PharMolix/UniProtQA huggingface dataset:
Protein: DHA_MYCTO
Sequence: MRVGIPTETKNNEFRVAITPAGVAELTRRGHEVLIQAGAGEGSAITDADFKAAGAQLVGTADQVWADADLLLKVKEPIAAEYGRLRHGQILFTFLHLAASRACTDALLDSGTTSIAYETVQTPDGALPLLAPMSEVAGRLAAQVGAYHLMRTQGGRGVLMGGVPGVEPADVVVIGAGTAGYNAARIANGMGATVTVLDINIDKLRQLDAEFCGRIHTRYSSAYELEGAVKRADLVIGAVLVPGAKAPKLVSNSLVAHMKPGAVLVDIAIDQGGCFEGSRPTTYDHPTFAVHDTLFYCVANMPASVPKTSTYALTNATMPYVLELADHGWRAACRSNPALAKGLSTHEGALLSERVATDLGVPFTEPASVLA
What is the function of this protein?
Catalyzes the reversible reductive amination of pyruvate to L-alanine.  However, since the physiological environment of M. tuberculosis has a neutral pH, it can be assumed that the enzyme catalyzes exclusively the formation of L-alanine.  May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer (By similarity).
What are the official names of this protein?
Alanine dehydrogenase, 40 kDa antigen, TB43.
What is the protein family that this protein belongs to?
Belongs to the AlaDH/PNT family.
What are the subcellular locations of this protein?
Secreted.
Protein: ECFA1_CLOTE
Sequence: MDSKMIECKNVVYKYEDSNENKFIIAVDDVSFSIDKGEFVVILGRNGSGKSTMAKHMNALLVPTEGKVYVDKMDTLDEENTWNIRNKAGMVFQNPDNQIVATIVEEDVAFGPENLGVEPKEIRTRVENSLKRVKMFEYKKHAPHLLSGGQKQRVAIAGVLAMMPECIVFDEPTAMLDPSGRKEVINTIKELNDEYGITIVLITHYMEEAVEADRVIVMDTGKLVMEGNPREIFSNVKAMKRIGLDVPQVTELAYELKKEGININSDILTIDEMVNELCRLK
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA1, ECF transporter A component EcfA1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GLMM_NEISU
Sequence: MAKKYFGTDGVRGEVGQFPITPDFVLKLGYAAGQVLVQHDGGQKPTVLIGKDTRISGYMLEAALVAGFTAAGVNVIQTGPLPTPGVAYLTRALRLSAGVMISASHNVYSDNGIKFFAEGGVKLSDEIELEIEAKIDEEMKTQPSARLGRARRINGADDRYIEFCKSTFPSHLDLRGLKLVVDTAHGAGYDVAPKVFHELGAQVVSIGDEPNGYNINEKCGATHPKALQAAVLQNEADYGIALDGDGDRLMMVDRNGKVYDGDSLIYVIAKARAREGINIGGVVGTVMTNMAMEIALKEQGVDFCRAKVGDRYVLEQLNQRGWLIGGEASGHILCMDKHNTGDGIISALQVLAALQMLNQDLATICADWQPYPQTMINVRIQKGQKWQEASKDVLAEVEKELEGKGRVVLRASGTEPVVRVMVEARQADWAKKGAERIAAAITGKQ
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: Y893_BACCN
Sequence: MLYLHDVWVNWFEGEENGYNVCHFYEWRKDDTIELLDQVPLLKVDATLYHYIENELLELPQQLLEDVHHKAYIRKNHERLQQEYCFVVTDGRGIIAVDTIGYNVPIRKSRLIPRQEQMVYEMVENVQAEKYKFQMEETEKEHHILSPSPHIMNGLTRKERQLKQLLFMALDQLHTTKNPAEIRYWYTEWDPSAYGAVQHMEFEDVWKQLYEEAKNGWSEKHEQLCERLVKGQPFFEKLWEMENEQKVN
What are the official names of this protein?
UPF0736 protein Bcer98_0893.
What is the protein family that this protein belongs to?
Belongs to the UPF0736 family.
Protein: BMP6_HUMAN
Sequence: MPGLGRRAQWLCWWWGLLCSCCGPPPLRPPLPAAAAAAAGGQLLGDGGSPGRTEQPPPSPQSSSGFLYRRLKTQEKREMQKEILSVLGLPHRPRPLHGLQQPQPPALRQQEEQQQQQQLPRGEPPPGRLKSAPLFMLDLYNALSADNDEDGASEGERQQSWPHEAASSSQRRQPPPGAAHPLNRKSLLAPGSGSGGASPLTSAQDSAFLNDADMVMSFVNLVEYDKEFSPRQRHHKEFKFNLSQIPEGEVVTAAEFRIYKDCVMGSFKNQTFLISIYQVLQEHQHRDSDLFLLDTRVVWASEEGWLEFDITATSNLWVVTPQHNMGLQLSVVTRDGVHVHPRAAGLVGRDGPYDKQPFMVAFFKVSEVHVRTTRSASSRRRQQSRNRSTQSQDVARVSSASDYNSSELKTACRKHELYVSFQDLGWQDWIIAPKGYAANYCDGECSFPLNAHMNATNHAIVQTLVHLMNPEYVPKPCCAPTKLNAISVLYFDDNSNVILKKYRNMVVRACGCH
What is the function of this protein?
Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes including cartilage and bone formation (PubMed:31019025).  Also plays an important role in the regulation of hepcidin/HAMP expression and iron metabolism by acting as a ligand for hemojuvelin/HJV (PubMed:26582087).  Initiates the canonical BMP signaling cascade by associating with type I receptor ACVR1 and type II receptor ACVR2B (PubMed:18070108).  In turn, ACVR1 propagates signal by phosphorylating SMAD1/5/8 that travel to the nucleus and act as activators and repressors of transcription of target.  Can also signal through non-canonical pathway such as TAZ-Hippo signaling cascade to modulate VEGF signaling by regulating VEGFR2 expression (PubMed:33021694).
What are the official names of this protein?
Bone morphogenetic protein 6, BMP-6, VG-1-related protein, VG-1-R, VGR-1.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS6_DESRM
Sequence: MLMKRVIPCLDVTAGRVVKGTNFVNLRDAGDPVELAAFYDKEGADELVFLDITASSDGRVTMLDVVRRTAEEVFIPFTVGGGIRTVDDMRLMLKAGADKIGINTAAIKNPRLISEGAIKFGSQCIVVAMDARQVASEKWEVYIHGGRTSTGLDAVEWALKAEELGAGEILLTSMDRDGTKEGFDLALTRTIAQHVKIPVIASGGVGNLEHMARGLTDGMADAALAASIFHFGEYTIRQAKEYLMEQGIPVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLIW_CLOBK
Sequence: MNLNTKYHGCIEYEEKDVIYFEKGIPGFEELKKFIIFPVEDNDVFSVFHSIEKEDMGIIVISPFNIEKDYEIQLEEEQRKKLELQNEKDALVLNTVTLNSDIDKITVNLRAPIIINIKEKIGEQIIINSDKYKVKHPLFKEEA
What is the function of this protein?
Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin.  Binds to flagellin and participates in the assembly of the flagellum.
What are the official names of this protein?
Flagellar assembly factor FliW.
What is the protein family that this protein belongs to?
Belongs to the FliW family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1270_CORGL
Sequence: MRIIKRRVESAADADTTKNQLAFAGVGVYIAQIVAFFMLAVSAMQAFGFSLAGAAIPATIASAAIGLGAQSIVADFLAGFFILTEKQFGVGDWVRFEGNGIVVEGTVIEITMRATKIRTIAQETVIIPNSTAKVCINNSNNWSRAVVVIPIPMLGSENITDVIARSEAATRRALGQEKIAPEILGELDVHPATEVTPPTVVGMPWMVTMRFLVQVTAGNQWLVERAIRTEIISEFWEEYGSATTTSGTLIDSLHVEHEEPKTSLIDASPQALKEPKPEAAATVASLAASSNDDADNADASVINAGNPEKELDSDVLEQELSSEEPEETAKPDHSLRGFFRTDYYPNRWQKILSFGGRVRMSTSLLLGALLLLSLFKVMTVEPSENWQNSSGWLSPSTATSTAVTTSETSAPVSTPSMTVPTTVEETPTMESNVETQQETSTPATATPQRADTIEPTEEATSQEETTASQTQSPAVEAPTAVQETVAPTSTP
What are the official names of this protein?
Uncharacterized protein Cgl1270/cg1434.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: IF3_SHEB8
Sequence: MKIKKTAGRQPAPNRINEEITGVPEVRLTGIDGEAIGVVSIRDAQNLADEAGVDLVEISPNAEPPVCRIMDYGKFLFDKAKSAKEQKKKQKQVQVKEIKFRPGTDENDYQVKLRNLIRFLEDGDKAKITLRFRGREMAHQNLGMDLLNRIKADLDEYAVVESFPKMEGRQAIMVLAPKKK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI1_NEIMB
Sequence: MKHLHDLPAWSKLWNHFDDSKTLHMREMFEQDPQRAERYWLQVGGLTLDYSKNRINDETMSLLFELAREAGVPERMRQMFHGEKINTTENRAVLHVALRNRTNSPIVVDGEDVMPKVNRVLQRMGEFAHEVRSGSWLGYTNQVITDVVNIGIGGSDLGPLMMCTALKPFGHPRLNMHFVSNVDGSQLRDVLSKVHPETTLFIIASKTFTTQETLTNALTAREWFLNHAGDEEAVAKHFAAVSTNQKAVAEFGIDTANMFEFWDWVGGRYSLWSAIGLPIMLYLGEENFIEMLNGAHLMDQHFINTPLERNLPVILALIGIWYINYYGGGSHVIAPYDQHLHRLPKFIQQLDMESNGKQVTLDGKAVGHETSPIIWGETGINGQHAFFQLLHQGTHITPIDLIASLEKRSNLPGHHEILLANVFAQAEAFMRGKTPDEVRAELKAQGMDEVRIEELVPHKTFSGNRPTNLILMDKVNPRNMGSLIAMYEHKTFVQGIIWGINSFDQWGVELGKQLAKTILGELTGETGPQKHDSSTERLINLYLQTNRK
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase 1, GPI 1, Phosphoglucose isomerase 1, PGI 1, Phosphohexose isomerase 1, PHI 1.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASSY_BORPD
Sequence: MTTILPNLPVGQKVGIAFSGGLDTSAALLWMRNKGAIPYAYTANLGQPDEDDYDAIPRRAMEYGAENARLIDCRAQLVAEGIAALQAGAFHVSTAGITYFNTTPIGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNPDLKIYKPWLDQLFIDELGGRAEMSEYMRQAGFDYKMSAEKAYSTDSNMLGATHEAKDLEQLNSGIRIVKPIMGVAFWRDDVAVKAEEVSVRFEEGQPVALNGVEYADPVELMLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGLALLFIAYERLVTGIHNEDTIEQYRESGRKLGRLLYQGRWFDPQAIMLRETAQRWVARAVTGEVTLELRRGNDYSLLNTESPNLTYAPERLSMEKVENAPFTPADRIGQLTMRNLDITDTRDKLFTYVKTGLLASSGGAALPQLKDAKK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEF_CAMJE
Sequence: MRYGEKEIKEFDVENMEIWPNDAKNDYIIKITLPEFMCCCPRSGYPDFATIYLEYMPDKFVVELKAIKLYINTFMYRNVSHEASINEIYNTLKDKLKPKWIKVVGDFNPRGNVHTVIECRSDMVVPK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31_MYCGE
Sequence: MKKAIHFQSQPVVFNCASCNSNFTIDSTAKQKDLAIDICGKCHPFYIGQLTKQTVHGRAEKLSQKFNAGKAFLENKTKKSNQAKVEKQTRHRSINEL
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: LPXB_RALSO
