PharMolix/UniProtQA huggingface dataset:
Protein: KIL_BPMU
Sequence: MARNIKMATDAQNWLQARGSHVNESYLGVARPILEITYPPVELVKNAVRIMEHKSGVARSVWTARLNGCQIIWR
What is the function of this protein?
Expression of the kil gene induces dramatic morphological changes in the host cell, which becomes enlarged and predominantly spherical and possibly dies.  These changes might involved a direct or indirect interaction with host actin-like protein MreB.
What are the official names of this protein?
Protein kil, Gene product 5, gp5, Protein cim.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: GLGC_RHIE6
Sequence: MVEKRIQPLARDAMAYVLAGGRGSRLKELTDRRAKPAVYFGGKARIIDFALSNALNSGIRRIGVATQYKAHSLIRHMQRGWNFFRPERNESFDILPASQRVSETQWYEGTADAVYQNIDIIEDYGVEYMVILAGDHVYKMDYEWMLQQHVDSGADVTIGCLEVPRMEATGFGVMHVNDKDEILAFVEKPADPPGIPDKPDFALASMGIYVFHTKFLLDALRRDAADPNSSRDFGKDIIPYIVQNGKAVAHRFAKSCVRSDFEHEPYWRDVGTIDAYWQANIDLTAIVPELDIYDKSWPIWTYAEITPPAKFVHDDEDRRGSATSSVVSGDCIISGASLNKSLLFTGVRANSFSKLEGAVILPNVKIGRRAQLKNVVIDHGVVIPEGLVVGEDPELDAKRFRRTESGICLITQPMIDKLDI
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: Y098_GVCL
Sequence: MTGVMKVKSSVFNILRIVRYKVINETVVIVFLSKFTKHIKQMNHRWTVLRNSWSLTKRHILFVTKYSDLKDIQKELLNSVEFVVFIGDFTKSIFFSDYKMDNIVCKDEMQDFRQHFKTKYKLSYMGHIFVIPHKQPTYDLLTEWLVCNIYSLQEITNINTIYFEPPHVVVFDMDSTLITDEDQVRIRDPAIYEALDALKKYNCVLCLWSYGDKEHVVNSLNKVKLDGYFKIILSGGRKAGEYQLNEEEDRYYNVYYESTPFYLNMTDVKNIPKSPRVVLWYLINHNIVLFKTLTLVDDLFDNNIYYDNFVNLSTCPVPVNDWDKWHTQIVRFIVNYDKKFKNY
What are the official names of this protein?
Uncharacterized 41.0 kDa protein in P143-LEF5 intergenic region.
Protein: COAX_ACIB5
Sequence: MKSLWLDIGNTRLKYWITENQQIIEHAAELHLQSPADLLLGLIQHFKHQGLHRIGISSVLDTENNQRIQQILKWLEIPVVFAKVHAEYAGLQCGYEVPSQLGIDRWLQVLAVAEEKENYCIIGCGTALTIDLTKGKQHLGGYILPNLYLQRDALIQNTKGIKIPDSAFDNLNPGNNTVDAVHHGILLGLISTIESIMQQSPKKLLLTGGDAPLFAKFLQKYQPTVETDLLLKGLQQYIAHYPKD
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPPH_PSEP1
Sequence: MIDPDGFRPNVGIILTNDAGQVLWARRINQDAWQFPQGGINPDETPEDALYRELNEEVGLERDDVEILACTRGWLRYRLPQRLVRTHSQPLCIGQKQKWFLLRLLSNEQRVRMDLTGKPEFDGWRWVSYWYPLGQVVTFKREVYRRALKELAPRLLTRD
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: RL36_CAMJE
Sequence: MKVRPSVKKMCDKCKVVRRKGVVRIICENPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: M670_ARATH
Sequence: MKKYKMVINIDMLRLFLPLLGGSVSGSLFGRFLGSEGSAIMITTCVSFCALVVFIFGLFYFRKKGPLKRILYLFLVGFVLSLIRIKVVYLLGGQALPLLDPILMYAVGAGALLGPNGAESSATWEEDSFELDVLGESFSSSKTDMDSQVAEAPQTEEGEPSVNQVPQEAGASHRVGPYQDQGLATDRNGNPIDLNDSLPPSSLLYGEIESSASVRARDLELEKDIKRVQRLTRNFDNAEDPARRLEVAARLDPEVRELDQKWALFQEKDASGLGR
What are the official names of this protein?
