PharMolix/UniProtQA huggingface dataset:
Protein: SYK_RICCK
Sequence: MLEIWEDAIQSNAWPFVEAKKILDSLNGKTPEKGYILFETGYGPSGLPHIGTFGENARMVMVQKAFEQLSSIPTKLICFSDDMDGLRKVPSNIPNSEMLAQYMDMPLTSILDPFGEYESYGAYMNAKLRSFLDKFGFEYEFYSSTKCYKAGMFDEMLLKVLEKYDEIMELMLPTFREERKATYSPFMPICPKTGKVLQVPIEKWDAKRGTVTYKDEDNNYIEVPVTGGHCKLQWKPDFGMRWAALKVDYEMYGKDHLANARLYSEICRILGGKPPVQLCYELFLDENGEKISKSKGNSISVDDWLKYAPVESMALFMYQNPTRAKRLFFDVIPQNVDAYITFNQKYHLEEDRAKRFANPVYHIHHGHVPKIETFGITYSLLLNLTSVCNPSDKSVLWGFISKYAPKATPNTTTYLDRLAEFAIRYYDDFIKAHKSYYTPSEKHKVILRDILDMLSSISEETEGEVIQKSIYDIGMKAGYENLRDYFKDLYQILLGQNEGPRLGTFIKLYGIKEMKKLIERKL
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NGEF_RAT
Sequence: METKNSEDQGKPQRKSVSSLWKSKHGPAEMRPELPPETAKETQNEEPRCLIPIQRNSLFNRAMRHKHKARSMSERRANDQAGDLPETRKSVNEPLAFNLPQGRLPPWRTPAQRGPGAQEASESSSTPGNGTTPEECPALTDSPTTLTEALQMIHPIPADSWRNLIEQIGLLYQEYRDKSTLQEIETRRQQDAEIQGNSDGSQAGEDNAEEEEEEEEEPASPPERRALPQICLLSNPHSRFNLWQDLPEIQSSGVLDILQPEETKLQEAMFELVTSEASYYKSLNLLVSHFMENERLKKILHPSEAHILFSNVLDVMAVSERFLLELEHRMEENIVISDVCDIVYRYAADHFSVYITYVSNQTYQERTYKQLLQEKTAFRELIAQLELDPKCKGLPLSSFLILPFQRITRLKLLVQNILKRVEEGSEREGTALDAHKELEMVVKACNEGVRKMSRTEQMISIQKKMEFKIKSVPIISHSRWLLKQGELQQMSGPKTSRTLRTKKLFREIYLFLFNDLLVICRQIPGDKYQVFDSAPRGLLRVEELEDQGQTLANVFILRLLENADDREATYMLKASSQSEMKRWMTSLAPNRRTKFVSFTSRLLDCPQVQCVHPYVAQQPDELTLELADILNILEKTEDGWIFGERLHDQERGWFPSSMTEEILNPKIRSQNLKECFRVHKMEDPQRSQNKDRRKLGSRNRQ
What is the function of this protein?
Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42.  Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis.  Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation.  Activated RHOA promotes cone retraction at the expense of RAC1- and CDC42-stimulated growth cone extension.
What are the official names of this protein?
Ephexin-1, Eph-interacting exchange protein, Neuronal guanine nucleotide exchange factor.
What are the subcellular locations of this protein?
Cytoplasm. Membrane. Cell projection, growth cone. Note=Associated with membranes. Localizes to axonal growth cones.
Protein: GMHBA_MYCTO
Sequence: MVAERAGHQWCLFLDRDGVINRQVVGDYVRNWRQFEWLPGAARALKKLRAWAPYIVVVTNQQGVGAGLMSAVDVMVIHRHLQMQLASDGVLIDGFQVCPHHRSQRCGCRKPRPGLVLDWLGRHPDSEPLLSIVVGDSLSDLELAHNVAAAAGACASVQIGGASSGGVADASFDSLWEFAVAVGHARGERG
What is the function of this protein?
Converts the D-glycero-alpha-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-alpha-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position.
What are the official names of this protein?
