PharMolix/UniProtQA huggingface dataset:
Protein: EMF2_ARATH
Sequence: MPGIPLVSRETSSCSRSTEQMCHEDSRLRISEEEEIAAEESLAAYCKPVELYNIIQRRAIRNPLFLQRCLHYKIEAKHKRRIQMTVFLSGAIDAGVQTQKLFPLYILLARLVSPKPVAEYSAVYRFSRACILTGGLGVDGVSQAQANFLLPDMNRLALEAKSGSLAILFISFAGAQNSQFGIDSGKIHSGNIGGHCLWSKIPLQSLYASWQKSPNMDLGQRVDTVSLVEMQPCFIKLKSMSEEKCVSIQVPSNPLTSSSPQQVQVTISAEEVGSTEKSPYSSFSYNDISSSSLLQIIRLRTGNVVFNYRYYNNKLQKTEVTEDFSCPFCLVKCASFKGLRYHLPSTHDLLNFEFWVTEEFQAVNVSLKTETMISKVNEDDVDPKQQTFFFSSKKFRRRRQKSQVRSSRQGPHLGLGCEVLDKTDDAHSVRSEKSRIPPGKHYERIGGAESGQRVPPGTSPADVQSCGDPDYVQSIAGSTMLQFAKTRKISIERSDLRNRSLLQKRQFFHSHRAQPMALEQVLSDRDSEDEVDDDVADFEDRRMLDDFVDVTKDEKQMMHMWNSFVRKQRVLADGHIPWACEAFSRLHGPIMVRTPHLIWCWRVFMVKLWNHGLLDARTMNNCNTFLEQLQI
What is the function of this protein?
Polycomb group (PcG) protein.  Involved in flowering processes by repressing unknown target genes and preventing reproductive development.  Participates in polycomb group (PcG) protein complex-mediated (probably in complex with EMF1) silencing of the flower homeotic genes AGAMOUS (AG), PISTILLATA (PI), and APETALA3 (AP3), as well as of some regulatory genes such as ABSCISIC ACID INSENSITIVE3 (ABI3), LONG VEGETATIVE PHASE1 (LOV1), and FLOWERING LOCUS C (FLC) during vegetative development, by mediating trimethylation of histone 3 lysine 27 on the AG chromatin (H3K27me3).  PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development.  PcG proteins are not required to initiate repression, but to maintain it during later stages of development.  They probably act via the methylation of histones, rendering chromatin heritably changed in its expressibility.
What are the official names of this protein?
Polycomb group protein EMBRYONIC FLOWER 2.
What is the protein family that this protein belongs to?
Belongs to the VEFS (VRN2-EMF2-FIS2-SU(Z)12) family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FMT_BORBU
Sequence: MKIFFVSSSSIALEVFKEIVKHYEVVGVLTLPDRPKGRGQKLSQNVIKSEAIARNIKVLDPLILDDNVLNLVRDLNPDLMLVFSYGKIFKKEFLDLFPKGCINVHPSLLPKYRGVSPIQSAILNGDCVSGVTIQSMALEMDSGNILVQKNFKIRSYDTSHDISKLVSSLSPSLVLEALEKISKGFLGIPQKSSEATFCSFLKKESGFIDFNLSAFEIKNKINACNPWPLVRVRLDYNDIIFHRADFLEVDLYKERKIGEIVDFNPEKGLFVNTGKGILLLLEVQRPGRKVLDFKSFYNGSRQLIGQVFSSIE
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: UGPC_RHOP5
Sequence: MASVTLRNVRKTYPGGFEAIKGIDFAVGDGQFCVLVGPSGCGKSTLLRMVAGLETITAGEIDIGGRVVNTIEPADRDIAMVFQNYALYPHMSVYNNMAYGLRNRGMKKPDIDARVREAARILEIEPLLQRKPKQLSGGQRQRVAMGRAIVRQPKVFLFDEPLSNLDAKLRIAMRVEIRKLQRRLATTAIYVTHDQLEAMTLADQLVVMNGGVVEQIGSPLEVYRKPATTFVASFIGAPPMNLMQLDGDALRGQLAGGAGAGVLGIRPEDLTLLTDGSAPEGGVAIELRIEAVERVGPESFVYGSRSNGGAAVSPHPGERPAGEIIVRVPGEIAPELGARVTVAAPRQKLHLFDAGGRRRID
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
sn-glycerol-3-phosphate import ATP-binding protein UgpC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. sn-glycerol-3-phosphate importer (TC 3.A.1.1.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: REX_CLOBH
Sequence: MDKKKNISMAVIRRLPKYHRYLYELLKNDVDRISSKELSEKIGFTASQIRQDLNCFGDFGQQGYGYNVSELHHQISNILGLNNPYNIIIIGAGNIGQALANYTRFSKLGFNVKAMFDTNPKLIGLKIREIEILDIDYLSSYLEKNNIDIGIICVPHDNAQKVANILVKNDIKGIWNFAPIDLSVPEDVVVENVHLSDSLLTLTCLINKTE
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRK1_SCHPO
Sequence: MDIEKSDKWTYVKERKVGEGTYAVVFLGRQKETNRRVAIKKIKVGQFKDGIDISALREIKFLRESRHDNVIELVDVFSTKSNLNIILEFLDSDLEMLIKDKFIVFQPAHIKSWMVMLLRGLHHIHSRFILHRDLKPNNLLISSDGVLKLADFGLSRDFGTPSHMSHQVITRWYRPPELFMGCRSYGTGVDMWSVGCIFAELMLRTPYLPGESDLDQLNVIFRALGTPEPEVIKSMQQLPNYVEMKHIPPPNGGMEALFSAAGHEEIDLLKMMLDYNPYRRPTAQQALEHHYFSALPKPTHPSLLPRKGGEEGIKHVSSDLQRQNNFPMRANIKFV
What is the function of this protein?
Protein kinase essential for cell proliferation, where it is required for completion of cytokinesis.  Phosphorylates the C-terminal repeat domain (CTD) of RNA polymerase II.
What are the official names of this protein?
Serine/threonine-protein kinase crk1, Mitotic catastrophe suppressor 6.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RNY_LISMO
Sequence: MTIAITIISSLLFLIVGLVVGSLIFKSSTEKKLAAARGTAELIVEDAKKEAETTKKEALLEAKEENHRLRTEIENELRGRRTETQKAENRLLQREENLDRKDTSLSKREATLERKEESISKRQQQIEEKESKLAEMIQAEQTELERISALSKEEAKSIILNQVEEELTHDTAIMVKESENRAKEESDKKAKNILSLAIQRCAADHVAETTVSVVTLPNDEMKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARIALEKLVQDGRIHPARIEEMVDKARKEVDEHIREVGEQATFEVGIHSIHPDLIKILGRLRYRTSYGQNVLNHSLEVSKLAGILAGELGEDVTLAKRAGLLHDIGKAIDHEIEGSHVEIGVELATKYKENDVVINSIASHHGDTEATSVIAVLVAAADALSAARPGARSETLENYIRRLEKLEEISESYDGVEKSYAIQAGREVRIIVEPDTIDDLSSYRLARDIRKRIEEELDYPGHIKVTVIRETRAVEYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: CCSA_DAUCA
Sequence: MIFSTLEHILTHISFSIVCIVITIHLITLLIDEIIKLNNSSEKGMIATFLCITVLLVTRCIYSGHLPLSDLYESLIFLSWSLSFIHIVPYFKKNKSHLSTITASSVIFTQGFATSGLLTEIHQSAILVPALQSEWLIMHVSMMILGYAALLCGSLLSVALLVLTFRKNRNLLCKKNPLLLKLTEEFSFGEIQYINEINNIFGNASFFSDNNYYRSQLIQQLDYWSYRVISLGFIFLTIGILSGAVWANEAWGSYWNWDPKETWAFITWIVFAVYLHTRTNTNLQVENSAIVASMGFLIIWICYFGVNLLGIGLHTYGSFTLTSN
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: UNG_ECOSM
Sequence: MANELTWHDVLAEEKQQPYFLNTLQTVASERQSGVTIYPPQKDVFNAFRFTELGDVKVVILGQDPYHGPGQAHGLAFSVRPGIATPPSLLNMYKELENTIPGFTRPNHGYLESWARQGVLLLNTVLTVRAGQAHSHASLGWETFTDKVISLINQHREGVVFLLWGSHAQKKGAIIDKQRHHVLKAPHPSPLSAHRGFFGCNHFVLANQWLEQRGETPIDWMPVLPAESE
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C298B_XENLA
Sequence: MVRLHIKRGDESQFLFDTSVIVPVEALVKQITAIYNGILKIDRICSEMAELAEHDLKLKDEWEERCVPSGGSVFKKDEIGRRNGHAPNDSMKKVLQKTMEEAKALISKKQAEANVCVTLEMVKEATDQLRGAVMIVYPMGLPPHDPIRMEFENNEDLSGTHAGQLVIQEPESQLWWAGKELQRKQKLSDYVGKNEKTKIIVKIQKRGQGAPGREPVISQEEQKNLMMHYYRRQEELKKLEVDEDISYLNAEWADSNSLKRQFQGVNDIKWKPR
What is the function of this protein?
Plays a role in motile cilium function, possibly by acting on outer dynein arm assembly (PubMed:26904945).  Seems to be important for initiation rather than maintenance of cilium motility (By similarity).  Required for correct positioning of the cilium at the apical cell surface, suggesting an additional role in the planar cell polarity (PCP) pathway (PubMed:26904945).  May suppress canonical Wnt signaling activity (PubMed:26904945).
What are the official names of this protein?
Cilia- and flagella-associated protein 298-B, Protein kurly-B.
What is the protein family that this protein belongs to?
Belongs to the CFAP298 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, cilium basal body. Note=Appears in cytoplasmic puncta, compatible with a centrosomal localization (By similarity).
Protein: ULAL_MOUSE
Sequence: XDNVQDSPSXQD
What are the official names of this protein?
Unknown protein from spot 2D-0014M9 of 2D-PAGE of liver tissue.
Protein: IL7RA_HUMAN
Sequence: MTILGTTFGMVFSLLQVVSGESGYAQNGDLEDAELDDYSFSCYSQLEVNGSQHSLTCAFEDPDVNITNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTPEINNSSGEMDPILLTISILSFFSVALLVILACVLWKKRIKPIVWPSLPDHKKTLEHLCKKPRKNLNVSFNPESFLDCQIHRVDDIQARDEVEGFLQDTFPQQLEESEKQRLGGDVQSPNCPSEDVVITPESFGRDSSLTCLAGNVSACDAPILSSSRSLDCRESGKNGPHVYQDLLLSLGTTNSTLPPPFSLQSGILTLNPVAQGQPILTSLGSNQEEAYVTMSSFYQNQ
What is the function of this protein?
Receptor for interleukin-7.  Also acts as a receptor for thymic stromal lymphopoietin (TSLP).
What are the official names of this protein?
Interleukin-7 receptor subunit alpha, IL-7 receptor subunit alpha, IL-7R subunit alpha, IL-7R-alpha, IL-7RA, CDw127.
What is the protein family that this protein belongs to?
Belongs to the type I cytokine receptor family. Type 4 subfamily.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 3]: Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 4]: Secreted.
Protein: OTRF1_STAAS
Sequence: MNKTKGFTKYKKMRYMPGLDGLRAIAVLGIIIYHLNKQWLTGGFLGVDTFFVISGYLITSLLLKEYDDTGIIKLKSFWIRRLKRLLPAVIVLLMVVGTATLLLKSDNIIRVKHDIIAAIFYVSNWWYIAKDVNYFEQFSFMPLKHLWSLAIEEQFYIFFPVILVTLLLTIKKRYKIGFIFWGVSIISLGLMMFIYSINGDHSRVYFGTDTRLQTLLLGVILAFLWPPFKLKNDPPKVVKYVIDSIGSLSFIVLILLFFIINDETNWIYDGGFYLISILTLFIIASVVHPSTWIAKIFSNPVLVFIGKRSYSLYLWHFAVISFVHSYYVDGQIPVYVYFIDISLTIIFAELSYRFIETPFRKEGIKALNWRPSYIPQFIRMAIVVTLLIPFMLILVGAFNKYGKDIIGEKANSFDTTIEDNYLMRIAPIDNIHIDGLVSEKKKESSDVYNNIKPLLIGDSVMVDIGESFKSSVPKSRIDGKVGRQLYQTLPLVKANYSQYKKSSDQVVLELGTNGDFTVKQLDDLLNQFGKAKIYLVNTRVPRIYEANVNRLLADAAKRKSNVTLIDWNKRSQGHSEYFAPDGVHLEYKGVLALKDEILKALKKK
What are the official names of this protein?
Putative O-acetyltransferase SAS0844.
What is the protein family that this protein belongs to?
Belongs to the acyltransferase 3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1270_BACC3
Sequence: MKLGIVIFPSKMIQDKANGLRKRYDPHYALVPPHITLKTPFETQDEQLESIVNELHTIASKTNPFTLHVGKVGSFAPVNNVIYFKVEKTPELTFLNEEMHSGFFTQEREYAFVPHLTIGQGLSDAEHADVLGRLRMKDFYYEQPIDRFHLLYQLENGTWTVHETFRLGKGNN
What are the official names of this protein?
Putative phosphoesterase BCA_1270.
What is the protein family that this protein belongs to?
Belongs to the 2H phosphoesterase superfamily. YjcG family.
Protein: GATA_CHRVO
Sequence: MTQATLKQLSQQLAAKQVSSVELASQYLDRIEALNPQLNAIVTVDREKTLAEARAADARLAAGDARALTGVPLVHKDLFCQQGWKTSCGSRMLDNFVSPYSAHVVEQCAAAGMVTLGRANMDEFAMGSSNENSFYGAVKNPWDLNAIPGGSSGGSAAAVAARLAPVATATDTGGSIRQPASHCGVTGIKPTYGVVSRYGMVAYASSLDQGGPIAQTAEDCALMLNVMAGFDARDSTSLERAKEDYARDLNQSLSGLKVGLPKEYFAAGLDADVARAVDNAVAELKKLGAEAVEISLPNTELSIPAYYVIAPAEASTNLSRYDGVRYGHRAKDYKDLVDMYEKTRAEGFGDEVKRRILVGSYVLSHGYYDAYYLKAQKIRRLIANDFKAAFEQCDVILGPVAPTAAFNIGEKSGDPVQMYLSDIYTLSVNLAGLPGMSVPAGFAANGRPIGLQIIGNYFAEARMLNVAHQFQQATDWHAKAPSL
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: METN2_RHOJR
Sequence: MTPIVRFESVTKTFSSGKKTLTAVDAVDLTIERGEIFGVIGYSGAGKSTLVRLINGLERPTSGRVVVDDVDITALSESKLRHVRAKIGMIFQQFNLFRSRTVAGNVAYPLVVAGWPRQKRRERVAELLEFVGLSDKARAYPDQLSGGQKQRVGIARALATSPDLLLADESTSALDPETTQDVLRLLRKVNRELGVTIVVITHEMDVVRAVADRVAVLAEGRVVELGTVFDVFSEPQAPASKSFVSTILRNRPEPADLERLRSRFGGRIVTADVRDGSRIGDVLSDAGGHGVRFEIVYGGITTLQDRSFGSLTLELVGPDDGVDDVIRRLRTVTDVEEVQA
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CHRR_ECO57
Sequence: MSEKLQVVTLLGSLRKGSFNGMVARTLPKIAPASMEVNALPSIADIPLYDADVQQEEGFPATVEALAEQIRQADGVVIVTPEYNYSVPGGLKNAIDWLSRLPDQPLAGKPVLIQTSSMGVIGGARCQYHLRQILVFLDAMVMNKPEFMGGVIQNKVDPQTGEVIDQGTLDHLTGQLTAFGEFIQRVKI
What is the function of this protein?
Catalyzes the reduction of quinones.  Acts by simultaneous two-electron transfer, avoiding formation of highly reactive semiquinone intermediates and producing quinols that promote tolerance of H(2)O(2).  Quinone reduction is probably the primary biological role of ChrR.  Can also reduce toxic chromate to insoluble and less toxic Cr(3+).  Catalyzes the transfer of three electrons to Cr(6+) producing Cr(3+) and one electron to molecular oxygen without producing the toxic Cr(5+) species and only producing a minimal amount of reactive oxygen species (ROS).  Chromate reduction protects the cell against chromate toxicity, but is likely a secondary activity.
What are the official names of this protein?
Quinone reductase, Chromate reductase, CHRR, NAD(P)H dehydrogenase (quinone).
What is the protein family that this protein belongs to?
Belongs to the SsuE family.
Protein: ATL31_ARATH
Sequence: MDPIKHISLPVLVLFLLLSVSAGQPGTPDQRHDPYAYSGSLSPAMAVVVVVVIAALFFMGFFTVYIRHCTGAVDGSVTPAGGARRRVTNATVARGLDAETIETFPTFVYSEVKTQKIGKGALECAICLNEFEDDETLRLLPKCDHVFHPHCIGAWLQGHVTCPVCRTNLAEQTPEPEVVVETDLEAQQQSAVPVPVVELPRVKFPRSHTTGHSVVLPGESTDRFTLRVPEELRKKIMANWKLNRSNSVFVLPRGGSSRSGKQVDRSRAKSDRWLFRKTPSFLWRNRDDGSIRLGGTGSVRGNSVTSPSGDSVRADRWAFLRNPSFLWRNTTPVPSPRVEVNNKDGEGTSSVQHIGTVGSTSGSLRLPV
What is the function of this protein?
E3 ubiquitin-protein ligase that is required for the plant C/N response during seedling growth transition.  May be involved in the early steps of the plant defense signaling pathway.
What are the official names of this protein?
E3 ubiquitin-protein ligase ATL31, Protein CARBON/NITROGEN INSENSITIVE 1, Protein SUPER SURVIVAL 1, RING-H2 finger protein ATL31, RING-type E3 ubiquitin transferase ATL31.
What is the protein family that this protein belongs to?
Belongs to the RING-type zinc finger family. ATL subfamily.
What are the subcellular locations of this protein?
Membrane; Single- pass membrane protein.
Protein: NTF3_LOXBI
Sequence: IQSTSMDQGSLSEDSMNSFIRTLIQAGIWKNKVPKQTARTKDGMQTTVKKTEAEPDVRLGFQPIVSVDAELLRQQRRFSSPRVLLSENTPLEPPPLYLMEEPMVLNRTSRRKRFAEGKSHRGEYSVCDSESRWVTDKSSAVDIRGHQVTVLGEIRMGPS
What is the function of this protein?
Seems to promote the survival of visceral and proprioceptive sensory neurons.
What are the official names of this protein?
Neurotrophin-3, NT-3.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: PROB_PROMT
Sequence: MTTWVIKIGTSLLRGNDKYTTFDVINDYCSYISKAQRNGDKIILVSSGAVGLGCHQMRFKTRPKEIISLQASAAIGQLHLMALYEKAMSSFGYKVAQILLTRSELGSRNSYNSASQTLKRLLEWDVIPIVNENDITSDEELKYGDNDTLSALVATAISADQLILLTDIDHLYSSDPKINSKAKPIKDINNSKELNNLELANEQTSWGTGGIKTKLTAAKIATESGIKVQLADGRDPKILGELLDGKKIGTVFHPNPNPIGNRKSWLAHAIKPVGEIHLDDGASEAIKNKGASLLLVGVKKVSGDFIANQPVKVINTEGEEFAKGICSMSSDAIKIGINSRSETTGSPLVIHRDVLVLTSE
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPA_MICLC
Sequence: MLPRDRRVRTPAEFRHLGRTGTRAGRRTVVVSVATDPDQTRSTSPSAPRPRAGFVVSKAVGNAVTRNRVKRRLRAVVAEQMRLPPLRDLPVLVQVRALPAAAEADYALLRRETVGALGKALKPHLPAASEHA
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: SYH_METSB
Sequence: MTDDKTTPARASAKLPRGFGDRGPAEIAATEKMLAAIRASYELYGFEAVETPFIEFTDALGKFLPDLDRPNEGVFSFKDDDESWLSLRYDLTAPLARFVAENFDKLPKPYRSYRAGYVFRNEKPGPGRFRQFMQFDADTVGAPSVAADAEMCMMAADTLERLGVKRGDYVIKVNNRKVLDGVLEAIGLGGEENAGRRMTVLRAIDKLDKFGPEGVALLLGPGRKDESGDFTKGAGLERTAVERVLNYVAAQGEGTAQMLGVLRASVAGSQRGEEGVAELAEIAALIDAAGFSARIRIDPSVVRGLEYYTGPVFEAELTFEVQGEDGKPVRFGSIGGGGRYDGLVGRFRGENVPATGFSIGVSRLYSALKAVGSPIVSAASQPGPVVVLVLDREHLARYQGFVTALRSADIRAELYLGGSGMNAQLKYADKRGSLCAVIQGSNERDHAEGARVTIRDLALGAELAGASKDRADYLELRAKAQFTVAEQNLVDAVREVMARRS
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQRC_VIBAL
Sequence: MASNNDSIKKTLGVVIGLSLVCSIIVSTAAVGLRDKQKANAVLDKQSKIVEVAGIDANGKKVPELFAEYIEPRLVDLETGNFTEGNASTYDQREASKDAERSIALTPEEDVADIRRRANTAVVYLVKDQDEVQKVILPMHGKGLWSMMYAFVAVETDGNTVSAITYYEQGETPGLGGEVENPSWRDQFIGKKLYNEDHQPAIKVVKGGAPQGSEHGVDGLSGATLTSNGVQHTFDFWLGDKGFGPFLAKVRDGELN
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit C, Na(+)-NQR subunit C, Na(+)-translocating NQR subunit C, NQR complex subunit C, NQR-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the NqrC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: HSLO_ACAM1
Sequence: MADQLIRATAADDGIRAVGVITTRLTEDARQRHGLSYVATAALGRTMSAGLLLASSMKQAEARINLRIRGDGPLQGILVDAGLDGTVRGYVTNPGVELPPNAKGKLDVGGAVGKGFLYVIRDMGYGYPYSSTVELVSGEIGEDVTHYLVTSEQTPSALALGVFVGAQGVTASGGLLIQVLPKAAEDPALVELLESRLAHLQGFTPLLQAGKTLPDIFTDLLGDMGLKIFPQTQMVQFQCRCSTERVLGALKMLGQDELLDMIEKDDGAEATCDFCGEVYQVTSDQLGKLIDDLKTEAGA
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VAX1_DANRE
Sequence: MEVRYSQDSESGMLLKNGLKEGKEGKDSQGSISKTFLKDQQESFSPSGAVENCEKSRASSGDPDYCRRILVRDAKGSIREIILPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQGKDSELRSVVSETAATCSVLRLLEQGRLLTPPGLPGLLPHCGSSSLGSALRGPSLGITANGGSSSSSRSSAGSSGTAGGSPPLPTVTSSGTVTGLQGSPPAHGLFSFPMPSLLGSVASRISSTPLGMAGSLAGNLQELSARYLCSSAFEPYSRTNGKEALDKKVLE
What is the function of this protein?
Transcription factor that is required for closure of the choroid fissure and together with Vax2 is required for optic nerve differentiation and to limit retinal development to the optic cup.
What are the official names of this protein?
Ventral anterior homeobox 1.
What is the protein family that this protein belongs to?
Belongs to the EMX homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLMU_TROW8
Sequence: MKSDLAIVILAAGRGTRMRSSTPKVLHNIAGLPMVAHVLRGAQLLKPCKTIVVFRDVRVEQYIRNTFPDVLTVAQSDALYGTGFGVFSAIPWIRSESYGNTYPNTRHESHAEYELDACDLDTCNPASDRLNDQESLKGGRHIHTKSGDVTNNKPFPSRVLILYADVPLVPFQLLEELVRKPLKQAVGAIVTTHLDNPKGYGRVMRDNLGSIAKIIEDSNILPEQSINEVNTGVGIFDTEYLQDALNKLLKCHIAHSPNQDCVTNQDCVTNQDCVTNQDCVTNQDCVTNQDCVPAAHTEAHVLSPKVIVTEQIHKKAESEHQHAGQWMCRQDTVGAQNTKEEMRLTDIVEYFYNNGLRVNSITTSDSELLLGVNNRVQLAKTEKILNDQIIKRWQLYGVTIKSPETTWIDSTVQLSEDVLILPGCILSGRTRIEEGAVIGPFATISDSFIGKNTIVKRAEIIDARIEEGAVIGPFAFIRPGTVIGKDSKVGTFVEIKQSNIGPESKVPHLSYIGDANIGSHVNIGAGNIFANYDGKLKHETCIDDGVKTGAGNVFVAPVKVGRGAYTGAGSVIRDDIEEGALSLTELKQKTIPKWAENRGDG
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_STREM
Sequence: MIQQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVKQATPGGAVKKGDVVKAVIVRTKSGARRPDGSYIKFDDNAAVIIRDDKTPRGTRIFGPVARELREGGYMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: NADA_AQUAE
Sequence: MVQLALKEEKELTKEEIKELQKEVRRLAKEKNAVILAHYYQRPEVQDIADFVGDSLELARKASQTDADIIVFCGVRFMCETAKIVNPEKKVLHPNPESGCPMADMITAKQVRELREKHPDAEFVAYINTTADVKAEVDICVTSANAPKIIKKLEAKKIVFLPDQALGNWVAKQVPEKEFIIWKGFCPPHFEFTYKELEKLKEMYPDAKVAVHPECHPRVIELADFVGSTSQILKYATSVDAKRVIVVTEVGLKYTLEKINPNKEYIFPQSMNYCGTVYCCTMKGITLPKVYETLKNEINEVTLPKDIIERARRPIERMLELS
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_SHEON
Sequence: MSRVAKAPVSIPAGVEVTLNEQTLTVKGAKGSLTRVINNAVNVVIENGVIKFLPVEGAVGAWAQAGTTRALVNNMVVGVSQGFERKLKLVGVGYRAKLVGADIDLTLGFSHPLVHKLPAGVTAECPSQTDIVLRGVDKQLIGQVAAEIRGYRPPEPYKGKGVRYDDEEVRRKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.