PharMolix/UniProtQA huggingface dataset:
Protein: PAM17_EMENI
Sequence: MHTTLLSNSMRGAALCTRVSSTTLNPVTLQTSAIYQTISLKNQTRPSSTSTVRFLKASPTLRTSSARPQAQIATSCINAKNTISVRSNSTTSTSAREEAAKLDWNSYFKLRASRRRYTLASSIVSSAVSTVVGVQVLSSQNLENLGAQVMGLDPFVVLGMATAACGAVGWLVGPFLGNAVWGLVNRSYKKAFLVKEKEFFDRIKRYRVDPSSNSMTNPVPDYYGEKIGSVQGYRQWLKDQRAYNRKRRSFIK
What is the function of this protein?
Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
What are the official names of this protein?
Presequence translocated-associated motor subunit pam17, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PAM17 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TRUA_BURM9
Sequence: MMRIALGIQYDGAAFCGWQSQPHGKTVQDALERSLAEFAQTSLHTTVAGRTDTGVHGLGQVVHFDTDLDRADFSWVRGTNAFLPPTVAVQWAKPMPDTFHARFAAFERTYYYALYVHPVRSPMLAGRAGWVHTPLDVDAMREAAAHLVGEHDFSAFRSSECQAKSPVKHLYQIGIRPDGDFIHFRFRANAFLHHMVRNLMGCLVAVGRGRYPSSWLAEVLESRDRDCAAPTFMPEGLYLAHVGYPAEFAVPPAQLGSVPWSSVWADLDGRT
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: RL24_PSEA7
Sequence: MQKIRRDDEVIVIAGKDKGKRGKVLKVLADDRLVVGGVNLIKRHTKPNPMLGQQGGIVEKEAPLHVSNVAIFNTETSKADRVGFKVEDGKKIRVFKSTQKPVQA
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: UNG_ECO57
Sequence: MANELTWHDVLAEEKQQPYFLNTLQTVASERQSGVTIYPPQKDVFNAFRFTELGDVKVVILGQDPYHGPGQAHGLAFSVRPGIATPPSLLNMYKELENTIPGFTRPNHGYLESWARQGVLLLNTVLTVRAGQAHSHASLGWETFTDKVISLINQHREGVVFLLWGSHAQKKGAIIDKQRHHVLKAPHPSPLSAHRGFFGCNHFVLANQWLEQHGETPIDWMPVLPAESE
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_RICRO
Sequence: MQNIDLISEEEAQKLLEELADKIAAYNHAYYIEDNPLVSDSEYDQLFNTNLKLEQKFPHLILENSPSKKVGAKIANKFAKVTHQVPMLSLSNAFDEQDVRDFVDRIKIFLRLNEFAPIFCEPKIDGVSFSAVYKHGVLTTGATRGDGYVGEDITANIKTIKNFPHKIDNVPEFLEVRGEIYIEKQDFLNLNKEQEEQGKDKFANPRNAAAGSLRQLDSSITAKRPLKYFVYSGGVTEQNLASSQDQLLTKLKECGFNINEISKLASSEEEIFAFYEYLKTNRENLPYEIDGVVYKLNDFALQNRMGFIARNPRFATAHKFPAIIGQTKLLSITVQVGRTGTLTPVAELEPIEIGGVTVSRATLHNFQEIARKDLRIKDYVFLQRAGDVIPKIMGVDFDKRPNDTETFDTPLFCLSCNSKLHYTPEDIIIRCDNGLNCPAQNYERIRHFVSKNAMDIEGLGRKQVEFLIDKGLISNPLDIFFLKEKNDSSLAKLENMDGWGKKSVENLFKNIEKSKNVSLPRFIYALGIRHIGEQNAKLLAREFGSYNNFIAQMELLRTNEPDIYQKLNNLEGIGDKILVDIIDFFDVKENIELIKKLGEILNIEDYKETREQSSLTDKIVVFTGSLPTISRAEAKATAEKLGAKVAVGVSSNTDLVVAGVDAGSKLKKAKELNIKIIDEEEWLTLIKNV
