PharMolix/UniProtQA huggingface dataset:
Protein: KIF7_HUMAN
Sequence: MGLEAQRLPGAEEAPVRVALRVRPLLPKELLHGHQSCLQVEPGLGRVTLGRDRHFGFHVVLAEDAGQEAVYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEASVASLLEDEQGIVPRAMAEAFKLIDENDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLREDERGNVVLCGVKEVDVEGLDEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQRGRAPSRLPRPAPGQLLVSKFHFVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVISALGDPQRRGSHIPYRDSKITRILKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQNIRNRATVNWRPEAERPPEETASGARGPPRHRSETRIIHRGRRAPGPATASAAAAMRLGAECARYRACTDAAYSLLRELQAEPGLPGAAARKVRDWLCAVEGERSALSSASGPDSGIESASVEDQAAQGAGGRKEDEGAQQLLTLQNQVARLEEENRDFLAALEDAMEQYKLQSDRLREQQEEMVELRLRLELVRPGWGGPRLLNGLPPGSFVPRPHTAPLGGAHAHVLGMVPPACLPGDEVGSEQRGEQVTNGREAGAELLTEVNRLGSGSSAASEEEEEEEEPPRRTLHLRRNRISNCSQRAGARPGSLPERKGPELCLEELDAAIPGSRAVGGSKARVQARQVPPATASEWRLAQAQQKIRELAINIRMKEELIGELVRTGKAAQALNRQHSQRIRELEQEAEQVRAELSEGQRQLRELEGKELQDAGERSRLQEFRRRVAAAQSQVQVLKEKKQATERLVSLSAQSEKRLQELERNVQLMRQQQGQLQRRLREETEQKRRLEAEMSKRQHRVKELELKHEQQQKILKIKTEEIAAFQRKRRSGSNGSVVSLEQQQKIEEQKKWLDQEMEKVLQQRRALEELGEELHKREAILAKKEALMQEKTGLESKRLRSSQALNEDIVRVSSRLEHLEKELSEKSGQLRQGSAQSQQQIRGEIDSLRQEKDSLLKQRLEIDGKLRQGSLLSPEEERTLFQLDEAIEALDAAIEYKNEAITCRQRVLRASASLLSQCEMNLMAKLSYLSSSETRALLCKYFDKVVTLREEQHQQQIAFSELEMQLEEQQRLVYWLEVALERQRLEMDRQLTLQQKEHEQNMQLLLQQSRDHLGEGLADSRRQYEARIQALEKELGRYMWINQELKQKLGGVNAVGHSRGGEKRSLCSEGRQAPGNEDELHLAPELLWLSPLTEGAPRTREETRDLVHAPLPLTWKRSSLCGEEQGSPEELRQREAAEPLVGRVLPVGEAGLPWNFGPLSKPRRELRRASPGMIDVRKNPL
What is the function of this protein?
Essential for hedgehog signaling regulation: acts as both a negative and positive regulator of sonic hedgehog (Shh) and Indian hedgehog (Ihh) pathways, acting downstream of SMO, through both SUFU-dependent and -independent mechanisms (PubMed:21633164).  Involved in the regulation of microtubular dynamics.  Required for proper organization of the ciliary tip and control of ciliary localization of SUFU-GLI2 complexes (By similarity).  Required for localization of GLI3 to cilia in response to Shh.  Negatively regulates Shh signaling by preventing inappropriate activation of the transcriptional activator GLI2 in the absence of ligand.  Positively regulates Shh signaling by preventing the processing of the transcription factor GLI3 into its repressor form.  In keratinocytes, promotes the dissociation of SUFU-GLI2 complexes, GLI2 nuclear translocation and Shh signaling activation (By similarity).  Involved in the regulation of epidermal differentiation and chondrocyte development (By similarity).
What are the official names of this protein?
Kinesin-like protein KIF7.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIF27 subfamily.
What are the subcellular locations of this protein?
Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Note=Localizes to the cilium tip.
Protein: PTH_ECOUT
Sequence: MTIKLIVGLANPGAEYAATRHNAGAWFVDLLAERLRAPLREEAKFFGYTSRVTLGGEDVRLLVPTTFMNLSGKAVAAMASFFRINPDEILVAHDELDLPPGVAKFKLGGGHGGHNGLKDIISKLGNNPNFHRLRIGIGHPGDKNKVVGFVLGKPPVSEQKLIDEAIDEAARCTEMWFTDGLTKATNRLHAFKAQ
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CFA69_HUMAN
Sequence: MWTEEAGATAEAQESGIRNKSSSSSQIPVVGVVTEDDEAQDVFKPMDLNRVIKLLEETDKDGLEEKQLKFVKKLVQCYQNGLPLRDLAQIFKILNLCSGKIKNQPRFIESAYDIIKLCGLPFLKKKVSDEITYAEDTANSIALLGDLMKIPSSELRIQICKCIVDFYHAEPPKKHIPGYQQASSSYKIQMAEVGGLAKTMVQSMTLLENQLVEKLWVLKVLQHLSTSEVNCTIMMKAQAASGICTHLNDPDPSGQLLFRSSEILWNLLEKSSKEEVIQQLSNLECLLALKEVFKNLFMRGFSHYDRQLRNDILVITTIIAQNPEAPMIECGFTKDLILFATFNEVKSQNLLVKGLKLSNSYEDFELKKLLFNVIVILCKDLPTVQLLIDGKVILALFTYVKKPEKQKIIDWSAAQHEELQLHAIATLSSVAPLLIEEYMSCQGNARVLAFLEWCESEDPFFSHGNSFHGTGGRGNKFAQMRYSLRLLRAVVYLEDETVNKDLCEKGTIQQMIGIFKNIISKPNEKEEAIVLEIQSDILLILSGLCENHIQRKEIFGTEGVDIVLHVMKTDPRKLQSGLGYNVLLFSTLDSIWCCILGCYPSEDYFLEKEGIFLLLDLLALNQKKFCNLILGIMVEFCDNPKTAAHVNAWQGKKDQTAASLLIKLWRKEEKELGVKRDKNGKIIDTKKPLFTSFQEEQKIIPLPANCPSIAVMDVSENIRAKIYAILGKLDFENLPGLSAEDFVTLCIIHRYLDFKIGEIWNEIYEEIKLEKLRPVTTDKKALEAITTASENIGKMVASLQSDIIESQACQDMQNEQKVYAKIQATHKQRELANKSWEDFLARTSNAKTLKKAKSLQEKAIEASRYHKRPQNAIFHQTHIKGLNTTVPSGGVVTVESTPARLVGGPLVDTDIALKKLPIRGGALQRVKAVKIVDAPKKSIPT
What is the function of this protein?
Cilium- and flagellum-associated protein (PubMed:29606301).  In the olfactory epithelium, regulates the speed of activation and termination of the odor response and thus contributes to the robustness of olfactory transduction pathways (By similarity).  Required for sperm flagellum assembly and stability (PubMed:29606301).
What are the official names of this protein?
Cilia- and flagella-associated protein 69.
What are the subcellular locations of this protein?
Cell projection, cilium. Cell projection, cilium, flagellum. Note=Localizes to the midpiece of the sperm flagellum.
