PharMolix/UniProtQA huggingface dataset:
Protein: ATAD3_XENTR
Sequence: MSWLFGLNKGQQGPPSVPGFPEPPSPPGGSGDGGDKNKPKDKWSNFDPTGLERAAKAARELDQSRHAKEALNLAKVQEETLQLEQQSKIKEYEAAVEQLKNEQIRVQAEERRKTLNEETKQHQARAQYQDKLARQRYEDQLRQQQLQNEENLRRQEESVQKQEAMRKATVEHEMELRHKNEMLRIEAEARARAKVERENADIIRENIRLKAAEHRQTVLESIKTAGTVFGEGFRAFISDWDKVTATVAGLSLLAVGIYTAKNATGVAGRYIEARLGKPSLVRDTSRFTVAEAVKHPVKISKRLLSKIQDALEGVILSPKLEERVRDIAIATRNTKANKGLYRNILMYGPPGTGKTLFAKKLAMHSGMDYAIMTGGDVAPMGREGVTAMHKVFDWAGTSKRGLLLFVDEADAFLRKRSTEKISEDLRATLNAFLYRTGEQSNKFMLVLASNQPEQFDWAINDRIDEIVHFDLPGLEERERLVRLYFDKYVLQPASEGKQRLKVAQFDYGKKCSDLAQLTEGMSGREISKLGVAWQAAAYASEDGILNEAMIDARVADAIRQHQQKMEWLKAEGKENAAKESGKNPLQPLLEGTPV
What is the function of this protein?
Essential for mitochondrial network organization, mitochondrial metabolism and cell growth at organism and cellular level.  May play an important role in mitochondrial protein synthesis.  May also participate in mitochondrial DNA replication.  May bind to mitochondrial DNA D-loops and contribute to nucleoid stability.  Required for enhanced channeling of cholesterol for hormone-dependent steroidogenesis (By similarity).
What are the official names of this protein?
ATPase family AAA domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein. Mitochondrion matrix, mitochondrion nucleoid. Note=In the mitochondrial inner membrane, enriched in sites with the potential to form contacts with the outer membrane. The N-terminal domain interacts with the inner surface of the mitochondrial outer membrane and the C-terminal domain localizes in a specific matrix compartment, where it is associated with nucleoids (By similarity).
Protein: MIAA_LEIXX
Sequence: MQLYRGMDIGTAKLPPGEWRGLPHHLFDVLDVTDEAAVARYQPEARRVVQEIRERGSTPILVGGSGLYVSSVVFDFRFPGTDTALRARLEAELAAQGPGTLFQRLLARDPEAAKRIGSSNGRRIVRALEVAELTGAAVSGALPEEPKPWVPVRVLGLAAPREELVQRLDARVERMWAEGLLAEVEGLIPLGIERSVTARRAIGYAQALAELTGELTRSQAQAQTQRLTRRYARRQLSWFKRYPGIHWLDYDDPQLVAAALARL
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: RL20_LEPIC
Sequence: MPRAVNGTIHKNRRRRILKDAKGFRGARSKLYRTAKSAVMKAGQWAYRDRRAKKRDFRKLWIIRINAAARENGLSYSVFMNSLKKLGIHMDRKSLAELAFNDREVFNSLVEKIKVAG
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: FK130_ARATH
Sequence: MQSQTNPNPSLPDDLILSCVARVSRLYYPALSLVSKSFRSLIASPELYKTRSLLDRTESCLYILYCTSNTWHEGPRLRVKLMSCTACVLDEKIYVSGRCKDGDSMTFQVFDTNTQTWDPLSVPCSETKHDFHYKIVRFDGKLHLVSYKGVDAYNSKEGRWDLVTPSIEHNKYLYDCYRNIGNVWYTIVKGDISTSVWWYHSEEREWRDLKGMVGLPKFPIDACLRMVDYGGKMAVLWDDYLPGRRKKMIWCAEIALERRGSLEIWGKVEWFAHVLTVPRQYEFVKVLAATL
What are the official names of this protein?
F-box/kelch-repeat protein At5g38670.
