PharMolix/UniProtQA huggingface dataset:
Protein: GTPB1_XENLA
Sequence: MASLASSQTEPNTSESPVPASMFSPEPDGEDSDCSLDGEPLRNGEADIDVTSKFVLVSPSAEQYDSLLHQLRDRMDEGRGETIYVIGQGSDGTEYGLNEADMEASVATVTSMAEQIVADMILLREHQEAGGKVQDYLVRKSVGDNDFLEVRVAVVGNVDAGKSTLLGVLTHGELDNGRGFARQKLFRHKHEIESGRTSSVGNDILGFDNHGQVVNKPDNHGGSLEWTKICEKSSKIITFIDLAGHEKYLKTTVFGMTGHLPDFCMLMVGSNAGIVGMTKEHLGLALALNVPVFVVVTKIDMCPANILQETLKLLQRLLKSPGCRKIPVLVQNKDDVIVTASNFSSERMCPIFQISNVTGENLDLLKMFLNLLSPRSSSREEEPAEFQIDDTYSVPGVGTVVSGTTLRGLIKLNDLLLLGPDPLGNFTSIAVKSIHRKRMPVKEVRGGQTASFALKKIKRSTIRKGMVMVSPRLNPQASWEFEAEILVLHHPTTISPRYQAMVHCGSIRQTATILTMSRDCLRTGDKAIVHFRFIKTPEYLHIDQRLVFREGRTKAVGTITKLLQSTNNLPMNSKPPQQVKMQSTKKSLHGKKDEQSPAAAVTEEASPSAAAIGVTAGAGAMQAQPKTGGGGRRRGGQRHKVKAQGACTASTGGC
What is the function of this protein?
Promotes degradation of target mRNA species.  Plays a role in the regulation of circadian mRNA stability.  Binds GTP and has GTPase activity (By similarity).
What are the official names of this protein?
GTP-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. GTPBP1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y233_ARCFU
Sequence: MMNLSPPFKSPSGSSRAGRRNQLCCRRFRVPGKPLRNSTLKFFLLIRHTGCSRSRSFLEKAIVLSCPSAGLRSKGFSHEECR
What are the official names of this protein?
Uncharacterized protein AF_0233.
Protein: CLOT_PENPU
Sequence: LQPGLEYQYRYSARV
What is the function of this protein?
Forms stable clots in the presence of calcium.
What are the official names of this protein?
Hemolymph clottable protein, Clotting protein, CP.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: LNT_SALTI
Sequence: MAFASLIERQRIRLLLALLFGACGTLAFSPYDVWPAAIVSLIGLQALTFNRRPLQSAAIGYCWGLGLFGSGINWVYVSIAQFGGMPGPVNVFLVVLLAAYLSLYTGLFAGILSRLWPKTNWLRVAIAAPAIWQITEFLRGWVLTGFPWLQFGYSQVDGPLKGLAPVMGVEAINFLLMMVSGLLALALATRNWRPLAVAVILFALPFPLRYIQWFTLEPTKATQVSLVQGDIPQSLKWDENQLLNTLNIYLNETRPELGKSQIIIWPESAIPDLEINQQPFLRSLDEMLREKNSTLITGIVDARLNKQNRYDTYNTIITLGKDNPYSYDSPNRYNKNHLVPFGEFVPLESILRPLAPFFDLPMSSFSRGPYIQPQLHAHDYKLTAAICYEIILGEQVRDNFRPDTDYLLTISNDAWFGKSIGPWQHFQMARMRSLELARPLLRSTNNGITAVIGPQGEIQAMIPQFTRQVLTTKVTPTTGLTPYARTGDWTVWLITVLFGFGALVMSLRQRRK
What is the function of this protein?
Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
What are the official names of this protein?
Apolipoprotein N-acyltransferase, ALP N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MEF2B_MOUSE
Sequence: MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCDIALIIFNSAQRLFQYASSDMDRVLLKYTEYSEPHESRTNADILQTLKRRGVGLDGPELDMEEGPEGPGEKLLRTLGGDRGSASPRPRIYPVAPAMSVSELSYRVPPATPGCDPGGLGEVPSVHSRPAYFRPPGLGHPIFSPSHLASKTPPPLYLATDGRRPDLPPGLVGARGGLGTSRSLYSGLQSPGAPGPALGSFAFLPSGSTDCSPGDAAQGPLQPSPWPPTRDAVDPARPVARSLCKEGPPSRGASPPTPPVSIKSERLSPVTGTSGDFPRSFPYPLLLARPLAEPLRPSASLHRLTPDSWPR
What is the function of this protein?
Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes.  Activates transcription via this element.  May be involved in muscle-specific and/or growth factor-related transcription.
What are the official names of this protein?
Myocyte-specific enhancer factor 2B.
What is the protein family that this protein belongs to?
Belongs to the MEF2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RK33_LACSA
Sequence: MAKGKDVRIPVLLECTACVRNGVNVNKASTGISRYITQKNRHNTPNRLELRKFCPYCYKHTIHGEVKK
What are the official names of this protein?
50S ribosomal protein L33, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GPDA_ACISJ
Sequence: MKIVVLGAGAWGTALAMSAAAHAACHEVTLWARDAQQAQAMQAKRQNQRYLPGLAFPPGLHVASGDMGALAADADLVVVGTPMAALRGMLERLDGCAAPIAWLCKGFEADTGLMAHEVCAQVAPRLHSGVFSGPSFAQEVATAQPTAMVAASPRATVRDALVQAFHGPALRVYASEDIVGVEVGGAVKNVLAIATGLCDGLQLGMNARAALITRGLAEMTRLGLALGARPETFMGLSGLGDLVLTATGDLSRNRRVGLLLAEGRTLAQAVESLGHVAEGVYSARTVVQRARAVGVEMPIAECVVALLDGELRAAEAVARLMEREPTVERH
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBB8B_HUMAN
Sequence: MREIVLTQTGQCGNQIGAKFWEVISDEHAIDSAGTYHGDSHLQLERINVHHHEASGGRYVPRAVLVDLEPGTMDSVHSGPFGQVFRPDNFISGQCGAGNNWAKGRYTEGAELTESVMDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIINTFSILPSPKVSDTVVEPYNATLSVHQLIENADETFCIDNEALYDICSRTLKLPTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVAELTQQMFDAKNMMAACDPRHGCYLTVAAIFRGRMPMREVDEQMFNIQDKNSSYFADWFPDNVKTAVCDIPPRGLKMSATFIGNNAAIQELFTCVSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEEDEEYAEEEVA
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta 8B.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: UREE_RHOCA
Sequence: MSLMHRASRVLPAGGWSGAADHIALDYEARFLRRKRLVAASGAEFLVDLPEVTNLRGGEAFALEDGRLIEVRCGLEPVLVVTGDLTRLAWHVGNRHTPCQIEPDRLLIRDDHVLETMLRGLGARVERRMEPFRPESGAYGSGRTMGHDHGPFHVHA
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSTS_STAAB
Sequence: MKKWQFVGTTALGATLLLGACGGGNGGSGNSDLKGEAKGDGSSTVAPIVEKLNEKWAQDHSDAKISAGQAGTGAGFQKFIAGDIDFADASRPIKDEEKQKLQDKNIKYKEFKIAQDGVTVAVNKENDFVDELDKQQLKAIYSGKAKTWKDVNSKWPDKKINAVSPNSSHGTYDFFENEVMNKEDIKAEKNADTNAIVSSVTKNKEGIGYFGYNFYVQNKDKLKEVKIKDENCKATEPTKKTIQDNSYALSRPLFIYVNEKALKDNKVMSEFIKFVLEDKGKAAEEAGYVAAPEKTYKSQLDDLKAFIDKNQKSDDKKSDDKKSEDKK
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.
What are the official names of this protein?
Phosphate-binding protein PstS, PBP.
What is the protein family that this protein belongs to?
Belongs to the PstS family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: MTAC_METBF
Sequence: MLDFTEASLKKVLTRYNVALEKALTPEEAAEELYPKDELIYPIAKAIFEGEEDDVVEGLQAAIEAGKDPIDLIDDALMVGMGVVIRLYDEGVIFLPNVMMSADAMLEGIEYCKENSGATPKTKGTVVCHVAEGDVHDIGKNIVTALLRANGYNVVDLGRDVPAEEVLAAVQKEKPIMLTGTALMTTTMYAFKEVNDMLLENGIKIPFACGGGAVNQDFVSQFALGVYGEEAADAPKIADAIIAGTTDVTELREKFHKH
What is the function of this protein?
Harbors a corrinoid prosthetic group and acts as a methyl group carrier in methanogenesis in the methanol pathway.  The methyl group of methanol is first transferred to the corrinoid prosthetic group of MtaC in the cob(I)amide oxidation state.  This reaction is mediated by MtaB.  The methyl group from MtaC is then transferred to coenzyme M by MtaA.
What are the official names of this protein?
Methanol--corrinoid protein, Methanol:corrinoid methyltransferase 1 subunit of 27 kDa, MT1 subunit 27 kDa.
What is the protein family that this protein belongs to?
Belongs to the methylamine corrinoid protein family.
Protein: KV3A3_MOUSE
Sequence: DIVLTQSPASLAVSLGQRATISCRASESVDNSGISFMNWFQQKPGQPPKLLIYAASNQGSGVPARFSGSGSGTDFSLNIHPMEEDDTAMYFCQQSKEVPWTFGGGTKLEIK
What are the official names of this protein?
Ig kappa chain V-III region MOPC 70.
Protein: RL3_MALP2
Sequence: MKMILGRKIGMIQSFLEDGRRIPVTIIQAEPNVVLENKTQEKNGYVATKVGFQQIEEKKLNKPQKGYFKKIKTDAFKHTKEFRNVSGYNVGDKILVDIFNSGDKVDAQAITKGKGFTGAIKRWNFKVGPLGHGAGYPHRYQGSISFGRGGSQGQRVPKGQKMSGHYGHELVTISNLTVVSIELEKNLILVKGSVPGPVNSLVLLKTTVKSKKQVDPIKLSDPEAIARAIKEKEEQARLALEAKKAEAHQKAEAEKEAKKQEMLAKQKAAEEKQKAEAEKNEQPTATAEEAPAKTDDNATEKKEENNGGNQ
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: IF411_TOBAC
Sequence: MAGLAPEGSQFDARQYDAKMTELLGTEQQEFFTSYDEVYESFDAMGLQENLLRGIYAYGFEKPSAIQQRGIVPFCKGLDVIQQAQSGTGKTATFCSGILQQLDYSLVECQALVLAPTRELAQQIEKVMRALGDYLGVKVHACVGGTSVREDQRILQSGVHVVVGTPGRVFDMLRRQSLRPDNIKMFVLDEADEMLSRGFKDQIYDIFQLLPPKIQVGVFSATMPPEALEITRKFMNKPVRILVKRDELTLEGIKQFYVNVDKEEWKLETLCDLYETLAITQSVIFVNTRRKVDWLTDKMRGRDHTVSATHGDMDQNTRDIIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTQPENYLHRIGHSGRFGRKGVSINFVTKDDERMLFDIQKFYNVVIEELPANVADLL
What is the function of this protein?
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome.  In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).
What are the official names of this protein?
Eukaryotic initiation factor 4A-11, eIF-4A-11, ATP-dependent RNA helicase eIF4A-11.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. eIF4A subfamily.
Protein: RLMN_BRUA2
Sequence: MSISFDLTIDDTRDQLARHARASLEAKPSLIGMSREEMAAALIAAGVPERQVKMRISQLWHWLYVRGVSDFADMRNISKDLRAMLAQHFTIARPEVVEEQISQDGTRKWLFRFPPRGAGRPVEIESVYIPEEGRGTLCISSQVGCTLTCSFCHTGTQKLVRNLTSEEILAQLLTARDRLGDFPDKDTPDGAMVPAEGRKITNIVMMGMGEPLYNFEEVKKALLIASDGDGLSLSKCRITLSTSGVVPEIYRTGDEIGVMLAISLHAVRDELRDILVPINKKYPLAELIKACREYPGLSNAKRITFEYVMLKDINDSLDDAKLLVKLLQGIPAKINLIPFNPWPGTNYQCSDWEQIEKFADYVNAAGYASPIRTPRGRDILAACGQLKSESERLRKSERLALEAMMIAGHGE
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMA_PHOPR
Sequence: MTSTALNTAGYQQQLDEKAERIQNIFEDFETPELEVFASPAEHYRMRAEFRMWHEGEDLYYVMFNQETREKYRVDQFPAASRLINDLMPLLVEALKPSQTLRHKLFQVDFLSTLSGEILVSLLYHRQLDEEWEVEIKKLKQCLNDEGFNLNIIGRARKMKIVADRDYVIEKLNVFDQTLTYKQVENSFTQPNGEVAQKMLEWAVDCTQDSDGDLLELYCGNGNFSLALAKNFERVLATELAKPSVESAQYNIAVNNIDNVQIVRMSAEDFTDAMAGKREFRRLKAQNVDLQSYNCNTIFVDPPRSGMDEGTCRMVQGYERIMYISCNPDTLKENLEILSQTHKITRFALFDQFPYTHHMEAGVLLERK
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: TYB4_PONAB
Sequence: MSDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES
What is the function of this protein?
