PharMolix/UniProtQA huggingface dataset:
Protein: CD5R1_CAEEL
Sequence: MGANLTSPLPHHHRTQTTSVCNHLFSPGDGGPTFAPQRDSNTSSRSSSNAKESVLMQGWNWSKRNIQPVMSRRSLPKSGSSSEATSSKSSDSLVSFTRNVSTSTSSQYGKISISLDRNQNYKSVPRPSDTTTIIPNYYSLREEFRRGLQINTRQDLVNNNLASNDLSVIGSPKHVPRPRSVLRDDNANCDISPIAEQENVPSEASTSELLRGLGIFISNNCDVSDFDPAHLVTWLRSVDRSLLLQGWQDIAFINPANLVFIFLLVRDVLPDERHLIHTLEELHAWILSCLYVSYSYMGNEISYPLKPFLIGNDRNTFWNRCVAMVTSHSRQMLLLNSSSTFFSEVFTDLKHCSSSE
What is the function of this protein?
Activator of the kinase cdk-5 (By similarity).  In several motor neurons, promotes the polarized trafficking of synaptic vesicles and dense-core vesicles.  In the ventral nerve cord, regulates the synaptic localization of the glutamate receptor, glr-1 (PubMed:17671168).  In DA motor neurons, regulates axonal transport of synaptic vesicle precursors by inhibiting dynein-mediated retrograde transport (PubMed:20510931).  Regulates the polarized distribution of dense-core vesicles in DB motor neurons (PubMed:22699897).  May regulate these processes in association with cdk-5 (PubMed:17671168, PubMed:20510931).  May also play a role in GABAergic synaptic vesicle localization in the ventral nerve cord (PubMed:16996038).
What are the official names of this protein?
Cyclin-dependent kinase 5 activator 1, p35.
What is the protein family that this protein belongs to?
Belongs to the cyclin-dependent kinase 5 activator family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, dendrite. Cell projection, axon. Note=Presynaptic localization in the axon and punctate localization in the dendrite.
Protein: DDX49_DICDI
Sequence: MSDKTFEELGLTTWLVANCKQLGFKAPSNIQANTIPEILKGRDIIASAKTGSGKTASFAIPILNQLSEDPYGVFAVILTPTRELAVQIGEQFNAIGAPMNVNCSVVIGGIDNVTQALILDKRPHIIVATPGRLASHLNNGLKIALKFCKFLVLDEADRLLGEDFELEIASILEHLPPPEKRQTLLFSATMTKNLTKLDSIALNKPFIFEDNSKYDTVDTLKQEYIYMPAPTKDCYLVYILKKHEGSSAIVFVNNCYAVEAVKGMLNKLDIPSVSLHSFLDQKSRLAALKTFKSGKVKVLVATDVASRGLDIPDVQIVINYKLSNSSKDYIHRVGRTARFGRSGRAISFITPHDVSLIKGIEEIIKKQLELYKTDDDEVFRHLKEASTARKIVEIHLDEIEFGVKQKERRTERNELQKQLKEVNNKEKFENNNNDNNNNNKTKTTKPENKKEITKIQEQPSKSTTTTKSIEKKPTTIESKKIDKDIKRKENNFDDGEISLFKKKKITNK
What is the function of this protein?
Probable ATP-binding RNA helicase.
What are the official names of this protein?
Probable ATP-dependent RNA helicase ddx49, DEAD box protein 49.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily.
Protein: RIMK_XYLF2
Sequence: MKLAILSRNSKLYSTRRLVEVARMRGHTVRILDPLRCYMRIVVGDFSMHYKGKPIDGYHAVIPRIGVSVTHYAAAVLRQFELMGTYSPNPSDAILRSRDKLRAHQLLAAQGIDMPMTVFGDNPDDTQDLLSMLGPPPHVVKLNEGAQGKGVILSEKNSASRGLVEALRGLYANFLVQEFISEADSADLRCFVVGNQVVATMRRQAAEGDFRSNLHLGGSATAATASEEEQEVAVRSAHALGLTVAGVDLIRSRRGPLVLEVNPTPGLEGIEATSGTNVAIKIVRHVEEMLATICSSNICKP
What are the official names of this protein?
