PharMolix/UniProtQA huggingface dataset:
Protein: ACKA_AGARV
Sequence: MNVLVINCGSSSLKYQLINSDSEEVLAKGLCERIGIDGRLVYQKEGLDKEITEAPMPTHKEAIQMVLDALVNPKTGAVKSLAEIDAVGHRVVHGGEKFSDSVVITEEVIAQVEECNDLAPLHNPANIIGIRACQALMPNVPMVGVFDTAFHQTMPEKAYLYGLPYEYYEKYKVRRYGFHGTSHSFVSKEAASYLGMDLNNSKIIVAHLGNGASVSAVLNGKCVDTSMGLTPLEGLVMGTRSGDIDPSIMEFIAKKENLDIDGVMNVLNKKSGVAGMSGVSSDFRDLEAAYNEGNERAIAAVEVFSYRVAKYIGAYAAAMNGVDAIAFTAGIGENTSFVREKIMAYLGYLGIKIDRVTNDKTRGVEALISTADSSVKVCVIPTNEELAICRETVKLVG
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KI2L2_HUMAN
Sequence: MSLMVVSMACVGFFLLQGAWPHEGVHRKPSLLAHPGRLVKSEETVILQCWSDVRFEHFLLHREGKFKDTLHLIGEHHDGVSKANFSIGPMMQDLAGTYRCYGSVTHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVLAGESVTLSCSSRSSYDMYHLSREGEAHECRFSAGPKVNGTFQADFPLGPATHGGTYRCFGSFRDSPYEWSNSSDPLLVSVIGNPSNSWPSPTEPSSKTGNPRHLHILIGTSVVIILFILLFFLLHRWCSNKKNAAVMDQESAGNRTANSEDSDEQDPQEVTYTQLNHCVFTQRKITRPSQRPKTPPTDIIVYAELPNAESRSKVVSCP
What is the function of this protein?
Receptor on natural killer (NK) cells for HLA-Cw1, 3, 7, and 8 allotypes.  Inhibits the activity of NK cells thus preventing cell lysis.
What are the official names of this protein?
Killer cell immunoglobulin-like receptor 2DL2, CD158 antigen-like family member B1, Natural killer-associated transcript 6, NKAT-6, p58 natural killer cell receptor clone CL-43, p58 NK receptor CL-43.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: TEF4_HASHE
Sequence: NEVCPPGECQQYCCDLRKCKCINLSFYGLTCNCDS
What are the official names of this protein?
Augerpeptide hheTx4.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPE_MORIN
Sequence: MTLNLCVLTPNRIVWDSEVKEIILSTNSGQIGILPNHAPIATAVDIGILRIRLNDQWLTMALMGGFARIGNNEITVLVNDAEKGSDIDPQEAQQTLEMAEANLSKAEGKRQTIEANLALRRARTRVEAINMMS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, chloroplastic, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: ARP7_ARATH
Sequence: MEALVVDAGSKFLKAGAAIPDQSPAMIIPSQMKRMVDDGSSSADNPTTVFEDVTLDPIERGLIRDWDAMEDLLRYVVYTGLGWEEGNEGNILFTDPLCTPKAIREQLVQLMFETFNVSGFYASEQAVLSLYAVGRISGCTVDIGHGKIDIAPVLEGAVQHIASKRFELGGTELTKLFAQELGKTNPSMNLSMSDVEKLKEQYANCAEDEIAYKKTQNCEIEQHTLPDGQVISIGRERYSVGEALFQPSILGLEEHGIVEQLVRIISTVSSENHRQLLENTVLCGGTTSMTGFESRFQKEANLCSSAIRPTLVKPPEYMPENLGMYSAWVGGAILAKVVFPQNQHVTKADYDETGPSVVHRKCF
What is the function of this protein?
Essential protein required during embryogenesis and all plant development stages, probably through a chromatin-mediated regulation of gene expression.
What are the official names of this protein?
Actin-related protein 7.
What is the protein family that this protein belongs to?
Belongs to the actin family. Plant ARP7 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Localized in the nucleus during the interphase, but is released into the cytoplasm during the mitotic phase (PubMed:12609034).
Protein: SRP_PHAVU
Sequence: MRCAILYSYAKERAGPLKPGVNTVEDAVKTVVAPVYDRFHLVPVELLKYADRKVGELDRHVPSNVKKVSSQARSVVSEVRRDGVSTFAKTVYSKYEPTAEQCAVSAWRKLNQLPLFPQVANAVLPKAAYCTEKYNEVIVSSAEKGYRVSAYLPLVPTEKIAKVFSGN
What is the function of this protein?
