PharMolix/UniProtQA huggingface dataset:
Protein: GLMU_XANOM
Sequence: MTLPLHVVILAAGEGKRMRSSLPKVLQPLAGQPMLAHVIATARQLQPAAIHIVYGHGSDQVQAAFADQSDLQWAAQREQLGTGHAVQQAMPAIPDAARVLVLYGDVPLIRSESLLQLLHAPGRMAVLVAELANPTGYGRILRDAEGKVAAIVEQKDANDEQRRIRTINTGILTAESTALRRWLGGLSNDNAQGEFYLTDVFASAAADFTPADMVHVADPQDVEGANDPWQLAQLERAWQLRAARALSLQGVRMADPARVEQRGSVQVGRDVQLDIDVILEGEVTLGDDVVIGPFVRLRDVTLGAGTQVRAHSDLEGVITEGAVQIGPFARLRPGTVLADGVHIGNFVETKKVTMGVDSKANHLTYLGDAVIGSKVNIGAGTITCNYDGVNKSQTTIGDGAFVGSNSALVAPIEIGANSTIGAGSVVTRDAPAGQLTVTRARQTVIEGWERPTKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPL_WIGBR
Sequence: MNSINADLLYISAAIIMGFASIGAAIGIGILGGKFLEGAARQPDLIPTLRTQFFIVMGLVDAIPMISVGLGLYLIFAAS
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PRL_NEOVI
Sequence: MDNKGWSLKGSLLPLLLLVSDLLLCQGVTSLPICPTGAVNCQVSLRDLFDRAVILSHYIHNLSSEMFNEFDKRYAQGRGFITKAINSCHTSSLSTPEDKEQAQQIHHEDLLNLILRVLRSWNDPLYHLVSEVRGMQEAPDSILSRAIEIEEQNRRLLEGMEKIVGQVHPGVRENEVYSVWSGLPSLQMADEDSRLFAFYNLLHCLRRDSHKIDNYLKLLKCRIVYDSNC
What is the function of this protein?
Prolactin acts primarily on the mammary gland by promoting lactation.
What are the official names of this protein?
Prolactin, PRL.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CPLX1_MOUSE
Sequence: MEFVMKQALGGATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREVMRQGIRDKYGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEPEEEDESILDTVIKYLPGPLQDMFKK
What is the function of this protein?
Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles (PubMed:23345244).  Organizes the SNAREs into a cross-linked zigzag topology that, when interposed between the vesicle and plasma membranes, is incompatible with fusion, thereby preventing SNAREs from releasing neurotransmitters until an action potential arrives at the synapse (PubMed:23345244).  Also involved in glucose-induced secretion of insulin by pancreatic beta-cells.  Essential for motor behavior (PubMed:15126625, PubMed:16000319).
What are the official names of this protein?
Complexin-1, 921-S, Complexin I, CPX I, Synaphin-2.
What is the protein family that this protein belongs to?
Belongs to the complexin/synaphin family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Perikaryon. Presynapse. Note=Enriched at synaptic- releasing sites in mature neurons.
Protein: RL22_RICPR
Sequence: MIQKNKNFATAKAKSIRVSPRKLNLVASFIRNMKVSEALVQLTFSPKRIAKIVKDCLQSAIANAENNLGLDIDRLIITKATVGKSVVMKRIMPRAKGRATRINKFFSNLYITVTEKEDN
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: BRK10_PHYSG
Sequence: GFTPFRIY
What is the function of this protein?
Produces in vitro relaxation of rat arterial smooth muscle and constriction of intestinal smooth muscle (By similarity).  May target bradykinin receptors (BDKRB).
What are the official names of this protein?
Des-Arg1,Pro2,Pro3-[Thr6]-phyllokinin, Des-Arg,Pro,Pro-[Thr6]-phyllokinin.
What is the protein family that this protein belongs to?
