PharMolix/UniProtQA huggingface dataset:
Protein: YCIU_ECOBW
Sequence: MDMDLNNRLTEDETLEQAYDIFLELAADNLDPADVLLFNLQFEERGGAELFDPAEDWQEHVDFDLNPDFFAEVVIGLADSEDGEINDVFARILLCREKDHKLCHIIWRE
What are the official names of this protein?
UPF0263 protein YciU.
What is the protein family that this protein belongs to?
Belongs to the UPF0263 family.
Protein: SCA2_RICS2
Sequence: MSTCLLTSSFLSTSARAASFKDLVSKTPAWEKHNSTQQQNIWKDLTPNEKIKKWQEAALVPSFTQAQNDLGIKYKETDLSSFLDNTRHKARQARAEILLYIERVKQQDFDTKKQEYINQGVVPTDIEAATNLGISYDPSKIDNNVEHDQKVRRAEKDKKAVIELYISSINRDIKYKHYVDNDIIPEMQEVRTALNMNKDEAQSFVASIRTEIMENAKGQYIADSHIPTEKELKKKFGISRDDNRDGYIKSIRLKVMDKEKPQYIADSHIPTEKELEQKFGADKGEATNYIASIATQMMLGKKSYYIDNNIIPNADELMNEFKIGPVKTASYINQIRAGIEANQFLNNNDTTKPSTGRSQKKSGSKNDHWYMSNQSIHNTGTSSRIFTGREKKQRYFFDPISTFKTHFNTKANKGNLTQSQHSINRIIQQEENIEEFKNLIKTDPIIALTLQVDSSYKQEAVTTILSDFNDDTIQRVLFSNDKGQLDFNTNIDVKNRPILQELLENSSSEEKTKFAERIQDYATRNISNSQFEEKARLDLIKLAASKDKSSVENFLTLQLELKNIMQPYIVNSVYILTPEIVKEINIELKNKGLIRDSLTKDYMIKLAKEVSNHTLNSVIKVILSDSNILSNETNKILGLAVGNNANNLEQTQSGIPNPPPLPLNGGIPNPPPLPLNGSMPPPPPLHSQGFSSNSKHFDLNQLQTEYPHIHSLYIQFTHNTTVQSKAPLQPTASSATSTVRSTPETAYAKLYAEYRTETGGTKANDLQDQLIKRQADLTNVIRQILTESYANQGADEKTLLNLFSISTPEIAEKAKEAFNTLAQDQYIKDITVNGKKTITSEEIIKNLFNEDTDDAVKRILLSSCKISEELKRPIKLQFNQSELIRELQGKQNPFEQLEFAYINAKNFDQDIFGNRVDELINNPNILTIVQQATFLITEDTNLRKTINSDQAQAKLDDLRTAILSTIKFEELITANLPQHDFIAIVKEKDPELLKEFLKATTLKVTGNNNLDQLRLALPSFKGMSNEQIRILSNKLKMPIILKALKECSQEKATKYIHTGNMPPPPPPLPDSQDLELAYLTSLGITKFNANTSTLKTTPKTYHFSSDIALRYKEFTLSGQKSAGYKAKYSDADLLKKAIVESVAFEHSKNLSKAHQNNKYFEQIQEAVDTMYSSFIGPRTEIGQKIHNIYTSKLLELTKDKEFIKYVEDNIILSKKLTEAFTSADSDFIDSRTGLGQKIHDIYIQQLTKYPEEEVKEAFNTANPDFIGPRTEIGQEVHNIYKSQLLELTKDQELSLFTQQVLAESTELERKYGSDIQSGNSNNEKKVGRLDQEKLQSFKQENEATNDASSTKDDTQPEDSNKKSEQSDSKTALSPRLLSSNDSKNDKSSDDKKSLLALRSSDEDDTGYATDEEELEESNSTTNEELEESNSTTNEELEESNSTTNEELEESNSTTNEELKKDVVLESEDEAIDVSFKTEAITEQDEVTQRQQISDDTSGKVAILVQATSTLHKPVHYNINDRLTVAAIGAGDEETSINRGVWISGLYGINKQRIWKNIPKYQNRTTGITIGIDAEFINSHDVIGIAYSRLESQIKYNKKLGKTTVNGHLLSIYSLKELIKGFSLQTITSYGHNYIKNRSKNINNIIGKYQNNNLSFQTLLNYKYRTKYDLHFIPNIGFQYDYSRASNYKEYNVDIENLMIQKKSNQLFESSLGGKIVFKPIVTTNNIVLTPSLYGNIEHHFNNKNTKVNAKATFKGQTLQETIITLKQPKLGYNIGSNILMSRKNINVLLEYNYYTHRKYQSHQGLIKLKVNL
What are the official names of this protein?
