PharMolix/UniProtQA huggingface dataset:
Protein: SDHB_CANGA
Sequence: MFMLRVSRRGLATATSVPRLKTFKIYRWNPDKPTEKPHLQEYKVDLEDCGPMVLDALLKIKNEQDATLTFRRSCREGICGSCAMNIGGANTLACLCKIDQDESKTTKIYPLPHMFIVKDLVPDLTGFYQQYKSIQPYLQRTDYPADGKEVLQSIDDRKKLDGLYECILCACCSTSCPSYWWNQEEYLGPAVLMQAYRWLIDSRDQATKARRTMLQNSMSLYRCHTIMNCTRTCPKGLNPGRSIAEIKKQLAFD
What is the function of this protein?
Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
What are the official names of this protein?
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial, Iron-sulfur subunit of complex II, Ip.
What is the protein family that this protein belongs to?
Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: YBEY_MYCGE
Sequence: MKSSFSINSSRLFKRFFGKNYQAGVELCFQIIKSSLNLSFDPEFALLIVSCSKMKKLNKQFLKRRGCTDVISLCYNETETGFSLAIGEIFLCPKYIFKKAKEIGCNNWFLLTRCLIHGILHLFEFNHEESEAFESVTMFFQDAIHEEILSVWKF
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLIM_ASPFU
Sequence: MAPGLLENNTLSGTAAPRTEFKAIVNDLRELQAHVQRVQSAIEAPEVQSWLNEQLHHPDQLPDKELEQLALDLVDSMDKLQLQLVPSVSLLTDGFFGYLNSKTLWTVVEAQVADRLAENGPQPVSTLGLRCGIQPERLAQLLDTLVSNGIFAYNPADDTYSNNRASLLLCHDHWTQWHLWADLYPNEFFDVSRAMPQAVRLGESRTAAQIAYGTDLDLFEYLAKEQKLAKFQKTLGAGAVAQARGLTVDYPWEEIGSEPILDIGGGSGAFLASLLRAHPHLRGSLMDIQSVIELITPEFREPHGRFSDIGSRVQQLVVGDFTKQIPPSAVYTMKWCLHDWVDDDVLTILKNVRRSIVPSSVSRFLVVESIKSPGRSGRLPRYGDLIMMITCNGKERSLEDWKRLGELAGWKLYQVHRVRRAWPCIIDFRPM
What is the function of this protein?
O-methyltransferase; part of the gene cluster that mediates the biosynthesis of gliotoxin, a member of the epipolythiodioxopiperazine (ETP) class of toxins characterized by a disulfide bridged cyclic dipeptide (PubMed:15979823, PubMed:21612254).  The first step in gliotoxin biosynthesis is the condensation of serine and phenylalanine to form the cyclo-L-phenylalanyl-L-serine diketopiperazine (DKP) by the NRPS gliP (PubMed:17154540, PubMed:21612254).  GliP is also able to produce the DKP cyclo-L-tryptophanyl-L-serine, suggesting that the substrate specificity of the first adenylation (A) domain in gliP is sufficiently relaxed to accommodate both L-Phe and L-Trp (PubMed:23434416).  The cytochrome P450 monooxygenase gliC has been shown to catalyze the subsequent hydroxylation of the alpha-carbon of L-Phe in cyclo-L-phenylalanyl-L-serine whereas the second cytochrome P450 enzyme, gliF, is presumably involved in the modification of the DKP side chain (PubMed:24039048, PubMed:23434416).  The glutathione S-transferase (GST) gliG then forms a bis-glutathionylated biosynthetic intermediate which is responsible for the sulfurization of gliotoxin (PubMed:21513890, PubMed:21749092).  This bis-glutathionylated intermediate is subsequently processed by the gamma-glutamyl cyclotransferase gliK to remove both gamma-glutamyl moieties (PubMed:22903976, PubMed:24039048).  Subsequent processing via gliI yields a biosynthetic intermediate, which is N-methylated via the N-methyltransferase gliN, before the gliotoxin oxidoreductase gliT-mediated disulfide bridge closure (PubMed:20548963, PubMed:22936680, PubMed:24039048, PubMed:25062268).  GliN-mediated amide methylation confers stability to ETP, damping the spontaneous formation of tri- and tetrasulfides (PubMed:25062268).  Intracellular dithiol gliotoxin oxidized by gliT is subsequently effluxed by gliA (PubMed:26150413).  Gliotoxin contributes to pathogenesis during invasive aspergillosis (PubMed:17601876, PubMed:18199036).  In macrophages and neutrophils, gliotoxin showed inhibition of various different cell functions including cytokine production, antigen presentation, phagocytosis, and production of reactive oxygen species (PubMed:17601876).
