PharMolix/UniProtQA huggingface dataset:
Protein: LSPA_RICFE
Sequence: MFLLLKKLYITFARSSRIIITLVIIDQLSKWWFIDDLRWKPGLMLKVTSFLNMVYTWNYGISFGLMREYYQYSNAIFLITNTLIVCYLYYLMIRSKTIGSFAGYSFVIGGAVGNLIDRFFRGAVFDFIHFHYQNYSFPVFNLADCFITIGVIILIEDYYSTKKVIEEKAKGNYDNAQIEAMAEKIRNAGHNGDDIVN
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL22_DESVM
Sequence: MESRATAKFMRVSPRKARLVAQNVNGLPVEDAMNILKFTPNKPADIIFGVLRSALANAEQLPGIDVDAMVVKQIVINEGPTWKRFLPRAQGRATKIRKRTSHITVILAEGQE
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: UBA3_RAT
Sequence: MADGEEPEKKRRRIEELLAEKMAVDGGCGDTGDWEGRWNHVKKFLERSGPFTHPDFEPSTESLQFLLDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDVGRPKAEVAAEFLNDRVPNCNVVPHFNKIQDFNDTFYRQFHIIVCGLDSIIARRWINGMLISLLNYEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQVNFPMCTIASMPRLPEHCIEYVRMLQWPKEQPFGDGVPLDGDDPEHIQWIFQKSVERASQYNIRGVTYRLTQGVVKRIIPAVASTNAVIAAVCATEVFKIATSAYIPLNNYLVFNDVDGLYTYTFEAERKENCPACSQLPQNIQFSPSAKLQEVLDYLTNSASLQMKSPAITATLEGKNRTLYLQSVTSIEERTRPNLSKTLKELGLVDGQELAVADVTTPQTVLFKLHFT
What is the function of this protein?
Catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme.  E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP.  E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M.  Down-regulates steroid receptor activity.  Necessary for cell cycle progression.
What are the official names of this protein?
NEDD8-activating enzyme E1 catalytic subunit, NEDD8-activating enzyme E1C, Ubiquitin-activating enzyme E1C, Ubiquitin-like modifier-activating enzyme 3, Ubiquitin-activating enzyme 3.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
Protein: Y2995_ALKMQ
Sequence: MKVIIDGDACPVKNILFNICEHHDLELILVHSIAHMSKGEQKIETIIVDNEAEAADIMIMNRTKAGDLVITADTGLAALVLGKRAFVLSPWGHFYTNDNIGSLLDRRYLNRKMMLQGGRVKGPKKRNKEDDHRFQQALESFLEKHLRNSSKQEGV
What are the official names of this protein?
UPF0178 protein Amet_2995.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: SAHH_SOLLC
Sequence: MALLVEKTTSGREYKVKDMSQADFGRLEIELAEVEMPGLMASRAEFGPSQPVKGAKITCSLHMTIQTAFLIETLTALGAEVRWCSCNIFSTQDHAAAAIARDSAAVFAWKGETLQEYWWCTERALDWGPGGGPDLIVDDGGDATLLIHEGVKAEEEFAKNGTVPDPTSTDNVEFQLVLTIIKESLKTDPLRYTKMKERLVGVSEETTTGVKKLYQMPANGSLLFLPINVNDSVTKSKFDNLYGCRHSLPDGLMRATDVMIAGKVALVAGYGDVGKGCAAAMKQAGARVIVTEIDPICALQATMEGLQVLFLEDVVSEVDIFVTTTGNKDIIMVDHMRKMKNNAIVCNIGHFDNEIDMHGLETFPGVKRITIKPQTDRWVFPDTNSGIIVLAEGRLMNLGCATGHPSFVMSCSFTNQVIAQLELWNERSSGKYEKKVYVLPKHLDEKVAALHLGKFGAKLTKLTKDQADYIYVPVEGPYKPAHYRY
What is the function of this protein?
Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, AdoHcyase, S-adenosyl-L-homocysteine hydrolase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
Protein: FPG_SHEB8
Sequence: MPELPEVEVTRQGIAPFLVEQTVVDLVIRNGSLRWPVPDIAKQIIGQVIRQVRRRAKYLLIDTDAGTSIVHLGMSGSLRILPHDTPVEKHDHIDLVLANGRILRFNDPRRFGAWLWCELPEEAHPLLAKLGPEPLTQAFNVAQLAAALAGKKKAIKLCLMDNHIVVGVGNIYANEALFAAGIHPEAEAGKIDIERLTVLVAEVKQILAHAIKQGGTTLKDFTNADGKPGYFAQKLHVYGRGGETCTSCGNLLSEIRLGQRTTVFCGICQTR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: NU6M_LATCH
Sequence: MIYFVFVVLMGLVVGLMAVASNPAPYFAALGLVFSAVVGCGFLVGYGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPESWGSWSVFLYILVYLFGFLLVGYYCYGWWYDFYWMSLDVFGEMSVLSGDVSGVPMVYSSGGFLLLVTGWVLLLALFVVLEITRGLSRGALRAV
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: CD036_MOUSE
Sequence: MAYGLPRRNTVQTILKGSCYKVQEPWDLAELTKTWYTNLTNIRLPFLGEIVFGSPMNLLASQTKQECQFPSMQSMALEKEYEAKRLTKLKCQENVCKEIQASLREKKVGLRRPLQPK
What are the official names of this protein?
Uncharacterized protein C4orf36 homolog.
Protein: FOLD1_GEOMG
Sequence: MKLLDGKKCAESLVADIARKVAGYEESGLRKPHMTVILVGEHAPSESYVKSKIKSCGNAGFEGTLLRFPDTITEAELLEKIRGINADPTTDGLIVQLPLPRHINQQHIINAIAPEKDIDGFHPTNFGRMTLGQKAFRPATAYGICKLLQFYEIPVWGKHCVVIGRSNIVGKPISIMLSNDFDIGNATVTLTHIETPRELLLDETRRADIVIVAVGIPGFVTEDMVKEGVVVIDVGINRLEDGKIVGDVDFENVKKKCSWITPVPGGVGRMTVAALMINTLMAYQNNFDLV
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD 1.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: GCH1L_UREPA
Sequence: MKKMDIKAQDILNFLTKKYDLSKAEAWDKNGLFFDEQQTINNVQIALDITDDVVNDAILNNANLIISHHPLFTNQDSNDEVNYFVNIDLIEKIKKNKISLIHLHTAFDASANGMSMQMAKRLGLLNLKQDEQNPYLVVGELKLGVSVDYISRIIKQKFLSPIIKYNNVFRLETNLKKIGIIGGSGYKFADDAFNRYQLDMLITSDLKYHNWLDAQAKKQNIIDMNHLSESIFIDVIYDELTKFYGNDANLNKSLSIIKINYI
What are the official names of this protein?
GTP cyclohydrolase 1 type 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
Protein: CEL_BOVIN
Sequence: LGASRLGPSPGCLAVASAAKLGSVYTEGGFVEGVNKKLSLFGDSIDIFKGIPFAAAPKALEKPERHPGWQGTLKAKSFKKRCLQATLTQDSTYGNEDCLYLNIWVPQGRKEVSHDLPVMIWIYGGAFLMGASQGANFLSNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDSNLPGNYGLWDQHMAIAWVKRNIEAFGGDPDNITLFGESAGGASVSLQTLSPYNKGLIKRAISQSGVGLCPWAIQQDPLFWAKRIAEKVGCPVDDTSKMAGCLKITDPRALTLAYKLPLGSTEYPKLHYLSFVPVIDGDFIPDDPVNLYANAADVDYIAGTNDMDGHLFVGMDVPAINSNKQDVTEEDFYKLVSGLTVTKGLRGANATYEVYTEPWAQDSSQETRKKTMVDLETDILFLIPTKIAVAQHKSHAKSANTYTYLFSQPSRMPIYPKWMGADHADDLQYVFGKPFATPLGYRAQDRTVSKAMIAYWTNFARTGDPNTGHSTVPANWDPYTLEDDNYLEINKQMDSNSMKLHLRTNYLQFWTQTYQALPTVTSAGASLLPPEDNSQASPVPPADNSGAPTEPSAGDSEVAQMPVVIGF
What is the function of this protein?
