PharMolix/UniProtQA huggingface dataset:
Protein: PHCB_SYNY3
Sequence: MFDVFTRVVSQADARGEYLSGSQLDALSATVAEGNKRIDSVNRITGNASAIVSNAARALFAEQPQLIQPGGNAYTSRRMAACLRDMEIILRYVTYATFTGDASVLEDRCLNGLRETYVALGVPGASVAAGVQKMKEAALDIVNDPNGITRGDCSAIVAEIAGYFDRAAAAVA
What is the function of this protein?
Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex (phycobilisome, PBS).  Phycocyanin is the major phycobiliprotein in the PBS rod.
What are the official names of this protein?
C-phycocyanin beta subunit.
What is the protein family that this protein belongs to?
Belongs to the phycobiliprotein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=Part of the phycobilisome rod.
Protein: TRMB_MARN8
Sequence: MTDQNETQDTNPVTTRRGVRSFVLRQGRMTEGQKKAFDRNWAKYGLSRDNGMIDPREVFGRDNMLNLEIGFGMGKSLADMAEAAPEQDFIGVEVHLPGVGALLKEVESRGLENVRVYSIDANDVIDLCLPDACLDRVMVFFPDPWHKKKHHKRRLIQPEFVQRIRHKLRVGGILHLATDWENYAEHMLEVMSASEGFANTQEQGGYSPKPDDRPITKFEKRGESLGHGVWDLLFYRTN
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: TOM1_HUMAN
Sequence: MDFLLGNPFSSPVGQRIEKATDGSLQSEDWALNMEICDIINETEEGPKDALRAVKKRIVGNKNFHEVMLALTVLETCVKNCGHRFHVLVASQDFVESVLVRTILPKNNPPTIVHDKVLNLIQSWADAFRSSPDLTGVVTIYEDLRRKGLEFPMTDLDMLSPIHTPQRTVFNSETQSGQDSVGTDSSQQEDSGQHAAPLPAPPILSGDTPIAPTPEQIGKLRSELEMVSGNVRVMSEMLTELVPTQAEPADLELLQELNRTCRAMQQRVLELIPQIANEQLTEELLIVNDNLNNVFLRHERFERFRTGQTTKAPSEAEPAADLIDMGPDPAATGNLSSQLAGMNLGSSSVRAGLQSLEASGRLEDEFDMFALTRGSSLADQRKEVKYEAPQATDGLAGALDARQQSTGAIPVTQACLMEDIEQWLSTDVGNDAEEPKGVTSEEFDKFLEERAKAADRLPNLSSPSAEGPPGPPSGPAPRKKTQEKDDDMLFAL
What is the function of this protein?
Adapter protein that plays a role in the intracellular membrane trafficking of ubiquitinated proteins, thereby participating in autophagy, ubiquitination-dependent signaling and receptor recycling pathways (PubMed:14563850, PubMed:15047686, PubMed:23023224, PubMed:25588840, PubMed:26320582, PubMed:31371777).  Acts as a MYO6/Myosin VI adapter protein that targets MYO6 to endocytic structures (PubMed:23023224).  Together with MYO6, required for autophagosomal delivery of endocytic cargo, the maturation of autophagosomes and their fusion with lysosomes (PubMed:23023224).  MYO6 links TOM1 with autophagy receptors, such as TAX1BP1; CALCOCO2/NDP52 and OPTN (PubMed:31371777).  Binds to polyubiquitinated proteins via its GAT domain (PubMed:14563850).  In a complex with TOLLIP, recruits ubiquitin-conjugated proteins onto early endosomes (PubMed:15047686).  The Tom1-Tollip complex may regulate endosomal trafficking by linking polyubiquitinated proteins to clathrin (PubMed:14563850, PubMed:15047686).  Mediates clathrin recruitment to early endosomes by ZFYVE16 (PubMed:15657082).  Modulates binding of TOLLIP to phosphatidylinositol 3-phosphate (PtdIns(3)P) via binding competition; the association with TOLLIP may favor the release of TOLLIP from endosomal membranes, allowing TOLLIP to commit to cargo trafficking (PubMed:26320582).  Acts as a phosphatidylinositol 5-phosphate (PtdIns(5)P) effector by binding to PtdIns(5)P, thereby regulating endosomal maturation (PubMed:25588840).  PtdIns(5)P-dependent recruitment to signaling endosomes may block endosomal maturation (PubMed:25588840).  Also inhibits Toll-like receptor (TLR) signaling and participates in immune receptor recycling (PubMed:15047686, PubMed:26320582).
What are the official names of this protein?
Target of Myb1 membrane trafficking protein, Target of Myb protein 1.
What is the protein family that this protein belongs to?
Belongs to the TOM1 family.
Protein: RS4_BREBN
Sequence: MSRYTGPRHKLARRLGISLDGTGKDIKRNFPPGQHGHNNRRKLSEYGIQLQEKQKLRHMFGLNEKQFRRTFDNASKMAGVVGENFMKLLESRLDNLVYRMGFAPTRPAARQLVNHGHFLVNGKKVNIPSYRVQPGDVISIREKSRGLQLIKDALEGRTFLPNYVTFNDAAAEGTFTRLPDREEMPAEINEVLIVEFYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: MED6_HUMAN
Sequence: MAAVDIRDNLLGISWVDSSWIPILNSGSVLDYFSERSNPFYDRTCNNEVVKMQRLTLEHLNQMVGIEYILLHAQEPILFIIRKQQRQSPAQVIPLADYYIIAGVIYQAPDLGSVINSRVLTAVHGIQSAFDEAMSYCRYHPSKGYWWHFKDHEEQDKVRPKAKRKEEPSSIFQRQRVDALLLDLRQKFPPKFVQLKPGEKPVPVDQTKKEAEPIPETVKPEEKETTKNVQQTVSAKGPPEKRMRLQ
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 6, Activator-recruited cofactor 33 kDa component, ARC33, Mediator complex subunit 6, hMed6, Renal carcinoma antigen NY-REN-28.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 6 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SODM2_HALME
Sequence: GYVNGLNAAEETLRENRSSGDMDGSAAAMRSVSHNGCGHYLHHLFWRCMTPNGGGGEPTGDLRDRIESDFGSYEGWEAEFREAASWPAGGWALLVYDPVTKQLRNLAVQKHNDGALWSAHPILALDVWEHSYYFQYGPDRGGFVDA
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn] 2.
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: FANCG_MOUSE
Sequence: MSSQVIPALPKTFSSSLDLWREKNDQLVRQAKQLTRDSRPSLRRQQSAQDTLEGLRELLLTLQGLPAAVPALPLELTVLCNCIILRASLVQAFTEDLTQDLQRGLERVLEAQHHLEPKSQQGLKELWHSVLSASSLPPELLPALHCLASLQAVFWMSTDHLEDLTLLLQTLNGSQTQSSEDLLLLLKSWSPPAEESPAPLILQDAESLRDVLLTAFACRQGFQELITGSLPHAQSNLHEAASGLCPPSVLVQVYTALGACLRKMGNPQRALLYLTEALKVGTTCALPLLEASRVYRQLGDRAAELESLELLVEALSATHSSETFKSLIEVELLLPQPDPASPLHCGTQSQAKHLLASRCLQTGRAEDAAEHYLDLLAMLLGGSETRFSPPTSSLGPCIPELCLEAAAALIQAGRALDALTVCEELLNRTSSLLPKMSSLWENARKRAKELPCCPVWVSATHLLQGQAWSQLKAQKEALSEFSQCLELLFRTLPEDKEQGSDCEQKCRSDVALKQLRVAALISRGLEWVASGQDTKALSDFLLSVQICPGNRDGSFYLLQTLKRLDRKNEASAFWREAHSQLPLEDAAGSLPLYLETCLSWIHPPNREAFLEEFGTSVLESCVL
What is the function of this protein?
DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function.  May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability.  Candidate tumor suppressor gene (By similarity).
What are the official names of this protein?
Fanconi anemia group G protein homolog, Protein FACG.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSBI_DRANE
Sequence: MLTLKLFVYTVVIFFVSLFIFGFLSNDPGRNPGREE
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.8 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: Y3413_ALIFM
Sequence: MRIFSETEIRIIGCLIEKEITTPEQYPLTLNALTTACNQKSNRDPVTSLTDSDVLDSVNALIQERIITDETRGNSRVAKYQHRFCNTEFGSLKLSKQELAVLCVLFLRGPQTPGELRTRTQRLCEFDNVAQVENVLNGLSADEHSPKVIKLAKEPGKREARFAHLFCGEVSQATATVQQAPSESHDNERIVALESDVADLKLEVEELKKLINNLLDK
What are the official names of this protein?
