PharMolix/UniProtQA huggingface dataset:
Protein: PIPS_MYCTO
Sequence: MSKLPFLSRAAFARITTPIARGLLRVGLTPDVVTILGTTASVAGALTLFPMGKLFAGACVVWFFVLFDMLDGAMARERGGGTRFGAVLDATCDRISDGAVFCGLLWWIAFHMRDRPLVIATLICLVTSQVISYIKARAEASGLRGDGGFIERPERLIIVLTGAGVSDFPFVPWPPALSVGMWLLAVASVITCVQRLHTVWTSPGAIDRMAIPGKGDR
What is the function of this protein?
Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP.  PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid for mycobacteria required for formation of their cell wall.
What are the official names of this protein?
Phosphatidylinositol phosphate synthase, PIP synthase, CDP-diacylglycerol--D-myo-inositol-3-phosphate 3-phosphatidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FLP_KLULC
Sequence: MSTFAEAAHLTPHQCANEINEILESDTFNINAKEIRNKLASLFSILTMQSLSIRREMKINTYRSYKSAIGKSLSFDKDDKIIKFTVRLRKTESLQKDIESALPSYKVVVSPFKNQEVSLFDRYEETHKYDASMVGLQFTNILSKEKDIWKIVSRIACFFDQSCVTTTKRAEYRLLLLGAVGNCCRYSDLKNLDPRTFEIYNNSFLGPIVRATVTETKSRTERYVNFYPVNGDCDLLISLYDYLRVCSPIEKTVSSNRPTNQTHQFLPESLARTFSRFLTQHVDEPVFKIWNGPKSHFGRHLMATFLSRSEKGKYVSSLGNWAGDREIQSAVARSHYSHGSVTVDDRVFAFISGFYKEAPLGSEIYVLKDPSNKPLSREELLEEEGNSLGSPPLSPPSSPRLVAQSFSAHPSLQLFEQWHGIISDEVLQFIAEYRRKHELRSQRTVVA
What is the function of this protein?
Catalyzes the recombination between the large inverted repetitions of the plasmid.
What are the official names of this protein?
Recombinase Flp protein.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family.
Protein: MTGA_NEIG2
Sequence: MFRIVKWLIALPVGIFIFFNAYVYGNIITYRAVAPHRTAFMSMRMKQFEQEGRDVALDYRWVPYNRISTNLKKALIASEDVRFAGHGGFDWGGIQNAIRRNRNSGEVKAGGSTISQQLAKNLFLNESRNYLRKGEEAAITAMMEAVTDKNRIFELYLNSIEWHYGVFGAEAASRYFYKKPAADLTKQQAAKLTALVPAPLYYADHPKSKRLRNKTNIVLRRMGSAELPESDTD
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RECA_RICFE
Sequence: MSNTDKERAIAAALAQIEKSYGKGSVMKLGQRPNIDIEAVSTGSLGLDIALGIGGVPKGRIIEIFGPESSGKTTLTLHLIAEAQKKGGTCAFIDAEHALDPAYAKKLGVNIDELIISQPDTGEQALEIADTLIRSGGIDMIIIDSVAALVPKSEIEGEMGDAQMASQARLMSQALRKLTASINRTNCITVFINQIRMKIGVMFGNPETTTGGNALKFYASVRIDIRRIGSIKDKEEVIGSQTKVKVVKNKVSPPFKTADFDIMYGSGISKEGEIIDLGVKLDIVEKSGSWFSYNNVRIGQGRENVKQYLKEHPQISNEIEKIIREKSSKITNINLDQTEEEND
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PARE_STAAS
Sequence: MNKQNNYSDDSIQVLEGLEAVRKRPGMYIGSTDKRGLHHLVYEIVDNSVDEVLNGYGNEIDVTINKDGSISIEDNGRGMPTGIHKSGKPTVEVIFTVLHAGGKFGQGGYKTSGGLHGVGASVVNALSEWLEVEIHRDGNIYHQSFKNGGSPSSGLVKKGKTKKTGTKVTFKPDDTIFKASTSFNFDVLSERLQESAFLLKNLKITLNDLRSGKERQEHYHYEEGIKEFVSYVNEGKEVLHDVATFSGEANGIEVDVAFQYNDQYSESILSFVNNVRTKDGGTHEVGFKTAMTRVFNDYARRINELKTKDKNLDGNDIREGLTAVVSVRIPEELLQFEGQTKSKLGTSEARSAVDSVVADKLPFYLEEKGQLSKSLVKKAIKAQQAREAARKAREDARSGKKNKRKDTLLSGKLTPAQSKNTEKNELYLVEGDSAGGSAKLGRDRKFQAILPLRGKVINTEKARLEDIFKNEEINTIIHTIGAGVGTDFKIEDSNYNRVIIMTDADTDGAHIQVLLLTFFFKYMKPLVQADRVFIALPPLYKLEKGKGKTKRVEYAWTDEELNKLQKELGKGFTLQRYKGLGEMNPEQLWETTMNPETRTLIRVQVEDEVRSSKRVTTLMGDKVQPRREWIEKHVEFGMQEDQSILDNSEVQVLENDQFDEEEI
What is the function of this protein?
