PharMolix/UniProtQA huggingface dataset:
Protein: COAX_PSEA7
Sequence: MILELDCGNSLIKWRVIDGGGGRSVAGGLADSDEALVEQLSLRRGLPVRACRLVSVRSEQETSQLIARLERLFPVSVLVAAPGRQLAGVRNGYLDYQRLGLDRWLALVAGHHLAQKACLVIDLGTAVTSDLVAANGTHLGGYICPGMSLMRSQLRTHTRRIRYDDTEARRAMGSLHPGQATAEAVERGCLLMLRGFVREQYAMACELLGADCEIFLTGGDAELVRDELARARIIPDLVFVGLALACPIE
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAS1_DROSI
Sequence: MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLLVFAVNSAKSFEDIGTYREQIKRVKDAEEVPMVLVGNKCDLASWNVNNEQAREVAKQYGIPYIETSAKTRMGVDDAFYTLVREIRKDKDNKGRRGRKMNKPNRRFKCKML
What is the function of this protein?
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.  Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells.  During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis.
What are the official names of this protein?
Ras-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: ICCE_TALVA
Sequence: MADLHLAKSITLRCGLTLPNRLAKTAIAESIAPRNMLIDEGFHRVYAPWAEGGWGMVLTGHVQVDSMHLGTHTDPAVNADFSDDQIVGSWKVWAAVCNRHGTPTIMQLNHPGRQAPIGAGTSGVFAKNISASAVPMDIGSGLLARAVSKIVFGTPREMTVDDIGKLVRQFARAARLASQSGFAGVELHASHGYLLAQFLSAATNRRKDAYGGTPANRARIVVEIIKAVRAEVPASFCVGIILTAVHGSASTEEFQSFIEQAQLICDAGVDFIEISGGTFETPSMFIGPEKRGKAYDWDNQEAFFLDFAQAIRPHLGTVPLLLTGGFRSCHAMEAAVKRGDCDMIGLARPAVVNPLLPKTVVFNPEVNKSGDTKLHATRTPAPWYIKLFGITALNVHMDNAWYVGRLQTLAKTGR
What is the function of this protein?
NADH-dependent flavin oxidoreductase; part of the gene cluster that mediates the biosynthesis of ilicicolin H, a 4-hydroxy-2-pyridonealkaloid that has potent and broad antifungal activities by inhibiting the mitochondrial respiration chain (PubMed:30905148).  IccE acts as an epimerase and catalyzes the conversion of 8-epi-ilicicolin H into the final product ilicicolin H (PubMed:30905148).  The biosynthesis of ilicicolin H starts with formation of the tetramic acid by the hybrid PKS-NRPS synthetase iccA with the partnering trans-enoyl reductase iccB since iccA lacks a designated enoylreductase (ER) domain.  The cytochrome P450 monooxygenase iccC then catalyzes the ring expansion of the tetramate to the acyclic 2-pyridone.  The pericyclase iccD further converts the acyclic 2-pyridone into 8-epi-ilicicolin H.  Finally, the epimerase iccE converts 8-epi-ilicicolin H into ilicicolin H via epimerization.  IccA to iccE are sufficient for ilicicolin H biosynthesis and the roles of the remaining enzymes, iccF, iccG and iccH within the pathway have still to be determined (PubMed:30905148) (Probable).
What are the official names of this protein?
NADH-dependent flavin oxidoreductase iccE, Epimerase iliE, Ilicicolin H biosynthesis cluster protein E.
What is the protein family that this protein belongs to?
Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.
Protein: 4CL1_ORYSJ
Sequence: MGSMEQQQPESAAPATEASPEIIFRSKLQDIAITNTLPLHRYCFERLPEVAARPCLIDGATGGVLTYADVDRLSRRLAAALRRAPLGLRRGGVVMSLLRNSPEFVLSFFAASRVGAAVTTANPMSTPHEIESQLAAAGATVVITESMAADKLPSHSHGALTVVLIDERRDGCLHFWDDLMSEDEASPLAGDEDDEKVFDPDDVVALPYSSGTTGLPKGVMLTHRSLSTSVAQQVDGENPNIGLHAGDVILCALPMFHIYSLNTIMMCGLRVGAAIVVMRRFDLAAMMDLVERHRVTIAPLVPPIVVAVAKSEAAAARDLSSVRMVLSGAAPMGKDIEDAFMAKLPGAVLGQGYGMTEAGPVLSMCLAFAKEPFKVKSGACGTVVRNAELKIIDPDTGKSLGRNLPGEICIRGQQIMKGYLNNPEATKNTIDAEGWLHTGDIGYVDDDDEIFIVDRLKEIIKYRGFQVAPAELEALLITHPSIADAAVVGKQIEPEIGEIPVAFVAKTEGSELSEDDVKQFVAKEVIYYKKIREVFFVDKIPKAPSGKILRKELRKQLQHLQQEA
What is the function of this protein?
