PharMolix/UniProtQA huggingface dataset:
Protein: CMGA_RAT
Sequence: MRSSAALALLLCAGQVFALPVNSPMTKGDTKVMKCVLEVISDSLSKPSPMPVSPECLETLQGDERVLSILRHQNLLKELQDLALQGAKERAQQQQQQQQQQQQQQQQQQQQHSSFEDELSEVFENQSPAAKHGDAASEAPSKDTVEKREDSDKGQQDAFEGTTEGPRPQAFPEPKQESSMMGNSQSPGEDTANNTQSPTSLPSQEHGIPQTTEGSERGPSAQQQARKAKQEEKEEEEEEKEEEEEEKEEKAIAREKAGPKEVPTAASSSHFYSGYKKIQKDDDGQSESQAVNGKTGASEAVPSEGKGELEHSQQEEDGEEAMAGPPQGLFPGGKGQELERKQQEEEEEEERLSREWEDKRWSRMDQLAKELTAEKRLEGEDDPDRSMKLSFRARAYGFRDPGPQLRRGWRPSSREDSVEARGDFEEKKEEEGSANRRAEDQELESLSAIEAELEKVAHQLQALRRG
What is the function of this protein?
Serpinin regulates granule biogenesis in endocrine cells by up-regulating the transcription of protease nexin 1 (SERPINE2) via a cAMP-PKA-SP1 pathway.  This leads to inhibition of granule protein degradation in the Golgi complex which in turn promotes granule formation (By similarity).  Serpinin and pGlu-serpinin can enhance both myocardial contractility (inotropy) and relaxation (lusitropy) and this cardio-stimulation requires a beta 1-adrenergic receptor/adenylate cyclase/cAMP/PKA pathway (PubMed:22459152).
What are the official names of this protein?
Chromogranin-A, CgA.
What is the protein family that this protein belongs to?
Belongs to the chromogranin/secretogranin protein family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle. Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle. Secreted. Note=Associated with the secretory granule membrane through direct interaction to SCG3 that in turn binds to cholesterol-enriched lipid rafts in intragranular conditions. In pituitary gonadotropes, located in large secretory granules. SUBCELLULAR LOCATION: [Serpinin]: Secreted. Cytoplasmic vesicle, secretory vesicle. Note=Pyroglutaminated serpinin localizes to secretory vesicle.
Protein: YEDA_ECO57
Sequence: MRFRQLLPLFGALFALYIIWGSTYFVIRIGVESWPPLMMAGVRFLAAGILLLAFLLLRGHKLPPLRPLLNAALIGLLLLAVGNGMVTVAEHQNVPSGIAAVVVATVPLFTLCFSRLFGIKTRKLEWVGIAIGLAGIIMLNSGGNLSGNPWGAILILIGSISWAFGSVYGSRITLPVGMMAGAIEMLAAGVVLMIASMIAGEKLTALPSLSGFLAVGYLALFGSIIAINAYMYLIRNVSPALATSYAYVNPVVAVLLGTGLGGETLSKIEWLALGVIVFAVVLVTLGKYLFPAKPVVAPVIQDASSE
What are the official names of this protein?
Uncharacterized inner membrane transporter YedA.
What is the protein family that this protein belongs to?
Belongs to the EamA transporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRMD_PSEPW
Sequence: MGNLRVDVITLFPEMFSAITEYGITSRAVKQGLLQVTCWNPRDYTTDRHHTVDDRPFGGGPGMVMKIKPLEDALVSARQATGASAKVIYLSPQGRKLTQQAVKGLAEQESLILIAGRYEGIDERFIEAHVDEEWSIGDYVLSGGELPAMVLIDAVTRLLPGALGHVDSAEEDSFTDGLLDCPHYTRPEVYADQRVPDVLLSGNHAHIRRWRMKQSLGRTFERRADLLESRSLSGEEKKLLEEYLRERDDS
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRP1_YEAST
Sequence: MSSDEEDFNDIYGDDKPTTTEEVKKEEEQNKAGSGTSQLDQLAALQALSSSLNKLNNPNSNNSSSNNSNQDTSSSKQDGTANDKEGSNEDTKNEKKQESATSANANANASSAGPSGLPWEQLQQTMSQFQQPSSQSPPQQQVTQTKEERSKADLSKESCKMFIGGLNWDTTEDNLREYFGKYGTVTDLKIMKDPATGRSRGFGFLSFEKPSSVDEVVKTQHILDGKVIDPKRAIPRDEQDKTGKIFVGGIGPDVRPKEFEEFFSQWGTIIDAQLMLDKDTGQSRGFGFVTYDSADAVDRVCQNKFIDFKDRKIEIKRAEPRHMQQKSSNNGGNNGGNNMNRRGGNFGNQGDFNQMYQNPMMGGYNPMMNPQAMTDYYQKMQEYYQQMQKQTGMDYTQMYQQQMQQMAMMMPGFAMPPNAMTLNQPQQDSNATQGSPAPSDSDNNKSNDVQTIGNTSNTDSGSPPLNLPNGPKGPSQYNDDHNSGYGYNRDRGDRDRNDRDRDYNHRSGGNHRRNGRGGRGGYNRRNNGYHPYNR
What is the function of this protein?
RNA-binding protein, which is involved in the polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with the cleavage factor CFIA complex and the cleavage and polyadenylation factor (CPF) complex.  May be involved in regulation of poly(A) site selection.  Is involved in nonsense-mediated mRNA decay.  Seems to bind to an RNA downstream sequence element (DSE) located 3' of a nonsense codon and may mark the transcript for decay.
What are the official names of this protein?
Nuclear polyadenylated RNA-binding protein 4, Cleavage factor IB, CFIB, Heterogeneous nuclear ribonucleoprotein 1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, Stress granule.
Protein: SLX1_DROMO
Sequence: MLILRLTLAGDREALAQKGHFYGVYLLCSQSVDVRHRGKCYVGFTVNPKRRIRQHNRGSSFGGAKKTSKKGPWQMVMIVHGFPNKIVALQFEWAWQQPTLSTRLKIFDDLRRKLPRETHFDYNFRIVNRMLGVGPWHRLPLTVRWLETDYEREFQLPLPRHMRIVSGKVAITTSQRALAVKRTAAAAAATASWSSECHLCMQRIEHPERSRFSCLNASCCLSCHMLCLASYLLDDQPGQYLPIVGNCPLCETPLVWAELLERKRFEQGVQIQGEDENEEEDRDELSDCPDVDSDVEHICELSD
What is the function of this protein?
Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination.  Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
What are the official names of this protein?
Structure-specific endonuclease subunit SLX1 homolog.
What is the protein family that this protein belongs to?
