PharMolix/UniProtQA huggingface dataset:
Protein: CHLB_SYNP2
Sequence: MKLAYWMYAGPAHIGTLRIASSFKNVHAIMHAPLGDDYFNVMRSMLERERNFTPVTASIVDRNVLARGSQEKVVDNIVRKDQEERPDLIVLTPTCTSSILQEDLENFVARAQLDAQGDVILADVNHYRVNELQAGDRTLQQIVQFYINKARKKGDLATEKTPQPSVNIIGISTLGFHNNHDIRELKTLMAELGISVNLVIPDKASVHDLKKLPQAWFNLVPYRELGLPTAKYLEQEFDQPYVDITPMGVVETARCIRAIQGAINDQGATADYEAFIEEQTLHVSQAAWFSRSIDCQNLTGKKAIVFGDNTHAVAMTKILAREMGIHVVLAGTYCKYDADWFRQEVSEYCDEILISEDHGEIADAIARLEPAAIFGTQMERHVGKRLNIPCGVIAAPIHIQNFPIGYRPFVGYEGTNQIADLVYNSFTLGMEDHLLEIFGGHDTKEVITTTMSASSDLNWTTEAQGQLNKVPGFVRGKVKRNTEKYARAQGLSEISLEVLYAAKESVGA
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (ChlN-ChlB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit B, DPOR subunit B, LI-POR subunit B.
What is the protein family that this protein belongs to?
Belongs to the ChlB/BchB/BchZ family.
Protein: GAG_FSVGA
Sequence: MGQTITTPLSLTLDHWSEVRARAHNQGVEVRKKKWITLCEAEWVMMNVGWPREGTFSLDNISQVEKKIFAPGPYGHPDQVPYITTWRSLATDPPSWVRPFLPPPKPPTSLPQPLSPQPSAPLTSSLYPVLPKSDPPKPPVLPPDPSSPLIDLLTEEPPPYPGGHGPPPSGPRTPTASPIASRLRERRENPAEESQALPLREGPNNRPQYWPFSASDLYNWKSHNPPFSQDPVALTNLIESILVTHQPTWDDCQQLLQALLTGEERQRVLLEARKQVPGEDGRPTQLPNVIDETFPLTRPNWDFATPAGREHLRLYRQLLLAGLRGAARRPTNLAQVKQVVQGKEETPA
What is the function of this protein?
Forms the spherical core of the virion that encapsulates the genomic RNA-nucleocapsid complex.
What are the official names of this protein?
Gag polyprotein, Core polyprotein.
What are the subcellular locations of this protein?
[Gag polyprotein]: Virion. Host cell membrane; Lipid-anchor. SUBCELLULAR LOCATION: [Matrix protein p15]: Virion. SUBCELLULAR LOCATION: [Capsid protein p30]: Virion.
Protein: PHS_RICBR
Sequence: MTITCSLSDKKCIPCEGGVPPLEKKEIDKLLSELQNEWIVNESGHLYKKYKFPDFMQPIEFANKIAALAEQEVHHPDLTISWGACIVEIWTHKIDGLTESDFILAAKIDLLQN
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: URK_SALPA
Sequence: MTDQSHQCVIIGIAGASASGKSLIASTLYRELREQVGDEHIGVIPEDSYYKDQSHLSMEERVKTNYDHPNAMDHSLLFQHLQALKRGSAIELPVYSYVEHTRMQETVRVEPKKVIILEGILLLTDARLREEMNFSIFVDTPLDICLMRRIKRDVNERGRSMDSVMAQYQKTVRPMFLQFIEPSKQYADIIVPCGGKNRIAIDILKAKISQFFE
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPD_ACET2
Sequence: MLKKAISKLVEGKNLSESEIIEALDCIMEGKATPAQIGSFITALRIKGETIEEITGCAKVMRAKADKICPNVDYYIDTCGTGGDGTNTFNISTATAFVAAAGGVYVAKHGNRSVSSKSGSADVLEALGVNIDLDPVQVKECIEKVGIGFIYAPVFHKSMKHAAGPRKELGIRTIFNILGPLTNPSNAKGQVLGVFNPNLTELMANVLLNLGIERAMVIHGMDGMDEITTTTSTKVSEVRNNEVITYELFPENYGIALASPEDLTGGNAEENAQIIRRIFNGEKGPKRDIVVLNSAAALYVGKVVSSIEEGIGLAEEVIDSGKALQKLDEFVEFTNSFISYNEMSG
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: AIM19_SCHPO
Sequence: MENKELRKSYFQRIYQSYIPAYAFGGALIASVPRAFKRPYGGPFVPGCLLCGGFNAIGGLAIASGDLTNGSGICTAWSIAYLMINATKSIKSFRLYPIALTTFATANAVGYGKTFMNEY
What are the official names of this protein?
