PharMolix/UniProtQA huggingface dataset:
Protein: SYC_WOLWR
Sequence: MVRLYNTLTKKKELFIPIDKDHVKMYVCGPTVYDTAHIGNARSVVVYDVLFQLLKFCYGKVTYVRNITDIDDKIINAASEKNSNIESITTYYIKAFHDDMESINCKKPTYEPKATENVDYIIKLIEHLLQSGHAYESDKHVYFNIESYHEYGALSGKKTDELVPGSRVEVNENKKHPGDFVLWKPANDIDYKLSSYWNSPWGEGRPGWHIECSAMSYAYLGKDFDIHGGGIDLQFPHHENEIAQSKSAFAGSMFAKYWMHNGFLTVNEEKMSKSLFNIVKVRDLLDSGIKGEVIRYALLKTHYRKPLDWTENVISDAQETLNKFYRLSRGLDTINIDESNAEISKDFIDALKNDLNIPEALAILHEMAAKINKMSNESEKLKLTESFVKSARFIGLLESSYQEWFTAGVSHQEIERLIDLRRAAKQNKDYNTADKIRDQLKQIGVTISDNEDGTTTW
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPPH_DINSH
Sequence: MTPDDIAALPYRKCVGVVLWDGAGRVFTGQRYDSELPAWQMPQGGIEDGEDARTAALRELVEETGVAVEKVEVLAETPDWIKYDLPPEIVPRIWKGRYKGQAQRWVLMKFLGSDADINIETKHPEFSEWRWLEPASVLDSIVPFKRDVYEQVFDAFSDWL
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: MNMA_YERPP
Sequence: MSDNSQKKVIVGMSGGVDSSVSAYLLQQQGYQVAGLFMKNWEEDDDEEYCSAATDLADAQAVCDKLGMELHTVNFAAEYWDNVFELFLAEYKAGRTPNPDILCNKEIKFKAFLEFAAEDLGADYIATGHYVRRQDVDGKSRLLRGLDGNKDQSYFLYTLSHEQIAQSLFPVGELEKPEVRRIAEQLDLVTAKKKDSTGICFIGERKFRDFLGRYLPAQPGPIMTVDGQLVGKHQGLMYHTLGQRKGLGIGGTKEGGDDPWYVVDKDLDSNTLLVAQGHEHPRLMSVGLVAQQLHWVDRQPVTAPFRCVVKTRYRQQDIPCTVTPLDDERVDVRFDDPVAAVTPGQSAVFYQGEICLGGGIIEQRYPLTNPA
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis.  Sulfur is provided by IscS, via a sulfur-relay system.  Binds ATP and its substrate tRNAs.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HFQ_CLOB6
Sequence: MTKVVNNLQDIFLNGARKNRIPVTIYLTNGFQLKGFVKGFDNFTVILDSDGKQMMIYKHAISTINPAKPLLFVQNPNGDDYKDKE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: SP17_HUMAN
Sequence: MSIPFSNTHYRIPQGFGNLLEGLTREILREQPDNIPAFAAAYFESLLEKREKTNFDPAEWGSKVEDRFYNNHAFEEQEPPEKSDPKQEESQISGKEEETSVTILDSSEEDKEKEEVAAVKIQAAFRGHIAREEAKKMKTNSLQNEEKEENK
What is the function of this protein?
Sperm surface zona pellucida binding protein.  Helps to bind spermatozoa to the zona pellucida with high affinity.  Might function in binding zona pellucida and carbohydrates (By similarity).
What are the official names of this protein?
Sperm surface protein Sp17, Cancer/testis antigen 22, CT22, Sp17-1, Sperm autoantigenic protein 17, Sperm protein 17.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: MATK_TRIFE
Sequence: MEELQLQGYLEKDGSRQQNFLYPLIFQEYIYTLAHDHGLNSSIFYEPMEIVGLGYDNKSSSVLVKRLITQMYQQNSLIYSMNDFNQNRFVGHNNSFYSNFYSQMVSEGFAVIVEIPFSLRLVPSSEEIQIPKSQNLRSIHSIFPFLEDKLSHLNYVLDILIPYPIHLEILVQILQCWIQDVPSLHFLRFFLHEFHNWNNLNLITPTKSISVFSKENKRLFWILYNSYVSEYEFLFVFLRKQSYYLRSTSSRAFLERTHFYVKIEHLIDVCHNHFQKILWFFKDSFMHYVRYKGKAILASRGTYLLIKKWKCYLVNFWQYNFHFWSKPYRIHINPFSNYSFYFLGYISSVLINPSAVKNQMLENFYLVDTLTQKFDTIVPVIPLIGSLSKAKFCTILGHPISKPIWAELSDSDIMDRFGRICRNLSHYHSGSSKKQSLYRIKYILRLSCARTLARKHKSTVRNLLQRLGSGLLEEFFTEEEQVISPIFPKTTLFPLHGSHRERIWYLDIIRINDLANYLDWS
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: WEE2_MOUSE
Sequence: MADTETDQGLNKKLSFSFCEEDTESEGQMTAQDIGGAQSQKPGREESEELEGPVPPTRDELHTSLSRDKESPGPDLWKSVSGPPKCPETPVLHSKSKLPVPTNFSTPKNSLGQPEISLLEKLSSRSSRHMRLTPASLMDEKTSLSLVNINPFTPETYRKLLLQSKGKRKTRDYLEETGEEESKSVQWLPAKRSILQETNMASRYEKEFFEIEKIGVGEFGTVYKCIKRLDGCIYAIKRSAKSFSGLSNELDLHEVYAHAVLGHHPHVVRYYSSWIEDDHVVIQNEYCNGGSLQAAISENTASNNHFQEPKLKDILLQISLGLKYIHNSGMVHLDIKPSNIFICHKMQCDSPVGPEEAESEADWFLNASVMYKIGDLGHATSISKPKVEEGDTRFLANEILQENYQHLPKADIFALGLTIAVAAGAESLPINGDMWHHIRKGNFPEISQELSDDFYGLLKNMIHPAPKERPSAAALARSRILWPFLEKTDELQKQLNLEKSKTATLKRELKKARHIQTPQREVHHCYYQICKGSRHLLVGGRRKAPSSFTRGTSSV
What is the function of this protein?
Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis during both prophase I and metaphase II.  Required to maintain meiotic arrest in oocytes during the germinal vesicle (GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry.  Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation.
What are the official names of this protein?
Wee1-like protein kinase 2, Wee1-like protein kinase 1B, Wee1B kinase, mWee1B.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes mainly in the nucleus. Exported from the nucleus to the cytoplasm before germinal vesicle breakdown (GVBD), allowing meiosis resumption.
Protein: YHY0_YEAST
Sequence: MEMHWITLVAFIATFFNLAATSINNSSLPDVDLTNPLRFFTNIPAGLNFNEVIFLERNGFYLGGIDSPSIYHLINGTAVYFGDVRDNIMPGTVGTTRNVTDVDYGSLLTEYGYEANTDYVSRWIATHVVISPLNATEFFQTPVPVPVPVPITILHQQVNSKLH
What are the official names of this protein?
Uncharacterized protein YHR180W.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PHYIP_HUMAN
Sequence: MELLSTPHSIEINNITCDSFRISWAMEDSDLERVTHYFIDLNKKENKNSNKFKHRDVPTKLVAKAVPLPMTVRGHWFLSPRTEYSVAVQTAVKQSDGEYLVSGWSETVEFCTGDYAKEHLAQLQEKAEQIAGRMLRFSVFYRNHHKEYFQHARTHCGNMLQPYLKDNSGSHGSPTSGMLHGVFFSCNTEFNTGQPPQDSPYGRWRFQIPAQRLFNPSTNLYFADFYCMYTAYHYAILVLAPKGSLGDRFCRDRLPLLDIACNKFLTCSVEDGELVFRHAQDLILEIIYTEPVDLSLGTLGEISGHQLMSLSTADAKKDPSCKTCNISVGR
What is the function of this protein?
Its interaction with PHYH suggests a role in the development of the central system.
What are the official names of this protein?
Phytanoyl-CoA hydroxylase-interacting protein, Phytanoyl-CoA hydroxylase-associated protein 1, PAHX-AP1, PAHXAP1.
What is the protein family that this protein belongs to?
Belongs to the PHYHIP family.
Protein: G7_VAR67
Sequence: MAAEQRRSTIFDIVSKCIVQSVLRDISINSEYIESKAKQLCYCPASKKESVINGIYNCCESNIEIMDKEQLLKILDNLRCHSAHVCNATDFWRLYNSLKRFTHTTAFFNTCKPTILATLNTLITLILSNKLLYAAEMVEYLENQLDSSNKSMSQELAELLEMKYALINLVQYRILPMIIGEPIIVAGFSGKEPISNYSAEVERLMELPVKTDIVNTTYDFLARKGIDTSNNIAEYIAGLKIEEIEKVEKYLPEVISTIANSNIIKNKKSIFPANINDKQIMECSKMLDTSEKYSKGYKTDGAVTSPLTGNNTITTFIPISASDMQKFTILEYLYIMRVMANNVKKKNEGKNNGGVVMHINSPFKVINLPKC
What is the function of this protein?
Late protein which is a part of a large complex required for early virion morphogenesis.  This complex participates in the formation of virosomes and the incorporation of virosomal contents into nascent immature virions (By similarity).
What are the official names of this protein?
Assembly protein G7.
What is the protein family that this protein belongs to?
Belongs to the chordopoxvirinae G7 family.
What are the subcellular locations of this protein?
Host cytoplasm. Virion. Note=Localizes in cytoplasmic virus factories and present in the virion core.
Protein: ANA_DROME
Sequence: MASAMRGEKCERSRIRELVLILSLITMAGDSRATPFDPSFFIEGVQSEVVNPFNRTILNRFNLTEEQILSIQNRSNPNMRDDSAQSSNQQYLQQVATQRLNDIFKRVQKAISNEPNGSASKEKAGFPICNAETTNPEDWSLGNNVTLQFASSVFISNNDDRLSSALLRLYKTNPGQTREHNPGQASTQPISTENPGNTAPNCAEQPPVGPQIRVTVSIVHQQRKKQRKKRTCNTAMLSSSSTGWVEIDVKCALAYWEQQHRQQLRQQQPLQPQLTASVVGILMIEVHDDEENLLRPGLYFAPPTCDQADIAVPWSVYRTEPFKSHLASWTLPRKPRLDIFFNGSNSMKNSYNTPKSRAFIESTTSNSPTIDNQLDESGEYESQQRVHAPLVHHRRHHHNHQQPESESESAQLEAEIEAEELMSSASNSEQQMEPISNHHRHRTGHHHPHHQLHQHHHHHHRHTKHHRIPAHKQE
What is the function of this protein?
Negatively regulates proliferation of neuronal precursor cells, thereby controlling the timing of postembryonic neurogenesis.
What are the official names of this protein?
Protein anachronism.
What are the subcellular locations of this protein?
Secreted.
Protein: RS20_BUCCC
Sequence: MANIKSSKKHISISEKRRKYNCSKRSMIKTFMKKVLFFIKEKNRIKAIKFFYIFQSLVDRYSLKKIIHINKASRYKSVLMNNIKKI
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: CTAA_RHIWR
Sequence: MSILARPAAPSPRPNALANWLLLVAVLVFAIVVVGGITRLTESGLSITEWKPVRGIVPPLNQAEWLAEFENYKRIPQYAAFNLHMTLEGFKAIYFWEYMHRLLARGIGAVLAGVMIVAWWKRAIPAGYGWRMIGIFALGGLQGAIGWWMVYSGLSVRTEVSHIRLATHLIAALLIFSALVWTVLDLRRLARDPDARPARPTALAIAAVLILAVQIMLGAFVAGLRAGYAFATWPKMGDEWFPAGGWNVAQGLANLHENPIVVQFVHRWWAWAAAIAALAVARAARKRGAVGPVHAVATLIVVQIALGIATLLTGVDIAVAVAHQAVAVLLLAALLWAGHGLDKPKVS
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YO268_YEAST
Sequence: MVFVFPFPFFSYGFSSFLEAGKKASYKMYYAEPELKTTRTGRAVACDAGSPRIIRVTLKDKIGLSERFTGRVFCYLAVACAWLSQYYHHTCAFFILYVHVCVCFLFFRWCLFATVSLIHESQTQAGSAYYTK
What are the official names of this protein?
Uncharacterized protein YOR268C.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RS19_PSEMY
Sequence: MPRSLKKGPFIDLHLLKKVEAAVEKNDRKPVKTWSRRSMILPQMVGLTIAVHNGRQHVPVLVNEDMVGHKLGEFAGTRTYRGHVADKKGKR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: RL2_PSYCK
Sequence: MPIVRAKPTSPGRRFVEKVVHPHLYKGRPFAALLESKSKTGGRNNNGRITTRHIGGGHKQHYRIIDFKRTKDNIPATVERIEYDPNRTAHIALLKYADGERRYIIAAKKQAVGDTVMSGELSPIRPGNCLPLKNIPLGTVIHNIELKIGKGAQMARAAGASVQLLGRDGIYAILRLRSGETRRVHVNCRAVIGEVSNTENNLKSLGKAGASRWRGIRPSVRGVAMNPVDHPHGGGEGRNKGRHPTSPWGQKSKGLKTRHNKRTDNMIIRRRAKKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: Y3677_SINFN
Sequence: MKAERPDGRKLRALKRGHLAEYRAALCLIVKGYRIVAMRYRTKLGEIDIIARRGDLIACVEVKARASFDGAVFAVSDTAQRRIRAASDVWLSRQADFHCLSVRYDIVAVMPWRWPRHLPDAF
What are the official names of this protein?
UPF0102 protein NGR_c36770.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: RLMH_PROMA
Sequence: MLNPSRFRILAIGKVRKSWIQNGLEVYRKRLPGLSITEIRDGDIKKESRAIISSIKKDELLIALCEEGEKFTSMDFSHWLQNLGSSRIVFAIGGTNGLSQEVKTSADLCISLSALTFPHEMARLILAEQLYRAISIAKGSPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG108_VACCW
Sequence: MAAAKTPVIVVPVIDRLPSETFPNVHEHINDQKFDDVKDNEVMPEKRNVVVVKDDPDHYKDYAFIQWTGGNIRNDDKYTHFFSGFCNTMCTEETKRNIARHLALWDSNFFTELENKKVEYVVIVENDNVIEDITFLRPVLKAMHDKKIDILQMREIITGNKVKTELVMDKNHAIFTYTGGYDVSLSAYIIRVTTELNIVDEIIKSGGLSSGFYFEIARIENEMKINRQILDNAAKYVEHDPRLVAEHRFENMKPNFWSRIGTAATKRYPGVMYAFTTPLISFFGLFDINVIGLIVILFIMFMLIFNVKSKLLWFLTGTFVTAFI
What is the function of this protein?
Envelope protein that binds to heparan sulfate on the cell surface and might provide virion attachment to target cell.
What are the official names of this protein?
Envelope protein OPG108, Ag35, Virion envelope protein p35.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG108 family.
Protein: RL15_PARD8
Sequence: MNLSNLKPAEGSTKTRKRIGRGPGSGLGGTSTRGHKGAKSRSGYKNKIGFEGGQMPIQRRLPKFGFKNINRVEYKAINIDTLQQMAEAKQLTKIGINELMEAGFISSSQVVKILGNGSLTAKLEVEAHAFSKSAEAAIQAAGGTVVKL
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: FTNB_ECOL6
Sequence: MATAGMLLKLNSQMNREFYASNLYLHLSNWCSEQSLNGTATFLRAQAQSNVTQMMRMFNFMKSVGATPIVKAIDVPGEKLNSLEELFQKTMEEYEQRSSTLAQLADEAKELNDDSTVNFLRDLEKEQQHDGLLLQTILDEVRSAKLAGMCPVQTDQHVLNVVSHQLH
What are the official names of this protein?
Bacterial non-heme ferritin-like protein.
What is the protein family that this protein belongs to?
Belongs to the ferritin family. Prokaryotic subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBL_SALDI
Sequence: SVGFKAGVKEYKLTYYTPEYETKDTDILAAFRVTPQPGVPPEEAGXAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVPGEKDQYXXYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPTAYIKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKSQAETGEIKGHYLNATAGTCEEMMKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMTFRVLRKALRLSGGDHIHAGTVVGKLEGERDITLGFVDLLRDDFVEKDRSRGIYFTQDWVSLPGVIPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVLARNEGRDLAAEGNAIIREACKWSPELAAACEVWKEIKFEFKAVDTLDK
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HOXM_AZOVI
Sequence: MTAPNILILGIGNLLWADEGFGVRCVELLNERYRFPDGVRLMDGGTQGIYLVQHVQQADCLIVFDAVDYGLAPGTLKIVRDDEVPRFMGAKRMSLHQTGFQDVLALAAFSGAYPRELLLIGVQPEELEDFGGSLREPVRAQLEPALRVALEFLAERGVVAAARDGDAERLAPAPLALGRYEAGRPAEELAYRHGDIRFIPQQPLEDD
What is the function of this protein?
Not known.  Could be involved in the processing of hydrogenase.
What are the official names of this protein?
Hydrogenase expression/formation protein HoxM.
What is the protein family that this protein belongs to?
Belongs to the peptidase A31 family.
Protein: ILVC_SYNP2
Sequence: MARMYYDADANLDLLNGKTVAIIGYGSQGHAHALNLKDSGINVVIGLYAGSKSTAKAEAEGLKVLPVAEAAKVADWIMILLPDDVQKSVYTKDILPNLQAGNVLSFAHGFNINFGQIVPPADVDVVMVAPKGPGHLVRRTYEQGQGVPALFAVYQDATGQARDLAMAYAKGIGGTRGGILETTFREETETDLFGEQAVLCGGLSALIKAGFETLVEAGYQPELAYFECLHEVKLIVDLVVEGGLAKMRDSISTTAEYGDYVSGPRVITAETKAAMKEILTEIQTGEFARNFILENQSGQAQFTAIRRREAEHPIEVVGKDLRAMFSWLKES
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: OPA1_MOUSE
Sequence: MWRAGRAAVACEVCQSLVKHSSGIQRNVPLQKLHLVSRSIYRSHHPALKLQRPQLRTPFQQFSSLTHLSLHKLKLSPIKYGYQPRRNFWPARLAARLLKLRYIILGSAVGGGYTAKKTFDEWKDMIPDLSDYKWIVPDFIWEIDEYIDLEKIRKALPSSEDLASLAPDLDKITESLSLLKDFFTAGSPGETAFRATDHGSESDKHYRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQGRLKDTENAIENMIGPDWKKRWMYWKNRTQEQCVHNETKNELEKMLKVNDEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFIDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKVKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK
What is the function of this protein?
Isoforms that contain the alternative exon 4b (present in isoform 2, but not in isoform 1) are required for mitochondrial genome maintenance, possibly by anchoring the mitochondrial nucleoids to the inner mitochondrial membrane.
What are the official names of this protein?
Dynamin-like 120 kDa protein, mitochondrial, Large GTP-binding protein, LargeG, Optic atrophy protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein. Mitochondrion. Mitochondrion membrane. Note=Detected at contact sites between endoplasmic reticulum and mitochondrion membranes.
Protein: ENGB_DESOH
Sequence: MIIRSAEFVISAVQPSQYPDTDLPEIAFAGRSNVGKSSMINLLVNRKNLVKTSSTPGKTRLINFFDINGQLMFVDLPGYGYAKVSRKEQKTWGPMVERYLSSRKTLRGLMLLMDLRREPREDEFLMMQWCAHYDIPWKMVLTKADKFKKTAADRRRHEIARAVGIGADEMILFSTLQKMGRDPALETIARMTGILEE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: UPP_THEMA
Sequence: MKNLVVVDHPLIKHKLTIMRDKNTGPKEFRELLREITLLLAYEATRHLKCEEVEVETPITKTIGYRINDKDIVVVPILRAGLVMADGILELLPNASVGHIGIYRDPETLQAVEYYAKLPPLNDDKEVFLLDPMLATGVSSIKAIEILKENGAKKITLVALIAAPEGVEAVEKKYEDVKIYVAALDERLNDHGYIIPGLGDAGDRLFRTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: ZIPA_HAMD5
Sequence: MQDLRLMLLLFGVITIIVLFLHGVWARRKERSALFYDQKTKDQNQKEDDVLLQILDEEGVGEVKILKKAPPNVEKNAFDKAHHKKIPSQTKYQALKFDSSVACVTASSFAQISETETQLQKKSDDLSHQSKETHHPSIQKEQKVLVLHVAAHSSRNFSGETLLKSILNSHFQFGDMNIFHRYLTLTGERITLFSLANMVKPGFFDLKKMAHFSTPGISIFMTLPCYGHASENFKLMLQSAQKIADELGGLVLDDQRQMITPQKLEDYNALIRSTPHL
What is the function of this protein?
Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring.  Also required for the recruitment to the septal ring of downstream cell division proteins.
What are the official names of this protein?
Cell division protein ZipA.
What is the protein family that this protein belongs to?
Belongs to the ZipA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type I membrane protein. Note=Localizes to the Z ring in an FtsZ-dependent manner.
Protein: MENH_SALTY
Sequence: MMLHAQHMPGQPGTPSLVFLHGFSGDCHEWQPVGEQFHGCSRLYIDLPGHGGSAAIPVDGFADVIRLLRATLISYNILKFWLVGYSLGGRVAMMAACQGIPGLCGLVVEGGHPGLQNEQARAERRLSDGRWAERFRHEPLTEVFHDWYQQPVFASLTAQQRQALTALRSQNNGETLAAMLEATSLAVQPDLREALNALAFPFYYLCGERDSKFRALAQEVAATCHVIRNAGHNAHRENPAGVVDSLAQILRL
What is the function of this protein?
Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
What are the official names of this protein?
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, SHCHC synthase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MenH family.
Protein: PUX4_ARATH
Sequence: MSSKDKKPSKPSSSRGGIRTLSDLNRRSGPDSDSDSDGPQEYYTGGEKSGMLVQDPSKKDDVDEIFNQARQLGAVEGPLEPPPSSRSFTGTGRLLSGENVPTGNQQPEPVVHNIVFWSNGFTIDDGPLRKLDDPENASFLESIRKSECPKELEPADRRAPVHVNLMRKEEKCPERQKRRVSFQGVGRTLGGSNEGSGSSSPVAPDSAPIPIQTEPAPSQSLVIDETVPTTSIQLRLADGTRLVAKFNHHHTVNDIRGFIDSSRPGASLNYQLQTMGFPPKPLTDLTQTIEEAGLANSVVLQKF
What are the official names of this protein?
Plant UBX domain-containing protein 4, PUX4, CDC48-interacting UBX-domain protein 4.