PharMolix/UniProtQA huggingface dataset:
Protein: GRA5_TOXGO
Sequence: MASVKRVVVAVMIVNVLALIFVGVAGSTRDVGSGGDDSEGARGREQQQVQQHEQNEDRSLFERGRAAVTGHPVRTAVGLAAAVVAVVSLLRLLKRRRRRAIQEESKESATAEEEEVAEEE
What is the function of this protein?
Plays a role in the function of the cyst and parasitophorous vacuole membranes and therefore in host-parasite interactions.
What are the official names of this protein?
Dense granule protein 5, Protein GRA 5, p21.
What are the subcellular locations of this protein?
Secreted. Parasitophorous vacuole lumen. Parasitophorous vacuole membrane. Cytoplasmic vesicle, secretory vesicle. Note=Located in dense granules of tachyzoites. Upon infection, secreted into the cyst and the parasitophorous vacuole (PV).
Protein: HPRK_LACLS
Sequence: MAVSVQDLLDKIHFHVIYSTETALQKEITTSEIMRPGLEMAGYFDYFTPERIQLFGMKEWSYMMTVVGDNRYDLLKKVMAKETPVVIVARNLEIPSEMVAAAKKADIVLLQSREATSRLNSVLTSFLDERLAERTTVHGVLMDIFGVGVLIQGASGIGKSETGLELVKRGHRLVADDRVDVFQRDAFTLSGEPAEILRNMIEIRGVGIIDVMSLFGAGAVKDSTDIDMVIYLEYYDKEKAFDRLGNAPTIVEFSDVEVPQTRIPVKTGRNVSVIVEAAVMNFRAKQMGFDATKTFEDRLTDLISHNKESQ
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).  The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc. ) in the growth medium.  Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: VSY1_TRYCO
Sequence: MKRVLSNVLKAWIFTIVAFHNFSTSVTADAPVNAAEYNALCRLYNIARAGEGLKEEDWLPCAGKAACEKTAASIEDVFMKLNFSEPSAVVTTLDGTRVELQNSASTRIKRAKLAKVLAAAETIKAQQLKYHESSKSLLESAKANFTKAIVGGWGNPTTPDESGLPTTFKTNRADDCKLAGGNGGKSLVFDIACLCTTSDSASGSKYTCGPKSGDNGSGWLDNNGDNQGKPAAKEAWKNLRADCRRQSAGVRVTPELISQSLVIFEGLIGTRAASGHDNARYIFGTVATAQSCGHSTATNKGSIDYKASNAQQRGDIEWEKNLRMAEGDLRGLLTAKQLVAALQARAEHLEDAAFTIFNESVLETQIAWESSRPPSTDANTSQKGPLQRPEKSGESSHLPSGSSHGTKAIRSILHVALLM
What is the function of this protein?
VSG forms a coat on the surface of the parasite.  The trypanosome evades the immune response of the host by expressing a series of antigenically distinct VSGs from an estimated 1000 VSG genes.
What are the official names of this protein?
Variant surface glycoprotein YnAT 1.1, VSG.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Note=A soluble form is released from ruptured cells by the action of a PI-PLC.