Probable alpha-L-glutamate ligase.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: RG84C_DROME
Sequence: MISGSGSRTPSNRLYLSPVRPTMQNKRRLLREYRSYDDLSEHYRMFGSQSLDSLQDRVDMNPSGCDGLSTDGLDFCSQSHSGLLREHNFKIKSYYYNVGNCVHCRKRIRFAMASLRCRACPLRCHIGCCRQLTVNCIPQPQIGTKRGCLSDYAPRVAPMVPALIVHCVTEIEARGLQQEGLYRVSSTREKCKRLRRKLLRGKSTPHLGNKDTHTLCCCVKDFLRQLVHPLIPIYHRRDFEEATRHEDRLAVEMAVYLAVLELHQAHRDTLAYLMLHWQKIAESPAVRMTVNNLAVIFAPTLFGDLDLTLENVVTWQRVLKVLLLMPAGFWSQFLEVHPLPTSLGSTYDFEDRYNHRHWDSSSNLGWSSVKTYFRSMVNLSSTHL
What is the function of this protein?
Involved in the morphogenesis of the adult appendages.  GTPase-activating protein for p21-Rac.  Promotes the exchange of Rac-bound GDP by GTP.
What are the official names of this protein?
GTPase-activating protein RacGAP84C, Protein rotund RacGAP.
Protein: TRPF_PSEA7
Sequence: MPAVRIKICGITRVEDALAAAAAGADAIGLVFYAKSPRAVNIHRAREIVRALPPFVTSVGLFVNASRCELGEILDAVPLDLLQFHGDERAEDCEGHRRPYLKALRMKPGDDILARVADYPGAAGILLDTYVEGVPGGTGAAFDWSLVPAGLGKPLVLAGGLTANNVADAVARVQPYAVDVSGGVEASKGIKDAAKVRAFVDAVRSRGRDEA
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: UXP_ADES1
Sequence: MTEVRLNNQTLVRLEAPTPSWKWIKLSRTLKLKMLNLPGVKIFRGAPENEDQDRDNLM
What are the official names of this protein?
Probable U-exon protein.
Protein: AROA_STRE4
Sequence: MKLKTKAKALRGRLRVPGDKSISHRAVIFGAIAEGQTVIHGLLRGQDVLATIQAFRDLGVTIYESADSLIIEGRGFKGLKPAQKPLDMGNSGTSMRLLAGLLAAQDFSVQLLGDDSLSRRPMDRITIPLSLMGAELSGQGEKELPPLIVKGCQELRPIHYQLPVASAQVKSAILLAALQTQGETVILEKELTRNHTEEMIEQFGGKLSVAGKQISIKGPQRLQGQTLQIPGDLSSAAFWLAAGLIVPGSDLVLENVGINPTRTGLLEVIEKMGGRISYQAVDKDRQAATLKVSYSTLKGIEISGDLIPRLIDELPVIALLATQAQGTTYIRDAQELRVKETDRIQAVTDVLGQMGADIQATEDGMVTRGKTPLHGAAVSTCGDHRIGMMTAIAALLVEEGQVTLERAEAILTSYPDFFKDLERLWHD
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS21_AGRLI
Sequence: MENDAGEFVDLYCPRKCSASNRIIHAKDHASIQLSIAEVVPATGRMTENTKSYALCGAIRRMGESDDCIVRLTKKDGILTKNF
What are the official names of this protein?
40S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS21 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Rough endoplasmic reticulum. Note=Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).
Protein: EXPA4_ARATH
Sequence: MAIKLAILFTTFVLFSLADARIPGIYSGGAWQNAHATFYGGSDASGTMGGACGYGNLYSQGYGTNTAALSTALFNNGMSCGACFELKCANDPQWCHSGSPSILITATNFCPPNLAQPSDNGGWCNPPREHFDLAMPVFLKIAQYRAGIVPVSYRRVPCRKRGGIRFTINGHRYFNLVLITNVAGAGDIVRASVKGSRTGWMSLSRNWGQNWQSNAVLVGQALSFRVTGSDRRTSTSWNMVPSNWQFGQTFVGKNFRV
What is the function of this protein?
Causes loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans.  No enzymatic activity has been found (By similarity).
What are the official names of this protein?
Expansin-A4, AtEXPA4, Alpha-expansin-4, At-EXP4, AtEx4, Ath-ExpAlpha-1.6.
What is the protein family that this protein belongs to?
Belongs to the expansin family. Expansin A subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Peripheral membrane protein.
Protein: RS3_RHIWR
Sequence: MGQKSNPIGMRLQINRTWDSRWYADGADYGRLLLEDLKIRKHIMKAIPQAAISKVVIERPAKLCRISVYAARPGVIIGKKGADIEKLRRALGKMTSSDVSLNIVEIRKPEIDSKLVAQGVADQLERRIAFRRAMKRAVQSALRLGAEGIRITCAGRLGGAEIARTEWYREGRVPLHTLRANVDYAEAEAHTAYGVCGIKVWIFKGEILGHDPLAQDRLMMEAQTSGVRPAR
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: Y180_TREPA
Sequence: MRIESSPLPLTACLHCLPHLHPCFCPYPPPPGGNDTGTAGAFRTRALPSFTA
What are the official names of this protein?
Uncharacterized protein TP_0180.
Protein: Y1555_STAAE
Sequence: MKIKEMVTSEMPRERLLSHGAKSLSNTELLAILINTGRKGFSSIDISNELLKSASNLNELKKSSINDLIKVKGIGLQKAITLKAAFELGERMGRRAENNRIKITQPSDVADYMIPTMKDLTQEHFVILLLNSKNVVIKETCVFKGTLNSSIVHPREIFSIAVRENANAIIAVHNHPSGDVTPSQEDIITTMRLKECGLILGIDLLDHIIIGDNRFTSLVEAGYFDEND
What are the official names of this protein?
UPF0758 protein NWMN_1555.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: RL19_MYCBT
Sequence: MNRLDFVDKPSLRDDIPAFNPGDTINVHVKVIEGAKERLQVFKGVVIRRQGGGIRETFTVRKESYGVGVERTFPVHSPNIDHIEVVTRGDVRRAKLYYLRELRGKKAKIKEKR
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: DAPD_NEIM0
Sequence: MSLQNIIETAFENRADITPTTVTPEVKEAVLETIRQLDSGKLRVAERLGVGEWKVNEWAKKAVLLSFRIQDNEVLNDGVNKYFDKVPTKFADWSEDEFKNAGFRAVPGAVARRGSFVAKNVVLMPSYVNIGAYVDEGAMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQAAPTIIEDNCFIGARSEIVEGVIVEEGSVISMGVFIGQSTKIFDRTTGEIYQGRVPTGSVVVSGSMPSKDGSHSLYCAVIVKRVDAQTRAKTSVNELLRGI
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KUP4_BRASB
Sequence: MLRATALHEWLMTPTVAQDVSTRTREPQHWAALGALGIVYGDLGTSPLYTLQTVVQATGGHFTTASALGILSLLVWTLIITISIKYCLFVMRADNHGEGGILALMSLVGANRFKGTAKILAVMGLLGAALLYGDGVITPAISVLSALEGVNVVTGSLKPFVMPAAVAILIVFFAAQRFGTARIGAAFGPIMLLWFLVIAVLGLTGIVRNPSVLTALDPRHAIGFLAHSGGNGMLVLGGVFLCITGGEALYADMGHFGPGPIRLSWYAIVLPSLLLSYAGQTALLIQKGTIEGNPFFQLCPTWGVYPLVFLAMIATIIASQSIITGSFSMTRQAMQLGWLPGFHIRQTSDKVYGQIYVPVVNWMMMVATIGITIAFGSSDRLAGAYGTAVSTTMLLTTCLLFTAMRKTWRWPLAVSILIAGLFLIVDVGFFGANLLKIAEGGWLPLTFGALVFFLMLTWRSGIDAVRESLAQASEAPERFVADLAAGKVPRVPGTAIFLTRTYQKIPPLLIDHVKHMGALHQSVIALTILFEESPRIDDEERCGVEKIADGIWRVTMRFGFVEIPDLTAALKRVKGLDPSIDLDHAIYFATRDIIVARAGSSLFAHWRLPVFAFLYRNAVKVVDRFSLPPDRVVEIARQIEL
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup 4.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NU4LC_AGRST
Sequence: MMFEHVLFLSVYLFSIGIYGLITSRNMVRALICLELILNSINLNLVTFSDLFDSRQLKGDIFAIFVIALAAAEAAIGLSILSSIHRNRKSTRINQSNLLNN
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic, NAD(P)H dehydrogenase subunit 4L, NADH-plastoquinone oxidoreductase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PTLCB_STAAW
Sequence: MMQKLIAQIEKGKPFFEKLSRNIYLRAIRDGFISAMPVILFSSIFLLIAYVPNIFGFKWDKGMEAILMKPYNYTMGLVAFLVAGTTAKSLTDSFNRKLESTNQINFISTMLAAMCGFLFLASDPAKDGGFLSAFMGTKGLLTAFLSAFVTVIVYNFCVKRNITIKMPKEVPPNISQVFKDLIPFSAVIIILYALDLVIRNSFKSNVAEGILKLFEPLFTAADGWIGVTIIFGAFALFWFVGIHGPSIVEPAIAAITYANIEANFKLLQAGEHADKIITSGTQMFIVTFGGTGATLVVPFMFMWMTKSKRNKAIGRASVVPTFFGVNEPILFGAPLVLNPVFFIPFVLAPIVNVWIFKLFVEVLGMNSFSVNLPWTTPGPLGIIMGTGFGLWSFVLAITLIVVDIIIYYPFLKVYDSEILDEEEGRKESNSDLKEKVAANFDTKKADSILAASGVSDDAAKASNITEQTNVLVLCAGGGTSGLLANALNKAAEEYHVPVKAAAGGYGAHMDIMKEYQLIILAPQVASNYEDIKQDTDRLGIKLAKTQGAEYIKLTRDGQAALDFVQQQFEN
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II LacEF PTS system is involved in lactose transport.
