PharMolix/UniProtQA huggingface dataset:
Protein: MBCA_MYCTU
Sequence: MGVNVLASTVSGAIERLGLTYEEVGDIVDASPRSVARWTAGQVVPQRLNKQRLIELAYVADALAEVLPRDQANVWMFSPNRLLEHRKPADLVRDGEYQRVLALIDAMAEGVFV
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system (PubMed:30315706, PubMed:30792174).  Neutralizes the activity of cognate toxin MbcT by blocking access to the toxin active site (PubMed:30792174).
What are the official names of this protein?
Mycobacterial cidal antitoxin MbcA, Antitoxin Xre, ucAT8 antitoxin.
What is the protein family that this protein belongs to?
Belongs to the MbcA/ParS/Xre antitoxin family.
Protein: DEF_KARMG
Sequence: MILPIIIYGNSFLRKKCIEIDKSYKDINFLINNMYDTMYQAKGIGLSAPQIGLSIRLFIIEYNNFLKQKFKKVFINPIIIKKYGYNLISKEGCLSIPNIIENIKRKNNIIIEYYDENWKKYKQHFNGLLSIIIQHEYDHIEGKLFIDNIFILKNILIKKNFNLNYNLYKLYKLSKLYKFYLIYRSRYRI
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: PYRB_DESAP
Sequence: MPVRHLLGLADMPAAEINEFLENALPMKQIISRDIKKVPTLRGKTVVTLFYEPSTRTRMSFELAAKYLSADTVNVSASASSATKGESLADTARTIAALGADLVVLRHPCAGAPHLLARMIDVPVVNAGDGMHEHPTQALLDLFTLREKRPDLEGLKLVIIGDILHSRVARSNIWALTRFGVDVHLVAPPTLLPAGIAAFGVTVHDRPEDALPDAGAVMVLRLQRERQQEGLIPDVREYARLYGLNSERLALTRPDAIVMHPGPMNRGIEIAHTVADGTRAVITDQVTNGVAVRMAVLYLLMLGRVD
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: RRF_CERS1
Sequence: MSQDDLEIDLDAIQRRMDGAMHALRTEFGSLRTGRASASILEPIHVDAYGQQTPLNQLGTINVPEPRMVVINVWDKGMISKVERAIRDSGIGINPVVDGPIIRLPIPELNEERRKELSKVAAHYAEQARVAIRNVRRDGMDQIKKAKSAGMAEDDQKMWSDEVQALTDKAIAAVDKALEEKQKEIMQV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSB_RICCN
Sequence: MAGSLNKVILIGNVGRDPEMRTTGEGKKIINLSLATTETWKDRITSERKERTEWHRVVIFSEGLVSVVERYVTKGSKLYIEGSLQTRKWNDNSGQEKYTTEVVLQNFNSQLILLDSKNSNNHNQDSGHSEYKHPETKNHSFDHSDLDDEIPF
What is the function of this protein?
Plays an important role in DNA replication, recombination and repair.  Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
What are the official names of this protein?
Single-stranded DNA-binding protein, SSB.
Protein: ACRR_SHIFL
Sequence: MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE
What is the function of this protein?
Potential regulator protein for the acrAB genes.
What are the official names of this protein?
HTH-type transcriptional regulator AcrR, Potential acrAB operon repressor.
Protein: RL18_THEPD
Sequence: MARGARYRVPLKRRREGKTNYYKRRKLIISGKPRLVVRVLSRTAIVQIAKATPKGDVVIASAHSNELKKYGWKGYRRNTPALYLLGFLAAKKALKQGVTEAIVDIGLHRPVKASRVFAAVKGALDAGLKIPVGDGVLPEDDRVRGEHIANYAKMLKESNPELFKLRFSGYLSAGLDPESLPEHFDSVKQKIEEALQ
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: GCSPA_MAGSA
Sequence: MRYLPLTEADRRAMLDVIGAKSVDDLFRDVPPSARLAGPLPLPSHQGEMEVERAFTRMAGKNLSAGCAPFFIGAGVYRHHVPAAVDQLLLRGEFLTAYTPYQPEVSQGTLQMLFEFQSQVATITGMDVANASMYDGATACAEAAIMACRITKRNRVIVSGGVHPHYAETLETSLRFTEMEADVLPPDPLGMEDMIGRVDSKTACVVVQNPGFFGTVRDLRPLAALCHEAGALLVVMVAEPTSLGLIESPGAMGADIVVCEGQSLGMGLNFGGPGLGLFATRDKYVRQMPGRLVGQTADVDGRRGWVLTLSTREQHIRREKATSNICTNSGLCALAFSIHLTMLGGTGFGRLAELNHLAATRLEQKLRAVKGLRVLPQSYYNEFAVHLGDDADAAAVVDALADKGILAGVPASRFYPTWPELKPVLILAATETNTEDDMDRLVAGLQEVL
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: CSN_ASPFM
Sequence: MRLSEILTVALVTGATAYNLPNNLKQIYDKHKGKCSKVLAKGFTNGDASQGKSFSYCGDIPGAIFISSSKGYTNMDIDCDGANNSAGKCANDPSGQGETAFKSDVKKFGISDLDANIHPYVVFGNEDHSPKFKPQSHGMQPLSVMAVVCNGQLHYGIWGDTNGGVSTGEASISLADLCFPNEHLDGNHGHDPNDVLFIGFTSKDAVPGATAKWKAKNAKEFEDSIKSIGDKLVAGLKA
What is the function of this protein?
Chitosanase catalyzing the endo-type cleavage of chitosan, the deacylated form of chitin.  Chitosanase may be crucial in the degradation of the deacetylated portion of chitin in the fungal cell wall.  Chitoolisaccharides produced by the hydrolysis of partially N-acetylated chitosan are known to have many biological activities, including antibacterial activity, immune-enhancing effects, and elicitor activity.  The chitosans with higher degrees of deacetylation were shown to be the better substrates.  Chitodimer, chitotrimer, and chitotetramer are the major products but monoacetyl chitodimer, monoacetyl chitotrimer, and monoacetyl chitotetramer are also produced.
What are the official names of this protein?
Endo-chitosanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 75 family.
What are the subcellular locations of this protein?
Secreted.
Protein: NU2M_BALMU
Sequence: MNPSIFIILLTTLILGTMMVITSSHWLLAWIGFEMNMMAFIPIMMKNPSPRATEASTKYLLTQATASALLMMAVIINLMYSGQWTITKLFNPTASTLMTVALAIKLGLAPFHFWVPEVTQGIPLTTGLILLTWQKLAPLSILYQISPSINLYLMLTMSLLSILVGGWGGLNQTQLRKIMAYSSIAHMGWMTTILPYNPTLTLLNLLIYITMTFTMFMLFIQNSTTTTLSLSQTWNKTPIITTLTMLTLLSMGGLPPLSGFMPKWMIIQELTKNDILIMPTFMAITALLNLYFYMRLTYSTALTLFPSTNNMKMKWQFSPTKRAPLLPTAIVISTMLLPLTPMLSILL
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RLME_CUPNH
Sequence: MAKNKFNHSWLHDHINDPYVKMAQREGYRARAAYKLKEIDEQDKLIRPGQVIVDLGAAPGSWSQYARNKLADSPRAKDGRIDGAVVAIDLLPMEPVADVTFIQGDFREESVFRELESVVLDASGGNKIDLVLSDMAPNLSGVAFADAARIEYLCDLALEFAQAHLKPEGALLVKCFHGSGYSQIVEKFKRHFKVVAKRKPKASRDKSSETFILGRYLKAVD
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDK14_XENLA
Sequence: MCDMIESQPAQKIGKMKKLRRTLSDSFSRIALKKDENAIDEICVTKMSTRNCQGIDSVIKHLDPIPEDKKVRVQRTQSSFDPFEKTSNQPTSPKFGKADSYEKLEKLGEGSYATVFKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLNPENVKLFLFQLLRGLSYIHQGHILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTDYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLILGTPIEETWPAVHSLPHFEPERFTLYGPKNLRQAWNKLSYVNHAEDLASKLLQCFPKNRLSAQAALNHDYFSDLPPRLWELSDMSSIFTVPNVKLQPEAGESMRVFGKNNSFSKSLSNSKH
What is the function of this protein?
Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin.  Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of lrp6, leading to the activation of the Wnt signaling pathway (By similarity).
What are the official names of this protein?
Cyclin-dependent kinase 14, Cell division protein kinase 14.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Note=Recruited to the cell membrane by CCNY.
Protein: RNC_VIBCH
Sequence: MTPPMNKLTSKLGYTFKETELLNLALTHRSANGKHNERLEFLGDSILSFVIADELYRRFPKVNEGDMSRMRATLVRGNTLAELGREFDLGDYLKLGPGELKSGGFRRDSILADAVEAIIGAIYLDSDLETARSIVLEWYHGRLEEIKPGASQKDPKTRLQEFLQGRRKPLPVYTVTNIKGEAHNQEFTVACEVAGMDTPVIGKGTSRRKAEQAAAETALEQLTNG
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYR6_MICDP
Sequence: MAPLTEASRLGVRPFADSDKVELRFVKTAEEVRSVIWSAYRQVLGNEHLFESERLSSAESLLQQAQISVRDFVRAIAQSELYRQKFFYSNSQVRFIELNYKHLLGRAPYDESEIAYHVDIYTSQGYEAEINSYIDSVEYQQNFGDSIVPYYRGYQTTVGQKTAGFPRFFQLYRGYANTDRAQNKSKGQLTWDLAKNLVSPIYPADAGSLTGVSTGNRGGNTYRIRTTQAASPNSPRIRQSISRVVVPFDQLSNLLQQLNRQGRKVISIALS
What is the function of this protein?
Rod linker protein, associated with phycocyanin.  Linker polypeptides determine the state of aggregation and the location of the disk-shaped phycobiliprotein units within the phycobilisome and modulate their spectroscopic properties in order to mediate a directed and optimal energy transfer.
What are the official names of this protein?
Phycobilisome 30.8 kDa linker polypeptide, phycocyanin-associated, rod, L-30.8/R.
What is the protein family that this protein belongs to?
Belongs to the phycobilisome linker protein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=Associated with phycocyanin.
Protein: PLAS_CUCSA
Sequence: IEILLGGDDGSLAFVPNNFTVASGEKITFKNNAGFPHNVVFDEDEIPSGVDSGKISMNEEDLLBAPGZVYZVZLTZKGSYSFYCSPHQGAGMVGKVTVN
What is the function of this protein?
Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I.
What are the official names of this protein?
Plastocyanin.
What is the protein family that this protein belongs to?
Belongs to the plastocyanin family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Lumenal side. Note=Loosely bound to the inner thylakoid membrane surface in chloroplasts.
Protein: FLHD_EDWI9
Sequence: MSTSEILKHIYDINLSYLLLAQRLIHDDKASAMFRLGIDADMAETLVQLTLPQMVKLAETNQLVCQFRFEDHQTIQRLTQESRVDDLQQIHTGILLSSHLLQQLSADGNDSGKRG
What is the function of this protein?
Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region.  Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes.  Also regulates genes whose products function in a variety of physiological pathways.
What are the official names of this protein?
Flagellar transcriptional regulator FlhD.
What is the protein family that this protein belongs to?
Belongs to the FlhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_SALCH
Sequence: MAKLHDYYKDEVVNKLMTEFNYNSVMQVPRVEKITLNMGVGEAIADKKLLDNAAADLTAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRGLDITITTTAKSDEEGRALLAAFDFPFRK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: TERL_BPLP2
Sequence: MYYLNKMLEYNKENGIIINKYIRKTIQKQIRIHNKYIYRYDRVTQAIEWIEDNFYLTTGNLMKIELLPTQRWWYELMLGYDMIDEKGVQVNLINEIFLNLGRGSGKSSLMATRVLNWMILGGQYGGESLVIAYDNTQARHVFDQVRNQTEASDTLRVYNENKIFKSTKQGLEFTSFKTTFKKQTNDTLRAQGGNSSLNIFDEVHTYGEDITESVNKGSRQKQDNWQSIYITSGGLKRDGLYDKLVERFKSEEEFYNDRSFGLLYMLENHEQVKDKKNWTMALPLIGSVPKWSGVIEEYELAQGDPALQNKFLAFNMGLPMQDTAYYFTPQDTKLTDFNLSVFNKNRTYVGIDLSLIGDLTAVSFVCELEGKTYSHTLTFSVRSQYEQLDTEQQELWTEFVDRGELILLDTEYINVNDLIPHINDFRTKTGCRLRKIGYDPARYEILKGLIERYFFDKDGDNQRAIRQGFSMNDYIKLLKSKLAENKLIHNQKVMQWALNNTAVKIGQSGDYMYTKKLEKDKIDPTVALTMALEMAVSDEV
What is the function of this protein?
Probable terminase large subunit (PubMed:24027307).  The terminase large subunit acts as an ATP driven molecular motor necessary for viral DNA translocation into empty capsids and as an endonuclease that cuts the viral genome to initiate and to end a packaging reaction (By similarity).  The terminase lies at a unique vertex of the procapsid and is composed of two subunits, a small terminase subunit involved in viral DNA recognition (packaging sequence), and a large terminase subunit possessing endonucleolytic and ATPase activities (By similarity).  Both terminase subunits heterooligomerize and are docked on the portal protein to form the packaging machine (By similarity).  The terminase large subunit exhibits endonuclease activity and cleaves the viral genome concatemer (By similarity).
What are the official names of this protein?
Terminase large subunit, DNA-packaging protein, Gene product 2, gp2.
What is the protein family that this protein belongs to?
Belongs to the skunavirus terminase large subunit family.
Protein: LGT_ECO57
Sequence: MTSSYLHFPEFDPVIFSIGPVALHWYGLMYLVGFIFAMWLATRRANRPGSGWTKNEVENLLYAGFLGVFLGGRIGYVLFYNFPQFMADPLYLFRVWDGGMSFHGGLIGVIVVMIIFARRTKRSFFQVSDFIAPLIPFGLGAGRLGNFINGELWGRVDPNFPFAMLFPGSRTEDILLLQTNPQWQSIFDTYGVLPRHPSQLYELLLEGVVLFIILNLYIRKPRPMGAVSGLFLIGYGAFRIIVEFFRQPDAQFTGAWVQYISMGQILSIPMIVAGVIMMVWAYRRSPQQHVS
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: END8_SALCH
Sequence: MPEGPEIRRAADNLEAAIKGKPLTDVWFAFAQLKPYESQLTGQLVTRIETRGKALLTHFSNGLTLYSHNQLYGVWRVIDTGEIPQTTRILRVRLQTADKTILLYSASDIEMLTAEQLTTHPFLQRVGPDVLNARLTPEEVKARLLSPRFRNRQFSGLLLDQAFLAGLGNYLRVEILWQVGLTGQHKAKDLNEAQLNALSHVLLDIPRLSYTTRGQADENKHHGALFRFKVFHRDGEACERCGGIIEKTTLSSRPFYWCPHCQK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine.  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Endonuclease 8, DNA glycosylase/AP lyase Nei, DNA-(apurinic or apyrimidinic site) lyase Nei, Endonuclease VIII.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: G3PC3_ORYSJ
Sequence: MGKIKIGINGFGRIGRLVARVALQSEDVELVAVNDPFITTEYMTYMFKYDTVHGQWKHHEVKVKDSKTLIFGTKEVAVFGCRNPEEIPWAAAGAEYVVESTGVFTDKDKAAAHLKGGAKKVVISAPSKDAPMFVVGVNEKEYKSDVNIVSNASCTTNCLAPLAKVINDRFGIVEGLMTTVHAITATQKTVDGPSMKDWRGGRAASFNIIPSSTGAAKAVGKVLPALNGKLTGMAFRVPTVDVSVVDLTVRLEKPASYDQIKAAIKEEAEGKLKGILGYVEEDLVSTDFQGDSRSSIFDAKAGIALSDTFVKLVSWYDNEWGYSTRVIDLIRHMHSTN
What is the function of this protein?
Key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate.  Essential for the maintenance of cellular ATP levels and carbohydrate metabolism (By similarity).
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase 3, cytosolic.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_BORT9
Sequence: MIKKYEACFLFKSEELEYKAALEEVKKQLTVFNASDFAENSLGERALEYPIRKQLRGRYEIIEFKMDSENLKELEIQLKLIKNLLRHMILVKINKKVSVKKVKRRNFREFKDNRDIKEKESSEFNSNVDVKVD
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: CHEB_BORPA
Sequence: MKKIKVLCVDDSALVRGLMTEIINSHPDMEVVATAPDPLVARELIKKHNPDVLTLDVEMPRMDGLDFLEKLMRLRPMPVVMVSSLTERGGEITLRALELGAIDFVTKPKLGIRDGLIEYSEVIADKIRAASRARLRAPAPAGHAAPLRLRSPFASSEKLVIVGASTGGTEAIREVLQPLPADSPAILITQHMPAGFTRSFAQRLDALCAVTVREASDGERVLPGHVYLAPGGETHMRLGRSGANYVIGLQASEPVNRHRPSVDVLFHSAAEAAGGNAIGVILTGMGKDGAAGLLAMKRAGARTMAQDEASCVVFGMPREAIALGAADEVMPLADISERILTRLGDRGHRV
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRCA_MYCGA
Sequence: MNNKLTERQILILKAIINEYISTATAVGSKIILEKYFNNEVSSATIRNEMSVLEKEKYIEKPHTSAGRIPTIKGYQYYEANLAETKISERLKQKLMAILNKRYHSIDEVIEQSVEFINNVTNLPSVITKFKSYDLLKRMDLIKINNNTAIILIVSSSGEVIKKTIKYQNSIQYNDVSTCVQIFNDRLVDTPFIELKEKLTAIKEIVRTKVHEYEFVMQRIVNYIFDINEKSTINIKGTKKLVIHPEFHDHNKLSEILNLLENTSIWEQISFMQQKTGKSVITFGQDIGIEGISVASTLIETEQNKHQIAIVGPNRMEYGKIKGLLNILKEQVEKIDHLNLPLEEINKES
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: FPG_ECO81
Sequence: MPELPEVETSRRGIEPHLVGATILHAVVRNGRLRWPVSEEIYRLSDQPVLSVQRRAKYLLLELPEGWIIIHLGMSGSLRILPEELPPEKHDHVDLVMSNGKVLRYTDPRRFGAWLWTKELEGHNVLAHLGPEPLSDDFNGEYLHQKCAKKKTAIKPWLMDNKLVVGVGNIYASESLFAAGIHPDRLASSLSLAECELLARVIKAVLLRSIEQGGTTLKDFLQSDGKPGYFAQELQVYGRKGEPCRVCGTPIVATKHAQRATFYCRQCQK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: PUR7_CAMC5
Sequence: MQKRELIYEGKGKKMYATDDANLLIAEFKDDLTAFDAQKRGNEAGKGALNNKISTQIFKILKEKGIETDLVETISDTEQLVKKCEIIPLEVVVRNIATGSLTKRLAIKEGTVLPFPLVEFYFKNDELHDPLVTDEHCLVMGLVKSEKDLQTLRHLAREINSILFKFFEERKLKLVDFKIEFGMDKDGNILLADEISPDSCRFWDADTNEKLDKDRFRQDLGSVKVAYEEVLRRILS
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: CDC23_DICDI
Sequence: MSQIKIELIKSINDLNSRGLLLSSKWSSEQLNGLSPTILATPLTNEEQLSIISQPSISSPPIGSNEYYKYILAKNYFDLKEYRRCSDVLIDCNKYQLPIFLRSYATYLAIEKRREEDIIEQQAQQQQQQQQAQQQAQQAQQESQQNDKNNDTNNNNKTDQQQQQQQQQKIEQCQEFKQLFQFYKKLYIENKKDMDGFLLYFYSMLLKKQRDFTMARKVLIESVHKYPCNWSAWSDLSSLCSDSADIIMQLSLPDHFMKDFFLAHFKLELQQNNESLVIYQQLSRTLFTQSTYILAQTAIGNYNLRAYDIGEELFERLIELEPNRLENIDIYSNILYVRDKKASLSMLAHKAMKIEKYCPETCCIIGNYYSLKLEHDKAILYFQRALKLNDRYLSAWTLIGHEFLEIKNVSAAINAYRKAVDINPRDYRAWYGLGQTYQLLKLPLYSLYYFKKATTLRPYDPRMWCAAGGCYEFIERIPEAIKCYERAEENYDRERVAINKLAKLYQEIQNNEKAAFYYKKNLYYCDQEKIDGQEIIDALLFLANFYKNQNQTQSEQYCLRLLDYAGPEKEEAKSILREIHSKSKLSSKSKPK
What is the function of this protein?
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.
What are the official names of this protein?
Anaphase-promoting complex subunit 8, APC8, Cell division cycle protein 23 homolog.
What is the protein family that this protein belongs to?
Belongs to the APC8/CDC23 family.
What are the subcellular locations of this protein?
Nucleus.