PharMolix/UniProtQA huggingface dataset:
Protein: NANOG_PANTR
Sequence: MSVDPACPQSLPCFEASDCKESSPMPVICGPEENYPSLQMSSAEMPHTETVSPLPSSMDLLIQDSPDSSTSPKGKQPTSAENSVTKKEDKVPVKKQKTRTVFSSTQLCVLNDRFQRQKYLSLQQMQELSNILNLSYKQVKTWFQNQRMKSKRWQKNNWPKNSNGVTQKASAPTYPSLYSSYHQGCLVNPTGNLPMWSNQTWNNSTWSNQTQNIQSWSNHSWNTQTWCTQSWNNQAWNSPFYNCGEESLQSCMQFQPNSPASDLEAALEAAGEGLNVIQQTARYFSTPQTMDLFLNYSTNMQPEDM
What is the function of this protein?
Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal.  Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages.  Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes.  Acts as a transcriptional activator or repressor.  Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'.  Binds to the POU5F1/OCT4 promoter.  Able to autorepress its expression in differentiating (ES) cells: binds to its own promoter following interaction with ZNF281/ZFP281, leading to recruitment of the NuRD complex and subsequent repression of expression.  When overexpressed, promotes cells to enter into S phase and proliferation (By similarity).
What are the official names of this protein?
Homeobox protein NANOG, Homeobox transcription factor Nanog.
What is the protein family that this protein belongs to?
Belongs to the Nanog homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS5_STAA1
Sequence: MARREEETKEFEERVVTINRVAKVVKGGRRFRFTALVVVGDKNGRVGFGTGKAQEVPEAIKKAVEAAKKDLVVVPRVEGTTPHTITGRYGSGSVFMKPAAPGTGVIAGGPVRAVLELAGITDILSKSLGSNTPINMVRATIDGLQNLKNAEDVAKLRGKTVEELYN
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: TNR9_HUMAN
Sequence: MGNSCYNIVATLLLVLNFERTRSLQDPCSNCPAGTFCDNNRNQICSPCPPNSFSSAGGQRTCDICRQCKGVFRTRKECSSTSNAECDCTPGFHCLGAGCSMCEQDCKQGQELTKKGCKDCCFGTFNDQKRGICRPWTNCSLDGKSVLVNGTKERDVVCGPSPADLSPGASSVTPPAPAREPGHSPQIISFFLALTSTALLFLLFFLTLRFSVVKRGRKKLLYIFKQPFMRPVQTTQEEDGCSCRFPEEEEGGCEL
What is the function of this protein?
Receptor for TNFSF9/4-1BBL.  Possibly active during T cell activation.
What are the official names of this protein?
Tumor necrosis factor receptor superfamily member 9, 4-1BB ligand receptor, CDw137, T-cell antigen 4-1BB homolog, T-cell antigen ILA.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: CTU1_ASPNC
Sequence: MPPSPCARCHDQRAVIIRPKNRQKLCRTCFLHVFETEVHETITSTSLFHPGERVAIGASGGKDSTVLAAVLKTLNERYNYGLDLCLLSIDEGIKGYRDDSLETVKRNAQQYNMPLVIVSYGDLYGWTMDQVVAQVGKKGNCTYCGVFRRQALDRGAAKLGIKHVVTGHNADDVAETVMMNLLRGDLPRLSRGTSIVTGSAASDIKRSKPLKYAYEKEIVLYAHHRQLDYFSTECIYSPEAFRGSARTLIKDLEKIRPSSILDIVKSGEDMALLKKVKSQVLGTCERCGYISSQRVCKACTLLEGLNKNRPKTAIEMEIGLEDEESSSTLRRQMEKVELGGV
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation.  It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated urm1 onto the uridine of tRNAs at wobble position.  Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation.  May also be involved in protein urmylation.
What are the official names of this protein?
Cytoplasmic tRNA 2-thiolation protein 1, Cytoplasmic tRNA adenylyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP_NITEU
Sequence: MQPMFDRERNGLDTTGLGLIPMVIETSGRGERAYDIYSRLLRERIIFLVGPVTETSANLVIAQLLFLESENSEKDIFLYINSPGGLVTAGLAVYDTIQFIKPDVSTLCVGQAASMGAFLLTAGAKGKRYCLPNSRVMIHQPLGGFQGQASDIEIHAKEILALKSRLNEIMAKHTGQTVKAIERDTDRDNFLGAEAAVKYGLVDAVLTSREVKQE
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR5_SALPK
Sequence: MTDKTSLSYKDAGVDIDAGNALVDRIKGVVKKTRRPEVMGGLGGFGALCALPQKYREPVLVSGTDGVGTKLRLAMDLKRHDAIGIDLVAMCVNDLVVQGAEPLFFLDYYATGKLDVDTAASVINGIAEGCLQSGCALVGGETAEMPGMYHGEDYDVAGFCVGVVEKSEIIDGSRVAEGDVLIALGSSGPHSNGYSLVRKIIDVSGCDPQTTLLEGKPLADHLLEPTRIYVKSVLELIENVDVHAIAHLTGGGFWENIPRVLPENTQAVINESSWQWPAIFTWLQTAGNVSRHEMYRTFNCGVGMVIALSAPEADKALALLNEKGENAWKIGIIKASDSEQRVVIE
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_ACIC5
Sequence: MANITMKELLEAGVHFGHQTKRWDPRMKEYIFGERNGIYIIDLQKTLKMFKDASKYVTDMCAQGKVILFVGTKRQAQDAIAEEANRCGMYYINNRWLGGLLTNWVTVQKSVKRLQELDEMATDGRYDLLTKKEVIRLERERKHLQANLAGIKNMRRLPDAIFVVDSNNEAIAVKEARKLGIPVVAVVDTNCDPTVVDYVIPGNDDALRAIRLFTSKIADSVIEGVQMVGDKQFAAEMEGVNTDVQAVAEGEEAPAAEVAAPVAEAAAETEDVDLEAALGGGIRKSPAVVNALDEAEAAESL
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: ANMK_MAGSA
Sequence: MLALGLMSGTSLDGVDVALLETDGETVARFGPATTVPYGDEQRIALMGVLGGKGPVEQVERDFTLFHAQVVRDFLAAQGIDAATVGVAGFHGHTILHAPAERRTWQIGDGALLASEIGIPVVNDFRSADVAAGGQGAPLVPVYHRALAAGLEAPLAILNLGGVGNVTWISDDGSLLAFDTGPGNALLDDWALAHTGRPVDVDGRLAAAGKVRRDAVEAFLHHTYFDCQPPKSVDRDEFHALAWELVKGCSAEDGAATLTAFTAAAVALAAYSFPRPVKRWLVTGGGRRNPEMMTALSRGLSAPVEPVEAVGWNGDALEAQAFAFLAVRSLAGKMLTYPETTGAPAPQTGGRHHVP
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: HCY_SCYOL
Sequence: ADCQAGDSADKLLAQKQHDVNYLVYKLYGDIRDDHLKELGETFNPQGDLLLYHDNGASVNTLMADFKDGRLLQKKHWFSLFNTRQREEALMMHRVLMNCKNWHAFVSNAAYFRTNMNEGEYLYALYVSLIHSGLGEGVVLPPLYEVTPHMFTNSEVIHEAYKAQMTNTPSKFESHFTGSKKNPEQHVAYFGEDVGMNTHHVLWHMEFPFWWEDSSGRHLDRKGESFFWVHHQLTVRYDAERLSNHLDPVEELSWNKAIDEGFAPHTAYKYGGYFPSRPDNVHFSDVDGVARVRDMSMTEDRIRDAIAHGYIDALDGSHIDIMNSHGIEFLGDIIESSGYSANPGFYGSLHNTAHIMLGRQGDPTGKFDLPPGVLEHFETSTRDPSFFRLHKYMDNIFREHKDSLTPYTRDELEFNGVSIDSIAIEGTLETFFENFEYSLLNAVDDTVDIADVEILTYIERLNHKKFSFLILVTNNNNTEVLATVRIFAWPLRDNNGIEYSFNEGRWRALELDRFWVKVKHGHHQITRQSTESSVTVPDVPSLQTLIDRADAAISSGCALHLEDYESALGLPNRFLLPKGQAQGMEFNLVVAVTDGRTDAALDDLHENTKFIHYGYDRQYPDKRPHGYPLDRRVDDERIFEALPNFKQRTVKLYSHEGVDGG
What is the function of this protein?
Hemocyanins are copper-containing oxygen carriers occurring freely dissolved in the hemolymph of many mollusks and arthropods.
What are the official names of this protein?
Hemocyanin subunit.
What is the protein family that this protein belongs to?
Belongs to the tyrosinase family. Hemocyanin subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: HBA2_ARCGA
Sequence: MVLSPADKTNVKTTWDKLGGHAGEYGGEALERTFTAFPTTKTYFPHFDLSHGSAQVKAHGKKVADALTTAVAHMDDLPGALSALSDLHAYKLRVDPVNFKLLSHCLLVTLACHHPAEFTPAVHASLDKFFSAVSTVLTSKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-2, Alpha-2-globin, Hemoglobin alpha-2 chain, Hemoglobin alpha-II chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: ATPF_SALTY
Sequence: MNLNATILGQAIAFILFVWFCMKYVWPPLMAAIEKRQKEIADGLASAERAHKDLDLAKASATDQLKKAKAEAQVIIEQANKRRAQILDEAKTEAEQERTKIVAQAQAEIEAERKRAREELRKQVAILAVAGAEKIIERSVDEAANSDIVDKLVAEL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: FPG_THEFY
Sequence: MPELPEVEVVRRGLEKWVVGASFGEVEVLHPRAVRRHAPGAADFAARVSGCGVTEARRRGKYLWLTLDSGEALLAHLGMSGQLLVQPRHAAAERHLRVRLPLTARQGHDPEAPQELRFVDQRTFGHLLVDRLVDDGTGTGLPSVISHIARDPLDPAFDEDAFAAALCRKRTELKRALLDQSLISGIGNIYADEALWMSQLHWATPTEALSRSQVATLLAAVREVMVAALAQGGTSFDSLYVNVNGESGYFARSLNAYGRNDQPCARCGTPIQRETFMNRSSYSCPRCQPRPRHARA
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: RLMKL_FRATN
Sequence: MQKFTFFVSCAKGIELLLKDELERLGISSQEKLAGVEFEGSIKDAYKVCIYSYLASQVMLKVATDKVINQQDLYEFISSINWMDYFAVDKTFKIIISGKHYDFNNTMFVSQKTKDAIVDQFRNVTNQRPNIDTENPDNVIKLHLHKQFVNVFLCLNIDSLHKRSYRQFQGQAPLKESLAAAILIKAGWLEELKKHQPILIDPMCGSGTILIEAALMAKNIAPVLLNKEFKIFNSKFHNKELWDNLLEIAKNSQKVTNAIICGFDIDNNVLDKAQRNIYQAGVEDVVTVKRQDIRDLENEFESEGLIVTNPPYGERLYGDQLDELLDIFNGFGDRLSQDFYGWKVAVLTSFADSIKEMQLRTTKRNKFYNGAIETILYQFEINEHAKFKHETQLEKNIRIAEASVQKSDEHIDFANKLKKNLKSLKPWLKQTGLECYRLYDADIPTFAVAVDVYGEHIFLQEYRADATIDQNIAKQRFYQAIYQIHKTLDIKYENIHTRVRQRQKGKEQYQKENDKNKFHIINEFDAKFYVNFDDYLDTGIFLDHRKIRQLVAKAAKNKTLLNLFSYTCTASVHAALKGAKTTSVDMSNTYLEWGKNNFELNKLDIKKHSFIQADCISWLKTNKDKFDVIFLDPPTFSNSKRMDDILDIQRDHELLINLAMDSLKKDGILYFSNNYRRFKMSPQILEKFNCENIDKICLSRDFLSNKNIHNCWEIKYKK
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_CERSK
Sequence: MALKSYKPTTPGQRGLVLIDRSELWKGRPVKTLVEGLIKTGGRNNTGRVTMWHKGGGAKRLYRIVDFKRRKFDVPAVVERIEYDPNRTAFIALVRYEDGELAYILAPQRLAVGDSVVAGVKTDVKPGNAMPFSGMPIGTIVHNVELKPGKGGQLARAAGTYAQFVGRDGGYAQIRLSSGELRMVRQECMATVGAVSNPDNSNQNFGKAGRMRHKGVRPTVRGVAMNPIDHPHGGGEGRTSGGRHPVTPWGKGTKGNRTRKSKASDKLIVRSRHAKKKGR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: GLPK_PSEE4
Sequence: MTDNLDKNYIIALDQGTTSSRAIIFDRDANVVGTSQREFAQHYPQAGWVEHDPMEIFATQSATMVEALAQAGISHAQVAAIGITNQRETTVVWDKETGRPVYNAIVWQCRRSTEICAQLKRDGHEQYIREATGLVTDPYFSGTKLKWILDNVEGARERAERGELLFGTIDTWLIWKFSGGKVHVTDYTNASRTLMFNIHTLHWDEKLLDILGIPRQMLPEVRPSSEVYGKTKSGIDIAGIAGDQQSALFGQMCVEPGQAKNTYGTGCFLLMNTGDKAVKSSHGLLTTIACGPRGEVAYALEGAVFNGGSTVQWLRDELKIVNDAHDTEYFASKVKDSNGVYLVPAFTGLGAPYWDPYARGALFGLTRGVKVDHIIRAALESIAYQTRDVLDAMQQDCGERLSELRVDGGAVANNFLMQFQADILGTCVERPKMRETTALGAAYLAGLACGFWSGLDELRDKAIIEREFSPQLAEAEKEKLYKGWRKAVDRTRDWEDHDA
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: PNP_SALRD
Sequence: MKPEAHIEDIEFVPDRSLSLETGRIAKQADGSVVARLGDTMVLSTATLSDSVNESNFFPLTVDYREKFAAGGKVPGGFIKREGRPTDKETLTSRLIDRAIRPLFPDGFYHDVHVVNFVISAGQDFDADVIAGVGSSAALMLSGAPFAGPFAEVRVGRVDGDYIVNPTMQQTEESDIDLVVAGKEDALVMVEGEAEEISEESMIEALDVAHRSIRRLCEGQHRLVEQAGEPDPFEWEADRVPEQLVQRMREEYGPKVADHIHGPYSKETFHGGIGDLKDQAVDDVLGDASETPEGYTASDIRDAIGEVEKGEMRNMIVEEGKRIDGRDQTDVRDLWMEVGYLPRVHGSAIFTRGETQVLGSITLGTSDDVQPVDEVFADTDKSFYLHYRFPPFSVGEASYLRGPKRREIGHSMLAERALRPVIPEQDEFPYTIRINADVMESNGSSSMASVCAGSLALMDAGVPIEKPVAGIAMGLVQEDDETTVLTDILGQEDHLGDMDFKLTGTRDGITACQMDMKIEGLSRDVMLKALKQSRDARHHILDRMEETIAEPRAELSSHAPRLTKLTIDPDRIGAVIGPGGKVVKSVQEETNTEITVEEEEGVGIVTIAATNQRDAEAAIERIKQIVAVPEEGEDYVGTVKGIRDFGAFVEIMPEKTGLLHVSEIDYDYVENVEDYLEVGDKVKVHLLEVHDDGKMRLTRKPFVSEENGEQNE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2307_BACHK
Sequence: MLGINVKKTKEELIISWQLAKITIPLRDVIEVTEDATYAGVEDTSAIRIGTAYGTTDRILIKTVKQNYVLFTTNKVSILNAINA
What are the official names of this protein?
UPF0457 protein BT9727_2307.
What is the protein family that this protein belongs to?
Belongs to the UPF0457 family.
Protein: MRC2_RAT
Sequence: MGPIRPALAPWPRHLLRCVLLLGGLRLGHPADSAAALLEPDVFLIFSQGMQGCLEAQGVQVRVIPVCNASLPAQRWKWVSRNRLFNLGAMQCLGTGWPATNTTVSLGMYECDREALSLRWQCRTLGDQLSLLLGARANNASKPGTLERGDQTRSGHWNIYGSEEDLCARPYYEVYTIQGNSHGKPCTIPFKYDNQWFHGCTSTGREDGHLWCATTQDYGKDERWGFCPIKSNDCETFWDKDQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYSSTLWIGLNDLDTSGGWQWSDNSPLKYLNWESDQPDNPGEENCGVIRTESSGGWQNHDCSIALPYVCKKKPNATAEPIQPDRWANVKVECDPSWQPFQGHCYRLQAEKRSWQESKRACLRGGGDLLSIHSMTELEFITKQIKQEVEELWIGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVTIWGPEGRWNDSPCNQSLPSICKKAGRLSQGTAEEDHGCRKGWTWHSPSCYWLGEDQVIYSDARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYFWTALQDLNSTGSFRWLSGDEVMYTHWNRDQPGYRRGGCVALATGSAMGLWEVKNCTSFRARYICRQSLGTPVTPELPGPDPTPSLTGSCPQGWVSDPKLRHCYKVFSSERLQEKKSWIEALGVCRELGAQLLSLASYEEEHFVANMLNKIFGESEPENHEQHWFWIGLNRRDPREGHSWRWSDGLGFSYHNFARSQHDDDNIRGCAVLDLASLQWVAMQCQTQLDWICKIPRGVDVREPDIGRQGRLEWVRFQEAEYKFFEHHSSWAQAQRICTWFQAELTSVHSQAELDFLGQNMQKLSSDQEQHWWIGLHTSESDGRFRWSDGSVINFVSWAPGKPRPIGKDKKCVYMTARQEDWGDQRCHTALPYICKRSNSSGETRPHDLPPSTLGGCPSGWNQFLNKCFRIQGQDPQDRVKWSEAQFSCEQQEAQLVTIANPLEQAYITASLPNVTFDLWIGLHGSQRDFQWIEQEPLLYTNWAPGEPSGPSPAPSGTKPTSCAVILHSPSAHFTGRWDDRSCTEETHGFICQKGTDPSLSPSPAAALPAPGTELSYLNRTFRLLQKPLRWKDALLLCESRNASLAHVPDPYTQAFLTQAARGLQAPLWIGLASEEGSRRYSWLSEEPLNYASWQDGEPQHTGGCAYVDVDGTWRTTSCDTKLQGAVCGVSRGPPPPRISYRGSCPQGLADSSWIPFREHCYSFHTELLLGHKEALQRCQRAGGTVLSILDEMENVFVWEHLQTAETQSRGAWLGMNFNPKGGMLVWQDNTAVNYSNWGPPGLGPSMLSHNSCYWIQSSSGLWRPGACTNVTMGVVCKLPRVEENGFLPSAALPENPVALVVVLTAAVLLLLALLTGALILYRRRQSAERGSFEGARYSRSSRSGPAEATEKNILVSDMEMNEQQE
What is the function of this protein?
May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity.  Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis.  May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface.  May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices (By similarity).  May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs) secreted by hepatic stellate cells.  May mediate endocytosis of partially degraded collagens and glycoproteins produced in the extracellular matrix by MMPs.
What are the official names of this protein?
C-type mannose receptor 2, Endocytic receptor 180, Macrophage mannose receptor 2.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RL23_RHOPB
Sequence: MKTIDPRHYDVIVAPVVTEKATIASEHNKVVFKVASKATKPQIKEAVEKLFDVKVKSVNTLVRKGKTKVFRGQFGSQSDVKRAIVTLEEGHRIDVTTGL
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: ATPE_STRP1
Sequence: MTQMTVQVVTPDGIKYDHHAKFISVTTPDGEMGILPNHINLIAPLQVHEMKIRRGGEDEKVDWIAINGGIIEIKDNVVTIVADSAERDRDIDVSRAERAKLRAEREIAQAETTHNIDEVRRAKVALRRALNRINVSKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: KDSB_ALIFM
Sequence: MSFTVIIPARYQSTRLPGKPLADICGKPMIQWVYEQASKAGADRVIIATDDSRIEAVVKGFGGDVCMTSPNHESGTERLAEVIEKCGISADEIVVNVQGDEPLIPPSIIQQVAQNLSDSVAPMATLAVTIDEEDDVFNPNAVKVVTDAEGYALYFSRASIPWDRDAFAQGETLTANPLLRHIGIYAYRAGFINTYINWQPSVLEKIECLEQLRVLWYGEKIHVAVAKEAPAAGVDTPEDLEKVRAILSK
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENDUC_DANRE
Sequence: MASGYDFGWIPVLLSLFTLTDASSQTVNQELSNIFNELWKLDVNRMEPLTNYNISLQGKAGYIPQGSTNVVDHASSPLFVNVDEAKLSSITTYARFMKLLDNYERSTGVAERVTAEEVTENNSFLDAILETAVMKRAHQYLIGKGKSRSDLRQFKSQLYYMWFRLYHRERNGGEDSSGFEHVFVGETKFGREIMGLHNWVQFYLQEKQNLLDYKGYKARANDVPDADDHVLNVQFSWHGLVKPVASAFVGVSPEFEMAVFTILFLTSTEKTTTAVVNLDEYQLEMVVHRHGRCIGTAYPKLLSSNNRHM
What is the function of this protein?
Endoribonuclease that cleaves single-stranded RNAs at 5' of uridylates and releases a product with a 2',3'-cyclic phosphate at the 3'-end.  The UU and GU sites are more efficiently cleaved than CU and AU sites.
What are the official names of this protein?
Uridylate-specific endoribonuclease C, Protein endoU-C.
What is the protein family that this protein belongs to?
Belongs to the ENDOU family.
What are the subcellular locations of this protein?
Secreted.
Protein: GLNA_CRYNB
Sequence: MSQLIATKRVDLLAPYLALDQGSRVQAEYIWIDAEGGIRSKTMTLDKAPSSVADLKEWNFDGSSTNQAPADNSDVFLRPVAIFKDPFRGGANILVLCECYDNDGTPNKSNYRAHCKKVMDAAKDTEPWFGLEQEYTLFDADGQVFGWPKNGFPGPQGPYYCGVGAGKVFARDFIEAHYRACLYAGIKISGINAEVMPSQWEFQVGPCTGIEMGDHLWMARFLLLRIGEEWGITPSLHPKPLKGDWNGAGCHSNYSTKDMRTPGKGMAAIEDAIKKLEKKHLEHIAVYGEDNDLRLTGKHETASMTTFSAGVANRGASIRIPRHVGAQGYGYLEDRRPASNVDPYRVTAILVETTVLNN
What are the official names of this protein?
Glutamine synthetase, GS, Glutamate--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_MYCPN
Sequence: MAKKDQLTLRGPLYGNNRSHSKTITRRKWNVNLQPCKVKTADGKTTRILVSTRTLRTLKKHNRLS
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: TSNP_TITSE
Sequence: KLSGCFGFKLDRIGTMSGLGC
What is the function of this protein?
Scorpion venom natriuretic peptide that increases the perfusion pressure, glomerular filtration rate and urinary flow in the isolated perfused rat kidney assay.  Induces a decrease of the percentages of renal transport for sodium, potassium and chloride and an increase of the urinary cGMP concentration.  Also down-regulates the mRNA expression of natriuretic peptide receptor-A (NPR1) in the kidneys whereas it up-regulates those of NPR-B (NPR2), NPR-C (NPR3) and guanylyl cyclase C (GUCY2C) mRNAs.  May exhibit hypotensive and vasodepressor activities.
What are the official names of this protein?
Natriuretic peptide TsNP.
What is the protein family that this protein belongs to?
Belongs to the natriuretic peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSBQ_CHLRE
Sequence: MALASKVATRPAVASRRGAVVVRASGESRRAVLGGLLASAVAAVAPKAALALTPVDLFDDRSVRDRGFDLIYEARDLDLPQNVREGFTQARASLDETKKRVKESEARIDADLDVFIQKSYWTEAREQLRRQVGTLRFDLNTLASTKEKEAKKAALGLRKEFIQAVEDLDFALREKDQASAAKKLEITKAKLDSVLAAVL
What are the official names of this protein?
Oxygen-evolving enhancer protein 3, chloroplastic, OEE3.
What is the protein family that this protein belongs to?
Belongs to the psbQ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane. Note=Associated with the photosystem II complex.
Protein: CR33_RANCA
Sequence: GLWEKIKEKANELVSGIVEGVK
What is the function of this protein?
Antibacterial peptide, that adopts an alpha helical conformation which can disrupt bacterial membranes.  Each caerin displays a different antimicrobial specificity.
What are the official names of this protein?
Caerin-3.3.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Caerin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PGK_STRZJ
Sequence: MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTIKYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEAAINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHASNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEKADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAFAGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAGTIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGLAALTEK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSME1_HUMAN
Sequence: MTHSSQDTGSCGIQEDGKLYVVDSINDLNKLNLCPAGSQHLFPLEDKIPVLGTNSGNGSRSLFFVGLLIVLIVSLALVFFVIFLIVQTGNKMDDVSRRLTAEGKDIDDLKRINNMIVKRLNQLNQLDSEQN
What are the official names of this protein?
Leucine-rich single-pass membrane protein 1.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: BR1C_RANDY
Sequence: FLPLLLAGLPKLLCLFFKKC
What is the function of this protein?
Antimicrobial peptide.  Has low activity against the Gram-positive bacterium S. aureus and the Gram-negative bacterium E. coli (MIC<15 uM).  Has a strong hemolytic activity.
What are the official names of this protein?
Brevinin-1DYc.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.