PharMolix/UniProtQA huggingface dataset:
Protein: NU188_DROME
Sequence: MPAVEKSVITDWKRLWPMVSGIHYETPQDTVREELMNVASELQAGVLQFKPKNASSLELGTLLKEKKQEKLLPFTERLQDLLDLESAQCWEILCYYLTQEYRGSASLLTQLISTETNMAKLHEDIRHYYSLERMVVLKIVKNLIVFHQVPNHPYHREYRAVVEKITIPRLRDSYLDQLESLICEVPPRKLMAGECFHSAERLVAWSERNAREINEVLHILLVLAEHLPMGLEQIKRIFAACKQHSFGKMQSYLDDSQPYHQEIIRSLSYSELMLVLKCLDFEKPEKHSDLIEKLIEDLQVDIASMYHRPEHGPLLLAWMLLRLRGTNDADDASSLLRCRQLGKRAVDLKCFVQLHLIARHSMYADDSMLSRIVRRTIYNQVGYLCDLFDGDGSCARYEGIYELLCELVSWPHLAKDFCSREDDGPCSLYKTLLENFPLELTHLSKLALSLTKAGQGNYVKSQLEALPILALRYDESQHKLREVDTNEFELLASVQPFQQIDFTIPAGTSCTAIQHPSGCFMHFRFPVNYFDALHHEINCLLRETGHLHGDFESSERIRNVEAGLRFLESAVKLSQSISGISAEMVHPTEMCVDLLHTFKSVQYPPVGLLSSCLNVCTALLPLVDEEIFSRISNLHILPTVSPGSHYDFKMYANANGVGFESRFLGSVIDNVEKKRERYEFLLSYIGFLRAYSNLKRNRQIQMEIPGLIFLLKDVFPHLHTWHFSSQVERNKIYFEILSFICDILDLFNTAKESNCKQRELLVKVCVYSLLNLENGLILLRFVGVGNAYVQYTMELETNWMQQQPHGLMMLVRLSMRILMQLLRLKEEVYGNSETLSPLEALIYTQPKQRDTLRIIPTVCSYMSNIFDRWLPILSCRLLKRIALQFNMSLLACLDMEADQIRLTFMQKLPDELESDSIKIAILELVDACIAKQPGVTEAFFKVNYALDKRSRSFFSKDCVPNIGESIVTYMRDFLDALQVDPLTIQQALPAKIMTIFHSMWKHNLQMLVDDLVKDKQFWKKLCSPLFSELQPNLRIYTQLLNIISIEVYTGNGNNAALLDVMNKFFEQKNFGPWLNYVFNMPKVPAVKNLSSSDHLPDWICCLQAFKDLIVILLKKQPKFVTIPESQFKLMAQKCLVVLVDRSNYLEDMRPFIILAELYVFILLEFKHAYTDSLEEEQTLMDLLLQLMNRICACYEDQHVRAKEACLAIVTKCTHLYTDLLIRDSSIALRFLNSVVGIICSELQHMENSVSLEKSQGLNNSDSSDSKTSTNSLILCLNLLKAVATIFHNDGPGNWDLPFVSVRLFQRLVRCVSRTLPLFSKQVLSVQLLDVLIVFAKGHCSVEFLHCDVGEYLWLKLLPPRELLQSKHEFTKTTAADAEGWTVEQWWPVYARGIELVTIIYEKHKKCFLEDAFQFVGIHAVFLEDALLLSKQSLEPSAMYLIKAAVNLVASLTEHHKEWKQDSDLSLANLMRAVQSLLCHTSSLFHQQKNLKCLLAGRRSQLEILRSTEALIVDDELISACNDLTDIIISCVKALLRFSPDLMELLCCSAYEPSKHSILLDVKFGAPKLNEENLTLTFGIVLNLVNIYVKALNMQNHGFSEVPLNSLPNVEHSGDNDDPEVCVGNQTNRTFSKPLSNVSISTGTCPASELLSNMDGQLCLLALEHLLMLVASQAICIIRSPNLETLWKQIVRRDISNELLIFNEFVRRKVILDYKENRSPWLRRKHGLCKLKCVDPVRSSSSSSRSSEIVRRSNTNNELRVNVVRRLHLQQQQRTPPPQNFDMSSDLSPIAAAQGAAMTTSLDGRKRLYPAQQAGDAFLEDELAAIELQYFPPPTEPGYCELSQVQVVEEDYLQLMSALFNVMPHCD
What is the function of this protein?
Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope.  Required for proper protein transport into the nucleus.
What are the official names of this protein?
Nucleoporin Nup188, Nucleoporin 188kDa.
What is the protein family that this protein belongs to?
Belongs to the Nup188 family.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex.
Protein: RL30E_METTH
Sequence: MDIDRGIRVAVDTGNVILGSKRTIQSLKLGKGKLVVMASNIPEDLKEDIEYYAKLSEIPVYTHEGTSVELGSVCGKPFTVGALLIQDPGDSTILEMVG
What are the official names of this protein?
50S ribosomal protein L30e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL30 family.
Protein: MTGA_CYTH3
Sequence: MYIEIIFSCKQLMKKAKIILLTCCIYFFVYTFQIVLVFKFVNPVVTPLMIVRVAEGVFSKEYVGIRKTWKPIKEISPNMVCAVIASEDHHFLEHNGFDWEAIRAARAYNERHKNGIKRGASTISQQTAKNVFLFPSRSWIRKGFEAYFTFLIELLWSKERIMEMYLNEIEMGKGIYGIEAAAQKYYHIPAKKLSQQQAASIAAILPLPLKRNPLKPGKNTASRVLWIRSQMSSVEKPTWILKSK
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: MUTS_DESPS
Sequence: MPKLKITPMMQQYFKLKEQHPHTILFYRMGDFYEMFFEDAITASKILGITLTSRNKKSDSAQIPMCGIPYHALQGYLAKMVEAGKRVAICEQVEDPSTAQGIVKREVVQIVTPGVVTDNQLLDAKSNNFVTAISRGKNNRYGLSFLDITTGEFIVADFAGSDGEADILDQLTRLTPTELLVSEEELEDFAETIDLATTLIPGLCITPRPHHLFDFDQSHEKLLEHFAVISLDGFGCETLVEGQIAAAILLDYIEETQKSAIHHIEKLSRLELDAILQIDDSSRRNLELTQTIVGGNRSGSLLSVLDLTTTPMGARFLKQAILFPLQDRARILRRLNAVGYFFNNSEARHQIRELLDQVYDIERLNSRITLGSANGRDMLAMKQSLARLPEMLTELRKCDTDELIEIEQTLDTLEDLHQLLDKSIHPDPPTNIREGNLIREGYNAELDEIIVLLRDGKKLILDLEAKERERTGIAKLKVSYNRVFGYFIEVSRAQSSRVPEHYIRKQTLVNAERFITPELKEFETKVLGAEDRRLELEYQLFATVRNELASHSSRFLATAHQLALLDFYASAAEVSQQYNYHRPEIRDDGSLEIREGRHPVIERSLPAGKFVPNDVYLDQAENEILVITGPNMAGKSTVLRQTALIVLMAQMGYYVPADSARIGVVDRIFTRVGAMDDLRRGQSTFMVEMSETANILNNATPRSLVILDEIGRGTSTYDGLSIAWAVTEHLVQKDGIGVKTMFATHYHELTDLARRYARIQNYSIAVREWQKSVIFLHKLIKGGTSRSYGIQVAALAGVPAQVVERAHEILHSIESGDFLAGEKVGGQPQKELSEHKPHQPSLFAPPTDEIRTKIREMDLDELTPRQALDALYALKEMTV
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: YME2_CANAL
