PharMolix/UniProtQA huggingface dataset:
Protein: FIBA_RABIT
Sequence: VDPGESTFIDEGATGR
What is the function of this protein?
Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix.  Fibrin has a major function in hemostasis as one of the primary components of blood clots.  In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization.  Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood.  However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo.  Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway.  Maternal fibrinogen is essential for successful pregnancy.  Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage.  May also facilitate the immune response via both innate and T-cell mediated pathways.
What are the official names of this protein?
Fibrinogen alpha chain.
What are the subcellular locations of this protein?
Secreted.
Protein: RL10_PROM4
Sequence: MGRTLESKKQIVEELKALLDQAEMALVIDYQGLTIKEMSDLRTRLGPSSGICKVTKNTLMRKAIDGDTSWSSLESLLNGTNAFVLVKGDVGGALKAVQAFQKETKKSKTKGGLFEGKLLSQDEIKAIANLPTKEVLMAQIAGALNSIATKMAVGINEVPSGLARSLKQHADSGEN
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: CSPL6_PICSI
Sequence: MAQGKESVSVVEMEGSGNGPAVEMRHFETLFRLLPVGLCISALVLMLKSEQSDQYMQLDYSNVDAFRCLAYANGICAGYSLISAFDSMVPVSHHISRSWILFLLDQGITYLMLAGGAVATQVLYVAYKGDEKATWEQICGSYGRFCNRAGASVIISFFALVCFLLLSLLSAYRLFSKYDPPIHGGAKLEDQTTAQI
What are the official names of this protein?
CASP-like protein 2A2, PsCASPL2A2.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y3092_BRUAB
Sequence: MRLRNFYSALALSAAVFAGPLYAAAPAMAAGTISGGFDVGPGGFQGNFNPLAATGGFTWLVTYFEPLVIYDDKLENIVGDLAKSFEISPDQLTYTFKLAHAKWHDGEPFTSKDAKFTFDLARNGKTGSVFAARLASIASVETPDEKTVVIKLKEPSPSMLDTLTKVMMLPEHALASIPPEQLAKNAWWSSTPIGTGPFKFNKYVADQYVELTANPDYRGGRPQVDKLINRYFADPAAAIAALRSGEIQFTYVDSNDVSTFSSDSAFRVIEGDSFVVNYVGFNQEVPLWKDLKVRQAFMHAINRDAIIQSLYGGAAKPANCVYVADRLVPKAIDAYAYDPQKARQLLDEAGWDKINGSKPITILTYYNSPLVANVLAAMQAMLAQVGINIVPRTVDTPTYNSIVYKQGGTADEFPLIFAGLQNGPDPSSINIGLNEKQIPPAGSNIMRIRMPAVTKALDAALAETNPAKRDARYQDVCKATNANLPWGTMWVANRYGVASSKLENFIWTPAPAGGPYQAHPEKWAILE
What is the function of this protein?
Probably part of an ABC transporter complex that could be involved in peptide import.
What are the official names of this protein?
Putative ABC transporter peptide-binding protein BruAb2_0792.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 5 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: ISPDF_NOVAD
Sequence: MNSVPSLPGQSVAAVVVAGGKGLRTGGPVPKQFVIWRGKPLLRHCVEALEAAGIAPIVVAIPAGWDEAATQALAGISMVRLVHGGATRQESVKAALEVLEGDAPARVLIHDAARPDLPGSVIERLLTALDKRTGAIPVLPVVDSMVRGSGDAMGETVAREDLYRVQTPQAFHYPAILAAHRAWQGEALAGDDAQVAMRAAHEIALVEGDEALRKVTFASDLEEQSMSVIPRTGMGFDVHRLVEGEELWLCGVNIPHGKGLSGHSDADVAIHALVDALLGAIAAGDIGDHFPPSDPQWKGASSDRFLAHAGTLVTEAGYRIANVDVTIICEAPKIGPHKAAMRETLARILGIDSALVSVKATTTERLGLTGRGEGIAAQAVATVVSG
What is the function of this protein?
Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
What are the official names of this protein?
Bifunctional enzyme IspD/IspF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the IspF family.
