PharMolix/UniProtQA huggingface dataset:
Protein: DCUP_XYLFT
Sequence: MLKNDRLLRALRRDTVDRTPIWLMRQAGRYLPEYRAARQHAGSFLKMAKTPELACEITLQPLRRFPLDAAILFSDILMIPDAMGLELHFIEGEGPRLGKPIRDAAAITQLAVPDMETELRYVMDAVRLIRKELDNSVPLIGFSGSPWTLACYMIEGGSSKEYARIKAMAFNAPDVLHQLLNTVTDAVISYLAAQRAAGAQALQVFDTWGGILSPTMYRTFSLPYLTRIARELERGTGTEHTPLVLFGKGNGPYIAELAMSGTEAVGVDWTIELEDAARRSNGQVALQGNLDPATLYGTPNNIAREVQRTLDSYAAGNGGSREGHVFNLGHGMTPGMNPDHVSALVEAVQRLSRR
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CXE6_ARATH
Sequence: MGGTKLTHVTTTNPNNSNIHGPVVDEVEGLIKVYKDGHVERSQLLPCVDPSLPLELGVTCSDVVIDKLTNVWARLYVPMTTTKSSVSKLPLIVYFHGGGFCVGSASWLCYHEFLARLSARSRCLVMSVNYRLAPENPLPAAYEDGVNAILWLNKARNDNLWAKQCDFGRIFLAGDSAGGNIAQQVAARLASPEDLALKIEGTILIQPFYSGEERTESERRVGNDKTAVLTLASSDAWWRMSLPRGANREHPYCKPVKMIIKSSTVTRTLVCVAEMDLLMDSNMEMCDGNEDVIKRVLHKGVGHAFHILGKSQLAHTTTLEMLCQIDAFIHHYDPLN
What is the function of this protein?
Carboxylesterase acting on esters with varying acyl chain length.
What are the official names of this protein?
Probable carboxylesterase 6, AtCXE6.
What is the protein family that this protein belongs to?
Belongs to the 'GDXG' lipolytic enzyme family.
Protein: RL36_RHOE4
Sequence: MKVQPSVKKICEKCKVIRRNGRVMVICENLRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: EFG_PROM1
Sequence: MARAFPLERVRNIGIAAHIDAGKTTCTERILFYSGVVHKMGEVHDGAAVTDWMAQERERGITITAAAISTTWDDHRINIIDTPGHVDFTIEVERSMRVLDGVIAVFCAVGGVQPQSETVWRQADRYSVPRMVFVNKMDRTGADFLKVHGQIKDRLKANAVPIQLPIGAENDLKGIIDLVENKAYIYKDDLGKDIEQTEVPSDMVDLVSDWRLKLMESIAETEEELLEAFLENGELTIEQLKSGIREGVLKHGLVPMLCGSAFKNKGVQLLLDAVVNYLPAPVDVPPIQGLLPNGKEAVRPSDDGAPFSALAFKVMADPYGKLTFVRMYSGVLEKGSYVLNSTKDAKERISRLIILKADDREEVDELRAGDLGAVLGLKNTTTGDTLCASEEAIVLETLYIPEPVISVAVEPKTKSDMEKLGKALTSLSEEDPTFRVSTDQETNQTVIAGMGELHLEILVDRMLREFKVEANIGAPQVSYRETIRASSSGEGKFARQTGGKGQYGHVVIEVEPGEPGTGFEFVNKIVGGSVPKEYIKPAESGMRETCESGVIAGYPLIDVKVTLVDGSYHDVDSSEMAFKIAGSMAFKDGIKKCNPVLLEPMMKVEVEVPEDFLGSIIGDLSSRRGQVEGQSIEDGQSKVQSKVPLAEMFGYATQLRSMTQGRGIFSMEFSTYEEVPRNVAEAIISKNQGNS
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSH_YERPG
Sequence: MSNVPTELKYALSHEWVRADGDGVYSVGITEHAQELLGDMVFVDLPEVGSDVSAGSDCAVAESVKAASDIYAPISGEIVAVNTELENSPELVNSAPYTDGWLFSIKAADESELDNLLDADAYLAAIEE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: RL22_SULAC
