PharMolix/UniProtQA huggingface dataset:
Protein: DML1_YARLI
Sequence: MREIITLSFGQTAGHINADYFNSQEHYFPLATKSTSDPTVRFRRGVATDSRTETYNPRLLTWELKGGYGAFQAFNQFYTEGDKSQPQVWNEGEIKEIKEQPVDKNEYQKALDLGRENASQLNTDTTKRWTDYNRLFHHPKTRHQLDNWLFDPDTAPQGIHRGGDQKWTGFDVGVNEWEHVLNSDKEYLDSTLRSWVEECDSLGGLNVVVDDSAWAGVAAKILANYRDDFDAKGTVVTWSVEAKPEKKTRETQKNAIQTTVALSQVSSIYIPVSFPTKTPIDADFDPTSPWHQAALFGLSVYEPVQLMATQRTGGLSLDAMAALLDTTGERNIVSEVGGTLTDVDGDKSTVQYDSRLFQELFLPSRIPPKTPHVFSDLSIARLEDQDDDANSYRLNQPMPEVSSQPEFTKQFVSSKTRLAVTTKPRRTLLDMAKFVSVYERGDEREEMKQELGDMASKYEHGWEEESDDDDDY
What is the function of this protein?
Involved in the partitioning of the mitochondrial organelle and mitochondrial DNA (mtDNA) inheritance.
What are the official names of this protein?
Protein DML1.
What is the protein family that this protein belongs to?
Belongs to the misato family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PER_GINBI
Sequence: LSPTFYATSXPNVXXTRDSVVEIGQLADTVAPVRGFDVIDNIKDMVALSGSHTIGQARQATRSPAQVDLSNTRGLLGQAGNDFALVDDK
What is the function of this protein?
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.  These functions might be dependent on each isozyme/isoform in each plant tissue.  Active against p-coumaryl alcohol, coniferyl alcohol and coniferyl aldehyde.
What are the official names of this protein?
Peroxidase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: 3604L_ASFM2
Sequence: MNSLQVLTKKVLIETKAFSNYHEDDIFILQQLGLWWENGPIGFCKQCKMVTSGSMSCSDVDSYELDRALVKAVKENQTDLIKLFVLWGADINFGIICAKTKQTKDLCIQLGADPEFLDVGLYNMFVYLVKRKKVLLAIEIYYDNISILDSFDSHDFHVLIDFVYNRFILYLDEKEKEMTRNTLVLRFWYKFAIDFKLTKPIRYLSKKFPHLDLWRLQTAIYLGNIDEVHHAYFQENIRLRLNVMMFLACARPGNKLGIYYCFALGADLDHALERLISFNSINREINRKISGKTRLCIEGSYLSNIYFCIGLGANPYTKKIQETIKQKNSNIMILLYSKKKILSPHSVLQNKILDPSDVYKMISTYKNTESFYPFSSLAVKLIQQAK
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 360-4L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 360 family.
Protein: MUD1_SCHPO
Sequence: MNNLTPENIRQTILATPFLLNRIRTEFPQLAAVLNDPNAFATTWQSINASQLLQIPSSTYSMGMPSFSEDDLFDVEVQRRIEEQIRQNAVTENMQSAIENHPEVFGQVYMLFVNVEINGHKVKAFVDSGAQATILSADCAEKCGLTRLLDTRFQGVAKGVGMAKILGCVHSAPLKIGDLYLPCRFTVIEGRDVDMLLGLDMLRRYQACIDLENNVLRIHGKEIPFLGESEIPKLLANVEPSANAHGLGIEPASKASASSPNPQSGTRLGTKESVAPNNEGSSNPPSLVNPPTDPGLNSKIAQLVSMGFDPLEAAQALDAANGDLDVAASFLL
What is the function of this protein?
