PharMolix/UniProtQA huggingface dataset:
Protein: METE_SALTY
Sequence: MTILTHTLGFPRVGLRRELKKAQESYWAGNTTREALLAVGRELRARHWEQQKQAGIDLLPVGDFAWYDHVLTTSLLLGNVPARHQNNDGSVDIDTLFRIGRGRAPTGEPAAAAEMTKWFNTNYHYIVPEFSKGQQFRLTWTQLLEEVDEALALGHKIKPVLLGPVTYLWLGKVKGEPFDRLTLLKDILPVYQHVLAELAKRGIEWVQIDEPALVLELPQAWLDAFKPAYDALAGQVKLLLTTYFEGVTPNLDTIIALPVQGLHVDLIHGKDDVAELHQRLPVDWLLSAGLINGRNVWRADLTEKYAQINAIVGKRALWVASSCSLLHSPIDLSVETRLDTEVKSWFAFALQKCGELALLRDALNSGETAALEEWSAPIQARRHSRRVHNAAVEKRLAAITAQDSQRENPYEVRAEAQRARFKLPAWPTTTIGSFPQTTEIRGLRLDFKKGNLDANHYRTGIAEHIKQAIIEQERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPVVIGDISRPAPITVEWAKYAQSLTDKPVKGMLTGPVTILCWSFPREDVTRETIAKQIALALRDEVADLEAAGIGIIQIDEPALREGLPLRRSDWDAYLEWGVEAFRINAAVAKDETQIHTHMCYCEFNDIMDSIAALDADVITIETSRSDMELLESFEAFDYPNEIGPGVYDIHSPNVPSVEWIEALLKKAAQRIPAQRLWVNPDCGLKTRGWPETRAALANMVKAAHNLRQAK
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: CHEB1_VIBCH
Sequence: MAIKVLVVDDSSFFRRRVSEIINSESRLEVIDVAVNGKEAVEKAARLKPDVITMDIEMPVMDGISAVREIMANNPVPILMFSSLTHDGAKATLDALDAGALDFLPKKFEDIARNRDEAVTLLQQRVLSIASKKMFLRRPAAPRPAPTTSIAASSSLSQERAAATSPLGNRPSTAVSAATRFKASGKKYQLTAIGTSTGGPVALQKILTKLPVNYPHPIVLIQHMPATFTAAFASRLNSLCKIEVKEAEDGDMLRPGVAYLAPGGKQMMLDGRPGAARLRIIDGGDRMNYKPCVDVTFGSAAKIFGDKVLSMILTGMGADGREGARMLKQAGATIWAQDEESCVVYGMPQAVAKAGISTEDLPLERIAERMLVEVGLA
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 1.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOAA_STAA9
Sequence: MVEQIKDKLGRPIRDLRLSVTDRCNFRCDYCMPKEVFGDDFVFLPKNELLTFDEMARIAKVYAELGVKKIRITGGEPLMRRDLDVLIAKLNQIDGIEDIGLTTNGLLLKKHGQKLYDAGLRRINVSLDAIDDTLFQSINNRNIKATTILEQIDYATSIGLNVKVNVVIQKGINDDQIIPMLEYFKDKHIEIRFIEFMDVGNDNGWDFSKVVTKDEMLTMIEQHFEIDPVEPKYFGEVAKYYRHKDNGVQFGLITSVSQSFCSTCTRARLSSDGKFYGCLFATVDGFNVKAFIRSGVTDEELKEQFKALWQIRDDRYSDERTAQTVANRQRKKINMNYIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: COAD_STRGC
Sequence: MSDKIGLFTGSFDPMTKGHVDLIERASRLFDKLYVGIFYNREKSGFFTIEARERIVKEALQHLDNVEVITSQNELAVTVARRLGAKAFVRGLRNSQDLDYEADMTFFNRELAGELETIFLLSKPAYQHISSSRIRELIAFQQDIADYVPQSVIKELERRTYEKN
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEUM_SERCA
Sequence: TKQVEKNEDGDQKIEQDGIKPEDKAHKAATKIQASFRGHITRKKLKGEKKGDAPASETDAADKKEEGPAGGAAENKESEAPAATEAAAADSAQQEEGSKDSSAPAEEKKGDGAADTGSEQPAPQAATPAASSEEKTAAAAAPERESTPKASTDNSPSLKADEAQDKEEPKQADVPAADTTATTTPAAEDATAKATAQPQMETVESSQTEEKTDAVEETKPTESAQQEEMKEEESKADQENA
What is the function of this protein?