Protein: UPPS_LACPL
Sequence: MFAFFNKNDPADNTDVQLDPERIPAHVAIIMDGNGRWAKARHLPRVAGHKEGMNTVKKITIAASDLGVKVLTLYAFSTENWKRPTDEVNYLMQLPVSFFDTFVPDLIKNNVRVQVMGYVDHLPEATQKAVQNAIADTKDCDGMVLNFALNYGSRAEIVTGVQKIAQQVQDGQLAVGDIDDATIDAALMTAPLAPYNDPDLLIRTSGEERISNFLMWQIAYSELVFTDVKWPDFTAATLQACIADFQSRDRRFGGLSDHK
What is the function of this protein?
Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP).  UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
What are the official names of this protein?
Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific), Ditrans,polycis-undecaprenylcistransferase, Undecaprenyl diphosphate synthase, UDS, Undecaprenyl pyrophosphate synthase, UPP synthase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: YEIW_ECOL6
Sequence: MECRPGCGACCTAPSISSPIPGMPDGKPANTPCIQLDEQQRCKIFTSPLRPKVCAGLQASAEMCGNSRQQAMTWLIDLEMLTAP
What are the official names of this protein?
UPF0153 protein YeiW.
What is the protein family that this protein belongs to?
Belongs to the UPF0153 family.
Protein: Y1669_MYCLE
Sequence: MMPSTPRTSIPSITLNDENTMPLLGLGVAELSEDETERAVLAALEIGCRLIDTAAAYGNEAAVSRAIAASGIPRAQLFVTTKLATPDQGFTKSQDACNASLDRLGMDYVDLYLIHWPAPPVGQYVDAWGGMIQSRGEGHARSIGVCNFTEEHLSAIIDLTFVTPAVNQIELHPLLNQDEMRKSNAQHNVITQSYTPLVLGRLMDNSTLTAIAAEYGKTPAQVLLRWNLQLGNAVVFRSAKAEHIASNFDVFDFELAVNHMDAMNELHDGTRLRPDPETYAGS
What are the official names of this protein?
Uncharacterized oxidoreductase ML1669.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
Protein: CE63A_XENLA
Sequence: MEALLQGLQRQDRMGALQDSCEAELQELMKQIDIMLDHKRSQWEAETETMKTRLELKEQELNCALDREERLNQEVRRLRQQLIQQEEETQNKTTQYEAQLSGFKEELNRLKKSYEKVQKKHLRSEMKAKAEEERSEVSRLTRRLEEFRQRSLDWEKQRLLYQQQLAGLEAQRKTLIEQTEMYQHQSHNRKQMLEQTSLVGRSELQNLSGQLHRANDSLCAKEEELETLKIQLRCAVEGQKRAEHETELSKQAVQALKEEKAELRATLQAHTEFLQGSRVQKHELLPEGYRGSEVLRENNSIRSVEERLQEMGQVGGETEVEAIRSKLSVSRMNEHRLQAEVTCLEDSVESVTSQCQLLAKELKGKEEYFHGVKEDHQKCLSENKKLKGQLSQAELTHKSVLDGMRKEISQLTQELHQRDIRMASSAGIDWERKIKAERQRAEREAAEHRMSLNALENLRQENCRLSELLQTQEPDVAQALVNLEQANQRLQRELLQTQEKLELIAQRRESEIQNAVDSISQELLNKQEQELRIMQERLKVYEQEMQTFRSQQDAASSGSSLESIFSEVWKEQATGSPISAASVDSAIEPVEDLASSLPVPPTSPANAVASRFLQEEEQRSHELLQRLNAHIEELKQESQRTVEHFTQAR
What is the function of this protein?
Required for normal spindle assembly (PubMed:19182792).  Plays a key role in mother-centriole-dependent centriole duplication (PubMed:19182792).  Plays a role in DNA damage response (PubMed:19182792).  Following DNA damage, such as double-strand breaks (DSBs), is removed from centrosomes; this leads to the inactivation of spindle assembly and delay in mitotic progression (PubMed:19182792).
What are the official names of this protein?
Centrosomal protein of 63 kDa-A, Cep63-A, Xcep63.
What is the protein family that this protein belongs to?
Belongs to the CEP63 family.
