PharMolix/UniProtQA huggingface dataset:
Protein: RL20_ANAMF
Sequence: MARVKRGVTARARHKKVVALAKGYRGRSKNCYRAALQRLEKALVYAYRDRRNRKRDFRRLWIVRINAAARQWGIKYSQLMKGMALCGIELNRKMLAEMAVNDKAAFEKVVSAVAGTCGYACAVNQQDK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: RLA1_YEAST
Sequence: MSTESALSYAALILADSEIEISSEKLLTLTNAANVPVENIWADIFAKALDGQNLKDLLVNFSAGAAAPAGVAGGVAGGEAGEAEAEKEEEEAKEESDDDMGFGLFD
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S acidic ribosomal protein P1-alpha, A1, L12eIIA, Large ribosomal subunit protein P1-A, P1A, YP1alpha.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein P1/P2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C71A1_ZINZE
Sequence: MEAISLFSPFFFITLFLGFFITLLIKRSSRSSVHKQQVLLASLPPSPPRLPLIGNIHQLVGGNPHRILLQLARTHGPLICLRLGQVDQVVASSVEAVEEIIKRHDLKFADRPRDLTFSRIFFYDGNAVVMTPYGGEWKQMRKIYAMELLNSRRVKSFAAIREDVARKLTGEIAHKAFAQTPVINLSEMVMSMINAIVIRVAFGDKCKQQAYFLHLVKEAMSYVSSFSVADMYPSLKFLDTLTGLKSKLEGVHGKLDKVFDEIIAQRQAALAAEQAEEDLIIDVLLKLKDEGNQEFPITYTSVKAIVMEIFLAGTETSSSVIDWVMSELIKNPKAMEKVQKEMREAMQGKTKLEESDIPKFSYLNLVIKETLRLHPPGPLLFPRECRETCEVMGYRVPAGARLLINAFALSRDEKYWGSDAESFKPERFEGISVDFKGSNFEFMPFGAGRRICPGMTFGISSVEVALAHLLFHFDWQLPQGMKIEDLDMMEVSGMSATRRSPLLVLAKLIIPLP
What is the function of this protein?
Catalyzes the conversion of alpha-humulene to 10-hydroxy-alpha-humulene in the second step of zerumbone biosynthesis, a predominating potential multi-anticancer agent.
What are the official names of this protein?
Alpha-humulene 10-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: EFP_BACC4
Sequence: MISVNDFRTGLTISVDNALWQVLDFQHVKPGKGAAFVRSKLRNLRTGSVQEKTFRAGEKVEKAHIENRRMQYLYASGEAHVFMDNGTYEQIELGEKQIERELKFLKENMEVAIMTYQGEVLGVELPNTVELQVTETEPGIKGDTASNVTKPATLETGLVVQVPIFINEGEMLIINTGEGKYVSRA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATB22_ARATH
Sequence: MEYWSSSFIDGASSSSFISPFYNFDHFSGNQDNRCLGTMMGAQQDILHVPLAMVESGYGEESNSFNGQEKKKKKMTSEQLKFLERSFQEEIKLNPDRKMKLNPDRKMKLSKELGLQPRQIAVWFQNRKARWKNKQLEHLYESLRQEFDIVSREKELLQEELIQLKSMIREDSSCKKKQTWEKACS
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
Homeobox-leucine zipper protein ATHB-22, HD-ZIP protein ATHB-22, Homeodomain transcription factor ATHB-22.
What is the protein family that this protein belongs to?
Belongs to the HD-ZIP homeobox family. Class I subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARP1_METGA
Sequence: MSQSLTSSVETDSKTGSSKAISFQDYLDLSALDWARLRAILAPTLYVDYTKIGKEKWDAMSADDFMAMVSNDDFLGDPCVKTQHLIGATYWERVSESKVIGHHQLRAAHQVYTSPDLKTVKLRGHSHATNEHYYVKSSGVWKFAGLKPEVRWNEYKFEEVFKGSYTQSEKQS
What is the function of this protein?
Scytalone dehydratase-like protein; part of the Pks2 gene cluster that mediates the formation of infectious structures (appressoria), enabling these fungi to kill insects faster (PubMed:29958281).  The product of the Pks2 gene cluster is different from the one of Pks1 and has still not been identified (PubMed:29958281).
What are the official names of this protein?
Scytalone dehydratase-like protein Arp1.
