PharMolix/UniProtQA huggingface dataset:
Protein: SAXO1_HUMAN
Sequence: MKTKCICELCSCGRHHCPHLPTKIYDKTEKPCLLSEYTENYPFYHSYLPRESFKPRREYQKGPIPMEGLTTSRRDFGPHKVAPVKVHQYDQFVPSEENMDLLTTYKKDYNPYPVCRVDPIKPRDSKYPCSDKMECLPTYKADYLPWNQPRREPLRLEHKYQPASVRFDNRTTHQDDYPIKGLVKTISCKPLAMPKLCNIPLEDVTNYKMSYVAHPVEKRFVHEAEKFRPCEIPFESLTTQKQSYRGLMGEPAKSLKPLARPPGLDMPFCNTTEFRDKYQAWPMPRMFSKAPITYVPPEDRMDLLTTVQAHYTCPKGAPAQSCRPALQIKKCGRFEGSSTTKDDYKQWSSMRTEPVKPVPQLDLPTEPLDCLTTTRAHYVPHLPINTKSCKPHWSGPRGNVPVESQTTYTISFTPKEMGRCLASYPEPPGYTFEEVDALGHRIYKPVSQAGSQQSSHLSVDDSENPNQRELEVLA
What is the function of this protein?
May play a role in the regulation of cilium length.  Stabilizes microtubules at low temperature.
What are the official names of this protein?
Stabilizer of axonemal microtubules 1.
What is the protein family that this protein belongs to?
Belongs to the FAM154 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, flagellum axoneme. Note=In multi-ciliated cells, localizes to the basal bodies and in non-ciliated cells, to the centrosome. In spermatozoa, colocalizes with microtubules along the length of the axoneme from its proximal end to its distal tip and with tubulin at the distal end of the flagellum and at the proximal centriole.
Protein: IPT4_ARATH
Sequence: MKCNDKMVVIMGATGSGKSSLSVDLALHFKAEIINSDKMQFYDGLKITTNQSTIEDRRGVPHHLLGELNPEAGEVTAAEFRVMAAEAISEITQRKKLPILAGGSNSYIHALLAKSYDPENYPFSDHKGSICSELKYDCCFIWIDVDQSVLFEYLSLRLDLMMKSGMFEEIAEFHRSKKAPKEPLGIWKAIGVQEFDDYLKMYKWDNDMDKWDPMRKEAYEKAVRAIKENTFQLTKDQITKINKLRNAGWDIKKVDATASFREAIRAAKEGEGVAEMQRKIWNKEVLEPCVKIVRSHLDQPINYYYYYFYLLKRFLSLN
What is the function of this protein?
Involved in cytokinin biosynthesis.  Catalyzes the transfer of an isopentenyl group from dimethylallyl diphosphate (DMAPP) to ATP and ADP, but not to AMP.  Has no DMAPP:tRNA isopentenyltransferase activity.
What are the official names of this protein?
Adenylate isopentenyltransferase 4, AtIPT4, Adenylate dimethylallyltransferase 4, Cytokinin synthase 4.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: ALKB_ACIAD
Sequence: MNAPVHVDQNFEEVINAARSMREIDRKRYLWMISPALPVIGIGILAGYQFSPRPIKKIFALGGPIVLHIIIPVIDTIIGKDASNPTSEEIKQLENDPYYARLVKSFIPLQYIANVYACYLVSRKKTSFIDKILLGISMGAINGIAVNTAHELSHKADRLDHILSHLALVPTGYNHFRIEHPYGHHKRAATPEDPASSQMGETFYEFWPRTVFGSLKSAIEIETHRLKRKGKKFWSKDNELLQGWGMSAAFHSSIIAIFGKGTIPYLVTQAFYGISLFEIINYIEHYGLKRQKRADGNYERTMPEHSWNNNNIVTNLFLYQLQRHSDHHAYPTRPFQALRHFDEAPELPSGYASMLLPAMIPPLWFKMMDKRVFEHYKEDLTKANIYPKRRAKILAKFGLTDPNIENGK
What is the function of this protein?
Catalyzes the hydroxylation of n-alkanes in the presence of a NADH-rubredoxin reductase and rubredoxin.  It preferably hydroxylases long-chain-length alkanes with at least 12 carbon atoms.
What are the official names of this protein?
