PharMolix/UniProtQA huggingface dataset:
Protein: HMOX1_PONAB
Sequence: MERPQPDSMPQDLSEALKEATKEVHTQAENAEFMRNFQKGQVTREGFKLVMASLYHIYVALEEEIEHNKESPVFAPVYFPEELHRKAALEQDLAFWYGPRWQEVIPYTPAMQRYVKRLHEVGRTEPELLVAHAYTRYLGDLSGGQVLKKIAQKALGLPSSGEGLAFFTFPNIASATKFKQLYRSRMNSLEMTPAVRQRVIEEAKTAFLLNIQLFEELQELLTHDTKDQSPSRAPGLRQRASNKAQDSAPVETPRGKTPLNTHSQAPLLRWVLTLSFLVATVAVGLYAM
What is the function of this protein?
Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron.
What are the official names of this protein?
Heme oxygenase 1, HO-1.
What is the protein family that this protein belongs to?
Belongs to the heme oxygenase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type IV membrane protein; Cytoplasmic side.
Protein: ECFA2_MYCCT
Sequence: MDFSKDIILDNVSYTYAKKTPFEFKALNNTSLKFKKNKVTCVIGTTGSGKSTMIQLTNGLIITETGQTIVGDYAIPANIKKIKEVKRLRKEIGLVFQFPEYQLFQETIEKDIAFGPVNLGENKQEAYKKVPELLKLVQLPEDYVKRSPFELSGGQKRRVALAGIIAMDGNTLVLDEPTGGLDPKGEEDFINLFERLNKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVIDIGSPFEIFSNIELLTKIEIDPPKLYQLMYKLKNKGIDLLNKNIRTIEEFASELAKVLK
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA2, ECF transporter A component EcfA2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: EXU_DROVI
Sequence: MVAVSIDSVIDISAADQSTAASGVAIKDELPNGDYILVAVDIDTTGRRLIDEIVQLAAYTPTDHFEQYIMPYMNLNPAARQRHQVRVISIGFFRMLKSMQTYKIIKSKSEVAALKDFLDWLDQLKSKNPNTDGIVLLYHEERKFIPYMILQSLVKYGMLDRFTKTVKSFVNSFNLAKSSIGDTKHYSLRNLSKILSKAKEDNARVDNDNEADSNSSSADKHVKNGLQKERDEFDGSASVRAKLTFNVALQLSNLDSTEPESSEALSNLFNALKPFTEAISGDVKELDTQNVHLERQNSFRPVFLNYFKTTLYHRVRAVKFRIVLAENGFDLTTLNDIWTEKRIEGLDAALQGIASLKAEDKNELVELLDSFFDPAKVTIKPIIKPSTIRRRNKRNTPAHKPGVGSGSRSASDEFGAGGDKSQSVSSVPDSTTKTPSPIKNGGRPQRKRNSRPSLHTKEVKSAESALNNTAPASISLPNYVPIAATN
What is the function of this protein?
Ensures the proper localization of the mRNA of the bicoid gene to the anterior regions of the oocyte thus playing a fundamental role in the establishment of the polarity of the oocyte.  May bind the bcd mRNA (By similarity).
What are the official names of this protein?
Maternal protein exuperantia.
Protein: ARGR_ANASK
Sequence: MTSADRRRDAVARIIRARRIGTQEELLAALERAGFRATQATLSRDLARLGARRVSGPEGAVYELGADGADGGLAALRGLVSSIAANASMVVIRTHPGSAPAIARAIDLAQPPEVLGTIAGDDTIFVAPAGELRPRRLAARLAELLGTPSALAGDGGERTH
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA_GEOKA
Sequence: MENIAVLGAGSWGTALALVLADNGHHVRLWGHRTEQISEINEKRTNEKYLPGVRLPDAIIGYDDLCAALDGVAIVVLAVPTKAIRSVLADVRACLAKPITIVAVSKGIEPGTHKRVSEMVAEEMGEWLADVVVLSGPSHAEEVVLRHPTTVAVSSPNMEAARRIQDIFMNHHYFRVYTNPDLIGVEVGGALKNIIALAAGISDGLGYGDNAKAALITRGLAEIARLGCALGANPLTFAGLTGVGDLIVTCTSVHSRNWRAGYMLGQGKKLDEVLESMGMVVEGVRTTKAAYELAKELGVKMPITEALYDVLFAGKDPKEAVDSLMARGKKEEMDDLNNIFAEQE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPF_LISM4
Sequence: MLKYNIRGENIEVTEPIRDYVEKKIDKLERYFTETPDANVHVNLKVYSDKNAKVEVTIPLPNLVLRAEETSGDLYASIDLIVDKLERQIRKHKTKVNRKFRDKGAERDYFAYSDVNGSTPPEENEGDFDLEIVRTKQFSLKPMDSEEAVLQMNLLGHSFYVYTDAETNGTNIVYSRKDGKYGLIETN
What is the function of this protein?
Involved in 100S ribosome formation from 70S ribosomes; 100S ribosomes are probably translationally inactive (PubMed:25422304).  Ribosome hibernation may be used by the cell to decrease overall energy consumption under nutrient-limiting conditions (PubMed:26324267).  Unlike E. coli, 100S ribosomes are present from mid-exponential growth, peak during the transition from log to stationary phase and then decrease (PubMed:25422304).
What are the official names of this protein?
Ribosome hibernation promotion factor, HPF, Ribosome hibernation-promoting factor.
What is the protein family that this protein belongs to?
Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MASU1_MOUSE
Sequence: MGPGWSPARRLWPLLWRRAVFQRAGPAMASVPWLPRLAERWLPARPATCLTPSLTRGLHHGPQPEERTAGDARLQPGPADHIGAKFDIDMLVSLLRQENARDICVIQVPPEMRYTDYFVIGSGTSTRHLHAMVHYLVKMYKHLKCRSDPYVKIEGKDADDWLCVDFGSMVIHLMLPETRETYELEKLWTLRSFDDQLAQIAAETLPEDFILGLEDDTSSLTPVEFKCK
What is the function of this protein?
Required for normal mitochondrial ribosome function and mitochondrial translation.  May play a role in ribosome biogenesis by preventing premature association of the 28S and 39S ribosomal subunits.  Interacts with mitochondrial ribosomal protein L14 (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits.  Addition to isolated mitochondrial ribosomal subunits partially inhibits translation, probably by interfering with the association of the 28S and 39S ribosomal subunits and the formation of functional ribosomes.  May also participate in the assembly and/or regulation of the stability of the large subunit of the mitochondrial ribosome.  May function as a ribosomal silencing factor.
What are the official names of this protein?
Mitochondrial assembly of ribosomal large subunit protein 1.
What is the protein family that this protein belongs to?
Belongs to the Iojap/RsfS family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Note=Colocalizes with MRPL12 and/or MRPL14.
Protein: KEX1_VERA1
Sequence: MAPAIRQLATGLLLALSWAPTTRADSSAADYYVKSLPGQPAGPPVKMHAGHIETDADHNGNLFFWHFENKHIAQRQRTVIWLNGGPGCSSEDGAMMEIGPYRVKGDQLVNNNGSWHEFANLLFVDNPVGTGFSYVDTNSYLHELDEMGDQFILFLEKFFKLFPQYAQDDLYFAGESYAGQHIPYIAKHILERNEKAGPDDQWNLKGLVIGNGWISPFEQYGSYLKFAYEKGLLAQGSEKAKQLEQQWKICRKQMAVDIKIDISECEAILQKILDVTATLTTSGKRNCYNMYDVRLKDTYPSCGMNWPPDLTDVTPYLRRKDVTEALHINAAKNTGWKECNGAVGSAFRAHKSKPSRDLLPDLLKKVPITLFSGAEDLICNHIGTEEMIGNMEWNGAKGFEVSPGNWAPRRDWTFEGKDAGFWQEARNLTYVLFKEASHMVPFDWPRRSRDMIDRVMKVDISAIGGEPTDSRIDGEKGPVTSVPPSKGSNNHPDTKPGGGDKGSSTNDDETQKQVDEAKWKAYYRSGEIVLVIVVIAAGLWGWYIWRDRRRRSGYQGVAGGDGAGPGHRAGARGLDRFQDRRTARDVETGDFDESELDDLHVETPREGPHKEAYAIGDDSDEEDIKGKGPERSGTR
What is the function of this protein?
Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors.  Promotes cell fusion and is involved in the programmed cell death (By similarity).
What are the official names of this protein?
Pheromone-processing carboxypeptidase KEX1, Carboxypeptidase D.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein.
Protein: ISPD_CHLFF
Sequence: MNPKCSLILLSGGKGERFGANQPKQYLPFQGQPLILHALNSALLIPEINEIIVVCDASYEHIFEGYSVKFAPAGMRRQDSVFSGLHHVTNPWVLVHDGVRPFIYPDEVSELIVIAQQTGAATLVSNVPYTIKQRNPVKTLDRDSLSIVHTPQCIKTEILLEGLELADREQITLVDDTQAAELLGIPVSLVSNKHPQIKITYPEDLTIAHALL
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: PYRG_FRATH
Sequence: MNSNTKIIFVTGGVVSSLGKGVTAASLATLLESRGLNVTMMKLDPYINVDPGTMSPLQHGEVFVTEDGAETDLDLGHYERFIRNKMTQANNFTTGKVYQSVLRRERKGDYLGATIQVIPHITDEIKRRICSGIADDVDVAIVEIGGTVGDIESQPFLEAIRQLRIELGRNRTLFVHLTLLPYIKVAGEIKTKPTQHSVKELRGIGIQADVLVCRCEKKFDDSEKRKIALFTNVDQDCIFTAEDVDTIYEVPLKYNQQGFDAKLVELLNLNAKEADLSEWQNVVNTIRDVKGEVIIAMVGKYVSLTEAYKSLNEALYNAGYKKGVKVKIKFVDSEDVNENNVESYFKDVAAILVPGGFGSRGVEGKIISIKYARENQIPFLGICLGMQLAVIEYARNILGIKDAHSSELEPTTANPVIGLITEWQAEDGTVHQRTHSSDLGGTMRLGGYKCVLKQGSRAREIYQADEVVERHRHRYEVNSNYVERLEEAGLIFSGRSEDNKLMELIEIPQHKWFIACQAHPEFTSTPRYGHKLFESYIQAAIENSNN
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: MNME_CALS8
Sequence: MEFDTIAAISTPIGTGGIGIIRISGQNSIEVAGKIIKSKRFNSIYDIPVRYAALVEVYDNDEFIDQAILIKFKAPHSYTGEDVVEIQSHGGMVVLRRILEVVIKNGARHAMPGEFTKRAFLNGRLDLSQAEAIIDIINSKTELLQKNAAKQLKGVLSKKIDEIAEILLNLISSIEASIDFSEHEVDEISPQEIEKSIDTALEMIYRLLKTYETGRAIKSGIYTVIVGRPNVGKSSLLNRLLKEERSIVTDIPGTTRDVIEEVLDIEGIPIILVDTAGVRQTEDIVERIGVERTLKSVERADLVIFMIESDGITKEDIEIFSSIKNKKYIILVNKTDKGINISQDEIKKLFGKEGIFISIAKDENLELVEKAIKEAILEQNIEGFDEVLITNLRHKELLLKAKGFLTSAKQNLYSFPLDILSIDLKNALDSIYQITGKNVTEDMVDRIFSMFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADD_STAAW
Sequence: MKKIVLYGGQFNPIHTAHMIVASEVFHELQPDEFYFLPSFMSPLKKHNNFIDVQHRLTMIQMIIDELGFGDICDDEIKRGGQSYTYDTIKAFKEQHKDSELYFVIGTDQYNQLEKWYQIEYLKEMVTFVVVNRDKNSQNVENAMIAIQIPRVDISSTMIRQRVSEGKSIQVLVPKSVENYIKGEGLYEH
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: MURI_MYCTU
Sequence: MNSPLAPVGVFDSGVGGLTVARAIIDQLPDEDIVYVGDTGNGPYGPLTIPEIRAHALAIGDDLVGRGVKALVIACNSASSACLRDARERYQVPVVEVILPAVRRAVAATRNGRIGVIGTRATITSHAYQDAFAAARDTEITAVACPRFVDFVERGVTSGRQVLGLAQGYLEPLQRAEVDTLVLGCTHYPLLSGLIQLAMGENVTLVSSAEETAKEVVRVLTEIDLLRPHDAPPATRIFEATGDPEAFTKLAARFLGPVLGGVQPVHPSRIH
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: SYC_HALH5
Sequence: MAIQVFNSLTRKKEPFVPLEEGKVKMYVCGPTVYNYIHIGNARPPIVYDMIRRYLKYRGYEVLFVSNFTDVDDKIIRVANELGEDVFAVANRFIEAYKQDTSALGVLEADHHPRVTETMSEIISFIRVLEEKGYAYEQGGDVYFRTRKFKEYGKLSAQSIDDLLSGARIEVDERKEDPLDFVLWKAAKEGEVSWDSPWGKGRPGWHIECSAMVKKYLGDTIDIHAGGQDLKFPHHENEIAQSECMTGKPMANYWLHNGFINLDNEKMSKSLGNVVLANEMIRQHSAEVLRFFMLSAHYRSPINFSDELLEGAKRGLERLQTAVSSLVHRLQESADFGGTEPWLERIDEFRGRFIEEMDDDFNSANGIAVLFDLAKEANRYLREEQTSKAVLQSFIDLFNELGGVLGVTLNRQEELLDEEIERLIEERNEARKAKNFQRADDIRDQLKAEGIILEDTPQGVRWKRGS
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
Protein: 3MGH_STAES
Sequence: MIYLDFINQQTTQTAKALLGVKIIYQDDYQTYTGYIVETEAYLGIQDKAAHGFGGKITPKVTSLYKKGGTIYAHVMHTHLLINFVTRTEGIPEGVLIRAIEPDEGIGAMNVNRGKSGYELTNGPGKWTKAFNIPRSIDGSTLNDCKLSIDTNHRKYPKTIIESGRIGIPNKGEWTNKPLRFTVKGNPYVSRMRKSDFQNPDDTWK
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: TYSY_AZOVD
Sequence: MKQYLDLMRLVREHGTFKSDRTGTGTFSVFGHQMRFDLAEGFPLVTTKKCHLKSIVHELLWFLKGDTNIRYLKENGVSIWDEWADGNGDLGPVYGYQWRSWPAPDGRHIDQIANVVNMIRDNPDSRRLIVSAWNPALIDEMKLPPCHALFQFYVADGRLSCQLYQRSADIFLGVPFNIASYALLILMMAQVTGLAPGEFVWTGGDCHLYANHLEQADLQLSREPLPLPTMQLDPDVKDLFAFRFEDFELVGYQSHPHIKAPVAI
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_BDEBA
Sequence: MSTTKLDSIKDNALAAFKAAPSSKDLYDLKVQYLGKSGSLTEIMKEMASLPKEEKPLFGKKVNEVKQLLEAAYTEAEDALKKKEISAKMAAEEIDMTLPAFSQPKGTAHPVNIVVEEIFTVMSRLGYSIRTGPMIEKDYYNFEALNIPADHPARDMADTFFVDKTHVLRTHTSPIQIHSLENEELPLRVIGTGPVFRCDSDISHLPNFHQIEALCVDEKISMADLKGTISFFVREFFGPGLKTRFRPSYFPFTEPSAEVDCSCPICKGKGCSLCKQSGWIEIGGCGLVNPKVFQAAKIEYPKWQGFAFGFGVERMAIIKYGIEDIRLFPENDVRFLRQFVK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MQO_BACCQ
Sequence: MSNMQQKTDVILIGAGIMSATLGSLLKELAPEWEIKVFEKLASAGEESSNEWNNAGTGHSALCELNYTSEKSDGSIDISKAVKVNEQFQLSRQFWAYLVKSKLIRNPQDFIMPLPHMSLVQGEKNVQFLKNRFEALSKNPLFQGMEFSDSPETLKKWLPLIMEGRTSNEPMAATKIDSGTDVNFGALTRMLFDYLKTKNVELNYKHSVENIKRTKNGLWEVKVHDMNSGKIEHHTAKFVFIGGGGGSLPLLQKTGIPESKHIGGFPVSGLFMVCKNQKVVEQHHAKVYGKAKVGAPPMSVPHLDTRYIDNKKALLFGPFAGFSPKFLKTGSNLDLIGSVKPNNVLTMLAAGVKEMGLTKYLIQQVMLSHEKRMEELREFIPNAKSEDWDIVVAGQRVQVIKDTDAGGKGTLQFGTEVVSAADGSIAALLGASPGASTAVHVMLEVLEKCFPSRMVEWEGKIKEMIPSYGISLTENPRLFQDLHTSTGRTLGLNEKETVHN
What are the official names of this protein?
Probable malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: RL34_CARHZ
Sequence: MKRTYQPKNRRRKRVHGFLKRMRTPGGRNVIKRRRLKGRKRLTA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: GUC1B_BOVIN
Sequence: MGQQFSWEEAEENGAVGAADAAQLQEWYKKFLEECPSGTLFMHEFKRFFKVPDNEEATQYVEAMFRAFDTNGDNTIDFLEYVAALNLVLRGTLEHKLKWTFKIYDKDRNGCIDRQELLDIVESIYKLKKACSVEVEAEQQGKLLTPEEVVDRIFLLVDENGDGQLSLNEFVEGARRDKWVMKMLQMDLNPSSWISQQRRKSAMF
What is the function of this protein?
Stimulates two retinal guanylyl cyclases (GCs) GUCY2D and GUCY2F when free calcium ions concentration is low, and inhibits GUCY2D and GUCY2F when free calcium ions concentration is elevated (PubMed:7665624).  This Ca(2+)-sensitive regulation of GCs is a key event in recovery of the dark state of rod photoreceptors following light exposure (PubMed:9651312).  May be involved in cone photoreceptor response and recovery of response in bright light (By similarity).
What are the official names of this protein?
Guanylyl cyclase-activating protein 2, GCAP 2, Guanylate cyclase activator 1B, Retinal guanylyl cyclase activator protein p24.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Photoreceptor inner segment. Cell projection, cilium, photoreceptor outer segment. Note=Subcellular location is not affected by light or dark conditions.
Protein: PXPA_BURTA
Sequence: MEIDLNADLGEGCGSDEALLDLVTSANIACGWHAGGAPAMRDCVRWAVEKGVSIGAHPSFHDPENFGRKEMDLPASEIYAGVLYQLGALSAIAQAEGGRIAHVKPHGALYNQAARDAEIADAVVSAIHDFDPSLAVFGLASSGFVDAARHAGLVAVEEVFADRGYRADGSLVPRSQPGALVDDEREMLARTLEMVRGQRVRAVTGEWVPLNAQTVCLHGDGPHALAFAKRIREALEAAGIDVHAPGALHAGERA
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: ISPF_CHLTA
Sequence: MTEIPSSFVLPDPEWIYRVGIGQDSHRFLPDEDPKPCILGGIIFENTPGFEANSDGDVVFHAICNAFSSVTHKGILGGLADELLKTKGITDSVVYLQEAVASLKPTQQVSHLAITIEGKRPKLLPQLPSMRKRIAEVLHIPLDSINITATSGEGLTAMGQGYGVQCFCVLTIMEYCRY
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: SLA2_TRIAB
Sequence: DFHCLPGWSAYDQYCYRVFNEPKNWEDAERFCAKQADSGHLVSIETMGEADFVAQLISENIQSEKHYVWIGLKVQNKEQQCSSEWSDGSSVTYENLIKLYMRKCGALEQESGFRKWINLGCIQLNPFVCKFPPQ
What is the function of this protein?
Potent platelet activator that aggregates platelets via both GPIbalpha (GP1BA) and GPVI (GP6).  Induces a tyrosine phosphorylation profile in platelets that resembles this produced by collagen, involving the time dependent tyrosine phosphorylation of Fc receptor gamma chain (FCGR1A), phospholipase Cgamma2 (PLCG2), and LAT.
What are the official names of this protein?
Snaclec alboaggregin-A subunit alpha', Alboaggregin-A subunit 2, AL-A subunit 2.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: NDUV1_ASPNG
Sequence: MISRAAAPSSSIASLSSRSLRAQAPAARSFATVQDNAPPVKHYGGLKDQDRIFTNLYGHHGADLKSAMKYGDWHRTKDIVLKGHDWLISELKASGLRGRGGAGFPSGLKYSFMNFKDWDKDPRPRYLVVNADEGEPGTCKDREIMRKDPQKLIEGCLVVGRAMNANAAYMYIRGEFYQEATVLQRAINEAYEAGLIGKNACGTGYDFDVYIHRGMGAYVCGEETSLIESIEGKAGKPRLKPPFPAAVGLFGCPSTVTNVETVAVTPTIMRRGASWFSSFGRERNAGTKLFCISGHVNNPCTVEEEMSISLRDVIDRHCGGVRGGWDNLLAVIPGGSSTPVLPKTICDDQLMDFDALKDSQSGLGTAAVIVMDKSTDIVRAISRLSTFYKHESCGQCTPCREGSKWTMHMMQRMEKGQAREREIDMLQELTKQVEGHTICALGEAFAWPIQGLIRHFRPELEARIREYSKEVGGNGPYAGGWHPEARAEGKLISPGM
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase 51 kDa subunit, mitochondrial, Complex I-51kD, CI-51kD.
What is the protein family that this protein belongs to?
Belongs to the complex I 51 kDa subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: TCTP_XENTR
Sequence: MIIYKDTVTEDEMFSDIYKIAETPDGMCFEVEGKIIQRVEGAIDDALIGGNASAECQEEDIGGATTVSGVDIVINHKLQETGFTKDSYKNYIKDYVKLVKAKLEETDPDRVKPFMKGIQDRVKLILGNFKNYQFYTGERMNPDGMVALLDYREDGVTPFMIFFKDGLISEKC
What is the function of this protein?
Involved in calcium binding and microtubule stabilization.
What are the official names of this protein?
Translationally-controlled tumor protein homolog, TCTP.
What is the protein family that this protein belongs to?
Belongs to the TCTP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AQR1_CANGA
Sequence: MVESGPHSINDDLSTNEYIEQPKFYHDDHASDSNSLSDIDDDNKKHGGLYGTVSRTTTRELPEDLESEISSTHSQDAKEDLEIQHNAAPYSLLNYRDKWCMVALLTACGFWSSLGSPIYYPALKQLEKQFDIDENMVNITVVVYLLFQGLAPTCSGGLADKFGRRPVLLIGMLIYVVASIGLACAPSYGVIVFLRCVQSIGISPSIAISSGVVGDFTVKSERGTFVGATSGFVLLGQAFGSLIGAALAAAWDWRAIFWFLTIGCGASFAICFALLPETKRSIVGNLSIRPKNPLNIAPVTLLPAARRKLKYDNPDYETLDKTKPVFDLTSAFKICALPEIFLSLLPPGLAFAMWTLMLSAISSELSAAPYNYKLTIIGVCYLPAGIGGLIGSFATGKIIDFQYKKKLKVFEEKKAAGIIPEDEKFNIMGARLQSVLPQNFLCVVTYILFGWSCDKGWKIPSILITSCVSSFCAMSTLSAMSTLLVDLYPGKSSTASSCFNFMRCSLSAILMGCFAKMKHSLTVGGTFTLLAGLVFVGNFLMFIPMKHGMRWREEREQRAALKAKSMDQANENGYKLFSKIKFSSPFKSEEKV
What is the function of this protein?
Multidrug transporter acts as a determinant of resistance to acetic acid, flucytosine and clotrimazole, these 3 compounds acting synergistically against the pathogen (PubMed:23805133, PubMed:27148215).  Reduces the intracellular accumulation of the antifungal agents flucytosine and, to a moderate extent, of clotrimazole (PubMed:23805133).  Its role in acetic acid resistance may be indirect, presumably through the transport of a still unidentified physiological substrate (PubMed:23805133).
What are the official names of this protein?
Multidrug transporter AQR1, Drug:H(+) antiporter AQR1, DHA AQR1, Flucytosine exporter AQR1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. CAR1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Localizes also to membrane vesicles (PubMed:23805133).
Protein: GYRA_STAEP
Sequence: MAELPQSRINERNITSEMRESFLDYAMSVIVSRALPDVRDGLKPVHRRILYGLNEQGMTPDKPYKKSARIVGDVMGKYHPHGDSSIYEAMVRMA
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_CHLP8
Sequence: MFDKLQSIKDKYLTIEQQLSDPEVAADQNRFRKLNKEYSGLREIVRAYDNWRSAKQQLDETLAMQKSEEDPEMRALAAAEAEELQERLPELEQNLKILLLPKDEADTRNAIIEIRAGTGGDEAGLFAADLMRMYQRYAERQGWSCQTLDVSEGSVPGSLKEVSLEVSGHDVYGILKFESGVHRVQRVPETETQGRIHTSAASVAVLPEAEEVDVEIRKDDLQMDTFRSGGKGGQNVNKVETAVRITHVPSGIVVACQEERSQLQNRERAMKMLRSKLYDIKITEQLQSRADLRRSMVATGDRSAKIRTYNFPQSRVTDHRIGFTTHALPQVMQGELEPIIDALRMHDQAERLKAETN
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.