PharMolix/UniProtQA huggingface dataset:
Protein: LEXA_BURTA
Sequence: MIKLTARQQQVFDLIRRAIERSGFPPTRAEIAAELGFSSPNAAEEHLRALARKGVIELAAGASRGIRLLGLDDAPHQLTLPHAALMQLSLPLVGRVAAGSPILAQEHISQHYACDPALFSSKPDYLLKVRGLSMRDAGILDGDLLAVQKRAEAKDGQIIVARLGDDVTVKRLKRRPGGVELIAENPDYENIFVKAGSAEFALEGIAVGLIRPGEF
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: MNMG_TREDE
Sequence: MYRFSDYDVIVVGAGHAGIEAALASARMGEAVLLITQTLDSAGRLSCNPSIGGISKGNIVREIDALGGEMGKLADASMIQYRLLNKSRGPAVQAPRVQADKFLYSQLAKHAIELEKNLHVFQDTVIDIVSSNTNESGYVEKGSVQYVKTERGREFSAKAVVLATGTFMEGKIYIGEYESPDGRLGERAAIGLGPALAKKGFTVGRLKTGTPMRILRRSFDSSLTEEQEADEIMRPFSFSNAEIHRPYAKCYITHTNQETHDIIRENLHRAALFSGKITGTGARYCPSIEDKIKKFPERDRHHVYIEPEGLNTEELYINGLSSSLPEDVQDRMIRTIPCFKDVIITRPAYAVDYAYVSPIQLSSDLQTRRIEGLFLAGQINGTSGYEEAGGQGIIAGINAALFSRSLKFKDEKYVPFVLKRDEAYIGVMIDDLVTQGVDEPYRMFTARAEYRLNLRHDTADERLTERAYQIGLQTKEASNRLKEKLLTREKIISLWKDIKITRDLIAKNPELKNHIGKSLADALHDPQVSLECICAIDENSKDYSAELLESAELEIRYEHYIAVQNRKIAKVKRMENTKIPADFDYDAVSGLSTESRTRLKEVRPETIGQASRIRGIRPSDIMLLSILL
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_VIBCM
Sequence: MELMVKGANALTVSETTFGREFNEALVHQVVVAYAAGARQGTRAQKTRSEVSGGGAKPWRQKGTGRARAGTIRSPIWRTGGVTFAAKPQDHSQKVNKKMYRGAMKSILSELVRQERLIVVENFSVEAPKTKALVAKLKELELNDVLIVTGEVDENLFLAARNLYKVDVRDVTGIDPVSLIAFDKVLMTAAAVKQVEEMLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: SDHE_SALPA
Sequence: MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRNRERGPVAI
What is the function of this protein?
An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins.  Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
What are the official names of this protein?
FAD assembly factor SdhE.
What is the protein family that this protein belongs to?
Belongs to the SdhE FAD assembly factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNPEP_SCHPO
Sequence: MTATAKSCALDFLDFVNASPTPYHAVQNLAEHYMSHGFQYLSEKSDWQSKIEPGNSYFVTRNKSSIIAFSIGKKWKPGNGFSIIATHTDSPTLRLKPKSQKSAYGYLQVGVEKYGGGIWHTWFDRDLSLAGRVMVEEEDGRVIQYNVHIDRPLLRIPTLAIHLDPSANSSFSFNMETEFVPLIGLENELAKEETSDNGDKYHHPVLLSLLANEISKSLETTIDPSKIVDFELILGDAEKARLGGIHEEFVFSPRLDNLGMTFCASQALTKSLENNSLDNESCVRVVPSFDHEEIGSVSAQGAESTFLPAVLQRICELGKESSLFSISMVKSFLVSADMAHAMHPNYSSRYENSNTPFLNKGTVIKVNANQRYTTNSAGIVLLKKVAQLADVPIQSFVVRNDSPCGSTIGPKLAAMTGMRTLDLGNPMLSMHSCREMCGSKDFEYAVVLFSSFFQNFANLEEKIIIDE
What is the function of this protein?
Aspartyl aminopeptidase that is able to remove aspartyl residue at N-terminus of angiotensin I.  Acts also as a chaperone and efficiently suppressed the thermal aggregation of citrate synthase.
What are the official names of this protein?
Aspartyl aminopeptidase 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M18 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEXA_ACTP7
Sequence: MSRKHLTARQQEIFDFVKHHIETTGMPPTRVEIAREIGFKSPNAAEEHLKALARKGYIEMLSGTSRGIRILVDNEETAANDDGLPLIGKVAAGTPIMAIEHVESHYPVNGAMFNPNADYLLKVNGNSMEKIGILDGDLLAVHKTNFARNGQVVVARVDDEVTVKRLEKKGDLIYLHPENDELQPIVVDPRIEYIEIEGIAVGVIRNNAWM
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: CRR1_YEAST
Sequence: MRISILQLVPVVGYIGFALGELYKPKNSISCSPNNPCPAEWPCCSPYNECGAGPICVGGCNVRSSFDEESCAPIPALVASQKLEFVSTPKVPKFIVNYQPKPPIREGNGPNKANTKVGVVEGELNSKRIIHYAKFLVTPDSKEAEKMLEDFDFTHSGYTSIEASSGNIVLAMPKKTTGSLITSTRSFLYGKASVRMKTARSRGVVTAFDLTSAIGDEIDFEWLGGDLMTAQSNYYSQGHLDYTRMQRFPVGADTWATYHTYEIDWDPDRIIWYVDGKIARTVLKKDTWDPISKEYRYPQTPMRLEIAVWPGGSETNGPGTINWAGGLIDWENSPDIIEKGQFTAHVEQITVTPYQNKFTEQVQFCIKAKKKAPTFSQKDLSRVVVSYNRQDRLNHHDEGSLKWDCFVTPKINDWLSSWKRSK
What is the function of this protein?
Spore specific glycosidase involved in spore wall assembly during sporulation.  May be involved in copper import.
What are the official names of this protein?
Probable glycosidase CRR1, CRH-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 16 family. CRR1 subfamily.
What are the subcellular locations of this protein?
Spore wall. Note=Spore wall envelope.
Protein: HISZ_GLUOX
Sequence: MSLYSETPSAALLPSGFADLLPGEAEAEARGIASVMEAFSRHGYQRVRPPLLEFETSLLGGSGESLAPQTFRLMDPNSHRMMALRPDMTTQIARIASIRLQDAPRPLRLSYSGSCIVVGTPGREADRQISQAGIELIGPDSAQADAEVIALGAKALAELGIEGVSFDLSMPALALGLIEGVIPEADREPLLHALDRKDASAVAELGGPIAGMLAVMLRAAGPADRALDLLASLDYPKDVVGYFERLAASVAAIRERSPDLRLTIDPVDFRGWRYHTGLCVTVFSTSSREELGRGGRYLAGQEPACGLTLRPQALLRAAPVSASRPRCYVPVDLDAASLSGLHKAGYATVSALSHDEDAAAQARHLRCTHVWKDGAARPL
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOB_ALKMQ
Sequence: MINRVVLFIMDSVGIGALPDADQFGDVGSNTLGNISKVEQGIALPNLTALGLGNIEDIQGVNPVESPKGAYGKSAEVSNGKDTTTGHWELVGLEVTEPFNTYPQGFPADVVENFEKQIGRKMLGNKPASGTVILDELGKEHMQTGHPIVYTSADSVFQIAAHEEVILLGELYKMCEIAREIMRGDHAVARVIARPFVGDPGNFIRTSNRRDYSLDPFGKTLLDIAKEAGKDVIGIGKIEDIFNGNGITEAIHTKDNMDGIDQTIAYLKKENKGIIFTNLVDFDSKYGHRRDPKGYKQALEEMDRRIPEILSHLNDEDLIIFTADHGNDPTFKGSDHTREYIPIVIYGKQVKAGVNIGTRKSFADIAATISDILNIDDTGNGESFKKFILE
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_STRPG
Sequence: MRIADYSVTKAVLDRHGFTFKKSFGQNFLTDTNILQKIVDTAEIDQNVNVIEIGPGIGALTEFLAENAAEVMAFEIDDRLVPILADTLRDFDNVQVVNQDILKADLQTQIKQFKNPDLPIKVVANLPYYITTPILMHLIESKIPFQEFVVMMQREVADRISAEPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRDQPLIEIKDEDFFFRVSRLSFVHRRKTLWNNLTSHFGKSEDIKTKLEKGLALADIKPSIRGEALSIQDFGKLADALKEVGL
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y454_BACMK
Sequence: MGIKYSNKINKIRTFALSLVFIGLFIAYLGVFFRENIIIMTTFMMVGFLAVIASTVVYFWIGMLSTKTIQIICPSCDKPTKMLGRVDACMHCNQPLTLDRNLEGKEFDEKYNKKSYKS
What are the official names of this protein?
UPF0295 protein BcerKBAB4_0454.
What is the protein family that this protein belongs to?
Belongs to the UPF0295 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: INS_PANBU
Sequence: MALWLQAFTLLVLLVLSSPGAQSASSQHLCGSHLVDALYMVCGEKGFFYQPKTKRDVDPLLGFLSPKSAQENEADEYPYKDQGDLKVKRGIVEQCCHHPCNIFDLQNYCN
What is the function of this protein?
Insulin decreases blood glucose concentration.  It increases cell permeability to monosaccharides, amino acids and fatty acids.  It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
What are the official names of this protein?
Insulin.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: LEUD_BURP6
Sequence: MEKFNVHTGVVAPLDRENVDTDAIIPKQFLKSIKRTGFGPNAFDEWRYLDHGEPGQDNSKRPLNPDFVLNQPRYQGASVLLARKNFGCGSSREHAPWALQQYGFRAIVAPSFADIFFNNCYKNGLLPIVLTEQQVDHLFNDTYAFNGYQLTIDLDAQVVRAPDGREYPFEITAFRKYCLLNGFDDIGLTLRHADKIRQFEAERLAKQPWLDNRLVG
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: GFPT2_RAT
Sequence: MCGIFAYMNYRVPKTRKEIFETLIRGLQRLEYRGYDSAGVAIDGNNHEVKERHIHLVKKKGKVKALDEELYKQDSMDLKVEFETHFGIAHTRWATHGVPNVVNSHPQRSDKDNEFVVIHNGIITNYKDLRKFLESKGYEFESETDTETIAKLIKYVFDNRETEDITFSTLVERVIQQLEGAFALVFKSIHYPGEAVATRRGSPLLIGVRSKYKLSTEQIPVLYRTCTIENVKNICKTRLKRLDSSTCLHAVGDKAVEFFFASDASAIIEHTNRVIFLEDDDIAAVADGKLSIHRVKRSASDDPSRAIQTLQMELQQIMKGNFSAFMQKEIFEQPESVFNTMRGRVNFETNTVLLGGLKDHLKEIRRCRRLIVIGCGTSYHAAVATRQVLEELTELPVMVELASDFLDRNTPVFRDDVCFFISQSGETADTLLALRYCKDRGALTVGITNTVGSSISRETDCGVHINAGPEIGVASTKAYTSQFISLVMFGLMMSEDRISLQTRRQEIIRGLRSLPELIKEVLSLDEKIHDLALELYTQRSLLVMGRGYNYATCLEGALKIKEITYMHSEGILAGELKHGPLALVDKQMPVIMVIMKDPCFAKCQNALQQVTARQGRPIILCSKDDTESSKFAYKTIELPHTVDCLQGILSVIPLQLLSFHLAVLRGYDVDFPRNLAKSVTVE
What is the function of this protein?
Controls the flux of glucose into the hexosamine pathway.  Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2, D-fructose-6-phosphate amidotransferase 2, Glutamine:fructose-6-phosphate amidotransferase 2, GFAT 2, GFAT2, Hexosephosphate aminotransferase 2.
Protein: SHARK_DROME
Sequence: MSRDSDPMKWYHGNLSREAADELLKQGYEDGTFLVRESSTAAGDFVLSLLCQGEVCHYQVRRHGGEDAFFSIDDKVQTKILHGLDTLVDYYQQAANGLPTKLTVPLIRDLPPHNTRSHGVTNLLHRATSKNESKVVFELLKCGYRNFDAKNQDGQTALHLAALHSDEDILKHLLNAKVQVNSSDSFGCQPLHYAARSKPASFIRTLISAQANVQGRNIDNGYVPLHEAAKHGNLEAVQELLLAEAPPLPRTSSGEFPFDLAKEAGQTAVEEFLLNYKLPPANTTRDQWYHGTLTREEAVAILKKHAKELLAKQPEVDTSGCFLVRYSESPAASGLVLTLLCDQVVKNFRISQADLYQNGNKVQSGGSKFLYIDDGPYWPSVEHLIAHFMRFSYGLPVSLKYPVPPQPKPEVPSFATIPRSNMKPKAASPATPPTPVSPHSHHQHPHVPALTITKKKQKENSSSMFNTLRLTSPKKALFDMNSLRKNKSKGKRSDSESSVSGSLAGTEQELQAAAPMLKSLSFSTEFSTFNADGVTGSGAAAAGEVYNVPRNNTPIEIDLPPIAQKTEAEVEYFTKSDVAIERERAGQWIGNGYQPTMDVLSLLDQQIKAPAVARLNSLGPNASTESEMASYLHRKCSGTPSTPSATEVEAAKLRFFIEPEKLVLDREIGHGEFGSVHSGWLLRKSGAGEESRLEVAIKMLSDEHSNKQEFLREASVMMRLEHKCIVRLIGIAKGEMLMMVQELAPLGSMLQYILDHGHEITANAELKVWASQIACGMHYLESQHFVHRDLAARNILLTARHQAKISDFGMSRSLRPGSTEYQFTQGGRWPIRWYAPESFNLGIFSHASDVWSFGVTIWEMFSLGAPPYGEISNVDAIKLVDSGERLPQPNLCPAYIYAVMQSCWKERPKDRPTFVYLTEFFARDPDYQNLPELVQTVHI
What is the function of this protein?
