PharMolix/UniProtQA huggingface dataset:
Protein: MSRQ_YERPB
Sequence: MRLSLRHITWLKIAIWLAATLPLLWLVLSINLGGLSADPAKDIQHFTGRMALKLLLATLLVSPLARYSKQPLLLRCRRLLGLWCFAWGTLHLLSYSILELGLSNIGLLGHELINRPYLTLGIISWLVLLALALTSTRWAQRKMGARWQKLHNWVYVVAILAPIHYLWSVKTLSPWPIIYAVMAALLLLLRYKLLLPRYKKFRQWFR
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation.  MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ, Flavocytochrome MsrQ.
What is the protein family that this protein belongs to?
Belongs to the MsrQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YD535_YEAST
Sequence: MGQMRWNSGTTALISSTERHYLCKGCKRSISESLLIHTRDHISKFSTLGLNSSAKLCLAILGENTYLRYHIVFLLFLNSFRKFDSEQSATQIFDHGKVTAPIALRIVVACSFSSSAGCGIFECQFSTLKHQIMLVSCLNDGRIYVTLSAFLPVRFLFHCVHLLLSG
What are the official names of this protein?
Putative uncharacterized protein YDR535C.
Protein: RS9_PROMH
Sequence: MADNQYYGTGRRKSSSARVFIKPGSGNIVINKRSLEVYFGRETARMVVRQPLELVDMLGKLDLYITVKGGGISGQAGAIRHGITRALMEYDETLRSDLRKAGFVTRDARSVERKKVGLRKARRRPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: YFCN_SALNS
Sequence: MKKKTSLSEEDQALFRQLMVGTRKIKQDTIVHRPLRKKITEVPTRRLIQEQADASHYFSDEFQPLLNTEGPVKYVREDVSHFELKKMRRGDYSPELFLDLHGLTQLQAKQELGALIAACRREHIFCACVMHGHGKHILKQQTPLWLAQHPHVMAFHQAPKEYGGDAALLVLIEVEEWQPPELP
What are the official names of this protein?
UPF0115 protein YfcN.
What is the protein family that this protein belongs to?
Belongs to the UPF0115 family.
Protein: RS4_TROWT
Sequence: MSSCSRTRLSRALGVPLTPKAARLMEVRPYPPGQHGRFRRKGDSDYAVRLREKQRLRGQYGLREKQLASVYHEARRVKGLAGENLVEMLEMRLDALVLRAAFARSISQARQLVVHRHILVDGKLVDRPSYSVSPGQTVKVKPKSVPLDPFQVAASGGHADVLPPIPGYIEADLEGLSFRLVRRPKRSEVPVTCNVQLVVEYYAAR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: CORA_SHIFL
Sequence: MLSAFQLENNRLTRLEVEESQPLVNAVWIDLVEPDDDERLRVQSELGQSLATRPELEDIEASARFFEDDDGLHIHSFFFFEDAEDHAGNSTVAFTIRDGRLFTLRERELPAFRLYRMRARSQSMVDGNAYELLLDLFETKIEQLADEIENIYSDLEQLSRVIMEGHQGDEYDEALSTLAELEDIGWKVRLCLMDTQRALNFLVRKARLPGGQLEQAREILRDIESLLPHNESLFQKVNFLMQAAMGFINIEQNRIIKIFSVVSVVFLPPTLVASSYGMNFEFMPELKWSFGYPGAIIFMILAGLAPYLYFKRKNWL
What is the function of this protein?
Mediates influx of magnesium ions (By similarity).  Alternates between open and closed states.  Activated by low cytoplasmic Mg(2+) levels.  Inactive when cytoplasmic Mg(2+) levels are high (By similarity).
What are the official names of this protein?
Magnesium transport protein CorA.
What is the protein family that this protein belongs to?
Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PLSX_YERP3
Sequence: MACLTLALDAMGGDFGPCVTVPASLQALASNPQLKLLLVGNPDTITPLLANADSLLLERLQVIPAEHVIASDAKPSQAIRASRGTSMRVALELVKNGEAAACVSAGNTGALMGLAKMMIKPLEGIARPALMTVIPNQRRSKTVVLDLGANVECDSTMLVQFAVMGSVMAEEVVGIVEPRVALLNIGEEENKGLDNIREAAAVLKNTPAINYIGYLEGNDLLTGKTDVMVCDGFVGNVTLKTMEGVIRMFLSLLKPSGEGSKQSWWLKLIGRWLQKRVAKRFGHLNPDQYNGACLLGLRGIVIKSHGAANQRAFAVAIEQAVQAVQRQVPERIAARLEAVLPKSD
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: ATPL_PROM2
Sequence: MDSITSAASVVAAGLAVGLGAIGPGLGQGNAAQGAVEGIARQPEAEGKIRGTLLLSFAFMESLTIYGLVVALVLLFANPFS
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: PDS_ARATH
Sequence: MVVFGNVSAANLPYQNGFLEALSSGGCELMGHSFRVPTSQALKTRTRRRSTAGPLQVVCVDIPRPELENTVNFLEAASLSASFRSAPRPAKPLKVVIAGAGLAGLSTAKYLADAGHKPLLLEARDVLGGKIAAWKDEDGDWYETGLHIFFGAYPNVQNLFGELGINDRLQWKEHSMIFAMPSKPGEFSRFDFPDVLPAPLNGIWAILRNNEMLTWPEKIKFAIGLLPAMVGGQAYVEAQDGLSVKEWMEKQGVPERVTDEVFIAMSKALNFINPDELSMQCILIALNRFLQEKHGSKMAFLDGNPPERLCMPVVDHIRSLGGEVQLNSRIKKIELNDDGTVKSFLLTNGSTVEGDAYVFAAPVDILKLLLPDPWKEIPYFKKLDKLVGVPVINVHIWFDRKLKNTYDHLLFSRSNLLSVYADMSLTCKEYYDPNRSMLELVFAPAEEWISRTDSDIIDATMKELEKLFPDEISADQSKAKILKYHVVKTPRSVYKTIPNCEPCRPLQRSPIEGFYLAGDYTKQKYLASMEGAVLSGKFCSQSIVQDYELLAASGPRKLSEATVSSS
What is the function of this protein?
Converts phytoene into zeta-carotene via the intermediary of phytofluene by the symmetrical introduction of two double bonds at the C-11 and C-11' positions of phytoene with a concomitant isomerization of two neighboring double bonds at the C9 and C9' positions from trans to cis.
What are the official names of this protein?
15-cis-phytoene desaturase, chloroplastic/chromoplastic, Phytoene dehydrogenase, Phytoene desaturase.
What is the protein family that this protein belongs to?
Belongs to the carotenoid/retinoid oxidoreductase family.
What are the subcellular locations of this protein?
Plastid, chloroplast. Plastid, chromoplast. Membrane; Peripheral membrane protein.
Protein: PDPKA_DICDI
Sequence: MENIVITNTSGGGGGGVPSSSTDPPNNTTTTTATASAIDLNMSLSPFLSSPSLSSPSIQSAKKKTIEDFIIGKVLGEGSYGAVVLGTEKETQQQYAIKILEKKQIIKENKIKYVQIEKEIFCKSNHPNIVKLFFTFRSEQCLYYVLELCSQGDLLHQIKKVGSFDYRSCQYYVAEIISGLEHLHSLGIVHRDLKPENILMSSDLHVKITDFGTGKILPPPQSSQQQQQQQQQQQQLPTNSSGNLSSLLNNVNNLSVSTDLTQQQQNRTSSVDSASTTDSMISPNLQPTTTTTNNNNNNNNNNNNNNNNTAAGSNTNTNTNTNINTNINANINNIKTTEIPKLTRNNSFVGTAEYVSPELISNKETSTDSDLWALGCIIYQMASGRVPFRGKTEFLTFQKVSNRELVYPINMNPVIKDLVEKLLVIKPTDRLGSSSTPGGFDNLKAHPFFQDFNWSSLSNMSHPPPPIQPPQEKIIFDGDELFSPSLDCTTPRNNNVDENHQQNSCNNNNNNNNNINNINNNNNSSSNNISNSNSNSNSSNNLNISNGNLSTPRSSSSSSSQQPTQRSGSSGGSRDGGSSSNNISKWLNNGENVIYQGLVWKRKGFSIKKRQLILTDTPRLIYIDPKKMELKGEIPWSDSIKPKLKSNNNFVIKTPKRKYLLEDVAHNPQKWVDSIKSVILSSGSSN
What are the official names of this protein?
