFFRTFGHPSLEAVTAADKVRAHMYAQKAIKLKTLYECHAVFCTIIINGYRERHGGQWPPCDFPDHVCLELRNAQGSNTAISYECAVDNYTSFIGFKFRKFIEPQLDEDLTIYMKDKALSPRKEAWDSVYPDSNLYYKAPESEETRRLIEVFINDENFNPEEIINYVESGDWLKDEKFNISYSLKEKEIKQEGRLFAKMTYKMRAVQVLAETLLAKGIGELFSENGMVKGEIDLLKRLTTLSVSGVPRTDSVYNNSKSSEKRNEGMKKKNSGGYWDEKKRSRHEFKATDSSTDGYETLSCFLTTDLKKYCLNWRFESTALFGQRCNEIFGFKTFFNWMHPVLERCTIYVGDPYCPVADRMHRQLQDHADSGIFIHNPRGGIEGYCQKLWTLISISAIHLAAVRVGVRVSAMVQGDNQAIAVTSRVPVAQTYKQKKNHVYEETTKYFGALRHVMFDVGHELKLNETIISSKMFVYSKRIYYDGKILPQCLKALTRCVFWSETLVDENRSACSNISTSIAKAIENGYSPILGYCIALYKTCQQVCISLGMTINPTISPTVRDQYFKGKNWLRCAVLIPANVGGFNYMSTSRCFVRNIGDPAVAALADLKRFIRADLLDKQVLYRVMNQEPGDSSFLDWASDPYSCNLPHSQSITTIIKNITARSVLQESPNPLLSGLFTETSGEEDLNLASFLMDRKVILPRVAHEILGNSLTGVREAIAGMLDTTKSLVRASVRKGGLSYGILRRLVNYDLLQYETLTRTLRKPVKDNIEYEYMCSVELAVGLRQKMWIHLTYGRPIHGLETPDPLELLRGTFIEGSEVCKLCRSEGADPIYTWFYLPDNIDLDTLTNGSPAIRIPYFGSATDERSEAQLGYVRNLSKPAKAAIRIAMVYTWAYGTDEISWMEAALIAQTRANLSLENLKLLTPVSTSTNLSHRLKDTATQMKFSSATLVRASRFITISNDNMALKEAGESKDTNLVYQQIMLTGLSLFEFNMRYKKGSLGKPLILHLHLNNGCCIMESPQEANIPPRSTLDLEITQENNKLIYDPDPLKDVDLELFSKVRDVVHTVDMTYWSDDEVIRATSICTAMTIADTMSQLDRDNLKEMIALVNDDDVNSLITEFMVIDVPLFCSTFGGILVNQFAYSLYGLNIRGREEIWGHVVRILKDTSHAVLKVLSNALSHPKIFKRFWNAGVVEPVYGPNLSNQDKILLALSVCEYSVDLFMHDWQGGVPLEIFICDNDPDVADMRRSSFLARHLAYLCSLAEISRDGPRLESMNSLERLESLKSYLELTFLDDPVLRYSQLTGLVIKVFPSTLTYIRKSSIKVLRTRGIGVPEVLEDWDPEADNALLDGIAAEIQQNIPLGHQTRAPFWGLRVSKSQVLRLRGYKEITRGEIGRSGVGLTLPFDGRYLSHQLRLFGINSTSCLKALELTYLLSPLVDKDKDRLYLGEGAGAMLSCYDATLGPCINYYNSGVYSCDVNGQRELNIYPAEVALVGKKLNNVTSLGQRVKVLFNGNPGSTWIGNDECEALIWNELQNSSIGLVHCDMEGGDHKDDQVVLHEHYSVIRIAYLVGDRDVVLISKIAPRLGTDWTRQLSLYLRYWDEVNLIVLKTSNPASTEMYLLSRHPKSDIIEDSKTVLASLLPLSKEDSIKIEKWILIEKAKAHEWVTRELREGSSSSGMLRPYHQALQTFGFEPNLYKLSRDFLSTMNIADTHNCMIAFNRVLQDTIFEWARITESDKRLKLTGKYDLYPVRDSGKLKTISRRLVLSWISLSMSTRLVTGSFPDQKFEARLQLGIVSLSSREIRNLRVITKTLLDRFEDIIHSITYRFLTKEIKILMKILGAVKMFGASQNEYTTVIDDGSLGDIEPYDSS
What is the function of this protein?
RNA-directed RNA polymerase that catalyzes the replication of viral genomic RNA.  The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N).  The replicase mode is dependent on intracellular N protein concentration.  In this mode, the polymerase replicates the whole viral genome without recognizing transcriptional signals, and the replicated genome is not caped or polyadenylated.
