PharMolix/UniProtQA huggingface dataset:
Protein: UNC50_DROME
Sequence: MTQYSHVKYTQSPTPSVVSGYSSASRLHSPLPPPANHRRDCLSATTKSYKYLRRLLKFNQMDFEFALWQMLYLFVAPQKVYRNFNYRKQTKSQFARDDPAFLVLLVVCLCVTSLGFAYVLGLSFWQSISFIFYVVFVDCIFVGIIIASFFWAVTNRYLRTNSLEPDIEWGYAFDVHLNAFFPPLMLLHFIQLFFYNWLISQTWFISRFLGNTFWLMGMGYYVYITFLGYNCIPHLKNTRIILIALPIIFLLFLVVTIIGWNATISFVNFYKYRVY
What is the function of this protein?
Required for cell surface expression of acetylcholine receptors.
What are the official names of this protein?
Protein unc-50 homolog, Uncoordinated-like protein.
What is the protein family that this protein belongs to?
Belongs to the unc-50 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: RBL_ANTVS
Sequence: SVGFKAGVKEYKLTYYTPEYQTKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYRIERVVGEKDQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEALYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRMSGGDHIHSGTVVGKLEGERDITLGFVDLLRDDFVEQDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAQEGNAIIREACKWSPELAAACEVWKEIVFNFAAVDVLDK
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: EFG_MYCA9
Sequence: MAQDVLTDLNKVRNIGIMAHIDAGKTTTTERILYYTGVNYKIGETHDGASTTDWMEQEQERGITITSAAVTCFWNGNQINIIDTPGHVDFTVEVERSLRVLDGAVAVFDGKEGVEPQSEQVWRQADKYDVPRICFVNKMDKLGADFYFTVQTIKDRLGAKPLVIQLPIGAENDFEGIIDLVEMNAKVWRGETKLGESYETVEIPADLADKAAEYRNELLETVAESDEALLEKYLGGEELSIDEIKAGIRKLTVASELYPVLCGSAFKNKGVQPMLDAVIDYLPSPLDVESVKGHVPGHEDQEIERKPSTDEPFSALAFKIAVHPFFGKLTYVRVYSGKIESGAQVVNATKGKKERLGKLFQMHANKENPVETAAAGHIYAVIGLKDTTTGDTLCDPNSQIVLESMTFPDPVIEVAIEPKTKTDQEKLGTAIQKLAEEDPTFKVKLDQETGQTVIGGMGELHLDILVDRMRREFKVEANVGKPQVAYRETIRKKVENVEFTHKKQTGGSGQFAKVIVTVEPLVDAEDGATYEFENKVTGGRVPREYIPSVDAGAQDAMQYGILAGYPLVNIKVTLLDGAYHDVDSSEMAFKIAGSQALKKAAQAAQPVILEPLMAVEVITPEDYMGDVIGDLNSRRGQIQAMEERSGARVVKAQVPLSEMFGYVGDLRSKTQGRANYSMVFDSYAEVPANVSKEIIAKATGE
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHOQ_ECO57
Sequence: MKKLLHLFFPLSLRVRFLLATAAVVLVLSLAYGMVALIGYSVSFDKTTFRLLRGESNLFYTLAKWENNKLHVELPENIDKQSPTMTLIYDENGQLLWAQRDVPWLMKMIQPDWLKSNGFHEIEADVNDTSLLLSGDHSIQQQLQEVREDDDDAEMTHSVAVNVYPATSRMPKLTIVVVDTIPVELKSSYMVWSWFIYVLSANLLLVIPLLWVAAWWSLRPIEALAKEVRELEEHNRELLNPATTRELTSLVRNLNRLLKSERERYDKYRTTLTDLTHSLKTPLAVLQSTLRSLRSEKMSVSDAEPVMLEQISRISQQIGYYLHRASMHGGTLLSRELHPVAPLLDNLTSALNKVYQRKGVNISLDISPEISFVGEQNDFVEVMGNVLDNACKYCLEFVEISARQTDEHLYIVVEDDGPGIPLSKREVIFDRGQRVDTLRPGQGVGLAVAREITKQYEGKIVAGESMLGGARMEVIFGRQHSTPKDE
What is the function of this protein?
