PharMolix/UniProtQA huggingface dataset:
Protein: ILVD_CORJK
Sequence: MNAIPLRSAVTTQGRNAAGARALWRATGMTDQDFEKPIIAIANSYTQFVPGHVHLKDVGDIVADAIREAGGVPREFNTIAVDDGIAMGHAGMLYSLPSREVISDAVEYMVNGHAADALVCISNCDKITPGMLNAAMRLNIPVVFVSGGPMEAGKAVAVDGVVQAPTDLITAISASASDKVDAQALLEVESAACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSTLATHAKRRDLFTKAGTTIVELCRRYYGEGDASVLPRNIATREAFENAMALDMAMGGSSNTVLHILAAAQEGEIDFDLHSIDQLSREVPCLSKVSPNSDYHMEDVHRGGGIPAILGELYRAGKLNEGVHSVHSATLKEWLLSWDIRSGAATEEAIELFHAAPGGVRTTAPFSTENRWSSLDTDAEGGVIRDVEHAYTADGGLVVLRGNLAEDGAVIKAAGVDPSIWHFEGKALVVESQEEAVRVILDKKVKPGHVVVVRYEGPAGGPGMQEMLHPTAFLKGAGLGKECALITDGRFSGGTSGLSVGHISPEAAHGGLIGLVRDGDPITIDVHERLLQLNISDEEIERRRAEMEASDKPWTPTTRQRKVTKALRAYAAMATSADRGAVREVK
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: RL13_ACIF2
Sequence: MKTYSAKSHEVQGDWFVVDATDKVLGRLSVELAKRLRGKHKPEYTPHADTGDYIVVINADKIAVTGNKAKDKIYYHHTGYVGNLKSASFEKMKETHPERIIELAVKGMLPKNPLGRAMFKKLKVYTGSEHPHSAQQPQPLNV
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RS21_DINSH
Sequence: MQVSVRDNNVDQALRALKKKLQREGVFREMKLKQHYEKPSEKKAREKAEAIRRARKLARKKAQREGGL
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: RL2_LEUCK
Sequence: MAIKKYKPTSNGRRNMTASDFAEITKSTPEKSLLAKKSKTGARNNSGRMTVRHHAGGHKQAYRLVDFKRIKDNTTATVKAIEYDPNRTANIALLVYEDGIKSYILAPKGLKVGDKVQSGPDADIKVGNALPLSNIPEGTLIHNIELKPGKGGQLARSAGTSAQILGKDGKYVIVRLTSGEVRLVLATNRATIGEVGNAEHSLINWGKAGRNRWRGKRPHVRGSVMNPNDHPHGGGEGKAPVGRPSPMSPWGKKTAGKKTRDKKKASTKFIVRGRKSK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: HDRD_METMA
Sequence: MAKKTPSIDTKNLTAVQLMELDSCTRCGECVKWCPTYAASGQKPGLAPRDKILRWRQFMNKSYGIKAKLFGPTEIPQSELEEFKDDVHGCTTCGICATVCESGINTVELWEALRTNLVKKGIGPFGKQNMFPKLIGQYHNPYMKDQKDRLNWVPPDVKIEDKADVVYFTGCTAGYNQLALAFATARVLNKLGVKFSMLGEEEWCCGSALIRTGQVHVDDVPRELARHNVEALKKKGAKKVLYACAGCFRASKVDWPRLLGEELPFEVVHVAEFLADLIKQDKIKWEKSINKTVTYHDPCHLGRHVGVFDAPRYVLSHIPGVKFVEMDRVKEFQRCCGAGGGVKAGIPDLALGVAESRVKDAVATDADILSSCCPFCKRNLMDGRDSLKVDMVVEDVIELVAEALGLETK
What is the function of this protein?
Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
What are the official names of this protein?
Dihydromethanophenazine:CoB--CoM heterodisulfide reductase subunit D, CoB--CoM heterodisulfide reductase iron-sulfur subunit D, Coenzyme B:coenzyme M:methanophenazine oxidoreductase subunit D.
