PharMolix/UniProtQA huggingface dataset:
Protein: TEG7_HHV2H
Sequence: MASLLGVLCGWGTRPEEQQYEMIRAAAPPSEAEPRLQEALAVVNALLPAPITLDDALESLDDTRRLVKARALARTYHACMVNLERLARHHPGLEGSTIDGAVAAHRDKMRRLADTCMATILQMYMSVGAADKSADVLVSQAIRSMAESDVVMEDVAIAERALGLSTSALAGGTRTAGLGATEAPPGPTRAQAPEVASVPVTHAGDRSPVRPGPVPPADPTPDPRHRTSAPKRQASSTEAPLLLA
What is the function of this protein?
Plays several roles during the time course of infection, including egress of virus particles from the perinuclear space and secondary envelopment of cytoplasmic capsids that bud into specific trans-Golgi network (TGN)-derived membranes.
What are the official names of this protein?
Tegument protein UL51.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae UL51 family.
What are the subcellular locations of this protein?
Virion tegument. Host cytoplasm. Host Golgi apparatus.
Protein: KATG_AERS4
Sequence: MSNNSERSQGKCPVMHGGTTSGEQANMAWWPKSLNLDMAALKQDVTALMTDSQDWWPADWGHYGALMIRMAWHSAGTYRIADGRGGGSTGNQRFAPLNSWPDNANLDKARRLLWPIKKKYGNKISWADLIILAGTVAYESMGLKTFGFAFGREDIWHPEKDIYWGAEKEWLAPSSKPGGRYSGERDLDNPLAAVMMGLIYVNPEGVDGNPDPLKTAKDMRVTFARMAMDDEETVALTAGGHTVGKCHGNGDARLLGPEPEGAAVEDQGLGWLNKTQRGIGRNAVTSGIEGAWTTHPTRWDNGYFYLLFNYEWELKKSPAGAWQWEPVNIREEDKPVDVEDPAIRHNPIMTDADMALKFDPEYRKIAERFRADPAAFSDAFARAWFKLTHRDLGPKTRYVGPYVPAEDLIWQDPVPAGRTDYDVAAVKASIAASGLSISDMVSTAWDSARTFRGSDLRGGANGARIRLAPQNEWEGNEPARLARVLKVLEPIAAASQISVADVIVLAGNLGVELAARAAGVEVTVPFSPGRGDASQARTDVASFDVLEPLADGYRNWLKKDYAVTAEELMLDRTQLMGLTAHEMTVLVGGMRVLGTNHGGTRHGVFTEREGALTNDYFVNLTDMANTWHPSGDRLYEVRDRKSGKVKWTATRIDLVFGSNSVLRAYAEVYAQDDNKEKFVCDFISAWNKVMNADRFDLMS
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: ATPE_SACD2
Sequence: MAMTVHCDIVSAEQEIFSGAIELLVAASVEGDVGINYGHAPLLTALKPGPVRVKKLDGEEEIFYVSGGYLEVQPHVVTVLADTALRAGDMDEAAAEAAMKEAEQAIQSSEGLDYSKAAAQLAESAAQLRTLQAIRKKLQR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: URE1_FRAAA
Sequence: MSRLDRSRYASLYGPTVGDRIRLADTDLFIEVTEDRSRGPGLAGSGDEAVFGGGKVIRESMGQSRATRAQGAPDLVITGAVVLDHWGVIKADVGIRDGRIVALGKAGNPDTMDGVHPDLVIGPGTEIIAGNGKILTAGAVDCHVHLICPQQVPEALGAGITTLIGGGTGPAEGTKATTVTPGSWNLARMLSAMDDWPVNIVLLGKGNTVNDESMWEQLRAGAAGFKLHEDWGTTPAAIDACLRVADAAGVQVALHSDTLNEAGFVEDTLAAIAGRAIHAYHTEGAGGGHAPDIITVAAAANVLPSSTNPTRPHTVNTLDEHLDMLMVCHHLNPSVPEDLAFAESRIRPSTIAAEDILHDLGAISMIGSDSQAMGRIGEVVLRTWQTAHVMKRRRGALPGDGPADNARARRYVAKYTICPAVAHGLDAQIGSVEPGKLADLVVYDPAFFGVRPSLVLKGGFVAWAAMGDANASIPTPQPVLPRPMWGAARGPAAASSLTFVSPAAISDGLPERLGLATPVVPVEDVRRRGKADLPENTATPDIRVDPDTFTVSIDGEAVEADPVRELPMAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FERN_SOLLC
Sequence: MLMKRLFSSSHVFSSSSASSNLLKIGSVLKQARTFADDDVLGYSKLTHDANPLHFDAECAKNAGFTDCLVPGMLVASLFPRIIAAHFPGAIYVSQTLHFKLPVYIGDEIIAEVQAVSIRQIKNKYIAKLSTKCIKRDGPLVIDGEATAMLPSLVMEPPNLEITSS
What is the function of this protein?
