PharMolix/UniProtQA huggingface dataset:
Protein: TEFM_DANRE
Sequence: MWIVKGILSSVVLKGHYSLFSRPPPSSLPDYALRFLHFTCCRSSKIMFSEFDSSNASISPELRQENAKALDSCYTEEQRAVILQRLNTATESELEQVKLLRGRKSVNIVKYRTRHGPFSSLESVINVPLLKYKSAIMVFDSILNPDNKRKRNKGKVHLAKFIKPDVNRAHLEDASSIISIVCGTNKIAWAHMDRARTVLDWQQAECQSFMKGTYLASDYLEDISSVISSFPAADFFLVEKPSISPQNTSLFPVMVHLRTVEAMLFALLSQAREPGSPPKVLNMMRISVGRHFDLMVGDCRTSGAETLRKMMTDSVMKRDPRVLFPHDLVLKHRNSFQMSSRNKGEEMCDALLQAVAFFELLQE
What is the function of this protein?
Transcription elongation factor which increases mitochondrial RNA polymerase processivity.  Regulates transcription of the mitochondrial genome, including genes important for the oxidative phosphorylation machinery (By similarity).
What are the official names of this protein?
Transcription elongation factor, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the TEFM family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Mitochondrion matrix, mitochondrion nucleoid.
Protein: AGP12_ARATH
Sequence: MESMKMKLIVVLMVAIVAFSAVGNVAAQTEAPAPSPTSDAAMFVPALFASVAALASGFLF
What is the function of this protein?
Proteoglycan that seems to be implicated in diverse developmental roles such as differentiation, cell-cell recognition, embryogenesis and programmed cell death.
What are the official names of this protein?
Arabinogalactan protein 12, AtAGP12, Arabinogalactan peptide 12, AG-peptide 12.
What is the protein family that this protein belongs to?
Belongs to the AG-peptide AGP family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: NUDL_YERPN
Sequence: MSELITGQYLSEFINRFQLQLPQPDNVLTHSHYFSATNRRAAVLIPIICRPEPTLLLTRRADHLRKHAGQVAFPGGKADPDDQSLISTALREAEEEVAIPASVVHVLGKLAPLNSSSGYHVTPIVGLVPANIPFYGNDEEVAGLFEIPLHEALSLSRYHSLDIHREGINHRVYLSWYENQFIWGLTATIIRHLAQQVSI
What is the function of this protein?
Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.
What are the official names of this protein?
Uncharacterized Nudix hydrolase NudL.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. PCD1 subfamily.
Protein: RS3_GEOMG
Sequence: MGQKVNPIGFRLGVIRTWDSRWYAEADYAKLLHEDIKLRNFLKKRLFNSGVSKIEIERAASKAKINIFTARPGLIIGKKGAEVETLKKELAKLTDKEIYLNIQEVRKPELDAQLVSENVALQLERRVAFRRAMKKSVTSALKFGAKGIRITCSGRLGGAEMSRTEWYREGRVPLHTLRADIDYGFAEAKTTYGIIGVKVLIFKGEVLPGQK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RL7_LIMRJ
Sequence: MAFDKDAIIASLKEASISDLNDLVKAIEEEFDVSAAAPVAVAGAAGGDAAAKDSFTVELTEPGSAKVKVIKAVKDITGLGLKDAKDLVDGAPSAIKEDVKEDEANDIKEKLEAAGATVTLK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: TRMD_BURCJ
Sequence: MNQVTESAVQFDVITLFPEMFRALTDWGITSRAVKQGRFGLRTWNPRDFTTDNYRTVDDRPYGGGPGMVMLARPLEAAIDAAKAAQAEQGIASTRVVMMSPQGAPLTHDRAVRMAQEPGVVVLCGRYEAIDQRLLDRCVDEEISLGDFVLSGGELPAMAMMDAVVRLLPGVLNDSLSAVQDSFADGLLDCPHYTRPEEYDGVRVPDVLLGGHHAEIEKWRRQEALRNTLRKRPDLIVRARREKLLSRADEAWLANLAREAKDAS
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y134_MYCPN
Sequence: MEKIQAEKSQSAIEFKNIVVDFGESIAIDNINLTVKKKELVTLLGPSGCGKTTSLSVIAGLIAPTSGQVLFNGYDVTKKPPQQRKLGLVFQNYALYPHMSVFENIVFPLYSDTSWREAIFEKNTWAQHDINCLILKANGATSEELAELNRLMQQRIDEPKRMAYQINDLMVSVFQKQSELEANLKLIPRKKQFAIISLSKETLSQIRDVETKAKAALETADSAEVEQTIKSELKQKLSEIKANYHDEKANIKAYWWEMLANIKTELKTEKTAIKQTNDYAKLKELKWKIHFEPLNLKKQYRSYFKQLKAKYSLKDGNLTESELSQIEELQKRIVSLKDFINRTAKEVAEKLEITKILHKRPANISGGQQQRVAIARAIVRRPKVLLMDEPLSNLDAKLRVQTRQWIRKFQQDLQITTVFVTHDQEEAMSISDTIVCMSTGKVQQIGSPSELYLKPANEFVATFLGSPEMNIVNATVKAGQLLWNENPLVKTKFDLPDGAIRVGFRYDEVTAPKNDGSPVFSGTLISVENLGKHMVGVVESNGVQLNVRLELSHQFEVGNAVKFTIKPNGLHFFDPQTTQRVEVKHV
What are the official names of this protein?