What is the protein family that this protein belongs to?
Belongs to the HdrD family.
What are the subcellular locations of this protein?
Cell membrane. Note=Membrane-bound.
Protein: TATD_CITRI
Sequence: MFDIGVNLTSSQFVKDHDEVVARAYAAGVNGLLLTGTNLYESQQAQRLAQHYPHCWSTAGVHPHDSSEWRADTGEAIVALAALPEVVAIGECGLDFNRNFSTPQAQEHAFEAQLRIAAELQMPVFMHCRDAHTRFLALLDPWLDKLPGAVLHCFTGTRQEMQECLERGLYIGITGWVCDERRGLALRELLPLIPTEKLLIETDAPYLLPRDLSPKPASRRNEPAYLPHILQRIAHWRGEDPQQLAAATDANAEKLFGITLKSA
What is the function of this protein?
3'-5' exonuclease that prefers single-stranded DNA and RNA.  May play a role in the H(2)O(2)-induced DNA damage repair.
What are the official names of this protein?
3'-5' ssDNA/RNA exonuclease TatD, DNase TatD.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. TatD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCR3_MOUSE
Sequence: MAFNTDEIKTVVESFETTPYEYEWAPPCEKVRIKELGSWLLPPLYSLVFIIGLLGNMMVVLILIKYRKLQIMTNIYLFNLAISDLLFLFTVPFWIHYVLWNEWGFGHYMCKMLSGFYYLALYSEIFFIILLTIDRYLAIVHAVFALRARTVTFATITSIITWGLAGLAALPEFIFHESQDSFGEFSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIRLIFVVMIVFFIFWTPYNLVLLFSAFHSTFLETSCQQSKHLDLAMQVTEVIAYTHCCINPVIYAFVGERFRKHLRLFFHRNVAVYLGKYIPFLPGEKMERTSSVSPSTGEQEISVVF
What is the function of this protein?
Receptor for C-C type chemokine.  Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15.  Subsequently transduces a signal by increasing the intracellular calcium ions level.  In addition acts as a possible functional receptor for NARS1.
What are the official names of this protein?
Probable C-C chemokine receptor type 3, C-C CKR-3, CC-CKR-3, CCR-3, CCR3, CKR3, Macrophage inflammatory protein 1-alpha receptor-like 2, MIP-1 alpha RL2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ABFA_ASPNC
Sequence: MVAFSALSGVSAVSLLLSLVQNAHGISLKVSTQGGNSSSPILYGFMFEDINHSGDGGIYGQMLQNPGLQGTAPNLTAWAAVGDATIAIDGDSPLTSAIPSTIKLNIADDATGAVGLTNEGYWGIPVDGSEFHSSFWIKGDYSGDITVRLVGNYTGTEYGSTTITHTSTADNFTQASVKFPTTKAPDGNVLYELTVDGSVAAGSSLNFGYLTLFGETYKSRENGLKPQLANVLDDMKGSFLRFPGGNNLEGNSAENRWKWNETIGDLWDRPGREGTWTYYNTDGLGLHEYFYWCEDLGLVPVLGVWDGFALESGGNTPLTGDALTPYIDDVLNELEYILGDTSTTYGAWRAANGQEEPWNLTMVEIGNEDMLGGGCESYAERFTAFYDAIHAAYPDLILIASTSEADCLPESMPEGSWVDYHDYSTPDGLVGQFNYFDNLNRSVPYFIGEYSRWEIDWPNMKGSVAEAVFMIGFERNSDVVKMAAYAPLLQLINSTQWTPDLIGYTQSPGDIFLSTSYYVQEMFSRNRGDTIKEVTSDSDFGPLYWVASSAGDSYYMKLANYGSETQDLTVSIPGTSTGKLTVLADSDPDAYNSDTQTLVTPSESTVQASNGTFTFSLPAWAVAVLAAN
What is the function of this protein?
Alpha-L-arabinofuranosidase involved in the degradation of arabinoxylan, a major component of plant hemicellulose.  Acts only on small linear 1,5-alpha-linked L-arabinofuranosyl oligosaccharides (By similarity).
What are the official names of this protein?
Probable alpha-L-arabinofuranosidase A, ABF A, Arabinosidase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 51 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL10_XANCB
Sequence: MALNLSQKQEVVAELADIAAKAHSLIAAEYAGITVSQMTAMRKQARETGVFLKVVKNTLAVRAVEGTDFAVAADKLVGPLLYAFSMEEPGAAGRLIKEFAKGNDKLQAKVVSIGGELFPASHVDVLASLPTLDQALAMLARVLSEPAAMFARAVKAVGDKQGGGDEAAAPVAETAEA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: RL4_THEFY
Sequence: MATIEVKDREGAAKGSVELPDEIFAQKVNIPLIHQVVVAQQAAGRQGTHSTKTRGEVRGGGKKPYRQKGTGRARQGSVRAPQFTGGGTVHGPKPRDYAQRTPKKMKAAALRGALSNRAQHGRIHVVSEFVPEDVTTKRTQTALKTLRKITDSDKVLVVLSREDQHNRLALRNLPEVHILDANQVNTYDVLYADDIVFTEAGYQEFLAHAKGSKIAASQEDDQ
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: END4_SALSV
Sequence: MKYIGAHVSAAGGLANAPARAAEIGATAFALFTKNQRQWRAAPLTPQVIDDFKIACEKYHFSAAQILPHDSYLINLGHPVSEALEKSRVAFLDEMQRCEQLGLTLLNFHPGSHLMQIAQEDCLARIAESINIALAQTEGVTAVIENTAGQGSNLGFEFEQLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPEACEKTFAGFGKIVGFQYLRGMHLNDAKSAFGSRVDRHHSLGEGNIGHDAFRWIMQDARFDGIPLILETINPDIWAEEIAWLKAQQIAEAVA
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: RL21_SORC5
Sequence: MYAVIKTGGKQYRVAEGQKLRVEKLVGNAGDKVTFSEVLLVGGDSPKIGKPLVSGASVAAEITGQDRGKKIVVFKFRRRKNYRRKNGHRQPYTELKITGITA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: RL23_SYNE7
Sequence: MAEANIRALADIIRRPIITEKATRLLENNQYTFEVDPRASKPEIKAAIEALFQVKVVGLSTQLPPRKARRVGRFAGHRAQVKRAVARLADGDSITLFPEV
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: MET_BOVIN
Sequence: MKAPAVLAPGILVLLFTFVQKSNGECKEALVKSRMNVNMQYQLPNFTAETSIQNVVLHKHHIYLGAINYIYVLNDKDLQKVAEYKTGPVLEHPDCFPCQDCSHKANLSGGVWKDNINMALLVDTYYDDQLISCGSVHRGTCQRHVLPPNNTADIESEVHCMYSPQADEETNQCPDCVVSALGTKVLLSEKDRFINFFVGNTINSSYLPDYILHSISVRRLKETQDGFKFLTDQSYIDVLPELRDSYPIKYVHAFESNHFIYFLTVQRETLDAQTFHTRIIRFCSADSGLHSYMEMPLECILTEKRRKRSTKQEVFNILQAAYVSKPGAQLARQIGASLNDDILYGVFAQSKPDSSEPMNRSAVCAFPVKYVNEFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEVRNDEYRTEFTTALPRVDLFTGQFNQVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGSLTPHVNFHLDSHPVSPEVIVEHPLNQNGYTLVVTGKKITKIPLNGLGCEHFQSCSQCLSAPSFVQCGWCHDKCVRLEECSSGTWTQETCLPTIYKVFPTSAPLEGGTTLTVCGWDFGFKRNNKFDLKKTRVLLGNESCTLTLTESTTNMLKCTVGPAMNEHFNMSIVISNSRGSVEYSAFSYVDPIITSISPNYGPKTGGTLLTLTGKHLNSGNSRHISIGGKTCTLKSVSHSILECYTPAQSAPTEFSVKLKIDLANREVNSFIYREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVLRMVINVHEAGRNFTVACQHRSNSEIICCTTPSIEQLNLQLPLKTKAFFMLDGIHSKYFDLIYVHNPVFKPFEKPVMISVGNENVLEIKGNDIDPEAVKGEVLKVGNKSCENIHSHSEAVLCTVPSDLLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIVGVVSISIILLLLLGLFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNASQNGSCRQVQYPLTDLSPILTSGDSDISSPLLQNTIHIDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDDKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMEYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDVYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAELRPSFSELVSRISVIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSQDNVSGEDDDDT
What is the function of this protein?
Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand.  Regulates many physiological processes including proliferation, scattering, morphogenesis and survival.  Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules.  Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1.  Recruitment of these downstream effectors by MET leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC.  The RAS-ERK activation is associated with the morphogenetic effects while PI3K/AKT coordinates prosurvival effects.  During embryonic development, MET signaling plays a role in gastrulation, development and migration of muscles and neuronal precursors, angiogenesis and kidney formation.  In adults, participates in wound healing as well as organ regeneration and tissue remodeling.  Promotes also differentiation and proliferation of hematopoietic cells (By similarity).
What are the official names of this protein?
Hepatocyte growth factor receptor, HGF receptor, HGF/SF receptor, Proto-oncogene c-Met, Scatter factor receptor, SF receptor, Tyrosine-protein kinase Met.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single- pass type I membrane protein.
Protein: US420_GAHVG
Sequence: MQRQTGHMEDKKRTGLESQGTENAFSDGRDGKDGLLHEGINEPILIPSTIADLEGIRELVRKFRGRLLPFEKCPDFCLRIGGLEASFHKGQEELLEYCEALYLPQPVKMEIVGIVDDVPCLATGMQLLILVAEGGRGICL
What are the official names of this protein?
Uncharacterized 15.5 kDa protein.
Protein: SIGS_STAAM
Sequence: MKFNDVYNKHHKIIHHLLKKYNISYNYDEYYQLLLIKMWQLSQIYKPSSKQSLSSFLFTRLNYYLIDLFRQQNQLKDVILCENNSPTLTEQPTYFNEHDLRLQDIFKLLNHRERLWLKLYLEGYKQFEIAEIMSLSLSTIKLIKMSVKRKCQHNFN
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival (By similarity).
What are the official names of this protein?
RNA polymerase sigma factor SigS.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family.
Protein: SESN2_BOVIN
Sequence: MIVADSECRAELKGYLPGAGEEQRESRVRRGPRGPSAFIPVEEVLQEGAESLEQHLGLEALMSSGRVDNLAVVMGLHPDYFTSFWRLHCLLLHTDGPLANSWRHYIAIMAAARHQCSYLVGSHMAEFLQTGGDPEWLLGLHRAPEKLRKLSEINKLLAHRPWLITKEHIQALLKTGEHSWSLAELIQALVLLTHCHSLASFVFGCGILPEGDPEGSPAPQAPSPPSEQSTPPSRDSLNHSGGFEAARDVEALMERMRQLQESLLQDEGASQEEMESRFELEKSESLLVTPSVDILEPFANPDMLCFVEDPTFGYEDFTRRGTQAPPTFRAQDYTWEDHGYSLIQRLYPEGGQLLDEKFQAAYSLTYNTIAMHSGVDTSVLRRAIWNYIHCVFGIRYDDYDYGEVNQLLERNLKVYIKTVACYPEKTTRRMYNHFWRHFRHSEKVHVNLLLLEARMQAALLYALRAITRYMT
What is the function of this protein?
