PharMolix/UniProtQA huggingface dataset:
Protein: CYB_CHISM
Sequence: MPHQQILMLFGLLPVATNISTWWNFGSMLLACLTLQLLTGFFLAVHYTANINLAFSSIIHITRDVPYGWMMQNLHAIGASMFFICIYIHIARGLYYGSYLNKETWFSGTTLLIMLMATAFFGYVLPWGQMSFWAATVITNLLTAIPYLGSTMTTWLWGGFAINDPTLTRFFALHFILPFGIISLSSLHILLLHEEGSSNPLGTNSDIDKIPFHPYQTYKDMLMLTIMTIMLLTIVSFFPDIFNDPDSFSKANPLVTPQHIKPEWYFLFXYGILRSIPNKLGGALALTMSIMMLLTLPFTHTSKLRSMMFRPFMQLTFWTFTATFLVISWTATKPVEPPFTTISQVAALMYFLFFISNPIMGWLENKIMKL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SYL_CHLTR
Sequence: MRYDPGLIEEKWQKFWENEQVFKAEEDETKTKYYVLDMFPYPSGAGLHVGHLIGYTATDIVARYKRAQGFSVLHPMGWDSFGLPAEQYAIRTGTHPRETTEKNIANFKKQLTAMGFSYDESREFATSDPEYYKWTQKLFLILYEKGLAYMADMAVNYCPELGTVLSNEEIENGFSVDGGYPVERRMLRQWVLRITAFADQLLEGLDELDWPESVKQLQKNWIGKSSGASVNFATEHGVIEVFTTRPDTLIGVSFLALAPEHPLVDLLTSDEQKAVVAQYIKETQSKSERDRISEMKTKSGVFTGSYAKHPVTHKLIPIWIADYVLIGFGSGAVMGVPAHDERDLLFAEQFNLPVVSVLNKEGVCINSCCEGFHLDGLSGEEAKQYVINFLEENHLGAAKIAYKLRDWLFSRQRYWGEPIPIIHFEDGSCRPLRDYELPLLPPEIQDYRPEGVGQGPLAKVREWVQVFDTETQRAGKRETHTMPQWAGSCWYYLRFCDAHNSAAPWAKEKEQYWMPVDLYIGGAEHAVLHLLYARFWHQVFYEAGIVSTPEPFKKLVNQGLVLATSYRIPGKGYIYPEIAKEENGKWVAPSGEELDVRQEKMSKSKLNGVDPQILIDEFGADAVRMYAMFSGPLDKNKLWSNQGVAGCRRFLNRFYEMVSSDRVKEDNNFEGLSLAHKLVQRVTDAIEKLSLNTIPSSFMEFINDFVKLAVYPKSAVEMAVRALAPIAPHISEELWVLLGNSPGVQKSGWPSVLPEYLEGQTVTIVVQVNGKLRARLDIMKDASKEEVLALARESASKYLEGCEVKKAIFVPARLVNFVV
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALLC1_BURPS
Sequence: MALPLSDPNAPEFTRRYVNLADPRLGAQALEASDDFFAPKERMLNPEPAVFIPGKYDDHGKWMDGWETRRKRTTGYDWCVVKLARPGVIKGVDIDTSHFTGNFPPAASIEAAHVPDGAPNEATKWVEIVPATTLQGNSHHYVEARDANAYTHLRVNLYPDGGIARLRVYGQPQLDWAGASRSALFDLAAMENGGYVVAANNQHFGLASNVLLPGRGVNMGDGWETRRRREPGNDWAIVALAQPGVIRKVEIDTAHFKGNYPDRCSIQAAYVQGGTDSSLVTQAMFWPVLLGEQKLQMDKQHAFEAELAALGPVTHVRLNIIPDGGVSRLRVWGTLDK
What are the official names of this protein?
Probable allantoicase 1, Allantoate amidinohydrolase 1.
What is the protein family that this protein belongs to?
Belongs to the allantoicase family.
