PharMolix/UniProtQA huggingface dataset:
Protein: CCME_KLEP3
Sequence: MQARRKTRLYIVLAVLAGLGLTVSLTLYALSSNIDLFYTPGEIIYGKTETRALPHTGQRLRVGGYVQPGSLQRDPQTLDVRFKLYDARGVVDVSYKGILPDLFREGQGVVAQGVLDGERHITAQQVLAKHDENYTPPEVKNAMTPEKTGAQP
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: SP8_DANRE
Sequence: MLAATCNKIGSPSPSPSSISDNSSSFGKGFHPWKRATASSCSLGSSLSSFTRNGGGLSDSFGTNTSTGSSAFSLTSGTSSNSHFGNDYSVFQTSVSNNSQEPSHQPMFISKVHTSVDSLQSIYPRMSVAHPYESWFKSSHPGIPTGDVGTTGASAWWDVGAGWIDVQNPNGAALQTSLHSGGLQTSLHSPLGGYNSDYSSLSHSAFSTSASPHLLTTGQHLMDGFKPVLSSYPDSSPSPLGGAGGSMLTGGPTASLAGSPRSSARRYSGRATCDCPNCQEAERLGPAGASLRRKGLHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLSKHVKTHSAGGSSGSGSGASGGKRGSDTDSEHSVPGSPSCHSPDLLQAPESVPTTGMNGRASSLD
What is the function of this protein?
Transcription factor which plays a key role in limb development.  Positively regulates FGF8 expression in the apical ectodermal ridge (AER) and contributes to limb outgrowth in embryos.
What are the official names of this protein?
Transcription factor Sp8.
What is the protein family that this protein belongs to?
Belongs to the Sp1 C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TOP2_PEA
Sequence: MEKRPLQTSNAANIPSKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDEMVHRAVSYVPGLYKIFDEILVNAADNKQRDPSMDSLKVTIDPEANTVSVYNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDNVKKTTGGRNGYGAKLTNIFSTEFIIETADGRRLKKYKQVFSNNMGTKCEPVITKCKASENWTKVTFKPDLEKFKMAYLEEDVVALMKKRVLDMAGCFGKTVKVELNGTLIRFKSFRDYADLFLKCAEKSKPMPLPRIHAKVGDRWEICISLSDGQFQQVSFVNSIATIKGGTHVDYITNQITTYIMNKVNKKKKDANVKAHTVKNHLWVFVNSLIDNPAFDSQTKETLTTRQASFGSKCDVPESMLKDVEKSGIVDTLLSWADFKQSKDLKKTDGTKTQRLRGCKAEDANEAGGRNSEKCTLILTEGDSAKALAMAGLSVVGRDHYGVFPLRGKLLNVREASSKQIMDNEEIQNIKKILGLQQNKEYTNVKSLRYGHLMIMADQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFTTPVIRASHPNKTITSFYSMPEYEAWKERLGNSATSWKIKYYKGLGTSTPQEGREYFSDLGRHRKDFIWDDELDGNAIELAFSKKKAEGRKIWMRNFEPGTCRDHEAKLINYKDFVNKELILFSRADLFGSFKKKLYKEIKVAQFIGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLKPNGQFGTCNLGGKDHASARYIYTELSPVTRCLFHEHDDKLLEYLNEDGKSIEPNWYMPIIPLVLVNGSEGIGTGWSSYIPNYNPREIIANVRRLLNGEELVPMDPWYKGFRGTIEKSAKEGGYIVNGTVTEIDEQTFRITELPIRKWTQDYKQFLESITDGAPNVKDPLIEDFRQNGDDAIVDIEIKMKPEKIATILQEGLFKKFKLTSTISTSNMHLFDAEGNKKFDTPEQILEEFFPLRLDYYEKSKEYILGNLNRLLLILDNKVRFILGVVNGEIIVSNRKKAELLIELKEKGFTPMPRKGKSTKPQVAGANDDDSEEQEDAEPETASQSVSVEGATWGDYDDLLSLPIGTLTLESVQKLLDEKTEKEKEYEILSGTPTTSLWLKDLDEFEKKLDELDLKYAEDDRKRASQGSKKANGFASKPAKKPPQPRKNTKKAKSVEPENDNSSMEIENAVEAAKPAEVAKPKGRAAPKKNIQKEPEDDIQSLQERLAAYNIESSGEKSQAMESEEVQQKAAGKKQNNKRGGAKKKSSTIVLESDSDNEVNDVDDDDDDFEEVQQKAAPVKKGGRKPAAQNAKKAPAKAPAKAPAAPKKRSVGTKQSAGQKLLTDMLQPAEGTGTSPEKKVRKMRESPFNKKSGSILGRAAAAKDISPIADCSAGSASNTPLSEDEVVEIAPQPARARPQRANRTQMKYALSESESEEDSDEDAELSDFEEDDD
What is the function of this protein?
Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands.  Topoisomerase II makes double-strand breaks.
What are the official names of this protein?
DNA topoisomerase 2, DNA topoisomerase II, PsTopII.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase family.
Protein: RIBBA_CORAM
Sequence: MNAPLNSAVRLDSIEEAIADIAAGKAVVVVDNEDRENEGDLIFAAELATPELVAFMVRYSSGYICVPLLPEDCKRLNLPPMMGRNEDVRGTAYTVTVDANTGTTGISATSRAETMLRLADPMSVVDDFTRPGHVVPLAARPNGVLERDGHTEAAIDLARLAGLRPAGVLCEIVSEEDPTTMARSEELRRFSDEHDLKMISIEQLIEWRRHNETQVRRTVETQLPTDFGSFTALGYKHEIDGQEHVALIAGGVEELNGAEDVFVRVHSECLTGDVFHSRRCDCGQQLHQSMEIIQEAGQGIIIYLRGHEGRGIGLLAKLKAYSLQDSGLDTVDANLEQGLPEDAREYSVAGQILRDLGIKSANLLTNNPHKGEGLRGFGVEASAHTPVEIEPNADNIDYLRTKRDRMNHDLPQVARWDAAHALK
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
Riboflavin biosynthesis protein RibBA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the GTP cyclohydrolase II family.
Protein: RL34_RICFE
Sequence: MKRTFQPSNLVRKRRHGFRSRMATPTGRAILRKRRAKGRHKLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: CDNPT_ASPFU
Sequence: MDGEMTASPPDISACDTSAVDEQTGQSGQSQAPIPKDIAYHTLTKALLFPDIDQYQHWHHVAPMLAKMLVDGKYSIHQQYEYLCLFAQLVAPVLGPYPSPGRDVYRCTLGGNMTVELSQNFQRSGSTTRIAFEPVRYQASVGHDRFNRTSVNAFFSQLQLLVKSVNIELHHLLSEHLTLTAKDERNLNEEQLTKYLTNFQVKTQYVVALDLRKTGIVAKEYFFPGIKCAATGQTGSNACFGAIRAVDKDGHLDSLCQLIEAHFQQSKIDAAFLCCDLVDPAHTRFKVYIADPLVTLARAEEHWTLGGRLTDEDTAVGLEIIRGLWSELGIIQGPLEPSAMMEKGLLPIMLNYEMKAGQRLPKPKLYMPLTGIPETKIARIMTAFFQRHDMPEQAEVFMENLQAYYEGKNLEEATRYQAWLSFAYTKEKGPYLSIYYFWPE
What is the function of this protein?
Prenyltransferase that catalyzes reverse prenylation at position N-1 of tryptophan-containing cyclic dipeptides (PubMed:17525915, PubMed:35767141, PubMed:18383240, PubMed:19113967, PubMed:19421461, PubMed:33643664).  Accepts only dimethylallyl diphosphate (DMAPP) as the prenyl donor but shows broad substrate specificities toward its aromatic substrates (PubMed:17525915, PubMed:18383240, PubMed:19113967, PubMed:19421461, PubMed:33643664, PubMed:35767141).  Shows also tryptophan aminopeptidase activity with preference for linear peptides containing a tryptophanyl moiety at the N-terminus (PubMed:18635009).
What are the official names of this protein?
Cyclic dipeptide prenyltransferase, CdpNPT, Tryptophan aminopeptidase CdpNPT.
What is the protein family that this protein belongs to?
Belongs to the tryptophan dimethylallyltransferase family.
