PharMolix/UniProtQA huggingface dataset:
Protein: LRGB_STAAM
Sequence: MINHLALNTPYFGILLSVIPFFLATILFEKTNRFFLFAPLFVSMVFGVAFLYLTGIPYKTYKIGGDIIYFFLEPATICFAIPLYKKREVLVKHWHRIIGGIGIGTVVALLIILTFAKLAQFANDVILSMLPQAATTAIALPVSAGIGGIKELTSLAVILNGVIIYALGNKFLKLFRITNPIARGLALGTSGHTLGVAPAKELGPVEESMASIALVLVGVVVVAVVPVFVAIFF
What is the function of this protein?
Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and/or CidB.  The LrgAB and CidAB proteins may affect the proton motive force of the membrane.  May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses.
What are the official names of this protein?
Antiholin-like protein LrgB.
What is the protein family that this protein belongs to?
Belongs to the CidB/LrgB family. LrgB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RFAL_SALTY
Sequence: MLTTSLTLNKEKWKPIWNKALVFLFVATYFLDGITRYKHLIIILMVITAIYQVSRSPKSFPPLFKNSVFYSVAVLSLILVYSILISPDMKESFKEFENTVLEGFLLYTLLIPVLLKDETKETVAKIVLFSFLTSLGLRCLAESILYIEDYNKGIMPFISYAHRHMSDSMVFLFPALLNIWLFRKNAIKLVFLVLSAIYLFFILGTLSRGAWLAVLIVGVLWAILNRQWKLIGVGAILLAIIGALVITQHNNKPDPEHLLYKLQQTDSSYRYTNGTQGTAWILIQENPIKGYGYGNDVYDGVYNKRVVDYPTWTFKESIGPHNTILYIWFSAGILGLASLVYLYGAIIRETASSTLRKVEISPYNAHLLLFLSFVGFYIVRGNFEQVDIAQIGIITGFLLALRNR
What is the function of this protein?
Adds the O-antigen on the glucose(II) group of LPS.
What are the official names of this protein?
O-antigen ligase.
What is the protein family that this protein belongs to?
Belongs to the O-antigen polymerase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATP25_YEAS7
Sequence: MNKFCLLPFHGKRIGVANIPFTILLKKGPYFLHSHITAVYYSTKGKNDSHEQSRVSKKSTFTPLETPWYLRIVDNEKELMEGKKNNHHTMNKELEIPKTSPNSLRKIADLLTGKLGLDDFLVFDLRKKSPNSVSAVNKLGDFMVICTARSTKHCHKSFLELNKFLKHEFCSSAYVEGNFNERQESRRKRRLARKSNLSKLLGRSSECSAKDLNSEAWYMIDCRVDGIFVNILTQRRRNELNLEELYAPENEKSKFQNIDSGNVPTISGVNEISSNNNILLGLRRLAQQRRRYSTINPNGLSNLRYFLQKEDFKGANKIIQSSSGTETHNIRTLEHVKNTLKDLVGQEKKVDVVQWKSLFDEHSTFLTINQSAAYWPLRLEYAILLNKADPQFYSDRVFLKDYLLLKKSLGQELIREDLIALLEMVLKTQHSSHSYFNLVKQNRVIIRALNLFKGLQTEDNGSVVYDEEVISLLLNSMVADERVKLRSLYETIDHIFQTFGDKLTSGMIVSILQNLAKIKDWNKLLQVWEAITPTEGEGQDKRPWNEFINVINQSGDSHVISKIVNNGHLLWIRRLNVNVTPELCNSIKALLKTAGMENSTLEEFLVRGKNNQ
What is the function of this protein?
mRNA stabilization factor specific for the 0. 95 kb OLI1 mRNA.  Also involved in OLI1 ring formation (By similarity).
What are the official names of this protein?
ATPase synthesis protein 25, mitochondrial, OLI1 mRNA stabilization factor.
What is the protein family that this protein belongs to?