What are the official names of this protein?
PTS system lactose-specific EIICB component, EIICB-Lac, EII-Lac.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CRTI_SYNY3
Sequence: MRVVIAGAGLAGLACAKYLADAGFTPVVLERRDVLGGKIAAWKDEDGDWYETGLHIFFGAYPNMLQLFKELDIEDRLQWKEHSMIFNQPEKPGTYSRFDFPDIPAPINGLVAILRNNDMLTWPEKIRFGLGLLPAIVQGQSYVEEMDKYTWSEWMAKQNIPPRIEKEVFIAMSKALNFIDPDEISATILLTALNRFLQEKNGSKMAFLDGAPPERLCQPLVDYITERGGEVHINKPLKEILLNEDGSVKGYLIRGLDGAPDEVITADLYVSAMPVDPLKTMVPAPWREYPEFKQIQGLEGVPVINLHLWFDRKLTDIDHLLFSRSPLLSVYADMSNTCREYSDPDKSMLELVLAPAQDWIGKSDEEIVAATMAEIKQLFPQHFNGDNPARLLKSHVVKTPRSVYKATPGRQACRPDQRTSVPNFYLAGDFTMQKYLGSMEGAVLSGKQCAQAIAADFNPQTVPPTREIVTVG
What is the function of this protein?
This enzyme converts phytoene into zeta-carotene via the intermediary of phytofluene by the symmetrical introduction of two double bonds at the C-11 and C-11' positions of phytoene.
What are the official names of this protein?
Phytoene dehydrogenase, Phytoene desaturase.
What is the protein family that this protein belongs to?
Belongs to the carotenoid/retinoid oxidoreductase family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RIBU_STRT2
Sequence: MRSLFFGIGKSIGNFFQIVKIWRNFFMTNTRKLAYIAILSAVSFLLLYFSFPLIPAADFLKVDFSILPVLIALVIFDFKSAIGVLLLRSLLKLLLNNGGPGSMIGLPMNFVALGVFVWGLSYFWKKNQTSKNYILGSVLGTILLTVAMVVLNYIYAVPLYAKFANFDIAQFIGLYKYLFAMVVPFNLLEGLIFSVAFALIYAPLKSILVKL
What is the function of this protein?
Substrate-binding (S) component of an energy-coupling factor (ECF) ABC-transporter complex.  Mediates riboflavin uptake, may also transport FMN and roseoflavin.  Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.  The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins (Probable).  Expression of the complex plus RibU in E. coli allows riboflavin uptake.
What are the official names of this protein?
