PharMolix/UniProtQA huggingface dataset:
Protein: SYK_MYCTA
Sequence: MSAADTAEDLPEQFRIRRDKRARLLAQGRDPYPVAVPRTHTLAEVRAAHPDLPIDTATEDIVGVAGRVIFARNSGKLCFATLQDGDGTQLQVMISLDKVGQAALDAWKADVDLGDIVYVHGAVISSRRGELSVLADCWRIAAKSLRPLPVAHKEMSEESRVRQRYVDLIVRPEARAVARLRIAVVRAIRTALQRRGFLEVETPVLQTLAGGAAARPFATHSNALDIDLYLRIAPELFLKRCIVGGFDKVFELNRVFRNEGADSTHSPEFSMLETYQTYGTYDDSAVVTRELIQEVADEAIGTRQLPLPDGSVYDIDGEWATIQMYPSLSVALGEEITPQTTVDRLRGIADSLGLEKDPAIHDNRGFGHGKLIEELWERTVGKSLSAPTFVKDFPVQTTPLTRQHRSIPGVTEKWDLYLRGIELATGYSELSDPVVQRERFADQARAAAAGDDEAMVLDEDFLAALEYGMPPCTGTGMGIDRLLMSLTGLSIRETVLFPIVRPHSN
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPA_DESOH
Sequence: MTAFSFKKEDRLLKRYEFIEIFTSGKTVHSSCFLAGIKKNRKERIRLGITVSKKVGKAARRNRIKRHVREFFRLHRDNLSNCWDINVIAKKKAVNASPAELERSLAELFHKSSREFPSDRQ
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: AGN3_PAEDI
Sequence: MADLTPVQVLPADIGILNFANIGSDSLAECNRLLDKNHRDHHMFVRDTAGHNHIVHAVLAVLALGGSPQELRDRYDDGASMQRPLPPCDAELLEKLNDPEVFMATLSERAQYTTFLTFFERKMAERGWRSVLQEYLFARTPLADAMLGRLYEGAYHALIHLGYGIEFQSPAIIAEALGQAASHDDSGIAQLFRSAEEEAVFQYPTPRGTPLIELVHEVRANDQIRTAPRWSDYGNKMRDGIVGRACEPMSTLASQFQIFPNEADLERRTAEMIGVCAYMSGAAQRPGRKRKIDFFHMHALNSALFFTVLIRQQWIRLEDRVRMVERKARLDLAWYAVAGSAALDATAITDYSSPESDGLGWDELFAAVNKEHDDGHAAKFIRALKNGEMVSRRYEQGEWAEFFPMKGDMWLKLARMCQDTTKGMPSDLKWIPFTGFEQPWKRADLAEAGETNTAEKVRLY
What is the function of this protein?
Baeyer-Villiger oxidase; part of the gene cluster that mediates the biosynthesis of agnestins, dihydroxy-xanthone metabolites (PubMed:30746079).  The pathway begins with the assembly and cyclization of atrochrysone thioester by the non-reducing polyketide synthase Agnpks1 (PubMed:30746079).  The atrochrysone carboxyl ACP thioesterase AgnL7 then breaks the thioester bond and releases the atrochrysone carboxylic acid as the first enzyme-free intermediate (PubMed:30746079).  The decarboxylase AgnL1 then catalyzes the concerted decarboxylation-elimination required to convert atochrysone carboxylic acid into emodin anthrone, which is further oxidized to emodin by the anthrone oxygenase AgnL2 (PubMed:30746079).  Emodin then undergoes reduction catalyzed by the oxidoreductase AgnL4 to yield the dihydroquinone tautomer which is the substrate for reduction by the short chain dehydrogenase AgnL6 reduction to produce hydroxyketone, followed by AgnL8 dehydration and likely spontaneous autoxidation to chrysophanol (PubMed:30746079).  Baeyer-Villiger oxidation by the oxidase AgnL3 leads to monodictyphenone via cleavage of the C-10/C-10a bond of chrysophanol (PubMed:30746079).  Alternative cleavage at the C-4a/C-10 bond of chrysophanol leads also to the formation some cephalone F (PubMed:30746079).  Further conversion to agnestins A and B, requires reduction to dihydro-monodictyphenone, oxidation to agnestin C probably via an epoxide, and rearrangement to either agnestin A or agnestin B directly, although agnestin A or agnestin B can also interconvert (PubMed:30746079).  Within the cluster, AgnR1 is the only unassigned oxidoreductase present which could be involved in this conversion.  However, AgnR1 seems not to be involved in this step, and thus genes involved in the proposed oxidation/reduction may be located elsewhere on the genome (PubMed:30746079).  Further agnestin A derivatives are probably formed by spontaneous decarboxylations, dehydrations and methanolysis reactions (PubMed:30746079).
