PharMolix/UniProtQA huggingface dataset:
Protein: ALCJ_ASPOR
Sequence: MAMDKKGDLEWMPPRPEPVHWRNRQRSLAYSVTLTLVALFFTFALRPEAFPSFLVRKGLHKSPLEQVLTRVPLTDGHNDFAIWTRAFYQNHIYRANFTDHDELYGQVDFPRLRKGRLGAQFWSVYVECARNPNEPGVQYEIVRDTFQQIDLVHRMINHFPDFLVPASSVADVHHNFYHSPGRISSLLGIEGLHQIGGSASVLRMYHELGVRYASLTHTCHNEYADSEAPEEPRHGGLSTAGEAIVAEMNRMGMIVDLSHTSLATQRAVFNVTRAPVMYSHSSAYALCPHSRNVPDDLLQMLKENDGIVMISLYPEYTNCQDADAASLADVADHIQYVGNLIGYRHVGLGSDFDGMSHGPKGLEDVSKYPDLIQELLDRGVSVDDLVGVTGGNVLRVLGDVEHVARSLADTLPLEDDVKPFFE
What is the function of this protein?
Dipeptidase; part of the gene cluster that mediates the biosynthesis of aspirochlorine (or antibiotic A30641), an unusual halogenated spiro compound with distinctive antifungal properties due to selective inhibition of protein biosynthesis, and which is also active against bacteria, viruses, and murine tumor cells (PubMed:25302411).  The non-ribosomal peptide synthetase (NRPS) aclP is responsible the formation of the diketopiperazine (DKP) core from the condensation of 2 phenylalanine residues (PubMed:25302411).  One Phe residue is tailored into chlorotyrosine by hydroxylation and chlorination, whereas the second Phe undergoes an unprecedented C-C bond cleavage to be converted into glycine (PubMed:25302411).  After formation of the DKP, sulfur is incorporated into the DKP by conjugation with glutathione by aclG, followed by its stepwise degradation to the thiol by aclI, aclJ and aclK, and the dithiol oxidation by aclT (PubMed:25302411).  In addition, oxygenases (aclB, aclC, aclL and aclO) and O-methyltransferases (aclM and aclU) act as tailoring enzymes to produce the intermediate dechloroaspirochlorine (PubMed:25302411).  Ultimately, chlorination of dechloroaspirochlorine by the halogenase aclH is the last step in the aspirochlorine pathway (PubMed:25302411).
What are the official names of this protein?
Dipeptidase aclJ, Aspirochlorine biosynthesis protein J.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PAB2_SCHPO
Sequence: MSDQDALDTQEKELLEMKERVAEMEAEAAKLRAMQEQLDNETEALRNDKESIDAQSVYVGNVDYSVTPEELQSHFASCGSVNRVTILCDKFTGHPKGFAYIEFSEPSLVPNALLLNGSMLHERPLKVTPKRTNVPGMSRGRGRGRGRGRGRGRGGYRGRARGFAPY
What are the official names of this protein?
Polyadenylate-binding protein 2, PABP-2, Poly(A)-binding protein 2, Poly(A)-binding protein II, PABII.
What are the subcellular locations of this protein?
Nucleus.
Protein: YDJC_GEOSE
Sequence: MPRYCIVNADDFGYSKGVNYGILEAFQNGVVTSATLMANMPAAEHAARLAKDHPELGVGIHFVLTCGRPLADVPSLVNENGEFPRRGEALVGARRGDIERELCAQLERFFSFGLTPTHIDSHHHVHEHPNVFPVVEQLAERYRLPIRPVRTARPHRLPTVDVFFPDFYGDGLTKDRFISLIDRIGDGQTAEVMCHPAYIDVPLASGSSYCQQRVEELAVLTDPTLVAEMAERGVQLITYREFYKL
What is the function of this protein?
Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides.
What are the official names of this protein?
Carbohydrate deacetylase.
What is the protein family that this protein belongs to?
Belongs to the YdjC deacetylase family.
Protein: RHLB_SHISS
Sequence: MSKTHLTEQKFSDFALHPKVVEALEKKGFHNCTPIQALALPLTLAGRDVAGQAQTGTGKTMAFLTSTFHYLLSHPAIADRKVNQPRALIMAPTRELAVQIHADAEPLAEATGLKLGLAYGGDGYDKQLKVLESGVDILIGTTGRLIDYAKQNHINLGAIQVVVLDEADRMYDLGFIKDIRWLFRRMPPANQRLNMLFSATLSYRVRELAFEQMNNAEYIEVEPEQKTGHRIKEELFYPSNEEKMRLLQTLIEEEWPDRAIIFANTKHRCEEIWGHLAADGHRVGLLTGDVAQKKRLRILDEFTRGDLDILVATDVAARGLHIPAVTHVFNYDLPDDCEDYVHRIGRTGRAGASGHSISLACEEYALNLPAIETYIGHSIPVSKYNPDALMTDLPKPLRLTRPRTGNGPRRTGAPRNRRRSG
What is the function of this protein?
DEAD-box RNA helicase involved in RNA degradation.  Has RNA-dependent ATPase activity and unwinds double-stranded RNA.
What are the official names of this protein?
ATP-dependent RNA helicase RhlB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. RhlB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SC5A7_DROME
Sequence: MINIAGVVSIVLFYLLILVVGIWAGRKKQSGNDSEEEVMLAGRSIGLFVGIFTMTATWVGGGYINGTAEAIYTSGLVWCQAPFGYALSLVFGGIFFANPMRKQGYITMLDPLQDSFGERMGGLLFLPALCGEVFWAAGILAALGATLSVIIDMDHRTSVILSSCIAIFYTLFGGLYSVAYTDVIQLFCIFIGLWMCIPFAWSNEHVGSLSDLEVDWIGHVEPKKHWLYIDYGLLLVFGGIPWQVYFQRVLSSKTAGRAQLLSYVAAAGCILMAIPPVLIGAIAKATPWNETDYKGPYPLTVDETSMILPMVLQYLTPDFVSFFGLGAVSAAVMSSADSSVLSAASMFARNVYKLIFRQKASEMEIIWVMRVAIIVVGILATIMALTIPSIYGLWSMCSDLVYVILFPQLLMVVHFKKHCNTYGSLSAYIVALAIRLSGGEAILGLAPLIKYPGYDEETKEQMFPFRTMAMLLSLVTLISVSWWTKMMFESGKLPPSYDYFRCVVNIPEDVQRVGDPSESGEQLSVMAGPLARSYGAATMAGKDERNGRINPALESDDDLPVAEARRINQETAQAQVKKMLDNATGVKPSGGGGGHLQSQSGMAMPTAEQDNTAF
What is the function of this protein?
Imports choline from the extracellular space to the neuron with high affinity.  Rate-limiting step in acetylcholine synthesis.  Sodium ion and chloride ion dependent (By similarity).
What are the official names of this protein?
High-affinity choline transporter 1.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SEC1B_ORYSJ
Sequence: MSMSGSDFGAPCDDPKIFRNICRDRILKDLLQPDKDKETKSSWKVLIMDKFTVRIMAYACKMAEITDAGISLVEDLFKRREPMPSMDAIYFLQPLKENVIMLLSDMSGRCPLYRKAYIFFSSPIPKELVSYIKNDSSVIPRIGALREMNLEFFAIDMQGFTTDHDMAFTDLYSAQHNSKKFNDTISTMATRIATTFASLKEFPCVRYRAPKGTDPMTTPKFDMVPKWLATAVWDIVSKYKSTIPEFPQKETCELLIVDRPIDQIAPVIHEWTYDAMCHDLLEMDGQKYIYEVSKAGSEPERKEALLEDHDPLWVELRHIHIADASERLYDKMNNFVSKNKAAQLHSRDGGEISTKDLQKIVQALPQYGEQVEKLTLHIEIAGKINKFIREYGLRDIGQVEQDLVFGDAAAKEVISILRSKQDMSPENKLRLLIIYAIVYPEKFEGDKGEKLMQLAKLPHDEMDAINSLRYLVGSDTKKASRPGGFSLKFDAQKKKNAARTERQDGDETWALSRFFPLIEELIEKLSKGALPLNEYPSMSEPSSTEQGSTQSAAATKPAQAQPMSRRSRRTPTWAKSRNSDDSQSSDSSVLRHGSNDFKRLGNRIFVFMIGGATRSELRTVHKLTMKLKREIVLGSSSIDDPPQFISKLKMLTAGGANDV
What is the function of this protein?
