PharMolix/UniProtQA huggingface dataset:
Protein: MDM12_YARLI
Sequence: MSIDLDWDGMINSDEIDVAEWLRSLLDKQFQQLDLPRNIRSVSITTLSLGTIPPELEIKHISDPFPEFYAEEEAAADSHYLPPLHPPQQRRSAPSTPHIHTNTTNPIDRGIASYFHPLGSAPLMSGLRTPLNIPSWATNGHTRTSSRLPLNTPIEAEIVESVRESTAPRTPEEREQQPVPEDREDDLQVLFRVKYTGDIRIGVEATLRLNYPSDDVVLLPMKLHLSHININSLAIMAYIKKSIYLSVICDLDDSDHAVARTGRERLDIIRDVKIDSEIGHHDTNGAALRNVGKVDRFIVDKIRSLLKAEIAWPSWIKVSMEDEDSDDEEGEEEGDQEDEH
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.  The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 12, Mitochondrial inheritance component MDM12.
What is the protein family that this protein belongs to?
Belongs to the MDM12 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: RPOC_STRPS
Sequence: MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPEREGLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVSHIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLREYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFYKSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELNAPGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLGKRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVERGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNADFDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEAGREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKILFNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNIIAEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISNFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSGYLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPETGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVITEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGSIQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDTDLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTRVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEGNEETTEVVVDTAVETVEETVE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: ARGB_YERE8
Sequence: MVIKLGGVLLDSEEALERLFTALVTYREKHERPLVIMHGGGCLVDDLMKKLALPVVKKNGLRVTPADQIDIITGALAGTANKTLLAWAVKHDINAVGLCLGDGNTVSVTPLDAALGHVGKAEAGSPALVQTLLAANYMPIISSIGITKDGSLMNVNADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTAQKAEQLIAQGIITDGMVVKVNAALDAARSLGRPVDIASWRHADQLPALFNGVPIGTRILA
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1703_LACJO
Sequence: MNNQKGLSVKSVVAIGIGAAIYVILARFTSIPTGIPNTNIEIVYPFLALLATIYGPVVGFSVGFIGHALSDFLMYGQTWWSWVLATAVLGLIIGLYGMRLDLENGVFTTKQMIGFNIVQIIANVVSWLIIAPVGDILIYSEPQNKVFLQGATATITNSISILILGTILLKAYAATKVKKGSLRRD
What are the official names of this protein?
UPF0397 protein LJ_1703.
What is the protein family that this protein belongs to?
Belongs to the UPF0397 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LIN23_CAEEL
Sequence: MSSPHRASTTQQLADLSLTEGEHDEGKPLSIDYLQGHEGLIEEVLKWSEHEQLDFMDKIVHRLSHYQLGKVDNFIRPMLQRDFISNLPAHLVELILFNVNSDSLKSCEEVSTSWRCALARGQHWKKLIEKNVRSDSLWWGLSEKRQWDKFLNISRDMSVRRICEKFNYDVNIKRDKLDQLILMHVFYSKLYPKIIRDIHNIDNNWKRGNYKMTRINCQSENSKGVYCLQYDDDKIVSGLRDNTIKIWDRKDYSCSRILSGHTGSVLCLQYDNRVIISGSSDATVRVWDVETGECIKTLIHHCEAVLHLRFANGIMVTCSKDRSIAVWDMVSPRDITIRRVLVGHRAAVNVVDFDDRYIVSASGDRTIKVWSMDTLEFVRTLAGHRRGIACLQYRGRLVVSGSSDNTIRLWDIHSGVCLRVLEGHEELVRCIRFDEKRIVSGAYDGKIKVWDLQAALDPRALSSEICLCSLVQHTGRVFRLQFDDFQIVSSSHDDTILIWDFLDAPPSGLPSSTNRATLPELPNQAAVARAQMLFEMAARREIERRDREVVEEPALRPRANAARRHNADIAAAAAAAEAARGAGDNDESSSEEDLDRVDQVNNPNVAGPAPPQPHNQNHRRRQPRPELPVRLMQEMAAFDNMRRQQNNMDHLGGGDVDEEMPDGGP
What is the function of this protein?
Functions cell autonomously to negatively regulate cell cycle progression.  Required to restrain cell proliferation in response to developmental cues.  Probably recognizes and binds to some proteins and promotes their ubiquitination and degradation (By similarity).
What are the official names of this protein?