Altered inheritance of mitochondria protein 19 homolog.
What is the protein family that this protein belongs to?
Belongs to the AIM19 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: RR12A_POPTR
Sequence: MPTIKQLIRNTRQPIRNVTKSPALGGCPQRRGTCTRVYTITPKKPNSALRKVARVRLTSGFEITAYIPGIGHNSQEHSVVLVRGGRVKDLPGVRYHIVRGTLDAVGVKDRQQGRSQYGVKKPK
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits (By similarity).
What are the official names of this protein?
30S ribosomal protein S12-A, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL19_MYCTO
Sequence: MNRLDFVDKPSLRDDIPAFNPGDTINVHVKVIEGAKERLQVFKGVVIRRQGGGIRETFTVRKESYGVGVERTFPVHSPNIDHIEVVTRGDVRRAKLYYLRELRGKKAKIKEKR
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: FLAK_METVO
Sequence: MIAYAIGLLGLLIASIQDIKSREIENYIWIGMAVIGLLLSTYLSFTTGNFMPIISSISGFIICFIIGYLMFVLGIGGADGKILMGMGALIPSYAFPVYSSLQPLYTMEYIPWFPLLVFFNGVILMIVLPIYLFFKNLSNGVKPKKLKEYVLMLVGEYITVAEAKKGNKVVLGKGKDVKLIPSVNDDKNYDLSKYKDTQYVWATPELPLLVPIALSYIITPFLGDKILSIILPM
What is the function of this protein?
Cleaves the N-terminal leader peptide from preflagellins.  The processing of preflagellins is necessary for assembly of flagellins into a flagellum structure.
What are the official names of this protein?
Preflagellin peptidase, PFP.
What is the protein family that this protein belongs to?
Belongs to the peptidase A24 family. Archaeal preflagellin peptidase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DHQS_METJA
Sequence: MKFGWVNVIGDNWEEKKKIVTTALESSIPVVVAEPEDIEKIKELGNIKVASHSLDADIVLVNKNDNIEFLKEAKNLGKETAIYIPIESKEDEEFASEVARFGFVDNIILEGRDWTIIPLENLIADLFHRDVKIVASVNSVDEAKVAYEILEKGTDGVLLNPKNLEDIKELSKLIEEMNKEKVALDVATVTKVEPIGSGDRVCIDTCSLMKIGEGMLIGSYSRALFLVHSETVENPYVATRPFRVNAGPVHAYILCPGNKTKYLSELKAGDKVLIVDKDGNTREAIVGRVKIERRPLVLIEAEYKGDIIRTILQNAETIRLVNEKGEPISVVDLKPGDKVLIKPEEYARHFGMAIKETIIEK
What is the function of this protein?
Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3-dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis.
What are the official names of this protein?
3-dehydroquinate synthase, DHQ synthase, 3-dehydroquinate synthase II.
What is the protein family that this protein belongs to?
Belongs to the archaeal-type DHQ synthase family.
