PharMolix/UniProtQA huggingface dataset:
Protein: GREA_MYCBO
Sequence: MTDTQVTWLTQESHDRLKAELDQLIANRPVIAAEINDRREEGDLRENGGYHAAREEQGQQEARIRQLQDLLSNAKVGEAPKQSGVALPGSVVKVYYNGDKSDSETFLIATRQEGVSDGKLEVYSPNSPLGGALIDAKVGETRSYTVPNGSTVSVTLVSAEPYHS
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: CP343_HUMAN
Sequence: MDLIPNFAMETWVLVATSLVLLYIYGTHSHKLFKKLGIPGPTPLPFLGTILFYLRGLWNFDRECNEKYGEMWGLYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVNLDSLNNPQDPFLKNMKKLLKLDFLDPFLLLISLFPFLTPVFEALNIGLFPKDVTHFLKNSIERMKESRLKDKQKHRVDFFQQMIDSQNSKETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKPCKETQIPLKLDNLPILQPEKPIVLKVHLRDGITSGP
What is the function of this protein?
Exhibits low testosterone 6-beta-hydroxylase activity.
What are the official names of this protein?
Cytochrome P450 3A43.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: LPPO_MYCTO
Sequence: MTDPRHTVRIAVGATALGVSALGATLPACSAHSGPGSPPSAPSAPAAATVMVEGHTHTISGVVECRTSPAVRTATPSESGTQTTRVNAHDDSASVTLSLSDSTPPDVNGFGISLKIGSVDYQMPYQPVQSPTQVEATRQGKSYTLTGTGHAVIPGQTGMRELPFGVHVTCP
What are the official names of this protein?
Putative lipoprotein LppO.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: RECF_CLOK5
Sequence: MYIKYLKLINFRNYKELDIEFDKNINIFVGDNAQGKTNILESMYYCSIGKSPRTSKDKELINWDNKESYIKVHILKKLFNKKIEIKIFKEGKKGININSIKVSKLSELMGVLNVVMFSPEDLKIIKESPVYRRKFLDIELCKFSKKYYYGLVQYNKVLTARNIILKKWNKGNYIDILQVYDKQLAKYGEVIIKLRNNYLKKLSEKGKVIHSDITSGIENIEFKYMTCLTNFDNIEDDLFKILEFNRKKDIYKGITLYGPHRDDFIVNINGVNVRNFGSQGQQRTSILTMKFASLEIIKEIIGEYPVLLLDDVLSELDKNRQKYILSSIKDIQTFITCTGIDDIKKSIIDEAQLFIVKKGKVSRI
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNFT2_HUMAN
Sequence: MWLFTVNQVLRKMQRRHSSNTDNIPPERNRSQALSSEASVDEGGVFESLKAEAASPPALFSGLSGSLPTSSFPSSLVLGSSAGGGDVFIQMPASREEGGGRGEGGAYHHRQPHHHFHHGGHRGGSLLQHVGGDHRGHSEEGGDEQPGTPAPALSELKAVICWLQKGLPFILILLAKLCFQHKLGIAVCIGMASTFAYANSTLREQVSLKEKRSVLVILWILAFLAGNTLYVLYTFSSQQLYNSLIFLKPNLEMLDFFDLLWIVGIADFVLKYITIALKCLIVALPKIILAVKSKGKFYLVIEELSQLFRSLVPIQLWYKYIMGDDSSNSYFLGGVLIVLYSLCKSFDICGRVGGVRKALKLLCTSQNYGVRATGQQCTEAGDICAICQAEFREPLILLCQHVFCEECLCLWLDRERTCPLCRSVAVDTLRCWKDGATSAHFQVY
What are the official names of this protein?
RING finger and transmembrane domain-containing protein 2, Transmembrane protein 118.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PSBA_PROMA
Sequence: MTTIRQQRSSLLKGWPQFCEWVTSTDNRIYVGWFGVLMIPCLLAAAICFVVAFIAAPPVDIDGIREPVAGSFLYGNNIISGAVVPSSNAIGLHFYPIWEAATLDEWLYNGGPYQLVIFHFLIGICGWMGRQWELSYRLGMRPWICVAYSAPVSAAFAVFLVYPFGQGSFSDGMPLGISGTFNFMFVFQAEHNILMHPFHMAGVAGMFGGSLFSAMHGSLVTSSLIRETTETESQNYGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAIFPVVCVWLTSMGICTMAFNLNGFNFNQSVVDANGKVVPTWGDVLNRANLGMEVMHERNAHNFPLDLAAAESTSVALVAPSIG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: HAD1_CRYNH
Sequence: MSVFTKSAFTMSALPSPNTSQPPSAAPSRRGSFANGLASGQLTPVTDPHIVSINVESVLFDMDGTLINSSPAVVKAWELFAEKYPLDLDDILRSAHGMRTIDVLKKWCKITDPELLASEVIRFETAILNSAEDIAKHSGKAGIEVLPGVAKLLADLGEEADKRDGEEKWAICTSSTYFYAGKAIPIAGLPTPKVFVTADSVTRGKPFPDPYLLGASGCNASPFESLVVEDAPTGIRSGKASGALVLATCTSHEREELERERPDFLVDDLSHVKASWDAATNTFNLIIEQPIDRYTPRPTPDVTPVITPAMSRSNSFSGVGQDRPSVRNTQTIMKGSDDLTGNDSVVGSPAASRPGSPGADDSVEKRAEMEFHRRASQSGQAGVTLDAFRRALAGNAAKRRAQSQGEMSQDE
What is the function of this protein?
Probable phosphatase (Probable).  Required for cell wall integrity and virulence (PubMed:29233914).
What are the official names of this protein?
Probable phosphatase HAD1.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily.
Protein: MURQ_STRAW
Sequence: MTSMSHHRSLQAELETLTTEAFRPELAEIDQLPTLEIARLMNGEDATVPAAVAARLPQIAAAIDAVADRMARGGRLVYAGAGTAGRLGVLDASECPPTFNTDPSEVVGLIAGGPSAMVTSIEGAEDSKELAAGDLAGLGLTADDTVVGVSASGRTPYAIGAVEYARARGALTVGLSCNADSALAAAADHGIEIVAGPELLTGSTRLKAGTAQKLVLNMLSTITMIRLGKTYGNLMVDVRASNEKLRARSRRIVALATGAADEEVERALAATDGEVKNAILTILGGVDGPTAARLLEESDGHLRAALAAAPR
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: C7BL2_TANPA
Sequence: MEPFTIFSLVVASLVFFACWALVAPNTSKNLPPGPPKLPIIGNIHQLKSPTPHRVLKDLAKKYGPIMHLQLGQVSTVVVSTPRLAQEIMKTNDISFADRPTTTTSQIFFYKAQDIGWAPYGEYWRQMKKICTLELLSAKKVRSFSSIREEELTRIRKILEFKAGTPINYTEMTIEMVNNVICKATLGDCCKDQALLIELLYDVLKTLSAFNLASYYPRLQFLNVISGKKAKWLKMQKRLDDIMEDILKEHRAKGRAKNSDQEDLVDVLLRIKDTGGLDINVTDEHVKAVVLDMLTAGTDTSSTTLEWAMTELMRNPDMMKRAQEEVRSVVKGEHVTETDLQSLHYLKLIVKETMRLHAPTPLLVPRECRQDCNVDGYDIPAKTKVLVNAWACGVDPGSWENPDSFIPERFENSSINFMGADFQYIPFGAGRRICPGLTFGLSMVEYPLAHFLYHFDWKLPYGMKPHELDITEITTISTSLKHHLKIVPFPKSSLAK
What is the function of this protein?
Involved in the biosynthesis of germacrene-derived sesquiterpene lactones (PubMed:30468448).  Component of the parthenolide biosynthetic pathway; parthenolide and conjugates are promising anti-cancer drugs highly active against colon cancer cells (PubMed:30468448).  Hydroxylates germacrene A acid to 6-alpha-hydroxy-germacrene A acid, a precursor of sesquiterpene lactones that spontaneously undergoes a lactonization which yields costunolide (PubMed:24704560).
What are the official names of this protein?
