PharMolix/UniProtQA huggingface dataset:
Protein: TRE12_DROME
Sequence: MKILMRADTHVSFSVPADGLKANFTFSQVLAALSVSLCSLVVGFVSAYTSPALVSMTDRTITSFEVTKDAGSWVGGIMPLAALAGGITGGPLIEYLGRRSTILATAVPFIVSSLLIACAVNVIMILCGRFLTGFCVGIASLSLPVYLGETLQPEVRGTLGLLPTALGNIGILVCYVAGSFMNWSMLAFLGAALPVPFLILMIIIPETPRWFVNRGQEERARKALKWLRGKEADVEPELKELMQSQADADRQATQNTCLELFKRNNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDSNLSTIIVGVVNFFATFMGIILIDRLGRKILLYVSDIAMIVTLSILGGFFYCKAHGPDVSHLGWLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGPAASVVTAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICIVGLFFVIIFVPETRGKSLEEIERKMMGRVPMSSVVNIKPFPFNM
What is the function of this protein?
Fails to transport trehalose.
What are the official names of this protein?
Facilitated trehalose transporter Tret1-2 homolog, DmTret1-2.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Trehalose transporter subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYE_PROM1
Sequence: MKVRVRLAPSPTGTLHLGTARTALFNWLFAKKEGGTFLLRIEDTDIERSREEYINDIYDGLKWLGINWDESPTIQSERVNEHKQIIKTLVDKGFAYKCYASEAELDEMRETQKRNGLAPKYDNRHRNLTPEQESEFIKLGRDPVIRFKISDEKLISWNDLIRGKMTWSGKDLGGDMVIARRAPGNSIGDPLYNLVVVADDSAMKISHVIRGEDHLANTAKQILLYEALDLNIPVFAHTPLILNSEGKKLSKRDGVTSISEFKKMGYTSEAMANYMTLLGWSVPEGINERFNISEVSEIFSFKKVNKASAKFDWDKLNWLNSQVIHEMSAETLLENLEPLFKENGWHLPSHEWGINLVGLIGPSMVLINDGVDQAKPFFEEQELSDDGKKQLEIKEAAVILKFILEKLADSDAASFSKEKALDLIDQATKSCKVKKGVVMKSLRAALFGTLNGPDLIQSWVLLSRFSKDRARISRLI
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_SHEAM
Sequence: MRHRKSGRQLNRNSSHRQAMFRNMASSLVRHEIIKTTAVKAKELRRVVEPLITLAKSDSVANRRLAFARTRDQEVVGKLFNELGPRYQERPGGYTRILKCGLRAGDKAPMAYIELVGRPEAAQAVEVEAAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: SFAS_SPESI
Sequence: PTPSPEARVASRPFLDSPLPGSPRSGSPTGYITATKAISAGKLEHVAEKFSNFYNEIELEKQQRRMADAARFQMLTDSIAKLEKSLEAEIKRRAESDKQIQVHFESEVKGLQERTALQLADLQAAFKTSVDGLSRTMQDLHTIIKEEREQRRSDIEHLAGSLVNKVNECVAALDEERISRMDAESKILKQIATDVFRVQEKIDTEKGTREAELATLRSEIHEVLGNRNLSDEKFQTLVLDEINNLKSAVQMEREERISEDDEIVQAVNDYTRALQDGLRIVNNS
What is the function of this protein?
Major component of the striated microtubule-associated fibers (SMAFs; system-I-fibers).
What are the official names of this protein?
SF-assemblin.
What is the protein family that this protein belongs to?
Belongs to the SF-assemblin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: GOG8T_HUMAN
Sequence: MAEETQHNKLAAAKKKLKEYWQKNSPRVPAGANRNRKTNGSIPEKATSGGCQPPRDSATGFHREGPTSSATLKDLESPCQERAVVLDSRSVEISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKEELNTDLYHMKRSLRYFEEKSKDLAVRLQHSLQRKGELESVLSNVMATQKKKANQLSSRSKARTEWKLEQSMREETLLKVQLTQLKESFQQVQLERDEYSEHLKGERARWQQRMRKMSQEICTLKKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQAQVKKNQRISLLNQRQEERIQEQEERLRKQEERIQEQHKSLQQLAKPQSVFEEPNNENKNALQLEQQVKELQEKLGEEHLEAASQQNQQLTAQLSLMALPGEGHGGEHLDSEGEEAPQPMPSVPEDLESREAMSSFMDHLKEKADLSELVKKELCFIHHWRDRRHQKTHHLLSEPGGCAKDAALGGGHHQAGAQGGDEGEAAGAAADGIAAYSNYNNGHRKFLAAAHNPADEPGPGAPAPQELGAADKHGDLREVSLTSSAQGEAREDPLLDKPTAQPIVQDHQEHPGLGSNCCVPFLCWAWLPRRRR
What are the official names of this protein?
Golgin subfamily A member 8T.
What is the protein family that this protein belongs to?
Belongs to the GOLGA8 family.
Protein: MURB_HELHP
Sequence: MQTHIINFAKYSSIKIGAPLEVSLIQTPQDAISALSQNMRIIGKANNLLVSPAAQKLAMLDKHFAYLKDCGNYIEIGGAYSSGRIFSYFKSHNLAGAEFLQALPGSLGGLVKMNAGMKSYEIKQLLQAINVNGKWQDRESFPMNYRDSGIEGVILAARFHKREGFNNALQADFIALRKNHPKEPSCGSCFKNPKGDFAGRLLESVGLKGYCIGDAAFSEKHANFLINKGKATFEDALSLITLAKKRVFEASGIDLECEVQILQ
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASSY_BURTA
Sequence: MTTILENLPAGQKVGIAFSGGLDTSAALHWMRIKGAVPYAYTANLGQPDEDDYDAIPKRAIQYGAEGARLIDCRAQLVAEGIAALQCGAFHISTAGVTYFNTTPIGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLVNPDLKIYKPWLDQQFIDELGGRAEMSEFMRQAGFEYKMSAEKAYSTDSNLLGATHEAKDLESLESGIKIVNPIMGVAFWRDDVKIDKEAVTVRFEEGRPVALNGVEYKDAVELLLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGLALLYIAYERLVTGIHNEDTIEQYRENGRRLGRLLYQGRWFDPQAIMLRETAQRWVARAVTGEVTVELRRGNDYSILATRSPNLTYQPERLSMEKVQSTFSPRDRIGQLTMRNLDITDTRDKLRIYSEVGLLTPGESSALPKLKEDESGN
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INT13_DROYA
Sequence: MFERNQKTIFVLDHTRYFSIASEEYISMDFLKGKPSADGGATGAAGNASGGGGSQFSKSLWTCACESSIEYCRVVWDLFPGKKHVRFIVSDTAAHIVNTWSPSTQNMSHVMNAMVMVGVPSRNVPTSSDYSVIHGLRAAIEALAEPTDEQLAAMADLGTDELPRIPNKGRVICITSARDNTSMKSLEDIFNTVLVQQNALAAPPAKKGLVIDHCHLVILNIVPLGVESLVTNRSLLKISPLLDVEIHTVSAPDISYKLTHLILNHYDLASTTVTNIPMKEEQNANSSANYDVEILHSRRAHSITCGPDFSLPTSIKQGATYETVTLKWCTPRGCGSADLQPCLGQFLVTPVDVTSRPSSCLINFLLNGRSVLLEMPRKTGSKATSHMLSARGGEIFVHSLCITRSCMDEAPSITDGPGGRVSDYRTAELGQLIKMSRMLPLKVKDPSAPPLTRRLPRYFPLTTSSSILFHLQRHISWLPHFLHLLVKEDMDKQDEVRCQQHIHELYKSASRGDVLPFTHTNGARLKLSKAKDQYRLLYRELEQLIQLNATTMHHKNLLESLQSLRAAYGDAPLKSEPGASLLRSYTESPLSPERLEPNSSGSASGSSNSNSLLKASKRRMSSCGQRSLLDIISSAERSQSNKRLDFSGRLCTPLGQVAKLYPDFGNKDKDTVASGASITPNVKEESVRS
What is the function of this protein?
Plays a role as a regulator of spermatogenesis.  Crucial regulator of the mitotic cell cycle and development.  Required for the correct dynein-dynactin perinuclear localization important for nucleus-centrosome coupling that occur upon meiotic progression of primary spermatocytes.  Crucial regulator of the mitotic cell cycle and development.  Plays a role in sperm motility and fertility.  May have a role in the PNG/PLU/GNU pathway (By similarity).
What are the official names of this protein?
Protein asunder, Cell cycle regulator Mat89Bb, Maternal transcript 89Bb, Set apart in position or space protein.
What is the protein family that this protein belongs to?
Belongs to the asunder family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, perinuclear region. Note=Colocalizes with dynein-dynactin on the nuclear surface at the meiotic G2/prophase transition in primary spermatocytes. Nuclear location is required for recruitment of dynein motors to nuclear envelope at G2/M.
Protein: NCAP_DHVI1
Sequence: MSSTTPKRSEPADEDMEVEVKRSKVETDPKSTQRKYEDFKAQMVTLANQLKIDLKVKHNADIIGSIVMAACTGNAIRETGKYSFFFNDEKDGWKLREVELNCKPVIDWANQTLTDEQKREWYPFLASLQLCVKTEDAILWQRNPVTRELQVSPVCEPFATGYNIKDKLKKSRPLSVGPLNHLLHWVNLQTEKSVGKGRKLSPRAAAGIRKRLEATLMRQTIGQSQKAMLRQIFDGKLAYVRTLAHSYCSIKPHIENQFVLPYSVIAVTDSFENADMSSEWVYKKLCEASKKILLTGPNESWKTFMAQMLIYCTFRCLHEDLGVLTSMFGMVFEPRKSKGKYCKSSELQVLGSQEITYKFWSKPQRGAPRNLGGARRGQICTRPSFRGVRATYNQYSSLEQLEKACGNPTSENVVEALNAEFEDTQNSPLKAQGRSTKGGLPMSTKATSRLQASFCLKFSLICVCNFCCFLSLLLGIC
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion.
Protein: FOLD_SALSV
Sequence: MAAKIIDGKTIAQQVRSEVAQKVQARVAAGLRAPGLAVVLVGSNPASQIYVASKRKACDEVGFVSRSYDLPETTSEAELLALIDTLNADNTIDGILVQLPLPAGIDNVKVLERIAPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTYGLNAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKDLRHHVEHADLLIVAVGKPGFIPGEWIKEGAIVIDVGINRLENGKVVGDVVFDEAAARASYITPVPGGVGPMTVATLIENTLQACIEYHDPQGK
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: CAMT_POPTM
Sequence: MATNGEEQQSQAGRHQEVGHKSLLQSDALYQYILETSVYPREPECMKELREVTAKHPWNIMTTSADEGQFLNMLLKLVNAKNTMEIGVYTGYSLLATALAIPEDGKILAMDINRENYELGLPVIQKAGVAHKIDFKEGPALPVLDQMIEDGKYHGSFDFIFVDADKDNYINYHKRLIELVKVGGLIGYDNTLWNGSVVAPPDAPMRKYVRYYRDFVLELNKALAADPRIEICMLPVGDGITLCRRIQ
What is the function of this protein?
Methylates caffeoyl-CoA to feruloyl-CoA and 5-hydroxyferuloyl-CoA to sinapoyl-CoA.  Plays a role in the synthesis of feruloylated polysaccharides.  Involved in the reinforcement of the plant cell wall.  Also involved in the responding to wounding or pathogen challenge by the increased formation of cell wall-bound ferulic acid polymers.
What are the official names of this protein?
Caffeoyl-CoA O-methyltransferase, Trans-caffeoyl-CoA 3-O-methyltransferase, CCoAMT, CCoAOMT.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. CCoAMT subfamily.
