PharMolix/UniProtQA huggingface dataset:
Protein: IF2_LACJO
Sequence: MAKKRIYEVAKELDIENKIVVKKAQDLGFDVKSHMSSLDDKQVSKLVDSLKSTNTTPSTEKDSKNSSRKEKAKIKVSVGAIRRRDNKNEHDNRHGNNKHRNNNFKKQQNNRRENEDKKTTSAKPAARDLLNKFKKKQRAEASELNAQTEASRRKWHQEQNPQRSKVKKVENTRKPKEEKLEGAAAVKARVQASQKPVGPKIIKPSPARNKAKRPTVKKVEPIAPVVPAPQKEETKPTRKKDFTRKKREVPDYERERSEHSDKARRRRNKKNKRINQSKEVKKQPTQRKERPLPETLVYEEGMNAQDLGKLLHREPAEIVKKLFMLGVMTNQNQSLDKDTIELLAAEYGIEAEEKVHEDISDIDTLYTKEMEESKASKHQEKRPPVVTIMGHVDHGKTTLLDRLRHTNVSEHEAGGITQRIGAYQVRIDDRLITFLDTPGHAAFSNMRARGAEITDIVILVVAADDGVMPQTIEAIDHAKSAGVPIIVAVNKIDKPGANPDHVMEQLMKYGLVPEDWGGDTIFVKISAKTGKNVEELLQMILLQADVMELKADPDQKAIGTVIEARLDKGRGSVADILVQQGTLKVGDPIVVGDTFGRVRVMTNDKGRRVKKATPSTPVEITGLNDVPEAADKLVVFDDEKTARSVGEQRAKNALEKQRENVQHVTLDNLFDTMKKENMKEVDIVLKADVQGSAEALQQSLEKIEVEGVRVNIIHSGVGAINESDVTLAGASNAFIVGFNVRPTNTAKSQADSEGVDIRLYNIIYKVMDDVEAAMKGMLEPTYEEKVTGNLTVRETWKVSKIGTIAGAFVDNGYVTRDSGIRVIRDGIVKYDGKVASLKRFKDDVKEVKQGFDCGITIENFNDIKVDDQLEAYEMQEVPVK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SDRF_STAEP
Sequence: MKKRRQGPINKRVDFLSNKVNKYSIRKFTVGTASILVGATLMFGAADNEAKAAEDNQLESASKEEQKGSRDNENSKLNQVDLDNGSHSSEKTTNVNNATEVKKVEAPTTSDVSKPKANEAVVTNESTKPKTTEAPTVNEESIAETPKTSTTQQDSTEKNNPSLKDNLNSSSTTSKESKTDEHSTKQAQMSTNKSNLDTNDSPTQSEKTSSQANNDSTDNQSAPSKQLDSKPSEQKVYKTKFNDEPTQDVEHTTTKLKTPSVSTDSSVNDKQDYTRSAVASLGVDSNETEAITNAVRDNLDLKAASREQINEAIIAEALKKDFSNPDYGVDTPLALNRSQSKNSPHKSASPRMNLMSLAAEPNSGKNVNDKVKITNPTLSLNKSNNHANNVIWPTSNEQFNLKANYELDDSIKEGDTFTIKYGQYIRPGGLELPAIKTQLRSKDGSIVANGVYDKTTNTTTYTFTNYVDQYQNITGSFDLIATPKRETAIKDNQNYPMEVTIANEVVKKDFIVDYGNKKDNTTTAAVANVDNVNNKHNEVVYLNQNNQNPKYAKYFSTVKNGEFIPGEVKVYEVTDTNAMVDSFNPDLNSSNVKDVTSQFAPKVSADGTRVDINFARSMANGKKYIVTQAVRPTGTGNVYTEYWLTRDGTTNTNDFYRGTKSTTVTYLNGSSTAQGDNPTYSLGDYVWLDKNKNGVQDDDEKGLAGVYVTLKDSNNRELQRVTTDQSGHYQFDNLQNGTYTVEFAIPDNYTPSPANNSTNDAIDSDGERDGTRKVVVAKGTINNADNMTVDTGFYLTPKYNVGDYVWEDTNKDGIQDDNEKGISGVKVTLKNKNGDTIGTTTTDSNGKYEFTGLENGDYTIEFETPEGYTPTKQNSGSDEGKDSNGTKTTVTVKDADNKTIDSGFYKPTYNLGDYVWEDTNKDGIQDDSEKGISGVKVTLKDKNGNAIGTTTTDASGHYQFKGLENGSYTVEFETPSGYTPTKANSGQDITVDSNGITTTGIINGADNLTIDSGFYKTPKYSVGDYVWEDTNKDGIQDDNEKGISGVKVTLKDEKGNIISTTTTDENGKYQFDNLDSGNYIIHFEKPEGMTQTTANSGNDDEKDADGEDVRVTITDHDDFSIDNGYFDDDSDSDSDADSDSDSDSDSDADSDSDADSDSDADSDSDSDSDSDADSDSDSDSDSDSDSDSDADSDSDSDSDSDADSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDADSDSDADSDSDSDSDSDADSDSDSDSDSDADSDSDSDSDSDSDSDSDADSDSDSDSDSDSDSDSDSDSDSDSDSDSDADSDSDSDSDSDSDSDSDSDSDSDSDSDSDADSDADSDSDADSDSDADSDSDSDSDSDADSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDADSDSDSDSDSDSDSDSDADSDSDSDSDSDADSDSDSDSDSDADSDSDSDSDSDADSDSDSDSDSDSDSDSDADSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDADSDSDSDSDSDADSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDKNAKDKLPDTGANEDHDSKGTLLGTLFAGLGALLLGRRRKKDNKEK
What is the function of this protein?
Binds to type I collagen via alpha-2(I) or alpha-1(I) chains, although its affinity for the alpha-1(I) chain is significantly higher.  Involved in bacterial adherence to transcutaneous drivelines from explanted ventricular assist devices.
What are the official names of this protein?
Serine-aspartate repeat-containing protein F.
What is the protein family that this protein belongs to?
Belongs to the serine-aspartate repeat-containing protein (SDr) family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor.
Protein: METK_METTP
Sequence: MTRNIRVEELTQRPVEKQKIEVVERKGLGHPDSVADGIAEEISRALCKEYIERFGRVLHHNTDKIQIVAGRSRPAFGGGEVIQPQYILLTGRATRVCGDVEVPVDAIALRTARNHLKRALRNLDLDTHVIIDCKIGTGSADLCDIFDRDASTVPSANDTSYGVGYAPLSETERIVYSTEQELLSLRSRIPAIGEDIKVMGLREDDTIYLTIACAMVDRYIDDLDHYVETKKEIVEEISAKAQSMTRRRVDVQMNVGDNIATGSVYITVTGTSAEMGDDGAVGRGNRANGLITPNRPMSLEATSGKNPINHVGKIYNLLSNLIAKEIAEEVDGVEEVYVKILSQIGKPISQPHIASVQLVLKEGVRLSSAHARAREITDRWLEDIPRVQQMIFHGELQTY
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase 2 family.
Protein: WBPD_PSEAE
Sequence: MSYYQHPSAIVDDGAQIGSDSRVWHFVHICAGARIGAGVSLGQNVFVGNKVVIGDRCKIQNNVSVYDNVTLEEGVFCGPSMVFTNVYNPRSLIERKDQYRNTLVKKGATLGANCTIVCGVTIGEYAFVGAGAVINKNVPSYALMVGVPARQIGWMSEFGEQLQLNEQGEAVCSHSGARYVLNGKILSKVDV
What is the function of this protein?
Plays a role in the biosynthesis of B-band O antigen for serotype O5.  Catalyzes the transfer of an acetyl group to the C-3 amino position of UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucuronate (UDP-D-GlcNAc3NA).
What are the official names of this protein?
UDP-2-acetamido-3-amino-2,3-dideoxy-D-glucuronate N-acetyltransferase, UDP-D-GlcNAc3NA N-acetyltransferase, UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucuronic acid 3-N-acetyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: ATPG_PROMH
Sequence: MAGAKEIRSKIASVQNTQKITKAMEMVAASKMRKTQERMAASRPYAETMRSVIGHLALGNLEYKHPYLEEREVKRVGYLVVSTDRGLCGGLNINLFKKLLADMKEWSDKGVEVDLALVGSKAVSFFASVGGNVVGQVTGMGDDPQLSDLIGPVNIMLQAYDEGRLDKLYVVANKFINTMAQEPKILQVLPLPPGDDEELKEKSWDYLYEPDPKTLLDTLLRRYIESQVYQSVVENLASEQAARMVAMKAATDNGGNLIKELQLVYNKARQASITQELTEIVSGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MIAB_NOCSJ
Sequence: MSTAQHTSPRTYEVRTYGCQMNVHDSERLTGLLEDAGYVAAPDGQQADVVVFNTCAVRENADNKLYGNLGHLAPVKAATPGMQIAVGGCLAQKDRDTITTRAPWVDVVFGTHNIGSLPALLERARVQDEAQVEILESLEVFPSTLPTRRESAYAAWVSVSVGCNNTCTFCIVPSLRGKEKDRRPGEILAEVEALVADGVSEITLLGQNVNAYGVEFGDRQAFSKLLRACGEVDGLERVRFTSPHPAEFTDDVIAAMAETPNVMPQLHMPLQSGSDKVLRDMRRSYRQRKFLGILERVRAAMPDAAITTDIIVGFPGETEEDFLQTMHVVRAARFSGAFTFQYSKRPGTPAATLPDQVPPEVVKDRYERLVALVNEIAWEENKRLVGRRVELMVAEGEGRKDAATHRLSGRGPDNRLVHFAPPAGVEIRPGDLATVEVTYAAPHHLVADGPVVDVRRTRSGDAWAARNAAPAPSSGVTLGMPTVGAPAPLPDAPACR
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_SALRD
Sequence: MARYRGPKQKIARRFKEPIFGPSKALERKPYPPGQHGQSRRRRESEYAVQLKEKQKTKYTYGLLERQFKNLFDKASRMQGVTGEKLLILLEARLDNTVFRMGIARTRRQARQFVAHRHIMVNDEVVDIPSYEMSPDDVVSVKPSSQDLEVIQTNVEHRQRTFSWLEMDRQEMKGKFIDYPNREEIPENIDEQLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RS21_ACHLI
Sequence: MSKTEVRKGETIEDTLRRFKRTVSKDGTLVEARKREYYIKPGVDRRMKAKAAKTKKKKR
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: MCP4_ECOLI
Sequence: MFNRIRISTTLFLILILCGILQIGSNGMSFWAFRDDLQRLNQVEQSNQQRAALAQTRAVMLQASTALNKAGTLTALSYPADDIKTLMTTARASLTQSTTLFKSFMAMTAGNEHVRGLQKETEKSFARWHNDLEHQATWLESNQLSDFLTAPVQGSQNAFDVNFEAWQLEINHVLEAASAQSQRNYQISALVFISMIIVAAIYISSALWWTRKMIVQPLAIIGSHFDSIAAGNLARPIAVYGRNEITAIFASLKTMQQALRGTVSDVRKGSQEMHIGIAEIVAGNNDLSSRTEQQAASLAQTAASMEQLTATVGQNADNARQASELAKNAATTAQAGGVQVSTMTHTMQEIATSSQKIGDIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLASRSAQAAKEIKGLIEESVNRVQQGSKLVNNAAATMIDIVSSVTRVNDIMGEIASASEEQQRGIEQVAQAVSQMDQVTQQNASLVEEAAVATEQLANQADHLSSRVAVFTLEEHEVARHESVQLQIAPVVS
What is the function of this protein?
Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation.  Attractants increase the level of methylation while repellents decrease the level of methylation, the methyl groups are added by the methyltransferase CheR and removed by the methylesterase CheB.
What are the official names of this protein?
Methyl-accepting chemotaxis protein IV, MCP-IV, Dipeptide chemoreceptor protein.
What is the protein family that this protein belongs to?
Belongs to the methyl-accepting chemotaxis (MCP) protein family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Found predominantly at cell poles.
Protein: RRF_POLSJ
Sequence: MSIVEVKQNAEQKMQQSVDSFKNSLTKIRTGRANPGLLDTVHVDYYGSMVPISQVANVSLLDARTISVSPWEKGMGAKIEKAIRDSDLGLNPAAQGDLIRVPMPAMTEERRKELTKVVRAEGEHAKVAVRNLRRDANEGVKKLLKEKLVSEDDERRAQDEIQKFTDRFIAEVDKLVAGKEQDIMAV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRF_CAMJE
Sequence: MKLCVALDLSTKEECLQLAKELKNLDIWLKVGLRAYLRDGFKFIEELKKVDDFKIFLDLKFHDIPNTMADACEEVSKLGVDMINIHASAGKIAIQEVMTRLSKFSKRPLVLAVSALTSFDEENFFSIYRQKIEEAVINFSKISYENGLDGMVCSVFESKKIKEHTSSNFLTLTPGIRPFGETNDDQKRVANLAMARENLSDYIVVGRPIYKNENPRAVCEKILNKIHRKNISENDIEQNYEVIQQKEWDMCNHFEEWIKTRPDKEHALKEFYAKCGIKY
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: DGTL1_RICAH
Sequence: MLASYASDPLKSRGRLYKEIPTSYRNEFECDRDRIINTNAFRRLQYKTQVFINHEGDHYRNRLTHSLEVSTVARSVANTLNLSSDLAETIALAHDLGHTPFGHAGERALNECMKEYSGFSHNAQSLKILTLLEKRYAAYNGVNLTWEVLEGIIKHNGPITGEINEYIAEYNKQNDLELSTYASAEAQIASLADDISYISHDLEDSIGAKIIDFNSLAELKYIDQHVFELKSKFKNISSSCLIYEVVRKLMHELITDLLWQTKENLNKEKIINIYEIRHLNYQIVDFTEKTNDRIKETKKFLHERVYKSNKITAISLKCTKIVQGLFKVYMDDINLLPVNWKMLIDSDDTYSKARVIADYIAGMTDRFAIQEYNQLCSLNFNNILKLNYEYI
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 2 subfamily.
Protein: SYFA_METAR
Sequence: MDLSINERLVLRSLDLKEVTAKDLASAAGLKPEAAVQGAAMLAEKGLATLRDEVESEYVLTDEGRKYAAEGLPERVIHDALPADGITLNDLKKQFPPATVNIAMGWLRQKGWAKFEKKDGDMFLLPQKADASADEKMLAAISNGESQKGFDAKVIKDLLKRNLIELRETKTKFVKITDSGLAVKQAGIEITEEIAQLTPEMIATGSWQGKTFRKFDVSLPVQTEYGGRKHILRMGMDAVKRTLIEMGFKEMEGPMVDAEFYVNDLLFMPQDHPARTHWDQFNLKEPKYIHSLPQNLVERVRRVHRDGGSSGSLGWNYEWDETIARKLVLRGHTTSLTARYLAKHSKPPQKYFSVSQVFRNDTIDVTHLLEFCQIEGWIMDDNLSMKELMGTFKEFYSRMGITVLKFKPTYNPYTEPSLEIYGRHPKTGRWIEVGNSGMFREEMMEPYGINSTVVAWGLALERLMMINYGYTDIRDLHGPLCDINFLRSVPVVWQQ
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU2C1_CYCTA
Sequence: MKEFHLLLFHGGSIFPECILILGLILLLMIDLTSDQKDTPWFYFISLTSLVMSITVLLFRWREEPMISFLGNFQTSNFSKIFRFLILLCSTLCIPLSVEYIKCTEMAITEFLLFLLTAALGGMVLCGANDLVTIFVALECFSLCSYLLSGYTKRDVRSNEATMKYLLMGGASSSILVYGFSWLYGLSGGEIELQEVVNGLINTQMYNSPGILIALISIAVGIGFKLSLVPFHQWTPDVYEGSPTPVVAFLSVTSKVAASALATRIFDLIFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSMGQIGYIIIGIIAGDSKNGYASMITYMLFYIFMNLGTFACIVLFGLRTGTDNIRDYAGLYTKDPFSAFSLALCLLSLGGIPPLAGFFGKLYLFWCGWQAGSYLLVSIGPLMSVISIYYYLKIIKLLMTERNKEITPHVQNYRRSPSSFISKNSIELSMIVCVTASTTLGIVMNPIIAIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 A, chloroplastic, NAD(P)H dehydrogenase, subunit 2 A, NADH-plastoquinone oxidoreductase subunit 2 A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RL29_CHLTB
Sequence: MGAKKNLLAELREKSSEELDEFIRDNKKALFALRAEAALQNKVVKTHQFSLYKKSIARALIIKQEKKDRVHG
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: DSBB_ACTP2
Sequence: MLSYFKELSLNRTAWLLLAFVAFALEASAIYFQYGMGLVPCVMCVYERLAIFGLLIAGLVGAISPRFFLTRWLALLLWGFSAFKGLALAIKHHDYQANPSPWNQCEFKPEFPQTMPFDQWFPSIFAPGPVNCSEKQWEMFGLGMPEWLILAFSIFALMFVIVLLSQFKRAKPQYRSVFR
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by oxidizing the DsbA protein.
What are the official names of this protein?
Disulfide bond formation protein B, Disulfide oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the DsbB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DNAJ_PECAS
Sequence: MAKQDYYESLGVAKSADDREIKKAYKRLAMKYHPDRNPGDSEAEAKFKEIKEAYEILIDSQKRAAYDQYGHAAFEQGGMGGGGGGGFGGGGADFGDIFGDVFGDIFGGGRRQRASRGSDLRYNMELSLEEAVRGVTKEIRIPALEECDVCHGNGAKPGSSPITCPTCHGNGQVQMRQGFFTVQQACPHCHGRGKIIKDPCIKCHGHGRVEKSKTLSVKIPAGVDTGDRIRLSGEGEAGDHGAPSGDLYVQVQVKAHPIFQREENNLYCEVPINFAMAALGGEIEVPTLDGRVKLKVPAETQTGKLFRMRGKGVKSVRGGAQGDLLCRVVVETPVNLNERQRQLLQELDESFGGPSGERNSPRSKNFFDGVKKFFDDLTR
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRPR_PSEPU
Sequence: MARKTAAEAEETRQRIIDAALEVFVAQGVSDATLDQIARKAGVTRGAVYWHFNGKLEVLQAVLASRQHPLELDFTPDLGIERSWEAVVVAMLDAVHSPQSKQFSEILIYQGLDESGLIHNRMVQASDRFLQYIHQVLRHAVTQGELPINLDLQTSIGVFKGLITGLLYEGLRSKDQQAQIIKVALGSFWALLREPPRFLLCEEAQIKQVKSFE
What is the function of this protein?
In conjunction with SrpS represses the srpABC operon.
What are the official names of this protein?
HTH-type transcriptional regulator SrpR, Solvent efflux pump srpABC operon corepressor.
Protein: Y1316_METTH
Sequence: MNYFSMENHNFRQIKSEIRILGIDDAPFTPRSEEDVLLVGTVFRGGQWLDGVLTTTVRVDGDDATERIIEMVNGSRHLNQLRVIMLDGLTFGGFNVVDIVELSERTGLPVIVVVRKHPDMERIKRALKHRFSDWKARWRSIERAGRIHRVESREPLYIQTAGIEPDDAAEIVRISTTRSSIPEPLRAAHIIASGVTLGESRGSA
What are the official names of this protein?
UPF0215 protein MTH_1316.
What is the protein family that this protein belongs to?
Belongs to the UPF0215 family.
Protein: TRPA_JANSC
Sequence: MTRIDDTFARLSASGKKAFVSYIMAGDPDYATSLEVMRGLPAAGVDIIELGLPFTDPMADGSTIQLAGQRALDGGMTLDKTLQMVRDFRAGDDTTPIVLMGYYNPIYSRGVDRFLTDAREAGIDGLIVVDLPPEEDEELCIPAQAAGLNFIRLATPTTDDARLPAVLSNTSGFLYYVSITGITGAAAPQAADVAPEVARIKSATDIPVIVGFGITTSEAARTIAGVADGCVVGSAIVSRIAEGEPVADVLAFVKSLSDGAHAA
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: Y1124_NEIMB
Sequence: MKPLILGLAAVLALSACQVQKAPDFDYTSFKESKPASILVVPPLNESPDVNGTWGVLASTAAPLSEAGYYVFPAAVVEETFKQNGLTNAADIHAVRPEKLHQIFGNDAVLYITVTEYGTSYQILDSVTTVSAKARLVDSRNGKELWSGSASIREGSNNSNSGLLGALVSAVVNQIANSLTDRGYQVSKTAAYNLLSPYSHNGILKGPRFVEEQPK
What are the official names of this protein?
Putative lipoprotein NMB1124/NMB1162.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: MENA_ECOLI
Sequence: MTEQQISRTQAWLESLRPKTLPLAFAAIIVGTALAWWQGHFDPLVALLALITAGLLQILSNLANDYGDAVKGSDKPDRIGPLRGMQKGVITQQEMKRALIITVVLICLSGLALVAVACHTLADFVGFLILGGLSIIAAITYTVGNRPYGYIGLGDISVLVFFGWLSVMGSWYLQAHTLIPALILPATACGLLATAVLNINNLRDINSDRENGKNTLVVRLGEVNARRYHACLLMGSLVCLALFNLFSLHSLWGWLFLLAAPLLVKQARYVMREMDPVAMRPMLERTVKGALLTNLLFVLGIFLSQWAA
What is the function of this protein?
Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).  Attaches octaprenylpyrophosphate, a membrane-bound 40-carbon side chain to DHNA.  The conversion of DHNA to DMK proceeds in three stages: the removal of the carboxyl group of DHNA as CO(2), the attachment of the isoprenoid side chain, and a quinol-to-quinone oxidation, which is thought to be spontaneous.
What are the official names of this protein?
1,4-dihydroxy-2-naphthoate octaprenyltransferase, DHNA-octaprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MenA family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CSRA_ECOL5
Sequence: MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHREEIYQRIQAEKSQQSSY
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
Protein: RISB_BACC7
Sequence: MVFEGHLVGTELKVGVVVGRFNEFITSKLLGGALDGLKRHGVEEADIDVAWVPGAFEIPLIAKKMANSGKYDAVITLGTVIRGATTHYDYVCNEVAKGVASLSLQTDIPVIFGVLTTETIEQAIERAGTKAGNKGYESAVAAIEMAHLSKQWA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: TX90B_PHONI
Sequence: MKCAVLFLSVIALVHIFVVEAEEEPDSDALVPQERACIPRGEICTDDCECCGCDNQCYCPPGSSLGIFKCSCAHANKYFCNRKKEKCKKA
What is the function of this protein?
Potent blocker of nociceptor cation channels TRPA1 and high voltage-activated calcium channels (PubMed:12470700, PubMed:15933156, PubMed:27759880).  It acts mainly on P/Q-type (Cav2. 1/CACNA1A) calcium channels and has a minor effect on L- (Cav1/CACNA1) and N-type (Cav2. 2/CACNA1B) calcium channels (PubMed:12470700, PubMed:15933156).  Blocks glutamate release in synaptic transmission mediated by calcium channels (PubMed:12470700).  The toxin also inhibits the KCl-induced increase of intrasynaptosomal free calcium (PubMed:12470700).  It also shows antiproliferative effects on different glioma cell lines (M059J, U-138MG and U-251MG) (PubMed:28202361).  In vivo, it shows analgesic effects in rodent models of pain (PubMed:18774645).  In addition, it selectively blocks nocifensive responses evoked by reactive TRPA1 channel agonist (PubMed:27759880).  Furthermore, it also reduces the TRPA1 channel-dependent hyperalgesia in a model of neuropathic pain induced by the chemotherapeutic agent BTZ (PubMed:27759880).  In addition, it causes reduction of tumor area in the mouse glioma model, that is induced by the orthotopic injection of GL261 cells into the brain (PubMed:28202361).
What are the official names of this protein?
Omega-ctenitoxin-Pn4a, Omega-CNTX-Pn4a, CTK 01512-2, Neurotoxin Tx3-6, PnTx3-6, Ph-alpha-1-beta toxin.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 09 (Tx3-6) family.
What are the subcellular locations of this protein?
Secreted.
Protein: EIF3A_SCHPO
Sequence: MAPPQGKPENVLRLADELIALDQHSSALQSLHETIVLKRSRNAQGFSLEPIMMRFIELCVHLRKGKIAKEGLYTYKNAVQNTSVTAIENVVKHFIELANKRVQEAQEKADKISVEYVDDLEATETPESIMMSLVSGDLSKSRTDRALVTPWLKFLWDAYRTVLDILRNNARLEVMYQLIANSAFQFCLKYQRKTEFRRLCELLRSHLGNASKFSNAPHSINLNDAETMQRHLDMRFSQLNVAVELELWQEAFRSIEDIHSLLTFSKRAPAAVMLGNYYRKLIKIFLVCDNYLLHAAAWNRYFTFTNVQKPATANFVILSALSIPIIDANKLSGPSIEAEDAKSKNARLALLLNLSKTPTRETLIKDAISRGVLSFCDQAIRDLYQILEVEFHPLSICKKLQPIIKRLAESNDTAQYIRPLQQVILTRLFQQLSQVYDSISLKYVMDLATFEEPYDFNPGQIEKFIMNGNKKGAFSIRLNHIENSISFSSDLFSNPIKSSDSVSLQSTPSELITSQLTRIAKSLSSVLMRFDTDFCLLRKQQAEAAYERAQAGVEQERKAVIAQRSLLELRRGQADTLATQREAELAAQRALKQKQESEAESLRVQEEINKRNAERIRREKEAIRINEAKKLAEELKAKGGLEVNAEDLEHLDADKLRAMQIEQVEKQNKSMNERLRVIGKRIDHLERAYRREAIPLWEEDAKQQAEHDREIFYEREKQRKEVQERKHEQAIKDKKAFAQFASYIHAYKQNIDDERDKAYQEAYAKAKNVIDAERERQRKEIFEQKLAEAIREAEEEAARAAEEEANRELHEQEEAQKRAIEERTRAAREAKEREQREMAEKLERQRRIQQERDEEISRKLAEKAAARRANIGASSPSPGAWRRGGASAGGVSRDSPRYSRGGYSRGSVPPRETLAPSKGAYVPPSRRNQQQQ
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit A, eIF3a, Eukaryotic translation initiation factor 3 110 kDa subunit, eIF3 p110, Translation initiation factor eIF3, p110 subunit.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit A family.
What are the subcellular locations of this protein?
Cytoplasm.