What are the official names of this protein?
RNA-directed RNA polymerase L, Protein L, Large structural protein, Replicase, Transcriptase.
What is the protein family that this protein belongs to?
Belongs to the paramyxovirus L protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: RS8_CLOBH
Sequence: MVMSDPIADLLTRIRNANVVRHEVVEVPSSNIKKAIANIMLTEGYIRDLEEYRDGSVDMLRITMKYGQNKERIITGLKRISKPGLRVYCRKDETPKVLNGLGVAVVSTSKGIVTDREARKLGVGGEVLCYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: PLHD1_MOUSE
Sequence: MFTSKSNSVSPSPSLEQADADALDISTKVQLYGVLWKRPFGRSSAKWSRRFFIIKESFLLYYSESERKSFETNKYFNIHPKGVIPLGGCLVEAREEPSMPYAMKISHQDFHGNVLLAAESEFEQTQWLEMLQESGKVTWKNAQLGEAMIKSLEAQGLQLAKEKQEYLDKLMEETEELCLQREQREELERLNQVLEAEKQQFEEVVQELRVEQEQIKRELELTARCLKGVEQEKKELRHLTESLQHTLEELSIEKKKTLEMLEEDKNQPQPLTNQSEQPPASDGLHSNLRQIEERMQELLAEKLLAEKRMKENEERSRALEEEREFYSSQSQALQNSLQELTAEKQQAERELKAEVKVRMDLERRLREAEAALRSLEQGLNSKVRNKEKEERMRADVSHLKRFFEECIRNAELEAKMPVIMKNSVYIHKAATRRIKSCRFHRRRSSTSWNDMKPSQSFMTSQLEANNIEELKEVAKRLSRDQRFRESIYHIMATQPGASALPRGGK
What are the official names of this protein?
Pleckstrin homology domain-containing family D member 1, PH domain-containing family D member 1.
What is the protein family that this protein belongs to?
Belongs to the PLEKHD1 family.
Protein: CCS1_SYNJA
Sequence: MVIPSLPLSRWLSPLRRYFRHELLPLLADLRLAIGLFLAIALLSAVGTVIEQEETVAFYQAHYPEHPALFGFLTWRLILKLGLDHVYRTSWFLALLILFGSSLAACSLTRQWPMLKVARRWSYLTRPHSFQRLPFWTYLPQRSLQGLPQRLRQRGYAVFQDGSRLYARKGLIGRFGPILVHVSLLLILLGAIWGSLAGFKAQALIPSGSVAAIEQVTGAGDLAHLPTWQIRVNRFWIDYAPDGRVKQFYSDLSILDGGQEVKRQTISVNHPLSYRGVTLYQADWSIDSIRIRLNNSPPFQIPVVPVPTQAGSKLWGAFVPTRPDLSEGLTLLLPDLQGTALLYDTQGQWIGSLRQGMSLALDEVAPQRFPNRLTLHLDEVIGATGLQIKSDPGIPLVYLGFGLLMLGVAMSYFSYSQVWALETEAGLYLGGKTNRALVSFEREFARLVEQQLLSSPPSPAKEPPPAARVGGTESLANG
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsB.
What is the protein family that this protein belongs to?
Belongs to the Ccs1/CcsB family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: YHBS_ECOLI
Sequence: MLIRVEIPIDAPGIDALLRRSFESDAEAKLVHDLREDGFLTLGLVATDDEGQVIGYVAFSPVDVQGEDLQWVGMAPLAVDEKYRGQGLARQLVYEGLDSLNEFGYAAVVTLGDPALYSRFGFELAAHHDLRCRWPGTESAFQVHRLADDALNGVTGLVEYHEHFNRF
What are the official names of this protein?
Uncharacterized N-acetyltransferase YhbS.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family.