3-hydroxyl-[acyl-carrier-protein] (3-hydroxyl-ACP) dehydratase required for mitochondrial fatty acid synthesis (mtFAS) (PubMed:35640121).  Essential for photorespiration, tomato morphogenesis and plant development, probably by influencing mitochondrial membrane lipid composition and other lipid metabolic pathways, and by contributing to energy supply and reactive oxygen species (ROS) homeostasis (PubMed:35640121).
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FERN, mitochondrial, 3-hydroxyl-ACP dehydratase FERN, Protein FERN-LIKE, SlFERN.
Protein: LOLB_AZOSB
Sequence: MRPARRFLAALACVAGALLSACATPTPRAERAVLREVSAQFFLGGRMSASDGNQGASGRIEWQHDTAGDEVTVYSPLGQIAARLISSPTGAELLTSDGQRYQAENAEALMPRVFGFGVPVSRLAHWVQAAPPPGAEVRELDAAGRPALVIDQGWRVDYLEYPDTRARTLPTRVEVSRGDARIRLIIDQWELLQ
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: RL29_YERP3
Sequence: MKAQELREKSVEELNTELLNLLREQFNLRMQAASGQLQQTHLLKQVRRNVARVKTLLTEKAGA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: PGK_NOSP7
Sequence: MSKKSLASLSSADISGKRALVRVDFNVPVDDQGKITDDTRIRAALPTIQDLTQKGAKVILASHFGRPKGVDDKLRLTPVAKRLSELLGQEVIKTDDSIGDEVAAKVAALQNGQVLLLENVRFYPEEEKNDAEFAKKLAANADFYVNDAFGTAHRAHASTEGVTKFLSPSVAGYLVEKELQYLQNAIENPQRPLAAIIGGSKVSSKIGVIETLLEKCDKLIIGGGMIFTFYKARGLSVGKSLVEEDKLELAKSLEAKAKERGVALLLPTDVVLADNFAPDANSQTVSIENIPDGWMGLDIGPDSVKFFQEALADTKTVIWNGPMGVFEFDKFAAGTEAIAHTLAEIGKTGTTTIIGGGDSVAAVEKVGLADQMSHISTGGGASLELLEGKVLPGIAALDDA
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIG_PHLRA
Sequence: MAFKQLLSAVTLALAASAASVTRRATCPDGTQLMNAECCALLAVRDDLQNNMFNNECGDEAHEALRLTFHDAIAISPAMEATGQFGGGGADGSIMIFSDIETKFHPNIGLDEVVESFRPFQQRSGMGVADFIQFSGAVGTSNCPGAPTLNAFIGRKDATQAAPDGLVPEPFHDVNTILARFNDAGDFDELETVWFLIAHSVAAQNDIDPAVSHAPFDSTPSVMDGQFFIETQLRGVEFIGSGGIEGVAESPVKGEFRLMSDQQIARDNRTACEWQSFGTDQAKLQNRFQFIFEAMGQLGTDPTTLIDCSDVLPVPPPLSTVPHFPAGITINDVEPACAETPFPTLPTDPGPATAVAAVPRD
What is the function of this protein?
Depolymerization of lignin.  Catalyzes the C(alpha)-C(beta) cleavage of the propyl side chains of lignin.
What are the official names of this protein?
Ligninase-3, Diarylpropane peroxidase, Lignin peroxidase, Ligninase III.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Ligninase subfamily.
Protein: CD109_MOUSE
Sequence: MRSRRLLSAAHLLCLCAVALAAPGSRFLVTAPGIIRPGANVTIGVDLLENSPPQVLVKAQVFKIASNKSRSILEAEGVFHRGHFKTLVLPALPLSSADKIYELHINGQSENEIVFSNRTRLTFESKSISVLIQTDKAFYKPKQEVKFRVLTLCSDLKPYRTSVDIFIKDPKSNVIQQWFSQKGDLGVVSKTFQLSSNPIFGDWSIQVQVNDQQYYQSFQVLEYVLPKFEVTVQTPLYCSLKSKQLNGSVIAKYTYGKPVKGSLSLTFLPLSFWGKKKNITKSFEINGFANFSFDNYEMKKVMNLKPLTDVSEGSYENVDPSFPGPAEIIATVTESLTGISRMASTNVFFKQHDYIIEIFDYTTVLKPSLNFTATVKVSRSDGNQLTPEEIENDLVTVVTQRKNNHPESQRDQEMDYIQTVNYTIPQNGIIKIEFPVMSISGELQLKAYFLDGTSSVTVHSMFTSPSKTYIQLKTRDEYIKVGSPFDLMVSGNRQFKDLSYMVISKGQLVAAGKQSSRTFSLTPEASWAPKACIIAYYIAEDGEIINDILKIPVQLVFENKVKLFWSKPTVKPSDKVSLRISATQSDSLVGIVAVDKSVTLMENSNSITMETMVHELELYNTEYYLGMFMNSFAVFQECGLWVLTDATLIRDSIDEVYDTEEYSERFAEENEANLVDFEDASSVNNVHVRKNFPETWIWLDAYMGSKIYEEFEVTVPDSITSWVASAFVISEDLGFGLTTVPAELQAFQPFFLFLNLPYSVIRGEEFALEVSIVNYLKDTIKVVILIEESDSFDILMTSNDTNGTIYRKTVQVPRDNGVTLVFPIKPTHLGEIPITVTAASPTASDAVTQTIVVKPEGIEKSYSKSVLLDLTDSNVESKQQSMRFSFPPDTVIGSERVQITAIGDILGSSINGLSSLIRMPYGCGEQNMIYFAPNIYILDYLTKQKQLTVNLKEKALSYMRQGYQRELLYQREDGSFSAFGDIDSSGSTWLSAFVLRCFLEADYYIDIDQDVLHRTYTWLNAHKKFNGEFWEPGRVIHSELQGGTKSPVTLTAYIVTSVLGYKKYQPNIDVQDSIKFLEFEFSRGISDNYTLAIISYALSTVGSPKAEEALNLLMQRSEKEGDTQFWLSSGPALSGSWQPRSVDIEIAAYALLAHTLHHVSEGIPVMRWLIQQRNSLGGFVSTQDTVVALKALSEFSALVHKENTDIQLTVTGPGIPRSIHFRIDSQNLFLLHQEELHALDPITVNVSAHGSGFAICQLNVDYNVKGSGSSKRRRSTENQEVFDLDVIVNNEDDISHLNLNVCTSHLGSERTGMVLMEVNLLSGFSASSDSIPLSETLKKVEYDNGKLNLYLDSVNESQFCVNIPTVRDYKVSNIRDGSVSVMDYYEPRRQAVRSYNTQVKLSSCYLSPDTNCKSHTDGATDSLRRSSSLLVFCSVLLYFVQH
What is the function of this protein?
Modulates negatively TGFB1 signaling in keratinocytes.
What are the official names of this protein?
CD109 antigen, GPI-anchored alpha-2 macroglobulin-related protein.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: MBOA1_ARATH
Sequence: MDMSSMAGSIGVSVAVLRFLLCFVATIPVSFACRIVPSRLGKHLYAAASGAFLSYLSFGFSSNLHFLVPMTIGYASMAIYRPKCGIITFFLGFAYLIGCHVFYMSGDAWKEGGIDSTGALMVLTLKVISCSMNYNDGMLKEEGLREAQKKNRLIQMPSLIEYFGYCLCCGSHFAGPVYEMKDYLEWTEGKGIWDTTEKRKKPSPYGATIRAILQAAICMALYLYLVPQYPLTRFTEPVYQEWGFLRKFSYQYMAGFTARWKYYFIWSISEASIIISGLGFSGWTDDASPKPKWDRAKNVDILGVELAKSAVQIPLVWNIQVSTWLRHYVYERLVQNGKKAGFFQLLATQTVSAVWHGLYPGYMMFFVQSALMIAGSRVIYRWQQAISPKMAMLRNIMVFINFLYTVLVLNYSAVGFMVLSLHETLTAYGSVYYIGTIIPVGLILLSYVVPAKPSRPKPRKEE
What is the function of this protein?
