PharMolix/UniProtQA huggingface dataset:
Protein: IL12A_SHEEP
Sequence: MCPLRSLLLISTLVLLHHLPHLSLGRSLPTTTAGPGTSCLDYSQNLLRAVSNTLQKARQTLEFYSCTSEEIDHEDITKDKTSTVEACLPLELATNESCLASRETSLITNGHCLSSGKTSFMTTLCLRSIYKDLKMYHMEFQAMNAKLLMDPKRQVFLDQNMLAAIAELMQALNFDSETVPQKPSLEELDFYKTKVKLCILLHAFRIRAVTIDRMMSYLSSS
What is the function of this protein?
Heterodimerizes with IL12B to form the IL-12 cytokine or with EBI3/IL27B to form the IL-35 cytokine.  IL-12 is primarily produced by professional antigen-presenting cells (APCs) such as B-cells and dendritic cells (DCs) as well as macrophages and granulocytes and regulates T-cell and natural killer-cell responses, induces the production of interferon-gamma (IFN-gamma), favors the differentiation of T-helper 1 (Th1) cells and is an important link between innate resistance and adaptive immunity.  Mechanistically, exerts its biological effects through a receptor composed of IL12R1 and IL12R2 subunits.  Binding to the receptor results in the rapid tyrosine phosphorylation of a number of cellular substrates including the JAK family kinases TYK2 and JAK2.  In turn, recruited STAT4 gets phosphorylated and translocates to the nucleus where it regulates cytokine/growth factor responsive genes (By similarity).  As part of IL-35, plays essential roles in maintaining the immune homeostasis of the liver microenvironment and functions also as an immune-suppressive cytokine (By similarity).  Mediates biological events through unconventional receptors composed of IL12RB2 and gp130/IL6ST heterodimers or homodimers.  Signaling requires the transcription factors STAT1 and STAT4, which form a unique heterodimer that binds to distinct DNA sites (By similarity).
What are the official names of this protein?
Interleukin-12 subunit alpha, IL-12A, Cytotoxic lymphocyte maturation factor 35 kDa subunit, CLMF p35, IL-12 subunit p35.
What is the protein family that this protein belongs to?
Belongs to the IL-6 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GLGA_FUSNN
Sequence: MKVLFATGEAFPFVKTGGLGDVSYSLPKTLKQKENVDIRVILPKYSKISNELLKDARHLGHKEIWVAHHNEYVGIEEVELEGVIYYFVDNERYFKRPNVYGEFDDCERFLFFCKAVVETMDITKFKPDIIHCNDWQSALIPIYLKERGIYDVKTIFTIHNLRFQGFFFNNVIEDLLEIDRAKYFQEDGLKYYDMISFLKGGVVYSDYITTVSDSYAEEIKTQELGEGIHGLFQKYDYKLSGIVNGIDKISYPLSKKPHKILKADLQKKLGLDVEEDTPLIVIITRLDRQKGLDYIVEKFDEMMSLGIQFILLGTGEKRYEHFFAYQEYLHKGQVCSYIGFNQELSTEIYAGADIFLMPSVFEPCGLSQMIAMRYGCIPVVRETGGLKDTVKPYNEYTGEGDGFGFKQANADDMIKTLKYAIKMYHRPNVWQEIIKNAKKRDNSWDKPAKRYKELYQRLIEG
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: GLPK_STRPQ
Sequence: MSQEKYIMAIDQGTTSSRAIIFNQKGEKVSSSQKEFPQIFPHAGWVEHNANQIWNSVQSVIAGAFIESSIKPSQIEAIGITNQRETTVIWDKKTGVPIYNAIVWQSRQTAPIAEQLKQDGHTKMIHEKTGLVIDAYFSATKIRWILDHVPGAQERAEKGELLFGTIDTWLVWKLTDGAVHVTDYSNAARTMLYNIKDLTWDDEILELLNIPKDMLPEVKSNSEIYGKTAAFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNTGDEMQLSSNNLLTTIGYGINGKVHYALEGSIFIAGSAIQWLRDGLKMIETSPESEQFALASTSDDEVYVVPAFTGLGAPYWDSNARGSVFGLTRGTSKEDFVKATLQSIAYQVRDVIDTMQVDSGIDIQQLRVDGGAAMNNMLMQFQADILGIDIARAKNLETTALGAAFLAGLAVGYWEDMDALKELNATGQLFKASMNESRKEKLYKGWKRAVKATQVFTQEEDADDDAK
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: SELW_MOUSE
Sequence: MALAVRVVYCGAUGYKPKYLQLKEKLEHEFPGCLDICGEGTPQVTGFFEVTVAGKLVHSKKRGDGYVDTESKFRKLVTAIKAALAQCQ
What is the function of this protein?
