PharMolix/UniProtQA huggingface dataset:
Protein: KPPR_CHLRE
Sequence: MAFTMRAPAPRATAQSRVTANRARRSLVVRADKDKTVVIGLAADSGCGKSTFMRRMTSIFGGVPKPPAGGNPDSNTLISDMTTVICLDDYHCLDRNGRKVKGVTALAPEAQNFDLMYNQVKALKEGKSVDKPIYNHVSGLIDAPEKIESPPILVIEGLHPFYDKRVAELLDFKIYLDISDDIKFAWKIQRDMAERGHSLESIKSSIAARKPDFDAYIDPQKKDADMIIQVLPTQLVPDDKGQYLRVRLIMKEGSKMFDPVYLFDEGSTISWIPCGRKLTCSFPGIKMFYGPDTWYGQEVSVLEMDGQFDKLEELIYVESHLSNTSAKFYGEITQQMLKNSGFPGSNNGTGLFQTIVGLKVREVYERIVKKDVVPV
What are the official names of this protein?
Phosphoribulokinase, chloroplastic, PRK, PRKase, Phosphopentokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoribulokinase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RECO_LIGS1
Sequence: MIYKNVEFSAIVTKRKNYRERDMLVTMFTDKYGFKTFFVRGVRKRGFKLGAAILPFTHGTYIGSINSEGLSFITATKGIDQFQSINQDIILNAYATYILELVKAAFEDSIDVTNTLWFEKVLKALSLINDGFDAQIIANIIEVQLLGKFGVQPNWRSCVICGETQSQFDYSESYGGILCRKHWYMDKNRLNLDQRTMYYLRKFSIVDLNYLNSIKVNADTKKKLKLTLNEIYDNQVGIYVKARSFIDKMTKVENNLLKKD
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: PLSX_MYCPU
Sequence: MKTIAFDVMGNDFGPQAAVQASLEFVQKNPDFQIILVGDKKEIEKFTKETSQIKILESPNIASSKDGLRQVSKMENSMNSALDLVVEKKADAVLSSGDSGAYLTSALLKVKRLKGILRPAFMPIFPTIVKDKKILVLDVGANLETKVEYLIQWTKLASIFSNKILKVKNPKCALVNIGVEDYKGFDFHKQANEELKQSNANYIGFLEPRNILDGKVDVAVVDGYGGNLILKSMEGAVLALKKVIKESITKTFFRKILALFLKKAFKDAAERLDYRNVGAAWVLGLNGIVVKSHGSNDFKAYLGALEQVKQGINAKVIDVFRETLE
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: ACP_BACMK
Sequence: MADVLERVTKIVVDRLGVEETEVVPAASFKEDLGADSLDVVELVMQLEDEFEMEISDEDAEKIATVGDAVTYIESHL
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SH21A_BOVIN
Sequence: MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYQGYIYTYRVSQTETGSWSAETAPGVHKRFFRKIKNLISAFQKPDQGIVIPLQYPVEKKPSARSTQGATGRRDDPDVFLKTP
What is the function of this protein?
Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7.  In SLAM signaling seems to cooperate with SH2D1B/EAT-2.  Initially it has been proposed that association with SLAMF1 prevents SLAMF1 binding to inhibitory effectors including INPP5D/SHIP1 and PTPN11/SHP-2.  However, by simultaneous interactions, recruits FYN which subsequently phosphorylates and activates SLAMF1.  Positively regulates CD244/2B4- and CD84-mediated natural killer (NK) cell functions.  Can also promote CD48-, SLAMF6 -, LY9-, and SLAMF7-mediated NK cell activation.  In the context of NK cell-mediated cytotoxicity enhances conjugate formation with target cells (By similarity).  May also regulate the activity of the neurotrophin receptors NTRK1, NTRK2 and NTRK3 (By similarity).
What are the official names of this protein?
