PharMolix/UniProtQA huggingface dataset:
Protein: PLSB_SALTY
Sequence: MSGWPRIYYKLLNLPLSILVKSKSIPAEPAQELGLDTSRPIMYVLPYNSKADLLTLRAQCLAHDLPDPLEPLEIDGALLPRYVFIHGGPRVFTYYTPKEESVKLFHDYLDLHRSNPALDVQMVPVSVMFGRAPGREKGEDNPPLRMLNGVQKFFAISWLGRDSFVRFSPSVSLRRMADEHGTDKIIAQKLARVARMHFARQRLAAVGPRLPARQDLFNKLLASKAIARAVEDEARSKKISHEKAQQNAIALMEEIAANFSYEMIRLTDRILGFTWNRLYQGINVHNAERVRQLAHDGHEIVYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFSRGYSVEYFVEGGRSRTGRLLDPKTGTLSMTIQAMLRGGTRPITLVPIYIGYEHVMEVGTYAKELRGATKEKESLPQMLKGLSKLRNLGQGYVNFGEPMPLMTYLNQHVPEWRESIDPIEAIRPAWLTPTVNSIAADLMVRINNAGAANAMNLCCTALLASRQRSLTREQLTEQLDCYLDLMRNVPYSTDSTVPAASAGELIAHALQMNKFEVEKDTIGDIIILPREQAVLMTYYRNNIAHMLIMPSLMAAIITQHRRISRDALQQHVEALYPMLKAELFLRWEREELASVIDALASEMQRQGLITLQDDELHINPTHSRTLQLLAAGARETLQRYAITFWLLSANPSINRSTLEKESRTVAQRLSVLHGINAPEFFDKAVFSSLVLTLRDEGYISDTGDAEPAETMKIYQMLADLITSDVRLTIESATQGE
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, GPAT.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YO08_BPL2
Sequence: MMKKYMIERDNKFFSSFGNDFDKKGRQKLKPIYSLKQNAVYFSSLSDAQITASRVQGKVIEIKG
What are the official names of this protein?
Uncharacterized 7.3 kDa protein, ORF8.
Protein: CAS1_METJA
Sequence: MRKKSLTLLSDGYLFRKENTIYFENARGKKPLAIEGIYDIYIYGKVSISSQALHYLAQKGIALHFFNHYGYYDGSFYPRESLHSGYLVVNQVEHYLDKDKRLELAKLFIIGGIKNMEWNLLKFKNKTKFSSYIEELNNCNKITEVMNVEGRVRTEYYRLWDETLPDDFKIVKRTRRPPKNEMNALISFLNSRLYPAIITELYNTQLTPTVSYLHEPHERRFSLALDLSEIFKPMIADRLANRLVKQGIIQKKHFRDDLNGVLLNKEGMKVVLEHFNKEMDKTVNHKKLKKNVSKRRLIRLEAYKLVKHLVGQKRYEPLVAWF
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Acts as a dsDNA endonuclease.  Involved in the integration of spacer DNA into the CRISPR cassette.
What are the official names of this protein?
CRISPR-associated endonuclease Cas1.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endonuclease Cas1 family.
Protein: RPA1_HUMAN
Sequence: MLISKNMPWRRLQGISFGMYSAEELKKLSVKSITNPRYLDSLGNPSANGLYDLALGPADSKEVCSTCVQDFSNCSGHLGHIELPLTVYNPLLFDKLYLLLRGSCLNCHMLTCPRAVIHLLLCQLRVLEVGALQAVYELERILNRFLEENPDPSASEIREELEQYTTEIVQNNLLGSQGAHVKNVCESKSKLIALFWKAHMNAKRCPHCKTGRSVVRKEHNSKLTITFPAMVHRTAGQKDSEPLGIEEAQIGKRGYLTPTSAREHLSALWKNEGFFLNYLFSGMDDDGMESRFNPSVFFLDFLVVPPSRYRPVSRLGDQMFTNGQTVNLQAVMKDVVLIRKLLALMAQEQKLPEEVATPTTDEEKDSLIAIDRSFLSTLPGQSLIDKLYNIWIRLQSHVNIVFDSEMDKLMMDKYPGIRQILEKKEGLFRKHMMGKRVDYAARSVICPDMYINTNEIGIPMVFATKLTYPQPVTPWNVQELRQAVINGPNVHPGASMVINEDGSRTALSAVDMTQREAVAKQLLTPATGAPKPQGTKIVCRHVKNGDILLLNRQPTLHRPSIQAHRARILPEEKVLRLHYANCKAYNADFDGDEMNAHFPQSELGRAEAYVLACTDQQYLVPKDGQPLAGLIQDHMVSGASMTTRGCFFTREHYMELVYRGLTDKVGRVKLLSPSILKPFPLWTGKQVVSTLLINIIPEDHIPLNLSGKAKITGKAWVKETPRSVPGFNPDSMCESQVIIREGELLCGVLDKAHYGSSAYGLVHCCYEIYGGETSGKVLTCLARLFTAYLQLYRGFTLGVEDILVKPKADVKRQRIIEESTHCGPQAVRAALNLPEAASYDEVRGKWQDAHLGKDQRDFNMIDLKFKEEVNHYSNEINKACMPFGLHRQFPENSLQMMVQSGAKGSTVNTMQISCLLGQIELEGRRPPLMASGKSLPCFEPYEFTPRAGGFVTGRFLTGIKPPEFFFHCMAGREGLVDTAVKTSRSGYLQRCIIKHLEGLVVQYDLTVRDSDGSVVQFLYGEDGLDIPKTQFLQPKQFPFLASNYEVIMKSQHLHEVLSRADPKKALHHFRAIKKWQSKHPNTLLRRGAFLSYSQKIQEAVKALKLESENRNGRSPGTQEMLRMWYELDEESRRKYQKKAAACPDPSLSVWRPDIYFASVSETFETKVDDYSQEWAAQTEKSYEKSELSLDRLRTLLQLKWQRSLCEPGEAVGLLAAQSIGEPSTQMTLNTFHFAGRGEMNVTLGIPRLREILMVASANIKTPMMSVPVLNTKKALKRVKSLKKQLTRVCLGEVLQKIDVQESFCMEEKQNKFQVYQLRFQFLPHAYYQQEKCLRPEDILRFMETRFFKLLMESIKKKNNKASAFRNVNTRRATQRDLDNAGELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEEEREGEENDDEDMQEERNPHREGARKTQEQDEEVGLGTEEDPSLPALLTQPRKPTHSQEPQGPEAMERRVQAVREIHPFIDDYQYDTEESLWCQVTVKLPLMKINFDMSSLVVSLAHGAVIYATKGITRCLLNETTNNKNEKELVLNTEGINLPELFKYAEVLDLRRLYSNDIHAIANTYGIEAALRVIEKEIKDVFAVYGIAVDPRHLSLVADYMCFEGVYKPLNRFGIRSNSSPLQQMTFETSFQFLKQATMLGSHDELRSPSACLVVGKVVRGGTGLFELKQPLR
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Largest and catalytic core component of RNA polymerase I which synthesizes ribosomal RNA precursors.  Forms the polymerase active center together with the second largest subunit.  A single stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol I.  A bridging helix emanates from RPA1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol I by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase I subunit RPA1, RNA polymerase I subunit A1, A190, DNA-directed RNA polymerase I largest subunit, DNA-directed RNA polymerase I subunit A, RNA polymerase I 194 kDa subunit, RPA194.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Chromosome.
Protein: RS12_CYTH3
Sequence: MPTIQQLVRKGREQLVFKSKSPALDSCPQRRGVCTRVYTTTPKKPNSAMRKVARVRLTNSKEVNAYIPGEGHNLQEHSIVLIRGGRVKDLPGVRYHIVRGALDTAGVNGRKQSRSKYGAKRPKPGQAAAAPAKGKKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: STE12_YEAST
Sequence: MKVQITNSRTEEILKVQANNENDEVSKATPGEVEESLRLIGDLKFFLATAPVNWQENQIIRRYYLNSGQGFVSCVFWNNLYYITGTDIVKCCLYRMQKFGREVVQKKKFEEGIFSDLRNLKCGIDATLEQPKSEFLSFLFRNMCLKTQKKQKVFFWFSVAHDKLFADALERDLKRESLNQPSTTKPVNEPALSFSYDSSSDKPLYDQLLQHLDSRRPSSTTKSDNSPPKLESENFKDNELVTVTNQPLLGVGLMDDDAPESPSQINDFIPQKLIIEPNTLELNGLTEETPHDLPKNTAKGRDEEDFPLDYFPVSVEYPTEENAFDPFPPQAFTPAAPSMPISYDNVNERDSMPVNSLLNRYPYQLSVAPTFPVPPSSSRQHFMTNRDFYSSNNNKEKLVSPSDPTSYMKYDEPVMDFDESRPNENCTNAKSHNSGQQTKQHQLYSNNFQQSYPNGMVPGYYPKMPYNPMGGDPLLDQAFYGADDFFFPPEGCDNNMLYPQTATSWNVLPPQAMQPAPTYVGRPYTPNYRSTPGSAMFPYMQSSNSMQWNTAVSPYSSRAPSTTAKNYPPSTFYSQNINQYPRRRTVGMKSSQGNVPTGNKQSVGKSAKISKPLHIKTSAYQKQYKINLETKARPSAGDEDSAHPDKNKEISMPTPDSNTLVVQSEEGGAHSLEVDTNRRSDKNLPDAT
What is the function of this protein?
Binds to the DNA sequence mediating pheromone induction (called the pheromone response element = PRE) which is found in the upstream control region of several a-, alpha- and haploid-specific genes.  Involved in mating of haploids and in pseudohyphae formation in diploids.
What are the official names of this protein?
Protein STE12.
What is the protein family that this protein belongs to?
Belongs to the STE12 transcription factor family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LUXS_SALCH
Sequence: MPLLDSFAVDHTRMQAPAVRVAKTMNTPHGDAITVFDLRFCIPNKEVMPEKGIHTLEHLFAGFMRDHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVADAWKAAMADVLKVQDQNQIPELNVYQCGTYQMHSLSEAQDIARHILERDVRVNSNKELALPKEKLQELHI
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: NUOB_RUEST
Sequence: MAGANTAGVDKEMVTQALNAELQDKGFLLTSAEDIINWARTGSLHWMTFGLACCAVEMMHTSMPRYDAERFGIAPRASPRQSDVMIVAGTLTNKMAPALRKVYDQMPEPRYVISMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGLMQLQRKIRRTGTLVR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PG087_VACCC
Sequence: MPFRDLILFNLSKFLLTEDEESLEIVSSLCRGFEISYDDLITYFPDRKYHKYISKVFEHVDLSEELSMEFHDTTLRDLVYLRLYKYSKCIRPCYKLGDNLKGIVVIKDRNIYIREANDDLIEYLLKEYTPQIYTYSNERVPITGSKLILCGFSQVTFMAYTTSHITTNKKVDVLVSKKCIDELVDPINYQILQNLFDKGSGTINKILRKIFYSVTGGQTP
What is the function of this protein?
Involved in postreplicative transcription elongation on intermediate and late genes.
What are the official names of this protein?
Late transcription elongation factor OPG087, Late transcription elongation factor G2, Protein G2.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG087 family.
Protein: LYOPH_LYOSH
Sequence: ITFQGCSPARQTVITNAITRARADVRAAVSALPTKAPVSTFSTWFGVYND
What is the function of this protein?
