PharMolix/UniProtQA huggingface dataset:
Protein: HUTH_THEAC
Sequence: MIEIDGRSLRVEDVYAVAVEYDRVSISDDTLKAVEEKHEAFLKLINSGKTVYGVNTGFGSLLNVHIERDQEIELQKNLIRSHSSGVGDYLENRYVRAIMAVRLNSLAAGYSAVSADLLNMMVEMLNRDVIPAVPKYGSVGASGDLAPLAHIGLAMMGEGKAFFEGRLMDSARALEKAGLKPYQFKEKEGVALINGTSFMSGILSIAVMDAHDILENAIRSALLSFEALGGTSKAFTPWILGARPHLGQVAIGNRFREYLTGSDIVKRADSVKVQDAYTLRCIPQVYGSVADVIDYVENVLSVEINSATDNPLFNGEEVVSGGNFHGEPVALAADFLAIALTDLGNMVERRIARLVDTNLSGLPPFLTPDSGLNSGYMIPQYTAAALCNRNKVLAYPSSADTIPTSANQEDHVSMGATGSLKLLEIIDNVRYIIAIEYLLGSQALEFTDKGMSPSTRKIYEKIREKVEKLDHDRPPSFDIETIRKMMDKKEFISALP
What are the official names of this protein?
Probable histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_LACGA
Sequence: MTKKDIRILAFESSCDETSTAVIKNGREIESLIVATQIKSHQRFGGVVPEVASRHHIEVITQITKEALAEANATWDDIDAIAVTYGPGLVGALLIGVSAAKAASMATGIPLIGVDHIMGHIMAAQLKDEIEYPALALQVSGGHTEIVLMKDPIHFEIVGDTRDDAAGEAYDKIGRVLGVNYPAGKTIDEWAHKGKDTFHFPRAMMEDDDYDFSLSGLKSAFINTCHHADQIHEKLDKYDLAASFQASVVDVLSHKTIRAIKEYKPKTFILGGGVAANHGLRDRLAEEIEKLPADIKPKVILPDLKLCGDNAAMIGAAAYNLYKAGKFSDENLNADPSLELPYADSMLK
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LTAS1_BACSU
Sequence: MKKLFSYKLSFFVLAVILFWAKTYLSYKTEFNLGVKGTTQEILLIFNPFSSAVFFLGLALLAKGRKSAIIMLIIDFLMTFVLYANILFYRFFDDFLTFPNIKQSGNVGNMGDGIFSIMAGHDIFYFLDIIILIAVLIWRPELKEYKMKKRFASLVILSGIALFFINLHYAEKDRPQLLTRTFDRNYIVKYLGLYNYTIYDGVQTAQTETQRAYASSDDLTSVENYTTSHYAKPNAEYFGSAKGKNIIKIHLESFQSFLIDYKLNGEEVTPFLNKLAHGGEDVTYFDNFFHQTGQGKTSDAELTMDNSIFGLPEGSAFVTKGENTYQSLPAILDQKEGYTSAVLHGDYKSFWNRDQIYKHIGYDKFFDASTYDMSDENVINMGLKDKPFFTESIPKLESLKQPFYAHLITLTNHYPFNLDEKDASLKKATTGDNTVDSYFQTARYLDEALEQFFKELKEAGLYDNSVIMIYGDHNGISENHNRAMKEILGKEITDYQNAQNQRVPLMIRVPGKKGGVNHTYGGEIDVMPTLLHLEGIDSQKYINFGTDLFSKDHDDTVAFRNGDFVTPKYTSVDNIIYDTKTGEKLKANEETKNLKTRVNQQLSLSDSVLYKDLLRFHKLNDFKAVDPSDYHYGKEKEIK
What is the function of this protein?
Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate, a reaction that presumably uses phosphatidylglycerol (PG) as substrate.
What are the official names of this protein?
Lipoteichoic acid synthase 1.
What is the protein family that this protein belongs to?
Belongs to the LTA synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [Processed glycerol phosphate lipoteichoic acid synthase 1]: Secreted. Note=The secretion into the extracellular medium is dependent on SecA and Ffh.
