PharMolix/UniProtQA huggingface dataset:
Protein: RUVA_CORA7
Sequence: MIASLRGTVLDIQLDHAVLECAGVGYKVLATPAMLGTLQRGEEARVMTTLVVKEDSMTLYGFTSQDDRDMFHVLQTVSGLGPKLALAALSVMSAGDLAQAIAGEEAARLQKIPGVGKRVAQRLILELKDKVKAFAPAESADLSSAAPAAAGPVVEDVVEALIGLGFTDKMARPVVESVVAEQPDAATPVVLRAALSQLGAKK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: PIANP_HUMAN
Sequence: MESRMWPALLLSHLLPLWPLLLLPLPPPAQGSSSSPRTPPAPARPPCARGGPSAPRHVCVWERAPPPSRSPRVPRSRRQVLPGTAPPATPSGFEEGPPSSQYPWAIVWGPTVSREDGGDPNSANPGFLDYGFAAPHGLATPHPNSDSMRGDGDGLILGEAPATLRPFLFGGRGEGVDPQLYVTITISIIIVLVATGIIFKFCWDRSQKRRRPSGQQGALRQEESQQPLTDLSPAGVTVLGAFGDSPTPTPDHEEPRGGPRPGMPHPKGAPAFQLNRIPLVNL
What is the function of this protein?
Acts as a ligand for PILRA in neural tissues, where it may be involved in immune regulation.
What are the official names of this protein?
PILR alpha-associated neural protein, PILR-associating neural protein, Paired immunoglobin-like type 2 receptor-associating neural protein.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: CH60_ACICJ
Sequence: MAAKDVRFSADARERLIRGVDLLANAVKVTLGPKGRNVVIEKSFGSPRITKDGVTVAKEIELADKFENMGAQMVREVASKTNDLAGDGTTTATVLAQAIVREGAKAVAAGMNPMDLKRGIDKAVNAIVDELKKRTKKITTPSETAQVGTISANGEAEIGKMISEAMQKVGNEGVITVEEAKGIQTELDVVEGMQFDRGYVSPYFITNPEKMVADLDNPYILIHEKKLSGLQPMLPLLESIVQSGKPLLIIAEDVEGEALATLVVNKLRGGLKIAAVKAPGFGDRRKAMLEDIAILTGGQVISEDLGIKLETVTLNMLGRAKKVLIEKENTTIVEGAGKKADITGRCNQIRAQIEETTSDYDREKLQERLAKLAGGVAVIRVGGASETEVKERKDRVDDALHATRAAVEEGIVPGGGVALARASLAINKLKADNDDQRFGIDIIRKAVLAPMRQIAENAGEDGAVISGKVLDNDDYSFGFDAQSGEFKDMVKAGIIDPTKVVRTALQDAASVAGLLITTEAMVAERPEKKAPAGGDAGMGGMGGMGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIF3L_DANRE
Sequence: MSYPAEEEDVNYDPYSYPNDYDYHTGDPKADLAYERQYEHQQTYHVIPEVIKNFLQYFHKTISDLIDQKVYELQANRVSSESIEQKIYEIQDVYENSWNKLTDRFFKTSPWPEAEAIASLVGNDAVFLILYKELYYRHIYAKVSGGPTLDQRFESYYNYCNLFNYILNADGPAPLELPNQWLWDIIDEFIYQFQSFSQYRCKTAKKSEEEIEFLRNNPKIWNVHSVLNVLHSLVDKSNINRQLEVYTSGGDPESVAGEYGRHSLYKMLGYFSLVGLLRLHSLLGDYYQAIKVLENIELNKKSMYSRVPECQITTYYYVGFAYLMMRRYQDAIRVFANILLYIQRTRNMFQRTTYKYEMINKQNEQMHGLLAIALTMYPMRIDESIHTQLREKYGDKMLRMQKGDLQVFEELFSFACPKFLSPVVPNYENVHPNYHKEPFQQQLKVFAEEVQQQAQLSTIRSFLKLYTTMPVAKLAGFLDMSEQEFRIQLLVFKHKMKNLVWTSGISALDGEFQSASEVDFYIDKDMIHIADTKVARRYGDFFIRQIHKFEELNRTLKKMPLNTGASISSSSTSRAT
