PharMolix/UniProtQA huggingface dataset:
Protein: MTBF_BACIU
Sequence: MRGGNRLGAGRKVIPESEKKKRKSVYITDKLYTRIMDTDIENCNNFSQKCMALIELAMENLNKNNQEHSVKRNNILMVRDTKSTYNKTNNNFEKQNRGIKLTFIDLFAGIGGIRLGFEDKYTKCVFSSEWDKYAAQTYEANYGEKPHGDITKINENDIPDQDVLLAGFPCQPFSNIGKREGFAHERRNIIFDVLRILKKKQPKMFLLENVKGLLTNDNGNTFRVILDNLKSLGYSVFYEVMDAQNFGLPQRRERIVIVGFHPDLGINDFSFPKGNPDNKVPINAILEHNPTGYSISKRLQESYLFKKDDGKPQIVDFRCTYQVNTLVASYHKIQRLTGTFVKDGETGLRLFSELELKRLMGFPVDFKVPVSRTQMYRQFGNSVAVPMIKAVAGAMKERLLLAEMQVLKK
What is the function of this protein?
A methylase, recognizes the double-stranded sequence 5'-CCGG-3', methylates C-1 on both strands, and protects the DNA from cleavage by the BsuFI endonuclease.
What are the official names of this protein?
Type II methyltransferase M.BsuFI, M.BsuFI, Cytosine-specific methyltransferase BsuFI, Modification methylase BsuFI.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
Protein: NUSA_RICPR
Sequence: MSNIYNIEILQIIDSVAREKGISKEILISTVEQAVQVAGRKKYGNEYNIKAQINRKTGEINLLRILKIVEDVEDYLTQISLEDALVKNPEAKIGDEIYEYLPPIDHARVSAQAAKQVITQRVIEAEREKQYHDFKDRKGDIINGIVKRIEYGDIIVDLSRAEAIIKKDQLIKGEHFKPNDRIKAYVQDVRQETKGPQIFLSRVDNQMLVKLFKLEVPEILEDIIQIKSVARDPGSKAKIAVFASDSSIDPVGSCVGIRGNRVKAVTNELNGEKIDIVLWSNDLAQFIVNSLIPLAPSEITKILIDEDSHKVEVVVSQEHQSIAIGRRGQNVRLASKLTGWNIDIMTEEQESKRRNEEFSTSTELFMEALDVEEVIGQLLSVTGFNSVEQIASSEISTLTRIEGFEEELAVEIKNRAIHYVDLKNEKIIKKLEELGVEQELIDILELPLELILKFAEYGIKTIEDLGEMSVNEFKNLAPNSNITDENIKLLIKTARHHGELKDS
What is the function of this protein?
Participates in both transcription termination and antitermination.
What are the official names of this protein?
Transcription termination/antitermination protein NusA.
What is the protein family that this protein belongs to?
Belongs to the NusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYA_BORAP
Sequence: MTLDKLRKKYIDFFKSKKHFEIMGKSLVPENDPTVLFNTAGMQPLIPYLLGEVHPSGDMLVNVQKCLRTGDIDEVGDLSHLTFFEMLGNWSLGAYFKEYSVKCSFEFLTSSEYLNIPKDRLYVSVFEGDQEIPRDTETAKVWESLGIPKDRIYYLSKDHNFWGPVGSKGPCGPDTEIYVDTGKIKCSINCNVTCSCGKYFEIWNNVFMQYNKDENGNYMELDRKCVDTGMGLERTIAFLQGKSSVYDTDAFMPIIKRIEFISGKIYGQKEDDDRCIRIISDHIKAACFILADSSGVFPSNLGQGYVLRRLIRRSIRYAKKLGIKSHFLADLVDSVETIYRSFYNELTEKKDFIKKELSTEEEKFFKTLFQGEQEFIKITRNLSSKTIPGDIAFKLYDTYGFPYELTEELAFEYGFDIDKSGFNEYFKKHQKTSKKGGDKVFKGGLADYTYETTKLHTATHLLHKALQLVLGDHVKQKGSNITAERLRFDFVHSKKMTDDEIKKVEDIVNLQIKNSLSVKKSIMELSEAREKGAMALFGEKYDNLVSVYEIDGFSLEVCGGPHVENTNELGTFKIQKEQSSSSGIRRIKAILIDE
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity).