Protein: RIMP_THEYD
Sequence: MNIKELKDKITDYANIVGEQEGVEIVNVEIYPGGKGLTLRIFIDKEGGVTIKDCENFSRAIEAILDVEDPIKSSYTLEVSSPGIDRPLKNKKDFLRNIGRDVKITTKEKIADNTFFIGKIVDVGDDWVRIEIQETKIKGSKKKGKTELLFIPFNKIIKAQVYLG
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OXLA_NEUCR
Sequence: MKWSAAAGAALLALPANSAVTASLPLKLETRSSLNSRLSNIHVERSASVEGAISYTYGSCQAKREEEAHHSISQPTDAHHDRLVWVIPENVQSGGCISAWSRANGRLVGRSRPQSFDFKSIKMRRDLKARATKPSDSVAIHMTTDNGINPWGPWFDGVKLLEDKEISTVDVEKAKSKNIAIVGAGMSGLMTYLCLTQAGMTNVSIIEGGNRLGGRVHTEYLSGGPFDYSYQEMGPMRFPNTITLGNETYNVSDHQLVFQLAEEMNSLNGHSKNLSVDFIPWYQSNSNGLYYYDGIKNPETGLPPTLAELAANSSLALTRVSNNSTKSLSQKVDAFLPDTDKFFAEMAQNMFKAHADWLSGGLAGLPGDQWSEFGFMVNYLRGSLNDTAFLSASAHSYWDTLYEGMYFSASTWKTIDGGLNRLPLSFHPLVDNATTLNRRVERVAFDAETQKVTLHSRNSYKDSFESSEHDYAVIAAPFSIVKKWRFSPALDLTAPTLANAIQNLEYTSACKVALEFRTRFWEHLPQPIYGSCSTTSDIPGIGSICYPSYNINGTDGPASILASYISGADWGDRWVSTPEEEHVQYVLNAMAEIHGEELVKEQYTGQFNRRCWALDPLESASWASPTVGQHELYLPEYFQTRNNLVFVGEHTSYTHAWIASALESGIRGSVQLLLELGLVDEAKATVDKWMARWIDV
What are the official names of this protein?
L-amino-acid oxidase, LAAO, LAO.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family.
Protein: Y3030_MYCTU
Sequence: MCAFVPHVPRHSRGDNPPSASTASPAVLTLTGERTIPDLDIENYWFRRHQVVYQRLAPRCTARDVLEAGCGEGYGADLIACVARQVIAVDYDETAVAHVRSRYPRVEVMQANLAELPLPDASVDVVVNFQVIEHLWDQARFVRECARVLRGSGLLMVSTPNRITFSPGRDTPINPFHTRELNADELTSLLIDAGFVDVAMCGLFHGPRLRDMDARHGGSIIDAQIMRAVAGAPWPPELAADVAAVTTADFEMVAAGHDRDIDDSLDLIAIAVRP
What is the function of this protein?
Probable S-adenosylmethionine-dependent methyltransferase required for the 6-O-methylation of the polysaccharide backbone of 6-O-methylglucosyl lipopolysaccharides (MGLP).
What are the official names of this protein?
Probable S-adenosylmethionine-dependent methyltransferase Rv3030.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: CLE4C_GLORO
Sequence: MATNTMLCLFVISVVLALAFATNKKGDEEPENHSTGIFGKVGRVVTVALAMSSRLGGADATRGGGAVYGGNLKSNQLPNNNWMAPPPPMAIRSAKVYDSKHSPAEYLKKFAQDFRRKTGMHSQRHHEETTLEQEKRVAGAGPDPIHH
What is the function of this protein?
Mimics host plant CLE extracellular signal peptides that regulate cell fate.  May play a role in the differentiation or division of feeding cells (syncytia) induced in plant roots during infection.
What are the official names of this protein?
CLAVATA3/ESR (CLE)-related protein 4C.
What is the protein family that this protein belongs to?
Belongs to the CLV3/ESR signal peptide family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Host extracellular space. Secreted, extracellular space, apoplast. Note=Present in secretory granules within the dorsal esophageal gland secretory cell and in the dorsal gland ampulla (collecting reservoir) at the base of the nematode stylet. Secreted into host root cells via the nematode stylet to transform the recipient cells into enlarged multinucleate feeding cells called giant-cells or syncytia. Secreted to the host apoplasm from its cytoplasm via a plant secretory pathway (By similarity).
Protein: FER4_ARATH
Sequence: MDQVLYSSYIIKIPVISRISPSQAQLTTRLNNTTYFGLSSSRGNFGKVFAKESRKVKLISPEGEEQEIEGNEDCCILESAENAGLELPYSCRSGTCGTCCGKLVSGKVDQSLGSFLEEEQIQKGYILTCIALPLEDCVVYTHKQSDLI
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
Probable ferredoxin-4, chloroplastic, AtFd4.
What is the protein family that this protein belongs to?
