PharMolix/UniProtQA huggingface dataset:
Protein: MOAC_SALPB
Sequence: MSQLTHINAAGEAHMVDVSAKAETVREARAEAFVTMRSETLAMIVDGKHHKGDVFATARIAGIQAAKRTWELIPLCHPLLLSKVEIQLQAEPEHNRVRIESLCRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGPVRLLAKSGGKSGDFKVDAHD
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: AROC_CORGB
Sequence: MLRWTTAGESHGQALIATVEHMPAGVPVTKDEVSYQLARRRLGYGRGARMKFEQDALTFLTGIRHGLTLGSPISIMIGNTEWDKWTTIMSSDALDMEDPDNVAAMSSGRGAKLTRPRPGHADYAGMLKYGFDDARNVLERSSARETAARVAAATVARSFLRETLGVEVLSHVISIGASEPYVGAEPTFADIQAIDDSPVRAFGKDAEKSMIAEIEAAKKAGDTLGGIVEVIVEGLPIGLGSHISGEDRLDAQIAAALMGIQAIKGVEIGDGFEEARRRGSEAHDEVFLDDNGVYRNTNRAGGLEGGMTNGETLRVRAGMKPISTVPRALKTIDMENGKAATGIHQRSDVCAVPAAGVVAEAMVTLVLARAVLQKFGGDSLSETKSNIDTYLKNIEERMKFEGLEDGA
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: G3P_PELSI
Sequence: MVKIGVNGFGRIGRLVTRAAFTCDKVQIVAINDPFIDLNYMVYMFKYDSTHGRFHGTVKAENGKLVINGQAITIFQERDPANIKWGDAGAEYVVESTGVFTTTEKASAHLKGGAKRVVISAPSADAPMFVMGVNHEKYDNSLKVVSNASCTTNCLAPLAKVIHDNYGMVEGLMTTVHAITATQKTVDGPSGKLWRDGRGAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSVVDLTCRLQKPAKYDDIKKVMKAASEGPLKGILGYTEDQVVSSDFNGDSRSSIFDAAAGIALNDNFVKLVSWYDNEFGYSNRVVDLLVHMASKE
What is the function of this protein?
Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively.  Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate (By similarity).  Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis.  Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC (By similarity).
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, Peptidyl-cysteine S-nitrosylase GAPDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Nucleus.
Protein: RUVB_HALH5
Sequence: MEERMVSAEAQTEEAAVEQGIRPHSFEQYIGQEKVKQNLKVFIEAAKMREEALDHVLLYGPPGLGKTTLSTIIANELGVQMRTTSGPAIERPGDLAAILTALEPGDVLFIDEIHRLNRMVEEVLYPAMEDYCIDIVIGKGPTARSVRLDLPPFTLVGATTRAGMLSSPLRDRFGVMARLEYYNVEELTTIIERTATIFDTELERDASIEIARRSRGTPRIANRLLRRVRDFAQVSGDMRISSSRAIESLERLQVDRLGLDHIDHKLIKGIMTKFNGGPVGLETISATIGEETDTIEEVYEPYLLQIGFLQRTPRGRVVTPLAYEHFNMEVPNK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: HSP1_NINYV
Sequence: MARYRRHSRSRSRSRYRRRRRRRSRHHNRRRTYRRSRRHSRRRRGRRRGYSRRRYSRRGRRRY
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex (By similarity).
What are the official names of this protein?
Sperm protamine P1.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: PLSX_VESOH
Sequence: MAIKVSIDASGGDYGIPVTIVAGIKALNIFQDLHLYFVGNEPSITTELGKYPSNTLNSRYTIIHASEVVLMNESPAIALRKKKDSSMRIAINLVKTFKADACVSAGNTGALMAISRFVLRTIKGIDRPAIMGRMPTITGHTHMLDLGANVDSKPKALVEFATMGSIAVKHTENIESPTIGLLNIGEEDMKGSEKIRKAATLLKASNLNYVGFVEGNDIYKGIVDLIVCDGFEGNIALKASEGVASMMEHYLKQAFTRNLLTKLVSLIAIPVLKDFKSSLNPDKYNGASLLGLRGIVVKSHGSANIDSFLTAITEAYIEAHAKISDKISLQISKELEHNE
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: MTRE_METTM
Sequence: MDPMITGLGVVALMGAAATIAGAAEDLESDVGSQSNPNSQVQLAPQMGHLHRIINKAVSGEPVAYGTWCGIAGSVAFVLMNSMQLPVIMAIAIGAVIAAMVHTTYAVTSHMGRIVSQSQFNQPLFMDMLVQHLGPIAGHGFIVTFCTVGLSYLMTLPIPGFAHPFPLPLLAVLWGITIGAIGSSTGDVHYGAEREYQQYPFGGGIPVAIHGDITTKAELGARNSMDVVHFCAKYGGPLTGFAFGAIVFLSFWNTIVFGITGGIISGLIIVLLLIILNNRLEVFARNRYGPYKEEE
What is the function of this protein?
Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin.  This is an energy-conserving, sodium-ion translocating step.
What are the official names of this protein?
Tetrahydromethanopterin S-methyltransferase subunit E, N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit E.
What is the protein family that this protein belongs to?
Belongs to the MtrE family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: URED_SYNS9
Sequence: MQRLNPWHGTCRLQFSADADTTHHQGGCTAPFKLMRAERGNDGRCELPLLHSAGGLVGGDQLSVDLELGRNSRALITSVAAQKVYGSIGRSRLHPKGTWANQSVSCRLGSNSDLEWLPQELVVYADALVEQSLDVQLADDASFLSAEIVRLGRTAAGEDLGQGCWRSAVSLRRIGENGTRWEQVDRLELSGDALHHRHGLNGDAVFGTLIWAAPAPLTNPTLKSLLTNARNDRAGLEGQMQCSRLEQGLIARYVGPSSRDARFWFSRIWARTRAQRQLSEPRIPRVWPLQEQPLRQQVFIENIASSNAATH
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALR1_CLOAB
Sequence: MFRHIRPVWAEIDLDNIAYNMQQIRRCSKSDEIIGVVKADAYGHGAVDVAPVLLENGANRLAVAVISEAVELRKSGIQCPIMILGYTPLSLVDSIIKYSIEQTVFSYDYAEKLSEAARQKNITLRIHIALDTGMGRIGFLPTEESVWEVYKISKLSNIIIEGIFSHFSTSDETNKEYTYAQLKKFEWFYNELRKKNIKINIRHIGNSAAIMELPETHFEATRPGIILYGYYPSNEVDKNKLNLKPIMTLKTNVVHIKKMMPGEYVSYGRKFKCERESIIATLPVGYADGYTRMLSGKAKVIINGNYAPVIGRICMDQCMIDITDLPSVQVGDEVVIMGESDDKKFTADDMAEIIGTINYEVICMISKRVPRVYIKNGEVVKIRNYV
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase 1.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: FTSP_PECAS
Sequence: MSLNRRQFIQASGLALCAGMTPLAAKASGNPAALPIPPLLESRRGQPLFLTMQRAHWAFSGDRKTSIWGINGRYLGPTVRVYDGDDVKLIYSNRLNEPVAMTIGGLQVPGPLMGGAARIISPGGDWSPVLPIRQSSATCWYHANTPNRMAPHIYNGLVGLWLVEDSTSKSLPLPNHYGVDDFPLIIQDKRLDNFGVPLYNPPSSGGFVGDSLLVNGVQSPFVEVSRGWVRLRLLNASNSRRYVMRLSDGRAMNVIASDQGLLPAPMAVNQLSLAPGERREILIDMSQGEEVTLTAGESAGIMDRLRGLFEPSSILISTQILTLKPTGLLPLVTDNLPMRLLADNIIEGSISRTREFRLGDSLPGINGAMWDMTRADVQTQLGRCERWIIHADTPQAFHIQGVKFLVRSANGRPPAVEDSGWKDTVWIDNDVELLVYFMQPSSMAFPFLYYSQTLELADRGSTGQLIVQSAM
What is the function of this protein?
Cell division protein that is required for growth during stress conditions.  May be involved in protecting or stabilizing the divisomal assembly under conditions of stress.
What are the official names of this protein?
Cell division protein FtsP.
What is the protein family that this protein belongs to?
Belongs to the FtsP family.
What are the subcellular locations of this protein?
Periplasm. Note=Localizes to the division septum.
Protein: ST7_CAVPO
Sequence: MAEAATGFLEQLKSCIVWSWTYLWTVWFFIVLFLVYILRVPLKINDNLSTVSMFLNTLTPKFYVALTGTSSLISGLILIFEWWYFRKYGTSFIEQVSVSHLRPLLGGVDNNSNNSNSSNGDSDSNRQSVSECKVWRNPLNLFRGAEYNRYTWVTGREPLTYYDMNLSAQDHQTFFTCDSDHLRPADAIMQKAWRERNPQARISAAHEALEINEIRSRVEVPLIASSTIWEIKLLPKCATAYILLAEEEATTIAEAEKLFKQALKAGDGCYRRSQQLQHHGSQYEAQHRRDTNVLVYIKRRLAMCARRLGRTREAVKMMRDLMKEFPLLSMFNIHENLLEALLELQAYADVQAVLAKYDDISLPKSATICYTAALLKARAVSDKFSPEAASRRGLSTAEMNAVEAIHRAVEFNPHVPKYLLEMKSLILPPEHILKRGDSEAIAYAFFHLAHWKRVEGALNLLHCTWEGTFRMIPYPLEKGHLFYPYPICTETADRELLPSFHEVSVYPKKELPFFILFTAGLCSFTAMLALLTHQFPELMGVFAKAMIDIFCSAEFRDWNCKSIVMRVEDELEIPPASQSQHFQN
What are the official names of this protein?
Suppressor of tumorigenicity 7 protein.
What is the protein family that this protein belongs to?
Belongs to the ST7 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DB3L_DIOPO
Sequence: MSSSTLFHLFLLSSLLFSCLSNARPDEDDFSYIEGSPNGPENWGNLNPEWKTCGNGMEQSPINLCDDRVIQTPALGKLRTSYQAARATLKNNGHDIMVNFKSDAGSQFINQVRYQLKRIHFHSPSEHVLNGERFDLEVQMVHESQDQRRAVTAILFRFGRSDPFLSDLEDFISQISKSEKNEVDAGVVDPRQLLQFDDPAYYRYMGSFTAPPCTEDITWTVIKKLGTVSPRQVLMLKQAVNENAINNARPLQPLKFRTIFFYPRQKSNHDAI
What is the function of this protein?
Maltose-binding lectin.  No affinity is detected toward glucose.  Has hemagglutinating activity against rabbit erythrocytes at 3. 9 ug/ml.  No carbonate dehydratase or trypsin inhibitor activity detected by measuring the hydrolysis of 4-nitrophenyl acetate or the inhibition of bovine trypsin-catalyzed hydrolysis of N-benzoyl-L-arginine ethyl ester, respectively.
What are the official names of this protein?
Dioscorin DB3L, Tuber storage protein DB3L.
What is the protein family that this protein belongs to?
Belongs to the alpha-class carbonic anhydrase family.
Protein: HIS8_STAA1
Sequence: MKEQLNQLSAYQPGLSPRALKEKYGIEGDLYKLASNENLYGPSPKVKEAISAHLDELYYYPETGSPTLKAAISKHLNVDQSRILFGAGLDEVILMISRAVLTPGDTIVTSEATFGQYYHNAIVESANVIQVPLKDGGFDLEGILKEVNEDTSLVWLCNPNNPTGTYFNHESLDSFLSQVPPHVPVIIDEAYFEFVTAEDYPDTLALQQKYDNAFLLRTFSKAYGLAGLRVGYVVASEHAIEKWNIIRPPFNVTRISEYAAVAALEDQQYLKEVTHKNSVERERFYQLPQSEYFLPSQTNFIFVKTKRVNELYEALLNVGCITRPFPTGVRITIGFKEQNDKMLEVLSNFKYE
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: RFPL1_HUMAN
Sequence: MKRLSLVTTNRLSPHGNFLPLCTFPLAVDMAALFQEASSCPVCSDYLEKPMSLECGCAVCFKCINSLQKEPHGEDLLCCCCSMVSQKNKIRPSWQLERLASHIKELEPKLKKILQMNPRMRKFQVDMTLDADTANNFLLISDDLRSVRSGCITQNRQDLAERFDVSICILGSPRFTCGRHYWEVDVGTSTEWDLGVCRESVHRKGRIHLTTERGFWTVSLRDGSRLSASTVPLTFLFVDRKLQRVGIFLDMGMQNVSFFDAEGGSHVYTFRSVSAEEPLHLFFAPPSPPNGDKSVLSICPVINPGTTDAPVHPGEAK
What is the function of this protein?
Negatively regulates the G2-M phase transition, possibly by promoting cyclin B1/CCNB1 and CDK1 proteasomal degradation and thereby preventing their accumulation during interphase.
