PharMolix/UniProtQA huggingface dataset:
Protein: ARGC_LISW6
Sequence: MKVSIIGATGYSGLELIRLIQQHSSVDIATLHSFSNQTNLLSNLYPHLKNLEASPLEKINPKDIIEKSETVFLATPSGISKDIALPYIDAGLNVIDLSGDFRLKNSQLYEKWYEKSAPLENYLMRAEYGLAEFRENKESTFIANPGCYATATLLGLAPLVKKQLIEPTSIIVDAKSGISGAGKVPSTSTHFTETNENMTLYKMNSHQHIPEIMQQLTKWDESIPAIQFSTSLIPITRGIFTTIYVRPKKPIAWEELHKLYESTYENAPFVRIQKENVYPTVKQVTASNYCDIGLAYNEITNVITIVSVIDNLVKGAAGQAIQNLNIMANFAENDGLGFIPVYP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSRA_CLOK5
Sequence: MLVISRKKGESLLIGEDIEITVTKIEEGAVKLSISAPRSVTILRKELYREIEEENKNSAASDISVLKKLKGKK
What is the function of this protein?
A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation.  Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
What are the official names of this protein?
Translational regulator CsrA.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_HYOLA
Sequence: MRINPTTSSPVVSTLEEKNLGRIAQIIGPVLDVVFPPGKMPNIYNALVVKGRDTVGQQINVTCEVQQLLGNNRVRAVAMSATDGLMRGMEVIDTGAPLSVPVGGATLGRIFNVLGEPVDNLGPVDTRTTSPIHRSAPAFIQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEKNIAESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRVLAAKGIYPAVDPLDSTSTMLQPRIVGEEHYETAQRVKQTSQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFQLILSGELDGLPEQAFYLVGNIDEATAKAMNLEVESKLNK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: COMD5_RAT
Sequence: MSALGAAAPYLHHPADSHSGRVSFLGSQPSPEVTAVAQLLKDLDRSTFRKLLKLVVGALHGKDCREAVEQLGASANLSEERLAVLLAGTHTLLQQALRLPPASLKPDAFQEELQELGIPQDLIGDLASLAFGSQRPLLDSVAQQQGSSLPHVSYFRWRVDVAISTSAQSRSLQPSVLMQLKLTDGSAHRFEVPIAKFQELRYSVALVLKEMAELEKKCERKLQD
What is the function of this protein?
May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (By similarity).  Negatively regulates cell proliferation.  Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway (PubMed:12620924).  Involved in kidney proximal tubule morphogenesis (PubMed:24515317).  Down-regulates activation of NF-kappa-B (By similarity).
What are the official names of this protein?
COMM domain-containing protein 5, Hypertension-related calcium-regulated gene protein, HCaRG.
What are the subcellular locations of this protein?
Nucleus.
Protein: MGRB_ECOBW
Sequence: MKKFRWVVLVVVVLACLLLWAQVFNMMCDQDVQFFSGICAINQFIPW
What is the function of this protein?
PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing.  MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway.  Represses PhoP/PhoQ signaling, possibly by binding to the periplasmic domain of PhoQ, altering its activity and that of downstream effector PhoP.
What are the official names of this protein?
PhoP/PhoQ regulator MgrB.
What is the protein family that this protein belongs to?
Belongs to the MgrB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: U13_HHV6U
Sequence: MAHAKKRVRRKLLTSTDDPILSNTFTMRPTSKIADAEIISREHDYIASKTQTDSKKISPLSVILDKTVLFEFYGIGDNNEKAIVYPIDPDFLLCDSEHNCTLSPFL
What are the official names of this protein?
Uncharacterized protein U13.
Protein: Y1944_STAHJ
Sequence: MNIGLALIPSKSFQDEVNGYRKRYDTEYARIMPHITIKSHFEINDDELDSVKEEVKKRLEGFGPVDVHATKASSFKPTNNVIYFKVAKTDELEQLFNLFNTEDFHGEAEHPFVPHFTIAQGLTSQEFEDIFGQVELVGVDLKEKIEELSLLRYDEEEDKWKVIDTFKLA
What are the official names of this protein?
Putative phosphoesterase SH1944.
What is the protein family that this protein belongs to?
Belongs to the 2H phosphoesterase superfamily. YjcG family.
Protein: YEHB_ECOLI
Sequence: MLRMTPLASAIVALLLGIEAYAAEETFDTHFMIGGMKDQQVANIRLDDNQPLPGQYDIDIYVNKQWRGKYEIIVKDNPQETCLSREVIKRLGINSDNFASGKQCLTFEQLVQGGSYTWDIGVFRLDFSVPQAWVEELESGYVPPENWERGINAFYTSYYLSQYYSDYKASGNNKSTYVRFNSGLNLLGWQLHSDASFSKTNNNPGVWKSNTLYLERGFAQLLGTLRVGDMYTSSDIFDSVRFRGVRLFRDMQMLPNSKQNFTPRVQGIAQSNALVTIEQNGFVVYQKEVPPGPFAITDLQLAGGGADLDVSVKEADGSVTTYLVPYAAVPNMLQPGVSKYDLAAGRSHIEGASKQSDFVQAGYQYGFNNLLTLYGGSMVANNYYAFTLGAGWNTRIGAISVDATKSHSKQDNGDVFDGQSYQIAYNKFVSQTSTRFGLAAWRYSSRDYRTFNDHVWANNKDNYRRDENDVYDIADYYQNDFGRKNSFSANMSQSLPEGWGSVSLSTLWRDYWGRSGSSKDYQLSYSNNLRRISYTLAASQAYDENHHEEKRFNIFISIPFDWGDDVSTPRRQIYMSNSTTFDDQGFASNNTGLSGTVGSRDQFNYGVNLSHQHQGNETTAGANLTWNAPVATVNGSYSQSSTYRQAGASVSGGIVAWSGGVNLANRLSETFAVMNAPGIKDAYVNGQKYRTTNRNGVVIYDGMTPYRENHLMLDVSQSDSEAELRGNRKIAAPYRGAVVLVNFDTDQRKPWFIKALRADGQSLTFGYEVNDIHGHNIGVVGQGSQLFIRTNEVPPSVNVAIDKQQGLSCTITFGKEIDESRNYICQ
What is the function of this protein?
Part of the yehABCD fimbrial operon.  Could contribute to adhesion to various surfaces in specific environmental niches.  Probably involved in the export and assembly of fimbrial subunits across the outer membrane.
What are the official names of this protein?
Outer membrane usher protein YehB.
What is the protein family that this protein belongs to?
Belongs to the fimbrial export usher family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: THIC_WIGBR
Sequence: MSSSKKESRNNAKNFIKNFSENLYPNSNRVYLNNSDKSIKVPVRSVELNRTEIIDNNNKIKYEENSPVMIYDTSGPYGDPKSLIDMKSGLNKLRNKWIIDRKDVELISKNLNLENKNNNFKKNIDHYISKKNRCITQLYYAKSGIITKEMEFVSIRENMNYEYSESEAKNNKKITPEFVRKEVASGRAIIPSNINHPESEPMVIGRNFFVKINANIGNSSISSSIEEEVQKLIWSVKWGADTVMDLSTGRNIHETREWILRNSPVPIGTVPIYQALEKANGIVENLNWKIFKKTLLEQAEQGVDYFTIHAGLLLRYIPMTSNRLTGIVSRGGSIIAKWCLFHHKENFIYENFEEICKICSCYDISLSLGDGLRPGSIKDANDEAQFAELYTLGKLTKVAWNYNVQVMIEGPGHVPINMIKENMTKQLKYCHEAPFYTLGPLTTDIAPGYDHFTSGIGAALIGWYGCAMLCYVTPKEHLGLPNKEDVKQGLIAYKIAAHAADIAKGHHISQIRDDAISKARFEFRWEDQFNLSIDPNTARSFHDETLPKSSGKNFHFCSMCGPKFCSMKISQEVRDFAKNKKIIDGMNKMSEIFKKNNNKMSLKK
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: YVKC_BACSU
Sequence: MYSVLFRQAEESSQLAGAKGMNLIKLTKHGLPVPDGFIIQTNALARFMEDNQLQETSENVEGGIISGTFSDELKDELTSSFYKLRESYRSVAVRSSSASEDLEGASFAGQYETYLNIKTEEEFLAKVKECWASFFSGRVSSYKKKMNNQIAEPLMGIVVQGLIDSEMSGVIFSRNPVTHDDRELLISASYGLGEAVVSGNVTPDTFIVNKSSFEIQKEIGAKEIYMESAAEGIAEKETSEDMRSRFCLTDEQVIELAEITKKTEDLYGYPVDIEFGIADHQIYLLQARPITTIDQDKKAAEEKRSFMITDTDMNDFWLNMESNIEGPVSPLFSSFIVPALEYGLKKSMQKFPIGVVVDEVKLYRGHIYSKNQGGQQPPSEDCGKELFPILSEHMYDIINHTYLPFYRTLDQLAQTEHTAESALEAFQKLKAFYLTAYEEHFNIVFPQILLTNKLQAMYQDIQGESENAHFYEMLTGKMNKSLETDRCLWLFSVEVQENPNLLAIFENNKPEQLQEKLEQTDEGRHFLKNVHEFLQEYGWRSVKSHDLIEQIWVENPYFALANIQNYVRNGYHFDNEFQKTKEKREKLYNEFLESIEDPGLRTEFDRYYQWTLNSANIKDDHHFYIDAMLDAKARIFLLKIGELLAENGVIQDREDLWFLYDDEVEQALLHPVSLQEKAEKRRQIFHEYELAQAPAYLGTPTKEQLKAAEEIVGAVIEDEKNTENHIFGIAASSGIATGPVKIIRDANEFSQFAPGDVLVCKMTTPLWTSLFQDAKAIITDTGGILSHAAIIAREYGIPAVLGTRTATERLRDGDIITVDGSSGKITVVSRS
What are the official names of this protein?
Uncharacterized phosphotransferase YvkC.
What is the protein family that this protein belongs to?
Belongs to the PEP-utilizing enzyme family.
Protein: AROC_DEIRA
Sequence: MRYLTAGESHGPQLTAIIEGLPAQLPLGKADIDPWLRKRQGGYGRGRRMVIETDEAELLSGVRAGRTTGAPVTLAIQNKDHRNWTEIMSPEPGGEPRKKALTDARPGHADLTGGIKYRHKDLRDVLERASARETAARVAVGSIALKLLSELGIEGANYVFNLAGIETRQAFSWDALDAIEDSDLRTPDADAAAQMRERIDQAKKDGDTLGGILEVRFRGLPVGLGSFVHYDRKLDGKIAQACLSVQAMKGVEIGRAFENAVKPGSGVHDAIHYREGTYARDTNGAGGLEAGMTNGEELIVRVAMKPIATLMKPLPTVNVVTHEASDAARERSDTTAVPAAGVILQCVIGWVLAEAITEKFGGDTLPELQERLAAARRYAAEY
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: CYC_MELGA
Sequence: MGDIEKGKKIFVQKCSQCHTVEKGGKHKTGPNLHGLFGRKTGQAEGFSYTDANKNKGITWGEDTLMEYLENPKKYIPGTKMIFAGIKKKSERVDLIAYLKDATSK
What is the function of this protein?
Electron carrier protein.  The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase.  Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
What are the official names of this protein?
Cytochrome c.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane.
Protein: PR13A_PLARH
Sequence: MKYIILFLVLIGLQANLALGSKCKCDCTKYPYSPVCAKELKTGDTETFNNVCQLQCYNCTHMKNYVVIYSGSC
What is the function of this protein?
May act as a serine protease inhibitor, since it possess the kazal serine protease inhibitor signature.
What are the official names of this protein?
Kazal peptide Pr13a, Venom Kazal domain peptide Pr13a.
What are the subcellular locations of this protein?
Secreted.
Protein: RS2_SOLUE
Sequence: MPAISMKELLEAGVHFGHQTKRWNPKMKEYIFGERNGIYIIDLQKTLKMFKDAARFVGEMAAQGKNVLFVGTKRQAQEAIAEEANRCQMYYVNQRWLGGLLTNMLTVQKSIKRLKELEAMASVEGGYAGRPKKEVIRLERERKHLDQNLSGIKDMPGLPDVLFVIDSNKEGIAVKEARRLGIPVVAIVDTNCDPDEVDWVIPGNDDALRAIRLFASKIADAVVEGRALATEQDFTADKIISDETPAEEGMMEYTEYVDPKYAEKIMAESLSMAEEPAPPSQRKGPASETAEPVAEPAVTESGS
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RS17_ALISL
Sequence: MSEKIRTMQGRVISDKMDKSIVVAIERMVKHPIYGKYIKRTTKLHAHDENNECGQGDLVVIRECRPLSKTKSWTLVNIVEKAKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: TX329_LYCSI
Sequence: MKFVLLFGVLLVALFSYSSAEMLDDFGQADEDELLSLIEKEEARAKECTPRFYDCSHDRHSCCRSELFKDVCTCFYPEGGDNEVCTCQQPKHLKYMEKAAGKAKKFGGKIKKWFG
What are the official names of this protein?
U3-lycotoxin-Ls1k, Toxin-like structure LSTX-B29.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 01 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PUR2_STAAS
Sequence: MNVLVIGAGGREHALAYKLNQSNLVKQVFAIPGNEAMTPIAEVHTEISESDHQAILDFAKRQNVDWVVIGPEQPLIDGLADILRANGFKVFGPNKQAAQIEGSKLFAKKIMEKYNIPTADYKEVERKKDALTYIENCELPVVVKKDGLAAGKGVIIADTIEAARSAIEIMYGDEEEGTVVFETFLEGEEFSLMTFVNGDLAVPFDCIAQDHKRAFDHDEGPNTGGMGAYCPVPHISDDVLKLTNETIAQPIAKAMLNEGYQFFGVLYIGAILTKNGPKVIEFNARFGDPEAQVLLSRMESDLMQHIIDLDEGKRTEFKWKNESIVGVMLASKGYPDAYEKGHKVSGFDLNENYFVSGLKKQGDTFVTSGGRVILAIGKGDNVQDAQRDAYEKVSQIQSDHLFYRHDIANKALQLK
What are the official names of this protein?
Phosphoribosylamine--glycine ligase, GARS, Glycinamide ribonucleotide synthetase, Phosphoribosylglycinamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the GARS family.
Protein: RSMH_ECOLC
Sequence: MMENYKHTTVLLDEAVNGLNIRPDGIYIDGTFGRGGHSRLILSQLGEEGRLLAIDRDPQAIAVAKTIDDPRFSIIHGPFSALGEYVAERDLIGKIDGILLDLGVSSPQLDDAERGFSFMRDGPLDMRMDPTRGQSAAEWLQTAEEADIAWVLKTYGEERFAKRIARAIVERNREQPMTRTKELAEVVAAATPVKDKFKHPATRTFQAVRIWVNSELEEIEQALKSSLNVLAPGGRLSIISFHSLEDRIVKRFMRENSRGPQVPAGLPMTEEQLKKLGGRQLRALGKLMPGEEEVAENPRARSSVLRIAERTNA
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPTF_HAEIN
Sequence: MILIRYLIKEVFKSQIAILLILLLIFFSQQFVRVLGAAANGNVPADLVFSLLGLGMPTMAQLMLPLCLFIAILLTFGRLYAESEITVMRACGVGQRILVKVALIMSLLTAGIAAYNALWLSPWAIQKQVNMVEDAKANPTVGVLSSGQFISTNNNNVVLFIDKIKDNQIRNVYLFQMTPQKQTKPSVITAEKGELIALPNGDQVLNLKNTKRVEGTSALPDFRITHFDEYHAYLGYQSAENTNDEVAELTLSQLIDLDSSSAKAELHWRITLILAVPLMALIAVPLSRVNPRQGRFAKILPALLLYLIYFLLQSSFKSAGSAGKLEAELLMPLVNIGFFLLAVVLNSWDSEIMYKFRYLFSKKGSAKDDKYP
What is the function of this protein?
Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.
What are the official names of this protein?
Lipopolysaccharide export system permease protein LptF.
What is the protein family that this protein belongs to?
Belongs to the LptF/LptG family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ZAR2A_XENLA
Sequence: MAGFVYSPYNAYQGYGGNFGQNPHRPQAFPKNKQAAWKSNKSSEPPDYLDHFQRAQLKAILSQVNPNLTPRLRKVNTKEMGVQVNPRVDTGVQCSLGPRTLRRPPPPPSSPVKPTDCARFSRPVAVYSPVVDRRLFSLPQGGRLPKKSLPAPDSQSQPLKDRGPSPEEKEPETKEALEKSPVPGAEEPNEEEPNKPAFQFLEQKYGYFHCKDCKTRWESAYVWCISGSNKVYFKQLCRKCQKGFNPYRVEVIQCQVCAKTRCSCPQKKRHIDLKRPHRQELCGRCKNKKLSCDNTYSYKYIV
What is the function of this protein?
mRNA-binding protein required for maternal mRNA storage, translation and degradation during oocyte maturation (PubMed:22732570).  Probably promotes formation of some phase-separated membraneless compartment that stores maternal mRNAs in oocytes: acts by undergoing liquid-liquid phase separation upon binding to maternal mRNAs (By similarity).  Binds to the 3'-UTR of maternal mRNAs, inhibiting their translation (PubMed:22732570).
What are the official names of this protein?
Zygote arrest protein 2.S, Zygote arrest protein 2, Xzar2, Zygote arrest protein 2A.
What is the protein family that this protein belongs to?
Belongs to the ZAR1 family.
Protein: SYD_SHIDS
Sequence: MRTEYCGQLRLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGIVQVFFDPDRADALKLASELRNEFCIQVTGTVRARDEKNINRDMATGEIEVLASSLTIINRADVLPLDSNHVNTEEARLKYRYLDLRRPEMAQRLKTRAKITSLVRRFMDDHGFLDIETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDVETSFMTAPQVREVMEALVRHLWLEVKGVDLGDFPVMTFAEAERRYGSDKPDLRNPMELTDVADLLKSVEFAVFAGPANDLKGRVAALRVPGGASLTRKQIDEYGNFVKIYGAKGLAYIKVNERAKGLEGINSPVAKFLNAEIIEAILDRTAAQDGDMIFFGADNKKIVADAMGALRLKVGKDLGLTDESKWAPLWVIDFPMFEDDGEGGLTAMHHPFTSPKDMTAAELKAAPENAVANAYDMVINGYEVGGGSVRIHNGDMQQTVFGILGINEEEQREKFGFLLDALKYGTPPHAGLAFGLDRLTMLLTGTDNIRDVIAFPKTTAAACLMTEAPSFANPTALAELSIQVVKKAENN
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROB_STRT1
Sequence: MKRNFDSVKRLVIKIGTSSLVLPSGKINLEKIDQLAFVISSLHNKGIEVVLVSSGAMGFGLNVLDLETRPAEVGKQQAVSSVGQVAMMSLYSQVFSHYQTKVSQLLLTRDVVEYPESLANAINAFESLFELGVVPIVNENDAVSVDEMDHATKFGDNDRLSAIVAKVVGADLLIMLSDIDGLFDKNPNVYEDATLRSYVPEITEEILASAGAAGSKFGTGGMMSKIKSAQMVFENQSQMVLMNGENPRDILRVLEGAKIGTLFKQED
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS4_ROSS1
Sequence: MEIIPAIDMQGGRCVRLYQGDFQRVTVYDDDPVAVAHRWVAQGAPRLHLVDLDGARSGHPVHTDIIRAIVQSVDAPVQLGGGLRSIAAVERALELGVQRVILGTAAVHDPELIRQLVQQFGDAIAIAVDARNDMAATAGWTETAAISAIDLVERMAALGVRRVIYTDIARDGTLSEPNIATTRALVRPGGPAIIASGGISTIDHLRRLAEVGVEGAIVGRALYTGDLSLSDALAAVQ
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FWDG_METJA
Sequence: MKAYELVVYPERCHGCGNCVVSCPVNAKHPETWGGKGPYSDDVVIRVENGVVTVVNQDLCGGCGACIEACPVNAIELVFKRK
What are the official names of this protein?
Polyferredoxin protein FwdG.
Protein: ATG23_ASHGO
Sequence: MNHERILEKRETILQYCHRLTEMHRAALFDEEESPRNLSLQQLRKNIHICLKDLCRLNTWLTEQDGGFRKALGSLERYESKLAALLAKERQLGEERQAWEAAVPAGAGDDSGGVFTVHGGHQRHLNAYIESMGVDNTGLGKEPDALPRLSRQQALGHVAVLRLAQAAVSREISQAEGLLKSFRKDQTFIKAELAKLEAFVRAQKLAVERELEGVRRSQEHIFRKIGLLKLPAREREPLGLGRRPAADLESMKAQMEEFLHVRKSALKAMLSEHKQETQLLKSQQEVWKEVTTLVEDLEDRIRTRFATAAKVDPVELRRLITDAITQIKSLHYEESYPDVLTCIRDEIAALEKANDQLPFSKQKSITDKLVPVNTGAGFLVNSTSPPKVGLTKSIVPSSSMATNKKSV
What is the function of this protein?
Required for cytoplasm to vacuole transport (Cvt) vesicle formation and efficient autophagy.  Plays a role in ATG protein retrieval from the pre-autophagosomal structure (PAS) and is especially required for autophagy-dependent cycling of ATG9.  Also plays a role in regulation of filamentous growth (By similarity).
What are the official names of this protein?
Autophagy-related protein 23.
What is the protein family that this protein belongs to?
Belongs to the ATG23 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: RS4_METPP
Sequence: MARYLGPKAKLARREGTDLFLKSARRAIGDKSKFETKPGQHGRTSGSRTSDFGLQLREKQKVKRMYGVLERQFRRYFAEAERRKGNTGANLLLLLESRLDNVVYRMGFGSTRAEARQLVSHKGITVNGEVVNIASYLVKTGDVVAVREKAKKQLRVTESLKLAESMGLPAWVQVDATKLEGVFKKSPDRDEFGSDINESLIVELYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RHPN1_HUMAN
Sequence: MILEERPDGAGAGEESPRLQGCDSLTQIQCGQLQSRRAQIHQQIDKELQMRTGAENLYRATSNNRVRETVALELSYVNSNLQLLKEELEELSGGVDPGRHGSEAVTVPMIPLGLKETKELDWSTPLKELISVHFGEDGASYEAEIRELEALRQAMRTPSRNESGLELLTAYYNQLCFLDARFLTPARSLGLFFHWYDSLTGVPAQQRALAFEKGSVLFNIGALHTQIGARQDRSCTEGARRAMEAFQRAAGAFSLLRENFSHAPSPDMSAASLCALEQLMMAQAQECVFEGLSPPASMAPQDCLAQLRLAQEAAQVAAEYRLVHRTMAQPPVHDYVPVSWTALVHVKAEYFRSLAHYHVAMALCDGSPATEGELPTHEQVFLQPPTSSKPRGPVLPQELEERRQLGKAHLKRAILGQEEALRLHALCRVLREVDLLRAVISQTLQRSLAKYAELDREDDFCEAAEAPDIQPKTHQKPEARMPRLSQGKGPDIFHRLGPLSVFSAKNRWRLVGPVHLTRGEGGFGLTLRGDSPVLIAAVIPGSQAAAAGLKEGDYIVSVNGQPCRWWRHAEVVTELKAAGEAGASLQVVSLLPSSRLPSLGDRRPVLLGPRGLLRSQREHGCKTPASTWASPRPLLNWSRKAQQGKTGGCPQPCAPVKPAPPSSLKHPGWP
What is the function of this protein?
Has no enzymatic activity.  May serve as a target for Rho, and interact with some cytoskeletal component upon Rho binding or relay a Rho signal to other molecules.
What are the official names of this protein?
Rhophilin-1, GTP-Rho-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the RHPN family.
Protein: SEP12_BOVIN
Sequence: MDPLRQSPSPSSSRASSPRTLSCERLGYVGIEAVLDQLKIKAMKMGFEFNIMVVGQSGLGKSTMVNTLFKSKIWKSTMPGLRVPMPQTLQLHYVTHVIEENGVKLKLTVTDTPGFGDQINNDKCWDPILGYINEQYERYLQEEILITRQRHIPDTRVHCCIYFVPPTGHCLRPLDLEFLQRLCRAVNVVPVIARADSLTIEEREAFRHRIQDDLKTHSIEVYPQKSFDEDVNDKILNSKIRERIPFAVVGADREHMVNGRCVLGRKTKWGIIEVENMAHCEFPLLRDLLIRSHLQDLKDITHNVHYENYRIIRLKESHALPQGPGWVNLAPAPPPAPTGTRASPGPAKMCRWAEDNSDEDF
What is the function of this protein?
Filament-forming cytoskeletal GTPase (By similarity).  May play a role in cytokinesis (Potential).  Involved in spermatogenesis.  Involved in the morphogenesis of sperm heads and the elongation of sperm tails probably implicating the association with alpha- and beta-tubulins.  Forms a filamentous structure with SEPTIN7, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (By similarity).
What are the official names of this protein?
Septin-12.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Cell projection, cilium, flagellum. Note=At interphase, forms a filamentous structure in the cytoplasm. During anaphase, translocates to the central spindle region and to the midbody during cytokinesis (By similarity). Found in the sperm annulus (By similarity).
Protein: GLRA2_MOUSE
Sequence: MYRQLVNILTALFAFFLGTNHFREAFCKDHDSRSGKHPSQTLSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQMKDGTAVKATPANPLPQPPKDADAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK
What is the function of this protein?
Glycine receptors are ligand-gated chloride channels.  Channel opening is triggered by extracellular glycine.  Channel opening is also triggered by taurine and beta-alanine.  Plays a role in synaptic plasticity (PubMed:26370147).  Contributes to the generation of inhibitory postsynaptic currents, and is involved in the down-regulation of neuronal excitability.  Plays a role in cellular responses to ethanol.
What are the official names of this protein?
Glycine receptor subunit alpha-2.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA2 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Synapse. Cell membrane; Multi-pass membrane protein. Cell projection.
Protein: YR842_MIMIV
Sequence: MNSQNYSINNFKQIFDNDILSDVKLILKDNNKELSLNLHKIVLFTHCKFFQAMFVGFEESTKKEVVLNVQNVDICRDIIKEFYGFKSPSVTRYQNWKCRLEYHICCNYFLIDNKFPDIVNINKSCFDDLLNLIDKINYNDVTIRLLAKNLPSNYDLSKLPLELVKKMRNKSCYSGFVFFGNEKHLCIADENFDNIRKFQYGIDLGNDYCYMPNSNKIVRVVSNYVANFSLQSESFECYKIRTKKFNKKFDKKYKIKSSDSFEKPIYNSLRNEIIIIHRKKKYSIICVLDAKKFDLVRTICKFKKSKEKLCHMALSYDCNKLVFVLTIINEVNNKNTEIYVKYLDTGVQERIYKTNRIVNDLKFLNNDIIVFYNNKNNSGHLKTYDISKHKKLPGLTTFPITHISICQEKYVIIVTNMYTHIMVSKKFSGIKYFENCKVVCSPSGKIVSYGNSKNFLTSIDDYENYKTLDSLEINSILPVNVKYDIHDKLNDYIDSLKKIEEENI
What are the official names of this protein?
Putative BTB/POZ domain-containing protein R842.
What is the protein family that this protein belongs to?
Belongs to the mimivirus BTB/WD family.