Belongs to the SLX1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL29_CLOBM
Sequence: MKARELQELRKSSPQELQSKLNDLKAELFNLRFQLATGQLENPMRIREVKKSIAQIKTILREEEIRAYQQ
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: TRPD_PELTS
Sequence: MIKNAIKKVVSGQHLSEEEAGAVMEQIMEGGASPAQIASLLTAMRLKGETVDEITGFARVMRQKSTRVKSKHPVLVDTCGTGGDGAGTFNISTAAAFVVAGAGVPVAKHGNRSVSSRCGSADVLEELGVRVDLDREAVEECLNMVGMAFLFAPLLHRSMGYVAGPRREIGIRTVFNILGPLTNPAGANAQVLGVYSPFLAEMLAKVLARLGVSRAFVVHGAGGLDEISLAGPSILCEVRNGSVRRGLLDPARFGFRYAPVSVLAGGTPRENAAIALKILEGERGARRDVVVLNAALGLVAGGKARNIAEGLEIAALSIDSGLAVAKLRELVEFTGNLSCGEAAVR
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: MNME_CLOPE
Sequence: MKEFDTIAAIATALGEGGIAIIRVSGNKALEIVNKIFRGINGKDLLDIKPYTMRYGHMIDENNEIIDEVIVSFMKGPRSFTAEDTVEINCHGGIVATNKVLQNVIKAGARLAEPGEFTKRAFLNGRIDLSQAEAVMDIITAKTELSMKSAMTQSQGRLSTEINNLRKEALDILALIEYAVDFTEDDEEPDETIPVKVKEDVITLRGKVNNLIDTADEGKLIRDGLSMVIVGKPNVGKSSLLNALLNEKRAIVTDIAGTTRDVIEEYINLDGIPVRLVDTAGIRETEDVVEKIGVEKSKEKINEADLVILMLDTSRELDEEDKEIIDYIKDRKYIVLLNKVDLDRKLSSEIVDNLENKIELSAKTGFGIDDLKSKIKDLFFNGSIDAESVMVTNTRHKEALYRASENLDGALNGLNNNEFLDLVSIYVTSALRALGEITGAELEEDLVNKIFAEFCCGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KUP3_LEGPA
Sequence: MPSTRNIEKHNDSNPTLRALSLSALGIVYGDIGTSPLYTFKTVILLAGGGTPDVTTIMGSASLIIWTLIIIASVKYICFALRIDNDGEGGILALMSLLSLKLKQKPFIIAVGLMGAALIYGDGTITPAISVLSAVEGLEILSPSLKYYVLPIAITILITLFAIQSKGTTTIGKAFGPVMAFWFLTIGILGARGVIQHPFVLAAINPVYGLNFLFSNGATGFFILCGVFLCATGAEALYADLGHFGTAPIRCTWFGLAFPSLIFNYLGQAALVLEGASTEHNIFYMLCPSDFLLPLIILSTVATIIASQAIITGAFSMTRQAMQLGWLPRLRVTQTSSEGYGQIYIGVVNWLLMLATLGLIIGFGSSEKLAAAYGIAVSATMLCTTVLLFIALHKLWKWNIITSGLVAGLFMIVDASFFAANLTKFINGGYIPITLAIIIYSMMYIWHKGYKTIAIKQKEKNITVDSFLDSIQKEGVVRVSKTAVFLTSKEQDIPPTLVWHVKKNHVLQDKVIILNINNLSIPWCKPGDQLQIVETGAGIWHAVANYGFMEQPHIPKLLKKLEAQGYDINIKDITYYIGHETIFVRNARHTLSKYIKILFVFMHRNALPMSNYFHLPPESVFEIGRQIEI
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup 3.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HTPG_FRATW
Sequence: MSEKKYTFETEVDKLLHLVIHSLYSNREIFLRELVSNSSDAIEKLRYESISNAALNEDDTDYAIRIDFDKDAKTITVSDNGIGMTEEEVIENLGTIAKSGTKKFLESLTGDKSKDNELIGQFGVGFYSSFIVADKVTVRTRKAGQDKSQATKWVSDAQNGFTVETITKEKRGTEVILHIKKEHLDLLEYHVLKGLVNKYSDCINTPIQMKKVEYDKDGKQTVKDEYETVNNTKAIWLRSKDEVTDEEYQEFYKYISHDFADALMWIHNKVEGNLEYNSLLYIPQNKPFDFWNRDKDYGLSLYVRRVFIMENKELLPPYLRFVKGVIDSADLPLNVSREILQHNKVIDKIKKAITTKILSELKKLASKDKEKYQKFWDSFGQVLKEGVSDDYSNKEKIAGLLRFATTQSGDSKQTVSLADYISRMKEGQDTIYYITSDSYKAAANNPQLEAFKKKGIEVILMTDRIDEWMMSTLTEFDGKHMKSIIKGDIDLDKFETPENKEKFEKEAKDFEKVLKEIKEVLKDKVEDVRLSKRLTDSPSCVVVNDYGMSLHMQKMMEEAGQSFMPGMGMKPILELNAEHNLVQKLKNEADTEIFADLSELLLLQAMFVEGAKIEDPMAFVKLVNKYIR
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P2C45_ORYSJ
Sequence: MGYLSSVIPTDGSPVSGGGLSQNGKFSYGYASSPGKRASMEDFYETRIDSVDGQIIGLFGVFDGHGGAKVAEYVKQNLFSHLLRHPKFISDTKVAIDDAYKSTDSEFLESDSSQNQCGSTASTAVLVGDRLFVANVGDSRAIICRGGNAIAVSKDHKPDQTDERQRIEDAGGFVMWAGTWRVGGVLAVSRAFGDKLLKQYVVVDPEIREEVIDHSLEFLILASDGLWDVVTNEEAVDMTRSIHDPEEAAKKLLQEAYKRESSDNITCVVVRFLHGQGSSGYA
What are the official names of this protein?
