PharMolix/UniProtQA huggingface dataset:
Protein: BDNF_CYLRU
Sequence: PMKEVSIRGQGSLAYPGLRTQGNLETLNGPNDATRGLTSLADTFEHVIEELLDEQQVIQPSKENKDADLYSSRVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSDPARRGELSVCDSTSEWVTAAEKKTAVDMSGATVTVLEKVPVPKGQLKQYFYETKCSSKGYAKEGCRGIDKRYWNSQCRTTQSYVRALTMDNKKRVGWRFIRIDTS
What is the function of this protein?
Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it.
What are the official names of this protein?
Brain-derived neurotrophic factor, BDNF.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: EIF3J_DROSE
Sequence: MADDWESAADSDVVIRPTAAASVNKWEGEDEDEDIKDSWEDEEEKKDEEKPTKTEAPAKPKPNKALKAKLEQQALREEEAEAERLANLSPAEKLAEKLRLQKIQEASDLKHAQEAFGVTSTCGGLDAFNPETKEEFKEFGATLSWKVAQFRESEHFPQFVEDLVRSLCVNLSAADIKKVKMNVEVLHSEKLKLEKANAKKPAGKGKGKVTLRTENDDIDGYQKYGNDFTEDYDDFM
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit J, eIF3j.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit J family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLSA_METEP
Sequence: MPDLDSIVKDIAAEMRARPDRGAVASYIPELARVDAQGFGLVVIDGEGRVAAGGDADTPFSIQSISKVFTLTLALGMVGDRLWRRVGREPSGSPFNSIVQLEREHGIPRNPFINAGAIAVTDLILSGHQPREALGEILRFMQFVAQDDSITIDERVAASEKRTGFRNAALANYMRSFDVIENPVDYTLGVYFHHCAIAMTCRQLATAGLFLAYSGHHPLAGHSVISAERARRINAIMLTCGHYDGSGDFAYRVGLPGKSGVGGGILAVAPGKASICVWSPGLDAAGNSHLGRIALEMLVKRTGWSIFGV
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: PSAJ_SPIOL
Sequence: MRDFKTYLSVAPVLSTLWFGSLAGLLIEINRFFPDALTFPFFSF
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX, PSI-J.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: KDSA_CHLCV
Sequence: MFSDKMILIAGPCVIEEEETTLEIASRIQELVTPYADRIHWIFKSSYDKANRSSINSYRGPGLNEGLRILSKVKDTLGVEILTDVHSPEEARAAAKVCDILQIPAFLCRQTDLLVAAAETNAVINIKKGQFLSPWDMQGPVDKVLSTGNNKIILTERGCSFGYNNLVSDMRSIPVLSGMGFPVVFDGTHSVQLPGGLKTHSGGQTEFIPTLTRAALAAGAHGLFIETHANPAIAKSDAASMLSLKTFEALLPLWDQLYTCVRSFEMASV
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPPRS_MYCTU
Sequence: MSEDVVTQPPANLVAGVVKAIRPRQWVKNVLVLAAPLAALGGGVRYDYVEVLSKVSMAFVVFSLAASAVYLVNDVRDVEADREHPTKRFRPIAAGVVPEWLAYTVAVVLGVTSLAGAWMLTPNLALVMVVYLAMQLAYCFGLKHQAVVEICVVSSAYLIRAIAGGVATKIPLSKWFLLIMAFGSLFMVAGKRYAELHLAERTGAAIRKSLESYTSTYLRFVWTLSATAVVLCYGLWAFERDGYSGSWFAVSMIPFTIAILRYAVDVDGGLAGEPEDIALRDRVLQLLALAWIATVGAAVAFG
What is the function of this protein?
