PharMolix/UniProtQA huggingface dataset:
Protein: TRM2_HHV2H
Sequence: MAGRAGRTRPRTLRDAIPDCALRSQTLESLDARYVSRDGAGDAAVWFEDMTPAELEVIFPTTDAKLNYLSRTQRLASLLTYAGPIKAPDGPAAPHTQDTACVHGELLARKRERFAAVINRFLDLHQILRG
What is the function of this protein?
Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging.  Forms a tripartite terminase complex together with TRM1 and TRM3 in the host cytoplasm.  Once the complex reaches the host nucleus, it interacts with the capsid portal vertex.  This portal forms a ring in which genomic DNA is translocated into the capsid.
What are the official names of this protein?
Tripartite terminase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae TRM2 protein family.
What are the subcellular locations of this protein?
Host nucleus. Note=Found associated with the external surface of the viral capsid during assembly and DNA packaging, but seems absent in extracellular mature virions.
Protein: SYL_GLOVI
Sequence: METRYNPHAIEPRRQKQWEEAPHLAMDGRPKFYALSMFPYPSGALHMGHVRNYSITDVISRYKRMRGFNVLHPIGWDAFGLPAENAAIDRGIHPAQWTEQNIAQMREQLKRLGFAYAWEREVATCSPAYYRWTQKLFLEFWKAGLAYRKAGVVNWDPVDQTVLANEQVDAEGRSWRSGALVEKRPLEQWYLKITDYAEELLQALGTLGDWPERVRVMQENWIGKSVGAELCFPINGEPEGIRVFTTRPDTVYGVTYLVLAPEHPLVERITAPERREAVRAFVAQVQSESEIERVSEDRPKQGVSTGAVALNPFTGQAVPVWIADYVLFEYGTGAVMGVPGHDERDFVFASQYELPIRLVVQAPDGSLTEPLRAAYTEVGVLVNSGPFNGLDSPTGKLKIVEYAEQQGWGKGRVQYRLRDWLISRQRYWGCPIPMVYCPECGVVPVPDEQLPVALPGDVEFSGRGPSPLAKLEGWICVDCPQCGAPARRETDTMDTFIDSSWYFLRFADARNGAEPFSREAVDYWLPVDQYVGGIEHAILHLLYSRFFTKVLRDRGLLSFDEPFKRLLTQGMVLSNAFVDPATKKYYPPDQVEERGGAFFARPDGTPLVCAMEKMSKSKYNGIDPLTVRSEYGADTARLFVLFKAPPEKELEWSDADVRGQYSFLGRVWRTVYEFVSGEKPDRPVGEAQERDLRREVHRAIQQVGGDIEQYKFNTAIAALMKLNNAMADYPSGQSPAYKEGVYVIVKLLAPFAPHIGAELWQALGEAGDIHTSDWPALDESALVEETIVLVIQVNGKKRDDIQVPAAASEGELQELALASEAVRRHTDGKAIKKVIVVPGRLINLVVG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSPL8_PHYPA
Sequence: METGDSAVKSSQDVHYYGKSTAQKHRRSNGIILIFRALTFSFSLTSVIVMGTNRHRIDAQSRVAWYDFDPFRYVLAVNAIICIYSFVEIWLAVYTYLKDTLFLPETFQVWFDYGHDQGFAYLLFSANSAGIAMAQLLQSGNSLIHGAYRCSDAGVFCTQARASIGLGFGAFLFLALSSLLTGLRVARWYFS
What are the official names of this protein?
