PharMolix/UniProtQA huggingface dataset:
Protein: GH_MEHV1
Sequence: MKFYCLIRFMIIANLYSSYQISLPGTYPSQILLDMKNSPLVRFNISTRDYKDETLWIRKNSTFVYIDTAVTTANVIFYLPIGQVRQMVFFKRPISRLLTSNNLVKFINTGSYANHTFKTELSPYLSKTNTPLKKYEIVVDQPTGENPPAGFGSLKPADFLNPGYKFVLTSELVGAYTKRSCFVDPMDSLVPIDYDHVRTIIFGSAGMEILMKMGITLASMTISTKYNPPIELIISAKYRNLSLLWPPRQQYEPVNKGTGRPHWIYLLGVYRNVSDSERDSYMNMIKSLGDSMDYHFLISRAHAQMLILAAEDRLVDEMHSFRNVIARLFVSLFAFIRNAFQSGYTSLNDIIEIEADLRLIVEGISSAAFRKDASTHFLISGTPIKDSKADLIKSLLSKVIRPISGHTRPLSAIQHLFLLRSAYALDIPRQNGSLSEQVSTVALSFIENIHSEAMRDILSWNTTTKHALYYAFASILQRPLTEWGASRNARRAILLASSMCTEEHVIATELAIQELYVKIRSNADPIHLLDVYTPCLSSLRLDLSEHHRIYAMADVVFYPDIQQYLKKKSHEGNMKEDDLETKAEYILTKLRSPLIRTLSAYASEVLSCSDQDLLEINAILILPVSGIGSYVVSRRAGMQGIVYTVDGVDVNNQLFITYTRMPCTTTIGNIVPTVLSRPSGKTCPYCGCVLLRYSADGNIRYSIYISSPKLQSELIAFGNSSIRRFNPTTAQIYGNSLLLYPNGTIVRILAFESERVTIISATYIATAVAGSIIALTVIVITVRMIIINMRYNYQGYNKVIDVDDDIRN
What is the function of this protein?
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell.  Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL.  May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis.
What are the official names of this protein?
Envelope glycoprotein H, gH.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein H family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN).
Protein: Y6576_BACAN
Sequence: MLNKCFIKNYNYNIQLVRYIESKHSNTFQIIKDYMDTLVYSVKSKFDDYDIALLTMLFETKRMSQNTKVKRVYLYNSYSFIHQNYITALLKEAFKGVIEIVEKDTLNLTYEGLQKKNVDIIISNVKLEIKDIPVVQISDMPTDKELSKIKKLL
What are the official names of this protein?
Putative trans-acting regulator pXO2-62/BXB0076/GBAA_pXO2_0076.
What is the protein family that this protein belongs to?
Belongs to the AtxA/AcpA family.
Protein: Y1374_THEAB
Sequence: MKKLKSFGGKNLSGKSMNQLQKLQEEMQKKLQEVEEGFSNVEVEVSVGGGAIKILATADRKVKDIEIDEDLLSDGETLKDLLTAGINELMEKIEKIREEEMAKVTQNLLPFGF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein THA_1374.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: CYB6_PEA
Sequence: MSKVYDWFEERLEIQAIADDITSKYVPPHVNIFYCLGGITLTCFLVQVATGFAMTFYYRPTVTEAFASVQYIMTEANFGWLIRSVHRWSASMMVLMMILHVFRVYLTGGFKKPRELTWVTGVVLGVLTATFGVTGYSLPWDQIGYWAVKFVTGVPDAIPVIGSSXVELLPASASVGQSTLTRFYSLHTFVLPLLTAVFMLMHFLMIRKQGIFGPL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: COX2_KAZEX
Sequence: MLNLFQIMNMINNDVPTPYGFYFQDSATPNQEGILELHDNIMFYLVVILGLVSWMLFTIVRTYSRNPMAYKYIKHGQTIEIIWKIFPAVILLTIAFPSFILLYLCDEVISPAMTIKAIGYQWYWKYEYFDFINDNGETIEFESYVIPDSLLEEGQLRLLDTDTSIVVPVDTHIRFIVTAADVIHDFAIPSLGIKVDGTPGRLNQVSTLIQREGVFYGMCSELCGIGHAQMPIKVEAVSLPKFLEWLNEQ
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
Protein: S35B1_BOVIN
Sequence: MAASSSLVPDRLRLPLCFLGVFVCYFYYGILQEKITRGKYGEGAKQETFTFALTLVFIQCVVNAVFAKILIQFFDTARVDRTRSWLYAACSVSYLGAMVSSNSALQFVNYPTQVLGKSCKPIPVMLLGVTLLKKKYPMAKYLCVLLIVAGVALFMYKPKKVVGIEEHTIGYGELLLLLSLTLDGLTGVSQDHMRAHYQTGSNHMMLNINLWSTLLLGAGILFTGELWEFLSFAERYPTIVYNILLFGLTSALGQSFIFMTVVYFGPLTCSIITTTRKFFTILASVILFANPISPMQWVGTVLVFLGLGLDAKFGKGAKKTSH
What is the function of this protein?
ATP:ADP antiporter that catalyzes the exchange of ATP and ADP across the endoplasmic reticulum (ER) membrane.  Imports ATP from the cytosol to the ER lumen and exports ADP in the opposite direction.  Regulates ER energy metabolism and protein biogenesis.  Appears to be part of a calcium-dependent ER to cytosol low energy response axis, where calcium efflux from ER to the cytosol triggers ATP import into the ER lumen to maintain sufficient ATP supply.  Provides ATP to ER chaperone HSPA5 that drives protein folding and trafficking in the ER.  Can transport dATP, UTP or UDP in exchange for ATP, but the physiological relevance of this process remains to be established.
What are the official names of this protein?
Solute carrier family 35 member B1, ATP/ADP exchanger ER, AXER, Endoplasmic reticulum ATP/ADP translocase, UDP-galactose transporter-related protein 1, UGTrel1.
What is the protein family that this protein belongs to?
Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: C71B4_ARATH
Sequence: MVSLLSFFLLLLVPIFFLLIFTKKIKESKQNLPPGPAKLPIIGNLHQLQGLLHKCLHDLSKKHGPVMHLRLGFAPMVVISSSEAAEEALKTHDLECCSRPITMASRVFSRNGKDIGFGVYGDEWRELRKLSVREFFSVKKVQSFKYIREEENDLMIKKLKELASKQSPVDLSKILFGLTASIIFRTAFGQSFFDNKHVDQESIKELMFESLSNMTFRFSDFFPTAGLKWFIGFVSGQHKRLYNVFNRVDTFFNHIVDDHHSKKATQDRPDMVDAILDMIDNEQQYASFKLTVDHLKGVLSNIYHAGIDTSAITLIWAMAELVRNPRVMKKAQDEIRTCIGIKQEGRIMEEDLDKLQYLKLVVKETLRLHPAAPLLLPRETMADIKIQGYDIPQKRALLVNAWSIGRDPESWKNPEEFNPERFIDCPVDYKGHSFELLPFGSGRRICPGIAMAIATIELGLLNLLYFFDWNMPEKKKDMDMEEAGDLTVDKKVPLELLPVIRISL
What are the official names of this protein?
Cytochrome P450 71B4.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MINC_PHOLL
Sequence: MSQSPIELKGSNFTLSVVHLHNDQPEIILQALQEKVEQAPDFLKNAPVVINISALPADADLKALHHAIDSAGFRIVGMSGCRDEQQRRAVIKASLPLLSEGKKQKTSAKEDKPAEPAIKKTRVINLPVRSGQRIYAQGSDLIVTSNVSAGAELIADGNIHIYGMMRGRALAGASGDQECLVFCTHLNAELISIAGQYWLGDKIPTELAGKAAKLSLVNNELTIEPLI
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: SPDS1_DATST
Sequence: MEEANNKESPYISSILPGWFSEISPLWPGEAHSLKVEKILFQGKSDYQNVMVFQSSTYGKVLILDGVIQLTERDECAYQEMITHLPLCSIPNPKKVLVIGGGDGGVLREVSRHSSVEQIDICEIDKMVIDVSKQFFPNVAIGYEDPRVKLHVGDGVAFLKFVAEGTYDAVIVDSSDPIGPAQELFEKPFFESVARALRPGGVVCTQAESIWLHMHIIEDIVANCRQIFKGSVNYAWTTVPTYPSGVIGFMLCSTEGPAVDFKNPINPVDADDSHTKTRGPLKFYNSEIHSASFCLPSFAKRVIESKGK
What are the official names of this protein?
Spermidine synthase 1, SPDSY 1, Putrescine aminopropyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
Protein: RL16_THEP1
Sequence: MLMPRRVKYRKQQRGRMKGKAKGGTFVQFGEWGLKALEPAWITAQQIEACRIAMLRAMKRSGKIWIRIFPDKPYTKKPPESRMGKGKGNVEGWVAVVKPGKILFEVAGVDEETAHEALRYAASKLPIATKVVPRHHIGGEAV
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: SEC4_CANAX
Sequence: MSGKGTSSRAYDMIMKLLLVGDSGVGKSCLLLRFVEDKFNPSFITTIGIDFKIRTIESKGKRIKLQVWDTAGQERFRTITTAYYRGAMGIVLIYDVTDSRSFENVENWFQTVTQHANEDAQIFLVGNKCDDEVNRQVSKEQGQELAAKLNVPFLEASAKSNENVDSIFYELASIIQEKHVEENIGGVGGASGAGGIDVSQNNSGAKNNCC
What is the function of this protein?
