PharMolix/UniProtQA huggingface dataset:
Protein: AT2C2_MOUSE
Sequence: MGRRLKFLQKLAFLGQNHRYKALERDEVETLIDEQCELKAIEREKTVAALPPGEACKCSREELARAFHVDLDSGLSEFAVAQRRLVHGWNEFVTDNAEPVWKKYLDQFRNPLILLLLGSSVVSVLTKEYEDAVSIALAVLIVVTVGFIQEYRSEKSLEELTKLVPPECNCLRDGKLRHMLARDLVPGDIVSLSMGDRIPADIRLTEVTDLLVDESSFTGEVEPCGKTDSPLADGGDLSTLSNVVFMGTLVQCGKGQGVVIGTGEQSQFGEVFKMMRAEETPKTPLQKSMDKLGKQLTIFSFGIIGLLMLVGWVQGKPFLSMFTVGVSLAVAAIPEGLPIVVMVTLVLGVLRMAKKRVIVKKLPIVETLGCCNVICSDKTGTLTANEMTATQLVTSDGFHAEVSGVGYSGEGTVCLLPSKEVIKGFDNVSVGKLVEAGCVANNAVIRKNAVMGQPTEGALVVLAMKMNLGSIKDSYVRKKEIPFSSEQKWMAVRCGPKSEDGEDIYFMKGAFEEVIHHCSMYNNGGIPLPLTPQQKSYCQQEEKKMGSLGLRVLALASGPELGRLTFLGLVGIIDPPRAGVKEAVQVLSESGVSVKMVTGDALETALAIGRTIGLCNEKLKAMSGEEVEGTEQGALAARVRQVSVFFRTSPKHKVKIIKALQESGAIVAMTGDGVNDSVALKSADIGIAMGQTGTDVSKEAANMILVDDDFSAIMSAVEEGKGIFYNIKNFVRFQLSTSIAALSLITLSTVCNLPSPLNAMQILWVNIIMDGPPAQSLGVEPVDRDALRRPPRSVGDTILNRALILRVLMSAAVIIGGTLFIFWREIPANGTSTPRTTTMAFTCFVFFDLFNALSCRSQTKLIFEIGFFRNRMFLYSVLGSLLGQLAVIYAPPLQKVFQTENLSALDLLLLTGLASSVFILSELLKLWEKFLSRARPTQMLPEAV
What is the function of this protein?
ATP-driven pump that supplies the Golgi apparatus with Ca(2+) and Mn(2+) ions, both essential cofactors for processing and trafficking of newly synthesized proteins in the secretory pathway.  Within a catalytic cycle, acquires Ca(2+) or Mn(2+) ions on the cytoplasmic side of the membrane and delivers them to the lumenal side.  The transfer of ions across the membrane is coupled to ATP hydrolysis and is associated with a transient phosphorylation that shifts the pump conformation from inward-facing to outward-facing state (By similarity).  Induces Ca(2+) influx independently of its ATP-driven pump function.  At the basolateral membrane of mammary epithelial cells, interacts with Ca(2+) channel ORAI1 and mediates Ca(2+) entry independently of the Ca(2+) content of endoplasmic reticulum or Golgi stores.  May facilitate transepithelial transport of large quantities of Ca(2+) for milk secretion via activation of Ca(2+) influx channels at the plasma membrane and active Ca(2+) transport at the Golgi apparatus (PubMed:23840669) (By similarity).
What are the official names of this protein?
Calcium-transporting ATPase type 2C member 2, ATPase 2C2, Ca(2+)/Mn(2+)-ATPase 2C2, Secretory pathway Ca(2+)-transporting ATPase type 2, SPCA2.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein.
Protein: RLA2_BOVIN
Sequence: MRYVASYLLAALGGNSSPSAKDIKKILDSVGIEADDDRLNKVISELHGKNIEDVIAQGIGKLASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEKKEEKKEESEESDDDMGFGLFD
What is the function of this protein?
Plays an important role in the elongation step of protein synthesis.
What are the official names of this protein?
60S acidic ribosomal protein P2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein P1/P2 family.