Alkane 1-monooxygenase, Alkane hydroxylase, AHs, Terminal alkane hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DXS_STRGG
Sequence: MDLLTRIKGPRDLDRLSLGELDQLAQEIRTFLVDAVSKTGGHLGPNLGVVELTIALHRVFESPRDKVLWDTGHQSYVHKLLTGRQDFSRLKSKGGLSGYPSRAESDHDVIENSHASGVLGWADGMAKANEVLRKDDHVVAVIGDGALTGGMAWEALNNIAAAKDRPLVIVVNDNERSYAPTIGGLANHLATLRTTDGYERFLARGKDILERTPVVGRPLYETLHGAKKGLKDFIAPQGMFEDLGLKYVGPIDGHDIEALESALQRAKRFRGPVIVHCLTEKGRGYTPALEDEADRFHAVGKIHPDTGLPISTSGLDWTSVFGEEMVKLGEEREDIVAITAAMLQPVGLGKFEAAFPDRIYDVGIAEQHGAASAAGLATGGLHPVFAVYATFLNRAFDQVLMDVALHKCGVTFVLDRAGITGTDGASHNGMWDMSILQCVPTLRIAAPRDADQVRAQLREAVAVDDAPTVVRFSKGAVGPAVKAVGRAGGMDILRRPTAARPDVLIVSVGALAPMCLEIADLLDAQGISSTVVDPRWVKPVDEALAPLAERHRVVVTVEDNSRAGGVGSAVAQSLRDAGVDVPLRDFGIPPVFLDHASRGEVMAEIGLTAPDIARQVTGLVAKLDGRFESRAVEPARD
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: RL14_BDEBA
Sequence: MIQMQTRLNVADNSGAKEVMCVKVLGGSKRRVASIGDVIVVSIKEALPNAKVKKGDVAKAVVVRTVAKLRRPDGSYIRFDDNSAVLINASKEPIGTRIFGPVARELRAKSFVKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: G6PI_JANSC
Sequence: MGEIWSELKAHHSAKSRRKMLDLFEKGNRVQAFSATVDGLYFDFSKTNLDDGALSLLLELARVKGVESRRAAMFAGDKINETEGRAVLHTALRAPAGPIKVDGQDIMPGVLETRARCFTFAQQVRDGSFTAQGGRITDVVNIGIGGSDLGPAMATLALAPYHDGPRLHYVSNVDGADMNGALQGIDPKTTLVIVASKTFTTIETMTNAQTARDWMAQDVADPSAQFVALSSSTEKAGAFGIPPERTFGFEDWVGGRYSLWGPIGLGLMIAIGPEAFQQFLDGAATMDRHFQEADLADNLPVLLALVGMWHNQVEGHATRAVLPYDNRLSRLPAYLQQLEMESNGKSVAMDGSALQQNSGPVVWGEPGTNGQHAFYQLIHQGTRVVPCEFLVAAKGHEPDLTHHHRLLVANCLAQSEALMRGRSMEEARALMAAKGLEGAELERQAAHRVFPGNRPSTTLLYDQLTPFTLGQIIALYEHRVFVEGVILGINSFDQWGVELGKELATALEPVLTGKDDGAGKDGSTLALVDAVKAVGGI
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_PYRFU
Sequence: MRVMTSRDAQLYELKKKIDELKKIRGRGTELISLYIPAGYDLSKVMQQLREEYSTAQNIKSKTTRKNVLGALERAMQHLKLYKQTPENGLALFVGNVSEMEGVTDIRLWAIIPPEPLNVRLYRCDQTFVTEPLEEMLRVKEAYGLITVEKNEATIGILRGKRIEVLDELTSNVPGKTRAGGQSARRYERIREQETHEFMKRIGEHANRIFLPLLESGELKGIIVGGPGPTKEEFVEGDYLHHELKKKIIGIVDISYHGEYGLRELVAKAADILRDHEVIRERNLVNEFLKHIVKDTGLATYGEREVRKALELGAVDTLLISEGYDKVRVHVKCNNCGWEELKTMSEEEYEAYKKRIQTCPKCGSQNLTFEKWEVAEELIKIAEEAGSNVEIISLDTEEGQQFYRAFGGLGAILRFRIQGV
What is the function of this protein?
Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
What are the official names of this protein?
Peptide chain release factor subunit 1, Translation termination factor aRF1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3HAO_ASHGO
Sequence: MLNTTPINIDAWLAENSHLLQPPVNNFCLHRGGFTVMLVGGPNERTDYHVNPTPEWFYQKTGAMTLRIVDEQLSGAARFRDVTIREGDSFLLPANVPHNPVRYADTVGIVVEQDRPAGHFDQLRWYCRGCRELVCKYEFYMSDLSSQVREGIERFAASAEDRVCKHCGTLNYPTPQASAT
What is the function of this protein?
Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
What are the official names of this protein?
3-hydroxyanthranilate 3,4-dioxygenase, 3-hydroxyanthranilate oxygenase, 3-HAO, 3-hydroxyanthranilic acid dioxygenase, HAD, Biosynthesis of nicotinic acid protein 1.
What is the protein family that this protein belongs to?
Belongs to the 3-HAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACP_STRR6
Sequence: MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISEIEDAFDIQIEAENDLKTVGDLVAYVEEQAK
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ODP2_SOLTU
Sequence: ISAEAPLYAEVGMPALSPTMT
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
What are the official names of this protein?
78 kDa dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, 78 kDa dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex, Pyruvate dehydrogenase complex component E2 1, PDC-E2 1, PDCE2 1.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoacid dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: BRK1_MAIZE
Sequence: MGRGGGMGNPVNVGIAVQADWENREFISNISLNVRRLFDFLLRFEATTKSKLASLNEKLDILERKLEVLEVQVGSATTNPSVFN
What is the function of this protein?
Promotes multiple, actin-dependent cell polarization events in the developing leaf epidermis.  Involved in regulation of actin and microtubule organization.  Part of a WAVE complex that activates the Arp2/3 complex.
What are the official names of this protein?
Protein BRICK1.
What is the protein family that this protein belongs to?
Belongs to the BRK1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: DCTA_KLEP3
Sequence: MKTSIFKSLYVQVLTAIAIGILLGHFYPELGAQMKPFGDAFVKLIKMVIAPVIFCTVVTGIAGMESMKAVGRTGAVALLYFEVVSTIALIIGLIIVNVVQPGAGMNVDPSTLDAKAVAVYAEQAKDQGVVAFLLDVIPGSVIGAFASGNILQVLLFAVLFGFALHRLGSKGQLIFNVIESFSQVIFGIINMIMRLAPIGAFGAMAFTIGKYGVGTLVQLGQLIICFYITCILFVVVVLGSIARATGFSIFKFIRYIREELLIVLGTSSSESALPRMLDKMEKLGCRKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNSHMDIFHQITLLVVLLLSSKGAAGVTGSGFIVLAATISAVGHLPVAGLALILGIDRFMSEARALTNLVGNGVATVVVAKWVKELDAKQMDDVLNNRVPANKSHELSS
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL18_TREDE
Sequence: MDKKRNDKDRKRFKRKMHIRKSIFGTAERPRMTVFRSNKRISVQVIDDVEGKTLAAVSTMEEALRSLKVNVESGAKVGEEIGKRLKEKNIDTVVFDRNGYLYHGVVKAVADGARKTGIKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RRN5_YEAST
Sequence: MEHQQLRKYVELYNKEVEEFYNGAASGRPAEFHPSKVHVKSIHEKAGTANAGVEISSVGVDWDSEEKNTFFWCLSRYSIHRVDEWRSLLPRKSAMEILGYYRLLRRASASARSRKAGDDGAPIAYEMSAEWVALETKLSETVMAITEGAAEVADEEGHCEGLIDYESWKRRWVAIYSHSRIAEIRPLPRHALPLSRSATQTLERCVSRYTRTLLWCTALAGMASRSVSARAAESRGHKSLPTVVTRRQVERALCTEARSRDLHVLPRRIVLTLRKWELDYPREGKLFRTKEMAHLFLQSQLSRRDAPPVHQDENQENQENQENQEQDNTASEGESEAERDEIDEADLFRSALHENQLLKWLSK
What is the function of this protein?
Component of the UAF (upstream activation factor) complex which interacts with the upstream element of the RNA polymerase I promoter and forms a stable preinitiation complex.  Together with SPT15/TBP UAF seems to stimulate basal transcription to a fully activated level.
What are the official names of this protein?
