PharMolix/UniProtQA huggingface dataset:
Protein: GPDA_XANAC
Sequence: MSDLTHKIAVLGAGSWGTALAALLARHGHPTVLWGRDAAMVDTIDRTHENARYLPGIALPDSLRATTDLQAAVADATWILVVVPSHAFTETIRLIAPLRPPGAGVAWATKGFEPGSGRFLHEVARDILGPSVPLAVVTGPSFAKEVTLGLPTAITVHGDDAAFAQVVADAMHGPTFRAYTGDDMVGAELGGAMKNVLAVATGVADGMQLGLNARAGLITRGLNEMLRLAAVIGARPETLMGLAGLGDLVLTCTGDLSRNRRLGLALGRGQSLDEAIREIGQVVESVQTADEVMRQAEHHGIELPISNAVRAVLHGEITPEAGLKELLARERKPEYPQTLFT
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_PARPJ
Sequence: MSASAVNVNPGRNVVVVGTQWGDEGKGKIVDWLTDHAQGVVRFQGGHNAGHTLIIGGKKTILRLIPSGIMHPGVACYIGNGVVLSPEALFKEIGELEAAGVDVQNRLFISEATTLILPYHIAIDQGREARRGAGKIGTTGRGIGPAYEDKVARRGLRVQDLFEPETFAERLRENLDYHNFVLTQYLGVAAVDFQQTLDTMLSYADRLKPMVTDVSRRLYDANAAGSNLLFEGAQGTLLDIDHGTYPYVTSSNCVAGAATAGAGVGPQKLNYILGITKAYCTRVGSGPFPSELYDADNAARQEAIGLELATVGKEFGSVTGRPRRTGWLDVAALRRSIQINGVSGLCMTKLDVLDGLDEVKLCVGYTVDGNHVDLLPRGSSEVARCEPVYETFAGWKESTVGIKEWDKLPANARAYLSRVQEVAGIPIDMVSTGPDRDETILLRHPFKV
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATXR5_RICCO
Sequence: MAPASITTTTTVARRIVGSRRRTKATSPPDSPPPKKLKPISEILAKAQYAVVERADYGDVSCMQCGSGERAEELLLCDKCDKGFHMKCVRPIVVRVPIGSWLCPKCSGQRRVRRLSQRKIIDFFRIQKCNHKTDKCSSPQDIRKHRRRSGSLVYQKRRRRLLPFVSSEDPAQRLKQMGTLASALTELQMEFSDDLTYSSGMAPRSANQARFEEGGMQVLTKEDIETLEQCRAMCKRGDCPPLLVVFDSREGFTVEADGQIKDMTFIAEYTGDVDYIRNREHDDCDSMMTLLLAKDPSKSLVICPDKRGNIARFISGINNHTLDGKKKQNCKCVRYSVNGECRVFLVATRDIAKGERLYYDYNGYEHEYPTQHFV
What is the function of this protein?
Histone methyltransferase that specifically monomethylates 'Lys-27' of histone H3 (H3K27me1).  Has much higher activity on nucleosomes containing H3. 1 than H3. 3.  Involved in the formation of constitutive heterochromatin and the silencing of heterochromatic elements.
What are the official names of this protein?
Probable Histone-lysine N-methyltransferase ATXR5.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast. Nucleus.