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: EFG_STRP6
Sequence: MAREFSLAKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETHEGASQMDWMEQEQERGITITSAATTAQWDGHRVNIIDTPGHVDFTIEVQRSLRVLDGAVTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVQTLHDRLQANAHPIQLPIGAEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPEEYLEQAQEYREKLIEAVAETDEDLMMKYLEGEEITNDELIAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIAYLPSPLDIPAIKGVNPDTDAEEERPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVLNSGSYVMNTSKGKRERIGRILQMHANSRQEIETVYAGDIAAAVGLKDTTTGDSLTDEKAKVILESIEVPEPVIQLMVEPKSKADQDKMGVALQKLAEEDPTFRVETNVETGETVIAGMGELHLDVLVDRMKREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDVWIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLIESMANGVLAGYPMVDVKAKLYDGSYHDVDSSETAFKIAASLALKEAAKSAQPAILEPMMLVTITAPEDNLGDVMGHVTARRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSATQGRGTFMMVFDHYEDVPKSVQEEIIKKNKGE
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_SYNR3
Sequence: MLQYQIDRVDYQIADDQSQSGVFVIGPLDRGQATTLGTALRRVLMSGLEGTAVTAVRIAGVNHEYATVPGVREDVLDILLNCKELVLSSRSRDTEIGRLVVNGPASVTAGDLQFSSQVSVVNADCPIATVADGHALELEVHVERGVGYRPVERTSEDAAALDLLQIDAVFMPVRRVNFTVDETAVGEGGSARERLRLEINTNGSITPDDALAYAANQLIALFQPLATVTLAEEPGQEPEPSAESQIPLEELNLSVRAYNCLKRAQVNSVSDLMGFSYEDLLEIKNFGAKSADEVIEALERIGISLPQSRTTA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: DRG2_HUMAN
Sequence: MGILEKISEIEKEIARTQKNKATEYHLGLLKAKLAKYRAQLLEPSKSASSKGEGFDVMKSGDARVALIGFPSVGKSTFLSLMTSTASEAASYEFTTLTCIPGVIEYKGANIQLLDLPGIIEGAAQGKGRGRQVIAVARTADVIIMMLDATKGEVQRSLLEKELESVGIRLNKHKPNIYFKPKKGGGISFNSTVTLTQCSEKLVQLILHEYKIFNAEVLFREDCSPDEFIDVIVGNRVYMPCLYVYNKIDQISMEEVDRLARKPNSVVISCGMKLNLDYLLEMLWEYLALTCIYTKKRGQRPDFTDAIILRKGASVEHVCHRIHRSLASQFKYALVWGTSTKYSPQRVGLTHTMEHEDVIQIVKK
What is the function of this protein?
Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP.  When hydroxylated at C-3 of 'Lys-21' by JMJD7, may bind to RNA and play a role in translation.
What are the official names of this protein?