Plays a role as a glutathione (GSH)-dependent antioxidant.  May be involved in a redox-related process.  May play a role in the myopathies of selenium deficiency.
What are the official names of this protein?
Selenoprotein W, SelW.
What is the protein family that this protein belongs to?
Belongs to the SelWTH family. Selenoprotein W subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA2B2_TRIST
Sequence: SLLQLRKMIKKMTNKEPILSYSKYGCNCGMAGRGKPVDATDXCCXXHDCCYGKVTSCSTKADSYSYSWEE
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that exhibits strong myotoxicity.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Basic phospholipase A2 2, svPLA2, PLA2-II, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PXG_SESIN
Sequence: MATHVLAAAAERNAALAPDAPLAPVTMERPVRTDLETSIPKPYMARGLVAPDMDHPNGTPGHVHDNLSVLQQHCAFFDQDDNGIIYPWETYSGLRQIGFNVIASLIMAIVINVALSYPTLPGWIPSPFFPIYLYNIHKAKHGSDSGTYDTEGRYLPMNFENLFSKHARTMPDRLTLGELWSMTEANREAFDIFGWIASKMEWTLLYILARDQDGFLSKEAIRRCYDGSLFEYCAKMQRGAEDKMK
What is the function of this protein?
Calcium-binding peroxygenase involved in the degradation of storage lipid in oil bodies.  May be involved in the interaction between oil bodies and vacuoles during seed germination (By similarity).
What are the official names of this protein?
Peroxygenase, Caleosin, SiCLO.
What is the protein family that this protein belongs to?
Belongs to the caleosin family.
What are the subcellular locations of this protein?
Lipid droplet. Microsome membrane.
Protein: UPPP_CLOTE
Sequence: MLLILKAIILAIVEGLTEFVPVSSTGHLILVSDVINFKGDYANLFNVVIQLGAILAVVVVYWDKLLNSVKDIFAPDRRGLRFWINIVVACIPAVIFGFSLDDYIDKYLFNPITVAIGLVIGGILMIIVENKYRRRSKTKNIYDMKLRQSIFVGMFQCLALWPGMSRSASTIMGGWIAGLSPVVAAEFSFFLAIPVMVGASGLKLVKSGFYMTNIEFIALIVGFVGAFLVSLVVIEKFIKFLQKKPMRIFAIYRIFIGAILLILAIFKIVTI
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y3482_PSYIN
Sequence: MKFGRKIVMDKVKVTYQYLLFVWRRSEQDNIKVPAGHLAYVTLLSIVPLLAVIFYMLAAFPVFSDLKGMLEDLIYNNLLPTSGDTIQEHISGFIENTKKMSMMGIGSLIAIALLLISTIDQTINRIWRCTNKRSRIQSFTIYWTILSLGPVIIGASLALSSYLFSVFQEHGSLSFGQRLLSLMPFILTWLTFAGVYTLVPHQRVSFRYALIGGLIAAILFFFGTDLFRLYITNFPSQQIIYGALAVIPILFVWIYYSWLIVLIGAEVTATLEEFLKQQEDNNVTKEYLGADI
What are the official names of this protein?
UPF0761 membrane protein Ping_3482.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MRAY_PROM5
Sequence: MIHQKMIGKTRRLDFTTLFFLITLSLIVNSFIFNNLLIICIFLVFFSICILITNYGLKIIKQLNLLQNIRDTGPSFHFNKKNTPTMGGIFIILPLLLLLLIVNHYFYSMGIILLFFGSLSFFIIGFLDDYLSIKKKKNIGLRSTQKFILQSLISILFIVLAYQNGYINSLITVSNNWAIDTNIVIFPICFVTLVGLSNAVNLTDGLDGLASGCGSIVFYGLGTEIFIKGQQELIIYGLIAYAMSGLCVGFLKFNKYPAKIFMGDTGSLTIGATLGYISILTNSYFTLFIISGIFVIEALSVIIQVSFFKITKKIFKRGKRVFLMTPIHHHFELSGMKEEKIVENFWKINILLVILGIVLKINL
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ANDR_PAPHA
Sequence: MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLQQQQQQQQQETSPRQQQQQQGEDGSPQAHRRGPTGYLVLDEEQQPSQPQSAPECHPERGCVPEPGAAVAAGKGLPQQLPAPPDEDDSAAPSTLSLLGPTFPGLSSCSADLKDILSEASTMQLLQQQQQEAVSEGSSSGRAREASGAPTSSKDNYLGGTSTISDSAKELCKAVSVSMGLGVEALEHLSPGEQLRGDCMYAPVLGVPPAVRPTPCAPLAECKGSLLDDSAGKSTEDTAEYSPFKGGYTKGLEGESLGCSGSAAAGSSGTLELPSTLSLYKSGALDEAAAYQSRDYYNFPLALAGPPPPPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGELASLHGAGAAGPGSGSPSAAASSSWHTLFTAEEGQLYGPCGGGGGGGGGGGGGAGEAGAVAPYGYTRPPQGLAGQEGDFTAPDVWYPGGMVSRVPYPSPTCVKSEMGPWMDSYSGPYGDMRLETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETAQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ
What is the function of this protein?
Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.  Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation.  Transcription activation is also down-regulated by NR0B2.  Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.
What are the official names of this protein?
Androgen receptor, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Detected at the promoter of target genes. Predominantly cytoplasmic in unligated form but translocates to the nucleus upon ligand-binding. Can also translocate to the nucleus in unligated form in the presence of RACK1.
Protein: PDE4A_HUMAN
Sequence: MEPPTVPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYSDSAERAERERQPHRPIERADAMDTSDRPGLRTTRMSWPSSFHGTGTGSGGAGGGSSRRFEAENGPTPSPGRSPLDSQASPGLVLHAGAATSQRRESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSNKRSPLGGPTPVCKATLSEETCQQLARETLEELDWCLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPPPPVPHLQPMSQITGLKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAIRQSPSPPPEEESRGPGHPPLPDKFQFELTLEEEEEEEISMAQIPCTAQEALTAQGLSGVEEALDATIAWEASPAQESLEVMAQEASLEAELEAVYLTQQAQSTGSAPVAPDEFSSREEFVVAVSHSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACAGTFGEDTSALPAPGGGGSGGDPT
What is the function of this protein?
Efficiently hydrolyzes cAMP.
What are the official names of this protein?
cAMP-specific 3',5'-cyclic phosphodiesterase 4A, DPDE2, PDE46.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
What are the subcellular locations of this protein?
[Isoform 1]: Cytoplasm, perinuclear region. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm, perinuclear region. Cell projection, ruffle membrane. SUBCELLULAR LOCATION: [Isoform 3]: Cytoplasm, cytosol. SUBCELLULAR LOCATION: [Isoform 4]: Membrane; Peripheral membrane protein. Note=Isoform 4 has propensity for association with membranes. SUBCELLULAR LOCATION: [Isoform 6]: Cytoplasm, perinuclear region. SUBCELLULAR LOCATION: [Isoform 7]: Cytoplasm, cytosol. Membrane; Peripheral membrane protein. Note=Predominantly cytosolic.
Protein: GATA_COXBR
Sequence: MHQKTIAELKQDLRDKTISSVELTQHFLDRIKTINPTLNSFISITEEYALTQAKAADARLAKGEATSLTGIPIAQKDIFCTKDIKTSCGSKMLDNFIAPYDATVVEQLNKAGAILIGKTNMDEFAMGSSNENSYFGAVKNPWDLERVPGGSSGGSAAAVAARLVPGATGTDTGGSIRQPAALCGITGLKPTYGRVSRYGMIAFASSLDQAGPMAQTAEDAALLLNALAGHDAKDSTSINKNVPDYTATLTTSLEGLKVGLPKEYFGEGLNSSIAESIETVKKTLEKMGATFIEIQLPHTDFAAPAYYVLAPAECSSNLARYDGVRYGYRCDKPVDLDDLYKRSRTEGFGSEVKRRIMIGTYVLSAGYYDAYYLKAQKIRRLIRDDFMKAFETVDVILTPATPTPAFKLNEKIADPVAMYLSDVYTIAVNLAGLPAIAFPAGFMDQLPIGAQLIGNYFEEARLLNITHRYQQETDWHKQSPKLR
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: PP308_ARATH
Sequence: MLIPHYLHQLQLCARNRTLTTAKALHAHIVKLGIVQCCPLANTLVNVYGKCGAASHALQVFDEMPHRDHIAWASVLTALNQANLSGKTLSVFSSVGSSSGLRPDDFVFSALVKACANLGSIDHGRQVHCHFIVSEYANDEVVKSSLVDMYAKCGLLNSAKAVFDSIRVKNTISWTAMVSGYAKSGRKEEALELFRILPVKNLYSWTALISGFVQSGKGLEAFSVFTEMRRERVDILDPLVLSSIVGACANLAASIAGRQVHGLVIALGFDSCVFISNALIDMYAKCSDVIAAKDIFSRMRHRDVVSWTSLIVGMAQHGQAEKALALYDDMVSHGVKPNEVTFVGLIYACSHVGFVEKGRELFQSMTKDYGIRPSLQHYTCLLDLLGRSGLLDEAENLIHTMPFPPDEPTWAALLSACKRQGRGQMGIRIADHLVSSFKLKDPSTYILLSNIYASASLWGKVSEARRKLGEMEVRKDPGHSSVEVRKETEVFYAGETSHPLKEDIFRLLKKLEEEMRIRNGYVPDTSWILHDMDEQEKEKLLFWHSERSAVAYGLLKAVPGTPIRIVKNLRVCGDCHVVLKHISEITEREIIVRDATRYHHFKGGKCSCNDFW
What is the function of this protein?
Involved in C-to-U editing of mitochondrial RNA.  Required specifically for editing the mitochondrial NAD4, MT-CYB/COB and RPL16 transcripts.
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At4g14050, mitochondrial, Mitochondrial editing factor 35.
What is the protein family that this protein belongs to?
Belongs to the PPR family. PCMP-H subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: Y612_RICPR
Sequence: MQKILIEGYDISKDNANPDIKEIRNLDHLPSAKACEYFIHAHGAEFFYQNSHLGLLGKIQSYFMPDPSYLSLTMSSNGGATPMLDITLLNKIQRNTPANQCNIVHIFSCCSGAAQHHLDFIEGNIVLCTYNKASDNNVTQLANSNYETRIKKHSSLIEYIHDNFHLLVASDFSISYKLDNEIYNFSLSSDNIKNMKSIEELPVFLYKEYGTFVKFYQNIYAKYHVSYPEIFNISIGTKPKGLTYADLVRVFTRALTLETYNFNKFSLSKIENLLHQKGLNTDFSVDQAIEQENFELLTSLLNYDNTNIQFYTINKTIDKGNLDILKAVVAHSTTKIESYNIDRAIDKGNLDILKAVVAHSTTKIESYNIDRAIDKGNLDILKAVVAHSTTKIESYNIDRAIDKGNLDILKAVVAHSTTKIESYNIDRAIDKGNLDILKAVVAHSTTKIESYNIDRAIDKGNLDILKAVVAHSTTKIESYNIDRAIDKGNLDILKAVVAHSTTKIESYNFNTVIKIGNLEMLDIILQHSYNSEELVTKYHNYTINNIMPEVNTIPTIEEDVSILGAEIV
What are the official names of this protein?
