PharMolix/UniProtQA huggingface dataset:
Protein: LEU1_SHEHH
Sequence: MSNRVIIFDTTLRDGEQALAASLTVKEKLQIALALERLGVDVMEVGFPVSSPGDFESVQTIAKTIKNSRVCALSRALESDIDAAAQALSVAEQFRIHTFISTSTIHVENKLKRSFDQVLDMAVGAVKYARRFTDDVEFSCEDAGRTPIDNLCRMVEEAIKAGARTINIPDTVGYTVPSEFGGIIQTLFNRVPNIDQAVISVHCHDDLGLSVANSITAVQHGARQIECTVNGIGERAGNCSLEEIAMILSTRKGELGLETGINAKEIHRTSSLVSQLCNMPVQANKAIVGANAFTHSSGIHQDGMLKAQNTYEIMTPESIGLNRNNLNMTSRSGRHVIKHRMSELGYGEQDYDMDVLYEEFLALADKKGQVFDYDLEALAFMEAQAEDDDHFELQQLVVHSDSTEGSATATVKVAVNGETITEAATGNGPVDAAYKAVARASGCKTNITSYQLSAKGEGHNALGQVDITAKYREQNFHGVGLATDVVEASAKALIHVMNLTWRADKVADCKQRIQQNKQEFGSV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: BLTD_BACSU
Sequence: MSINIKAVTDDNRAAILDLHVSQNQLSYIESTKVCLEDAKECHYYKPVGLYYEGDLVGFAMYGLFPEYDEDNKNGRVWLDRFFIDERYQGKGLGKKMLKALIQHLAELYKCKRIYLSIFENNIHAIRLYQRFGFQFNGELDFNGEKVMVKEL
What is the function of this protein?
Acetylates both spermidine and spermine at primary propyl amine moieties, with spermine being the preferred substrate.
What are the official names of this protein?
Spermine/spermidine N(1)-acetyltransferase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family.
Protein: NSRR_ECO55
Sequence: MQLTSFTDYGLRALIYMASLPEGRMTSISEVTDVYGVSRNHMVKIINQLSRAGYVTAVRGKNGGIRLGKPASAIRIGDVVRELEPLSLVNCSSEFCHITPACRLKQALSKAVQSFLTELDNYTLADLVEENQPLYKLLLVE
What is the function of this protein?
Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress.  May require iron for activity.
What are the official names of this protein?
HTH-type transcriptional repressor NsrR.
Protein: TAF11_PONAB
Sequence: MDDAHKSPSDKGGETGESDETAAAPGDPGATDTDGIPEDTDGDADADLKEAAAEEGELKSQDISDLTTVEREDSSLLTPAAKKLKIDTKEKKEKKQKVDEDEIQKMQILVSSFSEEQLNRYEMYRRSAFPKAAIKRLIQSITGTSVSQNVVIAMSGISKVFVGEVVEEALDVCEKWGEMPPLQPKHMREAVRRLKSKGQIPNSKHKKIIFF
What is the function of this protein?
The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription.  TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC).  The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13.  TAF11, together with TAF13 and TBP, play key roles during promoter binding by the TFIID and TFIIA transcription factor complexes.
What are the official names of this protein?
Transcription initiation factor TFIID subunit 11, TFIID subunit p30-beta, Transcription initiation factor TFIID 28 kDa subunit, TAF(II)28, TAFII-28, TAFII28.
What is the protein family that this protein belongs to?
Belongs to the TAF11 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRMN6_ECO81
Sequence: MSQSTSVFRRNGFTFKQFFVAHDRCAMKVGTDGILLGAWAPVAGVKRCLDIGAGSGLLALMLAQRTDDSVMIDAVELESEAAAQAQENINQSPWAERINVHTADILQWITQQTVRFDLVISNPPYYQQGVECATPQREQARYTTTLDHPSLLTCAAECITEEGFFCVVLPEQIGNGFTELALSMGWHLRLRTDVAENEARLPHRVLLAFSPQAGECFSDRLVIRGPDQNYSEAYTALTQAFYLFM
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAHH_RHIEC
Sequence: MSTEKDYVVADIGLADFGRKEITIAETEMPGLMSCRAEFGEAKPLKGARITGSLHMTIQTAVLIETLVALGAEVRWASCNIFSTQDHAAAAIAAAGVPVFAIKGESLEDYWVYTDKIFQWADGGLSNMILDDGGDATMYILLGARAEAGEDVLSNPHSEEEEILFAQIKKRLAASPGWFTKQRDAIKGVTEETTTGVNRLYQLSQKGLLPFPAINVNDSVTKSKFDNKYGCKESLVDGIRRGTDVMMAGKVAVVCGYGDVGKGSAASLSGAGARVKVTEADPICALQAAMDGYEVVLLEDVVSSADIFITTTGNKDVIRIDHMRQMKDMAIVGNIGHFDNEIEVAALRNLKWTNVKPQVDLIEFPKGNRIILLSEGRLLNLGNATGHPSFVMSASFTNQTLAQIELFTKPGQYENKVYILPKHLDEKVARLHLDKLGVKLTQLSEEQAAYIGVKPQGPFKSDHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y6510_RICAH
Sequence: MDKFYNYNSSLHQVLLNLKVKPNSKQNLISNFVIINNIPYLKLSIKATPEKGKANEEIINYLAKAWKLSRSNIEIIKGHTHSVKTILIKNINEDYLNFIINSYIR
What are the official names of this protein?
UPF0235 protein A1C_06510.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: RS3A2_DEBHA
Sequence: MAVGKNKRLSKGKKGLKKKVVDPFTKKEWFDIKAPSTFENRAVGKTLINRSTGLKNAADGLKGRVVEVCLADLQGSEDHSSRKVKLRVDEVQGKNLLTNFHGIDFTTDKLRSLVRKWQSLVEANVTVKTSDDYVLRIFAIAFTKRQANQIRKTTYAQSSKLREVRKKMIEIMQREVSNCTLAQLTSKLIPEVIGREIEKSTQTILPLQNIHIRKVKLLKQPKFDLGSLLALHGEGSTEEKGKKVSAGFKDVVLEAV
What are the official names of this protein?
40S ribosomal protein S1-B.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VEA_EMENI
Sequence: MATLAAPPPPLGESGNSNSVSRITREGKKITYKLNIMQQPKRARACGQGSKSHTDRRPVDPPPVIELNIFESDPHDDSNKTDITFVYNANFFLFATLEPERPIATGKLMTNQGSPVLTGVPVAGVAYLDKPNRAGYFIFPDLSVRNEGSYRFSFHLFEQIKDPKDATEGTQPMPSPVPGKLSSPQEFLEFRLEVISNPFIVYSAKKFPGLTTSTPISRMIAEQGCRVRIRRDVRMRRRGDKRTEDYDYDNERGYNNRRPDQYAGSDAYANAPERPRSTSISTNMDPYSYPSRRPSAVEYGQPIAQPYQRPMASTPAPSSTPIPAPIPMPGPVALPPSTPSPASAHAPAPPSVPLAAPPPLHTPSYQSHLSFGATQTQYPAPQLSHIPQQTTTPTHPYSPRSSISHSRNQSISEYEPSMGYPGSQTRLSAERPSYGQPSQTTSLPPLRHSLEPSVNSRSKTPSNMITSLPPIQSLSELPSTTSQPSSAIGSSPANEPGPRLWETNSMLSKRTYEESFGHDDRPLYNGMRPDSESYPGGMQRRPSYERSSLLDGPDQMAYKRANGRMVSKPATMR
What is the function of this protein?
Component of the velvet transcription factor complex that controls sexual/asexual developmental ratio in response to light, promoting sexual development in the darkness while stimulating asexual sporulation under illumination (PubMed:12223191, PubMed:2253875, PubMed:2076818, PubMed:14665453, PubMed:18556559, PubMed:19210625).  The velvet complex acts as a global regulator for secondary metabolite gene expression (PubMed:18556559).  Controls the expression of the sterigmatocystin and penicillin gene clusters (PubMed:14665453, PubMed:17375284).  Represses the cryptic ors gene cluster producing orsellinic acid and its F9775 derivatives in a laeA-independent manner (PubMed:23841751).  Required for full induction of faoA gene expression by fructosyl amines (PubMed:12375102).  Positively regulates the expression of the early sexual development gene esdC (PubMed:17977758).  Controls the expression of mannoprotein mnpA (PubMed:12620259).
What are the official names of this protein?
Developmental and secondary metabolism regulator veA, Velvet complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the velvet family. VeA subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Enriched in the nucleus in the dark (PubMed:17163983, PubMed:18556559, PubMed:20816830). Migration to the nucleus depends on the importin alpha carrier protein KapA (PubMed:17163983, PubMed:19318129). Migration to the nucleus is also controled by llmF (PubMed:23341778).
Protein: COQ4_CANGA
Sequence: MLQSTKVTKSVLTNVLRVEQRRGFLLSGAAVALGSTYIFGRDAKLADAMDRGELHNKNEDYAKLRAERTEQRIKALSNNRPMEPRYEGHVPLYLHEKMLLFAISGIRAFFHPENGINIVQLGEATAFPIFLENLKQTMLADETGRRILRDQPNVRTDILDMDKLSKLPKNTFGYTFYKWLEKEKVSPDTRAPVTYIDDPIHAFVFKRYRQCHDFYHALNDLPIIIEGEIIVKALESANMGIPMATLGWMLAPLRLKKAQRDRLYGTYLPWAIKTGLTCKPLINVYWEELLEKDVEELRQELGIKMPPDLRAMRAKRKAMIKRLNEKYQKN
What is the function of this protein?
Component of the coenzyme Q biosynthetic pathway.  May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis.  Required for steady-state levels of other COQ polypeptides.
What are the official names of this protein?
Ubiquinone biosynthesis protein COQ4, mitochondrial, Coenzyme Q biosynthesis protein 4.
What is the protein family that this protein belongs to?
Belongs to the COQ4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: RL32_DROAZ
Sequence: MTIRPAYRPKIIKKRTKHFIRHQSDRYAKLSHKWRKPKGIDNRVRRRFKGQYLMPNIGYGSNKRTRHMLPTGFKKFLVHNVRELEVLLMQNRVYCGEIAHAVSSKKRKEIVERAKQLSIRLTNPNGRLRSQENE
What are the official names of this protein?
60S ribosomal protein L32, Ribosomal protein 49.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL32 family.
Protein: EFG_BARHE
Sequence: MAREYKIEDYRNFGIMAHIDAGKTTMTERILFYTGKNHKIGETHDGASTMDWMEQEQERGITITSAATTTFWEGRDGRKRRFNIIDTPGHVDFTIEVERSLRVLDGAIALLDANAGVEPQTETVWRQAEKYRVPRMVFVNKMDKIGADFYRSVEMVGSRLGAKALVLQLPIGAENDFEGVVDLIEMQALRWDGSIGASATVGEIPSGLKEKAEEYREKLVEMAVEVDEAATEAYLEGVMPTNEQLVALIRKGTVEVQFHPVLCGTAFKNKGVQPLLDAVVSYLPSPVDVPAISGVDVKTEGETTRESSDDAPLSMLAFKIMNDPFVGSLTFCRIYSGKVQKGISLENTVKRKKERLGRMLQMHSNSREDIEEAFAGDIVALAGLKETTTGDTLCDPLKPVILERMEFPEPVIEIAIEPKTKADQEKMGIALNRLAAEDPSFRVKSDEESGQTIIAGMGELHLDIIVDRMRREFKVEANVGQPQVAYRESITKIAEIDYTHKKQSGGAGQFARVKIIFEPHDGDDFIFESKIVGGAVPKEYIPGVQKGIESVMGSGPLAGFPMLGVKATLVDGGYHDVDSSVLAFEIAARAAFRDGAKKAGAQLLEPIMKVEVVTPEDYVGDVIGDLNSRRGQISGTEARGIATVVNAMVPLANMFGYVNSLRSMSQGRAQYTMQFDHYEPVPSAVALEIQKKYA
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MXIC_SHIFL
Sequence: MLDVKNTGVFSSAFIDRLNAMTNSDDGDETADAELDSGLANSKYIDSSDEMASALSSFINRRDLEKLKGTNSDSQERILDGEEDEINHKIFDLKRTLKDNLPLDRDFIDRLKRYFKDPSDQVLALRELLNEKDLTAEQVELLTKIINEIISGSEKSVNAGINSAIQAKLFGNKMKLEPQLLRACYRGFIMGNISTTDQYIEWLGNFGFNHRHTIVNFVEQSLIVDMDSEKPSCNAYEFGFVLSKLIAIKMIRTSDVIFMKKLESSSLLKDGSLSAEQLLLTLLYIFQYPSESEQILTSVIEVSRASHEDSVVYQTYLSSVNESPHDIFKSESEREIAINILRELVTSAYKKELSR
What is the function of this protein?
Necessary for the secretion of IPA invasins.
What are the official names of this protein?
Protein MxiC.
What are the subcellular locations of this protein?
Secreted. Host cell. Note=Secreted via Mxi-Spa type III secretion system (TTSS), and delivered into the host cytoplasm.
Protein: ATPG_MYCVP
Sequence: MAATLRELRGRIRSAGSIKKITKAQELIATSRIAKAQARVEAARPYSAEITSMLTELASASALDHPLLVARENPRRAAVLVVSSDRGLCGAYNANVLRQAEELFSLLREEGKEPVLYTVGRKALGYFSFRQREVVESWAGFSERPTYENAREIADTLVTAFMSGADDEGDDAGADGILGVDELHIVFTEFKSMLSQSAAARRIAPMVVEYVGDEQPEEGPQTLFSFEPDPETLFDALLPRYVATRVYAALLEAAASESASRRRAMKSATDNADDLIKALTLAANRERQAQITQEISEIVGGANALADAK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HFLD_PSET1
Sequence: MNQHQVMALAAMCQVAKQVQKVAQYGNNNEHDLEILLSSIIQTSPASPEDVYQGTDNLRDGYKTLLAQLSAGAQKDVEIVKYVGGLMQLERALSANDKSLNELGKRIDDIHRRLDHFAITDESVVAGLADIYSTVLSPLGHRIQVYGKPELLKQQLTQNKIRALLLAGIRSAVLWRQMGGKRRHFFFAKRKIIAIAKAKI
What are the official names of this protein?
High frequency lysogenization protein HflD homolog.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ACP_BACSU
Sequence: MADTLERVTKIIVDRLGVDEADVKLEASFKEDLGADSLDVVELVMELEDEFDMEISDEDAEKIATVGDAVNYIQNQQ
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCD_PSYWF
Sequence: MTKNNNDLSNSSSNPPSNRPVAGKEAELEIQRETHAAQSGQSESWLSRPIPTVKRNSLPQLTAVETEPSTECPQCHSMITNTALIFNAYVCPHCDHHLAMTARERLTGFLDHIEAELGQEFSASDPLKFVDSKPYPQRMEQMQTKTGETEALIVLQGKLRDMDVVACAFDFRFMGGSMGSVVGDRFVQAAEVALTNKAPLICFAASGGARMQEGVLSLMQMARTSAAIERLRLAGIPYIVVLTNPVYGGVTASLAMLGDIHIAEPKAMIGFAGKRVIEQTVRETLEEPFQRAEYLLEHGVIDQVVHRHQMNDTVYRLLAKLTHV
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_HYDCU
Sequence: MSEIEQTGQSNHYPVMLSESVAGLNIDPNGIYIDCTFGRGGHSRAILNELGEQGRLLAIDQDPEAIRYADANFDDPRFEIQHGSFEALQQYCEARDWVGKIDGILIDLGVSSPQLDEAERGFSFMRSGPLDMRMNPQTGLSAKEWLTQVDEKTLAQVLKQYGEERFSGRIARHIKEAVQEQKLQTTLDLAQVVTKASPKTEKHKHPATRTFQAIRIAVNRELDVLKTVLEVSVAVLKTGGRLSVISFHSLEDRIVKQFIRDQSRIKDLFPDSPIQLEVVEPVIKKVGKPVFPSKEECQENPRSRSAVLRIAERI
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPK_SARBU
Sequence: AGPSATTGVWFGPRL
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Pyrokinin, Neobu-PK, FXPRL-amide.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRI_SALTY
Sequence: MTHDNKLQVEAIKCGTVIDHIPAQVGFKLLSLFKLTETDQRITIGLNLPSGEMGRKDLIKIENTFLTEEQVNQLALYAPQATVNRIDNYDVVGKSRPSLPERINNVLVCPNSNCISHAEPVSSSFAVKKRANDIALKCKYCEKEFSHYVVLAN
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: RPOZ_FINM2
Sequence: MINPSFKKLSEINNSRYALCVMVSKRARMLIDGKETKLKKAKAQPVTTALEEVMEKKVWEDKSNE
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: SRE32_CAEEL
Sequence: MIIKILDPSKNATYLWLPVYFYDEPFQFQILSSIIELVFYISCFHLMTISLYVMLKVQIFHRNLYILYIPMFCVWYGLIAGKLITIAYRLKFVDLDYELGEHIAMWTDDQAKMLHVSSLRGLELLIFGGFVQWHYMYTVVYGILGVAAERAIASVLIENYETNTQLYIPIALTIITQFLAISTSLSVLFHKASVFLSHLPWIISCSLGALAYLFIKIVNENFQKQITNPRRKRLFTISQQFQVKENLRALRLGTRLVFVVFFYVAFVSFGMFALAFDLVSSAYCHFVENFLFLNPYPICFTAMLTIPHWRKHFQNACFTWRLVKSAWTKPKTSTTSVEISTTKKLEAETDLYFRQLNESWI
What are the official names of this protein?
