PharMolix/UniProtQA huggingface dataset:
Protein: RIFK_NEUCR
Sequence: MSLPNPDNRPLLIGPPTGPEAPFPFRMEGEVISGFGRGSKELGIPTANLPVDDENAWIKNIDSGIYFGWASLKLPASHPNSVLYQKPPTSEPVMMDPVQQQQQQQQQQRNQQQQQEGGVGSAQQEKLVDQETGQWQIYPMVMSIGYNPFYKNTVRSAEVHVLGEFAADFYGVGMRLLITGFIRNEKDYSGLEALIADIHFDCEVARHSLARKGWRVRELGVKEGEEEGELDGSWLVR
What is the function of this protein?
Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme.
What are the official names of this protein?
Riboflavin kinase, Flavin mononucleotide kinase 1.
What is the protein family that this protein belongs to?
Belongs to the flavokinase family.
Protein: NPL4_MOUSE
Sequence: MAESIIIRVQSPDGVKRITATKRETAATFLKKVAKEFGFQNNGFSVYINRNKTGEITASSSKSLHLLKIKHGDLLFLFPSSLAGPSSEMETSTSVGLKAFGAPNVVEDEIDQYLSKQDGKIYRSRDPQLCRHGPLGKCVHCVPLEPFDEDYLNHLEPPVKHMSFHAYIRKLTGGADKGKFVALENISCKIKSGCEGHLPWPNGICTKCQPSAITLNRQKYRHVDNIMFENHTVADRFLDFWRKTGNQHFGYLYGRYTEHKDIPLGIRAEVAAIYEPPQIGTQNSLELLEDPKAEVVDEIAAKLGLRKVGWIFTDLVSEDTRKGTVRYSRNKDTYFLSSEECITAGDFQNKHPNICRLSPDGHFGSKFVTAVATGGPDNQVHFEGYQVSNQCMALVRDECLLPCKDAPELGYAKESSSEQYVPDVFYKDIDKFGNEITQLARPLPVEYLIIDITTTFPKDPVYTFSISQNPFPIENRDVLGETQDFHSLATYLSQNTSSVFLDTISDFHLLLFLVTNEVMPLQDSISLLLEAVRTRNEELAQTWKKSEQWATIEQLCSTVGVQLPGLHEFGAVGGSARAATSAMWACQHCTFMNQPGTGHCEMCSLPRT
What is the function of this protein?
The ternary complex containing UFD1, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome.  The NPLOC4-UFD1-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope (By similarity).  Acts as a negative regulator of type I interferon production via the complex formed with VCP and UFD1, which binds to RIGI and recruits RNF125 to promote ubiquitination and degradation of RIGI (By similarity).
What are the official names of this protein?
Nuclear protein localization protein 4 homolog, Protein NPL4.
What is the protein family that this protein belongs to?
Belongs to the NPL4 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Endoplasmic reticulum. Nucleus. Note=Associated with the endoplasmic reticulum and nuclear.
Protein: Y827_METJA
Sequence: MKVNDMFWFWLILGIIALFIIVKAIVIVNQYEGGLIFRLGRVIGKLKPGINIIIPFLDVPVKVDMRTRVTDIPPQEMITKDNAVVKVDAVVYYRVIDVEKAILEVEDYEYAIINLAQTTLRAIIGSMELDEVLNKREYINSKLLEILDRETDAWGVRIEKVEVKEIDPPEDIKNAMAQQMKAERLKRAAILEAEGEKPE
What are the official names of this protein?
Uncharacterized protein MJ0827.
What is the protein family that this protein belongs to?
Belongs to the band 7/mec-2 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: VATA_AEDAE
Sequence: MSTLKKISDEDRESKFGYVFAVSGPVVTAERMSGSAMYELVRVGYYELVGEIIRLEGDMATIQVYEETSGVTVGDPVLRTGKPLSVELGPGIMGSIFDGIQRPLKDINELTSSIYIPKGVNIPCLSRTQSWGFNPLNVKVGSHITGGDLYGLVHENTLVKHKLLVPPRAKGTVRYIAPPGNYTVDDIILETEFDGEINKWSMLQVWPVRQPRPVTEKLPANHPLLTGQRVLDSLFPCVQGGTTAIPGAFGCGKTVISQALSKYSNSDVIIYVGCGERGNEMSEVLRDFPELSVEIDGVTESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYNVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSINWLISYSKYMRALDDFYDKNFQEFVPLRTKVKEILQEEEDLSEIVQLVGKASLAETDKITLEVAKLLKDDFLQQNSYSAYDRFCPFYKTVGMLRNMIGFYDMARHAVETTAQSENKITWNVIRDSMGNILYQLSSMKFKDPVKDGEAKIKADFDQLYEDLQQAFRNLED
What is the function of this protein?
Catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).
What are the official names of this protein?
V-type proton ATPase catalytic subunit A, V-ATPase subunit A, V-ATPase 69 kDa subunit, Vacuolar proton pump subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: TYSY_MOUSE
Sequence: MLVVGSELQSDAQQLSAEAPRHGELQYLRQVEHILRCGFKKEDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVRIWDANGSRDFLDSLGFSARQEGDLGPVYGFQWRHFGAEYKDMDSDYSGQGVDQLQKVIDTIKTNPDDRRIIMCAWNPKDLPLMALPPCHALCQFYVVNGELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLQPGDFVHTLGDAHIYLNHIEPLKIQLQREPRPFPKLKILRKVETIDDFKVEDFQIEGYNPHPTIKMEMAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine 5'-monophosphate (dUMP) to thymidine 5'-monophosphate (dTMP), using the cosubstrate, 5,10- methylenetetrahydrofolate (CH2H4folate) as a 1-carbon donor and reductant and contributes to the de novo mitochondrial thymidylate biosynthesis pathway.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Mitochondrion. Mitochondrion matrix. Mitochondrion inner membrane.
Protein: MINE_ECOSE
Sequence: MALLDFFLSRKKNTANIAKERLQIIVAERRRSDAEPHYLPQLRKDILEVICKYVQIDPEMVTVQLEQKDGDISILELNVTLPEAEELK
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: RL36_XENLA
Sequence: MAIRYPMAVGLNKGHRVTKNVTKPRHCRRRGRLTKHTKFVRDMIREVCGFAPYERRAMELLKVSKDKRALKFIKKRIGTHIRAKRKREELSNVLAAMRKAAAKKD
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL36 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Note=Detected on cytosolic polysomes.
Protein: DFP11_HYPCU
Sequence: MWATYVFIAVSLACANGYSSGAPESVCQDMVPKHPVPPQSTPPPYTITTSTKTVKAGTPMEVVITGKKPTDKMRGLLLQAREGTKIVGKFTLAPNDPFAQLLNCGEPGNAITHKKHDEKNDKQTVAFTWTPPKDFVGEIKFRATIALNGAVFWVGVESGPVKVIS
What is the function of this protein?
As this protein is expressed upon bacterial infection, it may have antimicrobial activity.
What are the official names of this protein?
Putative defense protein Hdd11, Hyphantria differentially displayed gene 11.
What is the protein family that this protein belongs to?
Belongs to the insect defense protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: TOP6A_METMA
Sequence: MEGEKGSKTRKGDALAREKLLEIAEKIYNQFEEEVVPSVSLPSRTKANLEYSDESDVWVYGDRESERSAKTVKGAFQLLKTTYATDFLINEHLARNRGSTLRELYYISEGWDYAKFKEQGESDRLIEDLEILTSLQREYFHMRPEEDGATMFGPIEITEQTKRGERNIHCQKDVGEGGYQIPFNVENIEFQKHDASMIIAIETGGMYARLMENGFDEAYNAILVHLKGQPARSTRRIIKRMNEELGIPVAVFTDGDPWSYRIYASVAYGAIKSAHLSEFMATPAAKFLGLQPSDIVEYELSTDKLTEQDVSALRSELSDPRFESDYWKEQIQLQLDIGKKAEQQAFAGKGLDFVTEVYLPNRLKEMGMI
What is the function of this protein?
Relaxes both positive and negative superturns and exhibits a strong decatenase activity.
What are the official names of this protein?
Type 2 DNA topoisomerase 6 subunit A, Type II DNA topoisomerase VI subunit A.
What is the protein family that this protein belongs to?
Belongs to the TOP6A family.
Protein: ENL01_ARATH
Sequence: MSAIMKSLCFSFLILASFATFFSVADAWRFNVGGNGAWVTNPQENYNTWAERNRFQVNDSLYFKYAKGSDSVQQVMKADFDGCNVRNPIKNFENGESVVTLDRSGAFYFISGNQDHCQKGQKLIVVVLAVRNQPSAPAHSPVPSVSPTQPPKSHSPVSPVAPASAPSKSQPPRSSVSPAQPPKSSSPISHTPALSPSHATSHSPATPSPSPKSPSPVSHSPSHSPAHTPSHSPAHTPSHSPAHAPSHSPAHAPSHSPAHAPSHSPAHSPSHSPATPKSPSPSSSPAQSPATPSPMTPQSPSPVSSPSPDQSAAPSDQSTPLAPSPSETTPTADNITAPAPSPRTNSASGLAVTSVMSTLFSATFTFLMFA
What is the function of this protein?
May act as a carbohydrate transporter.
What are the official names of this protein?
Early nodulin-like protein 1, AtENODL1, Phytocyanin-like protein ENODL1.
What is the protein family that this protein belongs to?
Belongs to the early nodulin-like (ENODL) family.
Protein: MCH2_YEAST
Sequence: MSEERHEDHHRDVENKLNLNGKDDINGNTSISIEVPDGGYGWFILLAFILYNFSTWGANSGYAIYLAHYLENNTFAGGSKLDYASIGGLAFSCGLFFAPVITWLYHIFSIQFIIGLGILFQGAALLLAAFSVTLWEIYLTQGVLIGFGLAFIFIPSVTLIPLWFRNKRSLASGIGTAGSGLGGIVFNLGMQSILQKRGVKWALIAQCIICTSLSTIALMLTRTTHQGLRQHKRSYKFELLDYDVLSNFAVWLLFGFVSFAMLGYVVLLYSLSDFTVSLGYTSKQGSYVSCMVSVGSLLGRPIVGHIADKYGSLTVGMILHLVMAILCWAMWIPCKNLATAIAFGLLVGSIMGTIWPTIASIVTRIVGLQKLPGTFGSTWIFMAAFALVAPIIGLELRSTDTNGNDYYRTAIFVGFAYFGVSLCQWLLRGFIIARDEIAVREAYSADQNELHLNVKLSHMSKCLFRYKQLPRRV
What is the function of this protein?
Probable transporter.  Does not act in the transport of monocarboxylic acids across the plasma membrane.
What are the official names of this protein?
Probable transporter MCH2.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CAP8_ADE41
Sequence: MSKEIPTPYMWSYQPQMGLAAGASQDYSSRMNWLSAGPHMIGRVNGIRATRNQILLEQAALTSTPRSQLNPPNWPAAQVYQENPAPTTVLLPRDAEAEVQMTNSGAQLAGGSRHVRFRGRSSPYSPGPIKRLIIRGRGIQLNDEVVSSLTGLRPDGVFQLGGAGRSSFTPRQAYLTLQSSSSQPRSGGIGTLQFVEEFVPSVYFNPFSGAPGLYPDDFIPNYDAVSESVDGYD
What is the function of this protein?
Structural component of the virion that acts as a cement protein on the capsid interior and which glue the peripentonal hexons and group-of-nine hexons together.
What are the official names of this protein?
Pre-hexon-linking protein VIII, Pre-protein VIII, pVIII.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae hexon-linking protein family.
What are the subcellular locations of this protein?
[Hexon-linking protein-C]: Virion. Note=Located on the inner side of the capsid shell. Present in 120 copies per virion. SUBCELLULAR LOCATION: [Pre-hexon-linking protein VIII]: Host nucleus. SUBCELLULAR LOCATION: [Hexon-linking protein-N]: Virion. Note=Located on the inner side of the capsid shell. Present in 120 copies per virion.
Protein: PORTL_BPAPS
Sequence: MAETLQKRHEQIMRKFDRAHSPQEAVREKCLEATRFARVPGGQWEGATAAGSELGKHFEKYPKFEINKISTELNRIISEYRHNRITVKFRPGDKTASEALANKLNGLFRADYEETDGGEACDNAFDDGSTGGFGCFRLTTNLVNALDPMDERQRICLEPIYDPARSVWFDPDAKKYDKSDAEWAFCMYSLSAEKYKAEYNKDPATLMSGIERSWDYDWYDVDVVYIAKYYEVKKESVDVVSFQNPLTSETVTYDSDQLELVEDELADIGFIEAARRTIKRRRVYVSVVDGEGFLEKAQRIPGEHIPLIPVYGKRWFIDDIERVEGHIAKAMDAQRLYNLQVSMLADSATQDTGSIPIVGKSQIKTLEKYWANRNKNRPAFLPLNEIVDKQGNIIAPPTPVGYTQPQPLNQAMAALLQQTGADIQEVTGSSQAMQPMPSNIAKETVNHLMHRSDMSSFIYLDNMAKSLKRAGEVWLSMAREVYGSDRQVRIVNADGTDDIALMSVVINDNQTGQVVAMNDLSSGRYDVTVDVGPSYTARRDATVSVLTNLLAGMLPQDPMRQVLQGIILDNMEGEGLDEFKEYNRKQLLTQGVVKPRNTEEEQMVAQMIQQAQQPNAELVAAQGVLMQGQAEVQKAKNEELAIQVKAFQAQTEARVAEAKMVQILASADSAKRAEIREALKMLHQFQKEQGDASRADAELILKATDTQHKQNRDAAKNHSI
What is the function of this protein?
Forms the portal vertex of the capsid.  This portal plays critical roles in head assembly, genome packaging, neck/tail attachment, and genome ejection.  Procapsid assembly may initiate with a nucleation complex composed of portal and scaffolding proteins (By similarity).  The portal protein multimerizes as a single ring-shaped homododecamer arranged around a central channel.
What are the official names of this protein?
Portal protein, Gene product 19, Gp19, Head-to-tail connector.
What is the protein family that this protein belongs to?
Belongs to the p22likevirus portal protein family.
What are the subcellular locations of this protein?
Virion.
Protein: ATPH_PAUCH
Sequence: MSDLTSAASVLAAALAVGLAAIGPGIGQGTAAGSAVEGIARQPEAEGKIRGTLLLSLAFMEALTIYGLVVALVLLFANPFVK
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit C, organellar chromatophore, ATP synthase F0 sector subunit C, ATPase subunit III, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Plastid, organellar chromatophore thylakoid membrane; Multi-pass membrane protein.
Protein: RMLB_HAEIN
Sequence: MMNILVTGGSGFIGSALIRYIINHTQDFVINIDKLTYAANQSALREVENNPRYVFEKVDICDLNVIENIFEKYQPDAVMHLAAESHVDRSISGAADFVQTNIVGTYTLLEVAKNYWHTLDEAKKTTFRFHHISTDEVYGDLSLSEPAFTEQSPYHPSSPYSASKAASNHLVQAWHRTYGLPVIITNSSNNYGAYQHAEKLIPLMISNAVMGKPLPIYGDGQQIRDWLFVEDHVQASYLVLTKGRVGENYNIGGNCEKTNLEVVKRICQLLEELAPSKPNHIKYYEDLMTFVKDRPGHDVRYSLDCSKIHAELGWQPQITFEQGLRQTVKWYLFNSSSS
What is the function of this protein?
Catalyzes the dehydration of dTDP-D-glucose to form dTDP-6-deoxy-D-xylo-4-hexulose via a three-step process involving oxidation, dehydration and reduction.
What are the official names of this protein?
dTDP-glucose 4,6-dehydratase.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
Protein: KV15_RABIT
Sequence: IVMTQTPSSKSVPVGDTVTINCQASQSVYSNNRLAWFQQKPGQPPKLLIYKASTLASGVPSRFKGSGSGTQFTLTISDVQCADAATYYCRVASTNNIVFGGGTEVVVKGD
What are the official names of this protein?
Ig kappa chain V region K29-213.
Protein: IPKA_MOUSE
Sequence: MTDVETTYADFIASGRTGRRNAIHDILVSSASGNSNELALKLAGLDINKTEGEDDGQRSSTEQSGEAQGEAAKSES
What is the function of this protein?
Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.
What are the official names of this protein?
cAMP-dependent protein kinase inhibitor alpha, PKI-alpha, cAMP-dependent protein kinase inhibitor, muscle/brain isoform.
What is the protein family that this protein belongs to?
Belongs to the PKI family.
Protein: RL15_CHLT2
Sequence: MIKLECLQDPSPRKRRTKLLGRGPSSGHGKTSGRGHKGDGSRSGYKRRFGYEGGGVPLYRRVPTRGFSHKRFDKCVEEITTQRLNEIFDNGAEVSLEALKERKVIHRETSRVKVILKGALDKKLVWKDAAIVLSEGVKSLIEAV
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: LON_BRUA2
Sequence: MTGIEQKTPVGGSETGGADGLYAVLPLRDIVVFPHMIVPLFVGREKSIRALEEVMGVDKQILLATQKNAADDDPAPDAIYEIGTIANVLQLLKLPDGTVKVLVEGTARAKISKFTDREDYHEAYAAALQEPEEDAVEIEALARSVVPDFENYVKLNKKISPEVVGAASQIDDYSKLADTVASHLAIKIPEKQEMLSVLSVRERLEKALSFMEAEISVLQVEKRIRSRVKRQMEKTQREYYLNEQMKAIQKELGDSEDGRDEVAEIEERITKTKLSKEAREKALAELKKLRSMSPMSAEATVVRNYLDWLLSIPWGKKSKVKQDLNFAQEVLDAEHFGLGKVKERIVEYLAVQARSTKIKGPILCLVGPPGVGKTSLARSIAKATGREYVRMSLGGVRDEAEIRGHRRTYIGSMPGKVIQSMKKAKKSNPLFLLDEIDKMGQDFRGDPSSAMLEVLDPEQNATFMDHYLEVEYDLSNVMFVTTANTMNIPVPLLDRMEIIRIAGYTEDEKLEIAKRHLLPKAIKDHALQPKEFSVTEDALRNVIRHYTREAGVRSLEREVMTLARKAVTEILKTKKKSVKITDKNLSDYLGVEKFRFGQIDGEDQVGVVTGLAWTEVGGELLTIEGVMMPGKGRMTVTGNLRDVMKESISAAASYVRSRAIDFGIEPPLFDKRDIHVHVPEGATPKDGPSAGIAMVTAIVSVLTGIPVRKDIAMTGEVTLRGRVLPIGGLKEKLLATLRGGIKKVLIPEENAKDLAEIPDNVKNNLEIVPVSRVGEVLKHALVRQPEPIEWTEQENPTAVPPVEDEAGASLAH
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner (By similarity).  Required for wild-type virulence during the initial stages of infection in the mouse model, but not essential for the establishment and maintenance of chronic infection in this host.
What are the official names of this protein?
Lon protease, ATP-dependent protease La.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLK_SALEP
Sequence: MTKYALVGDVGGTNARLALCDIASGEISQAKTYSGLDYPSLEAVVRVYLDEHSVSVEDGCIAIACPITGDWVAMTNHTWAFSIAEMKKNLGFSHLEIINDFTAVSMAIPMLKKEHLIQFGGGEPVDGKPIAVYGAGTGLGVAHLVHVDKRWISLPGEGGHVDFAPNSEEEAMILEILRAEIGHVSAERVLSGPGLVNLYRAIVKSDNRLPENLRPKDITERALADSCIDCRRALSLFCVIMGRFGGDLALTMGTFGGVYIAGGIVPRFLEFFKASGFRGGFEDKGRFKDYVHGIPVYLIVHDNPGLLGSGAHLRQTLGHIL
What are the official names of this protein?
Glucokinase, Glucose kinase.
What is the protein family that this protein belongs to?
Belongs to the bacterial glucokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_RALSO
Sequence: MTKFVFVTGGVVSSLGKGIAAASLAAILESRGLKVTLLKLDPYINVDPGTMSPFQHGEVFVTEDGAETDLDLGHYERFVSAKMRKANNFTTGQIYESVIRKERRGEYLGKTVQVIPHITNEIQAFIERGAKASHDGKADVAIVEIGGTVGDIESLPFLEAARQMSLRLGRNQAAFVHLTLVPFIASAGELKTKPTQHSVQKLREIGVQPTALLCRADRPIPDDERAKISLFANMPQDAVISVWDVDTIYKIPQMLNEQGLDRIICEELRIDAPPADLSMWSRMVHTLENPQHEITIGMVGKYVDLTESYKSLIEALRHAGLHTSTRVNIEYIDSEELESGHTQVLESLDAILVPGGFGKRGTEGKIRAIQYAREKTVPYLGICLGMQLAVIEFARHVAGMQDANSTEFNLETEHPVVALITEWQDRDGRVEKRSADSDLGGTMRLGAQRVPVQTGTKASQIYGAEVNERHRHRYEVNNHYVPQLEKSGMIISARTPSENLPEMMELPGAMHPWFVGVQFHPEFTSTPRDGHPLFKAYVEAALAHRQRQAQRAVA
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: NTCP7_MOUSE
Sequence: MRLLERARKEWFMVGIVVAIGAAKLEPSVGVNGGPLKPEITVSYIAVATIFFNSGLSLKTEELTSALVHLRLHLFIQIFTLAFFPAAIWLFLQLLSVTSINEWLLKGLQTVGCMPPPVSSAVILTKAVGGNEAAAIFNSAFGSFLGIVVTPVLLLLFLGSSSSVPFTSIFSQLFMTVVVPLVIGQIVRRYIKDWLERKKPPFGVVSSSVLLMIIYTTFCDTFSNPNIDLDKFSLILILFIIVSVQLSFMLLTFIFSTRNNSGFTPADTVAIIFCSTHKSLTLGIPMLKIVFAGHEHLSLISVPLLIYHPAQILLGSVLVPTIKSWMVSRQKGVKLTRPTV
What is the function of this protein?
Involved in teeth and skeletal development.  Has an essential role in the biosynthesis and trafficking of glycosaminoglycans and glycoproteins to produce a proper functioning extracellular matrix.  Required for extracellular matrix mineralization (PubMed:30082715).  Also involved in the regulation of cellular calcium homeostasis (By similarity).  Does not show transport activity towards bile acids or steroid sulfates (including taurocholate, cholate, chenodeoxycholate, estrone-3-sulfate, dehydroepiandrosterone sulfate (DHEAS) and pregnenolone sulfate).
What are the official names of this protein?
Sodium/bile acid cotransporter 7, Na(+)/bile acid cotransporter 7, Solute carrier family 10 member 7.
What is the protein family that this protein belongs to?
Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane.
Protein: CLPS_SHESM
Sequence: MGKTGNIEHVEERVESELMPPSMYKVILNNDDYTPMDFVIEVLQIFFRKNEQEATDIMLTIHHQGKGICGIFPYGIAETKVIQVNQFARQNQHPLLCSLEKA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: ISCS_SHEB5
Sequence: MKLPIYLDYAATTPVDPRVAEKMFQCMTMDGIFGNPASRSHRYGWQAEEAVDIARNQIAELINADHREIVFTSGATESNNLAIKGVAHFYHKKGKHIITSKTEHKAVLDTCRQLEREGFEVTYLEPAANGIIPMERLETAMRDDTILVSIMHVNNEIGVIHDIDAIGELCRSKGIIFHMDAAQSAGKVPIDVQATKVDLISISGHKMYGPKGIGALYVRRKPRIRLEAQMHGGGHERGMRSGTLPTHQIVGLGEAAAIAKAEMASDDARIGALRDKLWNGIKHIEETYINGDAIERVSGSLNVSFNYVEGESLMMALKDLAVSSGSACTSASLEPSYVLRALGLNDEMAHSSIRFSIGRFTTEEEIDHAIEVITQSIDKLREMSPLWEMFKDGIDLNQVQWAHH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAIC_SALPK
Sequence: MDIVGGQNLRQMWDDLAEVYGDKTALIFESCEGIVRQFSYASLNEEINRTANLFHSLGIRKGDRVALHLDNCPEFIFCWFGLAKIGAIMVPINARLLGEESAWILQNSQVSLLVTSAQFYPMYREIRQGNSTPLNHICLIGEQLPADDGVSLFSQLQARQSATLCYTPALSTDDAAEILFTSGTTSRPKGVVITHYNLRFAGYYSAWQIALRDDDVYMTVMPAFHIDCQCTAAMPAFSAGSTFVLLEKYSARAFWGQVRKYQATVTECIPMMIRTLMVQPAAPTDRQHHLREVMFYLNLSAQEKDAFTERFGVRLLTSYGMTETIVGIIGDRPGDKRRWPSIGRVGFSYEAEIRDDQNRPLPAGEIGEICIKGIPGKTIFKEYYMQPEATARALEPEGWLHTGDSGYQDEDGYFYFVDRRCNMIKRGGENVSCVELENIISAHPKIQDIVVVGIKDAIRDEAIKAFIVLNEGETLSEAEFFSFCENNMAKFKVPSFMEIRTDLPRNCSGKIIKKNLK
What is the function of this protein?
Catalyzes the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the CaiB reaction cycle.  Also has activity toward crotonobetaine and gamma-butyrobetaine.
What are the official names of this protein?
Crotonobetaine/carnitine--CoA ligase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: ARGR_CHLL2
Sequence: MNKQVRQSKIREMLHLHEVGNQHDLIRLLEEAGIRVAQATLSRDCSELGIIRSKGLNGYRLALPEENPGNIIKGLVEVEVLSIQSNEAVIIIKTLPGRAHGVGSFLDQLKNSQILGTIAGDDTVLVIPVSVAQISQVISYIQENLSKN
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATA_BRUC2
Sequence: MSELTALTIAEARDKLKAKAITATELTDAYLSAIDAANDAINAYVAVTHDQARSMAKASDERIAKGEAGALEGIPLGVKDLFATKGVHTQACSHILDGFKPEYESTVTANLWADGAVMLGKLNMDEFAMGSSNETSYYGPVKNPWRAKGSNADLVPGGSSGGSAAAVAAHLCAGATATDTGGSIRQPAAFTGTVGIKPTYGRVSRWGTVAFASSLDQAGPIARDVRDAAILMKSMASLDLKDTTSVDLPVPDYEAALGRSVKGMKIGIPREYRVDGMPGEIEELWQKGIQYLKDAGAEIVDISLPHTKYALPAYYIVAPAEASSNLARYDGVRYGLRVPGKDIADMYEQTRAAGFGKEVKRRIMIGTYVLSAGYYDAYYLRAQKVRTLIKKDFEDVFAKGVDAILTPATPSAAFGLADEVLANDPVKMYLNDIFTVTVNMAGLPGIAVPAGLNGQGLPLGLQLIGRPFEEETLFQAAHVIEQAAGRFTPAKWW
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.