Protein: PAL3_PHAVU
Sequence: MATITPQKGSQSEVGVSNTDPLNWGNAVESLKGSHLEEVKGMVAEYREAVIHVGGGETLTVSKVAAVANQYLQAKVDLSESAREGVDSSCKWIVDNIDKGIPIYGVTTGFGANSNRQTQEGLALQKEMVRFLNCAIFGYQTELSHTLPKSATRAAMLVRVNTLLQGYSGIRFEILEAITKLLNHNVTPILPLRGTITASGDLIPLSYIAALLIGRRNSKAVGPSGESLNAKEAFHLAGVDGGFFELKPKEGLALVNGTAVGSGVASMVLFEANILALLAEVLSAVFAEVMQGKPEFTDHLIHKLKYHPGQIEAAAIMEHILDGSSYVKNAKLQQPDPLQKPRKDRYALVTSPQWLGPQIEIIRFSTKSIEREINSVNDNPLIDVTRNKAVSGGNFQGTPIGVSMDNARLAVASIGKLIFAQFTELANDLYNNGLPSNLSVGRNPSLDYGFKASEVAMAAYCSELQYLANPVTSHVQSTEQHNQDVNSLGLISALKTVEAIEILKLMSSTYLVALCQAIDLRHLEEIFKNTVKNTVSRVALKTLTTEDKEETNPFRFSEEELLKVVDREYVFSYIDDPLNVRYPLMPKLKQVLYEQAHTSVINDKNVSLLVFEKIGAFEDELKSLLPKEVESARVAYENGNPATPNRIKECRSYPLYKFVREELGIRLLTGEKALSPDEEFEKVYTAMCQAKIIDPILECLEDWNGVPIPI
What is the function of this protein?
This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton.
What are the official names of this protein?
Phenylalanine ammonia-lyase class 3, Phenylalanine ammonia-lyase class III.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMFO_MOOTA
Sequence: MSDKVIIIGGGLAGSEAAWQAARRGMKVELWEMRPGKLTPAHSTGYLAELVCSNSLRADSLENAAGLLKAEMRQAGSLIMEVAAACRVPAGKALAVDREEFASRVTAILEAHPGITVIREEVQAIPDNGPVIIATGPLTSPAMVRALKEFTGAEYLYFYDAAAPIVTAESLDYSRIFKGSRYGRGEDDYLNCPLNKEEYEAFYQALVTAERHPRHEFEPEVVFEGCMPVEVMAARGPDTLRFGPMRPVGLIDPATGREPYAVVQLRQDNAAGTLYNLVGFQTSLKWGEQERVFRLIPGLREAEFVRFGVMHRNTYVNSPRLLQPTLQVKGYPWLFLAGQLTGVEGYIESAACGLVAGVNATRFARGEEPLIPPPATAHGALLHYITDPTHTPFQPMHINYGLLPPLEHRVKNRVERNRILAARALEIWNSSGEFSGN
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IFNA5_HUMAN
Sequence: MALPFVLLMALVVLNCKSICSLGCDLPQTHSLSNRRTLMIMAQMGRISPFSCLKDRHDFGFPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWDETLLDKFYTELYQQLNDLEACMMQEVGVEDTPLMNVDSILTVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSANLQERLRRKE
What is the function of this protein?
Produced by macrophages, IFN-alpha have antiviral activities.  Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
What are the official names of this protein?
Interferon alpha-5, IFN-alpha-5, Interferon alpha-61, Interferon alpha-G, LeIF G.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta interferon family.
What are the subcellular locations of this protein?
Secreted.
Protein: DSRB_ECO55
Sequence: MKVNDRVTVKTDGGPRRPGVVLAVEEFSEGTMYLVSLEDYPLGIWFFNEAGHQDGIFVEKAE
What are the official names of this protein?
Protein DsrB.
What is the protein family that this protein belongs to?
Belongs to the DsrB family.
Protein: RS8_CALBD
Sequence: MYVIDPIADMLTRIRNANNARHEIVDIPASKMKKAIAQILLEEGFIKDYEIIDDGKNGIIRIRLKYGPNKERAITGLKRISKPGRRVYAGKDELPRVLGGLGIAIISTSKGIMTDKKARKEGVGGEVLCYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: MED18_DEBHA
Sequence: MVHQLSLVSMVSHSNYVQTISTLQALTGLLTPQPISTYTLVTKPHDVFKPKFEPGKVNQIEQFYMRCVTTWNDETGNKFDLASPVLENDTDILVNRLFLGVDDRRNWTMQISDIPIAGKNQACSAQTIYESTLVHHHTKVMDKEKVQSDVSNESNMDIDDKDEDKKENIKKEESGEEVKGSGEEVKGSGEEVKGSGEEAKKSGEEAKEHSEGNASQTVKELVVLNRRDSFLQFLEDLGYDVINQFWMKGVRFFHGDIVIEIFKVFVRDDEKDAEKDKIRLKLLDPSNTFQIRTYINVPKSTDVELINQGTKDLLKLQEFLKNLIKLEIPDRMFMDSRVTYK
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 18, Mediator complex subunit 18.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 18 family.
What are the subcellular locations of this protein?
Nucleus.