Potent inhibitor of bone marrow derived stem cell differentiation (By similarity).  Acts by inhibits the entry of hematopoietic pluripotent stem cells into the S-phase (By similarity).
What are the official names of this protein?
Thymosin beta-4, T beta-4.
What is the protein family that this protein belongs to?
Belongs to the thymosin beta family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RNPA_DEIGD
Sequence: MKGEREFRRVRQQGVALRDPLFTLRVTDYRPRHGEVWRPQAIIGIVVSKKTLRRAVDRNRARRRVREALRTLPGGLPPCRAILLPNPGVLTVPFPELQAALVRVLAQVPGRVKRKGGGPGGNRRSAPPGSAPLTDDGRLRGEP
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: DHB12_MACFA
Sequence: MESALPAAGFLYWVGAGTVAYLALRISYSLFTALRVWGVGNEAGVGPGLGEWAVVTGGTDGIGKSYAEELAKRGMKVVLISRSQDKLDQVSSEIKEKFKVETRTIAVDFTLEDIYDKIKTGLAGLEIGILVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSVCKMTQLVLPGMVERSKGAILNISSGSGMFPVPLLTIYSATKTFVDFFSQCLHEEYRSKGIFVQSVLPYFVATKLAKIRKPTLDKPTPETFVKSAIKTVGLQSRTNGYLIHVLMGWIISNLPSWIYLKIAMNMNKATRVHYLKKIKKN
What is the function of this protein?
Catalyzes the second of the four reactions of the long-chain fatty acids elongation cycle.  This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle.  This enzyme has a 3-ketoacyl-CoA reductase activity, reducing 3-ketoacyl-CoA to 3-hydroxyacyl-CoA, within each cycle of fatty acid elongation.  Thereby, it may participate in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.  May also catalyze the transformation of estrone (E1) into estradiol (E2) and play a role in estrogen formation.
What are the official names of this protein?
Very-long-chain 3-oxoacyl-CoA reductase, 17-beta-hydroxysteroid dehydrogenase 12, 17-beta-HSD 12, 3-ketoacyl-CoA reductase, KAR, Estradiol 17-beta-dehydrogenase 12.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ARIP4_MOUSE
Sequence: MSDESASGSDPDLDPDVELEDEEEEEEEEEVAVEEHDRDDEEGLLDDTSLEGMCGTEHAQLGEDGQRPPRCTSTTSSQSEPSEQLRHQGKILASEDPKKKRAQKPSHMRRNIRKLLREDQLEPVTKAAQQEELERRKRLEQQRKEYAAPIPTVPLEFLPEEIVLRASDGPQLPPRVLAQEVICLDSSSGSEDEKSSRDEVIELSSGEEDTLHIVDSSESVSEEDEEEEKGGTHVNDALNQHDALGRVLVNLNHPPEEENVFLAPQLARAVKPHQIGGIRFLYDNLVESLERFKTSSGFGCILAHSMGLGKTLQVISFIDVLFRHTPAKTVLAIVPVNTLQNWLAEFNMWLPAPEALPADSKPEEVQPRFFKVHILNDEHKTVASRAKVTADWVSEGGVLLMGYEMYRLLTLKKSLATSRPKKTKKRSHPVIIDLDEEDRQQEFRREFEKALCRPGPDVVICDEGHRIKNCQASTSQALKNIRSRRRVVLTGYPLQNNLIEYWCMVDFVRPDFLGTRQEFSNMFERPILNGQCIDSTPQDVRLMRYRSHVLHSLLEGFVQRRGHTVLKIHLPAKEENVILVRLSQIQRDLYTQFMDRFRDCGTSGWLGLNPLKAFCVCCKIWNHPDVLYEALQKENLANEQDLDVEELGSAGTSARCPPHGTKVKGEDSALPSSMGEATNSKFLQGVGFNPFQERGNNIVTYEWAKELLTNYQTGVLENSPKMVLLFHLIEESVKLGDKILVFSQSLSTLALIEEFLGKRDMPCLPGAEGQGTQKWVRNVSYFRLDGSTPAFERERLINQFNDPSNLTTWLFLLSTRAGCLGVNLIGANRVVVFDASWNPCHDAQAVCRVYRYGQKKPCHIYRLVADYTLEKKIYDRQISKQGMSDRVVDDLNPMLNFTRKEVENLLHFVEKEPAPQTSLDIKGIKESVLQLACLKYPHLITKEPFEHESLLLNRKDHKLTKAEKKAAKKSYEEDKRTSVPYTRPSYAQYYPASDQSLTSIPAFSQRNWQPTLKGDEKPVASVRPVQSTPIPMMPRHVPLSGGVSSASSTNTSMNFPINYLQRAGVLVQKVVTTTDIVIPGLNSSTDVQARINAGESIHIIRGTKGTYIRTSDGRIFAVRATGKPKAPEDGRMAASGSQGPSLASTSNGRHSASSPKAPDPEGLARPVSPDSPEIISELQQYADVAAARESRQSSPSISAALPGPPGQLMDNSTIPGTALGTEPCLGGHCLNSSLLVTGQPSGGRHPVLDLRGHKRKLATPSVTQESIRRRSRKGHLPAPVQPYEHGYPVSGGFAMPPVSLNHNLTTPFTSQAGENSLFMGSNPSYYQLSNLLADARLVFPVTTDPLVPAGPVSSSSTATSVTASNPSFMLNPSVPGMLPSYSLPFSQPLLSEPRMFAPFPSPGLPSNLSRGVSVYPGYMSPHAGYPAGGLLRSQVPPFDSHEVAEVGFSSNDDEDKDDDVIEVTGK
What is the function of this protein?
DNA helicase that modulates androgen receptor (AR)-dependent transactivation in a promoter-dependent manner.  Not able to remodel mononucleosomes in vitro.  Acts as an AR-coregulator in Sertoli cells.
What are the official names of this protein?
Helicase ARIP4, Androgen receptor-interacting protein 4, RAD54-like protein 2, Steroid receptor-interacting SNF2 domain-containing protein-like.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes in speckle-like nuclear compartments.
Protein: HEM1_METM7
Sequence: MLVVKADYKKYPIPVLEKMRIDEDEFYKKYEACVVVQTCNRIEAYFDTEVNSNVDDILKDFQGFDILKGKNATFHFLKVSCGMDSMILGENQILGQIKTSFQKAREFKKTSRYLDSLFLKAIHVGQRARTETKINEGGVSIGSAAVELAEKNFGLTNRNVLLIGAGEIGTLVAKALVEKHIKAVIVANRTYERAETLAKELKGMAVHFDKLREAVNFSDVIICATSSPHYILEKEDLIDVGNKIIIDIANPRDVDDSVRELENIELYTIDDLRNISDKNLQRRIEEIPTVEKIIEEEYDVLMKQIEKINVEEVLKEFNTYIEEIRVKELEKAIKLSKSKDPEEIMENFSKAFAKRITHDFVSYSLNTSKEDLMNSAWWKNGK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: DYR6_PROMI
Sequence: MKISLMAAVSENGVIGSGLDIPWHVQGEQLLFKAMTYNQWLLVGRKTFDSMGKLPNRKYAVVTRSKIISNDPDVVYFASVESALAYLNNATAHIFVSGGGEIYKALIDQADVIHLSVIHKHISGDVFFPPVPQGFKQTFEQSFSSNIDYTYQIWAKG
What is the function of this protein?
Key enzyme in folate metabolism.  Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
What are the official names of this protein?
Dihydrofolate reductase type 6, Dihydrofolate reductase type VI.
What is the protein family that this protein belongs to?
Belongs to the dihydrofolate reductase family.
Protein: PPR79_ARATH
Sequence: MSAVKSVSSFRLASLLRRENDPSAAMKLFRNPDPESTNPKRPFRYSLLCYDIIITKLGGSKMFDELDQVLLHLKTDTRIVPTEIIFCNVINFFGRGKLPSRALHMFDEMPQYRCQRTVKSLNSLLSALLKCGELEKMKERLSSIDEFGKPDACTYNILIHGCSQSGCFDDALKLFDEMVKKKVKPTGVTFGTLIHGLCKDSRVKEALKMKHDMLKVYGVRPTVHIYASLIKALCQIGELSFAFKLKDEAYEGKIKVDAAIYSTLISSLIKAGRSNEVSMILEEMSEKGCKPDTVTYNVLINGFCVENDSESANRVLDEMVEKGLKPDVISYNMILGVFFRIKKWEEATYLFEDMPRRGCSPDTLSYRIVFDGLCEGLQFEEAAVILDEMLFKGYKPRRDRLEGFLQKLCESGKLEILSKVISSLHRGIAGDADVWSVMIPTMCKEPVISDSIDLLLNTVKEDGPLSAMPQC
What is the function of this protein?
Involved during embryo development.
What are the official names of this protein?
Putative pentatricopeptide repeat-containing protein At1g53330.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
Protein: ARGJ_LODEL
Sequence: MMKNILLYKVLARYTSTKAARFVPKTGVYPKGYEVGGIHCGVKKDGKTFDLAILHNTHGKDASAAAVFTTNKFKAAPVQVSQKLIKETKGAGINSIVVNSGNANAVTGAQGMKDAEDMVIVTDSVLENKPNSTLVMSTGVIGNNLPIDNILSGIPKLALSHLGNSHQNWIDCATAICTTDTFPKLVSKQFTIGKDTYTLAGLCKGAGMICPNMATLLGFFVTDAPVSPSALQLILKYAVDRSFNSITVDGDMSTNDTIAAIANGAAGGELIDLNSSCAERYAELQKEITDFAQQLAQLVVRDGEGATKFITIKVKDALSYKDAKSIASSVANSSLFKTAMYGKDANWGRILCAIGYADVGNGSVVPQKTSVKFVPVDGSESLQLLQNGEPEKVDEERASEILADEDLVIEIDLGTGGGQGADFWTCDLSHEYVTINGDYRS
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: HPRK_THEPX
Sequence: MDKIPVETLIKDLNLEVIVEAKNNKIDITTSDVNRPGLQFSGFYEHFAYERVQIIGKVETTFIEQLPDDVLAERADRFFNYPIPCLIVTRDLNIRQEIIDAAQKHDRYLLRTKEASTKFINRLINYLDEKLAPQITIHGDLVDVYGIGVLLLGESGIGKSETALELIKRGHRLVADDAVEISKISEDKLQGSSPEIIRHFIEIRGIGILDIKTLYGVGSVRNSMNIDLVIQLEEWDEDKYYDRLGLEDDYIKFLDVKVPKLTIPVRPGRNLAIIVEVAAMNHRQKQMGYNAAHELNKKLLKQIGN
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).  The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc. ) in the growth medium.  Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: PURQ_CUTAK
Sequence: MVRIGVVTFPGTLDDQDAARAVRLAGAEPVSLWYASTDLAGVDAVILPGGFSYGDYLRAGALAAASPVMSSIRRAADGGLPVLGICNGFQVLCESHLLPGTLMRNEKRRFHCSVQQLQVASVDTVWTCDFRPSERIHIAAKHGEGNYVADAATVAALEANNRVVFRYTANPNGSVHDIAGITNEAGNVVGLMPHPEHSVEELTGAGTDGLGFFRSLMTFLSAQL
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCER1_MOUSE
Sequence: MTQTVNEREDPLNLGGGGWASSIPLRTWSSYHRRQRGAPVSKRRYRDGPKIEYEASRKQPKQQRSPGSWFQPSRGPYWALYSNWERCGGPWRPPLIAFQSPLCPAQMIRAYGLHPLCVCCCSCWSGPWNPGWERPPGRKKRWGRRGRGLRRHPRRSFPRNPPIDLSKMLRPVNLSGWRAPGMRAPRNTTQFIMNQVYEDMRQQEKLERQQAALRAQQAQEGGISPGDSTTNDAPHSGVEEDSQLPEDLYGFMQDPSLTFSPALMQHNQSPTPGLVEEEEKNVDDDECDVEVCDEKEESEEEEEEEVDRGSEDEDVDEEEVEAAGNGEEGEEDQEEEYMLEETGLEEGEQRAEEKFLPLGMPLSILVGDEEERENFMNYDYLSQEQIIPNVPEADLFMVPDISH
What are the official names of this protein?
Coiled-coil domain-containing glutamate-rich protein 1.
Protein: RL14_MYCBP
Sequence: MIQQESRLKVADNTGAKEILCIRVLGGSSRRYAGIGDVIVATVKDAIPGGNVKRGDVVKAVVVRTVKERRRPDGSYIKFDENAAVIIKPDNDPRGTRIFGPVGRELREKRFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.