PharMolix/UniProtQA huggingface dataset:
Protein: AT2C1_BOVIN
Sequence: MDNLLPQSRFSYFKKYPIHAIRKYLSMLRNQKEEEQVARFQKIPNAENETMIPVLTSKKASELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLMPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSVDESSLTGETTPCSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGIVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLRAEVTGVGYNPFGEVIVDGDVVHGFYNPSVSRIVEAGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTYHSKGQTLTLTQQQRDLYQQEKAQMGSAGLRVLALASGPELGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQSVSGEEIDAMDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSIIIVCGTLFVFWRELRDNVITPRDTTMTFTCFVFFDMFNALSSRSQTKSVFEIGLCSNKMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDLLFLLGLTSSVCIVAEIIKKVERSREKIQKPVSSTSSSFLEV
What is the function of this protein?
ATP-driven pump that supplies the Golgi apparatus with Ca(2+) and Mn(2+) ions, both essential cofactors for processing and trafficking of newly synthesized proteins in the secretory pathway (By similarity).  Within a catalytic cycle, acquires Ca(2+) or Mn(2+) ions on the cytoplasmic side of the membrane and delivers them to the lumenal side.  The transfer of ions across the membrane is coupled to ATP hydrolysis and is associated with a transient phosphorylation that shifts the pump conformation from inward-facing to outward-facing state (By similarity).  Plays a primary role in the maintenance of Ca(2+) homeostasis in the trans-Golgi compartment with a functional impact on Golgi and post-Golgi protein sorting as well as a structural impact on cisternae morphology.  Responsible for loading the Golgi stores with Ca(2+) ions in keratinocytes, contributing to keratinocyte differentiation and epidermis integrity (By similarity).  Participates in Ca(2+) and Mn(2+) ions uptake into the Golgi store of hippocampal neurons and regulates protein trafficking required for neural polarity (By similarity).  May also play a role in the maintenance of Ca(2+) and Mn(2+) homeostasis and signaling in the cytosol while preventing cytotoxicity (By similarity).
What are the official names of this protein?
Calcium-transporting ATPase type 2C member 1, ATPase 2C1, ATP-dependent Ca(2+) pump PMR1, Ca(2+)/Mn(2+)-ATPase 2C1, Secretory pathway Ca(2+)-transporting ATPase type 1, SPCA1.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Golgi apparatus, Golgi stack membrane; Multi-pass membrane protein. Note=During neuron differentiation, shifts from juxtanuclear Golgi position to multiple Golgi structures distributed over the neural soma with a predominance in the apical dendritic trunk.
Protein: KTHY_DESPS
Sequence: MSNNPGKLIIFEGTDGAGKSTQIKMLANYLRSKGLDVIASFEPTNGPYGQKIRQLYTDRNKVTRNEELELFLADRREHVNKLINPAISAGKIVLCDRYYLSTAAYQGALGFDVEEILQRNSFAPTPDLALLLQIPVEDGRRRITSSRGEETNDFEKAEMLEKVSTIFNSLSFPYIRHINACQSIDNVQRDIIMQVKQLLKMA
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: RL15_PIG
Sequence: GYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVXEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNC_SHESM
