PharMolix/UniProtQA huggingface dataset:
Protein: TSAD_CALBD
Sequence: MLVLGIETSCDETSAAIVEDGRKILSNVIYSQIDIHYQFGGVVPEIASRKHVEKISYVVDMAFKQAGLTIDDIDGIAATYGPGLVGSLLVGLSFAKALSYAKRLPFVAVNHIEGHIYANFITYPQLTPPLIVLVVSGGHTNLIILKDFEEYEVVGKTRDDAAGEAFDKIARYLGLGYPGGPAIDKIAKQGDEDKYKYPVADVGGYNFSFSGLKSAVINHVHGLWQRGEEFKIEDVAASFQKTVVSILVEKTINLSLETNIRKIAVAGGVAANSKLRSEFYKKCAEHNIEFFVPEFKYCTDNAAMIASCGYFKLQKGIVSSYRENAVPYINLVSKKS
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CD81_SAGOE
Sequence: MGVEGCTKCIKYLLFVFNFVFWLAGGVILGVALWLRHDPQTTNLLYLELGDKPAPNTFYVGIYILIAVGAVMMFVGFLGCYGAIQESQCLLGTFFTCLVILFACEVAAGIWGFVNKDQIAKDVKQFYDQALQQAVVDDDANNAKAVVKTFHETLNCCGSSTLSALTTSMLKNNLCPSGSSIISNLFKEDCHQKIDELFSGKLYLIGIAAIVVAVIMIFEMILSMVLCCGIRNSSVY
What is the function of this protein?
Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling.  Essential for trafficking and compartmentalization of CD19 receptor on the surface of activated B cells.  Upon initial encounter with microbial pathogens, enables the assembly of CD19-CR2/CD21 and B cell receptor (BCR) complexes at signaling TERMs, lowering the threshold dose of antigen required to trigger B cell clonal expansion and antibody production.  In T cells, facilitates the localization of CD247/CD3 zeta at antigen-induced synapses with B cells, providing for costimulation and polarization toward T helper type 2 phenotype.  Present in MHC class II compartments, may also play a role in antigen presentation (By similarity).  Can act both as positive and negative regulator of homotypic or heterotypic cell-cell fusion processes.  Positively regulates sperm-egg fusion and may be involved in acrosome reaction.  In myoblasts, associates with CD9 and PTGFRN and inhibits myotube fusion during muscle regeneration (By similarity).  In macrophages, associates with CD9 and beta-1 and beta-2 integrins, and prevents macrophage fusion into multinucleated giant cells specialized in ingesting complement-opsonized large particles (By similarity).  Also prevents the fusion of mononuclear cell progenitors into osteoclasts in charge of bone resorption (By similarity).  May regulate the compartmentalization of enzymatic activities.  In T cells, defines the subcellular localization of dNTPase SAMHD1 and permits its degradation by the proteasome, thereby controlling intracellular dNTP levels (By similarity).  Also involved in cell adhesion and motility.  Positively regulates integrin-mediated adhesion of macrophages, particularly relevant for the inflammatory response in the lung (By similarity).
What are the official names of this protein?
CD81 protein.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Note=Associates with CLDN1 and the CLDN1-CD81 complex localizes to the basolateral cell membrane.
Protein: HCAF_ECOSE
Sequence: MSAQVSLELHHRISQFLFHEASLLDDWKFRDWLAQLDEEIRYTMRTTVNAQTRDRRKGVQPPTTWIFNDTKDQLERRIARLETGMAWAEEPPSRTRHLISNCQISETDIPNVFAVRVNYLLYRAQKERDETFYVGTRFDKVRRLEDDNWRLLERDIVLDQAVITSHNLSVLF
What is the function of this protein?
Part of the multicomponent 3-phenylpropionate dioxygenase.  Converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid-dihydrodiol (CI-dihydrodiol), respectively.
What are the official names of this protein?
3-phenylpropionate/cinnamic acid dioxygenase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.
Protein: AROD_BACVZ
Sequence: MQSITIRNTVIGEGLPKIIVPLMAAGEKELLEEIEAVNRLRPDIIEWRADVYEHVDSLDAVKDMLEMLRKAAGATPLLFTFRTHKEGGNKVIDDRFYIELLKTAIETKHIDLADVELFTGEAEVKLIVKTAEDNGVYVVMSNHDFHQTPKKEEIISRLRNMQAYGAHIPKIAVMPQSTEDVFVLLDATHTMKTQYADRPIITMSMAGTGLISRLAGEVFGSACTFGAGKEASAPGQIPVEELRSVLSILNKHM
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: HBB_MESAU
Sequence: MVHLTDAEKALVTGLWGKVNADAVGAEALGRLLVVYPWTQRFFEHFGDLSSASAVMNNPQVKAHGKKVIHSFADGLKHLDNLKGAFSSLSELHCDKLHVDPENFKLLGNMIIIVLSHDLGKDFTPSAQSAFHKVVAGVANALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain, Hemoglobin beta-major chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: Y519_HAEIN
Sequence: MSVLSSILGMVVLIAIAVLLSNNRKAISIRTVVGALAIQVGFAALILYVPAGKQALGAAADMVSNVIAYGNDGINFVFGGLADPSKPSGFIFAVKVLPIIVFFSGLISVLYYLGIMQVVIKVLGGALQKALGTSKAESMSAAANIFVGQTEAPLVVRPYIKNMTQSELFAIMVGGTASIAGSVMAGYAGMGVPLTYLIAASFMAAPAGLLFAKLMFPQTEQFTDKQPEDNDSEKPTNVLEAMAGGASAGMQLALNVGAMLIAFVGLIALINGILSGVGGWFGYGDLTLQSIFGLIFKPLAYLIGVTDGAEAGIAGQMIGMKLAVNEFVGYLEFAKYLQPDSAIVLTEKTKAIITFALCGFANFSSIAILIGGLGGMAPSRRSDVARLGIKAVIAGTLANLMSATIAGLFIGLGAAAL
What are the official names of this protein?
Uncharacterized transporter HI_0519.
What is the protein family that this protein belongs to?
Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TILS_YERPS
Sequence: MNLVTSKPNVLLNPLFAQLGENRHVLVGFSGGLDSTVLLHLLVCLRQQLIPELNIRAIHIHHGLNPQADSWVKHCMQQCDQWKIELKVVRVNIDPRQNGIEAAARTARYQAFSANLAAKEVLLTAQHLDDQCETFLLALKRGSGPAGLSAMAAKMPFAHSQLLRPLLAFSREILENYAQAQQLQWIEDDSNQDDRFDRNFLRLNVLPILNQRWPHFAQATARSAGLCAEQEQLLDELLAENLQQLQGPDRSLSIDGLLQASMAKRAAILRRWLASLGAPMPSQSQLQRLWLEVAMARQDAEPQLMIGTRQVRRFRQHLYLLMPLAEITTNYLPWATVKAAPNSSIIPLLPEPLWLPADLGVLRFVSAGGQAVRPAAVGEEISVRFGLQGDIKIVGRHHSRQSKKVWQELGIPPWQRERIPLLYFGEQLIAAAGVFVTQAGQANENEPCWHLDWDKPLKLG
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLK_CAUVN
Sequence: MDGNHSGGLGLVGDIGGTNARFALVEFDGQDPRLIEPTAYRGEDYGTAEDAIEEYLRKVGVKHPDQAVVAVAGPIDHGQVHMTNLDWRISEDGLRRAGGFRNAKLINDFTAQALAAPRVGPKDLRQIGELPTSGEGDLAILGPGTGFGVAGLVRRHGQEIPLATEGGHVAFAPVDDVEIEVLRALTRRLDGGRVSVERILSGPGMEDLHVDLAAAEGRGVEALTAKQITERAVEGCADSLATVNRFCAILGSTAGDIALTLGARGGVFIAGGIAPRIIDILEKSPFRERFDSKGRLSGFTRSIPTHVILHPHTALIGAAVALTPEGRAAVS
What are the official names of this protein?
Glucokinase, Glucose kinase.
What is the protein family that this protein belongs to?
Belongs to the bacterial glucokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CEMA_CRUWA
Sequence: MAKKKAFIPFFYFTSIVFLPWLISLCCNKSLKTWITNWWNTRQCETFLNDIQEKSVLEKFIQLEDLFQLDEMIKEYPETDLQQFRLGIHKETIQFIKIHNEYRIHTILHFSTNLISFVILSGYSFWAKEKLFILNSWVQEFLYNLSDTIKAFSILLVTDLCIGFHSPHGWELMIGYIYKDFGFAHYEQILSGLVSTFPVILDTIFKYWIFRYLNRVSPSLVVIYHAIND
What is the function of this protein?
May be involved in proton extrusion.  Indirectly promotes efficient inorganic carbon uptake into chloroplasts.
What are the official names of this protein?
Chloroplast envelope membrane protein.
What is the protein family that this protein belongs to?
Belongs to the Cema family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: SYL1_SULTO
Sequence: MSLANFFNEIAFKWQKEWENSKVYEANPETDKPKKFITVAFPYTNSPLHIGHGRTYITADIYARYLRMKGYNVLFPFAFQFTGTPILSISESVKRGDEEIISTFVNIYQIPKEEIEKFSDPTYLAEYFKNNMKNTAKKLGLGIDWRREFTTVDPIFEKFVQWQYRKLMELGYIKREDSPVAYCPRDEFPVGMHDTKGDVEPEITDLDGIYFPSGDYFFIAATPRPETIFGAVALLVNPEADYVIATDSLNRKVIISRQAYDKLKYQISFREEGEKKGKDLVGMIAKNPVTEKEIKVLPSKFVDPSIGTGVVMAVPSHEPLHYIALTELKEEFELIPVIKTDELGELPGVEAVGLAQTRNPAELKDYIDTIYRIEYHKGIMREDLVDLVPNFMKEFVKDKIAGKLVKDAREKTRELLDMLNSRITIYEISNGPVYCRCGAEIVVKVIKGQWFIDYSNPIWKTSVLKSLDKINFIPTDSKKEMEKIIFNLQPRAFTRSRGLGVRLPWDEKEIIDSLSDSTIYTAFYTIVHKLKYPISLLSDKFWDYILLDRGTADEISKELGIPKEQLEEIKSEFKYWYPVDSRHSGRDLIQNHLPYYLFHHFAIFGEKFLPRQIVTNGFIRVGGKKMSKSFGNIYPLNRAIDEYGVETVRIALTSTSSISDDIEFNSNIAKSIAEQLKKIHDLISKLLEIEGVNERRDPDVWLLSIFRRYIEDVDKAYENLDLRTVYMTVYYTIYETIKDYIELTNAKINKDIIKKVISIWLRLMAPITPHLAEELWHKMSNTFVVKEKFPSINEVEYNEKSLLKVEYLRSIIEDVNRLSSELGKEAEKVVIYVNDDNNLRELLKKAIIAIKDRKSLRDFMIENNVDDKTARRIYELANVLPSTIRDLIVTTDIDEEEVIVQNINFLMNKLDLREMIVYSSTDEKAPNILGKKDLALPYKPGIAIL
What are the official names of this protein?
Leucine--tRNA ligase 1, Leucyl-tRNA synthetase 1, LeuRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEC16_YEAST
Sequence: MTPEAKKRKNQKKKLKQKQKKAAEKAASHSEEPLELPESTINSSFNDDSVNRTESDIASKSDVPPVSSSTNISPANETQLEIPDTQELHHKLLNDSDQHDITADSNDLPDNSIVEHDSVITQTKPAMSQEYEETAAHLSSRNPSLDVVAGELHNNNEHTQKIAVSAVEEDSFNEEEGENHDSIIISSLNDATPSQYNHFLPSDGNLLSPELSSGDTPTHNVPLGTKDNEINDDEYCNDKEISLNANNVLPDELSKEEDERLKLETHVSTEEKKQDIADQETAENLFTSSTEPSENKIRNSGDDTSMLFQDDESDQKVPWEEDVKKDFHNENTNNTQESAPNTDDRDKGYEGNEALKKSESCTAADERSYSEETSEDIFHGHDKQVVEGQNDFTGKNIENESQKLMGEGNHKLPLSAEADIIEPGKDIQDQAEDLFTQSSGDLGEVLPWESTDKNADVTSKSQEKHEDLFAASGNDEKLPWEVSDGEVSSGKTENSMQTSTEKIAEQKFSFLENDDDLLDDDDSFLASSEEEDTVPNTDNTTNLTSKPVEEKKASRYKPIIEEEAGMRQEQVHFTNTTGIVTPQQFHGLTKTGLGTPNQQVSVPNIVSPKPPVVKDNRSNFKINEEKKKSDAYDFPLEIISESSKKGHAKPVAVPTQRFGSGNSFSSLDKPIPQSRKGSNNSNRPPVIPLGTQEPRSSRTNSAISQSPVNYAFPNPYKIQQLQQAPIQSGMPLPNTNIPPPALKVETTVSAPPIRARGVSNASVGSSASFGARHATQYGLNNGVPPVSPYGQATINLPTANKYAPVSPTVQQKQYPSVVQNLGASAVNTPNFVKTHRGHTSSISSYTPNQNEHASRYAPNYQQSYQVPYTSQPVGPVAGNSSYQSQTRSSYAVPMMPQAQTSASIQPHANIQPPTGILPLAPLRPLDPLQAATNLQPRASNITAANSLPLANLPLAENILPEIITHRATSSVAPPRQENNPIKIDNEALLRRQFPIFHWSAANKVVYAVPPIPDQSQYMISSSIVQEIKVTPIDQIIKPNDMLKSFPGPLGSAKLKKKDLTKWMETTIKSISENESSTDMTIWQLLEMKLNDKVNWKNISKLLYNSDELLMYLSQPFPNGDMIPNAYRLDINCQMRVLAFLQTGNHDEALRLALSKRDYAIALLVGSLMGKDRWSEVIQKYLYEGFTAGPNDQKELAHFLLLIFQVFVGNSKMAIKSFYTNNETSQWASENWKSIVAAVLINIPENNEDPLLIPPVVLEFLIEFGIFLTKKGLTAAASTLFIIGNVPLSNEPVMADSDVIFESIGNMNTFESILWDEIYEYIFSYDPKFKGFSSILPQKIYHASLLQEQGLNSLGTKYTDYLSSSVRKLPKKDILTINLTRELSEVASRLSESNTGWLAKPKLSSVWGQLDKSFNKYIGGDDIDALNKKNDKKKVFDGFTPGSSANSSTVDLTQTFTPFQAQVTSQSYVDTTALLHNAHNVPSHSVLHSKPSNVSKGLVEANLPYTHRIGDSLQGSPQRIHNTQFAAAEPQMASLRRVRTDQHTNEKALKSQQILEKKSTAYTPQFGQNHSVPMEKSNSNVPSLFADFPAPPKLGTVPSNYVSSPDLVRRESIISTGSEFLPPPKIGVPTKANSSQGSLMYSPSVEALPIDPVVPQVHETGYNDFGNKHSQKSMPEDESHTSHDNSNADQNTLKDSADVTDETMDIEGPGFNDVKNLLPMEPNHQPTSTVNPIQTISDDIQPILQTNVEVRGTDASKMENSLPSIENERSSEEQPENISKSASSAYLPSTGGLSLENRPLTQDENSISETVQSTYLPAGSISMEAKPISQVQDVPRNVNNKASKLVEQHMAPPKPKSTDATKMNYSPYVPQSTAASADGDESTILKTSPAIYARTHQAHASNPSQYFPLVNQANETASFELSESTSQAQSNGNVASENRFSPIKKAEVVEKDTFQPTIRKASTNQYRAFKPLESDADKYNDVIEDESDDDNMSTDEAKNRKEEKKNVNMKKETKPSNKDIDDKSNGWFGWLKKDTGDKKVYKAKLGHKNTLYYDEKLKRWVNKDATEEEKQKIIESSAPPPPPIVKRKDGGPKTKPRSGPINNSLPPVHATSVIPNNPITGEPLPIKTSPSPTGPNPNNSPSPSSPISRISGVNLTSKKANGLDDLLSLAGGPKPASTRRKKKTARGYVNVMDNIQ
What is the function of this protein?
Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules.  Also involved in autophagy.
What are the official names of this protein?
COPII coat assembly protein SEC16, Protein transport protein SEC16.
What is the protein family that this protein belongs to?
Belongs to the SEC16 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=On the endoplasmic reticulum and on vesicles which bud from it.
Protein: ISPH_PARDP
Sequence: MDKKPPLTLYLAAPRGFCAGVDRAIKIVEMALQKWGAPVYVRHEIVHNKFVVDSLRDKGAVFVEELDDVPSDRPVIFSAHGVPKAVPAEARRREMVFVDATCPLVSKVHVEAERHHAEGLQMVMIGHAGHPEVLGTMGQLPEGEVLLVETVEDVARIEPRDPGRLAFITQTTLSVDDTAAIVAALQARFPGIRGPAKEDICYATTNRQASVKAIAGRIDALLVIGAPNSSNSRRLVEVGSAAGCAYSQLVMRADQIDWRAIAGARAVGVTAGASAPEVLVDEVVAAFHARYDLTVEMVETARENVEFKVPRVLREA
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: RBSD_ECO45
Sequence: MKKGTVLNSDISSVISRLGHTDTLVVCDAGLPIPKSTTRIDMALTQGVPSFMQVLGVVTNEMQVEAVIIAEEIKQHNPQLHETLLTHLEQLQKHQGNTIEIRYTTHEQFKQQTAGSQAVIRSGECSPYANIILCAGVTF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRY_KOGSI
Sequence: MFRIVNGEDYSPAVQQRNILDFGKAPSLLWTDNGSSNDRCDTGGNGRESGQDRVKRPMNAFIVWSRDQRRKVALENPQMQNSEISKRLGYDWKMLTEAEKQPFFEEAQRLRAMHRDKYPGYKYRPRRKPKRPQKLLPADSSVLCSRMHIEETLYPFTYKDGCAKATRSRMESQLSNSQPTNISSSLLPQEHPSSWTILRHNRVTQATQTCGRPLLL
What is the function of this protein?
Transcriptional regulator that controls a genetic switch in male development.  It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells.  Involved in different aspects of gene regulation including promoter activation or repression.  Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.  SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending.  Also involved in pre-mRNA splicing (By similarity).  In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity).
What are the official names of this protein?
Sex-determining region Y protein, Testis-determining factor.
What is the protein family that this protein belongs to?
Belongs to the SRY family.
What are the subcellular locations of this protein?
Nucleus speckle. Cytoplasm. Nucleus.
Protein: RNFH_TOLAT
Sequence: MPDQIQIEVVYALPMRQTTLTLKINTGSSVEDAIRESGILARHPEIDLAVNKVGLFGRAVALSTRLERPTRIEIYRPLLADPKEIRRQRAEKAKLQSLK
What are the official names of this protein?
Protein RnfH.
What is the protein family that this protein belongs to?
Belongs to the UPF0125 (RnfH) family.
Protein: CCL11_BOVIN
Sequence: MKVSAVLLCLLLTATLCSIQVLAQPASIPTICCFNMSKKKISIQRLQSYRKITSSKCPQKAVIFNTKQNKKICVDPQEKWVQNAMEYLNQKSQTLKS
What is the function of this protein?
In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils (a prominent feature of allergic inflammatory reactions), but not lymphocytes, macrophages or neutrophils (Probable).  Attracts eosinophils in vitro but is not responsible for eosinophilia in the ovary (PubMed:15916812).  Binds to CCR3 (By similarity).
What are the official names of this protein?
Eotaxin, C-C motif chemokine 11, Small-inducible cytokine A11.
What is the protein family that this protein belongs to?
Belongs to the intercrine beta (chemokine CC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYV_DEHMC
Sequence: MAQCSDLPEMAKAYEAAEVEKKWYQYWMEKSYFKPNPNSDKKPFVIIMPPPNVTGELHLGHALTATLEDIMIRWHRMQGEPTLWLPGVDHAGIAAQVVVERELAKQGKTRQQLGRELFLEKMWEWVNPCREKIRHQHMRLGASCDWDRETFTLDAGPVKAVREIFTNLYEKGLIYKGERIINWCPRCGTAVSDLEVDHKDLAGHIWHLRYPLEDGSGFVTVATTRPETMQGDTAVAIHPDDTRYAGMVGKNVVLPIMNRRIPVIADEAVDMAFGTGAVKVTPAHDPNDFEMGLRHNLPMITIQNRDTTMNENAGPCSGMTAKACREYVVSEMKSLGLLLRIEDYIHSVGHCQRCSAVIEPMVSKQWFVKMEPLAKPALEAVNSGRIQILPERFNKVYQNWMENIRDWCISRQLWWGHRIPVWYCPCGEMIVAKVDPTVCPKCGGTELEQDPDVLDTWFSSGLWPHSTLGWPDQTEDLKRFYPGTVMETAYDIIFFWVARMIVMGMEDMNEVPFRTVYLHGLIRDDKGEKMSKTKGNVIDPLKVIDQYGTDALRFAVTFGTSPGNDSKLGQTKLEAARNFANKLWNASRFVIMNLGEAKELTPEAELPLEDRWIISRMNRVTADVTRLMEEFQFGEAQRVLQDFIWGEFCDWYIELAKVRLRDEASVSPRPVLVRVLSSILRLLHPYMPFITEELWSYLRPYLPESLRETDIIVAPYPAADKTCFDEQAESVMGSLVEIVRSLRNLRAEHNVEISRYIQANIYAGDMASVLGNYLGAVETLSRARPVNILPGHYSGASTATEVVLVLTGIEVVVPMSTMVDLEVEAKRVKAEISELEIQIERLSTRLSDEQFLAKAPQAVVDKERIKLEGYIEKVSRLKSA
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSB_BORBU
Sequence: MADINSLVLSGRLTRDSELSYTESGMAVLRFSIANNRRMKKNDEWIDYPQYFDCVIFSKRAESLNDYLKKGKQVVVSGSLKYESWQDRNTGDKRSKVNIFVDNLQMFSSGSNTIQMQDSDVNSLTNHKKEDVVKDIDIVDDKFSEDIPF
What are the official names of this protein?
Single-stranded DNA-binding protein, SSB.
Protein: ORN_PARXL
Sequence: MTDILASTEQPPLVRSDMNLVWLDMEMTGLEPDSDRIIEIAVVVTNSTLDRMVEGPVLAIHQSDETLAGMDQWNQNTHGRSGLIDRVKASTVSEADATEQIRDFLSVYVPPGKSPMCGNSICQDRRFMARWMPELERFFHYRNLDVSTLKELCRRWQPAIYKGFQKRAMHTALADIHESIDELKYYREHFLIPSAPDAANGAEKAAE
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_GEOKA
Sequence: MARIAGVDIPRDKRVVISLTYIYGIGKPTAQKILKEAGVSEDTRVRDLTEEELGRIREIVGRLKVEGDLRREVSLNIKRLMEIGCYRGLRHRRGLPVRGQNTKNNARTRKGPRRTVANKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: LT4R2_HUMAN
Sequence: MSVCYRPPGNETLLSWKTSRATGTAFLLLAALLGLPGNGFVVWSLAGWRPARGRPLAATLVLHLALADGAVLLLTPLFVAFLTRQAWPLGQAGCKAVYYVCALSMYASVLLTGLLSLQRCLAVTRPFLAPRLRSPALARRLLLAVWLAALLLAVPAAVYRHLWRDRVCQLCHPSPVHAAAHLSLETLTAFVLPFGLMLGCYSVTLARLRGARWGSGRHGARVGRLVSAIVLAFGLLWAPYHAVNLLQAVAALAPPEGALAKLGGAGQAARAGTTALAFFSSSVNPVLYVFTAGDLLPRAGPRFLTRLFEGSGEARGGGRSREGTMELRTTPQLKVVGQGRGNGDPGGGMEKDGPEWDL
What is the function of this protein?
Low-affinity receptor for leukotrienes including leukotriene B4.  Mediates chemotaxis of granulocytes and macrophages.  The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system.  The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3.
What are the official names of this protein?
Leukotriene B4 receptor 2, LTB4-R 2, LTB4-R2, LTB4 receptor JULF2, Leukotriene B4 receptor BLT2, Seven transmembrane receptor BLTR2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: COAX_CERS5
Sequence: MLLAIDCGNTNTVFSIWDGTQFLATWRIATDHKRTADEYHVWLSTLLSLTRIEARITEAVISSTVPRVVFNLRVLCNRYYDCRPLVVGKPECRLPVAPRVDQGTTVGPDRLVNTVAGYHLHGGNLIVVDFGTATTFDVVDADGAYIGGVIAPGVNLSLEALHMAAAALPHVDVTKPPHAIGTNTVACIQSGVYWGYIGLVEGIVRQIRLERHAPMKVIATGGLAPLFDQGFDLFDKVEDDLTMQGLVLIHQYNKELE
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEG_SYNSC
Sequence: MQGHVTDQQTRLSEALKRRAAEEGFNPVGIARIPGSPRLQLRTKALQRWLDHGHQADMAWMAAPRRRDPRLLLDGANSVLAVGLNYYVDAQPSPGSLKVARYGWGRDYHRVVDQRLRRIGRWLSEQRPDCGWRACVDATPLLDKAWAEEAGLGWIGKHSNLIHPERGSWMVIGHLLTTEPLNADPPARSLCGRCSACIDACPTHAIREPFVVDARRCLAFHTIENREDDLPENIRAALGSWVAGCDICQDVCPWNHRSLPQSNDPDMQPRPWLLNLHKEEIQTWDDSVWEQKLRGSALRRIKPWMWRRNAAAAQPDPTPTL
What is the function of this protein?
Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
What are the official names of this protein?
Epoxyqueuosine reductase, Queuosine biosynthesis protein QueG.
What is the protein family that this protein belongs to?
Belongs to the QueG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WHIA_ALKMQ
Sequence: MSYSSNTKNELARIEGEQSCCVRAELAALIRMSGTLQLVGSQKLNIKVTTENPAIARRLFKIIKKQYNIHAEVMIRRNARLKKNNYYLLVITHSMGSSEVLADLGIMKKVDDSFDITYRIPQELTQNRCCKRAYLRGAFLGGGSVSDPEKTYHLEFVTHHKELSEGLRDLINSFDLNAKVVERKGNYVVYLKEGDQVVDLLNIVGAHSALLDLENIRVYKEMRNNVNRIVNCETANLSKTVDASIRQIQNIQYIEGSIGINRLPDNLREVAELRVEYQDATLKELGEMINPPIGKSGVNHRLRKLDQIADRERGKSI
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: ODAD4_BOVIN
Sequence: MADPENEVLRSTFPSYMAEGERLYLCGEFAKAAHSFSNALHLQSGDKNCLVARSKCFLKMGELEKSLEDAEASLQGDPTFCKGILQKAETLYTMGDFEFALVFYHRGYKLRPDREFKVGIQKAQEAINNSVGSPSSIKLENKGDLSFLSKQAESMRAQQKPHPVRQLIHHPKRESKRKGSLKSEKIVRQLLGELYVDKEYLEKLLLDEDLIKGTIKHGLTVEDLIMTGINYLETRSDFWRQQKPIYARERDRKLMQEKWLRDRKRRPSQTARYILKSLEDIDMLLTSGSAEGSLQKAEKVLKKVLEWNKEEVPNKDELVGNLYSCIGNAQIELGQMVAALQSHRKDLEIAKEYDLPDAKSRALDNIGRVFARVGKFQQAIDTWEEKIPLAKTTLEKTWLFHEIGRCYLELDQAWEAQSYGEKSQQCAEEEGDMEWQLNASVLVAQAQVKLRDFESAVNNFEKALERAKLVHNNEAQQAIINALDDANKGIIEELKKTNYREILKEKKEKENATMLDGQTRTAKEKETRKTKDEPEKVMKQWVQEQTEKQLEGVLSKETLGVTARQPEQRQREDPEKASWRKELGAKERGPGDTAKGQFGEAGRTEQNREETREIYRRPSELDQNLSDESSPRESEGLEKRLSKTDGGELEALGKTESGEIKEMEITENSEKIEKDEKEDEPIE
What is the function of this protein?
Component of the outer dynein arm-docking complex (ODA-DC) that mediates outer dynein arms (ODA) binding onto the doublet microtubule.  Plays an essential role for the assembly of ODA-DC and for the docking of ODA in ciliary axoneme.
What are the official names of this protein?
Outer dynein arm-docking complex subunit 4, Tetratricopeptide repeat protein 25, TPR repeat protein 25.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme.