PharMolix/UniProtQA huggingface dataset:
Protein: ATG2_NEUCR
Sequence: MSFFYRSFANSLLPKQLLRFILARLDLLDSQALDLDNLNFALGRNTVLEFRDVGLILSKLEALTNLPPTFKIQKAKVLLLRITIPVDIYNSPIIVEVEGVDTRIRVASKQEQDEQTAKNKKGTHKDGDEVVPTAADLAQSFLQTEIPTDEQRRLEKALAEEAQEALSESMSDSETDDDGSFATFGTGQGLSLPTFLTNFLQGILDRLQIRIHKVTFQLDMQVPVEPGLSTIELVTFQLALDEVIAEGVTAPGQQKDGSPAIVPREGKRHILLDNLRAFLITEANVFSSLLPTQSAQSLVKPQGPAPHDVPSTLRDMSGSMQSSVGGLDMSISPDQMEALDMLAQSQYEVRDSEDALNIPYESDTQYPEAEENVAGSSPLSTPRASMYQEHDTPMLQDHANSAIMQHQPELWSSYERGIRSEPSLHPPTSFQPQTMPSGAVSPAPSEPSSSASSVRSDDDTPSADTEDLAQSHLYSHEEAESMYMSAFSDAHSTLMPGAYMPGGWGAESEGGESASERDLSTTHPVAGEPQSSTPVVSELASPTPIPEQNPTAQGYEPQHEDTSTPRGITRMVKEIVSLDSISVYVPSTRKQVLAPVTNLAKSNPNLPGAFSVHQSFHSSTTDQSTLLTPENLKEDRQDYAIEIVLKPLTLRFDSSVGFLLAMVVTRLLEAFKGSSDEGAEVKPSSTESILPDIKVCLEQVTMQFLEELTGVADSAKRIYETQKPNFGSDVLLEASLTNLNAFTHQSGSQTEVNVSIEKFAFGYADEAIVSFTGEADLFQSTATVDMLSVGKDIAVKATITPDVTRVDVKTLPLYLKLDLQRLDETFSWFGGLSGFLNMGASEDSVAKAVQIPAKPPQKTRGVRFETPIDPMEKRSGSKIDVRINGVHVDVIGKDCRAVLNTSALKLVHREEAIAAVLKTIRLSGPYVRNSHARAPVVLELDSTRLDYILTPRTRDLERLLELITPSKVKFDEDEDEIMVDTLLRQRRKGGVLGLEVKNFKVRAGNLALLDCIPSLVDDLAKLGTVAKYLPEDDRPGLLTLGQVTNVDCEVDVGGRFGVVNARLTNLELAQITVPSLVAVAVGVVTVNRNENSPIEEELVSTSTAHAPGSSKAPVLMMRMIDDIEPVLKIKLFGLNVDYRVPTIMDVLGLIQEETTPEEFEANLAASVANLGGQATAALRRQDTPESPVVDKEFKPIKLDVAFRDCVVGLNPLGQDSKLAIVLADSHLEAIPGKDSTLDATATLKKACILLIDDVKTLQDVQINARGRAPAMSTPQALELCSKGFVSICEMSSAKAVVKVGKDENGESHVEVSVRDDLLVLETCADSTQTLISLANALTPPTPPSKEIKYRTSVLPVEDLFASITPDAFGRAEGEYDFDDDFAGAQGIECGNEDDDDYYGIGSTEHLEIQSEGYGVAEELFDATNSSLLGDIEVENTNDGMLVSTANLDVPPVSSQSESDLDIQENYFSSEPVKNTTLRWNSRKNLYDQSSDAQVFKSPLVICVRDVHVIWNLYDGYDWVRTREIITKAVQDVEAKAYERKARADRHTYEDEGDEESVVDDCLFNSIYIAVGPNGDPSNLRRAINQELQYQDTTTETESVATTAFTTSTVRASGHRQSRPRGKTLKLSRSKNHKITFELKGVNIDVVTFPPGNETINTIDVRIHDLDVFDHIRTSTWKKFAMYDIDAGERELSKHMVHLEVLNVKPVPDLPATELVVKVNILPLRLHVDQDALDFITRFFEFKDETQPIHQSSSDVPFIQRCEVGDVPVRLDFKPKRVDYAGLRSGHTTEFMNFVILEDSRLVLRHVILYGVSGFDKLGKKLNDIWTADVKSTQLPGVLAGVAPVRSLVNAGSGFKDLIEIPIREYKKDGRIFRSIGKGATAFAKTTGTEVVKLGAKLAIGTQYALQGAEGMLAKNPPNYNHAGPSSSSAGVPAGVDYEVWDEEDFGDHHTPKAISLYADQPLGIMQGMRGAYASLSRDIAIARDAIIAVPTEVMESSSAQGAAKAVLMQAPTILFRPAIGVSKAIGQTLLGATNALDPNHRKRIEAKYKKH
What is the function of this protein?
Lipid transfer protein required for autophagosome completion and peroxisome degradation.  Tethers the edge of the isolation membrane (IM) to the endoplasmic reticulum (ER) and mediates direct lipid transfer from ER to IM for IM expansion.  Atg-2 binds to the ER exit site (ERES), which is the membrane source for autophagosome formation, using basic residues in its N-terminal region (NR) and to the expanding edge of the IM through its C-terminal region.  The latter binding is assisted by an atg-18-PtdIns3P interaction.  Atg-2 then extracts phospholipids from the membrane source using its NR and transfers them to atg-9 to the IM through its predicted beta-sheet-rich structure for membrane expansion.
What are the official names of this protein?
Autophagy-related protein 2.
What is the protein family that this protein belongs to?
Belongs to the ATG2 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: MIC60_BLAGS
Sequence: MLRTSIASSRQVLSSPICPNPSVQWLHTSRARRVNAAASRRYYAVARKPNAGVRSSSTPNAAATPELSQKATNSTSTKPPGPNDPDVRSPASPSTGSTLHPETVSKPPQSPAVQGQTSPGSSVQPPEHEPSPPPPRPPPAPKTGLLRKLLYLFLTTGLAYAGGVWYSLRSDNFYDFFTEYIPYGEEAVLYLEERDFRSRFPSIARQINRRVSAPRDEGAQVMIPGRSGLSWKVAEEQQEASDVTKQGQHISATDANELTEETKVAEKAKEDVKSKPVAKKAEAAEPKSSPKVVEPHPAKAEENTSLEAPRQPVVPAAAAIEHLGLDNEDEPVVQDLVKVFNDIITVISADESASKFSVPIAKAKEELEKIGDRIVALKNDAQESAKEEIRNAQAALDKSAAELVRHINEVRAQDAAEFREEFESEREKISKSYQEKVTTELQRAHEVAEQRLRNELVEQAIELNRKFLADVKTLVENEREGRLSKLAELTANVAELERLTAGWSDVIDINLRTQQLQVAVDSVRTTLENSEVPRPFIRELAAVKELASNDEVVAAAIASISPTAYQRGIPSPAQLVDRFRRVASEVRKASLLPENAGITSHAASLVLSKVMLKKQGTPVGNDVESILTRTENLLEEGNFDEAAREMNSLQGWAKLLSKDWLADVRRVLEVKQALEVIETEARLRCLQVE
What is the function of this protein?
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.  Plays a role in keeping cristae membranes connected to the inner boundary membrane.  Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway (By similarity).
What are the official names of this protein?
MICOS complex subunit MIC60, Formation of crista junctions protein 1, Mitofilin.
What is the protein family that this protein belongs to?
Belongs to the MICOS complex subunit Mic60 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: KTHY_PARP8
Sequence: MARGKFITFEGIDGAGKTTHLGWFRDRLEQKVAPAGRSVVMTREPGGTKLGESLRDILLHEAMDLETEALLMFAARREHLAQVIEPALARGDWVLSDRFTDATFAYQGGGRGLPRDKLEALERWVQGGFQPDLTVLFDVPPDTASERRSAARAPDRFESESDAFFARTRAEYLRRAEEAPYRFAIIDSTRSIADIQKQLEDLIASL
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: TPM3_PIG
Sequence: MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAEFKCFELEEELKNVTNNLKFLEAQAEKYFQKKDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI
What is the function of this protein?
