PharMolix/UniProtQA huggingface dataset:
Protein: AIM21_YEAS8
Sequence: MPSEVTPKVPERPSRRKTSELFPLSGSESGDIKANSEPPTPAGTPNVPTRRPILKAKTMTSFESGMDQESLPKVPLQRPVRRSTTEELNNVMNNTSKELEEIESLISKHNIHNVSRKKSPTSVEEGKVAAIHQNGQRSASDNKTSTNPSPLEKNEHEGAEGNESAISPSNLVNKSNNEVTEHSDSEDLTEKQKVHAALDNEAGDRSHFEEKLIPGDMKVQVDVSKDVEEGSLNALPPSGITESDDKAEKFTKHPESSLEELQKHQEQQEEKIFQNPTDEESTTSLNEKQEGKDNMEVNSQPQGPSDTETVIAATSSNVPSQIASEEENDVPVIPRSRPKKDFEAHVQKEELPNTQEKRVSEECDSTLISTEEESKIPKIPSERPKRRAPPPVPKKPSSRIAAFQEMLQKQQQQDLHNNGNSSATTASADIAKKHTDSSITSDTTKADFTSKLNGLFALPGMVNPGQLPPSLEKKLSSPDTESKLGPQDQSQAKTGPLGGTRRGRGPRGRKLPSKVASVEKIEEDDNTNKIEIFNNWNVSSSFSKEKVLIDTTPGEQAERALDEKSKSIPEEQREQSPNKMEAALCPFELDEKEKLPANAESDPLSQLPQTNTVGNRKAISEESLSPSEAIANRDQNDTTEIQEQQMEDQMEVDMERELSGGYEDVDSALHSEEASFHSL
What is the function of this protein?
Involved in mitochondrial migration along actin filaments.
What are the official names of this protein?
Altered inheritance of mitochondria protein 21.
What is the protein family that this protein belongs to?
Belongs to the AIM21 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, actin patch. Note=Cortical actin patches. Localizes at the shmoo tip.
Protein: CDPKR_ORYSJ
Sequence: MGNVCIGPRRNFAKNGLLGILRPRHAAPSSPSQPTTTSRSIPVVLPSAPSSKPPPPTQTAPPVPVVISEPPPPQPQPEPQPAAPSQPPPPQEQPSPPPPASSNTTQQPPPPQQRQQSRAKKPAHIKRISSAGLQVESVLRRKTENLKDKYSLGRKLGQGQFGTTYLCVDKANGGEYACKSIAKRKLLTDEDVEDVRREIQIMHHLAGHPNIISIRGAYEDAVAVHVVMELCAGGELFDRIVRKGHYTERQAAGLARVIVAVVESCHSLGVMHRDLKPENFLFVGNEEDAPLKTIDFGLSMFFRPGEVFTDVVGSPYYVAPEVLKKSYGQEADVWSAGVIIYILLCGVPPFWAETEQGIFEQVLHGTLDFESDPWPNVSDGAKDLLRKVLVRDPKKRLTAHEVLCHPWLQMSGSAPDKPLDSAVLSRLRQFSAMNKLKKMALRVIAENLSEEEIAGLKEMFKMMDTDNSGQINYEELKAGLERVGANMKESEIYQLMQAADIDNSGTIDYGEFIAATLHLNKVEREDHLYAAFQYFDKDGSGYITSDELQQACDEFGIEDVRLEDMIGEVDQDNDGRIDYNEFVAMMQKTTTGFGKKGGHNFSGFRDALKSHS
What is the function of this protein?
May play a role in signal transduction pathways that involve calcium as a second messenger.
What are the official names of this protein?
Calcium-dependent protein kinase 27, OsCDPK27, OsCPK27.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily.
What are the subcellular locations of this protein?
Membrane; Lipid-anchor.
