PharMolix/UniProtQA huggingface dataset:
Protein: OSTCN_BISPR
Sequence: YLDHGLGAPAPYPDPLEPKREVCELNPDCDELADHIGFQEAYRRFYGPV
What is the function of this protein?
Constitutes 1-2% of the total bone protein.  It binds strongly to apatite and calcium (By similarity).
What are the official names of this protein?
Osteocalcin, Bone Gla protein, BGP, Gamma-carboxyglutamic acid-containing protein.
What is the protein family that this protein belongs to?
Belongs to the osteocalcin/matrix Gla protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: METK_BURCH
Sequence: MANDYLFTSESVSEGHPDKVADQISDAILDAILEQDKYSRVAAETLCNTGLVVLAGEITTTANIDYIQIARDTIKRIGYDNTDYGIDYKGCAVLVAYDKQSPDIAQGVDRAHDDNLDQGAGDQGLMFGYACDETPELMPLPIYLSHRLVERQASLRRDGRLQWLRPDAKSQVTVRYVDGKPDSIDTVVLSTQHAPDIELPALREAVIEEIIKPTLPAELIKGDIKFLVNPTGRFVIGGPQGDCGLTGRKIIVDTYGGAAPHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLASRALIQVSYAIGVAEPTSVMVNTFGTGRVSDAVITKLVREHFDLRPKGIIKMLDLLRPIYEKTAAYGHFGREEPEFSWEATDKALALAEAAGVEPTARVA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_MOOTA
Sequence: MECSINNQQADYPVGEELLSTLNRVLQAAAAAEGVAGEAEVSLTLVDDAAIKELNRTYRGVDAPTDVLSFALEEKGPDEPAYADPGGDKLLGDIIISVPTAVRQAGEYGHSLARELAFLAVHGFLHLLGYDHDTAAGAADMEARQEAILAGVGLRR
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDUA3_GORGO
Sequence: MAARVGAFLKNAWDKEPVLVVSFVVGGLAVILPPLSPYFKYSVMINKATPYNYPVPVRDDGNMPDVPSHPQDPQGPSLEWLKKL
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3, Complex I-B9, CI-B9, NADH-ubiquinone oxidoreductase B9 subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFA3 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: PPE23_MYCTO
Sequence: MTLDVPVNQGHVPPGSVACCLVGVTAVADGIAGHSLSNFGALPPEINSGRMYSGPGSGPLMAAAAAWDGLAAELSSAATGYGAAISELTNMRWWSGPASDSMVAAVLPFVGWLSTTATLAEQAAMQARAAAAAFEAAFAMTVPPPAIAANRTLLMTLVDTNWFGQNTPAIATTESQYAEMWAQDAAAMYGYASAAAPATVLTPFAPPPQTTNATGLVGHATAVAALRGQHSWAAAIPWSDIQKYWMMFLGALATAEGFIYDSGGLTLNALQFVGGMLWSTALAEAGAAEAAAGAGGAAGWSAWSQLGAGPVAASATLAAKIGPMSVPPGWSAPPATPQAQTVARSIPGIRSAAEAAETSVLLRGAPTPGRSRAAHMGRRYGRRLTVMADRPNVG
What are the official names of this protein?
Uncharacterized PPE family protein PPE23.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PPE family.
Protein: ALR_LISMO
Sequence: MVTGWHRPTWIEIDRAAIRENIKNEQNKLPESVDLWAVVKANAYGHGIIEVARTAKEAGAKGFCVAILDEALALREAGFQDDFILVLGATRKEDANLAAKNHISLTVFREDWLENLTLEATLRIHLKVDSGMGRLGIRTTEEARRIEATSTNDHQLQLEGIYTHFATADQLETSYFEQQLAKFQTILTSLKNRPTYVHTANSAASLLQPQIGFDAIRFGISMYGLTPSTEIKTSLPFELKPALALYTEMVHVKELAPGDSVSYGATYTATEREWVATLPIGYADGLIRHYSGFHVLVGGELAPIIGRVCMDQTIIKLPREFQTGSKVTIIGKDHGNTITADDAAQYLDTINYEVTCLLNERIPRKYIH
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: UL41_HCMVA
Sequence: MYHHCCYGIITTLRPGLWCVLFFVHARHDTLLPHRQQHRRLRRHERLHRHDRRGLFRFRGLYSHLLLHVESFLRAAKDLPPPGYRVGRRGDHGLGKAPDGVGYRLLKEAIKIWEFPCLRLHDGRLFLRLGLCLVVIRARTF
What are the official names of this protein?
