PharMolix/UniProtQA huggingface dataset:
Protein: ARNB_PSEA8
Sequence: MSLDFLPFSRPSIGEDEIAAVEQVLRSGWITTGPKNQELEQRFAERLGCRHAVALSSATGALHVTLLALGIGPGDEVITPSLTWVSTANVITLLGATPVFVDVDRDTLMCSAQAVEAAIGPRTRAIVPVHYAGSTLDLEGLRTVAGRHGIALVEDAAHAVGSEYRGRPVGSRGTAIFSFHAIKNLTCAEGAMFVSDDSALAERVRRLKFHGLGVDAYDRLSHGRKPQAEVIEPGFKYNLADLNAALALVQLKRLDALNARRQALAERYLERLAGLPLAPLGLPAHKQRHAWHLFILRIDAEACGLGRDAFMEALKARGIGSGIHFIASHLHHYYRQRQPRLSLPNSEWNSARLCSIPLFPDMRDDDIERVARAIEEILEKRR
What is the function of this protein?
Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase, UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase, UDP-Ara4O aminotransferase, UDP-4-amino-4-deoxy-L-arabinose aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.
Protein: ISPDF_RHOPT
Sequence: MTNSPRTAAIIVAAGRGLRAGAGGPKQYRTLAGRPVIARAMEPFCTHPGVMAVQPVTNPDDTEMFNAAVAGLNFRPAVGGGATRQASVRAGLEALAELKPDIVLIHDAARCFVTPELISRAITAAGATGAALPVVAVTDTIKQVDSSGAVDATPDRASLRIAQTPQAFRFDVILDAHRRAASGGRDDFTDDAAIAEWAGLTVSTFEGDANNMKMTTPEDFAREESRLMAALGDIRTGTGYDVHAFGEGDHVWLCGLKVPHTRGFLAHSDGDVGLHALVDAILGALADGDIGSHFPPTDPQWKGAASDKFLKYAIDRVTARGGRVANLEVTMICERPKIGPLRDAMRQRIAEITGVPVSRVAVKATTSEKLGFTGREEGIAATASATIRLPWGADGLAG
What is the function of this protein?
Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
What are the official names of this protein?
Bifunctional enzyme IspD/IspF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the IspF family.
Protein: FABH_LATSS
Sequence: MAFKIIETASALPANIVTNDDLTAIMETSNEWIESRTGILERRISETENTSDLCLRVAQTLLDKSGIAVSQIKAIIVATMTPDYYTPSTAAIVQGRLGADQAFAFDISAACSGFTYALSAARGYVQTPDDYVLVIGGEVISKMLDWSDRSTAVLFGDGAAGVLLQGTTSDQESWVSEKLITIGTESDQLVSGYAPVKRPNFGQVGQTQVGIDFFKMTGKAIYQFSTRRVPKAIEAAVLEAGLTLDQIDHFLVHQANSRLITKMASMLDQPLTKFPMNLQHYGNTSAASIPLLLAEQVETNQIKRGDLCVLCGFGGGLTIGIQIIRY
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_BART1
Sequence: MAKEATRVRRRERKNISSGVVHINSTFNNTMITITDAQGNAIAWSSAGAQGFKGARKSTPFAAQVAAEDCARKAQEHGMRSLEVEVCGPGAGRESALRALQSVGFVITSIRDVTPIPHNGCRPRKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: SEY1_DICDI
Sequence: MSEEITTNQTVEEEQQTNQPRLSNENIKQEDEEQQVQEQQEQQQQEQQEQIDDQDTQQQEDEFVVLEETKPVEPIRPTPTLQETPQQQKQQTQEQEHEYQDIVQFIDHKGDIVKEDNKNGRTTFLSTLSNRDDFLTKGFDYSVISILGPQSSGKSTLLNLLFNTRFAVMDASTGRKQTTQGVWMGVASTTNNKNETFLILDVEGTDGRERGEDEKAFERKTSLFSLALSSVLIINMWAHDIGRYNAANISLLKTVFELNLQLFQKKRNHKILIFFLIRDHDGVTPLERLKATLMEDITKLWTDLQKPEEFVGTRESDFFDFEFTTLPHKIYSPTAFLGQVEQLKQRFSDSGADSFIPKRKYRNDDIPADGFYQFSYQVWETIKSNRDLDLPSQKEMLALYRCDEFVEQSMTQFTRDIKPIKEHIERGRIQEQFGEKSKRILDQSLSVYDEPAQRYHLETVQKKRQVLTDRILTELKYLFDKQMERLNENTLVFYNSLIKEFTDSNTGSSSGSGNNNNKKRDGSSVLLTAASVGIIPQFSTWSNGIKKKSIEYFEIVANQSIVPGSDWSFENDLEQLKIKIDKELSILKENQLVRLSKLMRDKTFQQELTPLLTKITEQAPNNMWQKIKTYYDDALSSNEKEFRDRLVDFQLDEQKVNELINKFREQLADGLKNKITERAEFLQMRMRKRFEEKFNMDNRNLPRKWTKTDDIASIFQDARQNAEKLIDLFSYLRLDEEDSNVSFFKRLDNDEHEENTMVNSSKIIIPYKDCCLACENFRLTIKSDYMQALSEQNRLTSGGGVPGYMIILLCVLGFNEFISIISSPLLLLLTILLGGVGFVLFKLGLAGPFIDYSSQILVHFISKVKDIVLHVEQLQEQNHNNNNNNNNTPKQKRE
What is the function of this protein?
Probable GTP-binding protein that may be involved in cell development.
What are the official names of this protein?
Protein SEY1 homolog.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: Y541_RUTMC
Sequence: MTTINLTSETLFNFPCDYHIKVLGKDCEALQRTIYSIVERYTDKLHPNQITKKHSSKGNYMSFSIHIIASSRIQLDAINQDLQDCHLVSYVL
What are the official names of this protein?
UPF0250 protein Rmag_0541.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.
Protein: CLC_DICDI
Sequence: MSDPFGEENVEITEEFVEGDINENDLIDGNVEYVDGNGISFETTTFDNSNNNNNNNNHNNNSYNSGFDGDLSSVDGDMKPKETAPAMREYLEKHEKEMQEKKKKSEEKRQKKIAEAKQSLDNFYSEREAKKKTALKNNRDHNKSLETDSTSGNTTHTWESVVSMIDLQAKPNPANKDTSRMREILIRLKNQPIV
What is the function of this protein?
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
What are the official names of this protein?
Clathrin light chain.
What is the protein family that this protein belongs to?
Belongs to the clathrin light chain family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic face of coated pits and vesicles. Localized to punctae scattered within the cytoplasm, along the plasma membrane and concentrated in the perinuclear region.
Protein: EFTS_CAMJJ
Sequence: MAEITAAMVKELRESTGAGMMDCKNALSETNGDFDKAVQLLREKGLGKAAKKADRLAAEGLVSVKVSDDFTSATVSEINSETDFVAKNDQFIALTKDTTAHIQSNSLQSVEELHSSTINGVKFEEYLKSQIATIGENLVVRRFATLKAGANGVVNGYIHTNGRVGVVIAAACDSTEVASKSRDLLRQICMHIAAMRPSYLSYEDLDMTFVENEYKALVAELEKENEERRRLKDPNKPEHKIPQFASRKQLSDAILKEAEEKIKEELKAQGKPEKIWDNIIPGKINSFIADNSQLDSKLTLMGQFYVMDDKKTVEQVIAEKEKEFGGKIKIVEFICFEVGEGLEKKTEDFAAEVAAQL
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP1_POVBO
Sequence: MSRMRKNMNPPKKGLKGQPSPVPKLIIKGGIEVLGLRTGPDSTTTIELFLNPRMGQSTESEYYGFSDNQRGSTSRTDEDLISAELPRYSLGVVQLPLLNEKLTDDVLLMWEAVSCKTEVVGVNTLTTCHGYKKRYSPSAGQGSAMPIEGINYHFFAVGGEPLEIQFICEDFKAPYHPTETIVPPKDKLSNKSQVLDPTLKGILDKDGVYPVECWCPDPSKNENTRYFGTYTGGVSTPPVLQFTNTVTTILLDENGVGPLCKADKLYITAADICGFLTQPNDQQQFRGLPRYMSVTLRKRLVKNPYPIASILTSLFTNSLPPVTSQEMDKQVEEVRIYQGVEGLPGDPDMVRYINKFGQEETCIPK
What is the function of this protein?
