PharMolix/UniProtQA huggingface dataset:
Protein: KAS1_STRCO
Sequence: MTRRRVAVTGIGVVAPGGIGTPQFWRLLSEGRTATRRISLFDPSGLRSQIAAECDFEPSDHGLGLATAQRCDRYVQFALVAASEAVRDANLDMNREDPWRAGATLGTAVGGTTRLEHDYVLVSERGSRWDVDDRRSEPHLERAFTPATLSSAVAEEFGVRGPVQTVSTGCTSGLDAVGYAYHAVAEGRVDVCLAGAADSPISPITMACFDAIKATSPNNDDPAHASRPFDADRNGFVMGEGAAVLVLEDLEHARARGADVYCEVSGYATFGNAYHMTGLTKEGLEMARAIDTALDMAELDGSAIDYVNAHGSGTQQNDRHETAAVKRSLGEHAYATPMSSIKSMVGHSLGAIGSIELAACVLAMAHQVVPPTANYTTPDPECDLDYVPREARERTLRHVLSVGSGFGGFQSAVVLSGSEGGLR
What is the function of this protein?
Involved in developmentally regulated synthesis of a compound biosynthetically related to polyketide antibiotics which is essential for spore color in Streptomyces coelicolor.
What are the official names of this protein?
Putative polyketide beta-ketoacyl synthase 1, WhiE ORF III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
Protein: CYB6_CUSGR
Sequence: MSNVNKVYDWFEERLEIQAIADDITSKYVPPHVNIFYCLGGITLTCFLVQVATGFAMTFYYRPIVNEAFASVQYIMIEANFGWLIRSVHRWSASMMVLMMILHVFRVYLTGGFKKPRELTWVTGVLLGVLTASFGVTGYSLPWDQTGYWAIKIVTGVPEAIPLIGAPMVELLRGSASVGQFTLTRFYSLHTFVLPLITIVFMLMHFLMIRKQGISGPL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetB subfamily.
What are the subcellular locations of this protein?
Plastid thylakoid membrane; Multi- pass membrane protein.
Protein: SSRP_FRATH
Sequence: MSKHKVSPATIAKNKKALHDYTILEKFEAGIVLQGWEVKSIRAGKVQMVDSHVHIKHGEAWLFNCLITPLLSASTHVVADAAATRKLLLNRREINKIMGRIEQKGFTCIPLSMYWKGPRVKVEIALAQGKKVHDKRQAQKDKDWAREKDRLFKKAYK
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: RL24_PHOLL
Sequence: MAAKIRRDDEVIVLTGKDKGKRGKVKQVLSTGKVIVEGINLVKKHQKPVPALNQPGGIVEKEAAIQVSNVAIFNAATGKADRVGFRFEDGKKIRFFKSNSETIK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: UREE_FLAJ1
Sequence: MIINEIEGSLREFDITNRVVDYLEIEWFESTKRIQRKKSKNGQEVAIKFLKEGQRLKHEDVIYADDQKIIVVDIIPCDAIVVKPKSLLEMGNVCYEIGNKHLPMFIQNDEVLLPFEEPIFKWLSASGYHTEKVFTRLTNIVNSTVQPHGHSESSSLFFKIMNIAK
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRGV5_HUMAN
Sequence: MRWALLVLLAFLSPASQKSSNLEGGTKSVTRPTRSSAEITCDLTVINAFYIHWYLHQEGKAPQRLLYYDVSNSKDVLESGLSPGKYYTHTPRRWSWILILRNLIENDSGVYYCATWDR
What is the function of this protein?