Protein: MURG_ANAMM
Sequence: MKKVVLAAGGTGGHIVPAALLCQVLADRGYRCVLYTDQYFLQYTARFPGIKGYVLLPLCKRSGGAVRLLKFCALLAYSCVLSYIKLRSLKPDLVIGFGAYASFPVLLSAWLMSVDAVLHEQNSVMGRVNRVFAGYARVIACGLPLRTVGNKLAHKVAHVGVPTDVKKAVKRPLAGDSINLVILGGSQGLCTFGKTFALAIAELPTNIRGRVFVTQQCGKGQLEVITELYARHGIKHKLSGFFTDMQNIIGEADLIISRAGATTIAEVMAAGRPAIYVPYERSSCSHQLYNAQLIESLGAGLCIEERTLDVSSARDALTNLLGDRNKLQEMSCNAAKHAMPDADAQFCAIVDGLLKG
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HIS3_SINFN
Sequence: MTLTFPAPSKDKAELETGPAFTPRFDEKGLVTAVVTDARDGELLMVAHMNAEALALTIETGIAHYYSRSRNSLWKKGESSGNTQAVQEIRTDCDQDAIWLKVTVAGHDATCHTGRRSCFYRTVGVENGKARVTITDEHRHFDPAQIYAEKKG
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2A4_ORYSI
Sequence: MEVGAKVPKKAGAGGRRGGGGPKKKPVSRSVKAGLQFPVGRIGRYLKQGRYSQRIGTGAPVYLAAVLEYLAAEVLELAGNAARDNKKNRIIPRHVLLAIRNDEELGKLLAGVTIAHGGVLPNINPVLLPKKTGSAAAKEAKEGKTPKSPKKATTKSPKKAAAA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Probable histone H2A.4.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RS7_DEIDV
Sequence: MARRRQAEVRPLQPDLVYQDVLVSAMINRIMEDGKKNLASRIFYGACRLVQERTGQEPLKVFKQAYDNIKPRVEVRSRRVGGSTYQVPVEVSARRQQSLTLRWMMSAVDGRPERTAIERLAGEIMDAAQGRGGAIKKKDDVERMAEANRAYAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: HEM3_PSEFS
Sequence: MSSREIRIATRKSALALWQAEYVKARLEQAHPGLKVSLVPMVSRGDKLLDSPLSKIGGKGLFVKELETALLENEADIAVHSMKDVPMDFPEGLGLFCICEREDPRDAFVSNTYASLDALPLGSIVGTSSLRRQAQLLTRRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFEDRITSAISVEDSLPAGGQGAVGIECRTADSDIHALLKPLDHHDTEVRVTAERALNKHLNGGCQVPIACYAVLEGENLWLRGLVGDPEGGNLLTAEVRGPQCDATALGIQVAQALLDKGAGAILQKVYGEAGPQ
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: PDXS_STRCO
Sequence: MSSTLSENQAPETGTARVKRGMAEQLKGGVIMDVVTPEQAKIAEDAGAVAVMALERVPADIRKDGGVARMSDPDMIEGIIGAVSIPVMAKSRIGHFVEAQVLQSLGVDYIDESEVLTPADEVNHSDKFAFTTPFVCGATNLGEALRRIAEGAAMIRSKGEAGTGNVVEAVRHLRQIKNEIARLRGYDNNELYAAAKELRAPYELVKEVSELGRLPVVLFSAGGVATPADAALMRQLGAEGVFVGSGIFKSGDPAKRAAAIVKATTFYDDPKIIADASRNLGEAMVGINCDTLPETERYANRGW
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: MURE_STRS2
Sequence: MITIERVLEILKADANFRHIKQNDQTDSTWTDVQFDALSYDSRTVSPMTLFFAKGLAFKKEFLEKAIEAGLAFYVSEINYEVGIPAIIVHDIKQAMSLIAMEFHGHPQKQLKLLAFTGTKGKTTAAYFAFNILKQSKKPAMLSTMNTTLDGKTFFKSTLTTPESLDLFAMMAEAVKNGMTHLIMEVSSQAYLVKRVYGLTFDVGVFLNISPDHIGPIEHPTFEDYFYHKRLLMDNSRAVIVNAGMDHFEVVKEQVSSKDHDFYGPTSENQISQSAGFDFTATGKLAGHYDIQLIGGFNQENAIAAGLACLRLGASLEDIHTGIAQTNVPGRMEVLTQQNGAKVFVDYAHNGDSVKKLIDVVLEHQTGKVFLILGAPGNKGESRRKDFGLLLNDYPQIEVILTADDPNREDPAAIAEQIRAHMTRTSNFILDREEAIRTAMSQTSSPKDAVIIAGKGADAYQIVNGEKAAYDGDLEVAKQYL
What is the function of this protein?
Catalyzes the addition of L-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase, L-lysine-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:L-Lys ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AC4_CLVN
Sequence: MPFGDNYIMSPINRRRCSRVSPVECLQLTWSKCELLVLEFKPRMSFSHTQIVLYPKNTCCHSFKHYLSHQTLSSLKSVESCIRMGNLTCMPSSNSRERSRLRTIVSSIVYTQAVAPISTPTFKVPNQAQMSSPIWIRTETPSNGDNFRSMDDLLEAVNNQRMMLTPKRLTAAVSQKLLM
What is the function of this protein?
Pathogenicity determinant (By similarity).  May act as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs.
What are the official names of this protein?
Protein AC4, Protein AL4.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae protein AC4/C4 family.