CASP-like protein 4C3, PpCASPL4C3.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MDH1_ALBFT
Sequence: MSKKPVRVAVTGAAGQIGYAILFRIASGEMLGKDQPVILQLLEVPVEKAQQALQGVMMELQDCAFPLLAGMEAHSDPMTAFKDVDYALLIGSRPRGPGMERAELLAVNGAIFTAQGKALNAVASRNVKVLVVGNPANTNAYIAMKSAPDLPAKNFTAMLRLDHNRALSQLASKTGKAVADIEKMAVWGNHSPTMYADYRFATINGESVKDMINDQDWNANTFLPTVGKRGAAIIAARGVSSAASAANAAIDHMRDWALGTNGKWVTMGIPSDGQYGIPKETMFGFPVTCEGGEYKVVQNLPIDAFSQECINKTLKELQDEQAGVAHLL
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase 1.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: RNH2_MOOTA
Sequence: MRASAGERERVEALYAWERRLQRQGVARIAGVDEAGRGPLAGPVTAAAVILPPGLFIAGLNDSKKVPPARRRELAAVIKKESLAWGIGWVSVKEIDCLNILAASRWAMRRALSALAIRPDHVLIDGMELPGLKIPQTPLVGGDALSASIAAASILAKVARDELMVAYDAVFQGYGLAGNKGYPTREHREALRRLGPCALHRRSFKH
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: JIP5_ASPOR
Sequence: MFDTVCTLPLSADLFAQAIHPKEPIVSVGLASGHVETFRLPSDEVDSDDDQASTSSSRNGRGHIDTMWRTRRHKGSCRCLTFGIDGESLYSAGTDGLVKAAKAETGVVENKIAIPPEKDGSVDAPTVIHALSPQTLLLATDSSALHLYDLRLPFSRVSARPQQSHHPHDDYISSITPLPASDTSTSGFSKQWVSTGGTTLAVTDLRRGVMVRSEDQEEELISSVYVGGLATTGTSRGEKVIVGGSSGVLTLWEKGAWDDQDERIYVQRSGGEGESLETLAMVPDELGRGKMVAVGLGSGGVKFVRIGPNKVVSEVTHDETEGVVGLGFDVEGRMVSGGGQVVKVWHEAVGSGANGASAGEKHMLGDSDEDSDDDDNDDSDDSDGERRRADEAKRKRKKGKGKDRSGGQHVMAFYDLD
What are the official names of this protein?
WD repeat-containing protein jip5.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR55 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: KGUA_CHLCV
Sequence: MKDKVRVPFSPDHPSCAPKLFTISAPAGAGKTTLVRMLAQEFPDSFQKTLSLTTRAPRPEEVSGIDYWFVSQEEFKQRLDSNNFLEWVLLFGEYYGTSRLEIDEIWKSGKHAVAVIDVEGALSLKSKIPTVTIFISAPSQEELERRLKYRGSEQDSQRQERLQHSLIEQAASNQFEYVIINDDLQKSYEILKSIFIAEEHRNVL
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRE11_YEAST
Sequence: MDYPDPDTIRILITTDNHVGYNENDPITGDDSWKTFHEVMMLAKNNNVDMVVQSGDLFHVNKPSKKSLYQVLKTLRLCCMGDKPCELELLSDPSQVFHYDEFTNVNYEDPNFNISIPVFGISGNHDDASGDSLLCPMDILHATGLINHFGKVIESDKIKVVPLLFQKGSTKLALYGLAAVRDERLFRTFKDGGVTFEVPTMREGEWFNLMCVHQNHTGHTNTAFLPEQFLPDFLDMVIWGHEHECIPNLVHNPIKNFDVLQPGSSVATSLCEAEAQPKYVFILDIKYGEAPKMTPIPLETIRTFKMKSISLQDVPHLRPHDKDATSKYLIEQVEEMIRDANEETKQKLADDGEGDMVAELPKPLIRLRVDYSAPSNTQSPIDYQVENPRRFSNRFVGRVANGNNVVQFYKKRSPVTRSKKSGINGTSISDRDVEKLFSESGGELEVQTLVNDLLNKMQLSLLPEVGLNEAVKKFVDKDEKTALKEFISHEISNEVGILSTNEEFLRTDDAEEMKALIKQVKRANSVRPTPPKENDETNFAFNGNGLDSFRSSNREVRTGSPDITQSHVDNESRITHISQAESSKPTSKPKRVRTATKKKIPAFSDSTVISDAENELGDNNDAQDDVDIDENDIIMVSTDEEDASYGLLNGRKTKTKTRPAASTKTASRRGKGRASRTPKTDILGSLLAKKRK
What is the function of this protein?
Involved in DNA double-strand break repair (DSBR).  Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity.  Also involved in meiotic DSB processing.
What are the official names of this protein?
Double-strand break repair protein MRE11.
What is the protein family that this protein belongs to?
