PharMolix/UniProtQA huggingface dataset:
Protein: TRX1_HHV14
Sequence: MKTNPLPATPSVWGGSTVELPPTTRDTAGQGLLRRVLRPPISRRDGPVLPRGSGPRRAASTLWLLGLDGTDAPPGALTPNDDTEQALDKILRGTMRGGAALIGSPRHHLTRQVILTDLCQPNADRAGTLLLALRHPADLPHLAHQRAPPGRQTERLGEAWGQLMEATALGSGRAESGCTRAGLVSFNFLVAACAASYDARDAADAVRAHVTANYRGTRVGARLDRFSECLRAMVHTHVFPHEVMRFFGGLVSWVTQDELASVTAVCAGPQEAAHTGHPGRPRSAVILPACAFVDLDAELGLGGPGAAFLYLVLTYRQRRDQELCCVYVIKSQLPPRGLEPALERLFGRLRITNTIHGTEDMTPPAPNRNPDFPLAGLAANPQTPRCSAGQVTNPQFADRLYRWQPDLRGRPTARTCTYAAFAELGMMPEDSPRCLHRTERFGAVTVPVVILEGVVWCPGEWRACA
What is the function of this protein?
Structural component of the T=16 icosahedral capsid.  The capsid is composed of pentamers and hexamers of major capsid protein/MCP, which are linked together by heterotrimers called triplexes.  These triplexes are formed by a single molecule of triplex protein 1/TRX1 and two copies of triplex protein 2/TRX2.  Additionally, TRX1 is required for efficient transport of TRX2 to the nucleus, which is the site of capsid assembly.
What are the official names of this protein?
Triplex capsid protein 1.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae TRX1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: ISPE_RUTMC
Sequence: MSSTWLAPAKINLFLHINNKREDGYHNLQTIFQMLDYYDELKFSITNGGVIKRINGNEDVEQSQDLIVKAAKVLQEYTGTTLGANLSIVKNIPIGGGLGGGSSDAATTLVALNQLWDTKLTQPQLMKLGLNLGADVPVFIFAKSAWAEGIGEILSPIKMPNYYYLVVFINKHTSTKEIFSHYALTMSKPQGKIAKFSELINTHNDCLQAAIALEAEIGVALKHLNTCANHISQVRMSGTGSCVFNEFLTEKDALAAAKKVPKKWMSFVTRAINTSPIHSWAVAKR
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: CLASR_RAT
Sequence: MWHEARKHERKLRGMMVDYKKRAERRREYYEKIKKDPAQFLQVHGRACKVHLDSAVALAAESPVNMMPWQGDTNNMIDRFDVRAHLDHIPDYTPPLLTTISPEQESDERKCNYERYRGLVQNDFAGISEEQCLYQIYIDELYGGLQRPSEDEKKKLAEKKASIGYTYEDSTVAEVEKVAEKPEEEESPAEEESNSDEDEVIPDIDVEVDVDELNQEQVADLNKQATTYGMADGDFVRMLRKDKEEAEAIKHAKALEEEKAMYSGRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPSPGREEKITFITSFGGSDEEAAAAAAAAAASGAAPGKPPAPPQPGGPAPGRNASARRRSSSSSASRTSSSRSSSRSSSRSRRGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSDGGSRDGHRYSRSPARRSGYAPRRRSRSRSRSGDRYKRGARGPRHHSSSHSRSSWSLSPSRSRSLTRSGSRSQSRSRSRSQSHSQSQSHSPSPPREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQERLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSRSPHYRH
What is the function of this protein?
Probably functions as an alternative splicing regulator.  May regulate the mRNA splicing of genes such as CLK1.  May act by regulating members of the CLK kinase family (By similarity).
What are the official names of this protein?
