PharMolix/UniProtQA huggingface dataset:
Protein: NODD2_RHILP
Sequence: MRFKGLDLNLLVALDALTTERNLTAAARSINLSQPAMSAAIGRLRDYFRDELFTMNGRELRLTPRAEGLASAVRETLLQVQCSIISWEPFNPSKSDRCFRIVLSDFMMLIYFNKIIERVAREAPAVSFELLPLDSDPYEMLSRGDVDFLIVPEFFLSGAHPSAKLFTEKFVCVACSTNVDLPSALTIEQYVSTGHVAAAFGRFLKPSVEGWFLLENGIQRRVEVVVQGFSLIPPVLRGTNRIANLPLRLVEHYESTFPLRIINLPLPLPVFTEAVQWPALHNADPGSIWFREILVEEASRMMSSNAPKIHGLLQQSGS
What is the function of this protein?
NodD regulates the expression of the nodABCFE genes which encode other nodulation proteins.  NodD is also a negative regulator of its own expression.  Binds flavonoids as inducers.
What are the official names of this protein?
Nodulation protein D 2.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: PESC_DROGR
Sequence: MRRPKKYESGEATQYISRRAALRKLQLSLNDFRRLCILKGVYPREPKHRRRAQKGSSEIKILYHTKDIRFLLHEPIVWTLRDYKIFAKKSGRDRAIKDFRNLKRRLALFPEIKLDHIVKERYPTFIDALKDLDDCLTLLFLFSTFPSLHLIPREQSNLCRRLTIEFLHYVIASKSLRKVFISIKGYYFQAEIKGQKINWIVPHYYPFKPQSRQEVDFKVMSIFVEFYTIMLGFTNFRLYHGLNLAYPPQFPSGVLQDNDETLKDESSFVSERIAALNFELLRTDKLQEDEEEPDIDMELLEQDGDSKRIIKMKQDAQEITRLRTLFKGLKFFINREVPREPLVIIIRSFGGKVSWDSTVFSGSTYDEGDESITHQIVDRPSLATQYISRDYIQPQWIFDCVNQRQLLPTNQYFIGEKLPPHLSPFVDAKRDTYIPPEERALHDPSLIETHAQSDDESEEETAAQEEEEDAVEQELLDAQLQRAYQEETAEYKKYGGADGVNEDEEDSDDEQLYEDEDESDDDEEEELDEKAQRLLEEKQKMSVQSGKVHKVNKRQVHKAEVDEHRLQARMVKPRHRNLFRKLIREKQSKEKEEWLLRKKRRNIDTDAKEQKKTAKRDARKAAAAAAAAAAQLGAK
What is the function of this protein?
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
What are the official names of this protein?
Pescadillo homolog.
What is the protein family that this protein belongs to?
Belongs to the pescadillo family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: CAVN3_RAT
Sequence: MGESALEPGPVPGAPAGGPVHAVTVVTLLEKLATMLEALRERQGGLAERQGGLAGSVRRIQSGLGALSRSHDTTSNTLAQLLAKAERVGSHADAAQERAVHRAAQVQRLEANHGLLVARGKLHVLLFKEETEIPARAFQKAPELLGPEDQLVLGPEQPEDEVGESSDEEPVESRAQRLRRTGLQKVQSLKRAFSSRKGSEAAQPTPVKPPRLGPVRNSEGPAEGQPAAQPAMEPVLPSALEPEPPQPTKEDPERPVLQIESAA
What is the function of this protein?
Regulates the traffic and/or budding of caveolae.  Plays a role in caveola formation in a tissue-specific manner.  Required for the formation of caveolae in smooth muscle but not in the lung and heart endothelial cells.  Regulates the equilibrium between cell surface-associated and cell surface-dissociated caveolae by promoting the rapid release of caveolae from the cell surface.  Plays a role in the regulation of the circadian clock.  Modulates the period length and phase of circadian gene expression and also regulates expression and interaction of the core clock components PER1/2 and CRY1/2 (By similarity).  Seems to have an immune potentiation function, especially in the glioma (PubMed:15197346).
What are the official names of this protein?
Caveolae-associated protein 3, Cavin-3, D3T-inducible gene 2 protein, DIG-2, Dithiolethione-inducible gene 2 protein, Protein kinase C delta-binding protein, Serum deprivation response factor-related gene product that binds to C-kinase.
What is the protein family that this protein belongs to?
Belongs to the CAVIN family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane, caveola. Cytoplasm, cytosol. Note=Localizes in the caveolae in a caveolin-dependent manner.
Protein: PANB_HELPJ
Sequence: MSMQTAPIKKITLSHLQAKKNQEKIIAITAYDALFAQIFDPLVDVILVGDSLNMSFFNQNDTLSASVKMMLYHTKAVCAGAKTPFIITDMPFGSYKDEKTALKNAIRVYKETQASAIKLEGGKEKAKLVKTLTDEGVIVVGHIGLMPQFVRLDGGYKIKGKNEEQQKKLLEDALSLEEAGVGLLVLEGITTPIAQTITQKIKIPTIGIGSGKDCDGQILVWSDMLGFFDSFKPKFVREYLKGKELIQNAIQQYADDVKKGNFPNELESYH
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UN04_CLOPA
Sequence: MYEVXIVVVYAAQI
What are the official names of this protein?
Unknown protein CP 4 from 2D-PAGE.
Protein: UBIE_CITBB
Sequence: MYALSEKGERIRAMFGSIAPRYDLLNRLLSLGIDRRWRRFAVKKIGLNGSGRVLDVATGTGDVALEIASQTPASVSIVGIDFTPEMIELGRVKVKDSRHCGRITLQVAPCEEIPFDDGSFDAATISFGIRNVVDRIKGLAEMHRVLKNDGKIVILEFSTPTLPVFKDLYHFYFLKVLPKIGGAFSRFSAYQYLPDSVLEFPSREVFKGMMTQVGFKDVRHFDLTGGIATVYVGTK
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: SYP_HELHP
Sequence: MRFSQLFVNTLKESPKDAVLKSHQYLIRGGFIQQIGSGIYNFLPLGKKLLDKVRFIVKEEMDKSGAQEILMGFVTPAELWRESGRYEQYGRELLRFVDRKENEFVLGPTHEEVITHIAKNTIKSYKQLPLHLYQIHSKFRDELRPRFGLMRGREFIMKDGYSFHSNYADLNREFDVMEATYKRILQRMGLEFKVVEADSGAIGGSGSKEFMVLAPCGEDTIVVCKGCEYGANIEASKRAPRTAPRPNEIKYDSNAPQAAFARFFTPDIKNIESLSAFFKVDKFWTIKAIVKKAIKANNESELVYFFVRGDDEGEETKMLNAINKHTNCYLALEDASVEEIQAAGLEVGFIGAYGLRHITQATHIYFDESLRDASNLICGANEKDYHFVGVDLSTFEGLEYADIAQSKEGDLCPKCAQELYYTKGIEVGHIFKLGDKYSRAMNAQFLDNDGKTQPLIMGCYGFGISRILPAILEQKSDDLGCIWSKEVSVFDIAIIISNTKDSVQNDFGSALYEILSACGIDVLLDERDERFGVKMKDFELLGFHSALIVGKGLNEGKVELIKREGLKKYELCATDKEILLEEILKIIA
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR7_STRMU
Sequence: MAKELIYSGKAKDILTTEDENVIIAQYKDQATALNGVKKEQIAGKGQLNNQISSLIFQKLNAAGVATHFIKKISETEQLNKKVKIIPLEVVLRNVTAGSFSKRFGVKEGIQLEKPIVEFYYKNDDLDDPFINDEHVKFLKLANDEDIAYIKAETRRINKLLSDWFHQIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDAQGHHMDKDVFRRGLGELTDVYEVVWEKLQELK
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: Y1839_PSEAE
Sequence: MRSQDLHQRLADLGAKPLHCGRIVRAWLQGRALDACTARQRAEDFLPLGVRHGLPQVAAELEGIARLHSEHPASDGSSRLLVELADRQMVESVLLPRGGLCVSTQVGCAVGCVFCMTGRSGLLRQVGSLEMVAQVVLARRRRAVKKVVFMGMGEPAHNLDNVLEAIDLLGTDGGIGHKNLVFSTVGDPRVFERLPRQRVKPALALSLHSTRAELRRQLLPKAPPLSPEELVEAGEAYARRVDYPIQYQWTLLEGINDSLEEMDGILRLLKGRFAVMNLIPYNSMDGDAYRRPSGERIVELVRYLHSRGVLTKVRNSAGQDIDGGCGQLRARATQGTAERRIPARQA
What are the official names of this protein?
Probable RNA methyltransferase PA1839.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA_METEP
Sequence: MDRIHITGGTPLNGTIPISGAKNAALPLMIASLLTGETLELINVPRLADIAALTRILGNHGVDHMVVGKRPGQTAETGQTVRLTASNVIDTTAPYELVSTMRASFWVIAPLLARFGEAKVSLPGGCAIGTRPVNLLIMALEKLGAEIEIDGGYVVAKTKNGLRGAEIVFPSVTVGGTHVALMAAALAYGTTVIDNAAREPEVVDLAECLIKMGARIEGAGTSRIVVEGVARLGGTRHEVLPDRIETGTYAMAVAMTGGDVSLVNTRTDLLASALETLASTGTEVTALPDGIRVRRNGGGISPADVTTDPFPGFPTDLQAQFMALMTLAKGQSRIRETIFENRFMHVQELARLGARIRLDGDLAVVEGVERLKGAPVMATDLRASVSLVIGALAAEGETQINRVYHLDRGFEALEAKLARCGAQIERVRA
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILI1_ORYSI
Sequence: MSSSRRSRSRRAGSSVPSSSSSSRTSISEDQIAELLSKLQALLPESQARNGAHRGSAARVLQETCSYIRSLHQEVDNLSETLAQLLASPDVTSDQAAVIRSLLM
What is the function of this protein?
Atypical and probable non DNA-binding bHLH transcription factor that acts as a positive regulator of cell elongation and plant development.  Binds the transcription repressor IBH1 and forms a heterodimer of antagonistic bHLH transcription factors that function downstream of BZR1 to mediate brassinosteroid regulation of cell elongation and lamina inclination (By similarity).
What are the official names of this protein?
Transcription factor ILI1, Basic helix-loop-helix protein 154, Protein INCREASED LEAF INCLINATION 1, bHLH transcription factor bHLH154.
What is the protein family that this protein belongs to?
Belongs to the bHLH protein family.
Protein: METN_STRPN
Sequence: MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYSGAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLMSQKTAEENVAFALKHSELSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIARALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANRVAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSLLVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAGAQEAIRQAGVQLKVLKGVQ
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RUVA_ECOL6
Sequence: MIGRLRGIIIEKQPPLVLIEVGGVGYEVHMPMTCFYELPEAGQEAIVFTHFVVREDAQLLYGFNNKQERTLFKELIKTNGVGPKLALAILSGMSAQQFVNAVEREEVGALVKLPGIGKKTAERLIVEMKDRFKGLHGDLFTPAADLVLTSPASPATDDAEQEAVAALVALGYKPQEASRMVSKIARPDASSETLIREALRAAL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: PEPA_ASPPE
Sequence: MVNTSLLAALTAYAVAVAAAPTAPQVKGFSVNQVAVPKGVYRHPAAQLAKAYGKYHATVPTQVAAAAAATGSVTTNPTSNDEEYITQVTVGDDTLGLDFDTGSADLWVFSSQTPSSERSGHDYYTPGSSAQKIDGATWSISYGDGSSASGDVYKDKVTVGGVSYDSQAVESAEKVSSEFTQDTENDGLLGLAFSSINTVQPTPQKTFFDNVKSSLSEPIFAVALKHNAPGVYDFGYTDSSKYTGSITYTDVDNSQGFWSFTADGYSIGSDSSSDSITGIADTGTTLLLLDDSIVDAYYEQVNGASYDSSQGGYVFPSSASLPDFSVTIGDYTATVPGEYISFADVGNGQTFGGIQSNSGIGFSIFGDVFLKSQYVVFDASGPRLGFAAQA
What is the function of this protein?
Secreted aspartic endopeptidase that allows assimilation of proteinaceous substrates.  The scissile peptide bond is attacked by a nucleophilic water molecule activated by two aspartic residues in the active site.  Shows a broad primary substrate specificity.  Favors hydrophobic residues at the P1 and P1' positions, but also accepts a lysine residue in the P1 position, leading to the activation of trypsinogen and chymotrypsinogen A (By similarity).  Hydrolyzes myoglobin, hemoglobin and other natural proteins.  Hydrolyzes equine myoglobin between positions 'Met-1' and 'Gly-2', 'Lys-43' and 'Phe-44', and 'Leu-70' and 'Thr-71' (PubMed:23044751).
What are the official names of this protein?
Aspergillopepsin-1, Aspartic protease pepA, Aspergillopepsin I, Aspergillopeptidase A.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PLSY_STRZP
Sequence: MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNTFRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKGGKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFGFILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYCC_HUMAN
Sequence: MADSSGQQGKGRRVQPQWSPPAGTQPCRLHLYNSLTRNKEVFIPQDGKKVTWYCCGPTVYDASHMGHARSYISFDILRRVLKDYFKFDVFYCMNITDIDDKIIKRARQNHLFEQYREKRPEAAQLLEDVQAALKPFSVKLNETTDPDKKQMLERIQHAVQLATEPLEKAVQSRLTGEEVNSCVEVLLEEAKDLLSDWLDSTLGCDVTDNSIFSKLPKFWEGDFHRDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYVSNGSVYFDTAKFASSEKHSYGKLVPEAVGDQKALQEGEGDLSISADRLSEKRSPNDFALWKASKPGEPSWPCPWGKGRPGWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSEAYFENDCWVRYFLHTGHLTIAGCKMSKSLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSNTMESALQYEKFLNEFFLNVKDILRAPVDITGQFEKWGEEEAELNKNFYDKKTAIHKALCDNVDTRTVMEEMRALVSQCNLYMAARKAVRKRPNQALLENIALYLTHMLKIFGAVEEDSSLGFPVGGPGTSLSLEATVMPYLQVLSEFREGVRKIAREQKVPEILQLSDALRDNILPELGVRFEDHEGLPTVVKLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKEYLQMAQNGSFQ
What is the function of this protein?
Catalyzes the ATP-dependent ligation of cysteine to tRNA(Cys).
What are the official names of this protein?
Cysteine--tRNA ligase, cytoplasmic, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPS_STAA3
Sequence: MELQLAIDLLNKEDAAELANKVKDYVDIVEIGTPIIYNEGLPAVKHMADNISNVKVLADMKIIDAADYEVSQAIKFGADVITILGVAEDASIKAAIEEAHKNNKQLLVDMIAVQDLEKRAKELDEMGADYIAVHTGYDLQAEGQSPLESLRTVKSVIKNSKVAVAGGIKPDTIKDIVAESPDLVIVGGGIANADDPVEAAKQCRAAIEGK
What is the function of this protein?
Catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate.
What are the official names of this protein?
3-hexulose-6-phosphate synthase, HPS, D-arabino-3-hexulose-6-phosphate formaldehyde lyase.
What is the protein family that this protein belongs to?
Belongs to the HPS/KGPDC family. HPS subfamily.
Protein: ISPE_STAHJ
Sequence: MIYETAPAKINLTLDTLFKRDDGYHEIAMIMTTVDLNDRLSFQKRKDKKIVVDIEHNYVPNDHKNLAYRAAQLMMETYDLNEGVTITIDKDIPVSAGLAGGSADAAATMRGINRLFNLDKSLHELSDLGIQIGTDIPFCIYNRTAVCKGRGEKIRFLKKPPSAWVVLAKPNLGISSADVFKALDLDDAHHVDTEMCEKAIVEGDYKQLCESLSNRLEPVSMSMHPEIKKIKNNMLQCGADGALMSGSGPTVYGLAQKESQAKKIYNAVNGCCNEVYLVRLLG
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: SSRP_GEOKA
Sequence: MPKGEGKVIAQNKKAHHDYFIEETYEAGLVLQGTEIKSIRNGRVNLKDSFAKVEKGEVFLHNMHISPYEQGNRYNHDPLRTRKLLLHRREINKLIGYTKEQGYTLVPLKLYIKNGFAKVELGVAKGKKKYDKREDMKRREAQREIERAFRERQKL
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: METE_ECOUT
Sequence: MTILNHTLGFPRVGLRRELKKAQESYWAGNSTREELLAVGRELRARHWDQQKQAGIDLLPVGDFAWYDHVLTTSLLLGNVPQRHQNNDGSVDIDTLFRIGRGRAPTGEPAAAAEMTKWFNTNYHYMVPEFVKGQQFKLTWTQLLEEVDEALALGHKVKPVLLGPITYLWLGKVKGEQFDRLSLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELPQAWLNAYKPAYDALQGQVKLLLTTYFEGVTPNLDTITALPVQGLHVDLVHGKDDVAELHKRLPSDWLLSAGLINGRNVWRADLTEKYAQIKDIVGKRDLWVASSCSLLHSPIDLSVETRLDAEVKSWFAFALQKCHELALLRDALNSGDTAALAEWSAPIQARRHSTRVHNPAVEKRLAAITAQDSQRANVYEVRAEAQRARFKLPAWPTTTIGSFPQTTEIRTLRLDFKKGNLDANNYRTGIAEHIKQAIVEQERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPIVIGDVSRPAPITVEWAKYAQSLTDKPVKGMLTGPVTILCWSFPREDVSRETIAKQIALALRDEVADLEAAGIGIIQIDEPALREGLPLRRSDWDAYLQWGVEAFRINAAVAKDDTQIHTHMCYCEFNDIMDSIAALDADVITIETSRSDMELLESFEEFDYPNEIGPGVYDIHSPNVPSVEWIEALLKKAAKRIPAERLWVNPDCGLKTRGWPETRAALANMVQAAQNLRRG
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: SYR_YERPS
Sequence: MNIQALLSDKVSQALIAAGAPADCEAQVRQSAKAQFGDYQANGVMAVAKKLGMQPRQLAERVVELLDLTGIASKIEIAGPGFINIFLDRQWVAEKVEYALTAPKLGVAPVEPQTIVVDYSAPNVAKQMHVGHLRSTIIGDAAVRTLAFLGHNVIRANHVGDWGTQFGMLIAYLEKMQNENASDMGLSDLELFYQQAKKTYDEDEEFALRARAYVVKLQSGDEYCRQMWRKLVDITMAQNQVAYDRLNVTLTKDDVMGESLYNAMLPEIVADLKAKGLAVESEGATVVYLDEYKNKDGEPMGVIIQKKDGGYLYTTTDIACAKYRYETLGADRILYYIDSRQHQHLMQAWTIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRSGGTVKLSDLLDEAVERAGKLIAEKNPDMPADELKQVINAVGIGAVKYADLSKSRTTDYIFDWDNMLALDGNTAPYMQYAYTRVVSVFRRAGVDETSLTLPLVITEDREAALATRLLQFEEIITTVAREGTPHVMCSYLYDLAGLFSSFYEHCQILNAESEEIRQSRLKLAMLTAKTLKQGLDTLGIQTVERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_BURA4
Sequence: MRLILLGAPGAGKGTQANFIKEKFGIPQISTGDMLRAAVKAGSPLGVEAKGYMDAGKLVPDALIIGLVKERLKDADCANGYLFDGFPRTIAQADAMKDAGVAIDYVLEIDVPFSEIVERMSGRRTHPASGRTYHVKFNPPKVEGKDDVTGEPLIQRDDDKEETVKKRLEVYEAQTKPLITYYGDWAKRGEENGLKAPQYRKISGLGTVDEIRERAFDALK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUS2L_MOUSE
Sequence: MIVNSLSLCYHNKLILAPMVRVGTLPMRLLALDYGADIVYCEELIDLKMLQCKRVVNEVLSTVDFVAPDDRVVFRTCEREQSRVVFQMGTSDAERALAVARLVENDVAGIDVNMGCPKEYSTKGGMGAALLSDPDKIEKILSTLVKGTHRPVTCKIRILPSLEDTLNLVKRIERTGISAIAVHGRNRDERPQHPVSCEVIRAIAETLSIPVIANGGSHDHIQQHVDIEDFRQATAASSVMVARAAMWNPSIFLKDGLRPLEEVMQKYIRYAVQYDNHYTNTKYCLCQMLREQLESPQGRLLHAAQSSQEICEAFGLGAFYEETIRELDARRADLLAKTPEAVEEPAEDTSGIIKMAIRFDRRAYPPQITPKMCLLEWCRREKLPQPVYETVQRTIDRMFCSVVTVAEQKYQSTLWDKSKKLAEQTAAIVCLRSQGLPEGRLGEESPSLNKRKREAPDQDPGGPRVQEPALPGEICKKPFVTLDSSEENLLEGC
What is the function of this protein?
Dihydrouridine synthase.  Catalyzes the NADPH-dependent synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.  Negatively regulates the activation of EIF2AK2/PKR.
What are the official names of this protein?
tRNA-dihydrouridine(20) synthase [NAD(P)+]-like, Dihydrouridine synthase 2, tRNA-dihydrouridine synthase 2-like.
What is the protein family that this protein belongs to?
Belongs to the Dus family. Dus2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum. Note=Mainly at the endoplasmic reticulum.
Protein: ERD1_YEAST
Sequence: MEKSESNSEGLYLQNILNVPPPQRFIVLIILALWIWTWILKFFLHSNLDVSQVILTRVPHDIRPGYTLQQLHRTARNFALKITRIIIPFHFATVFLFEFMNIIEGPLKNIILIVYFLPLIQCVTIFWFLLKECQIIKYCTRRCLLIESSPRSLRNTYILISDTLTSFAKPLIDFTLFTSLIFREPFTHFDLSVALLPVLVRLLQCLREYRLLHEATLLFNALKYSCNLPILFCTWRSRVYEGSINEERLHHVQRWFMLINSSYTLFWDVRMDWSLDSLTSLRSRSKSAVTLKKKMYHSAILVDFLLRFWWLWVYLSQNLKLVAADSDYIFFQGEMQYFEVIRRGIWVVFKLDAEYYIKFASK
What is the function of this protein?
Required for the retention of luminal endoplasmic reticulum proteins, affects glycoprotein processing in the Golgi apparatus.
What are the official names of this protein?
Protein ERD1.
What is the protein family that this protein belongs to?
Belongs to the ERD1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: DCUP_RICRO
Sequence: MKQIINPLKGNNDKVPIWFMRQAGRYLPEYKKVRETTKNFLDFCYDVSKATEVTLQPIKRYGFDAAIIFSDILVLPHALGWEVDFKENIGPILKQFKSQEDFKYLQINPNYKLEKVYEIIKKVKKELPSPISLIGFAGSPWTVMSYMLEGKGKQDFKTSKKFIYENKILAEELLNFITEKTADHLINQAKSGADVLKLFDSWSGVLAEEEFTKFVIEPTKKIILKVKEVFPKTPIIAFPKGAGLLYEKFIKEVPIDVLAVDQMVPLEKMKEWSDKVIVQGNLDPVVLLTNKEIIKEKTYKILQAMKGKNFIFNLGHGILPETPTENVEFLTEYVRLYEEKNSNSTF
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INSN2_ECOLI
Sequence: MKKRNFSAEFKRESAQLVVDQKYTVADAAKAMDVGLSTMTRWVKQLRDERQGKTPKASPITPEQIEIRKLRKKLQRIEMENEILKRLL
What is the function of this protein?
Involved in the transposition of the insertion sequence IS911.
What are the official names of this protein?
Putative transposase InsN for insertion sequence element IS911B.
What is the protein family that this protein belongs to?
Belongs to the transposase 8 family.