PharMolix/UniProtQA huggingface dataset:
Protein: DAD1_DEBHA
Sequence: MSESSTYFEKQRDMLIQEIGVSIESVVYNLDILNRSLNGSISVGKEFDNVGRLWSHFYDGLNQLKERNNQEETNKNDQGDANDDDSSSDEHGSSDEEIDQDQEN
What is the function of this protein?
Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation.  The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore (By similarity).
What are the official names of this protein?
DASH complex subunit DAD1, Outer kinetochore protein DAD1.
What is the protein family that this protein belongs to?
Belongs to the DASH complex DAD1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Associates with the mitotic spindle and the kinetochore.
Protein: EIF3C_DROMO
Sequence: MSRFFANGSDSESESSEEEVQASNFNKAANFQFSDDEEEVKRVVRSTKEKRYENLTSIIKTIRNHKKIKDIPNTLSSFEDLTRAYTKALPVISKEENGITPRFYIRCLAELEDFINEVWEDREGRKNLSKNNAKSLGTLRQKVRKYIKDFEEDLARFREAPDQESDVEEGEGEPHDSDGDRAGADSDDGVGAGTGKLAELPKAAKSAPTKAVADEDDSDDSIDWDSDTESETESSEDENLYQNMRERFLKRTTEKEDKDDDKRKDKRKEQKHKVRKRAEDDEDGEWETVVKGNVVEKPKMFEKDAEIDIPLVLAKLIEIMSARGKKRTDRRLQIDLLFELRDIAEQHALGTPISVKIHFNIISAIFDYNQKISEPMKLEHWALLLEVMQSMMKLLLANPDIIMNESVAEEHEEYVTAPFYIRGCPLAAVERLDDEFTKLLKECDPHSNDYVSRLKDEINVVKTIELVVQYFERCGNNNERCRIYLRKIEHLYYKFDPEVLKRKRGELPAAGTAPSSVEVMDKLCKFIYAKDDTDRIRTRAILAHIYHHAMHDNWFQARDLVLMSHLQDNIDAADPSTRILYNRMMANLGLCAFRQENIKDAHHCLVDLMVTGKPKELLAQGLLPQRQHERSAEQEKIEKQRQMPFHMHINLELLECVYLVSAMLLEIPYIAAHEFDARRRMISKTFYQQLRSSERQSLVGPPESMREHVVAAAKAMRCGNWQACANFIVNKKMNTKVWDLFYESERVREMLVKFIKEESLRTYLFTYSNVYTSISIPSLAQMYELPLPKVHSIISKMIINEELMASLDDPSETVVMHRSEPSRLQALAMQFVDKVTNLVDVNEKVFDMKQGNFFQRGNMGNRDRGYNRNQNNQGGNWGGQRRDNRNQRNRNQRGHHKQQQQQQQQQVQTIEEE
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit C, eIF3c, Eukaryotic translation initiation factor 3 subunit 8.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3259_HALH5
Sequence: MGRKWNNIKEKKAAKDKNTSRIYAKFGREIYVAAKQGEPDPELNQALKFVLERAKTYNVPKAIIERAIEKAKGGSDETFDELRYEGFGPSGSMVIVDALTNNVNRTASEVRAAFGKNGGNMGVSGSVAYMFDQTAIIGVQGKTEEDVLELLMEADLDVRDLVQEDEVTIVYAEPDQFHAVQEAFKQTGVEEFVVAEISMIPQTEVSLSQEDQEQFEKLIDVLEDLEDVQQVYHNVDLGE
What are the official names of this protein?
Probable transcriptional regulatory protein BH3259.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family. YeeN subfamily.