Protein: MATK_GAUPR
Sequence: MEEFKRYLELDRXQQHDFIYPLIFQEYIYALAHDRGLNKSIFFENADYDNKSSLLIVKRLITHLITQMYQQNHFFFYTNDFNPNKFLGYNTNLYSQMIFEGFVVVVEIPFYLRLLSFLEGKDREXLIXLXSLHSIFPFLEDKFSHLNYILDILIPHPVHLEILXQTLRYWVKDPSSLHLLXFFLHEYSNWNSLITPKKYSSSFSKRNQKFFLFLYNFHVCEYESIFVFLRNQSSHLCSISFETFLERILFYKKIELEIFVKDFKAILWVFKDPLLHYVRYRGKSILASKGSSLLMDKWKYYVVNFWECYFYIWAQPRRIHINQLSNNSLDFLGYLSSIRLKPSMVRSQMIENSFLIENASKKFDTLVPITPMIESLSKAKFCNVLGQPMSKPVWGGLSDSDIIERFGRIYRNLSHYYSGSLKKITLYRIKYILRLSCARTLARKHKSTVRSFLKRLGVGLLEEFFTEEEQVFYLTFPKASSTSRKLYQRRIWYLDIFCINDTANHE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RM23_SCHPO
Sequence: MSTLNGQTALAYAKVWHHVSAKNVPLGRLASQIATTLMGKHKPIYHPAADCGDVVVVTDCSEIGISGRKLENHKYYSHSGQPGHLKEWTMEEMAAKRGHKDLLRRAVGGMLPRNKLWDRRMKRLYIYDGAEHPYKANIFRSYHNPVSSQIAKELFSK
What are the official names of this protein?
54S ribosomal protein L23, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: MEI1_HUMAN
Sequence: MAVRQAATAGTPGPRREEEAALLFERAHYRHDPRWLLPVTPRLCLACALELLPDPGVSLVRKKHMLSCFQDALVRHTSLVTQLVSQDQRVCIHFISVLFGLLCSMEDGSVTDLCIEVLIQITTQLKLEQTIRCLLDECHKELCNMPSMRGSLATLTLLGKLVDAIPALADELVMEHGNLMEHLLRGLVYPSEGIQASVCYLYGKLYSSPVAAEMLSGHFREKLFPLFLSILDGAQTKELQINCLGLLRQLLKYDLFVSMIMNQDGLGESAKNIEGSSGNTSLPLVLKKLLLSRDETLQVASAHCITAVLVHSPAKHASAFIHADIPEFLFEHLSSSSEVLVWSSCNCLTLLVEEPLFFSKCHTVYGIEAVVRSLQGSLKMNNIELHKQGLLLFAEILTRQPEEIKLFTSSAMCRDAGRALQEAVSSPVLEVAAEALKATSAFLRKDHQSTPPVQYGELQALLEAMLNRCAEFSQTLLSRRPLGHASSRDSEKAILQRGKFLLSTLEGFRSACRLAIEFQSEPSAQENPFTAPSAKKEDTLEAFSEFLLSACDSLCIPMVMRHLEQTTHPALMEVFLSILHNLFVIVPHMKEKFSKKLASSSFIRLTLELKARFCSGLSHSALNQVCSNFLYYMCLNLLSAPEKTGPPSKEELSAVSELLQHGLPQISSRSPESLAFLSDRQYMEGAARQRQYCILLLFYLAYIHEDRFVSEAELFEAVQSFLLSLQDQGERPPLVVFKASIYLLAICQDKDNTLRETMVSAIRKFLEGIPDLQLVYTHHPLLLRFFLLYPELMSRYGHRVLELWFFWEESSYEELDDVTSAGQPALPASLVVLFQLLRSIPSILLILLDLIYSSPVDTAHKVLISLRTFLRRNEDIQVGGLIRGHFLLILQRLLVEHGASPSGASGNLPLLLSLLSLMQLRNVSEQELDSVAMKLLHQVSKLCGKCSPTDVDILQPSFNFLYWSLHQTTPSSQKRAAAVLLSSTGLMELLEKMLALTLAKADSPRTALLCSAWLLTASFSAQQHKGSLQVHQTLSVEMDQVLKALSFPKKKAALLSAAILCFLRTALRQSFSSALVALVPSGAQPLPATKDTVLAPLRMSQVRSLVIGLQNLLVQKDPLLSQACVGCLEALLDYLDARSPDIALHVASQPWNRFLLFTLLDAGENSFLRPEILRLMTLFMRYRSSSVLSHEEVGDVLQGVALADLSTLSNTTLQALHGFFQQLQSMGHLADHSMAQTLQASLEGLPPSTSSGQPPLQDMLCLGGVAVSLSHIRN
What is the function of this protein?
Required for normal meiotic chromosome synapsis.  May be involved in the formation of meiotic double-strand breaks (DSBs) in spermatocytes (By similarity).
What are the official names of this protein?
Meiosis inhibitor protein 1, Meiosis defective protein 1.
Protein: DABA_IDILO
Sequence: MSTANRLATIAGQVSKAIAPQWPLSQWIAVNPFWHYRQQPVAGVAAHWRYSAGTRLLMSPDFYWQQWQQNRIDAALVTNKMVNELEQRSLLKAQLPQWRNLSRLVDKYTRRRRKMRWNDEVVLQISQTCGLFMQFPTRFQQAGKDSSLYQHWLTISRADRGIETLMDEAELTELFAQLPDDPHKLIQVCHDNFLSDASDYALRCYSQALISDLWGWAAAFSYQDARQDSQWVFELLCIRLAWEYILWQLAERTNTKVYQQLQQALSAQVENCEGQVAHIEQHNSLLWQWQAAYERSQLNRLQFKSDTVEESNAPDVQAVFCIDVRSERYRRALEQAGKSLGSYVQSKGFAGFFGVPLAIQRKGRDVPHVPGLLQPAYYIKAPARKQSVGSLLSNMFNAPVSMFSGVEALGLSKLKSLLTGVPGQLATANNAYIADGSICEHNGEASMESLVGICQQALAGMQFTRFARHIVLVGHGSHHSNNAQRAGLNCGACGGQTGALSARVLVRLLNNQNIREHLREQGVAIPDATQFHSAMHETVTDKVIWLSNTVPDSVKQVFRAATEKLTQACGESEKDRKTRSGHWAELRPEWGLADNNVLFFGQADRLTSADTIGSNFLHDYNSINDPDGELLAQLMSAPGLVANWINWQYYCSVTEPKQLGSGNKLLHNRVANDIGVFEGNGGDLRQGLAWQSVHNGSDFVHRPMRLQVIVEADEATIQRALAKAVAFNELFEQQWINLHRLNARGELCPVTTPVTAK
What is the function of this protein?
Part of an energy-coupled inorganic carbon pump.
What are the official names of this protein?
Probable inorganic carbon transporter subunit DabA.
What is the protein family that this protein belongs to?
Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MTSS1_HUMAN
Sequence: MEAVIEKECSALGGLFQTIISDMKGSYPVWEDFINKAGKLQSQLRTTVVAAAAFLDAFQKVADMATNTRGGTREIGSALTRMCMRHRSIEAKLRQFSSALIDCLINPLQEQMEEWKKVANQLDKDHAKEYKKARQEIKKKSSDTLKLQKKAKKGRGDIQPQLDSALQDVNDKYLLLEETEKQAVRKALIEERGRFCTFISMLRPVIEEEISMLGEITHLQTISEDLKSLTMDPHKLPSSSEQVILDLKGSDYSWSYQTPPSSPSTTMSRKSSVCSSLNSVNSSDSRSSGSHSHSPSSHYRYRSSNLAQQAPVRLSSVSSHDSGFISQDAFQSKSPSPMPPEAPNQLSNGFSHYSLSSESHVGPTGAGLFPHCLPASRLLPRVTSVHLPDYAHYYTIGPGMFPSSQIPSWKDWAKPGPYDQPLVNTLQRRKEKREPDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELALALSRGLQLDTQRSSRDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEFDKSSTIPRNSDISQSYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVRRGTIGAGPIPIKTPVIPVKTPTVPDLPGVLPAPPDGPEERGEHSPESPSVGEGPQGVTSMPSSMWSGQASVNPPLPGPKPSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPESDPADLSPRDTPQGEDMLNAIRRGVKLKKTTTNDRSAPRFS
What is the function of this protein?
May be related to cancer progression or tumor metastasis in a variety of organ sites, most likely through an interaction with the actin cytoskeleton.
What are the official names of this protein?
Protein MTSS 1, Metastasis suppressor YGL-1, Metastasis suppressor protein 1, Missing in metastasis protein.
What is the protein family that this protein belongs to?
Belongs to the MTSS family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: CBX5_MOUSE
Sequence: MGKKTKRTADSSSSEDEEEYVVEKVLDRRMVKGQVEYLLKWKGFSEEHNTWEPEKNLDCPELISEFMKKYKKMKEGENNKPREKSEGNKRKSSFSNSADDIKSKKKREQSNDIARGFERGLEPEKIIGATDSCGDLMFLMKWKDTDEADLVLAKEANVKCPQIVIAFYEERLTWHAYPEDAENKEKESAKS
What is the function of this protein?
Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression.  In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph).  Can interact with lamin-B receptor (LBR).  This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane.  Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins (By similarity).
What are the official names of this protein?
Chromobox protein homolog 5, Heterochromatin protein 1 homolog alpha, HP1 alpha.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Chromosome, centromere. Note=Colocalizes with HNRNPU in the nucleus (By similarity). Component of centromeric and pericentromeric heterochromatin. Associates with chromosomes during mitosis. Associates specifically with chromatin during metaphase and anaphase.
Protein: ADH_DROHA
Sequence: MVIANSNIIFVAGLGGIGLDTSREIVKSGPKNLVLLDRIDNPAAIAELKALNPKVTVTFYPYDVTVPLAETKKLLKTIFDKLKTVDLLINGAGILDDNQIERTIAVNFTGLVNTTTAILDFWDKRKGGPVGVVANICSVTGFNSIYQVPVYSASKAAALSFTTSIAKLAHITGVTAYSINPGITKTVLEHSFNSWLNVEPRVAELLLEHPTQTTLQCAQNFVKAIEANQNGAIWKLDLGRLDAIEWTKRWDSGI
What are the official names of this protein?
Alcohol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: MDH_THETK
Sequence: MITVVGSGRVGATTAAMLGVLGVDNKIVLIDIIKGLPQGEALDLNHMSSILGLDVYYTGSNDYADMKGSDLVIVTAGLARKPGMTREQLLEQNAQIVANIGKEIAKYAPDSVVILTTNPLDAMTYVMWRATGFSRERVVGFSGVLDGGRLAFYAGQKLGISPASIIPIVLGQHGESMFPVPSKSFVFGVPLDKLLKPEEIKEAVEETVKAGARITELRGFSSNWAPGAGVAIMAKAVKRDERRALIASVVLDGEYGVRGIPVEVPVVLGRGGAIKVLEVELSPEEKQRFQQSVEAISKLLNSLPAQYK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily.
Protein: Y886_CHLCH
Sequence: MRKKRAGRPQHCRCVQDLPKVTCFTPSGVAPEAVEQVLMTVDELEAMRLADRDGLYHADAAMQMKVSRPTFGRILESGRRKVADALVGGKQICIKGGTVLAVCDSIPTERPDICLCPTCGREFPHIKGVPCRNSICPDCNEPLQRKGGCLSDEESDEQENEQRTVGYPESEEELEIE
What are the official names of this protein?
UPF0251 protein Cag_0886.
What is the protein family that this protein belongs to?
Belongs to the UPF0251 family.
Protein: NPR11_CAEEL
Sequence: MGSVNESCDNYVEIFNKINYFFRDDQVINGTEYSPKEFGYFITFAYMLIILFGAIGNFLTIIVVILNPAMRTTRNFFILNLALSDFFVCIVTAPTTLYTVLYMFWPFSRTLCKIAGSLQGFNIFLSTFSIASIAVDRYVLIIFPTKRERQQNLSFCFFIMIWVISLILAVPLLQASDLTPVFVEPSCDLALYICHEQNEIWEKMIISKGTYTLAVLITQYAFPLFSLVFAYSRIAHRMKLRFANRNQNVTTNTNTSQRRRSVVERQRRTHLLLVCVVAVFAVAWLPLNVFHIFNTFELVNSFSVTTFSICHCLAMCSACLNPLIYAFFNHNFRIEFMHLFDRVGLRSLRVVIFGEQESLKKSMRTEFRSRGGCKTVTTAEPATFQRMNESMILSAMEQDEQL
What is the function of this protein?