Sequence: MIIRTLRSQLRLPKPVYISPPCRYYSTDLEKLKKESDTTESDNSASATGVIDKTHNEVLLYYDHIYPFTTSRNVVKQYLSRFSLPWSTAYDDEKLKQKVWDLSSPLETTAKITEFVPLRRDCGAFVKFKYPPEVPATKFIEEIRENVEKNEQERVNSNILTKLYHQIWRNVPKVYSVKGTPWIEDLRRFPSPKLSVKFEGDPLTEEELYVLFRRYGLINEIEPGATEAFIYFHSTRAAISAKHCITGMVLNGGKTTLHIQFVAIKRSNFLVSLISNHTKIAIPVLIALLATFAVLIFDPIREWFIEYKILHNRKSFDQFKESRWFKYLYIPYRTITGWVYSSYDYIDSQIQEVTGSSCSEEDDSSNGSNIVDGQSVRDLKNESNMFWIERYEKSKQLQLWIMENANTFIIVKGPQGSGKEEFVLEHSLGSDERLNKKVLVLECDQLGKARSDNNLINTTASQLGYFPVFTWTNTVSRFVDLGVQGLTGQKSGLSESKETQIKNMFSLATQAIRKITTNEYNKYVKSVERRNKRLKDDEKIEVLKEEQFLQQHPEAKPIIVLNKYSRRADVSSNDFIPPLVADWASGLVQNNTAHVIFLTADVGSLQLLNDALPNQVFKDISLSDASMSSSRQYVCDVLKVKDTSTLDECLEPLGGRMLDLQSFIRRIKSGESPQQAINEMISQAAELINTFFLNSHHKFGAGDSNWDPSQVWLIMKLLSECDTINYSELVKSPLFKVSKETLEILTTLEKYDLISLKRDKGVLDKISTGRPLFKAAFANIISDLRIWKLYETEYIGRLISLEAAKIQKLEEELEKIYKIGKVDGRIDYVSQKIEASNKKILDLEKQAADVASYTGKPDGKSFLGIKF
What is the function of this protein?
Plays a role in maintaining the mitochondrial genome and in controlling the mtDNA escape.  Involved in the regulation of mtDNA nucleotide structure and number.  May have a dispensable role in early maturation of pre-rRNA (By similarity).
What are the official names of this protein?
Mitochondrial escape protein 2.
What is the protein family that this protein belongs to?
Belongs to the YME2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: YDIB_SALHS
Sequence: MDVTAKYELIGLMAYPIRHSLSPEMQNKALEKAGLPYTYMAFEVDNTTFASAIEGLKALKMRGTGVSMPNKQLACEYVDELTPAAKLVGAINTIVNDDGYLRGYNTDGTGHIRAIKESGFDIRGKTMVLLGAGGAATAIGAQAAIEGIKEIKLFNRKDDFFEKAVAFAKRVNENTDCVVTVTDLADQHAFTEALASADILTNGTKVGMKPLENESLIGDVSLLRPELLVTECVYNPHMTKLLQQAQQAGCKTIDGYGMLLWQGAEQFELWTGKAFPLDYVKQVMGFTA
What is the function of this protein?
The actual biological function of YdiB remains unclear, nor is it known whether 3-dehydroshikimate or quinate represents the natural substrate.  Catalyzes the reversible NAD-dependent reduction of both 3-dehydroshikimate (DHSA) and 3-dehydroquinate to yield shikimate (SA) and quinate, respectively.  It can use both NAD or NADP for catalysis, however it has higher catalytic efficiency with NAD.
What are the official names of this protein?
Quinate/shikimate dehydrogenase, NAD-dependent shikimate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: CSGC_ECOK1
Sequence: MNALLLLAALSSQITFNTTQQGDMYTIIPEVTLTQSCLCRVQILSLREGSSGQSQTKQEKTLSLPANQPIALTKLSLNISPDDRVKIVVTVSDGQSLHLSQQWPPSSEKS
What is the function of this protein?