Uncharacterized protein UL41.
Protein: OST6_YEAST
Sequence: MKWCSTYIIIWLAIIFHKFQKSTATASHNIDDILQLKDDTGVITVTADNYPLLSRGVPGYFNILYITMRGTNSNGMSCQLCHDFEKTYHAVADVIRSQAPQSLNLFFTVDVNEVPQLVKDLKLQNVPHLVVYPPAESNKQSQFEWKTSPFYQYSLVPENAENTLQFGDFLAKILNISITVPQAFNVQEFVYYFVACMVVFIFIKKVILPKVTNKWKLFSMILSLGILLPSITGYKFVEMNAIPFIARDAKNRIMYFSGGSGWQFGIEIFSVSLMYIVMSALSVLLIYVPKISCVSEKMRGLLSSFLACVLFYFFSYFISCYLIKNPGYPIVF
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity (PubMed:11580295).  Can participate in redox reactions and is able to catalyze dithiol-disulfide exchange reactions with other proteins, albeit with relatively low efficiency.  May form transient disulfide bonds with nascent polypeptides in the endoplasmic reticulum and thereby promote efficient glycosylation (PubMed:19549845).
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST6, Oligosaccharyl transferase subunit OST6, Oligosaccharyl transferase 37 kDa subunit, OTase 37 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the OST3/OST6 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: FTHS_STRMU
Sequence: MKTDIEIAQSVDLRPITNVVKKLGFDFDDLELYGKYKAKLTFDKIKAVEENAPGKLVLVTAINPTPAGEGKSTITIGLADALNKIGKKTMIAIREPSLGPVMGIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRRIIWKRVVDLNDRALRHVTVGLGSPINGIPREDGFDITVASEIMAILCLATNVEDLKERLANIVIGYRFDRSPVYVRDLEVQGALALILKEAIKPNLVQTIYGTPAFVHGGPFANIAHGCNSVLATSTALRLADYTITEAGFGADLGAEKFLDIKAPNLPTSPDAVVIVATIRALKMNGGVAKDALNQENVEAVKAGFANLARHVENMRKYGVPVVVAINEFITDTNDEIAVLRNLCAAIDVPVELASVWANGADGGVDLANTLINTIENNPSHYKRLYDNNLSVEEKVTEIAKEIYRADKVIFEKKAKTQIAQIVKNGWDNLPICMAKTQYSFSDDPKLLGAPTGFDITIRELVPKLGAGFIVALTGDVMTMPGLPKKPAALNMDVAADGTALGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: SYDND_DESAL
Sequence: MADLLGSMRRTHNCGVLRKEDTGKTVTLMGWAQRWRDHGGVIFIDLRDRYGVTQVVFNPENNAEVHKLADSIRSEWVIAVQGEVLERPDGMVNPKMETGEIEVMVSDLKILNKSKTPPFMVEDNAEVSENLRLEYRYLDLRRPRIAKNIMLRHQVGACVRAFLNENEFLDIETPVLTKSTPEGARDYLVPSRVNTGLFYALPQSPQLFKQLLMVAGYDRYYQIVRCFRDEDLRADRQPEFTQIDLEMSFVGEEDVMGIAEQMIAKVFKDVMGKEVKTPFDRLTYKDAMDRYGLDKPDLRFDLELKEVSSIVEGSDFKVFASVVKKGGMVKAMNAKGCAHFSRKVIDDLTAFVAVYGAKGLAWIKVKEDGSWQSPIAKFFTDDEKAAMAQTLDMAPGDLIFFVADNVKVTNDALGHLRNRVAKELGLIDENEFRFVWVTEFPLVEYDETDKRYVALHHPFTAPMEEDLDLLESDPGAVRSRAYDMVLNGTELGGGSIRIHQPEMQEKVFNMLGLGQEEAEEKFGFLLKALAFGAPPHGGLAFGFDRLIMLLSGENSIRDIIPFPKTQKAACLLTDAPSEVAFEQLAELALRIKKDPAS
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSM18_YEAS7
Sequence: MQPIIKGAVSSTFKRALYNFGIKEKKSVNIEMGRTQQTKKIDQSLSKKLPKGTIYDPFDFSMGRIHLDRKYQANKNSNRNDIMKSGANPLEFYARPRILSRYVTSTGRIQHRDITGLSAKNQRRLSKAIRRCQAIGLM
What are the official names of this protein?
37S ribosomal protein RSM18, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: YFE9_SCHPO
Sequence: MSKMGSSSMGELQDGITQEDSIEKKSKNVASHGEKRKVKRKKEDLSMDGSNDGVKDSPDSNDDSQSKKKKKKKLKKSQQPLNEENYPRLQTTENNLQKPLKISDLQELVFWCLADGQAPSWVLVRNKQMIHRAVILLVPGLEPSQFGFQPVRGNKHSFLLPNLLNENGPIQLPDFCEVFDRAWPTRSPGDRFRVFSPVNAFLQSPLSNEQKKKRDKETRAMASFSKPSDYLMSYESFIEDEYPLHPTVMKGEEVTQPSGWVASAGDFHSPPINPKILAIDCEMVRTENGLEIARVTIVDMKSEVIYDEFVKPESPVTDYVTQYSGITEEKLRNVTTVLSDVQSYLKKTVDNNTVLLGHSLNSDLNCLKFTHPHIIDTANIYNHTRGPPSKPSLKWLATKWLRREIQKAGALGHDSAEDALACVDLLKLKVKNGPAFGLFNQDFESIFHRLSRQQPTPLIGAIADYGNPESCIGKAAHKSVSCANDDEVVSAVVSLSDMHNFVWGRFRELEHAAMWNANRNTKQENNSDTDTENDSVEEDQVTSYSSALERFNRRIRLLYDSLPKGSLLLLYTGTGNPIEMSKLNAIRQQFRKEYQTKKWDELSVKWTDEENMKYISAVENTRNGLSFMTIK
What are the official names of this protein?
Uncharacterized exonuclease C637.09.
What is the protein family that this protein belongs to?
Belongs to the REXO1/REXO3 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: OCE1_LEPPE
Sequence: GLLDTLKGAAKNVVGSLASKVMEKL
What is the function of this protein?
Antibacterial peptide that ihibits reference strains of both Gram-negative bacteria (E. coli, E. cloacae, K. pneumoniae, P. aeruginosa) and Gram-positive bacteria (S. aureus, S. epidermidis, E. faecalis, Streptococcus group B) with relatively low potencies (MIC=25-200 uM).  The peptide shows very low hemolytic activity against human erythrocytes.  Wheel projection demonstrates the amphipathicity of the alpha-helices is low which may explain the low antibacterial potency.
What are the official names of this protein?
Ocellatin-P1, Pentadactylin.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Ocellatin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SRY_CALUR
Sequence: MFGVLNSDDHRAAIQQRNILAFGRTSSELWTSNPTSNYWCETRGNGRDSGQNRVRRPMNAFMVWSRDQRRKVALENPQMQNSEISKQLGYQWKMLTEAEKWPFFEEAQRLQAMHREKYPDYKYRPRRKALPQKSDKFLPAASSTLLCRQVLVDKWYPFTYRDSCSRATHSHMEDQLSSSQPVNIANSLLQQEHHYSSTSLRGSPETLATHLSADPPFYPK
What is the function of this protein?
Transcriptional regulator that controls a genetic switch in male development.  It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells.  Involved in different aspects of gene regulation including promoter activation or repression.  Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.  SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending.  Also involved in pre-mRNA splicing (By similarity).  In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity).
What are the official names of this protein?
Sex-determining region Y protein, Testis-determining factor.
What is the protein family that this protein belongs to?
Belongs to the SRY family.
What are the subcellular locations of this protein?
Nucleus speckle. Cytoplasm. Nucleus.
Protein: PRP5_COCIM
Sequence: MARETRSPSPVGSTHSSSKRSRRNDDYLDRSRRDDGRGHRRSRSPPRRHRDRDWDRHRDRDRDRDRDRVRDRERGRDRERDRDTYRKSDRSVDRRDYRDDVRDDTSYRPSRRDRSRPRYHSRDREDGREYRHRSRDRRRRDDSADSKSIAKRNESRDRVSSKDFTGKSREVSKPSTPAPPIAQTDEEKKAERLAKLEAWKQKQAAEKERKQKELAAAGGARSILAEIDKRSTLRQAGVSQETPAPQESESASAKKFDPKTITKNAAAQPERLSLLGNDVAVPNTTTSSEVAGRNGADSTRIAPLKPRGNVSGFGFGAKSAAELEKASHKRALDFGDEESSRKKLMKLPDPSLEDNDTPNGTVNGAEEEEDDDGDIDMQDGGTEEENAAAARAAAEKREERLQNQTVALESQPEQQPETLETDQNGSAEPMDVEDEEEIDPLDAFMSGLKDSVTVDASKYRKNVSKPKQEPEAIFGDEDDVDLKAMDFEADDFLAITSKTRKKKDLPTVNHETIDYEPFRKSFYTEPVDLAELNDEEVAALRLELDGIKVRGVDVPKPVQKWSQCGLGVQTLDVIRKLGYEQPTSIQSQAIPAIMSGRDVIGVAKTGSGKTIAFLLPMFRHIKDQRPLENMEGPVGLIMTPTRELATQIHKECKPFLKALNLRAVCAYGGAPIKDQIAELKRGAEIIVCTPGRMIDLLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMKIISNIRPSRQTVLFSATFPRNMEALARKTLTKPVEIIVGGRSVVAQEITQIVEVRPENTKFVRLLELLGNLYSDDNNEDARALIFVDRQEAADGLLRDLMRKGYPCMSIHGGKDQVDRDSTIDDFKAGIFPVLIATSVAARGLDVKQLKLVINYDAPNHLEDYVHRAGRTGRAGNTGTAVTFLTEEQERYSVDIAKALKQSGQSVPEAVQKMVDSFLEKVKSGKEKASASGFGGKGLERLDQERDAARNRERKTYKTGEEGEEDEEKEKKEKDKGEELFAKAASAVQSSSAPTPSATPGVPKGIDLDGKITVHKTERATPSTTGTNPLDKVGSAVADIHARLNKAGVMRSGVPIDNKGPDAGAFHATLEINDFPQKARWAVTNRTNVAKILEATGTSITTKGSYYPPGKEPGPNENPKLYILVEGDTELVVTNAMRELMRLLKEGTIAAADSEARAPASGRYNVL
What is the function of this protein?
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing.  Catalyzes an ATP-dependent conformational change of U2 snRNP.  Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
What are the official names of this protein?
Pre-mRNA-processing ATP-dependent RNA helicase PRP5.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: METK_BORPA
Sequence: MANNDFLFTSESVSEGHPDKVADQISDAILDAIFTQDPNARVAAETLCNTGLVVLAGEITTTANVDYIQVARDTIRHIGYDNTEYGIDYKGCAVLVAYDKQSPDIAQGVDRSSEDYLNQGAGDQGLMFGYACDETPDLMPAPIWYAHRLVQRQSELRKDGRLPWLRPDAKSQVTFRYVDGRPAEVDTVVLSTQHSPEISQASIREAVIEDIIKPSFPEGLITPKTKFLVNPTGRFVIGGPQGDCGLTGRKIIVDTYGGACPHGGGAFSGKDPSKVDRSAAYAARYVAKNVVAAGLARQCQVQVSYAIGVAEPINITVYTEGTGVIPDEQIAKLVREHFDLRPKGIVNMLDLLRPIYTKTAAYGHFGRSEPEFSWEATDKAAALKQGA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRC_STRAW
Sequence: MADPSSYRPKPGEIPDSPGVYKFRDEHHRVIYVGKAKSLRQRLASYFQDLAGLHPRTRTMVTTAASVEWTVVSTEVEALQLEYSWIKEYDPRFNVKYRDDKSYPYLAVTMNEEFPRVQVMRGHKRKGVRYFGPYGHAWAIRDTVDLLLRVFPVRTCSAGVFKNAARTGRPCLLGYIGKCSAPCVERVSAEEHRELAEEFCDFMAGRTGTYIRRLERQMTDAAEEMEYEKAARLRDDIGALKKAMEKNAVVLADATDADLIAVAEDELEAAVQIFHVRGGRVRGQRGWVTDKVEAVTTADLVEHALQQLYGEETGDSVPKEVLVPALPDPVEPVQEWLTGRRGSIVSLRIPQRGDKKSLMETVQRNAQQSLALHKTKRASDLTTRSRALEEIAEALDLDSAPLRIECYDISHLQGDDVVASMVVFEDGLQRKSEYRRFQIKSFEGQDDVRSMHEVITRRFRRYLSEKERTGEWADGDLKDGELKDDEGRPKRFAYPPQLVVVDGGQPQVAAAKRALDELGIDDIAVCGLAKRLEEVWLPDDGDPVVLPRTSEGLYLLQRVRDEAHRFAITYQRTKRAKRFRASPLDDVAGLGETRKQALIKHFGSVKKLRSATIDQICEVPGIGRKTAETIAVAFAQAAPAVPAVNTATGEIMEDEEPGTTAGSSQEPVSAGTSDERRGQET
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMB_ECOL5
Sequence: MLQVYLVRHGETQWNAERRIQGQSDSPLTAKGEQQAMQVATRAKELGITHIISSDLGRTRRTAEIIAQACGCDIIFDSRLRELNMGVLETRNIDSLTEEEENWRRQLVNGTVDGRIPEGESMQELSDRVNAALESCRDLPQGSRPLLVSHGIALGCLVSTILGLPAWAERRLRLRNCSISRVDYQESLWLASGWVVETAGDISHLDAPALDELQR
What are the official names of this protein?
Probable phosphoglycerate mutase GpmB, PGAM, Phosphoglyceromutase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. GpmB subfamily.
Protein: CLPS_SALTY
Sequence: MGKTNDWLDFDQLVEDSVRDALKPPSMYKVILVNDDYTPMEFVIDVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCTLEKA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: JM705_ORYSJ
Sequence: MRPSPPPAAPAAEPVPPWLRSLPVAPEFRPTAAEFADPVSYILKIEPAAAPYGICKVVPPLPPPPKKATFSNLSRSFAALHPDDRSPSFPTRHQQVGLCPRRTRPGLKPVWRSSHRYTLPQFESKAGATRKSLLAGLNFPASRQLTPLDHEVLFWRASADRPIVVEYGSDMSGSGFSPCAAQPQPPPQQQPTARAAAHLGETAWNMRGVARSPGSLLRFMPEDVPGVTTPMLYVGMMFSWFAWHVEDHDLHSLNYMHLGAAKTWYGVPRDAALAFEDVVREHGYGGEVNPLETFATLGQKTTVMSPEVLVESGIPCCRLVQNAGEFVVTFPGSYHCGFSHGFNCGEASNIATPEWLRIAKEAAIRRASINRPPMVSHYQLLYDLALSMRFREPSNGEMETRSSRIKEKKKCEGEQLVKKMFIQNVIEDNELLSHLLNDGSSCIILPANAHDGPGLSTLRSTDQSNMNSRISHNLCSREEAPEASGCLSPNRNGDTRNCISSDTHNMEGDKGDIMSATGLLDQGLLSCVTCGILSFSCVAVLKPRDSTARYLMSADSNSINNQLSISGGSILADAPTNERNGVISRPYSEHCCNEIMADDAEIDKNSALDLLAFAHGGQPDPEEDPLEKILKIAHGINKSQPNSSNNVGCVGTKLSSSSTERQERPSSQNAHCNGSSVISNGPKGVRTRNKYQLKMVLSEGFQAKDIYSAKEKKVQSEPSSSKGDVKETIDVSGTENDVGCKSTTISVSEHRGSTKNMYSVKEKKVQSKPSSLKGTVKETVDVSGTENDARCKSITISVSEHRGSTPMTNSLAASIVKPDKDSSRMHVFCLEHAIEVEKQLHAIGGSNIMLICRPEYPKIEAEARLLGEEMGLVYDWKGIHFKEANMEDRQKIQEVLRDEEAIPTSSDWAVKLGINLYYSANLAKSPLYNKQMPYNRVIYRAFGCDSPNDSPVMFNTCERKQSHQKKIVVAGRWCGKVWMSKQVHPYLAHRVESQEAEEADRICSYHFDEKHKAEPVGNSSRVEASKRKSSSLTDVTESSNRRGEIPGEETNTKRPKHSQENNLRALETAAEVVVPSPAGTGLRVSSRIANRANKLKSKMEKEDVPSSRPKSNIKEKSSHASGQKSNVQEANANSASHLRAMPPKQKAEAEAKKQIRTPKPPKQAVEYSCDIEGCSMSFRTKRDLSLHKSDICPVKGCGKKFFSHKYLLQHRKVHTDDRPLTCPWKGCNMAFKWPWARTEHLRVHTGDRPYVCHEPGCAQTFRFVSDFSRHKRKTGHSVKKKKKAKS
What is the function of this protein?
Histone demethylase that demethylates 'Lys-27' (H3K27me) of histone H3 with a specific activity for H3K27me3 and H3K27me2.  No activity on H3K4me3, H3K9me3, H3K27me1 and H3K36me3.  Involved in biotic stress response.  May demethylate H3K27me3-marked defense-related genes and increase their basal and induced expression levels during pathogen infection.
What are the official names of this protein?
Lysine-specific demethylase JMJ705, Jumonji domain-containing protein 705, Lysine-specific histone demethylase JMJ705, Protein JUMONJI 705, [histone H3]-trimethyl-L-lysine(27) demethylase JMJ705.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRUA_PELUB
Sequence: MFRYQVLIEYIGTNFVGWQIQSKGKSIQKEIQVKLSKFLKEKVVLIGSGRTDAGVHAIEQSAHFDCKKEIQNLDKLLKSINHFINDKGISVLAIKKRSLKFHARHSAKQRIYKYIIFNRLSKPSLEKERGWHIIKKLDIELMKKGSKKLLGTKDFSTFRASSCNAKSPIKTMKSVNIKSKDGRIEIQFKSQSFLQQQVRSMVGSLKYLAENKWDLKKFEFVIKSKKRILCAPPAPAEGLFLEKVIY
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: CNEPB_DANRE
Sequence: MLKTRQCLLGVRTFHGVTSRIWSFFLYILRKHIRTIIQYQTVRYDILSLSPISRNRLNNVKRKILVLDLDETLIHSHHDGVLRPTVRPGTPPDFILKVVIDKHPVRFFVHKRPHVDFFLEVVSQWYELVVFTASMEIYGSAVADKLDNNKAILKRRYYRQHCTLDSGSYIKDLSVVHDDLSSVVILDNSPGAYRSHPDNAIPIKSWFSDPSDTALLNLLPMLDALRFPADVRSVLSRNLHQHRLW
What is the function of this protein?
Serine/threonine protein phosphatase that may dephosphorylate and activate lipins.  Lipins are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels.  May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics.  May also indirectly regulate the production of lipid droplets and triacylglycerol.  May antagonize BMP signaling (By similarity).
What are the official names of this protein?
CTD nuclear envelope phosphatase 1B, Dullard-like protein, Serine/threonine-protein phosphatase dullard-B.
What is the protein family that this protein belongs to?
Belongs to the dullard family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein.
Protein: NAA50_MOUSE
Sequence: MKGSRIELGDVTPHNIKQLKRLNQVIFPVSYNDKFYKDVLEVGELAKLAYFNDIAVGAVCCRVDHSQNQKRLYIMTLGCLAPYRRLGIGTKMLNHVLNICEKDGTFDNIYLHVQISNESAIDFYRKFGFEIIETKKNYYKRIEPADAHVLQKNLKVPSGQNAETQKTDN
What is the function of this protein?
N-alpha-acetyltransferase that acetylates the N-terminus of proteins that retain their initiating methionine (By similarity).  Has a broad substrate specificity: able to acetylate the initiator methionine of most peptides, except for those with a proline in second position (By similarity).  Also displays N-epsilon-acetyltransferase activity by mediating acetylation of the side chain of specific lysines on proteins (By similarity).  Autoacetylates in vivo (By similarity).  The relevance of N-epsilon-acetyltransferase activity is however unclear: able to acetylate H4 in vitro, but this result has not been confirmed in vivo (By similarity).  Component of N-alpha-acetyltransferase complexes containing NAA10 and NAA15, which has N-alpha-acetyltransferase activity (By similarity).  Does not influence the acetyltransferase activity of NAA10 (By similarity).  However, it negatively regulates the N-alpha-acetyltransferase activity of the N-terminal acetyltransferase A complex (also called the NatA complex) (By similarity).  The multiprotein complexes probably constitute the major contributor for N-terminal acetylation at the ribosome exit tunnel, with NAA10 acetylating all amino termini that are devoid of methionine and NAA50 acetylating other peptides (By similarity).  Required for sister chromatid cohesion during mitosis by promoting binding of CDCA5/sororin to cohesin: may act by counteracting the function of NAA10 (By similarity).
What are the official names of this protein?
N-alpha-acetyltransferase 50, N-acetyltransferase NAT13, N-epsilon-acetyltransferase 50, NatE catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. GNAT subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes to the cytoplasm in interphase cells.
Protein: MURB_BURP6
Sequence: MSRPDSAVSLLPDYSLRAHNTFGFDARARVAARIGSPGQFASLARDPRVAGLDRLVLGGGSNVVFTRDFDGLVLLDEIRSRALVREDDGAWYVEAGGGENWHAFVEWTLAEGMPGLENLALIPGTVGAAPIQNIGAYGLEMKEHFASLRAVDLATGELVEFDAARCAFGYRDSFFKRDGRGRFAIVAVTFRLPKAWTPRIGYADVARELAARGIDARAARARDVFDAVVAIRRAKLPDPLALGNAGSFFKNPVIDAQAFAALRAREPDIVSYPQPDGRVKLAAGWLIDRCGWKGRALGAAAVHERQALVLVNLGGASGADVLALAHAIRRDVLGRFGVELEMEPVCL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIS_ECO8A
Sequence: MLAFCRSSLKSKKYFIILLALAAIAGLGTHAAWSSNGLPRIDNKTLARLAQQHPVVVLFRHAERCDRSTNQCLSDKTGITVKGTQDARELGNAFSADIPDFDLYSSNTVRTIQSATWFSAGKKLTVDKRLLQCGNEIYSAIKDLQSKAPDKNIVIFTHNHCLTYIAKNKRDATFKPDYLDGLVMHVEKGKVYLDGEFVNH
What is the function of this protein?
Catalyzes the dephosphorylation of heptose(II) of the outer membrane lipopolysaccharide core.
What are the official names of this protein?
Lipopolysaccharide core heptose(II)-phosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. Ais subfamily.
What are the subcellular locations of this protein?
Periplasm.