PharMolix/UniProtQA huggingface dataset:
Protein: MERP_ENTCL
Sequence: MKKLFAALALAAVVAPVWAATQTVTLSVPGMTCASCPITVKHALSKVEGVSKTDVSFDKRQAVVTFDDAKTNVQKLTKATEDAGYPSSLKR
What is the function of this protein?
Involved in mercury resistance.  Acts as a mercury scavenger that specifically binds to a mercuric ion in the periplasm and probably passes it to the cytoplasmic mercuric reductase MerA via the mercuric transport protein MerT.
What are the official names of this protein?
Mercuric transport protein periplasmic component, Mercury scavenger protein, Periplasmic mercury ion-binding protein.
What is the protein family that this protein belongs to?
Belongs to the MerP family.
What are the subcellular locations of this protein?
Periplasm.
Protein: CSGA_SALTY
Sequence: MKLLKVAAFAAIVVSGSALAGVVPQWGGGGNHNGGGNSSGPDSTLSIYQYGSANAALALQSDARKSETTITQSGYGNGADVGQGADNSTIELTQNGFRNNATIDQWNAKNSDITVGQYGGNNAALVNQTASDSSVMVRQVGFGNNATANQY
What is the function of this protein?
Curlin is the structural subunit of the curli.  Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius.  Curli can bind to fibronectin.
What are the official names of this protein?
Major curlin subunit, Fimbrin SEF17.
What is the protein family that this protein belongs to?
Belongs to the CsgA/CsgB family.
What are the subcellular locations of this protein?
Fimbrium. Note=Part of the curli surface structure.
Protein: PER1_ORYSJ
Sequence: MASSRVILALLLAAAAVMASSAQLDEKFYSNSCPSVEAVVRKEMVRALGAAPSLAGPLLRMHFHDCFVRGCDGSVLLDSAGNSTAEKDATPNQTLRGFGFVERVKAAVEKACPGTVSCADVLALMARDAVWLSKGPFWAVPLGRRDGRVSIANETDQLPPPTANFTELTQMFAAKNLDLKDLVVLSAGHTIGTSHCFSFTDRLYNFTGLDNAHDIDPTLELQYMARLRSKCTSLQDNTTLVEMDPGSFKTFDLGYFKNVAKRRGLFHSDGELLTNGFTRAYVQRHAGGGYKDEFFADFAASMVKMGGVEVLTGSQGEIRKKCNVVN
What is the function of this protein?
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.  These functions might be dependent on each isozyme/isoform in each plant tissue.
What are the official names of this protein?
Peroxidase 1.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LPXD_VIBVU
Sequence: MMTLTLAELAKITGGELHGDETVCVSRVAPMDKAGEGDVTFLSNPKYAVHLAECKATVVMLKAEQRKHCSGHVLVVDDPYVAFAKVAQALDTTPKPADGIAPSAVIASDAILGQNVSIGANAVIETGVTLGDNVVIGAGCFIGKNAAIGQNTKLWANVTIYHQVQIGADCLIQAGTVIGSDGFGYANDRGEWIKIPQLGSVRIGNRVEIGACTTIDRGALDDTIIEDNVVLDNQLQIAHNVHIGYGTVMPGGTVVAGSTTIGKYCAIGGASVINGHITIADGVNITGMGMVMRSIEEKGVYSSGIPLQTNKEWRKTAARVHRIEEMNKRLKAIEKIVEQKKED
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: VSP1_PROEL
Sequence: VIGGDECNINEHPFLVLVYYDDYQCGGTLINEEWVLTAAHCNGKNMEIYLGVHSKKVPNKDVQRRVPKEKFFCDSSKTYTKWNKDIMLIRLDRPVRKSAHIAPLSLPSSPPSVGSVCRVMGWGTITSPQETYPDVPHCAKINLLDYSECRAAYPGLPPKSRTLCAGVLEGGKDTCGGDSGGPLICNGQFQGIVSWGGDPCAQPHEPGSYTNVFDHLDWIKGIIAGNTDATCPL
What is the function of this protein?
Thrombin-like snake venom serine protease that clots rabbit fibrinogen.  Only the beta chain of fibrinogen (FGB) is cleaved, releasing fibrinopeptide B.  Incubation with human fibrinogen alpha and beta resulted in cleavage of both fibrinogen chains but generated neither fibrinopeptide A nor fibrinopeptide B.  Promotes clotting of rabbit fibrinogen, but not bovine or human fibrinogen.