Plays a role in the extracellular assembly of CsgA into thin aggregative fimbriae (Tafi) fibers.  Assembly may also require CsgE.  Tafi are thought to be assembled via an extracellular nucleation-precipitation (ENP) pathway, and possibly also via an intracellular non-CsgC-dependent pathway (By similarity).
What are the official names of this protein?
Curli assembly protein CsgC.
What is the protein family that this protein belongs to?
Belongs to the CsgC/AgfC family.
What are the subcellular locations of this protein?
Periplasm.
Protein: CYSI_PROMH
Sequence: MKSQTQAPLVVEGKLSDSERMKKESNFLRGTISDDLQNGLTGGFEGDNFLLIRFHGMYQQDDRDIRAERAQQLLEPRHAMMLRCRLPGGVITPKQWLSIDKFASENTLYGSIRITNRQTFQFHGILKGHVKPAHQMLASTGLDALATANDVNRNVLCTSNPEQSSLHQEAYEWAKKLSEHLLPRTHAYAEIWLDKEKVATTDEEPILGETYLPRKFKTSVVIPPYNDVDLHANDMNFIAIAENGHLVGFNVLVGGGLAMTHGDKKTFPRLASEFGYIPIDKTLAVAEAIVTTQRDWGNRTERKNAKTKYTLERVGIETFKQEVERRSGVMFDMIRPYQFTHRGDQIGWLKGVDNKWYLTLFIESGRLIDKPNAPLKTGVAEIAKVHLGDFRLTANQNLIVAGVPEAQKEQIEAIARQYGLINDEVTPLRKHAMACVSFPTCPLAMAEAERFLPAFTDTLDNIMAKYGVSDEHIVVRVTGCPNGCGRAMLAEVGLVGKAPDRYNLHLGGNRMGTRIPRMYRENISSQEIIEILDTLIGQWAISRELNEGFGDFLIRTDVIKPVVNSAIDFYEVQEVI
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: EIF3E_CULQU
Sequence: MSKFDLTAKNCQYLDRHLTFPLLEFLLQKNIYDQTSLLKFILETVSKTNMVDYTMDIRERLNMGNELPEELTKRRSNVLVKLKELQTEVAPLMKCMEELKNPDTMKDSKSIVHALQQEFDFKYDIIRSAQKLAKYLYECGNYRDSISYLYICLLVMEPTDKNYLNVLWGKLAAEILTLNWPTALEDLTRLRDFIDNHNFSPIEVLQQRTWLIHWSVLVFFNHAKGRDLIIEMFLYKQLYLNAIQTMCPHILRYLATAVIINRGRRNALKDLIKIIQQESYTYKDPITEFLECLYVNFDFEGARMKLHECQTVIINDFFIIGCLQEFIENARLMIFETFCRIHQCITIGMLADKLNMEPDEAECWIVNLIRNARLDAKIDSKLGHVVMGTQPLSPYQQLVEKIDSLSVRSEALTVLVERKQKAKTQESGEGNWKYY
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit E, eIF3e, Eukaryotic translation initiation factor 3 subunit 6.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit E family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAUR_CUPNH
Sequence: MSNHSNAAAVRAFRILEILSAADGPLSLAAIVQAIELPKQTVHRILKQLESTWLVSRTAGNRHYECSSRVRQLAVNVLMQAGPAAARHAILQQLVDKIGETCNLTMLSGDDVVYLDRVETQWPLRMHLQPGSRVPLHCTASGKLLLAFLPSAQRQRLVASLPLRAHSAHTITNAEALHAELAETRQRRLGVNNQENLEGMIAVAVPVMRNRSRACAAIAVQVPMARMTMDQLMGFVPDLRLAADEMVKTFCE
What is the function of this protein?
May regulate transcription of the sauSTU operon.
What are the official names of this protein?
Probable transcriptional regulator SauR.
