PharMolix/UniProtQA huggingface dataset:
Protein: C56D2_BOVIN
Sequence: MALSVETESHIYRALRTVSGAAAHLVALGFTIFVAVLARPGSSLFSWHPVLMSLAFSFLMTEALLVFSPESSLLRSLSRKGRARCHWVLQLLALLCALLGLGLVILHKEQLGKAHLATWHGRAGLLAVLWAGLQCSGGVGLLYPKLLPRWPLAKLKLYHATSGLVGYLLGGASLLLGMCSLWFTATVTGGVWYLAVLCPVITSLVIMNQVSNAYLYRKRIQP
What is the function of this protein?
Transmembrane reductase that may use ascorbate as an electron donor in the cytoplasm and transfer electrons across endoplasmic reticulum membranes to reduce monodehydro-L-ascorbate radical and iron cations Fe(3+) in the lumen of that compartment.
What are the official names of this protein?
Transmembrane reductase CYB561D2, Cytochrome b561 domain-containing protein 2.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Protein: PIGR_RABIT
Sequence: MALFLLTCLLAVFSAATAQSSLLGPSSIFGPGEVNVLEGDSVSITCYYPTTSVTRHSRKFWCREEESGRCVTLASTGYTSQEYSGRGKLTDFPDKGEFVVTVDQLTQNDSGSYKCGVGVNGRGLDFGVNVLVSQKPEPDDVVYKQYESYTVTITCPFTYATRQLKKSFYKVEDGELVLIIDSSSKEAKDPRYKGRITLQIQSTTAKEFTVTIKHLQLNDAGQYVCQSGSDPTAEEQNVDLRLLTPGLLYGNLGGSVTFECALDSEDANAVASLRQVRGGNVVIDSQGTIDPAFEGRILFTKAENGHFSVVIAGLRKEDTGNYLCGVQSNGQSGDGPTQLRQLFVNEEIDVSRSPPVLKGFPGGSVTIRCPYNPKRSDSHLQLYLWEGSQTRHLLVDSGEGLVQKDYTGRLALFEEPGNGTFSVVLNQLTAEDEGFYWCVSDDDESLTTSVKLQIVDGEPSPTIDKFTAVQGEPVEITCHFPCKYFSSEKYWCKWNDHGCEDLPTKLSSSGDLVKCNNNLVLTLTLDSVSEDDEGWYWCGAKDGHEFEEVAAVRVELTEPAKVAVEPAKVPVDPAKAAPAPAEEKAKARCPVPRRRQWYPLSRKLRTSCPEPRLLAEEVAVQSAEDPASGSRASVDASSASGQSGSAKVLISTLVPLGLVLAAGAMAVAIARARHRRNVDRVSIGSYRTDISMSDLENSREFGAIDNPSACPDARETALGGKDELATATESTVEIEEPKKAKRSSKEEADLAYSAFLLQSNTIAAEHQDGPKEA
What is the function of this protein?
Through its N-linked glycans ensures anchoring of secretory IgA (sIgA) molecules to mucus lining the epithelial surface to neutralize extracellular pathogens.  On its own (free form) may act as a non-specific microbial scavenger to prevent pathogen interaction with epithelial cells.
What are the official names of this protein?
Polymeric immunoglobulin receptor, PIgR, Poly-Ig receptor.
What are the subcellular locations of this protein?
[Polymeric immunoglobulin receptor]: Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Secretory component]: Secreted.
