PharMolix/UniProtQA huggingface dataset:
Protein: TMCAL_LISMH
Sequence: MKATGIVVEYNPFHNGHKLHLNKARELTQADVVIAVMSGSFVQRGEPAIIPKWERAKMALAAGVDMVIELPVSFATQHATIFAEEAVRILDAIHVDTLFFGSEHGVAEDFTFAAKKVVENEARFDEAIQLALVDKKTSYARAYTEAFKKLFGQNLLDITKPNNILGFHYALAAQNQNPSISLQTIPREHAGYHDEEANHDQIASATAIRKLILAGKLEEASHYLPASSIAILRNYEGPFLSWKDYWSFLQYRLIQAGSEELEGIRGVSEGIQNRMQQAATKAQNFSDFIELTKTKRYSNTRLQRTALQILLNARSQTSSPYIRILGMNKTGQQYLSLHKKNISLPIVTTVSKAPVGLLEEELRATNIYTLAKGLENYQAGDFHIPPILTL
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_ECO24
Sequence: MATNAKPVYKRILLKLSGEALQGTEGFGIDASILDRMAQEIKELVELGIQVGVVIGGGNLFRGAGLAKAGMNRVVGDHMGMLATVMNGLAMRDALHRAYVNARLMSAIPLNGVCDSYSWAEAISLLRNNRVVILSAGTGNPFFTTDSAACLRGIEIEADVVLKATKVDGVFTADPAKDPTATMYEQLTYSEVLEKELKVMDLAAFTLARDHKLPIRVFNMNKPGALRRVVMGEKEGTLITE
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LHTL6_ARATH
Sequence: MVSSSPVSPSKETDRKSGEKWTAEDPSRPAKWWYSTFHTVTAMIGAGVLSLPYAMAYLGWGPGTFVLAMTWGLTLNTMWQMVQLHECVPGTRFDRYIDLGRYAFGPKLGPWIVLPQQLIVQVGCNIVYMVTGGKCLKQFVEITCSTCTPVRQSYWILGFGGVHFILSQLPNFNSVAGVSLAAAVMSLCYSTIAWGGSIAHGRVPDVSYDYKATNPGDFTFRVFNALGQISFAFAGHAVALEIQATMPSTPERPSKVPMWQGVIGAYVVNAVCYFPVALICYWAFGQDVDDNVLMNLQRPAWLIAAANLMVVVHVIGSYQVFAMPVFDLLERMMVNKFGFKHGVVLRFFTRTIYVAFTLFIGVSFPFFGDLLGFFGGFGFAPTSFFLPSIMWLIIKKPRRFSVTWFVNWISIIVGVFIMLASTIGGLRNIIADSSTYSFYA
What is the function of this protein?
Amino acid transporter.
What are the official names of this protein?
Lysine histidine transporter-like 6.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family. Amino acid/auxin permease (AAAP) (TC 2.A.18.2) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS27_THEGJ
Sequence: MALPKNLIPMPRSRFLRVKCIDCGNEQIVFSHPATKVRCLVCGATLVEPTGGKGVIKAKILEVLE
What are the official names of this protein?
30S ribosomal protein S27e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS27 family.
Protein: Y979_BURP6
Sequence: MQYEIVSAGEDVDDERARGRRAAAPAAPSSAVPSSAALSSAALSSAARPTGAPPATAAARRGRDLPRERLLARGPAALSDAELVALLLGSGLPGHDVFALAHTLLARFGSLRALLDAAPDDFKGLRGIGPARTAILVAVVELARRALAEKARERPLVDSPGAVDDYLRLLIGTRPREVFVCLFLDARHRLVQTEETAHGSLTRMAVYPREIVRRALALNAAALIVAHNHPSGAVRPSAADRRLTRVLRDALALVDIKLIDHFVVGASDTFSFAQAGWI
What are the official names of this protein?
