PharMolix/UniProtQA huggingface dataset:
Protein: NTPP_RICCN
Sequence: MKQNRKNLPIILASSSPARIELLNRIKIIPSQIIPADIDETPNLRELPAPLAIRLAYEKAIKIASQIEESAIIIAANTVAAVGRRILPKATTYEEVKNCIKMLSGRRHRIYTGLCIIKKENDQLTVRQKIVQTIVKFKKLSDEEINFYCSLDEGIDKAGGCKISGYAEAFISFISGSYSNVMGLPLFETVNALTSLGFRCSSIMPAKMNYCHSAT
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FB207_ARATH
Sequence: MDSEKMDLFSKLPDEVISHILSSLPTKEAASTSVLAKKWRYLFAFVPSLDFNDSDFLHPQEGKREKDGILRSFMDFVDRVLALQGASPIKKFSLNVKTGVDPDRVDRWICNVLQRGVSHLALFMDFEEEYSLPYEISVSKTLVELKTGYGVDLYLWDDDMFLPMLKTLVLESVEFGRGQFQTLLPACPVLEELMLLNMEWKDRNVILSSSSLKNLKITSEDGCLGTLSFDTPNLVFLDYYDYVAEDYPIVNLKNLVEVGINLVLTADRINRARDNVWNLIHGIQNAEIFHISPVTFEVLSLSCEAMPVFKNLTTLNIRTVMQQGWQAMPLLLKNCPNLETLYLGGLLHTVTNKCGDVCDCIPRKKKGRSLMACPVNKIQIQGFRGTIREVHMIKHFLDFCPSLKEMEIIVETKEPTLFEIPKWLEIVEDTLMQYNEMSSCTINYRVLAPLYWRWTRK
What are the official names of this protein?
Putative F-box protein At3g58860.
Protein: FPP1_ARATH
Sequence: MEKRKRESSERSFGESESVSSLSEKDSEIQPESTMESRDDEIQSPTVSLEVETEKEELKDSMKTLAEKLSAALANVSAKDDLVKQHVKVAEEAVAGWEKAENEVVELKEKLEAADDKNRVLEDRVSHLDGALKECVRQLRQARDEQEQRIQDAVIERTQELQSSRTSLENQIFETATKSEELSQMAESVAKENVMLRHELLARCEELEIRTIERDLSTQAAETASKQQLDSIKKVAKLEAECRKFRMLAKSSASFNDHRSTDSHSDGGERMDVSCSDSWASSTLIEKRSLQGTSSSIELDLMGDFLEMERLVALPETPDGNGKSGPESVTEEVVVPSENSLASEIEVLTSRIKELEEKLEKLEAEKHELENEVKCNREEAVVHIENSEVLTSRTKELEEKLEKLEAEKEELKSEVKCNREKAVVHVENSLAAEIEVLTSRTKELEEQLEKLEAEKVELESEVKCNREEAVAQVENSLATEIEVLTCRIKQLEEKLEKLEVEKDELKSEVKCNREVESTLRFELEAIACEKMELENKLEKLEVEKAELQISFDIIKDKYEESQVCLQEIETKLGEIQTEMKLVNELKAEVESQTIAMEADAKTKSAKIESLEEDMRKERFAFDELRRKCEALEEEISLHKENSIKSENKEPKIKQEDIETAAGKLANCQKTIASLGKQLQSLATLEDFLTDTPIIPMAANGVSSSSNSESWKVHKNETFMTRNHPESIKPTKETSPSSSSSTASAAVSMPVSTNRGSSEKNRNGFATVFTRSKDGIHLAI
What are the official names of this protein?
Filament-like plant protein 1, AtFPP1.
What is the protein family that this protein belongs to?
Belongs to the FPP family.