Member of the two-component regulatory system PhoP/PhoQ involved in virulence, adaptation to low Mg(2+) environments and the control of acid resistance genes.  In low periplasmic Mg(2+), PhoQ functions as a membrane-associated protein kinase that undergoes autophosphorylation and subsequently transfers the phosphate to PhoP, resulting in the expression of PhoP-activated genes (PAG) and repression of PhoP-repressed genes (PRG).  In high periplasmic Mg(2+), acts as a protein phosphatase that dephosphorylates phospho-PhoP, which results in the repression of PG and may lead to expression of some PRG (By similarity).
What are the official names of this protein?
Sensor protein PhoQ, Sensor histidine protein kinase/phosphatase PhoQ.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AACUN_ASPA1
Sequence: MTVSSAPYCLAGQVALVTGSGRGIGAAIAVELGRLGASVVVNYANSSAAAEKVVAEIQSLGSAAIAIQADVREVSQTVRLMDEAVAHFGGLDIVCSNAGVVSFGHLGEVTEEEFDRVFSLNTRGQFFVAREAYRHLNEGGRIILMSSNTAHDFSVPKHSLYSGSKGAIDSFVRVFAKDCGDKKITVNAVAPGGTVTDMFHAVSHHYIPNGEKYTAEERQQMAAHASPLMRNGFPLDIARVVCFLASKEGEWVNGKSLTVDGGAA
What is the function of this protein?
Atrochrysone carboxylic acid synthase; part of the gene cluster that mediates the biosynthesis of the tetrahydroxanthone dimer secalonic acid D (PubMed:30996871, PubMed:33891392).  The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase AacuL (Probable).  The atrochrysone carboxyl ACP thioesterase AacuM then breaks the thioester bond and releases the atrochrysone carboxylic acid from AacuL (Probable).  Atrochrysone carboxylic acid is decarboxylated by the decarboxylase AacuI, and oxidized by the anthrone oxygenase AacuG to yield emodin (Probable).  Emodin is then reduced to emodin hydroquinone by a yet unidentified oxidoreductase (Probable).  A-ring reduction by the short chain dehydrogenase AacuN, dehydration by the scytalone dehydratase-like protein AacuK and probable spontaneous re-oxidation, results in overall deoxygenation to chrysophanol (PubMed:33891392).  Baeyer-Villiger oxidation by the Baeyer-Villiger monooxygenase (BVMO) AacuH then yields monodictyphenone (PubMed:33891392).  Monodictyphenone is transformed into compounds with the tetrahydroxanthone skeleton via methylesterification by the methyltransferase AacuQ, followed by the action of the flavin-dependent monooxygenase AacuC, the isomerase AacuP, and the short chain dehydrogenase/reductase AacuF or AacuD (PubMed:33891392).  AacuF and AacuD should accept the same compound as a substrate but perform the ketoreduction with a different stereoselectivity, thus yielding blennolides B and A, respectively (PubMed:33891392).  In the final step of the biosynthesis, the cytochrome P450 monooxygenase AacuE accepts blennolide B and/or blennolide A to conduct the dimerization reaction to furnish the tetrahydroxanthone dimers, secalonic acids D, B, and F (PubMed:33891392).
What are the official names of this protein?