Lysophospholipid acyltransferase with broad specificity (PubMed:18154737).  Mediates the conversion of lysophosphatidylethanolamine (1-acyl-sn-glycero-3-phosphoethanolamine or LPE) into phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine or PE) (LPEAT activity) (PubMed:18154737).  Catalyzes the acylation of lysophosphatidylserine (1-acyl-2-hydroxy-sn-glycero-3-phospho-L-serine or LPS) into phosphatidylserine (1,2-diacyl-sn-glycero-3-phospho-L-serine or PS) (LPSAT activity) (PubMed:18154737).  Can convert lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC) (LPCAT activity) (PubMed:18154737, PubMed:24189065, PubMed:25268378).  Exhibits preference for C18-unsaturated acyl-CoA when transferring an acyl group to lysophosphatidylcholine (PubMed:24189065, PubMed:25268378).  Can also utilize lysophosphatidylglycerol (LPG) as substrate in vitro (PubMed:18154737).  Has neither activity towards lysophosphatidic acid (LPA) nor lysophosphatidylinositol (LPI) (PubMed:18154737).  Lysophospholipid acyltransferases catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle (Probable).  The primary function of the Lands cycle is to provide a route for acyl remodeling to modify fatty acid (FA) composition of phospholipids derived from the Kennedy pathway (PubMed:23150634, PubMed:22932756).  Is involved in PC acyl editing and phosphocholine headgroup exchange between PC and diacylglycerols.  This processes control the majority of acyl fluxes through PC to provide polyunsaturated fatty acids for triacylglycerols synthesis in seeds (PubMed:22932756, PubMed:24189065).  Involved with LPCAT2 in the direct incorporation of newly synthesized fatty acids exported form the chloroplast into PC through acyl editing (PubMed:31511316).
What are the official names of this protein?
Lysophospholipid acyltransferase 1, AtLPLAT1, 1-acylglycerophosphocholine O-acyltransferase, 1-acylglycerophosphoethanolamine O-acyltransferase, 1-acylglycerophosphoserine O-acyltransferase, Lysophosphatidylcholine acyltransferase 1, LPCAT1, Lysophosphatidylethanolamine acyltransferase, LPEAT, Lysophosphatidylglycerol acyltransferase, LPGAT, Lysophosphatidylserine acyltransferase, LPSAT.
What is the protein family that this protein belongs to?
Belongs to the membrane-bound acyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: EI2BG_BOVIN
Sequence: MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVITTKDVQKALCADFNKMKMKLDIVCIPDEADMGTADSLRHIYQKLKTDVLVLSCDLITDVALHEVVDLFRAHDASLAMLMRKGQESLEPVPGQKGKKKAVEQRDFVGVDSTGKRLLFMANEADLDEELIIKGSILQKHPRIRFHTGLVDAHLYCLKKYVVDFLMENKSITSIRSELIPYLVRKQFSSASSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLTLAPYDTCWNACRGDSWEGLSRSQVRCYVHIMKEGLCSRVSTLGLYMEANRQVSKLLPVICPEESLIHSSAQIVSKHMVGADSLIGPDTQVGEKSSIKHSVIGSSCVIRDRVTVTNCLLMNSVTVEEGSNIQSSIICNDAVIEKGADIKNCLIGSGQRIEAKAKRVNVIVGNDQFLEI
What is the function of this protein?
Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
What are the official names of this protein?
Translation initiation factor eIF-2B subunit gamma, eIF-2B GDP-GTP exchange factor subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B gamma/epsilon subunits family.