RNA polymerase I-specific transcription initiation factor RRN5.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: VRK1_CAEEL
Sequence: MPPKKAPAKKLHELAAEVRVGHKINDISKKTFIVGKQFATGGFGRIHTCTEEGKSQQMVMKIEPSTNGPLLTEVVVFNRILKKELIESYKKKKKISWIGLPYLIANGYFTYESEKMRYMIIPKYATSLEAVRETNGGTLAMKDSLTVASCILDALEYLHESDYAHADVKAANILLEKQGVYSTAVLVDFGLAHRTTNNVDKPDKKRAHNGTCIFTSTDAHRGNNPSFRGDIEILAYNLMMWATGTLPWMALESSPEKVFDAKQKFIAGLPGTLQNVLKNESSAVVGCIASMFDISMKTNYTDKVDMGKLKKLVTDAIQKTSSDGKKTPTRQKKLAEEDKNAVTPKRSTRRLAVKEESDNKDNDEVEVKPEKKATPRKRTTRKAVEVNNDSDDNEEQYENPKSKSSRTQTKSKRAKEEDVDDEEEIIIPKSSRSRSKVQLSGEGSDVTTPSSAASTSRSRSIRLGLTSSTASSNKVAKKIEQKYKRLSMNKSSLVPVTISVASDKSPTTSTPSSSSGLRSKRKSSEDVGEGITLKTQVLITPAIKKAKTKSGISSATKASPTELRRVPGVRNFPKGRRSMIIKETSAKYKERLASRQTKPTFDDSSCSSEV
What is the function of this protein?
Serine/threonine kinase that phosphorylates baf-1, thus regulating the association of baf-1 with chromatin and nuclear membrane proteins during nuclear envelope formation.  May act through the egl-17 signaling pathway.  Essential in hermaphrodites for formation of the vulva, uterus, and uterine seam cells and for development and maintenance of the somatic gonad and thus the germ line.  Acts to prevent cep-1 from triggering an inappropriate cell cycle arrest, thereby promoting germ cell proliferation.  Regulates anchor cell polarity and the timing of anchor cell invasion through the basement membranes separating vulval and somatic gonadal cells during the L3 larval stage.
What are the official names of this protein?
Serine/threonine-protein kinase VRK1, Vaccinia-related kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. VRK subfamily.
What are the subcellular locations of this protein?
Nucleus. Note=Nuclear during interphase, accumulates at the nuclear rim in prophase and localizes to chromatin throughout metaphase, anaphase and telophase.
Protein: TRUA_CROS8
Sequence: MSESLEKPVVKIALGIEYDGSKYYGWQRQQEVRSVQEKLEKALSQVANEPINVFCAGRTDAGVHATGQVVHFETTAIRKDAAWTLGVNANLPGDIAVRWVKDVPAEFHARFSATARRYRYVIYNHRLRPAVLSQGVTHYHLPLDAERMHRAAQCLIGENDFTSFRAVQCQSRTPWRNLMHINVERFGAYIVVDIKANAFVHHMVRNIVGSLMEIGCGNQPESWMAELLAAKDRTLAAATAKAEGLYLVSVDYPAQFELPKPPMGPLFLAD
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: NCPP_PECAS
Sequence: MYHVVAATTNPAKIKAISLAFIDVFGAENCRIEGVDVDSGVPRQPLGSIETRTGARNRVMMARQVRPEANFWVGVEAGIEESMTFAWMVIENANLRGESRSASLVLPESILHGIREGRELGDEMERLTGVQNIKHKGGAIGVFTDGKLSRTSVYHQALLLALVPFHNPIYQISVQTTTQ
What is the function of this protein?
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives.  Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine/xanthosine triphosphatase, ITPase/XTPase, Non-canonical purine NTP phosphatase, Non-standard purine NTP phosphatase, Nucleoside-triphosphate phosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the YjjX NTPase family.
Protein: NUDC_PSEE4
Sequence: MSARWTTAVLDPQTTGGWAVARSPEGFLVDANGALFPRDWLKRQELDVLCEHGIGHFDGQPVFLLELRTASEVQGCNWQGLRRFMLEGDFDTYKVLGYAAQIGTWAREHRFCGSCGQPMTQIHWERAMYCQPCDLRSYPRISPSMIVLITRGDEVLLARSPRFVTGVYSTLAGFAEPGESAEECLVREVREEVAIEVRNIQYVGSQCWPFPHSMMLGFHAEYAGGEIVMQPDEIEDAQWFSVHDLPPLPAGRSIARYLIDLYVARRLGLAEPVLPA
What is the function of this protein?
