PharMolix/UniProtQA huggingface dataset:
Protein: SIA7B_MOUSE
Sequence: MDLPRRWLFRMLLLVATSSGILLMLYSSAGQQSPETQVPARNMAYPRAFFDPKPPNSENRKSRLCQHSLSLAIQKDRRFRSLFDLSTPVLLWEGLFTQELWNNLSQHKVPYGWQGLSHEVIASTLRLLKSPESGELFGAPRKLPLSCIRCAVVGNGGILNGSRQGQKIDAHDYVFRLNGAITEGFERDVGTKTSFYGFTVNTMKNSLISYAKLGFTSVPQGQNLRYIFIPSSIRDYLMLRSAILGVPVPEGPDKGDRPHTYFGPETSASKFKLLHPDFISYLTERFLKSKLINTRFGDMYMPSTGALMLLTALHTCDQVSAYGFITNNYQKYSDHYFEREKKPLIFYANHDLSLEASLWRDLHNAGILWLYQR
What is the function of this protein?
Catalyzes the transfer of N-acetylneuraminyl groups onto glycan chains in glycoproteins (PubMed:8662927).  Shows a preference for N-acetylgalactosamine (GalNAc) residues already modified by the addition of galactose or galactose followed by sialic acid in alpha-2,3 linkage (PubMed:8662927).
What are the official names of this protein?
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2, Gal-beta-1,3-GalNAc alpha-2,6-sialyltransferase, GalNAc alpha-2,6-sialyltransferase II, ST6GalNAc II, ST6GalNAcII, Sialyltransferase 7B, SIAT7-B.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 29 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: KITH_SUHVN
Sequence: MRILRIYLDGAYDTGKSTTARVMALGGALYVPEPMAYWRTLFDTDTVAGIYDAQTRKQNGSLSEEDAALVTAHDQAAFATPYLLLHTRLVPLFGPAVEGPPEMTVVFDRHPVAATVCFPLARFIVGDISAAAFVGLAATLPGEPPGGNLVVASLDPDEHLRRLRARARAGEHVDARLLTALRNVYAMLVNTSRYLSSGRRWRDDWGRAPRFDQTTRDCLALNELCRPRDDPELQDTLFGAYKAPELCDRRGRPLEVHAWAMDALVAKLLPLRVSTVDLGPSPRVCAAAVAAQTRGMEVTESAYGDHIRQCVCAFTSEMGV
What is the function of this protein?
Catalyzes the transfer of the gamma-phospho group of ATP to thymidine to generate dTMP in the salvage pathway of pyrimidine synthesis.  The dTMP serves as a substrate for DNA polymerase during viral DNA replication.  Allows the virus to be reactivated and to grow in non-proliferative cells lacking a high concentration of phosphorylated nucleic acid precursors.
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae thymidine kinase family.
Protein: ESR2_ARATH
Sequence: MEEAIMRLEGAEHRETNIHSLKRKPSRTSSTAPGSPGGVTTAKAASGAGASGVSTIRYRGVRRRPWGRYAAEIRDPLSKERRWLGTFDTAEEAACAYDCAARAMRGLKARTNFVYPMPSLDSYHHRIFSSPPMNMFLLRDVLNSQSLSPLTTFAYPPCNLSNVNDVVHESFTNVNDVCEDLSPKAKRSSTIENESLISNIFEPEPASSGLLQEIVQGFLPKPISQHASIPPKSNQQSVGVFPTMPESGFQTDVRLADFHVEGNGFGQVKYHGELGWADHENGFDSAKMQQNGNGGMFYQYCFHDDY
What is the function of this protein?
Required for correct embryo patterning and cotyledon organogenesis.  May regulate positively the gibberellin signaling pathway leading to germination, hypocotyl elongation, and leaf expansion.  Involved in the cytokinin signaling pathway that promotes shoot regeneration, probably through transcriptional activation of target genes such as CUC1.  Acts as a transcriptional activator.  Binds to the GCC-box pathogenesis-related promoter element.  May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
What are the official names of this protein?
