PharMolix/UniProtQA huggingface dataset:
Protein: PTG3B_CORGT
Sequence: MASKLTTTSQHILENLGGPDNITSMTHCATRLRFQVKDQSIVDQQEIDSDPSVLGVVPQGSTGMQVVMGGSVANYYQEILKLDGMKHFADGEATESSSKKEYGGVRGKYSGIDYAFEFLSDTFRPILWALLGASLIITLLVLADTFGLQDFRAPMDEQPDTYVFLHSMWRSVFYFLPIMVGATAARKLGANEWIGAAIPAALLTPEFLALGSAGDTVTVFGLPMVLNDYSGQVFPPLIAAIGLYWVEKALKKIIPEAVQMVFVPFFSLLIMIPATAFLLGPFGIGVGNGISSLLEAVNNFSPFILSIVIPLLYPFLVPLGLHWPLNAIMIQNLNTLGYDFIQGPMGAWNFACFGLVTGVFLIALKEKNRAMRQVSLGGMLAGLLGGISEPSLYGVLLRFKKTYFRLLPGCLVGGIVMGIFDIKAYAFVFTSLLTIPAMDPWLGYTVGIAAAFFTSMLLVLFFDYRSDAERDEAKAQMAAAEQTNNTPAAPAAPVAPAAGAAAAGGAAGATAVATKPRLAAGQLVEITSPLEGHAVPLSEVPDPIFAAGKLGPGIAIEPTGNTVVAPADATVILVQKSGHAVALRLESGVELLIHIGLDTVQLGGEGFKVHVERKQQVKAGDPLITFDPEFIRSKNLPLITPVVVSNANKFGEIVGIEAAQADATTTVIKVNGAE
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  This system is involved in glucose transport.
What are the official names of this protein?
PTS system glucose-specific EIIBCA component, EII-Glc/EIII-Glc, EIIBCA-Glc.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATPF2_BRUA2
Sequence: MDATFWAFIALVIFVAIVVYMKVPGMIGRTLDERADRIKKELEEARTLREEAQQLLAEYHRKRKEAEKEAGDIVASAEREAKALLEEAKRATEEYVARRNKLAEQKIATAETDAINAVRASAVDLAVAAAGSILAEKVDAKADGNLFNDALAQVKSHLN
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b 2, ATP synthase F(0) sector subunit b 2, ATPase subunit I 2, F-type ATPase subunit b 2, F-ATPase subunit b 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: SYS_CLOP1
Sequence: MLDLKKLRSNTEEVKKALSNRGEDFDVNVIDEVIALDEERRKILVDVEALKKQRNEVSAEIPKRKKAGEDVTEVMAEMREIGGKIKADDAKVAELNDKINYIMLRIPNIPNPAVPEGETDEDNVEIKRWGEPTKFNFEPKAHWDLGTDLDLLDFERGGKVAGSRFTVYKGMGARLERSIINYFLDKHTFENGYTEVLPPYMVNRDSMTGTGQLPKFEEDAFKVENNGYFLIPTAEVPVTNMYRNETLEGDKLPIKHAAYSACFRAEAGSAGRDTRGLIRQHQFNKVELVKFCKPEQSYEELDKLVQDAESVLQGLGLPYRIVRICKGDLGFTAALKYDIEVWMPSYNRYVEISSCSNFEDFQARRANIKYKNSPKEKPQFVHTLNGSGVAIGRTVAAILENYQQEDGSVVIPEALKEYMRCDLLK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DER_AGRRK
Sequence: MSFTVAIVGRPNVGKSTLFNRLVGKKLALVDDTPGVTRDRRPGEAKLIDLRFRIVDTAGLEEADEETLEGRMRAQTELAIDEADLTLFVVDAKMGLTHVDKTLAEMLRKRGRPVVLVANKSEARGSDSGFYDAYTLGLGDPCPISAEHGQGMMDLRDAIVEAIGHDQAFPPRDDEAETNVSIPRSAVGEDGEEIDEEPAYDETRPLRVAIVGRPNAGKSTLINRFLGEDRLLTGPEAGITRDSISVDWTWRGRTVKMFDTAGMRRKARVTEKLEKLSVADTLRAIRFAETVVIIFDATIPFEKQDLQIVDLVIREGRAAVIAFNKWDMIEDRQAVLADLREKTDRLLPQARGIRAVPIAGQTGDGLDRLMQAIVDTDKVWNKRIATAKLNRWLETQQVQHPPPAVSGRRIKLKYMTQVKARPPAFMISCTRSDSLPESYVRYLINGLRADFAMPGVPIRIHFRTSENPYETKKKR
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: RBFA_ACIET
Sequence: MAAKKSSSPNRGFKVADQIQRDLTELIRDLKDPRIGMVTLQGVEVTPDYAHAKVFFSVLIGDGEASEEALNQAGGFLRNGLFKRLHIHTVPTLHFVYDRTTEKAADMNALIARAVASRSKDDDAA
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APAH_HAEIN
Sequence: MATYFVGDLQGCYDELQLLLERVDFNPTQDKLYLVGDLVARGDKSLECLRFVKSLGNAAQTVLGNHDLHLIATALDIKKVKPRDRVDAIFNAPDFDELIHWLRHQPLLVHNEKLNFLMSHAGISPDWDLKTAKSCAAEVEQILQHGDFHYLIENMYSEQPDRWSPDLQGLARHRYIINAFTRMRFCYLDHRFDFACKSPLKDAPAELTPWFNLDNPLYKQIPIVFGHWASLVDEPTPKGIYALDTGCVWNNRMTMLRWEDKQFFTQSAVKNYSDF
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: SMG_BUCA5
Sequence: MFDILIYLFENYIHNESRISIDYDSLTNDLSDIGFQRRDIYNALSWLKNLSCYKKNIIPSINPLSNKITIRIYTQEESLKLNVDCRGFILFLEQLEILTLDTREVIIERIMELDINELNLEDLKWIVLIVLFNVPGCESAYHKLENLLFNFKEDIIH
What are the official names of this protein?
Protein Smg.
What is the protein family that this protein belongs to?
Belongs to the Smg family.
Protein: TPL2A_DANRE
Sequence: MEAFSSKDMAMQAQKKILSRMASKSVAQMFIDDNSSEVLDELYRVSKEHSGNRAEAQKVVKNMIKIAVKVGVLFRHEKFSAEELSIAQEFRKKLHHGAMTAISFQEVEFTFDKSVMINLLSDCRDLLLKLVEKHLTPKSLDRIRHVFNHYSNPELLTHLYDPQGNLWSNLSKICSGLNRMIEEGKL
What is the function of this protein?
Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis.  Negative regulator of Toll-like receptor and T-cell receptor function.  Prevents hyperresponsiveness of the immune system and maintains immune homeostasis.  Inhibits jun/ap1 and NF-kappa-B activation.  Promotes Fas-induced apoptosis (By similarity).
What are the official names of this protein?
Tumor necrosis factor, alpha-induced protein 8-like protein 2 A, TIPE2 A, TNF alpha-induced protein 8-like protein 2 A, TNFAIP8-like protein 2 A.
What is the protein family that this protein belongs to?
Belongs to the TNFAIP8 family. TNFAIP8L2 subfamily.
