PharMolix/UniProtQA huggingface dataset:
Protein: 3BHS2_RAT
Sequence: MPGWSCLVTGAGGFVGQRIIRMLVQEKELQEVRALDKVFRPETKEEFSKLQTKAKVTMLEGDILDAQYLRRACQGISVVIHTASVMDFSRVLPRQTILDVNLKGTQNLLEAGIHASVPAFIYCSTVDVAGPNSYKKTILNGREEEHHESTWSNPYPYSKKMAEKAVLAANGSILKNGGTLHTCALRPMYIYGERGQFLSRIIIMALKNKGVLNVTGKFSIVNPVYVGNVAWAHILAARGLRDPKKSQNIQGQFYYISDDTPHQSYDDLNCTLSKEWGLRLDSSWSLPLPLLYWLAFLLETVSFLLRPFYNYRPPFNCHLVTLSNSKFTFSYKKAQRDLGYEPLVSWEEAKQKTSEWIGTLVEQHRETLDTKSQ
What is the function of this protein?
3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids.  The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids.
What are the official names of this protein?
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2, 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II, 3-beta-HSD II.
What is the protein family that this protein belongs to?
Belongs to the 3-beta-HSD family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein.
Protein: GMK2_ARATH
Sequence: MGEAPAFFVDHLENGYTNGFGVKSEPKNRDTSVLIGDRSFVIGGNHEGNPLFLGVQIHDKVTNKWSSPSVLGTGPKPCKGYSAIVLPKGRILVIKKGSASDDSIWFLEVDTPFIREQKKLLGREVVAWSKGVRGNAEKPIVISGPSGVGKGTLISMLMKEFPSMFGFSVSHTTRAPRCMEKNGVHYHFTDKTVMEKEIKDGKFLEFASVHGNLYGTSIESVEVVTDSGKRCILDIDVQGARSVKASSLDAIFIFVCPPSMKELEDRLRARGTETEEQIQKRLRNADAEIKAGKSSGIFEHKLYNDNLEECYKTLKNLLGINDLAPVNGVEVEGINLPKEHTVTKMDDKILIQETGEGTKNKMIVLDLSSINGGAPGRTRGIVLDTVKSS
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.  Required for normal development of the gametophyte and embryo, in association with GK1.
What are the official names of this protein?
Guanylate kinase 2, AtGK2, GMP kinase 2.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
Protein: 059L_FRG3G
Sequence: MPAQKRMSRYAYLVNKVAGPTLCGVFYGKYVEASDQAVSTCMAWFKIVVITKRVSAREWQEKGATVVTFRDLTRGTAPKAVECDLLYVRDFNPNTSQCWLPMLEGYKRTRTWVQIGHCNFESYGPHVMKKQLFGDFSYVPFVGYGSDVLALPETDEILEYDTSPFERFVHAVQRLNPKGESVWTHLGPDVAFAEMSIDAFNAVRESSPSPMSACMMDKTAVPQSLSEMVADYDWDHNEALRETPYVSSACAAMSRLTSSDPSLVVAVHEPKLQKYLEQFTGAKVVTYGKMLDSRMVPKRVVIFQAHPINGCKSGRKLMHMWRSMPGKPKITVIKPRQEWSAYYCNPLKRVGL
What are the official names of this protein?
Uncharacterized protein 059L.