Protein: SYFB_BUCAP
Sequence: MKFNENWLREWINPKITSVSLRNQIVESGIEIESIHEFNPIFDGFLVGKIVECINPCKGNNLKILKVDVGYKKLLNIVCGASNCRNNIKVVVATIDSILPNGSKIKIKKIKEKLSEGMICSFFELGLFNFCKDIIELPEDIPIGKKINDLFLLKKDTFIKVAVTPNRPDGLSILGIARNIAAINNLKKIRLKKRILPTTIEDQFPITINTEKQSVNYFGRIIQNVNLNVDTPFWMKKKLFFCDLLSDNIIENILNYILIEIGQPLNILNADKIDDVIEIRMAIKKEFLILKNDTRIVLDKDILVFSDKTKILFIPGNINNSDLEPNKNTKNIFLTSYLVDKKSILNILKKIDSNNILDYYSHGVDASLQKYAIEYATYLIVKICGGKIGPINTKKSNFNSLSCSNKIKLYHQNFNKCIDSFVDSSIISNILLCLEYKVNFHKKYWYVFPPSWRFDILIEEDVIGDILRIYNYNNIPLTPLKQNYYFNSKNKDLKSPLLDEAAVLLINRGYYEIITYSFINPSLQDDIIPNNNQILISNPISKDFSSMRLSLWPGLLKTVSYNKNRQQESMRFFERGLCFSIDESQILGIRQEMFLGGVISGFYSKENWFSVRRKVDFYDLKGDLESLLEVICGLNKFEIRHQNILGLHPEQSAKIYLDNKYIGSLGKIHPKIEKKLNLYNSTFLFELSLNYISKLKFYNTEEISKYPTSRRDIAILVSKDIPFLDIITVCKDFFVNKKVEINLFDVYSCKEFDNRKKSLGISFVFQNFKKNLKENEVNLMLHDCIKILKKKFQVVLRK
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_FINM2
Sequence: MMKINSYAKINLSLDVLDLREDGYHNIDTIMNLIDLHDVIEINRNNTNELKLSSNNSNFPTDKTNLIYKIFENLKKFRKINCSYDVFVDKQIPISAGLAGGSSNACEFLMYVNDDLSLNLSNQEIKEICRLTGADTFYFTSKKCVRATGIGNEFVRLSDFSNKNIIIVNNGMSISSKDVYDNLKESNGGLGKITVAIDSRDYETFYRKAFNTMESVSERLVEEISDIKEQLNNLGCDLSLMSGSGPTVFGIFENYNDYENCYSKLKDKYKYVFKTKTL
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: ARGJ_BURL3
Sequence: MAVNFPSIDPAQLHPVAGVTLGWAEANIRKPNRKDVLVISVDESATVAGVFTENRFCAAPVIVCREHLAKVRAGGAGIRALVVNTGNANAGTGEPGLVNARETCAELARLAGIEPAQVLPFSTGVILEPLPIDRLKAGLPAALANRKAANWFDAAQAIMTTDTLPKATSRQVTIDGHTVTLTGISKGAGMIKPNMATMLGFLAFDANVAQPVLDTLVKEVADRSFNCITIDGDTSTNDSFILIASGKSTLPAITSTDSPAYAALRDAVTEVAQVLSQLIVRDGEGATKFMTVQVEGGKSVAECRQIAYAIGHSPLVKTAFYASDPNLGRILAAIGYAGVADLDVDKIDLYLDDVLVAKAGGRNPAYQEEDGQRVMKQSEITIRVQLGRGDAQATIWTCDLSHDYVSINADYRS
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SBI_STAAN
Sequence: MKNKYISKLLVGAATITLATMISNGEAKASENTQQTSTKHQTTQNNYVTDQQKAFYQVLHLKGITEEQRNQYIKTLREHPERAQEVFSESLKDSKNPDRRVAQQNAFYNVLKNDNLTEQEKNNYIAQIKENPDRSQQVWVESVQSSKAKERQNIENADKAIKDFQDNKAPHDKSAAYEANSKLPKDLRDKNNRFVEKVSIEKAIVRHDERVKSANDAISKLNEKDSIENRRLAQREVNKAPMDVKEHLQKQLDALVAQKDAEKKVAPKVEAPQIQSPQIEKPKAESPKVEVPQIQSPKVEVPQSKLLGYYQSLKDSFNYGYKYLTDTYKSYKEKYDTAKYYYNTYYKYKGAIDQTVLTVLGSGSKSYIQPLKVDDKNGYLAKSYAQVRNYVTESINTGKVLYTFYQNPTLVKTAIKAQETASSIKNTLSNLLSFWK
What is the function of this protein?
