PharMolix/UniProtQA huggingface dataset:
Protein: FDHD_PECAS
Sequence: MQVFQVKEVHSQADAVLEGATQHSVYHPDSLHQPQSDWLAEEVPVALVYNGISHVVMMASPKELEQFALGFSLSEGIIQSPADIYGIDVQNACNGIEVQIELSSRRFAGLKERRRSMDGRTGCGVCGVEQLAEIGKPVAPLPFTQTFSLSKLENALVRLRDVQKIGQVTGCTHAASWIAPDGTLSGGSEDVGRHVALDKLLGARAKQGWQQGAALVSSRASYEMVQKSAMCGVEILFAVSAATSLAVDVAQRCNLTLVGFCRPGQATIYTHPQRLSE
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity.  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
What are the official names of this protein?
Sulfur carrier protein FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUC1A_CHICK
Sequence: MGNMDGKAVEELSATECHQWYKKFMTECPSGQLTLYEFKQFFGLKNLSPSANKYVEQMFETFDFNKDGYIDFMEYVAALSLVLKGKVDQKLRWYFKLYDVDGNGCIDRGELLNIIKAIRAINRCNEAMTAEEFTNMVFDKIDINGDGELSLEEFMEGVQKDEVLLDILTRSLDLTHIVKLIQNDGKNPHAPEEAEEAAQ
What is the function of this protein?
Stimulates retinal guanylyl cyclase when free calcium ions concentration is low and inhibits guanylyl cyclase when free calcium ions concentration is elevated.  This Ca(2+)-sensitive regulation of retinal guanylyl cyclase is a key event in recovery of the dark state of rod photoreceptors following light exposure.
What are the official names of this protein?
Guanylyl cyclase-activating protein 1, GCAP 1, Guanylate cyclase activator 1A.
Protein: MED26_MOUSE
Sequence: MTAAPASPQQMRDRLLQAIDSQSNIRNMVAVLEVISSLERYPITKEALEETRLGKLINDVRKKTKNEELAKRAKRLLRSWQKLIEPVHQNEVALRALAGAAGSANGGAHNCRPEMGVAGAPKSIHDLKNRNDIQRLPGQRLDRLGSRKRRGDQRDLGHPGPPHKVSKGSPDPLVPNASPLPTNGISGSPESLPSPLDGSGHLGPDGSRLEPSDNEKHSTKIPVNAVRPRPSSPGLGKPPVPCLQTKAAQLQQLDRADESPGPPYPRGSSRCSFSPRNSRHEGSFSRHRSSYIPKGQVSSPSPWPQPPDNTQVPSPLPLAQPPTPPVRRQELLPNAESPVHWPEQSEGHPRLTGPACRAGFSPDSSKADSDATSSGGSDSKKKKRYRPRDYTVNLDGQVAEAGVKPVRLKERKLTFDPMTRQIRPLTQKEPVRADSPVPTEQLPRTELEQQEVKASLQSPFEQTNWKELSRNEIIQSYLSRQSSLLSSSGAQTPGAHHFMAEYLKQEESSRQGARQPHVLLPLPTPTDLPGLTREVTQDDLDRIQAQQWPGVNGCEDTQGNWYDWTQCISLDPHGDDGRLNILPYVCLD
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 26, Cofactor required for Sp1 transcriptional activation subunit 7, CRSP complex subunit 7, Mediator complex subunit 26.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 26 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MRAZ_LACP7
Sequence: MFMGEYNHIIDAKGRIIVPSKFRDSLGEHFVVTVGLDGCLFVYPNEEWQHFVEQLKNLPGNKEARQLQRYFMAGAADCEVDKQGRILIPGNLRQHAGLDKDIVFVGVLSKIEIWSKERWESNSYDNMDEIADHMSEFGLSF
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: VGLN_BEFVB
Sequence: MFLQLFNIVLIYGVRTSQSTWINYPENCTSISLQDGLRELCGGDQLMNIRNQLLDDTYKEIGEICTPNYSMEKKSEGYRCASIKKKVICKMLENFDHEVTYISESHPIDKAKCHELIINKDLLNNIEEPYYPPPKCDSSKSSVSELEFIKLINYDVILDPVGFQNEDNYLFQFDKTNPIPIDYIYQSEFCQSKNWICHGDKSYIPLEIFKGDNQASIRLELIKLSIIYDSNFGELPIRDACRLHYCGKPAIKLFNGAIIKIKESPIVLGLPSCNRSRIEMPETNLAKKRYSNVGPVLLTTLNKRFELCKKIKKNLELKQPIPINNLHYLAPFEPGKHPALVYRLVSTTINQSLRNKVVPVSMLSMSMCEYITGQIIEDGIKRNLTDEDTVIILANNKEIKWKDLKGRENWYQEQANPNIIDKNPDHLSYYWYNGVMRREDKFTYPSRYILQTLKKIYTDTERESRISFFKFRLERNITKTEVIKFRDIEESSDQDHSQSVNKTLEGDDYWNWVEETTSDKNKTDGSRGDEKQTIQNKEYWNEESSIWGISTIITVLGIYYIYRKNRREKIFLNMKHRVQRFFKLDY
What are the official names of this protein?