Short chain dehydrogenase/reductase AacuN, SDR AacuN, Secalonic acid biosynthesis cluster protein N.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: PUR5_BURP1
Sequence: MNPPKSAPDAQGLSYRDAGVDIDAGDALVDKIKPFAKKTLRDGVLGGIGGFGALFEVPKKYREPVLVSGTDGVGTKLKLAFHLNKHDTVGQDLVAMSVNDILVQGAEPLFFLDYFACGKLDVETAATVVKGIATGCELAGCALIGGETAEMPGMYPDGEYDLAGFAVGAVEKSKIIDGSTIAEGDVVLGLASSGIHSNGFSLVRKIIERANPDLSADFHGRSLADALMAPTRIYVKPLLALMEKIAVKGMAHITGGGLVENIPRVLRDGLTAELDQHAWPLPPLFQWLRQHGGVADAEMHRVFNCGIGMAVIVSAADADDALRQLADAGEQVWKIGTVRASREGEAQTVVV
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URK_BACLD
Sequence: MGKKPVVIGIAGGSGSGKTSVTRSIYEQFKGHSILMLEQDLYYKDQSHLPFEERLNTNYDHPLAFDNDYLIEHLNELLAYRPIKKPIYDYKLHTRSEEVVHVDPKDVIILEGILVLEDERLRDLMDIKLYVDTDADLRIIRRMLRDIKERGRSIDSVIEQYISVVRPMHNQFVEPTKRYADIIIPEGGQNRVAIDLMVTKIQTILEQNAIL
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYG_BOVIN
Sequence: MGLSDGEWQLVLNAWGKVEADVAGHGQEVLIRLFTGHPETLEKFDKFKHLKTEAEMKASEDLKKHGNTVLTALGGILKKKGHHEAEVKHLAESHANKHKIPVKYLEFISDAIIHVLHAKHPSDFGADAQAAMSKALELFRNDMAAQYKVLGFHG
What is the function of this protein?
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
What are the official names of this protein?
Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: Y1160_CALS8
Sequence: MILLETVIVTGMSGAGKSLAIRAFEDMGFFCIDNLPPQFLPKIAELASASNDKISRIAAVIDIRGGELFDDFKDVLNDLKKGTYNFKVLFLDAHDNVLVQRYKETRRKHPLSFESDGSILEAIQKEREKLEDIKRYADFIIDTSTLSPRDLKEKLFEIFSAQRSRETMLITVMSFGFKYGLPLDADLVFDVRFIPNPFYVEELKHKTGKEKEVKEYVLKWDVTKEFLKKLFDLILFLIPNYAEEGKAQLVIAIGCTGGKHRSVTIAEELFELIKNNGYKASIFHRDIEKDIKG
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Csac_1160.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: HUMMR_MOUSE
Sequence: MYLRRAVSKTLALPRRAPPGPAPLGKDASLRRMSSRKFPGTSGSNMIYYLVVGVTVSAGGYYTYKALTSKQVRRTEHVAEPKEQTKAELQPLPGEKEEHVAEAEQVCSEPGDTAVTEAESVDAEEVPEAAVVLPEESQASAPSEVPAEAAVVEASLSSSEPELKITEASLVETTESVPESTQEVESAAPDQDDVCNEGADTSQEGADTSQEGADTSQEGADTTKEEADNSKEAEGTTTEDPRSISEESAELEESPPLGSEPPAQPESQEEETQVTEETASPQG
What is the function of this protein?
Plays a role in the trafficking of mitochondria along microtubules (PubMed:19325000).  Regulates the kinesin-mediated axonal transport of mitochondria to nerve terminals along microtubules during hypoxia (PubMed:19325000).  Participates in the translocation of TRAK2/GRIF1 from the cytoplasm to the mitochondrion (PubMed:19325000).  Also plays a role in steroidogenesis through maintenance of mitochondrial abundance and morphology (PubMed:19528298).  Plays an inhibitory role during neocortex development by regulating mitochondrial morphology, distribution and motility in neocortical neurons (PubMed:24323429).
What are the official names of this protein?
Protein MGARP, Corneal endothelium-specific protein 1, CESP-1, Hypoxia up-regulated mitochondrial movement regulator protein, Mitochondria-localized glutamic acid-rich protein, Ovary-specific acidic protein.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side. Mitochondrion inner membrane; Single-pass type IV membrane protein; Cytoplasmic side. Note=Colocalizes with RHOT1, RHOT2, TRAK1 and TRAK2 at the mitochondrion.
