PharMolix/UniProtQA huggingface dataset:
Protein: NPC1_MOUSE
Sequence: MGAHHPALGLLLLLLCPAQVFSQSCVWYGECGIATGDKRYNCKYSGPPKPLPKDGYDLVQELCPGLFFDNVSLCCDIQQLQTLKSNLQLPLQFLSRCPSCFYNLMTLFCELTCSPHQSQFLNVTATEDYFDPKTQENKTNVKELEYFVGQSFANAMYNACRDVEAPSSNEKALGLLCGRDARACNATNWIEYMFNKDNGQAPFTIIPVFSDLSILGMEPMRNATKGCNESVDEVTGPCSCQDCSIVCGPKPQPPPPPMPWRIWGLDAMYVIMWVTYVAFLFVFFGALLAVWCHRRRYFVSEYTPIDSNIAFSVNSSDKGEASCCDPLGAAFDDCLRRMFTKWGAFCVRNPTCIIFFSLAFITVCSSGLVFVQVTTNPVELWSAPHSQARLEKEYFDKHFGPFFRTEQLIIQAPNTSVHIYEPYPAGADVPFGPPLNKEILHQVLDLQIAIESITASYNNETVTLQDICVAPLSPYNKNCTIMSVLNYFQNSHAVLDSQVGDDFYIYADYHTHFLYCVRAPASLNDTSLLHGPCLGTFGGPVFPWLVLGGYDDQNYNNATALVITFPVNNYYNDTERLQRAWAWEKEFISFVKNYKNPNLTISFTAERSIEDELNRESNSDVFTVIISYVVMFLYISLALGHIQSCSRLLVDSKISLGIAGILIVLSSVACSLGIFSYMGMPLTLIVIEVIPFLVLAVGVDNIFILVQTYQRDERLQEETLDQQLGRILGEVAPTMFLSSFSETSAFFFGALSSMPAVHTFSLFAGMAVLIDFLLQITCFVSLLGLDIKRQEKNHLDILCCVRGADDGQGSHASESYLFRFFKNYFAPLLLKDWLRPIVVAVFVGVLSFSVAVVNKVDIGLDQSLSMPNDSYVIDYFKSLAQYLHSGPPVYFVLEEGYNYSSRKGQNMVCGGMGCDNDSLVQQIFNAAELDTYTRVGFAPSSWIDDYFDWVSPQSSCCRLYNVTHQFCNASVMDPTCVRCRPLTPEGKQRPQGKEFMKFLPMFLSDNPNPKCGKGGHAAYGSAVNIVGDDTYIGATYFMTYHTILKTSADYTDAMKKARLIASNITETMRSKGSDYRVFPYSVFYVFYEQYLTIIDDTIFNLSVSLGSIFLVTLVVLGCELWSAVIMCITIAMILVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTMSTKGSRVSRAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQIFEIFYFRMYLAMVLLGATHGLIFLPVLLSYIGPSVNKAKRHTTYERYRGTERERLLNF
What is the function of this protein?
Intracellular cholesterol transporter which acts in concert with NPC2 and plays an important role in the egress of cholesterol from the endosomal/lysosomal compartment (PubMed:21896731, PubMed:22048958, PubMed:27551080).  Unesterified cholesterol that has been released from LDLs in the lumen of the late endosomes/lysosomes is transferred by NPC2 to the cholesterol-binding pocket in the N-terminal domain of NPC1.  Cholesterol binds to NPC1 with the hydroxyl group buried in the binding pocket (By similarity).  May play a role in vesicular trafficking in glia, a process that may be crucial for maintaining the structural and functional integrity of nerve terminals (Probable).  Inhibits cholesterol-mediated mTORC1 activation throught its interaction with SLC38A9 (By similarity).
What are the official names of this protein?
NPC intracellular cholesterol transporter 1, Niemann-Pick C1 protein.
What is the protein family that this protein belongs to?
Belongs to the patched family.
What are the subcellular locations of this protein?
Late endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein.
