PharMolix/UniProtQA huggingface dataset:
Protein: ZMPB_STRPN
Sequence: MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEIISQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKKIASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMEGYRYVGYLSGDILKTLGLDTVLEETSAKPGEVTVVEVETPQSITNQEQARTENQVVETEEAPKEEAPKTEESPKEEPKSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPAEESKVEQAGEPVAPREDEKAPVEPEKQPEAPEEEKAVEETPKQEESTPDTKAEETVEPKEETVNQSIEQPKVETPAVEKQTEPTEEPKVEQAGEPVAPREDEQAPTAPVEPEKQPEVPEEEKAVEETPKPEDKIKGIGTKEPVDKSELNNQIDKASSVSPTDYSTASYNALGPVLETAKGVYASEPVKQPEVNSETNKLKTAIDALNVDKTELNNTIADAKTKVKEHYSDRSWQNLQTEVTKAEKVAANTDAKQSEVNEAVEKLTATIEKLVELSEKPILTLTSTDKKILEREAVAKYTLENQNKTKIKSITAELKKGEEVINTVVLTDDKVTTETISAAFKNLEYYKEYTLSTTMIYDRGNGEETETLENQNIQLDLKKVELKNIKRTDLIKYENGKETNESLITTIPDDKSNYYLKITSNNQKTTLLAVKNIEETTVNGTPVYKVTAIADNLVSRTADNKFEEEYVHYIEKPKVHEDNVYYNFKELVEAIQNDPSKEYRLGQSMSARNVVPNGKSYITKEFTGKLLSSEGKQFAITELEHPLFNVITNATINNVNFENVEIERSGQDNIASLANTMKGSSVITNVKITGTLSGRNNVAGFVNNMNDGTRIENVAFFGKLHSTSGNGSHTGGIAGTNYRGIVRKAYVDATITGNKTRASLLVPKVDYGLTLDHLIGTKALLTESVVKGKIDVSNPVEVGAIASKTWPVGTVSNSVSYAKIIRGEELFGSNDVDDSDYASAHIKDLYAVEGYSSGNRSFRKSKTFTKLTKEQADAKVTTFNITADKLESDLSPLAKLNEEKAYSSIQDYNAEYNQAYKNLEKLIPFYNKDYIVYQGNKLNKEHHLNTKEVLSVTAMNNNEFITNLDEANKIIVHYADGTKDYFNLSSSSEGLSNVKEYTITDLGIKYTPNIVQKDNTTLVNDIKSILESVELQSQTMYQHLNRLGDYRVNAIKDLYLEESFTDVKENLTNLITKLVQNEEHQLNDSPAARQMIRDKVEKNKAALLLGLTYLNRYYGVKFGDVNIKELMLFKPDFYGEKVSVLDRLIEIGSKENNIKGSRTFDAFGQVLAKYTKSGNLDAFLNYNRQLFTNIDNMNDWFIDATEDHVYIAERASEVEEIKNSKHRAFDNLKRSHLRNTILPLLNIDKAHLYLISNYNAIAFGSAERLGKKSLEDIKDIVNKAADGYRNYYDFWYRLASDNVKQRLLRDAVIPIWEGYNAPGGWVEKYGRYNTDKVYTPLREFFGPMDKYYNYNGTGAYAAIYPNSDDIRTDVKYVHLEMVGEYGISVYTHETTHVNDRAIYLGGFGHREGTDAEAYAQGMLQTPVTGSGFDEFGSLGINMVFKRKNDGNQWYITDPKTLKTREDINRYMKGYNDTLTLLDEIEAESVISQQNKDLNSAWFKKIDREYRDNNKLNQWDKIRNLSQEEKNELNIQSVNDLVDQQLMTNRNPGNGIYKPEAISYNDQSPYVGVRMMTGIYGGNTSKGAPGAVSFKHNAFRLWGYYGYENGFLGYASNKYKQQSKTDGESVLSDEYIIKKISNNTFNTIEEFKKAYFKEVKDKATKGLTTFEVNGSSVSSYDDLLTLFKEAVKKDAETLKQEANGNKTVSMNNTVKLKEAVYKKLLQQTNSFKTSIFK
What is the function of this protein?