Belongs to the ATP25 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: GT101_ORYSJ
Sequence: MGTRRRSARARARPPLAMPLAVLLLFACSSGVAAAAAQGIERIKDDPVGKLKVYVYELPPKYNKNIVAKDSRCLSHMFATEIFMHRFLLSSAIRTSNPDEADWFYTPVYTTCDLTPWGHPLTTKSPRMMRSAIKFISKYWPYWNRTEGADHFFVVPHDFAACFYFQEAKAIERGILPVLRRATLVQTFGQKNHACLKDGSITVPPYTPAHKIRAHLVPPETPRSIFVYFRGLFYDTSNDPEGGYYARGARASVWENFKNNPMFDISTDHPQTYYEDMQRAVFCLCPLGWAPWSPRLVEAVVFGCIPVIIADDIVLPFSDAIPWEEIAVFVAEDDVPQLDTILTSIPTEVILRKQAMLAEPSMKQTMLFPQPAEPGDGFHQVMNALARKLPHGRDVFLKPGQKVLNWTEGTREDLKPW
What is the function of this protein?
Involved in the synthesis of glucuronoxylan hemicellulose in secondary cell walls.
What are the official names of this protein?
Probable glucuronosyltransferase GUT1, Glucuronoxylan glucuronosyltransferase 1, OsGUT1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 47 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: MNME_LATSS
Sequence: MPTTVTEFDTITAISTPPGEGAISIVRLSGDDSLAIIKRVYRGKDLDKVASHTINYGHIIDPKTDAVVDEVMVSVMRAPKTFTREDVIEINCHGGIVATNRILQLLMSYGARMAEPGEFTKRAFLNGRIDLTQAESVMDLIRAKTDRAMQVAVDQLDGSLTHLIKNLRQEILEVLAQVEVNIDYPEYDTDEMTTRILLEKAELVKGRIGELLQTAQQGKVLREGLATAIVGRPNVGKSSLLNHLLHEDKAIVTDVAGTTRDVLEEYVNVRGVPLKLVDTAGIHDTEDKVEKIGVERSRAAITKADLILLVLNQSEPLTIEDRELITATTDKKRIIILNKTDLPNQLDLDELQTLVRADEVIQTSILTSEGVTDLEAQIAKLFFGGIENSQSTVMITNARQIGLLNQAQQSLDEVISGIAAGMPVDLVQIDMTNCWDKLGEITGDSAPDELITELFSQFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYFP2_MOUSE
Sequence: MTTHVTLEDALSNVDLLEELPLPDQQPCIEPPPSSIMYQANFDTNFEDRNAFVTGIARYIEQATVHSSMNEMLEEGHDYAVMLYTWRSCSRAIPQVKCNEQPNRVEIYEKTVEVLEPEVTKLMKFMYFQRKAIERFCSEVKRLCHAERRKDFVSEAYLLTLGKFINMFAVLDELKNMKCSVKNDHSAYKRAAQFLRKMADPQSIQESQNLSMFLANHNRITQCLHQQLEVIPGYEELLADIVNICVDYYENKMYLTPSEKHMLLKVMGFGLYLMDGNVSNIYKLDAKKRINLSKIDKFFKQLQVVPLFGDMQIELARYIKTSAHYEENKSKWTCTQSSISPQYNICEQMVQIRDDHIRFISELARYSNSEVVTGSGLDSQKSDEEYRELFDLALRGLQLLSKWSAHVMEVYSWKLVHPTDKFCNKDCPGTAEEYERATRYNYTSEEKFAFVEVIAMIKGLQVLMGRMESVFNQAIRNTIYAALQDFAQVTLREPLRQAVRKKKNVLISVLQAIRKTICDWEGGREPPNDPCLRGEKDPKGGFDIKVPRRAVGPSSTQLYMVRTMLESLIADKSGSKKTLRSSLDGPIVLAIEDFHKQSFFFTHLLNISEALQQCCDLSQLWFREFFLELTMGRRIQFPIEMSMPWILTDHILETKEPSMMEYVLYPLDLYNDSAYYALTKFKKQFLYDEIEAEVNLCFDQFVYKLADQIFAYYKAMAGSVLLDKRFRAECKNYGVIIPYPPSNRYETLLKQRHVQLLGRSIDLNRLITQRISAAMYKSLDQAISRFESEDLTSIVELEWLLEINRLTHRLLCKHMTLDSFDAMFREANHNVSAPYGRITLHVFWELNFDFLPNYCYNGSTNRFVRTAIPFTQEPQRDKPANVQPYYLYGSKPLNIAYSHIYSSYRNFVGPPHFKTICRLLGYQGIAVVMEELLKIVKSLLQGTILQYVKTLIEVMPKICRLPRHEYGSPGILEFFHHQLKDIIEYAELKTDVFQSLREVGNAILFCLLIEQALSQEEVCDLLHAAPFQNILPRVYIKEGERLEVRMKRLEAKYAPLHLVPLIERLGTPQQIAIAREGDLLTKERLCCGLSMFEVILTRIRSYLQDPIWRGPPPTNGVMHVDECVEFHRLWSAMQFVYCIPVGTNEFTAEQCFGDGLNWAGCSIIVLLGQQRRFDLFDFCYHLLKVQRQDGKDEIIKNVPLKKMADRIRKYQILNNEVFAILNKYMKSVETDSSTVEHVRCFQPPIHQSLATTC
What is the function of this protein?
