PharMolix/UniProtQA huggingface dataset:
Protein: SSG4_ORYSJ
Sequence: MSHCLRASPFLSPPPPLLHPSRRRRHRQGGCIHTSPGTRPLVARARFDPPPLLRLKVSDSSDCPAPHHPHSQHQPLLPTRRQQQQPPPPYQALVASLAPLWREGLFLVRCSVFAAALSVAAALSWYAQLRARSFVESRLLPAACAALGEFLQREVHLGRVRSVSPLGITLHTCSIGPHAEEFSCAEVPVMKIRVRPFASLRRGRVVVDAVLSEPSALVAQRKDFSWLGLPAPSEGSPKRHSGEEGIDYRTKTRRLAREKAAEQWNEERDKAAREAAEMGYIVPSAQSISPSIDEMMEDDGPVDTGKSSPHLCPDEMHRKDHHIDAGIDSSSKHADLEKSFGVKARIPGISFWSRMIPNPSRRRYRRKAHSKLISDTDNSSQQRILRRSAYAAVAYFQNECSGNPDDSLPGPGESSSDGGHTNGGGEEGSPNDGPTEYSETTSMDYGELPPEKSNFASTMLIGNTDVLNGSSHNQQPSQISSHSWENNEQVSEAPVLKKRKNISEDDYRQEFDFGAFGSCTYAHNWLSFWPFQLKGFPVGFNAPSASLNVQIQKLRSLFAIGPGDNSAELSQGVGQIHPGAVQQTLPITLDSVYFNGGNLMLLGYGDQEPREMKHANGHIKFKNSYNRVHVHVTGNCMEWRQDRTSQGGGYLSTDVFVDIAEQTWHANLNVVNAFAPLFERILEIPVVWNKGRATGEVHLCMSKGDSFPSIHGQLDVKGLAFQILDAPSSFSDIVATLSFRGQRVFLHNASGWFGDAPVEASGDFGLNPEDGEFHLMCQVPSVEVNALMKTMKMRPLMFPLAGAVTAVFNCQGPLDAPVFVGSGIVSRKSLSVSGMLPSAASEAVMQNKESGAVAAFDHIPFTHVSANFTFNLDNCVADLYGIRACLLDGGEIRGAGNVWICPEGEGDDSAMDINLSGSILLDKVLHRYIPGGIQLIPLKIGELNGETRLSGSLIRPKFDIKWAAPNAEDSFSDARGNIVIAHDYIMVNSSSVSFDLNTHIQTSYIDDYLLHKEMYQRKKIMPLIVEGVDLDLRMRGFEFAHIASSIPFDSPRPLHLKASGRFKFQGKVVKYSQLVDEKNHGAIQGTIDQSKLENDVSRLVGEISLSGIKLNQLMLAPQSTGFLSISPDSIMLNATGRPDENFSIEVNVPLFFGTHEAIQDGRLLSIFLQKGQLRSNICYHPENLTSLEVRNLPLDELEFASLRGFVQKAELQLNFQKRRGHGLLSVIRPKFSGMLGESLDIAARWSGDVITMEKSVLEQANSKYELQGEYVFPGTRDRFPMESQSNGFIEKAMGGHLGSMMSSMGRWRMRLEVPGAEVAEMLPLARLLSRSTDPAIRSRSKELFMQTLHSVGFNAESLRDQLKALEMYPDWLDDDTIEDITLPGLAELRGYWRGSLDASGGGNGDTMADFDFNGEDWEWGTYKTQRVLASGSFSNNDGLRLDKLFIQKDNATLHADGSILGPLTNLHFAVLNFPVGLIPALVQAIESSTTDSIHFLRQWLTPIKGILHMEGDLRGTLAKPECDVQIRLLDGTIGGIDLGRAEVLASVTPTSRFVFDANFEPTIQSGHVNIQGSVPVTYVDSNSIEEDLEGGDGKQGIIRIPVWAKDRGLTNDISETRIMRDKPDEGWEFQLAESLKGLSWNMLEPGEVRINADIKDGGMTLITALSPYSNWLQGYAEVLLQVKGTVDHPVVDGSASFHRATVASPFLRTPLTNFAGNVHVISNRLCISSMESRVGRKGRLSMKGTLPLHNIEPSANDKIELKCEVLDIRAKNILSGQVDSQLQVTGSILRPDVSGMIRLSHGEAYLPHDKGNGAVATRLSSNKSISVPAGFDQRTVSRDVSHFLGSLSTSPDGQQSETERTPEHGSFKPNIDARLNDLKLTFGPELRIVYPLILNFAVSGDLELNGMVHPKYIRPKGVLTFENGEVNLVATQVRLKNDHLNVAKFEPDLGLDPILDLVLVGSEWQFKIQSRASMWQDNLVVTSTRSVDQDVLSPSEAAKVFESQLAESLLEGDGQLAFKKLATATLETLMPRIEGKGEFGQARWRLVYAPQIPSLLSVDPTVDPLKSLANNISFATEVEVQLGKRLQASVVRQMKDSEMAMQWSLIYQLTSRLRVLFQSTPSNRLLFEYSATSQG
