PharMolix/UniProtQA huggingface dataset:
Protein: IZH1_ASHGO
Sequence: MSEERGMKEQTISEMAQEMAHTTSEGLKKRIRKLYTFDELPAWQKDNELILSGYVRETNSVKECLRAMTYFNNESINIYTHLIPGVAYLVLFLIFADLVLAQLLPGLDAGEHRMLRFYLLGAFTCLACSSCFHCLKQHSEPHSRLWSKVDYLGILAQITCSTISLLYYGYHSYPSHFVFFSTLTVALCSACAVLVLNDSFNTVAFRPLRAFLFMAFGLSGVIPVLAGSYQFGFAEWAARIQLKYVLYEAVFYITGALVYGFRIPERFAPGKFDMVGHSHQIFHLLVVLGTLCHFRAVTGSYIFICTGKHYSSLLMFI
What is the function of this protein?
ADIPOR-like receptor involved in zinc metabolism either by altering membrane sterol content or by directly altering cellular zinc levels.
What are the official names of this protein?
ADIPOR-like receptor IZH1.
What is the protein family that this protein belongs to?
Belongs to the ADIPOR family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: Y1162_METVS
Sequence: MDPEEIKQKKLQEMQAKAQDPEYQRQMQEQQMQYEMQKQKVLRQILSEEARSRLARIKLAKPEFARQVESQLIQLAQAGRLPVPLTDEYFKGLLDKIYEMNKSTKREVTITRR
What are the official names of this protein?
DNA-binding protein Mevan_1162.
What is the protein family that this protein belongs to?
Belongs to the PDCD5 family.
Protein: RK16_NEOYE
Sequence: MLSPKKTKFRKQHRGRMKGSASKGNTIAFGDYALQATEPVWLTSRQIEATRRTITRYVRRGGKLWIRVFPDKPVTARPAETRMGSGKGAPEYWVAVIKPGHILFEITGVPQKTAQQAMKLASYKLPIKTKFIVRNTTES
What are the official names of this protein?
50S ribosomal protein L16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PA_I60A0
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDLKIETNKFAAICTHLEVCFMYSDFHFINEQGESIIVELDDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFHQSERGEETIEERFEITGTMRRLADQSLPPNFSCLENFRAYVDGFEPNGYIEGKLSQMSKEVNAKIEPFLKTTPRPIRLPDGPPCSQRSKFLLMDALKLSIEDPSHEGEGIPLYDAIKCMRTFFGWKEPYVVKPHEKGINPNYLLSWKQVLAELQDIENEEKIPRTKNMKKTSQLKWALGENMAPEKVDFDDCRDVSDLKQYDSDEPELRSLSSWIQNEFNKACELTDSIWIELDEIGEDVAPIEHIASMRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKWEKYCVLEIGDMLLRSAIGQVSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAESSVKEKDMTKEFFKNKSETWPIGESPKGVEEGSIGKVCRTLLAKSVFNSLYASPQLEGFSAESRKLLLVVQALRDNLEPGTFDLGGLYEAIEECLINDPWVLLNASWFNSFLTHALR
What is the function of this protein?
Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits.  The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching.  It consists in the hijacking and cleavage of host capped pre-mRNAs.  These short capped RNAs are then used as primers for viral mRNAs.  The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
What are the official names of this protein?
Polymerase acidic protein, RNA-directed RNA polymerase subunit P2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=PB1 and PA are transported in the host nucleus as a complex.
Protein: FSHB_LITCT
Sequence: CELSNITIVLEKEECGACVSVNATWCSGYCYTKDANLMYPQKSEKQGVCTYTEVIYETVKIPGCAENVNPFYTYPVAVDCHCGRCDSETTDCTVRALGPTYCSLSQD
What is the function of this protein?
Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer.  Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways.  Follitropin is involved in follicle development and spermatogenesis in reproductive organs.
What are the official names of this protein?
Follitropin subunit beta, Follicle-stimulating hormone beta subunit, FSH-B, FSH-beta, Follitropin beta chain.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit beta family.
What are the subcellular locations of this protein?