Involved in the biosynthesis of decaprenylphosphoryl arabinose (DPA) a precursor for arabinan synthesis in mycobacterial cell wall biosynthesis.  Catalyzes the transfer of a 5-phosphoribosyl residue from phosphoribose diphosphate (pRpp) to decaprenyl phosphate (DP) to form decaprenylphosphoryl-5-phosphoribose (DPPR).  The enzyme favors polyprenyl phosphate with 50-60 carbon atoms uses C-75 polyprenyl phosphate less efficiently than C-50 or C-60.
What are the official names of this protein?
Decaprenyl-phosphate phosphoribosyltransferase, 5-phospho-alpha-D-ribose-1-diphosphate:decaprenyl-phosphate 5-phosphoribosyltransferase, DPPR synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: SUFS_ECOSM
Sequence: MTFSVDKVRADFPVLSREVNGLPLAYLDSAASAQKPSQVIDAEAEFYRHGYAAVHRGIHTLSAQATEKMENVRKRASLFINARSAEELVFVRGTTEGINLVANSWGNSNVRAGDNIIISQMEHHANIVPWQMLCARVGAELRVIPLNPDGTLQLEMLPNLFDEKTRLLAITHVSNVLGTENPLAEMITLAHQHGAKVLVDGAQAVMHHPVDVQALDCDFYVFSGHKLYGPTGIGILYVKEALLQEMPPWEGGGSMIATVSLSEGTTWTKAPWRFEAGTPNTGGIIGLGAALEYVSALGLNNIAEYEQNLMHYALSQLESVPDLTLYGPQNRLGVIAFNLGKHHAYDVGSFLDNYGIAVRTGHHCAMPLMAYYNVPAMCRASLAMYNTHEEVDRLVTGLQRIHRLLG
What is the function of this protein?
Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules.  Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation.  Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine.  Selenocysteine lyase activity is however unsure in vivo.
What are the official names of this protein?
Cysteine desulfurase, Selenocysteine beta-lyase, SCL, Selenocysteine lyase, Selenocysteine reductase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFB_METHJ
Sequence: MPVVSLPYKYLERLCGIDRKTIIDHLPMIGSDIERILEDQVDVEFFPSRVDLYSTEGVARAMRGFLELETGEEVYPVSPSSITFSVDENLKEVRPYIGSAVIRDIQLDNEAIISLMGVQEALHWVVGRGRAKVAIGVHDLDKVTPPFRYYGAPVTRSFIPLDYDREMTLTEIMEEHPKGRDYSHIVKDKPVMPLIEDANGNVLSFPPIINGELTRVTESSKNLLLDVTGTDERAVMTALRVLCTTLITAGGRCESVTVNGVVMPDLSPALRNINVTSCNKLLGTSFSADEIATILKKMRYGAEKSGDSTVSIRIPCYRADIMHEWDVYEDVAIGAGFGNLEAELPATFATGCEHPIIALASAIRDICSGLGYLEVMPFTLSNEDVMYTRMQREPDPKALHVLHPISEEQTLVRTDLLPLLLDLLRMNKRRELPQRIFHTGDVVSSMQTYQKLALASTHPGADFSEAYATTDALMRELGISYLPAESADPAFIPGRAVDIMVDGKKMGVFGEIHPGVLNKFDIDQPVIGIEIDLHLLFPGQKETKS
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_ACTP7
Sequence: MKIILLGAPGAGKGTQAQFIMNKFGIPQISTGDMFRAAIKEGTELGKQAKALMDEGKLVPDELTVALVKDRIAQPDCANGFLLDGFPRTIPQADALKDSGVKIDLVLEFDVADEVIVERMSGRRVHQPSGRTYHVVYNPPKVEGKDDVTGEDLIIRQDDKPETVLERLAIYHKQTKPLIAYYTAEAEAGNTRYERLDGTKPVEEVSAELAKILG
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPS5_BEAB2
