PharMolix/UniProtQA huggingface dataset:
Protein: VPR_HV1C4
Sequence: NSATTAVYSFQDWVSA
What is the function of this protein?
Involved in the transport of the viral pre-integration (PIC) complex to the nucleus during the early stages of the infection.  This function is crucial for viral infection of non-dividing macrophages.  May interact with karyopherin alpha/KPNA1 and KPNA2 to increase their affinity for proteins containing basic-type nuclear localization signal, including the viral matrix protein MA, thus facilitating the translocation of the viral genome into the nucleus.  May also act directly at the nuclear pore complex, by binding nucleoporins phenylalanine-glycine (FG)-repeat regions.  Has an anti-apoptotic effect, whereas high level of expression induces apoptosis.  Interacts with mitochondrial permeability transition pore complex (PTPC), presumably through the binding of ANT proteins.  This induces a rapid dissipation of the mitochondrial transmembrane potential, and mitochondrial release of apoptogenic proteins such as cytochrome C or apoptosis inducing factors.  Prevents infected cells from undergoing mitosis and proliferating, by inducing arrest or delay in the G2 phase of the cell cycle.  The arrest in G2 is characterized by low levels of CCNB1-CDC2 complex and corresponding inhibitory phosphorylation of CDC2.  Cell cycle arrest creates a favorable environment for maximizing viral expression and production.  This may be mediated by interacting with and inhibiting human CDC25C, which normally activates the CCNB1-CDC2 complex, or by binding SF3B2/SAP145.  This function is independent of nuclear localization.  Cell cycle arrest reportedly occurs within hours of infection and is not blocked by antiviral agents, suggesting that it is initiated by the Vpr carried into the virion.  Stimulates gene expression driven by the HIV-1 LTR by interacting with human SP1, TFIIB and TFIID.  Moreover, the G2/M cell cycle arrest creates a cellular environment where the HIV-1 LTR is transcriptionally more active.  Essential for unintegrated viral DNA expression.  Detected in the serum and cerebrospinal fluid of AIDS patient, where it may induce cell death to bystander cells.  This necrotic or apoptotic effect might function by entering target cell plasma membrane to form ion channel (By similarity).
What are the official names of this protein?
Protein Vpr, R ORF protein, Viral protein R.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host extracellular space. Note=Incorporation into virion is dependent on p6 GAG sequences. Lacks a canonical nuclear localization signal, thus import into nucleus may function independently of the human importin pathway. Detected in high quantity in the serum and cerebrospinal fluid of AIDS patient (By similarity).
Protein: BIOB_BACCR
Sequence: MKQVQTKRDWKKLAYDVVEEKMITKEDAIAILEADDTEVLEIMNAAYIIRHHHFGKKVKLNMIINTKSGLCPEDCGYCSQSIISEAPIDKYAWLTQEKIVEGAHEAIRRKAGTYCIVASGRRPTDKEVNHVIGAVKEIRETTDLKICCCLGFLNEDQAGRLAEAGVHRYNHNLDTHANNYDSICSTHTYDDRVDTVQKAKQAGISPCSGAIFGMGETIEERAEIAFELQRIDADSIPCNFLVAVKGTPLEGQKELTPVECLKVLAMMRFVNPTKEIRISGGREINLRSVQPIGLFAANSIFVGDYLTTAGQEPTADWGMIADLGFEIEECAL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: RS12_METPP
Sequence: MPTINQLVRHGRQTEVTKSKSPAMQGGPQRRGVCTRVYTTTPKKPNSALRKVAKVRLTNGFEVISYIGGEGHNLQEHSVVLVRGGRVKDLPGVRYHIVRGSLDLQGVKDRKQSRSKYGAKRPKKA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: SYK_LISMF
Sequence: MSNENHEELNDQLIVRREKVDTLREEGIDPFGEKFIRSISPEEIETKFADKSKEELEEAAIEVSVAGRIMTKRVKGKVGFTHIQDRFHQLQIYIRKDAIGEDAYAVFKLADLGDIIGIKGTIFRTNTGELSVKATEFTLLSKSLRPLPDKYHGLKDVEQRYRQRYLDLITNEESQNRFVMRSKILKYTRDYMDNQGFLEVETPVLHTIAGGAAAKPFITHHNALDMELYLRIALELHLKRLIVGGMDKVYEIGRVFRNEGTSTRHNPEFTMLESYAAYEDYEDVMDLVEGLVSTVCKQVNGTTEITYGEYNVDLTPNWRRIHMADAVKEYVGVDFWNVTSDEEARELAKKHNVPVTEHMTYGHILNEFFETYVEEKLIQPTFVYGHPVEISPLAKKNKEDDRFTDRFELFIVGREHANAFSELNDPIDQRERFEAQMKEREQGNDEAHGMDADFLEALEYGLPPTGGLGIGIDRLVMLLTDAPSIRDILLFPTMKHRD
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TA47_TREPA
Sequence: MKVKYALLSAGALQLLVVGCGSSHHETHYGYATLSYADYWAGELGQSRDVLLAGNAEADRAGDLDAGMFDAVSRATHGHGAFRQQFQYAVEVLGEKVLSKQETEDSRGRKKWEYETDPSVTKMVRASASFQDLGEDGEIKFEAVEGAVALADRASSFMVDSEEYKITNVKVHGMKFVPVAVPHELKGIAKEKFHFVEDSRVTENTNGLKTMLTEDSFSARKVSSMESPHDLVVDTVGTGYHSRFGSDAEASVMLKRADGSELSHREFIDYVMNFNTVRYDYYGDDASYTNLMASYGTKHSADSWWKTGRVPRISCGINYGFDRFKGSGPGYYRLTLIANGYRDVVADVRFLPKYEGNIDIGLKGKVLTIGGADAETLMDAAVDVFADGQPKLVSDQAVSLGQNVLSADFTPGTEYTVEVRFKEFGSVRAKVVAQ
What is the function of this protein?
A pathogen-specific membrane antigen (PubMed:2642466, PubMed:1372297).  Most abundant of the membrane lipoproteins, only found in pathogenic treponemes, suggesting that it is an important structural moiety in the cell envelope of virulent treponemal subspecies.  A lipopeptide corresponding to the first 6 mature residues induces host (human and mouse) cytokine release by monocyte cell lines via TLR2 and CD14; nonlipidated protein does not stimulate host cells (PubMed:10426995).  Stimulates host (human) dendritic cell maturation to become MHC class II-positive antigen presenting cells via TLR2, which depends on lipidation; nonlipidated protein does not stimulate maturation (PubMed:11160304).
What are the official names of this protein?
Putative DD-carboxypeptidase TP_0574, 47 kDa lipoprotein, Tp47, Tpp47, 47 kDa membrane antigen, 47-kilodalton major integral membrane immunogen.
What are the subcellular locations of this protein?
Cell inner membrane; Lipid-anchor.
Protein: RL34_META3
Sequence: MPAPRFKSGSFKKISKRGPGNKTLTHHRRSKVSKAKCGACGALLNGVPRGRKIEIAKLSKTEKRPERPYGGFLCPKCLKRLMIEKARNL
What are the official names of this protein?
50S ribosomal protein L34e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL34 family.
Protein: CYOE2_PSEPG
Sequence: MSVKHFIQITKPGIIFGNVLSVAGGFFLASKGHVDFALFLAVVIGTSLVVASGCVFNNCIDRDIDHKMERTKNRVMVQGGMSLPLALIYATLLGVAGFSLLYVQANPLSAFCALIGFIVYVGFYSLWLKRKSVHGTLVGSLSGAMPPVIGYCAVSNSFDLAAVTLLVMFSLWQMPHSFAIAIFRFKDYSAANIPVLPVARGVLAAKKQIVLYVLAFVLATLMLTLGGYAGLGYLAVAAAMGLYWLYMAWGGYKAEDDSKWARKVFGFSILTVTALSVMMGVDSQTAADVLMTYAR
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase 2, Heme B farnesyltransferase 2, Heme O synthase 2.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATP25_PHANO
Sequence: MAKDRDDPAVEDPEFAFLDDSTKSSTNTAHTEEPISVADTELNTSVAEASVETSSAAAPKSSAVDTSIPWYLRQNPAARDAQKPIEIPDLPPNPPPLLKTILEYISITAGLDDLELLDLRHLDPPPALGPKLIMIIATARSEKHLHVAADGFARFLRREHGLKANAAGLLGRNELKIKLRRKAKRMRMLANVGGAVPEGNLDDGIRTGWICCTLSKIEAHPDDMHLPGDNVDEFVGFRSVNPGVNVVVQMFTEEKRVETDLETLWGGVLKTQRREGTVAEEKLKELDEDVEAQESAEVPLISRQEEETETPASPHASVIWNRVAITFLYNDTDTQHSSRTNKALVTLLADFIMSKSADDYHKDFIELSLKKVLMNQRGHTIRRKKDSEEAIRKADLVELAMA
What is the function of this protein?
Probable mitochondrial mRNA stabilization factor.
What are the official names of this protein?
ATPase synthesis protein 25, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ATP25 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: Y595_METST
Sequence: MSDLDEIRRRRMEQLKQQQLAAQQQQGASLEQMQQEEQARQQFENQKKNALRQILTPEARQRLANLRLTKAELVNAIEMQLIQMAQAKRLQIPVTDATLKQILRETTSNKREIHITRK
What are the official names of this protein?
DNA-binding protein Msp_0595.
What is the protein family that this protein belongs to?
Belongs to the PDCD5 family.
Protein: NU3M_REIME
Sequence: MNMFIVLLVNISLASCLILIAFWLPQLNIYTEKANPYECGFDPMSSARLPFSMKFFLVAITFLLFDLEIALLLPLPWAIQMSNIKATMLTSFILVSVLAMGLAYEWLQKGLEWTE
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 3, NADH dehydrogenase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DCX_DICDI
Sequence: MTSTSGKPKMEKFGLQTDKSARVILFRNGDRYHVEGVHCLVHSSKFKTFDQLKLEFSKKVGLFTGNVQKVYSMDKKRIQDIKDFVDGHHYICCGAEPLNTEVIPKGIQDIFGKAEVSDQDDEPKPSKPFVSSVPPPPTPTPTSSSGTTTTSQPTLSASPSVSSAQSPKKPVVSAYKESAVHSIDKFSVQTEKAKVIMCFRNGDRYHSGERVTVHSTKFKTYDQLKEQLSKQVKLPTGPVRKLYLASSGKLVKTMEEIIDGEYYVCAGGETLNPLDFSPTLSEHVKQKKLQEQQQQASEQQKPQEQEIF
What is the function of this protein?
Has a cytoskeleton-independent function in chemotactic signaling during development.
What are the official names of this protein?
Protein doublecortin, DdDCX.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Associated with microtubules and actin.
Protein: RL17_RAT
Sequence: MVRYSLDPENPTKSCKSRGSNLRVHFKNTRETAQAIKGMHIRKATKYLKDVTLKKQCVPFRRYNGGVGRCAQAKQWGWTQGRWPKKSAEFLLHMLKNAESNAELKGLDVDSLVIEHIQVNKAPKMRRRTYRAHGRINPYMSSPCHIEMILTEKEQIVPKPEEEVAQKKKISQKKLKKQKLMARE
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L17, Amino acid starvation-induced protein, ASI, L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CO1A1_ACRSX
Sequence: GGISVPGPMGPSGPRGLPGPPGPGPQGFQGPPGEPGEPGSSGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGPGERGRPGASGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGARGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPSGPPGPKGNSGEPGAPGGEPGPTGIQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGSSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGAPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPTGAPGPIGNLGAPGPKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPVGKEGGKGPRGETGPAGEVGPPGPPGPSGEKGSPGADGPAGAPGTPGPQGISGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGSSGERGPPGPMGPPGLAGPPGESGREGPGAEGSPGRDGSPGPKGDRGEGPPGAPGAPGAPGPVGPAGKSGDRGETGPGPAGPAGPAGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPAGPPGSPGEQGPSGASGPAGPRGPPGSAGSPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPP
What is the function of this protein?
Type I collagen is a member of group I collagen (fibrillar forming collagen).
What are the official names of this protein?
Collagen alpha-1(I) chain, Alpha-1 type I collagen.
What is the protein family that this protein belongs to?
Belongs to the fibrillar collagen family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix.
Protein: THIM_HUMAN
Sequence: MALLRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFKKDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSRITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQSTA
What is the function of this protein?
In the production of energy from fats, this is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA (Probable).  Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain unbranched 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms (Probable).  Also catalyzes the condensation of two acetyl-CoA molecules into acetoacetyl-CoA and could be involved in the production of ketone bodies (Probable).  Also displays hydrolase activity on various fatty acyl-CoAs (PubMed:25478839).  Thereby, could be responsible for the production of acetate in a side reaction to beta-oxidation (Probable).  Abolishes BNIP3-mediated apoptosis and mitochondrial damage (PubMed:18371312).
What are the official names of this protein?
3-ketoacyl-CoA thiolase, mitochondrial, Acetyl-CoA acetyltransferase, Acetyl-CoA acyltransferase, Acyl-CoA hydrolase, mitochondrial, Beta-ketothiolase, Mitochondrial 3-oxoacyl-CoA thiolase, T1.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RISB_CAMHC
Sequence: MNTIEGKLTLTGKEKIAIINARFNHIITDRLVEGAKDAFMRHGGDEKNLSLILVPGAYEIPFALDLAIKSSKFDAICCVGAIIRGSTPHFDYVAAETAKGIAQTTLKYGIPVSFGVLTTENIEQAIERAGSKAGNKGFEAMSSVIEMLNLYKNLKA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: RFAS_ECOLI
Sequence: MTIYFINWVADYELKMIQYLKKKYKIKNITTPKKYNWINKKISKIGMDNAWLGRLFIKHYLNDIKKDDIIIINDSVVNKGINKQILKNINCHKVLLLRNTVGEDFILDNANYFDIIYDFEHRFIGNEKIKAIEQFFPIGMDEIRNYSLSDKNNSQPICFFLGRDKGRLQIINELAERLTTLGCKLDFNVVKDKTSSTTSKYLIEKQISYEENIRRTLNANIIVDITKENQSGWTLRILEALFFNKKLITNNINVFGSEIYSESRFFIIGHDDWDKLEYFINSSVKPMDYDSLYKFSPDKMMSTIVSDFIDK
What are the official names of this protein?
Lipopolysaccharide core biosynthesis protein RfaS.
Protein: HBE_CALGO
Sequence: MVHFTAEEKAAITSLWGKMNVEEAGGEALGRLLVVYPWTQRFFDNFGNLSSPSAILGNPKVKAHGKKVLTSFGDAIKNMDNLKTTFAKLSELHCDKLHVDPENFRLLGNVMVIILATHFGKEFTPEVQAAWQKLVSAVAIALGHKYH
What is the function of this protein?
The epsilon chain is a beta-type chain of early mammalian embryonic hemoglobin.
What are the official names of this protein?
Hemoglobin subunit epsilon, Epsilon-globin, Hemoglobin epsilon chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: CH10_SHEDO
Sequence: MNIRPLHDRVIVKRLEVESKSAGGIVLTGSAAEKSTRGEILAVGNGRLLENGTVKPLDVKVGDVVIFNEGYGVKKEKIDGEEVLILSEADLMAVVG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BTBD9_BOVIN
Sequence: MSNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQYFRALLYGGMRESQPEAEIPLEDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLSLSKTALLNIVLRDSFAAPEKDIFLALLNWCKHNSNENHAEIMQAVRLPLMSLTELLNVVRPSGLLSPDAILDAIKVRSESRDMDLNYRGMLIPEENIATMKYGAQVVKGELKSALLDGDTQNYDLDHGFSRHPIDDDCRSGIEIKLGQPSIINHIRILLWDRDSRSYSYFIEVSMDELDWIRVIDHSQYLCRSWQKLYFPARVCRYIRIVGTHNTVNKIFHIVAFECMFTNKTFTLEKGLIVPMENVATIADCASVIEGVSRSRNALLNGDTKNYDWDSSYTCHQLGSGAIVVQLAQPYMIGSIRLLLWDCDDRSYSYYVEVSTNQQQWTMVADRTKVSCKSWQSVTFERRPASFIRIVGTHNTANEVFHCVHFECPEQQSAQKDSSDEPGTGGASAAGQQLDPHALQAPSGSSLPSSPGSNSRSPNRQHQ
What are the official names of this protein?
