PharMolix/UniProtQA huggingface dataset:
Protein: RPIA_BARQU
Sequence: MNVQQLKKRAAAKALEFVQDDMRLGIGTGSTANEFIRLLGERVADGLRVTGVATSQYSEQLCRKFGVPVTTLEQMPELDLDIDGADEIGPEMTLIKGGGGALWREKIVAAASRAMLVIADETKVVKTLGAFALPIEVNPFGMPATRRLIEKVADDLGLSGEIILRMNGENPFKTDGGHFIFDAFWGCILQPRLLSEALLAIPGVVEHGLFWGLASRAIVAMADGQIKVLESSDF
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: REV_SIVGB
Sequence: MSTGNVYQELIRRYLVVVKKLYEEPIPQTARQRRRRKQQLRTRRAQLRELEGRILKQILDRGPDQLCQGVTNLALAEKSESSN
What is the function of this protein?
Escorts unspliced or incompletely spliced viral pre-mRNAs (late transcripts) out of the nucleus of infected cells.  These pre-mRNAs carry a recognition sequence called Rev responsive element (RRE) located in the env gene, that is not present in fully spliced viral mRNAs (early transcripts).  This function is essential since most viral proteins are translated from unspliced or partially spliced pre-mRNAs which cannot exit the nucleus by the pathway used by fully processed cellular mRNAs (By similarity).
What are the official names of this protein?
Protein Rev, Regulator of expression of viral proteins.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Note=The presence of both nuclear import and nuclear export signals leads to continuous shuttling between the nucleus and cytoplasm.
Protein: PROA_MYCLB
Sequence: MRQEVHDAARRARVAARALAVMPTVAKDHALRAAATAVTAHTEEILAANAEDLQAARATDTLAATLDRLALDRQRIDQIAGGLRQVAALPDPIGEVLRGYTLPNGLQLRQQRVPLGVVGMIYEGRPNITVDAFGLAFKSGNAALLRGSSSAAKSNQALVEVLHAALVSEDLPADAVQLLSAADRSTVTHLIQARGLVDVVIPRGGANLIDAVVRDAQVPIIETGVGNCHVYVHQAADLEVAERILLNSKTRRPSVCNAAETLLIDAAIADHTMPRLVAALQGAGVTVHGGLSGDPDKADLCREYLSMDIAVAVVDGVDAAIAHINEYGTGHTEAIVTTNMAAAQRFADGVDSATVMVNASTAFTDGGQFGFGAEIGISTQKLHARGPMGLSEMTSTKWIVWGDGQIRPA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROB_SYNP6
Sequence: MSVQIPVALPQNAYEIAIANGGLAAAGTWLQQADLKAGTKLLIVTNPAIGRRYGDRLVAALQEAGFIVDCLTLPAGERYKTPATVQRIYDKALELRLERRSALVALGGGVIGDMTGFAAATWLRGISFVQIPTSLLAMVDASIGGKTGVNHPRGKNLIGAFHQPKLVLIDPETLQTLPVREFRAGMAEVIKYGVIWDRDLFERLEASPFLDRPRSLPANLLTLILERSCRAKAEVVAKDEKESGLRAILNYGHTIGHAVESLTGYRIVNHGEAVAIGMVAAGRLAVALGLWNQDECDRQEAVIAKAGLPTRLPEGIDQAAIVEALQLDKKVQAGKVRFILPTTLGHVTITDQVPSQTLQEVLQAIANP
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROF_PLALA
Sequence: AILGQDGSVWAQGLHLGGAKYVIAGEPGAVIRLGDYLLDQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.
What are the official names of this protein?
Profilin.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: ADDB_ACET2
Sequence: MSLRFIYGRAGSGKTRFCLEEIKSRITSKATHPLVLLVPEQFTFQAERDLISVLGTGGILKTEVLSFSRIAYRTFNEAGGITYPHIHSAGKCMILYRILDKMKGSFRVFSKTADRQGFVNTLSTLITEFKKYNVTPEDLEKVSKELEEDNPVKEKLMELTAIYDLFEKTIAERYRDPDDDLTLAAKKLGSIPLYDGAEIWIDGFTGFTPQEYQIIGQLMKKAQRVNISFCTDCLDGDLNDTDIFSSIKTAYRKLVKMAKENGIPVEPSVVLNSKPLFRFSQSPELSHLEQYLYAYPYKTYNEKTKDISLFSSVNIFAEVEACARDIVRLCRDRGMRYREIAVVTGNLDGYEKLIEAVFSEYGIPCFIDRKVDIVNHPLVRLIMSMLDIFIENWSYEAVFRYLKTGLTGIDRESIDRLENYVLACGIRGSCWTETEEWKMVPELIPNEKSLEEAKELLEDVNRIRAQVVAPLMEFRKKTKGRKKASDFCASLYDFLCTLGIPEKIEDAIEKFRESGNLNLANEYSQVWNAVMEVFDHTVEVMGDETFGIEKFARILEIGFGECKIGLIPASLDQVLVGSLERSRSHEIKALYILGANDGVFPPAVMEEGILSDQDRAVLNNAGIELASDTRTQAFDGQYLIYRALTTAGNYLRISWSIADHEGRTLRPSLVVFRLRKLFLNITETSNILPSGSLEEEMELLSGNSPAFKSMVSALRQKADGKEIKPVWQEAYRWFAVQDEWRGKCEALRAAFQYKNLAQPVSREKIAALYGEPAVSSVSRLEKYTACPFAFYVQYGLGAKERQIYSLRPPDVGTFMHAVIEKFSRMVAKRNISWRDLDRDWCSEKVSEIVDEMLEKMQGSGIAASRRYTALTLRLKRVVARAVWLIAEHIRRSSFEPVAYEVGFGENGKYPPIVIELDSGEKIHLTGRIDRVDALKTEDGTYLRIVDYKSGGKDFKLSDVFYGLQIQLITYLDALWESGEADENNPVLPGGVLYFKIDDPIIRGNGRMTEEEIEKAIMKQLRMKGLLLADVKLIREMDKDIEGSSMIIPATVNKDGSLGKNTSAATMEQFKLLRKYVRKLLKNLCEEIMKGNVSINPYKKKGTTSCKYCSFLPVCQFDTTMKENTFKLLYDKKDDEIWSLMAQEEEE
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease AddB, DNA 3'-5' helicase AddB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 1 subfamily.
Protein: RL28_XYLFM
Sequence: MSRVCQVTGKRVQTGNNVSHANNKTRRRFLPNLHKRRFWVASENRWVKLRVSTCAVRTIDKNGIDAVLAELRASGEKV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: RL22_BURCH
Sequence: MEVKAIHRGARISAQKTRLVADQIRGLPVDKALNVLTFSPKKAAGIVKKVVLSAIANAEHNEGADIDELKIKSIYVDKAASLKRFTARAKGRGNRIEKQSCHITVTVGN
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: AEF1_GIBZE
