PharMolix/UniProtQA huggingface dataset:
Protein: PSAA_NEOYE
Sequence: MAISSKEQETKKVKISVDKNPVDTSFEKWAQPGHFSRTLAKGPRTTTWIWNLHADAHDFDSQTSSLEEVSRKIFSAHFGQLSVIFLWLSGMYFHGARFSNYVAWLSNPTGIKPSAQVVWPIVGQEILNGDVGGGFQGVQVTSGWFQLWRASGITTEFQLYCTAIGGLAMAALMLFAGWFHYHKAAPKLEWFQNVESMMNHHLAGLLGLGCLGWTGHQIHLSLPINKLLDSGVSPQEIPLPHEFLINRELMAQLYPSFSKGLVPFFTLNWAEYSDFLTFKGGLNPVTGGLWLSDTAHHHLALAVLFLAAGHMYRTNWGIGHSMKEILEAHKGPFTGNGHEGLYEILTTSWHAQLAINLAMMGSLSIIVAHHMYAMPPYPYIATDYPTQLSLFTHHMWIGGFCIVGAGAHASIFMVRDYNPAENYNNLRSSSRHRDAIVSHLNWVCIFLGFHSFGLYIHNDTMRALGRSQDMFSDTAIQLQPIFAQWVQSIHTLAPGNTAPNALATASYAFGGDIVSVGNKVAMMPISLGTADFLVHHIHAFTIHVTVLILVKGFLFSRNSRLIPDKANLGFRFPCDGPGRGGTCQVSGWDHVFLGLFWMYNSLSVAIFHFSWKMQSDVWGSVSPSGNVSHITGGNFAQSAITINGWLRDFLWAQASQVIQSYGSALSAYGLIFLAAHFVWAFSLMFLFSGRGYWQELIESIVWAHNKIKVAPAIQPRALSITQGRAVGVAHYLLGGIGTTWAFFLARIISVG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PSI-A, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ARRS_LITPI
Sequence: MSGDKKSRSVIYKKTSRDKAVSVYLGKRDYVDHIESVDPVDGVVFVDPDLLKGKKVYVTLTCAFRYGNEDIDVIGLTFRKDLFFARIQVYPPVEDVKCLTKVQERLMKKLGNNAYPFVMAFPDYLPCSVSLQPAMSDVNKACGVDFEIKAFSASNLEDRYHKKNSVRLLIRKIQYAPDQPGPTPRAETSWQFFMSDKPLHLTASLAKEVFYHGETITVAVTVTNNSEKTVKKISTSVEQTANVVLYSSDFYTKTVAFDESDEKVSPKSTYKHTFTLLPLLAYNREKREIALDGKLKHEDTNLASSTLLKEGIDRTVMGILVDYKIKVTLTVSGLLGDMTSSEVSTELPFILMHPKPDSGAKESEQEEDFVFEDFARDHLKDELQPEEKEEEEEDEK
What is the function of this protein?
Arrestin is one of the major proteins of the ros (retinal rod outer segments); it binds to photoactivated-phosphorylated rhodopsin, thereby apparently preventing the transducin-mediated activation of phosphodiesterase.
What are the official names of this protein?
S-arrestin, Retinal S-antigen, S-AG, Rod photoreceptor arrestin.
What is the protein family that this protein belongs to?
Belongs to the arrestin family.
Protein: BIOC_DECAR
Sequence: MTSAIKPKAGTRPSKARIRQSFERAAPTYDDAAAIQRRICIRLAEGLPDIAPTHLLDAGCGTGYAQANLQTRFPDAHRVALDLSPGMLQRVATPCCRVAGDLEHLPLADSSLDLYWSSLAVQWCDLAVALREAHRTLRPGGVIALASLGPATFHELRHAFADVDDHRHTLAFHSPGEIRQLASLAGLAAIDIKKSTEIAHYPDFKTLLRAVKAIGANQLGDGRRTSLMSRSSFQLAESACEQLRTPAGLPLTYDVIYLYARK
What is the function of this protein?
Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM).  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.
What are the official names of this protein?
Malonyl-[acyl-carrier protein] O-methyltransferase, Malonyl-ACP O-methyltransferase, Biotin synthesis protein BioC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: DEFB6_MOUSE
Sequence: MKIHYLLFAFILVMLSPLAAFSQLINSPVTCMSYGGSCQRSCNGGFRLGGHCGHPKIRCCRRK
What is the function of this protein?
Has potent antibacterial activity against E. coli (ATCC 25922).
What are the official names of this protein?
Beta-defensin 6, BD-6, mBD-6, Defensin, beta 6.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TADA1_BOVIN
Sequence: MATFVSELEAAKKNLSEALGDNVKQYWANLKLWFKQKISKEEFDLEAHRLLTQDNVHSHNDFLLAILTRCQILVSTPEGAGSLPWTGGSAAKPGKPKGKKKLSSVRQKFDHRFQPQNPLSGAQQFVAKDPQDDDDLKLCSHTMMLPTRGQLEGRMIVTAYEHGLDNVTEEAVSAVVYAVENHLKDILSSVVSRRKAYRLRDGHFKYAFGSNVTPQPYLKNSVVAYNSLIESPPALSAPFAGQNPASHPPPDDAEQQAALLLACSGDTLPASLPPVNMYDLFEALQVHREVIPTHTVYALNIERIIMKLWHPNHEELQQDKVHRQRLAAKEGLLFC
What is the function of this protein?
Probably involved in transcriptional regulation.
What are the official names of this protein?
Transcriptional adapter 1, Transcriptional adapter 1-like protein.
What is the protein family that this protein belongs to?
Belongs to the TADA1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SIX3D_LEIHE
Sequence: MKLLLLLTISASMLIEGLVNADGYIRGGDGCKVSCVINHVFCDNECKAAGGSYGYCWGWGLACWCEGLPAEREWDYETNTCGGKK
What is the function of this protein?
Depressant insect beta-toxins cause a transient contraction paralysis followed by a slow flaccid paralysis.  They bind voltage-independently at site-4 of sodium channels (Nav) and block action potentials, primarily by depolarizing the axonal membrane and suppressing the sodium current.  This depressant toxin is active only on insects.  It is found in a relatively small amount in the venom, and its activity on insects is 10-fold higher compared to other known depressant toxins.
What are the official names of this protein?
Beta-insect depressant toxin Lqh-dprIT3d.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PURT_DESVM
Sequence: MVTIGTPNTPSATRILLLGSGELGREVAIEAMRLGVEVIAVDRYPNAPAMQVAHRSHVVSMLDGAALRRIIEAERPHCIVPEIEAIATETLLELEKEGFRVVPTARAARLTMDREGIRRLAAEELGLPTSPYRFAETEAEYREAVAAVGLPCVVKPVMSSSGKGQSTVRTEADVMKAWEYAQTGGRAGGGKVIVEGFVDFDYEITQLTVRHAGGTTFCDPIGHLQKDGDYRESWQPHPMSQAALAESRRMAEAVTGALGGWGIFGVELFIKGDKVYFSEVSPRPHDTGLVTLISQNLSEFALHARAILGLPVPALRQNGPAASCVVLAEGDSMSPGYHGIEAALAEPDTGLCLFGKPEVHGKRRMGVALALGASIEEARAKARRAAAAVQVEL
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: TRUD_WOLSU
Sequence: MERLYYLNHAPIDFHFAQTPRDFVVEEIPLYPFSGAGEHLVLKIRKRNLSTFELVDILSSHLGIKSREIGYAGLKDKSALTLQHLSIPAKFGDKLEAFDHPEVKILEQVRHENKIRIGHLKGNRFFIRLKKLSPLNSLKIQGVLEEIKRWGIPNYFGYQRFGNDGNNHEIGRKIAHGEQRVTSPKRRTFLLSAYQSKLFNEWLKERIKLSKILAEFTPSEASRLAPMIPVEQLKALQKQPHPFKILPGEILHHYPHGKIFVAEDMEEESRRFVEKDIVPAGLLSGTKAKSSEGIAHLYEAPFIDEKIQEQGSRRLAWIFPEDLEYRYIEEEAHGELNFYLPKGSYATVLIEELAHREIKID
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: THEM4_HUMAN
Sequence: MLRSCAARLRTLGALCLPPVGRRLPGSEPRPELRSFSSEEVILKDCSVPNPSWNKDLRLLFDQFMKKCEDGSWKRLPSYKRTPTEWIQDFKTHFLDPKLMKEEQMSQAQLFTRSFDDGLGFEYVMFYNDIEKRMVCLFQGGPYLEGPPGFIHGGAIATMIDATVGMCAMMAGGIVMTANLNINYKRPIPLCSVVMINSQLDKVEGRKFFVSCNVQSVDEKTLYSEATSLFIKLNPAKSLT
What is the function of this protein?
Has acyl-CoA thioesterase activity towards medium and long-chain (C14 to C18) fatty acyl-CoA substrates, and probably plays a role in mitochondrial fatty acid metabolism.  Plays a role in the apoptotic process, possibly via its regulation of AKT1 activity.  According to PubMed:11598301, inhibits AKT1 phosphorylation and activity.  According to PubMed:17615157, enhances AKT1 activity by favoring its phosphorylation and translocation to plasma membrane.
What are the official names of this protein?
Acyl-coenzyme A thioesterase THEM4, Acyl-CoA thioesterase THEM4, Carboxyl-terminal modulator protein, Thioesterase superfamily member 4.
What is the protein family that this protein belongs to?
Belongs to the THEM4/THEM5 thioesterase family.
Protein: YNG2_AZOBR
Sequence: MALPWLFNSSPRAGGPSACACLWPRRYPAAGLRTVPVRVSIQPDGDVLVALPRAAVEDGRFDAAAARRLTAQMRRLVGRVTTTNPLWGIDALQALGEAVTALAGLCSGGVLLWNGFEQMTTGRWAHSAATLALLAAPAALAKLRPWLLGAVAPKLFPLALKAGERIVRI
What are the official names of this protein?
Uncharacterized 17.8 kDa protein in nodG 5'region, ORF 2.
Protein: SYS_METNO
Sequence: MHDIRVIRENPAAFDEGLAKRGLEPLSAELIALDDARKAAISAAQGAQERRNALSKEIGAAKKAKDEARAQDLMAEVARLKDEAPALEAAADAAAKALDARLAAIPNTPKAEVPLGRDEHDNVEYRRFEGRGRAEAGRQHFELGEATGLMDFEAAAKLSGARFVVLKGHLARLERALGQFMLDLHTTEHGYTEVAPPLLVRDEVMFGTAQLPKFRDDQFAAMPGSVEAEGGAPTRWLIPTAEVPLTNLVRESILSEDELPLRFTALTPCFRAEAGAAGRDTRGMLRQHQFTKVELVSVTTPEQSDEEHERMLASAEAVLKKLDLPYRVVTLCTGDMGFASQKTYDIEVWLPGQGTFREISSCSVCGDFQARRMDARFRRREGRGVAHVHTLNGSGVAVGRALIAVMENYQNPDGSVTVPSALVPYMGGITRIEGPHA
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAE_TRICV
Sequence: MISRGSKVRILRKESYWFNQVGTIATIDQSGIRYPAVVRFENVNYSGTNTNNFALEELIEVSEVETKSKEA
What is the function of this protein?
Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase.
What are the official names of this protein?
Photosystem I reaction center subunit IV, PSI-E.
What is the protein family that this protein belongs to?
Belongs to the PsaE family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: RL28_PROMH
Sequence: MSRVCQVTGKRPVSGNNRSHALNATKRRFLPNLHSHRFWVESEKRFVTLRVSAKGMRVIDKKGIESVLADLRARGEKY
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: CLIC2_HUMAN
Sequence: MSGLRPGTQVDPEIELFVKAGSDGESIGNCPFCQRLFMILWLKGVKFNVTTVDMTRKPEELKDLAPGTNPPFLVYNKELKTDFIKIEEFLEQTLAPPRYPHLSPKYKESFDVGCNLFAKFSAYIKNTQKEANKNFEKSLLKEFKRLDDYLNTPLLDEIDPDSAEEPPVSRRLFLDGDQLTLADCSLLPKLNIIKVAAKKYRDFDIPAEFSGVWRYLHNAYAREEFTHTCPEDKEIENTYANVAKQKS
What is the function of this protein?
Can insert into membranes and form chloride ion channels.  Channel activity depends on the pH.  Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions.  Modulates the activity of RYR2 and inhibits calcium influx.
What are the official names of this protein?
Chloride intracellular channel protein 2, XAP121.
What is the protein family that this protein belongs to?
Belongs to the chloride channel CLIC family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Single-pass membrane protein. Note=Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain.
Protein: TVA4_HUMAN
Sequence: MRQVARVIVFLTLSTLSLAKTTQPISMDSYEGQEVNITCSHNNIATNDYITWYQQFPSQGPRFIIQGYKTKVTNEVASLFIPADRKSSTLSLPRVSLSDTAVYYCLVGD
What is the function of this protein?
V region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition (PubMed:24600447).  Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.  Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333).  Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.  In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.  The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462).  The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement.  This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells.  Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585).
What are the official names of this protein?
T cell receptor alpha variable 4.
What are the subcellular locations of this protein?
Cell membrane.
Protein: PFKA_BLOFL
Sequence: MIKKIGVLTSGGDSPGMNAAIRGVVRAGLSEGIEVYGIYDGYLGLFQNRMMLLSYCSVSDIINKGGTVLGSSRFPELKKDMIRSVVMNNISKSHLDALVIIGGDGSYIGARRLSDLGCPCIGIPGTIDNDVAGTDYTIGYFTALETIIEAIDRLRDTSSSHQRISIVEVMGRYCGDLTISAAIAGGCEFVIIPELKFQMQDLVDKIKLNISKGKKHAIVAITERICNVFDLAQYIENETGKETRATVLGHIQRGGKPVAYDRILASRMGAYSIELLLKGYGRHCIGIENEKLVHHDINDATKYMRRSFRQDLLTTAKKLC
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MP70_MYCKA
Sequence: MKSSMAATGLVAAAVVGLAVATSPTAAAADLVGPGCADYAAANPSGPASVEGMSQVPVAVAASNNPMLTTLTSAVSGRLNPQVNLVDTLNNGQYTVFAPTDPAFDKLPASTIVQLKTDSNL
What are the official names of this protein?
Immunogenic protein MPT70 analog.
What are the subcellular locations of this protein?
Secreted.
Protein: METXA_GLUOX
Sequence: MDISASPSIADGPVYTHQTVRLDSGLDLECGVHLAPLEVAYCTYGTLSPARDNAILVCHALTGDQYLAERNPLTGKPGWWSRMVGPGLPIDTDRYFVVCSNVLGGCMGTTGPRSICAETGKAWDSEFPPITMHDIVAAQAKLIDHLGIDRLFAVIGGSMGGMQALTWAADFPDRVFAAMPIATSPFHSAQNIAFNEVSRQAIFADPDWHDGHYRDFGAIPARGLGVARMMAHITYLSEEALSRKFGRRVRHDAATAVPASSSPSLFGEMFEVESYLRHQGSSFVRRFDANSYLTITRAMDYFDLAAEHDGDLANPFRKSQTRFCVVSFSSDWLFPTSQSRLLVRALNRAGANVSFVEIESDRGHDAFLLEEPDFDRTIRGFIAGAAEHAALKAGER
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TATA_RICCK
Sequence: MGMSFSHLLIVLLIIFVLFGAGKLPQVMSDLAKGLKAFKDGMKDDGNDNDRKNN
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: HSP82_ORYSJ
Sequence: MASETETFAFQAEINQLLSLIINTFYSNKEIFLRELISNSSDALDKIRFESLTDKSKLDAQPELFIHIVPDKASNTLSIIDSGVGMTKSDLVNNLGTIARSGTKEFMEALAAGADVSMIGQFGVGFYSAYLVAERVVVTTKHNDDEQYVWESQAGGSFTVTRDTSGEQLGRGTKITLYLKDDQLEYLEERRLKDLVKKHSEFISYPISLWTEKTTEKEISDDEDEEEKKDAEEGKVEDVDEEKEEKEKKKKKIKEVSHEWNVMNKQKPIWLRKPEEITKEEYAAFYKSLTNDWEEHLAVKHFSVEGQLEFKAILFVPKRAPFDLFDTRKKQNNIKLYVRRVFIMDNCEELIPEWLSFVKGIVDSEDLPLNISREMLQQNKILKVIRKNLVKKCVELFFEIAENKEDYNKFYEAFSKNLKLGIHEDSTNRTKIAELLRYHSTKSGDELTSLKDYVTRMKEGQSEIYYITGESKKAVENSPFLEKLKKKGYEVLYMVDAIDEYAVGQLKEFEGKKLVSATKEGLKLDESEDEKKRQEELKEKFEGLCKVIKEVLGDKVEKVVVSDRVVDSPCCLVTGEYGWTANMERIMKAQALRDSSMAGYMSSKKTMEINPENSIMDELRKRADADKNDKSVKDLVMLLFETALLTSGFSLEDPNTFGTRIHRMLKLGLSIDEDESAEADADMPPLEDDAGESKMEEVD
What is the function of this protein?
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction.  Undergoes a functional cycle that is linked to its ATPase activity.  This cycle probably induces conformational changes in the client proteins, thereby causing their activation.  Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity).
What are the official names of this protein?
Heat shock protein 81-2, HSP81-2, Heat shock protein 90.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIM44_YEAS2
Sequence: MIIRAPIRTKTKSFRGDQMDFKFPSNESLPRGTLEEYHLNNHHLLNDVFAAENGVSRDEDGNSQILSDYTSTSNTNTNSGYSSNGYYSFANISDNTTSSPRIVINQNETARLTSSDSNKSDFFASHDFPGNDSLHYSSSSVVKNQLHSMEAIPEGNITGSISTAFQTIPTADNVSYDIAPSSASSLLPRKSTSKSAILPSTQEAKPMTKLNMEKDIKTIELNNSVVPKPKKKLNRVPTIRRVESSRFSNSRYSSSVSSKSSSSRCSLKRSKAIRCKGGLLYYFTSLGIKIKKKLRKLRLVLRRRLFSYNVQKVPSATNSKTTKSKANINNKSKKRGTNLVNKNSNSTPRLDTKFKANHPQSEDSKVGSNTPRSPLVSYTPSLRRTNSSIRRAASILTASATMTPANNKNSFISVPDNVSHAVTRNSSMYSRSRLVRSKPSTALNAIARQPSIVVENKVIPLSMNRYSIKEEDEYVIDTSSMRELSPVNSVCSSDYDRESSESYSNYADAMETTEVDNKDRVECNNEIQNVNANNEETSNEESYNLMKHYLSTVIAQRIMLRVQIARIQNNKSNVVYMNKSAETNSTIYEDLADSLLTEYEADGSSSQIFDGVSVRADEEEEEDEDDEDDEEEEEENDDEEDEEDEEDDEDDEEEEEKRKEGEGRNLAKEVDELAELSPMRKQSDLSITLRSPFAMLNSAYSNSIISLPTGVVKRSLTLPVGMKI
What are the official names of this protein?
Altered inheritance of mitochondria protein 44.
What is the protein family that this protein belongs to?
Belongs to the AIM44 family.
What are the subcellular locations of this protein?
Bud neck.
Protein: DAPH_STRP4
Sequence: MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLGNVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEIGDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAEPVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQTQQKTALEDALRTL
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. DapH subfamily.
Protein: 3L24_NAJME
Sequence: IRCFITPDVTSQICADGHVCYTKTWCDAWCTSRGKRVDLGCAATCPTVKTGVDIKCCSTDNCNPFPTRNRP
What is the function of this protein?
