PharMolix/UniProtQA huggingface dataset:
Protein: GCSP_RHOP5
Sequence: MPVSRSPIEDLANGFARRHIGPSPQEIAAMLRAVGAPSLDALMGETLPAAIRQAKPLDLGPALSEPEALAHMAELAAKNQVFTSLIGQGYYGTAMPTVIQRNILENPAWYTAYTPYQPEISQGRLEALFNFQTMICDLTGLDVANASLLDEGTAAAEAMALAERAMPKKTKAFFVDRDTHPQTLAVLRTRAEPLGWQIIVGDPVSDLQKADVFGALLQYPGSSGALRDPRPMIAALHAKGGLAVIAADLLALTLLASPGDLGADIAIGSAQRFGVPMGYGGPHAGFMAVRDSLKRALPGRIVGQSIDSHGQPAYRLALQTREQHIRREKATSNICTAQVLLAVLASMYAVYHGPEGLSAIARSIHRKTAVLAAGLRKLGFTTRNEAFFDTITVDVGDKQSEIIARARDENINLRIGDGTLGLSLDETTTPKIVEAVWRAFGGALSYAEIEPAMRDALHPTLKRTSPFMTQEVFHLYRSETELLRYMRKLSDRDLALDRAMIPLGSCTMKLNATTEMMPLSLPGFAHLHPFAPPEQALGYHALFDKLETWLAEITGYDAVSLQPNSGAQGEYAGLLAIRGYYKSRGEPHRKICLIPSSAHGTNPASAAMAGMEVVVVECNDRGDVDVDDLRARAELHSPNLAAVMITYPSTHGVFEEHIRDICDIVHAHGGQVYLDGANLNAQVGLARPGEYGADVSHINLHKTFAIPHGGGGPGMGPIGVKAHLAPFLPGHPCCDDTGPDGFSHGGGTVAAAPWGSASVLTISYVYILLMGGDGLKRATEVAILNANYVAAKLDPHFPVLYKNERGRVAHECIVDPRALKNSSGVTVDDIAKRLIDYGFHAPTMSFPVVGTLMIEPTESESKAELDRFCDAMIAIRREIAEIETGRWKVEQSPLRFAPHTVHDLAEDHWHRPYSRAIGCFPAGTARHDKYWCPVGRIDNVYGDRNLVCSCPPIEDYALAAE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: YPO4_CAEEL
Sequence: MASATTNQGNEWRFVAPININTTTENTVSCVKFDPHEDLFWIGSSTGKVTSLLPTNHFTRYSAFVVSNISGVHSLEPTESLIFTLSDTMLRATTRQGIPVAKFTSPSMTKMAASCHMPGTSTFIMGGFQEKLIHYDFVKEKEIRTTELKASENAIIIRYNGTNTFTADTRGNVFVKNSKNCETIHTLDCHQDQVLDFDVQGNKLITCGVSMNRLKNMDQFIKVYDLRMYKALSPIGMPYLPQFARFMPSYCERVCVTYQTMYNQPGQTATWSNHPAGVKMFDLNSNGNSAEFPIETSLISAFDFSSNKNFIAVGNHCGIVNVFADRDQPQVNENSKETVFAAPPVQPPLSFAIDDTTQTFGSIPLGFSQEPLVSDWPTELTQIVYRRRKPPTEQTNVKSIHYLSQIKNPRINSKLKRHNIVPYFFEQEELIEASNDHGSKEEAPQEMKRIKVSKLYKKRPLIVNQVPARRGNSQDETQETYTWNIIRHVTMQSTHGMNLVANTLVQVAYSLSPIRSIVLRHICTEDSCITCELHFLFTAFSSKIGDNSGMLTNNLAWALARNGVSLKAGGVLSATQQIIKTVIDDVARTDASGSICSKFDRHLRCIRCRGLQQQESVTDHLLKLNYAPVYQASLCQLIEKSLHIGDDSGEIECEDCKQMSRMECKRKVRELSPVLLIDTNASSNGFVEFWRRQLSLFERKPGGNRSSALGTVPESPSEKKNCRFGTDCRNKKTCKFVHGLVDWPAEQTKLLEDVDLPEWAHYIPSRIAAQLCEGIVRLSDVSDLPDYDEPSAVIYELDAMIHAVGNGENDVNWTHPVTLLRESPVISSSWTLINEQLVSRLHDHEARHIDGRWKLPALLAYKKKNFDVKTSEDIISNDLFLAEENLASNGMTSLAVQSLEELPKEKELVGLDAEFIKIKTDLLEFDGKTVQMRAVGRASCVDSTGERIIFDDHVKLTDDVEVVDYLTKFSGIVKADLCPTTSEKYLTTHKRLLLRMHVLIQRGVTFVGHALHNDFTVLNVHVAESQIIDTVTLMRLGTQRMLSLQFLVKEILGETIQMEAHDSVVDARYALKLYRKYLEIKEQGLLGSEMRRIYTILPCPSPNQTSSPLVVSTTRKTPEDTNPADAAPKSV
What are the official names of this protein?
