PharMolix/UniProtQA huggingface dataset:
Protein: ODC2_YEAST
Sequence: MSSDSNAKPLPFIYQFISGAVAGISELTVMYPLDVVKTRFQLEVTTPTAAAVGKQVERYNGVIDCLKKIVKKEGFSRLYRGISSPMLMEAPKRATKFACNDQYQKIFKNLFNTNETTQKISIAAGASAGMTEAAVIVPFELIKIRMQDVKSSYLGPMDCLKKTIKNEGIMGLYKGIESTMWRNALWNGGYFGVIYQVRNSMPVAKTKGQKTRNDLIAGAIGGTVGTMLNTPFDVVKSRIQSVDAVSSAVKKYNWCLPSLLVIYREEGFRALYKGFVPKVCRLAPGGSLMLVVFTGMMNFFRDLKYGH
What is the function of this protein?
Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria.  Can transport 2-oxoadipate, 2-oxoglutarate, adipate, glutarate, 2-oxopimelate, oxaloacetate, citrate and malate.  The main physiological role is probably to supply 2-oxoadipate and 2-oxoglutarate from the mitochondrial matrix to the cytosol where they are used in the biosynthesis of lysine and glutamate, respectively, and in lysine catabolism.
What are the official names of this protein?
Mitochondrial 2-oxodicarboxylate carrier 2.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SEC23_PHANO
Sequence: MADFEAMKDTWSDVEDRDGVRLSWNTFPSSRMEASRLVVPIGALYTPLKEKTDTPLLQYEPVVCRAPCKGVLNPYCQVDMRARVWICPFCLNRNQLPPHYKDISQEQIPPELHPSSTTIEYRLPKPARCAPIFIFVIDTCQEEDSLKALKDSIIMSLSLLPAYALVGLITYGTMTQVHELGYTECAKSYVFRGNKDYSTKQVQTMIGLGQMAAPRPGMQAQPGQPGGAPPTAAMRFILPVGQCEFQLTNVLESLQRDPWPVANDKRALRCTGVALSVASGLLEASNFVNTGARIMLFAGGPATEGPGMVVGPELREPIRSHHDIDRDNIKYYKKALKFYETLAKRVSTNGHIVDIFAGCLDQVGLLEMRGLANTTGGHMILTDSFTSSMYKQSFARVFNKDADDNLLMGFNAEMEVLTTKELKVTGLIGHAVSLNKKSVNVGETECGIGNTCAWKMCGIDPEASYGIYFEIAGQGGPSGMTGGAPQAIMQFLTYYQHSSGQMHLRVTTVSRPMSGPSGDPALAQSFDQEAAAVLMSRIAVFKAEVDDGPDVLRWVDRMLIRLCSRFAEYRKDDPSSFRLEKNFTLYPQFMFHLRRSQFLQVFNNSPDETAFYRHVLNHEDVGNSLVMIQPTLDSYGFDHEGGQPVLLDSASIQSETVLLLDTFFHILIFHGETMAEWRKAGYQDQEGYENFRTLLEAPKEDAKDLIQDRFPLPRFIVCDAGGSQARFLLSKLNPSTTHQTSTYGGVAQTAQTIFTDDVSLQTFMDHLMKLAVSGTS
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
What are the official names of this protein?
Protein transport protein SEC23.
What is the protein family that this protein belongs to?
Belongs to the SEC23/SEC24 family. SEC23 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: VPR_HV1M2
Sequence: MEQPPEDQGPQREPYNEWTLELLEELKHEAVRHFPREWLHGLGQHIYNTYGDTWEGVEAIIRILQQLLFIHFRIGCHHSRIGIIRQRRIRNGSGRS
What is the function of this protein?
During virus entry, plays a role in the transport of the viral pre-integration (PIC) complex to the host nucleus.  This function is crucial for viral infection of non-dividing macrophages.  May act directly at the nuclear pore complex, by binding nucleoporins phenylalanine-glycine (FG)-repeat regions.
What are the official names of this protein?
Protein Vpr, R ORF protein, Viral protein R.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 VPR protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host extracellular space. Note=Incorporation into virion is dependent on p6 GAG sequences. Lacks a canonical nuclear localization signal, thus import into nucleus may function independently of the human importin pathway. Detected in high quantity in the serum and cerebrospinal fluid of AIDS patient.
