PharMolix/UniProtQA huggingface dataset:
Protein: TRMB_BARHE
Sequence: MIDHNIRTGKAFFGRRKGKRLRNSQLVLIKKLFPTLDINLNNSVPLNLTSLFSRKVKEVRLEIGFGGGEHLLHEMKHFPQTGFIGIEPFINGMAKMLMSLEEHKQYQNQLRLYNDDATGLLDWLPNASLDGIDLFYPDPWPKKKHWKRRFINMKNLNRFARVLKTGKKFRFASDIESYVNWTLYHCSNHHSFEWEAKNPKDWKTPYTLWSGTRYEAKALREGRAPTYLTFIKK
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: TRMFO_CERSK
Sequence: MAESLHIVGAGMAGSEAAWQAAEMGVPVVLHEMRPKVGTFAHRTGQFAEMVCSNSFRSDDDERNAVGLLHWEMRAARGLIMEMAAAHRLPAGGALAVDRDPFAESVTARLRAHPLISVVEEEVAELPSSGNWIVATGPLTSSALAESLRALTGAEALAFFDAIAPIVYAETIDMEVAWRQSRYDKGETEDERTAYINCPMNREQYEAFIDALLAAEKTEFHEGETAGYFDGCLPIEVMAERGRETLRHGPMKPVGLTNAHRPEEKAYAVVQLRRDNKLGTLYNIVGFQTKMKYGAQTAVFKMIPGLENASFARLGGIHRNTFLNSPTLLDDRMRLKLRPNIRFAGQVTGVEGYVESAAMGLLAGRMAAAEILGRDLPPPPPETAMGALVTHITGGAEAKSFQPMNVNFGLFPPIDARGGRRGRKDRYKAYTDRAKAAFTEWLGA
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROA_YERP3
Sequence: MNLLEHMGKAAKQASWQLAMLSTAKKNQALAVIANLLESESQTILQANERDMAAARESGMSEALLDRLLLTPARLAAIANDVRQVCRLNDPVGRVIDGSLLDSGLKLERRRVPLGVIGVIYEARPNVTIDVASLCLKTGNAVILRGGKETHHTNQATVNVIQRALEQCGLPAAAVQAIESPDRQLVNELLRLDRYVDMLIPRGGASLHKLCREQSTIPVITGGIGVCHTFVDENADFEKALLVIENAKIQRPSACNSLETLLVHQAVAKTFLPLLSARMHAFGVTLHASPLAMPYLADGKAKVVAVEAADYDDEWLSLDLNVDIVTDIDAAIDHIREHGTSHSDAILTRSLSHAEYFVRAVDSSAVYVNASTRFTDGGQFGLGAEVAVSTQKLHARGPMGLDALTTYKWIGYGDDLVRS
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSZ_SHIBS
Sequence: MVSSFTSAPRSGFYYFAQGWKLVSQPGIRRFVILPLLVNILLMGGAFWWLFTQLDVWIPTFMSYVPDWLQWLSYLLWPLAVISVLLVFGYFFSTIANWIAAPFNGLLAEQLEARLTGATPPDTGIFGIMKDVPRIMKREWQKFVWYLPRAIVLLILYFIPGIGQTVAPVLWFLFSAWMLAIQYCDYPFDNHKVPFKEMRTALRTRKITNMQFGALTSLFTMIPLLNLFIMPVAVCGATAMWVDCYRDKHAMWR
What is the function of this protein?
High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake.  Provides the sulfur source for the cysteine synthesis pathway.
What are the official names of this protein?
Sulfate transporter CysZ.
What is the protein family that this protein belongs to?