What are the official names of this protein?
Ret finger protein-like 1, RING finger protein 78.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=A higher concentration is observed in the cytoplasm compared to the nucleus.
Protein: DXS_CORGB
Sequence: MGILNSISTPADLKALNDEDLDALAKEIRTFLVDKVAATGGHLGPNLGVVELTIGLHRVFDSPQDPIIFDTSHQSYVHKILTGRAKDFDSLRQKDGLSGYTCRAESEHDWTESSHASAALSYADGLSKAKQLDGDTTHSVVAVVGDGALTGGMCWEALNNIAAGKDRKVVVVVNDNGRSYSPTIGGFAENLAGLRMQPFYDRFMEKGKTSLKSMGWVGERTFEALHAFKEGVKSTVIPTEMFPELGMKYVGPVDGHNQKAVDNALKYAHDYDGPIIVHMVTEKGRGYAPAEQDLDELMHSTGVIDPLTGAPKSASKPGWTSVFSDELVKIGAQNENVVAITAAMAGPTGLSKFEANFPNRFFDVGIAEQHAVTSAAGLALGGKHPVVAIYSTFLNRAFDQLLMDVGMLNQPVTLVLDRSGVTGSDGASHNGVWDMALTSIVPGVQVAAPRDEDSLRELLNEAISIDDGPTVVRFPKGDLPTPIVAIDTLEDGVDVLAYEDATEDDAPSVLIVAVGERATVALEVASRITQHGVNVTVVDPRWIVPIPQSLVALSDDHDLVITIEDGVIHGGVGSLLSDALNASEVDTPRRQIAVPQKYLDHASRSEVFADYGLDADGIETTVVGWLDSLFGE
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: NORC_PSEAE
Sequence: MSETFTKGMARNIYFGGSVFFILLFLALTYHTEKTLPERTNEAAMSAAVVRGKLVWEQNNCVGCHTLLGEGAYFAPELGNVVGRRGGEEGFNTFLQAWMNIQPLNVPGRRAMPQFHLSEGQVDDLAEFLKWSSKIDTNQWPPNKEG
What is the function of this protein?
Component of the anaerobic respiratory chain that transforms nitrate to dinitrogen (denitrification).
What are the official names of this protein?
Nitric oxide reductase subunit C, NOR small subunit, Nitric oxide reductase cytochrome c subunit.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=May be attached to the membrane by a signal-anchor.
Protein: SYC_PYRAE
Sequence: MGVRIYNTATRQVEEFVTYVPKLARGYVCGITPYDHVHVGHGRVYVFFDMFRRYLEARGYEVRLVINFTDIDDKIINKAREEFGHDAYKRWKEVPERYIAEFFEMSNKLFIKPAHAYPRVTENVNEMVAWISTLVEKGYAYVAPDGSVYFEVGKVPNYGVLSRQKIEELIAGARVEPEPGKKNPLDFALWKSWTPGEPWWNSPWCPGRPGWHLECVVMSTKYLGAPFDFHGGGADLIFPHHENEIAIAKAYYGLDNFAKYWIHVGYLTVRGEKMSKSLGNVITLREVLSKYSGEALRLAYAMSHYRKPMEFSFELLDQAEEMVKTLYTAYDELSQAVADASDEDKEKLEYGKYIESFYAALEDDFSTPQAAQQLYGLARYIISTVLHRIDKASRQTAIDVLTQYVKMADILGVLERREIPKEVEEVIKAVVEARARLRREKMYQLADYLRERLAGIGVELHDFGQRTYYTYKRR
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KITH_SHIDS
Sequence: MAQLYFYYSAMNAGKSTALLQSSYNYQERGMRTVVYTAEIDDRFGAGKVSSRIGLSSPAKLFNQNSSLFAEIRAEHEQQAIHCVLVDECQFLTRQQVYELSEVVDQLDIPVLCYGLRTDFRGELFIGSQYLLAWSDKLVELKTICFCGRKASMVLRLDQAGRPYNEGEQVVIGGNERYVSVCRKHYKEALEVGSLTAIQERHRHD
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXS_STAS1
Sequence: MSKVTGSERVKRGMAEMQKGGVIMDVVNAEQAKIAEEAGAVAVMALERVPSDIRAAGGVARMANPKIVEEVMNAVSIPVMAKGRIGHITEARVLESMGVDYIDESEVLTPADEEYHLRKDTFTVPFVCGCRNLGEAARRIGEGAAMLRTKGEPGTGNIVEAVRHMRQVNSEVSRLTVMNDDEIMTEAKNIGAPYEVLKNIKENGKLPVVNFAAGGVATPQDAALMMELGADGVFVGSGIFKSEDPEKFAKAIVQATTHYQDYELIGRLAKELGIAMKGLDINDLSLEERMQERGW
