PharMolix/UniProtQA huggingface dataset:
Protein: KDUI_CERS1
Sequence: MTHVEIRHAMDPVSARQLDTAGLREAFHMGDLFRSGEIRLVYTHYDRMIVGGAVPAGEPLVLDEVKPTGTASILDRREMGVVNVGAAGTVSAGGESWEMGRGDVLYLPMGAGPVTFAGEGRFYILSAPAHTAHPARLVKLEDAKKVKLGSPETANERTINQFIHPEVMQSCQLVVGYTQFHGGSVWNTMPAHVHDRRMEAYLYFDLAEEARVFHFMGEPSETRHLVMRNEEAVVSPPWSIHCGCGTGSYTFVWAMAGDNVDYRDVEMVAMEDLR
What is the function of this protein?
Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.
What are the official names of this protein?
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase, 5-keto-4-deoxyuronate isomerase, DKI isomerase.
What is the protein family that this protein belongs to?
Belongs to the KduI family.
Protein: PAN2_NEUCR
Sequence: MDSRDWTQLGCVAYPSPIHPDYHAGPASTIAFDNQDELLWIGTQKGFAGSFIGRELKRFTAFRIHPETDGPLRQFLFVDKGVIFLGSRSVYMAARSGVPIWSIRHESMQDLRAMSFTSKGTSEILVAGWQNKMLVIDVNKGEVVKELPTQDQYSFLKMSRYICAATNKGTVNILDPITFTIKKQWQAHGAFINDLDTSNDFIVTCGGSHRQTHNTPAILDPYVKVFDLKNMSAMNPVPFAPLAAHVRMHPRMLTTAIVVNQAGQIHVTDLLNPSNSQVCYTQPQGVVLHFDVSRTGEGKALADNKHNTYVWGSPNKIQFTEIGIPPRLPDPPQPSLLPPDPDMLEELPLSRIGLPYYREQLFSALPPDIISDVGAPPQQIDPNILSTLTKTDWGYIGPNKTGLQRNQYMDTRSTMKTSNTIRAPKFLSEKARESQTGSEDNTLATNETAMMTPNNDHWSLRPEAPPEYRICEIKYSKFGVDDFDFGFFNNTPYPGLENNITNSYANSLLQVMHYTPLLRNMALQHAATACLADPCLLCELGYVFDMLQKGEGPSCHATNMLRALNHTSNASVSGVLEDIAKDKNPSTLVKNLTMFLFDKISQDYKGTPPISTELERTLFKLNQPPNPLDLVKRLLETDARYQIKCMHCQHVSPRTATTFVNKLCYPAAKPNIRGMKAQRITFSQVLKAGLENEAVNKGYCTKCQRYQNLDQRKIIFNIPAVLALCTEITTAEHRKLWSTPGWLPEEIGIIVDQGHVYCYEGDDLKLHLNRGIHNITVYSLVGTVVNVETKSPQKSHLVATVNVGRAEPESKDQDRWHLFNDFSVRGISKVEALTFNAAWKMPVVVMFQVKAANHRFNMDWKTRLDTSVLFRDNNPHALKTYELLDRETEIPGPDTVIAIDTEFIRLKEREIHIDEDGKSKTIRPISHAIARASVVRGQGSREGVAFIDDYIHIKETIVDYLTEWSGITPTDLDPINSQRNLVSPKTAYKKLWVLVNLGCKFLGHGLSQDFRVINIQVPRNQVIDTSIIFMKPPSQRKISLAFLAWYLLKEDIQQNTHDSIEDAQTALKLYRKYEEFMANGSFHDVLEALYKKGKTLNFKPPRISTGAAKDAGFGAVHRVGTPPVPAPGTTEGSFEISNSSTATTGGSALSATGGMGSASASSSMPSTPVRKPIGLGGPFTVAGVVKPSPATSLDNFGAGAVGTGITTAAATMGGGYGGYGTDGAYWGGPNDMAPTSMIGGSAFIPAKFPPGPPETRGFIPYRPQVLLAEREAAAAAAAAAAAAAANNDVGGRGGVACGNGGAGGEQGKQE
What is the function of this protein?
Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover.  PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein pabp-1.  PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex.  Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by rgb-30/xrn1.  May also be involved in post-transcriptional maturation of mRNA poly(A) tails.
What are the official names of this protein?
