PharMolix/UniProtQA huggingface dataset:
Protein: ATPL_CALBD
Sequence: MTALAAGIAMLAGLGVGIGIGIATGKASESIGRQPEAFGRIFPLFLIGAALAEAVAIYSLVIAFMLISKI
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HEMA_I85A3
Sequence: MNTQILILTLVAAIHTNADKICLGHHAVSNGTKVNTLTERGVEVVNATETVERRTIPRICTKGKKAIDLGQCGLLGIITGPPQCDQFLEFTADLIIERREGNDVCYPGKFVNEEALRQILRESGGINKETTGFTYSGIRTNGVTSACRRLGSSFYAEMKWLLSNTDNAAFPQMTKSYKNTRNEPALIVWGIHHSGSATEQTKLYGSGNKLITVGSSNYQQSFVPSPGARPQVNGQSGRIDFHWLILNPNDTVTFSFNGAFVAPDRVSFFKGKSMGIQSEVPVDTNCEGECYHNGGTITSNLPFQNVNSRAVGKCPRYVKQKSLLLATGMKNVPEIPKKREKRGLFGAIAGFIENGWEGLVDGWYGFRHQNAQGEGTAADYKSTQSAIDQITGKLNRLIEKTNQQFELIDNEFTEVEKQIGNVINWTRDSITEVWSYNADLLVAMENQHTIDLADSEMNKLYERVRRQLRENAEEDCTGCFEIFHKCDDDCMASIRNNTYDHSTYREEAMQNRVKIDPVKLSSGYKDVILWFSLGASCFLLLAIAMGLVFMCVKNGNMRCTICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: RL4_ACIET
Sequence: MQLELLNEQGQAASKVDVPETVFDRQYNEDLIHQIVVAYQANARQGTRAQKDREQVKHSTKKPFKQKGTGNARAGMTSSPLWRGGGRIFPNLPEENFSQKINKKMYRAGMASILSQLAREGRLAVVDSLKLDTPKTKVLADKFKAMNLQSVMVIADEVDENLYLASRNLKNVFVTEPRYADPVSLVHYKKVLVTKGAIDKLKEMFA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: COX2_LYCCU
Sequence: MAYPFQLGLQDATSPIMEELLHFHDHTLMIVFLISSLVLYIISLMLTTKLTHTSTMDAQEVETVWTILPAIILILIALPSLRILYMMDEINNPSLTVKTMGHQWYWSYEYTDYEDLNFDSYMIPTQELKLGELRLLEVDNRVVLPMEMTVRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQTTLMAMRPGLYYGQCSEICGSNHSFMPIVLEMVPLSYFETWSAVMV
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DPO3B_STAAN
Sequence: MMEFTIKRDYFITQLNDTLKAISPRTTLPILTGIKIDAKEHEVILTGSDSEISIEITIPKTVDGEDIVNISETGSVVLPGRFFVDIIKKLPGKDVKLSTNEQFQTLITSGHSEFNLSGLDPDQYPLLPQVSRDDAIQLSVKVLKNVIAQTNFAVSTSETRPVLTGVNWLIQENELICTATDSHRLAVRKLQLEDVSENKNVIIPGKALAELNKIMSDNEEDIDIFFASNQVLFKVGNVNFISRLLEGHYPDTTRLFPENYEIKLSIDNGEFYHAIDRASLLAREGGNNVIKLSTGDDVVELSSTSPEIGTVKEEVDANDVEGGSLKISFNSKYMMDALKAIDNDEVEVEFFGTMKPFILKPKGDDSVTQLILPIRTY
What is the function of this protein?
Confers DNA tethering and processivity to DNA polymerases and other proteins.  Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA.  Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity.  The beta chain is required for initiation of replication as well as for processivity of DNA replication.
What are the official names of this protein?
Beta sliding clamp, Beta clamp, Sliding clamp, Beta-clamp processivity factor, DNA polymerase III beta sliding clamp subunit, DNA polymerase III subunit beta.
What is the protein family that this protein belongs to?
Belongs to the beta sliding clamp family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DOLP_SALTY
Sequence: MKAFSPLAVLISALLLQGCVAAAVVGTAAVGTKAATDPRSVGTQVDDGTLELRVSSALSKDEQIKKETRINVTAYQGKVLLVGQSPNSELSARAKQIAMGVEGTTEVYNEIRQGQPIGLGTASNDTWITTKVRSQLLTSDQVKSSNVKVTTENGEVFLLGLVTEREGKAAADIASRVSGVKRVTTAFTYIK
What is the function of this protein?
Plays an important role in maintaining outer membrane integrity (PubMed:30201701).  Contributes to virulence (PubMed:30201701).
What are the official names of this protein?
Outer membrane lipoprotein DolP.
What is the protein family that this protein belongs to?
Belongs to the lipoprotein DolP family.
Protein: RS2_STRT2
Sequence: MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQQTVKMVDTAYEFVREAAANDAVILFVGTKKQAAEAVAEEATRAGQYYINHRWLGGTLTNWNTIKKRIARLKEIKQMEADGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDVIYIVDPHKEQIAVKEAKKLGIPVVAMVDTNADPDEIDVIIPANDDAIRAVKLITSKMADAIIEGNQGEDASADFQEAAAADSIEEIVEVVEGDNN
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: LF2_EBVB9
Sequence: MAEAYPGGAHAALASRRSSFRNSLRRLRPTEKPDTSFMRGVWKYEIFPSYVRVTNKQVLQLDAQCQELPPCPSVGQILSFKLPSFSFNTTTYGSRYFTVAFLFFGAEDNEVFLKPFFVMHSDQDIVLSVLNPRSLFIEKGKFTWYIVPIRLVKNPYLYLQILPGQSDIQLTRSCTQSGDKLNTSEPQIFLSGSPVTSQDECLPYLLAQHTPPFLKSYARIHTFPGKVCPVNAIRRGKGYVRVSVDTPDLKREGPLNVKVGMTLLDDVIIAFRYNPYPKSHWRWDGESTDIRYFGSPVIIPPNFITELEYNNTYEAPLSSKITAVVVSHSSNPVFYVYPQEWKPGQTLKLTVRNISNNPITIVTGQSMAQAFFIYAGDPSISTIMRRYIQRQGCALTLPGNIVVESSSLPTFERINKTFNGNIVASEGTL
What is the function of this protein?
Prevents the establishment of cellular antiviral state by blocking the cellular IRF7-mediated innate immunity.  May also inhibit viral replication by modulating BRLF1 activity.
What are the official names of this protein?
Protein LF2.
What is the protein family that this protein belongs to?
Belongs to the epstein-barr virus LF2 family.
Protein: GYRA_STAAU
Sequence: MAELPQSRINERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHPHGDSSIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVLPARFPNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGSIQMRSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNNLYKQTPLQTSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRESDTDKVAMESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELEAILADEEVLLQLVRDELTEIRDRFGDDRRTEIQLGGFEDLEDEDLIPEEQIVITLSHNNYIKRLPVSTYRAQNRGGRGVQGMNTLEEDFVSQLVTLSTHDHVLFFTNKGRVYKLKGYEVPELSRQSKGIPVVNAIELENDEVISTMIAVKDLESEDNFLVFATKRGVVKRSALSNFSRINRNGKIAISFREDDELIAVRLTSGQEDILIGTSHASLIRFPESTLRPLGRTATGVKGITLREGDEVVGLDVAHANSVDEVLVVTENGYGKRTPVNDYRLSNRGGKGIKTATITERNGNVVCITTVTGEEDLMIVTNAGVIIRLDVADISQNGRAAQGVRLIRLGDDQFVSTVAKVKEDAEDETNEDEQSTSTVSEDGTEQQREAVVNDETPGNAIHTEVIDSEENDEDGRIEVRQDFMDRVEEDIQQSLDEDEE
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGB_ANADE
Sequence: MADLLFEIGAEEIPAGFVPGALRQLEDDLAKALADARLAHGEVRAVGTPRRLAVWARDVAPKQTDARTEAFGPPVAQAYDAEGKPTPAATGFARSQGVEVSALVRAQTPKGERVAVTKVEKGRKAEQVLPALLERLVAGLRFRKAMRSRFDEVTFARPVRWMVALLGGRPLKVRHGEVASGKVTYGHRFLAPKAIALKGTPDDYLAKLRRAHVLADPEERRAALLAELARAGKEAGGKVRDDPALVEQVLYLVEEPSAVVGEFERSNLELPPEVVISEMRNHQRYFAVVDGKGRLKNRFVAVSATRVKDPAVARHGYERVLRARLADARFFFEEDRKRKLHERIEDLGRRTFQAKLGSELDRAQRIGAVASGLARALGKDALVADLLEASRLAKVDLNTGMVGEFPELQGTMGAHYARLEGLKPEIADAIEDHYKPIGAAEEMPRSDLGALVAVADRLHSLVGIIGVGEKATGAADPFGLRRAAIGILRIVIARGYHLSLATAVEQTLDALAGVKLAAGRALVAEQVLDFLRGRVRAAWTERFDADLVEAVLAAGSDDVVDARRRLEALAEAKARPDFGSLAVAFKRVANIQEKAGGPGAAAVDPALLRDPAEQDLLAALEKVEQEVGARRAARDYPAVLRTVATLEPAVARFFDDVLVMAEDPALRANRLGLMRRVGALFSDLADFRKIQAEAPAQARAG
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPS25_YEAST
Sequence: MSALPPVYSFPPLYTRQPNSLTRRQQISTWIDIISQYCKTKKIWYMSVDGTVINDNELDSGSTDNDDSKKISKNLFNNEDIQRSVSQVFIDEIWSQMTKEGKCLPIDQSGRRSSNTTTTRYFILWKSLDSWASLILQWFEDSGKLNQVITLYELSEGDETVNWEFHRMPESLLYYCLKPLCDRNRATMLKDENDKVIAIKVV
What is the function of this protein?
Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.  The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation.  The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex.
What are the official names of this protein?
Vacuolar protein-sorting-associated protein 25, ESCRT-II complex subunit VPS25.
What is the protein family that this protein belongs to?
Belongs to the VPS25 family.
What are the subcellular locations of this protein?
Cytoplasm. Endosome membrane; Peripheral membrane protein.
Protein: HIS8_GEOUR
Sequence: MIPLRKNIARMAGYVPGYQPEDPAAYIKLNTNENAYPPSPKVLEAIMAEVGEGLRRYPDAASRAGREAAARLYGFLPEWIVMANGSDEVLNNLIRAFADEGDEIAYVYPSYSYYATLAEIQGARVKTYGLTDDWKLANFPERYDGKIFFLTNPNAPYGFTFSREFIEELAGRVAGMLVVDETYADFAGDTALDLVRKYENVVVTRTLSKSYSLAGMRLGLAVARPEVIAALDKIRDHYNLDRLAQAAAVAALGDQDYFREAVRKICETRDWFSAELRKLRYSVIPSSGNYVFTTPPDRDGARVYQGLFDRKILVRHFSDPNLAHGLRISIGTREEMEKTMEALREIG
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: RSMF_SERP5
Sequence: MAKPACVFLPPAFLEATRAIMPADLSMDDFIAACQRPLRRSLRVNTLKISVTDFLTLVQDYDWRLEPIPWCAEGFWIERGDEELRLGSAAEHLSGLFYIQEASSMLPVSALFAGAEAPSRVLDVAAAPGSKTTQIAALMNNQGGIVANEYSASRVKVLHANISRCGVKNVALTHFDGRVFGAALPESFDAILLDAPCSGEGVVRKDPDAMSNWSPESVTAIADTQRELIDSAFHALAPGGVMVYSTCTLNAQENQQIVNGLLATYGDAVSIEPLGDLFPGAKQALTAEGFLHVFPQIYDSEGFFVARLRKHHSVPPLAKPSYKLGKFPFTPLSGKDSAEIAQAAAASGLAWDKTSRLWARDKEIWLFPAELEALVNKIRFSRIGLKLAERFTKGYRWQHEAVIALAVADGKQRFELDATLAQEWFHGRDLYPEPPPQTDECIVTYQQQPLGIAKRIGSRIKNNLPRELVRDGVLDFHQ
What is the function of this protein?
Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase F, 16S rRNA m5C1407 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmF.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P85A_HUMAN
Sequence: MSAEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGYNETTGERGDFPGTYVEYIGRKKISPPTPKPRPPRPLPVAPGSSKTEADVEQQALTLPDLAEQFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSSSNLAELRQLLDCDTPSVDLEMIDVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENLIKVIEILISTEWNERQPAPALPPKPPKPTTVANNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR
What is the function of this protein?
Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane.  Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues.  Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB.  Likewise, plays a role in ITGB2 signaling (PubMed:17626883, PubMed:19805105, PubMed:7518429).  Modulates the cellular response to ER stress by promoting nuclear translocation of XBP1 isoform 2 in a ER stress- and/or insulin-dependent manner during metabolic overloading in the liver and hence plays a role in glucose tolerance improvement (PubMed:20348923).
What are the official names of this protein?
Phosphatidylinositol 3-kinase regulatory subunit alpha, PI3-kinase regulatory subunit alpha, PI3K regulatory subunit alpha, PtdIns-3-kinase regulatory subunit alpha, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha, PI3-kinase subunit p85-alpha, PtdIns-3-kinase regulatory subunit p85-alpha.
