PharMolix/UniProtQA huggingface dataset:
Protein: RUVC_ACIBC
Sequence: MPLIIGIDPGSRLTGYGIIEKDGSKLRFVDAGTIRTETQEMPERLKRIFAGVERIVKFHGPTEAAVEQVFMAQNPDSALKLGQARGAAIAALVNLDLQVAEYTARQIKQSVVGYGAADKEQVQMMVMRLLNLTIKPQADAADALAAAICHAHASGSMSKLTVLNALGGMARGRSRSSSRRR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: RF1_MYCTA
Sequence: MTQPVQTIDVLLAEHAELELALADPALHSNPAEARRVGRRFARLAPIVATHRKLTSARDDLETARELVASDESFAAEVAALEARVGELDAQLTDMLAPRDPHDADDIVLEVKSGEGGEESALFAADLARMYIRYAERHGWAVTVLDETTSDLGGYKDATLAIASKADTPDGVWSRMKFEGGVHRVQRVPVTESQGRVHTSAAGVLVYPEPEEVGQVQIDESDLRIDVFRSSGKGGQGVNTTDSAVRITHLPTGIVVTCQNERSQLQNKTRALQVLAARLQAMAEEQALADASADRASQIRTVDRSERIRTYNFPENRITDHRIGYKSHNLDQVLDGDLDALFDALSAADKQSRLRQS
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YB56A_YEAST
Sequence: MRHQYYQPQPMYYQPQPQPIYIQQGPPPPRNDCCCCCNCGDCCSAIANVLCCLCLIDLCCSCAGGM
What are the official names of this protein?
Uncharacterized protein YBR056W-A.
Protein: SBP_CAEBR
Sequence: MGVCISHEYSKPTAQETEIQQQFSNFSKVDERPPMAVEHQMYDYRQAYEEQDDELFAIICCPHSIGFDRDKIALIDLDPTSDTYCTIISEIRLTSNGDEPGRMNWAKSAESLIEMDKLIRKNIIVPCMNSGKIYVIGFDKNKFYMEKSKNIFKLQEIRSDELFRKDVSCPYAVRSLPLKGAPVHVSTMGDRYGHGKGDFVLIDRKTWEIRKKSDPTFSSFGGDFSLQPRHNLLISSEWGHPRLFRDGFQPSELENVSESFGSCLHVWQISPPKLLQSIGLDSFDGSLVISVKFLHNTDCNHAFAISAIGSSIFHLHMNTLSREWQADRVAHVPSLKVENWVSDEMPALLTDMIISMDDRWLYVCGFLHGIVWRFDIQDPFRVSLHGKINLGGVFDSSPEVRIKTSNAMEDRWWLPPETRSLPRGTKFRGGPALMQLSKDGSRLYVCNSFYKAWDGQFYPELISDGGQMVRVDIVDNEMRLNKKFLVDMKDQPNGPFVIRDIKFLDGDCTSDSFL
What are the official names of this protein?
Putative selenium-binding protein.
What is the protein family that this protein belongs to?
Belongs to the selenium-binding protein family.
Protein: BORG3_MOUSE
Sequence: MPVMKQLGPAQPKKRLDRGALSISAPLGDFRHTLHVGRGGDAFGDTSFLSRHGGGPPPEPGAPPVVAPHSVAPPAAPQPPVAVPSPADPLLSFHLDLGPSMLDAVLGVMDAERSETTATKPDGDAHPRVQHPKTRCCSNADLQLDDVIGL
What is the function of this protein?
Probably involved in the organization of the actin cytoskeleton.  May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes.  Induces pseudopodia formation in fibroblasts.  Inhibits MAPK8 independently of CDC42 binding.  Controls septin organization and this effect is negatively regulated by CDC42.
What are the official names of this protein?
Cdc42 effector protein 5, Binder of Rho GTPases 3.
What is the protein family that this protein belongs to?
Belongs to the BORG/CEP family.
What are the subcellular locations of this protein?
Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton.
