PharMolix/UniProtQA huggingface dataset:
Protein: RS11_RICAE
Sequence: MNQTVKVKKKKKTITLGVVHIRASFNNTIVTFTDIQGNTIASASAGGNGFKGARKATPYAAQVTIDRASEKAKEYGLKTISIRIGGPGAQRESAMRALFGQNFVVTSILDVSSIAHNGVRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: MURD_BIFLO
Sequence: MQVADKTVVIAGLGVSGTSLAEVLRERGTHVIGVDERKPEADLHSFDDVDWDHVDYVMSSPVFNPRTPFVLEAQRRGIPVMSEVEFAWQLRVNNERTGTPAPWIGITGTNGKTSTTEMTSEMLTACGLDAPTAGNIASGDMSMSLSRCATNPQHDVLCVELSSFQLHFTDSLALDCAAITNIADDHLDWHGGRENYAADKSKVFHNAKRAIVYNAQDAKVSELAAEAQTAEGCRKVGFTLEAPQAGQIGIEDGWIVDRSGVAGGAVGESVRLAAITDFTHLAEPDGSLYPHLVADVLTALALVLGLGADRDTALKALTSFKPGGHRIETVAEAAVEGGSVRFVDDSKATNGHAARASLSSFPAKSVIWIAGGLAKGSRFEDLVKDQAHTIKAAVIIGKDQQPMIEAFASQAPDIPVTIIDPEDNDTVMDRAVEACGTYAAAGDIVLMAPACASMDQFKSYADRGNRFAAAAKTWSEVHGLH
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURL_PARDP
Sequence: MNEPQITEELIAAHGLKPDEYQRILEIIGREPSFTELGIFSAMWNEHCSYKSSKKWLRTLPTTGPQVICGPGENAGVVDIGDGQAVVFKMESHNHPSYIEPHQGAATGVGGILRDVFTMGARPIAAMDALSFGRPEHPKTAHLVKGVVEGIGAYGNAFGVPNVGGEVRFHRSYDGNCLVNAFAAGLADSDKIFYSAASGVGMPVVYLGAKTGRDGVGGATMASAEFDDTIEEKRPTVQVGDPFTEKCLLEACLELMQTDSVISIQDMGAAGLTCSAVEMGDKGGLGIKLVLDAVPQRETNMTAYEMMLSESQERMLMVLKPEKEAEARAIFEKWDLDFAIVGETIAEDRFLIVHGNEVKADLPLSKLSSSAPEYDRPWTPTPAAAEMPALPAIAPIAALKSLIGSPNHAHKGWVWEQYDTQVGADTVRRPGLGAGVVRVHGTQKALAFTSDVTPRYVKANPYEGGKQAVAEAYRNLTACGALPLATTDNLNFGNPEKPEIMGQLVGAIKGIGEACAALDFPIVSGNVSLYNETDGKGILPTPTIGGVGLIADLDDLIAGLPAEGDLALVIGETRGHLGQSALVAEAFGIEAGDAPHVDLTAERRNGEFLRAHGKLVSVATDLSDGGLALAAFELAEAAGLGVTLDSAEIAQLFGEDQARYLVACSEENAAQLVEAAQAAGVPLARVGRFGGEAVAFGGDAAPLAELSQLYRSAFEKSLNLELA
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AP1S2_DICDI
Sequence: MTFHFLLLLSRQGKTRLTKWYSPFTNKEKSRFTREIGNMVLNRPPKLCNFLEWKEYKIIFKRYASLYFVVCCDREDNELIVLEIIHHFVEILDRYFGNVCELDLIFNFHKAYYILDELIMAGELQETSKKTVLRLISQQDTLLEGGPGEHKVDL
What is the function of this protein?
Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes.  The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.  Also involved in early steps of phagocytosis and macropinocytosis.
What are the official names of this protein?
AP-1 complex subunit sigma-2, Adaptor protein complex AP-1 subunit sigma-1B, Adaptor-related protein complex 1 subunit sigma-1B, Clathrin assembly protein complex 1 sigma-1B small chain, Sigma 1B subunit of AP-1 clathrin, Sigma-adaptin 1B, Sigma1B-adaptin.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes small subunit family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle, clathrin-coated vesicle membrane.