Binds to actin filaments in muscle and non-muscle cells.  Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction.  Smooth muscle contraction is regulated by interaction with caldesmon.  In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
What are the official names of this protein?
Tropomyosin alpha-3 chain, Gamma-tropomyosin, Tropomyosin-3.
What is the protein family that this protein belongs to?
Belongs to the tropomyosin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: WECG_YERPY
Sequence: MEPNTVIPKYNVRGFEIWGFRDMAQVLDHLLGSGPVKTGTLVAMNAEKLLKAEDDTALCELIKNAEYLYADGISMVRAIRRKYPQAELSRVAGADLWEALMQRAGQQGTPVFLVGGKPDVLAETEAKLRAQWNVNLVGSQDGYFTPEQREALFARIAASGAAIVTVAMGSPKQEIFMRDCRKFYPDALYMGVGGTYDVFTGHVKRAPKIWQNMGLEWLYRLLAQPSRIRRQLKLLKFVGYYYSGRL
What is the function of this protein?
Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis.
What are the official names of this protein?
UDP-N-acetyl-D-mannosaminuronic acid transferase, UDP-ManNAcA transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 26 family.
Protein: YC5G_SCHPO
Sequence: MSQKSHKEKLEKPAYKCMKQYICEKVSAHENDVVCITVQRFFQVVDGHMKEVRPMSNQIGLQSGPVVEKN
What are the official names of this protein?
Uncharacterized protein SPCC1259.16.
Protein: MYG_ZALCA
Sequence: MGLSDGEWQLVLNIWGKVEADLVGHGQEVLIRLFKGHPETLEKFDKFKHLKSEDEMKRSEDLKKHGKTVLTALGGILKKKGHHDAELKPLAQSHATKHKIPIKYLEFISEAIIHVLQSKHPGDFGADTHAAMKKALELFRNDIAAKYRELGFQG
What is the function of this protein?
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
What are the official names of this protein?
Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: NLK_CAEEL
Sequence: MVSWGRGKDAYYLYISREQEEDDDDSLSFYSSQKDTEDEFCGCLFPDPEIPGSSSSSGCSSSSTELYDLAAAHAALISRQQQILSQAIPIIPEHQLAAVAAHHQHHQQLHPSVQYQLVAAATHHNHHQPQAAQPHYSAVVPRSDVIQQPPHFALHHHLQNLVQQQQQQQAHHHHQQLVGEMALVSHTHPAAVGSTTCYEKNQQKQQQVQQIPTQPQVAHVSSNAILAAAQPFYPPPVQDSQPDRPIGYGAFGVVWSVTDPRSGKRVALKKMPNVFQNLASCKRVFREIKMLSSFRHDNVLSLLDILQPANPSFFQELYVLTELMQSDLHKIIVSPQALTPDHVKVFVYQILRGLKYLHTANILHRDIKPGNLLVNSNCILKICDFGLARTWDQRDRLNMTHEVVTQYYRAPELLMGARRYTGAVDIWSVGCIFAELLQRKILFQAAGPIEQLQMIIDLLGTPSQEAMKYACEGAKNHVLRAGLRAPDTQRLYKIASPDDKNHEAVDLLQKLLHFDPDKRISVEEALQHRYLEEGRLRFHSCMCSCCYTKPNMPSRLFAQDLDPRHESPFDPKWEKDMSRLSMFELREKMYQFVMDRPALYGVALCINPQSAAYKNFASSSVAQASELPPSPQAW
What is the function of this protein?
Has a role in the Wnt signaling pathway controlling the asymmetry of cell divisions during embryogenesis (PubMed:10380924).  Operates in the AB and EMS cell lineages influencing cell specification (PubMed:10391246).  Required for body wall muscle development, endoderm development, pop-1 asymmetry and T-cell division asymmetry (PubMed:10380924, PubMed:9384382).  Component of the beta-catenin-lit-1 complex which promotes the phosphorylation, down-regulation and subcellular relocation of pop-1 (PubMed:15066285, PubMed:10380924).  Regulates plp-1 nuclear localization in embryos (PubMed:19084000).  Plays a role in male tail tip morphogenesis (PubMed:21408209).
What are the official names of this protein?
Serine/threonine kinase NLK, Loss of intestine protein 1, Nemo-like kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Nucleus. Note=Located in the anterior cell cortex before and during asymmetric cell division. After division, located preferentially in the nucleus of the posterior daughter cell. Localizes to the nucleus in hyp9 and hyp10 cells prior to male tail tip morphogenesis (PubMed:21408209).
Protein: MURG_CALS4
Sequence: MRYLFAGGGTGGHIYPAVAIAKEILKNEQDAQILFVGTEKGLEKELVPREGFELVTIEVQGFKRKLSFDTLKTVYKAFTGFKQANKILKDFKPHVVIGTGGYVCGPVLMAAVIKRIPTLIHEQNAFPGLTNRLLSPFVDIVAVSFEDSVKYFKKAKKVVVTGNPIREELLRVKKEEGREKLGFSMSKPLVVSVGGSRGAEKINSTMVELLKIKDRKFQVLIITGSSNYDKVLEKVKKENVVLDDSVKIVPYSHEMQYVYAAADIMICRAGAITLSEITAVGVPSILIPSPYVANNHQEYNARLLERQGAFHVILEKDLDAKKLYEKIEYLLSEPSLLNEMREKAKSMSRTDASYKIYQLVKTIT
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: FENR2_ALKCK
Sequence: MQEQKDMFDLTIIGGGPAGLFAAFYAGMRKMKVKVIESMPQLGGQLSALYPDKYIYDVAGFPKVKAQDLVDQLTAQAQQFQPEIVLEEAVQTLEKQEDETFVLTTDANIHYTKAVLITAGAGAFAPRKLQVEKADFYEDKNIHYFIRDLSAFTGKRVVVIGGGDSAVDWALMLEPIAKEVTLVHRRDAFRAHEHSVDLLKKSSVRILTPYETAELHGDENGVTAVTFSEVKGDQTETIAVDDVIVNFGFVSTLGPIKEWGLEIRKNAIPVNTKMETNIPGVYAAGDVSTYDGKIKLIATGFGEAPTAVNNAKVYIDPTARAFPGHSTSLF
What are the official names of this protein?
Ferredoxin--NADP reductase 2, FNR 2, Fd-NADP(+) reductase 2.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: WALR_STAAR
Sequence: MARKVVVVDDEKPIADILEFNLKKEGYDVYCAYDGNDAVDLIYEEEPDIVLLDIMLPGRDGMEVCREVRKKYEMPIIMLTAKDSEIDKVLGLELGADDYVTKPFSTRELIARVKANLRRHYSQPAQDTGNVTNEITIKDIVIYPDAYSIKKRGEDIELTHREFELFHYLSKHMGQVMTREHLLQTVWGYDYFGDVRTVDVTIRRLREKIEDDPSHPEYIVTRRGVGYFLQQHE
What is the function of this protein?
Member of the two-component regulatory system WalK/WalR that regulates genes involved in cell wall metabolism, virulence regulation, biofilm production, oxidative stress resistance and antibiotic resistance via direct or indirect regulation of autolysins (By similarity).  Functions as a transcription regulator by direct binding to promoter regions (By similarity).
What are the official names of this protein?
Transcriptional regulatory protein WalR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZCHC4_MOUSE
Sequence: MAAPMDCLESLEGDGDAGRRASGVEVALPSNPTAPAPLCPHGPTLLFVKVNQGKEETRKFYACSACRDRKDCNFFQWEDEKLSEARLAAREIHNQKCQPPLSRAQCIERYLSFIQLPLAQRKFCQSCQQLLLPADWREHGTHQLSADISVAQLGRPSQLLYPLENKKTHAQYLFADRSCQFLAGLLATLGFSRVLCVGAPRLHEQIRLTASGERSGMRSLLLDIDFRYSQFYLEGSFCRYNMFNHHFFDGKAALEVCKEFLQEEEGKGVIMVTDPPFGGLVEPLAITFKKLIAMWKEGQSQDDSHKELPIFWIFPYFFESRICQFFPSFCMLDYQVDYDNHALYKHGKTGRKQSPVRIFTNVPPNKIILPSEEGYRFCSLCQRYVSRENQHCVHCNSCTSKDGRKWSHCFLCKKCVKPSWIHCNTCNRCALPDHSCLGPKDGCFICGALDHKRSNCPNIGTSWRANKLVEFFGFLEKRLLMSSFLGAIYRSTKLSEDSEFFRVLNRSSHHYV
What is the function of this protein?
rRNA N6-methyltransferase that specifically methylates the adenine in position 4220 of 28S rRNA.  N6-methylation of adenine(4220) in 28S rRNA is required for translation.
What are the official names of this protein?
rRNA N6-adenosine-methyltransferase ZCCHC4, Zinc finger CCHC domain-containing protein 4.
What is the protein family that this protein belongs to?
Belongs to the ZCCHC4 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Note=Accumulates in the nucleolus, where ribosome biogenesis takes place.
Protein: TATCY_BACSU
Sequence: MTRMKVNQMSLLEHIAELRKRLLIVALAFVVFFIAGFFLAKPIIVYLQETDEAKQLTLNAFNLTDPLYVFMQFAFIIGIVLTSPVILYQLWAFVSPGLYEKERKVTLSYIPVSILLFLAGLSFSYYILFPFVVDFMKRISQDLNVNQVIGINEYFHFLLQLTIPFGLLFQMPVILMFLTRLGIVTPMFLAKIRKYAYFTLLVIAALITPPELLSHMMVTVPLLILYEISILISKAAYRKAQKSSAADRDVSSGQ
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Required for YwbN secretion.
What are the official names of this protein?
Sec-independent protein translocase protein TatCy.
What is the protein family that this protein belongs to?
Belongs to the TatC family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TMM47_XENLA
Sequence: MASSASGMEEVRSSVLTPLKLVGLVCIFLALCLDIGAVLSPAWVTADNQYYLSLWESCKKSENRWICDSTLQSDWQIATLALLLGGAAIILIAFLVGLISICVGSRRRFYRPVAVMLFAAVVLQVCGLVLYPIKFIETVTLKIYHEFNWGYGLAWGATIFSFGGAILYCLNPKNYEDYY
What is the function of this protein?
Regulates cell junction organization in epithelial cells.  May play a role in the transition from adherens junction to tight junction assembly.
What are the official names of this protein?
Transmembrane protein 47, Transmembrane 4 superfamily member 10.
What is the protein family that this protein belongs to?
Belongs to the TMEM47 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell junction, adherens junction.
Protein: DXS_BACFR
Sequence: MKNEPTYSLLNAINYPKDLRQLSVDQLPEVCEELRQDIIKELSCNPGHFAASLGVVELTVALHYVYNTPYDRIVWDVGHQAYGHKILTGRREAFSTNRKLGGIRPFPSPEESEYDTFTCGHASNSISAALGMAVAAERKGEKDRHVVAVIGDGSMSGGLAFEGLNNASSTANNLLIILNDNDMAIDRSVGGMKQYLFNLTTSNRYNQLRFKTSRLLFKMGLLNEERRKALIRLGNSLKSLAAQQQNIFEGMNIRYFGPIDGHDVKNIARILHDIKDMQGPKILHLHTIKGKGFGPAEKQATIWHAPGKFDPVTGKRIVANTDGMPPLFQDVFGHTLVELAEKNKRIMGVTPAMPSGCSMNMLMDRMPDRAFDVGIAEGHAVTFSGGMAKDGLLPFCNIYSSFMQRAYDNIIHDVAIQKLNVVFCLDRAGLVGEDGPTHHGVFDMAYLRPIPNLTISSPMDEHELRRLMYTAQLPDKGPFAIRYPRGRGSLVDWECPLEEIPVGKGRKLKDGNDLAVITIGPIGKLAARAIERAEADTGISVAHYDLRFLKPLDEELLHEVGKKFRHIVTIEDGIIKGGMGCAILEFMADNGYYPEIRRIGVPDQFIEHGSVQQLYHLCGMDEEGIYKVITKNKLRMDAPVESCMATHS
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: CDN71_LITEW
Sequence: GLLDMVTGLLGNL
What is the function of this protein?
Caeridins show neither neuropeptide activity nor antibiotic activity.
What are the official names of this protein?
Caeridin-7.1.
What are the subcellular locations of this protein?
Secreted.
Protein: FTSB_CUPPJ
Sequence: MRLISLLLFVLLLAIQYPLWLGKGGWLRVWELNHQVQEQATRNQMLKLRNAKLEGEVKDLQDGTGAIEERARYELGMVKDGEVFVQFVAPAPKVSATPPLPPPPNSPAATGRH
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: EFCE2_BOVIN
Sequence: MACLGPSAQVPELPEKNCGYREVQYWDQRYQGAADSAPYEWFGDFSCFRDLLEPELRPLDRILVLGCGNSALSYEIFLGGFPDVTSVDYSSVVVAAMRARYAHVPTLRWETMDVRALGFPSGSFDVVLEKGTLDALLTGEQDPWTVSSEGVHTVDQVLNEAGFRKRTSRLLGLHTQLELVLAGVSLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAERKTQRFYLSCLQVERIEELGAQPLRDLIDKIGGWNVTGPWDQDNFMEVLKAVAGTYRATPFFTVYVSADSKSSNSNIIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGQPTSTREQMRQVLELEIQLANITVPQDQRRDEEKIYHKMSIAELQALAPSMDWLEFLSFLLSPLELGDSEPVVVYGTDYLQQVSELINRTEPSVLNNYLIWNLVQKTTSSLDHRFESAQEKLLETLYGTKKSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRAAFEEALGHLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEVSEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYTCNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACIEEQYSQYQVNGEKLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNSGQLCEVW
What is the function of this protein?
Converts big endothelin-1 to endothelin-1 (PubMed:7797512).  May also have methyltransferase activity (Probable).
What are the official names of this protein?
EEF1AKMT4-ECE2 readthrough transcript protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M13 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein. Cytoplasmic vesicle, secretory vesicle membrane.
Protein: ADDB_STAAE
Sequence: MTLHAYLGRAGTGKSTKMLTEIKQKMKADPLGDPIILIAPTQSTFQLEQAFVNDPELNGSLRTEVLHFERLSHRIFQEVGSYSEQKLSKAATEMMIYNIVQEQQKYLKLYQSQAKYYGFSEKLTEQIQDFKKYAVTPEHLEHFIADKNMQTRTKNKLEDIALIYREFEQRIQNEFITGEDSLQYFIDCMPKSEWLKRADIYIDGFHNFSTIEYLIIKGLIKYAKSVTIILTTDGNHDQFSLFRKPSEVLRHIEEIANELNISIERQYFNQLYRFNNQDLKHLEQEFDALQINRVACQGHINILESATMREEINEIARRIIVDIRDKQLRYQDIAILYRDESYAYLFDSILPLYNIPYNIDTKRSMTHHPVMEMIRSLIEVIQSNWQVNPMLRLLKTDVLTASYLKSAYLVDLLENFVLERGIYGKRWLDDELFNVEHFSKMGRKGHKLTEDERNTFEQVVKLKKDVIDKILHFEKQMSQAETVKDFATAFYESMEYFELPNQLMTERDELDLNGNHEKAEEIDQIWNGLIQILDDLVLVFGDEPMSMERFLEVFDIGLEQLEFVMIPQTLDQVSIGTMDLAKVDNKQHVYLVGMNDGTMPQPVTASSLITDEEKKYFEQQANVELSPTSDILQMDEAFVCYVAMTRAKGDVTFSYSLMGSSGDDKEISPFLNQIQSLFNQLEITNIPQYHEVNPLSLMQHAKQTKITLFEALRAWLYDEIVADSWLDAYQVIRDSDHLNQGLDYLMSALTFDNETVKLGETLSKDLYGKEINASVSRFEGYQQCPFKHYASHGLKLNERTKYELQNFDLGDIFHSVLKYISERINGDFKQLDLKKIRQLTNEALEEILPKVQFNLLNSSAYYRYLSRRIGAIVETTLSALKYQGTYSKFMPKHFETSFRRKPRTNDELIAQTLTTTQGIPINIRGQIDRIDTYTKNDTSFVNIIDYKSSEGSATLDLTKVYYGMQMQMMTYMDIVLQNKQRLGLTDIVKPGGLLYFHVHEPRIKFKSWSDIDEDKLEQDLIKKFKLSGLVNADQTVIDALDIRLEPKFTSDIVPVGLNKDGSLSKRGSQVADEATIYKFIQHNKENFIETASNIMDGHTEVAPLKYKQKLPCAFCSYQSVCHVDGMIDSKRYRTVDETINPIEAIQNININDEFGGEQ
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease AddB, DNA 3'-5' helicase AddB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 1 subfamily.
Protein: GLYA_META1
Sequence: MNKKVTLHDQDIADLINKESHRQEEHIELIASENYVSEDVMKAAGSSLTNKYGEGYPGKRYYGGCEFVDEIEKIAQERACKLFNAKYANVQPYSGSVANAAIYMALLNPGDSVLGLSLDSGGHLTHGYRISFSGIFYKSYTYTVNQDGVLDYDEILKIAQEVKPKMIICGYSAYSQIVDFAKFREIADAVGAYLFADIAHISGLVIANLHPSPMGYADVVATTTHKTLRGTRGAIILTNNEEIAKKIDRAVFPGNQGGPLFHQIAAKAVSFYEALQPEFIEYQRQIILNCKVFCQTFINKGVRVISGMTKNHLFTIDVKTSYNLTGKQAEQILSKMNITVNKNTIPFDTESPMVSSGIRLGVAAMTSRDFKEDEFIILANLIDKALREPNNETLHQVIKKEIAKLSHSFPIKRNYLDKK
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IML1_ASPFU
Sequence: MALRGPMKRSHLRQVSAPSVDSLSVPQSQSPEALYNDERSHQDVHATPDERTIRLSSGSLERRQCSLWVHDETFSREEILFNQAAFSDLNVNVGDVIEILPVRSPGDSIHSLKSDLGARSLRDSYLESGSAHLPDPMSKFKTPLQSRCLFVVKPLPQEIKARHPKLEISVTHSVANIFGFKNRTLVNISVVDRGQCSASHVDIAFRDQFLVRSDMWRLVMSELADKIIYKGQKIVFMGSIKATVKNIFIRGKKVLSGYFSPHTIPVFRSESAKYVLFIQMSREMWDFDSEGTGDILFSRVINGFLPELFKRWANSDAKHLVTIVLFTRVEYDSSALGGPLPLSSESLRCISSPNHAPTRDFYRVVVNDMASGHWTTILDELKKDFRTFLRDVSILKMDRPDTPTVDGVKVAPKNKPAIIAGRPSTALRGNILEAIHLASAHLAYDHIDRDLVHTGTSIIVITPGSGVFEVSYESLSSTSEALADRGIAIDLVCLSPMPLHSVPLFKYKAPVERSGSSSFGDFHSTGYSPEMRQSFSFASRTPHLSPKSTMQGSFPGMTRKEHLSARSDEWNYGIPHWLDISYWNPETYREARRIAKKDPNAPIPFTVTKQSKLFVPRVRMYEIQMMGVMESEQSDISIPYLLEGQGVSRPSNAGLGLGPSGLSSRASFRRNSSYKAQLSDSLRPEPFLQNITNPRDVMLAKAKKTPNQVIAWMDQYDEAVFQPFAKRRQQRKASRPKRPSEPEVQVSNAHERLSARSVLRLREHETNSNSGDRSYPTRTIPRVSETLSVPQGPAPSKASTSPKKPALKAPSAARTPRMSRTISFALLGFGATPPRAQASTEVNVEHARAQPTSGQKKPSVGFMDTRSVESFSGSDSASISTVIDTSLRPASPHPAPQTSAMTPTRPISIKVPPRQPSEDTEPVDRTVLPESYSTTSTAIPFTGDGRRDSRTKNGPSFELTVSGGSRESSIKSPQNKALAPWVRSINPCNTSRDVLRDTSWFGRWQHAYPRPPHVAVVKWKSLKSPAILPLTTEEFPTAQELGSDYLQTPYRVFPNDDPEGVEVPKTRGILLREMISLRLSHGFQIVIGKHVAEVSGQPALETLNVFDTRSLERDGATVFLSKGNTIHRLICVDGGEIEVTRFTHRTSSTLAAGKRDGFSLYTPAMRTILSTEYELKNIKLDPTAEDYNWNYADNYVAGHRDYLFNPAQQLQFWRVRYVLIPMPLQVNNRRHLQSFNEDNEEEIHLLGINQLTHIWQRHRYVPPEEKRFESSNEKKDQNPLNIMYQTRNPSEVVAAELDRILLSDPGLDNSPAQLLPESELLERSSISLSSLAQIIQGEKGVRMMDRRWHWRLHYNCFIGFEFTTWLLQNFRDIDSREEAVQFGNELMKHGLFQHVEKRHNFRDGNYFYQISSEYRVARPESRGSWFPQKKPDKQVPSTGASENPRDSAVNGHSRSESVETPATPSKSKNKATIMLSKMMKYDVDPRKRSNRPEVIDLHYDRLHNPDNCFHIELSWMNTTPKLIEDAVLSWAATAEKFGLKLVQVPIAEGCAISRTQPFRKPYRVSLAVPPPPGPVPTVFNTATFSQLGSSDRHYYHKALLRKFDFVLDFEARSAFPADVEVSYSWGTPDYQYPQYIHRSGSLLVQITDEGDFLFLANRLVSTRLAAATREGSRYERMDRPEHLRARASTHDPLDRISPRLSPLVRPLHDIGSPISPQGQPSIDLAQLYRAPEHILNSFEEFCNDAARLEQFYSVSHARPASTKVGPAPTTVMDSSIPTLELPASVVSHHIQSPALTTRASVDGSMPSVDAMTRARNDSLSYKGSPKSGSLRPLNIN
What are the official names of this protein?
Vacuolar membrane-associated protein iml1.
What is the protein family that this protein belongs to?
Belongs to the IML1 family.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein.
Protein: SYP_META3
Sequence: MENFSEWYHNILETAGIYDLRYPLKGCGVYLPYGFKIRRYAFEAIRDMLDESNHDEALFPMLIPEDLLAKEGEHIKGFEEEVYWVTHGGTTPLDVKLALRPTSETPIYHMMKLWIKVHTDLPIKIYQIVNSFRYETKHTRPLIRLREIMTFKEAHTAHSTSEEAEAQVQTALNIYKTFFDRMGVPTIVSQRPEWDKFPGADYTMAFDTIFPDGKTMQIGTVHNLGQHFAKTFELEFETPEGGKDYAYQTCYGISDRIIASIIALHGDEKGLILPPEVAPHQIIIIPLLFKGKEEIAMNKAKEIYKSLKNTYRVKLDDRDIRPGKKFNDWELKGAPIRIELGPRDIENNKLTIYRRDTGEKFQIDEDNLLNELNTLIDSIENTIKEKAEQKVKSFITILDNHDVNNIKETLSTKKGVVLVPYDENIYTEEFEEEIDASVLGTTEYDGKKYISIAKTY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.