PharMolix/UniProtQA huggingface dataset:
Protein: ATP8_SALFO
Sequence: MPQLNPAPWFAILVFSWLVFLTVIPPKVLGHTFTNEPTSQSTEKTKPEPWNWPWH
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: GPMA_NEIMA
Sequence: MELVFIRHGQSEWNAKNLFTGWRDVKLSEQGLAEAAAAGKKLKENGYEFDIAFTSVLTRAIKTCNIVLEESDQLFVPQIKTWRLNERHYGRLQGLDKKQTAEQYGDEQVRIWRRSYDTLPPLLDKDDEFSAHKDRRYAHLPADVIPDGENLQVTLERVLPFWEDQIAPAILSGKRVLVAAHGNSLRALAKHIEGISDEDIMGLEIPTGQPLVYKLDDNLKVIEKFYL
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: RS20_AERHY
Sequence: KRALQSEKRRQHNASRRSMTRTYLKKVIAAIASGDKAAATAAFAVAQPIMDRMATKGLIHKNKAARHKSRLS
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: PDXT_BACC7
Sequence: MVKIGVLGLQGAVREHVKSVEASGAEAVVVKRIEQLEEIDGLILPGGESTTMRRLIDKYAFMEPLRTFAKSGKPMFGTCAGMILLAKTLIGYDEAHIGAMDITVERNAFGRQKDSFEAALSIKGVGEDFVGVFIRAPYVVNVADNVEVLSTHGDRMVAVRQGPFLAASFHPELTDDHRVTAYFVEMVKEAKMKKVV
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: SYC_ECO81
Sequence: MLKIFNTLTRQKEEFKPIHAGEVGMYVCGITVYDLCHIGHGRTFVAFDVVARYLRFLGYKLKYVRNITDIDDKIIKRANENGESFVALVDRMIAEMHKDFDALNILRPDMEPRATHHIAEIIELTEQLIAKGHAYVADNGDVMFDVPTDPTYGVLSRQDLDQLQAGARVDVVDDKRNPMDFVLWKMSKEGEPSWPSPWGAGRPGWHIECSAMNCKQLGNHFDIHGGGSDLMFPHHENEIAQSTCAHDGQYVNYWMHSGMVMVDREKMSKSLGNFFTVRDVLKYYDAETVRYFLMSGHYRSQLNYSEENLKQARAALERLYTALRGTDKTVAPAGGEAFEARFIEAMDDDFNTPEAYSVLFDMAREVNRLKAEDMAAANAMASHLRKLSAVLGLLEQEPEAFLQSGAQADDSEVAEIEALIQQRLDARKAKDWAAADAARDRLNEMGIVLEDGPQGTTWRRK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XPT_STRPF
Sequence: MQLLEERILTDGNILGENILKVDNFLTHQVDYRLMKAIGKVFAQKYAEAGITKVVTIEASGIAPAVYAAEAMDVPMIFAKKHKNITMTEGILTAEVYSFTKQVTSTVSIAGKFLSKEDKVLIIDDFLANGQAAKGLIEIIGQAGAQVVGVGIVIEKSFQDGRRLIEDMGIEVTSLARIKNFENGNLNFLEADA
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPH_HAEDU
Sequence: MRPNHRENNQIRPVKITRHYTRYAEGSVLIEFGETKVLCNASIEESVPRFLKGQQQGWVTAEYGMLPRATHSRNQREAAKGKQSGRTMEIQRLIARALRAVVDLEALGERTITIDCDVIQADGGTRTAAITGACVALQDAIHKLIADGVLKTNPLKGLVAAISVGIVENEAVCDLEYVEDAKAETDMNVVMVEDGRLVEVQGTAEGKPFSHMELLQLLDLADQGINQLFEVQRQALAE
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: TAUB_BURCH
Sequence: MSTLEVRQVSVAYPGERGRPTTQALAQVDLRIDAGEFVVALGASGCGKTTLLNCMAGFVAPTTGDVRVDGVPIAGPGADRGVVFQKYALLPWLDVLDNVALGLRFARVSKAEREARAREMLTLVGLERHAHARVYELSGGMQQRVGIARALASDPRVLLMDEPMGALDAMTRGTMQALVLDVWARTGKTVFFITHDVEEALFLATRLVVMTPGPGRIAETFELPFARRYVESRDARAVKSSPDFIGWRERLIAYLHRDEAVAEPA
What is the function of this protein?
Part of the ABC transporter complex TauABC involved in taurine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Taurine import ATP-binding protein TauB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Taurine importer (TC 3.A.1.17.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ALGL_PSEPW
Sequence: MTAFKRIFSPALLVLALYGGAAHAALVPPQGYYEGIEKIKTSDGNFRCESAPKPFTGALQFRSKYEGSDKARATLNRDSEQAFRDSTKDITTLERGVAKMVNQYMRDGRPAQLDCTLTWLGTWARADALMSTNYNHTGKSMRKWALGSMSGSWLRLKFSNSQPLAAHQAEAELIEKWFARLAEQTVRDWSNLPLEKINNHSYWAAWSVMATAVATDRRDLFDWAVKEYKVGANQIDDQGFLPNEIKRKQRALAYHNYALPPLAMIASFAKANGVDLRSENNFALQRLGEGVLYGARDPRHFAERAGEKQDMKDLKVDGKYAWLEPWCALYQCVGDTLERKHRMQPFDSFRLGGNLTRVYDPSAQSKK
What is the function of this protein?
Catalyzes the depolymerization of alginate by cleaving the beta-1,4 glycosidic bond between two adjacent sugar residues via a beta-elimination mechanism.  May serve to degrade mislocalized alginate that is trapped in the periplasmic space.
What are the official names of this protein?
Alginate lyase, Poly(beta-D-mannuronate) lyase.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 5 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: YUTC_BACSU
Sequence: MKRTAVSLCLLTGLLSGCGGAGLDNAQNVRNQTQNQTKPIHVSDRNEAFNRHNENEQFGYVRYQKEQFDGEQQKTPVMNREETAHMISSLTVQLPHIQDAATLVTDREALVVYKTDSKNRELTADQVKKTAASVIPRYYHVYISDNPNHMQSVENYSNLGSGSRDIREIMSGTIQEMKTSPQGSPVSENENANGETRQDMKIDRNDKNAR
What are the official names of this protein?
Uncharacterized lipoprotein YutC.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: ISPD_LEPBL
Sequence: MKSLFLSEKIYVLILAGGTGTRMGSEIPKQFLEFSNEPILIHTLKKFQSWKKQKQIVLVSHPEFISETESICSPFLENQDCIIEGGETRHGSMLRGLSALTIQSEDILLIHDAARPFVLLKELDLLCENIRENGISTLASRTSETVLEESNGKTSSFLDREHIWFMKTPQGIRGDILKELLTLPMDPIPTDLCSWALTAGKKSSIVESHPFNLKITRKEDLELAEFYSDLFEKLR
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: RS2_GEOSM
Sequence: MSNITMKELLEAGVHFGHQTKRWNPKMKPYIFGARNGIYIIDLQKTVRLFKNAYSFVTDAAQAGETVLFVGTKKQAQDSVAEEAQRCGQFYVNDRWLGGMLTNFSTVKQSIDRLKRLDAMIADGTIEAYTKKEQLKLAKEREKLEKTLGGIKGMGKVPGVLFVVDPKNEEIAVSEAKKLGIPVVAIVDTNCDPDDINYVIPGNDDAIRAIRLLTSKMADAVLEGGQARNARLQTGAEEEFSTEGEEVVEETPAEA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: TRUB_SHEB9
Sequence: MARRPKGRFIDGIVLLDKSTGMSSNFALQRVKRFFNANKAGHTGALDPLATGMLPVCLGEGTKFSQHLLDADKRYLVTAKLGERTDTSDSDGEVVQTRAIDFTEAQLLTALDFFRGETQQVPSMYSALKYQGQPLYKYAREGIEVPRESRPITVFELNFIGLEGDELTLDIHCSKGTYIRTIIDDLGEMLGCGAHVIMLRRTQVAQYPYARMVSLEQLEALVAQAHEQQIDPSVLLDPLLLPMDTAVADFPEVNVPDAIAPYLMQGQAVRVPVNADLKTDELVRITLGDIRRFVGIGTMNEDGLLAPKRLIVIHDEPAETD
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: YBEY_NAUPA
Sequence: MIDFDNRTDYEFDINKLNDIYNLLTDKDIELILTDDEEIKELNSQFRNKDKATDVLSFPLEAMPGMPLGSIVISIDTAKKGAEEFGHSVDDEIRLLFLHGLLHLLGYDHETDNGEMRAKEEEIIKKLNLPSSLIVRNED
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_RICRO
Sequence: MSILHATILTVFPEMFPGTLGHSLAGQALNKNIWSYDVINIRDFGLTKHKNIDDEAYGGGNGLIMRPDVLGSSIDHALALNPNAEMYYPSPRGRVFTQSFAKEMLKNKNLIFLCGRYEGIDERVIEEYNVKEISVGDYILSGGEIPTLTILDCLIRLLPGVLMNQNTLSSESFEEDGEFKGGLECSLYTRPEIWRNRAVPSVLLSGNHRLINEWKKAQSHMITKLRRPELLKDL
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_RUEST
Sequence: MRHARGYRRLNRTHEHRKALFSNMAGSLIEHEQIKTTLPKAKELRPIIEKMITLAKRGDLHARRQAASKLKEDKDVAKLFDVLGPRYKDRQGGYVRILKAGFRYGDMAPMAIIEFVDRDVSAKGAADKARLAEIEAVEDEE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: PPAF_SOYBN
Sequence: MGVVEGLLALALVLSACVMCNGGSSSPFIRKVEKTVDMPLDSDVFAVPPGYNAPQQVHITQGDLVGKAVIVSWVTVDEPGSSEVHYWSENSDKKKIAEGKLVTYRFFNYSSGFIHHTTIRNLEYKTKYYYEVGLGNTTRQFWFVTPPEIGPDVPYTFGLIGDLGQSFDSNKTLSHYELNPRKGQTVLFVGDLSYADNYPNHDNIRWDSWGRFTERSVAYQPWIWTAGNHENHFAPEIGETVPFKPYTHRYHVPYKASQSTSPFWYSIKRASAHIIVLASYSAYGKYTPQYKWLEKELPKVNRTETPWLIVLMHSPWYNSYNYHYMEGETMRVMYEPWFVQYKVDVVFAGHVHAYERSERVSNVAYNIVNGLCAPVNDKSAPVYITIGDGGTLEGLATNMTEPQPKYSAFREASFGHAIFDITNRTHAHYSWHRNQDGVAVEADSLWSFNRYWHPVDDSTAHVSH
What are the official names of this protein?
Purple acid phosphatase, Zinc(II) purple acid phosphatase.
What is the protein family that this protein belongs to?
Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.
What are the subcellular locations of this protein?
Secreted.
Protein: MIAB_SALPK
Sequence: MTKKLHIKTWGCQMNEYDSSKMADLLDATHGYQLTDVAEEADVLLLNTCSIREKAQEKVFHQLGRWRLLKEKNPDLIIGVGGCVASQEGEHIRQRAHYVDIIFGPQTSHRLPEMINSVRGDRSPVVDISFPEIEKFDRLPEPRAEGPTAFVSIMEGCNKYCTYCVVPYTRGEEVSRPSDDILFEIAQLAAQGVREVNLLGQNVNAWRGENYDGTTGTFADLLRLVAAIDGIDRIRFTTSHPIEFTDDIIEVYRDTPELVSFLHLPVQSGSDRVLNLMGRTHTALEYKAIIRKLRAARPDIQISSDFIVGFPGETTDDFEKTMKLIADVNFDMSYSFIFSARPGTPAADMVDDVPEEEKKQRLYILQERINQQAMAWSRRMLGTTQRILVEGTSRKNIMELSGRTENNRVVNFEGTPEMIGKFVDVEITDVYPNSLRGKVVRTEDEMGLRVAETPESVIARTRKENELGVGFYQP
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBL_PROMT
Sequence: MQVNPNPNKVPVELNRTSLYLGLLLVFVMGILFSSYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: GALT1_PIG
Sequence: MRKFAYCKVVLATSLIWVLLDMFLLLYFSECNKCDEKKERGLPAGDVLEPVQKPHEGPGEMGKPVVIPKEDQDKMKEMFKINQFNLMASEMIALNRSLPDVRLEGCKTKVYPDNLPTTSVVIVFHNEAWSTLLRTVHSVINRSPRHMLEEIVLVDDASERDFLKRPLESYVKKLKVPVHVIRMEQRSGLIRARLKGAAVSKGQVITFLDAHCECTVGWLEPLLARIKHDRKTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKTFFYIISPGVTKVDYGDISSRLGLRHKLQCRPFSWYLENIYPDSQIPRHYSSLGEIRNVETNQCLDNMARKENEKVGIFNCHGMGGNQVFSYTANKEIRTDDLCLDVSKLNGPVTMLKCHHLKGNQLWEYDPVKLTLQHVNSNQCLDKATEEDSQVPSIRDCSGSRSQQWLLRNVTLPEIF
What is the function of this protein?
Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor (PubMed:8748160).  Has a broad spectrum of substrates such as apomucin-, MUC5AC-, MUC1- and MUC2-derived peptides (By similarity).
What are the official names of this protein?
Polypeptide N-acetylgalactosaminyltransferase 1, Polypeptide GalNAc transferase 1, GalNAc-T1, pp-GaNTase 1, Protein-UDP acetylgalactosaminyltransferase 1, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
What are the subcellular locations of this protein?
[Polypeptide N-acetylgalactosaminyltransferase 1]: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Polypeptide N-acetylgalactosaminyltransferase 1 soluble form]: Secreted.
Protein: NM111_CHAGB
Sequence: MNGTTSPIAARSKRKEPPHTVDGRHPKHHRTNGEVAPAADNTPDNQDEFEGEFGVELEEYEDARLPAVLPTGPDTAEWQATIQRVVRNVVSIRFCQTCSFDTDPALTSEATGFVVDAERGYILTNRHVVGSGPFWGYCIFDNHEEVDAYPVYRDPVHDFGILKFDPKAIKYMPVDALPLRPDLAKVGIEIRVVGNDAGEKLSILSGVISRLDRNAPEYGEGYSDFNTCYYQASAAASGGSSGSPVVNMDGYAVALQAGGRADGAATDYFLPLDRPLRALKCLQEGNPITRGDIQCQFVLKPFDECRRLGLTPEWEAQIRKAFPKETNMLVAEIVLPEGPSHKKAEEGDVLIKVNGELLTQFIRLDDILDSSVGKPVKLLLLRGGEEIEVEIEVGDLHSITPDRFVSVAGGSFHSLSYQQARLYGVACKGVFVCEAGGSFRFDNAENGWLIQTVDHKKTPDLETFIEVMKGIHDKARVVVTYKHLRDLHTLNTTILHIDRHWSKKMKLAVRNDETGLWDFTNLADPLPPVAPIPRKADFIQLEHTSHPAVADLVRSFVHVSCVMPVKLDGFPKNRKWGMGLVIDADKGLVVISRAIVPYDLCDITVTIADSIVVEGKVVFLHPLQNYAIIQYDPKLVDAPVLSARLSSQEITQGASTYFIGYNRIGRIVHAATTVTEIFAVTIPANSGAPRYRAVNVDAITVDTSLSGQCGSGVLVAQDGTVQALWLTYLGERNPSTHRDEEYHLGLATPTLLPVVEQIQRGVDPKLRMLSVEFRAIQMSQARLMGVSEEWIQKVSVANTAHHQLFMVTKRTFERNEQEEAAALLEGDVVLSLNGKIITKISDLDIMYSNEQLDAVLVRNCEELSLKLDTVAADDVETTRAVSFCGAIFHAPHHAVRQQISKLFSEVYVSARTRGSPSYQYGLAPTNFITHVNGKPTPDLEAFLAEVVKIPDNTYFRLRAMSFDSVPWVVTMKKNDHYFPTMELIKDPKEECGWRRITYEGGKVIQGEGPDGVVGSAGEITDMDVDADVCG
What is the function of this protein?
Nuclear serine protease which mediates apoptosis.
What are the official names of this protein?
Pro-apoptotic serine protease NMA111.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1C family.
What are the subcellular locations of this protein?
Nucleus.
Protein: US08_HCMVA
Sequence: MRRWLRLLVGLGCCWVTLAHAGNPYEDDDYYYYREDEPRQHGEPNYVAPPARQFRFPPLNNVSSYQASCVVKDGVLDAVWRVQGTFYPEKGIVARVGWSGRRGRKWGRLHAPECLVETTEAVFRLRQWVPTDLDHLTLHLVPCTKCKPMWCQPRYHIRYFSYGNSVDNLRRLHYEYRHLELGVVIAICMAMVLLLGYVLARTVYRVSSAYYLRWHACVPQKCEKSLC
What are the official names of this protein?
Unique short US8 glycoprotein, Protein HXLF4, gpUS8.
What is the protein family that this protein belongs to?
Belongs to the cytomegalovirus US6 family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein.
Protein: VE7_HPV11
Sequence: MHGRLVTLKDIVLDLQPPDPVGLHCYEQLEDSSEDEVDKVDKQDAQPLTQHYQILTCCCGCDSNVRLVVECTDGDIRQLQDLLLGTLNIVCPICAPKP
What is the function of this protein?
Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle.  Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication.  E7 protein has both transforming and trans-activating activities.  Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes.  Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation.  Also plays a role in the inhibition of both antiviral and antiproliferative functions of host interferon alpha.  Interaction with host TMEM173/STING impairs the ability of TMEM173/STING to sense cytosolic DNA and promote the production of type I interferon (IFN-alpha and IFN-beta).
What are the official names of this protein?
Protein E7.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E7 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=Predominantly found in the host nucleus.
Protein: GLT2_ARATH
Sequence: MTTLQISSSLFRSFLLVICVFVIPSLSSDSDPLQDFCVGDLKASPSINGFPCKSSVSASDFFFSGLGGPLNTSTPNGVAVSPANVLTFPGLNTLGLSMNNVEFAPGGVNPPHSHPRATEAGVVIEGSVFVGFLTTNNTLFSKVLNAGEMFVVPRGLVHFQWNVGKVKARLITSFNSQLPGSAVLPSTLFGSNPTIPNAVLTKTFRTDDVTVNKLKSKFAV
What is the function of this protein?
May play a role in plant defense.  Probably has no oxalate oxidase activity even if the active site is conserved.
What are the official names of this protein?
Germin-like protein subfamily T member 2.
What is the protein family that this protein belongs to?
Belongs to the germin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: Y6G7_ENCCU
Sequence: MIGRMVGLEPSSRSGVLEECRECRAIVMKGDGVQTPLHKGDSILGGEGACLMRYAAWTLISAVDVVYCSLETRESVSLTFNPDGQVIVVPFMFKGYNIAALPTTKFGDLKKDTKQIENVVSFLRSDICYAVWEFLVSSVQYKDDDRFERLFDERMRGYLRNISEGTSKVYMRGNKTFSELLEMVCGRMLECSGRVAGGGA
What are the official names of this protein?
UPF0329 protein ECU06_1670.
What is the protein family that this protein belongs to?
Belongs to the UPF0329 family.
Protein: MURC_BACAN
Sequence: MTVYHFVGIKGTGMSSLAQILHDMKHTVQGSDYEKRFFTQTALEKRNISILPFDKSNVKEGQVIIAGNAFPDTHEEIVAAKELNIPVHRYHHFLGDLMNQYTSVAVTGAHGKTSTTGLLAHVMQGAHPTSYLIGDGTGHGVENSKYFVFEACEYRRHFLSYNPDYAIMTNIDFDHPDYFTDINDVFSAFQEMALQVKKGIIACGDDEELQKIQAKVPVIFYGFGEDNDFQARNIQKRTDGTIFDVFVRNTYYDTFKITGYGNHSVLNALAVIALCHYENVDVEAVKHQLTTFEGVKRRFNEKPMGEQVIIDDYAHHPTEINATIEAARQKHPEREIVAVFQPHTFSRTEKFLDEFAESLSKADQVYLCDIFGSARENKGELTIEDLQKRIDGAELITDTTTDVLKKHKNGVLIFMGAGDIQKFEAAYVKEVQVAEK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSA_PHOLL
Sequence: MSIEINNISKYFGRTQVLSDITLNVFSGEMVALLGPSGSGKTTLLRIIAGLEQQTAGKLSFHGQDVSRMHAKDRQVGFVFQHYALFRHMTVFDNVAFGLTVLPRRRRPNMAAIRRKVMELLEMVQLTHFAERYPSQLSGGQKQRVALARALAVEPQILLLDEPFGALDAQVRMELRRWLRQLHEELKFTSVFVTHDQEEAMEVADRVVVMRQGNIEQVGTPQEVWRYPASRFVMEFLGEVNHFSGEIKGSQLLIGGQHLPLNVTPIHQGNVDVFLRPWDIMMNSQPTLSSPLPVQVTEVSPRGHFWQLSVQPLGWHHESVAVVWFDETSVPTRGNRYFIGGTEARLYAGDKQLQTLSLAQTA
What is the function of this protein?
Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Sulfate/thiosulfate import ATP-binding protein CysA, Sulfate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: OBG_DESPS
Sequence: MAFVDEAKFFVKAGDGGNGCVSFRREKFVPKGGPNGGDGGKGGDVIMVASSKVQSLIDFRYRSHFKAERGVHGQGRDMHGRGGKDCYMDIPVGSVVKDSETGRVLADLSEEGEEFVVAQGGSGGMGNPHFSSGSNRTPRVATKGKLGEEKWLLIELKLMADVGLVGLPNAGKSTLLSKLSAANPKVADYPFTTLEPQLGMLHFPMRNSCIIADIPGLVEGAHQGVGLGHKFLRHVERTKILVHVIDASADDPFSDYDIIGNELRSYKEELADRAKILVLNKCDEFDFDKDLLPDFIEARGLEPKNVLFISAITGEGVDKLVKLIGDIIDDMEYQELKQKREEERLQDLKKQKEEERRQELKKQKEEEQAKDE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCAP_ARV
Sequence: MFCTINQKAVQPAKPSDTTTPQYPADFFNKNNHQKPTVRVTQRGYKIQELREIISNGIVQDDLNSHHVVRYMELIMEDITDTLDEDWNSFGVKIGRKGDKITPLSLVNVMIEEDELIDGKRNNGVNKKDDKWIMLVITSYYRFAFSQNQNHRSNLITKLNLQLRTFLKDPPTIVDNMGLFTSLISNINFTKLISALDMFLNRFKNNDWSYLRFGTIASRYKDCSALMSLSHVCDVTGMKMEEFMDWIFVYSTGEDMIKLMKEGNEIDNPMSYMPYTMSMGLSTKSPYSSINCPSIYSFIHMLGSFLGSERSRNARMVSENNIVNLKVNAGVVSYVKSHRASMIKAFISNDVKEQWYNNDDNDNENGGDDESDEELDEMPKGDNPVEWFMYLESRHFELPEEIKNFMNREARKITNPRVGTIGKFVSTMN
What is the function of this protein?
Encapsidates the genome, protecting it from nucleases.  If expressed without protein P it binds non-specifically RNA and therefore can bind it's own mRNA.  Interaction with protein P abolishes any non-specific RNA binding, and prevents phosphorylation.  The soluble N-P complex encapsidates specifically the genomic RNA, with protein N protecting the genome like a pearl necklace.  The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for viral transcription and replication.  Protein N binds protein P in the NC through a different interaction, and can be phosphorylated.  Subsequent viral replication is dependent on intracellular concentration of newly synthesized protein N.  During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).
What are the official names of this protein?
Nucleoprotein, NP, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the ephemerovirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.