PharMolix/UniProtQA huggingface dataset:
Protein: URE3_BURCM
Sequence: MKLTPREKDKLLIFTAALLAERRRARGLKLNYPEAVAFITAALMEAARDGKTVAEVMHYGTTLLTRDDVMDGVPEMIPDIQVEATFPDGTKLVTVHHPIP
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSDA_ARATH
Sequence: MEEAKVEAKDGTISVASAFSGHQQAVHDSDHKFLTQAVEEAYKGVDCGDGGPFGAVIVHNNEVVASCHNMVLKYTDPTAHAEVTAIREACKKLNKIELSECEIYASCEPCPMCFGAIHLSRLKRLVYGAKAEAAIAIGFDDFIADALRGTGVYQKSSLEIKKADGNGAAIAEQVFQNTKEKFRLY
What is the function of this protein?
Catalyzes the hydrolytic deamination of guanosine, producing xanthosine and ammonia.  Deaminates exclusively guanosine and 2'-deoxyguanosine but no other aminated purines, pyrimidines, or pterines.  Deamination of guanosine by GSDA is the only source of xanthosine production in Arabidopsis.
What are the official names of this protein?
Guanosine deaminase, tRNA-specific adenosine deaminase TAD4, AtTAD4.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes predominantly to the nucleus.
Protein: DUT_PARXL
Sequence: MKLDLKILDARMRDQLPAYATTGSAGLDLRACLDEPLTLKPGETALVPTGLAIHVGDPGYAALILPRSGLGHKHGIVLGNLVGLIDSDYQGQLMISTWNRGETTFVLNPMERLAQLVIVPVVQAEFNIVDDFETSERGAGGFGSTGKH
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: ODPB_RICPR
Sequence: MQITVREALRDAMQEEMLRDEKVFVIGEEVAEYQGAYKVTQGLLEQFGSKRVIDTPITEYGFAGLAVGAAFAGLRPIVEFMTFNFAMQAFDHIVNSAAKTHYMSGGQVKCPIVFRGPNGAASRVAAQHSQNYTACYSHIPGLKVVAPYSAEDHKGLMLTAIRDDNPVIFLENEILYGHSFDVPDIIEPIPFSKAKILKEGSNVTIVTFSIQVKLALDVVNILQNDNIDCELIDLRTIKPLDTDSIIESVKKTNRLVIVEEGWFFAGVGASIASIVMKEAFDYLDAPIEIVSGKDVPLPYAVNLEKLAMPSANDLIEAVKKVCYYSI
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
What are the official names of this protein?
Pyruvate dehydrogenase E1 component subunit beta.
Protein: PURA_GLOVI
Sequence: MANVIVVGAQWGDEGKGKITDLLSVSADVVVRYQGGINAGHTVCVGEQTFKLHLIPSGILYPETCCVIASGTVVDPKVLLEEIRHLEELGISTKNLFIAETAHVTMPYHRLIDIAEEERRGKNRIGTTGRGIGPTYADKSGRTGFRVLDLMQPEGFREKLEWIVPLKNVLLERLYNLPPLAVDQVAEQYLAYAEQLRPYVIDASLLIDQAVRTHRNILFEGAQGTLLDLDHGTYPYVTSSNPVAGGACVGAGVGPTIIDRVIGVAKAYTTRVGEGPFPTELRDEVGRHLGERGAEFGTTTGRPRRCGWFDAVIGRYAVRINGLDCLAITKLDVLDELESIKVCVAYHCPSKTVEEFPSDANLFGRCEPVYETLPGWKEPTGHCRTLEELPPKARDYLEFLAHQMKTPIALVSVGANREQTIIVEDPIHGPKRGLLGHNGD
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUCA_BACSU
Sequence: MTTDIIKTILLVIVIIAAAAVGLIKGDFFSADQKTSQTKEYDETMAFPSDRYPETAKHIKDAINEGHSEVCTIDRDGAEERREQSLKDVPSKKGYDRDEWPMAMCKEGGEGASVEYISPADNRGAGSWVGHRLTDYPDGTKVLFTIQ
What is the function of this protein?
