PharMolix/UniProtQA huggingface dataset:
Protein: MRAY_PROM9
Sequence: MIGKIKKFNFKSLLILNTFALIATSYLFNNFIFIGVYTLFFFISLFTTKNGIKIIKKLNLLQNIRTEGPANHLKKSDTPTMGGVFMVIPFLIFLLIININLGSLKLFLLLLTIFGFFITGFVDDFLSIKKEQNTGLKTKEKFFLQSIIAIIFIFLAYEKDLINPLITVSDSWQINMNIFTLPISFLVLVGISNSVNLTDGLDGLAAGCSGIVFYGLGTEILMKEQQELIIFSILCYSMSGICLGFLKYNSYPAKIFMGDTGSLSIGAILGSIALLTNSVFTLSIFSGIFIIESLSVMIQVGVFKITKKLFHNGKRIFLMAPLHHHFELKGVKEQKIVENFWKINILLVILGIVLKINL
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RM44_ASHGO
Sequence: MITKYFTKIFVRFNPFGPEAKTARLFLCAIPPRQRAISTKLTNELLTANSQKTPLIKVVFKDKTEMELDPAGLSFGELSSHLDRYSRKLQLKENIESQ
What is the function of this protein?
Component of the large subunit of mitochondrial ribosome.
What are the official names of this protein?
54S ribosomal protein L44, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mL53 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: H2A1B_HUMAN
Sequence: MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHHKAKGK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A type 1-B/E, Histone H2A.2, Histone H2A/a, Histone H2A/m.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: CLPX_STRMK
Sequence: MSEDRQGRSTDTGKILYCSFCGKSQHEVRKLIAGPSVFICDECVELCNDIIREELEEKAQSARSSLPKPREILEVLDQYVIGQNRAKRTLAVAVYNHYKRIESRQKNDDVELAKSNILLVGPTGSGKTLLAETLARLLNVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQQGIVYIDEIDKISRKSENPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVDTKNILFICGGAFAGLDKVIQARSTDVGSIGFGAKVKSSERKQEVGKVLAEVEPEDLIKFGLIPEFVGRLPVVATLEELDEPALIKILTEPKNAITKQFKKLFEMENVELEFRPDALSAIARKALKRKTGARGLRTIVESVLLDTMYDLPSQENVSKVVVDESVIEHKSEPYLIYQTPAAPEQKAAGAE
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: BAG5_HUMAN
Sequence: MDMGNQHPSISRLQEIQKEVKSVEQQVIGFSGLSDDKNYKKLERILTKQLFEIDSVDTEGKGDIQQARKRAAQETERLLKELEQNANHPHRIEIQNIFEEAQSLVREKIVPFYNGGNCVTDEFEEGIQDIILRLTHVKTGGKISLRKARYHTLTKICAVQEIIEDCMKKQPSLPLSEDAHPSVAKINFVMCEVNKARGVLIALLMGVNNNETCRHLSCVLSGLIADLDALDVCGRTEIRNYRREVVEDINKLLKYLDLEEEADTTKAFDLRQNHSILKIEKVLKRMREIKNELLQAQNPSELYLSSKTELQGLIGQLDEVSLEKNPCIREARRRAVIEVQTLITYIDLKEALEKRKLFACEEHPSHKAVWNVLGNLSEIQGEVLSFDGNRTDKNYIRLEELLTKQLLALDAVDPQGEEKCKAARKQAVRLAQNILSYLDLKSDEWEY
What is the function of this protein?
Co-chaperone for HSP/HSP70 proteins.  It functions as a nucleotide-exchange factor promoting the release of ADP from HSP70, thereby activating HSP70-mediated protein refolding (PubMed:20223214).  Has an essential role in maintaining proteostasis at junctional membrane complexes (JMC), where it may function as a scaffold between the HSPA8 chaperone and JMC proteins enabling correct, HSPA8-dependent JMC protein folding (By similarity).  Inhibits both auto-ubiquitination of PRKN and ubiquitination of target proteins by PRKN (By similarity).