This protein is associated with nerve growth.  It is a major component of the motile 'growth cones' that form the tips of elongating axons.  Plays a role in axonal and dendritic filopodia induction (By similarity).
What are the official names of this protein?
Neuromodulin, Axonal membrane protein GAP-43, Growth-associated protein 43.
What is the protein family that this protein belongs to?
Belongs to the neuromodulin family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, growth cone membrane; Peripheral membrane protein; Cytoplasmic side. Synapse. Cell projection, filopodium membrane; Peripheral membrane protein.
Protein: RK2_ZYGCR
Sequence: MGIRSYKAYTPGTRNRSVSQFEEIVQSKPEKQLTSGQHRKKGRNNRGVITSRHRGGGHKRLYRHIDFKRDKYGMLGRIVSIEYDPNRNARICLISYQDGEKRYILHPRGISIGDQILSDTHAPISPGNALPLTNMPLGTTIHNIELQPGKGGQVARAAGAIAKIIAKEGKFATLRLPSGEVRLVLQQCLATIGQVGNVDANNQSIGKAGSKRWLGRRPTVRGVVMNAADHPHGGGEGRAPIGRKRPLTPWGRPTLGRKSRSRHKYSEALILRRRKNA
What are the official names of this protein?
50S ribosomal protein L2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: H2Y01_CYRHA
Sequence: MKVTLIAILTCAAVLVLHTTAAEELEAESQLMEVGMPDTELAAVDEERLFECSVSCEIEKEGNKDCKKKKCRGGRKCKFNMCVKV
What is the function of this protein?
Postsynaptic neurotoxin.
What are the official names of this protein?
U4-theraphotoxin-Hhn1q, U4-TRTX-Hhn1q, Hainantoxin-II-25, HNTX-II-25.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 12 (Hwtx-2) family. 02 (Hwtx-2) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CDIN1_XENTR
Sequence: MLLSKAQYDEIALFITTLRPTRQCMRRLKERFPCQSQSTLLSIFSQEYQKLIKRTHAKHHTPEAIEMYYARYLNEVARDPTVPILLELANEVDFSPALIARTVLERFLQDHDGQPPTKPILSSMLRDPSLIPDPVLANQVHLCIINDCCNGPLVDGIKHAIGHEHEVLLRQKLKEHNLAFLDEDQLRLKGYDKTPDVILEVPVAVDGHVIHWIESKASFGDEASHNTYLHDQFWSYWNRFGPGLVIYWYGFIEELDCNRERGILLKDGFPESLVTLGSCMAQNAEHGQHTKSRLSETHQETQS
What is the function of this protein?
May play a role in erythroid cell differentiation.
What are the official names of this protein?
CDAN1-interacting nuclease 1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Mainly nuclear.
Protein: CDC10_ENCCU
Sequence: MKNIPTIVRNLGTINIRNNVGFSSVPDQVRESSMVKGFELNVLVVGRRGLGTSTLINSIFAAPLVDKKRTNNITATRNEIVENDISLEISIVTYHEANISPVLDYINAMNREYFDNEQGLYKAFKDNRVHVCLYLLPSDTLTDQEIKNMYELSQSCNLVPIIPKADMYTPDELADVKENVRQILSENNIFSFVPYLNENDGDLTEEVADIVGCMPFAVIASETMYEHGGEIIRGRKYPWGFINIDQEESNDFKRLQRLLIYTNLDELTMKTNHLFYNNYRKKIFEIENDCGAMKEARYLRLRTETIRILNDKYESRINALRKEEEEMERFYSEKIREMNDKMGEISKQVEKSLHVE
What is the function of this protein?
Septins are GTPases involved in cytokinesis.  The septins localize to the site of cleavage and act as a structural scaffold that recruits different components involved in diverse processes at specific stages during the cell cycle.  Septins are also involved in cell morphogenesis, chitin deposition, cell cycle regulation, cell compartmentalization and spore wall formation (By similarity).