Protein: IDH_MYCTU
Sequence: MSNAPKIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAYAIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVPGWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGMYNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAAGLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESVVIATVESGKMTKDLAILIGPEQDWLNSEEFLDAIADNLEKELAN
What are the official names of this protein?
Isocitrate dehydrogenase [NADP], IDH, IDP, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
Protein: ARLY_BACFN
Sequence: MAQKLWEKSVEVNKDIERFTVGRDREMDLYLAKHDVLGSMAHITMLESIGLLTKEELAQLLTELKDIYASAERGEFVIEEGVEDVHSQVELMLTRRLGDVGKKIHSGRSRNDQVLLDLKLFTRTQIREVAEAVEQLFHVLIRQSERYKNVLMPGYTHLQIAMPSSFGLWFGAYAESLVDDMLFLQAAFKMCNKNPLGSAAGYGSSFPLNRTMTTELLGFDSLNYNVVYAQMGRGKMERNVAFALATLAGTISKLAFDACIFNSQNFGFVKLPDECTTGSSIMPHKKNPDVFELTRAKCNKLQSLPQQIMMIANNLPSGYFRDLQIIKEVFLPAFQELKDCLQMTTYIMNEIKVNEHILDDDKYLFIFSVEEVNRLAREGMPFRDAYKKVGLDIEAGHFSHDKQVHHTHEGSIGNLCNDEISALMQRTIEGFNFQGMEQAEKTLLGRK
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPXT3_GLOVI
Sequence: MTTAPSEDLLTLARWMAGDFSNQKQALAQPQTFAHIRVFFRPLPFAFFGTVGFYSEQTYDYDLWSPYRQGLHRLLDREGGIYIENYGLQDAGLYAGAGHDPEILATIPTDCLQPRRGCAMVFRREGDCFRGSVEPGNHCLIPRDGYWTYLVSEVELTESTWVSLDRGMDRETHRQIWGSQAGPLHFEKREGFDPPLPPLGKGG
What is the function of this protein?
Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins.
What are the official names of this protein?
Chromophore lyase CpcT/CpeT 3.
What is the protein family that this protein belongs to?
Belongs to the CpcT/CpeT biliprotein lyase family.
Protein: US26_HCMVM
Sequence: MRQSYRYASGAVVRRTLKGLRKLILCQDLRQDIRHLVRSYADMNISLPVSAPPGWRLDFVEFEDIFGSAAVTDGPETPWGQLICCEESLESLGVLQFSTTVLPRVHGPRSSSEDEDSDDDDFFVYVEEIEPPSQARLVLLLGRYETVWCLDRDCGVLYYLAHSLDDFARHGLLHCEAIYGEQMRTPLLTTQPDHIICDLRLHDNSISELQRVTCRYRGECVPLRTPGEMTRPLLLCGQAENLKGVWPFICMETEQFNDLLKFFVDRLCCETMIMGVVGESLPSGVFHADFVILVDRACEFFYFDVSRREIWRLADSVDMLLTVGLLKIYQAGRRFHYAVDDAERLEVPGRCPHENFPFWDRFGTVERVRASTRHHELRYKWLIRKDRFIVRPDWCSMRNSLDEVSGTADVSWDPRIRPDYPQTSDLECAKQYWQELNDHVREQTARYGPVRRYSVWCGMSSRLERAVKRLQQRIPRQNLMNPSLMNQGLCVYYSDEEEDQEEDDTSDDDDQEKETENPQNNIGSLTRTPSSPGSLEGVEERMLNVMKEAVAEQDRKKTQKKHKIDTAQRRVLTRRAARAAVLEGRPTPKPTMPHPVSYLPFWM
What are the official names of this protein?
Protein US26.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae US22 family.
Protein: LSPA_ECOLU
Sequence: MSQSICSTGLRWLWLVVVVLIIDLGSKYLILQNFALGDTVPLFPSLNLHYARNYGAAFSFLADSGGWQRWFFAGIAIGISVILAVMMYRSKATQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYVGDWHFATFNLADTAICVGAALIVLEGFLPSKAKKQ
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PGK_ERWT9
Sequence: MSVIKMTDLDLAGKRVLIRADLNVPVKEGKVTSDARIRASLPTIEAALKQGAKVMVTSHLGRPTEGEYNEEFSLLPVVNYLKEKLGAENVSLAKDYLDGVELAAGKLVVLENVRFNKGEKKDDETLSKKYAALCDIFVMDAFGTAHRAQASTHGVGKFAPVACAGPLLSAELEALGKALKSPARPMVAVVGGSKVSTKFDVLNSLVKIADTVIVGGGIANTFVAIENNVGKSLYEPDFVDAAKKLRDEYGIPVPVDSRVGTEFSETAPSTVKKVSEVQDNEEIMDFGDETALAMANLLKDAKTILWNGPVGVFEFPNFRKGTEIVANAIADSDAFSIAGGGDTLAAIDLFGIEDKISYISTGGGAFLEFVEGKVLPAVAMLEERAKQ
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CA2B_CONER
Sequence: MGMRMMFIVFLLVVLATTVVSFTLDHVLGLASEGRNAKAIDNALDQRDPKRQTPGCCWHPACGKNRCGRR
What is the function of this protein?
Alpha-conotoxins bind to the nicotinic acetylcholine receptors (nAChR) and inhibit them.  This peptide potently blocks muscular nicotinic acetylcholine receptor (CHRNA1-CHRNB1-CHRNG-CHRND), and has no effect on neuronal receptors.  It is able to totally displace [125I]-Bgtx from the Torpedo receptor with an inhibition constant (Ki) of 2. 2 and 0. 7 nM.
What are the official names of this protein?
Alpha-conotoxin EIIB, E1.2.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DXR_SHEPW
Sequence: MQSLVILGATGSIGASTLNVVKCNHEQYRVFALVANTNVAKMLEICIEHRPLVAHMVNAQAATELKRLLPSELAIEVTTGEDELLSLVSCAEVDTVMAAIVGAAGLPSTLAAVKAGKRVLLANKESLVMSGQLFIEAMQSSGATVLPVDSEHNAIFQCLSERTQLEIGRCDLAGAGISHILLTGSGGPFLNSELSTLSSMTPAQACKHPNWSMGQKISVDSASMMNKGLEYIEARWLFNASAEQLKVVIHPQSVIHSMVQYRDGSVIAQLGNPDMRTPIAHCMSFPQRISSGVEPLDFFKVGQLSFLEPDFNRFPCLALAIEACKQGQEATTVLNAANEISVQAFLEGQIRFTDIAIINEQSFKHVTAQSLTTIDDIMALDSQARQYALEAVNKLK
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: 3CAR1_PICAB
Sequence: MSVISILPLASKSCLYKSLMSSTHELKALCRPIATLGMCRRGKSVMASKSTSLTTAVSDDGVQRRIGDHHSNLWDDNFIQSLSSPYGASSYGERAERLIGEVKEIFNSLSRTDGELVSHVDDLLQHLSMVDNVERLGIDRHFQTEIKVSLDYVYSYWSEKGIGSGRDIVCTDLNTTALGFRILRLHGYTVFPDVFEHFKDQMGRIACSDNHTERQISSILNLFRASLIAFPGEKVMEEAEIFSATYLKEALQTIPVSSLSQEIQYVLQYRWHSNLPRLEARTYIDILQENTKNQMLDVNTKKVLELAKLEFNIFHSLQQNELKSVSRWWKESGFPDLNFIRHRHVEFYTLVSGIDMEPKHCTFRLSFVKMCHLITVLDDMYDTFGTIDELRLFTAAVKRWDPSTTECLPEYMKGVYTVLYETVNEMAQEAQKSQGRDTLSYVRQALEAYIGAYHKEAEWISSGYLPTFDEYFENGKVSSGHRIATLQPTFMLDIPFPHHVLQEIDFPSKFNDFACSILRLRGDTRCYQADRARGEEASCISCYMKDNPGSTQEDALNHINNMIEETIKKLNWELLKPDNNVPISSKKHAFDINRGLHHFYNYRDGYTVASNETKNLVIKTVLEPVPM
What is the function of this protein?
Terpene synthase (TPS) involved in defensive oleoresin formation in conifers in response to insect attack or other injury.
What are the official names of this protein?
Carene synthase, chloroplastic, PaJF67, PaTPS-3car, (+)-car-3-ene synthase, 3-carene cyclase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsd subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: BSG2_DROME
Sequence: MEVSADPYEQKLYQMFRSCETQCGLLDEKSLLKLCSLLELRDQGSALIASLGGSHQLGVSFGQFKEALLNFLGSEFDERSLVITDEPLNNTYIESPPESSDREVSPKLVVGTKKYGRRSRPQQGIYELSVTDSDNTDEDQLQQQQNQRSLNGCDELGVQVQRSSSQSDLPGSRRLRSVHTSGSKLKRCASLPARRKMNSNTTGATTSPTAAAKLKQLSIQSQAQHSSSVESLDTVTPQQLETISVHSIMEAWELASIPNTRNLLHVLGFDEEEEVNLQQLTKALEEELRGIDGDHEQSNMLRALAALQATELGNYRLAYRQQHEENLKLRADNKAANQRVALLAVEVDERHASLEDNSKKQVQQLEQRHASMVREITLRMTNDRDHWTSMTGKLEAQLKSLEQEEIRLRTELELVRTENTELESEQQKAHIQITELLEQNIKLNQELAQTSSSIGGTPEHSPLRPRRHSEDKEEEMLQLMEKLAALQMENAQLRDKTDELTIEIESLNVELIRSKTKAKKQEKQEKQEDQESAATATKRRGDSPSKTHLTEESPRLGKQRKCTEGEQSDASNSGDWLALNSELQRSQSQDEELTSLRQRVAELEEELKAAKEGRSLTPESRSKELETSLEQMQRAYEDCEDYWQTKLSEERQLFEKERQIYEDEQHESDKKFTELMEKVREYEEQFSKDGRLSPIDERDMLEQQYSELEAEAAQLRSSSIQMLEEKAQEISSLQSEIEDLRQRLGESVEILTGACELTSESVAQLSAEAGKSPASSPISYLWLQSTIQEPAKSLADSKDEATASAIELLGGSPSHKTASR
What are the official names of this protein?
Blastoderm-specific protein 25D.
Protein: PA2B2_PROFL
Sequence: MRTLWIMAVLLVGVDGSLVQLWKMIFQETGKEAAKNYGLYGCNCGVGRRGKPKDATDSCCYVHKCCYKKVTGCNPKMDSYSYSWKNKAIVCGEKNPPCLKQVCECDKAVAICLRENLGTYNKKYTIYPKPFCKKADTC
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that shows anticoagulant activities, strong myolytic activity, infiltration of polymorphonuclear cells, and edema in stromal tissues.  Induces cell death of Jurkat cells in a concentration-dependent manner.  Shows a low phospholipase A2 activity.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Basic phospholipase A2 BP-II, svPLA2, Basic protein II, BP2, BPII, PflLys49-PLA2 BPII, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. K49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TMED1_PONAB
Sequence: MMAAGAALALALWLLMPPVGVGGAGPPPIQDGEFTFLLPAGRKQCFYQSAPANASLETEYQVIGGAGLDVDFTLESPQGVLLVSESRKADGVHTVEPTEAGDYKLCFDNSFSTISEKLVFFELIFDSLQDDEEVEGWAEAVEPEEMLDVKMEDIKESIETMRTRLERSIQMLTLLRAFEARDRNLQEGNLERVNFWSAVNVAVLLLVAVLQVCTLKRFFQDKRPVPT
What is the function of this protein?
Potential role in vesicular protein trafficking, mainly in the early secretory pathway.  May act as a cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and may be involved in vesicle coat formation at the cytoplasmic side.  Plays a positive role in IL-33-mediated IL-8 and IL-6 production by interacting with interleukin-33 receptor IL1RL1.  Plays also a role in the modulation of innate immune signaling through the cGAS-STING pathway by interacting with RNF26.
What are the official names of this protein?
Transmembrane emp24 domain-containing protein 1, p24 family protein gamma-1, p24gamma1.
What is the protein family that this protein belongs to?
Belongs to the EMP24/GP25L family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus, cis-Golgi network membrane; Single-pass type I membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein.
Protein: TRHO_PROMM
Sequence: MNLQDDQTSADLFQVATFYSFTAWTEVTIACLLHDLLSLGDEHQLMGTVLLAEEGVNGTICGSVDGVSALLERLESDLIEGLFELKISWTPEQAFRRFKVRRKAEIVTMGLAGLNPSKTVGTYVDAHEWNDLIDDPDTLLIDTRNDYEVAIGEFKGAINPQTKCFRDFPAWVEQQLRSMVKAQTPARIAMYCTGGIRCEKATSYLIEKGFTNVHHLRGGILRYFEEVSQTESRWQGECFVFDQRVALNHQLSPGVHCLCHACGMPLTPEDQTMNSYLPGVQCRHCVDQFSDTDRIRFAERQRQMEHSSRK
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.