PharMolix/UniProtQA huggingface dataset:
Protein: CH601_ROSS1
Sequence: MAKQVIFNEQARAALKHGVDTLALAVKTTLGPRGRNVAMGKKWGAPSVTHDGVTVAKEVELKDPFQNMGAQLLKEAASKTNDVAGDGTTTATVLAQAMIDEGLKLVAAGANPMIFKRGLDKGREALVARIKEQSITLKSRDEIRQVATISAQDPEIGELLATIMDKIGHDGVVTIEEGKGTTLEYELVEGMQFDRGYISPYFVTDSSRMEAVIDEPYILITDKKISAVNDLLPILEAVLATGKKDLVIIAEDVDGEALATLVVNKMRGTLNALAVKAPGFGDRRKAMLQDIAILTGGTVISEEVGRKLDSAKVQDLGRARRVKSDKDNTVIVEGFGDKQAIQARIRQLKQQIETTTSDYDREKLQERVAKLSGGVAVIKVGAPTEPALKERKARVEDALNATRAAVEEGIVPGGGIALLNAIPALDNVQTQFEEERMALNILRRALEEPLRQLAINAGEDGSVVVNQVRTLQREHNNPNYGFDVMTGKYVDLMQAGIIDPAKVVRTALENAVSVAGIVLTTDALITDAPEPKKNGARTPSMPEEEF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 1, 60 kDa chaperonin 1, Chaperonin-60 1, Cpn60 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XYNA_SCHCO
Sequence: SGTPSSTGTDGGYYYSWWTDGAGDATYQNNGGGSYTLTWSGNNGNLVGGKGWNPGAASRSISYSGTYQPNGNSYLSVYGWTRSSLIEYYIVESYGSYDPSSAASHKGSVTCNGATYDILSTWRYNAPSIDGTQTFEQFWSVRNPKKAPGGSISGTVDVQCHFDAWKGLGMNLGSEHNYQIVATEGYQSSGTATITVT
What is the function of this protein?
Hydrolyzes xylans into xylobiose and xylose.
What are the official names of this protein?
Endo-1,4-beta-xylanase A, Xylanase A, 1,4-beta-D-xylan xylanohydrolase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 11 (cellulase G) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS10A_CANAL
Sequence: MLIPKEDRKKIHQYLFQEGVVVAKKDFNQPKHDEIDTRNLFVIKALQSLTSKGYVKTQFSWQYYYYTLTDEGVEFLRTELNIPEGILPLTRLKNAPAERPRPSRGGPRRGGYRGRARD
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
40S ribosomal protein S10A.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS10 family.
Protein: MIAA_LEPBP
Sequence: MILPILGGPTGSGKTSLTQVLDPKRFEIVSFDSRQVYRDLPVGTTAPTPEECSTIRHWLIGFLNANESINANQFSLLARNAIADIQSRGKIPFLLGGTGFYLRAFLLGMYPVPTVPKETKDYVFTLPLEEARSQLLAKDPKAMESLSDQDGYRIKRALEVVLTGVLWSDVSKETVGGFWKDNPEVKIVGHWLDWPREILYQRINTRVETIIRGMLEETKEVLSKYGPDCPGLRTLGYNFALAFLNGMIDSNTFIEQLAQSHRNYAKRQITWFKKESFLSPISYDAAVQLYTNIEQR
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: CD226_HUMAN
Sequence: MDYPTLLLALLHVYRALCEEVLWHTSVPFAENMSLECVYPSMGILTQVEWFKIGTQQDSIAIFSPTHGMVIRKPYAERVYFLNSTMASNNMTLFFRNASEDDVGYYSCSLYTYPQGTWQKVIQVVQSDSFEAAVPSNSHIVSEPGKNVTLTCQPQMTWPVQAVRWEKIQPRQIDLLTYCNLVHGRNFTSKFPRQIVSNCSHGRWSVIVIPDVTVSDSGLYRCYLQASAGENETFVMRLTVAEGKTDNQYTLFVAGGTVLLLLFVISITTIIVIFLNRRRRRERRDLFTESWDTQKAPNNYRSPISTSQPTNQSMDDTREDIYVNYPTFSRRPKTRV
What is the function of this protein?
Involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell (PubMed:8673704).  Cell surface receptor for NECTIN2.  Upon ligand binding, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG.  Competes with PVRIG for NECTIN2-binding (PubMed:26755705).
What are the official names of this protein?
CD226 antigen, DNAX accessory molecule 1, DNAM-1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: ATPF_MESH2
Sequence: MVNLNQSLGDLFKGIIPNVYVLGATIVSFLILFLFITYFVYRPLKKYIKKRKDFLQSHIDLTIKSNVEAEKLEKKSQQKLLETKEFCTDLKEKSQIEANKFLEDAKKTAIDNARQLINEGQKVLLEYENEIKSKYYMNVINVAVEICQKYLEKQDKNNKILQQSLIADLEKELKKRENSSKKKDNFGK
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: EFTS_MYCVP
Sequence: MANYTAADVKRLRELTGAGMLDSKNALVEAEGDFDKAVELLRIKGAKDVGKRAERATAEGLVAAKDGALIELNSETDFVAKNGEFQALADQIVAAAAAAKAADVDALKAVKLGDTTVEQAIADLSAKIGEKLELRRATYFDGTTETYLHKRAADLPPAVGVLVEYTGGDTSAAHAVALQIAALKAKYLTREDVPADIVANERRIAEETARNEGKPEQALSKIVEGRVTGFYKDVVLLDQPAVSDNKKSVKALLDEAGVTVTRFVRFEVGQA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TCR_STAES
Sequence: MFSLYKKFKGLFYSVLFWLCILSFFSVLNEMVLNVSLPDIANHFNTTPGITNWVNTAYMLTFSIGTAVYGKLSDYINIKKLLIIGISLSCLGSLIAFIGHNHFFILIFGRLVQGVGSAAFPSLIMVVVARNITRKKQGKAFGFIGSIVALGEGLGPSIGGIIAHYIHWSYLLILPMITIVTIPFLIKVMVPGKSTKNTLDIVGIVLMSISIICFMLFTTNYNWTFLILFTIFFVIFIKHISRVSNPFINPKLGKNIPFMLGLFSGGLIFSIVAGFISMVPYMMKTIYHVNVATIGNSVIFPGTMSVIVFGYFGGFLVDRKGSLFVFILGSLSISISFLTIAFFVEFSMWLTTFMFIFVMGGLSFTKTVISKIVSSSLSEEEVASGMSLLNFTSFLSEGTGIAIVGGLLSLQLINRKLVLEFINYSSGVYSNILVAMAILIILCCLLTIIVFKRSEKQFE
What is the function of this protein?
Resistance to tetracycline by an active tetracycline efflux.  This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells.  This protein functions as a metal-tetracycline/H(+) antiporter.
What are the official names of this protein?
Tetracycline resistance protein.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TPPC2_CAEEL
Sequence: MATKEFYFAIIGHCDQPIFEMDFPVGEKKTKESEGTRHLNHYIGHAALDIVDEHALTTSQMYLKMVDKFNEWYVSAFVTASRIRFIMLHTHRADEGIKQFFQEMYETYIKHAMNPFYEIDDVIESPAFEQKATLYGRKYLS
What is the function of this protein?
May play a role in vesicular transport from endoplasmic reticulum to Golgi.  Required for the systemic spread of the RNAi response.
What are the official names of this protein?
Probable trafficking protein particle complex subunit 2.
What is the protein family that this protein belongs to?
Belongs to the TRAPP small subunits family. Sedlin subfamily.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Endoplasmic reticulum. Golgi apparatus.