Topoisomerase IV is essential for chromosome segregation.  It relaxes supercoiled DNA.  Performs the decatenation events required during the replication of a circular DNA molecule.
What are the official names of this protein?
DNA topoisomerase 4 subunit B, Topoisomerase IV subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase family. ParE type 2 subfamily.
Protein: YWDJ_BACSU
Sequence: MKLVLGALQWTAFIIAAAIVVPVAVAQSFHLDHSDSARLIQSTFFVLGIAAVIQCLKGHRLPINESPAGLWWGVYTIYAGLTGTVFATYGDTLRGLQGALLVSAVCFFLLSVFKVIDRLAKLFTPVVTGVYLLLLVMQLSQPIIKGILGIGYRQDGVDGLVFGLALVVIAAAFIMTNSNIMFFKQYSILLALFGGWVLFAAAGAAKPIEMPDRLFQLPSLFPFGTPLFNSGLIITSIFITILLIVNMLASMKVVDIAMKKFSKQPDGKHHERHAGFAASFSHLLSGLTGAIAPVPISGAAGFIETTKMPSKKPFMLGSILVIVISVIPFFMNTFASLPSPVGFAVNFVVFSAMGGLAFAEFDSYEKEESKRVRSIIGISLLTGVGIMFVPETALKGLHPVFISLLSNGLVLGTLAAIAADQFQLWRRRKSDNLVSTENKH
What are the official names of this protein?
Putative purine permease YwdJ.
What is the protein family that this protein belongs to?
Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL7_THEVB
Sequence: MSAATDEILEKLKSLTLLEAAELVKQIEETFGVSAAAPVGGMMVAAPVAGAAAAPAEEVEEKTAFDVILEEVPADKKIAVLKVVRSLTGLGLKEAKEVVESTPKPVKEGASKEDAEAAKKELEEAGAKVSIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: PSBF_EPHSI
Sequence: MTIDRIYPIFTVRWLAIHGLAVPTVFFLGSISAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: STHA_PSEMY
Sequence: MAVYNYDVVVLGSGPAGEGAAMNAAKAGRKVAVVDNRPLVGGNCTHLGTIPSKALRHSVRQIMQFNTNPMFRQIGEPRWFSFPDVLKSAEKVIAKQVTSRTGYYARNRIDTYFGTASFADEQTVEVVCLNGVVEKLVAKQIVIATGSRPYRPADVDFRHPRIYDSDTILSLGHTPRRLIIYGAGVIGCEYASIFSGLGVLVDLIDNRDQLLSFLDSEISDALSYHLRNNNVLIRHNEEYERIEGVENGVVLHLKSGKKIKADALLWCNGRTGNTDQLGLENIGIAVNSRGQIQVDEHYRTEVSNIYAAGDVIGWPSLASAAADQGRSAAGSIVENGSWRFVDDVPTGIYTIPEISSIGKTERELTQAKVPYEVGKAFFKGMARAQISVEPVGMLKILFHRETLEVLGVHCFGYQASEIVHIGQAIMNQKGEANSIKYFINTTFNYPTMAEAYRVAAFDGLNRLF
What is the function of this protein?
Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
What are the official names of this protein?
Soluble pyridine nucleotide transhydrogenase, STH, NAD(P)(+) transhydrogenase [B-specific].