Non-structural glycoprotein GNS.
What is the protein family that this protein belongs to?
Belongs to the ephemerovirus glycoprotein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass type I membrane protein.
Protein: ISPE_RHIL3
Sequence: MMSSENRSHFSASCSSITEEARAKINLALHVTGQRPDGYHLLDMLVTFADHGDRLDFVPSPTDAFTLSGRFGGTLAGGSGTNLVLKARDLLRAAIGPLAFPVRIHLEKNLPIASGIGGGSADAAATLRGLTRLWGATLPEEALAALALKLGADVPMCLESRPLIARGIGEELEPVPELPAFAMVLANPLKGVSTPEVFRRLAEKNNPALSLALSRPQTADWLAAIAAARNDLEPPARELVPEIAAISAMLQAHGALLTRMSGSGATCFGIFATMAAAKDAAAALHEARLDWYFQATETVSGGV
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: CRTQ_STAA3
Sequence: MKWLSRILTVIVTMSMACGALIFNRRHQLKAKTLNFNHKALTIIIPARNEEKRIGHLLHSIIQQQVPVDVIVMNDGSTDETARVARSYGATVVDVVDDTDGKWYGKSHACYQGVTHACTNRIAFVDADVTFLRKDAVETLINQYQLQGEKGLLSVQPYHITKRFYEGFSAIFNLMTVVGMNVFSTLDDGRTNQHAFGPVTLTNKEDYYATGGHKSANRHIIEGFALGSAYTSQSLPVTVYEGFPFVAFRMYQEGFQSLQEGWTKHLSTGAGGTKPKIMTAIVLWLFGSIASILGLCLSLKYRQMSVRKMVALYLSYTTQFIYLHRRVGQFSNLLMVCHPLLFMFFTKIFIQSWKQTHRYGVVEWKGRQYSISKEQ
What is the function of this protein?
Catalyzes the glycosylation of 4,4'-diaponeurosporenoate, i. e.  the esterification of glucose at the C1'' position with the carboxyl group of 4,4'-diaponeurosporenic acid, to form glycosyl-4,4'-diaponeurosporenoate.  This is a step in the biosynthesis of staphyloxanthin, an orange pigment present in most staphylococci strains (By similarity).
What are the official names of this protein?
4,4'-diaponeurosporenoate glycosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. CrtQ subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DDL_GEOSL
Sequence: MTRDELKTTKIGVLMGGLSAEREVSLASGGAVLKALQSRGYDAVPVDVGRDLPQVLVREWIDVAFICLHGRYGEDGTVQGLLELMGIPYTGSGVLASALAMNKIVAKEVFAARGLTIAPYRVVRRGETVDPVAEGFGYPVVVKPSQEGSSVGVSIVKSPEELPSALELAFRYDDDILVERFIKGREIQIGILDDRAMGAIEIVPVNEFYDFEAKYTAGKAEHICPPVLPAELHRRLLAEGEAAHRALGCSGYSRVDFLVTEGGECYLLEVNTLPGMTALSLLPEIALKESGIGFEDLVERILISAELKIKGEGAGS
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_ACIF2
Sequence: MTARRIDGKAIAQKIHADISLRSHAFLRQWGRSPGLAVVLVGADPASRIYVQKKRETCASVGIASFSANLPADTNPQQLLAHIGELNVNDAVDGILVQLPLPPHFDPEEIIEAIAVEKDVDGFHPYNIGRLALRAPLLRSCTPAGIMTLLQESGIDIKGKEAVIVGASNIVGRPMALELLLAGATVTVCHRFTRDLAAHVGRAELLVAAAGKPGLISGAWIREGAVVIDVGINRLPDGRVTGDVDFAGAEQRAAWITPVPGGVGPMTVATLLQNTLIAAEHRMGAPHV
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: IDHC_HUMAN
Sequence: MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
What is the function of this protein?