Protein: DCUP_THEVB
Sequence: MTTPLLLRAARGESVERPPIWLMRQAGRYMKVYRDLRDRYPSFRQRSEIPELAIEISLQPFRAFAPDGVILFSDILTPLPGIGIPFDIVESKGPIIDPPIRTLEQVQHLHPLEPEAACPFIRPILATLRQEVGDRAAVLGFAGAPWTLAAYAIEGKSSKDYIQIKTMAYREPDLLHKFLNHLATAIADYLCYQIDCGAQVVQLFDSWAGQLSRQDYDTFAFPYQKQVIQQVKAVYPDVPIILYINGSAAIVDRMAATGVDIVSLDWTVDLGTIRQQFPPSVGLQGNLDPVILFAPQPVLKERSLAIIEAGRKGKYIFNLGHGVLQGTPEENVAFLFDWVKSLA
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRIM5_PONPY
Sequence: MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSTLDKGERSCPVCRVSYQPKNIRPNRHVANIVEKLREVKLSPEGQKVDHCARHGEKLLLFCKEDGKVICWLCERSQEHRGHHTFLTEEVAQKYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTSVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTKSETEMVQQTQSVRELISDVEHRLQGSVMELLQGVDGVIKRMQNVTLKKPETFPKNQRRVFRAPNLKGMLEVFRELTDVRRYWVDVTVAPNDISYAVISEDMRQVSCPEPQIIYGAQGTTYQTYVNFNYCTGILGSQSITSGKHYWEVDVSKKSAWILGVCAGFQPDAMYNIEQNENYQPQYGYWVIGLEEGVKCSAFQDGSFHNPSAPFIVPLSVIICPDRVGVFLDYEACTVSFFNITNHGFLIYKFSHCSFSQPVFPYLNPRKCRVPMTLCSPSS
What is the function of this protein?
Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses.  Blocks viral replication early in the life cycle, after viral entry but before reverse transcription.  In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates innate immune signaling in response to the retroviral capsid lattice.  Binding to the viral capsid triggers its E3 ubiquitin ligase activity, and in concert with the heterodimeric ubiquitin conjugating enzyme complex UBE2V1-UBE2N (also known as UBC13-UEV1A complex) generates 'Lys-63'-linked polyubiquitin chains, which in turn are catalysts in the autophosphorylation of the MAP3K7/TAK1 complex (includes TAK1, TAB2, and TAB3).  Activation of the MAP3K7/TAK1 complex by autophosphorylation results in the induction and expression of NF-kappa-B and MAPK-responsive inflammatory genes, thereby leading to an innate immune response in the infected cell.  Plays a role in regulating autophagy through activation of autophagy regulator BECN1 by causing its dissociation from its inhibitors BCL2 and TAB2.
What are the official names of this protein?
Tripartite motif-containing protein 5, RING-type E3 ubiquitin transferase TRIM5, TRIM5alpha.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly localizes in cytoplasmic bodies. Localization may be influenced by the coexpression of other TRIM proteins, hence partial nuclear localization is observed in the presence of TRIM22 or TRIM27. In cytoplasmic bodies, colocalizes with proteasomal subunits and SQSTM1.
Protein: AROE_ACTSZ
Sequence: MDNYAVWGNPIKQSKSPQIHKIFAEQTKQCMEYKAILGDPEKFETELLRFFADGAKGCNITAPFKERAYSLADEYSERALTAEACNTLKRLQDGRLYADNTDGAGLVSDLERLGWLKSKQSLLIIGAGGATKGVLLPLLQAQQNITLCNRTLTKARDLADKFAPYGNIQAMKLSEIPVQKFDLVINATSLGLQGKTVDIEPEILRLAGAVYDMQYDKGKDTPFVAWAKALGVQNVHDGFGMLVGQAAHSFYLWRGIMPDIKPLLENDLI
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: T431_STAAN
Sequence: MNYFRYKQFNKDVITVAVGYYLRYTLSYRDISEILRERGVNVHHSTVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWLRKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMAKVIKAFKLKPDCHCTSKYLNNLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIMLAS
What is the function of this protein?
Involved in the transposition of the insertion sequence.