Plays a role in the inhibition of both the innate and adaptive immune responses.  Possesses two N-terminal domains that bind the Fc region of IgG and two domains that form a tripartite complex with complement factors C3b and CFH.  By recruiting CFH and C3b, the secreted form acts as a potent complement inhibitor of the alternative pathway-mediated lysis.
What are the official names of this protein?
Immunoglobulin-binding protein Sbi.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin-binding protein Sbi family.
What are the subcellular locations of this protein?
Secreted. Cell membrane. Note=Occurs both extracellularly and associated with the cytoplasmic membrane where only the domains I and II are exposed to the extracellular media. Membrane association occurs via binding to lipoteichoic acid.
Protein: CLCB_BOVIN
Sequence: MADDFGFFSSSESGAPEAAEEDPAAAFLAQQESEIAGIENDEGFGAPAGSQGGLAQPGPASGASEDMGATVNGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQRKRLQELDAASKVMEQEWREKAKKDLEEWNQRQSEQVEKNKINNRIADKAFYQQPDADIIGYVASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRLRSVLMSLKQTPLSR
What is the function of this protein?
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
What are the official names of this protein?
Clathrin light chain B, Lcb.
What is the protein family that this protein belongs to?
Belongs to the clathrin light chain family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic face of coated pits and vesicles.
Protein: Y1413_HAEIN
Sequence: MLNQLKQSLRLNLVLTLVCLSLFLTACTNKITTKPEYIYPPQAYTAPCVKTAFTGETYGDVVIQLVKVTAERDKCASQVDHLNKWINQAKGGK
What are the official names of this protein?
Uncharacterized protein HI_1413.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: KLH10_MOUSE
Sequence: MEMESTAASTRFHQPHMERKMSAMTCEIFNELRLEGKLCDVVIKVNGFEFNAHKNILCSCSSYFRALFTSGWNNTEKKVYNIPGISPDMMKLIIEYAYTRTVPITPDNVEKLLAAADQFNIMGIVRGCCEFLKSELCLDNCIGICKFTDYYYCPELRQKAYMFILHNFEEMVKVSAEFLELSVTELKDIIEKDELNVKQEDAVFEAILKWISHDPQNRKQHISVLLPKVRLALMHAEYFMNNVKMNDYVKDSEECKPVIINALKAMYDLNMNGPSNSDFTNPLTRPRLPYAILFAIGGWSGGSPTNAIEAYDARADRWVNVTCEEESPRAYHGAAYLKGYVYIIGGFDSVDYFNSVKRFDPVKKTWHQVAPMHSRRCYVSVTVLSNFIYAMGGFDGYVRLNTAERYEPETNQWTLIAPMHEQRSDASATTLYGKVYICGGFNGNECLFTAEVYNTESNQWTVIAPMRSRRSGIGVIAYGEHVYAVGGFDGANRLRSAEAYSPVANTWRTIPTMFNPRSNFGIEVVDDLLFVVGGFNGFTTTFNVECYDEKTDEWYDAHDMSIYRSALSCCVVPGLANVGEYAARRDNFTGLALRDEVKYSASTSTLPV
What is the function of this protein?
May be a substrate-specific adapter of a CUL3-based E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins during spermatogenesis.  Required for male fertility.
What are the official names of this protein?