D-glycero-alpha-D-manno-heptose-1,7-bisphosphate 7-phosphatase, D,D-heptose 1,7-bisphosphate phosphatase, HBP phosphatase.
What is the protein family that this protein belongs to?
Belongs to the GmhB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL37A_NANEQ
Sequence: MAFSHTKKVGPTGRFGPRYGLGIRKRVLTVEIKQRKKHVCPFCRSKAVIREAYGIYRCKKCGKQFTGLAYYPYEHLHEYYKIRGGQ
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L37Ae, Ribosomal protein L43e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily.
Protein: NUOC_BORPA
Sequence: MSRFTYAYMMMTRLETLKNNLQAAFGQDLALTESLGELTLEVAAEQWFSACTKLRTDPALRFESCIDLCGVDYLTWGNGTQPEEKTGPVTHGRYAVVVHLLSIEHNWRLRVRTWAPDDEFPMVSSLLECWPGVNWFEREAFDLYGIVFEGHPDLRRILTDYGFIGHPFRKDFPLSGTVEMRYDPEQKRVIYQPVTIDPREITPRVVREGSYGMGR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: BTUF_ECOL6
Sequence: MAKSLFRALVALSFLAPLWLNAAPRVITLSPANTELAFAAGITPVGVSSYSDYPLQAQKIEQVSTWQGMNLERIVALKPDLVIAWRGGNAERQVDQLASLGIKVMWVDATSIEQIANALRQLAPWSPQPDKAEQAAQSLLDQYAQLKAQYADKPKKRVFLQFGINPPFTSGKESIQNQVLEVCGGENIFKDSRVPWPQVSREQVLARSPQAIVITGGPDQIPKIKQYWGEQLKIPVIPLTSDWFERASPRIILAAQQLCNALSQVD
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Binds vitamin B12 and delivers it to the periplasmic surface of BtuC.
What are the official names of this protein?
Vitamin B12-binding protein.
What is the protein family that this protein belongs to?
Belongs to the BtuF family.
What are the subcellular locations of this protein?
Periplasm.
Protein: ARNF_SALAR
Sequence: MGVMWGLISVAIASLAQLSLGFSMMRLPSIAHPLAFIAGLGAFTTATLALFAGLAGYLIPVSCWQKTLHSLALSKTYALLSLSYVLVRVVTRSVRRFLSKSDARRIVHCGGDNADFPARQLMMACASTAAIRRRNNIEH
What is the function of this protein?
Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
What are the official names of this protein?
Putative 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF, L-Ara4N-phosphoundecaprenol flippase subunit ArnF, Undecaprenyl phosphate-aminoarabinose flippase subunit ArnF.
What is the protein family that this protein belongs to?
Belongs to the ArnF family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS7_ACISJ
Sequence: MTSSALVPSSAELCPDRTAEVSRTTAETRITVRVNLDGTGAASLHTGIGFFDHMLDQIARHGLIDLQIDCDGDLHIDGHHTVEDVGITLGQAFARAVGDKKGIRRYGHAYVPLDEALSRVVVDFSGRPGLHLHIPFTAGSIGGFDTQLTYEFFQGFVNHAGVTLHIDNLKGINAHHQCETVFKAFARALRAALERDPRAAGVIPSTKGSL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOI_DINSH
Sequence: MAQMDYTRAAKYFLLFDFFAGFKLGLKYFFKPKATLAYPHEKGPLSPRFRGEHALRRYPNGEERCIACKLCEAICPAQAITIDAEPRDDGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFATETREELFYDKEKLLDNGERWEAEIARNLELDAPYR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ERA_LISMH
Sequence: MSEPFKSGFVAIVGRPNVGKSTLLNHIIGQKIAIMSDKAQTTRNKVQGVYTTDESQIIFIDTPGIHKPKHKLGDFMVKIALNTFQEVDLIYFVIDASTGFGRGDEFIIEKLKNVQTPVFLLINKIDLIAPEDLFKLIEQYRDLMEFDEIIPISALQGNNVPNLLEQTNANLEIGPMYYPKDQITDHPERFIISELIREQVLQLTREEVPHSVAVVIEGIEKNPKTEKLTINATIIVERSTQKGIIIGKQGQMLKQIGMRARKEIERLLGSKVFLEVWVKVQKNWRDKEHYLQDYGFDREEY
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: DENR_HUMAN
Sequence: MAADISESSGADCKGDPRNSAKLDADYPLRVLYCGVCSLPTEYCEYMPDVAKCRQWLEKNFPNEFAKLTVENSPKQEAGISEGQGTAGEEEEKKKQKRGGRGQIKQKKKTVPQKVTIAKIPRAKKKYVTRVCGLATFEIDLKEAQRFFAQKFSCGASVTGEDEIIIQGDFTDDIIDVIQEKWPEVDDDSIEDLGEVKK
What is the function of this protein?
May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon.  Involved in translation initiation; promotes recruitmnet of aminoacetyled initiator tRNA to P site of 40S ribosomes.  Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits.  Plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1.
What are the official names of this protein?
Density-regulated protein, DRP, Protein DRP1, Smooth muscle cell-associated protein 3, SMAP-3.
What is the protein family that this protein belongs to?
Belongs to the DENR family.
Protein: DUT_SHESA
Sequence: MKTPIELKILDSRIGSEFPLPAYATPGSAGMDLRAMIDTTMTIAPGETQLIPTGIAIHVADPGLAAVILPRSGLGHKHGIVLGNLVGLIDSDYQGPLMVSCWNRSDTPFTLEIGDRLAQLVFVPVVQAQFKLVDEFDSSDRGEGGFGHSGTK
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: Y2735_LYSSC
Sequence: MMKKSFYLYVLTFRGGDWSDPKVRFAEEMFHEHNFPKQSTDFNELSNYIESYATENLTIEAFDHLWELYEGQA
What are the official names of this protein?
UPF0346 protein Bsph_2735.
What is the protein family that this protein belongs to?
Belongs to the UPF0346 family.
Protein: CARB_STAAB
Sequence: MPKRNDIKTILVIGSGPIIIGQAAEFDYAGTQACLALKEEGYRVILVNSNPATIMTDKEIADKVYIEPLTHDFIARIIRKEQPDALLPTLGGQTGLNMAIQLHESGVLQDNNVQLLGTELTSIQQAEDREMFRTLMNYLNVPVPESDIVNTVEQAFKFKEQVGYPLIVRPAFTMGGTGGGICHNDEELHEIVSNGLHYSPATQCLLEKSIAGFKEIEYEVMRDKNDNAIVVCNMENIDPVGIHTGDSIVVAPSQTLSDVEYQMLRDVSLKVIRALGIEGGCNVQLALDPHSFDYYIIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEMLNPITGTSYATFEPTLDYVISKIPRFPFDKFEKGERELGTQMKATGEVMAIGRTYEESLLKAIRSLEYGVHHLGLPNGESFDLDYIKERISHQDDERLFFIGEAIRRGTTLEEIHNMTQIDYFFLHKFQNIIDIEHQLKEHQGDLEYLKYAKDYGFSDKTIAHRFNMTEEEVYQLRMENDIKPVYKMVDTCAAEFESSTPYYYGTYETENESIITDKEKILVLGSGPIRIGQGVEFDYATVHAVWAIQKAGYEAIIVNNNPETVSTDFSISDKLYFEPLTEEDVMNIINLEKPKGVVVQFGGQTAINLADKLAKHGVKILGTSLENLNRAEDRKEFEALLRKINVPQPQGKTATSPEEALANAAEIGYPVVVRPSYVLGGRAMEIVDNDKELENYMTQAVKASPEHPVLVDRYLTGKEIEVDAICDGETVIIPGIMEHIERAGVHSGDSIAVYPPQTLTEDELTTLEDYTIKLAKGLNIIGLINIQFVIAHDGVYVLEVNPRSSRTVPFLSKITDIPMAQLAMRAIIGEKLTDMGYQEGVQPYAEGVFVKAPVFSFNKLKNVDITLGPEMKSTGEVMGKDTTLEKALFKGLTGSGVEVKDHGTVLMTVSDKDKEEVVKLAQRLNEVGYKILATSGTANKLAEYDIPAEVVGKIGGENDLLTRIQNGDVQIVINTMTKGKEVERDGFQIRRTTVENGIPCLTSLDTANALTNVIESMTFTMRQM
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: PETN_AMBTC
Sequence: MDIVSLAWAALMVVFTFSLSLVVWGRSGL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 8, Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PetN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: SFH5_PICST
Sequence: MSEPEKTDSVETVKNTIKSTQLTTEHAKKLTQVVNSIPTILSKLDNSEYDEIFGHRINVDSKKFVDVAVRNEILLKFLAADEYDVELATKRLIDTLNWRNKFHPLSAAFDENFNKALNDLGAITNFVGLKSDNLNVVTWNFYGATTPKKLFEEYGDNAGTTTNQRPGSQFLRWRIGLMEKSLQLVDFTDPKNNKIAQVHDYNNVSMFKVDKGMRAATKEIIKIFGDNYPELLSTKFFINVPSLMSWVFTFFKTIGVISEATLKKFQVLNSGNLTEWFGKSNLPPTYGGDSKSSMKELNVASIKLSPYGEYILEELGKKEIEDVIDEVE
What is the function of this protein?