Involved in the vesicle trafficking.  Binds syntaxins (By similarity).
What are the official names of this protein?
Probable protein transport Sec1b.
What is the protein family that this protein belongs to?
Belongs to the STXBP/unc-18/SEC1 family.
Protein: Y667_PSELT
Sequence: MNWKEAEEKASRYLRHKGFKILARNYRTRFGEIDIIARYRGYLVFVEVKSGNSFFLPRTRVDLQKIRHIQLAANDYIMNTKDSFKGYRIDVIEVTEKGIEHFEDIQI
What are the official names of this protein?
UPF0102 protein Tlet_0667.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: RS2_JANMA
Sequence: MSVTMREMLEAGVHFGHQTRFWNPKMAPFIFGHRNRIHIVNLEKTMGMYQEAMKYIRQLSSNRGTVLFVGTKRQARETIAAEAQRAGMPYVDQRWLGGMLTNFKTIKTSIKRLKEMEASIEDGSVQKLSKKEALMFEREKIKLEKSIGGIKDMGGIPDAIFVVDVGYHKGAITEAAKLGIPVIGVVDTNHSPEGVTYVIPGNDDSSKAIMLYARGVADAILEGRANATNDLVESIKGGDDFVEVSEQA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: KDSB_BURM7
Sequence: MTSPLPFVAVVPARLASTRLPNKPLADLGGKPMVVRVAERAREAGAQQVLVASDAQRVLDAVREHGFDAVLTRADHPSGTDRLAEVAAKLGFDDDTIVVNVQGDEPLIDPQLVRDVASHLAAHPSCAIATAAHPIHEAHEVFNPNYVKVVLDAHGVALYFSRAPIPWSRDAYLPHWPNVAAMPAPTCPVYRHIGLYAYRARFLRTYPTLAQAPIEAAEQLEQLRAMWHGERIAVRVTEHAPEAGIDTPADLERVQALFRSRAK
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_PSEAB
Sequence: MPRRRVAAKREVLADPKYGSQILAKFMNHVMESGKKAVAERIVYGALDKVKERGKADPLETFEKALDAIAPLVEVKSRRVGGATYQVPVEVRPSRRNALAMRWLVDFARKRGEKSMALRLAGELLDAAEGKGAAVKKREDVHRMAEANKAFSHYRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: CTAA_SYMTH
Sequence: MKALRAVSLANTAVMLLAVLWGAWVTSSDSGDGCGASWPLCKGTFMPDWDYAAIVEFGHRVVSALAGLLSVAVLVWVARVRPSETRLKRLAFGTFFFVVLQGGLGAAAVLRPQPDLVMALHFGFSLLCFTFALLVTVALGQGERAAFQRPDVSAQPVAPGLRTQIWGLAVYTYLVVYLGAYVRHLGASMACTGWPLCNGELIPPLYGPVGANFAHRLGAALAVVLVLRLWWTARRLTERDDLRRGAAWALALMAAQVASGALFPLGYLNLLTQLLHTGLITGFWGVLSYLCYLTLPVGRETVAVSA
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VG20_BPMD2
Sequence: MSLLDTGARYQPVLVYPEELVIDADGNKKTQPSKTPIQAIARFQVANQSGTSARRAEQDNGGFTTEKVYRMRFPRSFTKEHGILGAQTQIEWKGQRWALFGDATEYDSSPALARVDYTIKRF
What are the official names of this protein?
Gene 20 protein, Gp20.
Protein: Y2349_CORGL
Sequence: MPVRVIVDSSACLPTHVAEDLDITVINLHVMNNGEERSTSGLSSLELAASYARQLERGGDDGVLALHISKELSSTWSAAVTAAAVFDDDSVRVVDTSSLGMAVGAAAMAAARMAKDGASLQECYDIAVDTLKRSETWIYLHRIDEIWKSGRISTATAMVSTALATRPIMRFNGGRMEIAAKTRTQSKAFAKLVELAQIRADGEPVFIAIGQNEAREAAKQLEELLRNALPEGSSFMSVDIDPTLAVHSGPGAVSVSAVFANQAPELSTGKAGAK
What is the function of this protein?
Binds long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.
What are the official names of this protein?
DegV domain-containing protein Cgl2349/cg2579.
Protein: PAP_EHV1V
Sequence: MALPRAMRPGGSHPNNFLFNTLPVIDNPVERQRAMAVFERESLRDAFEMLTPIAPSLKNAFLIFNEDGLLIHTSVGGEQVYIPIQTNNMESYSWKKAPPAVFLANVDGRRGLLDAFKAKTQTNVSKVVFEIENYSPSRILTQTVFSARDQTEEDTEMGSDAEGATQTVSSRLVKHEFNNYALMLPTRQPDVSMSLSKAQLNKILGVCKQAGDPITFQCLFDDTLQVRSGDRQVVFSVDYQHADNCGVESSSSLLEKMPMKTKKSAPEPIRGISGRRLFTLVLDEDTNFKQLIQKLKLKNAGAVLNFFLDPDSIPMIGLSTKQPFSVMMFFMCSYPTQPCQVGFSPAAFSSTPMGAGVKRRASEEEESDQPPKKLFPDGKLFKSNFVLLMDKTGAKIPCPEQPMHF
What is the function of this protein?
Plays an essential role in viral DNA replication by acting as the polymerase accessory subunit.  Associates with the viral polymerase to increase its processivity and forms high-affinity direct interactions with DNA.  Facilitates the origin-binding protein loading onto DNA thus increasing its ability to assemble into a functional complex capable of unwinding duplex DNA (By similarity).
What are the official names of this protein?
DNA polymerase processivity factor, Polymerase accessory protein, PAP.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae DNA polymerase processivity factor family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: NUDJ_ECODH
Sequence: MFKPHVTVACVVHAEGKFLVVEETINGKALWNQPAGHLEADETLVEAAARELWEETGISAQPQHFIRMHQWIAPDKTPFLRFLFAIELEQICPTQPHDSDIDCCRWVSAEEILQASNLRSPLVAESIRCYQSGQRYPLEMIGDFNWPFTKGVI
What are the official names of this protein?
Phosphatase NudJ.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudJ subfamily.
Protein: LOVG_AEDAE
Sequence: MMANETAAKSTKSSPTPAVEPESKLKILALHGYRQNGDGFKSKLGSFRKFIGKHAELVFVTAPHIAPPLPDSEAGTEPDPAQRSWWFNKDDGTFKGTNKNGPAIGFEDSLKLVEKVWKQEQCCGLLGFSQGACFVGLLCDLSARGMTSIKPEFAVLSSGFRSGSLVHLNCYETKVQIPSLHIYGEADEIIPKEMSMALADTFTDPQILTHPGGHFLPAQASQKQTYVEFFRERLQFHLEAQEIENATAANSILVDDSGPAGNGVHDDDDDDDDSD
What are the official names of this protein?
Esterase AAEL000016.
What is the protein family that this protein belongs to?
Belongs to the LovG family.
Protein: PA2A4_NAJSG
Sequence: SNRPMPLNIYQFKNMIQCTVPSRSWWDFADYGCYCGRGGSGTPVDDLDRCCQVHDNCYNQAQEITGCRPKWKTYTYECSQGTLTCKGRNNACAATVCDCDRLAAICFAGAPYNDNNYNIDLKARCQ
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that exhibits strong anticoagulant activity, which is not due to the catalytic activity.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Acidic phospholipase A2 4, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y3998_PSEAE
Sequence: MTDTPDVQPPKIEFPCERYPIKVIGDAGEGFSDLVVEIIQRHAPDLDVETLVVRDSSKGRFLSVQVLITATDVDQLQAIHNDLRATGRVHMVL
What are the official names of this protein?
UPF0250 protein PA3998.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.
Protein: TGM4_MOUSE
Sequence: MDSRNVLIIYAVNVERKLNAAAHHTSEYQTKKLVLRRGQIFTLKVILNRPLQPQDELKVTFTSGQRDPPYMVELDPVTSYRSKGWQVKIAKQSGVEVILNVISAADAVVGRYKMRVNEYKAGVFYLLFNPWCSDDSVFMASEEERAEYILNDTGYMYMGFAKQIKEKPWTFGQFEKHILSCCFNLLFQLENNEMQNPVLVSRAICTMMCAANGGVLMGNWTGDYADGTAPYVWTSSVPILQQHYVTRMPVRYGQCWVFSGILTTALRAVGIPARSVTNFESAHDTEKNLTVDIYLDESGKTIPHLTKDSVWNFHVWTDAWMKRQDLPHGYDGWQVLDSTPQEISDGGFRTGPSPLTAIRQGLIQMKYDTTFVFTEVNGDKFIWLVKQNQEREKNILIAVETASLGKKISTKMVGENRREDITLQYRFPEGSPEERKVMAKASGKPSDDKLNSRTLNNSLQISVLQNSLELGAPIYLTITLKRKTATPQNVNISCSLNLQTYTGNKKTNLGVIQKTVQIHGQESRVFLTMDASYYIYKLGMVDDEMVIGGFIIAEIVDSGERVATDTTLCFLYSAFSVEMPSTGKVKQPLVITSKFTNTLPIPLTNIKFSVESLGLANMKSWEQETVPPGKTITFQMECTPVKAGPQKFIVKFISRQVKEVHAEKVVLISK
What is the function of this protein?
Associated with the mammalian reproductive process.  Plays an important role in the formation of the seminal coagulum through the cross-linking of specific proteins present in the seminal plasma.  Transglutaminase is also required to stabilize the copulatory plug.
What are the official names of this protein?
Protein-glutamine gamma-glutamyltransferase 4, Experimental autoimmune prostatitis antigen 1, Transglutaminase-4, TGase-4.
What is the protein family that this protein belongs to?
Belongs to the transglutaminase superfamily. Transglutaminase family.
What are the subcellular locations of this protein?
Secreted.
Protein: SNUT2_MOUSE
Sequence: MSSRSKRQSHGSTRGKRESESRGSSGRIKKERDREKEPEAASSRGSPVRVKREAEPAAREVPAPALPVVRVKREREADEDSEPEREVRAKNGRVDSEDRRSRHCPYLDTINRSVLDFDFEKLCSISLSHINAYACLVCGKYFQGRGLKSHAYIHSVQFSHHVFLNLHTLKFYCLPDNYEIIDSSLEDITYVLKPTFTKQQIANLDKQAKLSRAYDGTTYLPGIVGLNNIKANDYANAVLQALSNVPPLRNYFLEEDNYKNIKRPPGDIMFLLVQRFGELMRKLWNPRNFKAHVSPHEMLQAVVLCSKKTFQITKQGDGVDFLSWFLNALHSALGGTKKKKKTIVNDVFQGSMRIFTKKLPHPDLPAEEKEQLLHNDEYQETMVESTFMYLTLDLPTAPLYKDEKEQLIIPQVPLFNILAKFNGITEKEYKTYKENFLKRFQLTKLPPYLIFCIKRFTKNNFFVEKNPTIVNFPITNVDLREYLSEEVQAVHKNTTYDLIANIVHDGKPSEGSYRIHVLHHGTGKWYELQDLQVTDILPQMITLSEAYIQIWKRRDNDETNQQGA
What is the function of this protein?
Plays a role in pre-mRNA splicing as a component of the U4/U6-U5 tri-snRNP, one of the building blocks of the precatalytic spliceosome.  Regulates AURKB mRNA levels, and thereby plays a role in cytokinesis and in the spindle checkpoint.  Does not have ubiquitin-specific peptidase activity.
What are the official names of this protein?
U4/U6.U5 tri-snRNP-associated protein 2, Inactive ubiquitin-specific peptidase 39.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LCL2_PYRTT
Sequence: MSILLTTILLTLLTTPTLAQFGFFDQMFGGNGGQQQQQGHHHHHEQQEAQNVRSDSSWYQSQYEGAQCTHYLCPGTLSCVHFPHHCPCAWEAVEDKVELGDGIAICGSKGGWVAGEFEKKVEMARKGLL
What is the function of this protein?
