PharMolix/UniProtQA huggingface dataset:
Protein: ZAPB_ECO45
Sequence: MTMSLEVFEKLEAKVQQAIDTITLLQMEIEELKEKNNSLSQEVQNAQHQREELERENNHLKEQQNGWQERLQALLGRMEEV
What is the function of this protein?
Non-essential, abundant cell division factor that is required for proper Z-ring formation.  It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle.  Its recruitment to the Z-ring requires functional FtsA or ZipA.
What are the official names of this protein?
Cell division protein ZapB.
What is the protein family that this protein belongs to?
Belongs to the ZapB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the septum at mid-cell, in a FtsZ-like pattern.
Protein: CYSH_AGRFC
Sequence: MEIPDVTMTINSTNASADTASLDATLAGLDLAGRLSFVAGLGGRAVFTTSLGIEDQVITAAIGTHRLPIDVVTLETGRLFKETVDLIDETEERFGIEIRRFRPEQDDIDAYAAKYGLNGFYESVEARHACCHVRKLIPLGKALEGAAFWITGLRRGQSGNRAATPFAEFDAERNLIKINALADWDIEQIRAYVAEENIPVNPLHQRGYPSIGCEPCTRAIKPGEPERAGRWWWENDEKRECGLHVAGAEQTPPVSAIPQR
What is the function of this protein?
Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
What are the official names of this protein?
Adenosine 5'-phosphosulfate reductase, APS reductase, 5'-adenylylsulfate reductase, Thioredoxin-dependent 5'-adenylylsulfate reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPF_BACCN
Sequence: MFRIGQGFDVHEFAEGRPLIIGGITIPYEKGLLGHSDADVLLHTIADACLGAIAAGDIGKHFPDTDPAFKDADSAVLLQKVWEFVREQGYELGNLDCTIIAQKPKMAPHIESMRKRISELLETSIDNINVKATTTEKLGFTGREEGIASQAVVLLQKK
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: RS9_PROM9
Sequence: MNSQIKNKAVYWGTGRRKTSVARVRLIPGNGQIKINGRSGDDYLNFNPLHLNSIKAPLQTLGLENSYDILVNVFGGGLTGQADAIKQGAARALCELSPDNRKPLKTEGHLSRDPRAKERRKYGLKKARKAPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: AROC_NOSS1
Sequence: MGNTFGHLFRITTFGESHGGGVGVVIDGCPPLLEISPEEIQLELDRRRPGQSKITTPRKEADTCEILSGVYEGKTLGTPISILVRNKDTRPQDYDEMAQKYRPSHADATYDAKYGIRNWQGGGRSSARETIGRVAAGAIAKKILRQVANVEVIGYVKRIKDLEGVVDPNTVTLDQVESNIVRCPDGELADRMIELIEQTGRQGDSIGGVVECVARNVPKGLGEPVFDKLEADIAKAVMSLPASKGFEIGSGFAGTLLTGFEHNDEYYIDENGEIRTVTNRSGGIQGGIANGENIILRVAFKPTATIRKEQKTVTREGEETLLAAKGRHDPCVLPRAVPMVEAMVALVLCDHLLRHHGQCKVL
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: UBID_ACTPJ
Sequence: MKYKDLREFLTLLEGQGELVRIKQEIDPYLEMAEISDRTLRKGGPAILFEKPKGYRMPVLCNLFGTPKRVALGMGQEDTHALRELGKLLAFLKEPEPPKGFKELIGQLPQWKQVLNMPSKVLGKADCQQVVLSGDEVDLYKLPIMHCHEGDVAPLVTWGLTVTQGPYKKRQNLGIYRQQLIGKNKLIMRWLSHRGGALDFHEWKEANPDKPFPVSVAIGADPATILAAVTPIPDTLSEYAFAGLLRGQKTEVTKSISNDLEIPASAEIVLEGYIDPNETALEGPYGDHTGYYNEQEYFPVFTVTHITMRRDAIYHSTYTGRPPDEPAVLGEALNEVFIPILQKQFPEIVDFYLPPEGCSYRLAVVTIKKQYAGHAKRVMMGVWSFLRQFMYTKFVIVCDDDVNARDWKDVIWAITTRCDPIRDTTLIDHTPIDYLDFASPIAGLGSKMGIDATNKWPGETSREWGTPIKKDPNVVKLVDEIWDQLGL
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HIS3_BIFLO
Sequence: MTDTTYDNSTELDPRIAARLKRDAKGLVAAVIQQYDTREVLMVGYMNDEALRRTLTTGRVTFWSRSRQEYWRKGDTSGHVQYVKGVSLDCDGDALLVEVDQVGAACHTGKRSCFLEGGPLPVVEGHRPAEQ
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFRP3_CHICK
Sequence: MWRGLPALALAALLLLGRAPAGRAAACEPVRIPLCKPLPWNMTKMPNHLHHSTQANAVLAMEQFEGLLGTNCSPDLLFFLCAMYAPICTIDFQHEPIKPCKSVCERARAGCEPVLIRYRHAWPESLACDELPLYDRGVCISPEAIVTAEGADFPMDSNNGNCRGTGIERCKCKPIKATQKTYLRNNYNYVIRAKVKEVKTKCHDVTAVVEVKEILKSSLVNIPKDTVNLYTNSGCLCPPLSANEEYIIMGYEDEERSRLLLVEGSIAEKWKDRLGKKVKRWDQKLRHLGKGKGEPGQSDSALKTGKPGNARQTRS
What is the function of this protein?
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts.  They have a role in regulating cell growth and differentiation in specific cell types.  SFRP3/FRZB appears to be involved in limb skeletogenesis.  Antagonist of Wnt8 signaling.  Regulates chondrocyte maturation and long bone development.
What are the official names of this protein?
Secreted frizzled-related protein 3, sFRP-3, Frizzled-related protein 1, FrzB-1.
What is the protein family that this protein belongs to?
Belongs to the secreted frizzled-related protein (sFRP) family.
What are the subcellular locations of this protein?
Secreted.
Protein: ECPR_ECOK1
Sequence: MTWQNDYSRDYEVKNHMECQNRSDKYIWSPHDAYFYKGLSELIVDIDRLIYLSLEKIRKDFVFINLNTDSLTEFINRDNEWLSAVKGKQVVLIAARKSEALANYWYYNSNIRGVVYAGLSRDIRKELAYVINGRFLRKDIKKDKITDREMEIIRMTAQGMLPKSIARIENCSVKTVYTHRRNAEAKLYSKLYKLVQ
What is the function of this protein?
Part of the ecpRABCDE operon, which encodes the E. coli common pilus (ECP).  ECP is found in both commensal and pathogenic strains and plays a dual role in early-stage biofilm development and host cell recognition.  Positively regulates the expression of the ecp operon (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator EcpR.
What is the protein family that this protein belongs to?