Protein: RL51_ORYSJ
Sequence: MGGFVKTQKTNAYHKRFQVKFKRRRQGKTDYRARIRLTNQDKNKYNTPKYRFVVRFTNKDITAQIVYATIAGDIVMAAAYSHELPRYGLEVGLTNYAAAYCTGLLLARRVLKLRGLDQEYEGNIEATGEDYYVEPADERRPFRALLDVGLIRTTTGNRVFGALKGALDGGLDIPHSDKRFAGFKKDEKQLDSDIHRKYIYGGHVADYMRSMAEEEPEKFQAHFSEYLKKGIDADGMEALYKKVHAAIRADPTMAKSTKKEPATHKRYNLKKLTYEQRKASLVERLNALNSSAGADDDDEEEDDE
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L5-1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RS9_TRYBB
Sequence: MRNYNNFNRVWKAPRRPFEKERLDREMKLCGQYGLRCKREIWRVNMTLSKMRRTARLLLTLPENHPRRLLEGSAIMRRCHGYGFLDEDKDKLDYVLSLTVPDILERRLQTVVFKHGLAKSVHHSRVLIQQRHIAVAKQIVTIPSFIVRVSSEHHIAFADASPFGNGRPGRVKRVKRNAAKKGSGGGDDDE
What are the official names of this protein?
Probable 40S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: CLPX_SYMTH
Sequence: MFKFTGEDKGQLKCSFCGKYQDQVKRLVAGPGVYICDECIELCNEIIEEELSEEVDFELKDVPKPAEIKAILDQYVIGQERAKRTLAVAVYNHYKRINLGSKLDDVELQKSNILMLGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDIEKAERGIVYIDEVDKIARKSENPSITRDVSGEGVQQALLKILEGTIASVPPQGGRKHPHQEFIQINTTNILFICGGAFDGIDKIIANRVGRSGLGFGADIRSKQEQNVGELLKQIMPEDLLKFGLIPEFIGRLPIVVTLDALDEDALVRILREPKNALVKQYQKLLQLDNIELEFEEEAVRAIAKEALRRNTGARGLRAIIEDIMTDVMYEVPSRTDVTKCVITKDVVLKKQEPILVTTNDAKSRRTKKEESA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: ALLC_DANRE
Sequence: MAKRQVQKETRSQPHFLQFNNLACETAGGKVIFATDEWFAPARNLLKRDPPEFIASAFTEFGKWMDGWETRRKRIPGHDWCIVQLGVPGIIHGFDVDTSFFTGNYAPFASIQATCLDQMPSIALEGDRTGMAASPSQFEAVAQLNSDSWKEVVPVTKLKAGYSDTCHNYLSVSYPHRVTHIRFNIYPDGGIARLKVYGIGKKDWSSVFGQDLVDLVALVNGGVCVGFSDAHYGHPRNMIGLGMAENMGDGWETARRLDRPRVLKEDENGILQVPGSEWAIFRLGHPGIISKIELDTNHFKGNFPDSCRIEACSLTEDEENSFIQSQWSSDRSPMWNILLPPQKMKAHHRHVFSGPSLVHCGPVSHVRMVIAPDGGISRLRIWGRPVSSHQMISKL
What is the function of this protein?
Utilization of purines as secondary nitrogen sources, when primary sources are limiting.
What are the official names of this protein?
Allantoicase, Allantoate amidinohydrolase.
What is the protein family that this protein belongs to?
Belongs to the allantoicase family.