Probable serine/threonine-protein kinase pdkA, 3-phosphoinositide-dependent protein kinase A, Pdk-class protein kinase A.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.
Protein: SYWC_RAT
Sequence: MADMPSGESCTSPLELFNSIAAQGELVRSLKAGNAPKDEIESAVKMLLSLKMNYKTAMGEEYKAGCPPGNSTAGSNGDPDATKASEDFVDPWTVRTSSAKGIDYDKLIVQFGSSKIDKELINRIERATGQRPHRFLRRGIFFSHRDMNQILDAYENKKPFYLYTGRGPSSEAMHLGHLVPFIFTKWLQDVFDVPLVIQMSDDEKYLWKDLTLEQAYSYTVENAKDIIACGFDVNKTFIFSDLEYMGQSPGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAVQAAPSFSNSFPKIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGHPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKSKVNKHAFSGGRDTVEEHRQFGGNCEVDVSFMYLTFFLEDDDSLEQIRKDYTSGAMLTGELKKTLIDVLQPLIAEHQARRKAVTEETVKEFMAPRQLSFHFQCFCFDT
What is the function of this protein?
T1-TrpRS has aminoacylation activity while T2-TrpRS lacks it.  T1-TrpRS and T2-TrpRS possess angiostatic activity.  T2-TrpRS inhibits fluid shear stress-activated responses of endothelial cells.  Regulates ERK, Akt, and eNOS activation pathways that are associated with angiogenesis, cytoskeletal reorganization and shear stress-responsive gene expression (By similarity).
What are the official names of this protein?
Tryptophan--tRNA ligase, cytoplasmic, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGR_ALKOO
Sequence: MKYTRHSKILELIDKNEIETQEELSERLKDMGFTVTQATVSRDIKELRLIKVLTKNGKYKYATLQSQENILSDRVVKIFKNSVVSIDYAGNLIVIKTLTGSAQAAAAAIDAGDMNDVVGTIAGDDTIFIVIRDEKNVPSTIEHFRKLMK
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADK_SHIF8
Sequence: MNNHFKCIGIVGHPRHPTALTTHEMLYRWLCTKGYEVIVEQQIAHELQLKNVKTGTLAEIGQLADLAVVVGGDGNMLGAARTLARYDIKVIGINRGNLGFLTDLDPDNAQQQLADVLEGHYISEKRFLLEAQVCQQDCQKRISTAINEVVLHPGKVAHMIEFEVYIDEIFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINSSSTIRLRFSHRRNDLEISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYSYFNTLSTKLGWSKKLF
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRCA_BURMA
Sequence: MLDPRARTLLKTLIERYIADGQPVGSRTLSRYSGLELSPATIRNVMSDLEELGLVSSPHTSAGRVPTPRGYRLFVDTMLTVESPIDSDAVTRLVQTTLQAGEPQQRVVAAAASVLSNLSQFAGVVLTPRRSHVFKQIEFLRLSDKRILLIIVTPEGDVQNRMIATQRDYAPAQLTEASNYINAHFAGLSFDEVRRRLREEIDQLRGDMTALMHAAVTASTEEPDDEETVLISGERNLLEVADLSSDMARLRKLFDVFDQKTSLLQLLDVSSHAQGVQIFIGGESTLVPIDEMSVVTAPYEVNGKIVGTLGVIGPTRMAYNRVIPIVDITARLLSLTLSQQ
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: ELP3_DROME
Sequence: MKAKKKLGVGLSRQERQVLVIGEIIQELLKAHEAKKDVNLNRMKSLVASKYGLDSSPRLVDIIAAVPQDAKKILLPKLRAKPIRTASGIAVVAVMCKPHRCPHINMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRSRYDPFLQTRHRVEQLKQLGHSVDKVEFIVMGGTFMCLPEEYRDYFIRNLHDALSGHSSANVAEAVRYSEKSRTKCIGITIETRPDYCLKRHISDMLSYGCTRLEIGVQSVYEDVARDTNRGHTVRAVCESFQLGKDAGYKIVTHMMPDLPNVDFERDIEQFIEYFENPAFRSDGLKIYPTLVIRGTGLYELWKTGRYKSYPPSMLVDLVAKILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGTTCRDVRTREVGIQEIHNKVRPYEIELIRRDYVANGGWETFLSYEDPEQDILVGLLRLRKCSPDTFRPELKGECSIVRELHVYGSVVPVNARDPTKFQHQGFGMLLMEEAERIAREEHGSTKLAVISGVGTRNYYRKMGYQLDGPYMSKSIEENN
What is the function of this protein?
