PharMolix/UniProtQA huggingface dataset:
Protein: G6PI_STRPS
Sequence: MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSDFLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFANLQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFKELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLLPIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEPSLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDKPRKNVIIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAFTLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSGA_CHRSD
Sequence: MSKRKLSRQQRWRVEKIQAERAERAERRARRDDTSLDAGDYGPERLGRVTAHFGRTLEVEAEDEHGDLQRHRCHLRANLEGLVTGDHVVWRVAADGSGVVVARQPRQSVLERPDARGQLKPVAANIAQILIVFAVEPAPHPNLIDRYLVAAEATGITPVLVLNKTDLLPETGSDLRTLLARYRAIGYRVVAASTQQEGGLDALHACLTERTSVFVGQSGVGKSSLIDRLLPDMQLRVGALSADSRKGTHTTTTATLYHLPAGGELIDSPGIREFGLGHLEEHQVAQGFIEFQPYLGHCRFRDCRHRQEPGCALRDAVERGDILASRFDSYRHIVDGLTTR
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGXB_ASPFU
Sequence: MKFFALAALFASTVNSIAVDGLIPGARVIPANDVVALKKAGAYHQKHHHRRTVIIRSSSSDEDDVSADFLWGIKRANHGGRLLLQNGKKYVIGKKLDLTFLKDIEVQLDGELKFTNDVPYWQANNFYYDFQKSISFWRWGGEDIKIFGSGVLNGNGQRWYNEFAGQEILDPNNKYYRPILFVTENATRVSVEGITQLNSPCWTNFFVRTKDISFDNVFIHAYSTNASALPKNTDGFDTLNVDGLTVTNTRVDIGDDCLSPKPNTTNVFVKNLWCNGTHGASMGSIGQYPGVLDIIENVWIENVTLLNGENGARLKAWAGPDVGYGRINNVTYKNIHVENTDNPIVLDQCYFNINATQCAAYPSRVNFTNIVFEDIYGTSSGKRGKVVADLTCSPNAVCSGIRLKNIHLTSPAGSPPVIVCDGIQGDIGVECQSSSNSTTRRSVDLARSLKYRA
What is the function of this protein?
Specific in hydrolyzing the terminal glycosidic bond of polygalacturonic acid and oligogalacturonates.
What are the official names of this protein?
Probable exopolygalacturonase B, Galacturan 1,4-alpha-galacturonidase B, Poly(1,4-alpha-D-galacturonide)galacturonohydrolase B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted.
Protein: CLPS_AERS4
Sequence: MSKQKELFANEEIAQAEKTKLQPPPMYKVVLNNDDYTPMEFVVEVLQKFFGMDLDKATQVMLSVHYSGKGVCGTFTAEIAETKVVQVNTYSRNNEHPLLCTMEKA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: CRCB2_MYCTO
Sequence: MTASTALTVAIWIGVMLIGGIGSVLRFLVDRSVARRLARTFPYGTLTVNITGAALLGFLAGLALPKDAALLAGTGFVGAYTTFSTWMLETQRLGEDRQMVSALANIVVSVVLGLAAALLGQWIAQI
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 2.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PIP13_MAIZE
Sequence: MEGKEEDVRLGANKFSERQPIGTAAQGAGAGDDDKDYKEPPPAPLFEPGELKSWSFYRAGIAEFVATFLFLYITVLTVMGVSKSTSKCATVGIQGIAWSFGGMIFALVYCTAGISGGHINPAVTFGLFLARKLSLTRAIFYIIMQCLGAICGAGVVKGFQQGLYMGNGGGANVVAPGYTKGDGLGAEIVGTFILVYTVFSATDAKRNARDSHVPILAPLPIGFAVFLVHLATIPITGTGINPARSLGAAIIYNRDHAWSDHWIFWVGPFIGAALAAIYHQVIIRAIPFKSRS
What is the function of this protein?
Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
What are the official names of this protein?
