PharMolix/UniProtQA huggingface dataset:
Protein: PUS10_MOUSE
Sequence: MLPLTEENKHVAQLLFSSGTCPRCILRFCGVDLPAPYKHPSKELLNELQKFLEPEKPELILEAPNPPLKKIRLHEDGIDNLSEDGKEGVSVTEDESMAEKPSKLRVCNVCLGILQEFCEKGFITKVCQKVEASGFEFTSVVLSVSFPPQLSVREHAAWLLVKQEMGKQSLSLGRNDVVQLKEAYKWITHPLFSEELGVPTDGKSLFEVSVVFAHPETAEDCHFLGEVCRDCFKPAKNKQSVFTRMAVLKALSKIKEEDFLGQFPCPPNSPKTVCTVLEVECTHGAVFVAGRYNKYSRNLPQTPWIIDGERKMESSVEELISDHLLAVFRAESFNFSSSGREDVDVRTLGNGRPFAVELLNPHRVHFTSQEMKELQQTINKSSDKIQVRDLQLVTREAIGHMKEGEEEKTKTYSALIWTNRAIQKKDIGFLDDLKDLKIDQKTPLRVLHRRPLAVRTRAIHSMKTHYLDEHHFRLHLKTQAGTYIKEFVHGDFGRTKPNLGSLMNVTADILELDVESVDVDWPPALDD
What is the function of this protein?
Protein with different functions depending on its subcellular location: involved in miRNA processing in the nucleus and acts as a tRNA pseudouridylate synthase in the cytoplasm.  In the cytoplasm, acts as a pseudouridylate synthase by catalyzing synthesis of pseudouridine(54) and pseudouridine(55) from uracil-54 and uracil-55, respectively, in the psi GC loop of a subset of tRNAs.  tRNA pseudouridylate synthase activity is enhanced by the presence of 1-methyladenosine at position 53-61 of tRNAs.  Does not show tRNA pseudouridylate synthase activity in the nucleus.  In the nucleus, promotes primary microRNAs (pri-miRNAs) processing independently of its RNA pseudouridylate synthase activity.  Binds pri-miRNAs.  Modulator of TRAIL/TNFSF10-induced cell death via activation of procaspase-8 and BID cleavage.  Required for the progression of the apoptotic signal through intrinsic mitochondrial cell death.
What are the official names of this protein?
tRNA pseudouridine synthase Pus10, Coiled-coil domain-containing protein 139, tRNA pseudouridine 55 synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase Pus10 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Mitochondrion. Note=Localizes mainly in the nucleus. tRNA pseudouridylate synthase activity is restricted to the cytoplasm. Translocates from nucleus to mitochondria during TRAIL-induced apoptosis.
Protein: MSCL_RHILW
Sequence: MLNEFKAFIARGNVMDLAVGVIIGGAFGGIVKSLVDDLIMPIVGAIFGGFDFSNYFLPLSSAVNAPTLAAARAQGAVFAYGSFLTVLINFLILAWIIFLMVKGVNYLRLQVERQEKAAPEELPPPPADVQLLTEIRDLLATRPTA
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FIS1_EMENI
Sequence: MTSSNLPYAADAESPLKPAELQVLRAQYEKEGDYVGVQTKFNYAWGLIKSNFRADQQEGVRLLSEIFRAHPERRRECLFYLALGNYKLGNYGEARRYNDLLIDKEPGNLQAASLRTLIDDRVSREGMVGIAIVGGLALAAGVVGGLLFRGQRR
What is the function of this protein?
Has a role in mitochondrial fission.  Has a role in outer membrane fission but not matrix separation (By similarity).
What are the official names of this protein?
Mitochondrial fission 1 protein.
What is the protein family that this protein belongs to?