Protein: THIOT_DROME
Sequence: MVYPVRNKDDLDQQLILAEDKLVVIDFYADWCGPCKIIAPKLDELAHEYSDRVVVLKVNVDENEDITVEYNVNSMPTFVFIKGGNVLELFVGCNSDKLAKLMEKHAGVYTDEAADVKAVHIDGECIVDLTAESSESDNDNNNVNEVSAHDENAVLEH
What is the function of this protein?
Probably participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.  Its tissue specificity suggests a regulatory role in the germline.
What are the official names of this protein?
Thioredoxin-T, ThioredoxinT.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Specifically associated with the Y chromosome loops.
Protein: TRMB_BOMMO
Sequence: MALPQKKYYRQRAHSNPIADHCFDYPSHPDDYDWTPLYPIISEKPNQVEFLDVGCGYGGLLVALSPMFPSNLMLGSEIRVKVSDYVNDRIKALRVQYPDQYQNVAVLRTNAMKYLPNFFHKGQLKKMFFLYPDPHFKKAKHKWRIINKWLLSEYAYVLCEQGIVYTITDVKDLNEWMVAHFEEHPLFESVPEEELKEDPIIEKLYESTEEGQKVTRNNGEKFLAVFRRIADKTKTN
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CCD78_XENLA
Sequence: MDSTEDRETPLKDQIRRLTNENVQLQDRNERLYAKLGELQDKMGKLAGSKTDLSSKLVLSEEEKLKISKELIELQIETNKIREHYEAETFELKNTILTLENRLMSLELQKEKLAGEHESVKERLQAVDANRKELADEYIVLKSNYLALSKEHEKEVAKNDELSMELLNLASRRGQDETYSQSRALVNEATAELDRVKAMVNRLSARNIKPEDLVATEYERQKLERNLLGNQDHIREEIENMKKIHETQQQRLEERIIAMGKELQEAKRAIRNTQHKMAEQSAVLLTSQSQLQETEAQNSHLQLQLKELNEEYRSRLNRYIQDLADYVDGTARSKGDGTRMKHFVDNMLSDIKASHRSREEQLAGAARQYKKRMQNLIKKHQSLLIAYRMQREQLLASGNQDVEPGPPEHHFTITDPELQSQVGLELNRLREDKARLETQIHDLKEKKRLSDAGTSNQHVEHGGKLQEESWAEIRKQLREFTHNTQEELERERSQLLSRALVAEEQVAELQDYVDKHLARYKQEILRLRKLLGNEEQRAVSADAPQSLLIRALRRNSHEM
What is the function of this protein?
Component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells that can generate more than 100 centrioles.  Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells (G1/0) and not in S phase.  Essential for centriole amplification and is required for cep152 localization to the deuterosome.
What are the official names of this protein?
Coiled-coil domain-containing protein 78, xCCDC78.
What is the protein family that this protein belongs to?
Belongs to the CCDC78 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localizes to centrioles and deuterosome.
Protein: HXCBA_TAKRU
Sequence: MFNSVNLGNFCSQTRKDRTSEFGDRTGCASNIYLPSCTYYVPEFSAVSSFLPQATSRQISYPYSTNLSQVQPVRDVSYGLDPASKWHRSNYASCYSGEDLVHRDCLPPSTMTEMLMKNESVYSHHHHHHTHPGSNHPSAGFYSGVGKNNVLPQGFDRFFETAYCSSTDNQSDICLQKGEGGKQESDSQQPQQPQQQRQQPSAALAGASEQEKDPGDEEEQTNSGSCSTSSPAATKEGNAGKSSHSSTPRTRKKRCPYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLSRDRLQYFSGNPLL
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-C11a.
What is the protein family that this protein belongs to?
Belongs to the Abd-B homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ROT1_ASPOR
Sequence: MLARYFSLSLLATAVSAASISDLVGTWSTKSRKVVTGPDFYDPINDKFLEPNLTGISYSFTEDGHYEEAYYRAVANPVNPSCPKGIMQWQHGKFVLNSDGSLELTPIASDGRQLVSDPCSSSLATYTRYNQTETFNVSKDPYHGIQRLDLKRFDDSPMHPMYLVYQPPQMLPTTTLNPVSETGKSKRHVARDTDRLPGVRNLITKEELTNPDRWLWVGVFATALGGITLFYS
What is the function of this protein?
