PharMolix/UniProtQA huggingface dataset:
Protein: RL1_SALEP
Sequence: MAKLTKRMRVIREKVDATKQYDINEAIALLKELATAKFNESVDVAVNLGIDARKSDQNVRGATVLPHGTGRSVRVAVFTQGPNAEAAKAAGAELVGMEDLADQIKKGEMNFDVVIASPDAMRVVGQLGQVLGPRGLMPNPKVGTVTPNVAEAVKNAKAGQVRYRNDKNGIIHTTIGKVDFDADKLKENLEALLVALKKAKPSQAKGVYIKKVSISTTMGAGVAVDQAGLSASAN
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: LEPA2_RHOBA
Sequence: MKHIRNFCIIAHIDHGKSTLADRLIQSCGGVTQREFHDQMLDSMDIERERGITIKSNTVTLNYTAKDGEAYQLNLIDTPGHVDFSHEVRRSLMACEGALMVVDASQGVEAQTVANLYLALEYDLELLPVINKIDLPAADVDRVRGEIDEDLGLDPFVAIPVSAKTGQGIEDVLEGIVKNLPAPKGDPKAPLKALVFDAFFDKYRGVILQCRVMEGTLKPKDEIHFMHADRDFTVDELGYNQFKLVPKKELTAGEVGYIVAGVKTVQDIEIGDTITLANRPADEPIPGYQPARQVVFSSVYPMSTDEYQDLTKALEKLSINDAALTFEKDSSAALGFGYRCGFLGLLHLDVVQERLQREFDIGLVISAPSVQYKIKLKDGTTQDVDNPTYWPDPSTIDSVSEPYIKAQILIPEEYVGPVMELCREHRSESQTMNYLSAGRLEVTSEMPLGEVLFDFYGKLKMITRGYGSFDYVPIEYRKTDIVKVDILVNKEPVDALAYLVHRDKSRARAMHYCEQLAEAIPRHQFKIPIQGAIGGTVIARTTIAPYRKDVTAKLYGGDVSRKKKLLEKQKKGKAKMKQFGSVNIPQKAFISVLRTDKD
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4 2, EF-4 2, Ribosomal back-translocase LepA 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MLAC1_METMF
Sequence: MSRFARLLLMVVALFFTNAWAKTVKETLRITWKEGAPNGQARELIYTNGQFPSPTLVWDEDDDVEITVYNEMAKNVTVHWHGLDQKDTPWSDGTPGLSQRPIQPGNKFVYKFKASPPGNHWYHSHEKMSLVDGLYGAIHIRPKGDRTGLWSQISQDKDDIKAMENAAHDPEYLVVSDWSQYTSEEYWKISTDSGLLVFCLDSILVNGKGEVYCPGQKFLQAELAPGLVEDAFPPGTEVSDKGCFPADLDQVQGGPWNITKRPDLIPPRVQEGCVASSHENATIVVDPSRNNGWVSMHIVAAATIAQITFSVDSHEFWLYEIDGNYVNPRKFVSAVMSAGETFSVMIKLDQKPGRYTMRIPNSGASQVLGGFAEMVYKGCESEEKTGKAYLSYGGNPTSPDVEKNSFFPWQLDTDHMSPWPPNKPRPGNADEEHLLVLGRVGAPYNYTMNTKYLYPVDFQNDDPLLFYPNATRDTENDGLVLRTKNGSWVDLILQVSTLPGDTSSFEHFMHKHGSKTWRIGFGTGVWNYTSVEEAIKERPKDFNLETPGLRDTWITAFSIGGEAYWSVFRYFVDNPGPWLFHCHIELHLMGGMGIAILDGVDAWPEHIPEEYQLC
What is the function of this protein?
Laccase; part of the Pks1 gene cluster that mediates the biosynthesis of an anthraquinone derivative pigment that contributes to conidial pigmentation that provides protection from UV radiation, heat and cold stress (PubMed:29958281).  The polyketide synthase Pks1 produces 1-acetyl-2,4,6,8-tetrahydroxy-9,10-anthraquinone though condensation of acetyl-CoA with malonyl-CoA (Probable).  The dehydratase EthD and the laccase Mlac1 further convert the anthraquinone derivative into the final conidial pigment (Probable).
What are the official names of this protein?
