PharMolix/UniProtQA huggingface dataset:
Protein: PROF_VARV
Sequence: MAEWHKIIEDISKNNNFEDAAIVDYKTTKNVLAAIPNRTFAKINPGEVIPLITNHNILKPLIGQKFCIVYTNSLMDENTYAMELLTGYAPVSPIVIARTHTALIFLMGKPTTSRRDVYRTCRDHATRVRATGN
What is the function of this protein?
Participates in either intracellular transport of viral proteins or intercellular spread of the virus.  Cellular profilins modulate actin filament dynamics (polymerization and depolymerization) via direct binding to actin through an actin-binding domain as well as by modulation of other actin-binding proteins.  In contrast to cellular homologs, the poxvirus profilins seem to bind actin only weakly (By similarity).
What are the official names of this protein?
Profilin.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Localizes to inclusion bodies formed by viral A25/ATI protein in the cytoplasm of the host cell.
Protein: CODY_STRA3
Sequence: MPNLLEKTRKITSILQRSVDSLDAELPYNTMAAQLADIIDCNACIINGGGNLLGYAMKYKTNTDRVEEFFETKQFPDYYVKSASRVYDTEANLSVDNDLSIFPVETKENFQDGITTIAPIYGGGMRLGTFIIWRNDKEFSDDDLILVEIASTVVGIQLLNLQTENLEENIRKQTAVTMAINTLSYSEMKAVAAILGELDGLEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLGMKGTYLKVINEGIFDKLKEYN
What is the function of this protein?
DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability.  During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.
What are the official names of this protein?
Global transcriptional regulator CodY.
What is the protein family that this protein belongs to?
Belongs to the CodY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DER_HELMI
Sequence: MAKPIVAIVGRPNVGKSTLFNRLTGGRVAIVEDQPGVTRDRLYRDANWLDREFTVVDTGGLDFGDRENPFSAIIHKQAEAAMEEADVILFLVDGRSGITADDEAVAAILRKAKKPVFLVVNKIEDFSQRERYFDFYSLGLGEPIPISASHGMNTGDLLDAVVAVLPENNGEDDDPDTIKIAVIGRPNVGKSSLVNAILGQERVIVSDIPGTTRDAIDTAFDRDGKRYILIDTAGMRRKGRIEEAVERYSVMRSLRAIDRSDVVLMVIDASQGVTEQDKKIAGYAHEAGKACVLVLNKWDLVPKDDKTMSRFDKVVRSEMSFLAYAPTIYVSALTKQRLPKILELVDFVAEQATRRISTSVLNELLADIQRVTPAPTDRGRRLKILFVTQTAVKPPTFVFFVNDEDLFHFSYRRHVENRFRETFGFEGVPMRFFIREREKEKD
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: TRPF_LEGPH
Sequence: MNPSRIRIKMCGMTRSEDIQYAIDLGVDAIGLIFYPKSVRNVSLEKARIIVNNIPPFVDIVAVLVNPEQSFVQLIINEIPVQLLQFHGEESSEFCRQFNKPFIKAIHPKTAIQIQSAVDEFFDASAILLDTPSDKERGGTGLTFDWNIIPENLSKPYILAGGLNESNILEAITMCHPYAVDVCSGIEASPGVKDHLKMSRFIKAIWG
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: RUVB_AKKM8
Sequence: MGESFYTRTTEAPSSAFDLSLRPPAFSEFCGQEKIKDRLMLMVEAARQRDDVLDHILLSGPPGLGKTTLANIIANAVGCRIHTTSGPQIEKAGDLAGVLTNLEKGDILFIDEIHRLHPAIEEYLYPAMEDFRLDIIIDQGPNARSIQLNLPKFTLVGATTRAGMLTSPLRSRFGLVNRLDYYTREELCAIIERSAGLLNVPVDPEGALQIALRSRGTPRVANSLLRWVRDYAQVRGDGVITEQLAHDALTMIEIDDDGLDEMDKRLLEAMIYKFNGGPVGLSSLAVAVGEDASTLEDVHEPFLIMQGYISRTPRGRVAMPSAYLKMGAAPPANGQGWLL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: OPGC_SHIBS
Sequence: MNPVPAQREYFLDSIRAWLMLLGIPFHISLIYSSHTWHVNSAEPSLWLTLFNDFIHSFRMLVFFVISGYFSYMLFLRYPLKKWWKVRVERVGIPMLTAIPLLTLPQFIMLQYVKGKAESWPGLSLYDKYNTLAWELISHLWFLLVLVVMTTLCVWIFKRIRNNLENSDKTNKKFSMVKLSVIFLCLGIGYAVIRRTIFIVYPPILSNGMFNFIVMQTLFYLPFFILGALAFIFPHLKALFTTPSRGCTLAAALAFVAYLLNQRYGSGDAWMYETESVITMVLGLWMVNVVFSFGHRLLNFQSARVTYFVNASLFIYLVHHPLTLFFGAYITPHITSNWLGFLCGLIFVVGIAIILYEIHLRIPLLKFLFSGKPVVKRENDKAPAR
What is the function of this protein?
Necessary for the succinyl substitution of periplasmic glucans.  Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane.
What are the official names of this protein?
Glucans biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the acyltransferase 3 family. OpgC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YPEL1_HUMAN
Sequence: MVKMTKSKTFQAYLPNCHRTYSCIHCRAHLANHDELISKSFQGSQGRAYLFNSVVNVGCGPAEERVLLTGLHAVADIYCENCKTTLGWKYEHAFESSQKYKEGKFIIELAHMIKDNGWE
What is the function of this protein?
May play a role in epithelioid conversion of fibroblasts.
What are the official names of this protein?
Protein yippee-like 1.
What is the protein family that this protein belongs to?
Belongs to the yippee family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYSC_SHISS
Sequence: MALHDENVVWHSHPVTVQQRELHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFTGIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Adenylyl-sulfate kinase, APS kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
Protein: RECO_ECO5E
Sequence: MEGWQRAFVLHSRPWSETSLMLDVFTEESGRVRLVAKGARSKRSTLKGALQPFTPLLLRFGGRGEVKTLRSAEAVSLALPLSGITLYSGLYINELLSRVLEYETRFSELFFDYLHCIQSLAGVTGTPEPALRRFELALLGHLGYGVNFTHCAGSGEPVDDTMTYRYREEKGFIASVVIDNKTFTGRQLKALNAREFPDADTLRAAKRFTRMALKPYLGGKPLKSRELFRQFMPKRTVKTHYE
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: ATG11_ASHGO
Sequence: MGHVEGNLQLVNAISGRSIGTHVQYFMTMEDLKRFVIQQWHIPGPEIFILQPYGGKFKRGHFQDMVSEAKKAVARGRVRETSVLYVFDRRLFDGGEEALAQATRHDSTTLVRPLVSPLEDAEAEVGERAAASLLTTNLGWLSALEIDVRYFHACIEGWVQQLANMKECLSVLLQYLELYSFDIEKLYHASAEAVDGVRQRCASNDWRQKNQELLETIDAVASRGKLVQFVDLEEMSEAEERLRELERLLSKKLSLFRGALDENHAIRQEIANHIKEVGTRYQDNISNYELEAQILGNFKDMVKKVKEDTRTILDLDTTKVSPDLMTSAVSLFKEMKSTAIPALYTVGLSLFTQASKCMETKASLQREMLVILADIAVAQVNIVDAKNSLLQQVNQDISALHTTEQQLLRVSELPVVYGLYLIELYRRQHWITGLDRYYSEHTKEIQSVLQRELVFREKWSSDFSSYSEIFQWQDDKPQLAKLFSNASPLEVGRPCIDIGTIQTYIEMLARCDVAEDSQTLLKKTLSEVSRFQFIVKSPLAGSVSKDSTDSMNEVIEGYKNRINKLELLLHSTQFSNTSSWPTGVLNSNSLNVFHNNIASINEKLLLSDYKSRDSIMSGKSNEKELQSQLVELQKQLEEAKNEAKRVQQQLKTTKTQLLNGEDERTAYKETLSILNAELSKLILNQEEQKQELVIAAKDFQEKLDVSMRQVNDLLKQVNFWKSKCGDLDKIKQDLLANMATKETDFNNRCTDYERNIVELQRQLSEKCDATNERSVTSTSADVPGETKEYIESLKEVNRRLEEDMFAVFAGNIVLLENIGLLLSRGPDNKLQIIRVKGLRKNIDDSIIKDSSPVINSHMVKSTVFQDVKNLFDELQLSQGVNDQLHFVSELERFYEEDLFQTSVIKRFTDVENLAKKLRKENKAKKSVIERHNKDKITFRDLKVGDLALFLPTRGVAGSLTSSVASSLASSFSSVDLSTPPPPLPTASQSLIKVTPHKPHRNKSTPWAVFTASELGVRYFLKDSEELVKGKDWFVGKIQSMEKYTVNGDSRNPFKLPEGMVWYEVVASCTKEL
What is the function of this protein?
Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy.  Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation.  Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation.  Required for the Cvt vesicles completion (By similarity).
What are the official names of this protein?
Autophagy-related protein 11.
What is the protein family that this protein belongs to?
Belongs to the ATG11 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein. Note=During pexophagy, accumulates in the vacuolar membrane region, where the peroxisomes contact the vacuole.
Protein: MURG_HELP2
Sequence: MKFALTGGGTGGHLSIAKALAIELEKQGVEAIYLGSTYGQDKEWFENSPLFSERYFFNTQGVVNKSFFKKINSLFLQVKAAFKAKEILKKHQITHTISVGGFSAGPASFASLLNHIPLYIHEQNAIKGSLNRYLSPKAKAVFSSYAFKDKGNHVLTSYPVQNAFFDYARTRAEIKHILFLGGSQGAKAINEFALLNAPKLTKQGIKITHICGSDAHEKMRFFYQELGLLDKIELFAFHNNIIEVMRRADLCVSRAGASSVWELCANGLPTIFIPYPFASNNHQYYNVLEFEKENLCYVVPQNELLPKKLFEVIRKLNQKDDQGNKNLTIISAKLQQKIAKDGAKTIIETILSA
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PP418_ARATH
Sequence: MGSKVMMFKWSKNITPSQVIKLMRAEKDVEKSMAVFDSATAEYANGYVHDQSSFGYMVLRLVSANKFKAAEDLIVRMKIENCVVSEDILLSICRGYGRVHRPFDSLRVFHKMKDFDCDPSQKAYVTVLAILVEENQLNLAFKFYKNMREIGLPPTVASLNVLIKALCRNDGTVDAGLKIFLEMPKRGCDPDSYTYGTLISGLCRFGRIDEAKKLFTEMVEKDCAPTVVTYTSLINGLCGSKNVDEAMRYLEEMKSKGIEPNVFTYSSLMDGLCKDGRSLQAMELFEMMMARGCRPNMVTYTTLITGLCKEQKIQEAVELLDRMNLQGLKPDAGLYGKVISGFCAISKFREAANFLDEMILGGITPNRLTWNIHVKTSNEVVRGLCANYPSRAFTLYLSMRSRGISVEVETLESLVKCLCKKGEFQKAVQLVDEIVTDGCIPSKGTWKLLIGHTLDKTIVGEASDTLLRDLDI
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At5g46100.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
Protein: RLA0_TRYCR
Sequence: MPSVSEAKREYEERFNGCLTKYGRVLFCLMDNVRSQQVHDVRRDLRGLGELVMGKKTLQKKIVERRAEDKKASAYDKLLYNTCIEKKLLCGNTALIFTNEEIPVITAVLDKHRVQAPARVGAIAPCDVIVPAGNTGMEPKATSFFQALNIATKIAKGTVEIVSDKKVLSVGDRVDNSTATLLQKLDISPFYYQVEVQSVWDRGMLFLREDLSITDDVVEKYLLEGISNVAALSLGAGIPTAATLPHMIMDAFKTLLGASVATEYEFDEFDGKNLRKAALEGNLGGGVADAAAAADTGAAAAPAAAAEPEEEDDDDDFGMGALF
What is the function of this protein?
Ribosomal protein P0 is the functional equivalent of E. coli protein L10.
What are the official names of this protein?
60S acidic ribosomal protein P0.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: NUFP1_HUMAN
Sequence: MAEPTSDFETPIGWHASPELTPTLGPLSDTAPPRDSWMFWAMLPPPPPPLTSSLPAAGSKPSSESQPPMEAQSLPGAPPPFDAQILPGAQPPFDAQSPLDSQPQPSGQPWNFHASTSWYWRQSSDRFPRHQKSFNPAVKNSYYPRKYDAKFTDFSLPPSRKQKKKKRKEPVFHFFCDTCDRGFKNQEKYDKHMSEHTKCPELDCSFTAHEKIVQFHWRNMHAPGMKKIKLDTPEEIARWREERRKNYPTLANIERKKKLKLEKEKRGAVLTTTQYGKMKGMSRHSQMAKIRSPGKNHKWKNDNSRQRAVTGSGSHLCDLKLEGPPEANADPLGVLINSDSESDKEEKPQHSVIPKEVTPALCSLMSSYGSLSGSESEPEETPIKTEADVLAENQVLDSSAPKSPSQDVKATVRNFSEAKSENRKKSFEKTNPKRKKDYHNYQTLFEPRTHHPYLLEMLLAPDIRHERNVILQCVRYIIKKDFFGLDTNSAKSKDV
What is the function of this protein?
Binds RNA.
What are the official names of this protein?
FMR1-interacting protein NUFIP1, Nuclear FMR1-interacting protein 1, Nuclear FMRP-interacting protein 1.
What are the subcellular locations of this protein?
Nucleus. Note=Distributed in the nucleus in a dot-like pattern.
Protein: HIS7_STAAT
Sequence: MIYQKQRNTAETQLNISISDDQSPSHINTGVGFLNHMLTLFTFHSGLSLNIEAQGDIDVDDHHVTEDIGIVIGQLLLEMIKDKKHFVRYGTMYIPMDETLARVVVDISGRPYLSFNASLSKEKVGTFDTELVEEFFRAVVINARLTTHIDLIRGGNTHHEIEAIFKAFSRALGIALTATDDQRVPSSKGVIE
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y952_BRUME
Sequence: MSDKTPRKPTAFRLEQPARVSAASEQEEPRRPRAVKDLEQITPQADVFDLTDDEAAELEILDPAFEAPERKGWSLSRILFGALGILVSFAIGIWTEDLIRALFARADWLGWTALGVAMVALAAFAAIILRELVALRRLASVQHLRKDAADAAERDDMAAARKAVDALRSIAAGIPETAKGRQLLDSLTDDIIDGRDLIRLAETEILRPLDREARTLVLNASKRVSIVTAISPRALVDIGYVIFESARLIRRLSQLYGGRPGTLGFIKFARRVIAHLAVTGTIAMGDSVMQQLVGHGLASRLSAKLGEGVVNGLMTARIGIAAMDVVRPFPFNAEKRPGIGDFIGDLARLNSDRNARK
What are the official names of this protein?
UPF0283 membrane protein BMEI0952.
What is the protein family that this protein belongs to?
Belongs to the UPF0283 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RM47_HUMAN
Sequence: MAAAGLALLCRRVSSALKSSRSLITPQVPACTGFFLSLLPKSTPNVTSFHQYRLLHTTLSRKGLEEFFDDPKNWGQEKVKSGAAWTCQQLRNKSNEDLHKLWYVLLKERNMLLTLEQEAKRQRLPMPSPERLDKVVDSMDALDKVVQEREDALRLLQTGQERARPGAWRRDIFGRIIWHKFKQWVIPWHLNKRYNRKRFFALPYVDHFLRLEREKRARIKARKENLERKKAKILLKKFPHLAEAQKSSLV
What are the official names of this protein?
39S ribosomal protein L47, mitochondrial, L47mt, MRP-L47, Mitochondrial large ribosomal subunit protein uL29m, Nasopharyngeal carcinoma metastasis-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: EI2BB_YEAST
Sequence: MSSQAFTSVHPNAATSDVNVTIDTFVAKLKRRQVQGSYAIALETLQLLMRFISAARWNHVNDLIEQIRDLGNSLEKAHPTAFSCGNVIRRILAVLRDEVEEDTMSTTVTSTSVAEPLISSMFNLLQKPEQPHQNRKNSSGSSSMKTKTDYRQVAIQGIKDLIDEIKNIDEGIQQIAIDLIHDHEILLTPTPDSKTVLKFLITARERSNRTFTVLVTEGFPNNTKNAHEFAKKLAQHNIETLVVPDSAVFALMSRVGKVIIGTKAVFVNGGTISSNSGVSSVCECAREFRTPVFAVAGLYKLSPLYPFDVEKFVEFGGSQRILPRMDPRKRLDTVNQITDYVPPENIDIYITNVGGFNPSFIYRIAWDNYKQIDVHLDKNKA
What is the function of this protein?
Acts as a regulatory component of the translation initiation factor 2B (eIF2-B or GCD complex), which catalyzes the exchange of eukaryotic initiation factor 2 (eIF-2)-bound GDP for GTP and is regulated by phosphorylated eIF-2.  It activates the synthesis of GCN4 in yeast under amino acid starvation conditions by suppressing the inhibitory effects of multiple AUG codons present in the leader of GCN4 mRNA.  It may promote either repression or activation of GCN4 expression depending on amino acid availability.  GCD6 and GCD7 repress GCN4 expression at the translational level by ensuring that ribosomes which have translated UORF1 will reinitiate at UORF2, -3, or -4 and thus fail to reach the GCN4 start site.
What are the official names of this protein?
Translation initiation factor eIF-2B subunit beta, GCD complex subunit GCD7, Guanine nucleotide exchange factor subunit GCD7, eIF-2B GDP-GTP exchange factor subunit beta.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family.
Protein: BETI_PSEAB
Sequence: MPKVGMQPIRRSQLIHATLEAVDQVGMGDASIALIARLAGVSNGIISHYFQDKNGLLEATMRHLLSALSKAVRERRAALYDDSPRAHLRAIVEGNFDDSQVNGPAMKTWLAFWATSMHQPALRRLQRVNDHRLYSNLCYQFRRQLSADDARAAARGLAALIDGLWLRGALTGDAFDTDEALNIAYDYLDQQLAKQSG
What is the function of this protein?
Repressor involved in the biosynthesis of the osmoprotectant glycine betaine.  It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator BetI.
Protein: ENO_MYCPN
Sequence: MSAQTGTDLFKIADLFAYQVFDSRGFPTVACVVKLASGHTGEAMVPSGASTGEKEAIELRDGDPKAYFGKGVSQAVQNVNQTIAPKLIGLNATDQAAIDALMIQLDGTPNKAKLGANAILAVSLAVAKAAASAQKTSLFKYLANQVMGLNKTEFILTVPMLNVINGGAHADNNIDFQEFMIMPLGANSMHQALKMASETFHALQKLLKQRGLNTNKGDEGGFAPNLKLAEEALDLMVEAIKAAGYQPGSDIAIALDVAASEFYDDTTKRYVFKKGIKAKILDEKEWSLTTAQMIAYLKKLTEQYPIISIEDGLSEHDWEGMETLTKTLGQHIQIVGDDLYCTNPAIAEKGVAHKATNSILIKLNQIGTLTETIKAINIAKDANWSQVISHRSGETEDTTIADLAVAACTGQIKTGSMSRSERIAKYNRLLQIELELGNNAKYLGWNTFKNIKPQKA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: B19_VACCW
Sequence: MSRRLIYVLNINRESTHKIQENEIYTYFSHCNIDHTSTELDFVVKNYDLNRRQPVTGYTALHCYLYNNYFTNDVLKILLNHGVDVTMKTSSGRMPVYILLTRCCNISHDVVIDMIDKDKNHLLHRDYSNLLLEYIKSRYMLLKEEDIDENIVSTLLDKGIDPNFKQDGYTALHYYYLCLAHVYKPGECRKPITIKKAKRIISLFIQHGANLNALDNCGNTPFHLYLSIEMCNNIHMTKMLLTFNPNFEICNNHGLTPILCYITSDYIQHDILVMLIHHYETNVGEMPIDERRIIVFEFIKTYSTRPADSITYLMNRFKNIDIYTRYEGKTLLHVACEYNNTHVIDYLIRINGDINALTDNNKHATQLIIDNKENSPYTINCLLYILRYIVDKNVIRSLVDQLPSLPIFDIKSFEKFISYCILLDDTFYNRHVRNRDSKTYRYAFSKYMSFDKYDGIITKCHKETILLKLSTVLDTTLYAVLRCHNSKKLRRYLTELKKYNNDKSFKIYSNIMNERYLNVYYKDMYVSKVYDKLFPVFTDKNCLLTLLPSEIIYEILYMLTINDLYNISYPPTKV
What are the official names of this protein?
Ankyrin repeat protein B19.
What is the protein family that this protein belongs to?
Belongs to the poxvirinae B18 protein family.
Protein: RS7_GEOMG
Sequence: MPRRREVAKRVILPDPKFNDRVVAKLVNVIMVGGKKSTAERALYGALEVVSQKTGEEAVKVLKKCLDNIKPTLEVKSRRVGGSTYQVPVEVRADRRVSLAMRWLVKYANDRSEKTVTDKLAGEILDVYNNRGAAVKKREDTHRMAEANRAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: GARL_SALEP
Sequence: MNNAIFPNKFKAALAAQQVQIGCWSALASPITTEVLGLAGFDWLVLDGEHAPNDVTTLIPQLMALKGSASAPVVRVPTNEPVIIKRMLDIGFYNFLIPFVETQEEAARAVASTRYPPEGIRGVSVSHRANMFGTVPDYFAQSNKNITIIVQIESQLGVDNVDAIAATEGVDGIFVGPSDLAAALGHLGNASHPDVQQTIQHIFARAKAHGKPCGILAPVEADARRYLEWGATFVAVGSDLGAFRASTQKLADTFKK
What is the function of this protein?
Catalyzes the reversible retro-aldol cleavage of both 5-keto-4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde.
What are the official names of this protein?
5-keto-4-deoxy-D-glucarate aldolase, KDGluc aldolase, KDGlucA, 2-dehydro-3-deoxy-D-glucarate aldolase, 2-keto-3-deoxy-D-glucarate aldolase, 5-dehydro-4-deoxy-D-glucarate aldolase, Alpha-keto-beta-deoxy-D-glucarate aldolase.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily.
Protein: BPT_METPB
Sequence: MTSHPRDTPQFYLTAPSPCPYLPGQEERKVFTHLVGRRARDLNEILTQGGFRRSQTIAYRPACETCRACVSVRVVVEDFAITGSQRRILQRNAGLIGTPEPNRPASEQYALFRRYLDARHGDGGMVDMTVLDYAMMIEDSHVDTHLVVYRERGPDSAIHGRGVGAPVAVCLTDVLADGLSMVYSFYDPEAASRSLGTYMILDHIQRARALGLPYLYLGYWVDGSRKMDYKAKFKPQERLMPQGWVRVE
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GALT_STRT1
Sequence: MAENLVNTFVTQVIENSDYEELDRIYLTNKVFTLVGEGVADVETDSSELIDLKDQLLQAGVKAGSVGELNEEQDIIGAQLMDLITPRPSVVNRNFWDTYKSNPEQAIADFYAQSKRNDYVKVKAIAQNIAYKAPTKYGDLEITINLSKPEKDPKAIAAAKNAVASDYPKCQLCMENEGYLGRINHPARSNHRVVRFQMEDKEWGFQYSPYAYFNEHSIFFYGKHEPMHISPLTFGRLLTIVEAFPGYFAGSNADLPIVGGSILTHEHYQGGRHTFPMEVAGIKEKVSFDGYSDVEAGIVNWPMSVLRLRSEDKERLIALATKILNCWRGYSDEKAGVLAESDGQPHHTITPIARRKDGKFELDLVLRDNQTSEEYPDGIYHPHKDVQHIKKENIGLIEVMGLAILPPRLKTELKDVEDYLLGQGNQVAPIHQEWADELKAQNPNITAEEVTEVVRQSVADIFARVLEDAGVYKTNSEGLDQFKAFVDFVNLAD
What are the official names of this protein?
Galactose-1-phosphate uridylyltransferase, Gal-1-P uridylyltransferase, UDP-glucose--hexose-1-phosphate uridylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IBB1_ARAHY
Sequence: EASSSSDDNVCCNGCLCDRRAPPYFECVCVDTFDHCPASCNSCVCTRSNPPQCRCTDKTQGRCPVTECRS
What is the function of this protein?
These proteins inhibit trypsin and chymotrypsin, having 2 sites of interaction with trypsin.  The site of interaction with chymotrypsin has not been determined but is not independent of the trypsin-reactive sites.
What are the official names of this protein?
Bowman-Birk type proteinase inhibitor A-II.
What is the protein family that this protein belongs to?
Belongs to the Bowman-Birk serine protease inhibitor family.
Protein: HGD_BORPD
Sequence: MPLQYQSGFGNDWATEALPGALPAGRNSPQRCPYGLYAEQLSGTAFTAPRAENRRSWLYRIRPAAQHRPFEPFDGAARWLSDFGAAPVTPNQLRWSPLPLPDAPTDFIEGVQTWGGNGGPGEHGGVGIHLYAANRSMQGRYFYNADGELLIVPQQGRLRLATELGIIEVEPLEIAVIPRGVRLRVDLPDGQARGYMLENFGAALHLPELGPIGSNCLANARDFQTPVACYEDIEGDFELIAKFTGGFWRAAIGHSPLDVVAWHGTHAPYKYDLRHFNTIGSISFDHPDPSIFTVLTSPSDTPGTANMDFAIFPPRVLAMENTFRPPWFHRNVASEFMGLIHGVYDAKAEGFAPGGASLHNCMSGHGPDADTFEKATAADTSQAHYIRDTMAFMFETRRVIRPTAQALASAQLQSDYYECWQGLNKHFDPAQP
What is the function of this protein?
Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine.  Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
What are the official names of this protein?
Homogentisate 1,2-dioxygenase, HGDO, Homogentisate oxygenase, Homogentisic acid oxidase, Homogentisicase.
What is the protein family that this protein belongs to?
Belongs to the homogentisate dioxygenase family.
Protein: RBN_ECO57
Sequence: MELIFLGTSAGVPTRTRNVTAILLNLQHPTQSGLWLFDCGEGTQHQLLHTAFNPGKLDKIFISHLHGDHLFGLPGLLCSRSMSGIIQPLTIYGPQGIREFVETALRISGSWTDYPLEIVEIGAGEILDDGLRKVTAYPMEHPLECYGYRIEEHDKPGALNAQALKAAGVPPSPLFQELKAGKTIMLEDGRQINGADYLAAPVPGKALAIFGDTGPCDAALDLAKGVDVMVHEATLDITMEAKANSRGHSSTRQAATLAREAGVGKLIITHVSSRYDDKGCQHLLRECRSIFPATELANDFTVFNV
What is the function of this protein?
Zinc phosphodiesterase, which has both exoribonuclease and endoribonuclease activities.
What are the official names of this protein?
Ribonuclease BN, RNase BN, Ribonuclease Z homolog, RNase Z homolog.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family. RNase BN subfamily.