PharMolix/UniProtQA huggingface dataset:
Protein: ZSA5B_HUMAN
Sequence: MAANWTLSWGQGGPCNSPGSDTPRSVASPETQLGNHDRNPETWHMNFRMFSCPEESDPIQALRKLTELCHLWLRPDLHTKEQILDMLVMEQFMISMPQELQVLVKVNGVQSCKDLEDLLRNNRRPKKWSIVNLLGKEYLMLNSDVEMAEAPASVRDDPRDVSSQWASSVNQMHPGTGQARREQQILPRVAALSRRQGEDFLLHKSIDVTGDPNSPRPKQTLEKDLKENREENPGLSSPEPQLPKSPNLVRAKEGKEPQKRASVENVDADTPSACVVEREALTHSGNRGDALNLSSPKRSKPDASSISQEEPQGEATPVGNRESPGQAEINPVHSPGPAGPVSHPDGQEAKALPPFACDVCNKSFKYFSQLSIHRRSHTGDRPFQCDLCRKRFLQPSDLRVHQRVHTGERPYMCDVCQKRFAHESTLQGHKRIHTGERPFKCKYCSKVFSHKGNLNVHQRTHSGEKPYKCPTCQKAFRQLGTFKRHLKTHRETTSQ
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger and SCAN domain-containing protein 5B.
What are the subcellular locations of this protein?
Nucleus.
Protein: TAAR6_HUMAN
Sequence: MSSNSSLLVAVQLCYANVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFGNLLVMISILHFKQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEELSDALNCIGGCQTVVNQNWVLTDFLSFFIPTFIMIILYGNIFLVARRQAKKIENTGSKTESSSESYKARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCAYYNSAMNPLIYALFYPWFRKAIKVIVTGQVLKNSSATMNLFSEHI
What is the function of this protein?
Orphan receptor.  Could be a receptor for trace amines.  Trace amines are biogenic amines present in very low levels in mammalian tissues.  Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative.  Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood.
What are the official names of this protein?
Trace amine-associated receptor 6, TaR-6, Trace amine receptor 6, Trace amine receptor 4, TaR-4.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GRPE_CAUSK
Sequence: MTDEQTPAEDVAFEADDASQEIEALKLEVAALKDQALRYAAEAENTKRRAERESNDARAYAIQKFARDLLGAADNLSRATAMSPRDSQDPAVTNYIIGVEMTEKELQGAFERNGLKKIDPAKGEKFDPHLHQAVMEQPSTEVAAGGVLQVLQAGYELMGRLVRPAMVAVAAKGSTGPGAPAEPAAAPNPYASNGADTGGSFDTKA
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECO_STRP6
Sequence: MQLTESLGIVLFNRNYREDDKLVKIFTEVAGKQMFFVKHISRSKMSSIIQPLTIADFIFKLNDTGLSYVVDYSNVNTYRYINNDIFRLAYASYVLALADAAIADNESDSHLFTFLKKTLDLMEEGLDYEILTNIFEIQILDRFGISLNFHECAICHRTDLPLDFSHRFSAVLCSEHYYKDNRRNHLDPNVIYLLSRFQKITFDDLRTISLNKDIKKKLRQFIDELYHDYVGIKLKSKTFIDNLVKWGDIMK
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: TRPD_BACLD
Sequence: MNELLKSCVNGRTLNEIEAHSIMRDMMTGSLSAAEIGGLLSVLAYRGETAEEITGFVRAMREQAHTIDGPEHVVDTCGTGGDGSSTFNISTAAAIIASSAGAKIAKHGNRSVSSKSGSADVLEYLGVSIQTSPEETIKSIERRNMGFLYAPSYHSSMKHVAGARKDLAFRTVFNLLGPLSNPMKAKRQVIGVYSIEKAKLMARALEAFEPEHVLFVSSRDGLDELSITSPTDVIELKGGKTYEYTVEPGDVGLPLGRLRDIQVATPEESGRLIVDILKNRGPDSAVHIAAFNAGAALYVAEQAADLKEGVALALEAVAGGEALNQLERLKQKEEELYA
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: CSRA_RUMCH
Sequence: MLVLSRKKDQSLMIGNDIELTIIDIQGDQVKIGLKAPKNVSIYRKELYLEIQEENKKAATADVVELDSIFKK
What is the function of this protein?
