PharMolix/UniProtQA huggingface dataset:
Protein: UBR1_MOUSE
Sequence: MADEEMDGAERMDVSPEPPLAPQRPASWWDQQVDFYTAFLHHLAQLVPEIYFAEMDPDLEKQEESVQMSILTPLEWYLFGEDPDICLEKLKHSGAFQLCGKVFKSGETTYSCRDCAIDPTCVLCMDCFQSSVHKNHRYKMHTSTGGGFCDCGDTEAWKTGPFCVDHEPGRAGTTKESLHCPLNEEVIAQARRIFPSVIKYIVEMTIWEEEKELPPELQIREKNERYYCVLFNDEHHSYDHVIYSLQRALDCELAEAQLHTTAIDKEGRRAVKAGVYATCQEAKEDIKSHSENVSQHPLHVEVLHSVVMAHQKFALRLGSWMNKIMSYSSDFRQIFCQACLVEEPGSENPCLISRLMLWDAKLYKGARKILHELIFSSFFMEMEYKKLFAMEFVKYYKQLQKEYISDDHERSISITALSVQMLTVPTLARHLIEEQNVISVITETLLEVLPEYLDRNNKFNFQGYSQDKLGRVYAVICDLKYILISKPVIWTERLRAQFLEGFRSFLKILTCMQGMEEIRRQVGQHIEVDPDWEAAIAIQMQLKNILLMFQEWCACDEDLLLVAYKECHKAVMRCSTNFMSSTKTVVQLCGHSLETKSYKVSEDLVSIHLPLSRTLAGLHVRLSRLGAISRLHEFVPFDGFQVEVLVEYPLRCLVLVAQVVAEMWRRNGLSLISQVFYYQDVKCREEMYDKDIIMLQIGASIMDPNKFLLLVLQRYELTDAFNKTISTKDQDLIKQYNTLIEEMLQVLIYIVGERYVPGVGNVTREEVIMREITHLLCIEPMPHSAIARNLPENENNETGLENVINKVATFKKPGVSGHGVYELKDESLKDFNMYFYHYSKTQHSKAEHMQKKRRKQENKDEALPPPPPPEFCPAFSKVVNLLSCDVMMYILRTIFERAVDMESNLWTEGMLQMAFHILALGLLEEKQQLQKAPEEEVAFDFYHKASRLGSSAMNAQNIQMLLEKLKGIPQLESQKDMITWILQMFDTVKRLREKSCLVVATTSGLECVKSEEITHDKEKAERKRKAEAARLHRQKIMAQMSALQKNFIETHKLMYDNTSEVTGKEDSIMEEESTSAVSEASRIALGPKRGPAVTEKEVLTCILCQEEQEVKLENNAMVLSACVQKSTALTQHRGKPVDHLGETLDPLFMDPDLAHGTYTGSCGHVMHAVCWQKYFEAVQLSSQQRIHVDLFDLESGEYLCPLCKSLCNTVIPIIPLQPQKINSENAEALAQLLTLARWIQTVLARISGYNIKHAKGEAPAVPVLFNQGMGDSTFEFHSILSFGVQSSVKYSNSIKEMVILFATTIYRIGLKVPPDELDPRVPMMTWSTCAFTIQAIENLLGDEGKPLFGALQNRQHNGLKALMQFAVAQRTTCPQVLIHKHLARLLSVILPNLQSENTPGLLSVDLFHVLVGAVLAFPSLYWDDTVDLQPSPLSSSYNHLYLFHLITMAHMLQILLTTDTDLSSGPPLAEGEEDSEEARCASAFFVEVSQHTDGLAGCGAPGWYLWLSLRNGITPYLRCAALLFHYLLGVAPPEELFANSAEGEFSALCSYLSLPTNLFLLFQEYWDTIRPLLQRWCGDPALLKSLKQKSAVVRYPRKRNSLIELPEDYSCLLNQASHFRCPRSADDERKHPVLCLFCGAILCSQNICCQEIVNGEEVGACVFHALHCGAGVCIFLKIRECRVVLVEGKARGCAYPAPYLDEYGETDPGLKRGNPLHLSRERYRKLHLVWQQHCIIEEIARSQETNQMLFGFNWQLL
What is the function of this protein?
