PharMolix/UniProtQA huggingface dataset:
Protein: ODO2_HAEIN
Sequence: MAIEILVPDLPESVADATVATWHKKLGDTVKRDEVIVEIETDKVVLEVPALSDGVLAEVVQAEGETVVSKQLLGKISTAQEGDVSSATLKATNEPTPSDRQNAAIENSHNHNADQSPVIRRLLAEHDLQADQIQGSGVGGRLTREDIEREIAKRQAQQVKQEAATEQNTISTVAYSARSEKRVPMTRLRKRIAERLLEAKNSTAMLTTFNEVDMQPIMTLRKTYGEKFEKQHSVRLGFMSFYIKAVVEALKRYPEVNASIDGDDVVYHNYFDISIAVSTPRGLVTPVLRDCDKLSMAEIEKQIKALAEKGRDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPPQSAILGMHAIKERPIALNGQVVIRPMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLEI
What is the function of this protein?
E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
What are the official names of this protein?
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, 2-oxoglutarate dehydrogenase complex component E2, OGDC-E2, Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoacid dehydrogenase family.
Protein: GYRB_BUCBP
Sequence: MKNTYTSSNIKILKGLDAVKKRPGMYIGNTDDGTGLHHMVFEVVDNSIDEALAGFCKNIIVTIHDDNSISIQDDGRGIPTDIHDEEGISAAEVIMTVLHAGGKFDNTSYKVSGGLHGVGVSVVNALSKKLELFIYRDKKIYYQIYKNGYPKNTLSIIGYTKITGTKIRFWPNLEIFTNVTQFNWEILSKRLRELSFLNSNVSIYLDDAKKHINENFYQQGGLKEFIIYLNKNKKPIHSKIFYFSSKKNNVEVEIAMQWNKGFQENIYCYTNNIPQQDGGTHLSGFRSALTRTMNNYLDKEGYIKKNKINIIGDDTREGLTAIISIKINDPKFSSQTKNKLVSSEVKSALESLVNEFLMEFLLENPQESKNIVTKIIESSRVRNAARRAREMTRKKGTLDLIGLPGKLSDCQERDPALSEIYLVEGDSAGGSAKQARNRKNQAILPLKGKILNVEKARYEKMLSSQEVTTLITALGCGIGKNEYNPEKLRYHRIIIMTDADVDGSHIRTLLLTFFYRYMPEIIQRGYLYIAQPPLYKVTKNNKTRYIKDKNTMENYKLSTALENTILESNTDKEIKIKCNYTLKKIISEYKIIQTIFFKIKDNFPLNILNEMLYHPKLNNLNDEVYVNNWINNFVIQLQKKSSSTRNYSAHITFNSKDKIFEPLIKIQKNAEVKEYKFDITFINSYEYQKIYSLGKKLQEMIQKNIHIKKNNKTYSIKNFQKNFELLIQNSFKNVLIQRYKGLGEMNPEQLWKTTMNPETRRMLKITLHNIDTTNKLFNTLMGDSVEPRKLFIELYALKASNIDI
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_STAAC
Sequence: MIEIEKPRIETIEISEDAKFGKFVVEPLERGYGTTLGNSLRRILLSSLPGAAVKYIEIEGVLHEFSAVDNVVEDVSTIIMNIKQLALKIYSEEDKTLEIDVRDEGEVTASDITHDSDVEILNPELKIATVSKGGHLKIRLVANKGRGYALAEQNNTSDLPIGVIPVDSLYSPVERVNYTVENTRVGQSSDFDKLTLDVWTNGSITPQESVSLAAKIMTEHLNIFVGLTDEAQNAEIMIEKEEDQKEKVLEMSIEELDLSVRSYNCLKRAGINSVQELADKSEADMMKVRNLGRKSLEEVKYKLEDLGLGLRKED
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: SODF_PSET1
Sequence: AFELPSLPYAIDALEPHISKETLEFHHGKHHNTYVVKLNGLIPGTKFENKSLEEIVCSSDGGVFNNAAQIWNHTFYWNSLSPNGGGAPTGAVADAINAKWGSFDAFKEALNDKAVNNFGSSWTWLVKLADGSLDIVNTSNAATPLTDDGVTPILTVDLWEHAYYIDYRNVRPDYLKGFWSLVNWEFANANFA
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Fe].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: LUTB_HALH5
Sequence: MGIKIGHASFDERVEKGIDNLFMRQAVSSAQERLKLAKAKAEEELGDWQEWRTLAEEIRSHTLDNLDYYLEQLSDNVSKNGGYVYFAQTAEEANVYIKEIAMKQQAKKIIKSKSMVTEEIGMNQALESIGCEVIESDLGEYILQIDDHDPPSHIVAPALHKNKEQIRETFKEKKGYSKSANPQELTLFAREQLRKEFLQADIGITGCNFAVAESGSITLVTNEGNARLATTIPKTQITVMGMERIVPTWEELDILVSMLCRSAVGQKLTSYVTGLTSTKEAGDVDGPEEFHLVIVDNGRSNILGTEFQAALHCIRCAACINVCPIYRHVGGHSYGSIYPGPIGAVLTPLLEGYDDHEELPYASSLCAACTDACPVKIPLHELLIKHRRVIAEQEKRTPLSESLAMKGFGLVASQPNLFKMGTKGAPYVLSPLTKDGSIKKGPGPLKGWTDIRDLPAAKKERFRDWFKTRGKGNIHHDSTTRDLSQ
What is the function of this protein?
Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source.  Has probably a role as an electron transporter during oxidation of L-lactate.
What are the official names of this protein?
Lactate utilization protein B.
What is the protein family that this protein belongs to?
Belongs to the LutB/YkgF family.
Protein: PHSC_STRVT
Sequence: MEDLQTRIAALSPKQRALFESRLRAAAAPGPDPAIPRRPDDDGPVPLSFAQHRLWFLDQLEPGRPVYNVSASLRIGRPVTTEAVRDALGALTRRHEVLRTVFPADGGEPRQHIADSLTPPLTETDLRALPDSARAAAALRLCAEDKQRPFDLSSGPLLRCLLLRLRDDDALLFLTFHHTVFDGWSIGLLRRDLTALLHAAETGTDAGLPPLPIQYADFADWQRRMLDEKRLGELLGYWRERIRGAPPVIDLPFDRPRPAVATTEGARRRFALPAELTTALRDLAARSGATPFMTMLTVFAALLHRWSGERDMVIGTPVANRARPELDDLIGFFANTLAMRVRIEPGMSFGDLLAQVRQTVVEALARQDLPFERLVDEARTERTLTHNPLFQVAFVMEDGRDASELDTLLPERARDTHTPDSAKFDLTLVLTDRESTYTGYFEYNTALFEPVTIDRLGERLALLARSVAADPGWELAALPVLTRDEIRHLKEVNAPVADDPRHHRTLHGVLEDSARRHPDHTAVEAPDRQLTYRELDEAANRLAHHLLALGVRPEQPVGVALDGTADAIVATFAVLKAGAVLLPLDPEYPAERLEHILRRSGATLLLTQRSLAGRFAGNDVTTVLLDDDATRAALADGPADRPGLPIAPDRLAYVIFTSGSTGVPKGVMVPHRGIGSLTRSAEQFAQTPDSRVLRFASPSFDVSLLELLMTFDAGATLVLEPRALLVPGEDLARLIRERRVSTVLLSPSALSTLTAGELPGLRTVVMAGEAATLELAQQWCDGRDVFNGYGPTEATVLATIARCAPDRVPPLGRPVAGYTVHVLDDTLRPVPFGRQGELFLGGVGLARGYLDQPDVTADRFLPDPSGTEPGARLYRTGDVVRWGADGELEFLGRTDHQVKLRGFRIELGEIETRLEDHPGVRTAVVLVRGEGSDRRLAGYAVRAPGEERPTAAGLRQWLRDRLPGYMVPELFLVLDALPTSPNGKLDREALPDPLAQSGDTAGNRPPLLDPVEERISGIWQEVLGIAPPGSADNFFEVGGNSLSATRIIARVNQAFGVRLPVRSLFVEPTLSGLARSVSAERAEELP
What is the function of this protein?
Involved in the biosynthesis of the antibiotic phosphinothricin tripeptide (PTT), which has bactericidal, fungicidal and herbicidal properties (PubMed:16251301).  Adenylates L-alanine and loads it onto a peptidyl carrier domain via a thioester linkage to the phosphopanthetheine moiety (PubMed:16251301).  Shows weaker activity with aminobutyric acid and L-serine (PubMed:16251301).
What are the official names of this protein?