Belongs to the CysZ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CSRA_SHESR
Sequence: MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHREEIYQRIQSEKSGTPSEGGNF
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFB_BRUSU
Sequence: MKFTLSWLKDHLETDATLDEIVEKLTDIGLEVESVDDRAAFRAFTIARVLTATRHPDADKLQVLSVDTGDGKPVQVVCGAPNARAGLVGVLGRPGDYVPGLDVTLSVGKIRGVESFGMMCSERELELSDEHNGIIDLAENAPVGTSFAAYMGLDDPIIEIGLTPNRADCTGIRGIARDLAAAGLGTLKNTLPDAVKGEGETPVKVILDQDAGNPFCTGFALRMVKGVKNGPSPKWMQQRLKAIGLRPINALVDITNYVTFDQGRPLHVFDAAKVKGNLTVRTARDGETILALDQREYKLNAGMYVIADENGPESIAGIMGGEHSGCDENTVDVLIESALWDPRMIARTGRELGIVTDARYRFERGVDPEMMVPGAEIATKLVLELCGGQPTVLDVVGYKPHTARVIDFPVTEVKRLTGLDVSYEDAFDILKRLGFGVEGDGKTIRATVPSWRGDVEGKADLVEEVMRIHGINRIDPQPLPSHGAVNGRILTTLQIRTRHARRMLASRGMMEAVTYSFISEAQAKAFGGGKPELKLANPIAADMSDMRPSLLPGLLAAAQRNADRGFGDIALFEVSGIYEGDTPDKQRRVAGGVRRGTAKVEGAGRFWAGNAAPVGVFDAKADALAALEAAGAPVDRIQIEAGGPEWLHPGRSGTLKLGPKVVLGTFGEFHPDTLEALDVSGALCGFEVYLDAIPEPKAKSARTKPALSLSLFQSLKRDYAFVVDAAVEAGNVVKAVSSADKKLIVGVQVFDIFTGASLGEGKKSIAVEVLLQPQDRTLTDEDLEALSKQIVASVAKQTGGVLRG
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG085_VACCC
Sequence: MIVLPNKVRIFINDRMKKDIYLGISNFGFENDIDEILGIAHLLEHLLISFDSTNFLANASTSRSYMSFWCKSINSATESDAIRTLVSWFFSNGKLKDNFSLSSIRFHIKELENEYYFRNEVFHCMDILTFLSGGDLYNGGRIDMIDNLNIVRDMLVNRMQRISGSNIVIFVKRLGPGTLDFFKQTFGSLPACPEIIPSSIPVSTNGKIVMTPSPFYTVMVKINPTLDNILGILYLYETYHLIDYETIGNQLYLTVSFIDETEYESFLRGEAILQISQCQSINMNYSDDYMMNIYLNFPWLSHDLYDYITRINDDSKSILISLTNEIYASIINRDIIVIYPNFSKAMCNTRDTQQHPIVVLDATNDGLIKKPYRSIPLMKRLTSNEIFIRYGDASLMDMITLSLSKQDISLKRNAEGIRVKHSFSADDIQAIMESDSFLKYSRSKPAAMYQYIFLSFFASGNSIDDILANRDSTLEFSKRTKSKILFGRNTRYDVTAKSSFVCGIVRGKSLDKTSLVEMMWDLKKKGLIYSMEFTNLLSKNTFYLFTFTIYTDEVYDYLNTNKLFSAKCLVVSTKGDVENFSSLKKDVVIRV
What is the function of this protein?
Probably involved in maturation of some viral proteins by processing them preferentially at Ala-Gly-|-Ser/Thr/Lys motifs.  Does not seem to be responsible for the cleavage of major core proteins.
What are the official names of this protein?
Metalloendopeptidase OPG085, Metalloendopeptidase G1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M44 family.
Protein: SYH_LEGPA
Sequence: MVVDKIQAIRGMNDVLPDSTSVWRFIEQTFINCLVRYGYKEIRFPIVENTQLFKRTIGEITDIVEKEMYTFNDLNGDSITLRPEGTAGCVRACIEHGLLHNQQQKLWYLGPMFRHERPQKGRYRQFNQFGVEALGITGTAIELELISICRRLWTDLGFSQSVQLQVNSLGEINERQKYRSILVEYLHDHFHILDEDSKRRLDKNPLRVLDSKNPDLQHLIQNAPKLIDVLGDDSREHFQSFCNGLETLGIPYSINPVLVRGLDYYGQTVFEWVTDQLGSQATICAGGRYDMLVEFLGGAPTPAVGFALGLERIFLLMETLNLLNESNNKQSIFIIATNEEAILKALVMAESIRNAHPSLDVITNTAGGGFKSQFKKADKSGARMALILGEDEIAREYVSIKDLRTEIEQISIPMTKINEFLQNYLA
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_ACIB5
Sequence: MALTNADRAEIIAKFARAENDTGSPEVQVALLTAQINDLQGHFKAHKHDHHSRRGLIRMVNQRRKLLDYLNGKDHERYTALIGALGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: LDH_BACCL
Sequence: MKNNGGTRVVVIGTGFVGASYAFALMNQGIADEIVLIDANESKAIGDAMDFNHGKVFAPKPADIWHGDYDDCRDADLVVICAGANQKPGETRLDLVDKNIAIFRSIVESVMASGFQGLFLVATNPVDILTYATWKFSGLPHERVIGSGTILDTARFRFLLGEYFSVAPQNVHAYIIGEHGDTELPVWSQADIGGVPIRKLVESKGEEAQKELERIFVNVRDAAYQIIEKKGATYYGIAMGLARVTRAILHNENAILTVSAYLDGPYGERDVYIGVPAVINRNGIREVIEIELNDDEKNRFHHSAATLKSVLARFFTR
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: I1BA_CONRA
Sequence: GPSFCKADEKPCEYHADCCNCCLSGICAPSTNWILPGCSTSSFFKI
What is the function of this protein?
Iota-conotoxins bind to voltage-gated sodium channels and act as agonists by shifting the voltage-dependence of activation to more hyperpolarized levels.  This toxin acts on Nav1. 6/SCN8A > Nav1. 2/SCN2A > Nav1. 7/SCN9A sodium channels.  Produces general excitatory symptoms upon intracorporeal injection and repetitive action potentials in the frog cutaneous pectoris muscle.  Natural peptide (with D-Phe) is active on nerve, but not on muscle.  Synthetic peptide (with L-Phe) is not active on both nerve and muscle.
What are the official names of this protein?
Iota-conotoxin RXIA, R11.6, r11a.
What is the protein family that this protein belongs to?
Belongs to the conotoxin I1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ATG8C_ORYSJ
Sequence: MARSSFKLEHPLERRQAEANRIREKYPDRIPVIVEKAERSDIPDIDKKKYLVPADLTVGQFVYVVRKRIKLSAEKAIFIFVKNTLPPTAALMSAIYEENKDEDGFLYMTYSGENTFGLFV
What is the function of this protein?
Ubiquitin-like modifier involved in autophagosomes formation.  May mediate the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton.
What are the official names of this protein?
Autophagy-related protein 8C, Autophagy-related ubiquitin-like modifier ATG8C.
What is the protein family that this protein belongs to?
Belongs to the ATG8 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Vacuole membrane; Lipid-anchor. Cytoplasm, cytoskeleton.
Protein: PSBI_DAUCA
Sequence: MLTLKLFVYTVVIFFVSLFIFGFLSNDPGRNPGREE
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.8 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: Y635_MYCPN
Sequence: MEVDPAEQIEKAGTLITIEGLKKDDYDKAIVNFLALREDLQLLAASPKGDVYRNTSGNGAEIFLNGMKIATDEDFLFSYHIKEPNKKLQRSLNRENKNLPRDCYRENIITILKSNINNRTQTLIDELIDSRDQYDNGEWSFIDVKKLIGLNTNRNILWADSSSKNIEKLIYSLYGMDTKKYEILALNSLQYRSMENDDRLKKQTLMHVSEKLKQQRIEEEAEKIKVKEQKPRKRFEEEDLPIEDLNPIEREGWDWAMEKARELCGFIRGWEKLYEEYQFVLMEKNHKYVGLCYTDQKIIKLSRGILKDEYSLLNTLVHEICHATTNGRDGTKKFERGLTDAFHPLFKLGQSK
What are the official names of this protein?
Uncharacterized protein MPN_635.
What is the protein family that this protein belongs to?
To M.pneumoniae MPN_633 (in the N-terminal section), and M.pneumoniae MPN_634 (in the C-terminal section).
Protein: QUEA_PSEA6
Sequence: MKVSEFQFDLPEALIARYPTKERTASRLMHLATTGLSHLQFTDVVNLINPGDLLIFNNTRVIPARLLGQKASGGKVEVLIERIIDEHHVLAHVRASKSPKEGTQLLLEGKVEMEMVGRQDALFTLKLLNPEPILEILEQYGHMPLPPYIDRPDEESDKERYQTVYNEKPGAVAAPTAGLHFDDVILKQLRDKGVNTEFVTLHVGAGTFQPVRVDNILEHQMHSEYAEVPQNVVDAIAKTKTAGKRVIAVGTTSVRSLESAAKAALENGTALASFFSDTDIFIYPGYKFQVIDAMLTNFHLSESTLIMLVSAFAGKENVMNAYQEAIAQQYRFFSYGDAMFIEKNQD
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNZ_STRGG
Sequence: MSVRELVVLGTASQVPTRHRNHNGYLLRWDGEGILFDPGEGTQRQMLRAGVAAHDIHRICVTHFHGDHSLGLAGVIQRINLDQVPHPVTAHYPASGQHFFERLRYATAYRETVELNQAPVAGAGGVLAATPAYTLDSAKLSHPVESYGYRLTEPDTRRMLPALLREHGIAGPDVGRLQRDGVLGGVTLEQVSEERRGQRFAFVMDTRLCDGVYALAEGSDMLVIESTFLDEDEKLAVDHGHLTAGQAARVARESGVRHLVLTHFSQRYGDPEIFETQARAAGFDGELTVAQDLIRVPVPTRHHP
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: GATC_STRGG
Sequence: MPGITREEVAHLARLARLELKGEELDHFAGQLDDIIGAVARVSEVADQDVPPTSHPLPLTNVMRADEVRPSLTPAQALSGAPAQEQQRFKVPQILGED
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: RNFC_ERWT9
Sequence: MLNLLNLFKKDRLWDFDGGIHPPEMKTQSNGTPLRHLPLPAQFVLPLKQHIGHEGEIGVRPGDQVLRGQPLTFGTGRMLPVHAPTSGTVSKIAPHMTAHPSALAEMCLFILPDGEDRWCEKRPLEDYRSVERSELVARVHQAGVAGLGGAGFPTASKLKGGLHGVNTLIINAAECEPYITADDRLMQDHAAEVLEGSRILAWILQAERVLIGIEDNKPEAIAALKKALGSATDLHIRVIPTKYPSGGAKQLTKILTGKEVPHGGRSTDIGVLMQNVGTAFAVKRAIIDGEPLTERVVTLTGESVAQPGNVWARLGTPISHLLQHAGFIPGAEQMVVMGGPLMGFTLPTLDVPVVKITNCILAPAASEMGQNEAEQGCIRCSACADACPAALLPQQLYWYSRGGDHDKARAHNIADCIECGACAYVCPSNIPLVQYYRQEKAEIQAIDLEAERAALAKNRFEARQQRLEREKAARSAKHQQAKRSVASSDAGAIAAARERVAARQAEGVSPENHADNSLQAAVQAQHEAEVRVHQADLQAANEPVTRQTLDPRKAAVEAAIARTKAKKAAQAAEASPTEAPQQSAPEDEPRKAAVAAAVARTKAKKAAQAAEASPTEAPQQSAPEDVPRKAAVAAAVARAKAKKAAQAAEASATEAPQQSAPEHDPRKAAVAAAVARAKAKKAAQAAEASATEAPLQPAPEDDPRKAAVAAAVARAKAKKAAQAAEASATEAPLQPAPEDDPRKAAVAAAVARAKAKKAAQAAEASATEAPLQPAPEDDPRKAAIAAAIARAKARKTQQPSMQED
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit C, Rnf electron transport complex subunit C.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SAHH_MYCS2
Sequence: MTELKADVRNGIDYKVADLSLADFGRKEIRLAEHEMPGLMALRREYHDVQPLKGARISGSLHMTVQTAVLIETLVSLGAEVRWASCNIFSTQDHAAAAVVVGPNGTPEEPKGVSVFAWKGETLEEYWWAAEQMLTWDGEPANMILDDGGDATMMVLRGAQYEKAGVVPPAEDDDPAEWKVFLGVLRERFEQDKTKWTKIAESVKGVTEETTTGVLRLYQFAAAGELAFPAINVNDSVTKSKFDNKYGTRHSLIDGINRGTDVLIGGKKVLICGYGDVGKGCAESLAGQGARVSVTEIDPINALQALMDGFDVRTVEEAIGEADIVITATGNKDIITLDHMKAMKNQAILGNIGHFDNEIDMAALERSGAKKINIKPQVDQWIFDDGKSIIVLSEGRLLNLGNATGHPSFVMSNSFSNQVIAQIELWTKNDEYDNEVYRLAKHLDEKVARIHVEALGGTLTKLSKDQAEYIGVDVEGPYKPEHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASNA_ENTH1
Sequence: MSLNPPNNLEHIITSQTLKWVFVGGKGGVGKTTTSCSLGVLIADRNPQKKVLIISTDPAHNTSDAFDIKFGAEPKVVPGVPNLSVMEIDVKDAMKGVFDESEQGTNQNGGFGLLSELTGMMGMLKSVPGIDEAIAFSQIINQAQQMNYDLVLFDTAPTGHTLRFLSLPTLLRDMLEKVIKLQDSFGPMMSQFGGMMGMNINFNELKPKMEHMLKTSEQIVEDFTNPNLTTFIPVLIPEFLPLYETERLIQELMNLNMDANSIIVNQILPVNDCCDYCKNKRAIQAKYLGQIDVLYGDFHLIKINMQTNEVRGVAALRAFSKNFEAKH
What is the function of this protein?
ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion.  This process is regulated by ATP binding and hydrolysis.  ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins.  ATP hydrolysis is required for insertion.  Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
What are the official names of this protein?
ATPase ASNA1 homolog, Arsenical pump-driving ATPase homolog, Arsenite-stimulated ATPase.
What is the protein family that this protein belongs to?
Belongs to the arsA ATPase family.
Protein: RPOC_OLEA2
Sequence: MTLDDLFSMRGTAAGQTNIRNLKAMQISIASPESIREWSYGEVKKPETINYRTFKPERDGLFCAKIFGPVKDYECNCGKYKRMKHRGIVCEKCGVEVIASKVRRERMGHIELAAPVAHIWFLKTLPSKIGTLLDMTMADLEKVLYFDSYIVLDPGSTSLAKLQVISEDQYLQIIDHYGEDALVVGMGAEAIRSLLEELNLEALRAELREESQSTRSQTKKKKLTKRLKIVEAFLESDNKPEWMVMEVVPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLMELGAPDIIIRNEKRMLQESVDALFDNGRRGRAITGTNGRPLKSLSDMIKGKQGRFRQNLLGKRVDYSGRSVIVVGPKLKLHQCGLPKKMALELFKPFIYSKLEERGLASTIKSAKKMVEREELVVWDILEEVVREYPILLNRAPTLHRLGIQAFEPLLVEGKAIQLHPLVCAAYNADFDGDQMAVHVPLSVEAQIECRVLMMSTNNILSPANGTPVIVPSQDIVLGLYYMTVERSFEKGEGMAFCAPWEVVAAYDAGSISLHARIKVRMPDGRLLNTTPGRIMVGEVLPEGVHFDLVNTVLTKKNIARLVGNAYRDAGTKATVLLCDRLKDIGYEFATRAGVTIGVKDMTIPQSKKGILADSQAEVDNIERQYRDGIITRTEKYNKVVDVWTKATQDISQEMIKEISYDVMRDEKTGKEELNQSFNPIFMMSNSGARGNQDQMRQLAGMRGLMAKPSGEIIETPITSCFREGLSVLQYFTSTHGARKGLADTALKTANSGYLTRRLVDVVQDVIISEHDCGTVDGLEVGHLIKGGDIKMRLAERVLGRVTLYPVTDPETTEVLFPANTLIDENVAKKLDEAGINSLHIRSALTCRSDRGVCAMCYGRDLARGHVVNIGETVGIIAAQSIGEPGTQLTMRTFHIGGTASREIERSNIQAQYTGRAVLYRVKSVRNKDGQHMVMGKSGQVGIVDEQGREREKYVLPSGAKLHVEEGQEVKKGQLLAEWDPFNEPFVSEVDGLVKFTDIIEGKTVQEKADEATQMTTQTIIEYRTTNFRPAVALCDADGVVKTRPESNIPASYSLPVGAILMVRDGQEITAGDIIARKPRESSKTKDIVGGLPRVAELFEVRKPKDMAVVSQIDGIVTFAGETKGKRKLVVTPETGDEKEYLVPKGKHITVTDGDFVEAGEMLTEGHPELHDILGVKGEKYLANYLVEEIQDVYRFQGVGIDDKHIEVIVRQMLKKVTVLDPGQTSFLVGEQVDKAEFRIENQKAIEEGRTPATAEPLVLGITQASLTTSSFISAASFQETTKVLTEASLRGKNDHLRGLKENVIVGRLIPAGTGYREYVHSDISVPEQKERPDRFLEELVGAPQPVVED
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: DNAJ_SODGM
Sequence: MAKSDYYEILGVSRDAEEREIKKAYKRQAMKFHPDRNRGNAEAEAKFKEIKEAYEVLTDAQKRAAYDQYGHAAFEQGGMGGGGASGADFSDIFGDVFGDIFGGGRRQRVSRGADLRYNMELSLEEAVRGVTREIRIPTLEECDVCHGSGAKPGTSAVTCPTCHGQGQVQMRQGFFAIQQTCPTCQGQGKIIKDPCTKCHGHGRVEKSKTLSVKIPAGVDTGDRIRLSGEGEVGEHGAAAGDLYVQVQVCKHPIFEREENNLYCEVPINFAMAALGGEIEVPTLDGRVKLKVPAETQTGKLFRMRGKGVKSVRGGSQGDLLCRVVVETPVKLNERQKQLLRELEESFGGPSGDQNSPRSKSFLDGVKKFFDDLTR
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ROP_ECOLX
Sequence: MTKQEKTALNMARFIRSQTLTLLEKLNELDADEQADICESLHDHADELYRSCLARFGDDGENL
What is the function of this protein?
Regulates plasmid DNA replication by modulating the initiation of transcription of the primer RNA precursor.  Processing of the precursor of the primer, RNAII, is inhibited by hydrogen bonding of RNAII to its complementary sequence in RNAI.  ROP increases the affinity of RNAI for RNAII and thus decreases the rate of replication initiation events.
What are the official names of this protein?
Regulatory protein rop, RNA one modulator, ROM.
Protein: Y364_MYCPN
Sequence: MELPLDNVDLSKLSPNFLKFNERISGVAKKANYAIPVSLSTEVLALNGPVLHYILNSAKGGNETAVTQRTASTNQQNTLQNSLKINESDPITKELWEKIQKAAETNGKAKEQGKSKKQGTEKTTTLTLLKTESSQQSNTTKDGKATSDEAIKKTWGDYQKVENGLKGYTFKASVFENWHELLDFSARIARSFTNIHTKETKKGTDIQGVLGIDSTPNALFTSVFAAGGGNYDNFFYKVQDGRADFSNFKNKETSYQNLQKVFSDYKELIDKNGLFVNKGGSYSSNFQKFHQLAYSISSTSGFFYSFAGNSAKRLKFDDGNFIEFPRFTQPVKAPNKTTQSGGENNNKSENNLLGTFEIEDKSKKRESVESSEKSSSGTQSKSKKGKSMKTIYLYKAQIPEGKNKGDNAILITNQTVIDKLEKAAKEDGKSGTQVSTIASKSTTKENQENKIIGYTSTDNLREDNKNIFDIDDLNDEKYDRKIIVSATEEVLEQSNTLQSEEAVVLPAPAKYKASDSTKIAITQEPNLIGIHANEKENEETRKFVNWFLNSEQTWESKKYSKNKQNSNEKRTPAQFFADSASYILPLKKTFDNANKKEDQSKANNKTNSQRTNTYIEKALEIFKGISQNQITSYSDPSDFRSGRFRDGIGSNFNAVVNSKVDFNKFINNFIASLGSDI
What are the official names of this protein?
Uncharacterized protein MPN_364.
What is the protein family that this protein belongs to?
Belongs to the MG185/MG260 family.
Protein: RBSD_CLOTE
Sequence: MKKIGILNNEISHVISKMGHTDSLAIGDCGLPIPEETKRIDLALIKNIPTFMDTLKSVMMELQVEEVQIANETQDLSSELFKEIKKQLGHAKITFISHEELKNNLKHCKAVIRTGEQTPYANIILKSGVVF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPA_BACAN
Sequence: MKKKHRIKKNDEFQTVFQKGKSNANRQFVVYQLDKEEQPNFRIGLSVSKKIGNAVVRNRIKRMIRQSITELKDEIDSGKDFVIIARKPCAEMTYEELKKSLIHVFKRSGMKRIKSSVRK
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: LSRB_YERPP
Sequence: MRTQRLKKLALVCALGFACITTAQAAERIAFIPKLVGVGFFTSGGKGAVDAGKALGVDVTYDGPTEPSVSGQVQLINNFVNQGYNAIVVSAVSPDGLCPALKRAMQRGVKILTWDSDTKPECRSVYINQGTPNQLGSMLVDMAANQVKKEQAKVAFFYSSPTVTDQNQWVNEAKKKIQQEHPGWEIVTTQFGYNDATKSLQTAEGILKAYADLDAIIAPDANALPAAAQAAENLKRANVAIVGFSTPNVMRPYVERGTVKEFGLWDVVNQGKISVYVANEMLKKGDLNVGDKIDIPNIGVVEVSPNRVQGYDYEAKGNGIVLLPQRVIFTKENISKYDF
What is the function of this protein?
Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import.  Binds AI-2 and delivers it to the LsrC and LsrD permeases (By similarity).
What are the official names of this protein?
Autoinducer 2-binding protein LsrB, AI-2-binding protein LsrB.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 2 family.
What are the subcellular locations of this protein?
Periplasm.