PharMolix/UniProtQA huggingface dataset:
Protein: KDPC_CALS4
Sequence: MGEEIKRTIKFTLVFMVLLGLVYPFVMTGIANLLFPYQAKGSIIKVDGKPVGSELIGQKFTDPRWFMGRPSAVDYDATSSGGTNYALSNPKFHEELEKNIEEFLKKNPGVKRSEIPADIVTSSGSGLDPHISPKAAYLQVKRVAKVNGLPEEVVKKLVDKNIEGRFLGLFGEPRVNVLKLNLSLLEEIKKHKK
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: 1FEH_TRIUA
Sequence: MAQAWAFLLPVLVFGSYMTSLFFPTYISGPLCGGDGGGRSLFLCAQAPKDQDPSPAVSTMYKTAFHFQPAKNWMNDPSGPMYFNGFYHEFYQYNPNGPIFGDIVWGHSVSTDLVNWIGLEPALVRDTPSDIDGCWTGSVTILPGGKPVIIYTGGDKDQHQAQNIAFPKNRSDPYLREWIKAANNPVLRPDEPGMNSIEFRDPTTGWIGPDGLWRMAVGGELNGYSAALLYKSEDFLNWTKVDHPLYSHNGSNMWECPDFFAVLPGNNAGLDLSAAIPQGAKHALKMSVDSVDKYMIGVYDLQRDAFVPDNVVDDRRLWLRIDYGTFYASKSFFDSNKNRRIIWGWSRETDSPSDDLEKGWAGLHTIPRTIWLADDGKQLLQWPVEEIESLRTNEISHQGIELNKGDLFEIKEVDAFQADVEIGFELASIDDADPFDPSWLLDPEKHCGEAGASVPGGIGPFGLVILASDNMDEHTEVYFRVYKSEEKYMVLMCSDLRRSSLRPDLEKPAYGGFFEFDLEKERKISLRTLIDRSAVESFGGGGRVCITSRVYPAVLADVGRAHIYAFNNGSATVRVPQLSAWTMRKAQVNVEKGWSAI
What is the function of this protein?
Hydrolyzes inulin-type beta-(2,1)-fructans.  May play a role as a beta-(2,1)-trimmer during graminan biosynthesis (By similarity).
What are the official names of this protein?
Fructan 1-exohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 32 family.
Protein: GCSP_PHOLL
Sequence: MTQTLSQLENQGEFIRRHIGSSAEQQKEMLATVGASSLNDLTQKIVPRDIALPEPPDVGGGATEQQALAELKAIASQNKRYQSYIGMGYAPAVLPPVILRNLLENPGWYTAYTPYQPEVSQGRLESLLNFQQVTIDLTGLDIASASLLDEATAAAEAMAMAKRISKLKNADRFFVADDIHPQTLDVVRTRAETFGFDVIVDKAEKVLELDGVFGVLLQQVGTTGEVHDYADLIAQLKQRKIIVSVAADLMALLLLTAPGKQGADMVFGSAQRFGVPMGYGGPHAAFFASRDEFKRSMPGRIIGVSRDAAGNTALRMAMQTREQHIRREKANSNICTAQVLLANIAAMYAVYHGSKGLKRIAGRIHRLTDILAVGLQKAGFTLRYKTWFDTLTVEVADKAAVLARAEKAEINLRTDTYGAVGITLSEATRRDDVIKLFSVLTGTDDKLDVEALDKELMTESHSIPASMLRSDEILLHPNFNRYHSETDMMRYMHRLERRDLALNQAMIPLGSCTMKLNAAAEMLPISWPEFNELHPFCPPEQAQGYQQMISQLSHWLVQLTGYDVVCMQPNSGAQGEYAGLLAIRRYHESRGEGHRHICLIPSSAHGTNPASAHMAGMTVVVVSCDKEGNIDLVDLREKAEESGNELSCIMVTYPSTHGVYEETIRQVCEIIHQYGGQVYLDGANMNAQVGITAPGFIGADVSHLNLHKTFCIPHGGGGPGMGPIGVKAHLAPFLPGHSVVQMDGLTEQRAVSAAPFGSASILPISWMYIRMMGSQGLKQASQTAILNANYIAARLKNDYDVLYTGHNGYVAHECILDIRPLKEEFGISEMDIAKRLIDYGFHAPTMSFPVAGTLMVEPTESESKVEIDRFVDAMLAIRAEIGKVAKGEWSLEDNPLVNAPHVQAELVSDWSHSYSRETAVFPTLETKANKYWPAVKRLDDVYGDRNLHCSCAPVSDYQ
