PharMolix/UniProtQA huggingface dataset:
Protein: VP52B_ARATH
Sequence: MDDFSNLEKHESELGAFFGDLAFEEDSRSEDISLEGLQQELEECESDEVVANILSSGDKLREYAKGVENNLRKVELDSVEVAILLPDYIKESDKLVSLHDQIRDCNCILSQMETLLSGFQEEIGSISSDIKILQENSMDMGLRLKNRRVTESKLAKFVEDFIVPPKMIHVIVDGEVNEEYIKTLGILSKKLKFVETDQAVKSSKALKDVEPELEKLRQKAISKVYDFIVQKLIALRKPKTNIQILQQSVFLKYKYIISFLKEHGKEVFMDVRAAYIDTMNKVLSAHFQSYIQAFEKLQLDIATSNDLIGVDTRSTGLFSRSKEPLKNRCAVFALGERIQIIKEIDQPALIPHIAEASSLKYPYEVLFRSLHKLLMDTATSEYIFCEDFFGEQSIFYEIFAGPFSVIYEHLDSVLSSCYDAIGLLLMIRIIHHHQLIMSRRRIPCLDSYLDKVNISLWPRFKTVFDLHIGSLRNANINTIWEDDVHPHYIMRRYAEFTASFIHLNVEYGDGQLDINLERLRMAVDSLILKLAKLFPRPKQQMVFLINNYDMTIAVLKEAEPEGGKIQMHFEELLKSNTSLFAEELLVEHFSDMIKFVKSRANEDSSPNLERSITVAEVEPLVKDFGSRWKTAIELMHKDIITCFSNFLCGMDILIAGMTQLLLYYTRLEDCIKKIDGGSALNRDIVNYQSIMFEIKKYKKTF
What is the function of this protein?
May be involved in retrograde transport of early and late endosomes to the late Golgi.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 52 B, ARE1-like protein P2.
What is the protein family that this protein belongs to?
Belongs to the VPS52 family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein.
Protein: VATB_DEIDV
Sequence: MTLLQKEYNDVAYISGPLLFVNAASDLAYGAIVNIKDASGRSRGGQVISVTDQNAVIQVFEETRGLDLATASVSLVEDVARLGVSKEMIGRRFDGLGRPIDGLPQVVAEQRLSINGQAMNPAARAKPEEFIQTGISTIDVQTSLIRGQKLPIFSGSGLPHNELAAQIARQAKVPGHEGDFAVVFAAMGLTQREVSFFTQEFERTGALARSVLFLNKADDPAVERLLTPRMALTTAEYLAFEHGYHVLVILTDLTNYCEALREIGGAREEIPGRRGFPGYMYTDLASLYERAGVVEGKPGSVTQVPILSMPDDDITHPIPDLTGYITEGQIVVDRTLNSKGVFPPINPLPSLSRLQGNGIGKGKTRADHKNISDQLFAAYANGLDLRKLVAITGEDALTETDKLYLRFADDFEQYFIGQGDQDRSIDDSLTVAWGILSKLPQSQLTRISKDAIDKYYGTKMDEMWKGSRSLG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type beta chain is a regulatory subunit.
What are the official names of this protein?
V-type ATP synthase beta chain, V-ATPase subunit B.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: BUD4_CANAL
Sequence: MQTSISTTTIEDHLHHYSPEESQKLLSRESSINTDLFKHENESVDLLLKEMNSTPSKLLPIDKHSHLQLQPQSSSASIFNSPTKPLNFPRTNSKPSLDPNSSSDTYTSEQDQEKGKEEKKDTAFQTSFDRNFDLDNSIDIQQTIQHQQQQPQQQQQLPQTDNNLIDEFSFQTPMTSTLDLTKQNPTVDKINENHAPTYINTSPNKSIMKKATPKASPKKVAFTATNPEIHHYPDNRVEEEDQSQQKEDSVEPPSIQHQWKDPSQFNYSDEDTNASVPPTPPLHTTKPTFAQLLNKNNEVNSEPEALTDMKLKHENFSNLSLDEKVNLYLSPTNNNNSKNVSDMDSHLQNLQDASKNKTNENIHNLSFALKAPKNDIENPLNSLTNADISLRSSGSSQSSLQSLRDDNRVLESTPGSPKKVNPGLSLNDGIKGFSDEVVESLLPRDLSRDKLETTKENDAPEHNNENFIDAKSTNTNKGQLLVSSDDHLDSFDRSYNHTEQSILNLLNSASQSQISLNALEKQKQIQEQEQTQAAEPEEETSFSDNIKVKQEPKSNLEFVKVTIKKEPVSATEIKAPKREFSSRILRIKNEDEIAEPADIHPKKENEANSHVEDTDALLKKALNDDEESDTTQNSTKMSIRFHIDSDWKLEDSNDGDREDNDDISRFEKSDILNDVSQTSDIIGDKYGNSSSEITTKTLAPPRSDNNDKENSKSFEDPANNESSQQQLEVPHTKEDDSILANSSNIAPPEELTLPVVEANDYSSFNDVTKTFDAYSSFEESLSREHETDSKPINFISIWHKQEKQKKHQIHKVPTKQIIASYQQYKNEQESRVTSDKVKIPNAIQSKKFKEVNVMSRRVVSPDMDDLNVSQFLPELSEDSGFKDLNFANYSNNTNRPRSFTPLSTKNVLSNIDNDPNVVEPPEPKSYAEIRNARRLSANKAAPNQAPPLPPQRQPSSTRSNSNKRVSRFRVPTFEIRRTSSALAPCDMYNDIFDDFGAGSKPTIKAEGMKTLPSMDKDDVKRILNAKKGVTQDEYINAKLVDQKPKKNSIVTDPEDRYEELQQTASIHNATIDSSIYGRPDSISTDMLPYLSDELKKPPTALLSADRLFMEQEVHPLRSNSVLVHPGAGAATNSSMLPEPDFELINSPTRNVSNNSDNVAISGNASTISFNQLDMNFDDQATIGQKIQEQPASKSANTVRGDDDGLASAPETPRTPTKKESISSKPAKLSSASPRKSPIKIGSPVRVIKKNGSIAGIEPIPKATHKPKKSFQGNEISNHKVRDGGISPSSGSEHQQHNPSMVSVPSQYTDATSTVPDENKDVQHKPREKQKQKHHHRHHHHKQKTDIPGVVDDEIPDVGLQERGKLFFRVLGIKNINLPDINTHKGRFTLTLDNGVHCVTTPEYNMDDHNVAIGKEFELTVADSLEFILTLKASYEKPRGTLVEVTEKKVVKSRNRLSRLFGSKDIITTTKFVPTEVKDTWANKFAPDGSFARCYIDLQQFEDQITGKALQFDLNCFNEWETMSNGNQPMKRGKPYKIAQLEVKMLYVPRSDPREILPTSIRSAYESINELNNEQNNYFEGYLHQEGGDCPIFKKRFFKLMGTSLLAHSEISHKTRAKINLSKVVDLIYVDKENIDRSNHRNFSDVLLLDHAFKIKFANGELIDFCAPNKHEMKIWIQNLQEIIYRNRFRRQPWVNLMLQQQQQQQSSQQ
What is the function of this protein?
Required for establishment of the axial budding pattern in yeast cells.  May be involved in the selection of future sites of septation in hyphal cells.  Contributes to morphogenesis and is important for induction of hyphal growth.  Also plays a role in epithelial adherence, and is involved in intestinal colonization and systemic infection.  The role in adhesion is probably minor compared with its role in morphogenesis.
What are the official names of this protein?
Bud site selection protein BUD4, Alpha-INT1, Integrin alpha chain-like protein.
What is the protein family that this protein belongs to?
Belongs to the BUD4 family.
What are the subcellular locations of this protein?
Cell surface. Bud neck. Spore, perispore. Note=Localizes to a ring at the mother-bud neck of yeast and pseudohyphal cells. Localizes to single or double rings distal to the junction of the mother cell and germ tube in hyphal cells. Requires septins for proper localization. Also found at the cell-surface of blastospores.
Protein: MENG_STAA9
Sequence: MADNKANKEQVHRVFQNISKKYDRLNNIISFEQHKVWRKRVMKDMGVRKGTKALDVCCGTGDWTIALSKAVGPTGEVTGIDFSENMLEVGKEKTASMENVKLVHGDAMELPFEDNSFDYVTIGFGLRNVPDYLVALKEMNRVLKPGGMVVCLETSQPTLPVFKQMYALYFKFVMPIFGKLFAKSKEEYEWLQQSTFNFPGKEELKRMFEEAGFINVRVRSFTGGVAAMHLGYKEKDNTKGD
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
What are the official names of this protein?
Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: RL2_PECAS
Sequence: MAIVKCKPTSPGRRHVVKVVNPELHKGKPFAPLVEKNSKSGGRNNNGRITTRHIGGGHKQAYRIVDFKRNKDGIPAVVERLEYDPNRSANIALVLYKDGERRYILAPKGLKAGDQIQSGVDAAIKAGNTLPMRNIPVGSTVHNVEMKPGKGGQLARSAGTYVQIVARDGSYVTLRLRSGEMRKVESDCRATLGEVGNAEHMLRVLGKAGAARWRGIRPTVRGTAMNPVDHPHGGGEGRNFGKHPVSPWGLQTKGKKTRSNKRTDKFIVRRRTK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RS6_COXBN
Sequence: MRHYEIVILVHPDQSSQVPAMVERYQSMIKEKDGKVHRLEDWGRRQLAYSIDKVHKAHYLLMNIESDQGVISELENAFRYNDAVIRSLILKRDHAITKSSLIMQGAEKGKSSSKKVAAEAEASEEA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: MACIR_DANRE
Sequence: MEMDASGASRAPISVLPAAEVKSTLKPEADKPRCSSTPCSPIKSTVSGYQILHMNSNYLVGFTTGEELLKLAQKWSSPDSSNTEALPSPIKKPVDLGLHRASRIYKAKSRYYQPYDIPAVNGRRRRRMPSSGDSCLKSIVSGEPSKALHGPLPLCLLKGKRVYSKSLDYLNLDKMSLREPVDTEVLQYQLQHLNLRGERVFTRNKT
What is the function of this protein?
Regulates the macrophage function, by enhancing the resolution of inflammation and wound repair functions mediated by M2 macrophages.  The regulation of macrophage function is, due at least in part, to the role of C5orf30 in regulating ability to inhibit glycolysis.  Probably plays alaso a role in trafficking of proteins via its interaction with UNC119 and UNC119B cargo adapters: may help the release of UNC119 and UNC119B cargo or the recycling of UNC119 and UNC119B.  May play a role in ciliary membrane localization via its interaction with UNC119B and protein transport into photoreceptor cells.
What are the official names of this protein?
Macrophage immunometabolism regulator.
What is the protein family that this protein belongs to?
Belongs to the UNC119-binding protein family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, cilium.
Protein: MTG1_SCHPO
Sequence: MAFVARQTFEYQMPSTWYPGHMNKTLKRLKNLTSSNDIFVEVRDARIPLTSRNYVMEDFLNKKNRIIVYNKCDLADTFHTKAKVSKHRIQNLAQQFQNVECWFKETSTPEKSAFITPYVSKAPYFAKELLRLIRTLVDQASANGRVYVYFVGMPNTGKSSILNSLRNVALRKSKSAIVGNYPGVTKRISEIVRLFNDMDVYMLDTPGIMTPSITKPEDMLKLSLVGCVKEGIVHPVTVVDYLLFHLNRIDPSLYSKWSLPTNDVDEFLQNTAYKARKLTKGGFDENFVSNYVIQQYRIGRLGRFQLDTIDKNELLIRLHNEQNKKNAK
What is the function of this protein?
Mitochondrial GTPase involved in assembly of the large ribosomal subunit (By similarity).  Plays a role in expression of the mitochondrial translational machinery (By similarity).
What are the official names of this protein?
Mitochondrial GTPase 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein.
Protein: POPD3_MOUSE
Sequence: MEKNSSLWKSLVTEHPLCTTWKQEAEGAIYHLASILFVVGFMGGSGFFGLLYVFSLLGLGFLSSAVWAWVDICAADIFSWNFVLFVICFMQFVHIAYQVHSITFARDFHVLYSSLFKPLGIPLPVFRTIALSSEVVSLEKEHCYAMQGKTSIDRLSVLISGRIRVTVDGEFLHYISPFQFLDSPEWDSLRPTEEGIFQVTLTADTDCRYVSWRRKKLYLLFAQHRYISRLFSVLIGSDIADKLYALNDRVYIGKKHHYDIRLPNYYHMSTPDLSRSPLTEQFRNSRQHCNK
What is the function of this protein?
May play a role in the maintenance of heart function mediated, at least in part, through cAMP-binding.  May play a role in the regulation of KCNK2-mediated current amplitude (By similarity).
What are the official names of this protein?
Popeye domain-containing protein 3, Popeye protein 3.
What is the protein family that this protein belongs to?
Belongs to the popeye family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y1566_METJA
Sequence: MGFKYLKIKNPKVILTEWIPFGKNYMTEFIDRITLKEYQRKRIKYFTASERRDIRYKAVFETSEYQTTVNIIEFIPETSVKFTAEIIGERKKDVFIYVDYLGRCIYSSEITKAGDEEEIVSLDNLSFVIPDLILDSSRIMSHLISPPQRYLLETLYGEIKVYKHVTVLTETVVNIDENTILEISQVIGAVKNIIEIDDGLIIFGDFGIFISHKNPEKFEKFIYYYPFIRSITGVSRDLFFKLNNIASKLEVISNTLASGVDLEDITEIRGELSRIDRELAVIEIVCGYLKEIVEFLNSSYPPNFGDFDLMILEKVEAERKLRRLIYRIAEIENILKSNDSLATSLTRLLTTISEDLERKIANQLAENTKYQVAIGEAMEVLEIGIFGVYALEAAHILLLTSGKDEILHHIKILGFPLEFWIILVVTILGVYVGKIVIEYRKKKVLGE
What are the official names of this protein?
Uncharacterized protein MJ1566.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EFP_ECOL5
Sequence: MATYYSNDFRAGLKIMLDGEPYAVEASEFVKPGKGQAFARVKLRRLLTGTRVEKTFKSTDSAEGADVVDMNLTYLYNDGEFWHFMNNETFEQLSADAKAIGDNAKWLLDQAECIVTLWNGQPISVTPPNFVELEIVDTDPGLKGDTAGTGGKPATLSTGAVVKVPLFVQIGEVIKVDTRSGEYVSRVK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMC_SHEDO
Sequence: MLSNSSQVILRNSDYFQHQDVLILNYEADTLGLSLLAHAKSVTALALDFNHYLQLAAKEQPQLACFFGHTLPSSFAGKTFDSVIVFFPKAKSLAPYLFELAANHLNIDGQLMIVGDNKGGIKSVAKLIPDCFSAPVKRDNARHCLLYTCQLERQGRDFKLENWLSQYSLSTPQGEIIICNLVGVFSEKHLDLGTELLLSHLPKLEGRVLDFGCGAGVITVALLKAMPKLELECIDINAMALASCELTLQANKLQAKVYPSDGLTQVTGAFDAIISNPPFHDGLTSTTDIATQFVAMSEKQLKSKGIWQIVANRHLPYASTIAQVFGNFDVPAENNKFKLYACRKK
What is the function of this protein?
Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase C, 16S rRNA m2G1207 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RsmC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSP_BURVG
Sequence: MKHEHPDRLMNRTPLSLAALETHDAFAERHIGPDAASQQAMLDTLGFASRAALIDAVIPASIRRAEALPLGPFAQPKSEAEALAALRALADKNQVFRSYIGQGYYDSHTPAVILRNVLENPAWYTAYTPYQPEISQGRLEALLNFQQMVVDLTGLAISNASLLDEATAAAEAMTLLQRTGKPKSNVFYVADDVLPQTLEVVRTRALPIGIEVKTGPAAEAAQAGAFGVLLQYPGVNGDVRDYRALTDAIHAAGGHVVVAADLLALTVLTPPGEWGADVAVGNTQRFGVPMGFGGPHAAYMAVRDEFKRQMPGRLVGVTVDAQGKPALRLALQTREQHIRREKATSNVCTAQALLAIMASMYAVYHGPHGLKTIALRVNRIAALLAAGVKQLGFTTVNDTFFDTLTIDAGARTAQLHAFANAKRINLRRVSDTQVGVSVDETTTRDDLADLLAVFAQAAGGTAPDVDALDAGLPGVAALPAGLERTSAYLTHHVFNRHHSETEMLRYLRSLSDKDLALDRSMIPLGSCTMKLNATSEMLPVTWPEFGRIHPFAPSEQTAGYREMIDQLEQMLVAATGYAAVSLQPNAGSQGEYAGLLVIHAYHASRGEAHRDVCLIPASAHGTNPASAHMAGMKVVVVACDAQGNVDIADLKAKAEQHANDLAAIMITYPSTHGVFEQNVREICEIVHAHGGQVYVDGANMNAMVGLTAPGQFGGDVSHLNLHKTFCIPHGGGGPGVGPVAVGPHLAKFLPNQRSTGYARGEEGIGAVSAAPYGSASILPISWMYIAMMGAKNLTAATETAILNANYIAKRLAPHYPVLYSGPGGLVAHECILDLRPIKETSGITVDDVAKRLMDYGFHAPTMSFPVPGTLMVEPTESESQEELDRFIAAMIAIREEIRAVEEGRADREDNPLRHAPHTAAVVTANEWPHAYSREQAAYPVASLVTNKYWPPVGRADNAYGDRNLFCSCVPMSEYA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: RL16_AGRVS
Sequence: MLQPKRTKYRKQFKGRIKGVAKGGFDLAFGEFGLKALEPNRVNAREIEAARRAITRYMKRAGRVWIRVFPDVPVTAKPTEVRMGKGKGSVEYWACKVKPGRMMFEIDGVSEEIAREALRLGSAKLSVKTRFVQRIAE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: AROC_CALS8
Sequence: MRFLDAGETHGRCLVGIIEGFPANVKINIDNINRLLELRQRGYGRGKRMEIEKDKATILSGVRNSYTTGAPITIMIENRDYVNWQKYMDPILCDTMTKKVTVPRPGHADLPGCLKYGFDDARPVLERASARETAMRVAIGALCEELLNVFGIKLYNHVVEIGGVRIKKEYSTDDVNLFEEAENSDLFCIDKEAENDMKQVIDSAKEAGDSVGGVAEVICKNVPFGLGSHVHWDRKLDGLLAQAVMSIQSVKGVEIGMGFEVSRRFGSEVHDEIFYDDQKGFYRKTNNAGGIEGGISNGMDIVIRAAFKPIPTLYKPLRSVDLQGLKEKEAAVERSDTCAVPAGSVVMRAAVAYVLANSLIDRLSGDSLDIMIDNYKRLYQK
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: HPPA_MYXXA
Sequence: MLGGTAVVMTVDAYGPISDNAGGISEMSGLGPEVRAITDELDAVGNTTAAIGKGFAIGSATLTVIALFSAFNLEVNHTRIAAGLPEMSLQLTNPNVIVGLLLGSILPFLVGASTMLAVGRAAGAIVEEIGRQFREIPGLMELKADPDPKKIVDIATKSALQEMVFPGIIAVAAPPLVGYLLGPGALAGLLAGSLVVGATMALYMANAGGAWDNAKKFIEKGKLPGHAKGSAVHKAAVVGDMVGDPFKDTSGPGVAILIKVMSVVSLLVASLIALR
What is the function of this protein?
Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.
What are the official names of this protein?
Putative K(+)-stimulated pyrophosphate-energized sodium pump, Membrane-bound sodium-translocating pyrophosphatase, Pyrophosphate-energized inorganic pyrophosphatase, Na(+)-PPase.
What is the protein family that this protein belongs to?
Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YSDB_BACSU
Sequence: MFVMVLRIILLALFAYCIYAVVKYVANPKRRLKLAQSKEHFYIIDEQNNTRKNFQLTYKGVLFEGEKHIPSKDHPLFIHTIFVWTESPEKLKHFSAKDFENIEEKVLERYPNCKIDWDQPIKLAKKAEER
What is the function of this protein?
May mediate a negative feedback loop that down-regulates the expression of the sigma-W regulon following the activation of sigma-W in response to conditions of cell envelope stress.  Might interact with and inhibit the activity of the protease PrsW, or could bind to the anti-sigma-W factor RsiW and thereby protect it from PrsW-mediated cleavage.
What are the official names of this protein?
Sigma-w pathway protein YsdB.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RS13_PSEMY
Sequence: MARIAGVNIPDNKHTVISLTYIYGVGRTTAQKICAATGVNPAAKIKDLTDEQIEQLRGEVAKVNTEGDLRREVNMKIKRLMDLGCYRGLRHRKGLPVRGQRTKTNARTRKGPRKPIRK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: MNME_SYNP2
Sequence: MNLGDTIVAIASAVVPNQGSIGIVRLSGAAALPIARQLFQDPGQQTWESHRILYGYVRHPQTQTIVDEALLLLMLAPRSFTAEDVVEFHCHGGIIPVQQVLQLCLGAGARLATPGEFTLRAFLNGRIDLTQAESVAELVGAKSPQSAQVALAGIQGKLAQPIQQLRGQCLDILAEVEARIDFEDDLPPLDEPQIQRDLTQVLEKVAQILQTSDRGELLRTGLKVAIVGRPNVGKSSLLNAWSRSDRAIVTDLPGTTRDVVESQLVVQGIPVQVLDTAGIRDTEDAVEKIGVARSLAASQQADLILFTIDAAVGWTAADQEIFQRIVATKANQPLILILNKIDIGQPEAIEIPPQVQGVVKTAAAQHQGVDELETAIANLVQAGKVGAADLDFAINQRQAAALAQAQQALIQVRETIAQGLPLDFWTIDLRSAIQALGEITGEGVTESVLDRIFSRFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EUPC_PHOSX
Sequence: MEIANTQAAIPTIDISALLSPTASEQSRQTVINNMSDACHAYGFFNLVGHDIPPEAMRDALDCNKLFFALPQDRKMEVSIDKSIGRSFRGYEPPGIQTHHEGLLPDTKETFMVGREVMEGDPDCGSFSTGPNLWPSDLHKKGFQDRVMSYQARMLRLVETILDCLALGLPKSWNCTSHVFKPLLNKPSIPMRFLHYGPVEIHDDRQFGVADHTDFGFVSILLQEAGTSGLEVFYPPTKSWVPVPVFEQGFVINMGDMMQKHRHSVAFFLNGDLKLNAKALDGSGHETIVGEQIQQRLIETMGMTGNLLRRELV
What is the function of this protein?
2-oxoglutarate-dependent dioxygenase; part of the gene cluster that mediates the biosynthesis of eupenifeldin, a bistropolone meroterpenoid that acts as an antitumor agent (PubMed:30980906).  The first step of eupenifeldin biosynthesis is the biosynthesis of 3-methylorcinaldehyde performed by the non-reducing polyketide synthase eupA (PubMed:30980906).  Oxidative dearomatization of 3-methylorcinaldehyde likely catalyzed by the FAD-dependent monooxygenase eupB is followed by oxidative ring expansion by the 2-oxoglutarate-dependent dioxygenase eupC to provide the first tropolone metabolite, tropolone stipitaldehyde (Probable).  In parallel, generation of sesquiterpene alpha-humulene from farnesylpyrophosphate (FPP) is catalyzed by the terpene cyclase eupE (PubMed:30980906).  The cytochrome P450 monooxygenase eupD then hydroxylates humulene to humulenol (PubMed:30980906).  The putative Diels-Alderase eupF probably catalyzes the formation of the tropolone-humulene skeleton by linking humulenol and the polyketide moiety (Probable).  The short-chain dehydrogenase/reductase eupG and the flavin-dependent monooxygenase eupH are also essential for eupenifeldin biosynthesis and are likely the additional decorating enzymes of the tropolone-humulene skeleton to produce final eupenifeldin or derivatives (Probable).
What are the official names of this protein?
2-oxoglutarate-dependent dioxygenase eupC, Eupenifeldin biosynthesis cluster protein C.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: RDRP_PEMVW
Sequence: MASFLKPVNSQGLWLSLLLAITYLFLLPSAGQSLDPSGIGLAAGCSQSQGGISSFAALPRPCNDSVCTLPDLGWSCQRTAQDTANQQQSPFNHTGHFLTTSGWTWPNWTCSPSQCQLLIHLPTWQIVKQDFLLLLKEWDLLTMCQRCSDLLTKTPGFILRFAGETLILVANLIEFVLVSWSLWLCSVLVYVAQAVPGKFLLYMAAFCTTFWAWPRETASSLIRIVTTPLTLIGFLNKTGIGLISHCLALTWNMFMTWSLLPWVTLMKMMKILITSSRVLTRSGRPKRTSSKSLKHKLKISRAIQKKQGKKTPVEERTIPGVQIKKLREDPPKGVILRCTDQFGDHVGYASAVKLEKGQTGIVLPIHVWTDTVYINGPNGKLKMADFTALYEVTNHDSLIMTSAMAGWGSILGVRPRPLTTIDAVKLKNYSLFTERDGKWYVQAAKCIAPAEGMFRVVSDTRPGDSGLPLFDMKMNVVAVHRGTWPSERFPENRAFAILPVPDLTSSSSPKFTGCETYSEAETAYEMADNFSDGEEILIRTKGQSYRTFIGSNKVALLSIRKLEEELSRGPIGLWADDTEDDESAPRRSGKRIIPVDSGETKSSEDPLPKGRGVSSTPSRSKSRKGKACPSFRNDAGTEESRQPQEEKGQSCQEDSLNSTQEIQGQSTHFVPSSGTGRKSCESSPHRPTTKITSIFEDFYRWKEPREEAPGFNSVGSCPFTVYKCPPKGLSSWGERVARTSAFLQACTEKYSWPETGAEAELSSLRYQAARRQSAQTTAVIPPKDVREDLIKRTTEAYRSTALPAPMWAHNFDESHMRFEFWECVRKLKGQAGSGVPYAAFSGRKTNDKWVFDHESTEDLWETVRDRLFRLLNQDFIDPVQAVKDGLVDPIRLFVKLEPHKMEKIRNKRYRLIASVSIVDQLVARMLFRDQNEEELLQHMAIPSKPGLGFSQDHQVLAFTESVAALAGTSAQDLVDNWSRYLTPTDCSGFDWSVPMWLLEDDLAVRNELTLGLPHGLRKMRETWLKCLGQSVFCLSNGLLLAQTSPGIQKSGSFNTSSTNSRMRYMLALYAGASWAVTMGDDALESVGSDLSQYARLGIKCERAEEFDFCSHLFRAPDVVIPKNLEKMVYGLLSGTSPESPLLADRFSWLSALQSILEEMRHMPQDFVNMLIEHLGVGDLVE
What is the function of this protein?
RNA-dependent RNA polymerase that plays an essential role in virus replication.
What are the official names of this protein?
Protein P1-P2.
What is the protein family that this protein belongs to?
Belongs to the luteoviruses RNA polymerase family.
What are the subcellular locations of this protein?
[Protein P1-P2]: Membrane; Multi- pass membrane protein.
Protein: ENO_THEVO
Sequence: MELPIEDVRVRKVLDSRGNFTVEADVYIPGGFGRTSAPAGASTGETEVIAFSKKGIDESIKFFETNVRRSIIGFNALDQKGFDALITDLDGSGNFSNLGGNLSTALSMSVAKAVSAHLGIPLYRYVGGINHSMPRPIGNVIGGGKHARNGTSIQEFLVSAQGKTFMESAYVNVLVHRKIGDILSEKMKDISIGVGDERAWSVNISDEEAFEVLNQAVNEVSSETKVKIYTGLDFAADSLYENGKYVYKHTVRSRDEQIDYAISINKDFGVYYIEDPMFDTDFEGFAEITKKIGDKAMIVGDDLYTTNPDRIRKGIELGSTNAVLIKVNQIGTLTKAQEAASLASSAGLKNVVSHRSGETTDDFLAHLSVAFSSTFVKTGTIGGERIAKLNELMRIEECLTS
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RK14_HORVU
Sequence: MIQPQTLLNVADNSGARKLMCIRVIGAAGNQRYARIGDVIVAVIKDALPQMPLERSEVIRAVIVRTCKEFKCEDGIIIRYDDNAAVIIDQKGNPKGTRVFGAIAEELRELNFTKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DRS4_PHYDS
Sequence: ALWKNMLKGIGKLAGQAALGAVKTLVGAES
What is the function of this protein?
Antibacterial activity against Gram-positive bacteria S. aureus and E. faecalis, and Gram-negative bacteria P. aeruginosa and E. coli.
What are the official names of this protein?
Dermaseptin-DI4, DRS-DI4, Dermadistinctin-Q1, DD Q1.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Dermaseptin subfamily.
What are the subcellular locations of this protein?
Secreted.