Secreted. Note=Efficient secretion requires dimerization with CGA.
Protein: AGLE_HALVD
Sequence: MTSTLPFVSVIIPVYNEAENIQKCLNAVTSQTYPKSKYEVLVVDNGSQDGTKEIARQFSTAYDNLEILIEDEQQGSYAARNTGIEQSSGAILAFLDGDCSPHQQWLERGVSTISGTGVDLVGGNVEFTYPNGGTAAERYDSFTNMQMKESISKRNVAKTVNLFVRQDVVEDVGPFPNHLISGGDVHWTKRATDAGYSLTFAHDVIGCHPARPFGELLKKQFRVGKGQIQVWMLDRISLRRVFALALWILVGFLPKPPHYLSQDLRRTGQTVTKAMFVRILVVAWCCRLAENAGRLSYILRSEEQ
What is the function of this protein?
Involved in the assembly of a N-linked pentasaccharide that decorates the S-layer glycoprotein and flagellins.  Catalyzes the addition to the dolichol phosphate carrier of the hexuronic acid found at position 4 of the pentasaccharide.
What are the official names of this protein?
Glycosyltransferase AglE, Archaeal glycosylation protein E.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Cell membrane. Note=Could be an integral membrane protein.
Protein: GCY20_CAEEL
Sequence: MRILLLLLQNILVFCQFLQTIKVGLMFSKDTASVIRSVGYRTSAAAVLVAKDRIRAEHLLDQYDFNFTIKFDECSESLAAGKVVELLTHDNVDVIIGPTCNRAGVAVASLADFYNVPVFQWGLTTTADIGNFSRYQTTVTLSLDTHSISLAVREILRQYGWSEFVFIYSNDGDEEKCAAMKDDMEKMGIENSDVTMAYMIQIQTVTMESLQRTLLEVSKRGRIIIACFASGRGFKKAFIASTVLAGMSTEEYLYVFAEPQSRGFYVDEADGKVHYSWDDTDGQLVTGLTNEQIRDAYGKVLYICDNMGEPTTITTQYTNFTSQVISRMAEQPFNCVQDCSNQSYKHAATYAGQLADSFYAYAFALNKSLTQDPTRSNLKNGSFVLSNIGMTFQGVGGEAVTLDESGSRIVQVYMFAMNSSLLPYMAASLLVNVSEVVFTPFYKSESELWSVRPLSRPKCGFTGLECPADFVKEYLVYTIIAAFIVILALLAGCAGLLYTMHMKRKEMERQDLLWQVAFVELQQVQSKSRAEASMHSFASGPSTSTKMTVESRTETTNFIFYHYHQEVVAAKKHDLLVLFDANQKSEFRQMRNFDNDNLNKFIGLCLDGPQLLSLWRFCSRGSLSDVISKSSMQMDSFFMFSLIRDISNGLYFIHSSFLKCHGQLTSRCCLIDDRWQIKISGFGLKSVRTFENPKKEDLLWASPEYLRNEDQERLPEGDIYSFGIICAEILTRSSAFDLENRKEKPDVIIYQVKKGGHNPTRPSLDTGETVVINPALLHLVRDCWTERPSERPSIEQVRSHLNGMKDGRKTNLMDHVFNMLETYASTLEEEVSDRTKELTEEKKKSDVLLYRMLPRMVADKLKLGQTVEPETFEQVTIFFSDVVQFTTLAGKCTPLQVVTLLNDLYTIFDGIIEQNDVYKVETIGDGYLCVSGLPHRNGNDHIRHIARMSLGFLSSLEFFRVQHLPAERINLRIGINCGSVVAGVVGLTMPRYCLFGDAVNTASRMESNGKPGQIHVTAEANRMLTQVVGGFRTESRGEVIIKGKGVMETFWLLGEESGYTAPSKAAPKVIQHRQSIRSISPILEKNAEGSETSSLSVDQAGDNNSETV
What is the function of this protein?
Guanylate cyclase involved in the production of the second messenger cGMP (By similarity).
What are the official names of this protein?