What is the protein family that this protein belongs to?
Belongs to the scytalone dehydratase family.
Protein: PTCD3_XENLA
Sequence: MAAPCVRLGSVRCTGTLLRYFCGSARHQAAAASHEEIDIPRRKSWDKTAVLQALAYTVSHDPTAAHYMFQDDPFLVPKTSSEFRLYSLSKESGRNAAKYIIGTHPKLFQNDIAEPHIPCLMPENFQPQIEGVSEEALKERIQLRRIKESIDLFDQLLQGGTAPSLETTNRLLDLICFYGDREPTRDIQTSEQNQQDDQDQQETEDSKKRPGQYRKASEILGSWRENNNAERIFNLMPERNAHSFCTLIQGMVKYGSSNKAFNTYTDLMNNRLTADVQTFNALILAAPDMKEKYNEKWDLIVELLKHMVQQNVRPNLLTFNSVLKSLRKCGTMARGLALQTINEMKALNIEPSLGTYNHLLGVFYKGALSPRGQTEILSEVLDEIEGRSFTLRDPDDVYFFTNAMRVCLDLKDIELAYRLHALQQTADNRGLMGDFYLQSTYYGRFFNLLCMMENIDVILKWYRELIPSLYYPNSRGMLDLLQALDMDNCLDLIPQIWKDIKQIGHSNKVELVEEVLKLMARDVQPAELQAAFADTALDIKSLYEVRDRVRIVLEWSSASLGNISVLLARAGRTEEAWKMLQRFKTNHRVPSTEVVDEFLSRAKMDANTNLAISLVQLAVGFSLPNTGKLAERVMEEFNVSEEQRLTLEDLQKSHSSSSSSSESSDSDRE
What is the function of this protein?
Mitochondrial protein that may have a role in mitochondrial translation.
What are the official names of this protein?
Pentatricopeptide repeat domain-containing protein 3, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mS39 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MURA_ORITI
Sequence: MSSILVEGGKSLRGEINISGAKNAALPIIVASLLSSKTLVINNVPQLSDVSDMLFILKSCGVHVEIVESGTIALTANNISCHFSPPCNIVKKMRASIWILAPLLLRLGQVRIALPGGCAIGQRRIDLHLAALKAFGANIQLEEDYISANCSSRMHGISFKFDKVSVGATITAIMCAVLANGSTKLANCAQEPEIADLCYCLRKMGANITGIGTANISIIGVKELNGANYSIIPDRIEAGTYMVAAAITQGKIKLNNVIFKHLKSAITKLRLSGAIIQYQNENSLIIEGANIIKPLNIQTNPYPNFPTDLQAQFMSLMSIADGVSIITENIYENRYMHVFELIKMGANIVIQSREAIVTGVKKLHGADVIATDLRASVSLVLAGLSAAGITRVKRMHHLDRGYESLVEKLQNCNARVQRIPD
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNZ_THEKO
Sequence: MLEVFFLGTGGIMPTRERNVPAIALRYKGEIILFDAGEGTIRQMNTAKLSPMKVDKIFITHFHGDHYLGIPALIQTMNLWDRQKPLHIYGPKYTFQFVQNLLNSGFFRPGFDIHVHELGETRLKFGDYEIWSFKVEHGIPALGYVFKEKDRRGKFLKEKLREYGLEEGPILGKLEREGKIEWNGRIIRLEDVTGPRRKGLKIVYTGDTEPCERVKLFSERADLLIHEATYLNPGDRGDSYHSTVEEACDTARRAKVKLLALFHRAFRYSYEDYVEEALKICESLGVRAVVPRDFDVITFKSGTWELRNLLEERE
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: HBAT_PAPAN
Sequence: MALSAEDRALVRALWKKLGSNVGVYATEALERTFLAFPATKTYFSHLDLSPGSAQVRAHGQKVADALSLAVERLDDLPRALSALSHLHACQLRVDPANFPAPGPLPAGDPRPALPRRLQPGAAGVAGQVPEPRDLCAGFRVP
What are the official names of this protein?