Protein: PUR5_LISMO
Sequence: MAENAYSKAGVDVEAGYQVVERIKKHVARTERIGAMGALGSFGGMFDLSSLNLKEPVLVSGTDGVGTKLLLAIEADKHDTIGIDCVAMCVNDILAQGAEPLFFLDYIATGKTDPVKMEQIVKGVADGCEQAGAALIGGETAEMPDMYGADDYDLAGFTVGAVEKQKLITEGAVQAGDTLIGIPSSGIHSNGYSLVRKIFFKDNEFTLDAEISELDVPLVEELLKPTRIYVKPVLEVLKEVTVHGITHVTGGGFVENLPRMLTNDLAVKVELGSWPMLPIFDVVKKYGQLNEMEMYEIFNMGIGMVLAVAKSDVEKTLEVLVQNGEAAYVIGEVTTRESNAVIFAGGKKG
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METAA_STRZP
Sequence: MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLMPQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDGMIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQMDSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVGVSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLCWSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RARD_PSEAE
Sequence: MRISGQGVLLSLAASVLFVTLPGYVHLLEPLDSLQVVAHRVVWSIPMVFLLVVATRQWPTLRAAWCRLFAEPWLLACFPLTAAMMLLQWGIFIWAPLAGKTLELSLGYFLLPLAMVLVGRVFYGERLTPLQAIAVACALAGVLHEFWLTRAFSWVSLVTALGYPPYFMLRRRMGVDALSGFVFEMLFLLPLALAALYWLGDESQAFREAPRLWLLLPMLGLISALAFGAMMASSRLLPMGLFGILSYVEPVLLFLVAVLFLGEAFRPEQLWTYAPIWLAVLLTGWDSARLLRKQARRGI
What are the official names of this protein?
Chloramphenicol-sensitive protein RarD.
What is the protein family that this protein belongs to?
Belongs to the EamA transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HTPX_BACSU
Sequence: MAKRIFLFILTNILVLTTIGIVLSVLSSVTGVGTYFTADGGIDPMALLVFSLVVGFVGSFTSLAISRWMAKTMMGVRVLNPKKHSLSYEEQQLVDRVHRLSRSAGLTKMPEVGIYRSPEVNAFATGPSKRRSLVAVSSGLLEQMDDAAVEGVLAHEVAHITNGDMVTMTLLQGIVNTFVVFLSRIAAWIASRFVKEDLAPIVHFIAMIIFQIVFSILGSLVVFAYSRHREFHADRGGADLAGKDKMIHALRTLKSYSSRILEDDQTAVQTLKINGKKRSSLFSTHPDLDERIRRLEAK
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RSMH_HELMO
Sequence: MEFHHIPVLLEEVLEALQPRPDGLYLDGTVGGGGHSAAILEKTAGQGRLIGLDQDPRALAAARIKLEKFADQVTLVRSNFRQLGSVVEELGQKGKIDGILLDIGVSSHQLDEAERGFTYRAEAPLDMRMNPDGAVTAAQILNEYPEGEIFRILWEYGEERWSKRIAQFIVNRRTEQPLASTTDLVDVIRAAIPAAARQEGGHPAKRTFQALRIAVNDELGALQEALPAALDALAPSGRLAVISFHSLEDRIVKNFFAEQAKGCTCPPDMPVCGCGKKARLKIITRKPITGSEEELKINPRSQSAKLRVAQKI
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAT_SHIBS
Sequence: MSSRVLTPDVVGIDALVHDHQTVLAKAEGGVVAVFANNAPAFYAVTPARLAELLALEEKLARPGSDVALDDQLYQEPQAAPVAVPMGKFAMYPDWQPDADFIRLAALWGVALREPVTTEELASFIAYWQAEGKVFHHVQWQQKLARSLQIGRASNGGLPKRDVNTVSEPDSQIPPGFRG
What is the function of this protein?
This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response.  It forms, in concert with DnaB protein and other prepriming proteins DnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'.
What are the official names of this protein?
Primosomal protein 1, Primosomal protein I.
What is the protein family that this protein belongs to?
Belongs to the DnaT family.
Protein: HEM1_SHEFN
Sequence: MSLVIIGINHKTATVDLREKVAFSPDRIHDAMKSLASRTRTGEAVIVSTCNRTELYCNNAEKEDIIEWLEDYHGLDHNDLMPCIYAYEEQVAVKHLMRVASGLDSLVLGEPQILGQVKQAFVKAKEAGTIALTIDRLFQNTFSVAKKVRTDTEIGAAAVSVAFAAVSMAKHIFSSLSTTKVLLIGAGETIELVAKHLKDNGVASMVVANRTIERAQAMCEEFNATAITLEQIPDFLPKADIVISSTASPLPILGKGMVEKALKQRRHQPMLLVDIAVPRDIEAEVGELDDAFLYTVDDLHSIIEQNMASRKEAAEQAELITEDQSHIFMEWIRSLESVDSIREYRSQSLAIKDELVERALNKLSQGSDSEQVILELANRLTNRLIHSPTQALTSASRQGDLNTLGQLRSALGLDKN
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: MURD_DESPS
Sequence: MLKKNPYIDAHTTFAIIGLGVSGKAALRYALGFGAHLLVSDRRDEEALLAQLVALAGDVVVDYEAGGHTFQFLSQADVIFVSPGFADGELLARLRRAGVQVLGELALAAPVLDRPVVAITGTNGKTTVTSLVGDLLRASGKRVFVGGNIGVPLLDLLSSGDEVDVIVLEVSSFQLELAGDFSPHIALLLNLSPDHLDRHGDLAGYRAAKMHLFQKQGMTDIAIVSGDDPLCLLSDGCGEASRYLFGFSAASDISVAAGHFEFDFAGQREIYSLRDSALDNRTGWLNAAPAAFIARSLACAKADIERGIAAFTLDAHRMEPVASIAGVQYYNDSKATNTGAVISALQQLVRVILIAGGRDKGDNYRLLREAVAGHVRTLICIGEATPLLVAALEDVVQVYRATSLAEAVSLAASFAEEGDSVLLSPACASFDMFANYQDRGEQFRRQVLQLQDVGSK
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_NOCFA
Sequence: MANYTAADVKRLRELTGSGMMDCKNALAETDGDFDKAVELLRIKGAKDVGKRAERTTAEGLVAAKDGVMIEINSETDFVAKNDEFQALANQIVTAAAAAKTADLDSLKALDLGDGRTADAALQELAAKIGEKLELRRVVSLDGPVATYLHKRASDLPPAVGVLVEYQGAGDAAAEAARAAAMQVAALKAKYVTRDEVPADIVENERRIAEQTAREEGKPEAALPKITEGRVNGFFKDVVLLEQPSVTDNKKTVKQQLDEAGVTVTRFARFEVGQA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DLH1_CANAX
Sequence: MSVEDSIISIDSLQDQGINAGDINKLKSAGICSITSVLSTTRRNLTKIKGLSEIKVEKIKEAAGKIKKYGFLPATIVAESRTKVFHITTGSKQFDEILGGGIQSMSITEVFGEFRCGKTQLCHTLCVAAQLPTDMGGGEGRVAYIDTEGTFRPDRIRSIAERYGVDADICLENISYARALNSEHQIELVEQLGNELAEGTFRLLIVDSIMACFRVDYSGRGELNERQQKLNQHLSNLTRVAEDYNIAVFLTNQVQSDPGASALFAAADGRKPVGGHVLAHASATRILLRKGRGEERVAKLQDSPNMPEKECVYVIGEGGIKDTD
What is the function of this protein?
Required for meiotic recombination, synaptonemal complex formation and cell cycle progression.
What are the official names of this protein?
Meiotic recombination protein DLH1, DMC1 homolog.
What is the protein family that this protein belongs to?
Belongs to the RecA family. DMC1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: MYPR_MACFA
Sequence: MGLLECCARCLVGAPFASLVATGLCFFGVALFCGCGHEALTGTEKLIETYFSKNYQDYEYLINVIHAFQYVIYGTASFFFLYGALLLAEGFYTTGAVRQIFGDYKTTICGKGLSATVTGGQKGRGSRGQHQAHSLERVRHCLGKWLGHPDKFVGITYALTVVWLLVFACSAVPVYIYFNTWTTCQSIAFPSKTSASIGSLCADARMYGVLPWNAFPGKVCGSNLLSICKTAEFQMTFHLFIAAFVGAAATLISLLTFMIAATYNFAVLKLMGRGTKF
What is the function of this protein?
This is the major myelin protein from the central nervous system.  It plays an important role in the formation or maintenance of the multilamellar structure of myelin (By similarity).
What are the official names of this protein?
Myelin proteolipid protein, PLP, Lipophilin.
What is the protein family that this protein belongs to?
Belongs to the myelin proteolipid protein family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Myelin membrane. Note=Colocalizes with SIRT2 in internodal regions, at paranodal axoglial junction and Schmidt-Lanterman incisures of myelin sheat.
Protein: RL25_CLOPE
Sequence: MMENLQVNQREKKTRHSSRQCRRKGLVPGVIYGKGINNFLFEIGELELNHALSVTGEHGLLSINSQEGSLNTLIKEVQRDPVTRRVLHIDLEKVEGNEEIETAVPINYVGEEYINKLDAVLQKNLDSIKVKCSPSNIPKGVNLNVGRAKPGDQFKIADVEFGNEITVVDDLNSIVASVSYDQKIITQEVVDQEVAENRAKKES
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: CLPC_STAA8
Sequence: MLFGRLTERAQRVLAHAQEEAIRLNHSNIGTEHLLLGLMKEPEGIAAKVLESFNITEDKVIEEVEKLIGHGQDHVGTLHYTPRAKKVIELSMDEARKLHHNFVGTEHILLGLIRENEGVAARVFANLDLNITKARAQVVKALGNPEMSNKNAQASKSNNTPTLDSLARDLTVIAKDGTLDPVIGRDKEITRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQAIVNNEVPETLKDKRVMSLDMGTVVAGTKYRGEFEERLKKVMEEIQQAGNVILFIDELHTLVGAGGAEGAIDASNILKPALARGELQCIGATTLDEYRKNIEKDAALERRFQPVQVDEPSVVDTVAILKGLRDRYEAHHRINISDEAIEAAVKLSNRYVSDRFLPDKAIDLIDEASSKVRLKSHTTPNNLKEIEQEIEKVKNEKDAAVHAQEFENAANLRDKQTKLEKQYEEAKNEWKNAQNGMSTSLSEEDIAEVIAGWTGIPLTKINETESEKLLSLEDTLHERVIGQKDAVNSISKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALAESMFGDDDAMIRVDMSEFMEKHAVSRLVGAPPGYVGHDDGGQLTEKVRRKPYSVILFDEIEKAHPDVFNILLQVLDDGHLTDTKGRTVDFRNTIIIMTSNVGAQELQDQRFAGFGGSSDGQDYETIRKTMLKELKNSFRPEFLNRVDDIIVFHKLTKEELKEIVTMMVNKLTNRLSEQNINIIVTDKAKDKIAEEGYDPEYGARPLIRAIQKTIEDNLSELILDGNQIEGKKVTVDHDGKEFKYDIAEQTSETKTPSQA
What is the function of this protein?
Required for growth at high temperatures, probably by acting as a chaperone during heat shock and targeting heat-denatured proteins for degradation by ClpP.  Required for biofilm formation.  May act as a chaperone regulating CtsR activity.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpC.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family. ClpC subfamily.
Protein: END4_PARUW
Sequence: MSHSNLLLGAHTSAAGGVYRALLEGKKIGATTIQFFTSNQKQWKGRQFTTNDIELWQSTLKETNLTHLMSHDSYLINLGCPNQENLLKSRQAFQEEVIRCTQLGINYLNFHPGASLGEDVQKCLDSIVESLLLVRPFIQGNLRLLLEATAGQGTSVGHKFEQLAYIINGVKDELPIGVCIDTCHIFVAGYDIRTSSAWDFTLKGFDRIIGLPYLYAFHINDSSKDLGSRVDRHQPLGEGKIGWESFEFLMKDSRTRHLPKYLETPGGVDLWEKEIQKLKEFA
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: IF2A_HYPBU
Sequence: MPIQRKELPDVGELVVATVKEVYDYGAYLTLDEYGGLEAYLPWSEVASRWVRSIHDVVKPGQKIVVKVIRVNKRKKQVDVSLKRVTDSERRRKMMEWKRAQKAERILELVAQKLGKSLEEAYEAVGKKLEDYYGELMAAFEEVVIRGEQALREAGVPEEWVQPLLEEIKRHVEVKRVKIAGVLTVRSLAGDGIERVKKVLLTVKDAIENSSPDIKVKLYTVGAPRYRLELEAYDYKTLEKALAKALEEGEETAKSLGVEFSFTREKQ
What is the function of this protein?
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
What are the official names of this protein?
Translation initiation factor 2 subunit alpha, aIF2-alpha, eIF-2-alpha.
What is the protein family that this protein belongs to?
Belongs to the eIF-2-alpha family.
Protein: PELO_THEPD
Sequence: MRVLGLNQERGEVELVVEVLEDLYYLFLLVRKGDVVYGWTTRQLRIERATGEERGERIPVYLGVEVEKVSYAKFSEKLRFTGRVVEAPEEVYAKGSFHTIQVGVGDRVKIVKKSGIDGFTRNILEKAASKIRRVLLISVGDEEVAVGYLSPVGVEVRAVVGYSPVGRGKESSLDERYREPIASIVQRIFESGRAEHVDEVVVAVNERLAEVVSRVLGELGVKARVVKVSEGGEAGIYELLRGGQSRELLSSVRLPLELAEVERVLQELFSGKGKAVAGLENVEKVAEWGIVKTLIVSDALLFGEESRERVLKVLGEVFSRNGKIFIVPEESEAGRKLKPFGGALAELYYSLE
What is the function of this protein?
May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA.  May play a role in the release non-functional ribosomes and degradation of damaged mRNAs.  Has endoribonuclease activity.
What are the official names of this protein?
Protein pelota homolog.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR18_CHAVU
Sequence: MKKKPIQKQRSRRRLPPIKSGEKIDYKNLDLLRRFLSEQGKILSKRVNRLTSKQQRTMTIAIKRARILALIPFLNNEN
What are the official names of this protein?
30S ribosomal protein S18, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: AGUA_YERP3
Sequence: MLQQQALPGTPRQDGFFMPAEWAPQDAVWMLWPYRQDNWRGKAIPAQQTFAKVAEAISRATPVFMGVPAEFMAQAKATMPANVTLVEMASDDAWMRDTGPTMVINGAAERRAVDWQFNAWGGLNGGLYADWQQDEKVAVQVSDFLKNAHYSAPLILEGGSIHTDGEGTLLTTAECLLNPNRNPHLNQAQIEQLLCDYLGVTHFIWLQDGVYNDETDGHIDNMCCFVRPGEVALHWTDDQQDPQYARSVAAFEVLSNTVDAKGRKLKIWKLPAPGPLYNTEEETFDVLTSDAVPRTAGERLAGSYVNFLISNQQIIFPLLDSRTDGQANDLLQQMFPGYAIVGVPAREILLGGGNIHCITQQIPAA
What are the official names of this protein?
Putative agmatine deiminase, Agmatine iminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the agmatine deiminase family.