PAN2-PAN3 deadenylation complex catalytic subunit pan2, PAB1P-dependent poly(A)-specific ribonuclease, Poly(A)-nuclease deadenylation complex subunit 2, PAN deadenylation complex subunit 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. PAN2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y873_MYCTU
Sequence: MAQQTQVTEEQARALAEESRESGWDKPSFAKELFLGRFPLGLIHPFPKPSDAEEARTEAFLVKLREFLDTVDGSVIERAAQIPDEYVKGLAELGCFGLKIPSEYGGLNMSQVAYNRVLMMVTTVHSSLGALLSAHQSIGVPEPLKLAGTAEQKRRFLPRCAAGAISAFLLTEPDVGSDPARMASTATPIDDGQAYELEGVKLWTTNGVVADLLVVMARVPRSEGHRGGISAFVVEADSPGITVERRNKFMGLRGIENGVTRLHRVRVPKDNLIGREGDGLKIALTTLNAGRLSLPAIATGVAKQALKIAREWSVERVQWGKPVGQHEAVASKISFIAATNYALDAVVELSSQMADEGRNDIRIEAALAKLWSSEMACLVGDELLQIRGGRGYETAESLAARGERAVPVEQMVRDLRINRIFEGSSEIMRLLIAREAVDAHLTAAGDLANPKADLRQKAAAAAGASGFYAKWLPKLVFGEGQLPTTYREFGALATHLRFVERSSRKLARNTFYGMARWQASLEKKQGFLGRIVDIGAELFAISAACVRAEAQRTADPVEGEQAYELAEAFCQQATLRVEALFDALWSNTDSIDVRLANDVLEGRYTWLEQGILDQSEGTGPWIASWEPGPSTEANLARRFLTVSPSSEAKL
What are the official names of this protein?
Probable acyl-CoA dehydrogenase FadE10.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
Protein: DBP2_YEAST
Sequence: MTYGGRDQQYNKTNYKSRGGDFRGGRNSDRNSYNDRPQGGNYRGGFGGRSNYNQPQELIKPNWDEELPKLPTFEKNFYVEHESVRDRSDSEIAQFRKENEMTISGHDIPKPITTFDEAGFPDYVLNEVKAEGFDKPTGIQCQGWPMALSGRDMVGIAATGSGKTLSYCLPGIVHINAQPLLAPGDGPIVLVLAPTRELAVQIQTECSKFGHSSRIRNTCVYGGVPKSQQIRDLSRGSEIVIATPGRLIDMLEIGKTNLKRVTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVKQLAADYLNDPIQVQVGSLELSASHNITQIVEVVSDFEKRDRLNKYLETASQDNEYKTLIFASTKRMCDDITKYLREDGWPALAIHGDKDQRERDWVLQEFRNGRSPIMVATDVAARGIDVKGINYVINYDMPGNIEDYVHRIGRTGRAGATGTAISFFTEQNKGLGAKLISIMREANQNIPPELLKYDRRSYGGGHPRYGGGRGGRGGYGRRGGYGGGRGGYGGNRQRDGGWGNRGRSNY
What is the function of this protein?
ATP-dependent RNA helicase involved nonsense-mediated mRNA decay and ribosome biogenesis through rRNA processing (PubMed:11585918, PubMed:7883168).  Associates directly with chromatin, correlating with transcriptional activity (PubMed:22679025).  Required for assembly of mRNA-binding proteins YRA1, NAB2, and MEX67 onto poly(A)+ RNA (PubMed:23721653).
What are the official names of this protein?
ATP-dependent RNA helicase DBP2, DEAD box protein 2, p68-like protein.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RR2_CHAGL
Sequence: MNSWNINLEDMMEAGVYLGHQARKWNPKMAPYIFAERKGIHIINLTQTARFLTEACDLLFNTAKNGEQFLIVGTKYQAADLVALTAKKSRCHYVNQKWLGGMLTNWTTIKKRLKKLQELESLESINGFDRFPKKEASNLKRQLAQLRKYLGGIRHMTKLPDIVIIIDQQHELTALKECLILGIPTICFVDTDCDPDLTDIPIPANDDSRASIQWILNKLTNSIREGRAFSKNDSIN
What are the official names of this protein?
30S ribosomal protein S2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: EMRB_MYCTU
Sequence: MLGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVTVVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTLGSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGPVGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPGLATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVAQANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRRGPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTLAPHQIARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAAVDPSSLPRQTNFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQASHRRAPLLSA
What are the official names of this protein?