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERBB_AVIEU
Sequence: MKCAHFIDGPHCVKACPAGVLGENDTLVWKYADANAVCQLCHPNCTRGCKGPGLEGCPNGSKTPSIAAGVVGGLLCLVVVGLGIGLYLRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQAHLRILKETEFKKVKVLGFGAFGTVYKGLWIPEGEKVTIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPYGCLLDYIREHKDNIGSQYLLNWCVQIAKGMNYLEERHMVHRDLAARNVLVKTPQHVKITDFGLAKQLGADEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSVLEKGERLPQPPICTIDVYMIMVKCWMSDADSRPKFRELIAEFSKMARDPPRYLVIQGDERMHLPSPTDSKFYRTLMEEEDMEDIVDADEYLVPHQGFFNSPSTSRTPLLSSLSATSNNSATNCIDRNGGHPVREDGFLPAPEYVNQLMPKKPSTAMVQNQIYNYISLTAISKLPIDSRYQNSHSTAVDNPEYLE
What are the official names of this protein?
Tyrosine-protein kinase transforming protein erbB.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
Protein: D10_RFVKA
Sequence: MNERLQYSHLMNYITKHNRKLSKTYTWNDDSQRVSATGFSNQRLRWSNKTSICLILSTLDNKFIACSRKHSFLYSEIVRCRSVFRKKRLFLTYTRFLKKKERPFLSSKLNVPLDDPGTEHNDIIFPGGLPKNEEDPIMCLSREIKEEINIDSKDIYIDSRFFVHLFIEDLLSNRVYETILFLGNTTLTSNEILNNFLANREIKSLVFLDALEKGLMCDVLRYVLAISQLKCFGSTGDKTELLYDKVTESEKKMAPRYGFD
What is the function of this protein?
Decapping enzyme required for the removal of the 5'-end m7GpppN cap tethered to viral and host mRNAs to allow their decay in cells.  May therefore accelerate viral and cellular mRNA turnover to eliminate competing host mRNAs and allow stage-specific synthesis of viral proteins.  Acceleration of the turnover of cellular transcripts may even promote the shutoff of host protein synthesis (By similarity).
What are the official names of this protein?
mRNA-decapping protein D10.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
Protein: RL6_THEAQ
Sequence: MSRIGRLPIPVPKGVQVQVSPGLVKVKGPKGELSVPVSPELKVVVEENVVRVERPSDERRHRSLHGLTRTLIANAVKGVSEGYVKELLIKGIGYRARLVGRSIELTVGFSHPVVVEPPEGITFEVPEPTRIRVLGIDKQKVGQVAADIRAIKKPSAYHEKGIYYADEPVRLKPGKAGAKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: MSRA_YERPA
Sequence: MQNVDNTAVIDAANALPGRLTSIPVSPLHAVHGHSMTYIPEGMDLAFFAMGCFWGAERLFWQQPGVYSTAAGYSGGHTPNPTYHEVCSGRTGHAEVVRVVFDPAVISYQQLLQIFWENHDPAQGMRQGGDVGTQYRSAIYVLTPEQEEQAHKSRERFQQAMEKAGDQRVITSEITVALPFYYAEDDHQQYLHKNPHGYCGLGGIGVCLPPNV
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: RLMH_DEIRA
Sequence: MRLHLITVGEPKLAYARSGWDEYEKRLRRYHKVQVSRVSGKTQQAESEAILKAAGKSPLILLDPRGKQFSSEKLSEYLDAEALGGHGELAFAIGGPDGHTDALRGQAKLLWSLGELTLPHDLAMLVLVEALYRAATISAGEPYHRG
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_RHILO
Sequence: MALKIRLARAGSKKRPYYHVVVADARSPRDGRFIESLGSWNPLLPKDGERVKVDADRVKHWLSHGAQPTDRVLRFLDEAGLAKRDARSNPKKAEPGKKAQERAALLKKAQEDAAAAVAAAAAAPAEAEAATAE
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: LAMA4_HUMAN
Sequence: MALSSAWRSVLPLWLLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGECLEEGFEPPTGMDCPTISCDKCVWDLTDALRLAALSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSLLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYYGEEHELSPKEISEKLVLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLSQAESWQRLHNETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTVEQKRPASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSMFFRLEMRNGYLHVFYDFGFSGGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQPNGLLFYYASGSDVFSISLDNGTVIMDVKGIKVQSVDKQYNDGLSHFVISSVSPTRYELIVDKSRVGSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLPERNTPRNSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGMIFYVSDQEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSKAALVSGAVSINSCPAA
What is the function of this protein?