What is the protein family that this protein belongs to?
Belongs to the PI3K p85 subunit family.
Protein: TOM92_ARATH
Sequence: MAAKRIGAGKSGGGDPNILARISNSEIVSQGRRAAGDAVEVSKKLLRSTGKAAWIAGTTFLILVVPLIIEMDREAQINEIELQQASLLGAPPSPMQRGL
What is the function of this protein?
Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins.  Together with TOM20 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the translocation pore (By similarity).
What are the official names of this protein?
Mitochondrial import receptor subunit TOM9-2, Mitochondrial import receptor subunit TOM22 homolog 2, Translocase of outer membrane 22 kDa subunit homolog 2, Translocase of outer membrane 9 kDa subunit TOM9-2.
What is the protein family that this protein belongs to?
Belongs to the Tom22 family.
Protein: ATPA_HERA2
Sequence: MAVTAEDILSRLKASIQQPVGGDPTAVNVGTVASVGDGVARISGLRDVMASELLEFKQTKSGETVMGIALNLEKDNVAAVILGDYLEIEEGDLVRSTGKIISVPVGQELLGRVVDPLGRPLDGKGPISASKTREVERIAPGVIERKSVSQPVQTGILAIDALIPIGRGQRELIIGDRQTGKTAIAIDTIINQRGQGMVCVYVAIGQKRSKVAQTITTLEQNGAMDYTIVVNASASESAALQYIAPYSGCAIAEEVMEVGVTVDGNLVKDALIIYDDLSKHAVAYRQVSLLLRRPPGREAYPGDVFYLHSRLLERAARLSEVNGGGSITALPIIETQANDVSAYIPTNVISITDGQIFLESDLFYAGQRPALNVGISVSRVGSSAQTKAMKTVAGKMKLELAQFRELAAFAMFASDLDAGTKAQIERGQRLSELLKQPQYQPIALEDQVIILWVAGNGFLDDVPVARINDFKRDFWQFIHSSYAEVGRAIASEKVLSEATIASLRKAVTEFKQTASYK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: YQGF_XANOR
Sequence: MPEAGAILPDGTVLGFDVGSRRIGVAVGTALGAGARAVAVINVHASGPDWDALDRVHKEWRPDGLVVGDPLTLDDKHQPARKRAHAFARQLRERYALPVVLIDERSSSVEAAQRFARERADGRKRRRDAEALDAMAAAVIVERWLAAPDQATLLP
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CGHR_STEMA
Sequence: DFCMGSMRVAALLYYAAPSGRPHSSWRPGKGLDAPQHCTGMPRGSVECPVTLPWPAPCPAHPRRCPRPTPKKTCSVRDDADTGWMDAWTLEKSERCLSGVRNMHLTSAILIFT
What are the official names of this protein?
Chorionicgonadotropic hormone-like receptor, CGH-R.
Protein: CATC_PONAB
Sequence: MGPGPASLLAALLLLLSGDRAVRCDTPANCTYLDLLGTWVFQVGSSGSQRDVNCSVMGPQEKKVVVHLQKLDTAYDDLGNSGHFTIIYNQGFEIVLNDYKWFAFFKYKEEGSKVTTYCNETMTGWVHDVLGRNWACFTGKKVGTASENVYVNTAHLKNSQEKYSNRLYKYDHNFVKAINAIQKSWTATTYKEYETLTLGDMIRRSGGHSRKIPRPKPAPLTAEIQQKVLHLPTSWDWRNIHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTSNSQTPILSPQEVVSCSQYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSEYHYVGGFYGGCNEALMKLELVHHGPMAVAFEVYDDFLHYKKGIYHHTGLRDPFNPFELTNHAVLLVGYGTDSASGMDYWIVKNSWGTGWGEDGYFRIRRGTDECAIESIAVAATPIPKL
What is the function of this protein?
Thiol protease.  Has dipeptidylpeptidase activity.  Active against a broad range of dipeptide substrates composed of both polar and hydrophobic amino acids.  Proline cannot occupy the P1 position and arginine cannot occupy the P2 position of the substrate.  Can act as both an exopeptidase and endopeptidase.  Activates serine proteases such as elastase, cathepsin G and granzymes A and B.
What are the official names of this protein?