What are the official names of this protein?
BAG family molecular chaperone regulator 5, BAG-5, Bcl-2-associated athanogene 5.
Protein: YBEY_XYLF2
Sequence: MTRGPIFLNVGISYGLPRTKLPAAVSFRKWVAATLQGRIRKADLAIRIVDEKEGRALNYHYRNKDYATNVLSFPAQLPEPFPKALKIPLLGDIVMCAPVIAREATEQGKSLSAHYAHLTVHGTLHLLGWNHEDHQEADAMEQLEREILANLGISDPYLGEY
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRDA_CLOB1
Sequence: MSLFEGKKVIIIGDRDGIPGPAIEKCIEGTGAEVVFSSTECFVUTAAGAMDLENQKRVKTLTEKHGAENILVILGAAEGEAAGLAAETVTNGDPTFAGPLSNVQLGLRVYHAVEPEFKEEVNEEVYEEEIGMMEMVLEVDEIIEEMTDIRTEFCKFLD
What is the function of this protein?
In the first step of glycine, betaine and sarcosine reductases, the substrate is bound to component PB via a Schiff base intermediate.  Then the PB-activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a carboxymethylated selenoether and the respective amine.  By action of component PC, acetyl phosphate is formed, leaving component PA in its oxidized state.  Finally component PA becomes reduced by the thioredoxin system to start a new catalytic cycle of reductive deamination.
What are the official names of this protein?
Glycine/sarcosine/betaine reductase complex component A, Selenoprotein PA, Thioredoxin reductase complex selenoprotein A.
What is the protein family that this protein belongs to?
Belongs to the GrdA family.
Protein: YUIB_LACLA
Sequence: MTFYNYLMRHRAPVEKDDATRLANLVFQDPLFPKQSKDFDEISTYLETQAPFYFNLTLFDNIWESYLEA
What are the official names of this protein?
UPF0346 protein YuiB.
What is the protein family that this protein belongs to?
Belongs to the UPF0346 family.
Protein: RL15E_METMP
Sequence: MSMYNYVKEAWKVPANSYVKELQWARMQDWRKEPSVLRIERPTRIDRARNLGYKAKQGIVVVRVSVRRGGLRKPRPKHSKKPATLGINKITMAKSIQRIAEERAAKRYPNMEVLNSYWVGQDGKQKWYEIILVDPCHPSIKNDKSYSWLSTGNHKGRANRGLTSAGKKGRGLMYKGKGAEKARPGVRANGKKTK
What are the official names of this protein?
50S ribosomal protein L15e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL15 family.
Protein: ECFA1_STAHJ
Sequence: MEANNTNIIELKQVDFQYQGDAAFTLNNVSFKIPKNQWTSIVGHNGSGKSTIAKLIVGIEIATNGTIIFNQSPISNNDFKDIREHVGIVFQNPENQFVGSIVKYDVAFGLENHAVPTEKMKEIVAQSISDVGMTDYADSEPHSLSGGQKQRVAIAGVLALSPSVIILDEATSMLDPQAKKSLMSLIQEVKATKDVTIISITHDLTEALEGDHVIVMNQGTVYKEGNPQTIFKDIKMLQEIGLDLPFSMKINQLLGFDDHFITYEGLVEKL
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA1, ECF transporter A component EcfA1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GKN1_HUMAN
Sequence: MKFTIVFAGLLGVFLAPALANYNINVNDDNNNAGSGQQSVSVNNEHNVANVDNNNGWDSWNSIWDYGNGFAATRLFQKKTCIVHKMNKEVMPSIQSLDALVKEKKLQGKGPGGPPPKGLMYSVNPNKVDDLSKFGKNIANMCRGIPTYMAEEMQEASLFFYSGTCYTTSVLWIVDISFCGDTVEN
What is the function of this protein?