Serpentine receptor class epsilon-32, Protein sre-32.
What is the protein family that this protein belongs to?
Belongs to the nematode receptor-like protein sre family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HEM6_SHEPC
Sequence: MSVPDVAVVKAFLIDLQNRICAGLQALDGQATFAADSWTRAEGGGGTSRVLTQGAVFEQAGVNFSHVTGAAMPASATAHRPELAGRSFEAMGVSLVIHPNNPYIPTTHANVRFFIAQKEGADPVWWFGGGFDLTPYYPFEEDVREWHQTSKDICAPFGDEVYPKYKKWCDEYFFLPHRNETRGVGGLFFDDLNQDGFEQSFSFMQAVGNGFLTAYAPIVERRKETEFGERERQFQLYRRGRYVEFNLVYDRGTLFGLQTGGRTESILMSMPPLVRWQYAYTPEAGSPEADLYDNYLKPRDWV
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HGD_BURTA
Sequence: MERTTIMTLDFSKPGEAGYQSGFANEFATEALPGALPHARNSPQRAPYGLYAEQLSGTAFTAPRGHNRRSWLYRIRPAAVHRPFELVSGERRIVADFGDSGDVPPTPPNQLRWDPLPMPAQPTDFVDGWVTMAGNGSAAAMSGCAIHLYAANRSMRERFFYSADGELLIVPQEGRLFIMTELGRLDVEPFEIAVIPRGVRFAVALPDGRARGYVCENFGALLRLPDLGPIGSNGLANPRDFLTPNASYEDREGAFELVAKLNGRLWRADIDHSPFDVVAWHGNYAPYKYDLRHFNTIGSISYDHPDPSIFLVLQSQSDTPGVDAIDFVIFPPRWLAAEDTFRPPWFHRNVASEFMGLVHGVYDAKAEGFVPGGASLHNCMSGHGPDADTFEKASAIDTSRPNKVGDTMAFMFETRTLIRPTRFALDTAQLQANYFECWQGLKKHFNPEQR
What is the function of this protein?
Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine.  Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
What are the official names of this protein?
Homogentisate 1,2-dioxygenase, HGDO, Homogentisate oxygenase, Homogentisic acid oxidase, Homogentisicase.
What is the protein family that this protein belongs to?
Belongs to the homogentisate dioxygenase family.
Protein: COAA_KLEP3
Sequence: MSQKEQTLMTPYLQFNRHQWAALRDSVPMTLTEDEITRLKGINEDLSLEEVAEIYLPLSRLLNFYISSNLRRQAVLEQFLGTNGQRIPYIISIAGSVAVGKSTTARVLQALLSRWPEHRHVELITTDGFLHPNSVLKERGLMKKKGFPQSYDMHRLVKFVSDLKSGVPQATAPVYSHLIYDVIPDGDKTVAQPDILILEGLNVLQSGMDYPHDPHHVFVSDFVDFSIYVDAPEELLKSWYINRFLKFREGAFTDPDSYFHNYAKLSKEEAVDIATSLWNEINLMNLKENILPTRERASLIMTKSANHSVNQVRLRK
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAHH_PSEA8
Sequence: MSAVMTPAGFTDYKVADITLAAWGRRELIIAESEMPALMGLRRKYAGQQPLKGAKILGCIHMTIQTGVLIETLVALGAEVRWSSCNIFSTQDQAAAAIAAAGIPVFAWKGETEEEYEWCIEQTILKDGQPWDANMVLDDGGDLTEILHKKYPQMLERIHGITEETTTGVHRLLDMLKNGTLKVPAINVNDSVTKSKNDNKYGCRHSLNDAIKRGTDHLLSGKQALVIGYGDVGKGSSQSLRQEGMIVKVAEVDPICAMQACMDGFEVVSPYKNGINDGTEASIDAALLGKIDLIVTTTGNVNVCDANMLKALKKRAVVCNIGHFDNEIDTAFMRKNWAWEEVKPQVHKIHRTGKDGFDAHNDDYLILLAEGRLVNLGNATGHPSRIMDGSFANQVLAQIHLFEQKYADLPAAEKAKRLSVEVLPKKLDEEVALEMVKGFGGVVTQLTPKQAEYIGVSVEGPFKPDTYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROE_RHOP2
Sequence: MHPGDGHTAACLIGWPAAHSRSPLIHHYWLRTLGIPGGYSIESVPPEGFAEFVLNLRAHGYSGANVTIPHKERALQLTQPDDRARAVGAANTLYYDGDVLRSTNTDVEGFIANLDASAPGWDRTPHAVVLGAGGSARAVLFGLLERGIERIALANRSLERAQALADLFGERVVPIAWTDAPAALPGAGLLVNTTSLGMKGQPSLDLDLEPLPSDATVADLVYVPLETELLAEARGRGLRTADGLGMLLHQAVRGFELWFGARPHVTAELRALVEADLAAK
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: NCPP_SALNS
Sequence: MHQVISATTNPAKIQAILQAFEEIFGEGSCHITPVAVESGVPEQPFGSEETRAGARNRVGNARRLHPQADFWVAIEAGIDDDATFSWVVIDNGVQRGEARSATLPLPAVILDRVRQGEALGPVMSHYTGIDEIGRKEGAIGVFTAGKLTRSSVYYQAVILALSPFHNAVYR
What is the function of this protein?
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives.  Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine/xanthosine triphosphatase, ITPase/XTPase, Non-canonical purine NTP phosphatase, Non-standard purine NTP phosphatase, Nucleoside-triphosphate phosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the YjjX NTPase family.
Protein: ENGB_HALWD
Sequence: MSETRPDCDEVVLLGRSNVGKSTLMRELTGHTGFTTGRKPGVTRSPNHYDWASESFMFTDLPGFGFMSGVESSQREQIKTDIVRYIESNAESILAAVLVVDGKSAVEIIDRHSGPDEIPHDIELFSFLWELDLPTVVAVNKIDKVENKDNQLDDLCDRLGLYPPWQQWQDTIAPISAKRGSIEPLEEALQAIFSDQRRDDLLKFVT
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: Z_LYCVT
Sequence: MGQSKSKEEKGISGTSRAEILPDTTYLGPLNCKSCWQKFDSFSKCHDHYLCRHCLNLLLTSSDRCPLCKYPL
What is the function of this protein?
Plays a crucial role in virion assembly and budding.  Expressed late in the virus life cycle, it acts as an inhibitor of viral transcription and RNA synthesis by interacting with the viral polymerase L.  Presumably recruits the NP encapsidated genome to cellular membranes at budding sites via direct interaction with NP.  The budding of the virus progeny occurs after association of protein Z with the viral glycoprotein complex SSP-GP1-GP2 at the cell periphery, step that requires myristoylation of protein Z (By similarity).
What are the official names of this protein?
RING finger protein Z, Protein Z, Zinc-binding protein.
What is the protein family that this protein belongs to?
Belongs to the arenaviridae Z protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm, host perinuclear region. Host cell membrane; Lipid-anchor; Cytoplasmic side. Note=Mainly perinuclear. During budding, associates at the inner side of the plasma membrane of infected cells (By similarity).