What are the official names of this protein?
O-methyltransferase gliM, Gliotoxin biosynthesis protein M.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. COMT subfamily.
Protein: PHOU_ZYMMO
Sequence: MKKASEIGHTVKAFDEDLGGLRALICEMGGLTEIALTSTLEALIHSNKELAAQIVEKDKEIDALEIEAERVAMRIISLRAPLADDLRDVIAAMKISGILERMADYAKNIAKRVPILQNMVSIHPVPVLPVMGEMVSEMVRNVLDAYAARDPKKALHVAEYDMEVDGLYNNLFRILLTYMMEDSGRISTCIHLMFIAKNLERIGDHATNIAEMVYFAATGKQMPERTRGKDLLASEGS
What is the function of this protein?
Plays a role in the regulation of phosphate uptake.
What are the official names of this protein?
Phosphate-specific transport system accessory protein PhoU homolog, Pst system accessory protein PhoU homolog.
What is the protein family that this protein belongs to?
Belongs to the PhoU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KHSE_ECO7I
Sequence: MVKVYAPASSANMSVGFDVLGAAVTPVDGALLGDVVTVEAAETFSLNNLGRFADKLPSEPRENIVYQCWERFCQELGKQIPVAMTLEKNMPIGSGLGSSACSVVAALMAMNEHCGKPLNDTRLLALMGELEGRISGSIHYDNVAPCFLGGMQLMIEENDIISQQVPGFDEWLWVLAYPGIKVSTAEARAILPAQYRRQDCIAHGRHLAGFIHACYSRQPELAAKLMKDVIAEPYRERLLPGFRQARQAVAEIGAVASGISGSGPTLFALCDKPDTAQRVADWLGKNYLQNQEGFVHICRLDTAGARVLEN
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AAPAT_RICPR
Sequence: MSIISTRLNSIKPSPTLAVVKKTLELKKAGVNIIALGAGEPDFDTPDNIKEVAITSIKDGFTKYTNVDGIPLLKQAIKNKFKRENNIDYELDEIIVSTGGKQVIYNLFMASLDKGDEVIIPVPYWVSYPDMVALSTGTPVFVNCGIENNFKLSVEALEHSITDKTKWLIINSPSNPTGAGYNCKELENIAKTLRKYPNVNIMSDDIYEHITFDDFKFYTLAQIAPDLKERIFTVNGVSKAYSMTGWRIGYGAGSKALIKAMTIIQSQSTSNPCSISQMAAIEALNGTQDYIKSNALNFQKKRDLALSILEEVTYFECYKPEGAFYLFVKCDKIFGTKTKSGRIIANSNNFSEYLLEEAKVAVVPGIAFGLDGYFRISYATSMQELEEACIRIKHACNAL
What is the function of this protein?
Catalyzes the reversible conversion of aspartate and 2-oxoglutarate to glutamate and oxaloacetate.  Can also transaminate prephenate in the presence of glutamate.
What are the official names of this protein?