Uncharacterized mitochondrial protein AtMg00670, ORF275.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: TBB8_ARATH
Sequence: MREILHIQGGQCGNQIGAKFWEVVCAEHGIDSTGRYQGENDLQLERVNVYYNEASCGRFVPRAVLMDLEPGTMDSVRSGPYGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELIDSVLDVVRKEAENCDCLQGFQVCHSLGGGTGSGMGTLLISKIREEYPDRMMLTFSVFPSPKVSDTVVEPYNATLSVHQLVENADECMVLDNEALYDICFRTLKLTTPSFGDLNHLISATMSGVTCCLRFPGQLNSDLRKLAVNLIPFPRLHFFMVGFAPLTSRGSQQYRALTVPELTQQMWDAKNMMCAADPRHGRYLTASAMFRGKMSTKEVDEQMINVQNKNSSYFVEWIPNNVKSTVCDIPPTGLKMASTFIGNSTSIQEMFRRVSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEEEGYEYEEDEVEVQEEQ
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta-8 chain, Beta-8-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RK16_LANPU
Sequence: MLSPKRTRFRKQHRGRMKGKSYRGNHISFGRYALQAVEPAWITARQIEAGRRAISRYARRGGKIWVRLFPDKRVTLRPAETRMGSGKGSPEYWVSVVKPGRILYEIGGVSETVARTAMLLAASKMPIRTQFIIEE
What are the official names of this protein?
50S ribosomal protein L16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: AROA_STRT2
Sequence: MKLETKAQGLRGSLRIPGDKSISHRSIMFGSLAKGVTTVRDILRGEDVLSTMQVFRDLGVTIEDDGDVVRIHGVGFDGLKAPQNKLDMGNSGTSIRLISGVLAGQDFDVEMFGDDSLSKRPMDRVTIPLRQMGVEVSGQTDRDLPPLKMHGSKSLKPIHYELPVASAQVKSALIFAALQADGESVIIEKEKTRNHTEDMIQQFGGQLQVEGKEIRISGGQTFTAQEVVVPGDISSAAFWLVAGLVVPNSKIVLKNVGINETRTGVIDVIKDMGGKIKLSDIDQVAKSATITVETSELKGTEIGGDIIPRLIDELPIITLLATQAQGKTVIRDAEELKVKETDRIQVVADALNAMGADIVPTEDGMIITGKTPLHGAEVNTFGDHRIGMMTAIAALLVQDGEVDLQRAEAINTSYPSFFSDLEGLLHG
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SBT3G_ARATH
Sequence: MELSSLIVPNNKKHFVVVFIGLVLIFKIALITAANEKSQIYTVHLGERQHDDPNIVTESHHDILGPLLGSKKASHESMIYSYRHGFSGFAAKLTSSQARELSGHPDVVRVTRSKNMKLKTTRVSDYLGLTSAAPTGLLHETDMGSEAIVGILDSGIWPDSKSFNDNGLGPIPTRWKGKCVSAEAFNASSCNRKLIGAMYYSKGLESKYNGSFNAAEKGEVMSPLDKIGHGTHCASTAVGSFVPDANVLSLAQGTARGSAPRARIASYKVCWNNEECFTPDIVKAIDHAIRDGVDVLSLSLGSEVPVDFEVDRDDFAIAAFHAVMKGIPVVCAGGNDGPEKETISNVAPWLITVAATTMDREYFTPITLGNNITLLGQEGLYIGEEVGFTDLLFYDDVTREDMEAGKATGKILLFFQRANFEDDFAAYAKSKGAVGVIIATQPTDSIDASTVDIAIAYVDNELGMDILLYIQTTKSPIAKISPTKTFVGRPLATKVARFSSRGPNSLSPVILKPDIAAPGSGILAAVPTGGGYDFMSGTSMSTPVVSGIVALLRKKRPDWSPAAIRSALVTTALQTDPSGEPIAAEGSPRKLADPFDYGGGLVNPVKVADPGLVYDMGHDEYVHYLCSAGYDNTSISKLLGEIYTCPTPIPSMLDVNMPSITIPYLSEEITITRTVTNVGPVGSVYKAVIQAPQGINLQVSPETLEFGSNTNKTTFTVKVSTTHRANTDYLFGSLTWADNEGHNVRIPLSVRTRVFNFKI
What are the official names of this protein?