Belongs to the bradykinin-related peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: SPB4_CRYNB
Sequence: MDAPVPAAPAFGGSWAKLNPPLSPWILDVINSMGFKNMTPVQAGTIPRAVKNQDCVVEAVTGSGKTLAFTIPVLERLSRREEPYKKGEIAAIVVAPTRELATQIHAVFHHFLSSLIPPESEEETGDVEAHAPPFASSSRSPSPQTPDKPLFPLPMLVTSGTPTPYETFQSTHPSILIGTPGRLAAFLLNPRGLAIVRVSELDVLVLDEADRLLSSPDHRRDVERIMRHLPKQRRTHLFSATMTDAVEEMIGLGLRNPVRIVVNLKDKRKDGEEPKERRTPMALQNTYLVCRHAEKTLQLIRLLLCESTKHERSKFIVYFSTCAAVDYFYRILSRLPSLSKFHLTSFHGELPPKIRETALSTFTSHPSSHLSPAVLLCTDVAARGVDFLDIDVVIQYDAPTDPKTFSHRAGRTARAGRRGKAVVLLGKGREEDYVGTFQSANAELMKRKRQKAQRSILDFLNIRKIPLTKQPYINAYLEEVDTPQALDPEATTLLHSIRQIILTDRELSDKAAKSFVSAFRAYSKHEASFIFRTLDFDFNSQAISFGLLRLPAMPEIKDWKKKKEAERQRLEKIKSEGGEVEEKEIIEWEDAGVNWDTFAYASRQREAARLATLAQRADNQSSNDAARAEARAKRKIKAEMREAWSEQKERKVRKEERKEKKDAKKKYEWELEQANGEGDRQSDLANIAKAQAERKKRREREEESWDEEIGKEYKSLKREIKEEKSVKESSKGGAGGGGIGGGMFDDLE
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits.  Binds 90S pre-ribosomal particles and dissociates from pre-60S ribosomal particles after processing of 27SB pre-rRNA.  Required for the normal formation of 18S rRNA through the processing of pre-rRNAs at sites A0, A1 and A2, and the normal formation of 25S and 5. 8S rRNAs through the processing of pre-rRNAs at sites C1 and C2.
What are the official names of this protein?
ATP-dependent rRNA helicase SPB4.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX55/SPB4 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: GSA_LEPBJ
Sequence: MSQRSSELISDSWKGSSSEELFERAKIVSPGGVHSPVRSFRSVGGTPVFFVSANGATLTDVSGKEYVDFCLSFGPLILGHRDPEVEEVVRETAGLAWSFGTAEPYSLELAEFITNRIPWAEKVRFVNSGTEAVMSALRVTRAATGREKIFKFDGCYHGHLDALLVKAGSGLAGESSSDSAGISSTAIANTLVLPLDDEMAVQKLFESEGKNIAALIIEPLPANYGLLVQRKEFLLKIVEIAKKYGTLVVFDEVISGFRTGFQGMSGLLGIRPDLVTYGKIIGGGFPVGCYAGRRDLLDLVAPSGPVYQAGTLSANPFGMRAGLATLKKAERDSIYSVLEVRTKTFADEMVKLLNGKTDQEWEAVTHSSLFWFRKKTQQAVRRIDQIPEGHKEGFAEVFHVLLKNGIYLAPSGYEVGFLSWAHNDSVIAKVLEIADKAFKEL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE2_JANSC
Sequence: MSAPMSASTSVVTRFAPSPTGFLHVGNLRTALFNFLIAKKAGGEFILRLDDTDPERSTQAFADAIQEDMEWLGLTWDRIERQSDRFDRYAAAADELRAKNRFYEAWETPTELDLKRKKQLNMHQPPVYDRAALALTDDQKEALRAERGQGVWRFKLDHQRIEWTDGILGDLSIDAASVSDPVLIRADGQVLYTIASVVDDTDMGVTHVVRGSDHVTNTATQIQIMEALGKSAPSFAHHSLLTGPQGEALSKRLGTLALRDLREAGMEPMALLSHMARIGSSQPVELAGSVEELAEGFDLNHFGSAPTKFDVEDLWPLTASVLHGTAFEDVAGEIAALGVPADIAPAFWEVARANIGKRAEIADWWALFRDGATPLVADEDREFVAQAFAMLPDLPYDETTWSNWTSAVKEATGRKGKGLFMPLRKAVTGRERGPEMADVMRLMQVKPTL
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 2, Glutamyl-tRNA synthetase 2, GluRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNN_AERHH
Sequence: MKVGIIGAMEQEVALLRSQMSNPTTLQLGGCEFYQGTLAGKEVILTRSGIGKVAASVATSLLLEKFAPDCVINTGSAGGFAQDLHIGDVVIASEMRFHDVDVTAFGYEMGQMAQQPAAFPCDETLIAVAQDCIAEQGKHQTKVGLICTGDQFMCKPDAIAKARADFPQMLAVEMEGAAIGQVCHMFKVPYLVVRAMSDIAGKEQVESFDAFIEVAGKHSAEVIIKMLGKL
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: YIDD_PSEPU
Sequence: MRKLALVPIQFYRYAISPLMANHCRFFPSCSCYAYEAIENHGIWRGGWLAVRRLGRCHPWNDGGYDPVPPAPSSRTSSIAE
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SMC4_DICDI
Sequence: MVEDEEINDQISEEEEEKKKNNDSDEEMKDIDEEEEEEEEEEEEEEEEEKEEEEEEEEEETPKKPMPPPQSKAKPSSQPPDIKKASQQSQTQKNTPPPIQTSQSSQSSQSSQSSQQQQPKNISQTQQPKNTPPLQSSQTSQTSQKTPVSSNNGIEKRLMITKMVMENFKSYAGAQEVGPFHKCFSSVVGPNGSGKSNVIDAMLFVFGYRAKQIRLNKISELIHNSENHKNLTNGRVSVHFQEIIDLPGEDNYEVVKGSEFVVTRTAQKTGNNKDGVSKYYLNDKVVKLDDLKTILKDKGIDLDNNRFLILQGEVEQIAMMKPKGVHPGEEGLLEYLEDIIGSKKYLPDIEATSKLIEDIGDKRTSSNNRMKVVEKEKDALQQERDNALEYIDKELKLIHCKSIHYQIGRSKPEREKNEIAAKQEMVEKQLEQELVTQKASNDKLLEFEKNLKQQNKQLDELNKQMAKCKNELLTTEKKGVKYKEETKHLKTKVKKNNSVIEEETKKQAEFERSTIIHKQDIVRFEKEYVELPKELIVEEKKLESMLNSLKGEVTELQREMEEKQKQLLPWSKKHSEAKAVVDLKTSELAVLSKDFNGATQNLDDAIKALEDAKTISSTRKNNITKSKKELESVKAIIVDLEKRLASGKVTEENLYRNTMDAKRQLEQIKTNLSENSSRNTILDRLLKIKESGQISGIHGRLGDLGAIDQKYDVAISTAAFSQMDNIIVETTAAAEACVELLRKENLGRATFMILENLEYQRQNLGPVQTPNNTPRLFDLIKMKDEKKYATAFFTAVGHTLVADTLDEATKIAYGAKRHRVVTLDGSLIDTSGAMSGGGLKPRVGAMNSKLKGDPKEDKKKLIELQDNLSQLDSDLRQCRDELVEIENQIQQAQNRRSELELELPKMDMDIKAAITKCEELTKVIPQLKNKAKLSTEKKEQIDSIKESLIVDQKSLDKVQEKVNKLESEVQEIQNSILNVGGPQLKMQKNKVESLQSRIDSNQTNTTKANVQIKSLAKSMEKSIKILNENTKEKDENEAALAEILEKYKSLEKENLKATEAMEAVSEQLREKEEETKEIRKEHEKAKKVIEKIKVSNSKLETQIEEFKTLINEKQAEIADCLSKFANQAKKAKIYKDYVDESLINQVSAILTPEEIEQYMEATEQQNLIAKIHELTTQIQKISKENNVNIEVVKDFQKKEQEYHSRKAEFDEIEKERDNLSKRYESLRKNRLDEFMAGFTIITMKLKEIYQMITLGGDAELEIIDREDPFQEGISFSVRPPKKSWKNISNLSGGEKTLSSLALVFALHHYKPNALYVMDEIDAALDFKNVSIIANYIKERTKNAQFIIISLRNYMFELADRLVGIYKTDNCTKSVTINPNSFTSLSTTTTTTNNSQQQQQQKQQQKQQQQNSTSQK
What is the function of this protein?
Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.  The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases (By similarity).
What are the official names of this protein?
Structural maintenance of chromosomes protein 4, SMC protein 4, SMC-4.
What is the protein family that this protein belongs to?
Belongs to the SMC family. SMC4 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RUVA_CROS5
Sequence: MISYLKGSPIEVIKNTNNRVILVLEVNEIGYELQIPSKLGREISQEKLDTIQIFTHVQIKEDQQILYGFSTTAERELFRQLISVSGIGAQSAIALIDTLGLEELVQAIVTGNIRILSQPSGIGRKTAERIALELRTKLSQWRKMVGVTVTSSAAMPSLEILEDIEMTLLALGYTNEEINKAISTLSQDNLMLKNTNTEEWIKEAIAWLSQGT
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: RL17_CHLSY
Sequence: MRHRHAGKLLGRSYEHRKALYRNLMIALIEHKKIKTTLAKARAVQPEVEALISIAREDTPHARRMALSKLASKEAMRKLFTFAPTTYGGRNGGYTRITKLGPRRGDGAEMALIELI
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: MIAB_GLUOX
Sequence: MTTAPTSPALPASSDTAPTGPAPRGLHVITWGCQMNVYDSARMADVLRPLGYGPVERPEDADMVILNTCHIRERATEKVFSELGRLRKIRDERMSNGADRTIIAVAGCVAQAEGEVILTRAPYVDLVLGPQTYHKLPEMVARAARAGGAVIETDFPVEQKFDFLPTDAAPQTQGNLTAFLTIQEGCDKFCSFCVVPYTRGAETSRPVASVLAEARRMAESGVREITLLGQNVNAYHGDDGKGGSETLAGLVEQLAQIPGLGRIRYMTSHPRDVDQSLIDAHRDNPALMPFLHLPVQSGSDRILKAMNRGHTADEYRESVRKLREARPDLALSSDFIVGHPGETEEDFEATMQLVRDIGFAMAYSFKYSPRPGTPAAGQPMQVPEDVKDRRLAELQALLREQQDAFNADMVGTVQEILVTNRGRKPGQIAGRSPYLQPVHFDGPDHLIGSTVKVAITTRRTNSLGGTLIRETASAC
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSD_SHESA
Sequence: MDKVKIALQYMLPKHLLSRLVGKLAASEAGALTTAAIKWFIKQYKIDMSEAAQSEPEAYKSFNDFFTRALKPGIRPINTATNIMVHPVDGAVSQLGPIKDGRIFQAKGHHYSSLTLLGDQAEDAKRFEGGDFATIYLAPKDYHRIHMPIKGTLSKMTYVPGELFSVNPLTARHVPGLFARNERVVAIFETELGPLAMVLVGATIVASIETVWAGTITPPTGKQVFTWEYPTVGPDAITLDKGEEMGRFKLGSTVVMLFAKDAIDTFAEGVEPEAVTRMGQAFANLKNQASAD
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TUSC_ECODH
Sequence: MKRIAFVFSTAPHGTAAGREGLDALLATSALTDDLAVFFIADGVFQLLPGQKPDAVLARDYIATFKLLGLYDIEQCWVCAASLRERGLDPQTPFVVEATPLEADALRRELANYDVILRF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
What are the official names of this protein?
Protein TusC, tRNA 2-thiouridine synthesizing protein C.
What is the protein family that this protein belongs to?
Belongs to the DsrF/TusC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK22_OENAR
Sequence: MKKKKTYGEVYALGQYISMSAPKARRVIDQIRGRSYEETLMLLALMPYRACDPILKLVNSAAANARHNMSFNEATLVISKAEVNEGTTVKKLKPRARGRSYPIRRPTCHIRIVLQDTSFDEFEEDFFSLKKDAWEKK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RUXG_DICDI
Sequence: MTFGKQADPDLTKLLDKKLAIKLNGNRTVHGILRGFDTFMNIALKDTVEVVSPTEKYEIGMVIIRGNSILLMEPLESMAYVPKTE
What is the function of this protein?
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.  Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes.  Is also a component of the minor U12 spliceosome.
What are the official names of this protein?
Probable small nuclear ribonucleoprotein G, snRNP-G, Sm protein G, Sm-G, SmG.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Note=SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes.
Protein: H2AX_TETPY
Sequence: MSTTGKGGKAKGKTASSKQVSRSARAGLQFPVGRISRFLKHGRYSERIGTGAPVYLAAVLEYLAAEVLELAGNAAKDNKKTRIVPRHILLAIRNDEELNKLMANTTIADGGVLPNINPMLLPSKSKKTESRGQASQDI
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2AX, Histone H2A.1, H2A1, Histone H2A.X.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localizes to both the large, transcriptionally active, somatic macronucleus (MAC) and the small, transcriptionally inert, germ line micronucleus (MIC).
Protein: YFBU_SALG2
Sequence: MEMTNAQRLILSNQYKMMTMLDPTNAERYRRLQTIIERGYGLQMRELDREFGELTEETCRTIIDIMEMYHALHVSWTNLKDTQAIDERRVTFLGFDAATEARYLGYVRFMVNIEGRYTHFDAGTHGFNAQTPMWEKYQRMLNVWHACPRQYHLSANEINQIINA
What are the official names of this protein?
UPF0304 protein YfbU.
What is the protein family that this protein belongs to?
Belongs to the UPF0304 family.
Protein: LRS14_SACS2
Sequence: MQVENIRVRLPSGKEVGLVDALNFCYDISDTDFQVLKTLLNSGPKTEDELAEMLHLSKASINRSVNKLVSLGFVDRVKDSSSKGGRPRYIYKPIDADRITTKISNDFKYCADLFSSVIPQELKEK
What is the function of this protein?
Acts in transcription regulation.  Binds to multiple sequences in its own promoter.
What are the official names of this protein?
HTH-type transcriptional regulator lrs14.
Protein: YHAM_BACLD
Sequence: MAKGIMLHEVGEQVDLYLLIKSSTKGIASNGKPFLTLMLQDQSGDIEAKLWDAKQQDEVTYGPQTIVKVVGDIHHYRGRNQLKLRNIRPAGENENVKIDDFLETAPIPKNEMMDAVTQYIFEMKNPNIQRITRHLVKKYGKEFIDYPAATKNHHEFVSGLAYHVVSMLNLAKSVADLYPSLDRDLLYAGVILHDLGKVKELSGPVSTTYTVEGNLLGHISIMVTEIAKAAEELQIDSEEVLILQHLILSHHGKPEWGSPKPPMVKEAEILHYIDNLDAKINMMDRALERVKPGEYTERVFALDNRSFYKPVFHK
What is the function of this protein?
Shows a 3'-5' exoribonuclease activity.
What are the official names of this protein?
3'-5' exoribonuclease YhaM.
What is the protein family that this protein belongs to?
Belongs to the YhaM family.
Protein: FDXN_NOSS1
Sequence: MAYTITSQCISCKLCSSVCPTGAIKIAENGQHWIDSELCTNCVDTVYTVPQCKAGCPTCDGCVKVPSDYWEGWFANYNRVIAKLTKKQDYWERWFNCYSQKFSEQLQKHQGEILGV
What are the official names of this protein?