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: RL34_THISH
Sequence: MKRTFQPSTLKRKRTHGFRARMATRGGRKVLAARRAKGRVRLCP
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: ARGP_SALG2
Sequence: MKRPDYRTLQALDAVIRERGFERAAQKLCITQSAVSQRIKQLENMFGQPLLVRTVPPRPTEQGQKLLALLRQVELLEEEWLGDEQTGSTPLLLSLAVNADSLATWLLPALAPVLADSPIRLNLQVEDETRTQERLRRGEVVGAVSIQHQALPSCLVDKLGALDYLFVASRPFAERYFPNGVTRSSLLKAPAVAFDHLDDMHQAFLQQNFDLPPGSVPCHIVNSSEAFVQLARQGTTCCMIPHLQIEKELESGELINLTPGLLQRRMLYWHRFAPESRMMRKVTDALLEYGHKVLRQD
What is the function of this protein?
Controls the transcription of genes involved in arginine and lysine metabolism.
What are the official names of this protein?
HTH-type transcriptional regulator ArgP.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: END4_SALPB
Sequence: MKYIGAHVSAAGGLANAPARAAEIGATAFALFTKNQRQWRAAPLTPQVIDDFKIACEKYHFSAAQILPHDSYLINLGHPVSEALEKSRDAFLDEMQRCEQLGLTLLNFHPGSHLMQIAQEDCLARIAESINIALAQTEGVTAVIENTAGQGSNLGFEFEQLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPEACEKTFAEFGKIVGFQYLRGMHLNDAKSAFGSRVDRHHSLGEGNIGHDAFRWIMQDGRFDGIPLILETINPDIWAEEIAWLKAQQIAEAMA
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: TMM88_HUMAN
Sequence: MADVPGAQRAVPGDGPEPRDPLDCWACAVLVTAQNLLVAAFNLLLLVLVLGTILLPAVTMLGFGFLCHSQFLRSQAPPCTAHLRDPGFTALLVTGFLLLVPLLVLALASYRRLCLRLRLADCLVPYSRALYRRRRAPQPRQIRASPGSQAVPTSGKVWV
What is the function of this protein?
Inhibits the Wnt/beta-catenin signaling pathway.  Crucial for heart development and acts downstream of GATA factors in the pre-cardiac mesoderm to specify lineage commitment of cardiomyocyte development.
What are the official names of this protein?
Transmembrane protein 88.
What is the protein family that this protein belongs to?
Belongs to the TMEM88 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YCIB_SALPK
Sequence: MKQFLDFLPLVVFFAFYKLYDIYAATSALIVATAIVLIYSWVRYRKIEKMALITFVLVAVFGGLTLFFHNDEFIKWKVTVIYALFAGALLISQWVMKKPLIQRMLGKELALPQQVWSKLNLAWALFFIACGLANIYIAFWLPQNIWVNFKVFGLTALTLIFTLLSGVYIYRHLPQEDKS
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CARB_DESAP
Sequence: MPKDKALKKVMVIGSGPIIIGQAAEFDYAGTQACRALREEGLEVVLINSNPATIMTDANMADRIYIEPLTPEFVAKVISQERPDALLPTLGGQTGLNLAKQVADAGILDQYGVRLLGTPLESIKRAEDREHFKNMCLEIGEPVPESSIISDVDAAVAFARKIGYPVVVRPAYTLGGTGGGVAFSEDELREIAVRGLTMSIIHQVLVEKCVLGWKEIEYEVMRDAAGNCITICSMENIDPMGIHTGDSIVVAPTQTLSDREHQMLRSASLKIIRALGVEGGCNVQFALDPESYDYYVIEVNPRLSRSSALASKATGYPIAKVATKVAVGLTLDEIKNAVTGKTYACFEPALDYVVVKYPRWPFDKFSLANRNLGTQMKSTGEVMAIGRTFEEALLKAVRSLETGVTGMNLPELREWDNDRLRARMARPDDLRLFLVAEALRRGFPVNEIFELTRIDRFFLDKIKNITEAEELVRAARPTDVGTPTGVGAPAGLTPELLRRVKRIGLSDTTIAELVGTTSREVHRLRRELGVEPVYKMVDTCAGEFEATTPYYYSTYEDEDEAEPQAVRKVVVLGSGPIRIGQGIEFDYCSVHSVWALKEQGVKAIIINNNPETVSTDFDTADRLYFEPLVPEDVMNILHKEKPDGVIVQFGGQTAINLARPVEKAGFNILGTSVADIDRAEDRERFDQLVAELGIPRPPGGTGFSVEEAQRIAEQVGFPVLVRPSYVLGGRAMEIVYNSQELLEYMADAVRVTPKHPVLVDKYLLGKELEVDAVCDGETVLVPGIMEHVERAGIHSGDSIAVFPPQTLTPEIKEQLFEYTQQIARALKIRGLVNIQFVLHEGRVFVLEVNPRSSRTVPYLSKVTGIPMVNLATRICLGATLPELGYRGGLYEETRNIAVKAPVFSFAKLLDVDVCLGPEMKSTGEVMGVSKDYALALYKACLSAGYTLPSSGKAVVTIADRDKDEALPLVRSLVNLGFEIVATEGTAAFLRSRAITVEVARKVHEGSPNIVDLIRENRIHLVVNTLTKGKLTTRDGFRIRRAAVEMGVPCLTSLDTARVVIEVMRARQRGETMPLIPLQEYVS
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: RLMH_ALIFM
Sequence: MKIQLIAVGTKMPKWVEEGYKEYSRRFPKDMPLELVEITAGKRGKNADITRILQKEGEAMLAAVPKGNRIVTLDIPGKRWDTEQLAEQLEAWKLDARDVSILIGGPEGLAPACKAAADQSWSLSPLTLPHPLVRVVMAESLYRAWSITANHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LRC38_MOUSE
Sequence: MSLCVAPRHPTGAAAALGLGSLLVLLGPGRACPAGCACTDPHTVDCRDRGLPSVPDPFPLDVRKLLVAGNRIQQIPEDFFIFHGDLVYLDFRNNSLRSLEEGTFSGSGKLAFLDLSYNNLTQLGAGAFRSAGRLVKLSLANNHLAGVHEAAFESLESLQVLELNDNNLRSLNVAALDALPALRTVRLDGNPWLCDCDFAHLFSWIQENTSKLPKGLDAIQCSLPMEDRRVALRELSEASFSECKFSLSLTDLFIIIFSGVAVSIAAIISSFFLATVVQCFQRCAPNKDTEDEDDDEDD
What is the function of this protein?
Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha).  Modulates gating properties by producing a marked shift in the BK channel's voltage dependence of activation in the hyperpolarizing direction, and in the absence of calcium (By similarity).
What are the official names of this protein?
Leucine-rich repeat-containing protein 38, BK channel auxiliary gamma subunit LRRC38.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: GLTB_WHEAT
Sequence: MKTFLVFALLAVAATSAIAQMETRCIPGLERPWQQQPLPPQQTFPQQPLFSQQQQQQLFPQQPSFSQQQPPFWQQQPPFSQQQPILPQQPPFSQQQQLVLPQQPPFSQQQQPVLPPQQSPFPQQQQQHQQLVQQQIPVVQPSILQQLNPCKVFLQQQCSPVAMPQRLARSQMLQQSSCHVMQQQCCQQLPQIPQQSRYEAIRAIIYSIILQEQQQVQGSIQSQQQQPQQLGQCVSQPQQQSQQQLGQQPQQQQLAQGTFLQPHQIAQLEVMTSIALRILPTMCSVNVPLYRTTTSVPFGVGTGVGAY
What is the function of this protein?