Belongs to the FIS1 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: HRCA_MALP2
Sequence: MKEITQRQKELLKYIVEDYVATANPVGSKVVIEKYMPNISAATVRNDMAFLEKLGLLEKNHTSSGRVPSTAGYKFYEKNFSKPYINDENLKLKLRNVFADRTMSIDVVIEESCKIISESTKLPMIKIENNTEVLLKRIDMVEINKQSAMVIVITSDGNLTKNIIHFKDDSILKDISICIRIFNDRLIDCPIKEIATKIDSMKSIIKEKVKEYEFVLQELIERIFQIKSKMIKTVHGQSSLLAVPEFQDTEKLKEILQILESTSIWEQIAFKQNQTGSNTLITFGDEVSHEDIVFAQTDLNINEQNKTKLVMVAPTRVDYSKIKGLLEFIKNEFEKGWK
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: NADK_VIBA3
Sequence: MKKPFEVIAIIGKPRDQQAIQTHRELYQWLSTEGYQVFVDDRLATILDDIPQEHFSSLIELGKRADLAIVVGGDGNMLGAARILSRFDISVIGVNRGNLGFLTDLNPENFQSALTDVLKGEFMEEERFLLETEIHRHGQIKSHNAALNEAVLHPGQVAHMIEFEVYIDDSFAFSQRSDGLIVSTPTGSTAYSLSGGGPILSSSLNAISLVPMFPHTLSSRPLVVDGKRRIKLIVSPDNRGTQEVSCDGQISLPVSPGDEIHIYQSPNVLKLIHPKDYNYYHVLRNKLGWSSKLF
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YL899_MIMIV
Sequence: MNSKISVSNLDSNVIDIITRILKSQSNTDVDNATDIIIGAISKNILTLQDDRDLSSIKQIFQSINDSECAFIGRQIDNEIVFTVQDIAMYLARDTFNPLNNDVNTFIKYSWSSYSNKQGTNEKRDTINIVIKNQNVETYTYTKIDLPYLLVHVARYLSIFN
What are the official names of this protein?
Uncharacterized protein L899.
What is the protein family that this protein belongs to?
Belongs to the mimivirus L761/L899 family.
What are the subcellular locations of this protein?
Virion.
Protein: SRAP_STAAC
Sequence: MSKRQKAFHDSLANEKTRVRLYKSGKNWVKSGIKEIEMFKIMGLPFISHSLVSQDNQSISKKMTGYGLKTTAVIGGAFTVNMLHDQQAFAASDAPLTSELNTQSETVGNQNSTTIEASTSTADSTSVTKNSSSVQTSNSDTVSSEKSEKVTSTTNSTSNQQEKLTSTSESTSSKNTTSSSDTKSVASTSSTEQPINTSTNQSTASNNTSQSTTPSSVNLNKTSTTSTSTAPVKLRTFSRLAMSTFASAATTTAVTANTITVNKDNLKQYMTTSGNATYDQSTGIVTLTQDAYSQKGAITLGTRIDSNKSFHFSGKVNLGNKYEGHGNGGDGIGFAFSPGVLGETGLNGAAVGIGGLSNAFGFKLDTYHNTSKPNSAAKANADPSNVAGGGAFGAFVTTDSYGVATTYTSSSTADNAAKLNVQPTNNTFQDFDINYNGDTKVMTVKYAGQTWTRNISDWIAKSGTTNFSLSMTASTGGATNLQQVQFGTFEYTESAVTQVRYVDVTTGKDIIPPKTYSGNVDQVVTIDNQQSALTAKGYNYTSVDSSYASTYNDTNKTVKMTNAGQSVTYYFTDVKAPTVTVGNQTIEVGKTMNPIVLTTTDNGTGTVTNTVTGLPSGLSYDSATNSIIGTPTKIGQSTVTVVSTDQANNKSTTTFTINVVDTTAPTVTPIGDQSSEVYSPISPIKIATQDNSGNAVTNTVTGLPSGLTFDSTNNTISGTPTNIGTSTISIVSTDASGNKTTTTFKYEVTRNSMSDSVSTSGSTQQSQSVSTSKADSQSASTSTSGSIVVSTSASTSKSTSVSLSDSVSASKSLSTSESNSVSSSTSTSLVNSQSVSSSMSDSASKSTSLSDSISNSSSTEKSESLSTSTSDSLRTSTSLSDSLSMSTSGSLSKSQSLSTSISGSSSTSASLSDSTSNAISTSTSLSESASTSDSISISNSIANSQSASTSKSDSQSTSISLSTSDSKSMSTSESLSDSTSTSGSVSGSLSIAASQSVSTSTSDSMSTSEIVSDSISTSGSLSASDSKSMSVSSSMSTSQSGSTSESLSDSQSTSDSDSKSLSQSTSQSGSTSTSTSTSASVRTSESQSTSGSMSASQSDSMSISTSFSDSTSDSKSASTASSESISQSASTSTSGSVSTSTSLSTSNSERTSTSMSDSTSLSTSESDSISESTSTSDSISEAISASESTFISLSESNSTSDSESQSASAFLSESLSESTSESTSESVSSSTSESTSLSDSTSESGSTSTSLSNSTSGSTSISTSTSISESTSTFKSESVSTSLSMSTSTSLSDSTSLSTSLSDSTSDSKSDSLSTSMSTSDSISTSKSDSISTSTSLSGSTSESKSDSTSMSISMSQSTSGSTSTSTSTSLSDSTSTSLSLSASMNQSGVDSNSASQSASNSTSTSTSESDSQSTSSYTSQSTSQSESTSTSTSLSDSTSISKSTSQSGSVSTSASLSGSESESDSQSISTSASESTSESASTSLSDSTSTSNSGSASTSTSLSNSASASESDLSSTSLSDSTSASMQSSESDSQSTSASLSDSLSTSTSNRMSTIASLSTSVSTSESGSTSESTSESDSTSTSLSDSQSTSRSTSASGSASTSTSTSDSRSTSASTSTSMRTSTSDSQSMSLSTSTSTSMSDSTSLSDSVSDSTSDSTSASTSGSMSVSISLSDSTSTSTSASEVMSASISDSQSMSESVNDSESVSESNSESDSKSMSGSTSVSDSGSLSVSTSLRKSESVSESSSLSCSQSMSDSVSTSDSSSLSVSTSLRSSESVSESDSLSDSKSTSGSTSTSTSGSLSTSTSLSGSESVSESTSLSDSISMSDSTSTSDSDSLSGSISLSGSTSLSTSDSLSDSKSLSSSQSMSGSESTSTSVSDSQSSSTSNSQFDSMSISASESDSMSTSDSSSISGSNSTSTSLSTSDSMSGSVSVSTSTSLSDSISGSTSVSDSSSTSTSTSLSDSMSQSQSTSTSASGSLSTSISTSMSMSASTSSSQSTSVSTSLSTSDSISDSTSISISGSQSTVESESTSDSTSISDSESLSTSDSDSTSTSTSDSTSGSTSTSISESLSTSGSGSTSVSDSTSMSESNSSSVSMSQDKSDSTSISDSESVSTSTSTSLSTSDSTSTSESLSTSMSGSQSISDSTSTSMSGSTSTSESNSMHPSDSMSMHHTHSTSTSRLSSEATTSTSESQSTLSATSEVTKHNGTPAQSEKRLPDTGDSIKQNGLLGGVMTLLVGLGLMKRKKKKDENDQDDSQA
What is the function of this protein?
Mediates binding to human platelets, possibly through a receptor-ligand interaction.  Probably associated with virulence in endovascular infection (By similarity).
What are the official names of this protein?
Serine-rich adhesin for platelets, Adhesin SraP, Staphylococcus aureus surface protein A.
What is the protein family that this protein belongs to?
Belongs to the serine-rich repeat protein (SRRP) family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor. Note=Exported by the accessory SecA2/SecY2 system. Anchored to the cell wall by sortase A (By similarity).
Protein: YCDX_ECOLC
Sequence: MYPVDLHMHTVASTHAYSTLSDYIAQAKQKGIKLFAITDHGPDMEDAPHHWHFINMRIWPRVVDGVGILRGIEANIKNVDGEIDCSGKMFDSLDLIIAGFHEPVFAPHDKATNTQAMIATIASGNVHIISHPGNPKYEIDVKAVAEAAAKHQVALEINNSSFLHSRKGSEDNCRAVAAAVRDAGGWVALGSDSHTAFTMGEFEECLKILDAVDFPPERILNVSPRRLLNFLESRGMAPIAEFADL
What are the official names of this protein?
Probable phosphatase YcdX.
What is the protein family that this protein belongs to?
Belongs to the PHP family.
