PharMolix/UniProtQA huggingface dataset:
Protein: ADDA_PEDPA
Sequence: MADREYTLSQKQAINSSGHNILVSASAGSGKTSVLVERVIQKIINGEDVDRLLVVTFTEAAASEMKERIRAAIVKKINEVSDIELQNHFSMQLNKLNNANISTLHAFCMSIIRNYYYIIDLDPTFRIMDPTESELLKESVWADLREELYERDEDGKFALLTRNFSSDRSDEGLQDLILELFEFSNANPDPQAWLQQIAKNYEVPSDNVMDMEFIQQLLTEVKTKLMRIYRKDLDLTEQAINGGEPLKNAAEKFQNEVDDLKTIIDSLNGSWDDVQQAVSKMKFAQLPRGKKEEVQEFNAYAKSIRNDFKDEFNTIADKYFKLSSEQMIAVFKDAHDLMMKLIEVQNQFAERFLQEKLTRRSLDFSDLEHFALQIVLDDSEEGQAIRRDFQQKFNEVIVDEYQDINPLQETILTSVASPDPGNMFMVGDVKQSIYAFRMADPSLFISKNNQFKDEEQADERIILAENFRSMRNVDDFTNLIFNQVMDTEVGEIEYDDDAQLQFGAKYYPDEVQNNTEVMIYDDSQTDINDKEATPIISNKNDGQLQMIAQRIQKLFADHTQIYDKKEQKMRDLEYSDIALLHSTGSNNLEIVDTFKKYGIPIQVNNAQDYFQTTEVSIMMALLKIIDNPYQDIPLAAVLRSPMVGLKENELAFLRIGKKNGHYFEALLYFLNEAKLDSNNEFQMQLKTKITHFLEQLDHFSKLARQSTLVDLLWAIYDETGYLDYVGGMPDGPQRQNNLHALYDRAKGYEESSFKGLFQFVRFVEKMRDKNKDLAENPVVTDVKAVKLMTIHGSKGLEFPIVFLIDAEHGFNTMDEKGRYVLDRDAGMGITLKDFIHRLEIDTVQKNWIISIKKQKALAEKLRVLYVALTRAEQKLIITGAVNSADDTLNKWAEAVDTDETLIPAEARSKVSNFLDWIGMAIMRVPSVVEKYADYNTRKLQGTLIPDVELKIINSSELMDQQGLTALKSAQIPELQQLNAFDDIADVDKFKQIMNFKYHDEAATTTTAYQSVSEIKRVFDDPDKFELNFSEVDADQHIKPQNRFVTESLMAPRFMNEATKPKAAEIGTATHLILQQLDLNQPINETIIKDKIGELVMNRVLDEQVANRIRISTILDFFDSDLGQLMINHPENVHREEAFSLLLPAKGLFPKVKGDDDVLIHGIIDAYFEMEDRVILLDYKTDFVLPGSVEQGIEKVINRYQGQVNLYAQALGSILKRPVNEKYLYLLSIGRLVEIQ
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.
What are the official names of this protein?
ATP-dependent helicase/nuclease subunit A, ATP-dependent helicase/nuclease AddA, DNA 3'-5' helicase AddA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddA subfamily.
Protein: METJ_YERPE
Sequence: MAEWNGEYVSPYAEHGKKSKQVKKITVSIPLKVLKILTDERTRRQVNNLRHATNSELLCEAFLHAFTGQPLPNDEDLRKERSDEIPEAAKILMRELGVDPDTWEY
What is the function of this protein?
This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.
What are the official names of this protein?
Met repressor, Met regulon regulatory protein MetJ.
What is the protein family that this protein belongs to?
Belongs to the MetJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VU8_HHV7J
Sequence: MKNFETMAEQYKTLPCVGQLNDGLLRELKNLCRFTDFPGIRLLTERHRNECLSLIWPKNLWLRLAQPVDVAGYSEQQLAELNDHYQGFKENLCLIGAIQIGRKDVPIFVGKSSRIFCHDLEDDVLYYIAEDFDKFVRFGILGTNVITCSEPVYTRFYYDGPKFEKLETLKDLGLLQEPLNLNSSLRFNRKTALALKALRRNYISMLSELDELARCKTLAEIEHFVSINTGLKLRLETPIFTALILQDRKNIHCGTSDQKRFEEQEALFEKVVVLGFLNISAEDYGLRPILCIGETGAIYYYDWIDKVLTRIADCLLTFARIGFARYCGDFGYDKIGKVTARFGRLSTLGSAPVQQYSWYLSK
What are the official names of this protein?
