PharMolix/UniProtQA huggingface dataset:
Protein: EX7L_TROWT
Sequence: MDMQADEMYRQDPLGSCGNPRQVSHITGRLSSLLGELPATWIEGEVTQLSPRRIGVFLTLKDMNESKHLEFFLPFDAFKDEVEVGNRVKIHGKLEFWATSGQIKVKGFEIQSVGIGELIERIARLRVQLALEGLYEHKRPLPFIPKLIGLVTGQNSDAEKDVVTNVLLRWPAAKFCTIYASMQGASCVSETISAIQKLDANNDVDVIIVARGGGSFHDLIGFSDEQMIRAVFAIKTPLISAIGHEADRPILDEVADLRASTPTDAAKRVVPDIADEKRLIKSAMSFLKKSYEPVIDKIKCDTLSWSQAFSNPFETFIAPRRREIDLFYQQMLTVVWANFSKTETEIAAIKKHLLAISPQNTLVRGYAMIEDETGRIISSADKLSAGDTVTLRLHDGLVRAEITQ
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSPA_MYCBO
Sequence: MPDEPTGSADPLTSTEEAGGAGEPNAPAPPRRLRMLLSVAVVVLTLDIVTKVVAVQLLPPGQPVSIIGDTVTWTLVRNSGAAFSMATGYTWVLTLIATGVVVGIFWMGRRLVSPWWALGLGMILGGAMGNLVDRFFRAPGPLRGHVVDFLSVGWWPVFNVADPSVVGGAILLVILSIFGFDFDTVGRRHADGDTVGRRKADG
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PDXH_ALISL
Sequence: MELEDIRRDYSLGGLRRADLPQAPIELFELWLKQAVEAKLTDPTAMTVATVDKKGQPFQRIVLLKHFDSTGFVFYTNLASRKAQHLEDNSKISLHFPWHPLERQVHITGTAEKLTALENMKYFTSRPKESQIAAWASKQSSRLTARAALEGKYLELKQQFSKGEIPVPKFWGGFRVKIDSIEFWQGGDSRLHDRFLYSKDQDKWVIDRLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: PQQD_PSEAE
Sequence: MSLPSLDSVPMLRRGFRFQFEPAQDCHVLLYPEGMVKLNDSAGEILKLVDGRRDVAAIVAALRERFPEVPGIDEDILAFLEVAHAQFWIELQ
What is the function of this protein?
Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
What are the official names of this protein?
PqqA binding protein, Coenzyme PQQ synthesis protein D, Pyrroloquinoline quinone biosynthesis protein D.
What is the protein family that this protein belongs to?
Belongs to the PqqD family.
Protein: MFR6_PHOSM
Sequence: MVSARGILYYLSHPQELRPMIQWKVFHGLAHQRDEKNESPDVQACYYYLALTSRSFVAVCQQLDPELLMPICIFYLVLRGLDTIEDDMTLSTEVKEPLLRNFHTTIYDQSWTFHDSGPDEKDRELLVHFDCVAREFAKVKDEYKVIITDITKKMGNGMADFVVNGELTGVRKIEDYELYCHYVAGVVGEGLTRLFVEAKVAEPSLLENPKLIESMGQFLQQTNIIRDVREDHDEVRHFWPKEVWAKYADDFDQLVSPIPQNRQKALQCSSEMVLMALNRADDCLNYISGVREQSVFNFVAIPQSMAIATLELCFQNPAIFDKNIKITKGTACQLMMDSTQDMQHVCQAFRRHARRIQKKNNPKDPHFHDINAACNKIERFIDGRYPNLQDEQAKADTMYLVVLLLGILGVAAAVLMAKR
What is the function of this protein?
Squalene synthase; part of the gene cluster that mediates the biosynthesis of squalestatin S1 (SQS1, also known as zaragozic acid A), a heavily oxidized fungal polyketide that offers potent cholesterol lowering activity by targeting squalene synthase (SS) (PubMed:27056201).  Catalyzes the condensation of 2 two farnesyl pyrophosphate moieties to form squalene (By similarity).  The presence of a gene encoding a squalene synthase supports the identification of the cluster as being responsible for SQS1 production and suggests a likely mechanism for self-resistance (Probable).
What are the official names of this protein?
