PharMolix/UniProtQA huggingface dataset:
Protein: CH60_EHRRW
Sequence: MANMVVTGEQLDKSIREVVRILEDAVGCTAGPKGLTVAISKPYGAPEVTKDGYKVMKSIKPEDPLALAIANIIAQSASQCNDKVGDGTTTCSILTAKVIEEVSKVKAAGADIICVREGVLKAKEAVLEALKCMKREVLSEEEIAQVATISANGDKNIGTKIAQCVKEVGKDGVITVEESKGFKELDVEKTDGMQFDRGYLSPYFVTNSEKMLVEFENPYILLTEKKLNIIQPLLPILENIARSGRPLLIIAEDVEGEALSTLVLNKLRGGLHVAAVKAPGFGDRRKDMLGDIAILTGAKHVINDELAIKMEDLTLCDLGTAKNIRITKDTTTIIGSVDNSCAHVQSRICQIRMQIDNSTSDYDKEKLQERLAKLSGGVAVLKVGGSSEVEVKERKDRVEDALHATRAAVEEGVVPGGGAALLYTLSALDNLKSKNDDEQLGINIVKRALQAPIKRIIKNAGSENAPCVIAHLLKQNDKELIFNVDVMNFANAFTSGVIDPLKVVRIAFDFAVSLAAVFMTLNAIVVDIPSKDDNSAAGGAGMGGMGGMGGF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2AZ_DEBHA
Sequence: MSGKGKVHGGKGKSSETAKSTTSHSARAGLQFPVGRIKRYLKRTAQNKIRVGSKSAIYLTAVLEYLTAEVLELAGNAAKDLKVKRITPRHLQLAIRGDEELDNLIKATIAFGGVLPHINKALLLKVEKKKQK
What is the function of this protein?
Variant histone H2A which can replace H2A in some nucleosomes.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.  This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activation signal is received.  Near telomeres, it may counteract gene silencing caused by the spread of heterochromatin proteins.  Required for the RNA polymerase II and SPT15/TBP recruitment to the target genes.  Involved in chromosome stability (By similarity).
What are the official names of this protein?
Histone H2A.Z.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: ERF62_ARATH
Sequence: MITPIHTQHSLILVYINIYSPPILSKLRTGFILWTNTQKTNKKRNMEDQFPKIETSFMHDKLLSSGIYGFLSSSTPPQLLGVPIFLEGMKSPLLPASSTPSYFVSPHDHELTSSIHPSPVASVPWNFLESFPQSQHPDHHPSKPPNLTLFLKEPKLLELSQSESNMSPYHKYIPNSFYQSDQNRNEWVEINKTLTNYPSKGFGNYWLSTTKTQPMKSKTRKVVQTTTPTKLYRGVRQRHWGKWVAEIRLPRNRTRVWLGTFETAEQAAMAYDTAAYILRGEFAHLNFPDLKHQLKSGSLRCMIASLLESKIQQISSSQVSNSPSPPPPKVGTPEQKNHHMKMESGEDVMMKKQKSHKEVMEGDGVQLSRMPSLDMDLIWDALSFPHSS
What is the function of this protein?
Probably acts as a transcriptional activator.  Binds to the GCC-box pathogenesis-related promoter element.  May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
What are the official names of this protein?
Ethylene-responsive transcription factor ERF062.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: URED_BURM9
Sequence: MSAHEPHTSLVRPAAKAWHARLELGFERQPGGRTALAHRRHVGPLRVQRALYPEGDAICHAVIVHPPGGVAGGDRLEIDVRLDAGTHAVLTTPGATKWYKSNGLDARQRIDIDVGAHAKLDWLPQNNLFFDAAHASLEFVLALGDGASVLGWDATQLGRQAAGEAWSAGSIASFSKIVGPSGRPLWVERARLDAGDPLRAAPQGLGGFAVYGTLWALGAACTEALAESIAPALPFDDALRAGVTCVAPGTLLIRALAHSMEALQRLLAEQWLALRPIVHGVDPKPLRLWQT
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RN2G_LITPA
Sequence: DDGVEMTEEEVKRGIMDTVKNAAKDLAGQLLDKLKCKITAC
What is the function of this protein?
Antimicrobial peptide.
What are the official names of this protein?
Ranatuerin-2PLg.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Ranatuerin subfamily.
Protein: GLGB_GRABC
Sequence: MNALDPDTLIHPDVATAIIHGRHGDPFSVLGIHTTREGVVLRSFQPEATSVVAINPESGQEIATLHRVHGDGIFAARLPGRTGYRLKIVTATGTDIIDDPYVFPNLLGDLDVYLLAEGRHEDLGRVLGAHVTTMHSPDGREVEGVRFAVWAPNATRASVIGSFNHWDGRCHPMRKRVEAGVWELFIPGLTAGTIYKYELLGPNGELLPLKADPVAWYAEIPPATASIVASPAPFQWTDEQWMQQRGRLQAADQPISIYEVHPTSWMPAKCGDWNTLADRLIPYVQSLGFTHVEFLPVMEHPFGGSWGYQPLGQFAPMARLGTPESFASLVNRLHEVGIGVILDWVPAHFPTDAHGLARFDGTALYEHEDPREGYHYDWNTYIYNLGRNEVRAFLISSAVHWLTYFHADALRVDAVASMLYRDYSRKHGEWIPNMYGGRENLESVSFLQHLSTVVKSRAPGAVLIAEESTAWPGVTRPAHEGGLGFDYKWNMGWMHDTLHYMQEDPVNRSWHHDQMTFGLVYAFSEKFVLPLSHDEVVHGKRSLLGRMPGDEWQRFANLRAYYGFMWTHPGKKLLFMGGEIAQEQEWSEGHGTDWYLLDRPNHQGVQRLVADLNMLYRAEPALYRKDCAWDGFSWLVIDDRTQSVFAYMRYGADSDAPVLVVCNLTPVPRHDYRIGVPQGGYWREILNTDAGIYGGSNTGNGGGRMADATPSHHHPASLQLTLPPLATIILKPES
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: UPP_STRE4
Sequence: MGKCQVISHPLIQHKLSILRRQDTSTKDFRELVNEIAMLMGYEVSRDLPLEDVEIQTPVAKTVQKQLAGKKLAIVPILRAGIGMVDGFLSLVPAAKVGHIGMYRNEETLEPVEYLVKLPEDIDQRQIFIVDPMLATGGSAILAVDSLKKRGAANIKFVCLVAAPEGVKKLQEAHPDVDIYTAALDERLNDHGYIVPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: TPS8_PHYDL
Sequence: MNSTSRRSANYKPTIWNNEYLQSLNSIYGEKRFLEQAEKLKDEVRMLLEKTSDPLDHIELVDVLQRLAISYHFTEYIDRNLKNIYDILIDGRRWNHADNLHATTLSFRLLRQHGYQVSPEVFRNFMDETGNFKKNLCDDIKGLLSLYEASYLLTEGETIMDSAQAFATHHLKQKLEENMNKNLGDEIAHALELPLHWRVPKLDVRWSIDAYERRQDMNPLLLELAKLDFNIAQSMYQDELKELSRWYSKTHLPEKLAFARDRLVESYLWGLGLASEPHHKYCRMMVAQSTTLISIIDDIYDVYGTLDELQLFTHAVDRWDIKYLEQLPEYMQICFLALFNTVNERSYDFLLDKGFNVIPHSSYRWAELCKTYLIEANWYHSGYKPSLNEYLNQGLISVAGPHALSHTYLCMTDSLKEKHILDLRTNPPVIKWVSILVRLADDLGTSTDELKRGDNPKSIQCHMHDTGCNEEETRAYIKNLIGSTWKKINKDVLMNFEYSMDFRTAAMNGARVSQFMYQYDDDGHGVPEGKSKERVCSLIVEPIPLP
What is the function of this protein?
Sesquiterpene synthase involved in the biosynthesis of (+)-epi-alpha-bisabolol, a precursor of the natural sweetner hernandulcin.
What are the official names of this protein?
(+)-epi-alpha-bisabolol synthase, Terpene synthase 8, LdTPS8.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: LEU1_AERHH
Sequence: MSDRVIIFDTTLRDGEQALAASLTVKEKLQIAQALERLGVDVMEVGFPVSSPGDFQSVQTIARHIKQSRVCALARALPKDIDAAGEALRVAEAFRIHTFISTSSIHVESKLKKSFEDVLEMGVSAIKHARRYTDDVEFSCEDAGRTPIDNLCRMVEAAIKAGARTINIPDTVGYTVPTEFSGIIQTLFNRVPNIDQAIISVHCHDDLGLSVANSIGAVQMGARQIECTINGIGERAGNCSLEEVAMILKTRADLLGVHTNIRHSEIHRTSALVSQLCNMPVQPNKAIVGANAFSHSSGIHQDGVLKAKNTYEIITPESIGLTQNNLNMTSRSGRHVIKHRMESMGYAESSYDLDDLYGKFLTLADKKGQVFDYDLEALAFFSQIHEEPEHFKLEYLGVQSGSSVMATASVKLKVGQEIVSEAATGNGPVDAVYQCINRITGYEISIDKYELKGKGEGKNALGQVDIVAQYKGRKFHGMGLATDIIESSAQALIHVINSIWRADQVAEQMERNVAKTDKINTESV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: ODP2_ECOLI
Sequence: MAIEIKVPDIGADEVEITEILVKVGDKVEAEQSLITVEGDKASMEVPSPQAGIVKEIKVSVGDKTQTGALIMIFDSADGAADAAPAQAEEKKEAAPAAAPAAAAAKDVNVPDIGSDEVEVTEILVKVGDKVEAEQSLITVEGDKASMEVPAPFAGTVKEIKVNVGDKVSTGSLIMVFEVAGEAGAAAPAAKQEAAPAAAPAPAAGVKEVNVPDIGGDEVEVTEVMVKVGDKVAAEQSLITVEGDKASMEVPAPFAGVVKELKVNVGDKVKTGSLIMIFEVEGAAPAAAPAKQEAAAPAPAAKAEAPAAAPAAKAEGKSEFAENDAYVHATPLIRRLAREFGVNLAKVKGTGRKGRILREDVQAYVKEAIKRAEAAPAATGGGIPGMLPWPKVDFSKFGEIEEVELGRIQKISGANLSRNWVMIPHVTHFDKTDITELEAFRKQQNEEAAKRKLDVKITPVVFIMKAVAAALEQMPRFNSSLSEDGQRLTLKKYINIGVAVDTPNGLVVPVFKDVNKKGIIELSRELMTISKKARDGKLTAGEMQGGCFTISSIGGLGTTHFAPIVNAPEVAILGVSKSAMEPVWNGKEFVPRLMLPISLSFDHRVIDGADGARFITIINNTLSDIRRLVM
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
What are the official names of this protein?
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex, E2.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoacid dehydrogenase family.
Protein: RL6_FRATH
Sequence: MSRIGKKPVVIPSGVTINVAAGNKVEVKGAKATLSKTFSTDVTFSVADNVATITPNNNSKNAVAQSGTARAILSNMVEGVSKGFERKLKIIGVGYRAKAQGNELNLTLGFSHPVVYKLPQGITAETPAPTEIILKGADKELLGKVASEVREYRKPEPYKGKGVRYEDEYVAKKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: NEDD1_MOUSE
Sequence: MQENLRFASSGDDVKIWDASFLTLVDKFNPHTSPHGISSICWSSNNNFLVTASSSGDKIVVSSCKCKPVPLLELAEGQKQTCVDLNSTSMYLASGGLNNTVNIWDLKSKRLHRSLKDHKCEVTCVAYNWNDCYIASGSLSGEIILHSVTTNTSSTPFGHGSKQPIRHIKYSLFRKSLLGSVSDNGVVTLWDVNSQSSYHTFDSTHKAPASGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTPLTAVDFMPDGATLAIGSSRGKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYSTSLTKASLSKGSSNKATAVNKRSVPVSSSSGAAQNSGIVREAPSPSIATVLPQPVTTALGKGSGAAQDEAGLARSKSTDIFSKETDAGKSQDFSSFDDTGKNSLGDMFSPIRDDAVVSKGGDESIGKGDGLDFLPQLNSVFPLRKNAGASSSLVLHSSPLNVLMGSSGKEENESHEPSAESKRAYLGKQEPKDAMKQFTKLISSGAEPGILNTCPSSNQARNLEKFEKPEKDIEAQLIHEPSVNGSSTTVPKAASSVTAGVASSLSEKIVDTLGNSRPGAPLTSVQIRFIQNMIQETLDDFREACHRDIVNLQVEMIKQFHIQLNEMHSLLERYSVNEGLVAEIERLREENKRLRAHF
What is the function of this protein?
Required for mitosis progression.  Promotes the nucleation of microtubules from the spindle (By similarity).  May play an important role during the embryonic development and differentiation of the central nervous system (PubMed:1378265).
What are the official names of this protein?
Protein NEDD1, Neural precursor cell expressed developmentally down-regulated protein 1, NEDD-1.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: VPS53_HUMAN
Sequence: MMEEEELEFVEELEAVLQLTPEVQLAIEQVFPSQDPLDRADFNAVEYINTLFPTEQSLANIDEVVNKIRLKIRRLDDNIRTVVRGQTNVGQDGRQALEEAQKAIQQLFGKIKDIKDKAEKSEQMVKEITRDIKQLDHAKRHLTTSITTLNHLHMLAGGVDSLEAMTRRRQYGEVANLLQGVMNVLEHFHKYMGIPQIRQLSERVKAAQTELGQQILADFEEAFPSQGTKRPGGPSNVLRDACLVANILDPRIKQEIIKKFIKQHLSEYLVLFQENQDVAWLDKIDRRYAWIKRQLVDYEEKYGRMFPREWCMAERIAVEFCHVTRAELAKIMRTRAKEIEVKLLLFAIQRTTNFEGFLAKRFSGCTLTDGTLKKLESPPPSTNPFLEDEPTPEMEELATEKGDLDQPKKPKAPDNPFHGIVSKCFEPHLYVYIESQDKNLGELIDRFVADFKAQGPPKPNTDEGGAVLPSCADLFVYYKKCMVQCSQLSTGEPMIALTTIFQKYLREYAWKILSGNLPKTTTSSGGLTISSLLKEKEGSEVAKFTLEELCLICNILSTAEYCLATTQQLEEKLKEKVDVSLIERINLTGEMDTFSTVISSSIQLLVQDLDAACDPALTAMSKMQWQNVEHVGDQSPYVTSVILHIKQNVPIIRDNLASTRKYFTQFCVKFANSFIPKFITHLFKCKPISMVGAEQLLLDTHSLKMVLLDLPSISSQVVRKAPASYTKIVVKGMTRAEMILKVVMAPHEPLVVFVDNYIKLLTDCNTETFQKILDMKGLKRSEQSSMLELLRQRLPAPPSGAESSGSLSLTAPTPEQESSRIRKLEKLIKKRL
What is the function of this protein?
Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN).  The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD (PubMed:15878329, PubMed:18367545).  Acts as component of the EARP complex that is involved in endocytic recycling.  The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane (PubMed:25799061).
What are the official names of this protein?
Vacuolar protein sorting-associated protein 53 homolog.
What is the protein family that this protein belongs to?
Belongs to the VPS53 family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Recycling endosome. Note=Localizes to the trans-Golgi network as part of the GARP complex, while it localizes to recycling endosomes as part of the EARP complex (PubMed:25799061).
Protein: RSMH_NOVAD
Sequence: MSAETGSRAPHIPVLLEEVVAALDPKPGDLIVDATFGAGGYTRRLLDAGATVHAFDRDPDAIAAGKLWGETCGKEPRLVLHPRRFSEIAEGLAEAGIAGVQGVVFDIGVSSMQLDQAARGFAFSSDGPLDMRMSQEGPSAADFLNEADEGEIADVLYRYGEERQSRRIARAIVAARPLTTTAQFAAVVRKALGYRPDIKGPKAPKDPATRSFQAVRIHVNGELDELVQGLAAAEKVLVPGGRIAVVSFHSLEDRIVKQFLREGAGAVPAGSRHLPQLESKVQAVFEKPSGAIRPTPEEEARNPRARSATLRCAVRTAAPARAHQGRAAA
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPU_HV192
Sequence: MLELIGRIDYRLGVGALIVALIIVIIVWTIAYIEYRKLVRQRRIDWLVKRIKERAEDSGNESGGDTEELETMVDMGHLRLLDGNDL
What is the function of this protein?
Enhances virion budding, by targeting human CD4 and Tetherin/BST2 to proteasome degradation.  Degradation of CD4 prevents any unwanted premature interactions between viral Env and its host receptor CD4 in the endoplasmic reticulum.  Degradation of antiretroviral protein Tetherin/BST2 is important for virion budding, as BST2 tethers new viral particles to the host cell membrane.  Mechanistically, Vpu bridges either CD4 or BST2 to BTRC, a substrate recognition subunit of the Skp1/Cullin/F-box protein E3 ubiquitin ligase, induces their ubiquitination and subsequent proteasomal degradation.  The alteration of the E3 ligase specificity by Vpu seems to promote the degradation of host IKBKB, leading to NF-kappa-B down-regulation and subsequent apoptosis.  Ion channel activity has also been suggested, however, formation of cation-selective channel has been reconstituted ex-vivo in lipid bilayers.  It is thus unsure that this activity plays a role in vivo.
What are the official names of this protein?
Protein Vpu, U ORF protein, Viral protein U.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 VPU protein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass type I membrane protein.
Protein: LSM12_XENLA
Sequence: MAGPGEYFAIGAYVSCRTCQETRLQGEVVAFDYPSKMLALKCPSSSGKANHADILLLNLDYVSDVEVINERTQTPPPLASLNITKLASRARLEKEEKLSQAYAISAGVSLDGQQLFQTIHKTIKDCKWQEKNIVVMDEVVISPPYQVENCKGKEGRALTHVCKIVEKHFRDVENQKGVQRNPVAQSQKETSTSS
What is the function of this protein?
Nicotinic acid adenine dinucleotide phosphate (NAADP) binding protein.
What are the official names of this protein?
Protein LSM12.
What is the protein family that this protein belongs to?
Belongs to the LSM12 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_BRUSI
Sequence: MSDKTNDDKTLSVNPKKTLTLKRPGVEQSTVRQNFSHGRTKAVVVETKKRKFSRPDEKPEVEAAAAPKPAAPAAAPQQAPASAPVSASAAQASAPQPAPVKAPATKAPAAPSAPVTKPHVAQQRPVHQRPGGQQAQRPRPADRSGMVLNTLSRSEMDARRRALEEAQIREVEERARAVEEAKRRAEEDARRAKEREESARRQAEEEARLKAEAEARRKAEEEAAKRMPQPEARSERRDDARPAPYGARPQQAGRPQGGRPQPAGRPQQGSPRPAPIIADAAPIAGKPLPQSQLRKPGQSDDDDDRRSGAARRGVAAKPEVRAPKVVKGEDDRRRGKLTLTSNLEEEGRSRSLSAMRRRQEKFKRSQMQETREKISREVTIPETITLQELAQRMAERSVDIIKYLMKQGQMMKPGDVIDADTAQLIAEEFGHTVKRVAESDVEEGIFDVADNESAMVSRPPVVTIMGHVDHGKTSLLDAIRHANVVSGEAGGITQHIGAYQVVQNGQKITFIDTPGHAAFTAMRARGAQATDIAILVVAADDSVMPQTIESINHAKAAGVPIIVAINKIDKPAADPQKVRTALLQHEVFVESMGGEVLDVEVSAKNKINLDKLLDAVLLQAEMLDLKADPDRTAEGVVIEAQLDRGRGSVATVLIQKGTLHPGDILVAGSEWGRVRALVNDRGEHVKEAGPAMPVEILGLQGTPQAGDRFAVVANEAKAREIAEYRQRLARDKAVARQSGARGSLEQMMNQLQVSGTKEFPLVIKGDVQGSIEAITNALDKLGTDEVRARIVHSGAGGITESDVSLAEASNAAIIGFNVRANKQARDSAEQQGIEIRYYNIIYDLIDDVKAAMSGLLSPERRETFLGNAEILEVFNITKVGKVAGCRVTEGKVERGAGVRLIRDNVVIHEGKLKTLKRFKDEVAEVPSGQECGMAFENYDDIRAGDVIEAFRVEHVSRTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7S_ALKOO
Sequence: MESINFEETLKKLEDVVHKLEVEELSLDDSLKIFEEGIGLYRQCSNELNKIEKKISIIIEENEEFKKVPFPHDEEES
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_AERS4
Sequence: MIQMQSMLGVADNSGARSVMCIKVLGGSHRRYAGIGDIIKVSIKEAIPRGKVKKGDVYNAVVVRTRKGVRRPDGSVIRFDNNAAVLLNNNQQPIGTRIFGPVTRELRNEKFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RRF_CYAP4
Sequence: MKLADVEDHMQKSVEATQRAFNTIRTGRANTSLLDRVTVEYYGAETPLRSLANISTPDSSTIAIQPFDRNSLNLIEKAISMSDLGLTPNNDGTVIRLNIPPLTSDRRKELVKTASKLAEEGKVSIRNVRRDAVDSVKKQGKAGELSEDEVKDLQDKIQKLTDKYIAKVDGLLAEKEKDISTV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAX2_PANTR
Sequence: MFLSPGEGPATEGGGLGPGEEAPKKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLPEVRVQVWFQNRRAKWRRQERLESGSGAVAAPRLPEAPALPFARPPAMSLPLEPWLGPGPPAVPGLPRLLGPGPGLQASFGPHAFAPTFADGFALEEASLRLLAKEHAQAMDRAWPPA
What is the function of this protein?
May be involved in modulating the expression of photoreceptor specific genes.  Binds to the Ret-1 and Bat-1 element within the rhodopsin promoter (By similarity).
What are the official names of this protein?
Retina and anterior neural fold homeobox protein 2, Retina and anterior neural fold homeobox-like protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS5_STAAW
Sequence: MARREEETKEFEERVVTINRVAKVVKGGRRFRFTALVVVGDKNGRVGFGTGKAQEVPEAIKKAVEAAKKDLVVVPRVEGTTPHTITGRYGSGSVFMKPAAPGTGVIAGGPVRAVLELAGITDILSKSLGSNTPINMVRATIDGLQNLKNAEDVAKLRGKTVEELYN
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: HFQ_CALS4
Sequence: MASSKAAINLQDIFLNQVRKEHVPVTVYLINGFQLKGTVKGFDNFTVVLESESKQQLLIYKHAISTISPQKPVIFSGSEKDDKKEE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: SJ643_SCHJA
Sequence: MNTCIQLLILCLVTVINSENSTDHSTENTIENETEDVTKTELLKTIENETENVIETELPETVETEIQTEALNLPQSPEQRYCRSKGQYCSRTYFHRCCGNLVCQLHGFFNGTCVDCLAERKFCIWSSECCSGRCRLFRCRKNTHVKVIHY
What are the official names of this protein?
UPF0506 protein SJCHGC09643.
What is the protein family that this protein belongs to?
Belongs to the UPF0506 family.
What are the subcellular locations of this protein?
Secreted.
Protein: FLGI_BORA1
Sequence: MTQRPFSLLSHLGRICLAAAMLAALPAQAAERLKDLATFQGVRGNQLIGYGLVVGLDGTGDQVRQTPFTQQSLTNMLSQLGITVPAGSNMQLKNVAAVMVTATLPAFARPGQTVDVVVSSMGNAKSLRGGTLLMTPLKGADNSVYAIAQGNVLVGGAGASAGGSSVQINTLNGGRISAGAIVERPVPTSFAQDGLVYLEMNNSDFGTTQNAANAINRQFGAGTAMVMDARVLQLRGPLDPSQMPAFLSQIENLPVTLAPAVAKVIINARTGSVVMNRTVTIEEAAVAHGNLSVIINRQNQVFQPDTPFTDGQTVVAPNTQIEVRQEGGALQRVRTSANLADVVKALNALGATPQDLLAILQAMKAAGALRAELEII
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: HBEAG_HBVA9
Sequence: MQLFHLCLIISCTCPTLQASKLCLGWLWGMDIDPYKEFGASVELLSFLPSDFFPSVRDLLDTSAALYREALESPEHCSPHHTALRQAILCWGELMTLATWVGNNLQDPASRDQVVNYVNTNMGLKIRQLLWFHISCLTFGRQTVLEYLVSFGVWIRTPPPYRPPNAPILSTLPETTVVRRRDRGRSPRRRTPSPRRRRSQSPRRRRSQSRESQC
What is the function of this protein?
May regulate immune response to the intracellular capsid in acting as a T-cell tolerogen, by having an immunoregulatory effect which prevents destruction of infected cells by cytotoxic T-cells.  This immune regulation may predispose to chronicity during perinatal infections and prevent severe liver injury during adult infections.
What are the official names of this protein?
External core antigen, HBeAg, Precore protein, p25.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus precore antigen family.
What are the subcellular locations of this protein?
Secreted. Host nucleus.