What are the official names of this protein?
Cell division control protein 10.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
Protein: RL321_ENTFA
Sequence: MAVPARRTSKTKKRLRRTHEKLKSPEISFDENLGDYRKSHHVSLKGYYGGKKVMDKK
What are the official names of this protein?
50S ribosomal protein L32-1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: LEPA_TROWT
Sequence: MTDRVLPEQIRNFGIIAHVDHGKSTLADRILQLTGAVSDRDMREQYLDRLYIERERGITIKSQAVTLQWDCDATQYVLNMVDTPGHVDFTYEVSRSLAACEAAVILVDATQGVEAQTLANLHLAIENNLLIIPVLSKVDLPSADVEGATLELSEVLECRVEDVMHVSGKTGYGVKELLDLIVRKAPPPKGDVTSAPRALIFDSIYDSYRGVVTYVKMCDGTIRVGDKIRMMSTGAEHTLLEVGVSNPEPQSRHSLSVGEVGYFITGVKDVRKSRVGDTITTDTHTATVPLPGYSNPKPMVFSGIYPLNGNEYSALREGLDRLKLSDASIVYTPETSAALGFGFRCGFLGLLHMEIVSERLNREFGLATISTAPSVAYEITPDGEKTLVVMNPSDFPSGKIKEIKEPTVKVSILSPKEYIGSIMELCQARRGVMQGIEYFGSVRAELIYVMPLAEIVFDFFDSLKSRTKGYASFDYNPEGSQPADLVKVDILLQGNKVDAFSAIVHSSKAYSYGSSISKRLSELIPRQQFEVPIQAAIGSRVVARETIRAVRKDVVAKCYGGDITRKRKLLEKQKQGKARMKLIGRVEVPQEVFVATLSSYK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PVDQ_PSE14
Sequence: MIISRPLCGFVFAGLSFAVILPAQALVAADNQAARAEIRRTGFGVPHIVAANERGLGYGIGYAYAQDNLCLLANEVVTVNGERSRYFGPDKATLEQRSNMASDLLFKWLNTPEALADFWKAQPPEIRQLMQGYVAGYNRSLDEQKTKGLPRPCAADWVRPISTDDLLRLTRRLLVEGGVGQFTEAFAGAKPPSAQKPLQVDSQQVQALQLAAVRNQRFALERGSNAVAVGHELSANGRGMLLANPHFPWGGGMRFYQMHLTIPGKLDVMGAALPGLPLINIGFNRHLAWSHTVDTSKHFTLHRLQLDPKDSTRYLLDGKSIAMGQQQVSVEVKQPDGSLKDVPRIIYSSKFGPVVQWPGKLDWDDKFAFSLRDANLENDRVLQQWYSMDKADSLKAFQDSLHKIQGIPWVNTLAVDAKGQALYMNLSVVPNVDAAKLAKCSDPRIGTELIVLDGSRSECNWDISAEAAQAGIYPSSRQPQLLRSDFVQHSNDSAWMVNPAAPLKGFSPLISQDGQPLGQRARFALDRLGSLQQAGKVSAENLQAMVMDNEVYQAGQVLPDLLKFCASELGDDVARLTPLCAALKAWDGRADLNSGIGFVYFQRIMTSMQGVASRWRVVFDPQNPIHTPSGLAIENPQVASALRAAMLAAVDEVAKAGLSPESKWGDIQVSSLSGKPIPIHGGPAGLGVYNAMQTIAGKDGKREVVSGTSYLQVVTFDEQGPRAQGLLAFSESSNPQSAHSSDQTEAFSKKQWSELPFTEQQIKADPAYQVQVISEEGSR
What is the function of this protein?
Catalyzes the deacylation of acyl-homoserine lactone (AHL or acyl-HSL), releasing homoserine lactone (HSL) and the corresponding fatty acid.  Possesses a specificity for the degradation of long-chain acyl-HSLs (side chains of 11 to 14 carbons in length) (By similarity).
What are the official names of this protein?
Acyl-homoserine lactone acylase PvdQ, AHL acylase PvdQ, Acyl-HSL acylase PvdQ.
What is the protein family that this protein belongs to?
Belongs to the peptidase S45 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: LZTR1_MOUSE
Sequence: MAGSGGPIGSGALTGGVRSKVAPSVDFDHSCSDSVEYLTLNFGPFETVHRWRRLPPCDEFVGARRSKHTVVAYKDAIYVFGGDNGKTMLNDLLRFDVKDCSWCRAFTTGTPPAPRYHHSAVVYGSSMFVFGGYTGDIYSNSNLKNKNDLFEYKFATGQWTEWKIEGRLPVARSAHGATVYSDKLWIFAGYDGNARLNDMWTIGLQDRELTCWEEVAQSGEIPPSCCNFPVAVCRDKMFVFSGQSGAKITNNLFQFEFKDKTWTRIPTEHLLRGSPPPPQRRYGHTMVAFDRHLYVFGGAADNTLPNELHCYDVDFQTWEVVQPSSDSEVGGAEMPERASSSEDASTLTSEERSSFKKSRDVFGLDFGTTSAKQPVHLASELPSGRLFHAAAVISDAMYIFGGTVDNNIRSGEMYRFQFSCYPKCTLHEDYGRLWEGRQFCDVEFVLGEKEECVQGHVAIVTARSRWLRRKIVQAQEWLAQKLEEDGALAPKEAPGPAVGRARPPLLRVAIREAEARPFEVLMQFLYTDKIKYPRKGHVEDVLLIMDVYKLALSFQLCRLEQLCRQYIEASVDLQNVLVVCESAARLQLGQLKEHCLNFIVKESHFNQVIMMKEFERLSSPLIVEIVRRKQQPPPRTPSDQPVDIGTSLIQDMKAYLEGAGSEFCDITLLLDGQPRPAHKAILAARSSYFEAMFRSFMPEDGQVNISIGEMVPSRQAFESMLRYIYYGEVNMPPEDSLYLFAAPYYYGFYNNRLQAYCKQNLEMNVTVQNVLQILEAADKTQALDMKRHCLHIIVHQFTKVSKLPTLRLLSQQLLLDIIDSLASHISDKQCAELGADI
What is the function of this protein?
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates ubiquitination of Ras (K-Ras/KRAS, N-Ras/NRAS and H-Ras/HRAS) (PubMed:30442762).  Is a negative regulator of RAS-MAPK signaling that acts by controlling Ras levels and decreasing Ras association with membranes (PubMed:30442762).
What are the official names of this protein?
Leucine-zipper-like transcriptional regulator 1, LZTR-1.
What is the protein family that this protein belongs to?
Belongs to the LZTR1 family.
What are the subcellular locations of this protein?
Endomembrane system. Recycling endosome. Golgi apparatus.
Protein: CASP1_STRHE
Sequence: MEKNKSTAIEIAESSKESKGKAPLLAAAVGHDRAAGYKRGVSIFDLFLRISAATAALAATIVMGTTEQTLPFFTQFFQFRAQYDDLPTFTFFVVGMAIVTGYLILSVPFSIVCIARPVAIGPRFLLIVGDTLKAVLATSAAGSSAAIVYLAHNGNSDANWLDICQQFNDFCQRVSGAVVAAFVAVVLLIFLIVLSAMALRKN
What is the function of this protein?
Regulates membrane-cell wall junctions and localized cell wall deposition.  Required for establishment of the Casparian strip membrane domain (CSD) and the subsequent formation of Casparian strips, a cell wall modification of the root endodermis that determines an apoplastic barrier between the intraorganismal apoplasm and the extraorganismal apoplasm and prevents lateral diffusion (By similarity).
What are the official names of this protein?
Casparian strip membrane protein 1, ShCASP1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Very restricted localization following a belt shape within the plasma membrane which coincides with the position of the Casparian strip membrane domain in the root endodermis.
Protein: MOC2A_USTMA
Sequence: MSNGTPSVRVLYFASARTTIGHSSETISLPTTPFPLASLITLIANKYSSRGAEAVLRTCRWSVDNTLIEIDELIEWTLHGREEVAAIPPVSGG
What is the function of this protein?