Sequence: MMRPWTILIASSWLSLAAASASASACAAKPSVAAEIASIDHDNCEHGPNSRGCWGDYSINTNYYEQAPDTGVTREYWFVVENITMAPDGYEQHVLAINRSIPGPLIEANWGDEVVIHVTNNMERNGTAIHWHGIRQLNNNAHDGVPGVTQCPIPPGGSYTYRWKAEQYGTSWYHSHFSLQYSVGLQGPMIIHGPATANYDEDLGTVMLQDWSHVSPFAMWWYARVPSGPPSLSNSLINGKNIFRCTDPLDKNCLGTGERSEWHFEKGKRYRMRLVNTGLYSNFRFAIDGHNLTVIANDFVPIEPYTTDNVIISMGQRYDVIVEANAPEDNYWLRAIWQTSCCPNDYANDTLGIIRYDPQSTALPNTTHPALHYPDNCDDEPAEKLVPHVKVDAGPPARTDVFNLYRHTYDMPRGFMWTLNDTYLWIDWSKPTNLLVAENDTTIFPPNYLLYHTPDGPNQWVYIVFNDISERNRSHPMHLHGHDFFLLGTGEGNFTKDSPLQLKNPPRRDTASWPKRGYMVFAYKTDNPGAWLIHCHIAWHSSQGLGMQMLERPGEMTYTEDEDQALHQTCQSWNKFYESPEQYIQEDSGI
What is the function of this protein?
Oxidoreductase; part of the gene cluster that mediates the biosynthesis of the bibenzoquinone oosporein, a metabolite required for fungal virulence that acts by evading host immunity to facilitate fungal multiplication in insects (PubMed:26305932).  The non-reducing polyketide synthase OpS1 produces orsellinic acid by condensing acetyl-CoA with 3 malonyl-CoA units (PubMed:26305932).  Orsellinic acid is then hydroxylated to benzenetriol by the hydroxylase OpS4 (PubMed:26305932).  The intermediate is oxidized either nonenzymatically to 5,5'-dideoxy-oosporein or enzymatically to benzenetetrol by the oxidoreductase OpS7 (PubMed:26305932).  The latter is further dimerized to oosporein by the catalase OpS5 (PubMed:26305932).  OpS6 probably functions en route for protecting cells against oxidative stress by scavenging any leaked free radical form of benzenetetrol by activating the thiol group of glutathione (PubMed:26305932).
What are the official names of this protein?
Oxidoreductase OpS5, Laccase OpS5, Oosporein biosynthesis protein 5.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
Protein: ASSY_BURMS
Sequence: MTTILENLPAGQKVGIAFSGGLDTSAALHWMRIKGAVPYAYTANLGQPDEDDYDAIPKRAIQYGAEGARLIDCRAQLVAEGIAALQCGAFHISTAGVTYFNTTPIGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLVNPDLKIYKPWLDQQFIDELGGRAEMSEFMRQAGFEYKMSAEKAYSTDSNLLGATHEAKDLESLESGIKIVNPIMGVAFWRDDVKIDKEEVTIRFEEGRPVALNGVEYKDAVALLLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGLALLYIAYERLVTGIHNEDTIEQYRENGRRLGRLLYQGRWFDPQAIMLRETAQRWVARAVTGEVTVELRRGNDYSIIGTRSPNLTYQPERLSMEKVQSMFSPRDRIGQLTMRNLDITDTRDKLRIYSQVGLLAAGESSALPKLKEDESGN
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSRD_KLEP7
Sequence: MKLKLNWESALLALLIAEILLFGALNPRMLDINMLLFSTSDFICIGIVALPLTLVIISGGIDISLGSTIGLCAIALGVMTQAGWPLWLAVSLTLLLGLLCGLFNAALIHYTGINPLVITLGTLYLYGGGALLLSGMAGATGYEGIGGFPDSFTAFANLTLGGLPLPLVLFAIITFFFWLLAHRGRFGRHLFLLGQNPRAARYAALSVNGIPYVLYGLVGVASAVAALVMVSYFGSARSDLGRDLLMPALTAAVLGGANIYGGSGSILGTALAALLVGYLQQGLQMVGIPNQVSSALSGALLVVVVMGRSLSLHREWVRATWRRLFSHKTIGA
What is the function of this protein?
Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import.  Probably responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
Autoinducer 2 import system permease protein LsrD, AI-2 import system permease protein LsrD.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL11_CUTAK
Sequence: MPAKKKVAAVVKVAPQAGQATPAPPVGMALGPHGVNIMEFCKAYNAQTEGQRGNIVPVEITIYEDRTFSFVLKTPPAAELIKKAAGIKKGTENPATHKVGKISKDQVREIAETKMPDLNANDIEAAMKIVAGTARSMGVEVEV
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: NARF_DROPS
Sequence: MSRFSGALQLTDLDDFITPSQECIKPVTVDKTATSKTGAKITVQEDGYYEESESGKQKLQKVEITLQDCLACSGCITSAESVLITQQSEEELLKVLRENAKVKATGDMEQVRTIVFTIATQPLLSLAHRYQLSAEETARHLAGYFRSLGVDYVLCTKVADDLALLECQQEFVERYRDNEELTMLSSSCPGWVCYAEKTHGNFILPYIATTRSPQQIMGVLVKQFLAEKLNIPGSRIYHVTVMPCYDKKLEASRMDFYSEVNESRDVDCVITSVEVEQMLNEDERSLSEHEASDLDWPWSEQRPESMVWSHEATLSGGYAEHIFKFAAKELFNEAPPTELSFKQLRNRDFREISLEKDDKTVLKFAIANGFRNIQNLVQKLKRGKGASYHFVEVMACPSGCINGGAQVRPTTGQHVRELTQQLEELYKKLPRSQPDNAHTKLIYRDFLDGSHTDKSNELLHTSYHAVEKLSTALNIKW
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery.  Required for maturation of extramitochondrial Fe/S proteins (By similarity).
What are the official names of this protein?
Probable cytosolic Fe-S cluster assembly factor GA29080.
What is the protein family that this protein belongs to?
Belongs to the NARF family.
Protein: Y1577_SYNSC
Sequence: MEFLTHSLLPLHEVCALQQRLSAPNLPWRDGRLTAGDQAALVKKNYQLDPNAELSLAISNCISTALTSDPLVKSFSLVRKVHSLLVSRSSAGESYGWHVDNPFSRNGRRDLSFTCFLSDEDSYEGGSLMIQTGGEDTKEFRLPPGQVVLYPSSTLHCVTPVLSGDRYVCVGWIESYVKAADDRSMLFNIDAGARGLLARHGRSDELDLIFQSYTNAVRRLSS
What are the official names of this protein?
PKHD-type hydroxylase Syncc9605_1577.
Protein: PQQE_KLEPN
Sequence: MSQSKPTVNPPLWLLAELTYRCPLQCPYCSNPLDFARQDKELTTEQWIEVFRQARAMGSVQLGFSGGEPLTRKDLPELIRAARDLGFYTNLITSGIGLTESKLDAFSEAGLDHIQISFQASDEVLNAALAGNKKAFQQKLAMAKAVKARDYPMVLNFVLHRHNIDQLDKIIELCIELEADDVELATCQFYGWAFLNREGLLPTREQIARAEQVVADYRQKMAASGNLTNLLFVTPDYYEERPKGCMGGWGSIFLSVTPEGTALPCHSARQLPVAFPSVLEQSLESIWYDSFGFNRYRGYDWMPEPCRSCDEKEKDFGGCRCQAFMLTGSADNADPVCSKSPHHHKILEARREAACSDIKVSQLQFRNRTRSQLIYQTRDL
What is the function of this protein?
Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
What are the official names of this protein?
PqqA peptide cyclase, Coenzyme PQQ synthesis protein E, Pyrroloquinoline quinone biosynthesis protein E.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. PqqE family.
Protein: TAF10_ARATH
Sequence: MNHGQQSGEAKHEDDAALTEFLASLMDYTPTIPDDLVEHYLAKSGFQCPDVRLIRLVAVATQKFVADVASDALQHCKARPAPVVKDKKQQKDKRLVLTMEDLSKALREYGVNVKHPEYFADSPSTGMDPATRDE
What is the function of this protein?
TAFs are components of the transcription factor IID (TFIID) complex that is essential for mediating regulation of RNA polymerase transcription.  Involved in osmotic stress adaptation during the germination stage and in gene expression related to meristem activity and leaf development.
What are the official names of this protein?
Transcription initiation factor TFIID subunit 10, Protein SALT TOLERANCE DURING GERMINATION 1, TBP-associated factor 10, AtTAF10, TBP-associated factor II 15.
What is the protein family that this protein belongs to?
Belongs to the TAF10 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DEF_PEDPA
Sequence: MIKMNDITRDGNPVLRKRAEKLTFPLDPKYLKVADEMMEYLKNSQDPAIAEKYHLRAGVGLAAPQIGLSIQMASVLVPGPDNTIDLEETLVNPVIVSQSVQIAALEEGEGCLSVDKDVPGYVPRHDRITVRYQTLDGEEKTIKLRDYPAIVCQHEIDHLKGTLFYDHINKENPLDIEDNAILIG
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: RL7_STRE4
Sequence: MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAAGGAEEATKDSFDVELTSAGDKKVGVIKAVREITGLGLKEAKGLVDGAPANIKEGVAAAEAEEIKAKLEEAGATITLK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: UBA5_BOVIN
Sequence: MAESVERLQQRVEELERELAQERSRRALGSGDGGGGRARIEKMSSEVVDSNPYSRLMALKRMGIVSDYEKIRTFTVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANMNRLFFQPHQAGLSKVQAAEHTLRNINPDVLFEVHNYNITTVENFEHFMNRISNGGLEEGKPVDLVLSCVDNFEARMTINTACNELGQTWMESGVSENAVSGHIQLIIPGESACFACAPPLVVAANIDEKTLKREGVCAASLPTTMGVVAGILVQNVLKFLLNFGTVSFYLGYNAMQDFFPTMSMKPNPQCDDRNCRKQQKEYKKKVAALPKQEVIQEEGEIIHEDNEWGIELVSEISEEELKKSSGPIPDLPEGIIVAYTVPQKQEDSVPEVTVEDSGESLEDLMAKMKNI
What is the function of this protein?
E1-like enzyme which specifically catalyzes the first step in ufmylation.  Activates UFM1 by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a UFM1-E1 thioester and free AMP.  Activates UFM1 via a trans-binding mechanism, in which UFM1 interacts with distinct sites in both subunits of the UBA5 homodimer.  Trans-binding also promotes stabilization of the UBA5 homodimer, and enhances ATP-binding.  Transfer of UFM1 from UBA5 to the E2-like enzyme UFC1 also takes place using a trans mechanism.  Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress (By similarity).  Ufmylation is essential for erythroid differentiation of both megakaryocytes and erythrocytes (By similarity).
What are the official names of this protein?
Ubiquitin-like modifier-activating enzyme 5, Ubiquitin-activating enzyme 5, UFM1-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-activating E1 family. UBA5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Endoplasmic reticulum membrane. Golgi apparatus. Note=Localizes mainly in the cytoplasm, while it localizes to the nucleus in presence of SUMO2. Interaction with GABARAPL2 promotes localization to the endoplasmic reticulum membrane.
Protein: TRMB_BURVG
Sequence: MMHDDPNEAGLPPDDAALPDEAADGADEVNPLHHRRIRSFVTRAGRVSTGQRRAIDELGPRFVVPYAPTLPDWDAVFGRSAPRILEIGFGMGASTAEIAAHRPGDDFLGVEVHEPGVGALLKLIGEQGLTNIRIIQHDAVEVLEHMLAPESLDGVHIFFPDPWHKARHHKRRLIQPPLVAQLAARLKPGAYLHCATDWQNYAEQMLEVLSAEPTLENTAADYAPRPDYRPVTKFERRGLRLGHGVWDLVFRKRAA
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: DCUR_ECOLI
Sequence: MINVLIIDDDAMVAELNRRYVAQIPGFQCCGTASTLEKAKEIIFNSDTPIDLILLDIYMQKENGLDLLPVLHNARCKSDVIVISSAADAATIKDSLHYGVVDYLIKPFQASRFEEALTGWRQKKMALEKHQYYDQAELDQLIHGSSSNEQDPRRLPKGLTPQTLRTLCQWIDAHQDYEFSTDELANEVNISRVSCRKYLIWLVNCHILFTSIHYGVTGRPVYRYRIQAEHYSLLKQYCQ
What is the function of this protein?
Member of the two-component regulatory system DcuR/DcuS.  Involved in the C4-dicarboxylate-stimulated regulation of the genes encoding the anaerobic fumarate respiratory system (frdABCD; nuoAN; dcuB; dcuC; sdhCDAB; etc. ).  Weakly regulates the aerobic C4-dicarboxylate transporter dctA.
What are the official names of this protein?
Transcriptional regulatory protein DcuR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLH12_FORAG
Sequence: MNSKKTGVIILGCIAFLHIACSGDKKTQAQDTSDSMLEKSSAISEKPNIIFYLADDQDVYDYGCYGNEKVHTPAVDALAKDGILFTNAFTAQAICAPSRSQLFTGKYPLKNGCFANHTGTRSDIKSVTTHMKKLGYEVVLAGKSHVKPENVYQWDREWEPVPKQGVPRDYIPLDSIAAYLKNAKKPFCMFITSKYPHGKYFDVEHPKASDIKFYPFNENKKTDKTFIKTKAGYYRSIEEDNTQLEEVLKLVDTYLTDNTLFIYSADHGVSGKFTVKDIGLKVPFVARWPKVIKPGSTSNQLIHYTDVLPTFMEIAGGKFPEDMDGNSFLPLLQGKDVEVNNYVYGVRTNQNILNSEIFPSRMIRDKRYKYIRNFNSIEVVEQNLTGKPNVNYFIERGAKAHKNEPFEELYDLQNDPFEQHNLASNPDYKSIKEKLIKDMFSWMKAQGDILSENMIGIPIITPKGNRGFKLDQDTPRRKIPEARKNTLTKDDYIVIEHW
What is the function of this protein?
Sulfatase involved in ulvan degradation (PubMed:31285597).  Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall.  It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl) (Probable).
What are the official names of this protein?
Ulvan-active sulfatase, Arylsulfatase, Polysaccharide utilization locus H protein P12, PUL H protein P12, Sulfatase family S1 subfamily 8 protein P12, P12_S1_8.
What is the protein family that this protein belongs to?
Belongs to the sulfatase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: SYDP_ECO45
Sequence: MDDLTAQALKDFTARYCDAWHEEHKSWPLSEELYGVPSPCIISTTEDAVYWQPQPFTGEQNVNAVERAFDIVIQPTIHTFYTTQFAGDMHAQFGDIKLTLLQTWSEDDFRRVQENLIGHLVTQKRLKLPPTLFIATLEEELEVISVCNLSGEVCKETLGTRKRTHLASNLAEFLNQLKPLL
What is the function of this protein?
Interacts with the SecY protein in vivo.  May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.
What are the official names of this protein?
Protein Syd.
What is the protein family that this protein belongs to?
Belongs to the Syd family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Loosely associated with the cytoplasmic side of the inner membrane, probably via SecY.
Protein: CTRO_HUMAN
Sequence: MLKFKYGARNPLDAGAAEPIASRASRLNLFFQGKPPFMTQQQMSPLSREGILDALFVLFEECSQPALMKIKHVSNFVRKYSDTIAELQELQPSAKDFEVRSLVGCGHFAEVQVVREKATGDIYAMKVMKKKALLAQEQVSFFEEERNILSRSTSPWIPQLQYAFQDKNHLYLVMEYQPGGDLLSLLNRYEDQLDENLIQFYLAELILAVHSVHLMGYVHRDIKPENILVDRTGHIKLVDFGSAAKMNSNKMVNAKLPIGTPDYMAPEVLTVMNGDGKGTYGLDCDWWSVGVIAYEMIYGRSPFAEGTSARTFNNIMNFQRFLKFPDDPKVSSDFLDLIQSLLCGQKERLKFEGLCCHPFFSKIDWNNIRNSPPPFVPTLKSDDDTSNFDEPEKNSWVSSSPCQLSPSGFSGEELPFVGFSYSKALGILGRSESVVSGLDSPAKTSSMEKKLLIKSKELQDSQDKCHKMEQEMTRLHRRVSEVEAVLSQKEVELKASETQRSLLEQDLATYITECSSLKRSLEQARMEVSQEDDKALQLLHDIREQSRKLQEIKEQEYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRKATECQHKLLKAKDQGKPEVGEYAKLEKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAERELEKLQNREDSSEGIRKKLVEAEELEEKHREAQVSAQHLEVHLKQKEQHYEEKIKVLDNQIKKDLADKETLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKNRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQRMLDTEKQSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKLETERELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEALDRADLLKTERSDLEYQLENIQVLYSHEKVKMEGTISQQTKLIDFLQAKMDQPAKKKKGLFSRRKEDPALPTQVPLQYNELKLALEKEKARCAELEEALQKTRIELRSAREEAAHRKATDHPHPSTPATARQQIAMSAIVRSPEHQPSAMSLLAPPSSRRKESSTPEEFSRRLKERMHHNIPHRFNVGLNMRATKCAVCLDTVHFGRQASKCLECQVMCHPKCSTCLPATCGLPAEYATHFTEAFCRDKMNSPGLQTKEPSSSLHLEGWMKVPRNNKRGQQGWDRKYIVLEGSKVLIYDNEAREAGQRPVEEFELCLPDGDVSIHGAVGASELANTAKADVPYILKMESHPHTTCWPGRTLYLLAPSFPDKQRWVTALESVVAGGRVSREKAEADAKLLGNSLLKLEGDDRLDMNCTLPFSDQVVLVGTEEGLYALNVLKNSLTHVPGIGAVFQIYIIKDLEKLLMIAGEERALCLVDVKKVKQSLAQSHLPAQPDISPNIFEAVKGCHLFGAGKIENGLCICAAMPSKVVILRYNENLSKYCIRKEIETSEPCSCIHFTNYSILIGTNKFYEIDMKQYTLEEFLDKNDHSLAPAVFAASSNSFPVSIVQVNSAGQREEYLLCFHEFGVFVDSYGRRSRTDDLKWSRLPLAFAYREPYLFVTHFNSLEVIEIQARSSAGTPARAYLDIPNPRYLGPAISSGAIYLASSYQDKLRVICCKGNLVKESGTEHHRGPSTSRSSPNKRGPPTYNEHITKRVASSPAPPEGPSHPREPSTPHRYREGRTELRRDKSPGRPLEREKSPGRMLSTRRERSPGRLFEDSSRGRLPAGAVRTPLSQVNKVWDQSSV
What is the function of this protein?
Plays a role in cytokinesis.  Required for KIF14 localization to the central spindle and midbody.  Putative RHO/RAC effector that binds to the GTP-bound forms of RHO and RAC1.  It probably binds p21 with a tighter specificity in vivo.  Displays serine/threonine protein kinase activity.  Plays an important role in the regulation of cytokinesis and the development of the central nervous system.  Phosphorylates MYL9/MLC2.
What are the official names of this protein?
Citron Rho-interacting kinase, CRIK, Serine/threonine-protein kinase 21.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm.