PharMolix/UniProtQA huggingface dataset:
Protein: ADHC1_MYCS2
Sequence: MSTVSAYAATSATEPLTKTTITRRAVGPHDVAFDIHFAGICHSDIHTVKAEWGVPNYPVVPGHEIAGVVTEVGSEVTKYKVGDRVGVGCFVDSCRECDNCKAGLEQYCTGTGMVGTYNAIDRDGTPTHGGYSGAIVVDENYVLRIPDSLPLDAAAPLLCAGITTYSPLRHWNAGPGKKVAVIGLGGLGHVAVKLAKAMGADVTVLSQSLKKMEDGLRLGASAYYATSDPETFDKLAGSFDLILNTVSANLDLGAYLGLLKLDGALVELGLPEHPMEVPAFPLLAQRRNLTGSMIGGIPETQEMLDFCAEHDVRPEIEIITPDYINEAYERVLASDVRYRFVIDTASLRS
What is the function of this protein?
Prefers aldehydes over alcohols.
What are the official names of this protein?
NADP-dependent alcohol dehydrogenase C 1, Ms-ADHC 1.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: DER_FLAPJ
Sequence: MNNIVAIVGRPNVGKSTLFNRLIQRREAIVDSVSGVTRDRNYGKSEWNGKEFSVIDTGGYIRGSDDIFEGEIRKQVELAIDESDVIIFVVDVEEGITPMDDAVAKMLRKVTKPVLLAVNKVDNAMREKDAVEFYNLGLGEYYTFASISGSGTGDLLDALIDAFPIKPLPTQEEIVLPRFAVVGRPNAGKSSFINALIGKERFMVTDIAGTTRDSIDTKYDRFGFEFNLVDTAGIRRKAKVKEDLEFYSVMRSVRAIEHADVCILIIDATRGFEGQDQSIFWLAEKNRKGVVILVNKWDLVEKDTMSTRDYEAKIREELMPFVDVPILFVSALTKQRLLKALEATVQVYENRQQRISTSKFNEYMLKIIENHPPPALKGKFVKIKYCMQLPTPTPQFVFFANLPQYVKDAYKRFLENKIRENWDFEGVPIDIYIREK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: GRAN_PONAB
Sequence: MAYPGYGGGFGNFSIQVPGMQMGQPVPETGPGILLDGYSGCPAFSDTYSSAGDSVYTYFSAVAGQDGEVDAEELQRCLTQSGISGTYSPFSLETCRIMIAMLDRDYTGKMGFNAFKELWSALNAWKENFMTVDQDGSGTVEHHELRQAIGLMGYRLSPQTLTTIVKRYSKNGRIFFDDYVACCVKLRALTDFFRKRDHLQQGSANFIYDDFLQGTMAI
What is the function of this protein?
Calcium-binding protein that may play a role in the adhesion of neutrophils to fibronectin.  May play a role in the formation of focal adhesions (By similarity).
What are the official names of this protein?
Grancalcin.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic granule membrane; Peripheral membrane protein; Cytoplasmic side. Note=Primarily cytosolic in the absence of calcium or magnesium ions. Relocates to granules and other membranes in response to elevated calcium and magnesium levels.
Protein: BX7_MAIZE
Sequence: MGHQAQHGTDDTEELLAAHRQLWCHALGYVKSMALKCALDLRIPDTIDRCGGSATLGELLAASEISASNHDYLRRVMRTLTAMRIFAASHDPAKADDAAAISYQLTPASRLLVSSSSSVDDAAGASKENTTTPSILPNIAHLVRPNTISLLFSMGEWMKDESAASVSLYETVHRQGMWACVEDDAANRASFYESMDADTRLVMQAVVRRCPHVFDGIKSLVDVGGGRGTAAAAVVAAFPHIQRCTVMDLPHVVAEAPAGTAGLSFHGGDMFEHIPSADALMLKWILHDWDEDKCIKIMERCKEAIGGKEAGGKVIIIDTVLGSRADDDDDDKTCRETYVLDLHILSFVNGAEREEHEWRRIFLAAGFRDYKITHTRGIPSIIEVFP
What is the function of this protein?
