PharMolix/UniProtQA huggingface dataset:
Protein: DNAJ_LYSSH
Sequence: MEKRDYYEVLGLTKDEIKKAYRKLSKQYHPDLNKEPGADEKFKEIAEAYEVLSDDQKKARYDQFGHEDPNAGFGGGFGGGGFGGFEDIFSSFFGGGGRRQDPNAPRKGDDLQYRMNIKFEEAIFGKETEIEIPKDETCETCHGSGAKPGTQPETCSTCNGAGQINQAVDTPFGRMMNRRSCTTCHGTGKIIKEKCSTCRGEGKVQKRKKIKVSIPAGVDDGQQIRVSGQGEPGINGGPAGDLYIMFRVQGHNDFERDGDDIYFELKLTFPQAALGDEIEVPTVHGKVKLRIPAGTQSGAQFRLKDKGVKNVHGYGMGNQYVTVKVMTPEKLTEKQKQLLREFAEISGDIPEEQGSSLFDKIKKKFQGE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 18K1_MYCIT
Sequence: MLMRSDPFRELDRFAHQVLGTAARPAVMPMDAWRQGEEFVVEFDLPGIDADSLDIDIERNVVTVRAERPALDPNREMLATERPRGVFSRQLVLGENLDTDKIQASYSEGVLSLHIPVAEKAKPRKIAVGRGDGHHAVAEGAAQREVINA
What is the function of this protein?
Not known.  This protein is one of the major immune reactive proteins in mycobacteria.
What are the official names of this protein?
18 kDa antigen 1, 18 kDa antigen clone MINTC73.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
Protein: MHPB_MYCPA
Sequence: MALALCCMSHSPLLNLPGPSRDLLDDIDAAIARARGFVEDYDPQLVVIFSPDHYNGFFYKVMPPFCIGSSASGVGDYGTHAGPLDVPEKLAVDCAQAVLDAGVDIAVSASMDVDHGTVQPLEKLFGTAISRPVIPVFVNAIGVPLGPMHRCRALGAAVGTYLATLDKRVLVMGSGGLSHSPPVPTLATAPEPVLQRIVHGAPMTAEQRQARQAAVIDAARSFAAGDSALQPLNPTWDHRFLEIIDRGSLSELDRWSNSFVTHEGGGSAHEIRTWVAAFAALQAAGPYETTMRYYTPAPELIAGFAIRTARPK
What is the function of this protein?
Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6-ketononatrienedioate, respectively.
What are the official names of this protein?
2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase, 3-carboxyethylcatechol 2,3-dioxygenase.
What is the protein family that this protein belongs to?
Belongs to the LigB/MhpB extradiol dioxygenase family.
Protein: DXS_ECO8A
Sequence: MSFDIAKYPTLALVDSTQELRLLPKESLPKLCDELRRYLLDSVSRSSGHFASGLGTVELTVALHYVYNTPFDQLIWDVGHQAYPHKILTGRRDKIGTIRQKGGLHPFPWRGESEYDVLSVGHSSTSISAGIGIAVAAEKEGKNRRTVCVIGDGAITAGMAFEAMNHAGDIRPDMLVVLNDNEMSISENVGALNNHLAQLLSGKLYSSLREGGKKVFSGVPPIKELLKRTEEHIKGMVVPGTLFEELGFNYIGPVDGHDVLGLITTLKNMRDLKGPQFLHIMTKKGRGYEPAEKDPITFHAVPKFDPSSGCLPKSSGGLPSYSKIFGDWLCETAAKDNKLMAITPAMREGSGMVEFSRKFPDRYFDVAIAEQHAVTFAAGLAIGGYKPIVAIYSTFLQRAYDQVLHDVAIQKLPVLFAIDRAGIVGADGQTHQGAFDLSYLRCIPEMVIMTPSDENECRQMLYTGYHYNDGPSAVRYPRGNAVGVELTPLEKLPIGKGIVKRRGEKLAILNFGTLMPDAAKVAESLNATLVDMRFVKPLDEALILEMAASHEALVTVEENAIMGGAGSGVNEVLMAHRKPVPVLNIGLPDFFIPQGTQEEMRAELGLDAAGMEAKIKAWLA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: ALLA_SHIB3
Sequence: MKLQVLPLSQEAFSAYGDVIETQQRDFFHINNGLVERYHDLALVEILEQDRTLISINRAQPANLPLTIHELERHPLGTQAFIPMKGEVFVVVVALGDDKPDLSTLRAFITNGEQGVNYHRNVWHHPLFAWQRVTDFLTIDRGGSDNCDVESIPEQELCFA
What is the function of this protein?
Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate.  Involved in the anaerobic utilization of allantoin as sole nitrogen source.  Reinforces the induction of genes involved in the degradation of allantoin and glyoxylate by producing glyoxylate.
What are the official names of this protein?
Ureidoglycolate lyase, Ureidoglycolatase.
What is the protein family that this protein belongs to?
Belongs to the ureidoglycolate lyase family.
Protein: UREG_PARXL
Sequence: MNAPHHPAHSTVRTKKLPPLRVGVGGPVGSGKTTLLEMLCKAMREQYDLVAITNDIYTKEDQRLLTVAGALPAERIMGVETGGCPHTAIREDASINLEAVDRMLTRFPDADIVFIESGGDNLAATFSPELSDLTIYVIDVAGGEKIPRKGGPGITKSDLLVINKTDLAPMVGANLEVMAADAKKMRGERPFVMCNLKALDGLDVVVKFIEKKGLLKV
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GGAG_MLVFP
Sequence: LGDVPGTSGAIFVARPESNYPDRFGLFGAPPLEEGYVILVGDGRLKRFPPPSEFLLSVWSRSRAARPVCCSIVLCCFCLTVFLYLSENMGQTATTPLSLTLDHWKDVERTAHNQSVEVRKRRWVTFCSAEWPTFNVGWPRDGTFNPDIITQVKIKVFSPGPHGHPDQVPYIVTWEALAVDPPPWVKPFVHPKPPLLLPPSAPSLPPEPPLSTPPQSSLYPALTSPLNTKPRPQVLPDSGGPLIDLLTEDPPPYRDPGPPSPDGKGDSGEVAPTEGAPDSSPMVSRLRGRREPPVADSTTSQAFPLRLGGNGQFQYWPFSSSDLYNWKNNNPSFSEDPGKLTALIESVLLTHQPTWDDCQQLLGTLLTGEEKQRVLLEARKAVRGEDGRPTQLPNDINDAFPLERPDWDYNTQRGRNHLVHYRQLLLAGLQNAGRSPTNLAKVKGITQGPNESPSAFLERLKEAYRRYTPYDPEDPGQETNVSMSFIWQSAPDIGRKLERLEDLKNKTLGDLVREAEKIFNKRETPEEREERVRRETEEKEERRRAEDERREKERDRRRHREMSKLLATVVSGQRQDRQGGERRRPQLDHDQCAYCKEKGHWARDCPKKPRGPRGPRPQASLLTLDD
What is the function of this protein?
Plays a role in viral particle release.  Presumably acts by facilitating the fission of the virion bud at the cell surface.  May prevent the antiviral activity of murine APOBEC3.
What are the official names of this protein?
Glyco-Gag protein, Gross cell surface antigen, glycosylated Pr80 gag, gPr80 Gag, gag-gPr80.
What are the subcellular locations of this protein?
Host cell membrane; Single-pass membrane protein.
Protein: MUTS_ALCBS
Sequence: MTADLSQHTPMMQQYLGIKAEHPDQLVFYRMGDFYELFFGDAQKAARLLDITLTQRGQSAGKPIPMAGIPYHAAENYLARLVKLGESVAIAEQIGDPALAKGPVERKVVRIVTPGTVSDEALLEERRDNLLCAVFDHNNQYGCASLDLAAGRFLVTQVEGAEQLQALLERWSPAELLISEEHGLPGRWSDRPGTRKRPSWEFDEDAARRQLCQQFQVQDLAGFGEPSPVAVSAAGALLGYAKETQRGELPHITGLTVESFDDAVAMDAATRRNLELTETLDGQEQHTLAWVLDSTKTAMGARLLKRWVHQPLRNRTTLTQRQDQIDALRQGWCFESARDVLNDIGDMERILGRVALRSARPRDLTRLHASLKALPPLIGTLPAADCFCELIERIGQFPNQVELLGTAVIENPPMLIRDGGVIAPGYSEELDELRSISENAGAILVDIETRERERTQLSTLRVKYNRVHGYYIELSRRESDQAPTDYQRRQTLKNAERFITPELKEFEDKALSASSKALALEKRLYEALLEKVAADLHALQRSAAAVAELDVLASLAERAEALNWVLPQLVDDEAIIEIVDGRHPVVEQVLDDAFVPNSLHLDNARRMVIITGPNMGGKSTYMRQTALIALLAHLGSCVPAASARIGSLDRIFTRIGSSDDLAGGRSTFMVEMSETANILNNATAQSLVLMDEIGRGTSTFDGLSLAWAAAEHLARNLKSFTLFATHYFELTQLPEQLPGIYNAHLTASEHDNRIVFLHRVQEGPASRSYGLQVAQLAGVPSSVIHRAGEKLRELEQSKPLAPSATPPSSYAAPSPAAAPAQASLFNEPNAIELALTDLDPDELTPKQALEALYTLKKLT
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: FB80_ARATH
Sequence: MASPTLALAQSPPPKSPAVSVSQRNPHCWSKLPLDLMQLVFERLAFLDFERAKSVCSSWQFGSKQSKPNNQIPWMILFPTDKNYCLLFNPEDKEKLYKTQHLGDDFAKSIVLATYRSWLLMQPRYEELEDQTLDQEFHLYIKDLLTCERINLPAFESDIFGLSHPILWIDDKTKDYLVIGTINRETMVSFKNGDNSWKKFPELPKSSCTDMCLNMIYKDHKLHYLDYSNLYIYDFFGEFPREAFRISVREFVGYATNPYGYDEFPEVPLKLKLNRYIYNMIVTVRGDVLIVASLHFSMAETWEFIICKMDSSKVNKWEEIVSLGDESILLGLGITVLAKDMEGITCNSIYFTADDFYEDYEENEIFIYNLDTNKVEIPHQFVSSSIPSAHARWFLPTFKRD
What are the official names of this protein?
F-box protein At1g69090.
Protein: TRMD_SHEHH
Sequence: MWLGVVTLFPEMFRAVTDFGVTGRAVSKGLLELQTWNPRDFTHDKHKTVDDRPYGGGPGMLMMVQPLRDAIHAAKAAAGKEAKVIYLSPQGRKLTQQGVEELAKSSSLVLVCGRYEGVDERIIQTEVDEEWSIGDYVLSGGELPAMTLIDSVSRLVPGVLGKQASAEQDSFSDGLLDCPHYTRPESLDGLDVPAVLLSGNHEHIRRWRLQQSLGRTLLRRPELLENLALTGEQEKLLADFVDTIKQDD
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTC_MYCBO
Sequence: MIRHFLRDDDLSPAEQAEVLELAAELKKDPVSRRPLQGPRGVAVIFDKNSTRTRFSFELGIAQLGGHAVVVDSGSTQLGRDETLQDTAKVLSRYVDAIVWRTFGQERLDAMASVATVPVINALSDEFHPCQVLADLQTIAERKGALRGLRLSYFGDGANNMAHSLLLGGVTAGIHVTVAAPEGFLPDPSVRAAAERRAQDTGASVTVTADAHAAAAGADVLVTDTWTSMGQENDGLDRVKPFRPFQLNSRLLALADSDAIVLHCLPAHRGDEITDAVMDGPASAVWDEAENRLHAQKALLVWLLERS
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline, which is a substrate for argininosuccinate synthetase, the enzyme involved in the final step in arginine biosynthesis.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIM24_TALSN
Sequence: MRLTLGKGATAVYRARAGVSVSSPLYRRHGVRNVQIKAAPLGEPTIVNGVNLPISSTPSSASSADAKFHVVGTPYSMLSVSLSASQNLYTQRGTLVGLSGKADNVISTLSVLEPSRRAIVGIPFLYQKISSPSPIKALVSVRSPVTSFAVVHLDGTVDWMVAQRRALLAWTGHSLKIKPRINTNLSVTNWGSSEVTGRGLLALVGRGQVYSVELKAGEQYIAHPSNIVAYTLSSTRPQPYRFKSTTLRFQIPGLQIPELLLKSRYVRDLTASDTWKASMKLIHNFRTWARRTIWGDRLFLQFNGPATLLIQSRGARVRDIMSDKEVNEIADTPTGATLDAINKLEARTSPSTNENDKIDYQRAAEEAVSQAPGPSRTVEGLTQEIKGVSQTIATIRDGKVEFEKLKQQNAEIARK
What are the official names of this protein?
Altered inheritance of mitochondria protein 24, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AIM24 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: APCB1_ARATH
Sequence: MEPDLHDQQQQQRVHSVVIITLPPSDDPSQGKTISAFTLTDHDYPLEIPPEDNPNPSFQPDPLHRNQQSRLLFSDLSMNSPRLVLGLLGISLLAVAFYASVFPNSVQMFRVSPDERNRDDDDNLRETASFVFPVYHKLRAREFHERILEEDLGLENENFVESMDLELVNPVKVNDVLSTSAGSIDSSTTIFPVGGNVYPDGLYYTRILVGKPEDGQYYHLDIDTGSELTWIQCDAPCTSCAKGANQLYKPRKDNLVRSSEAFCVEVQRNQLTEHCENCHQCDYEIEYADHSYSMGVLTKDKFHLKLHNGSLAESDIVFGCGYDQQGLLLNTLLKTDGILGLSRAKISLPSQLASRGIISNVVGHCLASDLNGEGYIFMGSDLVPSHGMTWVPMLHDSRLDAYQMQVTKMSYGQGMLSLDGENGRVGKVLFDTGSSYTYFPNQAYSQLVTSLQEVSGLELTRDDSDETLPICWRAKTNFPFSSLSDVKKFFRPITLQIGSKWLIISRKLLIQPEDYLIISNKGNVCLGILDGSSVHDGSTIILGDISMRGHLIVYDNVKRRIGWMKSDCVRPREIDHNVPFFQG
What is the function of this protein?
Involved in proteolytic processing of BAG6 and plant basal immunity.
What are the official names of this protein?
Aspartyl protease APCB1, Aspartyl protease cleaving BAG 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SUFS_ECO45
Sequence: MTFSVDKVRADFPVLSREVNGLPLAYLDSAASAQKPSQVIDAEAEFYRHGYAAVHRGIHTLSAQATEKMENVRKRASLFINARSAEELVFVRGTTEGINLVANSWGNSNVRAGDNIIISQMEHHANIVPWQMLCARVGAELRVIPLNPDGTLQLETLPTLFDEKTRLLAITHVSNVLGTENPLAEMITLAHQHGAKVLVDGAQAVMHHPVDVQALDCDFYVFSGHKLYGPTGIGILYVKEALLQEMPPWEGGGSMIATVSLSEGTTWTKAPWRFEAGTPNTGGIIGLGAALEYVSALGLNNIAEYEQNLMHYALSQLESVPDLTLYGPQNRLGVIAFNLGKHHAYDVGSFLDNYGIAVRTGHHCAMPLMAYYNVPAMCRASLAMYNTHEEVDRLVTGLQRIHRLLG
What is the function of this protein?
Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules.  Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation.  Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine.  Selenocysteine lyase activity is however unsure in vivo.
What are the official names of this protein?
Cysteine desulfurase, Selenocysteine beta-lyase, SCL, Selenocysteine lyase, Selenocysteine reductase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPIA_HALMA
Sequence: MKQGGSDAAKQAAGESAAEAVEDATVVGLGTGSTAAYAIRAIGQAVDAGLDVVGVPTSFQSRQLARDCGIPLADLDDVSVDLAIDGADEVASGNLIKGGGAAHAREKIVDASADRFLVVADPTKEAAVLSYPVPVEVLPMARSTVVTAVEELGGDPTLRRAERKDGPVVTDNGNLVLDCDFNSIHDPAALASDLAALPGVVEHGLFVGMADEIHVGTADGVTVRTLSK
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: XERC_XANCB
Sequence: MPEAAPPVADARGSSPTATTGPGADATLSAVEPFLAHLQIERQVSAHTLDAYRRDLAALIGWASAQGSEDVAQLDSAQLRKFVTAEHRRGLSPKSLQRRLSACRSYYAWLLKHGRIATSPAAALRAPKAPRKLPQVLDADEAVRLVEVPTDAPLGLRDRALLELFYSSGLRLSELCALRWRDLDLDSGLVTVLGKGGKQRLVPVGSHAVAALRAWQRDSGGSAQTHVFPGRAGGAISQRAVQIRIKQLAVRQGMFKHVHPHMLRHSFASHILESSGDLRGVQELLGHSDIATTQIYTHLDFQHLAKVYDAAHPRAKRKKATE