Laccase 1, Conidial pigment biosynthesis oxidase Mlac1.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Cell surface.
Protein: TUSB_ECO5E
Sequence: MLHTLHRSPWLTDFAALLRLLSEGDELLLLQDGVTAAVDGNRYLESLRNAPIKVYALNEDLIARGLTGQISNDIIPIDYTDFVRLTVKHSGQMAW
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
What are the official names of this protein?
Protein TusB, tRNA 2-thiouridine synthesizing protein B.
What is the protein family that this protein belongs to?
Belongs to the DsrH/TusB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: K2C80_HUMAN
Sequence: MACRSCVVGFSSLSSCEVTPVGSPRPGTSGWDSCRAPGPGFSSRSLTGCWSAGTISKVTVNPGLLVPLDVKLDPAVQQLKNQEKEEMKALNDKFASLIGKVQALEQRNQLLETRWSFLQGQDSAIFDLGHLYEEYQGRLQEELRKVSQERGQLEANLLQVLEKVEEFRIRYEDEISKRTDMEFTFVQLKKDLDAECLHRTELETKLKSLESFVELMKTIYEQELKDLAAQVKDVSVTVGMDSRCHIDLSGIVEEVKAQYDAVAARSLEEAEAYSRSQLEEQAARSAEYGSSLQSSRSEIADLNVRIQKLRSQILSVKSHCLKLEENIKTAEEQGELAFQDAKTKLAQLEAALQQAKQDMARQLRKYQELMNVKLALDIEIATYRKLVEGEEGRMDSPSATVVSAVQSRCKTAASRSGLSKAPSRKKKGSKGPVIKITEMSEKYFSQESEVSE
What are the official names of this protein?
Keratin, type II cytoskeletal 80, Cytokeratin-80, CK-80, Keratin-80, K80, Type-II keratin Kb20.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: ECFA1_CLOD6
Sequence: MDNIVKVNNISFEYITDEAKLKAIDNLSLDVKKGEFVAIIGHNGSGKSTLSKNLNAILMPTEGNILIDDMDTKEEERLWDIRQTAGMVFQNPDNQIVATIVEEDVAFGPENLGIEPKEIRRIVEESLKSVGMYDLRDRQPHLLSGGQKQRVAIAGIIAMRPKCIIFDEATAMLDPSGRKEVMKTIKRLNKEENITVIHITHFMEEAVEADRVVVMEKGKKILEGTPREVFSKIKMLKEIGLDVPCMTELSSLLIEEGINISSDILTVDEMVMELCQL
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA1, ECF transporter A component EcfA1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: IF2_RICCN
Sequence: MTDNQEIKPKKLTLGNSKLSLNKSFDSLTGAQSFVNAKSKTLVEVRKSSTGSATTLSLNKERNSLDQTVIDANKEEFNRRLSILKKAAEQSQLNDPLKISTLSKLASINQSANSKIEPLETDKEVEQKQQNTEENKVEVSAKIVQDDEDIPSQIPKKKEETFVKSPLVGKRTRYGIESEKELDKTAESKIIAPKIKLEEPKKFKKADLFNMLSDDESGSGRTRSLAAIKRAREKEKRKLVSQAPEKVYREVTIPEAIGVGDLANAMSERVADVIKELMKLGILANASQTIDADTAELVATNLGHTVKRVQESDVENVLISDDKVEDLRTRAPVVTVMGHVDHGKTSLLDSLKSTDIAAGELGGITQHIGAYRVTLADGRAITFIDTPGHEAFSEMRSRGAKVTDIVIIVVAADDGIKTQTVEAINHAKAAGVPIIVAINKIDKPDIDIERVKNELYVHEIIGEEAGGDIMIIPISALKKINLDKLEEAILLIAEMQDLKANPFGSAAGVVIESKIEQGRGTLTTILVQRGTLRNSDIIIAGTAYGKVKKMTNDKGLEIVEATPSVPVEIQGLNEVPFAGDKFNVVQNEKQAKDIAEYRMRLAKEKKISIAPRSSLEDLFLKASGNSKIKELPLIIKGDVQGSVEAISGSLLKLPSDEIKLRILHSGVGPITESDVSLAHASSAIIVGFNVRAGANALTAAEKEKVDIRYYSIIYHLIDDIKAIMSGMLDPIVREQYIGSAEMRQIFNITKVGKIAGSYVTKGIIKKGAGVRLLRDNVVIHEGKLKTLKRFKDEVKEVREGYECGIAFENYQDIREGDTVEVFELIQEQRQL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL33_WOLPM
Sequence: MAKKNASLLVKLVSTAIKITKTGEEKSTGYFYVKKRNPKKLTKKLEFRKYDPVVRRHVLFKEEKLK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: YO160_YEAST
Sequence: MENIAFICLQSCTRGIYGCQFYSATLENYHNISFPIFLLQTTLFNHCISLNWSKAVFNRIKRRKYMMELKKHCYNYQVSRIGNRKKNGCFFLKMANNRVFSVKNSPRLLLFFI
What are the official names of this protein?
Uncharacterized protein YOL160W.
Protein: TRIM9_HUMAN
Sequence: MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDYDYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPATHLSPALAPVPRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDFDLSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVPADGYILELDDGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSEVAWFAFDPGSAHSDIILSNDNLTVTCSSYDDRVVLGKTGFSKGIHYWELTVDRYDNHPDPAFGVARMDVMKDVMLGKDDKAWAMYVDNNRSWFMHNNSHTNRTEGGITKGATIGVLLDLNRKNLTFFINDEQQGPIAFDNVEGLFFPAVSLNRNVQVTLHTGLPVPDFYSSRASIA
What is the function of this protein?
E3 ubiquitin-protein ligase which ubiquitinates itself in cooperation with an E2 enzyme UBE2D2/UBC4 and serves as a targeting signal for proteasomal degradation.  May play a role in regulation of neuronal functions and may also participate in the formation or breakdown of abnormal inclusions in neurodegenerative disorders.  May act as a regulator of synaptic vesicle exocytosis by controlling the availability of SNAP25 for the SNARE complex formation.
What are the official names of this protein?
E3 ubiquitin-protein ligase TRIM9, RING finger protein 91, RING-type E3 ubiquitin transferase TRIM9, Tripartite motif-containing protein 9.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, dendrite. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Synapse. Cytoplasm, cytoskeleton. Note=Enriched at synaptic terminals where it exists in a soluble form and a synaptic vesicle-associated form. Associated with the cytoskeleton (By similarity). Found in proximal dendrites of pyramidal neurons in the cerebral cortex and hippocampus, and Purkinje cells in the cerebellum (PubMed:20085810).
Protein: NADE_SHEB2
Sequence: MKAQILREMKVLTAIEPEFEVQRRVAFIKTKLKEARSKALVLGISGGVDSSTAGRLCQLAVDSLNHENSQGGYQFIAVRLPYQIQKDEHEAQLACQFIQPSKLVTVNVHQGVDGVHSATVAALAEAGLPLPDVAKVDFVKGNVKARMRMIAQYELAGLVGGLVVGTDHSAENITGFYTKWGDGACDLAPLFGLNKRQVRQLAAYLGAPESLVHKAPTADLEDNKPLLEDEVALGLTYAQIDDFLEGKDVGKAVEDKLIGIYKATQHKRQPIPTIYD
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: RS18_RICAH
Sequence: MLKSNNASETVTHKVGDKTAKKVFFRRRKGCPLSVHNAPVIDYKNPELLIKFVSEGGRMLPSRITNVCAKKQRKLNNAIKIARILALLPFVFQAK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: GLYA_YERPN
Sequence: MLKREMNIADYDADLWRAMEQEVVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGGCEYVDVVEQLAIDRAKALFGADYANVQPHSGSQANVAVYSALLKPGDTVLGMNLAHGGHLTHGSPVNFSGKLYNIVPYGIDESGQIDYEDLARQAEIHKPKMIIGGFSAYSGIVDWAKMREIADSIDAWFFVDMAHVAGLVAAGVYPNPVPHAHIVTTTTHKTLAGPRGGLILAKGGDEDLYKKLNSSVFPGNQGGPLMHVIAGKAVALKEAMEPEFKIYQQQVAKNAKAMVAVFLERGYKVVSGGTDNHLFLLDLVDKDITGKDADAALGRANITVNKNSVPNDPKSPFVTSGVRIGSPAITRRGFKEAESRELAGWMCDVLDNINDEATIERVKQKVLAICARLPVYA
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_XYLFM
Sequence: MPTEANTYDPQRIESIAQHYWDSTHAFEVNEHSNKPKYYCLSMLPYPSGALHMGHVRNYTIGDVISRYKRMTGHNVLQPMGWDAFGLPAENAAIKNKVAPAQWTYKNIERMRTQLKSLGYAINWSREFATCQPDYYVHEQHMFTRLMRKGLAYRRNALVNWDPVDQTVLANEQVIDGRGWRSGAPVEKREIPQWFLRITDYAQELLDGLNTLDDWPEPVKTMQRNWIGRSEGLEIRFEVRDVDNNALEALRVFTTRPDTLFGVTFVSIAPEHPLALHAAKSNPGLAGLLTQMKQGGLSEAELKTQEKRGMDTGLKAIHPITNEQLPVWVANFVLMAYGTGAVMAVPGHDQRDQEFANKYGLPIRQVIALKEPKNQDESTWEPDVWRDWYADKTREFELINSAEFDGLDYQGAFEVLVERFERQGRGQRRVNYRLRDWGVSRQRYWGCPIPVIYCPTCGAVPVPENQLPVILPENVAFSGTGSPIKTDSEWRKTTCPECGGPAERETDTFDTFMESSWYYARYTSPNAREMLDKRANYWLPVDQYIGGIEHAILHLMYFRFYHKLMRDARLVDSDEPAINLLTQGMVIAETFYRKNPDGSKDWINPADVNVECDERGRITGATLISDGQPVLIGATEKMSKSKNNGVDPQIMVTKYGADTVRLFSMFAAPPEQSLEWNEAGVEGMARFLRRLWTQVHHHASHGPATALDITALDTAQKAIRCKTHNTIARVEDDYGRRRSFNTAIAAVMELSNTLARFDDTTTQSHAVRQEALETMVLLLNPITPHTSHALWQTLGHPETLLEDLPFPKVDTTALVRETATLAVQVNGKLRGTIEVATDAPREHIENNALTEPNTARFLEGLTVLKIIIVPGKIVNIVAR
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_BURPS
Sequence: MQQRRRPPIASRETLQALLSEGAQALGVALSDAQRGALLDYVALLAKWNAVYNLTAIRDPRQMLIQHILDSLSIVPHLGAHGAAAAALDVGSGGGLPGVVLAIALPGWRVTLNDIVHKKSAFQNQAKAELKLGNLSVVTGRVETLRPGADVPAKFDVIVSRAFADLADFVTLARHLVAPGGSIWAMKGVRPDEEIGRLPDGARVKQMIRLTVPSLDAERHLIEVELDEAI
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_STAAE
Sequence: MEHTIAVIPGSFDPITYGHLDIIERSTDRFDEIHVCVLKNSKKEGTFSLEERMDLIEQSVKHLPNVKVHQFSGLLVDYCEQVGAKTIIRGLRAVSDFEYELRLTSMNKKLNNEIETLYMMSSTNYSFISSSIVKEVAAYRADISEFVPPYVEKALKKKFK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_ECO45
Sequence: MLKREMNIADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGGCEYVDIVEQLAIDRAKELFGADYANVQPHSGSQANFAVYTALLEPGDTVLGMNLAHGGHLTHGSPVNFSGKLYNIVPYGIDATGHIDYADLEKQAKEHKPKMIIGGFSAYSGVVDWAKMREIADSIGAYLFVDMAHVAGLVAAGVYPNPVPHAHVVTTTTHKTLAGPRGGLILAKGGSEELYKKLNSAVFPGGQGGPLMHVIAGKAVALKEAMEPEFKTYQQQVAKNAKAMVEVFLERGYKVVSGGTDNHLFLVDLVDKNLTGKEADAALGRANITVNKNSVPNDPKSPFVTSGIRVGTPAITRRGFKEAEAKELAGWMCDVLDSINDEAVIERIKGKVLDICARYPVYA
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCCT_ECOSM
Sequence: MKTGIVTTLIALCLPVSVFATTLRLSTDVDLLVLDGKKVSSSLLRGADSIELDNGPHQLVFRVEKTIHLSNSEERLYISPPLVVSFNTQLINQVNFRLPRLENEREANHFDAAPRLELLDGDATPIPVKLDILAITSTAKTIDYEVEVERYNKSAKRASLPQFATMMADDSTLLSGVSELDAIPPQSQVLTEQRLKYWFKLADPQTRNTFLQWAEKQPSS
What are the official names of this protein?
UPF0319 protein YccT.
What is the protein family that this protein belongs to?
Belongs to the UPF0319 family.
Protein: VSGP_EBOEC
Sequence: MGVTGILQLPRDRFKRTSFFLWVIILFQRTFSIPLGVIHNSTLQVNDVDKLVCRDKLSSTNQLRSVGLNLEGNGVATDVPSATKRWGFRSGVPPKVVNYEAGEWAENCYNLEIKKPDGSECLPAAPDGIRGFPRCRYVHKVSGTGPCAGDFAFHKEGAFFLYDRLASTVIYRGTTFAEGVVAFLILPQAKKDFFSSHPLREPVNATEDPSSGYYSTTIRYQATGFGTNETEYLFEVDNLTYVQLESRFTPQFLLQLNETIYTSGKRSNTTGKLIWKVNPEIDTTIGEWAFWETKKTSLEKFAVKSCLSQLYQTEPKTSVVRVRRELLPTQGPTQQLKTTKSWLQKIPLQWFKCTVKEGKLQCRI
What is the function of this protein?
Viroporin that permeabilizes mammalian cell plasma membranes.  It acts by altering permeation of ionic compounds and small molecules.  This activity may lead to viral enterotoxic activity.
What are the official names of this protein?
Pre-small/secreted glycoprotein, pre-sGP.
What is the protein family that this protein belongs to?
Belongs to the filoviruses glycoprotein family.
What are the subcellular locations of this protein?
[Small/secreted glycoprotein]: Secreted. SUBCELLULAR LOCATION: [Delta-peptide]: Secreted.
Protein: SBHS7_THYVU
Sequence: MSTISINHVGILRNPLQCKNKRTSINKPWSLSLPRSSPASRLVKPCRVSSKVDTMPDEITRRSGNYEPSLWDLDFIQSLDNHHPYVKEMQLKREEELIVQVKMLLGTKMEAVKQLELIDDLKNLGLSYFFRDEIKTILTSIYNNSFENNNQVGDLYFTALGFRLLRQHGFNVSQQIFDCFKDNDFDETLIGEDTKGILQLYEASFHLREGENTLELARQISTKYLQKKVDEGSINDENLSSWIRHSLDLPLHWRIQRLEARCFLDAYAAREDKNPLIFKLAELDFNIIQATQQQELKEISRWWNDSSLAEKLPFVRDRVVECYFWAVGLFEGHEFGFQRKITAAIIILITAIDDVYDVYGTLDELQLFTDVIRRWDTQSIDQLPYYMQLCYLALYNFVSDLAYDILKDRGLNTIPYLHRSWVELVEAYLKEAGWYENGYTPSLEEYLTNATISIGVPPIVLPVEVSLPNSTIHRTQFDRPHKILDLSARVLRLADDLGTASSELERGDVPKAIQCYMKDNNASEEEAREHVRFMIREAWKELNTAMAEPDNCPFTEQTVEAAANLGRAAQFIYLEGDGHAHFQIHQHLENLFFHPCV
What is the function of this protein?
Involved in the biosynthesis of phenolic monoterpenes natural products (PubMed:23246843).  Monoterpene synthase which catalyzes the conversion of geranyl diphosphate (GPP) to sabinene hydrate, specifically (E)-sabinene hydrate, and the formation of minor amounts and traces of several other monoterpenes (e. g.  mainly alpha-pinene, limonene and alpha-terpineol) (PubMed:23246843).
What are the official names of this protein?
(E)-sabinene hydrate synthase, chloroplastic, Terpene synthase 7, TvTPS7.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PPID_EMENI
Sequence: MAESKRPRVFFDIQIGQQQTGRIAFELFNDVVPKTAENFRALCTGEKGMGKQGKPLHFKGSIFHRVIKQFMIQGGDFTAFNGTGGESIYGEKFPDENFELKHDRPFLLSMANSGPGTNGSQFFITTVPTPHLDGKHVVFGEVINGKSVVRKIENMPTQADKPTTDVTIAECGELTGEDYDNADKQTPDATGDPYEDFPDDHQGEELSAPVCFKIASELKNFGNTAFKNGNIALGLEKYQKGLRYLNEFPEPEENDPKDLEPQMKSLRFTLHSNSSLLANKLGQFKNGKTWATYALDVADAASAKDADRAKVYYRRAVAESGLKEEDEALKDLEQASTLAPSDAAIAAETARVKKAIKAREAQEKATARKFFS
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase D, PPIase D, Rotamase D.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase D subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPP_LEPBA
Sequence: MDNTLNAFLRGIIEAATEFLPVSSTGHLFLFSYFFPFQNLSVPHEAFEDLFDIFIQTGAILSVVVLYYKTLWSHLVEAVRFGLGKSTDRSGFQFYLNLIVGILPILILGFLLKSQLDQIKMRSDLLLILGMSWFVGGIIMVFVEKRHLDESSGKTIGFKESIIVGFLQCFALIPGVSRSAATIISARTMGVSKKDSAEFSFFLAIPVLTLAGIYKLYKHRQILNSETIGLLLFGSIISFIICYFIIRLFMAFIRRRSFISFGVYRILLGLLVILYFVRY
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HSLO_BACC0
Sequence: MKDYLVKALAFDGEVRAYSVRTTNTVSEAQRRHDTWRTASAALGRSLTAGTMMGAMLKGDQKLTIKVEGNGPIGPILVDAHANGDVRGYVTNPHVDFEGTEQGKLRVYQAVGTEGFVTVIKDIGMREPFIGQSPIVSGELGEDFTYYFAVSEQTPSSVGVGVLVNGDDSILAAGGFILQIMPGAQEETISFIEERLQKIPPVSTLIEQGLSPEELLYAVLGEDKVKVLETMDVQFNCTCSRERIESVLISLGKTELEQVREEEEETEVHCHFCNERYKFSKEDITNLIENL
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLA3_YEAST
Sequence: MSDSIISFAAFILADAGLEITSDNLLTITKAAGANVDNVWADVYAKALEGKDLKEILSGFHNAGPVAGAGAASGAAAAGGDAAAEEEKEEEAAEESDDDMGFGLFD
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S acidic ribosomal protein P1-beta, Ax, L12eIIB, L44', Large ribosomal subunit protein P1-B, P1B, YP1beta.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein P1/P2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DFP_MANSE
Sequence: MWFTYTFAMLLVAGYVSAYGSGAPQSACQDMIPRHPVGPQNTSAPYIITTSTKVVKAGTPMQVTISGKKPENTMRGILLQARQGDKIVGKFTLDDNDSFAQLLDCGEPGNAITHKRHPPEFDKQTVTFTWTPPADLNDNIRFRATIAYSGAVFWLGVESPVVKVVA
What is the function of this protein?
May have antimicrobial activity.
What are the official names of this protein?
Putative defense protein Hdd11-like.
What is the protein family that this protein belongs to?
Belongs to the insect defense protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: GRPE2_PONAB
Sequence: MAVRSLWACRLRVQRLLAWSAAWESKGWPLPFSTATQRTAGEDCRSEDPPDELGPPLAERALRVKAVKLEKEVQDLTVRYQRAVADCENIRRRTQRCVEDAKIFGIQSFCKDLVEVADILEKTTECISEESEPEDQKLTLEKVFRGLLLLEAKLKSVFAKHGLEKLTPIGDKYDPHEHELICHVPAGVGVQPGTVALVRQDGYKLHGRTIRLARVEVAVESQRRL
What is the function of this protein?
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.  Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins.  Stimulates ATPase activity of mt-HSP70.  May also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70 (By similarity).
What are the official names of this protein?
GrpE protein homolog 2, mitochondrial, Mt-GrpE#2.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: CRBL_VESCR
Sequence: FLPLILRKIVTAL
What is the function of this protein?
Mast cell degranulating peptide.  Induces the chemotaxis of neutrophils.  Has antimicrobial and hemolytic activity.
What are the official names of this protein?
Crabrolin.
What is the protein family that this protein belongs to?
Belongs to the MCD family. Crabrolin subfamily.
What are the subcellular locations of this protein?
Secreted.