Protein: RS8_PECAS
Sequence: MSMQDPIADMLTRIRNGQAANKVAVTMPSSKLKVAIANVLKEEGYIEDFKIEGDTKPVLELELKYFQGKAVVESIQRISRPGLRIYKRKDELPKVMAGLGIAVISTSKGVMTDRAARQAGLGGEIICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RL5_THESQ
Sequence: MRYEYVPLKDQYEKEIVPALMKEFNYKNIHQVPKLVKIVINMGIGEGSRNYDLIERHANELAKITGQKPIVTRARKSISNFKIRKGMPIGLKVTLRGARMYNFLYKLINIVLPKVRDFRGLDPNSFDGRGNYSFGLSEQLVFPELSPDEVRRIQGMDITIVTTAKTDQEARRLLELFGMPFKRG
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: RL24_METM7
Sequence: MVLTNSKQPRKQRKALYNAPLHLRNSVMAAMLSKELKEKFNKNSLPVKKGDTVKVLRGNFKGIEGEVSKVDYAGYKIIVEGVVNKKQDGTETAYPIHPSNVMITKLDESDEKRFKNSSN
What is the function of this protein?
Located at the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: PUR5_BURP6
Sequence: MNPPKSAPDAQGLSYRDAGVDIDAGDALVDKIKPFAKKTLRDGVLGGIGGFGALFEVPKKYREPVLVSGTDGVGTKLKLAFHLNKHDTVGQDLVAMSVNDILVQGAEPLFFLDYFACGRLDVETAATVVKGIATGCELAGCALIGGETAEMPSMYPDGEYDLAGFAVGAVEKSKIIDGSTIAEGDVVLGLASSGIHSNGFSLVRKIIERANPDLSADFHGRSLADALMAPTRIYVKPLLALMEKIAVKGMAHITGGGLVENIPRVLRDGLTAELDQHAWPLPPLFQWLQQHGGVADAEMHRVFNCGIGMAVIVSAADADDALRQLADAGEQVWKIGTVRASREGEAQTVVV
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KNOS1_ORYSJ
Sequence: MEDLYSIHPGISRVGGAASEASGVGVVVGGGGGSSSSDLTELMKAQIAGHPRYPTLLSAYIECRKVGAPPEVASLLKEIGRERRAGGGGGGAGQIGVDPELDEFMEAYCRVLVRYKEELSRPFDEAASFLSSIQTQLSNLCSGATSPPATTATHSDEMVGSSDEDQCSGETDMLDIGQEQSSRLADHELKEMLLKKYSGCLSRLRSEFLKKRKKGKLPKDARSALLEWWNTHYRWPYPTEEDKLRLAARTGLDPKQINNWFINQRKRHWKPSDGMRFALMEGVAGGSSGTTLYFDTGTIGP
What is the function of this protein?
Probable transcription factor that may be involved in shoot formation during early embryogenesis.
What are the official names of this protein?
Homeobox protein knotted-1-like 1, Homeobox protein HOS16, Homeobox protein OSH6.
What is the protein family that this protein belongs to?
Belongs to the TALE/KNOX homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MCA8_ARATH
Sequence: MAKKALLIGINYPGTAVELRGCVNDVHRMQKCLIELYGFANKDIVIMIDTDKSCIQPTGKNICDELDNLIASGQSGDFLVFHYSGHGTRIPPGIEDSEDPTGFDECITPCDMNLIKDQQFREMVSRVKEGCQLTIISDSCHSGGLIQEVKEQIGESHMKPVDKVKEQIEESHMKQPKLGIASYFLNIVMNLLATCGVSKSQRDRGGGEESFRGEIELEKDETLDIKTRYLPFESYLSLLKEQTGQTNIEPVRIRQTLLKLFGEDPSPNRQRGLSDLGNCEVDAGDSGASRLNAVTDNGILLSGCQTDQRSEDVYVTRTGKAYGAFSDAIQMILSAPRKDKKKITNKELVSEARVFLKKRGYSQRPGLYCHDRFVDKPFICY
What is the function of this protein?
Cysteine protease that cleaves specifically after arginine residues.  Does not cleave caspase-specific substrates.  May be involved in the modulation of programmed cell death activated by oxidative stress.
What are the official names of this protein?
Metacaspase-8, AtMC8, Metacaspase 2e, AtMCP2e.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14B family.