Receptor-type guanylate cyclase gcy-20.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: NSP4_ROTMB
Sequence: MEKLADLNYTLGVITLLNDTLHNILEEPGMVYFPYIVSALTVLFTMHKASLPAMKLAMRTFQCSYRIIKRVVVTLINTLLRLGGYNDYLTDKDETEKQINRVVKELRQQLTMIEKLTTREIEQVELLKRIYDMMIVRHDSEIDMSKETNQKAFKTLHDWKNDRSYDDNTEVIAPL
What is the function of this protein?
The secreted form acts as an enterotoxin that causes phospholipase C-dependent elevation of the intracellular calcium concentration in host intestinal mucosa cells.  Increased concentration of intracellular calcium disrupts the cytoskeleton and the tight junctions, raising the paracellular permeability.  Potentiates chloride ion secretion through a calcium ion-dependent signaling pathway, inducing age-dependent diarrhea.  To perform this enterotoxigenic role in vivo, NSP4 is released from infected enterocytes in a soluble form capable of diffusing within the intestinal lumen and interacting with host plasma membrane receptors on neighboring epithelial cells such as integrins ITGA1/ITGB1 and ITGA2/ITGB1.
What are the official names of this protein?
Non-structural glycoprotein 4, NSP4, NCVP5, NS28.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP4 family.
What are the subcellular locations of this protein?
Host rough endoplasmic reticulum membrane; Single-pass type III membrane protein. Host membrane, host caveola; Single-pass type III membrane protein. Secreted. Note=NSP4 localizes also in vesicular structures which contain autophagosomal markers and associate with viroplasms in virus- infected cells. Additionally, a soluble form of glycosylated NSP4 is secreted despite retention of its transmembrane domain.
Protein: NODD1_RHILP
Sequence: MRFKGLDLNLLVALDALMTERNLTAAARSINLSQPAMSAAVGRLRTYFNDDLFTMVGRELVPTPRAERLAPSVREALLHIQVSIISWDPFCPAQSDRCFRVILSDYAALVFFEKVVTRVAREAPAVSFELLPIADNYDEYLRRGDADFLIFPELLMSRAHPKVALFEETLVCVGCHSNKLLSEQLTLERYMSMGHVVVKFGNARTASFEEWCLLGHGLKRHVEVVVQGFSMVPFMLSGTERIATMPLRLVKQLEKTIPLRIADLPLPLPAFTQALQWPALHNSGQASLWMRDVLCQEASRMPSPHEVMRRLRIS
What is the function of this protein?
NodD regulates the expression of the nodABCFE genes which encode other nodulation proteins.  NodD is also a negative regulator of its own expression.  Binds flavonoids as inducers.
What are the official names of this protein?
Nodulation protein D 1.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: YOMF_BACSU
Sequence: MADFAKLYNDPILSKKRIGSVEDPYLTYNETLTIFNGRALLTEIPNREFRVEVTGDNKEWREIEDGELDDNYFKVDYLMGVVFFNASNEGKSLTFNYSGEGASFFPASRIWIKRQGNMVIETLQGLIDEAEDTIIRMNERIAECERVTKRCQEVTAWCRQATSNYEEVVENTRKIYKPSVYTYSDIFTYYPTPQIGWTVTVKETKIVYRWDGFEWVDIGTSEVYEGFNILLSATEPFNANYIWYKDASFSPEKKRVVVSDTAPDSGQVWYKTD
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YomF.
Protein: COC2F_CONCL
Sequence: DVCESVAGRCIHNGCWCERSAPHGNCCNTSGCTARWWCPGTKWD
What is the function of this protein?
Mu-conotoxins block voltage-gated sodium channels.  This toxin reversibly blocks voltage-gated sodium channel in cephalopods, with no alteration in the voltage dependence of sodium conductance or on the kinetics of inactivation (By similarity).
What are the official names of this protein?