Hemoglobin subunit theta-1, Hemoglobin theta-1 chain, Theta-1-globin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: METK_CHLSY
Sequence: MANTFMNSPRFYFTSESVSEGHPDKMCDQISDAILDAFLSHDPKARVAVETATTTGLIVVLGEVTYERGYIPIEEIVRRTVKEIGYTSAEYGFDADTCGVMVAIHGQSPDIAMGVDKALEAKIGAMADDVEAVGAGDQGMMFGFACDETPELMPASIALAHRLIRRLERVRKDGTLPYLRPDAKSQVTVEYSFGKPVRVDTVLISSQHAPDITQDQIRADLIEHVIKTEIPEAWLDSQTKIFINPTGRFVIGGPMGDSGLTGRKIIVDTYGGVARHGGGAFSGKDPSKVDRSAAYACRWVAKNIVAAGLARRVELQVSYAIGVARPLSLSVETFGTAAVPDEVILKAVNEVFDLRPGAIIRDLDLRRPIYRKTAAGGHFGRTDIDLPWERTNRVEELRRAAGL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MACB1_YERPN
Sequence: MTGPQQGKILLRLENVSREFITGEQTVRVLNNINLTLHSGEMVAIVGTSGSGKSTLMNILGCLDKPSAGEYWVAGRIPQYLGSDALAELRREHFGFIFQRYHLLNDLSARENVEIPAIYAGIDREERRKRAVNLLSRIGLAERLDYRPSQLSGGQQQRVSIARALMNGGDVILADEPTGALDTHSGNEVLNILKDLHQQGHTVVIVTHDMSIAEHAQRIIELKDGEIIADRPRDHAQEKPKMVDIPSVIDIPSMDEKISTGAQQETEIARKPLLTRWKVQYDRLHEAFKMAILAMAAQRLRTALTMLGIIIGIASVVSVVALGKGSQQQVLANINAMGTSTLEIFPGKDFGDMRSAAIHTLRDTDADVLAQQGYIHSVTPTVSTSVTLRYGNKSVSGTVNGVGEQYFLVRGYTIAQGMAFTRTSVNDLMQDAVIDENTRDKLFPNGETPLGKVILLGSLPCRVIGVAAKKQSGFGSDENLNVWIPYTTAMKRMLGQSYLKSITVRVNDDIDLANAEQGVIKLLSQRHGTQDFFVMNTDSIRQTIQATTSTMTLLVSMIAVISLIVGGIGVMNIMLVSVTERTKEIGVRMAVGARASDIMQQFLIEAVLVCLLGGSLGVALSLGIGLLFSLFSSNFSMVYSAASIITAFVCSSLIGVIFGFFPAKRAAEMDPIRALERE
What is the function of this protein?
Part of the tripartite efflux system MacAB-TolC.  MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation.  Confers resistance against macrolides.
What are the official names of this protein?
Macrolide export ATP-binding/permease protein MacB 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RECF_BACFN
Sequence: MILKRISILNYKNLEQVELNFSAKLNCFFGQNGMGKTNLLDAVYFLSFCKSAGNPIDSQNIRHEQDFFVIQGFYEAMDGTPEEIYCGMKRRSKKQFKRNKKEYSRLSDHIGFIPLVMVSPADSELIAGGSDERRRFMDVVISQYDKEYLDALIRYNKALVQRNTLLKSEQPIEEELFLVWEEMMAQAGEVVFRKREAFISEFIPIFQSFYSYISQDKEQVGLTYESHARKASLLEVLKESRVRDKIMGYSLRGIHKDELNMLLGDFPIKREGSQGQNKTYLVALKLAQFDFLKRTGSTVPLLLLDDIFDKLDASRVEQIVKLVAGDNFGQIFITDTNREHLDRILYKVGSDYKMFRVESGAINEMEEKER
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHMU_PSEAE
Sequence: MRPSFASWGLLALLLLQGPLLQAQPLSPALQQLLSLSSQRLQLADQVAQSKAQSGKAVQDSPREEQQLQMLAGQAGSHGVGAEQVRLLFAAQIEANKLVQYRLLSRPLPDAGQAVDLERIRSRLNQLNLELLRGYAPALAELRVDDCRPRLNQALQRQVRVDRLDELHAIALSRAAGDLCHWAEL
What is the function of this protein?
Catalyzes the Claisen rearrangement of chorismate to prephenate.  The joint presence of this enzyme together with cyclohexadienyl dehydratase and aromatic aminotransferase in the periplasmic compartment comprises a complete three-step chorismate to phenylalanine pathway and accounts for the so called hidden overflow pathway to phenylalanine in P. aeruginosa, in which two possible routes for it exists, namely either via phenylpyruvate or L-arogenate.