Protein U8.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae US22 family.
Protein: ECFA_MOOTA
Sequence: MIAIQGATYIYPGSTVPALEKIDLAIEPGEFLAITGPNGSGKSTLARLLNGLLRPRQGRVLVDGMDTGDDTALITIRRRVGMVFQDPDNQLVAATVAEDVAFGLENLGLPPAEIEKRVDLALRSVGLEDLAARPPHLLSGGQKQRLALAGVLAMEPRYLVLDEATAMLDPVAREEILEQVLRLRQEQGIAIILITHLMEEAVRADRMLIMKSGRIFWQGSPRELSYQERILAAAGLRLPAVIALAKSLRQGGIKLATNPVCVEELARALWKLASRE
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA, ECF transporter A component EcfA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: BBM_ARATH
Sequence: MNSMNNWLGFSLSPHDQNHHRTDVDSSTTRTAVDVAGGYCFDLAAPSDESSAVQTSFLSPFGVTLEAFTRDNNSHSRDWDINGGACNNINNNEQNGPKLENFLGRTTTIYNTNETVVDGNGDCGGGDGGGGGSLGLSMIKTWLSNHSVANANHQDNGNGARGLSLSMNSSTSDSNNYNNNDDVVQEKTIVDVVETTPKKTIESFGQRTSIYRGVTRHRWTGRYEAHLWDNSCKREGQTRKGRQVYLGGYDKEEKAARAYDLAALKYWGTTTTTNFPLSEYEKEVEEMKHMTRQEYVASLRRKSSGFSRGASIYRGVTRHHQHGRWQARIGRVAGNKDLYLGTFGTQEEAAEAYDIAAIKFRGLSAVTNFDMNRYNVKAILESPSLPIGSSAKRLKDVNNPVPAMMISNNVSESANNVSGWQNTAFQHHQGMDLSLLQQQQERYVGYYNGGNLSTESTRVCFKQEEEQQHFLRNSPSHMTNVDHHSSTSDDSVTVCGNVVSYGGYQGFAIPVGTSVNYDPFTAAEIAYNARNHYYYAQHQQQQQIQQSPGGDFPVAISNNHSSNMYFHGEGGGEGAPTFSVWNDT
What is the function of this protein?
Transcription factor that, in opposition to HDG1, promotes cell proliferation and morphogenesis via transcriptionnal activation of meristem and cell proliferation genes, but prevents differentiation, especially during embryogenesis (PubMed:12172019, PubMed:25564655).  Binds to the promoter and triggers the expression of epidermally expressed genes such as GSO1, GSO2, ACR4 and WER, and of HD-ZIP homeobox genes including PDF2, HDG1, HDG5, HDG7, HDG8, HDG11, ANL2, PDF2 and ATML1 (PubMed:25564655).
What are the official names of this protein?
AP2-like ethylene-responsive transcription factor BBM, AtBBM, Protein AINTEGUMENTA-LIKE 2, Protein BABY BOOM.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. AP2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ETFL_ASFB7
Sequence: MDFQNDFLTNPLRVTLYNPAENEYTKTFIFLGSVPANVLQACRKDLQRTPKDKEILQNFYGKDWEKKLSQYVVGGDSDDLDEFEKLFVEDSGEETNVMMPEIETMYSEYSIFPEDTFKDIREKIYVATGIPPYRQHIFFFQNNALQVTYRLLLSGSGVALDIRDYKKEFQQVGGLNIDASMESQKDELYVEALDSFQLIKNIHHIFVADLNTLVAPMRRQISIAMEDNYQFDLLYYGLIMKYWPLLSPDAFKLLVQSPLQMEKQYPALSPSLTSLKKRLLLEQKLINFTYARAQQVIAKYEGNRLTRGTLAVTSAMIKISPLVNIQINVRNVFDLFPATPDIPQLVVFFYSKTGPTVVSKHHITSTEPEKFSNKTFRVPTIILIRFINKKAFILTIQNNGHYFIESNWSENERHDFNSVVSTLNNFINPIIHTINDMGPAAFPRGGSLPLPSNEDIQISISSMSVSTFWPYTLSSKGFTELKSRWREYEQAGIISVRGLQQTGIYNFLFKKGIYSYDPHEIERMIIISSGPGRKMDINVALLQNTYAYLFDANVAARWETIYGGRNIRIYHRVTDIKIEMFNITQEEFNYLWVYLFVFLDNLITGPDKILVNKLSQLHDKQQGKGASQLRALQEQDPDLYDLRKYDTQATVYSVLCQHPRPPVIYSEAEVKSMPPAKRKELVKYWNFTEGVPAYYSCPHPDYPHLSLLEGRHPLNYCLPCCQKTKALLGTKRFYINNTCLTKHTFVEQDLEDLNTQTSRHTLSYGKKIPVNRIAFLPHQIADELFLNTIKEPDIFCIVGVEQTMLGISNAGLFYSLARILDLAPKALAIEIAKAANTPQYYILGNGAGNMFSSGAELANLILQTFVEQKNQLLQWDTTWQDIFLDLVAICYDLHCVFFKDKQGDIEFEVSPSTIQKILSPSKKIAIIFDTDEGIYPMAITQQKRFLKNSEAQYIFTEDDPVMEVVQSMSEFMCKDNWWDIHDVKNIPGYTVGKKLINRHNFCYALLIDSDTDRPIYFPIRLSSYIHDDIPIDFDLRPTQIASFEETWKFITLFNKQYKQYEIVPSAVLQNIKKEFVGFLSEGKTGLYFYYAPTQTLPATLEKLPIATLTIDPRDIDQAILYPLEEPYPQQNKANKAFYINHLYKFLLIEFFDVLYGLQSNSTRKHIENLFQKTDFQKITSVTEFYTKLSDFVDLNDIHTIKHILETTDAEHALKVLQKNIFNFDYTLLSPLQSYTYDELCQHLKKLLTPRIEFYEDIETIDRGLINIYTSCQYSTLNQPQCKKKRLRIPVNHFENYIHILAADILNPLKHSTLLLTGLGVIDDLQFILRPQEIISVKNKF
What is the function of this protein?
Putative initation factor.
What are the official names of this protein?
Early transcription factor large subunit homolog, pG1340L, VETFL homolog.
What is the protein family that this protein belongs to?
Belongs to the asfivirus G1340L family.
What are the subcellular locations of this protein?
Virion. Note=Found in association with viral nucleoid.
Protein: MTCL1_MOUSE
Sequence: METLNGPAGGGAPDTKPQPAGQHHRHHHLHPLAERRRLHRAPSPARPFLKDLHTRPATATPSAGRAPTPAAPRSPSLAGKAPPSPGPPAAPGRLSRRSGVVPGAKDKPPPGAGARSAGGAKAVPGTRRAARAGPAEPLSRVGRPTGAEPPPAVAKGRKTKRGPGTPPARAVVPPARASRVPAVTLSVTSVAGCRINHTDSSSDLSDCASEPLSDEQRLLPAASSDAESGTGSSDREPIRGAPTPSSGSRGPPPGSPEPPILLAAPPVASACLGGRSSPGGASTGSPGPGSQEDVGGRAPPERTILGTSKEPSLGEQPRLLVVAEEEELLREMEELRSENDYLKDELDELRAEMEEMRDSYLEEDGYQLQELRRELDRANKNCRILQYRLRKAEQKSLKVAETGQVDGELIRSLEQDLKVAKDVSVRLHHELETVEEKRAKAEDDNETLRQQMIEVEVSRQALQNEVERLRESSLKRRGSREMYKEKKLVNQDDSADLKCQLQFVKEEASLMRKKMAKLGREKDELEQELQKYKSLYGDVDSPLPTGEAGGPPSTREAELKLRLKLVEEEASILGRKIVELEVENRGLKAEMEDIRVQHEREGTGRDHVPSTPTSPFGDSMESSTELRRHLQFVEEEAELLRRSISEIEDHNRQLTHELSKFKFEPHQESGWLGDGVSKGPAASVPLQEELKSARLQIDELSGKVLKLQCENRLLLSNAQRGDLAAHLGLRAPSPRDSDAESDAGKKESDGEEGRLPQPKREGPVGGESDSEDMFEKTSGFGSGKPSEASEPCPAELLRVREDTECLVTIKLEAQRLERTVERLISDTDGFIHDSGLRGNGLASPGVQGGGGEGNSPSEPHLLETINVRMKAFRKELQAFLEQMSRIVDGLSPLSHLTESSSFLSTVTSVSRDSPIGTLGKELGPDLQSKLREQLEWQLNQDRGDEREGLRLRATRELHRRADGDSGSHHGLGGQSCFNLEMEEDHLYALRWKELEMHSLALQNTLHKRTWSDEKNLLQQELRSLKQNIFLFYVKLRWLLKHWRQGKQMEEGGEDLEESEHPENVPGLAELGVQGVHQTDGIDQEDADQGCSLPMGEHAPHSLVQISEHGSRLQSSDGGPLNKQVVENQQLFRALKALLEDFRSELREDEHARLRLQQQYASDKAAWDVEWAVLKCRLEQLEEKTEKSLGELDSSAEGKGALKKEREVHQKLLADSHSLVMDLRWQIHHREKNWNREKVELLERLDSERQEWGRQKEELLWRVEQLQKEKSPRRSGSFLCSRREDDTRPYPHQGSLHSSRPVSMWPCEDADSIPFEDRPLSKLKESDRCSASENLYLDALSLDDDPGDPPPLRNCLAEEEESRKGNLQRAVSVSCMSEFQRLMDVSPFLPEKGLPSAGSKEDVTPPLSPDDLKYIEEFHSNDWDYASPRAEADRPPDPWADRTEMGRVGHEATTEPCPDPSWYLTTSVTMTTDTMTSPEHCQKQPLRTHVLTEQSGVHVLHSPPAIRRVDSIASGGEGRSRADPEGPFPMSRARGNLADAKGGHPEPVLNRWPCTPPRHPRDCVEGSLRPLDRPICPSLGFASPLNSLDMSKNMSDDMKEVAFSVRNAICAGPAEPHVRDMACQTNGSRTAGTQTIQTISVGLQTEALRASGVTSSPHKCLTPKAGGGTTPVSSPSRSLRSRQVAPAIEKVQAKFERTCCSPKYGSPKLQRKPLSKADQPNSRTSPGIPQKGFSESAWARSTTTRESPVHTTINDGLSSLFNIIDHSPIGVRAGSRSRSAEPRQELGPGQETGTSSRGRSPSPLGVGSETFREEGGESTPVRQDLSAPPGYTLTENVARILNKKLLEHALKEERKQASHGSSGLTSDSHTGEPVPAEPGSMEELPCSALAPSLEPCFSRPERPANRRLPSRWAPPSPTASQSQSPGHPMSMEEHGEEDPPEEKPHL
What is the function of this protein?
Microtubule-associated factor involved in the late phase of epithelial polarization and microtubule dynamics regulation.  Plays a role in the development and maintenance of non-centrosomal microtubule bundles at the lateral membrane in polarized epithelial cells.
What are the official names of this protein?
Microtubule cross-linking factor 1, Coiled-coil domain-containing protein 165, PAR-1-interacting protein, SOGA family member 2.
What is the protein family that this protein belongs to?
Belongs to the SOGA family.
What are the subcellular locations of this protein?
[Isoform 1]: Lateral cell membrane. Apical cell membrane. Cytoplasm, cytoskeleton, spindle pole. Midbody. Cytoplasm, cytoskeleton. Note=Colocalized with microtubules at the base of cilia. Gradually accumulates on the apicobasal microtubule bundles during epithelial cell polarization (By similarity). Colocalized with the apicobasal microtubule bundles running beneath the lateral membrane. Colocalized with microtubule bundles in the spindle pole in mitotic cells and in the midbodies at the end of cytokinesis.
Protein: RHAA_OCEIH
Sequence: MDVKQNYEQAKKQYEKWGVNVEDALEKLKQIPISIHCWQGDDVTGFEVNQQELSGGIDVTGNYPGKATTPEELRDDLDKALSLIPGMHRVNLHAIYAETNGEAVERDEIEPKHFENWVKWAKENGLGLDFNPTLFSHPKADDGLTLAHPNKEIRDFWIRHTIASRKIAAYMGKELGTSALTNIWTPDGYKDIPSDRLTPRKRLEDSLNQIFEEEIDKEYNVDAVESKLFGIGSEAYVVGSHEFYMGYALKNNKLCLLDTGHYHPTEMVSNKISSMLLYSDELALHVSRPVRWDSDHVVILDDELREIGLEIVRNDALDKVRIGLDFFDASINRIAAWTIGTRNMIKSLLYALLTPNEHLKQLQEEGNFTDRLAIMEELKTYPFGAIWDYYCESMNVPVGESWLTEVKEYEKEVLSKR
What is the function of this protein?
Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
What are the official names of this protein?
L-rhamnose isomerase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDM3A_HUMAN
Sequence: MVLTLGESWPVLVGRRFLSLSAADGSDGSHDSWDVERVAEWPWLSGTIRAVSHTDVTKKDLKVCVEFDGESWRKRRWIEVYSLLRRAFLVEHNLVLAERKSPEISERIVQWPAITYKPLLDKAGLGSITSVRFLGDQQRVFLSKDLLKPIQDVNSLRLSLTDNQIVSKEFQALIVKHLDESHLLKGDKNLVGSEVKIYSLDPSTQWFSATVINGNPASKTLQVNCEEIPALKIVDPSLIHVEVVHDNLVTCGNSARIGAVKRKSSENNGTLVSKQAKSCSEASPSMCPVQSVPTTVFKEILLGCTAATPPSKDPRQQSTPQAANSPPNLGAKIPQGCHKQSLPEEISSCLNTKSEALRTKPDVCKAGLLSKSSQIGTGDLKILTEPKGSCTQPKTNTDQENRLESVPQALTGLPKECLPTKASSKAELEIANPPELQKHLEHAPSPSDVSNAPEVKAGVNSDSPNNCSGKKVEPSALACRSQNLKESSVKVDNESCCSRSNNKIQNAPSRKSVLTDPAKLKKLQQSGEAFVQDDSCVNIVAQLPKCRECRLDSLRKDKEQQKDSPVFCRFFHFRRLQFNKHGVLRVEGFLTPNKYDNEAIGLWLPLTKNVVGIDLDTAKYILANIGDHFCQMVISEKEAMSTIEPHRQVAWKRAVKGVREMCDVCDTTIFNLHWVCPRCGFGVCVDCYRMKRKNCQQGAAYKTFSWLKCVKSQIHEPENLMPTQIIPGKALYDVGDIVHSVRAKWGIKANCPCSNRQFKLFSKPASKEDLKQTSLAGEKPTLGAVLQQNPSVLEPAAVGGEAASKPAGSMKPACPASTSPLNWLADLTSGNVNKENKEKQPTMPILKNEIKCLPPLPPLSKSSTVLHTFNSTILTPVSNNNSGFLRNLLNSSTGKTENGLKNTPKILDDIFASLVQNKTTSDLSKRPQGLTIKPSILGFDTPHYWLCDNRLLCLQDPNNKSNWNVFRECWKQGQPVMVSGVHHKLNSELWKPESFRKEFGEQEVDLVNCRTNEIITGATVGDFWDGFEDVPNRLKNEKEPMVLKLKDWPPGEDFRDMMPSRFDDLMANIPLPEYTRRDGKLNLASRLPNYFVRPDLGPKMYNAYGLITPEDRKYGTTNLHLDVSDAANVMVYVGIPKGQCEQEEEVLKTIQDGDSDELTIKRFIEGKEKPGALWHIYAAKDTEKIREFLKKVSEEQGQENPADHDPIHDQSWYLDRSLRKRLHQEYGVQGWAIVQFLGDVVFIPAGAPHQVHNLYSCIKVAEDFVSPEHVKHCFWLTQEFRYLSQTHTNHEDKLQVKNVIYHAVKDAVAMLKASESSFGKP
What is the function of this protein?
Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code.  Preferentially demethylates mono- and dimethylated H3 'Lys-9' residue, with a preference for dimethylated residue, while it has weak or no activity on trimethylated H3 'Lys-9'.  Demethylation of Lys residue generates formaldehyde and succinate.  Involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes, resulting in H3 'Lys-9' demethylation and transcriptional activation.  Involved in spermatogenesis by regulating expression of target genes such as PRM1 and TNP1 which are required for packaging and condensation of sperm chromatin.  Involved in obesity resistance through regulation of metabolic genes such as PPARA and UCP1.
What are the official names of this protein?
Lysine-specific demethylase 3A, JmjC domain-containing histone demethylation protein 2A, Jumonji domain-containing protein 1A, [histone H3]-dimethyl-L-lysine(9) demethylase 3A.
What is the protein family that this protein belongs to?
Belongs to the JHDM2 histone demethylase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Nuclear in round spermatids. When spermatids start to elongate, localizes to the cytoplasm where it forms distinct foci which disappear in mature spermatozoa (By similarity).
Protein: ATPG_CHLPM
Sequence: MPTLKDIRVRIKGVTSTQQVTKAMKMVAAAKLRRAQERAVMARPYAAKLSEMLGSLSAKVDTSENPLLSGRSEVRGALVILITSDRGLCGGFNTNIIKVAQRVVNNEYGELNAAGRLSMICAGTRGFDFFRKRGYTILKGYPSVFQNLDFSTAQEIAETASSMYLKGEVDKVVVVYNEFKSVLAPVLKAETLLPISSEENEGDRGGDYIYEPSPSAIISELVPKHLNTQVWRMMLESNAAEQAARMTAMDSATENAKELLRTLNISYNRARQAAITKELSEIVGGADALQN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CCR5_MOUSE
Sequence: MDFQGSVPTYSYDIDYGMSAPCQKINVKQIAAQLLPPLYSLVFIFGFVGNMMVFLILISCKKLKSVTDIYLLNLAISDLLFLLTLPFWAHYAANEWVFGNIMCKVFTGLYHIGYFGGIFFIILLTIDRYLAIVHAVFALKVRTVNFGVITSVVTWAVAVFASLPEIIFTRSQKEGFHYTCSPHFPHTQYHFWKSFQTLKMVILSLILPLLVMVICYSGILHTLFRCRNEKKRHRAVRLIFAIMIVYFLFWTPYNIVLLLTTFQEFFGLNNCSSSNRLDQAMQATETLGMTHCCLNPVIYAFVGEKFRSYLSVFFRKHMVKRFCKRCSIFQQDNPDRASSVYTRSTGEHEVSTGL
What is the function of this protein?
Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level.  May play a role in the control of granulocytic lineage proliferation or differentiation.  Participates in T-lymphocyte migration to the infection site by acting as a chemotactic receptor.
What are the official names of this protein?
C-C chemokine receptor type 5, C-C CKR-5, CC-CKR-5, CCR-5, MIP-1 alpha receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ERA_SHIF8
Sequence: MSIDKSYCGFIAIVGRPNVGKSTLLNKLLGQKISITSRKAQTTRHRIVGIHTEGAYQAIYVDTPGLHMEEKRAINRLMNKAASSSIGDVELVIFVVEGTRWTPDDEMVLNKLREGKAPVILAVNKVDNVQEKADLLPHLQFLASQMNFLDIVPISAETGLNVDTIAAIVRKHLPEATHHFPEDYITDCSQRFMASEIIREKLMRFLGAELPYSVTVEIERFVSNERGGYDINGLILVEREGQKKMVIGNKGAKIKTIGIEARKDMQEMFEAPVHLELWVKVKSGWADDERALRSLGYVDDL
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: RS2_CAMLR
Sequence: MVSMRDLLECGVHFGHQTRRWNPKMKKFIFGERKGIYVIDLQKTLRYFRYTYNIVRDAAAEGKTILFVGTKKQAGGAIKEYAEKCGMPYVNHRWLGGMMTNFGTIRQSIRKLEVIEKMEEDGSIKLLTKKEALMLTRKKEKLLAYLGGIRYMKTQPDMIFVIDTVKEKIAVQEANRLKIPVVAPLDTNCDPDLVDFPIPGNDDAIRSVQLFCQEMAEAINEGKALREQDGEANEEQPISEEEKKEVLEEAMSEEDFEGDKE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: PANB_BACC4
Sequence: MKTKTDFLKMKEQGEPITMLTAYDYPSAKLAEEAEVDMILVGDSLGMVVLGYDSTVPVTVEDMIHHTKAVRRGAKETFIVTDMPFMSYHVSLQETMVNARRIVQESGAHALKVEGAGEVISTIQYLTNAGIPVVAHLGLTPQSVGVLGGYKVQGKDAESAKKLIEDAKKCEEAGAIALVLECVPMQLAELISEQLTIPTIGIGAGQKVDGQVLVYHDLISYGVNRVPKFVKQYTSVQEEIVRGISQYVTEVKTRQFPEEKHSFTMKEEECLVLYGGKQ
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NS1_INBSJ
Sequence: MADNMTTTQIEVGPGATNATINFEAGILECYERLSWQRALDYPGQDRLNRLKRKLESRIKTHNKSEPESKRMSLEERKAIGVKMMKVLLFMNPSAGIEGFEPYCMKNSSNSNCPNCNWTDYPPTPGKCLDDIEEEPENVDDPTEIVLRDMNNKDARQKIKEEVNTQKEGKFRLTIKRDIRNVLSLRVLVNGTFLKHPNGYKSLSTLHRLNAYDQSGRLVAKLVATDDLTVEDEEDGHRILNSLFERFNEGHSKPIRAAETAVGVLSQFGQEHRLSPEEGDN
What is the function of this protein?
Binds and inhibits the conjugation of the ubiquitin-like G1P2/ISG15 protein to its target proteins.  Since G1P2/ISG15 is an early antiviral protein, NS1 may inhibit the host antiviral response.  Prevents EIF2AK2/PKR activation, either by binding double strand RNA or by interacting directly with EIF2AK2/PKR.  Also binds poly(A) and U6 snRNA.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza B viruses NS1 family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: MTNA_NEUCR
Sequence: MSALEAIKYSRGKLEVLDQLRLPHEHHYDEVSTSEEAFDCIKAMRVRGAPAIAIVAALAASVELHNGSCTATGTEDVIKYIDSRLDYLYESRPTAVDLGNAVRLLKKTVRGVKTEGLTDAEAKEAIIKAFIEASEEILAKDLKTNKSIGAFGAKWLQEQYKITDDSKITVMTHCNTGSLATSGHGTALGIIRTLRDEGLLRHAYCTETRPYNQGSRLTAFELVHEGIPATLVTDSMAAALFRLRKAEENIAAVIVGADRVVRNGDTANKIGTYQLAVLAKHHGIKFMVAAPTTSIDVDTETGDDIEIEQRKREELTQISGAVVNADGSIDTSKSVRVAIADQRIGVWNPGFDVTPHEYIDAIVTEKGTVVKGEDGKFHFEDLMPERFQ
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase, Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y1156_FRASN
Sequence: MRVSQRLGRFGEDVAARHLSADGAEILARNWRCRDGEIDIVARHGDTLVFCEVKTRSGADYGSGPDAVVGRKAARIRRLAVRWLAEHPHPPAIIRFDVLSVYRERQGSVRVEHRRGAF
What are the official names of this protein?