Sequence: MRKDTYSSLISTAFSALSCKPPKHHSIVSPETENLTPSSDVALNIDTPKSINNNLFHRQKPVHSSQETSNYFLQRPFHPKTDVAAVDAMTEVGAADLSRLLQSKRNECSSIVTSRKRKLRELFVVATQSEGLPHPVLTNPDAPTTTPAEWQFLQANDINQSKTLNEASIPTRPTFSLEVLKKSLAKSIFIANESVPKQTSENSNKSHVTDAQDEQQSNRASLSTKSDAAATSTRPNTPETSTESATTANPVPPPAKNTQAVLPPADAIEKPIPTTSPDVPASTGANANSITNEEDRSDPNEVASVPRQPQVTFETGTKGEHVETGTSSVKSGHGVGDSAVTTGVPSTVKPSADVTRSADALSSPGSTAQSATTPAVHDDASTDTSPEHEGPQYVEPAEQKKIEDGTHERDTDKYHQSHQDGDIRAPSTKDLEDRVLEAPPDSAEAQLLQESIRSNVAAENEAALNSESTSQEADTAISAPVSEDVNMSDVDDRVVKAAPTVGEKVEEKRAQQILDTDAKSALATGAPAEISGSKEIPDSQEEAPEQMDVDAPEPKASTESQIGAPISLEKLDAADTGPSSPTPAHIAEVATPPEPVRQNSPPKAERAVTRVSSGAMRPKSVSEIVGVTPRQTPTLEHISTNKSTNHQLTPLTSTPKSPTLRHRHISAHQRQASRSQPSTVVFGKQSKKGEEKSMVTSQHDTILPTEDYYTPLFVQGFAGSSSWMQPIEKILYTANKTVTTPDANLAIQDHQACKVLRRVYHLQQHDKWSLRQPKRCPEPTRPPSHWDVVLQEMKWMRTDFREERKWKRAVAKNLAYACAEWHEATPEERKTLQVQAVVPPKMKPASDVAMVDAEGTNHLTPDLVSSEDVESIDNLDDLIEDFPETIAPSAIFNLQDEDVVFGLRRTAAADQLLEELPMFGAPLQVPKFDLTGPEWDPDAHWRRPALPLSKYVEGHMKLVSDGPPRKRSRYNYQNEDSDDEGEAGFVSSDSTPSLPLPSATDEVALFNPEMKHIRDRLYVGHQFRPPSEYPMPSQSFFECRSPSQWTIAEDDELRSLVREHSYNWSLISSILAPRSIFNSGAERRTPWECFERWINLEGLPADMSKTQYFKAYMGRINTAQNMINIQNQAMAQQQVNQANGAVTPGRRRHQSIPFRVERRRNQKHLTMLDAMRKLAKKRETTAQKQQHTASQNAANKKTNESASQRPTKTPGEYSRLRYERDQALAEKMAQFASRQEAQRRAVLQARAQGQAAQMAAGTPAAVQAGQNSAQAAAAAAAAAAAANGMNGVGRVNVPNQLAAAAAAATGQARPRMPMQSPAPASMGGVPAHMASGLVPPNQMNSVQQAQMQAMQAMQGQHNRMPMPNPPPDVSLMMRAQRISEQQRAAQMHAQGGPGTPGQGAVGAQQSPPAQMRNAMNGVNGINSNPMNQQSFLNNAQAMMAQFNQGNLSSPQANGLHMPSGPAGSIAPRPQTQLPAAIQAQLNQLEAQYRAKNSSLTSEQARQMATEHLTRLMMAQRSAMNAAAGTAGGQGGLAGSIAATTSPHQYAALLRQQQQQQASAAAGSPGQQHQQPHQAQHQPQQQQSQQQQAQAKQQQPQQQVQAHAHAQAQHQAQQQQQQQRQASGSATPSAG
What is the function of this protein?
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A.  The NuA4 complex is also involved in DNA repair (By similarity).
What are the official names of this protein?
Chromatin modification-related protein EAF1, ESA1-associated factor 1, Vacuolar import and degradation protein 21.
What is the protein family that this protein belongs to?
Belongs to the EAF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYD_FLAJ1
Sequence: MYRSHNCGELNASNINTEVTLAGWVQKSRDKGFMNWVDLRDRYGITQLIFDESRTDKTVFELAKTLGREFVIQVKGTVIEREAKNKNIPTGEIEILVSELTILNTALTPPFTIEDETDGGEDIRMKYRYLDIRRNPVKNSLLFRHKVAMEVRKYLSDLDFCEVETPYLIKSTPEGARDFVVPSRMNEGQFYALPQSPQTFKQLLMVGGMDKYFQIVKCFRDEDLRADRQPEFTQIDCEMAFVEQEDILNVFEGLTRHLLKEIKGIEVDKFPRITYDYAMKTYGNDKPDIRFGMKFGELNEFAQHKEFPVFNAAELVVGIAVPGAGNYTRKEIDGLIDWVKRPQVGASGMVYVKCNEDGTYKSSVDKFYDNDDLAKWAKATEANPGDMIFVLSGPANKTRAQLSALRMELATRLGLRNPEEFAPLWVVDFPLLELDEESGRYHAMHHPFTSPKPEDMALLETEPGKVRANAYDMVLNGNEIGGGSIRIHDKATQQLMFKYLGFTEEEAKAQFGFLMDAFQFGAPPHGGLAFGLDRLVAILGGQETIRDFIAFPKNNSGRDVMIDAPAAIDDAQLKELHIKIDSI
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK14_LOBMA
Sequence: MIQPQTYLNVADNSGARELMCIRIIGASNRRYAHIGDVIVAVIKEAIPNTPLERSEVIRAVIVRTCKELKRNNGTIIRYDDNAAVVIDQEGNPKGTRVFGAIPRELRQLNFTKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: COMB_GLOVI
Sequence: MQVSVFHTPELVPEGTPDCAVAVDVLRATSTIATALANGATAVQVYADLEALGAAAAGYPREDILRGGERGGKQVEGFDFGNSPLYCTSERVAGKRIFMSTTNGTRTLERIRHAPVVLTAALVNVGFVARYIRSQAFETVWVVGSGWQGNFSLEDTVCAGALVEQLGGAANDEAVAAAALFDTWEGDLIELLERASHGQRLLKLGLLDDIVYCAALDTVSALPRQTAAGVLVQGMA
What are the official names of this protein?
Probable 2-phosphosulfolactate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the ComB family.
Protein: ATPA_SULSY
Sequence: MSVIRADEVLESLNKQIEEFQVSANLEEVGTVIQVGDGVARIYGLEKAMMGEMLEFESGIVGVVFNLEEDNVGAVLLGSDVAVREGSIVKRTGKILSVPVGKGLLGRVVDGLGNPIDGKGPLTDIAYYSPVEKIAPGVVKRKSVHEPLQTGIKAIDAMIPIGRGQRELIIGDRATGKTTIAIDTILNQKGQGVYCIYVAIGQKRANVVHIVETLQKHGAMEYTTVVAATSSDPATMQYIAPFVGCTIGEYFRDNGMHALVIYDDLTKHAYAYRQLSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDELGAGSLTALPIIETQAGDVAAYIPTNVISITDGQIFLEADLFYKGIRPAINAGISVSRVGGAAQIKAMKQVAGTLRLDLAQYRELEAFVQFASELDKATQAQIARGQRMVELLKQPPNQPVPVEKQVAIIYVAGQGYLDDVSVNAIQKFEKEFYVFLDTEKPDILEAIRREKALTDDIKAKLDAAVKEFKQKVAF
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL11_CUPMC
Sequence: MAKKIIGFIKLQIPAGKANPSPPVGPALGQRGLNIMEFCKAFNAQTQGMEPGLPVPVVITAFADKSFTFVMKSPPATVLIKKAAGITKGSPKPHTDKVGKITRAQAEEIAKAKNADLTAADLDAAVRTIAGSARSMGITVEGL
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RIMO_BURM7
Sequence: MENSLKSSGKPLAAPKVGMVSLGCPKALVDSEQIITQLRAEGYEISGTYDGADLVVVNTCGFIDEAVQESLDAIGEALAENGKVIVTGCLGAKKSASGSGLIAEVHPKVLAVTGPHAVGEVMQAVHSHLPKPHDPFVDLVPAAGIKLTPRHYAYLKISEGCNHRCSFCIIPSMRGELVSRPVAEVMLEAENLFKSGVKELLVISQDTSAYGVDVKYRTGFWNGRPLKTRMTELVGALGELAAQYGAWVRLHYVYPYPHVDEIIPMMAQGPLKGHVLPYLDVPFQHAHPEVLKRMKRLANAERVLERVQKWREICPDLTIRSTFIAGFPGETDAQFETLLDFIREAELDRVGCFAYSPVEGASANALDGALPDDVREARRARFMEVAEEVSAARIARKIGKTLKVLIDEVNAEGGIGRTAADAPEIDGVVYVEPAAKASKRYKVGEFVSVKITGADGHDLWGEV
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLHD_SALPB
Sequence: MHTSELLKHIYDINLSYLLLAQRLIVQDKASAMFRLGINEEMANTLGALTLPQMVKLAETNQLVCHFRFDDHQTITRLTQDSRVDDLQQIHTGIMLSTRLLNEVDDTARKKRA
What is the function of this protein?
Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region.  Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes.  Also regulates genes whose products function in a variety of physiological pathways.
What are the official names of this protein?
Flagellar transcriptional regulator FlhD.
What is the protein family that this protein belongs to?
Belongs to the FlhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_ENHLU
Sequence: MTNIRKTHPLTKIINNSFIDLPAPSNISAWWNFGSLLGICLILQILTGLFLAMHYTSDTTTAFSSVAHICRDVNYGWIIRYMHANGASMFFICLFLHVGRGLYYGSYMFSETWNIGIVLLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIISALAMIHLLFLHETGSNNPSGIPSNSDKIPFHPYYTIKDILGALSLVLALTTLVLFSPDLLGDPDNYIPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSILILAIIPLLHTSKQRSMMFRPLSQCLFWLLVADLLTLTWIGGQPVEHPFVVIGQLASILYFMILLVLMPITSIIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SYR_GEOTN
Sequence: MNIVGQMKEQLKEEIRQAVGKAGLVAAEELPEVLLEVPREKAHGDYSTNIAMQLARIAKKPPRAIAEAIVEKFDAERVSVARIEVAGPGFINFYMDNRYLTAVVPAILQAGQAYGESNVGKGEKVQVEFVSANPTGNLHLGHARGAAVGDSLSNILAKAGFDVTREYYINDAGKQIYNLAKSVEARYFQALGTDMPLPEDGYYGDDIVEIGKKLADEYGDRFVHVDEEERLAFFREYGLRYELDKIKNDLAAFRVPFDVWYSETSLYESGKIDEALSTLRERGYIYEQDGATWFRSTAFGDDKDRVLIKQDGTYTYLLPDIAYHQDKLRRGFTKLINVWGADHHGYIPRMKAAIAALGYDPEALEVEIIQMVNLYQNGERVKMSKRTGKAVTMRELMEEVGVDAVRYFFAMRSGDTHLDFDMDLAVAQSNENPVYYVQYAHARVSSILRQAKEHQLSYEGDVDLHHLVETEKEIELLKALGDFPDVVAEAALKRMPHRVTAYAFDLASALHSFYNAEKVLDLDQIEKTKARLALVKAVQITLQNALALIGVSAPEQM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YSH1_YEAST
Sequence: MERTNTTTFKFFSLGGSNEVGRSCHILQYKGKTVMLDAGIHPAYQGLASLPFYDEFDLSKVDILLISHFHLDHAASLPYVMQRTNFQGRVFMTHPTKAIYRWLLRDFVRVTSIGSSSSSMGTKDEGLFSDEDLVDSFDKIETVDYHSTVDVNGIKFTAFHAGHVLGAAMFQIEIAGLRVLFTGDYSREVDRHLNSAEVPPLSSNVLIVESTFGTATHEPRLNRERKLTQLIHSTVMRGGRVLLPVFALGRAQEIMLILDEYWSQHADELGGGQVPIFYASNLAKKCMSVFQTYVNMMNDDIRKKFRDSQTNPFIFKNISYLRNLEDFQDFGPSVMLASPGMLQSGLSRDLLERWCPEDKNLVLITGYSIEGTMAKFIMLEPDTIPSINNPEITIPRRCQVEEISFAAHVDFQENLEFIEKISAPNIILVHGEANPMGRLKSALLSNFASLKGTDNEVHVFNPRNCVEVDLEFQGVKVAKAVGNIVNEIYKEENVEIKEEIAAKIEPIKEENEDNLDSQAEKGLVDEEEHKDIVVSGILVSDDKNFELDFLSLSDLREHHPDLSTTILRERQSVRVNCKKELIYWHILQMFGEAEVLQDDDRVTNQEPKVKEESKDNLTNTGKLILQIMGDIKLTIVNTLAVVEWTQDLMNDTVADSIIAILMNVDSAPASVKLSSHSCDDHDHNNVQSNAQGKIDEVERVKQISRLFKEQFGDCFTLFLNKDEYASNKEETITGVVTIGKSTAKIDFNNMKILECNSNPLKGRVESLLNIGGNLVTPLC
What is the function of this protein?
Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB.  Has endonuclease activity.
What are the official names of this protein?
Endoribonuclease YSH1, Yeast 73 kDa homolog 1, mRNA 3'-end-processing protein YSH1.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
Protein: F174C_HUMAN
Sequence: MGPRVLQPPLLLLLLALLLAALPCGAEEASPLRPAQVTLSPPPAVTNGSQPGAPHNSTHTRPPGASGSALTRSFYVILGFCGLTALYFLIRAFRLKKPQRRRYGLLANTEDPTEMASLDSDEETVFESRNLR
What are the official names of this protein?
Protein FAM174C.
What is the protein family that this protein belongs to?
Belongs to the FAM174 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: DDX31_HUMAN
Sequence: MAPDLASQRHSESFPSVNSRPNVILPGREGRREGLPPGGGTRGSLVPTRPVPPSPAPLGTSPYSWSRSGPGRGGGAGSSRVPRGVPGPAVCAPGSLLHHASPTQTMAAADGSLFDNPRTFSRRPPAQASRQAKATKRKYQASSEAPPAKRRNETSFLPAKKTSVKETQRTFKGNAQKMFSPKKHSVSTSDRNQEERQCIKTSSLFKNNPDIPELHRPVVKQVQEKVFTSAAFHELGLHPHLISTINTVLKMSSMTSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQAMESKIQRSDGPYALVLVPTRELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHIKSTKNIHFSRLRWLVFDEADRILDLGFEKDITVILNAVNAECQKRQNVLLSATLTEGVTRLADISLHDPVSISVLDKSHDQLNPKDKAVQEVCPPPAGDKLDSFAIPESLKQHVTVVPSKLRLVCLAAFILQKCKFEEDQKMVVFFSSCELVEFHYSLFLQTLLSSSGAPASGQLPSASMRLKFLRLHGGMEQEERTAVFQEFSHSRRGVLLCTDVAARGLDLPQVTWIVQYNAPSSPAEYIHRIGRTARIGCHGSSLLILAPSEAEYVNSLASHKINVSEIKMEDILCVLTRDDCFKGKRWGAQKSHAVGPQEIRERATVLQTVFEDYVHSSERRVSWAKKALQSFIQAYATYPRELKHIFHVRSLHLGHVAKSFGLRDAPRNLSALTRKKRKAHVKRPDLHKKTQSKHSLAEILRSEYSSGMEADIAKVKKQNAPGEPGGRPLQHSLQPTPCFGRGKTLKWRKTQKGVQRDSKTSQKV
What is the function of this protein?
Probable ATP-dependent RNA helicase (By similarity).  Plays a role in ribosome biogenesis and TP53/p53 regulation through its interaction with NPM1 (PubMed:23019224).
What are the official names of this protein?
Probable ATP-dependent RNA helicase DDX31, DEAD box protein 31, Helicain.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX31/DBP7 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Note=Colocalized with NPM1 in the nucleoli.
Protein: PA2B2_CROMT
Sequence: SLLQFNKMIKFETRKNAIPFYAF
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that shows presynaptic neurotoxicity.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Basic phospholipase A2 CB2, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YJGA_ESCF3
Sequence: MTKQPEDWLDDVPGDDIEDEDDEIIWVSKSEIKRDAEELKRLGAEIVDLGKNALDKIPLDADLRAAIELAQRIKMEGRRRQLQLIGKMLRQRDVEPIRQALDKLKNRHNQQVVLFHKLENLRDRLIDQGDDAIAEVLNLWPDADRQQLRTLIRNAKKEKEGNKPPKSARQIFQYLRELAENEG
What are the official names of this protein?
UPF0307 protein YjgA.
What is the protein family that this protein belongs to?
Belongs to the UPF0307 family.
Protein: RGS9_RAT
Sequence: MTIRHQGQQYRPRMAFLQKIEALVKDMQNPETGVRMQNQRVLVTSVPHAMTGGDVLQWIIQRLWISNLEAQNLGNFIVKYGYIYPLQDPKNLVLKPDSSLYRFQTPYFWPTQQWPAEDTDYAIYLAKRNIKKKGILEEYEKENYDFLNKKINYKWDFVIMQAKEQYRTGKERNKADRYALDCQEKAYWLVHRSPPGMNNVLDYGLDRVTNPNEVKKQTVTAVRKEIMYYQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQFWDLNAKLVEVPTKMRVERWAFNFSELIRDPKGRQSFQYFLKKEFSGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLRHPHRYVLDAAQTHIYMLMKKDSYARYLKSPIYKEMLAKAIEPQETTKRSSTLPFMRRHLRSSPSPVILRQLEEEERAREAANTVDITQPGQHLAPSPHLAVYTGTCVPPSPSSPFSPSCRSPRKPFPSPSRFIRRPSIAICPSPIRVALEGSSGLEGKGEASWSGANPGPPVTESIETSVDRSRPHSQPRAPLKARAALSLGRFLRRGCLASPVFARLSPKCPSVSHGKVQPLGDMGQQLPRLKPKKVANFFQIKMEMPTDSGPCLMDSDDPGAGESGDQTTEKEVICPWESLAEGKAG
What is the function of this protein?
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.  Binds to GNAT1.  Involved in phototransduction; key element in the recovery phase of visual transduction (By similarity).
What are the official names of this protein?
Regulator of G-protein signaling 9, RGS9.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Note=Targeted to the membrane via its interaction with RGS9BP.
Protein: PROB_RHIL3
Sequence: MTSRKPLGRYRRIVIKIGSALLVDRKAGLKKAWLDAMCADISGLKAKGIDVLVVSSGAIALGRSVLDLPSGALKLEESQAAAAVGQIALARAWSESLSRDEIVAGQILLTLGDTEERRRYLNARATINQLLKIGAVPIINENDTVATSEIRYGDNDRLAARVATMTGADLLILLSDIDGLYTAPPHLDPNATFLETIAEITPEIEAMAGGAASELSRGGMRTKIDAGKIATASGCAMIIASGKTENPLSAIENGARSSWFAPSGTPVTARKTWIAGQLQPAGELHVDDGAVTALGAGKSLLPAGVRSVSGLFSRGDTVAIIGPAGREIARGLVSYDADDARRIAGRKSAEIETILGYPGRAAMVHRDDMVMTAQIGSKSERQKKDASYA
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRE_METEP
Sequence: MTPEEVLEEFRSAGALLQGHFILSSGLRSPTFLQKMTIFSDPARTERLCRALAEVITARFGRIDIVVSPAIGGIIPGYETARHLGAKAIFVERDPGGPFTLRRGFSIPAGTRAVIVEDIVTTGLSARECLASLKDEAGEVVGAACLIDRSGGRGAIGLPLLSLVTLDIPTYAPDALPAELAAIPPVKPGSRALPKP
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: HEMH_YERE8
Sequence: MKQSKLGVLMVNLGTPDAPTPQAVKRYLAEFLSDRRVVDTSPWLWWPLLRGVILPIRSPRVAKLYQSVWMDEGSPLLVYSRRQQKALAERMPEIPVELGMSYGSPNLPDAIDKLLAQGVTKLVVLPLYPQYSCSTSAAVWDAVARILQGYRRLPSISFIRDYAEHPAYISALKQSVEHSFVQHGKPDRLVLSFHGIPKRYAQLGDDYPQRCEDTSRALRAEIALPAEQIMMTYQSRFGREPWLTPYTDETLKSLPSQGVKHIQLICPGFSADCLETLEEIKEQNREIFLHAGGEKFEYIPALNDDKGHIDLLEQLVRDHLSC
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.