Mu-conotoxin-like Cal 12.1.2f, Conotoxin CalTx 12.1.3D.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1276_MYCTU
Sequence: MRHAKSAYPDGIADHDRPLAPRGIREAGLAGGWLRANLPAVDAVLCSTATRARQTLAHTGIDAPARYAERLYGAAPGTVIEEINRVGDNVTTLLVVGHEPTTSALAIVLASISGTDAAVAERISEKFPTSGIAVLRVAGHWADVEPGCAALVGFHVPR
What are the official names of this protein?
Uncharacterized protein Rv1276c.
What is the protein family that this protein belongs to?
Belongs to the SixA phosphatase family.
Protein: RBSD_STAAC
Sequence: MKKSAVLNEHISKAIATIGHFDLLTINDAGMPIPNDHRRIDLAVTKNLPRFIDVLATVLEEMEIQKIYLAEEIKEHNPTQLQQIKQLISSEIEIIFIPHEEMKSNLAHPLNKGNIRTGETTPYSNIALESNVTF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISR1_ASHGO
Sequence: MSAWASQEAAKEEEAVGDFARMLERRDAGLLARVLSRAQTGPEAYVRGLWRAEVGLERWRLTRVLGCGSVACVFELGDGALALKVPTSRRKAPVLLHEVLIYSHLAQQAGGRLAERHVVPFHGVAAVTRREYRRLRGGEVVPALVLERMDTTLEAVHRRAAVSKGQWWRYARDLVAALQFLRESCVVHGDIKTANVLVRGQDAFLADFTSAAVCDAAPEPLTTTLEYCAPGLIGGGQPTHSTDVYAAGLCLLALITRFEPFRELSMMKSHSSAPTHSLHETQWLMNAISKGDPIKYNVLSQDLYDRWAEELHFLRRFFVPAAQDALSRWLAESNARVAEHAF
What is the function of this protein?
Probable serine/threonine protein kinase which may function redundantly with MPK1-independent branch of the PCK1 pathway.
What are the official names of this protein?
Serine/threonine-protein kinase ISR1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: RL11_BACAC
Sequence: MAKKVIKMVKLQIPAGKANPAPPVGPALGQAGVNIMGFCKEFNARTADQAGLIIPVEITVFEDRSFTFITKTPPAAVLLKKVAGIESGSGEPNRNKVATVKRDKVREIAETKMPDLNAASVEAAMRMVEGTARSMGIVIED
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: SPEA_SHIFL
Sequence: MSDDMSMGLPSSAGEHGVLRSMQEVAMSSQEASKMLRTYNIAWWGNNYYDVNELGHISVCPDPDVPEARVDLAQLVKTREAQGQRLPALFCFPQILQHRLRSINAAFKRARESYGYNGDYFLVYPIKVNQHRRVIESLIHSGEPLGLEAGSKAELMAVLAHAGMTRSVIVCNGYKDREYIRLALIGEKMGHKVYLVIEKMSEIAIVLDEAERLNVVPRLGVRARLASQGSGKWQSSGGEKSKFGLAATQVLQLVETLREAGRLDSLQLLHFHLGSQMANIRDIATGVRESARFYVELHKLGVNIQCFDVGGGLGVDYEGTRSQSDCSVNYGLNEYANNIIWAIGDACEENGLPHPTVITESGRAVTAHHTVLVSNIIGVERNEYTVPTAPVEDAPRALQSMWETWQEMHEPGTRRSLREWLHDSQMDLHDIHIGYSSGTFSLQERAWAEQLYLSMCHEVQKQLDPQNRAHRPIIDELQERMADKMYVNFSLFQSMPDAWGIDQLFPVLPLEGLDQVPERRAVLLDITCDSDGAIDHYIDGDGIATTMPMPEYDPENPPMLGFFMVGAYQEILGNMHNLFGDTEAVDVFVFPDGSVEVELSDEGDTVADMLQYVQLDPKTLLTQFRDQVKKTDLDAELQQQFLEEFEAGLYGYTYLEDENLLI
What is the function of this protein?
Catalyzes the biosynthesis of agmatine from arginine.
What are the official names of this protein?
