PharMolix/UniProtQA huggingface dataset:
Protein: PDK4_HUMAN
Sequence: MKAARFVLRSAGSLNGAGLVPREVEHFSRYSPSPLSMKQLLDFGSENACERTSFAFLRQELPVRLANILKEIDILPTQLVNTSSVQLVKSWYIQSLMDLVEFHEKSPDDQKALSDFVDTLIKVRNRHHNVVPTMAQGIIEYKDACTVDPVTNQNLQYFLDRFYMNRISTRMLMNQHILIFSDSQTGNPSHIGSIDPNCDVVAVVQDAFECSRMLCDQYYLSSPELKLTQVNGKFPDQPIHIVYVPSHLHHMLFELFKNAMRATVEHQENQPSLTPIEVIVVLGKEDLTIKISDRGGGVPLRIIDRLFSYTYSTAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSGYGTDAIIYLKALSSESIEKLPVFNKSAFKHYQMSSEADDWCIPSREPKNLAKEVAM
What is the function of this protein?
Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2.  This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate.  Inhibition of pyruvate dehydrogenase decreases glucose utilization and increases fat metabolism in response to prolonged fasting and starvation.  Plays an important role in maintaining normal blood glucose levels under starvation, and is involved in the insulin signaling cascade.  Via its regulation of pyruvate dehydrogenase activity, plays an important role in maintaining normal blood pH and in preventing the accumulation of ketone bodies under starvation.  In the fed state, mediates cellular responses to glucose levels and to a high-fat diet.  Regulates both fatty acid oxidation and de novo fatty acid biosynthesis.  Plays a role in the generation of reactive oxygen species.  Protects detached epithelial cells against anoikis.  Plays a role in cell proliferation via its role in regulating carbohydrate and fatty acid metabolism.
What are the official names of this protein?
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial, Pyruvate dehydrogenase kinase isoform 4.
What is the protein family that this protein belongs to?
Belongs to the PDK/BCKDK protein kinase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: Y824_CLONN
Sequence: MARGGFPGMGGGMNINNLMKQAQKMQQQMQKVQGELEEKEFVASAGGGAVTVKANGKKEILSINIEPDVVDPDDVEMLQDLILAACNQALKTADEETANEMKKLTGGLNMPGMF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein NT01CX_0824.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: ACCA_CHLTA
Sequence: MELLPHEKQVVEYEKTIAEFKEKNKENSLLSSSEIQKLDKRLDRLKEKIYSDLTPWERVQICRHPSRPRTVNYIEGMCEEFVELCGDRTFRDDPAVVGGFAKIQGQRFMLIGQEKGCDTKSRMHRNFGMLCPEGFRKALRLAKMAEKFGLPIIFLVDTPGAFPGLTAEERGQGWAIATNLFELARLATPIIVIVIGEGCSGGALGMAIGDVVAMLEHSYYSVISPEGCASILWKDPKKNSDAAAMLKMHGEDLKGFAIVDAVIKEPIGGAHHNPAATYRSVQEYVLQEWLKLKDLPVEELLEKRYQKFRTIGLYETSSESDSEA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_HELMI
Sequence: MRIMGLDVGDKTIGVAVSDLMGWTAQGVATIRRSRLAADLEHLRELVKTYEVERIVCGLPRNMNGTYGPRAEGIRKFGSLVEKKLNIPVDYWDERLTTVAAQKTLIAGDLSRAKRKQVVDKLAAVLILQNYMDAKAHLAAKEQSKETSE