What are the official names of this protein?
Monofunctional chorismate mutase.
What are the subcellular locations of this protein?
Periplasm.
Protein: TRPA_MYCPA
Sequence: MTVKQSQASRLSPIFEPCRDDDRAALIGYLPTGYPDVPTSVQAMVALVESGCDIVEVGVPYSDPGMDGPTIARATEAALHGGVRVRDTLAAVEAISAAGGRAVVMTYWNPVLRYGVDAFARDLAAAGGYGLITPDLIPDEAGQWLAASERHGLDRIFLVAPSSTPQRLALTVEASRGFVYAASTMGVTGARDAVSHAAPELVSRVREISDIPVGVGLGVRSREQAAQIGGYADGVIVGSALVSALGDGGLTALRALTEELAAGVRQRAAAS
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: UBIE_BRUC2
Sequence: MSQQNGNVNRVGAQDRVGASGGMEHSFGFKAVDENEKQGLVNDVFHKVAKRYDIMNDLMSAGMHRVWKDAMVAWLAPSKRPGWTSLDVAGGTGDIAFRIVEVSGRQAHVTILDINGSMLGVGRERAIKKGLIDNLEFVEANAEELPFEDNSFDAYTIAFGIRNVPHIDKALSEAYRVLKPGGRFLCLEFSEVELPVLDKVYDEWSFRAIPRIGKMITGDADSYSYLVESIRKFPKQQDFAAMIEKAGFERVSYRNFTGGIAALHSGWKL
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: Y1510_DICDI
Sequence: MQTFSNINLVKPSRDWRVEKGDIDENNSGSINNRPLSPTLFSSNSSNNNNNNTTNNYIAVNGNLVLGVNGVGVGEQAQSLDIAVENPEECILWYYNYFLGKSHQNYLGTLDNGDVFGASIKKEEYAIEGEYSYKTIIWTLEGIERQWFQLKKHASTTPTDIIKKALPRLQIKKIKEIDSPDLLKDFKDLEQTQTEINYKFGLLLARPNQSSEDDFYNNVEHSPKWTEFLNLLGDTVVLNSFKGYRGGLDVNNNTTGTHSLYTSLKGYEVMFHVSTMLPHSKADSQQIERKRHLGNDIVIIIFYDCDPSDPIIPWDPSTVNSNFNHIFAVVRPADENNYHVEIVIKHGIAKFGPVLPTHSIFPKNSTFKEFLITKLVNAQRAALNSAPSFATKLKRTFKDQLESIYKKHSSSSSSLSFVPKRRSSSVSNINKGRELKVKDPKYGSGFFKLLSKDSNKTQVFDTEILFSKSLNEKINCLDVVESDENNSTLIVATEESIYLLKSNMITGEQLFQKIIVMKDVIRLTLVKPLKILLVLTGKGLCFFEMDTIFQQFNNLSTNSTIPSSYAIPIPTTPTTSNNNGGSGFFSSNNLSNGHTSLRWSKSGIIAAGLINNNNNSNSINSINSNNNNNINNSSINNNNGGNTNILAPSVFLSVNNNNNNSGNNIFNNNNNNNNNGGLNNSSENILTVIGEDSIKVKKIVGTKGCTVYGYTKGDNEGQEEDITLLYVGLKKTLLLYEWNKGEFVKSRELPLMDNIKTLCAIAPGMICVGIQKEFLLIDIFTQTIKELYKKSDSEPVKALSLDNEILLCFNNIGIFVDESGNKTRQFELKWGSTPSSLALVPSYVLGISGPLIEVRTLLNGNIIQSLPANISLSNDDCNLDNHYHHHEIINNCSAINIVNNQLSDNIENINNLNINNNNGNNNYNNNGNNSNGGNNNNNNNNNNGCNNSLINLDQETNNLMSENSNNGAENVYSFSTFNDIAHVDNGNIYVASSSKGLSCILRIKQNIQLNVLPSPSSSPLKPSLLLPPSPL
What are the official names of this protein?
GTPase-activating protein DDB_G0291510.