Protein: GP_RVFVZ
Sequence: MYVLLTILTSVLVCEAIIRVSLSSTREETCFGDSTNPEMIEGAWDSLREEEMPEELSCSISGIREVKTSSQELYRALKAIIAADGLNNITCHGKDPEDKISLIKGPPHKKRVGIVRCERRRDAKQIGRKTMAGIAMTVLPALAVFALAPVVFAEDPHLRNRPGKGHNYIDGMTQEDATCKPVTYAGACSSFDVLLEKGKFPLFQSYAHHRTLLEAVHDTIIAKADPPSCDLLSAHGNPCMKEKLVMKTHCPNDYQSAHHLNNDGKMASVKCPPKYELTEDCNFCRQMTGASLKKGSYPLQDLFCQSSEDDGSKLKTKMKGVCEVGVQALKKCDGQLSTAHEVVPFAVFKNSKKVYLDKLDLKTEENLLPDSFVCFEHKGQYKGTMDSGQTKRELKSFDISQCPKIGGHGSKKCTGDAAFCSAYECTAQYANAYCSHANGSGIVQIQVSGVWKKPLCVGYERVVVKRELSAKPIQRVEPCTTCITKCEPHGLVVRSTGFKISSAVACASGVCVTGSQSPSTEITLKYPGISQSSGGDIGVHMAHDDQSVSSKIVAHCPPQDPCLVHDCIVCAHGLINYQCHTALSAFVVVFVFSSIAIICLAILYRVLKCLKIAPRKVLNPLMWITAFIRWIYKKMVARVADNINQVNREIGWMEGGQLVLGNPAPIPRHAPIPRYSTYLMLLLIVSYASACSELIQASSRITTCSTEGVNTKCRLSGTALIRAGSVGAEACLMLKGVKEDQTKFLKLKTVSSELSCREGQSYWTGSFSPKCLSSRRCHLVGECHVNRCLSWRDNETSAEFSFVGESTTMRENKCFEQCGGWGCGCFNVNPSCLFVHTYLQSVRKEALRVFNCIDWVHKLTLEITDFDGSVSTIDLGASSSRFTNWGSVSLSLDAEGISGSNSFSFIESPGKGYAIVDEPFSEIPRQGFLGEIRCNSESSVLSAHESCLRAPNLISYKPMIDQLECTTNLIDPFVVFERGSLPQTRNDKTFAASKGNRGVQAFSKGSVQADLTLMFDNFEVDFVGAAVSCDAAFLNLTGCYSCNAGARVCLSITSTGTGSLSAHNKDGSLHIVLPSENGTKDQCQILHFTVPEVEEEFMYSCDGDERPLLVKGTLIAIDPFDDRREAGGESTVVNPKSGSWNFFDWFSGLMSWFGGPLKTILLICLYVALSIGLFFLLIYLGGTGLSKMWLAATKKAS
What is the function of this protein?
Plays a role for virus dissemination in mosquitoes.  May act as a structural virion protein in insects.
What are the official names of this protein?
Envelopment polyprotein, M polyprotein.
What is the protein family that this protein belongs to?
Belongs to the phlebovirus envelope glycoprotein family.
What are the subcellular locations of this protein?
[Glycoprotein N]: Virion membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein. Host endoplasmic reticulum membrane; Single- pass type I membrane protein. Note=Interaction between Glycoprotein N and Glycoprotein C is essential for proper targeting of Glycoprotein C to the Golgi complex, where virion budding occurs. SUBCELLULAR LOCATION: [Glycoprotein C]: Virion membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein. Note=Interaction between Glycoprotein N and Glycoprotein C is essential for proper targeting of Glycoprotein C to the Golgi complex, where virion budding occurs. SUBCELLULAR LOCATION: [Isoform NSm protein]: Host mitochondrion outer membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [NSm-Gn protein]: Host Golgi apparatus. Virion. Note=Localizes in virions maturing in cells of insect origin but not in cells of mammalian origin.
