PharMolix/UniProtQA huggingface dataset:
Protein: AMPA_BUCA5
Sequence: MNFFIKSCFLDKEKTDCIVVSVFELSELSDSAIYLDKCSNGHITSLIKLGDIQGKIGDTLMLYKVPKILSKRILLVGCGKKDEINIIRFKKILKNTIHAIKKKSIKNIVYSFSNINIDNIYWMIRRMVLSLKESLYETIKINNTNIKNTNIHSITLNIIKKNDLFIAKTALKHALAIDHAITSTKNLSNLPPNICNPLYLSYKAQELSKKYENNIVVEIIDIKKMKELGMNAYIAVGNGSKNKPFMSVIKYSGNNIVNKKIIAFVGKGLTFDSGGISIKPALHMHEMKYDMCGAAAVYGTLIMAAELQLPLTVIGILSGCENMVGSHSFRPGDVLTTMSGQTVEILNTDAEGRLVLCDSLTYLERFSPDIVIDVATLTGACVTALGESVSGLFSNNEELSNQLLHASQETDDKIWSLPLFSEYHKELNSDIADFSNIGRGKAGAITAACFLSKFTKKYNWAHLDIAGTAWKSGKKSGATGRPVELLCQFLLNQSNYIYN
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_METM6
Sequence: MNITIISVGKIKEKYLSGAIIEYSKRISRYSKLDIIEVADEKTPENPSDVEKSKLLEKEAERILKYLKKDSFVITLEILGKELTSESLAKKINDLSISGKSDITFIIGGSLGLSRNISEISDFKLSFSKMTFPHQLMRVILLEQIYRSFRIINGEPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Putative ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS7_BACAN
Sequence: MRESSQIRETTETKIKLSLQLDEGKNVSVQTGVGFFDHMLTLFARHGRFGLQVEAEGDVFVDAHHTVEDVGIVLGNCLKEALQNKEGINRYGSAYVPMDESLGFVAIDISGRSYIVFQGELTNPKLGDFDTELTEEFFRAVAHAANITLHARILYGSNTHHKIEALFKAFGRALREAVERNAHITGVNSTKGML
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSX_PSEAB
Sequence: MSAPIIAIDAMGGDFGPHCVVPASIAFLAENSSSQLILVGQPALLEELLSRYPSLDRQRLRVHAASEVIGSDERPSQALRGKPDASMRVALELVRDGRAHACVSAGNTGALMALSRHLLKTLPGIDRPAMVTAVPTEKGHCHLLDLGANVDCSAEHLYQFAVMGAVAAEALGCVSPRVALLNVGTEEIKGNQQVKLAASLLQKAQGLNFSGYIEGDGLYRGEADVVVCDGFVGNILLKASEGLAAMVSARIEQRFRDGLAAKLVGALALPLLRRLRGDIAPARYNGASFLGLQGIVVKSHGSAAEEGFQSALRRAALEVRENLPQRLHGRLEHLLL
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: LEUD_BURM9
Sequence: MEKFNVHTGVVAPLDRENVDTDAIIPKQFLKSIKRTGFGPNAFDEWRYLDHGEPGQDNSKRPLNPDFVLNQPRYQGASVLLARKNFGCGSSREHAPWALQQYGFRAIVAPSFADIFFNNCYKNGLLPIVLTEQQVDHLFNDTYAFNGYQLTIDLDAQVVRAPDGREYPFEITAFRKYCLLNGFDDIGLTLRHADKIRQFEAERLAKQPWLDNRLVG
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: VATB_THEKO
Sequence: MIMPGMEYSTVSKIYGPLMIVQGVKGVAYGEVVEIETESGEKRKGQVLEAREDMAIVQVFEGTRDLDIKTTRVRFTGETLKVPVSMDMLGRIFNGIGKPIDGGPEIIPEDRRDVHGAPLNPVARAYPRDFIQTGISAIDGMNTLVRGQKLPIFSGSGLPHNMLAAQIARQAKVLGEEEQFAVVFAAMGITYEEANFFKKSFEETGAIERAVLFLNLADDPAIERIITPRMALTVAEYLAFDYDMQVLVILTDMTNYAEALREISAAREEVPGRRGYPGYMYTDLATIYERAGRVRGKKGSITQMPILTMPDDDITHPIPDLTGYITEGQIVLSRELHRKGIYPPIDVLPSLSRLMKDGIGKGRTREDHPQLSQQLYAAYAEGRSLRDLVAVVGEEALSETDRKYLKFADRFEREFVAQRYDEDRSIFETLDLGWELLAELPESELKRVRKEYILKYHPKYRKRGE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The archaeal beta chain is a regulatory subunit.
What are the official names of this protein?
V-type ATP synthase beta chain, V-ATPase subunit B.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: DNLJ_MESH7
Sequence: MKKNSQIRAKIIELREKIEKWNHHYYQLQNPLVDDLVYDKTLRELEKLERENFFLFSLEELNQSPSQKVGSKITSKFEKVAHSSPMLSLNKAYSNEELEKWAKKAREILKTVTFFVEPKIDGIALSLFYQNGNLIKALTRGDGVFGENVLVNALKINDEFIPKKINYLEDLEVRGEIYIDNSTFASLQLETKKFKNPRNAASGILRRYKNHKPKIDAKSIKFLEEESDFRYLKSFFYTLVNPEKHKINSQFDSINFLRNLGFQVNPFQKKCSDLKDVFNFISIIKQKRDFLNYNIDGVVVKVNEFSIYEKLGSTSKFPHSAIAFKFEDDIAKTKLLAIFATIGRTGKVTYNAKIEPVTLAGSKISSAILPNYSYIENLKLNLNTEVYIKKAGEIIPQIIGSVHNYPKTNFSIVKNCPKCNSELVNSESGLDQFCQNQFCPEIILQKIVHFCSKNALNIESLAQKRIEKFLEKGLISSACDIFYLKDKLELIYERLSNKNQLLTKQNASQSMQIKSIMKLLNEVERAKNIDFYRLIFGLGIRNVGLKAAKILSRYASNLSELRNLDFNLLKNQHDFGPVIIESLIDYFNNQKNSEQLNCLETVGFNFKTTFLTNQSNSWASFAISGKLSKPRDEYVRIIEESGASFHESVTKKTDFLLLGQSAGSKIEKAKKAGIKIINEVQFFDLIKNSKKT
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: RNPA_CHLAB
Sequence: MYRSTLPKRARVLKRRQFLYISRAGSRCQGSQVIFHVAPSKYPGCCKLGITVSKKFGKANKRNYFKRIVREAFRLKRHSLPSCQIVVMPKNKHRPKFEELLQDFTQQIPEALNSKFSKNKSTIGGEYSPKNEQCESELP
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: Y692_PELUB
Sequence: MPSFDVISKVSYPEFDNALANCLREIGNRFDFKGLHISIERKDKIITTLAPDELKLKQVNELLQVHLIRRKVDPRVLSIKNSENAAGSSIRQVSELQEGISQENAKKIITEIKKLKLKIQIKIQGEELRAEGKKRDDLQEAMSAITAIDIGLPVEFVNFRD
What are the official names of this protein?
UPF0234 protein SAR11_0692.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: AAEA_ECOK1
Sequence: MKTLIRKFSRTAITVVLVILAFIAIFNAWVYYTESPWTRDARFSADVVAIAPDVSGLITQVNVHDNQLVKKGQVLFTIDQPRYQKALEEAQADVAYYQVLAQEKRQEAGRRNRLGVQAMSREEIDQANNVLQTVLHQLAKAQATRDLAKLDLERTVIRAPADGWVTNLNVYTGEFITRGSTAVALVKQNSFYVLAYMEETKLEGVRPGYRAEITPLGSNKVLKGTVDSVAAGVTNASSTRDDKGMATIDSNLEWVRLAQRVPVRIRLDNQQENIWPAGTTATVVVTGKQDRDESQDSFFRKMAHRLREFG
What is the function of this protein?
Forms an efflux pump with AaeB.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeA, pHBA efflux pump protein A.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: GPX4_CITSI
Sequence: MASQSKTSVHDFTVKDAKGQDVDLSIYKGKLLLIVNVASQCGLTNSNYTELSQLYDKYKNQGLEILAFPCNQFGAQEPGDNEQIQEFACTRFKAEFPIFDKVDVNGDNAAPLYKHLKSSKGGLFGDSIKWNFSKFLVDKEGNVVERYAPTTSPLSIEKDIKKLLETA
What is the function of this protein?
Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione.
What are the official names of this protein?