Protein: COAD_SHEPA
Sequence: MHKRAIYPGTFDPVTNGHADLIERAANLFEHVIIGIAANPSKQPRFTLAERVELLKTVTAHLDNVEVVGFSGLLVDFAKDQNASVLVRGLRAVSDFEYEFQLANMNRRLSPDLESVFLTPAEENSFISSTLVKEVALHGGDVSQFVHIEVANALTKKAK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YND5_YEAST
Sequence: MASYSLVESNSFGSENWCLKLQPSYKHGLLTGLSNGEIRLLDWSTGKSVQKIKASETAINDMKVIGSDFSAGHLVSSASIDAVKVFDIRTNDRIAQIQNEANSPFISLDSRHGLLACGTELQGIDAAVYIYDIRKWDTPLRSLIDSHHDDVTCIKFHPSDVNILLSGSTDGYTNIYDLKQDEEEDALHQVINYASIHSCGWLSPKRIFTLSHMETFAIHELNDKSDELKEPQPLDFGDVREIWNCDYVVDIYPGLIATGKTQENCGELCLLPFKDEKVDTENGIVIPHAHGDEVVRDIFIPAQHSNMLYSCGEDGCVKIWENKQGPLDIPENFWDYSKKMNVLGDDDREGSINLDEPLIIQKESVSTRPRKEKHKKAKKHSMKSRFKPY
What are the official names of this protein?
Uncharacterized WD repeat-containing protein YNL035C.
Protein: MLC_ECOLI
Sequence: MVAENQPGHIDQIKQTNAGAVYRLIDQLGPVSRIDLSRLAQLAPASITKIVREMLEAHLVQELEIKEAGNRGRPAVGLVVETEAWHYLSLRISRGEIFLALRDLSSKLVVEESQELALKDDLPLLDRIISHIDQFFIRHQKKLERLTSIAITLPGIIDTENGIVHRMPFYEDVKEMPLGEALEQHTGVPVYIQHDISAWTMAEALFGASRGARDVIQVVIDHNVGAGVITDGHLLHAGSSSLVEIGHTQVDPYGKRCYCGNHGCLETIASVDSILELAQLRLNQSMSSMLHGQPLTVDSLCQAALRGDLLAKDIITGVGAHVGRILAIMVNLFNPQKILIGSPLSKAADILFPVISDSIRQQALPAYSQHISVESTQFSNQGTMAGAALVKDAMYNGSLLIRLLQG
What is the function of this protein?
Transcriptional repressor that regulates the expression of proteins that are part of the phosphotransferase system for sugar uptake.  Regulates the expression of malT.
What are the official names of this protein?
Protein mlc, Making large colonies protein.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family.
Protein: GLYA_XYLFM
Sequence: MFPRDARLDMYDPELAKAIAAEVRRQEDHVELIASENYCSTLVMQVQGSQLTNKYAEGYSGKRYYGGCEYVDIAEQLAIERAKQLFGADYANVQPHSGSQANQAVYFALLQPGDTILGMSLAHGGHLTHGANVNVSGKLFNAVQYGVNAQGLIDYEAVESLALEHRPKMVVAGFSAYSQKIDWVRFRAIADQVGAYLLVDMAHVAGLVAAGVYPNPLPHAHVVTSTTHKTLRGPRGGIIVAQAPQEALVKKLQSIVFPGIQGGPLMHVIAAKAVAFKEALEPAFKVYQQQVVKNAKAMAETLMLRGYKIVSGGTENHLMLVDMIGRDVSGRDAEGALGQAHITVNKNAVPDDPRSPFVTSGLRLGTPAVTTRGYQEQDCVDLAHWIADVLDAPADATVIAAVREKVAAQCKKYPVYR
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AZUP_ALCFA
Sequence: MRNIAIKFAAAGILAMLAAPALAENIEVHMLNKGAEGAMVFEPAYIKANPGDTVTFIPVDKGHNVESIKDMIPEGAEKFKSKINENYVLTVTQPGAYLVKCTPHYAMGMIALIAVGDSPANLDQIVSAKKPKIVQERLEKVIASAK
What is the function of this protein?
This soluble electron transfer copper protein is required for the inactivation of copper-containing nitrite reductase in the presence of oxygen.  Serves as a direct electron donor to the nitrite reductase.
What are the official names of this protein?
Pseudoazurin, Blue copper protein, Cupredoxin.
What are the subcellular locations of this protein?
Periplasm.
