PharMolix/UniProtQA huggingface dataset:
Protein: PCID2_MOUSE
Sequence: MAHITINQYLQQVYEAIDTRDGASCAELVSFKHPHVANPRLQMASPEEKCQQVLEPPYDEMFAAHLRCTYAVGNHDFIEAYKCQTVIVQSFLRAFQAHKEENWALPVMYAVALDLRIFANNADQQLVKKGKSKVGDMLEKAAELLMSCFRVCASDTRAGIEDSKKWGMLFLVNQLFKIYFKINKLHLCKPLIRAIDSSNLKDDYSTAQRITYKYYVGRKAMFDSDFKQAEEYLSFAFEHCHRSSQKNKRMILIYLLPVKMLLGHMPTIELLRKYHLMQFSEVTKAVSEGNLLLLNEALAKHETFFIRCGIFLILEKLKIITYRNLFKKVYLLLKTHQLSLDAFLVALKFMHVEDVDIDEVQCILANLIYMGHIKGYISHQHQKLVVSKQNPFPPLSTVC
What is the function of this protein?
Required for B-cell survival through the regulation of the expression of cell-cycle checkpoint MAD2L1 protein during B cell differentiation (PubMed:20870947).  As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores (By similarity).  Binds and stabilizes BRCA2 and is thus involved in the control of R-loop-associated DNA damage and transcription-associated genomic instability (By similarity).  Blocks the activity of the SRCAP chromatin remodeling complex by interacting with SRCAP complex member ZNHIT1 and inhibiting its interaction with the complex (PubMed:29138493).  This prevents the deposition of histone variant H2AZ1/H2A. Z at the nucleosomes of key lymphoid fate regulator genes which suppresses their expression and restricts lymphoid lineage commitment (PubMed:29138493).
What are the official names of this protein?
PCI domain-containing protein 2, CSN12-like protein.
What is the protein family that this protein belongs to?
Belongs to the CSN12 family.
Protein: PDXT_CLOK1
Sequence: MRIGVLSFQGGVIEHIHHIESLKAIPVEIKNKYELNNIDGIILPGGESTTMGKLLMDTDMLEPLREKILKGLPTWGTCAGMILLANSIENSNKSYLKVIDIKVRRNAYGSQIDSFYYETLIPDISSSKIPLVFIRAPFITYLGSNVKSLCSIKGNVVAARYKNILVTSFHPELTDDLSFHKYFLSTCR
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: SCY1_YEAST
Sequence: MMFWSSKTGITSKYSFSSSPTFTAEPWSIYTGRPKSSSSSSPSKVSIFMFDKKQFENYLLHYGIIKSKSGSRDKVLIQEAYEILRNQANNLAKLKHPNILTLIEPLEEHSKNFMFVTEFVTSSLETVFRETDDEEQNFLQGHVKDNIVVQRGILQLVNALDFVHNRASFVHLNIQPRAIFINENSDWKISGLGYLVKIPPGTNTSEYFLPQYDPRVPPFMHLQLNYTAPEIVFENTLTFKNDYFSLGLLIYFLYTGKDLFRSENSTSEYKLEYNKFESKISTMSWDNIFSKVPQKLRHCIPKLINRDIYSRYDNITLILDSEFFQDPLVKTLNFLDDLPTKNNEEKYVFLEGLVNLLPEFPPALLQKKFLPILLELLSQFCAEKVVSDKCVGKSLDLIIKIGSTLSQLSFQEKVYPVLLSDANFPVLLKKATICLIDNLDTLKQKVKRSDFLENILKPLFNYVLHDSESDITVVCQEKLLSQIPLALEVLDFPTVKQFLLPLLSNLFTKTTSLTVKNTCVTCFQIMIEHKSIDSYTCSETVLPLFKSMKTRDPRILSKLLKLFETVPLIITDEIVLVDQVLPLMWNYSMASTLTKSQYSGYTKAINKMSSDIQKHHIAKLDDKVNDIGEDAFHKVIEPTIMKKEDPETVAAKNIEVAAMQPVKKKTGSSYGETLPQSKSILNSKPLNPKNALATRGFPTRILNSPPQTPSSRTGSKVMTKGGSNDASSTKVEEEFNEFQSFSSTGSIRQTSAPSDVWMNSTPSPTPTSASSTNLPPGFSISLQPNKRKDGSSDIPRSNVYGSLI
What are the official names of this protein?
Protein kinase-like protein SCY1.
Protein: T106C_BOVIN
Sequence: MGSRHSTYAHRPFSKRRKADDTEDSLAEREQQEAIAQFPYVEFTGRDSITCLTCQGTGYIPEQVNELVALIPHSDQRLRPQRTKQYVLLSILLCLLASGLVVFFLFPHSVLVDDDGIKVVKVTFDEQRSLVILAITATLKIRNSNFYSVAVTSLSSEVQYMNTVVGSYTTTNISLIPPRSEHLVNFTAKAEMGGPYSYVYFFCTLPYIGVHNVVVFVRTSVKISYIGHVTQSSLETHHYVDCGVNSTAV
What are the official names of this protein?
Transmembrane protein 106C.
What is the protein family that this protein belongs to?
Belongs to the TMEM106 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Membrane; Lipid-anchor.
Protein: MNMA_CROS5
Sequence: MKKVVVGLSGGVDSSVAAASLHHQGYDVIGLTLWLMKGKGQCCSEGMVDAAFICEQLGVPHHIVDTRELFEANIINYLVSGYESGVTPLPCSQCNRAVKFGPMLAYAKEELNCDRIATGHYARIRYDEQTRRYQLLRAIDRNKDQSYFLYDLSQDILKGTIFPLGEQTKEETRRIAAEFDLKTASKPESQDLCLIEAHGSMASFLDQYIKPKEGEIVDLDGKVLGTHQGIHHYTIGQRKGLGIAAPEPLYVVKLDAVMNRVIVGNRAAGGRSDCTVGRLNWVSIAEPSSPITVEVQVRYRSKAVPVSIIPIENNRVTLQFNEPQFGITPGQAAVFYDGEIVLGGGIILQDNDSVK
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPRY4_RAT
Sequence: MALPFARCWNLYRWGTKRWGVTAGESRRGISFKLEEKTAHSSLALFRGDTGVKYGLVGLEPTKVALNLERFRDWAVVLADTTVTSGRHYWEVTVKRSQQFRIGVADVDMSRDSCVGADDRSWVFSYAQRKWHSMLANEKAPIKGIGQPEKVGLLLDYEAKKLSLVDVNRISVIHTLQTDFRGPVAPAFALWDGELLTHSGLEVPKGL
What are the official names of this protein?
SPRY domain-containing protein 4.
Protein: BBS7_CAEEL
Sequence: MQNYSRTDFAQVGTTNRGCMRVIPSDKEKEHDLIVVGGQNGSLICLSRKSNDTTIIFKTQPGYPVQSLALGGPASSKKKDKIFVASQNTVRGVNRKGKTFFSMETNMAEVANRMFVRGLDVVLTGRKSYSRYHDTVDSNSYLCTEDIHDVVSLVFEEAWGSREYTSILACGNSTLQIIEGNNFAYDVRLDSVPFTVSLFMGDGGHTKLLVLYGTKTGRLGLVSVPQGGGKILWEIDTTSGACVTTIVCFNVTGGQFPDIIVGKEDGLIEIYVIDETDHAHLFGTFSCDESITGISCGHVSSKSEIDIIICTFTGWLFSLAKTSRPMIENLPVAANFSVKMQQLRSEVEELQTKVNEERLRYEEITKRQGSGTGSTFFHSFQVHENFEYSAAHGAYNLTIELVIPIDFVVVQSQLPIRLMEVEKNASVVSEVRQDALNPWPLLASYRCQANVCRLELRVQANEGDSGVINLYVCPKVMPKCAQITTHYIKALSSHMRSHDFDLYRPMNTLQFTGNFSIAEAHAWLHNLLPNVPSKCPPADTITNNYQCSVNGGTQLQVVYSKGSAVFRSDCMTTICIIRDKVSEQTMKMQIRVEVACELNQDSVNHCLKLIDPKITSMLNIEKNKLYAAALKELESNNDDVFSFLSAANAKILKDHDAIYEKSEGVSIEDSGVLAILENLMVARGKLTGRSSKGRGDAIRDLISTDYSLENMQTLFKNAMND
What is the function of this protein?
Component of the BBSome complex (By similarity).  The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia (By similarity).  The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function (By similarity).  Required for proper BBSome complex assembly and its ciliary localization (By similarity).  Required for cilia biogenesis and both the assembly and movement of intraflagellar transport proteins along the ciliary axoneme (PubMed:15231740, PubMed:17000880, PubMed:22022287, PubMed:22922713, PubMed:26150102).  Plays a role in the removal of degraded mechanosensory receptors within the cilia (PubMed:26150102).  Plays a role in guanylyl cyclase localization in the ring-like structures at the base of the finger compartment in AFD sensory neurons (PubMed:25335890).  In ciliated sensory neurons, required for the sensation of nitric oxide and avoidance of NO-producing organisms like P. aeruginosa (PubMed:30014846).
What are the official names of this protein?
Bardet-Biedl syndrome 7 protein homolog, Osmotic avoidance abnormal protein 12.
What are the subcellular locations of this protein?
Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, cilium axoneme. Note=Moves in anterograde and retrograde directions along the ciliary axonemes.
Protein: RL27_PSEFS
Sequence: MAHKKAGGSTRNGRDSEAKRLGVKMYGGQKIIPGNIIVRQRGTQFHAGYGVGMGKDHTLFAKIEGVIKFEVKGAFNRRYVSVVAA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: SCDA_STAES
Sequence: MITKEDIVADVVTDYPKSADIFRNAGIDFCCGGQESIASAVNHKPNIDLNSLLNKLNHIDNTEGNSTINPKFLNVESLIQYIQSAYHETLKEEFKNLTPYMTKLAKVHGPSHPYLLKLQDLYREFRDSMLDHIRKEDEEDFPKLIQYSQGQDVQNIKIILEDLINDHEDTGQLLNVMNQLTSDYQTPEEACGTWKLVYQRLQNIERQTHQHVHLENHVLFKKVS
What is the function of this protein?
Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions.
What are the official names of this protein?
Iron-sulfur cluster repair protein ScdA.
What is the protein family that this protein belongs to?
Belongs to the RIC family. ScdA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STAU1_MOUSE
Sequence: MYKPVDPHSRMQSTYSYGMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGKGKMRPPVKHDAPARALRTLQSEPLPERLEVNGREAEEENLNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTRVSVGEFVGEGEGKSKKISKKNAARAVLEQLRRLPPLPAVERVKPRIKKKSQPTCKTAPDYGQGMNPISRLAQIQQAKKEKEPEYMLLTERGLPRRREFVMQVKVGHHTAEGVGTNKKVAKRNAAENMLEILGFKVPQAQPAKPALKSEEKTPVKKPGDGRKVTFFEPSPGDENGTSNKDEEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHHTKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKSNISSGHVPHGPRTRPSEQLYYLSRAQGFQVEYKDFPKNNKNECVSLINCSSQPPLVSHGIGKDVESCHDMAALNILKLLSELDQQSTEMPRTGNGPVSACGRC
What is the function of this protein?
Binds double-stranded RNA (regardless of the sequence) and tubulin.  May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site.
What are the official names of this protein?
Double-stranded RNA-binding protein Staufen homolog 1.
What are the subcellular locations of this protein?
Cytoplasm. Rough endoplasmic reticulum. Note=Localizes exclusively with the rough reticulum endoplasmic (RER).
Protein: MTLD_ECO81
Sequence: MKALHFGAGNIGRGFIGKLLADAGIQLTFADVNQVVLDALNARHSYQVHVVGETEQVDTVSGVNAVSSIGDDVVDLIAQVDLVTTAVGPVVLERIAPAIAKGLVKRKEQGNESPLNIIACENMVRGTTQLKGHVMNALPEDAKAWVEEHVGFVDSAVDRIVPPSASATNDPLEVTVETFSEWIVDKTQFKGALPNIPGMELTDNLMAFVERKLFTLNTGHAITAYLGKLAGHQTIRDAILDEKIRAVVKGAMEESGAVLIKRYGFDADKHAAYIQKILGRFENPYLKDDVERVGRQPLRKLSAGDRLIKPLLGTLEYGLPHKNLIEGIAAAMHFRSEDDPQAQELAALIADKGPQAALAQISGLDANSEVVSEAVTAYKAMQ
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: RL5_VIBCH
Sequence: MAKLHDYYKSSVVAELTKQFSYTSVMQVPRIEKITLNMGVGEAINDKKLLENAASDMAIISGQKPLITKARKSVAGFKIREGYPIGCKVTLRGERMWDFLERLISIALPRVRDFRGVNGKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRGLDITITTTAGTDEEGRALLAAFNFPFRK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: QUEF_SYNSC
Sequence: MTQTPLYGERAIAEAELICFDNPRPGRPYEVSIELPEFTCKCPFSGYPDFAVLRMIYQPGPRVVELKAIKLYVNSYRDQSISHEEVTNRILDDLVAATDPVWMQLEADFNPRGNVHTVVRVSHGTRQPC
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOH_RICTY
Sequence: MIELFYEYMFPLTVIALKVVAITIPLILCVAYLTYAERRVIGLMQLRRGPNVVGPFGLLQPIADAVKLLFKEPIIPTNADKILFILAPIITFVLSLIGWAVIPFAKGVVLADINVGVLYILAISSLSVYGIIIAGWASNSKYAFLGAIRSSAQMISYEVSIGLVIVTVLLTTGTLNLSRIIEAQKTLPWWIDLMLLPMSIVFFISVLAETNRLPFDLPEAESELVAGYNVEYSSMGFALFFLGEYANMILVSAMTTTFFLGGYLPPFNLPFLDCIPGFFWFVLKVMLLLFCFLWIRATLPRYRYDQLMRLGWKVFLPLTLFGVVLVSSVLFYTDNLPSV
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NANK_SHIF8
Sequence: MTILAIDIGGTKLAAALIGADGQIRDRRELPTPASQTPEALRDALSALVSPLQAHAQRVAIASTGIIRDGSLLALNPHNLGGLLHFPLVKTLEQLTNLPTIAINDAQAAAWAEYQALEGDITDMVFITVSTGVGGGVVSGGKLLTGPGGLAGHIGHTLADPHGPVCGCGRTGCVEAIASGRGIAAAAQGELAGADARTIFTRAGQGDEQAQQLIHRSARTLARLIADIKATTDCQCVVVGGSVGLAEGYLALVEMYLAQEPAAFHVDLLAAHYRHDAGLLGAALLAQGEKL
What is the function of this protein?
Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P.
What are the official names of this protein?
N-acetylmannosamine kinase, ManNAc kinase, N-acetyl-D-mannosamine kinase.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family. NanK subfamily.
Protein: PROA_ENT38
Sequence: MLEQMGAAAKAASYKLALLSSREKNRVLEKIADYLEGQSEQILLANEQDLAEARANGLSDAMLDRLALNPARLKSIADDVRQVCNLADPVGQVIDGGLLDSGLRLERRRVPLGVVGVIYEARPNVTVDVASLCLKTGNAAILRGGKETWRTNAATVKVIQQALEECGLPAGAVQAIESPDRALVNEMLRMDKYIDMLIPRGGAGLHKLCREQSTIPVITGGIGVCHIVVDDSAEIEPALKIIVNAKTQRPSTCNTVETLLVHQDIADTFLPALSQQMAESGVTLHADPRALALLQDGPAKVEAVKSEQYDDEYLSLDLNVKVVADLDDAIAHIREHGTQHSDAILTRKLSHGNRFINEVDSSAVYVNASTRFTDGGQFGLGAEVAVSTQKLHARGPMGLEALTTYKWIGYGDDTIRA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYP3_ARATH
Sequence: MQACCGGNSMASLQQPGRVQGSVFPPIMPPVTKFSQQLKFNISKPFRSSFLKRNLVSEMRASSVSLPNVEISSKEIPFEDYGLGEVDPEVRTIITKEKDRQFRSLELIASENFTSRAVMEAVGSCLTNKYSEGLPGKRYYGGNEYIDQLETLCQNRALAAFRLDSTKWGVNVQPLSGSPANFAVYTAILSPHDRIMGLDLPHGGHLSHGFMTAKRRVSGTSIYFESMPYRLDESTGIVDYDMLEKTATLFRPKLIIAGASAYSRDFDYPRMRKIADSVGAFLMMDMAHISGLVAASVVADPFEYCDIVTTTTHKSLRGPRGGMIFFRKDPINGVDLESAVNNAVFPGLQGGPHNHTIGGLAVCLKHAQSPEFKAYQKRVVSNCRALANRLVELGFKLVSGGSDNHLVLVDLRPMGMDGARVEKILDMASITLNKNSVPGDKSALVPGGIRIGSPAMTTRGLSEKDFVVVADFIKEGVEITMEAKKAAPGSKLQDFNKFVTSPEFPLKERVKSLKERVETFTSRFPIPGV
What is the function of this protein?
Catalyzes the interconversion of serine and glycine and directs the hydroxymethyl moiety of serine into the metabolic network of H4PteGlu(n)-bound one-carbon units.
What are the official names of this protein?
Serine hydroxymethyltransferase 3, chloroplastic, AtSHM3, AtSHMT3, Glycine hydroxymethyltransferase 3, Serine methylase 3.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RB27B_MOUSE
Sequence: MTDGDYDYLIKLLALGDSGVGKTTFLYRYTDNKFNPKFITTVGIDFREKRVVYDTQGADGASGKAFKVHLQLWDTAGQERFRSLTTAFFRDAMGFLLMFDLTSQQSFLNVRNWMSQLQANAYCENPDIVLIGNKADLPDQREVNERQARELAEKYGIPYFETSAATGQNVEKSVETLLDLIMKRMEKCVEKTQVPDTVNGGNSGKLDGEKPAEKKCAC
What is the function of this protein?
Small GTPase which cycles between active GTP-bound and inactive GDP-bound states.  In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion (By similarity).  Plays a role in NTRK2/TRKB axonal anterograde transport by facilitating the association of NTRK2/TRKB with KLC1 (By similarity).  May be involved in targeting uroplakins to urothelial apical membranes (By similarity).
What are the official names of this protein?
Ras-related protein Rab-27B.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Membrane; Lipid- anchor. Late endosome.
Protein: TNAA_ECO7I
Sequence: MENFKHLPEPFRIRVIEPVKRTTRAYREEAIIKSGMNPFLLDSEDVFIDLLTDSGTGAVTQSMQAAMMRGDEAYSGSRSYYALAESVKNIFGYQYTIPTHQGRGAEQIYIPVLIKKREQEKGLDRSKMVAFSNYFFDTTQGHSQINGCTVRNVYIKEAFDTGVRYDFKGNFDLEGLERGIEEVGPNNVPYIVATITSNSAGGQPVSLANLKAMYSIAKKYDIPVVMDSARFAENAYFIKQREAEYKDWTIEQITRETYKYADMLAMSAKKDAMVPMGGLLCMKDDSFFDVYTECRTLCVVQEGFPTYGGLEGGAMERLAVGLYDGMNLDWLAYRIAQVQYLVDGLEEIGVVCQQAGGHAAFVDAGKLLPHIPADQFPAQALACELYKVAGIRAVEIGSFLLGRDPKTGKQLPCPAELLRLTIPRATYTQTHMDFIIEAFKHVKENAANIKGLTFTYEPKVLRHFTAKLKEV
What are the official names of this protein?
Tryptophanase, L-tryptophan indole-lyase, TNase.
What is the protein family that this protein belongs to?
Belongs to the beta-eliminating lyase family.
Protein: APT_BURA4
Sequence: MPHSSPGAPLDPVAFIHSQIRTVPDWPQPGVQFRDITTLLQSPKALRILVDLFVERYVDAKLDYVAGLDARGFIIAPIVAYELSVGFVPIRKVGKLPYKTRSESYDLEYGSATVEIHEDACRPGDRVIIMDDLIATGGTMMAGRNLLQRLGAVVVEGAAIIDLPDLGGSTLLRNAGLPVYTVTEFAGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YJ052_YEAST
Sequence: MHLRSRWWLALLYCKDPVSRSATTPKVETRASCLLSRAF
What are the official names of this protein?
Uncharacterized protein YJL052C-A.
Protein: STM1_SCHPO
Sequence: MSVIAPSFDMANILTELSSFLGALSLGCWVVLLIPQLLENYKNQSGESISDLFLIIWLIGDFFNVLGSIYGNVSSTVLVLSFYYIVSDSTLLMQIYYYRWKAARRIASREHEPLLQSRSLEEGLHAPIGKQQIWWDRLSTRQQFGVMGCVVIVSTIVGNLIISSASSDKSDDDLNAWPFTAGCISSVLYFCARIPQIIKNHKAKSTEGLSIIFFVLASVGNTSYAFSILVFPASDYLNYTYANLPWILGAFSTIFLDIYIFYQFIKYRNHY
What are the official names of this protein?
Seven transmembrane protein 1.
What is the protein family that this protein belongs to?
To yeast YBR147w and SpAC2E12.03c.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PDXK_ECOSE
Sequence: MSSLLLFNDKSRALQADIVAVQSQVVYGSVGNSIAVPAIKQNGLNVFAVPTVLLSNTPHYDTFYGGAIPDEWFSGYLRALQERDALRQLRAVTTGYMGTASQIKILAEWLTALRKDHPDLLIMVDPVIGDIDSGIYVKPDLPEAYRQYLLPLAQGITPNIFELEILTGKNCRDLDSAIAAAKSLLSDTLKWVVITSASGNEENQEMQVVVVSADSVNVISHSRVKTDLKGTGDLFCAQLISGLLKGKALNDAVHRAGLRVLEVMRYTQQHESDELILPPLAEA
What is the function of this protein?
B6-vitamer kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP).  Catalyzes the phosphorylation of pyridoxine (PN), pyridoxal (PL), and pyridoxamine (PM), forming their respective 5'-phosphorylated esters, i. e.  PNP, PLP and PMP.
What are the official names of this protein?
Pyridoxine/pyridoxal/pyridoxamine kinase, PN/PL/PM kinase, B6-vitamer kinase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxine kinase family. PdxK subfamily.
Protein: MOAA_SHEDO
Sequence: MHSPPALGKVNMSQLQDNFGRRFHYLRLSITDACNFKCTYCLPDGYQSQGNSPFLSLSEIELLLGAFSQMGTQKVRITGGEPSLRKDFIDIIGLAANTPNIKTVATTTNGYRLAKNAQAWYDAGLRRINVSIDSLDPKMFYQITGENRFDQVMRGVDAALESGFERVKINAVLLKGLNSQDLPRFLHWIKHMPVDLRFIELMETGLGREYFKAHHLAGTQVKQQLIRDGWQLDKADILDGPAQNFSHSDYQGRIGLIMPYEKNFCVSCNRLRVSAKGQLHLCLFTENGVNLKDLLQDKSQTPELMARLQQQLGFKTAAHSLHQGITGVTTHLASIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: DISA_MYCPA
Sequence: MTRPTLRETVARLAPGTGLRDGLERILRGRTGALIVLGNDENVEAICDGGFALDVRYAPTRLRELAKMDGAVVLSTDGSRIVRANVQLVPDPSIATDESGTRHRSAERAAIQTGYPVISVSHSMNIVTVYVGGERHVVADSATILSRANQAIATLERYKIRLDEVSRQLSRAEIEDFVTLRDVLTVVQRLELVRRIGQVIDNDVVELGTDGRQLRLQLDELLGGNDNARELIVRDYHASPEQLSEAQMTATLDELDALSDTELLDFTALAKVFGYPTTTEAQDSAVSPRGYRALAGIPRLQFAHADLLVRSFGTLQNVLAASASDLQSIDGIGAMWARHVREGLSQLAESTITDSLS
What is the function of this protein?
Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP).  c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
What are the official names of this protein?
DNA integrity scanning protein DisA, Cyclic di-AMP synthase, c-di-AMP synthase, Diadenylate cyclase.
What is the protein family that this protein belongs to?
Belongs to the DisA family.
Protein: NU4LM_MONDO
Sequence: MEQINLNMITAFTIALMGVLTYRSHLMSTLLCLEGMMLSLFILMVLLISHSHMVSMSMAPLILLVFSACEAGVGLALLVTISHTYGNDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: AROC_GRAFK
Sequence: MPGNSFGKMFKLTTFGESHGVAIGGVIDGCPAGLEIDTESVQNDLNRRRPGQSAIVTQRKEPDTVEFLSGIFEGKTTGTPIGFIIKNANQKSKDYSHIKDTYRPSHADYTYDEKYGIRDYRGGGRSSARETACRVVAGSIAKQMLKSVSFNAFVSSVGKIELNKDYSELDFSEIEKNPVRCPDPEMAREMEAYIKEIRGDGDTVGGTVQCVIKNVPIGLGEPVFDKLHAELGKAMLSINAVKGFEYGSGFEGTKMRGSEHNDHFNTDGSTQTNLSGGIQGGISNGMDIYFKVAFKPVATLMQKQQTINSKGDEVEMQGKGRHDPCVVPRAVPIVESMAALVLADYYLQNKSSKI
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: ALR_LATSS
Sequence: MTVGYLRPTRILVDQNAIYENIQNELKHLEGTDTVIFPVLKANAYGHGLIPVAEAAQAAGAAGFCVALLDEALALRRANFTEPILVLGITQPSEIELAAANQISLTVGSLEWLQEATAIAQQVPYLHPVPIHLSIDSGMGRIGMRDEAELLAAYTFIKAHSDYFDFEGVFTHFATADDPDDTYFKEQSARFNQLMTALPERPRFVHVSNSATSLWHAACNGNIIRMGISLYGLNPSGNAIPDLPYPLKQALGIESELVFVKQVAAGTKIGYGATYEASEGEWIGTIPMGYADGWLRRMQGSTVLVDGQRCEIVGRICMDQMMIRLPKRYPVGTKVVFVGKSGDDEITLQEVADYADTIHYEIICDLSDRIPRVYTGLNEH
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: ANFB_OREMO
Sequence: MRLSSMWLCSLLLILKLQLSSTYPISTGLTDTDMDILKVLLSRLEESVSEQMAVDQSAPGQRDLLDSLSTEDAGDGPQPDAGLDEAEIREFLSAKNLKSVRNDSSRRSSGCFGRRMDRIGSMSSLGCNTVGRYNPKQR
What is the function of this protein?
Cardiac hormone which may function as a paracrine antifibrotic factor in the heart.  Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion (By similarity).
What are the official names of this protein?
Brain natriuretic peptide, B-type natriuretic peptide.
What is the protein family that this protein belongs to?
Belongs to the natriuretic peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: NUSB_ECOBW
Sequence: MKPAARRRARECAVQALYSWQLSQNDIADVEYQFLAEQDVKDVDVLYFRELLAGVATNTAYLDGLMKPYLSRLLEELGQVEKAVLRIALYELSKRSDVPYKVAINEAIELAKSFGAEDSHKFVNGVLDKAAPVIRPNKK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.