PharMolix/UniProtQA huggingface dataset:
Protein: DXR_PHOV8
Sequence: MKKQIAILGSTGSIGTQALQVIEEHPDLYEVYALTANNRVDLLVEQARKFMPEAVVIANEEKYLQLKEALSDLPVKVYAGADALSQIVESQPIDIVLASMVGYAGLRPTINAIKAGKAIALANKETLVVAGELINALANQYHTPVLPVDSEHSAIFQCLEINNRLEKVILTASGGPFRTYTMEQLQTVTKAQALKHPNWEMGAKITIDSASMMNKGFEVIEAKWLFGMRPEQIEVVVHPQSVIHSMVQFEDGAVKAQLGMPDMRLPIQYAFSYPERVKSSFERLDFARITDLTFEQPDTKRFRNLALAYEALYRAGNMPCIVNAANEVVVDAFLKDKISFLGMSDVIEQTMGKVAYIKEPTYEDYVDTDAEARRVALSLLSS
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: Y8143_DICDI
Sequence: MKVSNLISTITIASALCLSLTNALVFSPCDKIQSLVKEYFDETIVDEMMCIAYNEAINPKSDSIGLWNLKKEHCNTVCKSICNSEIDLADIKLNTQCAEMVYLEFGFNGWDSYNNGLCKDSWGFCNTQNELRQHGSHSSTSRDSSSSSSRDSTGTGYSSSGSGTSGSGSNSGQTGHFIPGQSGHGLN
What are the official names of this protein?
Lysozyme C-like protein DDB_G0288143.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
Protein: DUR1_YEAST
Sequence: MTVSSDTTAEISLGWSIQDWIDFHKSSSSQASLRLLESLLDSQNVAPVDNAWISLISKENLLHQFQILKSRENKETLPLYGVPIAVKDNIDVRGLPTTAACPSFAYEPSKDSKVVELLRNAGAIIVGKTNLDQFATGLVGTRSPYGKTPCAFSKEHVSGGSSAGSASVVARGIVPIALGTDTAGSGRVPAALNNLIGLKPTKGVFSCQGVVPACKSLDCVSIFALNLSDAERCFRIMCQPDPDNDEYSRPYVSNPLKKFSSNVTIAIPKNIPWYGETKNPVLFSNAVENLSRTGANVIEIDFEPLLELARCLYEGTWVAERYQAIQSFLDSKPPKESLDPTVISIIEGAKKYSAVDCFSFEYKRQGILQKVRRLLESVDVLCVPTCPLNPTMQQVADEPVLVNSRQGTWTNFVNLADLAALAVPAGFRDDGLPNGITLIGKKFTDYALLELANRYFQNIFPNGSRTYGTFTSSSVKPANDQLVGPDYDPSTSIKLAVVGAHLKGLPLHWQLEKVNATYLCTTKTSKAYQLFALPKNGPVLKPGLRRVQDSNGSQIELEVYSVPKELFGAFISMVPEPLGIGSVELESGEWIKSFICEESGYKAKGTVDITKYGGFRAYFEMLKKKESQKKKLFDTVLIANRGEIAVRIIKTLKKLGIRSVAVYSDPDKYSQHVTDADVSVPLHGTTAAQTYLDMNKIIDAAKQTNAQAIIPGYGFLSENADFSDACTSAGITFVGPSGDIIRGLGLKHSARQIAQKAGVPLVPGSLLITSVEEAKKVAAELEYPVMVKSTAGGGGIGLQKVDSEEDIEHIFETVKHQGETFFGDAGVFLERFIENARHVEVQLMGDGFGKAIALGERDCSLQRRNQKVIEETPAPNLPEKTRLALRKAAESLGSLLNYKCAGTVEFIYDEKKDEFYFLEVNTRLQVEHPITEMVTGLDLVEWMIRIAANDAPDFDSTKVEVNGVSMEARLYAENPLKNFRPSPGLLVDVKFPDWARVDTWVKKGTNISPEYDPTLAKIIVHGKDRDDAISKLNQALEETKVYGCITNIDYLKSIITSDFFAKAKVSTNILNSYQYEPTAIEITLPGAHTSIQDYPGRVGYWRIGVPPSGPMDAYSFRLANRIVGNDYRTPAIEVTLTGPSIVFHCETVIAITGGTALCTLDGQEIPQHKPVEVKRGSTLSIGKLTSGCRAYLGIRGGIDVPKYLGSYSTFTLGNVGGYNGRVLKLGDVLFLPSNEENKSVECLPQNIPQSLIPQISETKEWRIGVTCGPHGSPDFFKPESIEEFFSEKWKVHYNSNRFGVRLIGPKPKWARSNGGEGGMHPSNTHDYVYSLGAINFTGDEPVIITCDGPSLGGFVCQAVVPEAELWKVGQVKPGDSIQFVPLSYESSRSLKESQDVAIKSLDGTKLRRLDSVSILPSFETPILAQMEKVNELSPKVVYRQAGDRYVLVEYGDNEMNFNISYRIECLISLVKKNKTIGIVEMSQGVRSVLIEFDGYKVTQKELLKVLVAYETEIQFDENWKITSNIIRLPMAFEDSKTLACVQRYQETIRSSAPWLPNNVDFIANVNGISRNEVYDMLYSARFMVLGLGDVFLGSPCAVPLDPRHRFLGSKYNPSRTYTERGAVGIGGMYMCIYAANSPGGYQLVGRTIPIWDKLCLAASSEVPWLMNPFDQVEFYPVSEEDLDKMTEDCDNGVYKVNIEKSVFDHQEYLRWINANKDSITAFQEGQLGERAEEFAKLIQNANSELKESVTVKPDEEEDFPEGAEIVYSEYSGRFWKSIASVGDVIEAGQGLLIIEAMKAEMIISAPKSGKIIKICHGNGDMVDSGDIVAVIETLA
What is the function of this protein?
Hydrolysis of urea to ammonia and CO(2).
What are the official names of this protein?
Urea amidolyase.
Protein: RECR_THET2
Sequence: MRYPESLLKLTRALSRLPGIGPKTAQRLALHLAFHKEEAEALAEALEGLKRVRACRECGNLAEGELCPICQDEDRDRSLLAVVESVADLYALERSGEFRGLYHVLGGALNPLEGIGPKELNLEGLFRRLEGVEEVVLATSMTVEGEATALYLAEELKKRGVRVTRPAYGLPVGGSLEYADEVTLGRALEGRRPV
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: BOWL_XENLA
Sequence: MDNINTTIDICGAASGLPSPGDSNSKRLRHRKYLPQRWKCEPRGPARTETQRPQTLFWRPWLLKSHKPKTQAHPYARGLRENPQEQKPVEYNHPVRLFWPKSKLLDNTYQEAADLLRNFPVQATISLYNDSESDTDNEEDSSEEEQDSGFESE
What is the function of this protein?
Required during somitogenesis for the formation of somite boundaries.  Represses the expression of genes involved in somite segmentation by acting with the corepressor tle4 to down-regulate the transcriptional activity of tbx6.  May act by regulating the activity of tle4.  Represses transcription of delta2, thy1 and ripply2. 2/bowline itself.
What are the official names of this protein?
Protein ripply2.2, Protein bowline.
What is the protein family that this protein belongs to?
Belongs to the ripply family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PARB_ECOLX
Sequence: MSKKNRPTIGRTLNPSILSGFDSSSASGDRVEQVFKLSTGRQATFIEEVIPPNQVESDTFVDQHNNGRDQASLTPKSLKSIRSTIKHQQFYPAIGVRRATGKIEILDGSRRRASAILENVGLRVLVTDQEISVQEAQNLAKDVQTALQHSIREIGLRLMRMKNDGMSQKDIAAKEGLSQAKVTRALQAASAPEELVALFPVQSELTFSDYKTLCAVGDEMGNKNLEFDQLIQNISPEINDILSIEEMAEDEVKNKILRLITKEASLLTDKGSKDKSVVTELWKFEDKDRFARKRVKGRAFSYEFNRLSKRVTGRTRQDDCGISLERASIKSRSLKLSPFKFHY
What is the function of this protein?
Control of plasmid partitioning; required to recognize the cis-acting partition sites.
What are the official names of this protein?