Protein: MURG_WOLWR
Sequence: MDIILATGGTGGHIFPAIALAKALKTQGYNCILFTDKKTNKNTDIESYTLPLRRPSSNKFKFFLFLIYSSMLALYQVRKLKPKSVIGFGSYASFPTLLAARVLSIPIILHEQNTVLGRVNRFFFKSAKLIATSFPETKYAEGNKCIFTGNFVDIKAQSHSSTEKILNILVIAGSQGANFFDDVVSSVICDLPIKMKKKIRVTQQCTKKNVNKVKSLYKSEKIDCELSEFFDDMENRLANAHLVISRAGATSIAEITLARRSAIYIPYPYSKDNHQFYNAKYIEDSRAAIIVKQNSEAKKNLTEVLFDLLNNSQKLRDMTNSTEKTGIKNGTTEFVKVIVHRFS
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DCP1_ASHGO
Sequence: MTTARDNSATTLELYRKTLNFNVIGRYDPKIKQLLFHTPHATVYKWEAGENKWNKLEYQGVLAIYLRDVREQAELPVPHQEASAGAEGRCGEVLSGRDIYNYALIVLNRINPENFSIAIAPNSVVNKRRLFSPEENVQQPLEPMDVEVKDELVIIKNLRKEVYGIWIHTPTDRQNIYDLLKYLLENEPKDSFA
What is the function of this protein?
Component of the decapping complex necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay.  Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP.  Decapping is the major pathway of mRNA degradation in yeast.  It occurs through deadenylation, decapping and subsequent 5' to 3' exonucleolytic decay of the transcript body (By similarity).
What are the official names of this protein?
mRNA-decapping enzyme subunit 1.
What is the protein family that this protein belongs to?
Belongs to the DCP1 family.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Note=Is concentrated in several cytoplasmic foci called P bodies (or cytoplasmic processing bodies) which represent sites of mRNA decapping and 5' to 3' exonucleotidic decay.
Protein: Y2548_HALWD
Sequence: MNPIVISPAAIAAETDPIGIGAGTAPPGSYVLCVNLDAPTSMTIGAHGTAVLPAGGYAYVGSAFGSNGLGRVDRHRRVAMGIHDVTHWHIDYLISHQNASLTAIVVAPGADIECAITSSLLSRMKEPPLEGFGSSDCTCTAHLFISGSVTHIRNQCSTVIQELSASSN
What are the official names of this protein?
DUF123 domain-containing protein HQ_2548A.
Protein: ELNE_MOUSE
Sequence: MALGRLSSRTLAAMLLALFLGGPALASEIVGGRPARPHAWPFMASLQRRGGHFCGATLIARNFVMSAAHCVNGLNFRSVQVVLGAHDLRRQERTRQTFSVQRIFENGFDPSQLLNDIVIIQLNGSATINANVQVAQLPAQGQGVGDRTPCLAMGWGRLGTNRPSPSVLQELNVTVVTNMCRRRVNVCTLVPRRQAGICFGDSGGPLVCNNLVQGIDSFIRGGCGSGLYPDAFAPVAEFADWINSIIRSHNDHLLTHPKDREGRTN
What is the function of this protein?
Medullasin modifies the functions of natural killer cells, monocytes and granulocytes.  Inhibits C5a-dependent neutrophil enzyme release and chemotaxis (By similarity).  Capable of killing E. coli; probably digests outer membrane protein A (ompA) in E. coli (PubMed:10947984).
What are the official names of this protein?
Neutrophil elastase, Elastase-2, Leukocyte elastase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Elastase subfamily.
Protein: SDC1_ARATH
Sequence: MVGSLESDQTLSMATLIEKLDILSDDFDPTAVVTEPLPPPVTNGIGADKGGGGGEREMVLGRNIHTTSLAVTEPEVNDEFTGDKEAYMASVLARYRKTLVERTKNHLGYPYNLDFDYGALGQLQHFSINNLGDPFIESNYGVHSRPFEVGVLDWFARLWEIERDDYWGYITNCGTEGNLHGILVGREMFPDGILYASRESHYSVFKAARMYRMECEKVDTLMSGEIDCDDLRKKLLANKDKPAILNVNIGTTVKGAVDDLDLVIKTLEECGFSHDRFYIHCDGALFGLMMPFVKRAPKVTFNKPIGSVSVSGHKFVGCPMPCGVQITRMEHIKVLSSNVEYLASRDATIMGSRNGHAPLFLWYTLNRKGYKGFQKEVQKCLRNAHYLKDRLREAGISAMLNELSSTVVFERPKDEEFVRRWQLACQGDIAHVVVMPSVTIEKLDNFLKDLVKHRLIWYEDGSQPPCLASEVGTNNCICPAHK
What is the function of this protein?