CLK4-associating serine/arginine rich protein, Splicing factor, arginine/serine-rich 16.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DNLJ_BURMA
Sequence: MARSPVEPPASQPAKRAAWLRAELERANYAYYVLDQPDLPDAEYDRLFVELQRIEAEHPDLVTPDSPTQRVGGEAASGFTPVVHDKPMLSLNNGFADEDVIAFDKRVADGLDKATDLAGTVTEPVEYACELKFDGLAISLRYENGRFVQASTRGDGTTGEDVTENIRTIRAIPLTLKGKRIPRMLDVRGEVLMFKRDFARLNERQRAAGQREFANPRNAAAGSLRQLDSKITASRPLSFFAYGIGVLDGADMPDTHSGLLDWYETLGLPVNRERAVVRGAAGLLAFFHSVGERRESLPYDIDGVVYKVNRRDEQDRLGFVSRAPRFALAHKFPAQEALTKLTAIDVQVGRTGAITPVARLEPVFVGGATVTNATLHNEDEVRRKDIRIGDTVIVRRAGDVIPEVVSAVLDRRPADAQEFVMPTECPECGSRIERLPDEAIARCTGGLFCPAQRKQALWHFAQRRALDIDGLGEKIIDQLVEQNLVRTPADLFNLGFSTLVALDRFAEKSARNLIDSLEKAKHTTLARFIYALGIRHVGESTAKDLAKHFGSLDPIMDAPIDALLEVNDVGPIVAESIHQFFAEEHNRTVIEQLRARGKVTWPEGPPAPRAPQGVLAGKTVVLTGTLPTLTREAAKEMLEAAGAKVAGSVSKKTDYVVAGADAGSKLAKAEELGIPVLDEAGMHTLLEGHAR
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: NUSB_LACPL
Sequence: MSLTRHEIREKAFQALFALNANPDADENQLFQQLLNPEETDAVEIPAYLSTLVTGVREHQVELDAQIQPYLSQKWSLDRLAKTDLIILRIAFFELQFVDDVPTKVAVNEAIELTKAFSDDRSRKFVSGVLGKVVKNQAN
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: CYB_EUBJA
Sequence: MTNIRKTHPLMKIINDAFIDLPTPSNISSWWNFGSLLGLCLIMQILTGLFLAMHYTPDTTTAFSSITHICRDVNYGWIIRYLHANGASMFFICLYAHMGRGLYYGSYAFQETWNIGVILLFTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGNTLVEWIWGGFSVDKATLTRFFAFHFILPFIILALAIVHLLFLHETGSNNPTGIPSNMDKIPFHPYYTIKDILGALLLILTLLMLTLFAPDLLGDPDNYTPANPLSTPAHIKPEWYFLFAYAILRSIPNKLGGVLALLLSILILAFIPMLHTSKQRSMMFRPFSQFLFWVLVADLLTLTWIGGQPVEHPYVIVGQFASILYFLLILVLMPTASLIENKLMKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: HIS8_DEHMB
Sequence: MTYNLKKYIRTDLEDFDGYSACKAPELVKTSKQIIKLDANENLYGAAPTVRQAMSEFNQYHIYPDATQSEIRRLLSEYTGVAVEQIVCGAGSDQLIDLLLRLFINPGDEVINCPPTFAMYKFYTELNRGKIVNVPRDASYNINIAAINNAITPQTKLIFIAAPNNPTGTAISKEEIRQILDLGVPTVVDEAYYEFTGQTMVSDMSKYPNLMILRTFSKWAGLAGLRVGYGLFPPIIADYLSRIKDPYSVNIAADAAVRQTMLQREYMLETVKKIVNERQRLYTELSKFGWLKPYPSVANFILCKLLKGKAKEVQHELESKGILVRCFDAPMMENCLRFSVGKPEDTDGLLKALGEMGE
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: RS21_HAEIE
Sequence: MPVIKVRENESFDVALRRFKRSCEKAGILAEVRAREFYEKPTTIRKRENATLAKRHAKRNARENARNTRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: TPMT_NITEC
Sequence: MEHEFWLQSWHEGRTGFHQLRVQPLLQKYWPTLDLPTGSKIFVPLTGKSLDMAWLAAQGYRVLGVELSLLAVQQFFAEHGLKPAVRESHYGTHYTARNIEVICGDTFALDAALLSDCSGIYDRAALIALPPELRVPYINELMTCLPAGCSGLLITLEYQQQEMVGPPFSVEEAEVLKCYSPRWCVKLLERNDILPQEPGFAARGLTKLATAVYQLQRLAV
What are the official names of this protein?
Thiopurine S-methyltransferase, Thiopurine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y277_GRABC
Sequence: MSIWRSVENGITLALRVVPKARKIGLGGTVPGADGKPRLKISVSAPADKGQANEAVRDMLAKALRVPASRITLLQGLTARDKLVRVEGDPETLGSTVETLASGGTDS
What are the official names of this protein?