Catalytic tRNA acetyltransferase subunit of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) (By similarity).  In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (By similarity).  Plays a role in the control of synaptic bouton expansion (PubMed:20626565).  Required for larval development (PubMed:21288872).
What are the official names of this protein?
Elongator complex protein 3, tRNA uridine(34) acetyltransferase.
What is the protein family that this protein belongs to?
Belongs to the ELP3 family.
Protein: SYN_ECO57
Sequence: MSVVPVADVLQGRVAVDSEVTVRGWVRTRRDSKAGISFLAVYDGSCFDPVQAVINNSLPNYNEDVLRLTTGCSVIVTGKVVASPGQGQQFEIQTSKVEVAGWVEDPDTYPMAAKRHSIEYLREVAHLRPRTNLIGAVARVRHTLAQALHRFFNEQGFFWVSTPLITASDTEGAGEMFRVSTLDLENLPRNDQGKVDFDKDFFGKESFLTVSGQLNGETYACALSKIYTFGPTFRAENSNTSRHLAEFWMLEPEVAFANLNDIAGLAEAMLKYVFKAVLEERADDMKFFAERVDKDAVSRLERFIEADFAQVDYTEAVTILENCGRKFENPVYWGVDLSSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLNEDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDERMLEMGLNKEDYWWYRDLRRYGTVPHSGFGLGFERLIAYVTGVQNVRDVIPFPRTPRNASF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF5A_METAC
Sequence: MKQQVEVKDLKEGKYVIIDDEACVIKSISKSKPGKHGAAKARVEAIGLFDNQKRSYIGSVANKIYVPIVERKSAQVISITGDIAQLMDMGDFSTFEIVIPDEYKDKVKEGEEVSYITALGKIKLDIRT
What is the function of this protein?
Functions by promoting the formation of the first peptide bond.
What are the official names of this protein?
Translation initiation factor 5A, Hypusine-containing protein, eIF-5A.
What is the protein family that this protein belongs to?
Belongs to the eIF-5A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_MARMS
Sequence: MKTFTAKPAEVRRDWFVVDAEGKTLGRLATEIARRLRGKHKAEYTPHVDTGDYIVVINAEKIHVTGNKAAAKQYYRHTGYPGGLRSMNFEKLIDHAPERVLEIAVKGMLPKGPLGRAMHKKMKVYAGTEHPHAAQQPQALNI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: NFD4_ARATH
Sequence: MRPRIRDVSDKLRPNRASFDDGETKFHRKHLPPLRTMFGRWRKWTVLVAAIWIQASTGTNFDFSAYSSHLKSVLGISQVRLNYLAVASDLGKAFGWSSGIALGYFPLSVVLFAAAAMGFVGYGVQWLVITNIITLPYSLVFLCCLLAGLSICWFNTACFILCIRHFPNNRALALSLTVSFNGISAALYSLAFNAINPSSSNLYLLLNSLVPLVVSFAALYPVLTKPSLDTTPDYDSRRHDSHVFTILNVLAVITSFHLLLSSSSTSSARLNFIGAVVLLVFPLCAPLLVYARDYFLPVINARLNHESSGYVMLNIDELKNQKTSVSSKTGYEHMGTAKEGNTVRLGDEHSFRLLISRLEFWLYYIAYFCGGTIGLVYSNNLGQIAQSLGQNSTTLVTIYSSFSFFGRLLSAAPDFMHKRFRLTRTGWFAIALLPTPIAFFLLAVSSSQQTALQTATALIGLSSGFIFAAAVSITSDLFGPNSVGVNHNILITNIPIGSLLYGYIAASIYEANASPDITPIVSDSIVCIGRDCYFKTFVFWGCLSILGVVSSLSLYIRTKPVYHRLEQDKVSLTSSYKDLDPL
What is the function of this protein?
