PharMolix/UniProtQA huggingface dataset:
Protein: PPIA_NOMLE
Sequence: MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE
What is the function of this protein?
Catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).  Exerts a strong chemotactic effect on leukocytes partly through activation of one of its membrane receptors BSG/CD147, initiating a signaling cascade that culminates in MAPK/ERK activation (By similarity).  Activates endothelial cells (ECs) in a proinflammatory manner by stimulating activation of NF-kappa-B and ERK, JNK and p38 MAP-kinases and by inducing expression of adhesion molecules including SELE and VCAM1 (By similarity).  Induces apoptosis in ECs by promoting the FOXO1-dependent expression of CCL2 and BCL2L11 which are involved in EC chemotaxis and apoptosis (By similarity).  In response to oxidative stress, initiates proapoptotic and antiapoptotic signaling in ECs via activation of NF-kappa-B and AKT1 and up-regulation of antiapoptotic protein BCL2 (By similarity).  Negatively regulates MAP3K5/ASK1 kinase activity, autophosphorylation and oxidative stress-induced apoptosis mediated by MAP3K5/ASK1 (By similarity).  Necessary for the assembly of TARDBP in heterogeneous nuclear ribonucleoprotein (hnRNP) complexes and regulates TARDBP binding to RNA UG repeats and TARDBP-dependent expression of HDAC6, ATG7 and VCP which are involved in clearance of protein aggregates (By similarity).  Plays an important role in platelet activation and aggregation (By similarity).  Regulates calcium mobilization and integrin ITGA2B:ITGB3 bidirectional signaling via increased ROS production as well as by facilitating the interaction between integrin and the cell cytoskeleton (By similarity).  Binds heparan sulfate glycosaminoglycans (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase A, PPIase A, Cyclophilin A, Cyclosporin A-binding protein, Rotamase A.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase A subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Nucleus. Note=Secretion occurs in response to oxidative stress in vascular smooth muscle through a vesicular secretory pathway that involves actin remodeling and myosin II activation, and mediates ERK1/2 activation.
Protein: ACYP_ACTSZ
Sequence: MIQRQFTVYGCVQGVGFRFFTAREANKLGIQGYVKNQADGSVRVVAAGSDRQVAAFRDWLEQGPPTAEVTNLLEQEYTGGRVFSDFTIER
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: MCA1B_ASPFC
Sequence: MYHRHSAPPPPGWSGGYPPRQQQWPPPQPYEYPPYPPQGPPPAHTFPPPAHRDYPSPYPTPPPHSPSPYQHPHHGHSQSWSVPAVPPRPPLEAQQFGNGAPSHYRFQYSACTGRRRALLIGINYIGQPNQLRGCINDVTNMSTFLHERYGYRREDMVILTDDQKNPLSIPTKANILRAMQWLVKDAQPNDSLFLHFSGHGGRTPDLDGDEEDGYDDVIYPVDYRVAGHIVDDEMHNIMVRPLRPGVRLTVIFDSCHSGTALDLPYVYSTQGILKEPNLAKEAAQDLFSAISSYGKGDLSGVAMTAIGFLKKAAKGDSARQRTVMTKTSPADVVMFSGSKDTQTSADTFQDGEARGALSWAFIKSLKQWPNQSYLQLLNSIRAQLDGKYTQKPQLSCSHPLDVNLLFVM
What is the function of this protein?
Involved in cell death (apoptosis) (By similarity).  Required for the apoptotic-like loss of membrane phospholipid asymmetry at stationary phase and facilitates growth under conditions of endoplasmic reticulum stress.
What are the official names of this protein?
Metacaspase-1B.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14B family.
Protein: YEAL_SALPA
Sequence: MFDVTLLILLGLAALGFISHNTTVAVSILVLIIVRVTPLNTFFPWIEKQGLTVGIIILTIGVMAPIASGTLPPSTLIHSFVNWKSLVAIAVGVFVSWLGGRGITLMGNQPQLVAGLLVGTVLGVALFRGVPVGPLIAAGLVSLIVGKQ
What are the official names of this protein?