What are the official names of this protein?
Transposase for insertion sequence-like element IS431mec.
Protein: TRPB_HELPJ
Sequence: MNQKAYFGEFGGSFVSELLVPALRELEQAFDTCLKDEEFQKEYFRLLKDFVGRPSPLTLCQNIVSNPKVKLYLKREDLIHGGAHKTNQALGQALLAKKMGKTRIIAETGAGQHGVATAIACALLNLKCVIFMGGKDIKRQEMNVFRMRLLGAEVREVNSGSATLKDAVNEALRDWASSYKDTHYLLGTSAGPHPYPTMVKTFQKMIGDEVKSQILEKENRLPDYVIACVGGGSNAIGIFSAFLNDKEVKLIGVEPAGLGLETNKHGATLNKGRVGILHGNKTYLLQDDEGQIAESHSISAGLDYPGVGPEHSYLKEIGRAVYESASDIEALEAFRLLCQKEGIIPALESSHALAYALKLAQKCAQEKIIVVNLSGRGDKDLSTVYNALKGGLK
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: THIC_DEIRA
Sequence: MSIDHSRISTQPFPASEKRYLGGSLFPEVRVPVRAITLSPTVEAFSGVTRTLPNPPLLVPDTSGAYTDPAVATDLQRGLPHARPWLARSERTEETARFSALADMDGPLPYPHVLTPRRARSESRGGQGITQMQAARRGEITPEMEFVALRENLRQQEQAELAHQHPGESFGASLPRLYTPEFVRDEVARGRAVIPANVNHPELEPTIIGRNFRVKINANLGTSIVTSSIEEEVEKMVWATRWGADTVMDLSTGRHIHQTREWIVRNSPVPIGTVPIYQALEKVDGKAEELTWEVYRDTLIEQAEQGVDYFTIHAGVRLAHVPLTARRRTGIVSRGGSILAKWCLAHHQENFLYTRFAEICEIMAAYDVTFSLGDGLRPGSIEDANDAAQFAELGTLGELTRVAWDHGVQTMIEGPGHVPMQLIRENMTRQLDVCQEAPFYTLGPLTTDIAPGYDHITSAIGAAQIAWYGTAMLCYVTPKEHLGLPDKQDVRDGVITYKIAAHAADLAKGHPGAQARDNAISKARFEFRWQDQFNLALDPEKARALHDETLPADAAKTAHFCSMCGPAFCSMKLSHDIRAGDVLAGLEAKAREFRELGGEIYVEGSDD
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: LRFN2_HUMAN
Sequence: METLLGGLLAFGMAFAVVDACPKYCVCQNLSESLGTLCPSKGLLFVPPDIDRRTVELRLGGNFIIHISRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLGEDTLRGLVNLQHLIVNNNQLGGIADEAFEDFLLTLEDLDLSYNNLHGLPWDSVRRMVNLHQLSLDHNLLDHIAEGTFADLQKLARLDLTSNRLQKLPPDPIFARSQASALTATPFAPPLSFSFGGNPLHCNCELLWLRRLERDDDLETCGSPGGLKGRYFWHVREEEFVCEPPLITQHTHKLLVLEGQAATLKCKAIGDPSPLIHWVAPDDRLVGNSSRTAVYDNGTLDIFITTSQDSGAFTCIAANAAGEATAMVEVSIVQLPHLSNSTSRTAPPKSRLSDITGSSKTSRGGGGSGGGEPPKSPPERAVLVSEVTTTSALVKWSVSKSAPRVKMYQLQYNCSDDEVLIYRMIPASNKAFVVNNLVSGTGYDLCVLAMWDDTATTLTATNIVGCAQFFTKADYPQCQSMHSQILGGTMILVIGGIIVATLLVFIVILMVRYKVCNHEAPSKMAAAVSNVYSQTNGAQPPPPSSAPAGAPPQGPPKVVVRNELLDFTASLARASDSSSSSSLGSGEAAGLGRAPWRIPPSAPRPKPSLDRLMGAFASLDLKSQRKEELLDSRTPAGRGAGTSARGHHSDREPLLGPPAARARSLLPLPLEGKAKRSHSFDMGDFAAAAAGGVVPGGYSPPRKVSNIWTKRSLSVNGMLLPFEESDLVGARGTFGSSEWVMESTV
What is the function of this protein?