Dipeptidyl peptidase 1, Cathepsin C, Cathepsin J, Dipeptidyl peptidase I, DPP-I, DPPI, Dipeptidyl transferase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: BETI_ECOUT
Sequence: MPKLGMQSIRRRQLIDATLEAINEVGMHDATIAQIARRAGVSTGIISHYFRDKNGLLEATMRDITSQLRDAVLNRLHALPQGSAELRLQAIVGGNFDETQVSSAAMKAWLAFWASSMHQPMLYRLQQVSSRRLLSNLVSEFRRELPRQQAQEAGYGLAALIDGLWLRAALSGKALDKPLAHSLTRHFITQHLPTD
What is the function of this protein?
Repressor involved in the biosynthesis of the osmoprotectant glycine betaine.  It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator BetI.
Protein: ATPG_STRPZ
Sequence: MAGSLSEIKAKIISTEKTSKITSAMRMVSSAKLVKSEQAARDFQIYASKIRQITTDLLKSELTIGSDNPMLVSRPVKKTGYIVITSDKGLVGGYNSKILKSVMDMITEYHADGDYEIISIGSVGSDFFKARGMNVAFELRGLADQPSFEQVRQIISQSVDMFVNEIFDELYVCYNHHVNSLTSQVRVQQMLPISDLVADEAAEEGVTGFELEPNRQDILDQLLPQFTESLIYGAIIDAKTAEHAAGMTAMQTATDNAKNVINDLTIQYNRARQAAITQEITEIVAGANALE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: BPNT1_HUMAN
Sequence: MASSNTVLMRLVASAYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPKLTIIGEEDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGLLDNVTVLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAFGFQLKEVPAGKHIITTTRSHSNKLVTDCVAAMNPDAVLRVGGAGNKIIQLIEGKASAYVFASPGCKKWDTCAPEVILHAVGGKLTDIHGNVLQYHKDVKHMNSAGVLATLRNYDYYASRVPESIKNALVP
What is the function of this protein?
Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP.  Has 1000-fold lower activity towards inositol 1,4-bisphosphate (Ins(1,4)P2) and inositol 1,3,4-trisphosphate (Ins(1,3,4)P3), but does not hydrolyze Ins(1)P, Ins(3,4)P2, Ins(1,3,4,5)P4 or InsP6.
What are the official names of this protein?
3'(2'),5'-bisphosphate nucleotidase 1, Bisphosphate 3'-nucleotidase 1, PAP-inositol 1,4-phosphatase, PIP.
What is the protein family that this protein belongs to?
Belongs to the inositol monophosphatase superfamily.
Protein: RL10_BORBR
Sequence: MSLNRQEKAVVIEEVSAQVAKAQSIVIAEYRGLDVASVTVLRKTARESGVYLRVLKNTLVRRAVAGTAFEPLSEQLTGPLIYGISADPVAAAKVLAGFAKSNDKLVIKAGSLPNSLLTQDGVKALATMPSREELLSKLLGTMQAPIAQFVRTLNEVPTKFARGLAAVRDQKAAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: LAEA_GIBF5
Sequence: MVVMPPQNSVNESEGRYLQDGFWQHGRFYGSWKPGKYLFPIDSEELNRLDIFHKVFLLARDNKPFLAPIRRTSPRIMDIGTGTGIWAINVAEECLSDAQIMAVDLNQIQPALIPPGFMPKQYDIEEPSWGPLLADCDLIHMRMLLGSIQTDLWPQVYHNAFEHLTPGIGFLEHIEVDWIPRCDDDERPANSAFVKWAELFLDGMDRFNRSVRVIPQEHRQMLEATGFTDVKQEVIKAYVCPWSADRNEREIARWFNIGLSHSLEAMSLKPLIEKLGFEAEDVRELCERAKRETCVLRYHTYCNIHVWTARKPGPQQ
What is the function of this protein?
Methyltransferase that performs automethylation (By similarity).  No other methyl-accepting substrate has been identified yet (By similarity).  Component of the velvet transcription factor complex that acts as a global regulator for secondary metabolite gene expression (PubMed:20572938).  Controls the expression of the gibberellins gene clusters, but does not affect bikaverin production (PubMed:20572938).  Controls the expression of the fusaric acid gene cluster (PubMed:24389666).  Acts as a virulence factors during infection, most likely through activation of gibberellins biosynthesis (PubMed:20572938).
What are the official names of this protein?
Secondary metabolism regulator LAE1, Methyltransferase LAE1, Velvet complex subunit LAE1.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. LaeA methyltransferase family.
What are the subcellular locations of this protein?
Nucleus.