Involved in the phenylpropanoid metabolism by mediating the activation of a number of hydroxycinnamates for the biosynthesis of monolignols and other phenolic secondary metabolites (PubMed:21807887, PubMed:23246835).  Catalyzes the formation of CoA esters of cinnamate, 4-coumarate, caffeate and ferulate (PubMed:21807887, PubMed:23246835).  Is more efficient with substrates in the following order: ferulate > 4-coumarate > cinnamate > caffeate (PubMed:21807887).  Cannot convert sinapate to its corresponding CoA ester (PubMed:21807887, PubMed:23246835).  Follows a two-step reaction mechanism, wherein the carboxylate substrate first undergoes adenylation by ATP, followed by a thioesterification in the presence of CoA to yield the final CoA thioester (By similarity).
What are the official names of this protein?
4-coumarate--CoA ligase 1, 4CL 1, Os4CL1, (E)-ferulate--CoA ligase, 4-coumaroyl-CoA synthase 1.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: TTCA_CROS8
Sequence: MSEIQEISKKEQYNLNKLQKRLRRNVGEAIADYNMIEEGDRIMVCLSGGKDSYTMLEILRNLQQSAPVNFSLVAVNLDQKQPGFPEHILPEYLSSLGVEYKIVEENTYGIVKEKIPEGKTTCSLCSRLRRGILYRTATELGATKIALGHHRDDILQTLFLNMFYGGKMKGMPPKLMSDDGKHIVIRPLAYCREKDIERFSQAKGFPIIPCNLCGSQPNLQRQVIADMLRDWDKRYPGRIETMFSAMQNVVPSHLCDTELFDFKGIHHGSEVVNGGDLAFDREEIPMMPAGWTPEDDAAPPMQRLDVLEIK
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CZCR_BACAN
Sequence: MELRDLQIFQSVADQGSVSSAAKELNYVQSNVTARIKQLENELKTPLFYRHKRGMTLTAEGRKMLVYVNKILQDVDELKQVFLDSETPSGILKIGTVETVSTLPTILSSYYKSYPNVDLSLQAGLTEELIREVLDHQLDGAFISGPIKHPLIEQYDVSTEKLMLVTQNKTFHIEEFTTTPLLVFNQGCGYRSKLERWLKDEGLLPKRIMEFNILETLLNSVALGLGITLVPQSAVHHLSKAGKVHCHAIPEKYGSISTVFIRRKDSYMTNSMRSFLKTIEEHHHINML
What are the official names of this protein?
HTH-type transcriptional regulator CzcR.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: P52K_HUMAN
Sequence: MPNFCAAPNCTRKSTQSDLAFFRFPRDPARCQKWVENCRRADLEDKTPDQLNKHYRLCAKHFETSMICRTSPYRTVLRDNAIPTIFDLTSHLNNPHSRHRKRIKELSEDEIRTLKQKKIDETSEQEQKHKETNNSNAQNPSEEEGEGQDEDILPLTLEEKENKEYLKSLFEILILMGKQNIPLDGHEADEIPEGLFTPDNFQALLECRINSGEEVLRKRFETTAVNTLFCSKTQQRQMLEICESCIREETLREVRDSHFFSIITDDVVDIAGEEHLPVLVRFVDESHNLREEFIGFLPYEADAEILAVKFHTMITEKWGLNMEYCRGQAYIVSSGFSSKMKVVASRLLEKYPQAIYTLCSSCALNMWLAKSVPVMGVSVALGTIEEVCSFFHRSPQLLLELDNVISVLFQNSKERGKELKEICHSQWTGRHDAFEILVELLQALVLCLDGINSDTNIRWNNYIAGRAFVLCSAVSDFDFIVTIVVLKNVLSFTRAFGKNLQGQTSDVFFAAGSLTAVLHSLNEVMENIEVYHEFWFEEATNLATKLDIQMKLPGKFRRAHQGNLESQLTSESYYKETLSVPTVEHIIQELKDIFSEQHLKALKCLSLVPSVMGQLKFNTSEEHHADMYRSDLPNPDTLSAELHCWRIKWKHRGKDIELPSTIYEALHLPDIKFFPNVYALLKVLCILPVMKVENERYENGRKRLKAYLRNTLTDQRSSNLALLNINFDIKHDLDLMVDTYIKLYTSKSELPTDNSETVENT
What is the function of this protein?
Upstream regulator of interferon-induced serine/threonine protein kinase R (PKR).  May block the PKR-inhibitory function of DNAJC3, resulting in restoration of kinase activity and suppression of cell growth.
What are the official names of this protein?
52 kDa repressor of the inhibitor of the protein kinase, p52rIPK, 58 kDa interferon-induced protein kinase-interacting protein, p58IPK-interacting protein, Death-associated protein 4, THAP domain-containing protein 0, THAP domain-containing protein 12.
Protein: RS11_CALS8
Sequence: MARPARRTVRRSERKNVEKGIAHIHSTFNNTIVTITDPSGNAIAWASAGTCGFSGTKKGTPFAAQLAAEKAAKMAMDHGMRTVEVYVKGPGAGREAAIRALQAAGLEVTLIKDVTPIPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: PAN2_CRYNJ
Sequence: MNYNPLHLLPLPPTALDPKPIPTSLTLDPFSDVLWVGASSGIVSALCSPLTLARNVHFPAHGCKIGGGGFSAQGVSAVREVRVTDRDVWTLTEGGIGGRKRGGAPKWIVSDVTRSLRTMSPNPTNSHELITGGSGSLLLANTARGEVVRSIENSSPVVKLAPLHRTVLAAGLSGQVTVLDPRTGFKAAQNISPVQAHTGGLSGADVQGNIVATWGWTHMQGHPLPDPLIRLYDVRALRPLPPISFSSGPAFVLLHPSSSSHIVVSSQQGMLQTIDMSLGPSATVFQQLDVSSYITSMALSSRGDYLAFGDGDGQLHVWTTNETGENAAVDENGSIVLPPFNGYDGVKPEWPDQVDPLPTIAWEESTPLNLVGMPYYNEALLSQFPSECYATSTSPLFNPPATIPQPVLSSMKMVDFVGYAPNPKELRGKRYVLRAVPGAEGRARGKGRRDSGPRFRSEKDKKGTYKDKEEIEEELNDGEVPKYYRKVEIKYSKFGIEDFDFEFYNRTNYSGLETDILNSYTNSLLQALHYTLPLRAIATAHICVDCKKEHCLLCEAGFLFRMLEDAKGRNCQASNFSRAFSATSQAYALGLMDENTNSKSTAPYGSLIQNFNRWLLSTFSTESIVDGETFHLRPFPQKTSGLDGLSMNDGPSAIDQVLGVKIKTTNTCRHCGFVSSRDSTLHVVDLVYPKKMNPRLSFSDILRSSLIRDSTTKAICSSCKAFAPLDSRRSLSPSSGHPLPPVLSVNAMVTNSDVYGFWKDKKDVKEKDGVRRFLPKRVTIREVGKLENGQEEGVKYSIRSMVVQIQESPDAVAHLVSFVKMPSKDGSSAWIMFNDFLVRPVSEDEVLSFPDQWKVPAVIILERENAEELLNLEVLPKELDREILFKDVSIAWNRKQDMIKHKILQREEMPKRGTLVAIDAEFVALQQEEMEFRSDGTKNILRPSHMSLARVSVLRGEGEMEGKPFIDDYIHTSEAVVDYLTEFSGIKAGDLDPNNSPHTLVPLKVAYKKLRLLVDLGCIFVGHGLSKDFRTINIFVPPEQVMDTVLIYTLPGSQRKLSLRFLAWYLLHQDIQTNSHDSIEDAHFALLLCKLWMDYASESEEAFEIVMEDIFAEGKKLAFKPPSSAGNMMAEQQLSPVSFPPLSNGDQTVARAVVKSRMATPPPPTKLGLPQWASQNSPSPLRR
What is the function of this protein?
Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover.  PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1.  PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex.  Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1.  May also be involved in post-transcriptional maturation of mRNA poly(A) tails.
What are the official names of this protein?
PAN2-PAN3 deadenylation complex catalytic subunit PAN2, PAB1P-dependent poly(A)-specific ribonuclease, Poly(A)-nuclease deadenylation complex subunit 2, PAN deadenylation complex subunit 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. PAN2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPEA_ECOLI
Sequence: MSDDMSMGLPSSAGEHGVLRSMQEVAMSSQEASKMLRTYNIAWWGNNYYDVNELGHISVCPDPDVPEARVDLAQLVKTREAQGQRLPALFCFPQILQHRLRSINAAFKRARESYGYNGDYFLVYPIKVNQHRRVIESLIHSGEPLGLEAGSKAELMAVLAHAGMTRSVIVCNGYKDREYIRLALIGEKMGHKVYLVIEKMSEIAIVLDEAERLNVVPRLGVRARLASQGSGKWQSSGGEKSKFGLAATQVLQLVETLREAGRLDSLQLLHFHLGSQMANIRDIATGVRESARFYVELHKLGVNIQCFDVGGGLGVDYEGTRSQSDCSVNYGLNEYANNIIWAIGDACEENGLPHPTVITESGRAVTAHHTVLVSNIIGVERNEYTVPTAPAEDAPRALQSMWETWQEMHEPGTRRSLREWLHDSQMDLHDIHIGYSSGIFSLQERAWAEQLYLSMCHEVQKQLDPQNRAHRPIIDELQERMADKMYVNFSLFQSMPDAWGIDQLFPVLPLEGLDQVPERRAVLLDITCDSDGAIDHYIDGDGIATTMPMPEYDPENPPMLGFFMVGAYQEILGNMHNLFGDTEAVDVFVFPDGSVEVELSDEGDTVADMLQYVQLDPKTLLTQFRDQVKKTDLDAELQQQFLEEFEAGLYGYTYLEDE
What is the function of this protein?
Catalyzes the biosynthesis of agmatine from arginine.
What are the official names of this protein?
Biosynthetic arginine decarboxylase, ADC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: HIS7_STRSV
Sequence: MRQAEIKRKTQETDIELAVNLDQQEPVAIETGVGFFDHMLTLFARHSRISLTVKAEGDLWVDSHHTVEDVGIVLGQALRQALGDKAGINRYGTSFVPMDETLGMASLDLSGRSYLVFEADFDNPKLGNFETELVEEFFQALAFNLQMNLHLKILHGKNSHHKAESLFKATGRALREAITINPEIHGVNSTKGLL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_BORDL
Sequence: MIKRVHLGQGKAEEILNLPNLIEIQLNSYEKFLQLERLKNNKPLLNEGLESVFRDVFPMKSSNGEVALEYEKYYIEYDSISFTEKECKRKGQSYEAVLKIRLNLQFLTTGEIRQKDVYMGTIPLMTDRGTFIVNGAERVIVSQIHRSPGVVFYKEKDLYYARIIPYRGSWLEFEIDSKKDYLYVKIDRKKRILVTLFLRALGLDTREKIIETFYKIRKIEVNDDTKREITGQYLATNITIKENMTYRAGDKITLQDIEDFLQNGVKEINLIDFDGYDSVPGKHFISSDVILNCFEKEDAYFALKDGFKELSRESVMLAVYSVLLPGEPISIDNAENDLRTVFFSEKRYDLGHVGRYKLSKKFGLDDLTTSVLTMTDIVNTISHLLRIYDGHDVLDDIDHLGNRRVRSVGELLTNIYKGAMSRVEKIAKDRMSNKEVFNLKPQELISVKPVVSAVKEFFATSQLSQFMDQVNPLAELTHKRRLNALGPGGLSRDRAGFEVRDVHYTHYGRMCPIETPEGPNIGLIVSLATYSKVNDYGFLETPYRKVIDGKVTDDIEYLSAIDEEKKCIAQANASVSSDGNYTDDLVSVRISGDYTTMMPKNIDYMDVSPRQLISVSSALIPFLEHNDANRALMGSNMQRQAVPLLFPQPPIVGTGMERIVAKDSGVVIKAKRPGRVVLATNKKIVIKPDNATSERDLDEYELYKYERTNQDTSFNHSVLVKNGQIVNKDEIIADGPATRYGELALGNNLLVGFIPWNGFNYEDAILISERIVKEDLYTSIHIKEFSIEVRETKLGPEKVTADIPNVSGKILSKLDENGIVRIGTYVKPGDILIGKVTPKSEGDITPEFKLLTSIFGEKAKDVKNNSLKVPHGTEGTVIDVQRITKDDVGNLPPGVDEILKVYIAKKRKLKEGDKMAGRHGNKGVVAKILPVEDMPYLADGTPLDICLNPLGVPSRMNIGQLMESQLGLAGKYLGEYYDVPVFESATNECIQEKLKKAGFNETSKAVLYDGYTGEPFENEVMVGVIYMLKLHHLVDDKMHARSTGPYSLVSQQPLGGKAQFGGQRLGEMEVWALEAYGAAHTLQELLTVKSDDMSGRVKIYENIVKGIPTNVSGIPESFNVLMQELRGLGFDLSIYDDNGNQIPLTEKEEELINKT
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: MNMA_THESQ
Sequence: MKVGVALSGGVDSAVALYLLLKEGHEVKAFHMKTKEDEFFLKKEIKKKVCCSPSDTADAIRIARSLGVEIEIVDVREVFREKVIEPFKRDLLRGLTPNPCVHCNRYVKFGYFMDYVLSQGFDAFASGHYARVEFSGKYGKKVIKKGVDGKKDQSYFLARIEPWRIEKLLFPNGIYTKEEIRRIAEEAGIHVAKKQESQDVCFIPDGSIENFLKDEGITLSEGKVITEKGEVVGHHRGYPLYTVGQRKGLKIEKFGERLYVREKIPESNVVVVSGLEDVFFSGLIAEDPVWHVEVPEEFRCVCRVRKKSEEAPAVVRVRDNEVEVRFEKKVFAVTPGQIAAFYDEDTLLGGAIIKEGIR
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANOR_ACINO
Sequence: MESWQEDLLSAFLVVKNEDELFEVVKSTASKLGFDYCAYGMQSPLSIAEPKTIMLNNYPQAWQKRYIEQRYVKVDPTVQHCMVSLQPLVWSSQNAKTQEEKDFWEEARSYGLNVGWAQSSRDFIGTRGMLTLARSTDQLSEKEQKAQYTNMYWLTQTVHSSIAKIVNDVEFSQFNLYLTNREKEALRWTAEGKTSAEIAQIIGVTERTVNFHLCNSMQKLNVNNKISAAIRAVMLGLL
What is the function of this protein?
Positively regulates the expression of anoI.  Required for biofilm formation and motility.  Probably part of a quorum-sensing system with AnoI.
What are the official names of this protein?
Transcriptional activator protein AnoR.
What is the protein family that this protein belongs to?
Belongs to the autoinducer-regulated transcriptional regulatory protein family.
Protein: Y624_RICFE
Sequence: MTADYSFLKSFAEYIIDKLEKGTEVQIILPNNFSCLELKKILTDKYKIKLPIIIPFNSLISKKTDSDYVSKIEELLIISKIITEYKDLQFNKNESLKAAEILRKLINDLIINNIDIKLIEVYNNSNYWQKIYKFLEYCFLRWQEEISLTQKQTKAIHKLKLLQEEIIRIKNKQIILVGMFKPNVFLKRFEEDLKDYIVYYNQTSKQISDGISYYEPNDIYEEAVAIAYICSRNKDKRIAIITNNNKLKRVYCNFLDRYEDLLGNDLRLTNIGELLTSIIKILCNNFDLKLLFLLLKNPLINCSATQKLEVMLSNKNRFISSPKYLLQLQFDNEDTKEYCRNLIDILFTDNPHNILDILTLTKEIAEKLLPTIWEKEGGAELVEFLTNLTAYSKYINSMDKKDFPKIFSFLLSNIKYYKNTDSANIIIAPPEDLALCTFDLIILPHFNNENWTPTAKSHPWLSKKALQILNIDYNETASTLYSDYFNLFLQNKQVIILNAKKYDGKLSVPSNLFLKLQDVIPAVHYVIPAEAGIHLDMDSRRCWNDIRKDDIGDESTAHSHSFPSVLSVTDIETLIRNPYGFYAKKILGLRKKDNIWEEPKISDFGNFIHKVLEEYSKNYDKQFINLNLLDKQNALINIGNHILYGTILPNYTKKTWQIKLTAFSKAFILFDIERRKNCKEIYFETKGELRLNIAGQDIKIIGIADRIEISKSNHITILDYKTGTIPTKKEIELGLSPQLIIESLMLLENGFNIKNENTIVNSVGLGYKARGATPIIIGETTSNDVGKPKSIDYTIAYVKITSTEPYVQTTEIALSIETLNKHKAGLIKLLEYYVTNKSFSYDLNLSKYNDYLHLSR
What are the official names of this protein?
Uncharacterized protein RF_0624.
Protein: HAK23_ORYSJ
Sequence: MDDDDSGIQEEPAPPPPPPPPPPPPPPLRRLLTATRSGGSRWVDGSEVGSSESAPWSLDGDRSLRLSVDSAASAGGASGGGGGGGPLSRASSGAFRRRFGKQPRRVDSLDVEAMSVRGAHGHSSKEISMLSTVAMAFQTLGVVYGDMGTSPLYVFSDVFSKVPIKSEVEILGALSLVMYTIALIPFAKYVFIVLKANDNGEGGTFALYSLICRYAKVSLLPNQQRVDEDISSFRLKLPTPELERALSVKESLEKNPVFKNILLFLVLMGTSMVIGDGILTPSMSVMSAVSGLQGRVPGFGTDAVVIVSILFLVLLFSVQRFGTGKVGFMFAPILALWFINLGTIGIYNLAKYDISVVRAFNPVYIYLFFQTNGIKAWSALGGCVLCITGAEAMFADLGHFSVKSIQVAFTAVVFPCLLIAYMGQAAYLMKYPFAVERIFYDSVPEILFWPVFVIATLAAMIASQAMISATFSCIKQAMALGCFPRIKIIHTSKKVMGQIYIPVMNWFLMVMCIIIVATFRSTNDIANAYGIAEVGVMMVSTALVTLVMLLIWQTNLFLVMCFPVIFGSVEFVYLTAVLSKIQEGGWLPLAFSSLFLCIMYTWNYGSVLKYQSEMRGKISLDFILDLGSTLGTVRVPGIGLVYNELVQGIPSIFGHLLVTLPAMHSTIVFVCIKYVPVPYVPFEERFLFRRIGQKDYHMFRCVARYGYKDVRKEEHGFFEQLLVETLEKFLRKESQEMALEASAMAVERDDVSVVSDIPSSPVEAGDLHVPLLSDQRLGDGTQTFITEGNTPVLPTSSISEEDPSLEYELESLREAIASGFTYLLAHGDVRARKESFFTKKFIINYFYAFLRRNCRAGTATLKVPHSNIMRVGMTYMV
What is the function of this protein?
High-affinity potassium transporter.
What are the official names of this protein?
Potassium transporter 23, OsHAK23.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72.3) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL21_BURTA
Sequence: MYAVIKTGGKQYKVAVGEKLKVEQIPADIDAEITLDQVLAVGEGESIQFGTPLVSGASVKATVVSHGRHAKVTIFKMRRRKHYQKHGGHRQNYTELRIDAINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: PETL_PHYPA
Sequence: MLTIISYFGFLFGALTLALILFIGLNKIQLI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 6, Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PetL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: FMT_ECO27
Sequence: MSESLRIIFAGTPDFAARHLDALLSSGHNVVGVFTQPDRPAGRGKKLMPSPVKVLAEEKGLPVFQPVSLRPQENQQLVADLQADVMVVVAYGLILPKAVLEMPRLGCINVHGSLLPRWRGAAPIQRSLWAGDAETGVTIMQMDVGLDTGDMLYKLSCPITAEDTSGTLYDKLAELGPQGLITTLKQLADGTAKPEVQDETLVTYAEKLSKEEARIDWSLSAAQLERCIRAFNPWPMSWLEIEGQPVKVWKASVIDTATNAAPGTILEANKQGIQVATGDGILNLLSLQPAGKKAMSAQDLLNSRREWFVPGNRLV
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: RLMN_ECOLU
Sequence: MSEQLVTPENVTTKDGKINLLDLNRQQMREFFKDLGEKPFRADQVMKWMYHYCCDNFDEMTDINKVLRGKLKEVAEIRAPEVVEEQRSSDGTIKWAIAVGDQRVETVYIPEDDRATLCVSSQVGCALECKFCSTAQQGFNRNLRVSEIIGQVWRAAKIVGAAKVTGQRPITNVVMMGMGEPLLNLNNVVPAMEIMLDDFGFGLSKRRVTLSTSGVVPALDKLGDMIDVALAISLHAPNDEIRDEIVPINKKYNIETFLAAVRCYLEKSNANQGRVTIEYVMLDHVNDGTEHAHQLAELLKDTPCKINLIPWNPFPGAPYGRSSNSRIDRFSKVLMSYGFTTIVRKTRGDDIDAACGQLAGDVIDRTKRTLRKRMQGEAIDIKAV
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TNFB_MOUSE
Sequence: MTLLGRLHLLRVLGTPPVFLLGLLLALPLGAQGLSGVRFSAARTAHPLPQKHLTHGILKPAAHLVGYPSKQNSLLWRASTDRAFLRHGFSLSNNSLLIPTSGLYFVYSQVVFSGESCSPRAIPTPIYLAHEVQLFSSQYPFHVPLLSAQKSVYPGLQGPWVRSMYQGAVFLLSKGDQLSTHTDGISHLHFSPSSVFFGAFAL
What is the function of this protein?
Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (By similarity).  In its heterotrimeric form with LTB binds to TNFRSF3/LTBR.  Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo.
What are the official names of this protein?
Lymphotoxin-alpha, LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1.
What is the protein family that this protein belongs to?
Belongs to the tumor necrosis factor family.
What are the subcellular locations of this protein?
Secreted. Membrane. Note=The homotrimer is secreted. The heterotrimer is membrane- associated.
Protein: CSC2A_HUMAN
Sequence: MTQEKMYPHLFSERCANQHQHRTAEEKKYVSEKQLIHWRCEEPSAHHNSIDIKRMKHFGSALRLRQTFHLDTADHPCVITMNPALPWKLEGSNSTSTLPLPA
What is the function of this protein?
May act as a potential tumor suppressor.
What are the official names of this protein?
Protein CASC2, isoform 3, Cancer susceptibility candidate gene 2 protein, isoform 3.
Protein: PQQD_XANOM
Sequence: MSSITRDSQPALRAGVRLQHDRTRDQWVLLAPERVVELDEIALVVAQRYDGTRSLAQIAQELAAEFDADAADIEADVIELTATLQQKRLLRL
What is the function of this protein?
Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
What are the official names of this protein?
PqqA binding protein, Coenzyme PQQ synthesis protein D, Pyrroloquinoline quinone biosynthesis protein D.
What is the protein family that this protein belongs to?
Belongs to the PqqD family.
Protein: TIM21_RAT
Sequence: MICAFLRVVRHAEKLHGSLGRQLLLPHFVLTKACLKTQPLRWGLREQKKTVQPRTVLGFTQKTFWTQGPDPRKAKEDSSKQVSINRNQREETGVSTSQKVKEAGRDVTYLIVVLFGVSITGSLLYTIFKELFSSSSPNIIYGKALGKCRTHPEVISVFGEPVKGYGEMSRRGRRQHVSFTEYANNGLKRIRVKFYIEGSEPGKQGTVHAEVEENPRSGQFDFRYIFVDVAPKRSIVVEDNRFQQS
What is the function of this protein?
Participates in the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.  Also required for assembly of mitochondrial respiratory chain complex I and complex IV as component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex.  Probably shuttles between the presequence translocase and respiratory-chain assembly intermediates in a process that promotes incorporation of early nuclear-encoded subunits into these complexes.
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit Tim21, TIM21-like protein, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the TIM21 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: CLPS_XANC8
Sequence: MPRKTSHEHDHGLVVETSKPEVAPPPRYQVLLLNDDYTPMDFVVTVLQQFFNLELERATQVMLHVHTRGRGVCGVYSREVAESKVAQVNEFSRMNQHPLLCTMEQA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.