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_WIGBR
Sequence: MQNRKKILTTCAFPYANGSLHIGHILEHIQADIWVRFNRMIGNEIYFICADDSHGTPIMIKAKKNKISPEKMVFLFYKEHKNDLSKFNISYDNYYLTHSKENYRFCKLIYKLLKRKKLIFSKYISQFYDCKINMFLSDRLIQGKCPECNSEKQYSDNCNICGANYCSTDVINPISILSKSVPIIKKSKHLFFDLPKFEKFLKKWIHSGVLKKENLRKVSEWFKNGLKPWDISRDAPYFGFKIPNEKEKYFYVWLDAPIGYLSTFKNLCDKKEKIFFSEFWDVNSKSEIYQFIGKDVIYFHSLFWPAILHGINLKKPTKLFVHGHVTLNGEKMSKSNGFVIKAKTYLKYCDSDFLRYYFSMKISSCAKDIDFSLSDFMNKVNSNIINKIVNLASRSSSFIDKYFEGYLSYKIENYELYCKFTSLKEKINKYFQSNNISFIIYEIIKLAELANQYFNKKSPWKLTEESKDKRNKLHEISSMGINMFYIIMIYLKPILPNLSKKTEDFLNISLKWENINKPLLYPHLINKFKPLCNRITKSQINYIKRESTIK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CNTO_PSEAE
Sequence: MRVSVSLVLGVGLGCSSPALWAETESPAELEVLTVTAEAERAEGPVQGYRANRTASATRTDTRIEDIPQAISVVPRQVLDDLDSARIERALDFAGGVSRQNNFGGLTMFEYNVRGFTTSEFYRDGFSANRGYMNAPDSATIERVEILKGPASSLYGRGDPGGTVNLVTKKPQAERFARLHASAGSWDRYRSTLDLNTPLDEEGDLLYRMNLAVEDSKGFRDYADGQRLLVAPSISWQLDPDTSLLVEAEVVRNRQVFDRGTVAPHNHLGSLPRSRFFGEPDDGKIDNNNETLQATLRHHFNEQWSLRLASHYKHGHLDGYASENSSLAADGYSLRREYRYRDFEWHDSITQLDLLGDLHTGSIRHQLLMGLEYERYHNDELILRSIPSRNPYAIDIRRPVYGQPKPPFGRDDRNHEEVDAMALNLQDQIEFSEKWRGLLGVRFDRYRQDMNATRLNNGRFRETSSQQTQRAATPRIGVLYQATPEVGLFANASKSFKPNGGTDMAGKAFDPEEGRGYEAGVKLDLLDGRLGMTLAAFHLKKKNVLTADPSNPGYQQTAGEARSQGFDLQFSGQLTEQLRLIGAYAYIDAEVTKDENIARGSRLLNVPKHSGSLMGVYEFREGWLHGADAGAAVNYVGERAGDSSDSGFELPAYTTVDLLARYPLASNATLGVNVNNLFDRRYYERSYNNVWVAPGEPRNLTMSLTLNY
What is the function of this protein?
Transports the metallophore pseudopaline, which is involved in the acquisition of nickel and zinc, and thus enables bacterial growth inside the host, where metal access is limited.  Is probably involved in the import of pseudopaline-metal complexes.
What are the official names of this protein?
Metal-pseudopaline receptor CntO.
What is the protein family that this protein belongs to?
Belongs to the TonB-dependent receptor family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: HBB1_SAAHA
Sequence: VHWTAEEKALINAYWGKVDVGSVGGETLANLLVVYPWTQRFFEDFGNLSTPSAILNNPKXXXXXXXVITSFGDALKNLDNVXXXXXKLSEYHCNKLHVDPVNFRLLGDVLITLSAANFGKXXXXXXXXXXXXLVGVVAHALARRYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta-1, Beta-1-globin, Hemoglobin beta-1 chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RS9_CORGL
Sequence: MSEPIQNENVESNVADAADIAAATAATEEFTNTIGDAIATASEEETIEAAPVVLDGPIQTVGRRKRAIVRVRLVAGSGEFKCNGRTLEEYFPNKLHQQLIKAPLVLLDRENQFDIVATLKGGGPTGQAGAFRLAIARALNAYNPAERGELKKAGFLTRDARAVERKKAGLHKARRAPQYSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: H2B01_CYRHA
Sequence: MKVTLIAILTCAAVLVLHTTAAEELEESQLMEVGMPDTELAAVDEERLFECSVSCEIEKEGNKDCKKKKRKGGWKCKFNMCVKV
What is the function of this protein?
Postsynaptic neurotoxin.
What are the official names of this protein?
U4-theraphotoxin-Hhn1aa, U4-TRTX-Hhn1aa, Hainantoxin-II-2, HNTX-II-2.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 12 (Hwtx-2) family. 02 (Hwtx-2) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS19_ECO57
Sequence: MPRSLKKGPFIDLHLLKKVEKAVESGDKKPLRTWSRRSTIFPNMIGLTIAVHNGRQHVPVFVTDEMVGHKLGEFAPTRTYRGHAADKKAKKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: GWT1_KLULA
Sequence: MDASGVIDELKHRKEAFVTGHSGSSIADLRDVTLAGIFSNAAWIYVVSNNPSYRDSFWLDFLLNWMGLLCSVTVFGENPFLTGILGLSAVLLFGCISKGSKRETIKETVMDNGNQSATLTVYRSTMLILTSIAILAVDFPIFPRKYAKVETWGISLMDLGVGSFVFSNGIISYKRLKSGTELSKWAKIKQSLRSTVVLVVLGFIRLFSVKAVNYQEHATEYGIHWNFFFTLSLLPLAMIIFDFYNMRLRFVIGLIAAIIYELCLIYHPTFLDYLLNAERIDFISANREGIFSFVGYCIIYLAGQQVGSMFFPISRNPMQLLWKLVALSIFSSAISYVLLHYHPLQVSRRFASIGYSSMVISFNLLILTFDQLIVECLTSKPRVPKTYRAVNGNGMLVFLISNVTTGMVNFTFNTLDSPPYKAMAILTVYALFLAVFALKVPFKLKF
What is the function of this protein?
Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.
What are the official names of this protein?
GPI-anchored wall transfer protein 1.
What is the protein family that this protein belongs to?
Belongs to the PIGW family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: CB068_BOVIN
Sequence: MEAAPSPGSGLCCKPGGRLDMSHGFVHHIRRNQLARDDYDKKVKQAAKEKARRRHTPAPTRPRKPDLQVYLPRHRDGSTHPSNPDCEESGESSSSGSSEPEPPGHQLFCLEYEADSGDITSVIVYQDDDPGRVSEEVSAHTPLEPLMREALKLRIQEEIAKRQSRH
What are the official names of this protein?
UPF0561 protein C2orf68 homolog.
What is the protein family that this protein belongs to?
Belongs to the UPF0561 family.
Protein: AMPP3_METRA
Sequence: MAVEDFEAVLKAKYPGKAHAKRVVDLIRKTKPDANGVIYLEGRMTKLLEDNDSPEHFRQRRYFYYLTGCNLADCSFAYDIQSSKSILFIPPIDPDDVIWSGLPLSIDEALSRYDVDEVKFTTEVNSTLAHLAKQSPNSTVFAIANQVSDSVTFLEFGSKDFETVKKAIEVSRVVKDEFEVAMIRKANHISSLAHKAVIERSKAAATEQELYATFLERCVSHAAPEMAYHPILAAGKAAATLHYVDNNAPLKGKQNLLIDAGCEWNNYASDITRTFPLTGTFTKESRDIYDIVLRMQKECTELIKGGMLWDDLHLHAHKVAIDGLLALGILKGDAKEILNARTSAAFFPHGLGHHLGMDTHDTGGNPNPNDPDKLFRYLRLRGHVPAGAVVTVEPGIYFCDFIIKPYLDDHVHSKYIDAAVLNKYWDVGGVRIEDNIHVTENGYVNLTTAIKEVSDVEAVSAK
What is the function of this protein?
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.
What are the official names of this protein?
Probable Xaa-Pro aminopeptidase pepP, Aminoacylproline aminopeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: MVP_LMVE
Sequence: MATLDNCTQVHHMFAYNREHGTNYTRNHFRRYLAAQRIGFYYDWDDDVYECPTCEAIYHSLDEIKNWHECDPPAFDLNDFITDARLKSAPVPDLGPVIVETPKVEEKQELNFFAATPAPEVLQWKCRGLQFGSFTELETSEPVVSAPKPNCEEPARTIAKPEEPVEQETCGDGKRLLQAQMEVDKAEQDLAFAYLSASLKPRLEGRTTATIARRRDGCLVYKTKPSWSQRKGTKKILKVDTLACKNPYIPAVVDKISIAGGSSASVMHEQQKPKILHTTPSRKVATHYKRTVMNQQTLTALINQVGTIILNAEKEFEVVGCRKQKVTGKGTRHNGVRLVKLKTAHEEGHRRKVDIRIPNGLRSIVTRISARGGWHKTWTDSELSPGSSGYVLNSSKIIGEFGLRRHSIFVVRGRVYGKIIDSQSKVTHTLTHRMVQYSDVARNFWNGYSTCFMHNTPKDILHTCTSDFDVKDCGTVAALLTQTLFQFGKITCGKCAIEYKNLTRDELATRVNKEIDGTIISIQTQHPRFVHVLNFLRLIKQVLNAKNGNFGAFQETERIIGDRMDAPFSHVNKLNAIVIKGNQATSDEMAQASNHVLEIARYFKNRTENIQKGSLKSFRNKISGKAHLNPSLMCDNQLDKNGGFEWGQRSYHAKRFFDGYFETIDPSDGYSKYTIRRNPNGHRKLAIGNLIVSTNFESHRRSMVGEPIEDPGLTNQCVSKEGGAFIYPCCCVTDEYGKPTLSEIKMPTKHHLVLGNAGDPKYVDLPKEAEGKMFVAKDGYCYINIFLAMLVDVPEDQAKDFTKMAREIAVKQLGEWPSMMDVATACNILATFHPDTRRSELPRILVDHATKTFHVIDSYGSITTGYHILKANTVTQLVKFAHESLESEMQHYRVGGEPDKAPRKPAGNVPTLGISDLKNLGVESENEEHSIRPNLQRLIKAIYRPRMMRSLLTEEPYLLILSIVSPGVLMALYNSGSLERTMHEFLQTDQRLSATAQILKHLAKKVSLAKTLTIQNAILEGGAGSLNEILDAPAGRSLSYRLAKQTVEVMMARSDMDKELVDVGFSVLRDQKNELIEKKLSHGFGGLVARIAIVWKIISNASLAAMAGHLYSRSNPNRCRRFERQIQYLGWVCFQKRDLAPKGNLLRRSKES
What is the function of this protein?
Allows efficient cell to cell propagation, by bypassing the host cell wall barrier.  Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding (By similarity).
What are the official names of this protein?
P3N-PIPO polyprotein.
What is the protein family that this protein belongs to?
Belongs to the potyviridae P3N-PIPO polyprotein family.
What are the subcellular locations of this protein?
Host cell junction, host plasmodesma.
Protein: Y462_NEIMF
Sequence: MTFLQRLQGLADNKICAFAWFVVRRFDEERVPQAAASMTFTTLLALVPVLTVMVAVASIFPVFDRWSDSFVSFVNQTIVPQGADMVFDYINAFREQANRLTAIGSVMLVVTSLMLIRTIDNTFNRIWRVNSQRPWMMQFLVYWALLTFGPLSLGVGISFMVGSVQDAALASGAPQWSGALRTAATLTFMTLLLWGLYRFVPNRFVPARQAFVGALATAFCLETARSLFTWYMGNFDGYRSIYGAFAAVPFFLLWLNLLWTLVLGGAVLTSSLSYWRGEAFRRGFDSRGRFDDVLKILLLLDAAQKEGKALPVQEFRRHINMGYDELGELLEKLARHGYIYSGRQGWVLKTGADSIELNELFKLFVYRPLPVERDHVNQAVDAVMTPCLQTLNMTLAEFDAQAKKQQQS
What are the official names of this protein?
UPF0761 membrane protein NMC0462.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SSAJ_SALTY
Sequence: MKVHRIVFLTVLTFFLTACDVDLYRSLPEDEANQMLALLMQHHIDAEKKQEEDGVTLRVEQSQFINAVELLRLNGYPHRQFTTADKMFPANQLVVSPQEEQQKINFLKEQRIEGMLSQMEGVINAKVTIALPTYDEGSNASPSSVAVFIKYSPQVNMEAFRVKIKDLIEMSIPGLQYSKISILMQPAEFRMVADVPARQTFWIMDVINANKGKVVKWLMKYPYPLMLSLTGLLLGVGILIGYFCLRRRF
What is the function of this protein?
Component of Salmonella pathogenicity island 2 (SPI-2) type III secretion system, required for secretion of some type III-secreted effectors including the SpvB toxin.
What are the official names of this protein?
Secretion system apparatus lipoprotein SsaJ.
What is the protein family that this protein belongs to?
Belongs to the YscJ lipoprotein family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: CINA_GEOSW
Sequence: MNAEIIAVGSELLLGQIANTNAQFLSEKLAELGINVYFHTVVGDNAGRLEQAVRVAQARAELIIFTGGLGPTKDDLTKETIARLLGRELVIDEEALRSIEAYFARTNRTMTENNKKQALVLQGSTILKNEHGMAPGMAITLNSITYMLLPGPPKEMQPMFLKYGRPFLMEQLGRHERIESRVLRFFGIGESQLETDIEDLIDQQSNPTIAPLAGDGEVALRLTAKHHSEIEAKKLLDKAEQAILERVGRYFYGYNDETLFKKTVKMLKEKKKTIAAAESLTGGLFLTELTAIPGASQVVRGGVVCYANEVKEKVLHVPASVLTTDGAVSERCAQLLAENVRTLCHADIGISFTGVAGPDPLEGKPVGTVYIGISTPENETEVYALALPGQRDAIRIRTAKYGCSIILKKLAAAYEG
What are the official names of this protein?
Putative competence-damage inducible protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: MIAB_CAMC1
Sequence: MSKKLFIQTLGCAMNVRDSEHIIAELSQKEDYSLTQNIEEADLILINTCSVREKPVHKLFSEVGAFEKAKKRGAKIGVCGCTASHLGSEIFKRAPYVDFVLGARNVSKITKAVNTPKFISTDINHDESEYAFGEFRGSPYKSHINISIGCDKKCTYCIVPHTRGDEISIPSSLILKEVEKAAKSGAKEIFLLGQNVNNYGKRFSGVQENIDFSDLLVKISEIEGVERIRFTSPHPLHMDDKFLEIFTNNPKICKSMHMPLQSGNTKVLREMKRGYTKEWFLDRALRLRKMCPDVSISTDIIVAFPGESDNEFEDTMDVLEQVRFEQIFSFKYSPRPLTKAATFINQIDDKTASERLTRLQNRHSEILDEIVAAQKDKIFDVYFEELRANGGVAGRSFNNFLVQVDGSEELLGTTQKAKITNPKRMVLYGELQI
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS25_LEIIN
Sequence: MPPKAGQTKKAKMEAANKGAKKTTKKWSKGQSREALQNAVMFDKETYDKLRSEVPKYKLITPSIISDRLKIAVSIAAAGLKQLCREKLIRLVSCSSKTRVYTRIVQAAPAEAAAAAPAAE
What are the official names of this protein?
40S ribosomal protein S25.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS25 family.
Protein: PYRC_SALSV
Sequence: MTAPSQVLKIRRPDDWHVHLRDGDMLKTVVPYTSEIYGRAIVMPNLASPITTVDAAIAYRQRILDAVPAGHDFTPLMTCYLTDSLDADELERGFHEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKLGMPLLVHGEVTHADVDIFDREARFIDTVMEPLRQRLTALKVVFEHITTKDAAQYVRDGNDYLAATITPQHLMFNRNDMLVGGIRPHLYCLPILKRNIHQQALRELVASGFTRAFLGTDSAPHSRHRKETSCGCAGCFNAPSALGSYAAVFEEMNALAHFEAFCSLNGPQFYGLPVNTGWVELVRDEQQIPENIALADDSLVPFLAGETVRWSVKK
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: QUEE_DESVH
Sequence: MTYRVKEIFHTLQGEGMRAGRAAVFCRFSGCNLWTGWAQDRPAAVCPFCDTDFVGTDGPGGGVFEDAATLAAAILAAFPYKTGEGYRPYVVFTGGEPALQLDRPLIDILHAHGCEVAIETNGTVRLPEGIDWVTVSPKAGTRLAVTSGDELKLVWPQQGICPESYESLAFTYLLMQPRDGLGDAGRGDAESEAVRWCLAHPRWRLCLQTHKYLGIP
What is the function of this protein?
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
What are the official names of this protein?
7-carboxy-7-deazaguanine synthase, CDG synthase, Queuosine biosynthesis protein QueE.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Protein: RS10_BIFA0
Sequence: MAGQKIRIRLKSYDHEVIDQSAKKIVETVTNAGATVVGPVPLPTEKNVYCVIRSPHKYKDSREHFEMRTHKRLIDIVDPTPKAVDSLMHIDLPADVNIEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: PSD_HELP2
Sequence: MVALSNALSRVFGSVAGYKFPSFIQKGINALYAKIFKVDLSEFEPLENYKSLNALFTRSLKKERPFDKAPNICIAPCDALITECAFLDNDSALQIKGMPYKAHELVGEINPLSPSFFYVNFYLSPKDYHHYHAPCDLEILETRYFAGKLLPVNKPSLHKNKNLFVGNERVALVTKDIQGNRLYFVAVGALNVGKMRFNFDKNIQTNAKARFTQTYSYNPPIKVKKGDNLGNFEMGSTIVLFVQNTAFKDLKEKSVKFGESIGEFHAN
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: DSBB_ALIF1
Sequence: MQALNHFSRIRLSWFLLLLCIIFFEASALTFQHIMKLPPCVMCIYERVAMMGIGGAAIIGLLNPNNLIIRWCGFIAWGISAGWGLKLALEHVDFQLNPSPFSTCDLFVTFPSWAPLNKWAPWMFEAYGDCSKIVWQFLTLTMPQWLVIIFAGNLIALAIFVIAQFFNKK
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by oxidizing the DsbA protein.
What are the official names of this protein?
Disulfide bond formation protein B, Disulfide oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the DsbB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HFLC_ECOLI
Sequence: MRKSVIAIIIIVLVVLYMSVFVVKEGERGITLRFGKVLRDDDNKPLVYEPGLHFKIPFIETVKMLDARIQTMDNQADRFVTKEKKDLIVDSYIKWRISDFSRYYLATGGGDISQAEVLLKRKFSDRLRSEIGRLDVKDIVTDSRGRLTLEVRDALNSGSAGTEDEVTTPAADNAIAEAAERVTAETKGKVPVINPNSMAALGIEVVDVRIKQINLPTEVSEAIYNRMRAEREAVARRHRSQGQEEAEKLRATADYEVTRTLAEAERQGRIMRGEGDAEAAKLFADAFSKDPDFYAFIRSLRAYENSFSGNQDVMVMSPDSDFFRYMKTPTSATR
What is the function of this protein?
HflC and HflK help govern the stability of phage lambda cII protein, and thereby control the lysogenization frequency of phage lambda.  HflKC inhibits the SecY-degrading activity of FtsH, possibly helping quality control of integral membrane proteins.
What are the official names of this protein?
Modulator of FtsH protease HflC.
What is the protein family that this protein belongs to?
Belongs to the band 7/mec-2 family. HflC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: GLRB_MOUSE
Sequence: MKFSLAISFFILMSLLFEDACAKEKSSKKGKGKKKQYLCPSQQSPEDLARVPPNSTSNILNRLLVSYDPRIRPNFKGIPVDVVVNIFINSFGSIQETTMDYRVNIFLRQKWNDPRLKLPSDFRGSDALTVDPTMYKCLWKPDLFFANEKSANFHDVTQENILLFIFRDGDVLVSMRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGDPVQLEKIALPQFDIKKEDIEYGNCTKYYKGTGYYTCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSLASECTTLAAELPKVSYVKALDVWLIACLLFGFASLVEYAVVQVMLNNPKRVEAEKARIAKAEQADGKGGNAAKKNTVNGTGTPVHISTLQVGETRCKKVCTSKSDLRSNDFSIVGSLPRDFELSNYDCYGKPIEVNNGLGKPQAKNKKPPPAKPVIPTAAKRIDLYARALFPFCFLFFNVIYWSIYL
What is the function of this protein?
Glycine receptors are ligand-gated chloride channels.  GLRB does not form ligand-gated ion channels by itself, but is part of heteromeric ligand-gated chloride channels.  Channel opening is triggered by extracellular glycine (PubMed:12809985).  Heteropentameric channels composed of GLRB and GLRA1 are activated by lower glycine levels than homopentameric GLRA1.  Plays an important role in the down-regulation of neuronal excitability.  Contributes to the generation of inhibitory postsynaptic currents (PubMed:12809985, PubMed:16672662).
What are the official names of this protein?
Glycine receptor subunit beta, Glycine receptor 58 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRB sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Synapse. Cell projection, dendrite. Cell membrane; Multi-pass membrane protein. Cytoplasm. Note=Retained in the cytoplasm upon heterologous expression by itself. Coexpression with GPHN promotes expression at the cell membrane. Coexpression with GLRA1, GLRA2 or GLRA3 promotes expression at the cell membrane.
Protein: LAC2_TRAVI
Sequence: MGLQRFSFFVTLALVARSLAAIGPVASLVVANAPVSPDGFLRDAIVVNGVVPSPLITGKKGDRFQLNVVDTLTNHSMLKSTSIHWHGFFQAGTNWAEGPAFVNQCPIASGHSFLYDFHVPDQAGTFWYHSHLSTQYCDGLRGPFVVYDPKDPHASRYDVDNESTVITLTDWYHTAARLGPKFPLGADATLINGLGRSASTPTAALAVINVQHGKRYRFRLVSISCDPNYTFSIDGHNLTVIEVDGINSQPLLVDSIQIFAAQRYSFVLNANQTVGNYWVRANPNFGTVGFAGGINSAILRYQGAPVAEPTTTQTPSVIPLIETNLHPLARMPVPGSPTPGGVDKALNLAFNFNGTNFFINNATFTPPTVPVLLQILSGAQTAQDLLPAGSVYPLPAHSTIEITLPATALAPGAPHPFHLHGHAFAVVRSAGSTTYNYNDPIFRDVVSTGTPAAGDNVTIRFQTDNPGPWFLHCHIDFHLDAGFAIVFAEDVADVKAANPVPKAWSDLCPIYDGLSEANQ
What is the function of this protein?
Lignin degradation and detoxification of lignin-derived products.
What are the official names of this protein?
Laccase-2, Benzenediol:oxygen oxidoreductase 2, Diphenol oxidase 2, Urishiol oxidase 2.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS10_TREDE
Sequence: MTKEKIRVKLRGFDVELVDQSSKAIVQAVQKAGAKVCGPIPLPTRINKFTVLRSPHVNKKSREQFEMRTHKRLIDIIEPSAEVMNALLALELSAGVDVEIKQ
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.