Catalyzes the NADP(+)-dependent oxidative decarboxylation of isocitrate (D-threo-isocitrate) to 2-ketoglutarate (2-oxoglutarate), which is required by other enzymes such as the phytanoyl-CoA dioxygenase (PubMed:10521434, PubMed:19935646).  Plays a critical role in the generation of NADPH, an important cofactor in many biosynthesis pathways (PubMed:10521434).  May act as a corneal epithelial crystallin and may be involved in maintaining corneal epithelial transparency (By similarity).
What are the official names of this protein?
Isocitrate dehydrogenase [NADP] cytoplasmic, IDH, IDH1, Cytosolic NADP-isocitrate dehydrogenase, IDPc, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Peroxisome.
Protein: NANK_ECOLC
Sequence: MTTLAIDIGGTKLAAALIGADGQIRDRRELPTPASQTPEALRDALSALVSPLQAHAQRVAIASTGIIRDGSLLALNPHNLGGLLHFPLVKTLEQLTNLPTIAINDAQAAAWAEYQALEGDITDMVFITVSTGVGGGVVSGGKLLTGPGGLAGHIGHTLADPHGPVCGCGRTGCVEAIASGRGIAAAAQGELAGADARTIFTRAGQGDEQAQQLIHRSARTLARLIADIKATTDCQCVVVGGSVGLAEGYLALVEMYLAQEPAAFHVDLLAAHYRHDAGLLGAALLAQGEKL
What is the function of this protein?
Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P.
What are the official names of this protein?
N-acetylmannosamine kinase, ManNAc kinase, N-acetyl-D-mannosamine kinase.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family. NanK subfamily.
Protein: TYRA_ECOLI
Sequence: MVAELTALRDQIDEVDKALLNLLAKRLELVAEVGEVKSRFGLPIYVPEREASMLASRRAEAEALGVPPDLIEDVLRRVMRESYSSENDKGFKTLCPSLRPVVIVGGGGQMGRLFEKMLTLSGYQVRILEQHDWDRAADIVADAGMVIVSVPIHVTEQVIGKLPPLPKDCILVDLASVKNGPLQAMLVAHDGPVLGLHPMFGPDSGSLAKQVVVWCDGRKPEAYQWFLEQIQVWGARLHRISAVEHDQNMAFIQALRHFATFAYGLHLAEENVQLEQLLALSSPIYRLELAMVGRLFAQDPQLYADIIMSSERNLALIKRYYKRFGEAIELLEQGDKQAFIDSFRKVEHWFGDYAQRFQSESRVLLRQANDNRQ
What are the official names of this protein?
T-protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the prephenate/arogenate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPI_MESMA
Sequence: MKFVFASFALFVIFLCFSQSLSQSYFRCRDNEVFDNCISNCGPPRCSNILNTYPCTNLGPLCTPGCKCKDGRVYDNQGRCVLQTECFQK
What is the function of this protein?
Serine protease inhibitor.
What are the official names of this protein?
Venom peptide BmKAPI, Ascaris-type protease inhibitor, BmAPI, Putative anticoagulant peptide BmAP1.
What is the protein family that this protein belongs to?
Belongs to the serine protease inhibitor-like (TIL domain-containing) family.
What are the subcellular locations of this protein?
Secreted.
