PharMolix/UniProtQA huggingface dataset:
Protein: COBT_VIBCH
Sequence: MLDRSFSAEIQQRIDQKTKPLGALGQLERVAHHLALIQSQNQDQAVTQLAIHQPTVLVFAADHGIAAQGVSIAPSAVTEQMVQNFLAGGAAINCFCRTEHAAMRVIDCGILRAQPAHADLIEQRLGAGTHNLAEQAAMSSEQVQEGIALGKALIHREVESGCNLLMFGEMGIGNTSSAAAILAALSGLPIEVCVGRGTGITDEQYQRKRALVTQGVERCLGAAPQDVLQQVGGFEIVQMVGAFMGAYEKQTPVLVDGFIVTVAAYVATLIEPNVRDFLLFAHCSQETGHRAVLEMLAAEPLLDLGLRLGEGTGAVLALGLVRAAVEFYNHMASFADAGVTV
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: VPS33_ARATH
Sequence: MAQIPSLENAPLNLKSIRDKSERELVNLLKDVRGTKCLVIDPKLSGSVSLIIPTSKLKELGLELRHLTAEPVQTECTKVVYLVRSQLSFMKFIASHIQNDIAKAIQRDYYVYFVPRRSVACEKILEQEKVHNLVTVKEFPLYMVPLDEDVISFELELSEKDCLVDGDVSSLWHIAKAIHELEFSFGVISKMRAKGKASVRVADILNRMQVEEPVNSNDVGRPEVDTLILLDREVDMVTPMCSQLTYEGLIDEILHISNGAVEVDSSVMGAQQEGKKMKVPLNSSDKLFKETRDLNFEVVVQVLRQKAMTMKEDYTEINSTQTVSELKDFVKKLNSLPEMTRHIHLAQHLTTFTSKQSFNSQLDMEQTLVEAENYDICYEYIEEMIHKQEPLTNVLRLLVLFSVTNSGLPKKQFDYIRMELLHSYGFEHVVTLNNLEKAGLLKKQEFKSNWLTVKRTLKLIVEDTDTSRPNDIAYVYSGYAPLSIRLIQQAIHSGWRPMEDILKLLPGPHLETKRSGFPSSPSVDSLHGASNGVADGRRSIVLVVFIGGVTFAEISALRYLASKEGMAYDLIVATTKIVNGATLIETFMEKLG
What is the function of this protein?
Involved in regulating membrane fusion at the tonoplast and the prevacuolar compartment.
What are the official names of this protein?
Vacuolar protein-sorting-associated protein 33 homolog, AtVPS33.
What is the protein family that this protein belongs to?
Belongs to the STXBP/unc-18/SEC1 family.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein. Prevacuolar compartment membrane; Peripheral membrane protein.
Protein: TRAF_PENCR
Sequence: MTSGTEQATLNTEENGSDSDHLSKEPIAMPALDWDGPTDSNNPRNFSTPKKVFITACLASLVCISTFGSSVMSPASGQLIHEFGISKELSILATALYVLGFAVGPLLFGPASEVLGRKYPLSVGVFLFAIFSIPIAVAKNVATIFVCRFLCGTFAAAPLAIAGGGLADLWEPLSRGIAVAGFASATFLGPVLGPLVGGFVTKSHLGWRWTQWLSIIFSLVFLAIYFVFCPETYSPIVLARLAKKRGQMPPGGKVDFKQLAKVYMLRPFIMLVQEPILALLTLYMGFIYGFLYLCFEAFPIAFEEHRGWDIGIGSLPFLSITVGVLIGVVIIIVHTMTRMRRKLETVGDAPEERLVPMMIGSILMPAGIFWFAWTSNTSLPWAPQVVSGVFIGCGILLIFLQGMNYIIDVYKVMANSAISINAMFRGLLGAGFPLFASYMFDNLGVPWAMSLLGFLCVALVPVPFLFFIYGERIRKWSKFTAH
What is the function of this protein?
MFS-type transporter; part of the tra gene cluster that produces terrestric acid (PubMed:30811183).  The clavatol biosynthesis cluster cla and the terrestric acid cluster tra are both involved in the production of peniphenones and penilactones (PubMed:30811183).
What are the official names of this protein?
MFS-type transporter traF, Terrestric acid biosynthesis cluster protein F.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. CAR1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PDXJ_PORG3
Sequence: MTRLSVNVNKIATLRNARGGNVPDVLRVALDCERFGAQGITVHPRPDERHIRRSDVYDLKKALTTEFNIEGNPDERFIRLIEEIRPEQVTMVPDAPDVLTSNAGWDVARNYDHLCRLVEQFHAWGIRTSIFIDTDLDNISWAAKTGTDRIELYTEPYAAAYHKDMAAAVQPYVKASAHAHSLGLGINAGHDLNLDNLRYFAERLPYLDEVSIGHALIADALYLGLEETIRQYRDQLAL
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_RICFE
Sequence: MNIIDHFEQENISKLTANKKIPDFEAGDTVKVTVKIIDRSIEKDGKEKLTERFQAYEGVVIAKRNRGITSSFLVRKISHGEGVERRFMTYSPIVHSIDVVKYGVVRRAKLYYLRQRSGKSARIKERHIPIAKTKAAKA
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: PLB1_HUMAN
Sequence: MGLRPGIFLLELLLLLGQGTPQIHTSPRKSTLEGQLWPETLKNSPFPCNPNKLGVNMPSKSVHSLKPSDIKFVAAIGNLEIPPDPGTGDLEKQDWTERPQQVCMGVMTVLSDIIRYFSPSVPMPVCHTGKRVIPHDGAEDLWIQAQELVRNMKENLQLDFQFDWKLINVFFSNASQCYLCPSAQQNGLAAGGVDELMGVLDYLQQEVPRAFVNLVDLSEVAEVSRQYHGTWLSPAPEPCNCSEETTRLAKVVMQWSYQEAWNSLLASSRYSEQESFTVVFQPFFYETTPSLHSEDPRLQDSTTLAWHLWNRMMEPAGEKDEPLSVKHGRPMKCPSQESPYLFSYRNSNYLTRLQKPQDKLEVREGAEIRCPDKDPSDTVPTSVHRLKPADINVIGALGDSLTAGNGAGSTPGNVLDVLTQYRGLSWSVGGDENIGTVTTLANILREFNPSLKGFSVGTGKETSPNAFLNQAVAGGRAEDLPVQARRLVDLMKNDTRIHFQEDWKIITLFIGGNDLCDFCNDLVHYSPQNFTDNIGKALDILHAEVPRAFVNLVTVLEIVNLRELYQEKKVYCPRMILRSLCPCVLKFDDNSTELATLIEFNKKFQEKTHQLIESGRYDTREDFTVVVQPFFENVDMPKTSEGLPDNSFFAPDCFHFSSKSHSRAASALWNNMLEPVGQKTTRHKFENKINITCPNQVQPFLRTYKNSMQGHGTWLPCRDRAPSALHPTSVHALRPADIQVVAALGDSLTAGNGIGSKPDDLPDVTTQYRGLSYSAGGDGSLENVTTLPNILREFNRNLTGYAVGTGDANDTNAFLNQAVPGAKAEDLMSQVQTLMQKMKDDHRVNFHEDWKVITVLIGGSDLCDYCTDSNLYSAANFVHHLRNALDVLHREVPRVLVNLVDFLNPTIMRQVFLGNPDKCPVQQASVLCNCVLTLRENSQELARLEAFSRAYRSSMRELVGSGRYDTQEDFSVVLQPFFQNIQLPVLADGLPDTSFFAPDCIHPNQKFHSQLARALWTNMLEPLGSKTETLDLRAEMPITCPTQNEPFLRTPRNSNYTYPIKPAIENWGSDFLCTEWKASNSVPTSVHQLRPADIKVVAALGDSLTTAVGARPNNSSDLPTSWRGLSWSIGGDGNLETHTTLPNILKKFNPYLLGFSTSTWEGTAGLNVAAEGARARDMPAQAWDLVERMKNSPDINLEKDWKLVTLFIGVNDLCHYCENPEAHLATEYVQHIQQALDILSEELPRAFVNVVEVMELASLYQGQGGKCAMLAAQNNCTCLRHSQSSLEKQELKKVNWNLQHGISSFSYWHQYTQREDFAVVVQPFFQNTLTPLNERGDTDLTFFSEDCFHFSDRGHAEMAIALWNNMLEPVGRKTTSNNFTHSRAKLKCPSPESPYLYTLRNSRLLPDQAEEAPEVLYWAVPVAAGVGLVVGIIGTVVWRCRRGGRREDPPMSLRTVAL
What is the function of this protein?
Calcium-independent membrane-associated phospholipase that catalyzes complete diacylation of phospholipids by hydrolyzing both sn-1 and sn-2 fatty acyl chains attached to the glycerol backbone (phospholipase B activity) (By similarity).  Has dual phospholipase and lysophospholipase activities toward diacylphospholipids.  Preferentially cleaves sn-2 ester bonds over sn-1 bonds.  Acts as a lipase toward glycerolipid substrates (By similarity).  Hydrolyzes fatty acyl chains of diacylglycerols with preference for the sn-2 position and of triacylglycerols with not positional selectivity (By similarity).  May also hydrolyze long chain retinyl esters such as retinyl palmitate (By similarity).  May contribute to digestion of dietary phospholipids, glycerolipids and retinoids, facilitating lipid absorption at the brush border (By similarity).
What are the official names of this protein?
Phospholipase B1, membrane-associated, Phospholipase B, hPLB, Lysophospholipase, Phospholipase A2, Phospholipase B/lipase, PLB/LIP, Triacylglycerol lipase.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family. Phospholipase B1 subfamily.
What are the subcellular locations of this protein?
Apical cell membrane; Single-pass type I membrane protein. Note=Present in the intestinal brush border membranes.
Protein: MTNB_DROVI
Sequence: MALSIFKDLPGEHPRNLIPSLCRQFYHLGWVTGTGGGMSIKYNNEIYIAPSGVQKERMQPEDLFVQDIDGKDLQLPPEIKGLSKSQCTPLFMLAYRHRNAGAVIHTHSQHAVMATLLWPGKTFRCTHLEMIKGVYDEADKRYLRYDEQLVVPIIENTPFERDLADSMYAAMMEYPGCSAVLVRRHGVYVWGQTWEKTKTMSECYDYLFSIAVQMKQAGLDPEKFENALQA
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
What are the official names of this protein?
Probable methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSSA1_ECOLX
Sequence: MKKTIGLILILASFGSHARTEIATKNFPVSTTISKSFFAPEPQIQPSFGKNVGKEGGLLFSVSLTVPENVSQVTVYPVYDEDYGLGRLVNTADDSQSIIYQIVDDKGRKMLKDHGAEVTPNQQITFRALNYTSGDKEIPPGIYNDQVMVGYYVN
What is the function of this protein?
Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0. 5-1. 5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs.
What are the official names of this protein?
CS6 fimbrial subunit A, CS6 pilin.
What are the subcellular locations of this protein?
Fimbrium.
Protein: TRY1_RAT
Sequence: MSALLILALVGAAVAFPLEDDDKIVGGYTCPEHSVPYQVSLNSGYHFCGGSLINDQWVVSAAHCYKSRIQVRLGEHNINVLEGDEQFINAAKIIKHPNYSSWTLNNDIMLIKLSSPVKLNARVAPVALPSACAPAGTQCLISGWGNTLSNGVNNPDLLQCVDAPVLSQADCEAAYPGEITSSMICVGFLEGGKDSCQGDSGGPVVCNGQLQGIVSWGYGCALPDNPGVYTKVCNFVGWIQDTIAAN
What are the official names of this protein?
Serine protease 1, Anionic trypsin I, Anionic trypsin-1, Beta-trypsin, Cationic trypsinogen, Pretrypsinogen I, Trypsin I, Trypsin-1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: KDSB_NITOC
Sequence: MSYKVIIPARYGASRLPGKPLLDLAGKPMLLHVVEKAQKSGAEEVLVATDDRRIEAIVQNHGVQVCMTSVQHDSGTNRLAEAVTQKDYPDQTIIINVQGDEPLLPPSLITQAAEDLKTHPKADIATLCVPIANREELFDPNIVKVVRDIQGYALYFSRAPIPWAREDFAAKTGNRWPTSWSYYRHVGLYAYRASFLRRYPQLPVSPLEQAECLEQLRVLYHGGRIHVAIAGTIPPPGVDTLADLERVRQLLVTQERNHN
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDUI_ECO7I
Sequence: MDVRQSIHSAHAKTLDTQGLRNEFLVEKVFVADEYTMVYSHIDRIIVGGIMPVTKTVSVGGEVGKQLGVSYFLERRELGVINIGGAGTITVDGQCYEIGHRDALYVGKGAKEVVFASIDTATPAKFYYNCAPAHTTYPTKKVTPDEVSPVTLGDNLTSNRRTINKYFVPDVLETCQLSMGLTELAPGNLWNTMPCHTHERRMEVYFYFNMDDDACVFHMMGQPQETRHIVMHNEQAVISPSWSIHSGVGTKAYTFIWGMVGENQVFDDMDHVAVKDLR
What is the function of this protein?
Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.
What are the official names of this protein?
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase, 5-keto-4-deoxyuronate isomerase, DKI isomerase.
What is the protein family that this protein belongs to?
Belongs to the KduI family.
Protein: PUR5_NEIMF
Sequence: MSTSLSYRDAGVDIDAGDQLVENIKPFAKRTMRPEVLGDLGGFGALVEIGKKYKNPVLVSGTDGVGTKLKLAFDWDKHDTVGIDLVAMSVNDILVQGAEPLFFLDYFACGELDVPRATDVIKGIAQGCEESGCALIGGETAEMPGMYPVGEYDLAGFAVGVVEKENVITGRSIGAGDVVLGLASNGAHSNGYSLIRKIIERDNPDLDAEFDNGKTLREAVIAPTRLYVKPILAALEKFTIKGMAHITGGGITENVPRVLPENTVAQIDAKSWELPKLFQWLQKAGNVETQEMYRTFNCGIGMVVIVAAEDADAVQDLLGEQGETVYRLGLIRERQGDEHQTQVA
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THCA_RHOER
Sequence: MTKYARPGTADAIMSFQSRYDNWIGNEWVAPVKGQYFENPTPVTGQNFCDVARSTAEDIELALDAAHAAAPAWGKTSVAERAIILNKIADRMEENLESIALAESWDNGKPIRETLNADIPLAIDHFRYFAGAIRAQEGSLSEINSDTVAYHFHEPLGVVGQIIPWNFPILMAVWKLAPALAAGNAIVLKPAEQTPVSILHLIGIIGDLLPAGVLNIVNGFGVEAGKPLASSPRIKKIAFTGETTTGRLIMQYASQNLIPVTLELGGKSPNVFFSDVLASNDDYQDKALEGFTMFALNQGEVCTAPSRALIQEDIFDEFLAMAAIRTKAVRQGDPLDTDTMIGAQASNDQLEKILSYIEIGKAEGAKVITGGERAELGGDLSGGYYVQPTVFTGNNKMRIFQEIFGPVVSVTSFKDYDEAIEIANDTLYGLGAGVWSRDGGVAYRAGRDIQAGRVWTNTYHQYPAHAAFGGYKQSGIGRENHLMMLSHYQQTKNLLVSYAQKAQGFF
What is the function of this protein?
Degrades all aldehydes potentially generated by N dealkylation of thiocarbamates and may also participate in ethanolamine metabolism and further assimilation of degradation products by thiocarbamate-induced cytochrome P-450.
What are the official names of this protein?
EPTC-inducible aldehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: RS5_BRUC2
Sequence: MAQRERNREERGREERDSEFVDKLVHINRVAKVVKGGRRFGFAALVVVGDQKGRVGFGHGKAREVPEAIRKATEAAKRDMIFVPLRSGRTLHHDVEGRHGAGKVLLRAAPAGKGIIAGGPMRAVFETLGVQDVVAKSLGSSNPYNMVRATFDALKHQMHPKDIAAQRGIKYSTLQARRHDVVGSEE
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: ILVC_LARHH
Sequence: MKVYYDKDADLSIIRDKKVAIIGYGSQGHAHAQNLKESGVDVIVGLRKDGASWKKAEAAGHTVKEVGEAVKTADVVMILLPDETQPDVYRNDIAPNLKKGAALAFAHGFNIHYNQIVPPADIDVIMIAPKGPGHTVRSEFLKGGGVPSLIAVYQDHSGRARDVALSYAAANGGTKGGVIETSFREETETDLFGEQAVLCGGAVELVKAGFETLTEAGYAPEMAYFECLHELKLIVDLMYEGGIANMNYSISNNAEYGEYVTGPEVITAASKEAMKKALYRIQSGEYAKMFILEGKTNYPSMTARRRLTADHPIEKVGAELRAMMPWIAKNKLVDQSKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: SPX3_CHICK
Sequence: MAVPGSSRRQPSNRGLVSHCTHHHIVVFLLTFFSYSLLHASRKTFSNVKVSISSQWTPSCLNSTTFELRPNELWNSNHLFPNAEEATLFLGTLDTIFLFSYAVGLFVSGIVGDRLNLRWVLSFGMCSSALVVFFFGTLTEWLHFYNKWFYCCLWVVNGLLQSTGWPCVVAVMGNWFGKAGRGFVFGLWSACASVGNILGAFLASCVLKYGYEYAFLVTASVQFAGGVIVFCGLLTSPKEVGLPELGADEEGSVEEDANRPLMGDDDADDDEGNYSIQAADTDSQPKAIGFFQACCLPGVVLYSLAYACLKLVNYSFFFWLPFYLSNNFGWKEAEADQLSIWYDVGGIIGGTIQGLISDVLQKRAPVLAISLLFAVGSLFGYSRSPNSKPINAVIMAITGFFIGGPSNMISSAISADLGRQDLVRGSSEALATVTGIVDGTGSIGAAVGQYLVSLIQENLGWMWVFYFFILMASSTILFISPLIVREIRLLLHERRLRMLAE
What is the function of this protein?
Unlike the other SLC37 members, seems to lack glucose-6-phosphate antiporter activity.
What are the official names of this protein?
Sugar phosphate exchanger 3, Solute carrier family 37 member 3.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: TYW4_CANGA
Sequence: MSTQIKREKPIKKQFQKKKFADLAVQGTNNSSIASKRSVELTYLPKLGVGSNAEKLQPGKPYFRYFVPKKIKRSPCINRGYWLRLHAVRSHIESILDSCQENITIINLGCGYDPLPFEMLDPQNPQYSRYSNRLNFIDIDYPDLLNIKSGVIKETPELLSIIGGIDPTETNMIISERYKTIPCDLYDMPAFEALLKSENLGHPNTIKIFIAEVSLAYMKHEKADDIIASCSKFPNSHFIMLEQIIPVGEYEPFSGRMLKHFSKNESPLQTVTKYQTIESQIERFRRYNFTNVNAGDMFQLWNSLSSNVHSKIENIEPFDELEEFHLFCHHYMICHATNNEQFKFNESIKFREPEVLPSLPISGLRIDSIDKIGFSKRFGSSVISKDSIIYTGGASPYRSDEADVINLEECTIETLSNMKLPDARVCHSYDSLMDGKLDILIGGRKAPHQPFNDVFIFEKQTASWEKVATLDYPIYRHATSSLSNDKLLLFGGNFCLKEPFLTITVKSETQIVVRSINCPDSIKSSIGAAMCYNEASNDVIILGGSSNGTEVSDKLIIMSYDDKSETLTVKKEVTNDLFKRYGSKIIHLTDDEYLVVGGTSPDRLFDASNSIITYNSRSDEIKSVRIPDHIWQGDELMLVGFELQKLNGKIIIFGGGATCYGFGSVNNSIYSIEK
What is the function of this protein?
Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway.  Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA.  May methylate the carboxyl group of leucine residues to form alpha-leucine ester residues (By similarity).
What are the official names of this protein?
tRNA wybutosine-synthesizing protein 4, tRNA-yW synthesizing protein 4, Leucine carboxyl methyltransferase 2, tRNA(Phe) (7-(3-amino-3-(methoxycarbonyl)propyl)wyosine(37)-N)-methoxycarbonyltransferase, tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. LCMT family.
Protein: BTUD_ECOL6
Sequence: MSIVMQLQDVAESTRLGPLSGEVRAGEILHLVGPNGAGKSTLLARMAGMTSGKGSIQFAGQPLEAWSATKLALHRAYLSQQQTPPFAMPVWHYLTLHQHDKTRTELLNDVAGALALDDKLGRSTNQLSGGEWQRVRLAAVVLQITPQANPAGQLLLLDEPMNSLDVAQQSALDKILSALCQQGLAIVMSSHDLNHTLRHAHRAWLLKGGKMLASGRREEVLTPANLAQAYGMNFRRLDIEGHRMLISTI
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Vitamin B12 import ATP-binding protein BtuD, Vitamin B12-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Vitamin B12 importer (TC 3.A.1.13.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CPFR6_XENRU
Sequence: GLGSVLGKILKMGANLLGGAPKQ
What is the function of this protein?
Antimicrobial peptide.
What are the official names of this protein?
Caerulein precursor fragment R6, CPF-R6.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPE_POPEU
Sequence: QIIEANLALRR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, chloroplastic, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: Y4NK_SINFN
Sequence: MRPSVLVQTSSIVSSALVSSAIGYAIGWPVSKYFDSNTTMRLLLSPVIGLGIFGAVAVSIFHFLPITAINLMLIVLGLSAVAFWLSKGTIDPLLRSPASPGFCWFTVAFLLCLLPAFEIIPQHYGGSVGVGHPIWDHAKIAIVNEIAQNGLPPANPFHSEAGSPNTLIYYYVWHFIAACSSVITGATGWEADIALTGMTALFSTFVVTWLAVARSRSAYAAWWSLPLLFVGSLKPAVRFVFGKWLEKWMAPEHGLQTWIIQAPWVPQHVFSGTLALIAIMAYLRILYSNAGRNMALAVFMGAILASAYGSSMWAGSLSLLLILPLVGALSVSHVLKVKRLLEVLISLSVTVVITLLCAAVLIREQSAILHTRKVVEFWVFPIFAGDYWFLDIPGFWLVLVFLEFGIIYLSFLIWSFARPSDDSKRYAHIDCALTVSVLAPLFCTQILHSVIMYNDLGWRVLIPSMLVMTALTSGLFSTTIGKGTLVGRLTTITAIILLAPSILVGAKSVYSNTFKFQVEGPDSEEGTAFKASPEMWKAVREVTPPNEAVANNPLDLASVTYTPANISWAILSQRRHCGTTLDFLRAYAAQLTPKKASEIYNFFVRAFAGLATEDHLRIMKEKYRCRTLVVTSRDGLWGKPVLDNNSVYKLVSEKKGKWRIYR
What are the official names of this protein?
Uncharacterized protein y4nK.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: O5AL1_HUMAN
Sequence: MCALKGFLEENFYTYSVAKGNHSTVYEFILLGLTDNAELQVTLFGIFLVVYLASFMGNFGLIMLIQISPQLHTPMYFFLSHLAFVDFSFTSSVAPNTLVNFLCEVKSITFYACAIQVCCFITFVVCELYLLSIMAYDRYVAICNPLLYVILIPRKLCIKLIASTYVYGFTVGLVQTVATSYLSFCDSNVINHFYHDDVPLVALACSDTHVKELMLLIIAGFNTLCSLVIVLISYGFIFFAILRIHSAEGRQKAFSTSASHLTSITIFYGTIIFMYPQPKSSHSLNMDKVASVFNVVVIPTLNPLIYSLRNQEVKNALKRIIEKLCLAVK
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 5AL1, Olfactory receptor OR11-184.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: IMM7_ECOLX
Sequence: MELKNSISDYTEAEFVQLLKEIEKENVAATDDVLDVLLEHFVKITEHPDGTDLIYYPSDNRDDSPEGIVKEIKEWRAANGKPGFKQG
What is the function of this protein?
This protein is able to protect a cell, which harbors the plasmid ColE7 encoding colicin E7, against colicin E7, it binds specifically to the DNase-type colicin and inhibits its bactericidal activity.  Dimeric ImmE7 may possess a RNase activity that cleaves its own mRNA at a specific site and thus autoregulates translational expression of the downstream ceiE7 gene as well as degradation of the upstream ceaE7 mRNA.
What are the official names of this protein?
Colicin-E7 immunity protein, ImmE7, Microcin-E7 immunity protein.
What is the protein family that this protein belongs to?
Belongs to the colicins ColE2/ColE8/ColE9 and pyocins S1/S2 family.
Protein: MURC_STRT1
Sequence: MQGETMSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGLEQAGIPILPFDEKNITEDVELIAGNAFREDNNVEIAYAIKNGYKFKRYHEFLGHFMNQFTSFGVAGAHGKTSTTGLLSHSMKNITDTSYLIGDGTGRGSANAQYFVFEADEYERHFMPYHPAYSIITNIDFDHPDYFTSIDDVFSAFDDYAKQVQKGLFVYGEDSNLRKITSNAPIYYYGFEENDDFMATDIIRTTTGSNFKVKHDGQIIGEFHVPAYGRHNILNATAVIANLYVAGFDMALVAEHLKTFSGVKRRFTEKIISDTVIIDDFAHHPTEIIATLDAARQKYPSKEIVAIFQPHTFTRTIALLDDFAEALNEADAVYLAQIYGSAREVDHGDVKVEDLAAKINKPAKVVTVENVSPLLDHDNAIYVFMGAGDIQLYERSFEELLASLQTHM
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F74A3_HUMAN
Sequence: MWRELRGCPGGDVETAQRLSRRRRGKSSEAVPEKTWRAQRMSQTRESSEAVPEKTWREFRGCPGEDVERAQKLRDCPGEDMETAQTLSARRRAESSEAVPEKTWRELKGCPQEDVERVQRLSLLLHLAVFLWIIIAINFSNSGVKSQSSTYLPSGKILK
What are the official names of this protein?
Putative protein FAM74A3.
What is the protein family that this protein belongs to?
Belongs to the FAM74 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: AK1D1_HUMAN
Sequence: MDLSAASHRIPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNKNVRFVELLMWRDHPEYPFHDEY
What is the function of this protein?
Catalyzes the stereospecific NADPH-dependent reduction of the C4-C5 double bond of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure to yield an A/B cis-ring junction.  This cis-configuration is crucial for bile acid biosynthesis and plays important roles in steroid metabolism.  Capable of reducing a broad range of delta-(4)-3-ketosteroids from C18 (such as, 17beta-hydroxyestr-4-en-3-one) to C27 (such as, 7alpha-hydroxycholest-4-en-3-one).
What are the official names of this protein?
Aldo-keto reductase family 1 member D1, 3-oxo-5-beta-steroid 4-dehydrogenase, Delta(4)-3-ketosteroid 5-beta-reductase, Delta(4)-3-oxosteroid 5-beta-reductase.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMB_NITEC
Sequence: MSSHPPIRSYVLRQGYFSHAQRHAYESLLPRYGIPFSENPIDLDSIFGRTAPKILEIGSGMGETTVEIAAQHPEKDFVAIEVHAPGIGSLLDRIEKHGLTNLRIIPHDAKLVLQHMLTGESLDGIHIFFPDPWPKARHHKRRLIQSDFVSLLCNRLKPGGYLHIATDWEDYAIHSLHVLSSEQRLINTAADYAPRPAYRPLTKFEQRGMKLGHTIRDLIFTKAA
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.