Ethylene-responsive transcription factor ESR2, Protein DORNROESCHEN-LIKE, Protein DRN-LIKE, Protein ENHANCER OF SHOOT REGENERATION 2, Protein SUPPRESSOR OF PHYTOCHROMEB 2.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: HV2B_RABIT
Sequence: QSVKESEGGLFKPTDTLTLTCTVSGFSLSGYDMSWVRQAPGKGLEWIGVIYASGSTYYATWAKSRSTITRTSBTVBLMDSLTAQDTATYFCARGHTGLSYLKSSVDVWGPGTLVTVS
What are the official names of this protein?
Ig heavy chain V-A2 region K-25.
Protein: AROE_METBU
Sequence: MKKIFAVLGDPIEHSLSPIMHNSAFEALDMDCTYHAFRVEKNDLENALQGAKAMGFGGLNLTVPLKETALKFVDADSLAAKIGAINTIDFKDGIKGYNTDGIGAKRTIEDEGVDIKDKNVLILGAGGAARAIAFTFAEAGANVNIANRTPERAMQLAAEIGDAKGYGLDIVDNGLEDIDILINTTTVGLGNSNGTLVTAEQMHSDLAVFDIVYNPLMTKLLQEAETAGARPITGIMMLVYQGAEAFRIWTGKEPPINVMKKTVMETLDI
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: LOLD_YERPS
Sequence: MSNHPLLQCINLCKRYQEGQLHTDVLRNVSFAIEPGELMAIVGSSGSGKSTLLHLLGGLDSPTSGEVIYQGRSLNQLSSTAKAELRNRELGFIYQFHHLLPDFTALENVAMPLLIGGSKPAEAQEKAHEMLAAVGLAKRSKHRPSELSGGERQRVAIARSLVNNPSLVLADEPTGNLDQRNADSIFNLLGELNVRQGTAFLVVTHDLQLAKRMSRQLEMRDGQLQHHLTLVGAE
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TMC2A_DANRE
Sequence: MPKKSDTTRKLEDVGIEIDGDVDSAEEDKKSKGKGGKKAAGGKRGKASEDGEDEDEDDKPPKGRRAANKKKPAPVDEEDSDDDIPQRRSAGNRRRGNVRERGDGDKKKSGKKGRRGGKKNEKGKGKDSDKDSDKDEKKKKNSSGDESDSDEEDESMSEGEMAKLMEEVEEKKKLIANIRNKPWRMRRRLKVLKEAQQFVDKFEGALGKGKGRKLYAYKVMMMKKWIKFKRDFENFRTACIPWERKIKEVESHFGSSVASYFIFLRWMYGMNLVLFSLTFGLVVIPEVLMGLPYGSIPRKTVPREDQDTAMDYSVLTDFNGYCKYSVLFYGYYNNQRTIGFLKFRLPLSYLMVGIGTFGYSLMVVIRTMAKNADVGGGDGEDNEFTFAWKMFTSWDYLIGNAETADNKYASITTSFKESIVDEQENQKDENIHLRRFLRVLANFLITCTLGGSGYLIYFVVKRSQEFQNMDNLSWYEKNELEIIMSLLGLVGPMLFETIAELEEYHPRIALKWQLGRIFALFLGNLYTFLLALFDEVNAKLEEEESIKNASIWFLKEYYANYTANNPNDTGTPPPINPADAIRGPCWETTVGVEFVKLTISDIQVTYLTILIGDFLRAFIVRFLNYCWCWDLEAGWPSYGEFDISGNVLGLVFNQGMIWMGAFYAPGLVGINVLRLLSSMYYQCWAVMACNVPHERVFKASKSNNFYMGLLLLILFLSLLPVVYTIMSLPPSFDCGPFSGKERMFDVVMETIDLDLPAFMGTLFGYVANPGLVISAVLLMVLAIYYLNSVSEAYKNSNNELKKKMQMARDEEKNRRNNKDSTNQVMKDLEDLLPNRPPTPPSPRENIAEKNQGQGGKSAKVKPGTAGGVHLQKDVSLASANPNARGPVTRAPGPRGPGPLPGQPGAGRGQGPPPRRQ
What is the function of this protein?
