Protein: TEN1_MOUSE
Sequence: MEQTDCKPYQPLSKVKHEMDLAYTSSSDESEDGRKPRQSFNSRETLHEYNQELRRNYNSQSRKRKDVEKSTQEIEFCETPPTLCSGYHTDMHSVSRHGYQLEMGSDVDTETEGAASPDHALRMWIRGMKSEHSSCLSSRANSALSLTDTDHERKSDGENGFKFSPVCCDMEAPADSAQDMQSSPHNQFTFRPLPPPPPPPHACTCARKPPPTVDSLQRRSMTTRSQPSPAAPAPPTSTQDSVHLHNSWVLNSNIPLETRHFLFKHGSGSSAIFSAASQNYPLTSNTVYSPPPRPLPRSTFSRPAFTFNKPYRCCNWKCTALSATAITVTLALLLAYVIAVHLFGLTWQLQPVGQIYANGISNGNPGTESMDTTYSPIGGRVSDKSEKKVFQKGRAIDTGEVDIGAQVMQTIPPGLFWRFQITIHHPIYLKFNISLAKDSLLGIYGRRNIPPTHTQFDFVKLMDGKQLVKQDSKSSDDIQHSPRNLILTSLQETGFIEYMDQGPWYLAFYNDGKKMEQVFVLTTAIEIMDDCSTNCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRNGWKGPECDVPEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSSHGICVKGECHCSTGWGGVNCETPLPICQEQCSGHGTFLLDTGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQCEEGWVGPTCEERSCHSHCAEHGQCKDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNIVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYVSPLCQGSPDPLDLIQQSQPLFSQHTSRLFYDRIKFLIGKDSTHVVPQDISFDSRRACVIRGQVVAVDGTPLVGVNVSFLHHSDYGFTISRQDGSFDLVAIGGISVVLIFDRSPFLSEKRTLWLPWNQFIVVEKVIMQRIVADAPSCDISNFISPNPIVLPSPLTSFGGSCPERGTIVPELQVVQEEIPIPSSFVRLSYLSSRTPGYKTLLRILLTHSTIPVGMIKVHLTVSVEGRLTQKWFPAAINLVYTFAWNKTDIYGQKVWGLAEALVSVGYEYEMCPEFILWEQRTVVLQGFEMDASNLGGWSLNKHHIFNPQSGIIHKGNGENMFISQQPPVIATIMGNGHQRSVACTNCNGPAHNNKLFAPVALASGPDGSVYVGDFNFVRRIFPSGNSVSILELRNRDTRHSTSPAHKYYLAMDPMSESLYLSDTNTRKVYKLKSLVETKDLSKNFEVVAGTGDQCLPFDQSHCGDGGKASEASLNSPRGITVDRHGFIYFVDGTMIRRIDENAVITTVIGSNGLTSTQPLSCDSGMDITQVRLEWPTDLAVNPMDNSLYVLDNNIVLQISENRRVRIIAGRPIHCQVPGIDHFLVSKVAIHSTLESARAISVSHSGLLFIAETDERKVNRIQQVTTNGEISIIAGAPTDCDCKIDPNCDCFSGDGGYAKDAKMKAPSSLAVSPDGTLYVADLGNVRIRTISKNQAHLNDMNLYEIASPADQELYQFTVNGTHLHTMNLITRDYVYNFTYNAEGDLGAITSSNGNSVHIRRDAGGMPLWLVVPGGQVYWLTISSNGVLKRVSAQGYNLALMTYPGNTGLLATKSNENGWTTVYEYDPEGHLTNATFPTGEVSSFHSDLEKLTKVALDTSNRENVLMSTNLTATSTIYILKQENTQSTYRVSPDGSLRVTFASGMEINLSSEPHILAGAVNPTLGKCNISLPGEHNANLIEWRQRKEQNKGNVSAFERRLRAHNRNLLSIDFDHMTRTGKIYDDHRKFTLRILYDQTGRPILWSPVSRYNEVNITYSPSGLVTFIQRGTWNEKMEYDQSGKIISRTWADGKIWSYTYLEKSVMLLLHSQRRYIFEYDQSDCLLSVTMPSMVRHSLQTMLSVGYYRNIYTPPDSSTSFIQDYSRDGRLLQTLHLGTGRRVLYKYTKQARLSEILYDTTQVTLTYEESSGVIKTIHLMHDGFICTIRYRQTGPLIGRQIFRFSEEGLVNARFDYSYNNFRVTSMQAVINETPLPIDLYRYVDVSGRTEQFGKFSVINYDLNQVITTTVMKHTKIFNANGQVIEVQYEILKAIAYWMTIQYDNMGRMVICDIRVGVDANITRYFYEYDADGQLQTVSVNDKIQWRYSYDLNGNINLLSHGNSARLTPLRYDLRDRITRLGEIQYKMDEDGFLRQRGNDIFEYNSNGLLQKAYNKVSGWTVQYYYDGLGRRVASKSSLGQHLQFFYADLANPIRVTHLYNHTSAEITSLYYDLQGHLIAMELSSGEEYYVACDNMGTPLAVFSSRGQVIKEILYTPYGDIYHDTYPDFEVIIGFHGGLYDFLTKLVHLGQRDYDVVAGRWTTPNHHIWKQLNLLPKPFNLYSFENNYPVGKIQDVAKYTTDIGTWLELFGFQLHNVLPGFPKPELENMELTYELLQLQTKTQEWDPGKMILGIQCELQKQLRNFISLDQLPMTPQYNEGRCLEGGKQPRFAAVPSVFGKGIKFAIKEGIVTADIIGVANEDSRRLAAILNNAHYLENLHFTIEGRDTHYFIKLGSLEEDLVLIGNTGGRRILENGVNVTVSQMTSVLNGRTRRFADIQLQHGALCFNIRYGTTVEEEKNHVLEMARQRAVAQAWTQEQRRLQEGEEGTRVWTEGEKQQLLGTGRVQGYDGYFVLSVEQYLELSDSANNIHFMRQSEIGRR
What is the function of this protein?
Induces gene transcription activation.
What are the official names of this protein?
Teneurin-1, Ten-1, Protein Odd Oz/ten-m homolog 1, Tenascin-M1, Ten-m1, Teneurin transmembrane protein 1.
What is the protein family that this protein belongs to?
Belongs to the tenascin family. Teneurin subfamily.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Single-pass membrane protein. Note=Colocalizes with isoform 2 at the plasma membrane. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. Cell membrane. Secreted. Note=Transported to the cell membrane and probably secreted to function as an autocrine or paracrine signaling molecule. The lack of a hydrophobic segment sequence suggests that isoform 2 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins. SUBCELLULAR LOCATION: [Ten-1 intracellular domain]: Nucleus. Nucleus speckle. Nucleus matrix. Cytoplasm, cytoskeleton. SUBCELLULAR LOCATION: [Teneurin C-terminal-associated peptide]: Nucleus. Cytoplasm. Cell membrane. Note=Colocalizes with isoform 1 at the plasma membrane. Colocalizes with the dystroglycan complex at the cell membrane in hippocampal cells. Binds hippocampal cell membranes and is incorporated in the cytoplasm by endocytosis in a caveoli-dependent manner. Upon cell internalization is transported arround and in the nucleus.