PharMolix/UniProtQA huggingface dataset:
Protein: DAPA_SYNP6
Sequence: MPQPYPFGRVITAMITPFNAEGQVAYDIAQSLAVHLVEQGSDGLVICGTTGESPTLTWEEELQLFRAVKEAVGDRAAVIAGTGSNCTREAIAATQSAATLGLNGSLQVVPYYNKPPQEGLYAHFRAIAEACPDLPLMLYNIPGRTGQSLQPETVARLASLPNVVAIKAASGNVEEVSALRQLLPDSFAIYSGDDSLTLPMLAVGAQGVVSVASHLVGPQLQALIQAFEAGNVARAQQLHHQLYPLFKALFLTTNPIPVRAAMELLGWSIGLPRLPLVPASAEIRQALASCLTELGLYTA
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RGI1_PICGU
Sequence: MTAKKSKSGRMTTALDLTTCEKLEHLQPIPKSRSSSITSIESEDGMMSTVLKPPPRRDFDDLMAFEGFIRDETWDNDFDYCHAHLTYYPPFIMKEVHNNLDKIKPTMNKNSRKFKRNLQHHIKKHLMHDMETCSGFKMDFNKVGMVETPTKVKWRFEDMGDHGFSKEEEDMYGRHWKLELEVTCNNENPLVEVDYKATPIM
What is the function of this protein?
Involved in the control of energetic metabolism and significantly contribute to cell fitness, especially under respiratory growth conditions.
What are the official names of this protein?
Respiratory growth induced protein 1.
What is the protein family that this protein belongs to?
Belongs to the RGI1 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ATPE_MYXXD
Sequence: MAKLTVEIVTPEKRILSVQADEAIVPGGRGLFGVRPGHTPFLSLMEPGALTLIESGRRESYFVAGGFVEVGNDKVLVLADAAEPVTGIDVEGARRRMAEAQERMKGMSSEDARFELEQATVRREAARIGAANTARA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: UVRC_STRPZ
Sequence: MNELIKHKLELLPDSPGCYLHKDKEGTIIYVGKAKNLKKRVRSYFRGSHDTKTELLVSEIVDFEYIVTESDTEALLLEINLIQKNMPKYNIKLKDDKSYPFLKITNESFPRLVITRYIKKNDGLYFGPYPDSYTANEVKKLLDRIFPFKKCKNPINKVCFYYHLGQCCAHTICHTDKAYWDRLIDDVKHFLNGKDDKIIEDLRSKMLAASEEMAFERAAEYRDLISGIATMRTKQRVMSKDLQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNLFPYYNDAEEDFLTYMGQFYQDKQHFIPKEVFIPEAIDEELVAAIVPTKIIKPKRGEKKQLVALATKNARVSLQQKFDLLEKDIKKTSGAIENLGQLLRIDKPVRIEAFDNSNIQGTSPVAAMVVFVDGKPSKKDYRKFKIKTVVGPDDYASMREVLFRRYSRVKKEGLQAPNLIIVDGGVGQVNVAKDVIEKQLGLTIPVAGLQKNDKHQTHDLLFGNPLEVVPLPRRSEEFFLLHRIQDEVHRFAVTFHRQVRRKNSFSSTLDHISGLGPKRKQLLLRHFKTITAIASATSEEIQALGIPKTVVEAIQQQITDNKNDRSSP
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_HELMI
Sequence: MGKAQANIRNFCIIAHIDHGKSTLADRILEFTGALTEREMEDQVLDSMDLERERGITIKLQAVRLQYKAKDGQVYTLNLIDTPGHVDFTYEVSRSLAACEGALLVVDAAQGIEAQTLANVYLALENDLEIIPVVNKIDLPSAEPDRVKQEIEDVIGLDASDAILVSAKAGIGIEETLEAIVAKIPPPEGDPTAPLQCMIFDSFYDAYKGAISYVRVVEGTVKKGTKIKMMSTGKTFEVTEVGVFTPAPRQVEKLSSGEVGFIVASIKNVKDTRVGDTITDADHPAKEPLPGYRQVTPMVYCGLYPVEGAGYEDLRDALDKLRLNDAALIYEPETSVALGFGFRCGFLGLLHMEIVQERLEREFDLDLITTAPNVIYKVNQTDGQVVFVDNPTKLPPNQKIETIEEPYVKASVMVPSDFVGAVMELCQEKRGVFINMDYIAAQRVMLIYELPLAEIIFDFFDQLKSRTKGYASLDYELIGYRVSELVKLDILLNGDLIDAFSIIVHRDRAYNRGRALADKLKDLIPRQMFEVPIQAVIGNKVIARETIKAIRKNVLAKCYGGDISRKRKLLEKQKEGKKRMKQVGSVEIPQEAFMAVLSIDK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: EX7L_BACMK
Sequence: MEKQYLTVTALTRYIKTKIEYDPHLQSVWLKGEISNFKYHSRGHMYFTLKDENARIAAVMFAGHNRNIKFRPENGMKVLVKGKISVYEASGSYQIYIQDMQPDGIGNLHLAYEQLKVRLEEEGLFSQVYKKIIPPYAKTIGVITSPTGAAIRDIITTIKRRYPIGNVIVFPVLVQGESAAPSIVQAIRTANEMGDIDVLIVGRGGGSIEELWAFNEEVVAREIFTSEIPIISAVGHETDFTIADFVADLRAPTPTAAAELAVPNTIELQEKVLQRTLRLQRAMRERVHKKEEKLQVLQKSYAFRYPRQVYEQKEEQLDRALEQLVLAKERYIDKKVNQLKQLSFYLEKHHPSQKIIQTKTAIETLQKQLQREMQTLLQTKEFVFVRAAQKLEVLSPLKVMMRGYGLVYDEEKQVLKSVKDVSLGDAVSVQLQDGILDCSVSSIEERELNNGK
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MALD_STRPN
Sequence: MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNVSAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYNFLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLMKGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSFLLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSGGDKG
What is the function of this protein?
Part of the binding-protein-dependent transport system for maltodextrin; probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Maltodextrin transport system permease protein MalD.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NH2L1_XENLA
Sequence: MTEPEVNPKAYPLADAQLTKTLLDLVQQSANYKQLRKGANEATKTLNRGIAEFIVMAADAEPLEIILHLPLLCEDKNVPYVFVRSKQALGRACGVSRPVIACSVTIKEGSQLKPQIQSVQQAIERLLV
What is the function of this protein?
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.  Involved in pre-mRNA splicing as component of the spliceosome.  Binds to the 5'-stem-loop of U4 snRNA and thereby contributes to spliceosome assembly.  The protein undergoes a conformational change upon RNA-binding.
What are the official names of this protein?
NHP2-like protein 1, High mobility group-like nuclear protein 2 homolog 1, U4/U6.U5 small nuclear ribonucleoprotein SNU13, U4/U6.U5 tri-snRNP 15.5 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus.
Protein: NDK_AFIC5
Sequence: MATERTFSIIKPDATARNLTGAVNAIIEKAGLRIIAQKRIRMTREQAETFYAVHKARPFFGELVDFMTSGPVVVQVLEGDNAISKYREVMGATDPSKAADGTIRKVHALSIGENSVHGSDAAETAAVEIAQFFAGNEIVG
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UFM1_BOVIN
Sequence: MSKVSFKITLTSDPRLPYKVLSVPESTPFTAVLKFAAEEFKVPAATSAIITNDGIGINPAQTAGNVFLKHGSELRIIPRDRVGHC
What is the function of this protein?
Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to lysine residues of substrate proteins as a monomer or a lysine-linked polymer.  The so-called ufmylation, requires the UFM1-activating E1 enzyme UBA5, the UFM1-conjugating E2 enzyme UFC1, and the UFM1-ligase E3 enzyme UFL1.  Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress.  Ufmylation of TRIP4 regulates nuclear receptors-mediated transcription.
What are the official names of this protein?
Ubiquitin-fold modifier 1.
What is the protein family that this protein belongs to?
Belongs to the UFM1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: RL1_BRUA2
Sequence: MAKISKRINKIREGVDRNKLYDLSAAIGLVKERAVAKFDETVEIAMNLGVDPRHADQMVRGVVNLPNGTGRTVRVAVFARGDKAEEAKKAGADIVGAEELFEIVNGGKIEFDRCIATPDMMPLVGRLGKVLGPRGMMPNPKVGTVTTDVAAAVAASKGGAVEFRVEKAGIIHAGIGKVSFDNAKLEENIKAFADAVIKAKPSAAKGEYVKRVSISSTMGVGVKVDPSTVKVVD
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: GREA_CLOBL
Sequence: MSEAKKYVMTYEGVKKLEEELEYLKTVKRKEITEKIKVALSFGDLSENSEYDEAKNEQAFVEGRIIQLENMLKNASIVDENEVPKDIVSVGSIVKVKDYEFDEEVEYIIVGSAEADPMNNKISNESPVGHGLIGKKVGDIIEVTVPDGVSKYEILEVNRA
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: ARAG_HALH5
Sequence: MNMPNCLLEMRNITKAFPGVKALNNVNLKVEQGEIHALVGENGAGKSTLMKVLSGVYPHGTYEGDILFEGRVCQFKDIKESEQLGIVIIHQELALVPELSIAENIFLGNEQAKNGVIDWNQTITEAAKLLKKVGLSDSPRTLAMNIGVGKQQLVEIAKALSKKVKLLILDEPTAALNEEDSQNLLHLLLEFKKQGMTSIIISHKLNEISYVADHLTILRDGQSIETLSLQSGEVTEDRIIKGMVGRDLENRFPPREPKIGDVILEVNHWHVDDPLHPDRSLIKDVNLYLKRGEIVGVAGLMGAGRTELAMSIFGKSYGKNIRGQLIKDGKEIKVHSVKDAIDHGLAYVTEDRKTYGLILIDDIKHNISLTSLEKLSKNGVVDKTREVKEAEDFRKKMNIRTPSIDQKTGNLSGGNQQKVVLSKWILSGPDILILDEPTRGIDVGAKYEIYSVIHELAAQGKAVLVISSELPELLGLSDRIYALCEGRITGEVTREEANQEILMKYMTRTGGNGHEVS
What is the function of this protein?
Part of the binding-protein-dependent transport system for L-arabinose.  Probably responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
L-arabinose transport ATP-binding protein AraG.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: YQHA_ECO81
Sequence: MERFLENAMYASRWLLAPVYFGLSLALVALALKFFQEIIHVLPNIFSMAESDLILVLLSLVDMTLVGGLLVMVMFSGYENFVSQLDISENKEKLNWLGKMDATSLKNKVAASIVAISSIHLLRVFMDAKNVPDNKLMWYVIIHLTFVLSAFVMGYLDRLTRHNH
What are the official names of this protein?
UPF0114 protein YqhA.
What is the protein family that this protein belongs to?
Belongs to the UPF0114 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS18_SYMTH
Sequence: MRRERGRRARRRVCSFCVDKIEHVDYKDAARLKRYITERGKILPRRISGNCARHQRQLTVAIKRARIMALLPFTVE
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: DRE22_TRYCC
Sequence: MSSKPTQAFSLKTRQAVDEDALLTEEDRVVKEATKGEDCTTRRRACKNCTCGRAELERKMLAEGKKVEMPQMPAGGCGNCAKGDAFRCATCPFLGQPAFDNTSDGKVKLNLTDDI
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.  Required for the maturation of extramitochondrial Fe-S proteins.  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex.  Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase.  Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit.
What are the official names of this protein?
Anamorsin homolog 2, Fe-S cluster assembly protein DRE2 homolog 2.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space.
Protein: RPSC_MYXXA
Sequence: MQASNSFSSPDSLSTYLSEINQYPLLTQPQEQELSKRFRAGDLAAGHQLVTANLRFVVKVAYEYRSYGLKMSDLIQEANIGLMKAVQKFDPDKGIRLISYAVWWIRAYIQNCILKNWSLVKLGTTQAQRRLFFSLARTRRELEKMGAGDANVVNAEEIARKLNVKASEVREMEQRMGGRDLSLDAPMGEDGDATHLDFVESESVSAVDEVADRQQANLTRELVQRALRRLDPRERFIIEQRVMGDAEMTLSELGEHFGFSRERARQLEIRAKDKLKLALVTLMAEAGVDESTLNA
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  This sigma factor is essential for normal fruiting body formation.
What are the official names of this protein?
RNA polymerase sigma-C factor.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family.
Protein: COX3_CARAU
Sequence: MAHQAHAYHMVDPSPWPLTGAIAALLMTSGLAIWFHFHSTTLMTLGLILLLLTMYQWWRDIIREGTFQGHHTPPVQKGLRYGMILFITSEVFFFLGFFWAFYHSSLAPTPELGGCWPPTGITPLDPFEVPLLNTAVLLASGVTVTWAHHSIMEGERKQAIQSLALTILLGFYFTALQAMEYYEAPFTIADGVYGSTFFVATGFHGLHVIIGSTFLAVCLLRQIQYHFTSEHHFGFEAAAWYWHFVDVVWLFLYVSIYWWGS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: VASP_BOVIN
Sequence: MSETVVCTSRATVMLYDDSNKRWLPAGTGPQAFSRVQIYHNPTANSFRVVGRKMQPDQQVVINCAIVRGVKYNQATPNFHQWRDARQVWGLNFGSKEDATQFANGMASALEALEGGGPLPPPPPTAPPTWSAQNGPSPEEMEQQKRQQQSELMERERRASNAGGPPAASAGAPPPPPGPPPPPGPPPPPGLSSSGVSAATQGAGGGPPPAPPLPTAQGPSGGGTGAPSLASAIAGAKLRKVSKQEEASAGPVAPKAESSRSTGGGLMEEMNAMLARRRKATQVGEKPAKDESANQEESDARVPAHSESVRRPWEKNSTTLPRMKSSSSVTTSEAHPATPSSSDESDLERVKQELLEEVRKELQKVKEEIIEAFVQELRKRGAP
What is the function of this protein?
Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration.  VASP promotes actin filament elongation.  It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein.  VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end of growing actin filaments.  Plays a role in actin-based mobility of Listeria monocytogenes in host cells.  Regulates actin dynamics in platelets and plays an important role in regulating platelet aggregation (By similarity).
What are the official names of this protein?
Vasodilator-stimulated phosphoprotein, VASP.
What is the protein family that this protein belongs to?
Belongs to the Ena/VASP family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Cell junction, tight junction. Cell projection, lamellipodium membrane. Cell projection, filopodium membrane. Note=Targeted to stress fibers and focal adhesions through interaction with a number of proteins including MRL family members. Localizes to the plasma membrane in protruding lamellipodia and filopodial tips. Stimulation by thrombin or PMA, also translocates VASP to focal adhesions. Localized along the sides of actin filaments throughout the peripheral cytoplasm under basal conditions. In pre-apoptotic cells, colocalizes with MEFV in large specks (pyroptosomes) (By similarity).
Protein: RS8E_METMA
Sequence: MRWQGSSRRKATGGKIIAARGKRKFEMGRESAETRISDVKRKNVHTMGGNRKVRLLQSNVANITNPKDGKTVTATIETVIDNTANKHYVRRNILTKGSVIRTPVGTARVTSRPGQDGVINAVLIE
What are the official names of this protein?
30S ribosomal protein S8e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS8 family.
Protein: ASIL2_ARATH
Sequence: MEDDEDIRSQGSDSPDPSSSPPAGRITVTVASAGPPSYSLTPPGNSSQKDPDALALALLPIQASGGGNNSSGRPTGGGGREDCWSEAATAVLIDAWGERYLELSRGNLKQKHWKEVAEIVSSREDYGKIPKTDIQCKNRIDTVKKKYKQEKVRIANGGGRSRWVFFDKLDRLIGSTAKIPTATSGVSGPVGGLHKIPMGIPMGSRSNLYHQQAKAATPPFNNLDRLIGATARVSAASFGGSGGGGGGGSVNVPMGIPMSSRSAPFGQQGRTLPQQGRTLPQQQQQGMMVKRCSESKRWRFRKRNASDSDSESEAAMSDDSGDSLPPPPLSKRMKTEEKKKQDGDGVGNKWRELTRAIMRFGEAYEQTENAKLQQVVEMEKERMKFLKELELQRMQFFVKTQLEISQLKQQHGRRMGNTSNDHHHSRKNNINAIVNNNNDLGNN
What is the function of this protein?
Transcription regulator that may repress the maturation program during early embryogenesis.
What are the official names of this protein?
Trihelix transcription factor ASIL2, 6B-interacting protein 1-like 2, Trihelix DNA-binding protein ASIL2.
What are the subcellular locations of this protein?
Nucleus.
Protein: DNLJ_BORPA
Sequence: MAQAGPTPQQAIARLRAEIEQHNIRYYVHDDPSVPDAEYDALMRDLQALEAEHPELVTPDSPTQRVGAAPLAEFGSVRHAVPMLSLGNAFDEEDVRAFDKRVADTLRGAGLLGLDQQVEYFCELKLDGLAISLCYEEGRLAQAATRGDGQTGEDVTANIRTIKGVPLRLHGAPRVLEVRGEVLMNRAEFERLNRTQAARGEKVFVNPRNAAAGSLRQLDPRITAQRPLRFFAYSWGEVHGLPEGMPTRFDEPAPGVRVASTLPRDTHGGMLDWLAELGLPVNLRHNHRERGADGLLAFYERIGKLRADLPYDIDGVVYKVDALPSQRVLGFVARAPRFALAHKFPAEEAVTQLLGIEVQVGRTGAITPVARLAPVFVGGVTVTNATLHNEDEIRRKDVRIGDTVIVRRAGDVIPEVVGPVLEKRPADAREFVMLTACPICGSAIERPEGEAIARCTGGLFCAAQRKQTLLHAAGRKALDIEGLGEKLIDQLVDADRVKSLADIYSLTAFELAALERMGKKSAENLVAAIDQARRPALGRLLFALGIRHVGETTARDVARHFGSMERIMDASEEALLAVPDVGGVVAGSIRRFFAEPHNREIVEQLTQQGVHPQAEAEPEGTSLAGKTFVLTGTMPNWTRDEATRRILAAGGKVSGSVSKKTAYLVTGEDAGSKLTKAQELGVPVLDEDGLKALLGL
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: IUNH_LEIMA
Sequence: MPRKIILDCDPGIDDAVAIFLAHGNPEIELLAITTVVGNQSLEKVTQNARLVADVAGIVGVPVAAGCTKPLVRGVRNASHIHGETGMGNVSYPPEFKTKLDGRHAVQLIIDLIMSHEPKTITLVPTGGLTNIAMAVRLEPRIVDRVKEVVLMGGGYHTGNASPVAEFNVFIDPEAAHIVFNESWNVTMVGLDLTHQALATPAVQKRVREVGTKPAAFMLQILDFYTKVYEKEHDTYGKVHDPCAVAYVIDPTVMTTERVPVDIELNGALTTGMTVVDFRYPRPKNCRTQVAVKLDFDKFWCLVIDALERIGDPQ
What is the function of this protein?
Catalyzes the hydrolysis of the N-glycosidic bond of all of the commonly occurring purine and pyrimidine nucleosides into ribose and the associated base, but has a preference for inosine and uridine as substrates.  Likely functions in purine salvage from the host, a fundamental pathway since protozoan parasites such as L. major are incapable of de novo purine biosynthesis.
What are the official names of this protein?
Inosine-uridine preferring nucleoside hydrolase, IU-NH, IU-nucleoside hydrolase, Non-specific nucleoside hydrolase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family.
Protein: PDXA_METCA
Sequence: MPPRLLLTSGEPAGIGPDLCVLLSRRPFPCGITVLGDPDLLESRARLLGVPIELRRVVSGDVVPPHEPGVLHVLPTRRQPGTAPGKLDPANAAYVLETIADGARACLAGHYDALVTAPVQKSVINEAGIAFTGHTEFIAGITGGSPVMMLAAEGFRVALATTHLPLAEVSRAITVERLTGVLGVLHEDLVRRFGFSRPRILVCGLNPHAGEGGHLGGEEITVIEPVLARLRQDGMDLTGPLPADTLFLPHNLDRADAVLAMYHDQGLPVLKYAGFSRAVNITLGLPIIRTSVDHGTALDRAGTGQIDTGSLEEAVRVAMEMATGRPAESP
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METXA_MYCSK
Sequence: MKSPAVPALDLPAEGETGVVDIGPLTLESGAVIDDVSIAVQRWGELSPNRDNVVMVLHALTGDSHVTGPAGPDHPTPGWWDGVAGPGAPIDTDRWCAVSTNVLGGCRGSTGPSSIAPDGRPYGSRFPAVTIRDQVTADLAALEALGITEVAAVVGGSMGGARALEWIVGHPATVRSALILAVGARATADQIGTQSTQVAAIKADPDWCGGDYHDTGRVPSTGLAIARRFAHLTYRGEVELDDRFGNHAQGDESPTDGGRYAVQSYLEYQGAKLVERFDAGTYVTLTDALSSHDVGRGRGGVRAALQGCRVPTIVGGVTSDRLYPLRLQQELAELLPGCTGLDVVDSVYGHDGFLVETEAVGKLIRRTLELAER
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_CUPTR
Sequence: MSRIQKTFAALAAQQKKGLIPFITAGDPEPGLTVALMHALVAGGADVIELGVPFSDPMADGPVIQRASERALAQGVSLTQVLQWVREFRQTNTDTPVVLMGYANPIERMGEAAFAAAASAAGVDGVLVVDYPPEECESFAGLMRDHGMDPIFLLAPTSTDARIEAVAKVASGYLYYVSLKGVTGSASIDLDSVAARLPLIKQHANLPVGVGFGIRDAQTARAIGSVADAVVIGSRLVQLLEDTPREQAVTALQSFIAEIRQALDA
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.