Probable protein phosphatase 2C 45, OsPP2C45.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: ENO_STRGC
Sequence: MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYGGLGTQKAVDNVNNVIAEAIIGYDVRDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPIAFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDGVETIIAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTAAEQIDYLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLSRGIKEGCANSILIKVNQIGTLTETFDAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDQLGEVAQYKGLQAFYNLKK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: Y3427_DROME
Sequence: MEATDQEVMLEGREDLMSTSATSSTNGGDTNGCGKKLSVTSPDPTPYVTKQRVTRPTPPAPSKNPMQFVQIKPCNLYQTAQEQLKKAEEVKKLKEVKKEEPEEWQNNLDNWKSSRRKRVEHIIDRAVETKKLELEEHDRLRRKSKTFTEMMEERAERGGPRGRAKLASLAVYNEDETNDLSDLGIGTSSASGKSSLSGDYDNNSVMSDHAAELDKAIGAASSVAAGVTAQNVDEQLNHINRNGSNGNHGNGAAVGQTGPSNSSKSAGRQYISSPGYDTSSSNAQASSPDLCEYTYEGAIQDYKQRVQRASSNGNGNANGKLIGEHIAYPTRRGSKIEDRLSGFEVTSPSDTQEGVEKQKVDVPKVDISKRKEIFEQAKAEVSNGGAPAAPKLVFRDGLTNGNSATTAPKSEVRRLSGDISSIRDRMQSLEQQRKAFSSSKSVDVPVPPLKQRLNSLQQSVAKEEQKKPPLVALIDARQLEIMRGEEERMRQQQQKEKHSPSQTTLCAPKPAPPALIIEEPPVADTNDDSGIQEDTADELQQQQQLNAAIAALALEERQLEEAANAVNQIEAEFDELTDLHPSPLPPSPALPAVQQSLQQPTVAQVPAQAVNQAAAPPLRDMEFSVSCTNNFIEPAKISPCDVNVVAASAVSVSKSGPTPNPTSTPNMVSSSPNCNLRRKPSNEMVHHRNLLKMFKETFQNDDDLKEVCEIVTSPGQFTQIIDFSKRPSNPPIPIPTLLPTSTPIPTQIPRPLGKPPMSPKAVRLASSPKGHINPLSSPTNSGFSPPQFSINGRVEIFNSRQLDKPPTPPAPPKKTVRSEHPLKEAVPSPEVVMCAPPMTIVDPDELPKPNTVKALSNCFSQSDSKSLTSPIMSPKPLPSGRIPQITPPASPKPPKRVQLDEVDRSSGDYAPVVGQTKAIVHTPPSKINARANQTLDPLAPNDSLCLHTSSPSEIPSLKACSPNESSLFKLASSRPTSPSVDVASCQKFLNREAPKDIQLAEEDRKRMDQFAVEEMPCDKIDVTKSPQPNTGFQIVTEDLVKKCDGKNISEAVRDLDVPPSQEDIALCAGLLDCLAPAQEPICDSIDVRNGPVPATGFQDISEEEVKKCEKHNKNYVITNRPSSPIGSVRAAHSKALMDTCEQIIAEERKASSQMMKTSLPESVEKPSTPLPGRKSKIPIPKPCCISASGTDSISRAGYVPTAPSHLSGSAQQPLIARTHVVETEIKVKEISPPSIPKTPEQTQLHASPTKEKKAKNIFDFLRRNFGHQEEPQHHSTLNETLEKKVVLTSTKSGVDVVNADEFVRVDNSKFYLASELEDVPVPPPLPKTPAPVNIEIRKKITTNEILEENTTEQALTQEISDLLDDEIMKLEN
What are the official names of this protein?
Uncharacterized protein CG43427.
Protein: GRPE_RHILW
Sequence: MTDDTTKNGPDATAADAAADAAAYVENDIAQEEAPQPDALELLKAENGELRDRYLRLAAEMDNLRRRTEREVKDAKSYSVAGFARDMLAVSDNLRRALDAIPAEVKDAADAGLSTLIEGVEMTERAMLSALERHGVRKLEPVGQKFDPNFHQAMFEVPNPDVPNNTVVQVVQAGFSIGERVLRPAMVGVAKGGPKAAEAETNSVFDEKDA
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGC_PSEP1
Sequence: MIKVGIVGGTGYTGVELLRLLAQHPQAEVAVITSRSEAGVAVADMYPNLRGHYDGLAFSVPDSKALGACDVVFFATPHGVAHALAGELLAAGTKVIDLSADFRLQDAVEWGKWYGQPHGAPELLKDAVYGLPEVNREKIRQARLIAVPGCYPTATQLGFLPLLEAGLADASRLIADCKSGVSGAGRGAAVGSLFCEAGESMKAYAVKGHRHLPEISQGLRLAAGKDIGLTFVPHLTPMIRGIHATLYANVVDTSVDLQALFEKRYADEPFVDVMPAGSHPETRSVRGANVCRIAVHRPQGGDLVVVLSVIDNLVKGASGQAVQNLNILFGLDERMGLSHAGLLP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPF_ACTP2
Sequence: MIRIGHGFDVHAFGQDRPLMICGVEVPYHTGFIAHSDGDVALHALTDALLGAVALGDIGKLFPDTDMQYKNADSRKLLIEAYRQVRAQGYKVANVDVTIIAQAPKMRPYIDQMRQTIADDLQCDAMQVNVKATTTEKLGFTGRGEGIACEAVALLIKQ
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: CLPX_AERHH
Sequence: MTEKRKGEGDKLLYCSFCGKSQHEVRKLIAGPSVYICDECVELCNDIIREEIREISPKRDGSELPTPHEIRAHLDDYVIGQEYAKKVLAVAVYNHYKRLRSGSESGGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTIASVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVIEQRSVKGTGIGFGAEVKSKSAKATLSESFAKVEPEDLIKYGLIPEFIGRLPVVATLTELDEAALIQILKEPKNALTKQYAALFDLEGVELEFRDDALNAIARKAMERKTGARGLRSIVEAVLLDTMYDLPSLDGVSKVVIDETVIKGDSAPLMIYENPETQAAASE
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: SFXN5_CAEEL
Sequence: MALDETLFGYPIYPKFKLGEPRFPQDTFLGRYLHCLDVIDPRTLFASNKKLEESLELLNSFKAGTATNVPDKSLWEAQKLKSAILHPDTGEKVLPPFRMSGFVPFGWITVTGMLLPNPSWPTLLFWQWMNQSHNACVNYANRNATQPQPLSKYIGAYGAAVTAACSISGGLTYFIKKASSLPPTTRIIIQRFVPLPATSLASSLNVICMRWNELETGIQVYEKDTGKVVGVSKVAAKQAVTDTTMVRAFLPVPLLLMPPCIMPYLERFKWVTKTQVRHIFVNAIVCTLSFAVSLPVALALFPQESAISREQLEPELQQKTKNSLLYYNKGL
What is the function of this protein?