Catalyzes the biosynthesis of ethanolamine from serine.  Highly specific for L-serine and does not attack D-serine, L-phosphoserine, phosphatidylserine, L-histidine L-glutamate L-tyrosine or L-tryptophan.  Decarboxylation of free serine is the major source of ethanolamine production in plants and ethanolamine metabolism is crucial for the synthesis of choline, phosphatidylethanolamine (PE) and phosphatidylcholine (PC), and thus for plant growth.
What are the official names of this protein?
Serine decarboxylase, AtSDC, Protein EMBRYO DEFECTIVE 1075, Serine decarboxylase 1, AtSDC1.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: LOLA_ALCBS
Sequence: MKKLLLTLAMVPAVLFSPTAWGDATDDLLGRLQTLESMKGGFEQVVLDQSGTHMQEALGKFQVARGNRFYWLTETPYEQMAASDGTTVWVYDKDLEQVVVRPLSQDLGQTPALLFGGKPADVAKAFTISERDNRGAEVTYRLTPKGQDPLFDQLDVTFKGGQPASMRLQDALGQQTVIDFIGLTLNDGIDSSLFHFDPPEGTDVIQQQQ
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PIMT_YERPG
Sequence: MVNKRMQTLLMQLRQQGIHDERLLQAIEAVPRERFVDEALAHKAYENTALPIGAGQTISQPYMVARMTELLQLTPTSRVLEIGTGSGYQTAILAHLVDHVCSVERIKGLQWQAKRRLKQLDLHNVSTRHGDGWLGWQSRGPFDAIIVTAAPPEIPDALLEQLDEGGILVLPVGEQFQTLKYVQRRNNEYHIETVEAVRFVPLVKGELA
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_SHELP
Sequence: MNNIIKMLNDEQMKQDVPEFGAGDTVVVKVRVVEGGKERLQAFEGVVIAKRNRGLHSAFTVRKISNGEGVERAFQTHSPLISSIEVKRRGRVRRAKLYYLRERSGKSARIREKLAK
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: SELO_SALPA
Sequence: MTLSFTARWRDELPATYTALLPTPLKNARLIWYNDELAQQLAIPASLFDATNGAGVWGGETLLPGMSPVAQVYSGHQFGVWAGQLGDGRGILLGEQLLADGSTLDWHLKGAGLTPYSRMGDGRAVLRSTIRESLASEAMHYLGIPTTRALSIVTSDTPVQRETQETGAMLMRLAQSHMRFGHFEHFYYRREPEKVQQLADFAIRHYWPQWQDVAEKYALWFEEVAARTGRLIAEWQTVGFAHGVMNTDNMSILGLTIDYGPFGFLDDYDPGFIGNHSDHQGRYRFDNQPSVALWNLQRLAQTLTPFIEIDALNRALDRYQDALLTHYGQRMRQKLGFFTEQKDDNVLLNELFSLMAREGSDYTRTFRMLSHTEQQSASSPLRDTFIDRAAFDAWFDRYRARLRTEAVDDALRQQQMQRVNPAIVLRNWLAQRAIDAAEQGDMAELHRLHEVLRQPFTDRDDDYASRPPEWGKRLEVSCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: COX2_GORBE
Sequence: MAHAAQVGLQDATSPIMEELIIFHDHALMIIFLICFLVLYALFLTLTTKLTSTNISDAQEMETVWTILPAIILVLIALPSLRILYMTDEINDPSFTIKSIGHQWYWTYEYTDYGGLIFNSYMLPPLFLEPGDLRLLDVDNRVVLPVEAPVRMMITSQDVLHSWAVPTLGLKTDAIPGRLNQTTFTATRPGLYYGQCSEICGANHSFMPIVLELIPLKIFEMGPVFTL
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL23_BRUMB
Sequence: MTDLRHYDVIVSPVITEKSTMVSEHNQVVFNVARKATKPEIKAAVEALFGVKVTAVNTAVCKGKVKRFRGLVGRQSDVKKAIVTLAEGQSIDVSTGL
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: Y5077_BACC4
Sequence: MIKPLIEFCVGNLASGSQAALEKLEKDPNLDVMEYGCLGYCGICFEGPFALVNGEVVQGATVEELVNNVYEYLDENPMF
What are the official names of this protein?
