PharMolix/UniProtQA huggingface dataset:
Protein: PANB_HELPY
Sequence: MSMQTAPIKKITLNHLQAKKNQEKIIAITAYDALFAQIFDPLVDVILVGDSLNMSFFNQNDTLSASVEMMLYHTKAVCAGAKTPFIITDMPFGSYKDEKTALKNAIRVYKETQASAIKLEGGKEKAKLVKTLTNEGVIVVGHIGLMPQFVRLDGGYKIKGKNEEQQKKLLEDALSLEEAGVGLLVLEGITTPIAQKITQKIKIPTIGIGSGKDCDGQILVWSDMLGFFDSFKPKFVREYLKGKELIQNAIKQYADDVKKGNFPNELESYH
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_ERYLH
Sequence: MSDDTKKQDTAADAEVEKEMEGVPEHLRDDRGSEEDASDDLSAALESLKSDLEAAKQETLYAKAETQNVRRRMEKDIQDARTYAATGFARDILSIADNLARAIDAIPQELREDEKFKGLVAGIEATQRELDKVFAQHGVSRIAAMGLPLDPNQHQAMMEVPTDEVEPGTIVQEMQAGYMIRDRLLRPSMVGVAKKPD
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_VIBC3
Sequence: MQVTVETLEGLQRRLNITVPAANIEDAVAAELRNIAKNRRFDGFRKGKVPMKMVAKMYGKAVRQDVLGEVMQRHFIEAIVKEKINPAGAPTFAPVEIGEGKDLVFTATFEVYPEVELKGLENIAVEKPAAEVTDADVAEMLETLRKQQATWKEVDEAAENGKRVSIDFVGSIDGVEFEGGKAENFPLEMGAGRMIPGFEDGIVGKTKGMEFVIDVTFPEDYHAENLKGKAAKFAIKVNKVEARELPELNDEFVARFGVAEGGVDALKAEVRKNMERELKQAIKARIKEQAIEGLVKENEIQVPSALIDQEINVLRQQAAQRFGGNVEAAAQLPRELFEEQAKRRVVVGLLLGEVIRTHELKADEEKVKALITEMATAYEDPSEVVSYYEQNQQLMNNMRNVALEEQAVDAIIAKAKVTEKAISFSELMNPVAA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: DNAK_SHIFL
Sequence: MGKIIGIDLGTTNSCVAIMDGTIPRVLENAEGDRTTPSIIAYTQDGETLVGQPAKRQAVTNPQNTLFAIKRLIGRRFQDEEVQRDVSIMPFKIIAADNGDAWVEVKGQKMAPPQISAEVLKKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRIAGLEVKRIINEPTAAALAYGLDKGTGNRTIAVYDLGGGTFDISIIEIDEVDGEKTFEVLATNGDTHLGGEDFDSRLINYLVEEFKKDQGIDLRNDPLAMQRLKEAAEKAKIELSSAQQTDVNLPYITADATGPKHMNIKVTRAKLESLVEDLVNRSIEPLKVALQDAGLSVSDIDDVILVGGQTRMPMVQKKVAEFFGKEPRKDVNPDEAVAIGAAVQGGVLTGDVKDVLLLDVTPLSLGIETMGGVMTTLIAKNTTIPTKHSQVFSTAEDNQSAVTIHVLQGERKRAADNKSLGQFNLDGINPAPRGMPQIEVTFDIDADGILHVSAKDKNSGKEQKITIKASSGLNEDEIQKMVRDAEANAEADRKFEELVQTRNQGDHLLHSTRKQVEEAGDKLPADDKTAIESALTALETALKGEDKAAIEAKMQELAQVSQKLMEIAQQQHAQQQTAGADASANNAKDDDVVDAEFEEVKDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: NX22A_DANRE
Sequence: MSLTNTKTGFSVKDILDLPDTNDEEGSITGTEEDTEGSEATKTPGVLVQSPLENVQNLPLKNPFYDNSDNPYTRWLATTDSIQYSLHGLSANSQDTSAKSPEPSADESPDNDKETSSNGSDSGKKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKMKRARAEKGMEVTHLPSPRRVAVPVLVRDGKPCHTLKAQDLAATFQAGIPFSAYSAQSLQHMQYNAHYSAATTPQFPTAHHLVQTQQWTW
What is the function of this protein?