Phosphinothricin tripeptide synthase PhsC, PTT synthase PhsC, L-alanine--[L-alanyl-carrier protein] ligase, Nonribosomal peptide synthase PhsC, Phosphinothricin tripeptide synthetase II, PTT synthetase II.
What is the protein family that this protein belongs to?
Belongs to the NRP synthetase family.
Protein: RL24_CHLCV
Sequence: MKRYSVCVGDTVYVLAGNDKGKQGKVLSCLREKNKVVVEGVNVRTKNIKRSQENPKGKRISIEAPIHVSNVRLSIDGAPAKLSVKVTENGRELWNKSPDGTSKLYRSVKERKG
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: ATPG_METC4
Sequence: MPSLKDLRNRITSVKATQKITKAMQMVAAAKLRRAQNAAENGRPYAERMAQVLGNLAGNLIGGVGAPRLLSGTGQDRVHLLVVCTGDRGLAGAFNSSIARLARDHANRLMADGKTVKIITIGKKGLDVLRRQFRDQIIASRDIRGNKPVDYPFAAEIADDILARFEAGEFDVATLFYSEFRSVISQIPTAQKLIPAELPTAEGASATGAGSDAAMEFEPNEETILETLLPKNLTVQIFRALLENAASEQGARMSAMDSATRNAGEMIKKQTLIYNRTRQAMITKELIEIISGAEAL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MURE_CHLTR
Sequence: MHLDQLLQNIPAKIYGKVESIPVRNLTRDSRCVGVGDIFIARQGQFCNGNDYSSQAVANGAIAVLSSLYNPFLSVVQIIAEDPIALEASLAARFYNNPSRHLDVIGITGTNGKTTVSCLVRELMERSGRRTGLIGTIEHILGENRIIDSFTTPDAILLQKYFAEMVKQNLSAAVMEVSSIGMALGRVRETEFLAGVLTNITSDHLDFHGSLEEYIAAKKQFFASLPEKGIAVVNLDCEYAPSFLNGSQARAVSYAIHQEADYRADRLKLYSSGSSYDIWYQGQVFPCETSLIGEHNVYNVLASLAVVHQFLGRDFADLVRDVRFLSAPKGRLDPILLGPFPVYIDYAHTPDALDNVCRILLQLLPKDGRLIIVFGCGGDRDRVKRPLMAKVSEHYGFSFVTSDNPRTEDPDQIIADICKGFSTDHYVVESDRKLAIEKAISMASDKDIVLVAGKGHEGYQIFKHQTIVFDDREVVCEALAALC
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPD_LACLM
Sequence: MTKVNSQKYSKALLEVAQEKGQLEAILTEVSEMIQLFKENNLGAFLANEVYSFSAKSELIDTLLQTSSEVMSNFLNTIRSNGRLADLGEILEETKNAADDMFKIADVEVVSSIALSEAQIEKFKAMAKSKFDLNEVTVINTVNEKILGGFIVNSRGKIIDASLKTQLAKIAAEIL
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: EX7S_PARUW
Sequence: MNNPSDQEPTASFETALCRLEEILEKMNSGTVSLDESLKLYEEADQLIIICNKRLNDAERKIEILVKNRSGELTLGNDDKPIIQDFKIASTS
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPASF_ARTSH
Sequence: MNRLLASALLVGSAVVAPVSAACIKNATVTEVDVAIIGGGASGVYAAARLIDNNKTVVVLERNADRIGGQTETYYDPTTGTPVNVGVKVFSNTTVTTDFLKRFDFPMGTLNVGQTLATGTQYVDFATGKLIPNFTAVVPAVQAAAMQRYAAELAKYPQIKFGYNLGPQVPEDLVLPFGKFMEKHNLTGMAQTMFEFNSGYTPLLEIPALYILKYLDTYELQSLQSGSFIVAANGDSATLYRNAAKFLGERVVYGVSGMHIQRSSAAGGRVTISVGNSTTGTHMIRAKKLIVAAPPTLDNLRSTGLDLDTTEAGLFGKLSAGVFYSLVVKDTGVAKANLRNRHPANPYGFPDQPFIYSVIPLPKTSGLAQVLLGSASPLTASQVEARVAADIGRLPASLRGNATSVPKVVTMAAHTWNVMAPVADIKAGFYDKLEGLQGLKDTWYIGAAWATQSSTTIWEGLEQEFLPKLLAAL
What is the function of this protein?