F-box/WD repeat-containing protein lin-23, Abnormal cell lineage protein 23.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YGY9_YEAST
Sequence: MKFLKNKAPANLVDNGRFVEAITCNKVKPNPSCVSNCLKFLSEVLAVEAITDSARNLATVSKSDILLFSLLQLSSNKQSGSSLPLFDLVFILLSTFFLFHNPCN
What are the official names of this protein?
Putative uncharacterized protein YGL239C.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MTEF2_MOUSE
Sequence: MPWRLPTGHQLCRLCLLRKPRPALKIKPSSACVTYGTDSQSDKENKRTVEKLSACSVDIRKIRRLKGWVLLEEETYVEEIANILKELGANKTVIASILERCPEAIICSPAAVNTKRKLWQMVCKNEAELVQLIEQFPESFFTVKNQENQKLNVQFFQELGLRNVVISRFLTTASSIFHNPVENNKQMIGVLQESYLNLGGSEANAKVWLLKLLSQNPFIVLHSPRAVGETLKCLQGQGFTDSEVLQLLSKLKGFLFQLQPGSIQNSISFTKTTFECTDYDLRQLVVKCPALLCYPASVLEERIQALLKEGISIAQIRESPMVLELTPQIIQYRIRKLNSLGYGIKDGHLASLNGTKKEFEANFSKMQAKQGRPLFNPVASLKVEE
What is the function of this protein?
Binds mitochondrial DNA and plays a role in the regulation of transcription of mitochondrial mRNA and rRNA species.
What are the official names of this protein?
Transcription termination factor 2, mitochondrial, Mitochondrial transcription termination factor 2, mTERF2, mTERF domain-containing protein 3, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the mTERF family.
What are the subcellular locations of this protein?
Mitochondrion matrix, mitochondrion nucleoid.
Protein: MFSD3_RAT
Sequence: MHGKLLPLAGLYLVQGLPYGLQSSLLPILLRARGLSLTRVGLTKGLYAPWLLKLAWAPLVDRRGTPRVWLTFSTVCLGLVCGLLAVLPPPQAGQTGLPTTVMGLLLLLNLGAAVQDVALDTLAVQLLEPKELGPGNTVQVVAYKLGSALAGGGLLVFFPTLSWPLLFLLLTATYWLAAALAWAAPALGRLSRPQVSEHTPHTSYLLQDLLAVPGTLWTAGFVLTYKMGEQGAGSLFPLLLLDHGASASDLGLWSGLGAATCSIAGSSLGGALLARHCSHPRQPLKLLRSVLQLRLGGLACQTALLLHLNTPGASLDPGTVMRGAALLSLCLQQFLGGVVTTATFTVMMHCSQLAPRALQATHYSFLATLELLGKLLPGTLAGVLADGLGPRLCFAAFLVLSALPVLDLRLAPSNLT
What are the official names of this protein?
Major facilitator superfamily domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL14_GRAFK
Sequence: MVQQESRLKVADNTGAKEVLAIRVLGGTKKRYASVGDKIVVSVKEATPNGSIKKGAVSTAVVVRTRKEVRRPDGSYIRFDDNACVLLGPQGEMRGTRVFGPVARELRDKQFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: BETA_PSEU2
Sequence: MTTQSEYDYIIIGAGSAGNTLAARLTEDAGVTVLLLEAGGPDYRLDFRTQMPAALAFPLQGRRYNWAYETEPEPHMNNRRMECGRGKGLGGSSLINGMCYIRGNAMDYDGWAKEPGLEDWSYLDCLPYFRKAETRDIGPNDYHGGEGPVSVTTPKAGNNPLFHAMVEAGVQAGFPRTDDLNGYQQEGFGPMDRTVTPNGRRASTARGYLDEAKKRSTLTIVTHALTDRILFEGKRAVGVAYLVGDSDTRIQARARKEVLLCGGAIASPQILQRSGVGPAEVLNKLDIPVVHDLPGVGQNLQDHLEMYLQYACTQPVSLYPSLKWWNQPAIGAEWMFLGTGIGASNQFEAGGFIRSSEAFEWPNIQYHFLPVAINYNGTKGVQEHGFQAHVGSMRSPSRGRVQVKSKDPREYPSILFNYMASEQDWQEFRDGIRLTREIMQQPALDPYRGREISPGIDVQSDEALDQFVREHAETAYHPSCSCKMGTDEMAVVDGQGRVHGLQSLRVVDASIMPIITTGNLNAPTIMIAEKIADKIRGRQPLPRSTADYFVAGDKPARGKPLREISHQA
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
What are the official names of this protein?