A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation.  Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
What are the official names of this protein?
Translational regulator CsrA.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCAP_MEASF
Sequence: MATLLRSLALFKRNKDKPPITSGSGGAIRGIKHIIIVPIPGDSSITTRSRLLDRLVRLIGNPDVSGPKLTGALIGILSLFVESPGQLIQRITDDPDVSIRLLEVVQSDQSQSGLTFASRGTNMEDEADQYFSHDDPISSDQSRFGWFENKEISDIEVQDPEGFNMILGTILAQIWVLLAKAVTAPDTAADSELRRWIKYTQQRRVVGEFRLERKWLDVVRNRIAEDLSLRRFMVALILDIKRTPGNKPRIAEMICDIDTYIVEAGLASFILTIKFGIETMYPALGLHEFAGELSTLESLMNLYQQMGETAPYMVILENSIQNKFSAGSYPLLWSYAMGVGVELENSMGGLNFGRSYFDPAYFRLGQEMVRRSAGKVSSTLASELGITAEDARLVSEIAMHTTEDKISRAVGPRQAQVSFLHGDQSENELPRLGGKEDRRVKQSRGEARESYRETGPSRASDARAAHLPTGTPLDIDTASESSQDPQDSRRSADALLRLQAMAGISEEQGSDTDTPIVYNDRNLLD
What is the function of this protein?
Encapsidates the genome in a ratio of 1 N per 6 ribonucleotides, protecting it from nucleases.  The nucleocapsid (NC) has a helical structure with either 12. 35 or 11. 64 N per turn, approximately 20 nm in diameter, with a hollow central cavity approximately 5 nm in diameter.  The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication.  During replication, encapsidation by N is coupled to RNA synthesis and all replicative products are resistant to nucleases.  N is released in the blood following lysis of measles infected cells, it interacts then with human FCGR2B on immune cells, inducing apoptosis and blocking inflammatory immune response.  Ntail binds to a protein on human thymic epithelial cells, termed Nucleoprotein Receptor (NR), inducing growth arrest.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, NP, Protein N.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses nucleocapsid family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: DABA_SALRD
Sequence: MPIDRSVVRARIENAAEYVGPLWPLRTFNAANPLLGFEDQPFDRAVQKAGQLFGGRGYPGPTVFRQAWENGEIDADVLTRHLAEHGITERPEVLLDRMDADAAGRDAAPADQPLDRVLTKWLAAFLDQGQAAWPMPNREDGFYAAWRTVAPYDGDIPGVGRPSDLPGTVVEAFEAVLESYPEARWEPIFVHHLTALPGWTGFIKWRSRRADTAWQAAHPISLTEYLAVRLTLADRMGAAIAPDRTDELPANGTDQPVLPRIWLRAWEESYRTRLLDDLRQTQQTTPSGSDAGRPDAQLVFCIDTRSEVIRRHIEQQGPYETHGYAGFFGVPMQHQPYGTEERVKSCPPIVDPKHRIMERPAEPHRAQAERYDWWARLQKAGAALLKTLKKNVAAVFGFVEGSGGFFGAAMAARTLAPSGLSRLDEALDDWLPGPASFCEPTVDRAPPADADAEDGLPVGLADEAKVLYAEAAFRLMGWTDTFAPVVVFTGHGSQTPNNPYKASLDCGACAGNPGGPNARVLAAICNEDAVQEALRERGIAIPDDTVFLAGQHNTTTDEIALFVDEDDPPVAPDALDRLRRDLHAAQADAATERVRTLNTSVDEGRPAAAVRETERRAADWAETRPEWGLAGNAAFIVGPRALTRGLDLDGRCFLHSYDWATDDDGTALENIMTGPLVVGEWINTQYYFSTVDNAAYGSGSKVTQNVVGKLGVVQGNGGDLMSGLPLQSLKADDEHVHHRPLRLMALIQAPTDRVEAILDRHAAVAHLFDHEWMHLTVMDPEQDDAFVRYKPGGGWHARPAPDASTATKAPASAGVPS
What is the function of this protein?