Protein: ATP6_RHIWR
Sequence: MAAESGKIDPMHQFMIEPLFGQGWSIAGHNIAFTNSAMWMVVTLAALLIFMIGGMKRDLVPGRWQAAVESFTGFVAGMMATNIGPEGKKFTPYVFSLFMFILIANIMGMMPTGVVGVHPFTVTSHLTVTGVLAVISFSIVLVVGFWRHGFHFFSLFVPHGTPGYMIPMIFVIELFSFLIRPFSLGLRLFVAMTAGHILMKVLAGFVINGINAGALTVAIVSIPSFILMIGITLLELLVCAIQAYVFALLTSLYLNDAINLH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DPO1_RICTY
Sequence: MTKKNTLLLIDGYGFVFRAYYAQQSLSSAKGEPVGALYGFTSMLLKLLSDFKPQYGAIVFDSGGKNFRHKIYQNYKANRPTPPEDLIGQLPLIRDVASHLNFAILEKNGYEADDIIATFATKTITLGKEVIIISSDKDLLQLMSKNIKIYDPIKCKYITEDDVIIKFGTTPDKLREVMALIGDRSDNIPGVPSIGPKTASSLITQFGSVENIFNSLDQISSIKQRKTLQNSREAALISWRLIGLDSNVDLDFNLNNLEWSHPNSEKLIGFLQKYGFKSLYKRVENLFYIKINDHEEIVDNKVTEAKEISNASELENFAKEAEKIGIFGIYLLQQKGNNCALILSLQNQSYIIKITNNNLFPYNDNIKNNNDWFSYIILNLLTNKSIKKITYSLKHLLKFYANQSHKITAIEDLELMQYTLSAGLVQKNLFAETLTKDNIINESAKIVINFISLYKQTLLALQKNKAFRLYREIDLPTCFILDKMEKIGIKVDANYLHQLSDEFGTEILKIEEEIFALSGTKFNIASQKQLSEILFKKMQLPSGNTLAKTSSYSTKAGILKKLSEDGYHIATLLLRWRQLTKLKNTYTDSLPKQINNITKRIHTTFLQTSTTTGRLSSQEPNLQNIPTRSSDGNKIRQAFIAEDGYKLISADYSQIELRILSHIANVDVLKQAFINKEDIHTQTACQIFNLQKHELTSEHRRKAKAINFGIIYGISAFGLAKQLNVSNGTAAEYIKQYFAEYKGMQEYMVQTKAYANRNGYVTNFFGRKCFIPLIHDKKLKQFAERAAINAPIQGTSADIIKIAMIKLAQEIEKRKLKTRLILQIHDELLFEVPEIELELVIPIIKKIMEYSTNIDVPIITEIRAGNNWKEIH
What is the function of this protein?
In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
What are the official names of this protein?
DNA polymerase I, POL I.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-A family.
Protein: RCSA_ECOLI
Sequence: MSTIIMDLCSYTRLGLTGYLLSRGVKKREINDIETVDDLAIACDSQRPSVVFINEDCFIHDASNSQRIKLIINQHPNTLFIVFMAIANVHFDEYLLVRKNLLISSKSIKPESLDDILGDILKKETTITSFLNMPTLSLSRTESSMLRMWMAGQGTIQISDQMNIKAKTVSSHKGNIKRKIKTHNKQVIYHVVRLTDNVTNGIFVNMR
What is the function of this protein?
Component of the Rcs signaling system, which controls transcription of numerous genes.  Binds, with RcsB, to the RcsAB box to regulate expression of genes involved in colanic acid capsule synthesis.
What are the official names of this protein?
Transcriptional regulatory protein RcsA, Colanic acid capsular biosynthesis activation protein A.
What is the protein family that this protein belongs to?
Belongs to the RcsA family.
