PharMolix/UniProtQA huggingface dataset:
Protein: G6PI_PSYCK
Sequence: MNDTKDNKVYSSARHSKYWQKLKAAAESKWSLAALFAQDNTRTQRFSAQSGALYMDYSKQCLDDTVLESLLNLANSCELSARIQALLQGAMVNTSEERAALHTALRLPTTANLQLDNQDVVADVHQSLGQVERLSERVRSGTWRGFSGKAITDVVNIGVGGSDLGPLMATTALDEWADTCVEVHFVSNMDGTQLDNLLKHLNPETTLFIISSKSFGTIDTLSNAKTALSWLLATAKLRAGTEDSVLRRHFIGISANSEKMSAWGIHPEHQLQLWEWVGGRFSLWSAIGLAIAIRIGMSGFKELLAGAHSMDEHFAQADFAENLPVLLGLIAVWNSTFLQVNAHTVLPYDGRLSYLPSYLTQLEMESNGKSVTQHGDRIDYDTCPILWGEIGSNAQHAFYQLLHQGTQQVSCDFIACVRRYSDKAKNTPLQQQHELSLANCLAQSRVLAFGNAAIAETDSQIACDADKYKYYRGNQPSTTLLIDELTPHSLGALIALYEHKVYVMASIWDINPFDQWGVEMGKQMAESVHDAMQQEGNAPFDTSTNQLLKHIKQLS
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDGC_ECOBW
Sequence: MLWFKNLMVYRLSREISLRAEEMEKQLASMAFTPCGSQDMAKMGWVPPMGSHSDALTHVANGQIVICARKEEKILPSPVIKQALEAKIAKLEAEQARKLKKTEKDSLKDEVLHSLLPRAFSRFSQTMMWIDTVNGLIMVDCASAKKAEDTLALLRKSLGSLPVVPLSMENPIELTLTEWVRSGSAAQGFQLLDEAELKSLLEDGGVIRAKKQDLTSEEITNHIEAGKVVTKLALDWQQRIQFVMCDDGSLKRLKFCDELRDQNEDIDREDFAQRFDADFILMTGELAALIQNLIEGLGGEAQR
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: OXND1_HUMAN
Sequence: MACAAVMIPGLLRCSVGAIRIEAASLRLTLSTLRHLTLTSIMKSKRKTDHMERTASVLRREIVSAAKVCGAASESPSVKSLRLLVADQDFSFKAGQWVDFFIPGVSVVGGFSICSSPRLLEQERVIELAVKYTNHPPALWVHNTCTLDCEVAVRVGGEFFFDPQPADASRNLVLIAGGVGINPLLSILRHAADLLREQANKRNGYEIGTIKLFYSAKNTSELLFKKNILDLVNEFPEKIACSLHVTKQTTQINAELKPYITEGRITEKEIRDHISKETLFYICGPPPMTDFFSKQLENNHVPKEHICFEKWW
What are the official names of this protein?
Oxidoreductase NAD-binding domain-containing protein 1.
Protein: ZNTB_KLEP7
Sequence: MDAIKGSELQIPDAIFAWVLDGQGGVKPLADDDIIDKDKPCWLHLNYTHSDSADWLAATPLLPNNVRDALAGESTRPRVTRIGDGALITLRCINGSTDERPDQLVAMRLYMDERLIVSTRQRKVLALDDVLGDLKEGNGPTDGGSWLVEVCDALTDHASEFIEQLHDRIIDLEDDLLDQQVPPRGFLALLRKQLIVMRRYMAPQRDVYARLASERLPWMSDDQRRRMQDIAERLGRGLDEIDSCIARTAIMSDEIAQIMQESLARRTYTMSLMAMVFLPSTFLTGLFGVNLGGIPGNSWHLGFSLFCLMLVVVIGGVAWWLHRSKWL
What is the function of this protein?
Zinc transporter.  Acts as a Zn(2+):proton symporter, which likely mediates zinc ion uptake.
What are the official names of this protein?
Zinc transport protein ZntB.
What is the protein family that this protein belongs to?
Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RLME_MARSD
Sequence: MKQYRDHYFKRAKKENYPARSVYKLQELDKRFKVFAKGQNVMDLGAAPGSWTLFAAKKVGDTGRVLAVDIQSTDTAFPDNATFLQADVFEDSPELLAAMDKQLPYDLIISDMAPKTTGVKFADQANSLELCERARDIVPSRLKQGGHFIVKIFDGPDVKEYIDSLRKMFSKVKRFKPKSCREESKEFFIVGLGFRGIEG
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_CHLTB
Sequence: MYEYIKGTLTHIDGSYVVIESFGIGYAIMLSERFLVDLRAFMHQEVLIYVHSVIRETEHVLYGFSSRAERECFRLLISFSGIGPKTGLSILNMFPLQELCSIARLENVKAIASVPGIGKKTAEKLMVDLKQKLPTLMPLYLEEPVVPSSTANSSFKEGIGALMNLGFSRLAADRMMTEAVKELSEEASVAELLPIALRKS
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: CHP2_MOUSE
Sequence: MGSRSSHIALIPDVEHIRRETGFSQASLLRLYHRFQALDRDEKGFLSRLDLQQIGALAVNPLGDRIIDSFFPNGSQRLYFAGFARVLAYFRPIDEEDATLRDPKQPEPLNSRMNKLRFAFQLYDLDRDGKISRNEMLQVLRLMVGVQVTDEQLESITDRTVQEADEDGDGAVSFLEFTKSLEKMNIEQKMSIRILK
What is the function of this protein?
Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity.  Binds to and activates SLC9A1/NHE1 in a serum-independent manner, thus increasing pH and protecting cells from serum deprivation-induced death.  Also plays a role in the regulation of cell proliferation and tumor growth by increasing the phosphatase activity of PPP3CA in a calcium-dependent manner.  Activator of the calcineurin/NFAT signaling pathway.  Involved in the cytoplasmic translocation of the transcription factor NFATC3 to the nucleus (By similarity).
What are the official names of this protein?
Calcineurin B homologous protein 2, Hepatocellular carcinoma-associated antigen 520 homolog.
What is the protein family that this protein belongs to?
Belongs to the calcineurin regulatory subunit family. CHP subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell membrane. Note=Exported from the nucleus to the cytoplasm through a nuclear export signal (NES) pathway. May shuttle between nucleus and cytoplasm. Predominantly localized in a juxtanuclear region. Colocalizes with SLC9A3 in the juxtanuclear region and at the plasma membrane (By similarity).
Protein: H17B6_RAT
Sequence: MWFYLVTLVGLYYLLRWYRERQVVSHLHDKYVFITGCDSGFGNLLARQLDRRGMRVLAACLTEKGAEELKSKTSDRLETVILDVTNTDSISAATQWVKEHVGDKGLWGLVNNAGVFQAFAYIEWCRPEDCMSIFQVNLIGLAQVTLSMLFLVKKARGRIVNVSSVLGRVALFGGFYSCSKYGVEAFSDVLRREIRDFGVKVSIIEPGSFKTRMTDAELIIEKTKKTWEATPEHIRESYGQQFFDDFCNTTRRELKKCSTNLSLVTDCMEHALTSKYPRTRYSAGWDARLFFIPLSYLPTSLVDCLLAISRRKPAQAV
What is the function of this protein?
NAD-dependent oxidoreductase with broad substrate specificity that shows both oxidative and reductive activity (in vitro).  Has retinol dehydrogenase activity towards all-trans-retinol (in vitro) (By similarity).  Has 17-beta-hydroxysteroid dehydrogenase activity towards various steroids (in vitro).  Converts 5-alpha-androstan-3-alpha,17-beta-diol to androsterone and estradiol to estrone (in vitro).  Has 3-alpha-hydroxysteroid dehydrogenase activity towards androsterone (in vitro).
What are the official names of this protein?
17-beta-hydroxysteroid dehydrogenase type 6, 17-beta-HSD 6, 17-beta-HSD6, 3-alpha->beta-hydroxysteroid epimerase, 3-alpha->beta-HSE, Oxidative 3-alpha hydroxysteroid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Microsome membrane; Peripheral membrane protein; Lumenal side. Endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side.
