PharMolix/UniProtQA huggingface dataset:
Protein: APOC1_RABIT
Sequence: APDFSTLELIPDKLKEFGNTLEEKARMA
What is the function of this protein?
Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor.  Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL.  Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP).  Binds free fatty acids and reduces their intracellular esterification (By similarity).  Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein.
What are the official names of this protein?
Apolipoprotein C-I, Apo-CI, ApoC-I, Apolipoprotein C1.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein C1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: MURI_SYNSC
Sequence: MTPQLLGFFDSGLGGLTVLRRVLERHGSVPCVYLGDTARVPYGNRQPDDIRRIAAEVVGWLRDQKVSTVVMACNTTNALARDVADGQAGAPVIGLIGAAAAMVETRRVGVLATPATVASSAYRASIEALHPGSMVIEQACPAFVPLIESGDMNSDDLRRAAQAYLEPLLAASVESIVLGCTHYPLLVPLLRQLLPESVQIIDPAIGVARQLDAVLRSPGPISAVPRPFSLESCRFCVTADPDGFAMRATPWLGQRPDVSLQLLPD
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: CSRA_BORDL
Sequence: MLVLSRKANESIKIDSNIEISILEIKKDSVKIAIKAPENIKILRSEIYDIIKEENKKSILQDKNNIHKIKKLFDYFSK
What is the function of this protein?
A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation.  Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
What are the official names of this protein?
Translational regulator CsrA.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRD_PSEA7
Sequence: MYTLARQLLFKLSPETSHELSIDLIGAGGRLGLNRLLAPRPASLPVSVLGLEFPNPVGLAAGLDKNGDAIDGFGQLGFGFIEIGTVTPRPQPGNPKPRLFRLPQASAIINRMGFNNHGVDHLLARVRAAKYRGVLGINIGKNFDTPVERAVDDYLTCLDKVYADASYVTVNVSSPNTPGLRSLQFGDSLKQLLEALRQRQEDLALRHGRRVPLAIKIAPDMSDEETALVAAALVEAGMDAVIATNTTLGREGVEGLPHGDEAGGLSGAPVREKSTHTVKVLAGELGGRLPIIAAGGITEGAHAAEKIAAGASLVQIYSGFIYKGPALIREAVDAIAALPRRN
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CCME_SHEPW
Sequence: MNPRRKKRLTLAVALIGGVAAIASLLLYALNSNLNLFFTPTEIVQGKKDTGVMPEIGQRIRVGGMVTIGSMVRDPDSLHVEFAVHDAAGGEIIVTYDDLLPDLFREGQGIVAQGVLSAPGKLEATEVLAKHDENYMPPEVAEAMGQSHEKLDYSEDQSKAGGYK
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: RL15_STRZP
Sequence: MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGGGVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIVKAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: COAA_LEIXX
Sequence: MAENGAARGGTSAGGDSSTPFVELGRADWAELAQSARLPLQEAEIVQLRGLGDPLDMREVGEVYLPLSRLLNLYVGGTRQLHRVTSDFLGERAQATPFVIGVAGSVAVGKSTIARLLRELLSRWDDTPRVELVTTDGFLLPNAELERRGLMRRKGFPESYDRRALLRFVTAVKSGAREVRAPFYSHLSYDIVPGAEIVVRQPDVLIVEGLTVLQPAGGGTRLAVSDLFDFSVYVDARTRDIAHWYQERFLTLQRGAFANPKSYFHRYASLTEEEARARAAAIWADINEPNLTQNIRPTRSRAKLVLRKDADHTVSSVLLRKI
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_LEGPH
Sequence: MKRIKSGDEVIVIAGKSKGHIGKVLRVIDDAVVVEGGNLIKKHIKPNPQKPENKGGIIAREAPLHVSNVAHYNPVTKKADKVGFKYLESNGVSKKVRYYKSNNEIIDRI
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: ETFB_ORYSI
Sequence: MKILVAVKRVVDYAVKVRVRPDRTGVETASVKMSMNPFCEIAVEEALRLREAGAATEVVAATVGPSQSADTLRTALAMGADRAVHVLHDPDPSRPLLPLAVAKILRALALQENPGLVILGKQAIDDDCNQTGQMLAGLLNWPQGTFASKVILNKEKATVEREVDGGIETISLDLPAVITTDLRLNQPRYATLPNIMKAKSKVIKKVTPEDLDVDIRSDMEVVEVTEPPKRKAGVILSSVDELIDRLKNEARVL
What is the function of this protein?
The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase.  It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity).
What are the official names of this protein?
Electron transfer flavoprotein subunit beta, mitochondrial, Beta-ETF.
What is the protein family that this protein belongs to?
Belongs to the ETF beta-subunit/FixA family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: PDXH_LEPIC
Sequence: MDPKISEIRKSYTLSSLEIEDAGSDPVLFFQKWFEEAVQSEVLEVNAMTLATVTQDGKPDARIVLLKGILKESFLFYTNYESRKGTELETNPNVCLVFFWPELERQVRIEGNVTKVSREVSKEYFHSRPRESQIGALASPQSQKIPDRKFLEGRFQKFTNQYQNKEVDLPNHWGGYAVYPCRIEFWQGRSSRLHDRIVFERDTSSSWEKFRIAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: ATPL_MYCCT
Sequence: MLHTAFISNILANYLGAMSVILPNILTVTGDIKYIGAGLASVGILGTGVGQGLIGQGACLAIGRNPEMASKVTSTMIVSAGISESGAIYSLVIAILLIFVV
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL2_VARPS
Sequence: MAVIKMKPTSPGQRGAVKISRDHLFKGAPHAPLLEPQFQKAGRNNNGHITIRHRGGGAKHHYRVVDFVRNKDGIPAKVERIEYDPNRTAHIALVCYADGERRYIIAPRGLEAGATLLSGSEAPIRAGNTLPIRNIPVGSTIHCIELQPGKGAQIARSAGTSATLLAREGVYAQVRMRSGEVRRIHIECRATIGEVANEEHSLRQLGKAGVKRHMGIRPTVRGVVMNPVDHPHGGGEGKTGEGRHPVDPWGNLTKGYRTRNNKRTQVFIVSRRKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: TAL_CLOB6
Sequence: MKIFIDTANVEEIRKASELGVLSGVTTNPSLIAKEGRDLKEVVEEICSIVDGPISAEVISLEYEKMIEEGRELSKLHKNIVIKIPMCEEGLKAVSVLSKEGIKTNVTLIFSSMQALLAARAGATYVSPFLGRLDDIGNPGIEVVKQIADMFKIHEIKTEIIAASVRTPMHVLEAAMAGSHIATIPYKVIIQMSKHALTDIGIEKFMKDYEKAFGESK
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMTC1_MOUSE
Sequence: MLVTRGDRGGGERAPSRRPRCGLVPAGAAALLAGASCLCYGRSLRGEFVHDDVWAIVNNPDVRPGTPLRWAIFANDFWGKGLADSTSHKSYRPLCVLSFRLNIFLTGMNPFYFHAVNVILHCLVTLVLMYTCDKTVFKNRGLAFVTALLFAVHPVHTEAVAGIVGRADVLACLLFLLAFLSYQRSLDQGCAGQCFPTTASPFFLLLSLFLGTCAMLVKETGITVFGVCLVYDLFSPSHKQDKLSNGAVCQHSSGQPGSPQPSSQQAHPHRESRKQRFPHKDSWGGCHSPLPPEPKSSGFPMSPRAMWSLMRCLTGSTNRNFLLTLRPFLKRAILVISYVTVILYFRLWIMGGTMPLFSEQDNPASFSPYILTRFLTYSYLLAFNVWLLLAPITLCYDWQVGSIPLVETIWDVRNLATILLAVVMALLSLHCVAAFKRLEHKEVLAGLLFLVFPFIPASNLFFRVGFVVAERVLYMPSMGYCILFVHGLSKLCAGLSRCGATSLMASTVLLLLLFSWKTVKQNEIWLSRESLFRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTLTKDMAEAKMYYQKALQLHPQHNRALFNLGNLLKSQEKTEEAIMLLKESIKYGPDFADAYSSLASLLAEQERFKEAEDIYQAGIKNCPDSSDLHNNYAVFLVDSGFPEKAVAHYQQAIQLSPSHHVAVVNLGRLYRSLGENSKAEEWYRRALKVARTAEVLSPLGALYYNTGRHKEALEVYREAVSLQPSQRELRLALAQVLAVMGQTKEAEKITSHIVSEEPRCLECYRLLSAIHSKQEHHGKALEAIEKALQLKPKDPKVISELFFTKGNQLREQNLLDKAFESYEAAVTLDPDQAQAWMNMGGIRHIQGSYVSARAYYERALKLVPDSKLLKENLAKLDRLERRLQEVRERDQT
What is the function of this protein?