Protein: ENOPH_YEAS6
Sequence: MGDNYSTYLLDIEGTVCPISFVKETLFPYFTKKVPQLVQQDTRDSPVSNILSQFHIDDKEQLQAHILELVAKDVKDPILKQLQGYIWAQGYESGQIKAPVYADAIDFIKRKKRVFIYSSGSVKAQKLLFGYVQDPNAPAHDSLDLNSYIDGYFDINTSGKKTETQSYANILRDIGAKASEVLFLSDNPLELDAAAGVGIATGLASRPGNAPVPDGQKYQVYKDFETL
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase, Unknown transcript 4 protein.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DEF3A_RAT
Sequence: MRTLTLLTTLLLLALHTQAESPQGSTKEAPDEEQDISVFFGGDKGTALQDAAVKAGVTCSCRTSSCRFGERLSGACRLNGRIYRLCC
What is the function of this protein?
Active in vitro against S. aureus, fungi, Gram-positive and Gram-negative bacteria and to a lesser extent against an enveloped virus.
What are the official names of this protein?
Neutrophil antibiotic peptide NP-3A, RatNP-3a, Neutrophil defensin 3.
What is the protein family that this protein belongs to?
Belongs to the alpha-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: DCUP_GEODF
Sequence: MNTRFLDACWGKPVDRTPVWLMRQAGRYLPDYMRVRSKCTFLELCKTPELAAEVTIQPVDILGVDAAILFSDILTPVEPMGMALDFVPGPVFEHPIRTMADVEKLRIPQMEQDVPYVLETIKILRRELANKVPLIGFGGAPFTLACYMVEGKGSKDWATIKRMMYAAPEVYAALMEKVTMMDMEYLNAQIKAGAQAIQIFDTWGGVLSPSDYEKFVLPYTTKLINGLNRQNVPVIHFVKGAGTMLDTVKKAGGDVMGLDWHTNLGKARDILGSMAVQGNLDPTVLFAPNDVIEKEVKRVLDENGGRSGHIFNLGHGILPTVPPENAIHMVECVHRLSQQ
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEM6D_MOUSE
Sequence: MGFLLLWFCVLFLLVSRLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQHRLDFQLMLKIRDTLYIAGRDQVYTVNLNEIPQTEVIPSKKLTWRSRQQDRENCAMKGKHKDECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLRTLEYDGEEISGLARCPFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDDTLAFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAIEVDRSAGPYQNYTVIFVGSEAGVVLKVLAKTSPFSLNDSVLLEEIEAYNPAKCSAESEEDRKVVSLQLDKDHHALYVAFSSCVVRIPLSRCERYGSCKKSCIASRDPYCGWLSQGVCERVTLGMLPGGYEQDTEYGNTAHLGDCHESLPPSTTPDYKIFGGPTSDMEVSSSSVTTVASSPEITSKVIDTWRPKLTSSRKFVVQDDPNTSDFTDTISGIPKGVRWEVQSGESNQMVHMNVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKIHKDAESAQSCTDSSGSFAKLNGLFDSPVKEYQQNIDSPKLYSNLLTSRKELPPNTDTKSMAVDHRGQPPELAALPTPESTPVLHQKTLQAMKSHSEKAHSHGASRKEHPQFFPSSPPPHSPLSHGHIPSAIVLPNATHDYNTSFSNSNAHKAEKKLQSMDHPLTKSSSKREHRRSVDSRNTLNDLLKHLNDPNSNPKAILGEIHMAHQTLMLDPVGPMAEVPPKVPNREASLYSPPSTLPRNSPTKRVDVPTTPGVPMTSLERQRGYHKNSSQRHSISAVPKNLNSPNGVLLSRQPSMNRGGYMPTPTGAKVDYIQGTPVSVHLQPSLSRQSSYTSNGTLPRTGLKRTPSLKPDVPPKPSFVPQTTSVRPLNKYTY
What is the function of this protein?
Shows growth cone collapsing activity on dorsal root ganglion (DRG) neurons in vitro.  May be a stop signal for the DRG neurons in their target areas, and possibly also for other neurons.  May also be involved in the maintenance and remodeling of neuronal connections (By similarity).
What are the official names of this protein?
Semaphorin-6D.
What is the protein family that this protein belongs to?