Binds with high affinity to muscular (alpha-1-beta-1-gamma-delta/CHRNA1-CHRNB1-CHRNG-CHRND) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission (PubMed:33672715).  Ranges of nAChR inhibition are in nanomolar (competitive binding with alpha-bungarotoxin gives Ki=1. 66 nM on muscle nAChR and Ki=4. 84 nM on alpha-7) (PubMed:33672715).  Also shows moderate inhibition on GABA(A) alpha-1-beta-3-gamma-2 receptor (GABRA1-GABRB3-GABRG2) (IC(50)=0. 68 uM), and a lower inhibition on alpha-1-beta-2-gamma-2 (GABRA1-GABRB2-GABRG2) and alpha-3-beta-2-gamma-2 (GABRA3-GABRB2-GABRG2) (PubMed:33672715).
What are the official names of this protein?
Long neurotoxin Tx-NM3-1.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Long-chain subfamily. Type II alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SDE2_HUMAN
Sequence: MAEAAALVWIRGPGFGCKAVRCASGRCTVRDFIHRHCQDQNVPVENFFVKCNGALINTSDTVQHGAVYSLEPRLCGGKGGFGSMLRALGAQIEKTTNREACRDLSGRRLRDVNHEKAMAEWVKQQAEREAEKEQKRLERLQRKLVEPKHCFTSPDYQQQCHEMAERLEDSVLKGMQAASSKMVSAEISENRKRQWPTKSQTDRGASAGKRRCFWLGMEGLETAEGSNSESSDDDSEEAPSTSGMGFHAPKIGSNGVEMAAKFPSGSQRARVVNTDHGSPEQLQIPVTDSGRHILEDSCAELGESKEHMESRMVTETEETQEKKAESKEPIEEEPTGAGLNKDKETEERTDGERVAEVAPEERENVAVAKLQESQPGNAVIDKETIDLLAFTSVAELELLGLEKLKCELMALGLKCGGTLQERAARLFSVRGLAKEQIDPALFAKPLKGKKK
What is the function of this protein?
Plays a role in ribosome biogenesis by enabling SNORD3- and SNORD118-dependent cleavage of the 47S rRNA precursor (PubMed:34365507).  Binds ncRNA (non-coding RNA) including the snoRNAs SNORD3 and SNORD118 (PubMed:34365507).
What are the official names of this protein?
Splicing regulator SDE2, Replication stress response regulator SDE2.
What is the protein family that this protein belongs to?
Belongs to the SDE2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MURI_STRPJ
Sequence: MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGPRPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASAAIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSVTKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLLNYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: PRV7_DANRE
Sequence: MAMKNLLKDDDIKKALDQFKAADSFDHKKFFDVVGLKALSADNVKLVFKALDVDASGFIEEEELKFVLKGFSADGRDLTDKETKAFLAAADKDGDGKIGIDEFEALVHE
What is the function of this protein?
In muscle, parvalbumin is thought to be involved in relaxation after contraction.  It binds two calcium ions (By similarity).
What are the official names of this protein?
Parvalbumin-7, Parvalbumin alpha, Parvalbumin-4a.
What is the protein family that this protein belongs to?
Belongs to the parvalbumin family.
Protein: RL1_SERP5
Sequence: MAKLTKRMRVIRDKVDATKQYDITEAVALLKELATAKFVESVDVAVNLGIDARKSDQNVRGATVLPNGTGRSVRVAVFAQGPNAEAAKAAGAELVGMEDLADQIKKGEMNFDVVIASPDAMRVVGQLGQILGPRGLMPNPKVGTVTPNVAEAVKNAKAGQVRYRNDKNGIIHTTIGKVDFESDKLKENLEALLVALKKAKPSQAKGVYIKKVSLSTTMGAGVAIDQSGLTAVAN
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: RS18_SHISS
Sequence: MARYFRRRKFCRFTAEGVQEIDYKDIATLKNYITESGKIVPSRITGTRAKYQRQLARAIKRARYLSLLPYTDRHQ
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.