By degrading DNA that enters the cell, plays a role in the competence of cells to be transformed.  Degrades both double-stranded, linear and covalently closed circular DNA.
What are the official names of this protein?
DNA-entry nuclease, Competence-specific nuclease.
What is the protein family that this protein belongs to?
To B.subtilis NucB.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: HLY1C_STACC
Sequence: MSGIVEAISNAVKSGLDHDWVNMGTSIADVVAKGADFIAGFFS
What is the function of this protein?
Virulence factor.  Causes hemolysis of erythrocytes from sheep (HD(50)=7. 53 mM), rabbit (HD(50)=28. 07 mM), guinea pig (HD(50)=4. 23 mM), dog (HD(50)=4. 37 mM) and human (HD(50)=3. 32 mM).  Acts synergistically with beta-hemolysins from S. aureus ATCC 25923.  Cytotoxic towards human dermal fibroblasts.
What are the official names of this protein?
Hemolysin H1C.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal hemolytic protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y129_METI4
Sequence: MKIHYYGHSCFGLEIGSSFLLFDPFISQNPLSDPTLLDTLNPQYILISHGHFDHIADASPIAKRTQAPILSNFEITLWLEKQGLSQVLPMNLGGNRSFDFGKIHYVQAAHSSSLPDGSYGGTAGGFIVEGPEGILYYAGDTALMSDMKLFGECFQIDIALLPIGGTFTMGVDEAIRAAHLLNCKQVMGVHFDTFEAIKIDHEEAKKKFQDEEIPFRLLKVKESLIL
What are the official names of this protein?
UPF0173 metal-dependent hydrolase Minf_0129.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: TRPA_CHLPM
Sequence: MTENRITALLRQDKKLLLAYYMPEFPVAGATLPVLEALQESGADIIELGIPFSDPVGDGPVIQEAAHRSIANGVSLHRLLDIVGRARRGEGCRKITVPILLMGYCNPLIAYGGDCFLTDATEAGIDGLLLPDLPPEEAGEFLERAKAFSMTVVFLISPVTPPERIEMIDGMSTDFSYCLAVNATTGTAKLSEGDTEASVDEYLKRVRRHTKKKFVVGFGIKDRERVEHMWRFADGAVVGTALLQNIASAGTPQEAARLAGEFWRTLR
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: LPXK_AZOSB
Sequence: MAAARGAMPTAPSYWRSRGPRALLLYPLSLLFGLLAALRRRLYRAGLLSQVRLPVKVIVVGNIAVGGSGKTPVVAWLVEQLRAAGWHPGIISRGHGGSARGVLEVVASGDAGVCGDEPLLLARLTGVPVFVGRDRPAAAAALLQAHPECDVIVSDDGMQHYRLARDLELAVVDPATLGNRWLLPAGPLREPVGRLDRVDLVIRHGDEGELPPRLGARAVPMRLVGDGFRGVADPARRCEASAFRGRRVHAVAGIGRPQRFFDQLAAMGLDVVPHPFPDHHRFVAADLDFAPGEPKLMTSKDAVKCAPFAPADAWEFPVTAEIGSGAAERILERLQHGRPPA
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: PDXH_ECODH
Sequence: MSDNDELQQIAHLRREYTKGGLRRRDLPADPLTLFERWLSQACEAKLADPTAMVVATVDEHGQPYQRIVLLKHYDEKGMVFYTNLGSRKAHQIENNPRVSLLFPWHTLERQVMVIGKAERLSTLEVMKYFHSRPRDSQIGAWVSKQSSRISARGILESKFLELKQKFQQGEVPLPSFWGGFRVSLEQIEFWQGGEHRLHDRFLYQRENDAWKIDRLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: RNT_SHESR
Sequence: MSDISDANKLKHRFRGYFPVVIDVETAGFNSQTDALLEIAVTLLKMDDEGLLGIDKTLHFNIEPFEGANLEPEALAFNGIDPTNPLRGAVSEKEAFLEIFKAVKKAQKASDCHRSIIVAHNAAFDHGFVSKAIERCDLKRSPFHPFATFDTATLAGLAIGHTVLAKACIMAGIPFDNKEAHSALYDTERTAELFCYIVNRWKHLGGWPLLAAGESEDTDGEE
What is the function of this protein?
Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang.  Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A).  Also appears to be involved in tRNA biosynthesis.
What are the official names of this protein?
Ribonuclease T, Exoribonuclease T, RNase T.
What is the protein family that this protein belongs to?
Belongs to the RNase T family.
Protein: RLA4_SCHPO
Sequence: MKYLAAYLLLTVGGKQSPSASDIESVLSTVGIEAEAERVESLISELNGKNIEELIAAGNEKLSTVPSAGAVATPAAGGAAGAEATSAAEEAKEEEAAEESDEDMGFGLFD
What is the function of this protein?
Plays an important role in the elongation step of protein synthesis.
What are the official names of this protein?
60S acidic ribosomal protein P2-beta, A4.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein P1/P2 family.
Protein: RK21_EMIHU
Sequence: MSSYAIVEACGKQMWIEEGKFYDFDKLPFSKGDVFSLSDILLVKMDDSAEIGQPYLTDKYSVELRVLQHFSGPKIRVYKMRSKKKTRKTFGHRSKLTRVLVQSISKKGVAQTTCFM
What is the function of this protein?
This protein binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L21, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SYS_GLUOX
Sequence: MHDLKALRADPAAFDAALARRGLSPVGQQLVSDDEGRRAALAALQEAQGARKALAKEIGLLKRQKLDTAEIEAKAVALRDQIAGLEERANTIQTRIDDVLKSLPNCLDASVPDGKGEDENVVVHVRGEKREFAFEAKQHFELGEALGLMDFPTAAKLSGTRFVVLRGALARLERALGQFMLDTHTTEFGYSETSVPLLVNDDAMYGTDKLPKFAEDSFRTEDGRWLIPTAEVPLTASVMGEILPADALPIRMTALSQCFRSEAGSAGRDVRGMLRQHQFTKCELVSVVKPEDSDAEHERMTQAAETVLERLGITFRRMLLCAGDTGFGAAKTFDLEAWLPGQKAWREISSCSNTRDFQARRMNARYRAENGPAFVNTLNGSGLAVGRTMIAVMETYQNEDGSIDIPEVLRPYMGGLNRIG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCAP_I87A0
Sequence: MASQGTKRSYEQMETDGERQNATEIRASVGKMIDGIGRFYIQMCTELKLSDYEGRLIQNSLTVERMVLSAFDERRNRYLEEHPSAGKDPKKTGGPIYKRVGGRWMRELVLYDKEEIRRIWRQANNGDDATRGLTHMMIWHSNLNDTTYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGIGTMVMELIRMIKRGINDRNFWRGENGRKTRSAYERMCNILKGKFQTAAQRAMMDQVRESRNPGNAEIEDLIFSARSALILRGSVAHKSCLPACVYGPAVSSGYDFEKEGYSLVGIDPFKLLQNSQVYSLIRPNENPAHKSQLVWMACHSAAFEDLRLLSFIRGTKVSPRGKLSTRGVQIASNENMDTMESSTLELRSRYWAIRTRSGGNTNQQRASAGQISVQPTFSVQRNLPFEKSTVMAAFTGNTEGRTSDMRAEIIRMMEGAKPEEVSFRGRGVFELSDEKATNPIVPSFDMSNEGSYFFGDNAEEYDN
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: LUM_RABIT
Sequence: LQWLILDHNLLENSKIKGKVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLGSFDGLLNLTFVHLQHNQLKEDAVSAAFKGLKSLEYLDLSFNQMSKLPSGLPASLLTLYLDNNKISDIPDEYFKRFNGLQYLRLSHNELADSGIPGNSFNISSLVELDLSYNKLKNIPTVNENLENYYLEV
What are the official names of this protein?
Lumican, Keratan sulfate proteoglycan lumican, KSPG lumican.
What is the protein family that this protein belongs to?
Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: NNRE_ANODA
Sequence: MKYLNQQEAISIDEELFNEYKFSVDQLMELAGLSCAHVIADAYAPESNKILICCGPGNNGGDGLVAARHLALMNYNPYVYYPKRTEKELFRNLQHQAESMGITVTTDCPDGASVEQEFGLIVDALFGFSFKPPVRDSFLPIMNVLQRSKLPIVSIDIPSGWNVEEGPQNECDIQPACLISLTAPKLCAKRLLNAQHYLGGRFVPKRLEEKYSLELPSYLGSNLFVKLN
What is the function of this protein?
Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
What are the official names of this protein?
NAD(P)H-hydrate epimerase, NAD(P)HX epimerase.
What is the protein family that this protein belongs to?
Belongs to the NnrE/AIBP family.
Protein: CXL10_MOUSE
Sequence: MNPSAAVIFCLILLGLSGTQGIPLARTVRCNCIHIDDGPVRMRAIGKLEIIPASLSCPRVEIIATMKKNDEQRCLNPESKTIKNLMKAFSQKRSKRAP
What is the function of this protein?
Pro-inflammatory cytokine that is involved in a wide variety of processes such as chemotaxis, differentiation, and activation of peripheral immune cells, regulation of cell growth, apoptosis and modulation of angiostatic effects (By similarity) (PubMed:28623423).  Plays thereby an important role during viral infections by stimulating the activation and migration of immune cells to the infected sites (PubMed:18624292, PubMed:19017990, PubMed:28468883).  Mechanistically, binding of CXCL10 to the CXCR3 receptor activates G protein-mediated signaling and results in downstream activation of phospholipase C-dependent pathway, an increase in intracellular calcium production and actin reorganization.  In turn, recruitment of activated Th1 lymphocytes occurs at sites of inflammation (By similarity).  Activation of the CXCL10/CXCR3 axis also plays an important role in neurons in response to brain injury for activating microglia, the resident macrophage population of the central nervous system, and directing them to the lesion site.  This recruitment is an essential element for neuronal reorganization (PubMed:15456824).
What are the official names of this protein?
C-X-C motif chemokine 10, 10 kDa interferon gamma-induced protein, Gamma-IP10, IP-10, C7, Interferon-gamma induced protein CRG-2, Small-inducible cytokine B10.
What is the protein family that this protein belongs to?
Belongs to the intercrine alpha (chemokine CxC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RNY_LEUMM
Sequence: MVVTIISVFFAIVIGLGIGYYVRKSQDAHKVISAEQMATNILEQANNEAKSLKRAAEVDAKDLAQTYRNQVNDSYNDRQKHLQQQEQRLEDRINNLDKKDAALNQRDASLIQKENQVQTRLDDADKKEVLAQKLLTTQQDKLEEIAQLSPDEAKKQILSETKASLTRQRAALIKEAEEEATSEAEKRARNIIVQAIQRSSADSVADVTVSVVNLPSEDMKGRIIGREGRNIRTLESLTGIDLIIDDTPESVVLSGFDPVRREIAKMALDALVADGRINPSRIEEMVEKSRRQMDETIREKGEQAVFELGLRGMHPDLIKMIGRMNYRTSYGQNVLQHSIEVAKLAGMMAAELKMDVALAKRAGLIHDIGKAVDAEVEGSHVELGVRLAEKFNEKPIVINAIASHHGDVAAISPIAELVAAADAISAARPGARSESLENYVQRLKDLEAIANNNQEVHTAYAIQAGREVRVIVEPTKVTDLQAKVLAHDIKSDVEEKLEYPGHIKVTVIRETRAIDYAH
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: FRIZ2_DROME
Sequence: MRHNRLKVLILGLVLLLTSCRADGPLHSADHGMGGMGMGGHGLDASPAPGYGVPVIPKDPNLRCEEITIPMCRGIGYNMTSFPNEMNHETQDEAGLEVHQFWPLVEIKCSPDLKFFLCSMYTPICLEDYHKPLPVCRSVCERARSGCAPIMQQYSFEWPERMACEHLPLHGDPDNLCMEQPSYTEAGSGGSSGGSGGSGSGSGSGGKRKQGGSGSGGSGAGGSSGSTSTKPCRGRNSKNCQNPQGEKASGKECSCSCRSPLIFLGKEQLLQQQSQMPMMHHPHHWYMNLTVQRIAGVPNCGIPCKGPFFSNDEKDFAGLWIALWSGLCFCSTLMTLTTFIIDTERFKYPERPIVFLSACYFMVAVGYLSRNFLQNEEIACDGLLLRESSTGPHSCTLVFLLTYFFGMASSIWWVILSFTWFLAAGLKWGNEAITKHSQYFHLAAWLIPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHLKTFVLAPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQGGVGAGVKADKLEKLMIRIGIFSVLYTVPATIVIGCYLYEAAYFEDWIKALACPCAQVKGPGKKPLYSVLMLKYFMALAVGITSGVWIWSGKTLESWRRFWRRLLGAPDRTGANQALIKQRPPIPHPYAGSGMGMPVGSAAGSLLATPYTQAGGASVASTSHHHLHHHVLKQPAASHV
What is the function of this protein?
Receptor for Wnt proteins.  Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes.  A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase.  Both pathways seem to involve interactions with G-proteins.  Required to coordinate the cytoskeletons of epidermal cells to produce a parallel array of cuticular hairs and bristles.
What are the official names of this protein?
Frizzled-2, dFz2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor Fz/Smo family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: 1433G_RAT
Sequence: MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDDGGEGNN
What is the function of this protein?
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways.  Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif.  Binding generally results in the modulation of the activity of the binding partner.
What are the official names of this protein?
14-3-3 protein gamma.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_METAR
Sequence: MIIDEILARKIFDSRGNPTIEVEVYTDDGNYGVAAAPAGASTGSYEAVAIPVDDAIAKLESEVIDQLIGEYAADQEEIDRLLHEIDGTDNFSNIGGNLSVALSMATAKAAAASFKMPLYRYLGGAFPTMPYPLGNVLGGGAHAKGATDIQEFLVTPIGAPNIDQAVYANTLVHKRVKKLLTEAGIICHKGDEGGWAPQIKDSKAFEIVSKAVDEVSGELGFEIRFGLDVAATELWDGNNYVYKDTKRTTEQQIDYIAGLIDEYNLYYVEDALQENDYEGFARLTEMVGDRCLICGDDLFVTNVSRIEKGIENLSGNAILIKPNQIGTVTDTYNAIRLGRQYGYSTVMSHRSGETTDNTIAHLAVAFGCELIKTGVVGGERIAKLNELIRIGEEIGNDRMTESPL
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: TERM_BPPH2
Sequence: MARSPRIRIKDNDKAEYARLVKNTKAKIARTKKKYGVDLTAEIDIPDLDSFETRAQFNKWKEQASSFTNRANMRYQFEKNAYGVVASKAKIAEIERNTKEVQRLVDEKIKAMKDKEYYAGGKPQGTIEQRIAMTSPAHVTGINRPHDFDFSKVRSYSRLRTLEESMEMRTDPQYYEKKMIQLQLNFIKSVEGSFNSFDAADELIEELKKIPPDDFYELFLRISEISFEEFDSEGNTVENVEGNVYKILSYLEQYRRGDFDLSLKGF
What is the function of this protein?
Hydrolyzes host peptidoglycans during virus entry.
What are the official names of this protein?
Primer terminal protein, TP, DNA terminal protein, Gene product 3, gp3, Protein p3, Terminal protein.
What is the protein family that this protein belongs to?
Belongs to the phi29likevirus DNA terminal protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=Associates with the host bacterial nucleoid through its N-terminal region.
Protein: YVED_VACCC
Sequence: MEVNNKKLINSFVGRAENFRRYDTYLPENDPLAMNSVFTFSSYTGIGPLYRDMRNSNFLSNPNEMG
What are the official names of this protein?
Uncharacterized 7.6 kDa protein.
Protein: VE6_HPV60
Sequence: MQMEEDRFPTTVADYCSEFDIPLKDLKLKCVFCRFYLTEQQLAAFYIKNLKLVWKNRYCFACCTPCLRLTAKFEAENYFQCMCKGEVLEVLTRIPLSSLSVRCFDCLTLLSFAEKIDCIISGQNFYLVRGRWRSYCRNCIEK
What is the function of this protein?
Plays a major role in the induction and maintenance of cellular transformation.  E6 associates with host UBE3A/E6-AP ubiquitin-protein ligase and modulates its activity.  Protects host keratinocytes from apoptosis by mediating the degradation of host BAK1.  May also inhibit host immune response.
What are the official names of this protein?
Protein E6.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E6 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: OBG_LACJO
Sequence: MFVDQTKIDVQAGKGGDGAVAFRHEKYVPLGGPAGGDGGRGGSIILVADSGLRTLMDFRFRRKFKADNGENGRIKSQYGRGAKDVRLKVPMGTSVYDFNTGELLGDLVENGQELVVAHGGKGGRGNIHFATPTRTAPEIAENGEPGEFRTLRLELKVLADVGLVGFPSVGKSTLLSVVTKAKPKIAAYEFTTLTPNLGMVVLPDGRDFSMADLPGLIEGASKGVGLGIQFLRHVERTKVILHLVSMDPNNGRDAYEDYETIRKELAGYTKDLTTKKEIIVATQMDIPGSEEKFAEFKKKLGDKTVYPISSVTHKGVSELMGKTADLVEEVAKEEAEKPAEIKVAEKEYVYKKPEDEGFKVERTGEHSFVVTGNKLERLVQRTNLDHTDGIMLLARKLKRLGVDEALRENGAVTGDDVSIADFTFEFVD
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHX2_ARATH
Sequence: MDPKLLLCLPQGDELFNPLNTMFIQMACILVFSQLFYLLLKPCGQAGPVAQILAGIVLSPVLLSRIPKVKEFFLQKNAADYYSFFSFALRTSFMFLIGLEVDLHFMRRNFKKAAVITLSSFVVSGLLSFASLMLFIPLFGIKEDYFTFFLVLLVTLSNTASPVVVRSIADWKLNTCEIGRLTISCALFIELTNVVLYTIIMAFISGTIILELFLFLLATVALILINMVLAPWLPKRNPKEKYLSKAETLVFFIFLLIIGITIESYDVNSSVSVFAIGIMFPRQGKTHRTLIQRLSYPIHEFVLPVYFGYIGFRFSIIALTKRFYLGIVIIVIVTIAGKFIGVISACMYLKIPKKYWLFLPTILSVKGHVGLLLLDSNYSEKKWWTTTIHDMMVAALVITTLVSGVLASFLLKTREKDFAYEKTSLESHNTNEELRILSCAYGVRHARGAISLVSALSGSRGASDPFTPLLMHLVPLPKKRKSELMYHEHDEDGGNANGDDEFGTNEGLEINDSIDSFAKDSKILIQQVKLVTQMLNMHEEICNATEDLRVSIVFLPFHKHQRIDGKTTNDGELFRQMNRNVLRHGPCSIGIFVDRNITGFQQPHGFDSVQHVATLFFGGPDDREALALCRWLANNTLIHLTVIQFVSEESKAETPVGNAMTRDNNEVFMEVLGRNQTEQETDRSFLEEFYNRFVTTGQVGFIEKLVSNGPHTLTILREIGEMYSLFVVGKSTGDCPMTVRMKDWEECPELGTVGDFLASSLDVNASVLVVQRQRHSHDSFIDD
What is the function of this protein?
May operate as a cation/H(+) antiporter.
What are the official names of this protein?
Cation/H(+) antiporter 2, Protein CATION/H+ EXCHANGER 2, AtCHX2.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. CHX (TC 2.A.37.4) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.