PharMolix/UniProtQA huggingface dataset:
Protein: SELS_MOUSE
Sequence: MDRDEEPLSARPALETESLRFLHVTVGSLLASYGWYILFSCILLYIVIQRLSLRLRALRQRQLDQAETVLEPDVVVKRQEALAAARLRMQEDLNAQVEKHKEKLRQLEEEKRRQKIEMWDSMQEGRSYKRNSGRPQEEDGPGPSTSSVIPKGKSDKKPLRGGGYNPLTGEGGGTCSWRPGRRGPSSGGUN
What is the function of this protein?
Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins.  Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner.  Probably acts by serving as a linker between DERL1, which mediates the retrotranslocation of misfolded proteins into the cytosol, and the ATPase complex VCP, which mediates the translocation and ubiquitination (By similarity).
What are the official names of this protein?
Selenoprotein S, SelS, Minor histocompatibility antigen H47.
What is the protein family that this protein belongs to?
Belongs to the selenoprotein S family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Cytoplasm.
Protein: SLB_TROWA
Sequence: ELCCPMERSS
What is the function of this protein?
Potently induces platelet aggregation of washed human platelet and platelet-rich plasma in a concentration-dependent manner.  It acts by binding to GPVI (GP6), leading to kinases-dependent exposure of functional alpha-IIb/beta-3 and platelet aggregation, and also induces metalloproteinase-dependent GP6 shedding from platelets.
What are the official names of this protein?
Snaclec trowaglerix subunit beta.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: DAPE_PSYIN
Sequence: MSDSPVLALLKDLISRRSITPSDEGCQQLLISRLEKLGFECEVMIFADTTNLWARRGTEKPLFCFAGHTDVVPTGPEENWTYPPFEPTVVDGFLFGRGAADMKSGIAAFIIALEQFIKAHQDHQGSIALLITSDEEGPFINGTVRVIETLEARNEKIDYCIVGEPSSTEHVGDTIKNGRRGSLTADLTINGVQGHVAYPHMVENPIHTCIGPLTELSQMEWDKGNKYFPPTSFQVTNFNAGTGASNVVPGEAQIQFNFRYSTELTAEMIIARVVAILQKHKLNYQIKWTYNGSPFITQPGSLTNAVSEAIFAVNGLTTELSTSGGTSDARFIAPTGAQVVELGPGNKTIHKVNESVKIADLEELVHIHRLTLEKLLT
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: RNPH_ECO5E
Sequence: MRPAGRSNNQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTASIEEGVPRFLKGQGQGWITAEYGMLPRSTHTRNAREAAKGKQGGRTMEIQRLIARALRAAVDLKALGEFTITLDCDVLQADGGTRTASITGACVALADALQKLVENGKLKTNPMKGMVAAVSVGIVNGEAVCDLEYVEDSAAETDMNVVMTEDGRIIEVQGTAEGEPFTHEELLTLLALARGGIESIVATQKAALAN
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: DPH3_YARLI
Sequence: MSFYDEIEIEDMIFDADQGILTYPCPCGDKFQIALDDLKDGEEVAVCPSCSLMIKVIFDPEDLEQFEES
What is the function of this protein?
Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2.  DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising KTI11/DPH3 and a NADH-dependent reductase, predominantly CBR1.  Acts as an electron donor to reduce the Fe-S cluster in DPH1-DPH2 keeping the [4Fe-4S] clusters in the active and reduced state.  Restores iron to DPH1-DPH2 iron-sulfur clusters which have degraded from [4Fe-4S] to [3Fe-4S] by donating an iron atom to reform [4Fe-4S] clusters, in a manner dependent on the presence of elongation factor 2 and SAM.  Associates with the elongator complex and is required for tRNA Wobble base modifications mediated by the elongator complex.  The elongator complex is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s 2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine).
What are the official names of this protein?
Diphthamide biosynthesis protein 3.
What is the protein family that this protein belongs to?
Belongs to the DPH3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RIE1_ARATH
Sequence: MSSYSSDSTAARDQHAPLLRPRHDGSFSSSSSSARPTALAVLLGRITGHRAPSMLVRETAARALEERRIDWGYSKPVVAADILWNAALVLASAVMLVGTVEERPNEPIRVWICVYGLQCLFHVVLVWSEYWRRNSTRRARDLESYDHEDYNIEYDYEQDSDDNSTTYSFVKRCESINTVISFIWWIIGFYWVVEGGDKLLGEAPNLYWLSVIFLAIDVFFAVFCVVLACLVGIALCCCLPCIIALLYAVAGTEGVSEAELGVLPLYKFKAFHSNEKNITGPGKMVPIPINGLCLATERTLLAEDADCCICLSSYEDGAELHALPCNHHFHSTCIVKWLKMRATCPLCKYNILKGTTDQS
What is the function of this protein?
Probable E3 ubiquitin-protein ligase required for embryo development.
What are the official names of this protein?
E3 ubiquitin protein ligase RIE1, Protein RING-FINGER FOR EMBRYOGENESIS 1, RING-type E3 ubiquitin transferase RIE1.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ITA6_CHICK
Sequence: MAAALLLYLPLLPGLAGAFNLDAENVIGRRGEPGSLFGFSLAMHRQLQPQEKRLLLVGAPREKAFPSQQANRTGGLYSCDITSSDTRCTRVVFDEDTDPKMESKEDQWMGVTVQSQGPGGNVVTCAHRYEKRQYVNTVQETRDIIGRCYVLSQDLTIKDDMDNGVWSFCDGRLRGHEKFGSCQQGVAATFTRDYHYIVFGAPGTYNWKGVVRAEQKNQTFYDLGIFDDGPYEVGDESRQDKNLVPVPANSYLGFSLDSGKGIVSQDEMTFVSGAPRANHSGAVVLLKKEKNQRALSLEHMFEGEGLASSFGYDVAVVDLNSDGWQDIVVGAPQYFDRSGDIGGAVYIYINQRGKWEGIKPIRLNGTADSMFGLAVENVGDINQDGYPDIAVGAPYDGFGKVYIYHGSKNGINTEPAQILDGEKTGTNFFGYSIAGNMDLDKNSYPDIAVGSLSDSVSVFRSRPVISITKSITVQPDKLDLKKKNPEDPSEIWMDVKACFQYTANPRNLNPRIKINYTFEAENERRQLGLPSRVRFKDYLSDQFTASTTLIGQNSKRCVTAKLVLQEKIKDKLRPIPIAVSVNIAGLESGSSSTRKERALPDLIPILNSNESETKITKVEFLKEGCGEDNECHSNLKLQYRFCTREGNEDRFTYLPIENGIPVLVLKDQKDIALEITVTNNPSDARNPQKDGEDAYEAKLIATFPDSLTYSAFREMRGYPEKQLTCGANQNGSQAECELGNPFKRNSNVTFYLILSTTKVNVDTTDLDINLKLETTSTQVNSTAITASAKVVLELLLSLTGVAKPSQVYFGGNIVGESAMKSEDNIGNLIEYEFRVTNLGRPLKTFGTASLDIQWPKEISNGKWLLYLMKIESKGLEKVSCQPQNEINVLHVAESHNSRRKREIAEKQLTDSKTFSLFSERKYKTLDCKVNAQCVDIRCPLKGFDSKASILLRSRLWNSTFLEEFSKMNYLDILVRASISVPAAAKNVKLTNEAAQVRVTVFPAKPVALYTGVPWWIIAVAIFAGVLMLALLVFLLWKCGFFKRSKKDHYDATYHKAEIHAQPSDKERLTSDA
What is the function of this protein?
Integrin alpha-6/beta-1 (ITGA6:ITGB1) is a receptor for laminin on platelets.  Integrin alpha-6/beta-1 (ITGA6:ITGB1) is present in oocytes and is involved in sperm-egg fusion.  Integrin alpha-6/beta-4 (ITGA6:ITGB4) is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome.
What are the official names of this protein?
Integrin alpha-6, VLA-6.
What is the protein family that this protein belongs to?
Belongs to the integrin alpha chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell membrane; Lipid-anchor.
Protein: VATD_METM6
Sequence: MADVNPTRMELLKLKGKIKLAEKGHKLLKQKRDALMMEFFEILDQASGIRDKVNDAISQAYKDLIMAQAVMGTLSVKEASFAAKNDNIDLDVDMRNIMGIDVPVFEISNVKRDISNRGYSPYGVSSKLDEAAKNFEEALELITELAEIETSIKLLAQEIITTKRRVNALEYVVIPKMNATKKYIAMRLEEMERENFFRLKIIKARMDAKEAEEA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit D, V-ATPase subunit D.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase D subunit family.
Protein: OPRM_HUMAN
Sequence: MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
What is the function of this protein?
Does not bind agonists but may act through oligomerization with binding-competent OPRM1 isoforms and reduce their ligand binding activity.
What are the official names of this protein?
Mu-type opioid receptor, M-OR-1, MOR-1, Mu opiate receptor, Mu opioid receptor, MOP, hMOP.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell projection, axon. Perikaryon. Cell projection, dendrite. Endosome. Note=Is rapidly internalized after agonist binding. SUBCELLULAR LOCATION: [Isoform 12]: Cytoplasm.
Protein: SYFA_STRP3
Sequence: MDLQAQLEELKTKTLETLQSLTGNHTKELQDLRVAVLGKKGSLTELLKGLKDLSNDLRPVVGKQVNEVRDLLTKAFEEQAKIVEAAKIQAQLDAESIDVTLPGRQMTLGHRHVLTQTSEEIEDIFLGMGFQIVDGFEVEKDYYNFERMNLPKDHPARDMQDTFYITEEILLRTHTSPVQARTLDQHDFSKGPLKMVSPGRVFRRDTDDATHSHQFHQIEGLVVGKNISMGDLKGTLEMIIKKMFGEERSIRLRPSYFPFTEPSVEVDVSCFKCGGKGCNVCKKTGWIEILGAGMVHPSVLEMSGVDAKEYSGFAFGLGQERIAMLRYGINDIRGFYQGDQRFSEQFN
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA1_NEIMB
Sequence: MPTMGAEMNTRNMRYILLTGLLPMASAFGETALQCAALTDNVTRLACYDRIFAAQLPSSAGQEGQESKAVLNLTETVRSSLDKGEAVIVVEKGGDALPADSAGETADIYTPLSLMYDLDKNDLRGLLGVREHNPMYLMPLWYNNSPNYAPGSPTRGTTVQEKFGQQKRAETKLQVSFKSKIAEDLFKTRADLWFGYTQRSDWQIYNQGRKSAPFRNTDYKPEIFLTQPVKADLPFGGRLRMLGAGFVHQSNGQSRPESRSWNRIYAMAGMEWGKLTVIPRVWVRAFDQSGDKNDNPDIADYMGYGDVKLQYRLNDRQNVYSVLRYNPKTGYGAIEAAYTFPIKGKLKGVVRGFHGYGESLIDYNHKQNGIGIGLMFNDLDGI
What is the function of this protein?
Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3. 1. 1. 4) and phospholipase A1 (EC 3. 1. 1. 32) activities.
What are the official names of this protein?
Putative phospholipase A1, Phosphatidylcholine 1-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A1 family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein. Note=One of the very few enzymes located there.
Protein: RFA1_XENLA
Sequence: MALPQLSEGAISAMLGGDSSCKPTLQVINIRPINTGNGPPRYRLLMSDGLNTLSSFMLATQLNSLVDNNLLATNCICQVSRFIVNNLKDGRRVIIVMELDVLKSADLVMGKIGNPQPYNDGQPQPAAPAPASAPAPAPSKLQNNSAPPPSMNRGTSKLFGGGSLLNTPGGSQSKVVPIASLNPYQSKWTVRARVTNKGQIRTWSNSRGEGKLFSIEMVDESGEIRATAFNEQADKFFSIIEVNKVYYFSKGTLKIANKQYTSVKNDYEMTFNSETSVIPCDDSADVPMVQFEFVSIGELESKNKDTVLDIIGVCKNVEEVTKVTIKSNNREVSKRSIHLMDSSGKVVSTTLWGEDADKFDGSRQPVVAIKGARLSDFGGRSLSVLSSSTVMINPDIPEAFKLRAWFDSEGQVVEGTSISESRGGGTGGGNTNWKSLLEVKNENLGHGEKADYFTSVATIVYLRKENCLYQACPSQDCNKKVIDQQNGLFRCEKCNKEFPNFKYRLILSANIADFGENQWITCFQESAESILGQNATYLGELKEKNEQAYDEVFQNANFRSYTFRARVKLETYNDESRIKATAVDVKPVDHKEYSRRLIMNIRKMATQGV
What is the function of this protein?
As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress.  It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism.  Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
What are the official names of this protein?
Replication protein A 70 kDa DNA-binding subunit, RP-A p70, Replication factor A protein 1, RF-A protein 1, Single-stranded DNA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the replication factor A protein 1 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, PML body.
Protein: CRCB_HYPNA
Sequence: MNGFLLVALGGAIGASLRHGVGLVAVRHLPLGWPWGTSFVNIAGSLAMGLLAGWLALKAEGASQEARLFLATGVLGGFTTFSAFSLEVATMLRSGETLKAGLYAGVSVLLGVSALFIGLWMARRIFA
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSBZ_NEOYE
Sequence: MIIAIQLLVLLLIALSTVLVVGVPVVLASPGQWEQSKGLIYTGAGLWTGLVIVTSLVNSLVV
What is the function of this protein?
Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna.
What are the official names of this protein?
Photosystem II reaction center protein Z, PSII-Z.
What is the protein family that this protein belongs to?
Belongs to the PsbZ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein. Note=Associated with the photosystem II complex.
Protein: NS4_BTVBZ
Sequence: MVRGRNRRAARRKRAAKRLKMQMWIDAYILQWDLDQAQKDLENARTRMLTEEMERLEEEVEMLMRELELLERMEEDG
What is the function of this protein?
May function as a nucleic acid binding protein that modulates transcription of genes participating in the IFN response.
What are the official names of this protein?
Protein NS4.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Host nucleus, host nucleolus.
Protein: CH60_NOCAS
Sequence: MAKTIAYDEEARRGLERGLNSLADAVKVTLGPKGRNVVLEKKWGAPTITNDGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVREGLRNVAAGANPLGRKRGIEKAVEAVTAKLLDTAKEVETKEQIAATAGISAGDAAIGELIAEAMDKVGKEGVITVEESNTFGLQLELTEGMRFDKGYISGYFATDPERQEAVLEDPYILLVGSKVSTVKDLLPLLEKVIQAGKPLLIIAEDVEGEALSTLVVKKILGTFKSVAVKAPGGGDRRKAQLADIAILTGGQVISEEVGLSLETAGIELLGQARKVVVTKDETTIVEGAGDAEAIAGRVSQIRAEIENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVRNAKAAVEEGIVAGGGVAFLQSVPALDDFKLEGDEATGANIVRVALSAPLKQIAFNAGLEPGVLAEKVSNLPAGQGLNAQTNEDEDLLAAGVADPVKVTRSALQNAASIAALFLTTEAVVADKPEKASAAPATGHRFKMGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60, Heat shock protein 60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBP2A_MOUSE
Sequence: MKSLLLTILLLGLVAVLKAQEAPPDDLVDYSGIWYAKAMVHNGTLPSHKIPSIVFPVRIIALEEGDLETTVVFWNNGHCREFKFVMKKTEEPGKYTAFHNTKVIHVEKTSVNEHYIFYCEGRHNGTSSFGMGKLMGRDSGENPEAMEEFKNFIKRMNLRLENMFVPEIGDKCVESD
What is the function of this protein?
Involved in the regulation of systematic glucose homeostasis and insulin sensitivity (PubMed:27827363).  Involved in the regulation of liver lipid levels by positive regulation of hepatic lipogenesis and negative regulation of fatty acid beta-oxidation; via downstream transcriptional regulation of CPT1A and hepatic lipogenic program gene expression (PubMed:21908604).  May regulate hepatic lipogenesis and fatty acid beta-oxidation in an autocrine or paracrine manner (PubMed:21908604).
What are the official names of this protein?
Odorant-binding protein 2a, Epididymal-specific lipocalin-13.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ENO_RIPO1
Sequence: MLNKPEVLIEAITAREILDSRGRPTIEAEVLLETGAFGIAQVPSGASTGSFEAHELRDDDPARYAGKGVLTAVRNVKEKIAPQLLGTNAFDQASIDQKMIDRDGSSNKKELGANAILGVSLATAKAASAELDIPLYRYLGGPLANVLPVPMMNVLNGGSHADNNVDFQEFMIMPVGADSFTEGLRWGAEVFATLSKVLKERKLLSGVGDEGGYAPNLASNQEALDLLIEAIERSNYKPGEQIALAMDVASSEFYKDGQYVYDGSAHSPQEFIDYLAKLVSEYPIISIEDGLQEEDWDNWKLHTQSLGSRIQLVGDDLFVTNPTRLQRGIDLGVANSILIKLNQIGTLTETLETIALATRCQYTSVISHRSGETEDTTIADLAVATRAGQIKTGSLCRSERVAKYNRLLRIEEELGDRALYAPKVGLGPKF
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: AROQ_NITHX
Sequence: MARTIYVLNGPNLNMLGTREPETYGRATLADVEKLCADTAGDFGLAADCRQSNREGELIDFIHDAHAKKAAGIVINAGGYSHTSVALHDALVAVNIPTVEVHISNIHAREDFRHHSFTARAAFASLCGFGIDGYRLAINGLAAKIGAVKSGAKVKS
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: DNAK_BIFLD
Sequence: MARAVGIDLGTTNSCIATLEGGEPTVIVNAEGARTTPSVVAFSKSGEILVGEVAKRQAVTNVDRTISSVKRHMGSDWTVDIDGKKWTPQEISAQILMKLKRDAEAYLGEPVTDAVITCPAYFNDAQRQATKDAGKIAGLNVLRIINEPTAAALAYGLEKGKEDERILVFDLGGGTFDVSLLEIGKDDDGFSTIQVQATNGDNHLGGDDWDQKIIDWLVSEVKNKYGVDLSKDKIALQRLKEAAEQAKKELSSSTSTSISMQYLAMTPDGTPVHLDETLTRAHFEEMTSDLLGRCRTPFNNVLHDAGISVSDIDHVVLVGGSTRMPAVKELVKELTGGKEANQSVNPDEVVAVGAAVQSGVIKGDRKDVLLIDVTPLSLGIETKGGIMTKLIDRNTAIPTKRSEVFSTAEDNQPSVLIQVYQGEREFARDNKPLGTFELTGIAPAPRGVPQIEVTFDIDANGIVHVSAKDKGTGKEQSMTITGGSGLPKDEIDRMVKEAEAHEAEDKKRKEDAETRNQAEAFAYSTEKLVNDNKDKLSDDIVKEVTDKVNALKEALKGDDTEKVKTAQTELMTAAQKIGQVLYAQQGAEGAAAGADGAGASAGSASGSDDDTVEAEVVDDDDDKDNK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RDGC_NEIMB
Sequence: MWFKQISFYPLNKEKLPEADVLADKLAEAEFTHCQGLDWFSEGFTAPVSFSPELVFPADFTLRVALKKEEKVLPAGVIRDILEEKVAEIQNNEARNVGRKEKQELKEQITDDLLPRAFTRSSRTEAVFNTRHGYLLVNNAASAKAENILTKLREALGGLEASLPNTKQSPSSLMTGWLLQGHCEGGFELDSDCELKGTGDIVPVVKVSKQDLTADEVVQHVKNGKTVTQLGLVWREQIAFILTQDFTLKRIQYLDVLQEEAESNGDDAAGLAFASQILMAESVSTMLEELVSYLGGWQD
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RPN11_CANGA
Sequence: MERLQRLMMNTKVGAADANKDDTKETVYISSIALLKMLKHGRAGVPMEVMGLMLGEFVDEYTVNVVDVFAMPQSGTGVSVEAVDDVFQARMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNNRAVAVVVDPIQSVKGKVVIDAFRLIDTGALINNQEPRQTTSNSGLMNKANIQALIHGLNRHYYSLNIDYHKTPAETKMLLNLHKEQWQSGLKMQDYQEKETENLEATKRMVAVAQQYSKRIEEEKELSEEELKTRYVGKQDPKKHLAKTAENTLEENTVSVLTAGVNSIAIK
What is the function of this protein?
Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
What are the official names of this protein?
26S proteasome regulatory subunit RPN11.
What is the protein family that this protein belongs to?
Belongs to the peptidase M67A family.
Protein: ISPE_VIBC3
Sequence: MIHGTTVWPSPAKLNLFLYITGRRANGYHDLQTLFQFLDHGDELTITANNSGNITLSPALADVALEDNLIYKAAMALKNAAQSPLGADIQLHKVLPMGGGIGGGSSNAATTLVALNYLWQTGLSDDQLAEIGLALGADVPVFTRGFAAFAEGVGEELSAVEPEEKWYLVVRPAVSIATKDIFTHPQLMRNTPKRDLASLLTTPYENDCEKIVRSLYPEVDKQLSWLLQYAPSRLTGTGSCVFAEFSSRKDAQAVFAQLSDNVLAFVAQGRNVSPLRKTLADYQSAKIRPY
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: CAHM3_HUMAN
Sequence: MDKFRMLFQHFQSSSESVMNGICLLLAAVTVKLYSSFDFNCPCLVHYNALYGLGLLLTPPLALFLCGLLANRQSVVMVEEWRRPAGHRRKDPGIIRYMCSSVLQRALAAPLVWILLALLDGKCFVCAFSSSVDPEKFLDFANMTPSQVQLFLAKVPCKEDELVRDSPARKAVSRYLRCLSQAIGWSVTLLLIIAAFLARCLRPCFDQTVFLQRRYWSNYVDLEQKLFDETCCEHARDFAHRCVLHFFASMRSELQARGLRRGNAGRRLELPAVPEPPEGLDSGSGKAHLRAISSREQVDRLLSTWYSSKPPLDLAASPGLCGGGLSHRAPTLALGTRLSQHTDV
What is the function of this protein?
Pore-forming subunit of a voltage-gated ion channel, also permeable to larger molecules including ATP.  Together with CALHM1, forms a fast-activating voltage-gated ATP-release channel in type II taste bud cells (TBCs).  CALHM1-CALHM3-mediated ATP released acts as a neurotransmitter to gustatory neurons in response to GPCR-mediated tastes, including sweet, bitter and umami substances.
What are the official names of this protein?
Calcium homeostasis modulator protein 3, Protein A.
What is the protein family that this protein belongs to?
Belongs to the CALHM family.
What are the subcellular locations of this protein?
Basolateral cell membrane; Multi-pass membrane protein.
Protein: NUOD_LEPCP
Sequence: MAEIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRGTEKLAESKTFIQSLPYMDRLDYVSMMCNEHAYCLAIEKLMGIQVPERAQYIRVMFSEITRLLNHLLWLGCHGMDCGAMNMLIYCFREREDLFDMYEAVSGARMHAAYFRPGGVYRDLPDVMPQYKVSKIRNAKAMARLNENRQGSLLDFIDDFTKRFPTLVDEYETLLTDNRIWKQRTVGIGVLTPERALNLGLTGAMIRGSGIAWDLRKTQPYDVYDRMDFDIPVGVNGDTYDRYLVRVEEMRQSNRIIEQCSAWLRANPGPVITDNHKVAPPSRVEMKTSMEELIHHFKLFTEGFHVPEGEAYAAVEHPKGEFGIYAISDGANKPYRLKIRAPGFAHLAALDEMSRGHMIADAVAIIGTMDIVFGEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y1068_MYCMM
Sequence: MTRTDQDSWDLASSVGATATMVAAARALASAEANPIIDDPFAAPLVRAVGLDFFTRLAEGEIDHDEQAQRDRQLVADSIAVRTRFFDDFFLDAARRGVRQSVILAAGLDARAYRLPWPSGSVVYEVDQPDVIDFKDTTMSALGAVPTATRRTVRVDLRDDWPAALRHNGFDTTQPTAWSAEGLLMYLPPDAQDRLFDAISGLSAPGSRLATEYHPDPGSTMAERAQQFNQRWVRLGCDIDLSGLFYEGERSNVVDYLTEHGWHVAARPRQDLFTDYGRVFPDADTSQLRSIVAVTATFGEAG
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase MMAR_1068.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.