FAD-dependent oxidoreductase; part of the gene cluster that mediates the biosynthesis of the diterpenoid pyrones subglutinols A and B (PubMed:32286350).  The first step of the pathway is the synthesis of the alpha-pyrone moiety by the polyketide synthase dpasA via condensation of one acetyl-CoA starter unit with 3 malonyl-CoA units and 2 methylations (PubMed:32286350).  The alpha-pyrone is then combined with geranylgeranyl pyrophosphate (GGPP) formed by the GGPP synthase dpasD through the action of the prenyltransferase dpasC to yield a linear alpha-pyrone diterpenoid (PubMed:32286350).  Subsequent steps in the diterpenoid pyrone biosynthetic pathway involve the decalin core formation, which is initiated by the epoxidation of the C10-C11 olefin by the FAD-dependent oxidoreductase dpasE, and is followed by a cyclization cascade catalyzed by the terpene cyclase dpasB (PubMed:32286350).  The FAD-linked oxidoreductase dpasF is then involved in tetrahydrofuran (THF) ring formation at the C5 unit to complete the formation of subglutinols A and B (PubMed:32286350).  DpasF possesses also an additional catalytic ability of multi-step oxidations to generate a new DDP analog with an enone system at the C5 named FDDP A (PubMed:32286350).
What are the official names of this protein?
FAD-dependent oxidoreductase dpasF, Diterpenoid pyrone biosynthesis cluster protein E.
What is the protein family that this protein belongs to?
Belongs to the beta-cyclopiazonate dehydrogenase family.
Protein: MURD_BURP0
Sequence: MFGDRQRPMVLVLGLGESGLAIARWCARHGCRLRVADTRETPPNLAALTAAGVDFEFVGGAFSPALVDGGIELVALSPGLSPLAEDLAPLVAAARERGIPVWGELEFFAQALAALGANGYAPKVIAITGTNGKTTTTSLAGLLCERAGKKVAVAGNISPAMLDKLTEAIDAAALPDVWVLELSSFQLDTAHTFAPDAATILNITQDHLDWHGGFAAYAAAKGRVFGPRTVRVLNRDDAEVMRFAPPAAAADAPRAVTFGLNEPAADGDYGLLRENGIAWLVEAIDRDGADAPAAPSRRRKQEAANPPDIALKRLMPADALRIRGLHNAANALAAYALARAIGLPAAPLLHGLREYRGEPHRVEVIATLDGVDYVDDSKGTNVGATVAALDGLAQRAVLIAGGDGKGQDFEPLAAPVARWCRAVMLIGRDAPALREALADTGVPLADHATLEAAVRAASALAQPGDAVLLSPACASLDMFRNYAHRADVFRSAVEDIALEKGTTL
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_SHEAM
Sequence: MSRVAKAPVSIPAGVEVTLNGQEITVKGGKGTLTRVINSAVAVTVEDGAIKFAPVEGVVNAWAQAGTARALINNMVVGVSQGFEKKLQLVGVGYRAKVAGSDVDLSLGFSHPLVHKLPAGVTAECPSQTEIVLRSIDKELVGQVAAEIRGYRPPEPYKGKGVRYANEEVRRKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: YL288_MIMIV
Sequence: MSKTTFIIIAVIIILLLLALLGFLFYWRHRYRHTPTPPSSGPPVTPATPASITKAMQSGWGTIENQGNCLTATSNPGANTSIELQTCINPSSDNSSQQWKMTGNNSFISKLDPNGTYCLDVDGTASVGSSDQIHFWQCQQQDTTKMGWTPKITTNNPLNYQLVNNKTTSACLDASPGINKQPILQTCGANTTASQQWVFKPISS
What are the official names of this protein?
Putative B-type lectin protein L288.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: YABA_BACMK
Sequence: MEKKDIFASVSSMEEQIGHLYKQLGELKQHLAELLEENQHIKMENENLRHRFEEVQNKEKQKTQKRKEMKAKTDIGEGYDNLARLYQEGFHICNLHYGSVRKEGDCLFCLSFLNKK
What is the function of this protein?
Involved in initiation control of chromosome replication.
What are the official names of this protein?
Initiation-control protein YabA.
What is the protein family that this protein belongs to?
Belongs to the YabA family.