Protein: ATPA_BACC2
Sequence: MSIRAEEISALIKQQIENYQSEIEVSDVGTVIQVGDGIARAHGLDNVMAGELVEFSNGVMGLAQNLEENNVGIIILGPYTEIREGDEVRRTGRIMQVPVGKELIGRVVNPLGQPVDGLGPINTTNTRPIESPAPGVMDRKSVHEPLQTGIKAIDALVPIGRGQRELIIGDRQTGKTAVALDTIINQKDEDMICIYVAIGQKESTVRNVVETLRKHGALEYTIVVTASASQPAPLLYLAPYAGVTMGEEFMYNGKHVLVVYDDLSKQAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDARGGGSLTALPFIETQAGDVSAYIPTNVISITDGQIFLQSDLFFSGVRPAIDAGTSVSRVGGSAQIKAMSKVSGTLRLDLASYRELEAFAQFGSDLDKATQAKLNRGARTVEVLKQGLHKPLRVEKQVIILYALTRGFLDDIPVVDITRFEEEFHAWLDSNATDLLEEIRTTKKLADDDKFAAAINGFKKVFVASE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CLD3_MOUSE
Sequence: MSMGLEITGTSLAVLGWLCTIVCCALPMWRVSAFIGSSIITAQITWEGLWMNCVVQSTGQMQCKMYDSLLALPQDLQAARALIVVSILLAAFGLLVALVGAQCTNCVQDETAKAKITIVAGVLFLLAALLTLVPVSWSANTIIRDFYNPLVPEAQKREMGAGLYVGWAAAALQLLGGALLCCSCPPRDKYAPTKILYSAPRSTGPGTGTGTAYDRKDYV
What is the function of this protein?
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
What are the official names of this protein?
Claudin-3, Clostridium perfringens enterotoxin receptor 2, CPE-R 2, CPE-receptor 2.
What is the protein family that this protein belongs to?
Belongs to the claudin family.
What are the subcellular locations of this protein?
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.
Protein: GTR2_HUMAN
Sequence: MTEDKVTGTLVFTVITAVLGSFQFGYDIGVINAPQQVIISHYRHVLGVPLDDRKAINNYVINSTDELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLGDTLGRIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIAPTALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCPESPRYLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSYRQPILVALMLHVAQQFSGINGIFYYSTSIFQTAGISKPVYATIGVGAVNMVFTAVSVFLVEKAGRRSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLFTFFKVPETKGKSFEEIAAEFQKKSGSAHRPKAAVEMKFLGATETV
What is the function of this protein?
Facilitative hexose transporter that mediates the transport of glucose, fructose and galactose (PubMed:8027028, PubMed:16186102, PubMed:23396969, PubMed:28083649, PubMed:8457197).  Likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell (PubMed:8027028).  May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney (PubMed:3399500).  Also able to mediate the transport of dehydroascorbate (PubMed:23396969).
What are the official names of this protein?
Solute carrier family 2, facilitated glucose transporter member 2, Glucose transporter type 2, liver, GLUT-2.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS27_PYRAR
Sequence: MPVKFGKVLIPQPRSKFVKIRCPDCGNEQVTFSHAAMVVRCLVCGRVLAQPTGGKAKFAGHIVKILE
What are the official names of this protein?
30S ribosomal protein S27e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS27 family.
Protein: FEMB_STAAC
Sequence: MKFTELTVTEFDNFVQNPSLESHYFQVKENIVTRENDGFEVVLLGIKDDNNKVIAASLFSKIPTMGSYVYYSNRGPVMDFSDLGLVDYYLKELDKYLQQHQCLYVKLDPYWLYHLYDKDIVPFEGREKNDALVNLFKSHGYEHHGFTTEYDTSSQVRWMGVLNLEGKTPETLKKTFDSQRKRNINKAINYGVKVRFLERDEFNLFLDLYRETEERAGFVSKTDDYFYNFIDTYGDKVLVPLAYIDLDEYVLKLQQELNDKENRRDQMMAKENKSDKQMKKIAELDKQIDHDQHELLNASELSKTDGPILNLASGVYFANAYEVNYFSGGSSEKYNQFMGPYMMHWFMINYCFDNGYDRYNFYGLSGDFTENSEDYGVYRFKRGFNVQIEELIGDFYKPIHKVKYWLFTTLDKLRKKLKK
What is the function of this protein?