Catalyzes the hydrolysis of a wide range of substrates including cholesteryl esters, phospholipids, lysophospholipids, di- and tri-acylglycerols, and fatty acid esters of hydroxy fatty acids (FAHFA) (PubMed:10220579).  Preferentially hydrolyzes FAHFAs with the ester bond further away from the carboxylate.  Unsaturated FAHFAs are hydrolyzed more quickly than saturated FAHFAs (By similarity).  Has an essential role in the complete digestion of dietary lipids and their intestinal absorption, along with the absorption of fat-soluble vitamins (By similarity).
What are the official names of this protein?
Bile salt-activated lipase, BAL, Bile salt-stimulated lipase, BSSL, Carboxyl ester lipase, Cholesterol esterase, Pancreatic lysophospholipase, Sterol esterase.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: CYB_MIRCO
Sequence: MTNIRKMHPLMKIMNSSFIDLPAPSNISSWWNFGSLLGACLAIQIITGLFLAMHYTADTATAFSSVTHICRDVNQGWIIRYIHANGASMFFMCLFIHVGRGMYYGSFTLSETWNIGIILLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTSLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVMVHLLFLHETGSNNPLGTTSDSDKIPFHPYYTIKDLLGLLFLLLLLMMLVLFSPDLLGDPDNYTPANPLITPPHIKPEWYFLFAYAILRSIPNKLGGVLALIMSILILAILPLLQTTKQRSMVFRPFSQIMFWTLTADLFTLTWIGGQPVEYAFVIIGQIASILYFSLILIIMPTVSLIENNMLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL1_THESQ
Sequence: MPKHSKRYLEARKLVDRTKYYDLDEAIELVKKTATAKFDETIELHIQTGIDYRKPEQHIRGTIVLPHGTGKEVKVLVFAKGEKAKEALEAGADYVGAEDLVEKIEKEGFLDFDVAIATPDMMRIIGRLGKILGPRGLMPSPKSGTVTQEVAEAVKEFKKGRIEVRTDKTGNIHIPVGKRSFDNEKLKENIIAAIKQIMQMKPAGVKGQFIKKAVLSSTMGPGIKLNLQSLLKE
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: MTND_EXIS2
Sequence: MATVLFQKTNERYTDQNEVSAFLASRGVLYEQWDVSKLPAELVDTYTLTDADKQTILDTFQSEITDVSERRGYQTADIISLSDATPNLDELLVNFQKEHHHTDDEVRFIVSGHGVFAIQDDEVGYYNIELNPGDLISVPVNTRHYFTLQEDRKVVAVRIFVTTDGWVPIYEKDPIETAN
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, DHK-MTPene dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
Protein: P2C49_ORYSJ
Sequence: MAAEICREEAAKSMPAAAAGATAIARRRRRVEGFRFAAGSLEPPQEDADAGVARCGKRQRVAGARAGAGAATAGPCRPSAGAEFGSRWWPRYGVTSVFGRRREMEDAVSIRPDFLRGSTSSGKHHFFGVFDGHGCSHVARMCQDRMHELVVDAYKKAVSGKEAAAAAPAWKDVMEKGFARMDDEATIWAKSRTGGEPACRCELQTPARCDHVGSTAVVAVVGPNRVVVANSGDSRAVLCRAGVPVPLSVDHKPDRPDELERIKAAGGRVIYWDGARVLGVLAMSRAIGDGYLKPYVTSEPEVTVTERADDDECLILASDGLWDVVTNEMACEVVRACFRSNGPPSPPGCSRPKAVLPPPAGASGGGGGDAVVKGVDKAESDKACADAALLLAKLAIARRSADNVSVVVVDLRRPVP
What are the official names of this protein?