Riboflavin transporter RibU, Riboflavin ECF transporter S component RibU.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL17_DESVM
Sequence: MRHSNSGKKLGRTPSHRKALFRNMAKALLTYGKIRTTETKAKELRRIVEPLITLALRNDLHSRRLAYDVLGSHQLVKRLFDDIGPAFVGVSGGFTRVVKLGLPRKGDNAPLAVIELTHQPAAEAPAEEKKAAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: PHK_LATSS
Sequence: MTDYSSKEYLAKVDAFWRAANYISVGQLYLKDNPLLQRPLEAKDVKVKPIGHWGTISGQNFLYAHLNRAINKYDLNMFYVEGPGHGGQVMVSNSYLDGSYTEIYPEISQDVDGMKKLFKQFSFPGGVASHAAPETPGSIHEGGELGYSLSHGVGAILDNPDVIAAVVVGDGEAETGPLAASWLSSTFINPKNDGAVLPILNLNGFKISNPTILSRKSDEELTKYFEGNGWAPIFVEGDDPEKMHPATAAAMDEAIEKIQAIQKAARENGDTSRPVWPMIVFRAPKGWTGPKTWDGVPIENSFRAHQIPVPIDSTDMQHADALVDWMKSYRPEELFTAEGQLKPEIAAMAPKGDKRMAANPITNGGIDPKPLRLPDYRDYAVDNTEHGKVVAQDMIVLGEYVRDIIKDNDQNKNFRIFGPDETMSNRLNHIFDVTNRQWMEPIKEPNDQFMATEGRVLDSQLSEHQAEGWLEGYVLTGRHGFFASYESFLRVVDSMLTQHFKWLRKADEQAWRNKYPSLNVIATSTVFQQDHNGYTHQDPGVLTHLAEKKPEFIREYLPADANTLLATMNTVFQSQEKINLVIASKHPRQQWFSIDEATVLVKNGLKIIDWASTDQDAEPDVVIAAAGTEPTLESLAAISILHKQYPDMKIRFINVVDLLKLRSPKVDPRGLTDEEFDMYFTKDKPVVFAFHGFEGLVRDIFFDRHNHNLHVHGYRENGDITTPFDMRVLNQMDRYNLSKEVAIDVLGDQAGQFAQSMDDMVAKHNQYIRDEGTDLPEVEEWQWTPLR
What are the official names of this protein?
Probable phosphoketolase.
What is the protein family that this protein belongs to?
Belongs to the XFP family.
Protein: DDAH2_HUMAN
Sequence: MGTPGEGLGRCSHALIRGVPESLASGEGAGAGLPALDLAKAQREHGVLGGKLRQRLGLQLLELPPEESLPLGPLLGDTAVIQGDTALITRPWSPARRPEVDGVRKALQDLGLRIVEIGDENATLDGTDVLFTGREFFVGLSKWTNHRGAEIVADTFRDFAVSTVPVSGPSHLRGLCGMGGPRTVVAGSSDAAQKAVRAMAVLTDHPYASLTLPDDAAADCLFLRPGLPGVPPFLLHRGGGDLPNSQEALQKLSDVTLVPVSCSELEKAGAGLSSLCLVLSTRPHS
What is the function of this protein?
Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS.  Has therefore a role in the regulation of nitric oxide generation.
What are the official names of this protein?
N(G),N(G)-dimethylarginine dimethylaminohydrolase 2, DDAH-2, Dimethylarginine dimethylaminohydrolase 2, DDAHII, Dimethylargininase-2, Protein G6a, S-phase protein.
What is the protein family that this protein belongs to?
Belongs to the DDAH family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Note=Translocates from cytosol to mitochondrion upon IL-1beta stimulation in chondrocytes.
Protein: IR3IP_HUMAN
Sequence: MAFTLYSLLQAALLCVNAIAVLHEERFLKNIGWGTDQGIGGFGEEPGIKSQLMNLIRSVRTVMRVPLIIVNSIAIVLLLLFG
What is the function of this protein?
Regulator of endoplasmic reticulum secretion that acts as a key determinant of brain size (PubMed:33122427).  Required for secretion of extracellular matrix proteins (PubMed:33122427).  Required for correct brain development by depositing sufficient extracellular matrix proteins for tissue integrity and the proliferation of neural progenitors (PubMed:33122427).  Acts as a regulator of the unfolded protein response (UPR) (By similarity).
What are the official names of this protein?
Immediate early response 3-interacting protein 1.
What is the protein family that this protein belongs to?
Belongs to the YOS1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: LRC41_PONAB
Sequence: MAAPEAWRARSCWFCEVAAATTMEATSREAAPAKSSASGPNAPPALFELCGRAVSAHMGVLESGVWALPGPILQSILPLLNIYYLERIEETALKKGLSTQAIWRRLWDELMKTRPSSLESVTCWRAKFMEAFFSHVLRGTIDVSSDRRLCDQRFSPLLHSSRHVRQLTICNMLQGATELVAEPNRRVLETLASSLHTLKFRHLLFSDVAAQQSLRQLLHQLIHHGAVSQVSLYSWPVPESALFILILTMSAGFWQPGPGGPPCRLCGEASRGRAPSRDEGSLLLGSRRPRRDAAERCAAALMASRRKSEAKQMPRAAPAARVTRRSTQESLTAGGTDLKRELHPPATSHEAPGTKRSPSAPAATSSASSSTSSYKRAPASSAPQPKPLKRFKRAAGKKGARTRQGPGAESEDLYDFVFIVAGEKEDGEEMEIGEVACGALDGSDPSCLGLPALEASQRFRSISTLELFTVPLSTEAALTLCRLLSSWVSLESLTLSFNGLGSNIFRLLDSLRALSGQAGCRLRALHLSDLFSPLPILELTRAIVRALPLLRVLSIRVDHPSQRDNPGVPGNAGPPSHIIGDEEIPENCLEQLEMGFPRGAQPAPLLCSVLKASGSLQQLSLDSATFASPQDFGLVLQTLKEYNLALKRLSFHDMNLADCQSEVLFLLQNLTLQEITFSFCRLFEKRPAQFLPEMVAAMKGNSTLKGLRLPGNRLGNAGLLALADVFSEDSSSSLCQLDISSNCIKPDGLLEFAKRLERWGRGAFGHLRLFQNWLDQDAVTAREAIRRLRATCHVVSDSWDSSQAFADYVSTM
What is the function of this protein?
Probable substrate recognition component of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
Leucine-rich repeat-containing protein 41.
Protein: SYT_VIBVY
Sequence: MPIITLPDGSQRQFDNSVSTMDVALSIGPGLAKATIAGRVNGQRVDACDLIEEDASLEIITTKDEVDGLEIVRHSCAHLLGHALKQLYPNAKMAIGPTIDNGFYYDIDLEESLTQEDLEKIEARMKALAKTKYQVIKKKVSWQEARDAFEARGETYKMEILDENVSRDDRPGLYHHEEYIDMCRGPHVPNMSFCQHFTLLNVAGAYWRGNSDNKMLQRIYGTAFHDKKALKDHLTRLEEAAKRDHRKIGKQLDLFHMQQEAPGMVFWHHNGWSVFRDLEVFIREKLTEYGYQEVKGPLMMDRVLWERSGHWDKYADAMFTTSSENREYAIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGALHGIMRVRGFTQDDAHIFCTESQIQDEVTNCIKMVYDTYQTFGFDNIAVKLSTRPEQRVGSDEIWDQSEEALKQALESMDIAYEIQEGEGAFYGPKIEFTLFDCLGRAWQCGTVQLDFNLPNRLGATYVGENNERLVPVMIHRAILGSLERFIGILIEEYAGFFPTWLAPEQAVIMNITDKQADYVQEIAQKLQKCGIRAKADLRNEKIGFKIREHTLKRVPFMLVCGDQEMEAGEIAVRTRKGNDLGKFKVDDFVSYIQDQIASRKLNLEE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBFA_XANOR
Sequence: MATKSFHRTDRVSAQVRRDLGTIVHAAVRDHGLPSVSVSDVEISRDLAHAKVFVTALQQERSAEAVKGLKDIAGQLRTQLARAMKLRHVPELHFHYDDSVDRGERIDNLLRDLDDVGPGATSSDEDAEQR
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIPIN_CAEBR
Sequence: MDEMDDFFGNDELDREPSPFGEEAIEDNTGEEGSRRIIEPKLLRTKKLTNPRLALNEKTLTGPKGITALREAFQNFNPNPKDDPYKNLEKMMKKYAYWGHLMFPKMKTEDVLNRVETLGTRRQVKLYIMKQRLGESTDDVENEKRETKSKNGIIDDGADDDEDDLFNDLPEKETPTKPINHTEKVVDSPEKKNGQVSNNDAEEEEYRMMEEERLREEQEAREAEAEDELMEDFDLNNDW
What is the function of this protein?
Required for normal progression of S-phase.  Important for cell survival after DNA damage or replication stress.
What are the official names of this protein?
Protein TIPIN homolog, CSM3 homolog.
What is the protein family that this protein belongs to?
Belongs to the CSM3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NDKB_MERAP
Sequence: MEQTFVAIKPDGVQRGLCGEVMKFIQPMKHYLDLKDMPFYAGLCKYMSSGPVFAMVWEGEGIVKMMLGETNPADSKPGSIRGDFCINIGRNIIHGSDTVENAKMEVGLWFKPEEFVAYAEKAKAWVYE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.
What are the official names of this protein?
Nucleoside diphosphate kinase B, NDK B, NDP kinase B.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell projection, lamellipodium. Cell projection, ruffle.
Protein: YAIT_ECOLI
Sequence: MHSWKKKLVVSQLALACTLAITSQANAANYDTWTYIDNPVTALDWDHMDKAGTVDGNYVNYSGFVYYNNTNGDFDQSFNGDTVNGTISTYYLNHDYADSTANQLDISNSVIHGSITSMLPGGYYDRFDADGNNLGGYDFYTDAVVDTHWRDGDVFTLNIANTTIDDDYEALYFTDSYKDGDVTKHTNETFDTSEGVAVNLDVESNINISNNSRVAGIALSQGNTYNETYTTESHTWDNNISVKDSTVTSGSNYILDSNTYGKTGHFGNSDEPSDYAGPGDVAMSFTASGSDYAMKNNVFLSNSTLMGDVAFTSTWNSNFDPNGHDSNGDGVKDTNGGWTDDSLNVDELNLTLDNGSKWVGQAIYNVAETSAMYDVATNSLTPDATYENNDWKRVVDDKVFQSGVFNVALNNGSEWDTTGRSIVDTLTVNNGSQVNVSESKLTSDTIDLTNGSSLNIGEDGYVDTDHLTINSYSTVALTESTGWGADYNLYANTITVTNGGVLDVNVDQFDTEAFRTDKLELTSGNIADHNGNVVSGVFDIHSSDYVLNADLVNDRTWDTSKSNYGYGIVAMNSDGHLTINGNGDVDNGTELDNSSVDNVVAATGNYKVRIDNATGAGAIADYKDKEIIYVNDVNSNATFSAANKADLGAYTYQAEQRGNTVVLQQMELTDYANMALSIPSANTNIWNLEQDTVGTRLTNSRHGLADNGGAWVSYFGGNFNGDNGTINYDQDVNGIMVGVDTKIDGNNAKWIVGAAAGFAKGDMNDRSGQVDQDSQTAYIYSSAHFANNVFVDGSLSYSHFNNDLSATMSNGTYVDGSTNSDAWGFGLKAGYDFKLGDAGYVTPYGSVSGLFQSGDDYQLSNDMKVDGQSYDSMRYELGVDAGYTFTYSEDQALTPYFKLAYVYDDSNNDNDVNGDSIDNGTEGSAVRVGLGTQFSFTKNFSAYTDANYLGGGDVDQDWSANVGVKYTW
What are the official names of this protein?
Putative uncharacterized protein YaiT.
Protein: AROG_MYCTU
Sequence: MNWTVDIPIDQLPSLPPLPTDLRTRLDAALAKPAAQQPTWPADQALAMRTVLESVPPVTVPSEIVRLQEQLAQVAKGEAFLLQGGDCAETFMDNTEPHIRGNVRALLQMAVVLTYGASMPVVKVARIAGQYAKPRSADIDALGLRSYRGDMINGFAPDAAAREHDPSRLVRAYANASAAMNLVRALTSSGLASLHLVHDWNREFVRTSPAGARYEALATEIDRGLRFMSACGVADRNLQTAEIYASHEALVLDYERAMLRLSDGDDGEPQLFDLSAHTVWIGERTRQIDGAHIAFAQVIANPVGVKLGPNMTPELAVEYVERLDPHNKPGRLTLVSRMGNHKVRDLLPPIVEKVQATGHQVIWQCDPMHGNTHESSTGFKTRHFDRIVDEVQGFFEVHRALGTHPGGIHVEITGENVTECLGGAQDISETDLAGRYETACDPRLNTQQSLELAFLVAEMLRD
What is the function of this protein?
Catalyzes an aldol-like condensation reaction between phosphoenolpyruvate (PEP) and D-erythrose 4-phosphate (E4P) to generate 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAH7P) and inorganic phosphate.
What are the official names of this protein?
Phospho-2-dehydro-3-deoxyheptonate aldolase AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase, DAHP synthase, Phospho-2-keto-3-deoxyheptonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class-II DAHP synthase family.