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTPB_STAES
Sequence: MKIIFVCSGNTCRSPLAESIAKSLLPHDSIASRGLFAVEGQAISKESLELIHKYDLPEPSRAQAFHIDDLDADIILTMTQAHKDLIFSMYGRQSNVFTLNEYVGDTQEIDDPFGGSFDVYEQTYTKIYDLVDKIKFKHE
What is the function of this protein?
Dephosphorylates the phosphotyrosine-containing proteins.
What are the official names of this protein?
Low molecular weight protein-tyrosine-phosphatase PtpB, Phosphotyrosine phosphatase B, PTPase B.
What is the protein family that this protein belongs to?
Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
Protein: HIS7_METS3
Sequence: MDRKSNVSRTTSETDIQIEMNLDGKGKYNISTGVNFFNHMLEAFSKHSMIDLVVDAKGDIEIDDHHTIEDVGILLGEAFRQAIGDKRGIKRMADATVPMDESVAKVAIDISGRSYCNMEFDFTNEKIGDMTSEIVVHFFESFVSSAKLNIYGVSKGANDHHQAEAVFKAFAKSLKEAIKIEHDEIPSTKGVL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACTT3_MOUSE
Sequence: MSGYQPPVVIDNGSGMIKAGLAGTREPQFVYPNILGRSKGHTADSRQELCVGDQAQERRSFLSISYPVERGLISSWGDMEIMWKHIYDYNLNLNASDGPVLVTEPALNPLADRQHISEVFFENLGVPAFYMSAQAVLALFAAGFTTGLVLNSGAGITQCVPIFEGYCLSHGVKQLNVAGSDLTSYLMMLLKGDGIMLLRTGDRKVVTDIKENACYVAMNYEDEMTKDSNLEKIYTLPDGKTVKLHKQLFHCPEALFSPYLVNVDAPGIDKMCFGSIMKCDTDLRNSFFSNIILSGGSTSFPGLDKRLIKDVAKLAPANTAVQVIAPPERKISVWMGGSILASLSAFQDMWITAAEFEEVGPNIVHQRCF
What are the official names of this protein?
Actin-related protein T3, ARP-T3, Actin-related protein M1.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm. Nucleus. Note=The localization changes from the peripheral region to inside the nucleus during differentiation from round to elongated spermatid.
Protein: RL33_STRP4
Sequence: MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVVFTEVK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: PYL5_ORYSJ
Sequence: MVGLVGGGGWRVGDDAAGGGGGGAVAAGAAAAAEAEHMRRLHSHAPGEHQCSSALVKHIKAPVHLVWSLVRSFDQPQRYKPFVSRCVVRGGDLEIGSVREVNVKTGLPATTSTERLELLDDDEHILSVKFVGGDHRLRNYSSIVTVHPESIDGRPGTLVIESFVVDVPDGNTKDETCYFVEAVIKCNLTSLAEVSERLAVQSPTSPLEQ
What is the function of this protein?
Intracellular abscisic acid (ABA) receptor that functions as a positive regulator of ABA signaling pathway (PubMed:22071266, PubMed:24474809).  Together with ABI5, PP2C30 and SAPK2, is part of an ABA signaling unit that modulates seed germination and early seedling growth (PubMed:22071266).  Acts as positive regulator of abiotic stress-responsive gene expression (PubMed:24474809).  Inhibits the protein phosphatases PP2C06 and PP2C09 when activated by ABA (PubMed:24743650).
What are the official names of this protein?
Abscisic acid receptor PYL5, PYR1-like protein 11, OsPYL11, PYR1-like protein 5, OsPYL5, Regulatory components of ABA receptor 5.
What is the protein family that this protein belongs to?
Belongs to the PYR/PYL/RCAR abscisic acid intracellular receptor family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol.
Protein: MRTFA_MOUSE
Sequence: MTLLEPEMLMMAVQSVLQLKLQQRRTREELVSQGIMPPLKSPAAFHEQRRSLERARTEDYLKRKIRSRPERAELVRMHILEETSAEPSLQAKQLKLKRARLADDLNEKIAQRPGPMELVEKNILPVESSLKEAIIVGQVNYPKVADSSSFDEDSSDALSPEQPASHESQGSVPSPLESRVSDPLPSATSISPTQVLSQLPMAPDPGETLFLAEQPPLPPAPLLPPSLANGSIVPTAKPAPTLIKQSQPKSASEKSQRSKKAKELKPKVKKLKYHQYIPPDQKQDKGAPAMDSSYAKILQQQQLFLQLQILNQQQQQQQQQHYNYQAILPAPPKPSAETPGSSAPTPSRSLSTSSSPSSGTPGPSGLARQSSTALAAKPGALPANLDDMKVAELKQELKLRSLPVSGTKTELIERLRAYQDQVSPAPGAPKAPATTSVLSKAGEVVVAFPAALLSTGSALVTAGLAPAEMVVATVTSNGMVKFGSTGSTPPVSPTPSERSLLSTGDENSTPGDAFGEMVTSPLTQLTLQASPLQIVKEEGARAASCCLSPGARAELEGLDKDQMLQEKDKQIEELTRMLQQKQQLVELLRLQLEQQKRAQQPAPASSPVKRESGFSSCQLSCQPQGSAHAFGSGLVVPTTNHGDTQAPAPESPPVVVKQEAGPPEPDLAPSSQLLLGSQGTSFLKRVSPPTLVTDSTGTHLILTVTNKSADGPGLPAGSPQQPLSQPGSPAPGPPAQMDLEHPPQPPFATPTSLLKKEPPGYEETVTQQPKQQENGSSSQHMDDLFDILIQSGEISADFKEPPSLPGKEKSPPAAAAYGPPLTPQPSPLSELPQAAPPPGSPTLPGRLEDFLESSTGLPLLTSGHEGPEPLSLIDDLHSQMLSSSAILDHPPSPMDTSELHFAPEPSSGMGLDLAVGHLDSMDWLELSSGGPVLSLAPLSTAAPSLFSMDFLDGHDLQLHWDSCL
What is the function of this protein?
Transcription coactivator that associates with the serum response factor (SRF) transcription factor to control expression of genes regulating the cytoskeleton during development, morphogenesis and cell migration (PubMed:12019265, PubMed:12732141, PubMed:17588931, PubMed:19350017, PubMed:24732378).  The SRF-MRTFA complex activity responds to Rho GTPase-induced changes in cellular globular actin (G-actin) concentration, thereby coupling cytoskeletal gene expression to cytoskeletal dynamics (PubMed:24732378).  MRTFA binds G-actin via its RPEL repeats, regulating activity of the MRTFA-SRF complex (PubMed:12732141, PubMed:17588931).  Activity is also regulated by filamentous actin (F-actin) in the nucleus (PubMed:23558171, PubMed:25759381).
What are the official names of this protein?
Myocardin-related transcription factor A, MRTF-A, Basic SAP coiled-coil transcription activator, MKL/myocardin-like protein 1, Megakaryoblastic leukemia 1 protein homolog, Megakaryocytic acute leukemia protein homolog.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Subcellular location is tightly regulated by actin both in cytoplasm and nucleus: high levels of G-actin in the nucleus observed during serum deprivation lead to low levels of nuclear MRTFA, while reduced levels of nuclear G-actin result in accumulation of MRTFA in the nucleus (PubMed:17588931, PubMed:21673315). G-actin-binding in the cytoplasm inhibits nuclear import by masking the nuclear localization signal (NLS) (PubMed:17588931, PubMed:21673315). In contrast, binding to nuclear globular actin (G-actin) promotes nuclear export to the cytoplasm (PubMed:17588931). Nuclear localization is regulated by MICAL2, which mediates depolymerization of nuclear actin, which decreases nuclear G-actin pool, thereby promoting retention of MRTFA in the nucleus and subsequent formation of an active complex with SRF (By similarity).
Protein: PYRB_DESVM
Sequence: MQHAQRPTWPHKDLLDVTQLTRAELFHLLDTAAQFHDINRRPVKKVPTLKGKSVVLFFAEPSTRTKTSFDVAGKRLSADTFSLAKSGSSLSKGESLKDTALTLQAMTPDIIVIRHSSSGAAQFLAERLDCSVVNAGDGWHAHPTQALLDCYSLRQVWGDTFEGRTLLILGDIAHSRVARSNVHLLSSLGVKVRLCAPRTLLPAGVHNWPVTIFNRLDDAVQGVDAVMCLRLQLERQQAGLLPDLREYAQRFCLSPRHLTMAAPSARVLHPGPMNRGLEISSVLADAPESLILDQVAAGVATRMAILFLLATRTGIEQTADNGGRA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: NUD17_MOUSE
Sequence: MAAARLLLRLAGRLESVSFTQSVCGLLGAGQRPGPWHTHCSLERGQLVLSSNPFPGASERLPIQRPLFCPFAALDQQPEVSKTEPLTNRGVDLGVAVILQSSDQTVLLTRRTCTLRISPNLWVPPGGHMEPDEEILECGFRELWEECGLQLPKNQFSCVLLGLWESAYPPRLSWGFPKYHHLILYVLVISQESQEQLQARIQVNPNEVNAFMWLGPDVAAAVVATEDGTRTPGLFSQDLPLSVCATELKDDGGTQPLVLPMPTLMRTTPTTAEEDKERIGAGTKFALQLWLQHLGR
What is the function of this protein?
Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.
What are the official names of this protein?
Nucleoside diphosphate-linked moiety X motif 17, Nudix motif 17.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
Protein: RL22_LACJO
Sequence: MAEQISSAKAEARTVRIAPRKARLVVDLIRGKSVAEALAILQFTPRAASPIVEKVLKSAIANAEHNYDLESANLYVSEAYVNEGATLKRFRPRAKGMASPINKRTSHVVVVVSEKND
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: URE2_MARN8
Sequence: MIPGEYQLKDGDIELCAGRERIQLDVGNTGDRPVQIGSHYHFAEANPALDFDRVKVRGYRLDVAAGTAIRFEPGQTRSVTLIPFAGTREIYGFRGEVMGSLDSTN
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_THEYD
Sequence: MKGKMLLIFMMIVMIASSAMAAEAEHAGGDLKDWAFKVINFAILVFIIVKFLGKPIKNYFAQRKELIEKSIRESQEAKELAQKALQEVEEKLKLKDKEVQDILDTAKKIGEQEKIQIVQESEKLKEKILEQAKTNIEFEVKMAKDALRLEAAELAIQLSEQKLKEKITPEEQEKLLQESIKIIEGRKN
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: Y004_MYCUA
Sequence: MNGDGEQPGPGDGAARDELPSMDLVRRTLAEARAAARARGQDPGRGFAAGPAPRRVAGRRRSWSGPGPDTRDPQPLGKLTRDLAKKRGWSGHVAEGTVLGQWSQVVGAQIADHATPTALNEGVLSVTAESTAWATQLRIMQSQLLAKIAAAVGNGVVTSLKITGPASPSWRKGPRHIAGRGPRDTYG
What are the official names of this protein?
UPF0232 protein MUL_0004.
What is the protein family that this protein belongs to?
Belongs to the UPF0232 family.
Protein: EFP_CHLPD
Sequence: MTSISNVSKGSIIRFKGEPHIIESLIHRTPGNLRAFYQANMKNLKTGRNVEFRFSASESVDVIVTERKPYQYLYKDGTDFVMMDSGTFDQINVPEITLGTSSRFLKDGITVVIVFSDDGSILDVEMPTFVEVEVTETSPTTKDDRATSGTKPAIVETGAEVGVPMFIQTGSIIRVDTRTGEYIERVKK
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGB_HAEI8
Sequence: MTTAVTQATIDGFFDASNGDPFATLGMHETEQGIEIRTLLPDANRMVVIERESGKEITELDCVDERGFFVGVIPNCRQFFAYQLQVFWGNEAQIIEDPYRFHPMIDDLEQWLLSEGSMLRPYEVLGAHFMECDGVSGVNFRLWAPNARRVSIVGDFNYWDGRRHPMRFHPKSGVWELFLPKASLGQLYKFELIDCYGNLRLKADPYAFSSQLRPDTASQISALPNVVEMTEQRRQANQANQPISIYEVHLGSWRRNLENNFWLDYDQIADELIPYVKEMGFTHIEFLPLSEFPFDGSWGYQPLGLYSPTSRFGSPEAFRRLVKRAHEAGINVILDWVPGHFPSDTHGLVAFDGTALYEHEDPREGYHQDWNTLIYNYGRNEVKNFLSSNALYWLERFGVDGIRMDAVASMIYRDYSRAEGEWIPNQYGGRENLEAIEFLKHTNWKIHSEMAGAISIAEESTSFAGVTHPSEDGGLGFNFKWNMGWMNDTLAYMKLDPIYRQYHHNKMTFGMVYQYSENFVLPLSHDEVVHGKYSLLGKMPGDTWQKFANLRAYYGYMWGYPGKKLLFMGNEFAQGREWNYEESLDWFLLDENIGGGWHKGVLKLVKDLNQIYQKNRPLFELDNSPEGFDWLVVDDAANSVFAFERRSSNGERIIVVSNFTPVPRHNYRIGVNVAGKYEEILNTDSMYYEGSNVGNFGCVASEKIESHGRENSISVSIPPLATVYLRLKAK
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: FAL1_NEOFI
Sequence: MADGIDRRTDDRLEFSTSKEVTVAPTFEDMHLKESLLRGIYAYGYESPSAVQSRAIVQICKGRDTIAQAQSGTGKTATFSISILQVIDTVVRETQALVLSPTRELATQIQSVIMALGDYMNVQCHACIGGTNIGEDIRKLDYGQHVVSGTPGRVADMIRRRHLRTRHIKMLVLDEADELLNRGFREQIYDVYRYLPPATQVVVVSATLPYDVLDMTTKFMTDPVRVLVKRDELTLEGIKQYFIAVEKEEWKFDTLCDLYDTLTITQAVIFCNTRRKVDWLTDKMREANFTVSSMHGEMPQKERDSIMQDFRQGNSRVLISTDVWARGIDVQQVSLVINYDLPTNRENYIHRIGRSGRFGRKGVAINFVTSDDVRILRDIELYYSTQIDEMPMNVADLLS
What is the function of this protein?
ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis.  Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase fal1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX48/FAL1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PURL_SYNSC
Sequence: MVSSPAYDIAAALKQEGLKPSDWDEICRRLGREPNRAELGMFGVMWSEHCCYRNSRPLLSGFPTEGPRILVGPGENAGVVDLGGGHRLAFKIESHNHPSAVEPFQGAATGVGGILRDIFTMGARPIALLNALRFGPLEDPANVGLMEGVVAGIAHYGNCVGVPTVGGEVAFDPSYSGNPLVNAMALGLMETEEIVKSGAIGVGNPVVYVGSTTGRDGMGGASFASAELSADSLDDRPAVQVGDPFLEKGLIEACLEAFASGDVVAAQDMGAAGLTCSCSEMAAKGGLGVELDLDRVPARETGMTAYEFLLSESQERMLFVVKAGREDALMQRFRRWGLQAALVGKVLQEPIVRVLHHGAVAAEVPATALADDTPIEKHALLQEPPADLQALWGWTEQELPVLSDAAAALLQLLDDPTIASKQWVHRQYDQQVLANTVVSSGAADAAVVRLRPQQGNGSMAASNRGVAATVDCPNRWVALDPERGAQAAVAEAARNLSCVGAEPLAVTDNLNFPSPETPKGFWQLAMACRGISDACRTLNTPVTGGNVSLYNETKQDDGTMQPIHPTPVIGMVGGVDDISRVTCLAWQQPGDAIFLIGVPPEDGADPSLGLAGSAYQQQTLGSLAGRPPKPDLAIEAAVGSLVREAIAQGLLASAHDCSDGGLAVALAESCIASDLGISVTLSTGSARLERVLFAEGGSRVIVSVNAASFPAWEQLIGSNPALCVTQLGSVTLEARLVIRSESAVQLDLEVERCAAVFRDALPRRMHSE
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_LACLS
Sequence: MNLIDGKALAAKMQAELKVKVDKLKEAGSVPGLAVILVGEDPASQIYVRNKARQATAIGLNSSVVRLPETVSEKELLELIEQYNQSEQWHGILVQLPLPKHISEEKVLLAIDPEKDVDGFHPMNMGRLWAGNPLMIPSTPAGIMEMFREYNVELSGKRAVVIGRSNIVGKPMAQLLMMADATVTIAHSRTKNLRELTKEADILVVAIGRDRMIKADDVKDGAVVIDVGMNRDEDGKLHGDVDFDEVKEVASLITPVPGGVGPMTITMLMEQTVRAATRKMNENSN
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.