What are the official names of this protein?
Baeyer-Villiger oxidase AgnL3, Agnestins biosynthesis cluster protein L3.
What is the protein family that this protein belongs to?
Belongs to the questin oxidase family.
Protein: TLC3B_MOUSE
Sequence: MLTPMVAGGVVFPGLFLLSKNTLQRLPQLRWEEADAVIVSARLVSSVQAIMASTAGYIVSTSCKHIIDDQHWLSSAYTQFAVPYFIYDIYAMFLCHWHKHQVKGHGGEDGTPRALGSTWAVVRGYLHKEFLMVLHHAAMVLVCFPLSVVWRQGKGDFFLGCMLMAEVSTPFVCLGKILIQYKQQHTLLHKVNGALMLLSFLCCRVLLFPYLYWAYGRHAGLPLLSVPMAIPAHVNLGAALLLAPQLYWFFLICRGACRLFRPRGSPPPSPCQTQD
What is the function of this protein?
Involved in ceramide synthesis.  In vitro, isoform 3 stimulates the production of C16-, C18- and C20-ceramides, isoform 1 slightly increases the levels of C18- and C20-ceramides, while isoform 2 exhibits only minimal activity.  May interfere with adipogenesis by stimulating ceramide synthesis.
What are the official names of this protein?
Ceramide synthase, Protein FAM57B, TLC domain-containing protein 3B.
What are the subcellular locations of this protein?
[Isoform 1]: Golgi apparatus membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Endoplasmic reticulum membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [Isoform 3]: Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: HSCA_ECOBW
Sequence: MALLQISEPGLSAAPHQRRLAAGIDLGTTNSLVATVRSGQAETLADHEGRHLLPSVVHYQQQGHSVGYDARTNAALDTANTISSVKRLMGRSLADIQQRYPHLPYQFQASENGLPMIETAAGLLNPVRVSADILKALAARATEALAGELDGVVITVPAYFDDAQRQGTKDAARLAGLHVLRLLNEPTAAAIAYGLDSGQEGVIAVYDLGGGTFDISILRLSRGVFEVLATGGDSALGGDDFDHLLADYIREQAGIPDRSDNRVQRELLDAAIAAKIALSDADSVTVNVAGWQGEISREQFNELIAPLVKRTLLACRRALKDAGVEADEVLEVVMVGGSTRVPLVRERVGEFFGRPPLTSIDPDKVVAIGAAIQADILVGNKPDSEMLLLDVIPLSLGLETMGGLVEKVIPRNTTIPVARAQDFTTFKDGQTAMSIHVMQGERELVQDCRSLARFALRGIPALPAGGAHIRVTFQVDADGLLSVTAMEKSTGVEASIQVKPSYGLTDSEIASMIKDSMSYAEQDVKARMLAEQKVEAARVLESLHGALAADAALLSAAERQVIDDAAAHLSEVAQGDDVDAIEQAIKNVDKQTQDFAARRMDQSVRRALKGHSVDEV
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.  Involved in the maturation of IscU.
What are the official names of this protein?
Chaperone protein HscA, Hsc66.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: GLGB_YARLI
Sequence: MTLQVCKDDPWLKPFEEELLRRQALVGQWKDHFAKEGGLAEFAASYKRYGLHVNKDNSVTYREWAPGASEAVLTGDFNGWDRQQYHMTRDEYGLWSVTVPPTSDGQVAIPHNSKVKLALKTSNGQWVDRLPAWSTYVVQDLSKSPIYEAVFWNPPESEKYQWKNKSPPTPANAQIYEAHVGISSSEPRVGTYKEFTKNILPRIHKLGYNVIQLMAIMEHAYYASFGYQVTSFYAISSRYGTPEDLKELIDTAHGMGITVLLDVVHSHACKNVDDGLNNFDGTDHQYFHGGAKGDHPQWDSKLFDYGKYEVLRFLLSNLRFYIEEYHFDGFRFDGVTSMLYKHHGLGTGFSGGYHEYFGDEHVDQQAVVYLMLAHELMRELQPLLRPGEDAGNFLSIAEDVSGMPALCRPVSEGGVGFDYRLAMAIPDMWIKLVKETRDEDWDMGNIVFTLTNRRHREKTIAYAESHDQALVGDKTLAFWLMDKEMYTSMSVLSDPNPIIDRGIALHKMIRLITHSLGGEGYLNFEGNEFGHPEWLDFPREGNGSSFHYCRRQWPVVDDKLLRYQHLNEFDAAMQHRGDHYGWLSADQAYVSLKNEDDKVVVYERAGLVFVFNFHPNKSFTDYRIGVDQPGTYTLVLDSDSPEFGGFGRIDHEKTRCHTEPLEWNGRANCMHIYIPSRVALVFAREDDPRRK
What are the official names of this protein?
1,4-alpha-glucan-branching enzyme, Glycogen-branching enzyme.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: CYB_EURSP
Sequence: MTNTRKNHPLIKIINHSFIDLPAPSNISAWWNFGSLLGVCLALQIITGLFLAMHYTADTTTAFSSVTHICRDVNYGWLIRYAHANGASMFFIFLYFHIGRGIYYGSYTFMETWNIGVILLFMVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGPTLVEWIWGGFSVDKATLTRFFAFHFILPFIITAMVMIHLLFLHESGSNNPSGLNSDSDKIPFHPYYTIKDILGLLLMILTLLMLILFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILMLFPALHTAKQRSMTFRPMSQCLLWILVANLIILTWIGGQPVEYPFITIGQLASISYFCIILILMPMTSLMENHLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MB12A_BOVIN
Sequence: MDPGPGANGMPLAGLAWSSASAPPPRGFSAISCTVEGTPASFGKTFAQKSGYFLCLNPLGSLENPQENVVVDIQILVDKSPLPPGFSPVCDPLDSKASVSKKKRMCVKLVPLGAADTAVFDIRLSGKTKTVPGYLRVGDMGGFAIWCRKAKAPRPVPKPRALSRDVRDLSLDSPGQPSKGGFPERTLSRLGSRASTLRRNDSIYEASNLYGISAMDGVPFTLHPRFEGKSCGPLAFSAFADLTIKSLADIEAEYNYGFVVEKTAAARLPPSVS
What is the function of this protein?
Component of the ESCRT-I complex, a regulator of vesicular trafficking process.  Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies.  May be involved in the ligand-mediated internalization and down-regulation of EGF receptor (By similarity).
What are the official names of this protein?
Multivesicular body subunit 12A, ESCRT-I complex subunit MVB12A, Protein FAM125A.
What is the protein family that this protein belongs to?
Belongs to the MVB12 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Nucleus. Endosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Late endosome membrane; Peripheral membrane protein. Note=Colocalizes with F- actin. Some fraction may be nuclear (By similarity).
Protein: INSE4_ECOLI
Sequence: MTKTVSTSKKPRKQHSPEFRSEALKLAERIGVTAAARELSLYESQLYNWRSKQQNQQTSSERELEMSTEIARLKRQLAERDEELAILQKAATYFAKRLK
What is the function of this protein?
Involved in the transposition of the insertion sequence IS3.
What are the official names of this protein?
Transposase InsE for insertion sequence IS3D.
What is the protein family that this protein belongs to?
Belongs to the transposase 8 family.
Protein: RR4_MELAL
Sequence: MSRYRGPRLKKIRRLGALLGLTRKTPKSGSNPKKKFHSGKKEQYRIRLQEKQKLRFHYGLTERQLLRYVYIAGKAKRSTGQVLLQLLEMRLDNILFRLGMASTIPGARQLVNHRHILVNGRIVNIPSFRCKPRDIITTKDNQRSKGLVQNSIASSDPGKLPKHLTIDTLEYKGLVNKILDRKWVGLKINELLVVEY
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MRAY_COXBN
Sequence: MLLWLTNFLSQHFHAFRVFNYLTFRSIVSALTALILVLSLSPRLIKYLVSLQVGQMVRNDGPQTHLKKSGTPTMGGVLIIVAIVISVLLWGDLSNRFIWVILLVTVAFSAIGWMDDYRKIIRKNSKGLSARSKYLLQSIIGALAAVYLYFSATTGAETALVIPFLKNVLPNLGLFYIVLAYFVIVGSSNAVNLTDGLDGLALMPTVMIGAALGVFAYTTGNHFFAQYLAIPYIPGAGEVVVFCSALVGAGLGFLWYNTYPAQVFMGDVGSLGLGAALGVTAVVVRQELVYFLMGGIFVAETLSVILQVGYFKLSGGKRIFRMAPLHHHFELKGWPEPKVIVRFWIITFILVLCGLATLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PARB_TRYBB
Sequence: MAPRSLYLLAVLLFSANLFAGVGFAAAAEGPEDKGLTKGGKGKGGKGTKVSDDDTNGTDPDPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPGAATLKSVALPFAIAAVGLVAAF
What is the function of this protein?
Major surface antigen of procyclic forms.
What are the official names of this protein?
Procyclic form-specific polypeptide A-beta, PARP A-beta, Procyclin.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: C524A_DICDI
Sequence: MKTPTKYFIIFILLAALAVFVSEATSKVGQQTTTTTQQVKCSGLQCTLNKLIVAVGKFTIKQILVGIVIVLATIALHQQYVITQKKGSLPGPSFVPPFFGMLFQLIFTPFSFYEKQEKYGPISWTSIMNKFVLFVTDAEINRQVFKEENAKLYLSLGAKKILTEKAIPFIEGAPHRQLRKQLLPLFTIRALSSYLPIQESIVDEHIAMWIKNGKADINARNNCRDLNMAISTGVFVGNNTPESVRDDIAKNFFVMNEGFLCLPIDLPGTTLRKAINARVRLVEIFTDIIAKSRKRMGDGEKPQSLIDLWVEHFLNCPEEERDELSNDTIIFTLLSFMFASQDALTSSLVWTVQLMAEHPDILAKVRAEQASLRPNNEKLDLDTMRQATYTRMVVSEILRFRPPAVMVPHENIEDIVIGDNVHVPKGTMILPSIWSAHFQEGGYSDPYKFDPQRFDSVRKEDVTCAKNSLVFGAGPHFCIGKELAKNQIEVFLTKLAMSTEWTHNKTPGGDEIIFGPTIFPKDGCNITIKARN
What are the official names of this protein?
Probable cytochrome P450 524A1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RK20_CHLAT
Sequence: MTRVKRGYVARKRRKRVLQLTQGFRGAHSVLFRTANQQNIKALRYASRDRARRKRDFRRLWITRINAGARKQGLSYSQLMHRFKKCGILINRKVLAQLALLDTKTFNQLVFYTDL
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: EFPA_MYCTO
Sequence: MTALNDTERAVRNWTAGRPHRPAPMRPPRSEETASERPSRYYPTWLPSRSFIAAVIAIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFPKGPARNAATAVFAAMTAIGSVMGLVVGGALTEVSWRWAFLVNVPIGLVMIYLARTALRETNKERMKLDATGAILATLACTAAVFAFSIGPEKGWMSGITIGSGLVALAAAVAFVIVERTAENPVVPFHLFRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVMPIVVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDVQLAALDHAYTYGLLWVAGAAIIVGGMALFIGYTPQQVAHAQEVKEAIDAGEL
What are the official names of this protein?
Uncharacterized MFS-type transporter EfpA, Efflux protein A.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TF3C6_HUMAN
Sequence: MAAAADERSPEDGEDEEEEEQLVLVELSGIIDSDFLSKCENKCKVLGIDTERPILQVDSCVFAGEYEDTLGTCVIFEENVEHADTEGNNKTVLKYKCHTMKKLSMTRTLLTEKKEGEENIGGVEWLQIKDNDFSYRPNMICNFLHENEDEEVVASAPDKSLELEEEEIQMNDSSNLSCEQEKPMHLEIEDSGPLIDIPSETEGSVFMETQMLP
What is the function of this protein?
Involved in RNA polymerase III-mediated transcription.  Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters.
What are the official names of this protein?
General transcription factor 3C polypeptide 6, Transcription factor IIIC 35 kDa subunit, TFIIIC 35 kDa subunit, TFIIIC35, Transcription factor IIIC subunit 6.
What is the protein family that this protein belongs to?
Belongs to the TFIIIC subunit 6 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL36_PSE14
Sequence: MKVRASVKKLCRNCKIIRREGVVRVICSAEPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: LSPA_HELPY
Sequence: MLKTTKKSLLVFMGVFFLIFGVDQAIKYAILEGFRYESLMIDIVLVFNKGVAFSLLSFLEGGLKYLQILLILGLFIFLMRQRELFKNHAIEFGMVFGAGVSNVLDRFVHGGVVDYVYYHYGFDFAIFNFADVMIDVGVGVLLLKQFFFKQKQNKIKA
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MUTS_THESQ
Sequence: MKVTPLMEQYLRIKEQYKDSILLFRLGDFYEAFFEDAKIVSKVLNIVLTRRQDAPMAGIPYHALNTYLKKLVEAGYKVAICDQMEEPSKSKKLIRREVTRVVTPGSIVEDEFLSETNNYMAVVSEEKGRYCTVFCDVSTGEVLVHESSDEQETLDLLKNYSISQIVCSEHLKSSLRERFPGVYTESISEWYFSDLEEVEKAYNLKDIHHFELSPLALKTLAALIKYVKYTMITEDLNLKPPLLISQRDYMILDSATVENLSLIPGDRGKNLFDVLNNTETPMGARLLKKWILHPLVDRKQIEERLEAVERLVNDRVSLEEMRNFLSNVRDVERIVSRVEYNRSVPRDLVALRETLEIIPKLNEILSNFGVFNKLAFPEELVDLLRRAIEDDPLGSPGEGKVIKRGFSPELDEYRDLLEHAEERLKEFEEKERERTGIQKLRVGYNQVFGYYIEVTKANLDKIPDDYERKQTLVNSERFITPELKEFETKIMAAKERIEEMEKELFKSVCEEVKKHKEVLLKLSEDLAKMDVLSTLAYDAILYNYTKPVFSEDRLEIKGGRHPVVERFTQNFVENDIYMDNEKRFVVITGPNMSGKSTFIRQVGLISLMAQIGSFVPAQKAILPVFDRIFTRMGARDDLAGGRSTFLVEMNEMALILLKSTEKSLVLLDEVGRGTSTQDGVSIAWAISEELIKRGCKVLFATHFTELTELEKHFPQVQNKTILVKEEGKNVIFTHKVVDGVADRSYGIEVAKIAGIPDRVINRAYEILERNFKNHTKKNGKSNRFSQQIPLFPV
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: FADB_PSEFR
Sequence: MIYEGKAITVTALESGIVELKFDLKGESVNKFNRLTLNELRQAVDAIKADASVKGVIVSSGKDVFIVGADITEFVENFKLPDAELIAGNLEANKIFSDFEDLNVPTVAAINGIALGGGLEMCLAADFRVMADSAKIGLPEVKLGIYPGFGGTVRLPRLIGVDNAVEWIASGKENRAEDALKVSAVDAVVTADKLGAAALDLIKRAISGELDYKAKRQPKLEKLKLNAIEQMMAFETAKGFVAGQAGPNYPAPVEAIKTIQKAANFGRDKALEVEAAGFAKLAKTSASNCLIGLFLNDQELKKKAKVYDKIAKDVKQAAVLGAGIMGGGIAYQSASKGTPILMKDINEHGIEQGLAEAAKLLVGRVDKGRMTPAKMAEVLNGIRPTLSYGDFGNVDLVVEAVVENPKVKQAVLAEVENHVREDAILASNTSTISISLLAKALKRPENFVGMHFFNPVHMMPLVEVIRGEKSSDLAVATTVAYAKKMGKNPIVVNDCPGFLVNRVLFPYFGGFAKLVSAGVDFVRIDKVMEKFGWPMGPAYLMDVVGIDTGHHGRDVMAEGFPDRMKDDRRSAIDALYEAKRLGQKNGKGFYAYEADKKGKQKKLVDSSVLEVLKPIVYEQRDVTDEDIINWMMIPLCLETVRCLEDGIVETAAEADMGLVYGIGFPLFRGGALRYIDSIGVAEFVALADQYAELGALYHPTAKLREMAKNGQSFFG
What is the function of this protein?
Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle.  Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA.  It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
Protein: UACA_HUMAN
Sequence: MKSLKSRLRRQDVPGPASSGAAAASAHAADWNKYDDRLMKAAERGDVEKVTSILAKKGVNPGKLDVEGRSVFHVVTSKGNLECLNAILIHGVDITTSDTAGRNALHLAAKYGHALCLQKLLQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMSRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLIKNGADISLLDALGHDSSYYARIGDNLDILTLLKTASENTNKGRELWKKGPSLQQRNLTHMQDEVNVKSHQREHQNIQDLEIENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADDLESEREKLKSLLAAKEKQHEESLRTIEALKNRFKYFESDHLGSGSHFSNRKEDMLLKQGQMYMADSQCTSPGIPAHMQSRSMLRPLELSLPSQTSYSENEILKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEAASGNHRLTEELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMCEMEREKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKSLSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTLQKEIEKVYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQKYTEKKLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKCGEDQEKIHALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDSNAEILANYRKGQEEIVTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYTEVKNVKEKLVEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQTVTKLHQLLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKMEEVSKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEEVLHAKKKEISAKDEKELLHFSIEQEIKDQKERCDKSLTTITELQRRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQLTYTSGNPTKRQSQLIDTLQHQVKSLEQQLADADRQHQEVIAIYRTHLLSAAQGHMDEDVQEALLQIIQMRQGLVC
What is the function of this protein?
Modulates isoactin dynamics to regulate the morphological alterations required for cell growth and motility.  Interaction with ARF6 may modulate cell shape and motility after injury.  May be involved in multiple neurite formation (By similarity).
What are the official names of this protein?
Uveal autoantigen with coiled-coil domains and ankyrin repeats.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton. Note=Expressed diffusely in cytoplasm.
Protein: SYP_DINSH
Sequence: MRLSRYFLPVLKETPAEAQIVSHRLMLRAGMIKQASAGIYSWLPLGYKVLRRIEEIVHEEQQRAGHIPMLMPTLQSADLWRESGRYDDYGQEMLRITDRHGRDMLYGPTNEELITDIFRSNVGSYKDLPLTLYHIQWKFRDEVRPRFGVMRGREFLMKDGYNFDLTKEAALHAYNRHLVSYLRSYERMGLQAIPMRADGGPIGGDYTHEFLVLAETGESEVFYDAEITDLSFGDRQIDYDDVGQCQAVLEEFTSRYARTDETHDPDAFAKVPEARRRSARGIEVGQIFYFGTKYSDAMGATVIDKDQNQVPVHMGSHGIGVSRLLGAIIEASHDDKGIIWPEGVTPFHCGIVNLKQGDAAADAACEGLYDALTKAGLEPLYDDRNERAGGKFATMDLIGLPWRITVGPRGLKAGVVELTSRKTGESEELSPEAAVAKVVARYAGA
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_DESAL
Sequence: MERTAIYAGSFDPVTNGHLDILKRGLKLFDRIIVAILINPNKQYLFSVEERISMLEEVTKEIPNTEIDTFSGLLVDYAEQKQAHAILRGMRAVSDFEYEFQLALMNRRLNREVQTVFLMTGLRWIFTSSSIIKEAARFGGNIHGMVPELVERRIDKKMKDTGLYIPPKNNKKQKG
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPE_BART1
Sequence: MLVLTDPLQLLQALIRCPSVTPHEAGALSALEQFLKKMGFHVERPIFTDKNTDNVENLYAKMGNEGPHLMFAGHTDVVPPGALEDWTYPPFEAVIDQGKLYGRGAVDMKGGIACFIAALARVLEKRSIKGRVSLLITGDEEGTAINGTVKLLKWAEKKGEKWTAALVGEPTSVKTVGDIIKIGRRGSISGIITVKGRQGHVAFPERAANPLPLASKLIQALTQIALDQGTENFQPSNLELTTIDTGNLAVNVIPAQTTVRFNIRYNDLWTKETLMEEIEKRLSLVQEKNNSGQYPFYQLEWIPSLGDVFLTKNDKLIQVLSNAIKSVTGSLPECSTSGGTSDARFIKDYCPVVEFGLPGQTMHMVDECVALDAVETLTAIYERFIIDFFV
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.