Ferredoxin-like protein in nif region.
Protein: DCTQ_PSEAE
Sequence: MHALARVWARLEEGLIAFLLAAMTLVTFVYVVLNNLYTLLYDLADLWEGGNETLLAIGDGVLTLAQEMTWSNALTKALFAWLIFLGIAYGVRTAGHLGVDVLVKLASRPVQRVLGVIACLACLGYAGLLCVASYDWVKTLFIAGIGAEDLDHFGIRQWHIGLIVPVGFALVFIRFAEILVRILRNRQTGLGLADEAADALKLTEHEEPKA
What is the function of this protein?
Part of the tripartite ATP-independent periplasmic (TRAP) transport system DctPQM involved in C4-dicarboxylates uptake.
What are the official names of this protein?
C4-dicarboxylate TRAP transporter small permease protein DctQ.
What is the protein family that this protein belongs to?
Belongs to the TRAP transporter small permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ACP_KOCRD
Sequence: MASKDEILAGLAEIVNEETGLETEAVQLEKSFTEDLDIDSISMMTIVVNAEEKFDVTIPDEEVKNLKTVEDAVNFIDNAQA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS4_YERPS
Sequence: MIIPALDLIEGKVVRLHQGDYGQQRDYGNHPLPRLQDYQQQGAQVLHLVDLTGAKDPAARQIPLLRELLAGVDVPVQVGGGIRNEQDVVALLEAGAARVVVGSTAVKQPEMVQQWFERYGAEAIVLALDVRINEAGCKHVAISGWQENSDATLEQIVEQYLPYGLKHVLCTDISRDGTLSGSNVELYQEVCQRYPQVAFQASGGIGCLDDIARLRGSGVQGVIVGRALLDGKFNVKEAIACWQNV
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECOT_PSEPF
Sequence: MGNFTVRATAGLMLASLSTLAHAAKLEDTAPYPKAEAGFTRQVIHLPQQAQEENFKVEILAGKTLEVDCNRQRLGGTLEEKNLEGWGYPFYRLEKVSGPMSTLMACPPGTQKKRVFVPVIGDGFTVRYNSKLPIVVYAPQDVEVRFRIWSASDKIGVAIPE
What is the function of this protein?
General inhibitor of family S1 serine proteases.
What are the official names of this protein?
Ecotin.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I11 (ecotin) family.
What are the subcellular locations of this protein?
Periplasm.
Protein: KDSB_NEIG2
Sequence: MTEFVVLIPARLDSSRLPGKALADIHGKPMVVRVAEQAAKSKAARVVVATDHPDIQTACQAHGIEVVMTSNRHESGTTRLAEAAAALKLPPHLIVVNVQGDEPLIAPELIDRTAEVLVENNVQMATAGHELHDFDELMNPNAVKVVLDKNGNAIYFSRAPIPYPRDAMRAGKREMPSETAVLRHIGIYAYRVGFLQRYAEMSVSPLETIESLEQLRVLWHGYPIAVETAKEAPAAGVDTQEDLDRVRAVFQTV
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPD_SYNJA
Sequence: MTETADLWPQLLGQLLERQSLSEAQAEQLMNGWLHNQVPDVVSGAILAALQAKGVSASELAGMARVLQRASLGSPLDLPLLVDTCGTGGDGAGTFNISTAVAFVVSAAGIPVVKHGNRSASGKVGSADVLEALGVNLSAEPEQVRAAVAEVGITFLFAPHWHPAMRAVIPYRRALKVRTVFNLLGPLVNPLYPNRQVIGVYAPELVPVMAEALRLLGRERAVVLHSREGLDEAGLDQPTDLGILSGGLVRTEVLNPRDYDLTPAPVQALQGGNLAENAAILAQVLQGSGAPAQRDVVALNAALALQVAGAVPDWGSGIAQAREILASGAAWDRLQKLVNFLAS
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.