V region of the variable domain of T cell receptor (TR) gamma chain that participates in the antigen recognition (PubMed:24600447).  Gamma-delta TRs recognize a variety of self and foreign non-peptide antigens frequently expressed at the epithelial boundaries between the host and external environment, including endogenous lipids presented by MH-like protein CD1D and phosphoantigens presented by butyrophilin-like molecule BTN3A1.  Upon antigen recognition induces rapid, innate-like immune responses involved in pathogen clearance and tissue repair (PubMed:23348415, PubMed:28920588).  Binding of gamma-delta TR complex to antigen triggers phosphorylation of immunoreceptor tyrosine-based activation motifs (ITAMs) in the CD3 chains by the LCK and FYN kinases, allowing the recruitment, phosphorylation, and activation of ZAP70 that facilitates phosphorylation of the scaffolding proteins LCP2 and LAT.  This lead to the formation of a supramolecular signalosome that recruits the phospholipase PLCG1, resulting in calcium mobilization and ERK activation, ultimately leading to T cell expansion and differentiation into effector cells (PubMed:25674089).  Gamma-delta TRs are produced through somatic rearrangement of a limited repertoire of variable (V), diversity (D), and joining (J) genes.  The potential diversity of gamma-delta TRs is conferred by the unique ability to rearrange (D) genes in tandem and to utilize all three reading frames.  The combinatorial diversity is considerably increased by the sequence exonuclease trimming and random nucleotide (N) region additions which occur during the V-(D)-J rearrangements (PubMed:24387714).
What are the official names of this protein?
T cell receptor gamma variable 5.
What are the subcellular locations of this protein?
Cell membrane.
Protein: DP2L_METLZ
Sequence: MAELVTSPAYRAYLDGLIAGLDRAMEIANKAKSLGVDPRPYVEIPIASDLAGRVEALLGYKGVAAKIRELEDRMSREEAALKIGDAFVGKEFGESTREDILDHAIRTSMALLTEGVVAAPTEGIGKVAVRRNDDGTEYLSIYYAGPIRSAGGTAQALSVLVGDYVRRLLNIDRYKPREEEIERYVEEIKQYNNIQSMQYLPKDDDIRLIIRNCPICIDGEPTEQEEISGYRNLERVETNVVRGGMGLVIAEGIGLKAPKIQKNVAKMNLDGWEWLEELISGNTPAQEVEEEPGVHPKDKYMRDMLAGRPSFSYPMRKGGFRFRLGRCRNTGLATCGFNPATLHILDDYLAVGTQMKVERPGKACGVVPCTDIEGPTVRLKSGELRRIDTLDDANKYYDQVEYILDIGEILISFGEFMENNHVLMPPSYCEEWWIQEGGPRHPKNEAEALSFVLEGAYLHPDYTWFWDDCSEGQLIFLSDKVAGTGSLREGVLYIPEDPAVKSVLEELLVPHTVEEGFYVVRTPLALIMGLGLTDTLAKSPTWKTLPPFSNGLSMAISLSGLKMRSKAGTRVGGRMGRPGKSAPRKMKPPVHVLFPIGESGGMKRSIDNAAKICSSDSEENFRGTSVTTGQVEGLIQVQTGERRCPKCGTVTFKSRCADCGTHTDAVYRCPHCNQLGEEGQESCPKCGANLVCSKESIVSLGQEYAAALKNVGMSASSSPELKGVRGLISRERVVEPLEKGLLRAKNNIFVFRDGTIRYDMIDLPLTHFRPAEVGVSVEKLRSIGYTQDMHGADLTDASQLVELHPQDIMVSVDCGEYLVRVAAYVDELLEKVYGMEAFYHVKTPEDLVGHLVMGLAPHTSAGVLARIVGFTKAKAGYAHPYYHAAKRRNCDGDEDCVMLLMDGLLNFSRSFLPSTRGGTMDAPLVLTTTLNPKEVDKETLNVDVMPRYPLEVYTACLTYRAPKEVGKFVDYVEKRVETPGQFEGFSFTHDTTDISEGPIDTMYTNPILKGTADKIKAELGLADRIRAVDTNDLAERIINSHLMPDMIGNLRSFSKQAFRCPKCKTSYRRIPVSGKCNKCGGPVKATMHKGNVTKYLEISKYMAEHYTLSDYTNQRIQVTEMNINSTFGEEEKVQMDLSDFF
What is the function of this protein?
Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction.  Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity).
What are the official names of this protein?
DNA polymerase II large subunit, Pol II, Exodeoxyribonuclease large subunit.
What is the protein family that this protein belongs to?