Squalene synthase R6, SQS, SS, Squalestatin S1 biosynthesis cluster protein R6.
What is the protein family that this protein belongs to?
Belongs to the phytoene/squalene synthase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL10_ANAD2
Sequence: MNRTEKEQVISELHEKMAKAKAAIVAEPKGLNVAVVTDLRKKLRDAKIDYRIVKNTLAARAAKGTPVEPVADRFVGPTALVMSYDDVVTPAKLLADFMKDRENFVIRTAIIEGKVIDAKGVQALAKMPGLKELRGQIAAMIAQPATKLARLVGTPGQQLARVVGARREQLEKQA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: KTHY_SALPA
Sequence: MGSNYIVIEGLEGAGKTTARDVVVETLEQLGIRNMIFTREPGGTQLAEKLRSLVLDIRSVGDEVITDKAEVLMFYAARVQLVETVIKPALAQGIWVIGDRHDLSTQAYQGGGRGIDQTMLATLRDAVLGDFRPDLTLYLDVTPEVGLKRARARGDLDRIEQESFDFFNRTRARYLELAAQDSRIRTIDATQPLDAVMRDIRATVTKWVQEQAA
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: SPCS_METMP
Sequence: MLDFNIEGLIPKNMEKRGELVLNEYLKEIEDVFNHRKIPENGIDDEKIKLFLKFLSMMDTDKDPKSVRIGEREARTYSKIHEELSSGFCHGIGRSGNLVDPQPKASGASIMYALTNKILESFFKQLGLNVHAIATPISTGMSISLCLSAARKKYGSNVVIYPYASHKSPIKAVSFVGMNMRLVETVLDGDRVYVPVEDIENAIKKEIELGNRPCVLSTLTFFPPRNSDDIVEIAKICENYDIPHIINGAYAIQNNYYLEKLKKAFKYRVDAVVSSSDKNLLTPIGGGLVYSTDAEFIKEISLSYPGRASATPVVNTLVSLLSMGSKNYLELVKNQKNSKKLLDELLNDLSKKTGGKFLDVESPIASCISVNSDPVEIAAKLYNLRVTGPRGIKKTDHFGNCYLGTYTHDYIVMNAAIGVRTEDIVNSVSKLEKILL
What is the function of this protein?
Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
O-phosphoseryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase, Sep-tRNA:Sec-tRNA synthase, SepSecS.
What is the protein family that this protein belongs to?
Belongs to the SepSecS family.
Protein: ACT_ACHBI
Sequence: MADDDVQALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPKHPGIMVGMDQKDAYVGDEAQSKRGVLTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANRERMTQIMFETFNVPAMYVNIQAVLSLYASGRTTGCVLDSGDGVSHTVPIYEGYALPHAIVRLDLAGRDLTDYMMKILTERGYSFTTTAEREIVRDIKEKLTYIALDFDQEMKTAAESSGLEKSYELPDGNVLVIGNERFRTPEVLFQPALIGKEASGIHDCTFQTIMKCDVDIRKDLYCNIVLSGGTTMYPGISERMTKELTALAPSTMKIKVVAPPERKYSVWIGGSILSSLSTFQQMWISKAEYDESGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RNC_HELP2
Sequence: MKNKRSQNSPYVTPNNPYLTLEKALGYSFKDKRLLEQALTHKSCKLALNNERLEFLGDAVLGLVIGELLYHKFYQYDEGKLSKLRASIVSAHGFTKLAKAIALQDYLRVSSSEEISNGREKPSILSSAFEALMAGVYLEAGLAKVRKIIQNLLNRAYKRLDLEHLFMDYKTALQELTQAQFCVIPTYQLLQEKGPDHHKEFEMALYIQDKMYATAKGKSKKEAEQQCAYQALQKLKEAK
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_SHEB2
Sequence: MAKVPSRSPRKRVRKQVADGMAHIHASFNNTIVTITDRQGNALSWATSGGSGFRGSRKSTPFAAQVAAERAGAAAQDYGLKNLEVFVKGPGPGRESAIRALNAVGYKITNITDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: IF2_ACIBS
Sequence: MTDKSIKELALSVGRPVEKLLEQAREAGLPQRTADDIITTEQQDTLVNYLKKVHGQESGNTGKIALKRKTTSTAKVASTSGKAKTINVEVRKKQVFAKPNPEQIAAEAKARAEAEAKARAEQQAREAAEQKARLQTEQKAKATLDAMRAAHQQDSAAQSAPKAAVVVEKRGGGTVKPAPKPAETLEQKKAREAQTAQLKATEEAARRKAAEEAQQRTLEQMRKMASKYSNDDATATIRVIDDSPLASGLVGQAYEDSFNQEDREIKRGGATTNPRAGKKGGRRGQEEQSFVNHNKRGLKSSQANKHGFEKPVKKQVYDVEIGSSIVVADLAQKMAIKVREVIKTLMKMGELVNQNQTIDQDTAALVVEEMGHNPVLVSDTQAEDNLLEAAEEARGEQTTRPPVVTIMGHVDHGKTSLLDRIRRSKVAAGEAGGITQHIGAYHVETDKGIITFLDTPGHAAFTSMRARGAKATDIVVLVVAADDGVMPQTAEAIDHARAAGTPIIVAINKMDKESADPDRVLNELTTKEIVPEEWGGDVPVAKVSAHTGQGIDELLDLILIQSELMELKASAEGAAQGVVIEARVDKGRGAVTSILVQNGTLNIGDLVLAGSSYGRVRAMSDENGKPIKSAGPSIPVEILGLPEAPMAGDEVLVVNDEKKAREVADARADREREKRIERQSAMRLENIMASMGKKDVPTVNVVLRTDVRGTLEALNAALHELSTDEVKVRVISSGVGAITESDVILAESSEAVLLGFNVRADTAARQKSDQDGIDIRYYSIIYELIDDVKDAMSGKLAPEHRETILGVAQVREVFRSSKFGAAAGCMVMEGVIHRNKPIRVLRDDVVIFQGELESLRRYKDVVDEVRAGMECGLAVKGYNDIKPLDKIEVYDVQIVKRSL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPP2_BURP0
Sequence: MDWILICKALALGIVEGLTEFLPVSSTGHLIVAGSFLRFHPEQAKTFDVVIQFGAILAVCWEYRRRIIDVVTGLPAQREARRFTMNVVIATVPAVALALLFEKTIKSVLFAPVPVAVALVVGGAAILWVEGRQRERSEPARVQSIDALTPFDALKVGLAQCCALIPGMSRSGSTIIGGMLFGLERRVATEFSFFLAIPVIFGATLYETAKDWRAFNVDSVGLFAIGLVAAFVSAFACVRWLLRYVASHDFTAFAWYRIAFGLFVLLVGYSGWIEWT
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase 2, Bacitracin resistance protein 2, Undecaprenyl pyrophosphate phosphatase 2.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KGUA_STRPN
Sequence: MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQRPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLEIEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALMREYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPA_RUBXD
Sequence: MRHRWEDRPVAPPPDGRPTEYLPFRQERGRHGRPGWLKARVPDGPGYREIKETMRGLSLHTVCEEARCPNIGECWNNRTATFMILGNVCTRSCGFCAVLTGRPQELDLEEPYRVADAVKKMGLRHAVITSVNRDELPDGGASVFAATIRAIRREVPGCAVEVLTPDFKGDRDAIKTVIDARPDTFNHNIETVPRLYPAVRPQAKYGRSLEVLRYAKELDPGVLTKSGFMVGLGEVEEEIVRTMRDLREHGVDILTIGQYLRPTENHLPMARYYTPQEFARYKKLGLEMGFSHVESGPLVRSSYHAHEQTEDARRGALGARG
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMA_I64A5
Sequence: MNTQILILATSAFLCVRADKICLGHHAESNGTKVDTLTEKGIEVVNATETVEQKNIPKICSKGKQTIDLGQCGLLGTIIGPPQCDQFLEFSANLIIERREGNDICYPGKFDDEETLRQILRKSGGIKKENMGFTYTGVRTNGETSACRRSRSSFYAEMKWLLSNTDNEVFPQMTKSYKNTKREPALIIWGIHHSGSTAEQTRLYGSGNKLITVWSSKYQQSFAPNPGPRPQINGQSGRIDFYWLMLDPNDTVNFSFNGAFIAPDRASFLRGKSLGIQSDAQLDNNCEGECYHIGGTIISNLPFQNINSRAIGKCPRYVKQKSLMLATGMKNVPENSTHKQLTHHMRKKRGLFGAIAGFIENGWEGLIDGWYGYRHQNAQGEGTAADYKSTQSAINQITGKLNRLIEKTNQQFELIDNEFNEIEKQIGNVINWTRDSIIEIWSYNAEFLVAVENQHTIDLTDSEMNKLYEKVRRQLRENAEEDGNGCFEIFHQCDNDCMASIRNNTYDHKKYRKEAIQNRIQIDAVKLSSGYKDVILWFSFGASCFLFLAIAMGLAFICIKNGNMRCTICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: TCTP_WUCBA
Sequence: MLIFKDAFTDDELASDSFPMKLVDGLIWEFKGRQVVRREGEIQLAGANPSTEGEDGDEGSEECVERGIDFVLNHRLQEMNCYEDLATFKSYCKSFMKKVVELMQKNGKSEAEISEFKRKIQAWVVSLLSKDRFKQLQFFIGERMAEGQGEGQVAVVEYRDEEEGEVPYLMLVKEALVEEKQ
What is the function of this protein?
Involved in calcium binding and microtubule stabilization.
What are the official names of this protein?
Translationally-controlled tumor protein homolog, TCTP.
What is the protein family that this protein belongs to?
Belongs to the TCTP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CY4C_PSEPU
Sequence: MTFPFSGAAVKRMLVTGVVLPFGLLVAAGQAQADSQWGSGKNLYDKVCGHCHKPEVGVGPVLEGRGLPEAYIKDIVRNGFRAMPAFPASYVDDESLTQVAEYLSSLPAPAAQP
What is the function of this protein?
This is the heme-containing component of the p-cresol methylhydroxylase.  It accepts electrons from the flavoprotein subunit.
What are the official names of this protein?
4-cresol dehydrogenase [hydroxylating] cytochrome c subunit, Flavocytochrome c, P-cresol methylhydroxylase cytochrome subunit.
Protein: LGT_PROM2
Sequence: MLILQAFIQSPGETFLNLGFITIRWYGLLISVSVLIGLFVSKKLAKARNINPEYISEILPSLIISSILGARAYYVIFEWRQYSGENFFTSFELFNSIIKIPSFFAVWEGGIAIHGGLIGGLISIIYFCKSKNINLKTFIDILIPSIILGQSIGRWGNFFNNEAFGVPTNLPWKLFIPIQNRPLEFLNYEFFHPTFLYESLWNLLIFIALIIIFNKQNKTDFFRPGFISFLYLISYSFGRFWIEGLRTDPLCIGGLPPFCDGGIRMAQFISIFLFSSGLIGIFFLRLRSCNGKNRKNG
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CH60_SHESW
Sequence: MAAKEVVFGNDARVKMLAGVNILANAVKVTLGPKGRNVVLDKSFGSPLITKDGVSVAKEIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIVTEGLKAVAAGMNPMDLKRGIDKAVIAAVAELKALSQPCADSKAIAQVATISANSDESIGEIIATAMEKVGKEGVITVEEGQALENELDVVEGMQFDRGYLSPYFINKPETGSVELDHPFVLLVDKKISNIRELLPILEGLAKTGKPLLIVAEDVEGEALATLVVNNMRGIVKVAAVKAPGFGDRRKAMLQDVAILTGGTVIAEEIGLELEKATLEDLGTAKRVVITKDNTTIIDGNGEQAQIEARVSQIKQQIEESTSDYDKEKLQERMAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVPGGGVALVRVASKIAELEVLNEDQKHGVVIALRAMEAPLRQIATNAGEEASVVANTVKNGSGNYGYNAGNDTYGDMLEMGILDPTKVTRCALQFAASIAGLMITTEAMVAEIPQNSAPDMGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADE_CHLL3
Sequence: MTTVPCFIAGLPKAELHLHIEGTLEPAMMLRLAERNRQPPPFPDVETAEKAYRFTNLQSFLDIYYRSTEVLVTEEDFYDLTLAYLEKAASQKIGHAEIFFDPQAHTVRGIAFATVLRGMEEACREAHSRLGISTRLIMCILRHLSEQEGMTMLNEAVRWKRWITGIGLDSSERGNPPSKFHNLYREARREGFFLTAHAGEEGSAASVKETLDLLHVDRIDHGVRCMDDPALVKELVRRAVPLTVCPLSNVKLQVFGSMQEHNLKAMLEKGLMVTLNSDDPAYFGGYLNDNFTAAAEALDLSFSDIIRLAANSFNASMLSIVQKKIHLLELADYARGFAPGH
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenine to hypoxanthine.  Plays an important role in the purine salvage pathway and in nitrogen catabolism.
What are the official names of this protein?
Adenine deaminase, ADE, Adenine aminohydrolase, AAH.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
Protein: LPXD_NEIMB
Sequence: MIPATYTLSQITARLGGEWRGEDISVTAVRPLADAQAEHISFLANPKYKAEVHDSSAGAVIVSAKAADGFEGRNLIVADDPYLYFAKVARLFSPVVKARGGIHPTAVVEPGATVPTSCEIGANVYIGANTVLGEGCRILANAVVQHDCKLGDEVVLHPNAVVYYGCTLGRRVEIHSGAVIGADGFGLAFADDSWFKIPQTGAVTLGDDVEIGSNTNIDRGAMSDTTVGNGTKIDNQVQIGHNCKIGSHTVIAAKTGISGSVTIGSYCIIGGGVGTVGHIEIADKTTIGGGTSVTHSITESGKHLAGIFPMSTHKEWARNAVYIHRLSEMNKRLKTLEQQLSDAGQDSK
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: OBG_PHOLL
Sequence: MKFVDEARILVVAGDGGNGCVSFRREKYIPKGGPDGGDGGDGGDVYLLADENLNTLIDYRFEKSFRAERGQNGQSRDCTGRRGQDTTIKVPVGTRVRDAVTGEVLGDMIRHEQRLMVAKGGFHGLGNTRFKSSVNRAPRQRTMGTSGETRELMLELMLLADVGMLGMPNAGKSTFIRAVSAAKPKVADYPFTTLVPSLGVVRMDNEQSFVVADIPGLIKGASDGAGLGIRFLKHLERCRVLLHLIDICPVDGSDPVENARIIVNELQQYSEKLAEKPRRLVFNKVDLLEPEEARQRAQAIADELGWEGDFYMISAINRQGVKALCWDIMEFMKTQPRNMSRTEGETQPEKVEFMWDDYHKKQLEQVSEVDDDWDDDWDEDDDEGIEVIYKR
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UFSP_CAEEL
Sequence: MTNSQTVSLIGPTQMAPQSTPPPPVNELWFIDAQAMFQNYANLRSFSKSNANEINTTIGGFVFGRKARKQVIHVLFAYAEDLTESNRQFLESSLSADIELVGNLNIDGQSQILPGGQFTLQLTSRMLENRSISEFLDMNVMFNNEHVLMEGASCVSRVGYEWSLRAGREQEDVKSAAERLSMASFRFTYLNAEHGLVIREQKPEAAQQKYLDKFSKGAVPYKDVIEFTAMQSLTRDTSNDTEDQKLVPTVKVTKDNKHFTRLVTIGEVVFPAFFGDSSLDLYKRSREAFNRRANNTMMVTVNGIRAGRGVTTTTSATYLPPGWVSLLHLQLPTKWTDNEQRNYRIRLHKLFNLPSSKPVLRLSQALALHSESARLTNKKLIREPHLSITNYQPVGEITTVNGPYNYHHYMQDGIDDSGWGCAYRSFQTIWSWFILNGYTDKPVPSHREIQQALVDIQDKQAKFVGSRQWIGSTEISFVLNELLKLECRFIATNSGAEVVERVRELARHFETSGTPVMIGGNMLAHTILGVDFNDTTGETKFLVLDPHYTGSEDIKTITSKGWCAWKPASFWSKDHFYNMVLPQPPSDAI
What is the function of this protein?
Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ufm-1, a ubiquitin-like modifier protein bound to a number of target proteins (PubMed:29251776, PubMed:24603482).  Required, with oct-4, for the localization of a subset of 7 transmembrane domain odorant receptors, including odr-10, to the cilia of olfactory neurons AWA and AWC (PubMed:9590179).  Operates in aggregation behavior, and responses to oxygen levels (PubMed:12410303).
What are the official names of this protein?
Ufm1-specific protease, UfSP, Odorant response abnormal protein 8.
What is the protein family that this protein belongs to?
Belongs to the peptidase C78 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Cytoplasm. Cytoplasm, perinuclear region. Note=Recruited to the endoplasmic reticulum upon interaction with odr-4.
Protein: ASSY_PSYA2
Sequence: MAQLDPKTINKIVLAYSGGLDTSIIARWLQETYDAEVITFTADIGQGEEVEPARAKAEAMGIKHIHIEDLREEFARDYVFPMFRANAIYEGEYLLGTSIARPLIAKRLVEIAKEHNADAISHGATGKGNDQVRFELGAVALSPDVVTIAPWREWDLSSRESLMEYAKEHNISIDYAGNKKKSPYSMDANLLHISYEGGILEDPYAEAEDDMWRWSVSPEQAPDVPQYLELEYAKGDIVAIDGEALKPYEVMIKLNEIGGKHGIGRLDIVENRYVGMKSRGCYETPAGTIMLKAHRGIESLTLDREAAHLKDELMPRYAKTIYNGYWFSPERMMLQALIDKSQEYVNGTVRVKLYKGAVSVVGRKSDDSLFDEKIATFEDDAGAYDQKDAEGFIRLNGLRLAIEASRGRDLSK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSTT_SALAR
Sequence: MATQRASGLLQRLAQGSLVKQILVGLVLGILLAWVSKPAAEAVGLLGTLFVGALKAVAPILVLMLVMASIANHQHGQKTNIRPILFLYLLGTFSAALAAVVFSFAFPSTLHLSSSAQDIVPPSGIVEVLRGLLISMVSNPIDALLNANYIGILVWAVGLGFALRHGNETTKNLVNDMSNAVTFMVKLVIRFAPVGIFGLVSSTLATTGFSTLWGYAHLLVVLIGCMLLVALVVNPLLVFWKIRRNPYPLVFACLRESGVYAFFTRSSAANIPVNMALCEKLNLDRDTYSVSIPLGATINMAGAAITITVLTLAAVHTLGVPVDLPTALLLSVVASLCACGASGVAGGSLLLIPLACNMFGIPNDIAMQVVAVGFIIGVLQDSCETALNSSTDVLFTAAACQAEDERLANNALRS
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HRPB_ECOLI
Sequence: MSSLPVAAVLPELLTALDCAPQVLLSAPTGAGKSTWLPLQLLAHPGINGKIILLEPRRLAARNVAQRLAELLNEKPGDTVGYRMRAQNCVGPNTRLEVVTEGVLTRMIQRDPELSGVGLVILDEFHERSLQADLALALLLDVQQGLRDDLKLLIMSATLDNDRLQQMLPEAPVVISEGRSFPVERRYLPLPAHQRFDDAVAVATAEMLRQESGSLLLFLPGVGEIQRVQEQLASRIGSDVLLCPLYGALSLNDQRKAILPAPQGMRKVVLATNIAETSLTIEGIRLVVDCAQERVARFDPRTGLTRLITQRVSQASMTQRAGRAGRLEPGISLHLIAKEQAERAAAQSEPEILQSDLSGLLMELLQWGCSDPAQMSWLDQPPVVNLLAAKRLLQMLGALEGERLSAQGQKMAALGNDPRLAAMLVSAKNDDEAATAAKIAAILEEPPRMGNSDLGVAFSRNQPAWQQRSQQLLKRLNVRGGEADSSLIAPLLAGAFADRIARRRGQDGRYQLANGMGAMLDANDALSRHEWLIAPLLLQGSASPDARILLALLVDIDELVQRCPQLVQQSDTVEWDDAQGTLKAWRRLQIGQLTVKVQPLAKPSEDELHQAMLNGIRDKGLSVLNWTAEAEQLRLRLLCAAKWLPEYDWPAVDDESLLAALETWLLPHMTGVHSLRGLKSLDIYQALRGLLDWGMQQRLDSELPAHYTVPTGSRIAIRYHEDNPPALAVRMQEMFGEATNPTIAQGRVPLVLELLSPAQRPLQITRDLSDFWKGAYREVQKEMKGRYPKHVWPDDPANTAPTRRTKKYS
What are the official names of this protein?
ATP-dependent RNA helicase HrpB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family.