PharMolix/UniProtQA huggingface dataset:
Protein: ATP8_FELCA
Sequence: MPQLDTSTWSITIMSMIMTLFIVFQLKISKYLYPSNPEPKSMTTLKQRNPWEKKWTKIYSPLSLPQQ
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: SYR_PARUW
Sequence: MNTLLSVLANLFQQATANAFPDLSVLDPNFQPEITPSTQEKFGHYQFNSAMKLAKLLKKNPRQVAEAIVNQLTDSLPPLSKIEIAGPGFINMTFSTDFLSKNLDILLRDAHFGIPFPEKPEKIIIDFSSPNVAKEMHVGHLRSTVIGDSLARLFEFLGHHVIRLNHLGDWGTAFGMLIAYMKEEAPNVLSGEQKTDLTHLVSWYRSSKKKFDEEPEFKRRAQLEVVALQQGEQKAREAWQMICEISQKAYQEIYQLLDVKIIDRGESFYNPFLPNIVSDLEKKGLVKISDGAKCIFLEGFQNREGENLPLMIQKSDGGYNYDTTDMAAIYHRIYHEKGDRLIYITDAGQATHFQMIFKAAEKAKYLDTTQIRVDHVPFGLVLGTDGKKFRTRSGETEKLIDLLRTAINCADKILSEKNPEMEESERRHLAKSLGIGAIKYADLSCNRVGDYTFSYDRMLRFEGNTAAFLMYAYVRIAGIKRRLKANLPAVLENTHINLEHSTEIELGLHILRFHETLNLMANDLLPNRLTDYLYTLAEKFNAFFRDCRVEGTPQQNTRLLLCEATAKVLKQGLTILGLTTVDKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_VEREI
Sequence: MKTTELRAKDVAGIEAEIKALQKAHFSLRMQKATQQLSNTSTLRTTRRAIARAKTILAQKQAAH
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: NRDR_RUMCH
Sequence: MKCPFCGFIEDKVIDSRPTDEGSSIRRRRECTKCSRRFTTYEKVESLPLMVIKKDKSRQPFNREKLMNGLLRACEKRPISINDLEKMVENIEAQLHNSLQREVTTVDIGEIVMSKLKTMDEVAYVRFASVYRQFKDINTFMDELRKLLREEKIE
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: RSMG_SULDN
Sequence: MNLKTALLELDTELPDTFFHHIQKFKEHLFKWNKIHNLTGAKDENTIDEFIYDAIYPITFLPKCKNLLDIGTGAGFPGLILAMGLPETEVTLVEPLAKRASFLQFIKADLGLSNVKVVQKRVQDMPSEIFEIVTSRAVIDTNMLLELSKGFRNKDSKLLFFKGERVYDEVNKDLKYKIIKRENRHYLLIGETL
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_GLUOX
Sequence: MAEITAALVRELREATGAGMMDCKKALTEAAGDMEAAIDWLRTKGLSQAAKKSGRTTAEGLVGVASAKNRAAMVEVNAETDFVGRNEAFQAFVEQVAHVALEVGDDLDAIKAGKVPSGRTVADELTHLIATIGENMAIRRAKVLSVESGVVASYVHSALRPGIGKIGVLAALEAPSESDALLTLGRQIGMHVAATRPAALDVASVDPEALERERAVLIEQARESGKPEAIIEKMVEGRIRKFYEEVVLLEQVWVLDGESRVAKVVEKAGAKLVGFERFQLGEGIEKEESDFAAEVAAAAGTK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REV_HV1Z8
Sequence: PPPSPEGTRQARRNRRRRWRARQRQIHSISERILSTLLGRSPEPVPLQLPPLERLNLNCNEDCGTSGTQGVGSHQISVESPAVLDSGTEE
What is the function of this protein?