Protein: GSP1_LOTGI
Sequence: MVIKTSLTVLILGVLIAEVFCAGHSQCNRRENPVNPFSYYETVNGKETLRMCPAAQIFNKTSCHCNAVEVVPGSGMNFRSGQQNFQWSSSGSSGGGMGASGMGANGMVASGIGASGIGTSGMGASNTNAMMNAFLGGSKAGSGNIATSGTSSGKFKVTLPFNPLILKWTKSSNGGWGAETGSSGGMNSQSSGSQSGSWGSSSGSWGGSSGSMGSSGNWLNDLQFMGNMRPQGINFPAPIMNIKVSGTGGSSQGVLRAARPHP
What are the official names of this protein?
Glycine and serine-rich protein 1, Uncharacterized shell protein 1, LUSP-1.
What are the subcellular locations of this protein?
Secreted.
Protein: MD2BP_HUMAN
Sequence: MAAPEAEVLSSAAVPDLEWYEKSEETHASQIELLETSSTQEPLNASEAFCPRDCMVPVVFPGPVSQEGCCQFTCELLKHIMYQRQQLPLPYEQLKHFYRKPSPQAEEMLKKKPRATTEVSSRKCQQALAELESVLSHLEDFFARTLVPRVLILLGGNALSPKEFYELDLSLLAPYSVDQSLSTAACLRRLFRAIFMADAFSELQAPPLMGTVVMAQGHRNCGEDWFRPKLNYRVPSRGHKLTVTLSCGRPSIRTTAWEDYIWFQAPVTFKGFRE
What is the function of this protein?
May function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex.
What are the official names of this protein?
MAD2L1-binding protein, Caught by MAD2 protein, p31(comet).
What is the protein family that this protein belongs to?
Belongs to the MAD2L1BP family.
Protein: GATA_KINRD
Sequence: MSGSASELVRWDAARLSEALRAGEVSAEEVTRAHLDRIDAVDGPTSGAGETGVHAFLHVDHEGALARARQIDADRAAGAELGPLAGVPIGVKDVLTTKGLPTTAGSRMLQGWVPPYDATVVRELHAAGLVVLGKTNMDEFAMGSTTEHSAYGVTRNPWDPTRIPGGSGGGSAAALAAFEAPLTIGSDTGGSIRQPAAVTGTVGVKPTYGAVSRYGLIALASSLDQAGPCARTVLDTALLHAVIAGHDPYDSTSIPAAVPDVVGAARLGATGDLAGVRVGVVRELSGEGYEPGVLARFEESLTELRAAGAEVVELSLPNIVHALAAYYLILPSEASSNLAKFDGMRYGLRVVPEGEHVTAEAVMRATRAAGFGDEAKRRIILGTYALSAGYYDAYYGSAQKVRTLVQRDFDAAFGSVDVLVSPTAPTVAYRLGEKLDDPLAMYAGDVATIPANLAGIPGMSLPCGLSEGLPVGLQVLAPQQADDRLYRVGAALEARLNDKWGGPLLAQVPTWQGASA
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: ROMO1_DANRE
Sequence: MPVSVGSYGQQAQPSCFDRVKMGFMMGFAVGMAAGAMFGTFSCLRIGMRGRELMGGVGKTMMQSGGTFGTFMAIGMGIRC
What is the function of this protein?
Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation.  May play a role in inducing oxidative DNA damage and replicative senescence.  May play a role in the coordination of mitochondrial morphology and cell proliferation (By similarity).
What are the official names of this protein?
Reactive oxygen species modulator 1, ROS modulator 1, Protein MGR2 homolog.
What is the protein family that this protein belongs to?
Belongs to the MGR2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: DPYD_ARATH
Sequence: MASMSFALNRFSGLSSKTTLSADFDPSSRRSFLPPTRVGLKISSAAESEPDLSVTVNGLKMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVIAKTVSLDASKVINVTPRYARLRTGSNGSAKTDVIGWQNIELISDRPLETMLKEFERLKKEYPDRILIASVMEEYNKTAWEELIDRVEQTGVDALEINFSCPHGMPERRMGAAVGQDCALLDEVCGWINAKATVPVWAKMTPNITDITEPARVSLKSGCEGIAAINTIMSVMGIDMKTLRPEPCVEGYSTPGGYSYKAVRPIALAKVMNIAKMMKSEFSEDRSLSGIGGVETGYDAAEFILLGSNTVQVCTGVMMHGYGHVKTLCAELKDFMKQHNFSTIEEFRGHSLQYFTTHTDLVKRQKEAVEQRKAEKRGLKSDKDWTGDGFVKETESMVSN
What is the function of this protein?