Probable ion channel required for the normal function of hair cells (By similarity).  Component of the hair cell's mechanotransduction (MET) machinery.  Involved in mechanosensitive responses of the hair cells (PubMed:25114259).
What are the official names of this protein?
Transmembrane channel-like protein 2-A.
What is the protein family that this protein belongs to?
Belongs to the TMC family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Localized to mature hair bundles of the hair cells.
Protein: RL20_VIBAN
Sequence: MPRVKRGVQARARHKKVLKQAKGYYGARSRVYRVAFQAVTKAGQYAYRARRTKKRQFRQLWIARINAASRQNGLSYSRFINGLKKASIEIDRKILADIAVFDKAAFAVLVEKAKTAL
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: TRGV3_HUMAN
Sequence: MRWALLVLLAFLSPASQKSSNLEGRTKSVTRQTGSSAEITCDLTVTNTFYIHWYLHQEGKAPQRLLYYDVSTARDVLESGLSPGKYYTHTPRRWSWILRLQNLIENDSGVYYCATWDR
What is the function of this protein?
V region of the variable domain of T cell receptor (TR) gamma chain that participates in the antigen recognition (PubMed:24600447).  Gamma-delta TRs recognize a variety of self and foreign non-peptide antigens frequently expressed at the epithelial boundaries between the host and external environment, including endogenous lipids presented by MH-like protein CD1D and phosphoantigens presented by butyrophilin-like molecule BTN3A1.  Upon antigen recognition induces rapid, innate-like immune responses involved in pathogen clearance and tissue repair (PubMed:23348415, PubMed:28920588).  Binding of gamma-delta TR complex to antigen triggers phosphorylation of immunoreceptor tyrosine-based activation motifs (ITAMs) in the CD3 chains by the LCK and FYN kinases, allowing the recruitment, phosphorylation, and activation of ZAP70 that facilitates phosphorylation of the scaffolding proteins LCP2 and LAT.  This lead to the formation of a supramolecular signalosome that recruits the phospholipase PLCG1, resulting in calcium mobilization and ERK activation, ultimately leading to T cell expansion and differentiation into effector cells (PubMed:25674089).  Gamma-delta TRs are produced through somatic rearrangement of a limited repertoire of variable (V), diversity (D), and joining (J) genes.  The potential diversity of gamma-delta TRs is conferred by the unique ability to rearrange (D) genes in tandem and to utilize all three reading frames.  The combinatorial diversity is considerably increased by the sequence exonuclease trimming and random nucleotide (N) region additions which occur during the V-(D)-J rearrangements (PubMed:24387714).
What are the official names of this protein?
T cell receptor gamma variable 3, T-cell receptor gamma V-gamma-1.1 region.
What are the subcellular locations of this protein?
Cell membrane.
Protein: ARP2A_DANRE
Sequence: MDSQGKKVVVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTAKVGNIEIKDLMVGDEASELRSMLEVNYPMENGIVRNWDDMKHLWDYTFGPEKLNIDSRNCKILLTEPPMNPTKNREKIIEVMFETYQFSGVYIAIQAVLTLYAQGLLTGVVVDSGDGVTHICPVYEGFSLPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMMKEKLCYVGYNIEQEQKLALETTVLVESYTLPDGRVIKVGGERFGAPEALFQPHLINVEGVGVAELLFNTIQAADIDTRAEFYKHIVLSGGSTMYPGLPSRLERELKQLYLERVLKGDVDKLSKFKIRIEDPPRRKHMVFLGGAVLADIMKDKDNFWMTREEYQEKGTRVLEKLGVTVR
What is the function of this protein?
ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (By similarity).  The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (By similarity).  Seems to contact the pointed end of the daughter actin filament (By similarity).  In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (By similarity).  The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) (By similarity).
What are the official names of this protein?
Actin-related protein 2-A, Actin-like protein 2-A.
What is the protein family that this protein belongs to?
Belongs to the actin family. ARP2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection. Nucleus.
Protein: LIGB_SALG2
Sequence: MRLWKSMAWGILLWHSQSGALCPAWPPARAAEEITRLQQQLADWNDIYWKQGVSAVDDSVYDQLSARLVQWQRCVGQDVSSTPVSPPLNGTTMHPVAHTGVRKLADRQAVEQWMRGRSELWVQPKVDGVAVTLVYQNGKLTRAISRGNGLQGEDWTPKIRLIPSIPQTTQGALANAVLQGEIFLQREGHIQQRMGGMNARSKVAGMLMRQDNASALNSLGIFIWAWPDGPANMPERLSQLAKAGFSLTNKYTLAVKDASEVERARQSWLTSALPFVTDGVVIRMAKEPASQHWRPGQGDWLAAWKYPPVAQVAQVSAIQFSVGKSGKITVVASLVPVILDDKRVQRVNIDSVKRWEAWDIAPGDQILVSLAGQGIPRLDEVVWRSRERSKPVPPDSHFNSLTCFYASETCQEQFISRLVWLGSRSALGLDGMGEASWRALHQTHRFKHIFSWLALTSAQIANTPGFAKGKSEQIWRQFNLARRQSFTRWIMAMDIPLTQAALQASGDRSWEQLLMRTEQHWWQLPATGERRAGRVIDWRNNPQIKTLSRWLAAQHIPGFGS
What is the function of this protein?
Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.
What are the official names of this protein?
DNA ligase B, Polydeoxyribonucleotide synthase [NAD(+)] B.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigB subfamily.
Protein: CREA_ASPFU
Sequence: MPPPASSMGFSDLLNPQNPESTPSTPASKSSAPSTPSTEQSNSNMASSVSLLPPLMKGARPANEEPRQDLPRPYKCPLCDRAFHRLEHQTRHIRTHTGEKPHACQFPGCTKRFSRSDELTRHSRIHNNPNSRRNNKAQHLAAAAAAAAANQDNALASNAASMMPPPSKPITRSAPVSQVGSPDISPPHSFSNYAGHMRSNLGSYARNSDRASSGMDINLLATAASQVERDEHYGFHNGPRGHHIFGSRHHNNNRLPSLSAYAISQNMSRSHSHDEDDMYSHRVKRSRPNSPNSTAPSSPTFSHDSLSPTPDHTPLATPAHSPRLRPLGTSELQLPSIRHLSLHHTPALAPMEPQPEGPNYYSPTQPHVGPSISDIMSKPDGTQRKLPVPQVPKVAVQDLLSPGFTSVSSSASNSVAGGDLADRF
What is the function of this protein?
Transcription regulator component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB.  Represses the transcription of the alcR, alcA and aldA genes by binding to a GC-rich region in their promoter.  Also plays a role in response to carbon starvation and the control of extracellular proteases activity (By similarity).
What are the official names of this protein?
Probable DNA-binding protein creA, Carbon catabolite repressor A.
What is the protein family that this protein belongs to?
Belongs to the creA/MIG C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARCC1_STAAR
Sequence: MAKIVVALGGNALGKSPQEQLKLVKNTAKSLVGLITKGHEIVISHGNGPQVGSINLGLNYAAEHNQGPAFPFAECGAMSQAYIGYQLQESLQNELHSIGMDKQVVTLVTQVEVDENDPAFNNPSKPIGLFYNKEEAEQIQKEKGFTFVEDAGRGYRRVVPSPQPISIIELESIKTLIKNDTLVIAAGGGGIPVIREQHDGFKGIDAVIDKDKTSALLGANIQCDQLIILTAIDYVYINFNTENQQPLKTTNVDELKRYIDENQFAKGSMLPKIEAAISFIENNPKGSVLITSLNELDAALEGKVGTVIKK
What are the official names of this protein?