Protein: SYS_PYRAB
Sequence: MLDIKLIRENPELVKNDLKKRGELEKIKWIDEILKLDAEWRAKLKEINKLRHERNKIAIEIGKRRKKGEPVEELLAKSKEIVKRIESLEKEVEELKKKIDYYLWRLPNITHPSVPIGESEEDNVPIRFWGKARVWEGHLERFLEQSQGKMEYEVLEWRPKLHVDLLEILGGADFARAAKVSGSRFYYLLNEIVILDLALIRFALDELIKKGFTPVIPPYMVRRFVEEGSTTFEDFEDVIYKVEGEDLYLIPTAEHPLAGMHANEILDGKDLPLLYVGISPCFRKEAGTAGKDTKGIFRVHQFHKVEQFVYSRPEESWEWHERIIRNAEELFQKLEIPYRVVNICTGDLGYVAAKKYDIEAWMPGQGRFREVVSASNCTDWQARRLNIRFRDRTDEKPRYVHTLNSTAIATSRAIVAILENHQEEDGTVKIPKVLWKYTGFKEIVPVEKKERCCSS
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC2_NOSS1
Sequence: MTNEKMIFRNRVVDKGQLRNLISWAFTHYGTARTAVMADKLKDLGFRYATRAGVSISVDDLMVPPSKRSLLEAAEEEIRATEVRYQRGEITEVERFQKVIDTWNGTSEALKDEVVTHFKQTNPLNSVYMMAFSGARGNISQVRQLVGMRGLMADPQGEIIDLPIKTNFREGLTVTEYIISSYGARKGLVDTALRTADSGYLTRRLVDVSQDVIIREIDCGTTRGIPVRPMTEGSKTLIKLSTRLLGRVVGEDVIHPKTKEVIAPRNTPISDDLAKEIEKAGVAEVVVRSPLTCEAARSVCQHCYGWSLAHAKMVDLGEAVGIIAAQSIGEPGTQLTMRTFHTGGVFTGEVAQQVRSKMDGTIKLPRKLRTRTHRTRHGEDALFVESNGIMILEPRKEGSETPAPQEIHVTQGSTIYIVDGQQVKKGQLLAEVALGGRTTRTNTEKAVKDVASDLAGEVKFAEVVPEQKTDRQGNTTTTAARGGLIWILSGEVYNLPPGAELVVKNGDRVETNGVLAETKLTTIHGGVVRLPEATPGKSTREIEIITASVVLDQATVTVQSSQGRNNYLITTGNNQVFNLRATPGTKVQNGQVVAELIDDRYRTTTGGFLKFAGVEVQKKGKAKLGYEVVQGGTLLWIPEETHEVNKDISLLLVEDGQYVEAGTEVVKDIFCQNSGVVEVTQKNDILREVVVKPGELLMVDDPEAVIGRDNTLLQPGEELLGQVATELRYIQYVESPEGPALLSRPVVEFAVPSNPDVPSTTSVSQQTGRSIQMRAVQRLPYKDSERVKSVEGVELLRTQLVLEIEQEGEQEHNASPLAADIELIPDLEDADVQRLQLVILESLVLRRDIAADATQGSTQTSLEVKDGDTIVPGSVVARTQILSKEGGIVRGVQKGSEAVRRCLVLRHSDMATLNISAKPKVKAGDLIVAGTELAPGIFAEESGQIVGVKNAGESTTTQDAALSTQNYAVTIRAGRPYRVSPGAVLQIEDGDLVQRGDNLVLLVFERAKTGDIIQGLPRIEELLEARKPKEACILAKRGGEVKVVYGDGDEAIAIKVIESNGVVTDYPLGPGQNLAMPDGSVVPAGQPLSDGPSNPHEILEVFFSLGSEDGVYACASHALQKVQTFLVNEVQMVYQSQGIDIADKHIEVIVRQMTNKVRIDDGGDTTMLPGELVELRQVEQVNEAMAITGGARAQYTPVLLGITKASLNTDSFISAASFQETTRVLTEAAIEGKSDWLRGLKENVIIGRLIPAGTGYNTYDEPGMLEDYSTLETTSVLDETDDPLDMVLDDRTARAYNLDSPGLAETGFNNRRSILDDDELIADEIHDLVEAEVEVDDEVDDDYEDDDEDDDDYED
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
Protein: ENOPH_NAEGR
Sequence: MSAVKRISVSKYKTFMFDIEGTTTPIVFVAENLFPYIRKSLKTHIEETWESEETKKDVLSLKEQAEQDANSQSDFKDAPQINIDSQQSVIDNVVYNMDKDRKMTALKQLQGHMWRSGYESGNILGEVYDDAFDFFERIKKQGKNIYIYSSGSVQAQKLLFQYSTHGNLLPYFVDHFDTSNIGNKLEKSSYVKILERTGIPNSDILFLTDNIGEAIAAREAGIDSVLSVRPGTMKLPEDHTFEAVTSFEHLEF