Protein: YR592_MIMIV
Sequence: MSFFELDENSPKVDQPHGLKKVKLKDHQLTSIAAMRELETQASIVIDKPEIGSKFHASVGYCISDIEEFKDSTFVIETNSAILADKVGAGKTYTTIGLILKALVPKAHDRHITGTDNFSIKMISAKECEPVNLIVVPHNLINQWADFLDKSKLKYLKLNAESDFNAFLDIDYITKVYPLTREQISCKPIKNKPKKLPVKTTKKGGSKTQNKAQNDQKIYERKSLNMKKIRQALDTHNVFLLNVYRYKLFRQIFLTNKRKWARVIIDEMDSSAVPSIFDEYGNFNWFLTATPSAIFNRSCRRYVNKIFGQRQNLLNYFVVKNKEEYVDKSMILPKPFVFMINTMIQRVVAVFKDLIPQEVLQLINSGNMKEAITKLNCDVDTEENIIKILTGKINTELHNLETELEYVNNLIPQDVDAHENRKKNIMNNIARCKTKLESIKEKINSIKDECCFICTDPFENPTIMNCCKSIFCLKCLLTTLKTVGSKCPYCRHAIKSNKDYQIISSGGTSNKKKKSEIVGKYKFNEMDKADVLEQVLSYISKNDENPKILIFSDYSQTFEKITKNIAKANLQYAYLSGTPAHITNLITEFENGITNILMLNSQNFGSGLNLQSANYLILYHRMLPELETQVIGRAQRFGRKNNLRVIFMVNDNENRDCRLDSKPINILSDSELWMITNPTDLNEEPDEESDEGSDEDVEKSKDKKSSDKKSSDKKKSEKKSSDKKSSNKKNSKKKTYVKPKSSKKTSQKVKKTDSDNESELSGLSDSDDLDDSDDLGILSDSSDSDDFGNLSDSDDLSDSDESEIEIPKKSKKTSKSSKKNKIGGSNKTLKKKAPVRKLIKV
What are the official names of this protein?
Putative helicase R592.
Protein: VPS4A_MOUSE
Sequence: MTTSTLQKAIDLVTKATEEDKAKNYEEALRLYQHAVEYFLHAIKYEAHSDKAKESIRAKCMQYLDRAEKLKDYLRNKEKHGKKPVKENQSEGKGSDSDSEGDNPEKKKLQEQLMGAVVMEKPNIRWNDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEANNSTFFSVSSSDLMSKWLGESEKLVKNLFELARQHKPSIIFIDEVDSLCGSRNENESEAARRIKTEFLVQMQGVGNNNDGTLVLGATNIPWVLDSAIRRRFEKRIYIPLPEEAARAQMFRLHLGSTPHNLTDANIHELARKTEGYSGADISIIVRDSLMQPVRKVQSATHFKKVCGPSRTNPSVMIDDLLTPCSPGDPGAIEMTWMDVPGDKLLEPVVCMSDMLRSLATTRPTVNADDLLKVKKFSEDFGQES
What is the function of this protein?
Involved in late steps of the endosomal multivesicular bodies (MVB) pathway.  Recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly, possibly in combination with membrane fission.  Redistributes the ESCRT-III components to the cytoplasm for further rounds of MVB sorting.  MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids.  It is required for proper accomplishment of various processes including the regulation of endosome size, primary cilium organization, mitotic spindle organization and chromosome segregation, and nuclear envelope sealing and spindle disassembly during anaphase (By similarity).  In conjunction with the ESCRT machinery also appears to function in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis.  Involved in cytokinesis: retained at the midbody by ZFYVE19/ANCHR and CHMP4C until abscission checkpoint signaling is terminated at late cytokinesis.  It is then released following dephosphorylation of CHMP4C, leading to abscission.  VPS4A/B are required for the exosomal release of SDCBP, CD63 and syndecan (By similarity).  Critical for normal erythroblast cytokinesis and correct erythropoiesis (By similarity).
What are the official names of this protein?
Vacuolar protein sorting-associated protein 4A.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Late endosome membrane; Peripheral membrane protein. Midbody. Cytoplasm, cytoskeleton, spindle. Note=Membrane-associated in the prevacuolar endosomal compartment. Localizes to the midbody of dividing cells, interaction with ZFYVE19/ANCHR mediates retention at midbody. Localized in two distinct rings on either side of the Flemming body (By similarity).