Probable component of the endoplasmic reticulum-associated degradation (ERAD) pathway.
What are the official names of this protein?
Long chronological lifespan protein 2.
What is the protein family that this protein belongs to?
Belongs to the LCL2 family.
Protein: AR2BP_MOUSE
Sequence: MDALEEESFALSFSSASDAEFDAVVGCLEDIIMDDEFQLLQRNFMDKYYQEFEDTEENKLTYTPIFNEYISLVEKYIEEQLLERIPGFNMAAFTTTLQHHKDEVAGDIFDMLLTFTDFLAFKEMFLDYRAEKEGRGLDLSSGLVVTSLCKSSSTPASQNNLRH
What is the function of this protein?
Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3.  May play a role as an effector of ARL2 (By similarity).
What are the official names of this protein?
ADP-ribosylation factor-like protein 2-binding protein, ARF-like 2-binding protein, Binder of ARF2 protein 1.
What is the protein family that this protein belongs to?
Belongs to the ARL2BP family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Cytoplasm, cytoskeleton, cilium basal body. Note=Detected in the midbody matrix. Not detected in the Golgi, nucleus and on the mitotic spindle. Centrosome-associated throughout the cell cycle. Not detected to interphase microtubules (By similarity). The complex formed with ARL2BP, ARL2 and SLC25A4 is expressed in mitochondria. In retina photoreceptor cells, localized in the distal connecting cilia, basal body, ciliary-associated centriole, and ciliary rootlet. Interaction with ARL2 may be required for cilia basal body localization (By similarity).
Protein: RL1_BUCAI
Sequence: MNKKTKRMKKIKEHINFAKLHHIDETIDLLKKSSTVKFNESIDIAINLGINSKKSDQNIRSSTVLPNGIGRSIRVAVFTQGDNIAIAKDAGAELIGMEDLSEKIKKEGVDFDVVIATPDAMKIVTQLGQILGPRNLMPNTKLGTITTNIAEAIKNAKTGQVRYRNDKNGIIHATIGRINFHKNEIKENLNVFLESIKKAKPPQSKGIYIKKIVLSTTMGVGLMVDQSTLSL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: PYRH_BURCH
Sequence: MSNAYKRVLLKLSGEALMGDDAFGINRATIERMVADIAEVVRLGTQLAVVIGGGNIFRGVAGGAAGMDRATADYMGMLATMMNALALQDAMRHAGIEARVQSALRMDQVVEPYIRPRAIRQLEEGRVVIFAAGTGNPFFTTDTAAALRGSEVGAEVVLKATKVDGVYSADPKKDPSATRYTTISFDEAISRNLQVMDATAFALCRDQKLPIRVFSINKPGALKRIVLGEDEGTLVHV
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_AFIC5
Sequence: MLPDAKLDILLARHAALEAELLGQLNAEAYVRATRELAELTPVVDAVKAYRAGASELSDLDAMIDDPTTDAEMRAMAESERPVLQERQENLEQQIRIALLPKDAMDERNVVLEVRAGTGGDEASLFAGDLFRMYERFAALQGWKVEVISASEGTVGGYKEIVAQVQGRGAFAKLKFESGVHRVQRVPDTEASGRIHTSAATVAVLPEAEEIDIDIKDTDLRIETMRAQGAGGQHVNKTESAIRITHIPTGIVVMMQDSRSQHKNRASAMNILRSRILDAERQRAASERSADRRGQVGSGDRSERVRTYNFPQGRVTDHRINLTLYKLPQVIAGEALNELIDALTTEHQAALLATETSA
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NHAA_ANADE
Sequence: MNRADARRARPAPEGRPMSGPGPLPVRLDPPVDPARDHVLGEPGADLTLVEYGSYACPHCHVAHEVVAELRDRLGDRLRYVFRQRPIRAEAARPAAELAEAAGLDGERFWHAHDLLMRRGPSFAAGELDAIARELGLPPRERGAGPWEGAAARVREDVESARRSGVHLTPTFFINGRRYEGPWDAAALSEALLGSLGHRLHAATLDFARWAPSTGLLLVVATAIAVAIANSSAGAAFTAAWQAPLGLSLGGRGFALPLVQWVNDGLLTLFFLVVGLEIKRELTVGRLASWRAAALPMAAAIGGMVAPAALYLLVIPAGPLAGGWGTTISTDTAFAVAILVLLGDRVPVDLRVFLTAAVIVDDLVAIAVVALFYSGAISLPWLLAAAAVTALLAGLNRAAISAAPPYVALGALLWACLHAAGLHPTLAGVILAVVTPTRPPPDLRALTGQAQAVLEAELRRAREGVLRHGPSEPALRALDAIHDRIESPASKLLRTLDPWASYAVLPVFALANAGVAWVPGALDGRGRLVAAIVLGLVAGKPLGMFLAARLAVRAGLAVKPAAYAWRQLAGAGALAGIGFTMSLFIAGQAFPDPADFRAAKIAIFAASLLAGVLGALVLWPRRSPAAEAEALPAPEGSEVDAAGT
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ART10_YEAST
Sequence: MAPKISISLNPPYNGEFYSSNDQMSGIVSLQLTKALSIRKISVILKGFSETLTKIDQEYMFQQNGMMMPGQDNKSFHTLMKFEQRVFPPDNVWNALDGSSKPFKVKPGSYNYSFQFDKFPRKPECLKNHTAKTVAFVTRSNARLPPTFNSHWQEFNKIDNLDLYFYSFGKVIYMVQVQLELGKSSSWFKPFHKLIREIETFEFIPEPKDLIIEPDEDDNEELNAFSNNSRGNSMVTNNEFFNSSNLKVPSKDVKVVNGVGYIKSDRNFSQANSILIENGDIRSRPVSSVTSTRQSTRLVNGMKVFPSTYKMGLPDGESNMRIEVRSRDLKQIYRKDYLFRSGSQNFDKVYVVMEGNIASLSKMQITPLKLQLNLLETTTYLSQGIANGNYSSLKLIEIDLNQLKSNKPLLDLNEIRENFDGSMFECELRLKDHPILRKLVFNEEDYRHRGNRLYSFKTCTIKRTFSLQLLIEWGINGIRKQSEVNIDPVQIFCQVREHVEAEALPRYVPPPTYTEMAS
What is the function of this protein?
May regulate endocytosis by recruiting RSP5 ubiquitin ligase activity to specific plasma membrane proteins in response to extracellular stimuli.
What are the official names of this protein?
Arrestin-related trafficking adapter 10.
What is the protein family that this protein belongs to?
Belongs to the ART10 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PVK3_DERCR
Sequence: GSSGMISFPRT
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-3, DerCr-PVK-3.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: DIAA_ECOHS
Sequence: MQERIKACFTESIQTQIAAAEALPDAISRAAMTLVQSLLNGNKILCCGNGTSAANAQHFAASMINRFETERPSLPAIALNTDNVVLTAIANDRLHDEVYAKQVRALGHAGDVLLAISTRGNSRDIVKAVEAAVTRDMTIVALTGYDGGELAGLLGPQDVEIRIPSHRSARIQEMHMLTVNCLCDLIDNTLFPHQDD
What is the function of this protein?
Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein.
What are the official names of this protein?
DnaA initiator-associating protein DiaA.
What is the protein family that this protein belongs to?
Belongs to the SIS family. DiaA subfamily.
Protein: PYRC_PSEU2
Sequence: MSDRLTLLRPDDWHIHLRDGAVLPHTVADVARTFGRAIIMPNLVPPVRNAQQADAYRQRILAARPATSRFEPLMVLYLTDQTTPDDIRTAKASGFVYAAKLYPAGATTNSDSGVTSIDKIFPALEAMADVGMLLLVHGEVTRGEIDVFDREKVFIDEHLRRVVERFPSLKVVFEHITTGEAVQFVNEASANVAATITAHHLLYNRNHMLVGGIRPHFYCLPILKRNTHQTALLDAATSGSGKFFLGTDSAPHAQHAKENACGCAGCYTAYAAIELYAEAFEQRNALDKLEGFASLHGPAFYGLPANQDTITLVRDEWTAPASLPFGELTVIPLRAGETLRWRLEEHA
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.