PharMolix/UniProtQA huggingface dataset:
Protein: GG2_ORYSJ
Sequence: MRGEANGEEEQQPPRRNHLRDDAEEEEEVERRAARPVSGQQQQQQRRRPTDVGGGAAMRSVGYVGKHRLSAAIARLDQELQSLQDELNELETMEPASAACQGVITSTEGKSDPLLPVTIGPENASWERWFQRVRSSRSNKWWASKGSDFS
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
What are the official names of this protein?
Guanine nucleotide-binding protein subunit gamma 2, Ggamma-subunit 2, Heterotrimeric G protein gamma-subunit 2.
What are the subcellular locations of this protein?
Cell membrane.
Protein: RHTB_SHIFL
Sequence: MTLEWWFAYLLTSIILSLSPGSGAINTMTTSLNHGYRGAVASIAGLQTGLAIHIVLVGVGLGTLFSRSVIAFEVLKWAGAAYLIWLGIQQWRAAGAIDLKSLASTQSRRHLFQRAVFVNLTNPKSIVFLAALFPQFIMPQQPQLMQYIVLGVTTIVVDIIVMIGYATLAQRIALWIKGPKQMKALNKIFGSLFMLVGALLASARHA
What is the function of this protein?
Conducts the efflux of homoserine and homoserine lactone.
What are the official names of this protein?
Homoserine/homoserine lactone efflux protein.
What is the protein family that this protein belongs to?
Belongs to the Rht family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RUVB_BURM7
Sequence: MIETDKLAAERIIAATPASSHEEAFERALRPRQLDEYVGQEKVRDQLEIFIEAAKRRSEALDHVLLFGPPGLGKTTLAHIIAREMGVNLRQTSGPVLERAGDLAALLTNLEANDVLFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSVKLDLQPFTLVGATTRAGMLTNPLRDRFGIVARLEFYDAEQLSRIVRRSAALLNAQIDPAGALEIAKRSRGTPRIANRLLRRVRDYAEVKADGNITAAVADAALAMLDVDPVGFDLMDRKLLEAILHKFDGGPVGVDNLAAAIGEERDTIEDVLEPYLIQQGFLQRTPRGRVATLLTYRHFGLSAPDAANPVRNLWDTPDAEC
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: MURJ_BUCBP
Sequence: MNILKSLISLSLITFISRILGFMRDLLIAYSFGASGITDAFFLAFKIPNLFRRIFAEGAFSQVFIPILSEYKNNKNIELTRNFISNILGLMIIILSLFTAFGIYFANDIVKICAPGFINSHEKLYLATKMLKIMFPYIFFVSLGSLTGSILNAWNYFSVPAYSSIFLNLSMIMFISFVTAYFNPKILSLAWAVIVGGVFQILYQFPYLKNINMLIFPKFNILNLGVLKFLKQIGIVALGMSVNQVSIIIATISSSFLISGSISWIYYSDRLVEFISGIFGVSLSTILLPLLSKSVNNINIKEYSRLLNWALRLVCILVIPSIIILFTLSESLITLLFKYGAFTYNDVIMTKNVIEFYSIGLLPFVLIKILLAGFYSIRNVKTPMKISIFILVLTQLMNIFFIKYFQYTSFALAISLASWINFFLLYRKLCQSEFFIPSTNWLRFLLKIFAAAMVMLILLFINKNLILSANTHSIFFKILRLFYICASSGGGYLFTLFCLGLRFNHFYLKSYKY
What is the function of this protein?
Involved in peptidoglycan biosynthesis.  Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
What are the official names of this protein?
Probable lipid II flippase MurJ.
What is the protein family that this protein belongs to?
Belongs to the MurJ/MviN family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y9E0_ENCCU
Sequence: MVATNDSEAPQKILYESLCTVEAENLSEACNNAIEGRRAPAGRKAQVMRFIGEMCCCGDMFGTDTSINESVFSAMTYIEKNAWNVKDVFISPESEENVSNCVKLLELNEKIDYSAVHLKDIAMGLRIYVEQNMRNIIPLNVRKRVIEAYGSNDGEMKETIIPRIPFVVGDPHRLFLKSLKNIFLTIEMNAEDNGVNVEEIYRIFGPLVIRRPENMLETDTEVLRQILVDLMKADFDEFPSSFYL
What are the official names of this protein?