Part of an energy-coupled inorganic carbon pump.
What are the official names of this protein?
Probable inorganic carbon transporter subunit DabA.
What is the protein family that this protein belongs to?
Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y16M_BPT4
Sequence: MLIFALGSVVVGIYLMAVVGMDIHQNGLKSVVETIWNGVK
What are the official names of this protein?
Uncharacterized 4.3 kDa protein in ndd-denB intergenic region.
Protein: PA2B9_PSEAU
Sequence: NLIQFKSIIECANRGSRRWLDYADYGCYCGWGGSGTPVDELDRCCKVHDECYGEAVKQGCFPKLTVYSWKCTENVPICDSRSKCKDFVCACDAAAAKCFAKAPYNKDNYNIDTKTRCQ
What is the function of this protein?
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Basic phospholipase A2 PA-9C, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DEF1_CANAL
Sequence: MSTYRKTYKNQSKRFNNGNNSNSTSTELTNLVEMFPDWEADELQGLLSENDNSLEIVIDLIVNNKVSKWEPIKKEKHKKKEHKDDTTDSVTGNANGASNSGSSNSTTASGDRRLNNKAKASTSSRPPKRQQHPNAAHKKNEKTERSKASTVSTTTTSATSSVTKESVPPSNSWAAALSNDKPKKQETKSEASESIPSSNDGGDAETVPEVEQAETLEESHQEPENVEEPIESVSEQSQPENTKPVLKSAAIPEPKQGSWASAIAPKTKPKPKTVSKPVPQPEESKPEEHIPVQEEAQPVESILEDKPAVEAVQPVQPPVEDEPVEAPAASSVAAVADASFSEPTASSIIDQQPQVVLPTTQQQVDSVGISFGSLSVDAGEPKEAAEVIQDETISEQVQPEQQQQSQQQPLQEQQRYGLYNQQPTQQRYQQNNYQQQGQYSKQQQQQQQQQTSQPTQQQQQYDYYGQYQQQQYPQQTAQPGAQFGGYPGFDYNAYNQQAFAAAAAASPAASHVATIGGGVGGYNQYAQQANSADSTQSPIVNQSTLQQQQAAVLAAQQQQQQLPTPFGYPAYYNYYYNNPYFNAGGLGSTGFSAPQQGTQQGTQQQQSQQSGQQQQQVSSANQQGSVSSNSFGAQQQYYNPNQFNSRYPGYSYPPQQQNQQSSQHTSGQSQQGAQTTSDGASDGQQTSQQGQSSQQPQQQQQQHAQPVPQQHMMPQYGAYQQYPQYGYQDSNQYRGGWY
What is the function of this protein?
Recruits the ubiquitination machinery to RNA polymerase II for polyubiquitination, removal and degradation, when the transcription-coupled repair (TCR) factor RAD26 fails to efficiently displace stalled RNA polymerase II.  Also involved in telomere length regulation.  Binds DNA.
What are the official names of this protein?
RNA polymerase II degradation factor 1.
What is the protein family that this protein belongs to?
Belongs to the DEF1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: FBL8_ARATH
Sequence: MNIYIFSKEKKRKKVVCDNLSKTRGSRREHCEPHRRRMGQSTSKFRRSKTTFTSPVLPNLREQNSGADEPYDYISNLPDECLSLIFQSLTCADLKRCSLVCRRWLTIEGQCRHRLSLKAQSDLISVIPSLFTRFDSVTKLVLRSDRRSLGICDNAFVMISVRCRNLTRLKLRGCPEISDLGIIGFTENCRSLKKVSFGSCGFGVKGMNALLNTCLGLEELSVKRLRGIGAGAELIGPGGAAGSLKVICLKELHNGQCFAPLLSGAKGLRILKIFRCSGDWDRVFEAVRDKVNAIVEIHLERIQMSDLGLTALSKCSGVEVLHLVKTPDCTNVGLALVAERCKLLRKLHIDGWKTNRIGDEGLIVVAKYCWNLQELVLIGVNPTKLSLEAIVSNCLNLERLALCGSDTVGDTELCCIAEKCLALRKLCIKNCPITDDGIKALGNGCPNLLKVKVKKCRGVTTQGADLLRKRRALLVVNLDAPETPIVEGSVGEGGAQENAVEFPPSRLQIPTIGLASGSTSRSSSFKLRLGFLSQRNFVSCALRRLGSRSRSRNE
What are the official names of this protein?
Putative F-box/LRR-repeat protein 8.
Protein: AUSG_EMENI
Sequence: MAMGNPELRTHFFRSSHEPGIPNSLRFPNGFLVTCGLPWLLLLFSVTIILFHPLRKKSDLPLINPGKGRIGILRGYRSRKTFTTELPRLVADGLSKASAFRIAAPDGVNIVLAPSYAHEIAEHPDLNPGPIAGDEFNSHINGFEVFAQLGTSDVISESVRTRLTRQLTKLTPLLTSETPLLLQSQWKDAPDWVEVSPHETALFILSRLSSLVFVGDDLGRNPDWIRILTSYNTEAFAAAEELNLWPQILRPLIARLKPSCRQLRRYIRDARALLVPVLEQRRHAQSQGDRREYNDAIEWLDETSRSTGQPYDPILSQMLLAIGSFHTSSDLLGQVLLDLCMRPDWKVLVRELRKEIISSLQGEGWDKIALNNLKLMDSVLKESQRLKPASTVTMGRYASREITLSDGTIIPKGSTVFIANVAMRDSNIYPDPDDFVPDRFTTRREKGDSSAYLVSASPEHLGFGLGRHACPGRFFAANELKIVLSHMLMKYDIKLPDNGAVAPSKSGIFLATNPDARICVRRRKEEIVI
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster B that mediates the biosynthesis of austinol and dehydroaustinol, two fungal meroterpenoids (PubMed:22329759).  The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid by the polyketide synthase ausA (PubMed:22329759).  3,5-dimethylorsellinic acid is then prenylated by the polyprenyl transferase ausN (PubMed:22329759).  Further epoxidation by the FAD-dependent monooxygenase ausM and cyclization by the probable terpene cyclase ausL lead to the formation of protoaustinoid A (PubMed:22329759).  Protoaustinoid A is then oxidized to spiro-lactone preaustinoid A3 by the combined action of the FAD-binding monooxygenases ausB and ausC, and the dioxygenase ausE (PubMed:22329759, PubMed:23865690).  Acid-catalyzed keto-rearrangement and ring contraction of the tetraketide portion of preaustinoid A3 by ausJ lead to the formation of preaustinoid A4 (PubMed:22329759).  The aldo-keto reductase ausK, with the help of ausH, is involved in the next step by transforming preaustinoid A4 into isoaustinone which is in turn hydroxylated by the P450 monooxygenase ausI to form austinolide (PubMed:22329759).  Finally, the cytochrome P450 monooxygenase ausG modifies austinolide to austinol (PubMed:22329759).  Austinol can be further modified to dehydroaustinol which forms a diffusible complex with diorcinol that initiates conidiation (PubMed:22234162, PubMed:22329759).  Due to genetic rearrangements of the clusters and the subsequent loss of some enzymes, the end products of the Emericella nidulans austinoid biosynthesis clusters are austinol and dehydroaustinol, even if additional enzymes, such as the O-acetyltransferase ausQ and the cytochrome P450 monooxygenase ausR are still functional (PubMed:29076725).
What are the official names of this protein?
Cytochrome P450 monooxygenase ausG, Austinoid biosynthesis clusters protein G.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RS2_PROM1
Sequence: MAVVSLSEMMEAGAHFGHQTRRWNPKMSRYIYSARNGVHIIDLVKTAVCMNSAYKWTRGAARSGKRFLFVGTKKQASEVVAQEAIRCGASYVNQRWLGGMLTNWTTMKARIDRLKDLERMESSGAIAMRPKKEGAVLRRELERLQKYLGGLKGMRRLPDVVVLVDQRRETNAVLEARKLDIPLVSMLDTNCDPDLCEIPIPCNDDAVRSVQLVLGRLADAINEGRHGPNE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RRP8_SCHPO
Sequence: MFKVDWDLGPVSKSASDQTKESRKEKKRKKGERKNVGDKGEKLNEKVLKKAKSVTTNNSLKSEIKKEKSVPSIKEKNKGDAKHTKLTSLQQKMKDKLDGANFRWINEQLYTTESDKAVQMFKENPDLFDIYHAGFRYQVEGWPENPVDIFIQHLKIRFEHSNAKKKNNIVIADLGCGEAKIASTFRKSRSLQVHSFDLVAPNEHVVACDIANVPMADETVDIAVFCLSLMGTNWQSFLKEAYRILKVGGLLWVAEIKSRFSDKSGEVFAKELPKLGFETKSIQLQNKMFTLFEFKKVPVHGKCEELPPILSACIYKRR
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25. 1 in 25S rRNA.  Required both for ribosomal 40S and 60S subunits biogenesis.  Required for efficient pre-rRNA cleavage at site A2 (By similarity).
What are the official names of this protein?
25S rRNA (adenine(645)-N(1))-methyltransferase, Ribosomal RNA-processing protein 8.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RRP8 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: NLP8_PHYCP
Sequence: MRLSIALGAVLTVLIAVQGEETTNSTTKYIDYSSLKKFTLAPTIQQSSTDGSQVQQIQIPISTRPDPRATEAPTPAPTLAPTPAPTPTPTPDPGPWTTITIDHDQVKPFAQPEPVTISEKTAVKFKPQLHITNGCHSYPAVDEAGETGGGLKTKGAPSAGCKGSGWGSQVYGRSGWYQDVWAIMYCWYFPKDEPSSGIGHRHDWEHVIVWIDNPAVENPKILAVTPSAHSGYHKYAPPNADTIDGVTTKVAYDSKWPMDHALDSTSEAGDFQDLIMWDQLSENARRALNSVNFGRPNTPMNDGNFQPKLAKAWPFQ
What is the function of this protein?
Secreted effector that contributes moderately to virulence during infection by P. capsici.  Does not cause visible reaction of C. annuum for several days after inoculation, but by 7 days after inoculation, small necrotic lesions become visible.  Leads only to chlorotic areas, without necrosis at 7 days after non-host N. benthamiana leaves infection.
What are the official names of this protein?
NLP effector protein 8, Necrosis-inducing protein 8, Nep1-like protein 8.
What is the protein family that this protein belongs to?
Belongs to the Necrosis inducing protein (NPP1) family.
What are the subcellular locations of this protein?
Secreted.
Protein: HEM6_VIBC3
Sequence: MESIVDKQAVKHFLLQLQDKICQQLEATDGQAQFIEDAWQREPGEKLGGGGRTRVMREGAVFEQGGVNFSHVFGEQMPASATAHRPELAGRRFEAMGVSLVMHPKNPYVPTSHANVRFFIAEKEGEAPIWWFGGGFDLTPFYPFVEDGQHWHQTAKNICAPFGSEIYNEHKAWCDRYFYLPHRNETRGIGGLFFDDLNEWSFEQCFAYMQAVGEGYTQAYVPIVEKRKNTPFTERERQFQLYRRGRYVEFNLVLDRGTLFGLQTGGRTESILMSMPPLARWEYAYQPQAGTPEAKLSEFLVPREW
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMG_YERPS
Sequence: MSQLDLGTQSLELERFPPQENSNTLQAWEAADEYLLQNIDLSQIDGRPVLVFNDQFGTLACALHAYRPFSSSDSYMSQLATAHNLRLNHLDESAVTLLSSVDDLPEAPKLVVIKIPKALALLEHQLRALRRVVAPDTVIIAGAKSRDVHNSTLQLFEKILGPTKTTLAWKKARLIHCEVADIPLADAPETIDWPLPNTDYIIHNHANVFSRNNLDIGARFFMEILPYDVTGKIADLGCGNGVVGLIALEQNPLAEMLFVDESYMAVASSELNITVNRPQDLSRCEFMVSHGLAGVERESLQLVLCNPPFHQQHAVSDHVAWQMFCDAKRCLKAGGELMIVGNRHLDYFHKLKRLFGNCETLDSNQKFMVLKSVKQASSRSEGGGSGSLDMSYSDF
What is the function of this protein?
Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase G, 23S rRNA m2G1835 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RlmG.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEXA_GLUOX
Sequence: MLTRKQHQLLLYIDDHLRRTGYSPSFDEMKDALELRSKSGIHRLISALEERGFLRRHHHRARALEVLRLPHMGTEAPAATGTGTAFVPAVLNQGQTGLEGAFSEASVANDRQTVSIPLYGRIAAGLPIEAMQDDSDRIDVPVSLLGTGEHYALTVAGDSMIEAGILDGDIAIIRRRETAENGQIIVALIDEQEVTLKKLRRRGSMIALEAANRDYETRIFPAERVHIQGRLVALFRQY
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: LEC_ONOVI
Sequence: AENTVSFDFSKFLSGQENLILQGDTVTDDSNRCLVLTRENNGRPVQDSVGRVLYQTPIHLWDKQIDKEASFETSFTFFIYRENINRGGDGITFFLAPTDTQPKSGGGYLGIFKDAESNETVVAVEFDTFSNRWDPANSHIGINVNSVKSKITTPWGLKNDYFTVTITYDATRSLSVSSFYRNKPDDIFTVKASVHLRDALPQWVRIGLSAATGDLVEQHRLYSWSFKSVLPLDSST
What is the function of this protein?
D-mannose and D-glucose specific lectin.
What are the official names of this protein?
Lectin.
What is the protein family that this protein belongs to?
Belongs to the leguminous lectin family.
Protein: MDH_MYCTU
Sequence: MSASPLKVAVTGAAGQIGYSLLFRLASGSLLGPDRPIELRLLEIEPALQALEGVVMELDDCAFPLLSGVEIGSDPQKIFDGVSLALLVGARPRGAGMERSDLLEANGAIFTAQGKALNAVAADDVRVGVTGNPANTNALIAMTNAPDIPRERFSALTRLDHNRAISQLAAKTGAAVTDIKKMTIWGNHSATQYPDLFHAEVAGKNAAEVVNDQAWIEDEFIPTVAKRGAAIIDARGASSAASAASATIDAARDWLLGTPADDWVSMAVVSDGSYGVPEGLISSFPVTTKGGNWTIVSGLEIDEFSRGRIDKSTAELADERSAVTELGLI
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: MTNA_LEPIC
