PharMolix/UniProtQA huggingface dataset:
Protein: NIF3L_BOVIN
Sequence: MLSSRVRLVATTARLVHSLIYSSSRSFMDLKALLSSLNDFASLSFAESWDNVGLLVEPSPPHTVNTLFLTNDLTEEVMEEALQKKADLILSYHPPIFRPMKRITWKTWKERLVIRALENRVGIYSPHTAYDAAPQGVNNWLAKGLGVCTSRPIHPSKAPDYPTEGTHRVEFSVTHTQDPDKVISALKEIAGVSVTSFSARTDDEEQTRLSLNCTQQALMQVVAFLSQNRQFYQKTEILSLEKPLLLYTGMGRLCTLDESVSLETMIERIKSHLKLSHVRLALGIGKTLESPVKVVALCAGSGSSVLQGTDADLYLTGEMSHHDVLDAASQGISVILCEHSNTERGFLSDLRDMLDAHLENKINIILSETDRDPLHVI
What is the function of this protein?
May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation.
What are the official names of this protein?
NIF3-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Interaction with COPS2 may regulate localization to the nucleus.
Protein: ISF1_YEAST
Sequence: MIASEIFERGVQDPFCQDCDYEDETDVQSFLGSNDLNDFVNSKLASFSFQNSSKSNNSHHSSSTNAGNTSRHIGNHTIGHHLRKIKTAPHHLYGFVPANSTNNSNEPIRPSPRRIRANSSTLIHQLSRQSTRQSSLGDAADSCFDHKCIKPRSRHSSCYGIPTHLYGLEKYVSSELDSLAVANDQSNDLTSPLTSVSTPASNSNSYLNLNSSSAAYPSSYLSNEKNNRLKLISHGKISSNNVPGHSGNLNHYHRERTPSNLRRESFSLLSNGSSSSPLQTRNNSYSNSLVKSPSNSSLNTSVASSNEESSPHTSNCLEERNPRRKSFIKLSLASSFSN
What is the function of this protein?
Could influence the NAM7/UPF1 function, possibly at the level of mRNA turnover.  Participates in mitochondrial biogenesis.
What are the official names of this protein?
Increasing suppression factor 1, Mitochondrial biogenesis regulation protein 3.
What is the protein family that this protein belongs to?
Belongs to the ISF1/MBR1 family.
Protein: RIFL_AMYMS
Sequence: MSVRAAVVGLGWAGRELWLPLLREHADFEVVAAVDADPASRQAFTKATGIPTHAAVSALTAREVDLAVVAVPNYLHTEVAGALLATGISVFLEKPVCLNSAEIDVLAAAERSGGMLLAGSAARYRGDVGALRRLLPELGEIRHVALGWIRARGVPRAGGWFTQREKAGGGALYDLGWHLLDTLAFLLGPAAFTQVIGVTSDDFVNAGAWRAAWRQDQLGADAADVEDTARGFLVRDDGVSVSLRASWASHQARDVSVIHVEGSAGTADLRCTFGFSPNREPEPVLSVTREGTTTRLPVPLERIGVEYTRQVSDLAAMLADPGHRGRAVAEARPIVSMIENFYASAGSARGRGAVPAYQ
What is the function of this protein?
In a complex with RifK, RifL may catalyze the oxidation of UDP-glucose to UDP-3-keto-D-glucose, which would then be used by RifK to produce UDP-kanosamine.  Is not able to use dTDP-glucose as substrate.
What are the official names of this protein?
Putative UDP-kanosamine synthase oxidoreductase subunit, UDP-glucose 3-dehydrogenase.
Protein: MGSA_SALPC
Sequence: MELTTRTLPTRKHIALVAHDHCKQMLMNWVERHQPLLEKHVLYATGTTGNLIQRATGMDVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVSTADFIIQSPHFNDAVDILIPDYARYLAERLK
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: SF3BA_ARATH
Sequence: MQASDRFNINSQLEHLQAKYVGTGHADLSRFEWTVNIQRDSYASYIGHYPMLSYFAIAENESIGRERYNFMQKMLLPCGLPPEREDE
What are the official names of this protein?
Uncharacterized protein At3g23325.
What is the protein family that this protein belongs to?
Belongs to the SF3B5 family.
