PharMolix/UniProtQA huggingface dataset:
Protein: UBIE_ECOLI
Sequence: MVDKSQETTHFGFQTVAKEQKADMVAHVFHSVASKYDVMNDLMSFGIHRLWKRFTIDCSGVRRGQTVLDLAGGTGDLTAKFSRLVGETGKVVLADINESMLKMGREKLRNIGVIGNVEYVQANAEALPFPDNTFDCITISFGLRNVTDKDKALRSMYRVLKPGGRLLVLEFSKPIIEPLSKAYDAYSFHVLPRIGSLVANDADSYRYLAESIRMHPDQDTLKAMMQDAGFESVDYYNLTAGVVALHRGYKF
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (PubMed:9045837).  In vitro, can use demethylphylloquinol, an intermediate in the biosynthesis of phylloquinone (vitamin K1) in plants and cyanobacteria (PubMed:26023160).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEP4_ECOLI
Sequence: MTMLLPLFILVGFIADYFVNAIAYHLSPLEDKTALTFRQVLVHFRQKKYAWHDTVPLILCVAAAIACALAPFTPIVTGALFLYFCFVLTLSVIDFRTQLLPDKLTLPLLWLGLVFNAQYGLIDLHDAVYGAVAGYGVLWCVYWGVWLVCHKEGLGYGDFKLLAAAGAWCGWQTLPMILLIASLGGIGYAIVSQLLQRRTITTIAFGPWLALGSMINLGYLAWISY
What is the function of this protein?
Plays a role in type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.  Substrates include proteins required for biogenesis of the type II general secretory apparatus.
What are the official names of this protein?
Prepilin leader peptidase/N-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the peptidase A24 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: APG_ORYSJ
Sequence: MLRGNDTGSDLAELLWDNGAPAPLRPPPPPPFQPFTCSAAATTSPPAHDYLFIKNLMRGGGAANHHHHDDDDDDDDDVPWLHYHPVVDDDDDADADTAPLPPDYCAALLSGLSDHLPPPAAAASRVDPDPCSSSHGAVVPSTSAAAAKQARTSGGGGGGVMNFTFFSRPLQQRPSGGETASASASAAATSTVPVESTVVQAATNRLRSTPLFSDQRMAWLHPPKPSPRAAAPPPPPPLAPTTRHRLDTAAATATVAQRLPPSEARAPDAPPPAATATATTSSVCSGNGDRRQLNWRDSHNNQSAEWSASQDELDLDDELAGVHRRSAARSSKRSRTAEVHNLSERRRRDRINEKMRALQELIPNCNKIDKASMLEEAIEYLKTLQLQVQMMSMGTGMFVPPMMLPAAAAAMQHHHMQMQQMAGPMAAAAHFPHLGAAAAMGLAGFGMPAAAQFPCPMFPAAPPMSMFAPPPPPPPFPHAAATAVEQTPSPPGAADAGNAPAVKQA
What is the function of this protein?
Atypical bHLH transcription factor that acts as negative regulator of grain size.  Binds the transcription factor ILI6 and forms a heterodimer of antagonistic bHLH transcription factors that regulates grain length and weight by controlling cell elongation in lemma and palea.  May be involved in the control of lamina inclination through brassinosteroid signaling pathway.
What are the official names of this protein?
Transcription factor APG, Basic helix-loop-helix protein 106, OsbHLH106, Protein ANTAGONIST OF PGL1, bHLH transcription factor bHLH106.
What is the protein family that this protein belongs to?
Belongs to the bHLH protein family.
