PharMolix/UniProtQA huggingface dataset:
Protein: FEN1_CRYPI
Sequence: MGIKGLTKFLADNAPKSIQQQGIGSLLGKRVAIDASMWIYQFLAAIREGSQWGNLTNSSGESTSHINGMLSRTTRLLEAGIKPVFVFDGAPPEMKKDELTKRDERREKALAELEKAQEIGDEELIKKQSVRTIHVTKKQVEDVKKLLGFLGMPCIDAPSEAEAQCAELCKDGLVYGVVTEDADSLTFGTPIQIKQLNFSESSNKITDKSPSKQKNGMQIIKLSLILSELDINMDQFIDLCILSGCDYCGTIRGIGTSTAYKLLKKYHNIESILKNIDQTKNPIPGNFDFSKVRELFKNPLVSKNNQIKDLIKWSNPKYEELMEWLIKEQNFNEARVNSYCERIKKSKNKTSQTCLDGFFKTASNERKNTHETPSRPPLSEKQKSETRKEVDSSLSCDKKKVKIEETKIISEWGAPVSKNLSSQAEKDLAENSSEAPNQSSEIKVNKIEENKDSESSTVENTPSLQTKSPEPTMRPVKRKLNRLISESDED
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: UBIB_CELJU
Sequence: MIAFLRLLKILRVFARYRLDQLLPANLPLAATLLLLPFKLFPQPRLSRGERLRRACEDLGPIFVKFGQLLSTRPDLVPADIVLELNHLQDNVTPFSKGEFQRIVESSLGASVAEVFASFNIEPLASASVAQVHTAVLKDGREVVIKVIRPGIDKVIAQDIALLLRVARWVENNTLDGKRLHPVEIVEDYRTTIFDELDLQREAANGSQLRRNFLNSPLLYVPEVYWEYTRTNVLVMERIYGIPVTDLAALNAQQTDMKKLAERGVEIFFTQVFEHNFFHADMHPGNIFVAHEHPSAPQYIAVDMAIVGSLTRADQYYLARNLLAMFRRDYRQVAELHVESGWVPSHVRVEELEAAVRTVCEPIFEKPLKEISFAQVLLNLFRTARRFEMEVQPQLVLLQKTLLNIEGLGRQLYPDLDLWATAHPFLERWLKNRFHPKSLWRELKRYAPEWMEKFPQVPNLVFNGLQQLQNLGELAPRLEEATHAYKAQQQLARQRNRRRVITLLAFAGAIALAWPSLGEGIRHWANHFSFGDIPTASYLLAAIGLSAWLLKR
What is the function of this protein?
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
What are the official names of this protein?
Probable protein kinase UbiB, Ubiquinone biosynthesis protein UbiB.
What is the protein family that this protein belongs to?
Belongs to the ABC1 family. UbiB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GCSH_FLAAN
Sequence: MALRMWASSTANALRLSSATRPHFSPLSRCFSSVLDGLKYANSHEWVKHEGSVATIGITDHAQDHLGEVVFVDLPEAGGSVTKATGFGAVESVKATSDVNSPISGEIVEVNSKLSETPGLINSSPYEDGWMIKVKPSNPSELDSLMGAKEYTKFCEEEDAAH
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ATPB_BACP2
Sequence: MKTGRISQIMGPVVDVRFEDGHLPEIYNAIRVSHKAESESEVDIDLTLEVALHLGDDTVRTIAMASTDGVKRGMEAVDLGKPISVPVGNVTLGRVFNVLGDNIDLDEPLGVEAQRDPIHRQAPSFDQLSTEVEILETGIKVVDLLAPYIKGGKIGLFGGAGVGKTVLIQELINNIAQEHGGISVFAGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEPPGARMRVALTGLTMAEHFRDELGQDVLFFIDNIYRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTNVGSVTSIQAIYVPADDYTDPAPATTFAHLDATTNLERKLTEMGIYPAVDPLASTSRALAPEIVGEEHYAIAREVQQTLQRYKELQDIIAILGMDELSEDDKLVVHRARRVQFFLSQNFHVAEQFTGQKGSYVPLKETVKGFKEILSGKYDHLPEDAFRLVGRIEEVVEKAKEMGVEA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: THEM_MALCI
Sequence: ALVTQSNAPSWGLGRISNRQAGIRDYHYLSGTSM
What is the function of this protein?
This is an extracellular proteinase with a general specificity for apolar residues.
What are the official names of this protein?
Thermomycolin, Thermomycolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: K1671_CHICK
Sequence: MEYYYCPRLLKFLQYLWDQLKQCFTRQPPEAKDTDTLVQEPDSQYGTWSEQRRSGDSFVPESPSSENDAISTRKQPPNSQPSSLSSQTEPTSLADRCDFSKDQRSTSLDRSSTDIDSTDGTELPPPGDAYPDGKTTDFSFIDQTTILDSSALKNRVQLSKKRRHRAPLSHSLRRSRGLEYENRFSLTEESGSTWMFKDSTEEKKPMQQEDSDEEEKTQRSGRLSSVQAQRLPIFPGMDHSVLKAQLRKRHESESPGEPSSAQPFKSPKPQLGTPGSRILPSSVEKEERSEEKSPQWLKELKSKERQSHYENQV
What are the official names of this protein?
Uncharacterized protein KIAA1671 homolog.
Protein: Y1358_VIBCH
Sequence: MNTPMFTRTSSLERTLETNKVLKNTYFLLSMTLVTSAIAAMATMAIGISPIVALVMQLAAIGILFFVMPKAINSSSGLVWTFVFTGLMGGALGPMLNFYAAMPNGPIVIAQALGLTGMVFLGLSAYTITSKKDFSFMRNFLFAGLIIVIVAALINIFVGSTVAHLAISSVSALVFSGFILFDTSRIVRGEETNYISATISMYLNILNLFTSLLSILGIMNNND
What are the official names of this protein?
Uncharacterized membrane protein VC_1358.
What is the protein family that this protein belongs to?
Belongs to the BI1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ISCU_THEMA
Sequence: MVFKMMYSEAILDYANSKKFRGKLDDATVIEEGKNISCGDEITLYLKVEDGVVKDAKFEGMGCVISQASASLMLERIIGERVEEIFSLIEEAEKMSRGENFDEGKLKNVTLMSDIKNYPARVKCFILAWKTLKEALKKISRP
What is the function of this protein?
A scaffold on which IscS assembles Fe-S clusters.  Subsequently gives the nascent cluster to other proteins.  It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters (By similarity).
What are the official names of this protein?
Iron-sulfur cluster assembly scaffold protein IscU, Sulfur acceptor protein IscU.
What is the protein family that this protein belongs to?
Belongs to the NifU family.
Protein: ATPE_CORGB
Sequence: MAEITVELVSVERMLWAGQASIVTAQTTEGEIGVLPDHEPLLGQLVENGVVTIQPIDGEKLIAGVSGGFLSVSKEKVTILADFAVWANEVDTASAEADLNSDDELAKARAEAGLRAVRRSSEGL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TBX5_RAT
Sequence: MADADEGFGLARTPLEPDSKDRSCDSKPESALGAPSKSPSSPQAAFTQQGMEGIKVFLHERELWLKFHEVGTEMIITKAGRQMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSDDLELHRMSRMRSKEYPVVPRSTVRHKVANHSPFSSETRALSTSSNLGSQYQCENGVSGPSQDLLPPPNPYPLAQEHSQIYHCTKRKDEECSSTEHPYKKPYMETSPSEEDTFYRSGYPQQQGLSTSYRTESAQRQACMYASSAPPSEPVPSLEDISCNTWPSMPSYSSCTVTTVQPMDRLPYQHFSAHFTSGPLVPRLAGMANHGSPQLGEGMFQHQTSVTHQPVVRQCGPQTGLQSPGSLQPPEFLYTHGVPRTLSPHQYHSVHGVGMVPEWSENS
What is the function of this protein?
DNA-binding protein that regulates the transcription of several genes and is involved in heart development and limb pattern formation.  Binds to the core DNA motif of NPPA promoter.
What are the official names of this protein?
T-box transcription factor TBX5, T-box protein 5.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between the cytoplasm and the nucleus. Acetylation at Lys-338 promotes nuclear retention.
Protein: PSBN_VITVI
Sequence: METATLVAISISGLLVSFTGYALYTAFGQPSQQLRDPFEEHGD
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: GLYA_TROWT
Sequence: MNHGVYQNLFIDSLDSVDPQIAEVLDLELRRQRDFLEMIASENFVPRAILQAQGSVLTNKYAEGYPQNRYYGGCECVDLAEDLAISRVRDLFGSEFANVQPHSGSTANAAALMALTEVGSTIMGLELDHGGHLTHGMPLSFSGKHYKAVTYRLDPKTCLIDMDSVRDLALRHRPSVIIAGWSAYVRHLDFEAFRSIADEVGARLWVDMAHFAGLVAAGLYPSPIPWADVVTSTTHKTLAGPRGGFILAKKEFGKAINTAVFPGQQGGPLMHVIAAKAVAFKVAASEGFRERQRITIEAARTVAKRIGEDYRLRDRGIDILTGGTDVHMVLVDMRKSDMDGLTGQNLLHEVGVTVNRNSMPYDKRPPRITSGIRIGTPALVTRGLSLDEFDEVADIISNALLTIDLPKQKQRALRIARTHPVYEGLRQY
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB6_HELMO
Sequence: MNWLEERLPGIGKVAEDIAEHPVPSHTLNIFYCLGGLTLLAFLVQCVTGLFLALYYKPTPEAAFASVQMITNEVRFGATIRSLHHWAANLMILLVFLHMLRVYYTGSFKKPRELNWLAGCFLLVLSLGLAFTGYLLPYEQLSYWASVIGAETAGSLPVVGATMKIMMQGGIKVTAEMLSRFYVLHVMILPLVTIGFLVAHFIMIRVQGISDPM
What is the function of this protein?
Component of the cytochrome bc complex which donates electrons to the photosynthetic reaction center.
What are the official names of this protein?
Cytochrome b6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: STPG2_MOUSE
Sequence: MYDRAPRWLDCANRGSTEEHVGPGTYQVPFPKQQATGCYAPFLSLSSKTSACVVSSDAGQAVPGPAHYNVSQAQYNIRGGRSLQNREKRFKKLISDGPGPGSYNWPYLGTLCITTRQKTPRTPAVSRNIDIPSIPSSGKSHGYHLNDDDTIMRRTPPPSDNTIGPAYYNPQFDYPKASLKYKGVNFGNATGRQEFLKYSGPGPGQYDIIQKRKLHCENINIKREQEHNYYTYVPRLYEAIILQEEKKGVPGPGKYNIKSEFDMIKSMSALVNSPSFIFFSETERFEPIKSCTPAPGTYNEIRTAFKCPKKRFGLSLPFNQSAARFTEDSKAQKLPGPGFYDISTNIVKAQVKKPCLKKQPKTGFGSSVPRTLFTAQKKAFRGPGPSDYQVRGTHDELPNLNKSAAFLSRAEKTPPVRKMRLPAPGRYDVQKSYDMSQVKHKYMPPRTSVAKKRHSSFLSAAPRCLGKIADGPGPATYSPVLMKSGAIISFVKGPKRFQEFHGEFSPGPTTYELSPFLRHSLLKRTYNVTLPCSSSPNRENTGCPSQKATQKFQREKLQYFN
What are the official names of this protein?
Sperm-tail PG-rich repeat-containing protein 2.
Protein: BCL9L_MOUSE
Sequence: MRILANKTRLPHPRRREAPGSPPLSPRGHCPPAPAKPMHPENKLTNHGKTGNGGAQSQHQNVNQGPTCNLGSKGVGAGSHGAKANQISPSNSSLKNPQAGVSPFSSLKGKVKRERSVSVDSGEQREAGTPSLDSEAKEVAPRSKRRCVLERKQPYSGDEWCSGPDSEEDDKPIAAAHNCNVADPAMVTPQLGPGQTAQLPLSESSAPGPQHGPQPGLRPDVPGGGGGGVPGKPPSQFVYVFTTHLANTAAEAVLQGRAESILAYHQQNVPRAKLDQAPKVPPTPEPLPLNTPSAGTPQSQPPPLPPPPPAPGSAPPALPPEGPPEDTSQDLAPNSVGAASTGGGTGGTHPNTPTAATANNPLPPGGDPGSAPGSALLGEATPTGNGQRNLVGSEGLSKEQLEHRERSLQTLRDIERLLLRSGETEPFLKGPPGGAGEGGPPAQAPSAAQPPPSAPPGGLKKYEEPLQSMISQTQSLGGPPLEHEVPGHPQGGDMGQQMNMMMQRLGQDSLTPEQVAWRKLQEEYYEEKRRKEEQIGLHGGRPLQDMVGMGGMMGRGPPPPYHSKPGDQWPPGMGAQLRGPMDVQDPMQLRPGPPFPGPRFPGNQMQRVPGFGGMQSMPMEVPMNAMQRPVRPGMAWNEDLPPIGGPSNFAQNAVPYPGGQGEAERFMTPRVREELLRHQLLEKRSMGMQRPLGMAGSGMGQSMEMERMIQAHRQMDPAMFPGQMTGGDGLAGTPMGIEFGGGRGLLSPPMGQSGLREVDPPMGPGNLNMNMNVNMNMNMNLNVQMTPQQQMLMSQKMRGPGDMMGPQGLSPEEMARVRAQNSSGMMGGPQKMLMPSQFPNQGQQGFSGGQGPYQAMPQDMGNTPDMFSPDQSSVPMGTVGTARLSHMPLPPASNPPGSVHLASNRGLGRRPSDLTISINQMGSPGMGHLKSPTLSQVHSPLVTSPSANLKSPQTPSQMVPLPSANPPGPLKSPQVLSSSLGVRSPTGSPSRLKSPSMAVPSPGWVASPKTAMPSPGVSQNKQPPLSINSSSTLGNVEQGALPPSAPRNSSSAPPANPSSGLMNPSLPFTSSPDPTPSQNPLSLMMSQMSKYAMPSSTPLYHNAIKTIATSDDELLPDRPLLPPPPPPQGSGPGISNNQPNQMHMNPAAAQSPMGMNLPGQQPLSHEPPPTMLPSPTPLGSNIPLHPNAQGTGGSSQNSMMMAPGGPDSLNAPCGPVPSSSQMMSFPPRLQQPHGAMAPTGAGGPGLQQHYPSGMALPPEDLPTQPPGPIPPQQHLMGKGMTGRMGDAYPPGVLPGVASVLNDPELSEVIRPTPTGIPEFDLSRIIPSEKPSSTLQYFPKSENQPPKAQPPNLHLMNLQNMMAEQTPSRPPNLPGQQGVQRGLSMSMCHPGQMSLLGRTGVPPQQGMVPHGLHQGVMSPPQGLMTQQNFMLMKQRGVGGEVYTQPPHMLSPQGSLMGPPPQQNLMVSHPLRQRSVSLDSQMGYLPTPGSMANLPF
What is the function of this protein?
Transcriptional regulator that acts as an activator.  Promotes beta-catenin transcriptional activity.  Plays a role in tumorigenesis.  Enhances the neoplastic transforming activity of CTNNB1.
What are the official names of this protein?
B-cell CLL/lymphoma 9-like protein, B-cell lymphoma 9-like protein, BCL9-like protein, BCL9-related beta-catenin-binding protein, Protein BCL9-2.
What is the protein family that this protein belongs to?
Belongs to the BCL9 family.
What are the subcellular locations of this protein?
Nucleus. Note=localized also in punctate nuclear bodies as well in the cytoplasm. Colocalizes with CTNNB1.
Protein: CSCL2_HUMAN
Sequence: MLPFLLATLGTTALNNSNPKDYCYSARIRSTVLQGLPFGGVPTVLALDFMCFLALLFLFSILRKVAWDYGRLALVTDADRLRRQERDRVEQEYVASAMHGDSHDRYERLTSVSSSVDFDQRDNGFCSWLTAIFRIKDDEIRDKCGGDAVHYLSFQRHIIGLLVVVGVLSVGIVLPVNFSGDLLENNAYSFGRTTIANLKSGNNLLWLHTSFAFLYLLLTVYSMRRHTSKMRYKEDDLVKRTLFINGISKYAESEKIKKHFEEAYPNCTVLEARPCYNVARLMFLDAERKKAERGKLYFTNLQSKENVPTMINPKPCGHLCCCVVRGCEQVEAIEYYTKLEQKLKEDYKREKEKVNEKPLGMAFVTFHNETITAIILKDFNVCKCQGCTCRGEPRPSSCSESLHISNWTVSYAPDPQNIYWEHLSIRGFIWWLRCLVINVVLFILLFFLTTPAIIITTMDKFNVTKPVEYLNNPIITQFFPTLLLWCFSALLPTIVYYSAFFEAHWTRSGENRTTMHKCYTFLIFMVLLLPSLGLSSLDLFFRWLFDKKFLAEAAIRFECVFLPDNGAFFVNYVIASAFIGNAMDLLRIPGLLMYMIRLCLARSAAERRNVKRHQAYEFQFGAAYAWMMCVFTVVMTYSITCPIIVPFGLMYMLLKHLVDRYNLYYAYLPAKLDKKIHSGAVNQVVAAPILCLFWLLFFSTMRTGFLAPTSMFTFVVLVITIVICLCHVCFGHFKYLSAHNYKIEHTETDTVDPRSNGRPPTAAAVPKSAKYIAQVLQDSEVDGDGDGAPGSSGDEPPSSSSQDEELLMPPDALTDTDFQSCEDSLIENEIHQ
What is the function of this protein?
Acts as an osmosensitive calcium-permeable cation channel (By similarity).  Mechanosensitive ion channel that converts mechanical stimuli into a flow of ion (By similarity).
What are the official names of this protein?
CSC1-like protein 2, Transmembrane protein 63B.
What is the protein family that this protein belongs to?
Belongs to the CSC1 (TC 1.A.17) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AROB_GEOSW
Sequence: MEQIVIETKTKQYPLFLGEGIIESLPDILRQLSFSKGTKLLIITDKTLEQLYLSRLCALLANDYDVYTYVIPSGEEAKSFEQYYACQTAALQYGLDRKSLILAFGGGVVGDLAGFVAATYMRGIPYIQIPTTLLAHDSAVGGKVAINHPLGKNMIGAFYQPEAVVYDIAFLRSLPEKELRSGFAEVIKHALIRDRDFYQWLRQEIRELADLKGERLQYCIKKGIEVKASVVREDEKETGVRAHLNFGHTLGHALENELGYGAMTHGDAVALGMLFAIFVSERVYNISLDYDRFSSWFRTYGFPVSIPKQLNINRLLEKMKGDKKARAGTVRMVLLKDIGMAEIKPLDDETLLALLRKFQREEGENDPRNSRCHYC
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANMK_TRIV2
Sequence: MYSSQASALPSRVIGLISGTSVDGIDAALVEITGTELDLKVELLAGKTYPYPAELRERILAVCAGEAISMLELADMDDAIALAFAQAAQNIQIGYQPVNLIGSHGQTVYHRPPKEAGVGKKTLGYTLQLGRGEMIAYLTGITTVSNFRVADIAVGGHGAPLVPRVDAFLLSHPHESRCIQNLGGIGNLAYIPARTDGWLSQIRGWDTGPSNSLLDLAVERLTAGAKTYDEDGQWAASGTPCYPLVEKWLTHEYFHLSPPKSTGRELFGVAYLNQCFQDAEPYQLSPADMLATLTELTVASIVHSYRTFLPQMPQRVFLCGGGSRNLYLKQRLQLALETIPVLTTDEAGVSADFKEAIAFAVLAHWRQLGIPGNLPTATGAPQEVLLGEIHQG
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: HTM_MYCBP
Sequence: MSTVLTYIRAVDIYEHMTESLDLEFESAYRGESVAFGEGVRPPWSIGEPQPELAALIVQGKFRGDVLDVGCGEAAISLALAERGHTTVGLDLSPAAVELARHEAAKRGLANASFEVADASSFTGYDGRFDTIVDSTLFHSMPVESREGYLQSIVRAAAPGASYFVLVFDRAAIPEGPINAVTEDELRAAVSKYWIIDEIKPARLYARFPAGFAGMPALLDIREEPNGLQSIGGWLLSAHLG
What is the function of this protein?
Involved in cellular response to chemical stress and may contribute to resistance toward antimicrobial natural compounds as well as drugs.  Catalyzes the methylation and detoxification of the P. aeruginosa toxin 2-heptyl-1-hydroxy-4(1H)-quinolinone (HQNO) to 2-heptyl-1-methoxy-4(1H)-quinolinone (HMOQ).
What are the official names of this protein?
2-heptyl-1-hydroxyquinolin-4(1H)-one methyltransferase, HQNO methyltransferase, HQNO-MTase, Heterocyclic toxin methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSTT2_ARATH
Sequence: MKLKVYADRMSQPSRAVLIFCKVNEIQFDEILISLGKRQQLSPEFKEINPMGKVPAIVDGRLKLFESHAILIYLSSAYASVVDHWYPNDLSKRAKIHSVLDWHHTNLRPGASGYVLNSVLAPALGLPLNPKAAAEAENILTNSLSTLETFWLKGSAKFLLGGKQPSIADLSLVCELMQLQVLDDKDRLRLLSPHKKVEQWIESTRKATMPHSDEVHEVLFRAKDRFQKQREMATASKPGPQSKIIQFSSIGGTSDGPNLVQDTTDRKARRRKWSPPDDVILISAWLNTSKDRKVVVYDEQQAHTFWKRIGAHVSNSASLANLPKREWNHCRQRWRKINDYVCKFVGCYDQALNQRASGQSEDDVFQVAYQLYYNNYMSNFKLEHAWRELRHNKKWCSTYTSENSKGGGSSKRTKLNGGGVYSSSCNPESVPIALDGEEQVMDRPLGVKSSKQKEKKVATKTMLEEREADSRSRLENLWVLDEEEQVMDLPLGVKSSKQKERKVATKTMIEEREAANFRSRLGNLWLLKEKEEREADSRSRLENLWALKEKDIEEQKKLTRMEVLKSLLGRRTGETSEKEETLKNKLIDEML
What is the function of this protein?
May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.
What are the official names of this protein?
Glutathione S-transferase T2, AtGSTT2, GST class-theta member 2, Glutathione S-transferase 10B.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Theta family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: RLMH_JANMA
Sequence: MQLVIAAVGHKMPAWIESGFGEYAKRMPADCRVHLKEIKPVERSGSKTAETAMALERAKIEAALPKGARIIALDEHGKDLTSVQLAQLLTQWQQDGRDVAFIIGGADGLDAEFKKNADMLIRISSMTLPHGMVRVLLAEQLYRAWSITQNHPYHRV
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_SPHAL
Sequence: MALIAGPTASGKSALAVALAKALGNGTVVNADASQVYADLAILSARPTDDEMQGVPHRLFGHVDGSQAHNAARWADEAQGVIAQAHAAGRVPILVGGTGLYLRTLLYGIAPVPEIDPHIREAVRALPVAQAHAALAEADPAAAARLGPADTTRVARALEVVRSTGRTLASWQQAREGGIADRVALAPLVLLPPRDWLRDRCDVRLVEMFDGGAIDEVEALLARGLDPDLPVMRAIGVPQIAAFLDGTASRDEALAAAQAATRQYAKRQFTWFRHQPPASWPRHIESLSIDIIDNLAIKLRETVLTR
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: RPIA_ECO57
Sequence: MTQDELKKAVGWAALQYVQPGTIVGVGTGSTAAHFIDALGTMKGQIEGAVSSSDASTEKLKSLGIHVFDLNEVDSLGIYVDGADEINGHMQMIKGGGAALTREKIIASVAEKFICIADASKQVDILGKFPLPVEVIPMARSAVARQLVKLGGRPEYRQGVVTDNGNVILDVHGMEILDPIAMENAINAIPGVVTVGLFANRGADVALIGTPDGVKTIVK
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: AROC_VEREI
Sequence: MSGNTFGTLFAVTNFGESHGPAIGCVIDGCPPGMPLSEADIQTDLDRRRPGSSRHVTQRNEPDAVEILSGIYQGQTTGTPIALLIRNTDQRSKDYSRSAESFRPGHADYSYWRKYGIRDPRGGGRSSARLTAPTVAAGAVAKKWLALQYGTRFRACMTQLGELPIPFEHWDHVRNNPFFAPVADVAQYEQYIDALRKAGDSCGARIRVQATGMPVGLGEPLYDKLDADIAYALMGLNAVKGVEIGAGFASVAQRGTVHGDTMTPQGFRSNYAGGVLGGISTGQDLELSIAIKPTSSILSPSASIDIHGHSIEVSTKGRHDPCVGIRATPIAEALLALVVMDHALRHRAQCADVVLPLPPIPAAPA
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: PPAC_STRMU
Sequence: MSKILVFGHQNPDSDAIGSSMAYAYLKRQLGVDAQAVALGNPNEETAFVLDYFGIQAPPVVKSAQAEGAKQVILTDHNEFQQSIADIREVEVVEVVDHHRVANFETANPLYMRLEPVGSASSIVYRLYKENGVAIPKEIAGVMLSGLISDTLLLKSPTTHASDPAVAEDLAKIAGVDLQEYGLAMLKAGTNLASKTAAQLVDIDAKTFELNGSQVRVAQVNTVDINEVLERQNEIEEAIKASQAANGYSDFVLMITDILNSNSEILALGNNTDKVEAAFNFTLKNNHAFLAGAVSRKKQVVPQLTESFNG
What are the official names of this protein?
Probable manganese-dependent inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase class C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDK4_CAEEL
Sequence: MTIRHILAIRKKSLELPSDLKTFLRVLANCQHLKKNKKCRRTIFSVDFQNNQRQKPSNFHFWTVIKKFSKKILKSFIIKFGNNGTIAVVFSIFPTGATPSLTFLFQALGKGAYGNVYRVRSLHDGKDYALKQIMISSKNEGIPQSVLREITVMKHLARKAHPNIISLKSVFHQLDPVRAILKINMIMERCDWDLHTFLRNIPRGVPEQQAKHVTAQIVRALDFLHTHSIIHRDLKPQNILLNRDQTVKLADFGLSKEYSNTTAFTTLVVTLWYRSPEVLLQSYYNSTVDMWALGCIVSEIYCRQPLFVGQNEAEQLTDIFKKMGTPVGKDWPSESVIARDSFPQYRPTNLKDLSPQMSKQAIEFVQQCLRYDHSKRLSARGALSHPFLKPAVATKSRVLKQINFNK
What is the function of this protein?
Serine/threonine-protein kinase which, in association with cyclin D-like protein cyd-1, is required for the progression through the G1 phase of the cell cycle during postembryonic development by phosphorylating and inhibiting lin-35 and fzr-1 (PubMed:10518501, PubMed:11684669, PubMed:25562820).  In complex with cyd-1, involved in sex determination during gonadogenesis by regulating the asymmetric division of the somatic gonadal precursor cell (SGP) (PubMed:16198291).
What are the official names of this protein?
Cyclin-dependent kinase 4 homolog, CDK4/6, Cell division protein kinase 4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.