UPF0758 protein BURPS668_0979.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: MCPH1_HYLLA
Sequence: MAAHILKDVVAYVEVWSSNGTENYSKTFTTQLVDMGAKVSKTFNKQVTHVIFKDGYQSTWDKAQKRGVKLVSVLWVEKCRTAGAHIDESLFPAINTNEHLPSLIKKKRKCMQPKDFNFKTPENDKRFQKKFEKMAKELQRQKTSLDDDVPILLFESSGSLTYSPTIKINSSHHSAMEKRLQEMKEKRENLSPSSSQMIQQSHDNPSNSLCEAPLNISRDTLCSDESFAGGVHSSFDDLCGNSGCGNQERKLGGSINDIESDMCISSLVLKANNIHSSPSFTHLDKSSPQKFLSNLSKEEINLQRNIAGKIVTPDQKQAAGMSQETFEEKYRLSPTLSSTKGHLLIRSRPSSSSVKRQRVSHGSHSPSKGKSKRKRSIRRSIMPRLQLCRSEGSLQHVAGPALKALSCGESSYDDYFSPDNLKERNSENLPPTSQLPSSLAQFSCRSLSKKERTSIFEMSDFSCIGKKTRTVDITSFTAKTISSPQKTANGEGRATLSCVTSEESSAPGETLRCCRQAGKEDACPEGNGFSYTIEDPPFPKGHDGDLTPLEGSLEEVKEAVGLKSTQNKGTTSKISNSSEGEAQSEHEPCFIVDCNMETSTEEKENLPGGYGGSVKNRPTRHDLLDDSCDSFKDLIKPHEELKKSGRGKKPTRTLVMTSMPSEKQNVVIQVVDKLKGFSIAPDVCETTTHVLSGKPLRTLNVLLGIARGCWVLSYDWVLWSLELGHWISEEPFELSNHFPAAPLCRSECHLSAGPYRGTLFADQPVMFVSPASSPPVAKLCELVHLCGGRVSQVPRQASIVIGPYSGKKKATVKYLSEKWVLDSIIQHKVCASENYLLPQR
What is the function of this protein?
Implicated in chromosome condensation and DNA damage induced cellular responses.  May play a role in neurogenesis and regulation of the size of the cerebral cortex (By similarity).
What are the official names of this protein?
Microcephalin.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: RL17_STRP2
Sequence: MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTVEKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAERNGGYTRILKTEPRRGDAAPMAIIELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: ALDH_STAA3
Sequence: MRDYTKQYINGEWVESNSNETIEVINPATEEVIGKVAKGNKADVDKAVEAADDVYLEFRHTSVKERQALLDKIVKEYENRKDDIVQAITDELGAPLSLSERVHYQMGLNHFVAARDALDNYEFEERRGDDLVVKEAIGVSGLITPWNFPTNQTSLKLAAAFAAGSPVVLKPSEETPFAAVILAEIFDKVGVPKGVFNLVNGDGAGVGNPLSEHPKVRMMSFTGSGPTGSKIMEKAAKDFKKVSLELGGKSPYIVLDDVDIKEAAKATTGKVVNNTGQVCTAGTRVLVPNKIKDAFLAELKEQFSQVRVGNPREDGTQVGPIISKKQFDQVQNYINKGIEEGAELFYGGPGKPEGLEKGYFARPTIFINVDNQMTIAQEEIFGPVMSVITYNDLDEAIQIANDTKYGLAGYVIGKDKETLHKVARSIEAGTVEINEAGRKPDLPFGGYKQSGLGREWGDYGIEEFLEVKSIAGYFK
What are the official names of this protein?
Putative aldehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: RPOA_ELYHY
Sequence: MVREEVAGSTQTLQWKCVESRVDSKRLYYGRFILSPLRKGQADTVGIALRRALLGEIEGTCITRAKFGSVPHEYSTIAGIEESVQEILLNLKEIVLRSNLYGVRDASICVKGPRYITAQDIILPPSVEIVDTAQPIANLTEPIDFCIDLQIKRDRGYQTELRKNYQDGSYPIDAESMPVRNVNYSIFSCGNGNEKHEILFLEIWTNGSLTPKEALYEASRNLIDLFLPFLHAEEEGTSFEENKNRFTPPLFTFQKRLTNLKKNKKGIPLNCIFIDQLELTSRTYNCLKRANIHTLLDLLSKTEEDLLRIDSFRMEDRKHIWDTLEKHLPIDLLKNKLSF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SYFA_THEAC
Sequence: MHIPIPMVQISEAEYRVLRAIQSRGATAIESELSVEGLSDREIASAISWLEVKGLLDVERREIKTYALSSEGKRYLREGLPELVLYRKLKERGEMTMDEIRDLMPDTYRIALAQLAKFGITPKEGKLIYRNSGIEAAIEERQRFLQSMDPKNTAMIDHFRHRSGVIDEKIRTERIVRLNDSAYEAIAEFGGEGLIGSLDPSIIASGEWKTKNFRKYDLNSPSSVIRSSLKHPMTYLIEEIREIFLNMGFTEMGGHYIESTLWDMDSLFIPQDHPARDMQDTFYVEADSFDIDHPEISKKIRKIHEKGFDGYSGWGYRWSDAEARKLVLRTHTTVSTARYLYENNEPPQAIFSVEKVFRHESVDWKHLAEFYQIEGAVYSKDVSVSTLKWILRDFYAKLGFNDIKLIPSYYPYTEPSLDVVVRVNGKEVELGGSGLFRPEVLKILGLKAPVMAWGMGLERLAMMYYGLTDVRDLYNTDFEFLSSFRFNISRNGRNNYGKA
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_GRABC
Sequence: MNTSDHPAPAAYDVIVVGGGHAGCEAAAAAARTGAITALVTHQAATIGEMSCNPAIGGIGKGHLVREIDALDGLMGRAIDQACIHFKMLNRSKGPAVRGPRAQADRKLYKKAVQDILHTTPHLSIIEGSVEDLITSSGTQQTVQGVILQDGRHLSASAVVLTTGTFLRGVIHCGEQRSEAGRVGEAPSIGLAKRLDALNLRMGRLKTGTPPRIDRRSIAWEDLPEDRGENPPTPFSTLNHHIDLPQISCRISETTADTHQIIRDNLHRSAVYGGMLSGKGPRYCPSIEDKVVRFPDKTRHQVFLEPEGLDDFTVYPNGISTSLPAEVQEALLHSMPGLHNAVIIRPGYAVEYDFVDPRSLRPSLELKELPGLFLAGQINGTTGYEEAGAQGLMAGLNAARKAQGLDSVTLDRSQAYIGVLIDDLTTHGVTEPYRMFTSRSEFRLTLRADNADRRLTRWGRQAGCVSDERWKTFAAYDQAMNDALTLAAQDTRTPVQLQQVGITVRQDGRRRPLLSLIGSDPEQDQKLNQAFPWLHDLDPRVREQLEIEGAYSGYLSRQDKERRVLQQEDTILLSDHIDYSAIGGLSAEIRDKLQSLRPTSLGAASRMEGMTPAALAAISHFVRRKQCFT
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7L_RICCK
Sequence: MLDNFIVNQATKEFSVSEISNKIKELLENNFGYIKIKGEISGFKIASSGHAYFNLKENTAILACTCWRPTLAKIKFPLKDGMEVVISGKLSSYAGNSRYQLAVDNLQPAGLGTMLQILNERKTRLEKEGLFNKRRIPIPFLPTRIGVITSITGAVIKDIIHRIRERFPTHIIIWPVSVQGENSGNEIAAAIEGFNKLEEANKPSVIIVARGGGSIEDLWSFNDEILVRAAYNSKIPIISAVGHEVDYTLIDLAADKRAPTPTAAAEFAVPVRSILNNTLQSYEKVLLNNTKQLINYHEQNIANYDKIHRYLTNYINHRQQLLDETGFNLLDVLPCFIELQETKLKFCSKERINPAKIINYKTLELTHQTAYLSKSANNTLKNFEYKLELNSTLLASLDYHNVLKRGFAIVKGAMGNFLSSKITAADEKIFNIKFSDGEIKVVRN
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XKS1_ARTOC
Sequence: MGSSGGPLYIGFDLSTQQLKGLVVSSDLKVVHIAKFDFDSDSKGFNISKGVLTNEDEGEVFAPVAMWLQALDAVLQDLKHQGLDFSLVRGISGAGQQHGSVYWNESAEEILGGLDGGKTLEDQLQQALSYPYSPNWQDSSTQRECDEFDAFLGSEEELARVTGSKAHHILRFQRKHPDAYRKTSRISLVSSFLASIFLGSVAPFDISDVCGMNLWDMPMNRWNERLLKLCAGEAGPEELKKKLGDVPHDGGQELGKISSYFAKRYSFHPDCAITPSTGDNPATILALPLRPLDAMVSLGTSTTFLMSTPQYKPDPSTHFFNHPTTPGLYMFMLCYKNGGLAREQVRDAINATSGEKTDPSNPWSNFDRVLLETPPGGQKAGSGPMKMGLFFPRPEIVPNLGEGEWHFNYTPGQANEELKETDEGWTHPRDDARAIVESQFLSLRLRSKELVHSPSGGVPPQPRRIYLVGGGSRNAAIAKVAGEVLGGIEGVYKLDVGENACALGAAYKAVWALERAPDQTFEDLIGRRWREDEFVEKIADGFQPDIFEKYRQAVQGFEKMEKQVLMEAKQ
What is the function of this protein?