UPF0349 protein BCB4264_A5077.
What is the protein family that this protein belongs to?
Belongs to the UPF0349 family.
Protein: MGSA_BACAC
Sequence: MKIALIAHDKKKEDMVSFAYAYKPIFEQHELFATGTTGLRIMEATGLVVTRYQSGPLGGDQEIGAMIAKNDLDMVIFFRDPLTAQPHEPDVNALLRLCDVYAIPLATNMASAEMLMHALERGDLDYRKLRK
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: ATPA_ALIB4
Sequence: MGAKIQADEISSIIKERIDNFELNVDVNETGKIISYADGIAQVYGLKNVMAGEIVEFENGEKGLASNLEESSVGVVILGKGEGLREGTSCKRVGKLLETPVGEALVGRVVNALGEPIDGKGAIAATETRFVEEKAPGIMARKSVHEPLQTGIKAIDALVPIGRGQRELIIGDRQTGKTTVAIDTILNQKGENVICIYVAIGQKSSSIASVVRTLEESGAMDYTIVVNASAADSSALQFLAPYTGVTIGEYFRDNGKHALIIYDDLSKHAVAYREMSLILRRPPGREAYPGDVFYLHSRLLERAAKMSDERGAGSMTALPIIETQAGDVAAYIPTNVISITDGQIFLETNLFNSGIRPAINVGLSVSRVGGAAQIKATKQVAGTLKLSLAQYRELEAFAQFASDLDEATRRELELGQRMVEVLKQGVNKPLVIEKQIVIIYAGTKGYLNDIAVKDVVRFEAELHAFFEQKYSNILEAIKASQKIDDNTETQLKAALEEFKTVFNAN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DNRV_STRS5
Sequence: MTRFAPGAPAWFDLGSPDVAASADFYTGLFGWTATVVSDPGAGGYTTFSSDGKLVAAVARHQIDTPYHRPYGPGNDQHGMPAIWTVYFATNDADALTKRVETAGGDVIMTPMDVLGLGRMAVFADPSGAAFAVWRKGVMEGAEVTGVPGSVGWVELVTDDIGTARGFYRATLGLAPADTGRKGVTDPVWHIHDTPVAGTRELGTTGAVRPHWAVLFSVHDCDATVRRAVELGGSVENEPVDTPRGRRADLLDPHGAGFSVVELREAYPAAADGAS
What is the function of this protein?
Involved in the biosynthesis of the anthracyclines carminomycin and daunorubicin (daunomycin) which are aromatic polyketide antibiotics that exhibit high cytotoxicity and are widely applied in the chemotherapy of a variety of cancers.  Acts jointly with DoxA in the conversion of 13-deoxycarminomycin and 13-deoxydaunorubicin to yield carminomycin and daunorubicin, respectively (By similarity).
What are the official names of this protein?
Anthracycline biosynthesis protein DauV.
