PharMolix/UniProtQA huggingface dataset:
Protein: PSAB_SYNSC
Sequence: MATKFPSFSQGLAQDPTTRRIWYGIATAHDFESHDGMTEERLYQKLFSTHFGHLAIIGLWVSGNLFHIAWQGNFEQWVADPLHVRPIAHAIWDPHFGQGAIDAFTQAGASSPVNIAYSGLYHWFYTIGMKTNAELYQGSIFMMILSAWALFAGWLHLQPKFRPSLAWFKNAESRLNHHLAVLFGFSSIAWTGHLVHVAIPEARGQHVGWDNFLNVLPHPAGLGPFFTGNWGVYAENPDSLNQVFGSSEGAGTAILTFLGGFHPQTEALWLTDIAHHHLAIGCIFVIAGHMYRTNFGIGHSIKEILETHNPPKGTPGDLGAGHKGLYDTINNSLHFQLGLALASLGVVTSLVAQHMYSMPSYAFIAKDYTTQAALYTHHQYIAIALMCGAFAHGAIFFIRDYDPEANKDNVLARMLEHKEAIISHLSWVSLFLGFHTLGLYVHNDVVVAFGTPEKQILVEPVFAQFVQAASGKAMYGMDVLLSNASSSASLAAQNIPGEHYWLDAINGNTDVFLPIGPGDFLVHHAIALGLHTTTLILVKGALDARGSKLMPDKKDFGYSFPCDGPGRGGTCDISAWDAFYLAVFWALNTVGWLTFYWHWKHLAIWSGNVAQFNESSTYLMGWFRDYLWLNSSQLINGYNPFGSNNLAVWAWMFLFGHLVWATGFMFLISWRGYWQELIETIVWAHQRSPIANMMGYRDKPVALSIVQARVVGLAHFTVGYVLTYAAFLIASTSGKFG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: CTL2_ARATH
Sequence: MVSKPLFSLLLLTVALVVFQTGTLVNAEDSEPSSSTRKPLVKIVKGKKLCDKGWECKGWSEYCCNHTISDFFETYQFENLFSKRNSPVAHAVGFWDYRSFITAAAEYQPLGFGTAGEKLQGMKEVAAFLGHVGSKTSCGYGVATGGPLAWGLCYNKEMSPDQLYCDDYYKLTYPCTPGVSYHGRGALPVYWNYNYGQTGEALKVDLLSHPEYLENNATLAFQAAIWRWMTPPKKHLPSAHDVFVGKWKPTKNDTAAKRTPGFGATINVLYGDQICNSGFDNDEMNNIVSHYLYYLDLIGVGREEAGPHEKLSCADQEPFSSSSSAPPSSGSSS
What is the function of this protein?
No chitinase activity (By similarity).  Required for proper cell wall biosynthesis in etiolated seedlings.  Prevents lignin accumulation in hypocotyls.
What are the official names of this protein?
Chitinase-like protein 2, AtCTL2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 19 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SRG2C_HUMAN
Sequence: MTSPAKFKKDKEIIAEYDTQVKEIRAQLTEQMKCLDQQCELRVQLLQDLQDFFRKKAEIEMDYSRNLEKLAEHFLAKTRSTKDQQFKKDQNVLSPVNCWNLLLNQVKWESRDHTTLSDIYLNNIIPRFVQVSEDSGRLFKKSKEVGQQLQDDLMKVLNELYSVMKTYHMYNADSISAQSKLKEAEKQEEKQIGKSVKQEDRQTPCSPDSTANVRIEEKHVRRSSVKKIEKMKEKHQAKYTENKLKAIKAQNEYLLALEATNASVFKYYIHDLSDLIDQCCDLGYHASLNRALRTFLSAELNLEQSKHEGLDAIENAVENLDATSDKQRLMEMYNNVFCPPMKFEFQPHMGDMASQLCAQQPVQSELVQRCQQLQSRLSTLKIENEEVKKTMEATLQTIQDIVTVEDFDVSDCFQYSNSMESVKSTVSETFMSKPSIAKRRANQQETEQFYFTVRECYGF
What is the function of this protein?
