PharMolix/UniProtQA huggingface dataset:
Protein: YJJB_SALPA
Sequence: MGIIDFLLALMQDMILSAIPAVGFAMVFNVPHRALPWCALLGALGHGSRMLMMSAGFNIEWSTFMASLLVGSIGIQWSRWYLAHPKVFTVAAVIPMFPGISAYTAMISAVKISHLGYSEPMMITLLTNFLKASSIVGALSIGLSVPGLWLYRKRPRV
What is the function of this protein?
Involved in succinate export with YjjP.  Both proteins are required for export.
What are the official names of this protein?
Probable succinate transporter subunit YjjB.
What is the protein family that this protein belongs to?
Belongs to the ThrE exporter (TC 2.A.79) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PLAL1_PIG
Sequence: MATYPCQLCGKTFLTLEKFTIHNYSHSRERPYKCLQPDCGKAFISRYKLMRHMATHSPQKSHQCAHCEKTFNRKDHLKNHLQTHDPNKMAFGCEECGKKYNTMLGYKRHLALHAASSGDLTCGVCALELGSTEVLLDHLKAHAEEKPPSGTKEKKHQCDHCERCFYTRKDVRRHLVVHTGCKDFLCQFCAQRFGRKDHLTRHTKKTHSQELMKESLQSGDLLSTFHSISPQFQLKAAPLSPFPLGAPAQNGLASSLPAEVHSHTHNPSEQTSQPVQALPELLAPLHPVAPPTSPPQPLQNHKYNTSSTSYSPLASLPLKADTKGFCNTNLLEDLPLQEPQSPHKLNPGFDLAKGGAGKVNLPKELPADAVNLTIPASLDLSPLLGFWQLPPPATQNAFGNSTLTLGPGESLPHRLSCLGQQQQDPSLAMSTMSLGQLPLPPIPHVFPAGTGSAILPHFHHAFR
What is the function of this protein?
Acts as a transcriptional activator.  Involved in the transcriptional regulation of type 1 receptor for pituitary adenylate cyclase-activating polypeptide.
What are the official names of this protein?
Zinc finger protein PLAGL1, Pleiomorphic adenoma-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DEF3_TRIKH
Sequence: RDCKSDSHKFHGACFSDTNCANVCQTEGFTRGKCDGIHCHCIKDC
What is the function of this protein?
Plant defense peptide.
What are the official names of this protein?
Defensin Tk-AMP-D3.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
Protein: FOXR2_MOUSE
Sequence: MDVKVKNRDFWYSLHGQVPGMLDWDMGNEFFLPCTMDQCSFAEQSLAKYKIQLTKPPALPQKKKSNFDDDGPPAEPSLWMWVNPNIVCPINSKEAPNTIHKILPSAPFPQTGESDYLGTQRMVQSLSVLHTEHHQQQKLLIYSTAPDFIEEETKEQECTSSKKYSKKHTVCHGPHREKESWPRPPLNYSHLVALALKSSPSCGLNVQQIYNFTRQHFPYFRTAPEGWKNTIRHNLCSLTCFEKVPVDLEDEPDGKPRSFLWKLTDEGNRFFQEDTRVLAYARRESIKQSMRQPELIDLLFHL
What are the official names of this protein?
Forkhead box protein R2, Forkhead box protein N6.
What are the subcellular locations of this protein?
Nucleus.
Protein: NRDR_STAAN
Sequence: MKCPKCNSTQSKVVDSRHADELNAIRRRRECENCGTRFTTFEHIEVSQLIVVKKDGTREQFSREKILNGLVRSCEKRPVRYQQLEDITNKVEWQLRDEGHTEVSSRDIGEHVMNLLMHVDQVSYVRFASVYKEFKDVDQLLASMQGILSENKRSDA
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: TRA1_COMTE
Sequence: MQGWHTTFLGMRGLPRDISDFEMKAFFTFDGAERDAINARRGDSHKLGLALHIGFLRMSGRLLGAFRVIPVALWRHLGNELGIAAPEVASLRAMYERGRTLFDHQQVACTVLGFQWMSEHQRRSLVRELRDEVAGCDRDQLLVRARQWLYKNKLVIVHERAIRTLIAAALAQLEVETGTAIAASVDPATLDRWRASVSELRPDGQTQQSWLWAAPAKHSTRQISEVLERIDLLYTLDVHKHLADIPDLILRRYARRLVSRPPSAGAKIKEPARTVEVACFLRYCLFTTTDQLILMVQRRIADLWRQAAADVPATVNWAAMYKTLLGELVALSAQGAVPDAELRARLEALITETQKRKPPSRASLVREGLIDGIRPVRSLLVAIAKLPWQATGEHPAIEYLAKLQALYLKGSRKLPVEVVAPSLGMIWQVSISSPDRERAFQALEVATLFALRRAVRNGSVWIEHSLSFRGRARLFFTDERWQAESKKHYARLSLPSKAATFLKPLLARVTAGVDAVAAAARSGVLRVDDELHLSPLPAEDEDPEVTKLRAALDHRIGEVQLPEVILAVDAQVRFSWIMLGREPRSTDELLMVYAGIMAHGTSLTAVECARMIPQLSATSIRQAMRWARDERRLSQACQAVLEFMQRHPIAATWGRSDLASSDMMSMETTKRVWQARLDPRRNTPSIGIYSHVKDRWGIFHAQPFVLNERQAGVAIEGVIRQEKLETSQLAVDTHGYTDFAMSHARLLGFDLCPRLKELKQRHLFVPRGTKVPAEIAAVCEANVDVALIEKHWDSLVHLAASVMSGHASAVAALARFGSAAQGDPIYEAGVQLGRLLRTAFLADYFVKDAFRNELRRVLNRGEAVNALKRAIYTGRISPAQAKRVDEMQAVADALSLMANIVMAWNTSQMQAVLDRWSNRRQVIPPELIGKIAPTRLESINLRGVFRFPVDRYADQILPSRPNASITGTNG
What is the function of this protein?
Required for transposition of transposon Tn5271.
What are the official names of this protein?
Transposase for insertion sequence element IS1071 in transposon Tn5271.
What is the protein family that this protein belongs to?
Belongs to the transposase 7 family.
Protein: YUEF_BACSU
Sequence: MLKSKVHFWTLQILFVLLIIFVATKVSFVFQPFIVFISTLFFPMLIAGILYFIFNPVVRLLEKKIPRTLSILLIYLLFIGLLAFISASVGPIITAQVTGLFNNLPDYIKQIQALTKDLSHSQWFTWMMNQDYVSISKIEQSLTSFLQNLPQNITSSLSAVFGVVTNITLVIITVPFILFYMLKDGHRFPHLAVKILPASYRTEGLKIFKDLSDTLAAYFQGQLLICLFVGTACFIGYLIAGLPYALILGIVMAITNIIPYVGPFLGAAPAVIVGFMDSPAKALFAIIVVVIVQQLDGNLLSPLVIGKRLNTHPLTIILLLIGAGSFGGILGMILAVPVYAVVKAFFLNIVRLIKLRQRSRLEENAKPAE
What are the official names of this protein?
Putative transport protein YueF.
What is the protein family that this protein belongs to?
Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RNPA_STAES
Sequence: MEKAYRIKRNSDFQAIYKNGKSVANRQFVVYTYKNRDLKHFRLGISVSKKLGNAVTRNRIKRAIRENFKVHKQNIIAKDIIVIARQPAKDMNTLEIQSSLEHVLKIAKVFNKKIK
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: PYRI_NATPD
Sequence: MTDTELRVSKIQKGTVIDHIAGGQALNVLAILGIDGTSGDEISVGMNVPSDRLGRKDIVKVEGRELSQNEVDVLSLIAPAATINIVRDFEVIEKHRVTRPETVEGVLSCPNANCITTENEPVDSRFEVLEAGVRCSYCGTIIRESLAAHISVA
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: GLMU_BURP1
Sequence: MNIVILAAGTGKRMRSALPKVLHPLAGRPLLSHVIDTARALAPSRLVVVIGHGAEQVRAAVAAPDVQFAVQEQQLGTGHAVRQALPLLDPSQPTLVLYGDVPLTRTATLKRLADAATDARYGVLTVTLDDPTGYGRIVRDQAGCVTRIVEQKDASPDELRIDEINTGIVVAPTAQLSMWLGALGNDNAQGEYYLTDVVEQAIEAGFEIVTTQPDDEWETLGVNSKAQLAELERIHQRNLADALLAAGVTLADPARIDVRGTLACGRDVSIDVNCVFEGDVTLADGVTIGANCVIRHAAIAAGARVDAFSHLDGATVGANAVVGPYARLRPGAVLAADAHVGNFVEVKNATLGQGSKANHLTYLGDADIGARVNVGAGTITCNYDGANKFRTVIEDDVFVGSDTQFVAPVRVGRGVTVAAGTTVWKDVAADMLVLNDKTQTAKSGYVRPVKKKS
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEPQ_ECO55
Sequence: MESLASLYKNHIATLQERTRDALARFKLDALLIHSGELFNVFLDDHPYPFKVNPQFKAWVPVTQVPNCWLLVDGVNKPKLWFYLPVDYWHNVEPLPTSFWTEDVEVIALPKADGIGSLLPAARGNIGYIGPVPERALQLGIEASNINPKGVIDYLHYYRSFKTEYELACMREAQKMAVNGHRAAEEAFRSGMSEFDINIAYLTATGHRDTDVPYSNIVALNEHAAVLHYTKLDHQAPEEMRSFLLDAGAEYNGYAADLTRTWSAKSDNDYAQLVKDVNDEQLALIATMKAGVSYVDYHIQFHQRIAKLLRKHQIITDMSEEAMVENDLTGPFMPHGIGHPLGLQVHDVAGFMQDDSGTHLAAPAKYPYLRCTRILQPGMVLTIEPGIYFIESLLAPWREGQFSKHFNWQKIEALKPFGGIRIEDNVVIHENNVENMTRDLKLA
What is the function of this protein?
Splits dipeptides with a prolyl residue in the C-terminal position.
What are the official names of this protein?
Xaa-Pro dipeptidase, X-Pro dipeptidase, Imidodipeptidase, Proline dipeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
Protein: Y2467_CERS4
Sequence: MTDLYIDADACPVKAEAERVAVRHGVRMFLVSNGGIRPPAHPLVESIFVPEGPDVADMWIADRARTGDVVVTSDIPLAAKVVAAGALVVKPNGETLTQANIGNALATRDLMADLRSADPFRQGGGRPFSKADRSRFLDALERAMRKAQEAGRSASGGNEAGS
What are the official names of this protein?
UPF0178 protein RHOS4_24670.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: PYRG_ANADE
Sequence: MVKRGKKTKYLFVTGGVVSSLGKGLSAASIGALLENRGLEVQHLKLDPYINVDPGTMSPFQHGEVFVTDDGAETDLDLGHYERFTSAKMTRRNNYTTGRIYQNVIQRERRGEYLGKTVQVIPHITDEIKAVIREAAGGADILIVEVGGTVGDIESLPFLEAIRQMKYDVGEENAVYAHLTLVPFIAAAGELKTKPTQHSVKELREIGIQPDLLLCRSDREIPRDMKDKIALFCNVDPSAVFTALDVPSIYEVPLSLHREGLDDKLAELFNIWSRAPRLERWETIVDKVKNPRRGEVRIGIVGKYVELHESYKSLNEALVHGGIANDARVKLAFIDSTKLEEGDLSDLDKVDAILVPGGFGIRGTEGKILGVKYAREHKVPFFGICLGLQMAVIEMARNVLGLAGANSLEFDEQTPHPVVTLMEGQKGVTDKGGTMRLGAYPCALKEGTKARALYGADLVHERHRHRFEFNNDYRAQFEAAGMVFSGVNPDLGLVEMIELPGQHFVGCQFHPEFRSKPFAPHPLFAGFVKAALEHRDAQQRQPSAEVKKLPVGKNG
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: URE1_ENT38
Sequence: MAEISRQAYADMFGPTTGDKVRLADTDLWIEVENDLTIYGEEVKFGGGKVIRDGMGQGQMTAQDCVDLVLTNALIVDHWGIVKADIGVKDGRIFAVGKAGNPDIQPGVTIPIGAATEVIAAEGKIVTAGGIDTHIHWICPQQAEEALVSGVTTMIGGGTGPAAGTNATTCTPGPWYIARMLQAADTLPVNIGLLGKGNGSNPDALREQIAAGAIGLKIHEDWGSTPATINCSLSVAEEMDIQVALHSDTLNEAGFVEDTLAAIDGRTIHTFHTEGAGGGHAPDIITACAHPNILPSSTNPTLPYTVNTIDEHLDMLMVCHHLDPDIAEDVAFAESRIRRETIAAEDVLHDIGAFSLTSSDSQAMGRVGEVIIRTWQVAHRMKVQRGALAEESGDNDNFRAKRYVAKYTINPALTHGIAHEVGSVEAGKLADLVVWSPAFFGVKPATIVKGGMIACAPMGDINASIPTPQPVHYRPMFGSLGAARHATRLTFISQAADANRIPQQLNLQSAIAVVKGCRTVKKADMIHNGLQPNITVDAQTYEVRIDGELITSEPADVLPMAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNME_BACCR
Sequence: MEFDTIAAISTALGEGAIAIVRVSGDDAVEKVDRIFKGKDLTEVPSHTIHYGHIVDLDTNQVIEEVMVSIMRAPRTFTRENIVEINCHGGLVSVNKVLQLILAQGVRLAEPGEFTKRAFLNGRIDLSQAEAVMDLIRAKTDRAMNVAINQMEGRLSKLIGLLRQEILETLAHVEVNIDYPEYDDVEEMTHNILIEKATHVRSEIEKILETSKQGKILREGIATAIIGRPNVGKSSLLNSLVQEKKAIVTDIAGTTRDVIEEYVNVRGVPLKLIDTAGIRETEDVVERIGVERSKEMMSQADLVLVVVNYSEALTNEDEDLFRAVQGKDFIVIVNKTDLPQAIDMERVTELAAGNRVITTSLIEEQGIDELEKAIADLFFEGTIDSADMTYVSNARHIGLLTQAGKTIGDAVEAIENGVPIDMVQIDLTRTWEILGEITGDTVHESLIDQLFSQFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OMP1_AGGAC
Sequence: VKVYNQFGTKVELGVSMRIF
What are the official names of this protein?
39 kDa major outer membrane protein.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: RL29_LEPIN
Sequence: MKKIKLQELKDSEILEQLEEARKVLRNSRFQYGVARSLENPKIISNTKKKIAKLLTIQRERQLKANPGERKSRVFSRAKRKKKNLARLSAKAKG
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: 17KD_RICMO
Sequence: MKLLSKIMIIALAASMLQACNGPGGMNKQGTGTLLGGAGGALLGSQFGQGKGQLVGVGVGALLGAVLGGQIGAGMDEQDRRLAELTSQRALETAPSGSNVEWRNPDNGNYGYVTPNKTYRNSTGQYCREYTQTVVIGGKQQKAYGNACLQPDGQ
What are the official names of this protein?
17 kDa surface antigen.
What is the protein family that this protein belongs to?
Belongs to the rickettsiale 17 kDa surface antigen family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: GAL1_THESQ
Sequence: MKVKAPGRINIIGEHTDYNDGYVLPFAVNRYVFLSIEGSDRFIFHSENVNETVEMEKIEKLNKWTDYISGVIASFEKRGYRVSPVKISVSSNLPMGAGLSSSAALEVATAYAISEYFSFNVPKLELVKIAREAEVEFVGVRCGIMDQFTSAFGKKDHAIFLDTMTLEYEYVPLRLEGYEINLVDSNVKHELSSSEYNKRRQECEEVLKTLGKKSFREVTKEDLERLSGTLRKRAQHVLEENERVLKSVQALKEGDFETLGKLLFSSHESLRDLYEVSCEETDFIVDYLRGKEGILGARMVGGGFGGGVIVLSKKGAFGKIKEELVESYKKHFGIDLTFHEIESSDGVQKI
What is the function of this protein?
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDGC_ACTPJ
Sequence: MFWFKNVMIYRLTSPLSLESSSLEEQLQQAKFTPCSQSDMSKFGWSSPLSGSELLHFSQGKQFLLVSHKEDKLLPANVIKKETEERIAVLEEKEARKLKKTEKQAIKDDVVAMLLPRAFSKHQFTAIWLDLDAQLVYVDAGSSKRAEDTLALLRKTLGSLPVVPISFALLPSEVMTNWIAKGHTPNWLNLLEEAELKSFDTDSVIRCKRQDLESEEIAQHLQAGKFVTKLAIDWENHFSCVLNEDATLSRVKFADEVREKNDDILKEDIAQRFDADFLLMTEELKLFTQKMIEEFGGIKERI
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: SYFA_CHLAB
Sequence: MAIQEELEATKQQFCAELSQVNSSKDLFDLKVRYLGKKGLFRCFADKLRECPADQKALMGASINDCKTYIENLIRDKNHAILLAEEAAEFLREKIDITLPGEPHCPGGKHIVKKVLDDVVDIFVHLGFCVREAPNIESEENNFSLLNFEEDHPARQMHDTFYLDPKTVLRTHTSNVQVRELRKGQPPIKVVAPGLCFRNEDISARSHVIFHQVEAFYLDRYVTLSDLTAMLTEFYHTFFEREIELRLRHSYFPFVEPGIEVDVSCECRQAGCSLCKHTGWLEVAGAGMIHPQVLRNSGFDPEIYTGYAVGMGIERLAMLQHGISDIRLFCENDLRFLQQFS
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NOTQ_ASPSM
Sequence: MAFTEPEVPELNGSTKGKYLCLTICGYRKPGMSEEDYRHHMVNISAPMTKGLMVKYGVKRWTQIHNQSSTRALMSHLFDSQMAIVADFDCFSQVVFKDIEHYKRMKQDPWYQEHLIGDHEKFADTRRSMMTIGWIEEFVRDGEVVEGFKDS
What is the function of this protein?
Probable decarboxylase; part of the gene cluster that mediates the biosynthesis of notoamide, a fungal indole alkaloid that belongs to a family of natural products containing a characteristic bicyclo[2. 2. 2]diazaoctane core (PubMed:20722388).  The first step of notoamide biosynthesis involves coupling of L-proline and L-tryptophan by the bimodular NRPS notE, to produce cyclo-L-tryptophan-L-proline called brevianamide F (PubMed:20722388).  The reverse prenyltransferase notF then acts as a deoxybrevianamide E synthase and converts brevianamide F to deoxybrevianamide E via reverse prenylation at C-2 of the indole ring leading to the bicyclo[2. 2. 2]diazaoctane core (PubMed:20722388).  Deoxybrevianamide E is further hydroxylated at C-6 of the indole ring, likely catalyzed by the cytochrome P450 monooxygenase notG, to yield 6-hydroxy-deoxybrevianamide E (Probable).  6-hydroxy-deoxybrevianamide E is a specific substrate of the prenyltransferase notC for normal prenylation at C-7 to produce 6-hydroxy-7-prenyl-deoxybrevianamide, also called notoamide S (PubMed:20722388).  As the proposed pivotal branching point in notoamide biosynthesis, notoamide S can be diverted to notoamide E through an oxidative pyran ring closure putatively catalyzed by either notH cytochrome P450 monooxygenase or the notD FAD-linked oxidoreductase (Probable).  This step would be followed by an indole 2,3-epoxidation-initiated pinacol-like rearrangement catalyzed by the notB FAD-dependent monooxygenase leading to the formation of notoamide C and notoamide D (PubMed:22188465).  On the other hand notoamide S is converted to notoamide T by notH (or notD), a bifunctional oxidase that also functions as the intramolecular Diels-Alderase responsible for generation of (+)-notoamide T (Probable).  To generate antipodal (-)-notoaminide T, notH' (or notD') in Aspergillus versicolor is expected to catalyze a Diels-Alder reaction leading to the opposite stereochemistry (Probable).  The remaining oxidoreductase notD (or notH) likely catalyzes the oxidative pyran ring formation to yield (+)-stephacidin A (Probable).  The FAD-dependent monooxygenase notI is highly similar to notB and is predicted to catalyze a similar conversion from (+)-stephacidin A to (-)-notoamide B via the 2,3-epoxidation of (+)-stephacidin A followed by a pinacol-type rearrangement (Probable).  Finally, it remains unclear which enzyme could be responsible for the final hydroxylation steps leading to notoamide A and sclerotiamide (Probable).  The fonction of notQ in the notoamide biosynthesis has not been determined yet (Probable).
What are the official names of this protein?
Probable decarboxylase notQ, Notoamide biosynthesis cluster protein Q.
What is the protein family that this protein belongs to?
Belongs to the tpcK family.
Protein: Y986_SHESM
Sequence: MLNTKFDELMEFPCAFPFKVVGDAHEALTDRVVAVVQRHAPGDYSPTVKASSKGSYYSVTIRVTVTSKDHIETLYTELAGIEGVRRVL
What are the official names of this protein?
UPF0250 protein Shewmr4_0986.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.
Protein: GCH3_METM6
Sequence: MIQITVVQIDNYGPWTVTPNPRRESDLQALQSRLYCDMNLQFGAHRGLAFYTRFDNIIAITNGIDLETHKRIQNSVKNRYPFTVSMAVASAETAYEAQKLATETIQEYGSAQDDVRKEVLDVANEFVSNGYVQLAHVDINDITGKLTDLETAYDTYLSVQMTKLKLMEELKKYDSMGFFIGGDNFMCPCNGMSEKDFLCMFEDIKESCGIDLKAGIGIGKTAEDASNLADIGLEVIREGKTDFQVYTLKQEIEERKDVTYNYMCPI
What is the function of this protein?
Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP.  Also has an independent pyrophosphate phosphohydrolase activity.
What are the official names of this protein?
GTP cyclohydrolase III.
What is the protein family that this protein belongs to?
Belongs to the archaeal-type GTP cyclohydrolase family.
Protein: LNT_YERPE
Sequence: MSIALFLQRQWVRALLALFFGACGTLAYSPFDHWPAAIVSLFGLLSLTLNRTTKQATFIGFCWGMGLFGSGINWVYVSISEFGGMPTAINIVLVILLAAYLSLYTMLFAGLLARLCPKATWWRLAIAAPVLWQLTEFLRGWVLTGFPWLQFGYSQINGPLRGIAPLLGVDGITFILMAISGLLVYACYQRRIVAAIIALALLLLPWPLRQIQWFTPEPERAVNIAMVQGNIAQSMKWDPKALITTLQIYLDETRPFMGKAPIIIWPESAIPDIETDQNTFLTMIDGLMRANHSSLITGIVDAKRQPEGQGYQFFNSIIVLGDKDTYQYPTRNRYSKHHLVPFGEYVPLESLLRPLAPLFNLPMSSFNRGDYVQPPLTIAGFNLTAAICYEIVLGQQVRDNFRPETDFLLTISNDAWFGHSIGPWQHFQMARMRALELGRPLLRSTNNGITAAIGPSGEILAQIPQFTQQVLEVKVTPTTGITPYARFGSWPMWIITLVLGAFTLYCAIRGRSDKH
What is the function of this protein?
Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
What are the official names of this protein?
Apolipoprotein N-acyltransferase, ALP N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CTPJ_MYCTU
Sequence: MAVRELSPARCTSASPLVLARRTKLFALSEMRWAALALGLFSAGLLTQLCGAPQWVRWALFLACYATGGWEPGLAGLQALQRRTLDVDLLMVVAAIGAAAIGQIAEGALLIVIFATSGALEALVTARTADSVRGLMGLAPGTATRVGAGGGEETVNAADLRIGDIVLVRPGERISADATVLAGGSEVDQATVTGEPLPVDKSIGDQVFAGTVNGTGALRIRVDRLARDSVVARIATLVEQASQTKARTQLFIEKVEQRYSIGMVAVTLAVFAVPPLWGETLQRALLRAMTFMIVASPCAVVLATMPPLLAAIANAGRHGVLAKSAIVMEQLGTTTRIAFDKTGTLTRGTPELAGIWVYERRFTDDELLRLAAAAEYPSEHPLGAAIVKAAQSRRIRLPTVGEFTAHPGCRVTARVDGHVIAVGSATALLGTAGAAALEASMITAVDFLQGEGYTVVVVVCDSHPVGLLAITDQLRPEAAAAISAATKLTGAKPVLLTGDNRATADRLGVQVGIDDVRAGLLPDDKVAAVRQLQAGGARLTVVGDGINDAPALAAAHVGIAMGSARSELTLQTADAVVVRDDLTTIPTVIAMSRRARRIVVANLIVAVTFIAGLVVWDLAFTLPLPLGVARHEGSTIIVGLNGLRLLRHTAWRRAAGTAHR
What are the official names of this protein?
Probable cation-transporting P-type ATPase J.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: S26A6_MOUSE
Sequence: MGLPDGSDQGTHQTQALLSAAQEMELQRRDYHVERPLLNQEQLEDLGHWGPAAKTHQWRTWFRCSRARAHSLLLQHVPVLGWLPRYPVREWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPMFGLYSSFYPVFIYFLFGTSRHISVGTFAVMSVMVGSVTESLTADKAFVQGLNATADDARVQVAYTLSFLVGLFQVGLGLVHFGFVVTYLSEPLVRSYTTAASVQVLVSQLKYVFGIKLSSHSGPLSVIYTVLEVCAQLPETVPGTVVTAIVAGVALVLVKLLNEKLHRRLPLPIPGELLTLIGATGISYGVKLNDRFKVDVVGNITTGLIPPVAPKTELFATLVGNAFAIAVVGFAIAISLGKIFALRHGYRVDSNQELVALGLSNLIGGFFQCFPVSCSMSRSLVQESTGGNTQVAGAVSSLFILLIIVKLGELFRDLPKAVLAAVIIVNLKGMMKQFSDICSLWKANRVDLLIWLVTFVATILLNLDIGLAVSIVFSLLLVVVRMQLPHYSVLGQVPDTDIYRDVAEYSGAKEVPGVKVFRSSATLYFANAELYSDSLKEKCGVDVDRLITQKKKRIKKQEMKLKRMKKAKKSQKQDASSKISSVSVNVNTNLEDVKSNDVEGSEAKVHQGEELQDVVSSNQEDAKAPTMTSLKSLGLPQPGFHSLILDLSTLSFVDTVCIKSLKNIFRDFREIEVEVYIAACYSPVVAQLEAGHFFDESITKQHVFASVHDAVTFALSHRKSVPKSPVLATKL
What is the function of this protein?
Mediates electrogenic chloride-bicarbonate exchange with a chloride-bicarbonate stoichiometry of 1:2 (PubMed:12217875, PubMed:23933580).  Also mediates exchange of chloride-formate and chloride-oxalate ions (PubMed:11459928, PubMed:12217875, PubMed:15203903, PubMed:17151144, PubMed:23933580).  Mediates transcellular sulfate absorption (PubMed:12217875).
What are the official names of this protein?
Solute carrier family 26 member 6, Anion exchange transporter, Chloride-formate exchanger, Pendrin-L1, Pendrin-like protein 1, Putative anion transporter-1, Pat-1.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Microsome. Note=Colocalized with CA2 at the surface of the cell membrane in order to form a bicarbonate transport metabolon; colocalization is reduced in phorbol myristate acetate (PMA)-induced cells (By similarity). Localized in sperm membranes. Colocalizes with CFTR at the midpiece of sperm tail. Localizes to the apical membrane brush border of epithelial cells in the proximal tubules of kidney, of enterocytes of the small intestine and of gastric parietal cells in the stomach. May be translocated from the cytosolic surface of the cell membrane to the intracellular space by PKC in phorbol myristate acetate (PMA)-induced cells.
Protein: FMT_HALH5
Sequence: MKIVFMGTPDFSVPVLRRLIEDGYTIAAVVTQPDRPVGRKRVLTPPPVKVEAEKHQIPVLQPEKIRDEAELERLFSFEPDLIVTAAFGQILPNALLEYPKHGCINVHASLLPKYRGGAPIHQAIIDGEKETGITIMYMAEKLDAGDILTQVTVPIADDDHVGSLHNKLSEAGAALLAKTIPPLIKGELQSIPQDDQLATFAPNITREKEEIDWRKEGERIYNQIRGLHPWPVAYTLWNGKPMKIWWAEKVSSPKKEAPGTVIALEENGFLVATGDETALKVTDLQPAGKKRMLARDFLRGAGSQLSVGSVLGGQDGS
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.