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
What are the official names of this protein?
Laminin subunit alpha-4, Laminin-14 subunit alpha, Laminin-8 subunit alpha, Laminin-9 subunit alpha.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix, basement membrane. Note=Major component.
Protein: RL33_SHELP
Sequence: MAKAKGNREKIKLVSSAKTGHFYTTEKNKRNMPEKMEIKKFDPVIRQHVIYKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: ISDA_STAAT
Sequence: MTKHYLNSKYQSEQRSSAMKKITMGTASIILGSLVYIGADSQQVNAATEATNATNNQSTQVSQATSQPINFQVQKDGSSEKSHMDDYMQHPGKVIKQNNKYYFQTVLNNASFWKEYKFYNANNQELATTVVNDNKKADTRTINVAVEPGYKSLTTKVHIVVPQINYNHRYTTHLEFEKAIPTLADAAKPNNVKPVQPKPAQPKTPTEQTKPVQPKVEKVKPTVTTTSKVEDNHSTKVVSTDTTKDQTKTQTAHTVKTAQTAQEQNKVQTPVKDVATAKSESNNQAVSDNKSQQTNKVTKHNETPKQASKAKELPKTGLTSVDNFISTVAFATLALLGSLSLLLFKRKESK
What is the function of this protein?
Cell wall-anchored surface receptor that participates in the extraction of heme from oxidized methemoglobin/metHb to enable growth on hemoglobin as a sole iron source (By similarity).  Receives heme from IsdB and transfers it to IsdC (By similarity).  Also plays a role in the inhibition of host immune response.  Protects S. aureus against the bactericidal protease activity of apolactoferrin.  Decreases bacterial cellular hydrophobicity, which renders S. aureus resistant to bactericidal human skin fatty acids as well as to beta-defensins and cathelicidin.  Also binds fibronectin and chains B-beta and gamma of fibrinogen, promoting clumping of S. aureus with fibrinogen.  Involved in adherence of S. aureus to human desquamated nasal epithelial cells and is required for nasal colonization (By similarity).
What are the official names of this protein?
Iron-regulated surface determinant protein A, Fur-regulated protein A, Staphylococcal transferrin-binding protein A.
What is the protein family that this protein belongs to?
Belongs to the IsdA family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor. Note=Encodes an LPXTG motif-containing sorting signal that targets to the cell wall, which is catalyzed by sortase A.