Probable aspartate/prephenate aminotransferase, AspAT / PAT, Transaminase A.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CS2H_ACIS1
Sequence: MVSEYIDSELKRLEDYALRRVKGIPNNRRLWVLTCMDERVHIEQSLGIQPDDAHIYRNAGGIVTDDAIRSASLTTNFFGTKEIIVVTHTDCGMLRFTGEEVAKYFISKGIKPTEVQLDPLLPAFRISSEEDFIKWFKFYEDLGVKSPDEMALKGVEILRNHPLIPKDVRITGYVYEVETHRLRKPNQIIYNETSKFEHGTIVKE
What is the function of this protein?
Catalyzes the conversion of carbon disulfide into hydrogen sulfide and carbon dioxide, with carbonyl sulfide as an intermediate.  Likely plays a key role in sulfur metabolism that allows Acidianus sp.  A1-3 to grow on carbon disulfide as the main carbon and energy source.  Does not show carbonic anhydrase activity (hydration of CO(2) to carbonate).
What are the official names of this protein?
Carbon disulfide hydrolase, CS(2) hydrolase, Carbon disulfide lyase.
What is the protein family that this protein belongs to?
Belongs to the beta-class carbonic anhydrase family.
Protein: V5NTD_GLOBR
Sequence: MQTPKRRRGAQGCPRSSPSPPLLLLVGAVWFCAALSVAAGSFELTILHTNDVHARVEQTSRDSGKCTGQDCYGGVARRATKIRELRANHSHVLLLDAGDQYQGTIWFSFFKGREVVKFMNSLGYDAMALGNHEFDNGLAGLLDPLLKHANFPILSANIRPKGSIASNISGYILPYKIINVGSEKVGIIGYTTKETPVLSNPGPYLEFRDEVEELQKHANKLTTLGVNKIIALGHSGFFEDQRIARKVKGVDVVVGGHTNTFLYTGSPPSTEVAAGNYPFMVKSDDGRQVPVVQAYAFGKYLGYLNVIFDDKGNVIKSSGNPILLNKNISEDQDVKAEVNKMKIQLHNYSSQEIGKTIVYLNGTTQACRFHECNLGNLICDAVIYNNVRHPDYNEWNHVSMCIVNGGGIRSPIDERANNGTITLEELTAVLPFGGTFDLLQIKGCALKQAFEHSVHRHGQGMGELLQVSGIKVVYDLSRKPGSRVVSLNVLCTECRVPTYVPLEKEKTYKLLLPSFLAGGGDGYHMLKGDSSNHSSGNLDISIVGDYIKRMGKVFPAVEGRVIFSAGTLFQAQLFLTWGLCISLLYFIL
What is the function of this protein?
Hydrolyzes nucleotides into nucleosides (By similarity).  Snake venom 5'-nucleotidases are widely distributed among venomous snake taxa, but there is a lack of information about their biological activities.  They have been shown to inhibit platelet aggregation.  This effect may be due to the liberation of inhibitory AMP or adenosine by its action on ADP released upon initiation of aggregation.  Venom 5'-nucleotidases are also known to synergistically act in vivo with other toxins like ADPases, phospholipases, and disintegrins to exert a more pronounced anti-coagulant effect.
What are the official names of this protein?
Snake venom 5'-nucleotidase, 5'-NT, Ecto-5'-nucleotidase.
What is the protein family that this protein belongs to?
Belongs to the 5'-nucleotidase family.
What are the subcellular locations of this protein?
Membrane; Lipid- anchor, GPI-anchor.
Protein: UBIE_YERE8
Sequence: MVDQEKETTHFGFRTVAKEQKEGMVAEVFHSVAAKYDLMNDLMSFGVHRIWKRFTIDCSGVRRGQRVLDLAGGTGDLTAKFSRLVGEQGEVVLADINESMLRMGREKLRDKGIVGNVSYVQANAEALPFPDNYFDCITISFGLRNVTEKEKALRSMFRVLKPGGRLLVLEFSKPLLEPLSKAYDAYSFHILPKIGELVAQDSESYRYLAESIRMHPDQETLKSMMMDAGFENVTYSNLTGGIVALHRGFKF
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: ATPL_THEP1
Sequence: MENLGDLAQGLALLGKYLGAGLCMGIGAIGPGIGEGNIGAHAMDAMARQPEMVGTITTRMLLADAVAETTGIYSLLIAFMILLVV
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CHAD_HUMAN
Sequence: MVRPMLLLSLGLLAGLLPALAACPQNCHCHSDLQHVICDKVGLQKIPKVSEKTKLLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQLPSNFPFDSLETLALTNNPWKCTCQLRGLRRWLEAKASRPDATCASPAKFKGQHIRDTDAFRSCKFPTKRSKKAGRH
What is the function of this protein?
Promotes attachment of chondrocytes, fibroblasts, and osteoblasts.  This binding is mediated (at least for chondrocytes and fibroblasts) by the integrin alpha(2)beta(1).  May play an important role in the regulation of chondrocyte growth and proliferation (By similarity).
What are the official names of this protein?
Chondroadherin, Cartilage leucine-rich protein.
What is the protein family that this protein belongs to?
Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class IV subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: Y2331_ARCFU
Sequence: MPAYVFSKESFLKFLEGHLEDDVVVVVSSDVTDFCKKLSESMVGEKEYCFAEFAFPADIFDADEDEIDEMMKYAIVFVEKEKLSEAGRNAIR
What are the official names of this protein?
Uncharacterized protein AF_2331.
Protein: TYRA_ENTAG
Sequence: MVAELTALRDQIDSVDKALLDLLAKRLELVAEVGEVKSRYGLPIYVPEREASMLASRRKEAEALGVPPDLIEDVLRRVMRESYTSENDKGFKTLCPELRPVVIVGGKGQMGRLFEKMLGLSGYTVKTLDKEDWPQAETLLSDAGMVIISVPIHLTEQVIAQLPPLPEDCILVDLASVKNRPLQAMLAAHNGPVLGLHPMFGPDSGSLAKQVVVWCDGRQPEAYQWFLEQIQVWGARLHRISAVEHDQNMAFIQALRHFATFAYGLHLAEENVNLDQLLALSSPIYRLELAMVGRLFAQDPQLYADIIMSSESNLALIKRYYQRFGEAIALLEQGDKQAFIASFNRVEQWFGDHAKRFLVESRSLLRSANDSRP
What are the official names of this protein?
T-protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the prephenate/arogenate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCTA_BURM7
Sequence: MKKPFYKVLYVQVIFAIVVGVILGHYYPSLAVDMKPLGDGFIKLIKMVIGPIIFCTVVTGIAGMQDMKKVGRVGGKALLYFEIVSTCALVLGLAATHILRPGVGFNIDPATLNGKEVASYAAKAHGQSSVDFLMHIIPNTMIDAFAQGEILQILLIALLFGSVLAHLGERGRVVTDFIDGITRVLFGIVHIVTKLAPIGAFGAMAFTIGKYGVGSLVPLLKLIGTFYLTSVVFVLVVLGAIARFTGFSIIRFVGYIKEELLIVLGTSSSEAALPQLMEKLEKAGCSRSVVGLVVPTGYLFNLDGTNIYMTMAVLFIAQATNIELTWMQQLTLLAVAMLTSKGASGVTGAGFITLAATLAVVPTIPLSGMVLILGIDRFMSECRALTNIVGNGVATVVVSAWEKELDRAKLRAALSGNGEAAAGEAARV
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RPOC_MYCA9
Sequence: MLDVNFFDELRIGLASADDIRNWSFGEVKKPETINYRTLKPEKDGLFCEKIFGPTRDWECYCGKYKRVRFKGIICERCGVEVTRAKVRRERMGHIELAAPVTHIWYFKGVPSRLGYLLDLAPKDLEKIIYFAAYVITAVDDELRHNELSTLEAEMEVEKKAVADQRDADLEARAQKLEADLAELEAEGAKSDVRRKVRDGGEREMRQLRDRSQRELDRLDEIWTTFTKLAPKQLIVDEVLYRELVDRYGEYFTGAMGAEAVQKLIQNFDLDAEAENLRETIRSGKGQKKLRALKRLKVVAAFQNSTNSPGGMVLDAVPVIPPELRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLIDLGAPEIIVNNEKRMLQESVDALFDNGRRGRPVTGPGNRPLKSLSDLLKGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKLMALELFKPFVMKRLVDLNHAQNIKSAKRMVERQRAQVWDVLEEVIAEHPVLLNRAPTLHRLGIQAFEPQLVEGKAIQLHPLVCEAFNADFDGDQMAVHLPLSAEAQAEARILMLSSNNILSPASGRPLAMPRLDMVTGLYFLTTEIPGDIGAHAPAGKDQPEVGVYSSPAEAIMAMDRGALSVRAPIRVRLTQQRPPAEVEAELFENGWQPGDAWVAETTLGRVLFNELLPHGYPFVNKQMHKKVQSAIINDLAERFPMIVVAQTVDKLKDAGFHWATRSGVTVSMADVLVPPQKAEILDRYEKEAERIEKQYQRGALNQQERRDALVKIWQEATDEVGKALEEHYPADNPITLLPKSGATGNMTQVRNLAGMKGLVTNPKGEYIPRPIKSSFREGLTVLEYFINTHGARKGLADTALRTADSGYLTRRLVDVSQDVIVREHDCGTERGINVVIAEKQTGPDGKATLIRDAHIETSAYARTLAADAVDADGNVLVERGHDLGDPAIEKLLAAGVTTVKVRSVLTCTTGTGVCAMCYGRSMATGKLVDIGEAAGIVAAQSIGEPGTQLTMRTFHQGGVGDDITGGLPRVTELFEARVPKGKAPIADVTGRVRLEEGERFYKITIVPDDGGEEVVYDKLSKRQRLRVFKHEDGSERPLADGDHVEVGQQLMEGAADPHEVLRVMGPRQVQVHLVNEVQEVYRSQGVSIHDKHIEVIVRQMLRRVTIIDSGATEFLPGSLTERAEFESENRRVVAEGGEPAAGRPVLMGITKASLATDSWLSAASFQETTRVLTDAAINCRSDKLNGLKENVIIGKLIPAGTGINRYRNISVQPTEEARAAAYTIPSYEDQYYSPDFGSNTGAAVPLDDYGYSDYR
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: BIND_MESFR
Sequence: MGFHQISVIIVVLALASARAADEFPSHTDTPTDCPEADHGCWCHGSFAQCWRTYEDSRMTEEIGNRITQLELLYQPSEEVVTYIRRISALRELRISEDGMSLDCSCDVIYALDDKQVTLVNQAELTFGNCRERGWPRERMAARPFVHRCHVLRMQDGETRKRRGADDNDGDDVSKRASPRKGDEPAGHKLKDLAPQNTHHLVNIHDADKHPASEFVNFISGHRRSRRSTDDDAAVSDDSERGARKKRYGNQGNYPQAMNPQSRGVNYGQPAQQGYGAQGMGGAFGGGQGMGGAVRGGQGMGGAVGGGQFGAFSPGEAEADNADYDEYSDSLDEGDTTISAAVMDDIKAVLGATKIDLPVDINDPYDLGLLLRHLRHHSNLLANIGDPAVREQVLSAMQEEEEEEEEDAANGVRQNVLNNINANAPGNAGYGGQGGMGAFGGGGGGMGAIGGGGGAMMGQQGMGGVPQRMGGQPQGNAYNQGYRQG
What is the function of this protein?
Species-specific sea urchin sperm protein required for adhesion of sperm to the egg surface during fertilization.  Bindin coats the acrosomal process after it is externalized by the acrosome reaction.  It binds to sulfated, fucose-containing polysaccharides on the vitelline layer receptor proteoglycans which cover the egg plasma membrane.
What are the official names of this protein?
Bindin.
What is the protein family that this protein belongs to?
Belongs to the bindin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, acrosome lumen.