Kelch-like protein 10.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SARM1_CAEEL
Sequence: MLPNRKPPRPSPSFQSLNNNNQRFPLRRSLKIAQAHSLPTVPSEDAKDDDLITPELSTDFDFREIQHRYLMALQNEQDGETTSTDDAFFELDDDDDLSSPSVPGSPVDPPSISVPLPPKSAPPCPTQPAPLTNGDLYPTILSNGTPIPNGRITPALSTVSVSLIHEARLQQSLSTPCNGSEEEMHNGQVRKESEYRRFKSEGSTAGASLPAAEKTHMDELSPVDQRSTSGTARFLIQQDSVVNPSTKMSNTEQVAMMHTLKTKLSKYQAMMDKAFEEIAKVEDANIIEGCTIVRKLMRKVWNTPKVSADLANALCDYLRDRDYFDKLIKMFISPNTAACDQVRMECGKVLEECTSSANLEYIVNKSYTKKIMIVAMKLNKTPDQQRLSLSLIGNLFKHSNAVSLSLIETDVIDHIILTFKRAPECPDILRHAALALANILLYTCFEGKKKIIQKKIPEWLFFLASQADDVTRYYACIAVCTIVSVKEFEPLVRKSDTMKLVEPFLQVHDPATFARDYHKYAQGNTKEWLERLLPMLQPSRRREARSVAAFHFTLEATIKKEQNKLDVFQEIGAIQALKEVASSPDEVAAKFASEALTVIGEEVPYKLAQQVPGWTCADVQYWVKKIGFEEYVEKFAKQMVDGDLLLQLTENDLKHDVGMISGLHRKRFLRELQTLKVAADYSSVDESNLDNFLMGLSPELSVYTYQMLTNGVNRSLLSSLTDEMMQNACGITNPIHRLKLTQAFETAKHPDDVEVAMLSKQIDVFISYRRSTGNQLASLIKVLLQLRGYRVFIDVDKLYAGKFDSSLLKNIQAAKHFILVLTPNSLDRLLNDDNCEDWVHKELKCAFEHQKNIIPIFDTAFEFPTKEDQIPNDIRMITKYNGVKWVHDYQDACMAKVVRFITGELNRTTPTTKEMPSISRKTTQQRWQTTNTVSRTGPSRSIGGPRMEPPTPTFTPTGSQERATSTRRKIQPSASTTSDRN
What is the function of this protein?
Regulates expression of antimicrobial peptide nlp-29 in response to fungal infection or physical injury.
What are the official names of this protein?
NAD(+) hydrolase tir-1, NADase tir-1, Neuronal symmetry protein 2, SARM1 homolog, Sterile alpha and TIR motif-containing protein tir-1.
What is the protein family that this protein belongs to?
Belongs to the SARM1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_FRATN
Sequence: MGQKVNPNGIRLGYIRDWRSTWYADSSSYATKLNEDIKVREFLHKKLAAAAVSKIQIERPAQNAKITIHTARPGIVIGKKGEDVEKLRAEVHKLMGIPVQINIEEVRKPEIDAKLVAESVAQQLEKRVMFRRAMKKAMQAAMKSGAKGIKIMVSGRLGGAEIARSEWARDGRVPLQTFRADVDYATAEALTTYGVIGVKVWIYKGEILPGQIAEKKNNKKGAK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: MURA1_STRR6
Sequence: MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQNVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVLGPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHIYMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETITITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVEVIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFENRFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETVVGKLVHLDRGYYGFHEKLAQLGAKIQRIEANDEDE
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1, Enoylpyruvate transferase 1, UDP-N-acetylglucosamine enolpyruvyl transferase 1, EPT 1.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_XANCB
Sequence: MTTFTAKSETVQRDWYLVDAAGKTLGRLSTELARRLRGKHKPVYTPHVDTGDYLVVINAEKIVVTGNKLKDKKYHRFTGYIGNLKTESLEQALQRHPERVIEIAVKGMLPKGPLGRTMYRKLKVYSGAEHPHAAQQPQVLDI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: PPK27_SCHPO
Sequence: MSEKKHSCEEKSLQLYPLSNKIRHVNPNISALPSETDISESLTNDLTKLEISNYAPFNRDLETFSDLIFGLTNIQKKSLYSLQLGRSRGYALYSDENEKYLWSINTKITSTEQREVLLVKSNNKKFDTSIVLKHTHLSSKSQNEKKARVKVFRQEIWALKTLSHPCVVQLLNYYVSSAELILVENYCMGGDLYHYTKKHHSDFSLEFVGRIFSELVHTVAYLHSKCLIHRDLKLENILLTQPYNVIKTIDNWKNYPNALIQISDFELSIFVDSKNHLVQSSCGSQEYAPPEVYMGIAHDGFRADAWSLGIVLFALLEGRLPFDSYPTLDPENVRIKRYVQRLVRCDYTWHLCKSPFKRSTGNTNDNDDPSWRFRLFVKKLLKNRDQRSTPTELLKDFNKHGNFTLPLLENVTI
What are the official names of this protein?