Protein: SYI_DESVV
Sequence: MSDYKKTLQLPETKFPMKANLTQREPEMLRKWEKDDAYGAMVRASGQQGTYVLHDGPPYANGNIHMGHALNKILKDIIVKSRNLQGFKAEYVPGWDCHGLPIELKVEHELGEKKRTMPAHAVRKRCRQYAEKYLDIQRKEFKRLGVFGAWDKPYVTMHPSYEAATARELGNFAAKGGLVRSKKPIYWCCSCQTALAEAEVEYHDHTSPSVHVRFPLRDPRVAEVLPGVDPAHAYIVIWTTTPWTLPDNMAVAVHPDFDYVVVRHGGDFHIVAEGLLEACLKAFKWDEHEVVARIGGRALEGLKATHPFYDRPSPIVLADYVTLESGTGCVHTAPGHGREDYETGLRYGLDIYSPLTDEGRYLDCVEFFAGMTIFEANPKVIEKLREVGNLLAEGRITHSYPHCWRCKKPVIFRATTQWFIAMERNDLRQKALDAIRDDVRWIPSWGQERIHNMIEFRPDWCISRQRMWGVPIVALLCEDCGEAWNDADWMRDIAERFAKHATGCDYWYETDLSDIVPAGLRCPKCGGDHWKKETDILDVWFDSGTSFAAVVEQREECGFPADLYLEGSDQHRGWFHSSLLASIGTRGVPPYRSVLTHGYVVDGDGRKMSKSVGNVVAPQEIIDKHGAEVLRLWVASVDYREDIRISEEILNRLVDAYRRIRNTCRYLLGNISDLTPETMVPFEAMDPLDRFALDLASRAHERIQDAYTEYEFHKVFHTLHNLCVTDLSAFYLDILKDRLYSSAADSHARRSAQTALYRILMLMVRDMAPVLSFTAEEVFGYVPAALRPDVISVFALPATDAPAFTLDTTSRAAWEKLLAVRSETTKAIEPLRKSGEVGHSLDTHVTLFADPSLKATLEGLGSDLRAMFIVSRLEVMNLADAPADAWTSEELPELRVAVRKAEGEKCERCWIISADLGTDAAHPTLCPRCTAVLTGTGA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATB_MYCS5
Sequence: MINFETVIGIEIHIELKTKTKMFSPVEINFNAESNTKANQIDLGYPGTLPQVNKKAVKYAIMLAKALNMQIDSNLRFDRKHYFYPDLPKGYQITQFYHPIGREGQIKLNNNGKEFEVNIERIHLEEDTARQHHKDNYSQLDYNRAGIPLIEIVTHPVLRSSDEACLYVDAIRKVVQTLEISEGRLEIGSLRADINISIRPLGSKSFSNKVEIKNLNSLKNIKLAIEEEIALQRAKFFANEEVLQQTKKIDEKTLKLQVLRTKTSTIDYRYFPEPNIPFIKLSKKFISSVKLKELPWEKEARYKSYNLNSIYLNSLLDDIHLANYFDSISYPDKDKLSKIFFAEVVSLANSKEMKAYHLNIDPENITKAINLLDEEVISGKSLKKLIPLLVNFKSDIKKLVKQNSLEQISDPNLISNIIKEIIKTNSELVKEYPTRQEKVLKFVLGKLMKDTGGQVNPTVANEIAIKSLDEVFK
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: OBG_FRATM
Sequence: MRFVDEVVIKLQAGKGGNGCVSFRREKYVPRGGPDGGDGGNGGSIYLKADENVNTLIDYRYKREYYAENGRPGEGRNCYGKAGEDLYLVVPVGTSVFDIDTNKKIGEVLQHGQTFKLVSGGKRGIGNTHFKSSTNQAPRKFTLGEEGEYKEVRLELNLLADVALLGLPNAGKSTLIRSVSEATPKVADYPFTTMYPHLGVVKVGVDSFVMADIPGVIEGAAEGAGLGLRFLKHLTRARCVLHVVDICPFSESDPVENYFAVEKELEKYSQELFDKPRFLVINKIDLLADKVEQKCQEFVEQIGYQGNYYTISAAMKKGTDELAKKLNEFLQKQE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS21_HAEDU
Sequence: MPVIKVRENESFDVALRRFKRSCEKAGLLAEVRAREFYEKPTTVRKREKASLAKRHAKRNARENARNTRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: PGCB_MOUSE
Sequence: MIPLLLSLLAALVLTQAPAALADDLKEDSSEDRAFRVRIGATQLRGVLGGALAIPCHVHHLRPPHSRRAAPGFPRVKWTFLSGDREVEVLVARGLRVKVNEAYRFRVALPAYPASLTDVSLVLSELRPNDSGVYRCEVQHGIDDSSDAVEVKVKGVVFLYREGSARYAFSFAGAQEACARIGARIATPEQLYAAYLGGYEQCDAGWLSDQTVRYPIQNPREACSGDMDGYPGVRNYGVVGPDDLYDVYCYAEDLNGELFLGAPPSKLTWEEARDYCLERGAQIASTGQLYAAWNGGLDRCSPGWLADGSVRYPIITPSQRCGGGLPGVKTLFLFPNQTGFPSKQNRFNVYCFRDSAHPSASSEASSPASDGLEAIVTVTEKLEELQLPQEAMESESRGAIYSIPISEDGGGGSSTPEDPAEAPRTPLESETQSIAPPTESSEEEGVALEEEERFKDLEALEEEKEQEDLWVWPRELSSPLPTGSETEHSLSQVSPPAQAVLQLGASPSPGPPRVRGPPAETLLPPREGSPTSTPGGAREVGGETGSPELSGVPRESEEAGSSSLEDGPSLLPATWAPVGPRELETPSEEKSGRTVLAGTSVQAQPVLPTDSASHGGVAVAPSSGDCIPSPCHNGGTCLEEKEGFRCLCLPGYGGDLCDVGLHFCSPGWEAFQGACYKHFSTRRSWEEAESQCRALGAHLTSICTPEEQDFVNDRYREYQWIGLNDRTIEGDFLWSDGAPLLYENWNPGQPDSYFLSGENCVVMVWHDQGQWSDVPCNYHLSYTCKMGLVSCGPPPQLPLAQIFGRPRLRYAVDTVLRYRCRDGLAQRNLPLIRCQENGLWEAPQISCVPRRPGRALRSMDAPEGPRGQLSRHRKAPLTPPSSL
What is the function of this protein?
May play a role in the terminally differentiating and the adult nervous system during postnatal development.  Could stabilize interactions between hyaluronan (HA) and brain proteoglycans.
What are the official names of this protein?
Brevican core protein.
What is the protein family that this protein belongs to?
Belongs to the aggrecan/versican proteoglycan family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: LIPA_STAAS
Sequence: MATKNEEILRKPDWLKIKLNTNENYTGLKKMMREKNLNTVCEEAKCPNIHECWGARRTATFMILGAVCTRACRFCAVKTGLPNELDLNEPERVAESVELMNLKHVVITAVARDDLRDAGSNVYAETVRKVRERNPFTTIEILPSDMGGDYDALETLMASRPDILNHNIETVRRLTPRVRARATYDRTLEFLRRSKELQPDIPTKSSIMVGLGETIEEIYETMDDLRANDVDILTIGQYLQPSRKHLKVQKYYTPLEFGKLRKVAMDKGFKHCQAGPLVRSSYHADEQVNEAAKEKQRQGEAQLNS
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLY_BIFLO
Sequence: MTENNEHLALWGGRFTSGPSPELARLSKSTQFDWRLADDDIAGSRAHARALGRAGLLTADELQRMEDALDTLQRHVDDGSFAPIEDDEDEATALERGLIDIAGDELGGKLRAGRSRNDQIACLIRMWLRRHSRVIAGLLLDLVNALIEQSEKAGRTVMPGRTHMQHAQPVLLAHQLMAHAWPLIRDVQRLIDWDKRINASPYGSGALAGNTLGLDPEAVARELGFSRVTDNSIDGTAARDLVAEFAFVAAMTGVDISRLSEEIIIWNTQEFAFVKLDDGYSTGSSIMPQKKNPDIAELARGKSGRLIGDLTGLLATLKGLPTAYARDLQEDKEAVFDQVDTLEVLLPAFTGMVRTMHFDGDRLEEEAPTGFALATDIAEWLVKNGVPFRHAHELSGACVKLAEGRGQELWDLTDNDFIETFAAFLPADKAPGVREVLSSHGSVDSRNGKGGTAYGRVREQIADAKAEVEELKLFPASTSDGSAYKAPGTF
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RN_DROME
Sequence: MIMHGTWYKGPQLAHHPHSNPHNSSHGHSDYHQFRSYPSFVVTPYHDGHVQGPATPTPCTAPPTPCNGPVPVSVPVSIPVCHTGGQGSPVIVESSFAIAAAAAAAAAAVAVGGSSATPLLPSPPIKIEQVFGEPSSLGAVVEDYALGLDCPVEHTFRKPHNNNGYSWSTGNNNEVVSHSSNGHTNNHPTTPPTPPNEASATQATSVSAINLNQAQPASQTRSNFGSSIKSPPSEPDAVTAATCKSQENNSGQNPTPNSLSDHNPAHNLNSNSTAAAVAAAAAAAAAANMPIGGVQGQNPTQGLVHWMSAVMAEHMTGQTHHDPGAVGMHYMWNGNVDHAKDISDYNLWPPTPRSHQHASEHHPMSLKQEYEAKMNDHHHNNLQKGHFLDDNRLEHHAVTGQGGLGLGASNGVGGGGGGASVVGNSSLGASSHHAVAAAHHHNQAVAAASAAALLVVPQPINASKMGGPGGVSSVAGGHATGGGSGRKYQCKMCPQIFSSKADLQLHTQIHMREAKPYKCTQCSKAFANSSYLSQHTRIHLGIKPYRCEICQRKFTQLSHLQQHIRTHTGDKPYKCRHPGCQKAFSQLSNLQSHSRCHQTDKPFKCNSCYKCFSDEPSLLEHIPKHKESKHLKTHICQYCGKSYTQETYLTKHMQKHAERTDKRPPIVPGSAAAIAAAAAAAAGGSANPANGPPPPPNPAQHQRNNLGLPPVSIAPSDNGYWPKVSPDSAAAANAMEVMHQQQQQQQQQQQQQQQQQQQQQQQAHHHHPQHGVPPQQHVPPQQQQQQQQQQQHHHPQQQPPPQHSMEAHYAQPTAPNGSQSNGHGAELQPHHRMPDPVREDIASTPSAVGPYDAASITKTTSNSAFTPINSMPPHLNSLSHHPMAQRPYLYDAISFPNKNVNQNNANAFPNQLISLHQIRNYAHQPAGLMAGEHLLGVSVGPGKDKG
What is the function of this protein?
Transcription factor involved in imaginal disks development.  Isoform rn is required in the wings, antenna, haltere, proboscis and legs disks, while isoform roe is required in the eye disk.  Together with nab corepressor, it is involved in the initiation and maintenance of wingless (wg) expression in the wing hinge, by limiting the expression of wg to this compartment.  Also required for the epithelial-mesenchymal transition branch of basolateral junctions signaling.
What are the official names of this protein?
Zinc finger protein rotund, Zinc finger protein roughened eye.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DAPB_BORPE
Sequence: MTQATPQRIAIAGASGRMGQMLIEAVLDTEGVELAVALDRAGSPSIGQDAGAALGRPCGVTITDQLDALAQADCLIDFTRPEGTLQHLQACLRHDVKMVIGTTGFDSSGRAEIKVAAQKIAIVFAPNMSVGVNATLKLLDMAARILNSGYDVEIFEAHHRNKVDAPSGTALIMGETVASAWDVALPDVATWTRHGDTGVRKPGTIGFSVVRGGDIVGDHTVFFCGTGERIEISHRSSSRATYAQGAVRAARFLARQDNGLYDMQAVLGL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_PROM2
Sequence: MSLEEKKTTESKEKDKALSLVLGQIERNFGRGSIMRLGDASRMKVETISTGALTLDLALGGGYPKGRVVEVYGPESSGKTTLTLHAIAEVQKNGGVAAFVDAEHALDPVYAASLGVDVENLLVSQPDTGEMALEIVDQLIRSSAVDLVVVDSVAALTPRAEIEGEMGDHVIGSQARLMSQAMRKITGNIGKSGCTVIFLNQLRLKIGITYGNPETTTGGNALKFYASVRLDIRRIQTLKRGTEEYGIRAKVKVAKNKVAPPFRIAEFDILFGKGISTTGCLLDLAEETNIIIRRGAWYSYEGENIGQGRDNTIIWLDQNLEIKNKVESMIKEKLTEGTEVSSNSMKALNSNPTSTIAVNDIKTVA
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_NOCSJ
Sequence: MHCPYCRNTDTRVLDSRVADDGGSIRRRRTCSACAKRFTTVELMQLTVLKRSGASEPFTREKAVAGVRKACKGRPVTEDQLACLGQAVEDALRLDGAAEVPAHEVGLAILGPLRELDEVAYLRFASVYRAFESADDFEDEIAMLRAERPAVAIEPVTVPATEPAPPQPVATG
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: GTHB2_CLUPA
Sequence: MARIPECTILLLLCMCVLAVPAQCFNLQPCVLVNETVSVEKEGCPRCLVFRTTICSGHCPTKEPVYKSPFSVVNQHVCTYGNFRYETIRLPDCADGVDPLVTYPVALSCECSLCSMDTSDCTIESVEPDFCMSQRLPVYESQKPSLYDY
What is the function of this protein?
Involved in gametogenesis and steroidogenesis.
What are the official names of this protein?
Gonadotropin subunit beta-2, GTH-II-beta, Gonadotropin beta-II chain.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL3_RHILW
Sequence: MRSGVIAQKVGMTRVYNDAGEHVPVTVLRMDGCQVVATRTVEKNGYTAVQLGAGQAKVKNTSKAMRGNFAVANVEPKAKVAEFRVSEDQLLEIGTEIKAGHFAAGQLVDVTGTTIGKGFAGAMKRHGFGGLRATHGVSVSHRSHGSTGSRQDPGKVFKNKKMAGHMGQTRVTTQNLEVVSTDEDRGLILIKGAVPGSKGAWIIVRDAVKSAAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: AP2B_HUMAN
Sequence: MHSPPRDQAAIMLWKLVENVKYEDIYEDRHDGVPSHSSRLSQLGSVSQGPYSSAPPLSHTPSSDFQPPYFPPPYQPLPYHQSQDPYSHVNDPYSLNPLHQPQQHPWGQRQRQEVGSEAGSLLPQPRAALPQLSGLDPRRDYHSVRRPDVLLHSAHHGLDAGMGDSLSLHGLGHPGMEDVQSVEDANNSGMNLLDQSVIKKVPVPPKSVTSLMMNKDGFLGGMSVNTGEVFCSVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGGVLRRAKSKNGGRSLRERLEKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYICETEFPAKAVSEYLNRQHTDPSDLHSRKNMLLATKQLCKEFTDLLAQDRTPIGNSRPSPILEPGIQSCLTHFSLITHGFGAPAICAALTALQNYLTEALKGMDKMFLNNTTTNRHTSGEGPGSKTGDKEEKHRK
What is the function of this protein?
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes.  AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development.  They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.  AP-2-beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia.
What are the official names of this protein?
Transcription factor AP-2-beta, AP2-beta, Activating enhancer-binding protein 2-beta.
What is the protein family that this protein belongs to?
Belongs to the AP-2 family.
What are the subcellular locations of this protein?
Nucleus. Note=In the brain, localizes to the arcuate hypothalamic nucleus, the ventromedial hypothalamic nucleus and the accumbens nucleus of the ventral striatum.
Protein: PYRR_STRS2
Sequence: MKTKEIVDDMTMKRAITRITYEIIERNKNLDNIVLAGIKTRGVFIAKRIQERLKQLEGIDVPLGELDTKPFRDDMKVEDDTTNMTANVNDRDVILVDDVLYTGRTIRAAIDNIVSLGRPARVSLAVLVDRGHRELPIRADYVGKNIPTSRSEEIIVHMAEIDGQDAVLLVEGA
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: HOXQ_AZOVI
Sequence: MNDDLPILPPGFGPGSHGEEERPDCPSMPRAMRRFERPALPEPGQLSGHPIALALLERLQEALGAYRIGEQSRVIGLDRQPKADLKLLQQILGEGEVAIQVGGQRPARIQETVLAGVWWVQLQIGRGEVVGQWLEVADVPALVRRRAFAETRWPQLGELPDGLLNAGPVLVELLDAAKRHAERALATPHAVNLSLLPFSPEDRRFLAERLGEGSVTLLSRGYGNCRIASTATPGIWCVQYFNSSDRLILDTLEVTGIPQVACAAQEDIDDSAERLREIREALE
What are the official names of this protein?
Hydrogenase expression/formation protein HoxQ.
What is the protein family that this protein belongs to?
Belongs to the HupH/HyaF family.