Human-specific protein that acts as a key modifier of cortical connectivity in the human brain (PubMed:22559944, PubMed:27373832, PubMed:34707291).  Acts by inhibiting the functions of ancestral paralog SRGAP2/SRGAP2A, a postsynaptic protein that regulates excitatory and inhibitory synapse maturation and density in cortical pyramidal neurons (PubMed:22559944, PubMed:27373832).  SRGAP2C is unstable but is able to heterodimerize with SRGAP2/SRGAP2A, thereby reducing SRGAP2/SRGAP2A levels through proteasome-dependent degradation (PubMed:27373832, PubMed:28333212, PubMed:31822692).  Inhibition of SRGAP2/SRGAP2A by SRGAP2C leads to an increase in synaptic density and protracted synaptic maturation of both excitatory and inhibitory synapses (PubMed:27373832, PubMed:34707291).  Modifies cortical circuit connectivity by increasing the number of local and long-range cortical inputs received by layer 2/3 pyramidal neurons (PubMed:34707291).  Also able to increase the probability of sensory-evoked responses by layer 2/3 pyramidal neurons (PubMed:34707291).
What are the official names of this protein?
SLIT-ROBO Rho GTPase-activating protein 2C, SLIT-ROBO Rho GTPase activating protein 2 pseudogene 1.
Protein: PXPA_SALCH
Sequence: MNIDLNADVGEGCASDSELLTLVSSANIACGFHAGDAQTMLTCVREALKNGVAIGAHPSFPDRDNFGRTAMVLPPETVYAQTLYQIGALGAIVQAQGGVMRHVKPHGMLYNQAAKDPHLAQAIAKAVHDYDPSLILVGLAGSELIRAGERHRLVTRQEVFADRGYQADGSLVPRMQPGALIHDEEQALAQTLDMVQAGRVKSVTGVWTTVTAQTVCIHGDGEYALAFARRLRAAFNARNIHVIA
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: TYSY_BRUMB
Sequence: MRTYLDLLQHVLDHGVDRDDRTGTGTRSVFGYQMRFDLEEGFPVLTTKKLHLRSIIHELLWFLKGDTNIAYLKENGVTIWDEWADENGDLGPVYGYQWRSWPAPDGRHIDQIANLLKMLHTNPQSRRLIVSAWNPALVDEMALPPCHCLFQFYVANGRLSCQLYQRSADIFLGVPFNIASYALLTMMIAQVTGLKPGEFIHTLGDAHIYSNHFEQARLQLTRTPKKLPVMHINPDVKDLFAFRFEDFRLDGYEADPTIKAPIAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPF_PHOV8
Sequence: MKIRVGFGFDVHQLVTGRELWLGGIKFEHELGLLGHSDADVLIHAICDALLGAANMRDIGYHFPDTAGEFKNIDSKILLAETVDLIAAKGYKVGNVDATICAERPKLKARIPEMQLVLAHLMRIDVDDVSVKATTTEKLGFTGREEGISAYATVLIEKAE
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: LPMG_ECOUT
Sequence: MEPDPTPLPRRRLKLFR
What is the function of this protein?
Makes mgtA transcription sensitive to intracellular proline levels.  Under low levels of proline this protein cannot be fully translated, and a stem loop forms which permits transcription of the downstream mgtA gene (By similarity).
What are the official names of this protein?
mgtA leader peptide, Regulatory leader peptide for mgtA.
What is the protein family that this protein belongs to?
Belongs to the MgtL family.
Protein: RL6_RICM5
Sequence: MSRVGKLPITIPEGVKIGLNDLEVKISGPKGELSKTFKGNIAISLVENKLLVKPLAANKNARAMWGTARSIISNMVTGVKEGFKLKLEINGVGYRAMVKGKYLNLMLAKSHNTKIEIPSDIKIEMPKQNIIILEGTDKEKLGQFASIIIKQRPPEPYKGKGIKFENQFIPRKEGKKN
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: ERA_DEIDV
Sequence: MSDPSMTSDGATTHSGFVAIVGKPNVGKSTLLNSFLGTKVAPTSPRPQTTRRGVRGISTTDTHQIVFVDTPGLHKPKDALGKYMNHEVHSALADVDVIIWVVDLRHPPTDEDELVARQVRELPKPLFLVGNKTDAAKYPDEAMKLYRAQLEGRSAETSEIMLSAQNNPLQVATLREQILDILPENPFFYPRGAASDQSRETWAAEIIREEAMKKLREELPYAVATRVNRWTEREDGLQRIEGEIVVEKNAHKGMVIGSGGKQLREIGQAARKQLEVFLDRKVFLGLEVIVIPGWREDEEALRELGYE
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: Y1127_HAEIN
Sequence: MLHAKVVYDSSLHFLGFIGGIFAILGVIVLPITSGDTAFRAARLQIAEIFNVDQRSLPKRLLIAVPLFVLGYFISTIDFSVLWRYFTWANQMTAMVMLWTAAGYLYRYHKFHWVASLPAWFITTVCALICSTTKLVSA
What are the official names of this protein?