Protein: ALGL_PSEE4
Sequence: MTIINRKTAPALLALALFGGAAQAALVPPQGYYEGIEKLKSSDGDFRCEAAPRPYTGSLRFRSKYEGSDKARATLNVASEKAFRASTKDITTLEKGVSKMVGQYMRDGRPAQLDCALTWLGTWARADALMSSDYNHTGKSMRKWALGSMSGSWLRLKFSNSQPLAAHQAEAEQIEKWFARLAQQTVRDWSGLPLEKINNHSYWAAWSVMATAVATDRRDLFDWAVKEYKVGANQVDEQGFLPNELKRRQRALAYHNYALPPLAMIASFAQANGVDLRKENNFALQRLGEGVLAGARDPSQFTAHAGVKQDLHDLKIDSKYAWLEPWCALYHCVGDTLERKHDMQPFDSFRLGGDVTRVYDPGAESKK
What is the function of this protein?
Catalyzes the depolymerization of alginate by cleaving the beta-1,4 glycosidic bond between two adjacent sugar residues via a beta-elimination mechanism.  May serve to degrade mislocalized alginate that is trapped in the periplasmic space.
What are the official names of this protein?
Alginate lyase, Poly(beta-D-mannuronate) lyase.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 5 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: GAL80_YEAST
Sequence: MDYNKRSSVSTVPNAAPIRVGFVGLNAAKGWAIKTHYPAILQLSSQFQITALYSPKIETSIATIQRLKLSNATAFPTLESFASSSTIDMIVIAIQVASHYEVVMPLLEFSKNNPNLKYLFVEWALACSLDQAESIYKAAAERGVQTIISLQGRKSPYILRAKELISQGYIGDINSIEIAGNGGWYGYERPVKSPKYIYEIGNGVDLVTTTFGHTIDILQYMTSSYFSRINAMVFNNIPEQELIDERGNRLGQRVPKTVPDHLLFQGTLLNGNVPVSCSFKGGKPTKKFTKNLVIDIHGTKGDLKLEGDAGFAEISNLVLYYSGTRANDFPLANGQQAPLDPGYDAGKEIMEVYHLRNYNAIVGNIHRLYQSISDFHFNTKKIPELPSQFVMQGFDFEGFPTLMDALILHRLIESVYKSNMMGSTLNVSNISHYSL
What is the function of this protein?
This protein is a negative regulator for the gene expression of the lactose/galactose metabolic genes.  It binds to GAL4 and so blocks transcriptional activation by it, in the absence of an inducing sugar.
What are the official names of this protein?
Galactose/lactose metabolism regulatory protein GAL80.
What is the protein family that this protein belongs to?
To K.lactis GAL80.
Protein: SAIA_LATSK
Sequence: MKADYKKINSILTYTSTALKNPKIIKDKDLVVLLTIIQEEAKQNRIFYDYKRKFRPAVTRFTIDNNFEIPDCLVKLLSAVETPKAWSGFS
What is the function of this protein?
Imparts immunity to sakacin-A to naturally sensitive host strains.
What are the official names of this protein?
Sakacin-A immunity factor.
Protein: CPFC_STAAW
Sequence: MTKKMGLLVMAYGTPYKESDIEPYYTDIRHGKRPSEEELQDLKDRYEFIGGLSPLAGTTDDQADALVSALNKAYADVEFKLYLGLKHISPFIEDAVEQMHNDGITEAITVVLAPHYSSFSVGSYDKRADEEAAKYGIQLTHVKHYYEQPKFIEYWTNKVNETLAQIPEEEHKDTVLVVSAHSLPKGLIEKNNDPYPQELEHTALLIKEQSNIEHIAIGWQSEGNTGTPWLGPDVQDLTRDLYEKHQYKNFIYTPVGFVCEHLEVLYDNDYECKVVCDDIGANYYRPKMPNTHPLFIGAIVDEIKSIF
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
What are the official names of this protein?
Coproporphyrin III ferrochelatase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIKR_ENT38
Sequence: MQRVTITLDDDLLETLDSLSQRRGYNNRSEAIRDILRGALAQETAQQHGTQGFAVLSYVYEHEKRDLARRLVSTQHHHHDLSVATLHVHVSHEDCLEIAVLKGDMGDIQHFADDVIAQRGVRHGHLQCLPDDE
What is the function of this protein?
Transcriptional repressor of the nikABCDE operon.  Is active in the presence of excessive concentrations of intracellular nickel.
What are the official names of this protein?
Nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: NIFH_ROSCS
Sequence: MRQVAFYGKGGIGKSTTQQNTAAALASMGYRLMVVGCDPKADCTRLLLRGVRQPSVLDTLRDVGPESVQLEKVVVQGYGGVKCVESGGPEPGVGCGGRGVITAIQTLETLGAYKDDLDYVFYDVLGDVVCGGFAMPIREGYAEEIYIVCSGEYMALFAANNICKGIKKFAERGYARLGGLVCNSRLVENEQALVKEFARRLNTKMIHFIPRSKDVQRAEINKKTVIDYDPDLPQAQEYRELARKIDENDEFTIPTPITQEELEDLMREYGIVD
What is the function of this protein?
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
What are the official names of this protein?
Nitrogenase iron protein, Nitrogenase Fe protein, Nitrogenase component II, Nitrogenase reductase.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: PDXB_SHIF8
Sequence: MKILVDENMPYARDLFSRLGEVIAVPGRPIPVAQLADADALMVRSVTKVNESLLAGKPIKFVGTATAGTDHVDEAWLKQAGIGFSAAPGCNAIAVVEYVFSSLLMLAERDGFSLHDRTVGIVGVGNVGRRLQARLEALGIKTLLCDPPRADRGDEGDFRSLDELVQRADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLTCLNEGQKLSVVLDVWEGEPELNVELLTKVDIGTPHIAGYTLEGKARGTTQVFEAYSKFIGHEQHVALDTLLPAPEFGRITLHGPLDQPTLKRLVHLVYDVRRDDAPLRKVAGIPGEFDKLRKNYLERREWSSLYVICDDASAASLLCKLGFNAVHHPAR
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA_BACMK
Sequence: MTKITVIGAGSWGTALAMVLADNGHDVRIWGNRPELMNEINTKRENSRYLPGITLPSTIVAYSSLEEALVDVNTVLLVVPTKAYRDVLQEMKEIVTEPITWIHASKGIEPGTSKRISEVIEEEIPESLIKDVVVLSGPSHAEEVGLHQATTVTSAAKRMEAAEGVQDLFMNSYFRVYTNPDIVGVELGGALKNIIALAAGISDGLGLGDNAKAALMTRGLTEIARLGRKMGGNPLTFAGLTGMGDLIVTCTSVHSRNWRAGNMLGKGHSLEEVLESMGMVVEGVRTTKAAHELAEKMEVEMPITAALYDVLFNGNNVKDAVGSLMGRVRKHEVEAIPDLL
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H34_STYLE
Sequence: QTGAKAPRKALANKAARKTAPADGGVKKPHRFRPGTVALREIRKYQKSTELLIRKLPFQRLVREIASDYKSDLRFQSSAVAAIQEAAEAYMVGLFEDTNLCAIHAGRVTIMP
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3-4.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: ARGJ_NEUCR
Sequence: MESLNGCVLSQLRQSGAQVTRTLQKIQSRSYSAPVSGSIPAAKKKYVPTSGTYPLGFSASGINVGVKPKNTTKPDVCLVASDRPCAAAAVFTKNKFQAAPVTFSRSLLQKKGNQGIQGVVVNSGCANAVTGKGGLEDAGKMAQAADECFGQSESTLVMSTGVIGQRLPIEKITSNIPRAHKAMGSTHDHWLTAAKAICTTDTFPKLISRSFKLPSSPSVEYRIAGMTKGAGMIHPNMATLLGIIATDAPVSSTVLPAVLKHAVDRSFNSITIDGDTSTNDTVALLANGAAGGKEVVANTPDYDAFQTVLTDFSTDLAKLIVRDGEGATKFVTIRVVEAASEEAARKIASTIARSPLVKTALYGKDANWGRILCATGYSLVSEPGLPVNDVSEVVPEKTNVSFIPTDGTAELKLLVNGEPEQVDEARAAEILELEDLEILVRLGTGDKQATYWTCDYSHEYITINGDYRT
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: PUR5_STRPJ
Sequence: MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFGGMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPLYFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAVGVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLKEVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVLPIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKENESVIIK
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_SALPA
Sequence: MRIILLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVKSGSELGKQAKDIMDAGKLVTDELVIALVKERIAQEDCRNGFLLDGFPRTIPQADAMKEAGIVVDYVLEFDVPDELIVDRIVGRRVHAASGRVYHVKFNPPKVEGKDDVTGEDLTTRKDDQEETVRKRLVEYHQMTAPLIGYYQKEAEAGNTKYAKVDGTQAVADVRAALEKILG
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CE85L_MOUSE
Sequence: MWGRFLAPEAGGRDSPSGARSFPAGSDYSSAWLPGNESLWQATAVPSNHRNNHLRRHSITSDSGDTGIGTSCSDSVEDHSTSSGTLSFKPSRSLVTLPTAHVMPSNSSASVSKHRESLTPDGSKWSTSLMQTLGDHSRGERDSSLDMKDFRPLRKWSSLSKLTAPDTRNHSGIAYPQELRNSLEMTGKGKPFMSHLRTFGPSCLHDSMELLKLEDKEINKKRSSTLDCKYKFESCNKEDVRVSSSALRRQTLDMTYSALPESKPIVTGSETFESPKYLMLGQQAVGGVPIQPSVRTQMWLTEQLRTNPLEGRTTDDSYSLAPWQQPQTEEFQQGSETPMQVLTGSSRQSYSPPGFQDFSKWESVLKIKEGLLRQKEIVIDRQKQQINHLHERIRDNELRAQHAMLGHYVNCEDSYVSNLQPQYESSSGQSLFTEQPLSHPHQEELEQKLASTEKEVLQLNEFLKQRISQFSEEKKKLEEKLKTRDRYISSLKKKCQKESEQNKEKQRRIETLEKYLADLPTLDDVQSQSLQLQVLEEKNKNLQETLIDTEKQLEEIKKQCQDKEVQLLCQKKKEKELVTSVQSLQQKVEKCLEDGIRLPMLDAKQLQSENDNLREQNATASKIIESQQDEINRMILEIQSMQGKLCEEKLTARSTVEELGRKEGSLQRLTEALLENQRQMGETYSLLDQGHEAEQSRPQTIHSKWPLFDLTVIDQLFKEMSYCLFDLKALCSILNQRAQGKEPNLSLLLGIRSMNCSAEETENDHSPETLTKKLSDVCQLRRDIDELRTTISDRYAQDMGDNCVTQ
What is the function of this protein?
Plays an essential role in neuronal cell migration.
What are the official names of this protein?
Centrosomal protein of 85 kDa-like.
What is the protein family that this protein belongs to?
Belongs to the CEP85 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localized specifically to the pericentriolar region.
Protein: CAPP_TRIV2
Sequence: MGSVLYSLSESANLYPASELFLRHRLQIVEELWESVLRQECGQNMVDLLRQLRDLCSPEGQATKDQAVSAVKLIEQLNINEAIRAARAFALYFQLINIIEQEYEQRQQLTRYSDLEAETAPLNGSENITSSSNHNEDDVIFNRGLGTDFLGKNWTNRGQGKQKGTFAALFPLLSKLNVPPQQIQRLISQLDVRLVFTAHPTEIVRHTIRDKQRQVVDLLQQLDEVENRAKEGGGYPWEAGEIREKLLEEIRLWWRTDELHQFKPTVLDEVDYALHYFQEVLFDGIPQLYKRFKYALNQTFSWLEPPSKDFCSFGSWVGSDRDGNPSVTPEITWQTACYQRKMVLERYIKSVKQLIELLSISMHWSDVLPDLLESLELDQSQLSEVYDALALRYRQEPYRLKLAYVLKRLENTRDRNLALYKGETPTNEDSPMYRSGAEFLAELRLIQHNLTETGLSCRELDNLICQVEIFDFNLTKLDIRQESTRHSDALNEILDYLQLLPQPYNDLSEEQRVAWLTTELQTRRPLISSELPFSDKTNDVIKTFRVVRSLQQEFGINICQTYIISMCRQVSDVLEVLLLAKEARLFDPAIAVGTIQVVPLFETVEDLQRSRSVMRQLFELPLYRALLAGGYKSTEVKVPSPESTPLPTPHSVLTPDLQEVMLGYSDSNKDSGFLSSNWEIHKAQKSLQKIAEEYGVNLRIFHGRGGSVGRGGGPAHEAILAQPGHSINGRIKITEQGEVLASKYSLLDLALYNLETITTAVIQASLLRTGFDDIEPWNEIMEELAARSRQHYRGLIYEQPDFIDFFHQVTPIEEISQLQISSRPARRPSGKKDLSSLRAIPWVFSWTQTRFLLPSWYGVGTALQEFFNEEPEEHLKLMRYFYVKWPFFKMVISKVEMTLAKVDMQMAGHYVQELSDPEDKSRFEKVFEQIANEYYLTRDLVLKITDHSRLLDGDPVLQRSVQLRNGTIVPLGFIQVSLLKRLRQSKNNNATSGVIHSRYSKGELLRGALLTINGIAAGMRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: DER_RICFE
Sequence: MTKKIITLVGRPNVGKSTLFNRLSIRKKAIVHDLPGVTRDRKYTEGKIGSFEFLLIDTPGLEENPDSMGERLIEQTTKAILEADLICFMVDGRSGILPDDKLLGSFVRKYNKPAILIVNKCEKAFDFDKEYYKLGFDSMVAISAEHGTGLIDLYDEIIAKLPEEESIETNIADPIKRDCLQIVVSGRPNAGKSTFINALINDERLLTGPEAGITRESIEIDWQYKNNHIKLIDTAGLRKKSTITESLEKLSASDAINSIKFANTVILMIDALAPLKQQDLNIASHVVNEGRSIVIVVNKWDLVKESEKEAFQEEFYYQINTHLPQVKGVPVLFISAINKQNIEQVLDACLKIYKIWNKKITTSKLNEWLNFTTEAHPLPLQKGGKRVRVKYMTQTKTRPPTFKLFSNNPEKITDSYTRYLVNNMREAFDMPGIPIRFTYVKTKNPYV
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: TRPC_JANMA
Sequence: MSDILNKILDVKADEVAAAKKYRSLASLRDEVEGNKEARAAIRGFEASLRAKIAAGQAGIIAEIKKASPSKGVIRPDFHPADIAVSYEKNGAACLSVLTDVQFFQGAPEYLKQARTACALPALRKDFMIDPYQLYEARSWGADCILLIVAALDHGLMAELEACAHELGMNVLVEVHNAEELTAALKLKTSLLGVNNRNLRTFETSLQTTLDLLPRISPDKLVITESAIVTPDDVKKMRDADVHAFLVGEAFMRAPDPGVELGRLFN
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.