PharMolix/UniProtQA huggingface dataset:
Protein: EFP_ECOLC
Sequence: MATYYSNDFRAGLKIMLDGEPYAVEASEFVKPGKGQAFARVKLRRLLTGTRVEKTFKSTDSAEGADVVDMNLTYLYNDGEFWHFMNNETFEQLSADAKAIGDNAKWLLDQAECIVTLWNGQPISVTPPNFVELEIVDTDPGLKGDTAGTGGKPATLSTGAVVKVPLFVQIGEVIKVDTRSGEYVSRVK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_PSEPG
Sequence: MNSLAPVITIDGPSGSGKGTVAGLLARELGWKLLDSGALYRLLAFNASNHGVDLTNEELLTKLAAHLDVQFIAAEPGKLQQIILEGEDVSNVIRTETVGAGASMVASLPAVRDALLVRQREFRDVPGLIADGRDMGTVVFPDAPLKVFLTASAEERARRRYLQLKGKGEDVSLSSLLDEIRARDERDTQRAVAPLKPAADAIQLDSTELSIEQVLQRIRSEIAQRDLA
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2B4_ORYSJ
Sequence: MAPKAEKKPAAKKPAEEEPAAEKAEKAPAGKKPKAEKRLPAGKAEKGSGEGKKAGRKKAKKSVETYKIYIFKVLKQVHPDIGISSKAMSIMNSFINDIFEKLAGESAKLARYNKKPTITSREIQTSVRLVLPGELAKHAVSEGTKAVTKFTSA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.4.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RL361_YERPS
Sequence: MKVRASVKKLCRNCKIVKRNGVVRVICSAEPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: URED_BLOFL
Sequence: MFNGFDQGDFLSKSSDDWISRLELNFVLQEGCSVLKKISHIGPILVQKIFYPENDKSNIPHVYLLQPSGGLVGGDQIHISVCLESGSKVLLTTPGSTKFYRTNGKYILQEHIFKLKDNTSLEWLPQSSIFFPNTKVKINTIFHLEPGARIIIGEILCFGSDGWLDNYGSPDVIDIFLRICLPYCSGLRDRLKIDSQNYIDKLHGFKISASLFAAPSNKETLKVVRSLITSTVDIQIGGVTLIDELLVVRLLSNNNQRIKELLYHIWSVIRPIIIGQEAVMPRVWFT
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAP21_TALSN
Sequence: MAAQADDELNKLRLNGQNGEAKEQVSASAVDTADNDDSEDDEKEEEGGAEVAATEAAKKKKKRKPKKKKKGGAKKQSSPPRVPVSELFPNNQYPEGEIVEYKDENNYRTTNEEKRYLDRMNNDFLQEYRQGAEVHRQVRQYAQKNIKPGQTLTEIAEGIEDAVRALTGHQGLEEGDNIKGGMGFPCGLSINHCAAHYTPNAGNKMVLQQGDVMKVDFGAHINGRIVDSAFTMTFDPVYDNLLTAVKEATNTGIREAGIDVRMSDIGAAIQEVMESYEVEINGTTYPVKAIRNLNGHNIDQHVIHGGKSVPIVKGGDQTKMEEGEVFAIETFGSTGKGYVREDMETSHYAKAQDAPNVSLRLSSAKNLLNVINKNFGTLPFCRRYLDRLGQDKYLLGLNNLVSAGIVQDYPPLCDIKGSYTAQYEHTIVLRPTVKEVISRGDDY
What is the function of this protein?
Cotranslationally removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
What are the official names of this protein?