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.  The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing.  Has preference for mRNAs with a 5'-end purine.  Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.
What are the official names of this protein?
NAD-capped RNA hydrolase NudC, DeNADding enzyme NudC, NADH pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudC subfamily.
Protein: NRDR_SHISS
Sequence: MHCPFCFAVDTKVIDSRLVGEGSSVRRRRQCLVCNERFTTFEVAELVMPRVVKSNDVREPFNEEKLRSGMLRALEKRPVSSDDVEMAINHIKSQLRATGEREVPSKMIGNLVMEQLKKLDKVAYIRFASVYRSFEDIKEFGEEIARLED
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: RIBA_SHEDO
Sequence: MSINYIATSKLPTPWGVFSMHGFEDTQTGKEHVALTFGEWQPSHAILGRIHSECLTGDALFSLRCDCGFQLQTAMQNIAEAGQGFILYLRQEGRGIGLLNKIRAYELQDAGANTVEANERLGFDADMRKYDMIAPMLEKIAVTQVKLMTNNPRKVKAMQDLGIVVAERVPLQVGKNRYNEAYLKTKSTELGHMMSEHHFNDDKGN
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: ISPF_CROS8
Sequence: MRIGHGFDVHAFGGTGPIILGGVRIPYEQGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMAPHIPQMRVFIAEDLGCHMDQVNVKATTTEKLGFTGRGEGIACEAVALLMKAGA
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: CUA1_DROME
Sequence: MKFAVAVIFTLALAMGVQSSVIPLLSQVAGHGLSYTAVSGPAVVASPWAVPAAHWPAAVNVASWPPAAIHAAAPAVLAAPAPAVVAAHAPSVVVAPVAHSGVYTAQTRGAIHTAPLAGHIQSVASINAAPAPGTL
What is the function of this protein?
Component of the cuticle of the adult fruit fly.  Could be involved in thickening of the hard adult cuticle.
What are the official names of this protein?
Adult cuticle protein 1, dACP-1.
Protein: THEM4_RAT
Sequence: MLRSCAMRLRTLGATPARRPEATRRLFSSEEVVCKDYALPNPSWTKDLRLLFDQFMKKCEDGSWKRLPSYRQNPPQALQEFQTHFVDSKFKKEEQMSKAQQFTRSLEEGLGFEYAMFYNKAEKRIVCLFQGGLHLQGMPGFVHGGAIATIIDITAGMCAFSEGIVMTANLNIDYKKPIPLLSVVVVNSQLQKIEGRKLFVSCTIQSTDEKTLHTQATALFIKLDPDKPLT
What is the function of this protein?
Has acyl-CoA thioesterase activity towards medium and long-chain (C14 to C18) fatty acyl-CoA substrates, and probably plays a role in mitochondrial fatty acid metabolism (By similarity).  Plays a role in the apoptotic process, possibly via its regulation of AKT1 activity (By similarity).
What are the official names of this protein?
Acyl-coenzyme A thioesterase THEM4, Acyl-CoA thioesterase THEM4, Thioesterase superfamily member 4.
What is the protein family that this protein belongs to?
Belongs to the THEM4/THEM5 thioesterase family.
What are the subcellular locations of this protein?
Cell membrane. Cell projection, ruffle membrane. Cytoplasm. Mitochondrion. Mitochondrion inner membrane; Peripheral membrane protein. Mitochondrion intermembrane space. Note=Released from the mitochondria into the cytosol in response to apoptotic stimuli.
Protein: COTC_BACSU
Sequence: MGYYKKYKEEYYTVKKTYYKKYYEYDKKDYDCDYDKKYDDYDKKYYDHDKKDYDYVVEYKKHKKHY
What are the official names of this protein?
Spore coat protein C.
What is the protein family that this protein belongs to?
To B.subtilis protein YnzH.