Protein: ISPD_DEHM1
Sequence: MFLNEKVGAVIVAAGQSRRMGGQDKIFARLSGKPVLAHTLSVFQQSPEIDDIALVVSEHNLKKAKELVKEYNFSKVIAICSGGELRQDSVSSGLTALCDCGWVLIHDGARPLLDPVSIPEGLEAAKLCGSAVAAVPLKDTVKEISPEGLVEKTLPREKLISVQTPQVFRADIIQKAYRRVGITATDDAQLVEKLKLPVKIFSGAYANIKITTPEDLLMAEILLKKGR
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: BTUB_VIBVY
Sequence: MQKSLLAIAMASLLTPISYLHAQEVQTNDTVVVTANRFEQVESSVLASISVVTKAEIEQLNVTTALDILKTLPGVEVNSQGGKGQISSIFLRGTSSKHTLVLVDGVKINSATAGGASLGLIPAFAIEQIEVVRGPRAAIYGSDAIGGVIHIKTIPANRQTKHDANLGYGNDDHSSLAWRSSGQLNDSTQASFVFSDEKSDGYRVNEVAPSGDSHGYQSQTLFGSLRHEIDDAWSVQFNGYQLSSDVEYANQFSGVKNESNTDFYSIAGSLNFHKDNYSSQLMVSRSDNESWDGVASGMVAKTALFSSRNSVSWLNHWVVVPALTLAAGVDYDQENARQGGANATNYSKTEKDNKAAYVTAHFSKNIVTAEASIRSDDDSAFGKHNTWNLGLGIAPSDYVEFIASTGTGFKAPTFNDLYWPSSGNPNLKPETSKSSEVGIRSYLPFVQIDISAYRNEIEDMIDWAPTGPGGAWTPSNIDNAKIEGIEIEALFETGVIEHRVSAEWKDPRDKSDDSFLIRRARENFSWVSTYSADRFGFSAVANYVGDRKDSTGKTMDAYTLLDISANYKMTEALTLGARVGNLFDKEYQTAHSSGGKYYVGEGRNWFATVNYRF
What is the function of this protein?
Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space.  It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB.
What are the official names of this protein?
Vitamin B12 transporter BtuB, Cobalamin receptor, Outer membrane cobalamin translocator.
What is the protein family that this protein belongs to?
Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: UXUA_BRUSU
Sequence: MRQAWRWFGPEAGVPLDAVRQAGATDIVSALHEVPIGQEWTSAQIVERKNLIESTPTGRHPLTWSVVESIPVSDDIKRSGKAARHDIGAWIASMEALARNDIKVICYNFMPVVDWCRTDLDYITSTGATAMRFDQDRFAAFDLHILQRKGAEKDYSEEDRIAARAIFEAMDETEIEQLIVNIASALPGSTTEPLTIPAFREKLETYASIDAAHLRRNLVEFLEAVTPVADSLGVKLTLHPDDPPRSLFGLPRIASTEADYAAIFAAVPAQSNGMCFCTGSLGVRADNDLPAIARRFASRIHFSHLRATTREGDGRTFHEAAHLEGDVDMVGILRILLEEDRKRDAGQTIIFRSDHGHRMMDDLEKKVTPGYPVIGRMRGLAELRGIITALDACALEYDPNV
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.
What are the official names of this protein?
Mannonate dehydratase, D-mannonate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the mannonate dehydratase family.
Protein: ARGC_PROM5
Sequence: MNVAIVGATGYGGIQSVNLLKDNKNYKISYLGGYKTSGTKWSDNFPFIKLDSNNLIEKISIDRIADKADVALLCLPNGISSTLTRGLLEKGVKVIDLSADYRYKSLEQWKRIYSNEAAKYKRDDDDLCKEAVYGLPEINNKDISKARLIACPGCYPTSALIPLIPFLSQGIIDNEGIIIDSKSGTSGGGRESSQKLLFSECGDGLSAYGLINHRHTSEIEQIASFISGNDIELLFTPHLLPMIRGMHSTIYGRLRDPGLTSSDCRIILENFYRNYSNIRVLPVDIYPSTKWVKNTNEIHLSVKVDNRNGRIILLSVIDNLLKGQTGQAIQNLNLISGLPLNNGLEMINHYP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVD_STAEQ
Sequence: MRSDMIKKGDHQAPARSLLHATGALKQPTDMNKPFVAICNSYIDIVPGHVHLRELADIAKEAIREAGAIPFEFNTIGVDDGIAMGHIGMRYSLPSREIIADAAETVINAHWFDGVFYIPNCDKITPGMLLAAVRTNVPAIFCSGGPMKAGLSAQGKALTLSSMFEAVGAFKEGTISKEAFLDMEQNACPTCGSCAGMFTANSMNCLMEVLGLALPYNGTALAVSDQRREMIRQAAFRLVENIKNDIKPRDIITQDAIDDAFALDMAMGGSTNTVLHTLAIANEAGIDYDLERINEIAKKTPYLSKIAPSSSYSMHDVHEAGGVPAIINELMKKDGTLHPDRLTVTGKTLRENNEGKNIKNFDVIHPLENPYDKQGGLSVLFGNLAPKGAVIKVGGVDPSIKVFTGKAICFNSHDEAVEAIDNHTVREGHVVVIRYEGPKGGPGMPEMLAPTSSIVGRGLGKDVALITDGRFSGATRGIAVGHISPEAASGGPIGLIRDGDKITIDLINRTLNVNQSEEELYRRKNQLEPFRAKVKTGYLARYTSLVTSANTGGIMQVPENLI
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: FABI_ECOLI
Sequence: MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMNELELK
What is the function of this protein?