Serine/threonine-protein kinase ppk27.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRE2A_ORYSI
Sequence: MERGEGRRGDCSVQVRKKRTRRKSDGPDSIAETIKWWKEQNQKLQEENSSRKAPAKGSKKGCMAGKGGPENSNCAYRGVRQRTWGKWVAEIREPNRGRRLWLGSFPTALEAAHAYDEAARAMYGPTARVNFADNSTDANSGCTSAPSLMMSNGPATIPSDEKDELESPPFIVANGPAVLYQPDKKDVLERVVPEVQDVKTEGSNGLKRVCQERKTMEVCESEGIVLHKEVNISYDYFNVHEVVEMIIVELSADQKTEVHEEYQEGDDGFSLFSY
What is the function of this protein?
Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'.  Binding to the C-repeat/DRE element mediates high salinity- and dehydration-inducible transcription (By similarity).
What are the official names of this protein?
Dehydration-responsive element-binding protein 2A, Protein DREB2A.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: VG30_BPMD2
Sequence: MTELFNPDNPWETALLFFAVFCSVLPALLPFWFKIKKIDSQVSNSHDENLRDEITRGFKEVREDIRLLHEALNIERRERIAGDEKRCA
What are the official names of this protein?
Gene 30 protein, Gp30.
Protein: RL27_AYWBP
Sequence: MLLQLQIQLFASKKGAGSTRNGRDSHSKRLGAKLSDGQFAKAGAIIYRQRGTKIHPGFNVGRGGDDTLFAKMSGIIKFEKKHGRKKVSVYLQ
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: CEP63_MOUSE
Sequence: MEALLEGIQNRGHSGGFLTSCEAELQELMKQIDIMVAHKKSEWEGQTHALETCLDIRDRELKALRSQLDMKHKEVGILHQQIEEHEKTKQEMAMEYKEELLKLQEELSRLKRSYEKLQKKQLREFRGNTKSFREDRSEIERLTGKIEEFRQKSLDWEKQRLIYQQQVSSLEAQRKALAEQSEIIQAQLANRKQKLESVELSSQSEIQHLNSKLERAKDTICANELEIERLNIRVNDLMGTNMTILQDHRQKEEKLRESEKLLEALQEEQKELKASLQSQETFILEAKMQEKLQTTLKAVGTQQSVERPLEDCQKERKYSSPGQGVLDNVLSQLDFSHSSEELLQAEVTRLEGSLESVSATCKQLSQELMEKYEELKRMEGHNNEYRTEIKKLKEQILQADQTYSSALEGMKMEISQLTRELHQRDITIASAKCSSSDMEKQLKAEMQKAEEKAVEHKEILSQLESLKLENHRLSETVMKLELGLHEAKEISLADLQENYIEALNKLVSENQQLQKDLMSTKSELEHATNMCKKKDGEIFNPAHSRAAGFKNAELKPIHGQHRHDGIKTEQYKTGHHSPRGQTLDSIDPVARGPSPLSSHISPGSSTVSLPSNFLFEAHSLPSVLDINDVNFSDSLSDCMNDQEEFVSSGSLPTSPLGSIATRFLEEEELRSHHILERLDAHIEELKRESEKTVRQFTALV
What is the function of this protein?
Required for normal spindle assembly (PubMed:24240477).  Plays a key role in mother-centriole-dependent centriole duplication; the function seems also to involve CEP152, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication (By similarity).  Reported to be required for centrosomal recruitment of CEP152; however, this function has been questioned (By similarity).  Also recruits CDK1 to centrosomes (By similarity).  Plays a role in DNA damage response (By similarity).  Following DNA damage, such as double-strand breaks (DSBs), is removed from centrosomes; this leads to the inactivation of spindle assembly and delay in mitotic progression (By similarity).  Promotes stabilization of FXR1 protein by inhibiting FXR1 ubiquitination (By similarity).
What are the official names of this protein?
Centrosomal protein of 63 kDa, Cep63.
What is the protein family that this protein belongs to?
Belongs to the CEP63 family.
Protein: KAMA_ACESD
Sequence: MSLKDKFFSHVSQEDWNDWKWQVRNRIETVEELKKYIPLTPEEEEGVKRCLDTLRMAITPYYLSLIDVENPNDPVRKQAVPLSLELHRAASDQEDPLHEDGDSPVPGLTHRYPDRVLLLMTDQCSMYCRHCTRRRFAGQTDSAVDTKQIDAAIEYIKNTPQVRDVLLSGGDALLISDEKLEYTIKRLREIPHVEVIRIGSRVPVVMPQRITPELVSMLKKYHPVWLNTHFNHPNEITEESKRACELLADAGIPLGNQSVLLAGVNDCMHVMKKLVNDLVKIRVRPYYIYQCDLSVGIEHFRTPVAKGIEIIEGLRGHTSGYCVPTFVVDAPGGGGKTPVMPNYVISQNHNKVILRNFEGVITTYDEPDHYTFHCDCDVCTGKTNVHKVGVAGLLNGETATLEPEGLERKQRGHH
What is the function of this protein?
Catalyzes the interconversion of L-alpha-lysine and L-beta-lysine.
What are the official names of this protein?
L-lysine 2,3-aminomutase, LAM, KAM.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. KamA family.
Protein: TYY2_HUMAN
Sequence: MASNEDFSITQDLEIPADIVELHDINVEPLPMEDIPTESVQYEDVDGNWIYGGHNHPPLMVLQPLFTNTGYGDHDQEMLMLQTQEEVVGYCDSDNQLGNDLEDQLALPDSIEDEHFQMTLASLSASAASTSTSTQSRSKKPSKKPSGKSATSTEANPAGSSSSLGTRKWEQKQMQVKTLEGEFSVTMWSPNDNNDQGAVGEGQAENPPDYSEYLKGKKLPPGGLPGIDLSDPKQLAEFTKVKPKRSKGEPPKTVPCSYSGCEKMFRDYAAMRKHLHIHGPRVHVCAECGKAFLESSKLRRHQLVHTGEKPFQCTFEGCGKRFSLDFNLRTHLRIHTGDKPFVCPFDVCNRKFAQSTNLKTHILTHVKTKNNP
What is the function of this protein?
Functions as a multifunctional transcription factor that may exhibit positive and negative control on a large number of genes.  May antagonize YY1 and function in development and differentiation.
What are the official names of this protein?
Transcription factor YY2, Yin and yang 2, YY-2, Zinc finger protein 631.
What is the protein family that this protein belongs to?
Belongs to the YY transcription factor family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EFTU_BACHK
Sequence: MAKAKFERSKPHVNIGTIGHVDHGKTTLTAAITTVLAKAGGAEARGYDQIDAAPEERERGITISTAHVEYETETRHYAHVDCPGHADYVKNMITGAAQMDGGILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKCDMVDDEELLELVEMEVRDLLSEYGFPGDDIPVIKGSALKALQGEADWEAKIIELMAEVDAYIPTPERETDKPFLMPVEDVFSITGRGTVATGRVERGIVKVGDVVEIIGLAEENASTTVTGVEMFRKLLDQAQAGDNIGALLRGVAREDIQRGQVLAKSGSVKAHAKFKAEVFVLSKEEGGRHTPFFANYRPQFYFRTTDVTGIIQLPEGTEMVMPGDNIEMTIELIAPIAIEEGTKFSIREGGRTVGYGVVATIVE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_BACMK
Sequence: MTKWFNVGKIVNTHGVKGEIRVISRTDFPEERYKVGNTLYIWDEKGTDYLTVKVTSHRQHKTFDLLTLEGYNNVDEVEKLKGSLIKVPEEQLGELAEGEYYYHEIIGCNVVTEEGEALGTIKEILSPGANDVWVIKRPKGQDLLIPYIDDVVLQVNIENKLVTIHVMEGLL
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACTN_ANOGA
Sequence: MMENGGYVGQYGGEENYMEQEEEWEREGLLDPAWEKQQKKTFTAWCNSHLRKAGTSIENIEDDFRNGLKLMLLLEVISGETLPKPDRGKMRFHKIANVNKALDFIASKGVKLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDISVEEMTAKEGLLLWCQRKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRPDLIDYSKLSKDNPLENLNTAFDVAEKYLDIPRMLDPDDLINTPKPDERAIMTYVSCYYHAFQGAQQPGSTPFVIHLTKTGLSYRFFVRLFAAETAANRICKVLKVNQENERLMEEYERLASDLLEWIRRTMPWLNSRQSDSTLAGVQKKLEEYRTYRRKHKPPRVEQKAKLETNFNTLQTKLRLSNRPAYMPTEGKMVSDITNSWKGLEHAEKAFEEWLLAETMRLERLEHLAQKFKHKADTHEDWTKGKEEMLQSQDFRNCKLNELKALKKKHEAFESDLAAHQDRVEQIAAIAQELNTLEYHDCASVNARCQRICDQWDRLGALTQRRRQGLDEAERILEKIDLLHLEFAKRAAPFNNWLDGAREDLVDMFIVHTMEEIQGLIQAHDQFKATLGEADKEFNVIIGLVRDAEAIVKQEQVPGGLVNPYTTLSADLISRKWSEVRALVPQRDQTLANELRKQQNNEMLRRQFAEKANAVGPWIERQMDAVTAIGMGISGSLEEQLHRLKEYEQAVYAYKPSIEELEKIHQAVQESMIFENRYTHYTMETLRVGWEQLLTSINRNINEVENQILTRDSKGITQEQLTEFRSSFNHFDKNRTGRLAPEEFKSCLVSLGYSIGKDKQGDMDFQRILAVVDPNASGYVQFDAFLDFMTRESTDTDTAEQVIDSFRILASDRPYILPDELRRELPPDQAEYCIQRMPPYKGPNAIPGALDYMSFSTALYGESDL
What is the function of this protein?
F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures.  This is a bundling protein (By similarity).
What are the official names of this protein?
Alpha-actinin, sarcomeric, F-actin cross-linking protein.
What is the protein family that this protein belongs to?
Belongs to the alpha-actinin family.
Protein: GPMA_ECO27
Sequence: MAVTKLVLVRHGESQWNKENRFTGWYDVDLSEKGVSEAKAAGKLLKEEGYSFDFAYTSVLKRAIHTLWNVLDELDQAWLPVEKSWKLNERHYGALQGLNKAETAEKYGDEQVKQWRRGFAVTPPELTKDDERYPGHDPRYAKLSEKELPLTESLALTIDRVIPYWNETILPRMKSGERVIIAAHGNSLRALVKYLDNMSEEEILELNIPTGVPLVYEFDENFKPLKRYYLGNADEIAAKAAAVANQGKAK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: NADD_SHEON
Sequence: MRIGILGGTFDPIHYGHIRPAMEVKASLKLDKILLMPNHIPPHKNTTHSTTEQRLEMVAQVCTSLPGFELCDIEAKRDSPSYTVVTLKQLSRLYPDDELFFIMGMDSFIQLQSWHKWQQLFEFANLVVCQRPGWHLAAESRMQHELSARHASIDALSISSHPQHGHIFTVDISPQNISSTQIRSQLAMGEIPRDTLLPVTLNYIQKQRLYFS
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: SWT21_LACTC
Sequence: MNRVRKVYDTLDTFDGRDVLQSWKREGSRWLDQVENSTYQFPELESSNYERTKGRVPTEHIDLRSPIICTKLSWSQDGTSLVAVFNDYGVRQYLLPEEEGTGLVPFKRFFRAQPAVDCCIHPEYSLFNDSDACNVMLASSRDLPIQLLSLSPHAREHRPLFSYSVVNAENERFETMFSLSFSHYSGFLAGTSRNKVVAYDLNYKSPIWSSDGYGKPLRGTSARRAIISCFDSPSDSESVLRYAGTYRCDIYGIDLRTKELNFLANKQTLELKENSAGVAELLFSVNKHYLYVIKRNSQTIDVLDARSSFAKINELYLSFRIGSQKIIATLDLINGLLIGTHDGKILQWASNMVEFGGLLPRTPEGPAKDSAVSKVFDTSYAGSRINILASSPSNPHLIAGSFSPDKFEADHTAKSGLFVVDL
What is the function of this protein?
Involved in mRNA splicing.  Helps to stabilize the U1 snRNP-5' splice site interaction (By similarity).
What are the official names of this protein?
Protein SWT21.
What is the protein family that this protein belongs to?
Belongs to the SWT21 family.
What are the subcellular locations of this protein?
Nucleus.