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MNMA_CAMJJ
Sequence: MKILVAMSGGVDSTVTAYKLKNLGHEVIGCYMKLHGKPNYHEENIKKVEKVANFLQIPYHILDLQEDFKNKVYMPFVDTYKEGKTPNPCALCNRFIKLGKLLEFAKSLGCEKLATGHYARLENNLIKTAVDESKDQSYFLASADKEALKYLIFPLGEMKKEDVKKFASTIEVLKSFATQKESSEICFVEDTYVQVLDQFMDTKIPGEVLDSSGKVVGKHEGYMHYTIGKRRGFEVRGAHEPHFVLKINPKQNQIIVGTKEELKISEFNLKNINLFIDAKELDCEVKIRYRSKSTPCKVEIYEDKSAKITLKDPVYGLASGQMAVFYDHDKVIASGFIE
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENGB_THISH
Sequence: MNPFYQQARFLISAARPDAFPTDEGMEVAFAGRSNAGKSSAINVLCNQRALARTSKTPGRTQLINFFALDESRRLVDLPGYGYAKVPEAMRKAWRKLMEHYLGERACLKGLVVVMDIRHPLTDHDWTMLGWARERGLAVHVLLTKADKIRRGPAMDTARQVARALGDAGIEATVQPFSALKREGVEDAHGILDQWLGLTAEPEARAASE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: ARAC_CITFR
Sequence: MAETQNDPLLPGYSFNAHLVAGLTPIEANGYLDFFIDRPLGMKGYILNLTIRGEGVINNQGKQFVCRPGDILLFPPGEIHHYGRHPDASEWYHQWVYFRPRAYWQEWLTWPAIFAQTGFFRPDEAHQPHFNELFGQIINAGQGEGRYSELLAINLLEQLLLRRMEAINESLHPPMDNRVRDACQYISDHLADSNFDIASVAQHVCLSPSRLSHLFRQQLGISVLSWREDQRISQAKLLLSTTRMPIATVGRNVGFDDQLYFSRVFKKCTGASPSEFRAGCE
What is the function of this protein?
Transcription factor that regulates the expression of several genes involved in the transport and metabolism of L-arabinose.
What are the official names of this protein?
Arabinose operon regulatory protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPR3C_RAT
Sequence: MSCTRMIHVLDPRPLTSSVMPVDMAMRICLAHSPPLKSFLGPYNGLQRRHFVNKPKPLKPCLSVKQEAKSQKEWKSPHSQAKKRVVFADSKGLSLTAIHVFSDLPEEPAWDLQFDLLDLNDISSSLKLHEEKNLVFDFPQPSSDYLSFRDRFQKNFVCLENCSLQDRTVTGTVKVKNVSFEKKVQVRITFDTWKTYTDVDCVYLKNVYGSSDSDTFSFAIDLPRVIPTEEKIEFCISYHANGRVFWDNNEAQNYRIVHVQWKPDGVQTQVAPKDCAFQQVPLKTELEPTVFGSPRLASGLFPEWQSWGRVENLASYR
What is the function of this protein?
Acts as a glycogen-targeting subunit for PP1 and regulates its activity.  Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown.  Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in a variety of cell types (By similarity).
What are the official names of this protein?
Protein phosphatase 1 regulatory subunit 3C, Protein phosphatase 1 regulatory subunit 5, PP1 subunit R5, Protein targeting to glycogen, PTG.
