PharMolix/UniProtQA huggingface dataset:
Protein: ICT1_SALSA
Sequence: MATSVAKYFLLSRCSGIIRSVTLQGKLPPVCIRNSQCPSFSYGNRASDNPQDGHVNIPVDRLTVSYSRSSGPGGQHVNKVSTKAEVRFHVYTADWIPEDVRQKIILNNKNRINKAGELLVTSEQSRSQQRNMGDCIQKISDIIAKATEKPHEPSAEDIALRASRLEKRNKERLKQKKLHSAVKQTRRVCFD
What is the function of this protein?
Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit.  Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation.  May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes (By similarity).
What are the official names of this protein?
Peptidyl-tRNA hydrolase ICT1, mitochondrial, Immature colon carcinoma transcript 1 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family. Mitochondrion-specific ribosomal protein mL62 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GRCA_ECOSM
Sequence: MITGIQITKAANDDLLNSFWLLDSEKGEARCIVAKAGFAEDEVVAVSKLGDIEYREVPVEVKPEVRVEGGQHLNVNVLRRETLEDAVKHPEKYPQLTIRVSGYAVRFNSLTPEQQRDVIARTFTESL
What is the function of this protein?
Acts as a radical domain for damaged PFL and possibly other radical proteins.
What are the official names of this protein?
Autonomous glycyl radical cofactor.
Protein: SYH_ENTFA
Sequence: MSYQKPKGTNDILPGTSEKWQFVEETARLIFKDYQYQEIRTPIFEHYEVISRSVGDTTDIVSKEMYDFYDKGDRHVTLRPEGTAPIVRAFVENKLYGPEYTKPYKTYYMGPMFRYERPQAGRLRQFHQIGVEAFGSENPALDVEIMAMALDFFKQLGIQQIKLVINSLGDKETRATYRQALIDYLEPHMAELSEDSQRRLHENPLRVLDSKDKKDKVIVAEAPSILDYLNEPSKAHFEAVTDMLDLLEIPYEIDSNMVRGLDYYTHTIFEIMSEAPKMGAQSTICAGGRYNGLVEELGGPDTPGFGFGMGIERVLLTMEAEEVVIPALSELDAYVVGIGSDTNVAALQLVQSIRNFGFSADRDYMNRKPKAQFKTADKLQAKLVLTIGENELNEGIVNVKSMATREEKAFPLSAIHDSFDEVYDEMMTKMIEE
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYV_RICCK
Sequence: MKAFPKNYNFTENEKKWQRIWQEKQIYAYDPNISKEETYIVDTPPPTVSGQLHIGHVYSYTQTDFIVRFQRMIGKNIFYPMGFDDNGLPTERLVEKQKQIKAYNIGRNKFIQICEEVVASEEEKFRGLLNKIALSVDWSLEYQTISPLSQKISQMSFLDLVKRGEIYRNDQPILWDPVDGTALAQADIKDTENSSLMNYITFKTEQGEPLTIATTRPELLPACVAVFYHPDDRHYKHLAGKFVITPLFKDKVPLLADPLVQQDKGTGLVMCCTFGDQTDITWWKTHNLPLKTIITKKGTIDFPNDIGIDRLKIKEARAKIIDILKEQNLLIKQEEITHIVKCAERSGSPLEILTMPQWFVKTISHKEALLKRANELNWHPKNMKIRLENWINAISWDWCISRQRCFGVPFPVWYSKRVGEEGKILYADIAQLPVDPLRDLPIGYSRDEVEPDLDVMDTWATSSVSPQLSTHGISDDFAINKNRHDKLFPMDLRPQAHEIIRTWAFYTILKAHLHQNTLPWKNIMVSGWCLAEDRSKMSKSKGNVLVPEKLLEQYGSDVIRYWSANSKLGADTAYSEDVMKNGKRLVNKLWNAAKFVSIHLHKLKDQDKKAKLLEVKEIITNEFDKWMINKLVELVNAVTNELQNYEYANAMHLTEKFFLAVFCDNYLEISKTRAYDEDNKNLSGQYSSILTLYHVMQTLLKLFAPFMPHITEELYQILYNDKESIHIKGTFANHDNLHYNIDTKQAEGMLKILDIVRKFKAEKNLSIKAPIKLLKISGIVLSEELAEDLKNVTSAEEIKFEIQDNKIKIDIII
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIE_JANMA
Sequence: MKSNLHGLYLVTPDWDDTRKLLEITELALKGGVSLLQYRHKTADAALRQEQAECLQALCRSYEVPFIINDHIDLCLGINADGIHVGGTDKSVAEVRAIIGPDKILGSSCYGDLALAHAAEAAGASYVAFGGFYPSKVKKYPVTTAPTIVSDWKAQGKVPSCVIGGMTRDNSAPLVANGADMVAAISSVYLAGDPQAAARAFVSLFAK
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: PAL4G_HUMAN
Sequence: MVNSVIFFDITVDGKPLGRISIKQFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTHPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICTAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase A-like 4G, PPIase A-like 4G, Peptidylprolyl cis-trans isomerase A-like 4.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APAH_HAMD5
Sequence: MSNYLIGDVHGCFDELKALLAKVNFDKEKDTLWLTGDLISRGPQSLKVLRYARSLGKALRMVLGNHDLHLLAIHAGMRKNNPKDHLTSLLAAPDVDQLMDWLRQQPLLQIDDDLKLIMTHAGIYPKWDKKTAQTCAQEIEVALRGNRLPLFLDRSHTQTPHSWSPKLKGDARLQFITNALTRMRYCFSDGSLDMTHKEIPEKVQDDLYPWFLLPRLLEPEYAITFGHWSALKGKGTPKNIYALDTGCCWGNELTLLHWEEKRYFIQPAYKCENEF
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: KCNH1_BOVIN
Sequence: MTMAGGRKGLVAPQNTFLENIVRRSNDTNFVLGNAQIVDWPIVYSNDGFCKLSGYHRAEVMQKSSTCSFMYGELTDKDTIEKVRQTFENYEMNSFEILMYKKNRTPVWFFVKIAPIRNEQDKVVLFLCTFSDITAFKQPIEDDSCKGWGKFARLTRALTSSRGVLQQLAPSVQKGENVHKHSRLAEVLQLGSDILPQYKQEAPKTPPHIILHYCVFKTTWDWIILILTFYTAILVPYNVSFKTRQNNVAWLVVDSIVDVIFLVDIVLNFHTTFVGPAGEVISDPKLIRMNYLKTWFVIDLLSCLPYDVINAFENVDEVSAFMGDPGKIGFADQIPPPLEGRESQGISSLFSSLKVVRLLRLGRVARKLDHYIEYGAAVLVLLVCVFGLAAHWMACIWYSIGDYEIFDEDTKTIRNNSWLYQLAMDIGTPYQFNGSGSGKWEGGPSKNSVYISSLYFTMTSLTSVGFGNIAPSTDIEKIFAVAIMMIGSLLYATIFGNVTTIFQQMYANTNRYHEMLNSVRDFLKLYQVPKGLSERVMDYIVSTWSMSRGIDTEKVLQICPKDMRADICVHLNRKVFKEHPAFRLASDGCLRALAMEFQTVHCAPGDLIYHAGESVDSLCFVVSGSLEVIQDDEVVAILGKGDVFGDVFWKEATLAQSCANVRALTYCDLHVIKRDALQKVLEFYTAFSHSFSRNLILTYNLRKRIVFRKISDVKREEEERMKRKNEAPLILPPDHPVRRLFQRFRQQKEARLAAERGGRDLDDLDVEKGSVLTEHSHHGLAKASVVTVRESPATPVAFPAAAAPAGLDHARLQAPGAEGLGPKAGGADCAKRKGWARFKDACGQAEDWSKVSKAESMETLPERTKAAGEATLKKTDSCDSGITKSDLRLDNVGEARSPQDRSPILAEVKHSFYPIPEQTLQAAVLEVKHELKEDIKALSTKMTSIEKQLSEILRILTSRRSSQSPQELFEISRPQSPESERDIFGAS
What is the function of this protein?
Pore-forming (alpha) subunit of a voltage-gated delayed rectifier potassium channel (PubMed:9524140).  Channel properties are modulated by subunit assembly.  Mediates IK(NI) current in myoblasts.  Involved in the regulation of cell proliferation and differentiation, in particular adipogenic and osteogenic differentiation in bone marrow-derived mesenchymal stem cells (MSCs) (By similarity).
What are the official names of this protein?
Potassium voltage-gated channel subfamily H member 1, Ether-a-go-go potassium channel 1, EAG channel 1, bEAG, Voltage-gated potassium channel subunit Kv10.1.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv10.1/KCNH1 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Nucleus inner membrane; Multi-pass membrane protein. Cell projection, dendrite. Cell projection, axon. Presynaptic cell membrane. Perikaryon. Postsynaptic density membrane. Early endosome membrane. Note=Perinuclear KCNH1 is located to NPC-free islands.
Protein: CTL2A_XENLA
Sequence: MRLRMRKGSPRSSHVAAVRTARCKRKHSEEDEEEESPLIEEDKLPKQETGLLSTIKNFIKGSTNKEDRENPAKRSKVERDLDNNLITSTPRTGDKPSKPIARVRRKSQVNGEATAYEVSQHMKQNGKLEDLPCTTSPPRTTLLGTIFSPVFNFFSPANKNGTSGSDSPGQAVEAEEIVKQLDMEKVDEFSTSTATNGASYPSLGAPVRSTAGSWLEGTEDTPERDIPPLTAPVSPESGYSSAHAEAAYEEDWEVFDPYFFIKHVPPLTEEQLNRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQIYEIILFTASKKVYADKLLNILDPKKRLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDKNDKELLKLVPFLENLVELNEDVRPHVRDRFRLHDCLPPD
What is the function of this protein?
Probable phosphatase.
What are the official names of this protein?
CTD small phosphatase-like protein 2-A, CTDSP-like 2-A.
What is the protein family that this protein belongs to?
Belongs to the CTDSPL2 family.
Protein: CMR1_ASPCL
Sequence: MGTDSTELSEFEKQRLANIAERDALLKKLTLDAQSSGIFPPKLARSSPVSQTKPKKKPAPKKIKKEGEAPVARRMSSRLRGIAAESEVAKRKAEEHYEAVQQAERAKRVRKSDAFSFSEMLVSGQKLSADGLIGVDVVTKGVAMPYQRTFGDEDIEKTADKELKRLREEVSGLQLWEAWEPNRIKVTPERIYTMTFHPSEAKPLIFAGDKMGNLGVLDASQERPVSSIKHEDGDEEEQEDDDDPDPVLTTLKPHTRTISSMHIHPSKPTHLYTASYDSSIRELDLEKTTSVETYAPDSPSDDVPISGIDMAADDPNTLYWTTLDGAFGRYDTRASRRTAVATWQLSEKKIGGFSLYPTHPHFFATASLDRTMRLWDLRKLSHDDPLPVGEHLSRLSVSHAAFNSAGQVATSSYDDSLKIYDFGAKGIASWEQGHTLSDAEMKPDTVVRHNCQTGRWVTILRPQWQANPQSHIQRFCIGNMNRFVDVYSSSGDQLAQLGGDGITAVPAVAVFHRSKNWIAGGTASGKICLWM
What is the function of this protein?
DNA-binding protein that binds to both single- and double-stranded DNA.  Binds preferentially to UV-damaged DNA.  May be involved in DNA-metabolic processes.
What are the official names of this protein?
DNA damage-binding protein cmr1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat DDB2/WDR76 family.
Protein: RL31_SPOFR
Sequence: MAKPKGERKGKSAINEVVTREYTVNLHKRLHGVGFKKRAPRAIKEIRKFAEKQMGTPDVRVDTRLNKFLWSKGVRNVPFRVRVRLSRRRNDDEDSAHKLFTLVTYVPVASIKGLQTENVDASQE
What are the official names of this protein?
60S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL31 family.
Protein: HOA2_NOVAD
Sequence: MTFDPTSDRLYIQDVTLRDGMHAILHMYGTDSVRTIAKALDEAGVDAIEVSHGDGLNGSTFNYGFGAHTDWDWIEAAADVIKNAVLTTLLVPGIGTAEELKRAYSMGVRSVRVATHCTEADVGKQHIGIARDLGMDVSGFLMMSHMIEPEALAQQALLMESYGAHCVYVTDSGGALDMDGVIARLQAYDRVLKPETQRGIHAHHNLSLGVANSIVAAQAGAVRIDASLAGMGAGAGNAPLEVFIAAANRKGWKHGCDVMALMDAADDIIRPLQDRPVRVDRETLSLGYAGVYSSFLRHAEKAAEQYGIDTREILVELGNRRMVGGQEDMIIDVALDLIKAKAN
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase 2, HOA 2, 4-hydroxy-2-keto-pentanoic acid aldolase 2, 4-hydroxy-2-oxopentanoate aldolase 2.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: FLAB2_NATMM
Sequence: MFTNDTDDGRGQVGIGTLIVFIAMVLVAAIAAGVLINTAGMLQSQAEATGEESTDLVSERIDTTSAVGTVSTHVADGEDGADRGDLAEISIGVTGAPGADDIDLNETIIQVVGPEGQENLVMADGSNDMSEAGWDETSTTDIGSTESTDQGDTDDDVNASNIESGYFAVENEDGYFVEGSDAVLDDNNGELTIVFNPKVAPFGEADDVSGITPGDLHEDDVFGAGDEASVDIVSPSGATTSVELNSPDLFSEPGEAVRL
What is the function of this protein?
Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.
What are the official names of this protein?
Flagellin B2.
What is the protein family that this protein belongs to?
Belongs to the archaeal flagellin family.
What are the subcellular locations of this protein?
Archaeal flagellum.
Protein: RSMH_METRJ
Sequence: MSRRRPAPESSPRHDGADAPPEPHVPVLLAEVVEALGTEGGTAVDGTFGAGGYTRALLAADPALQVVAIDRDPTAIAGGQALVAESGGRLRLLPGRFGDLDGLLAEAGIAQVDRVVLDIGVSSMQLDAPERGFSFRSDGPLDMRMACDGPSAADLVNEADETVLADIIYHFGEERRSRAVARTILEARRRGRIETTAQLAELVAGVVRTEPGSHIHPATRTFQGLRIAVNDELGELVRALHAAERVLRPGGRLAVVTFHSLEDRIVKQFFAARSGRSAQGSRHLPGGPVETVRSFRPVTKGPVLPGEAETARNPRARSAKLRAAERTESDVPEPLAALTALASLPDAARGHRR
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 5EAS3_NICAT
Sequence: MASAAVGNYEEEIVRPVADFSPSLWGDQFLSFSIENQVAEKYAQEIEALKEQTRSMLLENGRKLADTLYLIDIIERLGISYHFEKEIDDILDQIYNQNSNCNDLCTSALQFRLLRQHGFNISPEIFSKFQDENGKFKESLASDFLGLLNLYEASHVRTHADDILEEALAFSTIHLESAAPHLKSPLREQVTHALEQCLHKGVPRVETRFFISSIYEKEQSKNDVLLRFAKLDFNLLQILHKQELAEVSRWWKDLDFVTTLPYARDRVVECYFWALGVYFEPQYSQARVILVKTISMISIVDDTFDAYGTIKELETYTDAIQRWDINEIDRLPDYMKISYKAILDLYKDYEKELSSAGRSHIVCHAIERMKEVVKNYNVESTWFIEGYMPPVSEYLSNALATTTYYYLATTSYLGMKSATEQDFEWLSKNPKILEASVIICRVIDDTATYEVEKSRGQIATGIECCMRDYGVSTKEAMAKFQGMAEAAWKDLNEGFLRPTPVSTEILFRILNLARIVEVTYIHNLDGYTHPEKVLKPHINALLVDSIEI
What is the function of this protein?
Catalyzes the cyclization of trans,trans-farnesyl diphosphate (FPP) to the bicyclic intermediate 5-epi-aristolochene, initial step in the conversion of FPP to the sesquiterpenoid antifungal phytoalexin capsidiol.  Produces germacrene A as an enzyme-bound intermediate that is not released by the enzyme, but is further cyclized to produce the bicyclic 5-epi-aristolochene.
What are the official names of this protein?
5-epi-aristolochene synthase 3, NaEAS12.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCSA_LEMMI
Sequence: MIFVTLEHILTHISFSIISVVIIIQLMTFFVHEIPALSDSLEKGMIATFLSITGLLIIRWIYSGHFPLSNLYESLMFLSWSFAIIHMIPKIWNHKNKNYLSAITIPSAIFTQAFATSGLSTEMHESGILVPALRSHWLMMHVSMMLLSYAALLVGSLFSIALLVITFRKNGKLVVENQNLLIGSSFFDQMDYLNFNENINVLENPSFSSSFKNYYKYQLVERLDYWSSRVISIGFSFLTIGILSGAVWANEAWGSYWNWDPKETWAFITWTIYAIYSHTRTTKNGQGANSAIVASIGFFIIWICYFGVNLLGIGLHSYGSFILS
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: NRDR_GLAP5
Sequence: MRCPFCATDDTKVVDSRLTADGYQIRRRRECPVCKERFTTFESAELLIPHIVKNNGSREPFDERKLRTSLSRALEKRPVSTDDVEQAIHRIVLQLQATGEREVASKFVGDLVLGELKSLDKVAYIRFASVYLSFDDVEEFSKEIERLRN
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: GPMA_ALKEH
Sequence: MKKLVLLRHGQSIWNQENRFTGWHDVDLTEKGREEAQAAGQLMKRHGLRFDYAYTSVLKRAIRTLWIGLDELDQMWIPVTKAWQLNERHYGALTGLNKAETAEEYGAEQVHIWRRSYDTPPPPLDETSPYHPRHDPRYASLKPEQLPATESLALTLERVLPYWNERIVPTLRDCDNVLIAAHGNSIRALIKHLDGLDDEAIMKVEIATGDPLVYELDDALAVVDKHYLRERD
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: MYOA_PLAF7
Sequence: MAVTNEEIKTASKIVRRVSNVEAFDKSGSVFKGYQIWTDISPTIENDPNIMFVKCVVQQGSKKEKLTVVQIDPPGTGTPYDIDPTHAWNCNSQVDPMSFGDIGLLNHTNIPCVLDFLKHRYLKNQIYTTAVPLIVAINPYKDLGNTTNEWIRRYRDTADHTKLPPHVFTCAREALSNLHGVNKSQTIIVSGESGAGKTEATKQIMRYFASSKSGNMDLRIQTAIMAANPVLEAFGNAKTIRNNNSSRFGRFMQLVISHEGGIRYGSVVAFLLEKSRIITQDDNERSYHIFYQFLKGANSTMKSKFGLKGVTEYKLLNPNSTEVSGVDDVKDFEEVIESLKNMELSESDIEVIFSIVAGILTLGNVRLIEKQEAGLSDAAAIMDEDMGVFNKACELMYLDPELIKREILIKVTVAGGTKIEGRWNKNDAEVLKSSLCKAMYEKLFLWIIRHLNSRIEPEGGFKTFMGMLDIFGFEVFKNNSLEQLFINITNEMLQKNFVDIVFERESKLYKDEGISTAELKYTSNKEVINVLCEKGKSVLSYLEDQCLAPGGTDEKFVSSCATNLKENNKFTPAKVASNKNFIIQHTIGPIQYCAESFLLKNKDVLRGDLVEVIKDSPNPIVQQLFEGQVIEKGKIAKGSLIGSQFLNQLTSLMNLINSTEPHFIRCIKPNENKKPLEWCEPKILIQLHALSILEALVLRQLGYSYRRTFEEFLYQYKFVDIAAAEDSSVENQNKCVNILKLSGLSESMYKIGKSMVFLKQEGAKILTKIQREKLVEWENCVSVIEAAILKHKYKQKVNKNIPSLLRVQAHIRKKMVAQ
What is the function of this protein?
Myosins are actin-based motor molecules with ATPase activity.  Unconventional myosins serve in intracellular movements.  Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity).
What are the official names of this protein?
Myosin-A, PfMyoA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Tightly associated with the plasma membrane.
Protein: ILVC_METKA
Sequence: MAKIYGDEDASLEPLEDKTVAVIGYGSQGEAQAKNLRDSGIDVIIGVREGGPSWERAKKDGFEVLPIPEAAEAGDVVHILIPDEVQPQVYREHIHDNLEKGNALGFSHAYNIHYGLIEPPEYVDVILVAPKGPGHMVRKLYTEGFGTPALVAVHQDYTGEAMDLALAMAKAMGFTRAGVIKTTFREEVETDLFGEQVDLVGGVLYMILYAFETLVEAGYQPEVAYFETLHELKLIVDLIYEKGLSGMLDNVSNTAEYGGLTRGKRIINKEEMRKVLEEIRSGEFAREWTLENESGRIVMKRLREEIENHEIEKVGERLRKMMGFED
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: PCTM_RHIS2
Sequence: MSANHTRMIDLSKFAEAKNAALLTFCSVWMGAIITLLRSPDELPLGFDYAFKASLTVLFIAAIISLKSLMPKFLNQVHKREDEYKNLLYFGDIDQIGTGAYPGMAADLYTPTEGASATPTYLHDLAVQTAIHAKIAHRKFRLFNWAGSLVLFAFGIMMVPPILFCIRWAVNRLHC
What is the function of this protein?
The effector gene of a two-gene Pycsar system.  Expression of this and uridylate cyclase RsPycC (AC A0A4R2TZQ0) probably confers resistance to bacteriophage.  The genes are probably only expressed in response to bacteriophage infection.  Probably only responds to cUMP (produced by its cognate NTP cyclase), acts by impairing membrane integrity.
What are the official names of this protein?
Pycsar effector protein RsPycTM, RsPycTM.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HBB1_SPHPU
Sequence: VHWTAEEKHLLGSLWAKVDVADIGGEALGRLLVVYPWTQRFFADFGNLSSATAICGNPRVKAHGKKVFTMFGEALKHLDNLKETFASLSELHCDKLHVDTENFKLLGNLVIVVLAARLHDSFTPAAQAAFHKLAYSVAHALARRYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta-1, Beta-1-globin, Hemoglobin beta-1 chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: NNJA2_WHEAT
Sequence: MASRDFLGRFGGEKGSSSDKAGGGAGEPDEVVELSLGLSLGGCFGANSGRDAKKPRLVRSSSLAAMYSLPGTSDDLAAATPPPAPLMRTSSLPTETEEERWRRREMQSLKRLQAKRKRLERRTSMNSGKSGGSSSRDDAQEPLYPSAFQLRRSVVDQGNTSSSMPEQGSADGAEAKSTSSMEISSDNNNNNNASNQNKSLPPPAPSPAGKLPNGIVKEQPPLRTLRSLTMRTTSTGDLRKSMMEDMPMVSSKVDGPNGKKIDGFLYKYRKGEEVRIVCVCHGNFLTPAEFVKHAGGGDVTNPLRHIVVNPAPSVFL
What are the official names of this protein?
Ninja-family protein 2, ABI five-binding protein B1, ABI5-binding protein B1, TaAFP-B1.
What is the protein family that this protein belongs to?
Belongs to the Ninja family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL4_HAEI8
Sequence: MELQVVGANALTVSETTFGREFNEALIHQVVVAYAAGARQGTRAQKTRAEVSGSGKKPWRQKGTGRARAGDIKSPIWRSGGTTFAAKPQDHSQKVNKKMYRGAIKSILSELVRQDRLVVVEKFELDAPKTKVLVQKLKDLAVEDALIITASLDENLFLAARNLYKVDVRDVQGIDPVSLIAFDKVIVTVDAVKQIEEILA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: METAA_SUCHY
Sequence: MPINIPNGLPAASVLAGEQIFVMTEERATHQDIRPLTLLFLNLMPKKIATEIQYMRKLSNTPLQVNIDLLRVDKHISKNTPQPHLDTFYKDFEEIEGRNYDGMIITGAPLDQIDFSDVTYWDKLEKIITWSKEHVTSTLFSCWGVAAGLKIFYDLPLINRKEKLSGVFLHHTAQSLNPLIRGFDDTFLAPHSRFIDFPSDVIRKHTDLEILADSEITGMFLAATPDRRQVFVTGHPEYDATTLSDEYRRDLAAGKDPKLPENYFPHDDPTQIPSCVWRSHASLLFGNWLNYYVYQITPYKW
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAZ_TROW8
Sequence: MFLGTHPVRLDDKNRFVLPAKFRGMLDSVVLTRGQERCLYLFDRSEFERISDGIRNTALSQKKVRDYLRIFLSGAAAQLPDRQHRIVIANHLRAYADLKKEVTVIGAGKHIEIWDSEAWSSYLEEQEAAFSEIAEEVIPGLI
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: PBPA_RICTY
Sequence: MYKSLFFFLKIFAILILLGCSVTAYIIYHYSHDLPDYSQLVRYYPPSVTRIYSRDGKLMEEYAFERRVFVPINNVPSSLIESFIAAEDKNFYNHPGIDLLGIVRAAFLNISNYLHNRRMEGASTITQQVVKNFLLTNEVSLERKIKEVIISYMISRVFTKHQILELYLNQTFFGRGAYGVAAAAQNYFNKSIEELTIAESAFIAALPKAPSELNPDKNYSRVKARRDYVIERMFEDGYITRDTMKEAIGSPIVLRKRAKEETVTADYYAAQVREEVIKMLNSKEEFYRGGLTIITSLDAQMQKLAENALRKGLREFDRRHGFRKPIANIPLDHWQEALKNIPTPSSLLEYKLAVVLDVSDNHAKIGLIDGSKARIPIIEMQWARSNLKSVKTLLKKGDVIVVEPIKDCYALRQIPEINGAIMVMNPHTGQVLASVGGYDFSTSKFDRVTQALRQPGSLTKTFVYLAALENGVKPNQIFNDGPIEIMQGPGMPSWRPKNYEGQFLGEMTMRTGFEKSRNLITVRVATAVGLTKIVDIIKRFGINNEPKKVYSMVLGSIETTLSRITNAYAIIANGGKKVEPHFIELIKDRNGKIIYRRDNRECFSCNILDSDLDTAILEIPKEDIYRVTDEASDYQITSFLTGAIDSGTGYAARKLGKIIAGKTGTSNDSKDTWFIGFTPKIVVGSYVGYDTPKELGKKATGSNVVLPIFIDFMNHAYKDEPSLPFKVPDSIKLIAVDRITGKMIPDGTVIEAFKVNNIQMLENDYMIDNHDIFIPGISDQSQEIY
What is the function of this protein?
Cell wall formation.  Synthesis of cross-linked peptidoglycan from the lipid intermediates.  The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
What are the official names of this protein?
Penicillin-binding protein 1A, PBP-1a, PBP1a.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transpeptidase family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.