Recognizes and binds polyubiquitin chains (PubMed:11584278, PubMed:16138082).  Acts as a linker between the 19S proteasome and polyubiquitinated proteins via UBA domain interactions with ubiquitin for their subsequent degradation.  Aspartic protease.  Appears to act as negative regulator of constitutive exocytosis.  May act at the level of secretory vesicle docking and fusion as a competitive inhibitor of SNARE assembly.  Required for S-phase checkpoint control (By similarity).
What are the official names of this protein?
UBA domain-containing protein Mud1, DNA-damage-inducible protein DDI1 homolog, UBA domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the DDI1 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SPLA_STAAC
Sequence: MNKNVMVKGLTALTILTILTSLGFAENISNQPHSIAKAEKNVKEITDATKEPYNSVVAFVGGTGVVVGKNTIVTNKHIAKSNDIFKNRVSAHHSSKGKGGGNYDVKDIVEYPGKEDLAIVHVHETSTEGLNFNKNVSYTKFADGAKVKDRISVIGYPKGAQTKYKMFESTGTINHISGTFMEFDAYAQPGNSGSPVLNSKHELIGILYAGSGKDESEKNFGVYFTPQLKEFIQNNIEK
What are the official names of this protein?
Serine protease SplA.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1B family.
What are the subcellular locations of this protein?
Secreted.
Protein: F16PA_SALPK
Sequence: MKTLGEFIVEKQHEFSQATGELTALLSAIKLGAKIIHRDINKAGLVDILGASGAENVQGEVQQKLDLFANEKLKAALKARDIVAGIASEEEDEIVVFEGCEHAKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRVTPVGTPVTEEDFLQPGNKQVAAGYVVYGSSTMLVYTTGCGVHAFTYDPSLGVFCLCQERMRFPEKGKTYSINEGNYIKFPNGVKKYIKFCQEEDSSTSRPYTSRYIGSLVADFHRNLLKGGIYLYPSTASHPQGKLRLLYECNPMAFLAEQAGGKASDGKERILDIIPESLHQRRSFFVGNRHMVDDVERFIREYPDA
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENTH_ECO5E
Sequence: MIWKRHLTLDELNATSDNTMVAHLGIVYTRLGDDVLEAEMPVDIRTHQPFGLLHGGASAALAETLGSMAGFMMTRDGQCVVGTELNATHHRPVSEGKVRGVCQPLHLGRQNQSWEIVVFDEQGRRCCTCRLGTAVLG
What is the function of this protein?
Required for optimal enterobactin synthesis.  Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules.
What are the official names of this protein?
Proofreading thioesterase EntH, Enterobactin synthase component H.
What is the protein family that this protein belongs to?
Belongs to the thioesterase PaaI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DER_CHRSD
Sequence: MNPVIALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGNGVLGDKTYTVIDTGGISGNEEGLDAAMAEQSLLAIDEADIVLFMVDGRTGLNVADEAIANHLRVNQKKTWLVVNKTDGLEEHSAMAEFWRLGLGDPRPIAAAHGRNVTSLIDEVLAPFPPREANAAPPDLSNGIRIGVIGRPNVGKSTLVNRLLGEDRVVVYDEAGTTRDAIEIPFERRGKPYVLVDTAGVRRRKNVSEAAEKFSIIKTLEAIKACNVAIMVLDARSGLVEQDLHLLDYVLSSGRALVLAVNKWDGLEQEAKDKMRAAIKRRLGFADYAEMHFISALHGTAVGDLYPSITRAFDSANSHWSTNRLTTILQDAVSEHQPPLIHGRRIKLRMAHQGGSNPPIIVVHGNQTGSLPEAYKRYLTNTFRKVLKVRGTPLRFEFRSGKNPYDSNPDASDREKAKQRELGRTREARKNRR
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: LAMB1_KLEP7
Sequence: MNTTLRALSVALAAALIAPSAFAATAAIPTIDFHGYMRAGVGVSGDGSEAEWQKNKLGRLGNESDTYGELELGSEVYKKDDVSFYLDSMVSMVSDGSNDNETTLNDDAQFGLRQLNLQIKGLIPGDPNAVIWGGKRYYQRHDLHIIDTKYWNISGSGAGVENYTLGPGAVSLAWIRGDANDVDYRVDGDSNVNINYIDLRYAGWKPWAGSWTEFGIDYAMPNTTKKQDSYGGLYDADNGVMLTGEISQDMLGGYNKTVLQYANKGLAQNMVSQGGGWYDMWNYVNDATGYRVINTGLIPITEKFSINHVLTWGSADDITDYTDKTRMLSLVARGQYQFTDYVRLIGEVGGFYQKDSYNNGTSYKQAGEKYTIALGLADGPDFMSRPELRIFASYLNDSEDGKPFEDQTANNTWNFGVQVEAWW
What is the function of this protein?
Involved in the transport of maltose and maltodextrins.
What are the official names of this protein?
Maltoporin 1, Maltose-inducible porin 1.
What is the protein family that this protein belongs to?
Belongs to the porin LamB (TC 1.B.3) family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: LPPY_SHIFL
Sequence: MVQCVRHFVLPRLKKDAGLPFFFPLITHSQPLNRGAFFCLGVRR
What are the official names of this protein?
pyr operon leader peptide, pyrBI operon attenuator.
Protein: DAPA_POLAQ
Sequence: MTNKAHSQGSKKTIQGSMPAIVTPMFEDGSLDYPGLRALLDWHVSEGSDGIVIVGTSGESPTVSVEEHCELIRVTVEQIAGRIPVIAGTGGNSTQEAIELTHFAKKVGADASLQVVPYYNKPTQEGMYAHFKKIAESVDLPVILYNVPGRTVADMAGDTVVRLAGVPGIIGIKDATGSLERGTLLINDLKRAGHHEFSVFSGDDLTAAMLMLMGGHGNISVTANVAPRLMHELCVAAMSDDVKRTREIQYQLIAVHKAMFIEANPIPVKWALHEMGKITAGIRLPLTPLSSSLREPLKAALKQANLL
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_ANADE
Sequence: MKIQVETVSPVERKVTIEVDPDRVAKELDRAYASLSRRVKLRGFRPGKAPRKVLERQFKAEVEGEVAERIVTETFTEAVRVESLPVVAPPSVSITDGVAEGKPMRYSARVEVKPKLEPKDYKGLEVTRKPPEVTDESVSAELTKIQDSMAQLVAVEGRFEAQEGDWAVIDHEGTIDGKPFDGSTAEGVTVKVAPGPITEGNVEALKGKKIGDTVELDEPFPADHRDEALRGKTAHMKVTLKALKVRQAPALDDALAKELGIEGVETLDALRTRIRSDLEKREKRRAESELKDALVKAALAKNEFEVPPALVERAIDTMIEGAAERFARQGIDLRQLQLDVSRMRADLREQALLQVRGALLLEAIADAEKVEVTEEDLEAEAARIADELGMPLAKVQQQTRGKDAREALKNRIREEKALSLLSSAATIQQ
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: LEXA_ENT38
Sequence: MKALTARQQEVFDLIRDHISQTGMPPTRAEIAQRLGFRSPNAAEEHLKALARKGVLEIVSGASRGIRLLVEEETGIPLIGRVAAGEPLLAQQHIEGHYQVDPGMFKPSADFLLRVSGMSMKDIGILDGDLLAVHKTQDVRNGQVVVARIDDEVTVKRLKKQGNTVQLLPENSEFSPIVVDLREQTFSIEGLAVGVIRNGEWL
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: COFC_METFA
Sequence: MKVIIPVSPINSLKTRLSEFLSSEERKNLLLNMLRDIKKALEGLDVVVVSRDDEILDFAKYELKAEIVKEKYKGLNNAIKQAFDEIDDEEVIIIPADIPLIKKKHIEDILKLSKDYDLIIASSRGGGTNLLYLKSKNLIELRYEGFSFLKHLEEAEKRNLRYYIYDSFLISVDINTPEDLGEIFIHGDNTYTKNYLKGLGIEVEPKHSSAGRFVVKRR
What is the function of this protein?