Methionine aminopeptidase 2-1, MAP 2-1, MetAP 2-1, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA_COXBR
Sequence: MEPFKHPIAILGAGSWGTALALVLARKGQKVRLWSYESDHVDEMQAEGVNNRYLPNYPFPETLKAYCDLKASLEGVTDILIVVPSFAFHEVITRMKPLIDAKTRIAWGTKGLAKGSRLLHEVVATELGQVPMAVISGPSLATEVAANLPTAVSLASNNSQFSKDLIERLHGQRFRVYKNDDMIGVELCGSVKNILAIATGISDGLKLGSNARAALITRGLTEMGRLVSVFGGKQETLTGLAGLGDLVLTCTDNQSRNRRFGLALGEGVDKKEAQQSIGQAIEGLYNTDQVHALAQKHAIEMPLTFQVHRILHEDLDPQQAVQELLERSPKAE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_BACCR
Sequence: MSKIRVHEYAKKHNISSKDLMTKLKEMNIEVSNHMTMLDDEVVNKLDNEYQTEKPSVADEFEVEEKVVRSKKNSNKKKKKGKGNEDKRQENFAGRQQTQIVETPDKITFSGSLTVGDLAKKLSKEPSEIIKKLFMLGIMATINQDLDKDTIELIANDYGIEVEEEVIVSETEFETFIDEQDDEENLKERPAVVTIMGHVDHGKTTLLDSIRNSKVTAGEAGGITQHIGAYQVEVNDKKITFLDTPGHAAFTTMRARGAQVTDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKMDKPAANPDRVMQELTEYELVPEAWGGDTIFVPISAIQGEGIDNLLEMILLVSEVEEYKANPNRYATGTVIEAQLDKGKGTIATLLVQNGTLRVGDPIVVGTSFGRVRAMVSDIGRRVKVAGPSTPVEITGLNEVPQAGDRFMAFADEKKARQIGESRAQEALVAQRGEKSKLSLEDLFQQIQEGDVKEINLIVKADVQGSVEAMAASLRKIDVEGVKVKIIHTGVGAITESDIILASASNAIVIGFNVRPDVNAKRTAELENVDIRLHRIIYKVIEEIEAAMQGMLDPEFEEKVIGQAEVRQTFKVTKVGTIAGCYVTDGKITRDSGVRIIRDGVVIFEGQLDTLKRFKDDVKEVAQNYECGITIERYNDLKEGDIIEAYIMEEVKR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YFRC_PROVU
Sequence: MCLGIPGQVVEVGKTITENALVDVCGVKREVNIALVCEGEPDTMIGKWVLVHVGFAMSIVNEQEAQETLNALMAMGEVEDDVSAFLYGEESTAKRA
What are the official names of this protein?
Frd operon uncharacterized protein C.
What is the protein family that this protein belongs to?
Belongs to the HupF/HypC family.
Protein: AMPA_SYNP2
Sequence: MEIRGSSQTAAAWAGEAIALGFFESETVLTVPENLTALDERLSGVIAEVIAETEFKGKSGKLSVTRLGSGAPIKKLLLVGLGNAEKWNSAVLRSTAAAIARAVKGDKAITTLGLQLPVAETEAITAQMVTEGMYLGFYEDNRFKSEQKDPPALEAVEILGIGDQPAAIALGTSLCEGVIYARELVNAPANIINPVTLAASVESLASTYGLELNILEEADCEAAGMGSFLGVAAASDLPPKFIHLVYKPLGTPRKKVAIVGKGLTFDSGGYNIKPSGPSIAMMKMDMGGAAATFGAAKAIAELKPDVEVHFISAATENMISGRGMRPGDILTASNGKTIEVNNTDAEGRLTLADALVYAEKLGVEAIVDIATLTGACVIALGDDICGLWSDNDDLAQAIATASEKAGEKFWQMPLEEKYFEGLKSPIADMKNTGPREGGSITAALFLKEFVENTPWAHLDIAGPAWSEKDADIYSKGGTGFPVRTLVHWVLS
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_SALSV
Sequence: MALNLQDKQAIVAEVSEVAKGALSAVVADSRGVTVDKMTELRKAGREAGVYMRVVRNTLLRRVVEGTQFECLKDTFVGPTLIAYSMEHPGAAARLFKEFAKANAKFEVKAAAFEGELIPASQIDRLATLPTYEEAIARLMATMKEASAGKLVRTLAAVRDAKEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: KHSE_BUCAT