Protein: RL2_BACC7
Sequence: MGIKKYNPTTNGRRNMTTNDFAEITTDRPEKSLLAPLSKKAGRNNQGKITVRHQGGGHKRQYRIIDFKRNKDGIPGRVATIEYDPNRSANIALINYVDGEKRYILAPKNLEVGMEIMSGAEADIKIGNALPLINIPVGTVVHNIELKPGRGGQLVRSAGTSAQVLGKEGKYVLVRLTSGEVRLVLSACRATVGQVGNESHELIKIGKAGRSRWLGKRPTVRGSVMNPVDHPHGGGEGRSPIGRKSPMSPWGKPTLGFKTRKKNKASDKFIVRRRKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: GATC_BACAH
Sequence: MSRISVENVKHVAHLARLAITDQEAEKFQKQLDAIVTFAEQLNELDTTDVKPTTHVLTMKNVMREDVPEKGLPVEEVLKNAPDHKDNQIRVPAVLE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: RL10_RALPJ
Sequence: MALNLEDKKAVVAEVTAQVAKASTIVVAEYRGITVGDLTKLRAQARQQGVYLRVLKNTLARRAVEGTPFAELAEQLTGPLIYGISEDAVAPAKVLNDFAKGNDKLVLRAGSYDGKVLDVDAVKALATIPSREELLSKLLFVMQAPVSGFARALGALAAKQGEGEAAAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: EPB41_DROME
Sequence: MPAEIKPSAPAEPETPTKSKPKSSSSSHGKPALARVTLLDGSLLDVSIDRKAIGRDVINSICAGLNLIEKDYFGLTYETPTDPRTWLDLEKPVSKFFRTDTWPLTFAVKFYPPEPSQLKEDITRYHLCLQVRNDILEGRLPCTFVTHALLGSYLVQSEMGDYDAEEMPTRAYLKDFKIAPNQTAELEDKVMDLHKTHKGQSPAEAELHYLENAKKLAMYGVDLHPAKDSEGVDIMLGVCASGLLVYRDKLRINRFAWPKILKISYKRHHFYIKIRPGEFEQYESTIGFKLANHRAAKKLWKSCVEHHTFFRLMTPEPVSKSKMFPVFGSTYRYKGRTQAESTNTPVDRTPPKFNRTLSGARLTSRSMDALALAEKEKVARKSSTLDHRGDRNADGDAHSRSPIKNKKEKDADKEAKLREKKQKEKEEKERKEREKRELEEKKKAEKAAKAALAAGAAAGAAVNGNDELNDSNKSDKSSGRRGVGIFSSGRKSKSGSPSKDGKDKSGKDKDKEVGRLGLVVTSGLGDNQQDQNLDEAARNAAKNRGSTTPGVTRQYEYAVDNDGNTSPTRKSYTPGGFRYDQDPNSRKSGADGQEQLSPTSQQKKIGLAFNYAPGNENALKETAEKLKAGQLSPRTQDKLNRGQLSPKSRAKLLQDPLLSPTTRAKLQGSAVDAAAVPLSDSQKRSYSPTKGPQGYSSGAPGSYKPISDPTADFLESQRYNKEPGYVGPSKADVAAGLAGAAGSKKPGSPTKTGKGAPGAAAAAAAGAAGAAAAAAKPKKRRVKIMVITSKFDPSTKRIDAENGSIEHSTGILDPATGLIDTKYGVIDPKKGTLEALNTKTGKKEVFQGDVDGKTGNLHLVSGVADPKTGRLDDTLGQIVCITPQDNPVVELTVITSRIDPATGKIDTVNGDVERSLGVLNLDTGLLDTKYGEINTRTGELKAIDPKSGKIVVSKNVKVDPGTGQITILGIVDPKTNKIDPNQGRLIEVGQQIDPIVEVTSLAGKFDSKRNIIDPKTAQVETSGGQFDPKAGKIDTKYGQIDLVKHTITFNDPKSGKTVTRDIKIEPTTGQIVLKNQVNPKNNKPDKDYARIISLRIVQQRVDPATKAPITEVSASKDKDIVVDPKSNQIWVPTGATDPATKEQQYISSSVDPKTGYVITIYGYLDPKTNEIKKQTKLDPNTIKIEPTSGKIYTATGEVDQATGEPLYAATQVDPESGEVYTKLARVDPKTGKIVIVRILLISKTDERGRPEEIDPSTCEIDPVSGRVLKFFNKTVYVYNMIDPVTGEIVQVDPNDPRFAGARTTVTHTMTLTGEIDPVTGRIKSEYGDIDPNTGDIDPATAVTDPVTGKLILNYAQIDPSHFGKQAQVQTTTETVPITRQQFFDGVKHISKGALRRDSEGSSDDDMTAQYGADQVNEILIGSPAGQAGGKLGKPVSTPTVVKTTTKQVLTKNIDGVTHNVEEEVRNLGTGEVTYSTQEHKADATPTDLSGAYVTATAVTTRTATTHEDLGKNAKTEQLEEKTVATTRTHDPNKQQQRVVTQEVKTTATVTSGDQYQRRDSVSSTSSGDSGTPIDGPYDGASVVRTDNQKSPLFTTSATTGPHVESTRVVLGEDTPGFSGHGEIISTQTVSSKTRTVETITYKTERDGIVETRVEQKITIQSDGDPIDHDKALAEAIQEATAMNPDMTVEKIEIQQQTQ
What is the function of this protein?
An integral component of the septate junction.  May play a role in cell-cell interactions that are necessary for proper development.  Vital for embryonic development.
What are the official names of this protein?
Protein 4.1 homolog, Protein coracle.
What are the subcellular locations of this protein?
Cell junction, septate junction. Note=Septate junction in the apical-lateral domain of epithelial cells during embryonic and imaginal disk development.
Protein: FAD25_MYCTO
Sequence: MSVVESSLPGVLRERASFQPNDKALTFIDYERSWDGVEETLTWSQLYRRTLNLAAQLREHGSTGDRALILAPQSLDYVVSFIASLQAGIVAVPLSIPQGGAHDERTVSVFADTAPAIVLTASSVVDNVVEYVQPQPGQNAPAVIEVDRLDLDARPSSGSRSAAHGHPDILYLQYTSGSTRTPAGVMVSNKNLFANFEQIMTSYYGVYGKVAPPGSTVVSWLPFYHDMGFVLGLILPILAGIPAVLTSPIGFLQRPARWIQMLASNTLAFTAAPNFAFDLASRKTKDEDMEGLDLGGVHGILNGSERVQPVTLKRFIDRFAPFNLDPKAIRPSYGMAEATVYVATRKAGQPPKIVQFDPQKLPDGQAERTESDGGTPLVSYGIVDTQLVRIVDPDTGIERPAGTIGEIWVHGDNVAIGYWQKPEATERTFSATIVNPSEGTPAGPWLRTGDSGFLSEGELFIMGRIKDLLIVYGRNHSPDDIEATIQTISPGRCAAIAVSEHGAEKLVAIIELKKKDESDDEAAERLGFVKREVTSAISKSHGLSVADLVLVSPGSIPITTSGKIRRAQCVELYRQDEFTRLDA
What are the official names of this protein?
Putative fatty-acid--CoA ligase fadD25, Acyl-CoA synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: S2538_USTMA
Sequence: MATASSSDDAGAAMSISIANSSKRPIATTKTAASIPPYATLAFGALSGFASCVLLQPFDLLKTRLQQLDHRPLSPVSNKSISKPQYASRTQKLVAITKDIVHTHGYQGLWRGTAPTVIRNVPGVALYFYSVSHLRSVASQRQIPLISVAIPSDASSNTSTLAKLSTTGNLLTGAVARVTVGFILSPVTVVKARFESSNFSAATERTLLSSMREIRAQSGFRGFFQGFTATALRDAPYAGLYLALYEACKTNLAGLSRSMDGGLGTGNWMVVSASGLLAGTLATLLTHPFDIIKTRMQTTPADTLHQIALAHDPKSTLSPSVLRDSLKPSVWGMTKHLWASSGPRALLDGLGLRCARKAASSAIGWSIFERGRSWYTEREASSSAQEAGTGTRLLDHKQV
What is the function of this protein?
Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix.  Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the mitochondrial matrix.
What are the official names of this protein?
Mitochondrial glycine transporter, Solute carrier family 25 member 38 homolog.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DTD_NOCFA
Sequence: MRVLVQRVTSAQVTVDGEVVGRIEPNPQGLVALVGVTHGDDDATARALADKLWRLRILDGERSAADLGAPILVVSQFTLYADTAKGRRPSWSAAAPGPVAEPLVDAFAATLRELGATVATGRFGAHMHVELTNDGPVTLLLES
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VAPZ_DICNO
Sequence: MAPQRMKNPPHPGLLIKSDLDGLGINITEAAKALDVTRAALSEIINGKRGISAKMAWKLSKAFTNSDPEFWLALQAKYDLSQVGEQCADKVRVLWQPSSLDNEGIEVNSSENKVK
What are the official names of this protein?
Virulence-associated protein A'.
What is the protein family that this protein belongs to?
Belongs to the VapA/VapI family.
Protein: API5A_XENLA
Sequence: MATVEELYRSYGILADAKDDVGQHKSAYQVIIDGVKGGAKEKRLAAQFIPKFFKHFPDLSDSALNAQLDLCEDEDVSIRRQAIKELSQFATGENLPRVADILTQLLQSDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQILQGEDIVRERAIKFLATKMKTLPEETLTKEVDDYIFSESKKVLYDVTGEEFVLFMKILSALKNLQTVSGRQQLVDLVSEQAGLHQTLNPADPDSVDRLLQCMRQAVPLFSKNVHSTKFVTYFCEQVLPILSTLTSPAESIDVQLEVLKLLAEMSSFCGDMDKLESNLNKLFDKLLEFMPLPPEEVENGDTAANEEPKLQFSYVECLLFSFHQLGRKLPDFLIAKVDAEKLKDFKIRLQYFARGLQVYIRQLRLALQGKSGDALKTEENKIKVVALKITNNINVLIKDLFHNPPSYKSTVTLSWKPVQRTPDSGQKRTSDETSSTSPPKKPIVGPKRDSRQIYNPPSGKYSASVGAFSYEQRGGFQGGRGRGWGGRGNRSRGRIY
What is the function of this protein?
May be an antiapoptotic factor.
What are the official names of this protein?
Apoptosis inhibitor 5-A, API-5A.
What is the protein family that this protein belongs to?
Belongs to the API5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: APAH_ACTSZ
Sequence: MSTYFVGDLHGCFDELQKLLERVRFDPVKDKLYFTGDLIARGEKSLECLRFVKNLGTSAQTVLGNHDLHLLACAYGIKKVKTRDNLTALFAAPDFDELMDWLRQQPLLVHNDHFNFSLVHAGISPDWDMATAQACAREVEAVLRQGDYRALLRQMYDSRPERWSSDLQGIERLRYSINVFTRMRFCYADHRLDFDCKLPLEQAPSELMPWFACDNPLFKTENIIFGHWASLVDCPTPGNIYALDTGCAWGNRMTLLRWDDKRIFSQSAVKKTGVF
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: Y1457_MYCBT
Sequence: MMNHARGVENRSEGGGIDVVLVTGLSGAGRGTAAKVLEDLGWYVADNLPPQLITRMVDFGLAAGSRITQLAVVMDVRSRGFTGDLDSVRNELATRAITPRVVFMEASDDTLVRRYEQNRRSHPLQGEQTLAEGIAAERRMLAPVRATADLIIDTSTLSVGGLRDSIERAFGGDGGATTSVTVESFGFKYGLPMDADMVMDVRFLPNPHWVDELRPLTGQHPAVRDYVLHRPGAAEFLESYHRLLSLVVDGYRREGKRYMTIAIGCTGGKHRSVAIAEALMGLLRSDQQLSVRALHRDLGRE
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein JTY_1457.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: RSSA_ARTOC
Sequence: MAPSNLPPIFNATSQDMEMMLTAQCHLGSKNMQTHMEPYLWKTRPDGVNVINIGKTWEKIVLAARIIAAIDNPADICVISARPYGQRAVLKFAAHTGAVAIAGRFTPGSFTNYITRSFKEPRLIVVTDPRTDAQAIKEASYVNIPVIALCDADSPTEFVDVAIPTNNKGRHAIGLVWWMLAREVLRLRGTLASRETEWDIVVDLYFYRDPEAEETKEIEEAKAAEAEEAAPDTLNPADNWDAAGAVAPATFGGTPAAGNWEASGADWATAAPAGGESWAADAPAATEPKW
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein S0.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE_STAMF
Sequence: MLNAYKHSGKAELKPVISKIIAEIPEIRRHVREVIDIVRETINEVNQLPIEKQKEIIEKNWPELLEEKPRTEEKSLPPLPNAAKGRVVTRFAPNPDYTIHLGNARPALLSYWYAEMYEGKMILRFEDTDPRTKAPFPEAYDRIRNDLKWLGIKWNEEYIQSLRLPILYNALRELIKHGGAYVDKCSPKEFKKLRDSGKPCPHRELPPEKHLEELDRIFEGYYSEGEAVVRVKTDLSHPDPSVRDWVAARIIDTSKTPHPIVGDKYILWPTYNLAAAIDDHLMGVTHILRAKEHVSNTIKQKFLYDHMGWKYPETIHFGRLSLEGVILSKSRMRKMIVEYNMEPYDDPRFGTLSGLRRRGIVRETLWRIIKDVGINVIDARISYVNLAAINRSIIDPQAKRYMAIEEALPLKLIGFNNSIEAHVLRHPSTRETYNYIIKPGDIVYISQKDFNIIQNKMFRLMGIGNFALTRPVFSKNYIGFEARLISLSAKEAKQYRAPIIQWVKLEQSIRVKLIIPKETNLETRILLAEKALTNEELGNIVQFYRIGFARIDSKEPEEIKCIFAHE
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLYD_AERHY
Sequence: MKVAPLSVVTLEYTVTDEHGEVIDTTVGKEPLVYLHGTRYLVSGLEAELEGRSVGEAFDVTLTPEQAYGQYDENLVQEVPGELFDGMEVSEGDTFVAETDDGHRPVTVIEVSEEFVKVDGNHPLAGVTLGFKVEIKDVRAATAEELAHGHVHGAGGCGHDHGHDHDHDHGHEHGGYCGGGHHGHDHGHDHGDDHGHGGCCGGGGCGAKGHQH
What is the function of this protein?
Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step.  This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity (By similarity).
What are the official names of this protein?
FKBP-type peptidyl-prolyl cis-trans isomerase SlyD, PPIase, Metallochaperone SlyD.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VE6_HPVME
Sequence: MALFHNPEERPYKLPDLCRTLDTTLHDVTIDCVYCRRQLQRTEVYEFAFGDLNVVYRDGVPLAACQSCIKFYAKIRELRYYSESVYATTLETITNTKLYDLSIRCMCCLKPLSPAEKLRHLNSKRRFHKIAGNFTGQCRHCWTSKREDRRRTRQETQV
What is the function of this protein?
Plays a major role in the induction and maintenance of cellular transformation.  E6 associates with host UBE3A/E6-AP ubiquitin-protein ligase and modulates its activity.  Protects host keratinocytes from apoptosis by mediating the degradation of host BAK1.  May also inhibit host immune response.
What are the official names of this protein?
Protein E6.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E6 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: CLPX_KOCRD
Sequence: MARIGESVDLLKCSFCGKSQKQVRKLIAGPRVYICDECIELCNEIIEEELTEVTEADQTELPRPKQVYDHLQEYVIGQEPAKRSLAVAVYNHYKRIRAGVSGHTLSLAGAEGDEEAIEVAKSNILLVGPTGSGKTYLAQSLAKKLDVPFAVADATSLTEAGYVGEDVENILLKLIQAADFDLKKAEQGIIYIDEIDKISRKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPQQEFLHIDTTNVLFIVAGAFAGLEEIVQQRTGKKGIGFGAPIRDTADVDIAGQVQPEDLLKFGLIPEFIGRLPVVATLSKLSVADMVRILTEPRNALVKQYRKLFQLDGVELTFDPQALEAIAELALERGTGARGLRAILEDILMPVMFDLPGREDVAAVLVTEDAVAKLADPEIFTHEMIEAERRRHKSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: ASTE_YERPY
Sequence: MLDFLAITLSGKPPQVIQGETVNLKWQWLGEGILTLVPHRSYTQSVVISAGIHGNETAPIEILNQLVTDLLAGQLTLAVRLLVLLGNPPAIRKGKRYLSNDINRMFGGRYQHYTPSDETRRASTLEQRVMAFFQASHTSERLHYDLHTAIRGSYHPRFGLLPYQQTPYSAAMFRWLRDIELDALVMHTSAGGTFAHFSSERCQAASCTLELGKALPFGENQLSQFSAITQGLRSLVSDSALPARKTENMKYYRVVKSLLRQHPDFKLRGAEDTVNFTRFAQGTLLTEQPNDNYRVEHPYEWILFPNPHVALGLRAGMMLVKMCESELPIT
What is the function of this protein?
Transforms N(2)-succinylglutamate into succinate and glutamate.
What are the official names of this protein?
Succinylglutamate desuccinylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.