Uncharacterized protein ECU09_1400.
Protein: HPE_HAEIN
Sequence: MKKIILTLSLGLLTACSAQIQKAEQNDVKLAPPTDVRSGYIRLVKNVNYYIDSESIWVDNQEPQIVHFDAVVNLDRGLYVYPEPKRYARSVRQYKILNCANYHLTQIRTDFYDEFWGQGLRAAPKKQKKHTLSLTPDTTLYNAAQIICANYGKAFSVDKK
What is the function of this protein?
Acts as a multifunctional adhesin involved in direct interactions with host epithelial cells and host proteins.
What are the official names of this protein?
Surface-adhesin protein E.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Cell surface.
Protein: GLYA_SALHS
Sequence: MLKREMNIADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGGCEYVDVVEQLAIDRAKELFGADYANVQPHSGSQANFAVYTALLQPGDTVLGMNLAQGGHLTHGSPVNFSGKLYNIVPYGIDESGKIDYDEMAKLAKEHKPKMIIGGFSAYSGVVDWAKMREIADSIGAYLFVDMAHVAGLIAAGVYPNPVPHAHVVTTTTHKTLAGPRGGLILAKGGDEELYKKLNSAVFPSAQGGPLMHVIAGKAVALKEAMEPEFKVYQQQVAKNAKAMVEVFLNRGYKVVSGGTENHLFLLDLVDKNLTGKEADAALGRANITVNKNSVPNDPKSPFVTSGIRIGSPAVTRRGFKEAEVKELAGWMCDVLDNINDEATIERVKAKVLDICARFPVYA
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOBA_PSEPK
Sequence: MPDALPPCSILILAGGRGQRMGGRDKGLVDWQGEPLIAHVHRAVRPLSDDLVISCNRNQAAYQAYADRLVGDAEADFPGPLAGVIAGLRVARHAWVVVLACDAPLVDRELIEGLLRLAVAGNSAAMVRQGGFWQPMFSVLPKRVLPVLEQAWAAGERSLQKALLREAVQGLECAESDRRLSNFNSPERLQD
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTC27_CHICK
Sequence: MLALERSLLRGFLSAAESQEWKQGEISATESGSVLQLIFDGKYEAIFSNSTIRNVFSASSVAEEDIESYLEKQILMYLDCSTEVDNMERQRLMFLLGVGSLQLFVQSNWTGPPVHLQLQGFLPSALLQKCLEPKMLHATILKMLVLDAESVYTLTSHPILLLIARVVLVNSRHKLSSLQTLPWWTLRCVNIHQQLLEERSPELFTLAQMCIRQMTEAEALFAGDEGWHLAVQFNLECAYTFLYYYEYKKAKQCFCTAKDIAKLQINLTGALGKRTRFQEKYVAQLILDVQRSEEFIPPHSELTPAPTPLENLTMNCDLNDDTVLNEIKLADADQYQVPDLCAEELAVILGICIDFQKNNPIHKLTEEELLAFTSCLLSQPKFWAIQTSALLLRTKLEKGSTRRMERAMKQTQALADQFEDVNTSVSERMKIFYCCQVPPHWAIQRQLASLLFELGCTSSALQIYEELEMWEDAVICYERAGQHGKAEEILRRELEKKETPVLYCLLGDVLKDHQCYDKAWELSRHRSARAQRSKGLLHLRNREFRECVECFERSVQINPMQLGVWFSLGCAYIALEGYEGAAKAFQRCVTLEPDNAEAWNNLSTAYIRLKQKIKAFRTLQEALKCNYEHWQIWENYLLTSTDVGEFSEAIKAYHRLMDLREKYKDTQVLAILVRAVVDGMADRTGEAASGLKGKLRELLGRVTSRVTNDGEIWRLYARLYGNGHSDSSEDIEKSLQCLTKAHKCEIQSNDWEKDVSSFKEVAKGAIEIAHVAIKCSKKKSNNQEALQILSSARLNLRGLSSKAKQRFVDVGSHEICNEVTDEVTTMDNLIAELQELSNQLRDQG
What are the official names of this protein?
Tetratricopeptide repeat protein 27, TPR repeat protein 27.
What is the protein family that this protein belongs to?
Belongs to the TTC27 family.
Protein: QUEC_HELPY
Sequence: MEQKICVIGFSGGQDSTTLAVWAKKRFKKVCLVGFDYAQKHSVELECAQKIASLLQLPYEIIPLDFLENITRSALFKNSNDLIGHSHAQNKDLPNSFVPNRNAIFITLLHSYAQKLGASNIALGVSQADFSGYPDCKEDFIKSIEHALNLGSNTAIKILTPLMFLNKAQEFQMAKDLGVLDLVIKETHTCYQGERKILHAYGYGCDKCPACQLRKKGFEEFQANKK
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: IF2_PSEF5
Sequence: MTQVTVKQLADEVKTPVERLLQQMREAGLPHTAAEEHVSDSEKQSLLTHLKSSHKAKVEEPRKITLQRKTTSTLRVAGSKSISVEVRKKKVFVQRSPEEIEAERQRELEERRAVENAARQKAEEEAKRRAEEEARRQPAPVAEPVAAQAAAPAPAPVVEPVQEAPVATAAPAADARKKDEQRRPDKTRNDDNRRGGDGERKNAPHRASVKEKAPAPRVAPRTTDEESDGFRRGGRGKAKLKKRNAHGFQSPTGPVVRDVQIGETITVGELAQQMSVKAAEVIKFMFKLGTPATINQVLDQETAQLVAEELGHKVTLVSDTALEDSLAESLKFEGEAVARAPVVTVMGHVDHGKTSLLDYIRRAKVAAGEAGGITQHIGAYHVETERGMVTFLDTPGHAAFTAMRARGAKATDIVILVVAADDGVMPQTVEAVQHAQAAGVPLVVAVNKIDKPGADLDRIRSELSVHGVTSEDWGGDTPFVPVSAKMGTGVDDLLEAVLLQAEVLELKATPSAPGRGVVVESRLDKGRGPVATVLVQDGTLRQGDMVLVGSNYGRVRAMLDENGKPIKEAGPSIPVEILGLDGTPDAGDEMSVVADEKKAREVALFRQGKFREVKLARAHAGKLENIFESMGQEEKKTLNIVLKSDVRGSLEALQGALNGLGNDEVQVRVVGGGVGGITESDANLALASNAVLFGFNVRADAGARKIVEQEGLDMRYYNVIYDIIEDVKKALTGMLGSDVRENILGVAEVRDVFRSPKFGAIAGCMVIEGVVHRNRPIRVLREDIVIFEGELESLRRFKDDASEVRAGMECGIGVKSYNDVKVGDKIEVFEKVQVARSL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FCERG_MOUSE
Sequence: MISAVILFLLLLVEQAAALGEPQLCYILDAVLFLYGIVLTLLYCRLKIQVRKAAIASREKADAVYTGLNTRSQETYETLKHEKPPQ
What is the function of this protein?
Adapter protein containing an immunoreceptor tyrosine-based activation motif (ITAM) that transduces activation signals from various immunoreceptors.  As a component of the high-affinity immunoglobulin E (IgE) receptor, mediates allergic inflammatory signaling in mast cells (PubMed:14764707).  As a constitutive component of interleukin-3 receptor complex, selectively mediates interleukin 4/IL4 production by basophils, priming T-cells toward effector T-helper 2 subset (PubMed:19098920).  Associates with pattern recognition receptors CLEC4D and CLEC4E to form a functional signaling complex in myeloid cells.  Binding of mycobacterial trehalose 6,6'-dimycolate (TDM) to this receptor complex leads to phosphorylation of ITAM, triggering activation of SYK, CARD9 and NF-kappa-B, consequently driving maturation of antigen-presenting cells and shaping antigen-specific priming of T-cells toward effector T-helper 1 and T-helper 17 cell subtypes (PubMed:23602766) (Probable).  May function cooperatively with other activating receptors.  Functionally linked to integrin beta-2/ITGB2-mediated neutrophil activation (PubMed:17086186).  Also involved in integrin alpha-2/ITGA2-mediated platelet activation (PubMed:9171347).
What are the official names of this protein?
High affinity immunoglobulin epsilon receptor subunit gamma, Fc receptor gamma-chain, FcRgamma, Fc-epsilon RI-gamma, IgE Fc receptor subunit gamma, FceRI gamma.
What is the protein family that this protein belongs to?
