PharMolix/UniProtQA huggingface dataset:
Protein: RBL_PSINU
Sequence: MSPQTETKASSGFKAGVKDYRLTYYTPDYKVSDTDILAAFRMTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYGIEPVAGEENQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFMGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFVAEALFKSQAETGEIKGHYLNATAGTCEEMMKRAVFARELGAPIVMHDYLTGGFTANTSLAFYCRDNGLLLHIHRAMHAVIDRQRNHGMHFRVLAKALRMSGGDHVHAGTVVGKLEGERDVTLGFVDLLRDDYIEKDRSRGVYFTQDWVSMPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNDIIREASKWSPELAAACEVWKEIKFVFDTIDVL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HIS2_BIFLD
Sequence: MKTFESLFAELSEKAQTRPEGSLTVDELDKGTHFIGKKIIEEAGETWMAAEYEGADRTAEEMSQLLYHVQVMMIKHGLTLEDVYKHL
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYH7_RAT
Sequence: MADREMAAFGAGAPFLRKSEKERLEAQTRPFDLKKDVFVPDDKEEFVKAKIVSREGGKVTAETENGKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKERYASWMIYTYSGLFCVTVNPYKWLPVYNAQVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKDQTPGKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKKPELLDMLLITNNPYDYAFFSQGETTVASIDDSEEHMATDSAFDVLGFTPEEKNSIYKLTGAIMHFGNMKFKQKQREEQAEPDGTEEADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVAYAIGALAKSVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLYDNHLGKSNNFQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLQKNKDPLNETVVGLYQKSSLKLLSNLFANYAGADAPVDKGKGKAKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIPEGQFIDSRKGAEKLLGSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQSRGVLSRMEFKKLLERRDSLLIIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKEMANMKEEFGRVKDALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMTERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIVKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLDQDKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTRQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILVEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSTGKSIHELEKIRKQLEAEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKNNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGAKGLNEE
What is the function of this protein?
Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction.  Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle.
What are the official names of this protein?
Myosin-7, Myosin heavy chain 7, Myosin heavy chain slow isoform, MyHC-slow, Myosin heavy chain, cardiac muscle beta isoform, MyHC-beta.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril. Cytoplasm, myofibril, sarcomere. Note=Thick filaments of the myofibrils.
Protein: YKRA_BACSU
Sequence: MDSKLIFFDIDGTIYDHDKNIPESTRKTVAELQRQGHHVFIASGRSPFLVKPILEELGIHSFISYNGQFVVFENQVIYKNPLPENAIRRLLKQADEGKHPVVFMAEDTMKATVADHPHVLEGIGSLKTDYPETDDLFYEGKEIFQLLLFCQDEEEKAYAAFPEFDLVRWHELSTDVLPHGGSKAEGIKKVIERLPFDIGDTYAFGDGLNDLQMIEYVGTGVAMGNAVPELKEIADFVTKPVDEDGIAYAVKELGLLK
What are the official names of this protein?
Putative phosphatase YkrA.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. Cof family.
Protein: DHRS9_BOVIN
Sequence: MLFWLLVLLILCGFLWNYKRQLKIANITDKYIFITGCDTGFGNLAARTFDKKGFHVIAACLTESGSTALKAETSERLHTVLLDVTDPENVKRAAQWVKNQVGEKGLWGLINNAGILGVLAPNDWLTVEDYREPVEVNLFGLISVTLNMLPLVKKARGRIINVSSIGGRLAFGGGGYSPSKYAVEGFNDSLRRDMKAFGVHVACIEPGLFKTNLSDPEKTAEKKLAIWKHLSPDIKQQYGESYIEKSLEQLKGTASFVNVDLSLVVECMDHALTSLFPKTRYAAGKDAKTFWIPLSHMPAVLQDFLLLKQKVELANPRAV
What is the function of this protein?
3-alpha-hydroxysteroid dehydrogenase that converts 3-alpha-tetrahydroprogesterone (allopregnanolone) to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone.  Also plays a role in the biosynthesis of retinoic acid from retinaldehyde.  Can utilize both NADH and NADPH.
What are the official names of this protein?
Dehydrogenase/reductase SDR family member 9, 3-alpha hydroxysteroid dehydrogenase, 3-alpha-HSD, Retinol dehydrogenase, Short-chain dehydrogenase/reductase retSDR8.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Microsome membrane. Endoplasmic reticulum membrane.
Protein: KAD_BURP0
Sequence: MRLILLGAPGAGKGTQANFIKEKFGIPQISTGDMLRAAVKAGTPLGVEAKTYMDEGKLVPDSLIIGLVKERLKEADCANGYLFDGFPRTIAQADAMKEAGVAIDYVLEIDVPFSEIIERMSGRRTHPASGRTYHVKFNPPKVEGKDDVTGEPLVQRDDDKEETVKKRLDVYEAQTKPLITYYGDWARRGAENGLKAPAYRKISGLGAVEEIRARVFDALK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_METNO
Sequence: MKRTYQPSKLVRKRRHGFRARMATVGGRRVIAARRARGRKRLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: ASPG2_ECOLI
Sequence: MEFFKKTALAALVMGFSGAALALPNITILATGGTIAGGGDSATKSNYTVGKVGVENLVNAVPQLKDIANVKGEQVVNIGSQDMNDNVWLTLAKKINTDCDKTDGFVITHGTDTMEETAYFLDLTVKCDKPVVMVGAMRPSTSMSADGPFNLYNAVVTAADKASANRGVLVVMNDTVLDGRDVTKTNTTDVATFKSVNYGPLGYIHNGKIDYQRTPARKHTSDTPFDVSKLNELPKVGIVYNYANASDLPAKALVDAGYDGIVSAGVGNGNLYKSVFDTLATAAKTGTAVVRSSRVPTGATTQDAEVDDAKYGFVASGTLNPQKARVLLQLALTQTKDPQQIQQIFNQY
What are the official names of this protein?
L-asparaginase 2, L-asparaginase II, L-ASNase II, L-asparagine amidohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the asparaginase 1 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: GLMM_STRPQ
Sequence: MGKYFGTDGVRGEANVELTPELAFQLGRFGGYVLSQHETERPKVFVARDTRISGEMLESALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASHNPALDNGIKFFGNDGFKLADDQELEIEALLDAPEDTLPRPSAEGLGTLVDYPEGLRKYEKFLVTTGTDLSGMTVALDTANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGVGSTHPEQLQELVKETGADLGLAFDGDSDRLIAVDETGEIVDGDRIMFIIGKYLSEKGLLAHNTIVTTVMSNLGFHKALDKQGINKAITAVGDRYVVEEMRSSGYNLGGEQSGHVIIMDYNTTGDGQLTAIQLAKVMKETGKSLSELAAEVTIYPQKLVNIRVENSMKERAMEVPAIANIIAKMEDEMAGNGRILVRPSGTEPLLRVMAEAPTDAEVDYYVDTIADVVRTEIGCDN
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: RLMN_STAAS
Sequence: MITAEKKKKNKFLPNFDKQSIYSLRFDEMQNWLVEQGQQKFRAKQIFEWLYQKRVDSIDEMTNLSKDLRQLLKDNFTVTTLTTVVKQESKDGTIKFLYELQDGYTIETVLMRHDYGNSVCVTTQVGCRIGCTFCASTLGGLKRNLEAGEIVSQVLTVQKALDATEERVSQIVIMGIGEPFENYDEMMDFLRIVNDDNSLNIGARHITVSTSGIIPRIYDFADEDIQINFAVSLHAAKDEVRSRLMPINRAYNVEKLIEAIQYYQEKTNRRVTFEYGLFGGVNDQLEHARELAHLIKGLNCHVNLIPVNHVPERNYVKTAKNDIFKFEKELKRLGINATIRREQGSDIDAACGQLRAKERQVETR
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  Confers resistance to some classes of antibiotics.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYW_PYRAR
Sequence: MGEDFVVTPWEVRGKVDYEKLLRQFGAKPLTAEEVALLEKYAGDVHPLIKRGFFYAHRDFDFILKWHGEGRPWALYTGRGPSGPVHIGHMVPWILLKWFSDKFGVEVYFQMTDDEKFFDDPEMKLEEATGWAYENALDVIALGFGPDKLHLIVDTKDIAPLYPIAVRVAKKLTWNTVKATFGFTDSSNIGLIFYPSLQIAVAFLPTELKKEPTPVLIPCAIDQDPYFRLARDIADSLSYPKPTTLYSKFIMALTGESKMSASNPDSAIYTMDDDKTVKHKILNAFTGGRPTAEEQRKYGGNPDICPVFHYHMLFDPDDASVEKIRQDCKSGALLCGECKLKLHEKISKFLKEHRERREKARGKVDEYRLSVKLK
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE3_ARTS2
Sequence: MHLMPREQEKLMIVVAADLARRRQARGLKLNFPESVAIISYELIEGARDGRTVADLMSYGTTLLTRDDVMEGVPEMIHDVQIEATFPDGTKLVTVHDPIR
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YK84_CAEEL
Sequence: MSPMNRQRKNKSNVLNEKDERPGCIIKEKSSVRSMAKTQPTSGRTISLSEINKPIALSKKNTEIKAAVEIQNRLTKKMAKNSERRKKMAHGPEMTAQNRTQERIDFVEFLDRHYQVMQAGVSTVKVHKMHYTKEEFENVIYEAQTIFSSEKALVDIDPPCVVVGNLHGQFNDLINMFILLGRPPETVYVFTECVTSIPKCGEEIWALFQRCFNNLPISALIATKILCMHGGLSPALTCLDELRNHPKPIRNPFRGIVNDMLWADPDPSVFEWKTSSRGSGFTFGTNVIDDVCKRLGVELIIRAHQMCFDGYWVLSGRKLITIFSAPMYCNFYKNTGCVLKVDETLGIQTVAFVPESENIEKIIEEMNRVWDISIDCIE
What are the official names of this protein?
Uncharacterized protein C30A5.4.
Protein: ATX3_CAEBR
Sequence: MSPSDDPISSIFFERQQAALCAQHALNMLLQDSLFTYENLRDLARQMDQMEHDILGNNANAVGRSENMNDSGFFSIQVIEKALETFDLKLINMENPAMAEFKANPLTARAYVLNLREHWFVLRKFGNQWFELNSVKNGPKLLTDTYVKEYLHQFAAENYSIFVVQGILPNSEADDFITLCPVVPKPTDFDKKEPNLVQKFFNSVGRRLGGSQEIPDSQEDRDLAIAMALSMESKESSESSGSDEDQLAKAIEMSLSQDPNIPSTSAAPSELTETPILGPSTSSETPSGRIPSAEQQRRDRAKFLEKLEEEKKSQNVPEE
What is the function of this protein?
Acts as chain editing deubiquitinating enzyme that binds and cleaves 'Lys-48'-linked polyubiquitin chains, with a preference for chains containing four or more ubiquitin molecules thereby modulating protein degradation by the ubiquitin-proteasome pathway.  Probably by regulating the IGF-1-insulin-like pathway, regulates lifespan.  Regulates germline DNA double-strand-break repair and apoptosis in response to DNA damage by recruiting E4 ubiquitin-protein ligase ufd-2 to DNA repair foci.  Interacts with key regulators of transcription and represses transcription.  Acts as a histone-binding protein that regulates transcription.
What are the official names of this protein?
Ataxin-3 homolog, Machado-Joseph disease-like protein.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus, nucleolus. Note=Localizes predominantly in the cytoplasm. In the germline, following ionizing radiation-induced DNA damage, localizes to foci within nucleoli where it colocalizes with cdc-48.1 and/or cdc-48.2 and ufd-2, proteasome alpha subunit and ubiquitinated proteins.
