PharMolix/UniProtQA huggingface dataset:
Protein: BZR1_ORYSI
Sequence: MTSGAAAAGRTPTWKERENNKRRERRRRAIAAKIFTGLRALGNYNLPKHCDNNEVLKALCREAGWVVEDDGTTYRKGCKPPPSSAGGASVGMSPCSSTQLLSAPSSSFPSPVPSYHASPASSSFPSPSRIDNPSASCLLPFLRGLPNLPPLRVSSSAPVTPPLSSPTASRPPKIRKPDWDVDPFRHPFFAVSAPASPTRGRRLEHPDTIPECDESDVSTVDSGRWISFQMATTAPTSPTYNLVNPGASTSNSMEIEGTAGRGGAEFEFDKGRVTPWEGERIHEVAAEELELTLGVGAK
What is the function of this protein?
Positive brassinosteroid-signaling protein.  Mediates downstream brassinosteroid-regulated growth response and feedback inhibition of brassinosteroid biosynthetic genes.  May act as transcriptional repressor by binding the brassinosteroid-response element (5'-CGTGCG-3') in the promoter of GRAS32 (AC Q9LWU9), another positive regulator of brassinosteroid signaling (By similarity).
What are the official names of this protein?
Protein BZR1 homolog 1, OsBZR1, Protein BRASSINAZOLE-RESISTANT 1 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the BZR/LAT61 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Brassinosteroid promotes nuclear localization and binding to GF14C is required for cytoplasmic retention and efficient inhibition of BZR1 when brassinosteroid levels are low.
Protein: SBT_PETHY
Sequence: MTCICIFSIAFLLSFHLTTAQRSTGLQTYIVHVDKPDAQVLANSADLESYYNSFLPATVSGSEVPSRIIHSYHHVATGFAAKLSGEEVKEMEKKAGFVSAKLEKVLTLHTTHTPNFLGLYQNMGFWQESNYGKGVIIGLLDTGITPGHPSFSDVNMPSPPAKWKGKCEFTGNATCNKKIIGARNFISGSGVPPTDEEGHGTHTASTAAGNFVNDANVFGNANGTAVGMAPLAHIAMYKVCSEDGCSDADILAALDAAIDDGVDVLSLSLGGYSDPFYYDNIAIGAFAAIRKGIFVSASAGNDGPLNSTLSNEAPWILTVGASTHDRKIVATAVLGNGQQYDGESAFQPADFPHTLLPLVYPGTSDEEAAFCSSGSLDKFDVKGKVVVCDRGGDVARLEKSQTVKDAGGAAMILANLEIDGEGTFADAHVLPATHVGYAAGEMIKSYINSTSTPTAGILFKGTIIGFKSSPSVSSFSSRGPNLASPGIVKPDIIGPGVNILAAWPVSVENKTGTDLTFNIISGTSMSCPHLSGIVALLKSAHPDWSPAAIKSAIMTSADQSNLEGQPILDERNLPADIFATGAGHVNPSKASDPGLIYDIQLEDYIQYLCGLGYREKDIGLIVQETVKCESSISEAELNYPSFSIILGPKTQNYTRTVTNVGDASSTYTVNIAKTQGVDIVVEPATLVFTKMYQQATYTVSFTQSGDFTDRFVQGAISWSSNEYVVRSPISVKLE
What is the function of this protein?
Required for arbuscular mycorrhiza (AM) development during AM symbiosis with AM fungi (e. g.  Glomeromycota intraradices).
What are the official names of this protein?
Subtilisin-like protease, Subtilase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast. Note=Accumulates in the intercellular spaces and the periarbuscular space (PAS) during arbuscular mycorrhizal (AM) symbiosis.
Protein: 3SPM_DENJA
Sequence: RICYNHLGTKPPTTETCQEDSCYKNIWTFDNIIRRGCGCFTPRGDMPGPYCCESDKCNL
What is the function of this protein?
Inhibits ADP-induced platelet aggregation and inhibits the binding of purified platelet fibrinogen receptor alpha-IIb/beta-3 (ITGA2B/ITGB3) to immobilized fibrinogen (PubMed:1591238).  Has also been described to inhibit cell adhesion to fibrinogen, fibronectin, laminin and collagen (PubMed:16798616, PubMed:11336631).
What are the official names of this protein?
Dendroaspin, Glycoprotein IIb-IIIa antagonist, Mambin, Platelet aggregation inhibitor.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Antiplatelet toxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PAND_MARMS
Sequence: MQITLLKGKLHMASVTQAELWYDGSCAIDKDLVELAGFREFEQIDIYNVDNGERFHTYVILAESGSGTISMNGAAARKVQVGDRVIIAAYGQMNEAEADEFKPKLVYLNKDNSVERTTNTIPVQKD
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MPAG4_DACGL
Sequence: DIYNYMEPYVSKVDPTDYFGNEQARTAWVDSGAQLGELSYGVLFNIQYVNYWFAP
What are the official names of this protein?
Major pollen allergen Dac g 4.
Protein: DEF_SALEP
Sequence: MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEGIGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGNPFELEADGLLAICIQHEMDHLVGKLFIDYLSPLKQQRIRQKVEKLDRLNARA
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: PHC3_MOUSE
Sequence: MDSEPSSGTSVSTTASSTTTTTITTSSSRMQQPQISVYSGSDRHAVQVIQQALHRPPSSAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQASLSSGRPSTSPTGSVTQQSSMSQTSILSASPAPAQLMNRSQTSSSTSGSITQQTMLLGSTSPTLTASQAQMYLRAQMLIFTPATTVAAVQSDIPVVSSSPSPSCQSAAAQVQNLTLRSQKLGVLSSSQNGSPKSAGQTQSLTICHNKTTVTSSKISQRDPSPESKKGGSPGLESRSTAVTRTSSIHQLIAPASYSPIQPHSLIKHQQIPLHSPPPKVSHHQLLLQQQQQQIQPITLQSPSQDPPPSQHCIPLPNHGLSPAPSNAQPQHCSPVQSHPPPLTVSPNQAQSAQQSVVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSSALQTGPNLQQAAADQVQSTAQLNLPSHLPLPASPVVHIGPVQQSALVSPGQQMVSPTSHQQYSALQSSPIPIATPPQMSASPPAQLPPLPLQSMQSLQVQPEILSQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPVDPPVVYQVEDVCEEEMPEESDECARMDRTPPPPTLSPAAVTVGRGEDLTSEHPLLEQVELPAVASVSASVIKSPSDPTHASAPAPPLLIPAASTRSSSTSLASSTPSLENKPPQAIVKPQILTHVIEGFVIQEGLEPFPVSRSSLLIEQPVKKRPLLDNQVVNSVCVQPELQNNTKHADNSSDTEIEDMMAEETLEEMDSELLKCEFCGKMGYPNEFLRSKRFCTMSCAKRYNVSCSKKFALSRWNRKPDNQSLGHRGRRPSGPEGAAREHILRQLPITYPSAEEDVASHEDPVPSAMTTRLRRQSERERERELRDVRIRKMPENSDLLPVAQTEPSIWTVDDVWAFIHSLPGCQDVADEFRAQEIDGQALLLLKEDHLMSAMNMKLGPALKICARINSLKDS
What is the function of this protein?
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development.  PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (By similarity).
What are the official names of this protein?
Polyhomeotic-like protein 3.
What are the subcellular locations of this protein?
Nucleus.
Protein: RSMH_NAUPA
Sequence: MRIEDIPHIPVLLNETIGLYNDMPENGYFIDCTLGFGGHSEAILEKYPNIKLIGIDQDAEAMHFAKNRLARFGDRVQFINKRASSALEELPEDLPVSGILADIGVSSYQLDNKERGFTFESEELDMRMDKTQDFSAKDVVNFYSKEDLERIIKNYGECRRFKKVVSAIISKRPIKSNRELADILGHIGLRDKKDLAKIFQAIRIEVNNELNELEKILKNAKKLAKNGTILGIITFHSLEDRIVKNTFKEWSKKCICPPEAIRCECGGNNQLGKILTKKPLVASKEEIKMNPRSRSAKLRGFQFIRG
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TUSC_ECO81
Sequence: MKRIAFVFSTAPHGTTAGREGLDALLATSALTDDLAVFFIADGVFQLLPGQKPDAVLARDYIATFKLLGLYDIEQCWICAASLRERGLDPQTPFVVEATPLEADALRRELANYDVILRF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
What are the official names of this protein?
Protein TusC, tRNA 2-thiouridine synthesizing protein C.
What is the protein family that this protein belongs to?
Belongs to the DsrF/TusC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPEE_CLOK5
Sequence: MDLWLREGQIEDAAMTYKIKETLVTKKTKYQELAIVDTYALGRMLVLDGIVQTTVKDEYVYHEMITHIPLFTHPNPQKVLIVGGGDGGTVREVLKHETVEKVVLCEIDEQVVYECKKYLPEISCELDNPKCEVFIGDGIKYVHQHRNEFDVIIVDSTDPFGAAEGLFGGSFYKEIYNCLTEDGIFIAQTETPFYLPEVVKQVYKDAKEIFPITRLFMAGIPTYPSGFWSFTIGSKKYDPKEVDLSSTLNINTKYYTKELHKACFVLPKFVEDLTR
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOF_SALPC
Sequence: MSWQQRVDDALTARRATDTLRRRYVVSQGAGRWLVANGRQYLNFSSNDYLGLSQHPQIIRAWQQAATRFGVGSGGSGHISGYSVAHRALEEELAQWLGYPRALLFISGFAANQAVITALMKKNDRIVADRLSHASLLEAANLSPAQLRRFIHNDTQHLSRLLQSPCVGQQLVVTEGVYSMDGDSAPLAEIQHIARRHHAWLLVDDAHGIGVTGDEGRGTCCQRGVKPELLVVTFGKGFGVSGAAVLCSESVADYLLQFARHLVYSTSMPPAQAQALSASLAVIRSDEGRERREKLAALVQRFRAGVNASRFTLLNAHSAIQPLIVGDNSRALRLAEALRQQGCWATAIRPPTVPVGTARLRLTLTQAHEACDIDRLLEVLHGAGE
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: NU6C_WHEAT
Sequence: MDLPGPIHEILMLFGGFVLLLGGLGVVLLTNPIYSAFSLGLVLVCISLFYFLLNSYFVAVAQLLIYVGAINVLIIFAVMFVNGSEWSKDKNYWTIGDGFTSLVCITIVFSLMTTIPDTSWYGILWTTRSNQIVEQGLINNVQQIGIHLATDFYLPFELISIILLVSLIGAITMARQ
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 6, chloroplastic, NAD(P)H dehydrogenase subunit 6, NADH-plastoquinone oxidoreductase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: UGT9_GARJA
Sequence: MFPWLAYGHISPYLELAKRLTDRGFAIYICSTPINLGFIKKRITGKYSVTIKLVELHLPDTPELPPHYHTTNGLPPHLMATLKRALNGAKPELSNILKTLKPDFVIYDATQTWTAALTVAHNIPAVKFLTSSVSMLAYFCHLFMKPGIEFPFPAIYLSDFEQAKARTAAQDARADAEENDPAAERPNRDCDSIFLVKSSRAIEGKYIDYLFDLMKLKMLPVGMLVEEPVKDDQGDNSNELIQWLGTKSQRSTVLVSFGTEYFLTKEEMEEIAHGLELSEVNFIWVVRFAMGQKIRPDEALPEGFLERVGDRGRIVEGWAPQSEVLAHPSTGGFICHCGWNSVVESIEFGVPVIAMPMHLDQPLNARLVVEIGAGMEVVRDETGKFDRKEIARAIKDAMVEKTGENTRAKMLDVKGRVELKEKQELDEVAELLTQLVTETTQSSN
What is the function of this protein?
Glucosyltransferase catalyzing the beta 1-6 glucosylation of the sugar moiety of crocetin glucosyl esters to produce crocetin gentiobiosyl esters.  Weak activity toward curcumin glucosides, but no activity with flavonoid glucosides, coumarin glucosides, 4-nitrophenyl glucoside or crocetin.  Involved with UGT75L6 in sequential glycosylation of crocetin to crocin (bis(beta-D-gentiobiosyl) crocetin).
What are the official names of this protein?
Beta-D-glucosyl crocetin beta-1,6-glucosyltransferase, UDP-glucose glucosyltransferase 9, GjUGT9, UDP-glycosyltransferase 94E5.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: CSLAB_ARATH
Sequence: MQEDLELGNQNFPMVLVQIPMYNEREVFKLSIGAACRLIWPLDRLIVQVLDDSTDPTIMEMVSTECGKWATKGINIKCERRDNRNGYKAGALKQGMRHSYVKTCTYIAIFDADFQPEPDYLERTVPFLIHNPELALVQARWKFVNAKKCLMTRMQEMSLNYHFTAEQESGSTRHAFFGFNGTAGVWRLAAMEEAGGWKDRTTVEDMDLAVRVGLHGWKFVFVNDVSVKSELPSQFKAFRFQQHRWSCGPANLFRKMTMEIIRNKRVTIWKKLYVIYSFFFVRKIIVHFFTFFFYCFILPTSVFFPEVNIPTWSTVYFPFMITLFNAIATPRSFYLVIFWVLFENVMAMHRTKGTFIGLLEGGRVNEWVVTEKLGDALETKLLPQVRKPRNGFLERINSKEMMVGIYILCCASYNLVFGKTVLYIYLYMQALAFIIAGIGFIGT
What is the function of this protein?
Probable mannan synthase which consists of a 4-beta-mannosyltransferase activity on mannan using GDP-mannose.  The beta-1,4-mannan product is the backbone for galactomannan synthesis by galactomannan galactosyltransferase.  Galactomannan is a noncellulosic polysaccharides of plant cell wall.
What are the official names of this protein?
Probable glucomannan 4-beta-mannosyltransferase 11, Cellulose synthase-like protein A11, AtCslA11, Glucomannan synthase, Mannan synthase 11.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. Plant cellulose synthase-like A subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: RSMG_LIMF3
Sequence: MNPEEFRQALLDHGIALTDAQMAQFARYYQLLVQTNEHLNLTAITAETEVYLKHFYDSLTGAFAYPKLQSQALTLCDIGAGAGFPSLPLKIAFPQLEVTIVDSLNKRINFLADLCDDLGLTGVYLVHDRAETFAAKGSPYREQFDLVTARAVARLVVLGELCLPAAKVGGAFLAYKASAVNDELKLATGAINKLGGQVAGTTKLTLPTKPEAEERNLVVIDKVAKTPGKYPRRPGVPAKKPLINV
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DBAC_EMENI
Sequence: MAQLYDWLVETPANAEDLESRINTRPAHLEHNKPLIEAGTLVWGGPSLAAHPKAAGEDLAIVGSVMCIRAGSEEEVREMIRNDPYAKLGQVSIRMSVK
What is the function of this protein?
Part of the gene cluster that mediates the biosynthesis of the antibiotic 2,4-dihydroxy-3-methyl-6-(2-oxopropyl)benzaldehyde (DHMBA) and its derivatives (PubMed:22510154, PubMed:23001671).  The direct non-reducing polyketide synthase dbaI product is 2,4-dihydroxy-3-methyl-6-(2-oxopropyl)benzaldehyde (DHMBA), produced by condensation of one acetyl-CoA starter unit with 4 malonyl-CoA units and one methylation step (PubMed:22510154).  The FAD-dependent monooxygenase dbaH is responsible for the synthesis of yellow pigments derived from the oxidation of DHMBA (PubMed:23001671).  The roles of dbaB, C, E and F have still to be determined (Probable).
What are the official names of this protein?
Derivative of benzaldehyde biosynthesis cluster protein C.
What is the protein family that this protein belongs to?
Belongs to the YciI family.
Protein: RTCA_PONAB
Sequence: MAGPRVEVDGSIMEGGGQILRVSTALSCLLGLPLRVQKIRAGRSTPGLRPQHLSGLEMIRDLCDGQLEGAEIGSTEITFTPEKIKGGIHTADTKTAGSVCLLMQVSMPCVLFAASPSKLHLKGGTNAEMAPQIDYTVMVFKPIVEKFGFVFNCDIKTRGYYPKGGGEVIVRMSPVKQLDPVNLTDRGCVTKIYGRAFVTGVLPFKVAKDMAAAAARCIRKEIRDSYVNIQPVQEPKDQAFGNGNGIIIIAETSTGCLFAGSSLGKRGVNADKVGIGAAEMLLANLRHGGTVDEYLQDQLIVFMALANGVSRIKTGPVTLHTQTAIHFAEQIAKAKFIVKKSEDEEDAAKGTYIIECQGIGMTNPNL
What is the function of this protein?
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA.  The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product.  The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity).
What are the official names of this protein?
RNA 3'-terminal phosphate cyclase, RNA cyclase, RNA-3'-phosphate cyclase, RNA terminal phosphate cyclase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm.
Protein: NPY1_CAEEL
Sequence: MPTFRSNIVVFNLIARRAFTTTSTKNMGFVEKVRLLDYWKIQDSALQSEFPRSRLVLMVDRRLLVTKDQPDVQMVELSFDDLKQRLGEYGLQFDLSNSCLLDALSTDVDMIPLFGTSIDAADPPEDSPISKKEVLKQLGNSLGGRFTDIRMAMLTMREERQRNLLAKFQSLTKWASIYRRCPKCAAALKMRSSKSGAECVTCQRVYYPTFSPVSITLITDPTNEHALLVRHRGSAGGVFTAVAGFAHSGESMAECARREIAEEVGIEVDSIRSLDMSQPWPMPDSSLMIAHVAVAKIDQKISVCPDELETAQWFTRHQVKEALTTTLADPLLKNLPRTLDDRQTLHYIPPAGAIAHQMIRQWVDGKLENHNSRI
What is the function of this protein?
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.  The NAD-cap is present at the 5'-end of some RNAs; in contrast to the canonical N7 methylguanosine (m7G) cap, the NAD cap promotes mRNA decay (By similarity).  Mediates the hydrolysis of some nucleoside diphosphate derivatives (PubMed:10873676).
What are the official names of this protein?
NAD-capped RNA hydrolase ndx-9, DeNADding enzyme ndx-9, NADH pyrophosphatase, Nudix hydrolase 9.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudC subfamily.
Protein: TRUA_CAUSK
Sequence: MPRYRLTIEYDGRPYNGFQAQASQPSVQGAIEAAVKAFTGQTIRIAAAGRTDTGVHATAQVVHVDLERDWPAETVMNALNAHLVREAISVLDAVVVSDDWHARFSANERRYLYRILNRRAPPALERGKVWHVKKPIDADAMQTAAQALVGLHDFTTFRDMACQAKSPLKTLDVARVSRVGDEVHLVFEARSFLHRQVRSMTGTLAEVGVGRWTADDVMAALEARDRTACGPVAPADGLYLTGVGYEGEG
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: MUTS_ACAM1
Sequence: MSDSVAPDVPVIREGKNPAQHRDRTTVDREALSPMMRHYVDLKDEYPQTILLYRMGDFYETFFEDACTIAQALELVLTSRQSGNEVGRVAMAGIPHHQLDRYSRLLVEKGFAVAICDQMEDPAQAQGLVKREVTRVITPGTLLEEGMLNARSNNFLAAFVLAGNHWGLAYADISTGEFLTTQFSERETLAQELLRLQPSEVLFPTDAPDIQQILRPGEQSDLLPEGLPNQFCYSLRSQTSFTQAEARQRIQEVYGVRSLEGLGCEHLPLAVRAAGGLLAYLEATQKDTHIPLQPLATYTLSQYLVLDHQSRRNLELTQTSRDGTFRGSLLWAIDRTRTAMGSRALRRWLLQPLLDLNDIQARQAAITELLPQTGFRKELQNQLQKIYDLERLAGRAGSGTANARDLVALAESLGQLTELSHKVAKCEAQYLQALQTVPPILDQLAQRLRAHLVESPPISLTEGGLIKPSVNPELDQMRQQIVSDQQWIANLEKDERERTGISTLKVGFNKAFGYFISISRAKADQAPDDYIRKQTLTNEERFITPELKEREARIFTAQTEQFQLEYDLFVTLRTEVGEQASLIRTVAAAVSAVDILVGLTEVAVYQGYCCPTMSDSREIQILDGRHPVVEQSLPPGFFVPNATELGSAPSAELTPHPDLVILTGPNASGKSCYLRQVGLIQLMAQIGSYVPAQSARLGICDRIFTRVGAVDDLATGQSTFMVEMNETANILNHASSKSLVLLDEIGRGTATFDGLAIAWSVAEHLAAVIQARTIFATHYHELNELASLVENVANYQVLVKELPDQIIFLHQVCPGGASRSYGIEAGRLAGLPPSVIKRAKQVMKQIEQHSKIAVGLRKGNTQPRARKSSAETEAKTQQFELPF
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: RL6_RHOPB
Sequence: MSRVGKKPVVVPSGVTASVQGQIVTMKGPKGQLQFIVHDDVEVQFENGSVTVKPRVETNRARALYGTARAQVANLLEGVTKGFEKKLDITGVGYRAALQGKKLQLALGYSHDVVYDIPDGITITVPKPTEIFISGNDSQRVGQVAAEIRSYRPPEPYKGKGVRYSDEFIFRKEGKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: HELY_MYCLE
Sequence: MTDLAELARFTAELPFSLDDFQQRACAALERGHGVLVCAPTGAGKTVVGEFAVHLALAAGGKCFYTTPLKALSNQKYTDLTARYGRNRIGLLTGDQSVNGDSPVVVMTTEVLRNMLYADSFALQGLSHVVMDEVHFIADRMRGPVWEEVILHLPDDVRMVSLSATVSNAEEFGGWVQTVRGDTTVVVDEHRPVPLWQHVLVGKRLFDLFDYDSNVDQSPVNPNLLRHIAHCREADRMSDWRNPRRRAGRGSGVRPRFYRSLARPEVIAILDAEGLLPAITFVFSRFGCDAAVQQCLRSPLRLTSEEERAQIAEVIDHRCGDLADADLAVLGYYEWREGLLRGLAAHHAGMLPAFRHAVEELFTAGLVKAVFATETLALGINMPARTVVLERLVKFNGKQHVPLTPGEYTQLTGRAGRRGIDVEGHAVVIWHPSEDTSGPSAVAGLASARTFPLRSSFVPSYNMTINLVHWMSPERAHALLEQSFAQYQADRSVVGLVRGIERCTQVLGDISSELGGPDAPILEYARLRARIAEMERAQSFVFRLQRKQAANDVLAALRRGDIITITHGRHGGLAVVLESARDSSNPRPLVLTEHRWAGRISSADYMGAAAPVGSMTLPKRVEHRQQRVRRDLASALRSAATRLSVPDIGDGVDGDKIGFNDGVLHDPELASLRAQLRRHRSNNAPGLDTQLQQAERYLRIERYNAQLQRKVAAATNSLARTFDRIVGLLIERDFIRGPADDPQVTDDGRLLARIYSESDLLVAECLRTGAWAGLRPAELAAVVSAVLYETRGDDGPGGPVDAEAPTPRLRQALQHTSRLSATLRADEQRHRIALSREPDDGFVGVIYCWARTGDLAAVLAAADASGNGAPLSAGDFVRWCRQVLDLLDQLRNAAPEPDLRATAKRAINDVRRGVVAVDAG
What are the official names of this protein?
Probable helicase HelY.
What is the protein family that this protein belongs to?
Belongs to the helicase family. SKI2 subfamily.
Protein: NUD22_RAT
Sequence: MDPEVSLMLLCPPGGLSQEQVSVELSPAHDRRPLPEGDKTITAIWETRLQAQPWIFDAPKFRLHSATLASSSPEPQLLLHLGLTSYRDFLGTNWSSSASWLRQQGATDWGDKQAYLADPLGVGAALVTADDFLVFLRRSQQVAEAPGLVDVPGGHPEPQALCSGSIPQHEDLPGELVVRELFSSVLQEVCDEVNLPLHTLSQPLLLGIACNETSAGRASAEFYVQCSLTSEEVRNYYLSGGPEANESTGIIFVETQRVQRLQETEMWAQLCPSAKGAILLYNRHPPLQSGAGKSHLSHPSVPALSLQL
What is the function of this protein?
Hydrolyzes UDP-glucose to glucose 1-phosphate and UMP and UDP-galactose to galactose 1-phosphate and UMP.  Preferred substrate is UDP-glucose.
What are the official names of this protein?
Uridine diphosphate glucose pyrophosphatase NUDT22, UDPG pyrophosphatase, UGPPase, Nucleoside diphosphate-linked moiety X motif 22, Nudix motif 22.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
Protein: PURL_PYRIL
Sequence: MGLTQRELEIIRERLGREPTAAELAFFTSHWSEHCSYKSTKMWLRELPGSAPWVVRGRGTDAPLVEVAHGLYVSFKIESHNHPSAVDPYNGAATGVGGIIRDILTVGATPIALLVNLHFGPPEDPHAKWIFSNVIKGISDYGNRVGVPVVGGETWFDEDFTYTPIVLATCVGVVEAEAVPKGYVEPGDYIVVAGLGADRSGLGGSAFASKTLEGGEDLGAIQVADPLMGKKLIDVVKEVSRCVKFIKDLGGGGLATALAELSHWFSLGVEFHLDKLHVRDASALPEELLISETQERLIFVISPRDLPCLEEALRKYEVPYSIPGRFVKSDRVLVMWKGVKIVDIPISLADGAPEILWPQEPYQPSDIPEIPEPPIDKAIDIVLSSPNVAKKESIYMRFDFDVGVRTAVKPGEGDAAVLKLYQRGQLGLVVKGDANPRYTFLDPRLGAANAFVKAYRNVAVVGGVPLAAVDSINVGSPERPQVYWRFVQAVQGLKEAATELEVPIVGGKVSLYNEYMGRPIKPTVAVVVLGKIDDVSKANRALWHDGDKIYIWGVTKGEVGGSEYLKRVHGILAGRPPSIDYAAEKEIVAVIQSWLGKISGATDVGLGGLITALAKMAINSGIGGEIDVCKAPAETTRLDYLLFSESNGRFIATGAEGPGVAIGEAYGEEFVVKCGGTLIYKRGVEELKRLMSL
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EMID1_HUMAN
Sequence: MGGPRAWALLCLGLLLPGGGAAWSIGAAPFSGRRNWCSYVVTRTISCHVQNGTYLQRVLQNCPWPMSCPGSSYRTVVRPTYKVMYKIVTAREWRCCPGHSGVSCEEASSASLEPMWSGSTMRRMALRPTAFSGCLNCSKVSELTERLKVLEAKMTMLTVIEQPVPPTPATPEDPAPLWGPPPAQGSPGDGGLQDQVGAWGLPGPTGPKGDAGSRGPMGMRGPPGPQGPPGSPGRAGAVGTPGERGPPGPPGPPGPPGPPAPVGPPHARISQHGDPLLSNTFTETNNHWPQGPTGPPGPPGPMGPPGPPGPTGVPGSPGHIGPPGPTGPKGISGHPGEKGERGLRGEPGPQGSAGQRGEPGPKGDPGEKSHWGEGLHQLREALKILAERVLILETMIGLYEPELGSGAGPAGTGTPSLLRGKRGGHATNYRIVAPRSRDERG
What are the official names of this protein?
EMI domain-containing protein 1, Emilin and multimerin domain-containing protein 1, Emu1.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.