Transfers mannosyl residues to the hydroxyl group of serine or threonine residues.  The 4 members of the TMTC family are O-mannosyl-transferases dedicated primarily to the cadherin superfamily, each member seems to have a distinct role in decorating the cadherin domains with O-linked mannose glycans at specific regions.  Also acts as O-mannosyl-transferase on other proteins such as PDIA3.
What are the official names of this protein?
Protein O-mannosyl-transferase TMTC1, Transmembrane and TPR repeat-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the TMTC family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Endoplasmic reticulum.
Protein: 6PGL_CHLTR
Sequence: MATLISLNDANRMLIADSQEEFLQIACYDWISTANKAIHKRGAFYVALSGGKTPLQIFQEIVKKRAAISDCSKIVVFWGDERANEDVEAGSNYLKAMDILKGLRIPEDQIFRMDTADPKGDEAYEALIQKYVPDAIFDMVMLGVGEDGHTLSLFPETHALEEKERFVVFNEVPQLHTRRMTLTFPIVRQARHLVAYVQGENKQDLFHKLVHPLGRDTFPIERVGTPLNPVQWVLSSDSCRKTDLADIPADCKLEMF
What is the function of this protein?
Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
What are the official names of this protein?
6-phosphogluconolactonase, 6PGL.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
Protein: YIHO_SALTY
Sequence: MSNHDPLTLKLSLREKCAYGVGDFGSNLMLCIGTLYLLKFYTDELGMPAYYGGIIFLVAKFFTAFTDMLTGVLLDSRRNIGAKGKFRPFILYASFPVALVATAQFFATHFTLPVKTAFATVLFMLFGLFYSLMNCSYGAMVPAITKNPHERAQLAAWRQGGATIGLLLCTVGFMPIQALFTRSPSLGYLIAAVIFSVCGLFSMWWCFSGVKERYIETVPDTHKPSILKSFCAIFRNPPLLVLCVANLCTLAAFNIKLAIQVYYTQYVLNDIHLLSWMGFFSMGCILIGVLLVPAAVKRFGKKQVYLGGLILWAVGDILNFIWGGTSFLFVIFSCIAFFGTAFVNSLNWALVPDTVDYGEWKTGIRAEGSVYTGYTFSRKISAALAGFLPGIMLTQIGYIPNIAQSDTTLLGLRQLIFLWPCGLAIIAALTMGFFYKLNEQRFAFIIEEIAQRKKTGNQIVATNNKQSISTVNN
What is the function of this protein?
Could be involved in sulfoquinovose import.
What are the official names of this protein?
Putative sulfoquinovose importer.
What is the protein family that this protein belongs to?
Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MED18_DICDI
Sequence: MFQQNKHHQQQQQQQQQQGVVQSGVASATVNNPSESIVAGNIYECSLHGILSTPSSTFIQRAKGMMRCEHPVSYKEMVFKSTVQSAGPSWAEGSILPSEIHVRYEKNTVYVRYVGVPQIKDNINAMIRNVVDIKSSETFFIYLENLGYVKDYEYFVDGYQYSTYNLSLFLVNHRRVLNDGTKGELLNKHSMVELQCLSGEEGFVAAAEYLNTYAEYLYPFVELIKFDHRLLTAENSNTPTTNVNVVGGYNR
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Putative mediator of RNA polymerase II transcription subunit 18, Putative mediator complex subunit 18.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 18 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPL_STAA9
Sequence: MNLIAAAIAIGLSALGAGIGNGLIVSRTVEGVARQPEARGQLMGIMFIGVGLVEALPIIGVVIAFMTFAG
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NUOH_CHLTE
Sequence: MSSSPSLNTWSDALSGFSIGWFPLGLVIVAAIPLVFIALYALTYGVYGERKISAFMQDRLGPMEVGFWGLLQTLADILKLLQKEDIVPTVADKFLFVIGPGILFVGSFLAFAVLPFGPAFIGADLNVGLFYAVGIVAIEVVGILAAGWGSNNKWALYGAVRSVAQIVSYEIPASIALLCAAMLAGTLSMQQIILMQAGPNGFLHWFLFTNPIAWLPFLIYFISSLAETNRAPFDIPEAESELVAGYFTEYSGMKFAVIFLAEYGSMFMVSAIISIAFLGGWTSPLPNIGGLELNTMTSGPVWGAFWIIMKGFFFIFVQMWLRWTLPRLRVDQLMYLCWKVLTPFSLVSFVLTAIWVINH
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RR11_CHLVU
Sequence: MAKKIEKSAKKKFREKVLLGVAHIQSTFNNTIVTITTNKGNVLAWSSAGACGFKGARKKTPLAAKQAAENAAQTCVSQGMREIRVNVKGAGAGREAALRGLRDAGLNITIIRDITPIPHNGCRPPKKRRI
What are the official names of this protein?
30S ribosomal protein S11, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: AL14E_RAT
Sequence: MDPCSVGVQLRTTHDCHKTFYTRHTGFKTLKELSSNDMLLLQLRTGMTLSGNNTICLHHVKIYIERFEELQKSCCDPFNIHKKLAKKNLHVIDLDDATFLSAKFGRQLVPGWKLCPKCTQIINGSVDVDSDDRQRRKPESDGRTAKALRSLQFTNPGKQTEFAPESGKREKRKLTKNASASSDRQIIPAKSKVYDSQGLLIFSGMDLCDCLDEDCLGCFYACPTCGSTKCGAECRCDRKWLYEQIEIEGGEIIHNKHAGKAYGLLSPCHPYDILQK
What is the function of this protein?
Through its interaction with ARL14 and MYO1E, may connect MHC class II-containing cytoplasmic vesicles to the actin network and hence controls the movement of these vesicles along the actin cytoskeleton in dendritic cells.
What are the official names of this protein?
ARL14 effector protein, ARF7 effector protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYQ_ECO8A
Sequence: MSEAEARPTNFIRQIIDEDLASGKHTTVHTRFPPEPNGYLHIGHAKSICLNFGIAQDYKGQCNLRFDDTNPVKEDIEYVESIKNDVEWLGFHWSGNVRYSSDYFDQLHAYAIELINKGLAYVDELTPEQIREYRGTLTQPGKNSPYRDRSVEENLALFEKMRAGGFEEGKACLRAKIDMASPFIVMRDPVLYRIKFAEHHQTGNKWCIYPMYDFTHCISDALEGITHSLCTLEFQDNRRLYDWVLDNITIPVHPRQYEFSRLNLEYTVMSKRKLNLLVTDKHVEGWDDPRMPTISGLRRRGYTAASIREFCKRIGVTKQDNTIEMASLESCIREDLNENAPRAMAVIDPVKLVIENYQGEGEMVTMPNHPNKPEMGSRQVPFSGEIWIDRADFREEANKQYKRLVLGKEVRLRNAYVIKAERVEKDAEGNITTIFCTYDADTLSKDPADGRKVKGVIHWVSAAHALPVEIRLYDRLFSVPNPGAADDFLSVINPESLVIKQGFAEPSLKDAVAGKAFQFEREGYFCLDSRHSTAEKPVFNRTVGLRDTWAKVGE
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YNFA_SALPK
Sequence: MLKTTLLFFVTALCEIIGCFLPWLWIKRGASVWWLLPAAASLALFVWLLTLHPAASGRVYAAYGGVYVCTALLWLRVVDGVRLTVYDWCGALIALCGMLIIVVGWGRT
What are the official names of this protein?
UPF0060 membrane protein YnfA.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MTAP_PROMA
Sequence: MINKHFSSEEIEQDGKSCLLKNARLGVLGGSGLYSIDSIENIKELDIETPYGKPSDSLRIGNLGGMEVVFLARHGRHHIYTPTEIPYRANIWALRSLNVRWILSPSAVGSLQEQVRPLDMVVPDQFIDRTHQRPLTFFCDGAVAHVTMADPFCPTLSRLLAEEGELLMPEARQVHKGGTYLAMEGPAFSTRAESQLYRSWGCKVIGMTNHTEARLAREAEIAYTSLSMVTDYDCWHEGFGNVSVDLVIENLAANAKLASKIVEATAKRISKLLPPSEAHTALKNSLMTSKDKVSETTREKINLFTENYWGKFNK
What is the function of this protein?
Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate.  Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis.  Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine.  Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
What are the official names of this protein?
S-methyl-5'-thioadenosine phosphorylase, 5'-methylthioadenosine phosphorylase, MTA phosphorylase, MTAP.
What is the protein family that this protein belongs to?
Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
Protein: KCNJ5_HUMAN
Sequence: MAGDSRNAMNQDMEIGVTPWDPKKIPKQARDYVPIATDRTRLLAEGKKPRQRYMEKSGKCNVHHGNVQETYRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFGFIWWLIAYIRGDLDHVGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEGIILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDLRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQKSPFWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEKGFYEVDYNTFHDTYETNTPSCCAKELAEMKREGRLLQYLPSPPLLGGCAEAGLDAEAEQNEEDEPKGLGGSREARGSV
What is the function of this protein?
This potassium channel is controlled by G proteins.  Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it.  Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages.  The inward rectification is mainly due to the blockage of outward current by internal magnesium.  Can be blocked by external barium.
What are the official names of this protein?
G protein-activated inward rectifier potassium channel 4, GIRK-4, Cardiac inward rectifier, CIR, Heart KATP channel, Inward rectifier K(+) channel Kir3.4, IRK-4, KATP-1, Potassium channel, inwardly rectifying subfamily J member 5.
What is the protein family that this protein belongs to?
Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ5 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y1718_ARCFU
Sequence: MVVMVKIVHAQTVLPENVLEELKRKTGENATKDAIAKAVEHYLMCPYTHEAPLEKRLEEVIKKKKK
What are the official names of this protein?
Uncharacterized protein AF_1718.
Protein: DIVIB_LACLA
Sequence: MSEKDNNLTPWQQKHLEYQKRKAEEAKKEKKANQPKKVHFSSPFLKSLPKTEKNFDDTRDEAESAELLEEGFETNNEETQSSEAPIENEKIIAQLEQLSQENEYEYEEEQIKRPSRFFSLFKGSAPLLKKMWPALAIVVLVFVGSLYLISPLSKISTFSVSGNANESSEQVALASGIQTSDSIFNILNNKEKIEATIEQKFPRISAVTINYHFPNRFEAIVKEHTNSVYVKRNDQTYLVLNNGYVITTPVDATKLEKLPVLQNFNDEEVKTFVNAYETLKPAIKSLMTNVTKTPTDATKDFIAIDMSDGNQVRVSLSQLADRLPYYPSVAKQVQAPQVVDMEAGIYTKPKAAYDAYLSQLSTSKSASISAQNAKKTDASSENTAQSTTTSSN
What is the function of this protein?
Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.
What are the official names of this protein?
Cell division protein DivIB.
What is the protein family that this protein belongs to?
Belongs to the FtsQ/DivIB family. DivIB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: AROQ_FRATT
Sequence: MDVLVINGPNLNLLGTRQPQFYGHKTLADINNDLLKIAKENNINIDFYQSNHEGQIIDKIQQTAAKIIIINPAAFTHTSVAIRDAFLAINKPFIEIHLSNIYNREEFRTKSFLSDIAYGCIFGFGPNGYTLALIEAINYINMKGE
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: FLAA_RHIML
Sequence: MTSILTNNSAMAALSTLRSISSSMEDTQSRISSGLRVGSASDNAAYWSIATTMRSDNQALSAVQDALGLGAAKVDTAYSGMESAIEVVKEIKAKLVAATEDGVDKAKIQEEITQLKDQLTSIADAASFSGENWLQADLSGGAVTKSVVGSFVRDGSGSVAVKKVDYSLNANSVLFDTVGDTGILDKVYNVSQASVTLTVNTNGVESQHTVAAYSLESLTEAGAEFQGNYALQGGNSYVKVENVWVRAETAATGATGQEIAATTTAAGTITADSWVVDVGNAPAANVSAGQSVANINIVGMGAAALDALISGVDAALTDMTSAAASLGSISSRIDLQSEFVNKLSDSIESGVGRLVDADMNEESTRLKALQTQQQLAIQALSIANSDSQNVLSLFR
What is the function of this protein?
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.  Homomer of FlaA is able to form a functional filament.
What are the official names of this protein?
Flagellin A.
What is the protein family that this protein belongs to?
Belongs to the bacterial flagellin family.
What are the subcellular locations of this protein?
Secreted. Bacterial flagellum.
Protein: RECR_MANSM
Sequence: MQTSPLLENLIESLRCLPGVGPKSAQRMAYHLLQRDRSGGMNLARALTEAMSKIGHCEHCRTFTEEDICSICDNPRRQNSRLLCVVEMPADIQAIEQTGQFSGRYFVLMGHLSPLDGIGPREIGLDLLQRRLQQEQFNEVILATNPTVEGDATANYIAELCNQQNIKVSRIAHGIPVGGELETVDGTTLTHSFLGRRTIG
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.