Costunolide synthase, TpCOS, Cytochrome P450 71BL2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: CYB_RANAM
Sequence: MTPTMRKFHPLLKFINYSFIDLPTPSNISASWNFGSLLGLCLIAQIATGLFLAMHYTADTSLAFSSIAHICRDVNNGWLLRNLHANGASFFFICIYFHIGRGLYYGSYLYKETWNIGVILLFLLMATAFVGYVLPWGQMSFWGATVITNLLSAAPYIGSNLVQWIWGGFSVDNATLTRFFTFHFILPFIITAVSLIHLLFLHQTGSSNPTGLNSNLDKVSFHPYFSYKDLLGFVIMLGALASLSTFAPNLLGDPDNFTPANPLVTPPHIKPEWYLLFAYAILRSIPNKLGGVLAVVLSIMVLFLMPIIHTSKLRSLMFRPIAKTFFWALIANTAILTWIGGQPVEDPFITIGQIASGLYFLIFVLLIPSLGLLENKLLKI
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GPR85_MOUSE
Sequence: MANYSHAADNILQNLSPLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPFVFNSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCTFQHRSFRANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAAANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGPYLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCRKSRLPREPYCVI
What is the function of this protein?
Orphan receptor.
What are the official names of this protein?
Probable G-protein coupled receptor 85, Super conserved receptor expressed in brain 2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum.
Protein: PANE_LACLA
Sequence: MRITIAGAGAMGSRFGLMLHKGGNEVTLIDGWPEHVKAIKEHGLRANYNGEELTAHLSVELQSEISSKEKTDLIILFTKAMQLDKMLQDIKPLIDEHTKVLCLLNGIGHEDTIEKYVSKNNIFIGNTMWTAGLEGPGKAKLFGDGSVELQNLISGEEETAKKLAEILSESGLNAKYSNNIHYSIYRKACVNGTMNGLCTILDTNMAGLGETKPAHDMVVTIVNEFAAVAKFENVNLDIAEVVQHVETCFDPSTIGLHYPSMYQDLIKNNRLTEIDYINGAVSRKGKKYNVATPYCDFLTQLVHSKEELLKAK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
What are the official names of this protein?
2-dehydropantoate 2-reductase, Ketopantoate reductase, KPR.
What is the protein family that this protein belongs to?
Belongs to the ketopantoate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOHJ_ECO57
Sequence: MSKTLNIIWQYLRAFVLIYACLYAGIFIASLLPVTIPGSIIGMLILFVLLALQILPAKWVNPGCYVLIRYMALLFVPIGVGVMQYFDLLRAQFGPVVVSCAISTLVVFLVVSWSSQLVHGERKVVGQKGSEE
What are the official names of this protein?
UPF0299 membrane protein YohJ.
What is the protein family that this protein belongs to?
Belongs to the UPF0299 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: STEL8_DROME
Sequence: MSSSQNNNSSWIDWFLGIKGNQFLCRVPTDYVQDTFNQMGLEYFSEILDVILKPVIDSSSGLLYGDEKKWYGMIHARYIRSERGLIAMHRKYMRGDFGSCPNISCDRQNTLPVGVSAVWGKSTVKIHCPRCKSNFHPKSDTQLDGAMFGPSFPDIFFSMLPNLTSPLDDPRT
What is the function of this protein?
Unknown.  In males lacking the Y chromosome, its strong overexpression leads to the appearance of proteinaceous star-shaped crystals in the primary spermatocytes causing meiotic drive, possibly by interfering with normal casein kinase 2 activity.
What are the official names of this protein?
Stellate orphon protein at 12D.
What is the protein family that this protein belongs to?
Belongs to the casein kinase 2 subunit beta family.
Protein: GATB_GLOVI
Sequence: MTSTAPPKVQYEAVIGLEVHVQLSTETKLFCRCSTRFGNTPNTNICPICTGQPGTLPVLNQQALDYAVLTASALNCQIHPQGLSKFDRKQYFYPDLPKNYQISQYDLPLAERGWLEIEVEGEPAKRIGITRLHMEEDAGKLVHAGADRLSGSTHSLVDFNRAGVALCEIVSEPDIRTAAEAAAYAGELRRIVRYLGVCDGNMQEGSLRFDLNISVRPAGEGKFGTKVEIKNLNSFNSLQRAVEYEFARQVDCLLSGERIVQETRLWDEATQRTISMRSKEEANDYRYFPEPDLVPIALNGTQIDAYRQRLGELPAQKRHRYRETLGLSSYDAGVLTDEREVAEYFEQVVALGIPAKQAANFVSGAVAAHLNETRRSISQIKVTPEVSAELLALINQGIISNRIANELLPDLFEKGGSPRALVEERGLTQISDRGQLEQIVDEVLAGESDSVAAYRGGRTKLLGFFVGKVMKKTAGRADPQVVNDLLQSKLAEQPTAPPPEPESAAETPEAPPAVEDAPPEAPTEAITAEAGSAEAITAASEEPDTPVSHQDAHA
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: FENR_STRPI
Sequence: MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPAILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTSKGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSAVDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLAKLEITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYAIGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: RL18_ACIAC
Sequence: MLTKKEQRLRRSRQTRIRIAQQGVVRLTVNRTNLHIYASVISEDGSRVLASASTAEAEVRKELGGSGKGGNAAAAQMIGKRIAEKAKAAGIEKVAFDRAGFAYHGRVKALAEAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: SYK_BURA4
Sequence: MTEPTQTQPAVAADENQIIAERREKLRALREQGVAYPNDFRPTHHAADLQATFADSDKAALEANPVEVSVAGRMMLKRVMGKASFATVQDGSGQIQFFVTPNDVGAETYDAFKKWDLGDIVAARGVLFRTNKGELSVQCKELRLLSKALRPLPDKFHGLADQEMRYRQRYVDLIVTPETRDTFRARTRTIASIRKFMDNADFMEVETPMLHPIPGGAAAKPFVTHHNALDMQMFLRIAPELYLKRLIVGGFERVFEINRNFRNEGVSPRHNPEFTMMEFYAAYTDYRWLMDFTEQLIRQAAIDALGTATIQYQGRELDLAKPFHRLTITQAIQKYAPQYTDGQLSDDAFLRTELKRFGVDVSQPAFLNAGIGALQLALFEETAESQLWEPTYIIDYPVEVSPLARASDTTPGITERFELFMTGREIANGFSELNDPEDQAARFKKQVEQKDAGDEEAMFFDADYIRALEHGMPPTGGCGIGIDRLVMLLTDSPTIRDVLLFPHLRRED
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNC_MYCTU
Sequence: MIRSRQPLLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVLGLTITDALFHRHPDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVLLGRGEANTGGADKSSILADGMESLLGAIYLQHGMEKAREVILRLFGPLLDAAPTLGAGLDWKTSLQELTAARGLGAPSYLVTSTGPDHDKEFTAVVVVMDSEYGSGVGRSKKEAEQKAAAAAWKALEVLDNAMPGKTSA
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism (By similarity).
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIR2_MACFA
Sequence: MLSVRIPLAPITNPQQLQLSPLKGLSLVDKENTPPALSGARVLASKTARRIFQEPAEPKTKAAAPGVEDEPLLRENPRRFVIFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWESLKPEERYFISHVLAFFAASDGIVNENLVERFSQEVQITEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREFLFNAIETMPCVEKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPSEERVREIIINAVRVEQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFSKVFRVENPFDFMENISLEGKTNFFEKRVGEYQRMGVMSSPTENSFTLDADF
What is the function of this protein?
Provides the precursors necessary for DNA synthesis.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).  Inhibits Wnt signaling (By similarity).
What are the official names of this protein?
Ribonucleoside-diphosphate reductase subunit M2, Ribonucleotide reductase small chain, Ribonucleotide reductase small subunit.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localized to the cytoplasm in S phase cells. May localize to the nucleus in G2 phase cells.
Protein: RNFA_ACTPJ
Sequence: MVDYILLIISTALINNFVLVKFLGLCPFMGVSKKVETAIGMGMATTFVLTVASLSAYLVETYVLIPLEAQFLRTLVFILVIAVIVQLTEMIVHKTSPTLYRLLGIYLPLITTNCAVLGVALLNVNLSNNLVESVLYGFGAALGFSLVLVLFAALRERLAAADVPRPFQGASIALITAGLMSLAFMGFTGLVKI
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit A, Rnf electron transport complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NORA_STAAW
Sequence: MNKQIFVLYFNIFLIFLGIGLVIPVLPVYLKDLGLTGSDLGLLVAAFALSQMIISPFGGTLADKLGKKLIICIGLILFSVSEFMFAVGHNFSVLMLSRVIGGMSAGMVMPGVTGLIADISPSHQKAKNFGYMSAIINSGFILGPGIGGFMAEVSHRMPFYFAGALGILAFIMSIVLIHDPKKSTTSGFQKLEPQLLTKINWKVFITPVILTLVLSFGLSAFETLYSLYTADKVNYSPKDISIAITGGGIFGALFQIYFFDKFMKYFSELTFIAWSLLYSVVVLILLVFANGYWSIMLISFVVFIGFDMIRPAITNYFSNIAGERQGFAGGLNSTFTSMGNFIGPLIAGALFDVHIEAPIYMAIGVSLAGVVIVLIEKQHRAKLKEQNM
What is the function of this protein?
Involved in quinolone resistance.  May constitute a membrane-associated active efflux pump of hydrophilic quinolones (By similarity).
What are the official names of this protein?
Quinolone resistance protein NorA.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PI16_BOVIN
Sequence: MHGSGSLLACLLPPLLLLGAAPGPAGALSEEEKHVMVELHNLYRTQVSPPATNMLQMRWDEELAAFAKAYAQQCVWGHNKERGRRGENLFAITGEGLDVPLAMEEWHHEREHYNLSAISCAAGQMCGHYTQVVWAKTERIGCGSHFCEKLQGVEETNIHLLVCNYEPPGNVKGQRPYQEGTPCSQCPLGYHCKNSLCEPIRGPEEAQDLSSLVPEAPSSLATEASSSRREGIDSSLATEPPPFLVTEVSGSLATKVLSSVETKAPSSLVTEDSPSMATKTPLSLATKVPSVLATHSLLSLDKRPATLLPKSTHDPIPKSADKEASSTRMPSRIPESSLHPKISLMGTREPLPLSQEEGEAEAELAHCSEILASVFPAQEKPGELQTTLKHKGHSSSKSLSNSPSASATANAVGGRTLALQSSLPDAEGPGKHGFRSGSNASPGHVGGLLLGLLLLLPLVLAGIF
What is the function of this protein?
May inhibit cardiomyocyte growth.
What are the official names of this protein?
Peptidase inhibitor 16, PI-16.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Secreted.
Protein: HTPX_GEOUR
Sequence: MNRLKTTLLLTCLTLLMVAMGSAIGGRSGMVFAFFMACAMNVFSYWFSDKIVLRMYGAQEITEAENPAFYGMVRRLAVQAGLPMPRVYVIPSESPNAFATGRNPDHAAVAATQGILRILTPEELEGVMAHELSHVKNRDILISTIAATIAGAISMLGNMLQWAAIFGGGRDNDEEGGGMLGGLAMAIIAPIAAMLIQMAVSRSREYLADESGARICGNPLSLANALRKLDSASRMLPMEEARPATAHLFIVNPLTGGALLKLFSTHPPMEERIAKLEAMAYRPLR
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FLGH2_BURTA
Sequence: MRILLALTWLAWLGACTSIEQPRPDFADDDLPPIATAPAAGRSGGVFNAVTAWSLASDGRAYRPGDTLTVTLEETTQASKRADTKFGKNGDMAVKPGVLFGSTVPFDSSFGAKRNFDGGGSSSQQNTLRGEITVIVNQVLAGGLLQVKGEKVLSLNQGEEVMRLSGYVRQADIDTNNRVSSRRIANARIKYVGKGALSDSNSAGWLTRFFNSPWMPF
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein 2, Basal body L-ring protein 2.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: ERFE_HUMAN
Sequence: MAPARRPAGARLLLVYAGLLAAAAAGLGSPEPGAPSRSRARREPPPGNELPRGPGESRAGPAARPPEPTAERAHSVDPRDAWMLFVRQSDKGVNGKKRSRGKAKKLKFGLPGPPGPPGPQGPPGPIIPPEALLKEFQLLLKGAVRQRERAEPEPCTCGPAGPVAASLAPVSATAGEDDDDVVGDVLALLAAPLAPGPRAPRVEAAFLCRLRRDALVERRALHELGVYYLPDAEGAFRRGPGLNLTSGQYRAPVAGFYALAATLHVALGEPPRRGPPRPRDHLRLLICIQSRCQRNASLEAIMGLESSSELFTISVNGVLYLQMGQWTSVFLDNASGCSLTVRSGSHFSAVLLGV
What is the function of this protein?
Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage: produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increased iron absorption and mobilization from stores.  Promotes lipid uptake into adipocytes and hepatocytes via transcriptional up-regulation of genes involved in fatty acid uptake.
What are the official names of this protein?
Erythroferrone, Complement C1q tumor necrosis factor-related protein 15, Myonectin.
What is the protein family that this protein belongs to?
Belongs to the adipolin/erythroferrone family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRPB2_AERPE
Sequence: MDLARYRFDLSIEEVPTSWYNILPDLPEEVPPPLNPKTGEPVDPSALAKLFPKALIEQEVSRERYIEIPGEVHEAYISFARRPTPLLRAVNLERALNTPAEIYYKYEGVTPTGSHKINTALAQAYYNKLEGVERLVTETGAGQWGSALSAAGAYFGVKVRVYMVRVSYLQKPYRRTLMELYGAEVYPSPSDKTEFGRKLLAENPNHPGSLGIAISEAIEDVINSGGNAKYSLGSVLNHVLLHQTVIGLEAEKQFREAGVYPDIMIGAVGGGSNFAGFTYPFIRHRLKGSSSTRFIAVEPKASPSMTRGVYTYDYGDTAGLTPLLKMHTLGHTYQVPPIHAGGLRYHGVAPTLSVLLKHGIVEARAYHQREVFRAAHMFAKAEGIVPAPESAHAVKAAIDEAIKARDEGRRVVIAFNLSGHGLLDLQGYREYLDGTLEDYEPEEIPASRR
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain 2.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: RS11_SALNS
Sequence: MAKAPVRARKRVRKQVSDGVAHIHASFNNTIVTITDRQGNALGWATAGGSGFRGSRKSTPFAAQVAAERCADAVKEYGIKNLEVMVKGPGPGRESTIRALNAAGFRITNITDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: INSM1_XENLA
Sequence: MPKGFLVKRNRKSPPVSYRVREDEENRGESLPGWMLLATMCPTGGAPPPSSPERLASAAPSCNNPRPPPAGQFGNPEAVPQTLYSPTRPVSREQRERKYLGSPVSAESFPGLGSSSEALLFPPTSTANGHHGLALLPPVSSSSSISRTHGKRPAPEPDVKAGAAPGTACKPPAAKKTKAIRKLTFEDEVTTSPVLGLKIKEGPVEPPRPRAPSSGPRPLGEFICQLCKEEYSDPFSLAQHKCSRIVRVEYRCPECHKVFSCPANLASHRRWHKPRPPAVPAVQPKEEALSDRDTPSPESGSEDGLYECPRCARKFRRQAYLRKHLLSHQVTKEPEEAGHMMYQSDEQRPQAKSPPSLNVPQECHPCPVCGETFPGKSSQERHIRLLHSSQLYPCKYCPATFYSSPGLTRHINKCHPSENRQVILLQVPVRPAC
What is the function of this protein?
May act as a transcriptional regulator (By similarity).  Plays a role in noradrenergic neuron, pancreatic and gastrointestinal endocrine cells differentiation during embryonic development.
What are the official names of this protein?
Insulinoma-associated protein 1, Zinc finger protein IA-1.
What is the protein family that this protein belongs to?
Belongs to the INSM1 family.
What are the subcellular locations of this protein?
Nucleus.