PharMolix/UniProtQA huggingface dataset:
Protein: LEUC_ACTP7
Sequence: MAKTLYEKLFDAHVVYEAAGETPILYINRHLIHEVTSPQAFDGLRVAGRQVRQIGKTFGTMDHSISTQVRDVNKLEGQAKIQVLELAKNCEANGISLFDMQTKEQGIVHVMGPEQGLTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQARAKSMKVEVRGKVNPGITAKDIVLAIIGKTTMAGGTGHVVEFCGEAIRDLSMEGRMTVCNMAIEFGAKAGLVAPDETTFAYLKGRPHAPKGKDWDDAVEYWKTLKSDDDAVFDSVVVLEAKDIAPQVTWGTNPGQVIGIDQVVPNPQEMADPVTKASAEKALAYIGLDANTDMKNIPVDQVFIGSCTNSRIEDLRAAAAVMKGRKKADNVKRVLVVPGSGLVKEQAEKEGLDKIFIEAGAEWRNPGCSMCLGMNDDRLGEWERCASTSNRNFEGRQGRNGRTHLVSPAMAAAAAMFGKFVDIRHVELN
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: TILS_CYACA
Sequence: MKVTILHQKFIRFVYLLDLELIKRKFVLGLSGGQDSLALLKLLCDYRKTYFGLLKLVYCDHRWRLESIANAQRLYYLSEYSNISFYYFATSTFLSSETQSRTWRYKNLLKISLSFEYSYLLTAHTLSDISETTIYRLVRNLRISEINNLLFTFLYIKKTLSISRPLASVTRNDTYWLCSLSYLPLWSDYTNYWLFLSRNRIRQELFPYLKNYFNCSLERYLDGFIYSNKINLITLNIKLKKILSKIFGYTNDGLYFNVSLFKLLPFFYQHILIRDFHFLFFHNYRSPSQFNRLLFAIALEKSQKVFIRKQYHII
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, chloroplastic, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: EX7L_BACCZ
Sequence: MEKQYLTVTALTRYIKTKIEYDPHLQSVWLKGEISNFKNHSRGHMYFTLKDENARIAAVMFAGHNRNIKFRPENGMKVLVKGKISVYEASGSYQIYIQDMQPDGIGNLHLAYEQLKVRLEEEGLFSQVYKKTIPPYAKTIGVITSPTGAAIRDIITTIKRRYPIGNVIVFPVLVQGESAAPSIVQAIRTANEMEEIDVLIVGRGGGSIEELWAFNEEMVARAIFKSEIPIISAVGHETDFTIADFVADLRAPTPTAAAELAAPNIIELQEKVLQRTLRLQRAMRELVHKKEEKLQVLQKSYAFRYPRQVYEQKEEQLDRALEQLVLAKERYIDKKVNQLKQLSFYLEKHHPSQKIMQTKVAVETLQKQLQREMQTLLQTKEFAFVRAAQKLEALSPLKVMMRGYGLVYDEEKQVLKSVKDVSLGDAVSVQLQDGILDCSVSGIEERELNNGK
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CUTC_ECOK1
Sequence: MALLEICCYSMECALTAQQNGADRVELCAAPKEGGLTPSLGVLKSVRQRVTIPVHPIIRPRGGDFCYSDGEFAAILEDVRTVRELGFPGLVTGVLEVDGNVDMPRMEKIMAAAGPLAVTFHRAFDMCANPLNTLNNLTELGITRVLTSGQKSDALQGLSKIMELIAHRDAPIIMAGAGVRAENLHHFLDAGVLEVHSSAGAWQASPMRYRNQGLSMSSDAHADEYLRYVVDGAAVAEMKGIIERHQAK
What are the official names of this protein?
PF03932 family protein CutC.
What is the protein family that this protein belongs to?
Belongs to the CutC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DED1_NEOFI
Sequence: MADSLKMGNLSLNESQHAPAAPPSNGRAAYIPPHLRQRTMGANVDGAAAPPPPGPAAGAGAWNGPRNAPRGGNWANANASDFSPRAPNVPNGNNSWTPTEAQRRPFDPHAYGHPGHGGSYGGSQGGSAKGSGDGQWRDGKHIPGPANARLERELFGVPNDPTKQSTGINFANYDDIPVEASGHDVPEPVNAFTNPPLDDHLISNIKLARYQTPTPVQKYSIPIVMNGRDLMACAQTGSGKTGGFLFPILSQAFQTGPSAVPAQASGQFGYGRQRKAYPTSLILAPTRELVSQIFDEARKFAYRSWVRPCVVYGGADIGSQLRQIERGCDLLVATPGRLVDLIERGRISLVNIKYLVLDEADRMLDMGFEPQIRRIVEGEDMPNVNERQTLMFSATFPRDIQMLARDFLKDYVFLSVGRVGSTSENITQKVEYVEDHDKRSVLLDILHTHGTSGLTLIFVETKRMADALSDFLLNQRFPATAIHGDRTQRERERALEMFRSGRCPILVATAVAARGLDIPNVTHVINYDLPTDIDDYVHRIGRTGRAGNTGIATAFFNRGNRGVVRELIDLLKEAHQEVPSFLESIAREGSGYGGRGGRGGRGRGGNATRDMRRMGGNVGGGAPSFGGSYGAPSGSSYGGGAGGYGAPPAYGGGYGGGYGGGSYGNPSGPTGPSSWW
What is the function of this protein?
ATP-binding RNA helicase involved in translation initiation.  Remodels RNA in response to ADP and ATP concentrations by facilitating disruption, but also formation of RNA duplexes (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase ded1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX3/DED1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_BRASO
Sequence: MPKRTLQGVVVSDKQAKTVVVRVDRRFTHPIYKKTIRRSKNYHAHDESNEFKPGDMVWIEESKPISKLKRWTVVRGEHKKTA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: RSBW_MYCTO
Sequence: MTDQLEDQTQGGSTVDRSLPGGCMADSDLPTKGRQRGVRAVELNVAARLENLALLRTLVGAIGTFEDLDFDAVADLRLAVDEVCTRLIRSALPDATLRLVVDPRKDEVVVEASAACDTHDVVAPGSFSWHVLTALADDVQTFHDGRQPDVAGSVFGITLTARRAASSR
What is the function of this protein?
A cognate anti-sigma factor for alternative sigma factor SigF.  Alternative sigma factors are held in an inactive form by an anti-sigma factor.  Binds ATP and GTP, may hydrolyze both (By similarity).
What are the official names of this protein?
Anti-sigma-F factor RsbW, Anti-sigma-F factor UsfX, Regulator of SigF, Sigma-F anti-sigma factor RsbW.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-factor family.
Protein: SYD_STRS2
Sequence: MKRSMYAGRVRKEHVGQEITLKGWVGRRRGLGGLIFIDLRDREGIMQLVINPESVEAEVMAKAESLRSEFVIEVTGTVVEREQANDNIPTGAVELQVTSLTVLNTAKTTPFEIKDGIEASDDTRLRYRYLDLRRPEMLNNFKLRAAVTHSIRNYLDDLEFIDVETPMLTKSTPEGARDYLVPSRVSKGHFYALPQSPQITKQLLMNAGFDRYYQIVKCFRDEDLRGDRQPEFTQVDLETSFLNEVEIQDIVEGLIAKVLKDTKGIDVTLPFPRMAYDHAMNFYGSDKPDTRFEMLLQDLTELVKEVDFKVFSEAPVVKAIVVKGAADSYSRKDIDKLTDYAKQFGAKGLAWVKVDKGELAGPVAKFLTGITEKLTASLQLEDKDLVLFVADELEVANNTLGALRNRLAKEQGLIDESKFNFLWIVDWPMFEWSEEEGRYMSAHHPFTLPTEETAHHLDGDLAQVRAVAYDIVLNGYELGGGSLRINQKDMQEQMFKALGFSAEDAHEQFGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEDNIREVIAFPKNNKASDPMTQAPSTVASAQLEELALDITLENE