N-glycosylase that inhibits protein synthesis by depurinating ribosomal rRNA, and thus acts as a ribosomal inactivating protein (RIP) (PubMed:34769028, PubMed:11556814).  Has adenine polynucleotide glycosidase activity on the poly(A) substrate A30-ssDNA (PubMed:11556814).  Inhibits cell-free translation in rabbit reticulocyte lysate system with an IC(50) of 1 nM (PubMed:11556814, PubMed:34769028).  May function in the defense response to pathogens (PubMed:11556814).  Displays antifungal activity against C. comatus and P. piricola, but not against R. solani, M. arachidicola and C. gossypii (PubMed:11556814).  Inhibits mycelial growth in P. piricola with an IC(50) of 2. 5 uM (PubMed:11556814).  Has cytotoxic activity against the human cancer cell lines Hela, HepG2, and JAR, with IC(50) of 358. 8, 489. 8, and 926. 9 nM respectively (PubMed:34769028).  It also inhibits HIV-1 reverse transcriptase activity (IC(50)=7. 9 nM) and disrupts mouse embryonic development (PubMed:11556814, PubMed:19568748).
What are the official names of this protein?
Ribosome-inactivating protein lyophyllin.
Protein: HTPX_POLNA
Sequence: MKRILLFILTNVAVVAVLGIVASLLGVNRFLTANGLNLSALLGFALIMGFGGAIISLLISKPVAKWSAGVRLINDPQNADEAWIVETVRRLADKAQIGMPEVGIFEGEPNAFATGAFKNSSLVAVSTGLLQGMTKEEIEAVLGHEIAHVANGDMVTMTLIQGVMNTFVVFLSRVIGYAVDSFLRKGDSNSSGPGIGYYVSTIVLDIVLGFAAAIVVAWFSRHREFRADAGAAQLMGRKQPMMNALARLGGMQPGELPKAVEAMGITGSIGKLFATHPPIEERIAALQNAQG
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CRTK_RHOCB
Sequence: MSLTLFAVYFVACACAGATGAIFSPGAWYDSLKKPSWVPPNWLFPVAWSTLYILMSISAARVSGLAMENELAVLGLAFWAVQIAVNTLWTPIFFGLHRLAGGMLVLVLLWLSVFATCVLFWSVDWLSGLMFVPYVIWVTVAGALNFSVWRLNPGEKPITL
What are the official names of this protein?
Protein CrtK.
What is the protein family that this protein belongs to?
Belongs to the TspO/BZRP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DOMT1_SINHE
Sequence: MDTRADAEIKAMELIGIGVLPLAMKAIIELNVLEILSKAGPDTQLTAAQIVTDIPTTNPNAGFQLDRILRLLASHSVLSSSITKSGERVYGLTPMCKYFLPDQDGVSLAPMVVTIHDKVLLQSWHYLKDSVLKQGSLPFTEAFGMSPFEYSVSDTRFNKVFNAGMFDHSTLCMRDVLQRYKGFQGLGELVDVGGGTGGSLKMILSQYPNLKGINFDLPHVVADAPSFPGVKHIGGDMFESVPSGDAIFMKWILHDWDDGRCLTLLKNCWNALPEHGKVIIVEWILPSDAATDPTSRRVFTADLMMLAFSEGGKERTLGDYGALAKEAGFTTVKDFPCANGISVIEFHKK
What is the function of this protein?
O-methyltransferase involved in the biosynthesis of etoposide, a chemotherapeutic compound of the topoisomerase inhibitor family (PubMed:26359402).  Catalyzes the methylation of (-)-5'-demethylyatein to produce (-)-yatein (PubMed:26359402).
What are the official names of this protein?
Desmethyl-yatein O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. COMT subfamily.