Protein: BIOD_BUCA5
Sequence: MIKKFFITGTDTNVGKTIVSSILLKKATMSGYQTAGYKPVSSGGQKKSSGFFNQDAILLKKSSSIILSDREVNPIAFFENAPPHILSKFQKRSIKKEELSLGLSNITKKSNWILVEGAGGWYTPLSCKDTFSSWVKQEKLTVIIIIAIKLGCINHAILTEKAIISDQIKCGGWIANNIFPKDKYNMHYIQTLLNYIKSPFLGVVPYFKNKNRINFKKIKIKLPK
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_ACHLI
Sequence: MAKCYVTGKTTSFGNKRSHALNASRRTWKANLQTVRIKDENGNVKRVKISAKALKKLELERV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: NUDC_YERPS
Sequence: MELQLTGKESGWWIVSHENKLWLPKGELPQGNAANWSLQGATARQIGEWQGQPVWLIRQMMPSGMGSVRQLLDVDRGLFQLAGRGVQLAEFYRSHRFCGYCGHEMHASRTEWASLCNHCRERYYPQIAPCVIVAIRRGDEILLAQHVRHRGGINTVLAGFVEVGETLEQAVSREVLEESNIHIKNLRYVTSQPWPFPHSLMMAFMADYDSGELCHDPKELLNAGWYRYDQLPLLPPPGTVARRLIEDTVVLCREHSDLSQ
What is the function of this protein?
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.  The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing.  Has preference for mRNAs with a 5'-end purine.  Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.
What are the official names of this protein?
NAD-capped RNA hydrolase NudC, DeNADding enzyme NudC, NADH pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudC subfamily.
Protein: NIFB_CHLTE
Sequence: MTLNIKNHPCFNDSSRHTYGRIHLPVAPKCNIQCNYCNRKFDCMNENRPGITSKVLSPRQALYYLDNALKLSPNISVVGIAGPGDPFANPEETMETLRLVREKYPEMLLCVATNGLDMLPYIEELAELQVSHVTLTINAIDPEIGQEIYAWVRYQKKMYRDRQAAELLLENQLAALQKLKRYGVTAKVNSIIIPGVNDQHVIEVARQVASMGADILNALPYYNTTETVFENIPEPDPMMVRKIQEEAGKLLPQMKHCARCRADAVGIIGEINSDEMMAKLAEAALMPKNPDEHRPYIAVASLEGVLINQHLGEADRFLVYALDEEKKSCTLVDSRQAPPPGGGKLRWEALAAKLSDCRAVLVNSAGDSPQSVLKASGIDVMSIEGVIEEAVYGVFTGQNLKHLMKSSQIHACKTSCGGDGNGCD
What is the function of this protein?
Involved in the biosynthesis of the iron-molybdenum cofactor (FeMo-co or M-cluster) found in the dinitrogenase enzyme of the nitrogenase complex in nitrogen-fixing microorganisms.  NifB catalyzes the crucial step of radical SAM-dependent carbide insertion that occurs concomitant with the insertion of a 9th sulfur and the rearrangement/coupling of two [4Fe-4S] clusters into a [8Fe-9S-C] cluster, the precursor to the M-cluster.
What are the official names of this protein?
FeMo cofactor biosynthesis protein NifB, FeMo-cofactor maturase NifB, Nitrogenase cofactor maturase NifB, Radical SAM assemblase NifB.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. NifB family.
Protein: SYP_SHESM
Sequence: MRVSKYLLSTQKETPANAEVISHQLMLRAGMIRRNASGLYSYLPTGLRVLRKVEAIVREEMNKAGAIEILMPMVQPADLWVETGRWDKFGPELLRFKDRHNRDFVLGPTHEEVITDLIRKEVSSYKQLPLNLYQIQTKFRDEVRPRFGVMRSREFLMKDAYSFHLDVDTMNETYEAMYQAYSNILSRMGLAFRPVLADTGSIGGSMSHEFHVLAQSGEDLIAYSTGSDYAANIEKAESPMPTEARGAATEELRLVDTPNAKTIAELVEQFGLDITKTVKTLIVKGATEEAPLVALIVRGDHELNEIKADKLDLVASPLEFAPEALIRDAIGAGPGSLGPVGLNMPIIIDHSVSVMSDFAAGANQDDKHYFGINWERDLPLAQAADIRNVVEGEPTPDGLGTYAMARGIEVGHIFQLGTNYSKSMNATVLDENGKSQVLLMGCYGVGVSRIVAAAIEQNFDDRGIVWPEAIAPFSVGILPMNMHKSHRVTDIAEQLYKDLSAAGIDVLLDDRKERPGVMFADMELIGIPHTVVIGDRNIDAGVFEYKNRRTGEKQDVPFDQIVDFLKNLQA
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: D5_BPT5
Sequence: MSKLNWNVEGVTESLKAKATALGVDVISQEQVAAIAAELAAETGKDVTARSVGSKLRKEGFEVQKANEVQKSPWTPEQEAELVDFLNAHAGQYTYAEIAAAVAGGQFGAKQVQGKILSLEMTASVKPTEKAAAVRSFTPDEETDFVNQVVAGATIEAIAAHFGRNIKQIRGKALSLLREGRIAAMPVQETSSAKTREDLLEGLDLVNMTVAEIAEKTGKSERGVKSMLSRRGLVAKDYDGAAKRAKLDAKAAAAE
What is the function of this protein?
Putative transcription factor required for the expression of viral late genes.
What are the official names of this protein?
Putative transcription factor D5.
Protein: MMM1_USTMA
Sequence: MQQPQQQDLQIGLPYAPVQPPIPSPAAYFAYLPSPSRWTFTQGLIVGQVSMVIVALLLIRYVIFEDSATALEKERLMRLKVSQRRSKLHAKALLQDARKANSAAASAAAAAAPSPASHPLRKSHRLASDTRASMFANILDKTAYDLSSHLPESADWLNVMFAQAIAGYREDVLTGGVSSHHHTASDAIPSPNPLEPQKERTARDLMEEILNRATSSFLDPIRVTEADFGDAYPIFTNARVRPADDTGRTRIEIDVDYSDQITLAIDTKLLINFPKPRFAVLPVSLGLTIVRFSGTLAIELFSSDPNATVLPTANPNPSSSSSSSATPPRSRHQLHFSLHPDFALEASATSLLGSRAKLQDIPKIEQLLISRLRGWIMDRFVWPRYWSLTLPNLVPSPAASRSFSAAAAANRHTDAASVGSSGGHGQINVGTGVERTDASVIQPGHHESARQEMLHAASERPSLASSRPPHVRSSSSGLRANGMGSVEAWRAHAAGVYNQPSHQHATSLNQAALLRAHVGGGGATDCAPGSDVNIEVPGSYRGSVAGAGIELASSSNASSVLPTGAHHSSGLRNRPGFVQ
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Maintenance of mitochondrial morphology protein 1.
What is the protein family that this protein belongs to?
Belongs to the MMM1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: AMPA_RICB8
Sequence: MLHVNFTEEESLNTQALIVFIDDKLKLDSELINLDQQHHGLISKTIANKLQFTGKYGQIKIIPSVVKSGEVKYLVLAGLGSEEKLTEVKIEELGGKILQNVTNAKIATIGLKIKNRISNFTSSHVASLIASGALLASYRFDKYRTTLKEADKFVVESFEISTDNNAEATKLFEVKKLIAEGVFFTRDISNEPSNIKTPQIYAERIADILEELNVDVSILGEREMKNLGMGALLGVGQGSQNESKLVVMEYQGTNKDAPYIALVGKGVIFDTGGISLKPSNNMHLMRYDMCGSAAVVGTMIAVASQELPVNIVGVVGLVENMPSGNAQRPGDVVTTMSGQTAEVLNTDAEGRLVLADAVWYAQEKFKPKCVIDVATLTGAIVVSLGPTYAGCFSNNDELADKLIKAGEEVNEKLWRMPLHEDYDAMINSDIADMANIGNVPGAAGSSTAAHFIKRFIQEGVEWAHLDIAGVANSNKPSSLGPKGAVGYGVRLLEKFIKENYEQ
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YJBB_ECO57
Sequence: MLTLLNLLSAVALLVWGTHIVRTGVMRVFGARLRTVLSRSVEKKPLAFCAGIGVTALVQSSNATTMLVTSFVAQDLVALAPALVIVLGADVGTALMARILTFDLSWLSPLLIFIGVIFFLGRKQSRAGQLGRVGIGLGLILLALELIVQAVTPITQANGVQVIFASLTGDILLDALIGAMFAIISYSSLAAVLLTATLTAAGIISFPVALCLVIGANLGSGLLAMLNNSAANAAARRVALGSLLFKLVGSLIILPFVHLLAETMGKLSLPKAELVIYFHVFYNLVRCLAMLPFVDPMARFCKTIIRDEPELDTQLRPKHLDVSALDTPTLALANAARETLRIGDAMEQMMEGLNKVMHGEPRQEKELRKLADDINVLYTAIKLYLARMPKEELAEEESRRWAEIIEMSLNLEQASDIVERMSSEIADKSLAARRAFSLDGLKELDALYEQLLSNLKLAMSVFFSGDVTSARRLRRSKHRFRILNRRYSHAHVDRLHQQNVQSIETSSLHLGLLGDMQRLNSLFCSVAYSVLEQPDEDEGRDEY
What are the official names of this protein?
Uncharacterized protein YjbB.
What is the protein family that this protein belongs to?
To B.subtilis YqeW.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TSAD_RHIEC
Sequence: MVPFMRILGIETSCDETAAAVVERNAEGHCNVLSDVVLSQLDEHSAYGGVVPEIAARAHVEALDELIEQALKRANVSLADVDAIAATSGPGLIGGLLVGLMTGKAIARAAGKPLYAINHLEGHALTARLTHGLSFPYLVLLVSGGHTQLILVRGVGQYERWGTTIDDALGEAFDKTAKLLGLPYPGGPAVERMARDGNADRFDFPRPLVGEARLDFSFSGLKTAVRQAAQDIAPLSDQDVADICASFQRAISRTLKDRIGRGLQRFKREFPATGEKPALVVAGGVAANLELRATLQALCDKNGFRFIAPPLSLCTDNAVMIAWAGLERMATGVAPDTLDVQPRSRWPLDANAETLIGFGKRGAKA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_CAMJE
Sequence: MKHYEVLFILKPTLTEEEVNTKLEFVKEVLTKNSAEIETVVPMGTRKLAYKIKKYERGTYFVIYFKAPTNLIAELERVLRITEEVIRFLIVKYENKKEIAAWEKLSHGIKQSKKEIKPLDAPEIQ
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: NQRF_VIBPA
Sequence: MDIILGVVMFTLIVLALVLVILFAKSKLVPTGDITISVNGDADKAIVTQPGGKLLSALAGAGVFVSSACGGGGSCGQCRVKVKSGGGDILPTELDHITKGEAREGERLACQVAVKTDMDIELPEEIFGVKKWECTVISNDNKATFIKELKLQIPDGESVPFRAGGYIQIEAPAHHVKYADYDIPQEYREDWEKFNLFRYESKVNEETIRAYSMANYPEEHGIIMLNVRIATPPPNNPDVPPGIMSSYIWSLKEGDKCTISGPFGEFFAKDTDAEMVFIGGGAGMAPMRSHIFDQLKRLHSKRKMSFWYGARSKREMFYVEDFDGLAAENDNFVWHCALSDPLPEDNWDGYTGFIHNVLYENYLRDHEAPEDCEYYMCGPPMMNAAVIGMLKDLGVEDENILLDDFGG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit F, Na(+)-NQR subunit F, Na(+)-translocating NQR subunit F, NQR complex subunit F, NQR-1 subunit F.