Protein: TRPD_PSET1
Sequence: MSIQTKQNINVLSANMHNASIQTAIEQLISNQSLSYTQSKALFDEIMQGNMSDIELSALLIALKSKGEISDEIAGAAASMRENALAFNTTRNQLADCCGTGGDGSNTINISTTAAIVAAAAGINMVKHGNRSVSSNSGSADLLKALGINIEMTPAQAANCLEQTGFTFLFAPQYHPGVRHAMGVRTALKTRTIFNILGPLVNPAAPEVQLLGVYNPNLCLPMAQTLRTLGTKRAMIVHGSGTDEIALHGPTTVVELNNGNISEYTLNPSDFDLANYSLEQLTGEGPQYNANVSLAILQGKGDEAHNAAIIVNVAALLYLSGKAQSLKDGAHKVHTLLSSGQAMNTLNAIIEVSNG
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: KEFG_SHIFL
Sequence: MSQPAKVLLLYAHPESQDSVANRVLLKPATQLSNVTVHDLYAHYPDFFIDIPREQALLREHEVIVFQHPLYTYSCPALLKEWLDRVLSRGFASGPGGNQLAGKYWRNVITTGEPESAYRYDALNRYPMSDVLRPFELAAGMCRMHWLSPIIIYWARRQSAKELASHARAYGDWLANPLSPGGR
What is the function of this protein?
Regulatory subunit of a potassium efflux system that confers protection against electrophiles.  Required for full activity of KefB.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system ancillary protein KefG, Putative quinone oxidoreductase KefG.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: KTHY_METMA
Sequence: MRGKLITLEGIDGSGKSTVAKKIQENPEIQVFDPVFTREPTRGTLTGTAVENAIQSETDQLAELFLFTADHAEHLAKLVKPALANGKNVISDRYSDSRYAYQGVTLKSRFENPLEWVRSLHSGWTVVPDLTFLFDIEPEIAVERCGKRGEQTKFEKIEFLQNVRENFLILAAEDPGRFVVIDASRPQEEVEKKVIKKVLEFIQRIS
What are the official names of this protein?
Probable thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: DBP9_SCHPO
Sequence: MEKSGGIREESSEKTFSDFNLDPRLQRAIHKCEFEKPTSVQSETIPLALEGKDLVAQARTGSGKTAAYLIPILELLLKQKQIDENQRGIFALLLVPTRELAQQVYNVLEKLTAFCSKHIRFINVATNSSDTVQRPLLLDLPDIVIATPSRCVVHVASGVLPLDKLKFLVIDEADLMLSFGYNEDMKTLSRSLPRGTQSFLMSATLSKNIASLQKLVCRNPFILAVKDKEASGKLTQYVVKCSEQDKFLLAYILLKLRLIKGKILIFVNEINRCYRLKLFLEQFGLKSLVLNSELPVNSRLHILEQYNKGLYQIIIATDESGMMGEIEELENNVDFVEEEVISTDQPTLDKMKDQENADVNDESILAAAKDKSKKKKRVKQDKEYGVARGLDFENVACVLNFDMPSNTKSYIHRIGRTARAGKPGTAMSFVVPKSEVGKHKPTSLESCKKDESVLRRLEKKQISLQPYSFDKNQIDAFRYRMEDALRAVTTVAVSAARAAELKQELLISEKLKSYFAENPDELLSLTHDTVSSVRLGHTQRHLRHVPEYLLPKGMQAVNKDIGFVPFKKNNRRKVFKSRKNPKHRHDPLRSMKRKS
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase dbp9.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX56/DBP9 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RLF4_ARATH
Sequence: MGVKMLLIFGLLILAMVAKSVNATYPLTKSCINGQGCIGEDDELESLMDSETNRRQLARGRRYIGYDALKKNNVPCSRRGRSYYDCKKRRRNNPYRRGCSAITHCYRYAR
What is the function of this protein?
Cell signaling peptide that may regulate plant stress, growth, and development.  Mediates a rapid alkalinization of extracellular space by mediating a transient increase in the cytoplasmic Ca(2+) concentration leading to a calcium-dependent signaling events through a cell surface receptor and a concomitant activation of some intracellular mitogen-activated protein kinases (By similarity).
What are the official names of this protein?
Protein RALF-like 4.
What is the protein family that this protein belongs to?
Belongs to the plant rapid alkalinization factor (RALF) family.
What are the subcellular locations of this protein?
Secreted.
Protein: PIP24_ORYSJ
Sequence: MGKEVDVSTLEAGGARDYIDPPPAPLVDVDELGKWSLYRALIAEFVATLLFLYVTVATVIGYKHQTDAAVNGADAACGGVGVLGIAWAFGGMIFILVYCTAGVSGGHINPAVTLGLFLARKVSLVRALLYMAAQCLGAICGVALVKGFQSSLYDRYGGGANELAAGYSTGTGLAAEIIGTFVLVYTVFSATDPKRNARDSHVPVLAPLPIGFAVFMVHLATIPITGTGINPARSLGVAVVYNNNKAWSDQWIFWVGPFIGAAIAALYHQVILRASARGYGSFRSNA
What is the function of this protein?
Water channel required to facilitate the transport of water across cell membrane.  May play a role in root water uptake.
What are the official names of this protein?
Aquaporin PIP2-4, OsPIP2;4, Plasma membrane intrinsic protein 2-4.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family. PIP (TC 1.A.8.11) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MGDG1_ARATH
Sequence: MQNPSTVTQESAAPVFDFFPRLRGLTSRNRSPCSNSDGYALSSSNALYFNGFRTLPSRRMGKTLASLSFNTKSSAGSSLRRFISDFNSFIRFHCDKVVPESFASVGGVGLSSDENGIRENGTGGVLGEEGLPLNGVEADRPKKVLILMSDTGGGHRASAEAIRAAFNQEFGDEYQVFITDLWTDHTPWPFNQLPRSYNFLVKHGTLWKMTYYGTSPRIVHQSNFAATSTFIAREIAQGLMKYQPDIIISVHPLMQHVPLRVLRSKGLLKKIVFTTVITDLSTCHPTWFHKLVTRCYCPSTEVAKRAQKAGLETSQIKVYGLPVRPSFVKPVRPKVELRRELGMDENLPAVLLMGGGEGMGPIEATARALADALYDKNLGEAVGQVLIICGRNKKLQSKLSSLDWKIPVQVKGFITKMEECMGACDCIITKAGPGTIAEAMIRGLPIILNGYIAGQEAGNVPYVVENGCGKFSKSPKEISKIVADWFGPASKELEIMSQNALRLAKPEAVFKIVHDMHELVRKKNSLPQLSCTA
What is the function of this protein?
Involved in the synthesis of the major structural component of photosynthetic membranes.  Required for proper thylakoid membrane biogenesis.  Does not discriminate between prokaryotic (18:1/16:0) or eukaryotic (18:2/18:2) 1,2-diacylglycerol species, but operates with some preference for the prokaryotic one.  Is responsible for most galactolipid synthesis in chloroplasts (PubMed:10869420, PubMed:11171188, PubMed:11553816, PubMed:17940034).  Required for the formation of thylakoid membranes and functional photosynthetic electron transport during cotyledons greening in young seedlings (PubMed:25253888).  May link galactolipid synthesis with the coordinated transcriptional regulation of chloroplasts and other organelles during cotyledon greening (PubMed:25253888).
What are the official names of this protein?
Monogalactosyldiacylglycerol synthase 1, chloroplastic, AtMGD1, MGDG synthase type A, Protein EMBRYO DEFECTIVE 2797.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane.
Protein: PANC_POLSJ
Sequence: MHIVHSIAELREKLAPFQRPAFVPTMGNLHDGHIALVKQAKPLGDVTVSSIFVNRLQFAPHEDFDSYPRTLDADAQRLEAAGCNVLFAPREKELYPEPQTYKIHPATDLGDILEGHFRPGFFIGVSTVVLKLFSCVYAGKPSGVAAFGKKDYQQVLVVRRMVQQFALPIEILAGETQRAADGLALSSRNSYLSPNERIEAAQLSKALKALGDAARATPTPDLLALEAQAMQALARRGWKPDYLTVRRRADLQPPQGPLASEPLVVLGAAKLGNTRLIDNLEI
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNC_FRATF
Sequence: MVPEYSRFYNILGYNFKDYTLLIRALTHRSKTKKNYERLEFLGDSVLSFVIAEVLYKQFTDLAEGKLSQLRSKLVKGTTLAQLASSLKMDEYIILGASEQGGNKREKILEDVFEAVIGAIYLDSDFATVKKVILKWYQPIISSINLDTIKVKDSKSKLQEILLQNALSLPEYSIETIDGKDHEQQFTVVAVSKDLNLRVKAQGTSRKKAEQKTAEKMIEMLSQQGLHEKK
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FPG_SALHS
Sequence: MPELPEVETSRRGIEPHLVGATILHAHIRNGRLRWPVSDEIYRLSDTPVLSVQRRAKYLLLELPDGWIIIHLGMSGSLRILPEALPAEKHDHVDLVMSNGKILRYTDPRRFGAWLWTKELEGHNVLAHLGPEPLSDEFNGEYLQQKCAKKKTAIKPWLMDNKLVVGVGNIYASESLFAAGIHPDRLASSLSTEECDLLARVIKAVLLRSIEQGGTTLKDFLQSDGKPGYFAQELQVYGRKGEPCRVCGTPIVATKHAQRATFYCRHCQK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: NHAA2_STRCO
Sequence: MIIGVVSGQEPEEATPSLSARSTVRWRTFVRTETSSAVFLLAAVAAALVWANVGPHSYEAVWQARFTVGFDTRRLSLTVHEWINSGLMSLFFFVVGLEARRDFDMGELRDRRWLLLSAIAGLGSMIVPALIFVLVNAGRESVHGWGTAMSTDTAFALGVLAVFGSRLPASLRAFLLSVSVVDDLVALLVIAVFYSDEIRLPALLVAVCALLAIALLRLAGVRGALYCAVLSVVVWVALHEAGVDPVVAGLAVGVLVAAYPAPRGDLEQASRLFRLFREQPTPELHRSAVQGLDAAISPNERLEQRFLPWVSFGIVPLFALANAGIELSGPALADAFTSPVTLGIVLGCVVGKVIGTVGSMAAARLLSGGRLRPNVGWGSVTVGGAIAGSAFTVSLLIASLAFDGAELEEARIGILVTLVGAFLTSWAVTAVIGLLPERRRARALLGDVDPLTDLAVPVDRRHDRIRGPESAVVTVVEYGDFECPYCGQAEPVVRDLLGQESDVRYVWRHLPLRDVHPRAQLAAEASEAAARQDRFWEMHDLLLERQNALAAPDLLRYAGELGLDVERFRQDLRDHLGARRVAEDVDSADLSRVSGTPTFFINGRRHHGAYDIAALTRAVELARQRALTG
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA 2, Sodium/proton antiporter NhaA 2.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATG12_CHAGB
Sequence: MGGAAQNNNLSNNNNDSPPASPVLEGRDSPDLPLTMAASTILTALPRDATAALAAAGGFPQEKVVVRFRPVGSAPAIRRDLVKVISTHKFDSVVAYLRKMLKVPETDGVFLYINNTFAPALDEVVGNLWRCFKDSSDHLIVSYSMSPAFG
What is the function of this protein?
Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.  Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function.  The ATG12-ATG5 conjugate functions as an E3-like enzyme which is required for lipidation of ATG8 and ATG8 association to the vesicle membranes (By similarity).
What are the official names of this protein?
Ubiquitin-like protein ATG12, Autophagy-related protein 12.
What is the protein family that this protein belongs to?
Belongs to the ATG12 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: TRMB_GEOSW
Sequence: MRLRNKPWAKEKIAAYPQYVIPNPEEHKGRWNELFGNDHPIHIEIGTGKGKFITEMAKANPNINYIGIELYPSVLVSALDKLIENELPNLRLLNVNAKDLTNFFAEGEIERIYLNFSDPWPKKRHEKRRLTYRAFLELYEKVLVDEGEIHFKTDNQAFFEYSLVSFSQYGLVLTYVSLDLHNSDFEGNVMTEYEEKFSAKGNRIYRCEVKYPPKHQKAGL
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: SP9_MOUSE
Sequence: MATSILGEEPRFGTTPLAMLAATCNKIGNTSPLTTLPESSAFAKGGFHPWKRSSSSCNLGSSLSGFAVATGGRGSGSLAGGSGAANSAFCLASTSPTSSAFSSDYGGLFSNSAAAAAAAAGVSPQEAGGQSAFISKVHTTAADGLYPRVGMAHPYESWYKSGFHSTLAAGEVTNGAASSWWDVHSSPGSWLEVQNPAGGLQSSLHSGAPQASLHSQLGTYNPDFSSLTHSAFSSTGLGSSAAAASHLLSTSQHLLAQDGFKPVLPSYSDSSAAVAAAAASAMISGAAAAAAGGSSARSARRYSGRATCDCPNCQEAERLGPAGASLRRKGLHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLSKHIKTHNGGGGGKKGSDSDTDASNLETPRSESPDLILHDSGVSAARAAAAAAAAAAAAAAAASAGGKEAATGPNDS
What is the function of this protein?
Transcription factor which plays a key role in limb development.  Positively regulates FGF8 expression in the apical ectodermal ridge (AER) and contributes to limb outgrowth in embryos.
What are the official names of this protein?
Transcription factor Sp9.
What is the protein family that this protein belongs to?
Belongs to the Sp1 C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RLMN_EXIS2
Sequence: MNKPSIYGLTLEQMTEWLSHQGHKPFRAKQVWDWLYRKRVTTFAEMTNVNKDCLELLDQSFAIDSMTQAVKQESADGTIKFLFKLYDGSLIETVLMRHKYGLSVCVTTQVGCNIGCSFCASGLIKKSRDLSAGEIVEQIMNVQHHLDAVGKEERVSHVVVMGIGEPFDNFDNMVDFLNVIKDHNGLAIGARHITVSTSGLADKIYKFADLKLQVNLAISLHAPNNELRTQIMKINRAIPLEKLMPAIDYYVKTTNRKITIEYILLRGVNDQKAQAIELAKLFEDKRHLTYVNLIPYNPVDEHGQYQRSTSEDISTFYDTLKKNGLNCGVRLEHGTDIDAACGQLRSKQIKKDTVAAK
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTBK1_HUMAN
Sequence: MQCLAAALKDETNMSGGGEQADILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWEKAGTDALLSTSTSTPPQQNTRQTAAMFGVVNVTPVPGDLLRENTEDVLQGEHLSDQENAPPILPGRPSEGLGPSPHLVPHPGGPEAEVWEETDVNRNKLRINIGKSPCVEEEQSRGMGVPSSPVRAPPDSPTTPVRSLRYRRVNSPESERLSTADGRVELPERRSRMDLPGSPSRQACSSQPAQMLSVDTGHADRQASGRMDVSASVEQEALSNAFRSVPLAEEEDFDSKEWVIIDKETELKDFPPGAEPSTSGTTDEEPEELRPLPEEGEERRRLGAEPTVRPRGRSMQALAEEDLQHLPPQPLPPQLSQGDGRSETSQPPTPGSPSHSPLHSGPRPRRRESDPTGPQRQVFSVAPPFEVNGLPRAVPLSLPYQDFKRDLSDYRERARLLNRVRRVGFSHMLLTTPQVPLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGPRSGSSSEGSERSTDRSQEGAPSTLLADDQKESRGRASMADGDLEPEEGSKTLVLVSPGDMKKSPVTAELAPDPDLGTLAALTPQHERPQPTGSQLDVSEPGTLSSVLKSEPKPPGPGAGLGAGTVTTGVGGVAVTSSPFTKVERTFVHIAEKTHLNVMSSGGQALRSEEFSAGGELGLELASDGGAVEEGARAPLENGLALSGLNGAEIEGSALSGAPRETPSEMATNSLPNGPALADGPAPVSPLEPSPEKVATISPRRHAMPGSRPRSRIPVLLSEEDTGSEPSGSLSAKERWSKRARPQQDLARLVMEKRQGRLLLRLASGASSSSSEEQRRASETLSGTGSEEDTPASEPAAALPRKSGRAAATRSRIPRPIGLRMPMPVAAQQPASRSHGAAPALDTAITSRLQLQTPPGSATAADLRPKQPPGRGLGPGRAQAGARPPAPRSPRLPASTSAARNASASPRSQSLSRRESPSPSHQARPGVPPPRGVPPARAQPDGTPSPGGSKKGPRGKLQAQRATTKGRAGGAEGRAGAR
What is the function of this protein?
Serine/threonine kinase which is able to phosphorylate TAU on serine, threonine and tyrosine residues.  Induces aggregation of TAU.
What are the official names of this protein?
Tau-tubulin kinase 1, Brain-derived tau kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPH_SALCH
Sequence: MRPAGRSANQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTASIEEGVPRFLKGQGQGWITAEYGMLPRATHTRNAREAAKGKQGGRTMEIQRLIARALRAAVDLKTLGEFTITLDCDVVQADGGTRTASITGACVALADALNKLVANGKLKTNPMKGMVAAVSVGIVNGEAICDLEYVEDSAAETDMNVVMTEDGRIIEVQGTAEGEPFSHEELLTLLALARGGIESIVATQKAALEN
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: ACYP_ALCBS
Sequence: MTTKHVLVSGIVQGVGYRAWARQEATRRNLTGWVRNCADGRVEALLEGEADAVDDMLNAMHQGPALAQVDRILVEEGNNDDDGPRSTHFEVT
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: PXPA_ECOBW
Sequence: MKIDLNADLGEGCASDAELLTLVSSANIACGFHAGDAQIMQACVREAIKNGVAIGAHPSFPDRENFGRSAMQLPPETVYAQTLYQIGALATIARAQGGVMRHVKPHGMLYNQAAKEAQLADAIARAVYACDPALILVGLAGSELIRAGKQYGLTTREEVFADRGYQADGSLVPRSQSGALIENEEQALAQTLEMVQHGRVKSITGEWATVAAQTVCLHGDGEHALAFARRLRSAFAEKGIVVAA
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: RS14Z_DESVV
Sequence: MSRTSLEVKAQRKPKFSARAYNRCPICGRPRAYLRKFGLCRICFRNMALRGELPGVRKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: PGK_FRATO
Sequence: MSFLTLKDVDLKDKKVLVRVDFNVPVKDGKVTSKVRIEAAIPTIQYILDQGGAVILMSHLGRPTEGEYDSQFSLEPVAKALSEIINKPVKFAKDWLDGVDVKAGEIVMCENVRFNIGEKKSTDDLSKKIASLGDVFVMDAFATAHRAQASTYGVAKYIPVACAGILLTNEIQALEKALKSPKKPMAAIVGGSKVSTKLSVLNNLLDKVEILIVGGGIANTFIKAEGFDVGNSLYEQDLVAEATEILAKAKALGVNIPVPVDVRVAKEFSENAQAIIKKVSYVVADEMILDIGPESQKIIAELLKSANTILWNGPVGVFEFDNFAEGTKALSLAIAQSHAFSVAGGGDTIAAIEKFGIKDQVSYISTAGGAFLEFLEGKKLPAIEILKEKAIR
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_CAMJR
Sequence: MERIRLKLKAYDHRVLDRTVAAIVEAVKRTGADIRGPIPMPTKIKRYTVLKSPHINKDSREQFEIRIHARMLDIVAATPDTVDSLTKLDLAPEVSVEVRAMGK
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: R3GEF_RAT
Sequence: MWSGPPQQDEGLPVGLSAISVPWKNLGPSKGNRKSPGGLVEASASWEEAGGEEHPAAAPLDVSRLRSSSMEIREKGSEFLKEELYKAQKELKLKDEECERLCKVRAQLEQELEELTASLFEEAHKMVREANMKQAASEKQLKEAWGKIDMLQAEVTALKTLVITSTPASPNRELHPQLLSPTKAGPRKGHSRQKSTSSLCPVVCPTAGHIPTPDKEGKEVDTTLFAEFQAWRASPTLDKNCPFLERVYREDVGPCLDFTVQELSALVRTAVEDNTLTIEPVASQTLPNVECNNTNTCALSGLARTCHHRIRLGDSDGHYYISPSSRARITAVCNFFTYVRYIQQGLVRQDAEPMFWEIMRLRKGMSLAKLGFFPQEA
What is the function of this protein?
Guanine nucleotide exchange factor (GEF) which may activate RAB3A, a GTPase that regulates synaptic vesicle exocytosis.  Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.  May also activate RAB8A and RAB8B (By similarity).
What are the official names of this protein?
Guanine nucleotide exchange factor for Rab-3A, Rab-3A-interacting-like protein 1, Rab3A-interacting-like protein 1, Rabin3-like 1.
What is the protein family that this protein belongs to?
Belongs to the SEC2 family.
Protein: TRX2_HHV6Z
Sequence: METVYCTFDHKLSLSDISTLCKLMNIVIPIPAHHHLIGSGNLGLYPIVSSNKDYVHIRNVLRTMVVTILQKVEGNQLVLRKPMTGQQYAIKNTGPFPWEKGDTLTLIPPLSTHSEEKLLKLGDWELTVPLVVPTAIAAEINIRLLCIGLIAVHREYNEMQTIIDELCSIQYRDVLIKLPDIVNDKQSMYSMKTACISLSMITAMAPDIVRTYIDRLTLEDHSMLLIKCQELLSKRTTLSTQRCGQLHATDIKDELKKIKSVLTMIDQINSLTNEKTYFVVCDVSADNRMATCIYKN
What is the function of this protein?
Structural component of the T=16 icosahedral capsid.  The capsid is composed of pentamers and hexamers of major capsid protein/MCP, which are linked together by heterotrimers called triplexes.  These triplexes are formed by a single molecule of triplex protein 1/TRX1 and two copies of triplex protein 2/TRX2.  Additionally, TRX1 is required for efficient transport of TRX2 to the nucleus, which is the site of capsid assembly.
What are the official names of this protein?
Triplex capsid protein 2.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae TRX2 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.