Belongs to the semaphorin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: GPR78_HUMAN
Sequence: MGPGEALLAGLLVMVLAVALLSNALVLLCCAYSAELRTRASGVLLVNLSLGHLLLAALDMPFTLLGVMRGRTPSAPGACQVIGFLDTFLASNAALSVAALSADQWLAVGFPLRYAGRLRPRYAGLLLGCAWGQSLAFSGAALGCSWLGYSSAFASCSLRLPPEPERPRFAAFTATLHAVGFVLPLAVLCLTSLQVHRVARRHCQRMDTVTMKALALLADLHPSVRQRCLIQQKRRRHRATRKIGIAIATFLICFAPYVMTRLAELVPFVTVNAQWGILSKCLTYSKAVADPFTYSLLRRPFRQVLAGMVHRLLKRTPRPASTHDSSLDVAGMVHQLLKRTPRPASTHNGSVDTENDSCLQQTH
What is the function of this protein?
Orphan receptor.  Displays a significant level of constitutive activity.  Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP.
What are the official names of this protein?
G-protein coupled receptor 78.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DER_ALBFT
Sequence: MKPVVALVGRPNVGKSTLFNRLTKSRDAIVADFAGLTRDRHYGNAKQGKHEFIVIDTGGFEPDAAGGIFKEMAKQTTQAVAEADVVIFVVDAREGISAQDHEIAKYLRRLGKPCVLAANKAEGMLAGAQLVEFFELGLGEVHAISAAHGQGIRTLVDLALAPLHLEDQDDADEQREPGIIKLAVAGRPNVGKSTLINTWLGEERLVAFDLPGTTRDAISVPFERNGQKFELVDTAGLRRRGKVFEAIEKFSVVKTLQAIESSNVVLLLIDATQGVTDQDAHIAGYILENGRAVVIAVNKWDAVDEYQRELVKRSIETRLPFLKFATMHLISATKRQGLGPLWASIAQAYKAANCKMSTPILTRLLLEAVQFQSPKRSGMFRPKLRYAHQGGMNPPVIIIHGNSLEHVTDAYKRFLEGRFRKEFDLVGTPMRIEFKSSTNPYADKATA
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: RPIA_BACCR
Sequence: MNLKQLAGEYAANFVNDGMKIGLGTGSTVYWTIQKLGERVKEGLSFQAVPTSKETEALAQQLNIPLISLNDVQSLDLTIDGADEIDSNLQLIKGGGGALLREKIVASSSKKLIIIADESKLVTHLGTFPLPIEIIPFSWKQTENKIQSLGCQTTLRLKNNETYITDNNNMIIDCIFPNHISNPVHLHTQLKMITGVVETGLFISMTSTAIIGTKNGIKKL
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: RBR2_MAIZE
Sequence: MSSQDPPPATSTQKKQSESLVNLLAEASRFYRKAYNELFSGLITEWEPESSTNIPDYMLFGWHLFLNLRLRSPELFKDLVSCIHGLVAVLAILLVHVPAKFRTFTIEGSSHLIKQTEKGVDLIASLCHNYHTSEECLKEMMDKSHKAIEEVFSMKALSASECKTENLDKIDTDRLMYFKGLIDMECFQSNLEKIEKLCNSNNCEAELDFKLILTNNDYIPCAENLSRDSTNLGCSKCAFETLASPRKTIKNMLTVPSSPLSPTNGCSVKIVQMTPITSAMTTAKWLREVISSLPEKPSSKLQQLMSSCDRDLTYAVTERVSIVLEAIFPTKSSADRGGSLGLNCANAFDTLWADARKMEASKLYYRVLEAICRAELQNSNVNNLTPLLSNERFHRCLIACSADVVLATHKTVIMMFPAVLESAGLTSFDLSKIIENFVRHEETLPRELKRHLNSLEEQILESMAWEKGSSLYNSLIVARPSVASEINRFGLLAESMPSLDDLVARQNIHIEGLPATPSKKRAAGRDDNADPRSPKRPCNESRSPVVEHNLQTPPPKQCHMVLTSLKAKCHPLQSTFASPTVSNPVGGNEKCADVTIQIFFSKILKLAAIRIRNLCERIQYMEQTERVYNVFKQILDQQTTLFFNRHIDQLILCCLYGVAKVCQLELSFREILNNYKKEAQCKPEVFLSIYIGSRNHNGVLISRHVDIITFYNEVFVPAAKPFLVSLISSGTRPEDKKNASGQVPGSPKLSPFPNLPDMSPKKVSASHNVYVSPLRQTKMDLLLSPSSRSFYACIGEGTHAYQSPSKDLAAINSRLNYNGRRVNSRLNFDMVSDSVVAGSLGQPNGGSTSLDPAAAFSPLSKRKPDT
What is the function of this protein?
Regulator of biological processes that recruits a histone deacetylase to control gene transcription.  May play a role in the entry into mitosis, negatively regulating the cell proliferation.  Formation of stable complexes with geminiviridae replication-associated proteins may create a cellular environment which favors viral DNA replication (By similarity).
What are the official names of this protein?
Retinoblastoma-related protein 2, ZmRBR2.
What is the protein family that this protein belongs to?
Belongs to the retinoblastoma protein (RB) family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EDA30_ARATH
Sequence: MVFKSRIKWIALFVLILSMGSLVVHLSMTKSSGVQLAYSARDNLWQDFDSLLGAQDFRNKHLWRPVKSLETLQPYANPRNSYPAPSSKNNGFIYAKIFGGFDKIRSSICDLVTISRLLNATLVIPELQESLRSKGISNKFKSFSYLYDEEQFIAFLKNDVIVMKTLPESLKAARKRNEFPLFKPKNSASPKFYLEDVLPKLKKANVIGLIVSDGGCLQSALPASMPELQRLRCRVAFHALQLRPEIQVLAKEMVDRLRKSGQPFLAYHPGLVREKLAYHGCAELFQDIHSELIQYRRAQMIKQRFILEELIVDSRLRRDNGLCPLMPEEVGILLKALGYSQKAIIYLAGSEIFGGQRVLIPLRAMFPNLVDRTSLCSTEELSELVGPETPLPENTYKMPPRKSDKQLKEEWNKAGPRPRPLPPPPDRPIYQHEKEGWYGWLTENDTEPSPSPMDLRNQAHRLLWDALDFAVSVEADVFFPGFNNDGSGWPDFSSLVMGQRLYERPSSRTYRLDRKVIQELFNITREDMYHPNRNWTLRVRKHLNSSLGESGLIRQSMLSKPRSFLSHPLPECSCRTSALEDSRQIQSDDGRFLYGGEDECPKWIKSAGVEKSKTDDGDQPDYDHDLLAEQSETEEEFAKSKVASAFDQDEEWDPND
What are the official names of this protein?
Protein EMBRYO SAC DEVELOPMENT ARREST 30, O-fucosyltransferase 22, O-FucT-22, O-fucosyltransferase family protein, Protein TUBE GROWTH DEFECTIVE 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase GT106 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: FABA_ESCF3
Sequence: MVDKRESYTKEDLLASGRGELFGAKGPQLPAPNMLMMDRVVKMTETGGNYDKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEGKGRALGVGEVKFTGQVLPTAKKVTYRIHFKRIVNRRLIMGLADGEVLVDGRLIYTASDLKVGLFQDTSSF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UL74A_HCMVM
Sequence: MALTRGGDPAPSVCLVVWFACVYSLLILVVLLLIYRCCIGFQDDLVSRTLAVYRACIQGPICNQTHNSTS
What are the official names of this protein?
Uncharacterized protein UL74A.
What are the subcellular locations of this protein?
Virion membrane; Single-pass membrane protein.
Protein: KAE1B_METTH
Sequence: MLCLGIEGTAEKTGVGIVDEAGNVLSLRGKPLIPEKGGIHPREAAEHHAKWIPRLIAEACRDAGVELGEIGLISFSRGPGLGPALRTVATAARTLALSLDVPIVGVNHCIGHIEIGRLTTGASDPVSLYVSGGNTQVIAFNEGRYRVFGETLDIAVGNMLDQFARESGLGHPGGPVIEQLALKASEYIELPYSVKGMDISFSGLLTAALRKMEAGASLEDLAYSIQETAFSMLVEVTERALAYTEKNQVLLCGGVAVNRRLRDMLREMCQEHHVEFHMPPPEYCGDNGAMIAWLGQLVYKYRGPDALEDTTVVQRYRTDEVDVPWMRESEAGIELPPDILAKGAEANIYRGQWIGRPCIIKERISKGYRIPEIDQKLRSSRTRREARLINQAKGAGVHTPVLFDVDPDGGVMVMEEVRGTPFRDAVEDTELCSRIGEAIGRLHHAGIIHGDLTGSNIIIRGGDVVFIDFGLGRFSDEIEDMGVDLLVLKKSLESTHYALAGECFSRVLEGYGKIIDADIQSKIREIESRGRYTD
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.  The Kae1 domain likely plays a direct catalytic role in this reaction.  The Bud32 domain probably displays kinase activity that regulates Kae1 function.
What are the official names of this protein?
Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the protein kinase superfamily. Tyr protein kinase family. BUD32 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF1_CAUVC
Sequence: MAKEELLEFPGTVSELLPNATFRVKLENDHEIIAHTAGKMRKNRIRVLAGDKVLVEMTPYDLTKGRITYRFK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAS1_MYCTU
Sequence: MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRERDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIRAHTSGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWRAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGDPHRYTFQYALDLQLQSLVRVIEAGHPSRLVDIDITSEPSGA
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  The type III-A Csm effector complex binds crRNA and acts as a crRNA-guided RNase, DNase and cyclic oligoadenylate synthase; binding of target RNA cognate to the crRNA is required for all activities (Probable).  This CRISPR-Cas system protects bacteria against transformation with plasmids containing DNA homologous to its spacer regions (PubMed:29979631).
What are the official names of this protein?
CRISPR-associated endonuclease Cas1.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endonuclease Cas1 family.
Protein: PYRD_VIBA3
Sequence: MLYRLARTGFFQLDAEKAHDLAIQNFKRFTGTPIDLLYRQQLPNRPVECMGLTFKNPVGLAAGLDKNGECIDAFGAMGFGFVEVGTVTPRPQAGNDKPRLFRLVEAEGIINRMGFNNLGVDNLIENVKKSNYDGILGINIGKNKDTPIEKGAEDYLICMEKVYQYAGYIAVNISSPNTPGLRSLQYGEALDDLLSELKTKQSELEEKHGKYVPLALKIAPDLSDDEISQICESLIKNKIDGVIATNTTLDRSIVEGMKHCDEAGGLSGRPVQSRSTEVVRKLHEELGDALPIIGVGGVDSYVAAKEKMMAGAKLVQVYSGFIYKGPGLVGDIVKNL
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: VATB1_CLOTE
Sequence: MLKEYRTVKEVVGPLMLVDGVENVKFDELVEIEIQTGEIRRGRVLEINEDKALVQLFEGSAGINIKGSKAKFLGKPLEISVSEDMLGRVFDGLGRPKDEGPRIIPEKRLDINGIPINPVARNYPSEFIQTGISAIDGLNTLVRGQKLPVFSGSGLPHAQLAAQIARQAKVLNSDSKFAVVFAAVGITFEEAEFFVDDFTKTGAIDRSVLFMNLANDPAIERIATPRMALTTAEYLAFEKGMHVLVILTDLTNYCEALREVSAARKEVPGRRGYPGYLYTDLATLYERAGRIKGKEGSITQIPILTMPEDDKTHPIPDLTGYITEGQIILSRELYRKGVMPPIDVLPSLSRLKDKGIGEGKTREDHADTMNQLFAGYAQGKEAKELAVILGESALSDVDKQYAKFGDAFEKQYVSQGFTTNRTIEETLNLGWELLSILPRTELKRIRDAYLEKYLPKEKSKE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type beta chain is a regulatory subunit.
What are the official names of this protein?
V-type ATP synthase beta chain 1, V-ATPase subunit B 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: CP096_HUMAN
Sequence: MSFSLTFTELANIAIPQCGVLNFKALHLLLHGILEHIHMAELKKVLSGDEDFLQTSQVVIMPREGDAQPILNPMKRLSNVFDHVVSRLDKLENQLALLQDLPSTAQLLEASQGTARPVQDLWHLIKLRKMVEGHDEVMAKSMQTLQDLLTDLHALQVTITALRKEVDMLKNMLDKVHPERMDIFAEDFKIQNWKMVALQREVASLQNKFKTIPKTEDMVLWSGLHDAMFTSEIGSSPLDLWQSVEQLPEAALAQTTKYLEATRAIQVSEPVQNPQLLQTVWHYEVPELLPEGSSAQAVSLSRAQEPAQPPALTPESAPGCTTEFAPGPAPGTEPVPGLELGLELEPVPALGPVPGPSVTPGSLPAPWPVLGPVPAPGAQPPPLGDWPALPRRWPLPQGWPRVGSWPLWDLGVLRPTQPQPSRAPPPATEFGSLWPRPLQPYQSRQGEALQLAAVQVKGEENDVPSLRGLRERARKDGAPKDRTRKDGVPKDRGGKDVDPKDRAHKDDVPKDRGGKDVDPKDRAHKDDVPKDRGGKDGDPKDRVGKDGAPKEAQPKAPQSALHRLKTTAAIAAAAAAAYAAATSSAAQAAKVAAKFVKDAPATKMAAIATDTAAAGPLGVFADVLGAGPSRGATESQILGDDSEIYEILSPSYSAASIGPDPALSQAMVATKQAMSPEDKKRAVKYSMSHIAQIPVKHDSLKEEFAQLSCNLNQRLSYLANMGGPSSLGTTVDILQKKIGSLQKSRLKEEELERIWGNQIEMMKDRYITLDKAVENLQIRMDEFKTLQAQIKRLEMNKVNKSTMEEELREKADRSALAGKASRVDLETVALELNEMIQGILFKVTIHEDSWKKAMEELSKDVNTKLVHSDLDPLKKEMEEVWKIVRKLLIEGLRLDPDSAAGFRRKLFKRVKCISCDRPVEMMTGPQLITIRKAHLLSRLRPASANSCEYLQRQQMREQQWLQLQDLGIQEDCQQDWGDGPQNATSLKCKSCNLLTLYPYGDPHVIDYDSAEVDILGVDGILYKGRVNSQRGAQPLAVAKELAAVKAPSPPSQSLYDRVHSSALFGAICPPLCPRSSACSAASGPHLTMPARPPSLPPLLLLPPLIPSLRDPQQAPGSTRLSRAPHIESRVGRKPPEEPANP
What are the official names of this protein?