Belongs to the CD3Z/FCER1G family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: CNN3_MOUSE
Sequence: MTHFNKGPSYGLSAEVKNKIASKYDQQAEEDLRNWIEEVTGLGIGTNFQLGLKDGIILCELINKLQPGSVKKVNESSLNWPQLENIGNFIKAIQAYGMKPHDIFEANDLFENGNMTQVQTTLVALAGLAKTKGFHTTIDIGVKYAEKQTRRFDEGKLKAGQSVIGLQMGTNKCASQAGMTAYGTRRHLYDPKMQTDKPFDQTTISLQMGTNKGASQAGMLAPGTRRDIYDQKLTLQPVDNSTISLQMGTNKVASQKGMSVYGLGRQVYDPKYCAAPTEPVIHNGSQGTGTNGSEISDSDYQAEYPDEYHGEYPDDYPREYQYGDDQGIDY
What is the function of this protein?
Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction.  It is capable of binding to actin, calmodulin and tropomyosin.  The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (By similarity).
What are the official names of this protein?
Calponin-3, Calponin, acidic isoform.
What is the protein family that this protein belongs to?
Belongs to the calponin family.
Protein: Y3573_ACISJ
Sequence: MPADTAPMNLTHHFLIAMPGVEDASFSRSVVYLCEHSERGALGLIINKPTPISLEGLFEKVDLSLGREDLTLQPVFQGGPVQTERGFVLHEAMRGPQESEDESPYASTMTIPGGLEMTTSKDVLEALAHGAGPRRVLVTLGYSAWGEGQLESELAENSWLTVGADVSVIFETPVQERYDRALGLLGLQSWMLSPEAGHA
What are the official names of this protein?
UPF0301 protein Ajs_3573.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: ANM5_ORYSJ
Sequence: MPLGQRAGDKSESRYCGVEVLDFPAGEELPAVLSHSLSSSFDFLLAPLVDPDYRPTPGSVLPVAASDLVLGPAQWSSHIVGKISEWIDLDAEDEQLRLDSEITLKQEIAWASHLSLQACVLPPPKRSSCANYARVVNHILQGLTNLQLWLRIPLEKSEPMDEDHDGAKDNSDMSDTVDSWEWWNSFRLLCEHSSQLCVALDVLSTLPSMNSLGRWFGEPVRAAILQTNAFLTNARGYPCLSKRHQKLLTGFFNHSVQVIISGRSNHNVSQGGVLSGDENHTEDTAVRHALSPYLDYIAYIYQRMDPLPEQERFEINYRDFLQSPLQPLMDNLEAQTYETFEKDTVKYTQYQRAIAKALVDRVSDDDVSTTKTVLMVVGAGRGPLVRASLQAAEETGRKLKVYAVEKNPNAVITLHSLIKLEGWESLVTIISSDMRCWEAPEKADILVSELLGSFGDNELSPECLDGAQRFLKPDGISIPSSYTSFIEPITASKLHNDIKAHKDIAHFETAYVVKLHRIARLAPTQSVFTFDHPNPSPNASNQRYTKLKFEIPQETGSCLVHGFAGYFDAVLYKDVHLGIEPNTATPNMFSWFPIFFPLRKPIYVPSKTPIEVHFWRCCGATKVWYEWAVTAPSPSPIHNSNGRSYWVGL
What is the function of this protein?
Methylates arginine residues in proteins such as histone H4.
What are the official names of this protein?