What is the protein family that this protein belongs to?
Belongs to the NqrF family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: NUOC_XYLFA
Sequence: MAEQTLSFVDCLTSRFPTVRVSVAQPRGEITLDVPAVEWCAVCRALRDEFDFEQLSDLCGVDYLGYGNTEWDTTDVSAQGFSRGVAGKAVGRFAWGEFPSAGSNDGTQPWDVPQERFAVLAHLISYRHNRRLRVRCFASNDALPIVASLTDVWPGVNWFEREAFDLFGIVFEGHPDLRRILTDYGFIGHPFRKDFPLTGNVEVRYDEEKKRVVYVPVTSVEPRVSVPRVIRDDARFGAAAGESTHSETVK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GST27_SCHMA
Sequence: MAPKLGYWKIKGLVQPTRLLLEYLGEAYEERLYDRNDGDVWRNEKFKLGLDFPNLPYYIDGDVKLTQSMAILRYIADKHNMLGGCPKERAEISMLEGAILDIRYGVSRIAYNKEFETLKVDFLNQLPGMLKMFEDRLSHNTYLNGDKVTHPDFMLYDALDVNLPPIKNYLNSNRYIKWPLQGWSATFGGGDAPPK
What is the function of this protein?
GST isoenzymes appear to play a central role in the parasite detoxification system.  Other functions are also suspected including a role in increasing the solubility of haematin in the parasite gut.
What are the official names of this protein?
Glutathione S-transferase class-mu 26 kDa isozyme, GST 26, Sm26/2 antigen.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Mu family.
Protein: RL21_TRIL1
Sequence: MYAVIKTGGKQYKVAEGDFLKVEKLDNIVGDTIEFGEVLMIGGDAVKVGAPLVAGASVTAKVAVQGRDKKILVFKSKRRKNSRKLIGHRQYHTVLKIEKISA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: PBDC1_MOUSE
Sequence: MDAAGESEEPVSGEALSIAHALSHPPESYGNDPDIEMAWAIRAMQHAEVYYKLISSVDPQFLKLTKVDDQIYSEFREIFETLRVDVLDPEELKSESAKEKWRPFCLKFEGIVEDYNYGTLLRLDCSQGYTEENTIFAPRIQFFAIEIARNREGYNKAVSVSIQDKEGEEGAGNKEEAAEKGADSGGEKEEGANREGEK
What are the official names of this protein?
Protein PBDC1, Polysaccharide biosynthesis domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the PBDC1 family.
Protein: NCAP_UUKS
Sequence: MAMPENWVRFAIEISDAQWEEEEIREFINLFQYQGFDAAVVLSRIFELAKKADLSRDQMLRDIRALITLHLTRGNKLSSIEKRLSEEGKKEFALLKARYQLVDKAKEAADLTLSRIAIANAGLTCRILPQVVAHTAVTRSRMESLSADYPVCMMHNAFAGLIDETLPEDSIKALVDAHRLYLLEFSRTINVKHRGMEAKEILDANDSALQAGLASSFLTPSQKRAYLLSFKLVDGNGKVNKAVQQAATVLRSLI
What is the function of this protein?
Encapsidates the genomic RNA, protecting it from nucleases.  Displays high affinity for single-stranded nucleic acid.  The encapsidated genomic RNA is termed the nucleocapsid (NC) or ribonucleoprotein.  The ribonucleoprotein has a non-helical structure (By similarity).  Serves as template for viral transcription and replication.  After replication, the nucleocapsid is recruited to the host Golgi apparatus by glycoprotein Gn for packaging into virus particles (By similarity).
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the phlebovirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Host nucleus. Host endoplasmic reticulum-Golgi intermediate compartment. Host Golgi apparatus.