Functions as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway through the GATOR complex.  In absence of leucine, binds the GATOR subcomplex GATOR2 and prevents TORC1 signaling.  Binding of leucine to SESN2 disrupts its interaction with GATOR2 thereby activating the TORC1 signaling pathway.  This stress-inducible metabolic regulator also plays a role in protection against oxidative and genotoxic stresses.  May negatively regulate protein translation in response to endoplasmic reticulum stress, via TORC1.  May positively regulate the transcription by NFE2L2 of genes involved in the response to oxidative stress by facilitating the SQSTM1-mediated autophagic degradation of KEAP1.  May also mediate TP53 inhibition of TORC1 signaling upon genotoxic stress.  Moreover, may prevent the accumulation of reactive oxygen species (ROS) through the alkylhydroperoxide reductase activity born by the N-terminal domain of the protein.  Was originally reported to contribute to oxidative stress resistance by reducing PRDX1.  However, this could not be confirmed.
What are the official names of this protein?
Sestrin-2.
What is the protein family that this protein belongs to?
Belongs to the sestrin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUC_BACAC
Sequence: MGKRLLDKLWERHVVTTNENGLDLLYIDLHLVHEVTSPQAFEGLRLTNRTVRRPDLTFATMDHNIPTKDVWNITDRIAKQQLDTLRENCKQFQVPLADIGDEEQGIVHVIGPELGLTQPGKTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLWQRKPKAMGIELKGKLQKGVYAKDIILHLLSKYGVAVGTGYVMEFYGETIGTMEMEERMTLCNMAIEGGAKAGIIAPDEKTFAYVKGRKYAPRDYETFEKKWFELYTDADAIYDLHISIDVTDLAPYVTWGTNPSMGVRIDEKLPEKHDVNDERAFSYMGLIPGQSTYDIPVQHVFIGSCTNSRLSDLEIAASVVKGRKVKEGVRALVVPGSKRVRDAAMQKGLHHIFEEAGFEWREPGCSMCLGMNPDQVPEGEHCASTSNRNFEGRQGKGARTHLVSPAMAAAAALYGHFVDIRKESYDGAISYS
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: GPR_SCHGR
Sequence: AYPAAHQGYPAHVGYARVGYGGYPSYGYPA
What is the function of this protein?
May be involved in the remodeling of the basement membranes or of the vitellin membrane of the ovarian oocytes.
What are the official names of this protein?
Glycine-proline-rich protein.
Protein: NQRE_METCA
Sequence: MEAYINLFIKSVFIENMALSFFLGMCTFIAVSKKIETAVGLGIAVVIVQTLTVPANNLIYTYLLKEGALSWAGLHDVDLSFIALMACIGVIAAMVQILEMVLDKFFPALYNALGIFLPLITVNCAILAGSLFMIERDYNFSESVVYGVGSGFGWALAITAMAGVREKLKYSDVPAGLRGLGITFISAGLMALGFMAFSGIQL
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit E, Na(+)-NQR subunit E, Na(+)-translocating NQR subunit E, NQR complex subunit E, NQR-1 subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATS4_RAT
Sequence: RRTKRFASLSRFVETLVVADDKMAAFHGAGLKHYLLTVMAAAAKAFKHPSIRNPVNLVVTRLVILGSGQEVPQVGPSAAQTLRSFCTWQKGLNPPNDSDPDHFDTAILFTRQDLCGVSTCDALGMAGVGTVCDPARSCAIVEDDGLQSAFTAAHELGHVFNMLHDNSKPCANLNGQGSSSRHVMAPVMAHVDPEEPWSPCSARFITDFLDNGYGHCLLDKPEAPLHLPVTFPGKDYDADRQCQLTFGPDSSHCPQLPPPCAALWCFGHLNGHAMCQTKHSPWADGTPCGPAQACMGGRCLHVDQLKDFNIPQAGGWGPWGPWGDCSRTCGGGVQFSSRDCTKPVPRNGGKYCEGRRTPFRSCNTKNCPHGSALTFREEQCAAYNHRTDLFKSFPGPMDWVPRYTGVAPRDQCKLTCQARALGYYYVLEPRVADGTPCSPDSSSVCVQGRCIHAGCDRIIGSKKKFDKCMVCGGNGSSCSKQSGSFKKFRYGYSDVVTIPAGRTHILVRQQGGSGLKSIYLALKLADGSYALNGEYTLMPSSTDVVLPGAVSLRYSGRTAASETLSGHGPLAQPLTLQVLVAGNPQNVRLRYSFFVPRPVPSTPRPPPQNWLQRRAEILEILRKRTWAGRK
What is the function of this protein?
Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover.  May play an important role in the destruction of aggrecan in arthritic diseases.  Cleaves aggrecan at the '392-Glu-|-Ala-393' site.
What are the official names of this protein?
A disintegrin and metalloproteinase with thrombospondin motifs 4, ADAM-TS 4, ADAM-TS4, ADAMTS-4, Aggrecanase-1.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: TRPC_BACCR
Sequence: MGTILDKIVEQKKKEVAELYEIYTPVKTKRKTQSLVEALQQFTVIAEVKRASPSKGDINLHVDVRKQVGTYEKCGAGAVSVLTDGQFFKGSFHDLQTAREESNIPLLCKDFIIDKIQIDRAYEAGADIILLIVAALTKEKLKELYSYVLEKGLEAIVEVHDEQELETAIVLNPHVIGINNRNLKTFEVDLSQTEKLGKRLNEEKLLWISESGIHSKEDIIRVKRAGAKGVLVGEALMTSSSISSFFEDCKVNI
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: Y612_MYCPN
Sequence: MRSYHYLPLLGFVAFPTLLANASLDKNLVDSSLYISNSAHHNQGFTVGIKLKDSYFRKDFNFENPLIYKPNNKTTFGWNYSTLWTQLADGYYDRYNQLLRENNFNWYNNIYYIKDVNLGIESSYTSSLAWNKTFSYPGVRNSFKSDIHDLQYFHFHNDSKSGFGPSRINDPWYPQHDKYVTLSAGRTAEEAKNAGWSIPYNLETQRLFSPVWNRNKDFKWINVFFGFMNRSLSVKSPNINDIVQNAKWIKQGKNGNYFIIFNAYAITQNDGFFEDRPNNIFIATLWNNWWLESTPIYIYRVFWEVELIKTPRVFEQDNVQWNEPVLPKETWVFSIDNKQANAYWSSSNGFKDKVIKDRKIMEAFTRNRQVTQSILNMGKNVVVKPLTDDEEQSLFSNKWDIFKYTPIIPVNAQRFGVDFYVEQHNADLKPPISFSQLSRLWLSQLQFDPNSVVDTLSKTFNEKDLSQKDQLQIMFKKEFTQAIAQISKLNEEIDLATDKATALQKFDSLKSKDSNVNFASLQYLYDLLGMEPTNKEHLIFIRNLPEMLQTIFARAKLLAKVKIGDTLQEITLLKNNVNVFDIKTWEKYLTPQQHASNEYTINFLSLDFIVDGYESENLHFQVVDQLFGAVKNLPTINKIPEGYQYKFKYRSNFSNQQFKEKDFSVPLHKAIKSFSVGELKQRMEKLNDFEKQQIVFVIKNSFAGVDKTVLDVDANSLTFVEDPRQYKLDLGNMNENKGFFYVLADIHNSNELFKLGSTIDPEIIKGQIYFVKQNQIKPNTRTYLFKINTRKLLLDKQKLWFKPHLETQTVSFMFDEFEIGKLDIETSNIQLIDDYEFEFQSDFSLQDEQVLLEKLNIVLSQMNLHVETKNARLNPVNKMAYLTVLKNNQKFNLEFHVDRYTSQLSIQAMLGSQRLFAINYDLKLSQNKQMLYLINKDGLEKSVWFNIKNDSQTKLAQQLARFLKENNFQFRQKPVFDFHTQNKAFALEKLDNKDDTD
What are the official names of this protein?