Plasmid Partition par B protein.
What is the protein family that this protein belongs to?
Belongs to the ParB family.
Protein: COXX_STAHJ
Sequence: MSKEQTLSQPSSRVSFKELQQIIKMGLVQGNLIPAFAGAWLAVVMSNHSFLSSIPQILLMLIGSTLIMGGACALNNYYDQDIDRIMPSKQNRPTVNDRISDKNLLILSFGMMLLGEACLFLLNVPSGVLGLIGIVGYVSYYSIWSKRHTTWNTVVGSFPGAVPPLIGWVAIDGNISLIAIALFLVVFCWQPIHFYALAIKRSDEYSLANIPMLPSVKGFKRTRISMFIWLVFLLPLPFLLSSLGTTFVVLATLLNLGWLYVGLTSFKKATDQTKWATKMFIYSLNYLVVFFVLVVVISLIKMI
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DCUP_NEIMF
Sequence: MTLLKNDTFLRALLKQPVEYTPIWMMRQAGRYLPEYKATRAKAGSFLDLCKNTELATEVTIQPLERFDLDAAILFSDILTVPDAMGLGLYFAEGEGPKFKRAMQHEADIAKLHVPDMEKLQYVFDAVTSIRKALDGRVPLIGFSGSPFTLACYMVEGGGSKEFRTIKTMMYSRPDLLHKILDTNAQAVTAYLNAQIDAGAQAVQIFDTWGGVLSDAAFKEFSLKYIRQIVAGLKRESEGRRVPVIVFAKGGGLWLESMAQIGADALGLDWTCNIGEARRRVGNQVALQGNFDPSALFGTPESIRAEVARILADYGHGSGHVFNLGHGINQHADPEHAKILVDTVHELSRQYHGG
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_HELP2
Sequence: MNAKALYKKKALRDRRKLRIKSKLLGDALRPRVSVFRSNRYFYAQAIDDVKQSTITHIDGRKMGFKNTQEDAKKLGALFAEELKKAGIERAVYDRNGYLYHGVVAAFAESLRENGIAL
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: IPO7_DICDI
Sequence: MDPIIQTIQLFQHTLHHDANVIKAAEAQLQQIKVTDGYSRILLKILASNEVDISIRQGVSIFLKNMIITKWRGAEDESPITQEDAEFIKENLIDLLVHSHHLVQNQIEAMIEIIANRDFPEKWTSLLPKSIQYINTQDVKLILAGLTSIQLGIKRFRYVTMGDKKKELLYTIVNEIFPLLLQILEFLSQHQTIESALMQKKVIKIFGYAIHFEIPDLLIQPEVFNKWLSQFVRIIQRPITPQENVKHADDCRKNQWWLLKRTTAKLLNLLFRKSATSVRSTDHSSVKALNKLFMPVYSVEVMKVFYEQLSTLEQLYKGVHYERYQQKLIEYFSFAIKYGVTYVAMKPWLSTLIQQVLFPIICFNDRDAELWECDPNEFLRSQFESSMTFATARIEVLNFIIDVVGKRGRANLDMIMGFCIQSLNKYNAATNASEKNPREKDGVLVIISVLSAYLKNISFYKSNLEQMLLLHVFPELSSPHGFLKARACSLFSEFYNIEFTDPVYFSNALKLILGLMSDNDLPVRVKAGTSICNLVRANQGVDELRPILPQLLDKIFSLLSEAESEDLVIAIESIIQRFKHEIAPYAVNLCKNLSEQFLRLLELEESDESGESGFASQECLGVYCTLLRALKDIPDVFNSLEQQIVPILQKLFTSDHMMYLDEALRILTFVTYYPKSISPLVWSLFPQIMNLFDECACDFASSYVNPLDNYISYGTEYFLSNQQYIEMVFNMYKKMVGDINQQPVDAGDCCKIMESLIQRAKGRIDYMIVPVLELACGRLLNTDKNNQKSKEFTVYLLEIIANCIYYNPLISTQYLESKNLVEPIFGLWFNRIKHFQRFYDKKISVLAFSSLLTLNPSPNFVKFGTSLILEKMLQFTKDMLSIEKELDKQEAEREQKIKDGTLKPEEEEFIDENDEEDYFDNHKFEFEFTEIPDNQDCQHDDEGEVFLDDIEKATEYFENGGDLGEDEGDNFDDQNDDDDQDSEEDLFEDEDTPDFETPIDEVDGFEFMINSIQNFFQINPTCIQQISEKQQEKIKKYVASAPARKEKLRLEKEKEEKLKQQQQKK
What is the function of this protein?
May function in nuclear protein import.
What are the official names of this protein?
Probable importin-7 homolog.
What is the protein family that this protein belongs to?
Belongs to the importin beta family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PDXB_ECOHS
Sequence: MKILVDENMPYARDLFSRLGEVTAVPGRPIPVAQLADADALMVRSVTKVNESLLAGKPIKFVGTATAGTDHVDEAWLKQAGIGFSAAPGCNAIAVVEYVFSSLLMLAERDGFSLHDRTVGIVGVGNVGRRLQARLEALGIKTLLCDPPRADRGDEGDFRSLDELVQHADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLTCLNEGQKLSVVLDVWEGEPELNVELLTKVDIGTPHIAGYTLEGKARGTTQVFEAYSKFIGHEQHVALDTLLPAPEFGRITLHGPLDQPTLKRLVHLVYDVRRDDAPLRKVAGIPGEFDKLRKNYLERREWSSLYVICDDASAASLLCKLGFNAVHHPAR
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPB10_ASFP4
Sequence: MLIPVVCFTCGFPIGTYAAIFDKARTEYIKTKMGGTLPQNIPLDASLQIELKDLITALGIPMRVCCRTHLITTLDYRKYY
What is the function of this protein?
Component of the DNA-directed RNA polymerase (RNAP) that catalyzes the transcription in the cytoplasm of viral DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase RPB10 homolog, RPB10 homolog.
What is the protein family that this protein belongs to?
Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: BIOB_STRA3
Sequence: MSFQTNYIHLADEILSGKTSISYEQALEILNSDENWWEIYAAALYLKNQVSRNNIRLNVLLSAKQGLCAENCGYCSQSKESTADIDKFGLLPQNVILKQAIVAHQNGASVFCIAMSGTKPSKREIEQLCQVIPEIKKSLPLEICLTAGFLDREQLHQLKQAGIDRINHNLNTPEENYPNIATTHSFKDRCDTLERIHNEDIDVCSGFICGMGESDEGLITLAFRLKELNPYSIPVNFLLAVEGTPLGKYNYLTPIKCLKIMAMLRFVFPFKELRLSAGREVHFENFESLVTLLVDSTFLGNYLTEGGRNQHTDIEFLEKLQLNHTKKELI
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: Y4806_VIBVY
Sequence: MFDDLPPLSHQEQQRAVEEIQKLMAEGMSTAQAIKIIAEKIRAEHKAQSAE
What are the official names of this protein?
UPF0181 protein VVA0806.
What is the protein family that this protein belongs to?
Belongs to the UPF0181 family.
Protein: RL33_ECOLU
Sequence: MAKGIREKIKLVSSAGTGHFYTTTKNKRTKPEKLELKKFDPVVRQHVIYKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RRP36_AJECN
Sequence: MPISSKLNQRVRARLREEDFEHFSDESVSNESLDERESNEDTEQDNRDQRETDDDDTEDDGHTEISDINPSLNTISFGALAKAQAALGKRKRRTTSTTDITPKRTKVLSRQSPTPSTSSNKEHDQGQGLSEFQKHLASNAKKPPQKLTHRTSKHAPTIQSSRHAVSRKRTIIEPLAAPKPRDPRFDSVVLSHSTNGNPSTAANADIHARNNYAFLNHYRTDEIAELRKQVSALQTKKKKTERDDHEIVRLKREITSMSDRQRAFERKEMEREVLVQHRRREKELIREGKKSQPYFLKKGEVKKEVIAKRFTEMSGKEKQRALERRRKKVVGKERKEMPWGRRGVE
What is the function of this protein?
Component of the 90S pre-ribosome involved in the maturation of rRNAs.  Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity).
What are the official names of this protein?
rRNA biogenesis protein RRP36, Ribosomal RNA-processing protein 36.
What is the protein family that this protein belongs to?
Belongs to the RRP36 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PYRH_XANC5
Sequence: MSELSYRRILLKLSGEALMGDGDYGIDPKVINRLAHEVIEAQQAGAQVALVIGGGNIFRGAGLAASGMDRVTGDHMGMLATVINALAMQDALEKLGAKVRVMSAIKINDVCEDFIRRRAIRHLEKGRIAIFAAGTGNPFFTTDSGAALRAIEIGADLLLKATKVDGVYDKDPKKHTDAVRYDSLTYDQVILQGLEVMDTAAFALARDSDLPLRIFGMSEPGVLLRILHGEQIGTLVQGRS
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX1_SYNY3
Sequence: MTIAAENLTANHPRRKWTDYFTFCVDHKVIGIQYLVTSFLFFFIGGSFAEAMRTELATPSPDFVQPEMYNQLMTLHGTIMIFLWIVPAGAAFANYLIPLMVGTEDMAFPRLNAVAFWLTPPGGILLISSFFVGAPQAGWTSYPPLSLLSGKWGEELWILSLLLVGTSSILGAINFVTTILKMRIKDMDLHSMPLFCWAMLATSSLILLSTPVLASALILLSFDLIAGTSFFNPVGGGDPVVYQHLFWFYSHPAVYIMILPFFGVISEVIPVHARKPIFGYRAIAYSSLAISFLGLIVWAHHMFTSGTPGWLRMFFMATTMLIAVPTGIKIFSWCGTLWGGKIQLNSAMLFAFGFLSSFMIGGLTGVMVASVPFDIHVHDTYFVVGHFHYVLFGGSAFALFSGVYHWFPKMTGRMVNEPLGRLHFILTFIGMNLTFMPMHELGLMGMNRRIALYDVEFQPLNVLSTIGAYVLAASTIPFVINVFWSLFKGEKAARNPWRALTLEWQTASPPIIENFEEEPVLWCGPYDFGIDTELMDDEETVQTLIADAAGS
What is the function of this protein?
Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Subunits 1-3 form the functional core of the enzyme complex.  CO I is the catalytic subunit of the enzyme.  Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome aa3 subunit 1, Cytochrome c oxidase polypeptide I, Oxidase aa(3) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL11_ARTS2
Sequence: MAPKKKVTGLIKLQIQAGAANPAPPIGPALGQHGVNIMEFCKAYNAATEAQRGNVIPVEITVYEDRSFTFITKTPPAAELIKKAAGVAKGSATPHTVKVAKLTQAQVNEIASTKMEDLNATSLEGAAKIIAGTARSMGITVEG
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: FMT_STRGG
Sequence: MKLVFAGTPEVAVPALDALIASDRHEVAAVVTRPDAPAGRGRRLVASPVAERAQEAGIEVLKPAKPRDEEFLARLREIAPDCCPVVAYGALLPKVALDVPARGWVNLHFSLLPAWRGAAPVQHAVMAGDEVTGASTFLIEEGLDSGPVYGVLTEEVRPTDTSGDLLTRLAFAGAGLLAATMDGIEDGTLHAVPQPHEGVTLAPKITVEDAQVQWSAPALRVDRVVRGCTPAPGAWTVFRGERLKLIQATPVLDRTDLAPGELSAAKNNVYVGTGSHAVELLWVQPQGKKPMRGADWARGVRIAHGELLGP
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: DEF_SALAR
Sequence: MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEGIGLAATQVDIHQRIIVIDVSENRNERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGNPFELEADGLLAICIQHEMDHLVGKLFIDYLSPLKQQRIRQKVEKLDRLNARA
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: SMY2B_DANRE
Sequence: MMKAEGIPGIEQFASPGKGRGLRVSRAYGVGELLFSCPAYSYVLSVGERGLICEQCFTRKKGLAKCGKCKKAFYCNANCQKKNWPMHKLECQAMCAFGENWRPSETVRLVARIIARLKAQKERSPSEILLLLGEMEAHLEDMDNEKREMTEAHIAGLHQFYSKHLDFPDHQALLTLFSQVHCNGFTVEDEELSNLGLAIFPDIALLNHSCSPNVIVTYRGINAEVRAVKDISPGQEIYTSYIDLLYPTADRLERLRDMYYFSCDCKECTTKSMDVVKMSVRKRSDEIGEKEIKDMVRYARNSMENFRRAKQDKSPTELLEMCELSIDKMSTVFDDSNVYILHMMYQAMGICLFTEDYEGAVRYGEKVIKPFTVLYPAYSMNVASMFLKLGRLYIALDRKLAGIDAFQKALTIMEVVHGKDHTYVTELKQEMRDF
What is the function of this protein?
Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1.  Specifically trimethylates histone H3 'Lys-4' (H3K4me3) in vivo.  The activity requires interaction with HSP90alpha.  Shows even higher methyltransferase activity on p53/TP53.  Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53.  Monomethylates RB1 at 'Lys-860'.
What are the official names of this protein?
N-lysine methyltransferase SMYD2-B, Histone methyltransferase SMYD2-B, SET and MYND domain-containing protein 2B.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus.
Protein: XERC_SYNAS
Sequence: MDELIKEFDRYMDLERNLSTHTRKNYLSDLNQFKIYLEENHRVPTELKTEAWQNVDYMMVRAFLGALYRRRVKKVTIARKLASLRAFFKYLHQKRKIQCNPLEAVSTPRTEKYIPAVLSVDEIFVLLNLPFPEDVFGLRDRAILELFYSSGIRVSELTGINEEDMDFSQGLIRIRGKGKKERIVPIGQPASEAVQRYMMKKPGSETSGKAVATCPVPLFVNRRQGRLSARSVARILSKYVSMSGLQKQISPHTLRHSFATHLMDAGADLRSIQELLGHESLSTTQKYTAVSVNRLMAVYDRAHPKARGGH
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PONL1_MOUSE
Sequence: MRPQELLLLLLMLKWSLAHTEDPAFPHLGDSSQPLPRPCPWRCSCPRDDTVDCAGLDLRIFPDNITRAARHLSLQNNQLRELPYNELSRLSGLRTLDLHSNLITSEGLPDEAFESLNQLENFYVAHNKLSVAPQFLPRSLRVADLAANEVVEIFPLTFGEKPALRSVYLHNNRLRNTGLPPNTFHGSEVITTLSLSSNQLSYLPPSLPASLERLHLQNNLISKVPRGALSLQTHLRELYLQHNQLTDSGLDATTFSKLSSLEYLDLSHNQLATVPEGLPGTLTILHLGRNCIRHVEAVRLHKARGLRYLLLQHNKLGASALPKGTLRPLRALHTLHLYGNKLERVPPALPRHLQALVMPHNHVAALGARDLVSARALAELNLAYNSLASAHVHPSAFRRLRALRSLDLAGNQLTRLPEGLPASLRSLRLQRNQLRTLEPEQLAGLNKLRELNLAHNRLRVGDIGPGTWHELQALKVLDLSHNELSFVPPDLPEALEELYLQANRISHVGPEAFLSTPHLRALFLRANRLHMTSIRAEALQGLTHLRVVDTAENPEQVLV
What are the official names of this protein?
Podocan-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class V subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: THIC_PSYA2
Sequence: MTISDIGSQASTTTSSKATAKADALKTPAHRSETDARFEEDARDLHRILPASRKVYIEGSRPDIQVPMREITLDPTPIQGVPESEWEQNPPFYVYDTSGVYTDPNTTIDLTKGLPKLREEWIKERGDTEQLSGLSSDYGQARARDISTANLRFAHIDKPRRAKAVDGKVGNVTQMHYARRGIITPEMEYIAIRETQKQHELTDMRQHEGETFGAHTPAIITPEFVRSEVAAGRAIIPNNINHPESEPMIIGRNFLVKINANIGNSALGSSIDEEVSKMTWATRWGADNIMDLSTGNHIHETREWLIRNSPVPIGTVPIYQALEKVDGVAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTANRLTGIVSRGGSIMAQWCLAHHKESFLYTHFEDICEIMKQYDVAFSLGDGLRPGCLQDANDEAQFGELRTLGELTQVAWKHDVQVMIEGPGHVAMNRIKENMDLQLETCADAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPNKKDVKDGIITYKIAAHAADLAKGHPGAQARDNALSKARFEFRWDDQFNLALDPDTAREFHDETLPKDAHKSAHFCSMCGPKFCSMKITQNVRDYAAGLKTLADTKNSVSPQSGALNDAEHLIKKVDTQLVEQVGSASAEEIHQGMAEMTEKYHKEGRQLYKEV
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: ATG15_VANPO
Sequence: MISNDYTKFSSKRRSLRYSNRILLLMGTILLIVVYFYSDILVDKSIIMFRNENKGQMLSGSFTLRHIYRHGVDKGHRTQEVLDITKQNEDAFGRYFKRELDEFNANAVGLNTDDPLRELWTSDKQFITDNPFNFKFGLKGNKQILHRMVDRDPSFIEPYLDFARESPDMAAKVTIDWVEGGEVVVVPDITDKNTVVSLALMSSNAYVRLPYTDDWRNVSLPWDSNDTPGYGWESNGIRGHVFVNDLENIVVISIKGTSAQGLPGSGEDETTGNDKLNDNLLFSCCCARVSYLWTTVCDCYLKSYTCDETCLEQAIKEKDHYYQAAMDIYKDTLRQYPHATIWLTGHSLGGALASLVGRTYGLPTVAFESPGELLAAKRLHLPFPPGLPSYDEGIWHIGHTADPIYMGTCNGASSTCSIAGYAMETGCHSGKQCVYDVVRDKGWHVNMLNHRIHTVIDGILTKYDKVATCHEPDPCVDCYNWNFMPHGKKPKKQTTSSSSEKVDTSTTKSIDRTTITTRTNEKKWHPNPKDPSTTTTDDKTLMSSCLHRNWVGICTEYTTFTKRLI
What is the function of this protein?
Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies.  Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles.  The intravacuolar membrane disintegration by ATG15 is critical to life span extension (By similarity).
What are the official names of this protein?
Putative lipase ATG15, Autophagy-related protein 15.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Endosome, multivesicular body membrane; Single-pass type II membrane protein. Prevacuolar compartment membrane; Single-pass type II membrane protein. Note=From ER, targeted to vacuolar lumen at the MVB vesicles via the Golgi and the prevacuolar compartment (PVC).
Protein: ESPG1_MYCS2
Sequence: MTAPFTAETGDAHIDDVVGVEVTIDGMLVIADKLGLTDFPPSMGIRLNIPQPDLRKVVWEQVERDLSAQGVLDVYGNPHPEVAAMVDTLARADRTLECRWWRRDAGGKMIRFVVCRKGGRHVVAARDNDLLVLQRVAPQIGLAGMVMTVLGEGSPANVEPLTGVADRLAQCRTAEELTGYGIPPTSARAYASIISEPDGWVEIVANERHPGGTTSQVDVAAGVLDAKQGRIVSIPRRVNGELYGSFLSGTKDNLERALEGLVEFLPSKTWFDKTDADNAYQH
What is the function of this protein?
Part of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB (PubMed:15687187).  Specific chaperone for cognate PE/PPE proteins, plays an important role in preventing aggregation of PE/PPE dimers (By similarity).  Also plays a role in DNA conjugation, in at least recipient strain (By similarity).
What are the official names of this protein?
ESX-1 secretion-associated protein EspG1.
What is the protein family that this protein belongs to?
Belongs to the EspG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRNHD_ARATH
Sequence: MAKRGESLRDKPKWSLEGMTALVTGGSKGLGKAVVEELAMLGARVHTCARDETQLQESLREWQAKGLQVTTSVCDVSSRDQREKLMETVSSLFQGKLSILVPNVGIGVLKPTTECTAEEFSFIIATNLESTFHFSQLAHPLLKASGSGNIVLMSSVAGVVNLGNTSIYGATKGAMNQLARNLACEWASDNIRANSVCPWFITTPSTKDFLGDKDVKEKVESVTPLRRVGEANEVSSLVAFLCLPAASYITGQTICVDGGFTINGFSLP
What are the official names of this protein?
Tropinone reductase homolog At2g29370.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. SDR65C subfamily.