PharMolix/UniProtQA huggingface dataset:
Protein: CP2W1_HUMAN
Sequence: MALLLLLFLGLLGLWGLLCACAQDPSPAARWPPGPRPLPLVGNLHLLRLSQQDRSLMELSERYGPVFTVHLGRQKTVVLTGFEAVKEALAGPGQELADRPPIAIFQLIQRGGGIFFSSGARWRAARQFTVRALHSLGVGREPVADKILQELKCLSGQLDGYRGRPFPLALLGWAPSNITFALLFGRRFDYRDPVFVSLLGLIDEVMVLLGSPGLQLFNVYPWLGALLQLHRPVLRKIEEVRAILRTLLEARRPHVCPGDPVCSYVDALIQQGQGDDPEGLFAEANAVACTLDMVMAGTETTSATLQWAALLMGRHPDVQGRVQEELDRVLGPGRTPRLEDQQALPYTSAVLHEVQRFITLLPHVPRCTAADTQLGGFLLPKGTPVIPLLTSVLLDETQWQTPGQFNPGHFLDANGHFVKREAFLPFSAGRRVCVGERLARTELFLLFAGLLQRYRLLPPPGVSPASLDTTPARAFTMRPRAQALCAVPRP
What is the function of this protein?
A cytochrome P450 monooxygenase that may play a role in retinoid and phospholipid metabolism (PubMed:22591743, PubMed:26936974).  Catalyzes the hydroxylation of saturated carbon hydrogen bonds.  Hydroxylates all trans-retinoic acid (atRA) to 4-hydroxyretinoate and may regulate atRA clearance.  Other retinoids such as all-trans retinol and all-trans retinal are potential endogenous substrates (PubMed:26936974).  Catalyzes both epoxidation of double bonds and hydroxylation of carbon hydrogen bonds of the fatty acyl chain of 1-acylphospholipids/2-lysophospholipids.  Can metabolize various lysophospholipids classes including lysophosphatidylcholines (LPCs), lysophosphatidylinositols (LPIs), lysophosphatidylserines (LPSs), lysophosphatidylglycerols (LPGs), lysophosphatidylethanolamines (LPEs) and lysophosphatidic acids (LPAs) (PubMed:22591743).  Has low or no activity toward 2-acylphospholipids/1-lysophospholipids, diacylphospholipids and free fatty acids (PubMed:26936974, PubMed:22591743).  May play a role in tumorigenesis by activating procarcinogens such as aflatoxin B1, polycyclic aromatic hydrocarbon dihydrodiols and aromatic amines (PubMed:20805301, PubMed:16551781, PubMed:24278521).  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase) (PubMed:22591743, PubMed:26936974).
What are the official names of this protein?
Cytochrome P450 2W1, CYPIIW1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen. Cell membrane. Microsome membrane. Note=About 8% are expressed on the cell surface.
Protein: DXR_VIBVY
Sequence: MQKLTILGATGSIGASTLKVIEQNPDKFSVVALAADSNVEKMQQLCQRWQPEFAVMANKEAALRLKMALAVLAPNTQVLGGQEALCYVATLEQVDSVMAAIVGAAGLVPTMAAVKAGKRILLANKEALVMSGQLFIDEVEKSGAQLLPVDSEHNAIFQCLPQAVQGNLGRCDLASQGVSHILLTGSGGPFRYTDVAELEAVTPEQAIAHPNWSMGPKISVDSATMMNKGLEYIEAKWLFNANRDQLKVIIHPQSVIHSMVQYLDGSVLAQMGEPDMATPIALTLSYPERVKAGVKPLDFTQVGELTFLQPDFERYPCLALAIEACYLGQHATTTLNAANEVAVAAFLARQIKFTDIARVNDSVLNQVCKQSLASGLDSLESLLELDRMARTLADEVVRERAQ
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: RBFA_ACTP2
Sequence: MSREFKRSDRVAQELQKEIAVILQREVKDPRIGMVTVSDVEVSRDLAYAKIFVTFLFDNDQSVIEQGMKGLEKASPYIRSLVGKAMRLRIVPELRFIYDQSLVEGMRMSNLVSNVIKNDEAKHKEEE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_POLSJ
Sequence: MLAKRIIPCLDVTGGRVVKGVNFVELRDAGDPVEIAARYNEQGADELTFLDITATSDGRDLILHIIEAVASQVFIPLTVGGGVRTVEDVRRLLNAGADKTSFNSAALANPQVIEDASAKYGAQCIVVAIDAKRRSEEDARTRGAGWDVYSHGGRKNTGLDAVAWATEMARRGAGEILLTSMDRDGTKSGFDLALTRAVSDAVDVPVIASGGVGNLDHLADGIQLGGADAVLAASIFHYGEYTVQQAKQHMARRGIPVRM
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDD_STRP7
Sequence: MKRILIAPVRFYQRFISPVFPPSCRFDLTCSNYMIQAIEKHGFKGVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YL208_MIMIV
Sequence: MIFCEKCRYSFNITKDVKSVQVGGKVNIALNNLFGKFNKNQQIVESDLTKLKVTDVLYDERFENMTKKDKKKMMSLIKSVNKSFFQEVGGQGELNTNKAYFICKYCKNYRPIEAGTTIYTKNYDTTDNSDIENYSFYIHDHTLQRTKNYICKNKDCKTHQNDNLKEAVLAKNSADQLVYVCTACTTHWINSI
What are the official names of this protein?
