PharMolix/UniProtQA huggingface dataset:
Protein: SYP_BDEBA
Sequence: MADTAITPTRSQNYPEWYQQVIVAADMAENSPVRGCMVIKPWGYAVWENMQGVLDRMFKDTGHVNAYFPLLIPLSFLEKEAAHVEGFAKECAVVTHHRLKGDGNGKLIPDGELEEPLIIRPTSETIIGHQFAKWVKSYRDLPILVNQWCNVMRWEMRTRMFLRTAEFLWQEGHTVHATAKEAQEETLQMLNVYSEFAEQYMAMPVIKGMKTPDERFPGAVDTYTIEALMQDKKALQAGTSHFLGQNFAKASEIKYLSAEGKEEFAWTTSWGVSTRLIGGLIMTHSDDNGFVVPPRLAPLHVVIIPIYRNDEERAQVLDYVKALEKDLKAQNYVGSSVRVKIDDRDMRGGEKAWQYIKQGVPVRVEVGPRDMAKGEVFVGRRDRGPKEKASMERNAFVANITNLLQEMQDGLFERAKQMRDESIKTITNLQDFEKYFSGGENTAPGFAKVPWCEAGMGHELLAQLKVTPRCMPLDQEPVQGNCIFSGKPATKWVLFAKSY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUON_RHOOB
Sequence: MSTSEFVLAQSATVPAPDIEYGQLSPMLIVFGVAVAGVLVEAFLPRRGRYSSHLVLALGGLTAAFVAVVLLAGTRDSVVGGAVAVDGPTLFLQGTILLISIPAILIIAERSVDSGVAAATAEVTAVRGAEPEGGTDAFTPQAFAVPGSVAEREATRNAPGHTEVFPLTLFAVGGMLLFPASNDLLTMFVALEVLSLPLYLLCGLARRRRLLSQEAALKYFLLGAFSSAFFLFGVALLYGYAGTVALPGIADALARGTEDRTLALIGTALLSVGLLFKIGAVPFHSWIPDVYQGAPTPITAFMAAATKVAAVGAMLRIFYVALPDLRADWRPVMWGVAILTMVVGAVMAVTQNDVKRMLAYSSVAHAGFILTGLVAANRAGLSSTMFYLLAYGFSTLGAFAVVTLVRDSRGEATDLSRWAGLGRRSPLVGGVFALFLLAFAGIPLTSGFVSKFAVFQAALEGGAVPLVLVGVVSSAIAAFFYVRVIVLMFFSEPQSDAPTIVVPSMFTAAAIAVGVVVTVVLGILPQGALDLADQAAVFFR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FHCB_METEA
Sequence: MAAWVKGGAADVDAAVEAAADLLAASRVPVLAGLSAEVSALRAAYRLAETLGASLDPVSGPSVYAELGALSAGGAMSTTRAETIGRADVILIVGNRPWDGELIAEIAAAAPSRGRAAGSERALLSLGGPQNGAIRHVAYAADAGGLTISLGHLRAFAKGHLAGEAAFADLAKRLFAAQYGVIVYDPEEVGELGAEMLQGLIRDLNESTRFFALTLADPFQGRAAVQLSAWTTGQAPRVGFGRHQPEHDSWRFDSARQIAAGEADAALWLASLPAPRPAWLGSLPTIAIVGEGSQEAAGETAEVVITVGVPGQSVGGALWNDRRGVIAYAEASDPAKTPAETETAAGVLTRIRDRLIEKGVSC
What is the function of this protein?
Involved in the transformation of 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) and formate via the formylmethanofuran (formyl-MFR).
What are the official names of this protein?
Formyltransferase/hydrolase complex Fhc subunit B.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UL19_HCMVA
Sequence: MTSNALYELFRRRLPRAPVNTVMFLTRRTRDGFCGRLTSIATNSHYTMFVLDHGSVRIERPSQSEVDCASLMETLKRIRLRNSWVASEDELDVSRGDA
What are the official names of this protein?
Uncharacterized protein UL19.
What is the protein family that this protein belongs to?
Belongs to the HHV-5 UL19 protein family.
Protein: NDK_HAEIG
Sequence: MTERTFSIIKPDAVKRNLIGAILTRFEQNGFKIIASKMVRLTREQAEGFYAEHQGKEFFAPLVEYMMSSPIVVSVLEKENAVKDYRTLIGTTNPETAEEGTIRKDFALSQRENSVHGSDSIENANREIAYFFTDCEIFER
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLF1_CANGA
Sequence: MTEIPAKQITDNDILKDVYKSQNKQFSIDAIDILDLEELKDVQRRKRTEFEGYLKRNRLDVKQWMRYAVFEIEQHDMRRARSIFERALRVHISYVPLWIRYIESELKLGYINHARNILERAITKLPRVDKLWYKYLIVEESLAHFDIVRNLFQKWCSLEPAAHVWDSFTDFEVRQERYEDVRNIYSKYVLIHPQFSTWRKWINFEVRYGSTKTVRSVYSLALDALIAYSESRNELVDDCINLIVEFSKWEALQKEYIRSKSLLEIAIQKWPKSNTLNNALLQFEREHGTAETLENTIILNRKKHYEDILNEKVYDYDTWLLYLQLLENNYPKLVMEAFSNVLNAAIPTSRTKDKYWKQYILIWIKYLTFLELTINDIPLCGQKFEELIHNIIPNDDFTFSKIWILYAEFEIRQDNLEKARSILGRSLGLCPKRKTFKYYIDLETKLREFDRVRILYENFLKFDPLNLDTWRAYVEFEDSLGDEVRVRSVCMIPIQNNIGLFSKSFQLHLLEILIDYEMEYQNFDNIEPLLKKQVELSNFTVEAWTDYAMKKLTVPTEEQVQNFQIMKEERLKDSSALDEQEIEFEFEITDNNKDNARDVFERALNYFKEIKRDEDRARILQSYVDFEGQYGDISSRQRIEKRLPSIVNGIKDIDGLKTQNITYTFPDDENKSNIDTSNILALAHKWKESQEAKSR
What is the function of this protein?
Involved in pre-mRNA splicing and cell cycle progression.  Required for the spliceosome assembly and initiation of the DNA replication (By similarity).
What are the official names of this protein?
Pre-mRNA-splicing factor CLF1.
What is the protein family that this protein belongs to?
Belongs to the crooked-neck family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PURT_HAEDU
Sequence: MTTMGTPLTPNATKVMMLGSGELGKEVVIELQRLGVEVIAVDRYANAPAQQVAHRAYTISMLDDDALRAVVEQEKPDFIVPEVEAIATETLVELEQKGYQVVPTAKATQLTMNREGIRRLAAEELGLPTSPYRFVDNFADFQQAVLAVGVPCVVKPIMSSSGHGQSIIKSLDQIQQAWDYSQAGGRAGGGRVIVEGFIKFDYEITLLTVRHINGTSFLAPIGHRQQNGDYRESWQPQAMSEVALQKAQQIAERITTALGGRGIFGVELFVCGDDIIFNEVSPRPHDTGMVTMASQELSQFALHARAILGLPIPHIEQFGPAASKAIVVEGKSNNVMFVGLDKVLEERGTHIRLFGKAEVNGHRRLGVILARDESTDKALAKVERAYANLTVKL
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: LGT_WOLPP
Sequence: MSLSPVIFSIGPVSIYWYSLAYVLGIVFAYWYLHKLDNQKIFTKNFYDSLLTAVIIGIILGGRLGYVLIYDPVLYISNPIEILKTWEGGMSFHGGAIGVLLAVIISCRRHNIPIFYTLDLISCGVPIGLLLGRIGNFINGELFGRVTTMPWGMVFPESGDNLLRHPSQLYEAFFEGALLFVVVNSLFYLNKMRLYYGATTGVAVMLYGVARFMVEFFREPDYQIGYLWFNLTMGQLLSIPMILLGMLIYLGALNFRFNTKSIQ
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: COMD_METJA
Sequence: MRGSLAIYNALKDSNIDFICSVPCANLKNLLKLIEEDKNIINIPATREEEAFGICAGAYLAGKKTAILMQNSGIGNSINAIASLYKTFQIPTLLIISHRGDLKEQIPAQIPMGRWIEKLLDVCEIPTYKPKTPEEAYKLIKYASSYMYKISYPVALLFDALYWEYDLEK
What is the function of this protein?
Involved in the biosynthesis of the coenzyme M (2-mercaptoethanesulfonic acid).  Catalyzes the decarboxylation of sulfopyruvate to sulfoacetaldehyde.
What are the official names of this protein?
Sulfopyruvate decarboxylase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ComD family.
Protein: RAPA_ECO57
Sequence: MPFTLGQRWISDTESELGLGTVVAVDARTVTLLFPSTGENRLYARSDSPVTRVMFNPGDTITSHDGWQMQVEEVKEENGLLTYIGTRLDTEESGVALREVFLDSKLVFSKPQDRLFAGQIDRMDRFALRYRARKYSSEQFRMPYSGLRGQRTSLIPHQLNIAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIIVPETLQHQWLVEMLRRFNLRFALFDDERYAEAQHDAYNPFDTEQLVICSLDFARRSKQRLEHLCEAEWDLLVVDEAHHLVWSEDAPSREYQAIEQLAEHVPGVLLLTATPEQLGMESHFARLRLLDPNRFHDFAQFVEEQKNYRPVADAVAMLLAGNKLSNDELNMLGEMIGEQDIEPLLQAANSDSEDAQSARQELVSMLMDRHGTSRVLFRNTRNGVKGFPKRELHTIKLPLPTQYQTAIKVSGIMGARKSAEDRARDMLYPERIYQEFEGDNATWWNFDPRVEWLMGYLTSHRSQKVLVICAKAATALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIGSEGRNFQFASHMVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRWYHEGLDAFEHTCPTGRTIYDSVYNDLINYLASPDQTEGFDDLIKNCREQHEALKAQLEQGRDRLLEIHSNGGEKAQALAESIEEQDDDTNLIAFAMNLFDIIGINQDDRGDNMIVLTPSDHMLVPDFPGLSEDGITITFDREVALAREDAQFITWEHPLIRNGLDLILSGDTGSSTISLLKNKALPVGTLLVELIYVVEAQAPKQLQLNRFLPPTPVRMLLDKNGNNLAAQVEFETFNRQLNAVNRHTGSKLVNAVQQDVHAILQLGEAQIEKSARALIDAARNEADEKLSAELSRLEALRAVNPNIRDDELTAIESNRQQVMESLDQAGWRLDALRLIVVTHQ
What is the function of this protein?
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations.  Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA.  Does not activate transcription on linear DNA.  Probably not involved in DNA repair.
What are the official names of this protein?
RNA polymerase-associated protein RapA, ATP-dependent helicase HepA.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
Protein: ISPF_YERPP
Sequence: MRIGHGFDVHKFGENGSGPLIIGGVRIPYEKGLLAHSDGDVALHAATDALLGAAALGDIGKLFPDTDPAFKGADSRGLLREAYRRILAKGYKLGNLDITIIAQAPKMAPHIPQMRVNLAEDLQCHMDDINVKATTTEQLGFTGRGEGIACEAVVLLVNVEQG
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: IMQG_ASPFN
Sequence: MTATTTTTSQIFVSEDYNQDPNWYAVDNYTLSHLQPPTRPNHASLHQTLENSAKRGLEDISAFPTQAKFMALQCQLGGVKHALEVGTLGGYTAIYIASLNPDIRIVSIEIDPKSAEVAKENIAAAGYQDRIEVLVGAAIDLLPILQAKVENGEQERFGFTFIDANKDNGWDYFDYAVKMSRPRASIIVDNVVRAGKLVQEDYIKNDINVRGSRRTVENVGKDDRVDAVVLQTLSEKSYDGFLMAVVK
What is the function of this protein?
O-methyltransferase; part of the gene cluster that mediates the biosynthesis of imizoquins A to D, tripeptide-derived alkaloids that serve a protective role against oxidative stress that are essential for normal germination (PubMed:29182847).  ImqB is a canonical three-module NRPS that assembles the tripeptide backbone of the imizoquins via condensation of Trp, Tyr, and Leu-derived precursors (PubMed:29182847).  N-methylation by imqF and phenol oxidation by imqC, followed by cyclization via the FAD-dependent oxidase imqH carry out the three-step transformation of L-tyrosine into tetrahydroisoquinoline (PubMed:29182847).  Importantly, this sequence requires the presence of a free amine in the tyrosine moiety, indicating that isoquinoline formation occurs prior to peptide bond formation (PubMed:29182847).  The imidazolidin-4-one ring of imizoquins could form following additional oxidation of the methyl-derived bridgehead carbon by imqH (PubMed:29182847).  Lastly, O-methylation by imqG and leucine hydroxylation by imqE complete biosynthesis of the imizoquins (PubMed:29182847).
What are the official names of this protein?
O-methyltransferase imqG, Imizoquin biosynthesis cluster protein G.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. CCoAMT subfamily.
Protein: 3SAFD_NAJAT
Sequence: LKCKKLVPLFSKTCPPGKNLCYKMFMVAAPKVPVKRGCINVCPKSSLLVKYVCCNTDKCN
What is the function of this protein?
Shows cytolytic activity on many different cells by forming pore in lipid membranes.  In vivo, increases heart rate or kills the animal by cardiac arrest.  In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 (KCNIP1) in a calcium-independent manner, and binds to integrin alpha-V/beta-3 (ITGAV/ITGB3) with moderate affinity.
What are the official names of this protein?
Cytotoxin SP15d.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type IA cytotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: NU2M_DIDVI
Sequence: MSPYVLTIMSFSLLLGTTMTLISNHWLTAWMGLEINTLAIIPLMTKPHHPRSMESAIKYFMIQATASMIILFSAIFNASTTNQWMTGQISNTSASFMMTIALAMKLGLAPFHFWVPEVTQGIPLLSGMLLLTWQKIAPISIFYQISPSLNMSLLMILSITSTLLGGWGGLNQTQLRKILAYSSIAHMGWMAIIIMIYPSLTILNLILYLASTITMFMVLNQSSSTKINSLSILWNKSAPNMIIITLTLLSLGGLPPLTGFMPKWLILQELINFNNIPLAMMLALSTLLNLFFYMRIIYSSTLTMFPSINNTKMQWTLYSHKTISPIPTLTIISSLLLPMTPVFITLS
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PLPHP_MYCTO
Sequence: MAADLSAYPDRESELTHALAAMRSRLAAAAEAAGRNVGEIELLPITKFFPATDVAILFRLGCRSVGESREQEASAKMAELNRLLAAAELGHSGGVHWHMVGRIQRNKAGSLARWAHTAHSVDSSRLVTALDRAVVAALAEHRRGERLRVYVQVSLDGDGSRGGVDSTTPGAVDRICAQVQESEGLELVGLMGIPPLDWDPDEAFDRLQSEHNRVRAMFPHAIGLSAGMSNDLEVAVKHGSTCVRVGTALLGPRRLRSP
What is the function of this protein?
Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.
What are the official names of this protein?
Pyridoxal phosphate homeostasis protein, PLP homeostasis protein.
What is the protein family that this protein belongs to?
Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
Protein: ZNF74_HUMAN
Sequence: MEIPAPEPEKTALSSQDPALSLKENLEDISGWGLPEARSKESVSFKDVAVDFTQEEWGQLDSPQRALYRDVMLENYQNLLALGPPLHKPDVISHLERGEEPWSMQREVPRGPCPEWELKAVPSQQQGICKEEPAQEPIMERPLGGAQAWGRQAGALQRSQAAPWAPAPAMVWDVPVEEFPLRCPLFAQQRVPEGGPLLDTRKNVQATEGRTKAPARLCAGENASTPSEPEKFPQVRRQRGAGAGEGEFVCGECGKAFRQSSSLTLHRRWHSREKAYKCDECGKAFTWSTNLLEHRRIHTGEKPFFCGECGKAFSCHSSLNVHQRIHTGERPYKCSACEKAFSCSSLLSMHLRVHTGEKPYRCGECGKAFNQRTHLTRHHRIHTGEKPYQCGSCGKAFTCHSSLTVHEKIHSGDKPFKCSDCEKAFNSRSRLTLHQRTHTGEKPFKCADCGKGFSCHAYLLVHRRIHSGEKPFKCNECGKAFSSHAYLIVHRRIHTGEKPFDCSQCWKAFSCHSSLIVHQRIHTGEKPYKCSECGRAFSQNHCLIKHQKIHSGEKSFKCEKCGEMFNWSSHLTEHQRLHSEGKPLAIQFNKHLLSTYYVPGSLLGAGDAGLRDVDPIDALDVAKLLCVVPPRAGRNFSLGSKPRN
What is the function of this protein?
May play a role in RNA metabolism.
What are the official names of this protein?
Zinc finger protein 74, Zinc finger protein 520, hZNF7.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS19_AROAE
Sequence: MARSIKKGPFVDAHLLKKVDAVRTSNDKRPIKTWSRRSTVLPDFVGLTIAVHNGRQHVPVFVSENMVGHKLGEFALTRTFKGHAASKKAKR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: RL30_BUCAP
Sequence: MKTIKITQIKSSIGRIPDHKKTLLGLGLRHIGHSVIRQDTPSIRGMIKKISYILKIQEE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: LDHD_PEDAC
Sequence: MKIIAYGIRDDEKPYLDEWVTKNHIEVKAVPDLLDSSNIDLAKDYDGVVAYQQKPYTADLFDKMHEFGIHAFSLRNVGLDNVPADALKKNDIKISNVPAYSPRAIAELSVTQLLALLRKIPEFEYKMAHGDYRWEPDIGLELNQMTVGVIGTGRIGRAAIDIFKPFGAKVIAYDVFRNPALEKEGMYVDTLEELYQQANVITLHVPALKDNYHMLDEKAFGQMQDGTFILNFARGTLVDTPALLKALDSGKVAGAALDTYENEVGIFDVDHGDQPIDDPVFNDLMSRRNVMITPHAAFYTRPAVKNMVQIALDNNRDLIEKNSSKNEVKFE
What is the function of this protein?
Has both D-lactate and D-glycerate dehydrogenase activities.  Equally active on pyruvate and hydroxypyruvate.
What are the official names of this protein?
D-lactate/D-glycerate dehydrogenase, D-LDH/GDH, D-specific 2-hydroxyacid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
Protein: EIF3I_USTMA
Sequence: MRPILLSGHERSLTQVKFNREGDLLFSVAKDPIINAWFSHNGERLGTYEGHNGTVWTVDVDSTSTLLVSGSADNQMRLWEVATGKCLFTWEFTTAAKRVAFSEDCSQVLVVTEQRMGFRGSLRVFRINRDPATWTQQDVEPTRTITFSGPKAVVAAFAPCDQYIVTGHEDGKVAIYYHDDKEPESGIDAELEENSTKAHTDVISDLQMSADRTYFVTSSRDKTSKLIDSKTLQVIKTYATETPLNSASIHPTKPFVIVGGGQDAMNVTTTSARQGRFETRFWHKVFEEECARLPGHFGPINTIAIHPAGIAYASGGEDGYVRVNWFDPGFFNSKLYGADLELALEDQ
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit I, eIF3i, Eukaryotic translation initiation factor 3 39 kDa subunit homolog, eIF-3 39 kDa subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit I family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_HALMA
Sequence: MSSEYQIGHEGEFSFRGHTLDELQEMELEEVAELLPARQRRSIVRGLTEEKHKLLEKAREAGEEETANDPIRTHLRDMPVVPEMVGLTFAVHDGQNFERVKVEPEMLGHYLGEFQLTRSSVEHGQAGIGATRSSKFVPLK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19, HS18, HmaS19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: PURT_SALTY
Sequence: MTLLGTALRPAATRVMLLGAGELGKEVAIECQRLGIEVIAVDRYPDAPAMHVAHRSHVINMLDGEALRHVITEEKPHYIVPEIEAIATDTLRELEGEGLNVVPCARATQLTMNREGIRRLAAEELGLPTSTYRFADSEASFHDAVAAVGFPCIVKPVMSSSGKGQSFIRSAEQLAQAWEYAQQGGRAGAGRVIVEGVVKFDFEITLLTVSAVDGVHFCAPVGHRQQDGDYRESWQPQQMSELALKRAQEIARHVVLALGGHGLFGVELFVCGDEVIFSEVSPRPHDTGMVTLISQDLSEFALHVRAFLGMPVGAIRQYGPAASAVILPQLTSQNVTFDNVHAAVGAGVQVRLFGKPEIDGTRRLGVALATGENVEEAVIRAKKAVSRVTVKG
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: Y520_HAEIN
Sequence: MTALSEIFVPLHRIIPFSNVEGQGNRSSIFLQGCKLNCLYCHNPETIPRYTESAKLVSLQYLYEQVMEAVPFIRGVTVSGGEPTIHHKKLVPLFKALRSQGLTCYLDSSGFFEFDRVCSLIDVTDKFLFDLKGEGIGLQTLCFDRKNQAGIVPQQVIPERLHIKNDKLERNLQNLAALLPLNKVEEVRLVFLKHFFDAEHLVGKVAQLLRNYPDVALKIIRVHSKGVRDEAGLSAYIPSVEETNALSAYARQCGINKILTIL
What are the official names of this protein?