Sequence: MIKIYAPASIGNVGVGFDILGAAIIPINGSLLGDFVTVKLSNKFNLVNKGIFSNKLPKNTEQNIVWKCWLKFCNTIKRNIPVSIILEKNMPIGSGLGSSACSIVATLVAMNEFCDKPLNSKELLLLMGEVEGEISGSIHYDNVAPCYLGGLQLILEDSKIISQTIPNFKNWFWIVAWPGTKVPTAEARDILPKKYKKETCIKNSRYLAGFIHASYSQQPHLAARLMQDFIAEPYRIKLLPNYLYVKEKIKKIGAISSGISGSGPTIFSISDNINTAQKISAWLTENYLQNTTGFVHICFLDSKGVRKIG
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_FRATW
Sequence: MAKVSKRMKEISAKINAEKKYPVSEAFDLLREVSSVKFVESVDVSVALGVDPRKSDQVVRGASVLPNGTGKTVRVAVFAKGPAADAAKEAGAEVVGMEDLADEVKKGNMDFDVVIASPDSMRVVGQLGQILGPKGLMPNPKVGTVTMDVAKAVRDAKAGQVRYRVDKAGIIHTTIGKVNFTSDALKQNLERLLTDLKKAKPAVSKGIYLKKVSVSSTMGPGINVDFSDLNI
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: NDHK_CYCTA
Sequence: MGSTESPLLGQTTPNSVISTTLNDLSNWARLSSLWPLLYGTSCCFIEFASLIGSRFDFDRYGLVPRSSPRQADLIITAGTVTMKMAPSLVRLYEQMPGPKYVIAMGACTITGGMFSTDSYSTVRGVDKLIPVDVYLPGCPPKPEAIIDAIIKLRKKVAREIYEDRTKLQQGKRYFTQNHKFRVGSSLYTGNYDQKLLHKSPEPQSESTSEILSKTFESTSEIPSDFVKYENSVSFQESRNEEYFVKSNEQEINFQKFHWKC
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit K, chloroplastic, NAD(P)H dehydrogenase subunit K, NADH-plastoquinone oxidoreductase subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: LEUC_ACIF2
Sequence: MSAKTLYDKLWESHVVHTEQDGGVLLYIDRQLLHEVTSPQAFSGLRAAGRKAWRIDANIATADHNVPTTDRAAGIADATSRLQVDTLDRNCAEFGIEEFGMHDKRQGIVHVIAPEQGLTLPGMTVVCGDSHTATHGALGALAFGIGTTEVEHVLATQCLWARKSRSMRIWVEGELGNGVTAKDLVLAIIGRIGTAGGTGYAIEFAGPAVHALSVEGRMTLCNMAIEAGARSGMVGVDAVTIDYLRGRPYAPVGKIWDQAVAVWGELHSDPDAQFDAEIRLEATDVAPQVTWGTSPEMVVDISARVPDPALEKDPVRRKGWSDALAYMDLAAATPISSIALDKVFIGSCTNARIEDLRAAAAVARGHHKAASVKAVLVVPGSGLVKAQAEAEGLDRIFRDAGFEWREPGCSMCLAMNADRLEPGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAAIAGHFVDVRDWIMH
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: CSTR4_ORYSJ
Sequence: MQRNGVMECSVCHSKVVAPSPRSVSRAYDKHRSKISSKYRALNFLLVSGDCILVGLQPILVFMSKVDGKFQFSPISVNFLTEVTKVIFAIVMLIIQSRKQKVGEKPLLSLSTFVQAARNNALLAVPALLYAINNYLKFIMQLYFSPATVKMLSNLKVLVIAILLKFIMRRKFSIIQWEALALLLIGISVNQLSSIPDGTKSFGLAVTTIAYIYTLIFVTVPSLASVYNEYALKSQFDTSIYLQNLFLYGYGAIFNFLGILGTVIFQGPESFDILRGHSRATMFLICNNAAQGILSSFFFKYADTILKKYSSTVATIFTGLASAAFLGHTLTVNFLLGISIVFISMHQFFSPLAKVKDDKPAGALEPEDAQNHRSSDSSFVNMTAGAADDASHLTATDERKPLLPI
What is the function of this protein?
Sugar transporter involved in the transport of CMP-sialic acid from the cytoplasm into the Golgi.  May transport important nucleotide sugars such as CMP-Kdo (2-keto-3-deoxy-D-manno-octulosonic acid) in physiological conditions.
What are the official names of this protein?
CMP-sialic acid transporter 4, CMP-SA-Tr 4, CMP-Sia-Tr 4, CMP-sialic acid transporter-like protein 4.
What is the protein family that this protein belongs to?
Belongs to the nucleotide-sugar transporter family. CMP-Sialate:CMP antiporter (TC 2.A.7.12) subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: RL16_THEM4
Sequence: MLMPKRVKYRKQHRGRMKGKAKGGSLVAFGDYGLKALEAHWITAQQIEACRIAITRTLKKSGKLWIRIFPDKSYTKHPAESKLGKGKGNVEGWVAVVKPGRVMFEIGGVSEELAREALEYAATKLPIRTKIVKRHEIGGEAV
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: RLMH_HYPNA
Sequence: MRLQILAVGRLKDGPERDLTDDYIRRASAMARGLGFKGPEEAEIASGGGMDAEGARLLARIPEGARIIRLDEGGENLTSEAFASRLSRWRDDGERDTCFLIGGAEGYAPDVRAAAPQTLAFGVQTWPHRLVRAMLAEQLYRAMTILAGTPYHKA
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC2_AETGR
Sequence: MGERANLVFHNKIIDGTAIKRLISRLIDHFGMAYTSHILDQVKTLGFQQATATSISLGIDDLLTIPSKGWLVQDAEQQSLILEKHHHYGNVHAVEKLRQSIEIWYATSEYLRQEMNPNFRMTDPFNPVHMMSFSGARGNASQVHQLVGMRGLMSDPQGQMIDLPIQSNLREGLSLTEYIISCYGARKGVVDTAVRTSDAGYLTRRLVEVVQHIVVRRTDCGTIRGISVSPRNKNRMMSEPIFIQTLIGRVLADDIYIGSRCVAFRNQDLGIGLVNRFITFGTQSISIRTPFTCRSTSWICRFCYGRSPTHGDLVELGEAVGIIAGQSIGEPGTQLTLRTFHTGGVFTGGTAEHVRAPYNGKIKFNEDLVHPTRTRHGHPAFLCYIDLSVIIESEDIIHSVTIPPKSFLLVQNDQYVESEQVIAEIREGTYTFRFKERVRKYIYSDSEGEMHWSTDVYHAPEFTYSNVHLVPKTSHLWILSGGSCGSSLISFSIHKDQDQMNIPFLSVKRKSICSLSVNNDQVSQKFLSSDFSDKKKSGIPDYSELNGIVGNSHYNLIYSAIFHENSDLLAKRRRNRFLIPFQSIQEQEKEFMPHSGISIAIPINGIFRKNSIFSFFDDPRYRRKSSGILKYGTIEADSIIQKEDMIEYRGVHKFKKKYKMKVDRFFFIPEEVHILPESSVIMVQNYSIIRVDTRITLNIRSQVGGLIRVERKKKRIELKIFSGDIHFPDKTDKIFRHSGILIPPGRGKPNSRESKKVQNWIYVQRITPTKKKFFVLVRPVATYEIADSINLATLFPQDLFREKNNIQLRVVNYILYGNGNPTRGISDTSIQLVRTCLVLNWDQDNKKSSLEEARAFFVAVSTKGLIRDFIRIGLVKSHISYIRKRTNPPDSGLISADHMNPFYSISPKAGIQQSLSQNNGTIRMFLNRNKESQFLLILSSSNCFRMGPFNHVKYHNVINQSIKKNPLITIQKASGPLGTTIQISNFYSFFPLLTYNKMSVIKYLQLDNLKQILKVINSYLIDENGRICNRDPYSNVVLNPFKLNWYFLHQNYHHNYCEEISTIISLGQFFCENLCIAKKGPHLKSGQVLIVQMDSVVLRCAKPYLATPGAKVHGHYGEILYEGDTLVTFIYEKSRSGDITQGLPKVEQVLEVRSIDSISMNLEKRIKGWNKYITRILGIPWGFLVGAELTIVQSRISLVNKIQKVYRSQGVQIHNRHIEIIVRQITSKVLVSEEGMSNVFLPGELIGLLRAERTGRALEEAICYRAILLGITRASLNTQSFISEASFQETARVLAKAALRGRIDWLKGLKENVVLGGGIPAGTGFNKGLVHCSRQHTNILLEKKTKNLCLFEEDMRDILFYHREFFDSSISKLERSFLGFNYS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta'', PEP, Plastid-encoded RNA polymerase subunit beta'', RNA polymerase subunit beta''.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: IL21_CANLF
Sequence: MEKIVICLMVIFLGTVAHKSSFQEQDLLLIRMRQLIDIVDQLKNYVNDLDPESLPAPEDVKRHCERSAFSCFQKVQLKAANTGGNEQIINVLTKQLKRKLPPTNAGRRQKHRPACPSCDSYEKAPPKEFLERLKSLIQKMIHQHLS
What is the function of this protein?
Cytokine with immunoregulatory activity.  May promote the transition between innate and adaptive immunity.  Induces the production of IgG(1) and IgG(3) in B-cells.  Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers.  Together with IL6, control the early generation of Tfh cells and are critical for an effective antibody response to acute viral infection (By similarity).  May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15.  May regulate proliferation of mature B- and T-cells in response to activating stimuli.  In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells (By similarity).  During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation (By similarity).
What are the official names of this protein?
Interleukin-21, IL-21.
What is the protein family that this protein belongs to?
Belongs to the IL-15/IL-21 family.
What are the subcellular locations of this protein?
Secreted.
Protein: NDK_YERE8
Sequence: MAVERTFSIIKPNAVAKNNIGAIYARFESAGFKIIAAKMLHLTKEQAEGFYAEHKGRPFFDGLVEFMTSGPVMIQVLEGENAVQRHRDIMGATNPDNALAGTLRADFADSFTENAVHGSDAVESAQREIAYFFSENEICPR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F16P1_MOUSE
Sequence: MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK
What is the function of this protein?
Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis.  Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells.  Appears to modulate glycerol gluconeogenesis in liver.  Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.
What are the official names of this protein?
Fructose-1,6-bisphosphatase 1, FBPase 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase 1, Fructose-1,6-bisphosphatase isozyme 3, FBPase 3, Liver FBPase.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
Protein: OTULL_RAT
Sequence: MKATRSAPRERERSRTTSGSDQVHSWILVPSQVLHAVWRIARASVMTALSLLSATLSYFRSLYLYLGHQLKWWIGYLQRKFKRNLSVEAEVDLLSYCAREWKGETPRARLMRKAYEELFWRYHVKCVRPVKRDNYDALRSVLFQIFSQGLSFPSWMKEKDIVKLPEKLLFSQGCNWIQQYSFGPEKYTGSNVFGKLRKCVELLKLQWTEFSGMRDYHKRGSMCNSLFSDAILECKLYEALKFLMLYQVTEVYEQMKTNKIVPSLFRLLFSRESSPDPLSFMMNHLNSIGDTCGLDQIDMFILGYSLQVKIKVFRLFKFNSRDFAVYYPEEPLREWPEISLLTENDHQYHIPVF
What is the function of this protein?
Lacks deubiquitinase activity.
What are the official names of this protein?
Inactive ubiquitin thioesterase OTULINL.
What is the protein family that this protein belongs to?
Belongs to the peptidase C65 family. Otulin subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein. Nucleus envelope.
Protein: TRPF_MYXXD
Sequence: MSVRVKVCGVTRLSDAVAAWEAGVDALGLNFYPKSPRYLDLPTAAALARTRPPLGTVLGVFVNAAPDTIRETVRACGLTAVQLHGDEPPEACSGYGVPVIKALRVTGPEDVVRARTYVGVGDVAGLLLDGAAPGYGGGGVGFDWSLVAGLAGSGVPVLVAGGLRPSNVAEAVRATRPYGVDVASGVESAPGIKDVEAVRAFVRAAKSINLWE
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: RNS6_NICAL
Sequence: MFNLPLTSVFVIFLFALSPIYGAFEYMQLVLQWPTAFCHTTPCKNIPSNFTIHGLWPDNVSTTLNFCGKEDDYNIIMDGPEKNGLYVRWPDLIREKADCMKTQNFWRREYIKHGTCCSEIYNQVQYFRLAMALKDKFDLLTSLKNHGIIRGYKYTVQKINNTIKTVTKGYPNLSCTKGQELWFVGICFDSTAKNVIDCPNPKTCKTASNQGIMFP
What is the function of this protein?
Self-incompatibility (SI) is the inherited ability of a flowering plant to prevent self-fertilization by discriminating between self and non-self pollen during pollination.  In many species of the Solanaceae, self-incompatibility is controlled by the single, multiallelic locus S.  This stylar glycoprotein is associated with expression of self-incompatibility in potato.
What are the official names of this protein?
Ribonuclease S-6, S6-RNase, Stylar glycoprotein 6.
What is the protein family that this protein belongs to?
Belongs to the RNase T2 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: RL10_PSEF5
Sequence: MAIKLEDKKAIVAEVNEAAKAALSAVVADARGVTVGAMTGLRKEAREAGVYVRVVRNTLLKRAVEGTQYDVLNDAFVGPTLIAFSKEHPGAAARIFKEFAKGQEKFEIKAAAFEGKYLAANEIDVLASLPTRDEAIAKLMSVIQGATSKLARTLAAIRDQKEAAAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.