Protein: 5MP1_DANRE
Sequence: MNTGKQQKPVLTGQRFKTRKRDEKEKFEPTVFRDTIVQGLNEAGGDLDALAKFLDVTGSRLDYRRYADTLFDILIAGSMLAPGGTRIDDADKTKVTQHCVFNAEENHTTIRSYAQVFNKLIRRYKYLEKAFEEEIKKLLLFLKGFTESEQTKLAMLTGVLLANGTLPPPILTSLFSDNLVKEGISASFAVKMFKAWIAEKDANAVTSALRKANLDKKLLELFPANKQNVEHFTKFFTEAGLKELSDFLRTQQTLGTRKELQKELQERLSQQCPIREIVVYVKEEMKKNDLQEQAVIGLLWTCLMNAVEWNKKEELVTEQALKHLKHYAPLLAVFSTQGQSELVLLLKIQEYCYDNIHFMKSFSKIVVLFYKADVVSEEAIMKWYKDAHAAKGKSVFLEQMKKFVEWLQNAEEESESEGEED
What is the function of this protein?
Translation initiation regulator which may repress non-AUG initiated translation and repeat-associated non-AUG (RAN) initiated translation by acting as a competitive inhibitor of eukaryotic translation initiation factor 5 (EIF5) function.
What are the official names of this protein?
eIF5-mimic protein 1, Basic leucine zipper and W2 domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the BZW family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TARI_STRPS
Sequence: MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEPSIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPLTPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPNRAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEIWTDACKIFVIKGKDVALAKGEYSNLKITTVTDLKIAKSMIEKD
What is the function of this protein?
Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate.
What are the official names of this protein?
Ribitol-5-phosphate cytidylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. TarI subfamily.
Protein: PRX9_PENRW
Sequence: MDASKLPLGSFVGTTLLLFILYKLVKLAYYVGQAKNTGLPYTIVPVLETEFLGKLLTPLIRPLFTSRLSRGKGWPRWIRFSILDWAWEEKRRVHEELGDVFLVVSSEGLICYTADADMSWDVMNRRNEFLKPRDKYKVLEPYGPNVATTEGKAYNFHVRITAPPFNDGSGANDLVWNEASDQARALMESWSQENTTRDLSLDINRLTLAVIAYTGFGKRLDFKTEVSDLRNKIPPGYKMSLHHALHLVTTFMVKILLIPKWIMKMTSMKEIAVAHGELEKYMREMIRTETANLSKDSEYQSADAKGNLLTSVLRASAFEAKAAGRKQAFSEDEVLGNLFLYLLAGYETTANAMTYGFITLALRQDLQDRIIQEVDGVYAEAAAEGRTSLNYTDDFEKFQYTYGFMYEVFRLYPGVCIITKMVPKDTTITVYPENNSPQQHVLPAECRVYLNVNAVHYHERYWPDPWALKPDRWMGTIGATPNARSNKKVVAGDKSRQVRGTLMTFSGGARACLGRKFTQSEYISALATVLREYRIVLGEGMDAKVVKQEIDHLAAGTVTLAPLKYVKLALKKRTDVKTG
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of PR-toxin, a bicyclic sesquiterpene belonging to the eremophilane class and acting as a mycotoxin (PubMed:24239699).  The first step of the pathway is catalyzed by the aristolochene synthase which performs the cyclization of trans,trans-farnesyl diphosphate (FPP) to the bicyclic sesquiterpene aristolochene (PubMed:24239699).  Following the formation of aristolochene, the non-oxygenated aristolochene is converted to the trioxygenated intermediate eremofortin B, via 7-epi-neopetasone (PubMed:24239699).  This conversion appears to involve three enzymes, a hydroxysterol oxidase-like enzyme, the quinone-oxidase prx3 that forms the quinone-type-structure in the bicyclic nucleus of aristolochene with the C8-oxo group and the C-3 hydroxyl group, and the P450 monooxygenase prx9 that introduces the epoxide at the double bond between carbons 1 and 2 (PubMed:24239699) (By similarity).  No monoxy or dioxy-intermediates have been reported to be released to the broth, so these three early oxidative reactions may be coupled together (PubMed:24239699).  Eremofortin B is further oxidized by another P450 monooxygenase, that introduces a second epoxide between carbons 7 and 11 prior to acetylation to eremofortin A by the acetyltransferase prx11 (By similarity).  The second epoxidation may be performed by a second P450 monooxygenase (PubMed:24239699).  After the acetylation step, eremofortin A is converted to eremofortin C and then to PR-toxin (PubMed:24239699).  First the conversion of eremofortin A to eremofortin C proceeds by oxidation of the side chain of the molecule at C-12 and is catalyzed by the short-chain oxidoreductase prx1 (PubMed:24239699).  The cytochrome P450 monooxygenase prx8 also plays a role in this step (By similarity).  The primary alcohol formed at C-12 is finally oxidized by the short-chain alcohol dehydrogenase prx4 that forms PR-toxin (PubMed:24239699).