UPF0756 membrane protein YeaL.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HSP7F_LACK1
Sequence: MSIPFGLDLGNNSSVLAVARNRGIDIIVNEVSNRSTPSLVGFGQKNRFLGESGKNKQTSNIKNTVDNLKRIVGLDYDHPDFEQESKYFSSKLVKLDDGKVGAQVRFAGKQQTFSATQLAAMYINKVKTTAVQETKGNITDVAIAVPAWYTEEQRYSIGDAAKIAGLNPVRIVNDVTAAAVSYGVFKTDLPEGEEKPRVVAFVDIGHSTYTCTIAAFKKGELKVLATAYDKHFGGRDFDRAITEHFADEFKTKYKIDIRENPKAYSRILAAAEKLKKVLSANTAAPFSVESVMNDVDVSSQLSREELEELVSPLLSRVTEPITKALAQANLTPEEVDYVEIVGGTTRIPSLKNAISEAFGKQLSTTLNQDEAIAKGAAFICAIHSPTLRVRPFKFEDIHPYSVSYSWDKQEEDEDHLEVFPAGSSYPSTKLITLQRTGDFSMQAKYTNKEELPEGTSAEIAKWDITGVQVSEGETSVPVKLKLRCDPSGLHIIEDAYTVEDIKVQELVPLPADAPEDAEPEYREVTKTVKKDTLTIIAHTFALEEKALNALIEKENELSAQDKLVAETEDRKNALEEYIYTLRGKLDEEYSDFASDDEKTRLKEMLAKAEDWLYDEGYDSIKAKYIAKYEELASLGNIIRGRYLAKEEEKRQALRSKQEASKMAELAEKLAAQRKAESEKKESKADAEGDVELD
What are the official names of this protein?
Heat shock protein homolog SSE1.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPG_BIFLO
Sequence: MNTENPIEKPFRKTGDPVDLTSESPLHPRRKSRRIMVGPVPVGGGAPISVQSMTNTLTANVPATLQQIAELTAAGCDIVRVAVPSQDDADALPEICRKSPIPVIADIHFQSKYVFQAIDAGCAAVRVNPGNIRKFDEVGPDICKAATDAGISLRIGVNAGSLDKELYAKYGGPTPEALVASALKEAHMFEDVGFHDFKISVKHHDVITMVETYRLLASKGDWPLHLGVTEAGPAWQGTIKSCLAFGALLAEGIGDTIRVSLSAPPAEEVKVGCKLLEYMGLRPRKFDIISCPSCGRAQVDVIQLASAVTEGLKDVTAPIRVAVMGCIVNGPGEAREADLGVASGNGKGQIFIKGKVIKTVPEDQIVDTLLTIANDIAAQMEADGQVPVNSTGPVVVPIQHPGH
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: LGT_UREU1
Sequence: MQLEIINPESTLINDVVAHRIAFSIGSNFNIYWYGIIFVCGFLLAILTYSLRLKFHYKVPYDPGFYYIFLAIPMTIIGARLWSLAIGDAKDFFDFRNGGLAIQGGVIAGVLSAAIYFPLILRMPKYHVRDLDADGNVIIRQPSMWIYADAIIPTILIGQALGRWGNFINGEIFGAESTVNDLQWLKKAMPAVFEGMKHYFIEGDKTLFTIYQPLFLYESFFNVIVFVFIYFGLSYIKQLKIGFVSMSYFFFYGVIRFSTESARAPQFSFAGTYVINSLLLIFGVLGALYVQFIAPILRKRFLLDAIIELFYKKKQQAHKFGQLRNPEEFLYYCHK
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS7_BACCZ
Sequence: MPRKGPVAKRDVLPDPMYNSKLVTRLINKMMVDGKKGKSQTILYNAFDIVSERTGKEPMEVFEQALKNIMPVLEVRARRVGGANYQVPVEVRPERRTTLGLRWLVNYARLRGEKTMEERLANEILDAANNAGASVKKREDTHKMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: FTHS_LIMRJ
Sequence: MTDIEIADQATLEPITEIAEKLGLSEDEIEQYGKYKAKIDLNVKPLPDKKHKLILVTSINPTPAGEGKSTVLIGLGDALNQLNYQTTIAMREPSMGPVFGIKGGATGGGYSQVVPMEDINLNFTGDLHALTSANNTLAALIDNYIMRDNAMNLDPRRIIWKRVEDVNDRALRNVVTGLGGPMAGVPRETGFDITAASELMAILCLSTSLHDLKERISRIVVGYTYDKEPVTVGQLNFQDAITIILKDALKPNLVQTLDHTPTIVHGGPFANIAHGCNSVLATQTALNLSDYTVTEAGFGADLGGEKFLDIKQRVLGKHPDAIVIVATVRALEYNGGAKLADLNEENLDALKKGMANLNRHIKNMQLYGLPIVVAINHFVSDTDKEIQMIKDDCAKQNVEAILTDAWAKGGKGTHDLANKVVELADSPSEFTHIYDVQVDDLQTKLEKIAKQIYGAKEVSFSRKAQNQLKRFAKYGWNDLPVCIAKTQYSFTDDQKQLGAPTDFTFHIRELVPKIGAGFVVALAGNMMTMPGLPKEPAAVNMMIDDNGKITGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: RLMH_COXB1
Sequence: MKINVVAVGKRLPAWIKAGFQSYADRLPRDFDLNLIEIAAFKRSKGADLKKIMLQESQQLIDAVPKESEIIVLDRLGEEVDTPTLAQKLSQWRHENRSISLLIGGPEGLSATCIDKARWVWSLSALTLPHALARVIVAEQIYRAWSIITNHPYHR
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIM_BACC0
Sequence: MNTKEISKVVDLVRESNPLVHNITNVVVTNFTANGLLALGASPVMAYAKEEVAEMASIAGALVLNMGTLRPDEVEAMLLAGKSANRNDVPVLFDPVGAGATSYRTEVARHIPAEIELAIIRGNAAEIANVINEKWEIKGVDAGAGNGNVVSIAKQAADELNTVAVITGKEDVVTDGERTIVIRNGHSILTKITGTGCLLTSVIGAFVAVEKDYVKAAVAALTFYGVAAELAAAKTVEKGPGSFQIEFLNQLANTTSGDIEKYGKIEVI
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: Y5285_ARATH
Sequence: MSINIGEISIPDLPIFFSMFLTIYLIAYFIVFRNWKPQIRPEASSCLISIFHGSPAVFLATRAVFSSSERSFASANTAAQNTVLDFSVAYFLTDLFHYIVFNPNDVLFIGHHVATLFVFLTCRFLVFHGACAILGLLILAEVTSACQNAWTLAGARKNDPESRLAVKVYDLLSPPFYAFYSIVRGVLGPLFFGKMVAFYARGGAHGVIPNWLWISWAIVVGIAITVSILWIWNLWIELFSERKANKIRVDKKIR
What are the official names of this protein?
TLC domain-containing protein At5g14285.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SYS_WOLTR
Sequence: MHDIEYIRQNSEEFEKAMESRGMKEFSAEEILKVDHKKRLLTTKLQDLNRQRNEITKKIKELKMSKSPCEKQIKSSKNITNEIEAISLKEQMEKDKLVNILSNLPNIPVQGVPIGAGENSNLEVRRYREKRQFDFVPKSHYELGERLGLMDFEQAAKISGSRFAILKGQLAKLGRALINFMLEMHVNEFGYTEVYHPVLVKNEAMYNVGQLPKFSDDSYLTTDELRLIPTGEVVLTNSVADKIVEEKKLPIRFTAYSECFRKEAGSAGQSTRGMIRQHQFGKVELVSITTEDQSNDELERMTGVAEEILKRLELPYRVILLCSGDMGFAAQKTYDIEVWLPEQNRYREISSCSNCGNFQARRMNAKYSLEANKKVKKYVHTLNGSALAIGRTIIAVMENYQNPDGSITIPNVLQKYISNGTVISK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RFCL_PYRFU
Sequence: MPELPWVEKYRPKKLSEIVNQEEAIEKVRAWIESWLHGHPPKKKALLLAGPPGSGKTTTVYALANEYNFEVIELNASDERTYEKISRYVQAAYTMDILGKRRKIIFLDEADNIEPSGAKEIAKLIDKAKNPIIMAANKYWEVPKEIREKAELVEYKRLTQRDVMNALIRILKREGITVPKEILLEIAKRSSGDLRAAINDLQTVVVGGYEDATQVLAYRDVEKTVFQALGLVFGSDNAKRAKMAMWNLDMSPDEFLLWVDENIPHLYLNPEEIAQAYDAISRADIYLGRAARTGNYSLWKYAIDMMTAGVAVAGRKRRGFVKFYPPNTLKILAESKEEREIRESIIKKIIREMHMSRLQAIETMKIIREIFENNLDLAAHFTVFLGLSEKEVEFLAGKEKAGTIWGKALALRRKLKELGIREEEKPKVEIEEEEEEEEKTEEEKEEIEEKPEEEKEEEKKEKEKPKKGKQATLFDFLKK
What is the function of this protein?
Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.  The complex possesses DNA-dependent ATPase activity which is further stimulated by PCNA.
What are the official names of this protein?
Replication factor C large subunit, RFC large subunit, Clamp loader large subunit, PfuRFC large subunit.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family. RfcL subfamily.
Protein: FOLD_FRATN
Sequence: MILIDGKSLSKDLKERLATQVQEYKHNTAITPKLVAIIVGNDPASKTYVASKEKACAQVGIDSQVITLPEHTTESELLELIDQLNNDSSVHAILVQLPLPAHINKNNVIYSIKPEKDVDGFHPTNVGRLQLRDKKCLESCTPKGIMTMLREYGIKTEGAYAVVVGASNVVGKPVSQLLLNAKATVTTCHRFTTDLKSHTTKADILIVAVGKPNFITADMVKEGAVVIDVGINHVDGKIVGDVDFAAVKDKVAAITPVPGGVGPMTITELLYNTFQCAQELNR
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: OXYR_PECCC
Sequence: MNIRDLEYLVALAEHRHFRRAADSCHVSQPTLSGQIRKLEDELGVMLLERTSRKVLFTQAGLLLVEQARTVLREVKVLKEMASQQGETMSGPLHIGLIPTVGPYLLPQIIPMLHRTFPKLEMYLHEAQTHQLLAQLDSGKLDCAILAMVKESEAFIEVPLFDEPMKLAIYQDHPWANRERVAMSDLAGEKLLMLEDGHCLRDQAMGFCFQAGADEDTHFRATSLETLRNMVAAGSGITLLPALSVPRERERDGVCYLPCYKPEPKRTIALVYRPGSPLRGRYEQLADTIREHMQGYMETLSK
What is the function of this protein?
Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione-reductase.
What are the official names of this protein?
Hydrogen peroxide-inducible genes activator.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: U496F_ARATH
Sequence: MEFCGCLSELMNGESSSKRNGPSTLPVKEVRTDMRSKYSSDLSSYTSACKKDSNLKSFDSSLHQRTNIIITSLAARAETQSLNLDSLMEVYGFLLELNQNAVRVIIESREDVWKNKDLKSLVDVYFKSTSKTLDFCNTVENCVKRTEISQLIIRFAVKQFEAESVDTDLGGDKKKKKYTKTLEELNKFKAMGDPFDGELVTQFDSVYDQQVLFLEELRKQRRKLDKKQRNVKTLRTVSNVFFATAYVSVLVLSVVATTMSAPPVVCAVASGSTAPIEITGKWFSQMWKKYEKAVKRQRGLVLTMESRVQVNNEAMKNIRSDVDELRSWVSSILETVDFAVEREEEEEAMGLAMQGIKKHVDGFTEKMEEVGENAAKCSKFIALGRLLVLEHILGLPAN
What are the official names of this protein?
UPF0496 protein At5g66660.
What is the protein family that this protein belongs to?
Belongs to the UPF0496 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CLL1_ARATH
Sequence: MATILFKVIMMKELILLEEGWSVMKTGVAKLQRILEDLSEPPFDPGQYINLYTIIYDMCLQQPPNDYSQELYNKYRGVVDHYNKETVLPSMRERHGEYMLRELVKRWANHKILVRWLSRFCFYLDRFYVARRGLPTLNDVGFTSFHDLVYQEIQSEAKDVLLALIHKEREGEQIDRTLVKNVIDVYCGNGVGQMVIYEEDFESFLLQDTASYYSRKASRWSQEDSCPDYMLKAEECLKLEKERVTNYLHSTTEPKLVEKVQNELLVVVAKQLIENEHSGCLALLRDDKMGDLSRMYRLYRLIPQGLEPIADLFKQHVTAEGNALIKQAADAATNQDASASQVLVRKEIELHDKYMVYVDECFQKHSLFHKLLKEAFEVFCNKTVAGASSAEILATYCDNILKTRGGSEKLSDEATEITLEKVVNLLVYISDKDLFAEFYRKKQARRLLFDRSGIMKEVTDITLARELQTNFVDYLSANMTTKLGIDFTVTVLTTGFWPSYKTTDLNLPTEMVNCVEAFKVFYGTKTNSRRLSWIYSLGTCHILGKFEKKTMELVVSTYQAAVLLLFNNAERLSYTEISEQLNLSHEDLVRLLHSLSCLKYKILIKEPMSRTISKTDTFEFNSKFTDKMRKIRVPLPPMDERKKVVEDVDKDRRYAIDAALVRIMKSRKVLAHQQLVSECVEHLSKMFKPDIKMIKKRIEDLINRDYLERDTENANTFKYVA
What are the official names of this protein?
Putative cullin-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the cullin family.
Protein: ACT3_ORYSI
Sequence: MADGEDIQPLVCDNGTGMVKAGFAGDDAPRAVFPSIVGRPRHTGVMVGMGQKDAYVGDEAQSKRGILTLKYPIEHGIVNNWDDMEKIWHHTFYNELRVAPEEHPILLTEAPLNPKANREKMTQIMFETFNAPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDCLMKILTERGYSFTTTAEREIVRDIKEKLAYIALDYEQELETAKSSSSVEKSYELPDGQVITIGAERFRCPEVLFQPSLIGMEAPGIHETTYNSIMKCDVDIRKDLYGNIVLSGGTTMFPGIADRMSKEITALAPSSMKIKVVAPPERKYSVWIGGSILASLSTFQQMWISKGEYDESGPSIVHRKCF
What is the function of this protein?
Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth.
What are the official names of this protein?
Actin-3.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RIMP_ACTPJ
Sequence: MATLEQKLEELVSDTIESMGFELVGIECQRAGRFLTVRLYIDKEGGVTIDDCSDVSRQVSAILDVEDPIADKYNLEVSSPGLDRPLFTLAHYQRFIGQEIVIHLRIPMFDRRKWQGKLESVEGDLITLTVDNETRQFAFGNIQKANLVPVFNF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_AQUAE
Sequence: MEKFVDRVKIFVKGGKGGDGAVAFLREKYRPKGGPAGGDGGKGGDVILVATSSKHTLLDFKYKKHYIAQNGEPGKGKKMHGKDGEDLIIYVPVGTVVKDAQTGEVICDLVKEGQKCIVAKGGKGGRGNARFATPTNQAPTYAEKGQKGEERWIILELKLIADVGLVGFPNAGKSTLLSRLTRAKPKIADYPFTTLSPNLGVMELDWERRLVIADIPGLIEDAHKGAGLGHEFLRHIERTKFLAHVIDVSDFREREPVQAFEAINRELELYSPKLAQKPQIVVANKIDALSDRSLLSELEKYFKEKGYEFYAVSALTGEGIEELKEGLWKKYEEIRDKESAQVT
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_CLAM3
Sequence: MALDDIHTPVLLERCLELLAPALQGEGAVLVDATLGMAGHSEAFLDALPGLRLVGLDRDPDALAIAGERLARFGDRVNLVHTVYDGIGRALDGLGIGEVQGVFFDLGVSSLQLDRVERGFSYSQDAPLDMRMDGTAGLTAAQVVAEYDELELRRIFYDYGEEKLAPRYASRIVQAREVEPITTSARLVEIIQQATPAAVQRAGHPAKRVFQALRIEVNQELSVLARAMPAAVDRLAVGGRVVVESYQSLEDRIVKRELRARSTSTAPVGLPVELPEHRPELKLLVRGAELADQHEIAQNPRAASVRLRAAERARRRHA
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1159_HAEIN
Sequence: MIAAQFRIQALPTTYLFKEAQALDAFPSVLDKSSLIQRLSIILPKEEDLKFQQALDFLQVENYEAALPLLKDAWELSDKKNSDVALLYAETYIAMKKTEPAQEILNQIPLQDRDSRWHGLQAQIELQIQAADTPEIQQLQADYAKNPTAEIAIKLAVQLHQAGRNEEALTLLFGILKTDLGAQNGEVKQQFLSILSAMGNADPLTNKFRRLLYSLLY
What are the official names of this protein?