Protein: FUCP_ECOLI
Sequence: MGNTSIQTQSYRAVDKDAGQSRSYIIPFALLCSLFFLWAVANNLNDILLPQFQQAFTLTNFQAGLIQSAFYFGYFIIPIPAGILMKKLSYKAGIITGLFLYALGAALFWPAAEIMNYTLFLVGLFIIAAGLGCLETAANPFVTVLGPESSGHFRLNLAQTFNSFGAIIAVVFGQSLILSNVPHQSQDVLDKMSPEQLSAYKHSLVLSVQTPYMIIVAIVLLVALLIMLTKFPALQSDNHSDAKQGSFSASLSRLARIRHWRWAVLAQFCYVGAQTACWSYLIRYAVEEIPGMTAGFAANYLTGTMVCFFIGRFTGTWLISRFAPHKVLAAYALIAMALCLISAFAGGHVGLIALTLCSAFMSIQYPTIFSLGIKNLGQDTKYGSSFIVMTIIGGGIVTPVMGFVSDAAGNIPTAELIPALCFAVIFIFARFRSQTATN
What is the function of this protein?
Mediates the uptake of L-fucose across the boundary membrane with the concomitant transport of protons into the cell (symport system) (PubMed:2829831, PubMed:8052131).  Can also transport L-galactose and D-arabinose, but at reduced rates compared with L-fucose.  Is not able to transport L-rhamnose and L-arabinose (PubMed:2829831).  Binds D-arabinose with the highest affinity, followed by L-fucose, and then by L-galactose (PubMed:9826601).
What are the official names of this protein?
L-fucose-proton symporter, 6-deoxy-L-galactose permease, L-fucose permease, L-fucose-H(+) symport protein.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PA12B_VESVE
Sequence: FNPCPYSDDTVKMIILTRENKKHDF
What is the function of this protein?
Catalyzes the hydrolysis of glycerophospholipids such as phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine) and has a moderate activity to hydrolyze lysoglycerophospholipids such as lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine), but is unable to hydrolyze sphingomyelin.  In addition to acting as an allergen, it possesses a potent hemolytic activity on red blood cells of mice (99. 3% of hemolysis at 3. 0 ug/ml).
What are the official names of this protein?
Phospholipase A1 verutoxin-2b, PLA1, VT-2b.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: RSMA_RHIE6
Sequence: MAALDGLPPLRDVIQRHGLDARKALGQNFLLDLNLTQKVARTAGGLEGMTVFEVGPGPGGLTRAILALGAKKVIAVERDARCLPALAEIADHYPGRLEVIEGDALKADFESLAPEGAVKIIANLPYNVGTQLLVNWLLPKAWPPFWQSLTLMFQKEVGERIVATEDDDHYGRLGVLCGWRTEARMAFDVPPQAFTPPPKVTSTVVHLTPRKNPIPCSVANLEKVTQAAFGQRRKMLRQSLKPLGGESLLVKAGIDPARRAETLSVEEFCLLANSL
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_THISH
Sequence: MPLITLPDGSERRFDAPVTVRDVAADIGAGLAKAALAGRVNGRLVDTSHLIEDDASLAIITDRDPEGLEVIRHSTAHLLAQAVKDLFPSAQVTIGPVIDNGFYYDFAFERPFHPDDLEKIEARMKELAKADLPVSRSVMDRDEAVDFFRDQGEEYKAQIIADIPAGETISLYKQGEFIDLCRGPHVPSTGKLKAFKLTKVAGAYWRGDSSNEMLQRIYGTAWPNKQQLDDYLHRLAEAERRDHRRIGTELNLFSIQEDAGGGLVFWHPKGARIRRAIEQFWFDMHERAGYQFLYTPHIANLDLWKTSGHADFYSESMYEPMEDDNQAFQLKPMNCPFHVLVYKDRLHSYRDLPLRWAEMGTVYRREMSGALHGLMRVRGFTQDDAHIFCREDQIEAEILRILDLTLEVLQAFGFDDFDVNLSTRPDKAVGSDQIWEHATAALKAALEKKGLDYSVDEGGGAFYGPKIDIKIRDAIGREWQCSTVQLDFNLPERFEMEYVAEDNSRRRPIMIHRALLGSVERFFGVLIEHYAGSFPLWLAPVQVQVLTITDRQDDYAREVADRLRNRGIRADADLRNEKIGFKIREHTLQRVPYLLVLGDREMETNTVAVRTRSGEDLGSMDLNQLSERLAGEIASRGRSHLED
