PharMolix/UniProtQA huggingface dataset:
Protein: THG1_CANGA
Sequence: MAKSKYEYVKQFESHDTLLPQCYIVVRIDGKKFHEFSKYYDFKKPNDERALKLMNACAKNVVLQYRHEMILAYGESDEYSFVLKKDTELYKRRRDKLSTLIVSLFTSNYVALWSKFFPGTNLHPKHLPFFDSRCVIYPNLETIRDYVTWRYVDTHINNLYNTAFWQLIQKCGMNPQEAEKRLSGTVSSEKNEILFKECGINYNNEPEMYKKGSLITNKGEILHINVIDSLDSLFEGY
What is the function of this protein?
Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.
What are the official names of this protein?
tRNA(His) guanylyltransferase, tRNA-histidine guanylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(His) guanylyltransferase family.
Protein: ASNA_YERE8
Sequence: MKKQFIQKQQQISFVKSFFSRQLEQQLGLIEVQAPILSRVGDGTQDNLSGSEKAVQVKVKSLPDATFEVVHSLAKWKRKTLGRFDFGADQGIYTHMKALRPDEDRLSAIHSVYVDQWDWERVMGDGERNLAYLKSTVNKIYAAIKETEAAISAEFDIKPFLPEQIHFIHSESLRAKFPDLDAKGRERAIAKELGAVFLIGIGGKLADGKSHDVRAPDYDDWTSPSAEGFAGLNGDIIVWNPVLEDAFEISSMGIRVDAEALKRQLALTSDEDRLKLEWHQSLLNGEMPQTIGGGIGQSRLVMLLLQQQHIGQVQCGVWGPEISEKVEGLL
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_PROMT
Sequence: MSNEGKPLQLTESKKIDAKSGEKEKALSLVVGQIERNFGKGSIMRLGDASKMRVETISTGALTLDLALGGGYPKGRVIEVYGPESSGKTTLTLHAIAEIQRNGGVAAFVDAEHALDPVYAASLGVDVENLLVSQPDTGEMALEIVDQLIRSAAVDLVVVDSVAALTPRSEIEGEMGDHSVGAQARLMSQAMRKITGNIGKSGCTVIFLNQLRLKIGITYGNPETTTGGNALKFYASVRLDIRRIQTLKRGTEEYGIRAKVKVAKNKVAPPFRIAEFDILFGKGISTLGCLLDLADETNVVTRKGAWYSYEGDNIGQGRDNTITWLEQNPESKEIIEKLVKEKLTEGSEVSANSMRPLASAARQASSRPNLSQVSANG
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3455_MYCBO
Sequence: MSRVQISTVLAIDTATPAVTAGIVRRHDLVVLGERVTVDARAHAERLTPNVLAALADAALTMADLDAVVVGCGPGPFTGLRAGMASAAAYGHALGIPVYGVCSLDAIGGQTIGDTLVVTDARRREVYWARYCDGIRTVGPAVNAAADVDPGPALAVAGAPEHAALFALPCVEPSRPSPAGLVAAVNWADKPAPLVPLYLRRPDAKPLAVCT
What are the official names of this protein?
Uncharacterized protein Mb3455c.
What is the protein family that this protein belongs to?
To M.leprae ML0378.
Protein: DHI1L_HUMAN
Sequence: MKVLLLTGLGALFFAYYWDDNFDPASLQGARVLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRSSTSRPRQPEHRGVPLQSQTAMFLPPTVPGARTLTETPLRGWPQPKMKSSRQKSKTEKNDGHLEPVTAWEVQVPRVRRLCRGLARPHLFGHD
What are the official names of this protein?
Hydroxysteroid 11-beta-dehydrogenase 1-like protein, 11-beta-hydroxysteroid dehydrogenase type 3, 11-DH3, 11-beta-HSD3, Short chain dehydrogenase/reductase family 26C member 2, Short-chain dehydrogenase/reductase 10.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Secreted.