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGA_NITMU
Sequence: MRTFQEIILALQHYWTRQGCALLQPYDMEVGAGTSHTATFLRALGPEPWKAAYVQPTRRPKDGRYGENPNRLQHYYQFQAVLKPAPSDILELYLGSLEELGFDLRQNDIRFVEDDWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGMNCKPITGEITYGLERLAMYLQGVDNVFDLTWTKGLSYRDVYHQNEVEQSFYNFGHSDLDFLFQAFASHEAQARHLVEQGLPLPAYEQVLKAAHTFNLLDARGAISVTERAAYIGRIRELARSVAHAYYESRKRLGFPLAPVEWTQELLEKAA
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KITH_LISMO
Sequence: MAQLFFRYGSMNSGKTIEILKVAHNYEEQNKTVAIFTSGIDDRDQVGFISSRIGLKREATPIFSDTNIFEIVVNIKPKPNCVLLDESQFLEKEHVFQLAKIVDELNIPVIAYGLKNDFRNELFEGSKYLLLYADKLEEMKTICWFCAKKATMVLRVDDKGKPVYTGEQIMIGGNDHYYPVCRKCHANPPIK
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRCA_PROMM
Sequence: MTEHKRRATPPYHQDPDVTALESLPARQQQVLQATVHHYVDTIEPVGSKTLVQRFGLKASAATVRSAMGALEQRGLLTQPHTSAGRVPSPQGYRHYVDCLLPPPGSAAQHLERELTNLSLRWAALDDLMWQLARRLTDFTGLMSLITRPARPKPTLQAVRLVRSGDRLLVMLVESSNQASHLNLRLPHEASNELEAIEEWTRDQLATTGNGSLDWSSLPPQLNLSGSLLREAIHSHSQAQTPAESDAVFHGMSRLLAQPEFSSSASLQPLLELMDTQPAAVVPVGSEQLGGVWIGAEHPKSALEACSVVQAPYHSSGEGIGQVALVGPMRMAYATAKAAVSSVANHLERLLC
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: OTU7B_HUMAN
Sequence: MTLDMDAVLSDFVRSTGAEPGLARDLLEGKNWDVNAALSDFEQLRQVHAGNLPPSFSEGSGGSRTPEKGFSDREPTRPPRPILQRQDDIVQEKRLSRGISHASSSIVSLARSHVSSNGGGGGSNEHPLEMPICAFQLPDLTVYNEDFRSFIERDLIEQSMLVALEQAGRLNWWVSVDPTSQRLLPLATTGDGNCLLHAASLGMWGFHDRDLMLRKALYALMEKGVEKEALKRRWRWQQTQQNKESGLVYTEDEWQKEWNELIKLASSEPRMHLGTNGANCGGVESSEEPVYESLEEFHVFVLAHVLRRPIVVVADTMLRDSGGEAFAPIPFGGIYLPLEVPASQCHRSPLVLAYDQAHFSALVSMEQKENTKEQAVIPLTDSEYKLLPLHFAVDPGKGWEWGKDDSDNVRLASVILSLEVKLHLLHSYMNVKWIPLSSDAQAPLAQPESPTASAGDEPRSTPESGDSDKESVGSSSTSNEGGRRKEKSKRDREKDKKRADSVANKLGSFGKTLGSKLKKNMGGLMHSKGSKPGGVGTGLGGSSGTETLEKKKKNSLKSWKGGKEEAAGDGPVSEKPPAESVGNGGSKYSQEVMQSLSILRTAMQGEGKFIFVGTLKMGHRHQYQEEMIQRYLSDAEERFLAEQKQKEAERKIMNGGIGGGPPPAKKPEPDAREEQPTGPPAESRAMAFSTGYPGDFTIPRPSGGGVHCQEPRRQLAGGPCVGGLPPYATFPRQCPPGRPYPHQDSIPSLEPGSHSKDGLHRGALLPPPYRVADSYSNGYREPPEPDGWAGGLRGLPPTQTKCKQPNCSFYGHPETNNFCSCCYREELRRREREPDGELLVHRF
What is the function of this protein?
Negative regulator of the non-canonical NF-kappa-B pathway that acts by mediating deubiquitination of TRAF3, an inhibitor of the NF-kappa-B pathway, thereby acting as a negative regulator of B-cell responses.  In response to non-canonical NF-kappa-B stimuli, deubiquitinates 'Lys-48'-linked polyubiquitin chains of TRAF3, preventing TRAF3 proteolysis and over-activation of non-canonical NF-kappa-B.  Negatively regulates mucosal immunity against infections (By similarity).  Deubiquitinates ZAP70, and thereby regulates T cell receptor (TCR) signaling that leads to the activation of NF-kappa-B (PubMed:26903241).  Plays a role in T cell homeostasis and is required for normal T cell responses, including production of IFNG and IL2 (By similarity).  Mediates deubiquitination of EGFR (PubMed:22179831).  Has deubiquitinating activity toward 'Lys-11', 'Lys-48' and 'Lys-63'-linked polyubiquitin chains (PubMed:27732584).  Has a much higher catalytic rate with 'Lys-11'-linked polyubiquitin chains (in vitro); however the physiological significance of these data are unsure (PubMed:27732584).  Hydrolyzes both linear and branched forms of polyubiquitin.
What are the official names of this protein?
OTU domain-containing protein 7B, Cellular zinc finger anti-NF-kappa-B protein, Cezanne, Zinc finger A20 domain-containing protein 1, Zinc finger protein Cezanne.
What is the protein family that this protein belongs to?
Belongs to the peptidase C64 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles be cytoplasm and the nucleus in a XPO1/CRM1-dependent manner.
Protein: MED8A_XENLA
Sequence: MQREEKQLEACLDALISQVSDIKNSLVGFIHKLENEFDRLTWPSVLDSFALLSGQLNTLNKVLKNEKTPLLRNQVIIPLLLSPDRDEEIMRLTEGRVPVFSHEVVPDHLRTKPDPDVEELEKQLSAEAARITTEAAQKQVQSMNKMCSNLLDKISKEERESELGSLRQNKQTFNPTDTNALVAAVAFGKGLSNRRPPGQGGPMAPGQTGASGMLPSAAGMQQVPMSLQSNQQQQHMAGVSMSQGNQPGKMPSSIKTNIKSASMHPYQR
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.  May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 8-A, Mediator complex subunit 8-A.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 8 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPOC_GEODF
Sequence: MEDIFNFFDKPKDPLHFSAIRISVSSPEKIRERSFGEVKKPETINYRTFKPERDGLFCAKIFGPTKDYECNCGKYKRMKHRGIVCEKCGVEVIPSKVRRERLGHIDLATPVAHIWFLKSLPSRIGNLMDITLKDLEKVLYFEAYVVTDPKNTGMPFAQVFSEDQYLKAMEEYNGQFEAGMGAAAIRECLMSMDLDVLAEQLRVEMLEATSEAKRKKTAKRLKVVEAFKSSGNKPEWMILECIPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLMELQAPEVIIRNEKRMLQEAVDALFDNGRRGRAIAGPNKRPLKSLSDMLKGKSGRFRQNLLGKRVDYSGRSVIVVGPELRLHQCGLPKKMALELFKPFIYNKLEEKGFVTTIKSAKKMVEKERPEVWDVLEEVIKEHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCTAFNADFDGDQMAVHLPLSVESQVETRVLMMSTNNILSPAHGKPIIVPSQDMVLGIYYMTREKFFAKGDGKIFASQDEVRIALDADEVDLQARVKVRLKNLATDEKPQLVDTTPGRVVLREILPDEVPFATINKVMTKKELSNLVDVCYRLAGNKETVILADKLKSIGFRYSTIAGISISINDMVIPEGKTAIINRASEDVKEIQNQYTEGLITDGERYNKVIDIWAKSTEEIAKEMLDNLSRDIVHAPDGKEVKVPSFNAIHMMADSGARGSAQQIRQLAGMRGLMAKPSGEIIETPITANFREGLTVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDAIITEPDCGTLDGLVVSSLTEGGEIIEHIGDRILGRVALDDILDPVTGDVLVASNEEIDETLVQKIESAGLEKVKIRSVLTCQSRRGICAKCYGRDLARGHLVNMGEAVGVIAAQSIGEPGTQLTMRTFHIGGTASRRAEQTSLEARTEGSVKFININYVTNTDGHHIVMNRNGELAIVDETGREREKYSILYGAKIKVNVGQVIKQGEAIAEWDPYTMPILTEIAGKVKFGDIIEGVSMEEQVDEVTGLSRKVVVESRDADKRPRITIKDEAGKTAKINETTMGRYYLPVGANITVQEDAVVNAGDVIAKIPRETTKTKDITGGLPRVAELFEARKPKDFAVITEIDGIVTFGKDAKGKRKVIVTPEMGEPKEYLIPKGKHISVHEGDHVRAGEALMDGSSNPHDILRVLGQKELAKYLVDEVQEVYRLQGVKINDKHIETIVRQMLRRVRIKDVGDTTLLIDDQLERYIFEDENERVLDKGGKPAIAEPLLLGITKASLSTESFISAASFQETTKVLTQASIEGKIDGLRGLKENVIMGRLIPAGTGLARYRNLKLVAEEPVVTPSEQVEEVAAG
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: WNT2_BOVIN
Sequence: MNACLVGIWLWLPLLFTWLSPEVSSSWWYMRATSGSSRVMCDNVPGLVSHQRQLCHRHPDVMRAIGLGVTEWTMECQHQFRQHRWNCNTLDRDHSLFGRVLLRSSRESAFVYAISSAGVVFAITRACSQGELKSCSCDPKKKGTAKDNKGTFDWGGCSDNIDYGIKFARAFVDAKERKGKDARALMNLHNNRAGRKAVKRFLKQECKCHGVSGSCTLRTCWLAMADFRKTGNYLWRKYNGAIQVVMNQDGTGFTVANKRFKKPTKNDLVYFENSPDYCIRDRDAGSLGTAGRVCNLTSRGMDSCEVMCCGRGYDTSHITRKTKCECKFHWCCAVRCQDCVEALDVHTCKAPKSPDWAAPT
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity).  Functions as upstream regulator of FGF10 expression.  Plays an important role in embryonic lung development.  May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity).
What are the official names of this protein?
Protein Wnt-2.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Secreted.
Protein: APAH_BORPA
Sequence: MKGSIWTIGDVQGCCAPLAELLAHPEIAGDTDSRFWFAGDLVNRGPQSLAVLRRIMAMGERCTAVLGNHDLHLLAAYAGVRKPSKSDTLDEVLQAPDAVDLIDWLRFRPLAHYEAGHLMVHAGVLAKWDVAKTLALAGEVEQALRGPNWRKALQKMYGNEPATWKDDHTGGKRMRVIINALTRIRLCTPSGHMEFATKVAPGAWPAGLVPWFDVPNRATRDVTVVFGHWSTLGLLMRPDVICLDTGCVWGGALSALRLHDRKLVQVKCKRFQDPNGD
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: Y289_HISS2
Sequence: MAKCKEEVFNWEDEEQEEIIWVSKSEIKRDAEALKKLGEKLVNLTKTNLDKIPLDTGLRDAVELAQRLQKEALRRQIQYIGKLLRAIDPEPIQEALNKIENKHQQQQAKLHKLELLRDELVQKGNSAFTELLIQYPHADRQHLHNLIRSAQKEREQNKPPKSYREIFQYLKDLILED
What are the official names of this protein?
UPF0307 protein HSM_0289.
What is the protein family that this protein belongs to?
Belongs to the UPF0307 family.