Protein: RL5_METMP
Sequence: MSFQEVWEKEPMKKPRIQKVTVNFGVGEAGDRLTIGAKVIEELTGQSPVRTLAKQTNPAFGIRKKLPIGLKVTLRGKKAEEFLKNAFTAFKACGKTLFASSFDQVGNFSFGVPEHIDFPGQKYDPSVGIYGMDICVTFEKSGYRVKSRKVKRSHIPEKHLVTKDEAIEYIQAKFDTEVVRE
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: APT_RHOPT
Sequence: MTPEFANDLKASVRAIPDYPKPGIIFRDITTLLGEPRAFRRAIDELVQPWAGSKIDKVAGIEARGFIIGGAIAHQVSSGFVPIRKKGKLPHTCVSMEYALEYGTDKIEVHVDAITPGERVILVDDLIATGGTAEGAIKLLRQIGAEVVAACFVIDLPELGGAAKIRAMGVPVRTLVAFEGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ESRP1_XENTR
Sequence: MTAVSPDYLVVLFTTTAGANGSKLGSDEKEVIQLLWKVINLANKKVGELHEVTVRPDHLELTEECKEITRIEADSLYVAPQLEQALQQFNQSVGNELNIGVGTSFCICTDGQLHIRQVLHPEASKKNILLPECFYSFFDLRKEFLKCCPGSSDTNELDVHAMASYLGFEKKSTRYRYGASEVDDMGDIIVTLISEPYNYKFSDPERVNYKFESGTCSKLEIIDDNTIIRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGNRYIEVYKATGEDFLKIAGGTSNEVAQFLSKENQVIVRMRGLPFTATAEEVLAFFGQQCPVTGGKEGILFVTYPDNRPTGDAFVLFACEEYAQNALKKHKELLGKRYIELFRSTAAEVQQVLNRYSSAPLIPLPTPPIIPVLPQPFIPPVNVRDCIRLRGLPYAATIEDILEFLGEFSADIRTHGVHMVLNHQGRPSGDSFIQMKSADRAYLAAQKCHKKTMKDRYVEVFQCSAEEMNFVLMGGTLNRNGLSPPPCKLPCLSPPSYTFPAQAAVIPTEAAALYQPSLLLNPRSLQPSAAYYPAGAQLFMNYTAYYPSPPGSPSSLGFFPASASVSSIPPHNTGAMVRMQGLAYNSGVKEILNFFQGYQYSPEDGLLPVNDQARALLTHPKEWVCI
What is the function of this protein?
mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms.  Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of fgfr2.  Acts by directly binding specific sequences in mRNAs.  Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of fgfr2 (By similarity).
What are the official names of this protein?
Epithelial splicing regulatory protein 1, RNA-binding motif protein 35A, RNA-binding protein 35A.
What is the protein family that this protein belongs to?
Belongs to the ESRP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: R27AA_ARATH
Sequence: MQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGAKKRKKKTYTKPKKIKHTHKKVKLAVLQFYKVDGSGKVQRLKKECPSVSCGPGTFMASHFDRHYCGKCGTTYVFKKADEE
What is the function of this protein?
Ribosomal protein RSP27a-1 is a component of the 40S subunit of the ribosome.
What are the official names of this protein?
Ubiquitin-40S ribosomal protein S27a-1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
What are the subcellular locations of this protein?
[Ubiquitin]: Cytoplasm. Nucleus.
Protein: GCST_CHLP8
Sequence: MKKTALSAWHEGAGAKMIDFGGFLMPVQYSGIIAEHKAVREAAGLFDVSHMGNFYVRGERALEFLQYVTTNDLGKIVDGQAQYTLMLYPDGGIVDDLIIYRVSADTFFLIVNASNCEKDFAWLSDHVGGFEGVTLENRTSELSLIALQGPKAFEVLGRVFPEAGLDKLASFHFATVPFGGAEAMVARTGYTGEAGVEICLPNEEAEALWTALMAAGKNDGIQPIGLGARDTLRLEMGYSLYGHEIDQTVNPLEARLKWVVKMDKPNFIGKQACQQVELDPRKSVVGFSLDGRAIPRQHFKVYNSDKQEIGEVCSGTVSPTLQEPIGTASLLRDYAKTGTPIFVEIRGTFQPGTVRRLPFVHADRP
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: MOAC3_MYCTO
Sequence: MNDHDGVLTHLDEQGAARMVDVSAKAVTLRRARASGAVLMKPSTLDMICHGTAAKGDVIATARIAGIMAAKRTGELIPLCHPLGIEAVTVTLEPQGADRLSIAATVTTVARTGVEMEALTAVTVTALTVYDMCKAVDRAMTITDIRLDEKSGGRSGHYRRHDADVKPSDGGSTEDGC
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase 3, Molybdenum cofactor biosynthesis protein C 3.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: HSPQ_SALTI
Sequence: MIASKFGIGQQVRHSLLGYLGVVVDIDPEYSLDEPSPDELAVNDELRAAPWYHVVMEDDDGQPVHTYLAEAQLRSEMRDEHPEQPSMDELARTIRKQLQAPRLRN
What is the function of this protein?
Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress.
What are the official names of this protein?
Heat shock protein HspQ.
What is the protein family that this protein belongs to?
Belongs to the HspQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YL1_MDBVW
Sequence: MFGDMIELFKPKKELPAVRKCSVINGDVKTFGKAYNDIKLAGKGSKLLKQTSDFSDESSRSDSSSVTNENEVSKAANTRLLHLPMPVNKIKAIALEHELLIKMREIFSEAAKLLESYVALRASVN
What are the official names of this protein?
Uncharacterized protein L1.
Protein: TIG_BORAP
Sequence: MILSKDIRLLPGSKVEAVIRVSKNIIQEKYNSLLQDYSSRLKIQGFRIGKVPISIIEKKYSEGLRATVLEEVINNSLKEFFKEEPKRPLSYASPTIKEENLRLNLDKDFEFTFVYETYPEFKVPNIDDIDIKVEVPEVFIDDSDIDNEIKSLQIENSIIIEDEEGVVKKDSIVKVDFVELDDLLNEIVSTKRQDFVFTVGKSETYYDFDRDVIGMRINEERVIEKSYITDYKFEELAGSLKKLKIKIKSIKKRDLPLIDDEFAKDISERYNTLDDLKNFIRSKILSLVEEKKEALKLNKFFSTISEKLEIDIPRSMIEAEIEIAFKDAKRQNKMSLEEFKSMFYSSGYNGSDSLKDEILSNLKSKLIIQKMVDLDPIKVTENDLKDEMVRQSENSGVSYEEIKKFYEDQNLIFYLKDDIKRKIVEKKILASLKEVKGKQVSFKDFVNYKICE
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: RL10_CAUSK
Sequence: MDRAQKQESIEALKSVFADAGAVVVTHYMGMTVAEMTELRSRLRKEDATFQVVKNTLVQKALDGSIGEAGDALFTGPVAIAFGSDPVSAAKIVTQYAKENDKLKLVGGILGQTTVLDEAAVRALATLPSLDQIRGKLIGLIQAPATKIAGVLQAPAGQLARVLNAYATKDAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: PAGR_BACAN
Sequence: MTVFVDHKIEYMSLEDDAELLKTMAHPMRLKIVNELYKHKALNVTQIIQILKLPQSTVSQHLCKMRGKVLKRNRQGLEIYYSINNPKVEGIIKLLNPIQ
What is the function of this protein?
Represses the expression of the pagA and atxA genes.
What are the official names of this protein?
Transcriptional repressor PagR, Protective antigen repressor.
Protein: ZDH11_HUMAN
Sequence: MDTRSGSQCSVTPEAILNNEKLVLPPRISRVNGWSLPLHYFQVVTWAVFVGLSSATFGIFIPFLPHAWKYIAYVVTGGIFSFHLVVHLIASCIDPADSNVRLMKNYSQPMPLFDRSKHAHVIQNQFCHLCKVTVNKKTKHCISCNKCVSGFDHHCKWINNCVGSRNYWFFFSTVASATAGMLCLIAILLYVLVQYLVNPGVLRTDPRYEDVKNMNTWLLFLPLFPVQVQTLIVVIIGMLVLLLDFLGLVHLGQLLIFHIYLKAKKMTTFEYLINNRKEESSKHQAVRKDPYVQMDKGVLQQGAGALGSSAQGVKAKSSLLIHKHLCHFCTSVNQDGDSTAREGDEDPCPSALGAKARNSRLICRRLCQFSTRVHPDGGSMAQEADDAPSISTLGLQQETTEPMKTDSAESED
What is the function of this protein?
Has also a palmitoyltransferase activity-independent function in DNA virus-triggered and CGAS-mediated innate immune response (PubMed:28331227).  Functions as an adapter that recruits IRF3 to STING1 to promote the activation of that key transcriptional regulator of type I interferon (IFN)-dependent immune response (PubMed:28331227).
What are the official names of this protein?