Part of the WAVE1 complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex (By similarity).  Involved in T-cell adhesion and p53-dependent induction of apoptosis (By similarity).  Does not bind RNA.  As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (PubMed:27605705).
What are the official names of this protein?
Cytoplasmic FMR1-interacting protein 2, p53-inducible protein 121.
What is the protein family that this protein belongs to?
Belongs to the CYFIP family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, perinuclear region. Synapse, synaptosome. Note=Highly expressed in the perinuclear region and enriched in synaptosomes (PubMed:11438699).
Protein: SYC_MESFL
Sequence: MKLFDTLTQEQKNINKEVINIYSCGPTIYDYIHIGNARPIILMDTLIRFLESEGIKVNFLQNITDIDDKIIEKAIQENKTEKEITDKYLSAFLQNLKDLKIRMPDKLIPISEKISEMNLFIDDLVKLEAAYNVDGDVYFDIQKFSDEYGKLSNKKINDLISGNRVEIEDKKNNPLDFSVWKKTEKGITFDSNFGKGRPGWHTECALLIDEYFKGETIDIHSGGIDLQFPHHENERIQFIAKHGKEISDIWVHNGHLTINGEKMSKSLGNTMTLTNFLANYNSDILRWIFLTTYYKQPLNINDDLIEQANKFIQKINNLSKKIKQLLIENKFVKTNQFDEEIIKQFKIHMKNDLNTSRVLTLLEDTLKDINKLSTLKEFDDLFLKINSLNYILKTLGLSININTFVSDEEQNLFLLWKKIVSEKDFEKADEIRKVLISKGIL
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTU_SALAR
Sequence: MPESKYRQQTIRAPRGATLTAKSWLTEAPLRMLMNNLDPDVAENPHELVVYGGIGRAARNWECYDAIVDALTRLEADETLLIQSGKPVGVFKTHDNAPRVLIANSNLVPHWATWEHFNELDAKGLAMYGQMTAGSWIYIGSQGIVQGTYETFVEAGRQHYNGTLAGRWVLTAGLGGMGGAQPLAATLAGACSLTIECQQSRIDFRLRTRYVDEQAATLDDALARIAHYTRAGKAVSVALCANAADILPELVNRGVRPDLVTDQTSAHDPLHGYLPTGWRWEEYQEKALSDPQGTMQAAKRSMAAHVQAMLAFSKMGVPTFDYGNNIRQMAKEMGVENAFDFPGFVPAYIRPLFCRGIGPFRWVALSGDPQDIYKTDAKVKEIVAEDKHLHHWLDMARERIHFQGLPARICWVGLEWRQKLGLAFNEMVRCGEVSAPIVIGRDHLDSGSVASPNRETEAMRDGSDAVSDWPLLNALLNTASGATWVSLHHGGGVGMGFSQHAGMVIVCDGTDEAAARIRRVLHNDPATGVMRHADAGYDLAVECAVEQGLHLPMVAATQRKR
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAHH_BRUA2
Sequence: MTASQDFVVKDISLADWGRKELDIAETEMPGLMAAREEFGKSQPLKGARISGSLHMTIQTAVLIETLKVLGAEVRWASCNIFSTQDHAAAAIAATGTPVFAVKGETLEEYWTYTDQIFQWPDGEPSNMILDDGGDATMYILIGARAEAGEDVLSNPQSEEEEVLFAQIKKRMAATPGFFTKQRAAIKGVTEETTTGVNRLYQLQKKGLLPFPAINVNDSVTKSKFDNKYGCKESLVDGIRRGTDVMMAGKVAVVCGYGDVGKGSAQSLAGAGARVKVTEVDPICALQAAMDGFEVVTLDDAASTADIVVTTTGNKDVITIDHMRKMKDMCIVGNIGHFDNEIQVAALRNLKWTNVKPQVDLIEFPDGKRLILLSEGRLLNLGNATGHPSFVMSASFTNQVLGQIELFTRTDAYKNEVYVLPKHLDEKVARLHLDKLGAKLTVLSEEQAAYIGVTPQGPFKSEHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADK_EDWI9
