PharMolix/UniProtQA huggingface dataset:
Protein: ORF23_TTVV1
Sequence: MWTPPRNDQHYLNWQWYSSILSSHAAMCGCPDAVAHFNHLASVLRAPQNPPPPGPQRNLPLRRLPALPAAPEAPGDRAPWPMAGGAEGEDGGAGGDADHGGAAGGPEDADLLDAVAAAETLLEIPAKKPTPRAIESLEAYKSLTRNTTHRNSHSIPGTSDVVSLARKLFRECNNNQQLLTFFQQATRDPGGTPRCTTPAKKGSKKKAYFSPQSSSSDESPRGKTRSRRKAGRKAQRKRHRPSPSSSSSSCSNSESWESNSDSSSTKSKKSNKIKISTLPCYQGGGI
What are the official names of this protein?
Probable protein VP2, ORF2/3 protein.
Protein: DUT_MYCLB
Sequence: MSTSLAVVRLDPGLPLPSRAHDGDAGVDLYSVEDVKLAPGQRALVRTGLAVAIPFGMVGLIHPRSGLAVRVGLSIVNSPGTVDAGYRGEIKVALINLDPVEPLVVHRGDRIAQLLVQRVELVELVEVSSFDEAGLAETSRGDGGHGSSGGHASL
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: RL1_HALVD
Sequence: MADTIVDAVSRALDEAPGRNFRETVDLAVNLRDLDLNDPSKRVDESIVLPSGTGQDTQIVVFATGETALRAEDAADEVLGPDELEDFGDDTDAAKDLADETDFFVAEAGLMQDIGRYLGTVLGPRGKMPTPLQPDDDVVETVNRMKNTVQLRSRDRRTFHTRVGADDMTPDEIAENIDVIVRRLEATLEKGPLNIDSVYVKTTMGPSVEVPA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: SYN_PORG3
Sequence: MDKKMKRTRIADALHGGLVGQEINIKGWVRTKRGNKAVNFIALNDGSTIHNMQIVADLASFDAAQMSQITTGACIGVIGTLVESQGAGQSVEVQASAIEIYGTADPATYPLQKKGHTLEFLREIAHLRPRTNTFGVIYRIRHHMAIAIHTFFHNKGYYYFHAPLITASDCEGAGQMFQVTTLNPDSLPRTEEGQVDYRKDFFGRHTSLTVSGQLEGEMAAMALGGIYTFGPTFRAENSNTPRHLAEFWMIEPEVAFLEIEDNMDLAEEFIKYCVQWALDNCMDDISFLSEHFDKELIDRLKFVLEKPFVRLAYTEGIRILEEAVKNGVKFEFPIYWGADLASEHERYLVEVHFKTPVIMTDYPKEIKSFYMKLNDDGKTVRGMDVLFPKIGEIIGGSEREADYDKLVARANEMGVPEKDIWWYLDSRRYGTAPHSGFGLGFERLLLFVTGMSNIRDVIPFPRTPNNAEF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF1_MYCBO
Sequence: MAKKDGAIEVEGRVVEPLPNAMFRIELENGHKVLAHISGKMRQHYIRILPEDRVVVELSPYDLSRGRIVYRYK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIC_SALPC
Sequence: MSTTTLTRREQRAKAQHFIDTLEGTAFPNSKRIYVTGSQHDIRVPMREIQLSPTLIGGSKDNPQFEENEAVPVYDTSGPYGDPEVAINVQQGLAKLRQPWIDARNDSEELDDRSSAYTRERLADDGLDDLRFTGLLTPKRAKAGKCVTQLHYARKGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMNFGARLPENITPEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHKENFLFEHFREICEICAAYDISLSLGDGLRPGSIQDANDEAQFSELHTLGELTKIAWEYDVQVMIEGPGHVPMHMIQRNMTEELESCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQAIEVGMADMSENFRAKGGEIYLKREEV
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: PYRH_BURP6
Sequence: MPNAYKRVLLKLSGEALMGDDAFGINRATIERMVADIAEVVRLGTQLAVVIGGGNIFRGVAGGAAGMDRATADYMGMLATMMNALALQDAMRHAGIEARVQSALRMDQVVEPYIRPRAIRQLEEGKVVIFAAGTGNPFFTTDTAAALRGSEVGAEVVLKATKVDGVYSADPKKDPSATRYSSISFDEAIGRNLQVMDATAFALCRDQKLPIRVFSINKPGALKRIVQGEDEGTLVHV
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EXOY_SINFN
Sequence: MKSATRSATTAFFIPQETGAIRPIGGISKRSFDVLIAILALIALSPLFLLVMGLVKFSDGGSIFYGHRRIGHNGQTFKCLKFRTMMENGDRVLQEFFKSNPAAYEEWRTTRKLQDDPRVTVVGSVLRKLSLDELPQLLNIIRGEMSIVGPRPVVEDELELYDSAAEFYLRSRPGLTGLWQISGRNDVSYATRVAFDTHYVQNWSLLADLVIVFKTIPAVCLSRGSY
What is the function of this protein?
Needed for the addition of the first sugar (galactose) to the isoprenoid carrier.  May function as a sugar transferase.
What are the official names of this protein?
Exopolysaccharide production protein ExoY.
What is the protein family that this protein belongs to?
Belongs to the bacterial sugar transferase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RL6_ACHLI
Sequence: MSRIGNKVIVVPAGVTVDIKEGNFLTVKGPKGQLEKQLNSDLSITLEGNLLTVKRPNNEMFMRKIHGTTRALLFNMVHGVSEGFSKKLEIKGVGYRAQLQGNTLVLQLGFSHNIEMPLPEGISLDVPKNTEITVNGIDKAVVGQFAAEIRKHRKPEPYKGKGIRYVDEYVARKAGKTAK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: EMC3_YEAS1
Sequence: MLLDDQLKYWVLLPISIVMVLTGVLKQYIMTLITGSSANEAQPRVKLTEWQYLQWAQLLIGNGGNLSSDAFAAKKEFLVKDLTEERHLAKAKQQGGSQAGEVPNPFNDPNMSNAMMNMAKGNMASFIPQTIIMWWVNHFFAGFILMQLPFPLTAKFKEMLQTGIICQDLDVRWVSSISWYFISVLGLNPVYNLIGLNDQDMGIQAGIGGPQGPQGPPQSQVDKAMHAMANDLTIIQHETCLDNVEQRVLKQYM
What is the function of this protein?
The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER).
What are the official names of this protein?
ER membrane protein complex subunit 3, Altered inheritance rate of mitochondria protein 27.
What is the protein family that this protein belongs to?
Belongs to the EMC3 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: YIDD_AGRFC
Sequence: MCGEPGCRHEQTAVKAGRSRNWAGSFAKTPGRLFGVGFIRLYQLTLSGFVGNSCRHIPTCSEYGYEAIARHGLWAGGWMALFRVARCGPGGTSGLDPVPEELDGSKRWWTPWRYWSRHR
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS6_GRABC
Sequence: MPLYESVLIARNDVTQQQVESVADHVASLIEAEGGAIKKREYWGLRTLAYRIKKNRKGHYMLLGLDAKPATITEVERQLRLNEDVLRFMTIRVEEIDDVPSVILSRKSDDRERGFRGPKPPGRFESGRKRGYDDREEFRARAGGDDDDRGLDQE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: EFG_BACFR
Sequence: MAKNDLHLTRNIGIMAHIDAGKTTTSERILFYTGLTHKIGEVHDGAATMDWMEQEQERGITITSAATTTRWKYAGDTYKINLIDTPGHVDFTAEVERSLRILDGAVAAYCAVGGVEPQSETVWRQADKYNVPRIAYVNKMDRSGADFFEVVRQMKAVLGANPCPVVIPIGAEENFKGLVDLIKMKAIYWHDETMGADYTIEEIPANLVDEANEWRDKMLEKVAEFDDALMEKYFDDPSTITEEEVLRALRNATVQMAVVPMLCGSSFKNKGVQTLLDYVCAFLPSPLDAENVVGTNPDTGAEEDRKPSEDDKTSALAFKIATDPYVGRLTFFRVYSGKIEAGSYIYNSRSGKKERVSRLFQMHSNKQNPVEVIGAGDIGAGVGFKDIHTGDTLCDETAPIVLESMDFPEPVIGIAVEPKTQKDMDKLSNGLAKLAEEDPTFTVKTDEQTGQTVISGMGELHLDIIIDRLKREFKVECNQGKPQVNYKEAITKTVNLREVYKKQSGGRGKFADIIVNIGPVDEDFTQGGLQFVDEVKGGNIPKEFIPSVQKGFQTAMKNGVLAGYPLDSLKVTLVDGSFHPVDSDQLSFEICAIQAYKNACAKAGPVLMEPIMKLEVVTPEENMGDVIGDLNKRRGQVEGMESSRSGARIVKAMVPLAEMFGYVTALRTITSGRATSSMVYSHHAQVSSSIAKAVLEEVKGRADLL