Protein: Y9128_RHOBA
Sequence: MNASSSETLEVVDDRFQKDRSWTVAWIAGLIVVGMVLVLAGMGRRFWCECGSWVPWSWDIWTAHNSQHLIDPYFFSHVLHGVLFYWALRWVPRLNRTQCLLIALGLEASWEILENSPLIIERYREATMAVGYTGDSIANSVTDVAACMLGYWFSSRFPWRWSVALFVVSEILMLIMIRDNLLLNVLMLVSPIPAIQEWQSG
What are the official names of this protein?
UPF0314 protein RB9128.
What is the protein family that this protein belongs to?
Belongs to the UPF0314 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: M28P2_ARTGP
Sequence: MHLSMGGLLPGLALLASANALALALPLESSVYTVQVTNPFHESLFSCPAASWPKVKLGSENRSQEPSKDLKKILSQISPKRIEATIRKLVSFGTRHTLSTQTNATYGIGAARDWIESEFQRYANASDGRLTVAVVGYDQQPDGRRIPFPVRISDVVATLKGEGDPERVYLVSGHYDSRNSDALDYKGIAPGANDDASGVAVSLELARVMSQRGLPRPKATIVFAAVAGEEQGLYGATFLAQSYRNSSANIEGMFTNDIIGSSTADDGTREPHVVRLFAQGIPPLNVEDQAMRERRIMIGGDNDTPARQLARFVKETAENKHTDMEVSVIYRLDRYLRGGDHRPFLEAGYPAARFTEPNENFAHQHQDIRIDKDPKTGMDIQYGDLPEFCDFDYISRVGKVNAAALWNLAMSPGMPRNVRVNTSDLTNDSKFTWDPPAGGNALVGGYEIVWRSTNAPFWTHKMDVGMVQEATIDLSKDNVIFGIRARGKNGERGVAVLPFP
What are the official names of this protein?
Probable zinc metalloprotease MGYG_02393.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family. M28B subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PRP4_BOVIN
Sequence: MASTRPSSTATKTKAPDDLVAPVVKKPHIYYGSLEEKERERLAKGESGLLGKEGLKAGIEAGNINITSGEVFEIEEHISERQAEVLAEFERRKRARQINVSTDDSEVKACLRALGEPITLFGEGPAERRERLRNILSVVGTDALKKTKKDDEKSKKSKEEYQQTWYHEGPHSLKVARLWIANYSLPRAMKRLEEARLHKEIPETTRTSQMQELHKSLRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDQKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVTWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWMAE
What is the function of this protein?
Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).
What are the official names of this protein?
U4/U6 small nuclear ribonucleoprotein Prp4, U4/U6 snRNP 60 kDa protein, WD splicing factor Prp4.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle.
Protein: IF3_PSEPW
Sequence: MTIKREMRNDKRAAPKAPINENISAREVRLIGADGEQVGIVSIDEALRIADEAKLDLVEISADAVPPVCKVMDYGKHLFEKKKQANEAKKNQKQIQIKEIKFRPGTEDGDYQVKLRNLVRFLTDGDKAKISLRFRGREMAHQELGMELLKRVEADLAEYGTVEQHPKMEGRQLMMVIAPKKKK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCKA_ALISL
Sequence: MTVMEHKKAAQLDLSQHGLSNVTEVLRNPSYDVLFEEETRPDLEGYERGVMTELGSVAVDTGIFTGRSPKDKYIVKDETTKDTLWWSDQGKNDNKAITPAVWDDLKALVTEQLSGKRLFVIDGFCGANPDTRLSVRVITEVAWQAHFVKNMFIRPTDEELESFEPDFVVMNGAKATNPNYEAQGLNSENFVAFNLTERVQIIGGTWYGGEMKKGMFAMMNYLLPLKGIASMHCSANVGKEGDVAVFFGLSGTGKTTLSTDPKRQLIGDDEHGWDDDGIFNFEGGCYAKTIRLSKEAEPDIFNAIRRDALLENVTVRNDGSIDFDDGSKTENTRVSYPIYHIDNIVKPISKAGHANKVIFLTADAFGVLPPVAKLTPEQTKYHFLSGFTAKLAGTERGITEPTPTFSAAFGAAFLTLHPTQYAEVLVKRMEAAGAEAYIVNTGWNGTGKRISIQDTRGIIDAILDGSIDNVETKNIPVFNLEVPTSLPGVDTSILDPRDTYTDPLQWDSKAEDLAQRFIKNFAQYTDNDEGKALVKAGPQLD
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.