PharMolix/UniProtQA huggingface dataset:
Protein: SYK_SULAC
Sequence: MFHIIDLALKWDERRVKIVDELKSKGINPYPHKYDITHTIIDIKKMERSDKPTDAFAFDISTAGRVANIRRHGKISFVDIFDEGERLQLQLRVNELGDRYDKFFEIVDRGDILGVKGDLLYTIKGELTLRIKDYVLLSKSLIEPPDWSKLSPEFRYAHRYVDFLYNDLARRNMEIRYSTIRRIREFLYSKGFMEVETPILQPVYGGALAKPFMSHVNYLNENWYLRISLELYLKRYIVGGFNKVFEIGKVFRNEDIDVTHNPEFTLLELYWAYADYNDIMRLTEEMLQDVVKNINNDSKIKYSIGGKEYTIEFSQFRKITMIDSLTEVLGKDVDKMSDEELKSLMDKNGLKPRGNMYIRGLMIEKLFDKLVTPTLIQPTFVLDYPVETTPLCKPHRSKQGLVERFELYVAGMELANAYTELNDPIIQDMLFKQEQEMFKRGDEEAHPYDVDFVRALSYGMPPTGGLGIGIDRLIMLLTNNMSIKEIIPYPMLSAKVIQED
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYAY_ECOK1
Sequence: MNDSEFHRLADQLWLTIEEHLDDWDGDSDIDCEINGGVLTITFENGSKIIINRQEPLHQVWLATKQGGYHFDLKGDEWICDRSGETFWDLLEQAATQQAGETVSFR
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: GSA_LEGPA
Sequence: MSRSSDLFHKAQTIIPGGVNSPVRAFKGVGGEPVFFKSGKGAYLTDVDDKQYIDYVGSWGPLILGHCHPKVIEAVDNVLHSGMSFGAPTELEIQLAEKIASLMPSIEKIRMVNSGTEATMTAIRLARGFTNKNKFIKFNGCYHGHSDSLLVKAGSGLLTLGIPSTPGIPKSITEHTLTADFNNLEQVAQLFEKYPNDIATVILEPVPGNMGFILPKIEFLKGLRELCDQYNALLIFDEVMTGFRVGLHGAQGLFGIKPDITTLGKIIGGGMPVGALGGKREIMSFLAPEGPVYQAGTLSGNPLAMAAGLATLKEIEKINFFEDLSNTTNKLTEALADAAENANIPFFAASLGGMFGFCFTDKNSVENYFDVASSDEVLFKKFFHAMLAQGVYFAPSMYEAGFVSSMHGDLEIQKTYDAAELVLNQLSA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPH_CRUWA
Sequence: MNPLVSAASVIAAGLAVGLASIGPGVGQGTAAGQAVEGIARQPEAEGKIRGTLLLSLAFMEALTIYGLVVALALLFANPFV
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, chloroplastic, ATP synthase F(0) sector subunit c, ATPase subunit III, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: COAX_THEAB
Sequence: MLLLFDVGNTHTTIALTKDGKSFDIKRVSTHSIQTEDELYVFLKMFYRNDFKDIVVSSVVPNINYIFEFFAEKYLNKKAIFVSAKEYNEIIWNVNTPEEIGADRVVDVIAASRDYGKDAIVVDFGTAITIEVLKENRYEGGVIIPGFNMMVNALFKGTAKLPKVELKPSDTFVGKDTGSNIRIGVINTILGGIDYTIERIKSDYDLKSAPIIYTGGQSKLIREYLKKDIIYDLELGLRGIYYFYENIAC
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_RHILW
Sequence: MARIAGVNIPTAKRVVIALTYIHGIGPKFAQEIVEKVGIPAERRVHQLTDAEVLQIREAIDRDYQVEGDLRRDTAMNIKRLMDLGCYRGLRHRRGLPVRGQRTHTNARTRKGPAKAIAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: LEUC_VARPS
Sequence: MARTLYDKIWDEHVVHTEEDGTAILYIDRHLVHEVTSPQAFEGLREAGRKLWRISSVVATADHNTPTTGWERGYEGIADPTSKEQVTTLDKNIAEFGAAAFFPFLSKRQGIVHVIGPESGATLPGMTVVCGDSHTSTHGAFGALAHGIGTSEVEHVMATQTLLGKKAKNMLVKVEGKLPFGCTAKDIVLAIIGKIGTAGGTGYTIEFAGSAIRDLSMEGRMTVCNMAIEAGARAGLVAVDEKTIGYIKGRPLAPTGVEWDQAVAYWRTLQSDPDAAFDAVVELDATQIQPQVTWGTSPEMVVDINGRVPDPDKEKDASKRSAIERALVYMGLEPNKAMNDIFIDKVFIGSCTNSRIEDMREAAAVVKKLGQKVAKNVKLAMVVPGSGVVKEQAEREGLDVIFKAAGFEWREPGCSMCLAMNADRLEPGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAAVHGHFVDVRTFA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: Y1381_STRPC
Sequence: MDPKKIARINELAKKKKTVGLTGPEKVEQAKLREEYIEGYRRSVRHHIEGIKLVDEEGNDVTPEKLRQVQREKGLHGRSLDDPKS
What are the official names of this protein?
UPF0291 protein MGAS9429_Spy1381.
What is the protein family that this protein belongs to?
Belongs to the UPF0291 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_CLOBA
Sequence: MARIAGVDLPREKRVEIALTYIYGIGLSTSQKILSTTGISPDARVKDLSEDEVNEIRTYINKNLMVEGDLRRDVALNIKRLVEIGSYRGIRHRRGLPVRGQKTKTNARTRKGPKKTMANKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: MCAT_HUMAN
Sequence: MADQPKPISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREGITGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQKHPEDVLSYPQLFAAGMLSGVFTTGIMTPGERIKCLLQIQASSGESKYTGTLDCAKKLYQEFGIRGIYKGTVLTLMRDVPASGMYFMTYEWLKNIFTPEGKRVSELSAPRILVAGGIAGIFNWAVAIPPDVLKSRFQTAPPGKYPNGFRDVLRELIRDEGVTSLYKGFNAVMIRAFPANAACFLGFEVAMKFLNWATPNL
What is the function of this protein?
Mediates the electroneutral exchange of acylcarnitines (O-acyl-(R)-carnitine or L-acylcarnitine) of different acyl chain lengths (ranging from O-acetyl-(R)-carnitine to long-chain O-acyl-(R)-carnitines) with free carnitine ((R)-carnitine or L-carnitine) across the mitochondrial inner membrane, via a ping-pong mechanism (PubMed:12892634, PubMed:18307102) (Probable).  Key player in the mitochondrial oxidation pathway, it translocates the fatty acids in the form of acylcarnitines into the mitochondrial matrix, where the carnitine palmitoyltransferase 2 (CPT-2) activates them to undergo fatty acid beta-oxidation (Probable).  Catalyzes the unidirectional transport (uniport) of carnitine at lower rates than the antiport (exchange) (PubMed:18307102).
What are the official names of this protein?
Mitochondrial carnitine/acylcarnitine carrier protein, Carnitine/acylcarnitine translocase, CAC, CACT, Solute carrier family 25 member 20.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
Protein: NUOB_GEODF
Sequence: MGVEQPLGDNIVTASLDGLVNWARKTSIWPMTFGLACCAIEMMATGAAKHDLDRFGIIFRASPRQADCIIIAGTVTKKMLPVIKTVYEQMPEPKWVIAMGACACSGGVFDTYSVVQGIDEALPVDVYVPGCPPRPEALLYGIMKLQDKIGKERNSFGSAIGLGDRLEPAA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HISX_PICTO
Sequence: MDIYEYVSNIISDVRINGIDALKRYSEAFDNYSGGFTVTDDEIEDADKSIKPGEKDAIKNIYERIYEYHKNQFEGQKINIKNGSIYGIIYRPIDRIGLYVPGKRALPSTLMMLGIPARIAGVKSIVLCTAPENGNVNKYTLYIARLLGIREIYKIGGVQAIAAMAYGISMKPVDKIFGPGNKYVNEAKRQVFGITGIDGLYGPSEICLIADDSANINYIKNDLLSQLEHGEASSAYLITNSLRIYNEVKLENVKKYYKETVEESIELANEIAPEHLELLVNDPLKYLNIIRNAGAVYMGEYGPVPAGDYFLGVNHVLPTGSSARFSSVLTVYDFMKRISVAMPSKYDFLSAVDSGLKLASIENMKMHYKSMEARI
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: RNZ_PARMW
Sequence: MQVTFLGTSSGVPTRARNVSAVALRLPQRSEMWLFDCGEGTQHQFLRSDLRLSQLRRVFVTHMHGDHVFGLPGLLASLGLSGSCQDGVDLYGPDPLESFLKGALNTSSTRIGYPLQVHRSRPAAEQGTLLFEDDELTVRCTPLTHRVPAYAYRVDQKPLAGRFDIDKARSLGIPPGPVYAQLKRGESVTLEDGRVIDGTTLCGPERPGVSVMICTDTVFCDAAVELARGVDLLIHESTFAHAEAEMAFQKQHSTSTMAAQTAAEAGVGQLAITHLSPRYVPGNPVSPDDLLKEAQAIFPNTVLAKDFLSLDVKPCCNSS
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: TATD_ENTLS
Sequence: MFDIGVNLTSPQFARDHDAVVARAFAAGLSGMLLTGTSLHESEQALALAQRHARCWSTAGVHPHDSSRWTRETEQRIRTLAQAPEVVAIGECGLDFNRNFSTPQAQEAAFSAQLALAAECGMPVFLHCRDAHERFMALLTPWLDKLPGAVLHCFTGTRDELQDCLRHGLYIGITGWVCDERRGLALRDMLPLIPANRLMVETDAPYLLPRDMTPKPGSRRNEPAYLAHIMARIAHWRGEDAQWLSGETDNNVRTLFGVAM
What is the function of this protein?
3'-5' exonuclease that prefers single-stranded DNA and RNA.  May play a role in the H(2)O(2)-induced DNA damage repair.
What are the official names of this protein?
3'-5' ssDNA/RNA exonuclease TatD, DNase TatD.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. TatD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_XANP2
Sequence: MRHGKVHRKFNRTWEHRKAMFSNLAGALITHEQIVTTLPKAKDLRPVVEKLVTLARRGDLHARRQAIAELKDVTIVKKLFDVLAPRYKERPGGYTRIIKAGFRYGDNTAMAVIEFVDRDVDAKGAADHARTAAAAEAEAA
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: MRAY_RICAH
Sequence: MLYNLLLPHIHNSHIANLFHYITFRSGLAIIITLSLSFIMGPILIKFLRSLQKNGQPIRSDGPESHQTKAGTPTMGGIMIILSSGLSTLLLADLTNQYIWITLFGFISFGIIGFMDDYAKVTKNNHYGVRGKSKLVLQGIISLIICVLLEYLDKNPSHLLNVPFFKNLNLDLGYFYIVFAIFVIVGSSNAVNLTDGLDGLATVPIAFTAGSFALISYLVGNLIYSHYLQLTYIPNTGELTVLCAGLVGSCLGFLWFNAQPAEVFMGDTGSLSLGGVLGIISVITKHEIVLAIVGGLFVIETASVILQVYYFKATQGKRIFKMAPLHHHFEKHGWAESKVVIRFWIISVIFALIGLSSLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PLIN5_HUMAN
Sequence: MSEEEAAQIPRSSVWEQDQQNVVQRVVALPLVRATCTAVCDVYSAAKDRHPLLGSACRLAENCVCGLTTRALDHAQPLLEHLQPQLATMNSLACRGLDKLEEKLPFLQQPSETVVTSAKDVVASSVTGVVDLARRGRRWSVELKRSVSHAVDVVLEKSEELVDHFLPMTEEELAALAAEAEGPEVGSVEDQRRQQGYFVRLGSLSARIRHLAYEHSVGKLRQSKHRAQDTLAQLQETLELIDHMQCGVTPTAPACPGKVHELWGEWGQRPPESRRRSQAELETLVLSRSLTQELQGTVEALESSVRGLPAGAQEKVAEVRRSVDALQTAFADARCFRDVPAAALAEGRGRVAHAHACVDELLELVVQAVPLPWLVGPFAPILVERPEPLPDLADLVDEVIGGPDPRWAHLDWPAQQRAWEAEHRDGSGNGDGDRMGVAGDICEQEPETPSCPVKHTLMPELDF
What is the function of this protein?
Lipid droplet-associated protein that maintains the balance between lipogenesis and lipolysis and also regulates fatty acid oxidation in oxidative tissues.  Recruits mitochondria to the surface of lipid droplets and is involved in lipid droplet homeostasis by regulating both the storage of fatty acids in the form of triglycerides and the release of fatty acids for mitochondrial fatty acid oxidation.  In lipid droplet triacylglycerol hydrolysis, plays a role as a scaffolding protein for three major key lipolytic players: ABHD5, PNPLA2 and LIPE.  Reduces the triacylglycerol hydrolase activity of PNPLA2 by recruiting and sequestering PNPLA2 to lipid droplets.  Phosphorylation by PKA enables lipolysis probably by promoting release of ABHD5 from the perilipin scaffold and by facilitating interaction of ABHD5 with PNPLA2.  Also increases lipolysis through interaction with LIPE and upon PKA-mediated phosphorylation of LIPE (By similarity).
What are the official names of this protein?
Perilipin-5, Lipid storage droplet protein 5.
What is the protein family that this protein belongs to?
Belongs to the perilipin family.
What are the subcellular locations of this protein?
Lipid droplet. Cytoplasm. Mitochondrion. Note=Lipid droplet surface-associated. Exchanges between lipid droplets and the cytoplasm.
Protein: LEC_MYTTR
Sequence: MTTFLIKHKASGKYFHPKGGTSNPPNGTNLVLHSDIHERMYFQFEVVNERWRYIKHVASEKIVHPFGGKADPLNGTNMVLHQDRHDRALFAMDFFNDNIRHKGGKYIHPKGGSKNPSNGNLTVMHGDEHGAMEFIFVSPKNKDKRVLVYA
What is the function of this protein?
D-galactose-binding lectin (PubMed:26802895, Ref. 2).  Binds both alpha and beta anomer of galactose (Gal).  Binds strongly to branched beta-Gal-terminated glycans and weakly to unbranched glycans with alpha-Gal on the end of chains (PubMed:31905927).  Has strong affinity for both Gal and GalNAc.  Binds glycoproteins containing mucin-type chains.  Has hemagglutinating activity towards human group A erythrocytes (Ref. 2).  Has hemagglutinating activity towards rabbit erythrocytes (PubMed:30292806).  Agglutinates V. proteolyticus bacteria.  Binds strongly to fungi including species from genera Aspergillus, Alternaria, Fusarium and Haematonectria, and to a lesser extent to fungi from genera Trichoderma.  Decreases conidia germination and hyphal growth of fungi (PubMed:26802895).  At high concentration, stimulates secretion of cytokines TNF-alpha and IFN-gamma from human peripheral blood cells, and at low concentration reduces hyperexpression of cytokine IL-10 in these cells, indicative of immunomodulatory capability.  However, has no effect on IL-4 production (Ref. 2).  Recognizes pathogen-associated molecular patterns (PAMPs) and binds to peptidoglycan from S. aureus, but has only little binding to beta-1,3-glucan from E. gracilis and lipopolysaccharide (LPS) from E. coli (PubMed:31905927).  May be involved in innate immunity acting as an antibacterial or antifungal agent recognizing carbohydrate ligands on the surface of pathogens (PubMed:26802895, PubMed:31905927).
What are the official names of this protein?
D-galactose-binding lectin, GalNAc/Gal-specific lectin, MTL.
Protein: UPP_CLOAB
Sequence: MSKVTQISHPLILHKLAFMRDKKTGSKDFREMVEEVAMLMAYEVTREMQLETVEIETPICITKCKMLAGKKVAIVPILRAGLGMVNGVLKLIPAAKVGHIGLYRDEKTLKPVEYFCKLPQDIEERDIIVTDPMLATGGSAIDAITLLKKRGAKYIRLMCLIGAPEGIAAVQEAHPDVDIYLASIDEKLDENGYIVPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: GCY9_CAEEL
Sequence: MRLYLFFISSLLLAESRRSISKISHDEINQHVKTTLSSEGIVRIGHLHPTNPIIAHEPDVLKMCADDLKMRNILPQNYTLTVFTMESCNKYSGVEHAAFLHYLKNASVYFGPGCNNEMLVIGRLAPRWNVPIIAHMSGDDALSDRVQFPTLGSVALTSASEMAKATVTYLNLNNWDQIGIVRPSVGYERLSVYSLQHQIKKRDINLNVILDIEPFSSPEEIISTGKLTTLKSMARIIVVELGMDIHSVTNFMLAIHRSEIKNEEFVFVIPWLAHQNDHYPWEAANVDKQEVKLAFENTIIITAHGYDKKFFDDFQMKFSAVTGVLANHYATLSYMSLYDALFLYGLALRDAFEDGGGYNVHMNGSLIWSRMTNRQFIGMTGQVLMNNKAIRVPSYATYHAINGTLKIVVELEAKNNDRGQCEKNEEMCSEHVAHETIQYYWPSDSGKLPPAVPKCGFTGAECDYRPYFIGASLLAFILTVGPLSYFIYLKQKERLLYDMTWRIPRESIKMLEGKSKSEHSLASKSQSSGSFSGSMNSKQNGLIAAKQAVSNGVKLAIKRYQQVRNITFPKSELRLLKELKICENDNLNKFYGISFNQQNEFIVMWVLCSRGSLEDILFNDELKLGRNFQVSFAKDVVKGLNFLHTSPLLHHGMLCLQNCLVDSNWTVKLTNFATEAVIFEKLDHNELRPFINTDSESADDVSDPTKDFARKKYLQQAPEIIREIVTTKTIPEGSQSADIYALGMVLYQILFRVEPFHERNKSINKLMETLAMANDDDQLIRPTFPSSNTGEGYNLQLLSCIEACWLEIPEMRPPIKKVRTMVNANLKSTGKGSLVDQMMKMMEEYTANLENMVRDRTALLEEAQKQADRLLNSMLPKSIAEDLKIGKPVLPQLYSCATVLFSDIRGFTRISSTSTPLQVVTFLNDMFSGFDAIIAKHDAYKVETIGDAYMIVSGVPTENGNSHAQNIADVALKMRAFICNFKLAHRPEELMMVRIGFHSGPVAAGVVGLAAPRYCLFGDTVNTASRMESTGVANKIQISEGAYNLLHCFFPQFQMVERGKIEVKGKGECLTYYLEGRTGKQ
What is the function of this protein?
Guanylate cyclase involved in the production of the second messenger cGMP (By similarity).  Involved in the sensing of CO2 levels and acidity by the BAG neurons.  May act as a direct receptor for CO2 and H+ (PubMed:21173231, PubMed:24240097).
What are the official names of this protein?
Receptor-type guanylate cyclase gcy-9.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell projection, cilium. Note=Localizes in cilium of sensory neurons.
Protein: RSMB_YERPB
Sequence: MKNTYNLRSIAAKAISQVLDQGQSLSAVLPELQKNISDKDRALLQELCFGTLRVLPQLEWCIQQLMARPMTGKQRVFHYLIMVGLYQLIYTRIPPHAALAETVEGATVLKRPQLKGLINGVLRQFQRQQVELLERAVNNDSHYLHPSWLLARIKQAYPAQWQQILDANNQRPPMWLRVNRLHHSRSEYLELLTQADINAEPHPIYRDAVRLITPCAVNHLPGFELGWVTVQDASAQGCVDLLDPQNGEQILDLCAAPGGKTTHILEAAPKAHVLAVDIDEQRLSRVKENLQRLQLQAVVRVGDGRAPDTWCGDQQFDRILLDAPCSATGVIRRHPDIKWLRRDRDISELAQLQSEIIEAIWPKLKHGGVLVYATCSILPEENQQQIAAFLQRHPEAQLTETGTTAAPGKQNLPHPEDGDGFFYAKIIKK
What is the function of this protein?
Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase B, 16S rRNA m5C967 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmB.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAA_BURO1
Sequence: MHDKILILDFGSQVTQLIARRVREAHVYCEIHPNDVSDDFVREFAPKAVILSGSHASTYEDHQLRAPQAVWDLGVPVLGICYGMQTMAVQLGGKVEWSDHREFGYAEMRAHGHTRLLDGIEDFTTAEGHGMLKVWMSHGDKVAELPPGFALMASTPSCPIAGMADEARGYYAVQFHPEVTHTVKGRQIIERFVLQIAGAKPDWIMKNHIEEAVAKIREQVGDEEVILGLSGGVDSSVAAALIHRAIGDQLTCVFVDHGLLRLNEGKMVLDMFEGRLHAKVVHVDASDQFLGHLAGVTDPEAKRKIIGREFVEVFQAEAKKLSKAKWLAQGTIYPDVVESGGTKTKKATTIKSHHNVGGLPETLGLKLLEPLRDLFKDEVRELGVALGLPPEMVYRHPFPGPGLGVRILGEVKREYAELLRRADAIFIEELRNTTATAQDAAAGLCGEADVGKSWYDLTSQAFAVFLPVKSVGVMGDGRTYDYVTSLRAVQTTDFMTAHWAHLPYALLGRASNRIINEVRGINRVVYDISGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: FABH_STRPF
Sequence: MIFSKISQVAHYVPQQLVTNNDLANIMDTSHEWIFSRTGIAERHISRDEMTSDLAIQVADQLLTQSGLKADAIDFIIVATISPDATMPSTAAKVQAAIAATSAFAFDMTAACSGFVFALAMADKLIASGAYQNGMVIGAETLSKLVNWQDRATAVLFGDGAGGVLLEASKDKHVLAETLHTDGARCQSLISGETSLSSPYSIGKKAIATIQMDGRAIFDFAIRDVSKSILTLMAQSDITKDDIDYCLLHQANRRILDKIARKIDVPREKFLENMMRYGNTSAASIPILLSEAVQKGQIRLDGTQKILLSGFGGGLTWGSLIVKI
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3918_ARATH
Sequence: MVESELSYEQIRLNRVEENKKRMGELNLNKLAQSLRVSSSSSSSSKPSPAKPRTMRIPVDFSEVRRSSRAKGPPPSYKEFGLEPLERRPRRSSRRRDLLNRVYASDDARMYAFDRAEKLQSSLDSEYASFTKPMLQSHVTGGFWLGLPLPFCKAHMPKRDVIMTLVDEEEEESQAKYLAQKNGLSGGWRGFAIDHQLVDGDAVVFHLIARTTFKVYIIRVNDDANNDSDGNEVNDDDSDGNEEDRDNDNESNEKQKETVSEGRQLRSSGKRKRRGRK
What are the official names of this protein?
B3 domain-containing protein At3g19184.
What are the subcellular locations of this protein?
Nucleus.
Protein: TUSB_SHIF8
Sequence: MLHTLHRSPWLTDFAALLRLLSEGDELLLLQDGVTAAVDGNRYLESLRNAPIKVYALNEDLIARGLTGQILNDIIPIDYTDFVRLTVKHSSQMAW
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
What are the official names of this protein?
Protein TusB, tRNA 2-thiouridine synthesizing protein B.
What is the protein family that this protein belongs to?
Belongs to the DsrH/TusB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CARB_MYCSK
Sequence: MPRRTDLRHVLVIGSGPILIGQAAEFDYSGTQACRVLRAEGLTVTLINSNPATIMTDPEYADYTYVEPITPDFVERVIAQQAERGNKIDALLATLGGQTALNTAVALSENGVLERYDVELIGADFDAIQRGEDRQRFKDIVTKVGGESAKSRVCFTMEEVRETVGELGLPVVVRPSFTMGGLGSGMAYSAEDVERMAGHGLASSPSANVLIEESIFGWKEYELELMRDRHDNVVVVCSIENFDPMGVHTGDSVTVAPAMTLTDREYQTMRDLGIAILREVGVATGGCNIQFAVNPKDGRLIVIEMNPRVSRSSALASKATGFPIAKIAAKLAIGYTLDEILNDITKETPACFEPTLDYVVVKAPRFAFEKFPGADATLTTTMKSVGEAMSLGRNFIEALGKVMRSLETGRAGFWTAPDPIATVDEVLENLRTPTDGRLYDIEFALRLGASVEQVAEASGVDPWFVDQIAGLVALRTELLDAPVLDGTLLRRAKNSGLSDRQIAALRPELAGEVGVRALRQRLGIHPVFKTVDTCAAEFEAKTPYHYSSYELDPAAESEVAPQAERPKVLILGSGPNRIGQGIEFDYSCVHAATTLSEAGFETVMINCNPETVSTDYDTADRLYFEPLTFEDVLEIYYAESASGAGGPGVAGVIVQLGGQTPLGLAERLEQAGVPIVGTSPKAIDLAEDRGAFGEVLRTAGLPAPRFGLATTFDQARRIAADIGYPVLVRPSYVLGGRGMEIVYDEQTLEGYITRATQLSPEHPVLVDRFLEDAIEIDVDALCDGTEVYIGGIMEHIEEAGIHSGDSACALPPVTLGRSDIESVRRATEAIAHGVGVVGLLNVQYALKDDVLYVLEANPRASRTVPFVSKATAVPLAKACARIMLGASIAQLREEGVLAATGDGATTARNAPVAVKEAVLPFHRFRKADGAQIDSLLGPEMKSTGEVMGIDHDFGSAFAKSQTAAYGSLPSEGTVFVSVANRDKRSLVFPVKRLADLGFKVLATEGTAEMLRRNGIPCDEVRKHFEEPGAGRPARSAVEAIRAGDVAMVINTPYGNSGPRIDGYEIRSAAVSMNIPCITTVQGASAAVQGIEASLRGDIGVMSLQELHSELGN
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.