PharMolix/UniProtQA huggingface dataset:
Protein: ATPA_HELPS
Sequence: MSQLKLEEISSVIEEKIKNFELDCDMAEVGKVVSYADGVAKVYGLNGVMSYEVLEFETGDKGVAANLEEDSVGVIVFGFGNNIKEGTSVKRTKSLMKVPVGDAVVGRVLNALGEPIDGKGEIETNEFSLIEQKAPGIMDRKSVHEPLQTGIKAIDALVPIGRGQRELIIGDKQTGKTTVAIDAIINQKGQNVICIYVAIGQKESTVAQVVRKLEEYGAMEYSVVINASASDSAAMQYLAPYSGVAMGEYFRDHARHALIIYDDLSKHAVAYREISLILRRPPGREAFPGDVFYIHSRLLERAAKLCDEKGAGSLTALPIVETQAGDVSAYIPTNIISITDGQIFLETDLFYSGIRPAINVGLSVSRVGGAAQIKATKQVSGTLRLDLAQYRELQAFTQFASDLDEASKKQLERGQRMVEVLKQAPYSPLPIEKQVVIIYAGAKGFLDSVSVKKVVDFEEQLHPFLEAKYPQVLEEIHTKKVLDKDLEAMLRKVLEEFKLTYSE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SQS1_CANAL
Sequence: MPKRGNRRRRGGTGGSGGGRGGRGGSRGRGGGRRTPSGANRGRHPSRGNKNRSPRTITQYGDLMDDDNIFIPKTMSEVASNMGRRKYGGMFEEIEYTESHQEDLMSRQLRNRPVEFVKAKEVYDPNVILYKLAKLNNKDDGIDIAVQSISLDDSENESSTNKVDISSSEEIEESGDEYEDEQDDEDDWDEEELHNEITTKLEALEEAMNNVSSDTESEQSVSHIEEEDEKVESHIPEPDLSAEVDEPLQEIDESENENQMESEVGTNTNTQDIETLDIIIDLPSNKVESHMSHSLPQKFKTPSSPDDDNDDNNNNSTPESEPEYGYLEEDYEFDVSKIEVSNVRFGIENQYHIKCMELTGSIDEYIWIDENDVIEYVLDNGVKEHRLNKFLSFITKGMIDEQEPEPEPEVYISDSNSEEEEEEEDDYNSEQDDYPYDSDDNLEDLIAYSKTSTQGLIPFEDRDFSNNIPSKKRQTFDHLDFDDDGELQDSLIRQLNNYKANKKLKKHQWEQQKLEESILHHDMLIKYPVSLHIKDIKSEFDQLLKDESRQSMSFPTLDTHGHKTIKNLADCYHMSVIKSGKQGIRKYLKIVKNKATFKYYPNYERINRILRGRPIFHRIDQKPQHKKGEKSKSKSSRGDASSSRARFKEGDIVGAEAPEIGSSNLGRQMLEKLGWIQGQGLGVDGNKGINEPILAKVKTSKTGIK
What is the function of this protein?
May be involved in splicing.
What are the official names of this protein?
Protein SQS1.
What is the protein family that this protein belongs to?
Belongs to the SQS1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: THIE_RHIEC
Sequence: MRLDPFYLIVDSADWVERLVPLGVKLVQLRIKDRPEPVLREEIRRAKAACAAAACQLIINDYWRLAIDEGCDFIHLGQEDLMAADLAAIRRAGLKLGLSTHDPSELETALAAAPDYVALGPVWPTILKEMKWAPQGVERLADWRRRVGPMPLVAIGGITAERAPLVLENGADSAAVVTDITRNPDPEARTRQWLAATAPWRSVG
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: RS12_STRT2
Sequence: MPTINQLVRKPRQSKVVKSKSPALNVGYNSHKKVQTNVSSPQKRGVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGALDTAGVADRKQSRSKYGAKRPKG
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RL23_LEPBP
Sequence: MNLENVILSPVVTEKSQDLQTIGERMGKRTVKYTFKVHPDANKTLIKQALKQMYNVVPTNVNVAVYRGKMKRFRNMPSQRPHYKKAVVTFADGANLDFAKV
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: KS6A4_HUMAN
Sequence: MGDEDDDESCAVELRITEANLTGHEEKVSVENFELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHTRTERSVLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGEIVLALEHLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEFLTEEKERTFSFCGTIEYMAPEIIRSKTGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPPRIGPVAQDLLQRLLCKDPKKRLGAGPQGAQEVRNHPFFQGLDWVALAARKIPAPFRPQIRSELDVGNFAEEFTRLEPVYSPPGSPPPGDPRIFQGYSFVAPSILFDHNNAVMTDGLEAPGAGDRPGRAAVARSAMMQDSPFFQQYELDLREPALGQGSFSVCRRCRQRQSGQEFAVKILSRRLEANTQREVAALRLCQSHPNVVNLHEVHHDQLHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVVHRDLKPENILYADDTPGAPVKIIDFGFARLRPQSPGVPMQTPCFTLQYAAPELLAQQGYDESCDLWSLGVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRFSLDGEAWQGVSEEAKELVRGLLTVDPAKRLKLEGLRGSSWLQDGSARSSPPLRTPDVLESSGPAVRSGLNATFMAFNRGKREGFFLKSVENAPLAKRRKQKLRSATASRRGSPAPANPGRAPVASKGAPRRANGPLPPS
What is the function of this protein?
Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factor RELA, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes.  Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin.  Plays an essential role in the control of RELA transcriptional activity in response to TNF.  Phosphorylates 'Ser-10' of histone H3 in response to mitogenics, stress stimuli and EGF, which results in the transcriptional activation of several immediate early genes, including proto-oncogenes c-fos/FOS and c-jun/JUN.  May also phosphorylate 'Ser-28' of histone H3.  Mediates the mitogen- and stress-induced phosphorylation of high mobility group protein 1 (HMGN1/HMG14).  In lipopolysaccharide-stimulated primary macrophages, acts downstream of the Toll-like receptor TLR4 to limit the production of pro-inflammatory cytokines.  Functions probably by inducing transcription of the MAP kinase phosphatase DUSP1 and the anti-inflammatory cytokine interleukin 10 (IL10), via CREB1 and ATF1 transcription factors.
What are the official names of this protein?
Ribosomal protein S6 kinase alpha-4, S6K-alpha-4, 90 kDa ribosomal protein S6 kinase 4, Nuclear mitogen- and stress-activated protein kinase 2, Ribosomal protein kinase B, RSKB.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: NCAP_CVHN1
Sequence: MSYTPGHYAGSRSSSGNRSGILKKTSWADQSERNYQTFNRGRKTQPKFTVSTQPQGNTIPHYSWFSGITQFQKGRDFKFSDGQGVPIAFGVPPSEAKGYWYRHSRRSFKTADGQQKQLLPRWYFYYLGTGPYANASYGESLEGVFWVANHQADTSTPSDVSSRDPTTQEAIPTRFPPGTILPQGYYVEGSGRSASNSRPGSRSQSRGPNNRSLSRSNSNFRHSDSIVKPDMADEIANLVLAKLGKDSKPQQVTKQNAKEIRHKILTKPRQKRTPNKHCNVQQCFGKRGPSQNFGNAEMLKLGTNDPQFPILAELAPTPGAFFFGSKLDLVKRDSEADSPVKDVFELHYSGSIRFDSTLPGFETIMKVLEENLNAYVNSNQNTDSDSLSSKPQRKRGVKQLPEQFDSLNLSAGTQHISNDFTPEDHSLLATLDDPYVEDSVA
What is the function of this protein?
Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M.  Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, NC, Protein N.
What is the protein family that this protein belongs to?
Belongs to the betacoronavirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum-Golgi intermediate compartment. Host Golgi apparatus. Note=Located inside the virion, complexed with the viral RNA. Probably associates with ER-derived membranes where it participates in viral RNA synthesis and virus budding.