Probable protein phosphatase 2C 49, OsPP2C49.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: CF1A_DROME
Sequence: MAATSYMTPPSGDLDMALGGGGYHTSSPRSAADAGEMKYMQHHHHHHAAAAAAAHHQLPSSPSPNGQGNGGGLGLGSGSGLGSWSALHPDPWMQTHHTHHLPAAAAVASAADTVKQEMSHLSQQTRIQQGMASPHAAWHAPHAGHYAPTGGSPLQYHHAMNGMLHHPAHAVAAAHHQSVAPLHHTLRGESPQLHIHHHMGGGDRDAISGGEEDTPTSDDLEAFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLQKWLEEADSTTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALEQHFHKQPKPSAQEITSLADSLQLEKEVVRVWFCNRRQKEKRMTPPNTLGGDMMDGMPPGHMHHGGYHPHHDMHGSPMGTHSHSHSPPMLSPQNMQSSAVAAHQLAAH
What is the function of this protein?
Binds to a DNA sequence element required for the expression of the dopa decarboxylase gene (Ddc) in specific dopaminergic neurons.  Could also play an early role in specific ectodermal cells, and a subsequent role in the embryonic nervous system.
What are the official names of this protein?
POU domain protein CF1A, Chorion factor 1A, CF1-A, Protein drifter, Ventral veins lacking protein.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL32_NITHX
Sequence: MAVPRRKTSPSRRGMRRSADAISKPTYAEDKDSGELRRPHHLDLKTGMYKGRQVLKAKSES
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: HSLV_RICCN
Sequence: MSDNLSLHGTTILCLKKNEEIIIAADGQVSHGNTVLKSTARKLRTIANNKIIAGFAGSTADGLALFEKLAVKIEQHKHNLLRSAVELAKDWRSDKYLRRLEAMMIVADRSHILILTGNGDVVEPENNVAAIGSGGLFALSAARALMSYENNLTAEEIALKSMNIAADLCVFSNHNIIMEKVV
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANC_SHIFL
Sequence: MLIIETLPLLRQQIRRLRMEGKRVALVPTMGNLHNGHMKLVDEAKARADVVVVSIFVNPMQFDRPEDLARYPRTLQEDCEKLNKRKVDLVFAPSVKEIYPNGTETHTYVDVPGLSTMLEGASRPGHFRGVSTIVSKLFNLVQPDIACFGEKDFQQLALIRKMVADMGFDIEIVGVPIMRAKDGLALSSRNGYLTAEQRKIAPGLYKVLSSIADKLQAGERDLDEIITIAGQELNEKGFRADDIQIRDADTLLEVSETSKRAVILVAAWLGDARLIDNKMVELA
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPEE_HELPS
Sequence: MWITQEITPYLRKEYTIEAKLLDVRSEHNILEIFKSKDFGEIAMLNRQLLFKNFLHIESELLAHMGGCTKKELKEVLIVDGFDLELAHQLFKYDTHIDFVQADEKILDSFISFFPHFHEVKNNKNFTHAKQLLDLDIKKYDLILCLQEPDIHKMDGLKRMLKEDGVFISVAKHPLLEHVSMQNALKNMGEFFSVAMPFVAPLRILSNKGYIYASFKTHPLKDLMAPKIEALKSVRYYNEDIHRAAFALPKNLQEVFKDNIKS
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXY_RUBXD
Sequence: MSQGGGLNILSIQSSVAYGHVGNSAAVFPLQRLGIEVWAVNTVHFSNHTGYGEWRGPVLAAGDVSEVLRGIGERGVLGSCGAVLSGYMGDVSLGEVILGAVGRVRGANPQALFCCDPVMGDEGRGFFVRPGIPRFMRERAVPAADVVTPNQFELEYLAGVEVRTLGGALAAAEKVLGLGPGTVLVTSLRRRDAGEEGRIEMLAATREGAWLVGTPLLPLEVNGAGDATAALFLGHLLLGRGLEEALSLTASSVYAVLEKTLRRGAREIQLVAAQESLVAPPVRFPVRRVA
What is the function of this protein?
Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP).  Catalyzes the phosphorylation of pyridoxal to PLP.
What are the official names of this protein?
Pyridoxal kinase PdxY, PL kinase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxine kinase family. PdxY subfamily.
Protein: MTU1_YEAST
Sequence: MLARYLNLIGRRSASPYRPQRLPAKFDNVIVAMSSGVDSSVAAALFAGEFPNTRGVYMQNWSESQSLDDPGKEPCYERDWRDVNRVAKHLNIRVDKVNFEQDYWIDVFEPMLRGYSEGSTPNPDIGCNKFVKFGKLREWLDEKYGTGNYWLVTGHYARVMQEMNGKGLFHLLRSIYRPKDQSYYLSQINSTVLSSLLLPIGHLTKPEVRDLAKYAGLPTAEKPDSQGICFVNNSQHGKFKNFLKHYLPSSPGDIITVDPQSGAKTTWGRHDGLWSYTIGQKVGISMPQADPNYQGTWFVSEKLRDTNEILIVRGRDNPALYSDTMRIENFSSLGPREDTINAFQNTGALTLQFRSLQVPVQIKSCKLNRSADNLDITIHLASKQRAITPGQSCCLYIDDRVLGSGPISHVNNNDTHA
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position.  ATP is required to activate the C2 atom of the wobble base.
What are the official names of this protein?
Mitochondrial tRNA-specific 2-thiouridylase 1, Mitochondrial translation optimization protein 2, Synthetic lethal with MSS4 3.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ASSY_SHIB3
Sequence: MTTILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEEDYDAIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNTTPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDTDFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEYLNSSVKIVNPIMGVKFWDESVKIPAEEVTVRFEQGHPVALNGKTFSNDVEMMLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHAHGRQLGRLLYQGRWFDSQALMLRDSLQRWVASQITGEVTLELRRGNDYSILNTVSENLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFGYAKTGLLSSSATSGVPQVENMENKGQ
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAI_PINKO
Sequence: MIIPNLPFNLPFNLPFNLPFNLPSILPSILVPLVGLLLPAITMVLSHLYIQNDEIL
What is the function of this protein?
May help in the organization of the PsaL subunit.
What are the official names of this protein?
Photosystem I reaction center subunit VIII, PSI-I.
What is the protein family that this protein belongs to?
Belongs to the PsaI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: SOCS2_HUMAN
Sequence: MTLRCLEPSGNGGEGTRSQWGTAGSAEEPSPQAARLAKALRELGQTGWYWGSMTVNEAKEKLKEAPEGTFLIRDSSHSDYLLTISVKTSAGPTNLRIEYQDGKFRLDSIICVKSKLKQFDSVVHLIDYYVQMCKDKRTGPEAPRNGTVHLYLTKPLYTSAPSLQHLCRLTINKCTGAIWGLPLPTRLKDYLEEYKFQV
What is the function of this protein?
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction.  SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway.  Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
Suppressor of cytokine signaling 2, SOCS-2, Cytokine-inducible SH2 protein 2, CIS-2, STAT-induced STAT inhibitor 2, SSI-2.
Protein: APAG_SHESR
Sequence: MSALDDSIRVEVKTEYIEQQSSPEDQKYLFSYTITIVNLGEQAAKLETRHWIITDANGKITEVQGAGVVGETPTIPPNTAYQYTSGTVLDTPLGIMYGTYGMVSESGERFKATIKPFRLALPGLLH
What are the official names of this protein?
Protein ApaG.
Protein: CH60_SODGL
Sequence: MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPVITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQSIVNEGLKAVAAGMNPMDLKRGIDKAVIAAVEELKKLSVPCSDSKAIAQVGTISANADETVGTLIAEAMAKVGKEGVITVEEGSGLQDELDVVEGMQFDRGYLSPYFVNKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKIAAVKAPGFGDRRKAMLRDIAILTAGTVISEEIGLELEKATLEDMGQAKRVVITKDTTTIIDGEGDKALIDSRVTQINQQRDEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVANRIAELRGDNEDQNVGIKVARRAMEAPLRQIVANAGEEPSVIANKVKAGEGNTGYNAATEEYGNMIDMGILDPTKVTRSALQYAASIAGLMITTECMVTDLPKEDKPDLGGAGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_LEPBL
Sequence: MYGQVERKRVNFGKITNLDYLPNLIQIQKRSFDWFLQADVKDETKRKHQGLEAVFRETFPIESPNNDMIMEYSHYILGEPKRSPQECKDTDATFAMPLKAVIRLIIKETGEIREQTVYMGDLPVMTEQGTFIINGAERVVVSQLHRSPGIFFSYDMERDVFSARVIPYRGSWLEFEMDNKGILIAKIDRKKKFPATLLIKSLGHGTNEEVLRLFYSSKKEKIAGATSKDLKKILGRRTINDIINMETGEVMLEAGSKVNEDNISILKEMKVKEVELIEFPKGKDNPILINALEKDGVNDYEDAILKFHSLMRQGEPSTIENATTELTRLFFSPKTFDLGEVGRYKINSKFEFNNPKEFSGEKARVLRPADIIETVRYILNLFSETENYYPDDIDHLGNRRIRSVGELISNQLKTGFSRVERVIKERMTVQEIETQTPQLLISIKPITAVINEFFGSSQLSQFMDQTNPLAELTHKRRLNALGPGGLSRDRAGMEVRDVHYSHYGRMCPIETPEGPNIGLILSMSSYARVNDYGFLETPYRTVKNGKVTGQIEHLTADKEEYHYIAQASGVIDEKGELKNKLISTRHRGDFPFRNPSEIQYMDLAPLQVVSVSTALIPFLEHDDANRALMGSNMQRQAVPLLREEAPFVGTGMETRAAYDSRICIVNKHDGVVTSVDAETIVVERKGGKESDTYSLTKFKKTNQGTCFNQKPIVGVVHSEINGKVSKVSKEKIEVTGENGELKEYVLQIGSKQYAPIVSSGEEVKRGTTLAGQVVVGEKLDEMGNILVKGTVLADGPAVDNGVLALGRNVLAAFMPWEGYNFEDAILISERIVRDDVFSSIHIEEFEIQARETKLGPEQITRDIPNLSDKAFRDLDETGVIRIGAEVKPGDILVGMVTPKGETDLTPEYKLLHSIFGEKAKDVRDSSLRMPNGFEGTVIDIKRFSRENQDELPAGVEEMVKVFVARKRKLLVGDKMAGRHGNKGVVARVMAEEDMPYMEDGTPLDIVLNPLGVPSRMNLGQIFETQLGFAASKLGISFETPVFDGAEESDVDNFCKEANLPLNSKFKLYDGRTGLPFMNEVFCGYIYILKLAHLVEDKIHARSTGPYSLVTQQPLGGKAQFGGQRLGEMEVWALEAYGASHTLQELLTIKSDDMLGRARIYEAIVKGIHSIKPGIPESFNVLVQELRGLALDIIITDSEGNTVDISDYEDEYSKSKKKIKFETIENA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: URED1_BRUA4
Sequence: MIINNNKLAELSSQRVNGLGGLSIHFKDGRSRISRLYQEGAAKIRMPQVGGDPLEAILINTSGGLTGGDRLQWDVELGENASAVITTQACERIYRSGGGEARIATRLKAAKGTRLAWLPQETILFNQSVLSRTLDVELEEGAEILVVEATIFGRLAMGERVDEAMFSDRWRVRLGGRPDGRLVHAEEFRLGPDIGAELQARPVADAACAVATVLLISGEAGKHLEAARQIIGEEGGASLWQVGPATKLMMRLHAPDSYTLRKRLGPLLALLNGKAGLPKVWTF
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD 1.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLUE_PSEAE
Sequence: MAKAPPSEPKLLLFNKPFDVLTQFNDEQGRSTLKDFIPVPGVYPAGRLDRDSEGLLLLTNDGRLQARIADPRHKLPKTYWVQVEGTPDEEQLRRLREGVTLNDGPTLPAEARLLDEPTLWERVPPVRFRKSVPTHWLELVIREGRNRQVRRMTAAVGLPTLRLVRVRIGPWSLDGLGLGEWREVPARLD
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-2457 in 23S ribosomal RNA.
What are the official names of this protein?
Ribosomal large subunit pseudouridine synthase E, rRNA pseudouridylate synthase E, rRNA-uridine isomerase E.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RsuA family.