PharMolix/UniProtQA huggingface dataset:
Protein: AGO2_DROME
Sequence: MGKKDKNKKGGQDSAAAPQPQQQQKQQQQRQQQPQQLQQPQQLQQPQQLQQPQQQQQQQPHQQQQQSSRQQPSTSSGGSRASGFQQGGQQQKSQDAEGWTAQKKQGKQQVQGWTKQGQQGGHQQGRQGQDGGYQQRPPGQQQGGHQQGRQGQEGGYQQRPPGQQQGGHQQGRQGQEGGYQQRPSGQQQGGHQQGRQGQEGGYQQRPPGQQQGGHQQGRQGQEGGYQQRPSGQQQGGHQQGRQGQEGGYQQRPPGQQQGGHQQGRQGQEGGYQQRPPGQQQGGHEQGRQGQEGGYQQRPSGQQQGGHQQGRQGQEGGYQQRPSGQQQGGHQQGRQGQEGGYQQRPSGQQQGGHQQGRQGQEGGYQQRPPGQQPNQTQSQGQYQSRGPPQQQQAAPLPLPPQPAGSIKRGTIGKPGQVGINYLDLDLSKMPSVAYHYDVKIMPERPKKFYRQAFEQFRVDQLGGAVLAYDGKASCYSVDKLPLNSQNPEVTVTDRNGRTLRYTIEIKETGDSTIDLKSLTTYMNDRIFDKPMRAMQCVEVVLASPCHNKAIRVGRSFFKMSDPNNRHELDDGYEALVGLYQAFMLGDRPFLNVDISHKSFPISMPMIEYLERFSLKAKINNTTNLDYSRRFLEPFLRGINVVYTPPQSFQSAPRVYRVNGLSRAPASSETFEHDGKKVTIASYFHSRNYPLKFPQLHCLNVGSSIKSILLPIELCSIEEGQALNRKDGATQVANMIKYAATSTNVRKRKIMNLLQYFQHNLDPTISRFGIRIANDFIVVSTRVLSPPQVEYHSKRFTMVKNGSWRMDGMKFLEPKPKAHKCAVLYCDPRSGRKMNYTQLNDFGNLIISQGKAVNISLDSDVTYRPFTDDERSLDTIFADLKRSQHDLAIVIIPQFRISYDTIKQKAELQHGILTQCIKQFTVERKCNNQTIGNILLKINSKLNGINHKIKDDPRLPMMKNTMYIGADVTHPSPDQREIPSVVGVAASHDPYGASYNMQYRLQRGALEEIEDMFSITLEHLRVYKEYRNAYPDHIIYYRDGVSDGQFPKIKNEELRCIKQACDKVGCKPKICCVIVVKRHHTRFFPSGDVTTSNKFNNVDPGTVVDRTIVHPNEMQFFMVSHQAIQGTAKPTRYNVIENTGNLDIDLLQQLTYNLCHMFPRCNRSVSYPAPAYLAHLVAARGRVYLTGTNRFLDLKKEYAKRTIVPEFMKKNPMYFV
What is the function of this protein?
Essential for RNA interference (RNAi); double-stranded RNA induces potent and specific gene silencing (PubMed:11498593, PubMed:12368261, PubMed:14508492, PubMed:32504809).  RNAi is mediated by the RNA-induced silencing complex (RISC), a sequence-specific, multicomponent nuclease that destroys or silences messenger RNAs homologous to the silencing trigger (PubMed:11498593, PubMed:12368261, PubMed:14508492).
What are the official names of this protein?
Protein argonaute-2.
What is the protein family that this protein belongs to?
Belongs to the argonaute family. Ago subfamily.
What are the subcellular locations of this protein?
Cytoplasm, Cytoplasmic ribonucleoprotein granule.
Protein: RSMJ_VIBA3
Sequence: MQLQLICEDATQIDHLNDLATRWNLSHDENSDFALVLTCERLELRKVDEPKLGAIFVDLVGGAVGHRRKFGGGKGQAIAKAAGLNKGATPTILDGTAGLGRDAFVLASLGCKVQMVERHPVVAALLDDGLQRAQKDPDIGGWVSERMKLIHASSHDALDKLSNDPNFEQPDVVYLDPMYPHPENKKKSALVKKEMRVFQSLVGADLDADGLFEPAMKLATKRVVVKRPDYAAWLDEQKPSMAIETKKNRFDVYVKASMT
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDIB_BPSPB
Sequence: MTYESKTGNVKRFVKALQQEFDVEAIEITDDTIINQEFIHITYTIGFGEVPERTLSFINKNKNKIRGVAVSGNKVWGDNYGLAGDKLSAKFHTPLLLKFELSGTKQDLQKIIQEVQLIDKHNTKLDQAQ
What is the function of this protein?