Catalyzes the formation of the pentaglycine interpeptide bridge, which is characteristic of the S. aureus peptidoglycan.  Adds glycines 4 and 5 of the pentaglycine bridge, using glycyl-tRNA(Gly) as donor.  Involved in resistance to methicillin (By similarity).
What are the official names of this protein?
Aminoacyltransferase FemB, Factor essential for expression of methicillin resistance B, N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-(N6-triglycine)-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine:glycine glycyltransferase.
What is the protein family that this protein belongs to?
Belongs to the FemABX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CASP2_BRADI
Sequence: MSSTSEATVIHMDGAAGKTPATAVPPPPPPAPTAPVQQQRKAGGVPFLLRSGAEGFRRCMALLDLLLRVAAMGPTLAAAISTGTSDETLSVFTHYFQFRARFDDFSAFTFFMVANAVAAGYLLMSLPFSAFGVIRPKATSVRLLLLICDTIMVVLVTAAASAAAAIVYVAHEGNRRANWVPICMQFHGFCKRTSGAVVASFLAVLIFILLVFLGACAIRRRHTTTKH
What is the function of this protein?
Regulates membrane-cell wall junctions and localized cell wall deposition.  Required for establishment of the Casparian strip membrane domain (CSD) and the subsequent formation of Casparian strips, a cell wall modification of the root endodermis that determines an apoplastic barrier between the intraorganismal apoplasm and the extraorganismal apoplasm and prevents lateral diffusion (By similarity).
What are the official names of this protein?
Casparian strip membrane protein 2, BdCASP2.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Very restricted localization following a belt shape within the plasma membrane which coincides with the position of the Casparian strip membrane domain in the root endodermis.
Protein: MNMC_PSEA6
Sequence: MTIKTADIQFNADGTPIATNFDDVYFSSFDGAAETEYVFLHNNLLPQRWQQWSKPTFVIAETGFGTGLNLLVTLAVFKQHLAQHPASTFTLHYISTEKFPLTHTDLVQALNAFVQFEDDAKALIAQYPMPLDGCHRMSFLNNRVIVDLWLGDIHDSLPQWHTNENGLVDAWYLDGFAPSKNPQMWSPQLFEQMARLASNGCTFATFTAAGFVKRGLRDAGFEVEKRKGHGRKREMLAGIIARELETKVNRQQARYYQRGAYMNSTSVNTRCAENHAQTALASKPKVAIIGAGIAGASMAYAMAKKGYDCDIYFNDATPAQGASGNPQAGFYPQLNVDASHASQINAHSFVYAANQYRQLQSQGFHFAHQWCGVLQLGFKPALAERYAKLTESQLWPGELVRYVKPSEAAQLANCEMPYSGLFMPLGGWIDPAQLVDALFDAAAKLSQVRLYSHHALNGIEQKNVSITAQENTRWQLHFEASEATSGMNKNTSLAQADIVIYATGAQSHDIAALADFPLRMVRGQVEAVPTQTALSKLNTVLCHKGYLTPEYNGQHALGSTYVKNDLSTDYRLSEQDKNLATHYQSLSDCQWAQEVVGNAQGRAAVRCSSPDHLPLVGALADIEKQKKELSDLYKALPLSYYPKGSNMNNVFVLTGLGSRGLTTAPLMAEVLASQISGQPLPMANDLLNTLNPNRFLIRQLIRREV
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UGPC2_AGRFC