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_STRPC
Sequence: MTDNSKIRVVVGMSGGVDSSVTALLLKEQGYDVIGVFMKNWDDTDEFGVCTATEDYKDVAAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVMCNKEIKFKAFLDYAMTLGADYVATGHYAQVKRDENGTVHMLRGADNGKDQTYFLSQLSQEQLQKTLFPLGHLQKSEVREIAERAGLATAKKKDSTGICFIGEKNFKQFLSQYLPAQKGRMMTIDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNQPWFVVGKDLSQNILYVGQGFYHEALMSNSLDASVIHFTREMPEEFTFECTAKFRYRQPDSHVTVHVRGDKAEVVFAEPQRAITPGQAVVFYDGKECLGGGMIDMAYKNGQPCQYI
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LRAD3_XENTR
Sequence: MWLLYLILGSVESQLLPGNNHTTECNIPGNFMCSNGRCIPGGWQCDGNPDCFDESDEKECPRARSRCGPNFFPCTSGIHCIIARFQCNGFEDCPDGSDEENCTAHPLLCSNSRFHCKNHLCIDKSFVCDGQNNCLDNSDEEHCHSPQEPGSEQDYVSSENQLLYYPSITYTIIGSSVIFVLVVALLALVLHHQRKRNLMSLPVHRLQHPLLLSRLVVLDHPHHCRVTYNVNNGIQYMSGQGYQQPVSVESPPSYTEAVLDHSSRPPWFDLPPPPYPSDMESVSQTELPPYRSRTGSSASAGSTEHPRGTPCGTESPTEPQDPTAAPSDDLPSTEVDV
What are the official names of this protein?
Low-density lipoprotein receptor class A domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the LDLR family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: SAD2_ARATH
Sequence: MDLHSLALILRTAALSPIPDERKVSEQQLNQLEHTPQHLVRLLQIAVDGNCDMAVRQIASIQFKNLIAKNWSPEDCGPAVRQQQIFESDKELVRDNILVYVTQVPTLLRSQLGESLKTIIYADYPEQWPRLLDWVKYNLQNQQIYGALFVLRILSRKYEFKSDEERTPVSRIVEETFPQLLTIFNGLIQIPNPSLEIAELMKLICKIFWSSIYLELPRQLFDLNVFNAWMVLFLSVSERPVPVEGQPMDPELRKSWGWWKVKKWTVHILNRLYSRFGDPKLQSPENKPFAQMFQKNYAGRILEGHLNFLNTIRVGGYLPDRVINLLLQYLSNSISKNSMYKLLLPRLDVLLFEIVFPLMCFNDNDQKLWEEDPHEYVRKGYNIIEDLYSPRTASMDFVNELVRKRGKENLPKFVKFVVEIFLSYEKATVEEKPYRQKDGAMLAVGALCDKLKQTDPYKSQLELMLVQHIFPDFNSPVGHLRAKAAWVAGQYAHINFSDQNNFRKALHSVVSGLRDPDLPVRVDSVFALRSFVEACKDLNEIRPILPQLLDEFFKLMNEVENEDLVFTLETIVDKFGEEMAPFAFGLCQNLAAAFWRCLNTSEANDDSDDMGALAAVGCLRAISTILESVSSLPQLFVEIEPTILPIMQKMLTTDGQEVFEEVLEIASYMTFYSPSISLDIWSLWPLMVEALVDWGIDFFPNILVPMDNFISRGTAHFLTCKEPDYQQSLYNVLSTLMTDRNIEDSEIESAPKLIEVVFQNCKGQVDQWVEPYLRLTVDRLQRAETSYVKSLLIQVVANMLYYNPGLTLGVLHNTGLASKVFDLWFQMLQQKRKSGLPANFKREHDKKVCCLGLTSLLALPGGQFPDEALQRVFRATLDLLVAYKNQLAEAAKETEVDYEEEMNGLQSSDDDYDDDGSDGEMDDTEEGDEAQSVKLQKLAAQAKAFHYDDDDDDDSDDDFSDEDEFQSPIDEVDAFVFFVDAIRVMQASDAQRFQNLNQSLDFTYQAIANGIAQHAELRRVEIEKEKQKKLAAASTPVTAL
What is the function of this protein?