Involved in exocytosis.  Maybe by regulating the binding and fusion of secretory vesicles with the cell surface.  The GTP-bound form of SEC4 may interact with an effector, thereby stimulating its activity and leading to exocytotic fusion.  SEC4 may be an upstream activator of the 19. 5S SEC8/SEC15 particle.  SEC4 probably interacts directly with SEC8; it could serve as the attachment site for the SEC8/SEC15 particle (By similarity).
What are the official names of this protein?
Ras-related protein SEC4.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle membrane; Lipid-anchor; Cytoplasmic side. Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: DBHB_ECOLI
Sequence: MNKSQLIDKIAAGADISKAAAGRALDAIIASVTESLKEGDDVALVGFGTFAVKERAARTGRNPQTGKEITIAAAKVPSFRAGKALKDAVN
What is the function of this protein?
Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
What are the official names of this protein?
DNA-binding protein HU-beta, HU-1, NS1.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: KIF11_HUMAN
Sequence: MASQPNSSAKKKEEKGKNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPLAGIIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITALVERTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPEVNQKLTKKALIKEYTEEIERLKRDLAAAREKNGVYISEENFRVMSGKLTVQEEQIVELIEKIGAVEEELNRVTELFMDNKNELDQCKSDLQNKTQELETTQKHLQETKLQLVKEEYITSALESTEEKLHDAASKLLNTVEETTKDVSGLHSKLDRKKAVDQHNAEAQDIFGKNLNSLFNNMEELIKDGSSKQKAMLEVHKTLFGNLLSSSVSALDTITTVALGSLTSIPENVSTHVSQIFNMILKEQSLAAESKTVLQELINVLKTDLLSSLEMILSPTVVSILKINSQLKHIFKTSLTVADKIEDQKKELDGFLSILCNNLHELQENTICSLVESQKQCGNLTEDLKTIKQTHSQELCKLMNLWTERFCALEEKCENIQKPLSSVQENIQQKSKDIVNKMTFHSQKFCADSDGFSQELRNFNQEGTKLVEESVKHSDKLNGNLEKISQETEQRCESLNTRTVYFSEQWVSSLNEREQELHNLLEVVSQCCEASSSDITEKSDGRKAAHEKQHNIFLDQMTIDEDKLIAQNLELNETIKIGLTKLNCFLEQDLKLDIPTGTTPQRKSYLYPSTLVRTEPREHLLDQLKRKQPELLMMLNCSENNKEETIPDVDVEEAVLGQYTEEPLSQEPSVDAGVDCSSIGGVPFFQHKKSHGKDKENRGINTLERSKVEETTEHLVTKSRLPLRAQINL
What is the function of this protein?
Motor protein required for establishing a bipolar spindle during mitosis (PubMed:19001501).  Required in non-mitotic cells for transport of secretory proteins from the Golgi complex to the cell surface (PubMed:23857769).
What are the official names of this protein?
Kinesin-like protein KIF11, Kinesin-like protein 1, Kinesin-like spindle protein HKSP, Kinesin-related motor protein Eg5, Thyroid receptor-interacting protein 5, TR-interacting protein 5, TRIP-5.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. BimC subfamily.
Protein: GPR3_MOUSE
Sequence: MMWGAGSSMAWFSAGSGSVNVSSVDPVEEPTGPATLLPSPRAWDVVLCISGTLVSCENALVVAIIVGTPAFRAPMFLLVGSLAVADLLAGLGLVLHFAADFCIGSPEMSLMLVGVLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTRTYVMLALVWVGALGLGLVPVLAWNCRDGLTTCGVVYPLSKNHLVVLAIAFFMVFGIMLQLYAQICRIVCRHAQQIALQRHLLPASHYVATRKGIATLAVVLGAFAACWLPFTVYCLLGDADSPRLYTYLTLLPATYNSMINPVIYAFRNQDVQKVLWAICCCCSTSKIPFRSRSPSDV
What is the function of this protein?
Orphan receptor with constitutive G(s) signaling activity that activate cyclic AMP.  Has a potential role in modulating a number of brain functions, including behavioral responses to stress, amyloid-beta peptide generation in neurons (By similarity) and neurite outgrowth (By similarity).  Maintains also meiotic arrest in oocytes.
What are the official names of this protein?
G-protein coupled receptor 3, GPCR21.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GRCA_SALNS
Sequence: MITGIQITKAANDDLLNSFWLLDSEKGEARCIVAKSGFAEDEVVAVSKLGEIEYREIPMEVKPEVRVEGGQHLNVNVLRRETLEDAVKHPEKYPQLTIRVSGYAVRFNSLTPEQQRDVIARTFTESL
What is the function of this protein?
Acts as a radical domain for damaged PFL and possibly other radical proteins.
What are the official names of this protein?
Autonomous glycyl radical cofactor.
Protein: PSD_DECAR
Sequence: MSDRLAVLPQYLIPKQALTVLAGKLASAKAGGLTTSVIRWFVRRYNVNMTEAANPDIASYKSFNEFFTRPLKDGARPAADADFLCPVDGAISQYGTIDRDQIFQAKGHSYSTTALVGGDRKLAEQFENGSFATLYLSPRDYHRIHMPCDGKLTRMIYVPGALFSVNPTTARGVPGLFARNERVICVFESEFGSFVLTLVGATIVGSMATVWHGTINPPRPGVIREWRYDEQNIRLKKGQEMGRFLLGSTVVMLFPKNTLAFNPDWSPSRAIRMGEQMGSNAN
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: UPPP_STRPI
Sequence: MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNEAFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGVFKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYIGLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKAGELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSFVRLFV
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YDIR_BACSU
Sequence: MTFIKRLEDAYETLLGNYPAGVSSTSTSKYNEIRKIVSEAFLIGENEVYVTGTSRRISNLDTRFAQGNQRNKHTRMAVAFISIPSVDDSELDELIIRTRNSAITTSSKFCNGEERGTIFDGILLFLVFEGETKVYPLAFLVFENDFELKEKAEELIPGIELKEYPRANQSPAQENNKSAKNEDEESAKSYVVFLDIEEDGSIVEFVEDKDKTYRIGDMIWTASHTNGSSAITRRLEVIEVVENLVVCKIKHKYNEPVDKNSLLKFVNIEQDLISFLDLHPNVQNGSEGFVSGDIVDENATTSSDDLPEDFENN
What is the function of this protein?
A P subtype restriction enzyme that recognizes the double-stranded sequence 5'-CTCGAG-3'; the cleavage site is unknown.
What are the official names of this protein?
Type II restriction enzyme BsuMI component YdiR, R.BsuM, R.BsuMI, Endonuclease BsuMI component YdiR, Type-2 restriction enzyme BsuMI component YdiR.
Protein: ISPDF_HELP2
Sequence: MSLIRVNGEAFKLSLESLEEDPFETKETLETLVKQTSVVLLAAGESRRFSQIIKKQWLRSNHTPLWLSVYESFKEALDFKEILLIVSELDYIYIQRHYPEIKLVKGGASRQESVRNALKIIDSTYTLTSDVARGLANMEALKSLFLTLQQTSHYCIAPYLPCYDTAIYYNEALDREAIKLIQTPQLSHTKALQSALNQGDFKDESSAILQAFPNRVSYIEGSKNLHKLTTSGDLKHFALFFNPAKDTFIGMGFDTHAFIKDKPMVLGGVVLDCEFGLKAHSDGDALLHAVIDAILGAIKGGDIGEWFPDNDPKYKNASSKELLKIVLDFSQSIGFELFEMGATIFSEIPKITPYKPAILENLSQLLGLEKSQISLKATTMEKMGFIGKQEGLLVQAHVSMRYKQKL
What is the function of this protein?
Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
What are the official names of this protein?
Bifunctional enzyme IspD/IspF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the IspF family.
Protein: TRMA_PSEAB
Sequence: MSRPQFDPSAYAAQLEDKKSRLAGLLAPFAAPAPEIFESPREHYRLRAEFRLWRETGNEKRHYAMFEQGDKHTPILIEDFPIASRRINELMPRLKAAWADPALGFKLFQVEFLTTLAGDALITLCYHRPIDDAWRQAAEKLAAELGVNLVGRSRGKRIVVGRDYVEEELSVAGRRFRYRQPEGAFTQPNGEVNQKMLGWAYEALGQRDDDLLELYCGNGNFTLPLATRVRKVLATEISKSSVNAALANLADNAVDNVSLVRLSAEELTQALNEVRPFRRLADIDLKSYAFGNVFVDPPRAGMDPDTCELTRRFERILYISCNPETLAQNIAQLHDTHRISRCALFDQFPYTHHMESGVLLERR
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: UREG_VIBPH
Sequence: MQEYNNQDYKQPLRIGVGGPVGSGKTALLEILCKTIRDKYQIAVVTNDIYTQEDAKILTRAQALDADRIIGVETGGCPHTAIREDASMNLAAVEELAKRHKNLDLVFVESGGDNLSATFSPELADLTIYVIDVAEGEKIPRKGGPGITRSDLLVINKIDLAPYVGASLDVMEADTARMRPEKPYVFTNLKEGIGLQKIIDFIVDKGMLPKVD
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPA_HAEIE
Sequence: MSTPFKMERGVKYRDAAKTSIIPVKNIDPNQDLLKKPEWMKIKLPASSAKIESIKNGMRRHGLHSVCEEASCPNLHECFNHGTATFMILGAICTRRCPFCDVAHGKPLPPDPEEPQKLAETIQDMKLKYVVITSVDRDDLPDRGAGHFSECVKAVRELNPNIKIEILVPDFRGRVTQALEKLKDNPPDVFNHNLENVPRLYKEIRPGADYGWSLKLLREFKEMFPNIPTKSGLMVGLGETNEEILQVMQDLRDNGVTMLTLGQYLQPSRHHLPVARYVPPTEFDEFRDKANEMGFEHAACGPFVRSSYHADLQASGGLVK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPP25_HAEIF
Sequence: MKKTLAALIVGAFAASAANAAVVYNNEGSKVELGGRLSVIAEQSNNTVDDQKQQHGALRNQGSRFHIKATHNFGDGFYAQGYLETRFISHYQDNADHFDDITTKYAYVTLGNKAFGEVKLGRAKTIADDITSAEDKEYGVLNNSKYIRTNGNTVGYTFKGIDGLVLGANYLLAQARDTANPGKKGEVAAQSISNGVQVGAKYDANNIVAGIAYGRTNYRKNIIAPKQNLGRKDQVEGVLSTLGYHFSDLGLLVSLDSGYAKTKYYEQQQQQRSSPTKPRYDEKRYFVSPGFQYELMEDTNVYGNFKYERTSSDEGKKTREQAVLFGVDHKLHKQVLTYIEGAYARTKTNGKGKAETTGKEKSVGVGLRVYF
What is the function of this protein?
Forms pores that allow passive diffusion of small molecules across the outer membrane.
What are the official names of this protein?
Outer membrane protein P2, OMP P2.
What is the protein family that this protein belongs to?
Belongs to the Gram-negative porin family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: HIS2_PYRCJ
Sequence: MSCHVLERLEEVIRQRIREGNPQSYTYRLYSSGLHNVARKVGEEAVETAVAALAEGEERLVQEAADLLYHLLVLLAAKGLALADVCKELERRMK
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_LACJO
Sequence: MNYGEKSPALWDAIKSEEKRQEDTIELIASENIVSDAVREAQGSVLTNKYAEGYPGKRYYGGCQYIDKVEQLAIDYAKKLFNAEYANVQPHSGSQANMTVYNALLKPGDTILGMGMDAGGHLTHGSKVNFSGKIFNSISYDLNPETEELDFDRIRQLAIEKKPKLIIAGASAYSRIIDWQKFREIADEVGAYLMVDMAHIAGLVATGAHPSPVPIADVVTTTTHKTLRGPRGGMILSNNKELGKKIDSALFPGTQGGPLEHVIAAKAQAFYEDLQPEFTQYIDQVIKNSKAMAEEFKNSKNIRVVSGGTDNHLMIIDITKTGVTGKDAQNLLDSVNITTNKESIPGDKRSPFITSGLRIGTPAITSRGFKEPDAKEVAKIIIEVLDKPEDAGVLAEAKERVNDLVQKYPIK
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_LISMC
Sequence: MEEEFPTISLLGIDFNLSNILMITVTCVIVLLIAIICTRNLQRRPTGKQNFIEWVMDFVRGIINSNMDWKTGGRFHVLGITLLMFIFVANMLGLPFQIAINDEVWWRSPTADPIVTLTLAIMVLGLTHYYGIKMRGFKHYFVGTYFSPMKFLFPLKLVEEFANTLTLGLRLYGNIFAGEVLLTIIATQLAHMNIFVGVLAIIPALLWQGFSIFIGAIQAYIFTMLTMVYMSHKVSDEH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS15_CORJK
Sequence: MALSKEQKTETLKEFGLHETDTGSPEAQIALLTVRIRQLTEHLKYHKHDHHSRRGLLLLVGRRKGLLKYLAENNVDRYRSLIERLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.