PharMolix/UniProtQA huggingface dataset:
Protein: HEPA_HHV2H
Sequence: MEAPGIVWVEESVSAITLYAVWLPPRTRDCLHALLYLVCRDAAGEARARFAEVSVGSSDLQDFYGSPDVSAPGAVAAARAATAPAASPLEPLGDPTLWRALYACVLAALERQTGRWALFVPLRLGWDPQTGLVVRVERASWGPPAAPRAALLDVEAKVDVDPLALSARVAEHPGARLAWARLAAIRDSPQCASSASLAVTITTRTARFAREYTTLAFPPTRKEGAFADLVEVCEVGLRPRGHPQRVTARVLLPRGYDYFVSAGDGFSAPALVALFRQWHTTVHAAPGALAPVFAFLGPGFEVRGGPVQYFAVLGFPGWPTFTVPAAAAAESARDLVRGAAATHAACLGAWPAVGARVVLPPRAWPAVASEAAGRLLPAFREAVARWHPTATTIQLLDPPAAVGPVWTARFCFSGLQAQLLAALAGLGEAGLPEARGRAGLERLDALVAAAPSEPWARAVLERLVPDACDACPALRQLLGGVMAAVCLQIEQTASSVKFAVCGGTGAAFWGLFNVDPGDADAAHGAIQDARRALEASVRAVLSANGIRPRLAPSLAPEGVYTHVVTWSQTGAWFWNSRDDTDFLQGFPLRGAAYAAAAEVMRDALRRILRRPAAGPPEEAVCAARGVMEDACDRFVLDAFGRRLDAEYWSVLTPPGEADDPLPQTAFRGGALLDAEQYWRRVVRVCPGGGESVGVPVDLYPRPLVLPPVDCAHHLREILREIQLVFTGVLEGVWGEGGSFVYPFDEKIRFLFP
What is the function of this protein?
Component of the helicase/primase complex.  Unwinds the DNA at the replication forks and generates single-stranded DNA for both leading and lagging strand synthesis.  The primase synthesizes short RNA primers on the lagging strand that the polymerase presumably elongates using dNTPs.  The primase-associated factor has no known catalytic activity in the complex and may serve to facilitate the formation of the replisome by directly interacting with the origin-binding protein and the polymerase.
What are the official names of this protein?
DNA helicase/primase complex-associated protein, HEPA, Primase-associated factor.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae HEPA family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: RL35_ACIF5
Sequence: MPKMKSNRGAAKRFKRTGSGKFKHRQAFLNHILTKKTTKRKRHLRHTLVTSGSDQAALRRMLPYG
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: RL19_CHLT3
Sequence: MNEKIKLVEAAQMRADIPEIHPGDTLKVHVKVVEGDKERLQLFQGILISIRGVGMSKTITVRKISHGVGVERIIPLHSPIIEKIEVVKRGKVRRAKLFYMRNRTGKAAMKIKEKTTNSEMA
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: RL28_BORBZ
Sequence: MARKCEITGKKTMFGNNVPRKGLAKKKGGAGQHIGVKTKRTFKVNLINKKFFIPNLGRSVSIKVSANALRSISKIGLDAFLKKNCKKIENFL
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: AMYG_CLOS0
Sequence: MSRKLIKYLPLLVLASSVLSGCSNNVSSIKIDRFNNISAVNGPGEEDTWASAQKQGVGTANNYVSKVWFTLANGAISEVYYPTIDTADVKEIKFIVTDGKSFVSDETKDTISKVEKFTDKSLGYKLVNTDKKGRYRITKEIFTDVKRNSLIMKAKFEALEGSIHDYKLYLAYDPHIKNQGSYNEGYVIKANNNEMLMAKRDNVYTALSSNIGWKGYSIGYYKVNDIMTDLDENKQMTKHYDSARGNIIEGAEIDLKKNSQFEIVLSFGNSEDEAVKASIETLSENYDSLKSAYIDEWEKYCNSLNNFNGKANSLYYNSMMILKASEDKTNKGAYIASLSIPWGDGQGDDNTGGYHLVWSRDLYHVANAFIAAGDVDSANRSLDYLAKVVKDNGMIPQNTWISGKPYWTGIQLDEQADPIILSYRLRRYDLYDSLVKPLADFIIKMGPKTGQERWEEIGGYSPATMAAEVAGLTCAAYIAEQNKDYESAQKYQEKADNWQKLIDNLTYTEHGPLENGQYYIRIAGLPDPNADFTISIANGGGVYDQKEIVDPSFLELVRLGVKSPDDPKILNTLRVVDSTIKVDTPKGPSWYRYNHDGYGEPSKTELYHGAGKGRLWPLLTGERGMYEIAAGKDATPYLKAMENFANEGGIISEQVWEDTGLPTDSASPLNWAHAEYVVLFPSNIEHKVLDMPDIVYKRYVAK
What is the function of this protein?
CGA has typical kinetic properties for a glucoamylase, but this bacterial enzyme had higher isomaltose-hydrolyzing activity than other eukaryotic glucoamylases.
What are the official names of this protein?
Glucoamylase, 1,4-alpha-D-glucan glucohydrolase, Glucan 1,4-alpha-glucosidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 15 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: NADE_LISMC
Sequence: MEIRERILADMQVAETIDAHEEIRKSVEFLKAYLKKNTFLKSFVLGISGGQDSTLTGKLAQMAISEMRAETGDDEYQFFAVSLPYGTQLDESDRQDALNFMEPDNRLTVNIKASVDASVAALAEAGVELSDFAKGNEKARERMKVQYAIAAMHKGVVVGTDHSAEAVTGFYTKYGDGGTDINPLFRLNKRQGKALLKELGCPEHLYLKKPTADLEDNKPALPDEVALGVTYDQIDDYLEGKEVPADAAAKIENWFIKTEHKRHMAITIFDDFWK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: SEC31_AJECA
Sequence: MVRLREIPRTAALAWSPGSASPYIATGTRAGAVDADFSNETDLELWDLALEQEGGSAELQPAAKLSTESGFHDLAWTESEDSSRGIIAGALENGSLDLWNADKLLSGASDPLVSRASQHSGPVKTLQFNPRHSNLLATGGSKGELFISDLNNIDHPFRLGNVNARLDDIECLDWNKKVPHILVTGSSAGFVTVWDVKTKKESLTLNNLGRKAVSAVAWDPEKPTKLITSIPLETDPLILVWDLRNSNAPERVLRGHESGVLSLSWCAQDPDLLLSSGKDNRTICWNPQTGVQYGEFPVVTNWTFLTRWNPHNPNMFATASFDGRISIQTIQNTKSDAIAQAGASQVQPVDDEDFFAKAQSQPQASTFSLPTAPKWLQRPSSVSFGFGGRVISVGLTDPSKPASRTSKVRITRFEVDSILSSTTQTFEEALKAGDLRRICETRIENAQNDSDRVDWKIIETLISDNPKMQLINYLGFSSEVDETADSLSKLGLGKSEDGGANGVPESDSRGPGVKKHKRLSSIFDTHADSDNFLTDLSASKGAKTNNPFQIYTGSESEADRGITRALLLGDFEKALDICLQEDRMSDAFMVAICGGQKCIDKAQEAYFQKQLEGPNYLRLMAAIVGKNLWDIVHNAGLANWKEAIATICTFATDAEFPDLCETLGDRLEEQAKAEGDKESRKNAAFCFLASSKLEKVVGIWIDELQENENKAIQEATNGETSFSIHVRALQNLIEKVTVFRHVTKFEDAETQKPSDWKLTLLYDKYIEYADVAAAHGQLGVAERYLDLLPQAHPAAVVARNRIKLATEKTTARSAPAHISAASHLTTKPPQQPNVPRGMYNPSAPMTQANNLFKPPAPMQVSNPYAPTGASSAYSPAGYQPSQQHQPTVPLGGPPQAFGTAQQSNIAPPPRAANQSPSTVTSYTQATNLPAWNDLPEGFAKALTPRRGTPSAAAATISSPFPHQQPPQPSQSPQTISPHQPPPPRQRTSMAVPPPPRGPAPPRMTSPPAVGQPHGFPSTRKTSLNFKCIYPTTQHTPTGPGMNVPQIPRGPSPYNAPPTGPPPSNRYAPSPAAQPSAPQPPRAAVAAPPPTGPPAPAPAQSPYSYQHPPPAHGSYAPPSAPTGARPDHQPQHQPPPPGSSPVSRPGTAQSQRKPAPAAKYPPGDRSHIPANAQPIFEILSADMQRVKARAPTSFKAQVNDAERRLNILFDHLNNEDLLKPATVESMAELARALQARDYETAQSIHLDIFTNRNDECGNWMVGVKRLIGMSRATP
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
What are the official names of this protein?
Protein transport protein SEC31.
What is the protein family that this protein belongs to?
Belongs to the WD repeat SEC31 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CADH4_RAT
Sequence: NVPENSRGPFPQQLVRIRSDKDNDIPIRYSITGVGADQPPMEVFNIDSMSGRMYVTRPMDREERASYHLRAHAVDMNGNKVENPIDLYIYVIDMNDNRPEFINQVYNGSVDEGSKPGTYVMTVTANDADDSTTANGMVRYRIVTQTPQSPSQNMFTINSETGDIVTVAAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTTSTFAGEVPENRIETVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVDYELNRAFMLTI
What is the function of this protein?
Cadherins are calcium-dependent cell adhesion proteins.  They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.  May play an important role in retinal development.
What are the official names of this protein?
Cadherin-4, Retinal cadherin, R-CAD, R-cadherin.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: LONP2_ARATH
Sequence: MAETVELPSRLAILPFRNKVLLPGAIIRIRCTSHSSVTLVEQELWQKEEKGLIGILPVRDDAEGSSIGTMINPGAGSDSGERSLKFLVGTTDAQKSDAKDQQDLQWHTRGVAARALHLSRGVEKPSGRVTYVVVLEGLSRFNVQELGKRGPYSVARITSLEMTKAELEQVKQDPDFVALSRQFKTTAMELVSVLEQKQKTGGRTKVLLETVPIHKLADIFVASFEMSFEEQLSMLDSVDLKVRLSKATELVDRHLQSIRVAEKITQKVEGQLSKSQKEYLLRQQMRAIKEELGDNDDDEDDVAALERKMQAAGMPSNIWKHAQRELRRLKKMQPQQPGYNSSRVYLELLADLPWDKASEEHELDLKAAKERLDSDHYGLAKVKQRIIEYLAVRKLKPDARGPVLCFVGPPGVGKTSLASSIAAALGRKFVRLSLGGVKDEADIRGHRRTYIGSMPGRLIDGLKRVGVCNPVMLLDEIDKTGSDVRGDPASALLEVLDPEQNKSFNDHYLNVPYDLSKVVFVATANRVQPIPPPLLDRMELIELPGYTQEEKLKIAMRHLIPRVLDQHGLSSEFLKIPEAMVKNIIQRYTREAGVRSLERNLAALARAAAVMVAEHEQSLPLSKDVQKLTSPLLNGRMAEGGEVEMEVIPMGVNDHEIGGTFQSPSALVVDETMLEKILGPPRFDDSEAADRVASAGVSVGLVWTTFGGEVQFVEATSMVGKGEMHLTGQLGDVIKESAQLALTWVRARASDFKLALAGDMNVLDGRDIHIHFPAGAVPKDGPSAGVTLVTALVSLFSQKRVRADTAMTGEMTLRGLVLPVGGIKDKILAAHRYGIKRVILPQRNSKDLVEVPAAVLSSLEVILAKRMEDVLENAFEGGCPWRNNYSKL
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix (By similarity).  Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import.
What are the official names of this protein?
Lon protease homolog 2, peroxisomal.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Peroxisome matrix.
Protein: TIG_SHESM
Sequence: MQVSVEATQGLERRLTISVPAEQIEKLVKDSLQREAKRARIPGFRPGKVPVTVINKRYGAAIRQDITGEVMQRNFIEAIIAEKLNPAGAPTFVPGATDGEKFEFVATFEIYPEVELKGLDAIEVEQPKASVTDADVDSMIETLRKQHATFAAVEREAADGDKVKMNFVGSVDGVEFEGGKADDFELQLGSGRMIPGFEAGILGHKAGEEFVIDVTFPEEYHAENLKGKAAKFAITLTEVLAANLPEVNDEFAALFGISEGGLEALKTEIRKNMNRELEQALKANVKEQVINGLLANNDIELPKALIDGEVNVLRQQAMQRFGGQTANMPELPAELFTEQAARRVKIGLLLGEVIKTNELKAEDERVQALIASMASAYEDPSEVVAYYNSNKELMQNMRNVALEEQAVEALLKSAKVTEKEVAFEEFMNKATGRA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: ALDA_STAA8
Sequence: MAVNVRDYIAENYGLFINGEFVKGSSDETIEVTNPATGETLSHITRAKDKDVDHAVKVAQEAFESWSLTSKSERAQMLRDIGDKLMAQKDKIAMIETLNNGKPIRETTAIDIPFAARHFHYFASVIETEEGTVNDIDKDTMSIVRHEPIGVVGAVVAWNFPMLLAAWKIAPAIAAGNTIVIQPSSSTPLSLLEVAKIFQEVLPKGVVNILTGKGSESGNAIFNHDGVDKLSFTGSTDVGYQVAEAAAKHLVPATLELGGKSANIILDDANLDLAVEGIQLGILFNQGEVCSAGSRLLVHEKIYDQLVPRLQEAFSNIKVGNPQDEATQMGSQTGKDQLDKIQSYIDAAKESDAQILAGGHRLTENGLDKGFFFEPTLIAVPDNHHKLAQEEIFGPVLTVIKVKDDQEAIDIANDSEYGLAGGVFSQNITRALNIAKAVRTGRIWINTYNQVPEGAPFGGYKKSGIGRETYKGALSNYQQVKNIYIDTSNALKGLY
What are the official names of this protein?
Putative aldehyde dehydrogenase AldA.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: SRBPH_CAEEL
Sequence: MNEEFEGDVPMSDPFLSLVTKLDDIAPFPNNDPLDFDMEHNWQEPGPSQQPDPSIPGNQHSPPQEYYDIDGQRDVSTLHSLLNHNNDDFFSMRFSPPNFDLGGGRGPSLAATQQLSGEGPASMLNPLQTSPPSGGYPPADAYRPLSLAQQLAAPAMTPHQAASLFVNTNGIDQKNFTHAMLSPPHHTSMTPQPYTEAMEHINGYMSPYDQAQGPSGPSYYSQHHQSPPPHHHHHHPMPKIHENPEQVASPSIEDAPETKPTHLVEPQSPKSPQNMKEELLRLLVNMSPSEVERLKNKKSGACSATNGPSRSKEKAAKIVIQETAEGDEDEDDEDSDSGETMSQGTTIIVRRPKTERRTAHNLIEKKYRCSINDRIQQLKVLLCGDEAKLSKSATLRRAIEHIEEVEHENQVLKHHVEQMRKTLQNNRLPYPEPIQYTEYSARSPVESSPSPPRNERKRSRMSTTTPMKNGTRDGSSKVTLFAMLLAVLIFNPIGLLAGSAIFSKAAAEAPIASPFEHGRVIDDPDGTSTRTLFWEGSIINMSYVWVFNILMIIYVVVKLLIHGDPVQDFMSVSWQTFVTTREKARAELNSGNLKDAQRKFCECLATLDRSLPSPGVDSVFSVGWECVRHLLNWLWIGRYIARRRRSTTKPVSVVCRSHAQTAVLYHEIHQLHLMGITGNFEDTYEPSALTGLFMSLCAVNLAEAAGASNDGLPRAVMAQIYISASIQCRLALPNLLAPFFSGYFLRRARRHVRRAPEHSVSHLLWIFHPATRKFMSDAKRLEHVLSSKQKQLRFGSFVEDEQLSPLARIRTTLKVYLLSKLVQELVGGDEIFTKNVERILNDNDRLDDEVDVVDVSRLLVTISTQCAAILTNEKDESAKFGTWISRNGDACCTWWTHVLTCGIYWRSNKNELARQHYSLIRNCPPKILTDNLGLAVGHALCARKICIDDRDSPKVSQYVCIHTKKSLESLRLFSTSSRASGVVSGIQEGTRRMAYEWIMNSLLDAWRSNLFASKPYWTQSFKGQSTFSTLYQEAYNHYAIINGTRGDCWRLFVYELTCRMLNGANPQATWSGVRRVRSTKMDAVRGRVSMRRSAQPDAFHLHTLVKLHTSMDL
What is the function of this protein?
Key transcription factor that regulates expression of genes involved in sterol biosynthesis and lipid homeostasis.
What are the official names of this protein?
Sterol regulatory element binding protein sbp-1, SREBP sbp-1.
Protein: PG153_VACCW
Sequence: MANIINLWNGIVPTVQDVNVASITAFKSMIDETWDKKIEANTCISRKHRNIIHEVIRDFMKAYPKMDENKKSPLGAPMQWLTQYYILKNEYHKTMLAYDNGSLNTKFKTLNIYMITNVGQYILYIVFCIISGKNHDGTPYIYDSEITSNDKNFINERIKYACKQILHGQLTIALRIRNKFMFIGSPMYLWFNVNGSQVYHDIYDRNAGFHNKEIGRLLYAFMYYLSISGRFLNDFALLKFTYLGESWTFSLSVPEYILYGLGYSVFDTIEKFSNDAILVYIRTNNRNGYDYVEFNKKGIAKVTEDKPDNDKRIHAIRLINDSTDVQHIHFGFRNMVIIDNECANIQSSAENATDTGHHQDSKINIEVEDDVIDDDDYNPKPTPIPEPHPRPPFPRHEYHKRPKLLPVEEPDPVKKDADRIRLDNHILNTLDHNLNFIGHYCCDTAAVDRLEHHIETLGQYAVILARKINMQTLLFPWPLPTVHPHAIDGSIPPHGRSTIL
What is the function of this protein?
Envelop protein that mediates acid-dependent endocytosis into host cells (PubMed:20538855).  Plays an important role in endocytic entry of the virus by acting as an acid-sensitive membrane fusion suppressor (PubMed:22278246, PubMed:31220181).  Low pH in host endosomes triggers conformational changes to allow de-repression of viral fusion complex activity and membrane fusion within vesicles (PubMed:31220181).  Plays also a role in bridging the mature virion with structural protein OPG152.
What are the official names of this protein?
Envelop protein OPG153.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG153 protein family.
Protein: SLM9_SCHPO
Sequence: MHIFVPKLLENHQFSSISSSKDFVAVSAETNVYILSKDFFYPKSSEKRIIQSLNGHKTTHLSFDSPISCIRFTYDGSCLAVATEAGTFLYHSEKWDKAFQVLSGPAYEVCWSQQGHILATSWKQISIYVKDEGLRTETIVKKTEHADSNHQPAVSIEESKEAVESTSQSSEISFKLIKVIEGHHTFVGGLAFDPMGQFLASQSFDHTLKVWKLSTFGVEKSIAKPFEQMPTGNRFLRLSWSPDGAHIASVNAVNEGAYVIAIVQRDTWTYDINLVGHQGPLECATFNPYLYEDPFQKSIIASAAHDGCVSIWNTACARPMAVIHELSCSSFVDLQWSTSGFELYGVSLDGNLMLLQFEESEFGEKMDTIHYPDDLSYFNSSRSKAHVNKNAAADRTTSPTQGQPESPSKSILLRPPPSIASSPESKRRKCPKKFVARPPVPHPTSLYSQIRIGCPYLKPKLVISKSFGTLIVKNHNQLSLLKCTFSNLDGNDCSWFSYLPNAIVLANGTSVFWAVATEDSSIYIYSPAGRLLLPPVVVAATPCFLECCGDFLCCIVSTGLLYIWNIKNFEAIHSPVSTLPLFHSNFSVSKIARGPSIEQFFVTKQGHPVAIMSDGNAFAFIRDSSSWLRVSEGWWMIGSQYWGPLASESNEESPLGFLERCTDEEIIKAGRGRFLQRLVKALMLRQGYDNYEMLVSIRHLENRLMSSAKLDLEYDFRENLILYAKKIAEEGMKDKMDELCKELLGPLRIPHNGIDTVKVGNRLWSPTIAGNNKRNLLKDIIIHTAKYRDMQRITSQYSDLLRRSALL
What is the function of this protein?
Probably required for replication-independent chromatin assembly (By similarity).  Required for transcriptional silencing in the outer repeat (otr) centromeric repeats and the Tf2 long terminal repeat retrotransposons.  May play an indirect role in the regulation of cdc2 and/or wee1 at the G2/M stage of mitosis.
What are the official names of this protein?
Histone transcription regulator slm9.
What is the protein family that this protein belongs to?
Belongs to the WD repeat HIR1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL38_ANOGA
Sequence: MPQEIKEVKDFLIKARRKDARAVKIKKNETNTKFKIRCSRYLYTLVVKDMEKAEKLKQSLPPGLQVKEVK
What are the official names of this protein?
60S ribosomal protein L38.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL38 family.
Protein: HPS2_STAS1
Sequence: MELQLAIDLLNKEDAAELANKVKDHVDIVEIGTPIVINEGLPAVQHLNDNVDGVKVLADLKIMDAADYEVSQAVKFGADIVTILGVAEDASIKAAVDEAHKHGKQLLVDMIAVQDLEKRAKDLDDLGADYIAVHTGYDLQAEGQSPLESLRKVKSVISNSKVAVAGGIKPDTIKDIVAENPDLIIVGGGIANADDPVEAAKQCRDIVDAHTKA
What is the function of this protein?
Catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate.
What are the official names of this protein?
3-hexulose-6-phosphate synthase 2, HPS 2, D-arabino-3-hexulose-6-phosphate formaldehyde lyase 2.
What is the protein family that this protein belongs to?
Belongs to the HPS/KGPDC family. HPS subfamily.
Protein: RLMN_STRPI
Sequence: MKPSIHSLTHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEEMTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLSVCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERVSHIVVMGIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSTLGLAHKIRDFADEGVQVNLAVSLHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALELAELLKNIKKLSYVNLISYNPVSEHDQYSRSPKERVLAFYDTLKKKGGNCVVRQEHGTDIDAACGQLRSNTMKRDRQKAVAAVNP
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGA_HELPH
Sequence: MQDFSSLLLKLQEYWKNQGCLVIQPYDIPAGAGTFHPATLLRSLDKKPWNVAYVAPSRRPTDGRYGENPNRLGSYYQFQVVIKPSPSNIQEMYLKSLEVLGINLNEHDIRFVEDNWESPTLGAWGLGWEVWLDGMEVTQFTYFQQVGGIPCSPIPVEITYGLERLAMYVQKVENILEIEWAKNNHDSVRYAQVHLESEYQFSKYHFEIASVRRLLEMFKNAQAEALHCLENKLPLPAYDFVMLCSHFFNILDARKAISVAERQNYILQIRDLAKGCAVLYKEQEKEREERLKNALTKA
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABI_NOSS1
Sequence: MLNLTGKNALVTGIANNRSIAWGIAQQLHAAGANLGITYLPDERGKFEKKVSELVEPLNPSLFLPCNVQNDEQIQSTFDTIRDKWGRLDILIHCLAFANRDDLTGDFSQTSRAGFATALDISTFSLVQLSGAAKPLMTEGGSIITLSYLGGVRAVPNYNVMGVAKAGLEASVRYLASELGSQNIRVNAISAGPIRTLASSAVGGILDMIHHVEQVAPLRRTVTQLEVGNTAAFLASDLASGITGQVLYVDAGYEIMGM
What is the function of this protein?
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).  Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity).
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI, ENR, NADH-dependent enoyl-ACP reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Protein: COAE_AGRFC
Sequence: MMIVIGLTGSIGMGKTTTAKLFAEEGVPVLDSDEVVHGLYRAEAVPLIDAAFPGTTISGMVDRQKLGDVLRKNPANFNRLEEIVHPLVRNRQEAFLAKARIDDRAFALLDIPLLFETGAEGRVDKVVVVSCAPEIQRERVLSRPGMTEEKFEMILARQMPDAEKRQRADFVVDSGNGVEAARDQVKEILQKLGA
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_STAAB
Sequence: MPRVKGGTVTRARRKKTIKLAKGYFGSKHTLYKVAKQQVMKSGQYAFRDRRQRKRDFRKLWITRINAAARQHEMSYSRLMNGLKKAGIDINRKMLSEIAISDEKAFAQLVTKAKDALK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: DNAJ_TERTT
Sequence: MAKRDYYEVLGVARDVSEQDLKKAYRKVAMKFHPDRNPDDASAEEKFKEASEAYEVLSDKQKRAAYDQFGHAGVEGQGGMGGGAEGFGSFSDIFGDVFGDIFGGAGGGRGRGGPSRGADLRYTLDLSLEDAVRGTSVKIKVPTLVSCTNCGGSGAKPGTTATTCNTCGGHGQVRMQQGFFSVQQTCPTCRGQGKTISDPCNKCHGHGRVEETKTLSVKVPAGVDTGDRIRLAGEGEAGADGGPSGDLYVQVHVKDHEFFQREGRNLYCEVPISIFDACLGGDLEVPTLDGRVKLKVPAETQTGKLFRLRGKGVTPIRGGAAGDLLCRVIVETPVNLSNKQKELLEQLKDTFKGTQHSPKQQSWFEGMKNFFGDMKM
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VILYA_DROME
Sequence: MAKSQAGQTVEPEASKLWIHCNSCCALFCDKKHTFFLLACHHVFCERCVKVSAGRTPSDAPIFECSTCRRSVRGRQLTNSMPNHFKQLFHPEPFTIGNDFVETFQRGNHRHFDKYKERKELEMDKLFKDIEVAKSVCQKRFLEAQMLRVERKKLMQRSRYIKAEVANRKAEMHRMAQAYRSRSLTSQSSSSAQRSARGRPRGRGTATQSSSRRRSTESAKRQQITSFIHPPNNSFDL
What is the function of this protein?
Required for the formation of DNA double-strand breaks during meiosis together with narya and nenya.
What are the official names of this protein?
RING finger protein vilya.
What are the subcellular locations of this protein?
Chromosome. Note=During early pachytene, colocalizes with narya to the central region of the synaptonemal complex (SC) in both linear stretches and discrete foci which correspond to recombination nodules. As pachytene progresses, found mainly at recombination nodules. Double-strand break formation is required for recruitment to recombination nodules but not for linear localization to the central region of the SC.
Protein: RL7_SYNE7
Sequence: MSAKTDEILESLKTLTLLEAAELVKQIEEAFGVSAAAPVGGVVVAAAAGAAAEAVEEKTEFDVVLEEVPADKKIAVLKVVRGITGLGLKEAKDLVEAAPKPIKEGVSKDDAEAAKKELEEAGAKVSVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: OBG_LACH4
Sequence: MPTFVDQTKIEVQAGKGGDGMVAFRHEKYVPNGGPAGGDGGRGGSIIFVADSGLRTLMDFRYRRKFKADSGENGRIKSQYGRAAKDLYLKVPVGTTVYDFNTGELIGDLVEKGQELVVAKGGRGGRGNIHFATSVNTAPEIAENGEPGEDRVLRLELKLLADVGLVGFPSVGKSTLLSVTTKAKPKIAAYEFTTLTPNLGMVILPDGRDFSMADLPGLIEGASQGVGLGIQFLRHVERTKVILHLVSMDPNNGREAIEDYHTIKNELKNYETDLSKKRELIVASQMDISGAEEKLAAFKKALKEEGNNEPVYEISSVTHKGVSKLMNDTATLVEEVEKERAEEEPKVVQKTKEYKYKAPQKNEFTVEKVGEHEFVVKGEQLERLVQMTNLDHQDGIMRLARRLKRLGVDDALREKGAVNGDDVAIGKFVFEFVQ
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VSPC_CROAD
Sequence: MVLIRVLANLLILQLSYAQKSSELVIGGDECNINEHRFLVALYDPDRFLCSGILLNEEWVLTAAHCDRRNIRIKLGMHSKTVPNEDEQTRVPKEKFFCLSSKNYTLWDKDIMLIRLDSPVSNSEHIAPLSLPSSPPSVGSVCRIMGWGRISPSKETYPDVPHCANINLLDYEVCLAAYPEFGLPATSKTLCAGILEGGKDTCVGDSGGPLICNGQFQGILSWGNDVCGYILQPALYTRVFDHLDWIQSIIAGNTDVTCPP
What is the function of this protein?
Snake venom serine protease that may act in the hemostasis system of the prey.
What are the official names of this protein?
Snake venom serine proteinase 12, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.