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit L, eIF3l, Eukaryotic translation initiation factor 3 subunit 6-interacting protein, Eukaryotic translation initiation factor 3 subunit E-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit L family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_METS4
Sequence: MHDIRVIRDNPAAFDAGLRRRGLEPLAAELVALDDARKAAISAAQVAQERRNALSKEIGAAKKARDEERARALMAEVARLKEQAPGLDAAADAAARALDARLAAIPNTPGPEVPEGRDEHDNVELRRFEGRGRAESGRQHFELGEAAGLMDFEAAARLSGSRFVVLKGRLARLERALGQFMLDLHTAEHGYTEVAPPLLVRDEAMFGTAQLPKFRDDQFAAQPGAVEPGAPGRWLIPTAEVPLTNLVRESILSEDELPLRFTALTPCFRAEAGAAGRDTRGMLRQHQFTKVELVSITAPEQSAEEHERMLACAEAVLRRLDLPYRVMTLCTGDMGFASQKTYDIEVWLPGQGTYREISSCSVCGDFQARRMEARFRRREDRGLGYVHSLNGSGVAVGRALIAVMENYQNPDGSVTVPSALAPYMGGVTRIEGPHA
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPRC1_CANPA
Sequence: MSLAGKEFKLSNGNKIPAVAFGTGTKYFKRGHNDLDKQLIGTLELALRSGFRHIDGAEIYGTNKEIGIALKNVGLNRKDVFITDKYNSGNHTYDGKHSKHQNPYNALKADLEDLGLEYVDLYLIHFPYISEKSHGFDLVEAWRYLERAKNEGLARNIGVSNFTIENLKSILDANTDSIPVVNQIEFSAYLQDQTPGIVEYSQQQGILIEAYGPLGPITQGRPGPLDKVLSKLSEKYKRNEGQILLRWVLQRGILPITTTSKEERINDVLEIFDFELDKEDEDQITKVGKEKTLRQFSKEYSKYD
What is the function of this protein?
NADPH-dependent conjugated polyketone reductase with broad substrate specificity and strict stereospecificity.  Reduces ketopantoyl lactone (2-dehydropantolactone) and isatin.  Does not act on menadione, p-nitrobenzaldehyde and pyridine-3-aldehyde.
What are the official names of this protein?
NADPH-dependent conjugated polyketone reductase C1, CPR-C1, 2-dehydropantolactone reductase, Ketopantoyl-lactone reductase.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
Protein: RLME_ACTPJ
Sequence: MGRKRSASSSRWLAEHFKDQFVQKAHKQKLRSRAYFKLDEIQQTDRLFKPGMTVVDLGAAPGGWSQYAVTQIGSKGRIIACDILDMNPIVGVDFLQGDFREESVLNALLERVGDDMVDVVMSDMAPNFSGMPSVDIPRAMYLVELALDMCRQVLAPKGSFVVKVFQGEGFDDYLRDIRAMFTTVKVRKPEASRDRSREVYIVATGYKG
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYA_FRATN
Sequence: MITTKELRNKFINYFESKNHSHQPSSSLIPFGDDTLLFTNAGMVQFKDVFLGIEKKDFSRAVTVQKCLRAGGKHNDLDNVGYTARHHTFFEMLGNFSFGDYFKKDAISFAWEFLTKEIKLPIEKLWVTIYASDDEAFDVWHKHIGLAKERIIRIDSSDNFWSMGDTGPCGPCTEIFYDHGEDVAGGLPGTPEQDGDRYIEIWNIVFMQYNRHADGSTTDLPKPSVDTGMGLERISAVLQNVHSNYEIDLFQALIKKAQQVTHAKDINSPSLKVIADHIRACAFLIADGVLPANEGRGYVLRRIIRRAIRHGNKVGAKEIFFYKLVAELVNQMGEAYSQLIDKRELIEKTLIKEEELFLKTIENGIKIFDAEIENLKDNTISGEVAFKLYDTYGFPFDLTADMAREKGLKVDEQAFLAQMQIQKQRSKEAGKFNVDYNSLINSQVKSEFRGYSTLIEDAKVLEIYQDGQLVASTSEQVPAVVVLDKTPFYAESGGQVGDKGILEGVGFEFVVEDVQKSGEAILHIGKLVKGRLNLNDELTARVSDQPRLATAANHSATHLLHKALKLVLGGHAEQKGSLVDENRLRFDFTHDKAISRSEIEQIELLVNQQIRANYPVTTIETSQQKAKSLGAEALFGEKYGDIVRVISMGDFSIELCGGTHVAYTGDIGLFKIISEGGIASGVRRIEAVTADKAIRHTFTNENKIIAIKDSLKANDANLIDKIKSMLEQIKNQEKQIAKLKKELLSGSSNDIKETNIGDIKVVVANVDGVDVKTLRDKIDDYKSKNTKVIAVLTTTNADKVQFVIGVSNAITTLIKAGDIAKELSSHIDGKGGGRADMAQGGGNNSANIDQALSQVEKFILNNIKE
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XYNB_EMENI
Sequence: MVSFSSLLLACSAVTAFAAPSDQSIAERSLSERSTPSSTGTSGGYYYSFWTDGGGDVTYTNGDGGSYTVEWTNVGNFVGGKGWNPGSSQTISYSGSFNPSGNGYLSVYGWTQNPLIEYYIVESYGDYNPGTAGTHQGTLESDGSTYDIYTATRENAPSIEGTATFTQFWSVRQSKRTSGSVTTQNHFDAWSQLGMTLGTHNYQIVAVEGYQSSGSASITVS
What is the function of this protein?
Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.
What are the official names of this protein?
Endo-1,4-beta-xylanase B, Xylanase B, 1,4-beta-D-xylan xylanohydrolase B, 24 kDa xylanase, Endo-1,4-beta-xylanase G1, Xylanase G1, Xylanase X24.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 11 (cellulase G) family.
What are the subcellular locations of this protein?
Secreted.
Protein: GUAC_STRA5
Sequence: MFNDIPVFDYEDIQLIPNKCIISSRSQADTSVKLGNYTFKLPVIPANMQTIIDEEVAETLACEGYFYIMHRFNEEERKPFIKRMHDKGLIASISVGVKDYEYDFVTSLKEDAPEFITIDIAHGHSNSVIEMIQHIKQELPETFVIAGNVGTPEAVRELENAGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCSKAARKPIIADGGIRTHGDIAKSIRFGASMVMIGSLFAGHLESPGKLVEVEGQQFKEYYGSASEYQKGEHKNVEGKKILLPVKGRLEDTLTEMQQDLQSSISYAGGKELDSLRHVDYVIVKNSIWNGDSI
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
Protein: ARF_MAIZE
Sequence: MGLTFTKLFSRLFAKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRDRVVEARDELHRMLNEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLNSLRQRHWYIQSTCATTGEGLYEGLDWLSSNIATKS
What is the function of this protein?
GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
What are the official names of this protein?
ADP-ribosylation factor.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: FND11_BOVIN
Sequence: MNFQVTGLGLDKIKLDSPQSFLDQEEVEEAEDGQLLEPEAWRTYVERRNALQEFLTSDLSPHLLKRHHARMELLKKCSYYIEILPKHLALGDQNPLVLPTTMFQLIDPWKFQRMKKVGAAQTKIQLLLLGDLLEQLDHGRSELDALLESPDPRPFLAGWGLVEQRLADLSAVMDSFLAMMVPGRLHIKHRLVSDIGATKIPHIRLMLSTKMPVMFDRKESVAHQDWVSLRWFVTIQQAVPEQFELRYKLLDPRTQQECMQCGIIPVAACAFDIRNLLPNRAYKFTVKRAESYTLVYEPWRDSLTLHTRPGPPEGLAPSRLGKLGLSLTTPSER
What are the official names of this protein?
Fibronectin type III domain-containing protein 11.