Protein: DNAJ_LACAC
Sequence: MAQEDYYKVLGVDRDASDQEISKAYRKLAKKYHPDLNHEPGAEEKYKQVNEAYEVLHDKQKRAQYDQFGSAGVNGQGGFGGAGQGFGGAGFDTSGFGDFGDIFGDIFGQGARQQRVDPTQPQRGQDLDYTLTIDFMDAINGKKTQVSYTRDETCETCGGNGCEKGTHPITCDKCHGTGVMTVTQQSMLGMIRRQTTCDKCNGRGVIIEHPCKTCGGKGTVERKNTIEVDIPAGIDNGQQLRYQGQGEAGRNGGPYGDLYISYRIKPSKDFERRGQNIYTEVPISFAQATLGDEITVKTVHGDAKLTIPAGTQPNKKFTLRGQGVPYLRGNGNGDQITTVNIVIPKHINDKQKEDLTNFVHDGGGNITPQEKGFFERLKDKLSGE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_METM6
Sequence: MSLMDPLANALNHVSNCESVGKNVAYLKPASKLIGRVLNVMQDQGYIGNFEYIEDGKAGVYKVDLIGQINKCGAVKPRFAVKNHDFEKFEKRYLPAKGFGLLIVSTPKGLMTHDEARSAGVGGRLISYIY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RISC_MOUSE
Sequence: MELSRRICLVRLWLLLLSFLLGFSAGSAIDWREPEGKEVWDYVTVRKDAHMFWWLYYATNPCKNFSELPLVMWLQGGPGGSSTGFGNFEEIGPLDTQLKPRNTTWLQWASLLFVDNPVGTGFSYVNTTDAYAKDLDTVASDMMVLLKSFFDCHKEFQTVPFYIFSESYGGKMAAGISVELYKAVQQGTIKCNFSGVALGDSWISPVDSVLSWGPYLYSMSLLDNQGLAEVSDIAEQVLDAVNKGFYKEATQLWGKAEMIIEKNTDGVNFYNILTKSSPEKAMESSLEFLRSPLVRLCQRHVRHLQGDALSQLMNGPIKKKLKIIPEDISWGAQASYVFLSMEGDFMKPAIDVVDKLLAAGVNVTVYNGQLDLIVDTIGQESWVQKLKWPQLSKFNQLKWKALYTDPKSSETAAFVKSYENLAFYWILKAGHMVPSDQGEMALKMMKLVTKQE
What is the function of this protein?
May be involved in vascular wall and kidney homeostasis.
What are the official names of this protein?
Retinoid-inducible serine carboxypeptidase, Serine carboxypeptidase 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS42_PHOLL
Sequence: MISKETFEIFPSVDIVDGIAMTSNSAIRLTRGESSTLRRPLGTPAEVALAWQNAGAKWIHVVDLDAASGRGSNSHLIADVLAAVDINVQVCGGIRDETILRKVLATGCQRVNLGTAALENPDWCAQAIAEYGDKIAIALDVKSTSEGYQLATHGWNVSKGNLWDLLERLDKQGCQRYVVTDVERGGMMSSPNFTLLQEVCAKTSSPVIAGGGVSSLDDLRALADLSTIGVEGAILGQALHIGKVPLEDALAATQSPRR
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 2, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase 2.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_LIMF3
Sequence: MAYDHKAIEKKWQRYWKQHKTFKATLDKDQKKYYALDMFPYPSGQGLHVGHPEGYTATDVMSRLKRMQGFNVLHPMGWDAFGLPAEQYALKTGHNPADFTNQNVDHFRDQIQSLGFSYDWDREVNTTDPNYYKWTQWIFEQLYKKGLAYEDEIMVNWAPDFMGGTVVANEEVVDGKTERGGYPVYRVPMRQWVLKITAYADRLIDDLDLVDWPESVKEMQRNWIGRSEGASVKFKVVGHDGVEIEVFTTRADTLFGASYVVLAPENELVDQLTTPEQKAAVDAYKEEVSRRSDLERTELSKEKTGVFTGAYVINPVNGEQLPIWTADYVLNSYGTGAVMAVPSGDQRDFEFATKFNLPITPVVEGFNGEEAYTEDGAHVNSGFLDGLNIKEAKAKMVEWLEEHDCGGKKVNYRLRDWIFSRQRYWGEPIPVIHWDDGTTSLVPEDELPLRLPETDNIEPSGTGESPLANIEDWVNVYDENGRHGKRETNTMPQWAGSSWYWLRYTDPTNDKEFASKEALDYWSPVDLYVGGAEHAVLHLLYARFWHKVLYDLGLVPTKEPFMKLVNQGMILGSNHEKMSKSKGNVVNPDDIVDQYGADTLRLYEMFMGPLEESVPWDEKGLHGSNKWVQRVWRLLMDDNNHLRDRVSTYNDGKLTKVYNQTVKKVTDDFERMHFNTAISQLMVFVNEAYKVDDLPLEYMKGFVKMIAPLMPHLAEELWSQFNESETITYQPWPTYDEKALVEDEVEMIVQVNGKVRAKIKMAKDADNKDVEDAALANEHVHSFVDGKDVKKVIVIPNRIVNIVVK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTFX_ECOL6