Sequence: MSKWVYPILSIPEDKLAKAVIKNIDASVRDLYNVCKAIRGMNLKEAREFLNNVLEEKEALPFWRYSHGTSHRSNISRKWKVKSGRYPKKAIKYVLKLLDNAENNANSKGLDIDNLKIVHIAAHKGLVLKRYMTRAFGRSTRKYKYLSHIEVILGEV
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RL34_POLSJ
Sequence: MKRTYQPSKVKRARTHGFLTRMKTRGGRAVIAARRAKGRKRLAV
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: SPP2_TOBAC
Sequence: MDQLTSAARLMIVSDLDHTMVDHHDAENLSLLRFNALWEANYRDNSLLVFSTGRSPTLYKELRKEKPMLTPDITIMSVGTEITYGNSVVPDDGWEAFLNNKWDRKIVTEETSKFPELTLQSETEQRPHKVSFYVQKDKAQDIMKTLSKRFEERGLDVKIIYSGGMDLDILPQGAGKGQALAYLLKKLKSEGKLPNNTLACGDSGNDAELFSIPDVYGVMVANAQEELLQWHAANAKNNPKVIHATERCAAGIIQAIGHSNLGPSTSPRDVMDLSDCKMENFVPAYEVVKFYLFFEKWRRGEIEHSEHYLSNLKAVCRPSGTFVHPSGVEKSLQECVTLFGTCHGDKQGKQFRIWVDQVLPVQVGSDSWLVSFKKWELSGEDRRCCITTVLLSSKNKTVADGLTWTHVHQTWLNGAAASDSASWFF
What is the function of this protein?
Catalyzes the final step of sucrose synthesis.
What are the official names of this protein?
Sucrose-phosphatase 2, NtSPP2.
What is the protein family that this protein belongs to?
Belongs to the sucrose phosphatase family.
Protein: RS15_THEYD
Sequence: MGISPERKKEIIESFKMHSSDTGSPEVQIALMTERINYLTEHFKTHKKDHHSRRGLIKLVAQRRKLLNYLKKIDKERYGKLIERLSIRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: ARRD1_MOUSE
Sequence: MGRVQLFEIRLSQGRVVYGPGEPLAGTVHLRLGAPLPFRAIRVTCMGSCGVSTKANDGAWVVEESYFNSSLSLADKGSLPAGEHNFPFQFLLPATAPTSFEGPFGKIVHQVRASIDTPRFSKDHKCSLVFYILSPLNLNSIPDIEQPNVASTTKKFSYKLVKTGNVVLTASTDLRGYVVGQVLRLQADIENQSGKDTSPVVASLLQKVSYKAKRWIYDVRTIAEVEGTGVKAWRRAQWQEQILVPALPQSALPGCSLIHIDYYLQVSMKAPEATVTLPLFVGNIAVNQTPLSPCPGRESSPGTLSLVVPSAPPQEEAEAVASGPHFSDPVSLSTKSHSQQQPLSAPLGSVSVTTTEPWVQVGSPARHSLHPPLCISIGATVPYFAEGSAGPVPTTSALILPPEYSSWGYPYEAPPSYEQSCGAAGTDLGLIPGS
What is the function of this protein?
Functions as an adapter recruiting ubiquitin-protein ligases to their specific substrates (PubMed:23886940, PubMed:27462458).  Through an ubiquitination-dependent mechanism plays for instance a role in the incorporation of SLC11A2 into extracellular vesicles (PubMed:27462458).  More generally, plays a role in the extracellular transport of proteins between cells through the release in the extracellular space of microvesicles (By similarity).  By participating to the ITCH-mediated ubiquitination and subsequent degradation of NOTCH1, negatively regulates the NOTCH signaling pathway (PubMed:23886940).