Sequence: MAQIDIRQVRKSYGKTPTLHGVDLSFDSGEFVVILGPSGCGKSTLLRMIAGLEEITSGEIAIGGRVVNTLEPRERGCAMVFQNYALYPHMSVAANIGYALKVAGVPKAERQRRIEETAKIVGLSDYLERKPAALSGGQRQRVAMARAIIREPAVFLFDEPLSNLDAKLRVSMRAEIRKLHQRLSATSIFVTHDQVEAMTLADRLVVMNKGNVEQVGHPLDIYHRPASTFVASFIGSPAMNLFTTKVEVETPAVILSGTPVKLFPETALELRGRNVTVGIRPEQCVVSMDGPGVPAIVDFVEELGSGRIVHADIAGETFSAAIGEDLLVKPGQRIHLDLPTAHLHFFDPATGKRIETEGTAETARSKNETLLAV
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
sn-glycerol-3-phosphate import ATP-binding protein UgpC 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. sn-glycerol-3-phosphate importer (TC 3.A.1.1.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MSHC_CORDI
Sequence: MQSWPMPTIPSVPGKPAVLSLFDTSDQLIKPVEVDTPEVGVYVCGITPYDSTHLGHAATYLTFDLINRQLIDAGHRVHFVQNITDVDEPLFERALRDGVDWRELGSSQIDLFRSDMENLSVIPPRHYVGAMESIPEVIAMVETMLANGTAYIVESDSYRDIYASITATTQFGYESHYSRELMEQFFAERGGDPERVGKKDSLDALIWRAHRLGEPSWDAPFGAGRPGWHVECSAIATHHLGSHFAIQGGGSDLIFPHHEFSAAHAEATFGESRMAGHYVHTGMIGLDGTKMSKSLGNLVFVSRLTSEGYHPSDIRLGVFAGHYRDDRDWSTDLLTAAQERRQAWITAADNARDVQQVQQTIQKIRHLLANDLNTPAVLAEVDNWANLIPLNDSARTEAGRLMASGLDALLGVKI
What is the function of this protein?
Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
What are the official names of this protein?
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase, L-Cys:GlcN-Ins ligase, Mycothiol ligase, MSH ligase.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
Protein: TO1F_HADVE
Sequence: SAVCIPSGQPCPYSKYCCSGSCTYKTNENGNSVQRCD
What is the function of this protein?
Inhibits insect, but not mammalian, voltage-gated calcium channels (Cav).
What are the official names of this protein?
Omega-hexatoxin-Hv1f, Omega-HXTX-Hv1f, Omega-atracotoxin-Hv1f, Omega-AcTx-Hv1f.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 08 (Shiva) family. 01 (omega toxin) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LPOA_DICC1
Sequence: MLPLNSVRTHAGRLVPVMLAALFLAGCPSQAPQSPAMQQRVEGKAGASSDYYLQQMQQSSDDSKADWQLLAIHALIQEGKLPQAGNQLGTLPSQLGDKQRQEQRLLTAELAVAQNDMNAANTMLAQLDVKSLSPQQQERYYQAQIKAAQDRTSLTLIRAYIGLEPLLQGDAHQRNIDQTWTALTRLNQQDLSSMVINVDENTLQGWLDLLNLWQTKAQVPSDLQAAIEDWKKRYPRHPAAKQLPSQLGGTPPAAAAPTTGETAPTGGNAIALLLPLNGQAQAFANAIQQGFSAARSGQASLAMPAQPAQLAQAANNAAAATPGAPAVPSPASSTPSAVSPTPAAATTVMPALTAATAGTIPVKVYDTSNQALANVIAQAQKDGATTIVGPLLKNEVEQLPGLNPSLNVLALNQPEHIQPNPNICYFALSPEDEAADAAQFIHKQGKQHPLILAPRGNLGDRVVAAFAKSWQQQSGGVVLQQRTGSMYDLKQAINSGAGIPLNGQPVITAASAPQPSTTVGGLTIPNQAPPIAAVTSDGNVDAIYIIATPDELALLKPMIDMRNKGASRPALYASSRSYQAGLGPDFRFEMEGLQFSDIPLLTGASPALMQQVSTQFRNDYSLVRLFAMGMDAWKLASDFSQLHQPGSSLSGATGILSASSDCVVNRKLTWLQFRQGQLVPAS
What is the function of this protein?
Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a).
What are the official names of this protein?
Penicillin-binding protein activator LpoA, PBP activator LpoA.
What is the protein family that this protein belongs to?
Belongs to the LpoA family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor; Periplasmic side.
Protein: H4_SOLLC
Sequence: MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKIFLENVIRDSVTYTEHARRKTVTAMDVVYALKRQGRTLYGFGG
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H4.
What is the protein family that this protein belongs to?
Belongs to the histone H4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: DHQS_METTH
Sequence: MKFAWLLAPDTYWDEKKTFITAALESGIDHIVDTADSGRIKKLGNLTLISPDEDADIVLVGRDGEGDGTLELPETLEYSRDIEMASELSESGRQVAAYVEIRSKAHEELARRLGRVVDYLILVGEDWKIIPLENIIADLQEEDVKLIAAVADVDEARVALETLEHGTDGVLIEPADISQIKDIAALLENIESETYELKPATITRIEPIGSGDRVCVDTCSIMGIGEGMLVGSYSQGLFLVHSESLESEYVASRPFRVNAGPVQAYVMVPGGRTRYLSELETGDEVIIVDRDGRSRSAIVGRVKIEKRPLMLVEAEYEGMKVRTLLQNAETIRLVNDKGEPVSVSELGEGDRVLVYFDESARHFGMAIKETIIEK
What is the function of this protein?
Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3-dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis.
What are the official names of this protein?
3-dehydroquinate synthase, DHQ synthase, 3-dehydroquinate synthase II.
What is the protein family that this protein belongs to?
Belongs to the archaeal-type DHQ synthase family.
Protein: VATF_METVS
Sequence: MRIGVVGDSDVAVGFRLAGLTDVYEVKSPEQASKAIEELDNNAEIGLIITTERIGEGIRETIANAKKVIVEVPDKNGPIVREKDPVKILVRNAVGIDIK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit F, V-ATPase subunit F.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase F subunit family.
Protein: RHAM_ECOK1
Sequence: MIRKAFVMQVNPDAHEEYQRRHNPIWPELEAVLKSHGAHNYAIYLDKAHNLLFATVEIESEERWNAVASTDVCQRWWKYMTDVMPANADNSPVSSELQEVFYLP
What is the function of this protein?
Involved in the anomeric conversion of L-rhamnose.
What are the official names of this protein?
L-rhamnose mutarotase, Rhamnose 1-epimerase, Type-3 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose mutarotase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMN_SYNY3
Sequence: MTTTFPTVEFSAELLNKYNQGIPRYTSYPPATELNKEFDPSDFQTAINLGNYKKTPLSLYCHIPFCAKACYFCGCNTIITQHKPAVDPYLKAVAKQIALVAPLVDQQRPVQQLHWGGGTPNYLTLEQAEFLFNTITDAFPLAENAEISIEINPCYVDKDYIFALRQLGFNRISFGIQDFNSQVQQAVNRIQPEAMLFQVMDWIRQANFDSVNVDLIYGLPHQNLATFRETLRKTAQLNPDRIAVFNFAYVPWLKPVQKKMPESALPPAEEKLKIMQATIADLTEQGYVFIGMDHFAKPDDELAIAQRRGELHRNFQGYTTQPESDLLGFGITSISMLQDVYAQNHKTLKAFYNALDREVMPIEKGFKLSQDDLIRRTVIKELMCQFKLSAQELESKYNLGFDCDFNDYFAKELSALDVLEADGLLRRLGDGLEVTPRGRILIRNIAAVFDTYLQNKSKQQMFSRAI
What is the function of this protein?
Involved in the heme and chlorophyll biosynthesis.  Catalyzes the anaerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen III to yield the vinyl groups in protoporphyrinogen IX.
What are the official names of this protein?
Oxygen-independent coproporphyrinogen III oxidase, CPO, Coproporphyrinogen III dehydrogenase, CPDH.
What is the protein family that this protein belongs to?
Belongs to the anaerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LAC1_FOMPI
Sequence: MAFTAISLFLAALGVINTAFAQSAVIGPVTDLDIINAEVNLDGFPRQAVLAGGTFPGPLIKGNKGDNFRINVHDFLYNETMDVTTTIHWHGIFQRHTNWADGPAFVTQCPIAPGNSFLYNFTVPNQAGTFWYHSHEGLQYCDGLRGPFVVYDPEDPHRDLYDVDDESTVITLADWYHEAASLIVPPADPDSVLINGRGRQANDTTSPLAVINVEYGKRYRIRLISVSCDPYFNFTIDGHNFTIIEADGENTDPLPGVDQIQIFAAQRYSFILDANQPIDNYWIRVIPEQVGANGTAATPPGLAVLHYLGAPPFDPKANASQVPISVNPLLEQNLHALGATGVPDLDPSCAECNITLDFTFNTPLFFVNGVTYKSPTVPVLLQILNGSFTAQDLMPEGSVYTLPRNKTIQINMPGGVLGIPHPLHLHGHSFSVIRSANSDETNLYNPVRRDTVSIGTNGSFVAIRFTTDNPGPWFLHCHIDFHLAAGFAVVMAEDPMDVPGYVKPIPPAWDKLCPIYDALPANEQILQPEAANLSTYPQK
What is the function of this protein?
In vitro, has activity towards 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS), 2,6-dimethoxy-phenol, and guaiacol (PubMed:34116754).  Although brown rot fungi preferentially degrade hemicellulose and cellulose, the enzyme may contribute to generating small amounts of lignin breakdown products required for catalytic reactions (PubMed:34116754).
What are the official names of this protein?
Laccase-1, FpLCC1.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Secreted.
Protein: MNHC1_STAAW
Sequence: MEIIMIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANLFLITMGGLKHGTVPIYEANVKSYVDPIPQALILTAIVIAFATTAFFLVLAFRTYKELGTDNVESMKGVPEDD
What is the function of this protein?
Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.
What are the official names of this protein?
Na(+)/H(+) antiporter subunit C1, Mnh complex subunit C1.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FAD12_MORAP
Sequence: MAPPNTIDAGLTQRHISTSAAPTSAKPAFERNYQLPEFTIKEIRECIPAHCFERSGLRGLCHVAIDLTWASLLFLAATQIDKFENPLIRYLAWPAYWIMQGIVCTGIWVLAHECGHQSFSTSKTLNNTVGWILHSMLLVPYHSWRISHSKHHKATGHMTKDQVFVPKTRSQVGLPPKENAAAAVQEEDMSVHLDEEAPIVTLFWMVIQFLFGWPAYLIMNASGQDYGRWTSHFHTYSPIFEPRNFFDIIISDLGVLAALGALIYASMQLSLLTVTKYYIVPYLFVNFWLVLITFLQHTDPKLPHYREGAWNFQRGALCTVDRSFGKFLDHMFHGIVHTHVAHHLFSQMPFYHAEEATYHLKKLLGEYYVYDPSPIVVAVWRSFRECRFVEDHGDVVFFKK
What is the function of this protein?
Catalyzes the desaturation of oleic acid (Delta(9)-18:1) to linoleic acid (Delta(9), Delta(12)-18:2).
What are the official names of this protein?
Delta(12) fatty acid desaturase, Delta-12 fatty acid desaturase.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.