Protein: CATA_CANTR
Sequence: MAPTFTNSNGQPIPEPFATQRVGQHGPLLLQDFNLIDSLAHFDRERIPERVVHAKGSGAYGVFEVTDDITDVCAAKFLDTVGKKTRIFTRFSTVGGELGSADTARDPRGFATKFYTEEGNLDLVYNNTPVFFIRDPSKFPHFIHTQKRNPETHLKDANMFWDYLTTNEESVHQVMVLFSDRGTPASYREMNGYSGHTYKWSNNKGEWFYVQVHFISDQGIKTLTNEEAGSLAGSNPDYAQEDLFKNIAAGNYPSWTCYIQTMTEAQAKEAEFSVFDLTKVWPHGKYPMRRFGKFTLNENPKNYFAEVEQAAFSPAHTVPHMEPSADPVLQSRLFSYADTHRHRLGTNYTQIPVNCPVTGAVFNPHMRDGAMNVNGNLGNHPNYLASDKPIEFKQFSLQEDQEVWHGAATPFHWKATPADFKQATELWKVLKKYPNQQEHLAHNVAVHASAADAPIQDRVIAYFTKVHPDLGDLIKKEILELSPRK
What is the function of this protein?
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Peroxisomal catalase, PXP-9.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: 3MGH_NITOC
Sequence: MTDLLPPRFYARDALEVAADLLGASLCREQVVLRITEVEAYRWPEDTANHGRHGQTLRNEPLWGPPGRVYLYLCYGIHHLLNLVTGEEGQAAAVLIRACEPVAGLDLIQRRRRGKIKPGLLTGPGKVGAALGLDLSWNHHPLYEPGGLEVRRGTPVAALLAGPRVGIAYAHPEHRDAPWRLAIPDNPWVSCRSQLQPRQQN
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: RIHB_ECOK1
Sequence: MEKRKIILDCDPGHDDAIAIMMAAKHPAIDLLGITIVAGNQTLDKTLINGLNVCQKLEINVPVYAGMPQPIMRQQIVADNIHGETGLDGPVFEPLTRQAENTHAVKYIIDTLMASDGDITLVPVGPLSNIAVAMRMQPAILPKIREIVLMGGAYGTGNFTPSAEFNIFADPEAARVVFTSGVPLVMMGLDLTNQTVCTPDVIARMERAGGPAGELFSDIMNFTLKTQFENYGLAGGPVHDATCIGYLINPDGIKTQEMYVEVDVNSGPCYGRTVCDELGVLGKPANTKVGITIDTDWFWGLVEECVRGYIKTH
What is the function of this protein?
Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively.  Has a clear preference for cytidine over uridine.  Strictly specific for ribonucleosides.
What are the official names of this protein?
Pyrimidine-specific ribonucleoside hydrolase RihB, Cytidine/uridine-specific hydrolase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family. RihB subfamily.
Protein: RLMH_XYLFM
Sequence: MKCLLIATGERVPTWVAQGFAEYHRRLSYWLPLELVEIEPSMRGKNHDPQRAIEDEGRRVMAALPKQPYAVTLDVKGKPLNSEQLAQRMEHWRGLGRNLVFLIGGPEGHSQEVLNISNERWSLGPLTLPHMLVRLIVVEQLYRAATILTNHPYHRGK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TESP1_MOUSE
Sequence: MEASVLSPTSWEKRRAWLRQSRNWQTQVLEEEAAAALQDALDPEPSSLDDVFQEGNPINKIEDWLQGCGCRDTEEGLSEESGQSNYSGYSSHGTSFEDDLSLGAEATLLSTNGNLFSRNFLQTPRLCQLLDLGSSLASSSMTGGTNKTSSSISEILDQVQEDAEDILFSLGFGHENHKDTSRIPARFFSNPSQAKGINFQLFLKSQVQRMEMEDPCLMLASRFKQVQTLAVTADAFFCLYSYVSKTPVQKFTPSNMFWNFDPTDVPSIRILAPEPEPYSPRERLRRAISKMCLYTGSRDRLSSSYNNPKKNSLDQIVWEVMDRVKGEKIQQDPEHRQALGEESVPPIQNTNPSTSSLPCVSYPKEETQGDMCHAHALARPGPQYHINSTQVRRQLWVLQDINEKPRSAENESPWERKSKARKNLFQRVPVDKNIKSLNLPTIQQKQNQGQARHELTNL
What is the function of this protein?