Required for normal levels of the cell wall 1,6-beta-glucan.  Involved in a protein folding machinery chaperoning proteins acting in various physiological processes including cell wall synthesis and lysis of autophagic bodies (By similarity).
What are the official names of this protein?
Protein rot1.
What is the protein family that this protein belongs to?
Belongs to the ROT1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: G3P_SULIM
Sequence: MISVAVNGYGTIGKRVADAILKQPDMRLIGVAKTSPNYEAFIAHRKGIKIYVPQQSIKKFEESGIPVAGTIEDLVKASDIVVDTTPNGVGAQYKPIYQQFQRNAIFQGGEKAEVADISFSALCNYDEALGKKYIRVVSCNTTALLRTICTINKVTKVEKVRATIVRRAADQKEVKKGPINSLVPDPATVPSHHAKDVNSVIKNLDIVTMAVIAPTTLMHMHFINITLKDKVEKKDVLSVLENTPRIVLISSKYDAEATAELVEVARDLKRERNDIPEVMVFDDSVYVKDNEVMLMYAVHQESIVVPENVDAIRASTRLMSAEDSIRITNESLGILKGYLI
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURD_CAMJE
Sequence: MKISLFGYGKTTRAIAENLVDKFGPFDIYDDHFTETKKDTLGNLLLNPNDFDDNLSDIEIPSPGFPPKHKLIQKAKNLQSEYDFFYDIMPKSVWISGTNGKTTTTQMATHLLSHIGAVMGGNVGTPLAELNPYAKLWILETSSFTLHYTHKAKPEIYALLPISPDHLSWHGSFDNYVQDKLSVLKRMNECDVVILPKIYANTPTKAHKISYEDEKDLAVKFGIDTEKISFKSPFLLDAIMALAIEKILLDTLSYKLLNSFVMEKNKLEELKDSQNRLWVNDTKATNESAVMAALSRYKDKKIHLIIGGDDKGVDLSNLFDFMKGFDIELYAIGISTEKMLDYAKKANLKAYKCEVLSKAVNEISNHLRVNEVALLSPACASLDQFNSYAERGKVFKECVNKI
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_ECOL6
Sequence: MHCPFCFAVDTKVIDSRLVGEGSSVRRRRQCLVCNERFTTFEVAELVMPRVVKSNDVREPFNEEKLRSGMLRALEKRPVSSDDVEMAINHIKSQLRATGEREVPSKMIGNLVMEQLKKLDKVAYIRFASVYRSFEDIKEFGEEIARLED
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: GUAC_CITK8
Sequence: MRIEEDLKLGFKDVLIRPKRSTLKSRSDVELERQFTFKHSGQTWSGVPIIAANMDTVGTFEMASALASFDILTAVHKHYSVEDWNAFTSTASEDVLRHVMVSTGTSDADFEKTKQILAQSPALNFVCIDVANGYSEHFVQFVSKAREAWPTKTICAGNVVTGEMCEELVLSGADIVKVGIGPGSVCTTRVKTGVGYPQLSAVIECADAAHGLGGMIVSDGGCTMPGDVAKAFGGGADFVMLGGMLAGHEESGGKIVEENGEKFMLFYGMSSESAMTRHVGGVAQYRAAEGKTVKLPLRGPVEYTARDILGGLRSACTYVGASRLKELTKRTTFIRVQEQENRVFNSL
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
Protein: PRMA_CLOBM
Sequence: MDKEWLEVCIYTSSEALEAISGILYNTGVKGVSIEDPKDIEFKKKHPGDWDYFDETLLKVKDTAIVKGYYKEDDKFNEYLDYIKKSVSNLDQFGIDKGEGLVEVHKVNEEDWENNWKKYYKPTKVSNKIVIKPIWENYDKKQEEIIVELDPGMAFGTGTHETTRMCINALEKYIKEDRTVFDIGCGSGILSIAAAKLGAKHVIGVDLDPVAVKSSKENIKYNNLDNIEILEGNLMEVVEGRANIVVANIIADVIIFLTEGVKAFIEKGGYFIASGIINSRKEDVIKKLEETGFVIEEVREEGEWVCIISKIN
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ORC5_YEAST
Sequence: MNVTTPEVAFREYQTNCLASYISADPDITPSNLILQGYSGTGKTYTLKKYFNANPNLHAVWLEPVELVSWKPLLQAIARTVQYKLKTLYPNIPTTDYDPLQVEEPFLLVKTLHNIFVQYESLQEKTCLFLILDGFDSLQDLDAALFNKYIKLNELLPKDSKINIKFIYTMLETSFLQRYSTHCIPTVMFPRYNVDEVSTILVMSRCGELMEDSCLRKRIIEEQITDCTDDQFQNVAANFIHLIVQAFHSYTGNDIFALNDLIDFKWPKYVSRITKENIFEPLALYKSAIKLFLSTDDNLSENGQGESAITTNRDDLENSQTYDLSIISKYLLIASYICSYLEPRYDASIFSRKTRIIQGRAAYGRRKKKEVNPRYLQPSLFAIERLLAIFQAIFPIQGKAESGSLSALREESLMKANIEVFQNLSELHTLKLIATTMNKNIDYLSPKVRWKVNVPWEIIKEISESVHFNISDYFSDIHE
What is the function of this protein?
Component of the origin recognition complex (ORC) that binds origins of replication.  It has a role in both chromosomal replication and mating type transcriptional silencing.  Binds to the ARS consensus sequence (ACS) of origins of replication.  This subunit is a candidate for the mediation of ATP-dependent binding of ORC to origins.  May also be a substrate targeting component of a cullin-RING-based E3 ubiquitin-protein ligase complex RTT101(MMS1-ORC5).
What are the official names of this protein?
Origin recognition complex subunit 5, Origin recognition complex 53 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the ORC5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CALU_XENLA
Sequence: MNKRPLLLCLGLWVACTLSKPTEKKDRVHHDSQLSDKVHDDAQNFDYDHDAFLGAEDAKTFDQLTPEESKERLGMIVGKIDLDNDGYVTEGELTAWIKKAQKKYVYDNVERQWQEFDLSQDGLVSWDEYRNVTYGTYLDDQDPDNSFNYKQMMIRDERRFKMADKDGDLVATKEEFTAFLHPEEFDYMKDIVVLETMEDIDKNGDGLIDLEEYIGDMYNHDGDANEPEWVKTEREQFMEFRDKNHDGKMDKEETKDWILPSDYDHSEAESRHLVYESDHNQDGKLTREEIVDKYDLFVGSQATDFGEALVRHDEF
What is the function of this protein?
Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues.  Seems to inhibit gamma-carboxylase ggcx.  Binds 7 calcium ions with a low affinity (By similarity).
What are the official names of this protein?
Calumenin.
What is the protein family that this protein belongs to?
Belongs to the CREC family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane. Golgi apparatus. Secreted. Melanosome. Sarcoplasmic reticulum lumen.
Protein: HDAC1_STRPU
Sequence: MASTGTKKRVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLILNYGLYRKMEIYRPHKAVMEEMTKYHSDDYVKFLRTIRPDNMSEYTKQMQRFNVGEDCPVFDGLYEFCQLSSGGSVAGAVKLNKQQTDIAINWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPLRDGIDDESYDKIFKPIMCKVMEMYQPSAICLQCGADSLSGDRLGCFNLTLKGHAKCVEFMKQYNLPLLLMGGGGYTIRNVARCWTYETSTALGVEIANELPYNDYFEYFGPDFKLHISPSNMTNQNTGEYLDKIKTRLYENMRMIPHAPGVQMQPIPEDAIPDDSDAEDEAENPDKRISIMAQDKRIQRDDEFSDSEDEGETRLPGEGGRRDHRSHKAKRSKIDDSPGKEADKEAKSSDASKEAKPAAEPQAVPMDTTPAPPPKKSEDKPEASKPTEVKAKPAEKEPGEGEASPADLVVPVPKVSAPSEGATLPAVTIPPSSGTSQPPADPPVSAPTPTPASAPAEKQD
What is the function of this protein?
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4).  Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.  Histone deacetylases act via the formation of large multiprotein complexes (By similarity).
What are the official names of this protein?
Histone deacetylase 1, HD1.
What is the protein family that this protein belongs to?
Belongs to the histone deacetylase family. HD type 1 subfamily.
What are the subcellular locations of this protein?
Nucleus.