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_TERTT
Sequence: MKRVVYPGTFDPITNGHIDLVQRASKLFDSVVIAVAASNRKGPLFTLEERVSLAQKALSHLSNIEVCGFDCLLKDLVEEKQAYGVVRGLRAVSDFEYEFQLANMNRALAPSMESLFLTPAEHLSYISSSLVKEIASLGGDVSKFVPKLVQSALTDKYNELKA
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAPK6_ORYSJ
Sequence: MEKYELLKDIGSGNFGVARLMRNRETKELVAMKYIPRGLKIDENVAREIINHRSLRHPNIIRFKEVVLTPTHLAIVMEYAAGGELFDRICSAGRFSEDESRYFFQQLICGVSYCHFMQICHRDLKLENTLLDGSPAPRLKICDFGYSKSSLLHSKPKSTVGTPAYIAPEVLSRREYDGKMADVWSCGVTLYVMLVGAYPFEDPDDPKNFRKTIGRIVSIQYKIPEYVHISQDCRQLLSRIFVANPAKRITIREIRNHPWFMKNLPRELTEAAQAKYYKKDNSARTFSDQTVDEIMKIVQEAKTPPPSSTPVAGFGWTEEEEQEDGKNPDDDEGDRDEEEGEEGDSEDEYTKQVKQAHASCDLQKS
What is the function of this protein?
May play a role in signal transduction of hyperosmotic response (Probable).  Can phosphorylate ABI5 in vitro (PubMed:21055780).  Can phosphorylate BZIP46 in vitro (PubMed:22301130).
What are the official names of this protein?
Serine/threonine-protein kinase SAPK6, Osmotic stress/abscisic acid-activated protein kinase 6, stress-activated protein kinase 6, OsSAPK6.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: HIS1_PSEU2
Sequence: MLTIALSKGRILDDTLPLLAEAGIVPTENPDKSRKLIIPTTQADVRLLIVRATDVPTYVEHGAADLGVAGKDVLMEYTGQGLYEPLDLQIAKCRLMTAGAIGAVEPKGRLRVATKFVNVAKRYYAEQGRQVDIIKLYGSMELAPLIGLADKIIDVVDTGNTLRANGLEPQELIATISSRLVVNKASMKMQHARIQALIDTLRKAVESRHRS
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURD_RUMCH
Sequence: MNNKLEQFKKDVKNKRVAVMGIGVSNIPLIKYLVSFGVDVTAFDKSTEEKLTDAFNELKGLPVKYSLGPDYLSRLNGFDMIFRTPGMRPDLPELVEAVANGAELTSEMEVFLKLCPAQVFAVTGSDGKTTTTTLIYKTLSEEGFKCWLGGNIGTPLLSKIDDVAETDKVILELSSFQLMTIKDCPSVAVITNISPNHLDVHKSLQEYIDAKKNIFINQNENDKLVLNFDNEITKSFNYEARGEYVYFSRLNNINEGVVYQNGRIIVKKENSITEIIEGDKIKIPGVHNIENYMAATAATIDYVKPETIARIASSFNGVEHRIELVRELNGVKFYNSSIDSSPSRTIAALKTFKDKVILIAGGKDKGIPYDSMGEIITEKVKCLLLIGATASRIEEAYKNYLQQRDLENDIKIIHCDTYQEVVQKAHAEAEQGDCIILSPASTSFDMFKNFEHRGNVFKELVNNLK
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GR58C_DROME
Sequence: MNQYFLLHTYFQVSRLIGLCNLHYDSSNHRFILNHVPTVVYCVILNVVYLLVLPFALFVLTGNIYHCPDAGMFGVVYNVVALTKLLTMLFLMSSVWIQRRRLYKLGNDLMKMLHKFRFNLGNDCRNRCLCKGLLTSSRFVLLTQQLLTRDSVVNCESNSSLRQAMVPYQSAAIVYALIMILLMSYVDMTVYMVEVAGNWLLVNMTQGVREMVQDLEVLPERNGIPREMGLMQILAAWRKLWRRCRRLDALLKQFVDIFQWQVLFNLLTTYIFSIAVLFRLWIYLEFDKNFHLWKGILYAIIFLTHHVEIVMQFSIFEINRCKWLGLLEDVGNLWDINYSGRQCIKSSGTILSRKLEFSLLYMNRKLQLNPKRVRRLHIVGLFDLSNLTVHNMTRSIITNVLVLCQIAYKKYG
What is the function of this protein?
Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
What are the official names of this protein?
Putative gustatory receptor 58c.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr10a subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RIMO_BEII9
Sequence: MAHPVMTFDKPSSASPKISFVSLGCPKALVDSERIITRLRAEGYELTKSHRGADAVIVNTCGFLDSAKAESLAAIGEAAAENGKIIVTGCMGAEPESLQTAYPDLFAITGPQAYESVMEAVHAAIAPPDNPFTELVPPQGIKLTPRHYAYLKISEGCNNRCSFCIIPHLRGDLVSRPIGEILQEAEKLVSAGVKEILVVSQDTSAYGVDLKYAETLYGDRTLRSKFIDLARELGSLGVWVRLHYIYPYPHVDAVLDLMAEGKILPYLDIPFQHASRNVLRAMRRPGDQEKTLSRIEEWRKLCPDLTLRSTFIVGFPGETEDDFQILLDWLSEAKLDRVGAFKYEPVADAPANDLDLTPVAPEVQTRRYQRFMEHQQKISARRLREKIGKHVSVIIDEASPKAAIGRTKGDAPSIDGKVHITTHRPLRVGDIVKVKIEAADAYDLHGKAV
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTK_HUMAN
Sequence: MESEDLSGRELTIDSIMNKVRDIKNKFKNEDLTDELSLNKISADTTDNSGTVNQIMMMANNPEDWLSLLLKLEKNSVPLSDALLNKLIGRYSQAIEALPPDKYGQNESFARIQVRFAELKAIQEPDDARDYFQMARANCKKFAFVHISFAQFELSQGNVKKSKQLLQKAVERGAVPLEMLEIALRNLNLQKKQLLSEEEKKNLSASTVLTAQESFSGSLGHLQNRNNSCDSRGQTTKARFLYGENMPPQDAEIGYRNSLRQTNKTKQSCPFGRVPVNLLNSPDCDVKTDDSVVPCFMKRQTSRSECRDLVVPGSKPSGNDSCELRNLKSVQNSHFKEPLVSDEKSSELIITDSITLKNKTESSLLAKLEETKEYQEPEVPESNQKQWQSKRKSECINQNPAASSNHWQIPELARKVNTEQKHTTFEQPVFSVSKQSPPISTSKWFDPKSICKTPSSNTLDDYMSCFRTPVVKNDFPPACQLSTPYGQPACFQQQQHQILATPLQNLQVLASSSANECISVKGRIYSILKQIGSGGSSKVFQVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYMVMECGNIDLNSWLKKKKSIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGMLKLIDFGIANQMQPDTTSVVKDSQVGTVNYMPPEAIKDMSSSRENGKSKSKISPKSDVWSLGCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRISIPELLAHPYVQIQTHPVNQMAKGTTEEMKYVLGQLVGLNSPNSILKAAKTLYEHYSGGESHNSSSSKTFEKKRGKK
What is the function of this protein?
Phosphorylates proteins on serine, threonine, and tyrosine (PubMed:18243099, PubMed:29162720).  Probably associated with cell proliferation (PubMed:18243099).  Phosphorylates MAD1L1 to promote mitotic checkpoint signaling (PubMed:29162720).  Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint (PubMed:18243099).
What are the official names of this protein?
Dual specificity protein kinase TTK, Phosphotyrosine picked threonine-protein kinase, PYT.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: ERD12_SCHPO
Sequence: MDLEVVEFPLHHKLALPFRIGLLVIVGTWLWSVCYHLIYILNRYQPISPNPRGSLNSKWYHLLQIPLSNRHTDLEENTEFKANLVSPVDFHAGYCFAAILSISWATGFILFLKKTQGDIGGLYSHPIYPLLWVITAFILIVFPFPWRYRSSQRGLRKSIIRVFLFFQADFRSPYKDFIVSEIFTSYAKALGDFYIFGCVLQGHISKFTLRPDLKCDGTFFVPLAMAYPFIVAILQCLHYGLSRRKHTFKINLLSALKHATALPVIYLSAIIHAKQTKFTLTSGHGYLFWLWILSALLSSAYTFLWDVFIDWRIRFPFHKSINHKRFPMFIYAIGCFINFILRVTWSMKLHPRLHQFHEYEMGIFSFEMLEILRRFLWLFFHLDAISS
What are the official names of this protein?
Protein ERD1 homolog 2.
What is the protein family that this protein belongs to?
Belongs to the ERD1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MCM6_CAEBR
Sequence: MDNIISGQAQKVEDVDGTRVQNEFSKFLKSFKGDKNELQYKTAMKELVQPEKNTIFVDMQHLYKFSNNLATTIELQYYRVYPFMCEALHLATLDGCDENERQQMFKKQLYVSLYNLDAKTKVRELSADKVGGLVRIAGQIVRTHPVHPELSRACFVCEDCGVSTRDVQQQFRYTQPTKCANPQCMNRTRFSLDVNSSTFVDFQKIRIQETQAELPRGSIPRTVDVIVRGEMVETVQPGDKCDIVGTLIVIPDIAQLSTPGLRAETSNQNRGRATDKSEGITGLKALGVRDLTYKMAFLACHIQQTESLVGGDASGAMEENDYLELWTKMSPEDRSVLKQMSDDKKIEKNIVDSLFPNIYGNHEVKLGVLLMLLGGVAKKSKDEGTSLRGDINVCLVGDPSTAKSQVLKAVEEFSPRAIYTSGKASSAAGLTAAVVKDEESFEFVIEAGALMLADNGVCCIDEFDKMDVKDQVAIHEAMEQQTISITKAGVKATLNARASILAAANPVGGRYDRSRPLKYNVQMSAPIMSRFDLFFVLVDECNEVTDYAIARRILDNHRSISEHTERNTVYKIDDIKKYIAFARCFKPKISDKAAEALVREYKKLRMSDSNNAATSSWRITVRQLESLVRLSEALARLHCGKEVLEQHVEKAAELLNKSIVRVEQPDIALDEDDFDNNIVIVEANKENQGGDDDMEHDGEKDETAKVDPAKLKISFKEYKQLSDVLVLHMRADEESQGEEEYDGVKQSALVEWYLTTIEGEMETEEDFNVQKTVCERVIHRLVHQDHILLEVEPGEDPTLCVHPNYVVSDE
What is the function of this protein?
Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells.  Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.  The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit.  The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
What are the official names of this protein?
DNA replication licensing factor mcm-6.
What is the protein family that this protein belongs to?
Belongs to the MCM family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HBA_EQUZE
Sequence: MVLSAADKTNVKAAWSKVGGNAGEFGAEALERMFLGFPTTKTYFPHFDLSHGSAQVKAHGKKVGDALTLAVGHLDDLPGALSNLSDLHAHKLRVDPVNFKLLSHCLLSTLAVHLPNDFTPAVHASLDKFLSTVSTVLTSKYR
What is the function of this protein?
Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1.  Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.
What are the official names of this protein?
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RUVA_BACC1
Sequence: MFEYVTGYVEYVGPEYVVIDHNGIGYQIFTPNPYVFQRSKQEIRVYTYHYVREDIMALYGFKTREERLLFTKLLGVSGIGPKGALAILASGQTGQVVQAIEHEDEKFLVKFPGVGKKTARQMILDLKGKLADVVPDAFVDLFSDEERFDEKKGSSAELDEALEALRALGYAEREVSRVVPELLKESLTTDQYIKKALSLLLNGKR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: IF2_YERPA
Sequence: MTDVTVKSLAAEIQTPVDRLVQQFADAGIKKSDVDSVTQQEKEILLAHLNREHGSVPNKLTLQRKTRSTLNIPSTGGKSKSVQIEVRKKRTYVNTPEAEQAKAEEQAQREAEATAQKIAEEKAKREAEEQAKREAAEKAKRQAAEKEKVTNQQTDEKTKPAQTDKARREAEAAELKRSVEEETRRKVEEDAKRVAEEARKMAAENEGKWPEPVAEQTESADYHVTTSQHARAAEDENDAKVEGDRRSRTRGGKATKQKKGNKLSESKADREEARAVGRKGKRKPSTLQQSFNKPVVAVNRDVVIGETVTVAELANKMAVKGSQVIKAMMKLGAMATINQVIDQETAQLVAEEMGHKVILRRENELEEALMSDRDIGVEAAAEHRAPVVTIMGHVDHGKTSLLDYIRSTKVASGEAGGITQHIGAYHVETENGMITFLDTPGHAAFTSMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAANVPVVVAVNKIDKPEADPDRVKTELSQYGIQPEEWGGESQFINVSAKAGIGIDELLNAILLQAEVLELKAVRTGMANGVVIESFLDKGRGPVATVLVQQGTLNKGDIVLCGFEYGRVRAMRDELGRDITSVGPSIPVEILGLSSVPAAGDEVTVVRDEKKAREVALYRQGKFREVKLARQQKSKLENMFANMTEGEVSELNIVIKSDVQGSCEAICDSLEKLSTDEVKVRIVGSGVGGITETDATLAAASGAIILGFNVRADASARRVVETEGLDLRYYSVIYSLIDEVKQAMSGMLAPEYKQQIIGLAEVRDVFKSPKFGAIAGCMVTEGVIKRNNPIRVLRDNVVIYEGELESLRRFKDDVSEVRNGMECGIGVKNYNDVRTGDVIEVFEIIEIKRTIA
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: O236E_CONTE
Sequence: MQKLIILLLVAAVLMSAQAVLQEKRPKEKIKFLSKRKTDAEKQQKRLCPDYTEPCSHAHECCSWNCYNGHCTG
What are the official names of this protein?
Conotoxin Gla(3)-TxVI, Conotoxin Glu7/Gla(3)-TxVI, Conotoxin TxMEKL-04111.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O2 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPD_CHLTE
Sequence: MSSAIASRRYAVALLEVAVEGNFLEKVTEDLQKIQEVLSGSHELVLALKSPLINVDLKSKILEEIFRNKVDEKTMVFIKLLAHKKRAALLAGVISEFNALIDERNGVINADVKSAIKLSDEQAKELVNSLSVRTGKKIRAKMRLDENLIGGVTVKIGDTIIDGSISHQLEMLRHSLVAQPA
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS11_SYNC1
Sequence: MAKGSKRVVRKRAEKKNIANGIAHIQATFNNTIVTITDIAGNVISWSTCGTMNFKGSRKSTPFAAQIAAEDAAKKAMEHGLRSVEVRVKGPGSGRESALRALSSAGLNISVIKDVTPIPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.