Promotes neurite outgrowth in hippocampal neurons.  Enhances the cell surface expression of 2 NMDA receptor subunits GRIN1 and GRIN2A.  May play a role in redistributing DLG4 to the cell periphery (By similarity).
What are the official names of this protein?
Leucine-rich repeat and fibronectin type-III domain-containing protein 2, Synaptic adhesion-like molecule 1.
What is the protein family that this protein belongs to?
Belongs to the LRFN family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Synapse. Postsynaptic cell membrane.
Protein: PGK_CLOBH
Sequence: MNYNKKSIEDIDVKGKKVLVRCDFNVPLNEGKITDENRLVGALPTIKYLMEKGAKIILCSHMGKPKGEPKKELSLLPVAKRLSEMLNKEVIFADDDNVVGENAKKAVEDMKDGDVVLLQNTRYRKEETKNEEVFSKELASLADVFVNDAFGTAHRAHCSTVGVTNYLKEAACGYLIQKELKFLGNAVEKPERPFVAILGGAKVSDKINVINNLLDKVDTLIIGGGMGYTFLKAQGYTIGNSLVEEDKVEYSKEMIDKAKEKGVNLLLPIDNVVADKFDKDASPVITEDQNIGEGYMGLDIGPKTAKIYSDAIKSAKTVVWNGPMGVFEFKSFANGTIEVAKAMADSDAVTIIGGGDSAAAVNILGFGDKMTHISTGGGASLEFLEGKELPGIAALNDK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPG_MYCBP
Sequence: MNAHVEQLEFQAEARQLLDLMVHSVYSNKDAFLRELISNASDALDKLRIEALRNKDLEVDTSDLHIEIDADKAARTLTVRDNGIGMAREEVVDLIGTLAKSGTAELRAQLREAKNAAASEELIGQFGIGFYSSFMVADKVQLLTRKAGESAATRWESSGEGTYTIESVEDAPQGTSVTLHLKPEDAEDDLHDYTSEWKIRNLVKKYSDFIAWPIRMDVERRTPASQEEGGEGGEETVTIETETLNSMKALWARPKEEVSEQEYKEFYKHVAHAWDDPLEIIAMKAEGTFEYQALLFIPSHAPFDLFDRDAHVGIQLYVKRVFIMGDCDQLMPEYLRFVKGVVDAQDMSLNVSREILQQDRQIKAIRRRLTKKVLSTIKDVQSSRPEDYRTFWTQFGRVLKEGLLSDIDNRETLLGISSFVSTYSEEEPTTLAEYVERMKDGQQQIFYATGETRQQLLKSPHLEAFKAKGYEVLLLTDPVDEVWVGMVPEFDGKPLQSVAKGEVDLSSEEDTSEAEREERQKEFADLLTWLQETLSDHVKEVRLSTRLTESPACLITDAFGMTPALARIYRASGQEVPVGKRILELNPSHPLVTGLRQAHQDRADDAEKSLAETAELLYGTALLAEGGALEDPARFAELLAERLARTL
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3252_KLEP3
Sequence: MTWFIDRRLNGKNKSAVNRQRFLRRYKAQIKQSISEAINKRSVTDIESGESVSIPTDDINEPMFHQGRGGLRNRVHPGNDHFVQNDRIERPQGGGGGGGGDQGQASADGEGKDEFVFQISKDEYLDLLFEDLALPNLKKNQHRQLNEFKTHRAGFTSNGVPANISVVRSLQNSLARRTAMTAGKRRELRALEEDLETISRSEPVQLLEEERLRKEIAELRAKIERVPFIDTFDLRYKNYEKRPEPSSQAVMFCLMDVSGSMDQATKDMAKRFYILLYLFLSRTYKNVDVVYIRHHTQAKEVDEHEFFYSQETGGTIVSSALKLMDEVVQARYDPAQWNIYAAQASDGDNWADDSPLCHELLAKKILPVVRYYSYIEITRRAHQTLWREYEHLQATFDNFAMQHIRDQEDIYPVFRELFHKQSSKSEA
What are the official names of this protein?