Protein: DPH1_MOUSE
Sequence: MAALVVSETAEPGSRVGPGRGRISRGRLANQIPPEVLNNPQLQAAVQVLPSNYNFEIPKTIWRIQQAQAKKVALQMPEGLLLFACTIVDILERFTEAEVMVMGDVTYGACCVDDFTARALGVDFLVHYGHSCLVPMDTSVQDFRVLYVFVDIRIDTAHLLDSVRLTFTPGSSLALVSTIQFVSTLQAAAQELKADYHISVPQCKPLSPGEILGCTSPRLSKEVEAVVYLGDGRFHLESVMIANPNIPAYRYDPYGKVLSREYYDHQRMQATRQEAIAAARSAKSWGLILGTLGRQGSPKILEHLESQLRNLGLPFVRLLLSEIFPSKLSLLPEVDVWVQVACPRLSIDWGSAFPKPLLTPYEAAVALKDISWQQPYPMDFYSGSSLGPWTVNYGRDRAPRGLCQPASDKVQQGSRGGSPAPACESCNCADQKATSPAP
What is the function of this protein?
Catalyzes the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2 (PubMed:15485916, PubMed:24895408).  DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase (By similarity).  Acts as a tumor suppressor (PubMed:14744934, PubMed:15661533, PubMed:24895408).
What are the official names of this protein?
2-(3-amino-3-carboxypropyl)histidine synthase subunit 1, Diphthamide biosynthesis protein 1, Diphtheria toxin resistance protein 1, Ovarian cancer-associated gene 1 protein homolog, S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the DPH1/DPH2 family. DPH1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Punctate, primarily perinuclear localization.
Protein: IHFA_BRUSI
Sequence: MGGKTVTRADLVEAVYRKVGLSRTESAALVEMILDEVCDAIVNGETVKLSSFATFQVRDKNERIGRNPKTGEEVPILPRRVMTFKASNVLKQRILQEHQKRQGKTSK
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: CFA20_CHLRE
Sequence: MFKNAFQSGFLSVLYSIGSKPLEIWDKQVSNGHIKRITDADIQSSVLEIMGQNVSTTYITCPADPNKTLGIKLPFLVLIIKNLNKYFSFEVQVLDDKNVRRRFRASNYQSTTRVKPFICTMPMRLDSGWNQIQFNLSDFTRRAYGTNYIETLRVQVHANCRIRRIYFSDRLYSEEELPAEFKLFLPIQKS
What is the function of this protein?
Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility (PubMed:24259666, PubMed:24574454).  Involved in the control of flagellar beating in an asymmetric and planar waveform (PubMed:24259666, PubMed:24574454).  Stabilizes outer doublet microtubules (DMTs) of the axoneme and may work as a scaffold for intratubular proteins, such as tektin and PACRG, to produce the beak structures in DMT1, 5 and 6 (PubMed:24259666, PubMed:24574454).  Not essential for flagellar assembly (PubMed:24574454).
What are the official names of this protein?
Cilia- and flagella-associated protein 20, Basal body up-regulated protein 22, Bug22p, Flagellar-associated protein 20.
What is the protein family that this protein belongs to?
Belongs to the CFAP20 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, flagellum axoneme. Cytoplasm, cytoskeleton, flagellum basal body. Note=Localizes predominantly along the length of all nine axonemal outer doublet microtubules (DMTs). Localizes to the inner junction (IJ) between A- and B-tubules of the DMTs. Associates to the basal bodies in a microtubule-dependent manner. Enters into the flagella through diffusion.
Protein: RS211_CHESB
Sequence: MQVLVRDNNVDQALRALKKKMQREGIFREMKMRGHYEKPSEKRAREKAEAVRRARKLARKRAQREGLVSGRPAAAR
What are the official names of this protein?
30S ribosomal protein S21 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: CHUR_PONAB
Sequence: MCGDCVEKEYPNRGNTCLENGSFLLNFTGCAVCSKRDFMLITNKSLKEEDGEEIVTYDHLCKNCHHVIARHEYTFSIMDEFQEYTMLCLLCGKAEDTISILPDDPRQMTLLF
What is the function of this protein?
Transcriptional activator that mediates FGF signaling during neural development (By similarity).  Plays a role in the regulation of cell movement (By similarity).  Does not bind DNA by itself (By similarity).
What are the official names of this protein?
Protein Churchill.
What is the protein family that this protein belongs to?
Belongs to the Churchill family.
Protein: HIS51_CAMJE
Sequence: MIALIDYKAGNLNSVAKAFEKIGAINFIAKNPKDLQKADKLLLPGVGSFKEAMKNLKELGFIEALKEQVLVQKKPILGICLGMQLFLERGYEGGVCEGLGFIEGEVVKFEEDLNLKIPHMGWNELEILKQVPLYQGIDNKSDFYFVHSFYVKCKDEFVSAKAQYGHKFVASLQKDHIFATQFHPEKSQNLGLKLLENFARL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity).
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH 1, IGP synthase glutaminase subunit 1, IGP synthase subunit HisH 1, ImGP synthase subunit HisH 1, IGPS subunit HisH 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PKS2_DICDI
Sequence: MIESTSNKSRDVAVIGIGLRLPGGSNTPLELWNNLIKGIDGIVETKERWSDTFSEMGEVSSKYAGLIDFDQWMSFDPLHFAINPSDAKEIDPQQKILLKTTWEAFEDAQIDPLSLRGSDTSVYVGASSMDYASINTDPNKQPINCFNVNLSGVSNRISYCYDLRGTSLTIDTACSSSLNAVHLGYESIVNGKSDYSIVGGVNFIINPQQSRAFKYAMVTSKTGKCKAFDESADGFVRSEGAVVLILKSLSKSIEDGNQIYSIIKGSSSNVDGTLNKTNYFAPSKVSQSNNMQKAFDSTNGELTPNDISFFELHGTGTQIGDPIEVEAVSTLFKDIKTKESPLLIGSIKSNIGHLEPASGVASLAKVCLMLKNREFVKNIHFETPNPNIKFDEWKVKVCTQNTPFPTIRGKPISIAINSFGITGSNACLLLSEYLKTNITTTNDQLEPSTTSYLIPLSSSSKKSLELYKNELTNNIETFSKSIEFKDFISYHINSKAIKLASRSVLMVKDWDELKSSLNLNEPLIYSSKGNKSGNIMKDNNKNPILVFVFCGIGGQWNQMGKQLYETSKVFKQSIDEIDQIFNRLFGYSILKKLRSISDDDSKGINEFITSQPSIFMLQVSLFEFYKSWGINPSINVGHSFGEISSACCSGMLDLETACFIVYKRSIIQTKTIGSGGMLVIGLSEDEYKKQYQSQYPLIEISCFNSPSSIVISGSELDLTTITSSLKEKNIFTYLLGSPAALHSSKQKVIKDDILTQLKDIKFKQPTIKTFSTVTTNLFDNSTTPFDSNYIFSNIRKPVSFEKTIKNIFNHIETNDLGSNVIFLELSPLPTLTNYIKEMIPQNSNYFYIDDESITILTSLNKKKSIDELQEIKSTISQIYCSGYNVNFKSQLTTTTTTTFGNLIIDSNKIVKGFTSYYLPRYQWDESNYFKVGRISKQISQGPTATQLGYRNDVSPFMSYTSYIDIKEEPFKFLKCHQSRGRNLFPGNAYLENVLKVFPDQDLTFHLIEYRSPLILKEGIKHIISTNIYPSAKNEYRVTFHYKDSFDKWILGCSARFSVLKHNSDLENQKIDVESLKAKCNWTTIKRKEFYEVLKTNTSLALTGQFQCIEEAYYGYNCCLAKISMNETLTKLSQYDNELFLNACTIDGGFQLLGLFRDNPDTFVMDRVELLRFYASNIPKSSKFRENYPFIYTYTEFISQIGNSVYANINTFLPDGTLLFNTPVVCYSSISTDIKNQLSIENPNHQLYSTVLQSLESPLSVTTQNAIIDEKLFLSFLPTPVANIRKAFTTCIFSNIKKIYQSITPAKINTSTVDSLIDSYFKICETDNIEKRKLGETLFNALKLNYSIIEYSSQAKLIKLLSTNQIEIMNKITTHLLNETKPTTNTTETTPVSSSQKLPEQIQLIENIITKSVLPLVNEKIVFRILEISSGIGQLSKIIVTRLNELLQQNPLAEIDIELTFTDREDITLIKEKLTTLLYSTSSTADINSKDLSSRKTSLIFTQLDLNDKDLISSKTIYPSYYDIIVLNGLDGIKDLNQSIETIYQILNPNGYFIMIDTLFKANKSDLKNYELYQQWLSFNYFDSTKDLDSWKKLLTQDFKLINFTATSSQPWVILCQKPRFFETVSTENPISTTLSCYDQVIIFGTIDNINESKALSKLMDVNDRGTDIYCIKTLDEFETHVKETPLTDESVIVYVNTINQVFISFISYSLEYIKINQHLLRTNCNAKHVLLTRSAFIETTNTLVSATVGAFRYFCEFSQLDLYLMDFDDSIYLKSMQFINVTHEMTNPNKHYQREFIFRGDKVYYERVTQETNLKLKLKSTSYISEPTQLYAKLGQNLQYQLKPFENKIPEGFIEVKVLASGINFKDNLVYRRLVPNEAVNHTGNSNDPEFGYECSGIVSRVGDGVTKFKVGDEVVGLGFNCTGSFVTLEQFRFVLKPKNLTHVEAASIPVVYLTSYYSLFVAGYLSIEKKESVLIHGGTGGIGLACINLLKAKGFKGYLFVTVGSKEKENFLRVTYGNFITGIYSSQNTDYLLEIKKKIQQLTGNNLIFKQFGVAKMGIDLIINTLSNEFMDANFNSLCQGGRIIDLSVTHMNSQDTTDFRKFRYCISYSSVELLLNGFERNKLILQEVMDMFVNENLALLPIKEYSVKDIKEAIEFIAERKHIGKIVVNHENYDLISQTLVSNDNEFYKDFLIPKANYRISADCNLGKTVLLTGQLGLSLSIIKWIIAFNNLEQPVENILVLSLSPIKYELEHMICYCKHVNNQIKIIFKQVDISDMCALDDAIGEIYKENENLPLVSSIFHNAFAPSECDALDIDEDHLRISHSAKTMGMINLNSLSTGIWSESIKNFVLSSSITSILGSQRQCGYISANCIIDAVSRLRASEGLPCTSINWGVLGTGFVSRNESVSKLFEYQGFIPISMDMLIGTLDLFLQNSGKLNNKIVASFNYNNVSAAFRNHHLSYKLNYFLNPVYSKGSTFDDNELSIRDDILEKFSEYLSTEKSKLSLDIKLIDYGSSSIMLVELKNYLDKTYTPNILSIAQLQNVTINQLIQAVIQAVSKLKKPTTNQQSQQPIISNIKWEDEIALDPTIKPTQQIIDTYKNEMTQLYKNNNNKTSLGGLQVLLTGPCTFSGTHILSNLLLSSKTKVIHCLLPMETPEQVMCTIIDNFKAQGLYDQLNLANVLSKIKPIAADFTRPIFGLDTDDYIELSKKIDIVINAASNTTKHYCAHISYEDTNKEYLHGVSHLLRFASSEKLKRVVQISTLGRYSDLQRNSLDEYYFPEVDFSFISDQNQLVSGYIQSKIVAEYHLKQASNRGIPCLIVRTPFTFPGNNGIGREADFTQLLLQSCYTLNCYPTESHIQLYTAPVTWYAKNITLMAVGSDISQDGCWDTINTSPIENLLCFNLFGGGFDFGDLLVDISKDLSWKEVPFETLVKKAAVNETECCKRLASFVLKKKGDFLKNLGVIPGNFTVNENLKNYLTLNNSFDGWLVTKQLVYNHLSYVFKKKVF
What is the function of this protein?
Probable polyketide synthase.
What are the official names of this protein?
Probable polyketide synthase 2, dipks2.
Protein: SF3A1_MOUSE
Sequence: MQAGPVQAVPPPPPVATESKQPIEEEASSKEDPTPSKPVVGIIYPPPEVRNIVDKTASFVARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGKAQEPSAAIPKVMQQQQQATQQQLPQKVQAQVIQETIVPKEPPPEFEFIADPPSISAFDLDVVKLTAQFVARNGRQFLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFSKLKKEAENPREVLDQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTTPEELGARILIQERYEKFGESEEVEMEVESDEEDQEKAEETPSQLDQDTQVQDMDEGSDDEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPAMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPAAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPPSKKLKTEDSLMPEEEFLRRNKGPVSIKVQVPNMQDKTEWKLNGQGLVFTLPLTDQVSVIKVKIHEATGMPAGKQKLQYEGIFIKDSNSLAYYNMASGAVIHLALKERGGRKK
What is the function of this protein?
Involved in pre-mRNA splicing as a component of the splicing factor SF3A complex that contributes to the assembly of the 17S U2 snRNP, and the subsequent assembly of the pre-spliceosome 'E' complex and the pre-catalytic spliceosome 'A' complex.  Involved in pre-mRNA splicing as a component of pre-catalytic spliceosome 'B' complexes.
What are the official names of this protein?
Splicing factor 3A subunit 1, SF3a120.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle.
Protein: RS7_LACP3
Sequence: MPRKGSVAKRDVLPDPVYNSKLVTRLINHLMIDGKRGKASTILYDAFDMIKKQTGNEPLDVFEEAMKNVMPVLEVKARRIGGSNYQVPIEVRPDRRTTLGLRWIVQYSRQRGEHTMDERLAKEIMDAANNTGAAVKKREDTHKMADANRAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: CH601_ROSCS
Sequence: MPKQLYFNEEARRALKRGVDIVADAVKTTLGPRGRNVSIDKKFGAPTVTHDGVTVAKEIELKDPFENMGARLLVEVATKTNDVVGDGTTTATVLAQSIVNEGLKMVAAGANPMLIKRGLDKAVEAVVAELKSVAIPVRDRADIAHVAAISAADSEIGDLIAEVMEKVGKDGVITVEESKGIAFEKEYTEGMQIDRGYISPYFVTNPERMEAELEDPYILITDKKISSIQDILPVLEKALQVTKNLVIVAEDVDGEALATLVVNKLRGTINALAVKAPGFGDRRKAMLQDIAILTGGTLISEEIGRKLDSATIEDLGRARRVVSDKDNTTFIEGRGDERAIRARIEQIRAQIETTTSDFDREKLQERLAKLAGGVAVLKVGAATEPELKEKKHRVEDALSTARSAVEEGIVPGGGVALLTAIPALDRVQVTYEDEKYGVQILRRALEEPMRQLARNAGEDGAVIIDTVRRLQKEKNDKNIGYNVLTGEFGNMIEMGIIDPVKVTRSAVQNAVSIAGLLLTTEALIADIPEEKPAAPTPGGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 1, 60 kDa chaperonin 1, Chaperonin-60 1, Cpn60 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP3_EHDVA
Sequence: MAEPPDAATPKTSPYLKGDELSSDSGPLLSIFALQEIMQKVRQAKSEYMAATKDVDLTIPDVQKIIDGVKELASETIYKVVNKPLISYRHIVMQSRDRFLRVDTYYERMSEVGDKIDENEPAKFYETVIKKVRHLRTEGAFVLHNIPTRDHRGMEIADPEILGVDVKSILPVLTAEHRAMVQHILDGAIIENGIVATRDVDVYFGACSESVYRIYNRLQGYIEAVQLEELRAAITWLERLGRRKRMTFSQEFLTDFRRADTIWVLALQLPANPRVIWQVPRCSIANLIMNIATCLPTGEYVSPNPRIASITLTQRITTTGPFAILTGSTPTAQQLDDVRKIYLALMFPGQIVLDLKIDPGERMDPAVRMVAGVVGHLMFTAGPRFTNITQNMARQLDIALADFLLYMYNTRIQVQYGPTGEPLDFRIGRGQYDCNAFRTNFQTGAGYNGWGLVDVENREPAPYDHVQRFIRYCNIDSRELIHPATFGIGMNYYCYNEMLRMLVAAGKDTEAAFFRNMLPFHMVRFARINQIINEDLHSAFSMPDDQFNVLLANMIAGAQERMDPVVLDISWISIWYAFNRSFEPTRRNEMLESAPLIESVYASELTVMKIDMQQMALLQRRFPDVLIEARPTHFWKAVMEVSPEPVRAIMDLAHSHSFINIRDMMRWIGLPSMQPSMKLVLEEEAWAVANDFEELMLTDQVYMFRDMLPEPRLDDIERFRQEGFYYTNMLDGPPTIDRVVQYTYEVARLQANMGQLRAALRRIMDEEGWVRFGGVLRTVRVKFFDSRPPEEILQALPFDYQTSEKGGLTYATIKYANDTTIYYLIYNVEYSNLPDSLVLINPTYVMTKVFINKRIVERVRVGQALAVMNKRFIAYKGKMRIMDITQALKVGTKLAAPTV
What is the function of this protein?
The VP3 protein is one of the five proteins (with VP1, VP4, VP6 and VP7) which form the inner capsid of the virus.
What are the official names of this protein?
Core protein VP3.
What is the protein family that this protein belongs to?
Belongs to the orbivirus VP3 family.
What are the subcellular locations of this protein?
Virion.
Protein: GB_HHV2H
Sequence: MRGGGLICALVVGALVAAVASAAPAAPAAPRASGGVAATVAANGGPASRPPPVPSPATTKARKRKTKKPPKRPEATPPPDANATVAAGHATLRAHLREIKVENADAQFYVCPPPTGATVVQFEQPRRCPTRPEGQNYTEGIAVVFKENIAPYKFKATMYYKDVTVSQVWFGHRYSQFMGIFEDRAPVPFEEVIDKINTKGVCRSTAKYVRNNMETTAFHRDDHETDMELKPAKVATRTSRGWHTTDLKYNPSRVEAFHRYGTTVNCIVEEVDARSVYPYDEFVLATGDFVYMSPFYGYREGSHTEHTSYAADRFKQVDGFYARDLTTKARATSPTTRNLLTTPKFTVAWDWVPKRPAVCTMTKWQEVDEMLRAEYGGSFRFSSDAISTTFTTNLTEYSLSRVDLGDCIGRDAREAIDRMFARKYNATHIKVGQPQYYLATGGFLIAYQPLLSNTLAELYVREYMREQDRKPRNATPAPLREAPSANASVERIKTTSSIEFARLQFTYNHIQRHVNDMLGRIAVAWCELQNHELTLWNEARKLNPNAIASATVGRRVSARMLGDVMAVSTCVPVAPDNVIVQNSMRVSSRPGTCYSRPLVSFRYEDQGPLIEGQLGENNELRLTRDALEPCTVGHRRYFIFGGGYVYFEEYAYSHQLSRADVTTVSTFIDLNITMLEDHEFVPLEVYTRHEIKDSGLLDYTEVQRRNQLHDLRFADIDTVIRADANAAMFAGLCAFFEGMGDLGRAVGKVVMGVVGGVVSAVSGVSSFMSNPFGALAVGLLVLAGLVAAFFAFRYVLQLQRNPMKALYPLTTKELKTSDPGGVGGEGEEGAEGGGFDEAKLAEAREMIRYMALVSAMERTEHKARKKGTSALLSSKVTNMVLRKRNKARYSPLHNEDEAGDEDEL
What is the function of this protein?
Envelope glycoprotein that forms spikes at the surface of virion envelope.  Essential for the initial attachment to heparan sulfate moieties of the host cell surface proteoglycans.  Involved in fusion of viral and cellular membranes leading to virus entry into the host cell.  Following initial binding to its host receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.  May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress.
What are the official names of this protein?
Envelope glycoprotein B, gB.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein B family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN).
Protein: SURE_THISH
Sequence: MRILLSNDDGVHAPGLQCLAAALRTVAEVHVVAPDRDRSGASNSLTLARPLRAMRLDNGDVRVDGTPTDCVHLAITGLMEEEPDMVISGINSGANMGDDVLYSGTVAAAMEGRFLGLPAIAVSINSHEGKHYDSAARAVLDLLKRLGHMPLPANTILNVNVPHLPWSEIQGVQATRLGHRHKSEPMIRSHDPRGRPIYWVGAAGPEQDAGPGTDFHAVRSGYVSVTPIQVDLTRYDAIDTVANWLRDEDPA
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSPD2_DICD3
Sequence: MLGKGIKKSWGWLGLTVLLLGSPCGWAAEFSASFKGTDIQEFINTVSKNLNKTVIIDPTVRGTISVRSYDMMNEGQYYQFFLSVLDVYGFSVVPMDNGVLKVIRSKDAKSSSIPLANNEQPGIGDELVTRVVPLNNVAARDLAPLLRQLNDNAGAGTVVHYEPSNVLLMTGRAAVIKRLVDIVNTVDKTGDREMVTVPLTYASAEDVAKLVNDLNKSDEKNALPSTMLANVVADGRTNSVVVSGEENARQRAVEMIRQLDRKQVVQGGTKVIYLKYAKALDLIEVLAGNGTSGNRNSSSSNASRPSSPRSGSSSNSNSSSGSSGSSSGSSSSSSSSSSMGFGSAFGSTSSSGGRTITIQGKEVTVRAHDQTNSLIITAPPDIMRDLEQVINQLDIRRPQVLVEAIIAEIQDADGLNLGIQWANKRAGMTQFTNTGIPISTAVIGTDQFRSNGTLTTAYASALSSFNGVTAGFYRGNWSMLLTALSSDSKNDVLATPSIVTLDNMEATFNVGQEVPVLTGSQTTSADNIFNTVERKTVGIKLRVKPQINEGDSVLLQIEQEVSSVADSNSSTNSSLGVTFNTRTVNNAVMVTNGETVVVGGLLDKTSVESNDKVPLLGDIPWLGSLFRSKSQEVRKRNLMLFLRPTIIRDPGQFQEASINKYRSFNNEQQQQRGEGNGVLDNNTLRLSGGNTYTFRQVQSSISDFYKPEGR
What is the function of this protein?
Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity).  Required for the translocation of the multiple pectic enzymes (Probable).  This subunit forms the outer membrane channel (By similarity).
What are the official names of this protein?
Secretin OutD, General secretion pathway protein D, Pectic enzymes secretion protein OutD, Type II secretion system protein D, T2SS protein D.
What is the protein family that this protein belongs to?
Belongs to the bacterial secretin family. GSP D subfamily.
What are the subcellular locations of this protein?
Cell outer membrane. Note=Most of the protein is in the periplasm which it traverses to contact proteins of the cell inner membrane.
Protein: Y1903_STAAC
Sequence: MNALFIIIFMIVVGAIIGGITNVIAIRMLFHPFKPYYIFKFRVPFTPGLIPKRREEIATKIGQVIEEHLLTETLINEKLKSEQSQQAIESMIQQQLQKLTKDQLSIKQITSQIDIDLEQVLQTNGNQYIESQLNNYYTKHQNQTIASLLPNQLVTFLNQHVDNATDLLCDRARNYLSSAKGTQDINDMLDTFFNEKGKLIGMLQMFMTKESIADRIQQELIRLTSHPKARTIVTSLITNEYQTFKDKPLNELLDASQFNEIAENLSVYVTTYASKQANKPVVTLMPQFVDYLEGQLSSKLANLIIEKLSIHLSTIMKKVDLRGLIEEQINTFDLDYIEKLIIEIANKELKLIMSLGFILGGIIGFFQGLVAIFV
What are the official names of this protein?
UPF0754 membrane protein SACOL1903.
What is the protein family that this protein belongs to?
Belongs to the UPF0754 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AT5G3_BOVIN
Sequence: MFACAKLACTPALIRAGSRVAYRPISASVLSRPETRTGEGCTVFNGTQNGVSQLIQREFQTTAVNRDIDTAAKFIGAGAATVGVAGSGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMVAFLILFAM
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
What are the official names of this protein?
ATP synthase F(0) complex subunit C3, mitochondrial, ATP synthase lipid-binding protein, ATP synthase membrane subunit c locus 3, ATP synthase proteolipid P3, ATPase protein 9, ATPase subunit c.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: SJ381_SCHJA
Sequence: MNTCIQLLILCLVTVINSENSTDNSTENTIKNETENATETELPETFENETENVSETELPEIIENETKIEALNLPQIPKQKYCRTEGQYCSRTYFHRCCGNLVCQLHGFFNGTCVQCLAERKFCIWSSECCSKRCRLFRCRKNPYVQVIPY
What are the official names of this protein?
UPF0506 protein SJCHGC02381.
What is the protein family that this protein belongs to?
Belongs to the UPF0506 family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRMD_BACFR
Sequence: MRIDIITVLPEMIEGFFNCSIMKRAQDKGLAEIHIHNLRDYTEDKYRRVDDYPFGGFAGMVMKIEPIERCINTLKAERDYDEVIFTTPDGEQFDQKMANSLSLSGNLIILCGHFKGIDYRIREHLITKEISIGDYVLTGGELAAAVMADAIVRIIPGVISDEQSALSDSFQDNLLAAPVYTRPAEYKGWKVPEILLSGHEAKIKEWELQQSLERTRRLRPDLLED
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.