Forms an icosahedral capsid with a T=7 symmetry and a 40 nm diameter.  The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with VP2 or VP3 proteins.  Interacts with sialic acids on the cell surface to provide virion attachment to target cell.  Once attached, the virion is internalized by endocytosis and traffics to the endoplasmic reticulum.  Inside the endoplasmic reticulum, the protein folding machinery isomerizes VP1 interpentamer disulfide bonds, thereby triggering initial uncoating.  Next, the virion uses the endoplasmic reticulum-associated degradation machinery to probably translocate in the cytosol before reaching the nucleus.  Nuclear entry of the viral DNA involves the selective exposure and importin recognition of VP2/Vp3 nuclear localization signal.  In late phase of infection, neo-synthesized VP1 encapsulates replicated genomic DNA in the nucleus, and participates in rearranging nucleosomes around the viral DNA.
What are the official names of this protein?
Major capsid protein VP1, Major structural protein VP1.
What is the protein family that this protein belongs to?
Belongs to the polyomaviruses coat protein VP1 family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: EX7L_CAUVN
Sequence: MSDLPPTDSNAPPYSVSELAFALKRTLEDRYGFVRLRGELSKVTHHSNGHVYLTIKDDKSAIDGVVWKGNVRGLGVRPEHGLEVIVTGKITTYPAGSRYQIVIDSMEAAGVGALLAQLERLKAKLAAEGLFAPERKRPLPSMPAVVGVITSPTGAVIRDILHRIRDRWPCQVLVWPCVVQGDAAAGQVSAAIRGFNAIQPGGPVPRPDVLIVARGGGSVEDLWAFNDEGLARTVAEGTIPLISAVGHETDTTLIDFVSDRRAPTPTAAAEMATPVLAELRALISDLDRRLNRCGARTIEERRTRLVSAARGLPRPNDLLALAQQRFDIASGRLDAALDRNTTVHAQSLLKVTARLTPEALGRQRAVKAERLADLSRRLDLAARRAPDRVAQHARLPALWDRLNAAGQRRLQRDADRLENLEKLRQSLNPERPLELGFALVRKGDGTLARSAADLVSGERVNLKFKSGDRDAVIDGEGGPAPAPTAPAPKPRPKPAAPPAGQGDLF
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_BACC0
Sequence: MDKRISIAIDGPAAAGKSTVAKVVAKKLSYVYIDTGAMYRTITYAALEQKVDIENEEQLMEVVKNVKIEFQQGENTQLVFLNGQDVSEVIRTPEVTNRVSIVAKHRLVREEMVRRQQELAEKGGVVMDGRDIGTHVLPDAEVKIFMLASVEERAERRHLENMNKGFDSNLEQLKEEIAQRDKLDSEREVSPLKKADDALELDTTSLSIEEVVQKIMGIVSGVFAK
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y345_BEII9
Sequence: MAGHSQFKNIMHKKGKQDAIRSKLFSKLAREITVAAKLGLPDPAMNARLRAAVLAARAENMPKDNIERAIKKASAADGENYDEVRYEGYAPGGVALIVEALTDNRNRTAGEVRSYFTKSGGSLAETGAVSFMFDHVGLIEFPASVASEEAMLEAAIEAGAEDVQSNEETHEIITSLESLRDVAQALETKFGEPRKASLIWKAQNAIAVDDEAGEKILRLVNLLEENDDVQNVYANFEVSDTLLAKLGD
What are the official names of this protein?
Probable transcriptional regulatory protein Bind_0345.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAPR_KLULA
Sequence: MATYQTELDLFKNEVEQKQPNDFLQFAANYFTKRLEQQRTFVRNQESLALSKGIVLFPSTSKHDSVAASSASLSHGSSKANASQSGISSSGVDEDVLFKSPFVDRGPHSTHIVDHLDSTHSNTTASPAKASGGDAPGIFKGNFNVGTESQRKVNSSVDPMAPEPTATTHSFPRRSVVNPKPLPINFNAQRRTSVSGETLQPDHLDDWKPENFQEKSPEQVSRLEKAVGKNFLFNKLDSDSKKLVINSLEEKSIPQGKEIIKQGDEGDYFYIVEDGTVEFYVNNQKVNTSGPGSSFGELALMYNSPRAATVIASTDCILWALDRLTFRRILLGGSFKKRILYDDLLKNIPILKSLSTYDRAKLADALDTEYYEAGQTIIKEGDTGENFYFIEYGEADVSQEGKGVITKLGKGDYFGEVALLNDLPRQATVTATARTKVATLGKSGFQRLLGPVVDVLKLNDPTRSKH
What are the official names of this protein?
cAMP-dependent protein kinase regulatory subunit, PKA regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the cAMP-dependent kinase regulatory chain family.
Protein: NP1L5_MOUSE
Sequence: MADPEKQGPAESRAEDEVMEGAQGGEDAATGDSAAAPAAEEPQAPAENAPKPKKDFMESLPNSVKCRVLALKKLQKRCDKIEAKFDKEFQALEKKYNDIYKPLLAKIQELTGEMEGCAWTLEGEDDEDDEEEDDEEEEEEEEAAAGATGGPNFAKK
What are the official names of this protein?
Nucleosome assembly protein 1-like 5.
What is the protein family that this protein belongs to?
Belongs to the nucleosome assembly protein (NAP) family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YBEY_PSEA8
Sequence: MPLELDLQVASAAPDLPSEAQFRAWCELALRQRPESELTIRLVDEAEGLELNSTYRHKDYATNVLSFLADVPDELLDIPLLGDLVICAPVVAREALEQRKPLQAHWAHLVIHGCLHLLGYDHIDDAEAEEMETLERELLAELGHPDPYACDDEEPPSKEK
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1495_BACP2
Sequence: MTLEKTTRMNYLFDFYQSLLTAKQKSYMSLYYLDDFSLGEIADEYEVSRQAVYDNIKRTEAMLEQYEEKLLLFKKFKERKELLKKMRELVADSAQTEEAEALIESLEKLD
What is the function of this protein?
Might take part in the signal recognition particle (SRP) pathway.  This is inferred from the conservation of its genetic proximity to ftsY/ffh.  May be a regulatory protein.
What are the official names of this protein?
UPF0122 protein BPUM_1495.
What is the protein family that this protein belongs to?
Belongs to the UPF0122 family.
Protein: NDHK_PANGI
Sequence: MNSIEFPLLDRTTQNSVISTTSNDLSNWSRLSSLWPLLYGTSCCFIEFASLIGSRFDFDRYGLVPRSSPRQADLILTAGTVTMKMAPSLVRLYEQMPEPKYVIAMGACTISGGMFSTDSYSTVRGVDKLIPVDVYLPGCPPKPEAVIDAITKLRKKISREIYEDRIKSQRENRCFTTNHKFQVGRSIHTGNYDRGFLYQPPFTSEIPSETFFKYKSSVSSHELVN
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit K, chloroplastic, NAD(P)H dehydrogenase subunit K, NADH-plastoquinone oxidoreductase subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: FIBR_EISFE
Sequence: VIGGTNASPGEIPWQLSQQRQSGSW
What is the function of this protein?
Cleaves the carboxyl side of basic amino acids, small neutral amino acids, and Met residue.  It is also a plasminogen activator.
What are the official names of this protein?
Fibrinolytic enzyme large subunit.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
Protein: STUA_USTMA
Sequence: MSTASPLHHGHGNGSYANSPAPTGVTGRDAGVAAAAVADSAVRSGSVPASASGSAPGSASGSMYGEAHTQHHTGHHHYSAHHTHSHGALTSPVNGGHSSSWSPYGYPAAPVYGGSPSPYGHNAYSQYASGYGYANGTAHHVATAPTTPSATSTAYHTGVNGMMMHHGQHAGYGYSSHHLGSHTPTHTHTHSSAYFMNGDGAHSHLNSSAHLTSPSYTTAPQYSTQLPLAGRHRVTTTLWEDEGTLCFQVDARGVCVARRHDNNMINGTKLLNVCGMSRGKRDGILKNEKERIVVKVGAMHLKGVWISFARAKQLAEQNGIADALYPLFEPNIQSFLYHPDNYPRTAAVIAAAQERQAQRQRAPGGQPSPGANGTSQAPPLMRANTTPSNGDTSTFSSGLSSLGSWTGSHDQGHASAPTTAQPSPSSMHNGATQMHMSLSNHGTASPTYAQSQQQQQQQQQQQQQQQQQQQQQQQQAYPMTAAQQLARPSVGDRRQSAPISLNNSVGHAENPYGATNLGGAANGGLVNGARKVSGLKRSWNDADDLNGSAAASPTERDMQRSGSGGSNGLKLDGDDLHSPDSSDDRLAKKTRGMPQRGGGATTAMPSMSTNMLMGVGNGSGIHHE
What is the function of this protein?
Transcription factor that regulates asexual reproduction (PubMed:25208341).  Binds the StuA-response elements (StRE) with the consensus sequence 5'-(A/T)CGCG(T/A)N(A/C)-3' at the promoters of target genes (By similarity).  Regulates dimorphism, virulence, and the sporulation program (PubMed:20064064).  Required for mating, gall induction, and sporogenesis in maize tissue (PubMed:20064064).  Regulates expression of the filament-down-regulated gene UM00205 and the teliospore-specific gene ssp1 (PubMed:20064064).
What are the official names of this protein?
Cell pattern formation-associated protein ust1, Stunted protein A.
What is the protein family that this protein belongs to?
Belongs to the EFG1/PHD1/stuA family.
What are the subcellular locations of this protein?
Nucleus. Note=Accumulates in the nucleus during teliospore germination (PubMed:25208341).
Protein: TRPD1_RALSO
Sequence: MTISPQDALTRCIEHREIFHDEMLHLMRLIMRGEMSPVIASALIMGLRVKKETIGEIAAAATVMREFATTVDVPAAILDHFVDIVGTGGDGANTFNISTASMFVAAAAGARIAKHGGRGVSSKSGSADVLEALGVNIMLTPEQVAQSIEAVGIGFMFAPNHHPAMKNVAPIRKELGVRTLFNILGPLTNPAGAPNILMGVFHPDLVGIQVRVMQRLGARHAVVVYGKDGMDEVSLGAATVVGELKDGEVREYEIHPEDYGLQMVSNRGLKVADAEESKAMLLGALENVPGTPREIVTLNAGAALYAANLAGSIGDGITLAREAIASGAARAKVDELVRVTNQFKK
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: RLME_FRATH
Sequence: MSKGSSTKKWLHEHTSDYYVIQANKLGYRSRASFKILEIQDKYQLFKPNMFVVDLGASPGGWSEQVIKYIGKNGKLIALDLLEMAPIAGVEFIQGDFSSDETYQKLNTLVNNQKIDCVISDMAPNLSGNKTSDQAKSIYLLELALDFANTNLNKNGSFVAKVFQGQGSDEYLKLVRESFNKVIQFKPKSSRAKSREFYVIATEFKG
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUB7_ARATH
Sequence: MDVTELEENLFAASDAKLHGDMCKELSGVLCKVLSIFPSLEGARPRSKSGIQALCSLHIALEKAKNILQHCSECSKLYLAITGDAVLLKFEKAKIALIDGLKRVEDIVPSSIGSQILEIVGELENTRFMLDPSEKEVGDQIIALLQQGKKFDNCNDNTELEIFHRAATRLSITSSRVALAERRALKKLIDRARAEEDKRKESIVAYLLHLMRKCSKLFRSEILDENDSPGSYPCSPNEDHGSVHGFGRQLSRFGSLNDKPMNSINSGQMPVPPEELRCPISLQLMCDPVIIASGQTYERVCIEKWFSDGHNTCPKTQQQLPHISLTPNNCVKGLIASWCEQNGTQIPSGPPESQDLDYWRLALSDSESTKSQSVNSIGSYKLKGVKIVPLEENGTTVVERQNTEESFVSDDDDEEDSDINVLERYQDLLAVLNEEEGLEKKCKVVEKIRLLLKDDEEARIFMGANGFVEALLRFLGSAVDDNNAAAQDSGAMALFNLAVNNNRNKELMLTSGVIRLLEKMISSAESHGSATALYLNLSCLDEAKSVIGSSQAVPFLVQLLQKEIETQCKLDALHALYNLSTYSPNIPALLSSNIIKSLQGLLASTGENLWIEKSLAVLLNLASSQEGKDEAVSSQGMISSLATVLDMGDTTEQEQAVSCLLILCNGRESCIQMVLQEGVIPSLVSISVNGTPRGREKSQKLLMLFREERQQRDQPSSNRDEPPQKEPARKSLSAPLSVHGSTPASASVQDYEPRVLSKSMSRRKSMARPFSFFWKKSYSVRE
What is the function of this protein?
Functions as an E3 ubiquitin ligase.
What are the official names of this protein?
U-box domain-containing protein 7, Plant U-box protein 7, RING-type E3 ubiquitin transferase PUB7.
Protein: C2D1A_HUMAN
Sequence: MHKRKGPPGPPGRGAAAARQLGLLVDLSPDGLMIPEDGANDEELEAEFLALVGGQPPALEKLKGKGPLPMEAIEKMASLCMRDPDEDEEEGTDEDDLEADDDLLAELNEVLGEEQKASETPPPVAQPKPEAPHPGLETTLQERLALYQTAIESARQAGDSAKMRRYDRGLKTLENLLASIRKGNAIDEADIPPPVAIGKGPASTPTYSPAPTQPAPRIASAPEPRVTLEGPSATAPASSPGLAKPQMPPGPCSPGPLAQLQSRQRDYKLAALHAKQQGDTTAAARHFRVAKSFDAVLEALSRGEPVDLSCLPPPPDQLPPDPPSPPSQPPTPATAPSTTEVPPPPRTLLEALEQRMERYQVAAAQAKSKGDQRKARMHERIVKQYQDAIRAHKAGRAVDVAELPVPPGFPPIQGLEATKPTQQSLVGVLETAMKLANQDEGPEDEEDEVPKKQNSPVAPTAQPKAPPSRTPQSGSAPTAKAPPKATSTRAQQQLAFLEGRKKQLLQAALRAKQKNDVEGAKMHLRQAKGLEPMLEASRNGLPVDITKVPPAPVNKDDFALVQRPGPGLSQEAARRYGELTKLIRQQHEMCLNHSNQFTQLGNITETTKFEKLAEDCKRSMDILKQAFVRGLPTPTARFEQRTFSVIKIFPDLSSNDMLLFIVKGINLPTPPGLSPGDLDVFVRFDFPYPNVEEAQKDKTSVIKNTDSPEFKEQFKLCINRSHRGFRRAIQTKGIKFEVVHKGGLFKTDRVLGTAQLKLDALEIACEVREILEVLDGRRPTGGRLEVMVRIREPLTAQQLETTTERWLVIDPVPAAVPTQVAGPKGKAPPVPAPARESGNRSARPLHSLSVLAFDQERLERKILALRQARRPVPPEVAQQYQDIMQRSQWQRAQLEQGGVGIRREYAAQLERQLQFYTEAARRLGNDGSRDAAKEALYRRNLVESELQRLRR
What is the function of this protein?
Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells.  The combination of calcium and ATP specifically inactivates the binding with FRE.  May play a role in the altered regulation of HTR1A associated with anxiety and major depression.  Mediates HDAC-independent repression of HTR1A promoter in neuronal cell.  Performs essential function in controlling functional maturation of synapses (By similarity).  Plays distinct roles depending on its localization.  When cytoplasmic, acts as a scaffold protein in the PI3K/PDK1/AKT pathway.  Repressor of HTR1A when nuclear.  In the centrosome, regulates spindle pole localization of the cohesin subunit SCC1/RAD21, thereby mediating centriole cohesion during mitosis.
What are the official names of this protein?
Coiled-coil and C2 domain-containing protein 1A, Akt kinase-interacting protein 1, Five prime repressor element under dual repression-binding protein 1, FRE under dual repression-binding protein 1, Freud-1, Putative NF-kappa-B-activating protein 023N.
What is the protein family that this protein belongs to?
Belongs to the CC2D1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: YIHY_ECOL6
Sequence: MLKTIQDKARHRTRPLWAWLKLLWQRIDEDNMTTLAGNLAYVSLLSLVPLVAVVFALFAAFPMFSDVSIQLRHFIFANFLPATGDVIQRYIEQFVANSNKMTAVGACGLIVTALLLMYSIDSALNTIWRSKRARPKIYSFAVYWMILTLGPLLAGASLAISSYLLSLRWASDLNTVIDNVLRIFPLLLSWISFWLLYSIVPTIRVPNRDAIVGAFVAALLFEAGKKGFALYITMFPSYQLIYGVLAVIPILFVWVYWTWCIVLLGAEITVTLGEYRKLKQAAEQEEDDEP
What are the official names of this protein?
UPF0761 membrane protein YihY.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: 2A5E_RABIT
Sequence: MSSAPTTPPSVDKVDGFSRKSVRKARQKRSQSSSQFRSQGKPIELTPLPLLKDVPSSEQPELFLKKLQQCCVIFDFMDTLSDLKMKEYKRSTLNELVDYITISRGCLTEQTYPEVVRMVSCNIFRTLPPSDSNEFDPEEDEPTLEASWPHLQLVYEFFIRFLESQ
What is the function of this protein?
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform, PP2A B subunit isoform B'-delta, PP2A B subunit isoform B'-epsilon, PP2A B subunit isoform B56-epsilon, PP2A B subunit isoform PR61-epsilon, PP2A B subunit isoform R5-epsilon.
What is the protein family that this protein belongs to?
Belongs to the phosphatase 2A regulatory subunit B56 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_RHORT
Sequence: MKLLVAAVGRWRGGPERALFDHYVGRLKGGLAVIEVEERRPLPVAERKAREAELLLAQLPPGAFVVALDEHGEAWGSERLARELDQRRLEARPAAVFAIGGADGHGEALLARADRKLALGVMTWPHMLVRGLIAEQLYRAQCISGGHPYHRS
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YG4U_YEAST
Sequence: MLIVIFHKAIFSNSSLASSTLASSLLISFSSFLFISSVCLFTSSSFFADSVTCSFSTCSFSSTFGCFSSSFLSLSCLMSTLSALISCSACPRLSVFTVVVSASLGSVFTILTDS
What are the official names of this protein?
Putative uncharacterized protein YGR228W.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.