Biosynthetic arginine decarboxylase, ADC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: PDXT_METM7
Sequence: MKIMGILGIQGDLEEHEDAVRKVNCIPKRIRTVDDLDGIDALIIPGGESTTIGKLMVSYGFIDKIRNLKIPILGTCAGMVLLSKGTGKEQPLLEMLNVTIKRNAYGSQKDSFEKEIVLGGKKVHAVFIRAPQVGEILSKDVEIISKDDGNIVGVKEGNIMAISFHPELSEDGVIVYEYFLKNFVEKN
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: Y904_MYCBO
Sequence: MLDSDARLASDLSLAVMRLSRQLRFRNPSSPVSLSQLSALTTLANEGAMTPGALAIRERVRPPSMTRVIASLADMGFVDRAPHPIDGRQVLVSVSESGAELVKAARRARQEWLAERLATLNRSERDILRSAADLMLALVDESP
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator Mb0904.
Protein: KHSE_RHOPA
Sequence: MAVYTDVAADELADFLSRYDIGDLLSYKGIAEGVENSNFLLHTSRGYFILTLYEKRVARDDLPFFLSLMTHLADSGINCPQPVADREGRTLATLAGRPAAIISFLDGVWPRKPSVVHCAGVGQALAKMHLAGRDFAMKRANALSVAGWRPLFAAAEARADEVQPGLRDFLAAELSYLESGVWPSDLPQGLIHADLFPDNVFFIGDEVSGIIDFTFACNDLLAYDVAICLNAWCFEADHAFNVTKARALLSAYTRERPLDAAEQAALPLLARGAALRFLLTRLVDWLNVPEGALVKPKDPMEYVRKLRFQQNVAGIRDYGVEIAGAVA
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the pseudomonas-type ThrB family.
Protein: UBIG_SHESA
Sequence: MQQNTNVDPLEIAKFERMAETWWDLNGEFKPLHLLNPLRLNYIDQTAGGIFGKKVLDVGCGGGILSESMARIGAIVHGLDMGEEPLEVARLHALETGVSINYVKNTAEAHREEHREYYDVVTCMEMLEHVPDPQSVIQACCDMVKPGGFVFFSTINRNIKSFVETIIGAEYLLKMLPIGTHDHNKFIKPSELMALVDNTDLLCKDALGITYNPLTGIFKYTPKVDVNYMIATQKVD
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: MRSA_PSESY
Sequence: MNLLDSIKSENTGFETTLIKGIEPIRQFVLAISIYHLFDTKLFSLLIKHEVASPEVACNELGMEKEKLLGLFRYLKNEGILLETIDGFSLSKEGHALAPFEGWYVMLVGGYATTFLQMGERLQEGAGWATRDATKVGVGSCGISHFDAIPLTRSLMAQAPGTCTKLLDLGCGNGRYLAEFCKALPQIQAWGAEPDRGGFEEAVDLIEKEGLSHRVHISHSGAVEFLDSDFDFEPDFIVLGFVLHEILGQAGRPAVVNFLKKIVHRFPAINLIIIEVDNQFDNAGAMRHGLALAYYNPYYLLHCFTNQLLVQDADWLDIFAEAGLSLVTRETTSDQVDSTGLEIGYLLRRA
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase involved in the formation of 3-methylarginine (MeArg), a potent antibiotic against the closely related soybean pathogen P. syringae pv.  glycinea.  Transfers the methyl group from S-adenosyl-L-methionine into 5-guanidino-2-oxopentanoate acid to yield 5-guanidino-3-methyl-2-oxopentanoate5-guanidino-3-methyl-2-oxopentanoate, a precursor of MeArg.
What are the official names of this protein?
2-ketoarginine methyltransferase.
Protein: YBED_SHIFL
Sequence: MKTKLNELLEFPTPFTYKVMGQALPELVDQVVEVVQRHAPGDYTPTVKPSSKGNYHSVSITINATHIEQVETLYEELGKIDIVRMVL
What are the official names of this protein?
UPF0250 protein YbeD.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.