Uncharacterized protein MG414 homolog.
What is the protein family that this protein belongs to?
Belongs to the MG414/MG415 family.
Protein: CSOSD_HALNC
Sequence: MNNIDLRVYSFIDSLQPQLASYLATSSQGFLPVPGDACLWIEVAPGMAVHRLSDIALKATNVRLGEQVVERAFGSMEIHYRNQSDVLASGEAVLREINHAQEDRLPCRIAWKEIIRAITPDHATLINRQLRKGSMLLPGKSMFILETEPAGYIVQAANEAEKAAHVTLIDVRAFGNFGRLTMMGSEAETEEAMRAAEATIASINARARRAEGF
What is the function of this protein?
Unlike beta-carboxysomes, alpha-carboxysomes (Cb) can form without cargo protein.  CsoS2 is essential for Cb formation and is also capable of targeting foreign proteins to the Cb.  The Cb shell assembles with the aid of CsoS2; CsoS1A, CsoS1B and CsoS1C form the majority of the shell while CsoS4A and CsoS4B form vertices.  CsoS1D forms pseudohexamers that probably control metabolite flux into and out of the shell.
What are the official names of this protein?
Carboxysome shell protein CsoS1D.
What is the protein family that this protein belongs to?
Belongs to the EutL/PduB family.
What are the subcellular locations of this protein?
Carboxysome. Note=This bacterium makes alpha-type carboxysomes.
Protein: APT_ERWT9
Sequence: MTATAQQLEFLKNSIQSIPDYPKPGILFRDVTSLLEDPKAYALSIELLVERYRHAGITKVVGTEARGFLFGAPVALGLGVGFVPVRKPGKLPRKTFAEDYALEYGTDTLELHCDAIQPGDVVLVVDDLLATGGTIEATVNLIRRAGGSVKDAAFIINLFDLSGEARLKALGVESYSLVSFPGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI_PSYA2
Sequence: MNDTKDNKVYSSARHSKYWQQLQTLAESPWSLAALFAQDNTRTQHFSMQAGALYMDYSKQCIDDAVLENLLNLANSCELAARIQSLLQGAMVNTSEERAALHTALRLPATASLQLDTQDVVADVHQSLLQVERLSERVRSGTWRGFSGQAITDVVNIGVGGSDLGPLMATTALDEWADTCVEVHFVSNMDGTQLDNLLKHLNPETTLFIISSKSFGTVDTLSNAKTALSWLLATAKLRAGTEDSVRRRHFIGISANGQKMSAWGIHPEHQLQLWEWVGGRFSLWSAIGLAIAIRIGMSGFKELLAGAHSMDDHFAQADFAKNVPVLLGLIAVWNSTFLQVNAHTVLPYDGRLSYLPSYLTQLEMESNGKSVTQHGDRIDYDTCPILWGEIGSNAQHAFYQLLHQGTQQVSCDFIACVRRYSDEAKNTPLQQQHELSLANCLAQSRVLAFGNAAIAESDGQVACDADKYKYYRGNQPSTTLLLDELTPHSLGALIALYEHKVYVMASIWDINPFDQWGVEMGKQMAESVHDAMQQERGAQFDTSTNQLLKHIKELS
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAB8_OLDAF
Sequence: GSVLNCGETCLLGTCYTTGCTCNKYRVCTKD
What is the function of this protein?
Probably participates in a plant defense mechanism.  Inhibits the cytopathic effects of the human immunodeficiency virus.  Has no hemolytic activity.
What are the official names of this protein?
Kalata-B8.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Bracelet subfamily.
Protein: YIDD_ACIAD
Sequence: MVRILHWLIRFYQIAISPMLGPRCRYIPTCSQYSLEAIHTHGAMKGTWLAIHRVCRCHPWGGSGYDPVPPKAIRFISFQQIDSQMLHVTVPFRERLLNLNHSNHLG
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.