Multidrug resistance protein B homolog.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. EmrB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GLMM_STRAW
Sequence: MGRLFGTDGVRGVANADLTAELALGLSVAAAHVLAEAGTFEGHRPVAVVGRDPRASGEFLEAAVVAGLASAGVDVLLVGVLPTPAVAHLTGALGADLGVMLSASHNAMPDNGIKFFARGGHKLADDLEDRIEAVYEEHRTGAPWDRPTGAGVGRVTSYGEGADQYVAHLMSVLPNRLDGIKVVLDEAHGAAARVSPDAFTRAGAEIITIGAEPDGLNINDGCGSTHLAKLRAAVVEHGADLGIAHDGDADRCLAVDHTGAEVDGDQILAVLALAMRERSALRSDTVVATVMSNLGFKLAMEREGLSFVQTAVGDRYVLEEMKEHGYALGGEQSGHVIILDHATTGDGTLTGLLLAARVAQTGRTLQDLASVMERLPQVLVNVPDVDRARVKTSAELATAVAEAERELGATGRVLLRPSGTEPLVRVMVEAADIEQARSVAGRLADAVKSALG
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: DSBI_ECOK1
Sequence: MGIKGMWKDLRTSPVDTLVRWQEQRLLWLLMAVAMGALIILAHSFFQIYLYMAPCEQCVYIRYAMFVMVIGGLVAAINPKNIILKLIGCVMAFYGSILGLKFSLKLNDIHHAVHNPDPDSLFGVQGCSTDPTFPFNLPLAQWAPNWFKPTGDCGYDAPIVPDGVTLSSTQQWFVEMYQQSEGWYLLPPWHFMNMAQACMLAFGMCLVLLVIMSGAWALKIIRG
What is the function of this protein?
Required for disulfide bond formation in some proteins.  Part of a redox system composed of DsbI and DsbL that mediates formation of an essential disulfide bond in AssT.
What are the official names of this protein?
Protein-disulfide oxidoreductase DsbI.
What is the protein family that this protein belongs to?
Belongs to the DsbB family. DsbI subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FABZ_ROSS1
Sequence: MLTIQEIMAIIPHRYPFLLIDRILELEPGQRAVGEKLVTIGEPYFQGHFPNRPIMPGVLIVEALAQTGAVAALSLPENRGKMAFFAGIDGVRFRKPVYPGDTLRLEVRFDKMRRGIGKGTGVATVNGQLVCEGELMFALSSEG
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GVPA_KORVE
Sequence: MAVERVSGGSSLIDVLDRVLDKGIVIDAWVRISLVGIDLITVEARVVVASIDTYLKYADAVGLTGLVSRPQLTEVVEEPVVVEAPATRRTARPSRRRI
What is the function of this protein?
Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms.  They allow the positioning of the organism at the favorable depth for growth.  GvpA type proteins form the essential core of the structure.
What are the official names of this protein?
Gas vesicle structural protein, GVP.
What is the protein family that this protein belongs to?
Belongs to the gas vesicle protein type A family.
What are the subcellular locations of this protein?
Vacuole, gas vesicle membrane.
Protein: RIMO_ELUMP
Sequence: MAKIFTISLGCSKNLTDTEEMLGILNHKKHYLVADESEADTILINTCAFIKPAREEADREIKRASKLKAQGKIEKLIVAGCLTQKEGKSLPSKYPLVDAFIGLKGIEKIDNVIKRPKHSFCPAPDYIKAPDFKLQLTAPHSAYLKVADGCNNRCAYCTIPAIRGPFRSKSMEDIVAEAKAMEKNGVKEISLIAQDTTAYGQDIFGKPSLVKLLKKLVKIKGIEWFRIMYAYPETVTKDLLDFIACEPKICRYLDMPLQHISAPVLKAMNRRSTEDEVRAKIKLIRQIVPGMSLRTNFIAGFPGETAEDFEKLKKFIAEAKFNNVGVFAYSKEDGTPAAVMKRQVAEKIKKQRVEELVSAQSRVIDSINRKLKGKTVKVLLDNLFCGRSESDSPDIDGRVEVKGNKKYKAGDFVKVKITSAKGYNRTGKII
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSD_SYMTH
Sequence: MSDMRRPIIAREGWPFVGALVALAVLALFVHWALGAVLAGLALFVMWFFRDPERPIPREDGLVVSPADGRVMFVREVEEPRFVGGRALLVSIFLSVFDVHINRSPVAGEVTYREYVPGKFLAAWDDTVGEVNERAYLGLVTDGGHRVLVSQVAGLLARRIVTWPAVGDRLDRGQRFGLIRFGSCTQVWLPADSEVLVRPGDRVVAGQTVIGRLPQ
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: Y5174_BACCR
Sequence: MEQTLVIQKKKGFGFSQGIGITLLIAIAAKYLAELPFLNIMGQLVIAILIGMVWRAAIGVPHDAIAGTNFASKKLLRFGIILLGMRLNLVDIAKAGPKVLVIAAVVITFTIFVVYGLTKVFKVEKKLGILTACGTAICGAAAVVAIAPQVKAKDDETAVGAAIIAILGTIFTLIYTLLYPVLGLSPYGYGVFSGATLHEIAHVIAAAAPGGSTAVDIAVIVKLTRVAMLVPVAILIGLWFGKSEGSEGKRSWRELPIPWFIFGFLAMSAVHSLGIIPEVVAGYIVVLAYMLIAMAMAGLGLNVEFKTFRKLGSKAFVAGLIGSVCLSVLGYVLVYALGFM
What are the official names of this protein?
UPF0324 membrane protein BC_5174.
What is the protein family that this protein belongs to?
Belongs to the UPF0324 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TAF13_ARATH
Sequence: MSNTPAAAASSSSKSKAAGTSQPQEKRKTLFQKELQHMMYGFGDEQNPLPESVALVEDIVVEYVTDLTHKAQEIGSKRGRLLVDDFLYLIRKDLPKLNRCRELLAMQEELKQARKAFDVDEKELVD
What is the function of this protein?
TAFs are components of the transcription factor IID (TFIID) complex that is essential for mediating regulation of RNA polymerase transcription.  May be involved in polycomb repressive complex 2 (PRC2) mediated repression.
What are the official names of this protein?
Transcription initiation factor TFIID subunit 13, TBP-associated factor 13, AtTAF13.
What is the protein family that this protein belongs to?
Belongs to the TAF13 family.
What are the subcellular locations of this protein?
Nucleus. Cell membrane. Note=At the torpedo stage, localized both in the nucleus and at the plasma membrane.
Protein: MALT_ECO27
Sequence: MLIPSKLSRPVRLDHTVVRERLLAKLSGANNFRLALITSPAGYGKTTLISQWAAGKNDIGWYSLDEGDNQQERFASYLIAAMQQATNGHCAICETMAQKRQYASLTSLFAQLFIELAEWHSPLYLVIDDYHLITNPVIHESMRFFIRHQPENLTLVVLSRNLPQLGIANLRVRDQLLEIGSQQLAFTHQEAKQFFDCRLSSPIEAAESSRICDDVSGWATALQLIALSARQNTHSAHKSARRLAGINASHLSDYLVDEVLDNVDLATRHFLLKSAILRSMNDALINRVTGEENGQMRLEEIERQGLFLQRMDDTGEWFCYHPLFGNFLRQRCQWELAAELPEIHRAAAESWMAQGFPSEAIHHALAAGDALMLRDILLNHAWSLFNHSELSLLEESLKALPWDSLLENPQLVLLQAWLMQSQHRYGEVNTLLARAEHEIKDIREGTMHAEFNALRAQVAINDGNPDEAERLAKLALEELPPGWFYSRIVATSVLGEVLHCKGELTRSLALMQQTEQMARQHDVWHYALWSLIQQSEILFAQGFLQTAWETQEKAFQLINEQHLEQLPMHEFLVRIRAQLLWAWARLDEAEASARSGIEVLSSYQPQQQLQCLAMLIQCSLARGDLDNARSQLNRLENLLGNGKYHSDWISNANKVRVIYWQMTGDKAAAANWLRHTAKPEFANNHFLQGQWRNIARAQILLGEFEPAEIVLEELNENARSLRLMSDLNRNLLLLNQLYWQAGRKSDAQRVLLDALKLANRTGFISHFVIEGEAMAQQLRQLIQLNTLPELEQHRAQRILREINQHHRHKFAHFDENFVERLLNHPEVPELIRTSPLTQREWQVLGLIYSGYSNEQIAGELEVAATTIKTHIRNLYQKLGVAHRQAAVQHAQKLLKMMGYGV
What is the function of this protein?
Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides.  Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.
What are the official names of this protein?
HTH-type transcriptional regulator MalT, ATP-dependent transcriptional activator MalT.
What is the protein family that this protein belongs to?
Belongs to the MalT family.
Protein: HSP76_PIG
Sequence: MSAAREVAIGIDLGTTYSCVGVFQHGRVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQAALNPQNTVFDAKRLIGRKFADPTVQSDLKHWPFQVVSEGGKPKVRVSYRGEDKAFYPEEISSMVLSKMKETAEAYLGQPVRHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDRRGAGERNVLIFDLGGGTFDVSVLTIDAGVFEVKATAGDTHLGGEDFDNRLVNHFMEEFRRKHRKDLSRNKRALRRLRTACERAKRTLSSSTQATLEIDSLFEGVDFYTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDIVLVGGSTRIPKIQKLLQDFFNGRELNKSINPDEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAPLSLGLETAGGVMTTLIQRNATIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILSVTATDRSTGRANKITITNDKGRLSKEEVERMVREADEYKVEDEAQRDRVAAKNSLEAYVFHVKGSLHEESLRDKIPEEDRCKVQDKCQEVLTWLEHNQLAEKEEYEHQKRELEQICRPIFSRLYGAPGIPGGSSCGAQARQGAPSTGPVIEEVD
What is the function of this protein?
Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes.  Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation.  This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones.  The affinity for polypeptides is regulated by its nucleotide bound state.  In the ATP-bound form, it has a low affinity for substrate proteins.  However, upon hydrolysis of the ATP to ADP, it undergoes a conformational change that increases its affinity for substrate proteins.  It goes through repeated cycles of ATP hydrolysis and nucleotide exchange, which permits cycles of substrate binding and release.
What are the official names of this protein?
Heat shock 70 kDa protein 6, Heat shock 70 kDa protein B'.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: PURA_VIBVY
Sequence: MANNVVVLGTQWGDEGKGKIVDLLTEDAKYVVRYQGGHNAGHTLVIDGVKTVLHLIPSGILRDNVKCVIGNGVVLSPEALIKEMKPLEERGIPVRERLFISEACPLILPYHVAMDQAREIARGKKAIGTTGRGIGPAYEDKVARRGLRVGDLFDMEAFAEKLKEVMEFHNFQLVNFYKAEAVSYEEVLEQAKGYAELLTSMVIDVTDELDAARKRGDKIMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVAAGSGFGPRYLGYILGIAKAYCTRVGAGPFPTELYDGQEKQDPVGKHLGTVGHEFGATTGRLRRTGWFDAVAMRRAIQINSVSGFCLTKLDVLDGLKELKICTGYQMEDGSVLEVSPMAAEAFEKVTPIYETMPGWSENTFGAKSLEDLPQAAINYIKRIEELTGVPVDIISTGPDRNETIVKVHPFES
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4601_AGRFC
Sequence: MGNHAMLLEKHTAVRKGRLHDGKVMVMRSNLRWCSDGLEFACWNGEVIRLAFIIDAFDREIIAWTAVANAGISGSDVRDMMLEAVEKRFHATRAPHAIEHLSDNGSAYTARDTRLFAQALNLTPCFTPVASPQSNGMSEAFVKTLKRDYIRISALPDAQTALRLIDGWIEDYNEIHPHSALKMASPRQFIRAKSI
What are the official names of this protein?
Insertion element IS136 uncharacterized protein Atu4601.
Protein: AL1A3_HUMAN
Sequence: MATANGAVENGQPDRKPPALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLGDKNP
What is the function of this protein?
NAD-dependent aldehyde dehydrogenase that catalyzes the formation of retinoic acid (PubMed:27759097).  Has high activity with all-trans retinal, and has much lower in vitro activity with acetaldehyde (PubMed:27759097).  Required for the biosynthesis of normal levels of retinoic acid in the embryonic ocular and nasal regions; retinoic acid is required for normal embryonic development of the eye and the nasal region (By similarity).
What are the official names of this protein?