UPF0502 protein VFMJ11_A0613.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: ATPD_ZYMMO
Sequence: MEISGSIQASLGGRYALALFEVAQEKGQIDTVAASLGKFDEAFAQARELRLLANNQIFSRKHVEKAIAALVPVLAIDDLTAKFLNLLAAKGRLGAFPEIASAYRQYVADLRSEKVADVITAHPLSDEQKSTLTARLKEQLKADVQINATVDPSILGGMIVRLGSRQIDGSIRSKLHMLAQAMKG
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS16_LEPIC
Sequence: MVKLRLQRTGTKHDPHYRIVAADSRSPRDGKFVDIVGHYHPAQIKEQTTFNKEKILTWLKNGAQPTGTVLNLFKNAGIWAEYKTTLKK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: RS12_METAR
Sequence: MGIGKFACRKLVHDRKLYRWSDRDYARRVLRLDEKADPLEGAPQAKGIVLEKVGVEAKQPNSAIRKCIRIQLIKNGRQITAFCPGDGAINFIDEHDEVTIEGIGGRMGGSYGDIPGVRFRVFKVNDVSLEEMVAGKRDKPLR
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: T1098_CONAA
Sequence: CCQLFVWCC
What is the function of this protein?
Probable toxin that inhibits ion channels.
What are the official names of this protein?
Conotoxin Am1099.
What are the subcellular locations of this protein?
Secreted.
Protein: URT2_DESRO
Sequence: MVNTMKTKLLCVLLLCGAVFSLPRQETYRQLARGSRAYGVACRDEKTQMIYQQQESWLRPEVRSKRVEHCRCDRGLAQCHTVPVKSCSELRCFNGGTCWQAASFSDFVCQCPKGYTGKQCEVDTHATCYKDQGVTYRGTWSTSESGAQCINWNSNLLTRRTYNGRRSDAITLGLGNHNYCRNPDNNSKPWCYVIKASKFILEFCSVPVCSKATCGLRKYKEPQLHSTGGLFTDITSHPWQAAIFAQNRRSSGERFLCGGILISSCWVLTAAHCFQERYPPQHLRVVLGRTYRVKPGKEEQTFEVEKCIVHEEFDDDTYNNDIALLQLKSGSPQCAQESDSVRAICLPEANLQLPDWTECELSGYGKHKSSSPFYSEQLKEGHVRLYPSSRCTSKFLFNKTVTNNMLCAGDTRSGEIYPNVHDACQGDSGGPLVCMNDNHMTLLGIISWGVGCGEKDIPGVYTKVTNYLGWIRDNMRP
What is the function of this protein?
Probably essential to support the feeding habits of this exclusively haematophagous animal.  Probable potent thrombolytic agent.
What are the official names of this protein?
Salivary plasminogen activator alpha 2, BAT-PA, DSPA alpha-2, T-plasminogen activator.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS16_ACIB5
Sequence: MVVIRLARGGAKKRPFYQIVVTDSRNARDGRFIERIGFFNPTAQGQAEKLRLDADRFAHWVSQGAQPSERVASLAAQAKKATA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: TRMY_AERPE
Sequence: MSLYVVISPTGRTDGNIPARGYAGPSGRLDVIARAYNAILEPNATLAALLMGGPLPPRLLIAPLSCKDIVRSERSFMIEASRALRGRRSCFTVNDEGVEALASLLRRFKPRILLAEKGGDISSHWGEMCSSSPTFIAGSHLDPPHGLIKHLERSLGGFLRVSVGPLSLHTDHVFLLVSALRLPMHATSIEHH
What is the function of this protein?
Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs.
What are the official names of this protein?
tRNA (pseudouridine(54)-N(1))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. TrmY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_ECO8A
Sequence: MQVSVETTQGLGRRVTITIAADSIETAVKSELVNVAKKVRIDGFRKGKVPMNIVAQRYGASVRQDVLGDLMSRNFIDAIIKEKINPAGAPTYVPGEYKLGEDFTYSVEFEVYPEVELQGLEAIEVEKPIVEVTDADVDGMLDTLRKQQATWKEKDGAVEAEDRVTIDFTGSVDGEEFEGGKASDFVLAMGQGRMIPGFEDGIKGHKAGEEFTIDVTFPEEYHAENLKGKAAKFAINLKKVEERELPELTAEFIKRFGVEDGSVEGLRAEVRKNMERELKSAIRNRVKSQAIEGLVKANDIDVPAALIDSEIDVLRRQAAQRFGGNEKQALELPRELFEEQAKRRVVVGLLLGEVIRTNELKADEERVKGLIEEMASAYEDPKEVIEFYSKNKELMDNMRNVALEEQAVEAVLAKAKVTEKETTFNELMNQQA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
Protein: RS11_META3
Sequence: MSEKWGVIHIYASYNNTIIHVTDITGAETIAKISGGMIVKNQKDESSPYAAMQGAFKIADMIREKGIDKVHIKVRATGGSKSKNPGPGAQAAIRALARAGIKIGRIEDATPIPHDGTTPKKGNR
What is the function of this protein?
Located on the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: MRAY_BORPD
Sequence: MLLEIARWLSDDVRAIGVLEYITMRAVLACATALLIGLVAGPRVIRKLTEMKIGQAVRAYGPESHLVKTGTPTMGGALILIAVAISTLLWADWTNRFVWVVLLVTFGFGWIGWMDDYRKVVYRDPEGMPARQKFFWQATIGLVAAVYLAFAVSAPANTELWPLFKAWVSSGFAMPLPTRADLIVPFFKSVSYPLGVLGFVALTWAVIVGTSNAVNLTDGLDGLAIMPTVMVGSALGIFAYVVGRVDYSKYLLFPYIPGAAELMVLCAAIAGAGLAFLWFNAYPAQVFMGDVGALALGGALGTIAVIVRQEIVLFIMGGVFVVETLSVMMQVTWFKYTKRKYGQGRRIFRMAPLHHHFEVGGWKETQVVVRFWIISMMLVLIGLSTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y90_SIRV1
Sequence: MQVEEMQEKVINLAQKYTNQKRFFRLIRKSNIAEKIIKEISEFYGIREDNIELFDNEIEFMFKKESVKLILKKQGNKLKIENIEMTKSIS
What are the official names of this protein?
Uncharacterized protein 90.
Protein: TTCA_ACTP2
Sequence: MNQDTQSANTQQEKKIAYNFNKLQKRLRRNVGNAIADFNMIEDGDKVMVCLSGGKDSYTLLDILLNLKLSAPIHFDIVAVNLDQKQPGFPEHILPEYLESIGVEYKIVEENTYGIVKEKIPEGKTTCSLCSRLRRGILYRTATELGATKIALGHHRDDMLETLFLNMFYGGKLKSMPPKLISDDGKQIVIRPLAYCKEKDIEKYSQAKQFPIIPCNLCGSQPNLQRQVVKEMLQTWDRQYPGRIETMFSAMQNITLSHLCDPSLFDFKGLKRGQVLDGVEGDIAFDKAEIPNQPLIQDEDEQTTDYGENGMIQFKQVQ
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR5_BREBN
Sequence: MSEAYKQAGVDIDAGNEAVERMKKHVKRTFRPEVMTDLGGFGALFRLDTKKYEKPILVSGTDGVGTKLKLAFAMDKHDTIGIDAVAMCVNDVVVQGAEPLFFLDYLAVDKVIPEKIEAIVKGIAEGCSQSGCSLIGGETAEMPGMYAEGEYDIAGFTVGVVDESKMITGASVAAGDVLIGLASSGVHSNGFSLVRKVLLADKGMSLHDHVDVLGKKLGEELLTPTRIYVKQVLSVLESHEVKALVHITGGGFTENIPRVLPEGMQAVINVGSWPVLPIFELVQGAGNISYPDMYKTFNMGIGMMLVVKPEDAVSVMEKLQELGEQAYLIGNIQAGERKVVYNGVEW
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_AERHH
Sequence: MQLNSTEIAELIKQRIAQFDIKSEARNEGTIVSVSDGIIRIHGLADAMQGEMIELPGNRYALALNLERDSVGAVIMGSYDGLSEGMKVKGTGRILEVPVGRGLLGRVLNTLGQPIDGKGPIDNDGFSPIEVIAPGVIERKSVDQPVQTGLKAIDAMIPIGRGQRELIIGDRQVGKTAIAIDTIINQKDSGIKCVYVAIGQKASTIANVVRKLEEHGALANTIVVVASASEAAALQYLAPYAGCSMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVNAEYVEKFTNGAVKGQTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLTSQLFNSGIRPAVDPGISVSRVGGAAQTKIVKKLSGGIRTALAQYRELAAFAQFSSDLDDATRKQLDHGQKVTELMKQKQYSPLSVAHQSLVLFAAEKGYLSDVELNKIVDFEAALLSYANTQHAELMAEINAKADYNDAIVGKLTALLDDFKATQTW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RB3GP_DROME
Sequence: MAEEIDDNEFYRENFSADSDWEVFNAQLGEILQKWDVSSDSETRNLKSEEIFSCNWKVEREKLDMLRNGIEVEYHQAILEDEELVRAEAKEITCLQRTSCHHDLMSTGNSFGPPIRSSQELHILARIYGLRRFIVLHPVNPTLNYMRSTSEFNFFLSAVAVVSAEVQSLVPIFVQIYDPKWNYYTGVALAPALRTNFRLIGLEKAPPECRFLMGLLTLFREKVPTSYTQAAMISVCTTYALDTMRIRMPMYVPFDHGLSSEDIVVDGEVSHLEVQQFCALPHGYKPESRTEIYLVYTWPELSEHVAFDSEQRSDFVPAKAPLGKIYLSVEASSYLSCCLRDYQSVAEVTRSLESFVGRNFSGTSSGAEAASNPLDRITEHKLTKRRERSFELPSQAGLTKRLPGPMTESELSELLAYLFPDMHPEMALFPYAKKNFTDKFDPMRIKSAVPDSLVCRLSCLLATCHAHLGSVEGMAQVWAAFTRQLRLLWDNSLMVPGISAGFPDTRTCLLHQKLQMLNVCVERRVQREANSKRKSEGMVGKASSEEEEDEDDDEGEFFDCDDLTAGAGSPTKAVLSLKPEGRLRRLNNERLLEEPDEYLYIPDTQEPVPKTEDQLQDDAEVMLKLGPGSGLTTQMMCTSLLSDMEAFKAANPRGIMEDFIRWYSPKDWEEVTDELGQVKHQLSIRMTTEGNTWQKVWEQAQAVPVSRQKRLFDDTNEALKVLHYLETRKMHEIYNLTVIPLLHSAILKLADILSNAELEDLFSSQIEKLLSDLCRLSRSHSDELPSIKPLLDDLAELERRFYQFKCFERLSGYPKRSSLQQVKLQFEEILRNDNCCTIVNRRLTAAGDGTLYDILIPKLEEDMADRLISKDYIIRLDGDTKTTEKGLYLGPQFMRAIVTGEKLRLCGAFTESTAFV
What is the function of this protein?
Catalytic subunit of the Rab3 GTPase-activating (Rab3GAP) complex composed of Rab3-GAP and Rab3GAP1, which has both GTPase-activating protein (GAP) activity towards Rab3, and guanine nucleotide exchange factor (GEF) activity towards Rab18 (Probable).  As part of the Rab3GAP complex, required for the rapid induction and sustained expression of synaptic homeostasis at the neuromuscular junction (NMJ) (Probable).  Also participates in the regulation of autophagy in tissues such as larval fat cells and adult muscles (Probable).  The Rab3GAP complex, acts as a GAP for Rab3 by converting active Rab3-GTP to the inactive form Rab3-GDP (By similarity).  At the neuromuscular junction (NMJ), forms a presynaptic signaling mechanism with Rab3 that regulates progression of synaptic homeostasis at a late stage of vesicle release (Probable).  Within this mechanism Rab3-GTP acts, directly or indirectly, to inhibit the progression of synaptic homeostasis, and Rab3-GAP functions to inactivate this action of Rab3-GTP (Probable).  The Rab3GAP complex, acts as a GEF for Rab18 by promoting the conversion of inactive Rab18-GDP to the active form Rab18-GTP (By similarity).  Regulates autophagy as part of a Rab3GAP-Rab18 module (PubMed:32248620).  Once Rab18 is activated by the GEF Rab3GAP complex, the Rab3GAP-Rab18 module localizes to autophagosomes, and regulates autolysosome formation and maturation together with the Rab18 interacting effector, the PI3K/Vps34 Complex I (PubMed:32248620).
What are the official names of this protein?
Rab3 GTPase-activating protein catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the Rab3-GAP catalytic subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS4_THEON
Sequence: MRIYPAIDLMGGKAVRLYRGQKEKVKVYGDPVEIASRFTELVDKIHVVDLDGAFTGKPQNLDVVKEIIEETGLKVQVGGGFRSYESIAKAYEIGAENVIIGTKAFDLEFLEKITDNFDGITVSLDARGGKIAVKGWLEESSLKVGEAYEMLREYVDRFIYTSIERDGTLTGIESIERFWKDEEFIYAGGVSSVDDVLKLRRVGFSGAIVGKALYESEVSLKELLEVLEC
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AOG_PHAAN
Sequence: MKTLTPSVEIFFFPYVGGGHQIPMIDAARMFASHGASSTILATPSTTPLFQKCITRDQKFGLPISIHTLSADVPQSDISVGPFLDTSALLEPLRQLLLQRRPHCIVVDMFHRWSGDVVYELGIPRTLFNGIGCFALCVQENLRHVAFKSVSTDSEPFLVPNIPDRIEMTMSQLPPFLRNPSGIPERWRGMKQLEEKSFGTLINSFYDLEPAYADLIKSKWGNKAWIVGPVSFCNRSKEDKTERGKPPTIDEQNCLNWLNSKKPSSVLYASFGSLARLPPEQLKEIAYGLEASEQSFIWVVGNILHNPSENKENGSGNWLPEGFEQRMKETGKGLVLRGWAPQLLILEHAAIKGFMTHCGWNSTLEGVSAGVPMITWPLTAEQFSNEKLITEVLKTGVQVGNREWWPWNAEWKGLVGREKVEVAVRKLMVESVEADEMRRRAKDIAGKAARAVEEGGTSYADVEALIQELQARTCANQG
What is the function of this protein?
Glucosyltransferase involved in the catabolism of abscisic acid (ABA).  Adds a glucosyl group at the C-1 position of ABA; (S)-2-trans-abscisate is a better substrate than the natural (+)-S-abscisate or its enantiomer (-)-R-abscisate.  No activity with (-)-phaseic acid (PA), methylated-ABA or with other hormones such as jasmonate, zeatin, auxin (IAA) or gibberellin A3 (GA3).
What are the official names of this protein?
Abscisate beta-glucosyltransferase, ABA-glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: FAR3_HEMMO
Sequence: GPSAFLRL
What is the function of this protein?
FMRFamides and FMRFamide-like peptides are neuropeptides.
What are the official names of this protein?
Extended FMRFamide-3, FMRFa-3.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRF amide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RSMG_DEHMB
Sequence: MNELVYGLSALGISLNSVQLGQFETYYQELVDYNSRINLTAITEYKDVQIKHFLDSVSLVLAGIKGDEKLLDVGSGAGFPGLPLKILFPAIQLGLLEATQKKARFLSEITVKLGLSGVEIISQRAEDTAQNPLYRQKYSLVTSRAVADMATLAELTLPFCAIGGRVIAPKKGDIEEEMDRAATAVKKMGGRVFKVIKVELPGLEDGRKLVLLEKISNTPALYPRRAGIPAKTPLI
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HCAE_ECOHS
Sequence: MTTPSDLNIYQLIDTQNGRVTPRIYTDPDIYQLELERIFGRCWLFLAHESQIPKPGDFFNTYMGEDAVVVVRQKDGSIKAFLNQCRHRAMRVSYADCGNTRAFTCPYHGWSYGINGELIDVPLEPRAYPQGLCKSHWGLNEVPCVESYKGLIFGNWDTSAPGLRDYLGDIAWYLDGMLDRREGGTEIVGGVQKWVINCNWKFPAEQFASDQYHALFSHASAVQVLGAKDDGSDKRLGDGQTARPVWETAKDALQFGQDGHGSGFFFTEKPDANVWVDGAVSSYYRETYAEAEQRLGEVRALRLAGHNNIFPTLSWLNGTATLRVWHPRSPDQVEVWAFCITDKAASDEVKAAFENSATRAFGPAGFLEQDDSENWCEIQKLLKGHRARNSKLCLEMGLGQEKRRDDGIPGITNYIFSETAARGMYQRWADLLSSESWQEVLDKTAAYQQEVMK
What is the function of this protein?
Part of the multicomponent 3-phenylpropionate dioxygenase.  Converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid-dihydrodiol (CI-dihydrodiol), respectively.
What are the official names of this protein?
3-phenylpropionate/cinnamic acid dioxygenase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.