PharMolix/UniProtQA huggingface dataset:
Protein: STING_XENTR
Sequence: MACVLAIGSILFVWILGKGKYSGAQLIYRMATNFAISQGCCLVTCACELTEEIKHLHTRYNGHYWRALKASFNLSCAAFVTAILCYVFYEPKLMASLPLTIDITLTLLSWLFCWILGIQGPTPATISEITEIKQLNVAHGLAWSYYVGYLQFVLPALKESIQKFNEENHNLLKFPETCRLHILIPLSCRLYGDLKDVDENITFLKEIPPLYIDRAGIKGRVFKNNVYRILDEDGRPYNCIVEYATPLASLLKMTDIPSAAFSADDRLQQTKLFYRTLKDILENAHELQNTYRLIVYEDFPETKDHSRHLLSQEILKHIRQQHSEEYSML
What is the function of this protein?
Sensor of cytosolic DNA from bacteria and viruses that promotes autophagy.  Acts by recognizing and binding cyclic GMP-AMP (cGAMP), a messenger produced by CGAS in response to DNA in the cytosol (PubMed:26300263, PubMed:30842662).  Following cGAMP-binding, promotes the formation of autophagosomes, leading to target cytosolic DNA for degradation by the lysosome (PubMed:30842662).  Exhibits guanine base-specific ligand recognition.  Binds 3'-3'linked cGAMP, 2'-3' linked cGAMP and 3'-3' linked c-di-GMP with much greater affinity as compared to 3'-3' linked c-di-AMP (PubMed:26300263).  Lacks the C-terminal tail (CTT) found in other vertebrate orthologs which is essential for interferon signaling (PubMed:26300263).
What are the official names of this protein?
Stimulator of interferon genes protein, STING, Transmembrane protein 173.
What is the protein family that this protein belongs to?
Belongs to the STING family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cytoplasm, perinuclear region. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein. Note=In response to double-stranded DNA stimulation, translocates from the endoplasmic reticulum through the endoplasmic reticulum-Golgi intermediate compartment and Golgi to post-Golgi vesicles, where the kinase tbk1 is recruited (PubMed:30842662). Upon cGAMP-binding, translocates to the endoplasmic reticulum-Golgi intermediate compartment (ERGIC) in a process that is dependent on COPII vesicles; STING1-containing ERGIC serves as a membrane source for LC3 lipidation, which is a key step in autophagosome biogenesis (By similarity).
Protein: DNLJ_BRUA1
Sequence: MSDISVEKLTELEAAAELERLARAIAHHDELYHAKDRPEISDAAYDALKRRNEAIEAHFPALVRDDSPSRRVGAAPALATFAPVVHARPMLSLDNAFSDEDVRDFVGSVYRFLGQLPDDSIAFTAEPKIDGLSMSIRYENGILVSGATRGDGTTGENVTANIRTIAEIPNRLPAGAPAVVEVRGEVYMAKSDFLTLNAQMEAEGKQTYVNPRNTAAGSLRQLDAKVTASRKLRFFAYAWGEMSDMPADTQLGMVEVFRQWGFPVNPLMKRFNSVDGLLAHYRAIGMERPTLDYDIDGVVYKVDRLDLQTRLGFRSRSPRWAIAHKFPAEQALTILRGIDIQVGRTGALTPVARLEPITVGGVVVTNATLHNEDYIKGIGQKGEPIREGRDIRIGDSVIVQRAGDVIPQIVDVVLEEGKKRGEPYQFPHVCPACGSHAVREEGEAVRRCTGGLICPAQAVERIRHFVSRNAFDIEGLGEKQVEFFFNAEDPALCIRSPADIFTLKKRQENSLTKLQNIEGFGATSVKKLYDAIDARREIALHRFLFGLGIRHVGEVNAKRLARAYLSYAAFEKAALEAVPPKEGDRTDKGSEAWQDMLAVEGIGSIVAEAVVDFYGEPHNREVLAALLAEVTPLDEEARVATGSPVEGKTVVFTGSLERMSRDEAKAMAERHGAKTAGSVSKKTDLVVAGPGAGSKLAKATELGIEVINEDDWFKLVGED
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: RHA1_EMENI
Sequence: MKSIALTSLSLLPSALAQTIYLAGDSTMASSTPGWGDYIADSVSVEISNQAIGGRSARSYTREGRFQAIADVLQAGDYVVIEFGHNDGGSLSNDNGRTDCPGDGDETCETVYNGVAETVLTFPAYIENAALLFLEKGANVLISSQTPNNPWESGTFSYTPNRFVGYAELAAQRAGVDYVDHGAYTASIFEALGADTVNSFYPNDHTHTNAEGSSVVADAFLKAVVCSGVALNDVLTRTDFDGECL
What is the function of this protein?