Aldehyde dehydrogenase family 1 member A3, Aldehyde dehydrogenase 6, Retinaldehyde dehydrogenase 3, RALDH-3, RalDH3.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLO2_ECO8A
Sequence: MNLNSIPAFDDNYIWVLNDEAGRCLIVDPGDAEPVLNAITANNWQPEAIFLTHHHHDHVGGVKELVEKFPQIVVYGPQETQDKGTTQVVKDGETAFVLGHEFSVIATPGHTLGHICYFSKPYLFCGDTLFSGGCGRLFEGTASQMYQSLNKLSALPDDTLVCCAHEYTLSNMKFALSILPHDLSINDYYRKVKELRAKNQITLPVILKNERQINVFLRTEDIDLINVINEETLLQQPEERFAWLRSKKDRF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: MLR_DROME
Sequence: MADEKKKVKKKKTKEEGGTSETASEAASEAATPAPAATPAPAASATGSKRASGGSRGSRKSKRAGSSVFSVFSQKQIAEFKEAFQLMDADKDGIIGKNDLRAAFDSVGKIANDKELDAMLGEASGPINFTQLLTLFANRMATSGANDEDEVVIAAFKTFDNDGLIDGDKFREMLMNFGDKFTMKEVDDAYDQMVIDDKNQIDTAALIEMLTGKGEEEEEEAA
What are the official names of this protein?
Myosin regulatory light chain 2, MLC-2.
Protein: CBPN_HUMAN
Sequence: MSDLLSVFLHLLLLFKLVAPVTFRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEVKYVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQGPNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPNHHLPLPDNWKSQVEPETRAVIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTASTPTPDDKLFQKLAKVYSYAHGWMFQGWNCGDYFPDGITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKFPPEEELQREWLGNREALIQFLEQVHQGIKGMVLDENYNNLANAVISVSGINHDVTSGDHGDYFRLLLPGIYTVSATAPGYDPETVTVTVGPAEPTLVNFHLKRSIPQVSPVRRAPSRRHGVRAKVQPQARKKEMEMRQLQRGPA
What is the function of this protein?
Protects the body from potent vasoactive and inflammatory peptides containing C-terminal Arg or Lys (such as kinins or anaphylatoxins) which are released into the circulation.
What are the official names of this protein?
Carboxypeptidase N catalytic chain, CPN, Anaphylatoxin inactivator, Arginine carboxypeptidase, Carboxypeptidase N polypeptide 1, Carboxypeptidase N small subunit, Kininase-1, Lysine carboxypeptidase, Plasma carboxypeptidase B, Serum carboxypeptidase N, SCPN.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: FLIW_LEPBJ
Sequence: MEIEIQTKPFGKMQISEKQILSFPEGLLGFEDYKKFALIEEEEESVFKWLQSVEEVDLAFVVIPPSLFKKEYKPLISEQELQGIGITDLEDGLMLVIVTVPGEDPALMTANMQGPILINKKTLLGKQFISRNESHSVREKILASAAVEMD
What is the function of this protein?
Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin.  Binds to flagellin and participates in the assembly of the flagellum.
What are the official names of this protein?
Flagellar assembly factor FliW.
What is the protein family that this protein belongs to?
Belongs to the FliW family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPG_AGGAC
Sequence: MSTNQETRGFQSEVKQLLQLMIHSLYSNKEIFLRELISNASDAADKLRFKALSNPDLYAGDGELRVCISFDSEKGTLTVSDNGIGMTREQVIDHLGTIAKSGTKEFLAALGSDQAKDSQLIGQFGVGFYSAFIVADKVTVKTRAAGEPADKGVLWESAGEGDYTVADIEKKSRGTDVILHLRDDEKEFLNEWRLRGIIGKYSDHIGLPVEMLTKEYEDEGKEIGEKWEKINKSDALWTRSKNEISDEEYKEFYKHLSHDFADPLLWAHNKVEGNQEYTSLLYVPSKAPWDLFNREHKHGLKLYVQRVFIMDDAEQFMPNYLRFMRGLIDSNDLPLNVSREILQDNKVTAALRKALTKRSLQMLEKLAKDDAEKYQQFWKEFGLVLKEGPAEDFANKEAIAKLLRFASTHNDSSEQNVSLEDYVSRMKEGQKAIYYITADSYVAARNSPHLELFNKKGIEVLLLSDRIDEWMLSYLTEFDGKPLQSITKADLDLGDLADKEAEEQKAQDESFGSFVERVKTLLGGRVKEVRLTHRLTDTPAVVSTDNDQMTTQMAKLFAAAGQPVPEVKYTFELNPEHHLVKKVAEIADEAQFADWVELLLEQAMLAERGSLENPAAFIKRINKLLG
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.