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).  Involved in the elongation cycle of fatty acid which are used in the lipid metabolism and in the biotin biosynthesis.
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI, ENR, NADH-dependent enoyl-ACP reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Protein: SELA_ECO55
Sequence: MTTETRSLYSQLPAIDRLLRDSSFLSLRDTYGHTRVVELLRQMLDEAREVIRGSQTLPAWCENWAQEVDARLTKEAQSALRPVINLTGTVLHTNLGRALQAEAAVEAVAQAMRSPVTLEYDLDDAGRGHRDRALAQLLCRITGAEDACIVNNNAAAVLLMLAATASGKEVVVSRGELVEIGGAFRIPDVMRQAGCTLHEVGTTNRTHANDYRQAVNENTALLMKVHTSNYSIQGFTKAIDEAELVALGKELDVPVVTDLGSGSLVDLSQYGLPKEPMPQELIAAGVSLVSFSGDKLLGGPQAGIIVGKKEMIARLQSHPLKRALRADKMTLAALEATLRLYLHPEALSEKLPTLRLLTRSAEVIQIQAQRLQAPLAAHYGAEFAVQVMPCLSQIGSGSLPVDRLPSAALTFTPHDGRGSHLESLAARWRELPVPVIGRIYDGRLWLDLRCLEDEQRFLEMLLK
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RADB_ARCFU
Sequence: MQRMLIPTGSKCIDSLLGGGVETGTVTQIYGHGGTGKTTLCLMLAKNAAEQFKVAYIDTEGLSGERVRQIFGDERLFSNVFVYEVYRFRQQGVAIQEAEKLCRSEKVKLVIVDCFTSLYRSELEDDRKQIKIKRELTSQLTFLLGMARKYDVAVVITNQMFTDVGSGVDRPLGGPSLEHLSKVIIALERSNELRKATLIKHRWMKEGKSCFYRITDRGIEP
What is the function of this protein?
Involved in DNA repair and in homologous recombination.  May regulate the cleavage reactions of the branch-structured DNA.  Has a very weak ATPase activity that is not stimulated by DNA.  Binds DNA but does not promote DNA strands exchange (By similarity).
What are the official names of this protein?
DNA repair and recombination protein RadB.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RecA-like protein family. RadB subfamily.
Protein: PROA_BARHE
Sequence: MKDMGRKARRAATVLAVMSSEQKNKALEMIALSLEAHSDEILRANHQDLLNATQNNLTVAMVDRLKLNEVRLCTIIDSVRQVACLPDPVGQVMDEWTRPNGLHISRVRTPLGVIGIIYESRPNVTIDASTLCLKAGNAAILRGGSDSFHSAHALHCALVKGLKKAGFPKDAIQMVATKDRGAVGEMLKGLDGAIDVIVPRGGKNLVARIQVDARVPIFAHLEGLCHIYIDQSADLDMARNIVLNAKLRRTGICSAVETVLIDRQALEKFLPILTALQKKGCEIRATEDIVFLMPDAKLAFEEDWSHEYLDAIVSVKTVESVEGAIAHIKRYSSGHTESIIAEDMEIVEKFFNHLDSAILLHNASTQFADGGEFGFGAEIGIATGKMHARGPIGVEQLTSFQYHIKGNGQVRP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCP39_ARATH
Sequence: MGELQDWSVTTCLLLLLFQASQIHCTSQTHVLNRLLYRSKRGFGSSVDTNHLNAIRHLSVSSPQNTSGVNQQEQKERDLIENLPGQPSVSFRQYGGYVTVNESAGRSLYYYFVEATKTKKSLPLVLWLNGGPGCSSLYGAFQELGPFRIYGDGKTLYTNPYSWNNVANILFLESPVGTGFSYTNTESDLENPGDMKAAADKYIFLVKWLERFPEYKGREFYIAGESYAGHYVPQLAQTILVHNKNQNFINLRGILIGNPTLNDIVETTGSFDYLVSHALLSQDSLLSYKENCATDTPKMEVDCIALSMKIDDDIKKMNLYNILTPTCINATLTPLTNQSKECTTVLQYEPCGMQYIAAYLNREDVQRSMHVTKLPHTWMLCNEATGFNWNQTDYSASMLPILKELMKHDQLRVWVYTGDTDTVIPLTVTMHALKMMNLTAVTDWLPWFSEGQVGGFTEEYKGNFRYATVIGAGHEVPLYKPKAALTLFKHFIRNSPLPLTP
What is the function of this protein?
Probable carboxypeptidase.
What are the official names of this protein?
Serine carboxypeptidase-like 39.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ACBD4_HUMAN
Sequence: MGTEKESPEPDCQKQFQAAVSVIQNLPKNGSYRPSYEEMLRFYSYYKQATMGPCLVPRPGFWDPIGRYKWDAWNSLGKMSREEAMSAYITEMKLVAQKVIDTVPLGEVAEDMFGYFEPLYQVIPDMPRPPETFLRRVTGWKEQVVNGDVGAVSEPPCLPKEPAPPSPESHSPRDLDSEVFCDSLEQLEPELSSGQHLEESVIPGTAPCPPQRKRGCGAARRGPRSWTCGCWGQFEHYRRACRRCRRGCRAWRACPGPLSSLTLSVRLE
What is the function of this protein?
Binds medium- and long-chain acyl-CoA esters and may function as an intracellular carrier of acyl-CoA esters.
What are the official names of this protein?
Acyl-CoA-binding domain-containing protein 4.
Protein: LPLA_ESCF3
Sequence: MSTLRLLISDSYDPWFNLAVEECIFRQMPATQRVLFLWRNADTVVIGRAQNPWKECNTRRMEEDNVRLARRSSGGGAVFHDLGNTCFTFMAGKPEYDKTISTSIVLNALNALGVSAEASGRNDLVVKTAEGDRKVSGSAYRETKDRGFHHGTLLLNADLSRLANYLNPDKKKLAAKGITSVRSRVTNLTELLPGITHEQVCEAITEAFFAHYGERVEAEIISPDKTPDLPNFAETFARQSSWEWNFGQAPAFSHLLDERFTWGGVELHFDVEKGHITRAQVFTDSLNPAPLEALAGRLQGCLYRADMLQQECEALLVDFPEQEKELRELSAWMAGAVR
What is the function of this protein?
Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.
What are the official names of this protein?
Lipoate-protein ligase A, Lipoate--protein ligase.
What is the protein family that this protein belongs to?
Belongs to the LplA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDE7B_HUMAN
Sequence: MSCLMVERCGEILFENPDQNAKCVCMLGDIRLRGQTGVRAERRGSYPFIDFRLLNSTTYSGEIGTKKKVKRLLSFQRYFHASRLLRGIIPQAPLHLLDEDYLGQARHMLSKVGMWDFDIFLFDRLTNGNSLVTLLCHLFNTHGLIHHFKLDMVTLHRFLVMVQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASFLTPLDIMLGLLAAAAHDVDHPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRESRLLAHLPKEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHNKDLRLEDAQDRHFMLQIALKCADICNPCRIWEMSKQWSERVCEEFYRQGELEQKFELEISPLCNQQKDSIPSIQIGFMSYIVEPLFREWAHFTGNSTLSENMLGHLAHNKAQWKSLLPRQHRSRGSSGSGPDHDHAGQGTESEEQEGDSP
What is the function of this protein?
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes (PubMed:10814504, PubMed:10872825).  May be involved in the control of cAMP-mediated neural activity and cAMP metabolism in the brain (PubMed:10814504).
What are the official names of this protein?
cAMP-specific 3',5'-cyclic phosphodiesterase 7B.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase family. PDE7 subfamily.
Protein: TOLB_RICCK
Sequence: MRNIIYFILLLFSCTGYALETINIECGRADPTPIAVNKFDADTSTNNIVGHDVVKVISNDLKLSGLFHPISSASFIEDKTGIEDKPLFAAWRQINASLLVNGEVKKLESGKLKISFILWDTLLEKQLVGEILEVPENLWRRAAHKIADKIYEKITGDAGYFDTKIVYVSESSSLPKIKRIALMDYDGANNKYLTNGTSLVLTPRFARSVDKIFYVSYATKRRALIYEKDLKTGKESIVSDFAGISFAPRFSPDGRKAVMSIAKNGSTHIYEIDLATKQLHKLTDGFGINTSPSYSPDGKKIVYNSDRNGVPQLYIMNSDGSNVKRISFGGGSYAAPSWSPRGDYIAFTKITRGEDGSKTFNIGIMKAYPQDDENSERIITSGYLVESPCWSPNGRVIMFAKGWPSRAKVPGKNKIFAIDLTGHNEREIITPEDASDPEWSMVLN
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: HIS8_SYNC1
Sequence: MNPMRKNIAEMAGYVPGFQPRDEQNYTKLNTNENPYPPSPKVIEAILAEVGDNLRKYPDAASRAGCEEAGRLYGFDPDWVIMANGSDEVLNNLIRAFAGEGEEIAYVHPSYSYYSTLAEIQGAKVRTFLLDEGWALKDFPERYTGKLFFLTNPNAPLGFCYPQEFIEELAGRVDGMLVVDEAYADFAKENSLDLVRRLPNVVVTRTFSKSYSLAGMRLGLAIAHPEVIAALNKIRDHYNLDRLAQTACVAALADQEYFQQCVSKIRETRDWFSAELRVLDWDVIPSHGNFVFATPPDRNGKRVYDALFERRILVRYFSDPVLSHGLRISVGTREEMEKTLAALADIG
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: RECF_PSEPG
Sequence: MSLRRIMVTAVRNLHPVTLLPSPRINILYGANGSGKTSVLEAVHLLGLARSFRSSRLNPVIQYEQPACTVFGEVELTEGGTCKLGVSRERQGEFTIRIDGQNARSAAQLAELLPLQLINPDSFRLLEGAPKIRRQFLDWGVFHVEPRFLPAWQRLQKALRQRNSWLRHGTLDPASQAAWDRELCLASAEIDEYRRNYIKALKPVFERTLSELVELDGLTLSYYRGWDKDRELQEVLASSLLRDQQMGHTQAGPQRADLRLRLAGNNAADILSRGQQKLVVCALRIAQGHLVSQARRGHCIYLVDDLPSELDDQHRRALCRLLEELRCQVFITCVDHELLREGWQTETPVALFHVEQGRITQTHDHRE
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 6PGL_MYCTO
Sequence: MSSSIEIFPDSDILVAAAGKRLVGAIGAAVAARGQALIVLTGGGNGIALLRYLSAQAQQIEWSKVHLFWGDERYVPEDDDERNLKQARRALLNHVDIPSNQVHPMAASDGDFGGDLDAAALAYEQVLAASAAPGDPAPNFDVHLLGMGPEGHINSLFPHSPAVLESTRMVVAVDDSPKPPPRRITLTLPAIQRSREVWLLVSGPGKADAVAAAIGGADPVSVPAAGAVGRQNTLWLLDRDAAAKLPS
What is the function of this protein?
Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
What are the official names of this protein?
6-phosphogluconolactonase, 6PGL.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.