Uncharacterized protein RP612.
Protein: RL2_MICLC
Sequence: MAIRKYKPTTPGLRGSSVADFAEITRSTPEKSLLRPLHKTGGRNNTGRITTRHKGGGHKRQYRLVDFRRHDKDGVPATVAHIEYDPNRTARIALLHYADGAKRYILAPAKLKQGDVVEAGPNADIKPGNNLPMRNIPVGTTIHAVELRPGGGAKMARSAGASVQLVAREGKYAQLRLPSGEIRNVDVRCRATIGEVGNAEQSNINWGKAGRMRWKGVRPTVRGVVMNPVDHPHGGGEGKTSGGRHPVNRNGKPEGRTRRPNKESDKLIVRRRRTGKNKR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: SLB_GLOBL
Sequence: MGRFIFLSFGLLVVFVSLSGTGADCPSDWSSYEGHCYRVFQKEMTWEDAEKFCTQQRKESHLVSFHSSEEVDFVVSMTWPILKYDFVWIGLNNIWNECMVEWTDGTRLSHNAWITESECIAAKTTDNQWLSRPCSRTYNVVCKFQE
What is the function of this protein?
Binds to platelet GPIbalpha (GP1BA) and enhances platelet aggregation at low-shear stress.  At high-shear stress, blocks platelet aggregation in a dose-dependent manner.
What are the official names of this protein?
Snaclec mamushigin subunit beta.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYY_EHRCJ
Sequence: MKLESQFLSFLYSRGYFNQCTNVSALDQLMSKQCVPTYIGFDCTAKSLHVGSLVQIMILRYLQKFGHKPIVLLGNGTTKIGDPSGKDKSRTMLCSDEIEENALGIYDVLKKFIKFGSGSTDGLLVCNAEWLDDLNYIEFLRNIGRHFSVNNMLTFDSVRLRLEREQNLSFLEFNYMLLQSYDFVELNRRYNCLLQIGGSDQWGNIVSGVELGRKLQLSELFGLTTNLVLTSSGEKMGKTAQGAVWLNGDMYSPVDYWQYFRNVRDEDVGRFLKLFTELPLDKIKELELLQGHEINEAKKMLATEATKICHGEEIAKNIAADALKVFECNDDSGLSTFYVDRCDVDLGLPIIKLLQISGLEKSSSSARRLINDKGCKINDVVVLDVNYKLSLEHFCNASYVKLSCGKKRHLKIMLKSSF
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSCA_RICRO
Sequence: MQIIEIREPEQADFKPEQQIAVGIDFGTTNSLIAIAANRKVKVIKSIDDKELIPTTIDFTSNNFTIGNNKGLRSIKRLFGKTLKEILNTPALFSLVKDYLDVNSSELKLNFANKQLRVPEIAAEIFIYLKNQAEEQLKTNLTKAVITVPAHFNDAARGEVMLAAKIAGFEVLRLIAEPTAAAYAYGLNKNQKGCYLVYDLGGGTFDVSILNIQEGIFQVIATNGDNMLGGNDIDVVITQYLCNKFDLPNSIDTLQLAKKAKETLTYKDSFNNDNVSINKQTLEQLILPLVERTINIAQECLEQAGNPNIDGVILVGGATRTPLIKDELYKAFKIDILSDIDPDKAVVWGAALQAENLIAPHTNSLLIDVAPLSLGMELYGGIVEKIIMHNTPIPISVVKEFTTYVDNQTGIQFHILQGEREMAADCRSLARFELKGLPPMKAGYIRAEVTFSIDADGILSVSAYEKISNTSHAIEVKPNHGIDKTEIDIMLENAYKNAKIDYTTRLLQEAVIEAEAFIFSIERAIAEFTTLLSESEISIINSLLDNIKEAVHARDWILINNSIKEFKSKIKKSMDTKFNVIINDLLKGKNINQIK
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RR19_DRIGR
Sequence: MTRSLKKNPFVDNHLLGKIEKLNMREEKEIIVTWSRASTIIPTMIGHTIAIHNGKAHLPIYIIDRMVGHKLGEFAPTLTFRGHARNNNVSRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ACH1_LONAC
Sequence: IVGGSVTTIGQYPSMASLLFNNRQVCGGVIINNRSVLTAAHCPFGDAVSSWRFRVGSTNANSGGTVFTLSTIINHPSYNRWTLDNDISIMRAASNIGTSASVQPAGIAGSNYNLGDNQVVWATGWGATSAGGSLARFPGVNARHVQIWTVNQNTCASRYAAIGRTVTANMLCSGWLDVGGRDQCQGDSGGPLYHNRIVVAVVSRYTSWIQSNA
What is the function of this protein?
Fibrinolytic activity; shows preferential cleavage of Arg-Gly bonds in all three fibrinogen chains.  Contact with the caterpillars causes severe bleeding, due the anticoagulant effect of the protein.
What are the official names of this protein?
Achelase-1, Achelase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
Protein: CCMA_ALIF1
Sequence: MLEIRNVTCIRDERVLFERLNFTISDGELIQIEGQNGAGKTTLLRIIAGLGYADEGDIFWKNESIKQNREEFHSDLLFLGHHTGVKRELTAFENLAFYQSMHDNYNEAAIWDALARVGLAGREDVAAGQLSAGQQRRVALARLWLSNHKLWILDEPLTAIDKQGVKVLEKLFMDHAKQGGIVLLTTHQDLFIDSNELKKIRLGE
What is the function of this protein?
Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SLAP_LACAC
Sequence: MKKNLRIVSAAAAALLAVAPVAASAVSTVSAATTINASSSAINTNTNAKYDVDVTPSVSAVAANTANNTPAIAGNLTGTISASYNGKTYTANLKADTENATITAAGSTTAVKPAELAAGVAYTVTVNDVSFNFGSENAGKTVTLGSANSNVKFTGTNSDNQTETNVSTLKVKLDQNGVASLTNVSIANVYAINTTDNSNVNFYDVTSGATVTNGAVSVNADNQGQVNVANVVAAINSKYFAAQYADKKLNTRTANTEDAIKAALKDQKIDVNSVGYFKAPHTFTVNVKATSNTNGKSATLPVVVTVPNVAEPTVASVSKRIMHNAYYYDKDAKRVGTDSVKRYNSVSVLPNTTTINGKTYYQVVENGKAVDKYINAANIDGTKRTLKHNAYVYASSKKRANKVVLKKGEVVTTYGASYTFKNGQKYYKIGDNTDKTYVKVANFR
What is the function of this protein?
The S-layer is a paracrystalline mono-layered assembly of proteins which coat the surface of bacteria.
What are the official names of this protein?
S-layer protein, Surface layer protein, SA-protein.
What are the subcellular locations of this protein?
Secreted, cell wall, S-layer. Note=This bacterium is covered by a S-layer with hexagonal symmetry.
Protein: HSLU_LACDB
Sequence: MREKTPKQIVDLLDKYIVGQNEAKKSVAIALYNRYRRAQLPEDVQKDITPKNILMAGPTGVGKTEIARRLADIVDAPFVKVEATKFTEVGYVGRDVESMVRDLANEAVRIVEKEEFVKVESQAIRQANKTLVRLLVPGVKRNNRQNQMQQMQEMMQSLLAGGGMPEETEEVTDEIRNQRLSVAEKLDRGLLENEEVIIEVEQAPKANPMGDMMGQMGMDMSSMLGDMLPKKKVKRTLPVGQARKLLVQEEEKKLVNYDDIYQKAMDRAGQSGIIFIDEIDKITAADKRNSAGVSREGVQRDILPIVEGSTVSTKYGPLSTDHILFIAAGAFAESKPSDLIPELQGRFPIRVELNALTKDDFVRILKDPQNSLLKQYIALLKADGVDLVFTAEAVDKIAEIAFEVNQGTDNIGARRLATILEKLLEEVLYEGPDMEMGQITITQAYVEQKLSDIVKNKDLTKFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.