Oxygen-dependent choline dehydrogenase, CDH, CHD, Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: BROX_MOUSE
Sequence: MTHWFHRNPLKATAPVSFNYYGMITGPPASKICNDLRSARTRLLELFTDLSCNPETMKNAADLYFSLLQGFINSVGDSTQESKLRYIQNFKWTDTLQGHVPSAQQDAVFELISMGFNVALWYTKYASRLAGKENITEDEAKEVHRSLKIAAGIFKHLKESHIPKLLTPAEKGRDLEARLIDAYIIQCQAEAQEVTIARAIELKHAPGLIAALAYDTASFYQKADHTLSSLEPAHSAKWRKYLHLKMCFYTAYAYCYHGQTLLASDKCGEAIRSLQEAEKLYAEAEALCKEYGETKGPGPTAKPSGHLFFRKLGSLVKNTLDKCQRENGFIYFQKIPTEAPQLELKANYGLVEPVPFEFPPMSAHWTPEALAAFDLTKRPKDDSVKPKPEEDVKPVKEPDIRPQKDTGCSVS
What is the function of this protein?
Nuclear envelope-associated factor that is involved in the nuclear envelope ruptures during interphase (NERDI) repair, where it is locally recruited by CHMP5 and reduces cytoskeletal stress through its action on SYN2 to help reseal the ruptured membrane.
What are the official names of this protein?
BRO1 domain-containing protein BROX, BRO1 domain- and CAAX motif-containing protein.
What is the protein family that this protein belongs to?
Belongs to the BROX family.
What are the subcellular locations of this protein?
Membrane; Lipid-anchor.
Protein: CTU1_ASHGO
Sequence: MYIPPSDPRRPAKVTAGQLCELCHARKALVKRPKNLQKVCKLCFFHVFETEIHNTIMENKLFQRGERVAVGASGGKDSTVLAYILKLLNERHDYGLEIVLLSIDEGIVGYRDDSLATVKRNQEQYGLPLKIVSYKDLYDWTMDEIVACAGMRNSCTYCGVFRRQALDRGAAMLDIHHVVTGHNADDMAETVLMNILRGDVARLEKSTAILTQSSGSPVKRSKPFKYAYQKEIVLYAHYKKLDYFSTECSYAPEAFRGTARELMKNLEAVRPSCIIDIIHSGEALRLRPRPKKRAPPPGSVEIRADGSASLFRNEGFVDGNRCERCGYLSSNRICKACMLLEGLEKNRARVQIADDTSTEGAARLTRTLEKLHF
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation.  It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.  Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation.  May also be involved in protein urmylation.
What are the official names of this protein?
Cytoplasmic tRNA 2-thiolation protein 1, Cytoplasmic tRNA adenylyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYNI_ASPNC
Sequence: MEPILHIQGDAHSSLTPLIFIHAVSGLAWPYMALGNLSNTSDPARSRPVYGISSPVYSSELQPHGPYLLGGWSMGGMIAVKMAEILQAKKETVQQVILLDSINPEKYPAFVNEEEHRIIADGLFTNVCQAMGMADLADDSDDEDNRSDASDASDDGSTMSDEEEEDDNLHRLFSTMRRHIHASTLSISSTEPGKLLPPNSVCHTSVTLVKCTQLSETVPALFSARQRCIRRCALHPTLQWRPQNFDRFRTLLIDARHDSLFDEEHVEEVTSMLRQILESC
What is the function of this protein?
Thioesterase; part of the gene cluster that mediates the biosynthesis of pyranonigrins, a family of antioxidative compounds (PubMed:24106156).  The first step of pyranonigrins biosynthesis is performed by the hybrid PKS-NRPS synthetase that condenses 6 malonyl-CoA units to an acetyl starter unit, to form a 1,3,5-trioxotetradecane-6,8-dienyl-ACP (PubMed:24106156).  The enoyl reducrase (ER) domain of pynA is likely to be functional during the first two rounds of polyketide chain extension, to generate the saturated C-C bonds of the alkyl side chain (Probable).  PynA subsequently forms the amide bond between the acyl chain and L-serine (PubMed:24106156, PubMed:26414728).  Although pynA has a terminal reductase domain, it appears to require the thioesterase pynI for the release of the straight-chain intermediate from pynA via the formation of a tetramic acid pyranonigrin J (PubMed:26414728).  The methyltransferase pynC then coverts pyranonigrin J to pyranonigrin I via N-methylation (PubMed:26414728).  The FAD-dependent monooxygenase pynG catalyzes an epoxidation-mediated cyclization to form the dihydro-gamma-pyrone moiety, followed by pynD-catalyzed oxidation of the alcohol to the ketone and enolization to yield the characteristic tetramic acid-fused gamma-pyrone core of pyranonigrin H (PubMed:26414728).  Pyranonigrin H is substrate of pynH for dehydration-mediated exo-methylene formation from the serine side chain to produce pyranonigrin E, before the oxidase pynE reduces the exo-methylene of pyranonigrin E into a pendant methyl to form pyranonigrin G (PubMed:26414728).  The FAD-linked oxidoreductase pynB performs the reverse reaction and converts pyranonigrin G back to pyranonigrin E (PubMed:26414728).
What are the official names of this protein?
Thioesterase pynI, Pyranonigrin biosynthesis cluster protein I.
What is the protein family that this protein belongs to?
Belongs to the AMT4 thioesterase family.
Protein: QOX2_STAAN
Sequence: MSKFKSLLLLFGTLILLSGCSNIEIFNAKGPVASSQKFLILYSIVFMLVICFVVLGMFAIFIYKYSYNKNAESGKMHHNAIIETIWFVIPIIIVAALAIPTVKTLYDYEKPPKSEKDPMVVYAVSAGYKWFFAYPDEHIETVNTLTIPKDRPVVFKLQAMDTMTSFWIPQLGGQKYAMTGMTMNWTLEASQTGTFRGRNSNFNGEGFSRQTFKVNAVSQKDYDKWVKEVKGKKTLDQDTFDKQLLPSTPNKALEFNGTHMAFVDPAADPEYIFYAYKRFNFELKDPNFTSEENMFKDVSDKPLIPARKAQITNANYKRHGMKLMILGNDEPYNNEFKKDESKNAKEMKKISKDAQDQDNDDHGGGH
What is the function of this protein?
Catalyzes quinol oxidation with the concomitant reduction of oxygen to water.  Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I (By similarity).
What are the official names of this protein?
Probable quinol oxidase subunit 2, Quinol oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ACPH_ECO8A
Sequence: MNFLAHLHLAHLAESSLSGNLLADFVRGNPEESFPPDVVAGIHMHRRIDVLTDNLPEVREAREWFRSETRRVAPITLDVMWDHFLSRHWSQLSPDFPLQEFVCYAREQVMTILPDSPPRFINLNNYLWSEQWLVRYRDMDFIQNVLNGMASRRPRLDALRDSWYDLDAHYDALETRFWQFYPRMMAQASHKAL
What is the function of this protein?
Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP.
What are the official names of this protein?
Acyl carrier protein phosphodiesterase, ACP phosphodiesterase.
What is the protein family that this protein belongs to?
Belongs to the AcpH family.
Protein: QUEC_ECODH
Sequence: MKRAVVVFSGGQDSTTCLVQALQQYDEVHCVTFDYGQRHRAEIDVARELALKLGARAHKVLDVTLLNELAVSSLTRDSIPVPDYEPEADGIPNTFVPGRNILFLTLAAIYAYQVKAEAVITGVCETDFSGYPDCRDEFVKALNHAVSLGMAKDIRFETPLMWIDKAETWALADYYGKLDLVRNETLTCYNGFKGDGCGHCAACNLRANGLNHYLADKPTVMAAMKQKTGLR
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: XYLA_BURVG
Sequence: MSYFEHIPAIRYEGPQSDNPLAYHHYDPAKRVLGKTLAEHLRIAVCYWHTFVWPGHDMFGQGTFVRPWQQPGDPLERARMKADAAFEFFSKLGTPFYTFHDTDVAPEGDNLREYTANFARMVDYLGERQQASGVRLLWGTANLFSHPRFAAGAATNPNPDVFAWAATQVRHALDATHRLGGENYVLWGGREGYETLLNTDLKRERDQFARFLSMVVEHKHRIGFNGALLIEPKPQEPTKHQYDYDVATVHGFLVQYGLQDEIRVNIEANHATLAGHSFHHEIANAFALGVFGSVDANRGDPQNGWDTDQFPNSVEELTLAFYEILRHGGFTTGGMNFDAKVRRQSVAAEDLFYGHVGAIDVLALALERAAVLVENDRLDALRRQRYAQWDDAFGRKILSGGYTLQSLADDALARGVNPQHVSGAQERLENIVNQAIYALR
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIBU_LACLN
Sequence: MSKTRRMVLIAMLAALSTILLLPILQFPLLPGIDFMKVELSIIPVLIGVFTLGLGDGFIILFIRSVLWYLLFNQGPSTWIGVPMNFVALGIFMAIVWFFTKKKFSIKNYTVGIVLATIASVLVMMVLNVFYALPLYRLAAGFDVDKIFAGATHLFNMGSLSVTLNPTYLLTVVLPFNALQYIIFALVFGLIVTVFKKNKVVKFYNA
What is the function of this protein?
Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.  The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins (By similarity).  Mediates riboflavin uptake, probably also transports FMN and roseoflavin.
What are the official names of this protein?
Riboflavin transporter RibU, Riboflavin ECF transporter S component RibU.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL22_BURP6
Sequence: MEVKAIHRGARISAQKTRLVADQIRGLPVDKALNVLTFSPKKAAGIVKKVVLSAIANAEHNEGADIDELKIKSIYVDKAASLKRFTARAKGRGNRIEKQSCHITVTVGN
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: PLSY_LIMRD
Sequence: MFFEIIGMIIIAYLLGSIPTGLWIGKYIYHKDIRKLGSGNIGTTNTFRTLGFKAGVVVLFIDILKGTLAASQPYFLGISGTVNPLLIGLFASLGHTVSIFDNFHGGKAVATSAGILLAYNPLLFVVACLIFIFVLCLTSMVSAASMVGISAIFIIALFIHAWILAIVAGILTGVVFYRHRSNIHRILSGKESMVSFGLGYYLREKKQNK
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VELB_FUSO4
Sequence: MNSAYHSPDMSQRIPGPAYSSSAPPPPIHTYQQHQHPPPPLPPPSQHHHSSHPPLPPPPSAPHPHHQHPPPPPPSHSLSSHQHHSQPPHHQSQLPPYAPAPYQQPQPSQYPRPHPHQQHAPSPSQHDEPPPPPPFSGPSPTDHQKDSEYVPPSYSKIEEGSGWKYSLDVKQQPVRARMCGFGDKDRRPITPPPCVRLVIINTETGKEVDYNSLDHAMFVLSVDLWNHDGTKEVNLVRSSTGTGAMASSSTYTYSSLEPGTPSYQQQSLPPSRESGYGQSQGLNYGQDYPPPVQQSYGQAPSYPPSSSYGPPQQYYPRHSGYSAEPSAPPPGAPFRNGYGQDQNALTRMAVVGGQPQGMFTRNLIGSLAASAFRLEDTEGQSGIWFVLQDLSVRTEGTFRLRFSFVNVGRPGGQGTNVNQGRAPILSSCYSESFHVYSAKKFPGVCESTPLSKKFANQGIKIPIRKDANIKGEGDEEMYDQN
What is the function of this protein?
Component of the velvet transcription factor complex that controls sexual/asexual developmental ratio in response to light, promoting sexual development in the darkness while stimulating asexual sporulation under illumination (By similarity).  The velvet complex acts as a global regulator for secondary metabolite gene expression (By similarity).  Component of the velB-VosA heterodimeric complex that plays a dual role in activating genes associated with spore maturation and repressing certain development-associated genes (By similarity).  The velB-VosA complex binds DNA through the DNA-binding domain of vosA that recognizes an 11-nucleotide consensus sequence 5'-CTGGCCGCGGC-3' consisting of two motifs in the promoters of key developmental regulatory genes (By similarity).  Controls the biosynthetic gene cluster for beauvericin, a depsipeptide mycotoxin that functions as a virulence determinant (PubMed:23106229).  Regulates also chromatin structure and transcription of siderophore biosynthetic genes and is required for infection of tomato plants (PubMed:23106229).
What are the official names of this protein?
Velvet complex subunit B.
What is the protein family that this protein belongs to?
Belongs to the velvet family. VelB subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Nuclear localization is mediated by veA (By similarity).
Protein: LOLB_HALHL
Sequence: MTGRWSPRLLAGLLAALVLSGCALLVPEDEREAQYEAFLEERAELRDWSVAGRAALRAEGEAVSLSLRWEQRGEVYTINLSGPFGAGAVRIEGQPGRVTLRDGAGQSATAQSPEELLAAQTGHQLPVTALRDWIVGRPADGLEVDELSLDRVGRPDRLEQAGWRVDFQGWTDVDGVDLPSRVDLTRGSTQMRVALSGWSRSDD
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: TI214_LEPVR
Sequence: MMVFQSFILGNLVSLCMKIINSVVVVGLYYGFLTTFSIGPSYLFLLRARVMDEGEEGTEKKVSATTGFIAGQLMMFISIYYAPLHLALGRPHTITVLALPYLLFHFFWNNHKHFLDYGSTTRNEMRNLRIQCVFLNNLIFQLFNHFILPSSMLARLVNIYMFRCNNKMLFVTSSFVGWLIGHILFMKWVGLVLVWIQQNNSIRSNVLIRSNKYKFLVSELRNSMARIFSILLFITCVYYLGRMPSPIFTKKLKGTSETEERGGTKQDQEVSIEEAPFPSLFLDGNKENSNLEFFKIKKKEDYCLWFEKPFVTLVFDYKRWNRPNRYIKNDKIENTVRNEMSQYFFYTCQSDGKERISFTYPPSLSTFFEMIQKKIPSFTREKTASTQVSTYWSLINEEKKENLKKELLNRIEALDKGWSVENILEKTTRFCHNETKKEYLPKIYDPSLHGISRGRIKKLPPFKIITETYITNNIGGSWINKIHGILLKINYQKFEQTLEKFNRKSLSIEKKLYFFSEPQEEKIHSEEELKIFKFLFNVVRTDSNDQTLNRTNFIDFHEITKKVPRWSYKLIGELEELEGENEDNVPMEPGIRSRKGKRVVIFTDNQNSDQNDEMALIRYSQQSDFRREIIKGSMRSQRRKTVIWEFFQAKVHSPLFFDRIDKLFLFSFDIRGLKKKILRNFMWKNKKKKKIDKKEEEQSKIEEKRRIEIAETWDSFLFAQIIRGFLLITQSILRKYIILPLLIIMKNSVRMLLFQIPEWSEDLKDWKREMHVKCTYNGVQLSETEFPRNWLTDGIQIKILFPFYLKPWHKSKFQSSQKARLKKTKAKGEKNAFCFLTVWGMETELPFGSAQRKPSFFQPISKELKKRIKKLKTKPFLVLGIFKERATICLKVAKEIKNWILKNSLFIKVKRKNLSKPNKIPVFGPREIFELNETKKDSIMSNQMIYELSVQNKSMEWRNSSLSENKIKNLIDRIKTIRNQIEEISKEKENLTNSCNKLRYDSKIIESAKRIWQIFKRKNTRFIRKSIFFIKFCIEQLSIAIFLGISNIPRITTQLFFESTKTILNKYIYKNEEKVEKINKKKNTIYFISTIKNLISNKKKISYDLCSLSQAYVFYKLSQIQVSNFSKLKAVLEYNICITSFFVKNQIKDFFQEQGIFHYELKDKTFFNSEVNQWKNWLRSHYQYNLPQVAWARLVTQKWKTKITQDSLVLNPSLTKEDSYEKKKFDNSKKDNFFEANLLLNPKHNLKKDSIYNLFCYKSINSTEKKFDMSIGIALDNCLVSCFLEKYNIRGTGEIRHRKYLDWRILNFWFTKKVNIEPWVDTKSKKKYINTKVQNYQRIDKITKTSLANQKRNFFDWMGMNEEILNPCITNFEFFFFPEFLLFSSTYKTKPWVIPIKLLLFNFNENINVNKKITRKKTSFIPSNENKSLLFYNLNNEEKELADEVELESDNEKQINPESALSNQEKTIQEIYAESKKKKRQNKKQSKSNTEVELDLFLTRHSRFQLRWNCFFNQKILNNVKVYCLLIRLKNPNEIAISSIERGEMSLDILMIEKNFTLAKLMKKGILIIEPVRLSVQNNGQLIIYRTIGISLVQKNKHKISKRYKKKIEKSITKYQKKTVNRKKNHYDFFVPENILSPKRRREFRILICFNLKKKNASDRNSRFDKNIQNLTTVLHKKKDLDKDQNNLIKFKSFLWPNFRLEDLACMNRYWFNTTNGNHFSMIRIHMYTRFPIH
What is the function of this protein?
Involved in protein precursor import into chloroplasts.  May be part of an intermediate translocation complex acting as a protein-conducting channel at the inner envelope.
What are the official names of this protein?
Protein TIC 214, Translocon at the inner envelope membrane of chloroplasts 214, AtTIC214.
What is the protein family that this protein belongs to?
Belongs to the TIC214 family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.