Sequence: MNKRFESIGLVGHPRHPAALATHEMLFHWLTGKGYPVIVERQIARDLKLQHALTGTLADIGQQADLAVVVGGDGNMLGAARILARYDVDVIGVNRGNLGFLTDLDPDNAKQQLSCVLEGEYSRERRFLLEVKVCRDGQMHRRSTAINEVVLHPGKVAHMIEFEVYINDTFAFSQRSDGLIISTPTGSTAYSLSAGGPILAPTLDAIALVPMFPHTLSARPLVIDSNSKIHLRFSHFSNELEISCDSQIALPIQQGEEVIVQRSPFYLSLIHPKDYSYFNTLSSKLGWSKKLF
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YAGA_ECOLI
Sequence: MESLMPWDARDTMSLRTEFVLFASQDGANIRSLCRRFGISPATGYKWLQRWAQEGAAGLQDRPRIPHHSPNRSSDDITALLRMAHDRHERWGARKIKRWLEDQGHTMPAFSTVHNLMARHGLLPGASPGIPATGRFEHDAPNRLWQMDFKGHFPFGGGRCHPLTLLDDHSRFSLCLAHCTDERRETVQQQLVSVFERYGLPDRMTMDNGSPWGDTTGTWTALELWLMRLGIRVGHSRPYHPQTQGKLERFHRSLKAEVLQGKWFADSGELQRAFDHWRTVYNLERPHEALDMAVPGSRYQPSARQYSGNTTPPEYDEGVMVRKVDISGKLSVKGVSLSAGKAFRGERVGLKEMQEDGSYEVWWYSTKVGVIDLKKKSITMGKGC
What are the official names of this protein?
Uncharacterized protein YagA.
Protein: RSMH_ANAMF
Sequence: MVHKPVLLNEVVEALSPKDGSVYVDATFGGGGYSRRILETAQCVVYAIDQDVVVKKYFDELLQSFPGRLNLAISRFSKLREVVLSFGVDKVDGVVFDLGTSAMQLADASRGFSFMNSGSLDMRMCSSALRDAAMFVNTVPEKEMADVIYQYGGERYSRRVARAIIDARRKCRINNTGDLATIIRSAVPRSRVHPIDPATRTFQAIRIWVNNELEELQAGLEAAAEVLKIGGKILVTSFHSLEDRVVKHKFRSLCDMGFSLINKKAIMPTDEEVKNNPRSRSGKLRAIARVE
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_CERS5
Sequence: MLDQTNYTPRLKSLYASNVRAALKEQFSYKNDMQIPRLDKIVLNMGVGEAVKDTKKVKTAAEELSMIAGQKAVITHAKKSIAGFRVRELMPLGCKVTLRGDRMYEFLDRLITIALPRVRDFRGVKGNSFDGRGNYAMGLKEQFVFPEINFDKVDEVLGMDIIICTTAKTDAEAKALLKQFNMPFVS
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: RUVC_HAEIN
Sequence: MSIILGIDPGSRVTGYGVIRQTGKHLEYLGSGAIRTQVEDLPTRLKRIYAGVTEIITQFQPNMFAIEQVFMAKNADSALKLGQARGTAIVAAVNNDLPVFEYAARLVKQTVVGIGSADKVQVQEMVTRILKLSDKPQADAADALAIAITHAHSIQHSLHIANSVKMTETQEKMTALLKTRYSRGRFRLKI
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: SMIM1_HUMAN
Sequence: MQPQESHVHYSRWEDGSRDGVSLGAVSSTEEASRCRRISQRLCTGKLGIAMKVLGGVALFWIIFILGYLTGYYVHKCK
What is the function of this protein?
Regulator of red blood cell formation.
What are the official names of this protein?
Small integral membrane protein 1, Vel blood group antigen.
What is the protein family that this protein belongs to?
Belongs to the SMIM1 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: IXTPA_XANCP
Sequence: MKHLVLASGNAGKLEELRAMLADLPLQIVAQGELGVDDVPETGLTFVENALIKARHASTVTGLPALADDSGLIVDALGGAPGLYSARYAGSPTDANANNAKLLEAMREIPAERRSARFYAVIVLLRHPEDPQPLIAEGSWEGVITTAPRGTGGFGYNPVFLDPVHGLTAAEMDTALKNRLSHRAVALATLQHKLHALSL
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: TRHO_EHRRG
Sequence: MGYVVSTFYRFVHLSNYYDIRPVLKEFCVQNNIKGTIILAEQGINATIAGSQNSLDKFFSFLDLDSRLCNLQYHKSFSRCNPFSKMKVKLRKELVCLGIEDFDNSVSGEYIDPENWDNFISRSDVYTIDTRNSYEINFGKFKNSINPETNCFRDFPDWAISWAKNKIDDDPIIAMYCTGGIRCEKSTAFMKDLGFSKVYHLKGGILEYFKSTGNINNLWEGYCFTFDDRIIVDDKLVPGDVKCILCGAHVMLEDMKSISRGHVLCFSCKDHV
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: YIDC_MYCPN
Sequence: MPLNLNKKHKELKTTFNPFWSAAVVNEKNGLKNLKKAWGIIFKVLKVAIFIFLTIVGLWGCTQTLAQPWTGTNQLLGSGLEIGYNFGTTGDYRYDLQSNNVGPYFTFSDYTLAYGPFYGWFVWPASQIVLPIMYATRVPLGSGPELGFNMILSLIVLLFLVRLITIVITLNSTLALEKMNEVQGKLAEINAKYKGALDLQSKRNRQMEIMSLYKKHNIKSSASFVQVFVTLPIFLIIYRIVTTLRPIKAIILFNFWDLSKVPLTEIFSNFTSTGWTFIIFLIIVLPVQFISQKLPQIWASKRNENAKAHSQKSIEQLNKTKRMQLIFYFVFAVITAFSAAGVGVYWFLNALFTLLQSYLTHLFIVKRRTRRRLTYSKLEQMLERE
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins (By similarity).
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CWP11_SOLLC
Sequence: EQXGRQRQGG
What are the official names of this protein?
35 kDa cell wall protein.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: UFL1_DROER
Sequence: MGSDWDEIKRLAADFQKAQLTSTLQKLSERNCVEIVTLLLEKQMLEVVFTNDGKEYITPDHLEREIQDELYVNGGRANLVEVSKTLNVDLSRIEVLAERIAAENPSVHLVLGQLIDEDYISHIAQEINEKLVLRGEISISELASQFDLPSDFLQHDVVEKHLGKIIKGRQDAANPRVFFTQAYIQRCKAKIRGALAAITRPINVAVILQQIGVQEKIFHSLLDEIAPAGQVTSKLANSQYVPHIYAKTQADWVNSFYKQNSFLEYDAIQKLGISDAKSYIRKQFPNEEFLFLKRVALGARLVELTVVTALNECSATKQYLDLTTILPSNLSEEDIEEVFSTIMAQKHSNPSNFVYLDSIVFSQPYLAQLVQPCQALAESQAKAAIDGGVYQQYIVEKTLAQKGNASTQELEDDGKVDKRDERRKKASSGKAGGGAQGRETKTKSTKKHQRGKAAAHNDSDDEDDVQQGSRGGGGVNKKAVKPLELVKTADIVKLITASLEEEGLEHLSKPIAALYTNQFNQTALARAQELFEATPQTNRRQTHAAIQDRINTLLIDIRLYEKGLKLFPQDTQTQLVKYLLKSLGNDICNELSLYVAGECNLTVKNTNLNVDQRNKLAQECEAQYRAALLEQNKALNKSIDEFELATETVLKACSMIIKKVDKKKDRLLIADHKKKLQKQLLECQDPALLLHLAALILFTAISGSILHASGKFVSAILQHIRGSLNEEQNALLLRYHDLVLQVLQATPDSSESKMANEHLQAMQAQVVELAQNFSRASVSKAD
What is the function of this protein?
E3 UFM1-protein ligase that mediates ufmylation of target proteins.
What are the official names of this protein?
E3 UFM1-protein ligase 1 homolog, E3 UFM1-protein transferase 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the UFL1 family.