BTB/POZ domain-containing protein 9.
Protein: RL11_SACEN
Sequence: MPPKKKKLAAIIKLQISAGQANPAPPVGPALGQHGVNIMEFCKAYNAATESQRGDVVPVEISVFEDRSFDFKLKTPPAAKLLLKAAGVQKGSGEPHKTKVGKVSMDQIREIAQTKMVDLNANDLDQASKIIAGTARSMGLTVEG
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: EFP_BACC7
Sequence: MISVNDFRTGLTIAVDNGLWQVLDFQHVKPGKGAAFVRSKLRNLRTGSVQEKTFRAGEKVEKAHIENRRMQYLYASGESHVFMDNGTYEQIELGEKQIERELKFLKENMEVSIMTYQGEVLGVELPNTVELQVTETEPGIKGDTASNVTKPATLETGLVVQVPIFINEGETLIINTGEGKYVSRA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XERD_PASMU
Sequence: MKDSALIELFLNEIWIEKQLSQNTIASYRLDLTALIQWLEKQQLTLINLDAIDLQTFLGERLNQGYKATSTARLLSAMRKLFQYLYREKYRTDDPSAVLSSPKLPSRLPKYLTEQQVTDLLNSPDVDIPLELRDKAMMELLYATGLRVTELVSLTIENININQGIVRVVGKGNKERIVPIGEEATYWIRQFMLYGRPFLLHGQSSDVVFPSKRALQMTRQTFWHRIKHYALLSDIDINSLSPHVLRHAFATHLVNHGADLRVVQMLLGHSDLSTTQIYTHVAKERLKHLHERYHPRG
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerD.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPSA2_ARATH
Sequence: MVGNDWVNSYLEAILAAEPGIANSKPPGTGDSKSSLLLRERGHFSPTRYFVEEVITGFDETDLHRSWVQAAATRSPQERNTRLENLCWRIWNLARQKKQVEGKNAKREAKREREREKARREVTAEMSEDFSEGEKADLPGEIPTPSDNNTKGRMSRISSVDVFENWFAQHKEKKLYIVLISLHGLIRGENMELGRDSDTGGQVKYVVELARALGSMPGVYRVDLLTRQVTAPDVDSSYSEPSEMLNPIDTDIEQENGESSGAYIIRIPFGPKDKYVPKELLWPHIPEFVDRALSHIMQISKVLGEQIGGGQQVWPVSIHGHYADAGDSTALLSGALNVPMVFTGHSLGRDKLEQLLKQGRPKEEINSNYKIWRRIEAEELCLDASEIVITSTRQEVDEQWRLYDGFDPVLERKLRARMKRGVSCLGRFMPRMVVIPPGMEFHHIVPHDVDADGDDENPQTADPPIWSEIMRFFSNPRKPMILALARPDPKKNLVTLVKAFGECRPLRELANLTLIMGNRNDIDELSSTNSSVLLSILKLIDKYDLYGQVAMPKHHQQSDVPEIYRLAAKTKGVFINPAFIEPFGLTLIEAGAHGLPTVATINGGPVDIHRVLDNGLLVDPHDQQAIADALLKLVSDRQLWGRCRQNGLNNIHLFSWPEHCKTYLARIASCKQRHPKWQRVEFENSDSDSPSDSLRDINDISLNLKLSLDGEKSGSNNGVDTNLDAEDRAAERKAEVEKAVSTLAQKSKPTEKFDSKMPTLKRRKNIFVISVDCSATSDLLAVVKTVIDAAGRGSSTGFILSTSMTISETHTALLSGGLKPQDFDAVICSSGSELYFTSSGSEDKTALPYTLDADYHSHIEFRWGGESLRKTLIRWISSVEEKKKTKKGEILVEDESSSTNYCLSFKVKDPALMPPMKELRKLMRNQALRCNAVYCQNGARLNVIPVLASRSQALRYLLVRWGIDLSNMVVFVGDSGDTDYEGLLGGIHKTVILKGLASDLREQPGNRSYPMEDVTPLNSPNITEAKECGRDAIKVALEKLGISLLKP
What is the function of this protein?
Plays a role in photosynthetic sucrose synthesis by catalyzing the rate-limiting step of sucrose biosynthesis from UDP-glucose and fructose- 6-phosphate.  Involved in the regulation of carbon partitioning in the leaves of plants.  May regulate the synthesis of sucrose and therefore play a major role as a limiting factor in the export of photoassimilates out of the leaf.  Plays a role for sucrose availability that is essential for plant growth and fiber elongation.  Required for nectar secretion.
What are the official names of this protein?
Probable sucrose-phosphate synthase 2, Protein KAONASHI 2, Sucrose-phosphate synthase 2F, AtSPS2F, Sucrose-phosphate synthase 5.2, AtSPS5.2, UDP-glucose-fructose-phosphate glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family.
Protein: NADE_MACFA
Sequence: MGRKVTVATCALNQWALDFEGNLQRILKSIEIAKNRGARYRLGPELEICGYGCWDHYYESDTLLHSFQVLAALLESPVTQDIICDVGMPVMHRNVRYNCRVIFLSRKILLIRPKMALANEGNYRELRWFTPWSRSRHTEEYLLPRMIQDLTKQETAPFGDAVLATWDTCIGSEICEELWTPHSPHIDMGLDGVEIITNASGSHHVLRKANTRVDLVTMATSKNGGIYLLANQKGCDGDRLYYDGCAMIAMNGSVFAQGSQFSLDDVEVLTATLDLEDVRSYRAEISSRNLAASRASPYPRVKVDFALSCHEDLLAPVSEPIEWKYHSPEEEISLGPACWLWDFLRRSQQGGFLLPLSGGVDSAATACLVYSMCCQVCKSVRSGNQEVLADVRTIVNQISYTPQDPRDLCGHILTTCYMASKNSSQETCTRARELAQQIGSHHISLNIDPAVKAVTGIFSLVTGKSPLFAAHGGSSRENLALQNVQARIRMVLAYLFAQLSLWSRGIRGGLLVLGSANVDESLLGYLTKYDCSSADINPIGGISKTDLRAFVQFCIERFQLTALQSIISAPVTAELEPLADGQVSQTDEEDMGMTYAELSVYGKLRKVAKMGPYSMFCKLLGMWRHVCTPRQVADKVKWFFTKHSMNRHKMTTLTPAYHAENYSPEDNRFDLRPFLYNTSWPWQFRCIENQVLQLERAAPQSLDGVD
What is the function of this protein?
Catalyzes the final step of the nicotinamide adenine dinucleotide (NAD) de novo synthesis pathway, the ATP-dependent amidation of deamido-NAD using L-glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine-dependent NAD(+) synthetase, NAD(+) synthase [glutamine-hydrolyzing], NAD(+) synthetase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAD synthetase family.
Protein: RL36_AGRRK
Sequence: MKIKNSLKSLKARHRDNRLVRRKGRMYIINKLNPRFKARQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: OM29_ACIBA
Sequence: DEAVVHDSYAFDKNQLIPVGARAE
What is the function of this protein?
May be involved in transporting molecules across the outer membrane.
What are the official names of this protein?
29 kDa outer membrane protein, 29 kDa OMP.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: TILS_LEPIN
Sequence: MRDKISESTQKIFHAVWERIAPFHEMIQSRPAVLSYSGGKDSSILLHFYFWLWIEKKIPAPCIYHLDHSIRFNLEQEKKIFEYADSTFPFSKIFKKKNIPALSRRLGKTLEETGRAFRYKDLKKISDQYEGYIVTGHHSSDYLETILLNLIRGGGWNSLRTLGWYEKNRFRPLFAFSQDEIETILQSEFWKIFEDESNNSDEYLRNRIRSYIIPLLLREGANPDRIYKNFHRIEKPVSKIFSKKNSDHKIPSFLKIDIWVLNDLSQRERKFFIDRYLRSLNLYPTTRNFFRDLTDLLQKENSFSLENKETWFWKSTSSDLYLIPKNSPCLREFRFEPKEMVLKWNGNQKKIPPDLIPDLCPAGAKIRKNGMSIEISEILRQKEIPVPVRKMLPILRGERKVDVICLSLWDPKIGDIVADREVEILPDFQEPGV
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.