Protein: RLMI_YERPB
Sequence: MTVRLILAKGREKSLLRRHPWIFSGAVQRLEGDALSGETIDILDSQGKWLARAAYSPESQILARVWTFQQDEVIDCAFFIRRLQQAQNWRDWLAQRDGLNGYRLIAGESDGLPGITIDRFQNFLVLQLLSAGAEYQRETLVSALQHCYPECSIYDRSDVSVRKKEGLPLTQGLICGEMPPALLPISENGMQLFVDIQQGHKTGFYLDQRDSRLAARNYANGRRVLNCFSYTGAFAVAALMGNCQQVISVDTSQSVLDIAKQNIELNQLDLSKTEFVRDDVFQLLRSYRAQGEKFDLIIMDPPKFVENKSQLASACRGYKDINMLAIQLLRPGGILLSFSCSGLMPVDLFQKILADAALDAGHDIQFIEQFRQAADHPVIAAYPEGLYLKGFACRVM
What is the function of this protein?
Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase I, 23S rRNA m5C1962 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RlmI.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UCRIL_HUMAN
Sequence: MQQIYTVKEIRSVAARSGPFAPVLSATSRGVAGALRPLVQATVPATPEQPVLDLKRPFLSRESLSGQAVRRPLVASVGLNVPASVCYSHTDIKVPDFSEYRRLEVLDSTKSSRESTEARKGFSYLVTGVTTVGVAYAAKNAVTQFVSSMSASADVLALAKIEIKLSDIPEGKNMAFKWRGKPLFVRHRTQKEIKQEAAVELSQLRDPQHDLDRVKKPEWVILIGVCTHLGCVPIANAGDFGGYYCPCHGSHYDASGRIRLGPATLNLEVPTYEFTSDDMVIVG
What are the official names of this protein?
Putative cytochrome b-c1 complex subunit Rieske-like protein 1, Ubiquinol-cytochrome c reductase Rieske iron-sulfur subunit pseudogene 1.
What is the protein family that this protein belongs to?
Belongs to the Rieske iron-sulfur protein family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RS11_CAMC5
Sequence: MAKRKIVKKKVVRKSIAKGIVYISATFNNTMVTVTDEMGNAIAWSSAGGLGFKGSKKSTPYAAQQAVEDALNKAKEHGIKEVGIKVQGPGSGRETAVKSVGAVEGIKVTFLKDITPLAHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: MSHB_KRIFD
Sequence: MSELPDRRLLLVHAHPDDETINNGATMARYVAEGAHVTLVTCTLGEEGEVLVPELAHLAADQSDQLGRHRIGELAAAMDELGVTDHRFLGGPGRYRDTGMIYDEQGNAAVPPDTRPDSFWQADLVTAANDLVTVIREVRPQVLVTYDEFGNYGHPDHVQAHRVATYAAALAAARSYREDLGPAWDIPKIYWTAISETAMRSSLRRLRESGDHTTFEGMDPDGPLGPMITPDRFIDCVIPADGYLDRKMNAMKAHATQITVDGPFFALSNNDGNEIFGDEFYRLVKGTAAPGSDGLEHDLFAGL
What is the function of this protein?
Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.
What are the official names of this protein?
1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase, GlcNAc-Ins deacetylase, N-acetyl-1-D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase.
What is the protein family that this protein belongs to?
Belongs to the MshB deacetylase family.
Protein: MACB_RHIME
Sequence: MAPLISLQDVSKTYFNGDIAVEVLHHISLDIEAGEFVAIIGQSGSGKSTLMNILGCLDQPTSGSYFIEGENVSGFDSDELAALRRRTFGFIFQSYNLIPTASARENVEVPAVYAGVSARDRHDRAEALLQSLKLGERIDHRPNQLSGGQQQRVSIARALMNGGRVILADEPTGALDSQSGDEVMRLLRDMNENGHTVIVITHSREVAAQADRLIEISDGHIVADRSKKRRSNRDAAVGLAQRTREGFAAIADVSEAVKMALRALRANLFRTILTLLGIVIGVGSVVAMLAIGTGAQNSVLDRISSMGSDLLVVRPSMANFRGSAGGTNVTLVPADADAITELANVAFAVPEMTSTVTLRRGNIDYQTTANGTVPQFTEAKSWKIGRGEFINRNDMETYAPVAVLGETVVKTLFPEGSDPIGQYVLVNKIPFQVIGVMSGMGASAGGNDQDDVVLVPLTTGSMRLFGQRNIRTITVKVQDASAIDLTQERIQALLNERHRKDDTQITNMSSVREAFTETSNTMKFFLGSVAAISLLVGGIGVMNIMLVSVSERTREIGVRMATGARERDILVQFIVEALVVSAIGGAIGVVAGLSTGYAAKAFGMPVSFTPGPVALAFACAFLTGLLFGYLPARNASRLQPAVALSAD
What is the function of this protein?
Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation.  Confers resistance against macrolides.
What are the official names of this protein?
Macrolide export ATP-binding/permease protein MacB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRMJ_METJA
Sequence: MIIMISVILVNPKYSGNVGSIARVMMNFGFEELRIVGDKSIINNEAYMMAVHAREILDNAKFYNTFDEAIGDLDFVIATSGARGGDRNLKRVPITPKELADKILEVKGNIGIVFGREDDGLRNEEIDKCDLLVSIPTSEKYPIMNLSHAVAVILYEIYTKKVRNKFLDINMREASKEDKELLIRKFNEFIDKNEKIPEHKKELCKIIFKRLVNRAFISGKEAWTLMSAFK
What is the function of this protein?
Catalyzes the formation of 2'O-methylated cytidine (Cm32) at position 32 in tRNA.
What are the official names of this protein?
tRNA (cytidine-2'-O-)-methyltransferase TrmJ, tRNA (cytidine(32)-2'-O)-methyltransferase, tRNA Cm32 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDR1_PETAX
Sequence: MEGGEELFRVSSARLSSSNVWRNSAMDVFSRSSREADDEEALKWAALEKLPTYLRIRRGILTEEEGQSREVDITKLDLVERRNLLERLIKITDEDNEKFLLKLKERIDRVGLDLPTIEVRFEHLSVDAEARVGSRALPTVFNFTVNILEDFLNYLHILPNRKQPLPILHDVSGIIKPGRMTLLLGPPSSGKTTLLLALAGKLDKDLKVSGRVTYNGHDMNEFVAQRSSAYISQYDLHIGEMTVRETLAFSARCQGVGAKYEILAELSRREKEANIKPDPDVDIFMKAAWNEGQEANVVTDYTLKILGLEICADTIVGDEMIPGISGGQRKRLTTGEMMVGPARALFMDEISTGLDSSTTYQIVNSIRQSIHILQGTAVISLLQPAPETYDLFDDIILLSDGQIVYQGPRENVLEFFEYMGFICPERKGVADFLQEVTSRKDQEQYWARREESYKFITVREFSEAFQAFHIGRKLGDELAVPFDKSKSHPAALTTKRYGVSKKELLKACTAREYLLMKRNSFVYIFKMIQLTLMASITMTLFLRTEMHRNTTIDGAVFLGALFYALIMIMFNGFSELALSIMKLPSFYKHRDLLFFPPWAYALPTWILKIPITLVEVAIWVCMTYYVIGFEADVGRFFKQLLLLICVNQMASGLFRLMGALGRNIIVANTFGSFVLLTVLVMGGFVLSRDDVKKWWIWGYWISPMMYAQNAIAVNEFLGKSWAHVPPNSTSTETLGVSFLKSRGIFPDARWYWIGAGALIGYVFLFNFLFAVALAYLNPFGKPQAVLSEETVAERNASKRGEVIELSSLGKSSSEKGNDVRRSASSRSMSSRVGSITAADLSKRRGMILPFEPLSITFDDIRYAVDMPQEMKAQGFTEDRLELLRGVSGAFRPGVLTALMGVSGAGKTTLMDVLAGRKTGGYIDGTISISGYPKQQETFARIAGYCEQTDIHSPHVTVYESLQFSAWLRLPREVDTATRKMFIEEVMELIELIPLRDALVGLPGVNGLSTEQRKRLTVAVELVANPSIIFMDEPTSGLDARAAAIVMRTVRNTVDTGRTVVCTIHQPSIDIFDAFDELLLLKRGGEEIYVGPLGRQSSHLIKYFEGIDGVPKIKDGYNPATWMLEITSVAQEGALGNDFTELYKNSELYRRNKALIKELSVPASCSKDLYFPTKYSQSFFTQCMACFWKQHWSYWRNPPYTAVRIMFTFFIALMFGTIFWDLGSRRERQQDLLNAIGSMYIAVLFLGVQNATTVQPVIAIERTVFYRERAAGMYSAMPYAFGQVMIELPYLFLQTIIYGVIVYAMIGFEWTVAKFFWYLFFMYFTLLYFTLYGMMTVAVTPNHSIAAIISSAFYAVWNLFCGFIVPKTRMPVWWRWYYYICPISWTLYGLIASQFGDIQDRLDTNETVEQFIENFFDFKHDFVGYVALILVGISVLFLFIFAFSIKTFNFQKR
What is the function of this protein?
Cellular strigolactone (SL) transporter required for the exudation of SL from the root to the soil (PubMed:22398443, PubMed:25683808, PubMed:27040840).  The presence of SL in the vicinity of the roots is required for development of symbiotic interactions with arbuscular mycorrhizal fungi (AMF) (PubMed:22398443, PubMed:27040840).  Transports SL in the above ground tissues and is required for the control of shoot branching (PubMed:22398443, PubMed:27040840).  SL regulates plant shoot architecture by inhibiting the outgrowth of axillary buds (PubMed:22398443, PubMed:27040840).  Involved in the regulation of shootward and outward directional strigolactone transport in roots (PubMed:25683808).  Due to its polar localization in root cells, mediates directional shootward strigolactone transport, as well as localized outward directional transport for exudation to the soil (PubMed:25683808).
What are the official names of this protein?
Pleiotropic drug resistance protein 1, PaPDR1, ABC transporter G family PDR1, Strigolactone transporter.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Localizes to the plasma membrane (PubMed:22398443, PubMed:25683808, PubMed:27040840). Exhibits asymmetric localization in different root tissues (PubMed:25683808). In root tips, localizes at the apical membrane of hypodermal cells (PubMed:25683808). In the hypodermal passage cells localizes in the outer-lateral membrane (PubMed:25683808).
Protein: RSMH_ECO7I
Sequence: MMENYKHTTVLLDEAVNGLNIRPDGIYIDGTFGRGGHSRLILSQFGEEGRLLAIDRDPQAIAVAKTIDDPRFSIIHGPFSALGDYVAERDLIGKIDGILLDLGVSSPQLDDAERGFSFMRDGPLDMRMDPTRGQSAAEWLQTAEEADIAWVLKTYGEERFAKRIARAIVERNREQPMTRTKELAEVVAAATPVKDKFKHPATRTFQAVRIWVNSELEEIEQALKSSLNVLAPGGRLSIISFHSLEDRIVKRFMRENSRGPQVPAGLPMTEEQLKKLGGRQLRALGKLMPGEEEVAENPRARSSVLRIAERTNA
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEC63_SCHPO
Sequence: MSSEYKYDEQGIFFPVFLLVGTSCCVLPLTYSTILGPSASKEKKNVRDPFQKYRPKDLKVQRKSIFRLRYIFLILGWLAIGFLSYKIANSRLKLNIWDPYEILGIAKGTSVDDVRRHYKRLSIKFHPDKVRNMVNTTREEVEKHYIEITNAYRALTDDKTRENYALYGTPDVPQHISVGIALPKWISESENSIYILGFYGLVFGIVLPYAVGKWWYGSRTYTRDHVHVDTVDEWFPKMETSLTLDELLSLFASSKELTSLVPNEKNPKEYILKLLFDHLNRKKTNNFNTHQILSQSDVVLNALLSVATAFGFANPVDNVLKLWQHIVQAIPLDAPFPLLQLPHLLMEDVKNLSIRNISSIPQFLSLSEEQTKDYLPNYSKNQLKEMREIANGIPRISVVAAKVLVDDDEYITVGAIANLILDLKCSYGTEVVPEVSTDGTETATKKDEEDAEKYHQSKDVVLGDVETLPYAWAPYFTQHHKTAWWIYVVDPRQNRVIVPPFSITDIPKTLRTFRIPFQVPPVAGTFSFQLHIMSNSYVGEDVISNLTMIVKDTSVLQEQLQEEAVSDLEDNSDIDESANAGKDFSDDENIGSDEEDESEYDPMDTDTSDGE
What is the function of this protein?
Acts as component of the Sec62/63 complex which is involved in SRP-independent post-translational translocation across the endoplasmic reticulum (ER) and functions together with the Sec61 complex and bip1 in a channel-forming translocon complex.  A cycle of assembly and disassembly of Sec62/63 complex from sec61 may govern the activity of the translocon.  sec63 may affect sec61-polypeptide interactions by increasing the affinity of targeting pathways for sec61 and/or by modifying sec61 to allow more efficient polypeptide interaction.  May also be involved in SRP-dependent cotranslational translocation (By similarity).
What are the official names of this protein?
Translocation protein sec63.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus membrane; Multi-pass membrane protein. Nucleus inner membrane; Multi-pass membrane protein.
Protein: NQOR_NITWN
Sequence: MAKVLVLYYSAYGHIEAMANAVADGARQAGATVDVKRVPELVPEAVAKAKYFKLDQAAPLAKVDDLADYDAIVVGTGTRFGRMSSQMASFLDQAGGLWARGALHGKVGGAFSSSATQHGGQETTLFSIITNLLHFGMTIVGLNYGFAGQMGVKEVTGGAPYGATTIADGDGSRPPSENELAGARYQGRMIAETAAKLHG
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: RL20_BORDL
Sequence: MARVKNGIVHVARRKRILKKTKGFWGTKKSNYKKAKDTLRKGMMYATRDRKTRKRDLRSLWIVRISAALTGMGINYSRFFEGLRKLNIKLNRKILSNLAIEDIESFKKIVYEIKN
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: TASL_HUMAN
Sequence: MLSEGYLSGLEYWNDIHWSCASYNEQVAGEKEEETNSVATLSYSSVDETQVRSLYVSCKSSGKFISSVHSRESQHSRSQRVTVLQTNPNPVFESPNLAAVEICRDASRETYLVPSSCKSICKNYNDLQIAGGQVMAINSVTTDFPSESSFEYGPLLKSSEIPLPMEDSISTQPSDFPQKPIQRYSSYWRITSIKEKSSLQMQNPISNAVLNEYLEQKVVELYKQYIMDTVFHDSSPTQILASELIMTSVDQISLQVSREKNLETSKARDIVFSRLLQLMSTEITEISTPSLHISQYSNVNP
What is the function of this protein?
Innate immune adapter that mediates the recruitment and activation of IRF5 downstream of endolysosomal toll-like receptors TLR7, TLR8 and TLR9 (PubMed:32433612).  Following recruitment to endolysosome by SLC15A4 downstream of TLR7, TLR8 and TLR9, specifically recruits IRF5 transcription factor via its pLxIS motif, leading to IRF5 activation and subsequent expression of type I interferons (PubMed:32433612).  Plays a role in the regulation of endolysosomal pH in immune cells such as B-cells, dendritic cells and monocytes (PubMed:31001245).
What are the official names of this protein?
TLR adapter interacting with SLC15A4 on the lysosome.
What are the subcellular locations of this protein?
Lysosome membrane. Endosome membrane. Nucleus. Cytoplasm. Note=Recruited to endolysosome following interaction with SLC15A4 (PubMed:32433612). May colocalize with TLR7 in the endosomal pathway (PubMed:31092820).
Protein: HBD_THETC
Sequence: MQKICVIGAGTMGSGIAQVFAQNGFEVILRDIDMKFVEKGFGTIEKNLQRNVDKGKITADEKNEILSRIRGTTNLEDAKEADFVVEAAIENMDLKKQIFKELDEICKMETILASNTSSLSITEIASATKRPEKVIGMHFFNPVPVMKLVEVIKGLKTSEQTFNVVRELALKVDKTPIEVKEAPGFVVNRILIPMINEAIGILADGVATAEDIDEAMKLGANHPIGPLALSDLIGNDVVLAIMNVLYEEYGDSKYRPHPLLKKMVRGGLLGRKTGKGFFEYK
What are the official names of this protein?
3-hydroxybutyryl-CoA dehydrogenase, Beta-hydroxybutyryl-CoA dehydrogenase, BHBD.
What is the protein family that this protein belongs to?
Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
Protein: DEOC_MYCPI
Sequence: MNYNSLFDHTLLRADASVEEIKQLCDEAVKFNFFSVCVNPSYVPYVKEQLHNSSVKICTVVGFPLGQTSTKQKVYETKIAIKEGADEIDMVLNISEFKENCACVVNEIRKYKKVCKKKILKVIVETALLSENEIEKATLVVIDGGADFIKTSTGFSSRGASIKDIEIMKNVIEKNNSKLKIKASGGIKTLTFVEELIKAGAERIGSSKSVEIIKETLNKN
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPC_BACCQ
Sequence: MGTILDKIVDQKKKEVAALYETYTPVKEKRKTRSLVKALEQFTVIAEVKRASPSKGDINLHVDVRKQVKAYEECGAGAVSVLTDGQFFKGSFYDLQTAREESSIPLLCKDFIIDKIQIDRAYEAGADIILLIVAALTKEKLKELYSYVLEKGLEAIVEVHDEQELEIAIQFNPHVIGINNRNLKTFEVDLSQTEKLGKRLNEEKLLWISESGVHSKEDMIRVKRAGAKGVLVGEALMTSSSIHTFFEDCKVNI
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: GREA_STAAR
Sequence: MENQKQYPMTQEGFEKLERELEELKTVKRPEVVEKIKVARSFGDLSENSEYDAAKDEQGFIEQDIQRIEHMLRNALIIEDTGDNNVVKIGKTVTFVELPGDEEESYQIVGSAESDAFNGKISNESPMAKALIGKGLDDEVRVPLPNGGEMNVKIVNIQ
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: PG053_VAR67
Sequence: MAETKEFKTLYNLFIDSYLQKLAQHSIPTNVTCAIHIGEVIGQFKNCALRITNKCMSNTRLSFTLMVESFIEVISLLPEKDRRAIAEEIGIDLNDVPSAVSKLEKNCNAYAEVNNIIDIQKLNIGECSAPPGQHMLLQIVNTGSAGANCGLQTILKSLNKIYVPPIIENRLPYYDPWFLVGVAIILVIFTVAICSIRRNLALKYRYGTFLYV
What is the function of this protein?
Component of the entry fusion complex (EFC), which consists of 11 proteins.  During cell infection, this complex mediates entry of the virion core into the host cytoplasm by a two-step mechanism consisting of lipid mixing of the viral and cellular membranes and subsequent pore formation.
What are the official names of this protein?
EFC-associated protein OPG053, Protein F9.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG053 family.
Protein: YCAD_SHISS
Sequence: MSTYTRPVMLLLSGLLLLTLAIAVLNTLVPLWLAQEHMSTWQVGVVSSSYFTGNLVGTLLTGYVIKRIGFNRSYYLASFIFAAGCAGLGLMIGFWSWLAWRFVAGVGCAMIWVVVESALMCSGTSRNRGRLLAAYMMVYYVGTFLGQLLVSKVSTELMSVLPWVTGLTLAGILPLLFTRVLNQQAENHDSTSITAMLKLRQARLGVNGCIISGIVLGSLYGLMPLYLNHKGVSNASIGFWMAVLVSAGILGQWPIGRLADKFGRLLVLRVQVFVVILGSIAMLSQAAMAPALFILGAAGFTLYPVAMAWACEKVEHHQLVAMNQALLLSYTVGSLLGPSFTAMLMQNFSDNLLFIMIASVSFIYLLMLLRNAGHTPKPVAHV
What are the official names of this protein?
Uncharacterized MFS-type transporter YcaD.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. YcaD (TC 2.A.1.26) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MSAB2_STRR6
Sequence: MHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYELINQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDKDLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAYPVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEPLFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGPQDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA/MsrB 2.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the MsrB Met sulfoxide reductase family.
Protein: RCEL_ACIMU
Sequence: DFWVGPFYVGFFGVTAAFFIMLGTALIIWGAALGPTWNIWQISIAPPDLSYGLGLAPLAKGGLWQIITVCAIGAFGSWALREVEISRKLGIGLHVPAAFSVAIFAYVTLEVIRPLLMGAWGNGFPYGIMSHLDWVSNTGYAYLNFEYNPMHMVAVTLFFTTTLALALHGSLVLAAINPPAGETVKFAEHEDTFFRDFIGYSIGTLGIHRLGLFLALGAGFASATCILLSGPFWTQGWPSWWGWWLHLPIWQFGGH
What is the function of this protein?
The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis.
What are the official names of this protein?
Reaction center protein L chain, Photosynthetic reaction center L subunit.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS4_BORBU
Sequence: MNRKQIAKGKLVRRFGINIFEQPKYDKILKKKPHPPGMHGKARKAKITEYGKQLIEKQKIKFTYGVSERQLTNTFKEAKKHHGVTGDNLLSILERRIDNVVYRAGFAISRAHARQIVSHGIIILNGRRVTIPSIILRANDQIQIKEKDSLKKLIRSNIEKTSSLRNLPTWIEVNADDLNIKVKHAPSRDEIPTLANEQMVVEYYSKRA
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: MURG_HELPY
Sequence: MKFALTGGGTGGHLSIAKALAIELEKQGIEAIYLGSTYGQDKEWFENSPLFSERYFFNTQGVVNKSFFKKIGSLFLQAKAAFKAKEILKKHQITHTISVGGFSAGPASFASLLNKIPLYIHEQNAIKGSLNRYLSPKAKAVFSSYAFKDKGNHVLTSYPVQNAFFDFARTRTEIKHILFLGGSQGAKAINEFALLNAPKLTKQGIKITHICGPNSYEQVRFFYQELGLLDKIELFAFHNNITEIMHRADLCVSRAGASSVWELCANGLPTIFIPYPFASNNHQYYNVLEFEKENLCYVVPQNELLPKKLFEVIRKLNQKDDQGNKNLTTISNQLQQKIAKDGAKTIIETILSA
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: UTH1_CANAL
Sequence: MKYLTLLTVLSTALATPLQHQHHHHHEHARRAEVTKVVYVNGNGDEVQSQVTENASSGASSGETAETIQTRSSSDVSSSSDSNPVASIASSVASSASSILSNIEGDLSAFSSPSKKFEDGVYDCDSVPVGQGVIGVDWISGLNGGWTTIMNENGDTSLNCKDGYYCSYACQAGMSKTQWPSEQPSNGMSIGGLYCKNGKLYRSNTDNDYLCEWGSKDVNFVSEISEDVAICRTDYPGSENMNIPTLLSAGGKAPCSVVDGDTYFKWQGGKTSTQYYVNNAGVSVEDGCIWGTEGSGVGNWAPVVLGSGTTGGKTYLSLIPNPNNKDKPNYNIKIVGDDVNGDCKYENGQYNGSGSDGCTVTVNSGSAKFVFY
What is the function of this protein?
Cell surface beta-glucosidase involved in cell wall maintenance and cytokinesis.  Plays a role redundant to SUN41.
What are the official names of this protein?
Secreted beta-glucosidase SIM1.
What is the protein family that this protein belongs to?
Belongs to the SUN family.
What are the subcellular locations of this protein?
Secreted, cell wall.