Protein: RSGA_PSEPW
Sequence: MAKRQLNRRQNWRIEKIQNERAARAAKREQHALQELEGGDLGPEQLGLVIAHFGVQVEVEAQDGEFAGQVFRCHLRANLPALVTGDRVVWRAGNQGIGVIVAQMPRSTELCRPNNHGQLKPVAANVDLIVIVFAPAPEPHPNLIDRYLVAAEHAGIRPLLLLNKADLINDENGPALHALLEVYRDLGYPLLEVSAHHGDGMQRLQQMLDGHISVFVGQSGVGKSSLVNSLLPAADTRVGDLSEWSGQGTHTTTTARLYHFPNGGDLIDSPGIREFGLGHVSRDDVEDGFIEFRDLFGTCRFRDCKHDREPGCALLEALEDGRIKQQRMNSYRSIIASLPEDSY
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXE_HELPY
Sequence: MKKFLFKQKFCESLPKSFSKTLLALSLGLILLGIFAPFPKVPKQPSVPLMFHFTEHYARFIPTILSVAIPLIQRDAVGLFQVANASIATTLLTHTTKRALNHVTINDQRLGERPYGGNFNMPSGHSSMVGLAVAFLMRRYSFKKYFWLLPLVPLTMLARIYLDMHTIGAVLTGLGVGMLCVSLFTSPKKP
What is the function of this protein?
Removes the 1-phosphate group from tetra- and probably hexaacylated lipid A species, has no requirement for the Kdo moiety of lipid A (PubMed:15489235).  Has no 4'-phosphatase activity (PubMed:15489235, PubMed:16740959).  Has no activity on phospholipids (phosphatidylglycerol, phosphatidylethanolamine or cardiolipin).  This enzyme has to act before EptA can attach phosphoethanolamine to the 1-position of lipid A (PubMed:16740959).  Absence of the 1-phosphate group renders the bacteria partially resistant to host-derived cationic antimicrobial peptides (CAMP), allowing it to camouflage itself from the host innate immune response, and plays a role in the long-term colonization of the host's stomach (By similarity).
What are the official names of this protein?
Lipid A 1-phosphatase.
What is the protein family that this protein belongs to?
Belongs to the lipid A LpxE 1-phosphatase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Activity depends on msbA function when expressed in E.coli, strongly suggesting this protein acts in the periplasm (MsbA flips the lipopolysaccharide precursor across the inner cell membrane).
Protein: GLOV_HELVI
Sequence: VFGTLGSTDDSLFGRYKQDIFNDHRGHLQGQAYGSR
What is the function of this protein?
Antibacterial protein.
What are the official names of this protein?
Gloverin.
What are the subcellular locations of this protein?
Secreted.
Protein: MYMX_HUMAN
Sequence: MPTPLLPLLLRLLLSCLLLPAARLARQYLLPLLRRLARRLGSQDMREALLGCLLFILSQRHSPDAGEASRVDRLERRERLGPQK
What is the function of this protein?
Myoblast-specific protein that mediates myoblast fusion, an essential step for the formation of multi-nucleated muscle fibers (PubMed:28569745, PubMed:35642635).  Involved in membrane fusion downstream of the lipid mixing step mediated by MYMK (By similarity).  Acts by generating membrane stresses via its extracellular C-terminus, leading to drive fusion pore formation.  Acts independently of MYMK (By similarity).  Involved in skeletal muscle regeneration in response to injury by mediating the fusion of satellite cells, a population of muscle stem cells, with injured myofibers (By similarity).
What are the official names of this protein?
Protein myomixer, Microprotein inducer of fusion, Protein minion, hMINION.
What is the protein family that this protein belongs to?
Belongs to the MYMX family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: SYT_ECOSE
Sequence: MPVITLPDGSQRHYDHAVSPMDVALDIGPGLAKACIAGRVNGELVDACDLIENDAQLSIITAKDEDGLEIIRHSCAHLLGHAIKQLWPHTKMAIGPVIDNGFYYDVDLDRTLTQEDVEALEKRMHELAEKNYDVIKKKVSWHEARETFANRGESYKVSILDENIAHDDKPGLYFHEEYVDMCRGPHVPNMRFCHHFKLMKTAGAYWRGDSNNKMLQRIYGTAWADKKALNAYLQRLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQIRDEVNGCIRLVYDMYSTFGFEKIVVKLSTRPEKRIGSDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPVMIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVIMNITDSQSDYVNELTQKLSNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRGKDLGSMDVNEVIEKLQQEIRSRSLKQLEE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCHL1_HUMAN
Sequence: MEPLLLGRGLIVYLMFLLLKFSKAIEIPSSVQQVPTIIKQSKVQVAFPFDEYFQIECEAKGNPEPTFSWTKDGNPFYFTDHRIIPSNNSGTFRIPNEGHISHFQGKYRCFASNKLGIAMSEEIEFIVPSVPKFPKEKIDPLEVEEGDPIVLPCNPPKGLPPLHIYWMNIELEHIEQDERVYMSQKGDLYFANVEEKDSRNDYCCFAAFPRLRTIVQKMPMKLTVNSSNSIKQRKPKLLLPPTESGSESSITILKGEILLLECFAEGLPTPQVDWNKIGGDLPKGRETKENYGKTLKIENVSYQDKGNYRCTASNFLGTATHDFHVIVEEPPRWTKKPQSAVYSTGSNGILLCEAEGEPQPTIKWRVNGSPVDNHPFAGDVVFPREISFTNLQPNHTAVYQCEASNVHGTILANANIDVVDVRPLIQTKDGENYATVVGYSAFLHCEFFASPEAVVSWQKVEEVKPLEGRRYHIYENGTLQINRTTEEDAGSYSCWVENAIGKTAVTANLDIRNATKLRVSPKNPRIPKLHMLELHCESKCDSHLKHSLKLSWSKDGEAFEINGTEDGRIIIDGANLTISNVTLEDQGIYCCSAHTALDSAADITQVTVLDVPDPPENLHLSERQNRSVRLTWEAGADHNSNISEYIVEFEGNKEEPGRWEELTRVQGKKTTVILPLAPFVRYQFRVIAVNEVGRSQPSQPSDHHETPPAAPDRNPQNIRVQASQPKEMIIKWEPLKSMEQNGPGLEYRVTWKPQGAPVEWEEETVTNHTLRVMTPAVYAPYDVKVQAINQLGSGPDPQSVTLYSGEDYPDTAPVIHGVDVINSTLVKVTWSTVPKDRVHGRLKGYQINWWKTKSLLDGRTHPKEVNILRFSGQRNSGMVPSLDAFSEFHLTVLAYNSKGAGPESEPYIFQTPEGVPEQPTFLKVIKVDKDTATLSWGLPKKLNGNLTGYLLQYQIINDTYEIGELNDINITTPSKPSWHLSNLNATTKYKFYLRACTSQGCGKPITEESSTLGEGSKGIGKISGVNLTQKTHPIEVFEPGAEHIVRLMTKNWGDNDSIFQDVIETRGREYAGLYDDISTQGWFIGLMCAIALLTLLLLTVCFVKRNRGGKYSVKEKEDLHPDPEIQSVKDETFGEYSDSDEKPLKGSLRSLNRDMQPTESADSLVEYGEGDHGLFSEDGSFIGAYAGSKEKGSVESNGSSTATFPLRA
What is the function of this protein?
Extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity.  Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death.  Plays a role in neuronal positioning of pyramidal neurons and in regulation of both the number of interneurons and the efficacy of GABAergic synapses.  May play a role in regulating cell migration in nerve regeneration and cortical development.  Potentiates integrin-dependent cell migration towards extracellular matrix proteins.  Recruits ANK3 to the plasma membrane (By similarity).
What are the official names of this protein?
Neural cell adhesion molecule L1-like protein, Close homolog of L1.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=Soluble forms produced by cleavage/shedding also exist. SUBCELLULAR LOCATION: [Processed neural cell adhesion molecule L1-like protein]: Secreted, extracellular space, extracellular matrix.
Protein: AC4CH_VIBCM
Sequence: MSISTQITFFEFLTPLVASGQKTITIRDKSESHYVPGTRVEVFTLETQRKVCEIDILAVEPLKFDEINEFHAEQEAIELPKLKALIQEIYPNIDELYVITYQLAK
What is the function of this protein?
Catalyzes the hydrolysis of N(4)-acetylcytidine (ac4C).
What are the official names of this protein?
N(4)-acetylcytidine amidohydrolase, ac4C amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the N(4)-acetylcytidine amidohydrolase family.