Belongs to the archaeal DNA polymerase II family.
Protein: NPIIA_ASPFU
Sequence: MKVTILASAILALINGALALPANTPTLDVTLTQVDNTRIKATVKNTGNEKVTFVHLNFFQDAAPVKKVSLFRNATEVEFTGIKRRLLTEGLSDDALTTLAPGATFEDEFDVASTADLTEGGTVTIRTDGFVPITTDRKVSGYIPYQSNELEIEVDAAKAAAVPQAIKLLDRRTKVASCSGSRASALSTALRNAASLANAAASAASSGSSTRFQEYFKTTSSSTRNTVAARFRAVASEASSQSSGKTTYYCTDPYGYCDSNTLAYTLPSSNLIANCDIYYSYLPALTSSCHAQDQATTTLHEFTHAPAVYSPGTDDYAYGYRASTALSASQALLNADTYALFANGTPPPPPSPLHIHFQMLDTNNGYSREP
What is the function of this protein?
Secreted metalloproteinase that allows assimilation of proteinaceous substrates.  Shows high activities on basic nuclear substrates such as histone and protamine.  May be involved in virulence (By similarity).
What are the official names of this protein?
Neutral protease 2 homolog AFUA_4G13750, Deuterolysin AFUA_4G13750.
What is the protein family that this protein belongs to?
Belongs to the peptidase M35 family.
What are the subcellular locations of this protein?
Secreted.
Protein: YPED_ECOLI
Sequence: MNLIIILVWHSMKHSKGYVLEAQDDELSR
What are the official names of this protein?
Protein YpeD.
Protein: RL3_PSEPF
Sequence: MTIGVVGRKAGMTRIFTEEGVSIPVTVIEIEPNRVTQFKTEETDGYRAVQVTVGERRASRVTAAQAGHFAKANVAAGRTVMEFRLEEGEYQAGDLINAEIFAAGQLVDVTGQSKGKGFQGTIKRWNFRGQDNTHGNSVSHRVPGSIGQCQTPGRVFKGKKMSGHMGAERVTVQSLEVVRVDAERNLLLVKGAVPGATGGNLVVRPAAKARG
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: STX10_HUMAN
Sequence: MSLEDPFFVVRGEVQKAVNTARGLYQRWCELLQESAAVGREELDWTTNELRNGLRSIEWDLEDLEETIGIVEANPGKFKLPAGDLQERKVFVERMREAVQEMKDHMVSPTAVAFLERNNREILAGKPAAQKSPSDLLDASAVSATSRYIEEQQATQQLIMDEQDQQLEMVSGSIQVLKHMSGRVGEELDEQGIMLDAFAQEMDHTQSRMDGVLRKLAKVSHMTSDRRQWCAIAVLVGVLLLVLILLFSL
What is the function of this protein?
SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network.
What are the official names of this protein?
Syntaxin-10, Syn10.
What is the protein family that this protein belongs to?
Belongs to the syntaxin family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type IV membrane protein.
Protein: GCSH_XANCP
Sequence: MSEIPGDLKFLKSHEWARVEGNGRVTVGISDHAQGLLGDLVYVELPAVGDTVQAGNGAAVVESVKAASDVYSPVTGTVVEVNASLSDKPETINEDAYGEGWIFVVEIDDKEQLNELLAPDDYAELLEDDAH
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: THIM_BREBN
Sequence: MILETIGQLLIKVREENPLVHNITNVVVTNFTANGLLALGASPVMAYAKQEVADMAKIAGALVLNIGTLNEHEIEAMLIAGKSANQHGVPVLFDPVGAGATSYRTETSQRLAQELDLAFIRGNAAEVANVIGERWEIKGVDAKEAGGDVEDLARAAAKKLRTIVAITGKVDVISDGEKTYSIHNGHPILTKVTGTGCLLTSVMGAFAAIAKDKLIAGAAALVCYGVAAQLAAEKAAEVGPGSFQIEFLNALHNLTAEDVRRLGYIEKRE
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: FENR_BUCAP
Sequence: MNPWINANVLKVHKWTQNLFSLILNAEIAPFQAGQFTKLALNEENINFSNNVKKKKIQRAYSFVNAPSNKNLEIYIVRILNGKLSNLLYNLKSGDNLFIKEKSFGFFTLDEIPNCKTLWMFATGTGIGPYCSILQEYKNINRFKNIILIHAVRYQNELTYLPLMKQLYKSYNGKLKIETIVSREKNHNSLYGRIPLLLQNQILEKKIGLKINRNDSHVMLCGNPAMVKDTYLFLQKDRCMQKNLRRKHGHITMENYW
What is the function of this protein?