Protein: BCLTS_ALKCL
Sequence: MGTVPANPFKIIQLAFKETVPKAHAELQKWHQEALKIEDVEIREQAAWTVNDKTFHCEGGSIFALLAGENKDNHIQFLVAYQTICDYLDTLCDKNDAHDPNDFRSIHQALLDCLTPDKPYGDYYQYRDRFEDNGYLRKLVDACREATASFPGFADMQTHMQEVSQFYIDFQVYKHVEEEKREPLLKDFYERNKHFAPTMRWYEFACGTASTLALYCMAAYAAAPVQTAQGQQIKEAYFTWVQGVHILLDYFIDQEEDRQENEMNFVAYYRDSKEMFERFKYIDEKATEKLQMLPDKKFHLLLKTGLYALYLSDKKVMSHPRLKAEAKQLIKLGGFPASLFYYNRWIFKRKIS
What is the function of this protein?
Catalyzes the conversion of geranylfarnesyl diphosphate (GFPP) and hexaprenyl diphosphate (HexPP) into beta-geranylfarnesene and beta-hexaprene, respectively (PubMed:23554321, PubMed:25882275).  Also produces beta-heptaprene from heptaprenyl diphosphate (HepPP) as a minor product (PubMed:25882275).
What are the official names of this protein?
Trifunctional sesterterpene/triterpene/sesquarterpene synthase, Bcl-TS, Beta-geranylfarnesene synthase.
What is the protein family that this protein belongs to?
Belongs to the large terpene synthase family.
Protein: PTGDS_PONPY
Sequence: MATHHTLWMGLALLGVLGGLQAAPEAQVSVQPNFQQDKFLGRWFSAGLASNSSWLREKKAALSMCKSVVAPAADGGLNLTSTFLRKNQCETRTMLLQPAGSLGSYSYRSPHWGSTYSVSVVETDYDQYALLYSQGSKGPGEDFRMATLYSRTQTPRAELKEKFTAFCKAQGFTEDTIVFLPQTDKCMTEQ
What is the function of this protein?
Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation.  Involved in a variety of CNS functions, such as sedation, NREM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes.  Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophobic molecules and as a secretory retinoid and thyroid hormone transporter.  Possibly involved in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier.  It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system (By similarity).  Involved in PLA2G3-dependent maturation of mast cells.  PLA2G3 is secreted by immature mast cells and acts on nearby fibroblasts upstream to PTDGS to synthesize PGD2, which in turn promotes mast cell maturation and degranulation via PTGDR (By similarity).
What are the official names of this protein?
Prostaglandin-H2 D-isomerase, Glutathione-independent PGD synthase, Lipocalin-type prostaglandin-D synthase, Prostaglandin-D2 synthase, PGD2 synthase, PGDS, PGDS2.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Rough endoplasmic reticulum. Nucleus membrane. Golgi apparatus. Cytoplasm, perinuclear region. Secreted. Note=Detected on rough endoplasmic reticulum of arachnoid and menigioma cells. Localized to the nuclear envelope, Golgi apparatus, secretory vesicles and spherical cytoplasmic structures in arachnoid trabecular cells, and to circular cytoplasmic structures in meningeal macrophages and perivascular microglial cells. In oligodendrocytes, localized to the rough endoplasmic reticulum and nuclear envelope. In retinal pigment epithelial cells, localized to distinct cytoplasmic domains including the perinuclear region. Also secreted.
Protein: AROA_METPE
Sequence: MDQTLQQHGPVDLAFTAPPSKSFTHRALIIAALADGESLIRGPLIAEDTLLTVRALQALGADITDTPEGYRVQGTDGRPDCAEGTVLDLKNSGTSLRLLSSIALLCSSTAGVTLTGSPRMQQRPIGELGDAIRTLGGSVRYLAADGYPPCVVQGPLVGGEATLDGSVSSQFISSLLLAAPYAVRPVDLKVARQPVSRSYLEITGAVMAAFGVPVRRVGYTHFTVQPARYRGREYTVEGDYSSASYFFALAATLGGKVTVRNLNHDSVQGDRLFVAALKAMGCRVTRETDGVTIERTKNLHGISIDMTTAPDTVQTLAVVAALADSPTTITGVGHLQYKESDRVAVTAGTLRALGCTVDISADAITIHPGPLHGGVIDPHDDHRTAMAFAVLGLAVGDVTIEDPACVGKSFPKFWNALAAGGLL
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHYDA_ECOLI
Sequence: MRVLIKNGTVVNADGQAKQDLLIESGIVRQLGNNISPQLPYEEIDATGCYVFPGGVDVHTHFNIDVGIARSCDDFFTGTRAAACGGTTTIIDHMGFGPNGCRLRHQLEVYRGYAAHKAVIDYSFHGVIQHINHAILDEIPMIVEEGLSSFKLYLTYQYKLNDDEVLQALRRLHESGALTTVHPENDAAIASKRAEFIAAGLTAPRYHALSRPLECEAEAIARMINLAQIAGNAPLYIVHLSNGLGLDYLRLARANHQPVWVETCPQYLLLDERSYDTEDGMKFILSPPLRNVREQDKLWCGISDGAIDVVATDHCTFSMAQRLQISKGDFSRCPNGLPGVENRMQLLFSSGVMTGRITPERFVELTSAMPARLFGLWPQKGLLAPGSDGDVVIIDPRQSQQIQHRHLHDNADYSPWEGFTCQGAIVRTLSRGETIFCDGTFTGKAGRGRFLRRKPFVPPVL
What is the function of this protein?
Catalyzes the stereospecific hydrolysis of the cyclic amide bond of D-hydantoin derivatives with an aromatic side chains at the 5'-position.  Has no activity on dihydropyrimidines.  The physiological function is unknown.
What are the official names of this protein?
D-phenylhydantoinase, Hydantoin-utilizing enzyme HyuA.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
Protein: ARR1_ARATH
Sequence: MMNPSHGRGLGSAGGSSSGRNQGGGGETVVEMFPSGLRVLVVDDDPTCLMILERMLRTCLYEVTKCNRAEMALSLLRKNKHGFDIVISDVHMPDMDGFKLLEHVGLEMDLPVIMMSADDSKSVVLKGVTHGAVDYLIKPVRMEALKNIWQHVVRKRRSEWSVPEHSGSIEETGERQQQQHRGGGGGAAVSGGEDAVDDNSSSVNEGNNWRSSSRKRKDEEGEEQGDDKDEDASNLKKPRVVWSVELHQQFVAAVNQLGVEKAVPKKILELMNVPGLTRENVASHLQKYRIYLRRLGGVSQHQGNLNNSFMTGQDASFGPLSTLNGFDLQALAVTGQLPAQSLAQLQAAGLGRPAMVSKSGLPVSSIVDERSIFSFDNTKTRFGEGLGHHGQQPQQQPQMNLLHGVPTGLQQQLPMGNRMSIQQQIAAVRAGNSVQNNGMLMPLAGQQSLPRGPPPMLTSSQSSIRQPMLSNRISERSGFSGRNNIPESSRVLPTSYTNLTTQHSSSSMPYNNFQPELPVNSFPLASAPGISVPVRKATSYQEEVNSSEAGFTTPSYDMFTTRQNDWDLRNIGIAFDSHQDSESAAFSASEAYSSSSMSRHNTTVAATEHGRNHQQPPSGMVQHHQVYADGNGGSVRVKSERVATDTATMAFHEQYSNQEDLMSALLKQEGIAPVDGEFDFDAYSIDNIPV
What is the function of this protein?
Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3'.  Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system.  Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes.  Could directly activate some type-A response regulators in response to cytokinins.  Regulates SHY2 by binding to its promoter (PubMed:19039136).  Involved in the root-meristem size determination through the regulation of cell differentiation (PubMed:17363254).
What are the official names of this protein?
Two-component response regulator ARR1.
What is the protein family that this protein belongs to?
Belongs to the ARR family. Type-B subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: NU4C_AMBTC
Sequence: MNNFPWLTAILLLPISAGSSILFIPQRGNKAVRWYTICICLLELLLMTYVFYYNFQLDDPLIQLEEDCNWINLFDFHWRLGIDGLSIGPILLTGFITTLATSAAWPVTRNSRLFHFLMLAMYSGQIGSFSSRDLLLFFIMWELELIPVYLLLSMWGGKKRLYSATKFILYTAGGSIFLLIGVLGMGLYSSNQPMLNFETSANQSYPVGLEILFYFGFLIAYAAKPPIIPLHTWLPDTHGEAHYSTCMLLAGILLKMGAYGLVRINMELLPHAHSLFSPWLVIVGTLQIIYAASTSLGQRNLKKRIAYSSVSHMGSTIIGIGSMTDTALNGAILQIISHGFIGAALFFLAGTSYDRIRFLYLDEMGGIAIPMPKIFTMFSIFSMASLASPGMSGFVAEFLVFLGIITSPKYLFIPKILITVVMAIGMILTPIYLLSMSRQMFYGYKLFNVPNSYFVDSGPREIFILISILLPVMGIGIYPDFVLSLSVDKVEAILANYFNG
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase chain 4, chloroplastic, NAD(P)H dehydrogenase, chain 4, NADH-plastoquinone oxidoreductase chain 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RS13_METRJ
Sequence: MARIAGVNIPTNKRVVIALQYIHGIGAKKAEEITQKVNIPAERRVNQLTDAEVLQIRETIDRDYLVEGDLRREVSMNIKRLMDLGAYRGLRHRKQLPVRGQRTHTNARTRKGKAKPIAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: YIHI_CROS8
Sequence: MKQPSSSVRGKGPAKAKARRKTREELNQEARDRKRDKKHRGHAPGSRATGASASGKSSGQSTQKDPRIGSKKPIPLGVSDAQETRPQKHQPQPKSEKPMLSPQEELDMLENDERLDALLERLEEGETLSADDQAWVDSRLDRIDELMQQLGLSYDDEEDEEEEQQEDMMRLLKGGN
What is the function of this protein?
A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function.  May play a role in ribosome biogenesis.
What are the official names of this protein?
Der GTPase-activating protein YihI.
What is the protein family that this protein belongs to?
Belongs to the YihI family.
Protein: TOLB_HELPJ
Sequence: MKYLWLFLIYAIGLFATDKTLDIIKTIQKLPKIEVRYSIDNDANYALKLHEVLANDLKTSQHFDVSQNKEQGAINYAELKDKKVHLVALVSVAVENGNKISRLKLYDVDTGTLKKTFDYPIVSLDLYPFAAHNMAIVVNDYLKAPSIAWMKRLIVFSKYIGPGITNIALADYTMRYQKEIIKNNRLNIFPKWANAEQTEFYYTQYGEKTPMILKYNIQKATHENIASSQGMAVVSSVSSDGSKILMSLAPDGQPDVYLYDTHKKTKTKITRYPGIDVSGVFLEDDKSMAFVSDRSGYPNIYMKKLGLKESAEQLLYEGRSNESIDAYKDSIVYVSRENLNEFGKTVFNLNLIALNSKYIRRLTVNGSNQMPRFSMDGRNIMYIKKTSQEYAMGLILLDYNQSFLFPLKNVKIQAFDW
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RL11_THEON
Sequence: MPQVVEVLVEGGKASPGPPLGPAIGPLGLNVKQVVDEINKATKDFEGMQVPVKIIVEDPKKKTFRIEVGVPPVSQLIKKELGIPKGSSEAGHSPVGNLTMEQVIRIAKAKMDQMLAADLKAAAKEVIGTALSMGVTVEGKDPREVQKEIDEGVYDEIFANAEE
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RL5_LEUMM
Sequence: MANALKEKYVNEVQPALIEKFNFKSSMQAPKIDKIVLNMGVGDAVSNSKNLDEAVEELKLIAGQQPVITKAKKSIAGFRLREGMSIGTKVTLRGERMYDFLDKLINISLPRVRDFRGVSSKAFDGRGNYTLGIREQLIFPEIDFDKVNRVRGLDIVIVTTAQNDEEGRELLTQMGMPFAK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.