Protein: RL7_TREDE
Sequence: MAALTNEQIIEAIGEKTILELSELIKAMEEKFGVTAAAPVAVVAGGAAGGGAAEEEKTEFTVTLKGLSDPGKKIGVIKEVRNVIPGLGLKEAKELVEGAPKVLKEDVSKEEAAKIKEAITAAGGEVEIA
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: ULA1_CHICK
Sequence: MAQPGRASLKEQRYDRQLRLWGDHGQEALESAHVCVINATATGTEILKNLVLPGIGSFTIVDGNRVSGEDVGNNFFLQKSHIGQSRAQSATELLQELNNDVSGNFVEESPETLLDNDPSFFNRFNLVVATQLSESTVLRLAELLWNSNIPLLICRTYGLVGYMRIIIKEHPVVESHPDNALEDLRLDKQFPELTEHIQSYDLDHMDKKDHSHTPWIVIVAKYLTKWFNEKSDQLPKSYKEKEAFRQLIRQGILKNENGTPEDEENFEEAIKNVNTALNTTKIPRCIEEIFNDDCCVNLTEQSPSFWILVRAVKEFVANEGQGCLPVRGTIPDMIADSSKFIKLQNVYREKAKRDIAAVGNHAAKLLQSLGKAPESISERELKLLCSNSAFLRVVRCRSLSEEYGLNTFNKDEIISNMDNPDSEVVLYLMLRAVDRFYKQHGRYPGVYNYQVEDDIGKLKSCLTSFLQEHGLSVLVKDDYVHEFCRYGAAEPHAIAAFMGGAAAQEIIKVITGQFVIFNNTYIYSGMSQTSATFQL
What is the function of this protein?
Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme.  E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP.  E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M (By similarity).
What are the official names of this protein?
NEDD8-activating enzyme E1 regulatory subunit, APP-BP1, Amyloid protein-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
Protein: YNPI_CAEEL
Sequence: MASPHAENDMVPEMIDHRHLQMWKWLHSRSGARGNTSETSFESSVSVSTNSFDFSADMSRSIDSSSSRMLPSPITNFVTPSSSFSSHQMHDIYSLAASYLQAPPPPYTPTTAFHPHNAHQLLLLHNMTAAVQTPEDPDIDVVGLADTTNLVSLNDKEDEEKLDQTTESEESDRISISTTEECPLDLTFKPTSLDSPTSSTFIPLRPSVIIDHHIPKPHTSVRRSMSSVSSSASSTQEEVAAHFRRSLSGKWPKRCKVNSEEARNSPLRRRPSFNTHTSVSSLSVHSVSPTPPVTSSAQTIIVNNHCSDTTLSVADHFRRALLGKGLFDFQRKSNK
What are the official names of this protein?
Uncharacterized protein R08C7.12.
Protein: GATA_LISMH
Sequence: MGLFDFSVKELHDKLVKKEISPFDLVSESFNRIESVEDKVGSFITLNKEAAFGVAEELGDAGIDPNNMLAGLPIGIKDNIVTKSLRTTAASKILENFDPIYDATVVSKLKNAQTINIGKLNMDEFAMGSSTETSYFHKTHNPWDLSRVPGGSSGGSASAVAAGEVLFSLGSDTGGSIRQPAAFCGVVGMKPTYGRVSRFGLIAFASSLDQIGPITKNVEDNAYLLEAISGLDANDSTSINQPVERFSDSLTGDIKGLRIGVPKEYLGEGVDPGVKQAVLDALKTLEKLGATWDEVSLPHSEYGVASYYILASSEASSNLSRFDGVRYGYRSPNATTLEELYTKTRSEGFGDEVKRRIMLGTYALSSGYYDAYYKKAQQARTLIKQDFVNVFENYDVIIGPSSPTTAFKIDGMINDPITMYSNDILTVPINLAGVPAISVPCGFSDGLPVGLQIIGNYFEESLLYKVAHAFEQETTFHKEKPNL
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: ITPA_PEDHC
Sequence: MSRPLVFVTGNAKKLEEVVTILGNNFPAKLVSQSVDLPELQGEIEDICKKKCLEAAKIVQGPVLVEDTCLCFNALGGLPGPYIKWFLEKLGPEGLSKLLTGWEDKTATAICTIAYSSGDQNEDVILFQGQTTGKIVEPRGTRIFGWDPCFLPDGYDQTYAEMPKSEKNKISHRTKAVEKLRTYFTEKLNF
What is the function of this protein?
Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives.  The enzyme does not distinguish between the deoxy- and ribose forms.  Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine triphosphate pyrophosphatase, ITPase, Inosine triphosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: JAPL_RHISA
Sequence: MKVLLCLVCSFYIIVSSITTMTTGTPSMPAINRQTLYLAAYSSKLFSWNVGCVKTRHLSQEGDWVTRSLIYVFTFDKKPWETKADAFKVKWEPYSPLLRVQASDYVKYNLRAKPEYFIRTYDDDFLLLSDVKESRSPCSLWVTLKYVERIPETINRTFYANCPDPVTVPFDERCYP
What is the function of this protein?
Salivary tick protein that modulates host immune response.  This protein blocks dendritic cell (DC) differentiation from monocytes (PubMed:23825947).  In addition, it inhibits up-regulation of costimulatory molecules and pro-inflammatory cytokines in response to stimuli and promotes up-regulation of co-inhibitory molecules and the anti-inflammatory cytokine interleukin-10.  It has a pocket to accomodate cholesterol, which may have immune-modulatory roles, either directly or through interactions with the host gut microbiota (By similarity).
What are the official names of this protein?
Japanin-like-RS.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
Protein: VPK9_HUMAN
Sequence: WASQVSENRPVCKAIIQGKQFEGLVDTGADVSIIALNQWPKNWPKQKAVTGLVGIGTASEVYQSMEILHCLGPDNQESTVQPMITSIPLNLWGRDLLQQWGAEITMPAPLYSPTSQKIMTKRGYIPGKGLGKNEDGIKIPFEAKINQKREGIGYPF
What is the function of this protein?
Retroviral proteases have roles in the processing of the primary translation products and the maturation of the viral particle.  Endogenous Pro proteins may have kept, lost or modified their original function during evolution (By similarity).
What are the official names of this protein?
Endogenous retrovirus group K member 9 Pro protein, HERV-K(C6) Pro protein, HERV-K109 Pro protein, HERV-K_6q14.1 provirus ancestral Pro protein, Protease, Proteinase, PR.
What is the protein family that this protein belongs to?
Belongs to the peptidase A2 family. HERV class-II K(HML-2) subfamily.
Protein: KCRM_HUMAN
Sequence: MPFGNTHNKFKLNYKPEEEYPDLSKHNNHMAKVLTLELYKKLRDKETPSGFTVDDVIQTGVDNPGHPFIMTVGCVAGDEESYEVFKELFDPIISDRHGGYKPTDKHKTDLNHENLKGGDDLDPNYVLSSRVRTGRSIKGYTLPPHCSRGERRAVEKLSVEALNSLTGEFKGKYYPLKSMTEKEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKSFLVWVNEEDHLRVISMEKGGNMKEVFRRFCVGLQKIEEIFKKAGHPFMWNQHLGYVLTCPSNLGTGLRGGVHVKLAHLSKHPKFEEILTRLRLQKRGTGGVDTAAVGSVFDVSNADRLGSSEVEQVQLVVDGVKLMVEMEKKLEKGQSIDDMIPAQK
What is the function of this protein?
Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e. g.  creatine phosphate).  Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
What are the official names of this protein?
Creatine kinase M-type, Creatine kinase M chain, Creatine phosphokinase M-type, CPK-M, M-CK.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.
Protein: PGM1_MOUSE
Sequence: MVKIVTVKTQAYPDQKPGTSGLRKRVKVFQSNANYAENFIQSIVSTVEPALRQEATLVVGGDGRFYMTEAIQLIVRIAAANGIGRLVIGQNGILSTPAVSCIIRKIKAIGGIILTASHNPGGPNGDFGIKFNISNGGPAPEAITDKIFQISKTIEEYAICPDLKVDLGVLGKQQFDLENKFKPFTVEIVDSVEAYATMLRNIFDFNALKELLSGPNRLKIRIDAMHGVVGPYVKKILCEELGAPANSAVNCVPLEDFGGHHPDPNLTYAADLVETMKSGEHDFGAAFDGDGDRNMILGKHGFFVNPSDSVAVIAANIFSIPYFQQTGVRGFARSMPTSGALDRVANATKIALYETPTGWKFFGNLMDASKLSLCGEESFGTGSDHIREKDGLWAVLAWLSILATRKQSVEDILKDHWQKFGRNFFTRYDYEEVEAEGANKMMKDLEALMLDRSFVGKQFSANDKVYTVEKADNFEYSDPVDGSISKNQGLRLIFADGSRIIFRLSGTGSAGATIRLYIDSYEKDVAKINQDPQVMLAPLISIALKVSQLQERTGRTAPTVIT
What is the function of this protein?
This enzyme participates in both the breakdown and synthesis of glucose.
What are the official names of this protein?