Could be a receptor for neuropeptide Y and peptide YY.
What are the official names of this protein?
Putative neuropeptide Y receptor 11, NPY-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PEPQ_SALSV
Sequence: MESLAALYKNHIVTLQERTRDVLARFKLDALLIHSGELFNVFLDDHPYPFKVNPQFKAWVPVTQVPNCWLLVDGVNKPKLWFYLPVDYWHNVEPLPTSFWTEEVEVVALPKADGIGSQLPAARGNIGYIGPVPERALQLDIAASNINPKGVIDYLHYYRAYKTDYELACMREAQKMAVSGHRAAEEAFRSGMSEFDINLAYLTATGHRDTDVPYSNIVALNEHAAVLHYTKLDHQAPSEMRSFLLDAGAEYNGYAADLTRTWSAKSDNDYAHLVKDVNDEQLALIATMKAGVSYVDYHIQFHQRIAKLLRKHQIITDMSEEAMVENDLTGPFMPHGIGHPLGLQVHDVAGFMQDDSGTHLAAPSKYPYLRCTRVLQPRMVLTIEPGIYFIESLLAPWREGPFSKHFNWQKIEALKPFGGIRIEDNVVIHENGVENMTRDLKLA
What is the function of this protein?
Splits dipeptides with a prolyl residue in the C-terminal position.
What are the official names of this protein?
Xaa-Pro dipeptidase, X-Pro dipeptidase, Imidodipeptidase, Proline dipeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
Protein: NUOK2_SYMTH
Sequence: MELPIYYPLGLGALLFGLGLWGALTQKNAVRILMFIEIMLNGVNLNLITFSRYYWQTSPEMAARAPILTLFVMTVAAAEASVGLAIILAMVRNRGVVEVDKATLLKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K 2, NADH dehydrogenase I subunit K 2, NDH-1 subunit K 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GPMI_SYNC1
Sequence: MTVEIRRPVALVILDGWGINPVCEHNAVCQADTPRLRALLESWPHARIGASGRDVGLPDGQMGNSEVGHLNIGAGRTVYQDLTRISLSIEEDTFFENTELRKVMQQVVESQGKLHLMGLLSDGGVHSHMEHLYALVEMARRAGVEQVCIHAFMDGRDTPPQSGAGYLAQLEDKLQDIGLGRVATVIGRYWAMDRDNRWERVEKAYRAMTEGVGTSFESSAAAIADAYAQGQTDEFVEPRFVGGEKPCTVDDGDGMIFFNFRADRAREITRTFTSSDFSGFSREKTPRLAGYVCLTEYDASFGLPMAFPPETYPELLGEVVSRAGRKQLRIAETEKYAHVTFFFNGGSEEPFDGEDRVLIPSPKEVATYDLKPEMSAPAVTDAMLERVASGRYDLIVLNFANPDMVGHTGVESAAIAAMETVDACVGRVVDAVLNAGGSLLITADHGNCEQMADAKGAPHTAHTSNPVPVILVDPDRTGVKLRNGILADLAPTLLELMGIDKPAAMTGRSLLEPS
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: GSPK_ECOLI
Sequence: MNNEQRGVALLIVLMLLALMAALAADMTLSFHSQLQRTRQVNHHLQRQYDIELAEKLALASLTQDVKDNDRQTTLQQYWAQPQQLQLEDGNTVKWQLRDAQHCFNLNALAKISDDPLASPDFPAQVFSALLINAGIDRGNTDEIVQSIADYIDVDDSPRFHGAEDSFYQSQTPPRHSANQMLFLTGELRQIKGITENIYQRLIPYVCVLPTTELSINLNMLTENDIPLFRALFLNNITDADARVLLQKRPREGWLTTDAFLYWAQQDFSGVKPLVAQVKRHLFPYSRYFTLSTESISDEQSQGWQSHIFFNRKQQSAQIYRRTLQLY
What is the function of this protein?
Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.  Plays a role in pseudopilus assembly and seems to control its length.  Interacts with the pseudopilus tip complex that is critical for the recognition and binding of secretion substrates.
What are the official names of this protein?
Putative type II secretion system protein K, T2SS protein K, Putative general secretion pathway protein K.
What is the protein family that this protein belongs to?
Belongs to the GSP K family.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: PUR5_CLOBM
Sequence: MVSYKEAGVNIEEGYKSVDLIKKHASKTFTKGVLNNLGSFAGMFELPKYKNPVLVSGTDGVGTKLDIAFRMKKYNTVGIDCVAMCVNDILCHGAKPLFFLDYIACGKLEAEVAAQLVEGVSNGCIQSECALIGGETAEMPGFYRDGEYDIAGFAVGIAEKDEIIDGSKIEDGDILIGIASSGPHSNGYSLIRKLVEDLHKDFAGDKIGNTLLAPTKIYVKPVMKLLEKYNIKGMAHVTGGGFYENIPRMFKDDFTAVINKKSYPIPNIFNHLMSLGVEENHMYNTFNMGIGFVLCVNEKDGENIIKDLIEMGEKGYKIGYVKKGDKSVELI
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSRA_PHOLL
Sequence: MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHREEIYQRIQAEKSQPTTY
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYPH_CHESB
Sequence: MTALVSPAGPEQPSLRVRRLLLHTQHQPVVVMHTDCHVCRSEGLAARSQVLLTNGARQVHATLFQVDGDAVLSHDEVGLSETAWDLLGVAEGDEVRVSHPPALESLASVRRRIYGHRLDAQALSEIVRDVAAGRYTDVHLAAFLTASAALPLDENETADLTGAMIAVGDRMEWDAPTVVDKHCVGGLPGNRTTPIVVAIVAANGLVMPKTSSRAITSPAGTADTMETLAPVDLDLATLRRVVEAEGGCIAWGGAVHLSPADDIFVRVERELDVDTEGQLIASVLSKKISAGSTHVVIDIPVGPTAKVRGEDAASHLASRITAVASRFGLAATCVQTDGSQPVGRGIGPALEAFDVLAVLQNASDAPDDLRRRAATLAGAALEIGRKAGKGEGTALALETLADGRAWKKFEAICEAQGGLRAPPRAAHVHPLVAPRAGRVVHINNRKLSRLAKLAGAPESKAGGVHMDVRLGDEIDRGQPLLHVHAETTGELAYALDYAARAGDIVEIEA
What are the official names of this protein?
Putative thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.
Protein: QUEC_BURM1
Sequence: MIRTDAKDGALVLFSGGQDSATCVAWALERYQTVETLGFDYGQRHRVELECREGVREALKRQFPAWADRLGDDHMIDLSVLGAISDTAMTRAIEIETAANGLPNTFVPGRNLLFMTIAAAIAYRRGLRVLVGGMCETDFSGYPDCRDDTMKALQVALNLGMDTRIVLETPLMWLDKAQTWQLAEQLGGQALVELIRVETHTCYVGERAELHDWGFGCGECPACKLRKRGYEAYLKGERVTEAPL
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: NS12_CVBLU
Sequence: MDIWKPEIKYLRYTNGFNVSELEDACFKFNYKFPKVGYCRVPSHAWCRNQGSFCATLTLYGKSKHYDKYFGVITGFTAFANTVEEAVNKLVFLAVDFITWRRQELNVHG
What are the official names of this protein?
Non-structural protein of 12.7 kDa, ns12.7, 12.7 kDa accessory protein.
What is the protein family that this protein belongs to?
Belongs to the coronaviruses ns12.7 protein family.
Protein: MTF1_YEAST
Sequence: MSVPIPGIKDISKLKFFYGFKYLWNPTVYNKIFDKLDLTKTYKHPEELKVLDLYPGVGIQSAIFYNKYCPRQYSLLEKRSSLYKFLNAKFEGSPLQILKRDPYDWSTYSNLIDEERIFVPEVQSSDHINDKFLTVANVTGEGSEGLIMQWLSCIGNKNWLYRFGKVKMLLWMPSTTARKLLARPGMHSRSKCSVVREAFTDTKLIAISDANELKGFDSQCIEEWDPILFSAAEIWPTKGKPIALVEMDPIDFDFDVDNWDYVTRHLMILKRTPLNTVMDSLGHGGQQYFNSRITDKDLLKKCPIDLTNDEFIYLTKLFMEWPFKPDILMDFVDMYQTEHSG
What is the function of this protein?
Mitochondrial transcription factor that confers selective promoter recognition on the core subunit of the yeast mitochondrial RNA polymerase.  Interacts with DNA in a non-specific manner.
What are the official names of this protein?
Mitochondrial transcription factor 1, Mitochondrial transcription factor mtTFB, Mitochondrial-specificity factor, RF1023.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space.
Protein: SERC1_MOUSE
Sequence: MGSVLGLCSVASWIPCLCGSAPCLLCRCCPSGNNSTVTRLIYALFLLVGVCVACVMLIPGMEEQLNKIPGFCENEKGVVPCNILVGYKAVYRLCFGLAMFYLLLSLLMIKVKSSSDPRAAVHNGFWFFKFATAVAIIIGAFFIPEGTFTTVWFYVGMAGAFCFILIQLVLLIDFAHSWNESWVEKMEEGNSRCWYAALLSATALNYLLSLVAVVLFFVYYTHPASCAENKAFISVNMLLCIGASVMSILPKIQESQPRSGLLQSSVITVYTMYLTWSAMTNEPETNCNPSLLSIIGFNTTRPIPKDGQSVQWWHPQGIIGLVLFLLCVFYSSIRTSNNSQVNKLTLTSDESTLIEDGNGRSDGSLDDGDGIHRAVDNERDGVTYSYSFFHFMLFLASLYIMMTLTNWYRYEPSREMKSQWTAVWVKISSSWIGLVLYVWTLVAPLVLTNRDFD
What is the function of this protein?
Enhances the incorporation of serine into phosphatidylserine and sphingolipids.
What are the official names of this protein?
Serine incorporator 1, Axotomy-induced glyco/Golgi protein 2, Membrane protein TMS-2, Tumor differentially expressed protein 1-like, Tumor differentially expressed protein 2.
What is the protein family that this protein belongs to?
Belongs to the TDE1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RS14_NOCFA
Sequence: MAKKSKVARNEQRKQIVARYAARRAELKELIRKPSTPEADRAAAQAALQRLPRDASPVRLRNRDAADGRPRGHLRKFGLSRVRVREMAHRGELPGVHKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: BIOD_ANOFW
Sequence: MKGFFITGTDTDVGKTFVTACMLRTLVDKRIRATAYKPVQSGAQWREGKWIAPDVDVYRKVIDVTDEDGCTYLLQTPCSPHLAAKIDGVTIEPDHIVAHVHQLQQTYDFVLVEGAGGIAVPLVDDSFLIAHLAQLLHFPLIIVARASVGTINHTVLTVEYAKAFGLQIAGIIMNGFSTPKNEIEQENIRMIEEMTHVPVIGEIPHMTNFSHQQIVWRKEWWQ
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXH_PSEPK
Sequence: MILLISDLHLQEERPDISRAFLDLLDGRARHAKALYILGDFFEAWIGDDAMTPFQQSICQAMRRLSDSGTAIYLMHGNRDFLIGQAFCKAAGCTLLNDPSVIELGGEQVLLMHGDTLCTRDLGYMKMRRLLRNPLSLWILRHLPLSARYKLARKLRSESRTQVRMKSTEIVDVTPEEVPKVMAAHGVRTLVHGHTHRPAIHKLMVDGQPARRIVLGDWDRRGWALQVDEQGFQLAPFEFS
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SECE_VIBCH
Sequence: MKANNAEAPDSSNAADTLKWVATFVLLVAAVVGNYLYGELSVVARAAGVIVLIAAALGVAATTTKGKEAIVFARESRMEVRKVVWPTRQETMQTTLIVLAVSIVMALALWGIDGIMVRLVAFATGV
What is the function of this protein?
Essential subunit of the Sec protein translocation channel SecYEG.  Clamps together the 2 halves of SecY.  May contact the channel plug during translocation.
What are the official names of this protein?
Protein translocase subunit SecE.
What is the protein family that this protein belongs to?
Belongs to the SecE/SEC61-gamma family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.