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: OR4CB_HUMAN
Sequence: MQQNNSVPEFILLGLTQDPLRQKIVFVIFLIFYMGTVVGNMLIIVTIKSSRTLGSPMYFFLFYLSFADSCFSTSTAPRLIVDALSEKKIITYNECMTQVFALHLFGCMEIFVLILMAVDRYVAICKPLRYPTIMSQQVCIILIVLAWIGSLIHSTAQIILALRLPFCGPYLIDHYCCDLQPLLKLACMDTYMINLLLVSNSGAICSSSFMILIISYIVILHSLRNHSAKGKKKALSACTSHIIVVILFFGPCIFIYTRPPTTFPMDKMVAVFYTIGTPFLNPLIYTLRNAEVKNAMRKLWHGKIISENKG
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 4C11, Olfactory receptor OR11-136.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GLNB_MYCTU
Sequence: MKLITAIVKPFTLDDVKTSLEDAGVLGMTVSEIQGYGRQKGHTEVYRGAEYSVDFVPKVRIEVVVDDSIVDKVVDSIVRAARTGKIGDGKVWVSPVDTIVRVRTGERGHDAL
What is the function of this protein?
In nitrogen-limiting conditions, when the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP.  P-II-UMP allows the deadenylation of glutamine synthetase (GS), thus activating the enzyme.  Conversely, in nitrogen excess P-II is deuridylated and promotes the adenylation of GS.  P-II indirectly controls the transcription of the GS gene (glnA).  P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA.  When P-II is uridylylated to P-II-UMP, these events are reversed (By similarity).
What are the official names of this protein?
Nitrogen regulatory protein P-II.
What is the protein family that this protein belongs to?
Belongs to the P(II) protein family.
Protein: GLND_RHOPA
Sequence: MSPSRPAADERFDSARVAAEIATLAEKHTGNDAAFRTALAMLMKAELAKARTEAEAQLLRDRHGRRCAERLCYVQDAIIRLLFNAATEYLYNTPTPSSSERMTVVATGGYGRGLMAPESDIDLLFILPYKQTAWGEQVAEVILYCLWDIGLKVGHATRSVDECIRQARADMTIRTAILETRFLAGDEALYAELVERFDKEVVEGTAAEFVAAKLAEREERHRRSGQSRYLVEPNVKDGKGGLRDLHTLFWIAKYVYRVREASELSERGVFDPAEFRTFRRCEDFLWSVRCNIHFVTKRAEDRLSFDLQREIGVRLGYTSHPGMQDVERFMKHYFLIAKEVGNLTAILCAKLEDQQAKAAPALTRMMARLRPAAKRRRVPESDDFVIDNNRINLAVPDVFKHDPVNLIRIFRLAQKNNLAFHPDAMRSVTRSLSLITPQLRDNPEANRLFVEILTSDNAEPVLRRMNETGVLGRFIRAFGRIVSMMQFNMYHSYTVDEHLIRCVGNLQEIERGGNDEFALSSELIRKIRPDHRAVLYAAVLLHDIAKGQPEDHSTAGAKVARRLCPRFGFSTADTELVAWLIEKHLVMSTVAQSRDLSDRKTIENFAAVVETVEQMKMLTILTTADIRGVGPGVWNGWKAQLIRTLYYETEPVLTGGFSEVNRAERIRAAQAEFRAAFTEWPEADLNAYVARHYPAYWLKVDLQRKIRHARFLRASEQAGHKLAINVGFDEARAVTELTILAVDHPWLLSVIAGACASAGANIVDAQIYTTTDGRALDTISISREYDRDEDEGRRATRIGETIEEVLEGKLRLPEAVARRASSGSKAKLRAFVVEPEVEINNNWSDRYTVIEVSGLDRPGLLYQLTTAISKLNLNIASAHVATFGERARDVFYVTDLLGAQITAPTRQAAIKRALVHLLANGDAAEKPAA
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: PFD4_AVEFA
Sequence: MQQGDGTEAQVTWEDQQNINRFGRLNNRFHELTDEIRLAKEANENLEDAGNELILCDEDVVRFQIGEVFAHMPMDDVEARLEQMKEDAAKKLERLEEEKESILAQMAELKKILYGKFKDAINLEED
What is the function of this protein?