Carbamate kinase 1.
What is the protein family that this protein belongs to?
Belongs to the carbamate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGC_ANADE
Sequence: MAKLLAMILAGGEGRRLDPLTRDRAKPAVPFGGRYRIVDFVLSNMANSGILKMKVVVQYKSESLNTHVQRAWRLTSLLNQYVELVPAQMRVGPKWFEGSADAIYQNLNIITDEEPDFTFVFGADHVYRMDARQMLAFHQDRKADLTVAAVPIPVGEASEFGIIEVDAEGRMVGFVEKPTSDPKTMPGDPTRCLASMGNYLFTTEALVQEIVRDAGDPASAHDFGKSIVASMYQRKRVYVYDFARNVVPGQTERERGYWRDVGSIDAYFQANMDLVAVDPVFSLYNDEWPIFTVQYNYPPAKFVFNNERDNRIGRATDSLISEGCIISGAHVHHSILSPKVRVNSYATVEESIVFENVNIGRHCRIRRAIIDKHVDIPAHTTIGFDHEKDRKHFHVTESGIVIIPKGMRIEAGR
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: PANCY_SYNS9
Sequence: MPTMGALHAGHGTVIRAASAMGPVLVSVFVNPLQFGPDEDLARYPRSLESDLVVAERWGAAALWAPSVEQIYPQGGERHPSTIQVPPGLQKHLCGAARPGHFDGVVTVVARLLDLVRPRQLWLGEKDWQQLVILRWLVAHLARPVIVQGVATVREADGLALSSRNQYLSPDQRRMAAALPEALHAARGDGSDPIPALRGSLSDAGFEVEYVQRVDPCTLQPCGDETAISLLAAAVRCGSTRLIDHAFLMTRQPLVAIDGPAGAGKSTVTRAFAERLGLVYLDTGAMYRSVTWLVLERGVNPSDGVAIEPLLKDLDVQLQSLPGGVQQVLVNGEDVSSAIRSPDVTASVSAVAAHRCVRQALTVQQKSMGSKGGLVAEGRDIGTAVFPHADLKVFLTATVTERARRRALDLEQRGFAVPERAELEAQIAERDRLDSTREEAPLMQADDAIELVTDGMDIDAVIEALVRLFRERVAEEAWPTPQR
What is the function of this protein?
Catalyzes the transfer of a phosphate group from ATP to either CMP or dCMP to form CDP or dCDP and ADP, respectively.
What are the official names of this protein?
Bifunctional pantoate ligase/cytidylate kinase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROK_CHLL2
Sequence: MKHHSLIFLTGFSGSGKSTIGPLLANSLGYGFIDLDQEIESKAGKSITKIFAEEGEQTFRNLELETLRQLTGKKELVVSLGGGVLENNDCYRLIRENGTLVYLKSSPRSLARRLCNKTDRPLLKGEHGTRLSREEIELKISTILEKREPRYATADLSVQTDIKRIGSTVEELTRTIIRFVRQAEQARLKQQSDNNREKQ
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBC9_MOUSE
Sequence: MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFAPS
What is the function of this protein?
Accepts the ubiquitin-like proteins SUMO1, SUMO2 and SUMO3 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2, CBX4 and ZNF451.  Can catalyze the formation of poly-SUMO chains.  Essential for nuclear architecture, chromosome segregation and embryonic viability.  Necessary for sumoylation of FOXL2 and KAT5 (By similarity).  Sumoylates p53/TP53 at 'Lys-386'.  Mediates sumoylation of ERCC6 which is essential for its transcription-coupled nucleotide excision repair activity (By similarity).
What are the official names of this protein?