Palmitoyltransferase ZDHHC11, Zinc finger DHHC domain-containing protein 11, DHHC-11, Zinc finger protein 399.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SYY_FLAPJ
Sequence: MKNLVEELKWRGLFHDMMPGTEEQLTKESTTAYIGFDPTADSLHIGSMVQIILLVHLKNFGHKPIALIGGATGMIGDPSGKSDERNLLDEATLNKNVAGIKAVLSSFLDFNTTNANAPILVNNYDWMKDFSFIDFARDIGKRITVNYMMSKDSVKKRLGAEGEGMSFTEFTYQLIQGYDFQYLYKNHNCLLQMGGSDQWGNITTGTELVRRMGGEGAKAYALTTPLITKADGSKFGKSEGGNVWLTADKTSVYKFYQFWLNTSDDDAEKYIKIFTFLDKNTIDGLIEEHKTAPHLRVLQRKLTEEITILVHGKEELEKAIKASNILFGNSTSNDLKGLDAATFLEIFDGVPQAEISKTDIEAGINIVEVLNEKSGFLKSNGEARRALSANSIAVNKEKVTEEFTLTTKDMINNQFVLLQSGKKNYFVLNVK
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4147_CUPNH
Sequence: MTTDLKTRLTEINRQFGALGQAQPAAMSAFQGVMKAATQDGSLPAAVKELIAVALAVQKGCDDCVLFHTSQALRHRATREQLAEVLAINIEMGGGPGAMYASKALAYFDALNA
What are the official names of this protein?
Uncharacterized protein H16_B0147, ORF 7.
What is the protein family that this protein belongs to?
To H.influenzae HI_1053 and P.denitrificans COX locus Uncharacterized protein 4.
Protein: TRMB_RHIL3
Sequence: MTDMERRGRATEAFFGRRKGKALREQQAETLNSLLPAFLIDLSAAPPEPLTSLFPVPVERLRLEIGFGGGEHLIHRALETPSTGFIGVEPFVNSMQKLLSRIGETGASNIRVYNDDATQLLDWLPDGALDQIDLLYPDPWPKRKHWKRRFVSKTNLDRFHRVLKPGGLFCFASDIDTYVNWTLIKCRDHGGFEWIADNAADWLTPYEGWPSTRYEAKARREGRSSAYLTFRKV
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: RL21_COXBU
Sequence: MYAIIKTGGKQYRVTEGQMLKVEKLAQDVGQSVKFDDVLMVAAGDELHIGTPSVKDAAVTAEVVDQGRQAKIEIIKFKRRKHHMKRQGHRQDFTAVKITEIALGKAKKEVKTDGA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: KRT36_HUMAN
Sequence: MATQTCTPTFSTGSIKGLCGTAGGISRVSSIRSVGSCRVPSLAGAAGYISSARSGLSGLGSCLPGSYLSSECHTSGFVGSGGWFCEGSFNGSEKETMQFLNDRLANYLEKVRQLERENAELESRIQEWYEFQIPYICPDYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDFRTKYETELSLRQLVEADINGLRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVLRCQLGDRLNVEVDAAPPVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSSSEQLQCCQTEIIELRRTVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEAQLSEIRCDLERQNQEYQVLLDVKARLEGEIATYRHLLEGEDCKLPPQPCATACKPVIRVPSVPPVPCVPSVPCTPAPQVGTQIRTITEEIRDGKVISSREHVQSRPL
What are the official names of this protein?
Keratin, type I cuticular Ha6, Hair keratin, type I Ha6, Keratin-36, K36.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: RL3_CLOBL
Sequence: MKKAILGKKLGMTQIFNENGKVIPVTVIEAGPCTVIQKKTVEKDGYEAIQVAFGDIREKLRNKPVKGHFAKAGVSVKRHIKEFKLEDSNSLEIGQEIKADVFEAGERVDISGVSKGKGFQGTIRRWNAHRGPMSHGSKFHRAVGSMGASSDPSRTFKNKRMPGHMGNVNTTVLNLEVVRIIPEKNLILIKGGVPGPNKGLVQIRNTVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: SSRP_BACC4
Sequence: MPKGTGKVIAQNKKAFHDYFIEETYEAGLVLQGTEIKSIRAGRVNLKDAFARVHNGEVWVHNMHINTYEQGNRFNHDPLRTRKLLLHKKEIDKLAGAAKETGYALVPLRIYLKNGFAKMALGLAKGKKQYDKRHDLKEKEAKREIARAFRDRQKM