Protein: RSMA_METFK
Sequence: MKHVAKKRFGQNFLTDRAIINSLIDAIAPQPQDCMVEIGPGLGAMTQPLLERLQHLHVVEIDRDIIQWMQGHYPQDKLTIYASDALKFNFGNISDRLRVVGNLPYNISTPILFHLLDNVPHIIDMHFMLQKEVVERMVAAPSSAAYGRLSVMLQYRLHMEYLLTVPPEAFDPAPKVESAFVRAVPYTVLPHPAKDEALLGRIVTAAFAQRRKTLRNTLKGLLDDTGFASLGIDPQLRAENIAPAGFVAIANYLAA
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAN1_NEOFI
Sequence: MYSSSNSFLGGVNNARPGQPPFMQQPPYSQFPQGQQQIPQQTGFQPQPAGYGPQSASHLQPQPTGFPTGQLQPQFTGFPGAAPQQQQQQLGGYQAPAQQPQFTGYPPQSQPPSLQVPSTTGLPTRLAPRTSSEIANSFSDGAGVAPPPPPKSSGSKIPNIRLSFITAQDQAKFEQLFKSAVGDSQTMDGEKAKELLLRSRLPGSELSKIWVLSDTTKSGQLFFPEFALAMYLCNLRITGRELPATLPDKIKNEVSSMVDIISFGVPDTEPQASARTNVPSFDAPLLENKSAPPAPQHPKPQQPSNAQFLSQLAAQPTGFGPQATGLQPNQPSLLGANAALAPQATGFPGQSQQQYLQPQPTGLMTNPQATGYNGPRPPLPPMPTGFGSNLSSMQTGGLVAQPTGIPGQWGFVNAPSSGLPNIEALKQQLMPQPGREGGFTTAGLSGNASIPWAITKEEKKIYDDLFRAWDGFHKGFIGGDTAIEIMGQSGLDRKDLERIWTLADPNNRGRLNMDEFAVAMHLIYRKLNGYPVPNRLPPELIPPSTRNLNDSIGAVKSLLSQDAENRKASGAFLQPQKTGVSYLKEHSFRGGARSPGFGRKDATLFKNNDEAAAGYRSSARRRMGNDARPSSPAASQASEEELSVEQLKKKIRETQIMLDAVDFNDENRAEEDEVLDRRDRLEAESLMDRTRRVQDDIDTHPNAAFRNLDNGAERRALRRQLQAFEDQVPQVASEVRRIEREIADAKLELFRLKDAKAHPNSAANIVGTGPGGTVTEADRIKARARARMQARAAELAGRPVPASVDDDGAAARRLEAESTSIRADREKNEAMTRDVEESVREFTRSLEDSLKEEGETSTREHERRRWEDALGVEDVIRDFIYDLQRGSRTAHVRKEEESRASEQRLRHEEPSAGVSRLSPAPSAGSAGSLPGSTHEDRVAAARERAQRRIAERMAAAGLKPHTDTSETLLQRQEREKREREERLRQAEEEDAKREQERQRRLAEEQRSTSNAPAKPVGKKPPPAPPSRRGRTDSAGQAEVKKAAEETVTAEQAAREQAIREEQQAQEEETNRLEMEAQQREEELLKEKEAQEARLRALEEQVRQGKIRKQEEKRRKEEAERLAKEKEAALAAQRAEIERAKERERQLQLELEGLDEESSSDDEGPANITPEDSTPTQSQLLPTVTPAAPVSAPESEQAGSPEDTSSQAPPVGFSSETESKNPYFKITHQAADTQVVSPPPAPQPNVTSPRADVHSTNPFHRLAQQESSKPVFTGSAPLERKSRARPEADDDWSAAGSEFDSSDDDDDERPGGGSAKQLASILFGTMAPPRPLSAMDDKSPSKSSTPVQDSPVTSLPVPEPNGSLSAPAAPPPPPPPPPPAAVPSYDSSVAPPPPPAPPMAPPMAPPAPPPGPPPPPGPPPPPAPPAAGGPPTPAGAPDRSALLASIQMGKGLRKVQTNDRSTSSSAGRVLD
What is the function of this protein?
Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis.  The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton.  Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins.  Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity).
What are the official names of this protein?
Actin cytoskeleton-regulatory complex protein pan1.
What is the protein family that this protein belongs to?
Belongs to the PAN1 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, actin patch. Note=Cytoplasmic and cortical actin patches.
Protein: MAD14_ORYSI
Sequence: MGRGKVQLKRIENTINRQVTFSKRRSGLLKKANEISVLCDAEVALIIFSTKGKLYKYATDSCMDKILERYERYSYAEKVLISAESDTQGNWCHEYRKLKAKVETIQKCQKHLMGEDLESLNLKELQQLEQQLENSLKHIRSRKSQLMLESINELQRKEKSLQEENKVLQKELVEKQKVQKQQVQWDQTQPQTSSSSSSFMMREALPTTNISNYPAAAGERIEDVAAGQPQHVRIGLPPWMLSHING
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
MADS-box transcription factor 14, FDRMADS6, OsMADS14, Protein AGAMOUS-like 10, Protein APETALA1-like B, RMADS211.
What are the subcellular locations of this protein?
Nucleus.
Protein: PDRP2_LISW6
Sequence: MEKSVIIYVISDAIGETAQHIIRAVTAQFSLNKPADIRRHAFIRDEKALLETLEEAKAADGIVVQTLVQSPLAEYATDFCAQNNIPNIDLLHTLTAAVEAKTGLKSKQDPGNMRRLDSNYFDRIAAIEFAVKYDDCKDPRGLIDADIVLVGVSRTSKTPLSSFLANQNWKVANVPLVPEIPIPDELFQIPNERIIGLTTTPEKLAQIRKVRLKSIGLDESSSYSSEKRILEELEYGYDTFKKLGCQVIHVEDKAIEETAALITEIITSYH
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein 2, PPDK regulatory protein 2.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: MRAZ_STAA2
Sequence: MFMGEYDHQLDTKGRMIIPSKFRYDLNERFIITRGLDKCLFGYTLDEWQQIEEKMKTLPMTKKDARKFMRMFFSGAVEVELDKQGRINIPQNLRKYANLTKECTVIGVSNRIEIWDRETWNDFYEESEESFEDIAEDLIDFDF
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RS12_RALPJ
Sequence: MPTINQLVRKPRVSEKLKSKSPALENCPQRRGVCTRVYTTTPKKPNSALRKVAKVRLTNGFEVISYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGSLDLQGVKDRKQARSKYGAKRPKAA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: UNG_CHRVO
Sequence: MTYLAPALARIHPDWEAVLDQAAVAARLAEIDRLLVLQQQDGKTLFPPPPQVFNALAFAAPADVKVVILGQDPYHGDGEAMGLSFSVPDGARVPPSLRNIYKELAADLGLGVPASGDLTHWAQQGVLLLNSVLTVERDKAGSHGKLGWQTVSDALIDAVNRDNPGCVFLLWGNWAQTKAERIDASRHLVLTAAHPSPLSASRGFHGCRHFSQVNAWLIARGRQPVRWATAPAAQSCLF
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CA11_CONCB
Sequence: MGMRMMFTVFLLVVLATTVVSFTSDRASDGRNAAANAFDLIALIARQNCCSIPSCWEKYKCS
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.
What are the official names of this protein?
Alpha-conotoxin-like Ca1.1.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ERH_PIG
Sequence: RADTQTYQPYNKDWIKEKIYVLLRRQAQQAGK
What is the function of this protein?
AP 3910 has antibacterial activity against B. megaterium.
What are the official names of this protein?
Enhancer of rudimentary homolog.
What is the protein family that this protein belongs to?
Belongs to the E(R) family.
What are the subcellular locations of this protein?
Nucleus.