O-methyltransferase involved in the benzoxazinoid glucoside biosynthesis.  Can use 2,4,7-trihydroxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucoside (TRIBOA-glucoside) as substrate, but not aglucone TRIBOA, caffeic acid, ferulic acid, apigenin or quercetin.
What are the official names of this protein?
TRIBOA-glucoside O-methyltransferase BX7, 2,4,7-trihydroxy-1,4-benzoxazin-3-one-glucoside 7-O-methyltransferase, Protein BENZOXAZINONE SYNTHESIS 7.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. COMT subfamily.
Protein: PSB4_NEUCR
Sequence: MEVLLGITGKDFTIIAASKAAMRGATILKASDDKTRSLNKHTLMAFSGEAGDTVQFAEYTQANAQLYSMRNGTDLSPSALANFVRGELATSLRSRKPYNVNLLLGGVDPITHKPSLYWLDYLASLAKVPYAAHGYAQYYCLSILDKHHHPDITLHQGIKLLNLCTDELKRRLPIDFKGMTVKAVTKDGIIDIEFDDDKVVKMA
What is the function of this protein?
Non-catalytic component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity (By similarity).
What are the official names of this protein?
Probable proteasome subunit beta type-4, Proteosome catalytic beta subunit 4.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y1635_SHESR
Sequence: MEQYKIWVDADACPNPIKEMLFRAAERKSVPLVLVANQMLRVPPSPYISQVRVGSGFDVADQYIVDHVEATHLVITADIPLAAHVIEKGALALNPRGELYTTDNIRQKLTMRDFMEDLRSSGVHTGGPDAFSAADKQAFANSLDKWLVRVKR
What are the official names of this protein?
UPF0178 protein Shewmr7_1635.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: Y1313_PASMU
Sequence: MTQLPAVEKQEEHLRLRIFLQPKASKDQIVGLHDNELKITITAPPIDGQANAHLLKFLSKTFKVPKSSIVLEKGELNRHKQILIPNPKVIPTEVNVLLK
What are the official names of this protein?
UPF0235 protein PM1313.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: RL27_ACTPJ
Sequence: MATKKAGGSTRNGRDSEAKRLGVKRFGGESVLAGSIIVRQRGTKFHAGNNVGMGKDHTLFATADGKVKFEVKGEKNRKYVSIVAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: CMAH_XENLA
Sequence: MEQSNDGQTAHTLLHLASAEVESLKEGITFLRNKESGKNFIIYKNGEELRACKNLCKHQGGTFIKDIEDLGNRTVRCTKHNWKLDVSSMKYVNPPDSFCQDELVIENDDENGVSLVELSPPNPWDSDPRMAVCLEGGEVQVTYLTHACMDLKLGNKHMVFDPWLIGPAFARGWWLLHEPPCDWLERLCRADLIYISHMHSDHLSYPTLKKLSEKRPDIPIYVGKTERPVFWYLDKSGVKLTNINVVPFGIWQEVDENLRFMILMDGVHPEMDTCIIVEYKGNKILNTVDCTRPNGGKLPTNVALMMSDFAGGASGFPMTFSGGKFTEEWKSQFIKTERKKLLNYKAQLVKDLNPRIYCPFAGYFVEEHPSDKYIKETNLKNDAAELNMLIRNTSDVVTWTPKPGAILDLGRLLIDPTDKNGIIDPPPGTKIFKDSWDYDTYLSIHSFSFDDEIFHYPSWIKEYFTWAGFKGYNLVLRMIETDEHFVPLPKGYNYLVDFLDLSFPTERPERDHPYEEISSRATVIRHVVKHGLLWDDLYIGFQTRIQRNPDIYHHQFWNHFQIKLPLTPPDWKVFLDREKENNATLQNCSIM
What is the function of this protein?
Sialic acids are components of carbohydrate chains of glycoconjugates and are involved in cell-cell recognition and cell-pathogen interactions.  Catalyzes the conversion of CMP-N-acetylneuraminic acid (CMP-Neu5Ac) into its hydroxylated derivative CMP-N-glycolylneuraminic acid (CMP-Neu5Gc), a sialic acid abundantly expressed at the surface of many cells.
What are the official names of this protein?
Cytidine monophosphate-N-acetylneuraminic acid hydroxylase, CMP-N-acetylneuraminic acid hydroxylase, CMP-N-acetylneuraminate monooxygenase, CMP-Neu5Ac hydroxylase, CMP-NeuAc hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the CMP-Neu5Ac hydroxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMH_SALSV
Sequence: MRQTKTGILLANLGTPDAPTSEAVKRYLKQFLSDRRVVDTPRLLWWPLLRGVILPLRSPRVAKLYQSIWMDGGSPLMVYSREQQQALAARLPDTPVALGMSYGSPSLESAVDELLASDVDHIVVLPLYPQYSCSTVGAVWDELGRILARKRRIPGISFIRDYADDGAYIDALAKSARESFARHGEPDVLLLSYHGIPQRYADEGDDYPQRCRDTTRELVSALGLPPEKVMMTFQSRFGREPWLTPYTDETLKMLGEKGTGHIQVMCPGFAADCLETLEEIAEQNREIFLEAGGKKYAYIPALNATPEHIDMMLKLTAPYR
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCMD2_BOVIN
Sequence: MGGAVSAGEDNDELIDNLKEAQYIRSELVEQAFRAIDRADYYLEEFKENAYKDLAWKHGNIHLSAPCIYSEVMEALDLQPGLSFLNLGSGTGYLSSMVGLILGPFGVNHGVELHSDVTEYAKQKLDFFIRTSDSFDKFDFCEPSFVTGNCLEISPDCSQYDRVYCGAGVQKEHEEYMKSLLKVGGILVMPLEEKLTKITRTGPSAWETKKILAVSFAPLIQPCQSESGKSRLVQLPPLAVRSLQDLARIAIRGTIKKVIHQEAVNKNGNGLKNTPRFKRRRVRRRRLETIVFLDKEVFASRISNPSDDNSSGDLEEERREEEATTPPDAKPEPPVNFLREKVLSLPLPDPLKYYLLYYREK
What is the function of this protein?
May act as a substrate recognition component of an ECS (Elongin BC-CUL5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.  May bind to the methyltransferase cofactor S-adenosylmethionine (AdoMet) via the N-terminal AdoMet binding motif, but probably does not display methyltransferase activity.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK32_SOYBN
Sequence: MAVPKKRTSISKKRIRNTLWKKKGYFTTLKAFSLAQSIFTGNSKSFFCNKYKR
What are the official names of this protein?
50S ribosomal protein L32, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ILVI_BUCSC
Sequence: MEMLSGSEMIIQSLIDQGIKYIFGYPGGAVLDIYDSLKSTKKIKHILVRHEQGATHMADGYARATGKIGVVLVTSGPGATNSITGIATAYMDSIPIVVISGQVSSSLIGYDAFQECDMIGISRPIVKHSFLVKKTEDIPITFKKAFWLASSGRPGPIVIDLPKDILNSYNKKPYIWPIEVNIRSYNPITKGHSRQIKKAIDILKLSKQPVIYAGGGVISANCHNELKELAEKLNIPVTTSLMALGAFPGNHPQNLQMLGMHGTYEANMAMHYADVILAIGVRFDDRTTNNVKKYCPNATIIHIDIDPTSISKTITAHIPIVGNAKNVLQQILVFINSNMFVKEFYCLKKWWIKIQSWKNKNSLNFDTNSDNIKPQSVIKTIWKLTKGKAFITSDVGQHQMFAALYYSFQKPRRWINSGGLGTMGFGLPAALGVKLAFPNETVICVTGDGSIQMNIQELSTAMQYELPILILNLNNKSLGMVKQWQDIIYSGRHSHSYMKSLPNFIKLAESYGHSGISINTPKELEKKLQLALEKLQNGHLVFVDIKIDASEHVYPMQIRDGGMNNMLLRKNGQK
What are the official names of this protein?
Acetolactate synthase large subunit, AHAS, Acetohydroxy-acid synthase large subunit, ALS.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
Protein: SK1_BLACR
Sequence: EQFEDYGHMRF
What is the function of this protein?
Myotropic peptide.
What are the official names of this protein?
Sulfakinin-1, BlaCr-SK-1.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RNH2_ALBFT
Sequence: MLHTPSIKQASLLWDVAGLVAGVDEAGRGPLAGPVVAAAVILDDLQPIKGLADSKILSARRREQLFDEIRAKALCCCIAQASVEEIERLNILQATLLAMRRAVEGLRLKPALVLVDGNRLPVLTMRAEAIVKGDALVAAISAASILAKVHRDRWCAEVDVQYPQYGFARHKGYGTVQHLAALTKHGACPQHRKTFGPVAEVLREALP
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KATG_ACAM1
Sequence: MSSASKCPFSGGALKFTAGSGTANRDWWPNQLNLQILRQHSPKSNPMDKAFNYAEAFKSLDLADVKQDIFDLMKSSQDWWPADYGHYGPLFIRMAWHSAGTYRIGDGRGGAGTGNQRFAPINSWPDNANLDKARMLLWPIKQKYGAKISWADLMILAGNCALESMGFKTFGFAGGREDIWEPEEDIYWGAETEWLGDQRYTGDRDLEATLGAVQMGLIYVNPEGPNGHPDPVASGRDIRETFGRMAMNDEETVALTAGGHTFGKCHGAGDDAHVGPEPEGARIEDQCLGWKSSFGTGKGVHAITSGIEGAWTTNPTQWDNNYFENLFGYEWELTKSPAGANQWVPQGGAGANTVPDAHDPSRRHAPIMTTADMAMRMDPIYSPISRRFLDNPDQFADAFARAWFKLTHRDMGPRSRYLGPEVPEEELIWQDPVPAVNHELINEQDIATLKSQILATNLTVSQLVSTAWASAVTYRNSDKRGGANGARIRLAPQRDWEVNQPAQLATVLQTLEAVQTTFNHSQIGGKRVSLADLIVLGGCAGVEQAAKNAGWYDVKVPFKPGRTDATQAQTDVTSFAVLEPRADGFRNYLKGHYPVSAEELLVDKAQLLTLTAPEMTVLVGGLRVLNANVGQAQHGVFTHRPESLTNDFFLNLLDMSVTWAATSEAEEVFEGRDRKTGALKWTGTRVDLIFGSNSQLRALAEVYGCEDSQQRFVQDFVAAWDKVMNLDRFDLA
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: GABD1_MYCTO
Sequence: MPIATINPATGETVKTFTAATDDEVDAAIARAHRRFADYRQTSFAQRARWANATADLLEAEADQAAAMMTLEMGKTLAAAKAEALKCAKGFRYYAENAEALLADEPADAAKVGASAAYGRYQPLGVILAVMPWNFPLWQAVRFAAPALMAGNVGLLKHASNVPQCALYLADVIARGGFPDGCFQTLLVSSGAVEAILRDPRVAAATLTGSEPAGQSVGAIAGNEIKPTVLELGGSDPFIVMPSADLDAAVSTAVTGRVQNNGQSCIAAKRFIVHADIYDDFVDKFVARMAALRVGDPTDPDTDVGPLATEQGRNEVAKQVEDAAAAGAVIRCGGKRLDRPGWFYPPTVITDISKDMALYTEEVFGPVASVFRAANIDEAVEIANATTFGLGSNAWTRDETEQRRFIDDIVAGQVFINGMTVSYPELPFGGVKRSGYGRELSAHGIREFCNIKTVWIA
What is the function of this protein?
Catalyzes the NADP(+)-dependent oxidation of succinate semialdehyde to succinate.  It is believed to be the main source of succinate semialdehyde dehydrogenase activity in Mycobacterium.  NAD(+) can substitute for NADP(+), but enzymatic activity is three times reduced (By similarity).
What are the official names of this protein?
Succinate-semialdehyde dehydrogenase [NADP(+)] 1, SSADH 1, SSDH 1.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: EIF3L_DROVI
Sequence: MYGGEEFGNSDFYDDYAHTGDPALDLEYERNFYANRMPENVKYFLMNFCQAIKEGNLYDIQNMYENTFPQISDHHFDKTAWPDEQEVGAIVDNDKVFLILYKELYYRHIHARIPGGPKLEQRINSFFNYCDFFNLIISAQNPVMLELPDIWLWELVDEFVYQFQNFAQYRARLTDKSQDEIQQLCVNHSNVWSILCILNVLHSLVDISNIKKQLEAISQGIDPQTVAGDFGKLAFYKMLGYFSLVGLLRVHSLLGDYYQAIKVLEPIEIHKKSAYSHIPACQISTSYYVGFAYMMMRRYADAIRTFSDILLYIQRTKQLYSTRSYQNDQINKQAEQMYHLLAICLVLHPQCIDESIQQVLREKNYHDAMFKMQCGDLEVFKSFFVFACPRFVSPCPPAADAPMEDYVKDPMEHQLLVFMDEVRQQKDLPTTRSYLKLYTTLPLTKLASFIDPNASEDDVSKLLIRLLCFKHKMRNLVWSKGPSGLEGTFKSGSELDFYIDDDMIHIADTKVSHRYGDFFVRKIMKFNDLNRKLKNINI
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit L, eIF3l.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit L family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_YERPB
Sequence: MPVITLPDGSQRHYDHAVSVLDVALDIGPGLAKACIAGRVNGELVDASDLIESDAQLAIITAKDAEGLEILRHSCAHLLGHAIKQLWPDTKMAIGPVIDNGFYYDVDIEHTLTQEDLALLEKRMHELADKDYDVIKKKVSWQEARDTFAARGEDYKVAILDENISRDDRPGLYHHEEYVDMCRGPHVPNMRFCHHFKLQKTSGAYWRGDSKNKMLQRIYGTAWGDKKQLNAYLQRLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELETFVRMKLKEYQYQEVKGPFMMDRVLWEKTGHWENYAEHMFTTSSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGALHGLMRVRGFTQDDAHVFCTEEQVRDEVNSCIKMVYDMYSTFGFEKIVVKLSTRPEKRIGSDELWTRAEDDLAAALTENGIPFDYQPGEGAFYGPKIEFTLHDCLDRAWQCGTVQLDFSLPGRLSASYIGENNDRQVPVMIHRAILGSMERFIGILTEEYAGFFPTWLAPVQVVVMNITDSQSDYVQQVTKKLQDAGIRAKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKIAVRTRRGKDLGSLDVNVVVDQLLAEIRSRSLHQLEE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPS25_MOUSE
Sequence: MAMSFEWPWQYRFPPFFTLQPNVDTRQKQLAAWCSLVLSFCRLHKQSSMTVMEAQESPLFNNVKLQRKLPVESIQIVLEELRKKGNLEWLDKNKSSFLIMWRRPEEWGKLIYQWVSRSGQNNSVFTLYELTSGEDTEDEEFHGLDEATLLRALQALQQEHKAEIITVSDGRGVKFF
What is the function of this protein?
Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.  The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation.  The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex.  The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL (By similarity).
What are the official names of this protein?
Vacuolar protein-sorting-associated protein 25, ESCRT-II complex subunit VPS25.
What is the protein family that this protein belongs to?
Belongs to the VPS25 family.
What are the subcellular locations of this protein?
Cytoplasm. Endosome membrane. Nucleus. Note=Distributes diffusely throughout the cytoplasm and nucleoplasm, but exhibits a punctate distribution on coexpression with CHMP6.
Protein: DPO4_BRUME
Sequence: MAESPIVNHPEQGLCRDCLSLQKTQTSRRCHACGSPRLIRHKELYRLSLAHVDCDAFYASVEKRDNPDLRDKPLIVGGGKRGVVSTACYLARIHGVRSAMPMFKALEACPDAVVIKPNMEKYARVGREVRQMMRDLTPLVEPISIDEAFLDLSGTERLHKAPPAVVLARFSKRVENEIGITASIGLSYCKYLAKVASDLEKPRGFSVIGEAEALDFLRDKPVGMIWGVGKAFAAKLESDGIRTIGQLQTMEEGALMKAYGTMGQRLYRLSRGQDSRKVEPDHDMKSVSAETTFNTDLSAAGDLVPVLRALSEKVSRRLKAGEIAGRTIVLKLKTQDFKLRTRNRQLGDPTQLADRIFRTGLQLLEKEMDGTRFRLLGIGVSDLSPSDRADPPDLVDIQATKRAVAESAIDRLRNKFGLNAVETGYTFSKGNLARTQTPTDRDNEP
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_DESPS
Sequence: MSLHTENSQPSIGVYPGTFDPITNGHIDIIERALALFDTVIVAIAVNGQKQPLFSGEERKEMIEKCFEKEKGRIIVKIVPSGLLVNFAVEQGARAIIRGLRAVSDFDYEFQLALMNRKLVREVESIFLMTAFRWIYISSSLIKDVSKNGGDISDLVPKHVERLLEEKYRP
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VM3_NAJAT
Sequence: MIQPLLVAICLVVFPYQGSSTILESGKVRDYEVVYPQKIPSLPKGRLQRREEKTKYENTMKYEFKVNGEPVVLNLEKNKRLFSKDYTETHYSPDGREITTSPPVQDHCYYHGHIQNDADSTAVIRACDGLNGYFKSNGEMYIIEPLKLSDSEAHAVFKYESLEKEDETPKTCGAIHNSGESDETIKKISNTFVTPEKGEEYLEAEKHIELYMVADNLVYRKYSSNITVVRMRIFEILNYVNLYYKILNIHVVLIGLEVWSDEDKILINGSSELTVRSFAAWRHSDLLKHKRNDNAQLLTGIHFDKRVLGIAFIGGMCNNFTSVGAIQDNSIHAVLIAATMTHELGHNLGMNHDTDSCTCNTGPCIMKAALNFKPPYEFSSCSYWDFQNYIMTKSAQCILNDPLTTDIVPTAICGNGFVEEGEECDCGPPEICKNECCEAATCKLKPEAQCASGACCEECQFRRAGELCRAAKDDCDLDELCTGQSAECPMNHFHMNGHPCQNNQGYCFRGTCPTLTKQCIALWGPDAEVAPDGCFMNNQKGNYYGYCKKKNGTNIPCEPENVKCGRLYCIDDSTEENSCKFHFSNENANSGMVQPGTKCGEGMVCGFGECIGLETALGINQ
What is the function of this protein?
Snake venom zinc metalloproteinase that inhibits platelet aggregation and degrades fibrinogen.
What are the official names of this protein?
Zinc metalloproteinase-disintegrin-like NaMP, Snake venom metalloproteinase, SVMP.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-III subfamily. P-IIIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: OMPU_VIBVU
Sequence: MKKTLIALSVSAAAVATGVNAAELYNQDGTSLDMGGRAEARLSMKDGKVADNSRIRLNFLGKVEIQDGLYGVGFYEGEFTTADNADGSDLDNRYTYAGLGGKFGEVTYGKNDGALGVITDFTDIMAYHGNSAADKIAVADRVDNMMSYKGQFDALSVKASYRFADRADSSKNNVDNTYIDNGKDGYSLSAIYAIGQTGLTLGGGYADQDKSNEYMLAASYTMGDLYFAGVFTDGEKDYGTNGDYSHRGFSSVEDYTGYELAAKYTMGQTVFTTTYNNAETDGYTSTDNFAVDATYYFKPNFRGYVSYNFNLLDAGDKIGTSTISKADAEDELALGLRYDF
What is the function of this protein?
Forms pores that allow passive diffusion of small molecules across the outer membrane.
What are the official names of this protein?
Outer membrane protein U, Porin OmpU.
What is the protein family that this protein belongs to?
Belongs to the Gram-negative porin family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: GPDA_STRP8
Sequence: MTKQKVAILGPGSWGTALSQVLNDNGHDVRLWGNIPDQIEEINTKHTNRHYFKDIVLDKNITATLDLGQALSDVDAVLFVVPTKVTRLVARQVAAILDHKVVVMHASKGLEPETHERLSTILEEEIPAHFRSEVVVVSGPSHAEETIVRDITLITAASKDIEAAKYVQSLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVITRGLAEITRLGVKLGADPLTYSGLSGVGDLIVTGTSVHSRNWRAGAALGRGEKLEDIERNMGMVIEGIATTKVAYEIAQDLGVYMPITTAIYKSIYEGADIKESILGMMSNEFRSENEWH
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_PHOLL
Sequence: MTANAQQLQFIKDSIETIPDYPKPGVLFRDITTLLDNPLAYQATIDLLVERYQGKGITKIVGTEARGFLFGAPVALRLGVGFIPVRKAGKLPRETLSETYNLEYGTDTLEMHKDSVRENDKVLVIDDLLATGGTVEATVRLIRRLGGEVSEAAFIIGLLGLGGVERLQRQGVSSFTLLEFPDH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCMA1_MACMU
Sequence: MSSNIHANHLSLDASSSSSSSSSSSSSSSSSSSVHEPKMDALIIPVTMEVPCDSRGQRMWWAFLASSMVTFFGGLFIILLWRTLKYLWTVCCHCGGKTKEAQKINNGSSQADGTLKPVDEKEEAVAAEVGWMTSVKDWAGVMISAQTLTGRVLVVLVFALSIGALVIYFIDSSNPIESCQNFYKDFTLQIDMAFNVFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLLSIFISTWLTAAGFIHLVENSGDPWENFQNNQALTYWECVYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKRHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLSSAFVGLSFPTVCELCFVKLKLLMIAIEYKSANRESRILINPGNHLKIQEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCGCKRLEDEQPSTLSPKKKQRNGGMRNSPNSSPKLMRHDPLLIPGNDQIDNMDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTVLSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGVLQANSQGFTPPGMDRSSPDNSPVHGMLRQPSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALIAEENALRGGYSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCFGIYRLRDAHLSTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNAGQSRASLSHSSHSSQSSSKKSSSVHSIPSTANRQNRPKSRESRDKQKYVQEERL
What is the function of this protein?
Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+).  It is also activated by the concentration of cytosolic Mg(2+).  Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane.  It therefore contributes to repolarization of the membrane potential.  Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in the cochlea, regulation of transmitter release, and innate immunity.  In smooth muscles, its activation by high level of Ca(2+), caused by ryanodine receptors in the sarcoplasmic reticulum, regulates the membrane potential.  In cochlea cells, its number and kinetic properties partly determine the characteristic frequency of each hair cell and thereby helps to establish a tonotopic map.  Kinetics of KCNMA1 channels are determined by alternative splicing, phosphorylation status and its combination with modulating beta subunits.  Highly sensitive to both iberiotoxin (IbTx) and charybdotoxin (CTX) (By similarity).
What are the official names of this protein?
Calcium-activated potassium channel subunit alpha-1, BK channel, BKCA alpha, Calcium-activated potassium channel, subfamily M subunit alpha-1, K(VCA)alpha, KCa1.1, Maxi K channel, MaxiK, Slo-alpha, Slo1, Slowpoke homolog, Slo homolog.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. KCa1.1/KCNMA1 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.