Uncharacterized protein HI_1127.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PFDA_METM6
Sequence: MNEELQNQFMALDVYNQQVQKLQEELSNIDMMIMELLRSIESMEGLKSSKEILLPLGAGAFIKAEAQNPEKIILSVGVDVLLEKDVDEVIVDFQKSVKELEETKELVNTQIQKTNQEIVKLRSELEKRAAAIEQRNAQMRPKTN
What is the function of this protein?
Molecular chaperone capable of stabilizing a range of proteins.  Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
What are the official names of this protein?
Prefoldin subunit alpha, GimC subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the prefoldin alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RH8_ARATH
Sequence: MNNRGRYPPGIGAGRGAFNPNPNYQSRSGYQQHPPPQYVQRGNYAQNHQQQFQQAPSQPHQYQQQQQQQQQWLRRGQIPGGNSNGDAVVEVEKTVQSEVIDPNSEDWKARLKLPAPDTRYRTEDVTATKGNEFEDYFLKRELLMGIYEKGFERPSPIQEESIPIALTGRDILARAKNGTGKTAAFCIPVLEKIDQDNNVIQAVIIVPTRELALQTSQVCKELGKHLKIQVMVTTGGTSLKDDIMRLYQPVHLLVGTPGRILDLTKKGVCVLKDCSVLVMDEADKLLSQEFQPSVEHLISFLPESRQILMFSATFPVTVKDFKDRFLTNPYVINLMDELTLKGITQFYAFVEERQKIHCLNTLFSKLQINQSIIFCNSVNRVELLAKKITELGYSCFYIHAKMLQDHRNRVFHDFRNGACRNLVCTDLFTRGIDIQAVNVVINFDFPKNAETYLHRVGRSGRFGHLGLAVNLITYEDRFNLYRIEQELGTEIKQIPPHIDQAIYCQ
What is the function of this protein?
ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping.
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase 8.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Note=Is concentrated in several cytoplasmic foci called P bodies (or cytoplasmic processing bodies) which represent sites of mRNA decapping and 5' to 3' exonucleotidic decay.
Protein: CYSI_BLOFL
Sequence: MIMLKYNNKLLSDNERIKKNSNFLRGTIEKDLDNNLTGGFNVDNAQLIRFHGMYQQDDRDVRLERMNQKLEPLINMMLRCRLPGGVITSQQWLNIDNFSEEQTLYSSIRLTTRQTFQLHGILKPKLKGIHQLLNKLGLDSIATAGDVNRNVICTANPMESKVHYQIWELSKKISEHLLPKSKAYAEIWLNEKKIESIDSEPILSSVYLPRKFKIAIAVPPVNDVDVYANDLGLVAIKDNTGNLIGFNVLIGGGLAMTYGDKSTYPRMASEFGYINLQDILKIVESVITVQRDWGDRYNRRHAKTKYTLVKVGIDILKKEIENRSGLKFSPMYPYKFTERGDKFGWIRGINQDYWHLTLFIENGRVCNTSNILIKKGLSEIAKVHSGFFRITTNQNLIISEIHQDKKDIIEDLLKQYGLLGDFVTSQRKSSMACVAFPTCPLAMAEAERFLPAFVTKVEHVMSKYNLQRDAIILRVTGCPNGCARAMLAEIGLTGRGIGRYNLYLGGNKNGTRIPRLYKENITEDEILHVLDITIGDWAKNRKTQESYGDYVVRAGIVRAVINSEEDFYL
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: AQP3_BOVIN
Sequence: MGRQKELVNRCGEMLHIRYRLLRQALAECLGTLILVMFGCGSVAQVVLSRGTHGGFLTINLAFGFAVTLGILIAGQVSGAHLNPAVTFAMCFLAREPWIKLPVYTLAQTLGAFLGAGIIFGLYYDAIWAFANNQLIVSGPNGTAGIFATYPSGHLDMVNGFFDQFIGTASLIVCVLAIVDPYNNPVPRGLEAFTVGLVVLVIGTSMGFNSGYAVNPARDFGPRLFTAIAGWGSEVFTTGRHWWWVPIVSPLLGSIAGVFVYQLMIGCHLEPPPPSTDEENVKLSHVKHKEQM
What is the function of this protein?