Protein: EXOB_RHIME
Sequence: MQNNNILVVGGAGYIGSHTCLQLAAKGYQPVVYDNLSNGHEEFVKWGVLEKGDIRDRQRLDEVLARHKPRAILHFAAMIEVGESVKDPAAFYDNNVIGTLTLLSAALAAGIDAFVFSSTCATYGLPDSVPMDESHKQAPINPYGRTKWICEQALKDYGLYKGLRSVILRYFNAAGADFEGRIGEWHEPETHAIPLAIDAALGRREGFKVFGTDYDTRDGTCVRDYIHVLDLADAHVRAVDYLLEGGESVALNLGTGTGTTVKELLDAIEKVAKRPFNIGYAERREGDSTTLVANNDKARQVLGWEPQYDLAAITESAWNWHSRRNQGG
What are the official names of this protein?
UDP-glucose 4-epimerase, Galactowaldenase.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family.
Protein: NREC_STAES
Sequence: MKIVIADDHAVVRTGFSMILNYQEDMEVVATAADGVEAYQKVLEHRPDVLILDLSMPPGESGLIATSKISESFPETKILILTMFDDEEYLFHMLKSGAKGYILKNSPDEQLILAVRTVYQGETYVDMKLTTSLVNEFVNQSQTDEVSSSSDPFKILSKRELEILPLIAKGYGNKDIAEKLFVSVKTVEAHKTHIMTKLNLKSKPELVEYALKKKLLEF
What is the function of this protein?
Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen.  Phosphorylated NreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT, and activates their expression (By similarity).
What are the official names of this protein?
Oxygen regulatory protein NreC, Nitrogen regulation protein C.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_LEIXX
Sequence: MTTATAEAQASTAQPAGVGRIARVTGPVVDIEFPHDSIPGIYNALKTTITIGDRSTEITLEVAQHLGDDLVRAISLKPTDGLVRGGEVRDTGSLITVPVGDVTKGKVFDVTGEILNAEPGEKIEIAERWPIHRQPPSFDHLESKTQLFETGIKVIDLLTPYVQGGKIGLFGGAGVGKTVLIQEMVQRVAQDHGGVSVFAGVGERTREGNDLIHEMEEAGVFDKTALVFGQMDEPPGTRLRVALSALTMAEYFRDVQKQDVLLFIDNIFRFTQAGSEVSTLLGRMPSAVGYQPNLADEMGLLQERITSTRGHSITSLQAIYVPADDYTDPAPATTFAHLDATTELSREIASKGLYPAVDPLTSTSRILDPRYLGADHYRVATTVKQILQKNKELQEIIAILGVDELSEEDKITVSRARRIQQFLSQNTYMAKKFTGVEGSTVPLKETIESFDAIAKGEFDHVAEQAFFNVGALSDVEEKWAQIQKENG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SRP19_METST
Sequence: MKTIIWPTYINSEHSRGEGRKLSLEESVEEPKIREISQSLKKLKIQYVVEHNKSYPGSWWEKSGRVVVEQEDMTKLELLRAIAKNIKNSRNN
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
What are the official names of this protein?
Signal recognition particle 19 kDa protein, SRP19.
What is the protein family that this protein belongs to?
Belongs to the SRP19 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROBQ_OLEEU
Sequence: MSWQAYVDDHLMCDIEGHEGHRLTAAAIVGHDGSVWAQSATFPQFKPEEMNGIMTDFNEPGHMAPTGLHLGGAKYMVIQGEAGAVIRGKKGSGGITIKKTGQALVFGIYEEPVTPGQCNMVVERLGDYLDEQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity).
What are the official names of this protein?
Profilin-3, Pollen allergen Ole e 2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: Y4TK_SINFN
Sequence: MPTMKILTEGELRQIVPLDLDAVKCTEDAFRALAVPNAVKMPPILRLDVPDSRGEVDVKTAYIPGLGGFAIKISPGFFDNPKIGLPSTNGMMVLLSSQTGLVQALLLDNGYLTDVRTAAAGAVAAKHLSQQDASVATIFGAGVQARLQLRALTLVRPIRQARIWARDQLKAEALVEQLKLEHSFAISASDDPRQAVSGAHIVVTTTPADRPILVASWLEAGQHVTAMGSDAEHKNELDPAAIARADVYVADSLTQTRRLGELHHAIEAGLIARDAAFPELGEVIAGVKTGRTRESDITIADLTGTGVQDTAIATLAFQRAEERSAGSLFES
What are the official names of this protein?
Uncharacterized cyclodeaminase y4tK.
What is the protein family that this protein belongs to?
Belongs to the ornithine cyclodeaminase/mu-crystallin family.
Protein: FPG_RICM5
Sequence: MPELPEVETLKNSLKDKLIGLIVENVELKRDNLRYKLSPLLATEILNTNILDVRRRAKYLIIDFNNDYSLIVHLGMSGRFTLQSANYKTQKHDHVIFDLSNGEKLIFNDTRRFGMIYSFKTDLLEQEFFNDLGIEPFSDLLTLEYLKDKLQTRKRPIKNLIMDNRVIVGVGNIYASESLHLARIHPDKSGSDLRDDEIENLIKSIRDVLTKAITAGGTTLKDFVNGDNKPGYFTQQLTVYGKEGQSCLSCSSTIIKTKHSGRSTFYCKTCQYRLASFTI
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: LPXD_ECOL5
Sequence: MPSIRLADLAQQLDAELHGDGDIVITGVASMQSAQTGHITFMVNPKYREHLGLCQASAVVMTQDDLPFAKSAALVVKNPYLTYARMAQILDTTPQPAQNIAPSAVIDATAKLGNNVSIGANAVIESGVELGDNVIIGAGCFVGKNSKIGAGSRLWANVTIYHEIQIGQNCLIQSGTVVGADGFGYANDRGNWVKIPQIGRVIIGDRVEIGACTTIDRGALDDTVIGNGVIIDNQCQIAHNVVIGDNTAVAGGVIMAGSLKIGRYCMIGGASVINGHMEICDKVTVTGMGMVMRPITEPGVYSSGIPLQPNKVWRKTAALVMNIDDMSKRLKSLERKVNQQD
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-(hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase, UDP-3-O-(3-OHC14)-GlcN N-acyltransferase, UDP-3-O-(3-hydroxytetradecanoyl)glucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: Y4300_HAEIE
Sequence: MQLEPNFWQTKSLLEMTESEWEALCDGCGKCCYRKYIQGRGKRQKLYYTRIACNLLDLETGKCGNYSERFNIETDCTKLTKKNLPDFHWLPDTCAYRLLYEGKTLPEWHPLISGSPHSVKNADILIKNGIHERDVIDWFEFIIDEDHTFK
What are the official names of this protein?
UPF0260 protein CGSHiEE_04300.
What is the protein family that this protein belongs to?
Belongs to the UPF0260 family.
Protein: RS3_ALKEH
Sequence: MGHKVHPTGFRLGVTEDWRSMWYAGSSNFGEYLNTDLQVRNFIRKKLAHASVSRIRIERPAKNALVTIHTARPGIVIGKKGEDIDRLRGEVARLMGVPVHINIEEIRKPELDAKLVAESVAQQLERRIMFRRAMKRAVGNAMRLGAQGIKVHVSGRLNGAEIARSEWYREGRVPLHTLRANIDYGVAEAHTTYGVIGVKVWVFKGEIIDSDAQPAAGGEGARQGKG
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: THII_BACC7
Sequence: MMTYEYILVRYGEMTTKGKNRSKFVSTLKDNVKFKLKKFPNIKIDATHDRMYIQLNGEDHEAVSERLKDVFGIHKFNLAMKVPSELEDIKKGALAAFLQVKGDVKTFKITVHRSYKHFPMRTMELLPEIGGHILENTEDITVDVHNPDVNVRVEIRSGYSYIMCDERMGAGGLPVGVGGKVMVLLSGGIDSPVAAYLTMKRGVSVEAVHFHSPPFTSERAKQKVIDLAQELTKYCKRVTLHLVPFTEVQKTINKEIPSSYSMTVMRRMMMRITERIAEERNALAITTGESLGQVASQTLDSMHTINEVTNYPIIRPLITMDKLEIIKIAEEIGTYDISIRPYEDCCTVFTPASPATKPKREKANRFEAKYDFTPLIDEAVANKETMVLQTVEVVAEEEKFEELF
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIR_PSECL
Sequence: MSVFRSVLGACVLLGSCASSLALAGGAEGLQRVKVDLVAPPLVHPHEQVVSGPPKVVQFRMSIEEKKMVIDDQGTTLQAMTFNGSMPGPTLVVHEGDYIELTLVNPATNSMPHNVDFHAATGALGGAGLTQVVPGQEVVLRFKADRSGTFVYHCAPQGMVPWHVVSGMNGALMVLPRDGLRDPQGKLLHYDRVYTIGESDLYIPKDKDGHYKDYPDLASSYQDTRAVMRTLTPSHVVFNGRVGALTGANALTSKVGESVLFIHSQANRDSRPHLIGGHGDWVWTTGKFANPPQRNMETWFIPGGSAVAALYTFKQPGTYVYLSHNLIEAMELGALAQIKVEGQWDDDLMTQVKAPGPIVEPKQ
What are the official names of this protein?
Copper-containing nitrite reductase, Cu-NIR.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: UREF_SHEHH
Sequence: MYSAHCMLPELRLYQLISPSLPVGGFTYSQGLEWAIDKGWVTTATELENWLKSQMLESLTCLELPVLVRIQGYLAANDYAQAQAWCNYLAASRETKELRLEEHQRGIAFVRLLPKLGIALTSELTTMVKTSQLAAFALGINQWQIPLDKALGGYLWSWLENAVVVGIKLVPLGQSAGQQLLMSLAENIPAAVEKALLITDQEVGSFTPAQVMASCRHEHQYTRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYA_METRJ
Sequence: MSGVNEIRSTFLDYFAKAGHEVVPSSSLVPKNDPTLMFTNAGMVQFKNVFTGMEKRAYDRATTAQKCVRAGGKHNDLDNVGYTARHHTFFEMLGNFSFGDYFKDRAIELAWTLITKEFGLKPDKLLVTVYADDDEAAGLWKKIAGFSDDKIIRIGTSDNFWQMGDTGPCGPCSEIFIDQGPALQGGPPGSPDEDGDRFLEFWNLVFMQYEQLEPGVRNPLPRPSIDTGMGLERMAAILQGVHSNYDTDLFRALIDAVAHAVSRAPEPATMASYRVIADHLRASSFLVADGVLPGNEGRGYVLRRIMRRAMRHAEILGAREPTMFRLVPTLVREMGQAYPELMRAESLIAETLKLEETRFRRTLERGLSILDAESRDLREGDKLSGETAFTLYDTYGFPLDLTQDALKARGIGVDTDAFAAAMQRQKQAAREAWKGSGEAATETVWFGLRERVGATEFLGYETENAEGIVTALLRDGAEVTTLAAGQTGLVLVNQTPFYGESGGQVGDTGLILAPGVRARVTDTQKKLGDVFVHHVTVEEGTLSLDQPVELKVDNVRRKAIRANHSATHLLHEALRQVLGDHVAQKGSLVSPERLRFDISHPKPIEADELARVEDIANAVLLQNAPVVTKLMAVDDAIASGARALFGEKYGDEVRVVSMGLPVDGEAAQPRARNFSVELCGGTHAARTGDIGAITIVAESAVGAGVRRIEALTADAARRHRAEEARTLAALAGILKAPVSEAPDRLTALMEDRRRLERELAETRRKLAMGGEGGPGSGAQQTEIGGVAFRRSVIEGLDMRDLKPIVDEEKKRLGSGIVAVVGIGPDGKAGLVVGVTDDLTARYDAVGLVRAGAGALGGKGGGGRRDMAQAGGPNGAGAEAALDAVAQALTEAA
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDGD_CHESB
Sequence: MEPQDLKTVLGAGLLSFPVTPFGPDGGFNEAVYREHVGWLASFEAAALFAAGGTGEFFSLAPDEIPAIVRAAKAAAGNTPIISGCGHGTEVAISIAKAAEKAGADGILLLPHYLIDAPQAGLYNHIKRVCDSIGIGVMVYNRDNSILQADTLKRLCDVCPNLVGFKDGSGELGLVRQISATMGDRLTYLGGMPTAELFAEAYLAAGFTTYSSAVFNFVPELAVRFYKALRAGRRAECETLLKDFFYPFMAIRNRSKGYAVAAIKAGVRLRGYDAGPVRSPLVDLTSEEMDMMASLMASVDR
What are the official names of this protein?
Probable 5-dehydro-4-deoxyglucarate dehydratase, 5-keto-4-deoxy-glucarate dehydratase, KDGDH.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
Protein: GLMM_STRP7
Sequence: MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKVFVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASHNPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKYEGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGSTHPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLAQNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMDYNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAIKAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: KV240_HUMAN
Sequence: MRLPAQLLGLLMLWVPGSSEDIVMTQTPLSLPVTPGEPASISCRSSQSLLDSDDGNTYLDWYLQKPGQSPQLLIYTLSYRASGVPDRFSGSGSGTDFTLKISRVEAEDVGVYYCMQRIEFP
What is the function of this protein?
V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170).
What are the official names of this protein?
Immunoglobulin kappa variable 2-40.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: Y1231_ACTP2
Sequence: MPSFDIVSEITMHEVRNAVENANRVLSTRYDFRGVEAVIELNEKNESVKLTTESDFQLEQLIEILIGSCVKRGIEHNSLDIPSEAEHHGKLYSKEVKLKQGIETEMAKKITKLIKDSKIKVQTQIQGEQVRVTGKSRDDLQAAIQLVKGAELGQPFQFNNFRD
What are the official names of this protein?
UPF0234 protein APL_1231.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: ISCR_ALISL
Sequence: MKLTSKGRYAVTAMLDVALHAQEGPVPLADISERQGISLSYLEQLFSKLRKAGLVASVRGPGGGYRLGLKPDEIAVGMVISAVDESVDATKCHGKEGCQGGTRCLTHTLWRDLSSRISSFLDGISLGELMVDNEVQQVSDRQNIDAALNNGLVTNSKLTNSVGVNVRF
What is the function of this protein?
Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.
What are the official names of this protein?
HTH-type transcriptional regulator IscR.
Protein: LPXC_SALDC
Sequence: MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDLNPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIPIMDGSAAPFVYLLLDAGIDELNCAKKFVRIKETVRVEDGDKWAEFRPYNGFTLDFTIDFNHPAIDSSSQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVVDDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVLAKQEAWEFVTFQDDAELPLAFKAPSTVLA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: EEIG2_HUMAN
Sequence: MMKKKKFKFKVDFELEELSSVPFVNGVLFCKMRLLDGGSFTAESSREVVQANCVRWRKKFSFMCKMSASAATGILDPCIYRVSVRKELKGGKAYAKLGFADLNLAEFAGSGNTTRRCLLEGYDTKNTRQDNSILKVLISMQLMSGDPCFKTPPSTSMSIPIAGESESLQEDRKGGETLKVHLGIADLSAKSASVPDELGACGHSRTSSYASQQSKVSGYSTCHSRSSSFSELCHRRNTSVGSTSTGVESILEPCDEIEQKIAEPNLDTADKEDTASEKLSRCPVKQDSVESQLKRVDDTRVDADDIVEKILQSQDFSLDSSAEEEGLRLFVGPGGSTTFGSHHLPNRVGSGAYEQVVIKR
What are the official names of this protein?
EEIG family member 2, EEIG2.
What is the protein family that this protein belongs to?
Belongs to the EEIG family.
Protein: RL6_CLOBB
Sequence: MSRVGRLPIAVPAGITVTVTPDNVVTVKGPKGELVKTMHKDINIAVENNEVIVTRPSDQKAHRALHGLTRALINNMVIGVNEGYQKTLELVGVGYRAQLQGKKLVMNLGYSHPVEIEPIEGITFETPAATKVIVKGIDKEKVGAAAADIRKWRLPEPYKGKGIKFENEVIRRKEGKTGKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: EMC4_SALSA
Sequence: MASPGGQGGGAVSTRGAGARRMKWALELSLGNARGRGDRQSNQGDVMYPIGYSDKPVPDTSIQETDKNLVEKRCWDVALGPLKQIPMNLFIMYMSGNTISIFPIMMVCMMAWRPIQALMSMSATFKLLENSNQQWLQGLVYSVGNLLGSALAIYKCQSMGLLPTHSSDWLAFIEPPQRMEIMGGGMVL
What is the function of this protein?
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.  Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues.  Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices.  It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes.  By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins like the G protein-coupled receptors.  By regulating the insertion of various proteins in membranes, it is indirectly involved in many cellular processes.
What are the official names of this protein?
ER membrane protein complex subunit 4, Transmembrane protein 85.
What is the protein family that this protein belongs to?
Belongs to the EMC4 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Could also be a single-pass transmembrane protein with cytosolic N-terminus and lumenal C-terminus.
Protein: SPT3_SCHPO
Sequence: MTETGRTSKYRVEIQQMMFILGEVQDPLPETTQLVEELIRGQVMEMLIQANELALRRGSRSITVEDLFFLIRHDRAKVNRLKTYLSWKEVRKKAKEQDANPADTKDLFEEVDSKTRSMNAVAMPWEVKNMFTEPVPETEEFEEDNDTMEMAYATRQRLKMADERTKKMTREEYVHWSECRQASFTYRKGKRFREWCGMSILTDTRPDNDIVDILGFLTFEIVATLTEEALAVKDRMDRIQNSSGSGGSHAAHHPKNCSLFDGLTEGRTPLQVSHVLEAFRRLQIPDKTHTAMRSFHGGLVKSRVYLI
What is the function of this protein?
Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA.  SAGA is involved in RNA polymerase II-dependent transcriptional regulation.  At the promoters, SAGA is required for recruitment of the basal transcription machinery.  It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction (spt3, spt8 and spt20) and promoter selectivity, interaction with transcription activators (gcn5, ada2, ada3 and tra1), and chromatin modification through histone acetylation (gcn5) and deubiquitination (ubp8).  SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac).  SAGA interacts with DNA via upstream activating sequences (UASs).  Spt3 is required for recruitment of TATA-binding protein (TBP) to SAGA-dependent promoters.  During SAGA-mediated transcriptional inhibition, spt3 and spt8 prevent binding of TBP to the TATA box (By similarity).  SPT factors 3, 7 and 8 are required for the initiation of Ty transcription from the delta promoter.  Spt3 regulates Ty1 as well as the mating factor genes.
What are the official names of this protein?
SAGA complex subunit spt3.
What is the protein family that this protein belongs to?
Belongs to the SPT3 family.
Protein: SYY_ESCF3
Sequence: MASSNLIKQLQERGLVAQVTDEEALAERLAQGPIALYCGFDPTADSLHLGHLVPLLCLKRFQQAGHKPVALVGGATGLIGDPSFKAAERKLNTEETVQEWVDKIRKQVAPFLDFDCGENSAIAANNYDWFGNMNVLTFLRDIGKHFSVNQMINKEAVKQRLNREDQGISFTEFSYNLLQGYDFACLNKLYGVSLQIGGSDQWGNITSGIDLTRRLHQNQVFGLTVPLITKADGTKFGKTEGGAVWLDPKKTSPYKFYQFWINTADADVYRFLKFFTFMSIEEINALEEEDKNSGKAPRAQYVLAEQVTRLVHGEEGLQAAKRITECLFSGSLSALSEADFEQLAQDGVPMVEMEKGADLMQALVDSELQPSRGQARKTIASNAVTINGEKQSDPEYFFKEEDRLFGRFTLLRRGKKNYCLICWK
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.