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it.  Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity).
What are the official names of this protein?
Probable prefoldin subunit 4, VIP3 protein.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit beta family.
Protein: RS15_STAA8
Sequence: MAISQERKNEIIKEYRVHETDTGSPEVQIAVLTAEINAVNEHLRTHKKDHHSRRGLLKMVGRRRHLLNYLRSKDIQRYRELIKSLGIRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: RLUC_RICPR
Sequence: MIIDVNIPIPFRLDKYLKRLYPLLTQGVIEKALRQKQITVNFQKAEANLRVKVGDTIFINDYFNLPVTQHETLVFADAEIKLAKKILTDYLIYEDDHLIAINKPASLATQGGSKINLSIDSALKYLNYQGADFKLVHRLDKETSGLLLIAKNYLSSVKLHNAFKEKLVIKKYFAITYGRPVKNVGTVKSNIGKSKRRLSKIANIDSDDGKLAITYYKLLKSLNNNLFLIEFMPVTGRMHQLRLHAQLLGCPILGDDKYGNKEIMPYSKYMFLHANNIYLSETIVGKEIKLEAKLPFYFTRRII
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil at positions 955, 2504 and 2580 in 23S ribosomal RNA.
What are the official names of this protein?
Ribosomal large subunit pseudouridine synthase C, 23S rRNA pseudouridine(955/2504/2580) synthase, rRNA pseudouridylate synthase C, rRNA-uridine isomerase C.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RluA family.
Protein: HRCA_AFIC5
Sequence: MSHHDPKEALITPGAALSQLNERSRDIFRQIVENYLATGEPVGSRNISRMISVPLSPASVRNVMADLEQLGLIYAPHTSAGRLPTELGLRFFVDALMQVGDLTEDERQSIQAQLAAIGKQQSIEATLSDAMMRLSGLTRAAAVVLTGKSNPRLKHIEFVRLEPEQALVVLVSEDGQIENRVLALPPGVPSSALIEASNFLNSRIRGRTLSEVRGELEAALAQRRSELDQLTQKIIAAGVASWSGGSSDERRLIVRGHANLLEDLHAMEDLERVRLLFDDLETKKGVADLLGLAEQGEGVRIFIGSENKLFSLSGSSTITAPYRDSSGRIVGVLGVIGPTRLNYARVIPMVDYAARIVSQMLGK
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: MALK_SALTY
Sequence: MASVQLRNVTKAWGDVVVSKDINLDIHDGEFVVFVGPSGCGKSTLLRMIAGLETITSGDLFIGETRMNDIPPAERGVGMVFQSYALYPHLSVAENMSFGLKLAGAKKEVMNQRVNQVAEVLQLAHLLERKPKALSGGQRQRVAIGRTLVAEPRVFLLDEPLSNLDAALRVQMRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKPLELYHYPADRFVAGFIGSPKMNFLPVKVTATAIEQVQVELPNRQQIWLPVESRGVQVGANMSLGIRPEHLLPSDIADVTLEGEVQVVEQLGHETQIHIQIPAIRQNLVYRQNDVVLVEEGATFAIGLPPERCHLFREDGSACRRLHQEPGV
What is the function of this protein?
Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Maltose/maltodextrin import ATP-binding protein MalK.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Maltooligosaccharide importer (TC 3.A.1.1.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PADC1_MOUSE
Sequence: MSRGAAGWCCLVLWLPTCVAAHGLRIHDYLYFQVLSPGDIRYIFTATPAKDFGGIFHTRYEQIHLVPAEPPEACGELSNGFFIQDQIALVERGGCSFLSKTRVVQEHGGRAVIISDNAVDNDSFYVEMIQDSTQRTADIPALFLLGRDGYMIRRSLEQHGLPWAIISIPVNVTSIPTFELLQPPWTFW
What is the function of this protein?
Plays a role in the modulation of physical activity and adiposity.
What are the official names of this protein?
Protease-associated domain-containing protein 1, Protease-associated domain-containing protein of 21 kDa.
What are the subcellular locations of this protein?
Secreted.