UPF0235 protein GbCGDNIH1_0277.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: APBC_ECOLI
Sequence: MNEQSQAKSPEALRAMVAGTLANFQHPTLKHNLTTLKALHHVAWMDDTLHVELVMPFVWHSAFEELKEQCSAELLRITGAKAIDWKLSHNIATLKRVKNQPGINGVKNIIAVSSGKGGVGKSSTAVNLALALAAEGAKVGILDADIYGPSIPTMLGAENQRPTSPDGTHMAPIMSHGLATNSIGYLVTDDNAMVWRGPMASKALMQMLQETLWPDLDYLVLDMPPGTGDIQLTLAQNIPVTGAVVVTTPQDIALIDAKKGIVMFEKVEVPVLGIVENMSVHICSNCGHHEPIFGTGGAEKLAEKYHTQLLGQMPLHISLREDLDKGTPTVISRPESEFTAIYRQLADRVAAQLYWQGEVIPGEISFRAV
What is the function of this protein?
Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins.  Can hydrolyze ATP.
What are the official names of this protein?
Iron-sulfur cluster carrier protein.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family.
Protein: HBAA_CHENI
Sequence: MVLTAGDKANVKTVWSKVGSHLEEYGSETLERLFIVYPSTKTYFPHFDLHHDSAQVRAHGRKVLSALGEAVNHIDDIPGALSKLSDLHAQTLRVDPVNFKLLNLCFVVVVGRHHPTILTPEVHVSLDKFLSAVATALTSKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-A, Alpha-A-globin, Hemoglobin alpha-A chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: GCS21_MYCSJ
Sequence: MLSVPASSRIDFAGSPRPTVGVEWEFALVDAHTRDLSNEAATVIAEIGETPHVHKELLRNTVEVVTGICENTGEAMADLHDTLQVVRRIVRDRGMELFCAGTHPFANWSTQQLTDAPRYAELIKRTQWWGRQMLIWGVHVHVGISSAHKVMPIISSLLNQYPHLLALSASSPYWDGSDTGYASNRAMMFQQLPTAGLPFQFQSWPEFERFVHDQKKTGIIDHMNEIRWDIRPSPHLGTVEIRVFDGVSNIAELGSLVALTHCLVVDLDRRLDAGEQLPVMPPWHVQENKWRAARYGLDAEIILDADSNERLVTEDLDDLLTRLQPVARSLDCADELAGVAEIYRHGASYQRQRRVAEEHDGDLLAVVDALVAELEL
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2-1, Gamma-glutamylcysteine synthetase 2-1, GCS 2-1, Gamma-GCS 2-1.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: PA2HB_BOTLC
Sequence: SLFELGKMILQETGKNSVKSYGVYGCNCGVGGRGKPKDATDRCCYVHKCCYKKLTGCDPKKDRYSYSWKDKTIVCGENNPCLKELCECDKAVAICLRENLGTYNKKYRYHLKPFCKKADPC
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) homolog that lacks enzymatic activity (By similarity).  Shows myotoxic and edema-inducing activities in vivo (By similarity).  A model of myotoxic mechanism has been proposed: an apo Lys49-PLA2 is activated by the entrance of a hydrophobic molecule (e. g.  fatty acid) at the hydrophobic channel of the protein leading to a reorientation of a monomer (By similarity).  This reorientation causes a transition between 'inactive' to 'active' states, causing alignment of C-terminal and membrane-docking sites (MDoS) side-by-side and putting the membrane-disruption sites (MDiS) in the same plane, exposed to solvent and in a symmetric position for both monomers (By similarity).  The MDoS region stabilizes the toxin on membrane by the interaction of charged residues with phospholipid head groups (By similarity).  Subsequently, the MDiS region destabilizes the membrane with penetration of hydrophobic residues (By similarity).  This insertion causes a disorganization of the membrane, allowing an uncontrolled influx of ions (i. e.  calcium and sodium), and eventually triggering irreversible intracellular alterations and cell death (By similarity).
What are the official names of this protein?