Glutenins are high-molecular weight seed storage proteins of wheat endosperm.  Thought to be responsible for the visco-elastic property of wheat dough.
What are the official names of this protein?
Glutenin, low molecular weight subunit 1D1.
What is the protein family that this protein belongs to?
Belongs to the gliadin/glutenin family.
Protein: T23O_RUEPO
Sequence: MSQAYDPSQEGAKMSYAKDMSYGDYLHMDALLATHHPQSDAHDEMLFIIQHQTSELWMRLVLHELRAARALLLAGGDFRPAFKMLTRVARIFDQLNSAWDVLRTMTPSDYTTFRNALGNSSGFQSHQYRLIEYMLGNRNTAMMKVHEHRPELHAMLAAELEQPSLYHVALRALAAKTGASFAPEVYRMDNPHSADAAVQAAWRQVYEDPAKYWDLYELGEKLVDLEDYFRRWRFNHVTTVERVIGFKRGTGGTSGVQYLRRMLEVELFPELWHLRGDL
What is the function of this protein?
Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine.  Catalyzes the oxidative cleavage of the indole moiety.
What are the official names of this protein?
Tryptophan 2,3-dioxygenase, TDO, Tryptamin 2,3-dioxygenase, Tryptophan oxygenase, TO, TRPO, Tryptophan pyrrolase, Tryptophanase.
What is the protein family that this protein belongs to?
Belongs to the tryptophan 2,3-dioxygenase family.
Protein: Y1730_ALIFM
Sequence: MKIQSIFAASFCLLSSISAHAAIQLTVPDEVELILVDNQEVKLESSFFSTTSTLDLENGKHQIVFRYNPVFKQGKDNIIVSSDIIVSTFSAEDKEISFKFPTYNSPEKAKAFNRDLNWELIDKNNNSIPFAQSQLIYNGMQVGRNIQFEVAKFNTTEHPAAFKEGMLTVTHKEIKNEQGENTAEQMLHYWYEKADQATKERFLKSITNK
What are the official names of this protein?
UPF0319 protein VFMJ11_1730.
What is the protein family that this protein belongs to?
Belongs to the UPF0319 family.
Protein: AACC7_STREY
Sequence: MDELALLKRSDGPVTRTRLARDLTALGLGDGDTVMFHTRMSAVGYVAGGPETVIGALRDVVGERGTLMVTCGWNDAPPYDFTDWPQTWQDARRAEHPAYDPVLSEADHNNGRLPEALRRRPGAVRSRHPDASFAALGAAATALTADHPWDDPHGPDSPLARLVAMGGRVLLLGAPLEALTLLHHAEALADAPGKRFVDYEQPILVDGERVWRRFHDIDSEDGAFDYSALVPEGTEAFEIIGRDMRAAGIGRRGTVGAADSHLFEARDVVDFGVAWMEEKLGRERGPGG
What is the function of this protein?
Resistance to paromomycin.
What are the official names of this protein?
Aminoglycoside N(3)-acetyltransferase VII, ACC(3)-VII, Aminocyclitol 3-N-acetyltransferase type VII.
What is the protein family that this protein belongs to?
Belongs to the antibiotic N-acetyltransferase family.
Protein: PDRP_RICFE
Sequence: MTKLIIHLVSDSSVQTAKYAANSAFAQFTSIKPKLYHWPMIRNLELLNEVLSKIESKHGLVLYTIADQELRKALTKFCYELKIPCISVIGKIIKEISVFSGIEIEKEQNYNYKFDKTYFDTLNAIDYAIRHDDGQMLNELSEADIILIGPSRTSKTPTSVFLAYNGLKAANIPYVYNCPFPDFIEKDIDLLVVGLVINPNRLIEIREARLNLLQINENKSYTDFNIVQKECLEVRKICDQRNWPVIDVSTRSIEETAALIMRIYYNRKNKYNK
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: RECX_STRPN
Sequence: MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEEELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDINENIVSQVIANLKEEKWINDSQYAYAIINANQLSGDKGPYVLTQKLAQKGISKSTIEEILNDFDFSEVAQRVANKLLKKYEGKLPARALQDKIIQNLTNKGFSYFDAKIAFDELDSQVDEETTQELIFKELDKQYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AGL8_SOLLC
Sequence: MGRGRVQLKRIENKINRQVTFSKRRSGLLKKAHEISVLCDAEVGLIVFSTKGKLFEYANDSCMERILERYERYSFAEKQLVPTDHTSPVSWTLEHRKLKARLEVLQRNQKHYVGEDLESLSMKELQNLEHQLDSALKHIRSRKNQLMHESISVLQKKDRALQEQNNQLSKKVKEREKSAQQISGINSSSLFAHTDFYLGTYQSTNVIDNGKWKEVVLHSSKVQLIIL
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
Agamous-like MADS-box protein AGL8 homolog, TM4.
What are the subcellular locations of this protein?
Nucleus.
Protein: FYNA_DANRE
Sequence: MGCVQCKDKEATKLTDERETSVSQHAGYRYGSDPTPQHYPSFGVTAIPNYNNFHAPVSQGVTVFGGVNSSSHSGTLRSRGGTGVTLFVALYDYEARSEDDLSFRKGEKFQILNSTEGDWWEARSLTTGGTGYIPSNYVAPVDSIQAEDWYFGKLGRKDAERQLLSNGNPRGTFLIRESETTKGAYSLSIQDWDETKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVHHYSARAAGLCCRLIVPCHKGMPRLADLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAVKTLKPGTMSPESFLEEAQIMKKLRHDKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKDGEGRGLKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGDSLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPSSLHELMLQCWKRDPEERPTFEYLQAFLEDYFTATEPQYQPGDNL
What is the function of this protein?
Tyrosine-protein kinase implicated in the control of cell growth.  Plays a role in the regulation of intracellular calcium levels.  Required in brain development and mature brain function with important roles in the regulation of axon growth, axon guidance, and neurite extension.  Role in cntn1-mediated signaling (By similarity).  Required for convergent extension cell movements during gastrulation, acting with yes via rhoa.  May be required for epiboly to occur, possibly through its effects in calcium signaling.
What are the official names of this protein?
Tyrosine-protein kinase fyna, Proto-oncogene c-Fyna.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Transiently expressed in the nucleus at mid-blastula stage (3.3 hpf) in a large subset of cells. Nuclear localization is not observed from late blastula stage onward.
Protein: LUZP2_MOUSE
Sequence: MKFNAAHYLLPLLPALVLSTRQDYEELEKQLKEVFKERSTVLRQLTKTSRELDGIKVNLQSLKNDEQSSKTDVQKLLELGQRQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGSKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTELEQKLAVAKNELEKAALDRESQMKAMKETVQLCLSSVFRDQPPPLSLMPSNPTQMLHPPRTVASRIPEARTKSKPQPSSPGHHDSSQVQATKEESRRPSVCGPQDEGSSCLVKHEEGPQSNSTAESELTTQKLQMPICSECEEKKGPENPSASFDGTPAREEKLL
What are the official names of this protein?
Leucine zipper protein 2.
What are the subcellular locations of this protein?
Secreted.
Protein: AIM21_YEAS2
Sequence: MSSEVTPKVPERPSRRKTSELFPLSGSESGDIEANSEPPTPAGTPNVPTRRPILKAKTMTSFESGMDQESLPKVPLQRPVRRSTTEELNNVMNNTSKELEEIESLISKHNIHNVSRKKSPTSVEEGKVAAIHQNGQRSASDNKTSTNPSPLEKNEHEGAEGNEFAISPSNLVNKSNNEVTEHSDSEDLTEKQKVHAALDNEAGDRSHFEEKLIPGDMKVQVDVSKDVEEGSLNALPPSGITESDDKAEKFTKHPESSLEELQKHQEQQEEKIFQNPTDEESTTSLNEKQEGKDNMEVNSQPQGPSDTETVIAATSSNVPSQIASEEENDVPVIPRSRPKKDFEAHVQKEELPNTQEKRVSEECDSTLISTEEESKIPKIPSERPKRRAPPPVPKKPSSRIAAFQEMLQKQQQQDLHNNGNSSATTASADIAKKHTDSSITSDTTKADFTSKLNGLFALPGMVNPGQLPPSLEKKLSSPDTESKLGPQDQSQAKTGPLGGTRRGRGPRGRKLPSKVASVEKIEEDDNTNKIEIFNNWNVSSSFSKEKVLIDTTPGEQAERALDEKSKSIPEEQREQSPNKMEAALCPFELDEKEKLPANAESDPLSQLPQTNTVGNRKAISEESLSPSEAIANRDQNDTTEIQEQQMEDQMEVDMERELSGGYEDVDSALHSEEASFHSL
What is the function of this protein?
Involved in mitochondrial migration along actin filaments.
What are the official names of this protein?
Altered inheritance of mitochondria protein 21.
What is the protein family that this protein belongs to?
Belongs to the AIM21 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, actin patch. Note=Cortical actin patches. Localizes at the shmoo tip.
Protein: MNME_HAEIE
Sequence: MKETIVAQATAPGRGGIGILRVSGPLATEVAQAILGKCPKPRMADYLPFKDADGTILDQGIALYFKSPNSFTGEDVLELQGHGGQVVLDLLLKRILQIDGIRLARPGEFSEQAFLNDKLDLAQAEAIADLIDATSEQAARSALKSLQGEFSKKVNELVDSVIYLRTYVEASIDFPDEEIDFLADGKIEANLRGIINQLENVRSEAKQGSILREGMKVVIAGRPNAGKSSLLNALAGREAAIVTDIAGTTRDVLREHIHIDGMPLHIIDTAGLRDATDEVERIGISRAWTEIEQADRIILMLDSSDPESADLSKVRSEFLAKLPSTLPVTIVRNKIDLNGEQASESEEGGYQIISLSAQTHDGVKLLREHLKQAMGFQTGIEGGFLARRRHLDALEKAAEHLQIGLVQLTEFHAGELLAEELRLVQSYLSEITGQFTSDDLLGNIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPLT_SHIBS
Sequence: MSESVHTNTSLWSKGMKAVIVAQFLSAFGDNALLFATLALLKAQFYPEWSQPILQMVFVGAYILFAPFVGQVADSFAKGRVMMFANGLKLLGAASICFGINPFLGYTLVGVGAAAYSPAKYGILGELTTGSKLVKANGLMEASTIAAILLGSVAGGVLADWHVLVALAACALAYGGAVVANIYIPKLAAARPGQSWNLINMTRSFLNACTSLWRNGETRFSLVGTSLFWGAGVTLRFLLVLWVPVALGITDNSTPTYLNAMVAIGIVVGAGAAAKLVTLETVSRCMPAGILIGVVVLIFSLQHELLPAYALLMLIGVMGGFFVVPLNALLQERGKKSVGAGNAIAVQNLGENSAMLLMLGIYSLAVMVGIPVVPIGIGFGALFALAITALWIWQRRH
What is the function of this protein?
Catalyzes the facilitated diffusion of 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) into the cell.
What are the official names of this protein?
Lysophospholipid transporter LplT.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CLCN5_RAT
Sequence: MAMWQGAMDNRGFHQGSFSSFQSSSSDEDLMDIPGTAMDFSMRDDVPPLDREIEGNKSYNGGGIGSSNRIMDFLEEPIPGVGTYDDFNTIDWVREKSRDRDRHREITNKSKESTWALIHSVSDAFSGWLLMLLIGLLSGSLAGLIDISAHWMTDLKEGICTGGFWFNHEHCCWNSEHVTFEDRDKCPEWNSWSQLIISTDQGAFAYIVNYFMYVLWALLFAFLAVSLVKAFAPYACGSGIPEIKTILSGFIIRGYLGKWTLVIKTITLVLAVSSGLSLGKEGPLVHVACCCGNILCHCFNKYRKNEAKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFTLRSINPFGNSRLVLFYVEFHTPWHLFELVPFIVLGIFGGLWGALFIRTNIAWCRKRKTTQLGKYPVVEVLIVTAITAILAFPNEYTRMSTSELISELFNDCGLLDSSKLCDYENHFNTSKGGELPDRPAGVGVYSAMWQLALTLILKIVITIFTFGMKIPSGLFIPSMAVGAIAGRLLGVGMEQLAYYHHDWGIFNSWCSQGADCITPGLYAMVGAAACLGGVTRMTVSLVVIMFELTGGLEYIVPLMAAAMTSKWVADALGREGIYDAHIRLNGYPFLEAKEEFAHKTLAMDVMKPRRNDPLLTVLTQDSMTVEDVETIISETTYSGFPVVVSRESQRLVGFVLRRDLIISIENARKKQDGVVSTSIIYFTEHSPPMPPYTPPTLKLRNILDLSPFTVTDLTPMEIVVDIFRKLGLRQCLVTHNGRLLGIITKKDVLKHIAQMANQDPESILFN
What is the function of this protein?
Proton-coupled chloride transporter.  Functions as antiport system and exchanges chloride ions against protons.  Important for normal acidification of the endosome lumen.  May play an important role in renal tubular function (By similarity).  The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons.  The absence of conserved gating glutamate residues is typical for family members that function as channels (Probable).
What are the official names of this protein?
H(+)/Cl(-) exchange transporter 5, Chloride channel protein 5, ClC-5, Chloride transporter ClC-5.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClC-5/CLCN5 subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: CFBA_METMP
Sequence: MEALVLVGHGSRLPHSKNVVMEVAEKIKARNIYDIVEVGMMEFNEPTIPQTIKKVIDAGAKKVIVTPVFLAPGNHTERDIPKILGIYEGDDEGGHHHHHDHEHHHHHHDTTAVEIPEGVELVYRKPMGADDRIIDIVLDRANGL
What is the function of this protein?
Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis.  Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation.  Catalyzes the insertion of Ni(2+) into sirohydrochlorin to yield Ni-sirohydrochlorin.
What are the official names of this protein?
Sirohydrochlorin cobaltochelatase, CbiXS, Sirohydrochlorin nickelchelatase.
What is the protein family that this protein belongs to?
Belongs to the CbiX family. CbiXS subfamily.
Protein: YAJG_ECOL6
Sequence: MFKKILFPLVALFMLAGCAKPPTTIEVSPTITLPQQDPSLMGVTVSINGADQRTDQALAKVTRDNQIVTLTASRDLRFLLQEVLEKQMTARGYMVGPNGPVNLQIIVSQLYADVSQGNVRYNIATKADIAIIATAQNGNKMTKNYRASYNVEGAFQASNKNIADAVNSVLTDTIADMSQDTSIHEFIKQNAR
What are the official names of this protein?
Uncharacterized lipoprotein YajG.
What is the protein family that this protein belongs to?
To H.influenzae HI_0162.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: R126A_XENLA
Sequence: MAEALPKAGRYFCHSCTAEITPRLPEYTCPRCDSGFIEELPETSRNSENNSSNNSRTDQNRPSFENLESAQFTLPSGYGQVTFGIFNEGLDFPIFGTSGPVEETRDGESRREHQSRQRYGARQPRARLSTRRAAGRNEGVPTLEGIIQQLVNGIIAPTAMSNLGVGPWGVLHSNPMDYAWGANGLDTIITQLLNQFENTGPPPADNEKIQALPTIQITEEHVGSGLECPVCKEDYTVGECVRQLPCNHLFHNDCIIPWLEQHDTCPVCRKSLSGQNTATNPPGLSEMTFSSSSTSSSSSTSPTDENNSANNS
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates ubiquitination oF target proteins.  Depending on the associated E2 ligase, mediates 'Lys-48'- and 'Lys-63'-linked polyubiquitination of substrates.  Part of a BAG6-dependent quality control process ensuring that proteins of the secretory pathway that are mislocalized to the cytosol are degraded by the proteasome.  Probably acts by providing the ubiquitin ligase activity associated with the BAG6 complex and be responsible for ubiquitination of the hydrophobic mislocalized proteins and their targeting to the proteasome.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF126-A, RING finger protein 126-A, RING-type E3 ubiquitin transferase RNF126-A.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.