Transports electrons between flavodoxin or ferredoxin and NADPH.
What are the official names of this protein?
Flavodoxin/ferredoxin--NADP reductase, Ferredoxin (flavodoxin):NADP(+) oxidoreductase, Ferredoxin--NADP reductase, FNR, Flavodoxin--NADP reductase, FLDR.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_SINMW
Sequence: MQTSLNRALNGLRVSRETVEKLEHFASLFQKWARSINLVAPSTLDDLWRRHILDSIQLFQLSPAPKTWVDLGSGGGFPGVITAICLSETESGWVHLVESNNKKAAFLRVALRETAARGTVHPIRIEEAPAEIPTCDAISARALSDLSQLLEYCAPWMTVEASRTIAFFHKGRDYQLEIDKAVSRFQFDLVKHASVVEPDSVVLEVANLSRRTK
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRP28_BOTFB
Sequence: MASNGYSNSADAVPPPPSDNDGRPPSPPPPPPDSFVPPPPPSSLAPPPPPSSDLPPPPPSELLPPPPEPKKKKGWGAPKPGPLSIEDILKKKKEADEAAAKAKFLSKAAREKLALETRAKEVEEQKRKREAEQDNRISIGSVNGNGNGYGSAANGPDGYERSYQQENGRRESSFVPTGPRAMRNSQQSRSSSDKPNDMEPPPKPAKSAAAGTGKASVAGEKRPANAEDLQAALIKTRYMGAETNQSTFSAKKKRRRTTEKKFNFEWNAEEDTSPDYNPIYQNRAEAGLYGRGRLGGFAEDEGATLKYAKALEERDAEAGGARAREIVEMERRRKEDAGRNSLDKHWSEKKLEHMRERDWRIFKEDFNISTKGGAIPNPMRNWSESKLPKRLLDVIHQVGYDEPSAVQRAAIPIALQARDLIGVAVTGSGKTAAFLLPLLVYISELPPLNEFTKNDGPYAIILAPTRELAQQIEVEAKKFATPLGFTCVSIVGGHSLEEQSYNLRNGAEIIIATPGRLVDCIERRVLVLGQCCYIIMDEADRMIDLGFEESVNKILDALPVSNEKPDTDDAEDAQAMSRHLGGKDRYRQTMMYTATMPPAVEKIAKKYLRRPAIVTIGNIGEAVETVEQRVEFVAGEDKRKKRLNEILASGEFAPPIIVFVNIKRNCDAVARDIKHMGFTSVTLHGSKTQEQREAALASVRSGATNVLVATDLAGRGIDVPDVSLVVNFNMATNIESYTHRIGRTGRAGKSGVAITFLGNEDSDTMYDLKQMLTKSSISRCRKS
What is the function of this protein?
ATP-dependent RNA helicase involved in mRNA splicing.  May destabilize the U1/5' splice site duplex to permit an effective competition for the 5' splice site by the U6 snRNA, resulting in the switch between U1 and U6 at the 5' splice site.  May also act to unwind the U4/U6 base-pairing interaction in the U4/U6/U5 snRNP, facilitating the first covalent step of splicing (By similarity).
What are the official names of this protein?
Pre-mRNA-splicing ATP-dependent RNA helicase prp28.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX23/PRP28 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: LETM1_DROME
Sequence: MNALLRHKGRNLRTSHLAQNVYKRFLKSNCCACSSVNVTDEPAKEDELPRRSASTSVLELSRSLGTYRRFQPHANYGYDYSGYGFRHLHTSRTLLETSSSKIDATVKKLKNQQKEKVEEIMKEVANGQAAAVRASSAATATASSEKGQNASATAGSTSATASTTSLAKTADKSVAKPKKPLRTRIWDELVHYYHGFRLLFIDVAICSKLLWRVLNGKTLTRRENKQLQRTTSDLFRLIPFSVFIIVPFMELLLPLFIKFFPGMLPSTFQTSTDRQEKLRQSLSVRLEVAKFLQQTLDQMPVQHKEHSSEEAKQFEAFFTKIRNPTEPVSNDEIIKFAKRFDDEITLDSLSREQLAALCRVLELNTIGTTTLLRFQLRLKLRSLATDDRVIAREGVDSLDLLELQQACKARGMRAYGLTEERLRFQLKEWIDLSLNEQVPPTLLLLSRTMLISDDSITTDKLKETIRVLPDAVGAHTRHAIGESEGKVDNKTKIEIIKEEERKIREEREEEREETIAKRSAIKEEIPAPYVFAEKLSGSQDLLDHKEQSSVSETDKGISSTDVQLLSEALKTLSSDKQLVVEKETIKELKEELADYKEDVEELREVRQVVKEPVRESRAAKLLYNRVNKMISQLDNVLNDLEARQHQIKQAESSDYAASSPTVEPQQMVHIDELVATIRRMKEASDEERFKVVGDLLVKLDADKDGVISVNEITKAVQSIDREATNIDKKQLEEFTELLSKLASRRRHEEIVHIDDLMNNIKVLKETSDEARLKHIEAVLEKFDADKDGVVTVNDIRKVLESIGRDNIKLSDKAIEELISLLDKEQVLQAEQKIEKAIAKSMKEAEKLKSEVDKADKDLSKLVNDIHDSAKEIQDIANEMRDKEETVPDKAKELKAEPAFKDTAKTLKDNAKDLDDLAKDPKSDPKSPTKASTGSGPAGLSGGGPSSGSSGIATGSTTESALREAAERQMEKILPSTDIGLPPTIQTPSQPPTSKKATATASTLSTTITAKKLL
What is the function of this protein?
Mitochondrial proton/calcium antiporter that mediates proton-dependent calcium efflux from mitochondrion.
What are the official names of this protein?
Mitochondrial proton/calcium exchanger protein, Leucine zipper-EF-hand-containing transmembrane protein 1, dLetm1.
What is the protein family that this protein belongs to?
Belongs to the LETM1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: PSME1_BOVIN
Sequence: MATLRVLPEAQAKVDVFREDLCTKTENLLGSYFPKKISELDAFLKEPDLNEANLSNLKAPLDIPVPDPVKEKEKEERRKQQEKEDKDEKKKGEDEDKGPPCGPVGCNEKIVVLLQRVKPEIKDVIEKLNLVTTWLQLQIPRIEDGNNFGVAVQEKVFELMTALHTKLEGFHTQISKYFSERGDAVTKAAKQPHVGDYRQLVHELDEAEYRDIRLMVMEIRNAYAVLYDIILKNFEKLKKPRGETKGMIY
What is the function of this protein?
Implicated in immunoproteasome assembly and required for efficient antigen processing.  The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.
What are the official names of this protein?
Proteasome activator complex subunit 1, Proteasome activator 28 subunit alpha, PA28a, PA28alpha.
What is the protein family that this protein belongs to?
Belongs to the PA28 family.
Protein: HARS1_DANRE
Sequence: MADKAQLQEAIKTQGEVVRKLKSEKASKEQIDEEVARLLQLKAQLGGDEGKHVFVLKTAKGTRDYNPKQMAIREKVFNIIINCFKRHGAETIDSPVFELKETLTGKYGEDSKLIYDLKDQGGELLSLRYDLTVPFARYLAMNKITNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAGQYDAMIPDAECLKLVYEILSELDLGDFRIKVNDRRILDGMFAICGVPDEKFRTICSTVDKLDKLAWEEVKKEMVNEKGLSEEVADRIRDYVSMQGGKDLAERLLQDPKLSQSKQACAGITDMKLLFSYLELFQITDKVVFDLSLARGLDYYTGVIYEAILTQANPAPASTPAEQNGAEDAGVSVGSVAGGGRYDGLVGMFDPKGRKVPCVGVSIGIERVFSIMEQKAELSSEKVRTTETQVLVASAQKNLLEERLKLTAELWNAGIKAEVLYKKNPKLLSQLQHCEDTGIPLVAILGEQELKDGVVKLRNVASREEVDVPRAELVDEVKKRTS
What is the function of this protein?