Non-classical phosphatidylinositol (PtdIns) transfer protein (PITP), which exhibits PtdIns-binding/transfer activity in the absence of detectable PtdCho-binding/transfer activity.  Regulates PtdIns(4,5)P2 homeostasis at the plasma membrane.  Heme-binding protein that may play a role in organic oxidant-induced stress responses.
What are the official names of this protein?
Phosphatidylinositol transfer protein SFH5, PITP SFH5.
What is the protein family that this protein belongs to?
Belongs to the SFH5 family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: IRAP_SALAR
Sequence: MKNLIAELLLKLAQKEEESKELVAQVEALEIIVTAMLRNMAQSEQQMLIRQVEGALEGVKPDASVPDHDTELLRQYVKKLLRHPRH
What is the function of this protein?
Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate and magnesium starvation, but also in stationary phase and during nitrogen starvation.  Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway.
What are the official names of this protein?
Anti-adapter protein IraP.
What is the protein family that this protein belongs to?
Belongs to the IraP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRXB_LISMO
Sequence: MASEEKIYDVIIIGAGPAGMTAALYTSRADLDTLMIERGVPGGQMVNTAEVENYPGFDSILGPDLSDKMLSGAKQFGAEYAYGDIKEVVDGKEFKTVTAGSKTYKARAIIIATGAEHRKLGAAGEEELSGRGVSYCAVCDGAFFKNRELIVVGGGDSAVEEGTYLTRYADKVTIVHRRDKLRAQQILQDRAFKDEKVDFIWNSTVEEIVGDGKKVTGAKLVSTVDGSESIMPVDGVFIYVGLVPLTKAFLNLGITDDEGYIVTDEEMRTNLPGIFAAGDVRAKSLRQIVTATGDGGLAGQNAQKYVEELKESLEAEAAK
What are the official names of this protein?
Thioredoxin reductase, TRXR.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_ECO8A
Sequence: MTATAQQLEYLKNSIKSIQDYPKPGILFRDVTSLLEDPKAYALSIDLLVERYKNAGITKVVGTEARGFLFGAPVALGLGVGFVPVRKPGKLPRETISETYDLEYGTDQLEIHVDAIKPGDKVLVVDDLLATGGTIEATVKLIRRLGGEVADAAFIINLFDLGGEQRLEKQGITSYSLVPFPGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBB6_GOSHI
Sequence: MREILHVQGGQCGNQIGSKFWEVICDEHGVDPTGKYNGDGSSDIQLERIDVYYNEASGGRYVPRAVLMDLEPGTMDSIRSGPIGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELIDAVLDVVRKEAENCDCLQGFQVCHSLGGGTGSGMGTLLISKIREEYPDRMMMTFSVFPSPKVSDTVVEPYNATLSVHQLVENADECMVLDNEALYDICFRTLKLTTPSFGDLNHLISATMSGVTCCLRFPGQLNSDLRKLAVNLIPFPRLHFFMVGFAPLTSRGSQQYVSLTVPELTQQMWDAKNMMCAADPRHGRYLTASAMFRGKMSTKEVDEQMMNVQNKNSSYFVEWIPNNVKSSVCDIPPRGLKTSSTFIGNSTSIQEMFRRVSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVAEYQQYQDATVEDEEEYEGEEGLDENYET
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta-6 chain, Beta-6-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: TILS_UREPA
Sequence: MKILIKLWTNLINRISNKKYLAAVSGGPDSMAMLNMYKRNIRVVCHVNYHKRESSDRDQQIVVDFCRKNNLIIEILDVDEKVYERYGHIDNFQTKARLIRYDFFKEIGKKYNIENLYIAHNFDDFLETAYMQRARQSKALFYGIKESNVINGIIVKRPVLFVRKQTLQRYCDENKIKYGIDETNELDIYERNRVRKIISSWSLNEVYDFKKFVIKYNKEHSSFANFIDLSYIEFKKNKYKYDYFIRQDDMVQYYLIYYFLIDHKIINPSENKIISLIKFFGKQINKEKAYRVQENIYMHVNDDELISLISYNKSDNISNSNVDIIDDHNVIEK
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_YARLI
Sequence: MALRKKNSLLNMANSYVLDSPQPSNLNYFWNFGSLLALCLVIQLATGITLAMHYTSHASLAFDSVEHIMRDVNFGWFIRYAHANTASFFFICIYAHMGRNIYYGSYKTPRVLPWSIGVIIFLLLIITAFMGYVLVFGQMSLWGATVICNLVSAIPWLGEDIVHFLWGGFSVGNPTLQRFFALHYLMPFVLAVFALLHLIALHTAGSSNPLGITSNVDKLSMHPYYSFKDLITVFAFLLMFTLFVFFSPDKLGHPDNYIPANPMVTPASIVPEWYLLPFYAILRAIPDKLGGVIAMVAAILILLILPIVDRSIIRGNAFKPISKLLFGFFICNFLLLGVLGQVHIEPPFIVLGQICTIFYFSYFLILLPMVSTIENIFFYIGSLRK
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: METK_CLOTE
Sequence: MRKLFTSESVTEGHPDKICDQISDAVLDAILERDPNGRVACETSVTTGMVLVTGEITTNCYVDIPKIVRNTIEAIGYTRAKYGFDSDTCAVLTSISEQSPDIAMGVDESLESKQGGMDKEDVIGAGDQGMMFGYANNETSEYMPMAISIAHKLSRRLSEVRKNGTLPYLRPDGKTQVTVEYEDNKAIRIDTIVVSTQHGPEVTREQIEKDIFEHVISKVVPVEFLDENTNYYINPTGRFVVGGPQGDAGLTGRKIIVDTYGGYGRHGGGAFSGKDPTKVDRSAAYAARWVAKNLVAAGVADKLEVQLAYAIGIAKPVSISVETFGTGKIDDRKIVEIINKVFDLRPSAIIKELNLRRPIYKQTAAYGHFGRTDVELPWESLNKLEEIKNLI
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: V248_FOWPN
Sequence: MEIKVESINNNFCKLSYEDIEIIMMKENEYINATRLCSSRGRDILDWMSKESSVELINELDRINRSCNDYYDYRGIVLNVVSDSETSELYVHRDLILHISHWISPLFSLKVVKFINSYIQDSYQLEYELIHKKSLMDQLKEIILLNDDNNM
What are the official names of this protein?
Uncharacterized protein FPV248, BamHI-ORF6.
Protein: MSBA_THIDA
Sequence: MSAPTSRHLYGRLLGYVKPHWRMFALSIVGLILTAATEPMLPALFKPLLDEGFVAKDQDFIRWVPLLLLGLFVLRGVASFISTYSMAWVGSRLVMDLRAAMFDKLMALPTRYFDQNPSGQLIAQLAFNVTQVTQSATSSLTTLVRDTVTVLGLLGYLVWLNWRLTLIVFALVPLTLWVVRVASKRLRGLSRKAQENIGDLTQVVDEAVGGHRVVKLYGGETYEQARFHRAANLARQFEMKRVAANAVYEPVIQFIAAIALAIIVFIAAGQASANTTTVGGFVAFFMAMLLLFAPLKRLTAVNDQLQRGLAASETIFALLDQDAERDTGTREPAHIEGRLAFRDVGLTYPGKQTPALARISLDIAPGETVALVGASGSGKTTLANLVPRFYDPDAGRIELDGVDIRDVKLQSLRGHIALVSQDVVLFNDTLAHNIAYGSKREASPDEIRAACVAAHAWDFIQAMPDGLDTLIGENGMRLSGGQRQRIAIARAILKNAPILILDEATSALDSESERHVQAALETLMQNRTTLVIAHRLSTIERANRIVVLEGGRIVETGAHADLLAKQGRYAQLHALQFSQ
What is the function of this protein?
Involved in lipopolysaccharide (LPS) biosynthesis.  Translocates lipid A-core from the inner to the outer leaflet of the inner membrane.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
What are the official names of this protein?
ATP-dependent lipid A-core flippase, Lipid A export ATP-binding/permease protein MsbA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: WEE2C_XENLA
Sequence: MRTAMSCGGGLVQRLDFSSSEEEDGLSNGINEAPQKGSPVSSWRTNNCPFPITPQRNERGLSPTQELSPSSDYSPDPSDKGAGGECPGTPLHYSTWKKLKLCDTPYTPKSLLYKTLPSPGSRVHCRGQRLLRFVAGTGAETEDPTLVNVNPFTPQSYRQTHFQPNGKRKERPEDDCSSDSQMKFTDKEHPSVFQSKRFVLRETNMESRYKTEFLEIEKIGAGEFGSVFKCVKRLDGCFYVIKRSKKPLAGSTDEQLALREVYAHAVLGHHPHVVRYYSAWAEDDHMIIQNEYCNGGSLQDLIMENNKKGQFVPEQELKEILLQVSMGLKYIHGSGLVHMDIKPSNIFICRKQTEVGEDESDGEDDVSSASVLYKIGDLGHVTSILNPQVEEGDSRFLANEILQEDYRQLPKADIFALGLTIALAAGAAPLPCNEDGWHHIRKGNLPHIPQPLTPAFLALLKLLVHPDPATRPPAASLAKNSVLRRCVGKAAELQKQLNVEKFKTAMLERELQAAKLAQDECLDLPPVSGFSCRGRKRLVGAKNARSLSFTCGGY
What is the function of this protein?
Protein tyrosine kinase that phosphorylates and inhibits cdk1 and acts as a regulator of meiosis in oocytes.  Required to ensure the meiotic cell cycle in oocytes by phosphorylating cdk1 at 'Tyr-15', leading to inhibit cdk1 activity and prevent meiosis (By similarity).
What are the official names of this protein?
Wee1-like protein kinase 2-C.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: OPSD_GALML
Sequence: MNGTEGENFYVPMSNKTGVVRNPFEYPQYYLADHWMFAVLAAYMFFLIITGFPVNFLTLFVTIQNKKLRQPLNYILLNLAVANLFMVFGGFTTTLITSMNGYFVFGSTGCNLEGFFATLGGEISLWSLVVLAIERYVVVCKPMSNFRFGSQHAIAGVSLTWVMAMACAAPPLVGWSRYIPEGLQCSCGIDYYTPKPEINNVSFVIYMFVVHFSIPLTIIFFCYGRLVCTVKAAAAQQQESETTQRAEREVTRMVVIMVIGFLICWLPYASVALYIFNNQGSEFGPVFMTIPSFFAKSSALYNPLIYILMNKQFRNCMITTLCCGKNPFEEEESTSASASKTEASSVSSSQVSPA
What is the function of this protein?
Photoreceptor required for image-forming vision at low light intensity.  While most salt water fish species use retinal as chromophore, most freshwater fish use 3-dehydroretinal, or a mixture of retinal and 3-dehydroretinal (By similarity).  Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins.  Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity).
What are the official names of this protein?
Rhodopsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell projection, cilium, photoreceptor outer segment. Note=Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to disk membranes in the rod outer segment (OS) photosensory cilia.