Protein: XERD_STAAS
Sequence: METIIEEYLRFIQIEKGLSSNTIGAYRRDLKKYQDYMTEHHISHIDFIDRQLIQECLGHLIDQGQSAKSIARFISTIRSFHQFAIREKYAAKDPTVLLDSPKYDKKLPDVLNVDEVLALLETPDLNKINGYRDRTMLELLYATGMRVSELIHLELENVNLIMGFVRVFGKGDKERIVPLGDAVIEYLTTYIETIRPQLLKKTVTEVLFLNMHGKPLSRQAIWKMIKQNGVKANIKKTLTPHTLRHSFATHLLENGADLRAVQEMLGHSDISTTQLYTHVSKSQIRKMYNQFHPRA
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerD.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_IGNH4
Sequence: MGDPRKPRKKWSPPGHPWVKERLIEEMKLMGEYGLRNKREIWIAAAMLRRYRHRARELLALPAEVREKEEKALLKRLYDLGLVDENATLDDVLSLTVRDLLERRLQTVVYKKGLAKSIYHARQLVTHGHIAINGRRVTSPGYIVRRDEEELIGYAPTSPYFKKAQQ
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: IKBZ_HUMAN
Sequence: MIVDKLLDDSRGGEGLRDAAGGCGLMTSPLNLSYFYGASPPAAAPGACDASCSVLGPSAPGSPGSDSSDFSSASSVSSCGAVESRSRGGARAERQPVEPHMGVGRQQRGPFQGVRVKNSVKELLLHIRSHKQKASGQAVDDFKTQGVNIEQFRELKNTVSYSGKRKGPDSLSDGPACKRPALLHSQFLTPPQTPTPGESMEDVHLNEPKQESSADLLQNIINIKNECSPVSLNTVQVSWLNPVVVPQSSPAEQCQDFHGGQVFSPPQKCQPFQVRGSQQMIDQASLYQYSPQNQHVEQQPHYTHKPTLEYSPFPIPPQSPAYEPNLFDGPESQFCPNQSLVSLLGDQRESENIANPMQTSSSVQQQNDAHLHSFSMMPSSACEAMVGHEMASDSSNTSLPFSNMGNPMNTTQLGKSLFQWQVEQEESKLANISQDQFLSKDADGDTFLHIAVAQGRRALSYVLARKMNALHMLDIKEHNGQSAFQVAVAANQHLIVQDLVNIGAQVNTTDCWGRTPLHVCAEKGHSQVLQAIQKGAVGSNQFVDLEATNYDGLTPLHCAVIAHNAVVHELQRNQQPHSPEVQELLLKNKSLVDTIKCLIQMGAAVEAKDRKSGRTALHLAAEEANLELIRLFLELPSCLSFVNAKAYNGNTALHVAASLQYRLTQLDAVRLLMRKGADPSTRNLENEQPVHLVPDGPVGEQIRRILKGKSIQQRAPPY
What is the function of this protein?
Involved in regulation of NF-kappa-B transcription factor complexes (PubMed:16513645, PubMed:16622025).  Inhibits NF-kappa-B activity without affecting its nuclear translocation upon stimulation (PubMed:16513645).  Inhibits DNA-binding of RELA and NFKB1/p50, and of the NF-kappa-B p65-p50 heterodimer and the NF-kappa-B p50-p50 homodimer (PubMed:16513645).  Seems also to activate NF-kappa-B-mediated transcription (PubMed:16622025).  In vitro, upon association with NFKB1/p50 has transcriptional activation activity and, together with NFKB1/p50 and RELA, is recruited to LCN2 promoters (PubMed:16622025).  Promotes transcription of LCN2 and DEFB4 (PubMed:16622025).  Is recruited to IL-6 promoters and activates IL-6 but decreases TNF-alpha production in response to LPS (By similarity).  Seems to be involved in the induction of inflammatory genes activated through TLR/IL-1 receptor signaling (By similarity).  Involved in the induction of T helper 17 cells (Th17) differentiation upon recognition of antigen by T cell antigen receptor (TCR) (By similarity).
What are the official names of this protein?