Mitochondrial amino-acid transporter.
What are the official names of this protein?
Sideroflexin-5.
What is the protein family that this protein belongs to?
Belongs to the sideroflexin family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: SGL_PSEPU
Sequence: MNETLKCVVRQPSVLGECPVWSVREQVLYWADILAGRLHRLDPRDGSVSTLQLPEELGCFGLREQGGFIVALRSGIYLLDAHGQLGERLAENPTGAEHSRFNDGRVDPWGRFWAGTLWQPRDRNGGQLLRVDAEHRAQVMAGDVMVSNGLAFSPDRAWAYHSDTPNHVLYRYPLDEDGQPGTRQLLREFARGSGGRPDGAAFDSAGCYWSAQFDGGRVLRLSPDGQVLDEIQLPTRWPTMVAFGGEDLRTLYITSSRENRSAEELADWPLSGCVFATRVNVPGCAEPLFAG
What is the function of this protein?
Catalyzes the hydrolysis of 6-deoxy-6-sulfo-D-glucono-1,5-lactone to form 6-deoxy-6-sulfo-D-gluconate.  Is involved in a degradation pathway of sulfoquinovose (SQ) that allows P. putida SQ1 to use SQ as the sole carbon and energy source for growth.
What are the official names of this protein?
6-deoxy-6-sulfogluconolactonase, 6-deoxy-6-sulfogluconolactone lactonase, SGL lactonase.
What is the protein family that this protein belongs to?
Belongs to the SMP-30/CGR1 family.
Protein: TIQ7_RHISA
Sequence: EDFDSQCVPTADPGPCKAYIPMWWYNVLS
What is the function of this protein?
Serine protease inhibitor.  Inhibits trypsin, elastase, plasmin and kallikrein.
What are the official names of this protein?
Kunitz-type serine protease inhibitor RsTIQ7.
Protein: FTSH_MYCS5
Sequence: MKQNIKRNWIWILIVMIVIGIILYFSIRNLFSTKVAEWSISELLNNIERAKENTTDALYFKEITVNPFTNSITGVFNNTDNTSTSFVTYTNLDLLRLSGVASDQGVISKIFTPEVFLTANNVSGSLKSVATPQPNPFLGILISSVPVLILIFVMVWIYRSQVKMMNGQGGAFGGDKGTAQIIKSDKKFTDIAGNKEPIEEISEVVDYLKNPGKYQQSGARMPHGILLGGPPGTGKTLLAKATAGEANVPFYFVSASSFVELFVGMGAKRVRQVISEARKNSPAIIFIDELDAIGRTRGSGIGGGHDEREQTLNQLLVEMDGMKENSGLLFIAATNRTDVLDPALIRPGRFDRIITVGLPDVKEREEILKLHAKGKRFESNVDFANIAKRTPGFSGAQLENVINEAVLLSIREDTKVINLYQIDEAIDRVMSGPAKKSRTITKEELTMVAYHEAGHAVVGIKVPGGNKVQKITIIPRGNAGGYNLMMPENEKYNYSKADLYATIASFMGGRAAEEIIYGDNKISTGAADDIKKATSIARRMVTQFGMSDLGPIEYQSDEGSPFLGKALASNSSLSNQVNHEIELEIRKIIFTAKEQATKIIKQNIELLELIKESLLKKETIVGEEIEYIAKHMKLPPEKIEEKDLSKNSEDNNLDSLIEKTSKKE
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: CHEB3_GEOSL
Sequence: MRKIRVVVIDDSAYSRRAITKMLESMPEVEVIGYATDGEEGIRKIIDLKPDLVTLDLEMPRMDGFTLLRIVMEYSPTAVIVISSRSEDEKVFRALELGAVDFVAKPTKGVSEEILTIREDLHRKVRGVIHLNLAGIVRREREQERASVAAGRRTSGSAPYAKAAVRTESTAPRPAGRLEVVAIGASTGGPPALQRILCALPGAFPQAVVVSQHMPAGFTRTFAERLNRLSPLEICEAADGDEVRAGRVLIAPGGHNMVFERQGSEVRARIVKPGTDDRYVPSVDAMLLSCAEVFGPRTLGVVLTGMGNDGSKGVAAINRAGGQTLAEAEETAVVFGMPKEAIATGVVDKIVSLDRMSREIIQRCGLLSDVD
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 3.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_ECO7I
Sequence: MKPSIVAKLEALHERHEEVQALLGDAQTIADQERFRALSREYAQLSDVSRCFTDWQQVQEDIETAQMMLDDPEMREMAQDELREAKEKSEQLEQQLQVLLLPKDPDDERNAFLEVRAGTGGDEAALFAGDLFRMYSRYAEARRWRVEIMSASEGEHGGYKEIIAKISGDGVYGRLKFESGGHRVQRVPATESQGRIHTSACTVAVMPELPDAELPDINPADLRIDTFRSSGAGGQHVNTTDSAIRITHLPTGIVVECQDERSQHKNKAKALSVLGARIHAAEMAKRQQAEASTRRNLLGSGDRSDRNRTYNFPQGRVTDHRINLTLYRLDEVMEGKLDMLIEPIIQEHQADQLAALSEQE
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BTHD_DROME
Sequence: MPPKRNKKAEAPIAERDAGEELDPNAPVLYVEHCRSURVFRRRAEELHSALRERGLQQLQLQLNALGAPRRGAFELSLSAGGMGKQEQVALWSGLKRGPPRARKFPTVEEVYDQIVGILGDQQESKEQTNTQKSSKIDLPGSEAIASPKKSESTEEAQENKAPTSTSTSRKSKKEQKSEEEPTQVDSKEAKQSKELVKTKRQPKAQKKQAKASESQEEVAEDKPPSSQKRKRTTRSSTDEATAGAKRRR
What is the function of this protein?
May be involved in a redox-related process.  Required for survival and specifically for salivary gland morphogenesis.
What are the official names of this protein?
Selenoprotein BthD, dSelM.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Note=Secreted into the salivary gland lumen.
Protein: RL22_STRA1
Sequence: MAEITSAKAMARTVRVSPRKTRLVLDLIRGKNVADAIAILKFTPNKAARVIEKTLNSAIANAENNFGLEKANLVVSETFANEGPTMKRFRPRAKGSASPINKRTTHVTVVVSEK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: ILVC_GRABC
Sequence: MRVYYDRDADLNLIKGKKVAVIGYGSQGHAHVLNMRDSGVKDLVVGLRKGSSAVAKAEGEGLKVMEPAEAAAWADVVMILTPDESQADLYREHLHANLRPGAALAFAHGLNIHFNLIEPRSDIDVFMIAPKGPGHTVRGEYQKGGGVPCLVAVAQNASGNALEIALSYASAVGGGRAGIIETTFKEECETDLFGEQAVLCGGLVELIRAGFETLVEAGYAPEMAYFECLHEVKLIVDLIYEGGIANMNYSISNTAEYGEYVTGPRIVTPETKAEMKRVLEDIQSGRFVRDFMLEMKVNGASFKSIRRRNNEHQIEQVGERLRAMMPWIAKGKLVDKARN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: AROK_METTH
Sequence: MMVVKKTVRSPGSATVINAIATGRGSAFGIGLRVEAEAELIDSGVECISREGADTSLMELCTRMVIEHYGVDAGVRVVTSSDLPVASGLSSSSAASNATVMAVSSLLSDEFGLQPMEDFEMLNMAVDASLQAGVSVTGAYDDASASFYGGLTVTDNMERRIILREPMENQKVLIYMPDRKSLTAQSDVPRMKLLAPWVDMAFREVLDGRVHSALTLNGILYCASLGFDPGIALDALEAGALAAGLSGTGPSFVALTHEDSEADIIDAWENLEGDVLVTSVDNEGTRVLE
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.