What are the official names of this protein?
Thrombin-like enzyme elegaxobin-1, SVTLE, Elegaxobin I, Fibrinogen-clotting enzyme, Snake venom serine protease, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YUGK_BACSU
Sequence: MENFTYYNPTKLIFGKGQLEQLRKEFKRYGKNVLLVYGGGSIKRNGLYDQVTGILKEEGAVVHELSGVEPNPRLATVEKGIGLCREHDIDFLLAVGGGSVIDCTKAIAAGVKYDGDAWDIFSKKVTAEDALPFGTVLTLAATGSEMNPDSVITNWETNEKFVWGSNVTHPRFSILDPENTFTVPENQTVYGMVDMMSHVFEQYFHNVENTPLQDRMCFAVLQTVIETAPKLLEDLENYELRETILYAGTIALNGTLQMGYFGDWASHTMEHAVSAVYDIPHAGGLAILFPNWMRYTLDTNVGRFKNLMLNMFDIDTEGKTDKEIALEGIDKLSAFWTSLGAPSRLADYNIGEEKLELIADIAAKEMEHGGFGNFQKLNKDDVLAILRASL
What are the official names of this protein?
Probable NADH-dependent butanol dehydrogenase 2.
What is the protein family that this protein belongs to?
Belongs to the iron-containing alcohol dehydrogenase family.
Protein: HSCB_BURPS
Sequence: MVSLKDSHFDLFHLPARFALDEPTLDAAYRAVQSQVHPDRFAAAGDAQKRIAMQWATRANEAYQTLRDPLKRATYLLHLRGVDVGAENNTAMEPAFLMQQMEWRERIEDAAGAKNVDALDALLAELRDERRARLAKLGALLDSGSDQGAAEAVRQLMFVERVSAEIGAQIERLEH
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB homolog.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: BIOH_AERHH
Sequence: MSVSVERFGQGPDLVLLHGWGMNGAVWHGIVPALASRYRVHLVDLPGFGNSPLAGEVEYSLPWLAEEVAAILPEQCHLLGWSLGGLVASQLALSHPERLHSLITVASSPCFMARDEWPGIAPKVLAGFNQMLAGDFKQTIERFLAIQAMGSEHARDDIRQLRHWLAERPAPQLAALEAGLGLLAEVDLRDELTPLSLPWLRVYGRLDSLVPKASIPLLDERYPSSRSVVLEKASHAPFISHPQQFIEIIEHFVG
What is the function of this protein?
The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete.  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.
What are the official names of this protein?
Pimeloyl-[acyl-carrier protein] methyl ester esterase, Biotin synthesis protein BioH, Carboxylesterase BioH.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MED21_CAEEL
Sequence: MADRMTQLQDMINEMAGLMTNAIGVLQATAPPCEFGAISQELEDEPNCAIFAAGIAKAAKNIEILIDSFPIEAGNQEAEVEEKMIKNDEKQREKVNELVGLVGDSNRLVGVVQKKLAEISKTQMSSRPSE
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 21, CeSRB7, Mediator complex subunit 21.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 21 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYNS_MAIZE
Sequence: MEASGEKAAVVRRLMEAKEVSGKTFSGIAAETGLTNVYVAQLLRRQAQLKADTVPALRAALPTLTDDLIELMMQPPFRSYHPNIVHEPAIYRLNEAVMHFGESIKEIINEEFGDGIMSAIDFYCSVDKVEGADGKDRVVVTFDGKYLPYTEQKSEHMMSRPTRKTS
What is the function of this protein?
Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
What are the official names of this protein?
Cyanate hydratase, Cyanase, Cyanate hydrolase, Cyanate lyase.
What is the protein family that this protein belongs to?
Belongs to the cyanase family.
Protein: KGUA_EHRRG
Sequence: MNNNLKSRGIMLVMSSPSGGGKTTISQLLVNELQGEIIRSVSVTTREPRNEEVEGKDYFFVTEDEFHHLCNTNQMLEYAKVFGNYYGIPRRFVMDNINNGISILFSIDWQGAFKLIDIMSEHVVSVFILPPSMEELKRRLYNRSGESDMINQRLKEAAFEISHCYRYNYIIVNHNIEESVQQIKSIFIAEKLKTHRKMFLEQVVKSYYI
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCD47_MACFA
Sequence: MKAFHTFCVVLLVFGSVSEAKFDDFEDEEDIVEYDDNDFAEFEDVMEDSVTESPQRVITTEDDEDETTVELEGQDENQEGDFEDADTQEGDTESEPYDDEEFEGYEDKPDTSSSKNKDPITIVDVPAHLQNSWESYYLEILMVTGLLAYIMNYIIGKNKNSRLAQAWFNTHRELLESNFTLVGDDGTNKEATSTGKLNQENEHIYNLWCSGRVCCEGMLIQLRFLKRQDLLNVLARMMRPVSDQVQIKVTMNDEDMDTYVFAVGTRKALVRLQKEMQDLSEFCSDKPKSGAKYGLPDSLAILSEMGEVTDGMMDTKMVHFLTHYADKIESVHFSDQSSGPKIMQEEGQPLKLPDTKRTLLFTFNVPGSGNTYPKDMEALLPLMNMVIYSIDKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAALRREQKKLEKKQMKMKQIKVKAM
What is the function of this protein?
Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes.  The MPT complex takes over after the SEC61 complex: following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex, the MPT complex occludes the lateral gate of the SEC61 complex to promote insertion of subsequent transmembrane regions (By similarity).  Within the MPT complex, the PAT subcomplex sequesters any highly polar regions in the transmembrane domains away from the non-polar membrane environment until they can be buried in the interior of the fully assembled protein.  Within the PAT subcomplex, CCDC47 occludes the lateral gate of the SEC61 complex (By similarity).  Involved in the regulation of calcium ion homeostasis in the ER.  Required for proper protein degradation via the ERAD (ER-associated degradation) pathway (By similarity).  Has an essential role in the maintenance of ER organization during embryogenesis (By similarity).
What are the official names of this protein?
PAT complex subunit CCDC47, Coiled-coil domain-containing protein 47.
What is the protein family that this protein belongs to?
Belongs to the CCDC47 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Rough endoplasmic reticulum membrane.
Protein: EIF3H_ASPFU
Sequence: MAENETPLTAVKVEALVVMKIMKHCSQTFPTTATGSIVGMDVGGTLEITNSFPFPVVEVPPESHFDNAAANPAAAAPRAKANTVYQAEMIRMLREVNVDANNVGWYTSANMGNFVNMNVIENQFFYQKEMNERTVALVHDVSRSSQGSLSLRAFRLSPKFMTAFKENKFTSEELQKSGLRYQDIFVELPVEIHNSHLITSFIHQLQTPNIPAPTELPSSLAALESGPFVKSSILAPNFDNLALSIDPFLEKNCDLLLDSIETHHTETNNFQYYQRSLAREQQRISAWQQKRKQENATRAALKQPLLPEDEWQRLFKLPQEPSRLESMLNSRQVDQYARQIDSFVSSTTGKMFAVKGNLLPGETAK
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit H, eIF3h.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_MYCGA
Sequence: MAVQQRRSSKHRRDKRRSHDALAVNLINVCKHCGKFKRAHRACSCGMYNELRITKAK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: CRCB_PARDP
Sequence: MKHTFLQVALGGALGSAARYGVNILAGRLTPGFPLGTLSVNIAGCLAMGLLAALLAHRGGQHLAPFLLTGMLGGFTTFSAFALDTMTLWERGEIATALGYVLGSVVLSLAAVIAGLTVGRGLFA
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KISSR_MOUSE
Sequence: MATEATLAPNVTWWAPSNASGCPGCGVNASDDPGSAPRPLDAWLVPLFFATLMLLGLVGNSLVIYVICRHKHMQTVTNFYIANLAATDVTFLLCCVPFTALLYPLPAWVLGDFMCKFVNYIQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALAVSLSIWVGSAAVSAPVLALHRLSPGPRTYCSEAFPSRALERAFALYNLLALYLLPLLATCACYGAMLRHLGRAAVRPAPTDGALQGQLLAQRAGAVRTKVSRLVAAVVLLFAACWGPIQLFLVLQALGPSGAWHPRSYAAYAVKIWAHCMSYSNSALNPLLYAFLGSHFRQAFCRVCPCCRQRQRRPHTSAHSDRAATHTVPHSRAAHPVRIRSPEPGNPVVRSPCAQSERTASL
What is the function of this protein?
Receptor for metastin (kisspeptin-52 or kp-52), a C-terminally amidated peptide of KiSS1.  KiSS1 is a metastasis suppressor protein.  Activation of the receptor inhibits cell proliferation and cell migration, key characteristics of tumor metastasis.  The receptor is essential for normal gonadotropin-released hormone physiology and for puberty.  The hypothalamic KiSS1/KISS1R system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood.  Analysis of the transduction pathways activated by the receptor identifies coupling to phospholipase C and intracellular calcium release through pertussis toxin-insensitive G(q) proteins.