NF-kappa-B inhibitor zeta, I-kappa-B-zeta, IkB-zeta, IkappaBzeta, IL-1 inducible nuclear ankyrin-repeat protein, INAP, Molecule possessing ankyrin repeats induced by lipopolysaccharide, MAIL.
What are the subcellular locations of this protein?
Nucleus. Note=Aggregated in dot-like structures (PubMed:16513645). Colocalizes with NCOR2 (PubMed:16513645).
Protein: SP2E_PRIMG
Sequence: TVGVVTGLILSFANVSSLYEMSLLAFSGLLGGLLKDGKKLGARLGLVVGSLLIGLYAQADQGLTTNLYESLTAVVLFLLTPSFVLKNLSKLVPGTSENMLEQQQYVRKIRDVTANRVEQFSNVFQALSKSFTQNGFYDEKPSADKEVDYFLSSVTERTCQFCFKKEQCWAQQFDTTYEYMKEIMLEVDNGTLEQNPRLIREMDKHCVKSKKVIDVIEHELTYFKANQHLKAQIQESRRIVAEQLHGVSEVMGNFAKEIKRERENLNVQEEQILEALRNFGMEINQIEIYSLEPGNVDIEMWVPYCHGRGECEKIIAPMLTDILGESIVVKNEECAKYPQGYCHVSFGCTKAYVVDTGVAHAAKGGGFVSGDSYSMIELNAGKYALAISDGMGNGERAHYESSETLQLLKQILQTGIEETIAIKSINSILSLRTNDEIFSTLDLAMIDLQDANVNFLKIGSTPSFIKRGDKVIKIQASNLPMGIIEEFEVDVVNEQMKAEDLLIMMSDGVFEGPKHVENYEMWMKRKIGELQTNDPQEIADLIMEEVIRTKVGLIEDDMTVVVAKLQHNTPKWSSIPSYAYRNLAQ
What is the function of this protein?
Normally needed for pro-sigma E processing during sporulation but can be bypassed in vegetative cells.  Activates SpoIIAA by dephosphorylation (By similarity).
What are the official names of this protein?
Stage II sporulation protein E.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Polar septum.
Protein: MTD_METPE
Sequence: MVVKVGIAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVSTMKAWEPDFCIVVSPNGVLPGPVGARDELLKAGIPCVVITDDITTKKEGWEALKASSFGYIIMKADAMIGARREFLDPVEMADFNGNLVKVLALTGAFRKLQTELDKVIDQVKEGKKGADLVLPKVVMTSDKAVDGEFSNPYALAKARAAYEIAQAVAGVNVKGCFMTKEWEKYIPIVASAHEMMRQAAALGDEAREIEKAGNGIIRKPHKKDGTIVSKITLISKPE
What is the function of this protein?
Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.
What are the official names of this protein?
F420-dependent methylenetetrahydromethanopterin dehydrogenase, MTD, Coenzyme F420-dependent N5,N10-methylenetetrahydromethanopterin dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MTD family.
Protein: GLMU_SYNE7
Sequence: MVAVAILAAGKGTRMKSQLPKVLHRLGSQTLLDRVLASLTPLNVDRCFVIVGYQGDRVRESWAHRTDIEFVEQTQQLGTGHAVQQLLPHLKGYQGDLLVLNGDVPLLRGETLEALVSGHQRSGAAATLLTAQLNQPKGYGRVFCDATSRVCEIIEDRDCTPAQRQNPRVNAGVYCFRWPDLEAVLPNLSTANDQQEYYLTEAITYLDPVSAVEVADSQEILGINDRLQLADSFRILQERIRQQWMLAGVTLVDPTSITIDETVQLGTDVVIEPQTHLRGNTVIGNNCSIGPNSLITNSQIGDGVTVQMSVISDSTIAANSKIGPFAHLRGAAAIGEACRIGNFVEVKKSTVGDRTNVAHLSYLGDATLGQRVNVGAGTITANYDGVSKHPTVIGDRSKTGANSVLVAPVTIGQDVTIAAGSTINKDVPDGALAIARSRQTIHENWSTPTTEQ
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.