UPF0229 protein KPK_3252.
What is the protein family that this protein belongs to?
Belongs to the UPF0229 family.
Protein: DP2L_METM5
Sequence: MLHVSASKGMTEYFKNILDNVKNLYDLAEGCRKSGYDVTDHVEIPLAKDMADRVEGIVGPKNVAERIRELVSDLGKEPAALEIAKEIVEGKFGEFGREVGAEQAVRTALAVITEGIVAAPLEGIAHVKIKKNNDGGEYLAIYFAGPIRSAGGTAQALAVLVGDYVRKNMGLDKFKPTDDEVERYGEEVDLYQSEVTTFQYQPKAEEIRVAVRNISVEITGEATDDVEVSGHRDLPRIETNQIRGGALLALVEGVLLKAPKILRHVDKLGIEGWDWLKELKSKKEELVEEIEEENDEFNYEEEEDLSQYEDYEVEAVTKFIGEVIAGRPVFSHPSKKGGFRLRYGRSRNTGFATDGFHPAIMYLVDDFMAVGTQLKTERPGKATCVVPVDSIEGPIVKLNDKSVLKIDTVEKAKQYRDDVEEILFLGDILVNYGDFLENNHTILPSSWCTEWYEKILKSENLEYTKEFIENPDQKEVVKYAKLTNTPLHPKYTYFWHDISKDNINVLRNWIIGGRYNESNDSWGLTYDPEDPEISIVKRYLELIGCPHTVVDEKVEIFEYYPLLYSLGYDFDEKQDVVEDIEEKLQNTKNNMHFINTIAPFEIRRNAYIYVGARMGRPEKAASRKMKPPVNGLFPIGNAGALVRLINKAVDEGKTDEIEISNVKCSCGNVSLYRTCPFCGSSVEPSGPSRIKLPIKEYWYKALENLKINKAGDVKCIKGMTSKDKIIEPLEKAILRAKNDIFVFKDGTTRFDCTDVPVTHFRPVEIHGDIEKLKSLGYLKDIHGNPLENENQVLELNVQDVIVPESCMDYFLNVSKFIDDLLEKYYKKDRFYNVNKREELVGHLIIGMAPHTSAGMVGRIIGYSKANVGYAHPYFHASKRRNCDGDEDAFFLLLDAFMNFSKRFLPDKRGGQMDAPLVLTTILDPKEVDGEVHNMDSMWEYPLEFYEKSLEGIAPKEIKKIMETVEDRLDKESQYEGIGYTHETLKIDEGPLVCAYKTLGSMMEKTSAQLAVAKKIRATDERDVAEKVIQSHFVPDLIGNLRAFSRQGVRCKCGAKYRRMPLKGICRKCGSRLILTVSKGAVEKYMDVSQTMAEKYNASDYIKQRLEIIRSGIDSLFVNDKRKQVKIEDFFK
What is the function of this protein?
Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction.  Has a template-primer preference which is characteristic of a replicative DNA polymerase (By similarity).
What are the official names of this protein?
DNA polymerase II large subunit, Pol II, Exodeoxyribonuclease large subunit.
What is the protein family that this protein belongs to?
Belongs to the archaeal DNA polymerase II family.
Protein: GPSB_STRZJ
Sequence: MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAALVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQILDNSDF
What is the function of this protein?
Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome.  Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression.  Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed.  Also contributes to the recruitment of PBP1 to the division complex.  Not essential for septum formation.
What are the official names of this protein?
Cell cycle protein GpsB, Guiding PBP1-shuttling protein.
What is the protein family that this protein belongs to?
Belongs to the GpsB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Shuttles between the lateral wall and the division site in a cell cycle-dependent manner.
Protein: CCD57_HUMAN
Sequence: MLPLGSEPALNELLLRKEEEWRALQAHRTQLQEAALQDTRSQLEEAQGKLRCLQEDFVYNLQVLEERDLELERYDAAFAQAREWEEARRAEVSELKIEAAKLRQALAREARKVEELQQQQQLAFQEHRLELERVHSDKNGEIDHHREQYENLKWTLERKLEELDGELALQRQELLLEFESKMRKREHEFRLQADNMSNTALSRELKVKLLHKELEALKEAGAKAAESLQRAEATNAELERKLQSRAGELQDLEAMSRARVKDLEDKLHSVQLTRKKEEETFKRKHEELDRLAREKDAVLVAVKGAHVEQLQELQTRVLELQAHCETLEAQLRRAEWRQADTAKEKDAAIDQLREDASTVKSAWDAQIAQLSKEMVSRDLQIQTLQEEEVKLKAQVARSQQDIERYKQQLSLAVERERSLERDQVQLGLDWQRRCDDIERDQIQKSEALIQGLSMAKSQVAAKLQETEQALQEQEVVLKAVTLERDQAVQALRMHGLPRPGAQMLLRQHEEEISKDFPSSEIQRLREQNTSLRNAIAQMRKEMEALSHQIPPPIQTAAESTDANQPDPEAGGDAATPDYVLALEAEIRTLKHKFKTLEKHLEDVLDPLKMSSPHAESQPSVRTSTETTGGSAQAGQAGGSVQAGQAGGSVQAGPVSSGLALRKLGDRVQLLNLLVTRLRQKVLREPLEPAALQRELPREVDQVHLEVLELRKQVAELGKHLRIAQHGGAEPSGRKQPPASDAVALGREDAKSAEDEAPSRHLGKHQPRSAQVGSRLDALQGPKTQHSIHTVTCKSPRQKEDRSPKPPQAPQHPEEHGRQSHSSSSFASGTLQDMWRLLDLGSSPSGVTSQGDSTPELPAPPAADRRPVKMQAGIATPGMKTAAQAKAKTTGASRSHPAKAKGCQRPPKIRNYNIMD
What is the function of this protein?
Pleiotropic regulator of centriole duplication, mitosis, and ciliogenesis.  Critical interface between centrosome and microtubule-mediated cellular processes.  Centriole duplication protein required for recruitment of CEP63, CEP152, and PLK4 to the centrosome.  Independent of its centrosomal targeting, localizes to and interacts with microtubules and regulates microtubule nucleation, stability, and mitotic progression.
What are the official names of this protein?
Coiled-coil domain-containing protein 57.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle. Note=Localizes to resolvable rings at the proximal end of centrioles (PubMed:32402286). In mitotic cells, localizes to spindle microtubules during metaphase (PubMed:32402286).
Protein: RL11_CAMC5
Sequence: MAKKVIGEIKLQIAATKANPSPPVGPALGQKGVNIMEFCKAFNEKTKDMVGFNIPVVITVYADKSFTFITKQPPATDLIKKAAGIAKGTDNPLKNKVGKLTKAQVLEIVEKKLVDLNTNDKEQAAKIIAGSARSMGVEIVD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: LPHN_DROGR