Plays a role in plant defense.
What are the official names of this protein?
Stress-related protein, PvSRP.
What is the protein family that this protein belongs to?
Belongs to the REF/SRPP family.
Protein: CUTC_ERWT9
Sequence: MRQLEICCYGVECAVTAERAGADRIELCSAPAEGGLTPSAGALDSARRRVSIPVHPIVRPRGGDFCYSPSEFELMKSDISFIREQGFPGLVIGLLDVDGHVDQRRMRQVMQLSQGMDVTFHRAFDLCHNPLLTMAQIADLGVTRILTSGQQQSAESGLPLIRELIRQSNGPMIMAGAGVRLSNLQKFIDAGVMELHSSASQRVSSTMRYRKAGVSMCSETEVDEFSRTCVDADVVAAMKNVLMAASPGRVA
What are the official names of this protein?
PF03932 family protein CutC.
What is the protein family that this protein belongs to?
Belongs to the CutC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPO5_SCHPO
Sequence: MATKTQLELFTKLTSNDKAIRLSSAAQLIDSLSNEEELKYSLNRLTKGLSSGRESARIGFAVALTELLTRTKDIRATHVLDLLVKHNTASGNLKGQDERDFYFGLLFGLQSIVYSGILTHKESTIEDFQRVVDLLLQLSGKKNWLQDVCFYVIYKLVEQIPEISFSSNAFLAVNKLLQTPAVSKSTEGVGLFLCLTRVPDNVKSEEVAMANWEPAHPLHKSNLVTLSKIMRQADASETGGQNSAWKQKIPMVWKYIFEEYQRKTYSGLAPFHDFWAVVVDEGIFSSTSSLERKFWGFQIMELALDYVSSDNIGDIFSKNFLHCLINHLSDEDRYLYRAAKRVTSKLEKVSKQNPTLVYPIAIHLLGERGSLNFDRVTNTKLVEHILPLADEQGILQLFQLLLSYVKRCPEDIASDTKAVEWRRQWATDTMLSILRSKRSIKQEPWVRELLEIFIAYGYFEVPESEEVIPKFSEGTQNMFRLRLMSALSYLSSSAFQQSQTDHQLGDKNWPYVALNYLLELEKSPKNNLLISMDESVIEIVQKSLSVLHKVTKKIDKKAQHLQQLNAFQLLYSLVLLQVYAGDTDSIDVLEDIDNCYSKVFNKKSKRESTSNEPTAMEILTEVMLSLLSRPSLLLRKLVDMLFTSFSEDMNRESIHLICDVLKAKESVKDSEGMFAGEEVEEDAFGETEMDEDDFEEIDTDEIEEQSDWEMISNQDASDNEELERKLDKVLEDADAKVKDEESSEEELMNDEQMLALDEKLAEVFRERKKASNKEKKKNAQETKQQIVQFKVKVIDLIDNYYKTQPNNGLGFEFLIPLLEMILKTKHKVLEEKGQAVFRNRLSKLKWTEEKPSSKNVLEALKKVHVLCGKKASLGSTGSSISQLLLKLLADTPYLKEGVEVYLKSFLLWIQEPSKSHYNANIFHDFINWGAQQRLKHQQTSTAASSPQKTGHHENEKTNH
What is the function of this protein?
Plays an important role in the regulation of rRNA transcription.  Binds to rDNA promoter fragments.
What are the official names of this protein?
rDNA transcriptional regulator pol5, DNA polymerase V, POL V, DNA polymerase phi.
What is the protein family that this protein belongs to?
Belongs to the MYBBP1A family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNS1B_RATTI
Sequence: MGLXKSFALFSLLVLVLGWVQPSLSGESRESSADKFKRQHMDPDSPSKSSPTYCNQMMKRQGMTKGSCKRVNTFVHEPLEDVQAICSQGQVTCKNGRNNCYKSSSTLHITECHLKGSSKYPNCDYTTTDSQKHIIIACEGNPLVPVHFDDSV
What is the function of this protein?
Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides.  Acts on single-stranded and double-stranded RNA (By similarity).
What are the official names of this protein?
Ribonuclease pancreatic beta-type, RNase 1 gamma.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: CTHL2_CHICK
Sequence: MLSCWVLLLALLGGVCALPAPLSYPQALIQAVDSYNQRPEVQNAFRLLSADPEPGPGVDLSTLRALNFTIMETECTPSARLPVDDCDFKENGVIRDCSGPVSVLQDTPEINLRCRDASSDPVLVQRGRFGRFLRKIRRFRPKVTITIQGSARFG
What is the function of this protein?