Protein: CAN2_CHICK
Sequence: MAGMAAALAKERAAAAGAGRHGQAVPYLGQDFGALRRECLQGGRLFHDPSFPAGPAALGYRELGPNSYKTKGVVWCRPTELCSCPRFIAGGATRTDICQGALGDCWLLAAIASLTLNEEILARVVPRDQSFQDEYAGIFHFQFWQYGEWVDVVVDDRLPTKNGELLFVHSAEGSEFWSALLEKAYAKLNGSYEALSGGTTTEGFEDFTGGIAEWYELQKAPPNLFKIIQKALQKGSLLGCSIDITSAAETEAVTSQKLVKGHAYSVTGAEEVNFRGSIQKLIRIRNPWGEVEWTGKWNDNCPNWSGVDPEVRERLTRRHEDGEFWMAFNDFLRHYSRLEICNLTPDTLASDRYKKWSLLKLDGNWRRGATAGGCRNYPNTFWTNPQYLIKLEEEDEDPDDPEGGCTFLIGLIQKHRRKQRKMGEDMHTIGFAIYEVPPEFSGQTNIHLSKNFFLTNKAREKSNTFINLREVLNRFKLPAGEYIIVPSTFEPNLNGDFCLRVFSEKNANSTVIDDEIEANFEETEIDEDDIEPSFKKLFGQLAGSDAEISAFELRSILNKILAKRQDIKSDGFSIETCKIMVDLLDNDGSGKLGLKEFHTLWTKIQKYQKIYREIDVDRSGTMNSYEMRRALEAAGFKLSCQLHQIIVARFADEDLIIDFDNCVRCLIRLETLYKMFRKLDTEKTGTIELNLINWLFFTVI
What is the function of this protein?
Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
What are the official names of this protein?
Calpain-2 catalytic subunit, Calcium-activated neutral proteinase 2, CANP 2, Calpain M-type, Calpain-2 large subunit, Millimolar-calpain, M-calpain.
What is the protein family that this protein belongs to?
Belongs to the peptidase C2 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=Translocates to the plasma membrane upon Ca(2+) binding.
Protein: ALR_HAMD5
Sequence: MKGATAIINLKSLRHNLEKIQQYAPKSRLMAVVKANAYGHGLLTVAQALKNADYFSVARIEEALTLRSGGIIKPILLLEGFFSLEDLAVLQVNHIETVIHNFEQLVALEKVRLPEPVRVWMKIDTGMHRLGVRLEQADAFYQRLQNCPNVAKPIHIITHLSDVNPHHPVVTDQQIRSFDAFVQGKPGQKSIAASGAILLCPQSHRDVVRPGIALYGISPFEHFIGRDYGLLPVMTLQSPLIAVREHKAGETVGYAGEWISQTATFLGVLAIGYGDGYPQSAPTGTPVWINDRQVPIVGRVSMDMISVDLGRDATDKVGDRAVLWGDQLSLEKVASYIGYTAYELVSKLTGRVAISYVN
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: PTH_CHLTE
Sequence: MKLIVGLGNPELRHAATRHNIGFDVIDHLAGSSTFSSGKGNYRFTKITAPGGPLILVKPMTYMNLSGHAVVAAMNFWKIERENLLVICDDVNIPLGTIRIRAKGSAGGQNGLKHIIQSLGSEEFARLRVGVGGENMPASLSSFVLSKFTAEERKCIDKVIPVCADAVLDFASLGVEHAMTKYNGQVC
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3MGH_XANCP
Sequence: MSLHSPLPRAFYAADARTVAPLLLNKVLVSADGRRGRITEVEAYCGSEDAAAHSFRGMTPRTQVMFGAPGHLYVYFIYGMHWAINAVCGGAPGHAVLIRALEPLAGCDAMHAARGAAPFKSLTTGPGRLAQAFGVSAVDNGLDLTTGVARLWIEDDGTPPPAAPLAGPRIGIRKAVELPWRWVVPGSAYLSRPLPRVSGARASVTGD
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: WHIA_STREM
Sequence: MSFTTTVKEELIHLSASDQTELSAIIKLAGSLGLANQSLNLSITTENAKIARYIYALIEDTYHIIPEIKYHQKTNLKKNRVYTVYLDKQVDKLLADLKLADSFFGIETGIEQQVMSDDDAGRAYLKGAFLAAGTVRDPESGKYQLEIYSVYLDHAQDLAQLMHKFMLDAKVIERKNGAVTYLQKAEDIMDFLIIIGAMSCKEEFEAVKLLREARNDINRANNAETANIAKTITASMRTINNIIKIMDTIGLDSLPVELQQIAQMRVANPDYSLQQIADSLDFAITKSGVNHRLRKINKLAEDL
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: IRK1_CAEEL
Sequence: MTLSVPDCAEMNRIRMSNHRKMSLGSAPLIANGRPSPPPRRTSLAESIRTLAFTARRNSSPLYRKSTKKLKKSRLVGKNGICNVYNTNVPKKDRQYLRDIFTTMIDVKWRWMLMLFASAFVLSWSIFGTTYYLIALVHGDLSLPTPVNHTACVMNLDSVYSSFLFAVETHHTIGYGHRYITTECYLAGAIVCLQAICALLLQSFMVGIVFAKMARPKKRAETIIFSDKAVICLRDGQLCFLCRVGDMRNTHLVEAHVRLQFITDRETNEGEIEPLHQFEMKVGPSIADDDRLFLVWPTTLCHVIDSRSPLYNYNQQTLMSAQFEIIVLLEGIVESTGMTAQAKTSYLPSEVLWGHRFRKLVTYQRSNGSYQIDYDLFHSTYPVRTPAMSPAEFYSSKPNLKDYYCHDSHEHKLEDNRSSDSTPLPSPSPYSYPSTPLNHFQSSSNSPVFSNNHSKFNTEAVTCEAGMLCPPTIVVQCPSTCASPNHMRRTRNQMDKSRTSSSCDLTRPSTALSDLEEECSDSGSPTKCQSPPVVPIHIEIVSET
What is the function of this protein?
Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it.  Required for modulation of the activity of the hermaphrodite-specific neurons (HSNs) by the G-protein coupled neuropeptide receptor egl-6 which in turn controls egg-laying behavior.
What are the official names of this protein?
Inward rectifier potassium channel irk-1.
What is the protein family that this protein belongs to?
Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Perikaryon. Cell projection. Note=Detected in perikarya and neurites of HSNs.
Protein: OTC_CLOB6
Sequence: MFNLKNRNFLTLMDFTPKEINYFLDLARDLKRAKYTGTEVQRMKGKNIALIFEKASTRTRCAFEVGAKDQGAHVTYLGPTGSHIGKKESAADTARVLGRMYDGIEYRGFGQEIVETLAEYAGVPVWNGLTDEDHPTQILADFLTIREHFNKPLNEIKFAYVGDGANNMANALMIGAVKMGMDFRIVSPKEIPTDAALVAKCKEIAAETGAKVTITDNIEEGVKGCDVLYTDVWVSMGEPDSVWESKIKLLTPYRVDMNMIKMTGNPDAKFMHCLPAFHDEETAVGKEIKEKYGLSEMEVSHELFESKYSIVFDEAENRMHTIKAVMVATLGDQ
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCIB_IDILO
Sequence: MALLLEYLPIIAFFVFYKLADIYVATGVLMVGTVLQILALKLLKQPITTRHWVILAVVMLFGAVTLLLRDDWFIKMKVSVVYVAIALMLLGGLIWKKRSPIQAMMGKDIKLPDTAWSRLTYAWIIFCLALAAVNLYIAEFWSQEAWVNFKVFGILGISLVFTIGTGFYMYHHAIDEETQD
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPF_BLOPB
Sequence: MNLNATILGQTISFVLFVWFCMKYVWYPFISIIEKRQKEISDNLVSATHAKTESERVNAEALLCLRQARVKAQEIIKQANKCKMQIINEAKHEAEKEQSRILSQAREQIIYERKRVTDELRKQISELVIEGTEKVIEHSINEMIDIDLLNNIINTLSYKD
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: LEPA_PHOLL
Sequence: MKQIRNFSIIAHIDHGKSTLSDRIIQICGGLTDREMAEQVLDSMDLERERGITIKAQSVTLDYKANDGQLYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAGQGVEAQTLANCYTALDMNLEVVPVLNKIDLPAAEPERVAEEIEDIVGIDATDAVRCSAKTGVGVQDVIERLVKEIPAPEGNSDEPLQALIIDSWFDNYLGVVSLVRIKNGTLRKGDKIKVMSTGQVYNADRLGIFTPKRVDRDVLGCGEVGWLVCAIKDILGAPVGDTLTLARQPAEKPLPGFKKVKPQVYAGLFPVSSDDYEAFRDALGKLSLNDASLFYEPESSSALGFGFRCGFLGLLHMEIIQERLEREYDLDLITTAPTVVYEVETTSHDTLYVDSPSKLPPLNNIEELREPIAECHMLLPQEYLGNVITLCVEKRGVQTNMVYHGKQVALTYEIPMAEVVLDFFDRLKSTSRGYASLDYNFTRFQSSDMVRVDVLINAERVDALALITHRGNAQYRGRELVEKMKELIPRQQFDIAIQAAIGNHIIARSTVKQLRKNVLAKCYGGDVSRKKKLLQKQKEGKKRMKQVGNVELPQEAFLAILHVGKDN
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RUXF_MOUSE
Sequence: MSLPLNPKPFLNGLTGKPVMVKLKWGMEYKGYLVSVDGYMNMQLANTEEYIDGALSGHLGEVLIRCNNVLYIRGVEEEEEDGEMRE
What is the function of this protein?
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.  Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes.  As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs.  As part of the U7 snRNP it is involved in histone 3'-end processing.
What are the official names of this protein?
Small nuclear ribonucleoprotein F, snRNP-F, Sm protein F, Sm-F, SmF.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Note=SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes.
Protein: DNAJ_LEVBA
Sequence: MAQSDLYGVLGVAKDASQDEIKKAYRKLSKKYHPDLNKAPDAAEKFKEVQDAYDVLGDEQKRANYDQSGSADGAQGGFGGFGGGQQGGFGGFGGGGGFDDIFNQFFGGGGGQRNPNAPRPGRDLQYQMDLTFEEAIFGKKTKIKYNREAQCHTCGGNGAKPGTSPVTCHQCGGSGYVTTETNTPLGRMRSQQPCPVCHGTGQEIKEKCPTCGGSGHEEERHEVEVTIPAGVDDGQQMRLQGQGEAGQNGGGYGDLFIIFKVQPSKDFRRDGTEIYFDQDISFVQATLGDDVTVKTVHGDVKLKVPAGTQGGTTFRLRGKGAPRLRGNGNGDEHVTIKVVTPKNLNKGQRDALRDFAKASGESVTGSGKGNLFNKMRDKFNEN
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_STRPD
Sequence: MPKQKTHRASAKRFKRTGSGGLKRFRAFTSHRFHGKTKKQRRHLRKAGLVSSGDFKRIKAMVTGL
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: IRS4_CANGA
Sequence: MHMRLNKRRRNHVQEQMSELPQDAKNDSLAAAQVIFKRHADNANSTPPSPVGLDSAGHLDKQADTAQRVHKVGTPSGTSSSHNSGNEGMHKVTKPLGENTATTAPIAIKQPVRVVRASPTAIVSPTSHTPLDAATAAANVVAEKSKIRTTQQQLQDKKRRDIENAHHAASAAAVTSSNLAVGSPPSQYIPSVPTLNVTSPQMRNSSQNIDRRSKSNEEAHNGHEKMMNSRSNSINSSTIKGSVSEPNTVTPLRQNSPSNMDDIIQKMEAVDIDEGRKNSFVMNGSGDSVDSLKPNVVRRPMRTPSGRRVRPPSPIDKIGSIQEPHLESTGFNDQNDFSEMSSLIDGSSSEDITKIRGSGIRERSPVDGVEHGGMSVNIPMQRSLSSDVLSPSQQAAMVAATKLSPSTQTLPVEELEYLASTGDVSAYKALNKINGTNMAYKGTIPDLIPSRARAQKTSKLKFKIFGGGKNSDRRNNATPIGYDPVMNISTDFGGKKVVESNQNNVKFKTTMRSQKYLGNDNLDDNDLRTQYIDDDDDDDDYDSAYEDLDYSRDDSEAMYKGDRESSNPRSNSLLQSSSYSGKVGFNSNANSGTSINNSGNVSNLDYSLRDGVAEKKKSRRDKIKKKLKSTASVVPYYPHYALTHLASGVSTVNSNLNNSNKNTKWFNEDKPWKSHKDVGFVTSQERKRYEAMWVTNRYLYLNLLPWWPKEEVEKDEDDSASNLNSNASTNVGGVLSDGDNEEDDVTRFLLSLPADGLMLNLVAKDIWERSNLPNDLLKQIYDLVDTRKDGTLNRESFLVGMWLVDQCLYGRKLPQELDPKIWDSVDRWVLNVVNSTMMTALERKQKKKMMKKELKNIKREQKQAIAEQHN
What is the function of this protein?
Positive regulator of phosphatidylinositol 4,5-bisphosphate turnover and negatively regulates signaling through the cell integrity pathway.  Involved in rDNA silencing (By similarity).
What are the official names of this protein?
Increased rDNA silencing protein 4.
What is the protein family that this protein belongs to?
Belongs to the IRS4 family.
Protein: TPIS_UREPA
Sequence: MKYIIANFKMNATQELINHFLNNLTLFDEQKIIIGLAPGDLYLKTFVNLAEIKKVNLYAQNPSLHNKGPYTGQISCLQLLDINIKNALVGHSEIRIDFSQSIIDQKIKISMDLLEQVIICVGETFDAYKQNKSLNFVLNQLANIINYKGLKKIIIAYEPIWAIGTDLELDFKHINYMIEGIKTYLYNCTGINIPILYGGSVNDNNINELCNQKLIDGFLIGNASLDVNVFNKIIDKCK
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBQ_NOCFA
Sequence: MKGALLVAGTTSDAGKSVVVAGLCRMLARRGVRVAPFKAQNMSNNSVVTLDGGEIGRAQALQARACGLEPSVRFNPVLLKPGSDRRSQLVVRGQAVDTVGAADYFRHRTALREVVAAELASLRAEFDVVLCEGAGSPAEINLRATDLANMGLARAADLPVLVVGDIDRGGVLAHLFGTVAVLEPDDQRLIAGFVVNKFRGDVDLLRPGLDRLAELTGRPTLGVLPFAEELWLDAEDSLGTVADAPVGRPRPPVGTEWLTVAAVRLPRISNSTDVEALACEPGVAVRWVSEPSRLADADLVVVPGSKSTVSDLAWLRRTGLGEALRARVTAGRPVLAICGGYQMLGRRIVDEVESGAGEVAGLGVFDLETEFAAPKVLRRVTGMGAGNPVRGYEIHHGRVRRSGDAPWLGLVDAPEAAVDGGEDAVPLTPEGSVTGGAWGTHVHGLLESDGFRRAWLREVAARAGRHGFQVAPDTSVAAVRAGQLDLLADLVEKHLDQDALERILTDGAPTGLPVLTVGQA
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: CBK1_YARLI
Sequence: MTDKWVPGQGQPMYGSQQPHNLMPPPSGLYQQNSNQSNTSLDQQQQFNQQQYNSQQQYQQQQHSQYQQQQQQHQQQQQQQQQQQQQQQQQQQQQQQQHQQHQQQQQQPQQQSVAQQQPSDYVNFTPRPDLLSKTARDRAHNTTQVISTYYKGIVQHAIERHQRRSAAEASVEQATSEERRNRVLTNYGKKETAYLRMRRTRMALEDFVTVKVIGKGAFGEVRLVQKRDNGKIYAMKTMLKKEMDMKEQWAHVKAERDVLADSDSPWIVSLYFSFQDDLYLYLIMEFLPGGDLMTMLIKYDVFSEDITRFYIAECVLAIEAIHKLGFIHRDIKPDNILIDKTGHIKLSDFGLSTGFHKTHSSAYWKKLKDGTSSNPATQMGPPQNTNRQSTYDSIHLTMRQQISTWRKNRRLMAYSTVGTPDYIAPEIFVHQGYGQECDWWSLGAIMFECLVGWPPFCSEQPRETYHKIINWRETLQFPDDVHLSPESEDLIRRLLTSSENRLGRIGGANEIKSHPFFRGVDWSSIREFNAPFVPKLSSITDTSYFPTDELGDVSEYPQQSSRSDRSSDLPFIGYTFSRFDNMTRRNAI
What is the function of this protein?
Protein kinase that seems to play a role in the regulation of cell morphogenesis and proliferation.
What are the official names of this protein?
Serine/threonine-protein kinase CBK1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. COT1 subfamily.
Protein: RL15_RHOCS
Sequence: MKLNELKDNPGARKERMRVGRGIGSGKGKTGGRGVKGQKSRTGVSIKGFEGGQMPLHRRLPKRGFRNIFAKDYAVVNLGKIQAAIEAGRLETGAPVTVDVLRAAGLVKASRDGVRLLAKGTLTAAVTFEVAGASAAAVEAVEKAGGKVVVIGAEPAAAAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: FBPC_BRUA2
Sequence: MTAIRPGSVTFENVTKKFGNFTALPNLSLTVEPGTLVTLLGPSGCGKTTTLRLLAGLEHPTSGRILIGGKDVTNLPANERDVSMVFQSYALFPHMTSLENVAYGLESSGFKKNEARERAEEGLKLVGLGGMGHRLPAELSGGQQQRVAVARALVLEPQVLLLDEPLSTLDARLRRRVRTEIRELQQRLGFTAVYVTHDQDEALAVSDTIIVMKEGGIAQKGSPRDLYEAPASAFIADFMGEANVVPCEVISAENGEAVIRVAGLTHRVPARNAQPGPAQLAIRPNAVTLQPQAGGGFSGTVAHSAYLGDHIEYEIETEHGKLFIVDPAVEQSLPLQTDVSIQFKTRGLAIINQ
What is the function of this protein?
Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Fe(3+) ions import ATP-binding protein FbpC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Fe(3+) ion importer (TC 3.A.1.10) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.