What are the official names of this protein?
Cytochrome P450 monooxygenase prx9, PR-toxin biosynthesis cluster protein 9.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: HEMH_SALTI
Sequence: MRQTKTGILLANLGTPDAPTPEAVKRYLKQFLSDRRVVDTPRLLWWPLLRGVILPLRSPRVAKLYQSIWMDGGSPLMVYSREQQQALAARLPDTPVALGMSYGSPSLESAVDELLASDVDHIVVLPLYPQYSCSTVGAVWDELGRILARKRRIPGISFIRDYADDGAYIDALAKSARESFARHGEPDLLLLSYHGIPQRYADEGDDYPQRCRDTTRELVSALGLPPEKVMMTFQSRFGREPWLTPYTDETLKMLGEKGTGHIQVMCPGFAADCLETLEEIAEQNREIFLEAGGKKYAYIQALNATPEHIDMILKLTAPYR
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PFKA2_THET8
Sequence: MKRIGVLTSGGDSPGMNAAIRAVVR
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase 2, ATP-PFK 2, Phosphofructokinase 2, Phosphohexokinase 2.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA2AA_CROHD
Sequence: SLVQFEMMIMEVAKRSGLLWYSA
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that shows high lipolytic (1048 umol/mg/min) and weak ADP-induced platelet aggregation activities.  Also shows weak anticoagulant activity (IC(50) is less than 1. 0 uM).  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Acidic phospholipase CHA-E6a, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS4_ZYMMO
Sequence: MSKRHSSKYKIDRRMGENIWGRPKSPVNRREYGPGQHGQRRRSKISDYGLQLKAKQKLKGYYGDVTEKQFRRSYDDASKLKGDTSQNLIGILERRLDMIVYRAKFAPTIFAARQLVSHGHIRVNGVKCNIASRRVNPGDEISLGSKAQEMALVLEAQSLAERDIPDYVLPDGNTKVTFVRIPTLDEVPYPVKMEPNLVVEFYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: ILVC_HELMI
Sequence: MKMYYDADADLSLLEGKIVAVIGYGSQGHAQAQNLKDSGVNVIIGLRPDSNRVKEAQAYGFEVYSVAEAAAKADIIQILIPDEKQGKVYREEIAPYLTEGKALCFSHGFNIHFGQIQPPKNVDVFMVAPKSPGHMVRRMYTMGAGVPTLIAVYQDATGRAKDLALAYAKGTGGTRAGVIETTFREETETDLFGEQAVLCGGASALVKAGFETLVEAGYAPEMAYFECLHELKLIVDLMYEGGISWMRYSISDTAQWGDMNIGPRIITEETKKEMKKVLREIQEGTFAKEWLLENEVNRPKFNALAKADENHEIEIVGKKLRAMMPWLKTAK
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: PP2A_TOBAC
Sequence: MDPVPSSASHGNLDEQIAQLMQCKPLSEQEVRGLCEKAKEILMEESNVQPVKSPVTICGDIHGQFHDLAELFRIGGKCPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPQRITILRGNHESRQITQVYGFYDECLRKYGNANVWKTFTDLFDYFPLTALVESEIFCLHGGLSPSIETLDNIRNFDRVQEVPHEGAMCDLLWSDPDDRCGWGISPRGAGYTFGQDISEQFNHTNNLKLIARAHQLVMEGFNWAHDQKVVTIFSAPNYCYRCGNMASILEVDDSRERTFIQFEPAPRRGEPDVTRRTPDYFL
What are the official names of this protein?