What are the official names of this protein?
KiSS-1 receptor, KiSS-1R, G-protein coupled receptor 54, G-protein coupled receptor OT7T175, mOT7T175, Kisspeptins receptor, Metastin receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PESC_PYRTR
Sequence: MHILTPTQAPLVPNPPHELMYTSSPLQISLPDFRRLCIFKGIYPPREPRNKKKVSKGSTAATTFYYTKDIQYLLHEPLLAKFREHKAVAKKIGRALGRGESGDASRLEKNLMPKVKLDHIIKERYPTFVDALRDLDDALSMLFLFANLPSSDHIPAKTIALCQRLTREFEHYVITSHSLRKSFLSIKGIYYQATIQGQDILWLVPYRFVQRTGGDIDFRIMGTFVEFYTTLLGFVNYRLYTSIGLVYPPKFNARSDEQGGELAAFQLEGKATATNGASNGHAEDAEINPEAQAIADRIGAMPDVEEEEATTAVAKTGAEDDEEEANEEIDKFEPTAPDADILPQPQASSAEVASLFAPFTFYLSRETPRGSLEFILKAFGCKRVGWDGVLGDGAFTTNESDPAITHQIVDRPALSNGAPASNVQETENGGAAAPKAQWPYSMMPGRTYVQPQWVWDSINQGKLLRADHYSPGADLPPHLSPWVKPKKGEYDPNLPLAAQQPEGEAEAFEDEGDEETAFDVDGDEDMEAIVDREGSVEVGEGMDVADDSEDDSDDDESDEEDGPAGDEDDLDSDAESDISEGEAARLQHQRELEAEATGKKLEVKKPTRKEENATIRKKAEKKKRAEEEERERQKMMLSNKKRKLLKRIEYGENKRDNESENLRRKRARVEKAKAAAEAV
What is the function of this protein?
Component of the NOP7 complex, which is required for maturation of the 25S and 5. 8S ribosomal RNAs and formation of the 60S ribosome.
What are the official names of this protein?
Pescadillo homolog, Nucleolar protein 7 homolog.
What is the protein family that this protein belongs to?
Belongs to the pescadillo family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: FABZ_STRP1
Sequence: MDIREIQAALPHRYPMLLVDRVLEVSDDHIVAIKNVTINEPFFNGHFPHYPVMPGVLIMEALAQTAGVLELSKEENKGKLVFYAGMDKVKFKKQVVPGDQLVMTATFIKRRGTIAVVEARAEVDGKLAASGTLTFACGQ
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y494_LACLS
Sequence: MDLEKLKEETQIIIDDVLKQTEIKSGQVFVLGLSSSEVNGGLIGHASSAEIGQVIVSVIHKTLSDKGIYLAVQACEHLNRALLIEEELADKKDWEIVSVVPQLHAGGSGQVAAYQLFKSPVEVEHIVAQAGLDIGDTSIGMHVKHVQIPVRPISKELGGAHVTSLKSRPKLIGGERARYE
What are the official names of this protein?
UPF0340 protein LACR_0494.
What is the protein family that this protein belongs to?
Belongs to the UPF0340 family.
Protein: Y964_STAA1
Sequence: MLHLHILSWVLAIILFIATYLNISKNQGGSPFFKPLHMILRLFMLLTLISGFWILIQSFMNGGANHMLLTLKMLCGVAVVGLMEVSIAKRKRHEQSHKMFWITMALIIITMVLGVILPLGPISKLFGIG
What are the official names of this protein?
UPF0344 protein SAHV_0964.
What is the protein family that this protein belongs to?
Belongs to the UPF0344 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL1_STAMF
Sequence: MPLPSKEELKEAIVKAVQYSPKRNFKQSVELIVVLKDVDPRSPEGRIRETIFLPKGLGKDKIICVVADGEMAEKARAGGAHRVITRDELLALSKKDAKKVAQECDWVLVRTDLMANAGRILGPALGPRGKIPVPVPPAADIVSVMNRYKSAILLRNKDQPQLMTRIGTEDMNPEDLVINAQTILSRLETKLPNGAHNIAKIVVKTTMGPPIEVMG
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: TRUB_STRMU
Sequence: MISGIINLKKEAGMTSHDAVFKLRKILKEKKIGHGGTLDPDVIGVLPIAVGKATRVLEYMTEAGKVYEGQITLGFSTTTEDASGELLQWTPVDETLSVELIDQAMTCFMGQITQVPPMYSAVKVNGKKLYEYARAGQEVERPQRQVRIYDFKRTSDLVFEDECCHFDFRVSCSKGTYIRTLAVDLGQKLGYASHMSFLKRTASAGLDLSQALTLAEIAEKVEEKDFSFLLPIEYGVLDLPRIDLNPKQTKEVSFGRRLKLLRQEELLAAFFENQLVAVLEKRDTSYKPKKVFL
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: Y383B_ATV
Sequence: MARREKNPIRATVAMNIGLSDSLLAFVNNYVKALRFSLFWMKENVKNPNEKGALSKVHEGLYEKLRKEYNLPSKVTEDCYRDALAIYKSWYNNPKKGRFPRVYKPTVWLTPKQSYTVDLEKMTVRIASVGELPILGYPRNLKEYANWKMKEARLTIKDGKALLKVTFEKEEEKVKPKDSVAVDINMNDIVVGKDDTHYVRIPTRLHDAHHFKSLAENLQKKYPRRWKQNRRILHRARSFHQKAKLIMEDYARKVGKWVVEIAEGLGANVIKLEDLKNLIKDVNKLPAEFRDKLYLMQYRRIQYWIEWQAKKHGMIVEFVNPSYSSVSCPKCGHKMVEIAYRYFHCPSCGYENDRDVIAIMNLNGRGSLTLSTAPQMRDVAPNR
What are the official names of this protein?
TnpB-like protein ORF383B.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transposase 35 family.
Protein: NANP_MOUSE
Sequence: MGLSRVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYSTCITDVRTSHWEEAIQETKGGADNRKLAEECYFLWKSTRLQHMILADDVKAMLTELRKEVRLLLLTNGDRQTQREKIEACACQSYFDAIVIGGEQKEEKPAPSIFYHCCDLLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWINKSGRVPLTSSPMPHYMVSSVLELPALLQSIDCKVSMSV
What are the official names of this protein?
N-acylneuraminate-9-phosphatase, Haloacid dehalogenase-like hydrolase domain-containing protein 4, Neu5Ac-9-Pase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. NANP family.
Protein: LPXH_ECO27
Sequence: MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHHQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQTLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVNAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NU2C2_PANGI
Sequence: MIWHVQNENFILDSTRIFMKAFHLLLFDGSLIFPECILIFGLILLLMIDSTSDQKDIPWLYFISSTSLVMSITALLFRWREEPMISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDLITIFVAPECFSLCSYLLSGYTKKDVRSNEATMKYLLMGGASSSILVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGIGFKLSPAPSHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNDGYASMITYMLFYISMNLGTFACIVLFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGLPPLAGFFGKLYLFWCGWQAGLYFLVLIGLLTSVVSIYYYLKIIKLLMIGRNQEITPHVRNYRRSPFRSNNSIELSMIVCVIASTIPGISMNPIIAIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 B, chloroplastic, NAD(P)H dehydrogenase, subunit 2 B, NADH-plastoquinone oxidoreductase subunit 2 B.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: COX8_NEUCR
Sequence: MFSRVALRAAPRQQPFSLVARRTFQTTRAQLSSPYHYPEGPRSNLPFNPKTRFFWFRYLMYCVVGFGSPVAIAVWQTYRPRS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of Cox2 and heme A of Cox1 to the active site in Cox1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 8, mitochondrial, Cytochrome c oxidase polypeptide VIIc, Cytochrome c oxidase subunit Cox8.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase VIIc family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: ILVC_AKKM8
Sequence: MDIIHDNAADLSALNGKTVAVIGYGAQGRAQALCMRDSGVNVIIGVRPGKSFDAAAQDGFQVMSVAEAAEKADIIHILLPDESHGAVYEAEIKPHLKAGKTLCCSHGFAYVFNTIVPPADVDVIMVAPKGPGTEVRRVFEEGFGCPGLIAVHQNPSGKARDVALAMAKAEGLTRGGVLECTMAQETYEDLFGEQNVLCGGLVDLMKYGFETLTEAGYPPEMAYFECVHEAKLIVDLIYNGGIQKMNSVISNTAEFGEYYNGPQILPAEVKERMKESLKRIESGKFAKDWLEEAAKGAPNLKAKREALGQHPVEIVGAKIRSLFERN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.