Protein: CH10_MYCGI
Sequence: MASVNIKPLEDKILVQANEAETTTASGLVIPDTAKEKPQEGTVVAVGPGRWDEDGEKRIPLDVSEGDVVIYSKYGGTEIKYNGEEYLILSARDVLAVVSK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIMT_HELPG
Sequence: MNSIKNHLMCEEIHKRFHLHPKVRKAMESIEREVFVPAPFKHFAYTLNALSMQAQQYISSPLTVAKMTQYLEIDHVDSVLEIGCGSGYQAAVLSQIFRRVFSVERIESLYLEARLRLKNLGLDNVHVKFADGNKGWEQYAPYDRILFSACAKNIPQALIDQLEEGGILVAPIQENNEQVIKRFVKQNNALRVQKVLEKCSFVPVIDGVQ
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROK2_RAT
Sequence: MEDPRCAPLLLLLLLPLLLTPPAGDAAVITGACDKDSQCGGGMCCAVSIWVKSIRICTPMGQVGDSCHPLTRKVPFWGRRMHHTCPCLPGLACLRTSFNRFICLARK
What is the function of this protein?
May function as an output molecule from the suprachiasmatic nucleus (SCN) that transmits behavioral circadian rhythm.  May also function locally within the SCN to synchronize output.  Potently contracts gastrointestinal (GI) smooth muscle (By similarity).
What are the official names of this protein?
Prokineticin-2, PK2.
What is the protein family that this protein belongs to?
Belongs to the AVIT (prokineticin) family.
What are the subcellular locations of this protein?
Secreted.
Protein: GLN1A_LACDE
Sequence: MSKVITEEEIRKDVEEKNVRFLRLAFTDINGTLKNLEVPVSQLDDVLGNQTRFDGSSIDGFVRLEESDMVLYPDLATWLVLAWTTVEEGTIGRLVCSVHNVDGTPFEGDPRNNLKKVIAEMEEMGFSDFEIGFEAEFFLFKEGKNGEETTKVSDHSSYFDMASEDEGAKCRREIVETLEKLGFRVEAAHHEVGDGQQEIDFRFDNALATADKLQTFKMVVKTIARKYHLHASFMAKPVEGLAGNGMHTNMSLLKDGKNAFYDKDGQYNLSTTALTFLNGILEHARAITCVANPTVNSYKRLIPGFEAPVYISWASRNRSPMVRIPNANEVGTRLEMRSTDPTANPYLLLSACLKAGLTGIKEGKLPMAPVTSNLFEMTDDERKELGIKPLPSTLHNAIKAFKEDEVVKSAFSEHIVDSFLELKETEWALYTQSVSEWEVKRYFNY
What is the function of this protein?
Glutamine synthetase (GS) is an unusual multitasking protein that functions as an enzyme, a transcription coregulator, and a chaperone in ammonium assimilation and in the regulation of genes involved in nitrogen metabolism.  It catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.  Feedback-inhibited GlnA also interacts with and regulates the activity of the transcriptional regulator TnrA.  During nitrogen limitation, TnrA is in its DNA-binding active state and turns on the transcription of genes required for nitrogen assimilation.  Under conditions of nitrogen excess, feedback-inhibited GlnA forms a stable complex with TnrA, which inhibits its DNA-binding activity.  In contrast, feedback-inhibited GlnA acts as a chaperone to stabilize the DNA-binding activity of GlnR, which represses the transcription of nitrogen assimilation genes.
What are the official names of this protein?
Glutamine synthetase, GS, Glutamate--ammonia ligase, Glutamine synthetase I alpha, GSI alpha.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM2_CHLP8
Sequence: MSQLDLLNIVHRPRRLRRTAALRNLVQENTLTVNDLVFPLFVMPGTNAVEEVSSMPGSFRFTIDRAVEECKELYDLGIQGIDLFGIPEQKTEDGSEAYNDNGILQQAIRAIKKAVPELCIMTDVALDPFTPFGHDGLVKDGIILNDETVEVLQKMAVSHAEAGADFVSPSDMMDGRIGAIREALDETDHSDVGILSYAAKYASSFYGPFRDALHSAPQFGDKSTYQMNPANTEEAMKEVELDIVEGADIVMVKPGLAYLDIVWRTKERFDVPVAIYHVSGEYAMVKAAAAKGWIDEDRVMMESLLCMKRAGADIIFTYYAKEAAKKLR
What is the function of this protein?
Catalyzes an early step in the biosynthesis of tetrapyrroles.  Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
What are the official names of this protein?