Protein: SELA_EDWI9
Sequence: MSSDSQVLYSQIPAIDTLLRTPACAALQAQYGSQLVTQALRSLQQQARHAIQRQQALPDWCVDWGVACTRRLAETLQPAMRRVFNLTGTVLHTNLGRALLPDTAIAAAAGAMGAPVTLEYDLDDAGRGHRDRAIADRLCALTGAEDACIVNNNAAAVLLMLATLAPGRDVIVSRGELVEIGGAFRIPDVMTQAGCRLREVGTTNRTHLHDYRQAIGEHSALLMKVHTSNYAIAGFTAAVSEAELAALGQEYGLPVISDLGSGSLLDMAHYGLPAEPMPQRMLADGVDLVSFSGDKLLGGPQAGIIVGRRELIHRLQRHPLKRALRCGKMTLAALDATLQLYQQPEKLRQALPTLRHLTREASEIAACGERLLARLRPHYEEAFVLTLEPCLSQIGSGSLPVDRLPSHAITLTPRDGRGGTLTALADRWRALPCPVIGRLQEGKLWLDLRCLDDEQALLQELCQ
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DMDB_RUEPO
Sequence: MLGQMMYQPLLISSLIDHAARYHGEAQIWSVSTEGGVEETNWAGIADNARRLGSVLTDAGLAPQSRVATLAWNNRRHLEIYYGVSGAGFVLHTINPRLFPEQLVYILNHAEDRILFFDATFLPLVEGIRPHLTTVERLVLMGPRDEAAAARIEGLEFYDEFVATGDAGFDWPDLDERTASSLCYTSGTTGNPKGVLYSHRSTVLHSFGSNTRDCIGFSARDVVMPVVPMFHVNAWGTPYACAMSGSCMVLPGPDLHGEALVGLIDRYRVTIALGVPTIWQGLLATARAKGSTLESLTRTVIGGAACPPSMIAEFRDRYGVDTVHAWGMSEMSPLGTTNQPLAKHGALPIEAQHKLRENQGRPPYGVELKIVDDDGNTLPNDGQTQGDLMVRGHWVLDSYFQLQDQPILSDGWFATGDVATLDRDGYMTIRDRSKDIIKSGGEWISSVELENIAVAHPKLATAAVIGVPHPKWDERPLLVAVKAEGETPDEAELLAFFDGKIAKWQVPDRVVFVEALPLNATGKVLKRTLREQFRDVLTG
What is the function of this protein?
Involved in the assimilation of dimethylsulphoniopropionate (DMSP), an important compound in the fixation of carbon in marine phytoplankton.  Catalyzes the ATP-dependent ligation of methylmercaptopropionate (MMPA) and CoA to yield methylmercaptopropionate-CoA (MMPA-CoA) (PubMed:21562561, PubMed:24443527).  It is also active with short-chain-fatty-acid (carboxylic acids up to six carbons in length) (PubMed:21562561, PubMed:24443527).
What are the official names of this protein?
3-methylmercaptopropionyl-CoA ligase, MMPA-CoA ligase, Acyl-CoA ligase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: RL332_LACDA
Sequence: MAVKKAALACSVCGSRNYSITANSNRTKRLELNKFCKHCGKKTLHKETR
What are the official names of this protein?
50S ribosomal protein L33 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RL1_PSECP
Sequence: MAKRSKAYEAAAAKIDAEKSYAPFEAVTLAKDTNPSKFDATIEVAFRLGVDPRKADQMVRGTVNLPHGTGKTARVLVFATGDKAEAAIAAGADFVGSDDLIEKIAGGWTDFDAAVATPDLMGKVGRLGKVLGPRNLMPNPKTGTVTPDVTKAVNDIKGGKIDFRVDKHSNLHFIIGKVSFDAVKLAENYAAALEEVLRLKPSASKGRYIQKATVATTFGPGISVDPNVTKVLTEA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: NU6M_ANAPL
Sequence: MTYFVFFLGICFVVGVLGVASNPSPYYGVVGLVLASVAGCGWLLSLGVSFVALVLFMVYFGGMLVVFVYSVALAAEPFPEA
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: LEXA_AZOC5
Sequence: MLTRKQYDLLRFIHERLKETGVPPSFDEMKEALDLRSKSGIHRLITALEERGFIRRLPNRARALEVVRLPDSAAPGLAAARSGGRGFSPSVIEGSLGRVRPVVDDEEPAAVVAVPVMGRIAAGSPISAIQTRSNTLNLPPEMLGTGEHFALEVRGDSMIEAGILDGDTVLIRKCDTADTGDIIVALVDDEEATLKRLRRKGASIALEAANPAYETRIFGPDRVRIQGRLVGLIRRY
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: SAP1_ORYSJ
Sequence: MAQRDKKDQEPTELRAPEITLCANSCGFPGNPATQNLCQNCFLAATASTSSPSSLSSPVLDKQPPRPAAPLVEPQAPLPPPVEEMASALATAPAPVAKTSAVNRCSRCRKRVGLTGFRCRCGHLFCGEHRYSDRHGCSYDYKSAARDAIARDNPVVRAAKIVRF
What is the function of this protein?