Uncharacterized protein L208.
What are the subcellular locations of this protein?
Virion.
Protein: NACA_CANAL
Sequence: MSIEEIPQGADVNVIPKNEKKARELIKKLNLKQIKGISRVTFKQRGNLIYAIDSPDVYRSAAGTYVVFGEAKVDDMNQRIAEAQAQQAQQEALQKAAADAGKTEDKSPEAITADLEKASLGDKKAEDEEEDEGEIDETGLDPKDIEIVVEQTQVSRAKAVKALRNHDGDMVNAIMDLS
What is the function of this protein?
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting.  The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum.  EGD2 may also be involved in transcription regulation (By similarity).
What are the official names of this protein?
Nascent polypeptide-associated complex subunit alpha, NAC-alpha, Alpha-NAC.
What is the protein family that this protein belongs to?
Belongs to the NAC-alpha family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic, may also transiently localize to the nucleus.
Protein: RL35_BARQU
Sequence: MPKMKTKSSAKKRFKITASGKVKVAAAGKRHGMIKRSNKFIRDARGTMVLSDQDAKKVIQYYLPNGF
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: NORW_ECO27
Sequence: MSNGIVIIGSGFAARQLVKNIRKQDASIPLTLIAADSMDEYNKPDLSHVISQGQRADDLTRQTAGEFAEQFNLRLFPHTWVTDIDAEAHVVKSQNNQWQYDKLVLATGASAFVPPVPGRELMLTLNSQQEYRACETQLRDARRVLIVGGGLIGSELAMDFCRAGKMVTLIDNAASILASLMPPEVSSRLQHRLTEMGVHLLLKSQLQGLEKTNSGILATLDRQRSIEVDTVIAATGLRPETALARRAGLTINRGVCVDSYLQTSNADIYALGDCAEINGQVLPFLQPIQLSAMVLAKNLLGNNTPLKLPAMLVKIKTPELPLHLAGETQRQDLRWQINTERQGMVARGVDDADQLRAFVVSEDRMKEAFGLLKTLSM
What is the function of this protein?
One of at least two accessory proteins for anaerobic nitric oxide (NO) reductase.  Reduces the rubredoxin moiety of NO reductase.
What are the official names of this protein?
Nitric oxide reductase FlRd-NAD(+) reductase, Flavorubredoxin reductase, FlRd-reductase, FlavoRb reductase.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGD_ECO57
Sequence: MAIEQTAITRATFDEVILPIYAPAEFIPVKGQGSRIWDQQGKEYVDFAGGIAVTALGHCHPALVNALKTQGETLWHISNVFTNEPALRLGRKLIEATFAERVVFMNSGTEANETAFKLARHYACVRHSPFKTKIIAFHNAFHGRSLFTVSVGGQPKYSDGFGPKPSDIIHVPFNDLHAVKAVMDDHTCAVVVEPIQGEGGVTAATPEFLQGLRELCDQHQALLVFDEVQCGMGRTGDLFAYMHYGVTPDILTSAKALGGGFPISAMLTTAEIASAFHPGSHGSTYGGNPLACAVAGAAFDIINTPEVLEGIQAKRQRFVDHLQKIDQQYDVFSDIRGMGLLIGAELKPQYKGQARDFLYAGAEAGVMVLNAGPDVMRFAPSLVVEDADIDEGMQRFAHAVAKVVGA
What is the function of this protein?
Involved in both the arginine and lysine biosynthetic pathways.
What are the official names of this protein?
Acetylornithine/succinyldiaminopimelate aminotransferase, ACOAT, DapATase, Succinyldiaminopimelate transferase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRC_PSEPW
Sequence: MSQVFDASAFLATCSARPGVYRMFDSETRLLYVGKAKNLKKRLASYFRKTGLAPKTAALVGRIAQVETTITANETEALLLEQNLIKQWRPPYNILLRDDKSYPYVFLSDGQFPRLGIHRGAKKAKGRYFGPYPSAGAIRESLSLLQKAFSVRQCEDSYYANRTRPCLQYQIKRCKGPCVGLVDAEEYAEDVRHSVMFLEGRSQQLGNELNAEMEKAAMALNFEKAAELRDQIALLRRVQDQQYMEGGSGDVDVVAAFVNPGGACVHLISVRGGRVLGSKNFFPQVGIEEEVAEVMAAFLSQYYLGNAERELPGELIVNVVHEDFAAISEALQTLRGRELTISHRVRGTRARWQQLAVTNAEQALNARLANRQHMAARFEALAEVLGLDEVPQRLECYDISHSSGEATVASCVVFGPEGPLKSDYRRFNIEGVTAGDDYAAMHQALTRRYGRIKDGEGKLPDVLLVDGGKGQLNMAREVMQELAFTDLTLLGVAKGVTRKAGFETLYLNDVAHEFTLKGDNPALHLIQQIRDEAHRFAITGHRARRGKARRVSSLEDVAGVGPKRRRDLLKHFGGLQELNRASIDEIAKAPGISKKLAESIYASLHSE
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBP1_YEAST
Sequence: MEPIDDILFEVTDAFKTQKEDLLELVTLIDIYGEQVNQEGSYEEKTRFIETLNTLLEDNPSTTGEIGWDLPKGLLKFLSKDNVDVNGRLGTNMIVQGVMKCFYAISIQGEPKKCLITGLELLSSLCSKDFSKSDQQNKEDFVDKKANTLPPEGVIENSSNRKDFPSYGESKSSNEFFLKLKSYILFEFIGASLKRISTLFPSKYLGAAVSTIEKFVYSHADTFEDALFLLRRVYTFCRNYIPPDPPKDIQLNEDFTREMFDKVVEEESELQVRLLRRLCTFGISTPIKTVTTNADVKYYCALNQQKFELSAYYTEYLELFCRYYQMAFSLDVDIEGEFQNVIKECRIIYKSVPQEISAVNDEAKLVLERMVYKLAYTFEVQKAAKEKNVGLDYNGVILFSGIHYLETNQHLVKEMNITDAIYLYLRFTTPSLYSKVYYNVAVESVSRYWLWYAITTEPLEDVKKELKNLSVFVTKTLLHVLLQKNCIQVNQQLRMITFTLLTRLLCLIPEKVAFEFILDVLKTSPLPLAKTSVLCVFKDLSRRRISTKDNDSETDLIVEKLSKLKVNDSNKAQQSNIRHYIQLDSSKMKAVHDCCLQTIQDSFTADAKKSDILLLLTYLNIFIVLKKTWDEDLLKIVCSKIDSNLKSVEPDKLPKYKEIVDKNESLNDYFTGIK
What is the function of this protein?
Involved in oxidative stress response and redox homeostasis.  Required for hydrogen peroxide-induced oxidation and nuclear localization (activation) of YAP1.  Functions probably in concert with HYP1/GPX3, the actual YAP1 modifying enzyme.  YBP1 is not required for HYP1/GPX3-independent, diamide-induced oxidation of YAP1.
What are the official names of this protein?
YAP1-binding protein 1, Activator of YAP1.
What is the protein family that this protein belongs to?
Belongs to the YBP1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_BORHD
Sequence: MINYFELSLKNLGVSFTSESIDKLKFYIKRVLLFGSRFNLVSKNDLRFDAVLLHALDSVVGFPIIKDNNPHQVLDVGSGAGFPGIILAIFDNSRKYVLLERSNKKVTFLRMMSLELGLDNVKVLERDVADEKDKYEFITIRAFRDIREYASILRLILKNGGLIMAYKGRFDKIKFEISHIESLFSKIEIKESAISDAKERNFLLLYK
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EXBD_ECOL6
Sequence: MAMHLNENLDDNGEMHDINVTPFIDVMLVLLIIFMVAAPLATVDVKVNLPASTSTPQPRPEKPVYLSVKADNSMFIGNDPVTDETMITALNALTEGKKDTTIFFRADKTVDYETLMKVMDTLHQAGYLKIGLVGEETAKAK
What is the function of this protein?
Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
What are the official names of this protein?
Biopolymer transport protein ExbD.
What is the protein family that this protein belongs to?
Belongs to the ExbD/TolR family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: KBAZ_ESCF3
Sequence: MKHLTEMVRRHKEGKTNGIYAVCSAHPLVLEAAIRYACANQTPLLIEATSNQVDQFGGYTGMTPADFRGFVCQLAESLNFPQDALILGGDHLGPNRWQNLPAAQAMANADDLIKSYVAAGFKKIHLDCSMSCQDDPVPLTDDIVAERAARLAKVAEETCREHFGEADLVYVIGTEVPVPGGAHETLSELAVTTPDAARATLEAHRHAFEKQGLSAIWPRIIALVVQPGVEFDHTNVIDYQPVKATALSQMVENYETLIFEAHSTDYQTPQSLRQLVIDHFAILKVGPALTFALREALFSLAAIEEELVPAKACSGLRQVLENVMLDRPEYWQSHYHGDGNARRLARGYSYSDRVRYYWPDSQIDDAFAHLVRNLADSPIPLPLISQYLPLQYVKVRSGELQPTPRELIINHIQDILAQYRTACEGQ
What is the function of this protein?
Component of the tagatose-1,6-bisphosphate aldolase KbaYZ that is required for full activity and stability of the Y subunit.  Could have a chaperone-like function for the proper and stable folding of KbaY.  When expressed alone, KbaZ does not show any aldolase activity.
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit KbaZ.
What is the protein family that this protein belongs to?
Belongs to the GatZ/KbaZ family. KbaZ subfamily.
Protein: ALR_BRUME
Sequence: MSLPFSQDERDLAAGGILTIDLAALRHNYSAIATRIAPTRTAAVVKADAYGLGASRVAPAFYEAGCRDFFVAHLGEAVALKPFLKPDATLYVLNGLQPGTEAACAREGILPVLNSLEQVENWAALATRLGKKLPALLQFDTGMSRLGLSAKEFDRLLENVTLLSRIDIKFAISHLANGDEPGNAVNARQLAKMTALLARLPKLPAALANSGGTFLGKTYYFDLARPGIALYGIDPERQHDFSDKVAHENKKPKHSILPVLTLSARVIQVRDVDKGATVGYGGTYVANGPMRIATIAVGYADGLFRSLSNKGAAFFGDTRLPIIGRVSMDSITLDVTSLPEGTLKLGSLVELIGPHQRLEDVARDCDTIPYEILTALGNRYARVYVYVNGGGTSTTA
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: CFMA_ARTBC
Sequence: MKASVIVSVALGASMCLATTLAELPACSQACLQSMLGKAAELGCPPHDPGCLCSHPDFTNGLRDCTKEACPGENIEKVVEEGQKACKDMGGAPGSSTGAPTTGTGSGTATGTPTSGSGSETTAPPTSGSGSAPAPTSGGHSTPYTTIPAGPTVITSGTNVITTSRPATTLYTEVSGSQSGSESGSSTGSGSESTSGPEPTSATSSEGGSSPSSTEGSGGSGGSGGSETSGSGNGPSPTPSQGMAPKATGLGVAGAIGLVALLAL
What is the function of this protein?
GPI-anchored cell wall protein involved in stabilizing the cell wall (By similarity).
What are the official names of this protein?
GPI-anchored hemophore ARB_01545, GPI-anchored CFEM domain protein ARB_01545.
What is the protein family that this protein belongs to?
Belongs to the RBT5 family.
What are the subcellular locations of this protein?
Secreted. Secreted, cell wall. Cell membrane; Lipid-anchor, GPI-anchor. Note=Found anchored in the cell membrane as well as a covalently-linked GPI-modified cell wall protein (GPI-CWP).
Protein: KLD8A_MOUSE
Sequence: MEVPNVKDFQWKRLAPLPSRRVYCSLLETGGQVYAIGGCDDNGVPMDCFEVYSPEADQWTSLPSLPTARAGVAITALGKRIMVIGGVGTNQLPVKVVEMYNIDEGKWKKRSVLREAAMGISVTAKDYRVYAAGGMGLDLRPHNYLQHYDMLKDMWVSLAPMPTPRYAATSFLRGSKIYVLGGRQSKYAVNAFEVFDIESRSWTKFPNIPCKRAFSSFVTLDNHLYSLGGLRQGRLYRQPKFLRTMDVFDMEQGGWLKMERSFFLKKRRADFVAGGLSGRVIVAGGLGNQPTVLETAEAFHPEKNKWEALPPMPTPRCACSSIVFKNCLLAVGGVSQGLSDAVEALFVSDS
What are the official names of this protein?
Kelch domain-containing protein 8A.
Protein: HCP_SHIF8
Sequence: MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIAALQGLSAWAVKAREYGIINHDVDSFAPRAFFSTLTNVNFDSPRIVGYAREAIALREALKAQCLAVDANARVDNPMADLQLVSDDLGELQRQAAEFTPNKDKAAIGENILGLRLLCLYGLKGAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECSMEIGQMNFKVMSILDAGETGKYGHPTPTQVNVKATAGKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLPAHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIIDPTVGAYDDRIWTRSIVGWPGVRHLDGEDFSAVIAQAQQMAGFPYSEIPHLITVGFGRQTLLGAADTLIDLVSREKLRHIFLLGGCDGARGERHYFTDFATSVPDDCLILTLACGKYRFNKLEFGDIEGLPRLVDAGQCNDAYSAIILAVTLAEKLGCGVNDLPLSLVLSWFEQKAIVILLTLLSLGVKNIVTGPTAPGFLTPDLLAVLNEKFGLRSITTVEEDMKQLLNA
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BDSB_ANEVI
Sequence: MNKALFLCLVVLCAAVVFAAEDLQKAKHAPFKRGAAGAAPCFCPDKVDRGDLWMFRGDCPGGYGYTSDCYVWPNICCYPH
What is the function of this protein?
Blocks Kv3 voltage-gated potassium channels.  Reduces blood pressure.
What are the official names of this protein?
Kappa-actitoxin-Avd4i, Kappa-AITX-Avd4i, Antihypertensive protein BDS-11, Antihypertensive protein BDS-9, Blood depressing substance 11, BDS-11, Blood depressing substance 9, BDS-9, Kappa-actitoxin-Avd4k, Kappa-AITX-Avd4k.
What is the protein family that this protein belongs to?
Belongs to the sea anemone type 3 (BDS) potassium channel toxin family.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: LUXS_NEIMF
Sequence: MPLLDSFKVDHTRMHAPAVRVAKTMTTPKGDTITVFDLRFCIPNKEILPEKGIHTLEHLFAGFMRDHLNGNGVEIIDISPMGCRTGFYMSLIGTPSEQQVADAWLASMQDVGNVKDQSKIPELNEYQCGTYQMHSLAEAQQIAQNVLARKVAVNKNEELTLDEGLLNA
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: LIPB_PYRCJ
Sequence: MRGLDLGLLDYVSAWRMMKILHREVASGGDDAFILVEHPHVITVGKHGRTNNVVKWELFVYVVERGGDATYHGPGQLVAYPVVKLRWPLSRYLWMLEEAVIRSLRPLGVEAGRVEKHRGVWVGGKKVASIGIAVEGGVAYHGVAVNVSTDLSYFYHINPCGLHPSAITSLNQLGVEISLEEYKGLFVEAFEEVFEAKVVWVDPAPYLAAAAQLRASPTLLSAPIEAST
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Probable octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURL_NOCFA
Sequence: MTPQVDTVSAAAATPDVAQPYKELGLKDDEYARIKEILGRRPTDAELAMYSVMWSEHCSYKSSKVHLRYFGETTTEEMRKSMLAGIGENAGVVDVGDGWAVTFKVESHNHPSYVEPYQGAATGVGGIVRDIMAMGARPVAVMDQLRFGAADHPDTRRVVDGVVRGIGGYGNSLGLPNVGGETVFDASYQGNPLVNALCAGVMRVEDLHLAFASGTGNKIILFGARTGLDGIGGVSVLASDTFSGDESGAGRKKLPSVQVGDPFTEKVLIECCLELYAAKLVVGIQDLGGAGLSCATSELAAAGDGGMRIELDKVPLRAADMTPAEILSSESQERMCAVVTPENVEAFMAVCRKWDVLATVIGEVTDGDRLVVTWHGETVVDVPPRTVAHEGPVYERPVQRPDYQDALIADTPDTLPRPATADELRETLLRMISSPQLCSRKWITEQYDRYVRGNTVLAEDADAGVIRIDEQTGRGIALATDASGRYTKLDPYAGAQLALAEAFRNVASTGATPKAVTNCLNFGSPEDPGVMWQFQQAVRGLADGCVALGIPVTGGNVSFYNQTGQDAILPTPVVGVLGVIDDVHRRIPTGIGLEPGETLILLGDTRDEFGGSIWAQVVHDHLGGVPPKVDFAREQLLAEVLTAGSRDGMISAAHDLSEGGLAQAVVEAALAGETGCRILLPEDADPFVTLFSESAGRVLVAVPRSEETRFTRMCEARQLPWVRIGVVDQGSDALEVQGHFSIPLTELRAAFEGTLPKLFGAETA
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1467_CLOBK
Sequence: MSGHSKWHNIQAKKGKADAKRGKIFTKIGKEIVVAVKQGGPSADSNPRLRDVIAKAKANNMPNDTIERSIKKASGELNAVDYETITYEGYGPAGIAVLVDVLTDNKNRSAGNVRYAFTKQGGNMGSTGCVSFMFQSKGQIVIEKKDGLDEDELMMMALDAGAEDFESEDEVYVVATSQEDFGTVREALEAEGLEFLEAEIKMVPDTYTAIDEDTATKFQKMLDVLEDDDDVQNVYHNAEFPEGWEE
What are the official names of this protein?
Probable transcriptional regulatory protein CLD_1467.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_DESDA
Sequence: MFAKLEGLEKKYLELEEALAQPDVFNDQDQYRKLTKAHADLSDVVELFRRHRAVSEELAENRLLLHDEDPEIRAMAQEEVHRGEAELPNLEHELKVMLLPSDPLDEKNTILEIRAGTGGEEAALFAADLFRMYTRYAELKNWKVEIMSESPSENGGYKEIICLIAGDRVYSHLKFEAGTHRVQRVPATEAQGRIHTSAATVAVMPEAEEVDVEIRPEDLRIDIYRASGAGGQHVNKTESAVRITHLPTNTVVTCQDERSQHKNKARAMKVLASRILAAERERQSSELSADRKAQVGSGDRSERIRTYNFPQGRCTDHRINLTLYSLDRIMEGELESLVEALGTAAQAEALKAQASE
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAA_SPICI
Sequence: MNTKELWIEVKEILSRDESVSPEIYNYYISDTNLYTVSDNNCLITTKSEIAIGVFEAGLNEKIKNILKKLTGIQYNISFELEKNINKQASVISKIDTLTENNNLAYYENYTFENFVRGDSNHEAMQAALAVALDLGKKWNPLFIYGDSGLGKTHLLHAIENKVNEIYKTNNRVKYLKADEFGKIAMDILNQGHEIIEAFKTSYDIYDCLLIDDIQLLAKRNKTNELFFHIFNSYIEKNKQIVITSDKYPDDLGGFEARIISRFSYGLSIGLDSPDFETALKILEQKLKHQNNLGLFSEESLEFIALNFNSDVRKLEGAIKRLLFLAVMNKKPNEIITLADVEKAFKNAPLQNNEKITPKKIKQIVADSYNITIKAMMSKSRVSNVMQARQLAMYFCRTLLDEPFTRIGTEFGGKDHTTVMNSVKKVEAHISTNKEFKHLVNAIRRKIEGR
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids (By similarity).
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAA_STRA3
Sequence: MTDISILNDIQKIIVLDYGSQYNQLIARRIREFGVFSELKSHKITADEIRDINPIGIVLSGGPNSVYADGAFGIDEEIFELGIPILGICYGMQLITHKLGGKVLPAGEAGHREYGQSALRLRSESALFAGTPQEQLVLMSHGDAVTEIPEGFHLVGDSVDCPFAAMENTEKQFYGIQFHPEVRHSVYGNDILKNFAVNICGARGDWSMDNFIDMEIAKIRETVGDRKVLLGLSGGVDSSVVGVLLQRAIGDQLTCIFVDHGLLRKNEGDQVMDMLGGKFGLNIIRVDASKRFLDLLSGVEDPERKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGTALGMPDEVVWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDVWQYFTVNTGVRSVGVMGDGRTYDYTIAIRAITSIDGMTADFAQLPWDVLKKISTRIVNEVDHVNRIVYDITSKPPATVEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.