PharMolix/UniProtQA huggingface dataset:
Protein: SPTC1_BOVIN
Sequence: MATVAEQWVLVEMVQALYEAPAYHLILEGILILWIIRLLFSKTYKLQERSDLTLKEKEELIEEWQPEPLVPPVSKDHPALNYNIVSGPPSHNIVVNGKECINFASFNFLGLLDNPRLKAAALASLKKYGVGTCGPRGFYGTFDVHLDLEDRLAKFMKTEEAIIYSYGFATIASAIPAYSKRGDIVFVDKAACFAIQKGLQASRSDIKVFNHNDMDDLERLLKEQEIEDQKNPRKARVTRRFIIVEGLYMNTGTVCPLPELVKLKYKYKARIFLEESLSFGVLGEHGRGVTEHFGISIDDIDLISANMENSLASIGGFCCGRSFVIDHQRLSGQGYCFSASLPPLLAAAAIEALNIMEENPGIFAVLKEKCKRIHKALQGIPGLKVVGESISPALHLQLEETTGCRERDVKLLQEIVTQCMDRGIALTQARYLEKEEKYLPPPSIRVVVTVEQTEEDLEKAASTISEVAQTVLL
What is the function of this protein?
Serine palmitoyltransferase (SPT).  The heterodimer formed with SPTLC2 or SPTLC3 constitutes the catalytic core.  The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference.  The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC3-SPTSSA isozyme uses both C14-CoA and C16-CoA as substrates, with a slight preference for C14-CoA.  The SPTLC1-SPTLC2-SPTSSB complex shows a strong preference for C18-CoA substrate, while the SPTLC1-SPTLC3-SPTSSB isozyme displays an ability to use a broader range of acyl-CoAs, without apparent preference (By similarity).  Required for adipocyte cell viability and metabolic homeostasis (By similarity).
What are the official names of this protein?
Serine palmitoyltransferase 1, Long chain base biosynthesis protein 1, LCB 1, Serine-palmitoyl-CoA transferase 1, SPT 1, SPT1.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: MURI_HAEIN
Sequence: MDKKEKRPTVLFFDSGVGGFSVYREAKKLLPNWHYLYCFDNAGFPYSERKEESIIHRTLAACQLINQRYPLDAMVIACNTASTVVLPPLRAAFDIPIIGTVPAIKPASEITKTKHIGLLATKGTVKRHYIDELIDKFAQDCIVERLGTTKLVEIAEQKIRGHSVDLISLKDELSSWAGMADLDTLVLGCTHFPLIKDEIQLCLPQVKYFMEPSAAIAKRIKYLLDDKNLQAQNEKYNQMFCTAHFPEESQFKKALHLWGFESLEVIKID
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: CATA_BORBR
Sequence: MNAMTNKTLTTAAGAPVADNNNTMTAGPRGPALLQDVWFLEKLAHFDRERIPERVVHAKGSGAYGTFTVTHDISRYTRARIFAEVGKQTPLFLRFSTVAGERGAADAERDVRGFAIKFYTDEGNWDLVGNNTPVFFIRDPLKFPDFIHTQKRDPKTNLRNATAAWDFWSLNPESLHQVTILMSDRGLPQNYRQQHGFGSHTYSFVNDAGERFYVKFHFKSQQGIACYTDGEAAELVGRDRESAQRDLFQNIEQGQFPRWTLKVQVMPEAEAATYHINPFDLTKVWPHADYPLIEVGVLELNKNPENYFAEVEQAAFTPANVVPGIGFSPDKMLQGRLFSYGDTHRYRLGINHHQIPVNAPRCPFHSFHRDGMGRVDGNGGATLNYEPNSFGEWREAKHAAEPPLALDGQAADRWNHRVDEDYYSQPGALFRLMNDDQKQQLFGNIGRHMAGVPEEIQRRQLEHFRRADPAYAAGVAKALGLK
What is the function of this protein?
Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
Protein: SG1C1_RAT
Sequence: MKGSSALLVALTVLCICGLTRAEDDNEFFMEFLQTLLVGTPEELYEGPLGKYNVNDMAKAALTELKSCIDELQPVHKEQLVKLLVQVLDAQEDT
What are the official names of this protein?
Secretoglobin family 1C member 1, Secretoglobin RYD5.
What is the protein family that this protein belongs to?
Belongs to the secretoglobin family.
What are the subcellular locations of this protein?
Secreted.
Protein: LYM_JATCU
Sequence: YSPSLTDLQSYNAMNGPALKAGDILAVPLPA
What are the official names of this protein?
LysM-domain containing protein.
Protein: CYB_DESMS
Sequence: MTNIRKTHPIMKIINDSFIDLPTPSNISSWWNFGSLLGICLVIQIITGLFLAMHYTPDTMTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYMFTETWNIGVLLLFATMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFIIAAMAGVHLLFLHETGSNNPSGLLSDADKIPFHPYYTIKDTLGALALITVLSLLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVMSILVLALMPFLHTSKQRSMMFRPISQCLFWLLVADLLVLTWIGGQPVEHPFIIIGQVASILYFLLILVLMPLASIMENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CD123_NEMVE
Sequence: MKQQHVENCNFSSWYPRFKNVTIRSKIIPLSKEFVDYLKTDGVVLPGKPSSLPRHEDDESDSEEWQNLEEDPEQATVEAPEFNDIDTKIKEAIQELGGEVFPKLNWSAPRDASWISHDNTLRCKSPGDIYLLLKSSDTIDRVLCDAFIHCEDNSTQTHDSFELILRKWQNIYPAMEFRCFVRNNELVAISQRDISNYYHFLAENEDEICADILNFYESKIAEKFPDTSYVFDVYKYADQKCTLIDFSPYGVPTNPLLFTWSELDTEVVPDLLFKVVPSAIGVQPGPFACSRLPQDMVDLTSGADVNKLVDFLNVGNLIRRPGEASDDDS
What is the function of this protein?
Required for S phase entry of the cell cycle.
What are the official names of this protein?
Cell division cycle protein 123 homolog.
What is the protein family that this protein belongs to?
Belongs to the CDC123 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPAP3_XENLA
Sequence: MSSPSKAIELQLQMKQNAEDLQDFMREMESWEKDIKQKDAKLRNQTGVENQILPPIRNKDFKKKKKNKPKPPLEKSQEDCLNPKKKLLDYEYWDKLDVDKALEDIDKDNSNETSSDSECGDEDAITVDTEKALSEKEKGNNYFKSGKYDEAIECYTRGMDADPYNAILPTNRASAFFRLKKFAVAESDCNLAIALNRDYAKAYARRGAARLALKNLQGAKEDYEKVLELDANNFEAKNELRKINQELYSSASDVQENMATEAKITVENEEEKKQIEIQQRKQQAIMQKDLGNAYFKEGKYEIAIECYSQGMEADNTNALLPANRAMAYLKIQKYKEAEADCTLAISLDASYCKAFARRGTASIMLGKQKEAKEDFEMVLKLDPGNKQAVLELAKISQELRSIEKDRNGNKDSNQRKLINTVEKLPHLRSTKPLRRMVIEEVGGPAEIFNTSLKETNHRKADSVDLTAETNTQDLNQEQNICNSPDVPSPKIPKIEEISDTPGSCEPTTGEDYLTSRPSPPKIEKVVSTFSESLNIGIPAVPTNSFQLESDFRRLKGNPDLLYVYLKQIEPTLYGKLFKKALDPDLFSDILTILREQFINKDSPDLIFEILQRLSELKRFDMAVMFLSESDKNNAHILFSHLEQSMNANVSFNALKKKYGL
What is the function of this protein?
May for an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein.
What are the official names of this protein?
RNA polymerase II-associated protein 3.
What is the protein family that this protein belongs to?
Belongs to the RPAP3 family.
Protein: MBL_BACC1
Sequence: MFARDIGIDLGTANVLIHVKGKGIVLNEPSVVAIDRNTGKVLAVGEEARSMVGRTPGNIVAIRPLKDGVIADFEITEAMLKYFINKLDVKSFFSKPRILICCPTNITSVEQKAIREAAERSGGKTVFLEEEPKVAAVGAGMEIFQPSGNMVVDIGGGTTDIAVLSMGDIVTSSSIKMAGDKFDMEILNYIKRKYKLLIGERTSEDIKIKVGTVFPGARSEELEIRGRDMVTGLPRTITVCSEEITEALKENAAVIVQAAKGVLERTPPELSADIIDRGVILTGGGALLHGIDMLLAEELKVPVLIAENPMHCVAVGTGIMLENIDRLPKRALR
What is the function of this protein?
Forms membrane-associated dynamic filaments that are essential for cell shape determination.  Acts by regulating cell wall synthesis and cell elongation, and thus cell shape.  A feedback loop between cell geometry and Mbl localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
What are the official names of this protein?
Cell shape-determining protein Mbl.
What is the protein family that this protein belongs to?
Belongs to the FtsA/MreB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Membrane-associated.
Protein: INHBB_RAT
Sequence: MDGLPGRALGAACLLLLAAGWLGPEAWGSPTPPPSPAAPPPPPPPGAPGGSQDTCTSCGGGGGGFRRPEELGRVDGDFLEAVKRHILSRLQLRGRPNITHAVPKAAMVTALRKLHAGKVREDGRVEIPHLDGHASPGADGQERVSEIISFAETDGLASSRVRLYFFVSNEGNQNLFVVQASLWLYLKLLPYVLEKGSRRKVRVKVYFQEQGHGDRWNVVEKKVDLKRSGWHTFPITEAIQALFERGERRLNLDVQCDSCQELAVVPVFVDPGEESHRPFVVVQARLGDSRHRIRKRGLECDGRTSLCCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNPGPVNSCCIPTKLSSMSMLYFDDEYNIVKRDVPNMIVEECGCA
What is the function of this protein?
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland.  Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition.  Inhibins appear to oppose the functions of activins.
What are the official names of this protein?
Inhibin beta B chain, Activin beta-B chain.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: MNMA_PSESM
Sequence: MRDPAPSNSEMKRVIVGMSGGVDSSVSAVLLMEQGYQVEGLFMKNWEEDDGTEYCTAREDLADAQAVCDRIGIKLHTANFAAEYWDNVFEHFLEEYKAGRTPNPDILCNREIKFKAFLDYALMLGADLIATGHYVRRRDIDGRTELLKGLDPNKDQSYFLHAVGGEQIARTLFPVGELEKPQVRAIAEKHGLATAKKKDSTGICFIGERRFTDFLRQYLPAQPGDIKTTEGEVIGRHSGLMYHTIGQRQGLGIGGLKDASDDPWYVLVKDLDNNELIVGQGNDHPWLFSRALVSSEIYWVNPIDLSSPRKLTAKVRYRQSDQPCTLEKTAGGYRATFDDPQRAVTPGQSVVFYDGEICLGGGVIEIAEPWTSKDKR
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPD_SALDC
Sequence: MAATLLDVCAVVPAAGFGRRMQTECPKQYLSIGNKTILEHSVHALLAHPRVTRVVIAISPGDHRFAQLPLANHPQITVVDGGNERADSVLAGLQAVAKAQWVLVHDAARPCLHQDDLARLLTISENSRVGGILASPVRDTMKRGEPGKNAIAHTVERADLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPALVEGRADNIKVTRPEDLALAEFYLTRTIHQEKA
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: PANB_ACIAD
Sequence: MISLSDLRKFKTEGRKFSCLTCYDASMAKAMEFAEIDSILIGDSLGMVIQGHDSTLPVTVDDMAYHTAAVRRGNQHSFIMTDLPFMSYATLPDALNNAKKVMQAGAQMIKIEGGAWLSESIRVLTQNGIPVCVHLGLTPQSVHVFGGYKLQAKTREAADQLIADCQAVVDAGAAILLLECVPAQLGQEIAELFPQTPVIGIGAGKETDGQVLVAQDMLGLSFGKVARFVRNFMKEQAGETAIVDAFKAYHAAVQDQSFPAREHTFQVEL
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DGAT2_SCHPO
Sequence: MSEETSIPGIIASTPPISKDSRRNVSHWLQALAVFLHSVSLTLTASWYTVLWAFLPFWPFLIVYLIWLIYDDGFVTGKDRQKRWLRNAPPYRWFCHYFPIRLHKTTELDSEKNYIFGYHPHGIISLGAFGGFASEGADFSKLFPGINVSVLTLNSNFYVPVYRDYLMALNINSVSKKSCVSILSRKPGDSVLIVIGGAQESLLSRPGQNNLVLKKRFGFVKLAFLTGSSLVPCFAFGESDIFEQVDNNPRTRIYKFQEIVKKIAGFTVPFFYGRGLLNKTFGLMPWRKPINIVVGEPIDVPKKSHPTNQEIYEVHEEYIRRLEGLWNKYKDVFLPNRISELKLSA
What is the function of this protein?
Catalyzes the terminal and only committed step in triacylglycerol (TAG) synthesis by using diacylglycerol (DAG) and fatty acyl-CoA as substrates.  Required for storage lipid synthesis (PubMed:12963726, PubMed:26990381).  Major DAG esterifying enzyme in stationary phase when TAG production is particularly active (PubMed:12963726).  Involved in lipid particle synthesis from the endoplasmic reticulum, promoting localized TAG production at discrete ER subdomains (PubMed:26990381, PubMed:28011631).
What are the official names of this protein?
Diacylglycerol O-acyltransferase 1, Diglyceride acyltransferase, Triacylglycerol synthase, TAG synthase.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol acyltransferase family.
What are the subcellular locations of this protein?
Lipid droplet. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Localizes to sites of lipid droplet biogenesis in the endoplasmic reticulum.
Protein: RL11_DELAS
Sequence: MAKKIVGFIKLQVPAGKANPSPPIGPALGQRGLNIMEFCKAFNAQTQGVEPGLPLPVVITAFADKSFTFIIKTPPATVLIKKAIKLDKGSSNPLKNKVGKITRAQLEEIANTKLKDMNAADVDAAVRTLAGSARSMGVIVEGV
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: SMAGP_RAT
Sequence: MNNLPATPSPEELMTTPVFQAPETMSPQAEEASTALIAVVITVVFLTLLSVVTLIFFYLYKNKGSYVTYEPAEGEPSAILQMETDSAKGKEKEEYFI
What is the function of this protein?
May play a role in epithelial cell-cell contacts.  May play a role in tumor invasiveness and metastasis formation.
What are the official names of this protein?
Small cell adhesion glycoprotein, Small transmembrane and glycosylated protein.
What is the protein family that this protein belongs to?
Belongs to the SMAGP family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type III membrane protein. Cytoplasmic vesicle membrane; Single-pass type III membrane protein. Note=Predominantly on lateral parts of the membrane, at cell-cell epithelial junctions (PubMed:15021913). Detected on cytoplasmic membranes in undifferentiated tumors.
Protein: PSBC_LEPVR
Sequence: MKTLYSLRRFYHVETLFNGTLALAGRDQETTGFAWWAGNARLINLSGKLLGAHVAHAGLIVFWAGAMNLFEVAHFVPEKPMYEQGLILLPHLATLGWGVGPGGEVIDTFPYFVSGVLHVISSAVLGFGGIYHALLGPETLEESFPFFGYVWKDRNKMTTILGIHLILLGVGAFLLVFKALYFGGVYDTWAPGGGDVRKITNLTLSPSVIFGYLLKSPFGGEGWIVSVDDLEDIIGGHVWLGSICIFGGIWHILTKPFAWARRALVWSGEAYLSYSLAALSVCGFIACCFVWFNNTAYPSEFYGPTGPEASQAQAFTFLVRDQRLGANVGSAQGPTGLGKYLMRSPTGEVIFGGETMRFWDLRAPWLEPLRGPNGLDLSRLKKDIQPWQERRSAEYMTHAPLGSLNSVGGVATEINAVNYVSPRSWLSTSHFVLGFFLFVGHLWHAGRARAAAAGFEKGIDRDFEPVLSMTPLN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP43 reaction center protein, PSII 43 kDa protein, Protein CP-43.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: VPB46_MYCTO
Sequence: MTPTACATVSTMTSVGVRALRQRASELLRRVEAGETIEITDRGRPVALLSPLPQGGPYEQLLASGEIERATLDVVDLPEPLDLDAGVELPSVTLARLREHER
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system.  Neutralizes the effect of cognate toxin VapC46 (By similarity).
What are the official names of this protein?
Antitoxin VapB46.
What is the protein family that this protein belongs to?
Belongs to the phD/YefM antitoxin family.
Protein: ASTE_PSEPK
Sequence: MLALGKLLELTLTDHEPAEKTQVTPKGARLRWLGEGALEVRPAESDDCGLDLLLSAGIHGNETAPIELLERLLHGVANGKIRPRARVLFLFGNPAAIRKGERFIEQDINRLFNGRHELSSGFEALRAAELEQFARVFFSKPGRNRLHYDLHTAIRGSKIEQFALYPYKEGRKHSRRELARLAAAGMEAVLLQSKSSITFSAFTYEQLEAEAFTLELGKARPFGQNEQVNLDKLEERLIRIIEATEPEDESSLDGLQLFSVSREIIKHSDSFHLHLPADIENFSELSKGYLLAEDLAEMRWVVEEEGARIIFPNPKVKNGLRAGILIVPDSGQRLG
What is the function of this protein?
Transforms N(2)-succinylglutamate into succinate and glutamate.
What are the official names of this protein?
Succinylglutamate desuccinylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
Protein: RBL7_ARATH
Sequence: MLSTAAEEDPEGGSRETNNGGETTPDMQWRSWIIPIVVIANVVVFVVVMYYNDCPHKSHRCLAKFLGRFSFESFKSNPLLGPSSSTLEKMGALAWGKIVHKRQVWRLLTCMWLHAGVIHLLANMCCVAYIGVRLEQQFGFVRVGTIYLVSGFCGSILSCLFLEDAISVGASSALFGLLGAMLSELLINWTTYDNKGVAIVMLLVIVGVNLGLGTLPPVDNFAHIGGFFGGFLLGFLLLIHPQFEWEENQVSLMPGTIVKPKYNTCQLVLCIVASIVFVAGFTSGLVILFRGDSLNRYCKWCHKLSYSSKSQWT
What is the function of this protein?
Probable rhomboid-type serine protease that catalyzes intramembrane proteolysis.  May function in embryo development.
What are the official names of this protein?
RHOMBOID-like protein 7, AtRBL7.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PE15_MYCTO
Sequence: MTLRVVPESLAGASAAIEAVTARLAAAHAAAAPFIAAVIPPGSDSVSVCNAVEFSVHGSQHVAMAAQGVEELGRSGVGVAESGASYAARDALAAASYLSGGL
What is the function of this protein?
May play a pivotal role in the evasion of host immune response by M. tuberculosis.  Mediates production of IL-10 via activation of the p38 and ERK1/2 mitogen-activated protein kinase (MAPK) signaling pathways.
What are the official names of this protein?
PE family immunomodulator PE15.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PE family.
What are the subcellular locations of this protein?
Secreted. Cell envelope. Cell surface. Note=Secreted via the ESX-3 / type VII secretion system (T7SS) (By similarity). Secretion is dependent on EsxG and EsxH (By similarity).
Protein: PFKA7_ARATH
Sequence: MSSPRSNKPKIVNGPGGYILQDVPHLIDYLPDLPTYPNPLQDNPAYSVVKQYFVHADDSVPEKVVVHKDGPRGVHFRRAGPRQKVYFESDEVHACIVTCGGLCPGLNTVIREVVSSLSYMYGVKRILGIDGGYRGFYAKNTIPLNSKVVNDIHKRGGTIIGTSRGGHDTNKIVDSIQDRGINQVYIIGGDGTQRGASVIFEEIRRRRLKVAVVGIPKTIDNDIPVIDKSFGFDTAVEEAQRAINAAHVEAESNENGIGFVKLMGRYSGYIAMYATLASRDVDCCLIPESPFYLEGEGGLFEFIERRLKDHGHMVIVLAEGAGQDLMCKSMESTPMDASGNKLLKDVGLWLSQSIKDHFKKNKMVMNLKYIDPTYMIRAVPSNASDNVYCTLLAQSAVHGAMAGYTGYTSGLVNGRQTYIPFYRITETQNNVVITDRMWARLLSSTNQPSFLGPKDTSEEKKELPETPLLDDGAVDIPPVTKEVTK
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase 7, ATP-PFK 7, Phosphofructokinase 7, Phosphohexokinase 7.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPF_BRUC2
Sequence: MATKAAFARMNGLGNQIIVADMRGRADSITSAAAIRLASDSETAFDQIMAIHDPRTPGTDYYIAIINCDGTQAQACGNGTRCVVQALAAETGRHAFTFETRAGILTATEHDDGLISVDMGTPRFDWQDIPLAQAVADTRKIELQVGPADAPVLHSPSIASMGNPHAVFWVDKDVWSYELDKFGPLLENHPIFPERANISIAHVTSSDTIDLRTWERGAGLTRACGSAACAAAVSAARTGRTGRKVTVNVPGGPLLIEWRDDDHVMMTGPAEWEFSGTFDPATGEWSRDTQGLQGSGNADRGTA
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIMT_CUPPJ
Sequence: MSPTPPRSKFPLPLDAVVQRKPAPARTAGMPAVGAPGPAQAQAKARDKQPSAPTAAASAVEARASAATAGGGGMASDRARGALAARLRASGIRDERVLAAIGTVPRHLFVEPGLASQAYEDAALPIGHQQTISKPSVVARMIELLREGLSADTPVERVLEIGTGCGYQAAVLSLVAREVFSIERIRPLHEQAKANLRPLRVPNLRLHYGDGMLGLPQAAPFSAIILAAAGMEVPQALLEQLAIGGRLIAPVAVVPPAGGSGQTVTQQLLLIERLNRHRFHRTALEAVFFVPLKSGTI
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_LIMRJ
Sequence: MIQTIDLKKGMVFERDGKLLKVLQINHHKPGKGNTLMQMDIQDLRSGSIVHTTMRPSEKVEQVNVDKRSAQYLYDEGDSAVFMDLESYEQYSLNHDLLGDDKNYLVENMKVILNFVNGDIIGVELPTTVELTVAETEPMIKGATIDGGGKPATMETGLVVNVPAFIKNGDKLIINTTDGSYKSRA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_ANAMM
Sequence: MVGYIGNVDIGVFDAEVANSMSAELERQNTLLQMIASENFVSRAVLQAQGSVLTNKYAEGYAGSRYYCGCALVDVVENLAVERLCRLFGCKFANVQPHSGSQANQQVFMALLKPGDTILGMSLDCGGHLTHGAAPNVSGRWFNAVSYGVNRDTGLIDMDEVEALALSAKPSLIIAGASSYPRRIDFAAFRAIADKVGAYLLADIAHYSGLIAGGCYPSPFGHAHVVTSTTHKTLRGPRGAVIMTDDEEIHKKIRLSVFPGMQGGPLMHVIAAKAVAFKEALHPDFKLYAQQVLENSRVLAGVLSSEGLDVVTGGTDSHIVLLDLRSKGVTGREVSSSLERAGIVCNKNAVPFDTEKPWVTSGIRLGSAAETSRGLGVPEFESIGRLVAKVVNACSLGQEKMSAAEAEVRREVNGLVRSLPMSAFPVCEVC
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPF_BRUA1
Sequence: MALDIKICGLKTPEAVAAALDGGATHIGFIFFPKSPRHITPDAAARLRAAATGRAVAVAVTVDADDEALDEIVKTVRPDMLQLHGGETPERVRFLKERYNLPVMKAFSIREAGDLEAIAPYRGIADRFLFDAKPPKGSELPGGNGISFDWNLLAALDADIDYMLSGGLNADNIAEALLKTGAPGIDISSGVECAPGEKDVRLIENFFQAVADANAQPFARRA
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: NUDC_CHRVO
Sequence: MPFELPQQPAPELPERWCVFNGSLLWLQDNQLPAQPPAGCALTGQRFLGIHEGSNLFLADLVGDMPAQAGEWLPLRPALLAMPMAQVQAAARAAQLRQFFHSHRFCGHCATPLAVSADQLGRHCPSCGQVYYPRISPAMMVLVRRGRELLLARSPHFAPGMYSALAGFVEPGETLEECVHRETWEEVGVKVKNLRYAFSQSWPFPHSLMLAFIAEYDGGDIRPQEGEIEDAGWFDIDALPGLPMPISIAHRLIRHACDRIRDLEA
What is the function of this protein?
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.  The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing.  Has preference for mRNAs with a 5'-end purine.  Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.
What are the official names of this protein?
NAD-capped RNA hydrolase NudC, DeNADding enzyme NudC, NADH pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudC subfamily.