Functions probably in nuclear protein import, either by acting as autonomous nuclear transport receptor or as an adapter-like protein in association with other importin subunits (Probable).  Involved in the regulation of the abscisic acid (ABA)-mediated pathway in response to cold or salt stress (PubMed:16889648).  Involved in UV-B responses by regulating accumulation of UV-absorbing pigments through mediation of MYB4 nuclear transport (PubMed:17993626).  Involved in trichome initiation by controlling GL1, GL2, GL3 and TTG1 transcription and may affect an upstream regulator of GL3 and disrupt complex function (PubMed:18713401, PubMed:19234066).  Acts as negative regulator miRNA activity by regulating miRNA loading into AGO1 complexes (PubMed:21984696).
What are the official names of this protein?
Importin beta-like SAD2, Protein ENHANCED MIRNA ACTIVITY 1, Protein SUPER SENSITIVE TO ABA AND DROUGHT 2, Protein UNARMED 9.
What is the protein family that this protein belongs to?
Belongs to the importin beta family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NDE1_USTMA
Sequence: MSEHGADLRFDSPEKEIKHWKSKVADMQDALRETESSLQDFVESSKELEQEMEKELSASNKTISDLKRRNEQLSGDLEDWKSKYSRALSEHNATLTTLQKELGQLRESVDIYKAKLRDTELTNDELENAERMVASSLADMEGKYNKTIEKTALLEEELIEKTRLDEENQRLKDELREMTEEMTILRDLVTRSRAISRADTMASSTYDDSTAPRSEQSFDSSPIKPSSAARATERPSSRQALSSPVTNRVPISRRLGAMGHNRRLSRDVRAAEAPSLAAVLDDSPTATTTSAAPTRSSTLSRRDPLAATPYHHGASTSHGLTSSPSARAQLRASVRAAARIGGAVSVSSAPRSTNLSANGGAAGSKRMMAEMISKMKALESRINSAKDLSRVVGPGDESAIPRPSSRMATIGSPSANGHNSIHMPTSTPRAPRASMDGNRTIGSSIPVPSRVRRPSSRMSERGTPPMPSLGLPRAQTPSSLHARGSSRADGPSPLPLHEFMDHDPASTLPHAARYAAAQASVAKRRTSMSGSGMSHSASHGSLAKVRSGSTLPRSTTPSTVAAPRVTQSSMTYYGAEASMSKRTPLSTRLASSHRNASSARGSINGPPSSWKTSAMPAQTLSRSRSSSLGSETETF
What is the function of this protein?
Required for nuclear migration.
What are the official names of this protein?
Nuclear distribution protein nudE homolog 1.
What is the protein family that this protein belongs to?
Belongs to the nudE family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Localizes to the plus ends of microtubules.
Protein: HEMTM_RIFPA
Sequence: MSFEVPSPYVWDDSFRVAYDNLDSEHQALFKCIAKCAENRADAAALADLVKVTVDHFADEERMMAKTNFSGLPEHNKIHSEFVAKIKSLSAPLDDATVAFAKQWLVNHIKGIDFKYKGNL
What is the function of this protein?
Myohemerythrin is an oxygen-binding protein found in the retractor muscles of certain worms.  The oxygen-binding site contains two iron atoms (By similarity).
What are the official names of this protein?
Myohemerythrin, MHr.
What is the protein family that this protein belongs to?
Belongs to the hemerythrin family.
Protein: GAS1_MAGO7
Sequence: MSLKSLIAATILAAPLVAGHGAIIKAVGDAGGEGMGLGVVTSTPRDGTRRDPFQQDSTRFKGQQADTFGETVGGGQNDVESMTKAIMAETGSQLPQISPGGSLQMTLHQVNGDGAGPYTCELNDDASGAQWQQIRVTTTPPGRNSRNRDGAMTDFPLVAEIPQRQACTGTVAGQTNVCLVRCMNAARAGPFGGVVAAQLAGSQTPQAARRALAESVKRSELIVSGLKKRGYNIADLSQEEIDELRRDGEIA
What is the function of this protein?
Appressoria-specific virulence factor required for appressorial penetration in host and lesion development.
What are the official names of this protein?
Appressoria-specific virulence factor GAS1.
What are the subcellular locations of this protein?
Cytoplasm. Note=Exclusively located in the cytoplasm of appressoria cells.
Protein: PANT_LACLM
Sequence: MKKSKASDVAILAIFIAIMVVVQLFTQFVINVWPFPVKPTLLHLPVIIGSIILGWRKGAFLGLVWGLISFVTATIVTTPTSFLFSPFQPVIGTHHGSPWGLFIAFIPRILVGILPYFVYKIANNRLGAGLAAFAGTATNTVLVLTSIFLFFGSTLKWSLSYLLGAIVATNSLTEVIIAVILTTAIVPALTKARNNS
What is the function of this protein?
Probably a pantothenic acid-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.  The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins.
What are the official names of this protein?
Pantothenic acid transporter PanT, Pantothenic acid ECF transporter S component PanT.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ST1A4_HUMAN
Sequence: MELIQDTSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLINTYPKSGTTWVSQILDMIYQGGDLEKCNRAPIYVRVPFLEVNDPGEPSGLETLKDTPPPRLIKSHLPLALLPQTLLDQKVKVVYVARNPKDVAVSYYHFHRMEKAHPEPGTWDSFLEKFMAGEVSYGSWYQHVQEWWELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETMDFMVQHTSFKEMKKNPMTNYTTVPQELMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL
What is the function of this protein?
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic monoamines (neurotransmitters such as dopamine, norepinephrine and serotonin) and phenolic and catechol drugs.
What are the official names of this protein?
Sulfotransferase 1A4, ST1A4, Aryl sulfotransferase 1A3/1A4, Sulfotransferase 1A3/1A4.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBS7_SCHPO
Sequence: MSETSSNSPASGSKEAVPKSLAGSTSNIPNELFVGPDGRPLSQNAQGASKSSSKVVPQALVPEDDIRAVEGILNYGGSNDNRPVSHTHTFVELQKSHQNHLTENDRNFGTSRLDDVAPNADGVRRLRTSGSSTGLSNAPPSANVSKASSNLSLASLAKTQPERATPEVCVPLNPDTGSVPLIHPEQTDRGLPYAPDEKFHNSGSLKLPKGASLEDLSRSPSRAVLNEDGNVDECAPPEPWENEYNEVLDDVENAVVGTSPLEYTSKPLAANRQRSTADLTESDNICGLTAGKSDPVTDVDESQTIDEQSIPEAEKGFYTKDGEGTAGLPFDIVSNLDIPNENAHESSRSKKKHTGPSLSSASQPSAASSSSSSEPSNLDKINDVKKNIEVSANEPQPRPVKEDVPKSQVGGETDTTDVINNSTPKEETEESPSTELPETGKEQPPNKAEPAVPTEASSTKPSEAAEESTPRFSVRPNKFTGSRAGFVAALESRLQKGPLMRSFVPNKSKSPSGTKSPASGETSEAGVKETETTTSSESALPDARKSRARGPVRRPPTSVNTKPSFSVSGIDVFLNLPQSSVMKKKGVETRKEVEPKEEAVIPEEDVEVEVETEEQ
What are the official names of this protein?