Transcriptional activator involved in the development of insulin-producting beta cells in the endocrine pancreas (By similarity).  May also be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance.  Binds to elements within the NEUROD1 promoter (By similarity).
What are the official names of this protein?
Homeobox protein Nkx-2.2a, Homeobox protein NK-2 homolog B-A.
What is the protein family that this protein belongs to?
Belongs to the NK-2 homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: THIC_PROMT
Sequence: MRNSWVASRKGKTNVSQMHFARKGEITEEMRYVAKRENLPESLVMEEVARGRMVIPANINHMNLEPMAIGIASTCKVNANIGASPNASDISEELKKLDLAVKYGADTLMDLSTGGVNLDEVRTEIINASPIPIGTVPVYQALESVHGSISRLNEDDFLHIIEKHCQQGVDYQTIHAGLLIEHLPKVKGRITGIVSRGGGILAQWMLYHYKQNPLFTRFDDICEIFKRYDCTFSLGDSLRPGCLHDASDEAQLAELKTLGELTRRAWKHDVQVMVEGPGHVPMDQIEFNVRKQMEECSEAPFYVLGPLVTDISPGYDHISSAIGAAMAGWYGTAMLCYVTPKEHLGLPNPEDVREGLIAYKIAAHAADVARHRSGARDRDDELSKARKEFDWNKQFELSLDPERAKQYHDETLPEEIFKKAEFCSMCGPNHCPMNTKITDEDLDKLNDQIQSKGAAELTPVKLNKEN
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: TSN6_MOUSE
Sequence: MASPSRRLQTKPVITCLKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKATNVPFVLIGTGTVIILLGTFGCFATCRTSAWMLKLYAMFLTLIFLVELVAAIVGFVFRHEIKNSFKSNYENALKEYNSTGDYRSEAVDKIQSTLHCCGVTNYGDWKGTNYYSETGFPKSCCKLEGCYPQRDADKVNEEGCFIKVMTTIESEMGVVAGISFGVACFQLIGIFLAYCLSRAITNNQYEIV
What are the official names of this protein?
Tetraspanin-6, Tspan-6, Transmembrane 4 superfamily member 6.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CNTLN_RAT
Sequence: MNLQDELDELKIYMTIDKTTIQELNRCMAEKREEQLFRHHEDAGVKKSTPEKNEKAISEQTLEKVIELENRLKSFEKNSRKLKEESKKLKKENDFLKSHLQHYQEDSESRGKELEKLLRVSSSVEQDKSELQTKVTALEREVTTLRRQVAKAKALRDENEEVVNPEEKEHCPTDKAKSEMATTDVRAQHCDCKTTTTKVKFKAAKKKCSVGRHHTVLNHSIKVMSHVENLSKDGWEDMSEGSSDSETQTFQNLGTVIVETSQNIRPIENDGNQKETDQTEDSRAQQEVQTYSCEDLKAPQNTKKMTFQNKSGSLQKNLHSALPARVNREKCKTKPAQKSSSNTILLRERIVSLQQQNSLLQNARKAAESSAKEFKEANEKLLHQQQISDHRFQTSRQTIKLTLDLAELRKEKEDLLKKVESSSDITSLAEEVSRIMAPQIQVTTLGPSRSTDLEIKQLQCKLKNATNELTKQSSSVKSLKLELLAKDDHMKAMQEKMSRMERDITMKRHLIEDLKFRQKINSESNESFNEMLGTLEKKDLKMNLLISKLNDTETAMAQIKSAASEQLQGLALQSEQVLEGTQKKLLLANEKIEEFTVFVQALVNELQSDAHRTRQQVRELRQTQKSRHACKTSTHKAQTLAASILNISRSDLEEILHTGDEMEIEKTKIDAENDKDWMLYIQKLLQGQLPFASYLLEAVLGKIKENKKLTEGYFTVMKDIK
What is the function of this protein?
Required for centrosome cohesion and recruitment of CEP68 to centrosomes.
What are the official names of this protein?