Catalyzes the aminoacylation of histidyl-tRNA.
What are the official names of this protein?
Histidine--tRNA ligase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
[Isoform 1]: Cytoplasm. SUBCELLULAR LOCATION: [Isoform 2]: Mitochondrion.
Protein: RL27_NITOC
Sequence: MAHKKAGGSSRNGRDSESKRLGVKRFGDQQVLAGNILVRQRGTPFLAGINVGTGRDHTLYAKAAGKVQFVRRGPKSRTYVDVVTN
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: NU5C_NASOF
Sequence: MEHTYEYSWIIPFIPLPVPILLGVGLLLFPTATKNLRRMWTFLSIFLLSIIMIFSLYLSIQQIFLSCIHQNVWSWTINNEFSFEFGYFIDPLTSIMSILITTVGILVLIYSDNYMSHDQGYLRFFAYMGFFNTSMLGLVTSSNLIQVYFFWELVGMCSYLLIGFWFTRPIAANACQKAFVTNRVGDFGLLLGILGLYWITGSFEFQDLFEIFNNLVLNNRVNLLFLTLCAFLLFVGPIAKSAQFPLHVWLPDAMEGPTPISALIHAATMVAAGIFLVARLLPLFIVIPSIMYIISLIGIITVLLGATLALAQKDIKRGLAYSTMSQLGYMMLALGMGSYRSALFHLITHAYSKALLFLGSGSIIHSMEAIVGYSPDKSQNMILMGGLTKHVPITKIAFLVGTLSLCGIPPLACFWSKDEILNDSLLFSPIFAIIAFSTAGLTAFYMFRIYLLTFEGHLNTYFINYSGKKSSSVYSISLWGKEEEKKLNRNFGLVPLLTMNNTKRASFFCKKTYKISNNVRNQTFITVENFGLNPRTFYYPHESDNTILFPMLVLLLFTLFIGAIGIPFTQEGLDFDILSKLFTPSINLLHKNSESFVDWYEFLRNATFSVSIAFFGIFIAYYLYKPFYSSLLNLTLLNSFQKLNSKRIRWEKLINFVYNWSYNRGYIDAFFKTSLIESIRRLAKQTNFFDKRIIDGITNGVGITSFFVGEVTKYIGGSRISSYLFLYLSYVLIFLMILFFFYFEKF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 5, chloroplastic, NAD(P)H dehydrogenase subunit 5, NADH-plastoquinone oxidoreductase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ATPA_BACLD
Sequence: MSIKAEEISTLIKQQIENYQSEIEVHDVGTVIQVGDGIARVHGLDNCMAGELVEFSNGVLGLAQNLEESNVGIVILGPYKDIREGDEVKRTGRIMEVPVGEELLGRVVNPLGQPVDGMGPVLTSKTRPIESPAPGVMDRKSVHEPLQTGIKSIDALIPIGRGQRELIIGDRQTGKTSIAIDTILNQKDQDMICIYVAIGQKESTVRGVVETLRKHGALDYTIVVTASASQPAPLLYLAPYAGVAMGEEFMYNGKHVLVVYDDLSKQATAYRELSLLLRRPPGREAFPGDVFYLHSRLLERAAKLSDAKGGGSLTALPFVETQAGDISAYIPTNVISITDGQIFLQSDLFFSGVRPAVNPGLSVSRVGGSAQIKAMKKVAGTLRLDLASYRELEAFAQFGSDLDKATQAKLNRGARTVEVLKQDLHKPLRVEKQVAILYALTRGFLDDVPVEDIKRFEEELFMYLDQNHKDLLDSIAQTGNLPADEDMKGAIEGFKRTFAPSN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MCTE_CERS1
Sequence: MAHQAHPFRSVLYIPGSKERALEKAQGLAADAIIFDLEDAVAHDEKIHARALLKTTLETVDYGHRFRIVRVNGMDTEWGRADLEAFAEAKADAILIPKVSRAADLEAVAALVPDLPLWAMMETAQGMLNAAEIAAHPRLTGMVMGTNDLAKELGSRYRPDRLAMQAGLGLCLLAARAHGLTIVDGVYNAFKDEEGLRAECEQGRDMGFDGKTLIHPAQLEIANAVFSPSPAEIELANRQIAAFEEAERHGQGVAVVDGKIVENLHIVTARQTLAKAEAIAAFRAS
What is the function of this protein?
Catalyzes the hydrolysis of (3S)-malyl-CoA to (3S)-malate and free CoA.  Inactive towards beta-methylmalyl-CoA and other CoA esters (By similarity).
What are the official names of this protein?
(3S)-malyl-CoA thioesterase, (3S)-malyl-CoA thiolesterase.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family.
Protein: IOLE_CLOB8
Sequence: MLNTEKVKLGICPIGWTNDDMPDLGKENTFEQAVSEMALAGFKGTEVGNKYPKDVNVLKKALDLRNLQIASAWFSSFLTTKPYEETEKEFIAHRDFLHEMGAKVIVVSEQGHSIQGEMDTPICEGKYYFNEEEWKLLADGLNKLGRLAEDKGMKIVYHHHMGTGVQTTDEIDKLMSMTDESLVYLLFDTGHLVYSGENPIAILNKYANRIKHVHLKDIRADVLEKVKKEKMSFLMGVREGSFTVPGDGCIDFEPIFKILDENNYEGWILVEAEQDPAIANPFEYAMKARKYIKEKTGF
What is the function of this protein?
Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol).
What are the official names of this protein?
Inosose dehydratase, 2-keto-myo-inositol dehydratase, 2KMI dehydratase.
What is the protein family that this protein belongs to?
Belongs to the IolE/MocC family.
Protein: LGT_HELPS
Sequence: MNAWNTIYDQFNPIAFSLGSIEVHWYGLAYACAIVTAFYMALRMIQKDPKRFPIERKEFESYFLWAELGIVLGARVGYILIYEPNSSYYLTHFWQIFNPFDSNGDFVGIRGMSYHGGLVGFLIASYLYSRKDLKKLLIYLDLIAISLPLGYVFGRIGNFLNQELVGRVVPKDSHLGQIIGIMVGNELRYPSQLIEAFLEGVIVFLMVLWAKKHTKTHGLLIVVYGLGYSLMRFIAEFYREPDSQMGVYFLNLSMGQILSLLMVIVSLGILLYATKNSKKIKGNQ
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SENX3_MYCTU
Sequence: MTVFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMPLGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGEDVEFDLSPRKRSATGRSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLAEALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSEAISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRRRGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTIRVWSKPGTGSTFTLALPALIEAYHDDERPEQAREPELRSNRSQREEELSR
What is the function of this protein?
Member of the two-component regulatory system SenX3/RegX3 involved in stress response (PubMed:12777483, PubMed:21698211, PubMed:35980355).  Autophosphorylates, and then transfers the phosphate group to RegX3 (By similarity).  The system is involved in phosphate starvation response (PubMed:28698272).  Plays a role in modulating expression of aerobic response and in the regulation of response to hypoxia (PubMed:21698211, PubMed:35980355).  Involved in virulence (PubMed:12777483, PubMed:25333974).  SenX3 is a key regulator of mycobacterial replication in response to oxygen, nitric oxide (NO) and carbon monoxide (CO), and acts as an O(2) sensor that plays an important role in the reactivation of growth in response to the restoration of aerobic conditions (PubMed:25333974).
What are the official names of this protein?
Sensor-like histidine kinase SenX3.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.