PharMolix/UniProtQA huggingface dataset:
Protein: CTNB_URECA
Sequence: METYQQMNSGSGPRSVGTPQGQYMDVGEMPPMDAKQQTMLWQQNQYMGDSGIQSGATTQAPPSVSSKHGLDDMDTGEGMDTSRMMFDFDQGFSTQAFTQEQVDEMNQQLNQTRSQRVRAAMFPETLEEGVQIPSTQLDPGQPTAVQRLSEPSQMLKHAVVNLINYQDDADLATRAIPELTKLLNDEDQVVVSQAAMMVHQLSKKEASRHAIMNSPQMVAALVRAMTNTNDLETTRCAAGTLHNLSHHRQGLLTIFKSGGIPALVKLLSSPVESVLFYAITTLHNLLLHQEGSKMAVRLAGGLQKMVLLLQRNNLKFLAITTDCLQILAYGNQESKLIILASGGPGELVRIMRSYTYEKLLWTTSRVLKVLSVCASNKPAIVEAGSAGPSMHLGHQSQRLVQNCLWTLRNLSDAATKSSDIEGLLQMLVQLLASNDINIVTCAAGILSNLTCNNQRNKVTVCQVGGIEALVRTILQAGDREDITEPAVCALRHLTSRHGEAEMAQNAVRLHYGLPVLVKLLHPPSRWPLIKAVVGLIRNLALCPANHAPLREHGAIPRIVQLLIRAHQDTQRRATAGSGNTSAYVDGVRMEEIVEGTVGALHIMAREAHNRAVIRGLNCISLFAQLLYSPIDNIQRVAAGVLCELAADKEGAEMIEQEGTTAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRGEQVPWGEPPGLDDMDSSQLLPEEQGFRGYQGSGPGSVPSGPPHDMNRQDSMQGLELGSQQGTAYGSHMPDLGPNTDLHFDPMDGGGSSMGGPHTPTDPQNQMAAWFDTDL
What is the function of this protein?
Binds to the cytoplasmic domain of the cell-cell adhesion molecule E-cadherin, and perhaps to other (membrane) proteins.  The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties.
What are the official names of this protein?
Catenin beta, Beta-catenin.
What is the protein family that this protein belongs to?
Belongs to the beta-catenin family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton.
Protein: TRMFO_STAA8
Sequence: MTQTVNVIGAGLAGSEAAYQLAERGIKVNLIEMRPVKQTPAHHTDKFAELVCSNSLRGNALTNGVGVLKEEMRRLNSIIIEAADKARVPAGGALAVDRHDFSGYITETLKNHENITVINEEINAIPDGYTIIATGPLTTETLAQEIVDITGKDQLYFYDAAAPIIEKESIDMDKVYLKSRYDKGEAAYLNCPMTEDEFNRFYDAVLEAEVAPVNSFEKEKYFEGCMPFEVMAERGRKTLLFGPMKPVGLEDPKTGKRPYAVVQLRQDDAAGTLYNIVGFQTHLKWGAQKEVIKLIPGLENVDIVRYGVMHRNTFINSPDVLNEKYELISQPNIQFAGQMTGVEGYVESAASGLVAGINLAHKILGKGEVVFPRETMIGSMAYYISHAKNNKNFQPMNANFGLLPSLETRIKDKKERYEAQANRALDYLENFKKTL
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRTN_STAA8
Sequence: MKIAVIGAGVTGLAAAARIASQGHEVTIFEKNNNVGGRMNQLKKDGFTFDMGPTIVMMPDVYKDVFTACGKNYEDYIELRQLRYIYDVYFDHDDRITVPTDLAELQQMLESIEPGSTHGFMSFLTDVYKKYEIARRYFLERTYRKPSDFYNMTSLVQGAKLKTLNHADQLIEHYIDNEKIQKLLAFQTLYIGIDPKRGPSLYSIIPMIEMMFGVHFIKGGMYGMAQGLAQLNKDLGVNIELNAEIEQIIIDPKFKRADAIKVNGDIRKFDKILCTADFPSVAESLMPDFAPIKKYPPHKIADLDYSCSAFLMYIGIDIDVTDQVRLHNVIFSDDFRGNIEEIFEGRLSYDPSIYVYVPAVADKSLAPEGKTGIYVLMPTPELKTGSGIDWSDEALTQQIKEIIYRKLATIEVFEDIKSHIVSETIFTPNDFEQTYHAKFGSAFGLMPTLAQSNYYRPQNVSRDYKDLYFAGASTHPGAGVPIVLTSAKITVDEMIKDIERGV
What is the function of this protein?
Involved in the biosynthesis of the yellow-orange carotenoid staphyloxanthin, which plays a role in the virulence via its protective function against oxidative stress.  Catalyzes three successive dehydrogenation reactions that lead to the introduction of three double bonds into 4,4'-diapophytoene (dehydrosqualene), with 4,4'-diapophytofluene and 4,4'-diapo-zeta-carotene as intermediates, and 4,4'-diaponeurosporene (the major deep-yellow pigment in staphylococci strains) as the end product.
What are the official names of this protein?
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming), Dehydrosqualene desaturase.
What is the protein family that this protein belongs to?
Belongs to the carotenoid/retinoid oxidoreductase family. CrtN subfamily.
Protein: SYGB_PERMH
Sequence: MKKYLLEIGCEELPPKAVDTAISYFKERLEGLFENFFEYRTEENISVFGTPRRIGFILSNLREKEPSEEKTILGPPAKVGIDEKGNFTKAALAFASKNNIPVEQLKIIENEKGRYIGATLIKEGKDIRTFIQEVIPDLITKIPFPKLMRWNETGFRFSRPVRWIVSLLDNEVVSFSIAGIDADRYTHLHRFMTTPTGRGERKKIPDVDSYFQIMKLGFIIPKYEERKEAVKTQLTGFANSINAEPVIDEDLLDEVTNLTEFPVGILGDFSPEYLILPKEVIITVCKVHQRYFNFEKDGKLIPKFLAFSNTAVKDREKVKSGYEKVLKARLEDALFFYEEDLKHNLEDFYPQLEGIQFHHKLGSMLDKVKRNGEIAVLLSRELNFENLKDLLRANKLSKCDLLTEMVKEFDELQGIMGMHYALKQGEKEEVAKAIYEHYLPKTSDDQLPETDIGTLLSLSDKLDTVISFISIGEKPKATADPFGIRRNSIGIVRILVEKGIDLDLKKLLQDISREARKVKILRLADIEKEWEIIFDERTIPEILDFIEGRFIAYMKDKGFDTDIINSVVSVDSYNLYRNYLKIKSIQELKKNPEFTDIMTVFKRVGRIIPEEFEEHFNPDTLVQDEEKELYRKYTEVNKIFSKDVEDRRYTEALNELLKMKPFIDKFFDNVMVMTEDKKLRENRLSLMKLINNMFRKIADFTKITT
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_DUGDU
Sequence: MTNIRKSHPLIKILNNSFIDLPTPVNISSWWNFGSLLGACLIIQILTGLFLAMHYTSDTLTAFSSVTHICRDVNYGWIIRYLHANGASMFFLCLYAHIGRGIYYGSYLYPETWNIGIVLLLTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWVWGGFSVDKATLTRFFALHFILPFIVTALVMVHLLFLHETGSNNPTGLISDSDKIPFHPYYSVKDLLGLFLLILVLLLLTLFSPDMLGDPDNYTPANPLNTPPHIKPEWYFLFRYAILRSIPNKLGGVLALVLSILILALLPLLHTSKQRSLSFRPLSQCLFWILVADLITLTWIGGQPVEHPYIIIGQLASILYFSIILIFMPIAGLIENHLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: YIP4B_ARATH
Sequence: MSHNDTIPLYQSSQSDIDEIENMMNDSFQSGPGTVLPARPPSPIRPSIPVSSSPFVQSNLPPLPPSSSSSTQKVMPVPAPPPLPSAGNEGNKSIGGSGFGSPPNTLTEPVWDTVKRDLSRIVSNLKLVVFPNPYREDPGKALRDWDLWGPFFFIVFLGLTLSWSASVKKSEVFAVAFALLAAGAVILTLNVLLLGGHIIFFQSLSLLGYCLFPLDVGAVICMLKDNVILKMVVVSVTLAWSSWAAYPFMSAAVNPRRKALALYPVFLMYVSVGFLIIAIN
What is the function of this protein?
Together with YIP4A, involved in the regulation of cell elongation during root and hypocotyl growth (PubMed:23832588).  YIP4A and YIP4B are central trafficking components in Rho-of-plant (ROPs, e. g.  ARAC4/ROP2, ARAC5/ROP4 and ARAC3/ROP6) small GTPases-dependent root hair formation, thus contributing to activation and plasma membrane accumulation of ROPs during hair initiation (PubMed:30770391).  The ECH/YIP4 complex is involved in the modulation of the trans-Golgi network (TGN)-mediated trafficking of some proteins and cell wall components (e. g.  pectin and hemicellulose) to the cell wall in dark-grown hypocotyls and in secretory cells of the seed coat (PubMed:23832588).
What are the official names of this protein?
Protein YIP4b, YPT/RAB GTPase-interacting protein 4b, YIP4b.
What is the protein family that this protein belongs to?
Belongs to the YIP1 family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein.
Protein: CLPP1_TROW8
Sequence: MSETKQTVFDRLLQERIVWLGEAIDDKLANEICAKILLLNADDPKEDIFLYINSPGGSITAGMAIYDTMQFVSNDIVTVGIGMAASMGQVLLTSGTQNKRYIMPNARVLLHQPLAGFGGTASDIQTQAKLILDMKYRLSQITASRTGKTVEQIMEDGDRDHWFTAEEALEYGFVDHIRTE
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 1, Endopeptidase Clp 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR2_TOXGO
Sequence: MILLKLNSLINIPIYIGSATSYRQKKFINYIYKKYNNKHFFNIFIILKYLSKAYLYLYILSKYNRSLLFLNSSIKNFNLIKSLANLTNNFYINFFYKIDFLFNWIMFKNKLILLKWLKQLYTFYLKYLFNYLPYNLLIKLYYIYINILKKFGGLEYMQKLPKNIFICNSYSNYLYKNLNLKNFLIISIVDINNENTLKNISVRIIGNNKSYLAIKFIFNILLTALLHGSLFNK
What are the official names of this protein?
30S ribosomal protein S2, apicoplast.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Plastid, apicoplast.
Protein: RF2_LEUMM
Sequence: MEIIDAKHAVSDMQENIERFRGTLDMEALTEEIADYENRMTEPDFWNDNEKAQKVIEENNVLKNRRDSFLNLTNQVEELELLIEMAVEDPEDEDTLGELEAGVAKAQKDIDAYNLEQLLTEPYDANNAILEIHPGSGGTESTDWGANLYRMYTRWAQQHDFQVETLDYHAGDEAGIDSATIKVTGHNAYGFLRSEKGVHRFVRISPFDSAGRRHTSFVSVDVMPELDDSIEVEVRDDDVKMDVFRSGGAGGQNVNKVSTGVRLTHEPTGIVVSSTVERTQYGNRDYAMRLLKSKLYQLELEKKEAERAALTGEKMENGWGSQIRSYVLHPYQMVKDHRTNYETNQPQAVLDGDLDPFINAYLQWQLSLKNPN
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y567_BACAC
Sequence: MGFPKVERLLINYKTLDEFKKFKGCGAQELSMLEELQANIIENDSESPFYGIYYGGSLIARMSLYMKRNGGEPFEITGTYLELYKLEVLPNFQKQGFGEMLVNYAKGLQFPIKTIARIHSAGFWDKLNFQPVSVPDGDFYVWHPETNLNAVTNEESA
What are the official names of this protein?
Uncharacterized N-acetyltransferase BAMEG_0567.
Protein: MAMY_MAGSA
Sequence: MAIAAIMGDVLMLMGFNKAAFGKLNSASRAALIGAVIWAVLSIVYLTIFNGWKNLFTMLPHEFFIVLLSIALPIGLTVLILMLSRIVKSVDTLKSEVTTLSRNDVSSEGSVAMLADLFREHRAAIAAQVEAQVEATTQLIRLNQEGRALAAPAQASGTDEAMTLLAQLFREHREAVAAQLEAQASATAQLVQVTRDSRDGIVDELRSQRVLSQEITQELSQITQSRTVAPAPPGLDPSQRIDRMRALAEVLGLALNDLSMTATQVLTEHLNAAHGDRDGTRKFISTLTTAYFAGDKNVFFRSLVQEAVNRSEQLRRCAEDTESVRQQISKILREAREIRSLVAACDPNDLVRIVFEDGELWALEKALAEHFLIDGSPVWTETAPDSGMD
What is the function of this protein?
Causes tubulation when added to magnetosome-derived liposomes, binds liposomes; may be involved in constriction of the cell inner membrane to form mature magnetosomes (PubMed:20345667).  Binds preferentially to cardiolipin, a component of bacterial membranes, with very poor to no binding of other tested (phospho)lipids.  Addition of cardiolipin to magnetosome-derived lipids increases tubulation (PubMed:30039923).  May function with MamX, MamZ amd Mms6 (By similarity).
What are the official names of this protein?
Liposome tubulation protein MamY.
What is the protein family that this protein belongs to?
Belongs to the magnetosome MamY family.
What are the subcellular locations of this protein?
Magnetosome membrane; Multi-pass membrane protein. Note=Primarily associated with immature magnetosomes with small magnetite crystals, but longer than the usual magnetosome chain.
Protein: ASTN2_HUMAN
Sequence: MAAAGARLSPGPGSGLRGRPRLCFHPGPPPLLPLLLLFLLLLPPPPLLAGATAAASREPDSPCRLKTVTVSTLPALRESDIGWSGARAGAGAGTGAGAAAAAASPGSPGSAGTAAESRLLLFVRNELPGRIAVQDDLDNTELPFFTLEMSGTAADISLVHWRQQWLENGTLYFHVSMSSSGQLAQATAPTLQEPSEIVEEQMHILHISVMGGLIALLLLLLVFTVALYAQRRWQKRRRIPQKSASTEATHEIHYIPSVLLGPQARESFRSSRLQTHNSVIGVPIRETPILDDYDCEEDEEPPRRANHVSREDEFGSQVTHTLDSLGHPGEEKVDFEKKAAAEATQETVESLMQKFKESFRANTPIEIGQLQPPLRSTSAGKRKRRSKSRGGISFGRAKGTSGSEADDETQLTFYTEQYRSRRRSKGLLKSPVNKTALTLIAVSSCILAMVCGSQMSCPLTVKVTLHVPEHFIADGSSFVVSEGSYLDISDWLNPAKLSLYYQINATSPWVRDLCGQRTTDACEQLCDPETGECSCHEGYAPDPVHRHLCVRSDWGQSEGPWPYTTLERGYDLVTGEQAPEKILRSTFSLGQGLWLPVSKSFVVPPVELSINPLASCKTDVLVTEDPADVREEAMLSTYFETINDLLSSFGPVRDCSRNNGGCTRNFKCVSDRQVDSSGCVCPEELKPMKDGSGCYDHSKGIDCSDGFNGGCEQLCLQQTLPLPYDATSSTIFMFCGCVEEYKLAPDGKSCLMLSDVCEGPKCLKPDSKFNDTLFGEMLHGYNNRTQHVNQGQVFQMTFRENNFIKDFPQLADGLLVIPLPVEEQCRGVLSEPLPDLQLLTGDIRYDEAMGYPMVQQWRVRSNLYRVKLSTITLAAGFTNVLKILTKESSREELLSFIQHYGSHYIAEALYGSELTCIIHFPSKKVQQQLWLQYQKETTELGSKKELKSMPFITYLSGLLTAQMLSDDQLISGVEIRCEEKGRCPSTCHLCRRPGKEQLSPTPVLLEINRVVPLYTLIQDNGTKEAFKSALMSSYWCSGKGDVIDDWCRCDLSAFDANGLPNCSPLLQPVLRLSPTVEPSSTVVSLEWVDVQPAIGTKVSDYILQHKKVDEYTDTDLYTGEFLSFADDLLSGLGTSCVAAGRSHGEVPEVSIYSVIFKCLEPDGLYKFTLYAVDTRGRHSELSTVTLRTACPLVDDNKAEEIADKIYNLYNGYTSGKEQQMAYNTLMEVSASMLFRVQHHYNSHYEKFGDFVWRSEDELGPRKAHLILRRLERVSSHCSSLLRSAYIQSRVETVPYLFCRSEEVRPAGMVWYSILKDTKITCEEKMVSMARNTYGESKGR
What is the function of this protein?
Mediates recycling of the neuronal cell adhesion molecule ASTN1 to the anterior pole of the cell membrane in migrating neurons.  Promotes ASTN1 internalization and intracellular transport of endocytosed ASTN1 (By similarity).  Selectively binds inositol-4,5-bisphosphate, inositol-3,4,5-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, suggesting it is recruited to membranes that contain lipids with a phosphoinositide headgroup (Ref. 6).
What are the official names of this protein?
Astrotactin-2.
What is the protein family that this protein belongs to?
Belongs to the astrotactin family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Perikaryon. Cytoplasm, cell cortex. Early endosome. Late endosome. Cytoplasmic vesicle, clathrin-coated vesicle. Cytoplasmic vesicle. Note=Integral membrane protein not detected at the cell membrane. Detected in cytoplasmic vesicles in the cell cortex, close to the anterior pole of migrating neurons. Detected at the base of the leading process in migrating neurons.
Protein: HFLD_BUCAT
Sequence: MKKIHLITLSLAGICQSAHLVQQLAYSGKCDSNAFSICLKSILEINPTSFIAIYGNHEKNLIIGLEILLSTLTFSSFSYSYIELIKYISNMMIIEKKLKKSRTAIYSLKNKISVISSEYYLNYNIKNLTRKLGELYLEIISSLGSRIVIKGIKDFLQDHQIQEKIRCLLFSGIRAIVLWKQYGGNQLQLIYFRYFIIKKAKKILYHLKDAT
What are the official names of this protein?
High frequency lysogenization protein HflD homolog.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ISPH_HELPJ
Sequence: MEIKMAKDYGFCFGVKRAIQIAEKNQNSLIFGSLIHNAKEINRLEKNFNVKIEEDPKKIPKNKSVIIRTHGIPKQDLEYLKNKGVKITDATCPYVIKPQQIVESMSKEGYQIVLFGDINHPEVKGVISYATNQALVVNSLEELQEKKLQRKVALVSQTTKQTPKLLQIASYLVERCTEVRIFNTICNATSYNQKAALDLSKEVDIMIVVGGKTSSNTKQLLSIAKQHCKDSYLVEDENELELAWFKDKKLCGITAGASTPDWIIENVKQKISTI
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: CCME_SERP5
Sequence: MNPRRKSRLYLAIVVLIGVALTATLMLYALRSNIDLFYTPSEILQGKGENHEKPEVGQRLRIGGMVMPGSVKRDQKTLQVSFKVYDARGAIDVTYTGILPDLFREGQGVVAQGVLGEGNVVNAREVLAKHDEKYTPPEVADAMKENHKGPASAYATPQNEGAKS
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: DXS_THIDA
Sequence: MPASLLDTIESPADLRALPAAELPGLAAEVRAFLIDSVAGTGGHLASNLGAVELTLALHYVFDTPRDRIVWDVGHQSYTHKILTGRRDAMQGLRQRGGIAGFPRRAESEFDAFGTGHSSTSISAALGMAEAFHQLGSDQRAVAVIGDGAMTAGMAFEALNNAGATELPLLVVLNDNDMSISPNVGALNNYLARLMSGRFYAAARRAGDKVLSVAPPIRELAKRAEEHMKGMVTPGTLFEEFGFNYIGPIDGHDLDVLVNTLRNIRHLRGPQFLHVVTRKGKGYTPAETNPCLYHGVARFDPAAGVAEKRAGKPSYTEVFGDWLCDMAASDPRLVGITPAMREGSGLVRFSQEFPERYFDVGIAEQHALTFAAGLACEGVKPVVAIYSTFLQRAYDQLIHDIALQNLPVTLAIDRAGLVGADGPTHAGSFDLSFLRCVPDLVIAAPSDENECRRLLSTAFLHDGPAAVRYPRGCGTGAAIEPGLEPVEIGKGVCRRRGRDVALLAFGSLVAPALTAAERLDATVADMRFVKPLDVDLVGELAAGHRLLVTLEENAVAGGAGAAVAELLAQLGIVVPVLQLGLSDVFIEHGDAAAMLAACGLDAPGIERAVSERLAALPE
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: TRXR2_HUMAN
Sequence: MAAMAVALRGLGGRFRWRTQAVAGGVRGAARGAAAGQRDYDLLVVGGGSGGLACAKEAAQLGRKVAVVDYVEPSPQGTRWGLGGTCVNVGCIPKKLMHQAALLGGLIQDAPNYGWEVAQPVPHDWRKMAEAVQNHVKSLNWGHRVQLQDRKVKYFNIKASFVDEHTVCGVAKGGKEILLSADHIIIATGGRPRYPTHIEGALEYGITSDDIFWLKESPGKTLVVGASYVALECAGFLTGIGLDTTIMMRSIPLRGFDQQMSSMVIEHMASHGTRFLRGCAPSRVRRLPDGQLQVTWEDSTTGKEDTGTFDTVLWAIGRVPDTRSLNLEKAGVDTSPDTQKILVDSREATSVPHIYAIGDVVEGRPELTPIAIMAGRLLVQRLFGGSSDLMDYDNVPTTVFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSGLDPTVTGCUG
What is the function of this protein?
Involved in the control of reactive oxygen species levels and the regulation of mitochondrial redox homeostasis (PubMed:24601690).  Maintains thioredoxin in a reduced state.  May play a role in redox-regulated cell signaling.
What are the official names of this protein?
Thioredoxin reductase 2, mitochondrial, Selenoprotein Z, SelZ, TR-beta, Thioredoxin reductase TR3.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MCLN2_MOUSE
Sequence: MPGDEETLDLPAWNRVPDLTWGPHHRSAMASLDSEVREECLREDLKFYFMSPCEKYRARRQIPWKLGLQILKIVMVTTQLVRFGLSNQLVVAFKEDNTVAFKHLFLKGFSGVDEDDYSCSIYTQENTYESIFFAIKQYRHLKNISLATLGYGESEDNRTGLKVCKQHYKTGAMFSSNETLNIDSDIETDCIHLDLQVLTTEPEDWAQTSFFRLDFYRLVQVDISFALKGIDLQAVHSREIPDCYLFQNTITFDNTAHSGKIKIYLNSEANIEECKNMNISGSTQRSTHYLLVFDVFVIMICLASLILCTRSIVLALRLRKRFLNFFLEKYKQRVCGADQWEFVNGWYVLVTISDLMTIIGSILKMEIKAKKLTNYDVCSILLGTSTLFVWVGVIRYLGYFQTYNVLILTMQASLPKVLRFCACAGMIYLGYTFCGWIVLGPYHEKFENLNIVAECLFSLVNGDDMFATFAQIQQKSILVWLFSRLYLYSFISLFIYMVLSLFIALITDSYHTIKKYQQHGFPETDLQKFLKESGSKDGYQKQPSALLSCLCCLRRRRSNDHLILID
What is the function of this protein?
Nonselective cation channel probably playing a role in the regulation of membrane trafficking events.  Acts as Ca(2+)-permeable cation channel with inwardly rectifying activity (PubMed:19763610).  May activate ARF6 and be involved in the trafficking of GPI-anchored cargo proteins to the cell surface via the ARF6-regulated recycling pathway (By similarity).  May play a role in immune processes.  In adaptive immunity, TRPML2 and TRPML1 may play redundant roles in the function of the specialized lysosomes of B cells (PubMed:17050035).  In the innate immune response, may play a role in the regulation of chemokine secretion and macrophage migration (PubMed:26432893).  Through a possible and probably tissue-specific heteromerization with MCOLN1 may be at least in part involved in many lysosome-dependent cellular events.
What are the official names of this protein?
Mucolipin-2, Transient receptor potential channel mucolipin 2, TRPML2.
What is the protein family that this protein belongs to?
Belongs to the transient receptor (TC 1.A.4) family. Polycystin subfamily. MCOLN2 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein. Note=Localizes to recycling endosomes in activated macrophages and microglia.
Protein: CHED_METFK
Sequence: MANPIEEQLATNLYFDKTFNCEAAKILPGEYYTTNQDIVIVTVLGSCVSACIRDKVSGIGGMNHFMLPEGNPADANNPVSESARYGTYAMEVLINQLLKNGARRENLEAKIFGGGNVLSGFTAINIGEKNAAFVRKYLRDENIRVVGEDLNDIYPRKVYFFPRTGRVLVKKLKQMHNNTLISREESYAKRLKANKVAGEVELF
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: YRIB_ECOLI
Sequence: MVLNVVLAGDFDCVRRP
What are the official names of this protein?
Protein YriB.
Protein: DFB35_MOUSE
Sequence: MPQTFFVFCFLFFVFLQLFPGTGEIAVCETCRLGRGKCRRACIESEKIVGWCKLNFFCCRERI
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Beta-defensin 35, BD-35, mBD-35, Defensin, beta 35.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PP226_ARATH
Sequence: MSSLSRFLLRGNFSFSTHTNRRFFSAVTAAAATPSPPKPSLITLVNDERDPKFITEKFKKACQAEWFRKNIAVYERTVRRLAAAKKFEWVEEILEEQNKYPNMSKEGFVARIINLYGRVGMFENAQKVFDEMPERNCKRTALSFNALLNACVNSKKFDLVEGIFKELPGKLSIEPDVASYNTLIKGLCGKGSFTEAVALIDEIENKGLKPDHITFNILLHESYTKGKFEEGEQIWARMVEKNVKRDIRSYNARLLGLAMENKSEEMVSLFDKLKGNELKPDVFTFTAMIKGFVSEGKLDEAITWYKEIEKNGCRPLKFVFNSLLPAICKAGDLESAYELCKEIFAKRLLVDEAVLQEVVDALVKGSKQDEAEEIVELAKTNDYLQCKLRLFPKE
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At3g13160, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: QUEF_PROM5
Sequence: MSTPNLYDSTNKPLYGERLIEESKIICFDNPNKKRIYEISIELPEFTCKCPFSGYPDFAKLNIFYQPNSKVYELKSLKLYINHFRDLKISHEEVVNRIMDDLLNAAAPHWIHLNADFNPRGNVSMKLDIYSGQKRN
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROB_STAAR
Sequence: MKLQTTYPSNNYPIFVEHGAIDHISTYIDQFDQSFILIDEHVNQYFADKFNDILSYENVHKVIIPAGEKTKTFEQYQETLEYILSHHVTRNTAIIAVGGGATGDFAGFVAATLLRGVHFIQVPTTILAHDSSVGGKVGINSKQGKNLIGAFYRPTAVIYDLDFLKTLPFEQILSGYAEVYKHALLNGESATQDIEQHFKDREILQSLKGMDKYIAKGIETKLDIVVADEKEQGVRKFLNLGHTFGHAVEYYHKIPHGHAVMVGIIYQFIVANALFDSKHDINHYIQYLIQLGYPLDMITDLDFETLYQYMLSDKKNDKQGVQMVLIRQFGDIVVQHVDQLTLQHACEQLKTYFK
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.