Protein: RL14_SYNPW
Sequence: MIQQESFLTVADNSGAKRIQCIRVLGTNRRYAHVGDVIVAAVKDAMPNMGVKKSDVVKAVVVRTKATLRRDTGNSIRFDDNAAVIINDDKNPKGTRVFGPVARELRERNFTKIVSLAPEVI
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: ANXA4_MOUSE
Sequence: MEAKGGTVKAASGFNATEDAQTLRKAMKGLGTDEDAIIGILAYRNTAQRQEIRSAYKSTIGRDLIEDLKSELSSNFEQVILGLMTPTVLYDVQELRRAMKGAGTDEGCLIEILASRTPEEIRRINQTYQQQYGRSLEEDICSDTSFMFQRVLVSLSAAGRDEGNYLDDALMKQDAQELYEAGEKRWGTDEVKFLSILCSRNRNHLLHVFDEYKRISQKDIEQSIKSETSGSFEDALLAIVKCMRSKPSYFAERLYKSMKGLGTDDNTLIRVMVSRAEIDMLDIRASFKRLYGKSLYSFIKGDTSGDYRKVLLVLCGGDD
What is the function of this protein?
Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis.
What are the official names of this protein?
Annexin A4, Annexin IV, Annexin-4.
What is the protein family that this protein belongs to?
Belongs to the annexin family.
What are the subcellular locations of this protein?
Zymogen granule membrane; Peripheral membrane protein.
Protein: RL34_LIGS1
Sequence: MKRTYQPKKRHRQRVHGFRKRMSTSNGRNVLARRRRKGRKVLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: XPT1_CRYNB
Sequence: MPPTALPPLRPPAQPYDSYSSSLSPSSPRFHPASAPHGRRAPSPSRLESLLDAPHAPARSPSRKIRSALSRHIRPHLTPRTLTPLLLWTLALWLVHHFLFPFSSPLAALSRPKAEQHFLSTTFPPPPQRLGDDRLDSVDPRWRAFHPLPPPEPPFPRLRPTRFLPPQCLEQWFADGETLCGAKEMGEEETLDATWLWVNGSDHRWRDSMAEWREKENVNSPERHFREQNELVHSMRSVLDALPGHLRTFHLILADYPFNYPEDLDLVPPSIIPDLEVAASKGGQGRRHPRELARAPASVSNLTERLTPESISPSLARHLQSEWRILQTPTWLDFSRRDPSDPSHPFHPYSVSKAGEMRQHYAEASYPTLRYASHWEVFHIPSVDRDGREELMGEREWRENEWKKKALPSFNSMAIESRIGWLPGLADAIIALNDDFFLLRPHAVSDFHSPLYGSVIRFEHSYNQQVKPDVEKNHINDPGEMGGLYHANALLSRRFPHRLRPYFAHVPKVITRGLHHEASLMFQEALTLSSTRKFREMKIGEGDVQMQWLLTSLRVERWREALLWTWVVANMGTLSGSHDRWDSDTRSAIKHLFGFTEDDDDVVKIEVHRGERWTLEPGRMQKVFHQAGWEAPKATEFLFSSMDGIMPPLLRSGEDPSQNDRCIIDLNRCFGVFWTRQEDVLSADMMKRLTFQYPECGDCMIMALVTASGTLGLNAFFPPKETTITAPELGPGDAYPKYLPPPHLPLTPTWHEADYSLSNILSTTALPGEQVDIRQYCMRLLSRYLYLDAKSVSHFHMMKSAEHAKRVFKMIQDNPKVSILGMNDDIESDYDEVKRLMNEWFEMRWPRKAVWERDWDPVKDRYHD
What is the function of this protein?
Xylosylphosphotransferase that is specific for UDP-xylose as a donor and mannose as an acceptor to form a xylose-alpha-1-phosphate-6-mannose linkage.  Functions in the O-glycosylation of proteins en route through the secretory pathway (By similarity).
What are the official names of this protein?
3-O-alpha-D-mannopyranosyl-alpha-D-mannopyranose xylosylphosphotransferase, Xylosylphosphotransferase 1.
What is the protein family that this protein belongs to?
Belongs to the XPT1 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type I membrane protein.