Following axon injury, required for recruitment of drpr and glial cells to severed axons and for glial clearance of severed axons from the central nervous system (PubMed:18432193).  Together with Src42a and drpr, promotes the migration of macrophages to sites of wounding as part of a signaling cascade where Scr42a detects production of hydrogen peroxide at wound sites which triggers phosphorylation of drpr and subsequent recruitment and activation of shark (PubMed:26028435).  May be involved in signal transduction on the apical surface of ectodermal epithelial cells, regulating their polarity during invagination (PubMed:7892198).  Crumbs (crb) may be the intracellular signal (PubMed:7892198).
What are the official names of this protein?
Tyrosine-protein kinase Shark.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Apical expression in cephalic furrow and tracheal cells. Limited to luminal surface and absent from the basal surface.
Protein: RPOA_CAMFF
Sequence: MKKITTSAYMPTEIEVVNVSENVAKIIAYPFETGYAVTLAHPLRRLLYTSTVGFAPTAVKIDGVAHEFDSMRGMLEDVTLFIINLKNLRFKLKNDSKREVIEYSFKGPKEITGIDLNNDIVEIVNPDSYLATINEDAELKFSLIVEKGIGYVPSEEIRDYIDSEYIALDAFFTPVKKAVYEIENVLVEDNPDYEKIVLTVTTDGQVSPIEAFKHSIEAMYKQMSIFNNVLNIDVNMALTSSQNSNEHSKLLESVENLNLSARSFNCLDKADIRYIGELALMEESELKDLKNLGKKSLDEIKAVMAEIGYPFGENTLGDSKEALRKKISELKS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: TRI69_MOUSE
Sequence: MEVSSRPPSNFDPGNYVEMSDPTTTHLPSKVVIQDLTTELHCPLCNDWFRDPLMLTCGHNFCQDCIQSFWKVHSKETFCPDCKMLCQYSNCTFNLVLEKLVEKIKKLPLLKGHPQCPEHGENLKLFSKPEGKMICFQCKDARLSMGQSKDFLQISEAVRFFTEELAIYQSQLQTTLKELQSLRTIQKDAISAYKDNKIQLQQNLSLEFLKLHQFLHNKEKDILNDLRDEGKLLNEEMEVNLNQIQEQCLVAKDMLATIQARMEQQNSFDFLTDITKLIESMEKGMKTIVPRQLIAKKLSLGRFKGPIQYIIWKEMQAILSPGPSQLTLDPKTAHPNLVLSKSQTSVCHCDVKQVMPDDPERFDSSVAVLGSKGFTSGKWYWEIEVGKKTKWTIGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSRSLTLGDLRRVGVYLDYEGGQVSFYNATTMTHLYTFSSVFQEKLFPYLCPCLNDGGENKEPLHIVHPQ
What is the function of this protein?
E3 ubiquitin ligase that plays an important role in antiviral immunity by restricting different viral infections including dengue virus or vesicular stomatitis indiana virus.  Ubiquitinates viral proteins such as dengue virus NS3 thereby limiting infection.  In addition, acts as a key mediator of type I interferon induced microtubule stabilization by directly associating to microtubules independently of its E3 ligase activity.  Plays also a role in cataract formation together with TP53.  Mechanistically, inhibits UVB-induced cell apoptosis and reactive oxygen species (ROS) production by inducing TP53 ubiquitination.
What are the official names of this protein?
E3 ubiquitin-protein ligase TRIM69, RING finger B-box coiled-coil transcription factor, RING finger protein 36, RING-type E3 ubiquitin transferase TRIM69, Testis-specific RING finger protein, Tripartite motif-containing protein 69.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus speckle.
Protein: PCEB_DESHY
Sequence: MNIYDVLIWMALGMTALLIQYGIWRYLKGKGKDTIPLQICGFLANFFFIFALAWGYSSFSEREYQAIGMGFIFFGGTALIPAIITYRLANHPAKKIRESSDSISA
What is the function of this protein?
May act as a membrane anchor for the tetrachloroethene reductive dehalogenase PceA.
What are the official names of this protein?
Probable tetrachloroethene reductive dehalogenase membrane anchor protein.
What is the protein family that this protein belongs to?
Belongs to the PceB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL5_BUCAP
Sequence: MTTFYDYYKSKIVKKLMMELNYSSIMQVPKIDKITLNMGVGAASSDKKVLDNAVLDLTAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGKRKWDFFERLIVIAIPRIRDFRGLSTNSFDGKGNYSLGIREQIIFPEIDYDKIDRVRGLDITITTTANSDHEARLLLSSFNFPFRK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: CIF1_SCHPO
Sequence: MSEEIITESIVKNFGSAETSVGEKQPKRKRSEVRAEKLKARKLQKAAEIVQKQKENRKILKDVSLKRLSKSLDRSLPSENTIDQISFNHAMSEEDASGYQIGDKHKNLLLYKLSSSSGSVFTENLYSTIQEFLSAQKVDIADSKNTYVFGSTFDKKSHALVKTSDSVRSLKYGSFVKACAPLFRFASGIIKAHAPHFHQALLKLELAPSALRFGVFPNFSLQSVSNGYMSMESNFSSIKYGFVVIIIVGELNDVELKIPAISHSLKLKDGSILVLRSSLLHQWYSLPKQSILYEIRLFAMSSLWHYEKNKSIKIAKKDDI
What is the function of this protein?
Induces a stably inheritable state of calnexin independence called the Cin state when overexpressed.
What are the official names of this protein?
Calnexin-independence factor 1.
Protein: METK_TERTT
Sequence: MSEYSIFTSESVSEGHPDKMADQISDAVLDAILKDDKHARVAVETLVKTGMAIVAGEVRTSTYVDLEDLIRQVILDIGYNSSDVGFDGASCAVINAIGKQSADIAMGVDEAENKDMGAGDQGLMFGYATNETDVLMPAPIYYSHRLVEKQAELRKSGAHAWSRPDAKSQVTLRYENGKPVAVDAVVLSTQHAPGVSQAQIHEAVMEEIIKPVLPAEWLHSNTKYHINPTGQFIIGGPVGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLADRCEIQVSYAIGVAEPTSISVNTFGTGKIDDGKIVELVKEHFDLRPRGLIEMLDLMRPIYRKTAAYGHFGRELPEFTWEITDKADVLKAAL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2259_MYCBO
Sequence: MPRLAFLLRPGWLALALVVVAFTYLCFTVLAPWQLGKNAKTSRENQQIRYSLDTPPVPLKTLLPQQDSSAPDAQWRRVTATGQYLPDVQVLARLRVVEGDQAFEVLAPFVVDGGPTVLVDRGYVRPQVGSHVPPIPRLPVQTVTITARLRDSEPSVAGKDPFVRDGFQQVYSINTGQVAALTGVQLAGSYLQLIEDQPGGLGVLGVPHLDPGPFLSYGIQWISFGILAPIGLGYFAYAEIRARRREKAGSPPPDKPMTVEQKLADRYGRRR
What are the official names of this protein?
Uncharacterized SURF1-like protein Mb2259.
What is the protein family that this protein belongs to?
Belongs to the SURF1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FOLD_LACAC
Sequence: MGKILDGKFVANLLGEKLKEKVKDLKEEGITPHFCVINIGDDPASKIYVRTKKRRAEKMGIIQDIYQLPADTKQEVALNLIDKLNEDPDINGVMVQLPAPEQIDADELLERIDPNKDVDGLTPSNIGRIWMENHFIEPATAEGIIALLKYYKILLKGKNVVVIGRSNIVGKPVAALMLEQNATVTIAHSETENLAELTRNADIIVSATGQAFLVTEDMVKDGVVVVDVGMNHVNGKLVGDVDFENVKKKASYITPVPGGVGPLTVQFLMEAVVKLTRRQNGRE
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: CSM3_PHANO
Sequence: MAPSRANTPSDDELDNILNGITEGRDISGTQAESTRPAYASKGSGNAGDGLGIDEEIIITKKRIPIPKLDDNRLLSDPGIPRLRRISKDRLRFKGKGHEYGDIARMLNMYQLWLDDLYPRAKFADALTIIEKVGHTKRMQMMRKEWIDEGKPRRTSAYEEEDADEVVVQAPTTEQATESMEGVEQGEEGAERAGPDEDELDALLAESAQQNTSAPKTLPVRTAGGEDDPFADEMEAMVDMEDMW
What is the function of this protein?
Forms a fork protection complex (FPC) with TOF1 and which is required for chromosome segregation during meiosis and DNA damage repair.  FPC coordinates leading and lagging strand synthesis and moves with the replication fork.  FPC stabilizes replication forks in a configuration that is recognized by replication checkpoint sensors (By similarity).
What are the official names of this protein?
Chromosome segregation in meiosis protein 3.
What is the protein family that this protein belongs to?
Belongs to the CSM3 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PCKA_LEPBP
Sequence: MSVSTNLKGLAELGLKPSEVFHNLSYEEIYQHELNNKEGVTSDNGTMMVDTGIFTGRSPKDKYFVDEPSSQNNIWWGPVNTKVSEAIFNELYAEVTKFLDNKKLYVFDGHAGTNDDTRISLRVVTERAWQHHFCTNMFLRPTKEELAKLDPEFTIINASGYKNPKYKEHGLNSEVFVIFHLAKKICIIGGTEYGGEMKKGIFSVMNYYLPLKNVLTMHCSANVGKDGDSALFFGLSGTGKTTLSTDPNRKLIGDDEHGWDDNGIFNIEGGCYAKTINLDPKTEPEIYAAIRRDALLENVVYDATTKKVDYSSAAKTENTRVSYPIFHIDNIQPGSKAGHPNTVIFLTYDAYGVLPAVSKLSIEQAMYHFLSGYTAKVAGTERGVKEPQATFSACFGQAFMTLHPTYYAKLLGEKMKKHQVNAYLINTGLVGGKYGVGKRMNLPATRQIINEILNGNIEKSEFEKHPVFQVSFPKSVNGVDAHILNPRNAWENKEDYDKTAADLAKQFVENYKKYLTGSKEFDYSQYGPIA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLU_ACTP2
Sequence: MSMTPREIVSELDAHIIGQNEAKRAVAIALRNRWRRMQLPEDLRQEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIKDLTDVAVKLVKSQAVEKNRMRAQDAAEDRILDVLLPPAKDQWGNVQESDNSSTRQVFRKKLREGQLDDKEIEIDVAAQVSVEIMTPPGMEEMTSQLQSLFEGMSPNKTKKRKMKIKDALKVMVDEEAAKLVNPEELKQQAIEAVEQHGIVFIDEIDKICKKGEHSGGDVSREGVQRDLLPIIEGSTVNTKHGMVKTDHILFICSGAFQVARPSDLLPELQGRLPIRVELKSLTKEDFERILTEPNASLTLQYRELMKTEGVEIEFTKDGISKIAESAFRVNEKTENIGARRLHTVLERLMDGISFDASERSGEKIVIDEKYVQAALNDVVENEDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSD2_AMAEX
Sequence: MSDINATRLPIIWAPVVPCISDDNDSTLTRGQR
What is the function of this protein?
Probable toxin that belongs to the MSDIN-like toxin family responsible for a large number of food poisoning cases and deaths (PubMed:24050899).
What are the official names of this protein?
MSDIN-like toxin proprotein 2.
What is the protein family that this protein belongs to?
Belongs to the MSDIN fungal toxin family.
Protein: Y377_MYCGE
Sequence: MATNLKSIAKLQKPIQYDKVIEVDRIFADPAFIEQHRQRILASFKDAKESALYHELTHIVIKDNLFSAAMNEIVSYFEFQINPEELKNVVEGLKRDVVKDADEKTIQSIAEKIIKKALVFNFLQKEWKVEVSDDIVKRVISLYYEKTNQNVREYLDDKQKFEGIRTALIEERMVLETINHFKFHFNLTGQLPS
What are the official names of this protein?
Uncharacterized protein MG377.