PharMolix/UniProtQA huggingface dataset:
Protein: MPAH1_HOLLA
Sequence: MASSSRSVLLLVAALFAVFLGSAHGIAKVPPGPNITATYGDEWLDAKSTWYGKPTGAGPKDNGGACGYKDVDKPPFSGMTGCGNTPIFKDGRGCGSCFEIKCTKPESCSGEPVTVHITDDNEEPIAPYHFDLSGHAFGSMAKKGEEQKLRSAGELELKFRRVKCKYPDGTKPTFHVEKGSNPNYLALLVKYIDGDGDVVAVDIKEKGKDKWIELKESWGAVWRVDTPDKLTGPFTVRYTTEGGTKGEAEDVIPEGWKADTAYEAK
What are the official names of this protein?
Major pollen allergen Hol l 1, Allergen Hol l 1.0101/1.0102, Allergen Hol l I.
What is the protein family that this protein belongs to?
Belongs to the expansin family. Expansin B subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MURB1_CORGL
Sequence: MNDFKKVSESLETALRNEFDFRFATEVSLKEISRWRIGGPAAVFAEPSSINEICALLAFMKNRPEPVVVVGGTSNILFDSDGFGGLVIKLGENFSNFIIEGSRIRAQAGASVPQLVRAVATEGLEGIVHAGGIPGTVGGLVVMNGGTQRRGIGEHVTKVLVTDAEGSIRELNANELQFTYRNSVLKNSETTVLEVELLLKPGNAGELLAELETILDQRSQKFPEDLPNCGSTFLSDPAMYSIVGPPGKAIEDAGLKGLRRGSAEISMQHANFIVNHGDASDDDILWLISAVRKEVYSRTGFVMDCEVLYLSYSGDFRPAHEVADEQWPDIDLVRN
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase 1, UDP-N-acetylmuramate dehydrogenase 1.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMFO_STAEQ
Sequence: MTQKVNVVGAGLAGSEAAYQLAQRGIKVNLIEMRPVKQTPAHHTDKFAELVCSNSLRGNALTNAVGVLKEEMRHLDSLIITSADKARVPAGGALAVDRHDFAGYITDTLRNHPNITVLNEEVNHIPEGYTIIATGPLTTEHLAQEIVDITGKDQLYFYDAAAPIIEKDSINMDKVYLKSRYDKGEAAYLNCPMTEEEFNRFYDAVLEAEVAPVNEFEKEKYFEGCMPFEVMAERGRKTLLFGPMKPVGLEDPKTGKRPYAVVQLRQDDAAGTLYNIVGFQTHLKWGAQKEVIRLIPGLENVDIVRYGVMHRNTFINSPDVLNEKYELKGHDNLYFAGQMTGVEGYVESAASGLVAGINLAHKILDKGEVIFPRETMIGSMAYYISHAKNEKNFQPMNANFGLLPSLEKRIKDKKERYETQAKRALEYLDNYKQTL
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CEND_PIG
Sequence: MESRGRSANSPKADAKATTEARAPPAVDGKVPSAKKQEAQKAEKQEPPAAPTLPPAKKTSALLDNHSNLKPAPAAPSSPDAAPEPKGPGDGAEEAEAPSGGPGGRGPCPFENLNPLLVAGGIAMAAAALILGVVFLARKK
What is the function of this protein?
Involved in neuronal differentiation.
What are the official names of this protein?
Cell cycle exit and neuronal differentiation protein 1, BM88 antigen.
What is the protein family that this protein belongs to?
Belongs to the CEND1 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type IV membrane protein. Endomembrane system; Single-pass type IV membrane protein. Note=Associated with the plasma membrane and the membranes of intracellular organelles.
Protein: FLIQ_SALTY
Sequence: MTPESVMMMGTEAMKVALALAAPLLLVALITGLIISILQAATQINEMTLSFIPKIVAVFIAIIVAGPWMLNLLLDYVRTLFSNLPYIIG
What is the function of this protein?
Required for the assembly of the rivet at the earliest stage of flagellar biosynthesis.
What are the official names of this protein?
Flagellar biosynthetic protein FliQ.
What is the protein family that this protein belongs to?
Belongs to the FliQ/MopD/SpaQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Bacterial flagellum basal body.
Protein: UREG_ACIB3
Sequence: MTERSPLRVGIGGPVGSGKTALTLNLCRALRDKYNMAVVTNDIYTKEDSNFLTRNEAMSPDRIVGVETGGCPHTAIREDASINLAAIDDLCEKFDGLELIIIESGGDNLAATFSPELSDLTLYVIDVAGGEKIPRKGGPGITKSDLLIINKTDLAPMVGANLDVMDQDAKRMRGEKPFLFSNMKTQDGLEEIIQFIEKQGLFKA
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVC_CHLT3
Sequence: MITLGVDPGSIVTGYGVIGKSEAGFRVFDYSAIRPGGKCDFPQRIKYIYDTLEKVICAYKPTQLSLETAFYGKNAQSALKLGQVRGAIIILAMNYNLKFVEYSPREVKKSVAGTGNASKEQVAYMVKKMLSIDDEKMALDTSDALAIALCGHFKSASMAASEFKKQSRKATSWGEYILQNPQVVVK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: PVH1_SCHPO
Sequence: MSNKSAWQPQFDEIHSSVQEAEGFLQSSNDVQKAIDEVHYPDSLNDLSEISKNLYISSWKTASELVSTSDKGIDYTLSAMSINPNLSVPEQQHLWLQIEDSSSQNILQYFEKSNKFIAFALSKNAKVLVHCFAGISRSVTLVAAYLMKENNWNTEEALSHINERRSGISPNANFLRQLRVYFECNYQLDRSLRPYRQWLFRRYGDFAVLNTRVPSEVAYAETVRARAGQLELRCKKCRFVLASSDYLVSHEPKDENNYSHTRCTHYFLEPIRWMQPELELGNLEGRFDCPKCNSKIGSYKWQGLQCSCLQWVCPALSILQSRVDAVRKLG
What is the function of this protein?
May be directly involved in signal transduction and/or cell cycle regulation.  It is necessary for maintaining growth rate or spore germination.  Could show both activity toward tyrosine-protein phosphate as well as with serine-protein phosphate (By similarity).
What are the official names of this protein?
Tyrosine-protein phosphatase yvh1, PTPase yvh1.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DAPF_ECO27
Sequence: MQFSKMHGLGNDFMVVDAVTQNVFFSPELIRRLADRHLGVGFDQLLVVEPPYDPELDFHYRIFNADGSEVAQCGNGARCFARFVRLKGLTNKRDIRVSTANGRMVLTVTDDDLVRVNMGEPNFEPSAVPFRANKAEKTYIMRAAEQTILCGVVSMGNPHCVIQVDDVDTAAVETLGPVLESHERFPERANIGFMQVVKREHIRLRVFERGAGETQACGSGACAAVAVGIQQGLLAEEVRVELPGGRLDIAWKGPGHPLYMTGPAVHVYDGFIHL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDHM_MOUSE
Sequence: MLSALARPAGAALRRSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETRANVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMVCIIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVDFPQDQLATLTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVQSKETECTYFSTPLLLGKKGLEKNLGIGKITPFEEKMIAEAIPELKASIKKGEDFVKNMK
What are the official names of this protein?
Malate dehydrogenase, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: ANMK_STRAW
Sequence: MRVIGLMSGTSYDAIDAAAADLGLAGDRLVLKPLGLMSEAYDSGLREELAAALPPAATSLAGVCRLDTRIGQAFAAAAVRADRELCGGRAELVASHGQTVYHWAEAGRVYGTLQLGQPAWIAEATGLPVVADFRPRDIAAGGQGAPLVSLVDLLWLRGRAGTSVALNLGGIANLTAPDGTAFDTGPACALIDAAAHGLSGGRLDHDVDGALAARGTVHEPMLRRLLAEPYYALPAPKTTGKELFHLGYLRDALAGFGTLTAEDVIATLTRLTALTVADAVRAVRATEVVASGGGTRNPVLMEMLARELGAVALRTSDELGLPSAAKEAYAFAVLGFLTVHGLAGTDPVSTGARHPSVLGSVTPGRDGLRLPPRADWSPVRLVLE
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: DACT2_DANRE
Sequence: MLGRKIPGSGVLGAGAGMDRGRTGERLHAALAGLQELHFLRDKQSAMVHWALTLNRDQPDPSKQENVSKEELRLEATLSLLKQQLTRLRRQDVGLKTHLQQLDQQITELKLDVCKASTEHLESDSRPSSGFYELSDGGSGSLSNSCTSVYSESLSSSSQTSLLPLLSTSYASHGRSSCGQTGVSRRCSADESTAQSDAPRSGVKLGSSLIRTATARADRARQRPVSTGDLDRMIGPGFGAFKSTDVKSSTPCSSPQNPSVDPKYQSNLVSSNGTEVYRYPSPLHAVALQSPIFSCTSDQGSSVALDEMPEEETQNLNEESTISSSVGYINKLLQRSSSRVNLLSSIKRIETVSGTHEQIPRSQEMIYGSLNGPQLLGSLQQLSMPLENALETGKTSALNNNQKQMDPPCLGSNFKEVEVQMLHHGKHPESSLDLQKNNFPINNTAGKVGAESDNGASEKRSGHFPKDLSVVQKPVERKSSFTSGREGSRASCHDKSSIPQSEFVHAQFVPAGSQRVKVRQADKKTKSVKLRKKSSEKPSAKKQHQKPLSREFCTKNRTDLKQSGSCRGKVTYLEESQAQSCSDCSCNGLINSHCIQNNHQQIPSSKSTKSRKAPEPVYHPLDHAKKKPSSRKWPSSSEIPLPPTLHTQRSKEMLNSRKVAMVRSVSARPRSGHWGCPPPRALPHSLSTSSYFSYLESRYPAAPVSSRHPPRCESEFSEYSAECASLFHSTIAASSDGEMSDYTTNRFGDSESSQGSQTASESDSSLSLDEEDLLEEEEEDEGGLVWAQAAMGTTAAGFSLQQHHRSESAACRIKASRALKKKIRRFQPASLKVMTLV
What is the function of this protein?
Involved in regulation of intracellular signaling pathways during development.  Specifically thought to play a role in canonical and/or non-canonical Wnt signaling pathways through interaction with DSH (Dishevelled) family proteins.  Positive regulator of the Wnt signaling pathway which acts downstream of wnt1 indicative for non-canonical Wnt signaling.  Also negatively regulates the Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors.  Required for convergent extension movements in gastrulation.
What are the official names of this protein?
Dapper homolog 2, Frodo 2.
What is the protein family that this protein belongs to?
Belongs to the dapper family.
What are the subcellular locations of this protein?
Cytoplasm. Late endosome. Nucleus. Cell membrane. Note=Predominantly cytoplasmic. Also found in late endosomes, the nucleus and at the cell membrane.
Protein: AIM6_ARTBC
Sequence: MKSSILASAAILAASLEPVAALSEPLQNILINTDRSPIYRYPTDVTRGIVPIPVHSHNDYWRDIPFYTALTTKLALSAGCISIEADVFLFNDTLYVGHEESALTKERTLQSLYIEPLMNVLKKTNPKSPFVSGPTRHGVFDTSSGQTLYLWIDVKNDGEKAWPHIVKALQPLRDANYLTKIQNNESFVPGPVTVIGTGGTPLSQVVSAADRDYFYDGPLKDLTGFTSLISPIASTSLMEVVGDIKSDSENPLNPTQLEAIRKQIKAAKEKSIGVRYWETPGWPIRLRNELWRTLWKEGVALLNADDVNAAKGYF
What are the official names of this protein?
Altered inheritance of mitochondria protein 6 homolog ARB_06966.
What is the protein family that this protein belongs to?
Belongs to the AIM6 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL27_HERA2
Sequence: MAHKKGVGSSRNGRDSKPQMRGIKRFGGELVQPGSIIVRQCGTKVRPGANVGLGRDYTIYSMIDGHVKFEDYSRTQKMVSVVPAEAEA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: EVC_HUMAN
Sequence: MARGGAACKSDARLLLGRDALRPAPALLAPAVLLGAALGLGLGLWLGCRAGRQRTRHQKDDTQNLLKNLESNAQTPSETGSPSRRRKREVQMSKDKEAVDECEPPSNSNITAFALKAKVIYPINQKFRPLADGSSNPSLHENLKQAVLPHQPVEASPSSSLGSLSQGEKDDCSSSSSVHSATSDDRFLSRTFLRVNAFPEVLACESVDVDLCIYSLHLKDLLHLDTALRQEKHMMFIQIFKMCLLDLLPKKKSDDELYQKILSKQEKDLEELEKGLQVKLSNTEMSGAGDSEYITLADVEKKEREYSEQLIDNMEAFWKQMANIQHFLVDQFKCSSSKARQLMMTLTERMIAAEGLLCDSQELQALDALERTMGRAHMAKVIEFLKLQVQEETRCRLAAISHGLELLAGEGKLSGRQKEELLTQQHKAFWQEAERFSREFVQRGKDLVTASLAHQVEGTAKLTLAQEEEQRSFLAEAQPTADPEKFLEAFHEVLERQRLMQCDLEEEENVRATEAVVALCQELYFSTVDTFQKFVDALFLQTLPGMTGLPPEECDYLRQEVQENAAWQLGKSNRFRRQQWKLFQELLEQDQQVWMEECALSSVLQTHLREDHEGTIRGVLGRLGGLTEESTRCVLQGHDLLLRSALRRLALRGNALATLTQMRLSGKKHLLQELREQRALEQGSSQCLDEHQWQLLRALEARVLEEASRLEEEAQQTRLQLQQRLLAEAQEVGQLLQQHMECAIGQALLVHARNAATKSRAKDRDDFKRTLMEAAVESVYVTSAGVSRLVQAYYQQIGRIMEDHEERKLQHLKTLQGERMENYKLRKKQELSNPSSGSRTAGGAHETSQAVHQRMLSQQKRFLAQFPVHQQMRLHAQQQQAGVMDLLEAQLETQLQEAEQNFISELAALARVPLAESKLLPAKRGLLEKPLRTKRKKPLPQERGDLGVPNNEDLASGDQTSGSLSSKRLSQQESEAGDSGNSKKMLKRRSNL
What is the function of this protein?
Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling.  Involved in endochondral growth and skeletal development.
What are the official names of this protein?
EvC complex member EVC, DWF-1, Ellis-van Creveld syndrome protein.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Cytoplasm, cytoskeleton, cilium basal body. Cell projection, cilium. Cell projection, cilium membrane. Note=EVC2 is required for the localization of EVC at the base of primary cilia. The EvC complex localizes at the base of cilia in the EvC zone of primary cilia in a EFCAB7-dependent manner.
Protein: TRMN6_YERE8
Sequence: MTNVGEQLKKKPMLRGGGFTFKQFFVAHDRCAMKVGTDGVLLGAWVPVEKARKVLDIGCGSGLIALMIAQRSTPEVMIDGVELEPEAAQQASSNAAQSPWAERVHIYQQDVHQFAENHLHQYDLIVSNPPYFAPAVACRDEARDTARYTGSLTHDALLNCAEKLITEDGIFCVVLPHDLGEELSRLAVQQNWFIRCQVDIRDRPGKPLHRILLTLSRQAGETEFQQLDLRQSEGVYSPEFCALISDFYLNY
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MGSA_HAEIG
Sequence: MHTTTRTLTQHKRIALVAHDSCKKNLLNWTQKHKEALKPHILYATGTTGHILERETGLSIQSLLSGPMGGDQQLGGLIAEKKIDMMIFFWDPMNAAPHDPDVKALMRIATVWNIPVAINQSSADFLLTSVLFEQDVEIDVPDYEGYLKERLA
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: RLMH_PSEPK
Sequence: MRLRLIAVGSRMPKWVEEGWHEYAKRLPAELSLELVEIPLNTRGKNADVARLIRQEGEAMLSKVQPGERIVTLEVHGKPWSTEQLATELDRWRLDARTVNLMVGGPEGLAPEVCARAEQRWSLSPLTLPHPLVRILIGEQIYRAWTVLSGHPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STPAP_AILME
Sequence: MAAVDLDVQSLPRGGFRCCLCHVTTANRPSLDAHLGGRKHRHLVELRATRKAQGLRSVFVSGFPRDVDSAQLTQYFQAFGPVASVVMDKDKGVFAIVEMGDVGTREAVLSQPQHTLGGHRLRVRPREQKEFQSPASKSPKGAAPDSHQLTKALAEAPDVGAQMVKLVGLRELSEAERQLRNLVVALMQEVFTEFFPGCVVHPFGSSINSFDVHGCDLDLFLDLGDLEESQPAPKAPESPSLDSALASPLDPQALACTPASPPDSQPPSPQDSEALDFETPSSSLAPQTPDSALASETLASPQSLPPASPLQEDRGEGDLGKALELAEALSGEKTEGVAMLELVGSILRGCVPGVYRVQTVPSARRPVVKFCHRPSGLHGDVSLSNRLALHNSRFLSLCSELDGRVRPLVYTLRCWAQGRGLSGSGPLLSNYALTLLVIYFLQTRDPPVLPTVSQLTQKAGEGEQVEVDGWDCSFPRDASGLEPSTNKEPLSSLLAQFFSCVSCWDLRGSLLSLREGQALPVAGDLPSNRWEGLRLGPMNLQDPFDLSHNVAANVTSRVAGRLQNSCQAAANYCRSLQYQRRSSRGRDWGLLPLLQPSSPSSLLSATPIPLPPAPFTQLTAALAQVLREALGCHIEQGTKRLRSDRGGPEESPQGGTSKRLKLDGEEKSCEEGREEQQGYIRDHSEDGVEEMVVEVGEMVQDWVQSPGRPGEPPQMLREQLATGEEGQSGHAALAEQGPKGPEAAREGSQGETGRGVSLSSVSWRCALWHRVWQGRRRARRRLQQQTKERGRGSAGTAEWLAVEAQVTRELRGLSSAAQRPEAEPLLTFVASASQVNQTLTVTPIQDSQGLFPDLHHFLQVFLPQALRNL
What is the function of this protein?
Poly(A) polymerase that creates the 3'-poly(A) tail of specific pre-mRNAs.  Localizes to nuclear speckles together with PIP5K1A and mediates polyadenylation of a select set of mRNAs, such as HMOX1.  In addition to polyadenylation, it is also required for the 3'-end cleavage of pre-mRNAs: binds to the 3'UTR of targeted pre-mRNAs and promotes the recruitment and assembly of the CPSF complex on the 3'UTR of pre-mRNAs.  In addition to adenylyltransferase activity, also has uridylyltransferase activity.  However, the ATP ratio is higher than UTP in cells, suggesting that it functions primarily as a poly(A) polymerase.  Acts as a specific terminal uridylyltransferase for U6 snRNA in vitro: responsible for a controlled elongation reaction that results in the restoration of the four 3'-terminal UMP-residues found in newly transcribed U6 snRNA.  Not involved in replication-dependent histone mRNA degradation.
What are the official names of this protein?
Speckle targeted PIP5K1A-regulated poly(A) polymerase, Star-PAP, RNA-binding motif protein 21, RNA-binding protein 21, U6 snRNA-specific terminal uridylyltransferase 1, U6-TUTase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B-like family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus speckle.
Protein: MATK_TRIFR
Sequence: MKEYRVYLERARSRQQDFLYPLIFREYIYGLAYSHNFNRSIFVENGGYDNKYSLLNVKRLITRMYQQNHLIISTNDSNKNPFLVYNKNFYSQIISEGFAIVVEIPFFLQLSSSLEEAEIIKSYKNVRSIHSIFPFLEDKFTYLNYVSDIRIPYPIHLEILVQILRYWVKDVPFFHLLRXFLYDFCNWNCFTSTKKSISTFSKSNPRLFLFLYNFYVCEYESIFLFLRNKSSHLRLKSFSVFFERIFFYAKRKHLVEVFSKDFSYTLPFFKDPNIHYVRYQGKCILASKNVPFLMNKWKHYFIHLWQCFFDVWSQPRTIDINQLSEHSFQLLGYFSNVRLNRSVVRSQMLENTFLIEIVSKKLDIIVPIIPLIRSLAKAKFCNVLGHPISKPVWADSSDFDIIERFLRICRNLSHYYNGSSKKKSLYRIKYILRLSCIKTLACKHKSTVRAFLKRSGSEELLEEFFTEEEEILSLIFPRDSFTLHRFHRNRIWYLDILFSNDLVNDE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HEM4_PSEAE
Sequence: MSGWRLLLTRPDEECAALAASLGEAGVHSSSLPLLAIDPLEETPEQRTLMLDLDRYCAVVVVSKPAARLGLERLDRYWPQPPQQTWCSVGAATAAILEAYGLDVTYPEQGDDSEALLALPAFQDSLRVHDPKVLIMRGEGGREFLAERLRGQGVQVDYLPLYRRRAPDYPAGELLARVRAERLNGLVVSSGQGLQNLYQLAAADWPEIGRLPLFVPSPRVAEMARELGAQRVIDCRGASAPALLAALTSAA
What is the function of this protein?
Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
What are the official names of this protein?
Uroporphyrinogen-III synthase, UROS, Hydroxymethylbilane hydrolyase [cyclizing], Uroporphyrinogen-III cosynthase.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen-III synthase family.
Protein: SECA_STAS1
Sequence: MGFLSKIADGNKKEIKRLGKLADKVLALEEDMSILTDEEIKAKTSAFQEKLQSEEDIKKQNKILDDILPEAFALVREGSKRVFNMIPYKVQVMGGIAIHGGDISEMRTGEGKTLTATMPVYLNALTGRGVHVITVNEYLSSVQSQEMAELYEFLGLSVGLNLNSKTTTEKREAYACDITYCTNNELGFDYLRDNMVNYAEERVMRPLNFAIIDEVDSILIDEARTPLIISGEAEKSTSLYTQANVFAKMLKSEDDYNYDEKTKAVQLTEQGIDKAERMFKIDNLYDVNNVDVISHINTALRAHVTLQRDVDYMVNKGEVLIVDQFTGRTMPGRRFSEGLHQAIEAKEGVKIQNESKTMASITFQNYFRMYNKLSGMTGTAKTEEEEFRNIYNMTVTQIPTNKPVQRVDKPDLIYISQKGKFDAVVQDVIEKHKAGQPVLLGTVAVETSEYISNLLKKNGVRHDVLNAKNHEREADIVAGAGQRGAVTIATNMAGRGTDIKLGDGVQELGGLAVIGTERHESRRIDDQLRGRSGRQGDKGDSRFYLSLQDELMVRFGSERLQNMMNRLGMDDSTPIESKMVSRAVESAQKRVEGNNFDARKRVLEYDDVLRKQREIIYGERNSIIDSDESGGLVNDMLRSTLERSVNYYVNEEADDPDYEPFINYVDDVFLNEGDIKVEDIKGKDNEDIFEFVWNKVEIALKDQKEKIGTQFDEFERMILLRSIDTHWTDHIDTMDQLRQGIHLRSYGQQNPLRDYQNEGHQLFDTMMQNIEEDVSKYILKSVVSVEDDLERDKTTDFGKAEHVSAEDGKEKAKAEPYVKDEHIGRNDPCPCGSGKKYKNCHGA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: NOE4_RHIML
Sequence: MDRRVVITGMGGLCGLGTDTTSIWKWSARRRSAIGPVLNTELHGLKGIVGAEIKALPDHNIDRKQLVSMDRISVLAVIAAHEAMRQAGLSCNEGNALRFGATVGVGLGGWDATEKAYRPSLSTGGRTEIFTGVKAMPSAAACQVSMSLGLRGPVFGVTSACSSANHAIASAVDQIKCGRADVMLAGGSDAPLVWIVLKAWEAMRALAPDTCRPFSAGRKGVVLGEGAGMAVLESYEHATARGATILAEVAGVGLSADAFHITAPAVHGPESAMRACLADAGLNAEDVDYLNAHGTGTKANDQNETTAIKRVFGDHAYSMSISSTKSTHAHCIGAASALEMIACVMAIQEGVVPPTANYREPDPDCDLDVTPNVPRERKVRVAMSNAFAMGGTNAVLAFKQV
What is the function of this protein?
Proposed to synthesize NOD factor fatty acyl chain.  Involved in the synthesis of a highly unsaturated fatty acid moiety, which forms part of a lipo-oligosaccharide that is responsible for host specificity.
What are the official names of this protein?
Nodulation protein E, Host-specificity of nodulation protein B.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: HIS22_BRADU
Sequence: MSDSLERLYLAVLAARDLDPATSRTARLFQRGPSKMAKKLAEEAIEVVIDAVNGDTDAVVRESADLLYNLTVLWASAGVRPEDVWREMTRREDMLGIAEKLPKSAMKLPKVASPRVAARRPIVALEGRTARKRH
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase 2, PRA-PH 2.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_BURP0
Sequence: MPRRREVPKREVLPDPKYGNVDVAKFMNMLMLSGKKSVAERIVYGAFEQIQTKGGKDPLEVFTVALNNVKPVVEVKSRRVGGANYQVPVEVRPSRRMALAMRWLREAAKKRSEKSMALRLAGELSEAAEGRGGAMKKRDEVHRMAEANRAFSHFRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: CYAY_SALTI
Sequence: MNDSEFHRLADALWLTIEERLDNWDGDSDIDCEINGGVLTLSFENGSKIIINRQEPLHQVWLATKQGGYHFDLKGDEWVCDRSGETFWDLLEQAATQQAGEKVSFR
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: RL9_GEOSM
Sequence: MKLILKENVDNLGHIGDIVKVAPGYARNFLLPKGFAIEATEKNAKALEHAKRHLEYKKNKVLEAAKQLAAKIEGLSLSIAHQAGADDRLFGAVTNMELAEQLKANGIEVDRKRIVLAEPIKQLGDFTATVKIHPEVSATLKVAVTKA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.