Protein: SYN_HAEIE
Sequence: MSKVASIVDVLQGKVAIGETVTVRGWVRTRRDSKAGLSFLAVYDGSCFDPIQAIINNDIKNYESEILRLTTGCSVIVTGKVVESPSEGQAVELQAEKVEVTGFVEDPDTYPMAAKRHSIEYLREVAHLRPRTNIIGAVSRVRHCLSQAIHRFFHEQGFYWVATPLITASDTEGAGEMFRVSTLDLENLPRSENGKVDFSQDFFGKESFLTVSGQLNGETYACALSKIYTFGPTFRAENSNTTRHLAEFWMVEPEVAFATLADNAKLAEDMLKYVFRAVLAERKDDLQFFEKHVDKDVITRLENFVNSDFAQIDYTDAIDVLLKSGKKFEFPVSWGIDLSSEHERFLAEEYFKSPVVVKNYPKDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERLEVLDKRMEEMGLNPDDYWWYRDLRKYGSVPHSGFGLGFERLIVYVTGVQNIRDVIPFPRAPRNANF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_ACAM1
Sequence: MSEVIKSISVDGREIKLTIGRFAPQAGGCVLIESGETSVLVTATRSSGREGIDFLPLLVDYEERLYAAGRVPGGFLRREGRPPEKATLTCRLIDRPMRPLFPNWLRDDLQIVATTISMDEQVPPDVLAVTGASVATLLAKIPFKGPMAAVRVGLVGDDFIINPTYEEISEGELDLVVAGSPDGVIMVEAGANEVAEQDMIEAIDFGYEVVCDLIKAQKELIAELGIEQVEEAAPETDPTLENFVQERVTDPVKDVLARFEKDKNVRDAALDEIKESVKVAIDELPETDPVQVAAVENPKAIGKVFKSITKTLMRRQVVEDKVRVDGRKLDEVRPISCNVGVLPQRVHGSGLFNRGLTQVLSIATLGTPGDAQEMDDLHPDSQKRYLHHYNFPPYSVGETRPMRSPGRREVGHGALAERALLPMLPSKEEFPYVLRVVSEVLSSNGSTSMGSVCGSTLSLMDAGVPLAKPVSGAAMGLIKEGEEVRVLTDIQGIEDFLGDMDFKVAGTADGITALQMDMKITGLSMKVIAEAIHQAKPARLHILDKMLATIDSPRETMSPYAPRLLTIKIDPEQIGMIIGPGGKTIKGITEETGAKIDIEDDGRVTISAVDEKAASRARQIIAGMTRKLAAGDVFLGKVTRIIPIGAFVEIAPSKEGMIHISQLADYRVGKVEDEVTVGDEVVVKIRELDNRGRINLTRLGIHPEEAAAARAGGSES
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXD_BARHE
Sequence: MADTFFFTPSRRLTVANVAELTGAKLLNPEFSNTVINTLSSLESAGKGSLVFVEHRKFSDALVGSSAVAVFCTNEIVFKVPESMAILVTSTPQRDFAQIGRILFPDSVKPMPWFGQREISPHAHIHPSAKLAGDVCIEAGAVIGRNVEIGSGSLIASTAVIGENCRIGCDCYIAPKVTVQYSLIGDKVHLYPGACIGQDGFGYIGGASGIEKVPQLGRVIIEDGVEIGANTTIDRGTFEDTIIGEGSKIDNLVQIAHNVKIGRYCLIAAQCGIAGSTSIGDMSQLGGSVGVADHIVIGKYVQIAAGSGVMNDIPDGEKWGGSPARPFKQWFREVAALRSIGKVKKEKR
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: RPOA_BURMS
Sequence: MQTSLLKPKIIAVESLGENHAKVVMEPFERGYGHTLGNALRRVLLSSMVGYAPTEVTIAGVVHEYSTLDGVQEDVVNLLLNLKGVVFKLHNRDEVTVTLRKEGEGVVTAGDIELAHDCEVINPNHVIAHLSKGGKLDVQIKVEKGRGYVPGNVRRYGDETAKIIGRIVLDASFSPVRRVSYTVESARVEQRTDLDKLVMNIETSGVITPEEAIRQSARILVDQLSVFAALEGTETAAEAPSRAPQIDPILLRPVDDLELTVRSANCLKAENIYYIGDLIQRTENELLKTPNLGRKSLNEIKEVLASRGLTLGMKLENWPPAGLDK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: EIF3I_RABIT
Sequence: MRPILLQGHERSITQIKYNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCRLWDCETGKQLALLKTNSAVRTCGFDFGGNIIMFSTDKQMGYQCFVSFFDLRDPSQIDNNEPYMKIPCNDSKITSAVWGPLGECIIAGHESGELNQYSAKSGEVLVNVKEHSRQINDIQLSREMTMFVTASKDNTAKLFDSTTLEHQKTFRTEPPRELAALSPNYEHVVVGGGQEAMDVTTTSTRIGKFEARFFHLAFEEEFGRVKGHFGPINSVAFHPDGKSYSSGGEDGYVRIHYFDPQYFEFEFEAREAGSPSG