Centlein, Centrosomal protein.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Colocalizes with gamma-tubulin during interphase and mitosis (PubMed:18086554). Appears to associate with the mother centriole during G1 phase and with daughter centrioles towards G1/S phase (PubMed:18086554). Localizes to the proximal ends of the centrioles (By similarity). Levels are high at interphase centrosomes but are reduced on mitotic spindle poles (By similarity).
Protein: LPXD_YERPA
Sequence: MPSIRLADLAQQLDAQVHGDGDLVITGIASMHSAQPEQITFLSNSRYREQLASCNAGAVVLTEADLPFCKVAALVVENPYFTYARMAQIMDTTPQPAQDIAPSAVISPQATLGEGVSVGANAVIESGVVLGDNVVIGAGCFIGKNTHIGAGSRLWANVSIYHEVVIGQNCLIQSGTVIGADGFGYANDRGNWVKIPQLGSVHIGDRVEIGACTTIDRGALDNTIIGNGVIIDNQCQIAHNVVIGDNTAVAGGVIMAGSLKVGRYCMIGGASVINGHMEICDKVTITGMGMVMRPITEPGLYSSGIPLQPNKMWRKTAALVMNIDGINKRLKAVERKIDKE
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-(hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase, UDP-3-O-(3-OHC14)-GlcN N-acyltransferase, UDP-3-O-(3-hydroxytetradecanoyl)glucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: LON_PARUW
Sequence: MLEEPIDALETEFENALNSLEDNQLSKINGQLPEQVHVFPLLRRPFFPGMAAPLVIEPGPFYEVLKVVAKSDHKCVGLVLTRSEQAEIYKVGFSDLYQIGVLARVLRIIPMEQGGAQVILNMERRIKIEKPTSETKTLKANVSYIEDDPILTTELKAYAISILSTIKELLKLNPLFKEELQIFLGHSDFTEPGKLADFAVALTTASREELQDVLETFDIRKRIDKALILLKKELDISILQHNINQKIEATINKSQKDFFLREQLKTIKKELGIERDDKSLDREKFEARLKERVVPSDVMKVITEELEKLSVLDMQSAEYSVVRGYLDWLTTIPWGIYSQENHNLEEAEKILAHDHYGLEDIKQRILEFIGVGKLAKGVRGSIICLVGPPGVGKTSIGKSIARALNRKFYRFSVGGMRDEAEIKGHRRTYVGAMPGKMIQALKYCQTMNPVIMLDEVDKMGKSFQGDPASALLEVLDPEQNAEFLDHYLDVRCNLSEVLFIVTANVLDTIPEPLKDRMDILRLSGYIMQEKLEIAKKYLIPRNRKEMGLKALEVSFTQEALRSIINGYARESGVRNLENLLKKILRKLAVNIVREQEEHDKEQAKKKKSSRSKKPIAFVPTKHSITPSNLKDFLGKPVFTSDRFYERTPVGVCMGLAWTAMGGATLYIESIKVAGEKTVMKLTGQAGDVMKESAEIAWSYVHSSIHKYAPGYTFFEKSQVHIHIPEGATPKDGPSAGITMVTSLLSLILDTPVLDNLGMTGELTLTGRVLPIGGVKEKLVAARRSGLKVLIFPKDNLRDYEELPEYIRKGITVHFVDHYDQVFKISFPNKHQMKLC
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner.
What are the official names of this protein?
Lon protease, ATP-dependent protease La.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CXCR2_BOVIN
Sequence: MTIILKDLSNSSILWEGFEDEFGNYSGTPPTEDYDYSPCEISTETLNKYAVVVIDALVFLLSLLGNSLVMLVILYSRIGRSVTDVYLLNLAMADLLFAMTLPIWTASKAKGWVFGTPLCKVVSLLKEVNFYSGILLLACISMDRYLAIVHATRTLTQKWHWVKFICLGIWALSVILALPIFIFREAYQPPYSDLVCYEDLGANTTKWRMIMRVLPQTFGFLLPLLVMLFCYGFTLRTLFSAQMGHKHRAMRVIFAVVLVFLLCWLPYNLVLIADTLMRAHVIAETCQRRNDIGRALDATEILGFLHSCLNPLIYVFIGQKFRHGLLKIMAIHGLISKEFLAKDGRPSFVGSSSGNTSTTL
What is the function of this protein?
Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor.  Binding of IL-8 to the receptor causes activation of neutrophils.  This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.  Binds to IL-8 with high affinity.  Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
What are the official names of this protein?
C-X-C chemokine receptor type 2, CXC-R2, CXCR-2, High affinity interleukin-8 receptor B, IL-8R B.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SRP54_THEON
Sequence: MALEKLGKALNNALRKLARSSTVDEATIKEVVRDIQRALIQADVNVRLVLDLTKRIEKRALEEEPPTGVSKKEHIIKIVYEELTKFLGTEAKPIEIKEKPTVLLTVGIQGSGKTTSIAKLARYFQKRGYKVGLVCSDTWRPGAYQQLKQLVEPFGIEVFGDPEEKDAIKLAKEGVEHFREKGVDIIIVDSAGRHKEEKSLIEEMKQISAAIKPHEVILVIDGTIGQQAYNQALAFKEATPIGSIIVTKLDGSAKGGGALSAVAATGAPIKFIGVGERIDDLEPFDPKRFVSRLLGLGDIQGLLEKFEELQKQQEFREEDLEKFLKGKFNLKDMYAQLEAMQKMGPLKQILQMIPGMGYSLPDDAVRVGEERLKKFKVIMDSMTEEELEHPEIINYSRIKRIARGSGTSIQEVRELLHQYNQMKKMFKSMDKRKLSKMARKFNLGGFGL
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes.  The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
What are the official names of this protein?
Signal recognition particle 54 kDa protein, SRP54.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. SRP54 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=The SRP-RNC complex is targeted to the cytoplasmic membrane.
Protein: CP125_MYCS2
Sequence: MPTPNIPSDFDFLDATLNLERLPVEELAELRKSEPIHWVDVPGGTGGFGDKGYWLVTKHADVKEVSRRSDVFGSSPDGAIPVWPQDMTREAVDLQRAVLLNMDAPQHTRLRKIISRGFTPRAIGRLEDELRSRAQKIAQTAAAQGAGDFVEQVSCELPLQAIAELLGVPQDDRDKLFRWSNEMTAGEDPEYADVDPAMSSFELISYAMKMAEERAVNPTEDIVTKLIEADIDGEKLSDDEFGFFVVMLAVAGNETTRNSITHGMIAFAQNPDQWELYKKERPETAADEIVRWATPVSAFQRTALEDVELGGVQIKKGQRVVMSYRSANFDEEVFEDPHTFNILRSPNPHVGFGGTGAHYCIGANLARMTINLIFNAIADNMPDLKPIGAPERLKSGWLNGIKHWQVDYTGAGKASVSGAPGTCPVAH
What is the function of this protein?
Involved in the utilization of cholesterol as the sole carbon and energy source by degrading the side chain.  Primarily catalyzes the sequential oxidation of the terminal methyl of cholest-4-en-3-one into (25S)-26-hydroxycholest-4-en-3-one (alcohol), (25S)-26-oxocholest-4-en-3-one (aldehyde), to finally yield the carboxylic acid (25S)-3-oxocholest-4-en-26-oate.  Also able to sequentially oxidize cholesterol itself, not only cholest-4-en-3-one.
What are the official names of this protein?
Steroid C26-monooxygenase, Cholest-4-en-3-one C26-monooxygenase, Cholest-4-en-3-one C26-monooxygenase [(25S)-3-oxocholest-4-en-26-oate forming], Cholesterol C26-monooxygenase, Cholesterol C26-monooxygenase [(25S)-3beta-hydroxycholest-5-en-26-oate forming], Cytochrome P450 125, Steroid C27-monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: RBSA2_RHIEC
Sequence: MAEPVLTIHGVTKHFGAVKALRDVDFTLERGEVHALCGENGAGKSTLMNIIAGVLQPTEGEIRVDGKAVRISSPAAAQYLGIGLVHQEIALCPDATVAENMFMAATNRRRAPLMNYRRLERDAQAVMNRLAAIDVRRRVADLPISSQQLVEIAKALTLDCRVLILDEPTAALTETEAQQLFSIIRDLKANGISIIYISHRMAEIFSLCDRVTVFRDGRYVCTDRLADLTPDDVVRRMVGREITQLYPDKLGADERSGGIILEVDGISDGARFHDVTFGLRKGEILGIGGLIGSGRTEIAEGICGLRPRTAGTVRLHGAAQPIRAYSDAVKAGIVYLSEDRKGSGIFLEMSIAQNISVLDLKALTNAVGLLNGRAEAALADDFARRLAVRMSGIEAPVKSLSGGNQQKVAIAKQLAVKPKVILMDEPTRGIDVGAKAEIHRVLRELASAGIGIIVISSEMPELLGLSDRLLVVREGRIAGELSADEMSEEAVIRLASGMGSARAADHAA
What is the function of this protein?
Part of the ABC transporter complex RbsABC involved in ribose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Ribose import ATP-binding protein RbsA 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS4_CUPPJ
Sequence: MARYTGPKAKLSRREGTDLFLKSARRSLADKCKLDSKPGQHGRTSGARTSDYGNQLREKQKVKRIYGVLERQFRRYFAEADRRKGNTGEKLLQLLESRLDNVVYRMGFGSTRAEARQLVSHKAILVNGQTLNVPSAQIKSGDVITIREQSKKQVRIAEALSLAEQSGFPTWVAVDAKKFEGTFKQVPDRADISGDINESLIVELYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: HUTU_VIBCM
Sequence: MTQSSAQGTRLDTQRTIRAPRGTQLRAKSWLTEAPLRMLMNNLDPDVAEHPHALVVYGGIGRAARNWECFDKIVEVLERLEDDQTLLVQSGKPVGVFPTHKNAPRVLIANSNLVPHWANWEHFNELDKQGLMMYGQMTAGSWIYIGSQGIVQGTYETFVAVAKKHFNGDAKGRWVLTGGLGGMGGAQPLAATMAGFSMIAVECDESRIDYRLRTGYVDKKANTLDEALAMIADTDRPISVGLLGNAADIFPELVKRNITPDVVTDQTSAHDPLNGYLPLGWSMEKAAQMRQQNEAEVVKAAKASMAIQVRAMLDLQTRGAATLDYGNNIRQMALEEGVANAFDFPGFVPAYIRPLFCEGIGPFRWAALSGDPEDIYKTDQKVKELIPDNPHLHNWLDMARERIHFQGLPARICWVGLKDRARLGLAFNEMVKNGELKAPIVIGRDHLDSGSVASPNRETEGMLDGSDAVSDWPLLNALLNTAGGATWVSLHHGGGVGMGFSQHSGMVICCDGSDDAAERIARVLHNDPATGVMRHADAGYEIAKRCAQQQKLDLPMLNAELAKLK
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABH_CHRVO
Sequence: MGYSRILGTGSFLPSQVLTNAQLAERVETSDEWIVSRTGIRARHIADEGHKTSDLALRAAQAAIASAGIDKGEIDLIIVATTTPDMVFPSTACILQEKLGLPGVQAFDVQAVCAGFVYALTTANAYIKSGLAKKALVVGAEIMSRVLDWDDRRTCVLFGDGAGAVVLGESDEPGILHAKLAADGRYQGLLNTPAQISGGKIQGIPYLHMDGPAVFKFAVKSLSEIATATLAEAGVEQASLDWLVPHQANLRIIESTAKHLGLPMDKVVVTLPEQGNTSAASIPLALDVAVRDGRIRRGQTVMLEGIGGGFAWGAVLLTF
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSA_METVS
Sequence: MQQMVPASGYDRAITIFSPEGRLYQVEYAREAVRRGTTAVGIKCKDGVVLAVDRRITSKLIDVSSIEKIFQIDDHIVAATSGLVADARVLIDRARVEAQVNRISYGEAITVEALAKKICDIKQAYTHHGGARPFGLALLITGIDRHSARLFETDPSGALIEYKATAIGSGRPVAMEILEEKYDENMSVSEGMELAIYALSKTTEELKPENIDMAIVKDTGKLVEKITVFEIEKIVKKVYDKIKVENEEAEKKKATENIE
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit alpha, 20S proteasome alpha subunit, Proteasome core protein PsmA.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HYOU1_HUMAN
Sequence: MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAVYQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRKVITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIKAHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDKSEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSVQKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAASTWLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGARLIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDREVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKVETGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
What is the function of this protein?
Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation.  May play a role as a molecular chaperone and participate in protein folding.
What are the official names of this protein?
Hypoxia up-regulated protein 1, 150 kDa oxygen-regulated protein, ORP-150, 170 kDa glucose-regulated protein, GRP-170.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: PYRB_MARN8
Sequence: MTANDPSPNHLQLTRDGQLRHFLTLDGLGQPLLTDILDTADSFIEVGERSIKKVPLLRGRTVVNLFFESSTRTRSTFELAAKRLSADVLNLDISTSATSKGESLSDTLLNLEAMASDMFVVRHSQSGAPHFIAESVTPGVAIINAGDGRHAHPTQAMLDMLTIRQHKGRFEGLKVAIVGDVLHSRVARSQIRALNVLGAEEVRVIAPGTLLPRDVEDLGCTVEYDMARGMKDLDVVIMLRLQKERMEGALLPSEREFYRLYGLNQEKLGLAKPDCIVMHPGPINRGVEIESAVADGPQSVILNQVTNGIAIRMAVMSMAMGGQMAERQQRQQEGRA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: RS27_PONAB
Sequence: MPLAKDPLHPSPEEEKRKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  Required for proper rRNA processing and maturation of 18S rRNAs.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
40S ribosomal protein S27.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS27 family.
Protein: RBL_GRATL
Sequence: MSQSVEERTRIKNQRYESGVIPYAKMGYWDPNYVVKETDVLALFRVTPQPGVDPVEASAAVAGESSTATWTVVWTDLLTACDLYRAKAYKVDAVPNTTDQYFAFIAYDIDLFEEGSIANLTASIIGNVFGFKAVKALRLEDMRIPVAYLKTFQGPATGLIVERERMDKFGRPFLGATVKPKLGLSGKNYGRVVYEGLKGGLDFLKDDENINSQPFMRWKERFLYSMEAVNRAIAATGETKGHYMNVTAATMEEMYERAEFAKQLGSIIIMIDLVIGYTAIQTMAIWARKNDMILHLHRAGNSTYSRQKIHGMNFRVICKWMRMSGVDHIHAGTVVGKLEGDPLMIRGFYNTLLQTHLEVNLPQGIFFEQDWASLRKVTPVASGGIHCGQMHQLLDYLGNDVVLQFGGGTIGHPDGIQAGATANRVALEAMVLARNEGRDYVAEGPQILRDAAKTCGPLQTALDLWKDITFNYTSTDTADFVETPTANV
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NSE5_YEAST
Sequence: MDGALINSVLYVSPRNGAHYFVELTEKHLLAFEMLNSMCLLENYDHVLLFLECQFGKSHNLAVIPFDIILVLFTLSTLSEYYKEPILRANDPYNTSRETLSRRALKLLQKYLAILKEFDSEQYNLYDLELLRCQFFLAIDTLTPKKQKWGFDRFRRTKSESGVTYRQNASVDPELDQAKTFKNPYRSYISCLEQRNTILGNRLLNLKLNEPGEFINMILWTLSNSLQESTPLFLSSHEIWMPLLEILIDLFSCRQDYFIQHEVAQNVSKSLFVQRLSESPLAVFFESLNTRNFANRFSEYVFLNCDYKLPSDNYATPVHPVYNGENTIVDTYIPTIKCSPLYKSQKSLALRRKLIGSCFKLLLRVPDGHRLITPRIVADDVIQGISRTLASFNDILQFKKFFMTENLSQESYFIPLLAEGTLSEILKDTQECVVILTLVENLSDGVSFCNEVIGLVKSKCFAFTEQCSQASYEEAVLNIEKCDVCLLVLLRYLLHLIGTEAILDAKEQLEMLHAIEKNDSGRRQWAKALNLGNDPPLLYPIVSQMFGVHDKSVIIE
What is the function of this protein?
Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage.  Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks.
What are the official names of this protein?
Non-structural maintenance of chromosome element 5, Non-SMC element 5.
What are the subcellular locations of this protein?
Nucleus. Chromosome.