Is a virulence factor capable of inducing inflammation in the lower respiratory tract, by increasing tumor necrosis factor alpha (TNF-alpha) concentration in the lungs.  Also appears to have other functions important in virulence in models of pneumonia and septicemia.
What are the official names of this protein?
Zinc metalloprotease ZmpB.
What is the protein family that this protein belongs to?
Belongs to the peptidase M26 family.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Multi-pass membrane protein. Secreted, cell wall; Peptidoglycan-anchor.
Protein: RL25_ECO55
Sequence: MFTINAEVRKEQGKGASRRLRAANKFPAIIYGGKEAPLAIELDHDKVMNMQAKAEFYSEVLTIVVDGKEIKVKAQDVQRHPYKPKLQHIDFVRA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: TAGAP_HUMAN
Sequence: MKLRSSHNASKTLNANNMETLIECQSEGDIKEHPLLASCESEDSICQLIEVKKRKKVLSWPFLMRRLSPASDFSGALETDLKASLFDQPLSIICGDSDTLPRPIQDILTILCLKGPSTEGIFRRAANEKARKELKEELNSGDAVDLERLPVHLLAVVFKDFLRSIPRKLLSSDLFEEWMGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIGPNMLTLENDQSLSFEAQKDLNNKVKTLVEFLIDNCFEIFGENIPVHSSITSDDSLEHTDSSDVSTLQNDSAYDSNDPDVESNSSSGISSPSRQPQVPMATAAGLDSAGPQDAREVSPEPIVSTVARLKSSLAQPDRRYSEPSMPSSQECLESRVTNQTLTKSEGDFPVPRVGSRLESEEAEDPFPEEVFPAVQGKTKRPVDLKIKNLAPGSVLPRALVLKAFSSSSLDASSDSSPVASPSSPKRNFFSRHQSFTTKTEKGKPSREIKKHSMSFTFAPHKKVLTKNLSAGSGKSQDFTRDHVPRGVRKESQLAGRIVQENGCETHNQTARGFCLRPHALSVDDVFQGADWERPGSPPSYEEAMQGPAARLVASESQTVGSMTVGSMRARMLEAHCLLPPLPPAHHVEDSRHRGSKEPLPGHGLSPLPERWKQSRTVHASGDSLGHVSGPGRPELLPLRTVSESVQRNKRDCLVRRCSQPVFEADQFQYAKESYI
What is the function of this protein?
May function as a GTPase-activating protein and may play important roles during T-cell activation.
What are the official names of this protein?
T-cell activation Rho GTPase-activating protein, T-cell activation GTPase-activating protein.
Protein: ACCD_CLOK1
Sequence: MLNKFFKKTKYITVSQRALGDIHDDFTKKPSIPNGMWVKCDGCGKVLYKNDMEKNNKVCYHCGYHFRMNALERLELILDKESFYEFDKDITAANPIEFKGYEDKIKNMQNKTNIKEAVITGKGTIGREEAVVCIMDSNFMMGSMGSVVGEKITRAVEKSIELKLPLIIFTTSGGARMQEGIFSLMQMAKVSGAISRLNEEGLLYLSVLTDPTTGGVTASFAMIGDIILAEPGALIGFAGKRVIEQTIKQKLPEGFQKAEFLLQHGFIDNIVSRENLKETLRKILVIHGRGN
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALLA_PSEA7
Sequence: MRTLKIEPLTKEAFAPFGDVIETEGSDYFMINNGSTRRYHKLATVETAQPEDNAIISIFSAEKLEMPLRIRMLERHPLGSQAFIPLLGNPFLVVVAPLGDVPVPGLVRAFLTNGRQGVNYHRGVWHHPVLTIEKRDDFLVVDRSGSGNNCDEHFFTEDEQLLLDPQSNQ
What is the function of this protein?
Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate.  Involved in the utilization of allantoin as nitrogen source.
What are the official names of this protein?
Ureidoglycolate lyase, Ureidoglycolatase.
What is the protein family that this protein belongs to?
Belongs to the ureidoglycolate lyase family.
Protein: Y1738_MYCTU
Sequence: MCGDQSDHVLQHWTVDISIDEHEGLTRAKARLRWREKELVGVGLARLNPADRNVPEIGDELSVARALSDLGKRMLKVSTHDIEAVTHQPARLLY
What are the official names of this protein?
Uncharacterized protein Rv1738.
What is the protein family that this protein belongs to?
To M.tuberculosis Rv2632c.
Protein: MLC1_YEAST
Sequence: MSATRANKDIFTLFDKKGQGAIAKDSLGDYLRAIGYNPTNQLVQDIINADSSLRDASSLTLDQITGLIEVNEKELDATTKAKTEDFVKAFQVFDKESTGKVSVGDLRYMLTGLGEKLTDAEVDELLKGVEVDSNGEIDYKKFIEDVLRQ
What is the function of this protein?
Essential light chain for the class II conventional myosin MYO1.  Acts also as light chain for the class V unconventional myosin MYO2 and for IQG1.  Involved in the assembly of the contractile actomyosin ring at the bud neck during cytokinesis by recruiting IQG1 to the bud neck.  Also required for chitin and MYO2-dependent secretory vesicle deposition to the center of the bud neck for septum formation.  May stabilize MYO2 by binding to its IQ domains.  Its major function is probably not to regulate MYO1 activity, but rather to coordinate actin ring formation and targeted membrane deposition during cytokinesis via its interactions with MYO1, IQG1 and MYO2.
What are the official names of this protein?
Myosin light chain 1, Calmodulin-like myosin light chain MLC1, Myosin-2 light chain.
What are the subcellular locations of this protein?
Bud neck. Bud tip. Note=Concentrates to sites of polarized growth, namely to the incipient bud site in G1, to the bud tip during S and G2 phases of the cell cycle and to the bud neck during cytokinesis.
Protein: YG2A_YEAST
Sequence: MAAGQKKYICSFCLKPFSRSEHKIRHERSHAGVKPFQCQVCKHSFVRRDLLQRHIRTVHRTFLLSSYASMTGDKADIPVSLGVGDVDSTSPRDIKMETLVNSMIKVNSGLINIHYHSSNVEKMDKQQRCVIGKESSSLKKGKSRFKQVKSRLESSISVKILQEYSLDFISSRDILTFFRMGVSHLVENKIFQNFFPDLFSSLQNDELVESFWINKPFGLIIACLGMSISLNQDSQKLWFICCTNLYASSSKHDNDFDTEDILSQTEQHDVFALILFYSLLVMLENNIPVSNSIKKFDVFSMLQDILKPFTVASSSYHYLNSKENAWFIFDLWVNILRDSNNFNNDSLLIFGWFVNQEFISSNPLKDFIYKGPSMSTTDLTLKHINILADSAYVYFIIKKTYPQELPSDFRVHDLLVYLNECFVMQQPIKPETSANPSLFANVMNARITDCKSKSNWLLWETIWFEFINNLTLRNGTTRNIWFIDNFPQVSTSCLLHHSSSFVDETLITTNLSIISMLLNLKSFTLASLNPRNIQLITDIVSFQLKLFSSELIASSDVSPSQVSQLLVNPNVHLMLYFWFDTIYVQRQSYLSSTEKEEFEKVEVFVNDYIITHQKNLVTDLHSILFDFWSDSFIAYHILLHAIVSSLRDNILYPYLIYSPHLNDQTKALLTDISNWSCFALQQPFRKTSRGSLSGASDMKSFSVASCLPLSPNFLKRDSNCNKILLPPLDIKAIEPISTSNYTYVNSAPKQQEKEQPLLRATGNNINLVQTIVVPPQVNMESQEFSASSTDNKQSKNIEIFSQIK
What are the official names of this protein?
Zinc finger protein YGR067C.
What are the subcellular locations of this protein?
Nucleus.
Protein: FLGH1_YERPS
Sequence: MYLRKISAPLMTMLLLNGCAYIPHKPLVDGTTSAQPAPASAPLPNGSIFQTVQPMNYGYQPLFEDRRPRNIGDTLTITLQENVSASKSSSANASRNGTSSFGVTTAPRYLDGLLGNGRADMEITGDNTFGGKGGANANNTFSGTITVTVDQVLANGNLHVVGEKQIAINQGTEFIRFSGVVNPRTISGSNSVTSTQVADARIEYVGNGYINEAQTMGWLQRFFLNVSPY
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein 1, Basal body L-ring protein 1.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: RD21A_ARATH
Sequence: MGFLKPTMAILFLAMVAVSSAVDMSIISYDEKHGVSTTGGRSEAEVMSIYEAWLVKHGKAQSQNSLVEKDRRFEIFKDNLRFVDEHNEKNLSYRLGLTRFADLTNDEYRSKYLGAKMEKKGERRTSLRYEARVGDELPESIDWRKKGAVAEVKDQGGCGSCWAFSTIGAVEGINQIVTGDLITLSEQELVDCDTSYNEGCNGGLMDYAFEFIIKNGGIDTDKDYPYKGVDGTCDQIRKNAKVVTIDSYEDVPTYSEESLKKAVAHQPISIAIEAGGRAFQLYDSGIFDGSCGTQLDHGVVAVGYGTENGKDYWIVRNSWGKSWGESGYLRMARNIASSSGKCGIAIEPSYPIKNGENPPNPGPSPPSPIKPPTQCDSYYTCPESNTCCCLFEYGKYCFAWGCCPLEAATCCDDNYSCCPHEYPVCDLDQGTCLLSKNSPFSVKALKRKPATPFWSQGRKNIA
What is the function of this protein?
Cysteine protease that plays a role in immunity, senescence, and biotic and abiotic stresses (Probable).  Involved in immunity against the necrotrophic fungal pathogen Botrytis cinerea (PubMed:22238602).  Involved in elicitor-stimulated programmed cell death (PCD).  During infection by the necrotrophic fungal pathogen Botrytis cinerea, functions as PCD-promoting protease that is released from the ER body or vacuole to the cytoplasm (PubMed:23398119).  Accumulates in endoplasmic reticulum-derived bodies in epidermal cells and may participate in cell death in stressed or injured cells (PubMed:11577182).  Involved in water stress-induced cell death through its protease activity that is released to the cytoplasm after vacuolar collapse (PubMed:26884487).  Possesses protease activity in vitro and is involved in cell death in the transmitting tract and septum epidermis during flower development (PubMed:26160583).  Possesses peptide ligase activity.  Can ligate peptides to unmodified N-termini of acceptor proteins.  Probably ligates through a thioester intermediate (PubMed:18660805).
What are the official names of this protein?
Cysteine proteinase RD21A, Protein RESPONSIVE TO DEHYDRATION 21, RD21.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Vacuole. Golgi apparatus. Cytoplasm, Stress granule. Cytoplasm, P-body. Note=Specifically accumulates in body structures that directly bud from the endoplasmic reticulum and fuse with the vacuole (PubMed:11577182). Passes through the Golgi on its route to the vacuole (PubMed:22396764).
Protein: PTH_CLOK1
Sequence: MFLIVGLGNIGVKYHRTRHNIGFDFIDLVSKKYNITLNREKFKGNYGEGFIGQNKVILLKPGTYMNLSGESVREAVNFYKIENDRMIIIYDDIDIDIGRFRIRHRGSAGGHNGIKNIILNLGTDVFPRIKIGIGHPNVDLVSYVLGKFSEDDRINIEKVLKTSVEALECIMDFGIEVAMNKFNGFKL
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METAA_CLOK5
Sequence: MPIKIKDDLPAAEILNSENIFIMPENVAFHQDIRPLKIAILNLMPIKITTEVQLLRLIGNTALQIEIELLHLKTHVCKNTSEEYLTNFYRTFDEIKNEKFDGLIITGAPIEQLEFSRVNYWEELKDIMEWSKCHVYSTLHICWGAQAGLYYHYGIPKYILKEKLFGVFKHEVTEEKEKLVRGFDDEFYVPHSRYTEVKREDVEKVKELTILAQSKKAGVYLILDNKGRRIFVTGHSEYDPLTLKDEYMRDISKGEDIKMPENYFPDDNPDRKPVVKWRSHADLLFSNWLNYYVYQETPYDLSEMPPSFL
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLIK_ASPFU
Sequence: MGKAALQDPHGGIWYFAYGSNLRLSVLENRGIKALDIKAVIVPSHYLTFDIFGIPYAEPSFASVAPFAREKKTTLRLGDSPASRDVPPVQGLAYLLNPRDYRQLVISEGGGVAYDEVEVHASILDKDGKPDPGATLIARTLQAKYPWRPNGAPSARYLGLISTGCKQNEPLTAYSDYIDSLPAYEPPTSLHAKVGGLLFLMFWRPPLRLLIRLIRVNTDQDGHCPQWLGWIILTLYGLMWSYHDNIHSKIWGRGDGRKLHFEETPAKEVPVRH
What is the function of this protein?
Gamma-glutamyl cyclotransferase-like protein; part of the gene cluster that mediates the biosynthesis of gliotoxin, a member of the epipolythiodioxopiperazine (ETP) class of toxins characterized by a disulfide bridged cyclic dipeptide (PubMed:15979823, PubMed:21612254).  The first step in gliotoxin biosynthesis is the condensation of serine and phenylalanine to form the cyclo-L-phenylalanyl-L-serine diketopiperazine (DKP) by the NRPS gliP (PubMed:17154540, PubMed:21612254).  GliP is also able to produce the DKP cyclo-L-tryptophanyl-L-serine, suggesting that the substrate specificity of the first adenylation (A) domain in gliP is sufficiently relaxed to accommodate both L-Phe and L-Trp (PubMed:23434416).  The cytochrome P450 monooxygenase gliC has been shown to catalyze the subsequent hydroxylation of the alpha-carbon of L-Phe in cyclo-L-phenylalanyl-L-serine whereas the second cytochrome P450 enzyme, gliF, is presumably involved in the modification of the DKP side chain (PubMed:24039048, PubMed:23434416).  The glutathione S-transferase (GST) gliG then forms a bis-glutathionylated biosynthetic intermediate which is responsible for the sulfurization of gliotoxin (PubMed:21513890, PubMed:21749092).  This bis-glutathionylated intermediate is subsequently processed by the gamma-glutamyl cyclotransferase gliK to remove both gamma-glutamyl moieties (PubMed:22903976, PubMed:24039048).  Subsequent processing via gliI yields a biosynthetic intermediate, which is N-methylated via the N-methyltransferase gliN, before the gliotoxin oxidoreductase gliT-mediated disulfide bridge closure (PubMed:20548963, PubMed:22936680, PubMed:24039048, PubMed:25062268).  GliN-mediated amide methylation confers stability to ETP, damping the spontaneous formation of tri- and tetrasulfides (PubMed:25062268).  Intracellular dithiol gliotoxin oxidized by gliT is subsequently effluxed by gliA (PubMed:26150413).  Gliotoxin contributes to pathogenesis during invasive aspergillosis (PubMed:17601876, PubMed:18199036).  In macrophages and neutrophils, gliotoxin showed inhibition of various different cell functions including cytokine production, antigen presentation, phagocytosis, and production of reactive oxygen species (PubMed:17601876).
What are the official names of this protein?
Gamma-glutamyl cyclotransferase gliK, GGCT gliK, Gliotoxin biosynthesis protein K.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: DEN4C_MOUSE
Sequence: MIEDKGPRVTDYFVVAGLTDTSTLLDQEINRTDTNSIGPKAPITDIAVIIKSAGETVPEGYTCVEATPSALQANLNYGSLKSPELFLCYRRGRDKPPLTDIGVLYEGKERLMPGCEVIQATPYGRCANVNNSSTTSQRIFITYRRAPPVRSQNSLAVTDICVIITSKGETPPHTFCKVDKNLNCGMWGSNVFLCYKKSVPASNAIAYKAGLIFRYPEEDYESFPLSPSVPLFCLPMGATIECWDPQIKYPLPVFSTFVLTGSSAEKVYGAAIQFYEPYSQERLTEKQLTQLGLLTLVEKRVVSKPINSNKCICLLSHWPFFEAFKNFLMFIYKVSVSGPHPLPIEKHISHFMQNIPFPSPQRPRILIQLSVHDAFILSQPVSTPLPLSGANFSSLLMNLGPENCATLLLLVLLESKILLHSLRPAVLTGVAEAVVAMIFPFQWQCPYIPLCPLSLAGVLSAPLPFIVGVDSRYFDLHDPPQDVVCIDLDTNTLYVADERKNINWKQLPKRPCKSLLGTLRRLYQQLCSVHRKPQESSAIEMTPIEADYSWQKKMTQLEMEIQETFLRFMASILKGYRSYLRPITEAPSNKATAADSLFDRQGFLKSRDRAYTKFYTLLSKTQIFIRFIEECSFVSDKDTGLAFFDDCIEKLFPDKGVERTEKVDLDSAEDTRLIELDDSQRSEHTVFIMPPEPPPDDGNNLSPQYSYTYFPRLDLKLFDSPQKLKLCFNRHPPGSSITNSPALMAKRTKQEIKTAHKLAKRCYTNPPQWAKYLFSHCYSLWFICLPAYVRVSHPKVRALQQAHDVLVKMRKTDVDPLDEVCYRVVMQLCGLWVNPVLAVRVLFEMKTARIKPNAITYGYYNKVVLESPWPSSTRSGIFLWTKVRNVVHGLAQFRQPLKKTGQKSQVFSISGGQSDQGYGSKDELVKEGADGHAPEEHTPPELTTTELHIEEECDISAIVSKHLQPTPEPQSPTEPPAWGSSIVKVPSGLFDTNNRTSTGSTSTVLFSTQAPVEDAVFSEVTNFKKNGDRGEKKQKHFPERSCSFSSESRAGMLLKKSSLDLNSSEMAIMMGADAKILTAALTCPKTSPPHVTRTHSFENVNCHLADSRTRMSEGTRDSEHRSSPVLEMLEESQELLEPVVGDNVAETAAEMTCNSLQSNSHSDQSRDTQAGAQDPVNKRSSSYATRKAIEREDVETGLDPLSLLATECVEKTSDSEDKLFSPVISRNLADEIESYMNLKSPLGSKSCSMELHGEGNQEPGSPAVFAHPLERSSSLPSDRGPPARDSTETEKSSPAVSSSKTLTGRFKPQSPYRAYKDRSTSLSALVRSSPNSSLGSVVNSLSGLKLDNILSGPKIDVLKSSMKQAATVASKMWVAVASAYSYSDDEEETNKDYSFPAGLEDHHIVGETLSPNTSVSGLVPSELTQSNTSLGSSSSSGDVGKLQCPAGEVPFSRNIKGQDFEKSDHGSSQNTSMSSIYQNCAMEVLMSSCSQCRACGALVYDEEIMAGWTADDSNLNTTCPFCKSNFLPLLNVEFKDLRGSASFFLKPSTSGDSLQSGSIPSASEPSEHKPTSSSAEPDLISFMDFSKHSETITEEASYTVESSDEIKKTNGDVQSVKMSSVPNSLSKRNVSLTRSHSVGGPLQNIDFSQRPFHGVSTVSLPSSLQEDVDHLGKRPSPPPVSVPYLSPLVLRKELESLLENEGDQVIHTSSFINQHPIIFWNLVWYFRRLDLPSNLPGLILTSEHCNGGVQLPLSSLSQDSKLVYIQLLWDNINLHQEPGEPLYVSWRNLNSEKKPSLLSEQQQAASALVETIRQSIQQNDVLKPINLLSQQMKPGTKRQRSLYREILFLSLVSLGRENIDIEAFDNEYGLAYRSLPSESLERLQRIDAPPSISVEWCRKCFGAPLI
What is the function of this protein?
Guanine nucleotide exchange factor (GEF) activating RAB10.  Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB10 into its active GTP-bound form.  Thereby, stimulates SLC2A4/GLUT4 glucose transporter-enriched vesicles delivery to the plasma membrane in response to insulin.
What are the official names of this protein?
DENN domain-containing protein 4C.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane. Cell membrane. Cytoplasm, cytosol. Note=Associates with SLC2A4/GLUT4 storage vesicles.
Protein: ATAB2_ORYSJ
Sequence: MTTATAIVAGHGLALRRSLHLSKPSCATFSARALPPAAHCCRTVVAAAAPSSRTCRCRSVSSESSTAAAADTADDEEEVTKSDSEEEEMDPLAEVCYLDPEADAEGIREWELDFCSRPILDARGKKVWELVVCDATLSLQFTRFFPNTSINSVTLRDALASVATSLGVPLPDRARFFRSQMQTIISRACNELGVKAVPSRRCVSLLLWLEERYETVYSRHPGFQSGTKPLLTLDNPFPTSLPENLFGDKWAFVQLPFSAVREEVESLERRYAFGAGLDLDLLGFELDENTLIPGVAVESSRAKPLAAWMNGLEICSMEVDTGRANLILSAGVSTRYVYAGYQKSAATTQEAEAWEAAKKACGGLHFLAIQENLNSDGCVGFWLLLDLPPPPV
What is the function of this protein?
Nuclear genome-encoded factor involved in the biogenesis of photosystem I (PSI).  Required for the accumulation of PSI during plant development.  Does not seem to be required for the translation of mRNAs of the PSI subunits.
What are the official names of this protein?
Protein TAB2 homolog, chloroplastic.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: AVT1F_ARATH
Sequence: MDLEEQERDILIQTDDDDCHVDVSYVNDDDDSNASFSLSQNDSAFWPQSYRHSVDLLTGVTPPMVSFIQGRSTETSFSSSIASLYKRRPTSIANSFVSSTSKQPLLSEKDDVSFLSSQVGLSNTDLSYGEPNFCSFPQSVLNGINVLCGISLLTMPYAVKEGGWLGLCILLSFAIITCYTGILLKRCLESSSDLRTYPDIGQAAFGFTGRLIISILLYMELYVCCVEYIIMMSDNLSRVFPNITLNIVGVSLDSPQIFAISATLIVLPTVWLKDLSLLSYLSAGGVFVSILLALCLFWVGSVDGVGFHTGGKALDLANLPVAIGIFGFGFSGHAVLPSIYSSMKEPSKFPLVLLISFGFCVFFYIAVAICGYSMFGEAIQSQFTLNMPQQYTASKIAVWTAVVVPMTKYALALTPIVLGLEELMPPSEKMRSYGVSIFIKTILVLSTLVVALTFPFFAIMGALMGSFLATLVDFIFPCLCYLSILKGRLSKTQIGICVFIIISGIVSGCCGTYSAIGRLVGELNWMVQ
What are the official names of this protein?
Amino acid transporter AVT1F, AtAvt1F.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family. Amino acid/auxin permease (AAAP) (TC 2.A.18.5) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS15_SALSV
Sequence: MSLSTEATAKIVSEFGRDANDTGSTDVQVALLTAQINHLQGHFAEHKKDHHSRRGLLRMVSQRRKLLDYLKRKDVARYTALIERLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: FKBP3_ASHGO
Sequence: MSELLPMATYNLNIEPYSPTPAIDVTVPVTVRLTMAAIDPESLDDEKKPATLRLIRRNPAFDDEDDLLADSEEEEEEESEEESEPETKKPKKKAAKAESEEEDSEEEDSEGEDSDDEFEEFVLATLSPESQYQQTLDLVISPEEEVQFVVTGSYRVSLSGNYVQHPYDDEDSYDEDHEGCGENCACDDDHEGCGDDCACDDDSDYDLTPDEEDILDMEDASDVEAKIEELVEQEEANEKRKADEDEPKAAKKQKKDQKDTKKDAKKDAKKDQKDQKDAKKDAKKEKKVEFKKDLEEGPSKKKDDKPKTKILEGGVVIEDRVVGSGKAAKKGARVGMRYIGKLKNGKVFDKNTSGKPFVFKLGHGEVIKGWDIGVAGMAVGGERRIVIPAAYAYGKQALPGIPANSELTFDVKLVSLK
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
FK506-binding protein 3, Peptidyl-prolyl cis-trans isomerase, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. FKBP3/4 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: F16PA_BURA4
Sequence: MSIARRTTLSKFLIEQQRETNNLPADLRLLIEVVARACKAISYNVSKGALGEALGTAGSENVQGEVQKKLDILSNEILLDANEWGGNLAAMASEEMETFFPIPANYPRGEYLLVFDPLDGSSNIDVNVSIGTIFSVLRCPDGKQATEESFLQPGTEQVAAGYAVYGPQTVFVLTTGNGVNCFTLDREVGSWVLTQSNMQIPADTREYAINASNARHWYEPVQRYVDELNAGKDGPRGDNFNMRWIASMVADVHRILNRGGIFMYPADKRTPDRPGKLRLMYEANPMSFIVEQAGGAATTGTQRIMEVQPTGLHQRVPVFLGSKNEVERVTSYHAEGEGK
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURD_LACLS
Sequence: MKKITKFKDQKILVLGLARSGMAAALVLNELGAIVTVNDGKPFEENKEAQVLLEEGIKVITGSHPIDLLDEDFALMVKNPGIRYDNPMVERAEALKIPVITEVELAYLVSEAPIIGITGTNGKTTTTTLIADILNADGQSAKLSGNIGFPASEVAQKAQATDTLVMELSSFQLMGIDTFRPKIALITNLFSAHLDYHGSQEAYEAAKWRIQENMTADDFLILNFNQEKCRKLADKTKATVLAFSTKEKVSGAYVNEGKIYFKDEFIMEASELSLPGDHNLENALAAIVASKLRGAENEAIIEVLTSFAGVKHRLQYLGEIDGRKVYNDSKATNILATQKALSGFDNSKLWLLAGGLDRGNGFEDLEKDLEDLKGMVVFGQTADKLRLMAEKLNIPVFASQNVATALKEIMPQTQVGDTILLSPACASWDQYKTFEERGDLFIEAFESLK
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GALM_ARTBC
Sequence: MCGVLRQLMLLLLAFLSITPSCSAWNFHHQLNGTTPSNGTTTNGSSSCPLANGASSNPLQVYTIAANNITASFIPYGARLISLMVPDREGKMQDVIVGYDNPQDYVKDTLTNHTYFGCIVGRYANRIRNGTFVLDGTTYNTPKNELNKTQTLHGGSVGYDQRNWTVTALSNSSITFTLFDSGYEHFPGDVINHVTFSVNSSYGLKRPNPQTEFTARTVSLSLTEKTPIMLSPHIYWNLNAFKNETVLEDTLLELPLSSRYVEVDSRLIPTGNIGNVSSSLNGTLDFTKGKLIGKDIKSADGICGANCTGYDNCFIIDRPNNASDWTSSPQTMVPAVNMSSITTGINMLVTTNQQAIQIYSCNGQNGTIPVKGSQVARNKASGDGNGTVVDKIEQYGCLVIETEGWIDGINNPDWGQDPFQIYSPESGPAINWATYVFTAS
What is the function of this protein?
Mutarotase converts alpha-aldose to the beta-anomer.  It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity).
What are the official names of this protein?
Probable aldose 1-epimerase ARB_05372, Galactose mutarotase.
What is the protein family that this protein belongs to?
Belongs to the aldose epimerase family.
What are the subcellular locations of this protein?
Secreted.