Involved in pyrimidine base degradation.  Catalyzes the reduction of uracil to 5,6-dihydrouracil (DHU) by using NADH as a specific cosubstrate and the reduction of thymine to 5,6-dihydrothymine (DHT).  Involved in the recycling of nitrogen from nucleobases to general nitrogen metabolism.
What are the official names of this protein?
Dihydropyrimidine dehydrogenase (NADP(+)), chloroplastic, DHPDH, DPD, Dihydroorotate dehydrogenase-like protein, Dihydrothymine dehydrogenase, Dihydrouracil dehydrogenase, Protein PYRIMIDINE 1.
What is the protein family that this protein belongs to?
Belongs to the dihydropyrimidine dehydrogenase family.
Protein: MSRB_SALTI
Sequence: MANQPSAEELKKKLSEMQFYVTQDRGTEPPFTGRLLHNKRDGVYHCLVCDTPLFHSHTKYDSGCGWPSFYQPVSEEAIRYIDDFSHGMQRVEIRCGNCDAHLGHVFPDGPQPTGERYCVNSASLAFSDEKNGDQLKG
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: OTOP_DROME
Sequence: MDSSPDLSLKLRRGSSDSRDNFYMDFAQGIDSDIEEVDNTANNQEAGEVPPPPLPTVSLAEEVLLLVAPPPPPPSLLGQPLPTLTETDDIPPTPTPPPQQKDDEGDDEDEREEPVPEQDQGAPAAPSPPGSPINSVLELELIPPPPLSPMDDAGLRTDDDGEGEETDDAEEVAAIPPPHEMLDIESNPDEEEEEEEQEQASQEDTPKEEDEEEDDDKSTPPPPLPPLPSNFSYVQGHNLGQVTPPLTKSPSNSPSPPVTPPPCPELNISRMVSPPAQHISQIPPLTPSDESEGEAESQPNSPPLRLDAEQPPPDMDQPEPEDQPPEPENEPEPEPEPEPEPEPVSGAREDYSRSLDNEDESTTITTPPSNGYSASSIIAPPPEHFAELDEDRGFIPPPPLEQEPEEEVEEEEEEEEEELTKETDEISVDRESLQDQGGDSISSPRPASILTGSISTSVGGGAGGSPKPESRGPSRSGSQRSQLRSGSQQGSIAESRGGSRIGSRTGSVASAQAAGVLSPQASLKSQTSIRSQGQAGVRSPAGSIKSGSQRMQSPQAGEGAPAMPSPPLMRSPPPELARQMHSPPRITTPPRVCSPPLVSSPPKLAESAAAAVGVAATVKEQIGSSSSTAEPLEPSKPEPLKPPIATVSYQDEQKPSPPPTAAAAPAVTTTAATTAVTSQPRSHFTSSHHHYHLPHQFQHPHHQNHHTHSVRVPTPTVPSSYAPPPPPDSGSSSSPVDRRRLFMAGVAPPIAAGAGSLMAMPAEPAVAISPGRVSARSGSQHHVTIDESSLPSHKGNIQETPGPSGLIIGGGDGDGDRDIGGGGGPDSSDPPSSPGGSSSQPALSGSQADGQLALMYHSHQLTNYPVLPAIKRTHRPSFVYPPMPRVKAGDALATLFSALYGKLLVVMGIAFPMAEVISTYIPPSFYEVYYLYLYIGSMIFLLFMYATLIWGRPKLPVPIASPSKSATKASGTDSMDESDTDSNSVHHRLPPPIPVRRPSLLSPLGRRDAHYGSFYLRMGAVAFGIGSMIYSGLEFGQYFELNPDTKCHNVLLALTPATRMAFIFIQMYFIFLNNEQIKVYRYKIIARFGLMHMIGTNLAVWLNVLIQETKHEILTFYNPENRTLRISHRIPGHSRGHAIIQHDPTAHLRVPRGLKGPYQIFECRRTNIIGTLVQDASPFLFPCTIEYSLICAAILYVMWRSISRPQTPTPQRPDMISSPMKRSPHHYSVDCARAHKGLFVGILILVLTIISLIIFFVLISRPEFVAMAVTEVTICELLIYGTATIATLVGMIQIRHLQYDAYRSFSLDDILLVGAQTGSFLYNIFTVIAGHFTLRSDDMLVPINALASIVQTACQTMFILDASRRQAVSPEHLRKKPGREIVTFMLVVNLAMWAISTLEKSRAESHPIQLNFYGLWAWTIITHVSMPLAIFYRFHSTVCLCEIWKRAYKLKPTYMXEFARSRIQSIAQQQQFCEDLKTNLSYCYCSTTLAGGELETVEEVDSGESNSAEDAGAGAGSGGSRGSGGGAGAAEAGEAGEEGQQGGDSSCGLKAPIRALSPQSLNTEKAFCPVYVINGE
What is the function of this protein?