Protein: AROB_NEIGO
Sequence: MKTLTVHTPSHSYPIFIGNGLLPQAGSLLKPHLGKRAAIITNETVAPLYLGTLQTALDAAGVSHFSIILPDGEAHKNWQTLNLIFDGLMQNRAERKTTLIALGGGVIGDMVGFAAATYQRGAPFIQIPTTLLSQVDSSVGGKTAINHPLGKNMIGAFYQPQAVLADLDTLHTLPARELSAGMAEVIKYGALGDIGFFEWLEQHMPELMTLERAPLTQAVYRCCQMKADIVAQDETEQGIRAWLNLGHTFGHAVEAEMGYGVWLHGEAVAAGCVLAARLSEQLGKTSAADTARLAALLEAAGLPSAPPVFAFEKWLAHMSHDKKVSGGIMRFIGLNRLGEAVITEITDTDILRRTLQPYL
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREG_SORC5
Sequence: MHDPGEHGHGRHDHDHDHDHVHDHDHDHDHVHGGGHRHAHEHEHAHEHAHGHEHGHAHAHAHAHAHEHAHGHTHEHWAHPGLFSERDAPKDRDFSARAFTVGIGGPVGSGKTALVLALCRALRDRMPLGVVTNDIFTQEDAEFLHRNKALPPERIRAVETGGCPHAAIREDISHNLVALDDLMDHVAPALLIVESGGDNLAAQYSRELVDYTIYVIDVAGGDKVPRKGGPGITQSDLLVINKTDLAPHVGADLGVMERDARRMRGDGPFLFAQCNRSQGVPEIIDHILSAMRRATTTAPPAK
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AT222_PENRW
Sequence: MLSYISAAFQSPSPDEGVQQRPPRYVGEDTTPTSRREILGWYSYGIAAEVFAVCGVGSFLPLTLEQLARERGTLQTSRLPCVGPSAGNSTNATEHGQCVVPVFGLEINTASFAMYTFSLAVLIQALTLISFSALADYENNRKTLLMVFGFAGALASMLFVFIAPPLFVIGSILVVVGVTCLGSSFVVLNSYLPVLVANDPSLQEGKADDGTEMSSFDRDEGDSEGNPWGKDHTDNDSLDGLQPSDQPQSSLEGGMGTKAPLSSSPELQLSTKISSRGIGLGYCAAVFVQIISIIMLLTLSKTKLAKVSATLPMRFVLLLVGIWWGAFTLVTRNLLKTRPGPRLDTVSTKGTGRWRAWLRLVGFAWKSLWETVKVVSKLREVLIFLVAWFLLSDAMATVSGTAILFARTELKLSTPLIGLLSITATLSGMTGAFLWPQVSRYFRLQPSHTIILCIALFEMIPLYGLLAYIPFIKNWGVFGLQQPWEIFPLAIVHGVVSGGLASYCRSFFGLLIPPGSEAAFYALYAATDKGSSFIGPAIVGGIVDATGQIRSGFFFMAILIVLPIPLVWMVNADKGRREGLAMAETLGKSHGGPAEDAQEAEGLLARE
What is the function of this protein?
Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation.  The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation (By similarity).
What are the official names of this protein?
Autophagy-related protein 22-2.
What is the protein family that this protein belongs to?
Belongs to the ATG22 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Vacuole and punctate structures.
Protein: CAT4_MORMO
Sequence: MKNYFDSPFKGELLSEQVKNPNIKVGRYSYYSGYYHGHSFDECARYLHPDRDDVDKLIIGSFCSIGSGASFIMAGNQGHRHDWASSFPFFYMQEEPAFSSALDAFQRAGDTAIGNDVWIGSEAMIMPGIKIGDGAVIGSRSLVTKDVVPYAIIGGSPAKQIKKRFSDEEISLLMEMEWWNWPLDKIKTAMPLLCSSNIFGLHKYWREFVV
What is the function of this protein?
This enzyme is an effector of chloramphenicol resistance in bacteria.
What are the official names of this protein?
Chloramphenicol acetyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: Y663_STRPN
Sequence: MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGHIGKESSQEIGELIVETILDILGSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPTLHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHAHVTALASRPKLIGGARAHYPQDAIRKF
What are the official names of this protein?
UPF0340 protein SP_0663.
What is the protein family that this protein belongs to?
Belongs to the UPF0340 family.
Protein: THRC_MYCTO
Sequence: MTVPPTATHQPWPGVIAAYRDRLPVGDDWTPVTLLEGGTPLIAATNLSKQTGCTIHLKVEGLNPTGSFKDRGMTMAVTDALAHGQRAVLCASTGNTSASAAAYAARAGITCAVLIPQGKIAMGKLAQAVMHGAKIIQIDGNFDDCLELARKMAADFPTISLVNSVNPVRIEGQKTAAFEIVDVLGTAPDVHALPVGNAGNITAYWKGYTEYHQLGLIDKLPRMLGTQAAGAAPLVLGEPVSHPETIATAIRIGSPASWTSAVEAQQQSKGRFLAASDEEILAAYHLVARVEGVFVEPASAASIAGLLKAIDDGWVARGSTVVCTVTGNGLKDPDTALKDMPSVSPVPVDPVAVVEKLGLA
What is the function of this protein?
Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.
What are the official names of this protein?
Threonine synthase, TS.
What is the protein family that this protein belongs to?
Belongs to the threonine synthase family.