Developmentally-regulated GTP-binding protein 2, DRG-2, Translation factor GTPase DRG2, TRAFAC GTPase DRG2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: RS14_PEDPA
Sequence: MAKTSKIIKEQKIEETVARYAELRRELKANKDYRALSQLPRNASPTRMHRRDSLDGRPHAYMRKFGMSRLNFRRLAHEGQIPGVRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: TA2R8_PANPA
Sequence: MFSPADNIFIILITGEFILGILGNGYIALVNWIDWIKKKKISTVDYILTNLVIARICLISVMVVNGIVIVLNPDVYTKNKQQIVIFTFWTFANYLNMWITTCLNVFYFLKIASSSHPLFLWLKWKIDMVVHWILLGCFAISLLVSLIAAIVLSCDYRFHAIAKHKRNITEMFHVSKXPYFEPLTLFNLFAIVPFIVSLISFFLLVRSLWRHTKQIKLYATGSRDPSTEVHVRAIKTMTSFIFFFFLYFISSILMTFSYLMTKYKLAVEFGEIAAILYPLGHSLILIVLNNKLRQIFVRMLTCRKIACVI
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 8, T2R8.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HUTU_BACAA
Sequence: MEKVKQTIRAPRGTELQTKGWVQEAALRMLMNNLDPEVAEKPEELVVYGGIGRAARNWESYQAIVDSLKTLESDETLLVQSGKPVAIFKSHEDAPRVLLANSNLVPKWANWDHFRELEKKGLMMYGQMTAGSWIYIGTQGILQGTYETFGEAARQHFGGSLKGTLTLTAGLGGMGGAQPLAVTMNGGVVIAIDVDKRSIDRRIEKRYCDMYTESLEEALAVANEYKEKKEPISIGLLGNAAEILPELVKRNITPDLVTDQTSAHDPLNGYIPVGYTLEEAAKLREEDPERYVQLSKESMTKHVEAMLAMQEKGAITFDYGNNIRQVAFDEGLKNAFDFPGFVPAFIRPLFCEGKGPFRWVALSGDPEDIYKTDEVILREFADNEHLCNWIRMARQQVEFQGLPSRICWLGYGERAKFGRIINEMVANGELSAPIVIGRDHLDCGSVASPNRETEAMKDGSDSVADWPILNALINSVNGASWVSVHHGGGVGMGYSLHAGMVIVADGTEAAAKRIERVLTSDPGMGVVRHVDAGYDLAVETAKEKGVNIPMMK
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPR43_ARATH
Sequence: MSRELTVSLAAIASQALTFPQLNQIHAQLIVFNSLPRQSYWASRIISCCTRLRAPSYYTRLIFDSVTFPNVFVVNSMFKYFSKMDMANDVLRLYEQRSRCGIMPDAFSFPVVIKSAGRFGILFQALVEKLGFFKDPYVRNVIMDMYVKHESVESARKVFDQISQRKGSDWNVMISGYWKWGNKEEACKLFDMMPENDVVSWTVMITGFAKVKDLENARKYFDRMPEKSVVSWNAMLSGYAQNGFTEDALRLFNDMLRLGVRPNETTWVIVISACSFRADPSLTRSLVKLIDEKRVRLNCFVKTALLDMHAKCRDIQSARRIFNELGTQRNLVTWNAMISGYTRIGDMSSARQLFDTMPKRNVVSWNSLIAGYAHNGQAALAIEFFEDMIDYGDSKPDEVTMISVLSACGHMADLELGDCIVDYIRKNQIKLNDSGYRSLIFMYARGGNLWEAKRVFDEMKERDVVSYNTLFTAFAANGDGVETLNLLSKMKDEGIEPDRVTYTSVLTACNRAGLLKEGQRIFKSIRNPLADHYACMDLLR
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At1g14470.
What is the protein family that this protein belongs to?
Belongs to the PPR family. PCMP-A subfamily.
Protein: SCPB_STRPM
Sequence: MTYLSQIEALLFVAGEEGLSLRHLASMLSLTPTALQQQLEKLSQKYEKDQHSSLCLIETANTYRLVTKEGFAELLRAYAKTPMNQSLSRASLEVLSIVAYKQPITRIEIDDIRGVNSSGALSKLLAFDLIREAGKKDVVGRPHLYATTDYFLDYMGINHLDELIEVSAVEPADEEIALFRTQD
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein B.
What is the protein family that this protein belongs to?