Putative glycyl-radical enzyme activating enzyme HI_0520, GRE activating enzyme HI_0520.
What is the protein family that this protein belongs to?
Belongs to the organic radical-activating enzymes family.
Protein: RLMG_ECOSM
Sequence: MSHLDNGFRSLTLQRFPATDDVNPLQAWEAADEYLLQQLDDTEIRGPVLILNDAFGALSCALAEHKPYSIGDSYISELATRENLRLNGIDESSVKFLDSTADYPQQPGVVLIKVPKTLALLEQQLRALRKVVTPDTRIIAGAKARDIHTSTLELFEKVLGPTTTTLAWKKARLINCTFNEPPLVDAPQTVSWKLEGTDWTIHNHANVFSRTGLDIGARFFMQHLPENLEGEIVDLGCGNGVIGLTLLDKNPQAKVVFVDESPMAVASSRLNVETNMPEALDRCEFMINNALSGVEPFRFNAVLCNPPFHQQHALTDNVAWEMFHHARRCLKINGELYIVANRHLDYFHKLKKIFGNCTTIATNNKFVVLKAVKLGRRR
What is the function of this protein?
Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase G, 23S rRNA m2G1835 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RlmG.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPNP_PELPD
Sequence: MSEFSNVTVIKKANIYFEGKVASHTVLFPDGTKKTLGIMQAGDYEFSTANAEVMEILSGTLEWQMKGECCWKTIGAGESFQIPADSVFLMKVPAVADYCCSYIQ
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: PSTB2_LACPL
Sequence: MSTILTTENLSLFYGKKEALKGINIDFDDKGITALIGPSGCGKSTFLRCLNRMNDLIPNVTITGEVNFNGHNIYAPTTDTVQLRKEIGMVFQQPNPFPFSIYENVIYGLRLAGVHDKERLDAAVEKSLKQAAIWDEVKDRLHANALSLSGGQQQRVCIARVLAVEPDIILLDEATSALDPISSRMIEETLLNLRQDYTIITVTHNMQQASRISDRTAFFLNGELIEVNDTKQIFMNPVKQETNDYISGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB 2, ABC phosphate transporter 2, Phosphate-transporting ATPase 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SDHD_SALG2
Sequence: MENIQKLIARYPLVEDLVALKETTWFNPGATSLAQGLPYVGLTEQDVNAAHDRLARFAPYLAKAFPQTAAAGGMIESDVVAIPAMQKRLEKEYGQTIDGEMLLKKDSHLAISGSIKARGGIYEVLTHAEKLALEAGLLTTDDDYSVLLSPEFKQFFSQYSIAVGSTGNLGLSIGIMSACIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEDDYGVAVEQGRKAAQSDPNCFFIDDENSRTLFLGYAVAGQRLKAQFAQQGRVVDASHPLFVYLPCGVGGGPGGVAFGLKLAFGDNVHCFFAEPTHSPCMLLGVYTGLHDAISVQDIGIDNLTAADGLAVGRASGFVGRAMERLLDGLYTLDDQTMYDMLGWLAQEEGIRLEPSALAGMAGPQRICAAAAYQQRHGFSQTQLGNATHLVWATGGGMVPEDEMEQYLAKGR
What are the official names of this protein?
D-serine dehydratase, D-serine deaminase, DSD.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family. DsdA subfamily.
Protein: PYRE_KLEP3
Sequence: MKPYQRQFIEFALSKQVLKFGEFTLKSGRKSPYFFNAGLFNTGRDLALLGRFYAEALVDSGIEFDLLFGPAYKGIPIATTTAVALAEHHDRDLPYCFNRKEAKTHGEGGNLVGSPLQGRVMLVDDVITAGTAIRESMEIIQAQGAQLAGVLISLDRQERGRGEISAIQEVERDYGCQVISIITLKELIAYLEEKPEMAEYLASVRAYREAYGI
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.