May be involved in environmental stress response.
What are the official names of this protein?
Zinc finger A20 and AN1 domain-containing stress-associated protein 1, OsSAP1, Multiple stress-responsive zinc finger protein ISAP1, OsiSAP1.
Protein: PPID_HAEIN
Sequence: MLIEKMHNLTNSKISKFILGLIAVSFLVGGMSGYLFSSNDTYAAKVNGEVISQQDFLNRYNQEFEIRAQREGEAFVAQSDSPEFVTALRQNIVNLMIDQELLRQYVKELKLGVSDEMIKRAIVTDPNFQVKGKFDNAVYQRILQQNHLTSDGYASILRASLPLEQIQNGVANSEFIVPAQVKNSAEVFFQKRLARLATLSLADEMAKQSVSDDEIKTYYEANQKSFVQPEQVKVQYIDLSADNISRNLQVTDVEIAQYYQDNKAQFMTQHLAHIQFANEQDAKVAYEELQKGANFADVAKAKSLDKISGENGGDLGWVNENELPKAFEDAAAALQVGQYSQPINVDGNYHIVLVQERKAQSLENVKAQIADLVRKSLMESRYFSLEKQASDKAFEDSKSLNTAAQAAGVKVQESDYFSRQNVPAGLNFPNVIYTIFESDTTNVGMNSEPINVGDYHTIIVRVLDRKAEGVKSLEEAKIDIETFLKRQKAENALNGKAQQAVKKLSENPESKVDGINFSSEQTFTLSENKDPILTNGIFSIAKPESSKALYQVVHNSNGDVVVVALNKVEQGSLSEKELSQFAMQLLRSHQSELQVQLIQGLRERAKIEVNDSFINQDDEAQQ
What is the function of this protein?
Chaperone that functions as a gatekeeper on the periplasmic side of the SecYEG translocon.  Facilitates the translocation of precursor proteins across SecYEG by interacting with the translocating substrate.  Also plays a role in the release of newly synthesized secreted proteins at the periplasmic exit site of the Sec translocon.
What are the official names of this protein?
Periplasmic chaperone PpiD, Periplasmic folding chaperone.
What is the protein family that this protein belongs to?
Belongs to the PpiD chaperone family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side. Note=Located at the lateral gate of SecY.
Protein: RL19_BAUCH
Sequence: MFNLIQHIEHEQMKNLPAFRPGDSVEVKVWVVEGSKKRLQSFEGMIIAIRNRGLHSAFTVRKISNGEGVERVFQMHSPIIESITVKRCGFVRKAKLYYLRKRTGKAARIKERISS
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: EI3G1_DROPS
Sequence: MPGVETIKSSWADEVELDYGGLPPTTENVENGHKYVTEYKYNKDDKKTKVVRTYKISKQVVPKTVAKRRTWTKFGESKSDKPGPNSHTTMVSEEIIMQFLNSKEDEKANDPLLDPTKNIAKCRICNGEHWSVNCPYKGTAMDTNLMEKKAAAAASAAVDAPKSGKYVPPFLKDSQKGGLGMRGRDDTAAIRISNLSESMTEADLEELVKKIGPQSKMYLARDKNTGLCKGFAYVHFKQRKDAAAAIEILNGHGYDHLILSVEWSKPQNN
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.  This subunit can bind 18S rRNA.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit G-1, Eukaryotic translation initiation factor 3 RNA-binding subunit 1, eIF-3 RNA-binding subunit 1, Eukaryotic translation initiation factor 3 subunit 4-1.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit G family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WNT16_HUMAN
Sequence: MDRAALLGLARLCALWAALLVLFPYGAQGNWMWLGIASFGVPEKLGCANLPLNSRQKELCKRKPYLLPSIREGARLGIQECGSQFRHERWNCMITAAATTAPMGASPLFGYELSSGTKETAFIYAVMAAGLVHSVTRSCSAGNMTECSCDTTLQNGGSASEGWHWGGCSDDVQYGMWFSRKFLDFPIGNTTGKENKVLLAMNLHNNEAGRQAVAKLMSVDCRCHGVSGSCAVKTCWKTMSSFEKIGHLLKDKYENSIQISDKTKRKMRRREKDQRKIPIHKDDLLYVNKSPNYCVEDKKLGIPGTQGRECNRTSEGADGCNLLCCGRGYNTHVVRHVERCECKFIWCCYVRCRRCESMTDVHTCK
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Probable developmental protein.  May be a signaling molecule which affects the development of discrete regions of tissues.  Is likely to signal over only few cell diameters (By similarity).
What are the official names of this protein?
Protein Wnt-16.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: RPOZ_HELPY
Sequence: MKKERTESLVAQALKNIGNDRYMLDNLVFARVKQLNAGAKTLVNMDPKRHKLVDIAIREIAEGKIDIDRIDERN
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: FDHD_SALEP
Sequence: MNNILSEEVLNVTDFTTSRQLTLWKREDLQSPQLDDVAEEVPVALVYNGISHVVMMASPKDLTHFAMGFSLSEGIIDSPREIYGMDVVPSCNGLEVQIDLSSRRFMGLKARRRALAGRTGCGVCGVEQLNDIGKPVQPLPFSQTFNLGNLDRALKHLNDFQPTGKLTGCTHAAAWVMPSGELAGGHEDVGRHVALDKLLGRRATEGEEWRQGAALVSSRASYEMVQKSAMCGVEILFAVSAATTLAVDVAERCNLTLVGFCKPGRATIYTHPQRLIAD
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity.  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
What are the official names of this protein?
Sulfur carrier protein FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREG_FRASN
Sequence: MHLEHDRPLGGGGAPAASGGAGPRWQSPPGTPAGPAPTDRALRVGVGGPVGSGKTALVAALCRALAGRIRLGVVTNDIYTTEDADFLRSAGVLDPGRIRAVETGCCPHTAIRDDITANLDAVEDLESDLGRLDLILVESGGDNLTATFSYGLVDRQIFVIDVAGGDKVPRKGGPGVAGSDLLVVNKTDLAPLVGADLAVMARDAAAMRGGRADRPVLFTSLRSDAGASDVADWVLAQLPSPARPQ
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRE22_PARTE
Sequence: MNLKITINQQASISEKLIIANLEQLLIFRDNTFNKIDCDQQITLKDAVQISQILNDQGVLNYEGEINEQITTYLEACGLYSQGQGQFIKRTLQTKKINIPQQDFNNCYGKYDYIEQKFQNQINFFKQVDLKGNQETIDENELLNDGVEVKQVESCASKPRACANCTCGRKEMEEKQDKEQLLEQLKNNSVKGCGSCYLGDAFRCANCPFRGLPAFKDGEQVKVLQDDVFLKEKEETDQIKLENGKVKLMI
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.  Required for the maturation of extramitochondrial Fe-S proteins.  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex.  Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase.  Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit.
What are the official names of this protein?
Anamorsin homolog 2, Fe-S cluster assembly protein DRE2 homolog 2.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space.
Protein: PSP_THET2
Sequence: MKLLLLDLDDTLLQDLPVSRAVLEDLGRKAGVEGFFARVKARAEALFREAPFYPWAEAIGHSALEALWARYSTPGLEALAAWAGPFRERVFREALEEAGGAPERARELAEAFFRERRRYPLYPEAEAFLAEARRRGLALALLTNGVPDLQREKLVGAGLAHHFSLVLISGEVGIGKPDPRLFRMALCAFGVAPEEAAMVGDNPQKDVRGARLAGVRAVWVDRGLRPEDPEASPDLRVGDLREVFLAEAL
What is the function of this protein?
Catalyzes the last step of the phosphorylated serine biosynthetic pathway, i. e.  dephosphorylation of O-phospho-L-serine to form L-serine.  Is also able to dephosphorylate O-phospho-D-serine with similar efficiency.  Displays a poor activity on L-phosphothreonine, and cannot use L-phosphotyrosine, pyridoxal phosphate, glucose 6-phosphate, or fructose 6-phosphate as substrates.
What are the official names of this protein?
Phosphoserine phosphatase, PSP.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily.
Protein: ACCD_FLAPJ
Sequence: MSWFKRKEKGITTATEDKMDVPKGLWYKSPTGKIIDAEELARNLWVSPEDDFHVRIGSAEYFHILFDNNEFTELDANMTSKDPLGFVDTKKYADRLVDVMQKTKLKDAVRTAVGKSKGRDLVICCMDFAFIGGSMGAVVGEKIARGIDHSIKNKIPFVMISKSGGARMMEAAYSLMQLAKTSAKLAQLAEAKIPYISLCTDPTTGGTTASYAMLGDINISEPGALIGFAGPRVVRDTTGKDLPEGFQTAEFVLEHGFLDFITPRKELKDKINLYLDLILNNEVR
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS4_LISMH
Sequence: MQIFPAIDLKNGQCVRLFQGDFSKKTVVNEDPIAQAKGFATDGATYLHIVDLDGALEGRPINLEVIQKMKTTAKIPVQVGGGIRSMAQVDYYLESGIDRVIIGSAALTDPDFLRAAVQKYGAKIAAGIDAKNGLVATRGWLDVSQVNYLDLAKRMEKVGVETIIYTDISRDGTLTGPNLEQMANLKEHVKVNLIASGGVSSRADLEALAKLGLYGAIAGKALYNRQISMSDIVEVEQIAY
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31B_YERPS
Sequence: MKPNIHPPYRTVVFHDTSADAYFTVGSTIATERTIERDGQTYPYVTLDISSASHPYYTGKQKEFAKEGSTARFHQRFGSFLTKKTN
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: P4K2B_RAT
Sequence: MPEPPRDIMAEACEATRPSEDEDEEREPLLPRVAWAQPRRGAPGSAVRLQADQGAAVLREPATEEPPVVSEDRSISASLSTELDRTRNAVSETNTFLEDPEFADVVLKAEQAIEIGVFPERISQGSSGSYFVKDSKRTIIGVFKPKSEEPYGQLNPKWTKYVHKVCCPCCFGRGCLLPNQGYLSEAGAYLVDTKLQLGIVPKTKVVWLVSETFNYSAIDRAKSRGKKYALEKVPKVGRKFHRIGLPPKIGSFQLFVKDYKEAEYWLRRFEAEPLPENIRKQFQSQFERLVILDYIIRNTDRGNDNWLVKYDEMKYAKKIESEESNWIDDKQLLIRIAAIDNGLAFPFKHPDEWRAYPFHWAWLPQAKVPFSEETRNLILPFISDMNFVQDLCEDLYELFKTDKGFDRAAFESQMSVMRGQILNLTQALRDGKSPMQLAQMPCVIVECSKSGGQGRVVHLGSSFTQTVHCRKPFFSSW
What is the function of this protein?
Together with PI4K2A and the type III PI4Ks (PIK4CA and PIK4CB) it contributes to the overall PI4-kinase activity of the cell.  This contribution may be especially significant in plasma membrane, endosomal and Golgi compartments.  The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3).  Contributes to the production of InsP3 in stimulated cells and is likely to be involved in the regulation of vesicular trafficking.
What are the official names of this protein?
Phosphatidylinositol 4-kinase type 2-beta, Phosphatidylinositol 4-kinase type II-beta.
What is the protein family that this protein belongs to?
Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Golgi apparatus membrane; Peripheral membrane protein. Endoplasmic reticulum membrane. Cell membrane. Early endosome membrane. Note=Mainly cytosolic, association with membranes of the Golgi, endoplasmic and plasma membrane is stimulated by active RAC1. Association with early endosomes has not been confirmed.