Not known; probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Phage protein nrdI, BnrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: UPP_MYCPN
Sequence: MIKKVHHALIENELTKLRDKSSSSSQFRMALSQITSLLFFEVTKESPLEEIVVKTPFTKTKGYKLKNEIVLVPIMRAGLGMVDPIVRYSEKIRVGHLGIYREHEGTNVISYYKKMPENIGNSHVIILDPMLATGTTLATAISSIKKNHPIKISVVAIVAAPEGIKAVEAAHPDVDIYLAAIDEKLNKDNYIIPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: HFB4A_ORYSJ
Sequence: MEWEEESEAARQKAAAASASVVPAPFLTKTYQLVDDPATDHVVSWEDDDGGESASSFVVWRPPEFARDILPNYFKHSNFSSFVRQLNTYGFRKVVPERWEFANEFFRKGEKQLLCEIHRRKSAAATWPPFPPPPPPFFAPRHFAAGAFFRHGDGMLHGRLGALVTTTERRHWFESAALPVAPSSRLLSQLGPVIAPARRAAATPEEEALMQENHRLLRGNAALVQELAHMRKLYSDIIYFVQNHVRPVAPSPAAAAALHGLGVLRPPPAGGKAPASEVRGASGRSATSSSSLTVAEDQPTLLALRLPRTTEKIINEVSGGNGGGSTKLFGVHLSSADEQTSSGASRKRSPPQEQPPTSPAPKRTLVVEHSELRLSIVSPP
What is the function of this protein?
Transcriptional regulator that specifically binds DNA of heat shock promoter elements (HSE).
What are the official names of this protein?
Putative heat stress transcription factor B-4a, Heat stress transcription factor 20, OsHsf-20.
What is the protein family that this protein belongs to?
Belongs to the HSF family. Class B subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: TAT_SIVMB
Sequence: MEPIDPNLEPWNHPGSQPKTACNNCYCKQCCYHCQLCFTKKGLGISYGRRKRKQRRRTSESSQNHQDPVPKQPLSQPGGIETGQKKSKKEVESQTTSDQFA
What is the function of this protein?
Extracellular circulating Tat can be endocytosed by surrounding uninfected cells via the binding to several surface receptors such as CD26, CXCR4, heparan sulfate proteoglycans (HSPG) or LDLR.  Neurons are rarely infected, but they internalize Tat via their LDLR.  Through its interaction with nuclear HATs, Tat is potentially able to control the acetylation-dependent cellular gene expression.  Modulates the expression of many cellular genes involved in cell survival, proliferation or in coding for cytokines or cytokine receptors.  Tat plays a role in T-cell and neurons apoptosis.  Tat induced neurotoxicity and apoptosis probably contribute to neuroAIDS.  Circulating Tat also acts as a chemokine-like and/or growth factor-like molecule that binds to specific receptors on the surface of the cells, affecting many cellular pathways.  In the vascular system, Tat binds to ITGAV/ITGB3 and ITGA5/ITGB1 integrins dimers at the surface of endothelial cells and competes with bFGF for heparin-binding sites, leading to an excess of soluble bFGF.
What are the official names of this protein?
Protein Tat, Transactivating regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the lentiviruses Tat family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Secreted. Note=Probably localizes to both nuclear and nucleolar compartments. Nuclear localization is mediated through the interaction of the nuclear localization signal with importin KPNB1. Secretion occurs through a Golgi-independent pathway. Tat is released from infected cells to the extracellular space where it remains associated to the cell membrane, or is secreted into the cerebrospinal fluid and sera. Extracellular Tat can be endocytosed by surrounding uninfected cells via binding to several receptors depending on the cell type.
Protein: OL154_MOUSE
Sequence: MMHRNQTVVTEFFFTGLTSSFHLQIVLFLTFLCVYLATLLGNLGMIILIHLDTRLHIPMYFFLSHLSFVDACSSSVISPKMLSDMFVDKKVISFLGCAIQLCLFSQFVVTECFLLASMAYDRYVAICKPLLYTLIMSQRVCVQLVIGPYSIGFVSTMVHIISAFVLPYCGPNLINHFFCDLLPVLSLACANTQMKKRLLFIVAGILGVFSGIIILVSYVYIAITILKISSADGRRKAFSTCSSHLTAVSILYGTLFFIYVRPSSSFSLDINKVVSLFYTTVIPMLNPFIYSLRNKEVKDALIRTFEKQFCYSFQDKIL
What is the function of this protein?
Potential odorant receptor.
What are the official names of this protein?
Olfactory receptor 154, Olfactory receptor 175-1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RTF1_YEAST
Sequence: MSDLDEDLLALAGADESEEEDQVLTTTSAKRAKNNDQSLSKKRRIEVGSVEDDDEEDDYNPYSVGNADYGSEEEEEANPFPLEGKYKDESDREHLESLPEMERETLLFERSQIMQKYQERKLFRARGRDMKEQQQRAKNDEDSRKTRASTRSTHATGHSDIKASKLSQLKKQRARKNRHYSDNEDEDDEEDYREEDYKDDEGSEYGDDEEYNPFDRRDTYDKREEVEWAEEEDEQDREPEISDFNKLRIGRSFVAKFCFYPGFEDAVKGCYGRVNVGTDKRTGKTSYRMVRIERVFLQKPYNMGKFYTNQYFGVTQGKDRKVFQMNYFSDGLFAEDEYQRYLRALDNSQMIKPSLHSLSNKTKEVMDFVNTPLTDKTTDEVVRHRMQFNKKLSGTNAVLEKTVLREKLQYAKETNNEKDIAKYSAQLRNFEKRMSVYEKHHENDQSDIKKLGELTSKNRKLNMSNIRNAEHVKKEDSNNFDSKSDPFSRLKTRTKVYYQEIQKEENAKAKEIAQQEKLQEDKDAKDKREKELLVAQFRRLGGLERMVGELDIKFDLKF
What is the function of this protein?
The PAF1 complex is a multifunctional complex.  Involved in transcription initiation via genetic interactions with TATA-binding proteins.  Involved in elongation.  It regulates 3'-end formation of snR47 by modulating the recruitment or stable association of NRD1 and NAB3 with RNA polymerase II.  Also has a role in transcription-coupled histone modification.  Required for activation of RAD6 ubiquitin conjugate and the BRE1 ubiquitin ligase which ubiquitinate 'Lys-126' histone H2B.  Activates the SET1 histone methyltransferase complex for methylation of 'Lys-4' of histone H3 and for methylation of 'Lys-73' of histone H3 by DOT1 and 'Lys-36' of histone H3 by SET2.  Important for TATA site selection by TBP.  Directly or indirectly regulates the DNA-binding properties of SPT15, the TATA box-binding protein, and the relative activities of different TATA elements.
What are the official names of this protein?
RNA polymerase-associated protein RTF1.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm.
Protein: PATR_MYCBT
Sequence: MTARLRPELAGLPVYVPGKTVPGAIKLASNETVFGPLPSVRAAIDRATDTVNRYPDNGCVQLKAALARHLGPDFAPEHVAVGCGSVSLCQQLVQVTASVGDEVVFGWRSFELYPPQVRVAGAIPIQVPLTDHTFDLYAMLAAVTDRTRLIFVCNPNNPTSTVVGPDALARFVEAVPAHILIAIDEAYVEYIRDGMRPDSLGLVRAHNNVVVLRTFSKAYGLAGLRIGYAIGHPDVITALDKVYVPFTVSSIGQAAAIASLDAADELLARTDTVVAERARVSAELRAAGFTLPPSQANFVWLPLGSRTQDFVEQAADARIVVRPYGTDGVRVTVAAPEENDAFLRFARRWRSDQ
What is the function of this protein?
May catalyze the transamination reaction in phenylalanine biosynthesis.
What are the official names of this protein?
Putative phenylalanine aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
Protein: LOXL1_HUMAN
Sequence: MALARGSRQLGALVWGACLCVLVHGQQAQPGQGSDPARWRQLIQWENNGQVYSLLNSGSEYVPAGPQRSESSSRVLLAGAPQAQQRRSHGSPRRRQAPSLPLPGRVGSDTVRGQARHPFGFGQVPDNWREVAVGDSTGMARARTSVSQQRHGGSASSVSASAFASTYRQQPSYPQQFPYPQAPFVSQYENYDPASRTYDQGFVYYRPAGGGVGAGAAAVASAGVIYPYQPRARYEEYGGGEELPEYPPQGFYPAPERPYVPPPPPPPDGLDRRYSHSLYSEGTPGFEQAYPDPGPEAAQAHGGDPRLGWYPPYANPPPEAYGPPRALEPPYLPVRSSDTPPPGGERNGAQQGRLSVGSVYRPNQNGRGLPDLVPDPNYVQASTYVQRAHLYSLRCAAEEKCLASTAYAPEATDYDVRVLLRFPQRVKNQGTADFLPNRPRHTWEWHSCHQHYHSMDEFSHYDLLDAATGKKVAEGHKASFCLEDSTCDFGNLKRYACTSHTQGLSPGCYDTYNADIDCQWIDITDVQPGNYILKVHVNPKYIVLESDFTNNVVRCNIHYTGRYVSATNCKIVQS
What is the function of this protein?
Active on elastin and collagen substrates.
What are the official names of this protein?
Lysyl oxidase homolog 1, Lysyl oxidase-like protein 1, LOL.
What is the protein family that this protein belongs to?
Belongs to the lysyl oxidase family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: FRSA_YERPN
Sequence: MAQANLSEILFKPKFKHPETSTLVRRTHCNHVVNIHSALDGDTANHWYRMINRLMWTWRGIDPLEIEEVLSRIACSKAEHSNNELLDTVVGYRNGNWIYEWANQGMMWQQKAMEETDPGSAGQFWLNAANLYSIASYPHLKGDELSEQAEVLSNRAYEEAAKYLPYTLKELTFPISDGGSLSGFLHMPTVGSAPFPTVLMCGGLDTLQSDYHRLFRDYLEPKGIAMLTIDLPSVGASSRWKLTQDTSYLHQQVLQALADVPWVDHQRVSVFGFRFGANVAVRLGYLEPQRVRAVACLGPIVHHLLCNSDSLRKVPDMYMDVMASRLGMADSTDETLNTEMNRYSLKTQGLLGRRCQTPMLAGFWENDPFSPKEEAKLICSSSADGKLLAIPSKPLYENFHRALLQTSEWLEDKMR
What is the function of this protein?
Catalyzes the hydrolysis of esters.
What are the official names of this protein?
Esterase FrsA.
What is the protein family that this protein belongs to?
Belongs to the FrsA family.
Protein: YPMF_ECOLX
Sequence: MCSPAGPVSVDHSARLILLAWRQTEQGAVVVAFKVRIHCRHEPILRPLAAVHLGQNHGPHQHLAPCFVLALLLLFPCPHPLNFGIDSRSLFFELGQPIRRLVAPLNHLDTPLLMCCLVGYHGGTAAAIPTLLCRGGRTYRFLFEKLA
What are the official names of this protein?
Uncharacterized mobilization operon protein F.
Protein: P32_MYCGA
Sequence: MFSLKKLKSKLVGVSFVFSGVIALGTGVGLTSEHKYEHSPTLVLHEGETNSVGPRKITSEPWFYPVVGAGAGLIVVSLLLGLGIGIPIAKKKERMMIQEREEHQKMVESLGIIEEQNKTEAIEPTEEVNTQEPTQPAGVNVANNPQMGINQPQINPQFGPNPQQRINPQCFGGPMQPNQMGMRPGFNQMPPQMGGMPPNQMGMRPGFNQMPPQMGGMPPRPNFPNQMPNMNQPRPGFRPQPGGGVPMGNKAGGGFNHPGTPMGPNRMNFPNQGMNQPPHMAGPRAGFPPQNGPR
What is the function of this protein?
Adhesin necessary for successful cytadherence and virulence.
What are the official names of this protein?
P32 adhesin, Cytadhesin P32.
What are the subcellular locations of this protein?
Cell projection, attachment organelle membrane; Multi-pass membrane protein. Note=Integral and surface exposed membrane protein that localizes to the membrane at the attachment organelle.
Protein: HIS6_SOLUE
Sequence: MLAKRIIPCLDVTGGRVVKGVNFVNLRDAGDPVELADRYNLDGADELVFLDITASSDARDIMADVVARTARKVFIPLAVGGGIRSIADARHILLSGADKVSVNTAAVRRPELITELSRELGAQAVVLAIDARRHGPGGWHVYTRGGRDDEGMDAVAWAARGEALGAGEVLLTSMDTDGVQDGFDCALTMAVSRATHIPVIASGGAGKPEHFVRVLTDGCADAALAASIFHYGTYTVNQLKEALDKRGIPVRVTA
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_BORA1
Sequence: MSNGTIVQCIGAVVDIQFPRDQMPKIYEALTLADEGSSFAEQGLTFEVQQQLGDGVVRTIALGSSDGLRRGMPVSRTGAPISVPVGHGTLGRIMDVLGRPIDEAGPINADEKRAIHQHAPKFDELSPSVELLETGIKVIDLVCPFAKGGKVGLFGGAGVGKTVNMMELINNIAKQHSGLSVFAGVGERTREGNDFYHEMEESNVLDKVAMVFGQMNEPPGNRLRVALTGLTMAEKFRDEGRDILFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSIQAVYVPADDLTDPSPATTFQHLDSTVVLSRDIAALGIYPAVDPLDSSSRQLDPQVVGEEHYQVARGVQQTLQRYKELRDIIAILGMDELSPEDKQAVARARKIQRFLSQPFHVAEVFTGSPGKYVPLAETIRGFKMIVEGECDALPEQAFYMVGTIDEAFEKAKKLQ
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: BIOF_ECO5E
Sequence: MSWQEKINAALDARRAADALRRRYPVAQGAGRWLVADDRQYLNFSSNDYLGLSHHPQIIRAWKQGAEQFGVGSGGSGHVSGYSVAHQALEEELAEWLGYSRALLFISGFAANQAVIAAMMAKEDRIVADRLSHASLLEAASLSPSQLRRFVHNDVTHLARLLASPCPGQQLVVTEGVFSMDGDSAPLAEIQQVTQQHNGWLMVDDAHGTGVIGEQGRGTCWLQKVKPELLVVTFGKGFGVSGAAVLCSSTVADYLLQFARHLIYSTSMPPAQAQALRASLAVIRSDEGDARREKLAALITRFRAGVQDLPFTLADSCSAIQPLIVGDNSRALQLAEKLRQQGCWVTAIRPPTVPSGTARLRLTLTAAHEMQDIDRLLEVLHGNG
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: ATPE_LACCB
Sequence: MAETSNVLRVNIVTPDGLVYDHHARMLVVHSVAGELGIMANHEPIVTPLEIGEVDVQRVDASDHNDSIAVNGGFMEVSENVASIVADSAERERDIDLSRAQAARDRAQKRIAQAKNDHNQDDLRRAQVALRRAINRINVKTSH
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ISPF_MYCTA
Sequence: MNQLPRVGLGTDVHPIEPGRPCWLVGLLFPSADGCAGHSDGDVAVHALCDAVLSAAGLGDIGEVFGVDDPRWQGVSGADMLRHVVVLITQHGYRVGNAVVQVIGNRPKIGWRRLEAQAVLSRLLNAPVSVSATTTDGLGLTGRGEGLAAIATALVVSLR
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: COXX_STAEQ
Sequence: MNKDQTLSHTTGRVSFKELQQIIKMGLVQGNLIPAFAGAWLAIVMTNHSFLSSIPQILLMLVGSTLIMGGACALNNYYDQDIDRIMPSKQSRPTVNDRISDRNLLMLSFGMMLIGEACLFLLNIPSGVLGLIGIVGYVSYYSIWSKRHTTWNTVVGSFPGAVPPLIGWVAIDGSLSLAAVALFLVVFCWQPIHFYALAIKRSDEYALANIPMLPSVKGFKRTRVSMFIWLVLLLPLPFLLSNLGVTFVVIATLLNLGWLALGFTTFRKESNQTKWATQMFVYSLNYLVVFFALVVVVSLIKMI
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RECF_BRUME
Sequence: MEAKDHIERRPDRVSIRRLKLVNFRNYAELSLPLGPGHVVLTGENGSGKTNLIEAISFLSPGRGLRRAAYDDVARANAEGGFAIHAALDCMIYGDAEIGTGTAGGGEGGRKVRINRIAASADDLLDYARILWVVPSMDGLFTGGASDRRRFLDRMVLAIDTAHGKRVLDYEKAMRSRNRLLNDGSNDDQWLDAIENQMAELGTAIAAARAQAMRLIAAMIERLPAEGPFPKADCFLEGALESRIGVEAALDLEEDFRRTLRDGRARDRAAGRTLDGPHRTDLIVQHRPKSMPAALCSTGEQKALLIGLILAHARLTAELSGMAPILLLDEIAAHLDMGRRAALFGILDELGGQAFMTGTDRALFDALAGDAQFFNVSAGQLTGI
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PFF1_PHANO
Sequence: MARLNPLSFTPGPVIFFTCAVYIALFAALLTVHLRVPDYPSKTPDGVNLTQAWSDLEKITRRFHPYNSHANDDVRDYLLTRVKSIIASKKLGGDQVELIDDNESNATFSSGSTTVYFEGTNIIVAIRGSEDDEPYHSPQSSPPGERRLDNGGVLVNAHYDSVSSGYGATDDGVGVVTVLQLLSYFTESKNWPKRTVILLLNNGEEDFLNGAKAFMRHPISQIAHTFVNLEGAGAGGRATMFRSTDTEVTRYYKASSHPFASVVSGDGFKKRLIRSETDYKVFYEELGLRGLDIAFMEPRARYHTVEDSTRETSLNSVWHMLSAAIATTSGLASDTSEQFSGSEDEHEPYTGKVKTGHGTDAVWFDLFGKVFVVFQLHTMFALCVTLLVVAPLFLIGLTFGLSKADKNYLFARKAYMYSSDDDHPVHLYGWRGFFRFPIVFSIATAVVVGLAYLMVRLNPLILYSSPYAVWSMMLSAWFSVAWFFSRGASAMRPSALQRMYALIWLFAGSFALLAFVTVLSNNYQVAGGYFALFYFAGIFLALVLSYLELFFAPTKTAFARYSAQGDEPVSRPLTGTTTAARSEEPPIADDDATETTSLLRGDRRSFARHSGRRDSIDDENGNRDEEPVQLDLKQPYPGEQDWSGKLPGWLWLLQLLLVAPIVVILVGQIALLLTSALHQTPADGNSSLFVYLAFALLTTLLLAPIGPFIHRFTWHVPTFVFLVCVATVIYNLVAFPFSREHRLKVYFVQQVDLATGNNRVSLTGVDGYVQRIVADLPSAQGEQINCTTPEAANRKELMTCTWPGLPAQVVTRASRFSNKTDTDGWLDFSITTSNKTNEATISVAGQNTRACRIVVDSHHSGVTNVTVAGAVSDPRFKAVGETGSREIRLWHREWSHPWNVSVTWPRENSKPSGRIICLWSDANAGDIPAFDEVQHYLPVWAIPSKISDGLVEGFKYFQV
What is the function of this protein?
May be involved in vacuolar sorting and osmoregulation.
What are the official names of this protein?
Vacuolar membrane protease, FXNA-related family protease 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: PRMA_KLEP7
Sequence: MPWIQLKLNTTGANAEDLSDALMEAGSVSITFQDTHDTPVFEPLPGETRLWGDTDVIGLFDAETDMKAVVAQLEQHPLLGAGFAHKIEQLEDKDWEREWMDNFHPMRFGERLWICPSWRDVPDENAVNVMLDPGLAFGTGTHPTTSLCLQWLDGLDLNGKTVIDFGCGSGILAIAALKLGAAKAIGIDIDPQAIQASRDNAQRNGVSERLELYLPQDQPESMKADVVVANILAGPLRELAPLISVLPVSGGLLGLSGILASQAESVCEAYADLFALDPVVEKEEWCRITGRKN
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KYNU_MYXXD
Sequence: MTTPYLFEDSESFARKLDAEDALRGYRDAFHFPPGPDGKPVVYLAGNSLGLQPRNAARYIQEELEDWARLGVEGHHHGRHPWLHYHELVTEHAARLVGAKPLEVVVMNTLSVNLHLMMVSFYRPTKQRFKILVEAGAFPSDQYAVASQVRFHGYDAREAVLELKPREGEETLRTEDILETIERHGHEVALVMLGSVNYLTGQAFDLAAITKAAHAKGCFVGFDLAHGAGNLRLSLHDDGPDFAVWCSYKYLNAGPGALGGVFVHERHAHTKDLPRFEGWWGHDKQTRFQMGPTFSALPGAEGWQLSNPPIFQLAALRASLELFDQAGMAALRAKSERLTGYLEFLLDRLPEGFVRITTPRDVKQRGAQLSLRFRGEPQGLLKRLGDAGIICDFRKPDIIRAAPAPLYNSFTDVYRFVKTLEGHARE
What is the function of this protein?
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
What are the official names of this protein?
Kynureninase, L-kynurenine hydrolase.
What is the protein family that this protein belongs to?
Belongs to the kynureninase family.
Protein: C90A4_ORYSI
Sequence: MAAAALLLLAAAAAAVVVAMALRWLLLLGGPAAGRQGKRARMPPGSTGLPLIGETLRLISAYKTPNPEPFIDERVARHGGVFTTHVFGERTVFSADPAFNRLLLAAEGRAVHSSYPSSIATLLGARSLLLTRGAAHKRLHSLTLTRLGRPASPPLLAHIDRLVLATMRQWEPAATVRLMDEAKKITFNLTVKQLVSIEPGPWTESLRREYVKLIDGFFSIPFPLACLLPFTTYGQALKARKKVAGALREVIKKRMEEKAENGGSIGDDEGKKEKKDMVEELLQAEGGSFSEEEMVDFCLSLLVAGYETTSVLMTLAVKFLTETPAALAELKEEHANIRDMKGKNQPLEWSDYKSMPFTQCVINETLRVGNIISGVFRRANTDIHYKDYTIPKGCKIFASFRAVHLNNEHYENARTFNPWRWQINNKLQNAVGANIFTPFGGGPRLCPGYELARVVVSIFLHHLVTRFSWEETEEDRLVFFPTTRTLKGYPINLRLLSESIC
What is the function of this protein?
Catalyzes the C23-alpha-hydroxylation step in brassinosteroid biosynthesis (By similarity).  Converts 6-deoxocathasterone to 6-deoxoteasterone in the late C6-oxidation pathway and cathasterone to teasterone (TE) in the early C6-oxidation pathway of brassinolide (BL) biosynthesis (By similarity).
What are the official names of this protein?
Cytochrome P450 90A4, OsCYP90A4.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: VLMB_LECSP
Sequence: MEVKKLEFIGPRVMPGGQKEMDYFCQVPEFQQRCQSGNAVVIPRRDQVADGRGSTGKLFSQTLNTADTIPHCIVMFEDTYTAQSSTQPWLPISTCSVFYQLGEGVCGFGNICHGGIQTTLLDDVMGVLGVLNARLQDGIIPSKVPGAYWPRNNPGMVDLTKSLFATQGIEVKFLRPLRTPQVIEVSAQLVDMDVSGGSFTVQCVIRDMKGKQYAVANANWVIHTPRPRSRL
What is the function of this protein?
Part of the gene cluster that mediates the biosynthesis of verlamelin, a lipopeptide that exhibits antifungal activity against plant pathogenic fungi (PubMed:24848421).  Verlamelin is a cyclic hexadepsipeptide and is bridged by ester bonding between a 5-hydroxytetradecanoic acid moiety and a carboxyl group on the terminal Val of amide-bonded tetradecanoyl-hexapeptide D-allo-Thr-D-Ala-L-Pro-L-Gln-D-Tyr-L-Val (PubMed:24848421).  VlmA and vlmB are altogether regarded as essential components in the biosynthesis of 5-hydroxytetradecanoic acid (PubMed:24848421).  VlmA catalyzes the hydroxylation at position C5 of tetradecanoic acid produced in primary metabolism, while the precise function of vlmB still remains to be solved (PubMed:24848421).  To be loaded onto the waiting NRPS, 5-hydroxytetradecanoic acid is activated in the form of acyladenylate by the AMP-dependent ligase vlmC (PubMed:24848421).  VlmS seems to accept the fatty-acyl intermediate onto the initial module to further elongate amino acid residues by the downstream modules (PubMed:24848421).  In addition, in the last module at its C-terminus, vlmS contains a surplus condensation (C) domain that may be involved in cyclization, the last step to form verlamelin (PubMed:24848421).
What are the official names of this protein?
Verlamelin biosynthesis protein B.