What is the function of this protein?
Part of the inner chloroplast membrane translocon complex (TIC) which associates with the outer chloroplast membrane translocon complex (TOC) and forms a supercomplex involved in protein precursor import into the chloroplast stroma (By similarity).  Required for the regulation of starch granule size in amyloplasts (PubMed:24335509).
What are the official names of this protein?
Protein SUBSTANDARD STARCH GRAIN 4, chloroplastic, Translocon at the inner-envelope- membrane of chloroplasts SSG4.
What is the protein family that this protein belongs to?
Belongs to the TamB family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Single-pass membrane protein. Plastid, chloroplast intermembrane space. Plastid, chloroplast. Plastid, amyloplast.
Protein: NH213_CAEEL
Sequence: MSSTPSTSDTSSESSTSPATIVLCKVCALSAHGSHFGVLACRACAAFFRRTVVLERQKQYKCKKGKNECPVDTAERYQCRLCRYNKCVDLGMTPENVQFNRESASRTRKRKNENSIAQTNSFKLIPRSDNAFLGKPRTIMDISSLSTKIKSVLNGKTYNLDSAAKKMNSLEAAEYALKKWRSQQKTEDKMEKVGELPVRQLFVIFEKQMVMIAEWLIHNPDFRMLDEEEKYLYFKAVWNMWRRFERFEMSVKMFGNQVLTKRKFAISNEKLMVMDSCIDYSEITDLPNSKVAEMFRLTRSKLFHQLAKPLMELNPSSIEMAYMLTQLSWQIAGKKMQGNVIEIGERVCDNLADDLHSYYQKNEKRSNYAGRLVRLMNIVNAMKKIHLQRKNTMELARIFEMFKVDFSDPDIFDC
What is the function of this protein?
Orphan nuclear receptor.
What are the official names of this protein?
Nuclear hormone receptor family member nhr-213.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family.
What are the subcellular locations of this protein?
Nucleus.
Protein: STAC_MOUSE
Sequence: MIPPSGAREDSGDGLTGEATGTEQPPSPASTSSLESKLQKLKRSLSFKTKSLRSKSADNFFPRTNSDVKPQADLLAKASPGPSPIAIPGSPASMPTKAGLHPGSNSKLHAFQEHVFKKPTFCDVCNHMIVGTHAKHGLRCGACKMSIHHKCADGLAPQRCMGKLPKGFRRYYSSPLLIHEQFGCIKEVMPIACGNKVDPVYEALRFGTSLAQRTKKGGSGSGSDSPPRTSTSELVDVPEEADGPGDGSDMRTRSNSVFTYPENGMDDFRDQMKTTNHQGPLSKDPLQMNTYVALYRFIPQENEDLEMRPGDMITLLEDSNEDWWKGKIQDRVGFFPANFVQRVEEHEKIYRCVRTFIGCKDQGQITLKENQICVTSEEEQDGFIRVLSGKKRGLVPLDVLVDV
What is the function of this protein?