Uncharacterized protein F31E3.4.
Protein: PPM1A_RAT
Sequence: MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLETWSFFAVYDGHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEHMRVMSEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGGSVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAPKVSAEAVKKEAELDKYLENRVEEIIKKQGEGVPDLVHVMRTLASENIPSLPPGGELASKRNVIEAVYNRLNPYKNDDTDSASTDDMW
What is the function of this protein?
Enzyme with a broad specificity.  Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling (By similarity).  Dephosphorylates PRKAA1 and PRKAA2.  Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB (By similarity).
What are the official names of this protein?
Protein phosphatase 1A, Protein phosphatase 2C isoform alpha, PP2C-alpha, Protein phosphatase IA.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol. Membrane; Lipid-anchor. Note=Weakly associates at the membrane and N-myristoylation mediates the membrane localization.
Protein: RS11_GEOTN
Sequence: MARRTNTRKRRVRKNIDTGIAHIRSTFNNTIVTITDVHGNAIAWSSAGALGFKGSRKSTPFAAQMAAEAAAKASMEHGMKTVEVNVKGPGAGREAAIRALQAAGLEITAIKDVTPIPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: SP2AB_THEPX
Sequence: MEYTNMMELNFLSKSQNESFARTVVAAFAAQLDPTIEEIADIKTAVSEAVTNCIIHGYENKIGIITIKAFISGNKITIEVIDEGKGIEDIEKAMQPLFTTRLEEERAGMGFTVMQTFMDELEVESTPGKGTLVRMTKYIGSDK
What is the function of this protein?
Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F).  Phosphorylates SpoIIAA on a serine residue.  This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
What are the official names of this protein?
Anti-sigma F factor, Stage II sporulation protein AB.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-factor family.
Protein: XYLA_STROI
Sequence: MSYQPTPEDRFTFGLWTVGWQGRDPFGDATRRALDPVETVQRLAELGAHGVTFHDDDLIPFGSSDTERESHIKRFRQALDATGMTVPMATTNLFTHPVFKDGAFTANDRDVRRYALRKTIRNIDLAAELGAKTYVAWGGREGAESGAAKDVRSALDRMKEAFDLLGEYVTSQGYVLRFAIEPKPNEPRGDILLPTVGHALAFIERLERPELYGVNPEVGHEQMAGLNFPHGIAQALWAGKLFHIDLNGQSGIKYDQDLRFGAGDLRSALWMVDLLESAGYEGPRHFDFKPPRTEDLDGVWASAAGCMRNYLILKERAAAFRADPEVQEALRASRLDQLAQPTAADGLEDLLADRAAFEDFDVEAAAARGMAFERLDQLAMDHLLGARG
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDH_CHLMU
Sequence: MFSQTVSVAVTGGTGQIAYCFLFALAHGDIFGPDTGIDLRIYDIPGTERSLSGVRMELDDGAFPLLQRVQVTTSLHDAFDDIDAAFLIGSVPRGPGMERRDLLKKNGEIFATQGKVLNTAAKREAKIFVVGNPVNTNCWIAMNHAPRLLRKNFHAMLRLDQNRMHSMLAHRAEVPLSAVSQVVVWGNHSAKQVPDFTQALIHGRPIVETIADRDWLENIMVPSVQSRGSAVIEARGKSSAASAARALAEAARSIYQPKEGEWFSSGVCSDNNPYGLPEDIIFGFPCRMLGTGEYEIVPGLPWDAFIRGKMQISLDEILQEKASVSL
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: ATPA_HISS2
Sequence: MQLNSTEISELIKKRIAQFEVINEARNTGTIVSVSDGIIRIHGLSDVMQGEMIALPGNRYAMALNLERDSVGAVVMGPYSDLAEGMEVQCTGRILEVPVGRGLLGRVVNTLGQPIDGKGEIKNDGFSPVEVIAPGVIERKSVDQPVQTGYKAVDSMVPIGRGQRELIIGDRQTGKTALAIDAIINQRDSGIKCIYVAIGQKASTIANVVRKLEEHGALQNTIVVVASASESAALQYLAPYSGCAMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERASRVSEEYVEKFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESNLFNSGIRPAVNPGISVSRVGGAAQTKVVKKLAGGIRTALAQYRELAAFAQFASDLDEATRKQLSHGQKVTELLKQKQYSPLSVAEQALVLFAVEFGYLDDVELNRIGTFETALLEYANYNYADFMAELTKTGNYDDEIKNTLKTVLDQFKANVAW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS8_VEREI
Sequence: MSMSDPIADLLTRIRNAQMVAKPTVMVPSSKVKVAIAQVLKDEGYIDGFQVKTEAGKSELEIALKYYAGRPVIERIERVSRPGLRVYKGRDAIPQVMNGLGVAIVTTPKGVMTDRKARATGVGGEVLCYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: MURC_HALH5
Sequence: MTTFHFIGIKGSGMSALAQVLHDMNYQVQGSDVEKRFFTQKPLEEKGIPIFPFQKENIKEGQQVVVSAAYSDEHEEVVAAKEQGLEIQSYPTFLGEFIQRFTSIAVTGSHGKTSTTGLLSHVLGSHCPTSFLIGDGTGKGAADSHYFVFEACEYRRHFLNYRPDYCIMTNIDFDHPDYFDDINDVFSAFQEMAMQVKKAIVACGDDEQLQGIHANVPVVYYGFNEDNDFQARNIEVTSEGTHFQVFVRNNHYGDFTIPRFGKHNVLNSLAVIALCHYENIPVEVLARELKTFEGVKRRFTEKTLGGQILIDDYAHHPTEISATIEAAKQKYPDRPVVAIFQPHTFSRTKAFLHEFAEALKQADHVYLCDIFGSARENKGSLSIEDLQALIPGAHLLSENDLAPLQDHRSGVLLFMGAGDIQKFQQAYEHVLTT
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
Protein: BYST_MONBE
Sequence: MSAKRNTKLRHAPLEHAYVDDKSVRRNKRSKQRGRMQDDESVDAPLNEKQAQVIARQAQLQQNEEDVSDSEQTGQPVDIDVPSDDEGQADDLAQPEDAYRHFEIDEHDEVALRAFMPAEPAQRRTLADIIMEKIQGKRTEVASQVSQTGPRELNPKVIEVYQGVGQVLSRYRSGKLPKAFKIIPRLKNWEEIVYITEPENWTAASMYAATRLFASNLKEKMAQRFYNLILLPRVRDDIAEYKRLNFHLYQAIKKAIFKPGAFFKGFLLPLCEAGDCTLREAVIIGGILVRKSIPVLHSSAAMLKMAEMPYSGATSIFLRVLLDKKYSLPFRVVDAVVAHFYRFNADHRQLPVLWHQCLLVFVQRYKEDITSEQKRALLDVLRSHNHYAITPEIRRELVQSKSRDREMPLEESSR
What is the function of this protein?
Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits.
What are the official names of this protein?
Bystin.
What is the protein family that this protein belongs to?
Belongs to the bystin family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RL5_SYNS3
Sequence: MSLKQRYRETIQPKLLKDLSLSNIHEVPKVLKVTVNRGLGEAATNAKSLEASVNELAQITGQKVVITRAKKAIAAFKIRQGMPIGCAVTLRGDRMYAFLERFINLALPRIRDFRGVSPKSFDGRGNYTVGVREQIIFPEISFDKIDAIRGMDITIVTSARTDEEGRALLREMGMPFRSN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: RISB_ECOHS
Sequence: MNIIEANVATPDARVAITIARFNNFINDSLLEGAIDALKRIGQVKDENITVVWVPGAYELPLAAGALAKTGKYDAVIALGTVIRGGTAHFEYVAGGASNGLAHVAQDSEIPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVLKAIKA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: KC1A_XENLA
Sequence: MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQAASSSGQGQQAQTPTGKQTDKSKSNMKGF
What is the function of this protein?
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates.  It can phosphorylate a large number of proteins.  Participates in Wnt signaling.  May play a role in segregating chromosomes during mitosis.  May play a role in keratin cytoskeleton disassembly (By similarity) (PubMed:9022677).  Phosphorylates protein custos (PubMed:25157132).
What are the official names of this protein?
Casein kinase I isoform alpha, CKI-alpha, CK1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore. Nucleus speckle. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, spindle.
Protein: ASIP_TRAFR
Sequence: MDVTRLLLATLLVFLCFFTVYSHLPPEEKLRDDRSLRSNSSVNLLDFPSVSIVALNKKSKQISRKEAEKKRSSKKEASMKKVAQPRTPLSAPCVATRDSCKPPAPACCDPCASCQCRFFRSACSCRVLSLNC
What is the function of this protein?
Involved in the regulation of melanogenesis.  The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity).
What are the official names of this protein?
Agouti-signaling protein, ASP, Agouti switch protein.
What are the subcellular locations of this protein?
Secreted.
Protein: SYT10_PONAB
Sequence: MSFHKEDGVNSLCQKALHIVTELCFAGQVEWEKCSGIFPRDRGSQGGSSTDISVSLLAVVVSFCGLALLVVSLFVFWKLCWPCWKSKPVTSNITTLPQSISSAPTEVFETEEKKEIKENEKPAMKAIEPAIKISHTSPDIPAEVQTALKEHLIKHARVQRQITEPTSSSRHNSFRRHLPRQMQVSSVDFSMGTEPVLQRGETTTSIGRIKPELYKQKSVDSEGNQKEDVKICGKLNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDRKKKFQTRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILDNLFEVSDLSREATVWKDIHCATTESIDLGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLDAEGLGRDHWNEMLAYHRKPITHWHPLLELPGRATSFDSQGSCPSPKPPSTP
What is the function of this protein?
Ca(2+) sensor specifically required for the Ca(2+)-dependent exocytosis of secretory vesicles containing IGF1 in neurons of the olfactory bulb.  Exocytosis of IGF1 is required for sensory perception of smell.  Not involved in Ca(2+)-dependent synaptic vesicle exocytosis (By similarity).  Acts through Ca(2+) and phospholipid binding to the C2 domain: Ca(2+) induces binding of the C2-domains to phospholipid membranes and to assembled SNARE-complexes; both actions contribute to triggering exocytosis (By similarity).
What are the official names of this protein?
Synaptotagmin-10, Synaptotagmin X, SytX.
What is the protein family that this protein belongs to?
Belongs to the synaptotagmin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle membrane; Single-pass membrane protein. Note=Localizes to neuronal vesicles containing IGF1 that are not enriched at synapses. Does not colocalize with synaptic vesicles or with the Golgi apparatus.
Protein: RPOY_ALKCK
Sequence: MIFKVYYQEDAAQMPVRERTKSLYIEGESEADVRLKLAKQNFNIEYVTAVTGAYLEYEQANSDFKVVNI
What is the function of this protein?
A non-essential component of RNA polymerase (RNAP).
What are the official names of this protein?
DNA-directed RNA polymerase subunit epsilon, RNAP epsilon subunit, RNA polymerase epsilon subunit, Transcriptase subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit epsilon family.
Protein: CBHC_ASPFC
Sequence: MKHLASSIALTLLLPAVQAQQTVWGQCGGQGWSGPTSCVAGAACSTLNPYYAQCIPGATATSTTLTTTTAATTTSQTTTKPTTTGPTTSAPTVTASGNPFSGYQLYANPYYSSEVHTLAMPSLPSSLQPKASAVAEVPSFVWLDVAAKVPTMGTYLADIQAKNKAGANPPIAGIFVVYDLPDRDCAALASNGEYSIANNGVANYKAYIDAIRAQLVKYSDVHTILVIEPDSLANLVTNLNVAKCANAQSAYLECVDYALKQLNLPNVAMYLDAGHAGWLGWPANLGPAATLFAKVYTDAGSPAAVRGLATNVANYNAWSLSTCPSYTQGDPNCDEKKYINAMAPLLKEAGFDAHFIMDTSRNGVQPTKQNAWGDWCNVIGTGFGVRPSTNTGDPLQDAFVWIKPGGESDGTSNSTSPRYDAHCGYSDALQPAPEAGTWFQAYFEQLLTNANPSF
What is the function of this protein?
The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose.
What are the official names of this protein?
Probable 1,4-beta-D-glucan cellobiohydrolase C, Beta-glucancellobiohydrolase C, Exocellobiohydrolase C, Exoglucanase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 6 (cellulase B) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS18_STRPQ
Sequence: MAQQRRGGFKRRKKVDFIAANKIEYVDYKDTELLSRFVSERGKILPRRVTGTSAKNQRKVTTAIKRARVMALMPYVNED
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: GATB_ZYMMO
Sequence: MEKYILEGATGSWEIVVGLEVHAQVISKSKLFSGAATAFGAEPNSQVSLIDAAMPGMLPVVNRECIRQAVRTGLAIGAVINRVSKFDRKNYFYADLPQGYQISQLYHPIVGEGSLLIDVDGEEREIGIERIHVEQDAGKLMHDQHPDKSYVDLNRAGIALMEIVSKPDIRSPAEAGAYIRKLRAILRYVGSCDGNMEEGSMRADVNVSVRKAGEPFGTRCEIKNVNSVRFVQAAIEYEARRQIEVIEDGGEIIQETRLFDHDKGETRSLRSKEDAHDYRYFPDPDLLPLELPESFIDECRESLPELPDTKRQRYITQLNLTPYTASVITADHETAAWFEAMLEYFKAPDAKIATAAANWLTSDLFGALKKLGRDITDSPVSPKQGAELVGLVADGTLSGSLAKQVFEIMLESGQDPAVIVEERGLKQTSDTGAIEEVINKILADNQDKVEQYRSGKDKLFGFFVGQTMRAMGGKANPAVVNEILKKLLSA
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: NECA1_PONAB
Sequence: MEDSQETSPSSNNSSEELSSALHLSKGMSIFLDILRRADKNDDGKLSFEEFKAYFADGVLSGEELHELFHTIDTHNTNNLDTEELCEYFSQHLGEYENVLAALEDLNLSILKAMGKTKKDYQEASNLEQFVTRFLLKETLNQLQSLQNSLECAMETTEEQTRQERQGPAKPEVLSIQWPGKRSSRRVQRHNSFSPNSPQFNVSGPGLLEEDNQWMTQINRLQKLIDRLEKKDLKLEPLEEEIIEGNTKSHIMLVQRQMSVIEEDLEEFQLALKHYVESASSQSGCLRISIQKLSNESRYMIYEFWENSSVWNSHLQTNYSKTFQRSNVDFLETPELTSTMLVPASWWILNNN
What are the official names of this protein?
N-terminal EF-hand calcium-binding protein 1, EF-hand calcium-binding protein 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOCS3_DROGR
Sequence: MIAARGAPEIEKAKLRLEIAELQAVLNAKEQQLLELQSTISTGASNGGEPESKQDHQKLSNDDIARYSRQLILPDFGIGGQLKLKNSAVLIVGIGGLGCPAAQYLAGAGCGSLGLVDYDQVERSNLHRQTLHTVARCGLSKAESARIALLELNPHCHITCHASLLNRFNAMDIMHGYDVVLDCSDNVATRYLLNDACVMLGKPLVSGSALKLDGQITVYNYGTQGPCYRCIFPVPPPPEAVTNCGDGGVLGAVTGTIGAMQALEAIKLIVGLGDVLAGRLLIFDGSSCQFRNIRIRSKRANCHVCSDQPLITQLIDYEVFCGMHATDKDNPLQLLEPEQRITVVDYQKSLQDKPHLLLDVRAQAEFEICQLPQAINVPLAQILDGSYLQQLDAQFKSSGFPIVVVCRRGNDSQIAVQHMKNQFPEHFIRDLKGGLHAWTNQIDENFPIY
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Also essential during biosynthesis of the molybdenum cofactor.  Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A.  Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus.  The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A.  Subsequently, a transient disulfide bond is formed.  Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.
What are the official names of this protein?
Adenylyltransferase and sulfurtransferase MOCS3, Molybdenum cofactor synthesis protein 3, Ubiquitin activating enzyme 4.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYD_STAAC
Sequence: MSKRTTYCGLVTEAFLGQEITLKGWVNNRRDLGGLIFVDLRDREGIVQVVFNPAFSEEALKIAETVRSEYVVEVQGTVTKRDPETVNPKIKTGQVEVQVTNIKVINKSETPPFSINEENVNVDENIRLKYRYLDLRRQELAQTFKMRHQITRSIRQYLDDEGFFDIETPVLTKSTPEGARDYLVPSRVHDGEFYALPQSPQLFKQLLMISGFDKYYQIVKCFRDEDLRADRQPEFTQVDIEMSFVDQEDVMQMGEEMLKKVVKEVKGVEINGAFPRMTYKEAMRRYGSDKPDTRFEMELIDVSQLGRDMDFKVFKDTVENDGEIKAIVAKGAAEQYTRKDMDALTEFVNIYGAKGLAWVKVVEDGLTGPIGRFFETENVETLLTLTGAEAGDLVMFVADKPNVVAQSLGALRVKLAKELGLIDETKLNFLWVTDWPLLEYDEDAKRYVAAHHPFTSPKEADIAKLGTAPEEAEANAYDIVLNGYELGGGSIRIHDGELQEKMFEVLGFTKEQAQEQFGFLLDAFKYGAPPHGGIALGLDRLVMLLTNRTNLRDTIAFPKTASATCLLTNAPGEVSDKQLEELSLRIRH
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VMA21_YEAS1
Sequence: MAVDVPRAVINKLMLFTAAMVVLPVLTFFIIQQFTPNTLISGGLAAAMANVVLIVYIVVAFREDTEDHKVDGNKKED
What is the function of this protein?
Functions with VOA1 in assembly of the integral membrane sector (also called V0 sector) of the V-ATPase in the endoplasmic reticulum.  Escorts the assembled V0 sector in COPII vesicles.  Also required for normal packaging of the SNARE BOS1 and possibly the ER to Golgi transport receptor ERV29.
What are the official names of this protein?
Vacuolar ATPase assembly integral membrane protein VMA21.
What is the protein family that this protein belongs to?
Belongs to the VMA21 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein.
Protein: RIMK_XYLFM
Sequence: MKLAILSRNSKLYSTRRLVEVARMRGHTVRILDPLRCYMRIVVGDFSMHYKGKPIDGYHAVIPRIGVSVTHYATAVLRQFELMGTYSPNPSDAILRSRDKLRAHQLLAAQGIDMPMTVFGDNPDDTQDLLSMLGPPPHVVKLNEGAQGKGVILSEKNSASRGLVEALRGLYANFLVQEFISEADSADLRCFVVGNQVVATMRRQAADGDFRSNLHLGGSATAATASEEEQEVAVRSAHALGLTVAGVDLIRSRRGPLVLEVNPTPGLEGIEATSGTNVAIKIVHHVEEMLATICSSNICQP
What are the official names of this protein?
Probable alpha-L-glutamate ligase.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: SOTB_SALHS
Sequence: MTINPVSRKVAWLRVVTLAIAAFIFNTTEFVPVGLLSDIAESFHMQTAQVGIMLTIYAWVVAVMSLPFMLLTSQMERRKLLICLFVLFIASHVLSFLAWNFTVLVISRIGIAFAHAIFWSITASLAIRLAPAGKRAQALSLIATGTALAMVLGLPIGRVVGQYFGWRTTFFAIGMGALITLLCLIKLLPKLPSEHSGSLKSLPLLFRRPALMSLYVLTVVVVTAHYTAYSYIEPFVQNVAGLSANFATVLLLILGGAGIIGSLVFGKLGNRHASSLVSIAIALLVVCLLLLLPAADSEAHLAILSIFWGIAIMVIGLGMQVKVLALAPDATDVAMALFSGIFNIGIGAGALVGNQVSLHWSMSAIGYIGAIPACAALVWAVLIFRKWPVTLEEQPH
What is the function of this protein?
Involved in the efflux of sugars.  The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites.
What are the official names of this protein?
Probable sugar efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.