Required for karyogamy during female gametophyte development, when the two polar nuclei fuse to form the diploid central cell nucleus (PubMed:16698901).
What are the official names of this protein?
Protein NUCLEAR FUSION DEFECTIVE 4.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: COX10_YEAST
Sequence: MSYFPRTYAHLMRNVLAHNKGNIYLQIGTQLHDTQIKIRFNGVRYISRNHGGKQQHINTAPIEFTPNFGYGDRTSNCNKKVESTAMKTLRCTDDISTSSGSEATTDASTQLPFNVKLVDPMVRKSKRPSHAISEGLNMKTLKKKVIMPYLQLTKPRLTILVMLSAICSYALSPYPASVNELLCLTVGTTLCSGSANAINMGREPEFDRQMVRTQARPVVRGDVTPTQAFEFAALIGTLGVSILYFGVNPTVAILGASNIALYGWAYTSMKRKHIINTWLGALVGMVPPLMGWAAASPLSHPGSWCLAGLLFAWQFPHFNTLSHNIRNEYKNAGYVMTAWKNPLLNARVSLRYSILMFPLCFGLSYFNITDWYYQIDSGLINAWLTFWAFKFYWQQRINYSAKTLKDNVKFNKGLSVANIYARKTFMASVLHLPAILILAIIHKKGRWDWIYPGEAKRPQERF
What is the function of this protein?
Converts protoheme IX and farnesyl diphosphate to heme O.
What are the official names of this protein?
Protoheme IX farnesyltransferase, mitochondrial, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: DXS_ERWT9
Sequence: MSFETAKYPTLALASTVQELRLLPKESLPTLCDELRQYLLDSVSRSSGHFASGLGVVELTVALHYVYNTPFDHLIWDVGHQAYPHKILTGRRDRIGTIRQKNGLHPFPWRDESEYDVLNVGHSSTSISAGLGMAVAAGKEAQGRRTACVIGDGAITAGMAFEAMNHAGDCKADLLVVLNDNEMSISENVGALNNRLAQILSGKTYSRLRESGKKVLDGLPPIKELVKRTEEHLKGMVVPGTLFEELGFNYIGPVDGHDVLALVHTLRNMRALKGPQFLHVMTKKGKGYAPAEKDPISWHAVPKFDPASGLLPKSAEGLPSYSKIFGQWLSETAAADDRLMAVTPAMREGSGMVSFSRDYPQQYFDVAIAEQHAVTFAAGLAIGGYKPVVAIYSTFLQRAYDQLIHDVAIQKLPVLFAIDRGGIVGADGQTHQGAFDIAFLRCIPDMVIMTPSDENECRQMLYTGYHHQGGPSAVRYPRGNGTGAPLEALASLPLGKGVVKRRGEKMAILNFGTLLPQAAEVAEAINATLVDMRFVKPLDEALVLELAAQHQSLITLEEGSIKGGAGSGVNELLMAKRRAIPVLNIGLPDEFIPPGTQDEIRSDYQLDADGIQRQIADWLAQ
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: YNR1_YEAST
Sequence: MSCTPFINQVIHKDYTLPQFWNLLKLVLDTQINILEFCIIHHVVQSFCTTIRVGNPKYLHCFYLNTANLNYKILNPLMLYYFLHSKEYRVPPLSNLEYPNFQPVAKRWYFLVHFLGLILNNF
What are the official names of this protein?
Putative uncharacterized protein YNL171C.
Protein: PVK2_CRYDW
Sequence: GSSGLISMPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-2, CryDa-PVK-2.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ASB9_MOUSE
Sequence: MDGEQRGRSDRPGGSPHLPFLSNPLMGDVVSDWSPLHDAAIHGCLLTLRNLISQGWPVNIITADHVSPLHEACLRGHLSCASVLLSHGAQVNGMTIDWRTPLFNACVSGSQDCVNLLLQHGATPHPETELASPIHEAAKRGYVKCIESLAAHGANIDYNISHLGTPLYVACKNQQVACAKKLLESGVSVNQGKGLDSPLHVVARMSSVELVHLLMDFGANAQAKNADGKRPVDLVPLESPLIQIFLQNEGPQSLRQLCRLRIRKCFGIRQHHKISELLLPEDLKRFLLHL
What is the function of this protein?
Substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.  Recognizes at least two forms of creatine kinase, CKB and CKMT1A (By similarity).
What are the official names of this protein?
Ankyrin repeat and SOCS box protein 9, ASB-9.
What is the protein family that this protein belongs to?
Belongs to the ankyrin SOCS box (ASB) family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: COBQ_MYCUA
Sequence: MPGLLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGRAQWVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLADTAHRAFDDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLARHAELPTIVVGDIDRGGVFAAFFGTIALLSVEDQALVAGFVVNKFRGDLDLLAPGLRDLERVTGRQVFGTLPWHADLWLDSEDALDLTGRRAASAGAHRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLIVVPGTRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGPVAEADGLGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAGDAAQQFLGGARDGQVFGTMWHGSLEGDALREAFLRETLGLTESGTSFSAARERRLDLLGDLVERHLDVDALLALARHGCAPALPFLPPGAP
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: RCLA_ECOLI
Sequence: MNKYQAVIIGFGKAGKTLAVTLAKAGWRVALIEQSNAMYGGTCINIGCIPTKTLVHDAQQHTDFVRAIQRKNEVVNFLRNKNFHNLADMPNIDVIDGQAEFINNHSLRVHRPEGNLEIHGEKIFINTGAQTVVPPIPGITTTPGVYDSTGLLNLKELPGHLGILGGGYIGVEFASMFANFGSKVTILEAASLFLPREDRDIADNIATILRDQGVDIILNAHVERISHHENQVQVHSEHAQLAVDALLIASGRQPATASLHPENAGIAVNERGAIVVDKRLHTTADNIWAMGDVTGGLQFTYISLDDYRIVRDELLGEGKRSTDDRKNVPYSVFMTPPLSRVGMTEEQARESGADIQVVTLPVAAIPRARVMNDTRGVLKAIVDNKTQRMLGASLLCVDSHEMINIVKMVMDAGLPYSILRDQIFTHPSMSESLNDLFSLVK
What is the function of this protein?
Probably involved in reactive chlorine species (RCS) stress resistance.
What are the official names of this protein?
Probable pyridine nucleotide-disulfide oxidoreductase RclA, Reactive chlorine resistance protein A.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
Protein: SSRP_PSEPW
Sequence: MAKQKKHPTGTIAQNKKARHDYFIEHKFEAGLVLSGWEVKSLRAGKAHLTDSYVLLKDGEAWLFGSHITPLTTASTHVIADPIRSRKLLLNKRELERVEAAVAQKGYTCVALALYWSKHLIKCEIALGKGKKEFDKRDTVRERDSNRELQRAVRNKGKED
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: METK_NITHX
Sequence: MRGSYLFTSESVSEGHPDKVCDRISDEIVDLFFSEGPKAGVDPWAIRAACETLATTNKVVIAGETRGPESVTKEKIESVVRAAIKDIGYEQDGFHWKTADIDILLHPQSADIAQGVDALQPGANKEEGAGDQGIMFGYACNETPDLMPAPIFYAHKILRLISEARHSGKEKVLGPDSKSQVTVQYENGKPVGVREIVVSHQHLIEDMSSDQVRERVEPYVREALPKAWVTDKTIWHINPTGKFFIGGPDGDAGLTGRKIIVDTYGGAAPHGGGAFSGKDPTKVDRSAAYAARYLAKNIVAAGLADRCTLQLAYAIGVARPLSIYIDTHGTGKAPEDTLERIVSEAMDLTPRGIRKHLDLNRPIYARTSSYGHFGRTPDNEGGFSWEKTDLAEVLKRAV
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CECC_HELVI
Sequence: RWKVFKKIEKMGRNIRDGVIKAAPAIEVLGQAK
What is the function of this protein?
Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria.  Has also activity against fungi.
What are the official names of this protein?
Cecropin-C.
What is the protein family that this protein belongs to?
Belongs to the cecropin family.
What are the subcellular locations of this protein?
Secreted.