Protein: SELO_BURCJ
Sequence: MSFSRSAADAADTLPDLAATLGTPAEGAFVTLGDAFHTRLPAAPLAAPYVVGFSDEVAQLLDLPPTLAAQPGFAELFTGNPTRDWPANAMPYASVYSGHQFGVWAGQLGDGRALTIGELPGTDGRRYELQLKGGGRTPYSRMGDGRAVLRSSIREFLCSEAMHHLGIPTTRALTVIGSDQPVVREEIETAAVVTRVSESFVRFGHFEHFFSNDRPDLLRQLADHVIDRFHPACRDADDPYLALLEAATLRTADLVAQWQAVGFCHGVMNTDNMSILGVTIDYGPFGFVDAFDANHICNHSDTGGRYAYRMQPRIAHWNCYCLAQALLPLIGLQHGIADDDARAERAVDDAQAVLAKFPERFGPALERAMRAKLGLALEREGDAELANKLLETMHASHADFTLTFRRLAQISKHDASRDAPVRDLFIDREAFDAWANLYRARLSEETRDDAARAVAMNRANPKYVLRNHLAEVAIRRAKEKDFSEVERLAQILRRPFDEQPEHEAYAALPPDWAGSLEVSCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: RSMI_MICOL
Sequence: MASIQLARTTRGGDGVARADGTRQADEAGSGTLYLVPTPIGNPGDITLRAIEVLRRVGVVASEDTRHTYRLFQSLEIDARLVSYHDHNEESRSRQLLGLLREGTDVALVSDAGTPLVNDPGYRLVAAAVEADVPVRPLPGATASVTALIGSGMPNHQFHYVGFLPRKEAARRAALTALRSTPATLIFFEAPHRIVAMLADLAAVLGDRPAALARNLTKDDEEFLRGRLNELTARLRVEQVVRGQFTVVVAGSPEAHADEDRALAARLTETLVRHGAEARLIREVVREVTGLPRNWVYEQVRLATERSGPLGNS
What is the function of this protein?
Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase I, 16S rRNA 2'-O-ribose C1402 methyltransferase, rRNA (cytidine-2'-O-)-methyltransferase RsmI.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_CHLPD
Sequence: MIQKETNLVVADNSGAKKVRCIHVFGGTGRRYAALGDQIIVSIKAAVPGGVVKKKDVCKAVVVRCVKEQRRKDGSYIRFDENAVVLLNAQGEPRGTRIFGPVARELRDRKYMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: NDHJ_PELHO
Sequence: MQGPLSAWLVKRRLVHRSLGFDYQGIETLEIKSEDWHSVAVILYVYGYNYLRSQCAYDVAPGGLLASVYHFTRIEYGIDQPEEVCIKVFLARSNPRIPSIFWVWKSADFQERESYDMLGISYDNHPRLKRILMPESWIGWPLRKDYIAPNFYEIQDAH
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit J, chloroplastic, NAD(P)H dehydrogenase subunit J, NADH-plastoquinone oxidoreductase subunit J.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: ARGR_STAAR
Sequence: MPKKSVRHIKIREIISNEQIETQDELVKRLNDYDLNVTQATVSRDIKELQLIKVPIPSGQYVYSLPNDRKFHPLEKLGRYLMDSFVNIDGTDNLLVLKTLPGNAQSIGAILDQINWEEVLGTICGDDTCLIICRSKEASDEIKSRIFNLL
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IMPCT_CAEEL
Sequence: MSDEEQRIAEIESLASIFPDLLEETTDKQLVFKFDRDIGMTINLPEDYPSISPPIFELSGPYLRREQKEVLHNSLNDVYIENIGFPVIFNWISLVQDFIRDLPEEVAEPSHVADDVVTPMAEEIDDMNIRHGEVLTDRKSAFQAHLAEVRSKEDVDRVMRILKSNTKICRATHNITAYRYMTEINGKPIHHHDCVDDGEFGASSKMLELMDRMKADNVMVVVSRWYGGIHLGPDRFRHINNLTRQILSDNNYGPKKS
What is the function of this protein?
Translational regulator that ensures constant high levels of translation under amino acid starvation.  Plays a role as a negative regulator of the gcn-2 kinase activity; impairs gcn-1-mediated gcn-2 activation, and hence gcn-2-mediated eIF-2-alpha phosphorylation and subsequent down-regulation of protein synthesis in amino acid-starved cells.  Plays a role in differentiation of neuronal cells by stimulating neurite outgrowth.
What are the official names of this protein?
Protein IMPACT homolog.
What is the protein family that this protein belongs to?
Belongs to the IMPACT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPH_ACIF2
Sequence: MDILLANPRGFCAGVNRAIQIVDRALELFGAPIYVRHEVVHNRHVVEDLRARGAIFVEELDEVPDAATVIFSAHGVPIAVREHAAARGLSVFDATCPLVTKVHMEVKKYSRDGMEMVLIGHAGHPEVEGTMGQVEEGMMYLVSNVSDVATLAPRNPDKLAYITQTTLSMDDTAEVIVALRSRFPLIEGPKKDDICYATQNRQDAVKSLAPDVDILLVVGAPNSSNSSRLAELGTRLGTQTHLIEDAQQLRREWFEGVGKIGISAGASAPESLVQEIMDTLRGWGARVPQEMPGVEEKVTFSLPLALIQAQTRREGA
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: LIPA_ECOLI
Sequence: MSKPIVMERGVKYRDADKMALIPVKNVATEREALLRKPEWMKIKLPADSTRIQGIKAAMRKNGLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPFCDVAHGRPVAPDANEPVKLAQTIADMALRYVVITSVDRDDLRDGGAQHFADCITAIREKSPQIKIETLVPDFRGRMDRALDILTATPPDVFNHNLENVPRIYRQVRPGADYNWSLKLLERFKEAHPEIPTKSGLMVGLGETNEEIIEVMRDLRRHGVTMLTLGQYLQPSRHHLPVQRYVSPDEFDEMKAEALAMGFTHAACGPFVRSSYHADLQAKGMEVK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.  Free octanoate is not a substrate for LipA.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSDA_MYCTE
Sequence: MREFGNPLGDRPPLDELARTDLLLDALAEREEVDFADPRDDALAALLGQWRDDLRWPPASALVSQDEAVAALRAGVAQRRRARRSLAAVGSVAAALLVLSGFGAVVADARPGDLLYGLHAMMFNRSRVSDDQIVLSAKANLAKVEQMIAQGQWAEAQDELAEVSSTVQAVTDGSRRQDLINEVNLLNTKVETRDPNATLRPGSPSNPAAPGSVGNSWTPLAPVVEPPTPPTPASAAEPSMSAGVSESPMPNSTSTVAASPSTPSSKPEPGSIDPSLEPADEATNPAGQPAPETPVSPTH
What is the function of this protein?
An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigD.  ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP).  RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses.  The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P), while cytoplasmic proteases finish degrading the regulatory protein, liberating the sigma factor (By similarity).
What are the official names of this protein?
Anti-sigma-D factor RsdA, Regulator of SigD, Sigma-D anti-sigma factor RsdA.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: CFDP1_CAMDR
Sequence: MEEFDSEDFSTSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTKGKKRKAQSIPARKRKQGLSLEEEEEDANEESGGSSSEEEDAAAEQEKGIGAEDARKKKEDELWASFLNDVGPKSKVPPSTQVKREEETEETGSSKLLVKAEELEKPKETEKVKITKVFDFAGEEVRVTKEVDATSKEAKSFFKQNEKEKPQTNVPAALPSLPAGSGLKRSSGMSNLLGKIGAKKQKMSTLEKSKLDWESFKEEEGIGEELAIHNRGKEGYIERKAFLDRVDHRQFEIERDLRLSKMKP
What is the function of this protein?
May play a role during embryogenesis.
What are the official names of this protein?
Craniofacial development protein 1, Bucentaur.
What are the subcellular locations of this protein?
Chromosome, centromere, kinetochore.
Protein: LMBL2_RAT
Sequence: MEKPRGTEETPSSEPMEEEEDDDLELFGGYDSFRSYNSSAGSESSSYLEESSEAENEDREAGELPTSPLHLFSSANNRALDGSGSEPAVCEMCGIVGTREAFFSKTKRFCSVSCSRSYSSNSKKASILARLQGKPPTKKAKVLHKAAWSAKIGAFLHAQGTGQLADGTPTGQDALVLGFDWGKFLKDHSYKAAPVGCFKHVPLYDQWEDVMKGMKVEVLNSDAVLPSRVYWIATVIQAAGYRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRTIHAKFTDWKSYLMKRLVGSRTLPADFHIKMVESMKYPFRQGMRLEVVDKTQVSRTRMAVVDTVIGGRLRLLYEDGDSDDDFWCHMWSPLIHPVGWSRRVGHGIKMSERRCDMSHHPTFRKIYCDAVPYLFKKVRAVYTEGGWFEEGMKLEAIDPLNLGNICVATICKVLLDGYLMICVDGGPSTDGSDWFCYHASSHAIFPATFCQKNDIELTPPKGYETQPFDWESYLEKTKSKAAPARLFNMDCPNHGFKVGMKLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDNEYDQWVDCESPDIYPVGWCELTGYQLQPPVSAEPNTPQKGKDATKKKKKQFGKKRKRIPSAKTRPLRQSSKKPLLEDNLEALGVSEPVPDDIIAVCVKEEHQDLPSPDRSPSPLLPLPTESIKQERDS
What is the function of this protein?