Sequence: MQESGLKPILWKNKELILLDQRVLPGTTSYITAKTLEDCIFAIREMVVRGAPAIAITGAFGITLYWNSLVSKPSFSELKLKLSELLESRPTAVNLRLAIEEFSSRFPESNYSSFSLEEIQKGAEELALFMLSEDLENNLTLSKYALSLFPKQPSSLNIITHCNTGALATAGHGTALGVIRSLRDAGHSLTVFADETRPYLQGARLTAWELQEEKIQSFLITDNMAGWVMSSRKIDAVIVGADRIASNGDTANKIGTYPLAIVAKHHGVPFYVAATAKSMDFRIPNGSYIPIEMRKEEEITSFGFLKDSDGKPLLKEGVIAPKGMKALNPSFDVTPASLITGIITEKGIVSPVTEENLKKIFQSI
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: CBID_TOLAT
Sequence: MNIALADDKVWHKGKSYRKGYTTGSCATAAAKVATLMILRQQVIHQVSIVTPSGVTLQLNVEEPLIHGLQASAAIRKDGGDDVDATHGMLIYAQVVLRNDATITISGGTGVGKVTRKGIGLPVGNAAINKTPLQTIEAAVREVLGPERGADITIFAPEGEERAQRTYNGRLGIEGGISIIGTTGIVTPMSEESWKRSLALELEQKRAQGMEKIILVPGNHGERFVREQMQLDSELVVTMSNFVGYMLQEAERLAFRHVVLIGHLGKLIKVAAGIFHTHSHIADGRMETLITHLALLGAPNSLLQAIYACNTTEAAMELIEAQGYQEVYNTIATRICERINQMLRYSPQPFQCDAILFSLDNQPLGSNRPITDIVEALR
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: CSTR3_ORYSI
Sequence: MSGEVECRVCHAKVQVPMAAAAVSKAYDIHRSSVSSRQRALNVLLVSGDCVLAGLQPILVYMCKVDGKFKFSPVSVNFLTEITKIIFAIIMLCIQARRLKVGEKPFLTVSTFMQAARNNVLLAVPALFYAINNYMKFVMQLYFNPATVKMLGNLKVLVIAVLLKVIMRRRFSTIQWEALALLLIGISVNQLKSLPEGSSTLGLPVAAGAYLYTLFFVTVPALASVYNEKALKSQFDTSIYLQNLFLYGYGAIFNFLGLVITAIIQGPSSFNILEGHSKATMFLICNNAAQGILSSFFFKYADTILKKYSSTIATIFTGVASAVLFGHTLTINFVLAISIVIISMHQYLSNQIKDEVPSSKIEMGDAHEHRSKESVVVNVSDSIATEAKHRHGTDERQPLLPV
What is the function of this protein?
Sugar transporter involved in the transport of CMP-sialic acid from the cytoplasm into the Golgi.  May transport important nucleotide sugars such as CMP-Kdo (2-keto-3-deoxy-D-manno-octulosonic acid) in physiological conditions.
What are the official names of this protein?
CMP-sialic acid transporter 3, CMP-SA-Tr 3, CMP-Sia-Tr 3, CMP-sialic acid transporter-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the nucleotide-sugar transporter family. CMP-Sialate:CMP antiporter (TC 2.A.7.12) subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: SYDND_HELPG
Sequence: MRSHFCTEISEKDVGKTIKVAGWCNTYRDHGGVVFIDLRDKSGLVQLVCDPSSKAYEKALEVRSEFVLVAKGKARLRGPGLENPKLKTGKIEIVLEELVIENKSATPPIEIGNKSVNEDLRLKYRYLDLRSPNSYEIFKLRSEVALITRNTLAQKGFLEIETPILSKTTPEGARDYLVPSRVHEGEFFALPQSPQLFKQLLMVGGMDRYFQIARCFRDEDLRADRQPEFTQIDAEMSFCDENDVMGVVEDLLQAIFKAIGHTISKPFKRMPYKEAMENYGSDKPDLRFKLPLIEVGDCFMDSSNAIFSNIAKDPKNKRIKALNVKGADALFSRSVLKELEEFVRQFGAKGLAYLQIKEDGIKGPLVKFLSEKGLKNILEKTGAKTGDIVFFGAGDKKIVLDYMGRLRLKVAETLDLIDKDALNFLWVVNFPMFEKTENGYHAAHHPFTMPKNIECEDIEEIEAHAYDVVLNGVELGGGSIRIHKEEMQKKVFEKINIHEEEAQKKFGFLLEALKFGAPPHGGFAIGFDRLIMLMTKSHSIRDVIAFPKTQKASCLLTNAPSPINEEQLRELHIRLRK
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.