Plays a key role in the degradation of rhamnogalacturonan in the cell wall.  Involved in degradation of pectin.
What are the official names of this protein?
Rhamnogalacturonan acetylesterase, RGAE.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family.
What are the subcellular locations of this protein?
Secreted.
Protein: HEM1_FRATF
Sequence: MALISLAIDYKKSPIEVRSEFALSGLDVSMLYRSILAIDNVVHAVILSTCNRTEVYLEISDLIVVDDILVWWQGYVRNPNYKIKDYFKLRQGTEVIMHLMKLACGLESMVLGEPQILGQVKDSYTLSKKNHAIGKELDRVFQKVFATAKRVRSETRIGYCPVSVAFSAITLAKRQLDNISSKNVLIIGAGQTGELLFRHVTALAPKQIMLANRTIEKAQKITSVFRNASAHYLSELPQLIKKADIIIAAVNVLEYIVTCKYVGDKPRVFIDISIPQALDPKLGELEQNVYYCVDDINAVIEDNKDKRKYESSKAQKIIVKSLEEYLEKEKAIISNSAIKELFQKADGLVDLSLEKSLAKIRNGKDAEEIIKRFAYEIKKKVLHYPVVGMKEASKQGRSDCLVCMKRMFGLNVEK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: NUOD_RHOPB
Sequence: MPEGALRNFTINFGPQHPAAHGVLRLVLELDGEIVERVDPHIGLLHRGTEKLIEAKTYLQAIPYFDRLDYVAPMNQEHAFCLAAEKLLDIAVPRRAQLIRVLYCEIGRILSHLLNVTTQAMDVGALTPPLWGFEEREKLMMFYERASGSRMHAAYFRVGGVHQDLPPKLVDDIEAWCVAFPQVIDDLDRLLTGNRIFKQRNVDIGVVTLAQAWEWGFSGVMVRGSGAAWDLRKSQPYECYAELEFDIPIGKNGDCYDRYCIRMEEMRQSVRIMQQCIAKLRAPDGGGPVAVQDNKIFPPRRGEMKRSMESLIHHFKLYTEGFRVPAGEVYVAVEAPKGEFGVFLVSDGSNKPYKCKIRAPGFAHLQAMDFISRGHLLADVSAILGSLDIVFGEVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: BAMB_ALTNA
Sequence: MFHNTCGRKGRFARAMGMALAISVTLSGCSTVSDWFADEEELEIRRLKPIDAKFTPSVKWDRDIGDGVDHYFSRLRPVYAYENLYAADRHGSVVAMNPENGDVLWERDFAVFEGDGWWDSIARLWRSGASARIGGISVADRLLFVGTENGVVMALDYETGETKWEASVPGEVLAAPSADEGILVVNTGAGTLFGFDTRTGEQLWRHEGDTPPLTLRGISGPVAANGGALIGTPTGKLQVNLLESGILAWETVIATPTGATELERIVDLDTTPVLFGGTIYTVSYNGTLAAVELRSGRIIWKREYGSYRNLSIEGNSIFVVDNNSNIYALDRRNGVELWSQGSLKSRSVTAATPVGEHIVVGDNWGFVHWIEQETGQIVARVDVGGDDEDDAIYDAPLNVDGVVVTMTRNGVVAAISTL
What is the function of this protein?
Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
What are the official names of this protein?
Outer membrane protein assembly factor BamB.
What is the protein family that this protein belongs to?
Belongs to the BamB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: Y795_STAES
Sequence: MEYQYPLDLDWTNDEMMKVIHFFNKIENYYEASVKGDEVLNAYKNFKHIVPGKADEKQIFKEFENKSGYNSYKVVQEIKKNPNQTLFSKDFD
What are the official names of this protein?
UPF0223 protein SE_0795.
What is the protein family that this protein belongs to?
Belongs to the UPF0223 family.
Protein: YME2_NEUCR
Sequence: MISAHILSRQATRPGHRGPRFTTHSTALLVQRSLGQGLPLAHRRTTRAWESTSSSTASTGSHKESGHIETAPHESLLFFNNLFPLKLSSILIWRPWTSEDLLQRFEQSSYSFIDPIRLVKRAINTHDQVPIEVTQIIPRLKDGGAFVKFTHPSDMSAAVVESKLSELLQNNPIKPWFNPFGRVKAGLVEGVPWLEDLYRLPRSRIRVEFVAAKDDASPAELSQETLYSIFRKFGKITEITSQPTDSKVLPRFAYIDFVLVRDAIMARNCMHGFVLREQGSKNATKLRLSYEQRVKAHHIWAWFTSHPRIVIPLVAALIAAFTVAVFDPIREFFVKAHVQKYFEFTNSRLYKWFKSQTSDILAFRRRKTEDAGLNALFTHRKDLIDSIQTGLLESVDTFTVVHGPRGSGKKELILDQVLKERSNVLHIDCKPVVEARGEAGTIGRLAFEVGYRPVFSWSNNISSLVDLAVQSTTGVKANFSENLESQVVKILQTTASALKQVGLSERKKEDKDADLSEDAYLEAHPERRPVIVIDHFLHKSEEKGVIYDRIADWAAALVQSNIAHVIFLTDDASYSKPLQRSLPDRVFRSVTLGDLSPDVAKKFVISQLQTDTKFAHDGQQKDSESGDQDNDNKNQKKDSNTPAPLDPTLLKELDTCITALGGRLTDLQVLARRLKIGQSPRKAVQEIIDSTASDILRMFLLSKSSTSDRKYTTEQAWYLISHLAASPSSSIPYNSVLLSNTFASSPETALEALANAELITVKSQNGMPSEIKAGKPVYQAAFQKLASDEKVKARMDLLVLTELAKMETQKIEKVEQELVMLQGLMARRPGDVSERVEYLLEKMKGGQARLKGLEKEMGVVKGQMVKG
What is the function of this protein?
Plays a role in maintaining the mitochondrial genome and in controlling the mtDNA escape.  Involved in the regulation of mtDNA nucleotide structure and number.  May have a dispensable role in early maturation of pre-rRNA (By similarity).
What are the official names of this protein?
Mitochondrial escape protein 2, mRNA-splicing protein 45.
What is the protein family that this protein belongs to?
Belongs to the YME2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: LSRD_ECOHS
Sequence: MRIRYGWELALAALLVIEIVAFGAINPRMLDLNMLLFSTSDFICIGIVALPLTMVIVSGGIDISFGSTIGLCAIALGVLFQSGVPMPLAILLTLLLGALCGLINAGLIIYTKVNPLVITLGTLYLFAGSALLLSGMAGATGYEGIGGFPMAFTDFANLDVLGLPVPLIIFLICLLVFWLWLHKTHAGRNVFLIGQSPRVALYSAIPVNRTLCALYAMTGLASAVAAVLLVSYFGSARSDLGASFLMPAITAVVLGGANIYGGSGSIIGTAIAVLLVGYLQQGLQMAGVPNQVSSALSGALLIVVVVGRSVSLHRQQIKEWLARRANNPLP
What is the function of this protein?
Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import.  Probably responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
Autoinducer 2 import system permease protein LsrD, AI-2 import system permease protein LsrD.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYO12_VIOOD
Sequence: GLPICGETCVGGTCNTPGCSCSWPVCTRN
What is the function of this protein?
Probably participates in a plant defense mechanism.
What are the official names of this protein?
Cycloviolacin-O12.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Moebius subfamily.
Protein: QUEC_LYSSC
Sequence: MKQEKAIVVFSGGQDSTTCLFWAKERFAEIEAVTFNYGQRHRLEIECAEQIAEELGIKHHILDMTLLNQLAPNALTRQDIKVEDGQNGELPSTFVPGRNLLFLSFAGVLASQIGAKHIVTGVCETDFSGYPDCRDVFIKSLNVTLNLSMDNSFVIDTPLMWLNKAQTWELADQFGALEFVRERTLTCYNGVIADGCGECPACKLRKKGLDEYLSYRKEF
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: ESM1_DROSI
Sequence: MMSQTLTLCCLGLVACVYGNTVSTNDTACPTFCPSIYKPVCGTDGQNFKEFASTCNLLSHNCRRERNSVQAYAATDAAWCSSEFVENLHEKLGNFKLEVKECFKPCSMIYQPVCITNGKYRAELANSCLLENFNCALQVSGAQPAELFRLLREEKC
What are the official names of this protein?
