PharMolix/UniProtQA huggingface dataset:
Protein: APOE_RATRT
Sequence: MKALWALLLVPLLTGCLAEGELEVTDQLPGQSNQPWEQALNRFWDYLRWVQTLSDQVQEELQSSQVTQELTVLMEDTMTEVKAYKKELEEQLGPVAEETRARLAKEVQAAQARLGADMEDLRNRLGQYRNEVNTMLGQSTEELRSRLSTHLRKMRKRLMRDADDLQKRLAVYKAGAQEGAERGVSAIRERLGPLVEQGRQRTANLGSGAAQPLRDRAQALSDRIRGRLEEVGNQARDRLEEVRDQMEDVRSKMEEQTQQIRLQAEVFQARLKGWFEPLVEDMQRQWANLMEKIQASVATNSIASTTVPLENQ
What is the function of this protein?
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids.  APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance.  Apolipoproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma.  As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL).  It also binds a wide range of cellular receptors including the LDL receptor/LDLR, the LDL receptor-related proteins LRP1, LRP2 and LRP8 and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles.  Finally, APOE has also a heparin-binding activity and binds heparan-sulfate proteoglycans on the surface of cells, a property that supports the capture and the receptor-mediated uptake of APOE-containing lipoproteins by cells.  A main function of APOE is to mediate lipoprotein clearance through the uptake of chylomicrons, VLDLs, and HDLs by hepatocytes.  APOE is also involved in the biosynthesis by the liver of VLDLs as well as their uptake by peripheral tissues ensuring the delivery of triglycerides and energy storage in muscle, heart and adipose tissues.  By participating in the lipoprotein-mediated distribution of lipids among tissues, APOE plays a critical role in plasma and tissues lipid homeostasis.  APOE is also involved in two steps of reverse cholesterol transport, the HDLs-mediated transport of cholesterol from peripheral tissues to the liver, and thereby plays an important role in cholesterol homeostasis.  First, it is functionally associated with ABCA1 in the biogenesis of HDLs in tissues.  Second, it is enriched in circulating HDLs and mediates their uptake by hepatocytes.  APOE also plays an important role in lipid transport in the central nervous system, regulating neuron survival and sprouting.
What are the official names of this protein?
Apolipoprotein E, Apo-E.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix. Note=In the plasma, APOE is associated with chylomicrons, chylomicrons remnants, VLDL, LDL and HDL lipoproteins. Lipid poor oligomeric APOE is associated with the extracellular matrix in a calcium- and heparan-sulfate proteoglycans- dependent manner. Lipidation induces the release from the extracellular matrix.
Protein: THIG_VIBA3
Sequence: MLTIADKTFQSRLFTGTGKFANKHLMASAIEASGSQLATMALKRVDIRSEQDDILQPIIDAGVNLLPNTSGAKNAKDAIFAAHLAREALGTNWLKLEIHPDPKYLMPDPIETLKAAEQLVKDGFVVLPYCHADPVLCKRLEEVGCAAVMPLGAPIGSNKGIASADFLEIIIDQANVPVIVDAGIGAPSHAARAMEMGADAVLVNTAIAASQQPVEMAIAFKLAVEAGRMAYLAGLAGKVSHAVASSPLTSFLDE
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCOR_PANRE
Sequence: MTLTGCVDYYEIIAGTKVAVCRNAIDNKTVATAIAATRTVNGNDDPFVVMNVSTIMAKVIQWQRTMPRVAPCYAVKCNDDKVLLRTLADLGMGFDCASKAEIEKVIGLVGPEKIVYANPCKTRGFIAHAEAAGVKRMTFDSVEELTKIKQNHADPSLILRISVSDPTAQCQLGIKFGCDPETVAPKLLRKAADMGMNVIGISFHVGSGCNEPATFRTALEYARGLFDLGISLGLSMTLLDIGGGFPGVDTAHISLDACAAVINPALEELFPLDSCPDVEVIAEPGRYFACAAVSVTTNVIASVKVPASRITEKADDVNRDGYMYYMNDGVYGSFNCKLFDHYQPRGMPLAEHDADEPRFPVCVWGPTCDGLDQVEESSVMPRLYEGDWLYYPDMGAYTSVAASTFNGFDKPKTYYFIDEATLGSIVRKADSAPRG
What is the function of this protein?
Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine.  Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis.
What are the official names of this protein?
Ornithine decarboxylase, ODC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family.
Protein: RSXD_SALTI
Sequence: MVFRIASSPYTHNQRQTSRIMLLVLIAALPGIAAQTWFFGWGTLFQIVLAAITALVAEAIVLRLRKQSVASHLQDYSALLTGLLLAVSIPPLAPWWMVVLGTGFAIIIAKQLYGGLGQNPFNPAMIGYVVLLISFPVQMTSWLPPYEIAATTPDILDTLRMIFSGHTASGGDMTLLRIGIDGISQATPLDTFKTSLRAGHSVEQIMQYPIYSGALAGVGWQWVNLAWLVGGVFLLWQKAIRWHIPVSFLLTLALCAALGWLFSPATLASPQLHLLSGATMLGAFFILTDPVTASTTNRGRLIFGALAGVLVWLIRSFGGYPDGVAFAVLLANITVPLIDYYTRPRVYGHRKG
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit D, Rsx electron transport complex subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SRPK_PHYPO
Sequence: MENIFKEKEKGKEKAKEEEKENDSGDLFDSEDEGTEDYKKGGYHPVKVGEVYKSNYRIVKKLGWGHFSTVWLAIDEKNGGREVALKIVKSASHYREAAEDEIHLLQTISEGDPESKYCVVKLLDSFLHTGPHGKHICMVFEKLGSNLLDLIKLHNYKGIPLPLVKCMTKQILIGLDYLHTKCKIIHTDLKPENVLLDHLLRPDTLNWDDQFLDGASSSSPISNDAENARQTRSGKIKWEPSARIADSLSRKIVKVPIVKIADLGTACWTHKHFTDDVQTRQYRCPEVILGQKWDTTIDMWSLACMVFELATGDLLFCPKKGDKYDKTDDHLALMIELLGRMPRSFITKGSKSEKYFNSKGELKYIRKLGPQWGMSDVLYEKYRFPKEEADKLSAFLLPMLQYEPEKRATARDSLEHPYMADVPPFL
What is the function of this protein?
Phosphorylates serine/arginine-rich protein PSR.
What are the official names of this protein?
Serine/threonine-protein kinase SRPK, PSRPK.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PTH_LACCB
Sequence: MKMIVGLGNPGQKYAGSKHNMGFMVVDGLAKRLNLTIDKLEFDAATATTRLNGEKIFLVKPQTFMNASGRAVRELMMFYQIQLDEIFVVQDDMDLTLGKLRLRKRGSAGGHNGIKDIISATGSDEFCRLKIGIQHPQRQRVVDWVLTPFSKTDQPLIDDAIEKADDALEDWLNGMPFDQLMNKFN
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_ORYSA
Sequence: MVREEVAGSTQTLQWKCVESRVDSKRLYYGRFILSPLRKGQADTVGIALRRALLGETEGTCITHAKFGSVPHEYSTIAGIEESVQEILLNLKEIVLRSNLYGVRTASICVKGPRYITAQDIILPPSVEIVDTAQPIANLTEPTDFRIELRIKRDRGYHTEVRKNTQDGSYPIDAVSMPVRNVNYSIFACGNGNAKYEILFLEIWTNGSLTPKEALYEASRNLIDLFLPFLHTEEEGTRFQENKNRFTSPLLSFQKRLTNLKKNKKRIPLNCIFIDQLELPSRTYNCLKRANIHTLLDLLSKTEEDLMRIDSFRMQDGKQIWDTLEKHLPMDLPKNKF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ATG18_CANGA