Protein: DNAK_LEPIN
Sequence: MSKEKIIGIDLGTTNSVVSVMEGGDPVVIQNSEGARTTPSIVAFTAKGETLIGQFAKNQAITNAVNTIRSAKRFIGRRLNECESEMKHVSYKVIRSGNEGVKFETSAGEFTPQEISARVLMKMKQTAEDYLGQKVTKAVITVPAYFNDEQRQATKDAGRIAGLEVERIINEPTAAALAYGFDKKNVNSKIAVYDLGGGTFDISILELADGVFEVKSTNGDTHLGGDDFDMAIMEWMISEFKNQTGIDISADKNTVQRLKEAAEKAKIELSGTMSTQINLPFITADASGPKHLDMTLTRAKFDQLTKSLVDRTRIPCENALRDAGLKASDINEVILVGGSIRIPAVQELVKQVFGKEPNKSVNPDEVVAIGAAIQGGVLAGEVSDVLLLDVTPLSLGIETLGGVMTKLIERNTTIPTKKSQVFSTAADNQSAVSIHVLQGEREMASANRTLGRFDLIGIPPAPRGVPQIEVTFDIDANGIVHVSAKDLGTGKEQKIRIESSSGLSEDEIQKMVKDAEAHAAADKAQREVIEAKNELDTLTYSLEKTVNEAGDKIGANEKQLATDEIKRAREAIESNDKARIESAKASISKIATDIASKVYSQSAPGAEQAAAGGPNGSAGSNDQGNSTNNGEKVVDADYTVVDDEKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RS4_FUSNN
Sequence: MARNRQPVLKKCRALGIDPVILGVKKSSNRQIRPNANKKPTEYATQLREKQKAKFIYNVMEKQFRKIYEEAARKLGVTGLTLIEYLERRLENVVYRLGFAKTRRQARQIVSHGHIAVNGRRVNIASFRVKVGDIVSVIENSKNVELIKLAVEDATPPAWLELDRAAFSGKVLQNPTKDDLDFDLNESLIVEFYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: GNTK_XENTR
Sequence: MIIVIMGVSGSGKTVVGSQLAKKLGWNFYDADDYHPLENKEKMSQGTPLNDQDRHPWLCELHEIMMREKALGQHVVLACSALKRAYRSTLLTGSTPHWPENYQENDDLSSDTLFVHLHGSLEILSRRLLERKGHFMPRTLLDSQIDTLEPPSAPERFIAIDVDKDISVIVSEIEGEVDRKMMLVKSAQKD
What are the official names of this protein?
Probable gluconokinase, Gluconate kinase.
What is the protein family that this protein belongs to?
Belongs to the gluconokinase GntK/GntV family.
Protein: MATP_YERPB
Sequence: MKYQQLENLESGWKWAYLVKKHREGEAITRHIENSAAQDAVEQLMKLENEPVKVQEWIDAHMNVNLATRMKQTIRARRKRHFNAEHQHTRKKSIDLEFLVWQRLAVLARRRGNTLSDTVVQLIEDAERKEKYASQMSSLKQDLKDILDKEV
What is the function of this protein?
Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle.  Prevents early segregation of duplicated Ter macrodomains during cell division.  Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.
What are the official names of this protein?
Macrodomain Ter protein.
What is the protein family that this protein belongs to?
Belongs to the MatP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSH_LEPBJ
Sequence: MAETQAPAGYLFSEKHEWVKVEGDTALIGISDFAQSALGDIVFVDLPKSGKTVKQFETFGTIESVKAAEDLYAPVGGEVIESNSALSKNPGDVNSKPFDSWMIKVKGFSTSELEKLLSPEKYKALVAKLE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: PSAB_PROM3
Sequence: MATKFPSFSQGLAQDPTTRRIWYGIATAHDFESHDGMTEERLYQKLFSTHFGHLAVIGLWVAGNLFHIAWQGNFEQWVADPQNVQPIAHAIWDPHFGQGISDALTQAGASRPVNICYSGLYHWWYTIGMRTNTELYQGAIFIDILVAWLLFGGWLHLQPKFRPSLAWFKNAEAMMNHHLAVLFGFTNIAWTGHLVHVAIPESRGQHVGWDNFLTVLPHPEGLTPFFTGNWGAYAQNPDSLNHAFGTSEGAGTAILTFLGGVHPQSGALWLTDISHHHIAIGVFMIIGGHMYRNSFGIGHTFKEITDGHNTSHPNDPHKDGFREKIGHYGLSHTGITDTINNSLHFQLGLALACLGTAASLVAHHMGALPSYAFIAQDYTTQAALYTHHQYIAIFLMCGAFSHGAIFFVRDYDPEANKDNVLARVLETKEALISHLSWVCMLLGFHTLALYLHNDVVIAFGTPEKQILVEPIFAQFIQAASGKVMYGLDVLLANANSAPSLAAAGMPGDHYWMDLINASPEVSNFMPIGPGDFLVHHGIALGLHTTALILIKGALDARGSKLMPDKKDFGYAFACDGPGRGGTCDISAWDSTYMAIFWALNTIAWATYYWHWKHLAAWQGNMAQFNESSTHLMGWFRDYLWINSSQIINGYNPFGINNLSPWAYMFLAGHLVWATGFMFLISWRGYWQELIETLVWAHQRSPIANLVGWRDKPVALSIVQARLVGVTHFAVGNIFTFGAFVIASTASKFG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.