PharMolix/UniProtQA huggingface dataset:
Protein: G6PI2_CLACO
Sequence: MATPSLISETEAWKDLKAHLEGIKRTHLRELMGDTERCQSMMVEFDNIFLDYSRQQASPDTINKLFKLADAAHLKRKIDRMYNGDHINSTENRSVLHVALRAPRNSAICSDGKNVVPDVWSVLDKIKDFSERVRNGSWVGATGKELKDVIAVGIGGSFLGPLFVHTALQTDPEASKNAIGRELRFLANVDPIDAAKNISGLNPETTLVVVVSKTFTTAETMLNARTLREWISSALGASAVAKHMVAVSTNLPLVEKFGIDPNNAFAFWDWVGGRYSVCSAVGVLPLSLQYGFAVVEKFLQGAHSIDQHFSSAPFEKNIPVLLGLLSVWNVSFLGYPARAILPYSQALEKLAPHIQQVSMESNGKGVSVDGLPLPFESGEIDFGEPGTNGQHSFYQLIHQGRVIPCDFIGVVKSQQPVYLKGEVVNNHDELMSNFFAQPDALAYGKTPEQLKKENVSEHLIPHKTFNGNRPSLSILLPTLDAYRIGQLLAVYEHRVAVQGFVWGINSFDQWGVELGKSLATQVRKQLHASRVKGEAVEEGFNFSTKTLLTRYLEASSDVPADPSTLLPKI
What are the official names of this protein?
Glucose-6-phosphate isomerase, cytosolic 2, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPR_ECOLU
Sequence: MAQQSPYSAAMAEQRHQEWLRFVDLLKNAYQNDLHLPLLNLMLTPDEREALGTRVRIVEELLRGEMSQRELKNELGAGIATITRGSNSLKAAPVELRQWLEEVLLKDH
What is the function of this protein?
This protein is an aporepressor.  When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription.  The complex also regulates trp repressor biosynthesis by binding to its regulatory region.
What are the official names of this protein?
Trp operon repressor.
What is the protein family that this protein belongs to?
Belongs to the TrpR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPT5_ARATH
Sequence: MVGSLEVSKPPEHKVESKIVIADEEEEDENDSPIEEVRLTVPITDDPSLPVLTFRTWFLGMVSCVVLAFVNNFFGYRSNPLTVSSVVAQIITLPLGKLMATTLPTTKLRLPGTNWSCSLNPGPFNMKEHVLITIFANTGAGGAYATSILTIVKAFYHRNLNPAAAMLLVQTTQLLGYGWAGMFRKYLVDSPYMWWPANLVQVSLFRALHEKEEKREGKQTKLRFFLIVFFLSFTYYIVPGYLFPSISYLSFVCWIWTRSVTAQQIGSGLHGLGIGSFGLDWSTVAGFLGSPLAVPFFAIANSFGGFIIFFYIILPIFYWSNAYEAKKFPFYTSHPFDHTGQRYNTTRILNQKTFNIDLPAYESYSKLYLSILFALIYGLSFGTLTATISHVALFDGKFIWELWKKATLTTKDKFGDVHTRLMKKNYKEVPQWWFVAVLAASFVLALYACEGFGKQLQLPWWGLLLACAIAFTFTLPIGVILATTNQRMGLNVISELIIGFLYPGKPLANVAFKTYGSVSIAQALYFVGDFKLGHYMKIPPRSMFIVQLVATIVASTVSFGTTWWLLSSVENICNTDMLPKSSPWTCPGDVVFYNASIIWGIIGPGRMFTSKGIYPGMNWFFLIGFLAPVPVWFFARKFPEKKWIHQIHIPLIFSGANVMPMAKAVHYWSWFAVGIVFNYYIFRRYKGWWARHNYILSAALDAGTAVMGVLIYFALQNNNISLPDWWGNENTDHCPLANCPTEKGIVAKGCPVF
What is the function of this protein?
Involved in the translocation of tetra- and pentapeptides across the cellular membrane in an energy-dependent manner.
What are the official names of this protein?
Oligopeptide transporter 5, AtOPT5.
What is the protein family that this protein belongs to?
