PharMolix/UniProtQA huggingface dataset:
Protein: SYL_PROM4
Sequence: MTDTSSSISRKSLRADSYQPQLIEEKWQNEWKISGLYKTREPKEDQKTFYALSMFPYPSGNLHMGHVRNYVITDVIARVHRMKGFSVLHPMGWDAFGLPAENAAIERNIQPDIWTEKNISHMRSQLDRLGLSIDWDREQTTSKSEYYKWTQSIFLKLYEAGLAYQKSATVNWDPVDKTVLANEQVDADGKSWRSGALVEKKQLKQWFLKITDYAEILLKDIDTLTEWPERVKTMQSNWIGKSVGVKINFQLLTKEKENLSVFTTRPDTLFGSTYLVLSPEDKLVDKLVDPKLINDLSNFRDYVSKLSDKERTAEGKPKNGMAIGAYAINPINQEKLPIWIADYVLSGYGTGAVMGVPAHDQRDLDFAQKYSLPIKYVIKPSGIIEKKKEVKAYSEVGVMINSGPFNGQKSDEVKSLITEKGIKENWAEKKTTYKLRDWLISRQRYWGCPIPIVHCAKCGIVPIEKENLPVFLPTNIQLSGKGNSPLKDNEWTKTQCPICKGIARRESDTMDTFICSSWYYLRFIDPNNKKNIIDKNLADRWMPVDQYVGGIEHAILHLLYARFITKVLRDKDMISIDEPFKKLLTQGMVQGITFKNPKTGKYIPPNKINNIKTPLDPSTGESLELIYEKMSKSKHNGIDPSTVIDKYGADTARMFILFKAPPEKDLEWDDADVEGQYRFLQRLWRLINESKTYNKLSLDSNENNNLNNLNQDEISLRRSVHLAIKEISNDLNEGNQFNTAISELMKLSNNMNELLGKCRISVVNESLSILIRILSPFAPHLAEEAWSTLKGKGSVHEQKWPEFDPNALKQDNYQLVIQMNGKVRGSIKIASETNKQEIEKIALNSDIAKKWLIDGSYKKVIVVLGKLVNIVY
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP_POPAL
Sequence: MPIGVPKVPFRNPGEDSSNWIDVYNRLYRERLLFLGQDIDSEISNQLIGLMVYLSTESEIKDLYLFINSPGGWVIPGIAIYDTMQFVRPDVQTVCMGLAASMGSFILVGGKITKRLAFPHARVMIHQPFAAFYEAQIGEFVLEAEELLKLREILTRVYAQRTGKPLWVVSEDMERDVFMSAAEAQVHGIVDLVAVA
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: OAR_BOMMO
Sequence: MGQAATHDANNYTSINYTEIYDVIEDEKDVCAVADEPNIPCSFGISLAVPEWEAICTAIILTMIIISTVVGNILVILSVFTYKPLRIVQNFFIVSLAVADLTVAILVLPLNVAYSILGQWVFGIYVCKMWLTCDIMCCTSSILNLCAIALDRYWAITDPINYAQKRTLERVLFMIGIVWILSLVISSPPLLGWNDWPEVFEPDTPCRLTSQPGFVIFSSSGSFYIPLVIMTVVYFEIYLATKKRLRDRAKATKISTISSGRNKYETKESDPNDQDSVSSDANPNEHQGGTRLVAENEKKHRTRKLTPKKKPKRRYWSKDDKSHNKLIIPILSNENSVTDIGENLENRNTSSESNSKETHEDNMIEITEAAPVKIQKRPKQNQTNAVYQFIEEKQRISLTRERRAARTLGIIMGVFVVCWLPFFVIYLVIPFCVSCCLSNKFINFITWLGYVNSALNPLIYTIFNMDFRRAFKKLLFIKC
What is the function of this protein?
Receptor for octopamine.  Octopamine (OA) is a neurotransmitter, neurohormone, and neuromodulator in invertebrates.  The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity).
What are the official names of this protein?