Enhancer of split M1 protein, E(spl)m1, Kazal-type protease inhibitor m1.
Protein: RAS_CRYNB
Sequence: MSKAQFLREYKLVVVGGGGVGKSALTIQFIQSHFVDEYDPTIEDSYRKQCIIDEEVALLDVLDTAGQEEYGAMREQYMRTGEGFLLVYSITSRSSFEEVSTFHQQILRVKDKDYFPVVVVANKCDLEYERQVQPHEGRDLAKRFNAQCIETSAKQRVNVDEAFIAVVRAIRRYQKESGPPQAVNAPAKSQMSAVGGRAAEKDDHVDKGCCRGCVVL
What are the official names of this protein?
Ras-like protein.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: GSA_SALSV
Sequence: MSKSENLYSAARELIPGGVNSPVRAFTGVGGTPLFIEKADGAYLYDVDGKAYIDYVGSWGPMVLGHNHPAIRNAVIEAAERGLSFGAPTEMEVKMAELVTNLVPTMDMVRMVNSGTEATMSAIRLARGFTGRDKIIKFEGCYHGHADCLLVKAGSGALTLGQPNSPGVPADFAKHTLTCTYNDLASVRAAFEQYPQEIACIIVEPVAGNMNCVPPLPEFLPGLRALCDEFGALLIIDEVMTGFRVALAGAQDYYGVVPDLTCLGKIIGGGMPVGAFGGRRDVMDALAPTGPVYQAGTLSGNPIAMAAGFACLNEVAQPGIHETLDELTTRLAEGLLEAAEEANIPLVVNHVGGMFGIFFTDAESVTCYQDVMACDVERFKRFFHLMLEEGVYLAPSAFEAGFMSVAHSMDDINNTIDAARRVFAKL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2097_LISMH
Sequence: METNQILETIRMIEEEKLDIRTITMGISLLDCMDGDGEVARKKIYQKIVTKARNLVAVGEAIESEFGIPIINKRISVTPIAIIAGSSADTDYVGFAKTLDAAAKEVGVNFIGGYSALVQKGYTKGDEILIRSIPQALAQTERVCSSVNVGSTRTGINMDAVRQMGEVIKETADLTADTQGLGCAKLVVFANAVEDNPFMAGAFHGVGEADCVINVGVSGPGVVKRAIEKVKGEPFDIVAETVKQTAFKITRMGQLVGQVASEKLGVPFGIVDLSLAPTPAIGDSVAHILEEMGLEMVGTHGTTAALALLNDAVKKGGVMACGHVGGLSGAFIPVSEDAGMIEAVQQGALNLEKLEAMTAICSVGLDMIAVPGDTTAETLAAMIADEAAIGVINNKTTAVRVIPASGTKVGDMVEFGGLLGTAPVMPVNGKSSVDFIARGGRIPAPIHSFKN
What are the official names of this protein?
UPF0210 protein LMHCC_2097.
What is the protein family that this protein belongs to?
Belongs to the UPF0210 family.
Protein: RL23_PSEPF
Sequence: MNQERVFKVLLGPHVSEKATVLADKKGQFVFKVATDATKLEIKKAVESLFSVKVERVTTLNVLGKSKRTARGLGKRNDWKKAVISLQPGQDLDFSSSAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: YVAP_VACCC
Sequence: MKYILYSRCSFSFSFISNHLTPDGPSKIGWLDKGFIISSSTLYFSMTSNVVCETTFPAGKHIPGAGDGNCFVYPSNFDVEKDCLMVFIE
What are the official names of this protein?
Uncharacterized 9.9 kDa protein.
Protein: RR3_CUSRE
Sequence: MGQKINPLGFRLGTTQDHHSLWFSQPKNYSESLQEDKKIRDFINNYVKKNMRKASGAEGIARISIQKRIDLIQVVIFMGFPKFLIETRPQGIEELQRTLQKEFNCGNQKLNITITRIEKPYGNPNILAEFIAVQLKNRVSFRKAIKKAIELAEQADTKGIQVQIAGRIDGKEIARVEWIREGRVPRQTIRANLDYSSYPVRTIYGVLGIKIWIFID
What are the official names of this protein?
Plastid 30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Plastid.
