PharMolix/UniProtQA huggingface dataset:
Protein: PRDX2_HUMAN
Sequence: MASGNARIGKPAPDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSNRAEDFRKLGCEVLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTRRLSEDYGVLKTDEGIAYRGLFIIDGKGVLRQITVNDLPVGRSVDEALRLVQAFQYTDEHGEVCPAGWKPGSDTIKPNVDDSKEYFSKHN
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.  Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2).
What are the official names of this protein?
Peroxiredoxin-2, Natural killer cell-enhancing factor B, NKEF-B, PRP, Thiol-specific antioxidant protein, TSA, Thioredoxin peroxidase 1, Thioredoxin-dependent peroxide reductase 1, Thioredoxin-dependent peroxiredoxin 2.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_ECO8A
Sequence: MTDKIRTLQGRVVSDKMEKSIVVAIERFVKHPIYGKFIKRTTKLHVHDENNECGIGDVVEIRECRPLSKTKSWTLVRVVEKAVL
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: RPOC_BORA1
Sequence: MKALLDLFKQVSQDEQFDAIKIGLASPEKIRSWSYGEVRKPETINYRTFKPERDGLFCAKIFGPIKDYECLCGKYKRLKHRGVICEKCGVEVTVAKVRRERMGHIELASPVAHIWFLKSLPSRLGMVLDMTLRDIERVLYFEAWCVIEPGMTPLKRGQIMSDDDFLAKTEEYGDDFRALMGAEAVRELLRTIDIDREVETLRGELKATSSEAKIKKISKRLKVLEGFQKSGIKPDWMVMEVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPEIILRNEKRMLQEAVDSLLDNGRRGKAMTGANKRQLKSLADMIKGKSGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKLMALELFKPFIFNRLEMMGLATTIKAAKKLVESQEPVVWDILEEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQLEARTLMLASNNVLFPANGEPSIVPSQDIVLGLYYTTRERINGRGEGIFFADVAEVQRAYDNGEVELQTRITVRLKEHERDEQGEWQPVIRRHETTVGRALLSEILPRGLPFTVLNKALKKKEISRLINQSFRRCGLRDTVIFADKLMQSGFRLATRGGISIAMEDMLIPAAKEVILAEAGREVKEIDKQYSSGLVTSQERYNNVVDIWGKAGDKVGKAMMEQLATEPVVNRHGENVRQESFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVTQDLVITEVDCGTSHGYSMKALVEGGEVIEPLRDRILGRVAAVDIVNPDTQETEITAGTLLDEDLVDLIDRVGVDEVKVRTPLTCETRHGLCAHCYGRDLGRGSHVNVGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRSALASAVETKSNGTVGFASTMRYVTNAKGERVAISRSGELAIYDDNGRERERHKIPYGATVLVGDGDAVKAGTRLATWDPLTRPIVSEYGGAVRFENIEEGVTVAKQVDEVTGLSTLVVITPKTRGGKVVMRPQIKLVNDNGEDVRIAGTDHAVNISFPVGALITVRDGQQVAVGEVLARIPQESQKTRDITGGLPRVAELFEARSPKDAGMLAEVTGTVSFGKDTKGKQRLVITDLEGISHEFLIPKEKQVLVHDGQVVNKGEMIVDGPADPHDILRLQGIEKLATYIVDEVQDVYRLQGVKINDKHIEVIVRQMLRRVNITDPGDADFIPGEQVERSELLNENDRVIAEDKRPAQYDNVLLGITKASLSTDSFISAASFQETTRVLTEAAIMGKRDDLRGLKENVIVGRLIPAGTGLAYHLARKDKEALEAAEREAARQQANPFEEMPVAADIEVDVSLPFEGETPAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: Y4425_BURL3
Sequence: MTELMRIAALFAATALAEIVGCYLPWLVLKEGRPVWLLVPAALSLALFAWLLTLHPSAAGRTYAAYGGVYIAVALVWLRVVDGVALTRWDVAGAVLALGGMAVIALQPRA
What are the official names of this protein?
UPF0060 membrane protein Bcep18194_A4425.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PRM1_CANGA
Sequence: MRNYLLLRDRLTQVWLNKYSITVTILTAKIVLFNYFIIRILRYTEKYAISSCNGLDQVNRKVYDDLPIFVNTLGNYMIRKSMLESVEASLRGLEILIDASEGLLGFLVDLYLGTYACLLISAVDGAVDVATNTTEHILEAVNNTLIEATRGLDDGLNDLTSLINKGGNRLSSIFKSDNSVAASLSKVNFTVKGLRNIHLSSKINDQLQYMADKVPSFDDLKSETKDLISIPFYHVKREITKVNAESLLPDTKILYLRNNTDTTLYPICGQYIPNIKKVYEHLIHILKVGNILVAILGIFIALFMAIPSIQKEYQESKRLNNVQDEVSQYIDNKEFMSSGDNSSLNYSPFNDSKFNLAESYQRNFNPIARWMTIKMGKYFGNDETEYSERLQFCMLYIFSSRSSTIMAMGLIGLITVAIQLIVIQIISNYLSNTGKVHIQLQASNDEINKMIKSDINLWTSLANQYVNGTEANLNTQVFGWITNTTASVNATVAHAVDKIEYILASSFNNTPLYKPMKTVVGCAILRKLISVENAMTWINNEAHIKLPRINTTELINIAGHTKMLPSSNESHMFDQVEKIVNIARKTALNELYVPLALIGIWLTQIPMALLLSWRRCDTTGKT
What is the function of this protein?
Involved in cell fusion during mating by stabilizing the plasma membrane fusion event.
What are the official names of this protein?
Plasma membrane fusion protein PRM1.
What is the protein family that this protein belongs to?
Belongs to the PRM1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DMTA2_MOUSE
Sequence: MELRSELPSVPGAATAAATATGPPVASVASVAAAAAAAASLPVSVAGGLLRAPPLLLRAAEKYPRTPKCARCRNHGVVSALKGHKRYCRWKDCLCAKCTLIAERQRVMAAQVALRRQQAQEENEARELQLLYGTAEGLALAAANGIIPPRPAYEVFGSVCATDGGGPGAGAPAGSAGGAGGAEAKLQKFDLFPKTLLQAGRPDSPQPPPGKPLSPDGADSGPRTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPGSAGAGGGGEEDSPGSSSPLGSESGSEADKEEAEAAPTPGLGGGPGPRQRTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPLEKAAVSAAVEDAWPGRVEAAAAGGAGLPAPLQTGPTAPPHHRPLLAGAMTPGALGSLSSRSAFSPLQPNASHFGADAGAYPLGAPLGLSPLRLAYSAAAAHSRGLAFMAPYSTAGLVPTLGFRPPMDYAFSDLMRDRSAAAAAAVHKEPGYGGGLYGPMVNGTPEKQ
What is the function of this protein?
May be involved in sexual development.
What are the official names of this protein?
Doublesex- and mab-3-related transcription factor A2, Doublesex- and mab-3-related transcription factor 5.
What is the protein family that this protein belongs to?
Belongs to the DMRT family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PIG19_CLAP2
Sequence: MATMAHANTSHPLYVAGMAGNTNHMSPWGEDAHKRWLAALGPSSLRGPFAWQTCPQQRHPHQPDVSGPPGSGFGEQPSQDTPNPMFGATGPHQQHNFPSHPYAAHNSKEAHEAWLKVYQSVWGNTKHAGAWSGPWSPAAGGRQHHMSGGGGGGGPRWMGGPMPWTQCDETKKSFTPDIDVVETPESYSVQASLPGAKKEDVKVSWDPSTYELRIEGVVSRSVGNDEEGEKKTEQSGRFSLRERQTGKFCRTVYLGSQVDGDKIEEGGLSAGMDDGVLRIAVPRQGSGKGVKEITIV
What is the function of this protein?
Monooxygenase; part of the ergochrome gene cluster responsible for the typical purple-black color of the ergot sclerotia (Probable).  The ergochrome gene cluster produces several ergot pigments including the yellow ergochrome secalonic acid and its derivatives, as well as the red anthraquinones endocrocin and clavorubin (PubMed:28955461).  The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) CPUR_05437 (By similarity).  The atrochrysone carboxyl ACP thioesterase CPUR_05436 then breaks the thioester bond and releases the atrochrysone carboxylic acid from CPUR_05437 (By similarity).  The atrochrysone carboxylic acid is then converted to atrochrysone which is further transformed into emodin anthrone (By similarity).  The next step is performed by the anthrone oxygenase CPUR_05434 that catalyzes the oxidation of emodinanthrone to emodin (By similarity).  Emodin is further modified to yield monodictyphenone via several steps involving CPUR_05427, CPUR_05428, CPUR_05429 and CPUR_05430 (By similarity).  The short chain dehydrogenase/reductase CPUR_05418 then catalyzes the C-5 ketoreduction to give the xanthone skeleton of the monomeric units (PubMed:32105084).  Ergochromes formation requires further dimerization steps of different xanthone units, probably catalyzed by the cytochrome P450 monooxygenase CPUR_05419 (PubMed:28955461).  CPUR_05425, CPUR_05426 and CPUR_05431 are unique to Claviceps, thus it is likely that they are involved in further modification of xanthone units or in their dimerization (PubMed:28955461).  The yellow ergochromes and the red anthraquinone pigments endocrocin and clavorubin are products from the same PKS derived precursors and the latter are likely shunt products in the pathway of xanthone biosynthesis (PubMed:28955461).  It is proposed that atrochrysone carboxylic acid released from the PKS CPUR_05437 can also be converted to endocrocin anthrone which is further oxidized into endocrocin by CPUR_05435 (By similarity).  Endocrocin could be then modified to clavorubin, possibly by CPUR_05423 and CPUR_05431 (PubMed:28955461).  Clavorubin is the principal anthraquinone metabolite produced by the cluster with a much higher yield compared to endocrocin (PubMed:28955461).
What are the official names of this protein?
SHSP domain-containing protein CPUR_05420, Ergochrome biosynthesis cluster protein CPUR_05420.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
Protein: LCRD_YERE8
Sequence: MNPYDLEWLNRIGERKDIMLAVLLLAVVFMMVLPLPPLVLDILIAVNMTISVVLLMIAIYINSPLQFSAFPAVLLVTTLFRLALSVSTTRMILLQADAGQIVYTFGNFVVGGNLIVGIVIFLIITIVQFLVITKGSERVAEVSARFSLDAMPGKQMSIDGDMRAGVIDVNEARERRATIEKESQMFGSMDGAMKFVKGDAIAGLIIIFVNILGGVTIGVTQKGLAAAEALQLYSILTVGDGMVSQVPALLIAITAGIIVTRVSSEDSSDLGSDIGKQVVAQPKAMLIGGVLLLLFGLIPGFPTVTFLILALLVGCGGYMLSRKQSRNDEANQDLQSLLTSGSGAPAARTKAKTSGANKGRLGEQEAFAMTVPLLIDVDSSQQEALEAIALNDELVRVRRALYLDLGVPFPGIHLRFNEGMGEGEYLISLQEVPVARGELKAGYLLVRESVSQLELLGIPYEKGEHLLPDQETFWVSVEYEERLEKSQLEFFSHSQVLTWHLSHVLREYAEDFIGIQETRYLLEQMEGGYGELIKEVQRIVPLQRMTEILQRLVGEDISIRNMRSILEAMVEWGQKEKDVVQLTEYIRSSLKRYICYKYANGNNILPAYLFDQEVEEKIRSAVRQTSAGSYLALDPAVTESLLEQVRKTIGDLSQIQSKPVLIVSMDIRRYVRKLIESEYYGLPVLSYQELTQQINIQPLGRVCL
What is the function of this protein?
Could be involved in the secretion of the yop virulence proteins.
What are the official names of this protein?
Low calcium response locus protein D.
What is the protein family that this protein belongs to?
Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CKLF_MOUSE
Sequence: METPRPVVSRRPFCCTLKCFVKFLRLVVTVTSMIFFIVGQAPEPYIVITGFEVTVIFCFLVLYTCGLDKIMRSFFWPLLDVINSMVTALCMLIVSVLALIPETSTKTILGGVFGFLTVTCTIADCALMCQKLRFRPRQPYQKKSTNDIDDRE
What is the function of this protein?
May play an important role in inflammation and regeneration of skeletal muscle (By similarity).  Essential for embryonic development (PubMed:34446558).
What are the official names of this protein?
Chemokine-like factor.
What is the protein family that this protein belongs to?
Belongs to the chemokine-like factor family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL30_FRAT1
Sequence: MTQAKTFKVTLVKSLIGRKENHIASARGLGLRKINHTVEVLDTPENRGMANKIYYMVKIEG
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: TAL_NOVAD
Sequence: MKFFVDTADTAEIADLAATGLLDGVTTNPTLIAKAGKDFIEVTKEICGLVDGPVSAEVVALDHEGMMREAEVLRKIADNVCIKVPLTVDGLKTCKALTGEGTMVNVTLCFSANQALLAAKAGATFISPFVGRHDDNGFDGMDLIRDIRLIYDNYAFETQILVASIRHGVHVLESARIGADVITAPPAVIKGLFKHVLTDKGIEGFLADWAKTGQKIV
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y998_METJA
Sequence: MKSLYALIFLLFVIVVSYIFNGLWSVFNIKHVFWVNLFLLIAFHPQHLDGLIILLLIPLKIFSNFKLKLQCIIALVGILLTIIKGVIKSGFGWILRILFFFVRMMTVSFINLVVFSILLTSVYVLGYVAFLKPDDIQFGTLYTAFGGLALLGAGIKIIQHFIKQSEEIAQEEFKKWYETEVKNFMYSLFITAKNAFPKFLDDLLAKGVVSQEEYQNLIKLYSHILARILKNDEEKMKIPTF
What are the official names of this protein?
Uncharacterized protein MJ0998.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MNMG_TRIEI
Sequence: MNQTFDFQDEYDIIVVGAGHSGCEAALATARLGCHTLLLTLNLDKIAWQPCNPAVGGPAKSQLTHEVDALGGEIGKMADRTYLQKRILNSSRGPAVWALRAQTDKREYATIMRNIVENQENLRVRESMVTDLVLGDNEEIIGVETYFGVAFKCKAVILTTGTFLGGVIWVGNKSMPAGRAGEFSAIGLSETLNKLGFETGRLKTGTPARVDKRSVDYTDLEAQPGDEKVRWFTFDPEVWVEREQMCCYLTRTTPETHKLIRDNLHLSPVYGGWVDAKGPRYCPSIEDKIVRFADKHSHQIFIEPEGRDIPELYIQGFSTGLPEKLQLQMLQSLPGLENCLMLRPAYAVEYDYLPATQCYPTLMTKKIEGLFCAGQINGTTGYEEAAAQGLVAGINAVKFVKNEEMIIFPREQSYIGTLIDDLCTKDLREPYRMLTSRSEYRLILRSDNADQRLTPLGREIGLIDDRRWELFESKQANINSEKSRLNSTRIKELDEVAINIVADTHTKIKGSITLADLLRRPGFHYVDLEKYNLGNLDLKLVEKEGAEIDIKYSGYLQRQQNQIDQISRQKNRRLPTNLDYLSISTLSLEAREKLSKVQPLTIGQASRIGGVNPADINALLVYLEVQYRQFQLTSANV
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVD2_BORBR
Sequence: MSLHKHRSRMVTQGLTRTPHRAFLRATGFDDAALEKSMVGIVSTQGENTPCSMALGPQADRARLGVAAGGGVPVSFSTISISDGTSMNHAGMRMSLLSRETIADSVELVVRGHAYDALVAFAGCDKTLPAMMMAIVRLNVPAVFLYGGATLPGHAASGQVTILDTIEAVGRVQHGTMPAAELKAMERTCTPSAGSCPGQFTANTMAMVGEALGLSPLGSAMMPAVYSERLAIAQRAGEHVMRALAAGGPLPRQLVTRASLENACAAVAATGGSTNAALHIPAIAHEAGIAFTLDDVARVFKRTPLIADLQPGGRYLARDLHEAGGVPVVLKALLDGGHIDGSVLTLDGRTLAEALADTPAPDGKVVRACGQALHPTGGVAVLKGNLSPDGALLKIAGLKSLKFSGPARVFENEEACMRAVSTHAYQPGEVLVIRNEGPRGGPGMREMLSVTAALYGQGMGEKVALLTDGRFSGATRGLCIGYAGPEAAAGGPIALLRDGDMIHIDAEADTLDVALSDEELARRRAAYQAPPQARLAGALEKYAALVRPACLGAVTHSGQVDWPYETPEAE
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase 2, DAD 2.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: S20A1_FELCA
Sequence: MAFTGATLTTSTIAATAASGPLMDYLWMLILGFIIAFVLAFSVGANDVANSFGTAVGSGVVTLKQACILASIFETVGSVLLGAKVSETIRKGLIDVEMYNTTQQLLMAGSVSAMFGSAVWQLVASFLKLPISGTHCIVGATIGFSLVAKGQEGVKWSELIKIVMSWFISPLLSGIMSGILFFLVRAFILRKTDPVPNGLRALPVFYACTVGINLFSIMYTGAPLLGFDKLPLWGTILISVGCAVFCALIVWFFVCPRMKRKIEREIKSSPSESPLMEKKNSLKEDHEETKLSVSDIETRSPVSEVGSATVPLRAVVEERTVSFKLGDLEEAPERERLPSVDLKEETSIDSAMNGAVQLPNGNLVQFNQAVSNQMNSSGHYQYHTVHKDSGLYKELLHKLHLAKVGDCMGDSGDKPLRRNNSYTSYTMAICGMPLDSFRAKEGEQKGEEMEKLTWPNAESKKRIRMDSYTSYCNAVSDIHSASEMDMSVKAEMGLGDRKGSSSSLEEWYDQDKPEVSLLFQFLQILTACFGSFAHGGNDVSNAIGPLVALYLVYDTGDVSSKVATPIWLLLYGGVGICIGLWVWGRRVIQTMGKDLTPITPSSGFSIELASALTVVIASNIGLPISTTHCKVGSVVSVGWLRSKKAVDWRLFRNIFMAWFVTVPISGVISAAIMAVFKYVIL
What is the function of this protein?
Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport, such as absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis.  May play a role in extracellular matrix and cartilage calcification as well as in vascular calcification.  Essential for cell proliferation but this function is independent of its phosphate transporter activity.
What are the official names of this protein?
Sodium-dependent phosphate transporter 1, Feline leukemia virus subtype-B receptor, Phosphate transporter 1, PiT-1, Solute carrier family 20 member 1.
What is the protein family that this protein belongs to?
Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GLMU_HELAH
Sequence: MLSVIILAAGKGTRMHSSLPKTLHTLCGEPMLFYILETAFSISNDVHLILHHQQERIKEAVLERFKGVVFHTQIVEKYSGTGGAIMQEDKTPILTKHERILILNADMPLITKDALTPLLKSHNNAIGLLHLADPKGYGRVILENHQVRKIVEEKDANDEEKAIKSVNAGVYLFERKFLEKYLPKLHNQNAQKEYYLTDLTAFGINENEKIDAIFLEEEFFLGVNCQTERAKAEEIMLERLRKNAMDLGVVMQLPKSIYLEKGVSFKGECVLEQGVRLSGTCLIENAHIKAYSVIEESQIVNSSVGPFAHARPKSTICDSHVGNFVETKNAKLQGTKAGHLSYLGDCEIGKNTNVGAGVITCNYDGKKKHQTIIGENVFIGSDSQLVAPVTIGSNVLIGSGTTITKDIPSGFLSLSRTPQTNIENGYFKFFKKS
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y130_LISMO
Sequence: MKVNKFFKKTTHVLLVAGLTIGLTAPFTGTTAQAAADTVPIQILGINDFHGALETASKDASGSPIGGADYLATNLDNATNSFLQANPGATTDNAIRVQAGDMVGASPAVSGLLQDEPTMKVLQKMNFEVGTLGNHEFDEGLPEYKRILDGVSTNKFGPIVEAYPRVKSDMKIVAANVVNKGTNTVAEGFLPYYVKEIDGVKVGFIGIVTTEIPNLVLANHIKDYDFLDEAETIVKYSAELRGQGVNAIVVLSHVPALSTGNPNTGTKQDVAGEAANMMTKANELDPNNSVDLVLAGHNHQYTNGLVGKTRIVQSYNNGKAFSDVTGELDKTTGDFVSPPDAKITYNTRSVTPNADITAVTEDAKSRIEGVINETIGLANKDVISRDTNPDNKAIDDKESELGNMITDAQRYMANKAGADVDFAMTNNGGIRSDLTTRLANGQNEITWGAAQAVQPFGNILQVVEMTGADILEALNQQYLSNQTYFLQISGLKYTFTDTDDLDHAYKVASVTTEDGTPLKTDQKYKVVINDFLFGGGDGFSAFKKANLVTAIDPDTETFINYIKDQKAAGKVITAQKEGRKVYKSQAEIDKETKDAAIKAIKEATKINKLAEKDKTLTGTTLPGATVSVQKATANARMALAAGPNATADANGKFSVDVTSLNLKKGDQITTTITDPNGYSTTFQATVQAAATTPPDNGNGGTDNGNGNGNNGGTDGNGGTNNGNGSGTNGGTTTTEDPTTTTSNTSTTGTSSNTSLPTTGDTAGLATVFGVILTTTALYVLRKRS
What are the official names of this protein?
Cell wall protein Lmo0130.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor. Note=In the absence of SrtA in exponential phase some protein is still anchored to the cell wall while a very small amount is secreted, in stationary phase almost no protein accumulates; protein levels decrease in the srtA mutant, suggesting post-transcriptional regulation that involves SrtA.
Protein: ADT_ORYSJ
Sequence: MAEQANQPTVLQKFGGQFHLGSSFSEGVRARNICPSVSSYDRRFTTRSYMTQGLVNGGINVPMMSSSPIFANAPAEKGGKNFMIDFLMGGVSAAVSKTAAAPIERVKLLIQNQDEMIKAGRLSEPYKGIGDCFGRTIKDEGFASLWRGNTANVIRYFPTQALNFAFKDYFKRLFNFKKDKDGYWKWFGGNLASGGAAGASSLFFVYSLDYARTRLANDAKAAKGGGERQFNGLVDVYRKTLKSDGIAGLYRGFNISCVGIIVYRGLYFGMYDSLKPVVLTGSLQDNFFASFALGWLITNGAGLASYPIDTVRRRMMMTSGEAVKYKSSMDAFSQILKNEGAKSLFKGAGANILRAIAGAGVLSGYDQLQILFFGKKYGSGGA
What is the function of this protein?
ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell (By similarity).  Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane (By similarity).
What are the official names of this protein?
ADP,ATP carrier protein, mitochondrial, ADP/ATP translocase, Adenine nucleotide translocator, ANT.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PSBL_ORYSA
Sequence: MTQSNPNEQNVELNRTSLYWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: SYP32_ARATH
Sequence: MSARHGQSSYRDRSDEFFKIVETLRRSIAPAPAANNVPYGNNRNDGARREDLINKSEFNKRASHIGLAINQTSQKLSKLAKLAKRTSVFDDPTQEIQELTVVIKQEISALNSALVDLQLFRSSQNDEGNNSRDRDKSTHSATVVDDLKYRLMDTTKEFKDVLTMRTENMKVHESRRQLFSSNASKESTNPFVRQRPLAAKAAASESVPLPWANGSSSSSSQLVPWKPGEGESSPLLQQSQQQQQQQQQQMVPLQDTYMQGRAEALHTVESTIHELSSIFTQLATMVSQQGEIAIRIDQNMEDTLANVEGAQSQLARYLNSISSNRWLMMKIFFVLIAFLMIFLFFVA
What is the function of this protein?
Vesicle trafficking protein that functions in the secretory pathway.
What are the official names of this protein?
Syntaxin-32, AtSYP32.
What is the protein family that this protein belongs to?
Belongs to the syntaxin family.
What are the subcellular locations of this protein?
Golgi apparatus, cis-Golgi network membrane; Single-pass type IV membrane protein.
Protein: SMC2_DICDI
Sequence: MYIEDIIIDGFKSYANRTVIEGFDPTFNAITGLNGSGKSNILDSICFVLGISNLSQVRVDSLQELVYKKGQAGITKASVTITFNNSDKKQSPAGYEHLDKITVTRQVAIGGRNKYLINGHNAQLSRVQDLFHSVQLNVNNPHFLIMQGRITKVLNMKPPEILAMIEEAAGTRMFEMKKNSALNTIEKKQKKVDEITKVLAEEITPTLDKLRGERTSYMKFTNNQTLIDRLQRFIIAYEYYTYEKKLESSEFESFKAEIDKGQKRKKDLTLKSTDLKAKISELAKQREKETNLEEMDQQEQKLSKELVKYQTSHKHQKESLDKEEGAINNLANTREEIKQSIQQKQKEKQSMEKKIQSIVEENQQINAELKTLQNKHNTMTTGISTGADGSSAAEDGSYTEQLMEAKKTAVNAASEYKQAEFRVKHLQSELIAKRKAITQEQTDHKKLQAEQELVEREIQQLTRSIQELQLDNSKQQELTEKKRQLEPLVSKLREEVGNASAQLSGLEFNYTDPSKSFDRSKVKGIVANLITLKDVETATALEICASGKLYNIVIEDDETGKALLSKGQLKRRVTLLPLNKVEGRSIDPQKIKNAQKIAPNGAVKPAIEFVEYDKELQPAMNFVFGSTFIATDKKYAQKAAFDSSIKVRTISLEGDEYNPAGSLTGGSRPPSGSILTQIQRLNENNRCLRENQSQLEHINFELVQLKSVTDRFKQLEQQLNIKQHAASLIAQRFQLNPHHQLLESIKEMEKSIESDTQLITNSMIKEKEALEKVKQLESQVNDFQSIRESQLKDLEKKIQITKEKCIKSNKIVKGEQVFIEKLDLEIQEMDNELENLSKETQGNQGTISKMRKDVDTLARSISETNKQIQDIRETLSEIRKDMAQKNDAIRSLHQELEKIQSEITEIDMSTEKLKSRMNRVDKDRQEASKWLEAAIKKHTWIKNEKQLFNRPGSDFDFNATDPSKANSEYIKLQEEQEKLSKTINRKVMSMFEKAEQEYQELMEKKKIIENDKSKIEHVIRELDEKKNESLRTTWKKVNKDFGSIFSTLLPGTSAKLEPPEGQNELFGLEVKVAFGDVWKETLSELSGGQKSLLALSLILSLLLFKPAPMYILDEIDAALDLSHTQNIGMMLKQHFTSSQFIVVSLKEGMFTNANVLFETKFIDGVSKVHRTVFNKKDKQVGKKK
What is the function of this protein?
Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.  The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases (By similarity).
What are the official names of this protein?
Structural maintenance of chromosomes protein 2.
What is the protein family that this protein belongs to?
Belongs to the SMC family. SMC2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: TYRA_STAES
Sequence: MRNILFVGLGLIGGSLASNLKYHYSNFNILAYDSDYTQLDEALSIGIIDQKVNDYATAVEIADIIIFATPVEQTIKYLSELTNYNTKTHLIVTDTGSTKLTIQSFEKELLKHDIHLISGHPMAGSHKSGVLNAKKHLFENAYYILVFNEIENNEAATYLKKLLKPTLAKFIVTHANEHDFVTGIVSHVPHIIASILVHLSANHVKDHSLIEKLAAGGFRDITRIASSNAQMWKDITLNNQNHILSLLNEIKEQITGIENLIREQNSNSIYDFFVKAKDYRDQLPVKQHGAISTAYDLYVDIPDKPGMISQITNIISSHNISIINLKILEVREDIYGALQISFKSPEDRENAIKALANFDTYY
What are the official names of this protein?
Prephenate dehydrogenase, PDH.
What is the protein family that this protein belongs to?
Belongs to the prephenate/arogenate dehydrogenase family.