PharMolix/UniProtQA huggingface dataset:
Protein: HAT9_ARATH
Sequence: MGFDDTCNTGLVLGLGPSPIPNNYNSTIRQSSVYKLEPSLTLCLSGDPSVTVVTGADQLCRQTSSHSGVSSFSSGRVVKRERDGGEESPEEEEMTERVISDYHEDEEGISARKKLRLTKQQSALLEESFKDHSTLNPKQKQVLARQLNLRPRQVEVWFQNRRARTKLKQTEVDCEFLKKCCETLADENIRLQKEIQELKTLKLTQPFYMHMPASTLTKCPSCERIGGGGGGNGGGGGGSGATAVIVDGSTAKGAFSISSKPHFFNPFTNPSAAC
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
Homeobox-leucine zipper protein HAT9, Homeodomain-leucine zipper protein HAT9, HD-ZIP protein 9.
What is the protein family that this protein belongs to?
Belongs to the HD-ZIP homeobox family. Class II subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: P2C61_ORYSJ
Sequence: MMARWCVGWPAAARGGRDELTWQAELTAHAAGEFSMAAAQANAVMEDQAQVMASPGATLVGVYDGHGGPDASRFLRSRLFPLIHEFAAERGGAVDADVIRKAFLAADEEYLQLLRWSLPNMSRAAASGSCCLLGAISGDTLYVANAGDSRAVLGRRAAAGQTVAERLSTEHNVASEEVRRELAALHPDDGEVVVHARGAWRVKGIIQVARAIGDVYLKTPEFKRDPAVQRLCSAAAAVELARPVVTAEPSIHARKLKAGVDLFVVFASDGLWEHLSDEAAVQLVSKSSTRRGVAARLVQAALGEAARKREVRRGDLRRIERGVRRHFHDDITAVVVFLDLDDDGGRRARRRGRVVDSSSSSCSNTPLDVYSLYNSTA
What are the official names of this protein?
Probable protein phosphatase 2C 61, OsPP2C61.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: ENO_THEAB
Sequence: MYIEIIDVFAREVLDSRGNPTVEVEVMLEDGSIGRAIVPSGASTGKFEALELRDGDKKRYLGKGVLKAVENVNELIAPKLLGLNAYDQVYIDNVLLELDGTENKSKLGANAILGVSMAVARAAANSLQLPLYKYLGGVNAKVLPVPLMNVINGGAHADNNLDIQEFMIVPAGAPSFREALRYGAETFHALKKILKEAGHVTAVGDEGGFAPNLKNNEEAIQVLIQAIQSAGYEPGKDIFIALDVAASEFYNEETGKYFIDGSEKTVDELIEYYKSLIEKYPIISIEDPFDQEDWEAYQKFNKEVGNKVQIVGDDLYVTNVKRLQKGIELKASNSILIKLNQIGSVTETLNAIELAKTNNMTNVISHRSGETEDTFIADLAVATNAGLIKTGSLSRSERIAKYNQLLRIEEELGDVAQYRGLDAFYSIKR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RAD50_METMA
Sequence: MKLKNLYIENIRSYKKLDFTFEDGVTVISGVNGSGKSSLLEACFMGLFGSKILSKDFVLADMIFKGAESAKIHLGFEHLGREYLIEQAFRYSLKSENASNSRCVLFADGENIVDQATRTYEEVCALLNMDEEAYRNCAYIRQGEIDVLINAKPRDRQRMIDDLLQLGKLEEYRERAGYAKTAVRRLERDAKNSFLGVKAEIEGIESTEPVAAVNRLRQKVKETDAILEELNKKKEFAAARKGELDLRIAEYRERLQEIEVLKQAIRKSQEDKAACFKEKETFSEEVQVQRRVLLELGEENSGMREECGFGDLEIEALLLQQEKSESSAREKVNSGSKELALLLKEEETGVQALRELEKDKVETERVLVECRTSIGAANKEIEGYRANIKQLEEENKRLREKAGFGAAGEIASVIKELEEKESLLRDRKNEVSTKLGFALKEKESGDASLRELDSEMQSCRVAVSKGKSEIEALEKEIRDNSKAVLDFQEQKSEVFAGLKALGFTEEQLENLEDFNELLLENKNRLHGKEKELEVTLREIENTLRKNRELLAEGKCPTCGQELKGSGIACTAEECEEKKEKLSLELADIKLQRAELEKKLNRLKEAKKLEKQAYDYDIEIEKLLEKAKASEKLIDTHRTRIEEDSLKLESSGKRKQELEAAGSKLLLDIKALREQEKAAQKVHLESEKALREAKVFERKLAENASEIESLNGKIRTSLALIENYGQRLGELNEKLKAFAEKETQSKEKLEALELTLETARKNEEEAKKAHIESARLLGEAKKLQANLLRMQNIKHKISEFEAGIGNLAEKIGFFDREIVERSDRIRQLEGKLEGNRLEELQQKLARFEEAQVNITEKIREITAEKDTLLKEIGMIENSLKRLKELKEELKALENKRLYLEAVYNNADELENTYMRVRADMRARNIGALSILLNEMFSFMYTNNAYSHIELDPEYNLTVYRKDGTPLEPKLLSGGERAIFNLVLRCAIYRLLALGFGGDRPDGLPPMILDEPTVFLDRGHVRQLLKLIDMMRSIGVGQIIVVSHDESLIDSADHVFQVEKDPLTNMSSITKI
What is the function of this protein?
Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair.  The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA.  Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex.
What are the official names of this protein?
DNA double-strand break repair Rad50 ATPase.
What is the protein family that this protein belongs to?
Belongs to the SMC family. RAD50 subfamily.
Protein: G6PI_CERS1
Sequence: MKQIWQALKAHQQAVEHRGILDLFTDPRRAETFSTRLGDMLFDWSKTNIDHTARDLLIDLAGAAGVAEKREAMFSGEKINETEGRAVLHTALRNMDRPVQVDGVDVTPALRETHARMQAFVRDLRSGRFTGQGGPITDVVNIGIGGSDLGPAMACLALAPYADGPRCHFVSNVDGAHIHDTLQDLDPATTLVIVASKTFTTIETMTNAETAKRWMATRVSDPAAQFAAVSTAADRTAAFGIDASRVFGFEDWVGGRYSMWGPIGLALMIAIGPEAFDAFLAGGAEMDRHFREAPFAENLPVLLALVGLWHNQICGHATRAVLPYDQRLARLPAYLQQLEMESNGKRVAMDGHELTHHSGPIVWGEPGTNGQHAFYQLIHQGSRIVPCEFLVAREGHEPDLAHQHLLLVSNCLAQSEALLRGRSVEEARAVLAKKGLTGSELERQARHRVFPGNRPSTVLAYEKLTPATLGRIVALYEHRVFVEGVILGINSYDQWGVELGKELALALQPMLEGRAGTEGKDGSTAQLVAYLRS
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPS1_HUMAN
Sequence: MLDPSSSEEESDEIVEEESGKEVLGSAPSGARLSPSRTSEGSAGSAGLGGGGAGAGAGVGAGGGGGSGASSGGGAGGLQPSSRAGGGRPSSPSPSVVSEKEKEELERLQKEEEERKKRLQLYVFVMRCIAYPFNAKQPTDMARRQQKISKQQLQTVKDRFQAFLNGETQIMADEAFMNAVQSYYEVFLKSDRVARMVQSGGCSANDSREVFKKHIEKRVRSLPEIDGLSKETVLSSWMAKFDAIYRGEEDPRKQQARMTASAASELILSKEQLYEMFQNILGIKKFEHQLLYNACQLDNPDEQAAQIRRELDGRLQMADQIARERKFPKFVSKEMENMYIEELKSSVNLLMANLESMPVSKGGEFKLQKLKRSHNASIIDMGEESENQLSKSDVVLSFSLEVVIMEVQGLKSLAPNRIVYCTMEVEGGEKLQTDQAEASKPTWGTQGDFSTTHALPAVKVKLFTESTGVLALEDKELGRVILHPTPNSPKQSEWHKMTVSKNCPDQDLKIKLAVRMDKPQNMKHSGYLWAIGKNVWKRWKKRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQPGLEGGRAFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDAPISQFYADRAQKHGMDEFISSNPCNFDHASLFEMVQRLTLDHRLNDSYSCLGWFSPGQVFVLDEYCARNGVRGCHRHLCYLRDLLERAENGAMIDPTLLHYSFAFCASHVHGNRPDGIGTVTVEEKERFEEIKERLRVLLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKTVIRKCLEQAALVNYSRLSEYAKIEENQKDAENVGRLITPAKKLEDTIRLAELVIEVLQQNEEHHAEPHVDKGEAFAWWSDLMVEHAETFLSLFAVDMDAALEVQPPDTWDSFPLFQLLNDFLRTDYNLCNGKFHKHLQDLFAPLVVRYVDLMESSIAQSIHRGFERESWEPVKSLTSNLPNVNLPNVNLPKVPNLPVNIPLGIPQMPTFSAPSWMAAIYDADNGSGTSEDLFWKLDALQTFIRDLHWPEEEFGKHLEQRLKLMASDMIESCVKRTRIAFEVKLQKTSRSTDFRVPQSICTMFNVMVDAKAQSTKLCSMEMGQEHQYHSKIDELIEETVKEMITLLVAKFVTILEGVLAKLSRYDEGTLFSSFLSFTVKAASKYVDVPKPGMDVADAYVTFVRHSQDVLRDKVNEEMYIERLFDQWYNSSMNVICTWLTDRMDLQLHIYQLKTLIRMVKKTYRDFRLQGVLDSTLNSKTYETIRNRLTVEEATASVSEGGGLQGISMKDSDEEDEEDD
What is the function of this protein?
Calcium-binding protein involved in exocytosis of vesicles filled with neurotransmitters and neuropeptides.  Probably acts upstream of fusion in the biogenesis or maintenance of mature secretory vesicles.  Regulates catecholamine loading of DCVs.  May specifically mediate the Ca(2+)-dependent exocytosis of large dense-core vesicles (DCVs) and other dense-core vesicles by acting as a PtdIns(4,5)P2-binding protein that acts at prefusion step following ATP-dependent priming and participates in DCVs-membrane fusion.  However, it may also participate in small clear synaptic vesicles (SVs) exocytosis and it is unclear whether its function is related to Ca(2+) triggering (By similarity).
What are the official names of this protein?
Calcium-dependent secretion activator 1, Calcium-dependent activator protein for secretion 1, CAPS-1.
What are the subcellular locations of this protein?
Synapse. Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle membrane; Peripheral membrane protein. Note=Membrane-associated to vesicles. Strongly enriched in synaptic fractions. Preferentially binds to dense core vesicles but not to synaptic vesicles. Binds phosphoinosides, with a strong selectivity for PtdIns(4,5)P2 over PtdIns(3,4,5)P3. Probably localizes to different vesicles compared to CADPS2.
Protein: IHFA_BUCAI
Sequence: MVLTKAAISENLFEKLQLTKKESKEFVEFFFEEVRKSLEKGEAVKLSGFGNFQIKKKKARPGRNPRTGEIFLITARRVVTFKAGQKLKNKINNYLIKKNNNF
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: RL14_FUSNN
Sequence: MVQQQTILNVADNSGAKKLMVIRVLGGSRKRFGKIGDIVVASVKEAIPGGNVKKGDIVKAVIVRTRKETRRDDGSYIKFDDNAGVVINNNNEPRATRIFGPVARELRARNFMKILSLAIEVI
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: AMDB_XENLA
Sequence: MDMASLISSLLVLFLIFQNSCYCFRSPLSVFKRYEESTRSLSNDCLGTTRPVMSPGSSDYTLDIRMPGVTPTESDTYLCKSYRLPVDDEAYVVDYRPHANMDTAHHMLLFGCNVPSSTDDYWDCSAGTCNDKSSIMYAWAKNAPPTKLPEGVGFQVGGKSGSRYFVLQVHYGDVKAFQDKHKDCTGVTVRITPEKQPLIAGIYLSMSLNTVVPPGQEVVNSDIACLYNRPTIHPFAYRVHTHQLGQVVSGFRVRHGKWTLIGRQSPQLPQAFYPVEHPLEISPGDIIATRCLFTGKGRMSATYIGGTAKDEMCNLYIMYYMDAAHATSYMTCVQTGNPKLFENIPEIANVPIPVSPDMMMMMMMGHGHHHTEAEAETNTALQQPKREEEEVLNQDVHLEEDTDWPGVNLKVGQVSGLALDPKNNLVIFHRGDHVWDENSFDRNFVYQQRGIGPIQESTILVVDPNTSKVLKSTGQNLFFLPHGLTIDRDGNYWVTDVALHQVFKVGAEKETPLLVLGRAFQPGSDRKHFCQPTDVAVDPITGNFFVADGYCNSRIMQFSPNGMFIMQWGEETSSNLPRPGQFRIPHSLTMISDQGQLCVADRENGRIQCFHAKTGEFVKQIKHQEFGREVFAVSYAPGGVLYAVNGKPYYGDSTPVQGFMLNFSNGDILDTFIPARKNFEMPHDIAAGDDGTVYVGDAHANAVWKFSPSKAEHRSVKKAGIEVEEITETEIFETHMRSRPKTNESVGQQTQEKPSVVQESSAGVSFVLIITLLIIPVVVLIAIAIFIRWRKVRMYGGDIGHKSESSSGGILGKLRGKGSGGLNLGTFFATHKGYSRKGFDRLSTEGSDQEKDDDDDGSDSEEEYSAPPIPPVSSS
What is the function of this protein?
Bifunctional enzyme that catalyzes 2 sequential steps in C-terminal alpha-amidation of peptides.  The monooxygenase part produces an unstable peptidyl(2-hydroxyglycine) intermediate that is dismutated to glyoxylate and the corresponding desglycine peptide amide by the lyase part.  C-terminal amidation of peptides such as neuropeptides is essential for full biological activity (By similarity).
What are the official names of this protein?
Peptidyl-glycine alpha-amidating monooxygenase B, PAM-B, Peptide C-terminal alpha-amidating enzyme II, AE-II, Peptidyl-glycine alpha-amidating monooxygenase II.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the copper type II ascorbate-dependent monooxygenase family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle membrane; Single-pass membrane protein. Note=Secretory granules.
Protein: PYRH_STRR6
Sequence: MKMANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSLGIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQTAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILMAKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNMNQSGNIKRVVFGENIGTTVSNNIEEKE
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMFO_STAES
Sequence: MTQKVNVVGAGLAGSEAAYQLAQRGIKVNLIEMRPVKQTPAHHTDKFAELVCSNSLRGNALTNAVGVLKEEMRHLDSLIITSADKARVPAGGALAVDRHDFAGYITDTLRNHPNITVLNEEVNHIPEGYTIIATGPLTTEHLAQEIVDITGKDQLYFYDAAAPIIEKDSINMDKVYLKSRYDKGEAAYLNCPMTEEEFNRFYDAVLEAEVAPVNEFEKEKYFEGCMPFEVMAERGRKTLLFGPMKPVGLEDPKTGKRPYAVVQLRQDDAAGTLYNIVGFQTHLKWGAQKEVIRLIPGLENVDIVRYGVMHRNTFINSPDVLNEKYELKGHDNLYFAGQMTGVEGYVESAASGLVAGINLAHKILDKGEVIFPRETMIGSMAYYISHAKNEKNFQPMNANFGLLPSLEKRIKDKKERYETQAKRALEYLDNYKQTL
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASTD_CAUSK
Sequence: MSGGLFIDGVWRAGAGAQATSVDPTTGEVIWRQATASTAEVAAAVEAARKAFPAWADRSREERIAVLRRYKDVLVARTGTFAEALSRETGKALWETKAELGSMAGKVEASIKAYDERTGEHANDMAFGRAVLRHRAHGVMAVLGPFNFPGHLPNGHIVPALLAGDTVVFKPSEETPLAGQLLVEALEEAGVPAGVINLVQGGREVGQALIDQEIDGLLFTGSAAAGAFFRRHFADRPDVILALELGGNNPLVVWDAGDPEAVAALIVQSAFITTGQRCSCARRLIVSDDAAGRAVIDAVAALSERLVIGPWNGGQEPFMGPLISDRAAAMALAGAKAMPGQTLRAMTSVDGLSRAFVSPGLVDVTGETVPDEELFAPLLQVRRVGSFEEAIAAANATRYGLSAGLVSNETAHWDRFLTRIRAGVVNWNRPTTGAAGTMPFGGLGNSGNHRPSAYYAADYCAYPVASFEAENVTNTLGDIKGLRA
What is the function of this protein?
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
What are the official names of this protein?
N-succinylglutamate 5-semialdehyde dehydrogenase, Succinylglutamic semialdehyde dehydrogenase, SGSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. AstD subfamily.
Protein: KAX71_PANIM
Sequence: RGSVDYKDDDDKTISCTNPKQCYPHCKKETGYPNAKCMNRKCKCFGR
What is the function of this protein?
Potent inhibitor of the A-type voltage-gated potassium channels.  Most potent inhibitor of Kv1. 2/KCNA2 channels.  Reversibly block the Shaker B potassium-channels (Kv1. 1 sub-family).
What are the official names of this protein?
Potassium channel toxin alpha-KTx 7.1, Pandinotoxin-alpha, Potassium channel-blocking toxin 2, Pi-2, Pi2, Toxin PiTX-K-alpha.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 07 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: IXTPA_VIBVU
Sequence: MKKIVLATGNQGKVREMADLLADFGFDVVAQSEFNVSEVAETGTTFIENAIIKARHAAKETGLAAIADDSGLEVDFLQGAPGIYSARYAGEKASDQENLEKLLTAMEGVPEAQRTARFHCVLVLMRHENDPTPIVCHGKWEGRILTQAHGDNGFGYDPIFFVPEDNCASAELEPVRKKQLSHRGKALKQLFATLREQPLV
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: YBXB_BACSU
Sequence: MSEHYYSEKPSVKSNKQTWSFRLRNKDFTFTSDSGVFSKKEVDFGSRLLIDSFEEPEVEGGILDVGCGYGPIGLSLASDFKDRTIHMIDVNERAVELSNENAEQNGITNVKIYQSDLFSNVDSAQTFASILTNPPIRAGKKVVHAIFEKSAEHLKASGELWIVIQKKQGAPSAIEKLEELFDEVSVVQKKKGYYIIKAKKV
What are the official names of this protein?
Uncharacterized protein YbxB, ORF23, P23.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: Y143_CAUVC
Sequence: MAAGVRQSRGTAARKVGRRAEVIAALWLMAKGYRILGFRLATPLGEIDLLAQRGKVLAVVEVKQRTTIEDALDAVKPTQRERLRRAATHLAAHRAGLRDLLVRLDLIAMAPGRPPRHLPDAWGGA
What are the official names of this protein?
UPF0102 protein CC_0143.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: Y433_ARCFU
Sequence: MMLVQLRQVGVIRSPYKNFSKAPHQGRFSKETVEIEIFPEFEDGLKDIETCTHLIVLYWLDRANRDALLVVPPHDSREHGVFATRSPHRPNPIGFAVVELLERDGRVLKVKGLDALDGTPVVDIKPYSSTIDSVGNAKIGWFEEANPQSKLTRLLLRAKEFHGHICPFVALGVRMSVIAMEKLGVEEDAMASVGEDILAIVECNNCLTDGVQVATGCTLGNNSLIYLDLGKNALTIVRRKDWKGVRVYVNAENVRKYFSKEALELFNKVIVRREGSEEDAKRLSEFWEETGWKMLEIPEEEFKVEFVEVQPIERAPIFENKRCEKCGELAMATRVKDGLCLRCAGSYYAVVGRGIVKFDGEMREVV
What are the official names of this protein?
Probable S-adenosyl-L-methionine-binding protein AF_0433.
What is the protein family that this protein belongs to?
Belongs to the tRNA methyltransferase O family.
Protein: RL13_BURL3
Sequence: MKTFSAKAHEVTREWYVIDATDKVLGRVASEVARRLRGKHKPEFTPHVDTGDFIIIINASKLKVTGNKTLDKKYYRHSGYPGGIYETTFGKMQERFPGRALEKAVKGMLPKGPLGYAMIKKLKVYAEATHPHSAQQPKALEI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: SSRP_BIFAA
Sequence: MAKEQGTKPIAQNKKARHDYAIEDKYEAGLVLTGTEVKSLREGRASLAESFITIDRRGEMWLEGANIPEYLNGTWNNHAPKRKRKLLLHAAQIDKLARQTQAKGFTIIPLSLYFKDGRVKVEIALARGKKEFDKRQSLREEQDKREALRAMRYANKQVR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: IMPO_ENCCU
Sequence: MREETRQIFLQTIDSDAGKRSIAEAMLMDLEKQPGFVMSLPHTCMKDGDPIVKRVAAIYFKNAIIKQWRSNEYSEARKYLVENILDLFLYGDEVTRTAYNAILVNIFNNEKLSDLDGMFRKAAGFMRTSEANHVLTALNMYERVFDAEKIKYNLEQVLGLMFDTAGKDILEKVYGFLESGNYGMVKTGMIVLSKSYCYYSIPDFLSAIGTFSYVFNLSLRILNLEGSNEDLLESKKWAAYFMYKSCSKGIKKFYKKSELSEYITDMNRFQMVYATFLKIIQERSQQTIDIELYAIDFFVLLTSDADFFRYMEPNLSYFISGYILPLYSLSDSEEDDFENDPDKYLREKYNFFGNGLRSSLNTLFCEIISKVKQKEETFQGIISYLLSILGGSKETPSRDNIRAAYGSFFLLASIKSTLMKKARNVLEYIVANHVIPALRGNSCILKSQACYFLSTIEEDLPINGLALEALDNTHKLMKSSHRALMVESTLAMSFFLFNEASSEKFRQLIPETVESILSLSNTYNLEPLTMLLDSIIGYYPEEISKYAPELVGSISRITLSHLMNESDVGEDKQMVVSGFLRSIESLILSLDQRSLVLKYSYVNSYDVISFILKEEKSDFYQEALDILNGYVYMIKEIEGSMWGLFQMVLNLPIDEITVYSTEVADLIDNFITYGKTSVMDAGILGSICSVISKLCLCNEENFLDEDFIGGCRIIESIILNIGNELLSKDPSRLPLFISVAISGEKMIDEDGPAIVYALELIMNCFILRPKETIRILREQKYLQSFFEKLFSQKNKFKRVHDKKICMLFIGTICRLQDGALPELDVHGLGEVLVATVTSLPEAIRLRNQMKDDEDAPPPLVNTEDDQCLDASDISCTDILEEDIYFETELDKFEPFGYISSILSSPASGTYAEKIISTMTDEQKDSLSTVLNGERIIQKI
What is the function of this protein?
Active in protein import into the nucleus.
What are the official names of this protein?
Probable importin ECU10_0620, Probable karyopherin ECU10_0620.
What is the protein family that this protein belongs to?
Belongs to the importin beta family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: APT_PSESM
Sequence: MTFDQSNFKSLIRPVVDFPKPGVVFRDITPLFQSPKATRQVIDSFVQRYIDADFSHIGVMDARGFLIGSVVAYQLNKPLVLFRKQGKLPADVLSEAYQTEYGEAYLEVHADSLCEGNSVIMFDDLIATGGTLIAAANLIRRMGAQVHEAAAIIDLPELGGSKRLNDLNIPTFCLTEFALDEQ
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPF_BARQU
Sequence: MKTPFRKMDGLGNQIIVADMRESTHALTPQAILALAADPQTHFDQIMTIHSSTQKEADFRIEIWNADGSMAKACGNGTRCVIAWLTDHNLGESFRLETPAGIIEGKRQTDNLISVDMGCPNFNAKEMPVSREIADTNYVKITAGPLKDACLVSIGNLHAIFFVEDNIQQIPLEKYGPKLEHDPLFPERCNISIASVTSHKSLNLRTWERGAGLTKACGSAACASAVAAYRRGLTQRHIDVNLPGGTLNIVYREDNHIVMTGPTKYEFGGFLNPLTGTYKKDHF
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2A3_MOUSE
Sequence: MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHHKAKGK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A type 3, H2A-clustered histone 25.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: PTH_AZOPC
Sequence: MKYLVAGLGNVGQKYENSRHNIGFMILDALAKASSVVFTDKCYGAIASLKLKNKCLFLLKPSTYMNLSGNAIRYWLQKENIYSENLLILVDDLSLPFGSLRLKTKGSDGGHNGLKNIQYTLRTKYYNRLRFGIGNNFPSGCQINYVLDNFTKEEKKHLSERIEKAIEIVYSFCLSGSEITMNLFNK
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTI_GEOSW
Sequence: MRPLFIRNASQLVTLAGSSTAPLVKEKMNELHIIENGSVWVEDGKIAAVGTDEELSQQFQERIAEAEIVDATGKTVTPGLVDPHTHFVYAGSRESEFAMRLSGATYMEIMNAGGGIHATTKATREASKETLYEESKRRLDQFLLHGVTTVEAKSGYGLSIEHEVKQLTVAKQLDETHPVDVVSTFMGAHAVPAEWKDNPDGFVRVIVEEMIPKVSELGLAEFNDVFCERGVFTPEQARIILEAGKAYGLMPKIHADEIEPYGGAELAAEVGAVSADHLLRASDEGIRRMAEKGVIAVLLPGTAFFLMTKAANARKIIDAGAAVALSTDCNPGSSPTVSLPLIMNLGCLQMGMTPAEALAAVTINAAHAINRGHEIGSIEVGKKADLVLFDVPNYMQLIYHYGMNHTDTVVKNGRVVVKSGRLCY
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.