Belongs to the oligopeptide OPT transporter (TC 2.A.67.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: F16PA_SALNS
Sequence: MKTLGEFIVEKQHEFSQATGELTALLSAIKLGAKIIHRDINKAGLVDILGASGAENVQGEVQQKLDLFANEKLKAALKARDIVAGIASEEEDEIVVFEGCEHAKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRVTPVGTPVTEEDFLQPGNKQVAAGYVVYGSSTMLVYTTGCGVHAFTYDPSLGVFCLCQERMRFPEKGKTYSINEGNYIKFPNGVKKYIKFCQEEDSSTSRPYTSRYIGSLVADFHRNLLKGGIYLYPSTASHPQGKLRLLYECNPMAFLAEQAGGKASDGKERILDIIPESLHQRRSFFVGNRHMVDDVERFIREYPDA
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOH_CITK8
Sequence: MNDIWWQTEGQGNCHLVLLHGWGLNAEVWNCIREELSAHFTLHLVDLPGFGRSQGFGAMSLEQMAKHVLKQAPDKAVWLGWSLGGLVASQVALTHPERVQALVTVASSPCFSAREAWPGIKPDILAGFQQQLSEDFQRTVERFLALQTLGTETARQDARTLKSAVLALPMPEVAVLNGGLEILKTADLREPLKSLTMPFLRLYGYLDGLVPRKVVPMLDAAWPESESQVFAKAAHAPFISHPGEFCQALMALKQKI
What is the function of this protein?
The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete.  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.
What are the official names of this protein?
Pimeloyl-[acyl-carrier protein] methyl ester esterase, Biotin synthesis protein BioH, Carboxylesterase BioH.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG181_MONPV
Sequence: MDGVIVYCLNALVKHGEEINHIKNDFMIKPCCERVCEKVKNVHIGGQSKNNTVIADLPYLDNAVSDVCKSIYKKNVSRISRFANLIKIDDDDKTPTGVYNYFKPKDAIPVIISIGKDKDVCELLISSDKACACIKLNLYKVAILPMDVSFFTKGNASLIILLFDFSIDAAPLLRSVTDNNVIISRHQRLHDELPSSNWFKFYISIKSDYCSILYMVVDGSMMYAIADNRTHAIISKNILDNTTINDECRCCYSEPQIRILDRDEMLNGSSCYMNRHCIMMNLPDVGEFGSSMLGKYEPDMIKIALSVAGNLIRNRDYIPGRRGYSYYVYGIASR
What are the official names of this protein?
Protein OPG181.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG181 family.
Protein: 3CP1_STRS9
Sequence: CLGIGSCNDFAGCGYAVVCFW
What is the function of this protein?
Active against HIV-1 virus in vitro.
What are the official names of this protein?
Tricyclic peptide RP 71955.
Protein: SYV_PASMU
Sequence: MTQNFEMADRFTPSAVEQALYKHWEESGYFKPSEDTSKPSYSIAIPPPNVTGSLHMGHAFQQTLMDILIRFNRMEGHNTLWQTGTDHAGIATQMVVERKIAAEEGKTRHDYGREAFIDKIWDWKAYSGGTISQQMRRLGNSIDWERERFTMDEGLSDAVKEVFVRLHEEGLIYRGKRLVNWDPKLHTAISDLEVENKESKGSLWHFRYPLANGAKTADGKDYLVVATTRPETMLGDTAVAVHPEDERYQSLIGKTVVLPLANREIPIIADDYVDREFGTGVVKITPAHDFNDYEVGKRHQLPMVNVMTLNADIRAEAEIIGSDGKILESYTALIPTKYQGMERFAARKQIVADFEELGLLDEIKPHDLKVPYGDRGGVPIEPMLTDQWYVSVKPLAEVAVKAVEDGEIQFVPKQYENLYFSWMRDIQDWCISRQLWWGHRIPAWYDEQGNVYVARDEAEVRAKHNLPADLALKQDEDVLDTWFSSGLWTFSTLGWPKQTPDLKMFHSTDVLITGFDIIFFWVARMIMFTMHFVKDENGKPQVPFKTVYVTGLIRDEQGQKMSKSKGNVIDPLDMIDGIDLESLLEKRTGNMMQPQLAEKIAKATIKAFPEGIAEHGTDALRFTLTALATNGRDINWDMKRLEGYRNFCNKLWNASRFVLTNDKLDLSEGSVEYSVADRWIQSEFNRTVEAFRNALAQFRFDLCATALYEFTWNQFCDWYLELTKPVLVNGSVAQKRGASQTLINVLEKLLRLTHPVMPFITEEIWHKVKAFAGVSGDTIMLQAFPQFEQSALDYQAEAEINWMKEVIVAVRNIRAESNIPPSKGLDLLLRNLSEADQNALENNRTLIQAMAKLDAIRVLEAGEDAPLSVAKLVNNAELLVPMAGFINKEAELARLNKEIEKYQGEIQRIENKLANEAFVAKAPPAVIEKERAKMAEYAEGLNKLKQQYLAIEAL
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THSA_SULTO
Sequence: MANAPVLLLKEGTQRSSGRDALKNNILAAVTLAEMLKSSLGPRGLDKMLIDSFGDVTITNDGATIVKEMEIQHPAAKLLVEAAKAQDAEVGDGTTSAVVLAGLLLDKADDLLDQNIHPTIIIEGYKKALNKSLEIIDQLATKIDVSNLNSLATRDQLKKIVYTTMSSKFIAGGEEMDKIMNMVIDAVSIVAEPLPEGGYNVPLDLIKIDKKKGGSIEDSMLVHGLVLDKEVVHPGMPRRVEKAKIAVLDAALEVEKPEISAKISITSPEQIKAFLDEEAKYLKDMVDKLASIGANVVICQKGIDDVAQHFLAKKGILAVRRVKRSDIEKLEKALGARIISSIKDATPEDLGYAELVEERRVGNDKMVFIEGAKNPKAVNILLRGSNDMALDEAERSINDALHSLRNVLMKPMIVAGGGAVETELALRLREYARSVGGKEQLAIEKFAEALEEIPMILAETAGMEPIQTLMDLRAKHAKGLINAGVDVMNGKIADDMLALNVLEPVRVKAQVLKSAVEAATAILKIDDLIAAAPLKSGEKKGEKKEGGEEEKSSTPSSLE
What is the function of this protein?
Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity.
What are the official names of this protein?
Thermosome subunit alpha, Chaperonin subunit alpha, Thermosome subunit 1.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
Protein: PSBE_DRIGR
Sequence: MSGSTGERSFADIITSIRYWVIHSITIPSLFIAGWLFVSTGLAYDVFGSPRPNEYFTESRQGIPLITGRFDPLEQLDEFSRSF
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit alpha, PSII reaction center subunit V.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RPOB_LIMRD
Sequence: MAGHLVKYGKHRTRRSYSRIKEVLELPNLIEIQTDSYNWFMEKGLREMFDDIMPIDDFQGKLSLEFVDYQLLEPKYTVDEAREHDANYSAPLHVTLRLTNHETGEIKSQDVFFGDFPLMTDQGTFIINGAERVIVSQLVRSPGVYYSEENDKNGRPNYGATFIPNRGAWLEYETDAKNVSYVRIDRTRKLPMTELIRALGFGSDDEIIDMFGGDSETLSLTLDKDVHKNAEDSRVEEALKDIYERLRPGEPKTADSARSLLTARFFDPKRYDMAPVGRYKTNKKLMLKYRLLGQTLAETLADPDTGEVLAQKGDTVTKELLNKLEPYLDRDDFKTITYTPSDEAVVTEPVKLQKILVYSKNDPDRVVPIIGNGHIPLEYKHIEPADILASLNYFFNLQEGIGSTDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDPDTVTPQQLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVRDVHYTHYGRMCPIETPEGPNIGLINSLSSYARVNKYGFIETPYRRVSWKDHKVTDKIDYLTADEEDNFIIAQANTPLNDDGSFVDDQVMARDKDDYIETSVENIDYMDVSPKQVVSVASACIPFLENDDSNRALMGANMQRQAVPLINPHAPLVSTGIDYKAAHDSGVAMIAKKPGTVEYVDAREVRVREEDGTLDTYKLMKFRRSNGGKNYNQRPIVKVGEHVDADDVLADGPSMEQGELALGQNPLIAFMTWQGYNFEDAIAINERLVKDDVYTSIHIESYESEARETKLGPEEMTREIPNVGDDALKDLDENGIVRVGAEVHDGDILVGKVTPKGMTELSAEERLLHAIFGEKSREVRDTSLRVPHGGGGIIQDVKVFTRENGDELSPGVNTMVRVYIAQKRKIQVGDKMSGRHGNKGTVSIVVPEEDMPYMPDGTPIDIMLSPMGVPSRMNIGQLLELHLGMAARRLGIHMATPVFDGASDKDVWDAVRESGFPEDGKTILYDGRTGEPFENRIAVGSMHYLKLAHMVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVRTYDAIINGQPIPKPGVPESFRVLVKELQALGLDMKVLDGNNKEIQLKNMDEDDDEVVNVDALAKYAEEHKADDKKNEEENKSEATSTTTDDKTNQN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: ACCD_CRUWA
Sequence: MEKSWFNLMFSKGELESRGELSKAMDSFAPSEKTTISQDRFIYDMDKNFYGWGERSSYSNNVDLLVSSKDIRNFISDDTFFVRDSNKNSYSIYFDIKKKFFEIDNDFSDLEIFFYNYCSSSYLNNRSKGDNDLHYDPYIKDTKYNCTNHINSCIDSYFRSHICIDSNFLSNSKNSNESYIYNFICSESGKIRESKNYKIRTNRNRSNLISSKDFDITQNYNQLWIQCDNCYGLMYKKVKMNVCEQCGHYLKMSSSERIELSIDPGTWNPMDEDMVSADPIKFHSKEEPYKNRIDSAQKTTGLTDAVQTGTGQLNGIPVALGVMDFQFMGGSMGSVVGEKITRLIEYATNQCLPLILVCSSGGARMQEGSLSLMQMAKISSVLCDYQSSKKLFYISILTSPTTGGVTASFGMLGDIIIAEPYAYIAFAGKRVIEQTLKKAVPDGSQAAESLLRKGLLDAIVPRNLLKGVLRELFQLHAFFPLNKN
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: NMUR1_HUMAN
Sequence: MTPLCLNCSVLPGDLYPGGARNPMACNGSAARGHFDPEDLNLTDEALRLKYLGPQQTELFMPICATYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYEMWHNYPFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRRVLGAVWGLAMLCSLPNTSLHGIRQLHVPCRGPVPDSAVCMLVRPRALYNMVVQTTALLFFCLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTKMLFVLVVVFGICWAPFHADRVMWSVVSQWTDGLHLAFQHVHVISGIFFYLGSAANPVLYSLMSSRFRETFQEALCLGACCHRLRPRHSSHSLSRMTTGSTLCDVGSLGSWVHPLAGNDGPEAQQETDPS
What is the function of this protein?
Receptor for the neuromedin-U and neuromedin-S neuropeptides.
What are the official names of this protein?
Neuromedin-U receptor 1, NMU-R1, G-protein coupled receptor 66, G-protein coupled receptor FM-3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ISPD_SODGM
Sequence: MIALAGQTPDVIAILPAAGIGSRMQTALPKQYLTIGNKTLLEHAIDALLCHPCISEAVVAISAEDRWFYQLPVAADPRVRVVTGGSVRADSVMAALRCASAASWVLVHDAARPCLHQDDLRRLLVITAHTEVGGLLATPVRDTMKRAHTGSDIIAATVEREDLWHALTPQLFARDLLITCLERALAEGATVTDEASALEYCGYAPLLVPGRVDNIKVTRPEDLALARFFFSQLANTESV
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: RIBL_METAR
Sequence: MVRRVVATGTFDILHPGHVLYLCEARKHGDELWVIVARESTIKHKRKPLIPEEQRLFMVQSLKCVDHAVLGSETDMFEPIRQIQPEVIAIGFNQHWNENELKKQLAERGIKAEIVRIQTSDHSPYASSRTIRQKIKESDP
What is the function of this protein?
Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
What are the official names of this protein?
FAD synthase, FMN adenylyltransferase, Flavin adenine dinucleotide synthase.
What is the protein family that this protein belongs to?
Belongs to the archaeal FAD synthase family.
Protein: PDXY_BURO1
Sequence: MKNVLSIQSHVIYGHAGNSAAVFPMQRLGINVWPLNTVQLSNHMQYGHWAGSAIDAAKMEQLVDGIAAIGVLKRCDAVLSGFLGSPPQARAAVEIVRTVKAMNPNAWYFCDPAMGQTGGIRPEPGVEEFIVEEVPALADGMSPNHTELQKLAGRRIETVAEAVDACRALIRRGPQIILVKHLHDRNSPADRFNMLAVTETEAWIGQRPLYAFPRHPVGVGDLTSAIFVACRLRGDSVRAAFEHTLAAVHAVVKATYDARRYELELVAAQDEIARPSEWFGAWVTDA
What is the function of this protein?
Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP).  Catalyzes the phosphorylation of pyridoxal to PLP.
What are the official names of this protein?
Pyridoxal kinase PdxY, PL kinase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxine kinase family. PdxY subfamily.
Protein: PLSX_CHRVO
Sequence: MTITVAVDAMGGDVGLKVTVPASIQFLQDHPDTHLILVGDQPALEAELALHDGAVRERILIQHATQVVGMDEAPQLALKNKKDSSMRVAINLVKEGKAQAAVSAGNTGALMATARFVLKTIPGIDRPAIAKLLPNVKGTSCVLDLGANVDCTPEQLLQFGIMGSELMACLQGKANPSVGLLNIGSEDIKGNDNIKKTAELLRQSELHFYGNVEGDDICKGTTDVVVCDGFTGNVALKTAEGLAHMFAVFLREEFGRSWWTRLCALAALPVLALFKKRIDPRRYNGASLLGLRGIVVKSHGSADVTGFRYALAQACEEAGSDVIAHIADRVAKQLDNLKQSEAEAN
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: C6_ORYSJ
Sequence: MAPSKSTAAAGVLLVLLVAAAGGGAEAAATTCVASLLELSPCLPFFKDKAATAAPEGCCAGLSSIVKGEAVCLCHIVNHTLERAIGVDIPVDRAFALLRDVCRLSPPADIISTCANEKGGVPPLYSCPAPSA
What is the function of this protein?
Lipid-transfer proteins that possesses lipid-binding activity in vitro.  Involved in the development of lipidic orbicules/Ubisch bodies and pollen exine during anther development (PubMed:20610705).  May be regulated by the transcription factor UDT1 in developing anthers and play a role in tapetum development (PubMed:16141453).  Positively regulated by the transcription factor TDR in developing anthers and may play a role in tapetum programmed cell death (PCD) (PubMed:17138695).
What are the official names of this protein?
Non-specific lipid-transfer protein C6, OsC6.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space.
Protein: RS14_OCEIH
Sequence: MAKKSKIAKERKRQQMVEKYAELRRELKAKGDYEAIRKLPRDSSPTRLTGRCEVTGRPRGYMRQFKMSRIAFREYAHKGQIPGVKKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: VIRL_HYPVG
Sequence: MSSQLENEASFEATTLGFLWRQFTRPKPLPTGITLAGQVAIVTGSNVGLGFSASRQLLQLGLSHLIMGVRSQAKGDVAAAQLRTDFPFATISVWIVDMESYDSVCAFASRCESLDRIDIVILNAGLIKTPYTVVRATGNEVTLQVNYLSTALLTILLLPILKAKKRVDCSWSPVISIVGSDLMYENEVELEGPVLPQFQQEETFSQFSWYGKSKLLQTMFISKIAEFVNPHDVLVNVSNPGMTGGTDFFRGYPALMMKLIAVGQWILARPVDMAATTYLDAVLVQGEKSHGSFTSDWTIKPYPKIWYTPEGQQLRERLWEETMEELNFVGASKIVNDLKRS
What is the function of this protein?
Short chain dehydrogenase; part of the gene cluster that mediates the biosynthesis of virensols and trichoxide, fungal natural products that contain or are derived from a salicylaldehyde core (PubMed:31790246).  The pathway begins with the synthesis of the reduced chain in virensol C by the highly reducing polyketide synthase virA via condensation of one acetate and 8 malonate units (PubMed:31790246).  VirA has interesting programming rules since the first 2 ketides are fully reduced, the 3 following ketides undergo beta-dehydration, and the last 3 ketides are only reduced to beta-hydroxys to yield the trihydroxy portion (PubMed:31790246).  The production of aldehyde virensol C by virA alone is surprising, since virA does not contain a reductase (R) domain that is typically associated with reductive product release in HRPKS (PubMed:31790246).  The cupin-domain enzyme virC is involved in enhancing virA product turnover (PubMed:31790246).  The short-chain dehydrogenase virB then oxidizes the C-7 alcohol of virensol C to a ketone, yielding virensol D (PubMed:31790246).  Virensol D is further transformed to salicylaldehyde 5-deoxyaurocitrin by the short-chain dehydrogenase virD (PubMed:31790246).  VirD catalyzes the dehydrogenation of C-3 to form the beta-ketone aldehyde, which is followed by the generation of the nucleophilic C-2 that is required for the intramolecular aldol condensation between C-2 and C-7, itself followed by dehydration and aromatization which leads to salicylaldehyde 5-deoxyaurocitrin (PubMed:31790246).  While the dehydrogenation of virensol D is definitely catalyzed by virD, the aldol condensation and dehydration may be uncatalyzed or assisted by virD (PubMed:31790246).  The short chain dehydrogenase virG then converts salicylaldehyde 5-deoxyaurocitrin into virensol B which is further hydroxylated by the cytochrome P450 monooxygenase virE to yield the hydroquinone virensol A (PubMed:31790246).  VirI then may oxidize virensol A to form the quinone, while virH performs the epoxidation (PubMed:31790246).  Finally, the two remaining short-chain dehydrogenases, virK and virL, are probably responsible for reducing the ketones to the corresponding alcohols to furnish the epoxycyclohexanol structure in trichoxide (PubMed:31790246).
What are the official names of this protein?
Short chain dehydrogenase virL, Trichoxide biosynthesis protein virL, Virensol biosynthesis cluster protein L.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: THIOM_RAT
Sequence: MAQRLLLRRFLTSVISRKPPQGVWASLTSTSLQTPPYNAGGLTGTPSPARTFHTTRVCSTTFNVQDGPDFQDRVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIEYEVSAVPTVLAIKNGDVVDKFVGIKDEDQLEAFLKKLIG
What is the function of this protein?
Important for the control of mitochondrial reactive oxygen species homeostasis, apoptosis regulation and cell viability.  Possesses a dithiol-reducing activity.
What are the official names of this protein?
Thioredoxin, mitochondrial, MTRX, Mt-Trx, Thioredoxin-2.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RPOZ_MYXXD
Sequence: MARVTVEDCLPLVDNRFALVLLGAKRARQLMAGARPILEQSKNKPPVLSLREVATGRVKFDRDVREALSGKYTGDEPK
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: QOX4_STAAN
Sequence: MSTIMKHTVGFIASIVLTLLAVYVTLYTSLTFHAKLTIIFGFAFVQAGLQLLMFMHLTEGKDGRLQTFKVIFALVITLCFVVGTYWVMQGGHSSHL
What is the function of this protein?
Catalyzes quinol oxidation with the concomitant reduction of oxygen to water.
What are the official names of this protein?
Probable quinol oxidase subunit 4, Quinol oxidase polypeptide IV.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase bacterial subunit 4 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: COBS_LEPBP
Sequence: MKYILLEIRLFFVCMSFLTRIPSPRWIGFQEEWLHHSIKYSPSVGFLLGSLQWFVFLLFQFLFGPTIAFTISLGFLLILTGAFHEDGFSDFCDGIGGGWKREDILRIMKDSRVGSFGAAGISLLLLLKVLGVSETFHQYEIKGLPFTFGSSAQIHLLSVWLYFVTAQSFSRFLSILMMKLLPYAKEEGYAKPMAKEINWPQIYFACIFGVTPFLALVYLHPYFLLSLLCIIPSFVYMFSLMKRWIQGFTGDCLGAVQQVVETCIWISGVFVWISI
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VE7_BPV6
Sequence: MKGQSMILKDLAAELEEVVSPINLDCEEEIETEEVDCPAPFAVEAVCHVCEQVLRLAVVASPDGILQLQQLLLTDSLSFLCTSCSREAFCNRRPQRNGS
What is the function of this protein?
Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle.  Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication.  E7 protein has both transforming and trans-activating activities.  Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes.  Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation.  Also plays a role in the inhibition of both antiviral and antiproliferative functions of host interferon alpha.  Interaction with host TMEM173/STING impairs the ability of TMEM173/STING to sense cytosolic DNA and promote the production of type I interferon (IFN-alpha and IFN-beta).
What are the official names of this protein?
Protein E7.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E7 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=Predominantly found in the host nucleus.
Protein: LSPA_BARBK
Sequence: MTLKSLFFLLLGLIITVLLDQAIKYWITHTMLLGTEIPLFPFISLYHVRNSGIAFSFFSSFSHWGLIALTITIIVFLFWLWKNTELDKALSRFGIVLIIGGAIGNLIDRIRFQAVTDYILFYIDGVFSFAIFNLADTFITLGAISILIDEFCIWIKTKRHLDKSK
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.