SUMO-conjugating enzyme UBC9, RING-type E3 SUMO transferase UBC9, SUMO-protein ligase, Ubiquitin carrier protein 9, mUBC9, Ubiquitin carrier protein I, Ubiquitin-conjugating enzyme E2 I, Ubiquitin-protein ligase I.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Mainly nuclear (PubMed:18681895). In spermatocytes, localizes in synaptonemal complexes (By similarity). Recruited by BCL11A into the nuclear body (PubMed:18681895).
Protein: DNAK_STRA3
Sequence: MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKNGEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAEDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGMDKTDKDEKILVFDLGGGTFDVSILELGDGVFDVLATAGDNKLGGDDFDQKIIDFLVEEFKKENGIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFITAGSAGPLHLEMSLSRAKFDDLTRDLVERTKTPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKSVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSKSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDKNGIVSVKAKDLGTQKEQHIVIQSNSGLTDEEIDKMMKDAEANAEADAKRKEEVDLKNEVDQAIFATEKTIKETEGKGFDTERDAAQSALDELKKAQESGNLDDMKAKLEALNEKAQALAVKLYEQAAAAQQAAQGAEGAQSADSSSKGDDVVDGEFTEK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: V_SENDF
Sequence: MDQDAFILKEDSEVEREAPGGRESLSDVIGFLDAVLSSEPTDIGGDRSWLHNTINTPQGPGSAHRAKSEGEGEVSTPSTQDNRSGEESRVSGRTSKPEAEAHAGNLDKQNIHRAFGGRTGTNSVSQDLGDGGDSGILENPPNERGYPRSGIEDENREMAAHPDKRGEDQAEGLPEEVRGGTSLPDEGEGGASNNGRSMEPGSSHSARVTGVLVIPSPELEEAVLRRNKRRPTNSGSKPLTPATVPGTRSPPLNRYNSTGSPPGKPPSTQDEHINSGDTPAVRVKDRKPPIGTRSVSDCPANGRPIHPGLETDSTKKGHRREHIIYERDGYIVDESWCNPVCSRIRVIPRRELCVCKTCPKVCKLCRDDIQCMRPDPFCREIFRS
What is the function of this protein?
Plays an essential role in the inhibition of host immune response.  Prevents the establishment of cellular antiviral state by blocking interferon-alpha/beta (IFN-alpha/beta) production and signaling pathway.  Interacts with host IFIH1/MDA5 and DHX58/LGP2 to inhibit the transduction pathway involved in the activation of IFN-beta promoter, thus protecting the virus against cell antiviral state.  Interacts also with and inhibits host IRF3 (By similarity).
What are the official names of this protein?
Protein V.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses V protein family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: RS5_BIFLO
Sequence: MAEETQNTVATESNNEDRKGRRGQRGEGRRGERRNRREENHGDELLDRVVTINRVSKTHKGGRTFSFAALVVVGDGNGTVGVGYGKSREVPAAIAKGQLDAKKHMFSVPRVRGTITHPVQGHDAAGTVLLRPAAPGTGVIAGGSVRAVMECAGITDVLTKSMGSATAVNVVRATVDALKQLEEPEEIAARRGLALDEVAPDALLRARAAGIAEARKAREEAAAAKAAEEKDGE