Protein: RUVB_PEDPA
Sequence: MEDERITSAEVQSPDEENEELSLRPQTLHQYIGQDQIKHELEVYIAAAKNREEALDHVLLYGPPGLGKTTLAMVIANEMNVQIRTTSGPAIEKPGDLVALLNELQPGDVLFIDEIHRLPKVVEEMLYSAMEDFFVDIVVGQGPTAHPIHFPLPPFTLIGATTRAGLLSAPLRDRFGIVEHMNYYNEADLANIVRRSAGIFNSHIDDQGAYEIASRSRGTPRISNRLLKRIRDFAEVENDGQIDRQLVSQSLKLLQVDNRGLDRTDKKVLTTMIELYGGGPVGISTIAANIGEEPDTISEMYEPYLLQIGFLKRTPRGRMVTERAYEHLGLIDQYMNK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: GSDC3_MOUSE
Sequence: MGYSFDRASKDVVKKLQGRDLRPVECLSDATKFRLFHILQETPRSGWETEDIPVGFTLLDLLEPNFPVPEPEVSAPKPFIHVQSTDLEANLNVADIARGGVGYVGYGGYNIEVQSTSIPNPKLEILQNRKLLDKLPTFMKFCRMERKNLYVVTEAYEVSKDTMLTGLSSVNLLVKGFFKQLFKVRGKAGRSEKYSIPIPKGSVLAYKKQQLVIENNTCVILPSATKKKMTFPGTPKYASASEPTEIYRTELQGLWINDIEPIGRIQEPAHLDFKCLQYEVSEQTRLLPELSKDVQEVVLSSFLSMLYEGDRNVLHDLMKMLELSQLGHMDGPGGKILDELRKDSSNPCVDLKDLILYLLQALMVLSDSQLNLLARSVEMRLLPHQVELVTSILQPNFKYPWNIPFTVQPQLLAPLQGEGLAITYELLEECGLKMELNNPRSTWDLEAKMPLSALYGSLSFLQQLQKANSSFKPSLRPGYI
What is the function of this protein?
Pore-forming protein that causes membrane permeabilization and pyroptosis (By similarity).  Released upon cleavage and binds to membrane inner leaflet lipids.  Homooligomerizes within the membrane and forms pores of 10-15 nanometers (nm) of inner diameter, triggering pyroptosis (By similarity).  The functional mechanisms and physiological proteases that cleave and activate this pore-forming protein are unknown (By similarity).
What are the official names of this protein?
Gasdermin-C3.
What is the protein family that this protein belongs to?
Belongs to the gasdermin family.
What are the subcellular locations of this protein?
[Gasdermin-C3]: Cytoplasm, cytosol. SUBCELLULAR LOCATION: [Gasdermin-C3, N-terminal]: Cell membrane; Multi-pass membrane protein.
Protein: LEUD_MYCMM
Sequence: MEAFDTHTGIGVPLRRSNVDTDQIIPAVFLKRVTRTGFEDGLFASWRSDPSFVLNLSPFDRGSVLVAGPDFGTGSSREHAVWALMDYGFRVVISSRFGDIFRGNAGKAGLLAAEVDQDGVELLWKLIEQSPGLEITVNLQDRNVIAGTVVLPFRIDDHTAWRLLEGLDDIALTLRKLDEIEAYEAAYPAWKPRTLPTS
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: HSLO_STRPN
Sequence: MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGRTLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATGEVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNVLLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIYGDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYNFDEKDLEELIRDKS
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNC1_YEAST
Sequence: MKTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAKNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKTTVLLDYTRPISDDPEVINKVKEELKAHNINVVDK
What is the function of this protein?
Catalyzes the deamidation of nicotinamide, an early step in the NAD(+) salvage pathway.  Positively regulates SIR2-mediated silencing and longevity by preventing the accumulation of intracellular nicotinamide, an inhibitor of SIR2, during times of stress.  Acts also on nicotinyl hydroxamate.
What are the official names of this protein?
Nicotinamidase, Nicotinamide deamidase, NAMase.
What is the protein family that this protein belongs to?
Belongs to the isochorismatase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Peroxisome. Note=Concentrates in peroxisomes (PubMed:12736687).
Protein: HIR3_YEAST
Sequence: MSMFNALNSNIEGEQYEAEEHSRELQIEQSFNILQDALIDLKNKDFEKSDSKFQELFQIDVVKPDRWGMYRNSSPTLDNLRYLCYRNRGMYYHLYLENNYERLNSQELVNCILKAVENLVESIQHSDADFAVTDLLARIFKSFNSVKLERLISEYEFTKQENLSLLLGRHRKFLLNDLTLMMNNYVELTNKLLVPNLSDNTIFERYHLEKYKDIKPEPLAFGPILSRISEMKKQDEEIMKKLDVFNVTLNEESWDEVAKALKNLLPSVKTSSLIGRNMDPYNEIEEPIEAVKFELSEAINNTPSLDRESERQEEEQDNESVRADDKSGNLAPSDIQTNEEARPNKRTDEHIDSTKPLQRSSKRFKEREQENSKELVMDVHKRFFGEFNTLLSYIHILPFCDFDTFASKFIIGSSDKQPEKFIPYTDLYECLKSWSSRYTDIFNQNDYLSSGSNENEELFQLNALLKSNAFDDKESFPRYLNDLDSDHIRSFISEVNAGNLHFHQVRLKLLFKLLGTYDEGNGRRLIIDYLWESQLLKIVLWFVFGIESNIFALINKNKRQCKYLALSIYELLVNHLGNIVEEITNKRIQGHKSADLKSQRNKVEKRIRSWHTLLEQIADEKDKELYVHFQWTHYCFLQYTCDIVDSRLSETLTSLENTIKDSDSSLDIAYPNYRHIPALNLNTVQSQKRKIRIIQNITVEDISEDTNSDTHSENHLETLEKVLLHILHPSTNHSNIDEEMVSFIFNSPFLLKIRLWGVLFSSYVKKSSIQDVQRIYFHVLDFMKGALTSPVYKESNPHGRHQMLLTVLTAIGYLSSQLTAILNSNRWESSDFVLEDYMFEKLLQTFFFFYTVLFYESSAVNDVSNKSFFKRASKSSGKMKDIMIDLATLILYYYDLQAKLRTPAEQGIETTELIWSLHTLFGHFHFCDASNGKFLDLAEKLLCQFINNDSFLQLKQILWCRYHYAIASDNFSPDLHDTKAVEMEKIHSLPLGTYLIKLQYQNKNPYLSSSKTTLKQIMDNIIEKIGDPSTLDNHIISRNSFLLNEYLSRPITADLLKHTFSGATSLYLTSPNDELQQGMTAGLFYVSSLQSLGLYKMRKKSMQARPSELDSIIRMLKNDIIYNTNRFESWILLGKCYSYIVEDDLIWTSDKITVPEKKDVIALTQRKAILCYLMAISIYYSKLDRTIDDKKIILEALDDLGSMLISGYYNPMNKLCFSWKSSAENTMRLSETGEVVMEKTKKITTISDFNIEQSIFLCFNRACSLSGDIKSQDDVFVLNWSSFYNLAKFFFKTDGGNNCKLVAKYITQGCQIAYESSPAKDPIIEPHYLLVNACYKWVKRGVIGVNEALTLLSKDNQFFQEQEEFWVNDEGLAWDYQEKFFFDKIIRLLRHLLSVDKKKWQHRPRYRIARILFDDLGDVNGALEEMDSLISAKSINKNLVNIWKPDFERPGKHFIYTYQYLVLYLDLLFAIKDFNTTGLVIKKLRRFGSGTVNVNELLERAINVYTQSAKIKLQLQDKSYVEQILPTLNYQEFLKISEQLNQVFDQGKYPEEISSGLKLAFQLKKGHSGIAFDSVCLGIYFEYLYFPLARQDQSLTDVNDENNPALPSSGSVTSKSTPDPTSKPSAIKKRVTKKEVFDRVRLLVDKIT
What is the function of this protein?
HIR1, HIR2 and HIR3 are repressors of histone gene transcription.  They are required for the periodic repression of three of the four histone gene loci during cell cycle as well as for autogenous regulation of the HTA1-HTB1 locus by H2A and H2B.  Also has a role in nucleosome assembly.
What are the official names of this protein?
Histone transcription regulator 3.
What is the protein family that this protein belongs to?
Belongs to the HIR3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localizes to the promoter region of histones HTA1-HTB1.
Protein: HUTI_RUBXD
Sequence: MSGTTLLIHDLEAAVSPKGSGPLRGRDLGELEVCSPASIAVSGDRIAAVGPPGEVLRDHPPGPGCETVDGRGKAALPGLVDCHTHAAFLGDRADEFELRCRGAGYEEIHASGGGILSTVRATRAGSEEELRAATERHLDWLLRHGTTTAEVKSGYGLDREAELRLLRAIRAAGDAHPVDVRPTFLGAHTVPPEFSGAAEYVEFVVAEVLPEAAPLAEAADVFVERGSFEVPEARRYLEACAGYGLALRLHADQFSERGAVPLAVELGARSADHLESTGGEGVRALGQSATAAVLLPACALFLGLPDPPARALLEAGAIVALATDFNPGSSFCSSLPVVLNLACTRLGLSPAEALCAATANAAYVLGLEGEVGRLSAGYRADILLLDAPDWRYIAYHLGGDHLAAVVKSGGLLPPG
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CMOB_SHEB8
Sequence: MISFSSFYQQIADSNLQHWLETLPSILGKWQRDHKHGNLPKWEKVLNKLHYPAPDQVDFVDSVTVGSGEQLSPGEKEKLENLLRLFMPWRKGPFHIHGIHIDTEWRSDWKWDRVKQHISPLKNRTVLDVGCGSGYHMWRMLGSGAKRVVGIDPSPLFLCQFEAVKRLAGTHHPVHLLPLGIEELPPLDAFDTVFSMGVLYHRRSPIDHLLQLRDQLRTGGELVLETLVIDGDENAVLVPQDRYGKMNNVWFIPSVAALMLWLKKCDFTDIRCVDTDVTALAEQRRTDWMPNESLVEYLDPNDITKTVEGYPAPKRATIIAVKNQPNQDLIS
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: RL3_YERP3
Sequence: MIGLVGKKVGMTRIFTEDGVSIPVTVIEIEANRVTQVKSLENDGYRAVQVTTGAKKANRVTKPEAGHFAKAGVEAGRGLWEFRLPEGQEFTAGQEISVEIFADVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKKMAGHMGDERVTVQSLDVVRVDAERNLLLVKGAVPGATGGNLIVKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: NDK_BRUMB
Sequence: MAIERTFSMIKPDATRRNLTGAIIAKLEEAGLRVVASKRVWMSRREAEGFYAVHKDRPFFGELVEFMSSGPTVVQVLEGENAIAKNREVMGATNPANADEGTIRKTFALSIGENSVHGSDAPETAAEEIAYWFSGTEIVG
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_SALEP
Sequence: MAVQQNKPTRSKRGMRRSHDALTAVTSLSVDKTSGEKHLRHHITADGYYRGRKVIAK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: NRDI_YERE8
Sequence: MNPLVYFSSSSQNTHRFVEKLELPAIRIPIAGTREKLRVEQPYILLVPSYGGGSPVGAVPIQVIRFLNDPHNRSLIRGVIAAGNTNFGDAYCLAGKIISQKCQVPYLYRFELLGTAEDVVNVRKGVTEFWQRQN
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: DXS_MOOTA
Sequence: MSLLEKINEPAAIKKFTLAELDILAREIRQELVQTVARTGGHLAPNLGVVELTLALHSVFDLPRDKIIWDVGHQCYVHKILTGRRQEMTSLRQFGGLSGFPKRAESPYDAFDTGHSSTSISAALGMALARDLKGEDYQVVAVIGDGALTGGMAFEAMNHAGHLQANLIVVLNDNEMSIAPPVGGLAAYLSRLRTDPMYSRGKEELENLLNRLPHLGPRVLKVIDRLKDSFKYLVVPGMFFEEIGFTYLGPIEGHNIARLKEVLQHARNTRGPVLVHVITTKGKGYQPAEDHPDRFHGIGPFDPATGEPLAGGGPPTYTSVFGAELVRQGEKNNRLVAITAAMPDGTGLTPFARRFPKRFFDVGIAEQHALTLAAGLAAAGMHPVVAIYSTFLQRAIDQVIHDIALMELPVVLAIDRAGLVGEDGETHQGLFDVSLLRCVPGLVLMAPKDEQELRHMLVTALQYQGPAALRYPRGAGMGVPLTGTAQPLPIGKGEVLRRGRDVTILALGPLAYAALEAAGDLAARGIEATVINPRFIKPLDEDLILTWADRTGHLVTVEEHVLAGGFGSAVLELLARNGRKGIRVRCLGVKDEFVHQGKPAILREHLGLTPAGIRAAVQALLAETPVLHRRRNQTKGISGG
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: YP3B_SCHPO
Sequence: MLCVRSSSSNLESDTYLSRYSTRASAGTGSTYGFGLAGDRGYSSDSSSSSSESKPSNNKNIDFIYNNNAESNLSEYLGKDIPEDLSGFRDTASAPDTQSDVRNCDSIRKYQSLSSAGSGSTYGYGAGGNRGFMDESNESPKEDYINQKKHSKLFLLLYRIFHLI
What are the official names of this protein?
Uncharacterized protein PB21E7.11.
Protein: NCE2_CANAL
Sequence: MLAIGDVILRAFNFVFLVIALGLTGSLAATTITQHNPQINFAVFAAAFGLLTSSFYGVFAYFVAAFAWPVILFVFDFLNFVFTFAAATAIAAGIRAHSCSNQDYLDDNNIAQGSSGRCRKAQASTAFLYFSTFIFIASAIFSAISLSKGGLFGHSSRPAPRTGVPTMSQV
What is the function of this protein?
Involved in membrane organization.  Involved in a novel pathway of export of proteins that lack a cleavable signal sequence.  Non-classical export pathway functions also as an alternative clearance/detoxification pathway to eliminate damaged material, when the basic repair pathway is not sufficient (By similarity).  Regulates actin organization and subsequent morphogenesis and pathogenesis.
What are the official names of this protein?
Non-classical export protein 102.
What is the protein family that this protein belongs to?
Belongs to the NCE102 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Accumulates in membrane domains at eisosomes.
Protein: RBFA_MYCGE
Sequence: MASYRKQRIENDIIRLINRTIINEIYDPVVKLGHVSHVKLSADFFHAVVYLDCYDRSQIQTVVNAFKKAQGVFSQMLAQNLYLAKSVKLHFVKDDAIDNALKIEQIINSLKN
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_TREDE
Sequence: MKNKSKYREMSYKELVSKRNDLKQKYMDLRFQAVVGHLDNPLEKRSMRREIAMLNTFIRQKELAGEGAN
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: DNAJ_CARHZ
Sequence: MKRDYYEILGVARNATPEEIKKAYRKLARKYHPDVNKDDPNAAEKFKEINEAYEVLSDPEKRARYDQFGHAGVDGNFAGQGGFGGGAGINFEDIFSGFGGFGDLFDMVFGSGRKARQGPVPGDDIEAVLELTLEEAVFGGEKELRVTRTETCGHCHGNGAEPGTPIITCPTCQGRGQIHQEVKTLFGRMVRSQVCSTCRGEGKIPKTPCRECGGSGLVRKTRSITVKIPPGIDHGHRLRIAGGGEAGRFGGPPGDLYVYIKIKPHKLFKREDIHLKLEKEISFVQAALGAKVEIPTIDGGTEILEIPEGTQTGTVFTIKGKGVPVVNGSGRGNLYVTVKVVTPTKLTERQKQLLREFEEISKQKEETFKEKFNKFKNKFAL
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HFQ_SHESA
Sequence: MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQVESFDQFVILLKNTVSQMVYKHAISTVVPARPFNVAGHQNAQGGYGAQDDMPSGE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: HIS5_VIBPA
Sequence: MTEQKVVIIDTGCANVSSVKFAIERLGYDVTISKDPQVVLSADKLFLPGVGTASEAMKNLEERDLINLVKQVEKPLLGICLGMQLLGKFSQEKGQKADELVECLGLCDGEVKLLQTGDLPLPHMGWNTVSAKAGNPLFKDIEEGEYFYFVHSFAMPVGDYTIAECDYGNPFTAAVQSGNYYGVQFHPERSSKAGAKLIQNFLEL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_PROM0
Sequence: MKNLLGSTIKDLENVALDYGQAGFRGRQIYNWIYNYRNKKKNIDQIEVLPLDFRKRLKDDGFKVSDLSIHERNLANDGTLKLLLSTEDNESIECVGIPTEKRLTACLSSQVGCPMDCKFCATGKEGLKRSLKVSEILDQILFIENEMNRKVTNIVFMGMGEPLLNIDDLLLSIRSINEDLKISQRKITVSTVAVPKMINKLSAKSFKILGNCQFTLAVSLHAPNQKIRETIIPSAKNYEIENIIEDCKQYVRDTGRRVSFEYLMLRGVNDKIEHANELSHLLKGFQCHVNLIQYNQIDEVEFQRACLKDLQSFQSRLSHNGIAVSLRKSRGLDKNAACGQLRQNARN
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_FINM2
Sequence: MARIQGVDLPNDKRVEIGLTAIYGIGRQSSNKILAKLGINPDTRVKDLTESELSDIRNELDNYLTEGDLRRDVAMNIKRLKEINCYRGSRHKKGLPVRGQHTKNNARTRKGPRKQA
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: TYPH_MYCPN
Sequence: MNIVNLISKKQRGKALTETEINWFVHSVNNKSLADYQVSAFLMAVWFQGMNSKELFCLTKAMVKSGESLHFNHHSKLSVDKHSTGGIGDKVSIALIPILTALDYSVAKLSGRGLGYTGGTIDKLEAVGVKTDFTPTEAQNLLDQNDCFIIGQSEGIAPVDKVLYALRDTTATVDSLPLIASSVMSKKLAINNDYIFIDLKYGKGAFCKTKTMAKELAQYMYSIAKQFKRKLYIKLSDMNQVLGKTIGNALEVLEVVHFLKRNWTEVGADFIQLMEQIVTEILIETKRAPNKRAAVALYHATLEGEKPWQRFLKFIELQGSSWERFLDLKELFNPQYKAPVLASQSGTLSYTSPVDLAMVSISLGAGRMVKTDLIDPMAGIKLVKQANEVVKAGDTVLELYSSKPITPAHIEAAQHTIIIKQ
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: DUSTY_APIME
Sequence: MVSKLPQEFRRYLRNRNQLQHVLEETQQALELINLENFFPEENVVEELLSPLTLNRITHILANSPAIIILGQDSKAKAIVVNTLISNDILPVCNGLWRWIRLTYGQTNHISLTLDLEYELVENLQANEKPWSTLPIEDLTKSDNEDITYPTVLEVQLNLPILKDGVQIFIAPNNGAVKVLANEFLSILPIFLYALGEQPLTEQNLEELRDLKETYPFNPVLFISSLENISLNGIDPELTESEQHRLQNRLYTNDSTSSKTDDDSIDFDRMNSLGLSWLDQLTNLGFLGMKESVEVDQLSWLGSGQYISDFVGSCRKTDQILYFIRGCLQTYLINASTYLNEVHTASLRKFILSAFDMARIIQITPKRIQYAQHKENELYANLMKIVHEKQQEITGLIQNIIQEMKNDVLLSNNDVYLYQNTMSNNNQRTEWSATVKAAISEVQRVVLGRLCEKVAKQLVNSVNCLRESFIGTLQRCLLSLEKTYERDTCLLASDALKQILSAAYNVELHNSSPFSIYSFLERLNLIFMSSSLQWSSTHTLDVAWRRKVTIEILNSLSATKLSKIILMQFGDKLESSHDSFQAALRSIENYYSGKLERTEEQRIALRKYHAPRLAKLALESTSMIDVVRYGKPHCAEEIGRGQYGIVFACDGWGGKAGPCAIKSVVPSDESHWNDLAMEFYYNRSIPDHKRIVKLRGSIIDHSYGGGFGFGSAVLLISDRLSRDLYCGIRAGLSWLERIQIALDVLEGIRYLHSQGLVHRDVKLKNVLLDIENRAKLTDFGFCITEVMMLGSIVGTPVHMAPELLSGHYDSSVDVYAFGILFWYLCAGHVRLPYTFEQFHNKELLWTSVKKALMIVGIRPERLPSFDDECWRLMEQCWSGEPSKRPLLGAIVPVLESIQQKAKRSKSLQEVSSDKLQESSTDSRNPALALAEPYNQRGTVVSPPPTKRRTMKVVKYHLFLTNLYIQMREL
What are the official names of this protein?
Dual serine/threonine and tyrosine protein kinase, Dusty protein kinase, Dusty PK, Receptor-interacting serine/threonine-protein kinase 5.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm.