PharMolix/UniProtQA huggingface dataset:
Protein: RHLB_HAEIG
Sequence: MQQDYLSQQRFSALPLHPIVRGALAKKGFDFCTPIQALSLPISLNGRDVAGQAQTGTGKTMAFLTATFHHLLTHQDPNLEYPHPRALILAPTRELAVQISNDAEFLAKASGLKTALAYGGDGYDKQLQVIECGVDILIGTTGRVIDYVKQGVIGLDEIQVVVLDEADRMFDLGFIRDIRYLLRKCPAPQARLTMLFSATLSYKVRELAFEDMNDPEYIEIEPEQKTGHRIKEELFYPSNQDKMALLLTLMEDEWPERCIVFANTKHRCEEIWGYLAADGHRVGLLTGDVAQKKRLSLLKQFTDGDLDILVATDVAARGLHISDVTHVFNYDLPDDREDYVHRIGRTGRAGESGVSISFACEEYAMNLPAIEEYIGHSIPVSQYETEALLELPKPYRLKRAVPPQGHTRHRSYHTK
What is the function of this protein?
DEAD-box RNA helicase involved in RNA degradation.  Has RNA-dependent ATPase activity and unwinds double-stranded RNA.
What are the official names of this protein?
ATP-dependent RNA helicase RhlB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. RhlB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THYX_BORBU
Sequence: MNKEYKILDNGFLKLIDFMGDDRRIVKAARISYREESVKRKDAELIDYLIRNGHTSPLEQVVFTFHVKAPIFVARQWMRHRTARINEVSGCYSLAREEFYVPLEEDLKCQTSSNSSEKEFKSLEKLSDKIKHHQKHSYELYQDMINANIPKELSRIVLPLSLYTEWYWQIDLNNLFHFIKLRLALDSPKEIKENSPKEMREYAKALISIVREIVPIAFNSFENHFLRGKRFSHEEIIAIINALDLNKLSMDAEKLNLLKDKLGID
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
What are the official names of this protein?
Flavin-dependent thymidylate synthase, FDTS, FAD-dependent thymidylate synthase, Thymidylate synthase ThyX, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase ThyX family.
Protein: ANFC_BOVIN
Sequence: MHLSQLLACALLLALLSLRPSEAKPGAPPKVPRTPSGEEVAEPQAAGGGQKKGDKTPGGGGANLKDDRSRLLRDLRVDTKSRAAWTRLLHEHPNARKYKGGNKKGLSKGCFGLKLDRIGSMSGLGC
What is the function of this protein?
Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation (By similarity).  May also be vasoactive and natriuretic.  Acts by specifically binding and stimulating NPR2 to produce cGMP.  Binds the clearance receptor NPR3 (By similarity).
What are the official names of this protein?
C-type natriuretic peptide, SVSP15.
What is the protein family that this protein belongs to?
Belongs to the natriuretic peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: INS2_HUSDA
Sequence: AANQHLCGAHLVEALYLVCGERGFFYTPNKVGIVEQCCHSPCSLYDLENYCN
What is the function of this protein?
Insulin decreases blood glucose concentration.  It increases cell permeability to monosaccharides, amino acids and fatty acids.  It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver (By similarity).
What are the official names of this protein?
Insulin-2.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GLK_STRMK
Sequence: MSANSQPVLVADIGGTNARFALADTSLDAPLLKESIREYAVAEFPSLGDAARHHLEQIGAAASRGVFAVAGRVDGDEARITNHPWVISRSRTAAMLGFDELHLINDFAAQAMAISLLQPEDVVQVGGAAWVPGKPGQPRNYAVIGPGTGLGVGGLILRHGRCYPLETEGGHVSFPPGTPEEIRILEILSEQFGRVSNERLICGPGLVNIHRAVCEMAGIDPGQLQPVDVTARALHGDPQAMRTVDVFCAVFGAIAGDLVLTQGAWDGVFLTGGLTPKMLDSLQHSGFRQRFEHKGRFSSIMARVPSLAVMHPHAGLLGAAAYAADAERDAPGVAA
What are the official names of this protein?
Glucokinase, Glucose kinase.
What is the protein family that this protein belongs to?