Protein: ATPA_RHOOB
Sequence: MAELTISSDEIRSAIENYTASYSPEASREEVGVVTDTSDGIAHVSGLPSAMANELLEFPGGILGVALNLDATEIGAVILGDYENIQEGQEVKRTGDVLSVPVGDAFLGRVINPLGQPIDGLGEIASDETRALELQAASVLERQPVEEPLQTGIKAIDAMTPIGRGQRQLVIGDRKTGKTAVCIDAILNQKANWETGDEKQQVRCIYVAIGQKGSTIAGVKAALEEQGAMEYTTIVAAPASDSAGFKWLAPYTGSAIGQHWMYQGKHVLVVFDDLTKQAEAYRAISLLLRRPPGREAYPGDVFYLHSRLLERSAKLSDALGGGSLTALPIIETKANDVSAYIPTNVISITDGQVFLESDLFNKGVRPAINVGISVSRVGGAAQTKGMKKVSGSLRLELAQFRELEAFSAFASDLDAASKAQLERGARLVELLKQDQYSPIPVEDQIVSIYLAGEGVFDSVPVGDVRRFEAELLDELHRTASGVYESIKGGKALDADNAKALVEATDKFKETFLASDGSRVVNEAEAEALDAGEVGHEQINVKRTTVSK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PROFN_OLEEU
Sequence: MSWQAYVDDHLMCDIEGHEGHRLTAAAIVGHDGSVWAQSATFPQFKPEEMNGIMTDFNEPGHLAPTGLHLGGTKYMVIQGEAGAVIRGKKGSGGITIKKTGQALVFGIYEEPVTPGQCNMVVERLGDYLLEQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity).
What are the official names of this protein?
Profilin-1, Pollen allergen Ole e 2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: PYRE_NEIM0
Sequence: MTDFRQDFLKFSLAQNVLKFGEFTTKAGRRSPYFFNAGLFNDGASTLQLAKFYAQSIIESGIRFDMLFGPAYKGIILAAATAMMLAEKGVNVPFAYNRKEAKDHGEGGVLVGAPLKGRVLIIDDVISAGTSVRESIKLIEAEGATPAGVAIALDRMEKGTGELSAVQEVEKQYGLPVAPIASLNDLFILLQNNPEFGQFLEPVRAYRRQYGVE
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: NAGB_PORGI
Sequence: MRLIIEPDYDKLSKWAADYVIERIHKAAPTAEKPFVLGLPTGSSPIGMYRELVKACKEGCISFRHVITFNMDEYVGLAIEHPESYHSFMHRHLFDHIDILPQNIHILNGNAPDLTAECDAYERAIEAAGGIDLFIGGIGPDGHIAFNEPGSSLTSRTRIKTLTTDTVLANSRFFDNDTNQVPKRALTVGVGTIMDAREVMILVNGHTKARALREAVEGAVSQMWTITALQLHRQSIIVCDEAACVELKVGTYNYFKDIERNNL
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: EFTU_LISMO
Sequence: MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLAKKGYADAQAYDQIDGAPEERERGITISTAHVEYQTDSRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLSRQVGVPYIVVFMNKCDMVDDEELLELVEMEIRDLLTEYEFPGDDIPVIKGSALKALQGEADWEAKIDELMEAVDSYIPTPERDTDKPFMMPVEDVFSITGRGTVATGRVERGQVKVGDEVEVIGIEEESKKVVVTGVEMFRKLLDYAEAGDNIGALLRGVAREDIQRGQVLAKPGSITPHTNFKAETYVLTKEEGGRHTPFFNNYRPQFYFRTTDVTGIVTLPEGTEMVMPGDNIELAVELIAPIAIEDGTKFSIREGGRTVGAGVVSNISK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Secreted, cell wall.
Protein: YL682_MIMIV
Sequence: MGNYISFKKEFGLILVGAIIFTASYLWKDLLLEIEEKYFPKGYGLMWRSIYTILVTVILVLVAIHLKNQFGLVNKDSKDPKDKSIEFDDSPIRDGSSGTPDNSNEPTDLSVETS
What are the official names of this protein?
Uncharacterized protein L682.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RPBCL_ARATH
Sequence: MDLQQSETDDKQPEQLVIYVCGDCGQENILKRGDVFQCRDCGFRILYKKRILDKKETRIGV
What are the official names of this protein?
DNA-directed RNA polymerase subunit 12-like protein.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: OR42B_DROME
Sequence: MVFELIRPAPLTEQKRSRDGCIYLYRAMKFIGWLPPKQGVLRYVYLTWTLMTFVWCTTYLPLGFLGSYMTQIKSFSPGEFLTSLQVCINAYGSSVKVAITYSMLWRLIKAKNILDQLDLRCTAMEEREKIHLVVARSNHAFLIFTFVYCGYAGSTYLSSVLSGRPPWQLYNPFIDWHDGTLKLWVASTLEYMVMSGAVLQDQLSDSYPLIYTLILRAHLDMLRERIRRLRSDENLSEAESYEELVKCVMDHKLILRYCAIIKPVIQGTIFTQFLLIGLVLGFTLINVFFFSDIWTGIASFMFVITILLQTFPFCYTCNLIMEDCESLTHAIFQSNWVDASRRYKTTLLYFLQNVQQPIVFIAGGIFQISMSSNISVAKFAFSVITITKQMNIADKFKTD
What is the function of this protein?
Odorant receptor which mediates acceptance or avoidance behavior, depending on its substrates.  The odorant receptor repertoire encodes a large collection of odor stimuli that vary widely in identity, intensity, and duration.  May form a complex with Orco to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability.  Involved in the behavioral responses to ethyl acetate and pentyl acetate.
What are the official names of this protein?
Odorant receptor 42b.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Heteromeric odorant receptor channel (TC 1.A.69) family. Or2a subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MUTS_CLOK1
Sequence: MGLTPMMRQYMEIKENYKDCILFFRLGDFYEMFFDDAKIAAAELELVLTARECGLKEKAPMCGIPYHAAKSYIGRMVNKGYKIAICEQLEDPAQSKGIVKRGIIKVITPGTYMDSYFLDENENNYIMCLYINNNEGSNCALCFADISTGEFNCTDTPFNLSVILDEICKFNPREIIIQEDIDSNILQGIVEVFNETFSRVDECYFQKGEEVLREQFKDLNLREYTPEIIKCGGALVKYIKHTQKTNLSHINKFQYYNIVDYLTIDINSKRNLEIVESLRESKKKGSLLGVIDKTNTSMGGRQLRKWIEQPLIDRNKIMERLDSVEEILNNICYHEDLKEALKNIYDIERLAGKISSKSVNAKELNSLKSSIEKIPDIKVILSNFETSLLKNMYKNLDELKDIYMLLDKAILDNPSVSLKEGNLIKEGYDSEIDRLKEAKVKGKDWIASLESSERELTKIKSLKIGYNKVFGYYIEVTKSNLNLVPEHRYIRKQTLSNAERYITPELKEMEDKILGAEEKLIYLEYNAFVEVRDKVEKEVTRIQNSARIISEVDCLTSLARAALENNYCKPEITLSDRVYIEEGRHPVVENMLSTGEFVSNDTDIDTGENQLLLITGPNMAGKSTYMRQVALVTIMAQIGSFVPAKSASISICDKIFTRIGASDDLASGKSTFMVEMWEVSNILKNATNKSLILLDEVGRGTSTYDGLSIAWSVIEYICRESKLRCKTLFATHYHELTKLEGKIKGVKNYCVSVKEVENNIVFLRKIIRGGADQSYGIEVAKLAGLPEEVLKRAREILNSLETEKTEESMEGTNLPKKKKEEKTSSQGEQLKFLDIEKENLINEIRDIDILNMTPMEGFNKLYDIIKKVKSI
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: PNPP_SCHPO
Sequence: MAKKLSSPKEYKEFIDKFDVFLFDCDGVLWSGSKPIPGVTDTMKLLRSLGKQIIFVSNNSTKSRETYMNKINEHGIAAKLEEIYPSAYSSATYVKKVLKLPADKKVFVLGEAGIEDELDRVGVAHIGGTDPSLRRALASEDVEKIGPDPSVGAVLCGMDMHVTYLKYCMAFQYLQDPNCAFLLTNQDSTFPTNGKFLPGSGAISYPLIFSTGRQPKILGKPYDEMMEAIIANVNFDRKKACFVGDRLNTDIQFAKNSNLGGSLLVLTGVSKEEEILEKDAPVVPDYYVESLAKLAETA
What are the official names of this protein?
4-nitrophenylphosphatase, PNPPase.
Protein: FIBER_BPSFV
Sequence: MTDIITNVVIGMPSQLFTMARSFKAVANGKIYIGKIDTDPVNPENQIQVYVENEDGSHVPASQPIVINAAGYPVYNGQIVKFVTEQGHSMAVYDAYGSQQFYFQNVLKYDPDQFGPDLIEQLAQSGKYSQDNTKGDAMIGVKQPLPKAVLRTQHDKNKEAISILDFGVIDDGVTDNYQAIQNAIDAVASLPSGGELFIPASNQAVGYIVGSTLLIPGGVNIRGVGKASQLRAKSGLTGSVLRLSYDSDTIGRYLRNIRVTGNNTCNGIDTNITAEDSVIRQVYGWVFDNVMVNEVETAYLMQGLWHSKFIACQAGTCRVGLHFLGQCVSVSVSSCHFSRGNYSADESFGIRIQPQTYAWSSEAVRSEAIILDSETMCIGFKNAVYVHDCLDLHMEQLDLDYCGSTGVVIENVNGGFSFSNSWIAADADGTEQFTGIYFRTPTSTQSHKIVSGVHINTANKNTAANNQSIAIEQSAIFVFVSGCTLTGDEWAVNIVDINECVSFDKCIFNKPLRYLRSGGVSVTDCYLAGITEVQKPEGRYNTYRGCSGVPSVNGIINVPVAVGATSGSAAIPNPGNLTYRVRSLFGDPASSGDKVSVSGVTINVTRPSPVGVALPSMVEYLAI
What is the function of this protein?
Non-covalently bound to the neck of the phage capsid and mediating attachment of the viral particle to host cell-surface polysaccharide.  It displays endorhamnosidase enzymatic activity, hydrolyzing the alpha-1,3-O-glycosidic linkage between rhamnose and galactose of the O-antigen polysaccharide.
What are the official names of this protein?
Tail spike protein, TSP, Endo-1,3-alpha-L-rhamnosidase, Endorhamnosidase.
What is the protein family that this protein belongs to?
Belongs to the P22likevirus tail fiber protein family.
What are the subcellular locations of this protein?
Virion.
Protein: MBF1_NEUCR
Sequence: MSAWDTDAVKIGKNVSRGGAGPRETVVRGKSALNAAQRSGNIIATEKKYAAGNTASKPGVEGQRLTMVDRSDDIVKPKTVSKEVGAAIQKARSAIMIGDKAMTQKELATRCNSTQAIIAQYERGEGVPDQKLLGNLERVLNVKLRGSDIGKPKFEKKEKK
What is the function of this protein?
Transcriptional coactivator that stimulates transcriptional activity by bridging regulatory proteins and TBP, thereby recruiting TBP to promoters occupied by DNA-binding regulators.
What are the official names of this protein?
Multiprotein-bridging factor 1.
What is the protein family that this protein belongs to?
Belongs to the MBF1 family.
Protein: RPOC2_SYNE7
Sequence: MAEAKSAPIFRNRVIDKKQLKKLIGWTFAHYGTAKTAVVADDLKALGFRYATRAGVSISIDDLKVPGSKAELLESAEKRIQETEDRYTRGEITEVERFQKVIDTWANTNDELTDRVVKNFRESDPLNSVYMMAFSGARGNISQVRQLVGMRGLMANPQGEIIDLPIKTNFREGLTVTEYIISSYGARKGLVDTALRTADSGYLTRRLVDVSQDVIIHEVDCGTSRGLFVEAMTDGDRILIPISQRLLGRVTAEAVLDPSTDEVLAEAGQDINEDLANRIEKAGIKKVKVRSPLTCEAARSVCQKCYGWSLAHAQMVDMGEAVGIIAAQSIGEPGTQLTMRTFHTGGVFTGETARLLRAPVAGTIKLGKKARTRPYRTRHGEEALLAEANFDLVLEGKGRKETFAILQGSTIFVQDGDKVAAEAILAEVPVSGRTKRTVEKATKDVATDLAGEIRFQDIVPEEKTDRQGNTTRIAQRGGLLWVLAGDVYNLLPGAEPTVKNGDRVEVGDVLAETKLTTERGGTVRMGEDNGSSTHREVEIITASVVLDTATVKAEASQGREHYVIETKGGQRFNLLAAPGTKVTTGHVVAELIDSRYRTQTGGLLKYSGVEISKKGRAKAKQGYEVTKGGTLLWIPEETHEVNKDISLLNVEDGQLVEAGTEVVKDIFCQTTGIVSVTQNNDILREIVIKPGDVHVLDDPDTAAKYDEGRLVNAGEEVFPGLTAEQLVWAEAVDGTDGPLLLLRPVQELVIPDEPPVPSQDSSQESSSRSIRLRAVQRLQFQDGERIKSVEGVDLLRTQLVLESEEGSSQLSADIELLPDSKDPETLRLQLVIIEPVVIRRDVASDTTHGSTHTELRVKDGQKVKPGAVIACTQIQCKEAGVVRGIQEGSEAVRRLLVERERDCVTLDLDVTAATQLQPGSLIVAGTQLVDGIIAPESGEVRAIAPGQLQLRIARPYRVSQGAVLHVEDKGLVQRGDNLVLLVFERAKTGDIIQGLPRIEELLEARKPKEACILARRPGVAHINYSDDDAIDIQVIEADGTQADYPVGPGQPLIISDGETVDAGQALTDGPANPHDLLEIYYDYFREQLGEDYEAALESLRRVQALLVNEVQSVYQSQGIDISDKHIEVIVRQMTSKVRIDDGGDTIMLPGELHELREVYNSNNTMALTGMAPAQFTPVLLGITKASLNTNSFISAASFQETTRVLTEAAIEGKSDWLRGLKENVIIGRLIPAGTGFKAYEESLLTDVDGGYEDRVYDDDLADVVIDDRAARSYTLNEGRDFSRSMTFAEGESMILDDGEELIDDSSASLRNLVDVDED
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
Protein: MNT1_CANAL
Sequence: MASTRSNARLIRFGIFALVLIGCGYILTRGSSFQPPNYQQTQSPAAHEKQTGNVAAGGGAGSGSAGAQVPLGKNRGPIPKAIMGAGEGGSDAPVPQQDIPDSYTLNDKIKATFVTLARNSDLYSLAESIRHVEDRFNKKFHYDWVFLNDEEFNDEFKETVGSLVSGNTKFGLIPKEHWSYPPWIDQEKAALVREQMREKKIIYGHSESYRHMCRFESGFFWRQEILNDYDYYWRVEPDIKLYCDIDYDIFKWMKDNNKDYAFTISLPEYKETIPTLWDTTKEFIEKNPQYLAQNNLMDWVSDDKGQTYNGCHFWSNFEIGSLAFWRSEAYRKYFEHLDKAGGFFYERWGDAPVHSIAAALFLPREKIHFFEDVGYYHVPFTNCPVDKEVRKARNCNCDPNKDFTWRGYSCTTKYYTLNNFKRQKGWEKYTA
What is the function of this protein?
Involved in O-glycosylation of cell wall and secreted proteins.  Transfers an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->2)-D-mannosyl-D-mannose linkage.  Mainly responsible for the addition of the second mannose residue in an O-linked mannose pentamer.  Can also substitute for MNT2 by adding the third mannose residue.  Important for adherence to host surfaces and for virulence.
What are the official names of this protein?
Glycolipid 2-alpha-mannosyltransferase 1, Alpha-1,2-mannosyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 15 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: QUEE_ARCFU
Sequence: MRANLIEIFESIQGEGFYIGVRQLFVRFAGCNLNCYYCDTPKTSENCLDLTANRTLKNPVSAEYVQGRIDSSKVHSVCFTGGEPMLQAEFIASLSKTHPFYLESNMTLPEKAKKLKFCDYVAGDLKVREAGLKNYDEVFQKTVKCFKVLRNTRRRKTFCKIVLPDKFDADEVLNSAYEIKNYVFGFVLQPVFGSRVEKILKLQKRMIDFADTRVIPQVHKYLGVR
What is the function of this protein?
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
What are the official names of this protein?
7-carboxy-7-deazaguanine synthase, CDG synthase, Archaeosine biosynthesis protein QueE.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Protein: ATPH_GUITH
Sequence: MNPIVSAASVVASGLSVGLAAIGPGIGQGTAAAQAVEGIARQPEAEGRIRGTLLLSLAFMESLTIYGLVVALALLFANPFTS
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, chloroplastic, ATP synthase F(0) sector subunit c, ATPase subunit III, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: MAO1_YERPB
Sequence: MELEYESKRPLYIPYAGPILLEFPLLNKGSAFTNDERNHFNLHGLLPEAVETIEEQAERAYRQYQDFKNDDDKHIYLRNIQDTNETLFYRLLEAHLSEMMPIIYTPTVGEACEHFSDIYRRARGLFISYPNREHIDDMLQNATKQNVKVIVVTDGERILGLGDQGIGGMGIPIGKLSLYTACGGISPAYTLPVVLDVGTNNPQRLNDPLYMGWRHPRISGDEYYAFVDEFIQAVKRRWPNVLLQFEDFAQKNATPLLNRYRDELCCFNDDIQGTAAVTLGSLIAASHAAGSQLRDQTVTFLGAGSAGCGIAEQIIAQMMSEGLSEIQARARIFMVDRFGLLTDKLPNLLDFQSKLVQKSDDLHHWNLHNDAISLLDVVRNAKPTVLIGVSGQPGLFTEELIREMHSHCARPIVMPLSNPTSRVEARPEDIINWTDGAALVATGSPFPPVSYKEKLYPIAQCNNSYIFPGIGLGVLASGASRVTDGMLMAASRALAESSPLARHGEGALLPNIDDIQAVSKAIAMRVGQAAQLQGVAIVTSEEALSKAIEHNYWQPQYRSYKRTSF
What are the official names of this protein?
NAD-dependent malic enzyme, NAD-ME.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
Protein: RBL_ADOMO
Sequence: SAGFKAGVKDYKLTYYTPDYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTNLDRYKGRCYHIEPVAGEETQFIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPVAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEALYKAQAETGEIKGHYLNATAGTCEEMMKRAIFARELGVPIVMHDYLTGGFTANTTLAHYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRMSGGDHIHSGTVVGKLEGEREITLGFVDLLRDDFIEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRXXAREGNEIIREASKWSPELAAACEVWKEIKFEFEAMDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RHES_RAT
Sequence: MMKTLSSGNCTLNVPAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIHGDMYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDSRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICGNKNDHSELCRQVPAMEAELLVSGDENCAYFEVSAKKNTNVNEMFYVLFSMAKLPHEMSPALHHKISVQYGDAFHPRPFCMRRTKVAGAYGMVSPFARRPSVNSDLKYIKAKVLREGQARERDKCSIQ
What is the function of this protein?
GTPase signaling protein that binds to and hydrolyzes GTP.  Regulates signaling pathways involving G-proteins-coupled receptor and heterotrimeric proteins such as GNB1, GNB2 and GNB3.  May be involved in selected striatal competencies, mainly locomotor activity and motor coordination.
What are the official names of this protein?
GTP-binding protein Rhes, Ras homolog enriched in striatum, SE6C.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. RasD family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Note=Found in granular structures throughout the cytosol.
Protein: PLSY_PSEE4
Sequence: MFWSLALLAYLLGSLSFAIVLSRLTGSPDPRSSGSGNAGATNMLRLAGRKLAILTLLGDLCKGMLPVLLARQVGLDPQEQAWVGICAVLGHLFPVYFRFQGGKGVATAAGMLMALYFPAALLAIGAWVLTFYLTRTSSLAALIATPLTLPLLAWREPEALLPMTVLTLMIVWRHRSNLRDLFAGRERHF
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.