Sequence: MEPIKNLPRLCRTLGYEFKNIELLTQALTHRSAANKHNERLEFLGDSILSIVISDALYHQFPKATEGDLSRMRATLVRGDTLTLIAKAFKLGDYLFLGPGELKSGGFRRESILADAVEAIIGAIYLDSDLEVCRKLLLHWYAERLAEIQPGVNQKDAKTLLQEYLQGLKKPLPDYQVINIEGDAHDQTFTVECRIDDLSESVIGVASSRRKAEQIAAAQVLELLKK
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCD_WOLSU
Sequence: MGLKEDRWITDMALPHNMIEPFCENQVGKNVVSYGLSSYGYDIRVSNEFKIFTNINATVVDPKNFDEANVVDFIGDICIVPPNSFALARTVEYFRIPRDVLAICLGKSTYARCGIIVNVTPFEPEFEGHITIEISNTTPLPAKIYANEGIAQVLFLQGDADCEVSYKDKKGKYQKQEGITLPRILK
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: CHEA_ECOLI
Sequence: MSMDISDFYQTFFDEADELLADMEQHLLVLQPEAPDAEQLNAIFRAAHSIKGGAGTFGFSVLQETTHLMENLLDEARRGEMQLNTDIINLFLETKDIMQEQLDAYKQSQEPDAASFDYICQALRQLALEAKGETPSAVTRLSVVAKSEPQDEQSRSQSPRRIILSRLKAGEVDLLEEELGHLTTLTDVVKGADSLSAILPGDIAEDDITAVLCFVIEADQITFETVEVSPKISTPPVLKLAAEQAPTGRVEREKTTRSNESTSIRVAVEKVDQLINLVGELVITQSMLAQRSSELDPVNHGDLITSMGQLQRNARDLQESVMSIRMMPMEYVFSRYPRLVRDLAGKLGKQVELTLVGSSTELDKSLIERIIDPLTHLVRNSLDHGIELPEKRLAAGKNSVGNLILSAEHQGGNICIEVTDDGAGLNRERILAKAASQGLTVSENMSDDEVAMLIFAPGFSTAEQVTDVSGRGVGMDVVKRNIQKMGGHVEIQSKQGTGTTIRILLPLTLAILDGMSVRVADEVFILPLNAVMESLQPREADLHPLAGGERVLEVRGEYLPIVELWKVFNVAGAKTEATQGIVVILQSGGRRYALLVDQLIGQHQVVVKNLESNYRKVPGISAATILGDGSVALIVDVSALQAINREQRMANTAA
What is the function of this protein?
Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors.  CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.
What are the official names of this protein?
Chemotaxis protein CheA.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS7_CERS5
Sequence: MRQADITRKTAETAISVKVDLDGTGRYDIRTGVGFFDHMMDQLARHSLIDITLRCEGDLHIDDHHTVEDCGIALGQALTQALGDKRGIRRYGSFHLAMDDALVRCALDLSGRPYLVCNLPFPAAKIGSFDTELVREFFQALSTHGGITLHLDLIHGLNGHHIAEAAFKAVARSLREAVEPDPRAASAIPSTKGML
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURD_SYNS9
Sequence: MTLTIVVGLGRSGLGAARLLHHQGQKVVVLERGTGPDQTSCAATLQAEGIQVELGIPLEINSFEPWRSDLDAVVVGPGIPWDHPTLNGLRQEGVQIRGEIELAWEALNDIPWVGITGTNGKTTVTHLLSHVLGHAGIVAPMGGNMGVSAADMALKIRRGETPKPDWLVMELSSYQIEAGPNLAPSIGIWTTLTPDHLERHGTLEAYRAIKHSLLQRSSLAIFNGDDADLSAHRPSLKRGMWVKAAPPCHDDPPADFWIDDAGTVQAREGGAMFPAKVLAMPGAHNRQNLLLVTAAAAQIGLNAEQIAQGLESFPGVPHRLENLGSTSSADVFNDSKATNYDAAAVGLQAMAGPVVVLAGGQTKRGNATGWLAELKSKACAVVLFGAGAEELDALIRQSNYQGQVHRCTDLSAAVAIAVRATSELQASSLLLSPACASFDQYQDFEARGDHFRDLMQPHMHVG
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PBPF_BACSU
Sequence: MFKIKKKKLFIPIIILVLTAFLALIGYISIIFLGHYVIDEKKLILHASSKIVDQNGDEVASLYTENREPVSINEIPKQVREAFIAVEDKRFYEHHGIDAKSVGRAVYRDILAGGKVEGGSTITQQLAKNIFLTHDKTFLRKTKEVIIAINLERDYSKDKLLEMYLNQLYFGHGVYGIQAASHYYFNKEVKDLTVSEGAVLAAIPKAPSTYSPILHPDKNKERRDTILGMMNDQGYISAKEAVTAQGRTLGLHVKKQSETPWFDSYIDLVIKEAEDKYSISGEQLLQGGYTIKVPLDSKLQKTAYQVMKEGSYYPGTDQNAEGSAVFINNKTGGVEAAIGGRDYTSKGYNRVTAVRQPGSTFKPLAVYGPAMQEKKFKPYSLLKDELQSYGDYTPKNYDSRYEGEVTMSDAITYSKNAPAVWTLNEIGVETGKSYLKANGIDIPDEGLALALGGLEKGVSPLQLAGAFHTFAANGTYTEPFFISSIIDEDGETIADHKEEGKRVFSKQTSWNMTRMLQQVVKKGTATSGTYHGDLAGKTGSTSYTGVSGATKDAWFAGYTPKITGAVWMGYDKTDQNHYLKAGSSYPTRLFKDILTQAGETGHVFTKPKNVKELESPIELKPVKTLTADYTFKAAGLFTIELKWDAQEDDRAVYRIYVNKDGEETLLDSVEGKGSYEIPYANLFSGASYKIVPYNTQTKREGEGTDYVQPKLFSS
What is the function of this protein?
Cell wall formation.  May be involved in outgrowth of the germinated spore or it could function in the synthesis of the germ cell wall.
What are the official names of this protein?
Penicillin-binding protein 1F, PBP-1F, Penicillin-binding protein F.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transpeptidase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: APT_XANCB
Sequence: MNDCSRCAGSTSSGPTHWSGRIRDIADFPKPGIVFKDITPLLSDGPDFASALDEMAQPWRTTPLDAVLGIEARGFILGAALARELRTGFVPVRKPGKLPGRTLIQEYALEYGTDRIEMHEDALPRGARVLIVDDVLATGGTLRAALGLAAQLELEIVGAAVLVELLALQGRSKWLNDVPLLATLSY
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZG16_RAT
Sequence: MLAIALLVLLCASASANSIQSRSSSYSGEYGGKGGKRFSHSGNQLDGPITAIRIRVNRYYIIGLQVRYGTVWSDYVGGNQGDLEEIFLHPGESVIQVSGKYKSYVKQLIFVTDKGRYLPFGKDSGTSFNAVPLHPNTVLRFISGRSGSAIDAISLHWDTYPSHCNTC
What is the function of this protein?
May play a role in protein trafficking.  May act as a linker molecule between the submembranous matrix on the luminal side of zymogen granule membrane (ZGM) and aggregated secretory proteins during granule formation in the TGN.
What are the official names of this protein?
Zymogen granule membrane protein 16, Zymogen granule protein 16, Secretory lectin ZG16.
What is the protein family that this protein belongs to?
Belongs to the jacalin lectin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Zymogen granule lumen. Golgi apparatus lumen.
Protein: KCNQ4_MOUSE
Sequence: MAEAPPRRLGLGPPPGDAPRAELVALTAVQSEQGEAGGGGSPRRLGLLGSPLPPGAPLPGPGSGSGSACGGQRSSAAQKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIIRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRLYSTDTSRAYLTATWYYYDSILPSFRELALLFEHIQRARNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSASFCPGESSRMGIKDRIRISSSQKRTGPSKQHLAPPPIPTSPSSEQVGEASSPSKVQKSWSFNDRTRFRASLRLKPRCSAEEGPSEEVAEEKSYQCELTVDDVMPAVKTVIRSVRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQARVDQIVGRGPGDRKTREKGDKGPSDTEAVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGTVQVPLFDPDITSDYHSPVDHEDISVSAQTLSISRSVSTNMD
What is the function of this protein?
Probably important in the regulation of neuronal excitability.  May underlie a potassium current involved in regulating the excitability of sensory cells of the cochlea.
What are the official names of this protein?
Potassium voltage-gated channel subfamily KQT member 4, KQT-like 4, Potassium channel subunit alpha KvLQT4, Voltage-gated potassium channel subunit Kv7.4.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. KQT (TC 1.A.1.15) subfamily. Kv7.4/KCNQ4 sub-subfamily.
What are the subcellular locations of this protein?
Basal cell membrane; Multi-pass membrane protein. Note=Situated at the basal membrane of cochlear outer hair cells.
Protein: JZT22_CHIGU
Sequence: MKTSVLLVILGIAAITVQCTASESVEQDSLRTFVDAVLGWNAEMASEARCGGWMAKCADSDDCCEAFHCTRFNVCGK
What is the function of this protein?
Probable ion channel inhibitor.
What are the official names of this protein?
