PharMolix/UniProtQA huggingface dataset:
Protein: RNC_MYXXD
Sequence: MMRLSGADKMSPSERVQLLESRLGLSFSRMETALEALTHKTYVNETRDKELKDNQRLEFLGDSVVNLAVSHRLMARCPGLPEGDLTKMRARVVNEDGLARVARTIPLGDLLLLGRGELMSGGREKNSVLADALEAVFGAVFLTSGLDAAVTLVDRYFADLLDEVSSGQGRLDYKTLLQEMAHERLKLQPRYRVVSESGPEHSKVFEVELMLGETAFARATGRSKKEAEQSAAQATLEKLREDAACPTSPPPGTPRHDTPA
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_RUEPO
Sequence: MSDPKKLFIKTYGCQMNVYDSERMAEALGGQGYVETQSAEDADMILLNTCHIREKAAEKVYSELGRFKGLKAAKPDLKIGVAGCVAQAEGEEIMRRQPLVDLVVGPQSYHRLPELEAKTRAGEKALDTDFPEEDKFEKLKGRPKAKRGPTAFLTVQEGCDKFCAFCVVPYTRGAEVSRPADRILREANELVERGVREITLLGQNVNAYHGAGPNGDMTLAGLIWELDKIDGLERIRFTTSHPNDMADDLIEAHGTCAKLMPYLHLPVQAGSDKILKRMNRSHTAESYLRLIERIRAARPDIVMSGDFIVGFPEETEADFQDTLDLVEQVRYGYAYSFKYSTRPGTPAAERAQVDPAEADDRLQRLQAVITRHQREIQDGMVGREVSVLFEKPGRQPGQMVGKSEYLHAVHVQDPGLEAGQIARVRIVASGANSLAGELA
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PARP2_MAIZE
Sequence: MSARLRVADVRAELQRRGLDVSGTKPALVRRLDAAICEAEKAVVAAAPTSVANGYDVAVDGKRNCGNNKRKRSGDGGEEGNGDTCTDVTKLEGMSYRELQGLAKARGVAANGGKKDVIQRLLSATAGPAAVADGGPLGAKEVIKGGDEEVEVKKEKMVTATKKGAAVLDQHIPDHIKVNYHVLQVGDEIYDATLNQTNVGDNNNKFYIIQVLESDAGGSFMVYNRWGRVGVRGQDKLHGPSPTRDQAIYEFEGKFHNKTNNHWSDRKNFKCYAKKYTWLEMDYGETEKEIEKGSITDQIKETKLETRIAQFISLICNISMMKQRMVEIGYNAEKLPLGKLRKATILKGYHVLKRISDVISKADRRHLEQLTGEFYTVIPHDFGFRKMREFIIDTPQKLKAKLEMVEALGEIEIATKLLEDDSSDQDDPLYARYKQLHCDFTPLEADSDEYSMIKSYLRNTHGKTHSGYTVDIVQIFKVSRHGETERFQKFASTRNRMLLWHGSRLSNWAGILSQGLRIAPPEAPVTGYMFGKGVYFADMFSKSANYCYASEACRSGVLLLCEVALGDMNELLNADYDANNLPKGKLRSKGVGQTAPNMVESKVADDGVVVPLGEPKQEPSKRGGLLYNEYIVYNVDQIRMRYVLHVNFNFKRR
What is the function of this protein?
Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism.  This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks (By similarity).
What are the official names of this protein?
Poly [ADP-ribose] polymerase 2, PARP-2, NAD(+) ADP-ribosyltransferase 2, ADPRT-2, Poly[ADP-ribose] synthase 2, Protein ADP-ribosyltransferase PARP2.
What is the protein family that this protein belongs to?
Belongs to the ARTD/PARP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HUTH_HALH5
Sequence: MTNLKLLDGRSLSLHDLHRIIYEGETVGASDESMEKVKQSRKAVEQIVADEKIIYGITTGFGKFSDIFIDPDDVENLQHNLIYSHACGVGSPFPETVSRTMLVLRANALLKGFSGVRPLVIERLLALVNANIHPVIPQQGSLGASGDLAPLSHLALVLLGEGEVFYKGTKTKASFALKEEEIEPITLTAKEGLALINGTQAMTAMGVIAYLEAEKLAFQSEIIASLTMEGLRGIIDAFDEQIHFARGYVEQVDVARRMESYLQDSQLTTRQGELRVQDAYSLRCIPQVHGATWQTLRYVKEKLEIEMNAATDNPLIFDNGQKVISGGNFHGQQIALAMDFLGIAMAELANISERRIERLVNPQLNDLPPFLSAAPGVQSGVMILQYCAASLVSENKTLAHPASVDSIPSSANQEDHVSMGTIGSRHAYQIIQNVRNVLAIELICAMQAVDIRGREKMASFTKKILEKGREHVPYIDQDRMFAKDIERAAKWLKDGSWDFTKMREKERTNHY
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
Protein: GSA_IDILO
Sequence: MSRSEELYTKAQISIPGGVNSPVRAFNGVGGSPIFFESAEGAYMIDADGKRYIDYVGSWGPMILGHNHPAVLEATLQAAKRGLSFGTPTEVEITMAETIRKIVPSIEKVRMVNSGTEATMTAIRLARGYTGRDKILKFEGNYHGHADSLLVKAGSGALTLGVPNSPGIPEDFAKHTLTATYNDIESVKQIFAEMGDEIACIIVEPVAGNMNCIPPVDGFLEGLRSICDDHGSVLIFDEVMTGFRVAPGGAQDRYKIKPDLTTLGKVIGGGMPVGAFGGKKEVMDYIAPVGPVYQAGTLSGNPVAMAAGLAALQQLSTPGLYDQLYQRVDTLLDGLQERADRAGVPMTTNRAGSMFGFFFTEEPEVTTYAQATQCNMEHFKTFYHAMLEQGVYLAPSAFEGGFMSAAHSEEDIQNTLNAAEKAFAKLV
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK34_NEOYE
Sequence: MTKRTLQGSKRKKIRVSGFRARMKTPCGRSILNSRRRKGRKKIMVS
What are the official names of this protein?
50S ribosomal protein L34, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DCA11_BOVIN
Sequence: MGSRNSSSAGTGSGDPSEGLPRRGAGLRRSEEEEEEDEDVDLAQVLAYLLRRGQVRLVQGGGAANLQLIQALSDSEEEHDSAWDGRLGDRYNPPVDATPDTRELECSEIKTQVELATGRLGLRRAARELSFPQMLHQRERGLCHQGSFSLGERSRVMSHFLPNDLGFTDTYSQKAFCGIYSKDGQIFMSACQDQTIRLYDCRYGRFRKFKSIKARDVGWSVLDVAFTPDGNHFLYSSWSDYIHICNIYGEGDTHTALDLRPDERRFAVFSIAVSSDGREVLGGANDGCLYVFDREQNRRTLQIESHEDDVNAVAFADVSSQILFSGGDDAICKVWDRRTMREDDPKPVGALAGHQDGITFIDSKGDARYLISNSKDQTIKLWDIRRFSSREGMEASRQAATQQNWDYRWQQVPKKAWRKLKLPGDSSLMTYRGHGVLHTLIRCRFSPTHSTGQQFIYSGCSTGKVVVYDLLSGHVVKKLTTHKACVRDVSWHPFEEKIVSSSWDGNLRLWQYRQAEYFQDDMPESEEHPSTPAPMSHPSTAFSSPQ
What is the function of this protein?
May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
What are the official names of this protein?
DDB1- and CUL4-associated factor 11, WD repeat-containing protein 23.
Protein: COBD_CHLTE
Sequence: MTWLLMPAAFLLDLLLGDPQWFPHPVRLVGKLASGAERLFRGMRFLPLRLAGILTALVVIGTTVVTVLALVVAAFLLHPLAGVVVSVLLLYFAIAPRDLYNHGSAVRDALRAGDLELARQKVAMMVGRDTSMLDEEGVARAAVESVAENTSDGVTAPLFYGLLFGPAGAWLYKASNTLDSMFGYRNERYREFGWASARFDDFMNYLPSRLTVLAVAGAAFILRLDPAGVFRSVKLGATLHESPNAGYPEAAFAGALGVTLGGERSYGGVTKTVPTLGLREGALDATTITGAMRLMYVASVLFMACGALLLFILSKSLQS
What is the function of this protein?
Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
What are the official names of this protein?
Cobalamin biosynthesis protein CobD.
What is the protein family that this protein belongs to?
Belongs to the CobD/CbiB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NTPPA_RHOP2
Sequence: MLGRPKLVLASGSPRRLALLNQAGIEPDALRPADVDETPTKGELPRACANRLARAKAEAALKSVQLDDDLRGAFLLAADTVVAVGRRILPKAELVDEASQCLRLLSGRNHRVYTAVCLVTPKGSFRQRLIETKVRFKRLSEEDIDGYVASGEWRGKAGGYAVQGIAGSFVVKIVGSYTNIVGLPLYETTSLLGGEGYPIRFGWLNAS
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HGF_CANLF
Sequence: MWVTKLLPLLVLQQLLLHLLLLPVAVPRAEGQKKRRNTLHEFKKSAKTTLIKEDPLLKIKTKKMNTADQCANRCIRNKGLPFTCKAFVFDKARKRCLWFPFNSMTSGVKKEFGHEFDLYENKDYIRNCIIGKGGSYKGTVSITKSGIKCQPWNSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGPMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGKPRPWCYTLDPDTPWEYCAIKMCAHSTMNDTDVPMETTECIQGQGEGYRGTINTIWNGVPCQRWDSQYPHQHDITPENFKCKDLRENYCRNPDGAESPWCFTTDPNIRVGYCSQIPKCDVSSGQDCYRGNGKNYMGNLSKTRSGLTCSMWEKNMEDLHRHIFWEPDASKLNKNYCRNPDDDAHGPWCYTGNPLIPWDYCPIFRCEGDTTPTIVNLDHPVISCAKTKQLRVVNGIPTRTNVGWMVSLKYRNKHICGGSLIKESWILTARQCFPSRNRDLKDYEAWLGIHDVHGKGDEKRKQVLNVSQLVYGPEGSDLVLLKLARPAILDDFVSTIDLPNYGCTIPEKTTCSVYGWGYTGSINFDGLLRVAHLYIMGNEKCSQYHQGKVTLNESEICAGAENIVSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKIILTYKIQQS
What is the function of this protein?
Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types.  Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization (By similarity).
What are the official names of this protein?
Hepatocyte growth factor, Hepatopoietin-A, Scatter factor, SF.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Plasminogen subfamily.
Protein: CYL1_ARATH
Sequence: MTRSVSFPLFLFAVVLSLSSSLLADDPKPIRREVYEGGKIYDISHRYTPEIPAWESSEGLGKTFLRLAASMKNGSFANVSEMKLSVHSGTHVDAPGHFWDNYYDAGFDTDSLDLQVLNGPALLVDVPRDKNITAEVMESLHIQRGVRRVLFRTSNTDKRLMFKKEFDSSFAGFMTDGAKWLVENTDIKLIGLDYLSFAAFEESPATHRVILKGRDIIPVEALKLDGVEVGTYSLHCLPLRLVGAEGAPTRCILIK
What is the function of this protein?
Acts as a negative regulator of fumonisin B1- and pathogen-induced programmed cell death (PCD), and regulates pathogen-induced symptom development (PubMed:25862728).  May function redundantly with CYCLASE2 for normal plant growth, development and viability (Probable).
What are the official names of this protein?
Cyclase-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the Cyclase 1 superfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: CAPSD_AQRVA
Sequence: MPRTSRNVRATEVATTAIPPSNAATDTTVDTTVAPTIASADAAQHASNISSSQLGPAGVSDKVPSSVVTNDGDISVTPISENAAQLASSNQPASVIRNPVAAATISIVNPSSLRCQQCGAKFSSMTQLAEHVRTEHRTGAGSLVTSPAINQAIESWLLTWEDLRLLAPTIATDALNKYMGEAVAKAPLLIVEDEGLCTSFLASDTISIAGLQREIVGFTWFMETLQMIPALPEGAVNHPICHTGWASKDSVSRHLDVRLSPPTHGGCFSIHYRTVEGIRQGHAIQPSYFPCQRPHAGPQVRSVQSQDQQVYSVDSGPDPRSRGRYVRFFDNKELFAVAYPGREVLMEANRNALFLDESLPDRVGCIGRAQNVSGDVSAHIDTYELCDDLTLAIREMYHNMLFSMHLDPASVMEIVQDVSQQLVAASIPFAQTDTILCPWAASTPTLQLSQVLNLLNVANNTSAALPLIEAAATLIMGITPLRMEPRILSEAIKRVPETTTIVPSPTGELTRLLKPLGNDYSAIYRCIAGCLYSGLVQMFISADAYPDPTQSITSIPAIWKSLIVMLAAPMTTDPHAAVKAFMSMANLLAQPEPIIIPAPGMTQSTPAVQFSHPEVWPPGFVDPTTLDRNRTPLLHALATMIHAHWPQPGVIQYGRSRLGSANLFLPANQLTYPWPTQPLPRITVGPTYDSAMFRWIDSVFGFYINVVNSRYVATIVGDTTRRTLTGLMAALMQVKTMTPFYIERMCPTEVAVVGGVTVFPPFQVPITRLDPTQVITNVMVSPRGPPAPCRRSRRSHRYYAYAAPIPCQSIPLRLSLLCCVRQTEATLGPSYHYGSAITPMFLSEELFTRNQRAVIASEAFVCARSIIAQCVPDGFQVPRPLQDFNQYNASGSTAADLLKAVDDMFKTAFDIDGSLIEGIGLYGDPRVADLSVAYLRQNGAVERVHTAPDSSFLHEAMQVTSQVMVNEPNLWAIARGDIILAQNATHNNWDPLNPVGLPIFARGGPNVHVVGSRGMIIPQPGGLAPMIRDDAGNPQQIEGDWIYPISVLQVSVANFRDHVWPMIQAGRTRVRIEMGHFLYSIHYHEPFGQITEAPAIDTWLAGISPTGIPPFPLSAPIPQITIPITARRVYFGYCTMNNTGATFSTLGAAIQSAWGTDVTIQRNRWPALIDPNYIPGQSQLPARVQLYNPLRRYNYRYPSLKGMLYIPGVE
What is the function of this protein?
Self-assembles to form an icosahedral capsid with a pseudo T=2 symmetry, about 60 nm in diameter, and consisting of 120 VP3 subunits.  Displays NTPase, RNA 5'-triphosphatase (RTPase) and RNA helicase activities and probably participates in transcription of the viral genome.  Helicase activity might be involved in unwinding or reannealing dsRNA during RNA synthesis.  RTPase enzymatic activity represents the first step in RNA capping, which yields a 5'-diphosphorylated plus-strand RNA (By similarity).
What are the official names of this protein?
Major inner capsid protein VP3, ATP-dependent DNA helicase VP3.
What is the protein family that this protein belongs to?
Belongs to the reoviridae major inner capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: NAGK_SHIF8
Sequence: MYYGFDIGGTKIALGVFDSGRQLQWEKRVPTPRDSYDAFLDAVCELVAEADQRFGCKGSVGIGIPGMPETEDGKLYAANVPAASGKPLRADLSARLDRDVRLDNDANCFALSEAWDDEFTQYPLVMGLILGTGVGGGLVFNGKPITGKSYITGEFGHMRLPVDALTMMGLDFPLRRCGCGQHGCIENYLSGRGFAWLYQHYYHQPLQAPEIIALYDQGDEQARAHVERYLDLLAVSLGNILTIVDPDLVVIGGGLSNFPAITTQLADRLPCHLLPVARVPRIERARHGDAGGMRGAAFLHLTD
What is the function of this protein?
Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.
What are the official names of this protein?
N-acetyl-D-glucosamine kinase, GlcNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family. NagK subfamily.
Protein: CYSK_EMENI
Sequence: MFRQSVRRFATAALRSAAESPYNVRVSQAQGFVNGLTEAIGNTPLIRLKRLSEETGSNILAKAEFQNPGGSVKDRAALYVVKDAEERGLLKPGGTVVEGTAGNTGIGLAHVCRSKGYKLVIYMPNTQSQGKIDLLRLLGAEVYPVPAVAFDNPENYNHKARRHAESLDNAVWTNQFDNTANRRAHIETTGPEIWAQTGGKLDAFTCSTGTGGTLAGITYYLKQASGGRVKSFLADPPGSVLHSYIQSGGKLVERSGSSITEGIGQGRITDNLQPDVGTLDGSLNISDEKTIEMIYRCLDEEGLYLGASSALNVVAAKEVAEKLGKGSTVVTILADGAYRYADRLFSKSWLESKGLRNAIPKHLEKYIVLP
What is the function of this protein?
Catalyzes the conversion of O-succinyl-L-serine into cysteine, the last step in the cysteine biosynthesis pathway (By similarity).  Can also use O-acetyl-L-serine (PubMed:17482430).
What are the official names of this protein?
Cysteine synthase 1, CS 1, O-acetylserine (thiol)-lyase 1, OAS-TL 1, O-acetylserine sulfhydrylase 1, O-succinylserine sulfhydrylase.
What is the protein family that this protein belongs to?
Belongs to the cysteine synthase/cystathionine beta-synthase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: 3S31_PSETE
Sequence: MKTLLLTLVMVTIMCLDLGYTLTCYKGYHDTVVCKPHETICYEYFIPATHGNAILARGCGTSCPGGIRPVCCRTDLCNK
What is the function of this protein?
Binds with high affinity to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.  Compete with the binding of alpha-bungarotoxin on muscle AChR (from Torpedo) with an IC(50) of 0. 31 uM (SNTX1) and 3. 1 uM (SNTX5).  Is able of exerting muscle paralysis, spasms and increased respiration.
What are the official names of this protein?
Short neurotoxin 1/5, SNTX1, SNTX5, Alpha-neurotoxin 1/5.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type III alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PUP2_ARATH
Sequence: MKMKTVLVIINCIFLAIGNCGGPLMMRLYFQNGGERIWFPSFLQTVGCPLIFFPLLLSFLRRRRCLEEQETTPFFLMKPPLFIAAIVVGLLVGFDNYLYSYGLAYIPVSTASLIISAQLGFTALFAFFMVKQKFTPFTINAIVLLTGGAVVLALNSDSDKLANETHKEYVVGFIMTLGAALLYGFILPLVELSYKKSGQRITYTLALEFQMVLCFAATCVCLVGMLAAGDFKVKHALFIFKNRVIAGEARDFKLGESLYYVVIVFTAIIWQAFFVGAIGLIFCASSLVSGIMVSALLPVTVILAVICFQEKFQAGKGVALALSLWGSVSYFYGQVKSEEKTKAQDTQLSQLPVTDYVA
What is the function of this protein?
Mediates adenine transport.  May be involved in the uptake of cytokinin analogs.
What are the official names of this protein?
Purine permease 2, AtPUP2.
What is the protein family that this protein belongs to?
Belongs to the purine permeases (TC 2.A.7.14) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RRF_SHEHH
Sequence: MINEIKSDAQTRMDKCVESTKTQMAKVRTGRAHPSLLDTIQVPYYGSLTPLKQVASVSIGDARTLTVSVFDRTMIAAVEKAIMSSDLGLNPMSAGATIRIPLPALTEERRKDLIKVVRAEAENGRIAIRNVRRDANSNVKELEKEKECTEDDVRRSEDDVQKLTDAHIKLVDDVLAAKEKELMEF
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YL012_MIMIV
Sequence: MNTLKDIKIKNIKYYHTDDIIGLKLSQFKSCTNGRRLISNLNIDDNNYIFATNKSGKWIETDGKSRKFDKVLIKVSWIKENILDDDENDNENDNENDVENENDVENENDDENENDDDDDENDDDDDEIIMAPGIIKLNKNEKIRDDKNKIVDIEVRGTRDPRNCFFKASDVSKGFGMKNLSDTISRSSGYKLGIHYRYFYLQKNTDSIRKKNKIKKIKKIYLTYEGLLRVMFVSKNDRVSRFIMWATNTLFTAHLGTKEQKNMLSSKLMGITTDIVKEVFNKTSSTLPTLYLFTIGKVKDLRVTLDIGEEYDDECIVAKGGETIDLTRRIDEHTESYGKMPGAKLLLKSYNYIDPQYTSKAETDLFQVLKKMNYIFKHPKYKEIIIYTKKESDLITKEFSKIARDYTGHIKEISDKLKCFENQYNIMKLEYEKEIANKEKEIMQLEKENSDLKYQNEIIELKYKNKLLEKDRKIAKLEKNIKKSGLK
What are the official names of this protein?
Uncharacterized protein L12.
What is the protein family that this protein belongs to?
Belongs to the mimivirus L5 family.
Protein: CTNA3_MOUSE
Sequence: MSAETPITLNMDTQDLQIQTFTVEKLLEPLIIQVTTLVNCPQNPSNRKKGRSKRARVLLASVEEATWNLLDKGEMIAKEATVLKEELAAALQEVRKESKALKVSAERFTDDPCYLPKREAVVQAARALLAAVTRLLVLADMIDVMCLLQHVSSFQRTFESLKNVSNKSDLQRTYQKLGKELESLDYLAFKRQQDLKSPSQRDEIAGARATLKENSPLLHSICSACLEHSDVASLKASKDTVCEEIQNALDVISNASQGIQNAPAPPEPQAATLGSAFDELENLIVLNPLTVTEEDVRPSLEKRLEAIISGAALLADSSCTRDLHRERIIAECNAIRQALQDLLTEYMSNTGKTERSNTLNTAIVNMSKKTRDLRRQLRKAIIDHISDSFLDTTVPLLVLIEAAKNGRVKEIKDYAAIFHEHTGRLVEVANLACSMSTNEDGIKIVRIAANHLETLCPQIINAALALASRPKSQVVKNTMEMYKRTWEHYIHVLTEAVDDITSIDDFLAVSESHILEDVNKCIIALRDQDADNLDRAAGAIRGRAARVAHIVAGEMDSYEPGAYTEGVMRNVNFLTSTVIPEFVTQVNVALDALSKNSLTALDDNQFVDISKKIYDTIHDIRCSVMMIRTPEELEDVSDLEDDHEVRSHTSIQTEGKTDRAKMTQLPEAEKEKIAEQVADFKKVKSKLDAEIEIWDDTSNDIIVLAKKMCMIMMEMTDFTRGKGPLKHTTDVIYAAKMISESGSRMDVLARQIANQCPDPPCKQDLLAYLEQIKFYSHQLKICSQVKAEIQNLGGELIVSALDSVTSLIQAAKNLMNAVVQTVKMSYIASTKIIRIQSSAGPRHPVVMWRMKAPAKKPLIKREKPEETWAAVRRGSAKKKIHPVQVMSEFRGRQVY
What is the function of this protein?
May be involved in formation of stretch-resistant cell-cell adhesion complexes.
What are the official names of this protein?
Catenin alpha-3, Alpha T-catenin, Cadherin-associated protein.
What is the protein family that this protein belongs to?
Belongs to the vinculin/alpha-catenin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Localizes to intercalated disks of cardiomyocytes and in peritubular myoid cells of testis, and colocalizes with CTNNA1 and CTNNA2.
Protein: G6PI_SALPA
Sequence: MKNINPTQTSAWQALQKHYDEMKDVTIAELFANDSDRFAKFSATFDDLMLVDFSKNRITEETLAKLQDLAKETDLAGAIKSMFSGEKINRTEDRAVLHVALRNRSNTPIIVDGKDVMPEVNAVLEKMKTFSQAIISGQWKGYTGKAITDVVNIGIGGSDLGPFMVTEVLRPYKNHLTMHFVSNVDGTHIAEVLKKVNPETTLFLVASKTFTTQETMTNAHSARDWFLKTAGDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSAIGLSIILSVGFDNFVELLSGAHAMDKHFSTTPAEKNLPILLALIGIWYNNFFGAETEAILPYDQYMHRFAAYFQQGNMESNGKYVDRNGNAVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKMVPCDFIAPAITHNPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQGKDPAQLEHVVPFKVFEGNRPTNSILLREITPFSLGALIALYEHKIFTQGVILNIFTFDQWGVELGKQLANRILPELGDDKAISSHDSSTNGLINRYKAWRA
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VMA21_DROER
Sequence: MSTKNKKAAGGNGGAPKQTRQQSHDSQDYSSFKTVLFYCMLIVFLPVLTFFVLKGFVLDQFLDISEVKVNIASAVGAVVALHIALGLYIYRAYFGTTGSKASKTD
What is the function of this protein?
Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.
What are the official names of this protein?
Vacuolar ATPase assembly integral membrane protein VMA21 homolog.
What is the protein family that this protein belongs to?
Belongs to the VMA21 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein.
Protein: CLPB_MALP2
Sequence: MEFNFEPSNEKDILKKYSRNLNEEVSANKLNKIIGREQEIRRVIEILSRKEKNNPVLIGEPGVGKTAIVEGFVQKIISKEVPENLVHCVVYEVNLSSLIAGTFLQGEFEKRLNALIKEAKQNNGAVILFIDEIHQLMGMGKAGNNSGMDAANILKPIMARGEIKIIGATTSNEYRQYIEKDGALERRFQKILVEEPTPEEALTIMRGLKEKWEIYHKVRIQDNALVASVKLSERYISDKYLPDKAIDLIDEAAAKIKTEAHTSPSEPINKKIFYLETEKIALSKEEGTNQKERINEIEIELEKLKQERDLVEKEWKEQKEQQVALNKIKKEIEKNNWDVERYQNQGEYTEASKILYSVLPELKKKLEAIEKSISENKKVLIKDYISEIDVAEIISRITKIPLNKIFEKEQDKLLNLFNNLKKRVKGQDEALKLVSDTVLKNRVGINNPNRPIGSFLFVGPTGVGKTEVAKSLAENLFNTEKAIVRINMSEYMEKHSISRLIGAPPGYIGYEQAGELSEQIRRKPYSVVLLDEIEKAHPDILNVLLQVLDEGTLKDNQGRNINFKNTIIIMTSNVGALYLMENKEDMFERELKTSFKPEFLNRIDEIIKFNSITMEFAKEIAQKMLDDLEKRLKDNNYQITFDKSVVEYVAKNGYSKEYGARPINRFIQKTIENFITESILKNELIKDRSTIINFANNKLAILKSN
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MENB_STAEQ
Sequence: MTRQWETLREYDEIKYEFFEGIAKVTINRPEVRNAFTPKTVAEMIDAFSRARDDQNVSVIVLTGEGDKAFCSGGDQKKRGHGGYVGEDDIPRLNVLDLQRLIRVIPKPVIAMVRGYAIGGGNVLNVVCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQEALDMGLVNTVVPLEQVEDETVKWCKDIMQHSPTALRFLKAAMNADTDGLAGLQQMAGDATLLYYTTDEAKEGRDAFKEKRNPDFDQFPKFP
What is the function of this protein?
Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
What are the official names of this protein?
1,4-dihydroxy-2-naphthoyl-CoA synthase, DHNA-CoA synthase.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
Protein: SYH_GEOSL
Sequence: MITGIKGFNDILPGEVERWQHIEATARRVFSLYGFSEIRIPILEKTELFRRSIGDTTDIVEKEMYSFVDKGENAVTMRPEGTASVMRSYIEHKLYAQDPVAKLYYMGPMFRYERPQKGRYRQFHQIGAEVTGVTDPKVDAQVLTMLCHYFAELGLTEPTLQINSLGCPECRPAYRQALIDFLRERLDSLCEDCKRRYQTNPLRALDCKSAHCKEATASAPAMLDSLCAGCDDHFTATRRHLERAGTTYSINNRMVRGLDYYTRTTFELVTGLLGAQSAVAAGGRYDGLISDLGGPAIPGIGFAMGVERIALLLGDQHFVGRPDLFIAALGEEAQDEAFRLMCGLQRNGVAVEMDYEGKSLKSQMRRSDKFNARFTLIIGGDELAIGAAVLKAMDTGVQVEVPLTPEEVAARIT
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPF_RHOP2
Sequence: MSVVVKICGLSTRDTLEAAVAAGADMVGFVFFPASPRHVGFDLARALGDQVGSRAAKVALTVDASDALLRDVVDALAPDLLQLHGKESPERVRAIRQTFGLPVMKAVAVATADDLAALPAYAAAADRILFDARPPKDALRPGGLGVPFDWALLSGLALPVPYMVSGGITPGNVAEALRVTRAGGIDVSSGVETAPGVKDSELIRSFIRATRASEETMT
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: TPM2_SCHMA
Sequence: MEHIKKKMLAMKLDKENAVDEADQLEAKLREKELEMQTKDEEVAEVLKKIQQVDTDKETAQTQLAETNTKLEETDKRATEAEAEVASLQKRIRQLEDELESTETRLQEATVKLEEASKAADESDRGRKVLENRTFADEERINQLEEQLKESTFMAEDADRKYDEAARKLAITEVELERAESRLEAAESKITELEEELRIVGNNVKSLEISEQEAAQREEAYEENIRDLTERLKAAEDRAQESERLVNTLQADADRLEDELVTEKEKYKALSEELDSTFAELTGN
What is the function of this protein?
Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction.
What are the official names of this protein?
Tropomyosin-2, Tropomyosin II, SmTMII, TMII.
What is the protein family that this protein belongs to?
Belongs to the tropomyosin family.