PharMolix/UniProtQA huggingface dataset:
Protein: PEPA_TALSN
Sequence: MVNSKTVVSALALSALAAAAPAPSSTTSFSINQVAVKKPAIHPAVKYAKALAKYHAEIPSNVASAAASAQSGSATNKPTADDEEYVTPITAGSSTLHLDFDTGSADLWTYSASTRGVGSHSTYDTSTGKKVSGASWQISYGDGSSASGVVYKDKVVVGGVTASSQAVEVATQVSSEFSQDTSNDGLLGLAFSSINTVSPTPQKTFYDNVKSSLAKPVFAVTLKHQAPGTYDFGFIDKSKYKGSLAYTNVDNSQGFWQFTADGYSIGGSGGGSSFSAIADTGTTLVLLDDSIVDEYYSQVQGAQNDSSQGGYVFDCSADLPDFGVQIGDYTAVIPGKYINYASTGSTCFGGIQSNSGIGFSILGDVFLKSQYVVFDGDNLQLGFAAQA
What is the function of this protein?
Secreted aspartic endopeptidase that allows assimilation of proteinaceous substrates.  The scissile peptide bond is attacked by a nucleophilic water molecule activated by two aspartic residues in the active site.  Shows a broad primary substrate specificity.  Favors hydrophobic residues at the P1 and P1' positions, but can also activate trypsinogen and hydrolyze the B chain of insulin between positions 'Gly-20' and 'Glu-21'.
What are the official names of this protein?
Penicillopepsin-1, Aspartic protease pepA.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: TTYH1_RAT
Sequence: MGAPPGYRPSAWVHLLHQLPRADFQLRPVPSGFAPRDQEYQQALLLVAALAGLGLGLSLIFIAVYLIRFCCCRPPEPPGAKSPPPGGGCVTWSCIAALLVGCAGIGIGFYGNSETSDGVSQLSSALQHANHTLSTIDDLVLETVERLGEAVRTELTTLEEVLSERVELVAATRGARRQAEAAAQHLQGLAFWQGVSLSPVQVAEDVTFVEEYRWLAYVLLLLLVLLVCLFTLLGLAKQSKWLVVVMTAMSLLVLVLSWGSMGLEAATAVGLSDFCSNPDTYVLNLTQEETGISSDILNYYFLCNQAVSNPFQQRLTLSQRALASIHSQLQGLEREASPQFPAAQKPLLSLEETLNVTERSFHQLVALLHCRSLHKDYGSALRGLCEDALEGLLFLMLFSLLSAGALATTLCSLPRAWALFPPSDDYDDTDDDDPFNPQESKRFVQWQSSI
What is the function of this protein?
Probable chloride channel.  May be involved in cell adhesion.
What are the official names of this protein?
Protein tweety homolog 1.
What is the protein family that this protein belongs to?
Belongs to the tweety family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PNPH_MOOTA
Sequence: MRIAIIGGSGVYDPGILTNIHEERVETPYGAAVLKVGTYHGEEIGFMPRHGDKHTVPPHKVNYRANIWALKMLKVERVLATAAVGSTNPEFRPGDFVIVNDFLDFTKTRTYTFFEGGETGVVHTDFTTPYCPELGQVLVETAARLGIKAHAGGVYACTEGPRFETPAEIRMIRQLGGDLVGMTNVPEVVLAHEVGLCYGLIAMVTNMAAGISSTPLSHEEVLEIMDQNGKNLRDLIMQAIPGIPRQRNCRCSLAAGKIEV
What is the function of this protein?
Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides.  Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules.  Involved in purine salvage.
What are the official names of this protein?