Promotes expression of the ion channel CACNA1H at the cell membrane, and thereby contributes to the regulation of channel activity (PubMed:27149520).  Plays a minor and redundant role in promoting the expression of calcium channel CACNA1S at the cell membrane, and thereby contributes to increased channel activity (PubMed:29467163).  Slows the rate of calcium-mediated inactivation of CACNA1C calcium channel activity (PubMed:29363593).
What are the official names of this protein?
SH3 and cysteine-rich domain-containing protein, Src homology 3 and cysteine-rich domain-containing protein.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side.
Protein: ILVD_PSEA6
Sequence: MPKLRSATTTQGRNMAGARALWRATGMKDGDFGKPIIAVSNSFTQFVPGHVHLKDMGQLVARSIEAAGGVAKEFNTIAVDDGIAMGHSGMLYSLPSREIIADSVEYMVNAHCADAIVCISNCDKITPGMLMASMRLNIPVIFVSGGPMEAGKTKLSDQIIKLDLVDAMVAGVDNNVNDEQSGEIERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSMLATHADREGLFKQAGTQIVELCRRYYQQDDESVLPRNIANFKAFENAMSLDIAMGGSTNTILHLLAAAVEGEVPFTLDDIDRLSRNVPHLCKVAPSTPQYHMEDVHRAGGVLGILAELNRAGLLHEDTPHVLGKSIGEVISEWDITQPENAHALEFFRAGPAGIRTTKAFSQDCRYPTADTDRENGCIRSRANAFSEEGGLAVLFGNIAQDGCIVKTAGVDESIHVFTGRARIYESQDDAVKAILADEVIAGDIVVIRYEGPKGGPGMQEMLYPTTYLKAKGLGKKCALITDGRFSGGTSGLSIGHCSPEAASGGGIGLVEEGDSMTIDIPQRKIGVDISDEVLQARREKMEQSANPWKPVSRERKVSLALKAYALLATSADKGAVRDASKLED
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: RIBA_ARCFU
Sequence: MEEVSSHVKSGKPVMILDSEKSAICIPAEVVSGEILNFMMKNCDEIRLALTWKQILNLGLNRFRFQNGNLIPIDPNLEKISAEERAKFIRELVSGNAGDIKYPGRIFVEETKEMGVLERPGIAEACVDLARMAGFAPSAVYAPLMTAEGGVAGEDYALKFAKEHSMPVFRIKDMIEFRIKSEKIVERVIEATLPTKFYGTFRAVGYKTPLGEIVALVKGRVDEGDVLVRIHSECLTGDVFHSLRCDCGDQLENALKMIDREGKGVAIYMRGHEGRGIGLINKLMAYKLQEEGKDTVDANIELGFPPDMRSYGIAAQILMDLKVKSIRLLTNNPLKIEELKKYGFKIVREPIEVEPCEVNLPYLKAKKDKMGHLICFND
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the GTP cyclohydrolase II family.
Protein: ASGX_DICDI
Sequence: MNKKSVLVIHGGAGVISKSTISKEREEIFLNSLKNILLAGKIILKQGGTSLDVVQEAVRLLEEDPIYNAGKGSVFTELGTNEMDAAIMDGTNLKAGAVGGVSIIRNPIIAARAVMEHTNHCLLVGKGAEEFAKSKNLEIVEPSFFFTQNRYDQLLRAKDEKKLILDHDGENLLEKEKEKEKNNETSTTTTTISVGVDPIDPKYKMGTVGAVCLDSFGNLAAATSTGGMTNKMHGRVGDTPIIGAGVYANKNVAVSSTGTGEAFMRTVAAFDIAAMMEYGSLSLKDASNKVVMEKLITVGDGGVICVDKYGNVEMPFNTEGMYRGYVIIDNNCENDQNDIINVSIYK
What is the function of this protein?
Has both L-asparaginase and beta-aspartyl peptidase activity.  Does not have aspartylglucosaminidase activity and is inactive toward GlcNAc-L-Asn.  Likewise, has no activity toward glutamine (By similarity).
What are the official names of this protein?
Putative isoaspartyl peptidase/L-asparaginase, Beta-aspartyl-peptidase, Isoaspartyl dipeptidase, L-asparagine amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the Ntn-hydrolases family.
Protein: PR4_PRUPE
Sequence: QNINWDLRTASVFCATWDADKPLSWRSKYGWTAFCGPVGPTGQDSCGKCLLVTNTGTGAKVTVRIVDQCSNGGLDLDVNVFNQIDTNGQGNAQGHLIVNYDFVDCGD
What is the function of this protein?
May be involved in protecting plant tissues from pathogen infection.
What are the official names of this protein?
Pathogenesis-related protein PR-4, PpAz89.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: AROA_SALPC
Sequence: MESLTLQPIARVDGAINLPGSKSVSNRALLLAALACGKTVLTNLLDSDDVRHMLNALSALGINYTLSADRTRCDITGNGGALRAPGALELFLGNAGTAMRPLAAALCLGQNEIVLTGEPRMKERPIGHLVDSLRQGGANIDYLEQENYPPLRLRGGFTGGDIEVDGSVSSQFLTALLMTAPLAPKDTIIRVKGELVSKPYIDITLNLMKTFGVEIANHHYQQFVVKGGQQYHSPGRYLVEGDASSASYFLAAGAIKGGTVKVTGIGRKSMQGDIRFADVLEKMGATITWGDDFIACTRGELHAIDMDMNHIPDAAMTIATTALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDYIRITPPAKLQHADIGTYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQLARMSTPA
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BRLA_METRA
Sequence: MQFESDFRFDMDDSFSMCSQTLPCPSAGSSFSSASSAYEPFTPTSRRSTPNELSLDFEGAYNPFATHHSELTSPSGHMSKYMFGGPVKGEPEHMSFNEALPTTPMKKLDGMVTPDYDHMLEMNLASRHSIGSITPSGSFPMYTISPTTMGPTSFMMTPTHSLSGSEIAESTSSWSCSNESPISFFPQRGLGPLELEGLDMDRHPQSPLGTYHLHAPPSPGRLRAHRKMMVHEIQRKTNELQRAQIRASRKVSGSKSDGGVDVVRRAMCKCDYPGCHKAFRRNEHLKRHKQTFHGEGPNRFSCEFCGKDQFNRQDNLNNHRKLHARPNSRNRGVEFIPAAVPIIEQEERSRKRRAPPKSKSADKRVDDY
What is the function of this protein?
BrlA, abaA and wetA are pivotal regulators of conidiophore development and conidium maturation.  They act individually and together to regulate their own expression and that of numerous other sporulation-specific genes (PubMed:29958281).  BrlA, abaA and wetA act together to positively regulate the expression of the Pks1 gene cluster that mediates the biosynthesis of an anthraquinone derivative pigment that contributes to conidial pigmentation that provides protection from UV radiation, heat and cold stress (PubMed:29958281).
What are the official names of this protein?
C2H2 type master regulator of conidiophore development BrlA.
What are the subcellular locations of this protein?
Nucleus.
Protein: SEY1_PICST
Sequence: MSQSSPSNAETDEDLSTTSSSSSFVPIEQHQIQDAIQVIDENKEFNKNILPYVVKTTPISSVGNNYHIISVFGSQSTGKSTLLNRLFNTNFDVMDESRRQQTTKGIWMAHSPQVSTTKQMDTHQENIFVMDVEGTDGRERGEDQDFERKAALFALATSEILIVNIWETQIGLYQGANMGLLKTVFEVNLTLFGKSKLEKNDHKVLLLIVIRDHVGLTPKENLSSTITQDLLKIWESLNKPAELAHLQFEDFFDTDFHTLRHKVLQPKEFLEDVNELGDRLVVKKDLFRPNYHHNIPIDGWTMYAENCWQQIDSNKDLDLPTQQILVAKFKCDEISASVYEEFHQKFKAISSANTPGISTLDYQDLGLLLVDLRSDTLENYDLSASRYTKSVYEQRKDLLKEKLNEKFREFFDAHIKHLSEKSVKEFETNIVGLKGKNFDKEATRLTRETTDYFINSAILLSLENELDYDVHVSNLQDQLTKLIQQQQLVELKNIVNKSIKKLSSGLTKAVSFELADPTETSWNNILSKFKEFVLDFLSKNELEEEAGTYDFGLGTNRAQNKEAVETFKFKSWNAFYEIIHKIISKDNLLTLLKDRFDDKFRYDENGLPRMYQNTVELETNFGISKSFALRIVPLLTIAKLNDNSEILPDYDIFDSKLRAKYLGLVENEHDSEDEEDEEDRCFAEIISESEKAEVLNKFKKETDARFIETKRSIVQHVTQIPYYIYLVIMVLGWNEFMAIVRNPLFFSLVLVFGAGLYILYSMNLLKPAMVVVQRLIDEIIAMAKEKMREFLIDDHPTQAHNLQKISASNREKVEEEKVVETIEMQDL
What is the function of this protein?
Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network.  Has GTPase activity, which is required for its function in ER organization.
What are the official names of this protein?
Protein SEY1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Enriched in the cortical ER. Concentrated in punctae along the ER tubules.
Protein: SYV_TROW8
Sequence: MNIPDKPSLEGLEEKWSKLWKSSKIYNFELEQVSAKQDVYSIDTPPPTASGVLHIGHVFSYTHTDIIARFQRMQGKIVFYPMGWDDNGLPTERRVQNYFSVRCDPSLPYCQNLKLAQINNDSMARSISRRNFIELCQQLSEEDERKFEELWNYLGLSVDWSQTYRTIDDDAIHLSQHFFLENVNSGAAYQDWAPTLWDVTYRTAVAQAEIEERQITGFYYRLAFENENATVEIETTRPELLAGCVALVAHPDDNRYKHLFGSHVITPVFDVKVPVLPHRAAQPDKGSGIAMVCTFGDITDVQWWRDLNLQSCPIIDASGRVVPDAPDPIVSERGRRAFATLSGKTLSAAKKHTLEMLISEKSIIGEPRKITHPVKFFEKGDKPLEILLTRQWYIRNGYSDNALTERLIELGKQLQWYPKTMLRRYEDWLTGLNSDWLISRQRFLGVPFPIWYQTDDRGNAKFDDPIFPDRKDLPLDPTIAVPRGYSENQRGAPNGFVAETDVMDTWATSSLTPQLAGKYLKNPKLFEAIFPYSLRPQGQDIIRTWLFSSIIRSEYAHATAPWKSTAISGFILDPDRKKMSKSKGNAKTPKDILDRYGADAVRYWAACARLGVDTALDVENPTQIKIGRRLALKVLNAARFVVHLHKNKETYSGQPDMKRCYPIDFAAISNPLDLSLLKQLDQTIEQSTNALKNFDHSKALDTTETFFWNFCDNYVEIVKDRAYAGDESALTTLLVVTNIVIKLLAPFIPYATEEAWSWFNETSVHTQSWPETLKLHSGDIELLKIACSFMSLVRGGKTEAKLSQKTEIAYLKIALPNPEIIMPIMDDLRRAGKIDKCELIDGDAQILAIEYGEISR
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CMPD_SYNE7
Sequence: MQTLRQQQPIVPSSPGHDPFLIVENVSKIYETPKGPYTVLDGVNLTVQEGEFICVIGHSGCGKSTLLNMVSGFNQPSHGSVRLKGKEIDRPGPDRMVVFQNYALLPWMTAYENVYLAVDCVNPQMREGEKREIVREHLAMVGLTEAAEKKITQISGGMKQRVAIARALSIRPEVLILDEPFGALDAITKEELQEELLKIWNDHRCTVLMITHDIDEALFLADRLVMMTNGPAANIGEIMTIPFPRPRDRERIMEDPQYYDLRNYALDFLYNRFAHDDE
What is the function of this protein?
Part of the ABC transporter complex CmpABCD involved in bicarbonate transport.  Responsible for energy coupling to the transport system (Probable).
What are the official names of this protein?
Bicarbonate transport ATP-binding protein CmpD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Nitrate/nitrite/cyanate uptake transporter (NitT) (TC 3.A.1.16) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: JAL40_ARATH
Sequence: MAQKLEAIGRGLQWDDSSDHDNVTKILVRGGREGIQYVKFDYVKSGQPQTGLIHGLSGRGGFTQTFEIDQKDEHLVSVEGYYDVTKGVIQALKFKTNKKTSEMIGYDDTGIKLSLEVKGKKIIGFHGYAETNLNSLGAYFTTTGPIGLNPQVGHIKLAYQGGGGGIPWDHGPNHNGVKRVSFIFDENEIRQWRVDYDDGGVIRQYEPINGYDMFEVKEYPTEYIISVECTYDDVIPRSGRRMIRSIMFKTSKGRVSPIFGYPAARKFVLENNGGALIGFHGRVGAGIDALGAYFSSFIPSPPPPSPEKLQPEGGEAVGDPWDDGIFNGVREIHLEDGEGIALKFVYDKDVQVTELKVHGEPSGIGFNEFKLDYPSEYITTVEGFWDKTSGNERGVITRLRFTTNKQTFRPVGLESTTSFSLGKEGYKIVGFHGNSSTDKLHQLGVYVVPITRE
What are the official names of this protein?
Jacalin-related lectin 40.
What is the protein family that this protein belongs to?
Belongs to the jacalin lectin family.
Protein: AGO3_HUMAN
Sequence: MEIGSAGPAGAQPLLMVPRRPGYGTMGKPIKLLANCFQVEIPKIDVYLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA
What is the function of this protein?
Required for RNA-mediated gene silencing (RNAi).  Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them.  Proposed to be involved in stabilization of small RNA derivates (siRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent siRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4.  Possesses RNA slicer activity but only on select RNAs bearing 5'- and 3'-flanking sequences to the region of guide-target complementarity (PubMed:29040713).
What are the official names of this protein?
Protein argonaute-3, Argonaute3, hAgo3, Argonaute RISC catalytic component 3, Eukaryotic translation initiation factor 2C 3, eIF-2C 3, eIF2C 3.
What is the protein family that this protein belongs to?
Belongs to the argonaute family. Ago subfamily.
What are the subcellular locations of this protein?
Cytoplasm, P-body.
Protein: KEFG_SALDC
Sequence: MSQPAKVLLLYAHPESQDSVANRVLLKPAIQHNNVTVHDLYARYPDFFIDTPYEQALLREHDVIVFQHPLYTYSCPALLKEWLDRVLSRGFASGPGGNQLVGKYWRSVITTGEPESAYRYDALNRYPMSDVLRPFELTAAMCRMHWMPPIIVYWARRQSPQTLASHAKAYGEWLANPVSAGGY
What is the function of this protein?
Regulatory subunit of a potassium efflux system that confers protection against electrophiles.  Required for full activity of KefB.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system ancillary protein KefG, Putative quinone oxidoreductase KefG.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL6_PICTO
Sequence: MIKWTEQAEIKLPDDVQATMENNELKIKGKLGEASRIFRDNYVKAYIEGSSVKIATSKNNKYTKGIVGTWYSETKLLIEGVTKGFEYHMKIDFTHFPMRVSVRGDKLIVENFLGEKSPRSAKIVDGCKVSVKGDRITINGIDKRKIGETAANIERATYIRHFDARVFQDGIFLLKGEVNE
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: HIS1_SALSV
Sequence: MLDNTRLRIAIQKSGRLSDDSRELLARCGIKINLHTQRLIAMAENMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYFTLRRLDFGGCRLSLATPVDEAWDGPAALDGKRIATSYPHLLKRYLDQKGVSFKSCLLNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMAQSKQELIDKLLTRIQGVIQARESKYIMMHAPSERLEEVIALLPGAERPTILPLAGEQQRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_PROM1
Sequence: MKEGPISSSSNFNHVPVMGKEIIQSLKELPSELTKQGLIIDATIGGGGHSAQILENFPGIKIIGLDQDPMAREAASKKLIKFGTRIKIISTNFADFSLDEQAICVLADLGVSSHQLDEPSRGFSFRLNGPIDMRMNPKEGSSAAELIETLSEQNLADLIYELGEEKRSRRIARKIKNDLAENGPYSGTQDLSYAIAGCFPPKQRYGRIHPSTRTFQALRIAVNNELGSLESLLLKAPNWLLENGLFMVMSFHSLEDRRVKSSFKTDNRLKVLSKKPIRASPEEIELNPRSKSAKLRISAKKFLT
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_FRATF
Sequence: MRIILLGAPGAGKGTQAKIIEQKYNIAHISTGDMIRETIKSGLVLGQELKKVLDAGELVSDEFIIKIVKDRISKNDCNNGFLLDGVPRTIPQAQELDKLGVNIDYIVEVDVADNLLIERITGRRIHPASGRTYHTKFNPPKVADKDDVTGEPLITRTDDNGDTVKQRLSVYHAQTAKLIDFYRNFSSTNTKIPKYIKINGDQAVEKVSQDIFDQLNKR
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS_PSEF5
Sequence: MSKNTSDLSSHTPMMQQYWRLKNQHPDQLMFYRMGDFYEIFYEDAKKAAKLLDITLTARGQSAGQAIPMCGIPYHAAEGYLAKLVKLGESVVICEQVGDPATSKGPVERQVVRIITPGTVSDEALLDERRDNLIAAVLGDERLFGLAVLDITSGNFSVLEIKGWENLLAELERINPVELLIPDDWPQGLPAEKRRGVRRRAPWDFERDSAHKSLCQQFSTQDLKGFGCETLTLAIGAAGCLLSYAKETQRTALPHLRSLRHERLDDTVVLDGASRRNLELDTNLAGGRDNTLQSVVDRCQTAMGSRLLTRWLNRPLRDLKVLEARQSSITCLLDGYRFERLQPQLKEIGDIERILARIGLRNARPRDLARLRDALAALPELQEAMTELEATHLNQLAATTSTYPELAALLAKAIIDNPPAVIRDGGVLKTGYDAELDELQSLSENAGQFLIDLEAREKARTGLANLKVGYNRIHGYFIELPSKQAEQAPADYIRRQTLKGAERFITPELKEFEDKALSAKSRALAREKMLYDALLETLISHLPPLQDTAGALAELDVLSNLAERALNLDLNCPRFVSEPCMRITQGRHPVVEQVLTTPFVANDLSLDDNTRMLVITGPNMGGKSTYMRQTALIVLLAHIGSFVPAASCELSLVDRIFTRIGSSDDLAGGRSTFMVEMSETANILHNATERSLVLMDEVGRGTSTFDGLSLAWAAAERLAHLRAYTLFATHYFELTVLPESEPLVANVHLNATEHNERIVFLHHVLPGPASQSYGLAVAQLAGVPSAVITRAREHLSRLETTSLPHEVAPQAPGKPSVPQQSDMFASLPHPVLDDLAKLDLDDMTPRRALEMLYTLKTRI
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.