Binds bacterial lipopolysaccharide (LPS).  Has potent antimicrobial activity against Gram-positive and Gram-negative bacteria (in vitro).  Has hemolytic activity (in vitro).  May play a role in the innate immune response.
What are the official names of this protein?
Cathelicidin-2, CATH-2, Fowlicidin-2, Myeloid antimicrobial peptide 27.
What is the protein family that this protein belongs to?
Belongs to the cathelicidin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CLCA_MOUSE
Sequence: MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAPGRATRRAAGGPDAVDGVMNGEYYQESNGPTDSYAAISEVDRLQSEPESIRKWREEQTERLEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADLIGYVAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLISLKQAPLVH
What is the function of this protein?
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.  Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge (By similarity).
What are the official names of this protein?
Clathrin light chain A, Lca.
What is the protein family that this protein belongs to?
Belongs to the clathrin light chain family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, spindle. Note=Cytoplasmic face of coated pits and vesicles.In complex with TACC3 and CKAP5 (forming the TACC3/ch- TOG/clathrin complex) localized to inter-microtubule bridges in mitotic spindles.
Protein: EFC1_HUMAN
Sequence: MARPSPLCLLLLLTLLTPIVPSNSLLTEPPFRWRFYLHETWTQGNRLSTVTLATVDCQPHGCQAQVTFNFTSFKSVLRGWSNPTICFVYDQTHSNCRDYWVDTNGGCPYAYCRMHVTQLHTAKKLQHTYRLTSDGRTTYFLTIPDPWDSRWVSGVTGRLYRWPTDSYPVGKLRIFLTYIRVIPQVLSNLKDQADNIKHQEEVINTLVQSHPKADMVTYDDKAEAGPFSWITLVRHGARLVNMAGLVNLSHCFLCTALSQPPLVAVPLPQAFNTSGNHTAHPSGVFSEQVPLFRDPLQPQFPFCYTTPNSSWCNQTYSGSLSNLSAPAGGYFWCNFTLTKHLNISSNNTLSRNLCLPISLVPRLTLYSEAELSSLVNPPMRQKRAVFPPLVIGVSLTSSLVASGLGTGAIVHFISSSQDLSIKLQMAIEASAESLASLQRQITSVAKVAMQNRRALDLLTADKGGTCMFLGEECCYYINESGLVETSLLTLDKIRDGLHRPSSTPNYGGGWWQSPLTTWIIPFISPILIICLLLLIAPCVLKFIKNRISEVSRVTVNQMLLHPYSRLPTSEDHYDDALTQQEAAR
What is the function of this protein?
TM anchors the envelope heterodimer to the viral membrane through one transmembrane domain.  The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane (By similarity).
What are the official names of this protein?
Endogenous retrovirus group FC1 Env polyprotein, Envelope polyprotein, Fc1env, HERV-F(c)1_Xq21.33 provirus ancestral Env polyprotein, HERV-Fc1env.
What is the protein family that this protein belongs to?
Belongs to the gamma type-C retroviral envelope protein family. HERV class-I F(c)1 env subfamily.
What are the subcellular locations of this protein?
Virion. SUBCELLULAR LOCATION: [Transmembrane protein]: Cell membrane; Single-pass membrane protein.
Protein: GRPE_ACIET
Sequence: MSENQNPSPSPEEIEAAMSANAADELNRLQGELAELKAKSADLADQFLRAKAEAENARRRAEDEVAKARKFGIESFAESLLPVCDSLDAALAIENATAEQLREGSDATLRQLMSALERNKVVIVNPEAGTKFDPHQHQAISMVPADQEANTVVSVLQKGYLISDRVLRPALVTVAAPK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IMP4_CANGA
Sequence: MLRRQARERREYLYRKAQELQETQLQQKRQIIKQALAQGKPLPKELAEDEQLQKDFRYDQSMADNEDEAGVDDEYSASSGIVEARVIVTTSRDPSSRLAQFAKEIKLLFPNAVRLNRGNYVMADLVSACKKSGTTDLIVLHEHRGVPTSLTVSHFPYGPTAFFSLHNVVLRHDILNRGNQSEVNPHLIFDNFTTPLGNRVVTILKNLFPPGPKKDSSRVITFANRGDFISVRQHVYVRTKDGVEMAEVGPRFEMRLFELRLGTLENKDADVEWQLRRFVRTANRKDYL
What is the function of this protein?
Component of the U3 small nucleolar ribonucleoprotein.  Required for the early cleavages at sites A0, A1 and A2 during 18S ribosomal pre-RNA processing (By similarity).
What are the official names of this protein?
U3 small nucleolar ribonucleoprotein protein IMP4, U3 snoRNP protein IMP4.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: MNMC_ECOSM
Sequence: MKHYAIQPANLEFNAEGTPVSRDFDDVYFSNDNGLEETRYVFLGGNQLEARFPEHPHPLFVVAESGFGTGLNFLTLWQAFDQFREAHPQAQLQRLHFISFEKFPLARADLALAHHHWPELAPWAEQLQAQWPMPLPGCHRLLFDEGHVTLDLWFGDINELTSQLDDSLNQKVDAWFLDGFAPAKNPDMWTQNLFKAMARLARPGGTLATFTSAGFVRRGLQEAGFSMQKRKGFGRKREMLCGVMEQTLPLPCSTPWFNRTGSNKQEAAIIGGGIASALLSLALLRRGWQVTLYCADEAPALGASGNRQGALYPLLSKHDEALNRFFSNAFTFARRFYDQLPVKFDHDWCGVTQLGWDEKSQHKIAQMLSMDLPAELAVAVEANAVEQITGVATNCSGITYPEGGWLCPAELTRNVLELAQQQGLQIRYQHQLQDLSRKDDGWLLNFAGDQQATHSVVVLANGHQISRFSQTSSLPVYSVAGQVSHIPTTPELAKLKQVLCYDGYLTPQNPANQHHCIGASYHRGSEDTAYSEDDQQQNRQRLIDCFPQAQWAKAVDVSDKEARCGVRCATRDHLPMVGNVPDYDATLVEYASLAEKKDEAVSAPVYDDLFMFAALGSRGLCSAPLCAEILAAQMSEEPIPMDASTLAALNPNRLWVRKLLKGKAVKAG
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4210_RHOJR
Sequence: MQPGGQPDMSALLAQAQQMQQQLMAAQQEMAEAEVTGQAGGGLVTATVKGTGEVVGLKIDPKVVDPDDVETLQDLVIGAIEDASNKAQEIAAQKLGPLAGGFGGGGLPGLPGF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein RHA1_ro04210.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RS15_PELUB
Sequence: MTKKAEELKMHEKDTGSSEVQIALLTGKIETLSAHIKQFKKDKHSSVGLLRAVNRRKKLLEYLKKNKFDSYKNVLTQLNLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: GR98A_DROME
Sequence: MEQMSGELHAASLLYMRRLMKCLGMLPFGQNLFSKGFCYVLLFVSLGFSSYWRFSFDYEFDYDFLNDRFSSTIDLSNFVALVLGHAIIVLELLWGNCSKDVDRQLQAIHSQIKLQLGTSNSTDRVRRYCNWIYGSLIIRWLIFIVVTIYSNRALTINATYSELVFLARFSEFTLYCAVILFIYQELIVGGSNVLDELYRTRYEMWSIRRLSLQKLAKLQAIHNSLWQAIRCLECYFQLSLITLLMKFFIDTSALPYWLYLSRVEHTRVAVQHYVATVECIKLLEIVVPCYLCTRCDAMQRKFLSMFYTVTTDRRSSQLNAALRSLNLQLSQEKYKFSAGGMVDINTEMLGKFFFGMISYIVICIQFSINFRAKKMSNEQMSQNITSTSAPI
What is the function of this protein?
Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
What are the official names of this protein?
Putative gustatory receptor 98a.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr2a subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EIF3B_AEDAE
Sequence: MAKKKGENYDSDGGDDQDYDEEPNFDDPEGFVDDVSDEELLGDFLKQKPCESDGVENVIVVDNIPVVGPARFHKLQGVLEKLFKTAGTIVNIHYPKDDEENTRGYAFIEFKNPEMAEEAVKAFNNYRLDKSHTLLVNLFSDFQKYSDIPKEWSPPEPQPYKMQNDLYNFITEPDAQDQFCVIAESSPGAVQVQFWQNTQPEPVELLTRDRFTETYVKWSPLGTYIVTFHKQGVVIWGGSNFTKINKFPHSGTQYVDFSPCEQYLVTYGPNGQKIIIWDIRTGTEKRSFISDGTSNMSMFRWSHDDKYVARMGDNAIHVYETSTFYLLDKKSIKVQGIRNFSWSPTDNIIAYWMSEDLEAPARVTLLEIPRKNEIRNKNLFNVADCKIHWQKSGDYLCVKVDRYSKSKKDKKDADVKFLGMFYNFEIFHMREKDIPVDSVEVKETILAFAWEPVGSKFAIIHGDPASANVSFYEAKKGQEPTMLKKLEKKICSHLFWSPRGQFIVLANLQAGSFEFVDTNDFTIMKSGDHFRASEVEWDPTGRYVVTGTSGKVKEDHGYHIWSFQGKILKRVNLKNFILFLWRPRPPTLLSDEKQKEIRKNLKKYYAQFESKDRIRMTRASKELLEKRAKLREQFVEYRTKRVSEWEEQKYRRMQLRNNIDTDTLDADPDNVEEEIVEILVREDTTLLE
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit B, eIF3b, Eukaryotic translation initiation factor 3 subunit 9.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OLEC_STRMK
Sequence: MNRPCNIAARLPELARERPDQIAIRCPGRRGAGNGMAAYDVTLDYRQLDARSDAMAAGLAGYGIGRGVRTVVMVRPSPEFFLLMFALFKLGAVPVLVDPGIDRRALKQCLDEAQPEAFIGIPLAHVARLVLRWAPSAARLVTVGRRLGWGGTTLAALERAGAKGGPMLAATDGEDMAAILFTSGSTGVPKGVVYRHRHFVGQIQLLGSAFGMEAGGVDLPTFPPFALFDPALGLTSVIPDMDPTRPAQADPVRLHDAIQRFGVTQLFGSPALMRVLAKHGRPLPTVTRVTSAGAPVPPDVVATIRSLLPADAQFWTPYGATECLPVAVVEGRELERTRAATEAGAGTCVGSVVAPNEVRIIAIDDAPLADWSQARVLAVGEVGEITVAGPTATDSYFNRPQATAAAKIRETLADGSTRVVHRMGDVGYFDAQGRLWFCGRKTQRVETARGPLYTEQVEPVFNTVAGVARTALVGVGAAGAQVPVLCVELLRGQSDSPALQEALRAHAAARTPEAGLQHFLVHPAFPVDIRHNAKIGREKLAVWASAELEKRA
What is the function of this protein?
Involved in olefin biosynthesis (PubMed:27238740, PubMed:28029240).  Catalyzes the conversion of beta-hydroxy acid substrates to beta-lactones in the presence of ATP (PubMed:28029240).  Can use all four stereoisomers of 2-hexyl-3-hydroxydecanoic acid (PubMed:27238740).
What are the official names of this protein?
Olefin beta-lactone synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: SYL_PYRHO
Sequence: MAELNFKAIEEKWQKRWLEAKIFEPNIRDKPKEKKFYITVAFPYLSGHLHVGHARTYTIPDVIARFKRMQGYNVLFPMAWHITGSPIVGIAERIKNRDPKTIWIYRDVYKVPEEILWTFEDPINIVKYFMKAAKETFIRAGFSVDWSREFYTTSLFPPFSKFIEWQFWKLKEKGYIVKGAHRVRWDPVVGTPLGDHDLMEGEDVPILDYIIIKFELRENGEVIYLPAATLRPETVYGVTNMWVNPNATYVKAKVRRKDKEETWIVSKEAAYKLSFQDREIEVIEEFKGEKLIGKYVRNPVSGDEVIILPAEFVDPDNATGVVMSVPAHAPFDHVALEDLKRETEILEKYDIDPRIVENITYISLIKLEGYGDFPAVEEVNKLGIKSQKDKEKLEQATKTIYKAEYHKGIFKVPPYEGKPVQEVKEAIAKEMLEKGIAEIMYEFAEKNVISRFGNRAVIKIIHDQWFIDYGNPEWKEKARKALERMKILPETRRAQFEAIIDWLDKKACARKIGLGTPLPWDPEWVIESLSDSTIYMAYYTISRHINKLRQEGKLDPEKLTPEFFDYIFLEEFSEDKEKELEKKTGIPAEIIHEMKEEFEYWYPLDWRCSGKDLIPNHLTFFIFNHVAIFREEHWPKGIAVNGFGTLEGQKMSKSKGNVLNFIDAIEENGADVVRLYIMSLAEHDSDFDWRRKEVGKLRKQIERFYELISQFAEYEVKGNVELKDIDRWMLHRLNKAIKETTNALEEFRTRTAVQWAFYSIMNDLRWYLRRTEGRDDEAKRYVLRTLADVWVRLMAPFTPHICEELWEKLGGEGFVSLAKWPEPVEEWWNETIEAEEEFIRSVMEDIKEIIEVAKIENAKRAYIYTAEDWKWKVAEVVSEKRDFKSSMEELMKDSEIRKHGKEVAKIVQKLIKERTFDVKRINEEKALREAKEFMEKELGIEIIINPTEDKGGKKKQAMPLKPAIFIE
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBSD_ECO27
Sequence: MKKGTVLNSDISSVISRLGHTDTLVVCDAGLPIPKSTTRIDMALTQGVPSFMQVLGVVTNEMQVEAVIIAEEIKQHNPQLHETLLTHLEHLQKHQGNTIEIRYTTHEQFKQQTAESQAVIRSGECSPYANIILCAGVTF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_SALPB
Sequence: MSDSLRIIFAGTPDFAARHLDALLTSGHNVVGVFTQPDRPAGRGKKLMPSPVKVLAEEKGLPVFQPVSLRPQENQHLVADLHADVMVVVAYGLILPKAVLDMPRLGCINVHGSLLPRWRGAAPIQRSLWAGDAETGVTIMQMDVGLDTGDMLYKLACPITAEDTSGSLYNKLAELGPQGLITTLKQLADGTATPEAQNEALVTHAEKLSKEEARIDWSLSAAQLERCIRAFNPWPMSWLEIDGQPVKVWQASVIEDATQSLPGTILAATKQGIQVATGKGILNLLSLQPAGKKAMSAQDLLNSRREWFIPGNRLA
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: COXX_PROMT
Sequence: MVSSTSELITQPVNREEVVPSRKRIKLPAWLEVVKPRLIPLLLATTVGGMALSEEWPLPSPRLACTLGGGALAAAAAGALNCLWEQDLDKRMKRTSNRALPSGRLSQSSVFIGAVACTLVSSALLVSGVNCLAAGLTLLGLCSYVLLYTAFLKPRTSQNIVFGGVAGAIPPLVGASAAAGHIGLGGWWLFSLVMVWTPAHFWALAILLKEDYRSVGIPMLPTVSGPFVTAKAISVYGYLTVFLSFLGCFVLPEGGLLYGILLLPYNSRLLQLVSRLRDNPEDLDRAKGLFRWSILYMFGVCFLLVISRLQVSIVFNDQLIALIKDFSTGFS
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: QTRT2_DROWI
Sequence: MKFLVENINKNSGRLGLLDLKAAGGGIQLKTPLLMQTTKGGSIPYLSADLFENYVQNKNGQEPVPVLLQLTLSTMQQMAESLALWPASLSHYLGFPGQGNVLLLRDPCESTPSGGNDRDVAPIFTRQGKESLTPERYMEIIASFKPDIYQGLCDADTNLESSKKRVQKSVDRTERFMDYIYEQHGKLQSTSSSLLAPIVGGYNIFARTQSIKHARQQPEGKYSGYILEGFHNNGLSATALDGSQLLPIVEHCVKQLEENKIKMMPGAYSPLIILELIHIGVDVFDTSYAYCAAVNFKALVFNYDEKSIEPRPTPFLDITDEAIKEEFVPLLDNCKCLTCQKHTRAYVHHLYKTNELLGPILLMIHNLHHFMGFFETIRSSIAQDKLPKLIDLVCKQNGDSKVDYSIEKNVKVISKAVVGKGFETTTES
What is the function of this protein?
Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase accessory subunit 2, Queuine tRNA-ribosyltransferase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_AYWBP
Sequence: MTKVVVGLSGGVDSAVAAFLLKKQGYLVEAVFMRNWDSNLNFDIQGNPTLNDICPQELDYKDALKVSEQLGIKLHRVDFIEEYWQKVFMSFIKAFENNLTPNPDILCNNEIKFRAFIEYVTTKLAPRYIAMGHYANIIYETFSEQKLFPQLACAVDQNKDQTYFLSQLATKQLQNILFPLGNLTKQEVRQIALENNLINATKKDSTGICFIGERNFFQFLSNYLPAQKGDIKTLDGTFLAHHKGVMYYTIGQRKNLGLGDFSSQKPWFVVGKHLQTNTLYVEQGNTHPYLYSDKALISDIVWRGKKTNLHLQAKMRYRQPNQDVILTWIDQNTLEIYYPQTIKAVTPGQICAFYNNNICCGAGVIKEVYFQGTKRLYT
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.