U14-theraphotoxin-Cg1b, U14-TRTX-Cg1b, Jingzhaotoxin-22, JZTX-22.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 65 (Jztx-21) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GUAA_PSEU2
Sequence: MALDIHAHRILILDFGSQYTQLIARRVREIGVYCELHPFDMDDEAIREFAPKGVVLAGGPESVHEADSPRCPQAVFDLGVPVFGICYGMQTMAEQLGGKVAGSELREFGYARVDVVGKSRLLDGIEDHIDADGLFGLDVWMSHGDKVTKLPENFHILASTPSCPIAGMADDARGYYGVQFHPEVTHTKQGGRILSRFILDICGCEALWTPSKIAEDAIAQVRAQVGTDNVLLGLSGGVDSSVVAALLHKAIGDQLTCVFVDNGLLRLHEGEQVMAMFAENMGVKVIRANAEEQFLNNLAGESDPEKKRKIIGRTFIDVFDAESCKLDNIKYLAQGTIYPDVIESAGAKSGKAHVIKSHHNVGGLPEEMNLKLVEPLRELFKDEVRRLGLELGLPYDMVYRHPFPGPGLGVRILGEVKKEYADLLRRADHIFIEELRKADWYHKVSQAFVVFQPVKSVGVVGDGRRYAWVVALRAVETIDFMTARWAHLPYELLETVSGRIINEIEGISRVTYDVSSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: DXS_DEHMC
Sequence: MNTGLEISILHNLEMSKLLDTINSPSDLKKLSLDELRELAVQIREELVNRVTLNGGHLASSLGVVELTIALHRVFESPKDKIIWDVGHQSYAHKLLTGRREQFATLRQHGGLSGFTCRDESPHDPFGAGHASTSISAGLGMAVARDLAKEDYSVISVIGDGAISGGMSFEAINNAGHLHTKFIVILNDNGMAISPSTGALSKFLNNVRFDPRFEFAKRNAKQTITNMPFGKAVWAFTKSIKRKFEKSMLPGSLWEELGFIYLGPVDGHNIRELEAALKRAKDFESKPVLIHMITKKGKGYDDAEADAVKYHGISPKSGGLKSSHGLSYSQVFGQTLHKIMSQNPQVVAITAAMTDGCGLGEIAAAFPDRVFDVGICEQHAVTFAAGMATQGYIPVVVIYSTFLQRGFDQIIHDVCLQKLPVVFAIDRGGIVGDDGKTHQGIFDLSFMSLIPDMVVSAPSDENDLQHLIYTAVNSGKPFALRYPRGFGEGAEIESSLHNIPIGQNEILVNGSDVAILATGKSVAFAKDALEILTESGIKPTLVNNRYISPLDSELVLKIAQSHKYLVTVEENVISGGLGSRINTLLAEAGLVNKIKIANIGIPDKFVEHGNQSLLRAKYGLDGKGIAQRVLSLVGNPNEMKHPQIICP
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: DTX19_ARATH
Sequence: MADPATSSPLLDDHVGGEDERGRRSRSSTLVQKVIDVEEAKAQMIYSLPMILTNVFYYCIPITSVMFASHLGQLELAGATLANSWATVSGFAFMVGLSGSLETLCGQGFGAKRYRMLGVHLQSSCIVSLVFSILITIFWFFTESIFGLLRQDPSISKQAALYMKYQAPGLLAYGFLQNILRFCQTQSIIAPLVIFSFVPLVINIATAYVLVYVAGLGFIGAPIATSISLWIAFLSLGTYVMCSEKFKETWTGFSLESFRYIVINLTLSLPSAAMVCLEYWAFEILVFLAGVMPNPEINTSLVAICVNTEAISYMLTYGLSAAASTRVSNELGAGNVKGAKKATSVSVKLSLVLALGVVIVLLVGHDGWVGLFSDSYVIKEEFASLRFFLAASITLDSIQGVLSGVARGCGWQRLVTVINLATFYLIGMPIAAFCGFKLKFYAKGLWIGLICGIFCQSSSLLLMTIFRKWTKLNVATV
What is the function of this protein?
Required for protection of the roots from inhibitory compounds.  When expressed in a heterologous system, confers resistance to tetramethylammonium chloride.
What are the official names of this protein?
Protein DETOXIFICATION 19, AtDTX19, Multidrug and toxic compound extrusion protein 19, MATE protein 19, Protein ABERRANT LATERAL ROOT FORMATION 5.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NORW_SALPA
Sequence: MSRGIIIIGSGFAARQLVKNIRKQDAHVPLTLIAADSMDEYNKPDLSHVISQSQRADDLTRQLAGEFAEQFNLRLFPHTWVTDIDADAHVVKSQDKQWQYDKLVLATGAAAFVPPIAGRELMLTLNNQQEYRACETPLRDAQRVLIVGGGLIGSELAMDFCRAGKTVTLMDNAASLLASLMPPEVSSRLQHHLTDMGVHLLLKSQLQKLEKIEAGIRATLASQRSIEVDAVIAATGLRPETALARRAGVVVNRGVCVDSYLQTSHPDIYAIGDCAEINGQVLPFLQPIQLSAMYLAKNLLGGNAPLKLPAMLVKVKTPELPLHLAGETQRRDLSWQITAESDGMIAKGMSGEGQLRAFVVSEDRMKEAFALLKTLSV
What is the function of this protein?
One of at least two accessory proteins for anaerobic nitric oxide (NO) reductase.  Reduces the rubredoxin moiety of NO reductase.
What are the official names of this protein?
Nitric oxide reductase FlRd-NAD(+) reductase, Flavorubredoxin reductase, FlRd-reductase, FlavoRb reductase.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_STRP8
Sequence: MAKDIKFSADARAAMVRGVDMLADTVKVTLGPKGRNVVLEKAFGSPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVHEGLKNVTAGANPIGIRRGIETATATAVEALKAIAQPVSGKEAIAQVAAVSSRSEKVGEYISEAMERVGNDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDNEKMVADLENPFILITDKKVSNIQDILPLLEEVLKTNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKAPGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATMTALGQAAKITVDKDSTVIVEGSGSSEAIANRIALIKSQLETTTSDFDREKLQERLAKLAGGVAVIKVGAPTETALKEMKLRIEDALNATRAAVEEGIVAGGGTALITVIEKVAALELEGDDATGRNIVLRALEEPVRQIALNAGYEGSVIIDKLKNSPAGTGFNAATGEWVDMIKTGIIDPVKVTRSALQNAASVASLILTTEAVVANKPEPAAPAPAMPAGMDPGMMGGF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCIB_HAEDU
Sequence: MKQLLEFIPLILFFAVYKLVGVQAAAITLVLATILQLILVRILFKKLETSQWIVGLSVIIFGILTAYFDDLAFLKWKVTIINGLFAAVLLISQYVFHKPVVKMLLAKELSLPTQVWNRLNLGWAIFFIICMLINIIISQLFSDDTWATFKTFGFTGLSLVAVIITGIYLYPYIKKLENNNEQK
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GAL1_LACPL
Sequence: MNTSDLKQEFTEAFDTKPERVFFSPGRINLIGEHTDYNGGHVFPCAITIGTYGVYAPRTDTTVRMYSANIPDAGIVTFDVNDLSYDKAAGWTNYPKGMMDEIAKTGVKFDHGFDFYVHGNMPDGAGLSSSASIELLTGIMLNTGFNLGISQLDLVKIGQKCENNYVGVNSGIMDQFAVGMGKKDQAILLDTNTMDYSYAPVKLGNNVIVIMNTNKRRELADSKYNERRSECEEALRRLQTKLDIKSLGDLTNDQFDEAAYLINDETLIKRARHAVFENQRAIRATKALADDDLTTFGELVTASHVSLHFDYEVTGKELDTLAETAWKQPGVLGARMTGAGFGGCGIAIVDKDQVDAFKENVGKVYRDTIGYDADFYIAEIADGPKEL
What is the function of this protein?