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis.  The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC).  The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition.  The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit I, eIF3i, Eukaryotic translation initiation factor 3 subunit 2, eIF-3-beta, eIF3 p36.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit I family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE_RHOPB
Sequence: MTLPVVTRFAPSPTGFLHIGGARTALFNWLYAKKRGGKMLLRIEDTDRERSTQAAIDAILDGLKWLELGWDGDVVYQYANAARHREVVDEMLAAGTAYRCYASAEELAQMRESAKAEGRTRFYNGLWRDRDPSDAPAGVKPTVRLKAPLTGETVIEDQVQGRVVWQNDNLDDLVLLRGDGSPTYMLAVVVDDHDMGVTHVIRGDDHLINAARQKQIYDALGWEIPSMSHIPLIHGPDGSKLSKRHGALGVDAYRAMGYLPAALRNYLVRLGWSHGDQEIFSTEEMIEAFDLPAIGRSAARFDFAKLENLNGHYIRHADDQSLVTMLEDVLRYIPHGDEIAAKINDTTRAQLLQAMPGLKERAKTLLELIHSADFILADRPLPIEPKAQAVLTPDTRKLIAQLRAALETVTSWSAATTEAAMRAFAEQHGLKLGAVAQPLRVALTGRTTSPGIFDVLAVLGRQECLSRLADQASE
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLIE_HYDCU
Sequence: MSNSVDTQSLMLQMRSLAAEAASQSQSVQKVEKGAQSAENFSDLLSQSVNAVATEQNKSSAMKTAFEKGEDVDLTEVMVQAQKASLSFQAMTQVRNKLVEAYKDIKNMPI
What are the official names of this protein?
Flagellar hook-basal body complex protein FliE.
What is the protein family that this protein belongs to?
Belongs to the FliE family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: MINE_SYNR3
Sequence: MTLREMIDRLLGRQQASATTAKHRLQLVLAHDRSDLNPDLMEQMRREILEVVNRYVELDLEGGDVSLETEERATALVANLPIRRVRDDVLPQVPAVQ
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: NADK_LEIXX
Sequence: MAAQRYILVVAHTGRRDSLAAGVSVCRQLLAAGVVPVLSEGERRDLLAAEPELATVVALGAEVPPAELELVIVLGGDGTILRAAELVRGCPAPLLGVNLGHVGFLAESERDDLETAVARGLAKDYEVEERMTLSARVKVGEEVVYESWALNEATVEKANRERVLEVVIEADGRPMSSFGCDGVVMSTPTGSTAYSFSAGGPVVWPGVAALLLVPLSAHALFSRPLVVDADSSLAVELLEGAGGEGVLWCDGRRAFDLPRGARVVVRRSPIPVRLARLHPGPFTDRLVRKFTLPVTGWRGPDGRD
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_ECODH
Sequence: MLAKRIIPCLDVRDGQVVKGVQFRNHEIIGDIVPLAKRYAEEGADELVFYDITASSDGRVVDKSWVSRVAEVIDIPFCVAGGIKSLEDAAKILSFGADKISINSPALADPTLITRLADRFGVQCIVVGIDTWYDAETGKYHVNQYTGDESRTRVTQWETLDWVQEVQKRGAGEIVLNMMNQDGVRNGYDLEQLKKVREVCHVPLIASGGAGTMEHFLEAFRDADVDGALAASVFHKQIINIGELKAYLATQGVEIRIC
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YDBJ_ECOL6
Sequence: MRAAFWVGCAALLLSACSSEPVQQATAAHVAPGLKASMSSSGEANCAMIGGSLSVARQLDGTAIGMCALPNGKRCSEQSLAAGSCGSY
What are the official names of this protein?
Uncharacterized protein YdbJ.
Protein: NUOK_PSEU2
Sequence: MNAIPLEHGLAVAGVLFCLGLVGLMVRRNILFVLMSLEIMMNAAALAFVVAGSRWGQPDGQVMFILVISLAAAEASIGLAILMQLYRRFHTLDIDAASEMRG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KTHY_AKKM8
Sequence: MSFTGERKGRLIVFEGIDGTGKSTHIGHLRKYLEEKELEVVQSFEPTRGRWGRMLRDSAVTGRLSVEEEVALFLKDRREHVKMLIAPALARGAWVLLDRYYLSMMAYQGARGIDPEVIRAANEEFAPVPDAVVWLDIPVSVALERIGNRGERDAFETEAGLAACRSVFASVHAPWMLRIDADAGKEEVAARVRKALSMRFPDVIGA
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.