Probable phospholipid hydroperoxide glutathione peroxidase, PHGPx, Salt-associated protein.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX7S_HUMAN
Sequence: MLWNLLALHQIGQRTISTASHRHFKNKVPEKQKLFQEDDGIPLYLKGGIADALLHRATMILTVGGTAYAIYQLAVASFPNKGVTSIIPAITWFTFIQLSMDQKSDK
What are the official names of this protein?
Putative cytochrome c oxidase subunit 7A3, mitochondrial, Cytochrome c oxidase subunit VIIa 3.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase VIIa family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane.
Protein: SCMH1_MOUSE
Sequence: MLVCYSVLACESLWDLPCSIMGSPLGHFTWDKYLKETCSVPAPVHCFKQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSSEIQPIGNCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIKIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGAEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQPPGTKVVIPKNPSPSSDVSTEKPSIHSTKTVLEHQPGQRGRKPGKKRGRTPKILIPHPTSTPSKSAEPLKFPKKRGPKPGSKRKPRTLLSPPPTSPTTSTPEPDTSTVPQDAATVPSSAMQAPTVCIYLNKSGSTGPHLDKKKIQQLPDHFGPARASVVLQQAVQACIDCAYHQKTVFSFLKQGHGGEVISAVFDREQHTLNLPAVNSITYVLRFLEKLCHNLRSDNLFGNQPFTQTHLSLTATEYNHNHDRYLPGETFVLGNSLARSLETHSDLMDSALKPANLVSTSQNLRTPGYRPLLPSCGLPLSTVSAVRRLCSKGVLKGKKERRDVESFWKLNHSPGSDRHLESRDPPRLSGRDPSSWTVEDVMQFVREADPQLGSHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKLSFHIDRLKQVFWKRETILWSREGLSREVWPISEDTALGHFFSGMDKVFGSLSKR
What is the function of this protein?
Associates with Polycomb group (PcG) multiprotein complexes; the complex class is required to maintain the transcriptionally repressive state of some genes.
What are the official names of this protein?
Polycomb protein SCMH1, Sex comb on midleg homolog 1.
What is the protein family that this protein belongs to?
Belongs to the SCM family.
What are the subcellular locations of this protein?
Nucleus.
Protein: VDH_PSEUH
Sequence: MFHVPLLIGGKPCSASDERTFERRSPLTGEVVSRVAAASLEDADAAVAAAQAAFPEWAALAPSERRARLLRAADLLEDRSSEFTAAASETGAAGNWYGFNVYLAAGMLREAAAMTTQIQGDVIPSNVPGSFAMAVRQPCGVVLGIAPWNAPVILGVRAVAMPLACGNTVVLKSSELSPFTHRLIGQVLHDAGLGDGVVNVISNAPQDAPAVVERLIANPAVRRVNFTGSTHVGRIIGELSARHLKPAVLELGGKAPFLVLDDADLDAAVEAAAFGAYFNQGQICMSTERLIVTAVADAFVEKLARKVATLRAGDPNDPQSVLGSLIDANAGQRIQVLVDDALAKGARQVVGGGLDGSIMQPMLLDQVTEEMRLYREESFGPVAVVLRGDGDEELLRLANDSEFGLSAAIFSRDVSRAMELAQRVDSGICHINGPTVHDEAQMPFGGVKSSGYGSFGSRASIEHFTQLRWLTIQNGPRHYPI
What is the function of this protein?
Catalyzes the NAD-dependent oxidation of vanillin to vanillic acid.
What are the official names of this protein?
Vanillin dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: CC103_XENTR
Sequence: MDDLETLDFRELERELANALAADQKYSRENDAKFRAIHQKVASYEEFRDIVLASNLKPLERKDKVGGESKQPWNPSFNTTNCTQKSEDVMLKKSLSDPTNAFEFARDWRRLGNVEKYDFLLQLGAEKLSQLFHAEVCSGLLGEFLLVLSESFQAIHVEKVLKILQTLAETKRFDLNLIFISRSEVESSQKLFGKLQTCVGAMKDEKRGLGDENLRKLMACYKISC
What is the function of this protein?
Dynein-attachment factor required for cilia motility.
What are the official names of this protein?
Coiled-coil domain-containing protein 103.
What is the protein family that this protein belongs to?
Belongs to the CCDC103/PR46b family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, cilium, flagellum.
Protein: NPD_THEKO
Sequence: MLGHAAKLLARARFAIAFTGAGISAESGIPTFRGRNGLWKTYRAEELATPEAFKRDPHLVWEFYKWRMRKILKAEPNPAHKALAELENMGVLKAVITQNVDDLHREAGSRKVVELHGNIFRVRCVSCSYRENLKESGRVFEFVREKELPKCPKCGSLLRPDVVWFGEPLPREALEEAFSLAERADVVLVVGTSGVVYPAAYVPYIVKERGGKVIEVNVERSGITPIADVFIRGKAGEVMPELLRRVKDIMAERNHYG
What is the function of this protein?
NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins.  Modulates the activities of several proteins which are inactive in their acylated form.  Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription.
What are the official names of this protein?
NAD-dependent protein deacylase, Regulatory protein SIR2 homolog.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class III subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T39AB_XENLA
Sequence: MPGGRRGPSRQQLSRSALPSLQTLVGGMCGNGTGLRNRNGSAIGLSAPPITALITPEPVRHCHIPELPVDGGLVFEFLFFIYLLVTLFTQYINIYKTVWWYPYNHPASCTSLNFHLIDYHLAAFITVMLARRLVWALISQASQVGTSSVVKYSALIIGRLVLLTLCGWIFCWTTVNLFRNHSVLNLLFLGYPFGVYVPLCCFHQDNRSQPLPTDCGYLVPDSLVHEGANGVGGLVRPKDFLSLLRESLREQFNSPPSIPSHSCPLSPDLIRNEVECLKSDFNRRIKEVLFNSLFSAYYVAFLPLCFVKSTQYYDMRWSCEHLIMVWINAFVMLSTQLLPPKYCDLLHRSASHLGKWQKLEHGSYSNAPQHVWSENTVWPQGVLVRHSRSLYKAVGSYNVAVPSEISHARFYFLFHRPLRLLNLLLVIEGSLVLYQLYSLLRAEKWNHTLSIALILFCNYYVLFKLLRDRIVLGRAYSYPLSSYGLKPH
What are the official names of this protein?
Transmembrane protein 39A-B.
What is the protein family that this protein belongs to?
Belongs to the TMEM39 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NUOD_XYLF2
Sequence: MNQIRQAPAASASNATESKQEIRNYTMNFGPQHPAAHGVLRLILEMDGETVVRADPHIGLLHRGTEKLAESKPFNQSIGYMDRLDYVSMMCNEHAYVRAIETLIGIQAPERAQYIRTMFDEITRILNHLMWLGSNALDLGAMAVMLYAFREREELMDVYEAISGARMHAAYYRPGGVYRDLPDTMPKYKESRWHKGKALKRLNAAREGSMLDFLEHFTDTFPQRIDEYETLLTDNRIWKQRTVGVGVIEPDVAKAWGMTGVMLRGSGIAWDLRKKQPYAKYDAVDFDIPLGTCGDCYDRYLCRVAEMRESNRIIKQCVQWLKMNPGQVMVENCKVAPPKRESMKDDMEALIHHFKLFSEGYCVPAGETYSAVEAPKGEFGCYLISDGANKPFRVHLRAPGFAHLSSMDAVVRGYMLADVVAMIGTYDLVFGEVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TYSY_VESOH
Sequence: MKQYLDFLKLVKNIGVYKTDRTNTGTTSMFGYQMRFDLSKGFPLVTTKHVHLPSVVYELLWFLNGDTNIKYLQDNGVRIWNEWADENGDLGPVYGTQWRHWKNIKDKSIDQISKVVEQIKNTPNSRRIIVSAWNVGELENMALPPCHVFFQFYVADGKLSCQLYQRSADIFLGVPFNIASYSLLTHMMAQQCDLEVGDFIWSGGDCHIYSNHYKQVEIQLSRTPKALATLKIKRKPENIFDYSFEDFEFVNYIFDAPIKAPVAI
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIF3L_DROWI
Sequence: MYGGDEFSNNGDFYDDYAHTGDPQLDLEYERSYYTSRMPDNVKYFLMNFCQAIKDGNLYDIQNMYENTFPQISDHHFDKTAWPEEQEVASIVDNEKVFLILYKELYFRHIHARIPGGPKLDQRINSFFNYCDFFNLIISAQNPVMLELPDIWLWELVDEFVYQFQNFAQYRARLTDKSQDEIQQLCVNHSNVWSILCILNVLHSLVDISNIKKQLEVISQGVDPQTVAGDFGKLSFYKMLGYFSLVGLLRVHSLLGDYYQAIKVLEPIEIHKKSAYSHIPACQISTSYYVGFAYMMMRRYADAIRTFSDILLYVQRTKQLYSTRSYQNDQINKQAEQMYHLLAICLVLHPQCIDESIQQVLREKNYHDAMFKMQCGDLDVFKSFFIFACPRFVSPCPPAADAPMEDYVKDPMEHQLLVFMDEVRQQKDLPTTRSYLKLYTTLPLAKLASFIDPNASEDDVSKLLIRLLCFKHKMRNLVWSKGPSGLEGSFKSGSELDFYIDDDMIHIADTKVSHRYGDFFVRKILKFNDLNRKLKGVNI
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit L, eIF3l.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit L family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y508_HAES1
Sequence: MAGHSKWANIKHRKAAQDAQRGKIFTKLIRELVTAAKLGGGDVGANPRLRAAVDKALSNNMTRDTINRAIERGVGGGDGTNMETRIYEGYGPGGTAVMVECLSDNANRTISQVRPSFTKCGGNLGTEGSVGYLFSKKGLILVESADEDALTEAAIEAGADDIQVQEDGSVEIYTAWEDLGLVKDGIEVVGFKVVNAEVTMIPSTMVDLDAETAPKLLRLIDMLEDCDDVQNVYHNGEISDEVAALL
What are the official names of this protein?
Probable transcriptional regulatory protein HS_0508.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCDBB_PANTR
Sequence: MENGGTRTQQIRQVLLLFVLLGMSQAGSETWSFSVAEEMQSGSFVGNLAKDLGLKVRELSSRGARVVSNDKKQRLQLDINTGDVLLSETLDREELCGSIEPCVLHFQVLMQNPTQFLQIELQVRDINDHSPIFLEKQMLLEIPENSPVGAVFLLESAKDLDVGINAVKSYTISPNSHFHIKMRVNPDNRKYPELVLDKALDYEELPELSFILTALDGGSPPRSGTALVRVVVVDINDNSPEFEQAFYEVKIPENSILGSLILTVSAWDLDSGTNGEICYTLSHASEDIRKTFEINQKSGDITLTAPLDFETIESYSIIIQATDRGGLFGKSTVRIQVIDVNDNAPEITVSSITSPIPENTPETVVMVFSIQDIDSGDNGRIVCSIPEDLPFVLKSSVENYYTLETERPLDRESTAEYNITITVTDLGIPRLKTEHNTTVLVSDVNDNAPTFTQTSYTLFVSENNSPALHIGSVSATDRDSGTNAQVNYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAFEFRVGATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFXVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSATATLHVLLVDGFSQPFLPLPEAAPAQAQTDFLTVYLVVALASVSSLFFFSVLLFVAVRLCRRSRAASVGSCSVPKGPFPGHLVDVSGTGTLSQSYQYEVCLTGGSETNEFKFLKPVIPNIQAKGLGKNSEENSTFQNSFGFNF
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.  May be involved in the establishment and maintenance of specific neuronal connections in the brain.
What are the official names of this protein?
Protocadherin beta-11, PCDH-beta-11.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: PENC1_PENCI
Sequence: MGFLKVLATSLATLAVVDAGTLLTASNTDAVIPSSYIVVMNDDVSTAEFNTHREWATNVHARLSRRKNGETGPGKHFEINGLKGYTASFDESTAKDIANDPAVKYIEPDMIVNATANVVQSNVPSWGLARISSKRTGTTSYTYDSTAGEGVVFYGVDTGIDISHSDFGGRAKWGTNVVDNDNTDGNGHGTHTASTAAGSKYGVAKKATLVAVKVLGADGSGTNSGVISGMDWAVKDAKSRGANGKYVMNMSLGGEFSKAVNDAAANVVKSGIFLSVAAGNEAENASNSSPASAAEVCTIAASTSTDGSASFTNFGSVVDLYAPGQSITAAYPGGGSKTLSGTSMAAPHVAGVAAYLMALEGVSAGNACARIVQLATSSISRAPSGTTSKLLYNGINV
What is the function of this protein?
Serine protease (PubMed:10103041, PubMed:7763554).  Hydrolyzes azocasein (PubMed:10103041).  Cleaves peptide bonds of the oxidized insulin B chain preferably at 15-Leu-|-Tyr-16, but also at 4-Gln-|-His-5 and 24-Phe-|-Phe-25, and to a lesser extent at 5-His-|-Leu-6 and 25-Phe-|-Tyr-26.  Hydrolyzes amide bonds between amino acids and 7-amino-4-methylcoumarin (AMC) in vitro (PubMed:7763554).
What are the official names of this protein?
Subtilisin-like serine protease Pen c 1, Alkaline serine protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: EFP_TREPS
Sequence: MIRGGDIAKGTVLLHKGAPYLVVEREFVNPGKGAAFARVKMKHLRDGSVLTQTVKTSDTVEDAVVDSHRAQYQYDDGECFVFMDTRSFEQIFVSKGNVPGRERYLREGDEYDILIWNGESIDIKIPTKMVFRVAHSEPYLKGDTVSGATKPVTTETGLVVRVPLFIKQGEKILINTETNEYQERVND
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECY_STAAR
Sequence: MIQTLVNFFRTKEVRNKIFFTLAMLVIFKIGTYIPAPGVNPAAFDNPQGSQGATELLNTFGGGALKRFSIFAMGIVPYITASIVMQLLQMDIVPKFSEWAKQGEVGRRKLNNVTRYLAISLAFIQSIGMAFQFNNYLKGALIINQSIMSYLLIALVLTAGTAFLIWLGDQITQFGVGNGISIIIFAGILSTLPASLIQFGQTAFVGQEDTSLAWLKVLGLLVSLILLTVGAIYVLEAVRKIPIQYAKKQTAQRLGSQATYLPLKVNSAGVIPVIFAMAFFLLPRTLTLFYPDKEWAQNIANAANPSSNVGMVVYIVLIILFTYFYAFVQVNPEKMADNLKKQGSYVPGIRPGEQTKKYITKVLYRLTFVGSIFLAVISILPILATKFMGLPQSIQIGGTSLLIVIGVAIETMKSLEAQVSQKEYKGFGGR
What is the function of this protein?
The central subunit of the protein translocation channel SecYEG.  Consists of two halves formed by TMs 1-5 and 6-10.  These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back.  The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug.  The plug probably moves laterally to allow the channel to open.  The ring and the pore may move independently.
What are the official names of this protein?
Protein translocase subunit SecY.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NSP6_ROTH7
Sequence: MNHLQQRQLFLENLLVGVNNTFHQMQKHSINTCCQSLQKILDHLILLQTIHSPAFRLDRMQLRQMQTLACLWIHQHNHDHQAMLGAIKWISPLIKELR
What are the official names of this protein?
Non-structural protein 6, NSP6.
What is the protein family that this protein belongs to?
Belongs to the rotavirus A NSP6 family.
What are the subcellular locations of this protein?
Host cytoplasm. Host mitochondrion. Note=Found in spherical cytoplasmic structures, called viral factories, that appear early after infection and are the site of viral replication and packaging.
Protein: O26G_CONVC
Sequence: MQKLIILLLVAAVLMSTQALFQEKRPKEKIDLLSKRKTDAEKQQKRYCSDDSQPCSHFYDCCKWSCNNGYCP
What is the function of this protein?
Inhibits voltage-gated ion channels.
What are the official names of this protein?
Conotoxin Vc6.16.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O2 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CLPX_HERA2
Sequence: MAQSAFMPPTYYCSFCGRNQDEVDRLVTGPGALFICNECIELLSAIIANEERKEAPHAPILPPTLPIPHAIRDHLDEYVIGQDRAKKVMAVAVYNHYKRLRAQAQGDTDVEIQKSNILLVGPTGSGKTLLAQTLARMLDVPFAIADATALTEAGYVGEDVETILLRLIQAADGDVDRAQMGILYIDEIDKIARKADNPSITRDVSGEGVQQALLKILEGGVVNVPPMPGRKHPQQEFIPFDTTNVLFICGGAFEGLEHHIAERMGSGGTLGFGKTIVKEERLERSKKLLSLVNPDDLLHFGFIPEFIGRMPVVAALTPLDKDAMMRILTEPRNAIIKQYQKMLALDHVQLEVSGDAMEAIVERALAGKTGARGLRTAVEEILLDVMFDLPSETDVVRCVITAETVRDGAMPTLIRRTSSRSRAGKQPTTKAS
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.