Guanylyltransferase that catalyzes the activation of (2S)-2-phospholactate (2-PL) as (2S)-lactyl-2-diphospho-5'-guanosine, via the condensation of 2-PL with GTP.  It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
What are the official names of this protein?
2-phospho-L-lactate guanylyltransferase, LP guanylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CofC family.
Protein: RRS1_CAEEL
Sequence: MADKSTEVEKAIDPIIDLGNLLFIDREPIQGDASEGLEERARKNTQLLFNNIWQLEQKRVEEAIIVTLPPATYRLPREKRLPEKKEPTKWEKYAAEKGIEKRKKDKKVFDEATKEWKPTYGYRRGNDDTKDWLIEIPDNAEDPNKDFFAERREKKKERVAKNDMQRMKNLARQMKTTVKSGPSTEKMIGVGVDAKEKSKQQVRFAVDRAKLATASAGKFQEGLKGEKANVKTGKKRKFEANEAPVSGEKERALQILQRMKSKKAKIVEEKAAAVAGPLREKKEKSERKGAKDQTRQKSQIHRQQWFKNKVDGKKKGTGGAGKKGANKAKARKG
What is the function of this protein?
Involved in ribosomal large subunit assembly.
What are the official names of this protein?
Ribosome biogenesis regulatory protein homolog.
What is the protein family that this protein belongs to?
Belongs to the RRS1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PURA_TALMQ
Sequence: MVTIVLGSQWGDEGKGKITDYLSQDATLCCRAAGGHNAGHTIVHDSVTYDFHILPSGLVSPKCINLIGAGTVVHIPSFFKELGALAEKGLVDADKRIFISDRAHVCFDLHSVVDGLEEAKLGGRKVGTTGKGIGPCYSDKAARRGVRVGEILDEEVFERKLRNLHSGYRNRFGELAYDVEEEINRFKEYRQKLKPYIIDQLPFLQKYKNDDRILVEGANALLLDLDHGTYPYVTSSSTGLGGAIQGLSINPTKIKNIIGVVKAYTTRVGSGPFPTEQLNEFGEKLQVTGREFGVTTGRKRRCGWFDLVLCRYSLAVNHYTALNLTKLDILDDFDEIKVAVAYKLPDGTRLESSYPADAGVIEKLEVEYVTLPGWKSNTMGLTKYEDLPENARKYVEYIEKGLDGVPIKWIGTGPAREHLIIR
What is the function of this protein?
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSGA_STACT
Sequence: MRTGRIIKSLSGVYRVDSDGEMFDTKPRGLFRKKKFSPIVGDIVDFEIENVTEGYIQHVHERQNELKRPPVSNIDHLVIVMSAVEPDFSTQLVDRFLVIAHSYGLNPRIVVTKKDMASDSQIERIEKDLDVYRAIGYPVQFVGKNDNIETIFDEWGSGLAVLSGQSGVGKSTLLNAYRPDLAIETNQISKSLNRGKHTTRHVELFERKGGFVADTPGFSALDFDHIHKDEVKDYFLEIQEYGQGCKFRNCNHIKEPQCNVKAQVEAGNIAQFRYDHYVQLFEEIANRKERY
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIDA_PONAB
Sequence: MSEVTRSLLQRWGASFRRGADFDSWGQLVEAIDEYQILARHLQKEAQAQHNNSEFTEEQKKTIGKIATCLELRSAALQSTQSQEEFKLEDLKKLEPILKNILTYNKEFPFDVQPVPLRRILAPGEEENLEFEEDEEEGGAGAGSPDSFPARVPGTLLPRLPSEPGMTLLTIRIEKIGLKDAGQCIDPYITVSVKDLNGIDLTPVQDTPVASRKEDTYVHFNVDIELQKHVEKLTKGAAIFFEFKHYKPKKRFTSTKCFAFMEMDEIKPGPIVIELYKKPTDFKRKKLQLLTKKPLYLHLHQTLHKE
What is the function of this protein?
Acts as a ventralizing factor during embryogenesis.  Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization.  This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling (By similarity).
What are the official names of this protein?
Axin interactor, dorsalization-associated protein, Axin interaction partner and dorsalization antagonist.
What is the protein family that this protein belongs to?
Belongs to the AIDA family.
Protein: RL15_GLOC7
Sequence: MNLHELAPQKGATKRRRRVGRGISAGQGASCGFGMRGQKSRSGTGTKPGFEGGQMPLYRRIPKLKHFPLVNRRQYTIINVGQLASLDPNSEVTLETLMDAGLITTNDGPLKILGNGELTIPLTIKAAAFTKGAQEKIEAAGGSCVVESSGSQKQ
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: CS13A_HERHM
Sequence: MKLTRRRISGNSVDQKITAAFYRDMSQGLLYYDSEDNDCTDKVIESMDFERSWRGRILKNGEDDKNPFYMFVKGLVGSNDKIVCEPIDVDSDPDNLDILINKNLTGFGRNLKAPDSNDTLENLIRKIQAGIPEEEVLPELKKIKEMIQKDIVNRKEQLLKSIKNNRIPFSLEGSKLVPSTKKMKWLFKLIDVPNKTFNEKMLEKYWEIYDYDKLKANITNRLDKTDKKARSISRAVSEELREYHKNLRTNYNRFVSGDRPAAGLDNGGSAKYNPDKEEFLLFLKEVEQYFKKYFPVKSKHSNKSKDKSLVDKYKNYCSYKVVKKEVNRSIINQLVAGLIQQGKLLYYFYYNDTWQEDFLNSYGLSYIQVEEAFKKSVMTSLSWGINRLTSFFIDDSNTVKFDDITTKKAKEAIESNYFNKLRTCSRMQDHFKEKLAFFYPVYVKDKKDRPDDDIENLIVLVKNAIESVSYLRNRTFHFKESSLLELLKELDDKNSGQNKIDYSVAAEFIKRDIENLYDVFREQIRSLGIAEYYKADMISDCFKTCGLEFALYSPKNSLMPAFKNVYKRGANLNKAYIRDKGPKETGDQGQNSYKALEEYRELTWYIEVKNNDQSYNAYKNLLQLIYYHAFLPEVRENEALITDFINRTKEWNRKETEERLNTKNNKKHKNFDENDDITVNTYRYESIPDYQGESLDDYLKVLQRKQMARAKEVNEKEEGNNNYIQFIRDVVVWAFGAYLENKLKNYKNELQPPLSKENIGLNDTLKELFPEEKVKSPFNIKCRFSISTFIDNKGKSTDNTSAEAVKTDGKEDEKDKKNIKRKDLLCFYLFLRLLDENEICKLQHQFIKYRCSLKERRFPGNRTKLEKETELLAELEELMELVRFTMPSIPEISAKAESGYDTMIKKYFKDFIEKKVFKNPKTSNLYYHSDSKTPVTRKYMALLMRSAPLHLYKDIFKGYYLITKKECLEYIKLSNIIKDYQNSLNELHEQLERIKLKSEKQNGKDSLYLDKKDFYKVKEYVENLEQVARYKHLQHKINFESLYRIFRIHVDIAARMVGYTQDWERDMHFLFKALVYNGVLEERRFEAIFNNNDDNNDGRIVKKIQNNLNNKNRELVSMLCWNKKLNKNEFGAIIWKRNPIAHLNHFTQTEQNSKSSLESLINSLRILLAYDRKRQNAVTKTINDLLLNDYHIRIKWEGRVDEGQIYFNIKEKEDIENEPIIHLKHLHKKDCYIYKNSYMFDKQKEWICNGIKEEVYDKSILKCIGNLFKFDYEDKNKSSANPKHT
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  Unlike many single-component effectors, this CRISPR-Cas system targets RNA (PubMed:28475872).  CRISPR clusters are usually transcribed from pre-CRISPR RNA (crRNA) and processed into crRNA but this protein does not have detectable pre-cRNA processing activity on any tested pre-crRNA (PubMed:28475872).  Cleaves linear target ssRNA in a pre-crRNA-dependent fashion, preferentially before U residues (PubMed:28475872).  Binding a viable target RNA target activates this protein for non-specific RNA degradation in vitro (called collateral RNA degradation), but it is not very sensitive as it requires nanomolar levels of viable target RNA (PubMed:28475872).
What are the official names of this protein?
CRISPR-associated endoribonuclease Cas13a, EndoRNase, HheCas13a.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endoribonuclease Cas13a family.
Protein: G6PI1_CLAWI
Sequence: MASPALISETEAWKDLKAHLEGIKMTHLRELMGDTERCQSMMLEFDNIFLDYSRQQASPDTISKLYRLADAAHLKQKIDHMYNGDHINSTENRSVLHVALRAPRNLAICSDGKNVVPDVWNVLDKIKDFSDRVRNGSWIGATGKELKDVIAVGIGGSFLGPLFVHTALQTDPEASKNARGRELRFLANVDPIDVARNISGLSPETTLVVVVSKTFTTAETMLNARTLREWISSALGPSAVAKHMVAVSTNIPLVEKFGIDPNNAFAFWDWVGGRYSVCSAVGVLPLSLQYGFAVVEKFLQGAHSIDQHFSSAPFEKNIPVLLGLLSVWNVSFLGYPARAILPYSQALEKLAPHIQQVSMESNGKGVSIDGLPLPFESGEIDFGEPGTNGQHSFYQLIHQGRVIPCDFIGVVKSQQPVYLKGEVVNNHDELMSNFFAQPDALAYGKTPEQLKKENVSEHLIPHKTFTGNRPSISLLLPTLDAYRIGQLLAIYEHRVAVQGFVWGINSFDQWGVELGKSLATQVRKQLHGSRVKGEPVEGFNFSTKTLLTRYLEATSDVPADPSTLLPNI
What are the official names of this protein?
Glucose-6-phosphate isomerase, cytosolic 1, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IDI2_BACC4
Sequence: MVRAKRKLDHIEYALSTGQSRTHGFHDIDFVHQSLPNSNYDTITCETKIGELSLSSPIFINAMTGGGGEKTLHINEQLAYVAKHHNLAMAVGSQMAALKDESEAASYKVIRKVNPNGIFFANLGSEATIEQAERAVDMIEANALQIHLNVIQELTMPEGDRDFTGVLQRIEKIVLNSKVPIIVKEVGFGMSKETMQQLVNVGVTAIDIGGQGGTNFAAVENERRQRMLSYFNNWGIQTATSIIEATSTNNNLSFIASGGIQTALDVAKAIALGANTTAFAGYFLRILMQDGIEKLLDEIELLHTDLKFIMTALGAKTIEELQSVPLVVKGETYHWLMQRGIDTAHYSRR
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YABQ_BACSU
Sequence: MTLTTQFYTMLAMSGMGLWLGASLDTYRLFVIRAKTARWLLFIHDILFWIMQGLLFFYVLLHVNEGEFRIYIFLAVLLGVATYQSLCKRIYIKILKFVIYLVVSVYQFFKKLIQHVLFRPIVWTCGAIIWLAAFLFKKTYSLIGFLLLCLYKIVMVLCFPIRFIAKQCLKLLPVKMRLTFRRYFEKGAGFLKKKKKLLITIRTTITRFLKR
What is the function of this protein?
Required for sporulation.  Plays an important role in cortex and coat formation.
What are the official names of this protein?
Spore protein YabQ.
What are the subcellular locations of this protein?
Forespore outer membrane; Multi-pass membrane protein.
Protein: TYSY_PSEAE
Sequence: MKQYLDLMRHVREHGTFKSDRTGTGTYSVFGHQMRFDLAAGFPLVTTKKCHLKSIVHELLWFLKGSTNIAYLKEHGVSIWDEWADENGDLGPVYGYQWRSWPAPDGRHIDQIANLMAMLKKNPDSRRLIVSAWNPALIDEMALPPCHALFQFYVADGKLSCQLYQRSADIFLGVPFNIASYALLTLMVAQVAGLQPGEFIWTGGDCHLYANHLEQADLQLTREPLPLPSMKLNPEVKDLFDFRFEDFELVGYEAHPHIKAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIE_SALAR
Sequence: MYQPDFPPVPLRLGLYPVVDSVAWIECLLAAGVRTIQLRIKDKRDAEVEADVVAAITLGRRYDARLFVNDYWRLAIKHQAYGVHLGQEDLKTTDLNAIRTAGLRLGVSTHDDMEIDIALAARPSYIALGHVFPTQTKQMPSAPQGLEQLARHIERLADYPTVAIGGISLKRAPAVLATGVGSIAVVSAITQAADWRAATAQLLAIAGVGDE
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: SYR_NOSS1
Sequence: MNATQEQLKIKLEQALVAAFGDEYAGVDPILVSASNPKFGDYQANVALSLSKKLGQQPRAIASAIVEKLDVSEICEKPEIAGPGFINLKLKTAYLEAQLNTIQADTRLGVPTAKHPQREIVDFSSPNIAKEMHVGHLRSTIIGDSIARILEFRGHDVLRLNHVGDWGTQFGMLITYLREVSPEALTTANALDIGDLVSFYRQAKQRFDADEAFQETARQEVVRLQAGAADTLHAWKLLCEQSRQEFQVIYDLLDVKLTERGESFYNPLLPTVVENLEKSGLLVENQGAKCVFLDGFTNREGEPLPLIVQKSDGGYNYATTDLAALRYRIQKDEAKRIIYITDAGQANHFAQFFQVARKAGWIPDDVELVHVPFGLVLGEDGKKFKTRSGDTVRLRDLLDEAISRAHADVEVRLKAEEREETAEFIDKVAEVVGISAVKYADLSQNRTSNYIFSYDKMLDLKGNTAPYMLYAYARIQGISRKGEINFADLGDNAKVILQHETEFALAKYLLQLGEVISTVEEDLSPNRLCEYLYELSKRFNAFYDRNQGVQVLSAEEPLRTSRLVLCDLTARTLKLGLSLLGIQVLERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDC_MYCLE
Sequence: MTAPKIEAVYTVGAYLLDRLAELGVTEIFGVPGDYTLEFLDHIVAHPTIRWVGNANELNAGYAADGYGRLRGISALVTTFGVGELSAANAIAGSYAEHVPVVHIVGAPPKDAQSTHRALHHSLGDGDFEHFIRISSEITCSQANLTTATACKEIDRVLSEVRKHKRPGYILLSTDVARFPTEPPAAPLPGHTDGTSPRALSLFIDAATKLIADKRMTVLADLLVHRLQVVKELETLLTADVVPYATLMWGKSLLDESSPNFLGIYAGAASTEAVRAAIEQAPVLVTAGVVFTDMVSGFFSQRIDPARTIDVGQYQSSVADKVFTPLEMGDALEALASILVRRGVSSPPVELPPGNPTADTPSPTQRLTQQILWDRLCAALTPGNVVLADQGTAFYGMVEHRLPRGVTFIGQPLWGSIGYTLPAALGAGLAHRNRRTVLLLGDGAAQLTIQELGSFYREGLSPVIVVVNNDGYTIERAIHGATAPYNNIARWRWTDIPGALGVANHSSFRAETYGELDEAFAVAAELKDQMVFVEVIVPKLDLPSLLTALTRPAQDSNRIFQLPNPGWDN
What is the function of this protein?
Decarboxylates branched-chain and aromatic alpha-keto acids to aldehydes.
What are the official names of this protein?
Alpha-keto-acid decarboxylase, KDC.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.