Belongs to the 2Fe2S plant-type ferredoxin family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LEPA_ACIBY
Sequence: MAQAKKSVDIKNIRNFSIIAHIDHGKSTLADRFIQMCGGLQDREMQAQVLDSMELERERGITIKAASVTLYYTHPNGQEYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAAQGVEAQSVANCYTAIEQGLEVLPILNKIDLPQAEPERVIHEIEEIIGIEATNAPTCSAKTGLGVEGVLETLVDVIPAPTGDREAPLQALIIDSWFDNYLGVVSLVRIKDGRIRKGDKMLVKSTGQTHIVTSVGVFNPKHTETGVLEAGEVGFVIAGIKDIFGAPVGDTITLSTTPEVASLPGFKKVKPQVYAGLFPIDASDFEPFREALQKLQINDSALFFEPESSDALGFGFRCGFLGMLHMEIVQERLEREYDLDLISSAPTVVYEAVTKKGDTIYIDSPSKMPDGSVVEDLREPIAECHILVPQEYLGNVMTLCIERRGVQKDMKFLGNQVSITFEIPMAEVVMDFFDKLKSCSRGFASLDYNFIRFESSSLVKVDVLINGEKVDALAMICHRNDARHRGIALVEKMKDLIPRQMFDVAIQAAIGAQIIARSTVKAMRKNVLAKCYGGDVSRKKKLLAKQKEGKKRMKQVGSVEIPQEAFLAVLKVER
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TRMD_AGRFC
Sequence: MTFKATVLTLYPEMFPGHLQYSLAGKALERGQWSLDPIQIREFATDRHRSVDDTPAGGGAGMVLKPDVLAAAIDHVSKGDTRPRLLMSPRGKPLSQNRVRELAAGDGAIIVCGRFEGVDQRVIEARGLEEVSIGDYILSGGEPAALTLLDAVVRILPGVMGNDLSGVHESFEGGLLEHPHYTRPQLWEGRDIPAILTSGNHAAIDKWRHEQALALTKERRPDLLEKTQAETK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPNN_ECO57
Sequence: MITHISPLGSMDMLSQLEVDMLKRTASSDLYQLFRNCSLAVLNSGSLTDNSKELLSRFENFDINVLRRERGVKLELINPPEEAFVDGRIIRALQANLFAVLRDILFVYGQIHNTVRFPNLNLDNSVHITNLVFSILRNARALHVGEAPNMVVCWGGHSINENEYLYARRVGNQLGLRELNICTGCGPGAMEAPMKGAAVGHAQQRYKDSRFIGMTEPSIIAAEPPNPLVNELIIMPDIEKRLEAFVRIAHGIIIFPGGVGTAEELLYLLGILMNPANKDQVLPLILTGPKESADYFRVLDEFVVHTLGENARRHYRIIIDDAAEVARQMKKSMPLVKENRRDTGDAYSFNWSMRIAPDLQMPFEPSHENMANLKLYPDQPVEVLAADLRRAFSGIVAGNVKEVGIRAIEEFGPYKINGDKEIMRRMDDLLQGFVAQHRMKLPGSAYIPCYEICT
What is the function of this protein?
Catalyzes the hydrolysis of the N-glycosidic bond of diverse pyrimidine and purine nucleotide 5'-monophosphates, to form ribose 5-phosphate and the corresponding free base.  Can use AMP, GMP, IMP, CMP, dTMP and UMP as substrates.  Cannot catalyze the reverse reactions.  May contribute to nucleoside pool homeostasis by degrading excess nucleotides and feeding back the ribose moiety to catabolism.
What are the official names of this protein?
Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase, AMP nucleosidase, CMP nucleosidase, GMP nucleosidase, IMP nucleosidase, UMP nucleosidase, dTMP nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the LOG family.