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: MUTS_DEHMC
Sequence: MENTTPLRKQYLDIKKNYPEAIVFFRLGDFYETFEEDARIAARELEIVLTSREMGKGLKVPLAGIPYHALDNYLSRLINKGYKVAICEQVTKPGETKGLVQRQVTRLVTPGTVVEPNLLQTKQNNFLLSLYLTEDSCGLAFADISTSEFGCTQTNISELEAEISRLSPAEIILPKNQSLNLPIHLKATISKLDGYYFEADIARERLLRHFECQNLSAYGCENMPLAISAAGALLNYLEETQKSSLKQLERLSVYTTADYMQMDSHTLSNLEIFRSSGGNSLKGSLLGILDQTKTAMGGRLLRKFLGQPLLKQSDIEKRLSAVDYFFEESLARTSLAKSLGQIADMERMANRIRQKTILPRELISLKNSLETVSAIHRQFGLMPPPRLAYFLNGLKPLPEMLDIINKTITDDPPSTLGDGKVIRAGFDPEMDKLCSLAGDARTFLSQMETRERERTGIKSLKLGYNRVFGYYIEISNANLGDVPPEFIRKQTLVNAERFITPELKEYENLILNAKERLLEMETGLYEQVLNQLGGFYSALLANATALAALDVLSAFAEVAVRNSYVRPVFHPENRLDIRKGRHPMVEQGLGYGSFVANDISLSAEDCQIIILTGPNMAGKSTYLKQTALIVLMAQIGSYVPAETAELCLTDRIFTRIGAREDLSAGQSTFMVEMVETASILNTATSRSLLILDEIGRGTSTYDGLAIAQAVVEYIHSQPSLTAKTLFATHYHELVELASYLPRVKNYNIAVSEDRGEVVFLHKIVPGGVDKSYGIHVAKLAGLPKWVIKRAYEVLTELENPAKKQPKSRTCQSQLQLPMTGQTSVLEEEIKELEIESLTPLAALNKLYELKKKAEEQGL
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: YEGS_XANC5
Sequence: MAPSHWRVILNGKSTDNMDLREAVGTLRKRGIQLDVRVTWEDGDAERYVGEAVADGVHTVVAAGGDGTLSEVAAALAHHEGDAASLPSLGLVPLGTANDFATAANLPIAPLEALTLIAERVAQPVDLLRIDADHGPHWCANVASGGFGTQVTVETDEGLKKMLGGLAYLITGMSRLGRIDPISARFSGPEFSWEGEFIALGLGNGRQAGGGQALCPEALIDDGLLDVTIVPDLDGEVAATLGTLVIGGKQAALERVAVRARVPWLEIVSQQPLTLNLDGEPETSRHFRIECVPARLRMHLPGECPLLGG
What is the function of this protein?
Probably phosphorylates lipids; the in vivo substrate is unknown.
What are the official names of this protein?
Probable lipid kinase YegS-like.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_SACS2
Sequence: MVKHSKGYRTRSRSLLRKSPRERGAVPSLSKLMVEYKEGDNVVVKINPSVHQGMPHRRYQGKVGKIIGKRGRAYLVSVTLGDKEKVIIVRPEHLVPFNSSG
What are the official names of this protein?
50S ribosomal protein L21e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL21 family.
Protein: 3MGH_CLOBB
Sequence: MILNREFYKRDALEVAKGLLGKILVREIDGVILRGKIVETEAYIGSIDKASHAYNGRRTERTEPLFKEGGIAYVYFIYGLYHCFNVISGESDDGQGALIRALEPLDNFDYISLKRFNKKFEELSTVKKRELTNGPSKLCMAFGIDKKDNYKVLYEKGDLYIEDSCDNHEIIETTRIGIDYAEEAIDFPWRFYIKDNKYVSKK
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: PIMT_NATTJ
Sequence: MKDKFSAQREKMVQKQLAKRDIEDPKVLDAFRKVPREEFITESKQHQAYGDHPLPIGHGQTISQPYIVAMMTQALEPSSHDIVLEVGTGSGYQTAILAELTKKVFSLERIPELSEQAGRILSKLGYQNIVLKISDDDNDLTIHEQKEFDKIIVTAAASQIPPELTQQLKEGGTLVIPVGELMFQELLVVTKHNGELRKKSLGGCRFVPLK
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SNC1_ARATH