Belongs to the ScpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: DER_BRUAB
Sequence: MGFTLAIVGRPNVGKSTLFNRLVGRKLALVDDLPGVTRDRRIHDAKLYDLKFQVIDTAGLEEAANDSLEARMRAQTEAAISEADAVLFVIDAKAGITPADSTFAEAVRRSGKPVVLVANKAEARGSEAGMYDAFQLGLGEPCPISAEHGQGMPDLRDAIVELLGEERVFAEERQEEAADEVFTPAAVGALVGDDIEDPDAEEIPAYDATKPLRIAIVGRPNAGKSTLINTMLGEDRLLTGPEAGITRDSISADWEWHGRKINLFDTAGMRRKARVQEKLEKLSVADSLRAIRFAEVVIIVLDATIPFEKQDLQIADLIIREGRAPVIAFNKWDLIEDRQMVLADLYEKTARLLPQVRGLRAVPISGERGQGIDKLMENVVKTHEIWNRRISTGRLNRWLEGVIAHQPPPAVSGRRLKVKYMTQVKTRPPGFVVSCSRPDAMPQSYVRYLINGLRETFDMPGVPIRLSLRTSDNPFAGRAKKKK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: NDUA7_BOVIN
Sequence: MASATRFIQWLRNWASGRDLQAKLQLRYQEISKRTQPPPKLPVGPSHKLSNNYYCTRDGRREAMPPSIVMSSQKVLVAGKPAESSAVAASEKKAVSPAPPIKRWELSQDEPYL
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7, Complex I-B14.5a, CI-B14.5a, NADH-ubiquinone oxidoreductase subunit B14.5a.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFA7 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: SYS_NEIG1
Sequence: MLDIQLLRSNTAAVAERLARRGYDFDTARFDALEERRKSVQVKTEELQASRNSISKQIGALKGQGKHEEAQAAMDQVAQIKTDLEQAAADLDAVQKELDAWLLSIPNLPHESVPPGKDETENVEVRKVGTPREFDFEIKDHVDLGEPLGLDFEGGAKLSGARFTVMRGQIARLHRALAQFMLDTHMLQHGYTEHYTPYIVDDTTLQGTGQLPKFAEDLFHVTRGGDETKTTQYLIPTAEVTLTNTVAGSIIPSEQLPLKLTAHSPCFRSEAGSYGKDTRGLIRQHQFDKVEMVQIVHPEKSYGALEEMVGHAENILKALELPYRVITLCTGDMGFSAAKTYDLEVWVPAQNTYREISSCSNCEDFQARRMKARFKDENGKNRLVHTLNGSGLAVGRTLVAVLENHQNADGSINIPAALQPYMGGVTKLEVK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGC_AKKM8
Sequence: MKQVQVAVVGASGYTGQELLRILLNHRGVKLVCATSRQYAGQPLWEVFPRFRQVPGSGLKFTDSDVEAIAATGAEVAFLALPHGVAASYARGLVDRGVRVIDLSADFRLDSPDVYEEYYGNPHPDTALMQEAVYGLPEWRREEIARARIVASPGCYPTSILLPLIPLFRAGMLEPEDVVACSGSGVSGAGRKASIPLLFCECNESFHAYGVPKHRHLSEIEQELSHAAGETVVMSFTPHLIPVNTGICSTITAKVKKGADPESVGRLLEEAYAAAPFVRLLGRNQPADTKNVTRTNCVDIGWAYDPRTNRVILMSAEDNVVKGAGGQAVQSFNIMCGFDETEGLWVL
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSRA_TOLAT
Sequence: MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKDVSVHREEIYMRIQSEKDNENGPQSY
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KGX19_CENTE
Sequence: DRDSCIDKSRCSKYGYYQECQDCCKKAGHNRGTCMFFKCKCA
What is the function of this protein?
Blocks human voltage-gated potassium channel Kv11. 1/KCNH2/ERG1 (IC(50)=16. 9 nM).
What are the official names of this protein?
Potassium channel gamma toxin gamma-KTx 1.9, Toxin II.10.9.
What is the protein family that this protein belongs to?