Serine/threonine-protein phosphatase PP2A catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-2A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSP70_ENCCU
Sequence: MSNADAPSRKFSSSIIGIDLGTTNSCVSVIKDGKPVIIENQEGERTTPSVVSILKDEVVVGTQARNRILMHPRNTIFASKRLIGRKFGDPEVEKYVKGLPFDTMSHCNGDVWIRVDGKKYSPAQIGAFVLSKLKSSAEAFLSHPVARSVITVPAYFNDSQRQATKDAGRIAGLDVVRVINEPTAAALAYGLDKSARGNIAVYDLGGGTFDISILEVEDGVFHVKATNGDTFLGGEDLDNEVVKFIVEDFKQKEGIDLSNDVDALGRIKEGAEKIKKELSVSCTSKMEIPYICNSQGGPKHLCREITRSEFEQIAKKIVERTIAPCKRALADAGLDSSDIKHVILVGGMTRMPYVRRVVKEIFGIEPSTDINPDEAVANGAALQGGVLMGEIDDVLLLDVAPLSLGIELLGGVFSRVIRRNTTIPFKETQVFSTSEDNQTEVDIKVYQGERSMVADNKYLGQIKLKSIPPLPRGVPRIEVTFESDANGIYRVTAQDSITKEPQSLEIIPSSGLTEAEVERMVEESERLRHLDEMKRRKAELIVSSSELLRRPPTELERIPKNYLDRLGKVVKGEDFDLKEMEEVLLSAKKSMS
What is the function of this protein?
May act as a chaperone.
What are the official names of this protein?
Mitochondrial-type heat shock protein 70, mit-hsp70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARLY_PSEF5
Sequence: MSTDKTNQSWGGRFSEPVDAFVARFTASVTFDQRLYRHDIMGSIAHATMLAKVGVLTDAERDSIIDGLKTIQGEIEAGSFDWRVDLEDVHMNIEARLTDRIGITGKKLHTGRSRNDQVATDIRLWLRDEIDLILGEITRLQKGLLELAEREAESIMPGFTHLQTAQPVTFGHHMLAWFEMLSRDYERLVDCRKRTNRMPLGSAALAGTTYPIDRELTCQLLGFEAVGGNSLDSVSDRDFAIEFCAAASVAMMHLSRFSEELVLWTSAQFQFIDLPDRFCTGSSIMPQKKNPDVPELVRGKSGRVFGALMGLLTLMKGQPLAYNKDNQEDKEPLFDAADTLRDSLRAFADMIPAIKPKHAIMREAALRGFSTATDLADYLVRRGLPFRDCHEIVGHAVKYGVETGKDLAEMSLEELRKFSDQIEQDVFAVLTLEGSVNARNHIGGTAPAQVRAAVARGQALLASR
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA_ERYLH
Sequence: MFSGSIPALATPFRDGAFDEATFRRLVDWQIESGSSALVPCGTTGEASTLSNAEHHRVIEVCIEQAAGRVPVIAGCGSNDTRNALLHMNFSKKAGAAAGLCVAPYYNRPSQAGLIAHFSFLAENSDLPIVLYNVPSRTVTDIEDETVVELVTKYPDRIVAIKDASGDLSRVADHRMGIGRDFCQLSGNDELWLPHSAAGGSGAISVTANVAPALCAEFHSAIAANELARARELNDRLFPLHYAMFSDASPAPVKYALSRVMEEFTDEVRLPIVSASEASRKAVDEALEHAGLI
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAK_CHESB
Sequence: MAKVIGIDLGTTNSCVAVMDGKDAKVIENAEGARTTPSIVAFTDSDERLVGQPAKRQAVTNPENTFFAIKRLIGRRFEDPMVEKDKKLVPYKIVKADNGDAWVESHGTKYSPSQISAMILQKMKETAESYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVLRIINEPTAAALAYGLDKKEGKTIAVYDLGGGTFDISILEIGDGVFEVKSTNGDTFLGGEDFDMRLVNYLADEFKKEQGIDLKNDKLALQRLKEAAEKAKIELSSSSQTEINLPFITADQTGPKHLAIKLTRAKFESLVEDLVTRTIEPCRAALKDAGLSAGEIDEVVLVGGMTRMPKVQETVKNFFGKEPHKGVNPDEVVAMGAAIQAGVLQGDVKDVLLLDVTPLSLGIETLGGVFTRLIDRNTTIPTKKSQVFSTAEDNQNAVTIRVFQGEREMAADNKLLGQFDLVGIPPAPRGMPQIEVTFDIDANGIVNVSAKDKGTGKEQQIRIQASGGLSDAEIEKMVKDAEANAEADKKRRETVEVKNQAEALIHSTEKSLKDYGDKVSEDDRKAIENAIAELKTATEGEDADAIRAKTTALAEASMKLGQAVYEASQAENAAGGTEETGGAKDDVVDADFEEIDEDDKKSA
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: Y3446_MYCBO
Sequence: MRDHLPPGLPPDPFADDPCDPSAALEAVEPGQPLDQQERMAVEADLADLAVYEALLAHKGIRGLVVCCDECQQDHYHDWDMLRSNLLQLLIDGTVRPHEPAYDPEPDSYVTWDYCRGYADASLNEAAPDADRFRRR
What are the official names of this protein?
Uncharacterized protein Mb3446.
What is the protein family that this protein belongs to?
To M.leprae ML0386.
Protein: GSID_PECAS
Sequence: MRHWRRKAMLATLPVIRDKSVRTPWREFWRRFLRQHVAVAAGLFVLLLIAIAFWAQYLMPYDAENYFDYDRLNEGPSSAHWLGVDSLGRDIFSRILMGTRISLAAGIFSVLVGMMIGTTLGLLAGYYEGWADRIIMRICDVLFAFPGILLAIAVVAIMGSGMANVVVAVAIFSIPAFARLVRGNTLVLKQLTYIESARSMGANDWTILFRHILPGSVSSIVVFFSMRIGMSIITAASLSFLGLGAQPPMPEWGAMLNEARSDMVIAPHVAIFPSLAIFLTVLAFNLLGDGLRDALDPKLKS
What is the function of this protein?
Part of the ABC transporter complex GsiABCD involved in glutathione import.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Glutathione transport system permease protein GsiD.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYAS_METHJ
Sequence: MTGYTLTCPVCNKEFSDSYTLTCPGGCQGLIRAKYAARQITLHDAPGVFKYMDWLPVTGVLRTRAEPVCFKSEGLARALGLSDLWIVFSGYWPEVGAFAVSGSFKEFEAFPTMQRLSERTKGIIQVSSAGNTGRAFAEVSAETCQPVIIVVPESARDRLFTTSPAHDTLLITISGDYTDAINLGSRICTLPGIFPEGGAKNVARRDGMGTVMLAGTLAMGTLPDWYLQAVGSGTGGIAAYEASLRLIADGRFGTRMPRLLLFQNEPFIPMVRAWQEKRREIKDEDMPDAEQAISQVYSDVLTNRTPPYGIVGGVFDTLIATNGLMAGVSSADAQEAGKLFSSSEGIDPDPAAAVCVAGLMRAVRSGVIKPDEKILLNITGGGYARGRKDLPRFVKAPDIMVSKETPFEKISAKVQEWMRYYA
What is the function of this protein?
Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate.
What are the official names of this protein?
Cysteate synthase, CS, Cya synthase.
What is the protein family that this protein belongs to?
Belongs to the threonine synthase family. Cysteate synthase subfamily.