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_THEP1
Sequence: MPKMKTNRSAAKRFRITKNGKIMRNHAYRSHKTGKKRRNTLRELRKKDVVSSTDKYRILRLLGKK
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: SCRB2_RAT
Sequence: MARCCFYTAGTLSLLLLVTSVTLLVARVFQKAVDQTIEKNMVLQNGTKVFDSWEKPPLPVYIQFYFFNVTNPEEILQGEIPLLEEVGPYTYRELRNKANVQFGENGTTISAVTNKAYIFERNQSVGDPTVDLIRTINIPLLTVVEMAQQPFLREIIEAMLKAYQQTLFVTHTVHELLWGYKDEVLSLVHIFRPDVSPNFGLFYERNGTNDGEYVFLTGEDNYLNFTKIVEWNGKTSLDWWTTDTCNMINGTDGDSFHPLISKDETLYIFPSDFCRSVYITFSSFENVEGLPAFRYKVPAEILANSSENAGFCIPEGNCMDAGVLNVSICKNGAPIIMSFPHFYQADEKFVSAIKGMRPNKEEHESFVDINPLTGIILRGAKRFQINTYVKKLDDFVETGNIRTMVFPVMYLNESVLIDKETASQLKSVINTTLIVTNIPYIIMALGVFFGLIFTWLACRGQGSTDEGTADERAPLIRT
What is the function of this protein?
Acts as a lysosomal receptor for glucosylceramidase (GBA1) targeting.
What are the official names of this protein?
Lysosome membrane protein 2, 85 kDa lysosomal membrane sialoglycoprotein, LGP85, CD36 antigen-like 2, Lysosome membrane protein II, LIMP II, Scavenger receptor class B member 2.
What is the protein family that this protein belongs to?
Belongs to the CD36 family.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein.
Protein: RS7_LACH4
Sequence: MPRKGHVTKRAVLADPVYNSKLVTKLINHLMIDGKRAKASSILYDAFNIVQDKTGKEPLDVFEEAMNNVMPVLEVRARRIGGSNYQIPVEVRPERRTTLGLRWLVSYARLRNEHTMDERLANEIIDASNNTGSAVKKREDVHRMAEANRAFAHYRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: GFPT2_HUMAN
Sequence: MCGIFAYMNYRVPRTRKEIFETLIKGLQRLEYRGYDSAGVAIDGNNHEVKERHIQLVKKRGKVKALDEELYKQDSMDLKVEFETHFGIAHTRWATHGVPSAVNSHPQRSDKGNEFVVIHNGIITNYKDLRKFLESKGYEFESETDTETIAKLIKYVFDNRETEDITFSTLVERVIQQLEGAFALVFKSVHYPGEAVATRRGSPLLIGVRSKYKLSTEQIPILYRTCTLENVKNICKTRMKRLDSSACLHAVGDKAVEFFFASDASAIIEHTNRVIFLEDDDIAAVADGKLSIHRVKRSASDDPSRAIQTLQMELQQIMKGNFSAFMQKEIFEQPESVFNTMRGRVNFETNTVLLGGLKDHLKEIRRCRRLIVIGCGTSYHAAVATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFFISQSGETADTLLALRYCKDRGALTVGVTNTVGSSISRETDCGVHINAGPEIGVASTKAYTSQFISLVMFGLMMSEDRISLQNRRQEIIRGLRSLPELIKEVLSLEEKIHDLALELYTQRSLLVMGRGYNYATCLEGALKIKEITYMHSEGILAGELKHGPLALIDKQMPVIMVIMKDPCFAKCQNALQQVTARQGRPIILCSKDDTESSKFAYKTIELPHTVDCLQGILSVIPLQLLSFHLAVLRGYDVDFPRNLAKSVTVE
What is the function of this protein?
Controls the flux of glucose into the hexosamine pathway.  Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2, D-fructose-6-phosphate amidotransferase 2, Glutamine:fructose-6-phosphate amidotransferase 2, GFAT 2, GFAT2, Hexosephosphate aminotransferase 2.
Protein: NUOH_CUPTR
Sequence: MIDWITSQGQGVLGAYWTPLWILIRAVIIVVPLLLCVAYLILWERKLIGWMHVRIGPNRVGPLGLLQPIADVLKLLLKEVMMPTQVSRGMYLIAPLMVLMPAVAIWAVIPFQAEVVMADVNAGLLYVMAISSVGVYGVILAGWASNSKYAFIGAMRAAAQMVSYEIAMGFALVTVLMVAGSLNLSAIVNGQNTGYFADMGINILSWNWLPLLPMFGVYFISGVAETNRHPFDVVEGESEIVAGHMIEYSGMGFALFFLAEYINMIIISTMTALMFLGGWAPPFESVVTNAIPGFFWLLIKVFLLLSVFIWIRASFPRYRYDQIMRLGWKVFIPLTVAWLIIVAIWIKSPWNIWH
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.