Protein arginine N-methyltransferase 5, Shk1 kinase-binding protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G3P_PHYIN
Sequence: MNVAINGFGRIGRLVLRASAKNPLINIVAINDPFVSTTYMEYMLEYDTVHGKFDGSLSHDETHIFVNGKPIRVFNEMNPENIKWGEEQVQYVVESTGAFTTLEKASTHLKNGVEKVVISAPSSDAPMFVMGVNHELYEKNMHVVSNASCTTNCLAPLAKVVNDKFGIKEGLMTTVHAVTATQKTVDGPSKKDWRGGRGACFNIIPSSTGAAKAVGKVIPSLNGKLTGMSFRVPTADVSVVDLTARLVNPASYDEIKAAIKSASENEMKGILGYTEKAVVSSDFIGDSHSSIFDAEAGIALTDDFVKLVSWYDNEWGYSSRVLDLIEHMVKNE
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDHJ_TRACE
Sequence: MQGYLSAWLVKHGLIHRSLGFDYQGIETFQIKSEDWHSIAVILYVYGYNYLRSQCAYDVAPGGLLASVYHLTRIKYGVDQPEEVCIKVFATRRDPRIPSVFCVWKSVDFQERESYDMLGISYDNHPRLKRILMPDSWIGWPLRKDYIAPNFYEIQDAH
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit J, chloroplastic, NAD(P)H dehydrogenase subunit J, NADH-plastoquinone oxidoreductase subunit J.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: RF3_TRIV2
Sequence: MSTEIQTELHQAVELRRNFAIISHPDAGKTTLTEKLLLYGGAIHEAGAVKARRAQRKATSDWMAMEQQRGISITSTVLQFEYQNCQINLLDTPGHQDFSEDTYRTLAAADNAVMLIDVAKGLEPQTRKLFEVCKLRGLPIFTFINKLDRPGREPLELLDEIEQELGLQTYAVNWPIGMGDRFKGVFDRNKQQIHLFERSAHGSKEARDTTVELGDPRIEELLEEDLYYQLKNDLELLEGVGPELDLDLVHQGKMTPVFFGSAMTNFGVELFLKYFLNYALKPGVHISSVGEVAPTYPEFSGFVFKLQANMDPKHRDRVAFIRVCTGKFEKDMTVNHARTGKIVRLSRPQKLFAQERESIDVAYPGDVIGLNNPGVFAIGDTIYTGQKLEYEGIPYFSPELFATLRNPNPSKFKQFQKGISELREEGAVQIMYSVDEAKRDPIMAAVGQLQFEVVQFRLQNEYGVETILELLPYSVARWVDGGWEALNKVGRIFNTTTVKDSMNRPVLLFRNEWNCQQLQGDHPELKLSAIAPVFSSQTVE
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_SHEPC
Sequence: MADTTVEKLATEVGKSVERLIEQFSQAGIKKGQADNVSEAEKQQLLDYLKKQHGADSAPTKMTLQRKTVSTLSVAGNGGQSKDVKVEVRKTRTFVKRDVNDTVLKAEEEAKAEAEALAKAKAEAEAAQAAKAKAEAEAKAKAEAEAKAKAKAAAEVKVTKESSPEVEAARLEAERLKAAQEAATKRKQDEEAAKAAEKARLLAEENSKRWAEEERQRLEAERNGDHHITTSKVARAAEDTSDLDEEKRGRRARNKSNAKKRGGKDARDGREKHMRNRSTAPESMAHGFNKPVAAVSRDVRIGETVTVSELAHLMAVKATEIIKQMMKMGSMVTINQVLDQETAQLVAEEMGHKVVLIRENELEHQVLQDRDDEDGIKLESRAPVVTIMGHVDHGKTSLLDYIRRAKVAAGEAGGITQHIGAYHVETENGMITFLDTPGHAAFTAMRARGAKATDIVVLVVAADDGVMPQTIEAIQHAKAGNVPLIVAVNKMDKPEADIDRVKSELSQHGVMSEDWGGDNMFAFVSAKTGEGVDDLLEGILLQAEVLELKAVRDGMAAGVVIESQLDKGRGPVATILVQEGTLRQGDIVLCGLEYGKIRAMKDENGRSITEAGPSIPVEILGLSGVPSAGDEATVVRDERKAREVALYRQGKFRDVKLARQQKSKLENMFANMTDGEVKELNIVLKADVQGSLEAITDSLTGLSTDEVKVNIIARGVGALTETDATLAAASNAIMVGFNVRADAQARKVIESESVDLRYYSVIYNLIDEVKAAMTGMLSPEFKQQIIGLAEVRDVFKSPKLGAIAGCMVTEGTIKRSAPIRVLRDNVVIFEGELESLRRFKDDVAEVRNGMECGIGVKNYNDVRVGDQIEVFETVEVARTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR14_PORPU
Sequence: MAKKNMIQREIKREKLEKKYYLKRLAIKEQLKKTTSFAEKIELRQKLQEMPRNSAPVRSRNRCWLTGRSRGYYRDFGLSRHVFREMSHECLLPGVTKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SHE3_ZYGRC
Sequence: MTEDFEVNLGTGGEDNSSSTMEHRVLDSPPRVVIPEDTESPAKLAPNHGIFMASINKSSPAGKKSGEGAVLGMGAQSTKDNSTPRQNSSMLSTRVIESLHDQVDTLTSTNLQLTVQSKNLLDKLDTAQQKESKMLENSASLKHENENLVSMLNRKTRRLKDVEEELASHKKNHDSLEEEKTALQKKWESSSSEEATLRQQMEMVQAQYDALVDSHQYYKSHYSSQISTLSEQLENLKLEQRNYTQRVSDEANTFNAKLLEFDSKHANLQQAEETRVKYLESKYDSLTQQLDLPSWVQLYRESKNMVLEFAEKMKLKIPSDFETLIQDPELTALEAKNPNSNNAAALPLRVAKQRAGGGNATSTQSGTSGSNAAHGKRSSFYGGMASSYPASTLPGTLPGVRRSSSRRKPSSRVASDNSNSGDSSPIFPHSAVATAPRSSATAPSSRVSSTSTSSSTNHFAFHNNNSNNTYRKRQESTSVGNS
What is the function of this protein?
RNA-binding protein that binds specific mRNAs including the ASH1 mRNA, coding for a repressor of the HO endonuclease.  Part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud and in the daughter cell.  Required for the delivery of cortical endoplasmic reticulum into the emerging bud (By similarity).
What are the official names of this protein?
SWI5-dependent HO expression protein 3.
What is the protein family that this protein belongs to?
Belongs to the SHE3 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: CUTC_VIBCH
Sequence: MKYQVEVCIDNIESLHNAIAGGATRIELCSSLALGGLTPSAGLMYSAGRVSPIPAYAMIRPREGDFFYHDDELSIMAQDIRTAHQANLQGVVLGLLNADGTIDVKRSKPLIELAHSLGLGVTFHRAFDHCVNPEHALEEIIALGCERILTSGLARNAYLGIERLAQLVKQSAGRISIMAGAGINAQNVAEIALATGVNELHLSAKTTRPSEMLFIRSESKMGAADCDDFIIPVTSRDALQQTVHALAALNSVLH
What are the official names of this protein?
PF03932 family protein CutC.
What is the protein family that this protein belongs to?
Belongs to the CutC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF1A_SULIL
Sequence: MPKKDRAQEAPSRDVPKPEEGQTICVVKKMLGGDHLVVLCMDGKERLARIPGKIRKKMWMREGDVVLVGIWDFQPNRCDILYKYGNDEIKRLVNENIISREVIDQLRG
What is the function of this protein?
Seems to be required for maximal rate of protein biosynthesis.  Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
What are the official names of this protein?
Translation initiation factor 1A, aIF-1A.
What is the protein family that this protein belongs to?
Belongs to the eIF-1A family.
Protein: NRAM_I45A0
Sequence: MNPNQKIITIGSICMVVGIISLILQIGNIISIWISHSIQTGSQNHTGICNQSIITYKNSTWVNQTYVNISNTNVVAGKGTTPVILAGNSSLCPIRGWAIYSKDNGIRIGSKGDVFVIREPFISCSHLECRTFFLTQGALLNDKHSNGTVKDRSPYRALMSCPVGEAPSPYNSRFESVAWSACACHDGMGWLTIGISGPDDEAVAVLKYNGIITETIKSWRKKILRTQESECVCVNGSCFTIMTDGPSDGPASYKIFKIEKGKVTKSIELDAPNSHYEECSCYPDTGKVMCVCRDNWHGSNRPWVSFDQNLDYQIGYICSGVFGDNPRPKDGKGSCGPVYVDGANGVKGFSYRYGNGVWIGRIKSNSSRQGFEMIWDPNGWTETDSSFFVKQDVVAMTDWSGYSGSFVQHPELTGLDCMRPCFWVELIRGRPKEKTIWTSGSSISFCGVNSDTVDWSWPDGAELPFTIDK
What is the function of this protein?
Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates.  Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release.  Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell.  Otherwise, infection would be limited to one round of replication.  Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors.  May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells.  Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport.  May additionally display a raft-association independent effect on budding.  Plays a role in the determination of host range restriction on replication and virulence.  Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
What are the official names of this protein?
Neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 34 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type II membrane protein. Note=Preferentially accumulates at the apical plasma membrane in infected polarized epithelial cells, which is the virus assembly site. Uses lipid rafts for cell surface transport and apical sorting. In the virion, forms a mushroom-shaped spike on the surface of the membrane.