Belongs to the bacterial glucokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUCC_BACC2
Sequence: MNIHEYQGKAVLRSYGVSVPNGKVAFTVEEAVEAAKELGTDVCVVKAQIHAGGRGKAGGVKVAKNLDEVRTYAESILGTTLVTHQTGPEGKEVKRLLIEEGCDIKKEYYVGLVLDRATSQVVLMASEEGGTEIEEVAEKTPEKIFKEYIDPAVGLQGFQARRIAFNIHIPKELVGQAVKFMMGLYRAFIEKDCSIAEINPLVTTGEGKVMALDAKLNFDSNALYRHKDILELRDLDEEDSKEIEASKYDLNYIPLDGNIGCMVNGAGLAMATMDIIKHYHGDPANFLDVGGGATAEKVTEAFKIILSDKNVKGIFVNIFGGIMKCDVIAEGVIEATKQVGLELPLVVRLEGTNVELGKKILNESGLNIVAAESMADGAQKIVSLVG
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: IOVO_GRUJA
Sequence: TATVDCSDYPKPACTLEYMPFCGSDSKTYSNKCNFCNAVVDSNGTLTLSHFGKC
What are the official names of this protein?
Ovomucoid.
What are the subcellular locations of this protein?
Secreted.
Protein: RNLB_ECOLI
Sequence: MFEITGINVSGALKAVVMATGFENPLSSVNEIETKLSALLGSETTGEILFDLLCANGPEWNRFVTLEMKYGRIMLDTAKIIDEQDVPTHILSKLTFTLRNHPEYLEASVLSPDDVRQVLSMDF
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system.  A labile antitoxin (half-life of 2. 1 minutes) that inhibits the endonuclease activity of cognate toxin RnlA but not that of non-cognate toxin LsoA.
What are the official names of this protein?
Antitoxin RnlB.
Protein: COWN_RHOPB
Sequence: MNVPFDRYVSFKNADWEGKSQRVMAKLQSHIDAADNPFWGYFAKKRTELNEKQGLDDLRVLHNYLPTLREILEESGDDETLAMLEDLEVTCM
What is the function of this protein?
Is required to sustain N(2)-dependent growth in the presence of low levels of carbon monoxide (CO).  Probably acts by protecting the N(2) fixation ability of the nitrogenase complex, which is inactivated in the presence of CO.
What are the official names of this protein?
N(2)-fixation sustaining protein CowN, CO weal-nitrogenase.
What is the protein family that this protein belongs to?
Belongs to the CowN family.
Protein: Y1132_THERP
Sequence: MAGHSKWAQIKRQKQAADFRKGQIFSKLAREIHVAVREGGPNPETNVRLRMAIERARREGMPKDTIENAIAKASGAAGGAAEYETIVYEGYGPGGVAIMAIALTDNRNRTASVVRHIFSKYGGSLGETGSVAWQFETVGQIVVATDGHDPEEIALAAIDAGARDFEVEDDSVIITTDPDQLSDVAEKLEAAGYQIRQADIQRIPTTTVELEGGQAQSALKLLEALEDLDDVQEVYTNASFPAEVRSAV
What are the official names of this protein?
Probable transcriptional regulatory protein trd_1132.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_PARZE
Sequence: MAEDIEIDLDDLERRMKGAMDSLRAEFASLRTGRASASMVEPVQVEAYGQMTPINQVGTVNVPEPRMVTINVWDKGMVGKVEKAIRESGLGINPQTNGTIIMLPIPELNEERRRELTKVAAQYAEHARVAIRNVRRDGMDQIKKGKANGMPEDDQKFWETAVQELTDKSIGNVDQALEAKQAEIMQV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RGS11_MOUSE
Sequence: MERVVVSMQDPDQGVKMRSQRLLITVIPHAVAGRDLVEWLVQKFCILEDEALHLGTLLAQHGYIYPLRESRDLTLRPDETPYRFQTPYFWTSTMWPAAELDYAIYLAKKNIQKQGALVDYEKEHYALLHKKINHAWDLVLMQAREQLRAAKQRRKGDRMVISCQEQTYWLVNKPPPGAPNILEQGPERGSYNPSHMQMSSDFYKCEIECFRKALGRNRVKSSACLEAYLKFSSQHGPHDPIMSGCLPSNPWITDDVTYWAMNAPNVAAPTKLRVERWSFSFRELLDDPVGRAHFMDFLQKEFSAENLSFWEACEELRFGGQAQVPTLVDSVYQQFLAPGAARWINIDSRTMERTLEGLRQPHRYVLDAAQLHIYMLMKKDSYPRFLKSDIYKGLLEEAVIPLETKRWPFPFLRKPLHSSPSPALQSTPREPAATSSPEGADGE
What is the function of this protein?
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.
What are the official names of this protein?
Regulator of G-protein signaling 11.
Protein: PINO_DROME
Sequence: MKTGSNNNHISASSSSSNNNNNSSLVQQQQQRSTTSVSVSSSHIVTEWEDGIIFDVDDPDFCNLATDKLNFIVPSAANMSIASVHGPQIADICSPLSHHNLGLSASLPDLVGSPLEISMDNVLTIEELRQHMGSCFTCGVSWTDDHVSLDCSECGGYSLERPCPLCDGQCGVQWKRDFAMSHACSQARWVGVCISYPEVVAGVQLPVGAGAGAATSCAAAAANQLRLAQELCSRLEQLSTSTASKSGRI
What is the function of this protein?
Plays a role in olfaction.
What are the official names of this protein?
Protein pinocchio.
What is the protein family that this protein belongs to?
Belongs to the pinocchio family.
Protein: WHIA_TROWT
Sequence: MNSLLQALHLLRCDLLSLPIGDAQTRSAELTALLRFGADLNIIKRRVVIEVKLCGSLLLNRVESVLRNIYGITPKLIRSTPRNDIGESCFLLRIDDPSLARKLGLIDTSLAPVRGLPNHLALASGSALKGLVRGAILASGVFTESTRKFAMEVYAPSNETALCLQGSINKLNVIAKIKEVRGSYKVVIRDIDNVAPLLRNVGARNSVEKIEQFIKLRHPENLGPRLPNFDDANLRRSAIAAASSVRRIERALQILKGDAPQHLLYAGQLRLNNTHASLEELGKLAEPAMTKDAIAGRIRRLLCLADKRAKTLGIPDTFS
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: PSD11_XENTR
Sequence: MAAAAVIEFQRAQEMLVSDRAASIDILQSIVKRDIQESDEEALRVKEQSILELGGLLAKTGQAAELGGLLKYVRPFLNSISKAKAARLVRSLLDLFLDMEAATGQEVELCLECIEWAKAEKRTFLRQALEARLVSLYFDTKRYQEALQLGSQLLRELKKMDDKALLVEVQLLESKTYHALSNLPKARAALTSARTTANAIYCPPKLQAALDMQSGIIHAAEEKDWKTAYSYFYEAFEGNDSIDSPKAITALKYMLLCKIMLNTPEDVQALVSGKLALRYAGRQTEALKCVAQASKNRSLANFEKALTDYKAELRDDPIISTHLAKLYDNLLEQNLIRVIEPFSRVQIDHISSLIKLPKPEVERKLSQMILDKKFHGILDQGEGVLIIFDEPPVDKTYEAALETIQNMSKVVDSLYNKAKKLT
What is the function of this protein?
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.  This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required.  Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.  In the complex, PSMD11 is required for proteasome assembly.  Plays a key role in increased proteasome activity in embryonic stem cells (ESCs): its high expression in ESCs promotes enhanced assembly of the 26S proteasome, followed by higher proteasome activity.
What are the official names of this protein?
26S proteasome non-ATPase regulatory subunit 11, 26S proteasome regulatory subunit RPN6.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S9 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol.
Protein: SECB_SALA4
Sequence: MSEQNNTEMAFQIQRIYTKDVSFEAPNAPHVFQKDWQPEVKLDLDTASSQLADDVYEVVLRVTVTASLGEETAFLCEVQQAGIFSISGIEGTQMAHCLGAYCPNILFPYARECITSLVSRGTFPQLNLAPVNFDALFMNYLQQQAGEGTEEHQDA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TLR4_BOSTR
Sequence: MMARVRLAAALIPATAILSCLRTESWDPCVQVVPNISYQCMELNLYKIPDNIPISTKMLDLSFNYLRHLGSHNFSSFPELQVLDLSRCEIKIIEDDTFQGLNHLSTLILTGNPIQSLAWGAFSGLSSLQKLVAVETNLVSLNDFPIGHLKTLKELNVAHNFIHSFKLPEYFSNLPNLEHLDLSNNKIQNIYYEDVKVLHQMPLLNLSLDLSLNPLDFIEPGTFKEIKLNGLTLRSNFNSSHVMKTCIQGLAGLKINRLVLGEFKNERKLKGFDRSILEGLCNLTIEQFRIAYLDEFSGDDTDLFNCLENVSVISLLSVSLGSLQALLKDFRWQHLEIINCDFDKFPALKLSSLKKFVFTDNKDISSFTEFQLPSLQYLDLRRNHLSFKGCCSHADFGTTNLKHLDLSFNDVITLGSNFMGLEKLEHLDFQHSTLKQINAFSVFLSLRNLRYLDISYTNVRIVFHGIFTGLVSLKTLKMAGNTFQDNLLPDIFTELTNLTVLDLSKCQLEQVAQTAFHSLSSLQVLNMSHNKLLSLDTFLYEPLHLLRILDCSFNRIMDSKEQDLQNLPRNLTWLNLTQNAFACVCEHQRFLQWVKDQRQLLVGAEQMMCAEPLDMKDMPVLSFRNATCQMSKMIISVSVVTVLLVSVVGVLVYKFYFHLMLLAGCKKYGRGESTYGAFVIYSSQDEDWVRNELVKNLEEGVPPFQLCLHYRDFIPGVAIAANIIQEGFHKSRKVIVVVSQHFIQSRWCIFEYEIAQTWQFLSSRAGIIFIVLQKLEKSLLRQQVELYRLLSRNTYLEWEDSVLGRHVFWRRLRKALLAGKPQSPEGTADAETNPQEATTST
What is the function of this protein?
Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS).  Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).  Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate.  In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42.  In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to CD36.  This event induces the formation of a heterodimer of TLR4 and TLR6, which is rapidly internalized and triggers inflammatory response, leading to the NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion.  Binds electronegative LDL (LDL(-)) and mediates the cytokine release induced by LDL(-) (By similarity).  Activated by the signaling pathway regulator NMI which acts as damage-associated molecular patterns (DAMPs) in response to cell injury or pathogen invasion, therefore promoting nuclear factor NF-kappa-B activation (By similarity).
What are the official names of this protein?
Toll-like receptor 4.
What is the protein family that this protein belongs to?
Belongs to the Toll-like receptor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Early endosome. Cell projection, ruffle. Note=Upon complex formation with CD36 and TLR6, internalized through dynamin-dependent endocytosis. Colocalizes with RFTN1 at cell membrane and then together with RFTN1 moves to endosomes, upon lipopolysaccharide stimulation.
Protein: MDH_AERS4
Sequence: MKVAVLGAAGGIGQALALLLKNRLPAGSELSLYDIAPVTPGVAVDLSHIPTDVKVKGFCGEDPSPALVGADVVLISAGVARKPGMDRSDLFNINPGIVKNLVEKCAASCPKALIGIITNPVNTTVAIAAEVLKKAGVYDKRRLFGVTTLDVIRAETFVADAKGLNVDKVRVNVIGGHSGVTILPLLSQIEGASFSAEEVAAMTKRIQNAGTEVVEAKAGGGSATLSMGQAACRFGLSLIKGLQGEANVIECAYVEGDGKHATFFAQPILLGKNGVETVLDYGKLSAFEQEAMEGMLATLKADIQLGVEFVK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: ACPS_CLONN
Sequence: MIIGIGTDIVEIDRINKSIERTPNFINKLFTKKEIEYFISRKMRPEFIAGKFAAKESVAKALGTGFRKFGFRDIEIDKDELGKPLVHLSGGAKETANKFGDYKLHLSISHGRENAIAYAILEVDNNGNCNSSKDEGHR
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHO_APLCA
Sequence: MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVRHFCPNVPIILVGNKKDLRNDESTKRELMKMKQEPVRPEDGRAMAEKINAYSYLECSAKTKEGVRDVFETATRAALQVKKKKKGGCVVL
What are the official names of this protein?
Ras-like GTP-binding protein RHO.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: BH020_ARATH
Sequence: MDDSSFMDLMIDTDEYLIDDWESDFPICGETNTNPGSESGSGTGFELLAERPTKQMKTNNNMNSTSSSPSSSSSSGSRTSQVISFGSPDTKTNPVETSLNFSNQVSMDQKVGSKRKDCVNNGGRREPHLLKEHVLAERKRRQKLNERLIALSALLPGLKKTDKATVLEDAIKHLKQLQERVKKLEEERVVTKKMDQSIILVKRSQVYLDDDSSSYSSTCSAASPLSSSSDEVSIFKQTMPMIEARVSDRDLLIRVHCEKNKGCMIKILSSLEKFRLEVVNSFTLPFGNSTLVITILTKMDNKFSRPVEEVVKNIRVALAE
What is the function of this protein?
Transcription activator that regulates the expression of at least NAI2, PYK10 and PBP1.  Required for and mediates the formation of endoplasmic reticulum bodies (ER bodies).  Involved in the symbiotic interactions with the endophytes of the Sebacinaceae fungus family, such as Piriformospora indica and Sebacina.
What are the official names of this protein?
Transcription factor NAI1, Basic helix-loop-helix protein 20, AtbHLH20, bHLH 20, Transcription factor EN 27, bHLH transcription factor bHLH020.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y022_RICCN
Sequence: MDKCRKANLYQKMGYYNEYILCKFEESLKYYKKALKIDQELVHPSFIASSLNNIGVIYEN
What are the official names of this protein?
Uncharacterized protein RC0022.
Protein: DAPA_CITBB
Sequence: MFQGSIVAIVTPFKNGAVDEEKLRELVEFQIENGTDAIVPCGTTGESSTLSYVEHDRVIQVVVEQVNKRVPVIAGTGSNSTHEAIEITQHAKELGADGALLVTPYYNKPSQEGLFRHYKAVADAVALPQILYNVPGRTGVNLLPETVARLSVHQNIVAIKEATGSLQQASEVLALCGDKIDVLSGDDFITLPIMAAGGKGVISVTANIMPKEVSSLVDAFNAGNMEEARRLHLYLLKISNAMFIESNPVPVKAAVSLMGKCSSEVRLPLAPLMEANLAKLTAIMKEYKLI
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYNRG_MOUSE
Sequence: MALRPGAGASGAAGAGAGPGGAGSFMFPVAGGMRPPQAGLIPMQQQGFPMVSVMQPNMQGMMGMNYSSQMSQGPIAMQAGIPMGPMPAAGVPFLGQPPFLSMRPAGPQYTPDMQKQFAEEQQKRFEQQQKLLEEERKRRQFEEQKQKLRLLSSVKPKTGEKNRDDALEAIKGNLDGFSRDAKMHPTPASHPKKQGPSLEEKLLVSCDVSASGQEHIKLNTPDAGHKAIVPGSSKNCPGLMAHNRGAVDGCVSGPASAEAEKTSDQTLSKEESGVGVFPSQDPAQSRMPPWIYNESLVPDAYKKILETTMTPTGIDTAKLYPILMSSGLPRETLGQIWALANRTTPGRLTKEELYTVLAMVAVTQRGVPAMSPDALSQFPAAPIPTLSGFPMTLPTPVSQPTAMPSGPTGSMPLTLGQPIMGINLVGPVGGAAAPTSSGFMPAYPSNQVGKTEEDDFQDFQDASKSGSIDDSFTDFQEMPASSKTSNSQHGNSAPSLLIPFPGTKASTDKYAVFKGISTDKPSENPASFGESGDKYSAFRELEQTTDSKPLGESFAEFRSTGTDDGFTDFKTADSVSPLEPPTKDTFPSAFASGAAQQTQTQVKTPLNLEDLDMFSSVDCSGEKQVPFSATFSTAKSVSTRPQPAGSAAASAALASTKTSSLADDFGEFNLFGEYSNPASAGEQDDFADFMAFGNSSISSEPKASDKYEALREEVSPSPLSSSTVEGAQHPPAAATKYDVFKQLSLEGAGLAMEEFKENTSSTKSEDDFADFHSSKFSSTSSDKSLGEKAVAFRHAKEDSSSVKSLDLPSIGGSSVGKEDSEDALSVQFDMKLADVGGDLKHVMSDSSLDLPTVSGQHPPAADTEDLSCAAFGSCSSHFTVSTLTSCEWSDRADALQGRKLSPFVLSAGSRSFSATSNLHTKEISFGSSENITMSSLSKGSALASEDALPETAFPAFASFKDMMPQTTEQKEFESGDFQDFTRQDMPTVDRSQETSCPSPASSVASHETPKEGADDFGEFQSEKSKISKFDFLVANSQSKMKSSEEMIKSELATFDLSVQGSHKRSLSLGDKEISRSSPSPALEQPFRDRSNTLSERAALPVIRDKYKDLTGEVEENERYAYEWQRCLGSALDVIKKANDTLNGISSSAVCTEVIQSAQGMEYLLGVVEVYRVTKRVELGIKATAVCSEKLQQLLKDIDKVWNNLIGFMSLATLTPDENSLDFSSCMLRPGIKNAQELACGVCLLNVDSRSRKEETPAEEQPKKAFNSETDSFKLAYGGHQYHASCANFWINCVEPKPPGLLLPDLL
What is the function of this protein?
Plays a role in endocytosis and/or membrane trafficking at the trans-Golgi network (TGN) (By similarity).  May act by linking the adapter protein complex AP-1 to other proteins (By similarity).  Component of clathrin-coated vesicles (By similarity).  Component of the aftiphilin/p200/gamma-synergin complex, which plays roles in AP1G1/AP-1-mediated protein trafficking including the trafficking of transferrin from early to recycling endosomes, and the membrane trafficking of furin and the lysosomal enzyme cathepsin D between the trans-Golgi network (TGN) and endosomes (By similarity).
What are the official names of this protein?
Synergin gamma, AP1 subunit gamma-binding protein 1, Gamma-synergin.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Cytoplasm, perinuclear region. Cytoplasmic vesicle, clathrin-coated vesicle. Note=Localization at clathrin- coated vesicles depends on AFTPH/aftiphilin (By similarity). Associates with membranes via the adapter protein complex AP-1 (By similarity). Colocalizes with AP1G1 (By similarity).
Protein: TRPD_PSEFS
Sequence: MDIKTALSRIVGHLDLSTAEMSDVMREIMTGQCTDAQIGAFMMAMRMKSESIDEIVGAVSVMRELADKVELKTLDGVVDVVGTGGDGANIFNVSTASSFVVAAAGCTVAKHGNRAVSGKSGSADLLEAAGIYLNLTPVQVARCIDNVGIGFMFAQSHHGAMKHAAGPRKDLGLRTLFNMLGPLTNPAGVKHQVVGVFSQALCRPLAEVLQRMGSKHVLVVHSKDGLDEFSLAAPTFVAELKNDQITEYWVEPEDLGMKSQSLHGLAVESPAASLELIRDALGRRKTENGQKAAEMIVLNAGAALYAADHAYSLKEGVALAHDALHTGLAREKLEELGAFTAVFKMENEG
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: QUEC_STAAT
Sequence: MESVLNNEKAIVVFSGGQDSTTCLFYAKKHFKEVELVTFNYGQRHDTEIEVAKQIAQDQGMKHHVLDMSLLSQLTPNALTQHDMEITNNEDGIPNTFVPARNLLFLSFAGALAYQIGAKHIITGVCETDFSGYPDCRDSFIKSMNVTLSLAMDKDFVIHTPLMWLNKAETWKLSDELEVLDYIRTKTLTCYNGIIGDGCGECPACHLRQRGLNQYLESKGAL
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: MOBA_PSEPG
Sequence: MPDAFPPCSILILAGGRGQRMGGRDKGLIDWQGEPLVAHVQRVVRPLSDDLVISCNRNQEAYRAYADQVVGDAEADFPGPLAGVIAGLKVARHEWVVLLACDAPRVDQVLIEDLLRLAKANDSAAMVRQGEYWQPMFSVLPKRVLPVLEQAWAAGERSLQKALLREAVQGLACADDDCRLSNFNSPELLQG
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREF_STAAT
Sequence: MIDHTHLRLFQFCDSQFPTGAFSHSFGLETYIQRNIIHDDHTFIAWLKMFLQEQLTYSDGLAMRLVYDALENDDTQKVLHIDKLMFVQNLPKETRVGAKQMGTRMVKLALELYNSPWIAWYHQQMQDKKAKLNPAICFTMLGHHLGVDIETIIDYYLYQNVSSLTQNAVRAIPLGQTAGQKIVTHMIPYIEGTRKQIFELKEADFGMTAPGLELNQMAHENVNVRIFIS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARCH_THEVO
Sequence: MTYEILDHESDIGIMVYGTTYEELFSNAVYAMADLILDVGKLKEKRKMHEIIRGNTPEDIMVNLLSRVLFYVDTYYTLYFRATCKYEDSTLDVYLYGSEIPEEVEYRNVIKAVTYSEIAVKPEDGFARVIFDL
What is the function of this protein?
Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB.  Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation.  Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently (By similarity).
What are the official names of this protein?
Protein archease.
What is the protein family that this protein belongs to?
Belongs to the archease family.
Protein: RL1_ARTS2
Sequence: MAKRSKAYEAAAAKIDAEKFYAPFEAVTLAKDTNPSKFDATVEVAFRLGVDPRKADQMVRGTVNLPHGTGKVARVLVFATGDKAEAAIAAGADFVGSDDLIEKIAAGWTDFDAAVATPDLMGKVGRLGKVLGPRNLMPNPKTGTVTPDVTKAVNDIKGGKIDFRVDKHSNLHFIIGKVSFDAIKLAENYAAALEEVLRLKPSASKGRYIQKATVATTFGPGISVDPNVTKVLTEV
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.