Sequence: MPNKAVSIYYLNFNQTGTCISMGTSNGFLIFNCAPFGKFYSEDSGGYGIVEMLFSTSLLALVGIGDQPMLSPRRLRIINTKKHSIICEVTFPTKILSVKMNRSRIVVVLKEQIYIYDINNMRLLHTIEIAPNPEGLVALSCNTDTNLLAYPSPPKVISSDINPNVNTNTINIARSKSEELIANSKDNNLQNKFGTTLEGQQNIDEDKAANGYQVDQNTDTAENDINSGDVIIYDMSTLQPLMVIEAHKGEIAALNFSFDGSLIATASEKGTIIRVFSTSSGAKLYQFRRGTYPTKIYSLSFSQDNRFLSVTCSSKTVHIFKLTKTGEERTSGGADDADSDDSGNENDGDNNSVGNGDVSSLLSDNDIESTREPYVDASRKTMGRMIRNSSQKLSRRAAKTLGQLFPIKVTSILEPSRHFASLKLPTDSNISGNVKTLCSIGNEMEVDKVEYPELFDGQDQGDRTKVTMLPIRVISSEGYLYNYVLDPERGGDCLLLSQYSTAIDQ
What is the function of this protein?
The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).  Necessary for proper vacuole morphology.  Plays an important role in osmotically-induced vacuole fragmentation.  Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation-induced autophagy.  Involved in correct ATG9 trafficking to the pre-autophagosomal structure.  Might also be involved in premeiotic DNA replication (By similarity).
What are the official names of this protein?
Autophagy-related protein 18.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PROPPIN family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein.
Protein: Y2112_STRP1
Sequence: MTHNHENDHQHEVITLVDEQGNETLFEILLTIDGREEFGKNYVLLVPAGSEEDESGEIEIQAYSFTENEDGTEGDLQPIPEDSDAEWDMIEEVFNSFLDEN
What are the official names of this protein?
UPF0473 protein SPy_2112/M5005_Spy1795.
What is the protein family that this protein belongs to?
Belongs to the UPF0473 family.
Protein: RL24E_METTH
Sequence: MRVCSFCHEEIEPGTGKMYVKRDGTIYFFCSSKCEKNMIKLGRVPRKVKWVKK
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L24e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL24 family.
Protein: SODC_MACFU
Sequence: MAMKAVCVLKGDSPVQGTINFEQKESNGPVKVWGSITGLTEGLHGFHVHQFGDNTQGCTSAGPHFNPLSRQHGGPKDEERHVGDLGNVTAGKDGVAKVSFEDSVISLSGDHSIIGRTLVVHEKADDLGKGGNEESKKTGNAGGRLACGVIGIAQ
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn].