Protein: MURB_NOSP7
Sequence: MTISQAAGNVCTVSALNTKKHQTTNSVDSEVIYLPNTDCTIKSQACLSAFTSYRVGGAADLYVAPRNLEALQASLKYAKEGDLKVTTLGAGSNLLVSDGGISGLVIATRHLRFSHFDPQTGQLTVAAGESIPSLAWAAAELGWQGLEWAVGIPGTAGGAVVMNAGAHNSCIADMLVSAEVLSPDGTLETLTPEQLGYSYRTSLLQGGDRIVTQATLQLAPGADPAKVVAITKEHKKHRLSTQPYNFPSCGSVFRNPKPYSAGWLIEQTGLKGYQIGGAQVALLHANFIVNRGGAKASDIFCLIRHIQHQVQERWSINLEPEVKMLGEFQGAC
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_RUEST
Sequence: MRSGIIAKKVGMTRLFMEDGKQIPVTVLSLDGLQVVAQRTEDKDGYTAVQLGAGSAKVKRVSKAMRGHFAASKVEPKRKLVEFRVPADGLIEVGAEISAEHFLEGQKVDVTGTSIGKGFAGAMKRWNFGGLRASHGVSISHRSHGSTGQCQDPGKVFKGKKMAGHMGAARVTTQNLEVVKTDADRGLVFIKGAVPGPKSGWVTVKDAVKKKAPEGLPFPAALKTAAEAAAEAPAEGGEA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: BETI_YERPP
Sequence: MPKVGMQPIRRQQLIEATMAAVNEVGMHEASIAQIAKRAGVSNGIISHYFRDKNGLLEATMRYLIRHLGEAVKQHLAALSVNDPRARLRAIAEGNFDDSQINSAAMKTWLAFWASSMHSPQLYRLQQVNNRRLYSNLCAEFKRCLPREQAQLAAKGMAGLIDGLWLRSALSGEHFNRQEALLIIHNYIEQQLNIKYKC
What is the function of this protein?
Repressor involved in the biosynthesis of the osmoprotectant glycine betaine.  It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator BetI.
Protein: HMS1_YEAST
Sequence: MPNFQKPFSGSSDGNSVMNDLGNKVAIKVFDCRSAQDGSEEQNVNVTTNQMYLMFQSNNYNVPPPNYNTEDLGSQGPPTHAYYAPFQHPIHLQPPVPPVYKNNTYSATDQYSDSSFPNTSGHTPVIDSNYYNDALASIPTTTTGSTTMTTDNGNTIDSEEYIDNMEVFSSEENENIDNVKQTDLKSEKDSSLLSAASIVKKEQLSGFENFLPLSKTESPLVTADEIKSSLNLENIDNADSMSFKLKTSPIRKHFHVKPKRITRVRTGRVSHNIIEKKYRSNINDKIEQLRRTVPTLRVAYKKCNDLPITSRDLADLDGLEPATKLNKASILTKSIEYICHLERKCLQLSLANQHLSNDTRDSFVHLTEPSQPLSDNSSSEQVQKQTRSCQRQRQRQPRQQQPLHNIQYNIPHQNGLMSGTNNSHDMDFNNAGDF
What is the function of this protein?
Involved in exit from mitosis and pseudohyphal differentiation.
What are the official names of this protein?
Probable transcription factor HMS1, High-copy MEP suppressor protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: GSTP1_HUMAN
Sequence: MPPYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTVETWQEGSLKASCLYGQLPKFQDGDLTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYTNYEAGKDDYVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDAFPLLSAYVGRLSARPKLKAFLASPEYVNLPINGNGKQ
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.  Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2) (PubMed:9084911).  Participates in the formation of novel hepoxilin regioisomers (PubMed:21046276).  Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration.
What are the official names of this protein?
Glutathione S-transferase P, GST class-pi, GSTP1-1.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Pi family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Nucleus. Note=The 83 N-terminal amino acids function as un uncleaved transit peptide, and arginine residues within it are crucial for mitochondrial localization.
Protein: PURL_BRASO
Sequence: MRNEPQITPELVAAHGLKPDEYERILKLIGREPTFTELGIFSAMWNEHCSYKSSRIHLKGLPTKAPWVIQGPGENAGVIDIGDGQAVVFKMESHNHPSYIEPYQGATTGVGGILRDVFTMGARPIACLNALSFGAPEHPKTRHLVSGVVAGIGGYGNSFGVPTVGGQTRFHTRYDGNILVNAMAVGLADADKIFYAAASGVNMPIVYLGSKTGRDGIHGASMASAEFDDSSEEKRPTVQVGDPFAEKLLLEACLEIMAADCVIAIQDMGAAGLTCSAVEMGAKGDLGVDLDLDSVPTRETGMSAYEMMLSESQERMLMVLKPEKEKEAEAIFRKWGLDFAVVGYTTPSKRFVVKHGGDVMADLPIKELGDEAPLYDRPHVASPALPVIHAREVKAPMAIIPALEKLIATPDLCSKRWIWEQYDHVILGNTVQRPGGDAAVVRVQDGPKGLALTVDVTPRYCEADPFEGGKQAVAEAWRNITAVGGRPLAITDNLNFGNPERPEIMGQFVGCLKGISEACRALDFPVVSGNVSLYNETNGRAILPTPSIGGVGLLDDFTKSASIAFKTEGEAILLIGETHGWLGQSVYLRDVCGREEGAPPPVDLAAEKRIGDVVRGMIHAGTATAAHDLSDGGLLVALAEMAMASGIGARLLAAPASIVPHAYWFGEDQARYLVTVPETEAGRVLAKMRGANVPCTRIGTTGGTALAIAGEASVEVATLRTRFESWLPGYMGGAAA
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_BACMK
Sequence: MNKEERAKRQSKIRNFSIIAHIDHGKSTLADRILEKTNALAQREMKAQLLDSMELERERGITIKLNAVQLTYKAKDGEEYILHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNNLEILPVINKIDLPSADPERVRQEVEDVIGLDASEAVLASAKAGIGIEDILEQIVEKVPAPTGDSEEPLQCMIFDSLYDPYRGVIAYIRVVNGTVKVGDKVRMMATGKEFEVTEVGVFTPKTTQRDELTVGDVGFLAASIKNVGDTRVGDTITHAKRPAAEPLKGYRKLNPMVFCGLYPIDSARYNDLRDALEKLELNDSALEFEPETSQALGFGFRCGFLGLLHMEIIQERIEREFKIDLITTAPSVIYKVYLTNGEDFIVDNPSNMPDPQTIDRVEEPFVKAAIMVPNDYVGAVMEICQGKRGTFIDMQYLDETRVTLTYEIPLSEIVYDFFDQLKSNTKGYASFDYELIGYKPSKLVKMDILLNNEQVDALSFIVHRDSAYDRGKVIVEKLKKLIPRQQFEVPIQATIGNKVVSRSTIKAMRKNVLAKCYGGDISRKRKLLDKQKEGKKRMKSVGSVEVPQEAFMAVLKMDDN
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: FUCM_SHIFL
Sequence: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMEPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
What is the function of this protein?
Involved in the anomeric conversion of L-fucose.
What are the official names of this protein?
L-fucose mutarotase, Fucose 1-epimerase, Type-2 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. FucU mutarotase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_HAEIN
Sequence: MTQKLHIKTWGCQMNEYDSSKMADLLLSTHGLELTEAPEEADVLLLNTCSIREKAQEKVFHQLGRWKELKKNNPNLVIGVGGCVASQEGEHIRHRAPYVDIIFGPQTLHRLPEMINQIRGGKSSVVDVSFPEIEKFDRLPEPRAEGPTAFVSIMEGCNKYCTFCVVPYTRGEEVSRPVDDVLFEIAQLAEQGVREVNLLGQNVNAYRGPTHDGQICSFAELLRLVASIDGIDRLRFTTSHPIEFTDDIIDVYRDTPELVSFLHLPVQAGSDRVLTMMKRAHTALEYKSIIRKLRAVRPDIQISSDFIVGFPGETAEDFEQTMNLIAQVNFDMSFSFVYSARPGTPAADMPDDVTEDEKKQRLYVLQERINQQAAQFSRRMLGTEQRVLVEGPSKKDIMELTGRTETNRIVNFQGSPEMIGKFVDVKITDVYTNSLRGEVVRTEDEMGLRIAQSPQEVMNRTRKEDELGVGRYHG
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XERD_LEPIC
Sequence: MTSSHNNLLQNFQEYLSVEKGLSDNSIYSYGYDLNKFKNFLEKEHIDFLKVQADDIMRFLNEEKDRKISSKTIAREVVAIRQFYKFLKDEKKLDTNPTEKIETPEVMRSIPDYLTQDEIEELFASIKEDNLYELRDKCIFELLYSSGLRISEACNLRLNDMDLEGMTLTVEGKGGRQRLVPFGEKSLDILNRYLKQSRPFILKSRNCEYLFVSKKGSYINRKSVWRLLNHYIKRTSILKKVTPHTLRHSFATHLLENHADLKSVQELLGHIDIATTQIYTHMANKTLREVHKKFHPRG
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerD.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DFB33_MOUSE
Sequence: MRLLFLLFILLVCLAQTTSGRKRNSKFRPCEKMGGICKSQKTHGCSILPAECKSRYKHCCRL
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Beta-defensin 33, BD-33, mBD-33, Defensin, beta 33.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL17_FUSNN
Sequence: MNHNKSYRKLGRRADHRKAMLKNMTISLIKAERIETTVTRAKELRKFAERMITFGKKNTLASRRNAFAFLRDEEVVAKIFNEIAPKYAERNGGYTRIIKTSVRKGDSAEMAIIELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: GPDA_NITHX
Sequence: MKTLNRVSVIGAGAWGTALAGVAARAGREVTLYARDAATAAAISATRDNPRLPGIPLDRSIVVTHDLAAAGRADIIVIAVPAQNSRTAVAALAPHLAAGTPVIASAKGIEHGTRRFMTEVIEEAAPQTVPAILSGPSFADDVARGLPTAVTLAAKDEAMAVALVHALGSAAFRPYHTTDLRGVEIGGAAKNVLAIAAGIVVGKQLGASAQAALTTRGFSELVRLGLACGARSETLSGLSGLGDLILTCSSPQSRNFSLGIALGRGESAPRGKLSEGAFTAPALLELAAANGVEMPVANAVAAILAGRLTIDAAIDNLLTRPFRAEG
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REQ2_ECOLI
Sequence: MNLEALPKYYSPKSPKLSDDAPATGTGCLTITDVMAAQGMVQSKAPLGLALFLAKVGVQDPQFAIEGLLNYAMALDNPTLNKLSEEIRLQIIPYLVSFAFADYSRSAASKARCEHCSGTGFYNVLREVVKHYRRGESVIKEEWVKELCQHCHGKGEASTACRGCKGKGIVLDEKRTRFHGVPVYKICGRCNGNRFSRLPTTLARRHVQKLVPDLTDYQWYKGYADVIGKLVTKCWQEEAYAEAQLRKVTR
What is the function of this protein?
Positively regulate expression of some phage genes.  Bacterial host RNA polymerase modified by antitermination proteins transcribes through termination sites that otherwise prevent expression of the regulated genes (By similarity).
What are the official names of this protein?
Prophage antitermination protein Q homolog QuuQ, Antitermination protein Q homolog from lambdoid prophage Qin.
What is the protein family that this protein belongs to?
Belongs to the phage antitermination Q type 2 family.
Protein: RS7_MYCPN
Sequence: MRKNRAPKRTVLPDPVFNNTLVTRIINVIMEDGKKGLAQRILYGAFDLIEQRTKEKPLTVFERAVGNVMPRLELRVRRIAGSNYQVPTEVPQDRKIALALRWIAMFARKRHEKTMLEKIANEIIDASNNTGAAIKKKDDTHKMAEANKAFAHMRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.