Putative Polycomb group (PcG) protein.  PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility.  Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis.  Binds to monomethylated and dimethylated 'Lys-20' on histone H4.  Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27' (By similarity).
What are the official names of this protein?
Lethal(3)malignant brain tumor-like protein 2, L(3)mbt-like protein 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACOT2_RAT
Sequence: MVASSFAVLRASRLCQWGWKSWTQLSGPPPLSTGGRTTFARTNATLSLEPGSRSCWDEPLSITVRGLAPEQPVTLRAALRDEKGALFRAHARYRADAGGELDLARAPALGGSFTGLEPMGLIWAMEPERPLWRLVKRDVQKPYVVELEVLDGHEPDGGQRLAQAVHERHFMAPGVRRVPVRDGRVRATLFLPPEPGPFPEIIDLFGVGGGLLEYRASLLAGKGFAVMALAYYNYDDLPKTMETMRIEYFEEAVNYLRGHPEVKGPGIGLLGISKGGELGLAMASFLKGITAAVVINGSVAAVGNTVCYKDETIPPVSLLRDKVKMTKDGLLDVVEALQSPLVDKKSFIPVERSDTTFLFLVGQDDHNWKSEFYAREASKRLQAHGKEKPQIICYPEAGHYIEPPYFPLCSAGMHLLVGANITFGGEPKPHSVAQLDAWQQLQTFFHKQLSGKS
What is the function of this protein?
Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels (By similarity).  Displays higher activity toward long chain acyl CoAs (C14-C20) (PubMed:7744868).  The enzyme is involved in enhancing the hepatic fatty acid oxidation in mitochondria (By similarity).
What are the official names of this protein?
Acyl-coenzyme A thioesterase 2, mitochondrial, Acyl-CoA thioesterase 2, ARTISt/p43, Acyl coenzyme A thioester hydrolase, MTE-I, Very-long-chain acyl-CoA thioesterase.
What is the protein family that this protein belongs to?
Belongs to the C/M/P thioester hydrolase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: Y6065_DICDI
Sequence: MNRFRVATDQLDLYKASLMNRAFSSNQNSRNNGKYFLQQLTQFQSTEIKGEGSVIRNLDN
What are the official names of this protein?
Putative uncharacterized protein DDB_G0280597.
Protein: ISOC2_RAT
Sequence: MAAARASLGRIFPESSILFLCDMQEKLRDRVLYFPQIVSMAARMLKVARILDVPVLLTEHYPQGLGPTVPELGAQGVRTMSKTSFSMVPPLQQELDKLPQLKSVLLCGIETQVCILNTALDLLDRGLQVHVAVDACSSQSEMNRLVALARMQHSGVFLSTSEALTLQLIKDAAHPQFKEIQKILKEPVPEIGLLGFFQGMNNPLLPNSRP
What are the official names of this protein?
Isochorismatase domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the isochorismatase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes to the nucleus in the presence of CDKN2A.
Protein: SCAM4_RAT
Sequence: MAGKENNFPPLPHFLPLKPCFYQDFSDEIPVEHQVLVKRIYRLWMFYCTTLGVNLVACLAWWIAGGAGANFGLAMLWLVLFTPCSYVCWFRPAYKAFRADSSFNFMAFFFIFGAQFVLTVIQAIGFSGWGACGWLATIGFFGTSVGAAVVMLIPAIMFSLSAVVMAITIVKVHRIYRGAGGSLQKAQTEWSAGTWRNPPSREAQFNSFSGNSLPEYPTVPSYSTSGSQWP
What is the function of this protein?
Probably involved in membrane protein trafficking.
What are the official names of this protein?
Secretory carrier-associated membrane protein 4, SCAMP-4, Secretory carrier membrane protein 4.
What is the protein family that this protein belongs to?
Belongs to the SCAMP family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GLO2_VIBC3
Sequence: MLQIKSIPAFDDNYIWLIQNRDRDCAVVDPGSAEPVLAYLKQHDLNLKAVLITHHHHDHIGGVAELVHQFPEIHVVGPAQEPIPTLTHPVEDGDQIELFDERFMVLGLPGHTLGHIGYVGDGKLFCGDVLFSAGCGRVFEGTMEQMFSSLNKLLSLPEETQVYSAHEYTAANVAFALAVEPENEQLHIYRDEVSRLRAQNQPTLPTTLGREKWVNPFLRTQEPSVIRSVASQVSTLDPLTIFTALREWKNEF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.