Basic phospholipase A2 homolog blK-PLA2, svPLA2 homolog.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. K49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS10_CLOB1
Sequence: MAKQKIRIRLKAFDHSLLDQSALKIVETAKTTGAKVAGPVPLPTEKDIVTILRAPHKYKDAREQFEIRTHKRLIDIISPSPKTVDALMRLDLPAGVDIEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: CYH4_HUMAN
Sequence: MDLCHPEPAELSSGETEELQRIKWHRKQLLEDIQKLKDEIADVFAQIDCFESAEESRMAQKEKELCIGRKKFNMDPAKGIQYFIEHKLLTPDVQDIARFLYKGEGLNKTAIGTYLGERDPINLQVLQAFVDCHEFANLNLVQALRQFLWSFRLPGEAQKIDRMMEAFATRYCLCNPGVFQSTDTCYVLSFSIIMLNTSLHNPNVRDRPPFERFVSMNRGINNGSDLPEDQLRNLFDSIKSEPFSIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEFTTDKEPRGIIPLENLSVQKVDDPKKPFCLELYNPSCRGQKIKACKTDGDGRVVEGKHESYRISATSAEERDQWIESIRASITRVPFYDLVSTRKKKIASKQ
What is the function of this protein?
Promotes guanine-nucleotide exchange on ARF1 and ARF5.  Promotes the activation of ARF factors through replacement of GDP with GTP.
What are the official names of this protein?
Cytohesin-4, PH, SEC7 and coiled-coil domain-containing protein 4.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HIR1_YARLI
Sequence: MYIVKPSWLCHSDDQKKFEVYSVTVSPDNQRVATGGQDGKVRIWSAQSIRDSAKGDNESSDTPSNLSGAPAPGAKQLCSMATHNGAVTVVRFSPDGRYLATGSDDRVVLVWERDSTKVPRKEFGSSGEADTESWIVRKRLAAHDNDIQDLAWAPDSSILVTVGLDSGVIVWSGTTFEKIQRLDAHNSHVKGITFDPANKFFATASDDRTVQIFRYNRASATDVTFSTEATITSPFKQSPLSTYFRRCSWSPDGNHIAAANATNGPVSVVAIINRGTWDSDISLIGHEAPCEVAAFCPRIFARTKEAAEKKDKKSSSEKDKESDVIDVDAEPKVPESVPITVIASAGQDKTLTIWNTSNPRPVVVCHDMALKTITDLAWSQDGMSLFATSLDGSISYVQFEEGELGYVVSMEENESRLTRYGGGKEAAQIPESVEQLVLEEKVEAKEVKDSEKRMEELMGAAGAGSKAIASGATVIPSPASTVAAAAAAPVTTTARATTPLTAATSNPSTPAKPAKQKVTITKDGRKRVAPQLLTTTSSSVQGTLPAATTSSAAVPVASATAETIPVNDFSKPSYALPKGGVSTLVIGSKRRSDDLEDGSNGIQTALKKTRPDDDVPEYIAPVVVSPATTTSQVRLGAPKVRNLLMRSMTVRDAEKPRMANESVSLANGENTSSSSAPHSFNFEVRNGSGNDQTPTKVSVTRNSQVVFVDFVPYYVHLIAGNGCYFWATSAEDGSIVVYSPNGRRMLPPLVTGAPLSFLESQNEYLLAISSVGMLYLWNVVDKKAVFPPVSLAPILDSGSRYEDGGVLRGPHVTQCGVTGSGRVIITLSTGCGYTYDEGLRSWCRLSEPWWATGSQYWSATQLLGDESAKSRWVLAVEERTAEEAQRRAGGRGRYLKQLTRATLNREGYEGMEGVVSIAHLENRIAAAEMLESKHELRTFIIMYARRIAEEGLRSRVDELCRELLGPGKSQDSTWSPTVCGLDKHELLKEVVLKIGKYRESQRVAVVYGQAIGLLEDEVLGVASSSKSAASKGSKDKEDNEEEDGDHDMTDFKDAMSEQ
What is the function of this protein?
Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.
What are the official names of this protein?
Protein HIR1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat HIR1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TENA_HALH5
Sequence: MSFAASLYEKAQPIWEAGYNHPFVQGIGDGSLEKSKFQFFMKQDYLYLIDYARLFALGTLKGNDLQTMSTFSKLLHATLNVEMDLHRAYAKRLGISAEELEAIEPAATTLAYTSYMLNVAQRGSLLDLIAAVLPCTWSYYEIGVKLKGIPGASDHPFYGEWIKLYASDEFKELADWLIQMLDEEAKGLSSKEKAKLETIFLTTSRLENEFWDMAYNERMWNYNG
What is the function of this protein?
Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.  Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2-methylpyrimidine (HMP).  To a lesser extent, is also able to catalyze the hydrolytic cleavage of thiamine; however, this thiaminase activity is unlikely to be physiologically relevant.  Therefore, is involved in the regeneration of the thiamine pyrimidine from thiamine degraded products present in the environment, rather than in thiamine degradation.
What are the official names of this protein?
Aminopyrimidine aminohydrolase, 4-amino-5-aminomethyl-2-methylpyrimidine hydrolase.
What is the protein family that this protein belongs to?
Belongs to the TenA family.
Protein: SFH12_ARATH
Sequence: MTLIQDAELKPRMGSFKKRSSSKNLRYSMTKRRRSSKVMSVEIIEDVHDAEELKAVDAFRQSLILDELLPEKHDDYHMMLRFLKARKFDLEKTKQMWTEMLRWRKEFGADTVMEEFDFKEIDEVLKYYPQGHHGVDKEGRPVYIERLGLVDSTKLMQVTTMDRYVNYHVMEFERTFNVKFPACSIAAKKHIDQSTTILDVQGVGLKNFNKAARDLITRLQKVDGDNYPETLNRMFIINAGSGFRMLWNTVKSFLDPKTTAKIHVLGNKYQSKLLEIIDESELPEFLGGSCTCADNGGCMRSDKGPWKNPEIMKRVHNGDHKCSKGSQAENSGEKTIPEEDDSTTEPASEEEKASKEVEIVPAAHPAWNMPEAHKFSLSKKEVYAIQEACNNATTEGGRSPIFTGVMALVMGVVTMIKVTKNVPRKLTESTLYSSPVYCDDASMNKSAMQSEKMTVPAISGEDFMAIMKRMAELEQKVTVLSAQPTVMPPDKEEMLNAAISRSNVLEQELAATKKALDDSLGRQEELVAYIEKKKKKKKLFNYW
What is the function of this protein?
Required for transport of secretory proteins from the Golgi complex (By similarity).  Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro.
What are the official names of this protein?
Phosphatidylinositol/phosphatidylcholine transfer protein SFH12, Protein SEC FOURTEEN HOMOLOGS 12, AtSFH12.
What is the protein family that this protein belongs to?
Belongs to the SFH family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein.
Protein: MRAY_SALDC
Sequence: MLVWLAEHLVKYYSGFNVFSYLTFRAIVSLLTALFISLWMGPRMIARLQKLSFGQVVRNDGPESHFSKRGTPTMGGIMILTSIVISVLLWAYPSNPYVWCVLVVLIGYGIIGFVDDYRKVVRKDTKGLIARWKYFWMSVIALGVAFALYLVGKDTPATQLVVPFFKDVMPQLGLFYILLSYFVIVGTGNAVNLTDGLDGLAIMPTVFVAAGFALVAWATGNMNFANYLHIPYLRHAGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGIIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISLMLVLIGLATLKVR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: V237_FOWPN
Sequence: MSSLKYANTDITIKMVIITPKVLEDDSLSESSIHFANNRFHFDLYYIKPWAFVSILYLFLCFLYNII
What are the official names of this protein?
Uncharacterized protein FPV237, BamHI-ORF9.
Protein: PIMT_THIDA
Sequence: MAETLNPRAGIGMTSARTRGRMVERLREQGIKDEMVLAAMGMVPRHLYVDQALESRAYEDTALPIGFGQTISNPYIVARMAELARHGENGKGQTLGRVLEIGLGCGYQAAVLGKLAREVVSIERIAALVGKTRARLRELRVNNVKPKHGDGMNGARDFAPFDAIVLAAAFAEVPQALLAQLADGGRLVMPLGNATQTLCLIERQGEAFVEQRLEGVKFVPLLPGVA
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FXYD4_HUMAN
Sequence: MERVTLALLLLAGLTALEANDPFANKDDPFYYDWKNLQLSGLICGGLLAIAGIAAVLSGKCKCKSSQKQHSPVPEKAIPLITPGSATTC
What are the official names of this protein?
FXYD domain-containing ion transport regulator 4.
What is the protein family that this protein belongs to?
Belongs to the FXYD family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: AHPF_PSEAE
Sequence: MLDANLKTQLKAYLEKVSQPFEIVASLDDSDKSRELLGLLQDIVGLTDKITLKTDGSDARKPSFSLNRPGADIGLRFAGIPMGHEFTSLVLALLQVGGHPSKLDADVIEQVKGIEGTFEFETYFSLSCQNCPDVVQALNLMAVLNPNIRHVAIDGALFQDEVEARQIMSVPSIYLNGEVFGQGRMGVEEILAKIDTGAAARDAEKLTARDAFDVLVVGGGPAGAAAAIYAARKGIRTGVAAERFGGQVLDTMAIENFISVQETEGPKLARALEEHVRHYEVDIMNLQRASKLVPAKNAGELHEVRFESGGSLKAKTLILATGARWREMGVPGEQEYKAKGVCFCPHCDGPLFKGKRVAVIGGGNSGVEAAIDLAGIVAHVTLLEFDSKLRADAVLQRKLYSLPNVEVITSALTSEVKGDGQKVTGLVYKDRNSEEFKSIELEGIFVQIGLLPNTEWLKGSVELSPRGEIIVDARGETSLPGIFAAGDVTTVPYKQIVIAVGEGAKASLSAFDHLIRTSAPE
What is the function of this protein?
Serves to protect the cell against DNA damage by alkyl hydroperoxides.  It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein (By similarity).
What are the official names of this protein?
Alkyl hydroperoxide reductase subunit F.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
Protein: PA21B_PIG
Sequence: MKFLVLAVLLTVGAAQEGISSRALWQFRSMIKCAIPGSHPLMDFNNYGCYCGLGGSGTPVDELDRCCETHDNCYRDAKNLDSCKFLVDNPYTESYSYSCSNTEITCNSKNNACEAFICNCDRNAAICFSKAPYNKEHKNLDTKKYC
What is the function of this protein?
Secretory calcium-dependent phospholipase A2 that primarily targets dietary phospholipids in the intestinal tract (PubMed:17603006).  Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity) with preference for phosphatidylethanolamines and phosphatidylglycerols over phosphatidylcholines (By similarity).  May play a role in the biosynthesis of N-acyl ethanolamines that regulate energy metabolism and inflammation in the intestinal tract.  Hydrolyzes N-acyl phosphatidylethanolamines to N-acyl lysophosphatidylethanolamines, which are further cleaved by a lysophospholipase D to release N-acyl ethanolamines (By similarity).  May act in an autocrine and paracrine manner (By similarity).  Has anti-helminth activity in a process regulated by gut microbiota.  Upon helminth infection of intestinal epithelia, directly affects phosphatidylethanolamine contents in the membrane of helminth larvae, likely controlling an array of phospholipid-mediated cellular processes such as membrane fusion and cell division while providing for better immune recognition, ultimately reducing larvae integrity and infectivity (By similarity).
What are the official names of this protein?
Phospholipase A2, major isoenzyme, Group IB phospholipase A2, Phosphatidylcholine 2-acylhydrolase 1B.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted from pancreatic acinar cells in its inactive form.
Protein: CLPX_RICCN
Sequence: MVVEADKKALICSFCSKKQHEVKKLIAGPAVFICDECIDLCTDIMKEENKVALKQITSSIPTPQKICGILNDYVVGQDQAKKILAVAVYNHYKRLEYVQSGNNDVELNKSNILLIGPTGSGKTLLAQTLAKILDVPFTMADATSLTEAGYVGEDVENILLRLLIASEFNIAKAQKGIIYIDEVDKIARKSENPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQDFVQLDTSNILFICGGAFMGIDSIITSRTNHSSIGFAANVNIDKEKNNSEILKSLEIEDLTKFGLIPEFIGRLPIVTTLDELDKEALITILTKPKNAIVKQYQKQFELDDAELVIDYSALETIAEKALAKKTGARGLRSILEHLLLDSMYKVAELKKQRVTITKEVVNGLVEPIMTSLISTKSNKKQPIITDIPA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: RL16_ANAMM
Sequence: MLFVPKKTKYSKSFKGRIKGQTKGGSELAFGSCGLKALEPCRLTSKQIESARRSISRSLRRVGKVWIRVFCHLPVSKKPVDVRMGKGKGSIEMWVCRVQPGRVLFEIGGVSSVLAREALRKASAKLPMRCSYIEDGLR
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.