UPF0102 protein Franean1_1156.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: ACCD_BACC1
Sequence: MLRDLFVKKKKYAAIPSEQVRKDVPDGVMTKCPKCKKIMYTKELLKNLKVCVNCGYHHPMNAWERLDSILDEGSFREYDKEMVSLNPLEFPGYEEKLESDRKKTELNEAVVTGEGTIDDMLVVVAVMDSRFRMGSMGSVVGEKIARAVEKAYDLQVPFIIFTASGGARMQEGILSLMQMAKTSVALKKHSNAGGLFISVMTHPTTGGVSASFASLGDYNLAEPGALIGFAGRRVIEQTVREKLPEDFQTAEFLLEHGQLDAVVHRDDMRESLRKILEVHQGGEMAVWQS
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COF_ECOLI
Sequence: MARLAAFDMDGTLLMPDHHLGEKTLSTLARLRERDITLTFATGRHALEMQHILGALSLDAYLITGNGTRVHSLEGELLHRDDLPADVAELVLYQQWDTRASMHIFNDDGWFTGKEIPALLQAFVYSGFRYQIIDVKKMPLGSVTKICFCGDHDDLTRLQIQLYEALGERAHLCFSATDCLEVLPVGCNKGAALTVLTQHLGLSLRDCMAFGDAMNDREMLVSVGSGFIMGNAMPQLRAELPHLPVIGHCRNQAVSHYLTHWLDYPHLPYSPE
What is the function of this protein?
Catalyzes the hydrolysis of 4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5-hydroxymethylpyrimidine phosphate (HMP-P).  Can also hydrolyze other substrates such as MeO-HMP-PP and 4-amino-2-trifluoromethyl 5-hydroxymethylpyrimidine pyrophosphate (CF3-HMP-PP) to give MeO-HMP-P and 4-amino-2-trifluoromethyl-5-hydroxymethylpyrimidine phosphate.  This hydrolysis generates resistance to the antibiotics (bacimethrin, CF3-HMP) by reducing the formation of their toxic forms, 2'-methoxythiamin pyrophosphate (MeO-TPP) and CF3-HMP-PP.  Also hydrolyzes pyridoxal-phosphate (PLP) and flavin mononucleotide (FMN), and purines (GMP and IMP) as secondary substrates.
What are the official names of this protein?
HMP-PP phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. Cof family.
Protein: C3H56_ARATH
Sequence: MCGLAKKLDIEDTLTSLSDQENESLAKPMNDAAEWEHSFSALLEFAADNDVEGFRRQLSDVSCINQMGLWYRRQRFVRRMVLEQRTPLMVASLYGSLDVVKFILSFPEAELNLSCGPDKSTALHCAASGASVNSLDVVKLLLSVGADPNIPDAHGNRPVDVLVVSPHAPGLRTILEEILKKDEIISEDLHASSSSLGSSFRSLSSSPDNGSSLLSLDSVSSPTKPHGTDVTFASEKKEYPIDPSLPDIKSGIYSTDEFRMFSFKIRPCSRAYSHDWTECPFAHPGENARRRDPRKFHYTCVPCPDFKKGSCKQGDMCEYAHGVFECWLHPAQYRTRLCKDGMGCNRRVCFFAHANEELRPLYPSTGSGLPSPRASSAVSASTMDMASVLNMLPGSPSAAQHSFTPPISPSGNGSMPHSSMGWPQQNIPALNLPGSNIQLSRLRSSLNARDIPSEQLSMLHEFEMQRQLAGDMHSPRFMNHSARPKTLNPSNLEELFSAEVASPRFSDQLAVSSVLSPSHKSALLNQLQNNKQSMLSPIKTNLMSSPKNVEQHSLLQQASSPRGGEPISPMNARMKQQLHSRSLSSRDFGSSLPRDLMPTDSGSPLSPWSSWDQTHGSKVDWSVQSDELGRLRKSHSLANNPNREADVSWAQQMLKDSSSPRNGNRVVNMNGARPLTQGGSSVNPHNSDTRESDILDAWLEQLHLDR
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 56, AtC3H56.
Protein: MRNC_KOSOT
Sequence: MSDFENFFRTDIVPEELSIDSLSFVGDAVYSLYFRIKTLRSAKRRTGYQHNLTLLYVEAKGQRKALEVIEKFLSEEERIIVRRGYNSRGARKRGDDENYKCATALEALVGYLFLKGRYRRLEELLEKVENDVSSWKKCAERDSKT
What is the function of this protein?
Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor.  Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.
What are the official names of this protein?
Mini-ribonuclease 3, Mini-3, Mini-RNase 3, Mini-RNase III, Mini-III.
What is the protein family that this protein belongs to?
Belongs to the MrnC RNase family.
What are the subcellular locations of this protein?
Cytoplasm.