Sequence: MTQPPAAPARRIGMAAGEASGDLLASLLLKGLHARLPRDVAYEGIGGARMAEQGFASHWPMHKLSVNGYVEVLGQLREILAIRRELKQNLLADPPMAFIGVDAPDFNFNVEIAMRRAGVPVVHFVSPSIWAWRAGRIKTIARAVDHILCLFPFEPEIYARAGIPATYVGHPLADEIPLEPDVEGARSRLGLPLGRKVVAVLPGSRNSEVKLLGPTLFAAMARMQAVEPDLAFVLPAANAMLRERIDAMRAEHPGLHLWVVDGQSHAAMEAADVILLASGTATLEAALYKKPMVITYKVPWLTAQIMKRKGYLPYVGLPNILSGRFVVPELLQDDATPEALARETLLQLSDHANAAFLREHFTQMHLTLKQNMADIGAQVVVDLLRGRGKL
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: FABZ_PARMW
Sequence: MTDSPASDAAQSSVVLTSEQIAGLLPHRYPFALVDRVIAHEPGVSATGIKNVTVNEPQFQGHFPGRPLMPGVLIVEAMAQVGGLIVTQMPDLPKGLFVFAGIDGVRFRRPVVPGDQLVIHCELLSLKRKRFGKVKAEAKVDGELVCSGELMFSLVD
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMM_SALSV
Sequence: MNKVVLLCRPGFEKECAAEITDKAGKREIFGFARVKENAGYVIYECYQPEDGEKLISELPFSSLIFARQWFVVGELLQHLPPEDRITPIVGMLQGVVEKGGELRVEVADTNESKELMKFCRKFTVPLRAALRDAGVLTNYETPKRPVVHVFFIAPGCCYTGYSFAHNNSPFYMGIPRLKFPSDAPSRSTLKLEEALHVFIPEDEWDERLANGMYAVDLGACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFRYRPNRNNISWMVCDMVEKPAKVTALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYLQAQLDEHGVNAQIQARQLYHDREEVTVHVRRLWAAVGGRRDER
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_PICTO
Sequence: MVRNEIKAVKEESKKRNFLESIEISINLKDVDLSDPKKRINEEIVLPSGRGKDLKVALISSEEMKLKAKNADYTFSPEDVSKFVDDKKSFKKLANKVDFFVAESTLMSSIGKNLGVILGPRGKIPRPVPPGQDPTALIENLKKSVRARSRDRRTFHVPIGTREMSDDDLYNNFVTVYKRIVSRLDKGPGNIDSIYIKTTMGKAIKVETGDLND
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: BETA_STAAC
Sequence: MSNKNKSYDYVIIGGGSAGSVLGNRLSEDKDKEVLVLEAGRSDYFWDLFIQMPAALMFPSGNKFYDWIYSTDEEPHMGGRKVAHARGKVLGGSSSINGMIYQRGNPMDYEGWAEPEGMETWDFAHCLPYFKKLEKTYGAAPYDKFRGHDGPIKLKRGPATNPLFQSFFDAGVEAGYHKTPDVNGFRQEGFGPFDSQVHRGRRMSASRAYLHPAMKRKNLTVETRAFVTEIHYEGRRATGVTYKKNGKLHTIDANEVILSGGAFNTPQLLQLSGIGDSEFLKSKGIEPRVHLPGVGENFEDHLEVYIQHKCKEPVSLQPSLDIKRMPFIGLQWIFTRTGAAASNHFEGGGFVRSNNEVDYPNLMFHFLPIAVRYDGQKAAVAHGYQVHVGPMYSNSRGSLKIKSKDPFEKPSIRFNYLSTEEDKKEWVEAIRVARNILSQKAMDPFNGGEISPGPEVQTDEEILDWVRRDGETALHPSCSAKMGPASDPMAVVDPLTMKVHGMENLRVVDASAMPRTTNGNIHAPVLMLAEKAADIIRGRKPLEPQYIDYYKHGVHDENEGAIEVKPYAK
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
What are the official names of this protein?
Oxygen-dependent choline dehydrogenase, CDH, CHD, Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: MURG_CLONN
Sequence: MSKYKIIMTGGGSAGHVTPNLALVPKLKELGYEIQYIGTENGIERKIIESENIKYHIISSGKLRRYFDIKNFSDPFKVLKGVFEAKKIIKREKPNIVFSKGGFVSVPVVIGARLNRIPVISHESDMTPGLANKLAAPFCNKVCVTFPETLKYIKDNKGVLTGTPIREELFKGSKIKGYEICKFKDTTKPVLMIIGGSLGSKVINKSVRDALSNLIKKYNIIHICGKGNLDESLQNVEGYVQFDYVKDELPHLMATADLFISRAGANVIFELLALKKPNLLVPLSAKASRGDQILNAKSFEKSGYSMVIEEESLNSEVITNKIDELFKEKQKYIKNMNSSSANNCVDKIISLIEKYKK
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ACPH1_APIME
Sequence: MSVIAILAMVVGVQAELKQINVIFRHGDRIPDEKNEMYPKDPYLYYDFYPLERGELTNSGKMREYQLGQFLRERYGDFLGDIYTEESVSALSSFYDRTKMSLQLVLAALYPPNKLQQWNEDLNWQPIATKYLRRYEDNIFLPEDCLLFTIELDRVLESPRGKYEFSKYDKLKKKLEEWTGKNITTPWDYYYIYHTLVAEQSYGLTLPSWTNNIFPRGELFDATVFTYNITNSTPLLKKLYGGPLLRIFTKHMLDVVSGTQKKKRKIYLFSGHESNIASVLHALQLYYPHVPEYSSSIIMELHNIEGTHYVKIVYYLGIPSEARELQLPGCEVLCPLYKYLQLIENVIPSNEELICDKRFVDESANNLSIEELDFVKLNLIRIAGTENK
What are the official names of this protein?
Venom acid phosphatase Acph-1.
What is the protein family that this protein belongs to?
Belongs to the histidine acid phosphatase family.
What are the subcellular locations of this protein?
Secreted.
Protein: QUEC_RICRO
Sequence: MKKKAVILLSGGPDSTTVLEIVSKTDYEIYALSFNYHRRNSLEVQKIQGLIKDYNVKQHRVINIDLQSFIGSALTDDNIDVPKFKNTDQLPSDIPVTYVPARNTIFLSYALGVAEVIGARDIFIGVHTNDYTNYPDCRPEYIKSFEAMANLATRVGVNGEKITIHAPLINMTKEQIIKKGLELGVDYSKTISCYDPTEDGLSCGQCLSCIVRLDAFKKNNVQDPIQYV
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: NU4LC_TRACE
Sequence: MLEHVLVLSAYLFSVGLYGLITSRNMVRALICLELIFNAVNINFVTFSDFFDSRHLKGSIFAIFVIAIAAAEAAIGLAILSAIYRNRKSIHINQSNLLTK
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic, NAD(P)H dehydrogenase subunit 4L, NADH-plastoquinone oxidoreductase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: TILS_ALKEH
Sequence: MAPTPELSPETLARHLAVLGPASGYCVAYSGGLDSTVLLHLMAALSAARELPLRAVHIHHGLQPQADAWAEHCRQQAAALGVDCLVLPVEVRRDSGEGLEAAARQARYAALASHLQSGEALLTAHHADDQAETVLLHLLRGSGPRGLAGMRAQRPLGRGRLLRPLLPWPRERLRAYGDTHALCWVEDPSNAHVAHDRNWLRHTLWPVLTQRWPDASRRVGRAAGEQAEAEALLRELAGEDLARHPPGPGLAVSVLARLSPARARNLVRHWLLMSGLRPPPRARLEQGLADLIRAGRDRQPVLTWPEGELRRYRDRIHRLPAGGPPPWPGPDREWDLRVPLVVPGVGVLRLVRADEGIAPSLIGAEGLSVGRRRRGERCQLAHDPGHRPLSKRFQEAGIPPWERDRVPILRRGEEVVAIANLGTAKRFTARPGYRLICEEHGPDGG
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GIMA6_MOUSE
Sequence: MDWLYRKTLGSIGSCSIETFPWPFYSFFQRIYISTPPGKPENSPETSATEVGEQRPSCLSASPVVEEEECEHRPEKNPTRQWPLDSGQGLTKGLKEKKLTPKRLQLLLVGKTGSGKSATGNSILGRQAFESKISARPVTTTFQKGTREFEGKELEVIDTPDIFSPQNQPEATAKKICDLLASPGPHAVLLVIQVGRYTAEDQAVARCLQEIFGNTILAYTILVFTRKEDLAEGSLEEYIQENNNKSLDVLDVACERRHCGFNNKAQGDEQEAQLKKLMEEVELILWENEGHCYTMEFPNVPSKTL
What are the official names of this protein?
GTPase IMAP family member 6, Immunity-associated nucleotide 6 protein, IAN-6, mIAN6.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: PCKG_ACIAD
Sequence: MTQVNAPEFVRHPKLIAWVEEIAKLTKPAKIEWCDGSDEEYQRLIDLMIANGTMQALNQEKHPGSYLANSDPSDVARVEDRTFICSEKQEDAGATNNWEAPEVMRAKLNGLFDGCMQGRTMYVVPFSMGPLGSHIAQIGIELTDSPYVAVSMRKMARMGKAVYDVLGTDGEFVPCVHTVAAPLAEGQKDVAWPCNPEKYIVHYPETREIWSYGSGYGGNALLGKKCLALRIASAMGREQGWLAEHMLILGVTNPKGEKHYIAAAFPSACGKTNFAMLIPPAGYEGWKIETVGDDIAWIKPGEDGRLYAINPEAGFFGVAPGTNTKTNPNCMATLHKDVIYTNVAVTEDGQVWWEGLSKEVPANLTNWKGQPHVAGEKAAHPNARFTVAAGQCPSIDADWENPAGVPISAFIFGGRRADTVPLVSEAFDWVDGVYKAATMGSETTAAAVGQQGIVRRDPFAMLPFAGYNMADYFDHWLQLGQQVGEKAEAAGNKLPKIFNVNWFRRDAEGNFVWPGFGQNMRVLEWMIDRVEGRANAVETPIGYVPTYEDLNWTGTDFSKEEFDLITSQSKDQWITEIESHTELFNKLGERLPKALKERQDQLLQAVQKI
What is the function of this protein?
Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase [GTP], PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_DESVM
Sequence: MRRVILTTGGTGGHIFPALAVAEEITRRYPKARILFLGGQYGPEADLAARAGLEYVGLPVRGVMGRGLRALAAAGAMGLGVWRAVSVVRRFDPDIAVGFGGYAAFAGVLAARLCGRPAAIHEQNAIPGLTNRLLGHVVQRVFLSLPDTTGVFPARRCVPTGNPVRTAIVAAGAAGAAGAAEKGGVSRSAHSRRLLVMGGSLGARAINEAVVAALPALRDAGVELWHQTGVADWERVRAGYKQAGISEARVEAFIDDVASAYTWADLVLCRAGATSVAELAVAGKPSVLVPFPFATHNHQLHNARHVADAGAALVVEQKDVSPGADGRPAVALDRVLVELLADRERLADMGRAARAMGRPQAAAAVVDGMEAILAGRGARGVR
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HIS5_PSEF5
Sequence: MQTVAVIDYGMGNLHSVAKALEHVGAGKVLITSDASVIREADRVVFPGVGAIRDCMAEIRRLGFDALVREVSQDRPFLGICVGMQALLDHSEENEGVDCIGLFPGQVKFFGKGLIEDGEHLKVPHMGWNEVKQAVDHPLWHNIADLARFYFVHSYYINAGNTRQVVGSGHYGVDFAAALADGSRFAVQFHPEKSHTHGLQLLQNFAAWDGRW
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNF14_HUMAN
Sequence: MSSEDREAQEDELLALASIYDGDEFRKAESVQGGETRIYLDLPQNFKIFVSGNSNECLQNSGFEYTICFLPPLVLNFELPPDYPSSSPPSFTLSGKWLSPTQLSALCKHLDNLWEEHRGSVVLFAWMQFLKEETLAYLNIVSPFELKIGSQKKVQRRTAQASPNTELDFGGAAGSDVDQEEIVDERAVQDVESLSNLIQEILDFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQVKELVEAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQEPGCTMGICSSCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMGSLSRANPYKHFNDPGSPCFNRLFYAVDVDDDIWEDEVED
What is the function of this protein?
Might act as an E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates, which could be nuclear proteins.  Could play a role as a coactivator for androgen- and, to a lesser extent, progesterone-dependent transcription.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF14, Androgen receptor-associated protein 54, HFB30, RING finger protein 14, Triad2 protein.
What is the protein family that this protein belongs to?
Belongs to the RBR family. RNF14 subfamily.