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RS10_STRP7
Sequence: MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPTERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: LGT_GLUOX
Sequence: MSHPLIFPDFDPVAFHIGPLAVRWYALAYMVSFIIALPIARRLNRLAPEVATNEQVDDFLFYAILGVLLGGRLGYVLFYRPMDYLSHPLEIFKTWDGGMSFHGGALGVILALAYFSWKTRLSFLAFADRIVPVVPIGLGLGRCANFVNGELWGRPASPDLPWAMIFPTGGPIPRHPSELYEALTEGVLLLCVMLFAASRPQVRERFGFLSGLFLFGYACARSFCEFFRQPDANIGFLSGGTTMGQLLCIPMALAGMGLMVYAMRRPAQVSAHV
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FMT_BORBR
Sequence: MRLVFAGTPEFARIALDALLAAGHDVPLVLTQPDRPAGRGLKLTPSPVKQAALAAGIEVAQPRSLRLDGRYPDEAAAARAQLERVAPDVMVVAAYGLILPQWTLDLPRLGCLNIHASLLPRWRGAAPIQRAIEAGDAETGVTIMQMDAGLDTGDMLLERAVPIGAQQTAAQLHDELALAGGQAIVDALAALGQGGLAPRRQPDAGVTYAAKLDKAEAALDCSLPAAVLARRVRAFNPVPGATIRLPGLDDPVKVWRAQALEQAAGGPPGAVLRADAQGIDIATGQGVLRLLELQKAGGKRQPVDVFVRGWQP
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: LIPB_BURCH
Sequence: MSVSPVSIVSTPVAVSASPAGAPDQPVQPVTVRWRGREAYEASFDAMRAFTDTRTADTGDEIWVVEHPPVYTLGQAGDPAHLLVADSGVPLVKVDRGGQITYHGPGQIVVYLLLDLRRRKLMVRTLVTKIEEAVIETLAAYNLASVRKAGAPGIYVASGVHEGAKIAALGLKIRNGCSYHGLSLNVKMDLRPFLAINPCGYAGLETVDMASLEVAADWNDVAHTLVGRLIANLDGASAAADKPHALEQSND
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T7L1A_DANRE
Sequence: MPQLNGGGGDDLGANDELISFKDEGEQEEKISENVSSERDLDEVKSSLVNESENNSSSSDSEQTDRRPRPRPDLESYEKQREYFAEALRRQQDGGFFKGPPYAGYPFLMIPDITNPYLSNGSLSPSTRTYLQMKWPLLDVPASAALKDSRSPTPGHLSNKVPVVQHPHHVHPLTPLITYSNEHFSPGTPPSHLSPEILDPKTGIPRTPHPSELSPYYPLSPGAVGQIPHPLGWLVPQQGQHMYSIPPGGFRHPYPALAMNASMSSLVSSRFSPHMVPHPPHGLHQTGIPHPAIVSPAIKQEPNGESPSNSTHGKPSVPVKKEEEKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHSLSREEQAKYYELARKERQLHSQLYPGWSARDNYGKRKKRKRDCKSDSPSESNFSPQPKKQCVPYLSSEKMCDSPTSSHGSMLDSPATPSAALASPAAPAATHSEQAQPLSLTTKPEGRAHHNHPHFPLPGKSSGSGSGSSMALHSLSRPIPFTSLPPSLLGPNSPFHQAALHSHHALLQTQPLSLVTKSVE
What is the function of this protein?
Participates in the Wnt signaling pathway.  Probably binds to DNA and acts as a repressor in the absence of ctnnb1, and possibly as an activator in its presence.  Required early in development for dorsal specific gene activation and during gastrulation for repression of dorsal-specific genes in the marginal zone.  Required for head formation and forebrain specification.  Regulates anterior-posterior patterning in the neuroectoderm by repressing posterior neural fates.
What are the official names of this protein?
Transcription factor 7-like 1-A, HMG box transcription factor 3-A, TCF-3, TCF-3-A, zTcf-3, Protein headless.
What is the protein family that this protein belongs to?
Belongs to the TCF/LEF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: THII_BACAC
Sequence: MMTYEYILVRYGEMTTKGKNRSKFVSTLKDNVKFKLKKFPNIKIDATHDRMYIQLNGEDHEAVSERLKDVFGIHKFNLAMKVPSELEDIKKGALAAFLQVKGDVKTFKITVHRSYKHFPMRTMELLPEIGGHILENTEDITVDVHNPDVNVRVEIRSGYSYIMCDERMGAGGLPVGVGGKVMVLLSGGIDSPVAAYLTMKRGVSVEAVHFHSPPFTSERAKQKVIDLAQELTKYCKRVTLHLVPFTEVQKTINKEIPSSYSMTVMRRMMMRITERIAEERNALAITTGESLGQVASQTLDSMHTINEVTNYPVIRPLITMDKLEIIKIAEEIGTYDISIRPYEDCCTVFTPASPATKPKREKANRFEAKYDFTPLIDEAVANKETMVLQTVEVVAEEEKFEELF
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BORG1_MOUSE
Sequence: MSTKVPIYLKRGSRKGKKEKLRDLLSSDMISPPLGDFRHTIHIGSGGGDDMFGDISFLQGKFHLLPGTAVEEAEEDGSFDLPFQFTRTTTVCGRELPDGLSPLLKNAISLPVIGGPQALTLPTAQAPPKPPRLHLESPQPSPQPSPQGAGNVDVWRIPEAGSPHNGMSPEPEAEEPFLSHASSLLSLHVDLGPSILDDVLQIMDHDLGRVQIPT
What is the function of this protein?
Probably involved in the organization of the actin cytoskeleton.  May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes.  Induces pseudopodia formation in fibroblasts in a CDC42-dependent manner (By similarity).
What are the official names of this protein?
Cdc42 effector protein 2, Binder of Rho GTPases 1.
What is the protein family that this protein belongs to?
Belongs to the BORG/CEP family.
What are the subcellular locations of this protein?
Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton.
Protein: MURC_GEOKA
Sequence: MTAYHFVGIKGTGMSALAQVLHDLGYTVQGSDVEKWFFTQKALEERGIPVLPFSKDNIRPGYTVIAGNAFPDTHEEIEAARQLGVPVIRYHRFLGQLAGKFTSIAVTGSHGKTTTTGLLAHVMQGAHPTSYLIGDGTGKGEPGSKYFVFEACEYRRHFLSYFPDYAIMTNIDFDHPDYFANVDDVFSAFQQMANQVKKAIVACGDDPYLPNIQAKVPILFYGFGEENDFQARNIVKTTEGMAFDVFVRNTFFASFAIPRFGTHNVLNALAVIALCHYEGVDAGTIAKRLQTFQGVKRRFSEKTVGRQVLIDDYAHHPREITATLEAARQKYPGREVVAIFQPHTYTRTQTFLREFAESLLQADHVYLCDIFGSAREHEGKLTIRDLQAQIPRSQLLEEQNVAVLKQHQDAVLVFMGAGDIQKFQQAYERAVLSA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XYLG_ECO57
Sequence: MPYLLEMKNITKTFGSVKAIDNVSLRLNAGEIVSLCGENGSGKSTLMKVLCGIYPHGSYEGEIIFAGEEIQASHIRDTERKGIAIIHQELALVKELTVLENIFLGNEITHNGIMDYDLMTLRCQKLLAQVSLSISPDTRVGDLGLGQQQLVEIAKALNKQVRLLILDEPTASLTEQETSVLLDIIRDLQQHGIACIYISHKLNEVKAISDTICVIRDGQHIGTRDAAGMSEDDIITMMVGRELTALYPNEPHTTGDEILRIEHLTAWHPVNRHIKRVNDVSFSLKRGEILGIAGLVGAGRTETIQCLFGVWPGQWEGKIYIDGKQVDIRNCQQAIAQGIAMVPEDRKRDGIVPVMAVGKNITLAALNKFTGGISQLDDAAEQKCILESIQQLKVKTSSPDLAIGRLSGGNQQKAILARCLLLNPRILILDEPTRGIDIGAKYEIYKLINQLVQQGIAVIVISSELPEVLGLSDRVLVMHEGKLKANLINHNLTQEQVMEAALRSEHHVEKQSV
What is the function of this protein?
Part of the ABC transporter complex XylFGH involved in xylose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Xylose import ATP-binding protein XylG.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Xylose importer (TC 3.A.1.2.4) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL331_MYCPN
Sequence: MAVKRSTRLGCNDCREINYLTFKNVKKNPEKLALNKFCSRCRKVVVHKEVKRK
What are the official names of this protein?
50S ribosomal protein L33 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: GRAP1_HUMAN
Sequence: MAQALSEEEFQRMQAQLLELRTNNYQLSDELRKNGVELTSLRQKVAYLDKEFSKAQKALSKSKKAQEVEVLLSENEMLQAKLHSQEEDFRLQNSTLMAEFSKLCSQMEQLEQENQQLKEGAAGAGVAQAGPLVDGELLRLQAENTALQKNVAALQERYGKEAGKFSAVSEGQGDPPGGLAPTVLAPMPLAEVELKWEMEKEEKRLLWEQLQGLESSKQAETSRLQEELAKLSEKLKKKQESFCRLQTEKETLFNDSRNKIEELQQRKEADHKAQLARTQKLQQELEAANQSLAELRDQRQGERLEHAAALRALQDQVSIQSADAQEQVEGLLAENNALRTSLAALEQIQTAKTQELNMLREQTTGLAAELQQQQAEYEDLMGQKDDLNSQLQESLRANSRLLEQLQEIGQEKEQLTQELQEARKSAEKRKAMLDELAMETLQEKSQHKEELGAVRLRHEKEVLGVRARYERELRELHEDKKRQEEELRGQIREEKARTRELETLQQTVEELQAQVHSMDGAKGWFERRLKEAEESLQQQQQEQEEALKQCREQHAAELKGKEEELQDVRDQLEQAQEERDCHLKTISSLKQEVKDTVDGQRILEKKGSAALKDLKRQLHLERKRADKLQERLQDILTNSKSRSGLEELVLSEMNSPSRTQTGDSSSISSFSYREILREKESSAVPARSLSSSPQAQPPRPAELSDEEVAELFQRLAETQQEKWMLEEKVKHLEVSSASMAEDLCRKSAIIETYVMDSRIDVSVAAGHTDRSGLGSVLRDLVKPGDENLREMNKKLQNMLEEQLTKNMHLHKDMEVLSQEIVRLSKECVGPPDPDLEPGETS
What is the function of this protein?
Functions as a scaffold protein to facilitate MAP3K1/MEKK1-mediated activation of the JNK1 kinase by phosphorylation, possibly by bringing MAP3K1/MEKK1 and JNK1 in close proximity.
What are the official names of this protein?
GRIP1-associated protein 1, GRASP-1.
What are the subcellular locations of this protein?
Early endosome membrane; Peripheral membrane protein. Recycling endosome membrane; Peripheral membrane protein. Cell projection, axon. Cell projection, dendrite. Synapse. Note=Localizes to recycling endosomal tubules that are emanating from early endosomes.
Protein: RL34_COLP3
Sequence: MKRTFQPSVLKRKRNHGFRARMATKNGRAVIARRRAKGRARLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: QCR9_NEUCR
Sequence: MSALYNLIFRNNTAFVGAVFAGAFAFELAYDNGMDKVWDKINKGRQWKDIRHKYVEAEE
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol.  In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
What are the official names of this protein?
Cytochrome b-c1 complex subunit 9, mitochondrial, Complex III subunit 9, Complex III subunit IX, Ubiquinol-cytochrome c oxidoreductase subunit 9, Ubiquinol-cytochrome c reductase complex 8 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the UQCR10/QCR9 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: AIM18_LACTC
Sequence: MIRALARGATIPRSFHYIQYYQKRNLLTHGLKKKHIPPYKTILALGAGAFISGLFMLQKDSITNDAGPIENSESSVEVDKSVSPFTVVLSPPETLLTTKYTLLGFGPRSVTFLGFKVYALGIYVANEDLPLIPKILNPTYLCKAFLDTDSAKSHSENVGAALKDATKSRVLVGSLIDGGVRFMAKITPIRNTDFNHLKDGLVKSILNHPECQKNQEAVSRGLQELKNAFTRKGSVPKNDDLIIELQANGSLQLSYRSRKQNECMMLGRVDEPLIGKFLFSQYLGGDKPLSPPTRETFAQKVKTLV
What are the official names of this protein?
Altered inheritance of mitochondria protein 18, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AIM18/AIM46 family.
What are the subcellular locations of this protein?
Mitochondrion.