Belongs to the MRE11/RAD32 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS4_DINSH
Sequence: MILYPAIDLKDGQAVRLYKGDMDKATVFNDSPAAQARAFQDAGCAWLHLVDLNGAFAGAPVNAAAVEAILAETSVPAQLGGGIRDMATIEMWLGKGIARVILGTVAVEDPELVRAAAKAFPGQVAVGLDARAGRVATRGWAEETDLMVTDLARSFEDAGVAAIIYTDIDRDGAMQGPNVAATAALARATSIPVIASGGVSSLDDLRALKASGAPLDGAISGRALYDGAIDLAEALAVLAD
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADA_ALKMQ
Sequence: MNETNMIDEIKRLKKEKNAVILAHNYQIPEIQEIADIVGDSLKLSQEATKTDADIVVLSGVKFMAESVKILSPNKKVLLPAHDAGCPMADMIDVDQLKEFKAEYPNVPVVCYVNSSAEVKAESDICCTSSNAIKVVRSLQSDKVIFVPDQNLAAYIAEQVPEKEIIPWQGFCITHHRVKDLEVDKIRKQMPEAVFLVHPECTPDVVKKADFVGSTSQIIQYAKESNAEKFVIGTEMGVLHKLKKENPTKKFYLLSPGLICFNMKKTTLVNVYEALRDEQHEIIVDEYVREKALKTLNQMLEIK
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARNC_SHIDS
Sequence: MFEIHPVKKVSVVIPVYNEQESLPELIRRTTTACESLGKEYEILLIDDGSSDNSAHMLVEASQAENSHIVSILLNRNYGQHSAIMAGFSHVTGDLIITLDADLQNPPEEIPRLVAKADEGYDVVGTVRQNRQDSWFRKTASKMINRLIQRTTGKAMGDYGCMLRAYRRHIVDAMLHCHERSTFIPILANIFARRAIEIPVHHAEREYGESKYSFMRLINLMYDLVTCLTTTPLRMLSLLGSIIAIGGFSIAVLLVILRLTFGPQWAAEGVFMLFAVLFTFIGAQFIGMGLLGEYIGRIYTDVRARPRYFVQQVIRPSSKENE
What is the function of this protein?
Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase, Undecaprenyl-phosphate Ara4FN transferase, Ara4FN transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSBZ_PHATC
Sequence: MITALTALLVLISLGLIVTVPVALATPGEWENSKSDFTKGFQAWVALVLVIAAADGVASSL
What is the function of this protein?
Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna.
What are the official names of this protein?
Photosystem II reaction center protein Z, PSII-Z.
What is the protein family that this protein belongs to?
Belongs to the PsbZ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein. Note=Associated with the photosystem II complex.
Protein: NSMA_HUMAN
Sequence: MKPNFSLRLRIFNLNCWGIPYLSKHRADRMRRLGDFLNQESFDLALLEEVWSEQDFQYLRQKLSPTYPAAHHFRSGIIGSGLCVFSKHPIQELTQHIYTLNGYPYMIHHGDWFSGKAVGLLVLHLSGMVLNAYVTHLHAEYNRQKDIYLAHRVAQAWELAQFIHHTSKKADVVLLCGDLNMHPEDLGCCLLKEWTGLHDAYLETRDFKGSEEGNTMVPKNCYVSQQELKPFPFGVRIDYVLYKAVSGFYISCKSFETTTGFDPHRGTPLSDHEALMATLFVRHSPPQQNPSSTHGPAERSPLMCVLKEAWTELGLGMAQARWWATFASYVIGLGLLLLALLCVLAAGGGAGEAAILLWTPSVGLVLWAGAFYLFHVQEVNGLYRAQAELQHVLGRAREAQDLGPEPQPALLLGQQEGDRTKEQ
What is the function of this protein?
Catalyzes, at least in vitro, the hydrolysis of sphingomyelin to form ceramide and phosphocholine (PubMed:10608884).  Also hydrolyzes 1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine (lyso-platelet-activating factor) in vivo (PubMed:10608884).  Also acts on 1-acyl-2-lyso-sn-glycero-3-phosphocholine (lyso-PC) and sphingosylphosphocholine (PubMed:10608884, PubMed:14741383).
What are the official names of this protein?
Sphingomyelin phosphodiesterase 2, Lyso-platelet-activating factor-phospholipase C, Lyso-PAF-PLC, Neutral sphingomyelinase, N-SMase, nSMase, nSMase1.
What is the protein family that this protein belongs to?
Belongs to the neutral sphingomyelinase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS15_METFK
Sequence: MAITVQETAKIVADFQQAPNDTGSPEVQVALLSARITYLTEHFKSHAKDHHSRRGLLKLVSQRRKLLDYLKRKNADRYRTLIERLGLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: TOM2A_ARATH
Sequence: MACRGCLECLLKLLNFLLAVAGLGMIGYGIYLFVEYKRVTDNSVTFDLTNGDQSYVSFGRPILMAVSLSSNIFDNLPKAWFIYLFIGIGVALFVISCCGCVGTCSRSVCCLSCYSLLLILLILVELGFAAFIFFDNSWRDELPSDRTGNFDTIYNFLRENWKIVRWVALGAVVFEALLFLLALMVRAANTPAEYDSDDEYLAPRQQIRQPFINRQAAPVTGVPVAPTLDQRPSRSDPWSARMREKYGLDTSEFTYNPSESHRFQQMPAQPNEEKGRCTIM
What is the function of this protein?
Necessary for the efficient intracellular multiplication of tobamoviruses, being a component of the replication complex.
What are the official names of this protein?
Tobamovirus multiplication protein 2A, AtTOM2A.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: Y1070_HELPY
Sequence: MLAYKQIFDKGLKPYYKHSVCLKLFFRFCFLKTHAYQQRYQAFALTLFSCKFFNACKIFLLAIGFKIVFIPILEAKLKRVSNAY
What are the official names of this protein?
Uncharacterized protein HP_1070, ORFX.
Protein: FTSP_DICD3
Sequence: MSLSRRQFIQASGIALCAGAMPLTARADGGKNPLPVPPLLESRRGQPVFLTMQRAHWSFSGERKNPVWGFNGRYLGPTVRVFSNDDVKLIYSNRLNEPVSMTVSGLQVPGSLMGGAGRMIQPNMDWSPVLPVRQAAATCWYHANTPNRMAPHVYNGLAGLWLVEDSLSKSLPIPNHYGVDDFPLIIQDKRLDNFGAPLYNPPSSGGFMGDTLLVNGARNPYVEVSRGWVRLRLLNASNARRYVMRMSDGRPLHLIANDQGFLPAPMALNQMSLAPGERREVLVDMSQGNEATLTAGESASIMQRLRGLFEPSNILVSSAILTLRPTGLLPLVTNTLPMRLLADNIIDGAVSRTREFRLGDSLPGINGAMWDVNRVDVQTQVGRYERWIVHADQPQPFHVQGAAFLVRSVNGGLTPPEDSGWKDTVWVENDVELLVYFGQFSTPQFPFLYYSHTLEMADRGSIAQLVAQASNG
What is the function of this protein?
Cell division protein that is required for growth during stress conditions.  May be involved in protecting or stabilizing the divisomal assembly under conditions of stress.
What are the official names of this protein?
Cell division protein FtsP.
What is the protein family that this protein belongs to?
Belongs to the FtsP family.
What are the subcellular locations of this protein?
Periplasm. Note=Localizes to the division septum.
Protein: DEF_NEIG1
Sequence: MALLNILQYPDERLHTVAKPVEQVDERIRKLVADMFETMYESRGIGLAATQVDVHERVVVMDLTEDRSEPRVFINPVIVEKDGETTYEEGCLSVPGIYDAVTRAERVKVEALNEKGEKFTLEADGLLAICVQHELDHLMGIVFVERLSQLKQGRIKTKLKKRQKHTI
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: FLAB_HELMU
Sequence: MSFRINTNIAALNAHSIGVQTNRNIAGSLEKLSSGLRINKAADDASGMAIADSLRSQSESLGQAVRNANDAIGMIQIADKAMDEQLKILDTIKAKAIQAAQDGQSQESRRSLQSDIRRLMEELDNIANTTSFNGQQMLSGAFTNKEFQIGAYSNTTVKASIGPTSSDKIGHIRMETASFSGVGMLASAGGNNLTEVALNFKATDGVNSFELENVRISTSAGTGIGALSEVINRFSDKLGIRATYNVMATGTSPVMSGTVRGLVINGVRIGTVNEVRKNDSDGRLINAINSVKNQTGVEASLDITGRINLVSLDGRAISVHADGEASHVFGEGNFTGISGNNHAIVGRLTLIRTDARDIIVSGVNFSHIGLHSAQGVAETTANLRQLRGMFGADIASAAGANANKAQADINRQGIGAGVTSLKGAMIVMDMVDSARTQLDKVRSDMGSVQIQLVSTINNISTTQVNVKAAESQIRDVDFAAESANFSKNNILAQSGSFALAQANAVQQNVLRLLQ
What is the function of this protein?
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.  Important for motility and virulence.
What are the official names of this protein?
Flagellin B, Flagellin N.
What is the protein family that this protein belongs to?
Belongs to the bacterial flagellin family.
What are the subcellular locations of this protein?
Secreted. Bacterial flagellum.
Protein: PURA2_CAPFR
Sequence: MNMSALTFNSTPMITTATATDDRSRILGYNGTHSCSRLSRKKNPSIMACSTTKPLAPVVDHHGVNESGLSRIESLSQVSGVLGCQSGDEGKGKLVDMLARHFDIVARCQGGANAGHTIYNSEGKKFLLHLVPSGILNEGTTCVIGNGVVVHLPGLFKEIDGLESNGVSSQGRILVSDRAHLLFDFHQEIDGLREAELAKSFIGTTKRGIGPCYSSKVIRNGIRVSDLRHMDTFSQKLDLLLSDAAARFPDFKYGGPDMLKEEVERYKKFAERLEPFVTDTVHFINGAISQKKKILVEGSQATMLDIDFGTYPFVTSSSSVAGGICTGLGIAPRVVGDLVGVVKAYTTRVGSGPFPTEITGKVGDFLRSAGQEFGNITGRPRRCGWLDIVAVRYCCQINGFASLNLSKLDLLSDLSKIQLGVTYRLPDGSILNSFPSDLHLLEHIKVKYEVLPGWLSDISSIRKYSDLPKAAREYVERIEELVGVPIHYIGIGPGRDAFLYK
What is the function of this protein?
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
What are the official names of this protein?
Adenylosuccinate synthetase 2, chloroplastic, AMPSase 2, AdSS 2, IMP--aspartate ligase 2.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CM3D_CONRE
Sequence: LCCPPQXCGPDCASPCC
What are the official names of this protein?
Conotoxin reg3d.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MURE_CHLAB
Sequence: MNLKELLHNTKAKIYGKISSVEVRNLTRDSRNVGVGDIFIAKQGKHCDGNDFSHLAVENGAIAVASSIYNPFLPVVQIISSDLPRLEADLAAKYYGHPSQKLCVVGITGTNGKTTVSHLIKLLFDACDKPAGLIGTIEHILGNSRIQDGYTTPESCLLQKYLAKMVKSHLSAAVMEVSSIGLAVNRLANVDFDVGVLTNLTLDHLDFHSSFEEYKQAKLKLFSMLPSSGLAVVNNDLCDAAQFIEATQAQPITYGIEQHADYQASHVRFSPFGTDFDLLYKGETFACYSPLIGQHNIYNVLAAIAVTHQRLRCDLPHLISVIANVGAPRGRLEPIFSGPCPIYIDYAHTPDALDNVCQTLQALLPQDGRLIVVFGCGGDRDQSKRKIMAQVVEKYGFAVVTTDNPRGEDPEKIINEICSGFLKRNFSIEIDRKQAITYALSIASDRDIVLVAGKGHETYQIFKHQTIAFDDKEIVLGVLSSYV
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_CYTH3
Sequence: MIAYIEGKLAHKDPTFVVVDVQGIGYHIRVSLHTFSQLKDLERVKIHTFLHIKEDAHTLFGFADLMEKEMFLHLTSISGIGPGTALVVLSSMNPIELKEAIAREDVKTIQSVKGIGLKTAQRVILELKDKMKKDALLAGSDSKQNFSVSHNSIRSEALTALITLGFTKTVAEKNLDLILKGNSNSFTLEDLIKQALKMS
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: Y4021_BACFR
Sequence: MLILLSCAKTMSDVSKTKTPLTTFPGFRKEAAEVALQMSQFSVEELERLLKVNPKIAVENYRRYQAFHSEGTRELPALLAYTGIVFKRVHPQDFSEEDFCYAQDHLRLTSFCYGVLRPLDMIRPYRLEGDVRLPEPGNRTMFDYWKPILTDRFIADIKKVGGVLCNLASDEMRGLFDWKRVEKEVRVITPEFHVWKNGKLATVVVYTKMSRGEMTRYILKNRIESVEQLKTFAWEGFEFNEQLSDETKYVFTNGKTE
What are the official names of this protein?
UPF0246 protein BF4021.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: PMTK_ARATH
Sequence: MKSGKQSSQPEKGTSRILSLTVLFIAFCGFSFYLGGIFCSERDKIVAKDVTRTTTKAVASPKEPTATPIQIKSVSFPECGSEFQDYTPCTDPKRWKKYGVHRLSFLERHCPPVYEKNECLIPPPDGYKPPIRWPKSREQCWYRNVPYDWINKQKSNQHWLKKEGDKFHFPGGGTMFPRGVSHYVDLMQDLIPEMKDGTVRTAIDTGCGVASWGGDLLDRGILSLSLAPRDNHEAQVQFALERGIPAILGIISTQRLPFPSNAFDMAHCSRCLIPWTEFGGIYLLEIHRIVRPGGFWVLSGPPVNYNRRWRGWNTTMEDQKSDYNKLQSLLTSMCFKKYAQKDDIAVWQKLSDKSCYDKIAKNMEAYPPKCDDSIEPDSAWYTPLRPCVVAPTPKVKKSGLGSIPKWPERLHVAPERIGDVHGGSANSLKHDDGKWKNRVKHYKKVLPALGTDKIRNVMDMNTVYGGFSAALIEDPIWVMNVVSSYSANSLPVVFDRGLIGTYHDWCEAFSTYPRTYDLLHLDSLFTLESHRCEMKYILLEMDRILRPSGYVIIRESSYFMDAITTLAKGIRWSCRREETEYAVKSEKILVCQKKLWFSSNQTS
What are the official names of this protein?
Probable methyltransferase PMT20.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: ATPF_LIMF3
Sequence: MFIIAESNQLYLGDMLFYLVSFLIMAALVWHFAWKPVTQMMQKRADKIANDIDSAAQSREEAQKLAAKRQEELKGSRQEAARIVDNAKQAGESQRAEIIATAQQDAQNLKNQAQKDAEQARQDALRGAKKDIANLSIEIASKLIHKQLNADDQQALIDTYIEGLVKHE
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: THIG_CAMJR
Sequence: MQEKLKNDKLKIGKYEFDSRFILGSGKYSLELIKSAIEEAKAQIITLALRRANTGEIANILDYIPKNITLLPNTSGARNAEEALRIARLSRELGCGELIKIEVISDSRYLLPDNYETIKACELLAKEGFTPLPYMHADLYAARAMRDAGAAAIMPLAAPIGSNKGLCAKEFIQILLNEIDLPIIVDAGIGSPSQACEAMQMGVSAVMVNTAIAEAKDIALMARAFSLAVNAGRAAFLAGLASVSEAKASSPLTGFLRD
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_SALTY
Sequence: MQKRAIYPGTFDPITNGHLDIVTRATQMFDHVILAIAASPSKKPMFTLDERVALAQKATAHLGNVEVVGFSDLMANFARDRQANILIRGLRAVADFEYEMQLAHMNRHLMPQLESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPDNVHQALMDKLK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_WOLSU
Sequence: MIYIDNIVAQEVMDSRGNPTVKATVTLSDGNSASAIVPSGASTGKREALELRDGDSRYLGKGVLQACENVNTKLSEELIGLSPFDQSEIDAIIQELDGTENFANIGANAALGVSMAVARSAAKSLNIPLYRYLGGANALTLPVPMLNIINGGSHADNTVDFQEYMIMPLGFENFSESLRASAEVYHHLKKILKDSKHITSIGDEGGFAPNLKTNEEPIQIIIQAIEKAGYRPGEEIALALDVASSEFVNEQGLYHLEGEGRTLSSEELVGYYESLIAKYPIVSIEDGLSEDDWKGWKYLTERLGGKVQLVGDDLFVTNAKILQEGISQGIANAILIKPNQIGTVSQTMQTVRLAQRNHYRCVMSHRSGESEDSFIADFAVALNTGEIKTGSTARSERIAKYNRLLAIESELCRSEYLGRSLF
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: PROBJ_OLEEU
Sequence: MSWQTYVDDHLMCDIEGHEGHRLTAAAIVGHDGSVWAQSATFPQFKPEEMNGIMTDFNEPGHLAPTGLHLGGTKYMVIQGEAGAVTRGKKGTGGITIKKTGQALVFGIYEEPVTPGQCNMVVGRLGDYLLEQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity).
What are the official names of this protein?
Profilin-2, Pollen allergen Ole e 2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: TATA_ANADF
Sequence: MFPKLGMGELVVILLIVVILFGASKLPQLGAGLGQGIRSFKKSFSGEDEEKPSTPGATSSDEASKAKQA
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.