Aquaporin PIP1-3/PIP1-4, Plasma membrane intrinsic protein 1-3, Plasma membrane intrinsic protein 1-4, ZmPIP1-3, ZmPIP1-4, ZmPIP1;3, ZmPIP1;4.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family. PIP (TC 1.A.8.11) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATPE_BACAC
Sequence: MKTFPVSIVTPDGPVYEKEVEMVSVKAESGEMGILPGHIPTVAPLKISAVRLKNGGHTDYVAVSGGFIEVRPDKVTVLSSSAEEANHIDIHRANEAKRRAEQRMQDKQAHVDFKRAEMALQRAVNRLNVSDMK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RHLD_GORGO
Sequence: MSSKYPRSVRCCLPLCALTLEAALTLLFYFFTHYDASLEDQKGLVASYQVGQDLTVMAAIGFGFLTSSFRGHSWSSVAFNLFMLALGVQWAILLDGFLSQFPPGKVVITLFSIRLATMSALSVLISAGAVLGYVNLVQLVVMVLVEVTALGTMRMVISNIFNTDYHMNMMHIYVFAACFGLSVAWCLPKPLAKGTEDKDQTATIPSLSAMLGALFLWMFWPSFNSALLRSPIERKNAVFNTYYAVAVSVVTAISVSSLAHPQGKINMTYMHNAVLAGGVAVATSCHLIPSPWLAMVLGLVAGLISIGGAKCLPGCCNRVLGIHDSSVMHYNFSLLGLLGEIIYIVLLVLDTVGAGNGMVGFQVLVSIGELSLAIVIALTSGLLTGLLLNLKIWKAPHAAKYFDDQVFWKFPHLAVGF
What is the function of this protein?
May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane.
What are the official names of this protein?
RH-like protein ID, Rhesus-like protein ID.
What is the protein family that this protein belongs to?
Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: YO10_BPL2
Sequence: MKIKRSEILEQITWQDMMQLLLPEEQIPLMEKDIAKFMSYNHKVPQSVLTAVLMKAIITAKRTHGANTLINEAYLNITFKSFVMDKKKERIIIRTASQAAAKLDKEISDLKQNKIVKPVVTNPDWVDEVMNELVEAFEAQ
What are the official names of this protein?
Uncharacterized 16.1 kDa protein, ORF10.
Protein: MNMG_BACVZ
Sequence: MGYEAGQYDVIVIGAGHAGVEAALASARQGAKTLVLTINLDMVAFMPCNPSVGGPAKGIVVREIDALGGEMARNIDKTHIQMRMLNTGKGPAVRALRAQADKFQYQHEMKHTLEKTPNLTLLQGIAERLIIEDGECRGVITQTGAEYKAKTVVLTTGTYLRGRIILGDLSYSSGPNNQQPSIKLSEHLEELGFDLVRFKTGTPPRVSSDSIDYSKTEIQPGDPVPRAFSYETVEYITDQLPCWLTYTSPETHEIIDSNLHRSPMYSGMIKGTGPRYCPSIEDKVVRFNDKPRHQIFLEPEGRNTQEVYVQGLSTSLPEDVQQRMLATIPGLEKVQMMRAGYAIEYDAIVPTQLWPTLETKKIPNLYTAGQINGTSGYEEAAGQGIMAGINAGRKALGKEEVILSRSDAYIGVLIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLRLTEIGHDIGLISDERYEAFEKKKAAIEAEKKRLWSVIIKPSPENQEYIRSLGGSELKDGVRGTDLMKRPEMNYETVTKLAPADSPVPQDVAEQVEIQVKYEGYIEKSLQQVEKLKKMENKKIPDRIDYDAIKGIATEARQKLKEVRPLSVAQASRISGVNPADISILLVYLEQGRIAKVAE
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GH_GPCMV
Sequence: MSPATRFTVISCLVVSLITPSETSSWFDPFIEWARSSPNMTCVNNRTGTRSLATEGLISFNFYEASRTVRTYQVPKCIFMSSVSKTIMQGVDLFESLESYRRRYYSYIIVPVHASFQIFIHDLRTDLSSPTEELTSPVDKTLPNVTIWHTPSGYVIRLLDVVTPRFEECTLFPNHTVIFDMTVPCSQEVYLRQTGKHQFAIVLTFTPSFFVLNIQTAQHQHVTENDEDVILIFGDVRSIDVKAPYSKPVLTLRQSYRDDLLIVAKTSIVNATYPFIKTQDFLKGTLSGNYLDFNHVYTEFNRLVIHNLVEGLCDAPPDDRTVSMVFSYAVLARTLYHTSNVTARLEDVALRYVRLTLARTFLQQCFDVGPRYMRFPTIDGALSVLLKLIRNSRDVDGGLKLSLTFALIFGNNTDMTKERDLENALYEMKSIHRAGLVSPLSPRQRSLLYMMAYVTHHTTAFPDIRREMLAMQTSLCSPQELYNWAPHVSSAGLTMQEMFTPCSGSGRRDYSEARIAEIVQLNPLTTKTPADLYRILAHFDRSNLTNFPALSCISHLSGYVAVTLRDVTYVVSSNVMLKGTSYPVTNLAVDKTMIVTVSPAQHPCEKTEVAHATRSIPIVKNITIGNDCEYCKSAIMEYDEVNGLSNIVYLADTADLVLVTNLDNRILASSPRTRYIMMTANGTLMEITSVIIDIRQTSIFMIMLYCSLGVLLLYGLYRLLHMI
What is the function of this protein?
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell.  Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL.  May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis.
What are the official names of this protein?
Envelope glycoprotein H, gH.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein H family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN).
Protein: ATPA_IDILO
Sequence: MQLNSNEIAELIKQRIEKFEVTSEARNEGTIMSVQDGIIRIHGLADCLQGEMVELPGNRYAIALNLERDSVGAVVMGPYADLQEGTKVKSTGRILEVPVGEKLLGRVVNTLGQPIDGKGPIEADGYEPVEKIAPGVIERQSVDQPVQTGYKSIDSMIPVGRGQRELIIGDRQTGKTALAVDAIINQKDSGIKCVYVAIGQKNSTISAVVRKLEEHGAMENTIVVAASASESAALQYLAAYSGCTMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNADYVEKFTDGKVKGQTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLFNSGIRPAVNAGVSVSRVGGSAQTKIIKKLGGGIRLALAQYRELAAFAQFASDLDESTRSQLEHGQRVTELMKQKQYKPMSVAQMAVSIYAVEKGFLKDVEIDKIMDFEESLQSFMASEYAELMAEIDKTGNYNDDIDAQLKAALEKFKQTQSW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CYB5A_ARATH
Sequence: MPTLTKLYSMEEAATHNKQDDCWVVIDGKVYDVSSYMDEHPGGDDVLLAVAGKDATDDFEDAGHSKDARELMEKYFIGELDESSLPEIPELKIYKKDQPQDSVQKLFDLTKQYWVVPVSIITISVAVSVLFSRKT
What are the official names of this protein?
Cytochrome b5 isoform A, AtCb5-A, Cytochrome b5 isoform D, AtCb5-D.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein. Note=Localizes preferentially on the chloroplast envelope. Localizes in stromule (stroma-filled tubular extensions of the plastid envelope membrane).
Protein: BRK1_BOMOR
Sequence: MRLWFCLSFFIILCLEHFPGTLADERNVPESEEKTEQFLRDLSEISRLQRRPPGFSPFRGKFHSQSLRDLSEISRLQRRPPGFSPFRGKFHSQSMRDLSEISRLQRRPPGFSPFRGKFHSQSMRDLSEISRLQRRPPGFSPFRGKFHSQSLRGLSEIKRLKTTHKIH
What is the function of this protein?
Vasodilator.  Bradykinin produces in vitro relaxation of rat arterial smooth muscle and constriction of intestinal smooth muscle.  May target bradykinin receptors (BDKRB).
What are the official names of this protein?
Kininogen-1, BOK-1.
What is the protein family that this protein belongs to?
Belongs to the bradykinin-related peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: METC_STAHJ
Sequence: MSLSKETEVIFDEHRGVDYDSANPPLYDSSTFHQKVLGGNAKFDYARSGNPNRQLLEEKLAKLEGGQYAFAYASGIAAISAVLLTLKANDHVILPDDVYGGTFRLTEQILNRFDIQFTTVNATQPKEIERAIQPNTKLIYVETPSNPCFKITDIRAVAAIAKRHHLLLAVDNTFMTPLGQSPLALGADIVVHSATKFLGGHSDIIAGAAITNRKDVADALYLLQNGTGTALSAHDSWTLAKHLKTLPVRFKQSTSNAEKLVAFLKEREEIAEVYYPGNSSLHLSQANSGGAVIGFRLKDETKTQDFVDALTLPLVSVSLGGVETILSHPATMSHAAVPEDVRNERGITFGLFRLSVGLEQPQELIADLNYALKEAFNESIIESITEQRFSS
What is the function of this protein?
Catalyzes the transformation of cystathionine into homocysteine (PubMed:19035565).  Can also catalyze, at low levels, the conversion of cystathionine into methionine and the conversion of methionine into methanethiol (PubMed:19035565).
What are the official names of this protein?
Cystathionine beta-lyase MetC, CBL, Beta-cystathionase, Cysteine lyase, Cysteine-S-conjugate beta-lyase.
What is the protein family that this protein belongs to?
Belongs to the trans-sulfuration enzymes family.
Protein: RL4_PROM9
Sequence: MTTIETLKWDGKKSGEVKLDLTVAKETSSADLIHRAVLRQLANKRQGTASTLTRSEVRGGGRKPYKQKGTGRARQGSIRTPLRPGGGIIFGPKPRSYNLDMNRKERRLALRTALMSRISDVKAVEDFGSTLKQPKTSDIINGLTRLGIQKTEKVLVILDSPSEVIKKSINNIEKVKLIAADQLNVFDILNANKLVIGQSAINKIKEVYAS
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: UPP_METM7
Sequence: MIKDERWEGVYSFEDSPYLMETLTDLRKISTENISFRKGLVRLGRYMGYELTKTMEFEKMPIQTPLEKTEGIFSKDRKNVVIITILRAAFPLMEGLIKNFESAKVGIVSASRGHAPDFKIEMNYIKVPQLNSEDTVIISDPMIATGSTLIRVLNEFKDSKPKRMLIVGVLAAPEGINAVKAEFPDVEIFVTKIDEKLNKDGYIVPGLGDAGDRAFGEPYKVSMLPQMHNLE
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: TREA_PSEAE
Sequence: MPDRTALPRAMLAAWVLLLLAACSQGPAPTPPASWGWQDASGERAIAPDEAYPELFQAVQENRLFSDQKHFVDALPLREPARIRADYLRERERPGFDLRAFVGRNFEESGSVETAPPEAGADLASHISDLWPALTRHYEQVPAHSSLLPLPKPYVVPGGRFREVYYWDSYFTMLGLAESGQHQRVRDMLDNFAYLIDTYGHIPNGNRSYYLSRSQPPFFAYMVDLQARREGDAAYRRYLPQLQKEYAYWMEGSAGLRPNEARLHVVKLADGSLLNRYWDNRDTPRQESFLEDRATAARAPQRPAGEVYRDLRAGAESGWDFSSRWLDDGRELASIRTTAIVPVDLNALLYHLERIIAKACASSALKACEQGYGARAEKRRQAIEDHLWHPAGYYADYDWQRRRPIERINAASLFPLFTGLASAERAGRTADSVAAQLLRPGGLATTTRASGQQWDEPNGWAPLQWVAVQGLRAYGRDALAEDIGRRFLAQVQQVYDREGKLVEKYDISGNQGGGGGGEYPLQDGFGWSNGVTLQLLRLYGPGAGR
What is the function of this protein?
Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system.
What are the official names of this protein?
Periplasmic trehalase, Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 37 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: SCML1_PONPY
Sequence: MMSNSSSEIDVVKTRIPTYDEDDDTILYAYETKPEFVNKEPNIVSDASCNTEEQLKTVNDVLIHCQVIYDAMQNLDKKIDVIRRKVSKIQRFHARSLWTNRKRYGYKKYSYRLAKKLKLQKMKKNEVYESFSYPESYSPTLPVSRRENNSPSNLPRPSFCMEEYQPAEPEEDPILSRTPSPVHPSDFSEHNYQPYYASDGAMYGSSSGPCLGNPRADSIHNTYSTDHASAAPPSVTRSPFENDCYIKEGSITKHPSTWSVEAVVLFLKQTDPVALCPLVDLFRSHEIDGKALLLLTSDVLLKHLGVKLGTAVKLCYYIDRLKQGKCFEN
What is the function of this protein?
Putative Polycomb group (PcG) protein.  PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development.  May be involved in spermatogenesis during sexual maturation (By similarity).
What are the official names of this protein?
Sex comb on midleg-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the SCM family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RBM4_RABIT
Sequence: MVKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYKLHGVNINVEASKNKSKASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKDYAFVHMERAEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQSGCYRCGKEGHWSKECPVDRTGRVADFTEQYNEQYGAVRTPYTMGYGESMYYNDAYGALDYYKRYRVRSYEAVAAAAAASAYNYAEQTMSHLPQVQSTGVTSHLNSTSVDPYDRHLLQNSGAAATSAAMAAAAATSSSYYGRDRSPLRRAAAVLPTVGEGYGYGPESELSQASAAARNSLYDMARYEREQYVDRARYSAF
What is the function of this protein?
RNA-binding factor involved in multiple aspects of cellular processes like alternative splicing of pre-mRNA and translation regulation.  Modulates alternative 5'-splice site and exon selection.  Acts as a muscle cell differentiation-promoting factor.  Activates exon skipping of the PTB pre-mRNA during muscle cell differentiation.  Antagonizes the activity of the splicing factor PTBP1 to modulate muscle cell-specific exon selection of alpha tropomyosin.  Binds to intronic pyrimidine-rich sequence of the TPM1 and MAPT pre-mRNAs.  Required for the translational activation of PER1 mRNA in response to circadian clock.  Binds directly to the 3'-UTR of the PER1 mRNA.  Exerts a suppressive activity on Cap-dependent translation via binding to CU-rich responsive elements within the 3'UTR of mRNAs, a process increased under stress conditions or during myocytes differentiation.  Recruits EIF4A1 to stimulate IRES-dependent translation initiation in respons to cellular stress.  Associates to internal ribosome entry segment (IRES) in target mRNA species under stress conditions.  Plays a role for miRNA-guided RNA cleavage and translation suppression by promoting association of AGO2-containing miRNPs with their cognate target mRNAs.  Associates with miRNAs during muscle cell differentiation.  Binds preferentially to 5'-CGCGCG[GCA]-3' motif in vitro (By similarity).
What are the official names of this protein?
RNA-binding protein 4, Lark homolog, RNA-binding motif protein 4.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Nucleus speckle. Cytoplasm. Cytoplasmic granule. Note=Undergoes continuous nucleocytoplasmic shuttling. Upon nuclear import colocalizes with SR proteins in nuclear speckles. Arsenite stress-induced phosphorylation increases its subcellular relocalization from the nucleus to the cytoplasm and to cytoplasmic stress granules (SG) via a p38 MAPK signaling pathway. Primarily localized in nucleus and nucleoli under cell growth conditions and accumulated in the cytoplasm and cytoplasm perinuclear granules upon muscle cell differentiation (By similarity).
Protein: SV2C_RAT
Sequence: MEDSYKDRTSLMKGAKDIAKEVKKQTVKKVNQAVDRAQDEYTQRSYSRFQDEDDDDDYYPPGETYSGEANDDEGSSEATEGHDEEDEIYEGEYQGIPSTNQGKDSIVSVGQPKGDEYKDRRELESERRADEEELAQQYELIIQECGHGRFQWALFFVLGMALMADGVEVFVVGFVLPSAETDLCIPNSGSGWLGSIVYLGMMVGAFFWGGLADKVGRKQSLLICMSVNGFFAFLSSFVQGYGFFLLCRLLSGFGIGGAIPTVFSYFAEVLAREKRGEHLSWLCMFWMIGGIYASAMAWAIIPHYGWSFSMGSAYQFHSWRVFVIVCALPCVSSVVALTFMPESPRFLLEVGKHDEAWMILKLIHDTNMRARGQPEKVFTVNKIKTPKQIDELIEIESDTGTWYRRCFVRIRTELYGIWLTFMRCFNYPVRENTIKLTIVWFTLSFGYYGLSVWFPDVIKHLQSDEYALLTRNVQKDKYANFSINFTMENQVHTGMEYDNGRFLGVKFKSVTFKDSVFKSCTFDDVTSVNTYFKNCTFIDTLFENTDFEPYKFIDSEFQNCSFLHNKTGCQITFDDDYSAYWIYFVNFLGTLAVLPGNIVSALLMDRIGRLTMLGGSMVLSGISCFFLWFGTSESMMIGMLCLYNGLTISAWNSLDVVTVELYPTDRRATGFGFLNALCKAAAVLGNLIFGSLVSITKAIPILLASTVLVCGGLVGLRLPDTRTQVLM
What is the function of this protein?
(Microbial infection) Receptor for C. botulinum neurotoxin type F (BoNT/F); binding requires glycosylation of Asn-573 (PubMed:19476346, PubMed:19650874).
What are the official names of this protein?
Synaptic vesicle glycoprotein 2C, Synaptic vesicle protein 2C.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Note=Enriched in small synaptic vesicles and adrenal microsomes, not present in chromaffin granules. Associated with both insulin granules and synaptic-like microvesicles in insulin-secreting cells of the pancreas.
Protein: GLMU_ALIB4
Sequence: MGKKSIIILAAGAGTRMKSDTPKVLHKISGKPMLYYSIKEALKLSDDITVVLYHQFEKVKAEIEKYFSNINFVIQDHKNYPGTGGAVMGITPKYEKVLVLNGDMPLIQANELEKFEINATIVMSVLELESADGYGRVIIENGNVKKIVEQKDASEDELKITTANAGIYQFETKFLLENLPKLDNNNAQKEYYITDLVEMAISQGKVLKPLVVNEENFKGVNSKVELADAEVIHQNRIKKEFMKAGVIMRLPDTIYIEEGVEIEGESIIENGVSLLGNAKIINSHIKTNSVVEDSIVKDSDVGPMGRVRPGSELTNTHIGNFVETKKAKLTGVKAGHLSYLGDCSIDEGTNIGCGTITCNYDGVNKHQTIIGKNVFVGSDTQFVAPVNIEDDVLIGAGSTVTGNVKKGELYLTRAKAKTIDGFFYKHFSSKKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MENG_PHOV8
Sequence: MNYPQEKIKPYNADEKKSVQVEKMFDNIAPAYDQLNHALSWNIDKSWRRKAINWLEPFHPQHIMDVATGTGDFAIQACQTLHPQELIGTDISEGMMNVGREKVKAAGLDSRISFAKEDCTALTFPDKRFDAITVAFGVRNFEDLDKGLREMHRVLKDNGKLVILELSEPDWFPMKQLYAVYSKIVIPTLGKLLSKDRSAYTYLPQSIKAFPQGEIMTDIIRKAGFNQVSFKRLTLGICTLYLATK
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
What are the official names of this protein?
Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: FB164_ARATH
Sequence: MCMTMMSDISQDLLEEILSRVPITSLRAVKSTCKRWKDLLNDPSFSKKYGGKRDNEFLAIMTSGSRASLMSVNLHGPRDNKDLEDPFIKQIGELNQDQIFKVFHCDGLLLCITNEDNTRLVVWNPYLAQTRCIQPIDKFYIYDWYCLGYDKDKNHKILVVYSPMFGRIEYEIYSFLSKSWIVLSFPTDWQISRDECLSLKGNTYFIAYKKMEVEEVGFQEFLLCFDFTNERFGPLLPLPFQCYNQTSLVLSTVQEEQLAVLCKRCDAYETKIWITTKIEPNAVSWSYFLKFDFKVDISGGSFFVDVEEKVAVLFCINREKEKGINNKTYMIGEDGYYKEVDLGESNWCPSMCSYVPSCVQV
What are the official names of this protein?
Putative F-box protein At3g19560.
Protein: ETF1_MYXVL
Sequence: MNSAVIELFRHHVNNIPNILPHQLATLDYLVRSIIDENKSVLLFHIMGSGKTIIALLFALVASRFKKVYILVPNINILKIFNYSMDVVINLFNADYILENIFIYSTTSFYSINYNDNVINYNGLSRYNNAIFIIDEAHNIFGNNTGELMTVIKNKNKIPFLLLSGSPITNTPITLSNIISLMSDEEINFGDIIIQGKKVFQILLNEHGVNVLKNILKGRISYYKMPDTDLPGIQYHGKSFLDTRVVYCNMSKLQEKDYINVRKMCNNEMFEKNMNNVSLAVLGQLNLINNLDILFQEQDKELYPNLKINNGVLYGEELVTLNISSKFKYFITKIESLKGKHFIYFSNSTYGGLIIKYIMLSNGYSEYNGSQGTHPKLIHGRPKTFAIVTSKMKASLEDLLVTYNSLANDDGSQIMFLFSSNIMSESYTLKEVRNIWFMTIPDTFSQYNQILGRSIRKFSYKDITQPVNVYLLAAVYSDFNDTIESLDDYSLEEINTLPFDIKKLLYLKFKTKETNRIYSILENISDSYTQPPHPHIVEIVLGEIVRQFFYHHSRIKHNDERLLAAVKSVLTNTEAAKKYIKEIVDGHFFVSNKVFDKSLLYMYNDEIITVPFKLSHEPFVWGVNFRKEYNVVSSP
What is the function of this protein?
Acts with RNA polymerase to initiate transcription from early gene promoters.  Is recruited by the RPO-associated protein of 94 kDa (RAP94) to form the early transcription complex, which also contains the core RNA polymerase.  ETF heterodimer binds to early gene promoters (By similarity).
What are the official names of this protein?
Early transcription factor 70 kDa subunit, ATP-dependent helicase VETFS, ETF small subunit.
What is the protein family that this protein belongs to?
Belongs to the helicase family. VETF subfamily.
What are the subcellular locations of this protein?
Virion. Note=All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome. This is necessary because viral early mRNAs are synthesized within minutes after virus entry into the cell and are extruded through pores in the core particle.