Protein: DGTL1_MYCBP
Sequence: MSASEHDPYDDFDRQRRVAEAPKTAGLPGTEGQYRSDFARDRARVLHSAALRRLADKTQVVGPREGDTPRTRLTHSLEVAQIGRGMAIGLGCDLDLVELAGLAHDIGHPPYGHNGERALDEVAASHGGFEGNAQNFRILTSLEPKVVDAQGLSAGLNLTRASLDAVTKYPWMRGDGLGSQRRKFGFYDDDRESAVWVRQGAPPERACLEAQVMDWADDVAYSVHDVEDGVVSERIDLRVLAAEEDAAALARLGEREFSRVSADELMAAARRLSRLPVVAAVGKYDATLSASVALKRLTSELVGRFASAAIATTRAAAGPGPLVRFRADLQVPDLVRAEVAVLKILALQFIMSDPRHLETQARQRERIHRVAHRLYSGAPQTLDPVYAAAFNTAADDAARLRVVVDQIASYTEGRLERIDADQLGVSRNALD
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 2 subfamily.
Protein: COX41_SAISC
Sequence: SVVKSEDYARPSYVDRRDYPLPDVAHVRHLSASQKALKEKEKASWSSLSMDEKVEKTVVGAAMFFIGFTAILVILEKRYVYGPLPHTFDKEWVAMQTKRMLDLKMNPIDGLASKWDYEKKEWKK
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial, Cytochrome c oxidase polypeptide IV, Cytochrome c oxidase subunit IV isoform 1, COX IV-1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase IV family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: TRXB_BUCAP
Sequence: MELKNHKKIIILGSGPAGYTAAIYSSRANLNPLLITGINKGGQLMNTNEIENWPGDFKKITGPELMNRMHEHSLKFKTEIVYDNIISVEFKKKPFFLLGEYNKYTCDAVIIATGANPRYLGLSSENKFKGKGISTCAVCDGFFYKNKEIAVVGGGNTAIEETLYLSNFVKKIYLIHRRNNFKAEKILIDRLLKIVKTKKVILHLNSTIEDILGNNKGVTHLLIKNKNLKEKKKLKIAVSGLFVAIGYIPNTDIFTDQLKMKDGYIKIKKGTHGNYTQTNIPGVFAAGDVIDHVYRQAITSSASGCMAALDSERYLNSLS
What are the official names of this protein?
Thioredoxin reductase, TRXR.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRCB2_PROMA
Sequence: MFDGLSTYKSFFLVAFGAVPGAICRMKISDNLFRNKHNLWGILLVNSSACLLLGFFLAKQNYIHYINNDQPLYLLLCVGFLGSFSTFSSLILEIYYLFVDQQWMELFLFTFTSIGLGIIFISLGSHLFNA
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 2.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SURA_BLOPB
Sequence: MKFWKIFILIFTLKTNIVLGALKTVDKIVALVNHNIILDSDIRHNIYMIQDNILNGNDNILQDISHYQKILDQLIIDNLIFQISDQQKINIDHTQLNQMINCILNLYDMTFDKFRAYLYDIGLNYEKFYFQQYQHMLKKQICDHVMHDRAHILTNEINKIVKKSNIIDINKQFKLRHITFSLPIQPTPSQIDRIEYFARLLIKKKEFNNNIKELIRTYSNKNIIQIIKVHETEWVSWKDIPIIFDKYLQTINKGDVIGPIISCDGIHIVEIQDIRYKQIMLPVTKVTAKIFGIQNSCENISIVEQLLQIKENMEKSNTAFNMMIKEKSKDICFNHYEENTICKDLDDFEPSIRKALSSLKSNEISIPVHTSCGWRLIQLIDISILEYNEIMYERAYLYLLNNKFDEIMKNWIQELRSESYIKIIN
What is the function of this protein?
Chaperone involved in the correct folding and assembly of outer membrane proteins.  Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins.  May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
What are the official names of this protein?
Chaperone SurA, Peptidyl-prolyl cis-trans isomerase SurA, PPIase SurA, Rotamase SurA.
What are the subcellular locations of this protein?
Periplasm. Note=Is capable of associating with the outer membrane.
Protein: NADK_SHEDO
Sequence: MGINSDVSRPRARSTPNMSKKFQTIGLIGKPHHQGTNQTIEKLHLWLTAQGYTVLVEERVSAELEIEFQAVDLVEIGERCDLAIVVGGDGNMLGAARVLARYDVAVIGVNRGNLGFLTDLPPDGFETQLAQVLGGEFETEHRFLLEAEVHRHGMIKASNTAVNEAVLHPGKIAHMIQFEVYIDEQFMYSQRADGMIVSTPTGSTAYSLSAGGAILTPNLQALILVPMFPHTLSCRPIVVDACSTIKLVVSPDNGENLEVSCDGHVHLSVLPGDEIIIRRSQQRLMLIHPKGHNYFHVLRNKLGWGSKLF
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPR2I_MOUSE
Sequence: MSYQQQQCKQPCQPPPVCPPKKCPEPCPPPQCPEPCPPPKCPEPCPESCPPPSYQQKCPPVQPPPPCQQKCPPKSK
What is the function of this protein?
Cross-linked envelope protein of keratinocytes.  It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase.  All that results in the formation of an insoluble envelope beneath the plasma membrane (By similarity).
What are the official names of this protein?
Small proline-rich protein 2I.
What is the protein family that this protein belongs to?
Belongs to the cornifin (SPRR) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RT18C_MOUSE
Sequence: MAALVALCSGIGRKNLTTAAGCFTDRGTQAVSVIWRRCFSQFEQVTSNEDLPVPMENPYKEPLKKCVLCEKRVDYKNVQLLSQFISPFTGCIYGRHITGLCGKKQREITKAIKRAQKMGFMPVTYKDPAYLKDPRVCNIRYRE
What are the official names of this protein?
28S ribosomal protein S18c, mitochondrial, MRP-S18-c, Mrps18-c, S18mt-c, 28S ribosomal protein S18-1, mitochondrial, MRP-S18-1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: EX7L_NITEU
Sequence: MTDHNLLPEPKKILWRVSELNRNARVILEQTFPLLWVSGEISNLKRYPSGHWYFSLKDDSAQVRCVMFRHKNLYLDWIPQEGMQVEAQALVTLYEARGEFQLTVEQLRRAGLGALFEAFERLKARLQQEGLFSPEYKQPLPRFPRQIGIITSPNTAALRDVLTTLQLRLPSIPVVIYPAPVQGEGSAAAITTALHTAAVRGECDVLILCRGGGSIEDLWAFNEEIVARAIAACPIPIVTGIGHETDFTIADFVADARAPTPTGAAQLASPDRQAILHRLQYWLHRLQQTMERHIERRMQATDLLAHRLIHPGERIRHQQMHLLQLRGRLQNAWNRQVEIRTWRIEETGRRIHSAKPDIQAGIRHQQELAARLQRAMAHRLENLQFKLRQQQQHLIHLDPKAVLARGYSIAYTARGDILHDSRQTRAGDNVRLVFASGWAKADITETGE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LMTK1_HUMAN
Sequence: MSSSFFNPSFAFSSHFDPDGAPLSELSWPSSLAVVAVSFSGLFAVIVLMLACLCCKKGGIGFKEFENAEGDEYAADLAQGSPATAAQNGPDVYVLPLTEVSLPMAKQPGRSVQLLKSTDVGRHSLLYLKEIGRGWFGKVFLGEVNSGISSAQVVVKELQASASVQEQMQFLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRVAESMAPDPRTLQRMACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKIGDYGLAHCKYREDYFVTADQLWVPLRWIAPELVDEVHSNLLVVDQTKSGNVWSLGVTIWELFELGTQPYPQHSDQQVLAYTVREQQLKLPKPQLQLTLSDRWYEVMQFCWLQPEQRPTAEEVHLLLSYLCAKGATEAEEEFERRWRSLRPGGGGVGPGPGAAGPMLGGVVELAAASSFPLLEQFAGDGFHADGDDVLTVTETSRGLNFEYKWEAGRGAEAFPATLSPGRTARLQELCAPDGAPPGVVPVLSAHSPSLGSEYFIRLEEAAPAAGHDPDCAGCAPSPPATADQDDDSDGSTAASLAMEPLLGHGPPVDVPWGRGDHYPRRSLARDPLCPSRSPSPSAGPLSLAEGGAEDADWGVAAFCPAFFEDPLGTSPLGSSGAPPLPLTGEDELEEVGARRAAQRGHWRSNVSANNNSGSRCPESWDPVSAGGHAEGCPSPKQTPRASPEPGYPGEPLLGLQAASAQEPGCCPGLPHLCSAQGLAPAPCLVTPSWTETASSGGDHPQAEPKLATEAEGTTGPRLPLPSVPSPSQEGAPLPSEEASAPDAPDALPDSPTPATGGEVSAIKLASALNGSSSSPEVEAPSSEDEDTAEATSGIFTDTSSDGLQARRPDVVPAFRSLQKQVGTPDSLDSLDIPSSASDGGYEVFSPSATGPSGGQPRALDSGYDTENYESPEFVLKEAQEGCEPQAFAELASEGEGPGPETRLSTSLSGLNEKNPYRDSAYFSDLEAEAEATSGPEKKCGGDRAPGPELGLPSTGQPSEQVCLRPGVSGEAQGSGPGEVLPPLLQLEGSSPEPSTCPSGLVPEPPEPQGPAKVRPGPSPSCSQFFLLTPVPLRSEGNSSEFQGPPGLLSGPAPQKRMGGPGTPRAPLRLALPGLPAALEGRPEEEEEDSEDSDESDEELRCYSVQEPSEDSEEEAPAVPVVVAESQSARNLRSLLKMPSLLSETFCEDLERKKKAVSFFDDVTVYLFDQESPTRELGEPFPGAKESPPTFLRGSPGSPSAPNRPQQADGSPNGSTAEEGGGFAWDDDFPLMTAKAAFAMALDPAAPAPAAPTPTPAPFSRFTVSPAPTSRFSITHVSDSDAESKRGPEAGAGGESKEA
What is the function of this protein?
May be involved in neuronal differentiation.
What are the official names of this protein?
Serine/threonine-protein kinase LMTK1, Apoptosis-associated tyrosine kinase, AATYK, Brain apoptosis-associated tyrosine kinase, CDK5-binding protein, Lemur tyrosine kinase 1, p35-binding protein, p35BP.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Cytoplasm. Cytoplasm, perinuclear region. Note=Predominantly perinuclear.
Protein: DLHH_SALTY
Sequence: MTTTHPSGFAPAASPLAPTMIHTPDGAISAGITSIPSQGDDMPAYYARPKASDGALPVVIVVQEIFGVHEHIRDICRRLALEGYLAIAPELYFREGDPNDFADIPTLLSGLVAKVPDSQVLADLDHVASWASRNGGDAHRLMITGFCWGGRITWLYAAHNPQLKAAVAWYGKLVGDTSLNSPKHPVDIATDLNAPVLGLYGGQDTSIPQESVETMRQALRAANAKAEIVVYPDAGHAFNADYRPGYHEASAKDGWQRMLEWFAQYGGKKG
What are the official names of this protein?
Putative carboxymethylenebutenolidase, Dienelactone hydrolase, DLH.
What is the protein family that this protein belongs to?
Belongs to the dienelactone hydrolase family.
Protein: PAN1_HALVD
Sequence: MMTDTVDDVDLPYDKDSASQQEKITALQERLEVLETQNEEMRDKLLDTNAENNKYQQKLERLTHENKKLKQSPLFVATVQEITDEGVIIKQHGNNQEALTEVTDEMREELEPDARVAVNNSLSIVKRLDKETDVRARVMQVEHSPDVTYEDIGGLEEQMQEVRETVEMPLDRPEMFAEVGIDPPSGVLLYGPPGTGKTMLAKAVANQTNASFIKMAGSELVHKFIGEGAKLVRDLFEVARENEPAVIFIDEIDAIASKRTDSKTSGDAEVQRTMMQLLAEMDGFDERGNIRIIAATNRFDMLDPAILRPGRFDRLIEVPKPNEDGREIIFQIHTRKMNVSDDVDFVELAEMADNASGADIKAVCTEAGMFAIRDDRTEIFMQDFVDAWEKIQQEASDETEVSRAFA
What is the function of this protein?
ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle.  Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis.  Thus, the C-terminus of the proteasomal ATPase functions like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.  Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates (Probable).  Is also able to cleave other nucleoside triphosphates including GTP and TTP, but the rate of hydrolysis is 4- to 5-fold slower than for ATP.
What are the official names of this protein?
Proteasome-activating nucleotidase 1, PAN 1, Proteasomal ATPase 1, Proteasome regulatory ATPase 1, Proteasome regulatory particle 1.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm.