PharMolix/UniProtQA huggingface dataset:
Protein: DRE2_YEAST
Sequence: MSQYKTGLLLIHPAVTTTPELVENTKAQAASKKVKFVDQFLINKLNDGSITLENAKYETVHYLTPEAQTDIKFPKKLISVLADSLKPNGSLIGLSDIYKVDALINGFEIINEPDYCWIKMDSSKLNQTVSIPLKKKKTNNTKLQSGSKLPTFKKASSSTSNLPSFKKADHSRQPIVKETDSFKPPSFKMTTEPKVYRVVDDLIEDSDDDDFSSDSSKAQYFDQVDTSDDSIEEEELIDEDGSGKSMITMITCGKSKTKKKKACKDCTCGMKEQEENEINDIRSQQDKVVKFTEDELTEIDFTIDGKKVGGCGSCSLGDAFRCSGCPYLGLPAFKPGQPINLDSISDDL
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins (PubMed:18625724, PubMed:19194512, PubMed:20802492, PubMed:21902732, PubMed:31040179).  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35.  Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18 (PubMed:20802492).  TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit RNR2 (PubMed:21931161, PubMed:24733891).  Has anti-apoptotic effects in the cell.  Involved in negative control of H(2)O(2)-induced cell death (PubMed:19194512).
What are the official names of this protein?
Fe-S cluster assembly protein DRE2, Anamorsin homolog.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space.
Protein: EFTU_LEPBP
Sequence: MAKEKFDRSKPHLNIGTIGHVDHGKTTLTAAITTTLAKLVGGKNKAIAYDQIDNAPEEKARGITIATSHQEYETPNRHYAHVDCPGHADYVKNMITGAAQMDAAILVVSATDGAMPQTKEHILLARQVGVPYIVVYLNKADMLAADERDDMVEMVKEEIKDLLNKYNFPGDKTPFISGSALKALEGEDSDLGMKSILKLMEAVDTYVPNPTRIVDKPFLMPVEDVFSITGRGTVATGRVEQGVLKINDEIEIVGIRDTTKSVVTGIEMFRKLLDQAEAGDNIGALLRGTKKEDIERGQVLAKPGTITPHRKFKAEVYVLTKDEGGRHTPFFNNYRPQFYFRTTDITGVCNLPGGMEMVMPGDNVTMSIELIHPIAMDQGLKFAIREGGRTIGSGVVAEIVE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOB_ECO45
Sequence: MKRAFIMVLDSFGIGATEDAERFGDVGADTLGHIAEACAKGEADNGRKGPLNLPNLTRLGLAKAHEGSTGFIPAGMDGNAEVIGAYAWAHEMSSGKDTPSGHWEIAGVPVLFEWGYFSDHENSFPQELLDKLVERANLPGYLGNCHSSGTVILDQLGEEHMKTGKPIFYTSADSVFQIACHEETFGLDKLYELCEIAREELTNGGYNIGRVIARPFIGDKAGNFQRTGNRHDLAVEPPAPTVLQKLVDEKHGQVVSVGKIADIYANCGITKKVKATGLDALFDATIKEMKEAGDNTIVFTNFVDFDSSWGHRRDVAGYAAGLELFDRRLPELMSLLRDDDILILTADHGCDPTWTGTDHTREHIPVLVYGPKVKPGSLGHRETFADIGQTLAKYFGTSDMEYGKAMF
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIF3A_DROMO
Sequence: MARYTQRPENALKRANEFIEVGKPLRALDTLQEVFRNKRWNYAYSETVIEPLMFKYLYLCVELKKSHIAKEGLFQYRNMFQLVNVNSLENVIRGYLKMAEEHTEAAQAQSSAAVAVLELDDLDNIATPESILMSAVCGEDAQDRSDRTILLPWVKFLWESYCQCLELLRVNTHCEALYHDIARMAFQFCLKYNRKSEFRRLCDKLRKHLEDICKSSNQTTGVSINKVETQQLCLDTRLYLLDSAIQMELWQEAYKAIEDIHGLMAMSKKTPVPKTMANYYQKLAMVFSKAGNQLFHAAALLKLFQLTRELKKNLTKDDLQRMAAHVLLATLSIPLPSAHPEFDRFIEADKSPLEKAQKLAVLLGLPQPPTRVSLIREVVRLNVPNLVSEDFRNLYNWLEVDFNPLNLCKRIQSIVDTIEASETENTLLTPYIQSLKDVTIMRLIRQISQVYESIEFKRLLELAPFCNIFELEKLLVESVRHNDMQIRIDHQRNSIYFGTDLTESQREYRPDGPTLQSMPSEQIRSQLVNMSTVLTRAVSIVYPNRERDQRAKLRSQMVQHYHEIKDREHQRILQRQKIIEDRKEFIEKQNNAREEEEARRHEEESRKAKLAEQKRLEQEQEERERKRHENEIQAIKEKSLKEKVQQISQTAHGKKMLSKLDEEGIKKLDAEQIAMRESEELQRERKELQSKLKSQEKKIDYFERAKRLEEIPLFEKYLAEKNVKDKEFWEATEATRIENAIAERKDAVSQQERLKRMYPDRDEFLEALKKERASLFVEKLKKFEIALAEERKKRLAERVVRRREERRQAYLRAKEEERFRKEEEIRLAREAEERAAAEARRLEREAEDEKRRQQYEKQRAKEEEAERKIQEDRERLAREVAVERERSEKERDVWRPRGDRSERPSAAPAGGASEWRRNAPTSDRNDRNDRNERNDRSDRNDRNDRSERIERSDRNDRPERKDTDGGADSSWRVRREPVEPQRERGGGAGGGPSGRDDKWRRGGDRSERLGGDRDRDRDRDSFRRNDGPRRDDDRGGFRRDDQPQRDTGSNWRDSPRQNDRDNRDNRRPAGDRRDIRGAGPKEGGGGGGGGNWRTAPSPRDEKPPVKRDQPQDKENKAGDDGEWTSVKRR
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit A, eIF3a, Eukaryotic translation initiation factor 3 subunit 10.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_BACC4
Sequence: MHYPEPISKLIDSFMKLPGIGPKTAVRLAFFVLDMKEDDVLGFAKALVNAKRDLAYCSVCGHITDRDPCYICNDSHRDQSVVCVVQEPKDVIAMEKMKEYQGVYHVLRGAISPMEGIGPEDINIPQLLKRLHDETVQEVILATNPNIEGEATAMYISRLLKPTGIKVTRIAHGLPVGGDLEYADEVTLSKALEGRREV
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: PEPT_STRT2
Sequence: MAYDLLLERFLRYAKINTRSDENATRTPTTQSQVDFALNILKPELEELGLSNIHYLESNGYLVATLPANDDRLTRKIGFISHMDTADFNAEGVSPQVIESYDGGIIPLGTSGYNLDPADFPNLQNYIGQTLITTDGTTLLGADDKSGIAEIMTALAHLKANPEIKHCEIRVGFGPDEEIGIGADKFDVDDFDVDFAYTVDGGPLGELQYETFSAAAAELIFHGRNVHPGTAKGQMVNALQLAIDFHNQLPAEDRPELTDGYQGFNHLQTMTGTVEEANSSYIIRDFETESFENRKATFQEIADKMNQAYGQTRVDLVIKDQYYNMRQVIEKDMMPVELAKEVMEDLGIVPVIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRYEFVSLQTMEKAVDVILGIVSKP
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_STRPS
Sequence: MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITNRQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKVMFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: MLPI_BORBU
Sequence: MKIINILFCLFLLMLNSCNSNDTNTSQTKSRQKRDLTQKEATQEKPKSKEDLLREKLSEDQKTHLDWLKTALTGAGEFDKFLGYDEDKIKGALNHIKSELDKCTGDNSEQQKSTFKEVVKGALGGGIDSFATSASSTCQAQQ
What is the function of this protein?
An outer membrane protein that may participate in pathogenesis.  Some human Lyme disease patients have antibodies against this protein (PubMed:10948116).  The Mlp proteins probably undergo intragenic recombination, generating new alleles (Probable).
What are the official names of this protein?
Lipoprotein MlpI.
What is the protein family that this protein belongs to?
Belongs to the Multicopy lipoprotein (Mlp) family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: CP2F3_CAPHI
Sequence: MDSISTAILLLILALICLLLTTSSKGKGRLPPGPRALPFLGNLLQLRSQDMLTSLTKLSKEFGAVYTVYLGPRRVVVLSGYQAVKEALVDQAEEFSGRGDYPAFFNFTKGNGIAFSNGDRWKALRKYSLQILRNFGMGKRTIEERILEEGHFLLEELRKTQGKPFDPTFVVSRSVSNIICSVIFGSRFDYDDDRLLTIIHLINENFQIMSSPWGEMYNIFPNLLDWVPGPHRRLFKNYGRMKNLIARSVREHQASLDPNSPRDFIDCFLTKMAQEKQDPLSHFFMDTLLMTTHNLLFGGTETVGTTLRHAFRLLMKYPEVQVRVQEEIDRVVGRERLPTVEDRAEMPYTDAVIHEVQRFADIIPMSLPHRVTRDTNFRGFTIPRGTDVITLLNTVHYDPSQFLKPKEFNPEHFLDANMSFKKSPAFMPFSAGRRLCLGEALARMELFLYLTAILQSFSLQPLGAPEDIDLTPLSSGLGNVPRPYQLCVRAR
What is the function of this protein?
Bioactivates 3-methylindole (3MI) by dehydrogenation to the putative electrophile 3-methylene-indolenine.  Stereoselectively catalyzes the formation of the 1R,2S-oxide from naphthalene.  Lack activity with other common P450 substrates including 7-ethoxycoumarin.
What are the official names of this protein?
Cytochrome P450 2F3, CYPIIF3.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: RS7_HAEIN
Sequence: MPRRRSVEARKILPDPKFGSELLAKFINVIMVDGKKSVAESIVYGALETLAQRTGKEPLEAFEVALENVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALGMRWIVEAARKRGDKSMALRLANELSDASDNKGAAVKKREDVHRMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: GPDA_STRPQ
Sequence: MTKQKVAILGPGSWGTALSQVLNDNGHDVRLWGNIPDQIEEINTKHTNRHYFKDIVLDKNITATLDLGQALSDVDAVLFVVPTKVTRLVARQVAAILDHKVVVMHASKGLEPETHERLSTILEEEIPAHFRSEVVVVSGPSHAEETIVRDITLITAASKDIEAAKYVQSLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVITRGLAEITRLGVKLGADPLTYSGLSGVGDLIVTGTSVHSRNWRAGAALGRGEKLEDIERNMGMVIEGIATTKVAYEIAQDLGVYMPITTAIYKSIYEGADIKESILGMMSNEFRSENEWH
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAA_SHEB5
Sequence: MSDIHEHKILILDFGSQYTQLIARRIREIGVYCELWAWDVTEAQIREFAPNGIILAGGPESVTAENSPRAPEYVFTAGVPVLGICYGMQTMSEQLGGKVIQGVGEGEFGYAQIEMLTDSLLFKGIEDAVNSEGKPLLDVWMSHGDKVSAIPEGFVAVAKTDTCPFAAMANEEKQFFGVQFHPEVTHTRQGMRMLSHFALDICGCAANWKPSSIIEDAIERLKKQIGDDEVILGLSGGVDSSVVAMLLHRAIGKKLTCVFVDNGLLRLNEAEQVMEMFGDHFGLNIIHVDAENRFLDAMKGEADPEAKRKIIGRVFVEIFDEESKKCANAKWLAQGTIYPDVIESAGSATGKAHVIKSHHNVGGLPDDMELGLVEPLRELFKDEVRKIGLELGLPYNMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELHKADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETVDFMTAHWAHLPYDFLGRVSNRIINEVDGISRVVYDISGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: PTH_RUEPO
Sequence: MRLFVGLGNPGAKYARNRHNIGFMALDRIAEDHGFGPWRVKFQGQIAEGRLGREKVLLLKPETFMNRSGQSVGEAMRFYKLDSTDITVLHDELDLAPGKVKVKAGGGHAGHNGLRSIHDHIGAAYDRVRLGIGHPGRKEAVAGYVLHDFARADEDWLEDVLRGVSEGAPHLAAGDGARFMNSVALRTAPPRPSTGTGRPPAKTPARAEEPPAPAASPAPATAPLPDARSPLQKLVDRFK
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_GEOUR
Sequence: MMLGKKLHVKKNDTVIVITGKDKAKTGKVLQILPKKDGVLVEGINIVKRHTRPRGSEAGAIVEKEAVIHVSNVMIYCNKCGKPVRTRINTLEDGKKVRICVKCGEAFDK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: RS15_PROM1
Sequence: MSLGTEEKQNLINTHQVHPTDTGSVEVQVAMLTTRISKLSTHLQGNIHDFSSRQGLLKMIGQRKRLLGYVRSKSEKRYTELIEKLAIRG
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: ACKA_METTE
Sequence: MKVLVINAGSSSLKYQLIDMTNESALAVGLCERIGIDNSIITQKKFDGKKLEKLTDLPTHKDALEEVVKALTDDEFGVIKDMGEINAVGHRVVHGGEKFTTSALYDEGVEKAIKDCFELAPLHNPPNMMGISACAEIMPGTPMVIVFDTAFHQTMPPYAYMYALPYDLYEKHGVRKYGFHGTSHKYVAERAALMLGKPAEETKIITCHLGNGSSITAVEGGKSVETSMGFTPLEGLAMGTRCGSIDPAIVPFLMEKEGLTTREIDTLMNKKSGVLGVSGLSNDFRDLDEAASKGNRKAELALEIFAYKVKKFIGEYSAVLNGADAVVFTAGIGENSASIRKRILTGLDGIGIKIDDEKNKIRGQEIDISTPDAKVRVFVIPTNEELAIARETKEIVETEVKLRSSIPV
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.  Can also phosphorylate propionate, but has very low activity toward butyrate.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SDHE_PECAS
Sequence: MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLNDSDKRAFVRLLQSDDPDLFNWLMNHGEPKDGELKRMISLIQTRNKDRGPVAM
What is the function of this protein?
An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins.  Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
What are the official names of this protein?
FAD assembly factor SdhE.
What is the protein family that this protein belongs to?
Belongs to the SdhE FAD assembly factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_RALSO
Sequence: MANTALADTRSELEAGARALGLPLEGVQLDRLLAYQVLLAKWNRVYNLTAIRDAGDMLTHHLLDSLAAVPRIAELVRRVQPEASRVLDVGSGGGLPGIPLAIACPDIGVTMVDIVQKKTAFLTQCRAELGLTNAQSHWGHVEKLADAVGYGVITSRAFAELNDFVRLAGHLLAPGGRMVAMKGVRPDAEIARLPEGWAVESIERLTVPGLPAERHLVILAPSA
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_DEHMB
Sequence: MSARGQDIVSIIKEQIKEFGAPVSMTSVGSVIEVGDGIARIHGLSNAKYNELLEFPGGVLGIALNLEEDSVAAVILGEDSNIKEGDEVKATGRISEITVGKGMIGRVVDPLGRPLDGKGPIKAESTRPLERIAPNVVDRKSVNTPVQTGIKAIDAMIPIGRGQRELIIGDRSTGKTAIALDTIINQKGGDLVCIYVAIGQKASKVARIVALLEQYGAMEHTIVVAANSSDAVALQYLAPYAGCAIGEEFMEQGKDALVVYDDLTKHAWAYRQLSLLLRRPPGREAYPGDLFYLHSRLLERAARLNDKLGGGSLTALPIIETQAGDVSAYVPTNVISITDGQIYLEPDMFNAGIRPAVNVGISVSRVGSSAQTKAMKKVAGKLKMDMGQYRELAAFAQFGTSELDKSTRMQLERGQRVTEVLKQGQYQPVPAAKQVAILYATLNGYLDNIEVGKVRDYESGLYRFLEANFASVLTAIAKENVISADTEKTLKTALDEYKKGLVV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: 3MGH_MYCSK
Sequence: MVSVELLRVDPLTAARRLLGAVLTCRGVSATVVEVEAYGGPPDGPWPDAAAHSYRGPGPRNQVMFGPAGRLYTYRSHGIHVCANVACADDGVAAAVLLRAAVIESGHDVVQRRRGEAVRESAFARGPGNLCSALGITMADNGIDVFAEDSPVHLRLGEEQPCIAGPRVGVSKAADRPWRLWLAGRPEVSAYRRSPRAPAPGGSD
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: AGRG1_MACMU
Sequence: MTAQSLLQTTLFLLSLLFLVQGAHGRGHREDFRFCSQRNQTHISSLHYKFTPDLRISIENSEEALTVHAPFPEAHPASRSFPHPRGLYHFCLYWDRHAGRLHLLYGKHDFLLSDQASSLLCFQHQEESLAQGPPLFATSVTSWWSPQNISLPSASNFTFSFHSPPHTAAHNASVDMCELKRDLQLLSQFLKHPQKASRRPSATPASQQLQSLESKLTSVRFMGDTVSFEEDRVNATVWKLQPTAGLQDLHIHSRQEQEQSEILEYSVLLPRTLFQRTKGRRGEAEKRLLLVDFSSQALFQDKNSSQVLGEKVLGIVVQNTKVANLTEPVVLTFQHQPQPKNVTLQCVFWVEDPTLSNPGRWSSAGCETVRRETQTSCFCNHLTYFAVLMVSSVEVDAVHKHYLSLLSYVGCVVSALACVVTIAAYLCSRRKPRDYTIKVHMNLLLAVFLLDVSFLLSEPVALTGSQSGCRASAIFLHFSLLACLSWMGLEGYNLYRLVVEVFGTYIPGYLLKLSAMGWGFPIFLVTLVALVDVDNYGPIILAVHRTPESVIYPSMCWIRDSLVSYITNLGLFSLVFLFNMAMLGTMVVQILRLRPHTQKWSHVLTLLGLSLVLGLPWALIFFSFASGTFQLVVLYLFSIITSFQGFLIFLWYWSMRLQARGGPSPLKSNSDSARLPISTGSTSSSRI
What is the function of this protein?
Receptor involved in cell adhesion and probably in cell-cell interactions.  Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells.  Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination.  Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12.  Plays a role in the maintenance of hematopoietic stem cells and/or leukemia stem cells in bone marrow niche (By similarity).  Plays an essential role in testis development (By similarity).  Plays a critical role in tumourigenesis.
What are the official names of this protein?
Adhesion G-protein coupled receptor G1, G-protein coupled receptor 56.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [ADGRG1 N-terminal fragment]: Secreted. Note=Interaction with its ligand COL3A1 leads to the release of ADGRG1 NT from the membrane and triggers the association of ADGRG1 CT with lipid rafts. SUBCELLULAR LOCATION: [ADGRG1 C-terminal fragment]: Membrane raft.
Protein: DB127_HUMAN
Sequence: MGLFMIIAILLFQKPTVTEQLKKCWNNYVQGHCRKICRVNEVPEALCENGRYCCLNIKELEACKKITKPPRPKPATLALTLQDYVTIIENFPSLKTQST
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Beta-defensin 127, Beta-defensin 27, DEFB-27, Defensin, beta 127.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: LEUNG_ARATH
Sequence: MSQTNWEADKMLDVYIHDYLVKRDLKATAQAFQAEGKVSSDPVAIDAPGGFLFEWWSVFWDIFIARTNEKHSEVAASYIETQMIKAREQQLQQSQHPQVSQQQQQQQQQQIQMQQLLLQRAQQQQQQQQQQHHHHQQQQQQQQQQQQQQQQQQQQHQNQPPSQQQQQQSTPQHQQQPTPQQQPQRRDGSHLANGSANGLVGNNSEPVMRQNPGSGSSLASKAYEERVKMPTQRESLDEAAMKRFGDNVGQLLDPSHASILKSAAASGQPAGQVLHSTSGGMSPQVQTRNQQLPGSAVDIKSEINPVLTPRTAVPEGSLIGIPGSNQGSNNLTLKGWPLTGFDQLRSGLLQQQKPFMQSQSFHQLNMLTPQHQQQLMLAQQNLNSQSVSEENRRLKMLLNNRSMTLGKDGLGSSVGDVLPNVGSSLQPGGSLLPRGDTDMLLKLKMALLQQQQQNQQQGGGNPPQPQPQPQPLNQLALTNPQPQSSNHSIHQQEKLGGGGSITMDGSISNSFRGNEQVLKNQSGRKRKQPVSSSGPANSSGTANTAGPSPSSAPSTPSTHTPGDVISMPNLPHSGGSSKSMMMFGTEGTGTLTSPSNQLADMDRFVEDGSLDDNVESFLSQEDGDQRDAVTRCMDVSKGFTFTEVNSVRASTTKVTCCHFSSDGKMLASAGHDKKAVLWYTDTMKPKTTLEEHTAMITDIRFSPSQLRLATSSFDKTVRVWDADNKGYSLRTFMGHSSMVTSLDFHPIKDDLICSCDNDNEIRYWSINNGSCTRVYKGGSTQIRFQPRVGKYLAASSANLVNVLDVETQAIRHSLQGHANPINSVCWDPSGDFLASVSEDMVKVWTLGTGSEGECVHELSCNGNKFQSCVFHPAYPSLLVIGCYQSLELWNMSENKTMTLPAHEGLITSLAVSTATGLVASASHDKLVKLWK
What is the function of this protein?
Transcription repressor subunit of the SEU-LUG transcriptional corepressor of the C class floral homeotic gene AGAMOUS during the early stages of floral meristem development.  Is part of the A class cadastral complex that define the boundaries between the A and C class homeotic genes expression and function.  Interacts together with APETALA2 and SEUSS to repress AGAMOUS expression.  Also plays a role in ovule and pollen development (PubMed:11782418, PubMed:15277686, PubMed:7743940).  Implicated in embryo and floral development (PubMed:18390806).  Involved in post-synthesis cell wall modifications necessary for mucilage extrusion from seeds upon imbibition, probably by promoting the expression of genes required for mucilage maturation (PubMed:21362134, PubMed:21402796).  Involved in vegetative leaf morphogenesis at later stages of leaf development by restricting cell expansion during leaf growth (PubMed:15208345).  Regulates the maintenance on leaf polarity and meristem activity as well as the initiation of embryonic shoot apical meristem (SAM) development (PubMed:19837869).
What are the official names of this protein?
Transcriptional corepressor LEUNIG, Protein ROTUNDA2.
What are the subcellular locations of this protein?
Nucleus.
Protein: YQGF_HAEDU
Sequence: MATTILAFDFGTYSIGCAVGQSITKTAQSLTAFKSQDGIPNWQHIEKIIKEWQPDLLVVGLPLNMDGSEQPLTQRARKFANRLNGRFNLPVALQDERLTTTEAKSEIFSRGGYKALKKDKIDTISACLILESWFDNNP
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYK_THET2
Sequence: MNDQTRQRLLNLEALVEAGFAPYPYRFPKTHSAEAILKAKRGAPPESEWPEEEVAVAGRLVALRRMGKVTFAHLLDETGRIQLYFQRDLTPKYELLKKLDVGDILGVRGHPFTTKTGEVTVKVLDWTPLVKSLHPLPDKWHGLRDKEVRYRQRYLDLIVNPEVREVFRRRSEIVRYIRRFFEAKGFLEVETPILQPTTGGAEARPFKTYHNALDHEFYLRISLELYLKRLLVGGYEKVFEIGRNFRNEGIDHNHNPEFTMLEAYWAYADYQDMAGLVEELLSGLVLHLFGSHEVPYQGRVLNFKPPFRRISFVEALKEKAGLPFDPLDLERLRLWADAHHPELSQVPNYKLLDKLFGIYVEPELQDPTFVFDFPLAISPLAKRHREKPGLVERWDLYAGGMELAPCYSELNDPLDQRERFLEQARRRKEGDEEAPEPDEDFLLALEYGMPPAAGLGLGIDRLAMLLTDQPSLRDVLLFPLLKPKKEAVEEGV
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CVC1_VZVD
Sequence: MEAHLANETKHALWHNDHTKGLLHVVIPNAGLIAAGIDPALLILKKPGQRFKVEVQTRYHATGQCEPWCQVFAAYIPDNALTNLLIPKTEPFVSHVFSATHNSGGLILSLPVYLSPGLFFDAFNVVAIRINTGNRKHRDICIMYAELIPNGTRYFADGQRVLLLCKQLIAYIRCTPRLASSIKIYAEHMVAAMGESHTSNGDNIGPVSSIIDLDRQLTSGGIDDSPAETRIQENNRDVLELIKRAVNIVNSRHPVRPSSSRVASGLLQSAKGHGAQTSNTDPINNGSFDGVLEPPGQGRFTGKKNNSSASIPPLQDVLLFTPASTEPQSLMEWFDICYAQLVSGDTPADFWKRRPLSIVPRHYAESPSPLIVVSYNGSSAWGGRITGSPILYHSAQAIIDAACINARVDNPQSLHVTARQELVARLPFLANVLNNQTPLPAFKPGAEMFLNQVFKQACVTSLTQGLITELQTNPTLQQLMEYDIADSSQTVIDEIVARTPDLIQTIVSVLTEMSMDAFYNSSLMYAVLAYLSSVYTRPQGGGYIPYLHASFPCWLGNRSIYLFDYYNSGGEILKLSKVPVPVALEKVGIGNSTQLRGKFIRSADIVDIGICSKYLPGQCYAYICLGFNQQLQSILVLPGGFAACFCITDTLQAALPASLIGPILDRFCFSIPNPHK
What is the function of this protein?
Capsid vertex-specific component that plays a role during viral DNA encapsidation, assuring correct genome cleavage and presumably stabilizing capsids that contain full-length viral genomes.
What are the official names of this protein?
Capsid vertex component 1.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae CVC1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.