SH2 domain-containing protein 1A.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_MOUSE
Sequence: METVVRRCPFLSRVPQAFLQKAGKSLLFYAQNCPKMMEVGAKPAPRTLSTSAVHCQQVKETPPANEKEKTAKAAVQQAPDESQMAQTPDGTQLPSGHPSPATSQGSGSKCPFLAAQLSQTGSSVFRKASLELQEDVQEMHAVRKEAAQSPVPPSLVNVKTDGEDPSRLLKNFQDIMRKQRPERVSHLLQDNLPKSVSTFQYDHFFEKKIDEKKNDHTYRVFKTVNRRAQIFPMADDYTDSLITKKQVSVWCSNDYLGMSRHPRVCGAVMETVKQHGAGAGGTRNISGTSKFHVELEQALADLHGKDAALLFSSCFVANDSTLFTLAKMMPGCEIYSDSGNHASMIQGIRNSRVPKYIFRHNDVNHLRELLQRSDPSVPKIVAFETVHSMDGAVCPLEELCDVAHEFGAITFVDEVHAVGLYGARGGGIGDRDGVMPKMDIISGTLGKAFGCVGGYIASTSLLIDTVRSYAAGFIFTTSLPPMLLAGALESVRILKSSEGRALRRQHQRNVKLLRQMLMDAGLPVIHCPSHIIPVRVADAAKNTEICDELMTRHNIYVQAINYPTVPRGEELLRIAPTPHHTPQMMNFFVEKLLVTWKRVGLELKPHSSAECNFCRRPLHFEVMSEREKAYFSGMSKMVSAQA
What is the function of this protein?
Catalyzes the pyridoxal 5'-phosphate (PLP)-dependent condensation of succinyl-CoA and glycine to form aminolevulinic acid (ALA), with CoA and CO2 as by-products.
What are the official names of this protein?
5-aminolevulinate synthase, non-specific, mitochondrial, ALAS-H, 5-aminolevulinic acid synthase 1, Delta-ALA synthase 1, Delta-aminolevulinate synthase 1.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein. Note=Localizes to the matrix side of the mitochondrion inner membrane.
Protein: PYRD_COXBN
Sequence: MIYRYLRPWLFKLEPETAHALTLNCLKWFYCYWLINRRLQRFPQKPTVVFGIEFPNPVGLAAGLDKNGEYMDELLGLGFGFIEVGAVTPKPQPGNSKPRIFRLPQARALINRMGFNNLGVDYLVEQLKRRKVKGIVGVNIGKNLTTPLEKAHEDYQNCFEKLYSYVDYVTINISSPNTPELRQLQSERYLADLLTRLKEDQRRLEDQYHKRVPLFLKIAPDLTPEEIQTIATLALQHRIEGIVATNTSCSRQGTEKLPNANEAGGLSGKPLFPMTLQVVKQLHSFLGDEIPIVAVGGIFSGENAQTLINAGARLVQLYTGLIYEGPELVKNIVEFLTLSRQTREGIN
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL35_CALS8
Sequence: MPKLKTHRGLAKRIKISGSGKYLRKKAGKSHLLSGKSRKRKRNLKKTVIVDSTNVKAVKKLLPYL
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: RL19_PORG3
Sequence: MDFIKIVNEEFKSGKEHPKFNSGDTITVEYRIKEGNKERIQKYRGVVIRISGHGDKKRFTVRKISDGIGVERIFPIESPFIENITVEKYGKVRRAKLYYLRGLTGKKARIKERRVALSSKD
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: YOR22_YEAST
Sequence: MLRFTHRGLPSSTRFRNIFVRLNHIYVPWFYAIDVPNSKPYLPTYQTLHSPKKFKPFSVDDSNRLEKASKRQERRPVLVNEDYLFKVDLSHMELSPTYWEGPTYQVRRGVWFDSSNQPLSSDLTSEIEGLYKQLKFDDSNDDPTTTPPAESQDIFRLKGKYPVDKENEGEQKNGSSNKDENESTFKFILFANKQTAFLLSDLDGGKLQLAFLRSNLAQSLPINATMITRSYKYSSSATTKQTSTSFKAAKTPQTEVADGSNSSKSRSIETKLEKKVSNLFNLSDFLQLFNGNASKDQDDAQSLEKQMETDYNNADNSQGANASSKIEDGKNSGASDRQIRSNRRDVDNLILCVHGIGQTLGKKYEYVNFAHTVNLLRSNMKKIYNNSEKLQSLNTAPDYKSNCNVQVLPITWRHSISFQTDAKEENIENPDLPTLSQVTVNGVLPLRKLLADGLLDILLYVEPYYQDMILQQVTSQLNKTYRIFKEFNPEFDGKVHLVGHSLGSMILFDILSKQKKYELEFQVDNLFFIGSPIGLLKLIQRTKIGDRPEFPNDLERKLTVQRPQCKDIYNVYHVCDPISYRMEPLVSKEMAHYEQTYLPHCSEAYGLTSKVLEFGENIWKDLPGTDENNLQSKKTSPEKKEVKLSENLTRMLTGLNYTGRLDYAMSPSLLEVDFISAIKSHVSYFEEPDIAAFILKEILSKHENASEIYVKRKTG
What is the function of this protein?
Probable phospholipase that hydrolyzes phosphatidic acid.
What are the official names of this protein?
Probable phospholipase YOR022C, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PA-PLA1 family.
Protein: CYAA_SALTY
Sequence: MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPSGICFYTPDETQRHYLNELELYRGMTPQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCHQSWLDGEERQLLQRKCSLLESWAASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHILLLDEFYRTAVRLAGKRILWSMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLDPYCMMLERVTEYLTAIEDPTRLDLVRRCFYLKVCEKLSRERACVGWRREVLSQLVSEWGWDDARLTMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIHVPPGRANRSGWYLYNRAPNMDSIISHQPLEYNRYLNKLVAWAWFNGLLTSRTHLFIKGNGIVDLPKLQEMVADVSHHFPLRLPAPTPKALYSPCEIRHLAIIVNLEYDPTAAFRNKVVHFDFRKLDVFSFGEEQNCLIGSIDLLYRNSWNEVRTLHFNGEQAMIEALKTILGKMHQDAAPPDSVEVFCYSQHLRGLIRTRVQQLVSECIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGAISHNKLHGLSVQVETNQVKLPSVVDGFASEGIIQFFFEETGDEKGFNIYILDESNRAEVYHHCEGSKEELVRDVSRFYSSSHDRFTYGSSFINFNLPQFYQIVKTDGRAQVIPFRTQPINTVPPANQDHDAPLLQQYFS
What are the official names of this protein?
Adenylate cyclase, ATP pyrophosphate-lyase, Adenylyl cyclase.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_PECAS
Sequence: MSNQLSPKPPVNPIVMGKIGSAYGIRGWLRVFSSTEDADSIFDYQPWFIQSKSGWQLVEIEGWKYHNQDLIIKVKGADDRDAANLLTNCEIVVDSSQLPDLGVGDYYWKDLIGCQVVTVTGYELGKIIDMMETGSNDVMVIKANLKDAFGVKERLVPFLTEQVVKRVDLSAQTIEVDWDPGF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GARL_ECO55
Sequence: MNNDVFPNKFKAALAAKQVQIGCWSALSNPISTEVLGLAGFDWLVLDGEHAPNDISTFIPQLMALKGSASAPVVRVPTNEPVIIKRLLDIGFYNFLIPFVETKEEAEQAVASTRYPPEGIRGVSVSHRANMFGTVADYFAQSNKNITILVQIESQQGVDNVDAIAATEGVDGIFVGPSDLAAALGHLGNASHPDVQKAIQHIFNRASAHGKPSGILAPVEADARRYLEWGATFVAVGSDLGVFRSATQKLADTFKK
What is the function of this protein?
Catalyzes the reversible retro-aldol cleavage of both 5-keto-4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde.
What are the official names of this protein?
5-keto-4-deoxy-D-glucarate aldolase, KDGluc aldolase, KDGlucA, 2-dehydro-3-deoxy-D-glucarate aldolase, 2-keto-3-deoxy-D-glucarate aldolase, 5-dehydro-4-deoxy-D-glucarate aldolase, Alpha-keto-beta-deoxy-D-glucarate aldolase.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily.
Protein: RL10E_META3
Sequence: MALRPSKCYREINKPAYTRKKYIRAVPQPKVVHYVNGNKGGDFPVEVHLVVKDDIQIRHNALESARIVGNKYTQNKCGRLGYKFQIRVYPHQVLRENKMASGAGADRISDGMRLSFGKAVGTAARVRKGQKIITISTTPENVIHAKEALRRCNMKMPVKCKIVIGKGAELVKN
What are the official names of this protein?
50S ribosomal protein L10e.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: DPH5_MOUSE
Sequence: MLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLILADREEVEQEADNIFKDADVSDVAFLVVGDPFGATTHSDLILRATKLGIPYQVIHNASIMNAVGCCGLQLYRFGETVSIVFWTDTWRPESFFDKVKRNRANGMHTLCLLDIKVKEQSLENLIRGRKIYEPPRYMSVNQAAQQLLEIVQNHRARGEEPAITEETLCVGLARVGAEDQKIAAGTLQQMCTVSLGEPLHSLVITGGNLHPLEMEMLSLFSIPESQSTDGL
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester.  The four successive methylation reactions represent the second step of diphthamide biosynthesis.
What are the official names of this protein?
Diphthine methyl ester synthase, Diphthamide biosynthesis methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the diphthine synthase family.
Protein: RNR_SHIFL
Sequence: MSQDPFQEREAEKYANPIPSREFILEHLTKREKPASRDELAVELHIEGEEQLEGLRRRLRAMERDGQLVFTRRQCYALPERLDLVKGTVIGHRDGYGFLRVEGRKDDLYLSSEQMKTCIHGDQVLAQPLGADRKGRREARIVRVLVPKTSQIVGRYFTEAGVGFVVPDDSRLSFDILIPPDQIMGARMGFVVVVELTQRPTRRTKAVGKIVEVLGDNMGTGMAVDIALRTHEIPYIWPQAVEQQVAGLKEEVPEEAKAGRVDLRDLPLVTIDGEDARDFDDAVYCEKKRGGGWRLWVAIADVSYYVRPPTPLDREARNRGTSVYFPSQVIPMLPEVLSNGLCSLNPQVDRLCMVCEMTVSSKGRLTGYKFYEAVMSSHARLTYTKVWHILQGDQDLREQYAPLVKHLEELHNLYKVLDKAREERGGISFESEEAKFIFNAERRIERIEQTQRNDAHKLIEECMILANISAARFVEKAKEPALFRIHDKPSTEAITSFRSVLAELGLELPGGNKPEPRDYAELLESVADRPDAEMLQTMLLRSMKQAIYDPENRGHFGLALQSYAHFTSPIRRYPDLTLHRAIKYLLAKEQGHQGNTTETGGYHYSMEEMLQLGQHCSMAERRADEATRDVADWLKCDFMLDQVGNVFKGVISSVTGFGFFVRLDDLFIDGLVHVSSLDNDYYRFDQVGQRLMGESSGQTYRLGDRVEVRVEAVNMDERKIDFSLISSERAPRNVGKTAREKAKKGDAGKKGGKRCQVGKKVNFEPDSAFRGEKKTKPKAAKKDARKAKKPSAKTQKIAAATKAKRAAKKKVAE
What is the function of this protein?
3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity).  Required for the expression of virulence genes on the large plasmid of S. flexneri at the post-transcriptional level.
What are the official names of this protein?
Ribonuclease R, RNase R, Protein VacB.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family. RNase R subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FASD_ECOLX
Sequence: MNKYPPLLTMLIIGIGSNAVAGDYFDPSLLATDIGNNDKLDLSLFSHPGGGVKGEREVSVYINDFFYKNVTLDFENGISGALEPIFPSGFFDNILASPYRSIKEKELISTADFLSLVPYGMVRFDQAIARVDISIPQAYLGRDAQMKSAPESWNQGVPALLIDYRLSGSKNKYNYGSSQNFYANAFLGFNLMGWRLRTTTNYMSYNSKDLYNKGERQGSFNFYNTYLEKDIGYLRSTLRLGELSTRGMILESFNFKGGKIYSNDEMLNDRLRSYTPTVRGIASSQAVVTIKQGGVVILQKNVPPGPFEINDFSLSGYSGDLYVNIKEADGSEHSFIQPFSTLPEMKREGVSGYEISLGHYNNSGATQYYNESPFLYASWSRGYRNGMTLYSETIQSRKYQLLGVGSTLSLGDFGAVSGDASLSRANKYDKIHSGQSYGLKYSKNKVDTGTTVTLATYRYSTKDFYSFNDFVSKNDSVQYVWDNRLKNRITLSLNQSLDDYGSLSLIASQQNYWTSDYVSRSFSLSHSFGWNDIFFSTSFSLDQKEGDNALRNNNKVFGFYSSIPLSKLIGKNESTYSTLSYNVTKINNQVRNTATLAGKVPGSMAQYRFSSGWANTEQSSNKALSVNWDGDLLDGSLGYTSSGKNRITDYSLSGSAILYPWRLAIGSDSVINGAAVVETEFISGIKVRQGGETSLLGTAIVTSMQPYTENRIDLDTQNIPDDLFISNASKKIVPEKGAVVPVKYNLFKGKQIVFSLKRYDGTPLPFGSVVSLVGSDSEITGIIDDAGRVYLAGIPSKGILHGAWGYNKSCEVSFNLNGKPSNNSNEIIEYEGVCK
What is the function of this protein?
Involved in the export and assembly of the 987P fimbriae subunits across the outer membrane.
What are the official names of this protein?
Outer membrane usher protein FasD.
What is the protein family that this protein belongs to?
Belongs to the fimbrial export usher family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: EFGM_CAEBR
Sequence: MSPLGRFSAVAQSRRQLNNVFRRFTSNEAPSVIVPGVRPIERIRNIGISAHIDSGKTTVTERILYYAGRIDSMHEVRGKDDVGATMDFMELERQRGITIQSAATYVDWHGTNINIIDTPGHVDFTVEVERALRVLDGAVLVLCGVGGVQSQTFTVNRQLARYNVPFICFVNKMDRNGASPLKALDGLRNKLNHNAALVHLPIGKDSNFNGIVDLVEGHALYYEGEGGLIVRKDEIPKDLRVEAEDRRQELIEHIANVDETLGEMFLNDQKPDVKQIHEAIRRTVVKRQFVPVLSGSALKNKGVQTMIDSVVKYLPDPSEVVNRATVKTETGEEKRIILSPERNNDKPFVGLAFKLEAGKYGQLTYFRVYQGQLSKGDTVYASRDGRKVRVQRLVRMHAADMEEITTAYAGDICATFGLDCHSGETFSTDQNLAPHCESMHIPEPVISMAIKPVNRKDADNFIKALTRFTKEDPTFRREYNQEAKETIVSGMGELHLEIYAQRMKSEYNCPVELGKPSVAYRECLGAPYKFHFRHKKQTGGQGQFGEIEGVIDPLPADRNTVVEFSDETFGNNIPKNLFPALKKGLDAIVAEGPLIKSRIAGIHVRIQDGATHAVDSTEIAMINTMQNMMRESFEKASWLLLEPIMKVEVTTPAEFQGNVVTSALSDMFGYTSELRSLTEGKGEFSMEYSRYAPTSLEAQDRVQAEWRQLHGIADPNEKGKKKKK
What is the function of this protein?
Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, mitochondrial, EF-Gmt, Elongation factor G 1, mitochondrial, mEF-G 1, Elongation factor G1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NIRA_EMENI
Sequence: MGEKLDPELSSDGPHTKSSSKGQGTSTDNAPASKRRCVSTACIACRRRKSKCDGNLPSCAACSSVYHTTCVYDPNSDHRRKGVYKKDTDTLRTKNSTLLTLIQALLNYEEEDAFDLVRQIRSCDNLEDVAQSLVNQEKKSSGWLSNAVIHEENDIAQTDQFESELAGKMSNLVLDGSRKFIGGTSNLIFLPPGSELNEFKPGLATNGDLEGSVTRWTTVTDDQQLISHLLTMYFSWHYPFFTTLSKELFYRDYSRGVPSQYCSSLLVNTMLALGCHFSSWPGAREDPDNSATAGDHFFKEAKRLILDNDELVNSKLCTVQALALMSVREAGCGREGKGWVYSGMSFRMAFDLGLNLESSSLRDLSEEEIDARRITFWGCFLFDKCWSNYLGRQPQFTTANTSVSAVDILPNEESTLWSPYSDMGPSREYAQPSRTRAVADQISQLCKISGDLVVFFYDLAPKEKPSSKQLELKKLSEIHTRLEAWKKGLPKELEPREGQLPQALLMHMFYQLLLIHLYRPFLKYTKSTSPLPQHVSPRKLCTQAAAAISKLLRLYKRTYGFKQICNIAVYIAHTALTIHLLNLPEKNAQRDVIHGLRHLEEMGESWLCARRTLRILDISASKWQVQLPREAVIVFEQTHARWGSWGPWDQAASPSTTSDSPPSVSSQSVVATTDLSQPVSQSAGNQPANPSMGTSPNLTQPVASQYSSTPSGPVSVSAMRAVQRSFSAQLAHNEARQPEPTYLRPVSTSYGPVPSTQSAQEQWYSPTEAQFRAFTAAHSMPTTSAQSPLTTFDTPENLVEESQDWWSRDVNALQLGAEDWTQNWNNGLPTTSADWRYVDNVPNIPSTSAPDADYKPPQPPPNMARPNQYPTDPVANVNSNQTNMIFPGSFQR
What is the function of this protein?
Pathway-specific regulatory gene of nitrate assimilation; it activates the transcription of the genes for nitrate and nitrite reductases (niaD and niiA).
What are the official names of this protein?
Nitrogen assimilation transcription factor nirA.
What are the subcellular locations of this protein?
Nucleus.
Protein: AROA_PSESM
Sequence: MRPQATLTVMPVERPLVGRVSPPGSKSITNRALLLAGLAKGTSRLTGALKSDDTRVMSEALRLMGVQVDEPDDSTFVVTSSGHWQAPQQALFLGNAGTATRFLTAALANFEGDFVVDGDEYMRKRPIGPLVDALQRMGVEISAPSGCPPVAIKGKGGLQAGRIEIDGNLSSQYVSALLMAGACGKGSLEVALTGSEIGARGYVDLTLAAMQAFGAEVQAIGDAAWKVSATGYHATDFHIEPDASAATYLWAAQALTEGNIDLGVASDAFTQPDALASQIIDSFPNMPAVIDGSQMQDAIPTLAVLAAFNRQPVRFVGIANLRVKECDRISALCDGLCAIAPGLAVEEGDDLIVHANPALAGTTVNALIDTHSDHRIAMCFALAGLKIKGIHIQDPDCVAKTYPGYWDALASLGVSVQR
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TELL_STAAS
Sequence: MTENKSFKESHPLDDFISDKELSNTTIQKEKLTIEQQKQVDTISKQINPLDNEGLLAFGSDLQKQMSQFSHQMLDEVQSKDVGPIGDTLSDLISKLKSVNPNELNTDKPSMLKRIFSRAKSSINEIFSRMQSVSAQVDRITIQLQKHQTHLTRDIELLDTLYDKNKQYFDDLSLHIIAAQQKKLQLENEKLPQLQQQAQQSTNQMDIQHVADMQQFIDRLDKRIYDLQLSRQIALQTAPQIRMIQNVNQALAEKIQSSILTSIPLWKNQMAIALTLMRQRNAVAAQRAVTDTTNDLLTANAEMLKQNAIETATENERGIVDLDTLKRTQRNIIETIEETLIIQQHGREERQLAEKELQQLEQDLKSHLVNIKGTNKQS
What are the official names of this protein?
TelA-like protein SAS1347.
What is the protein family that this protein belongs to?
Belongs to the TelA family.
Protein: CHEB2_METAC
Sequence: MTIRALVVDDSALIRKVLSDILNEDPKIRVVGTAVNGKDGLEKVIKLRPDVVLLDNVMPVLDGLKTLARIMKEQPTPVVIVSALGERAEEITLTAFEYGAVDVIEKPSGILSQSMPEMAEEICRKVRTAPKANLKNLECMRDSEPLNPEKRETKENRVLKKAAPRNILAIGASTGGPRALEKLICSLPAELPAAVLVVQHMPPGFTASLSKRLDSKSALRVKEAQEGDRVEDGTVLIAPGNYHMEIVRNKVNSLEEETIHLSCGPKELGSRPSVNVLFRSIASVYGSRVISLVLTGMNCDGADGAEEIKKMGGKVIAEARSSCVVYGMPGEIVRRNLADLVLPLDKMAEEIIRIIG
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 2.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRAAH_PSEPW
Sequence: MQHYVTPDLCDAYPDLVQVLEPMFSNFGGRDSFGGQIVTIKCFEDNSRVKEQVELDGKGKVLVVDGGGSLRCALLGDMLAEKAAKNGWEGLVIYGCVRDVDVLIQTSVGVQALASHPMKTDKRGIGDLNVAVTFAGVTFRPGEYVYADNNGVIVSPSPLEMPQ
What is the function of this protein?
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.  Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
What are the official names of this protein?
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase, HMG aldolase, Oxaloacetate decarboxylase, OAA decarboxylase, Regulator of ribonuclease activity homolog, RraA-like protein.
What is the protein family that this protein belongs to?
Belongs to the class II aldolase/RraA-like family.
Protein: VATI_ARCFU
Sequence: MLKPERMVRVSVVGPREKLGETADLLHRLNLVHIEEPEESEYFRIGEPHPDASVVSRALVQMRSFISHLKLDPSRIVPRRKFRESEIEAQLKEKLDEYQQLIGERIEYLRSVDEKIASLQEQLNQIEPLKRLGIPARLLKGYKTLRVFVGFVKENPTEKFAQVTSDFEVFATEYEKELVVAVFVKAEYGDEFLRILQECGYREIQVPDVEDFEAKISEIEKEIESLKSRKEQVEKEIEEVKVKEAETLLAIEEYLSSQMDKYELPLRTLVSKYSFVLVGYLPAKALNEFKAKMDANGVAVEVLDEEGEPPTKLSNPAGVRNFELLTTTFGIPKYKEIDPTVFIAIFFPIFFGMMLGDIGYGLLVTVISLYLKRVFKTEGWQRMLNIGVYAGVMSIIFGFIYGECFGPFIVPGEYEPYQIHFIGSQLEHLYEFHHGHPIFDRVEEMGVKILLFATIVIGIAKILFGFALGFYNVYVEHGLKDAILEKLSWIIGVLGLAMIIFGFAYNVGVFYQLGMGPNPGDVPPLPLPGLMEGWQAGLNVYYLAALPLLVVWFILFVMGEVPKMGAMGVILAVELLTWFGQIMSYARLLAIGLSSVYIAFVINFIGMKLIDPVGISIPIVGAIVLLIGHVGNLILGILDPGLQSLRLHYVEFFTKFFEGGGRLYEPFGRIKRFIEE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit I, V-ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase 116 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GDF6_HUMAN
Sequence: MDTPRVLLSAVFLISFLWDLPGFQQASISSSSSSAELGSTKGMRSRKEGKMQRAPRDSDAGREGQEPQPRPQDEPRAQQPRAQEPPGRGPRVVPHEYMLSIYRTYSIAEKLGINASFFQSSKSANTITSFVDRGLDDLSHTPLRRQKYLFDVSMLSDKEELVGAELRLFRQAPSAPWGPPAGPLHVQLFPCLSPLLLDARTLDPQGAPPAGWEVFDVWQGLRHQPWKQLCLELRAAWGELDAGEAEARARGPQQPPPPDLRSLGFGRRVRPPQERALLVVFTRSQRKNLFAEMREQLGSAEAAGPGAGAEGSWPPPSGAPDARPWLPSPGRRRRRTAFASRHGKRHGKKSRLRCSKKPLHVNFKELGWDDWIIAPLEYEAYHCEGVCDFPLRSHLEPTNHAIIQTLMNSMDPGSTPPSCCVPTKLTPISILYIDAGNNVVYKQYEDMVVESCGCR
What is the function of this protein?
Growth factor that controls proliferation and cellular differentiation in the retina and bone formation.  Plays a key role in regulating apoptosis during retinal development.  Establishes dorsal-ventral positional information in the retina and controls the formation of the retinotectal map (PubMed:23307924).  Required for normal formation of bones and joints in the limbs, skull, digits and axial skeleton.  Plays a key role in establishing boundaries between skeletal elements during development.  Regulation of GDF6 expression seems to be a mechanism for evolving species-specific changes in skeletal structures.  Seems to positively regulate differentiation of chondrogenic tissue through the growth factor receptors subunits BMPR1A, BMPR1B, BMPR2 and ACVR2A, leading to the activation of SMAD1-SMAD5-SMAD8 complex.  The regulation of chondrogenic differentiation is inhibited by NOG (PubMed:26643732).  Also involved in the induction of adipogenesis from mesenchymal stem cells.  This mechanism acts through the growth factor receptors subunits BMPR1A, BMPR2 and ACVR2A and the activation of SMAD1-SMAD5-SMAD8 complex and MAPK14/p38 (By similarity).
What are the official names of this protein?
Growth/differentiation factor 6, GDF-6, Bone morphogenetic protein 13, BMP-13, Growth/differentiation factor 16.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.