Acts as a sulfur carrier required for molybdopterin biosynthesis.  Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group.  In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by UBA4.  After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin.
What are the official names of this protein?
Molybdopterin synthase sulfur carrier subunit, Molybdenum cofactor synthesis protein 2 small subunit, Molybdenum cofactor synthesis protein 2A, MOCS2A, Sulfur carrier protein MOCS2A.
What is the protein family that this protein belongs to?
Belongs to the MoaD family. MOCS2A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENGB_SYNC1
Sequence: MQIKSAEFIKSAAKPVGYPPGDLPEVAFAGRSNVGKSSLINVLVNRRGLVRTSSTPGRTQLLNFFEVNQHFMLVDLPGFGFAKVPVSVKKAWGRMTRTYLEERTNLKAVVLLFDIRREPRDEELQLLDWLEELNIPTIPVITKVDKVTKNRRRAQIRPILEATGLPQEAFSFFSALTREGREDILQRLDVALSDVEDEFGIDVPESE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: TRUB_THEVO
Sequence: MIEEIQKLNGFIVIDKPQGPTSHQVDYWVRQILGTEKVGHIGTLDPNVTGVLVMAIGKAVRLIDVVHEKPKEYVGVMRFHSDISEEEVREVFRKFTTRIYQLPPVRSAVSRKVRIKTIYELDMIEKKDKIVLFHVKCESGTYIRTLCTDIGYVSGKGGQMVDLRRISTGPFKEDIAITLQDLQAYVDLAKEGKDELFRSHFLDMTYAFIDYPKIVAKKSAVENIAHGSDLYVGGVKLIDGNFQKGDRVCVLSEDNELLGTGIARCDSSNLFMKVVDFDHIFVEAKHGKGDVVRDREKDVQRPGQQVHRNIRDAAHGPDSRTGRGRKETGPQIAPNRVRKLQNKTGVHRRPGSH
What is the function of this protein?
Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
Probable tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
Protein: RAF2_ARATH
Sequence: MFSLKSLISSPFTQSTTHGLFTNPITRPVNPLPRTVSFTVTASMIPKRSSANMIPKNPPARQQLYQPFRPPSSPIPTQFRSLDSAGKIEILAGRMALWFEYAPLISSLYTDGFTPPTIEELTGISSIEQNRLIVGAQVRDSILQSIHEPELISAFDTGGAELLYEIRLLSTTQRVAAATFIIDRNIDSKGAQDLARAIKDYPNRRGDVGWLDFDYNLPGDCLSFLYYRQSRENKNPSDQRTSMLLQALGVAESEKAKNRLNTELYGDKEAEKEKEKKKKEEEVKAIRIPVVRLKFGEVAEATSVVVLPVCKAEEGEKKILEAPMEIIAGGDFKVVEAEKGWKRWVVLPSWNPVAAIGKGGVAVSFRDDRKVLPWDGKEEPLLVVADRVRNVVEADDGYYLVVAENGLKLEKGSDLKAREVKESLGMVVLVVRPPREDDDDWQTSHQNWD
What is the function of this protein?
Required for assembly or stability of RuBisCO.  Acts at a postchaperonin step to fold and/or assemble the large subunit (rbcL) into RuBisCO.  RAF1 brackets an rbcL dimer (rbcL(2)), leading to rbcL(8)-RAF1(4) complex formation.  In the next step, RBCS displaces RAF1, thus resulting in holoenzyme formation.
What are the official names of this protein?
Rubisco accumulation factor 1.2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the RAF family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RPOA_CUCSA
Sequence: MVREKIRVSTRTLKWKCVESRADSKRLYYGRFILSPLMKGQGDTIGIAMRKALLGEIEGTCITRAKSEKIPHEYSTIVGIQESVHEILMNLKEIVLRSNLYGTRDASICVKGPGCVTAQDIILPPSVEIVDNTQHIANLMEPINLCIELKIERNRGYHIQTPNNFQDASYPMDAIFMPVRNVNHSIHSYVNGNEKQEILFLEIWTNGSLTPKEALHEASRNLIDLFIPFLHAEEEKENFHLKNNKKKVTLPLFTFHEKLAKLRKKKKEIALKYIFIDQSELPPRIYNCLKRCNIHTLFDLLNNSPDELMKIKHFRIEDVKHILDILEMEKNFA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CDK3_CONMS
Sequence: MPKLAVVLLVLLILPLSYFDAAGGQVVQGDRRGNGLARYLQRGDRDVRECQVNTPGSSWGKCCMTRMCGTMCCARSGCTCVYHWRRGHGCSCPG
What is the function of this protein?
Alpha-D-conopeptides act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.  This toxin specifically blocks mammalian neuronal nAChR of the alpha-7/CHRNA7 (IC(50)=0. 12 nM), alpha-3-beta-2/CHRNA3-CHRNB2 (IC(50)=1. 08 nM), and alpha-4-beta-2/CHRNA4-CHRNB2 (IC(50)=4. 5 nM) subtypes.  Has no effect on alpha-3-beta-4/CHRNA3-CHRNB4, alpha-4-beta-4/CHRNA4-CHRNB4 and alpha-1-beta-1-epsilon-delta/CHRNA1-CHRNB1-CHRNE-CHRND subtypes of nAChRs.
What are the official names of this protein?
Alpha-conotoxin Ms20.3, Conopeptide alpha-D Ms.
What is the protein family that this protein belongs to?
Belongs to the conotoxin D superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ADC2_RHILO
Sequence: MHQDTVRATAFAMPLTSPAYPVGPYRFRNREYLIITYRTDPKKLRSLVPEPLELSEPLVKFEFIRMPDSTGFGNYTESGQVIPVTFRGRKGSYTHCMFLNDHPPIAGGRELWGFPKKLATPTLRTETDTLVGTLDYGPVRVATATMGYKHEAADLSAVRSSLAEPNFLLKIIPHVDGTPRICELVEYHLEDVDLRGAWAGPASLNLWSHALAPVAELPVLEVVSAMHIVADLTLALGKVVHDYLPKSEPRDLKGRSHAFAE
What is the function of this protein?
Catalyzes the conversion of acetoacetate to acetone and carbon dioxide.
What are the official names of this protein?
Acetoacetate decarboxylase 2, AAD 2, ADC 2.
What is the protein family that this protein belongs to?
Belongs to the ADC family.
Protein: ILVC_ESCF3
Sequence: MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVGCGAQGLNQGLNMRDSGLDISYALRKEAITEKRASWRKATENGFKVGTYEELIPQADLVVNLTPDKQHSDVVRTVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKLVEEGTDPAYAEKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADWANDDKKLLTWREETGKTAFETAPQYEGKIGEQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFSYACVPLLKPFMAELQPGDLGKAIPEGAVDNAQLRDVNEAIRSHAIEQVGKKLRGYMTDMKRIAVAG
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: EIS1_YEAS6
Sequence: MSLISAVEDRDIHNIGKTSGGGSRTSSITSSKKSLKHGSKSLRKPKVYQTTGELLSREALYKAKLKYGVYQSPAQSYSIGVSDAHAASDKAANLAHDNQTTVEAYKRMFIDPNATKAASKMGPKVVRNNSITSATSKTSKESQTKRKSKESPGAAASKAYSMTMETTSLSSQTNSRSYSITSASSVLSGASGSFNSTVNPKPKTLNLEKVLVGAEKKAESRIKERWEPEKTNFQYGVKTDEHGNLNQFSFSNEMMNNIMAKVDAPKAQDLQKVKKVSAEKEAKSMKFALGAANAVKDMHPGEDIDKSIALKAQKRETYLSQLTSQQVLTLARANVDRQLDIIEKSDMHRKLFTNMEYNKAAVAVAQSNHQKKTEFHNKINMGGGLFLSPEDITKIASGLISPVLGEVSERAEAQRAMDEEIAERTEAYNKSLNEWETMERSIISNDAKVLTTTANRHQTEKKTSQEKIKASFDALVARMDTKVAERETLLEDTKSKEIEFKKQMQQELKDEKARLDQDLEEWGKKCEQDITEARKEQEELLKPYHDDLANAEAEHKTLVEERDEINAEISRLQDAIVDHKRKISGYGNDLDAQKNRNIREDDKLLELGQTKESLESHLNDDVIILANKAKEQAELSTKEARLKQLEVDSLINERKSELNATEIELKKEKLNLLEAMKDVASARGDDKIDEEKVKKLIGMTSEEYLTQNKSVEKNVEDLPTQLEKIEEGDELKKEEIVGAETKNSGGDGVPVSTAAKEATETSSAVQTKEPEEKISIGNKSSGKEDANDCKSAEHSKEISVSQKAGNNKSLGVSPDSLEHTFSGFSQGSSIEDDQDAISNQEKK
What is the function of this protein?
Required for normal formation of eisosomes, large cytoplasmic protein assemblies that localize to specialized domains on plasma membrane and mark the site of endocytosis.
What are the official names of this protein?
Eisosome protein 1.
What is the protein family that this protein belongs to?
Belongs to the EIS1 family.
What are the subcellular locations of this protein?
Cytoplasmic granule. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes at the eisosomes.
Protein: RIBL_THEGJ
Sequence: MSGPSKGRKIRVLVGGVFDILHVGHVHFLKQAKELGDELVVIVAHDETVRRNKRRNPINPAEDRAELLRAIRYVDEVYIGSPGGIDFELVRRINPDVIAIGPDQNFNCEKLKEELKRHGIEAEVIRVPYLYKSDRAKTTKIIRRIVEEFCE
What is the function of this protein?
Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
What are the official names of this protein?
FAD synthase, FMN adenylyltransferase, Flavin adenine dinucleotide synthase.
What is the protein family that this protein belongs to?
Belongs to the archaeal FAD synthase family.
Protein: GLGA_RHIEC
Sequence: MKVLSVSSEVFPLIKTGGLADVSGALPIALKAFGVETKTLLPGYPAVMKVIRDPVVRLEFPDLLGERATVLEVDHEGLDLLVLDAPAYYDRPGGPYLDPLGKDYPDNWRRFAALSLAASEIGAGLLPGWRPDLVHTHDWQAALTSVYMRYYPTPELPSVLTIHNIAFQGQFGSEIFPGLRLPDHAFAIDGVEYYGTTGFLKGGLQTAHAITTVSPTYADEILTPEFGMGLEGVIATRIDDLHGIVNGIDTDVWNPATDPVVHTHYGPTTLKNREENRRSIAEFFHLDNDDAPIFCVISRLTWQKGMDIVANVADRIVAMGGKLVVLGSGEAALEGALLASASRNPGRIGVSIGYNEPMSHLMQAGCDAIIIPSRFEPCGLTQLYALRYGCVPIVARTGGLNDTVIDANHAALAAKVATGIQFSPVTETGMLQAIRRAMHFYADRKLWTQLQKQGMKSDVSWEKSAERYAALYSSLVSKGM
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: NT5D3_XENLA
Sequence: MRGYLNSNYKEVKRSINELDPSISSNLLNPDAIFANNEMSLEDIEVYGFDYDYTLAFYSKHLHTLIFNTARDILINEHRYPKEIQRYEYDPNFAIRGLHYDVHKALLMKIDSFHYIQLGTVYRGLNVVPDSEVIEMYEGSHVPLEQMSDFYGKSSEGNTMKQFMDIFSLPEMTLLCCVNEYFLKNNIDYEPVHLYKDVKEAIRDVHVKGILYRAVEADIERYICYGERTQAVLSKLSNHGKKMFLITNSPSSFVNKGMNFIVGKDWRDLFDVVIVQADKPNFFNDKRRPFRKVAERGILLWDKIHHLEKGQTYKQGNLFEFLKLTGWRGSKVLYFGDHIYSDLADLTLKHGWRTGAIIPELKSEIEIMNTSHYIKTMAWLQGLTGLLERMQVYRDAESQMVLQDWIKERQETRDLTKTMFNRQFGSIFRTDHNPTYFLRRLSRFADIYMESLSSLLNYDLHHTFYPKRTPLQHELPVCSEQQYANTFRIPLGRETAPIK
What are the official names of this protein?
5'-nucleotidase domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the 5'(3')-deoxyribonucleotidase family.