Protein: ATSA_KLEAE
Sequence: MNKKAMAAAVSMILAGGAHAAQQERPNVIVIIADDMGYSDISPFGGEIPTPNLQAMAEQGMRMSQYYTSPMSAPARSMLLTGNSNQQAGMGGMWWYDSTIGKEGYELRLTDRVTTMAERFKDAGYNTLMAGKWHLGFVPGATPKDRGFNHAFAFMGGGTSHFNDAIPLGTVEAFHTYYTRDGERVSLPDDFYSSEAYARQMNSWIKATPKEQPVFAWLAFTAPHDPLQAPDEWIKRFKGQYEQGYAEVYRQRIARLKALGIIHDDTPLPHLELDKEWEALTPEQQKYTAKVMQVYAAMIANMDAQIGTLMETLKQTGRDKNTLLVFLTDNGANPAQGFYYESTPEFWKQFDNSYDNVGRKGSFVSYGPHWANVSNAPYANYHKTTSAQGGINTDFMISGPGITRHGKIDASTMAVYDVAPTLYEFAGIDPNKSLAKKPVLPMIGVSLSAISPAKYRSRRAELRG
What is the function of this protein?
Plays an important role in the mineralization of sulfates.
What are the official names of this protein?
Arylsulfatase, AS, Aryl-sulfate sulphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the sulfatase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: H2A1_YEAST
Sequence: MSGGKGGKAGSAAKASQSRSAKAGLTFPVGRVHRLLRRGNYAQRIGSGAPVYLTAVLEYLAAEILELAGNAARDNKKTRIIPRHLQLAIRNDDELNKLLGNVTIAQGGVLPNIHQNLLPKKSAKATKASQEL
What is the function of this protein?
Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A.1.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: PYRI_SERMA
Sequence: MTHDNKLQVEAIKCGTVIDHIPAQIGFKLLTLFKLTATDQRITIGLNLPSNELGRKDLIKIENTFLTEQQANQLAMYAPKATVNRIDNYEVVRKLTLSLPDHIDGVLTCPNGNCISRSEPVRSSFSVKSRGGEVHLKCRYCEKEFEHQVVLQAD
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: G6PI_LACAC
Sequence: MSLIKFDSSKLTPFIHENELSEMQAMVNAANEELRDGTGAGSDFRGWLNLPVDYDKEEFDRIKKAAKKIQSDSDVLICIGIGGSYLGAQAAIEFLNSNFYGKEDNGMPTVVFCGNSLSGSYLYDLIEWVGDKDFSINVISKSGTTTEPSVAFRIFKDKLIKKYGKEEAAKRIYATTDRQKGALKTEADAEGYEEFVVPDDIGGRYSVLTAVGLLPIAASGADIDELMKGAADARADYTDTDLSKATPYQYAAIRNILYRKGYTTEIVENYEPSLRMFGEWCKQLMGESEGKDQKGIWPSSANFTTDLHSLGQYIQEGLRNLFETVIRVENPRHDVKIPGDEKNLDQLNFLEGKSLNYVNDRAYEGVVLAHTDGGVPVMTINIPDQTAHTLGYMIYFFELAIAISGYLNGINPFNQPGVEAYKRNMFGLLNKPGYENLHDDLAKRL
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAD4_ASHGO
Sequence: MENPHEKVQVGILARIVGNVERLNQSVATLNQELERINTRNRNLELMGQMCEHYGRATAFNLKTTGNRQGPV
What is the function of this protein?
Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation.  The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore (By similarity).
What are the official names of this protein?
DASH complex subunit DAD4, Outer kinetochore protein DAD4.
What is the protein family that this protein belongs to?
Belongs to the DASH complex DAD4 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Associates with the mitotic spindle and the kinetochore.
Protein: AQP2_TALEU
Sequence: SIAFSRAVFAEFLATLIFVFFGLGSALNWQQSLPSVLQIAMAFGLAIGTLVQALGHISGAHINPAVTVACLVGCHVSFLRAAFYVAAQLLGAVAGAALLHEVTPSDVRG
What is the function of this protein?
Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
What are the official names of this protein?
Aquaporin-2, AQP-2, ADH water channel, Aquaporin-CD, AQP-CD, Collecting duct water channel protein, WCH-CD, Water channel protein for renal collecting duct.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Note=Shuttles from vesicles to the apical membrane. Vasopressin-regulated phosphorylation is required for translocation to the apical cell membrane. PLEKHA8/FAPP2 is required to transport AQP2 from the TGN to sites where AQP2 is phosphorylated.