Sequence: MMDTSKDDDMEIASSSGSRRYDVFPSFRGEDVRDSFLSHLLKELRGKAITFIDDEIERSRSIGPELLSAIKESRIAIVIFSKNYASSTWCLNELVEIHKCYTNLNQMVIPIFFHVDASEVKKQTGEFGKVFEETCKAKSEDEKQSWKQALAAVAVMAGYDLRKWPSEAAMIEELAEDVLRKTMTPSDDFGDLVGIENHIEAIKSVLCLESKEARIMVGIWGQSGIGKSTIGRALYSKLSIQFHHRAFITYKSTSGSDVSGMKLRWEKELLSEILGQKDIKIEHFGVVEQRLKQQKVLILLDDVDSLEFLKTLVGKAEWFGSGSRIIVITQDRQLLKAHEIDLIYEVEFPSEHLALTMLCRSAFGKDSPPDDFKELAFEVAKLAGNLPLGLSVLGSSLKGRTKEWWMEMMPRLRNGLNGDIMKTLRVSYDRLHQKDQDMFLYIACLFNGFEVSYVKDLLKDNVGFTMLTEKSLIRITPDGYIEMHNLLEKLGREIDRAKSKGNPGKRRFLTNFEDIHEVVTEKTGTETLLGIRLPFEEYFSTRPLLIDKESFKGMRNLQYLEIGYYGDLPQSLVYLPLKLRLLDWDDCPLKSLPSTFKAEYLVNLIMKYSKLEKLWEGTLPLGSLKEMNLRYSNNLKEIPDLSLAINLEELDLVGCKSLVTLPSSIQNATKLIYLDMSDCKKLESFPTDLNLESLEYLNLTGCPNLRNFPAIKMGCSDVDFPEGRNEIVVEDCFWNKNLPAGLDYLDCLTRCMPCEFRPEQLAFLNVRGYKHEKLWEGIQSLGSLEGMDLSESENLTEIPDLSKATKLESLILNNCKSLVTLPSTIGNLHRLVRLEMKECTGLEVLPTDVNLSSLETLDLSGCSSLRSFPLISTNIVWLYLENTAIEEIPSTIGNLHRLVRLEMKKCTGLEVLPTDVNLSSLETLDLSGCSSLRSFPLISESIKWLYLENTAIEEIPDLSKATNLKNLKLNNCKSLVTLPTTIGNLQKLVSFEMKECTGLEVLPIDVNLSSLMILDLSGCSSLRTFPLISTNIVWLYLENTAIEEIPSTIGNLHRLVKLEMKECTGLEVLPTDVNLSSLMILDLSGCSSLRTFPLISTRIECLYLQNTAIEEVPCCIEDFTRLTVLMMYCCQRLKTISPNIFRLTRLELADFTDCRGVIKALSDATVVATMEDHVSCVPLSENIEYIWDKLYRVAYLQEHFSFRNCFKLDRDARELILRSCFKPVALPGEEIPKYFTYRAYGDSLTVIVPQSSLSQNFLRFKACVVVEPLSKGKGFYPFLKVNVGFNGKQYQKSFSKDAELELCKTDHLFFCSFKFRSEDLPSKLNFNDVEFKFCCSNRIKECGVRLMYVSQEENNQQTTRSEKRMRMTSGTSEEDINLPYGLIVADTGLAALNMELSLGQGEPSSSTSLEGEALCVDYMITEEQDKGIPILFPVSGN
What is the function of this protein?
Disease resistance protein of the TIR-NB-LRR-type (PubMed:14576290).  Part of the RPP5 locus that contains a cluster of several paralogous disease resistance (R) genes (PubMed:14576290).  Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein (PubMed:14576290).  That triggers a defense system including the hypersensitive response, which restricts the pathogen growth (PubMed:14576290).  Probably acts as a NAD(+) hydrolase (NADase): in response to activation, catalyzes cleavage of NAD(+) into ADP-D-ribose (ADPR) and nicotinamide; NAD(+) cleavage triggering a defense system that promotes cell death (PubMed:31439792).  Expression regulated by MOS1 at chromatin level (PubMed:20647385).  Nuclear localization of SNC1 is essential for its activity (PubMed:22454454).  ABA deficiency can rescue high-temperature inhibition of SNC1-mediated defense responses (PubMed:22454454).
What are the official names of this protein?
Protein SUPPRESSOR OF npr1-1, CONSTITUTIVE 1, AtSNC1, Disease resistance RPP5-like protein, Probable NAD(+) hydrolase SNC1.
What is the protein family that this protein belongs to?
Belongs to the disease resistance TIR-NB-LRR family.
What are the subcellular locations of this protein?
Cytoplasm. Microsome. Nucleus. Note=Restricted to microsomes when interacting with SRFR1. Accumulates in nucleus at 22 degrees Celsius, but not at 28 degrees Celsius. Nuclear accumulation is enhanced by abscisic acid deficiency.