Protein: BH047_ARATH
Sequence: MVSKTPSTSSDEANATADERCRKGKVPKRINKAVRERLKREHLNELFIELADTLELNQQNSGKASILCEATRFLKDVFGQIESLRKEHASLLSESSYVTTEKNELKEETSVLETEISKLQNEIEARANQSKPDLNTSPAPEYHHHHYQQQHPERVSQFPGLPIFQGPGFQQSATTLHPPATVLVLPIQPDPQTQDISEMTQAQQPLMFNSSNVSKPCPRYASAADSWSSRLLGERLKASE
What are the official names of this protein?
Transcription factor bHLH47, Basic helix-loop-helix protein 47, AtbHLH47, bHLH 47, Protein POPEYE, Transcription factor EN 139, bHLH transcription factor bHLH047.
What are the subcellular locations of this protein?
Nucleus.
Protein: YL386_MIMIV
Sequence: MGIKGLFKLLREKIKEEEKEGLKRKELGIPDDDTKIKYKPLTVYRFRRLKGITVAIDASLAIYRMVYGKLKSGPSLVNREGKLTSHLRGIFYNVLTFLQNDIIPIYVFDGKAPDIKSKTIEKRKLRKDRFKLTSEDIKEVQILLDLMGIPYIIAPGEADVICSWLCARHDSNGKRYVKGVCTEDSDMLPLGAPYMFKDMLGLNNLNKNIIIVKLKDVLGFLGLTMNEFIDLCVLLGCDYCDNIKGIGPKNAYKLIVEYRTLDKVLEFLHKSNKITSTKTNKTISNNSDDSDNSDDSDNEIKDSNKIDISNDLEDSEENSDDSDSSDEASDSTENEICMLKAAEYFRTALKEIDESKTFVLTDDQLKLRQYQHDELMDFMCVKHNFDPRSIKNGIDRLNSYNKSMNITRPNKKVYHKIIEPKGVTIPSLSDDINFIDSDTDSDTDSDKENNESEKFESKNSRSKTNLIKRNSRS
What is the function of this protein?
Single-stranded DNA endonuclease.
What are the official names of this protein?
Putative endonuclease L386.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
Protein: MARC_ECOL5
Sequence: MLDLFKAIGLGLVVLLPLANPLTTVALFLGLAGNMNSAERNRQSLMASVYVFAIMMVAYYAGQLVMDTFGISIPGLRIAGGLIVAFIGFRMLFPQQKAIDSPEAKSKSEELEDEPSANIAFVPLAMPSTAGPGTIAMIISSASTVRQSSTFADWVLMVAPPLIFFLVAVILWGSLRSSGAIMRLVGKGGIEAISRLMGFLLVCMGVQFIINGILEIIKTYH
What are the official names of this protein?
UPF0056 inner membrane protein MarC.
What is the protein family that this protein belongs to?
Belongs to the UPF0056 (MarC) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: O17B_CONMA
Sequence: CKGKGASCHRTSYDCCTGSCNRGKC
What is the function of this protein?
Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels (Cav).
What are the official names of this protein?
Omega-conotoxin MVIIB, SNX-159.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RT12_OENEH
Sequence: MSGGRWISNLRQVFGRSRASISSSLLPFPPTSISSGFHVPRLLDAWKNPVAAAAAFRLPQSSGFATMNQLIRHGREEKHRSDRKRALGKCPQKQGVCLRVSTRTPKKPNSALGKIAKVRLSNRNDVFAYIPGEGHNLQEHSMVLVRGGRVKDLPGVKFHCIRGVKDLLGIPDRRRGRSKYGAEKPKST
What is the function of this protein?
Protein S12 is involved in the translation initiation step.
What are the official names of this protein?
40S ribosomal protein S12, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MMM1_NEOFI
Sequence: MSSQLNDPTPIPAQSSLSFTQGFLLGQLSVVLLIAAFIKFFIFGEAPPPPSRGLSHRSATHRRSNSIYSSTQHDGNTRTLREKPSNSNVLRPVPSSATNTRSILRKTYYTAIPTNPSSKHGRHRIHHSSHQPESLDWFNVLIAQTIAQYRQTAYLLKDSPTSSILSSLTAALNNPEKKPSFIDKITVTDISLGEEFPIFSNCRIIAVDDPNSDGGRLQALMDVDLSDDNLSIAIETQLLLNYPKPCSAILPVALSISVVRFSGTLCISLVPASTPPLDTPSHSPSPPTAQTTTTGRSKREDQTGGSHSRAGGSSEEPSGENPPKTSPKSNVAFSFLPDYRLDLSVRSLIGSRSRLQDVPKVAQLVEARVHAWFEERVVEPRVQVVGLPDLWPRMGRTGVRTGDDSETGSNAPRSSTAADASGPAHHEDSSREPEVLRFGSLLGTRPPFDLASRTSSFNVETGDLRSRSMTREESSGNLSDQFHMPGSLPGGGVTTT
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  The mdm12-mmm1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The mdm10-mdm12-mmm1 subcomplex further acts in the TOM40-specific pathway after the action of the mdm12-mmm1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Maintenance of mitochondrial morphology protein 1.
What is the protein family that this protein belongs to?
Belongs to the MMM1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: TRI16_MOUSE
Sequence: MAELDLIAPGPLTGVTAHPLAPLGPDPVSAIPVEKEDADPLSKSGEETQEQGHDPAELGAPGEEDQILCDFCLGASRVRAVKSCLTCMVNYCEEHLRPHQENSKLHSHQLTEPAKDQDLRTCPAHHSPLVSFCHTHQQCICQECGEGEHRGDSTVSLDAARRNKEVDLRCMQLDLEQKLKLNENAIARLQANHKSVLVSVSEVKVVAEEKFGELLAAVRKAQADVMVFLEEKEQAALNQVNSIKTHLEHRSLEMEKSKQELERLAAISNTVLFLEEYCKLKKTEDTASPSIYIGLKDKLSGIRKVITDSTLNLIQLLESYKEKLQEFSREEEYDIRTQVSAIVQRKYRTSKPEPRTRDEFLQYACDITFDPDTAHRYLRLQEDNRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVELSGGGTYVGLTCKGIDRKGEERNSCISGNSFSWSIHWNGKEFTAWHSDTETPLKVSPFRRLGIYVNFPGGILSFYGVEYDAMTLIHKFDCKFSEPVYAAFWLSKKENAIRIVDLGEEPEKPAGSSVEAAP
What is the function of this protein?
E3 ubiquitin ligase that plays an essential role in the organization of autophagic response and ubiquitination upon lysosomal and phagosomal damages.  Plays a role in the stress-induced biogenesis and degradation of protein aggresomes by regulating the p62-KEAP1-NRF2 signaling and particularly by modulating the ubiquitination levels and thus stability of NRF2.  Acts as a scaffold protein and facilitates autophagic degradation of protein aggregates by interacting with p62/SQSTM, ATG16L1 and LC3B/MAP1LC3B.  In turn, protects the cell against oxidative stress-induced cell death as a consequence of endomembrane damage.
What are the official names of this protein?
Tripartite motif-containing protein 16, E3 ubiquitin-protein ligase TRIM16, Estrogen-responsive B box protein.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXR_XANOR
Sequence: MAGSSLRQVAVFGATGSIGASALDVIARHPERLRASVLSAGSKVEDLLALCAAHQPAHALIADAALYPALRDGLRALGLATQAHAGAEALDALAGSDACDTVVAAIVGAAGLPSTLAAARAGKRLLLANKESLVLAGELLTRTATAAGAEIIPIDSEHSAIFQCLRSCDAGRGVRRVILTASGGPFRGRDRAGLAAVTPAQAVAHPKWSMGPKISVDSATLMNKGLEVIEAHHLFGLPGEQIDVLVHPQSLVHSLVEFVDGSTLAQLGLPDMRTTLAVGLAWPERVESGVGGLDLLSQGRLDFEAPDTAAFPCLRLAWDALRAGGTAPAILNAANEVAVSAFLQGQVGFLAIPALVEHALTTLPRHNADTLDTLLFADAQARQITERALAHHALHA
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.