Protein: VAC8_KLULA
Sequence: MGLCCSCLRGESSLEDSTGLPIAENEREAVTSLLEFLENKDQYDFYSGKPLRALTTLVYSDNLNLQRSAALAFAEITEKYVSPVSRDVLEPILMLLTNPDPQIRIASCAALGNLAVNNENKLLIVEMGGLEPLIEQMKSDNVEVQCNAVGCITNLATQDDNKIEIAQSGALVPLTKLARSSNIRVQRNATGALLNMTHSGENRKELVDAGAVPVLVSLLSSMDADVQYYCTTALSNIAVDESNRRYLSKHAPKLVTKLVSLMNSTSPRVKCQATLALRNLASDTNYQLEIVRAGGLPDLVQLIQSDSLPLVLASVACIRNISIHPLNEGLIVDAGFLPPLVKLLDYQESEEIQCHAVSTLRNLAASSEKNRAEFFQSGVIEKFKQLALTCPISVQSEISACFAILALSDNTKYDLLQQDVLKVLIPMTMSQDQEISGNSAAAVANLISRVSNLEKILEYWGQPNDGIKGFLIRFLSSDFPTYEHIALWTILQLFECHNETIYKLIKEDQKLVNGVKKIADENYAVAREYMQDGQDTNIDHNGNSNNIEGNGRSNKQSSEKEDASFELYNITQQIIQFLV
What is the function of this protein?
Functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole.
What are the official names of this protein?
Vacuolar protein 8.
What is the protein family that this protein belongs to?
Belongs to the beta-catenin family.
What are the subcellular locations of this protein?
Vacuole membrane; Lipid-anchor.
Protein: ENO_BIFLO
Sequence: MAVIESVYARQILDSRGNPTVQVVLDTEDGAQGLGLVPSGASTGEAEAWERRDGDKSVYGGKGVLNAVKAVNEVIAPKVIGMDAADQRALDDLMIELDGTPNKGKLGANAILGVSLAALYASAESAGLPLYRYIGGTNGHILPVPNMNIMNGGAHADFATDIQEYMISPYGFDTYSEALRAGVEVYHTLKNVLKKEGLNTGLGDEGGFAPKMKSNEDSLKYIMDAISAAGYEPGKQIGICLDVASSEFYNKETGKYRFDGEERDSAYMLDYYENLINEYPIVSIEDPFNEEGWEDWAAITARLGDRLQFVGDDLLVTNPARLQKAIDLGAANSLLVKLNQIGSVTETLDAIELATANGYTSMVSHRSGETPDTTISDLAVAKNTRQIKTGAPARGERVAKYNRLLEIEEELGSTAQYAGYSAFKACKKYLAK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: DIF1_YEAS8
Sequence: MDAQLEWASSLVPKRQLQQQQQQQEQQQQQQQDFHKDQLMTVGMRIRQRVDQGYASRTPSTSDASLQPGVIRDYSSVIVPQFTRSPLPTANSLPPMLINQRTMSTEASSLEKWDVAEPAAEHEAMVNGSKRRL
What is the function of this protein?
Mediates the nuclear localization of RNR2 and RNR4, 2 subunits of the ribonucleotide reductase.
What are the official names of this protein?
Damage-regulated import facilitator 1.
What is the protein family that this protein belongs to?
Belongs to the DIF1/spd1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GSA_SHEFN
Sequence: MTRSEVLFEQAKKTIPGGVNSPVRAFNGVGGSPLFIEKADGAYIFDADGKKYIDYVGSWGPMILGHNHPKIRQAVLDAVDNGLSFGAPTELEVKMAEKVISMVPSIEQVRMVSSGTEATMSAIRLARGFTNRDNILKFEGCYHGHADCLLVKAGSGALTLGQPSSPGIPEDFAKHTLTATYNDLDSVRAIFEQNPESIACIILEPVAGNMNCIPPVEGFLQGLRTICDEFGALLIIDEVMTGFRVSMSGAQGHYGVTPDLTTLGKVIGGGMPVGAFGGRKDVMQFIAPTGPVYQAGTLSGNPIAMSAGLAQMDALCEPGLYEALADKTKRVAEGFKAAADKHGIPLNITYVGGMFGFFFTEDNTPMTSFAQVTKCNMEHFRHFYHAMLDEGIYLAPSAYEAGFMSMAHGDAEIEYTLAAVDRIFAAMK
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCHS_RAT
Sequence: MMEPSEYHEYQARGKEMVDYICQYLSTVRERQVTPNVKPGYLRAQIPSSAPEEPDSWDSIFGDIEQIIMPGVVHWQSPHMHAYYPALTSWPSLLGDMLADAINCLGFTWASSPACTELEMNIMDWLAKMLGLPDFFLHHHPSSQGGGVLQRTVSESTLIALLAARKNKILEMKAHEPNADESSLNARLVAYASDQAHSSVEKAGLISLVKIKFLPVDDNFSLRGEALQKAIEEDKQQGLVPVFVCATLGTTGVCAFDKLSELGPICAREGLWLHVDAAYAGTAFLRPELRGFLKGIEYADSFTFNPSKWMMVHFDCTGFWVKDKYKLQQTFSVNPIYLRHANSGVATDFMHWQIPLSRRFRSIKLWFVIRSFGVKNLQAHVRHGTDMAKYFESLVRSDPVFEIPAERHLGLVVFRLKGPNCLTESVLKEIAKTGQVFLIPATIQDKLIIRFTVTSQFTTKDDILRDWNLIREAANLVLSQHCTSQPSPRAKNLIPPPVTRDSKDLTNGLSLESVNEGGDDPVQVRKIFRLPGDSLETTMDPFDDCFSEEASDTTKHKLSSFLFSYLSVQNKKKTMRSLSCNSMPMSAQKSPPPDASVKHGGFFRARIFSGFPEEMMMMKKGGFKKLIKFYSVPSFPECSSQCGTLQLPCCPLQAMV
What is the function of this protein?
Catalyzes the biosynthesis of histamine from histidine.
What are the official names of this protein?
Histidine decarboxylase, HDC.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
Protein: RL4_CORGB
Sequence: MTNLKLDVQTADGNINGSVELPAEIFDREVSVALLHQVVNAQLAAARQGTHSTKTRGEVRGGGRKPFRQKGTGRARQGSIRAPHFTGGGISHGPKPRDYSQRTPKKMIKAALYGALSDRARNARIHVVSELVPGQTPSTKSAKAFIERLTERKSVLLVVSREDINAQKSANNLPGVHILAADQLNTYDVLKSDDVVFSVEALHTFINRASGAAQEEQN
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: CH602_SALRD
Sequence: MAKQIKFDSDARSALQEGVDQMAKAVKVTLGPKGRNVVLEKSFGAPTITKDGVTVAKEIELEERLPNIGAQVLKEAASKTNDDAGDGTTTATVLAQSVINAGMKSVTSGANPMDVKRGITAAAEEVVTHLRNQSDPVEGKDRISQVATISANNDDAIGDLIADAFERVGQDGVITVEEARGIETYLDVVEGMQFDRGYLSPYFVTDSEEMEAVLEDAYILIYDDEVGNMQDLLPILEKVSQTSNPLLIIAEDVEGEALATLVVNKMRGTLKVSAVKAPGFGDRRQSMLEDIAVLTGGTVISEEKGYRLENATLDYLGQADRVTIDQDNTTIVGGEGSEEEIEARVNQIRQQIANSTSDYDQEKLQERLAKLAGGVAVLNVGAATEPEMKAQKALVEDALSATRAAVDEGVLPGGGVAYLRALESIEEVEVENEDQEIGVSIVREALEAPLRQIAENTGHEGSIVVQKVKDGEGDFGFNARTEEYGDLLDQGVLDPTKVTRSALENAASVGGMLLTTEAVIADLEDEDDDDGGGGGGGGMPAGGAGGMGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPA_STRPF
Sequence: MKKTYRVKREKDFQAIFKDGKSTANRKFVIYHLNRGQDHFRVGISVGKKIGNAVTRNAVKRKIRHVIMALGHQLKSEDFVVIARKGVESLEYQELQQNLHHVLKLAQLLEKGFESEEKH
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: DCAF1_HUMAN
Sequence: MTTVVVHVDSKAELTTLLEQWEKEHGSGQDMVPILTRMSQLIEKETEEYRKGDPDPFDDRHPGRADPECMLGHLLRILFKNDDFMNALVNAYVMTSREPPLNTAACRLLLDIMPGLETAVVFQEKEGIVENLFKWAREADQPLRTYSTGLLGGAMENQDIAANYRDENSQLVAIVLRRLRELQLQEVALRQENKRPSPRKLSSEPLLPLDEEAVDMDYGDMAVDVVDGDQEEASGDMEISFHLDSGHKTSSRVNSTTKPEDGGLKKNKSAKQGDRENFRKAKQKLGFSSSDPDRMFVELSNSSWSEMSPWVIGTNYTLYPMTPAIEQRLILQYLTPLGEYQELLPIFMQLGSRELMMFYIDLKQTNDVLLTFEALKHLASLLLHNKFATEFVAHGGVQKLLEIPRPSMAATGVSMCLYYLSYNQDAMERVCMHPHNVLSDVVNYTLWLMECSHASGCCHATMFFSICFSFRAVLELFDRYDGLRRLVNLISTLEILNLEDQGALLSDDEIFASRQTGKHTCMALRKYFEAHLAIKLEQVKQSLQRTEGGILVHPQPPYKACSYTHEQIVEMMEFLIEYGPAQLYWEPAEVFLKLSCVQLLLQLISIACNWKTYYARNDTVRFALDVLAILTVVPKIQLQLAESVDVLDEAGSTVSTVGISIILGVAEGEFFIHDAEIQKSALQIIINCVCGPDNRISSIGKFISGTPRRKLPQNPKSSEHTLAKMWNVVQSNNGIKVLLSLLSIKMPITDADQIRALACKALVGLSRSSTVRQIISKLPLFSSCQIQQLMKEPVLQDKRSDHVKFCKYAAELIERVSGKPLLIGTDVSLARLQKADVVAQSRISFPEKELLLLIRNHLISKGLGETATVLTKEADLPMTAASHSSAFTPVTAAASPVSLPRTPRIANGIATRLGSHAAVGASAPSAPTAHPQPRPPQGPLALPGPSYAGNSPLIGRISFIRERPSPCNGRKIRVLRQKSDHGAYSQSPAIKKQLDRHLPSPPTLDSIITEYLREQHARCKNPVATCPPFSLFTPHQCPEPKQRRQAPINFTSRLNRRASFPKYGGVDGGCFDRHLIFSRFRPISVFREANEDESGFTCCAFSARERFLMLGTCTGQLKLYNVFSGQEEASYNCHNSAITHLEPSRDGSLLLTSATWSQPLSALWGMKSVFDMKHSFTEDHYVEFSKHSQDRVIGTKGDIAHIYDIQTGNKLLTLFNPDLANNYKRNCATFNPTDDLVLNDGVLWDVRSAQAIHKFDKFNMNISGVFHPNGLEVIINTEIWDLRTFHLLHTVPALDQCRVVFNHTGTVMYGAMLQADDEDDLMEERMKSPFGSSFRTFNATDYKPIATIDVKRNIFDLCTDTKDCYLAVIENQGSMDALNMDTVCRLYEVGRQRLAEDEDEEEDQEEEEQEEEDDDEDDDDTDDLDELDTDQLLEAELEEDDNNENAGEDGDNDFSPSDEELANLLEEGEDGEDEDSDADEEVELILGDTDSSDNSDLEDDIILSLNE
What is the function of this protein?
(Microbial infection) In case of infection by HIV-2 virus, it is recruited by HIV-2 Vpx in order to hijack the CUL4A-RBX1-DDB1-DCAF1/VPRBP function leading to enhanced efficiency of macrophage infection and promotion of the replication of cognate primate lentiviruses in cells of monocyte/macrophage lineage.
What are the official names of this protein?
DDB1- and CUL4-associated factor 1, HIV-1 Vpr-binding protein, VprBP, Serine/threonine-protein kinase VPRBP, Vpr-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the VPRBP/DCAF1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Associated with chromatin in a DDB1-independent and cell cycle-dependent manner: recruited to chromatin as DNA is being replicated and is released from chromatin before mitosis.
Protein: HEMA_VACCW
Sequence: MTRLPILLLLISLVYATPFPQTSKKIGDDATLSCNRNNTNDYVVMSAWYKEPNSIILLAAKSDVLYFDNYTKDKISYDSPYDDLVTTITIKSLTARDAGTYVCAFFMTSTTNDTDKVDYEEYSTELIVNTDSESTIDIILSGSTHSPETSSKKPDYIDNSNCSSVFEIATPEPITDNVEDHTDTVTYTSDSINTVSASSGESTTDETPEPITDKEDHTVTDTVSYTTVSTSSGIVTTKSTTDDADLYDTYNDNDTVPPTTVGGSTTSISNYKTKDFVEIFGITALIILSAVAIFCITYYIYNKRSRKYKTENKV
What is the function of this protein?
Prevents cell to cell fusion by interacting with and directing the viral OPG040 protein on the host plasma membrane.  The OPG185-OPG040 complex associates with components of the entry fusion complex (EFC) presumably to avoid superinfection and syncytium formation.  Via its interaction with C3/VCP protein, protects the infected cell and probably also the extracellular enveloped virus from complement attack.
What are the official names of this protein?
Protein OPG185, Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG185 family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host membrane; Single-pass type I membrane protein. Note=Component of extracellular enveloped virus (EEV) but not intracellular mature virus (IMV). Component of the outermost membrane of EEV.
Protein: RL4_BACC2
Sequence: MPKVTVYNQTGSQVGEIELAEAIFGIEPNEAVLFEAVMMQRASLRQGTHKVKTRSEVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGTVFGPTPRSYAYKLPKKVRRLAIKSALATKVVENNIVVLEDLVLNAPKTKDMLAVLKGLTVEKKALIVTADANESVELSARNIPGVTVITADGVNVLDVLHHDKLIMTKAAVEKVEEVLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: DNAK_ACICA
Sequence: AKIIGIDGLTTNSWVAVLESDKVHV
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: SYSC_CAEEL
Sequence: MVLDIDMFRTEKGGNPEIIRKSQQDRFKDPKLVDEVIELDEKWRKERFVADQLNRQKNAISKAIGEKMKKKEPQGTDDSVADDIVARLAELKIDELSQLTVVQLKKLRVLVDEKSVQTAAAVIANENARHEKLIQIGNLIHSSVVVSKDEANNKIERTFGDLSTKKKYSHVDLVVMVDGFDGERGTVVAGGRGYFLKGPLVFLEQAIIQLALQRLNVKGYVPLYTPFFMRKEVMQEVAQLSQFDDELYKVSSKGSEIAGDTSVDEKYLIATSEQPIAAYHRNEWIKETELPIKYAGVSTCFRQEVGSHGRDTRGIFRVHQFEKIEQFVLCSPNDNESWTLFDEMIGNAESYYQELQIPYQVVNIVSGELNNAAAKKFDLEAWFPGSGAYRELVSCSNCLDYQSRRLKVRYGQTKKLSGEVPFVHMLNATMCATTRVICAILENNQTEEGINVPTAIQQWMPENYRTFIPFVKPAPIDEDAKKATGKK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity).
What are the official names of this protein?
Probable serine--tRNA ligase, cytoplasmic, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y377_MYCTO
Sequence: MTPAQLRAYSAVVRLGSVRAAAAELGLSDAGVSMHVAALRKELDDPLFTRTGAGLAFTPGGLRLASRAVEILGLQQQTAIEVTEAAHGRRLLRIAASSAFAEHAAPGLIELFSSRADDLSVELSVHPTSRFRELICSRAVDIAIGPASESSIGSDGSIFLRPFLKYQIITVVAPNSPLAAGIPMPALLRHQQWMLGPSAGSVDGEIATMLRGLAIPESQQRIFQSDAAALEEVMRVGGATLAIGFAVAKDLAAGRLVHVTGPGLDRAGEWCVATLAPSARQPAVSELVGFISTPRCIQAMIPGSGVGVTRFRPKVHVTLWS
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator MT0391.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.