Uncharacterized serine-rich protein C18E5.07.
Protein: PUR5_SHISS
Sequence: MTDKTSLSYKDAGVDIDAGNALVGRIKGVVKKTRRPEVMGGLGGFGALCALPQKYREPVLVSGTDGVGTKLRLAMDLKRHDTIGIDLVAMCVNDLVVQGAEPLFFLDYYATGKLDVDTASAVISGIAEGCLQSGCSLVGGETAEMPGMYHGEDYDVAGFCVGVVEKSEIIDGSKVSDGDVLIALGSSGPHSNGYSLVRKILEVSGCDPQTTELDGKPLADHLLAPTRIYVKSVLELIEKVDVHAIAHLTGGGFWENIPRVLPDNTQAVIDESSWQWPEVFNWLQTAGNVERHEMYRTFNCGVGMIIALPAPEVDKALALLNANGENAWKIGIIKASDSEQRVVIE
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_PARUW
Sequence: MQQEERGSRKVKKGIVVSNKMQKTVVVKVERTFAHPQYGKIVTRGKKYYAHNESGDLQIGDEVKIMETRPLSKLKRWRVVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: QUEA_BACC3
Sequence: MDINLFDFHLPEELIAQVPLEERETSRLMVLDRETGDIEHKHFTDILSYLHEGDCLVLNETKVMPARLHGVKEDTGAHIEVLLLKQEEGDKWETLVKPAKRVKEGTVISFGEGKLKATCTGTADQGGRQLEFSYDGIFYEILDELGEMPLPPYIKETLEDRDRYQTVYAKEIGSAAAPTAGLHFTEELLEKLKQKGVELAFITLHVGLGTFRPVSADTIEEHHMHAEYYHMSEETAALLNRVKENGGRIITVGTTSTRTLETIATDHNGKLCAASGWTDIFMYPGYEFKAIDGLITNFHLPKSTLIMLVSAFANRDNVLHAYNEAVKEKYRFFSFGDAMFIASHAKMGNK
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_STRCO
Sequence: MIAFVSGTVAALAPDAAVIEVGGVGMAVQCTPNTLSTLRLGKPAKLATSLVVREDSLTLYGFADDDERQVFELLQTASGVGPRLAQAMLAVHQPDALRRAVATGDEKALTAVPGIGKKGAQKLLLELKDRLGEPIGAPAVGAPVSTGWRDQLHAALIGLGYATREADEAVSAVAPQAEAAGGTPQVGALLKAALQTLNRAR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: QUEC_BRUA2
Sequence: MKTLVICSGGLDSVSLAHKMAAEHELTGLLSFDYGQRHKKELDFAQACAKRLGVPHQIIDIRTIGASLTGSALTDDVDVPDGHYAEETMKVTVVPNRNAIMLAIAFGVAAAQKADAVALAVHGGDHFIYPDCRPGFIEAFQTMQKHALDGYADVKLLAPYVHATKADIVADGAKYRTPFEATWSCYKGADRHCGRCGTCVERREAFHLAGIDDPTSYEDADFWRATTQKRNA
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: LEUC_PHOPR
Sequence: MSAKTGTSKTLYEKVYDAHVAVAAEGENPILYIDRHLVHEVTSPQAFDGLREKGRKVRQIGKTFATMDHNVSTQTKDINASGEMARIQMETLAKNCKEFGVTLYDLNHKYQGIVHVIGPELGITLPGMTIVCGDSHTATHGAFGSLAFGIGTSEVEHVLATQTLKQSLAKTMKIEVVGKVAEGITAKDIVLAIIGKTTAAGGTGYVVEFCGEAITDLTMEGRMTVCNMAIELGAKAGLIAPDQTTYDYIKDRKFSPTGANFDAAVEYWSTLKTDDGATFDAVVTLDAKNIKPQVTWGTNPGQVIAIDELIPGPDNFSEQVDKTSAEKALAYMGLEAGKKLSDFDIDKVFIGSCTNSRIEDMRAAAAIAKGRKVAANVQALVVPGSEQVKAQAEKEGLDKIFIEAGFEWRLPGCSMCLAMNNDRLGPKERCASTSNRNFEGRQGRDGRTHLVSPAMAAAAACAGHFVDIRDLDNATA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: Y4063_MYCPA
Sequence: MADSSFDIVSKVDRQEVDNALNQAAKELATRFDFRGTDTTIAWKGDEAIELTSSTGERVKAAVDVFKEKLIRRDISMKAFDAGEPQASGKTYKVNGTLKQGISSESAKKITKLIRDEGPKGVKTQIQGDEIRVSSKKRDDLQAVIAMLKQADLDVALQFVNYR
What are the official names of this protein?