Subtilisin-like protease SBT3.16, Subtilase subfamily 3 member 16, AtSBT3.16.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ENO_METVS
Sequence: MDNSFDIYEIKARQVLDSRGNPTIEAEVLTAGRGYGHAIVPSGASTGTFEAVELRDLGKKYGGKGVLNAVGNVNEIIAPELIGEDSRNQRLIDNIMINLDGTENKANLGANAILAVSMAVARAAADTSSLPLYKYLGGCNSYIMPVPMMNVLNGGKHAGNALDFQEFMIMPIGADSFSDAVRMCAETYQSLKKVISEKYGKDAVNIGDEGGFAPPVKTIDEAFSVLLEGVKRAGYENEIVFTLDSAASEFYDEKTNSYVVLGESLSTDKLIEIYKDMVSKYPIVSIEDPLFEGDFEGFKEITKELKGIQIIGDDIFVTNTNRLKKGIEMNAANALLLKVNQIGTISESIDAANLASRNGYGVIVSHRSGETEDSIISDLTVALNSGQIKTGAPARGERTAKYNQLIRIEEELQISKYAGKNFKIPF
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: SPR1_YEAST
Sequence: MVSFRGLTTLTLLFTKLVNCNPVSTKNRDSIQFIYKEKDSIYSAINNQAINEKIHGVNLGGWLVLEPYITPSLFETFRTNPYNDDGIPVDEYHFCEKLGYEKAKERLYSHWSTFYKEEDFAKIASQGFNLVRIPIGYWAFTTLSHDPYVTAEQEYFLDRAIDWARKYGLKVWIDLHGAAGSQNGFDNSGLRDSYKFLEDENLSATMKALTYILSKYSTDVYLDTVIGIELLNEPLGPVIDMERLKNLLLKPAYDYLRNKINSNQIIVIHDAFQPYHYWDGFLNDEKNEYGVIIDHHHYQVFSQVELTRKMNERIKIACQWGKDAVSEKHWSVAGEFSAALTDCTKWLNGVGLGARYDGSWTKDNEKSHYINTCANNENIALWPEERKQNTRKFIEAQLDAFEMTGGWIMWCYKTENSIEWDVEKLIQLNIFPQPINDRKYPNQCH
What is the function of this protein?
Probably involved in the processes of spore formation and contributes to ascospore thermoresistance by participating in the morphogenesis of ascospore walls.  The enzyme may do this by modifying glucan linkages in the developing ascospore wall, thus strengthening it or lending it plasticity.
What are the official names of this protein?
Sporulation-specific glucan 1,3-beta-glucosidase, Exo-1,3-beta-glucanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL31B_STRTD
Sequence: MKKDIHPDYRPVVFMDTTTGYQFLSGSTKHSNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: RUTC_ACIAD
Sequence: MPKEIILPEGTPPPLAPYVPATKADNIVYVSGILPLDENNDVVHVGDAAAQTRHVLETIKHILSNAGGSLKDVTFNHIFLRDWADYPAINQVYAEYFPEERPARYCVQVGLVKPDALIEIASVAHV
What is the function of this protein?
Involved in pyrimidine catabolism.  Catalyzes the deamination of 3-aminoacrylate to malonic semialdehyde, a reaction that can also occur spontaneously.  RutC may facilitate the reaction and modulate the metabolic fitness, rather than catalyzing essential functions.
What are the official names of this protein?
3-aminoacrylate deaminase RutC, 3-AA deaminase.
What is the protein family that this protein belongs to?
Belongs to the RutC family.
Protein: XGPT_YERPS
Sequence: MNEKYVVTWDMLQIHARKLAQRLLPAEQWKGIIAVSRGGLVPAGILARELGIRYVDTVCISSYDHDNQRDLKVLKRAEGDGEGFIVIDDLVDTGGTATAIREMYPKAHFVTIFAKPAGRPLVDDYVVDIPQNTWIEQPWDMAVTFVAPLSGK
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi.  To a lesser extent, also acts on hypoxanthine.
What are the official names of this protein?
Xanthine-guanine phosphoribosyltransferase, XGPRT, Xanthine phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y1884_BURMA
Sequence: MAGHSKWANIKHKKAAADAKRGKIWTRLIKEIQVAARLGGGDVNSNPRLRLAVDKAADANMPKDNVKRAIDRGVGGADGANYEEIRYEGYGIGGAAIIVDTLTDNRTRTVAEVRHAFSKFGGNMGTDGSVAFMFDHVGQFLFAPGTSEDALMEAALEAGANDVNTNDDGSIEVLCDWQEFSKVKDALEAAGFKAELAEVTMKPQNEVDFTGEDAVKMQKLLDALENLDDVQEVYTNAVVVEE
What are the official names of this protein?