May play a role in the regulation of inositol 1,4,5-trisphosphate receptor-mediated Ca(2+) release and mitochondrial Ca(2+) uptake via the mitochondria-associated endoplasmic reticulum membrane (MAM) compartment (By similarity).  Required for the development and maturation of T-cells, its function being essential for the late stages of thymocyte development.  Plays a role in T-cell antigen receptor (TCR)-mediated activation of the ERK and NFAT signaling pathways, possibly by serving as a scaffolding protein that promotes the assembly of the LAT signalosome in thymocytes.
What are the official names of this protein?
Protein TESPA1, Thymocyte-expressed positive selection-associated protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum membrane. Note=May localize to mitochondria-associated endoplasmic reticulum membrane (MAM).
Protein: UN13C_RAT
Sequence: MVASLFKSLILAYIHKLCKGMFTKKLGNTTKKKENRQQNKDQDFPTAGHTKPPKLSNALKSTVKKIAKCSSTRNFSVEDEEGHKDFSLSPTFSYRVAIANGLQTAVTNSDEDLLQELSSIESSYSESFNELRSSTENQVQSTHTMPVRRNRKSSSSLAPSEGSSDGERTLHTLKLGALRKLRKWKKSQECVSSDSELSTVKKTWGIRSKSLDRTARNPKTNVLEPGFSSSGCISQTHDVMEMIFKELQGISQIETELSELRGHVNALKYSIDEISSSVEVVQSEIEQLRTGFVQARRETRDIHDYIKHLGHMGSKVSLRFLNVPEERHEYVESVVYQILVDKMGFSDVPNAIKIEFAQRIGQQRDCPNAKPRPILVYFETPQQRDSVLKKSYKLKGTGIAISTDILTYDIRERKEKGVLPSSQTYESMDMKLSTPEPKAKKNAWLSPNDSDRELESDLSRSSYADSPAKGSSSKSSSKSHSARSKNKAANSRTSQKSDYNKRPSKPPASEKPTPHYVEATPLWHSQSDFFTPKLSRSESDFSKLCQSYSEDFSESQFFCRTNGSSLLSSSDRELWQRKQEGMTALYHSPQDQGLDGNIPTVPGQGEIENTETVDSGMSNSVVCASGDRSNYSGSQLSLHEDLSPWKEWNQAGHGTDGLDSSTQEPFDYDTNSLSDQQLDMSSKDLDDLGKCHSDLQDDSESYDLTQDDNSSPCPGLDNEPQGQWVGQYDSYQKTNSNDLYPNQSHPSMMYRSQSELQSDDSEAAQPKSWHSRLSIDLSDKTFKFPKFGSTLQRAKSALEVVWNKSTQSLSGCEDSGSSLMGRFRTLSQSTANESSTTLDSDIYTEPYYYKAEEEEDYCEPVADSETDYVEVMEQVLAKLENRTSVTEVDEHIKEYDHPSYETPYETPQDEGYDGQADDIISEGELETLNEPAVEMELVEDESQNLPVEPPEVMKPKRIRPSFKEAALRAYKKQMAELEEKILAGDSSSVDEKARIVSGNDLDASKFSALQVFGGAGRGLYGIDSMPDLRRKKTLPIVRDVAMTLAARKSGLSLAMVIRTSLNNEELKMHVFRKTLQALIYPISSTTPHNFEVWTATTPTYCYECEGLLWGIARQGMKCLECGVKCHEKCQDLLNADCLQRAAEKSSKHGAEDKTQTIITAMKERMKIRERNRPEVFEVIQEMFQISKEDFVQYTKAAKQSVLDGTSKWSAKITITVVSAQGLQAKDKTGSSDPYVTVQVGKNKRRTKTIFGNLNPVWDEKFYFECHNSTDRIKVRVWDEDDDIKSRVKQHFKKESDDFLGQTIVEVRTLSGEMDVWYNLEKRTDKSAVSGAIRLKINVEIKGEEKVAPYHIQYTCLHENLFHYLTEVKSNGSVKIPEVKGDEAWKVFFDDASQEIVDEFAMRYGVESIYQAMTHFSCLSSKYMCPGVPAVMSALLANINAFYAHTTVSTNVQVSASDRFAATNFGREKFIKLLDQLHNSLRIDLSKYRENFPASNSERLQDLKSTVDLLTSITFFRMKVLELQSPPKASAVVKDCVRACLDSTYKYIFDNCHELYSQLIDPSKKQDVPREEQGPTTKNLDFWPQLITLMVTIIDEDKTAYTPVLNQFPQELNMGKISAEIMWSLFALDMKYALEEHEKQRLCKSTDYMNLHFKVKWFYNEYVRELPAFKDAVPEYSLWFEPFVMQWLDENEDVSMEFLHGALGRDKKDGFQQTSDHALFSCSVVDVFAQLNQSFEIIKKLECPNPEALSHLMRRFAKTINKVLVQYAAIVSSDFSSYCDKETVPCILMNNIQQLRVQLEKMFESMGGKELDPEASTILKELQIKLNGVLDALSVTYGESFQLVIEECIKQMGAELNQMRANGNSAANKNNAAMDAEIVLRPLMDFLDKILSLSAKICEKTVLKRVLKELWKLVLNKIEKQIVLPPLTDQTGPQMIFIAAKELGQLSKLKEHMIRDDAKGLTPRQCAIMEVVLATIKQYFHAGGNGLKKNFLEKSPDLHSLRYALSLYTQTTDALIKKFIETQGSQSRSSKDAVGQISVHVDVTTTPGTGEHKVTVKVIAINDLNWQTTTMFRPFVEVCMLGPSLGDKKRKQGTKTKSNTWSPKYNETFQFILGNENRPGAYELHLSVKDYCFAREDRIIGMTVIQLQNIAEKGSYGAWYPLLKNLSMDETGLTILRILSQRTSDDVAKEFVRLKSETRSIDESA
What is the function of this protein?
May play a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway.  May be involved in the regulation of synaptic transmission at parallel fiber - Purkinje cell synapses (By similarity).
What are the official names of this protein?
Protein unc-13 homolog C, Munc13-3.
What is the protein family that this protein belongs to?
Belongs to the unc-13 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein. Presynaptic cell membrane; Peripheral membrane protein. Note=Localized to presynaptic structures.
Protein: AMIF_PHOLL
Sequence: MGSTGSVSAWDEALLIAAIQYPVPIIRGPEDIQVQVQQICKTMDSTKAGYPDLDFIVFPEYSAQGLNTKIWTYDEMLLSLDSPEIDCFRRACIRNDVWGVFSIMERNEDPSQIPYNTAIIINSNGEIVLHYRKLQPWVPIEPWMPGNLGMPVCEGPKGAKLAVCICHDGMFPELAREAAYKGCNVFIRISGYSTQVNDQWIWTNRTNAWQNLMYTVSVNLAGYDEVFYYFGEGTICNYDGNIIQQGQRNPWEIVTAELFPRLADKARENWALENSIFNLGCRGYVGKPGGERANYLTWVRDLANGEYKLPWDENIRIRDGWKYYPEGVKLGPLPKIDE
What is the function of this protein?
Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide.
What are the official names of this protein?
Formamidase, Formamide amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family.
Protein: GERAS_NOSP7
Sequence: MNQLLCPGLYCPFPSQTNKYVDVLEEYSLEWVLRFNLLANESAYKRFCKSKFFFLAASAYPDSKFEELKITHDWLSWVFIWDDQCDLSELKKQPEVLNNFHQRYLEILNGAELTSQDTLFSHALIDLRKRTLQRASIKWFNYFISYLEDYFYGCVQEATNRAKGIVPDLDTYIMIRRSSVGVYAVLALSEFCNQFIIPDVLRNHHLVKKLELITTDIIAWSNDIFSASREIASGDVHNLIFVLHYHKKISLEKAIEQVVKIHNEEVHSLIKVESSLSFFSEELDVEITKYISGMHSWIRGNLDWCYESYRYHNLERLELTEFK
What is the function of this protein?
Catalyzes the cyclization of farnesyl diphosphate (FPP) to the sesquiterpene germacrene A.
What are the official names of this protein?
Germacrene A synthase, 5-epi-alpha-selinene synthase, 8a-epi-alpha-selinene synthase, Terpene synthase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: RL15_MICLU
Sequence: MADNDAIKVHDLRPAPGAKTAKTRVGRGEASKGKTAGRGTKGTKARYQVRAGFEGGQLPLQMRLPKLRGFKNPFRTEYQVVNLDKLSAHFPEGGEVTVDALVSKGLVRRGQPVKVLGTGEITAAVQVKANAFSASAVEKIQAAGGSTETL
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: SYA_CHRVO
Sequence: MKTSEIRKKFLDFFASKGHQVVPSSSLIPGNDPTLMFTVAGMVQFKDVFLGFEKRDYTRATTSQKCLRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKRDAITFAWEFLTGEQWLALPKDKLMVTVYATDDEAYDIWHQTVGLPADKIVRIGDNKGAPYASDNFWTMGDTGPCGPCTEIFFDHGPSVAGGPPGSPDEDGDRFMEIWNNVFMQFNRDEAGTLHPLPKPSVDTGMGLERLSTVLQHVKSNYETDALACLVRAAARETGVEYSQDVPSLKVIADHIRACSFMVADGILPSNEGRGYVLRRIARRAIRHGYKLGQKGLFFHKIVADLVAEMGEAYPELREKQAHIEDALRAEEIKFAETLEIGMGLVDSALEGGKTALDGDTIFKLYDTFGFPVDLTADICRERGIHADLEGFERAMEAQRERGRAGSNFKMSGKIAYDGEDTRFHGYDKSSVEAKVLALYKGTDPVDSLSAGDEGIVVLDGTAFYAEGGGQVGDVGEISAAGGIAALFDVADTQKIQGAAFGHKGKLARGALKVGDAVTATIDLHQRQASARNHSATHLLHAALRHVLGGHVVQKGSLVNPERTRFDFAHGEAVTAAQIAELERVVNHVIAANYEVKAELMSMEAAQKSGAMMLFGEKYGDEVRVLTMGDFSAELCGGTHVKRTGDIGLFKIVAEGGVAAGVRRIEAVTGEGALAYIQAQDALIKEAAAALKAQTSDEVLAKIAALQDSAKALEKELAKLKGQLASSAGDSLADAAADINGVKVLAAELPGADNTALRETLDKLKDKLGSAAIVLAAKGDGKVALVAGVTADLTGKLKAGELVNFVAQQVGGKGGGRPDMAQAGGTQPENLDAALNGVQAWVAGKL
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS21_MOUSE
Sequence: MQNDAGEFVDLYVPRKCSASNRIIAAKDHASIQMNVAEVDRTTGRFNGQFKTYGICGAIRRMGESDDSILRLAKADGIVSKNF
What is the function of this protein?
Component of the small ribosomal subunit (PubMed:36517592).  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:36517592).
What are the official names of this protein?
40S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS21 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Rough endoplasmic reticulum. Note=Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).
Protein: IDI_LEIXX
Sequence: MTPPREEVVLLAEDGAPIGTADKATVHSESTPLHLAFSCHLFDGDGRILVTRRALGKATWPGVWTNSFCGHPALGESLEEAIARRAHEELGTSVDALALALALPDFRYRAVDATGVVEHEMCPVYTATIAWELRPSADEVAEWEWADPRALLSSVAATPWAFSPWLTLQLPALYAASGDQPSGQL
What is the function of this protein?
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate Delta-isomerase, IPP isomerase, IPP:DMAPP isomerase, Isopentenyl pyrophosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VF183_ASFK5
Sequence: MSVVVGGVEYSLNNWAKYEIKRRAAELESVNYYPRCEYIMPEDIVVSILGSKPNCPFLEALKRFHDFLNKRRIIFKEGYLVIPWMGAQDVADMIHHVENRINLGHLEDLAHMLKLITYHKSLDTSINQSFENLYAFKFPDANIETHELKLIRQLEKKMYGYILRLEKLQTMLTFYIEFLLKQV
What are the official names of this protein?
Uncharacterized protein S183L, pS183L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus S183L family.