Protein: CSF11_TAKRU
Sequence: MQSFLPLLMGIMASASSVEWRHPVIWFNSKVVQSSEVVVKPGTSLELKCGGDGPVNWQTRLPKHKRYMSRSPGNLRTIRVARPTAEFTGTYKCFYSAWAQHRHLTSSVHVYVKDPNRVFWTSSTSLRVVRKEGEDYLLPCLLTDPEATDLGLRMDNGTTVPPEMNYTVYRHRGILIRSLQPSFNADYVCTAKVKGVEKTSKTFSINVIQKLRFPPYVFLEMDEYVRIVGEELQIRCMTHNPNFNYNVTWNYTTKSRVTIEERVRSSGENRLDIQSILTISAVDLADTGNISCIGTNEAGVNSSNTYLLVVEKPYIRLWPQLIPKLASQGLSVEVNEGEDLELGVMVEAYPQITDHRWHTPTSPSTSMQEHIYHARLQLKRMNAQEQGQYTFYAKSNLANGSISFHVKMYQKPIAVVRWENITTLTCTSFGYPAPQIIWYQCSGIRPTCNGNNTGLPKQNHPQALTVEVQREEYGAVEVESVFTVGLSNHRMTVECVAFNLVGVSSDTFTVEVSDKLFTSTLIGAAGVLAIFLLLLVFLLYKYKQKPRFEIRWKIIEAREGNNYTFIDPTQLPYNEKWEFPRDKLKLGKVLGAGAFGKVVEATAFGLGEDKDNTLRVAVKMLKANAHSDEREALMSELKILSHLGHHQNIVNLLGACTYGGPVLVITEYCSLGDLLNFLRQKAETFVNLVMNIPEIMENSNDYKNICNQKWYIRSDSGISSTSSSTYLEMRPSQQSHIEASGRKSLCEDNGDWPLDIDDLLRFSLQVAQGLDFLASRNCIHRDVAARNVLLTDKRVAKICDFGLARDIMNDSNYVVKGNARLPVKWMAPESIFDCVYTVQSDVWSYGILLWEIFSLGKSPYPSMAVDSRFYKMVKRGYQMSQPDFALPEIYMIMKMCWNLEPTERPTFSMISQMINRLLGGQDEQEKLIYRNVQPEQVAEGEACDEPKRYDPPCERSCDHEEEEEPLMKTNNYQFC
What is the function of this protein?
Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes.  Plays an important role in innate immunity and in inflammatory processes.  Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development.  Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration.  Activates several signaling pathways in response to ligand binding (By similarity).
What are the official names of this protein?
Macrophage colony-stimulating factor 1 receptor 1, CSF-1-R 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=The autophosphorylated receptor is ubiquitinated and internalized, leading to its degradation.
Protein: UTP25_XENTR
Sequence: MGKRRKPRREEAGSALSKKQKKHLKEFGEQHPFYDAVSKKQETTQVVQLPESSEDESRSESEAESDPEPVNMYHKLLATLNTVSDEEEEESDDEEEEALEEAEEEDEAEEVGEESEAEDEDNEDESDGEGHGQMDELPVEAEKAGDNEEEERAGDPAAEEAGEFTDAKHESKFSLETNFMDEDNEDSKDESVPCPTVATEDPFVQHVGRELEEQDISKIGTNPKKASLKWPALGQLGVSSSLPQLQPLKVEKETDLQKLYLHKPLFSTWPKVNSPFLSVDKEQNFTPLQRELFSIMNSYRDLFFPARSPTAQGEEIRHVYCLHALNHVLKANAQVLNNNSQKRDQKPGLDEEDLRDQGLTRPKVLIVVPFRESALRIVQILISLMEVGGRKVDVSNKKRFKEEFGSEPEDRPPNLKRPEDYEAVFAGNIDDHFRIGVAILQKSMRLYSPFYSSDIIIASPVGLRTIIGSEGEKKRDFDFLSSIEVLILDQADLYLMQNWEHVLHLMAHLNLQPTDSHGVDFSRVRMWNLSNWAKYYRQTLLFSSLQEPQINSIFNKHCFNYCGQVAVRNMPVTGSISHVVVQLPHVFQRLEADSLLTVIDARFEFFTSKILPQYRDAIMSHTLIYIPSYFDYVRLRNYFKKEELNFTHICEYTNRSGVSRARQFFLKGERQFLLVTERFHFYKRYTLKGIRNLIFYELPTYPHFYSEVCNMMKAWHRGEEATWTCTVLYSKYDAQRLAAVVGAERAAQMLQSKKNVHLFVTGENG
What is the function of this protein?
Component of the ribosomal small subunit processome for the biogenesis of ribosomes, functions in pre-ribosomal RNA (pre-rRNA) processing (By similarity).  Essential for embryonic development in part through the regulation of p53 pathway.  Controls the expansion growth of digestive organs and liver (By similarity).  Also involved in the sympathetic neuronal development (By similarity).  Mediates, with CAPN3, the proteasome-independent degradation of p53/TP53 (By similarity).
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 25 homolog, Digestive organ expansion factor homolog, UTP25 small subunit processor component.
What is the protein family that this protein belongs to?
Belongs to the UTP25 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: DXR1_BACHK
Sequence: MVKYISILGSTGSIGTSALDVVSAHPEHFKIVGLTANYNIELLEQQIKTFQPRIVSVATKELADTLRTRISTNTKITYGTDGLIAVATHPNSNLVLSSVVGVSGLLPTIEALKAKKDIAIANKETLVAAGHIVTELAKQNGCRLIPVDSEHSAIFQCLNGENNKEIDKLIVTASGGAFRDKTREEMKTLQAKDALKHPNWLMGAKLTIDSATLMNKGFEVMEARWLFDIPYEKIDVMIHKESIIHSLVEFIDGSVIAQLGAPDMRMPIQYAFHYPTRLPSSYEKLNLLEIGSLHFEKPDLEKFPCLQYAYECGKIGGTTPAVLNAANEIANALFLKNEIAFFDIEKTIYKTVEAHHNVKDPSLDAILEADQWARQYANQLLIKKS
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase 1, DXP reductoisomerase 1, 1-deoxyxylulose-5-phosphate reductoisomerase 1, 2-C-methyl-D-erythritol 4-phosphate synthase 1.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: MUP5_MOUSE
Sequence: MKLLLLLCLELTLVYVHAEEASSEGQNLNVEKINGKWFSILLASDKREKIEEHGTMRVFVEHIDVLENSLAFKFHTVIDEECTEIYLVADKTEKAGEYSVTYDGFNTFTILKTDYDNYIMFHLINKKDEENFQLMELFGREPDLSSDIKEKFAKLCEEHGIVRENIIDLSNANRCLQARE
What is the function of this protein?
Major urinary proteins (Mups) bind pheromones, and thus stabilize them to allow slow release into the air from urine marks.  May protect pheromones from oxidation.  May also act as pheromones themselves.  In this context, they play a role in the regulation of social behaviors, such as aggression, mating, pup-suckling, territory establishment and dominance.
What are the official names of this protein?
Major urinary protein 5.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted.
Protein: NADC_BOVIN
Sequence: MDPEGLAHLLPPATLAALADSWLREDCPGLNYVALVSGTAPSQAVLWAKSPGVLAGRPFLDAIFAQVNCQVSWFLPEGSKLVPVAKVAEVRGPAHCLLLGERVALNTLARCSGVASMAAAAVETARGTGWAGHVAGTRKTTPGFRLVEKYGLLVGGAAAHRYDLGGLVMVKDNHVMAAGGVKKAVRAARRAADFALKVEVECSSLQEAVEAAEAGADLVLLDNFRPEELHPTAATLKAQFPSVSVEASGGVRLDNLPQFCGPHIDVISLGMLTQAAPALDFSLKLFAEGATPVPHARRS
What is the function of this protein?
Involved in the catabolism of quinolinic acid (QA).
What are the official names of this protein?
Nicotinate-nucleotide pyrophosphorylase [carboxylating], Quinolinate phosphoribosyltransferase [decarboxylating], QAPRTase, QPRTase.
What is the protein family that this protein belongs to?
Belongs to the NadC/ModD family.
Protein: TBCC1_BOVIN
Sequence: MDQSRVLLWVKAEPFIVGALQIPPPSKFSLHYLRKISTYVRTRTIEGGYPRLSWSTWRHIACGKLQLAKDLAWLYFEMFDSLAMKTPEERLEWSEILSNCMSEDEVEKQRNQLSVDTLQFLLFLHIQQLNKVSLRTSLIGEEWPSPRHRAQSPDLTEKSSCHNKNWNDYSHQAFVCDHLSDLLELLLDPEQLTASFHSTHSSLVSREAVVALSFLIEGTVSGARKIYPLYELALWHPLHAETGFSKASKTFSFYKLEAWLRTCLTGNPFGTSACLKSGKKLAWAHQVEGTTKRAKIACNTHVAPRMHRMVVMSQVYKQTLAKSSDTLVGAHVKIHRCNESFIYLLSPLRSVTIEKCRNSTFVLGPVQTALHLHSCDNVKVIAVCHRLSISSTTGCIFHILTPTRPLILSGNQRVTFAPFHTHYPMLEDHMARTGLATVPNYWDNPMIVCRENSSPSVFRLLPPCEFYVFIIPFEMEGDTTEIPGGLPSAYQKALSQRKKKIQVWQKTVKEARLTKDQRKQFQVLVENKFYEWLINTGHRQQLDSLVPPAAGSKQAAG
What is the function of this protein?
Plays a role in the regulation of centrosome and Golgi apparatus positioning, with consequences on cell shape and cell migration.
What are the official names of this protein?
TBCC domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the TBCC family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes at the spindle midzone, midbody and basal bodies of primary and motile cilia.
Protein: RSMA_ALIFM
Sequence: MSTRNDVHLGHKARKRFGQNFLNDPYVIDGIVSAINPLPGQNLVEIGPGLGAITEPVGREVDKFTVIELDRDLAERLRNHPELGSKLTIHEGDAMRFDFTQLIKENNKLRIFGNLPYNISTPLMFHLFEFHKDVQDMHFMLQKEVVNRLAAGPGTKAYGRLTVMAQYFCKVMPVLEVPPTAFVPPPKVDSAVVRLVPYETLPYPATNLKWLDRVCREGFNQRRKTVRNCYKALLTKEQLEELGINPSMRPENLTLEQFVNMANWLDANHSAE
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RM37_CHICK
Sequence: MALRPVVLRRAPAHSRGILTRPGPPRPRGPLPRTPWTTRGPPPDQLARVVERRPVREQVELDTVTYAGRQYFVPGLARPRFPPWDRGWREPWHSPGPRYEDMPLRKERGCFICHQRVRMLEGVRQAQWLTKTKLVQGLPAKVLSIAENPAYQLQEQEEAVHRAVAHARLWETTEVSPRREKYCPVLFEDLIHLCRSMSVKYPSLARRMLARNYRIAATWERESTLLQIRGLNGILMNSMTPIPPVASKEEILATKDHVLETFYPISPTIDLQEVNVYQELNDTGFKDGYPYSHPHTLYFLESANKRPNRFRPEQLRAKMLMFAFGNALAKAKVLYGNDPQVLEQPIVVQSVGTDGQLFQFLVFQLNTTDLVSNDGIKNLVWIDSDQNLYESAQCVPEVKKRVVTKPTGIYGLQPETFKKFLALYLHGTV
What are the official names of this protein?
39S ribosomal protein L37, mitochondrial, L37mt, MRP-L37.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mL37 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: YIDD_COXBU
Sequence: MYKQIVHAIGKAIQTLLLGLIKSYRYLISPVLMSSCRFYPSCSCYAETALKRFGVIKGSGLTVWRLLRCHPFHPGGVDFVPEKSNEMV
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL14_AZOPC
Sequence: MIQQESRLIVTDNSGAKEVLCIRVLGGTRRRYASVGDIIVVTVKTVVPSSDIKKGIVSKAIIVRVKKEIRREDGSYIRFDDNACVLLNSTGEIRGSRIFGPVARELRTVNMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: COAX_BURL3
Sequence: MNEPHLLIDAGNSRIKWALADAQRTLVETGAFGHTRDGGADPDWSTLPRPRGAWISNVAGADVAARLDTLLDARWPGLPRTTIRSRHTQCGVTNGYTTPDQLGSDRWAGLIGAHAAFPGEHLLIATFGTATTLEALRADGRFTGGLIAPGWALMMRALGTHTAQLPTLTTDIASGLLAGAQAEPFQVDTPRSLSAGCLYAQAGLIERAWRDLADAWQAPVRLVLAGGAADDVARALTLPHTRHDALILSGLALIAAEAAAATAAQA
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.