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: END4_MYCMM
Sequence: MLIGSHVSPQDPLAAAQAEGAEVVQIFLGNPQSWKAPKPREDAAQLKAAALPIYVHAPYLINLASANNKVRIPSRKILQQTCDAAADIGAAAVIVHGGHVADDNDLDEGFQRWRKALDQLQTDVPVYLENTAGGEHAMARHFDTIARLWDVIGDTGIGFCLDTCHAWAAGEQLVHGVDRIKAVTGRIDLVHCNDSRDAAGSGRDRHANLGAGQIDPELLVAAVRAADAPIICETAEEGRKDDIAFLREKLNS
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: HEM1_RIPO1
Sequence: MNIAVVGLSHKTAPVEVREKLSIQEAKLEEALTHLRGYPHIEEVAIISTCNRLEIYAVVSDTEKGVVEITQFLSETGHLPLNYLRRYLFTLLHQDAVRHLLRVAAGLESLVLGEGQILAQVKTTHKLGQKYKGIGRLLDRLFKQAITAGKRVRSETNIGTGAVSISSAAVELAQTKAEDLANRRISIIGAGKMARLLVQHLLSKGATDITIVNRSHHRAQELAAQFPQASLNLQLLPEMMQVVASSHIVFTSTAATEPILHRENLTAALDPNHALMLFDISVPRNVASDVHGMEGIESYNVDDLKAVVAQNYESRRQMAQEAEGLLEEEVEAFDLWWRSLETVPTISCLRTKVETIREQELEKALSRLGTEFAEKHQEVIEALTRGIVNKILHEPMVQLRAQQDIEARKRCLESLKMLFDLEIEEQFG
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: GUAC_EDWI9
Sequence: MRIEEDLKLGFKDVLIRPKRSTLKSRSDVELAREYRFKHSGWQWSGVPLIAANMDTVGTFSMARVLAGFDVLTAVHKHYSVEQWQSFVSSVGEETLRHVMVSTGTSEADFIKLRQILALSPSLKFICIDVANGYSEHFVDFLRRARDVCPDKVICAGNVVTGEMVEELILSGADIVKVGIGPGSVCTTRVKTGVGYPQLSAVIECADAAHGLGGQIVSDGGCTMPGDVAKAFGGGADFVMLGGMLAAHAECEGRIVEEQGRKMMLFYGMSSASAMNRHVGGVADYRAAEGKTVSLPLRGPVENTVRDILGGLRSACTYVGASRLKELTKRTTFIRVAEQENRVFGRAD
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
Protein: MTMRD_XENLA
Sequence: MARLADYFIVVGYDHEKTGSEGFGKIIQRFPMTDWSDTPFPQGIELFCQPGGWQLSRERKQPTFFIVVLTDIDSDRHYCACLTFYEAEINLQGTKREHSETEEEDSGLIQPAQVFAPKSLVLVSRLDYPEIFRACLGLIYTVYIDSLNVSLENLVSNLVTCIVPCAGGSQKLFSLGAGDRQLIQTPLHDSLPVTGTSVALLFQQLGIQNVLSLFCAVLTENKVLFHSSSFQRLGDACRALEALIYPLKYSYPYIPILPAQLLEVLSSPTPFIIGVHSVFCSEIHDLLDVIIADLDGGTIKIPECIHLSPIPEPLLHQTQAALSLVLHPDLEVADNAFAPLRTPVPHIKLLDKEVRAVFLRLFAQIFQGYRSCLQLIRIHAEPIIHFHKAAFLGQRGLIENDFLTKVLSGMSFAGFVSERGPPYRPCDLFDELVSFEVERIKDDDQNDTHKILKHIRELAEQLFKNENPNPHMAFQKVPKPTEGSHLRVHILPFSKMNDLKVQELIQEGLNKNQNSILSPRAEKKCVVPAGSPVVSIVDKASSVFNSARRLEVVRNCIMYIFENKTLETEKTLPAALRALKGKAARQCLTEELALHVQQNRSMLNHQQFDYIVRMMNCALQDCSGSEEYTIASQLLPLATAFCRKLSAAVSQFAYTCVQDHGVWANQQFWETTFYNDVQNQVRSLYLTTKNGNQGASEPKENGVDSGNPERTVMDLAAEQLRLWPTLSKETQQELIQSEESTVFSQAIHFANLMVYLLVPLDTSKNKLLRTSATGDWESGSNSIVTNSIAGSVAESYDTESGFEDSENDIANSVVRFITRFIDKVCTESGVTQDHIKSLHCMIPGIVAMHIETLEAVHRESRRLPPIKKPKIMRPALLPGEEFVCEALRVLLDPDGREEATGGMLGGPHILPAEGALFLTTYRIIFKGTPHDALVGEQTVIRSVPIASITREKKINVQNQLHQNMQEGLQIRSATFQLIKVAFDEEVSAEMVDLFKKQLMKFRYPLSIFSAFAFAAGQTAPPIILPKQKEKNTSFRTISKTIVKGAKRAGKMTIGRQYAAKKKTGTILEERGSRSGGNEDDDISVSDDNELPSGTLKPSEKSTMEQLVERACFRDYQRLALGTISNSSTRFKSEHFRVTALNRMHSLCRSYPGLLVVPQSVQDSSLQKVARCYRHNRLPVVSWKNAKTNAVLLRGGGFHGKTVVGLFKSQNTHTAAPASSLESSSSIEQEKYLQALLNAISVHYKMNGNSTLTVRPTLALSPGSDRKSSRMSSVVKHVVPSHVDGSLSHSFARGGVWASLRSSNRLITTQTPLIDVGARLVGKDLQTTYTDHSALQSQLLKRQAALYIFGEKSQLRGFKFDFALNCEFVPVEFGDIRQVKTSFKKLMRACVPSSNPTDSESTFLKAMGESEWFLQIHRIIQLSVIISELMESGSSVMICLEDGWDITTQVVSLVQILGDPFYRTLEGFRMLIEKEWLSFGHKFSQRSNLSPSSQGTGFVPIFLQFLDCVHQIHNQYPTEFEFNRYYLKFLAYHHVSNRFKTFLLDSDYERLEHGTLFEDKGDKHSRRGICIWEYIERIHKKKTVFFNYLFAPTELEALKPSANISTLRKWEYYMEETLASGPSYDWIITPSRFNASDETDSGEEAQQQGKRKIVWPCYDDVQKVQPDAITHLMNEIERLEIKLNQTSERWQLLWERAKVKLKENAKKENNNPASLVSANLQSYQKRSMVHLPDSGLGDEQNLNASPSNGVDRRTATLYNHFTSKNEENRSYEGILYKRGALLKGWKPRWFVLDITKHQLRYYDSGEDTSCKGYIDLADVETVVPAAPTIGAPKHANEKAFFDVKTSKRVYNFCAQDAQSAQLWMDKIQNCISDA
What is the function of this protein?
Guanine nucleotide exchange factor (GEF) which may activate Rab small GTPases (By similarity).  Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form (By similarity).  Acts as an adapter for the phosphatase mtmr2 (By similarity).
What are the official names of this protein?
Myotubularin-related protein 13, Inactive phosphatidylinositol 3-phosphatase 13, SET-binding factor 2.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein. Note=Associated with membranes.
Protein: SCAF_SCMVC
Sequence: MADPVYVGGFLVRYDEPPGEAELFLPSGVVDRWLRDCRGPLPLNVNHDESATVGYVAGLQNVRAGLFCLGRVTSPKFLDIVQKASEKSELVSRGPPSESSLRPDGVLEFLSGSYSGLSLSSRRDINAADGAAGDAETACFKHVALCSVGRRRGTLAVYGRQPDWVMERFPDLTEADREALRNQLSGSGEVAAKESAESSAAAAVDPFQSDSYGLLGNSVDALYIQERLPKLRYDKRLVGVTARESYVKASVSPAEQETCDIKVEKERPKEPEQSHVPTESMSHPMSAVATPAASTVAPSQAPLALAHDGVYLPKDAFFSLIGASRPLAEAAGARAAYPAVPPPPAYPVMNYEDPSSRHFDYSAWLRRPAYDAVPPLPPPPVMPMPYRRRDPMMEEAERAAWERGYAPSAYDHYVNNGSWSRSRSGALKRRRERDASSDEEEDMSFPGEADHGKARKRLKAHHGRDNNNSGSDAKGDRYDDIREALQELKREMLAVRQIAPAALLAPAQLATPVASPTTTTSHQAEASEPQASTAAAAPSTASSHGSKSAERGVVNASCRVAPPLEAVNPPKDMVDLNRRLFVAALNKME
What is the function of this protein?
Plays a major role in capsid assembly.  Acts as a scaffold protein by binding major capsid protein.  Multimerizes in the nucleus such as major capsid protein forms the icosahedral T=16 capsid.  Cleaved by assemblin after capsid completion.  The cleavages products are evicted from the capsid before or during DNA packaging.
What are the official names of this protein?
Capsid scaffolding protein, Capsid protein P40, Protease precursor, pPR.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae capsid scaffolding protein family.
What are the subcellular locations of this protein?
[Capsid scaffolding protein]: Host cytoplasm. SUBCELLULAR LOCATION: [Assemblin]: Host nucleus. SUBCELLULAR LOCATION: [Assembly protein]: Host nucleus.
Protein: Y4QK_SINFN
Sequence: MGRLFGSLFHQTEELVMTPLRQRMSEDMQVRNFSLNTQLSYLRQVSLFARHFGKAPDLLGREDIRTYQVYLANEKKLAPNSIHIAIAALRFFFSVTLERDWVPAEVLPLPKKPQKLPIILSPDEVQHFLGCVLDLKHHAILTTCYAAGLRISEAVQLKPTDIDSQRMVVRVEQGKGQKDRYVMLSPKLLEILRDYWRMPRPKEWLFPGDRAGHPITRDAVGQACAKAHDLSRLSKPVTPHSLRHAFAVHLLEAGADVRTIQLLLGHRSLATTAHYLRIATNKVCATSSPFELLPRPAPTPPPAKPEYF
What is the function of this protein?
May function as an integrase.
What are the official names of this protein?
Putative integrase/recombinase y4qK.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family.
Protein: PTXBC_STAAW
Sequence: MTKEQQLAERIIAAVGGMDNIDSVMNCMTRVRIKVLDENKVDDQELRHIDGVMGVIHDERIQVVVGPGTVNKVANHMAELSGVKLGDPIPHHHNDSEKMDYKSYAADKAKANKEAHKAKQKNGKLNKVLKSIANIFIPLIPAFIGAGLIGGIAAVLSNLMVAGYISGAWITQLITVFNVIKDGMLAYLAIFTGINAAKEFGATPGLGGVIGGTTLLTGIAGKNILMNVFTGEPLQPGQGGIIGVIFAVWILSIVEKRLHKIVPNAIDIIVTPTIALLIVGLLTIFIFMPLAGFVSDSLVSVVNGIISIGGVFSGFIIGASFLPLVMLGLHHIFTPIHIEMINQSGATYLLPIAAMAGAGQVGAALALWVRCKRNTTLRNTLKGALPVGFLGIGEPLIYGVTLPLGRPFLTACIGGGIGGAVIGGIGHIGAKAIGPSGVSLLPLISDNMYLGYIAGLLAAYAGGFVCTYLFGTTKAMRQTDLLGD
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  This system is involved in the uptake and phosphorylation of MurNAc-GlcNAc, the principle peptidoglycan turnover product of S. aureus, yielding cytoplasmic MurNAc 6P-GlcNAc.
What are the official names of this protein?
PTS system MurNAc-GlcNAc-specific EIIBC component.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSMD3_DAUCA
Sequence: MTQDVEMKEVPAPAPSNSVTAATPSTLQHLKEIASLIESGAYAREVRRILRAVRLTIALRKKLNASVVNAFLNFSLVPGSEVHARLASYLPKEDEHDMEVDTAMSATTTLAKHSLPELEIYCYLLVLIFLIDQKKYSEAKACSSASIARVKNLNRRTVEVLASRLYFYYSLSYELTGDLAEIRGNLLALHRIATLRHDELGQETLLNLLLRNYLHYNLYDQAEKLRSKAPRFEAHSNQQFCRYLFYLGKIRTIQLEYTDAKESXLQAARKAPVAALGFRVQCNKWAVIVRLLLGEIPERTVFMQKGMEKALRPYFXLTNAVRIGDLELFRXVADKFASTFTADRTHNLIVRLRHNVIRTGLRNISISYSRISLVDVARKLRLDSPNPVADAESIVSKAIRDGAIDATIDHANGWMVSKETGDIYSTNEPQAAFNSRIAFCLNMHNEAVRALRFPANSHKDKESAEKRRERQQQEQELAKHIAEEDDDEF
What is the function of this protein?
Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
What are the official names of this protein?
Probable 26S proteasome non-ATPase regulatory subunit 3, 26S proteasome subunit S3, 26S proteasome regulatory subunit RPN3, Nuclear antigen 21D7.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S3 family.
What are the subcellular locations of this protein?
Nucleus.