What are the official names of this protein?
Arrestin domain-containing protein 1, Alpha-arrestin 1.
What is the protein family that this protein belongs to?
Belongs to the arrestin family.
What are the subcellular locations of this protein?
Cell membrane. Note=Also found in extracellular vesicles different from exosomes.
Protein: METK_ECODH
Sequence: MAKHLFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGMVLVGGEITTSAWVDIEEITRNTVREIGYVHSDMGFDANSCAVLSAIGKQSPDINQGVDRADPLEQGAGDQGLMFGYATNETDVLMPAPITYAHRLVQRQAEVRKNGTLPWLRPDAKSQVTFQYDDGKIVGIDAVVLSTQHSEEIDQKSLQEAVMEEIIKPILPAEWLTSATKFFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVSYAIGVAEPTSIMVETFGTEKVPSEQLTLLVREFFDLRPYGLIQMLDLLHPIYKETAAYGHFGREHFPWEKTDKAQLLRDAAGLK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUN3B_MOUSE
Sequence: MASRSLGGLSGSRGGGGGGGGKKSLSARNAAVERRNLITVCRFSVKTLIDRSCFETIDDSSPEFNNFAAVLEQILSHRLKGQVTWFGYESPRSFWDYIRVACRKVSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVLGEEANMLAGMLLGLNAIDFSFCLKGEGLDGTFPAVIDYTPYLKFEQSSDSISSDEEELRTFGSSDSESSTPENVGPPLILDENTWFNKCKRVRQKYQLTLEQKGYLEELLRLRENQLSESVSQNKILLQRIEDSDLAHKLEKEQLEYIIVELQDQLKSYQSLDQLSAEVSLSQASLDPSHSQEGDGKQDSLNFIGEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDCLASPTTELTSPGLTPS
What are the official names of this protein?
RUN domain-containing protein 3B.
What is the protein family that this protein belongs to?
Belongs to the RUNDC3 family.
Protein: RL32_THESM
Sequence: MNEKVRLLKIRAKIKRKKPKFLRQEWWRFPKFKNDPKWRKPKGTDSKMRVKLKGKARSPSIGWSSPKAVRGLHPSGYEEVLVYNVKDLELIDSKRQAARIAATVGKKKRIMIIERARELGIKVLNAR
What are the official names of this protein?
50S ribosomal protein L32e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL32 family.
Protein: METN_STRA3
Sequence: MSKEPIIKLDNIDVTFHQKKREINAVKDVTIHINQGDIYGIVGYSGAGKSTLVRVINLLQEPSAGKITIDNQVIYDNKVTLTSTQLREQRREIGMIFQHFNLMSQLTAEQNVAFALKHSGLSKEAKAAKVAKLLELVGLSDRAQNYPSQLSGGQKQRVAIARALANDPKILISDESTSALDPKTTKQILALLQDLNKKLGLTIVLITHEMQIVKDIANRVAVMQNGKLIEEGSVLDIFSHPRESLTQDFIKIATGIDEAMLKIEQQEVVKNLPVGSKLVQLKYAGHSTDEPLLNQIYKEFEVTANILYGNIEILDGIPVGEMVVILSGDEEKLRQACQAITDSQVQLTLLKEGGKA
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: KAD_HYDCU
Sequence: MKFILLGAPGAGKGTQAQFLTKEFNIPQISTGDMLRAAIKAQTPMGKMAKEFMDAGKLVTDEIIIGLVKDRIAEPDCANGFLLDGFPRTVPQADALKAAGVEIDAVIEIDVPDSEIVNRMAGRRVHPASGRTYHITYNPPKVDDKDNETGDDLIQREDDKAEVVLDRLKVYHEQTAPLIGYYKAEAEKNDQLKYIQVDGTQPIDTVEKSILSALK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GMHA_VIBPA
Sequence: MYQDLIRSELNEAAEVLNKFLSDDHNIAQIEAAAKMIADSFKQDGKVLSCGNGGSHCDAMHFAEELTGRYRDNRPGYAGIAISDPSHLSCVSNDFGYDFVFSRYVEAVGRKGDVLFGLSTSGNSGNILKAIEAAKAKGMKTVALTGKDGGKMAGLADVEIRVPHFGYADRIQEVHIKIIHIIIQLIEKEME
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_THEP3
Sequence: MEYSHKSVLLKETIEYLNIKPEGIYVDGTLGGGGHSEEILKRLTTGKLIAIDRDLDAIKASKERLKNYKNAEYINDNFKNIKEILKSLNIDKVDGILLDLGVSSYQLEEVKRGFSYMKDAPMDMRMDKNSPFSAYDVVNKYSQQELERVIREYGEEKWASRIAKFIVKEREKGEIKTTFQLVEIIKNAVPASARREGPHPAKRTFQAIRIEVNEELKGLDKAIEDMVEVLRGKGRIAIITFHSLEDRIVKNTFKKLENPCTCPPNMPCTCGKKPVVKIITKKPVLPSKEEIETNSRSRSAKLRVAEKL
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBRG_RAT
Sequence: MAGVKALVALSFSGAIGLTFLMLGCALEDYGVYWPLFVLIFYVISPIPYFIAKRVTYDSDATSSACRELAYFFTTGIVVSAFGFPVILARVAVIKWGACGLVLAGNAVIFLTIQGFFLVFGRGDDFSWEQW
What is the function of this protein?
Negatively regulates leptin receptor (LEPR) cell surface expression, and thus decreases response to leptin (By similarity).  Negatively regulates growth hormone (GH) receptor cell surface expression in liver.  May play a role in liver resistance to GH during periods of reduced nutrient availability.
What are the official names of this protein?
Leptin receptor gene-related protein, Endospanin-1, OB-R gene-related protein, OB-RGRP.
What is the protein family that this protein belongs to?
Belongs to the OB-RGRP/VPS55 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein. Endosome membrane.
Protein: ATPD_NEIG2
Sequence: MAEFATIARPYAKALFGLAQEKNQIESWLGGLEKLAAVVQEGKVALLIDRPETNASEKADILIDLVGLKDKELKNFVIVLAGQKRLSILPEVYAQYQDLTLSFNHIKSAVIYSAYPLTDKQVGELAQMLNKRFDSELKISVEIEPELIGGIKVEVGDQVLDLSVQGKLSALYTTMTN
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RF1_THEPX
Sequence: MIDKLQAIEDRYVELSQKISDPNIISNVNEWRKYVKEHAAIEDIVLKYREYKKVLEDIEATKELLSSNDEELKEMAEEELSQLEEKKEKLLEEIKILLIPKDPNDEKNVIMEIRAGAGGEEAALFAHDLFRMYSMYAEKKGWKVEIMSSNETDIGGFKEVILNISGKGSYSRLKYESGVHRVQRVPTTEAGGRIHTSTATVAVLPEVEEVDVEINPNDIKVDVFRSGGHGGQSVNTTDSAVRVTHIPTGIVVTCQDERSQIQNRERALKILRAKLYEMALQEQQREIAETRKSQVGTGERSERIRTYNYPQGRVTDHRIGLTLYRLQEVLDGDLDEIIDALILNDQAEKLKNMNLN
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NHAA_GEOSL
Sequence: MRKRINLLREFSVPLIAGVVVALLWANLDPAGYHSFIEQPFFGGMSFHFVVNELFMVLFFGIAAVEITQSCLPGGDLNPLRKAVNPLLATLGGVVGPVLVYLGLNAIIGGPELTRGWGIPTATDIALAWLVARLVFGAGHPAVSFLLLLAVADDAIGLAIIAVFYPDPNHPTEPIWLFLTVAGMVVAYILRSLKSRSYWPYVVVGGGLAWTGLFKAHLHPALALVFIIPFLPHPSRETAHLFEADPRDTSTLARFEHDWKIVVDFGLFMFGLANAGVGFSSVGAATWLVLASLVIGKTLGIFAMGYVGRALGFPLPQQVGAKELAMTGLVAGIGLTVALFVAGVAFVEPDIQGSAKMGALLSGGVSIVAIMLGRALNVRRIP
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EFP_EHRRG
Sequence: MAERGSDIRPGYVLEHNNALYLVVKIMHTQPGKGGAYIQAEMKNLKTGAKQYERFRADGDIKRAILDEADYQYIYGDDSMLTVMHLGNYEQITIKKDILGDKSIYLKDNMVITLLSYNGEIISAKVPDYVTLQVIETEAVIKGQTVSSSSYKVAMLENNQRINVPTFIKSGDKIVVYTPDDSYYERAKE
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCX2_ANDAM
Sequence: MNYLITISLALLLMTGVASGVRDGYIADAGNCGYTCVANDYCNTECTKNGAESGYCQWFGRYGNACWCIKLPDKVPIKVPGKCNGR
What is the function of this protein?
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission.
What are the official names of this protein?
Toxin Aam2, AamH2, Alpha-neurotoxin 2.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RIO1_SCHPO
Sequence: MVEELKNDAQTNEEESEYSDFSDGSDNDYFREDDIDWNQASSNYSARQENFGNNSSKINSVNDHVSTLSRYVNNIKLNDRFEAEDKSSIKDKSDRATSEQVLDPRTRMILLKLINNGTISEINGCISTGKEANVYHATNEDGKHFAIKIYKTSILVFKDRDRYVSGEFRFRHGYNKRNPRKMVRLWAEKEIRNLKRVAAAGIPCPEPILLKQHVLLMSFLGDKKGWAYPKLKDIDMTPGEATKLYQLVARNMRILFHVCHLVHADLSEYNLLYHKGKVYFIDVSQSVEHDHPQSIDFLRMDILNISTFFRRLNAGCLSLPQLFKFITEEGSCEKEAMKTRLNAIYEEEPTTEEYEEEFLKTYVPRTLDEVYDIDRDTEIVNAGGVNSLVYKHLLNTDFQKLDLNDTTKNQNDQILPNETSESDDDANSISSMENEEERTSDSKSSAKQGKGNGRAKETPEEKRARKKKTKEDKAEKRKSKIPKYEKKRKLKQSGRKK
What is the function of this protein?
Required for the final endonucleolytic cleavage at site D converting 20S pre-rRNA into the mature 18S rRNA.  Required for the final steps of cytoplasmic maturation of the 40S ribosomal subunit.  Despite the protein kinase domain is proposed to act predominantly as an ATPase (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase rio1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_PORG3
Sequence: MAHPKRRQSKTRTAKRRTHDKAVMPTLAKCPNCGAWHIYHTVCGDCGYYRGKLAIEKEVAV
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: BTLA_RAT
Sequence: MKTVPAMLVTPRSFREFFILLLGLWSILCKEPTKRIGEECRVQLKIKRNSSRSAWTGELFKIECPVTYCVHRPNVTWCKHNGTRCVPLEVGPQLHTSWVENDQASAFVLYFEPIHLSDDGVYTCSANLNSEVINSHSVVIHVTERTQNCSEHPLITASDIPDATNASRPSTMEERPGRTWLLYALLPLGTSLLLLACVCLLCFLRRIQGKEKKPSDLAGRERETNLVDIPVSSRTNSQILTSETGIYDNDPWSSRLGESESTISSQLEGNKQGIVYASLNHCVIGRTPRQASKIQEAPTEYASICVRS
What is the function of this protein?
Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2.  May interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14.  In cis interactions, appears to play an immune regulatory role inhibiting in trans interactions in naive T cells to maintain a resting state.  In trans interactions, can predominate during adaptive immune response to provide survival signals to effector T cells.
What are the official names of this protein?
B- and T-lymphocyte attenuator, B- and T-lymphocyte-associated protein.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: GATB_THESQ
Sequence: MRYRPVIGLEIHVQLSTKTKAFCSCPADVFELPPNTAICPVCTGQPGALPVPNEEMIRFAVKTALALNCKIHKYSRFDRKNYFYPDLPKGYQISQYFYPIATEGFLEIDGDEGKKKVRIRRLHLEEDAGKLVHEGDSITRASYSLVDMNRCGVPLIEIVTEPDISSPREARVFMEKLRSIVRYLGVSTGDMEKGALRCDANISVVDTETGRQSNRVEVKNMNSFRFVEKALEYEFERIVKAMERGEDVERETRGWDMTTKTTVSMRGKEEESDYRYFPEPDIPPVVLSDEYLEEVKKELPELPDEKAKRFMREYDLPEYDAKVLTSSKELAEFFEECVKVVNRPKDLSNWIMTEVLRELNERNIEITESKLTPQHFADLFKLMDEGKISIKIAKEIFPEVFETGKMPSQIVEEKGLVQISDEKLIEELVKKAMEQNPKAVQDYKSGKKKAAGFFVGYVMRETKGKANPELTNRIIQKLLEGE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: THIC_BACLD
Sequence: MKQESVQQKNISIMSSFSGSRKVYVEGSRPDIQVPMREISLSPTTGSFGDEENQPVRVYDTSGPYTDANADVDILKGLKPLRATWIRERGDTEEYEGREIRPEDNGYKGKEKASHSYTGLKRKPLRAKKGQNVTQLHYARKGIITPEMEFIAIREHVSPEFVRDEVASGRAIIPSNINHPESEPMIIGRNFHVKINANIGNSAVTSSIEEEVEKMTWAIRWGADTMMDLSTGKDIHTTREWIIRNCPVPVGTVPIYQALEKVNGVAEDLTWDIYRDTLIEQAEQGVDYFTIHAGVLLRYVPLTAKRVTGIVSRGGAIMAQWCLAHHEESFLYTHFEEICEIMKTYDIAFSLGDGLRPGSIADANDEAQFAELETLGELTEIAWKHDVQVMIEGPGHVPMHKIKENVDKQMEICKEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWYGTAMLCYVTPKEHLGLPNKDDVREGVITYKIAAHAADLAKGHPGAQIRDDALSKARFEFRWRDQFNLSLDPERALEYHDETLPAEGAKTAHFCSMCGPKFCSMRISQDIRDYAKENNLDEEKAIQKGLEEKAKEFKKAGGSIYS
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: TR5OS_MOUSE
Sequence: MESVSIPVLVAGLIDCVAQLIRIAEDLLQFISQEQVPSVQQNARAEEAEAAAPPAEEDSLPDLADLSDLESILSVREDDDLILDTDETMIDINEIYKDILPAIKDDTESE
What are the official names of this protein?
Putative uncharacterized protein TRPC5OS homolog.
Protein: NU6C_CITSI
Sequence: MDLPGPIHDFILVFLGSGLILGGLGVVLFTNPIYSAFSLGLVLVCISLFYILSNSHFVAAAQLLIYVGAVNVLIIFAVMFMNGSDYSKDFQLNLWTIGDGLTSLVCTSIFFSLITTILDTSWYGIIWTTRANQIIEQDLISNSQQIGIHLSTDFFLPFELVSIILLVALIGAIAVARQ
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 6, chloroplastic, NAD(P)H dehydrogenase subunit 6, NADH-plastoquinone oxidoreductase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: CRCB1_GEOKA
Sequence: MYAPLFVAIGGFFGAMARYLVSRWAARRSPRFPLGTLIVNLLGSFLLGWLAGSGAADAAKLLVGTGFMGAFTTFSTLKWESVQMMQQRQWAKVVVYLAATYLCGVWLAWLGYHVGR
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 1.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.