Probable 6-oxopurine nucleoside phosphorylase, Purine nucleoside phosphorylase, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
Protein: CH10_CHLCV
Sequence: MSDQATTLRIKPLGDRILVKREEEDSTARGGIILPDTAKKKQDRAEVLVLGTGKRDKDGNVLPFEVTVGDTVLIDKYAGQELTVDGEEYVIVQESEVMAVLK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, 11.2 kDa stress response protein, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CASP1_LACSI
Sequence: MTKSVRLEEGDASKVLVPVGSNKGVSVMDLVLRLVGIAGTLGAAIAMGTNEQTLPFFTRFVVFNAEYDDFRSFRLFVIVNAIVCAYFVLTLPLSIVHIMRSAARGSRILLIIMDTVMLALLTAGASAAASIVYLAHNGNTSTNWLPVCQQYGDFCQGASGSLIGSFGAVVVFILIILLGAIALSRHAKRVVL
What is the function of this protein?
Regulates membrane-cell wall junctions and localized cell wall deposition.  Required for establishment of the Casparian strip membrane domain (CSD) and the subsequent formation of Casparian strips, a cell wall modification of the root endodermis that determines an apoplastic barrier between the intraorganismal apoplasm and the extraorganismal apoplasm and prevents lateral diffusion (By similarity).
What are the official names of this protein?
Casparian strip membrane protein 1, LsCASP1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Very restricted localization following a belt shape within the plasma membrane which coincides with the position of the Casparian strip membrane domain in the root endodermis.
Protein: CH60_SHELP
Sequence: MAAKEVLFGNDARVKMLAGVNVLANAVKVTLGPKGRNVVLDKSFGAPLITKDGVSVAKEIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIVTEGLKAVAAGMNPMDLKRGIDKAVVAAVAELKTLSQECSDTKAIAQVGTISANSDESIGEIIATAMEKVGKEGVITVEEGQALENELDVVEGMQFDRGYLSPYFINKPETGSVELENPYILLVDKKISNIRELLPILEGLAKTGKPLMIIAEDVEGEALATLVVNNMRGIVKVAAVKAPGFGDRRKAMLQDIAILTGGTVIAEEIGLELEKATLEDLGTAKRVVITKDDTTIIDGTGEQEQISARVAQIKIQAEESTSDYDREKLQERMAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKIGELDVANEDQKHGVTIALRAMEAPLRQIATNAGEEASVVANNVKNGSGNYGYNAGSDVYGDMLEMGILDPTKVTRSALQFASSIAGLMITTEAMVGDVPQEAGAGDMGGMGGGMGGMGGMGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNAS1_HYSCR
Sequence: KESSAMKFERQHMDSSGSPSSNSNYCNEMMRRRNMTQDRCKPVNTFVHEPLADVRAVCFQKNVACKNGQTNCYQSNSLMHITDCRVTGSSKYPDCSYGMSQLERSIVVACEGSPYVPVHFDASVGPST
What is the function of this protein?
Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides.  Acts on single-stranded and double-stranded RNA (By similarity).
What are the official names of this protein?
Ribonuclease pancreatic, RNase 1, RNase A.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: ZAPD_BORPA
Sequence: MASVILYEYPFNERIRAYLRLEYLFDRLFFFAREGDARLHQIAVSSLFDLLDASERTDIKGAVLQDLERQRMALVGLRDHPGVAQDALEAMLRDMERVVAALAAQGKTGQALRENEWLVSLRGRLAVPGGATQVDMPSYHAWQNKPESVRCADLQSWLAPLLPLHEGLSMALRLLRESGRRADIAAEQGGYQQMLAGKIYHLLRVWVDPSLGVFPEISANKYMVWIRFSTQDGEVKPQQVSRDVAFQMSLCSS
What is the function of this protein?
Cell division factor that enhances FtsZ-ring assembly.  Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
What are the official names of this protein?
Cell division protein ZapD, Z ring-associated protein D.
What is the protein family that this protein belongs to?
Belongs to the ZapD family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to mid-cell in an FtsZ-dependent manner.
Protein: DUSA_PSEPK
Sequence: MSLETASTPHTTRPEPSRRFSVAPMMDWTDRHCRFFLRLLSRQTLLYTEMVTTGALLHNDAHRFLRHDASEHPLALQLGGSVPADLAACARLAEEAGYDEVNLNVGCPSDRVQNNMIGACLMAHPALVADCVKAMRDAVSTPVTVKHRIGINGRDSYAELSDFVGQVREAGCRSFTVHARIAILEGLSPKENREIPPLRYDIAAQLKRDFPDLEIVLNGGIKTLDECQAHLETFDGVMLGREAYHNPYLLAEVDQQLFGSDAPVVSRSEALAQLRPYIVAHMESGGAMHHVTRHILGLAQGFKGARRFRQLLSADIHKAAEPLAVFDQAVELLQGR
What is the function of this protein?
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.  Specifically modifies U20 and U20a in tRNAs.
What are the official names of this protein?
tRNA-dihydrouridine(20/20a) synthase, U20-specific dihydrouridine synthase, U20-specific Dus, tRNA-dihydrouridine synthase A.
What is the protein family that this protein belongs to?
Belongs to the Dus family. DusA subfamily.
Protein: CYB_MOUSE
Sequence: MTNMRKTHPLFKIINHSFIDLPAPSNISSWWNFGSLLGVCLMVQIITGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGLYYGSYTFMETWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAIVHLLFLHETGSNNPTGLNSDADKIPFHPYYTIKDILGILIMFLILMTLVLFFPDMLGDPDNYMPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSILILALMPFLHTSKQRSLMFRPITQILYWILVANLLILTWIGGQPVEHPFIIIGQLASISYFSIILILMPISGIIEDKMLKLYP
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NU2M_RHIUN
Sequence: MNPIVFSTILTTAIMGTVIVMMSSHWLMVWIGFEMNLLAIIPILMKKFNPRAMEASTKYFLTQATASMLLMSAIIINLMHSGQWTITKMFNPTASAIMTSALIMKLGLSPFHFWVPEVTQGISLMSGLILLTWQKLAPMSILYQIAPSINLDMLMTSALLSILVGGWGGLNQTQLRKIMAYSSIAHMGWMTAILTYNPTMTMLNMLIYIMMTLTTFMLLMLNSSTTTLSLSHTWNKTPLITSLILIIMLSLGGLPPLSGFIPKWMIIQELTKNNSIILPTSMAIMALLNLYFYLRLTYSTSLTMFPSTNNMKMKWQFENSKQMSLLPTLIIMSTLLLPLMPTMSILN
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RECA4_ARATH
Sequence: MYLSRAVSPRNVPVFSTGSFALDVALGVGGLPKGRLVEIYGPEASGKTALALHMLSMLLIRSLAKAIGVNTENLLLSQPDCGKQALSLVDTLIQSGSVDVIVVDSVAALVPKGELDGEMGDAHMAIQARLMSQALRKFSHSLLLSQTLLIFINQVRERFGGPTEVTSGGNALKFYAPMRLDIKRIGLIKKGEEFFRMTKCLCLNACAHNGKSSLREDSEEQARSAI
What is the function of this protein?
Involved in recombination ability and DNA strand transfer activity.
What are the official names of this protein?
Putative DNA repair protein recA homolog 4, Recombinase A homolog 4.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCFP_SALPC
Sequence: MIIYLHGFDSNSPGNHEKVLQLQFIDPDVRLVSYSTRHPKHDMQHLLKEVDKMLQLNVDERPLICGVGLGGYWAERIGFLCDIRQVVFNPNLFPYENMEGKIDRPEEYADIATKCVTNFREKNRDRCLVILSRHDEALDSQRSAQALHPYYEIVWDEEQTHKFKNISPHLQRIKAFKTLG
What are the official names of this protein?
UPF0227 protein YcfP.
What is the protein family that this protein belongs to?
Belongs to the UPF0227 family.
Protein: Y1024_STRP3
Sequence: MVSPRKGKRIRMLKKNDIIQVAISDLSHEGAGVAKHDGFVFFVDNALPEEVIDMRVLKVNKNSGFGKVEAYHYLSPARNADVNLTYLRTGIADLGHLTYEDQLTFKKKQVQDSLYKIAGISDVTVESTIGMTEPLAYRNKAQVPVRRVNGQLETGFFRKHSHDLIPISDYYIQDKEIDRLINFTRDLLRRFDIKPYDETEQTGLLRNIVVRRGHYSGEMMLVLVTTRPKVFRVDQVIEKIVEAFPAVVSIIQNINDKNTNAIFGKDFKTLYGKDTITDSMLGNNYAISAQSFYQVNTVMAEKLYQTAIAFSDLSKDDIVIDAYSGIGTIGLSFAKTVKAVYGVEVIEAAVRDAQHNAALNGITNAYFVADTAEHAMATWAKDGIKPSVILVDPPRKGLTESFIQASVAMGPQKITYVSCNPATMARDIKRYQELGYKLAKVQPVDLFPQTHHVECVVLLIKE
What are the official names of this protein?
Uncharacterized RNA methyltransferase SpyM3_1024.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
Protein: PP208_ARATH
Sequence: MRYQWRSLLFRSYRSSPRPFLSHHSRFQVISNSTRSFSSFLHERFGVQQRQCLFALRSPLASSVSRRFSSESAIEEKLPAETVVIDVFSRLNGKDEITKELDSNDVVISHELALRVLRELESSPDVAGRFFKWGLEAYPQKLSSKSYNTMLRIFGVNGLVDEFWRLVDDMKKKGHGVSANVRDRVGDKFKKDGLENDLERLKELFASGSMDNSVDKVCNRVCKIVMKEVWGADVEKQLRDLKLEFKSDVVKMVLEKLDVDPRKALLFFRWIDESGSFKHDEKTYNAMARVLGKEKFLDRFQHMIEEIRSAGYEMEMETYVRVSARFCQTKMIKEAVELFEFAMAGSISNTPTPHCCSLLLKKIVTAKKLDMDLFTRTLKAYTGNGNVVPDVMLQHVLKSLRSVDRFGQSNEVLKAMNEGGYVPSGDLQSVIASGLSRKGKKDEANELVNFMEASGNHLDDKAMASLVEGHCDAKDLEEASECFKKMIGKEGVSYAGYAFEKLVLAYCNSFQARDVYKLFSELVKQNQLKPWHSTYKIMVRNLLMKKVARDGGFEEALSLLPMMRNHGFPPFVDPFMDYLSNSGTSAEAFAFLKAVTSKKFPSNSMVLRVFEAMLKSARHSEAQDLLSMSPSYIRRNAEVLELFNTMKPEKCSLEKPLPAPAQIEA
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At3g02490, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ACP_RICRO
Sequence: MEFKIMSTTDKIEQKVIEMVAEKLNKDKSIITTDSRFIEDLKADSLDTVELMMAIEVEYGIDIPDDEATKIKTVSDVIQYIKERQS
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_SALHS
Sequence: MERYENLFAQLNDRREGAFVPFVTLGDPGIEQSLKIIDTLIDAGADALELGVPFSDPLADGPTIQNANLRAFAAGVTPAQCFEMLALIREKHPTIPIGLLMYANLVFNNGIDAFYARCEQVGVDSVLVADVPVEESAPFRQAALRHNIAPIFICPPNADDDLLRQVASYGRGYTYLLSRSGVTGAENRGALPLHHLIEKLKEYHAAPALQGFGISSPEQVSAAVRAGAAGAISGSAIVKIIEKNLASPEQMLAELRSFVSAMKAASRA
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: A1L3_LOXSA
Sequence: WIMGHMVNAIYQIDEFVNLGANSIETDVSFDDSANPEYTYHGVPCDCRRWCKKWEYFNNFLKALRKATTPGDSKYHEKLVLVVFDLKTNSLYDHQAYDAGKKLAKNLLQHYWNNGNNGGRAYIVLSIPNLSHYKLITGFKETLKNEGHPELMEKVGFDFSGNDNIDQVAKAYKKAGVTGRVWQSDGITNCIASFIRGLDRAKEAVANRDSSNGFINKVYYWTVDKRATTREALDAEVDGIMTNDPDVIADVLNESAYKAKFRIATYDDNPWETFKK
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LsaSicTox-alphaIB2iii, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS6_BURL3
Sequence: MRHYEIVFIVHPDQSEQVPAMIERYKTTITSHGGQIHRVEDWGRRQLAYMIEKLAKAHYVCMNIECDQTTLDELEHAFKFNDAVLRHLIVKMKKAETGPSPMMKEVQREEAKKAAAAQPTEAQA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: Y107_METJA
Sequence: MREIMKILIITGKLAERKVKDAVKKYDFIDVHVANISVAAFLTPNLIIKEIKKLENKLGKKLKDIYDFVLVTGLIRHDLKNVEEETGIKCFKSTREASDIPILIENLDKIKLSTKEYADLQLLEIIRKKCEEEIKKAEEQELGEGDIKIGKLKVGDKFPMRVLGEIVHAPWLKEKELEEKIIYYLESGADMIDLGMVSNENNADKIKDMLKIARDLTDNPISVDTLNTKELIEAINLGADMILSVDAGNLDELIPYLKDSETAVVVLPTNYKTNYVPETIEGKIKSLEENIKKLIDAGIEKIVADPILEPINNAGCSFIESVIACREFKKRNKLPLFFGVGNVTELFDADSNGVNALLAAIGAEIGANILFTPEASAKCKFSIKELKIASKMMFLAKKRNSLPKDIGYNLINYKDKRFEEEITFNSYNIPIIKAEEDERQILDEGSFKIEIDRKNKEIVAIYFNKRREPVLIIRGKKPKEIYETAIRLNLIKKLDHASYFGRELAKAEIALRIGKKYNQDFDLFL
What is the function of this protein?
Unknown.  Does not possess dihydropteroate synthase (DHPS) activity since it does not catalyze the condensation of 6-hydroxymethyl-7,8-dihydropterin pyrophosphate (DHPP) and 4-aminobenzoate to form 7,8-dihydropteroate.
What are the official names of this protein?
Uncharacterized protein MJ0107.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: I17RE_HUMAN
Sequence: MGSSRLAALLLPLLLIVIDLSDSAGIGFRHLPHWNTRCPLASHTDDSFTGSSAYIPCRTWWALFSTKPWCVRVWHCSRCLCQHLLSGGSGLQRGLFHLLVQKSKKSSTFKFYRRHKMPAPAQRKLLPRRHLSEKSHHISIPSPDISHKGLRSKRTQPSDPETWESLPRLDSQRHGGPEFSFDLLPEARAIRVTISSGPEVSVRLCHQWALECEELSSPYDVQKIVSGGHTVELPYEFLLPCLCIEASYLQEDTVRRKKCPFQSWPEAYGSDFWKSVHFTDYSQHTQMVMALTLRCPLKLEAALCQRHDWHTLCKDLPNATARESDGWYVLEKVDLHPQLCFKFSFGNSSHVECPHQTGSLTSWNVSMDTQAQQLILHFSSRMHATFSAAWSLPGLGQDTLVPPVYTVSQARGSSPVSLDLIIPFLRPGCCVLVWRSDVQFAWKHLLCPDVSYRHLGLLILALLALLTLLGVVLALTCRRPQSGPGPARPVLLLHAADSEAQRRLVGALAELLRAALGGGRDVIVDLWEGRHVARVGPLPWLWAARTRVAREQGTVLLLWSGADLRPVSGPDPRAAPLLALLHAAPRPLLLLAYFSRLCAKGDIPPPLRALPRYRLLRDLPRLLRALDARPFAEATSWGRLGARQRRQSRLELCSRLEREAARLADLG
What is the function of this protein?
Specific functional receptor for IL17C.  May be signaling through the NF-kappa-B and MAPK pathways.  May require TRAF3IP2 /ACT1 for signaling.  May be a crucial regulator in innate immunity to bacterial pathogens.  Isoform 2 and isoform 4 may be either cytoplasmic inactive or dominant active forms.  Isoform 3 and isoform 5 may act as soluble decoy receptors.
What are the official names of this protein?
Interleukin-17 receptor E, IL-17 receptor E, IL-17RE.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Single- pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. SUBCELLULAR LOCATION: [Isoform 3]: Secreted. SUBCELLULAR LOCATION: [Isoform 4]: Cytoplasm. SUBCELLULAR LOCATION: [Isoform 5]: Secreted.
Protein: DCD_ACIF5
Sequence: MSIKSDRWIRHMAEEHGMIEPFSPRQVRHVEGNSIISYGLSSYGYDIRCAGEFKVFTNVRSVIVDPKNFSEHSFVDFTGDTCIIPPNSFALARTLEYFRIPRNVLTICLGKSTYARCGIIVNVTPFEPEWEGYVTLEFSNTTPLPAKIYANEGVAQVLFLESDEVCEVSYADRGGKYQGQSGVTLPKA
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: PPC89_SCHPO
Sequence: MPSQFNDNFVATDDDVGTMARVGMALDRELNGDSFQDNLNFQPRSGKREDFEPFFQDTPNTKSLSKHFHDFTMNASLETLPSVEKPRGRNMNAFEETSWNRFRKNGSLFPLSSPPISEPDLRPQALNETPDYRNRFLGAFKKQGVLDDHGNLKLDASPSFLKKPAEYTPLANRQNQNLAFDSPTEALPPKPTTPWRRNGFRSKTTPNLNSGKETPSSYKASARLMEQLGLNHSEPSVDFNNQTSYRLPNLTNLSSLIRDDTIDENGNAKEHDRLPELNTIPVASTDEQLFNAHQLLEKKFEILKRERNECNAKIDELQDKLELLTDAYNREKRRARSLEERMSKEMLTKLGESNVDDGMAASRYDTVKREKERLSEHLKSLQEQYEHIQSVYKNVLLDRESYIMRLGNKISENNELLNENRVLKEKLQTYLDKKESNVTSKIKSTAENSSKPLSMNEADERKDGLNNLLFENKSGANTKEMSNGTETAKENCSPQQDSTSPTSGYQDLVKELAKEIEMRKSLELKLKLSQSNKAGPVKHRKRRPKSKRRITGKVVFDSPNVASGVESDEGSEEISLDSEYSDILSDDGDFEKEKQATLPRRRSSSSMKGNKLAEDSYLNEAGFDWNQGTFHNGSEFGTTGVPDEPNEEELPKHVLKQVEHIINESAAHGVGKCNACHARQEDLIRGEQKVSHSNCLYADQTLRPSQPPSEALKTVVNQLTNELMELKKRYEKLSDRYNSLTPGYHKHKRQEIKNKLIKLIECMESKSDQIYLLYDVNVGKDFS
What is the function of this protein?
Has a role in meiosis.
What are the official names of this protein?
Spindle pole body protein ppc89, Meiotically up-regulated gene 127 protein.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body.
Protein: APT_METRJ
Sequence: MEARRHVALKESVRSIPDYPKPGIIFRDITTLLSDPRAFRRAVDALVHPYAGGQIHQVAGIEARGFILGGAIAHQLSCGFVPIRKKGKLPHKTVSMAYALEYGTDEIEIHVDAVRPGDKVLLVDDLIATGGTAIAAVNLLQKIGAEIVAACFVIDLPEIGGAQRLRDLGVEVRTLMQFEGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: JANB_DROER
Sequence: MKMFQSLSLLPRIVSPFRKCYSTDLISLVGVPRVKITKGQNRYLLVNIHTHGFTKYGRVIVRGADVENHLTIFDSILEELEPQGICAKILGGGRILNETDSKKMKIYGTSRTFGSADHTRTRNILQSWTTYKDFKITVKN
What is the function of this protein?
JanA and janB regulate somatic sex differentiation.
What are the official names of this protein?
Sex-regulated protein janus-B.
What is the protein family that this protein belongs to?
Belongs to the janus family.
Protein: ALR_SHEPW
Sequence: MKPFPRAEISRKALKHNLARLHELAPSSKVMAVVKANGYGHGLLNVAQCLDNADGFGLARLEEALALRTGGVTAKLLLLEGFFRIGDLTTLVEHDIETVVHHESQLEMLESINLTKPVTVWLKVDSGMHRLGFSPAQFDATYQRLMANDNVAKPIHLMTHFACADEPSNPSTAEQQRVFDTLIKGLPGDRTLANSAGALFWQQSQADWIRPGIALYGVSPVFGDLGAKHGLMPAMDLVSQLIAIREHKAGESAGYGSYWTAEKDTNLGVVAIGYGDGYPRNAPLGTPVLVNGRIVPIVGRVSMDMLTVDLGIDANDKVGDLAVLWGKELPVEEVAEHIGTIAYELVTKLTPRVAVCLD
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: RDH10_BOVIN
Sequence: MNIVVEFFVVTFKVLWAFVLAAARWLVRPKEKSVAGQVCLITGAGSGLGRLFALEFARRRALLVLWDINTQSNEETAGMVRHIYRDLEAADAAALQAGNGEEEILPHCNLQVFTYTCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFWTTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDYCASKFGVVGFHESLSHELKAAEKDGIKTTLVCPYLVDTGMFRGCRIRKEIEPFLPPLKPDYCVKQAMKAILTDQPMICTPRLMYIVTFMKSILPFEAVVCMYRFLGADKCMYPFIAQRKQATNNNEAKNGI
What is the function of this protein?
Retinol dehydrogenase with a clear preference for NADP.  Converts all-trans-retinol to all-trans-retinal.  Has no detectable activity towards 11-cis-retinol, 9-cis-retinol and 13-cis-retinol (By similarity).
What are the official names of this protein?
Retinol dehydrogenase 10.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Microsome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: AAR2_PONAB
Sequence: MAAMQMDPELAKRLFFEGATVVILNMPRGTEFGIDYNSWEVGPKFRGVKTIPPGIHFLHYSSVDKANPKEVGPRMGFFLSLHQRGLTVLRWSTLREEVDLSPAPESEVEAMRANLQELDQFLGPYPYATLKKWISLTNFISEATVEKLQPENRQICAFSDVLPVLSMKHTKDRMGQNLPRCGTECKSYQEGLARLPEMKPRAGTEIRFSELPTQMFPEGATPAEITKHSMDLSYALETVLNKQFPSSPQDVLGELQFAFVCFLLGNVYEAFEHWKRLLNLLCRSEAAMMKHHTLYINLISILYHQLGEIPADFFVDIVSQDNFLTSTLQVFFSSACSIAVDATLRKKAEKFQAHLTKKFRWDFAAEPEDCAPVVVELPEGIEMG
What is the function of this protein?
Component of the U5 snRNP complex that is required for spliceosome assembly and for pre-mRNA splicing.
What are the official names of this protein?
Protein AAR2 homolog, AAR2 splicing factor homolog.
What is the protein family that this protein belongs to?
Belongs to the AAR2 family.
Protein: CSPLC_ORYSI
Sequence: MGSIGNGRNGSEVGIQIPAMGNKEVLERPAIPRWPRLGVVMVATRAVALVMAVLSMALMISAKQRGSLKIFGIEIPLYANWSFSDSLEYLVGMSAVSAAYCLAQLLLTAHKAVKNAPVVQSRNYAWLLFTGDQIFAYAMMSAGSAAAAVANLNRTGIRHTALPNFCKPLPRFCDLSAASIACAFLSCIFLAASAVIDVIWLSNM
What are the official names of this protein?
CASP-like protein 3A1, OsCASPL3A1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.