Sequence: MLTIQFLCPLPNGLHARPAWELKEQCSQWQSEITFINHRQNAKADAKSSLALIGTGTLFNDSCSLNISGSDEEQARRVLEEYIQVRFIDSDSVQPTLAELTAHPLPRSLSRLNPDLLYGNVLASGVGVGTLTLLQSDSLDSYRVIPASAQDSTLLEHSLATLAEQLNQQLRERDGESKTILSAHLSLIQDDEFAGNIRHLMAEQHQGLGAAIISNMEQICAKLSASASDYLRERVSDIRDISEQLLHITWPELKPRNNLVLEKPTILVAEDLTPSQFLSLDLKNLAGMILEKTGRTSHTLILARASAIPVLSGLPLDAIARYAGQPAVLDAQCGVLAINPNDAVSGYYQVAQTLADKRQKQQAQAAAQLAYSRDKKRIDIAANIGTALEAPGAFANGAEGVGLFRTEMLYMDRDSAPDEQEQFEAYQQVLLAAGDKPIIFRTMDIGGDKSIPYLNIPQEENPFLGYRAVRIYPEFAGLFRTQLRAILRAASFGNAQLMIPMVHSLDQILWVKGELQKAIVELKRDGLRHAETITLGIMVEVPSVCYIIDHFCDEVDFFSIGSNDMTQYLYAVDRNNPRVSPLYNPITPSFLRMLQQIVTAAHQRGKWVGICGELGGESRYLPLLLGLGLDELSMSSPRIPAVKSQLRQLDSEACRELARQACECRSAQEIEALLTAFTPEEDVRPLLALENIFVDQSFSNKEQAIQFLCGNLGVNGRTEHPFELEEDVWQREEIVTTGVGFGVAIPHTKSQWIRHSSISIARLVKPVDWQSEMGEVELVIMLTLGANEGMNHVKVFSQLARKLVNKNFRQSLFAAQDAQSILTLLETELTF
What is the function of this protein?
Multifunctional protein that includes general (non sugar-specific) and sugar-specific components of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS).  This major carbohydrate active transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II FryABC PTS system is involved in fructose transport.
What are the official names of this protein?
Multiphosphoryl transfer protein, MTP, Triphosphoryl transfer protein, TTP.
What is the protein family that this protein belongs to?
Belongs to the PEP-utilizing enzyme family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENOB_THUAL
Sequence: SITKIKAREILD
What is the function of this protein?
Glycolytic enzyme that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate.
What are the official names of this protein?
Beta-enolase, 2-phospho-D-glycerate hydro-lyase, Enolase 3, Muscle-specific enolase, MSE, Skeletal muscle enolase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_APUAP
Sequence: MAPNPRKSHPLLKMVNNSLIDLPTPPNISAWWNFGSLLGICLATQIITGLLLAMHYTADTTLAFSSVAHTCRNVQYGWLIRNLHANGASFFFICIYLHIGRGFYYGSYLYKETWNTGVILLLTLMATAFVGYVLPWGQMSFWGATVITNLFSAIPYIGQTLVEWAWGGFSVDNPTLTRFFALHFLLPFLIAGLTLIHLTFLHESGSNNPLGVVSNCDKIPFHPYFSTKDLLGFIIMLTPLLTLALFSPNLLGDPENFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASVLILFLCPFLHKSKQRTMTFRPLSQILFWVLVANLLILTWVGSQPVEHPFIIIGQLASLTYFTILLILFPLIGALENKMLNY
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.