Putative ABC transporter ATP-binding protein MG187 homolog.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: PCHF_PSEAE
Sequence: MSLGELLETCRSRRIELWSEAGRLRYRAPQGALDAGLAERLRAEREALLEHLEGGPGWRAEPDMAHQRFPLTPVQAAYVLGRQAAFDYGGNACQLYAEYDWPADTDPARLEAAWNAMVERHPMLRAVIEDNAWQRVLPEVPWQRLTVHACAGLDEAAFQAHLERVRERLDHACAALDQWPVLRPELSIGRDACVLHCSVDFTLVDYASLQLLLGEWRRRYLDPQWTAEPLEATFRDYVGVEQRRRQSPAWQRDRDWWLARLDALPGRPDLPLRVQPDTRSTRFRHFHARLDEAAWQALGARAGEHGLSAAGVALAAFAETIGRWSQAPAFCLNLTVLNRPPLHPQLAQVLGDFTALSLLAVDSRHGDSFVERARRIGEQMFDDLDHPTFSGVDLLRELARRRGRGADLMPVVFTSGIGSVQRLLGDGEAPRAPRYMISQTPQVWLDCQVTDQFGGLEIGWDVRLGLFPEGQAEAMFDDFVGLLRRLAQSPRAWTDGDATEPVEAPPQALPGSARSIAAGFAERALLTPDATAIHDAAGSYSYRQVAQHASALRRVLEAHGAGRGRRVAVMLPKSAAQLVAVIGILQAGAAYVPVDIRQPPLRRQAILASAEVVALVCLESDVPDVGCACVAIDRLAADSAWPPPPAAEVAADDLAYVIYTSGSTGTPKGVMLSHAAVSNTLLDINQRYGVDANDRVLGLAELSFDLSVYDFFGATAAGAQVVLPDPARGSDPSHWAELLERHAITLWNSVPAQGQMLIDYLESEPQRHLPGPRCVLWSGDWIPVSLPTRWWRRWPDSALFSLGGATEAAIWSIEQPIRPQHTELASIPYGRALRGQSVEVLDARGRRCPPGVRGEIHIGGVGLALGYAGDPQRTAERFVRHPDGRRLYRTGDLGRYLADGSIEFLGREDDQVKIRGHRIELAELDAALCAHPQVNLAATVVLGETHERSLASFVTLHAPVEAGEDPRTALDAVRQRAAQALRRDWGSEEGIAAAVAALDRACLASLAAWLAGSGLFASATPLDLATLCQRLGIAEARQRLLRHWLRQLEEGGYLRAEGEGWLGCAERPAQSPEDAWTAFAGCAPAALWPAELVAYLRDSAQSLGEQLAGRISPAALMFPQGSARIAEAMYSQGLHAQALHEAMAEAIAAIVERQPQRRWRLLELGAGTAAASRTVIARLAPLVQRGAEVDYLFTDVSSYFLAAARERFADQPWVRFGRFDMNGDLLDQGVAPHSVDILLSSGALNNALDTPALLAGLRELLSADAWLVIQELTREHNEISVSQSLMMENPRDLRDERRQLFVHTGQWLEWLAAQGGDLACGVVPPGSALDLLGYDVLLARCKTDRARLEPAELLAFVEARVPRYMLPAQLRVLERLPVTGNGKIDRKALTGFARQPQADLRHGVAQAPADELENALLALWREVLDNPSLGVEQDFFGAGGDSLLIAQLIARLRERLESARRHPFDRLLRWALSQPTPRGLAERLRSAPEEGRGPALAAARGVAPAPAGMSRAPLAEGAVALDPLVRLVPGEGVPRVLVHEGLGTLLPYRPLLRALGEGRPLLGLAVHDSDAYLAIPAEHLNACLGRRYAEALHRAGLREVDLLGYCSGGLVALETAKSLVQRGVRVRQLDIVSSYRIPYRVDDERLLLFSFAATLGLDTAALGFPAPERLGQAVQAALAQTPERLVAEALAGLPGLADLVALRGRVLQAASGSADAVSVERDTLYRLFCHSVRASQAEAPEPYVGALRLFVPDAGNPLVPRYAEALETQWRAAALGACGIHEVPGGHFDCLGEALAQSLSKPMPEEASR
What is the function of this protein?
Involved in the biosynthesis of the siderophore pyochelin (PubMed:9846750, PubMed:11208777).  Adenylates L-cysteine and loads it onto its peptidyl carrier domain via a thioester linkage to the phosphopanthetheine moiety (By similarity).  Then forms a peptide bond between the salicyl-thiazolinyl intermediate bound to the second carrier domain of PchE and the cysteine bound to its own peptidyl carrier domain to form the salicyl-thiazolinyl-cysteinyl-S-PCP2 intermediate.  It subsequently cyclizes the C-terminal cysteine to form the second thiazoline heterocycle in the salicyl-thiazolinyl-thiazolinyl-S-PCP2 intermediate (By similarity).  When this intermediate is released by the action of a thioesterase, it produces the tricyclic acid hydroxyphenyl-thiazolyl-thiazolinyl-carboxylic acid (HPTT-COOH), an advanced intermediate containing the aryl-4,2-bis-heterocyclic skeleton of the bithiazoline class of siderophores (By similarity).
What are the official names of this protein?
Pyochelin synthase PchF, L-cysteine--[L-cysteinyl-carrier protein] ligase, Nonribosomal peptide synthase PchF.
What is the protein family that this protein belongs to?
Belongs to the NRP synthetase family.
Protein: PSBA_OENAR
Sequence: MTAILERRESESLWGRFCNWITSTENRLYIGWFGVLMIPTLLTATSVFIIAFIAAPPVDIDGIREPVSGSLLYGNNIISGAIIPTSAAIGLHFYPIWEAASVDEWLYNGGPYELIVLHFLLGVACYMGREWELSFRLGMRPWIAVAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANEGYRFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGIWFTALGISTMAFNLNGFNFNQSVVDSQGRVINTWADIINRANLGMEVMHERNAHNFPLDLAAVEAPSTNG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: NCAP_IBVH1
Sequence: MASGKTTGKTDAPAPVIKLGGPKPPKVGSSGNASWFQALKAKKLNSPPPKFEGSGVPDNENLKLSQQHGYWRRQARYKPGKGGKKSVPDAWYFYYTGTGPAADLNWGDSQDGIVWVSAKGADTKSRSNQGTRDPDKFDQYPLRFSDGGPDGNFRWDFIPINRGRSGRSTAASSAASSRAPSRDGSRGRRSGAEDDLIARAAKIIQDQQKKGSRITKAKADEMAHRRYCKRTIPPGYKVDQVFGPRTKGKEGNFGDDKMNEEGIKDGRVIAMLNLVPSSHACLFGSRVTPKLQPDGLHLRFEFTTVVSRDDPQFDNYVKICDQCVDGVGTRPKDDEPRPKSRPNSRPATRTSSPAPRQQRQKKEKKSKKQDDEVDKALTSDEERNNAQLEFDDEPKVINWGDSALGENEL
What is the function of this protein?
Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M.  Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, NC, Protein N.
What is the protein family that this protein belongs to?
Belongs to the gammacoronavirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum-Golgi intermediate compartment. Host Golgi apparatus. Note=Located inside the virion, complexed with the viral RNA. Probably associates with ER-derived membranes where it participates in viral RNA synthesis and virus budding.
Protein: TRMHL_STAAM
Sequence: MEDTVIVGRHAVREAIITGHPINKILIQEGIKKQQINEILKNAKDQKIIVQTVPKSKLDFLANAPHQGVAALIAPYEYADFDQFLKQQKEKEGLSTVLILDGLEDPHNLGSILRTADATGVDGVIIPKRRSVTLTQTVAKASTGAIEHVPVIRVTNLAKTIDELKDNGFWVAGTEANNATDYRNLEADMSLAIVIGSEGQGMSRLVSDKCDFYIKIPMVGHVNSLNASVAASLMMYEVFRKRHDVGEI
What are the official names of this protein?
Putative TrmH family tRNA/rRNA methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
Protein: LUXS_CHRSD
Sequence: MSDKEMNVESFNLDHTKVKAPYVRLAGIKTGDHGDAIHKYDLRICQPNKAHMEMPALHSLEHLMAELSRNHTDKMLDISPMGCQTGFYVTLINHDDYDDVLDLIDKTLNDVLVAKEVPACNEMQCGWAASHSLEGAQALARDLLAKRNEWNQVFA
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: Y1408_ARCFU
Sequence: MLPGLAMSLSMDSFSVWMRKNLKSAYEGLVTQDIDFVFLSKKKKVFFFVEEKNSLNAKLRLPQRVIFMLFNEFLINDLSEWKFLGTDVLYVLEDGTVYFLNDKNEKVRVNIEDYIVYKLENYKIFKDFQIEEYMLKMLWDCRKN
What are the official names of this protein?
Uncharacterized protein AF_1408.
Protein: CDK1B_XENLA
Sequence: MDEYTKIEKIGEGTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQHPNIVCLLDVLMQDSRLYLIFEFLSMDLKKYLDSIPSGQYIDTMLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDNKGVIKLADFGLARAFGIPVRVYTHEVVTLWYRASEVLLGSVRYSTPVDVWSVGTIFAEIATKKPLFHGDSEIDQLFRIFRSLGTPNNEVWPEVESLQDYKNTFPKWKGGSLSSNVKNIDEDGLDLLSKMLVYDPAKRISARKAMLHPYFDDLDKSSLPANQIRN
What is the function of this protein?
Plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and regulates G1 progress and G1-S transition via association with multiple interphase cyclins.  Required in higher cells for entry into S-phase and mitosis.  May play a role in regulating the amplitude of the cyclic expression of circadian clock genes.
What are the official names of this protein?
Cyclin-dependent kinase 1-B, CDK1-B, Cell division control protein 2 homolog 2, Cell division control protein 2-B, Cell division protein kinase 1, p34 protein kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: DSP2_ARATH
Sequence: MKLIEKTMSMNQFRTMEEEKQDGGELFHTIEVAKVDRNNVSQPPPAATAALLEVPGDELNLIPPLNFSMVDNGIFRSGFPDSANFSFIKTLGLRSIISLCPEPYPENNMQFLKSNGISLFQFGIEGSKSKCLPGLENEVWLHIWSSKHQKEDFYTNGNSKTSEPFVDILDQKIREALKVLLDEKNHPLLIHCKRGKHRTGCLVGCMRKLQKWCITSILDEYKRFAAAKARVSDQRFLESFDVSGLKHTPMSFSCSNR
What is the function of this protein?
Possesses phosphotyrosine phosphatase activity in vitro (PubMed:21409566).  Hydrolyzes para-nitrophenyl phosphate in vitro (PubMed:17976645, PubMed:21409566).  Hydrolyzes O-methylfluorescein phosphate in vitro.  Dephosphorylates the phosphoinositides PI(3,5)P2 (PubMed:21409566).
What are the official names of this protein?
Tyrosine-protein phosphatase DSP2, Protein PLANT AND FUNGI ATYPICAL DUAL-SPECIFICITY PHOSPHATASE 2, AtPFA-DSP2.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family.
Protein: TTC29_MACFA
Sequence: MTTLPPLPMTRPKLTALARQKLPCSSRKIPRSQLIKEKDDIDHYLEVNFKGLSKEEVAAYRNSYKKNICVDMLRDGYHKSFTELFALMEQWDALREAARVRSLFWLQKPLEEQPDKLDYFYHYLTRAEDAERKKSFEDVYNNLYALACYFNNPEDKWVRNHFYERCFKIAQLIKIDGGKKEAEAHMHMGLLYEEDGQLLEAAEHYEAFHQLTQGRIWKDETGRSLNLLACESLLRTYRLLSDKMLQNKEYKQAIKILIKASEIAKEGSDKKMEGEASYYLGLAHLAAEEYETALTVLDTYCKISTELDDDLSLGRAYEAIAKVLQSQGNTTEAIKYLKKFVKIARNNFQSLDFVRASTMLGDIYNEKGHYNKASQRFQQAFDTTVELMSMPLMDETKVHYGIAKAHQMMLTVNNYIESADLTSLNYLLSWKESRGDIEPDPVTEEFRGSTVETVSQNSEHLEELSRFPGDQKNET
What is the function of this protein?
Axonemal protein which is implicated in axonemal and/or peri-axonemal structures assembly and regulates flagella assembly and beating and therefore sperm motility.
What are the official names of this protein?
Tetratricopeptide repeat protein 29, TPR repeat protein 29.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, flagellum axoneme.
Protein: SLA1_TRIAB
Sequence: DCPSDWSSYDQYCYRVFKRIQTWEDAERFCSEQANDGHLVSIESAGEADFVTQLVSENIRSEKHYVWIGLRVQGKGQQCSSEWSDGSSVHYDNLQENKTRKCYGLEKRAEFRTWSNVYCGHEYPFVCKFXR
What is the function of this protein?
Potent platelet activator that aggregates platelets via both GPIbalpha (GP1BA) and GPVI (GP6).  Induces a tyrosine phosphorylation profile in platelets that resembles this produced by collagen, involving the time dependent tyrosine phosphorylation of Fc receptor gamma chain (FCGR1A), phospholipase Cgamma2 (PLCG2), and LAT.
What are the official names of this protein?
Snaclec alboaggregin-A subunit alpha, 50-kDa alboaggregin, Alboaggregin-A subunit 1, AL-A subunit 1.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: TCPQ_BOVIN
Sequence: MALHVPKAPGFAQMLKEGAKHFSGLEEAVYRNIQACKELAQTTRTAYGPNGMNKMVINHLEKLFVTNDAATILRELEVQHPAAKMIVMASHMQEQEVGDGTNFVLVFAGALLELAEELLRLGLSVSEVIEGYEIACKKAHEILPDLVCCSAKNLRDVDEVSSLLHTSVMSKQYGNEVFLAKLIAQACVSIFPDSGHFNVDNIRVCKILGSGVHSSSVLHGMVFKKETEGDVTSVKDAKIAVYSCPFDGMITETKGTVLIKSAEELMNFSKGEENLMDAQVKAIADTGANVVVTGGRVADMALHYANKYNIMLVRLNSKWDLRRLCKTVGATALPRLNPPVLEEMGHCDSVYLSEVGDTQVVVFKHEKEDGAISTIVLRGSTDNLMDDIERAVDDGVNTFKVLTRDKRLVPGGGATEIELAKQITSYGETCPGLEQYAIKKFAEAFEAIPRALAENSGVKANEVISKLYAVHQEGNKNVGLDIEAEVPAVKDMLEAGVLDTYLGKYWAIKLATNAAVTVLRVDQIIMAKPAGGPKPPSGKKDWDEDQND
What is the function of this protein?
Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis.  The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance.  As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia.  The TRiC complex plays a role in the folding of actin and tubulin.
What are the official names of this protein?
T-complex protein 1 subunit theta, TCP-1-theta, CCT-theta.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium basal body.
Protein: SYFA_SINMW
Sequence: MSELETLERTLLAEIEAAADEGAIEAVRVGALGKKGSISELLKTLGSMSAEERQTRGARINALKNTVSEAISARKAELKDAAIAERLARETVDISLPVRSSPAERGRIHPISQIVDEITAIFGDMGFSLAEGPDIETDYYNFTALNFPEGHPAREMHDTFFFAPDEKGERKVLRTHTSPVQIRTMEAEQPPIRIIIPGKTYRQDSDATHSPMFHQVEGLVIDRTANVANMRWVLEEFCKAFFEVDQVTMRFRPSFFPFTEPSFEVDIQCDRSGPIVKFGEGKDWMEILGCGMVHPNVLRAGGLDPDEFQGFAWGMGLDRIAMLKYGMPDLRDFFNADVRWMTHYGFRPLDMPTLFGGLSA
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOVE_ASPTE
Sequence: MAADQGIFTNSVTLSPVEGSRTGGTLPRRAFRRSCDRCHAQKIKCTGNKEVTGRAPCQRCQQAGLRCVYSERCPKRKLRQSRAADLVSADPDPCLHMSSPPVPSQSLPLDVSESHSSNTSRQFLDPPDSYDWSWTSIGTDEAIDTDCWGLSQCDGGFSCQLEPTLPDLPSPFESTVEKAPLPPVSSDIARAASAQRELFDDLSAVSQELEEILLAVTVEWPKQEIWTRASPHSPTASRERIAQRRQNVWANWLTDLHMFSLDPIGMFFNASRRLLTVLRQQAQADCHQGTLDECLRTKNLFTAVHCYILNVRILTAISELLLSQIRRTQNSHMSPLEGSRSQSPSRDDTSSSSGHSSVDTIPFFSENLPIGELFSYVDPLTHALFSACTTLHVGVQLLRENEITLGVHSAQGIAASISMSGEPGEDIARTGATNSARCEEQPTTPAARVLFMFLSDEGAFQEAKSAGSRGRTIAALRRCYEDIFSLARKHKHGMLRDLNNIPP
What is the function of this protein?
Transcription factor that regulates the expression of the he gene cluster that mediates the biosynthesis of lovastatin (also known as mevinolin, mevacor or monacolin K), a hypolipidemic inhibitor of (3S)-hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR).
What are the official names of this protein?
Transcriptional regulator LovE, Lovastatin biosynthesis cluster protein E.
What are the subcellular locations of this protein?
Nucleus.
Protein: CEP1_CAEBR
Sequence: MNTEATDSQLSVLIKKEKIVPDSQEVDGNTTRELGDNTLDEIINGQFSPLMSQNSENELEKHLRSTPGIEGVFESLLHNEIQEPDITHLSLMSTHPSESGRQPELIKTRTRTPRIVNDGPLQQTSRSELLDLNALFDTEESALMNQSIESETTLTQFLGGSQPIDYLRERTKEEQDKRNQMRQEEKLIKKMQKAQVEKARSEMFSERNHEFEPMECDNDEEDVFRAVKEDSSNREKEEEWLTFEVKKERASKVSDFEFETVVNDGIYLWAKMKCNIPFIVKWNVSSCHKQLFLKVRLVNYMASDNIENSIRVPSNLAKCHNHRMTEEKTPRESFFYVVKSGEHWTPQINSKKDQCFVAKLAPGTTQVLFDLIFKCQRSCLDLAERRKRMCLAVFLEDENGNELLHDVIKQLLIVGYPRRDWKNFCEKRGDFKFSEKSLLVQTTNNIFADQSSLHSGPSSPEKVTDTSQMFQSTSSSSRKRAASDVKFVASAVPSSDQQSYPMRLHGCESRRMEMSFYRKFKENEDSLSNKRPRSQYGLQRQVKLSEKEYSKFVAFFAKEGENEISKYASAHCLTPAQASRLDPSDKIEKFLAFVGDESAADNFRKHGLFTMLDLDKYFQVYDSAFETIGVDSSKMEKYYDLFLHYHRVQENIRYNQPK
What is the function of this protein?
Transcriptional activator that binds the same DNA consensus sequence as p53.  Has a role in normal development to ensure proper meiotic chromosome segregation.  Promotes apoptosis under conditions of cellular and genotoxic stress in response to DNA damage, hypoxia, or starvation.  However, not required for DNA repair in response to UV-C or to regulate cell-cycle progression.  Regulates germline apoptosis in response to DNA damage.  Required for induction of ced-13 in response to DNA damage.  Its pro-apoptotic activity is inhibited when bound to ape-1 in vitro (By similarity).  Regulates germline proliferation by activating phg-1.  Regulates DNA damage-induced apoptosis by inducing transcription of the programmed cell death activator egl-1.  Negatively regulates lifespan.
What are the official names of this protein?
Transcription factor cep-1.
What is the protein family that this protein belongs to?
Belongs to the p53 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TDC2_CAMAC
Sequence: MGSIDSNYDTESAGQCRPLEPEEFRKQAHQMVDFIADYYKNIESYPVLSQVEPGYLQSRLPETAPYRPEPFESILKDVHKDIIPGVTHWLSPNFFAYFPATVSSAAFVGEMLCTCFNAVGFNWLASPAELELEMVVMDWLASMLKLPNSFTFLGTGGGVIQGTTSEAILCTLIAARDRALESIGVDSIHKLVVYGSDQTHSTYAKACNLAGILPCNIRSIRTEAVANFSLSPDSLHREIEADVAAGMVPLYLCATVGTTSTTAIDSLSPLADVANDYGLWFHVDAAYAGSACICPEFRHYLDGIERADSLSLSPHKWLLSYLDCCCLWVKRPSVLVKALSTDPEYLKNKPSESNSVVDFKDWQVGTGRRFKALRLWFVMRSYGVANLQSHIRSDIQMAKMFEEFVNSDPRFEIVVPRVFSLVCFRLNPFSKSDPCNTELLNRKLLEWVNSTGQVYITHTKVGGVYMLRFAVGATLTEEHHVSAAWKLIREGADALLCS
What is the function of this protein?
Involved in the biosynthesis of tryptamine.  Supplies tryptamine for the indole moiety of camptothecin (CPT), an anti-cancer monoterpene alkaloid.  Represents a key step in monoterpene indole alkaloid biosynthesis.  Is specific for tryptophan, and inactive against tyrosine, phenylalanine and 3,4-dihydroxyphenylalanine (dopa).
What are the official names of this protein?
Tryptophan decarboxylase TDC2.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
Protein: TGFB2_MOUSE
Sequence: MHYCVLSTFLLLHLVPVALSLSTCSTLDMDQFMRKRIEAIRGQILSKLKLTSPPEDYPEPDEVPPEVISIYNSTRDLLQEKASRRAAACERERSDEEYYAKEVYKIDMPSHLPSENAIPPTFYRPYFRIVRFDVSTMEKNASNLVKAEFRVFRLQNPKARVAEQRIELYQILKSKDLTSPTQRYIDSKVVKTRAEGEWLSFDVTDAVQEWLHHKDRNLGFKISLHCPCCTFVPSNNYIIPNKSEELEARFAGIDGTSTYASGDQKTIKSTRKKTSGKTPHLLLMLLPSYRLESQQSSRRKKRALDAAYCFRNVQDNCCLRPLYIDFKRDLGWKWIHEPKGYNANFCAGACPYLWSSDTQHTKVLSLYNTINPEASASPCCVSQDLEPLTILYYIGNTPKIEQLSNMIVKSCKCS
What is the function of this protein?
Multifunctional protein that regulates various processes such as angiogenesis and heart development (By similarity).  Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains remain non-covalently linked rendering TGF-beta-2 inactive during storage in extracellular matrix (By similarity).  At the same time, LAP chain interacts with 'milieu molecules', such as LTBP1 and LRRC32/GARP, that control activation of TGF-beta-2 and maintain it in a latent state during storage in extracellular milieus (By similarity).  Once activated following release of LAP, TGF-beta-2 acts by binding to TGF-beta receptors (TGFBR1 and TGFBR2), which transduce signal (By similarity).
What are the official names of this protein?
Transforming growth factor beta-2 proprotein.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
[Latency-associated peptide]: Secreted, extracellular space, extracellular matrix. SUBCELLULAR LOCATION: [Transforming growth factor beta-2]: Secreted.
Protein: HISZ_DESRM
Sequence: MTSSRFGRLAPGVRDVLPAEAHLMRGLKEKFTKLVETWGYKEVVTPTFEYMENLASEELQEEKFFKFLDRQGHLMALRPDMTRPMARLVATRMKGITPPLRLFYLANVFNYEQPQVGRQREFYQAGVELMGPSSPEADAEVVAMVAEYLMQTGLADFQISIGNVGIFHGLVKQLGLPKEVAQELKEALGNKDFVKVEEILGSHAATPEEARRTLDLIELRGGPEILDRAFGLAQPGPAADAIDNLRQLYWGLTCYGVERHITLDLGLLRGLDYYTGLVFEGYTVAMGFPICGGGRYNQLLAKFGLPMPATGFAVNLERVLVALERLQGPPREPVPDVLVAWEDNSLANALQCVKELRYQGLKVVTAMFEYPPAKAKAEARSLGASRVIYFDKEGKSEELSL
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.