Belongs to the ergtoxin family. Gamma-KTx 1 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HEMH_BOVIN
Sequence: MAAALRSAGVLLRDRLLYGGSRACQPRRCQSGAATAAAATETAQRARSPKPQAQPGNRKPRTGILMLNMGGPETVEEVQDFLQRLFLDQDLMTLPVQDKLGPFIAKRRTPKIQEQYRRIGGGSPIKMWTSKQGEGMVKLLDELSPHTAPHKYYIGFRYVHPLTEEAIEEMERDGLERAVAFTQYPQYSCSTTGSSLNAIYRYYNEVGRKPTMKWSTIDRWPTHPLLIQCFADHILKELDHFPPEKRREVVILFSAHSLPMSVVNRGDPYPQEVGATVQRVMDKLGYSNPYRLVWQSKVGPMPWLGPQTDEAIKGLCKRGRKNILLVPIAFTSDHIETLYELDIEYSQVLASECGLENIRRAESLNGNPLFSKALADLVHSHLQSKERCSTQLTLSCPLCVNPTCRETKSFFTSQQL
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, mitochondrial, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: RPOZ_SHESH
Sequence: MARVTVEDAVNQIGNRFDMILVAARRARQIAVQGKDPMVEEENDKPTVIALREIELGLVTADTLDADERQTVREREAAEIAAVAAIAEGRNNVI
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: PUR5_BACCN
Sequence: MANAYKQAGVDIEAGYEAVSRMKKHVQTTMRKEVLGGLGGFGGMFDLSKLPLEEPVLVSGTDGVGTKLMLAFMADKHDTIGIDAVAMCVNDIVVQGAEPLFFLDYIACGKADPSKIEHIVKGIAEGCRQAGCSLIGGETAEMPGMYSKEEYDLAGFTVGIVDKKKIITGHSLDEGHVLIGLASSGIHSNGYSLVRKVLLEDGQMSLDRIYGRLELPLGEELLKPTKIYVKPILELLKKYEVYGMAHITGGGFIENIPRMLPKGIGAEIDLGSWNIQPIFSLIQEVGKIEEKEMFNIFNMGIGMVVAVKEENAKAVVRLLEEQGEKAYIIGRTVKGSGVAFNGGIDHE
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAS2B_THET2
Sequence: MGKRLYAVAYDIPDDTRRVKLANLLKSYGERVQLSVFECYLDERLLEDLRRRARRLLDLGQDALRIYPVAGQVEVLGVGPLPELREVQVL
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Involved in the integration of spacer DNA into the CRISPR cassette (By similarity).  Functions as a dsDNA endonuclease and as a weak ssRNase (PubMed:22942283).
What are the official names of this protein?
CRISPR-associated endonuclease Cas2 2.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Protein: ZBED6_HUMAN
Sequence: MSVCTLSVPVSSLSPGRRCNTFSDSGILGCVPINSNTDEEDVVEEKMVAEGVNKEAKQPAKKKRKKGLRIKGKRRRKKLILAKKFSKDLGSGRPVADAPALLASNDPEQDEESLFESNIEKQIYLPSTRAKTSIVWHFFHVDPQYTWRAICNLCEKSVSRGKPGSHLGTSTLQRHLQARHSPHWTRANKFGVASGEEDFTLDVSLSPSSGSNGSFEYIPTDPLDDNRMGKKHDKSASDALRAERGRFLIKSNIVKHALIPGTRAKTSAVWNFFYTDPQHISRAVCNICKRSVSRGRPGSHLGTSTLQRHLQATHPIHWAVANKDSGAVANGLDEAETERSDLLSDTLHGEKSTGSQDLTAEDLSDSDSDEPMLEVENRSESPIPVAEQGTLMRAQERETTCCGNPVSSHISQAIIQMIVEDMHPYNYFSTPAFQRFMQIVAPDYRLPSETYFFTKAVPQLYDCVREKIFLTLENVQSQKIHLTVDIWTHDPSTDYFIVTVHWVSLETASFLNNGRIPDFRKWAVLCVTGLAKDCLITNILQELNDQIGLWLSPNFLIPSFIVSDNSSNVVHAIKDGGFTHVPCFLHCLNMVIQDFFCEHKSIENMLVAARKTCHHFSHSVKARQILQEFQNDHQLPWKNLKQDETGHWISTFYMLKWLLEHCYSVHHSLGRASGVVLTSLQWTLMTYVCDILKPFEEATQKVSVKTAGLNQVLPLIHHLLLSLQKLREDFQVRGITQALNLVDSLSLKLETDTLLSAMLKSKPCILATLLDPCFKNSLEDFFPQGADLETYKQFLAEEVCNYMESSPEICQIPTSEASCPSVTVGADSFTSSLKEGTSSSGSVDSSAVDNVALGSKSFMFPSAVAVVDEYFKEKYSEFSGGDDPLIYWQRKISIWPALTQVAIQYLSCPMCSWQSECIFTKNSHFHPKQIMSLDFDNIEQLMFLKMNLKNVNYDYSTLVLSWDPEQNEVVQSSEKEILP
What is the function of this protein?