Water channel required to promote glycerol permeability and water transport across cell membranes.  Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content.  Involved in skin hydration, wound healing, and tumorigenesis.  Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.  Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct cells.  It may play an important role in gastrointestinal tract water transport and in glycerol metabolism.
What are the official names of this protein?
Aquaporin-3, AQP-3, Aquaglyceroporin-3.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein.
Protein: YMPB_CAEEL
Sequence: MSISRRSYEQFDEMKSENQENNSKKKSSERLKKLDPDKFVEAYGAYGKYQIFTYVLVQTLNFFYSSSMYIMSFVQLNLEKQCEYKNETIPISETCQIETESSKAFGNLNGEYCGIAENTLVNVTNQKASTNLLVDFDLSCSHWFFQEFGLTIFTIGAVIAVPFMSMLADRYGRKPIIVTTAILAFLANMAASFSPNFAIFLILRAFIGACSDSYLSVASVATCEYLSEKARAWITVVYNVAWSLGMVWTLLVTLMTDDWRWRYFIVSLPGVYGFALWYFLPESPHWLITKNKTEKLKKYIKTANRVNNVSPEFNDCQQSSHHEEKHESFKALLGSKKLIWLLFANGFIEMVISLVYFAISFMSVELGGDQVQAFLYSSLIEIPAGLAVIPLMMKMGRKMIVIWCLVFQTLALIGVTVFLDSYEFKLVIMLVAKVMATIIYSVHPIWATEQFPTSVRSLCFSLMNIPQSMGIIMSPYVKHIVMSPNWIPFVVIALFSFISATLAFMLHETKNKKLPTDIESLSYPSETNDLSAYRRSKSSSSSVSALSKTSVRSKKTLSSESVSKKLDTVNFSDKEYRI
What are the official names of this protein?
Putative transporter B0361.11.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ATPF1_XANP2
Sequence: MNEMSLAELWVAVAFLLFVGILIYVGAHRAIGSALDSRGQRIAAELEEARRLKEEAQKLVAEFKRKQREAEAEAESIVTAAKAEAERLASEAKAKLEDFVTRRTKMAEDKIAQAELQAVADVKAIAADAAAKAAEVLLGSAARGDVGDRLISNAIGEVKTKLN
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b 1, ATP synthase F(0) sector subunit b 1, ATPase subunit I 1, F-type ATPase subunit b 1, F-ATPase subunit b 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: EIF3F_ASPFU
Sequence: MAETDSFLHLARPLGPVAVGSAPTTAPLNVVIQPQAIFSILDHSLRRNADQERVIGTLLGTRSEDGTEVEIRSTFAVGHTETTDQVEVDMEYQKQMLALHLKANPKEVLVGWYATSSELNTFSALIQNFYSGQGDGTWPHPAVHLTVSTEPGKDIETRAYISAPVGVTAERAADSAAFIPVPYEIRYGEAEKSGLEAIASAKDAESRATNIFTDIEALERAIEEVLGMIDRVSRYVESVIDEEAPASTALGQFLLNALALAPKVEPADIERDFNNHIQDVLVVSYLANTIRTQMELSNRLATAQLTLGGEGASAEAGAQRGQRGGKGGRGGQQRTQERASEEVRA
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit F, eIF3f.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit F family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VERK_CLORO
Sequence: MTNTERSSSWKASSIPDQPMWYFGYGSNMKASSMADRKVTPLSTKIVTVPTHFVTFDIFGIPYSEPSYASLEQFPDGGTGKLDLVHHISRTQVLPACGVAHLLSPNDFHRLLVTEGSGVVYNLVEVQAYEMNKDGQPIPAPFTVHTLKAKWPQRPNGTPSARYMVRFLGLLSSSTYYQY
What is the function of this protein?
Gamma-glutamyl cyclotransferase; part of the gene cluster that mediates the biosynthesis of 11'-deoxyverticillin A, one of the dimeric epipolythiodioxopiperazines (ETPs) from the verticillin family that act as mycotoxins (PubMed:28376389).  11'-deoxyverticillin A is required for normal conidiation (PubMed:28376389).  The nonribosomal peptide synthetase verP is speculated to be responsible for condensation of amino acids to form the carbon skeleton of verticillin, whereas the cluster-specific tailoring enzymes are involved in further modifications leading to the production of 11'-deoxyverticillin A (Probable).
What are the official names of this protein?
Gamma-glutamyl cyclotransferase verK, GGCT verK, Verticillin biosynthesis cluster protein K.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
Protein: FCA_ORYSJ
Sequence: MHRGGDRSTDPSSGPAPGSRGGGDGRFGRGPSRWSSGGGGGGSGSPPHRFSRGGGGGGGDGGGGGGGGGRFHPYRGPSDHSGGGGYRSGGGGEYGEPGSGPRHRYGSGRGDHSDHDNRNNYVKLFIGSVPRTATEDDVRPLFEEHGDVVEVALIKDRKTGEQQGCCFVKYATSEEAERAIRALHNQYTLPGAMGPIQVRYADGERERHGAIEHKLFVASLNKQATAKEIEEIFAPYGHVEDVYIMKDGMRQSRGCGFVKFSSREPALAAMSALSGNYVMRGCEQPLIIRFADPKRPRPGESRGGPAFGGPGFSPRSDAALVIRPTANLDEPRGRHMPPDSWHPSSPRSAPHQFNNFGSDNPMAPKGSTVTSTTDTATFRPQMFSGNGSLSSQTAVPSSSHMGMNPPPMAQGHHLGGQQIPPLQKLPGLPQNFPVQLQNNQLGQPLQGPAQQIGQLQVPQSMGPGSFGQNRLSGQLPVSQPLMQQNASVSAVQVPSAVSNSMQAIPGQQHLPSNVAPQMLQQPVQQMPSQAPQLLLQQQAALQSSYQSSQQAIYQLQQQLQLMQQQQQSNLNHQQPTQGQPVQSSNPGAPNAIIPSNINTIPQQATSPAVPLTCNWTEHTSPEGFKYYYNSITRESKWDKPEEYVLYEQQQQQQQQQKLLLLQQHQQKLAMQQLQSPPQAQTHPAMQPVQQIPQAQQGQQQMQMKQQELNYTQLQTPGAIDPSRIQQGIQSAQERAWKS
What is the function of this protein?
Plays a major role in the promotion of the transition of the vegetative meristem to reproductive development (PubMed:16240176).  Required for RNA-mediated chromatin silencing of a range of loci in the genome.  Cotranscriptionally recognizes aberrant RNA and marks it for silencing.  Controls alternative cleavage and polyadenylation on pre-mRNAs and antisense RNAs (By similarity).  Regulates flowering time, seed size and cell volume, probably via the modulation of cell size (PubMed:17597396).
What are the official names of this protein?
Flowering time control protein FCA, OsFCA, rFCA.
What are the subcellular locations of this protein?
Nucleus.
Protein: RN216_MOUSE
Sequence: MAEGNNKEEVIHLNNFPCHRGKEWMAVREGPITISDSSDEEGIPMLVTPATEQQEDDLDDDVILTEDDSEDEYGGFLDLESGKKEGEAKPGPSSKQTADDIVNPRLEQKVIILGENGLLFPESEPLEVQNQSSEDSETELLSNPGEPAASVDDQLIGEEYWLDHPYFQAPNPQPQERTNQVVPQERHSESEMGPMFFRHDFPEPAFPRPEPQQEGIPGPASPQPAHPLGELEDQQLAIDEDPGPAFPLSGPQEANLANMWEQEAAEVDQDLIPLLVKETEARFPDVASGYVEEIIHLKNYYDLNVLCNFLLENPDYPKREDRLIIHPSSSLLASQDDAKLPKIDFFDYSKLTPLDQRCFIQAADLLMADFKMLSSQDIKWALHELKGHYAITRKAFSDAIKKWQELSPETSGKRKKRKEMNQYSFIDFKFEQGNIKIEKRMFFLENKRRHCRYYDHQALLPAVKQEQEFYEQKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEFPFEELTQCADAHLFCKECLIRYAQEAVFGSGKSELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKAEEEVAAAYADELVRCPSCSFPALLDSDVKRFSCPNPRCRKETCRKCQGLWKEHNGLTCEELAEKDDIKYRTSIEEKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRVSINGYDHFCQHPRSPGAPCQECSRCSLWTDPTEDDEKLIEEIQKEAEEEQKRKNGENTFKRIGPPLEKPAEKVQRVEALPRPVPQNLHPQMPPYAFVHPPFPLPPVRPVFNNFPINMGPVPAPYVPPLPNVRVNYDFGHMHVPLEHNLPMHFGPQPRHRF
What is the function of this protein?
Acts as an E3 ubiquitin ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome.  Promotes degradation of TRAF3, TLR4 and TLR9.  Contributes to the regulation of antiviral responses.  Down-regulates activation of NF-kappa-B, IRF3 activation and IFNB production.  Promotes TNF and RIP mediated apoptosis.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF216, RING finger protein 216, RING-type E3 ubiquitin transferase RNF216, Triad domain-containing protein 3, UbcM4-interacting protein 83, Ubiquitin-conjugating enzyme 7-interacting protein 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOZ_CAMJ8
Sequence: MDKRIEEVAAKALEKMGNDRYRLSLVVAKRAEQLANGATPLVDFDKNKNKLADIALYEIAENKITLEGLVETNR
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: RNF1_GIBBA
Sequence: EASTCGSTPYSASQVRAAANAACQYYQSDDTAGSTTYPHTYNNYEGFDFAVNGPYQEFPIRTGGVYSGGSPGADRVIINTSCQYAGAITHTGASGNNFVGCSNST
What are the official names of this protein?
Extracellular guanyl-specific ribonuclease Fl1, RNase Fl1.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease N1/T1 family.
Protein: LACC_STRPS
Sequence: MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTRVLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVLEKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVVLDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWIIVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKANVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV
What are the official names of this protein?
Tagatose-6-phosphate kinase, Phosphotagatokinase.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
Protein: RS17_CLOB8
Sequence: MERSLRKKRIGRVVSDKMEKTIVVAVETKVRHPLYGKTVNRTTKFKVHDENNEAKINDRVSIMETRPLSKDKRWRLVEIVEKAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: BETI_YERPB
Sequence: MPKVGMQPIRRQQLIEATMAAVNEVGMHEASIAQIAKRAGVSNGIISHYFRDKNGLLEATMRYLIRHLGEAVKQHLAALSVNDPRARLRAIAEGNFDDSQINSAAMKTWLAFWASSMHSPQLYRLQQVNNRRLYSNLCAEFKRCLPREQAQLAAKGMAGLIDGLWLRSALSGEHFNRQEALLIIHNYIEQQLNIKYKC
What is the function of this protein?
Repressor involved in the biosynthesis of the osmoprotectant glycine betaine.  It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator BetI.
Protein: DUS_AZOBR
Sequence: MAIQIGTISLEGPVILAPMSGVTDLPFRRLVKQSGCGLVVSEMVASQAMIRENRQTLRMVECEPEQFPMAVQLAGCEPDVMAEAAKLNEDRGAAIIDINFGCPVKKVVNGHAGSSLMRDEALAARILEATAKAVTIPVTLKMRKGWDDSSLNAPRLARIAEECGIKLVTVHGRTREQFYNGTADWSFIRSVKEAVSIPVVVNGDITSFDAVDRALAESGADGVMIGRGAYGRPWFPAQVMHYIRTGERLPDPPLHEQLDTLLEHYDAMLTHYGVEGGLRVARKHISWYSTGLRDSAEFRSEVNRMSDPERVRGFIRDFYAPAIERMAA
What is the function of this protein?
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.
What are the official names of this protein?
Probable tRNA-dihydrouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the Dus family.
Protein: RL27_CAMJE
Sequence: MAHKKGQGSTQNNRDSIGRRLGVKKFGGEFVRAGNIIIRQRGTATHAGNNVGMGKDHTIFALIDGFVKFERKDKDRKKVSVYPA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: ALR_MYCAV
Sequence: MAVTPISLTPGVLAEALVDLGAIEHNVRLLCEQARGAQVMAVVKADGYGHGAVQTARAALAAGAAELGVATVDEALALRAAGISAPVLAWLHPPGIDFRPALLAGVQIGLSSQRQLDELLTAVRDTGRTATVTVKVDTGLNRNGVPPAQYPSMLTALRRAVAEQAIVPRGLMSHMVYADQPANPVNDVQAQRFTDMLAQAREQGVRFEVAHLSNSSATMSRPDLAFDMVRPGIAVYGLSPVPELGDMGLVPAMTVKCTVALVKSIRAGESVSYGHTWTAQRDTNLALLPVGYADGIFRSLGGRLQVSINGRRRPGVGRICMDQFVVDLGPGRPDVAEGDEAILFGPGSNGEPTAQDWADLLGTIHYEVVTSPRGRITRTYREAHTVES
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.