Probable transcriptional regulatory protein BMA1884.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24E_SULTO
Sequence: MPSIKQCSFCGKEIPPATGLMYIRNDGSILWFCSNKCKKSMLKLHRDPKKLKWTKSYIGGK
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L24e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL24 family.
Protein: UREG_JANSC
Sequence: MGSVNGPLRVGIGGPVGAGKTTLTAELARAMGQAYSVAVITNDIYTSEDAEFLLRAQVLPAERIRGVETGGCPHTAIREDASINLAAIAEFRTRLPDLDVIFIESGGDNLAATFSPELADLTIYVIDTAAGQDIPRKKGPGLTRSDLLIVNKVDLAPHVGVDVAQLEADTRAARGRRAYVMGSLREGRGVPEIVQFIKEVGGL
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPOL_BPE32
Sequence: MSNPDALPFLTEMTVADIISKQAKHGVSFNRRNARWYVHLLKEIIVNIDRELIPLLPKMRLDGSTYMKPFKKSGALQKWPQAYCDRVGLKREDIGGAFTCVEYVDFDPSKDARVKEALMDEGFLPPEFNVSKKPWNTFEIKKDMRKYGTYQAWYTAWMRGNAKQKQTAEMVDADIKKFLEKHFRFKTKNYMKAYVFGLGLNPNRRNPVTFDEIKKALATSNKWPTAPTNLEETLEEGLGGELGSVGSLLKRRVVAAHRLGLISGLIAKEREDGKLSAEANSCATPTFRFKHRIVVNIPSRGLFGHECRSLFESDYNSDSDHSRPFVITNVVPDGCYIRKGTNVIYEKGKPGKKDKPVGAYKYYIPAGKEVFLGYDGSGLELRMLAHYLIKECRDMLAEAIEENNPAKKALAERGLASAIMYRDILLEGDIHSHNQKLAGLPTRDNAKTFIYAFNYGAGDAKLGSIVGGGADEGSVMRARFLAENPCIAILIDRMTEKAAQGYLIGVDGRKITMRRDATGKVMVHKALNTLLQCAGAVVMKYAMMFLNKWIEKDKVRCAKVIDMHDEGQFSVNRNDVQKLKEHTELCVKKAGEYLNMECPLASDCQIGLNWMHTH
What is the function of this protein?
Replicates viral genomic DNA.  This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'-5' direction.
What are the official names of this protein?
DNA-directed DNA polymerase, DNA polymerase gp53.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-A family.
Protein: Y1935_SYNC1
Sequence: MKRARLIIITGLSGSGKTTAARALEDEGFFVVDNLPLVLLPEFLKLHAGSAVAGSNVAVVVDVRNKPYLEGYKQTLAEVRSAGHVVDIFFFDAVDDVLLRRYSETRRRHPLSQKEGVAESIRQERALLGGIMDLSTEIIDSSWLTPHQLRARVVHMVCGDDKGNPLAVLVQSFGYRYGIPQGSDLVMDVRFLPNPHFVPDLRPQTGLSQGVRDFVLGQPACREFLDRFNHLLDYLLPSYRKEGKSYLTISIGCTGGRHRSVAIAEHLRYAIQGEDMVVDGLHRDVAKE
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Pcar_1935.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: AURKB_DANRE
Sequence: MQNKENREPRVQQTPSAGVGPLRVEMNPDTHAVSGPGRVPVKSNSKVLSIDDFDIGRPLGKGKFGNVYLARERKLKVVIALKVLFKSQMVKEGVEHQLRREIEIQSHLRHPNILRFYNYFHDDTRVFLILEYAPRGEMYKELQRYGRFDDQRTATYMEEVSDALQYCHEKKVIHRDIKPENLLLGYRGELKIADFGWSVHAPSLRRRTMCGTLDYLPPEMIEGHSHDEKVDLWSIGVLCYECLVGNPPFETASHAETYKRITKVDLQFPKLVSEGARDLISKLLRHSPSMRLPLRSVMEHPWVKANSRRVLPPVCSSEPH
What is the function of this protein?
Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis (By similarity).  The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly (By similarity).  Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis (By similarity).  Required for central/midzone spindle assembly and cleavage furrow formation (By similarity).  Key component of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage (By similarity).  Phosphorylates 'Ser-10' of histone H3 during mitosis (By similarity).
What are the official names of this protein?
Aurora kinase B, Serine/threonine kinase A, Serine/threonine-protein kinase 12, Serine/threonine-protein kinase aurora-B.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Chromosome, centromere. Cytoplasm, cytoskeleton, spindle. Midbody. Note=Localizes on chromosome arms and inner centromeres from prophase through metaphase and then transferring to the spindle midzone and midbody from anaphase through cytokinesis. Localization (and probably targeting of the CPC) to the inner centromere occurs predominantly in regions with overlapping mitosis-specific histone phosphorylations H3pT3 and H2ApT12.
Protein: TDIA_EMENI
Sequence: MAPSKTEIAPLRAAKYPFGNIVDALRHAAAHTDEGIIVYHPNSISTSSPPQTVSYKDLLHQAEANATRLLQQKLCSPKSIVLVHFESALDSIVWYWSVLLAGGIPALTGPGMFSQNPADRERHLRHLSETLNSPVCLTRPALLAPFEEQTADDRIKARTVDEILAAPEIADVADAPLPALTPSSTDMLALMLTSGSSGNAKAVPLTHQQLLAAFRGKSTAASLRFPRSPFLSWVHMDHVANLVHCHIFAIVSGISQIQVPAPDLLINPAQLLNLISRHRVSRTFMPNFLCAKLRRQLESGSPEYILDPGLNLETLYIDTGGEANVTEVCIALQSLLSRYGAPDNVFKPSFGMTETVAGCIFNSHCPSYDHAQRHEFACLGKPMPGVRMRVTRLDTPSEEAAPGERGSLEVTGEVVFKGYYNNPAATAEAFTSDGWFRTGDLAFIDSNGNLHLDGRTKEMININGVKYLPYELDAALEQAQIPGATPSYFCTFSSRDATMDTEVVVVLYLPSYVESDDEARFSTQSSIIRVVAMHTRSRPRVVPLRPQDMPKSTLGKLSRAKLKTALEEGQFATQQQINDEAIRRYQQKTRASPETPDEAVILDIIKEQLEIRSDDDSFGVNDSILSIGATSMDLVAIIHRINKCLQPSQPLRLTDILKDSTARGLAVALATGAAPRSQDQSSTHVYDPVVTLQPHGTKSPLWLVHPGVGEVLVFVNLAHHITDRPVYAFRAKGFNAAAGLPETPFTSLEELFTTYRDAIKERQPHGPYAIAGYSFGGMVAFEVSKLLEQDGDEVRYCGSWNLPPHIKFRMRELVWEECVIHLFYFVGLMTELAAYTHKPTLQEFNRANRRLDAIRYLRQHCDAARWDELGLSEEYYLLWVGLASNMQSLAVDYEPSGSVKCMDVFVADPLSHVAKDRIDWVEGRLSAWKEFVREDVRFHDVQGAHYTMLNREYVEAFAGTLKNVLRERGL
What is the function of this protein?
Didemethylasterriquinone D synthetase; part of the gene cluster that mediates the biosynthesis of terrequinone A, an antitumor agent (PubMed:17704773, PubMed:16426969, PubMed:17291795, PubMed:22083274).  The first step in the biosynthetic pathway for terrequinone A is formation of indole pyruvic acid (IPA) from L-tryptophan by the aminotransferase tdiD (PubMed:17704773).  The nonribosomal peptide synthase tdiA then immediately converts unstable IPA to didemethylasterriquinone D (DDAQ D), via condensation of 2 IPA molecules (PubMed:17704773).  The symmetric connectivity of the 2 IPA molecules is thought to arise by head-to-tail dual Claisen condensations facilitated by the TE domain (PubMed:17704773).  TdiB then catalyzes reverse prenylation by transferring dimethylallyl diphosphate to carbon atom 2' of DDAQ D, to yield asterriquinone C-1 (PubMed:18029206).  Finally, tdiC and tdiE enzymes robustly convert asterriquinone C-1 to terrequinone A via a transformation involving regular prenylation at carbon atom 5, which requires elimination of the hydroxy group on C-5 (PubMed:17704773, PubMed:18029206).
What are the official names of this protein?
Didemethylasterriquinone D synthetase tdiA, Nonribosomal peptide synthase tdiA, Terrequinone biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: MOAA_SALTI
Sequence: MASQLTDAFARKFYYLRLSITDVCNFRCTYCLPDGYKPGGVTNNGFLTVDEIRRVTRAFASLGTEKVRLTGGEPSLRRDFTDIIAAVGENDAIRQIAVTTNGYRLARDAANWREAGLTGVNVSVDSLDARQFHAITGQDKFRQVMAGIDAAFDAGFEKVKVNTVLMRDVNHHQLDTFLAWIQPRPIQLRFIELMETGEGSDLFRKHHISGQVLRDELIKRGWIHQLRQRSDGPAQVFCHPDYAGEIGLIMPYEKDFCATCNRLRVSSVGKLHLCLFGDGGVSLRDLLQDDAQQYALEERISDALREKKQTHFLHQSNTGITQNLSYIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: CH10_ECO27
Sequence: MNIRPLHDRVIVKRKEVETKSAGGIVLTGSAAAKSTRGEVLAVGNGRILENGEVKPLDVKVGDIVIFNDGYGVKSEKIDNEEVLIMSESDILAIVEA
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
Protein: YLHA_CAEEL
Sequence: MSKYESEFSCQDKFSVFYGTVATLFFTAMTTLTCPFQQLFIFLAFFEFAVVALYVCKSRFLQVLHFQYQSVAYCVPIFLFVTSIYYEFYPKETHEFLESFNFKIVKDFIEEIPIFFPSALWFLWTTRLFHTHTVLVRLNTEYRLDDPKSHDLGPIRQSSFHSSLNIAAITFFSILAYSGNESIENICFWIAIFELIMTVTYVFNNSWIMMIHFVGQAIVFSVIFFLLCCLLAYEYSPVAALEFLDSYGLVQVKSYVVRSPFFVASALSAVWFSRMMATHVFLVEVATDTRIHRHQMSNHFNRLIQNI
What are the official names of this protein?
Uncharacterized protein C48B4.11.
Protein: PFKA_ASPFU
Sequence: MSSTQAPVEPPKRRRIGVLTSGGDAPGMNGAVRAVVRMAIYSDCEAYAVFEGYEGLVHGGHMIRQLHWEDVRGWLSKGGTLIGSARSMAFRERAGRLKAAKNMVLRGIDALVVCGGDGSLTGADVFRSEWPGLLEELVKNGELTEEQIEPYKVLNIVGLVGSIDNDMSGTDATIGCYSSLTRICDAVDDVFDTAFSHQRGFVIEVMGRHCGWLALMSAISTGADWLFIPEMPPRDGWEDDMCSIITKNRKERGKRRTIVIVAEGAQDRSLNKISSSTVKDILTQRLGLDTRVTVLGHTQRGGPACAYDRWLSTLQGVEAVRAVLDMKPDSPSPVITIRENKIMRTPLVDAVQETKHVAKLIHDKDFEAAMRLRDAEFKEYHFAYRNTATPDHPKMILPQDKRMRIAIIHVGAPAGGMNQATRAAVGYCLTRGHTPLAIHNGFPGLCRHHDDQPVGSVREVKWLESDAWVNEGGSDIGTNRSLPSEDFETTAMCFEKYKFDALFVVGGFEAFTAVSQLRQARDKYPAFKIPMVVLPATISNNVPGTEYSLGSDTCLNTLIDFCDAIRQSASSSRRRVFVIETQGGKSGYIATTAGLAVGATAVYIPEEGIDIKMLSNDIDFLRENFARDKGANRAGKLILRNECASSTYTTQVIADIFKEEAKGRFESRSAVPGHFQQGGKPSPMDRIRALRMAVKCMLHLENYAGKSRDEIAADPMSAAVIGIKGSQVLFSAMGGEDGLEATETDWARRRPKTEFWLELQNYVNVLSGRASAGKPLWSCYESKHFPSCCRLYNTDLSIDIDPSALTSS
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_CAUSK
Sequence: MTQSSPQNLILVGRVAGAFGVRGELRIATYTEDPLTLTRFKALTRQDGSPALTVQTARVVKDGVVARCAGVDTKEAADALRGLRLYVPRAALPEPDEDEYYLADLIGLPVRHVATDELLGKIKSVQNFGADDLLEIDPALGGQTWYLPFTRAAVPEVKIADGVVLADPPALVGEPEGPESPAEDDDGERHYD
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.