Has mitogenic activity and may be involved in maintaining the integrity of the gastric mucosal epithelium.
What are the official names of this protein?
Gastrokine-1, 18 kDa antrum mucosa protein, AMP-18, Protein CA11.
What is the protein family that this protein belongs to?
Belongs to the gastrokine family.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic granule. Golgi apparatus. Note=Shows abundant granular cytoplasmic staining, with perinuclear accentuation suggestive of the Golgi apparatus.
Protein: TBP_ACACA
Sequence: MSGITLPSLTNVLQSAGMAVHGHPSAPGSTQLPPLHQLNISSQPSSQPPQPSLQYSEPAQSTAASDDMDSDVDRTKHPSGIVPTLQNIVSTVNLGCKLDLKNIALHARNAEYNPKRFAAVIMRIREPKTTALIFASGKMVCTGAKSEEASRLAARKYARIIQKLGFAAKFLDFKIQNIVGSCDVRFPIRLEGLAFAHNHYCSYEPELFPGLIYRMVQPKIVLLIFVSGKIVLTGAKVREEIYEAFENIYPVLTEYKKT
What is the function of this protein?
General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID.  Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II.
What are the official names of this protein?
TATA-box-binding protein, TATA sequence-binding protein, TBP, TATA-binding factor, TATA-box factor, Transcription initiation factor TFIID TBP subunit.
What is the protein family that this protein belongs to?
Belongs to the TBP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CUCN_CUCMA
Sequence: PQRGEGGRAGNLLREEQEI
What is the function of this protein?
Has antifungal activity against B. cinerea, F. oxysporum and M. arachidicola.  Inhibits cell-free translation in rabbit reticulocyte lysate system.
What are the official names of this protein?
Cucurmoschin.
Protein: ISPE_XANAC
Sequence: MDRIALMDAPDTDWSAWPAPAKLNLFLQITGRRADGYHLLQTVFRLLDWGDTVHLRVRSGGQIRRVGESLPGVAEDDDLVIRAARLLQSATGAQAGAEIRVDKRIPAGGGFGGGSSDAATVLVALNALWGLGLAADALAELGLQLGADVPVFVRGHNAWAEGVGEQLTPISLPEAAYLLVDPGVHVPTPALFRSQELTRDAAPAKIADFASGSLLDNAFEPVLRRREPAVEAVFQALSRVGTPRLTGSGSGCFVEFATRAAAEQALAQLPGGLRAWVAEGASHSPLLDARDARQV
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: Y2042_SYNY3
Sequence: MLPTAIVLTILLGIIAYIWGYPHWLDWREKQLFQRPLPPHWQAILGDRLPFYAQLSPQQRQKLEAKIQLFLQQKQFIGCNDFVLTDEVRLVIAAQACYLALELGSNPYPRLDTILVYPDAFQVRQITSPDGYVVEEEDTVRAGESWDRAGQLILAWGTIAWDLERWQDGHNVIFHEFAHQLDMGDGAMNGVPKLGRRNDYQRWQSIFASEYQQLLSQLENNLPTVIDPYGATNPCEFFAVVTETFFEKGQELQHNHGQLYQVLRKYYCLEPLINC
What are the official names of this protein?
Uncharacterized protein slr2042.
What is the protein family that this protein belongs to?
Belongs to the MtfA family.
Protein: AIS_SALPK
Sequence: MLAFTLRFIKNKRYLATLAGALVIIAGLTSQHAWSGNGLPQINGKALAALAKQHPVVVLFRHAERCDRSDNTCLSDSTGITVNGAQDARALGKAFSADIQNYNLYSSNTVRTIQSATWFSAGRSFTVDKKMMDCGSGIYASINTLLKKSQNKNIVIFTHNHCLTYIAKNKRGVKFDPDYLNALVMHAENGKLFLDGEFVPG
What is the function of this protein?
Catalyzes the dephosphorylation of heptose(II) of the outer membrane lipopolysaccharide core.
What are the official names of this protein?
Lipopolysaccharide core heptose(II)-phosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. Ais subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: CLPB_CHLCV
Sequence: MDKISDAVSEALEKAFELAQSAKNPYVSENHFLKCLLENTESLFYLIIKDIHNNPKLLTSAVDEALSLEPSVIEGSAMPKPSPGLQSLLLDAKQEAKDLGDEYLSGDHVLLAFWKSNKEPFASWKKTVKISLDDLKKLIINIRRGNRMDSPSAENNLRGLEKYCKNLTLLAKEGKLDPVIGRDEEIRRTVQVLSRRTKNNPMLIGEPGVGKTAIAEGLALRIVQGDIPESLKGKQLYVLDMGALIAGAKYRGEFEERLKSVLKDVESVDGESILFIDEVHTLVGAGATDGAMDAANLLKPALARGTLHCIGATTLNEYQKYIEKDAALERRFQPIFVTEPSLEDAVFILRGLREKYEIFHGVRITEGALNAAVLLSYRYIPDRFLPDKAIDLIDEAASLIRMQIGSLPLPIDEKERELAALIVKQEAIKREKAPSYQEEAAAMQQSIEQLKEELAALRLRWDEEKKLITGLKEKKNSLENMKFSEEEAERVADYNRVAELRYSLIPALEEEIREDEEALNQRDNRLLQEEVDERLIAQVVANWTGIPIQKMLEGEAEKLLVLEESLEERVVGQPFAISAVSDSIRAARVGLSDPQRPLGVFLFLGPTGVGKTELAKALADLLFNKEEAMVRFDMTEYMEKHSVSKLIGSPPGYVGYEEGGSLSEALRRRPYSVVLFDEIEKADKEVFNILLQIFDEGILTDSKKRKVNCKNALFIMTSNIGSQELADYCAKKGSRVSKETVLSVVAPTLKKYFSPEFINRIDDILPFVPLNTEDIVKIVGIQMRRVAQRLLERRVTLTWDDSVILYLSEQGYDSSFGARPLKRLIQQKVVTLLSKALLKGDIKSDTSIELTMSKDVLLFKKIEG
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GFA_VERA1
Sequence: MSFPLHPSLVNGITKGNPSFQGGVLKCKCSTSPVTVTLRSNVAHNHACGCSKCWKPEGALFSIVSVVPVDKLEVTANGDKLAVVDPSATILRHACTGCGVHLYGRIEKDHAFKGLDFVHTELSDEKGWQEPQFAGFVTSIIEQGFDARHIDDVRAQFESLGLESYDALNPPLMNAIAAFTAANEAKA
What is the function of this protein?
Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione.
What are the official names of this protein?
Putative glutathione-dependent formaldehyde-activating enzyme, S-(hydroxymethyl)glutathione synthase.
What is the protein family that this protein belongs to?
Belongs to the Gfa family.
Protein: MNHG2_STAAB
Sequence: MEITKEIFSLIAAVMLLLGSFIALISAIGIVKFQDVFLRSHAATKSSTLSVLLTLIGVLIYFIVNTGFFSVRLLLSLVFINLTSPVGMHLVARAAYRNGAYMYRKNDDHTHASILLSSNEQNSTEALQLRAKKREEHRKKWYQND
What are the official names of this protein?
Putative antiporter subunit mnhG2, Mrp complex subunit G2, Putative NADH-ubiquinone oxidoreductase subunit mnhF2.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYV_MESH7
Sequence: MKNKYDFKLVEEKRNEKWQKKGFFIAPKQTKKPFSIISPPPNVTGQLHLGHSWNAFIQDSLVRYHKLQGFDVLLLPSVDHAGIATQVKVEEDLAKKGIKKSDLKREEFIKKCYHWKEKQYLKIKEQWDKLGICYDFSKERFTLDQDAQIAVSDFFIKLWEKNLIYRGQKAINWDIKLQTAISNIEVINKPVEQKMYYLKYFLENSNEFLTVATTRIETISSDVALAINPKDKRYLHLVGKKVVHPLTKKLIIIIADSNVSSDFGSGIMKVSAHSILDFEIMEKHNLESKDCIDNYGNLNHEVPEFQGQNRFFARDLIAKKLEKEGFLAKIETVISNVGFSQRSDEIVEILKKPQWFVKMDELAKSLISHLNSKDKIKFYPKNFEKNLRKWFEKIHDWTISRQLWWGHRIPVWCKNDEFKVQIDSPGQGWIQDEDVLDTWFSSGISAFAFLGWPQNFDLIKSYFPTSLLVTGWDILFFWVARMYFSSLFIMKQKPFEKVLLHGLIRDEIGRKMSKSLGNGLDPMEIIEKYGSDTLRQALIFNSSPGKDIKFNIEKLNTAWNLNNKIWNIAKYIADLDTFFAKPDLIDLWMENKIYILKRQIVKNIKKYNFSVIGTEINNFIYGDFSSRYIELIKTRKNGFYARKLLRKVLIILHPFLPFLTDFLMEKIFKMEILEQKMPRIRQFKENQKVENILEIIDNLRTYREKFQISKKIILEYCIINDKFSNAEIDIINKLTFGKWLENKELVIKTKNFEIAIKVPEELKKEQKGRELKEIQFLKSEILRAEKILTNKGFLEKAPREKIDLERTKLEKLKEKLAFYEKK
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HNRH2_PONAB
Sequence: MMLSTEGREGFVVKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPSGEAFVELESEEEVKLALKKDRETMGHRYVEVFKSNSVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGRGYNSIGRGAGFERMRRGAYGGGYGGYDDYGGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGSSFQSTTGHCVHMRGLPYRATENDIYNFFSPLNPMRVHIEIGPDGRVTGEADVEFATHEDAVAAMAKDKANMQHRYVELFLNSTAGTSGGAYDHSYVELFLNSTAGASGGAYGSQMMGGMGLSNQSSYGGPASQQLSGGYGGGYGGQSSMSGYDQVLQENSSDYQSNLA
What is the function of this protein?
This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm.  Binds poly(RG) (By similarity).
What are the official names of this protein?
Heterogeneous nuclear ribonucleoprotein H2, hnRNP H2, Heterogeneous nuclear ribonucleoprotein H', hnRNP H'.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm.
Protein: BLM_XENLA
Sequence: MAALPQNNLQKQLELFPAKGTSNKLSLQKTKSSVFTFKKKCSPNVSASTGFIPFQQHVLKDKNVNVKQDGTHTALPKATERNKINCFFTPVYTKSGQPPQVVALKDHVHGNDSANKPPSTEDAASKKTGINTSFGSVTSLEEWDDLDDFDTSVSPPKSHAGKGGKTPQKCKNTSPVASFKIQSISPEGPTTEKHDCAKLLYDNNEVASEPRKNLHAKTAESPDQSLVCLASVEPTNLERDMCRNTDYLGTDDLEHDQETLSQVLIEEEDDCEPDFIPPSPSDESLSSPPVLKVISAQRKHKVSSLTDVNDCENTTDHLQGQSVSTSLDSKVPSQLLTLMLEICDLVDKIPISELHVLSCGLDLKKKRDMRKRLLSNDSVFRSSPADSSTVSLTSCTSSTQNRDFNVNAPKGAESLSGSSVSKVFKFNKLAVHDIGTKESENSANSAPNFMEKIGNKTSFSFRAGGDSIMENSFNFHSSVLSNSRFNTPQNEKPISSSTCTRPYSQPIDDMDNPDLDFDIDNFDIEDLDDIHCLDSPAAPSVSSKNVPQYPTIREAQLDSRNKEKNTRNNTGDTTNPSLLSDSLLKPQIENPAHERFRGFNFPHSKEMMKIFHKKFGLHRFRTNQLEAINACLCGEDCFILMPTGGGKSLCYQLPGCISPGVTIVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDAEAASIYLQLSKKDPIIKLLYVTPEKVCASTRLISTMENLYERQLLARFVIDEAHCVSQWGHDFRPDYKRLNVLRQKFQSVPMMALTATANPRVKKDILNQLKMTKPQIFTMSFNRDNLKYEVLPKKPKRVALDCVEWIKKHHPNDSGIIYCLSRHECDTMADTLQKEGLAALAYHAGLADSNRDYVQHKWINQDDCQVICATIAFGMGIDKPDVRYVIHASLPKSVEGYYQESGRAGRDGETSHCLLFYSYHDVTRIRRLIQMEKDGNSHTKQTHFNNLYSMVHYCENVVECRRMQLLSYFGENNFNPNFCKEHTQVACDNCLGKKNYKSRDVTDDVGNIVRFVQDNCSLVQGRGKGRSNNTRLTLNMMVDIFLGSKSAKIQTGLFGKGAAYSRHNAERLFRKLVLDRIIDEELYITFNDQAVAYVKMGERAQAVLNGFLKVDFQDTESASSIRKQKASVVTNTSQREEMVKKCQAELTELCKRLGKIFGVHYFNIFNTATIRRIAESLSPEPEVLLQIDGVTEDKLDKYGAELIDVLQKYSEWTLPVEDICQKSGGPANVSARRSNSDHDDESCDKSSYFSSNNKKGPKRKNSSYFGKSKKRKTGGDGQQSRSKNGNSSYARKNSTAKTSSSYISGSKTGADKRPGFMAPPMPQPNRRFLKPSYSMF
What is the function of this protein?
ATP-dependent DNA helicase that unwinds single- and double-stranded DNA in a 3'-5' direction.  Participates in DNA replication and repair (PubMed:11040210).  Involved in 5'-end resection of DNA during double-strand break (DSB) repair.  Negatively regulates sister chromatid exchange (SCE).  Stimulates DNA 4-way junction branch migration and DNA Holliday junction dissolution.  Binds single-stranded DNA (ssDNA), forked duplex DNA and DNA Holliday junction.
What are the official names of this protein?
RecQ-like DNA helicase BLM, Bloom syndrome protein homolog, xBLM, RecQ helicase homolog.
What is the protein family that this protein belongs to?
Belongs to the helicase family. RecQ subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: KAPC_ASPNC
Sequence: MQPTLAPAPHPSMQTSAQDHADQVLHDQLLAAHQHLSHPQQARPQGPTAQPPHMQPNTTSPRDQNNIDPAISGAAMLSGPPQTPPQPEPTGQESPKTYGKRPLSTSKRAAQNRAAQRAFRQRKESYIRKLEEQVKEFDNTNETMKQLQAENYQLREYIINLQSRLLDSQGEVPELPGNIDLNQPRNDISVPPPGAPAATGPAPGPGGAPQQMQVPNPGAATNEDMNSLNRIAVAGLGMRKHPNEEANFLGNNFQARRPRNDDGQPDGSEATKTEPGHGLPVVS
What is the function of this protein?
Putative transcription factor.
What are the official names of this protein?
Putative transcription factor kapC.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RAB26_RAT
Sequence: MSRKKTPKSKGGSVPAASTLPAAANGPRLAHPRTARPGPEAPPNGPPQSGRPSLGGTGDFYDVAFKVMLVGDSGVGKTCLLVRFKDGAFLAGTFISTVGIDFRNKVLDVDGMKVKLQIWDTAGQERFRSVTHAYYRDAHALLLLYDITNKDSFDNIQAWLTEIQEYAQQDVVLMLLGNKVDSTQERVVKREDGEKLAKEYGLPFMETSAKSGLNVDLAFTAIAKELKQRSTKAPSEPRFRLHDYVKREGRGVSCCRL
What is the function of this protein?
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes.  Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion.  Mediates transport of ADRA2A and ADRA2B from the Golgi to the cell membrane.  Plays a role in the maturation of zymogenic granules and in pepsinogen secretion in the stomach (By similarity).  Plays a role in the secretion of amylase from acinar granules in the parotid gland.
What are the official names of this protein?
Ras-related protein Rab-26.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle membrane; Lipid- anchor; Cytoplasmic side. Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side. Note=Inhibition of S-geranylgeranyl cysteine formation abolishes membrane location (By similarity). Localized immediately around secretory granules in the acinar cells of the parotid gland (PubMed:10857477). Not localized in plasma membranes (PubMed:10857477).
Protein: PDXS_TROW8
Sequence: MGLDNLKVGLAQMLKGGVIMDVVTPDQAKIAEDAGAVAVMALEKIPSDIRASGGVSRMSDPGLIERVMDSVSIPVMAKVRIGHFAEAQILQSLKVDYIDESEVLSVADSSYHIDKRKFTVPFVCGATNLGEALRRISEGASMIRSKGEAGTGDIAQATKHIRAILSEISALTQAREDELPARARELGAPIDLVRETARLGRLPVVLFTAGGIATPADSSLVMQLGSDGVFVGSGIFKSEDPKAYAAAIVQATAQYDDADLLARVSRNLGQAMPGVSNLDVRFSSRGV
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: NS1A_HASV4
Sequence: MAHGEPYYSSKPDKDFNFGSTMARRQMTPTMVAKLPNFVRNSPQAYDWIVRGLIFPTTGKTYFQRVVVITGGLEDGTYGSFVFDGREWVEIYPIEHLNLMSSLKLIHKANALQERLRLSQEEKATLALDVQFLQHENVRLKELIPKPEPRKIQMKWIIVGAVLTFLSLIPGGYAQSQINNTIFTDMIAACKYSTETLTENLDLRIKLALANITISDKLDAVRQILNFAFVPRAHWLRTVFYYIHYYEMWNIFMFVLAIGTVMRSARPGTDLITLATSHLSGFRMAVLPTIPFHTTMTLWVMNTLMVCYYFDNLLAITLAILAPILGIIFLCFMEDSNYVSQIRGLIATAVLIAGGHACLTLTGTTTSLFVVILTCRFIRMATVFIGTRFEIRDANGKVVATVPTRIKNVAFDFFQKLKQSGVRVGVNEFVVIKPGALCVIDTPEGKGTGFFSGNDIVTAAHAVGNNTFVNVCYEGLMYEAKVRYMPEKDIAFITCPGDLHPTARLKLSKNPDYSCVTVMAYVNEDLVVSTAAAMVHGNTLSYAVRTQDGMSGAPVCDKYGRVLAVHQTNTGYTGGAVIIDPTDFHPVKAPSRVELLKEEIERLKAQLNSAAENPATAVTQQPVVTLEQKSVSDSDVVDLVRTAMEREMKVLRDEINGILAPFLQKKKGKTKHGRGRVRRNLRKGVKLLTEEEYRELLEKGLDRETFLDLIDRIIGERSGYPDYDDEDYYDEDDDGWGVVGDDVEFDYTEVINFDQAKPTPAPRTVKPKTCPEPEAETQPLDLSQKKEKQLEHEQQVVKSTKPQKNEPQPYSQTYGKAPIWESYDFDWDEDDAKFILPAPHRLTKADEIVLGSKIVKLRTIIETAIKTQNYSALPEAVFELDKAAYEAGLEGFLQRVKSKNKAPKNYKGPQKTKGPKTITH
What is the function of this protein?
Protein covalently attached to the 5' extremity of the genomic and subgenomic RNAs.
What are the official names of this protein?
Non-structural polyprotein 1A.
What is the protein family that this protein belongs to?
Belongs to the astroviridae polyprotein 1A family.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.