Belongs to the EcpR/MatA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LFTR_CUPNH
Sequence: MIAWLDPQDPFPPVDEALGPDSEAPGLLAASRDLSPQRLLLAYRQGIFPWYSSGQPVLWWSTDPRMVLAPPALRVSLNLRKTLRRVLRDADWEIRVDDDFLAVMRACATTPRDGQDGTWITDDIIAAYGTLHRNGMAHSVESWYRGERVGGLYGVALGRMFFGESMFAHRTDASKIALAALCAFLGNHGVAMIDCQQETDHLASLGARPIPRAEFVAHVRAATALPAISPWRFDKSVLERWAGTPAAPAG
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_RHOPB
Sequence: MTNERYNARESEPRWQRQWDDNAIFATQNDDPRPKYYVLEMFPYPSGRIHMGHVRNYTMGDVVARTMRARGYNVLHPMGWDAFGMPAENAAMANKVHPKSWTYANIATMKAQLKSMGLSLDWSREFATCDPSYYKHQQRMFIDFLAAGLVERKQSKVNWDPVDNTVLANEQVIDGRGWRSGALVEQRELTQWFFKISKYSEDLLTALDRLDRWPDKVRIMQRNWIGRSEGLLLRFALDTSTTPNHETEVEVFTTRPDTLFGAKFVALSPDHPLAAEAAKSNPALAAFIEECRKTGTAQAEIDTAEKQGFDTGIRAVHPFDPSWQLPVYVANFVLMDYGTGAIFGCPAHDQRDLDFVNKYGLGNLPVVCPEGQDPATFVVTDIAYDGDGRLINSNNGFIALDGMSIADAKEAVAKRLEAIALGNRPVAQRQVNFRLRDWGISRQRYWGCPIPIIHCEVCGVVPVPIKDLPVKLPDDIEFDRPGNPLDRHPTWKHVACPQCGGKARRETDTMDTFVDSSWYFSRFTDPWNEDAPTTRAVVDRMMPVDQYIGGVEHAILHLLYSRFFTRAMQATGHVGFDEPFRGMFTQGMVVHETYRKLDGTFASPAEIRIVADGDNRLASLLDSGQPVEIGPIEKMSKSKRNTVDPDDIIGSYGADTARWFMLSDSPPDRDVIWSEDGVKGASRFVQRVWRLVSAMAPQLPAPGTRLDAANHPAAQALRVAAHRTLSEILAGIDRLRFNTAVAKLYVYVGELEAVLANAPQGGLGGDPVLAAAAREAIDILVLLIAPMMPHLAEECWAAIGHSGLVSEARWPEIETALLVSDSITLPVQVNGKKRGEVTVARDAQNPQIEAAVLALDAVKQALDGKPVRKIIIVPQRIVNVVG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOCS3_BOVIN
Sequence: MVTHSKFPAAGMSRPLDTSLRLKTFSSKSEYQLVVNAVRKLQESGFYWSTVTGGEANLLLSAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGSFSLQSDPRSTQPVPRFDCVLKLVHHYMPAAGAPSFSQPPAEPSSSPSSEVPEQPPAQPLSGNPPRRAYYIYSGGEKIPLVLSRPLSSNVATLQHLCRKTVNGHLDSYEKVTQLPGPIREFLDQYDAPL
What is the function of this protein?
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction.  SOCS3 is involved in negative regulation of cytokines that signal through the JAK/STAT pathway.  Inhibits cytokine signal transduction by binding to tyrosine kinase receptors including IL6ST/gp130, LIF, erythropoietin, insulin, IL12, GCSF and leptin receptors.  Binding to JAK2 inhibits its kinase activity and regulates IL6 signaling.  Suppresses fetal liver erythropoiesis.  Regulates onset and maintenance of allergic responses mediated by T-helper type 2 cells (By similarity).  Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).
What are the official names of this protein?
Suppressor of cytokine signaling 3, SOCS-3.
Protein: 211L_IIV6
Sequence: MEMNQKTAFMGINIKDEGPSNVMIIKALNSSSSLLDIPSFMKVAGIEFDPIMFNHFWQVLVDNGDRLPHVGETTLNWLGYEGVFTKQKEKFINMLKRNQISFKELSYQDNEIQLYPSIQKEMLLLPNESAKTKSKWLLMNPDDFKMAIMGLKTKNSEKIKRYYVTLEKTMKLHSEYALYFHDRKAQEEKERERQRAEDEKRSILGEMSEMRQYMQKMGITLEDTREEVKKVNIQNKDIKAQNEEIKAQNEDLAFDLSDVRDRLIEAAEDRSPKLETKPLRERFVIIKRKDSSFPYYAIRGQDVYVKGRLTHFKNTRYPELKIIFDTNYQPNPRNLYIRFKELKDERFIIAGNNIKTVDSSNKLEKEMLELFEKLNEEKHNIYFFFNFNDF
What are the official names of this protein?
Putative MSV199 domain-containing protein 211L.
Protein: PAP1_YMTV5
Sequence: MNNSITLTLKNYLGRMPTVNEYYMLKSQVRNIQKIMFFNKDIFISLIKKNKKKFFYEIKSSPSEMRLHILEYFMKQQKTSSIGKLYAIIELQTILVSTYTDVLGVLTTKAPYVFPSNVRYEPRSMKKIAHDILTTINVATVSEKVMGRHNVSELVTNVNLLMEEYLRRHNKSCICYGSYSLYLLNPSIEYGDIDIMQTNSRIFLINLAFLIKFITGHNVMLLKVPYLKNYMVLRDDEDKHIIDSFNVRQDTMHSIPKILIDNIYIVDPTFQLLSMIKMFSQVDRLEDLARNQEKATIKLATLLEYVRVKHGIIFNGKVTNMPMPSSFDHEKRIITVDTSRYNFSFKKCFVYLDENSLSSDILNLNADDAIDFENVSNSVFLINDEIMYTYFSNTILMSSKDEIHEISARGVSAHILMYQILTDGDYLIPLSDIVNSLMFKEKIPIFSIIPRDKKTGKHGIINIEKDIITH
What is the function of this protein?
Polymerase that creates the 3'-poly(A) tail of mRNA's.
What are the official names of this protein?
Poly(A) polymerase catalytic subunit, Poly(A) polymerase large subunit, PAP-L.
What is the protein family that this protein belongs to?
Belongs to the poxviridae poly(A) polymerase catalytic subunit family.
Protein: MNTP_ECO57
Sequence: MNITATVLLAFGMSMDAFAASIGKGATLHKPKFSEALRTGLIFGAVETLTPLIGWGMGMLASRFVLEWNHWIAFVLLIFLGGRMIIEGFRGADDEDEEPRRRHGFWLLVTTAIATSLDAMAVGVGLAFLQVNIIATALAIGCATLIMSTLGMMVGRFIGSIIGKKAEILGGLVLIGIGVQILWTHFHG
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Probable manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TGT_PSYWF
Sequence: MQFTLHKTAAGESRARRGTVTVNHGEIRTPAFMPVGTYGTVKGMLPRDIEDIGADIILGNTFHLWLRPGTEVIDKFGGLHQFMNWNKPILTDSGGFQVFSLGAMRKITEEGVAFKSPIDGAKVFLSPEKSMQIQYSLNSDIVMQFDECTPYPATYSEAQKSLELSLRWGQRCVDEHKKLGNTNALFGIVQGSMYEDLRRQSMDGLLEIGFDGYAIGGLSVGEPKEEMISVLNYMPELMPADKPRYLMGVGKPEDILEAVRRGVDMFDCVMPTRNARNGHYFVTGNEDNQGIVRIRNSQYREDQGPLDPECDCYCCQNFSRAYLYHLNKCKEMLGAQLATIHNLRYYQRLMQGIRDAIDEDRFDEFVADFYHRRGQDVPPLELK
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: SECB_YERP3
Sequence: MSEQNNTEMAFQIQRIYTKDISFEAPNAPQVFQQDWQPEVKLDLDTASSQLAEDVYEVVLRVTVTASLGEETAFLCEVQQGGIFSVAGIEGTQLAHCLGAYCPNILFPYARECITSLVSRGTFPQLNLAPVNFDALFMNYLQQQAEGEVEGVEQRQDA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LLDD_SALNS
Sequence: MIISAASDYRAAAQRTLPPFLFHYIDGGAYAEYTLRRNVEDLSQVALRQRVLKNMSDLSLETPLFNETLSMPVALAPVGLCGMYARRGEVQAAAAADAKGIPFTLSTVSVCPIEEVAPTIKRPMWFQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPTPGARYRDAHSGMSGPNAAMRRYWQAVMHPKWAWDVGLNGRPHDLGNISAYLGKPTGLEDYIGWLANNFDPSISWKDLEWIREFWDGPMVIKGILDPEDARDAVRFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGDIAILADSGIRNGLDVVRMIALGADTVLLGRAYLYALATAGKAGVANLLDLIEKEMKVAMTLTGAKSISEISGDSLVQELGKSLPTALAPMSKGDAA
What is the function of this protein?
Catalyzes the conversion of L-lactate to pyruvate.  Is coupled to the respiratory chain.
What are the official names of this protein?
L-lactate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RIMP_NITSB
Sequence: MSLEQEIKQIVESCGAKLYDIETVSDRGKTIYRVTITAPEGVDLQKCVEISNLISPLLDVHPPVSGDYNLEVSSPGVERKLKKPSHFEHSVGEKVRVTKNDGETIEGVLSDFRDHTLTLQTKNGPIEIPLDQITYAKTIFEW
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FSLF_DICDI
Sequence: MKILIIFIIFIISYISGFEIPKGFGIGLVIPDAECLNYIGDPIDQQLCNSKLQNNGDRIYTTTNSQIDSQTNIKKSFEAITFLQDQCKDLLFAQFGICDIYLAPCIEVTLTPLKSISLPQRFCKSVCDRMVSNCPRLEEQMDCSNSFLFPEIGTFYDLSPYGYTIDNGTFAVPCSDPTIFFNQVSSNSSFIEICPSPLLLKNSSDPEYAANKGYSYLSPSNCVLPCPVPNYSNQKWDQLLTMSKILSTISFILSLYNVLTFGIINKKVSDPHKCTCFFSGSIALVNLCDIITYGIGYEELLCPEPGRSAKQQLDPVCGLTGAFFHLGITYCVLWSMTMGLVLYCSVKRQKWFKFNYFLIGNTTFTITTVVIAAATSKFEAGLGSIECWIRDRWYAISLFWIPCGIALLIGSFCIIAVIHEVYKTSKKSISNRNDLLQRELKPLLIVIFISGSFLYLFIFFFDIERKFGGYRSAVEDYVLCLLNGSQEECFTTGPSYVPYFLFYLVIRWFGIIFFLFYGTSNIARKIWVQNKIWKSISSSISPKSTPKSSPKNSDSKINSNSTNNNNMILNDNNDKNLNEKKAVELESIKIN
What are the official names of this protein?
Frizzled and smoothened-like protein F.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor Fz/Smo family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: LGD1_HYPJE
Sequence: MSEVTITGFRSRDVRFPTSLDKTGSDAMNAAGDYSAAYCILETDSAHSGHGMTFTIGRGNDIVCAAINHVADRLKGKKLSSLVADWGKTWRYLVNDSQLRWIGPEKGVIHLALGAVVNAVWDLWAKTLNKPVWRIVADMTPEEYVRCIDFRYITDAITPEEAVAMLREQEAGKAKRIEEALQNRAVPAYTTSAGWLGYGEDKMKQLLRETLAAGYRHFKVKVGGSVEEDRRRLGIAREILGFDKGNVLMVDANQVWSVPEAIDYMKQLSEYKPWFIEEPTSPDDIMGHKAIRDALKPYGIGVATGEMCQNRVMFKQLIMTGAIDICQIDACRLGGVNEVLAVLLMAKKYGVPIVPHSGGVGLPEYTQHLSTIDYVVVSGKLSVLEFVDHLHEHFLHPSVIKDGYYQTPTEAGYSVEMKPESMDKYEYPGKKGVSWWTTDEALPILNGEKI
What is the function of this protein?
Mediates the conversion of L-galactonate to 2-dehydro-3-deoxy-L-galactonate, the second step in D-galacturonate catabolic process.
What are the official names of this protein?
L-galactonate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family.
Protein: FXJ1A_DANRE
Sequence: MLSMSSMDPWPEGSVGLEEEVVTAAAQAERLDTSTPLQCNTSLDSDNLDDSLTSLQWLQEFSILNASTGQHTSPSSHSHLMGSDAPSSPLAGDPASIGMPLTPGKPTAASFCRVPMFSALPSLVAHGHCPDEVDYKSNPHIKPPYSYATLICMAMQASKKTKITLSCIYKWITDNFCYFRHADPTWQNSIRHNLSLNKCFIKVPRQKDEPGKGGFWKIDPQYAERLLNGAYKKRRLPPVQINPALQHRLRMNAQATGVISRNLSVSPESQQLLKDFEEATSADQNWDPRLAEATMLSCWISGKGTNKRKQPYNHRTGKTPRRSSSPLLVMDEQEDLSSLRGNFDWDALLDSALNGELSLNEGSPLSPTPQDEELMIRGTHISPQEAPVENHVLMETQRSGDEDFDEETFLATAFLQSPWSEVDESNRSDFLGSSTVSIDQLFDLSFGGDLSSKIETLL
What is the function of this protein?
Key transcription factor required for motile ciliogenesis.  Activates genes essential for motile cilia formation and function.  Its activity is sufficient for ectopic development of cilia that resemble motile cilia.
What are the official names of this protein?
Forkhead box protein J1-A.
What is the protein family that this protein belongs to?
Belongs to the FOXJ1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GATA_ENDTX
Sequence: MDEILKTRVKDLCEKIRSGQIKSIEIVKACFKRIKETDPKVKAFLKLNEERSLKQAAQSDDKIKTGAECGSLEGVPIGIKDNIMIKGESMTSASKYLENYISPYDAAVIEKLKEAGVIFVGRTNMDEFAMGGSTETSVYQKTANPWNIDYIPGGSSGGSAAAVSSGMVPFALGSDTGGSIRQPAGFCGIVGYKPSYGLISRYGACALASSFDQIGVFSKTVKDASLLTSFIAVGDYRDPVCETGEQTNYAHGIYNPDILKTVRIGIPKQLSNYKADEEITKYFGDAVNKLKLEGAATVEIDVPAYKYVPALYEVIMCAEVSANIATFDGIRYGYRSSNGRNLNDEYAKSRAESLGYEVKKRILFGTYVLGAKNYYRCYHQAQRVRTLLINQITDAYKKCDFIFSPATLQMPVKFGEKLSEECDIFLTAANLAGLPGITVPCTFTSSGMPMGVHFMGSRFSDAKLFQIADAFERISGFDINKYPNL
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: TRAJ3_ECOLX
Sequence: MCALDRRERPLNSQSVNKYILNVQNIYRNSPVPVCVRNKNRKILYANGAFIELFSREDKPLSGESYIRLQVEIFLSSLELECQALGHGSAFCRRFNFHGEIYQIRMENVSFYNDESVVLWQINPFPDYPFFALNQSGSNTNTSDKLTIWNDLSPGTLVVFSFYMLGVGHATIARELGITDRASEDRIKPVKRKIKEFFEHV
What is the function of this protein?
This protein is essential for positively regulating the expression of transfer genes that are involved in the conjugal transfer of DNA between bacterial cells.
What are the official names of this protein?
Protein TraJ.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_LACAC
Sequence: MFVKTGDKVKVIAGKDKGKEGTVLSVNVKKNRVVVKGVNKIKKHQKPSQTNANGGVVESEGSIHASNVKVISKKEDK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: RSSA_MALGO
Sequence: MASKQPAILNPTPEDISLLLAAQTHIGTKNCEKAMLPYVHKRRADGIHLINIGKTWEKLVFAARVLAAVENPADICVISSRTYGHRAVHKFAANTGATAIAGRFTPGSFTNYITRSFKEPRVIVVTDPRVDHQAIRESAYVNIPVIALCDTDAPLRHVDIAIPGNNKGRHSIGLLWWLLCREFLRLRGIVPRTPNGWNVMVDMFFYRDPEEIEREQAEAALAKQAAAANAMQESTIEQVDFAIEGAGAGGVNPSVAANLPAGGEQVDWSADAAQDWAADTGAAPAASSWD
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein S0.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3395_MYCTU
Sequence: MTAAFASDQRLENGAEQLESLRRQMALLSEKVSGGPSRSGDLVPAGPVSLPPGTVGVLSGARSLLLSMVASVTAAGGNAAIVGQPDIGLLAAVEMGADLSRLAVIPDPGTDPVEVAAVLIDGMDLVVLGLGGRRVTRARARAVVARARQKGCTLLVTDGDWQGVSTRLAARVCGYEITPALRGVPTPGLGRISGVRLQINGRGR
What are the official names of this protein?
Uncharacterized protein Rv3395c.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: GP2_MOUSE
Sequence: MVGCDLLWLAAASCVLTLVSPSTIHQGYGRPRNSSNLDLDCGSPDSPSSGICFDPCQNHTVLNDPTRSTENNDSSVAWCDDNLHGWYRFVGDGGVKMPETCVSVFRCHTSAPMWLSGSHPILGDGIVSHTACANWNENCCFWRSEVQVKACSEELGEYHVYKLQGTPECSLRYCTDPSTAPKNCEITCRPEEECVFQNNNWSCVCRQDLHVSDSQSLQPLLDCGDNEIKVKLDKCLLGGMGFKEEIIAYLNDRNCNGTMQDEPNNWVSMTSPVVANYCGNILEKNGTHAIYRNTLSLATDFIIRDFRVNVNFQCAYPLDMSVSLETALQPIVSSLTVDVDGAGEFNVKMALFQDQSYTNPYEGAEVLLPVESILYVGVLLNRGDTSRFKLLLTNCYATPSEDRHDPVKYFIIKNRCPNQRDSTINVRENGVSSESRFSVQMFMFAGNYDLVFLHCEVYLCDSTTEQCQPSCSTNRLRSSRPAIDYNRVLDLGPITKRSAQSSATSKGTPHTTGFLLAWPMFFLPVFLALLF
What is the function of this protein?
Functions as an intestinal M-cell transcytotic receptor specific of type-I-piliated bacteria that participates in the mucosal immune response toward these bacteria.  At the apical membrane of M-cells it binds fimH, a protein of the bacteria type I pilus tip.  Internalizes bound bacteria, like E. coli and S. typhimurium, from the lumen of the intestine and delivers them, through M-cells, to the underlying organized lymphoid follicles where they are captured by antigen-presenting dendritic cells to elicit a mucosal immune response.
What are the official names of this protein?
Pancreatic secretory granule membrane major glycoprotein GP2, Pancreatic zymogen granule membrane protein GP-2.
What are the subcellular locations of this protein?
Zymogen granule membrane; Lipid-anchor, GPI-anchor. Secreted. Cell membrane; Lipid-anchor, GPI-anchor. Apical cell membrane; Lipid-anchor, GPI-anchor. Membrane raft; Lipid-anchor, GPI-anchor. Endosome. Note=Secreted, after cleavage, in the pancreatic juice.
Protein: MIAA_SHESA
Sequence: MGPTASGKTALALELAEKHNCEIISVDSALIYRGMDIGSAKPSAEELARGPHRLIDIRDPAESYSAADFRADALREIEQIISMGKTPVLVGGTMMYFKALLEGLSPLPSADEAIRAEIQAEADANGWEALHEQLREIDPVSAERIHPNDPQRLSRAIEVYRISGKSLTELTQTKSAPLPYDVVQFAIAPRERKVLHELIGQRFRIMLEQGFIDEVAQLKARGDLHLDLPSMRCVGYRQCWQYLDGEFDYDTMVEKAVAATRQLAKRQLTWLRSWPELNWLESGAEGNLVTLMRQCR
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.