Escorts unspliced or incompletely spliced viral pre-mRNAs (late transcripts) out of the nucleus of infected cells.  These pre-mRNAs carry a recognition sequence called Rev responsive element (RRE) located in the env gene, that is not present in fully spliced viral mRNAs (early transcripts).  This function is essential since most viral proteins are translated from unspliced or partially spliced pre-mRNAs which cannot exit the nucleus by the pathway used by fully processed cellular mRNAs.  Rev itself is translated from a fully spliced mRNA that readily exits the nucleus.  Rev's nuclear localization signal (NLS) binds directly to KPNB1/Importin beta-1 without previous binding to KPNA1/Importin alpha-1.  KPNB1 binds to the GDP bound form of RAN (Ran-GDP) and targets Rev to the nucleus.  In the nucleus, the conversion from Ran-GDP to Ran-GTP dissociates Rev from KPNB1 and allows Rev's binding to the RRE in viral pre-mRNAs.  Rev multimerization on the RRE via cooperative assembly exposes its nuclear export signal (NES) to the surface.  Rev can then form a complex with XPO1/CRM1 and Ran-GTP, leading to nuclear export of the complex.  Conversion from Ran-GTP to Ran-GDP mediates dissociation of the Rev/RRE/XPO1/RAN complex, so that Rev can return to the nucleus for a subsequent round of export.  Beside KPNB1, also seems to interact with TNPO1/Transportin-1, RANBP5/IPO5 and IPO7/RANBP7 for nuclear import.  The nucleoporin-like HRB/RIP is an essential cofactor that probably indirectly interacts with Rev to release HIV RNAs from the perinuclear region to the cytoplasm (By similarity).
What are the official names of this protein?
Protein Rev, ART/TRS, Anti-repression transactivator, Regulator of expression of viral proteins.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Note=The presence of both nuclear import and nuclear export signals leads to continuous shuttling between the nucleus and cytoplasm.
Protein: Y773_CLOAB
Sequence: MIKLEKVSFTYKNRAALCDVNVDINEGEAVAIIGPNGSGKSTFLKVLNGILFPSSGRYVFDNNEINENTLKNNKFLKLFHKRVGFVFQNSDAQLFCSTVFDEVAFGIMQMGLEGEEVDKRVRDCLKLLNIEKLKEEHPYNLSGGEKKRVAIASVLAMNPEVITLDEPMNAIDPKGKRFLKELLIDLNKSGKTIICATHDFEYIEGVFNRAVVFSENHKIIRDDRYENIISDREFLMECNII
What is the function of this protein?
Probably part of an ABC transporter complex.  Responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Putative ABC transporter ATP-binding protein CA_C0773.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PUR7_RICCK
Sequence: MKKKLYEGSSKILYSAEEDFLLIMAFSDKAILETGKTVDISGKGVLNNNISSFLMDKLEMIGIANHFIEKINMREQLIQYVEVFPIQVIISSVACGRFVKEFGLDEGYVFDKPIMDFKVRSREFKYPIVNEYQILNFGWLTRDEITAVKEQALHIYDFLSGLFIGVGIRLVECKLEFGRVFNGEESIIMLTDEISPDNCRLWHINSNEKLGFELLENEPSKVFESYQLIAERLKEK
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: RS14_SHIF8
Sequence: MAKQSMKAREVKRVALADKYFAKRAELKAIISDVNASDEDRWNAVLKLQTLPRDSSPSRQRNRCRQTGRPHGFLRKFGLSRIKVREAAMRGEIPGLKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: YR866_MIMIV
Sequence: MSREIIIQTNNATIYTTYSTISNIKLFTDNIQPETRVIYLNIDGLIVDGILNNIRQGLNALTNYENYDFSMCTNRNCALINIGGRKFYLPRSLLSDFDFFNEILSETEFDHNQNIIDRSPYVFDKIIDLIDNDDISNTKYFSQDVLSDLQFYKYKKIIGKLFIDNDFAYFKINGNIYDATLECNYDVDRHQVDLEDNDFDNYTIFTNSPTSNDPTHCVLWFDRYMEKLDIESIAEKIRLNDTPLSEYYSHSLEKFDPNYESPDSIEPYYVTTYPNGHTVIYFLFPNVFYPLIYIPKNIGIISHKLVYKERYQPSIIKESYTKYFPKTSIVKIDLNDVLKVMDKNFHDKILLINELYIYSEKVNYTYAEIINNGKIVCRSTLSKCKDSFTINLFNSTYNCIAYNISDNDNSKLVLYSDKETEHNIILKFEYS
What are the official names of this protein?
Uncharacterized protein R866.
Protein: AGR2_DANRE
Sequence: MLKGLLSVLLVMVALSSALGKPEKTTPKKEKEKRVPQTLSRGWGDQLIWAQTYEEALFWSRSKNKPLMVIFHLEDCPHSQALKKAFAEDKEIQKLADEDFVILNLVYETTDKHLSPDGQYVPRIIFVDPSMTVRADITGRYSNRMYAYEPADMKLLLSNMQRALKFLKTEL
What are the official names of this protein?
Anterior gradient protein 2 homolog, Zagr2.
What is the protein family that this protein belongs to?
Belongs to the AGR family.
What are the subcellular locations of this protein?
Secreted. Endoplasmic reticulum.
Protein: CSRA_SHEPC
Sequence: MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHREEIYQRIQSEKSGSPSEGGNF
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H12_ARATH
Sequence: MSIEEENVPTTVDSGAADTTVKSPEKKPAAKGGKSKKTTTAKATKKPVKAAAPTKKKTTSSHPTYEEMIKDAIVTLKERTGSSQYAIQKFIEEKHKSLPPTFRKLLLVNLKRLVASEKLVKVKASFKIPSARSAATPKPAAPVKKKATVVAKPKGKVAAAVAPAKAKAAAKGTKKPAAKVVAKAKVTAKPKAKVTAAKPKSKSVAAVSKTKAVAAKPKAKERPAKASRTSTRTSPGKKVAAPAKKVAVTKKAPAKSVKVKSPAKRASTRKAKK
What is the function of this protein?
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.
What are the official names of this protein?
Histone H1.2.
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: DEFB3_RAT
Sequence: MRIHYLLFSFLLVLLSPLSAFSKKVYNAVSCMTNGGICWLKCSGTFREIGSCGTRQLKCCKKK
What is the function of this protein?
Has bactericidal activity.
What are the official names of this protein?
Beta-defensin 3, BD-3, Defensin, beta 3.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MURC_CROS8
Sequence: MNTQQLAKLRSIVPEMRRVRHIHFVGIGGAGMGGIAEVLANEGYQISGSDLAPNAVTQQLTALGATIYFNHRPENVLDASVVVVSSAISADNPEIVAAHEARIPVIRRAEMLAELMRFRHGIAVAGTHGKTTTTAMVSSIYAEAGLDPTFVNGGLVKAAGTHARLGNSRYLIAEADESDASFLHLQPMVAIVTNIEADHMDTYHGDFENLKQTFINFLHNLPFYGRAVMCVDDPVIRELLPRVGRQITTYGFSEDADVRVENYRQTGAQGHFTLVRQDKPELHVTLNAPGRHNALNAAAAVSVATEEGIEDDAILRALESFQGTGRRFDFLGEFPLANVNGKSGTAMLVDDYGHHPTEVDATVRAARAGWPEKNLVMIFQPHRYTRTRDLYDDFANVLSQVDVLLMLDVYPAGEAPIPGADSRSLCRTIRARGKVDPILVSDPAQVAAMLAPVLSGNDLILVQGAGNIGKIARQLAEAKLQPEENAHG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_BORAP
Sequence: MNTVFNGKDFANKYYLMLKEFLKERNLRNKITLKVVLANDEPASKLYVSIKNRVAKEIGLNVEVIKLSANSVQSDILEVIDRENKNLSTDGIIVQLPLLKGMDLNSILNGIVSSKDVDGLSFVNLGKMILGDKKGFVPCTALAVLKILRDEGIKTSGKTVVVVGRSPLVGRPISILLSSKPHDATVIACHSKSIYLDVYLRQADIIISAVGKPKLIDKSMLCGKPYVIDIGISEIETDAGKILSGDTDFDNIKDCVKFITPVKGGIGPVTVLMLMFNTIKAHLINNNMFDVLDRLEKLVEV
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: HM35_CAEEL
Sequence: MTDHPPIDTSSYFDCYQQHQLPLQYTFTSSSNSNTSNSSTSPSHISDQFSSSGGPPYELSSHILTPSSVIPTPSPSVASASISSPTIPAFGCTMSEYSMEQMEAISTSLFQARDGDRLVAFFKQLESLYGPNAVDHLRSEAIIVAYTYALYHSNEFETLFHLLSNRHFQQRHYNDLQDIWHHARYKESQLKRGKELNPVEKYRLRRKFPAPKTIWDGEEIVYSFKDSSRKFLKQFFRNVSEYPTQEQKREISRATGLKIVQISNWFKNRRQRDKSNNSAKCSPPSSSSSTNGGSDFLPIITPQSFNLAAAPFNMNMIYGTLRDSQSDNDQFTFNP
What is the function of this protein?
Probable transcription factor required for differentiation and migration of neuronal cells, such as RID and CAN neurons (PubMed:2361334, PubMed:15282156).  Specifically, plays a role in the terminal differentiation of RID peptidergic neurons (PubMed:27855782).  Also required for CAN neuron axon guidance (PubMed:15282156).
What are the official names of this protein?
Homeobox protein unc-39, Homeobox protein ceh-35, Uncoordinated protein 39.
What is the protein family that this protein belongs to?
Belongs to the SIX/Sine oculis homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EFTS_XANOP
Sequence: MEITASLVKELRERTGAGMMECKKALVENAGDIDAAAEWLRKSGLAKADKKADRVAAEGRIATAQAGGKAVLVEVNSETDFVAKDENFLAFTEVVANAALNSDAADAEALKSVKLDSGETIEERRAAVIAKVGENLQVRRLVRIDSANNVAAYVHGGRIGVLVELKGGDIELARGIAMHIAAMNPPHVKASDVPAEFVAKEKEIELAKMSEKDKAKPADILEKIISGKISKIVNEVTLYGQPYVLNTDQTVEQAVKAAGAEVIRFQRLAVGEGIEKVVEDYAAEVMKQAGLA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE1_MYCSJ
Sequence: MTGLSRERYAALYGPTTGDRIRLADTDLVIEITEDRSGGTGLAGDEAVFGGGKVLRESMGQSRATRADGAPDTVITGAVILDHWGIIKADIGIRDGRIVAIGKAGNPDIMDGVHPDLVVGPSTEIIAGNGRILTAGAIDCHVHLICPQIMEEALGGGITTIVAGGTGPAEGSKATTVTPGAWHLARMLEALDTWPLNVVLLGKGNTVSAEAMWEQLRGGAAGFKLHEDWGTTPAAIDACLTVADAAGVQVNIHTDTLNEMAFVEDTLAAIKGRSIHAYHTEGAGGGHAPDIITVASHPNVLPSSTNPTRPHTVNTLDEHLDMLMVCHHLNPSVPEDLAFAESRIRPSTIAAEDLLHDIGAISMIGSDAQAMGRIGEVVLRTWQTAHVMKRRRGALEGDGRADNNRARRYVAKYTICPAVAHGLDGEIGSVEVGKLADLVLWEPAFFGVRPHAVIKGGMIAWAAMGDANASIPTPQPVLPRPMFGAAPAAAAATSVHFVSPQAIEDGLADRIDVRRSLIAVADCRHVGKAQMPLNDAMPRIEVDPDTFTVRIDGDVWQEQPAAELPMAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PKHM1_RAT
Sequence: MLSVENGLDPRAAIQVIKKKLVGSVKALQKQHVSLDTVVTSEDGDANTMCSALEAVFIHGLHAKYIRAEAGGKRKKHTHQKPLPQPVFWPLLKAVTHKHIISDLEHLVFINTDVGRCRAWLRLALNDGLMECYLKLLLQEPARLCEYYQPTALLRDAEEAEFLLSFLQGLTSLSFELSYKSAILNEWTLTPLSLSGLCPLSELDPLTVSGAELQRKESLDSISHSSGSEDIEVQHSGHKIRRDRKLTASSLSLDTASSSQLSCSLNSDSCLLQENGPKSPDHSEEPMSYDSDLGTANADDSDRSLQEVLSEFSKAQVNSAPSSGPSQESDTPMFQTPLSLHSLANSTHLLFEGSEEPFPAHTSSGTSSGHKHQPQESPDMQPLGTAQAGPAGSTSDQQPSSPVAGAADQGSEPWKALEYGRVGPKLVVSSPTSPKGKSWISEDDFCRPPKEHALKNTSDLCISPLQGTPELRTALHGPFSQGPRKSCSLGALDKACVSSLDYRNAQTAPSPAVTQDHKNFCVVHRRQMGLSNPFRGLMKLGTVARRGAMGIWKEFFCELSPLELRLYLSDEERTCVESCSLLRCEAVGPAHSDGRFELVFSGKKLALRASSQDEAEDWLDRVREALQKVRPQQEEEWVNIQYPDQAEDSPEAPPDNLPPYSALLPEHAGAQGIQPNWTSAQVPEPDAIKESLLYLYADRTWIPYIFSLSLESLKCFRVRNNEKMLSDSHGVETIRDILPDTSLGGPAFFKIITAKAVLKLQAKNTEEAAHWRDLVRKVLASYLESVQEAVTLAGSLDENCQEVLKFATRENGFLLQYLVAIPTEKGLDSQGCFCAGCSRQIGFSFVRPKLCAFSGLYYCDFCHQDDASVIPARIIHNWDLTKRPVCRQALKFLAQIRAQPLINLQLVNASLYEHVERMHLIGRSREQLKLLGDYLGLCRSGALKELSKRLSHRNYLLESPHKFSVADLQQIAEGVYEGFLKALIEFASQHVYHCDLCTQRGFICQICHHQDIIFPFEFDTTVRCAECRTVFHQSCQAVVRKGCPRCARRRKYQEQNTVS
What is the function of this protein?
Acts as a multivalent adapter protein that regulates Rab7-dependent and HOPS complex-dependent fusion events in the endolysosomal system and couples autophagic and the endocytic trafficking pathways.  Acts as a dual effector of RAB7A and ARL8B that simultaneously binds these GTPases, bringing about clustering and fusion of late endosomes and lysosomes.  Required for late stages of endolysosomal maturation, facilitating both endocytosis-mediated degradation of growth factor receptors and autophagosome clearance.  Interaction with Arl8b is a crucial factor in the terminal maturation of autophagosomes and to mediate autophagosome-lysosome fusion (By similarity).  Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts (PubMed:17404618).  May be involved in negative regulation of endocytic transport from early endosome to late endosome/lysosome implicating its association with Rab7.  May have a role in sialyl-lex-mediated transduction of apoptotic signals (By similarity).  Involved in bone resorption (By similarity).
What are the official names of this protein?
Pleckstrin homology domain-containing family M member 1, PH domain-containing family M member 1.
What are the subcellular locations of this protein?
Autolysosome membrane. Endosome membrane. Late endosome membrane. Lysosome membrane. Note=In case of infection colocalizes with Salmonella typhimurium sifA in proximity of Salmonella-containing vacuole (SCV).
Protein: DAPF_BACCN
Sequence: MSQFSFTKMHGLGNSYIYVNMFEEHIPEEELALVAEKVSNRNTGIGADGMILICPSEVAPVKMRMFNNDGSEGKSCGNGLRCVAKYAYEHKLVEETIFTIETLAGIVTAEVTVENDIVTLVKIDMGAPRLTRAELPMLGEGETPFIREDFLFHNQRYAFTAVSMGNPHAVIFVDDVEKAPLTTLGPVLENHEMFPERVNVEFIEILNETEMNFRVWERGSGVTQACGTGACASVVAAILNGKMERGKEITVHLAGGDLMITWTEEGTVMMKGPAEVICHGVYEYKIEA
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIFH_METHJ
Sequence: MKQIALYGKGGIGKSTTSANLSAALVNRGLSVMQIGCDPKRDSTRMLMKGILIPTVLDLIRERGEENLTLDDVVFTGYKGVRCVEAGGPEPGVGCAGRGIIATFQLLERLSAFDEDIIVYDVLGDVVCGGFAMPMRKGYAQEIYLVTSGELMSLYAANNICKAISRISQNVRQVCRLGGVICNSRNLPDEEKLVGAFASEVGSKIIAYIPRSGLVQYAELNNQTVIEFAPDSSLSATYQSLAEEIMTNTDFVIPKPLEIEELEKLARSYLPTIDHQGINH
What is the function of this protein?
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
What are the official names of this protein?
Nitrogenase iron protein, Nitrogenase Fe protein, Nitrogenase component II, Nitrogenase reductase.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: FLGI_SALPB
Sequence: MFKALAGIVLALVATLAHAERIRDLTSVQGVRENSLIGYGLVVGLDGTGDQTTQTPFTTQTLNNMLSQLGITVPTGTNMQLKNVAAVMVTASYPPFARQGQTIDVVVSSMGNAKSLRGGTLLMTPLKGVDSQVYALAQGNILVGGAGASAGGSSVQVNQLNGGRITNGAIIERELPTQFGAGNTINLQLNDEDFTMAQQITDAINRARGYGSATALDARTVQVRVPSGNSSQVRFLADIQNMEVNVTPQDAKVVINSRTGSVVMNREVTLDSCAVAQGNLSVTVNRQLNVNQPNTPFGGGQTVVTPQTQIDLRQSGGSLQSVRSSANLNSVVRALNALGATPMDLMSILQSMQSAGCLRAKLEII
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: FCTA_ECOLC
Sequence: MSTPLQGIKVLDFTGVQSGPSCTQMLAWFGADVIKIERPGVGDVTRHQLRDIPDIDALYFTMLNSNKRSIELNTKTAEGKEVMEKLIREADILVENFHPGAIDHMGFTWEHIQEINPRLIFGSIKGFDECSPYVNVKAYENVAQAAGGAASTTGFWDGPPLVSAAALGDSNTGMHLLIGLLAALLHREKTGRGQRVTMSMQDAVLNLCRVKLRDQQRLDKLGYLEEYPQYPNGTFGDAVPRGGNAGGGGQPGWILKCKGWETDPNAYIYFTIQEQNWENTCKAIGKPEWITDPAYSTAHARQPHIFDIFAEIEKYTVTIDKHEAVAYLTQFDIPCAPVLSMKEISLDPSLRQSGSVVEVEQPLRGKYLTVGCPMKFSAFTPDIKAAPLLGEHTAAVLQELGYSDDEIAAMKQNHAI
What is the function of this protein?
Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR).  Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate (By similarity).
What are the official names of this protein?
Formyl-CoA:oxalate CoA-transferase, FCOCT, Formyl-coenzyme A transferase, Formyl-CoA transferase.
What is the protein family that this protein belongs to?
Belongs to the CoA-transferase III family. Frc subfamily.
Protein: RS14_STRM5
Sequence: MAKTSMVNRDIKRKKLAEKYAVKRAALKKIVSSQDATYEEKIEAATKLSKLPRDSSPSRHRSRCELSGRPRGVYSKFGLGRNKLREATMRGDVPGLRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: RPIA_SYNSC
Sequence: MADLQTQMKQAVADAAVEQIKDGMVLGLGSGSTAALMIQGLGAKLASGELKDIVGVTTSFQGEVLAAELNIPLLSLNAVSRIDLAIDGADEVDPGFQLIKGGGACHVQEKLVAARADRFVVVVDSTKLVDRLNLGFLLPVEVLPGAWRQVKQQLEALGGSAELRMAQRKAGPVVTDQGNLVLDAKLDGGISDPVALEQTINNIPGVLENGLFVNITDEVLVGEITDGVAGVRSLQKRLS
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: SODM2_ARATH
Sequence: MTTTVIIIIFVAIFATTLHDARGATMEPCLESMKTASLPDLPYAYDALEPAISEEIMRLHHQKHHQTYVTQYNKALNSLRSAMADGDHSSVVKLQSLIKFNGGGHVNHAIFWKNLAPVHEGGGKPPHDPLASAIDAHFGSLEGLIQKMNAEGAAVQGSGWVWFGLDRELKRLVVETTANQDPLVTKGSHLVPLIGIDVWEHAYYPQYKNARAEYLKNIWTVINWKYAADVFEKHTRDLDIN
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn] 2, mitochondrial, Protein MANGANESE SUPEROXIDE DISMUTASE 2, AtMSD2.
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: SFSA_GEODF
Sequence: MYLMPPLIPAVLIRRYQRFLADFQLENGEIVTAHCPNSGSMKGCAVPGSPAFISRCDKPGRKLCYTWEQVKADNCWIGINTSLPNRLVHNAIESNVIKELQGYHSIRPEVRYGINSRIDLLLSRGDELCYVEVKNVTLMEDGRALFPDAATVRGQKHLRELMEMVRLGHRAVNFFVVQRPDCSSVSPADAIDPEYGRLLRLAAANGVELLAYQAQVSRETIHLTHRLPVIL
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: TRMB_CLOPS
Sequence: MRMRRKPWARPELEACDFFVANPKENKGNWKNTFKNTENPIYLELGCGKGTFMAVHGSDHPNINYIAIDIKDEVLVLAKRNIEKAYEEKNKALDNVKLMPQEIALIDTILDSNDKIERIYINFCNPWPKDRHKKRRLTHPRQLTKYRDFLVDGGEIHFKTDDDELFEESLEYFKECNFEITYITRDLHNSGYEYNVVTEHEEMFSKQGIKIKFLIAKKL
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.