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: MDH_METC4
Sequence: MARSKIALIGAGQIGGTLAHLAGLKELGDVVLFDIVDGVPQGKALDIAESAPVDGFDAKYSGASDYSAIAGADVVIVTAGVPRKPGMSRDDLIGINLKVMEAVGAGIKEHAPDAFVICITNPLDAMVWALQKFSGLPTNKVVGMAGVLDSARFRHFLAEEFGVSVEDVTAFVLGGHGDDMVPLTRYSTVAGVPLTDLVKLGWTTQEKLDAMVERTRKGGGEIVNLLKTGSAFYAPAASAIAMAESYLRDKKRVLPCAAYLDGQYGIDGLYVGVPVVIGENGVERVLEVTFNDDEKAMFEKSVNSVKGLIEACKSVNDKLA
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: ISPG_ACIF5
Sequence: MHHESPIRRRKTRQIHVGKVAIGGDAPISVQSMTNTETRDIAATVAQIRRLEAVGADIVRISVPSMDAAEAFKTIRAQVETPLVADIHFDHRIALQVMEDGVDGLRINPGNIGSLDKTRLVVEMAKDKGIPIRIGVNAGSLEKDIQEKYGEPTPEALVESALRHVSILDELNFHDVKISVKASDIFLAVSAYRLLSEKVDYPLHLGITEAGGLRSGTVKSAIGLGLLLRDGIGDTIRVSLAADPVEEIRVGFDILKSLHLRQKGINLIACPSCSRQEFDVITTINALEARLEDILEPMDVSVIGCVVNGIGEAKEADIGLAGGDKRSILYYRGKQVDRVENNDIVDVLEKRIRAEIAERQATRHEG
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: ARCA_TOLAT
Sequence: MSEHTLGVHSETGILRQVIVCRPGLAHRRLTPSNCDALLFDDVFWVKQAQKDHDVFVSLMRARGVEVLDVNQLLAETLDIAEARSWILDHRISWNHIGVGMVSDLRAWMDELPGHVLAEFLIGGLQVNDLPFDPSGLFGNHLGPYGFILPPLPNFLFTRDNSSWIYGGVTLNPMYWAARKPETLLTAAIYQFHPKFSGKVEVLWGDPLKDHALATLEGGDIMPIGNRTVLVGMGERSSPQAIGQLANALFEHGTVDRVVACQIPKSRAAMHLDTVFTFCGGNVVTAFTEVADQMVCYDLRPGAGGKHLTFNQDPRPMFDVVAEALGYQSLTVIPTGGDTPAEREREQWNDGNNVLALSPGVVIGYDRNDDTNAALESAGIEVLKVPGAELGRGRGGGRCMSCPTIRDAI
What are the official names of this protein?
Arginine deiminase, ADI, Arginine dihydrolase, AD.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU5C_CYCTA
Sequence: MELIYKYVWIVPFLPLSASVPIGSGSLLFPRATRGLHHIWALISISLLGIAMLLSFNLFLQQITGGPVYQYLWSWTINKNFSPELGYLIDPLTSIMPISVTTVGIMVMIYSDNYMSHDQGYVRFFAYLSLFNASMLGLVISPNLVQIYIFWELVGMCSYLLIGSWFTRPSAANACQKAFITNRIGDFGLLLGILGFYQITGSFKFRYLLGRSNESIASNEVSSFFATLCAFLLFLGPVAKSAQFPLHVWLPDAMEGPTPISALIHAATMVAAGIFLVARLFPLFKALPFIMNLISWTGGITALLGATMALAQSDLKRGLAYSTMSQSGYMVLALGTGSYRAALFHPITHAYSKALLFLGSGSVIHSMESLVGYCPAESQNMALMGGLSKYMPITGTTFLLGTLSLCGIPPFACFWSKDEIISDSWLYSTILGGIARSAAGFTAFYMSRMYFLAFEGDLRVNLYNDPIPFYSISMWGEKESGTFTETEMGSMPQLPGNKNSSSSEGVFQFSGKMEQFDGKPMEYLVITHPLDKGDPPYPKESDNTMLLPSLVLGLFTLFVGSIGVSFVQGEISSDILSQRLTLSMNHFHENHPENWSEFFVDAIPSVGIAFSSTFVAFVLYGPINFNFSSPYLWYKRDSRLKGIPDRFINVIYNWSYYRGYIDIYYNKIFTMGIRRLAELTYLFDRWVIDGIIDRVGILGLFVGEGMKYLGGGRTSSYLFGFLFFAVIFLLTIFIFIWIR
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 5, chloroplastic, NAD(P)H dehydrogenase subunit 5, NADH-plastoquinone oxidoreductase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.