Transcriptional repressor which binds to the consensus sequence 5'-GCTCGC-3', transcription regulation may be tissue-specific (By similarity).  Regulates the expression of target genes such as: IGF2, PGAP6/TMEM8, ENHO, and PIANP (By similarity).  Acts as a transcriptional repressor of growth factor IGF2, thereby negatively regulating postnatal growth of muscles and internal organs, especially in females (By similarity).  Negatively regulates myoblast differentiation and myoblast mitochondrial activity via its regulation of IGF2 transcription (By similarity).  Negatively regulates the cell cycle of myoblasts, potentially via transcriptional regulation of the E2F family of transcription factors such as: E2F1 and E2F2 (By similarity).  Positively regulates the cell cycle and survival of pancreatic beta cells (PubMed:24043816).  Binds to the CDH2 gene and may directly repress CDH2 transcription (By similarity).  Probably by controlling CDH2 expression, regulates pancreatic beta cell adhesion, and formation of cell-to-cell junctions between pancreatic beta cells and neural crest stem cells (By similarity).  May also play a role in embryonic beta cell differentiation (By similarity).  May play a role in insulin sensitivity and glucose clearance (By similarity).
What are the official names of this protein?
Zinc finger BED domain-containing protein 6.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Cytoplasm. Note=Located predominantly in the nucleolus but is also dispersed throughout the nucleus (By similarity). Mainly cytoplasmic in insulin- and glucagon-positive islet pancreatic cells, however nuclear localization is evidence in some pancreatic endocrine cells (PubMed:24043816).
Protein: TUPC_PEPAC
Sequence: MQITVSNLKKSYGGSTVLDVESLTFESGKITGIIGPNGAGKTTLLNIISGIDMDFEGDVEYSGSDYSEVKRDITMVFQKGGLLKRSVFENIAYPLKLRGTDKNEIQQTVVELMRHLGIEELSSKKAHKLSGGETQRVALARALAIKPRALLLDEPTASIDPEYMETIEKCIVDYNRKSKATILIITHSMDQARRLCDNIVFLESGRVGEADGFF
What is the function of this protein?
Part of an ABC transporter complex involved in tungstate uptake.  Probably responsible for energy coupling to the transport system.
What are the official names of this protein?
Tungstate uptake system ATP-binding protein TupC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: CAP3C_STREE
Sequence: MKKVKKAVIPAAGLGTRFLPATKALAKEMLPIVDRPTIHFVIEEALRSGIEDILVVTGKSKRSIEDYFDSTFELEYSLRKQGKMELLKSVNESTDIKVHFVRQSSPRGLGDAVLQAKSFVGDDPFVVMLGDDLMDITDSTAVPLTRQLMDDYNATQASTIAVMPVRYEDVSSYGVISPRLESSNGLYSVDAFVEKPKPEEAPSNLAIIGRYLLTPEIFSILETQKPGAGNEIQLTDAIDTLNKTQSVFAREFVGKRYDVGDKFNFMKTSIDYALQHPQIKESLKNYVIALGKQLEKLDDCSSSGHL
What are the official names of this protein?
UTP--glucose-1-phosphate uridylyltransferase, Alpha-D-glucosyl-1-phosphate uridylyltransferase, UDP-glucose pyrophosphorylase, UDPGP, Uridine diphosphoglucose pyrophosphorylase.
What is the protein family that this protein belongs to?
Belongs to the UDPGP type 2 family.