Protein: TPDR2_COMSP
Sequence: MNHQIHIHDSDIAFPCAPGQSVLDAALQAGIELPYSCRKGSCGNCASTLLDGNIASFNGMAVRNELCASEQVLLCGCTAASDIRIHPSSFRRLDPEARKRFTAKVYSNTLAAPDVSLLRLRLPVGKRAKFEAGQYLLIHLDDGESRSYSMANPPHESDGITLHVRHVPGGRFSTIVQQLKSGDTLDIELPFGSIALKPDDARPLICVAGGTGFAPIKSVLDDLAKRKVQRDITLIWGARNPSGLYLPSAIDKWRKVWPQFRYIAAITDLGDMPADAHAGRVDDALRTHFGNLHDHVVHCCGSPALVQSVRTAASDMGLLAQDFHADVFATGPTGHH
What is the function of this protein?
Component of the terephthalate 1,2-dioxygenase multicomponent enzyme system which catalyzes the dioxygenation of terephthalate (TER/TPA) to 1,2-dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylic acid (DCD).  TphA1 probably reduces TphA2A3.  It can also use 2,5-dicarboxypyridine (PDC) and 1,4-napthalenedicarboxylic acid (NDC) as substrates, and preferentially uses NADPH which is the physiological electron donor.
What are the official names of this protein?
Terephthalate 1,2-dioxygenase, reductase component 2, TER dioxygenase system, TERDOS, TPADO reductase component.
Protein: CCN1_HUMAN
Sequence: MSSRIARALALVVTLLHLTRLALSTCPAACHCPLEAPKCAPGVGLVRDGCGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQNGESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIKDPMEDQDGLLGKELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKCIVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQPVYSSLKKGKKCSKTKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVMMIQSCKCNYNCPHANEAAFPFYRLFNDIHKFRD
What is the function of this protein?
Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion.  Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5.  CCN1-mediated gene regulation is dependent on heparin-binding.  Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1.  Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-v/beta-5 and cell proliferation through integrin alpha-v/beta-3.
What are the official names of this protein?
CCN family member 1, Cellular communication network factor 1, Cysteine-rich angiogenic inducer 61, Insulin-like growth factor-binding protein 10, IBP-10, IGF-binding protein 10, IGFBP-10, Protein CYR61, Protein GIG1.
What is the protein family that this protein belongs to?
Belongs to the CCN family.
Protein: NPH2_FOWPN
Sequence: MTTNDLFSIYAFSNMYDIFPRKYSQKELEEYHRKNPLFFSYTIFPVIKHRWSKAYICFQNNVYMLNIELDTSKPYDRVPIQHLIDIRPISTDIKKEIYKISDKTFITFECYSYLKCKGYNSIYDITLDDKRGLLSAGNILSIFSSNKQMPEKSSIGILKNPKPFTVIKFKSLSLITQLQIFELLRKRKQIVVTGSTGIGKTSQLPKVIMWYNYLFGGWDNLDRVRFDYISRPIVLSLPRVALVKSNGINFLQSLGFSDFEGSPVELRYGGKTEHTTRQHDGIVLSTNKLTSYSLSNYNIIIVDEIHEHDRIADIIISVLRKNIDTIHSLVLMSATLEDDRDRLQEFLPDVEFYHIEGPVLYSIKEIYVKNKYSYDSKAYTEEEKKNISTTLNWCRPRNGMCGILFLASVSQCISYKKYLEKSNSDMDFIIIHGKIPDITEVLNAVQRPGRERPCILVSTPYLESSITIRTATHVYDTGRVYVPKPFGGDQLFISKSMMTQRKGRVGRVSKGIYVYFYDMCLLKPIKSIDHEFLYEYIVYAKKFKLSLPNDLLVIPSDKDMLKKSEEYIKSFNISFDRLFEIYVNYFVNMVEYVKIYNKGGKKAENLDMFERNDILTGETLKDIKNLQLLVKINTTTRRKKMYCYKGEILFGPYMNTVIRLSSKQLYRNYVYMLTERSFTLYR
What is the function of this protein?
NTP-dependent helicase that catalyzes unidirectional unwinding of 3'tailed duplex RNAs and plays an important role during transcription of early mRNAs, presumably by preventing R-loop formation behind the elongating RNA polymerase.  Might also play a role in the export of newly synthesized mRNA chains out of the core into the cytoplasm.  Required for replication and propagation of viral particles (By similarity).
What are the official names of this protein?
RNA helicase NPH-II, Nucleoside triphosphatase II, NTPase II, Nucleoside triphosphate phosphohydrolase II, NPH II.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
What are the subcellular locations of this protein?
Virion. Note=Localizes to the virion core.
Protein: RS5_WOLSU
Sequence: MEINRDEFKEVVVNIGRVTKVVKGGRRFRFNALVVVGNKNGLVGFGLGKAKEVPDAIKKAVDDAFKNIIKVNVKGTTIAHDIEHKYNASKILLKPASEGTGVIAGGSARPVIELAGIKDILTKSLGSNNPYNVVRATIDALSRIKA
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: MHPB2_PSEPU
Sequence: MNAYLHCLSHTPLIGHFDPNQDVLDEVAEVVRAARARIEAFNPELVVLFAPDHYNGFFYDVMPPFCLGMEAEAIGDFGSLAGTLSVPKDVAEACAESVLTSGIDLAVSYRMQVDHGFAQPLDFLLGGLDKYPVLPVFVNCVAPPLPTFERVRLLGDAIGRFTRGLNKRVLFLGSGGLSHQPPVPELAKVDARMADRLMGSGRNLPPEERDARTQRVVVAAERFVENQNTLHPLNPKWDRYFLDVVEQDLLSQLDDLSNAHLSELAGKSTHEVKAWVAAFSALSAHGAYTATDRYYRPIPEWIAGFGSISAHTQR
What is the function of this protein?
Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6-ketononatrienedioate, respectively.
What are the official names of this protein?
2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase 2, 3-carboxyethylcatechol 2,3-dioxygenase 2.
What is the protein family that this protein belongs to?
Belongs to the LigB/MhpB extradiol dioxygenase family.
Protein: PSBL_OENPA
Sequence: MTQSNPNEQDVELNRTSLYWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: MURG_ECOK1
Sequence: MSGQGKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADRMEADLVPKHGIEIDFIRISGLRGKGIKALIAAPLRIFNAWRQARAIMKAYKPDVVLGMGGYVSGPGGLAAWSLGIPVVLHEQNGIAGLTNKWLAKIATKVMQAFPGAFPNAEVVGNPVRTDVLALPLPQQRLAGREGPVRVLVVGGSQGARILNQTMPQVAAKLGDSVTIWHQSGKGSQQSVEQAYAEAGQPQHKVTEFIDDMAAAYAWADVVVCRSGALTVSEIAAAGLPALFVPFQHKDRQQYWNALPLEKAGAAKIIEQSQLSVDAVANTLAGWSREILLTMAERARAASIPDATERVANEVSRAARA
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: VP2_FCVUR
Sequence: MNSILGLIDTVTNTIGKAQQIELDKAALGQQRELALQRMNLDRQALNNQVEQFNKILEQRVQGPLQSVRLARAAGFRVDPYSYTNQNFYDDQLNAIRLSYRNLFKN
What is the function of this protein?
Minor structural protein present in one or two copies per virion.  Does not seem to play a role in capsid assembly, but is essential for production of infectious virus.
What are the official names of this protein?
Protein VP2, Minor capsid protein.
What is the protein family that this protein belongs to?
Belongs to the vesivirus VP2 protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: HCT2_CHLPN
Sequence: MIGAQKKQSGKKTASRAVRKPAKKVAAKRTVKKATVRKTAVKKPAVRKTAAKKTVAKKTTAKRTVRKTVAKKPAVKKVAAKRVVKKTVAKKTTAKRAVRKTVAKKPVARKTTVAKGSPKKAAACALACHKNHKHTSSCKRVCSSTATRKHGSKSRVRTAHGWRHQLIKMMSR
What is the function of this protein?
Might have a role in establishing the nucleoid structure of elementary bodies.
What are the official names of this protein?
Histone H1-like protein HC2, HC2 nucleoprotein.
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family. HCT subfamily.
Protein: TRPD_CLOAB
Sequence: MLKDAIKKIVRFETLSENEAYGAMNEIMDGKVSEIDMAAFLTGLRMKGEEVEEILGCARAMKEHAVKVEVNNLYAIDTCGTGGDGGKTFNVSTCSSIIAAAGGVKIAKHGNRAGSSKSGSADVLTELGVSINLKPEEVKREIEEKGMAFIFAQSYHKAMKNVAPVRKSLGFKTIFNLLGPLTNPCNIGGQVLGVFDQKLTHPLAEVLLKCGLEKAMVLNGCDGLDEITITGSTFVSEIKDGRIKDYVIKPEDFGIKRSKIEDVRGGTPKENAEIIIDILKGKGGPKRDIAVLNAAAALYIGKITENLKDGVRLACNIIDSGKAFQKYEELV
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.