Uncharacterized protein C16orf96.
Protein: RL1_HERAR
Sequence: MAKLSKRVKAFKAKVDRTKAYPFDNALALIKECASAKFNESIDVSVQLGVDAKKSDQVVRGSVVLPAGTGKDVRVAVFATGEKAEQAKAAGADIVGMEDLAESIKAGNMPFDIVIASPDTMRIVGTLGQILGPRGMMPNPKVGTVTPDVATAVKNAKAGQVQYRTDKAGIIHATIGRKSFTDEALKSNLLALIDALTKAKPATSKGVYLRKVSLSSTMGAGVRIDQTTLAA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: MYB_HUMAN
Sequence: MARRPRHSIYSSDEDDEDFEMCDHDYDGLLPKSGKRHLGKTRWTREEDEKLKKLVEQNGTDDWKVIANYLPNRTDVQCQHRWQKVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHLNPEVKKTSWTEEEDRIIYQAHKRLGNRWAEIAKLLPGRTDNAIKNHWNSTMRRKVEQEGYLQESSKASQPAVATSFQKNSHLMGFAQAPPTAQLPATGQPTVNNDYSYYHISEAQNVSSHVPYPVALHVNIVNVPQPAAAAIQRHYNDEDPEKEKRIKELELLLMSTENELKGQQVLPTQNHTCSYPGWHSTTIADHTRPHGDSAPVSCLGEHHSTPSLPADPGSLPEESASPARCMIVHQGTILDNVKNLLEFAETLQFIDSFLNTSSNHENSDLEMPSLTSTPLIGHKLTVTTPFHRDQTVKTQKENTVFRTPAIKRSILESSPRTPTPFKHALAAQEIKYGPLKMLPQTPSHLVEDLQDVIKQESDESGIVAEFQENGPPLLKKIKQEVESPTDKSGNFFCSHHWEGDSLNTQLFTQTSPVADAPNILTSSVLMAPASEDEDNVLKAFTVPKNRSLASPLQPCSSTWEPASCGKMEEQMTSSSQARKYVNAFSARTLVM
What is the function of this protein?
Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'.  Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.
What are the official names of this protein?
Transcriptional activator Myb, Proto-oncogene c-Myb.
What are the subcellular locations of this protein?
Nucleus.
Protein: DPO4_STRP2
Sequence: MLIFPLLNDLSRKIIHIDMDAFFAAVEIKDNPKLRGKPVIIGSDPRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKAVGLQIRAIFKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKFLAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLEVPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKELTLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSIAQKTQDASQISQIALQLYEELSEKERGVRLLGITMTGF
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSA_ALBFT
Sequence: MKLCGFEVGLNQPLFLIAGPCVIESEQLQMDTAGTLKEITASLGIAFIFKSSFDKANRSSGSTFRGPGIERGLEILAKVKRELGVPILTDIHSEDQIAQVASVVDVLQTPAFLCRQTDFIRAVAQSGLPVNIKKGQFLAPGDMKNVIDKARAAAREKGLNEDNFMACERGVSFGYNNLVSDMRSLAIMRDTGAPVVFDATHSVQLPGGQGTSSGGQREMVPVLARAAVAVGVAGLFMETHPDPSKALSDGPNAVPLKHMRALLETLVALDAVTKKNGFLENSFAA
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.