UPF0234 protein MAP_4063c.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: OYE2_YEAST
Sequence: MPFVKDFKPQALGDTNLFKPIKIGNNELLHRAVIPPLTRMRAQHPGNIPNRDWAVEYYAQRAQRPGTLIITEGTFPSPQSGGYDNAPGIWSEEQIKEWTKIFKAIHENKSFAWVQLWVLGWAAFPDTLARDGLRYDSASDNVYMNAEQEEKAKKANNPQHSITKDEIKQYVKEYVQAAKNSIAAGADGVEIHSANGYLLNQFLDPHSNNRTDEYGGSIENRARFTLEVVDAVVDAIGPEKVGLRLSPYGVFNSMSGGAETGIVAQYAYVLGELERRAKAGKRLAFVHLVEPRVTNPFLTEGEGEYNGGSNKFAYSIWKGPIIRAGNFALHPEVVREEVKDPRTLIGYGRFFISNPDLVDRLEKGLPLNKYDRDTFYKMSAEGYIDYPTYEEALKLGWDKN
What is the function of this protein?
Flavin-dependent enoate reductase that catalyzes the chemo- and stereoslective hydrogenation of electron-poor alkenes.  The enzyme is reduced by NADPH, and oxygen, quinones, and alpha,beta-unsaturated aldehydes and ketones can act as electron acceptors to complete catalytic turnover.  The physiological oxidant remains elusive (By similarity).  Has an antioxidant activity, reducing reactive oxygen species (ROS) levels when overexpressed.  Formation of OYE2-OYE3 heterodimers contribute to the induction of programmed cell death upon oxidative stress (PubMed:17897954).
What are the official names of this protein?
NADPH dehydrogenase 2, Old yellow enzyme 2.
What is the protein family that this protein belongs to?
Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion.
Protein: ISPF_PSEPW
Sequence: MRIGHGYDVHRFCDGDFITLGGVRIPHKYGLLAHSDGDVLLHALSDALLGAAGLGDIGKHFPDTDPQFKGADSRVLLRHVVGIVQAKGWKVGNVDATIVAQAPKMSPHIETMRQRIAEDLQVELDQVNVKATTTEKLGFTGREEGIAVHAVALLLPA
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: GL_EHV2
Sequence: MRSLDRYAIFILLACGLLWRPCLSSVPMPCCPIDSKKDVSGLPSVFEVKEIFFNYPQTCNYTNVAQFTYVPQGANVSTVVCANGFNLMSFILAVLQRVFEKPHNMGLLAENINKIRTDYALNFTAVNSESSRFNVVPVGRNGKVVTTTRVVKRSARSGSGAPPG
What is the function of this protein?
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell.  Acts as a functional inhibitor of gH and maintains gH in an inhibited form.  Upon binding to host integrins, gL dissociates from gH leading to activation of the viral fusion glycoproteins gB and gH.
What are the official names of this protein?
Envelope glycoprotein L, gL.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein L family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Extracellular side. Host cell membrane; Peripheral membrane protein; Extracellular side. Host Golgi apparatus, host trans- Golgi network. Note=gL associates with the extravirion surface through its binding to gH. During virion morphogenesis, this protein probably accumulates in the host trans- Golgi where secondary envelopment occurs.