Uncharacterized protein HI_1159.
Protein: COX1_BALMU
Sequence: MFMNRWLFSTNHKDIGTLYLLFGAWAGMVGTGLSLLIRAELGQPGTLIGDDQVYNVLVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLMASSMIEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMTQYQTPLFVWSVLVTAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMIWAMVSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPALMWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFSGYTLNTTWAKIHFLIMFVGVNLTFFPQHFLGLSGMPRRYSDYPDAYTTWNTISSMGSFISLTAVMLMIFIIWEAFTSKREVLAVDLTYTNLEWLNGCPPPYHTFEEPAFVNPKWS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GGPP7_ARATH
Sequence: MTTLNLSIFPSVKISSSASIPGFIKIQPFLLRRKLSTVLSVTARDEGIIHNHFDFTSYMIGKANAVNEALDSAVSLREPIKIHEAIRYSLLARGKRVRPVLCIAACELVGGEESVALPAACAVEMIHTMSLIHDDLPCMDNDDLRRGKPTNHKVFGEDVAVLAGDALISFAFEHLATSTAVSPARVVRAIGELAKAIGSKGLVAGQVVDLTSGGMDQNDVGLEVLEFIHVHKTAVLLEAATVLGAIVGGGSDEEVEKLRRFARCIGLLFQVVDDILDVTKSSEELGKTAGKDLIADKLTYPKLMGLEKSKDFADKLLSDAHEQLHGFDSSRVKPLLALANYIAKRQN
What is the function of this protein?
Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate.
What are the official names of this protein?
Geranylgeranyl pyrophosphate synthase 7, chloroplastic, GGPP synthase 7, GGPS7, (2E,6E)-farnesyl diphosphate synthase 7, Dimethylallyltranstransferase 7, Farnesyl diphosphate synthase 7, Farnesyltranstransferase 7, Geranyltranstransferase 7.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PNP_AKKM8
Sequence: MSIHSVECNVGTNPITIETGKMARLADGAVVVRSGDTVVLVTVVSATKVKEGQTFFPLSVEYKEKAAAAGMFPGGYFKREGRPTEKEILTCRMTDRPLRPMFPKGYFYDTQVITLLLSADGENEPDILSINGASAACVVSDLPFAEPVGAVRVGRIDGQFVINPTNSQREHSQLDLVFAGTKDQVIMIEGSANELPEEDFIAALRVAQENVKVICEKQEELRAVCGKEKRAYELCLAKPELLEIGYEIAGDRIEEAIYAPSKVERQKKVGALRDEVEAAIKERHPEATDFDVEQVFEYIQKKAFRISIMEKDKRADGRALKQLRPLTAEVNVLPPVVHGSAMFARGETMSLCLATLAPMEERQYMDNYTGSVNEKRFILHYNFPPFSVGDTGRFGGQNRREIGHGALAERSIAPVVPGEQEFPYAIRVSSEIMESNGSTSMASVCAGTMSLLAAGVPLKRPVAGISVGLVTEQNDQHEITSYKTLLDIIGSEDFYGDMDFKLCGTSEGVTGYQLDLKLPGIPLSILEEAIHVAKAGRTDVLKVMNEAIAAPAQMSPNAPRIETTKIPADRIGELIGPGGKNIKAIQAESGADINIEEDGTVHIYAAKQEGLDRALELVTRMFKTIEIGELYTGKIVSTTTFGAFMEVLPGKDGLIHISELAEGRTAKTEDVVSVGDVVTAKCIGIDDKGRVKMSIRAALRDAKAAEAEAAGITE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPO4_STRR6
Sequence: MLIFPLLNDLSRKIIHIDMDAFFAAVEIKDNPKLRGKPVIIGSDPRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKAVGLQIRAIFKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKFLAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLEVPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKELTLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSIAQKTQDASQISQIALQLYEELSEKERGVRLLGITMTGF
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.