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway.  Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.  May be involved in pancreatic homeostasis.  Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase UBR1, N-recognin-1, RING-type E3 ubiquitin transferase UBR1, Ubiquitin-protein ligase E3-alpha-1, Ubiquitin-protein ligase E3-alpha-I.
What is the protein family that this protein belongs to?
Belongs to the UBR1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: FETA_PIG
Sequence: MKWVVSIFLIVLLNFTESRTMHENAYGIASILDSSQCSAEMNLVDLATIFFAQFVQEATYKEVNQMVKDVLTVIEKSTGSEQPAGCLENQVSVFLEEICHEEEIPEKYGLSHCCSQSGEERHNCFLARKKAAPASIPPFQVPEPVTSCKAYEENRELFMTRYIYEIARRHPFLYAPTILSLAAQYDKIIPPCCKAENAVECFQTKAASITKELRESSLLNQHMCTVMRQFGARTFRAITVTKLSQKFPKANFTEIQKLVLDVAHIHEECCRGNVLECLQDAERVVSYVCSQQDTLSSKIAECCKLPTTLELGQCIIHAENDDKPEGLSPNLNRFLGERDFNQLSSREKDLSMARFTYEYSRRHPKLAVPVILRVAKGYQELLEKCSQSENPLECQDKGEEELEKYIQESQALAKRSCGLFQKLGEYYLQNAFLVAYTKKAPQLTPPELMALTRKMATTGAACCHLSEDRQLACGEGAADLIIGQLCIRHEEMPINPGVGQCCTSSYANRRPCFSSLVLDETYVPPPFSDDKFIFHKDLCQAQGVALQTMKQQFLINLVKQKPQITEEQLEAVIADFSGLLEKCCQGQEQEVCFAEEGPALISKTRASLGV
What is the function of this protein?
Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin.
What are the official names of this protein?
Alpha-fetoprotein, Alpha-1-fetoprotein, Alpha-fetoglobulin.
What is the protein family that this protein belongs to?
Belongs to the ALB/AFP/VDB family.
What are the subcellular locations of this protein?
Secreted.
Protein: CRK_RAT
Sequence: MAGNFDSEERSSWYWGRLSRQEAVALLQGQRHGVFLVRDSSTSPGDYVLSVSENSRVSHYIINSSGPRPPVPPSPAQPPPGVSPSRLRIGDQEFDSLPALLEFYKIHYLDTTTLIEPVSRSRQGSGVILRQEEAEYVRALFDFNGNDEEDLPFKKGDILRIRDKPEEQWWNAEDSEGKRGMIPVPYVEKYRPASASVSALIGGNQEGSHPQPLGGPEPGPYAQPSVNTPLPNLQNGPIYARVIQKRVPNAYDKTALALEVGELVKVTKINVSGQWEGECNGKRGHFPFTHVRLLDQQNPEEDFS
What is the function of this protein?
Regulates cell adhesion, spreading and migration.  Mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner.  Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4 (By similarity).  May regulate the EFNA5-EPHA3 signaling (By similarity).
What are the official names of this protein?
Adapter molecule crk, Proto-oncogene c-Crk, p38.
What is the protein family that this protein belongs to?
Belongs to the CRK family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=Translocated to the plasma membrane upon cell adhesion.
Protein: CINAL_GEOSL
Sequence: MKIATLSIGDELLRGEVVDTNAARIAARLADAGLAVGRHLTVGDDEGEIEAALGMLAPAHDAVIVTGGLGPTDDDVTARAAARATGRRLVLNEAALDRLRDFFSRRGRELYPANERQCLLPAKAGLIPNALGTACGFHLLHGECFLVFLPGVPAEMARMLEESVVPLVLDRRSGPEVTRTAVLTLFGLSEAEIGGRLSGLERSRGGLGIAYCVDFPVVQVKLRATARSEEEAAEIIAGGLPLVRERLGDVIVAEGDNTIDTAVARLFREKGLTLALAESCTGGLIAKRITDVAGSSAYFFMGLVTYANEAKERLLGVPTALLAEKGAVSADVARAMARGARHVAGSDLALAVTGIAGPDGGSDDKPVGTVYLALADRAGCSVKSYRFAGERDAIRTVTAVTALDWLRRRLLTA
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: CAP7_PSEAI
Sequence: MSTVATYSYTHSVTYVTDNILKSLKDIILLSGLDPEHFADRWESNTRAIKTWLGTGDLRKVILEIYNPATDKLVTRWDIDIVYGWSDGDGSFWTDTEQLKYAIKKAGLLPSQAKYKLMLDTKPGRPDVEGWSKGSYRSTDGMVKQSLGSTVEHSGLAGQAGYWRQR
What is the function of this protein?
The sensor protein for this CBASS system.  Binds to a closure peptide (consensus Glu-Val-Met-Glu-Phe-Asn-Pro), which allows it to activate CdnD for second messenger synthesis.
What are the official names of this protein?
CD-NTase-associated protein 7, Cap7, Bacterial HORMA2 sensor protein.
What is the protein family that this protein belongs to?
Belongs to the bacterial HORMA family. HORMA2 subfamily.
Protein: HDDL_ALCXX
Sequence: MTNPAYFPQLSQLDVSGEMESTYEDIRLTLRVPWVAFGCRVLATFPGYLPLAWRRSAEALITRYAEQAADELRERSLLNIGPLPNLKERLYAAGFDDGEIEKVRRVLYAFNYGNPKYLLLITALSESMQMRPVGGAEVSSELRASIPKGHPKGMDPLLPLVDATKASTEVQGLLKRVADLHYHHGPASDFQALANWPKVLQIVTDEVLAPVARTEQYDAKSRELVTRARELVRGLPGSAGVQRSELMSMLTPNELAGLTGVLFMYQRFIADITISIIHITECLDGAEAASKSPFPI
What is the function of this protein?
Dehalogenates both (S)- and (R)-2-haloalkanoic acids to the corresponding (R)- and (S)-hydroxyalkanoic acids, respectively, with inversion of configuration at C-2.  Acts on 2-haloalkanoic acids whose carbon chain lengths are five or less.
What are the official names of this protein?
2-haloacid dehalogenase, configuration-inverting, DL-2-haloacid dehalogenase, DL-DEXi.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
Protein: PSBB_DRANE
Sequence: MGLPWYRVHTVVLNDPARLLSVHIMHTALVAGWAGSMALYELAVFDPSDPVLDPMWRQGMFVIPFMTRLGITNSWGGWNITGGTITNPGLWSYEGVAGAHIVFSGLCFLAAIWHWVYWDLEIFCDERTGKPSLDLPKIFGIHLFLSGVACFGFGAFHVTGLYGPGIWVSDPYGLTGKVQTVNPTWGVEGFDPFVPGGIASHHIAAGTLGILAGLFHLSVRPPQRLYKGLRMGNIETVLSSSIAAVFFAAFVVAGTMWYGSATTPIELFGPTRYQWDQGYFQQEIYRRVSAGLAENQSVSEAWSKIPEKLAFYDYIGNNPAKGGLFRAGSMDNGDGIAVGWLGHPVFRNKEGRELFVRRMPTFFDTFPVVLVYGFGIVRADVPFRRAESKYSVEQVGVTVEFYGGELNGVSYSDPATVKKYAIRAQLGEIFELDPATLKSYGVFRSSPRGWFTFGHASFALLFFFGHIWHGSRTLFRDVFAGIDPDLDAQVEFGAFQKLGDPTTKRQAV
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP47 reaction center protein, PSII 47 kDa protein, Protein CP-47.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: YMP3_STRCH
Sequence: MPKDASGPPRSLLVLGGTSAIGLATARRLIARGARLVHLAARPSPALEKAAGELTALGAEVRTVPFDALDPESHQASLGPVFAAGDVDLVLLRFGIAGDQARDESRPLDAVRVAQTNYTGAVGAGLLCGAALQEQGHGTLVVLSSAAGVRARRADFIYGSSKAGLDAFAQGLGDALYGTGVRVMVVRPGTVLDPGTPRGDARLTTTPGQVAAAIELGLRRGSETVWVPGGLRLVMSAVRGLPRPLFRRLVV
What is the function of this protein?
May be involved in the biosynthesis of a heptaene-type antibiotic.
What are the official names of this protein?
Uncharacterized oxidoreductase in mprA 5'region, ORF3.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: AI2_USTMA
Sequence: MVRWLYSTNAKDIGTLYLIFAVFAAMIGTAFSVLIRMELAAPGVQYLNGDHQLYNVIITAHAFVMIFFMVMPAMVGGFGNYLVPVMIGAPDMAFPRLNNISFWLLPPSLILLLASAFVEQGAGTGWTVKCKLSQIIIMFVSIYNLLNITRCGKLLYSEMNTHSVLTYISTMFNDVKMSSTWGQSAWILYKIIIPRGITYIKLVVGVLSYTMYKVYTYSISLFYVVYNSVSFNKNPSETQRNVFSSGRGVNNSTNFKEWLVGITDGDGTFYFAKTKKGIWSFSFQIGQSNYNIRLLYYIKSMLGIGSVSVTHAKDNTAHYRVRNIQHIIQYILPIFDTYPLLTSKYFNYDLFKKAILIMNDSSLSNQEKDEKISYLKSQSLPDNYISPAWNNVNNQVTSILDAMSVMTKSWLIGFTEAEGSFYIVKKGPLRLVHAFEISQKLDHIVLEAIALILDIKVTTKKTYMTVVTTNYKSIENIISYFFKTMKGMKALEYRIWARSFNKKGSGRFEYMTKIQNLMRNIRSIRLDKNFTKK
What is the function of this protein?
Mitochondrial DNA endonuclease involved in intron homing.
What are the official names of this protein?
Probable intron-encoded endonuclease aI2.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion. Membrane; Multi-pass membrane protein.
Protein: CYSH_VIBVU
Sequence: MLDSVASTLQLSELLSLTKAEQSIRLAEINVELEMLSAQERVAWALQNLEGAHAVSSSFGIQAAVMLHLVSKQQADIPVILTDTGYLFPETYQFIDELTKSLNLNLKVYRANESANWQEARYGKLWEQGIEGIEKYNKLNKVEPMRRALNELNVKTWFSGLRREQSQSRAGLPILSIQNGVFKFLPVVDWSNKDVHYYLKEHGLSYHPLWEQGYLSVGDTHTTQKWEPGMSEEETRFFGLKRECGLHEEDNEQDGSGI
What is the function of this protein?
Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
What are the official names of this protein?
Phosphoadenosine 5'-phosphosulfate reductase, PAPS reductase, 3'-phosphoadenylylsulfate reductase, PAPS reductase, thioredoxin dependent, PAPS sulfotransferase, PAdoPS reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCTA_DECAR
Sequence: MAKKAVFKSLYFQVLVAIAIGVSLGHFYPETGAAMKPLGDGFIKLIKMIIAPIIFCTIVVGIAGMEDMKKVGKTGGLAVLYFEVVSTIALVIGLIVVNVWAPGVGMNVDVSTLDTKGIAKYAQPGQMQTTTDFLMNIIPTSVVDAFAKGDMLQVLFFSILFGYAMHSFGERGKPVFELIEKLSHVLFGIVGVIMKVAPIGAFGAMAYTIGKHGVGSLAQLASLMGAFYLTCVIFILGVLGSIAAFHGFSIIKLIKYIKEELFLVLGTSSSESALPRLMAKMENAGAQKSVVGLVVPTGYSFNLDGTSIYLTMAAVFIAQATNTPLDLQHQVTLLVILLLTSKGAAGVTGSGFIVLAATLSAVGTVPVAGLALILGIDRFMSEARALTNFIGNSVATLVVAKWCNALDAKRMNAVLNNETSDEAENPELVLDDAPDVIIPHVPRPIIDHH
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPD_STRPZ
Sequence: MTKKEQALIEQYAKSLVEVASEHHSLDALQADVLAILETFVTTNLDQSLSSLAVPHAEKIKLLTLLKGNNSVYMNNFLNLILQNEREAYLYQMLQAVLNEIAIVSNQYDVTVTSSLPLTEEQKSRVRAVVAKKFAVTAGRLIEKVDPSLIGGFIISVNNKVIDTSIRRQLQAFKMNLK
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RIMP_METNO
Sequence: MTDAPDHHPADAAEKRLITETGVAARVAQIVEPSLEGLGFRLVRVRVTGQNGCTVQIMAERPDGTMTVEDCESVSRTISPLLDVDDPIGRAYHLEISSPGIDRPLVRVGDFARWAGHEAKVELTVPLEGRKRFRGIIRAPEGESVRIDLPDAKEGTPASYDLRLRDIGEAHLVLTDALIRESLRRGSAPVEDEEGEGEAPTAH
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIF3M_ANOGA
Sequence: MQGPAVFIDAEIDDQAQELRQFLKGLGAEISEEKSTKGIEDDLHKIIGVCDVCFKDNTHSPEEIDAVLNSIVSIIVSIPLERGENLILSFCDKMTKAKETSLARVCLQSLWRLFSNLEVTSPLRYHVYYHLVQVAKQVNQVKEVFTGVEQLKAQFAQCPPSNEQMQKLYRLLHDVLKDSNSELASKVMIELLGTYTAENASYAREDAMKCIVTALADPNTFLLDPLLSLKPVRFLEGELIHDLLSVFVSEKLPSYLEFYKNHKEFVNSQGLNHEQNIKKMRLLSFMQLAESNSEMTFQQLQDELQIKEEEVEPFIIEVLKTKLVRARMDQRARKVHISSTMHRTFGRPQWQQLRDLLLSWKSNLTLVQENINTVSAAQMELAQRQ
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit M, eIF3m.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit M family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPR_VIBC1
Sequence: MSHEPEYKDWQQIVELIRSSVDNQQHEMLLTMLMTPDERESLTARVNILNELLKGELSQRQISQMLGVGIATITRGSNELKSKSDTDKDKLKTLLEQGAQ
What is the function of this protein?
This protein is an aporepressor.  When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription.
What are the official names of this protein?
Trp operon repressor homolog.
What is the protein family that this protein belongs to?
Belongs to the TrpR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFSA_HAEI8
Sequence: MQLPALQSAKLIRRYKRFLADIELPTGDVMTIHCANTGAMTGCGEKGDTIWYSHSDSQTRKYPHSWELTQLANGQLCCINTHRSNQLVFEALQNKQIKELAMYDEIYPEVKYGEENSRIDFLLKGEGLPDCYVEVKSITLVKGNLGMFPDAVTTRGQKHVRELLAMKKQGHRAVVLFAGLHNGFDRFKIAEYIDPEYDRLLKEAMEQGVEAYAYAGQFEISNEIPTALSLTESVPYIK
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: CH10_SHESA
Sequence: MNIRPLHDRVIVKRLEVESTSAGGIVLTGSAAEKSTRGEVLAVGNGRILENGTVRPLDVKVGDVVIFNEGYGVKKEKIDGQEVLILSEADLMAIVG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UP01_CYCRE
Sequence: TDVLGLPAK
What are the official names of this protein?
Unknown protein 1.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: APR1_CAEBR
Sequence: MSSSSSDENETTIHSSSNPGSSGIYSQLKAGSSKRPSVRHDVSDAEDDEEPYEGFRKDMNMEVDERITTLLSSLHFEHKRDVVTADEDDNKLRELHENIFSLITTEPDFHRRRRLKKALPASNCIREQVYYLRRKPITPPDSYYHRLNAALHTIVKESFGEEYRKVATVLGLVEALAEVLILEVHAFGIPETNAVEHRNIRKLIANALTNLTYGQILSKRRLCSYDGFIRCVVRIIIESPNITQVYAGLIRNLSWNADSGMSEALQPTVHALSLAAVYAHTHRFDVTAILSALWNLAGHSVENKRTICETPNCLKVLANILSPDARFTTLVDSASGILKYVSQYLATNSSHLELRSLLITRMLTLLKSSSFTCVTNTLGAIAHLIAKDPHMQQLIRQDAAAVQQLNVLRNSNREDIRKAVKEVLNTLNQPCSHRYGDMSHSVGGASGMLSEPQLQMQTSHHGYHGTASPRLLSLRATRASPGKYIHPSQQQHMQVPAPDQRSSSLPRHFAVQRNGFMMAQSFNQQMDPHQQQQQQQQQMIFQMQQQQMMIQTDDQQMRYLNQQQQQQQQQHYQQQIQRNQNVEPVLPVDDDLDIPTSTVMGTRSNSERSLGSMNPGSVMTTGGWNSTLDTAANSSRALSPVSFSDIPASPTMCAQVFNLPVHPEDNQMTTPPNHPSTQNTTHYSSGSANTMTRSDGTTVPIDNLITPTYATLNVTNNAARKTSEDLESPDDILPGPSLEVEEEGDYAIITGAEQKSDDDLLTRSIQEEMPTSSSTPKLKVSPRLNGFFSPSQKTTSSPAWSHPDTSPILKQTQRPKHHEMTTDSDRLLMESIMSEMPRSRVISPRLASGGQQYLDPEPDRSSHSKNEEADRRDAIIASHEPSDQGMNVGRGSSPQQQQLHRMESLESQASSEDSFGLNGYQEEHNTSSSAAHTMRIDKDDVVDASLPMDCVDDEDYDYTDDHFDDNYEEDYEDSNATQFDEGIDPQLTIDCSMISSGSGSSLQKAETTAGSRDSGALATSTPIGSVSSLPGVRRAKKVSINGKTRLPVPKTNGSLVDRVRKPVIEASRPRLPPKPSLLKGKQYHEEDLIENQTRDDTIYVNAPIVEAEQERIYMNALKHSQGSPSVNGTPPKSAIVSPYNYQKPPFTERSNGEINEKNVTPNPKQMLVTIV
What is the function of this protein?
Has a role in endoderm cell specification and pharyngeal development.  Required for the migration of epithelial cells, organization of the anterior seam cells and ceh-13 expression during embryo morphogenesis.  Prevents hyperactivation of the Wnt signaling pathway during endoderm development, probably by preventing hmp-2 nuclear translocation.  During larval development, apr-1 is required for expression of lin-39 in P3-8. p.  Shown to negatively regulate Wnt signaling in vulval precursor cells.  Has a role in cell division by establishing the polarity of the mother cell which forms the asymmetries of the daughter nuclei.  Thought to regulate export of wrm-1 from the nucleus possibly as part of a complex involving pry-1.
What are the official names of this protein?
APC-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the adenomatous polyposis coli (APC) family.
What are the subcellular locations of this protein?
Cell junction, adherens junction. Cytoplasm. Nucleus. Note=Found in clusters near the ends of microtubules that extend into regions of actively migrating plasma membranes. Shuttles between the cytoplasm and nucleus (By similarity).
Protein: ATPL_BUCAP
Sequence: MESLNVDMLYIAVAIMIGLAAIGAAIGIGILGSKFLEGAARQPDLVPLLRTQFFVVMGLVDAIPMIAVGLGLYMLFAIS
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CHS2_RUTGR
Sequence: MAAVTVEEIRKAQRADGPAAVLAIGTATPANYVTQADYPDYYFRITKSEHMTELKEKFKRMCDKSMIRKRYMYLTEDILKENPNMCAYMAPSLDARQDIVVVEVPKLGKEAAVKAIKEWGQPKSKITHLIFCTTSGVDMPGCDYQLTKLLGLRPSVKRFMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPADTHLDSLVGQALFGDGAAAVIVGADPNESIERPLYQLVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLKEAFGPIGISDWNSIFWIAHPGGPAILDQVEAKLGLKEEKLRATRQVLSEYGNMSSACVLFILDEMRKKCAEEGRATTGEGLDWGVLFGFGPGLTVETVVLRSVPINA
What is the function of this protein?
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
What are the official names of this protein?
Chalcone synthase 2, Naringenin-chalcone synthase 2.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: Y2558_ORYSJ
Sequence: MAASLPLSAAIVGAEESVDKEVLEMEYLFEKFLMPSDLCSNTEWLGIPEEHVRKFGMMLEDRDGYSVIFFQDGVVPGKLWCFRYWKSNGVHGLTKGWRCFVREKGLKAGDTISFFRGSACGRLFICCRLGTHATFASSSTLHHGFSMPPPPARPLVGLQSGMLARDVPSLGQARLHDGNQDGGGAPSRHVPSSGRRVEAQLSRVSSRRQRRTMKHSIPEPTIETPPILESMFLIAAPPAVKCLRLFGVNIYVLPVSSSGQPKQESSP
What are the official names of this protein?
B3 domain-containing protein Os02g0455800.
What are the subcellular locations of this protein?
Nucleus.
Protein: MDH_METKA
Sequence: MSKVAVIGATGRVGSTAAARLALLDCVNEVTLIARPKSVDKLRGLRRDILDSLAAAQKDAEITIGCERDDYVDADVIVMTAGIPRKPGQTRLDLTKDNAAIIKKYLEGVAEENPEAIVLVVTNPVDVLTYVALKVSGLPKNRVIGLGTHLDSMRFKVLIAKHFNVHMSEVHTRIIGEHGDTMVPVISSTSVGGIPVTRMPGWEDFDVEEAVREVKEAGQRIIETWGGSQFGPAQAITNLVRTILQDERRVLTVSAYLDGEIDGIRDVCIGVPARLGREGVLEIVPIELEEDEMRAFRRSVKVVKEATREAMEAISER
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily.
Protein: APT_BACVZ
Sequence: MDLKKYVTIVPDYPKEGVQFKDITTLMDKGDVYRYATDQIVEYAKEKEIDLVVGPEARGFIIGCPVAYALGVGFAPVRKEGKLPREVIKVDYGLEYGKDVLTIHKDAILPGQRVLITDDLLATGGTIEATIKLVEELGGVVAGIAFLIELSYLDGRDKLDDYDILTLMKY
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYRIB_BOVIN
Sequence: MGNLLKVLTCTDLEQGPNFFLDFENAQPTESEKEIYNQVNVVLKDAEGILEDLQSYRGAGHEIREAIQHPADEKLQEKAWGAVVPLVGKLKKFYEFSQRLEAALRGLLGALTSTPYSPTQHLEREQALAKQFAEILHFTLRFDELKMTNPAIQNDFSYYRRTLSRMRINNVPAEGENEVNNELANRMSLFYAEATPMLKTLSDATTKFVSENKNLPIENTTDCLSTMASVCRVMLETPEYRSRFTNEETVSFCLRVMVGVIILYDHVHPVGAFAKTSKIDMKGCIKVLKDQPPNSVEGLLNALRYTTKHLNDETTSKQIKSMLQ
What is the function of this protein?
Negatively regulates RAC1 signaling and RAC1-driven cytoskeletal remodeling.  Regulates chemotaxis, cell migration and epithelial polarization by controlling the polarity, plasticity, duration and extent of protrusions.  Limits Rac1 mediated activation of the Scar/WAVE complex, focuses protrusion signals and regulates pseudopod complexity by inhibiting Scar/WAVE-induced actin polymerization.  Protects against Salmonella bacterial infection.  Attenuates processes such as macropinocytosis, phagocytosis and cell migration and restrict sopE-mediated bacterial entry (By similarity).  Restricts also infection mediated by Mycobacterium tuberculosis and Listeria monocytogenes (By similarity).  Involved in the regulation of mitochondrial dynamics and oxidative stress (By similarity).
What are the official names of this protein?
CYFIP-related Rac1 interactor B, Protein FAM49B.
What is the protein family that this protein belongs to?
Belongs to the CYRI family.
What are the subcellular locations of this protein?
Membrane; Lipid- anchor. Mitochondrion.
Protein: 6PGD9_ECOLX
Sequence: MSKQQIGVVGMAVMGRNLALNIESRGYTVSVFNRSREKTEEVIAENPGKKLVPYYTVQEFVESLETPRRILLMVKAGSGTDSAIDSLKPYLDKGDIIIDGGNTFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILKQIAAVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYALLKGGLTLSNEELAQTFTEWNEGELSSYLYDITKDIFTKKDEEGKYLVDVILDEAANKGTGKWTSQSSLDLGEPLSLITESVFPRYISSLKDQRVAASKVLSGPQAQPAGDKAEFIEKVRRALYLGKIVSYAQGFSQLRAASDEYNWELNYAEIAKIFRAGCIIRAQFLQKITDAYAQNAGIANLLLAPYFKQIADDYQQALRDVVAYAVQNGIRVPTFSAAIAYYDSYRSAVLPANLIQAQRDYFGAHTYKRTDKEGVFHTEWLE
What is the function of this protein?
Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
What are the official names of this protein?
6-phosphogluconate dehydrogenase, decarboxylating.
What is the protein family that this protein belongs to?
Belongs to the 6-phosphogluconate dehydrogenase family.