Putative surface cell antigen sca2.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: TRUA_DICT6
Sequence: MINWKVELSYIGKDFWGFQKQPGKRTVQGELEKVLKLLFDEDIKVIGAGRTDAGVHALGQVVNFKTKESKNFSCDKLYKVLNKLLPGDIKIKKVEIVDDNFHARYSAKRRWYIYVIYNNEEKNLFLRDYCWWINKPLDKDLLNLSANLFKGIHDFRNFCVIENYDNTNVEIYESFWYFKEDLLIYFVSAPFFLRKMVRFIVGSMVEVGLKKKELEDLEKYLKDRKEERFSSPAPASGLYLFKIDY
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: RIMM_HELPS
Sequence: MVSMLLVGRIGKSVGLNGGLRLHLESDFPECLKKGVKVSVAPLNAFFCTSSFKGYTIHSYEHAKNLLFLETIHTPEKAKELTNLGLFMSEAESKKLCVLKDGEFFYCDLVGLSVVEENETLGKVVEIQRISQIDYFMVETARSLVEKGLAKIFLIPYRDFYIKEILLQDKKITTNNAKTLLENS
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK33_CYACA
Sequence: MVKHKAARICINLECIDCKSNLHKRSNGISRYTTIKNRKNNPSRMELKKFCPYCNMRTIHKEIK
What are the official names of this protein?
50S ribosomal protein L33, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FTSK_CHLPN
Sequence: MIRERKKSRHPRLPTLPLAAKASLYLFFACFSGLSLWSFHRDQPCTQNWIGLLGWSFSSFLLYFFGAAAFFIPLYFLWLSFLYFRRTPRPLFFYKAAAFLSLPFCSAILLSMLSPVGTLPALLDTRLPKFILGNNPPVSYVGGIPFYLFYEGQSFCLKHLIGSVGTALIFGFVMLFSVLYLCGGIALLKKKTFQDGVKKAFCSFFQTCFKNLKKLINRRNYLPKPSVPFVSKNPFSCTKSQPSPRRVSETIILDGSISPLPQEEIPGSKKESFFLTPHPCKRFLTKFVEPQENKAKEGKTIALSSTPTVVRESKGKERAALPKLKSLAVPENDLPQYHLLSKNREARPESLQAELERKALILKQTLTSFGIDADLGNICSGPTLAAFEVLPHSGVKVQKIKSLENDIALKLQASSIRIIAPIPGKAAVGIEIPTPFPQAVNFRDLLEDYQKTNRKLQIPLLLGKKANGDNLWADLATMPHLIIAGTTGSGKSVCINTIVMSMIMTTLPSEIKLVIIDPKKVELTGYSQLPHMLSPVITESREVYNALVWLVKEMESRYEILRYLGLRNIQAFNSRTRNKTIEASYDREIRETMPFMVGIIDELSDLLLSSSQDIETPIIRLAQMARAVGIHLILATQRPSREVITGLIKANFPSRISFKVSNKVNSQIIIDEPGAENLMGNGDMLVLLPSVFGTIRAQGAYICDEDINKVIQDLCSRFPTQYVIPSFHAFDDSDSDNSGEKDPLFAQAKTLILQTGNASTTFLQRKLKIGYARAASLIDQLEEARIIGPSEGAKPRQILIQNPLEG
What is the function of this protein?
Essential cell division protein that coordinates cell division and chromosome segregation.  The N-terminus is involved in assembly of the cell-division machinery.  The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region.  Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity).
What are the official names of this protein?
DNA translocase FtsK.
What is the protein family that this protein belongs to?
Belongs to the FtsK/SpoIIIE/SftA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Located at the septum.
Protein: GADC_ECOL6
Sequence: MATSVQTGKAKQLTLLGFFAITASMVMAVYEYPTFATSGFSLVFFLLLGGILWFIPVGLCAAEMATVDGWEEGGVFAWVSNTLGPRWGFAAISFGYLQIAIGFIPMLYFVLGALSYILKWPALNEDPITKTIAALIILWALALTQFGGTKYTARIAKVGFFAGILLPAFILIALAAIYLHSGAPVAIEMDSKTFFPDFSKVGTLVVFVAFILSYMGVEASATHVNEMSNPGRDYPLAMLLLMVAAICLSSVGGLSIAMVIPGNEINLSAGVMQTFTVLMSHVAPEIEWTVRVISALLLLGVLAEIASWIVGPSRGMYVTAQKNLLPAAFAKMNKNGVPVTLVISQLVITSIALIILTNTGGGNNMSFLIALALTVVIYLCAYFMLFIGYIVLVLKHPDLKRTFNIPGGKGVKLVVAIVGLLTSIMAFIVSFLPPDNIQGDSTDMYVELLVVSFLVVLALPFILYAVHDRKSKANTGVTLEPINSQNAPKGHFFLHPRARSPHYIVMNDKKH
What is the function of this protein?
Involved in glutaminase-dependent acid resistance.  Exchanges extracellular glutamate (Glu) for intracellular gamma-aminobutyric acid (GABA) under acidic conditions.  The ability to survive the extremely acidic conditions of the stomach is essential for successful colonization of the host by commensal and pathogenic bacteria.
What are the official names of this protein?
Glutamate/gamma-aminobutyrate antiporter, Glu/GABA antiporter.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Glutamate:GABA antiporter (GGA) (TC 2.A.3.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y165_STAES
Sequence: MFKVVICDDERIIRQGLKQMIPWKEYHFTTIYTATDGVEALSLIRQHQPELVITDIRMPRKNGVDLLDDIKDLDCQVIILSSYDDFEYMKAGIQHHVLDYLLKPVDHTQLEHILDILVQRLLERPHSTNDDAAYYTAFQPLLKIDYDDYYVNQILSQIKQHYHKKVTVLDLINPIVVSESYAMRTFKEHVGITIVDYLNRYRILKSLHLLDQHYKHYEIAEKVGFSEYKMFCYHFKKYLHMSPSDYNKLSK
What is the function of this protein?
Probable member of the two-component regulatory system SE_0166/SE_0165.
What are the official names of this protein?
Uncharacterized response regulatory protein SE_0165.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7S_ECO55
Sequence: MPKKNEAPASFEKALSELEQIVTRLESGDLPLEEALNEFERGVQLARQGQAKLQQAEQRVQILLSDNEDASLTPFTPDNE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_BURPS
Sequence: MPNAYKRVLLKLSGEALMGDDAFGINRATIERMVADIAEVVRLGTQLAVVIGGGNIFRGVAGGAAGMDRATADYMGMLATMMNALALQDAMRHAGIEARVQSALRMDQVVEPYIRPRAIRQLEEGKVVIFAAGTGNPFFTTDTAAALRGSEVGAEVVLKATKVDGVYSADPKKDPSATRYSSISFDEAIGRNLQVMDATAFALCRDQKLPIRVFSINKPGALKRIVQGEDEGTLVHV
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHG25_MOUSE
Sequence: MSLKLPRNWDFNLKAEASKIARSRSVMTGEQMAAFHPPTTPNPLERPIKVGWLKKQRSIVKNWQQRYFVLRAQQLYYYKDEEDSKPQGCMYLPGSTVKEIATNPEEAGKFVFEVIPASSDQNRIGQDSYVLMASSQVEMEEWVKFLRRVAGTPSGAVFGQRLDETVAYEQKFGPHLVPILVEKCAEFILEHGVSEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPEPVVPWSQYEGFLLCGQLMNADEAKAQQELVKQLSTLPRDNYNLLSYICRFLHEIQLNCAVNKMSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDAPISPPAQKNDAKKAPVPRSSVGWDATEDPPLSRTDSFSNTASSPDATSPTGPLPSDQHQEDSGKAPRENPGDWKMQSRKRTQTLPNRKCFLTSAFQGTTSSKLEIFKNEFWSPSSEAKAGEGHRRTMSQDLRHLSNDQRTSTYDNVPTSPQSQGNPAGALSPPASDSKRDALVSTDSEMEAGSKNSGEDDLDSLQRTVQSLQKEIETQKQVYEEQIKNLEKENYDVWAKVVRLNEELERERKKFAALEISLRNVERSREDVEKRNRVLEEEVKEFVKSMEKPKTKTDP
What is the function of this protein?
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
What are the official names of this protein?
Rho GTPase-activating protein 25, Rho-type GTPase-activating protein 25.
Protein: 3CPI_HETMG
Sequence: GSICLEPKVVGPCTAYFPRFYFDSETGKCTPFIYGGCEGNGNNFETLHACRAICRA
What is the function of this protein?
Serine protease inhibitor that inhibits trypsin (Ki=73. 8 nM) and chymotrypsin (Ki=993 nM).
What are the official names of this protein?
PI-stichotoxin-Hmg3c, PI-SHTX-Hmg3c, Kunitz-type serine protease inhibitor HMGS2.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family. Sea anemone type 2 potassium channel toxin subfamily.
Protein: SYR_KINRD
Sequence: MTPAELSAALRDALTAAVAAGELTLDPADVPAEVRVERPKNRDHGDWATSVALQLAKKAGLPPREVAALVQRRLLEVEGVRAVDIAGPGFLNVTLDAAAAGELARSVVEAGPAFGRSATPTGERINLEFVSANPTGPIHLGGTRWAAVGDSLARVLEAAGATVTREYYFNDHGAQIDRFARSLLARANDEPAPEDGYGGDYVTDIAAAVLAEAPGLLDLPREEQQEVFRREGVELMFAEIRQSLAEFGVEFDVYFHEDSLHTSGAVGRAVQKLRDLGRIYEADGATWLRTSDFGDDKDRVVIKSDGHPAYISGDLAYYLDKRERGFDRCVLMLGADHHGYVPRMMAMCAAFGDTPGVNLEILIGQMVNLLKDGVPVRMSKRAGTVVTMEDLVEAVGVDAARYSLVRSSVDSSIDIDLDLLTRRSNDNPVFYVQYAHARTANVAVNAAAAGVRREDAFDPSLLTEETESLLLAALAEFPAVVARAGELREPHRVARYLEELAGRFHKFYDACRVTPRAGEEVTDVHRTRLWLNDATRQVLANGLGLLGVSSPDRM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPA11_DICDI
Sequence: MGSQFSVLNRKWLIERSIMIEKRKRRSNKLIKILMMGNENSAKSTFAKKVKSIYQSDKIENSDANSILPYIKLYLSNSFKDVIKFIQQHPQSPDTKPMVSTQLGIIAWDKLSSFNYIPFNFKPTKELAKYIYDICHDPLFKSYIYPIISSKREDAFYLIENCKRMSNDDYIPNDEDIIRCSKNNQSGVFDTKLEIGKSEFVFVDTGNQKCDRKKWVHQFEDVDIILFFLALDEFDLPPDEIKSQSQSVHDCYNKLNENILVFDEIVNNHFFSNTPVIVLFNKKEQLIEKLKTTTFSQHYPDYQSNSNNPNDIFSFISNQFKLRDHFPLNKRLFIHSFNSSDTNQIDFFQYVKKILEDTI
What are the official names of this protein?
Guanine nucleotide-binding protein-like alpha-11 subunit.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family.
Protein: GTSE1_HUMAN
Sequence: MDDPKKEDILLLADEKFDFDLSLSSSSANEDDEVFFGPFGHKERCIAASLELNNPVPEQPPLPTSESPFAWSPLAGEKFVEVYKEAHLLALHIESSSRNQAAQAAKPEDPRSQGVERFIQESKLKINLFEKEKEMKKSPTSLKRETYYLSDSPLLGPPVGEPRLLASSPALPSSGAQARLTRAPGPPHSAHALPRESCTAHAASQAATQRKPGTKLLLPRAASVRGRSIPGAAEKPKKEIPASPSRTKIPAEKESHRDVLPDKPAPGAVNVPAAGSHLGQGKRAIPVPNKLGLKKTLLKAPGSTSNLARKSSSGPVWSGASSACTSPAVGKAKSSEFASIPANSSRPLSNISKSGRMGPAMLRPALPAGPVGASSWQAKRVDVSELAAEQLTAPPSASPTQPQTPEGGGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTNQFKIPKFSIGDSPDSSTPKLSRAQRPQSCTSVGRVTVHSTPVRRSSGPAPQSLLSAWRVSALPTPASRRCSGLPPMTPKTMPRAVGSPLCVPARRRSSEPRKNSAMRTEPTRESNRKTDSRLVDVSPDRGSPPSRVPQALNFSPEESDSTFSKSTATEVAREEAKPGGDAAPSEALLVDIKLEPLAVTPDAASQPLIDLPLIDFCDTPEAHVAVGSESRPLIDLMTNTPDMNKNVAKPSPVVGQLIDLSSPLIQLSPEADKENVDSPLLKF
What is the function of this protein?
May be involved in p53-induced cell cycle arrest in G2/M phase by interfering with microtubule rearrangements that are required to enter mitosis.  Overexpression delays G2/M phase progression.
What are the official names of this protein?
G2 and S phase-expressed protein 1, GTSE-1, Protein B99 homolog.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Associated with microtubules.
Protein: ENDA_HALVD
Sequence: MQGRLEDGVVHLPGDARQRFHDSRGYGRPTGGDDLEVAPVEAAHLLSRDDIDGVDGMGLRELLARTGTTLDFVVYKDLRDRGFYLSPAREGWPGVADAADADFLVYPRGKGPWDGEVEHRVRVVGERESIPVSSLGEVVLAIVDEDGDLTYFDTEGDDPEGTAAEDLPADLDAELLSDRALVWDGVDRLYQRGFFGQRLYGRNADSGPLQLSLLEAAYLARADALAIDEADVVSRGRDVEGDRFDRRLAVYAALREAKTVPKSGFKFGSDFRVYTEFESVDDLSHSEFLVRVVAPDHTFVPRDLSLDVRLAGGVRKRMVFALTDDNGEIDWLSVSRLTP
What is the function of this protein?
Endonuclease that removes tRNA introns.  Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron.  The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini.  Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
What are the official names of this protein?
tRNA-splicing endonuclease, tRNA-intron endonuclease.
What is the protein family that this protein belongs to?
Belongs to the tRNA-intron endonuclease family. Archaeal long subfamily.
Protein: MURA_YERPE
Sequence: MDKFRVQGRTRLSGEVTISGAKNAALPILFAALLAEEPVELQNVPKLKDIDTTIKLLSQLGTKIERNNGSVFVDASAVNEFCAPYDLVKTMRASIWALGPLVARFGQGQVSLPGGCAIGARPVDLHITGLEQLGAEIKLEEGYVKASVNGRLKGAHIVMDKVSVGATVTIMSAATLAEGTTVIENAAREPEIVDTANFLNTLGAKISGAGTDRITIEGVTRLGGGVYRVLPDRIETGTFLVAAAISGGKVVCRQTRPDTLDAVLAKLREAGADIEVGDDWISLDMQGKRPKAITFRTAPHPGFPTDMQAQFSLLNLVAEGTGVITETIFENRFMHVPELIRMGAHAEIESNTVICYGVEQLSGAQVMATDLRASASLVLAGCIAEGVTIVDRIYHIDRGYERIEDKLRALGAKIERVKGE
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EMP1_PONAB
Sequence: MLVLLAGIFVVHIATVIMLFVSTIANVWLVSNTVDASVGLWKNCTNISCSDSLSYASEDALKTVQAFMILSIIFCVIALLVFVFQLFTMEKGNRFFLSGATTLVCWLCILVGVSIYTSHYANRDGTQYHHGYSYILGWICFCFSFIIGVLYLVLRKK
What are the official names of this protein?
Epithelial membrane protein 1, EMP-1.
What is the protein family that this protein belongs to?
Belongs to the PMP-22/EMP/MP20 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DDLA_BRUSU
Sequence: MASGKMRIVVLFGGRSAEHDVSVLSATNVMNALDPAKYEAVPVFVTRAGQWLLSRFVNGALEKPSSGAELCLVPGGCGRAIVVPDAGAPYEADKIDIIFPVLHGLHGEDGAVQGLAQVARVPLAGCGIPGSANALDKDIAKRLVNEAGLSTAKSVTITREEVPAFSALEQALGLPIFIKPARQGSSVGVHKVVTEADYQAAMSDGFTYDDKLLAEEFIQAREVECGVLEDEGGALFVSRAGEIVPAESHCFYSYDAKYIDADGTEIKVPAELPEQVENEIRAIATRAFRVLGCDSMARVDFFVTADRRIVLNEINTIPGFTDMSMYSKVMAVSGVSYPEIINRLVAHGLARGS
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase A, D-Ala-D-Ala ligase A, D-alanylalanine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_BRUSU
Sequence: MSRRHKAEKREINPDPKFGDLVITKFMNAVMLHGKKSVAESIVYGALDAIEAKAKSEPVALFHQALDNVAPHIEVRSRRVGGATYQVPVDVRPERRQALAIRWLINAARGRNETTMVDRLSGELLDAANNRGSAVKKREDTHRMAEANRAFSHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: Y220_SYNP2
Sequence: MNYSPRIQDIPASERPRERLVAVGAKYLSNAELIAILISTGDRHRNLSAVGLAQFILQTCSQGKRDPFDMLRHTTPQELTSIPGVGLAKAAQILAGIELGKRIFQAKPSEKIIVDSPEAAAIALSNDLMWQDQERFAVLCLDVKNTLIATRVVTIGLATETLAHPREIFREVIKHGATRLIIAHNHPSGNVDPSPEDLQLTERLLQSAQILGIPLLDHLILGRDNFGSLRQKTALWDSYPQPE
What are the official names of this protein?
UPF0758 protein SYNPCC7002_A0220.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: OPT1_YEAST
Sequence: MSTIYRESDSLESEPSPTPTTIPIQINMEEEKKDAFVKNIDEDVNNLTATTDEEDRDPESQKFDRHSIQEEGLVWKGDPTYLPNSPYPEVRSAVSIEDDPTIRLNHWRTWFLTTVFVVVFAGVNQFFSLRYPSLEINFLVAQVVCYPIGRILALLPDWKCSKVPFFDLNPGPFTKKEHAVVTIAVALTSSTAYAMYILNAQGSFYNMKLNVGYQFLLVWTSQMIGYGAAGLTRRWVVNPASSIWPQTLISVSLFDSLHSRKVEKTVANGWTMPRYRFFLIVLIGSFIWYWVPGFLFTGLSYFNVILWGSKTRHNFIANTIFGTQSGLGALPITFDYTQVSQAMSGSVFATPFYVSANTYASVLIFFVIVLPCLYFTNTWYAKYMPVISGSTYDNTQNKYNVTKILNEDYSINLEKYKEYSPVFVPFSYLLSYALNFAAVIAVFVHCILYHGKDIVAKFKDRKNGGTDIHMRIYSKNYKDCPDWWYLLLQIVMIGLGFVAVCCFDTKFPAWAFVIAILISLVNFIPQGILEAMTNQHVGLNIITELICGYMLPLRPMANLLFKLYGFIVMRQGLNLSRDLKLAMYMKVSPRLIFAVQIYATIISGMVNVGVQEWMMHNIDGLCTTDQPNGFTCANGRTVFNASIIWSLPKYLFSSGRIYNPLMWFFLIGLLFPLAVYAVQWKFPKFKFAKHIHTPVFFTGPGNIPPSTPYNYSLFFAMSFCLNLIRKRWRAWFNKYNFVMGAGVEAGVAISVVIIFLCVQYPGGKLSWWGNNVWKRTYDNDYKKFYTLKKGETFGYDKWW
What is the function of this protein?
High affinity transporter for glutathione.  Also transports tetra- and pentapeptides like the opioids leucine enkephalin (Tyr-Gly-Gly-Phe-Leu) and methionine enkephalin (Tyr-Gly-Gly_Phe-Met) across the cell membrane.
What are the official names of this protein?
Oligopeptide transporter 1, High affinity glutathione transporter 1.
What is the protein family that this protein belongs to?
Belongs to the oligopeptide OPT transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: H18_MOUSE
Sequence: MAPGSVSSVSSSSFPSRDTSPSGSCGLPGADKPGPSCRRIQAGQRNPTMLHMVLEALKAREARQGTSVVAIKVYIQHKYPTVDTTRFKYLLKQALETGVRRGLLTRPAHSKAKGATGSFKLVPKPKTKKACAPKAGRGAAGAKETGSKKSGLLKKDQVGKATMEKGQKRRAYPCKAATLEMAPKKAKAKPKEVRKAPLKQDKAAGAPLTANGGQKVKRSGSRQEANAHGKTKGEKSKPLASKVQNSVASLAKRKMADMAHTVTVVQGAETVQETKVPTPSQDIGHKVQPIPRVRKAKTPENTQA
What is the function of this protein?
May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure.  Essential for meiotic maturation of germinal vesicle-stage oocytes.  The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte.  The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure.  The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling.
What are the official names of this protein?
Histone H1.8, Histone H1oo, Oocyte-specific histone H1, Oocyte-specific linker histone H1.
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Chromosome. Note=In the germinal vesicle oocyte, localizes to the condensed chromosomes. In the 1-cell embryo found in condensed maternal metaphase chromatin but not in the sperm head. Following second polar body extrusion, detected in the swollen sperm head as well as in the second polar body. Reduced expression in the nucleus in 2-cell embryo is seen as compared to 1-cell embryo.
Protein: SYH_METMJ
Sequence: MLQKPRGTRDFLPDEMERRRLIERRMRDAARRWGYREVCTPDFEHLELFTMKSGEGIIQEMYVFEDKGGRKMTLRPEVTAAVLRMYVNEGKVLPKPLRWCYFADCFRYERPQKGRYRQFWQFGVELIGADTASADAEVIMLADDTLRSTGVTFDLHVGHLAPMKHLLSGLDPGDQRAIMAYLDKHDQKGLEAVLFGKNLTHLAEPLAALGECRTVSEVFEVAGDVPERARIEETFTLLESQEIDYRPDFGIARGLDYYTGMVFEGFAKNLGAENQILGGGTYRLAHLFGGDDVASCGFAIGFDRVMVSIGDFELAHEPVVGVVCTPEGRARALEVARAFREAGVRAEADLMQRGMGAQVSHAAKTADFAAVLGKREVEAGTVTLKNLHSGEQQERSLEEAIAEVARHGAC
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHK1_SCHPO
Sequence: MAQKLDNFPYHIGREIGTGAFASVRLCYDDNAKIYAVKFVNKKHATSCMNAGVWARRMASEIQLHKLCNGHKNIIHFYNTAENPQWRWVVLEFAQGGDLFDKIEPDVGIDEDVAQFYFAQLMEGISFMHSKGVAHRDLKPENILLDYNGNLKISDFGFASLFSYKGKSRLLNSPVGSPPYAAPEITQQYDGSKVDVWSCGIILFALLLGNTPWDEAISNTGDYLLYKKQCERPSYHPWNLLSPGAYSIITGMLRSDPFKRYSVKHVVQHPWLTSSTPFRTKNGNCADPVALASRLMLKLRIDLDKPRLASSRASQNDSGFSMTQPAFKKNDQKELDRVEVYGALSQPVQLNKNIDVTEILEKDPSLSQFCENEGFIKRLAKKAKNFYEICPPERLTRFYSRASRETIIDHLYDSLRLLAISVTMKYVRNQTILYVNLHDKRKCLLQGVIELTNLGHNLELINFIKRNGDPLEWRKFFKNVVSSIGKPIVLTDVSQN
What is the function of this protein?
Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA (PubMed:8497322).  May also negatively regulate cell cycle progression during unperturbed cell cycles.  Binds to and phosphorylates CDC25.  This leads to negative regulation of CDC25 and prevents mitotic entry (PubMed:9278510).
What are the official names of this protein?
Serine/threonine-protein kinase chk1, Checkpoint kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: MINE_ECO55
Sequence: MALLDFFLSRKKNTANIAKERLQIIVAERRRSDAEPHYLPQLRKDILEVICKYVQIDPEMVTVQLEQKDGDISILELNVTLPEAEELK
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: RS182_STRAW
Sequence: MPRKPVRKVASTPRPNPLDQNGITYIDYKDTDLLRKFLSDRGKIRSRRVTRVTAQQQRLLARAVKNAREMALLPYSSR
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: FLGH_AQUAE
Sequence: MLYLFFALIFIISCSTKVESKKKYTYSFPKTYKEEKPTRGSLFKSPQSAYLYGSVRASEVGDVIYIRVIESINAIESVSTNVGRSTSFSNAISSFFGVHPATLKNLGAGGKSSFASKGGSKFQQSGVLTTTLAGRVVKVFPNGTMLVEAKKYIEVNGVKREFLLRGIVRPEDIDSNNTVTSDKIADMEIFFEGRGYIVRGGEPGWLAKIFAILFPF
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.