Delta-aminolevulinic acid dehydratase, ALAD, ALADH, Porphobilinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the ALAD family.
Protein: PRTN_PSEAE
Sequence: MQPSIAPSTPIPRQETVELVYRIFGDVLVPLEQVRERWFRNLNKENFSKALACGRIALPVTTLDDSHKAMQFVALDHLAAYVDQRANQAGSARRAQPGADSIAS
What is the function of this protein?
Activates pyocin genes, probably by binding to the sequences conserved in their 5' non-coding regions (P box).
What are the official names of this protein?
Transcription regulatory protein PrtN, Pyocin activator protein.
Protein: AES_ECOLC
Sequence: MKPENKSPVLDLISAGMKTVVNTLQPDLPPWPATGTIAEQRQYYTLERRFWNAGAPEMATRAYMVPTKYGQVETRLFCPQPDSPATLFYLHGGGFILGNLDTHDRIMRVLASYSQCTVIGIDYTLSPEARFPQAIEEIVAACCYFHQQAEDYQINMSRIGFAGDSAGAMLALASALWLRDKQIDCGKIAGVLLWYGLYGLRDSVTRRLLGGVWDGLTQQDLQMYEEAYLSNDADRESPYYCLFNNDLTREVPPCFIAGAEFDPLLDDSRLLYQTLAAHQQPCEFKLYPGTLHAFLHYSRMMKTADEALRDGAQFFTAQL
What is the function of this protein?
Displays esterase activity towards short chain fatty esters (acyl chain length of up to 8 carbons).  Able to hydrolyze triacetylglycerol (triacetin) and tributyrylglycerol (tributyrin), but not trioleylglycerol (triolein) or cholesterol oleate.  Negatively regulates MalT activity by antagonizing maltotriose binding.  Inhibits MelA galactosidase activity.
What are the official names of this protein?
Acetyl esterase.
What is the protein family that this protein belongs to?
Belongs to the 'GDXG' lipolytic enzyme family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACDB2_METTE
Sequence: MSEFPFEISPMFEGERVRKEGMFVELGGPKSLGLELVRAKPMDEIEDGKVTIVGPDLKDMEEGKTYPWAMIFHVGGELVEPDLESVIERRVHDFINYCQGIMHLNQRYDVWMRISKDTAAKMDSFEPFGKAVMMLFKTELPFIEKMQVTFYTDQAEVEKQMAEAMEIFKARDARTKDLHDEDVDVFYGCTLCQSFAPTNVCVVSPDRVSLCGAINWFDGRAAAKVDPEGPQFAIEKGELLDAKTGEYSGVNEVAKKLSSGEFDKIKLHSFFDAPHTSCGCFEDVGFYIPEVDGIGWVNREYQGMAPNGLGFSTMAGQTGGGKQIVGFLGIGINYFYSPKFIQADGGWNRVVWLPSMLKEKIDEAIPDDMKDKIATEKDVTDIESLKTFLKEKNHPVVANWAAEAEEEEEEEGEEEEVAAEAAPMMMPAAGFQMPAMPAMPMMSGGAGGIKLTFKNAKITIDRMIISEKKEKK
What is the function of this protein?
Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy.  The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA.  The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex).
What are the official names of this protein?
Acetyl-CoA decarbonylase/synthase complex subunit beta 2, ACDS complex subunit beta 2, ACDS complex acyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the CdhC family.
Protein: DNAJ_SALRD
Sequence: MPRDYYDILGVDEDASDKEIKKAYRKKAMEYHPDRNPDDPEAEQKFKEASEAYEVLSDPEKRQRYDQFGHDGVDSGAGGGRRGRGRGFHDIEDIFDAFSDIFGGAPGGGRGRGRSERGRGRPGSDLRVSLSLTLEEIAEGTEKNLRLQKYLECESCDGTGAEGGMGGQNFSMCPKCDGTGEIRQVSRSVFGQVVNVQPCPRCEGEGRIIDNLCDDCGGEGRVQGEESISINVPPGVMEGNYLTLGDAGNAGLRGGPSGDLRIEIEEEPHEHFERDGLDIYYDLHLSFPEAALGTEVDVPTLEGEARLEVDPGVQAGKILRMRDRGLPDLEGSGQGDQMIRVHVWTPQELTAEEEELLDQLRAHDNFQPRPPEEDTQKSFFRRVSDVFS
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.