Sequence: MYLKNHTLGLRTKASQGAPLAKAAQSLLQLKKLDCVPPKYQTAYACEGKKLTIECEPGDLINLIRANYGRFSITICNDHGNVEWSVNCMFPKSLTVLNSKCSHKQSCSVLAATSMFGDPCPGTHKYLEAHYQCISAAQTSTTTNRPSPPPWVLSNGPPIFGNGSGLIQPTPQPPPRLPTLPGVVGIHGINGVPPTHATPSSSTAMLPGGRLKGVTSATTKHPGGRHDGLRPPPQLHHHHHHTDDTAPTKSSSGSAGNVTAPSNTRILTGVGGGGSDDGTLLTTKSSPNRTPGTAASAANNNSLGIGGTAPGSGGGVVRTINNINLNAAGMGAEDESKLFCGPTHARNLFWNMTRVGDVNVQPCPGGAAGIAKWRCVLMKRVPDAGYDEYDDEMPVASSTTPMPPPSSAGGDCLHNSSSCEPPVSMAHKVNQNQRLRNFEPTWHPLTPDLTQCRSLWLNSLEMRVNQQDSSLISIANDLSEVTSSKTLYGGDMLVTTKIIQRMSEKMLHDKGTFPDQRQREAIIMELLHGVVKTGSNLLDESQLSSWLDLNQEDQMRVATSLLTGLEYNAFLLADTIIRERNVVQKVKNILLSVRVLETKTIQGNVVFPDSDQWPLSSDRIELPRTALKENSEGGLVRIVFAAFDRLESILKPSYDHFDLKSARSYVRNTAILSNDSDTNAGEMQQRVRILNSKVISASLGKGRHIQLSQPIKLVLKHLKTENVSNPTCVFWNYIDHAWSANGCSLESTNRTHSVCSCNHLTNFAILMDVVDEHQHSLFTMFDGNMRIFIYISVAICVVFIIIALLTLKLFNGVFVKSARTSIYSSIYICLLAIELLFLLGIEQTETSIFCGFITVFLHCAILSGTAWFCYEAFHSYSTLTSDELLLEVDQTPKVNCYYLLSYGLSLSVVAISLGINPSTYTLRNDYCVLMEANALFYVTFVAPILIFFVAAISYTFLSWIIMRRKSRTALKTKEHTRLANVRFDIRCSFVFLLLLSADWCCAYFYLRGAKLDEDVAAIYGYCFVCFNTLMGLYIFVFHCIQNEKIRREYRKYVRQHAWLPKCLRCSKTSISSGIVSGNGGPGGVSGGVATNSAGTLSKSKSKLPLGSSDDGHDEEQPHQQQHQHDQPANEDAIIMGAGSDCELSEAQQRRTLKSGLLAGSLQPVTPVGAVVLERGTLRSTGMASVGHASPTSSAGSTHLIFAHKHQQQLQQQPGESYYHQPDYYSWKHPQAGGQREYYNNTGVPGGGGGVGVGGASPQQSHEVFYWTQKHNNQHGKKKRGGGAGAVPASPSGSLHSRVTPASQVLFYPSYKKTSGMKQPPPSAQQAYPHYAEALDPPNNAAYYQQQLQQQQQLRQQRQQQQQQQLSSDEEQAHLLHLQHQQRRAGGQQQLPAPPPHMAQYQQELLAQQQRQQYRNKHSNCDLSQGIGLGMNMGMGQGLGGDAYYNQGGGGSSNGGGVGGDGPVYEEILSNRNSDAQHYEVGDFDVDEVYNNSVGTGVFNSMRAAVAAGGSRYGGGSLSGGSVTSRNQQQQLQAKQKQPPRRCAADDDDDDDDDDDEYDDEVTAAEQLHDSVCDDEDNESDMDDDDTHGLPPQSDERMRRLMALQDEDFKRRFQRQQRKNGLPLDYGAPPQTSAGATIAHPIEHNGAVFGVSGGVGEGSMRGAYRQQQQQLNAKSPSARLAVNELFGHGNAGPPLPPANQTPAQKRQQLQKLSPQSTTSSSSHTSHSNLQQHSAPTHHHLQHQQPQLHHHQQQQQARNLSAMLDENNTVRCYLEPLAK
What are the official names of this protein?
Latrophilin Cirl.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ARI2_CAEEL
Sequence: MDDEDMSCTSGDDYAGYGDEDYYNEADVDAADDVAVTPTHSEEADYECLSVNQVERVFIDGVNSLVSRISINEKFARILLQANHWDVDKIARLVRNDRNDFLRKCHIDAKPEPKRKLSSTQSVLAKGYCSVCAMDGYTELPHLTCGHCFCEHCWKSHVESRLSEGVASRIECMESECEVYAPSEFVLSIIKNSPVIKLKYERFLLRDMVNSHPHLKFCVGNECPVIIRSTEVKPKRVTCMQCHTSFCVKCGADYHAPTSCETIKQWMTKCADDSETANYISAHTKDCPQCHSCIEKAGGCNHIQCTRCRHHFCWMCFGDWKSHGSEYYECSRYKENPSVAAEANHVKARRALEKYLHYFERFENHSKSLKMEEELRDKIRKKIDDKVNEHNGTWIDWQYLHKSVSLLTKCRYTLQYTYPFAYFLSATPRKNLFEYQQAQLEKEVEELAWAVERADGTARGALEAHMHRAEHKRQTLLHDFFF
What is the function of this protein?
Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBC-2/UBE2L3, and then transfers it to substrates.
What are the official names of this protein?
Potential E3 ubiquitin-protein ligase ariadne-2, Protein ariadne-2, Ari-2, RING-type E3 ubiquitin transferase ariadne-2.
What is the protein family that this protein belongs to?
Belongs to the RBR family. Ariadne subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: HBA3_PLEWA
Sequence: MVLSAEEKALVVGLCGKISGHCDALGGEALDRLFASFGQTRTYFSHFDLSPGSADVKRHGGKVLSAIGEAAKHIDSMDQALSKLSDLHAYNLRVDPGNFQLLSHCIQAVLAAHFPADFTPQCQAAWDKFLAAVSAVLTSKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin larval subunit alpha, Alpha-globin, larval, Hemoglobin alpha-chain, larval.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: MCDP_APIME
Sequence: MISMLRCTFFFLSVILITSYFVTPTMSIKCNCKRHVIKPHICRKICGKNG
What is the function of this protein?
Potent anti-inflammatory agent.  At low concentrations, mediates the degranulation of mast cells thus evoking an inflammatory response.  Also acts as a neurotoxin capable of blocking a class of voltage-gated potassium channels.
What are the official names of this protein?
Mast cell degranulating peptide, MCD peptide, MCDP, Peptide 401.
What are the subcellular locations of this protein?
Secreted.
Protein: A18_VACCT
Sequence: MSLLKMEYNLYAELKKMTCGQPLSLFNEDGDFVEVEPGSSFKFLIPKGFYASPSVKTSLVFETLTTTDNKITSINPTNAPKLYPLQRKVVSEVVSNMRKMIESKRPLYITLHLACGFGKTITTCYLMATHGRKTVICVPNKMLIHQWKTQVEAVGLEHKISIDGVSSLLKELKTQSPDVLIVVSRHLTNDAFCKYINKHYDLFILDESHTYNLMNNTAVTRFLAYYPPMMCYFLTATPRPANRIYCNSIINIAKLSDLKKTIYAVDSFFEPYSTDNIRHMVKRLDGPSNKYHIYTEKLLSVDEPRNQLILNTLVEEFKSGTINRILVITKLREHMVLFYKRLLDLFGPEVVFIGDAQNRRTPDMVKSIKELNRFIFVSTLFYSGTGLDIPSLDSLFICSAVINNMQIEQLLGRVCRETELLDRTVYVFPNTSIKEIKYMIGNFMQRIISLSVDKLGFKQKSYRKHQESDPTSVCTTSSREERVLNRIFNSQNR
What is the function of this protein?
DNA helicase which seems to act as a postreplicative transcription termination factor.  Involved in ATP-dependent release of nascent RNA.  Forms a stable complex with single-stranded DNA, and to a lesser extent RNA (By similarity).
What are the official names of this protein?
Transcript termination protein A18, 56 kDa abortive late protein.
What is the protein family that this protein belongs to?
Belongs to the helicase family. Poxviruses subfamily.
What are the subcellular locations of this protein?
Virion. Note=Localizes to the virion core.
Protein: RL13_COLP3
Sequence: MKTFVAKPASVQREWFLVDAEDKTLGRIATEIATRLRGKHKAEYTPHVDTGDYIVVINAEKVRVTGNKAKGKIYYSHTEFPGGLKQISFEKLIEKAPTRVLEFAVKGMLPKGPLGREMFRKLKVYAGPEHAHTAQQPQLLEL
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.