Octopamine receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYP_PSYWF
Sequence: MRASQFLFATLKETPSDADIVSSQLMLRAGLIRKLASGLYVWLPMGLKVLQKVEKIVREEMQNIGGQEVLMPMTQPAELWQESGRFEDYGPELLRFTDRHNRDFVLGPTHEEVITDLARGELRSYKQLPVTFFQIQGKFRDEIRPRFGIMRAREFTMKDAYSFHVDQASLEVTYQQMYDAYTRIFQRLGLNFRAVLADTGSIGGSASHEFHVLAGSGEDAIAFSDGSDYAANVELAEAICTDERAAPTQDKQNVSTPKIQTNEELAKFLDIPLHTTVKTLVVKGHRINEDGSEGDEQLVALVVRGDHTLNEIKAEKIAEVATPLTFATEEEMKAAGLKKGFIGVDLDMPVYVDRAAAALSDFVSGANEYDMHTTGMNWERDATITDVVDIRNVVEGDASPDGKGTLSIKRGIEVGHIFQLGDKYSKALNCTVMGEDGKPVTLMMGCYGIGVSRIIAAAIEQNHDDNGIIWAKTPDIKDSIAPFDIAIVPMKSKEDTVMQTAEALYEELKARGLNVILDDRNERPGVKFADLELIGIPHRIVVSDRNLAEDKYEYVDRRDGEKQLLSREELLAKVSL
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MENA_ARATH
Sequence: MVNFVSLCDIKYGFVPKNSTDLFVKRKIHKLPSRGDVITRLPVFGSNARENLNAKPRRNLRVRPIFCKSYGDAAKVYQEEEIPRAKLIWRAIKLPMYSVALVPLTVGASAAYLETGLFLARRYVTLLLSSILIITWLNLSNDVYDFDTGADKNKMESVVNLVGSRTGTLAAAITSLALGVSGLVWTSLNASNIRAILLLASAILCGYVYQCPPFRLSYQGLGEPLCFAAFGPFATTAFYLLLGSSSEMRHLPLSGRVLSSSVLVGFTTSLILFCSHFHQVDGDLAVGKYSPLVRLGTEKGAFVVRWTIRLLYSMLLVLGLTRILPLPCTLMCFLTLPVGNLVSSYVEKHHKDNGKIFMAKYYCVRLHALLGAALSLGLVIAR
What is the function of this protein?
Involved in the synthesis of phylloquinone (vitamin K1).  Catalyzes the transfer of a prenyl chain to 2-carboxy-1,4-naphthoquinone.
What are the official names of this protein?
2-carboxy-1,4-naphthoquinone phytyltransferase, chloroplastic, 1,4-dihydroxy-2-naphthoate phytyltransferase, 1,4-dihydroxy-2-naphthoate polyprenyltransferase, Protein ABERRANT CHLOROPLAST DEVELOPMENT 4, menA-like protein, AtMENA.
What is the protein family that this protein belongs to?
Belongs to the MenA family. Type 2 subfamily.
Protein: VILI_HUMAN
Sequence: MTKLSAQVKGSLNITTPGLQIWRIEAMQMVPVPSSTFGSFFDGDCYIILAIHKTASSLSYDIHYWIGQDSSLDEQGAAAIYTTQMDDFLKGRAVQHREVQGNESEAFRGYFKQGLVIRKGGVASGMKHVETNSYDVQRLLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESTRMERLRGMTLAKEIRDQERGGRTYVGVVDGENELASPKLMEVMNHVLGKRRELKAAVPDTVVEPALKAALKLYHVSDSEGNLVVREVATRPLTQDLLSHEDCYILDQGGLKIYVWKGKKANEQEKKGAMSHALNFIKAKQYPPSTQVEVQNDGAESAVFQQLFQKWTASNRTSGLGKTHTVGSVAKVEQVKFDATSMHVKPQVAAQQKMVDDGSGEVQVWRIENLELVPVDSKWLGHFYGGDCYLLLYTYLIGEKQHYLLYVWQGSQASQDEITASAYQAVILDQKYNGEPVQIRVPMGKEPPHLMSIFKGRMVVYQGGTSRTNNLETGPSTRLFQVQGTGANNTKAFEVPARANFLNSNDVFVLKTQSCCYLWCGKGCSGDEREMAKMVADTISRTEKQVVVEGQEPANFWMALGGKAPYANTKRLQEENLVITPRLFECSNKTGRFLATEIPDFNQDDLEEDDVFLLDVWDQVFFWIGKHANEEEKKAAATTAQEYLKTHPSGRDPETPIIVVKQGHEPPTFTGWFLAWDPFKWSNTKSYEDLKAELGNSRDWSQITAEVTSPKVDVFNANSNLSSGPLPIFPLEQLVNKPVEELPEGVDPSRKEEHLSIEDFTQAFGMTPAAFSALPRWKQQNLKKEKGLF
What is the function of this protein?
Epithelial cell-specific Ca(2+)-regulated actin-modifying protein that modulates the reorganization of microvillar actin filaments.  Plays a role in the actin nucleation, actin filament bundle assembly, actin filament capping and severing.  Binds phosphatidylinositol 4,5-bisphosphate (PIP2) and lysophosphatidic acid (LPA); binds LPA with higher affinity than PIP2.  Binding to LPA increases its phosphorylation by SRC and inhibits all actin-modifying activities.  Binding to PIP2 inhibits actin-capping and -severing activities but enhances actin-bundling activity.  Regulates the intestinal epithelial cell morphology, cell invasion, cell migration and apoptosis.  Protects against apoptosis induced by dextran sodium sulfate (DSS) in the gastrointestinal epithelium.  Appears to regulate cell death by maintaining mitochondrial integrity.  Enhances hepatocyte growth factor (HGF)-induced epithelial cell motility, chemotaxis and wound repair.  Upon S. flexneri cell infection, its actin-severing activity enhances actin-based motility of the bacteria and plays a role during the dissemination.
What are the official names of this protein?
Villin-1.
What is the protein family that this protein belongs to?
Belongs to the villin/gelsolin family.
Protein: PCDGF_HUMAN
Sequence: MGNSSGWRGPAGQRRMLFLFLLSLLDQALSEPIRYAIPEELDRGSLVGNLAKDLGFGVGDLPTRNLRVIAEKKFFTVSPENGNLLVSDRIDREEICGKKSTCVLEFEMVAEKPLNFFHVTVLIQDINDNPPTFSQNITELEISELALTGATFALESAQDPDVGVNSLQQYYLSPDPHFSLIQKENLDGSRYPELVLKAPLDREEQPHHHLVLTAVDGGEPSRSCTTQIRVIVADANDNPPVFTQDMYRVNVAENLPAGSSVLKVMAIDMDEGINAEIIYAFINIGKEVRQLFKLDSKTGELTTIGELDFEERDSYTIGVEAKDGGHHTAYCKVQIDISDENDNAPEITLASESQHIQEDAELGTAVALIKTHDLDSGFNGEILCQLKGNFPFKIVQDTKNTYRLVTDGALDREQIPEYNVTITATDKGNPPLSSSKTITLHILDVNDNVPVFHQASYTVHVAENNPPGASIAHVRASDPDLGPNGLVSYYIVASDLEPRELSSYVSVSARSGVVFAQRAFDHEQLRAFELTLQARDQGSPTLSANVSLRVLVDDRNDNAPLVLYPALGPEGSALFDMVPRSAEPGYLVTKVVAVDADSGYNAWLSYHIVQASEPGLFSLGLRTGEVRTARTLGDREAARQRLLVTVRDGGQQPLSATVMLHLIFADSLQEIQPDLSDRPTPSDPQAELQFHLVVALALISVLFLLAVILAISLRLRCSSRPATEGYFQPGVCFKTVPGVLPTYSERTLPYSYNPCAASHSSNTEFKFLNIKAENAAPQDLLCDEASWFESNDNPEMPSNSGNLQKQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.  May be involved in the establishment and maintenance of specific neuronal connections in the brain.
What are the official names of this protein?
Protocadherin gamma-B3, PCDH-gamma-B3.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: SYFA_TOLAT
Sequence: MQQLEEVVASALAKIAEATDNNALEALRVEYFGKKGVFTEQMKALAGLSPEERPAAGQLINQAKEKAQNALNERREALTTAELAKKLAAETIDVSLPGRRFENGGIHPVTRTIERIERIFGELGFSAEYGPEIEDDFHNFDALNIPGHHPARTDHDTFYFNPTLMLRTHTSGVQIRTMEKQQPPIRIIAPGRVYRNDYDQTHTPMFHQVEGLLVDENISFSNLKGILHDFLLNFFEEDLQIRFRPSYFPFTEPSAEVDVMGKNGRWLEVLGCGMVHPNVLRSVGIDPEKYSGFAFGMGVERLTMLRYGVNDLRAFFENDLRFLKQFK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1985_HAHCH
Sequence: MLITNIETIPGKNIVKHLGLVQGSTVRSKHVGRDIMAGLKNIFGGELRGYTELLEDARGEALERMKRQARGMGANAVINVRFATSSVAQGAAELFVYGTAVVME
What are the official names of this protein?
UPF0145 protein HCH_01985.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: RS8_CLOD6
Sequence: MTMTDPIADMLTRIRNANVVKHETVDVPASNMKKELARILLEEGFIRGYDVIEDGKQGIIRIQLKYGQEGERVITGLKKISKPGMRVYAANHEIPKVLNGLGISVISTSKGILTDKQARKENVGGEVICYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RL9_LACCB
Sequence: MKVIFTQDVRGKGNRGQVKEVPDGYAENFLIRKGLAKAATPQAMSALRGQQRLEEKKEAEKKTEAEAMKAKIEDDKTVVQIQSKAGEDSRLFGSIPSKQIAQALDKQYQIKVDKRKIDLKQPIRSLGFTNVTVNLFPGIDARIRVHVIEQK
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: IRAP_SALPA
Sequence: MKNLIAELLLKLAQKEEESKELVAQVEALEIIVTAMLRNMAQNEQEMLIRQVEGALEGVKPDASVPDHDTELLRQYVKKLLRHPRH
What is the function of this protein?
Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate and magnesium starvation, but also in stationary phase and during nitrogen starvation.  Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway.
What are the official names of this protein?
Anti-adapter protein IraP.
What is the protein family that this protein belongs to?
Belongs to the IraP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MB3L1_MOUSE
Sequence: MGKTSQRKQCDCENPSKPCLSTSIPLRMSSYTFKRPVTKITSHLGNEVRYYQWEETLEKPEQACWQKRLQGLQAYSSAGELLSTSDLAKTLKDLTSTDTVASASDTQATSIDITSVPTLESSSHLANMIPEAGPQILCKEFLVTEQDIINQERKVKIARERLAVALIAHKLASEMETVRGSRKANL
What is the function of this protein?
Transcriptional repressor.
What are the official names of this protein?
Methyl-CpG-binding domain protein 3-like 1, MBD3-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the MBD3L family.
What are the subcellular locations of this protein?
Nucleus. Note=Nuclear, in large foci.
Protein: PRDX1_MYOLU
Sequence: MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFSDRAEEFKKINCQVIGASVDSHFCHLAWINTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLKADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPGSDTIKPDVQKSKEYFSKQK
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.  Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2) (By similarity).  Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation (By similarity).
What are the official names of this protein?
Peroxiredoxin-1, Thioredoxin-dependent peroxiredoxin 1.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCNL1_MOUSE
Sequence: MNKLKSSQKDKVRQFMIFTQSSEKTAVSCLSQNDWKLDVATDNFFQNPELYIRESVKGSLDRKKLEQLYTRYKDPQDENKIGIDGIQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQEFMDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLDLEMAIAYWNLVLNGRFKFLDLWNKFLLEHHKRSIPKDTWNLLLDFSSMIADDMSNYDEEGAWPVLIDDFVEFARPQIAGTKSTTV
What is the function of this protein?
Part of an E3 ubiquitin ligase complex for neddylation.  Promotes neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes (By similarity).  Acts by binding to cullin-RBX1 complexes in the cytoplasm and promoting their nuclear translocation, enhancing recruitment of E2-NEDD8 (UBE2M-NEDD8) thioester to the complex, and optimizing the orientation of proteins in the complex to allow efficient transfer of NEDD8 from the E2 to the cullin substrates.  Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity (By similarity).  Acts also as an oncogene facilitating malignant transformation and carcinogenic progression (PubMed:20563250).
What are the official names of this protein?
DCN1-like protein 1, DCNL1, DCUN1 domain-containing protein 1, Defective in cullin neddylation protein 1-like protein 1, Testis-specific protein 3.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=The ubiquitinated form is localized in the cytoplasm.
Protein: ADD_CLOBK
Sequence: MNFKKLPKIELHCHLDGSLRVDTILDIAKKDNIPLPSYNKKELINYVSIMDDCNSLDEYLNKFFIPNKVMQTKENLKRIAFELLEDVAADNVKYIEVRFAPLLHVEKGLNIEEIIESVLEGIKEAEKLYDIKGNLILGCMRNMDIPSAFEVVKKGAKFIGKGVVAIDLCAGEEPHFPGKYIEVLKLAKEYGYRITIHAGEAGVGENVLEAINLLNAERIGHGIYIKDCAEAYKLVKEKNIPLEMCPTSNLHTKASESYEAHPFMDFLKDGIKVTINTDNMTVSNTTITKELEMLNKFCGLSIEDYKILYLNAVEASFASSETKEVLKSYVKEITA
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
What are the official names of this protein?
Adenosine deaminase, Adenosine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
Protein: FAXD2_DEMVE
Sequence: MAPQLLLCLILTFLWSLPEAESNVFLKSNVANRFLQRTKRANSIFEEIRPGNIERECVEEKCSKEEAREVFQDNEKTEAFWTVYVDGDQCLSNPCHYRGTCKDGIGSYTCTCLPGYEGKNCEHVVVKSCRLFNGNCWHFCKTVQNDTQCSCAEGYRLGVDGFSCIAEGDFSCGRIIKSRNKREASLPDFHFSDDYDAIDENNLVETVQSQSATLLKKSDNPSPDIRIVSGLDCKLGECPWQAVLIDEHGKAFGGGTILSPYFVLTAAHCLNQTKSIAVVVGQVDISRKETRHLLHVDKAYMHSKYVRATYDHDIAILRLRTPIQFSENVVPACLPTADFADEVLMKQDFGIVSGFGRLHERGSTSDILKVIRVPYVDRYTCMLSSNYRITPSMFCAGYGNQPQDACQGDSGGPHITAYGDTHFITGIISWGEGCGRKGKYGIYTKVSNFIPWIKTIMRRNQPSTESSTGRL
What is the function of this protein?
Snake prothrombin activator that attacks the hemostatic system of prey.  This protein is functionally similar to blood coagulation factor Xa (By similarity).
What are the official names of this protein?
Venom prothrombin activator vestarin-D2, vPA, Venom coagulation factor Xa-like protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: S10A6_CHICK
Sequence: MAAPLDQAIGLLVATFHKYSGKEGDKNSLSKGELKELIQKELTIGPKLKDAEIAGLMEDLDRNKDQEVNFQEYVTFLGALAMIYNEALLQYK
What is the function of this protein?
May function as calcium sensor and modulator, contributing to cellular calcium signaling.  May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility.  Binds 2 calcium ions.  Calcium binding is cooperative (By similarity).
What are the official names of this protein?
Protein S100-A6, Calcyclin, S100 calcium-binding protein A6.
What is the protein family that this protein belongs to?
Belongs to the S-100 family.
Protein: POP5_MOUSE
Sequence: MVRFKHRYLLCELVSEDARCRLSLDDRVLGGLVRDTIARVHGAFGAAACSVGFAVRYLNAYTGVVLLRCRKDFYQLVWSALPFITYLENKGHRYPCFFNTLHVGGTIRTCQKFLIQYNRRQLLILLQNCTDEGEREAIKKSVSRSCLLDREPVEELSDSAGEEVAEAME
What is the function of this protein?
Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.  Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences.
What are the official names of this protein?
Ribonuclease P/MRP protein subunit POP5.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: Y520_BURM1
Sequence: MRIVLITGISGSGKSVALNALEDAGYYCVDNLPPHVLPELARYLDEAGQRRLAVAIDARSSASLDEMPGLIRSLSREHDLRVLFLNASTQALIQRFSETRRRHPLSGSPSHDANVGLLSSLEEAIERERELVAPLAEFGHQIDTSTLRANVLRTWVKRFIEQNSNDLMLMFESFGFKRGVPLDADLMFDVRALPNPYYDHELRPLTGLDQPVIAFLDALPIVHQMIDDIHAFLMKWLPHFREDNRSYLTVAIGCTGGQHRSVFIAETLAARFASAANVIVRHRDAPVDVDASSRLVTEVDRP
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Bmul_0520/BMULJ_02739.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: GLB_APLKU
Sequence: MSLSAAEADLVGKSWAPVYANKDANGDAFLLSLFEKFPNNANYFADFKGKSIADIKASPKLRDVSSRIFTRLNEFVNNAADAGKMSAMLSQFASEHVGFGVGSAQFENVRSMFPAFVASLSAPPADDAWNKLFGLIVAALKAAGK
What are the official names of this protein?
Globin, Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: IF6_THEAC
Sequence: MIRKTSVLRSNFIGIYAKAWDDVAFITMMADEKTVADFQEVLQVDVRRISIDNSSLIGTMMVMNSNGLIVPYGSEITGLGDLDGRNVLQLKDKINAIGNDIIANDHGAIIHKNFSNRSRKEIEDTLGVETIRTTIGNILTVGSAGILTSKGMLVNPETDDDELEFLRDFFKVSVKSGTANFGSIYVGASIVANSKGVLVGKDTTPIEMDRIDDVLS
What is the function of this protein?
Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.
What are the official names of this protein?
Translation initiation factor 6, aIF-6.
What is the protein family that this protein belongs to?
Belongs to the eIF-6 family.
Protein: RNH2_HAES1
Sequence: MTNAFVYPNVEFIAGVDEVGRGPLVGAVVTAAVILDPHNPIEGLKDSKKLSEKKRLLLAEEIKQKALAWSLGRAEPAEIDKLNILHATMLAMQRAVENLKIQPHFVLVDGNRIPQLPMSAQAVIKGDSLVAEISAASILAKVARDQEMIELDRRYPEYAFAQHKGYPTKLHLERLAQFGVLPEYRRSFAPVKKLLSTLLSKNHEYVFKIQK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS8_CHESB
Sequence: MTALDHPQPRPGIKNIAAYVPGRESAPGVEKIWKLSSNETPLGPSPAALEAVREASQHLEIYPDGSASKLRDAIAKAHGLNPANILCSNGSDELLALLAQTYLMPGDEGIYTEHGFLVYRIQILAAGATPVVAREKDERADVDAILAAVTERTKIVFLANPNNPTGTYLPMEEVKRLRSGLPRKVLLVLDAAYAEYVRRNDYEAGVELVSSNDNVVMTRTFSKIHGLAGLRIGWMYAPIHVVDAVNRVRGPFNVNAIAIEAGTAATHDKAHVERAVEHNETWRTWLAQELEKLGLRVTPSVANFLLIHFPENGSKTAEEADAFLTARGYILRRVTGYGFPHALRLTVGTEEANRGVIAALAEFLER
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: NUON_PAESJ
Sequence: MTEFVPLTWHDTLYLAPELILAAMFLILIVTDLILPGRTNRAIIGWLSLAGLLLSLAAVIWRMIDMNPSGVSAAEAAEAGKAISLLGASYRVDDYGNLLKIIFLIGTSLVVLLGLGSTQKDDAVTDKAEFYYLLLPAAAGAMIMASSGNLVTLYIGLELLSITTYVLVGLRKRSSLSAEAAFKYVVTGGIASAFVLFGMSYLYGVTGSVSLADFPTALPQAFTDYKALVYVGFFFLIAGFGIKIAAAPFHIWAADVYQGAPTPVSAFLAVIAKGAALAAVFRFLYSSAFFLTGGPGKQAGDDVFFALLVIAAAAMIAGTVSALRQKQVKRLLALSGVANAGYLLVPIAISVTIIHSNNFSEFVFYLVAYLLMNVGAFAVVTVIARAAGHEELKGFSGLYYRAPWTAAAMLIFILSFSGLPVTAGFFGKLFILLGAASVKAYWLVAIMVVSTVISYYFYFGIIRQMFMRSNGEEEDRIHVPAVTGTVIWICAAATVALGVLPGPLMKWIDAVFTIQADLFVR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CT53_CONTS
Sequence: MLCLPVFIILLLLASPAAPNPLERRIQSDLIRTALEDADMKTPKGVLSGIMSNLGTVGNMVGGFCCTVYSGCCSEK
What are the official names of this protein?
Conotoxin TsMLCL-03.
What is the protein family that this protein belongs to?
Belongs to the conotoxin T superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ISPF_THET2
Sequence: MRIGYGEDSHRLEEGRPLYLCGLLIPSPVGALAHSDGDAALHALTDALLSAYGLGDIGLLFPDTDPRWRGERSEVFLREALRLVEARGARLLQASLVLTLDRPKLGPHRKALVDSLARLLRLPQDRIGLTFKTSEGLAPSHVQARAVVLLDG
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: NUOB_BRASB
Sequence: MSPNPSSTGPVIAPAPKGILDPATGRPIGANDPYFLEVRHELSDKGFFVATADDLITWARTGSLMWMTFGLACCAVEMMQVSMPRYDVERFGFAPRASPRQSDVMIVAGTLTNKMAPALRKVYDQMPEPRYVISMGSCANGGGYYHYSYSVVRGCDRIVPIDIYVPGCPPTAEALLYGVLLLQKKIRRTGTIER
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.