Phosphoglucomutase-1, PGM 1, Glucose phosphomutase 1, Phosphoglucomutase-2.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRSA2_BACAN
Sequence: MRGKHIFIITALISILMLAACGQKNSSATVATATDSTITKSDFEKQLKDRYGKDMLYEMIAQDVITKKYKVSDDDVDKEVQKAKSQYGDQFKNVLKNNGLKDEADFKNQIKFKLSMNKAIKQSVTEKDVKDHYKPEIKASHILVSDENEAKEIKKKLDTGASFEELAKQESQDLLSKEKGGDLGYFHSGAMTPEFETAAYKLKIGQISDPVQSPNGYHIIKLTGKKDLKPYDEVKNSIRKNLEEERTADPIFGKKLLQSELKKANIKINDSELEDTFTIVSPQGN
What is the function of this protein?
Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.  Important for the secretion of the protective antigen.  The three PsrA proteins in this organism show different but overlapping substrate specificities.
What are the official names of this protein?
Foldase protein PrsA 2.
What is the protein family that this protein belongs to?
Belongs to the PrsA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: ENLYS_BPPA2
Sequence: MPPSLRKAVAAAIGGGAIAIASVLITGPSGNDGLEGVSYIPYKDIVGVWTVCHGHTGKDIMLGKTYTKAECKALLNKDLATVARQINPYIKVDIPETTRGPLYSFVYNVGAGNFRTSTLLRKINQGDIKGACDQLRRWTYAGGKQWKGLMTRREIEREVCLWGQQ
What is the function of this protein?
Signal-arrest-release (SAR) endolysin with lysozyme activity that degrades host peptidoglycans and participates with the pinholin and spanin proteins in the sequential events which lead to programmed host cell lysis releasing the mature viral particles.  Once the pinholin has permeabilized the host cell membrane, the SAR-endolysin is released into the periplasm where it breaks down the peptidoglycan layer.
What are the official names of this protein?
SAR-endolysin, Endolysin, Lysis protein, Lysozyme, Muramidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 24 family.
What are the subcellular locations of this protein?
Host cell inner membrane; Single-pass type II membrane protein; Periplasmic side. Note=Secreted as a signal-anchored, membrane-tethered, inactive endolysin which is subsequently refolded, activated and released by membrane depolarization driven by the pinholin.
Protein: ASRC_SALTI
Sequence: MSIDIDIIKARAKNEYRLSKVRGEAMISVRIPGGILPAHLLTVARDIAETWGNGQIHLTTRQKLAMPGIRYEDIDNVNAALEPFLREIEIELCDVQVEDTKAGYLAIGGRNIVACQGNRICQKANTDTTGLSRRLEKLVYPSPYHLKTVIVGCPNDCAKASMADLGIIGVAKMRFTADRCIGCGACVKACSHHAVGCLALKNGKAVKEESACIGCGECVLACPTLAWQRKPDQLWQVRLGGRTSKKTPRVGKLFLNWVTEDVIKQVIVNLYEFEKEMLGGKPIYLHMGHLIDKGGYLRFKERVLRGVQLNPEAMVAERIYWAEDESVARMHLKPAGH
What is the function of this protein?
This enzyme catalyzes the hydrogen sulfide production from sulfite.  It is strictly anaerobic.  It is regulated by electron acceptors rather than by cysteine (By similarity).
What are the official names of this protein?
Anaerobic sulfite reductase subunit C.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOD_GEOKA
Sequence: MSVHIGAKTGEIAERILLPGDPLRAKYIAETFLEGAVCYNEVRGMLGFTGTYKGERISVQGTGMGVPSISIYVNELIQSYGVKTLIRVGTCGAIQPDVRVRDVILAMSASTDSNMNRLIFRGRDYAPTADFHLLRTAYEVGVEKGLALKVGNVFTADMFYNDEPNWETWARYGVLAVEMETAALYTLAAKFGCRALSVLTVSDHILTGEETTAEERQMTFNEMIEVALEAAIRNGA
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: PGK_WIGBR
Sequence: MKIIKVTDLNLKDKKVLIRSDLNVPIKNGKIMCNMRIIKSLETINFVIKNEAKCVIVASHLGNPIEEKYDYNFSLTHIVNHMKKIIKYPIRLIQNYLNGFEAKEKEIIVLENVRFNPGERKNDKNLSKKYANLCDILVMDSFGSSHRSESSTTGIIKFAPISCIGLLFLKEIKYLKKALFNSKRPIVTIFGGSKISTKLGVIEKLSNISENVLVGGGIANTILFSKGHNIGKSLHDKNNISKIKKFLYKKNIIIPKDFIVTDNINKFSSYKEKSIKEIKNEDYIVDIGKKSCECFIKIIKKAKTIFWNGPLGLIEIKQFRNGTKEIANSVIHSSAKSIIGGGETVLAMRMFNFIDRFSYISTGGGAFLSFIEKQELPVLSELKKFKKYTNFKQN
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBB_CHAVU
Sequence: MGLPWYRVHTVVLNDPGRLIAVHIMHTALVSGWAGSMALYELAVFDPSDPILDPMWRQGMFVIPFMTRLGITKSWGGWSITGETITNPGIWSYEGVAAVHIILSGLLFLAAIWHWVYWDLELFRDERTGKPALDLPKIFGIHLFLSGLLCFGFGAFHVTGLFGPGIWISDPYGITGKVQSVSPAWGAEGFDPFNPGGIASHHIAAGILGILAGLFHLSVRPPQRLYKALRMGNVETVLSSSIAAVFFAAFIVSGTMWYGSAATPIELFGPTRYQWDQGYFQQEIDRRVRLSTSQGFSISEAWSRIPEKLAFYDYIGNNPAKGGLFRAGPMDNGDGIAVGWLGHAVFKDKEGHELFVRRMPTFFETFPVVLVDEEGIIRADLPFRRAESKYSIEQVGVTVEFYGGELDNVSFSDPATVKKYARRAQLGEIFEFDRTTLKSDGVFRSSPRGWFTFGHLCFALLFFFGHIWHGARTLFRDVFAGIDPDIDSQIEFGIFQKLGDPTTKKQTV
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP47 reaction center protein, PSII 47 kDa protein, Protein CP-47.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: Y2994_LEGPH
Sequence: MTQEKGKFAEQLALNYLKENGLALVMQNYHCRLGEIDLIMREGSYLVFVEVRSRSNMNFGGGLASITYEKKQKIIKATSHYMIKYRIQDKFPIRFDVISIDGKSNKITWLKNAFDAGC
What are the official names of this protein?
UPF0102 protein lpg2994.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: RS21_BLOFL
Sequence: MPIIKVRENEPFDVALRRFKRSCEKAGILSEVRRREFYEKPTTERKRAKASAIKRHIKKINREQLKKSRSF
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: HEM6_SALDC
Sequence: MKPDAHHVKQFLLRLQDDICQKLSAVDGANFVEDSWRREAGGGGRSRVLRNGGIFEQAGVNFSHVHGDAMPASATAHRPELAGRSFEAMGVSLVVHPHNPYIPTSHANVRFFIAEKPGADPVWWFGGGFDLTPYYGFEEDAVHWHRTARDLCQPFGDDVYPRYKKWCDDYFFLKHRNEQRGIGGLFFDDLNTPDFDHCFAFMQAVGNGYTEAYLPIVERRKAMVWGERERNFQLYRRGRYVEFNLVWDRGTLFGLQTGGRTESILMSMPPLVRWEYDWQPEAGSPEAALSEFIQVRDWI
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_AERHH
Sequence: MIQMQSMLGVADNSGARSVMCIKVLGGSHRRYAGIGDIIKVSIKEAIPRGKVKKGDVYNAVVVRTRKGVRRPDGSVIRFDNNAAVLLNNNQQPIGTRIFGPVTRELRNEKFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: GUAA_YERPB
Sequence: MTKNIHKHRILILDFGSQYTQLLARRVREIGVYCELWAWDVTEAQIREFNPSGIILSGSPESTIENGSPRAPDYVFTAGVPVLGVCYGMQTMAIQLGGKVESSNQREFGYAQVEIKADSALIRDIKDAINPAGEAVLDVWMSHGDKVAEIPADFVTVASTDTCPFAIMANEEKRFYGVQFHPEVTHTKQGLRLLERFVLGICGCEALWTSATIIEDAIVRLREQIGDDHVILGLSGGVDSSVTAMLLHRAIGKRLTCVFVDNGLLRLNEADQVLEMFGDKFGLNIVHVAAEDRFLSALAGVDEPEAKRKIIGRVFVELFDEEACKQEQVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKLGLVEPLKELFKDEVRKIGLELGLPYDMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELHKADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETVDFMTAHWAHLPYDFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.