Highly specific D-xylulose kinase which participates in the catabolism of xylose.  Xylose is a major component of hemicelluloses such as xylan.  Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway (By similarity).
What are the official names of this protein?
Probable D-xylulose kinase A, Xylulokinase A.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y762_ARCFU
Sequence: MCLQIGGGGMDLRGQTFTLEGVAASLLILLAVYTIFQSTVVIAPSWSDYANVQLKQLGYDILRVFDSDGGNSSLKGAIVNCSSGFKAPDEFNANLSKILDSLNAFGKVELIWVNGSKIESHALYGFNKTPTPDAVRVSRFVVVQDLNNSECFNLTTPTTKVVEVRLTLWRT
What are the official names of this protein?
Uncharacterized protein AF_0762.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: 3L2L_LATLA
Sequence: KTLLLTLVVVTIICLDFGYTRICFKTPYVKSETCPPGQELCYTKTWCDRFCSIRGKVIELGCTATCPRAEPKEDTTCCSKDNCNPHP
What is the function of this protein?
Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission.
What are the official names of this protein?
Long neurotoxin LlLong.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Long-chain subfamily. Type II alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ISK1_SHEEP
Sequence: NILGREAKCTNEVNGCPRIYNPVCGTDGVTYANECLLCMENKERQTPVLIQKSGPC
What is the function of this protein?
In the male reproductive tract, binds to sperm heads where it modulates sperm capacitance by inhibiting calcium uptake and nitrogen oxide (NO) production.
What are the official names of this protein?
Serine protease inhibitor Kazal-type 1, Pancreatic secretory trypsin inhibitor.
What are the subcellular locations of this protein?
Secreted.
Protein: RL20_SULNB
Sequence: MRVKTGVVRHRRHKRLLKQARGFYSGRRKHFRKAKEQLERSLVYAYRDRRQKKRDFRKLWIVRINAAARLNDLNYSRFMHGLKLANIELDRKILADMAMNSPESFTKIADASKAALTK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: T23O_XENLA
Sequence: MSGCPFMAKKHHFTFSELSLEDKHEDNSQEGLNKASKGGLIYGDYLQLDKVLNAQELQSEKKGNKIHDEHLFIVTHQAYELWFKQILWELDSVREIFQNGHVRDERNMLKVVARIHRISMILKLLVEQFSVLETMTAMDFFDFRDYLSPASGFQSLQFRLLENKIGVPEILRVPYNRRHYRDNFKGETNELLLRSEQEPTLLGLVEAWLERTPGLEEEGFHFWGKLEVNIFRALEEELQAAKTKPDSEDKEEHLAELQKQKELFGALFDERRHEHLLSKGERRLSYKALKGALMINFYREEPRFQVPFQLLTSLMEIDTLMTKWRYNHVCMVHRMIGSKAGTGGSSGYQYLRSTVSDRYKVFVDLFNLSTYLVPRHWVPRLNPSIHKFLYTAECCDSSYFSSDDSD
What is the function of this protein?
Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine.  Catalyzes the oxidative cleavage of the indole moiety.
What are the official names of this protein?
Tryptophan 2,3-dioxygenase, TDO, Tryptamin 2,3-dioxygenase, Tryptophan oxygenase, TO, TRPO, Tryptophan pyrrolase, Tryptophanase.
What is the protein family that this protein belongs to?
Belongs to the tryptophan 2,3-dioxygenase family.
Protein: FIBA_RAT
Sequence: MLSLRVACLILSLASTVWTADTGTTSEFIEAGGDIRGPRIVERQPSQCKETDWPFCSDEDWNHKCPSGCRMKGLIDEANQDFTNRINKLKNSLFDFQKNNKDSNSLTRNIMEYLRGDFANANNFDNTFGQVSEDLRRRIQILKRKVIEKAQQIQVLQKDVRDQLIDMKRLEVDIDIKIRSCKGSCSRSVSREINLKDYEGQQKQLEQVIAKDLLPAKDRQYLPAIKMSPVPDLVPGSFKSQLQEGPPEWKALTEMRQMRMELERPGKDGASRGDLPGDSRGDSATRGPGSKIENPMTPGHGGSGYWRPGSSGSGSDGNWGSGTTGSDDTGTWGAGSSRPSSGSGNLKPSNPDWGEFSEFGGSSSPATRKEYHTGKLVTSKGDKELLIGNEKVTSTGTSTTRRSCSKTITKTVLGNDGHREVVKEVVTSDDGSDCGDGMDLGLTHSFSGRLDELSRMHPELGSFYDSRFGSLTSNFKEFGSKTSDSDIFTDIENPSSHVPEFSSSSKTSTVRKQVTKSYKMADEAASEAHQEGDTRTTKRGRARTMRDCDDVLQTHPSGAQNGIFSIKLPGSSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNDYLHLLTLRGSVLRVELEDWAGKEAYAEYHFRVGSEAEGYALQVSSYQGTAGDALMEGSVEEGTEYTSHSNMQFSTFDRDADQWEENCAEVYGGGWWYNSCQAANLNGIYYPGGTYDPRNNSPYEIENGVLWVPFRGADYSLWAVRMKIRPLVGQ
What is the function of this protein?
Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix.  Fibrin has a major function in hemostasis as one of the primary components of blood clots.  In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization.  Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood.  However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo.  Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway.  Maternal fibrinogen is essential for successful pregnancy.  Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage.  May also facilitate the immune response via both innate and T-cell mediated pathways.
What are the official names of this protein?
Fibrinogen alpha chain.
What are the subcellular locations of this protein?
Secreted.
Protein: TNR16_RAT
Sequence: MRRAGAACSAMDRLRLLLLLILGVSSGGAKETCSTGLYTHSGECCKACNLGEGVAQPCGANQTVCEPCLDNVTFSDVVSATEPCKPCTECLGLQSMSAPCVEADDAVCRCAYGYYQDEETGHCEACSVCEVGSGLVFSCQDKQNTVCEECPEGTYSDEANHVDPCLPCTVCEDTERQLRECTPWADAECEEIPGRWIPRSTPPEGSDSTAPSTQEPEVPPEQDLVPSTVADMVTTVMGSSQPVVTRGTTDNLIPVYCSILAAVVVGLVAYIAFKRWNSCKQNKQGANSRPVNQTPPPEGEKLHSDSGISVDSQSLHDQQTHTQTASGQALKGDGNLYSSLPLTKREEVEKLLNGDTWRHLAGELGYQPEHIDSFTHEACPVRALLASWGAQDSATLDALLAALRRIQRADIVESLCSESTATSPV
What is the function of this protein?
Low affinity receptor which can bind to NGF, BDNF, NTF3, and NTF4 (PubMed:3027580, PubMed:15131306, PubMed:18596692).  Forms a heterodimeric receptor with SORCS2 that binds the precursor forms of NGF, BDNF and NTF3 with high affinity, and has much lower affinity for mature NGF and BDNF (PubMed:24908487, PubMed:22155786).  In response to proNGF binding, the heterodimeric receptor with SORCS2 activates a signaling cascade that leads to decreased Rac activity, reorganization of the actin cytoskeleton and neuronal growth cone collapse (PubMed:22155786).  Plays an important role in differentiation and survival of specific neuronal populations during development (By similarity).  Can mediate cell survival as well as cell death of neural cells (PubMed:10514511, PubMed:10985348, PubMed:24908487).  Plays a role in the inactivation of RHOA (By similarity).  Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity).  Necessary for the circadian oscillation of the clock genes BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus (SCN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver (By similarity).
What are the official names of this protein?
Tumor necrosis factor receptor superfamily member 16, Gp80-LNGFR, Low affinity neurotrophin receptor p75NTR, Low-affinity nerve growth factor receptor, NGF receptor, p75 ICD.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Perikaryon. Cell projection, growth cone. Cell projection, dendritic spine.
Protein: RLF_HUMAN
Sequence: MADGKGDAAAVAGAGAEAPAVAGAGDGVETESMVRGHRPVSPAPGASGLRPCLWQLETELREQEVSEVSSLNYCRSFCQTLLQYASNKNASEHIVYLLEVYRLAIQSFASARPYLTTECEDVLLVLGRLVLSCFELLLSVSESELPCEVWLPFLQSLQESHDALLEFGNNNLQILVHVTKEGVWKNPVLLKILSQQPVETEEVNKLIAQEGPSFLQMRIKHLLKSNCIPQATALSKLCAESKEISNVSSFQQAYITCLCSMLPNEDAIKEIAKVDCKEVLDIICNLESEGQDNTAFVLCTTYLTQQLQTASVYCSWELTLFWSKLQRRIDPSLDTFLERCRQFGVIAKTQQHLFCLIRVIQTEAQDAGLGVSILLCVRALQLRSSEDEEMKASVCKTIACLLPEDLEVRRACQLTEFLIEPSLDGFNMLEELYLQPDQKFDEENAPVPNSLRCELLLALKAHWPFDPEFWDWKTLKRHCHQLLGQEASDSDDDLSGYEMSINDTDVLESFLSDYDEGKEDKQYRRRDLTDQHKEKRDKKPIGSSERYQRWLQYKFFCLLCKRECIEARILHHSKMHMEDGIYTCPVCIKKFKRKEMFVPHVMEHVKMPPSRRDRSKKKLLLKGSQKGICPKSPSAIPEQNHSLNDQAKGESHEYVTFSKLEDCHLQDRDLYPCPGTDCSRVFKQFKYLSVHLKAEHQNNDENAKHYLDMKNRREKCTYCRRHFMSAFHLREHEQVHCGPQPYMCVSIDCYARFGSVNELLNHKQKHDDLRYKCELNGCNIVFSDLGQLYHHEAQHFRDASYTCNFLGCKKFYYSKIEYQNHLSMHNVENSNGDIKKSVKLEESATGEKQDCINQPHLLNQTDKSHLPEDLFCAESANSQIDTETAENLKENSDSNSSDQLSHSSSASMNEELIDTLDHSETMQDVLLSNEKVFGPSSLKEKCSSMAVCFDGTKFTCGFDGCGSTYKNARGMQKHLRKVHPYHFKPKKIKTKDLFPSLGNEHNQTTEKLDAEPKPCSDTNSDSPDEGLDHNIHIKCKREHQGYSSESSICASKRPCTEDTMLELLLRLKHLSLKNSITHGSFSGSLQGYPSSGAKSLQSVSSISDLNFQNQDENMPSQYLAQLAAKPFFCELQGCKYEFVTREALLMHYLKKHNYSKEKVLQLTMFQHRYSPFQCHICQRSFTRKTHLRIHYKNKHQIGSDRATHKLLDNEKCDHEGPCSVDRLKGDCSAELGGDPSSNSEKPHCHPKKDECSSETDLESSCEETESKTSDISSPIGSHREEQEGREGRGSRRTVAKGNLCYILNKYHKPFHCIHKTCNSSFTNLKGLIRHYRTVHQYNKEQLCLEKDKARTKRELVKCKKIFACKYKECNKRFLCSKALAKHCSDSHNLDHIEEPKVLSEAGSAARFSCNQPQCPAVFYTFNKLKHHLMEQHNIEGEIHSDYEIHCDLNGCGQIFTHRSNYSQHVYYRHKDYYDDLFRSQKVANERLLRSEKVCQTADTQGHEHQTTRRSFNAKSKKCGLIKEKKAPISFKTRAEALHMCVEHSEHTQYPCMVQGCLSVVKLESSIVRHYKRTHQMSSAYLEQQMENLVVCVKYGTKIKEEPPSEADPCIKKEENRSCESERTEHSHSPGDSSAPIQNTDCCHSSERDGGQKGCIESSSVFDADTLLYRGTLKCNHSSKTTSLEQCNIVQPPPPCKIENSIPNPNGTESGTYFTSFQLPLPRIKESETRQHSSGQENTVKNPTHVPKENFRKHSQPRSFDLKTYKPMGFESSFLKFIQESEEKEDDFDDWEPSEHLTLSNSSQSSNDLTGNVVANNMVNDSEPEVDIPHSSSDSTIHENLTAIPPLIVAETTTVPSLENLRVVLDKALTDCGELALKQLHYLRPVVVLERSKFSTPILDLFPTKKTDELCVGSS
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein Rlf, Rearranged L-myc fusion gene protein, Zn-15-related protein.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PHOU_RHIME
Sequence: MSHAHIMSAFDEELKYLTRRISEMGGLAEQMVADSVRALVNSDLALAQKVISDDTILDDAERQIGEKAIVTIAKRQPMASDLREIMGSIRIAADLERVGDLGKNTAKRVIAVAGSGIPRKLARGLEHLAELALVQLKEVLDVYASRSPEKANSIRERDEEIDAIYTSLFRELLTYMMEDPRNITPCTHLLFCAKNIERIGDHATNIAETIYYMATGAQPQGERPKDDMTSTLGSVTD
What is the function of this protein?
Plays a role in the regulation of phosphate uptake.
What are the official names of this protein?
Phosphate-specific transport system accessory protein PhoU homolog, Pst system accessory protein PhoU homolog.
What is the protein family that this protein belongs to?
Belongs to the PhoU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAR2_ARATH
Sequence: MGQIPRFLSWRNMLVLSLAINFSLILKILKGDRERGDSWDRTAYVSIWPVVSTTASESSSLSSASCNYSKIEEDDDRIINLKFGDPTVYERYWQENGEVTTMVIPGWQSLSYFSDENNLCWFLEPELAKEIVRVHKVVGNAVTQDRFIVVGTGSTQLYQAALYALSPHDDSGPINVVSATPYYSTYPLITDCLKSGLYRWGGDAKTYKEDGPYIELVTSPNNPDGFLRESVVNSTEGILIHDLAYYWPQYTPITSPADHDVMLFTASKSTGHAGIRIGWALVKDRETARKMIEYIELNTIGVSKDSQLRVAKVLKVVSDSCGNVTGKSFFDHSYDAMYERWKLLKQAAKDTKRFSVPDFVSQRCNFFGRVFEPQPAFAWFKCEEGIVDCEKFLREEKKILTKSGKYFGDELSNVRISMLDRDTNFNIFLHRITSSFNSTL
What is the function of this protein?
Involved in auxin production.  Both TAA1 and TAR2 are required for maintaining proper auxin levels in roots, while TAA1, TAR1 and TAR2 are required for proper embryo patterning.  Involved in the maintenance of the root stem cell niches.
What are the official names of this protein?
Tryptophan aminotransferase-related protein 2.
What is the protein family that this protein belongs to?
Belongs to the alliinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PYRC_SHEON
Sequence: MKTLTITRPDDWHIHLRDGAQLTDTVRDISRYMGRAIVMPNLVPPAIDTETALAYYDRIKARVPAGSQFEPLMVLYLTDKTSPDEIRKAKASGKVFAAKLYPAGATTNSDSGVTDLKNIYPALEAMQEVGMLFLVHGEVTDSSIDIFDRERVFIENILSKIVTDFPNLKIVLEHITTKDAVDFVTQASDNVAATITAHHLLYNRNHMLAGGIRPHFYCLPILKRNTHQQALLAAAASGNKKFFLGTDSAPHAKDRKEAACGCAGSYTAHAAIELYAEAFESVNALDKLEAFASFNGPDFYNLPRNSDTITLVKKAWDIPASYPLGDTNVVPIRAGEQIDWQVE
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: RL1_WOLPM
Sequence: MNTYNDNPKQCLKKIVESASAKFNESVDIAVNLGVDSRKSEEQVRGTVVLPKGIGKNIKVAVFAQDKHLLEAEKAGADIAGGEDLVEEIKKGRKLDVDWCITTPDFMAKITPIAKVLGVKGLMPNPKFGTVTSNIAEAIKTIKSGQVKFGTDKNGVIHGKLGNIKFDIDDLLENLKAFLKVIKDNKPISAKGIYFKGVFLNSTMGKAYKIGKVEDII
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: RADA_METS3
Sequence: MVELEDLPSVGEKTAEKLRDAGFADMMRLATATPKELSVKAEIGEGVAEKVIEAARKSEKIDFETAYDVLERRRDVGHISVGSEGFNDLIGGGIETQSITEVFGEFGSGKSQISHELAVTVQLPPEKGGLDGECVFIDTENTFRPERIEQIANGFELDIDEVLQKIHVARAFNSSHQILMAEKINELIQQGNNIKLVIVDSLMAHFRAEYVGRESLAVRQQKLNQHLHALQQIANTYNVAVFITNQVQAKPDSFFGSPTKAIGGHVLGHASTYRIWLKKGLAGKRIARLVDSPHLPEGECVFKIKTEGIVD
What is the function of this protein?
Involved in DNA repair and in homologous recombination.  Binds and assemble on single-stranded DNA to form a nucleoprotein filament.  Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
What are the official names of this protein?
DNA repair and recombination protein RadA.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RecA-like protein family.