PharMolix/UniProtQA huggingface dataset:
Protein: RL14_BACSU
Sequence: MIQQETRLKVADNSGAREVLTIKVLGGSGRKTANIGDVIVCTVKQATPGGVVKKGEVVKAVIVRTKSGARRSDGSYISFDENACVIIRDDKSPRGTRIFGPVARELRENNFMKIVSLAPEVI
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: PNP_CHLL2
Sequence: MISMIINKAIDLGQGKIISIETGKMAKQADGSVVVRLGDTMVLATVVSSKKTPPPNQDYFPLQVEYREKYSAAGKFPGGFFKRESRPSEKEILSARLIDRALRPLFPDGYLFETQIIVTVISSDQINDADVLGGLAASAAIMVSDIPFHNAMSEVRVGRINGKFIINPDVNELVNSDLDICIGGTTDTICMLEGEMKEISEAEMLDAIKFGHDAIRRLCALQNEIAAEVAKPARPFAPAVIPSELTDLVRGLCETRLRELAYTPLRKEDRAEQTAAIYREIIQSTVEHFKAAISPEEIQADPSKALCLNEHIIDEQIHAVEKKVMRHMILDDAKRLDGRTLEEVRPISIELGIIPRAHGSALFTRGETQALVTITLGTKKDAQSVDNLTNNADKKFMLHYNFPPFSVGETGRIGSTGRREIGHGNLAERAIKMVAPPEQEFPYTVRIVSDILESNGSSSMASVCGGTLALMDGGVPIRKPVSGIAMGLIKEGSNYAVLSDILGNEDHLGDMDFKVSGTRDGITACQMDIKIDGLDYHILESALEQARRGRLHILDKMEEAIPSARVELAQFAPRLTTIQVPVDAIGLIIGKGGETIRSITEETGAEINIEDDGTVTIACSSVEGTHAALATIKTLLAKPEVGTIYLGKVRDVRDELGAFVEFLPKTDGLVHISEISATERVAKVSDHLKIGDRIKVKLVDVRKDPRTGKTRFALSMRAVETDAANGAPQENNQENQ
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 1104L_ASFK5
Sequence: MLVIFLGILGLLANQVLGLPTQAGGHLRSTDNPPEEELKYWCTYMESCKFCWECTHGLCKNKVNESMPTIIENSYLTSCEVSRWYNQCTYDEGNGHYHVMDCSDPVPHNRPHRLRMKIYKKEDL
What is the function of this protein?
Causes the redistribution of lumenal ER protein to an enlarged ERGIC compartment.
What are the official names of this protein?
Protein MGF 110-4L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 110 family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum-Golgi intermediate compartment.
Protein: PTMCB_STAAC
Sequence: MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKTTSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II CmtAB PTS system is involved in D-mannitol transport.
What are the official names of this protein?
PTS system mannitol-specific EIICB component, EIICB-Mtl, EII-Mtl.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CLPS_BURMA
Sequence: MAIIPDKQDSSVLERKEQKLKPPSMYKVVLLNDDFTPMEFVVMVVQEYFKKDRETATQIMLKVHREGRGVCGVYTRDIASTKVEQVVTHARQAGHPLQCVMEEA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: RUVC_ACAM1
Sequence: MTKKILGLDPGLASLGFGVICTESDNLELLDFGIIQTPAKTDIGKRLQIIYEDLHQVLNTHQPDVVAIEKLFFYRMGNTILVAQARGVVLLVLAQHQLPIIEYTPAQIKLALTGYGAADKVAVQEAVARELCLDCLPRPDDAADALAVALTAWFQR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: TFE_SULIY
Sequence: MVNAEDLFINLAKSLLGDDVIDVLRVLLEKGTEMTDEEIANQLNIKVNDVRKKLNLLEEQGFVSYRKTRDKDSGWFIYYWKPNIDQINEILLNRKRLILDKLKSRLEYEKNNTFFICPQDNSRYSFEEAFENEFKCLKCGSQLTYYDTEKIKSFLEQKIRQIEEEIDKETKLGANKSH
What is the function of this protein?
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase.  Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment.  Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal.  It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes.  Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
What are the official names of this protein?
Transcription factor E, TFE, TFIIE subunit alpha homolog, Transcription initiation factor TFIIE.
What is the protein family that this protein belongs to?
Belongs to the TFE family.
Protein: Y3924_AZOC5
Sequence: MTDHECEIRSVDGSWEAVGVEEALGLPSSLLKRCPECHGRVRVHRASVNGMRAHFEHMEAHRGCSLSRGVQFSGVSSPHPAALD
What are the official names of this protein?
Uncharacterized protein AZC_3924, ORF3.
Protein: PETD_PROMT
Sequence: MSTLKKPDLTDTKLRAKLAKGMGHNYYGEPAWPNDLLYIFPVVILGTIACVVGLAVLDPAFLGDKANPFATPLEILPEWYLYPVFQILRVVPNKLLGIALQTLIPLGLMILPFIENINKFANPFRRPVAMSLFLFGTVLTMYLGIGACLPIDKSLTLGLF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 4, 17 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetD subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: LIPA_SALHS
Sequence: MSKPIVMERGVKYRDADKMALIPVKNVVTERDALLRKPEWMKIKLPADSTRIQGIKAAMRKNGLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPFCDVAHGRPVAPDAEEPQKLAQTIADMALRYVVITSVDRDDLRDGGAQHFADCITAIRAKSPEIKIETLVPDFRGRMDRALDILNATPPDVFNHNLENVPRIYRQVRPGADYNWSLKLLERFKEAHPEIPTKSGLMVGLGETNAEIIEVMRDLRRHGVTMLTLGQYLQPSRHHLPVQRYVSPEEFDEMKAEALAMGFTHAACGPFVRSSYHADLQAKGMEVK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SC61B_CHLRE
Sequence: MAGSQSQASTLVARGGRSSSNAPTGAAGALRRRPVRGSGGSGTTKAQQAAMNFYTDDTPGWKMSPVVVITMSLSFIAFVTILHVVGKFQ
What is the function of this protein?
Necessary for protein translocation in the endoplasmic reticulum.
What are the official names of this protein?
Protein transport protein Sec61 subunit beta.
What is the protein family that this protein belongs to?
Belongs to the SEC61-beta family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: G1PDH_METBF
Sequence: MKLTINKNSAKWMQLPRDVLVGHGVLEEIGDVCRDLKMKGNALIVTGSTTNNIAGKRVSNLLESAGCSAEMVLTCKATKEEVEKVMEKALEVETNFLIGVGSGRSIDLAKLASTRLELPFISVPTAASHDGIASSRASIVDNGRSTSAQAQAPIAVIADTEIISAAPFRFLAAGCGDIISNYTAVLDWELASRLRNEYFGAYAAALSRMAARVIIECADSIKPEHETSARLVVKALVSNGVAMSIAGSSRPASGSEHMFSHALDKIAPKPALHGEQCGVGTIMMMYLHGGNWQEIREALKKIGAPVTAEELGIEDRYIIEALLHAHSIRPERYTILGSGLNPSAAEKVARITKVIN
What is the function of this protein?
Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P).  The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
What are the official names of this protein?
Glycerol-1-phosphate dehydrogenase [NAD(P)+], G1P dehydrogenase, G1PDH, Enantiomeric glycerophosphate synthase, sn-glycerol-1-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glycerol-1-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_ACTP2
Sequence: MRTSQYLFSTLKETPNDAQVVSHQLMLRAGMIRPMASGLYNWLPTGIKVLKKVENIIREEMNKGGAIEVLMPVVQPAELWQESGRWNDYGAELLRFVDRGSRDFVLGPTHEEVITDLVRREVSSYKQLPLNLYQIQTKFRDEVRPRFGVMRSREFVMKDAYSFHVDKASLQETYDVMYQVYSNIFTRLGLDFRAVQADTGSIGGSASHEFQVLASSGEDDVVFSTESDFAANIELAEAVAVGERQAPTAEMQLVDTPNAKTINELVEQFNLPIGKTVKTLIVKGATEEQPLVALVLRGDHELNEIKAQKHPLVADPLEFADEAEIKAKIGAGVGSLGVINLNVPAIIDRSVAVMSDFGCGANIDGKHYFNVNWERDAAMPEVADLRNVVEGDPSPDGKGVLQIKRGIEVGHIFQLGTKYSEAMKATVQGEDGKPLVMTMGCYGIGVTRVVAAAIEQHHDERGIIWPSDEIAPFTVAIVPMNMHKSESVQQFSEELYRTLKAQGVDVIFDDRKERPGVMFADMELIGVPHMVVIGEKNLANGEIEYKNRRTGEKQMIAKDQLLAFLKENVKA
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIPT3_RAT
Sequence: MNAAVVRRTQEALGKVIRRPPLTEKLLNKPPFRYLHDIITEVIRITGFMKGLYTDAEMKSDNVKDKDAKISFLQKAIDVVMMVSGEPLAAKPARIVAGHEPERTNELLQLIGKCCLSKLSSDEAVKRVLAGEKGDSRGRVLRTSKAQEPDNKSVKEEESRTQKEEKRSSEVKERSSSAEHKQKEELKEDSKPREKERDKEKAKEADRDRHREPDRDRNRDGEREKARARAKQDRDRNNKDRDRETERDRDRDRRSDGGKEKERQKDRDRDKGKDRERRKSKNGEHTRDPDREKSRDADKSEKKADISVGASKSSTLKASKRRSKNSLEGRKEDNISAKILDSIVSGLNDEPDQETTAPEIDDNSASLWRENAEPEPAVKQKGDSPSDAEGEAVPTSQDKLEVTENAEVSNELPSSLRRIPRPGSARPAPPRVKRQESTETLAGDRSGSGKTVSTVIIDSQNSDNEDDEQFVVEAAPQLSEIAEIEMVPSGDLEDEEKHGGLVKKILETKKDYEKLQQSPKPGEKERSLIFESAWKKEKDIVSKEIEKLRVSIQTLCKSALPLGKIMDYIQEDVDAMQNELQLWHSENRQHAEALSKEQSITDSAVEPLKAELSELEQQIKDQQDKICAVKANILKNEEKIQKMVHSINLSSRR
What is the function of this protein?
Plays an inhibitory role on IL13 signaling by binding to IL13RA1.  Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding.  Recruits TRAF3 and DISC1 to the microtubules (By similarity).  Involved in kidney development and epithelial morphogenesis.  Involved in the regulation of microtubule cytoskeleton organization.  Is a negative regulator of microtubule stability, acting through the control of MAP4 levels.  Involved in ciliogenesis (By similarity).
What are the official names of this protein?
TRAF3-interacting protein 1, Intraflagellar transport protein 54 homolog, Microtubule-interacting protein associated with TRAF3, MIP-T3.
What is the protein family that this protein belongs to?
Belongs to the TRAF3IP1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, cilium. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, cilium basal body. Note=Microtubules. In the cilium, it is observed at the ciliary base, ciliary transition zone and ciliary tip.
Protein: SEN54_ASHGO
Sequence: MTEAEELSVALGLHDSDAEEDALAQDWSEMAKLVKKANQHALPRRGEKDYEPDGTDAQALLLHTAKETMFGTLLNSVRGSTVKTLIKAYWEEEQRMARIPNARGSFTNTMGKVDKHGQCWLQLHEFVYLVERGTVSPYLALTVGDEKSNHEDVLLSVQDVYALFSSTEELDEFLVYAHLKRLGFIVVSTDNPPAHVTSFYPPLSQKSSASSNWFCHIHSWLKTPQNLFHVPLYHPLHFLLHRYTSSPQLYEELSQHIPFKKVPHDINELREERNNGILNPNVKQWKIAFNVWKPKSSFKKKTPGLPDFQVVVYNKDNAGQQFPTYDEFRSIFHRLDYRFDFLNELDVDDSAWDDYTYTDGMPTREFMQRNKIAPSQPHSGGDSRKKKARTYPQHIAQIRRLKSGFKSFILSVIDDGLVSFVRIAESDFGSSNIWYTPPSQTGTTNNRTRSDKVDV
What is the function of this protein?
Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA.  It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron.  The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini.  There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.  May be required to embody the molecular ruler of the complex (By similarity).
What are the official names of this protein?
tRNA-splicing endonuclease subunit SEN54, tRNA-intron endonuclease SEN54.
What is the protein family that this protein belongs to?
Belongs to the SEN54 family.
Protein: NUOC_MYCBP
Sequence: MSPPNQDAQEGRPDSPTAEVVDVRRGMFGVSGTGDTSGYGRLVRQVVLPGSSPRPYGGYFDDIVDRLAEALRHERVEFEDAVEKVVVYRDELTLHVRRDLLPRVAQRLRDEPELRFELCLGVSGVHYPHETGRELHAVYPLQSITHNRRLRLEVSAPDSDPHIPSLFAIYPTNDWHERETYDFFGIIFDGHPALTRIEMPDDWQGHPQRKDYPLGGIPVEYKGAQIPPPDERRGYN
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SMP90_STOME
Sequence: NLDTPYCFYSGDYGG
What is the function of this protein?
Has strong superoxide anion radical-scavenging activity (EC(50)~16 ug/mL).
What are the official names of this protein?
Antioxidant protein SmP90.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: GCSH_RABIT
Sequence: MALRVVRSLRAAACSLFAASAPAAPCSPLPWRLRAGAVRTLRTGPALLSVRKFTEKHEWITTENGIGTVGISNFAQEALGDVVYCSLPEVGTKLKKQDEFGALESVKAASELYSPLSGEVTEINEALAENPGLVNKSCYEDGWLIKMTLSNPSELDELMSEEAYEKYIKSIEE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST) (By similarity).
What are the official names of this protein?
Glycine cleavage system H protein, mitochondrial, Lipoic acid-containing protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: WUS_ARATH
Sequence: MEPPQHQHHHHQADQESGNNNNNKSGSGGYTCRQTSTRWTPTTEQIKILKELYYNNAIRSPTADQIQKITARLRQFGKIEGKNVFYWFQNHKARERQKKRFNGTNMTTPSSSPNSVMMAANDHYHPLLHHHHGVPMQRPANSVNVKLNQDHHLYHHNKPYPSFNNGNLNHASSGTECGVVNASNGYMSSHVYGSMEQDCSMNYNNVGGGWANMDHHYSSAPYNFFDRAKPLFGLEGHQEEEECGGDAYLEHRRTLPLFPMHGEDHINGGSGAIWKYGQSEVRPCASLELRLN
What is the function of this protein?
Transcription factor that plays a central role during early embryogenesis, oogenesis and flowering, probably by regulating expression of specific genes.  Required to specify stem cell identity in meristems, such as shoot apical meristem (SAM).  May induce shoot stem cells activity in order to maintain the stem cell identity.  Involved in the developmental root meristem.  In shoot apices, it is sufficient to induce the expression of CLV3, a putative ligand of the CLV signaling pathway.  Also required to sustain organogenesis in the floral meristem by contributing to the expression of its own repressor, the AGAMOUS (AG) gene at the end of flower development.  Binds directly to the 5'-TTAAT[GC][GC]-3' DNA sequence in the regulatory sequence of AG and activates its expression directly.  Regulates one important step in ovule development to induce integument formation from the underlying chalazal domain.  Participates in the promotion of vegetative to embryonic transition.  Required to repress LEC1 expression.
What are the official names of this protein?
Protein WUSCHEL, AtWUS, Plant growth activator 6.
What is the protein family that this protein belongs to?
Belongs to the WUS homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: IPTZ_AGRT7
Sequence: MILHLIYGPTCSGKTDMAIQIAQETGWPVVALDRVQCCPQIATGSGRPLESELQSTRRIYLDSRPLTEGILDAESAHRRLIFEVDWRKSEDGLILEGGSISLLNCMAKSPFWRSGFQWHVKRLRLGDSDAFLTRAKQRVAEMFAIREDRPSLLEELAELWNYPAARPILEDIDGYRCAIRFARKHDLAISQLPNIDAGRHVELIEAIANEYLEHALSQERDFPQWPEDGAGQPVCPVTLTRIR
What is the function of this protein?
Transfers dimethylallyl groups to AMP as part of the biosynthesis of cytokinin phytohormones.
What are the official names of this protein?
Adenylate dimethylallyltransferase, Dimethylallyl transferase, Isopentenyl transferase, Trans-zeatin producing protein.
Protein: IMA3_CAEEL
Sequence: MSSNRQAYYKNNAKEQIGKEKRNEEVVSIRKDKREEAISKRRNINTQIEDDSETSTTPPGPFDANLLRLTVAAAQSSDPAEQLTAVQQARKMLSTDRNPPIDDLIGSGILPVLVQCLSSTDPNLQFEAAWALTNIASGTSEQTQAVVNAGAVPLFLQLLSCGNLNVCEQSVWALGNIIGDGPHFRDYCLELGILQPLLQFINPEIPIGFLRNVTWVIVNLCRCKDPAPSPAVVRTILPALSLLIHHQDTNILIDTVWALSYLTDGGNEHIQMVIEAQVVTHLVPLLGHVDVKVQTAALRAVGNIVTGTDEQTQLVLDSGVLRFMPGLLAHYKEKINKEAVWFVSNITAGNQQQVQDVFDAGIMPMIIHLLDRGDFPTQKEAAWAISNVTISGRPNQVEQMVKLGVLRPFCAMLSCTDSQIIQVVLDGINNILKMAGEAAEQVTSEIEECGGLDKIENLQNHENEDIYKLAFEIIDNFFSSDDETGNVEGAQSSAFGGDVPPVPDAPNGGWNFGK
What is the function of this protein?
Binds specifically and directly to substrates containing either a simple or bipartite NLS motif (PubMed:11311162).  Promotes docking of import substrates to the nuclear envelope (PubMed:11311162).  Seems to act as a cytosolic receptor for both simple and bipartite NLS motifs (PubMed:11311162).  Necessary for correct nucleoporin localization within the germline (PubMed:11311162).  Essential gene for embryonic and larval development (PubMed:11311162).  May be dispensable for axon development, but required for axon regeneration in both mechanosensory and motor neurons (PubMed:31417366).  Required for oogenic development, ima-1 and ima-2 cannot functionally compensate for loss of ima-3 (PubMed:11311162).
What are the official names of this protein?
Importin subunit alpha-3, Karyopherin subunit alpha-3.
What is the protein family that this protein belongs to?
Belongs to the importin alpha family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DSBD_SODGM
Sequence: MAQRRFTLILLACLTCLPLLPAHAALFGNSHGNQFIPAEQAFRFDFRQQGSQLTLSWDIHPGYYLYRQQIRLEPVNATLGAFTLPAGSRHHDEFYGDDVAIYRDELNITLPLAQAQNDSQLRVTWQGCAEAGFCYPPETQVIPLSAIAAAPPSGTGIGSTALIPAPPPAGGQGIITPAPPPQSNNLPFSPLWALLIGIGIAFTPCVLPMYPLISAVILGNRLQLSTARVLLLAVVYVMGMAITYTLLGVAVAAAGLQFQAVLQQPALLIGLAALFILLALSMFGVFTLQLPSALQTHLALWSNRQRQGTLPGVFIMGALAGLFCSPCTTAPLSAILLYIAQSGNLWFSGFTLWLYAVGMGIPLILVALFGHRLLPKRGPWMQQVKQGFGFVILALPVFLLERVLGDSWGTRLWSLLGVAFFGWGFLLCLQARWRGARWLAVLMLGLTLISARPLQDWLWGAPADMTSTTGAAPVFQPVQTLAQITQALNAAPGKPVMLDLYADWCVACKEFDKYTFRDPAVVEQMSRFTLLQADVTANAPVQRMLLGQLQVIGLPTILFFDSRGHEIPGSRLTGYMNAADFTRHLRKLAP
What is the function of this protein?
Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes.  Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm.  This transfer involves a cascade of disulfide bond formation and reduction steps.
What are the official names of this protein?
Thiol:disulfide interchange protein DsbD, Protein-disulfide reductase, Disulfide reductase.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. DsbD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RPIA_VIBVU
Sequence: MTQDEMKKAAGWAALKYVEKGSIVGVGTGSTVNHFIDALGTMSEEIKGAVSSSVASTEKLEALGIKIFDCNEVASLDIYVDGADEINADREMIKGGGAALTREKIVAAIADKFICIVDGTKAVDVLGTFPLPVEVIPMARSYVARQLVKLGGDPCYREGVITDNGNVILDVYGMKITNPKQLEDQINGIPGVVTVGLFAHRGADVVITGTPEGAKIEE
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: RMF_CELJU
Sequence: MKRQKRDQTERAFVKGYQAGIEGRSKSLCPHESGLARQQWLNGWRESRMDQWDGYSRLAQVQKITNLHPMSMSG
What is the function of this protein?
During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes).
What are the official names of this protein?
Ribosome modulation factor, RMF.
What is the protein family that this protein belongs to?
Belongs to the ribosome modulation factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPK_STRPI
Sequence: MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAGWVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAIVWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGELLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEVRSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNTGEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYARDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDIIDTMQMDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGLSVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.