Proton-selective channel that specifically transports protons into cells.  Proton-selective channel activity is probably required in cell types that use changes in intracellular pH for cell signaling or to regulate biochemical or developmental processes.
What are the official names of this protein?
Proton channel OtopLc, Otopetrin-Lc, DmOtopLc.
What is the protein family that this protein belongs to?
Belongs to the otopetrin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VATB_HALS3
Sequence: MKEYQTITEVSGPLVYVETDEPIGYDEIVEIETPNGDVKRGQVLESSDGFVAIQVFEGTEGVGKDASVRFLGETLKMPVTEDLLGRVLDGSGNPIDGGPDIVPDDRVDIVGEAINPHAREYPEEFIQTGVSGIDGMNTLVRGQKLPIFSGSGLPHSDLALQIARQASVPEEEAETDDDEGSEFAVVFGAMGITAEEANEFMDDFERTGALERSVVFMNLADDPAVERTVTPRMALTTAEYLAFEKDYHVLVILTDMTNYCEALRQIGAAREEVPGRRGYPGYMYTDLAQLYERAGRIEGKEGSVTQIPILTMPGDDDTHPIPDLTGYITEGQIMMNRDLNSQGVTPPVNVLPSLSRLMDDGIGEGLTRADHGDVSDQLYAAYAEGEELRDLVNIVGREALSERDNRYLDFADRFEAEFIDQGFKTNRDIEETLDLGWELLSMFPKTELNRVDEDLIEDHYVEDVADEATAD
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The archaeal beta chain is a regulatory subunit.
What are the official names of this protein?
V-type ATP synthase beta chain, V-ATPase subunit B.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: PIGS_RAT
Sequence: MATAGAAATDLEVVRGKRAALFFAAVAILLGLPLWWKTTETYRAPLPYSEISGLNALQLRLMVPVTVVFTRDSVPLDDQEKLPFTVVHEREIPLKYKMKIKCRFQKAYRRALEHEEEALSLGSVHEAEALLAEPEKQAEGSLTVYVISEHSSLLPQDMMSYIGPERTAIVRGMIHREAFNIIGRRIIHVAQAMSLTEDVLAAALADHLPEDKWSSDKRRPLKSSLGYEITFSLLNPDPKSHDVHWDIEEGVQRYVQPFLNRLSAAGNFSVDSQILYYAMLGVNPRFDPASSSYSLAMHSLPHVINPVESRLGSSAASLYPVLNFLLYVPELAHSPLYIQDKDGAPVATNAFHSPRWGGIMVYNVDPKIYNASELPVRVEVDMAQVMEVFLAQLRLLFGIAQPQVPPKCLLSGPKSEGLMTWELDRLLWARSVENLATATTTLTSLAQLLGKISNIVIKDDVASEVYRAVAAVQKAAEALALGHLSSAFAASQEAVTSSERAFFDPSLLHLLYFPDDQKFAIYIPLFLPMAVPILLSLVKIFLETHKSWKKPEKID
What is the function of this protein?
Component of the GPI transamidase complex.  Essential for transfer of GPI to proteins, particularly for formation of carbonyl intermediates (By similarity).
What are the official names of this protein?
GPI transamidase component PIG-S, Phosphatidylinositol-glycan biosynthesis class S protein.
What is the protein family that this protein belongs to?
Belongs to the PIGS family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RL10_PROMM
Sequence: MGRTLESKQQIVEELKGLLGEAEMALVLDYQGLSIKEMSDLRTRLQASNGVCKVTKNTLMRHAINGNGAWSNLESLLTGTNAFVLIKGDVGGAVKAVQAFQKDTKKSETKGGLFEGKLLSQGEIKAIGDLPTKEVLMAQIAGSLNALATKVAVGINEVPSGLARALHQHAESGES
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: AROA_BACCN
Sequence: MANIRREKGLNGTIAIPGDKSISHRAVMFGAIAEGTTKVSNFLLGEDCLSTIACFRKLGVKIDQSGNDVTIYGKGLTGLQEPKEVLDVGNSGTTIRLMLGILANVPFHCTIIGDDSIGKRPMKRVTDPLREMNAQIDGREDGQYTPLSIRGGNIKGIHYDSPVASAQVKSAILLAGLKGEGVTTVTEPLQSRDHTERMLRAFGCTVEVTGQTVSLRGGQSLIGTEIEVPGDISSAAFFLVAGAIVPNSKIVLKNVGLNPTRTGIIDVLQKMGAILSVDHVRNEEFEPCGDITIETSKLQGIEIGGSLIPRLIDEIPIIALLATQATGTTVIKDAEELKVKETNRIDTVVQELKKLGVKIEATSDGMIIYGNQKLQGGIVDSHGDHRIGMMLAIASCIADGEVEIQRSDAVSVSYPNFFDQLASL
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB2_PSYIN
Sequence: MSTGKIIQVIGAVVDVEFPQETVPNIYSALIVTAKNLTMEVQQQIGGGVVRCIAMGASDGLSRGLDVTDTGKPITVPVGTATLGRIMNVLGEPIDMCGEIGATEHYGIHREAPTYEEQSASVATLEVGIKVIDLICPFSKGGKIGLFGGAGVGKTVNMMELINNIALKHSGLSVFAGVGERTREGNDFYFEMQEAGVVNVEKPELSKVAMVYGQMNEPPGNRLRVALTGLTMAERFRDEGKDVLLFIDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSIQAVYVPADDLTDPAPATTFAHLDATVVLNRSIASMGLYPAIDPLDSTSRQLDPLVVGQEHYDIARGVQGTLQRYKELKDIIAILGMDELSEDDKLVVSRARKIGNFLTQAYHVAEVFTGDPGMYVPLKDTLAGFKGLLAGDYDDLPEQAFLYIGAIEEAVEKAKKM
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta 2, ATP synthase F1 sector subunit beta 2, F-ATPase subunit beta 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS3_MYCA9
Sequence: MGQKINPHGFRLGITTDWKSRWYADKQYADYVKEDVAIRRLLATGLERAGIAKVEIERTRDRVRVDIHTARPGIVIGRRGTEADRIRADLEKLTGKQVQLNILEVKNPEAEAQLVAQGVAEQLSNRVAFRRAMRKAIQSAMRQPNVKGIRVQCSGRLGGAEMSRSEFYREGRVPLHTLRADIDYGLYEAKTTFGRIGVKVWIYKGDIVGGKRELAAAGVEAGRGAPDRPRRERPAGTRPRRSGSSGTTATSTEAGRAAAETPASDGASAPSAETTES
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: PL5_LUPLU
Sequence: SIFAFQDESPSAIAQAKLFK
What are the official names of this protein?
Protein PR-L5.
What is the protein family that this protein belongs to?
Belongs to the BetVI family.
Protein: COFE_METMA
Sequence: MKFEAIAVEKIPLIHEGDNLPSIICEKIGLQDRDIMIIASTIVAKAEGEIFRLEDITPGEEALEIAARTGKDPRFIQAVLSKSREVFVETPFMLVTTLAGHTCVNAGIDESNIENGFLLYPPENPDASALKIGKELEKLSGKKLSIIITDTNGRAFKIGQTGVAIGIYNIKPVKRWIGEKDLFGKVLEITEQAIADELAGAANLLMGEGAGGIPVVIIRGLDYYCEGDTSIKESYRPENMDVIKQGLRCLRNKK
What is the function of this protein?
Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives.
What are the official names of this protein?
Coenzyme F420:L-glutamate ligase, Coenzyme F420-0:L-glutamate ligase, Coenzyme F420-1:gamma-L-glutamate ligase.
What is the protein family that this protein belongs to?
Belongs to the CofE family.
Protein: SYD_LACLA
Sequence: MKRTNYAGNITEEYLNQTVTVKGWVAKRRNLGGLIFIDLRDREGIVQIVVNPETAAADVAEAADKARNEFVLEVTGKVVERASKNDKIKTGGIEIEATAIEILSTSKTTPFEIKDDVEVLDDTRLKYRYLDLRRPEMLKNITMRHATTRSIREYLDGAGFIDVETPFLNKSTPEGARDYLVPSRVNKGEFYALPQSPQLMKQLLMTAGLDRYYQIVKCFRDEDLRGDRQPEFTQVDLETSFLSEEEIQDLTEELIAKVMKDVKGIDVTLPFPRMKYDDAMNFYGSDKPDTRFELLLTDLSALAKTIDFKVFQEAEVVKAIVVKDAADKYSRKSIDKLTEQAKQNGAKGLAWVKFEKGEFAGGVSKFLAESTDSFVNELKLTDNDLVLFVADSLDVANSALGALRLTIGKQQGLIDFRQFNFLWVIDWPMFEWSDEEERYMSAHHPFTLPTKETQAFLSADGHSKDSDLKKVRAHAYDIVLNGYELGGGSLRINTRQLQEEMLSALGFKLEDANEQFGFLLEALDYGFPPHGGLALGLDRFVMLLAGKDNIREVIAFPKNNKASDPMTQAPSIVAEKQLEELSIKLANKDQ
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS3_JANSC
Sequence: MTQFDPATLRYDVNGLIPCIAQQEGTGEVLMMAWMNADSVARTLESGRVTYWSRSRQAFWVKGETSGHVQELVDLRVDCDRDCLLAVVRQTGPACHTNRRVCFYTSVTSGEEVELMAPE
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRA_HELPY
Sequence: MDKIIIQGARENNLKNIFLEIPKNQFVVFTGLSGSGKSTLAFDTLYAEGQRRYLESLSSYARQFLDKVGKPNVDKIEGLTPAIAIDQKTTSKNPRSTVGTITEIYDYLRLLFARVGEQFCPTCLEPISSMSTSDIISQICHLEENSKIIILAPIIKDKKGSFNDKLESLRLKGYVRAFVDGVMVRLDEEIHLHKTKKHTIEAVVDRVVVNNENASRIASAIEKALKESYGELEVEILQDNAPSIRKHYSEHKACFKCKMSFEELEPLSFSFNSPKGACESCLGLGTKFSLDISKILDPNTPLNQGAIKVIFGYNRSYYAQMFEGFCEYNGIDSALCFNELNKEQQDALLYGNGTEISFHFKNSPLKRPWKGIIQIAYDMFKEQKDLSDYMSEKTCSSCEGHRLKASSLSVQVAGLKMADFLTKPIEEVYHFFNDPTHFSYLNEQEKKIAEPILKEILERVFFLYDVGLGYLTLGRDARTISGGESQRIRIASQIGSGLTGVLYVLDEPSIGLHEKDTLKLINTLRNLQKKGNTLIVVEHDKETIKHADFVVDIGPKAGRHGGEVVFSGSVKELLQNNHSTALYLNGTKKIERPKFELPKEKHFLEIKNVNINNIKNLSVQIPLKQLVCITGVSGSGKSSLILQTLLPTAQTLLNHAKKTQSLNGVEIVGLEHLDKVIYLDQAPIGKTPRSNPATYTGVMDEIRILFAEQKEAKILGYSASRFSFNVKGGRCEKCQGDGDIKIEMHFLPDVLVQCDSCKGAKYNPQTLEIKVKGKSIADVLNMSVEEAYEFFAKFPKIAVKLKTLMDVGLGYITLGQNATTLSGGEAQRIKLAKELSKKDTGKTLYILDEPTTGLHFEDVNHLLQVLHSLVALGNSMLVIEHNLDIIKNADYIIDMGPDGGDKGGKVIASGTPLEVAQNCEKTQSYTGKFLALELK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrA is an ATPase and a DNA-binding protein.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
What are the official names of this protein?
UvrABC system protein A, UvrA protein, Excinuclease ABC subunit A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. UvrA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPFR4_XENRU
Sequence: GFGSFLGKALKAALKIGANALGGSPQQ
What is the function of this protein?
Antimicrobial peptide.
What are the official names of this protein?
Caerulein precursor fragment R4, CPF-R4.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TIG_RICCN
Sequence: MGITILKNEGLDFHARISTPLSEIDDDIQKELLDLTKKVKIAGFRAGKVPVSIVKKKYGTSVRNDIIERRINNSVNHVIKEHNLNIIGRPKIEELQNESDKALEFTVKIELLPKITIPDLKKISLDRPKLEVNSKDVEEQLEKLAALTKNYTKESKAKIKDGDQVTIDAIGYIKEKAFEDGKLNDFKVIIGSNALIPGFEKQLIGSKTGSKVDVNVTFPENYHAKDLAGKDARFVVQIKAVHTAEPTVIDDEFAKKFQSNSLEELRTHFTKQIENESEEAINTIMKMNLFDKLEKLLDFDVPESLLEQEKNILKSGTDKNEQDESLLKDKSSKEITAYYNKLALRRVRIGLLLAEYAKSKNLQLEPDDLRKVIMQQARNFPGQENMIFDFYKNNPRAIEGLKGPALEDKAVQYIFNHEIKLKEKKYTKEELEKYLEAEEQRITLI
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: UBID_SHISS
Sequence: MDAMKYNDLRDFLTLLEQQGELKRITLPVDPHLEITEIADRTLRAGGPALLFENPKGYSMPVLCNLFGTPKRVAMGMGQEDVSALREVGKLLAFLKEPEPPKGFRDLFDKLPQFKQVLNMPTKRLRGAPCQQKIVSGDDVDLNRIPIMTCWPEDAAPLITWGLTVTRGPHKERQNLGIYRQQLIGKNKLIMRWLSHRGGALDYQEWCAAHPGERFPVSVALGADPATILGAVTPVPDTLSEYAFAGLLRGTKTEVVKCISNDLEVPASAEIVLEGYIEQGETAPEGPYGDHTGYYNEVDSFPVFTVTHITQREDAIYHSTYTGRPPDEPAVLGVALNEVFVPILQKQFPEIVDFYLPPEGCSYRLAVVTIKKQYAGHAKRVMMGVWSFLRQFMYTKFVIVCDDDVNARDWNDVIWAITTRMDPARDTVLVENTPIDYLDFASPVSGLGSKMGLDATNKWPGETQREWGRPIKKDPDVVAHIDAIWDELAIFNNGKSA
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TX10A_MANRB
Sequence: MRLSYISLTIAIIFVMAIVHAPETEAKAYPEADAVAEAIAVGEADAVGVADPGFKSMLAKAALKILKAVAPAAAAAIADKIG
What is the function of this protein?
Induces paralysis after injection into blowflies (L. caesar) (PubMed:32182430).  In most cases is not lethal 24 hours after injection, but paralysis is irreversible (PubMed:32182430).  May have antimicrobial properties, like most ant linear peptides (By similarity).
What are the official names of this protein?
U10-myrmicitoxin-Mri1a, U10-MYRTX-Mri1a.
What is the protein family that this protein belongs to?
Belongs to the formicidae venom precursor-01 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MAOX_CHICK
Sequence: MKRGYEVVRDPHLNK
What is the function of this protein?
Catalyzes the oxidative decarboxylation of (S)-malate in the presence of NADP (+) and divalent metal ions, and decarboxylation of oxaloacetate.
What are the official names of this protein?
NADP-dependent malic enzyme, NADP-ME.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_GEOSL
Sequence: MARIAGIDLPRNKRIEIALTYIFGIGRTTAQRILAETGVSADTRTDNLAESEVAKIRDYIDKNLKVEGDLRRDVSMDIKRLMDLGCYRGLRHRKGLPVRGQRTKTNARTRKGPARTVAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.