Protein: RL8_PONAB
Sequence: MGRVIRGQRKGAGSVFRAHVKHRKGAARLRAVDFAERHGYIKGIVKDIIHDPGRGAPLAKVVFRDPYRFKKRTELFIAAEGIHTGQFVYCGKKAQLNIGNVLPVGTMPEGTIVCCLEEKPGDRGKLARASGNYATVISHNPETKKTRVKLPSGSKKVISSANRAVVGVVAGGGRIDKPILKAGRAYHKYKAKRNCWPRVRGVAMNPVEHPFGGGNHQHIGKPSTIRRDAPAGRKVGLIAVRRTGRLRGTKTVQEKEN
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL37A_THESM
Sequence: MPRTKKVGSAGRFGPRYGLKIRRRVAAVEEKMRQKHTCPVCGRKAVRRISTGIWQCQKCGATFAGGAYLPATPAGRIAKRGISSP
What are the official names of this protein?
50S ribosomal protein L37Ae, Ribosomal protein L43e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL43 family.
Protein: F16PA_XANFL
Sequence: MLEPNADHRAAVAQAAGVAASRITLTVMLDEWAGADARRRAVADTVCALATGCASLAAAIAEGPLAGDLARTLSSGEAGEGQKALDVISNDIVIGALKAAPVAAVASEENDAPVLLDPTAPLLVAIDPLDGSSNIDTDISVGTIFAVFPRPEGADASEPSAFLQNGRDMLAAGYVIYGPHTAMMLTLGAGTWHFALDRAGLFRLVDAEVKVKEGAAEFAINMSNYHHWDVPVRDYVDDCLAGKKGPRERDFNMRWVASMVADAHRIFQRGGIYLYPGDGRKGYTHGRLRLLYEAFPVAFLMEQASGSATDGRGAILDLSATGLHQRVPFIFGSRDEVARVSRYHLEPNGHGERSPLFARRGLFI
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPS_SHEWM
Sequence: MGKAGNIEHVEERVESEVMPPSMYKVILNNDDYTPMDFVIEVLQLFFKKTEEQATDIMLAIHHQGKGICGIFPFGIAETKVAQVNQFARQNQHPLLCSLEKA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: COX3_DROYA
Sequence: MSTHSNHPFHLVDYSPWPLTGAIGAMTTVSGMVKWFHQYDISLFLLGNIITILTVYQWWRDVSREGTYQGLHTYAVTIGLRWGMILFILSEVLFFVSFFWAFFHSSLSPAIELGASWPPMGIISFNPFQIPLLNTAILLASGVTVTWAHHSLMESNHSQTTQGLFFTVLLGIYFTILQAYEYIEAPFTIADSVYGSTFYMATGFHGVHVLIGTTFLLVCLLRHLNNHFSKNHHFGFEAAAWYWHFVDVVWLFLYITIYWWGG
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DEOB_ALKCK
Sequence: MKKRFERIFLIVMDSVGIGEAPDAKEFGDEGANTLGSIAEAFNGLHVPELEKLGLGKIAPLKGVKNVPTPLASYGIMQEASLGKDTMTGHWEIMGLHITKPFQVFPDGFPTELLEQLKSETGRGIIGNKVASGTEILDELGEEHVKTGDLIVYTSADSVLQIAAHEEVVPLEELYDICEKARKLTLAPEYMVGRVIARPFVGEPGKWKRTANRHDYALKPFGRTVMNTLEDAGLASIALGKISDIYDGEGVTKAVRTTSNEDGMDKLAEQINTSFEGLCFLNLVDFDALYGHRRDVIGYGEAIMAFDQRLGEILPQLGDEDLLIVTADHGNDPTHTGTDHTREYVPLLVYNKGIKPVNLGKRRTFADIGATVADNFQVERPSNGTSFLTELKPE
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSK3_CAEBR
Sequence: MNKQLLSCSLKSGKQVTMVVASVATDGVDQQVEISYYDQKVIGNGSFGVVFLAKLSTTNEMVAIKKVLQDKRFKNRELQIMRKLNHPNIVKLKYFFYSSGDKKDELYLNLILEYVPETVYRVARHYSKQRQSIPMIYVKLYMYQLLRSLAYIHSIGICHRDIKPQNLLIDPETGILKLCDFGSAKYLVRNEPNVSYICSRYYRAPELIFGATNYTNSIDVWSAGTVIAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIQSMNPNYKEFKFPQIKAHPWNKVFRVHTPAEAIDLISKIIEYTPTSRPTPQAACQHAFFDELRSPDARLPSGRALPQLEMDGPNEVSATGGDMAGPSA
What is the function of this protein?
Phosphorylates oma-1, a regulator of the oocyte-to-embryo transition, enabling its degradation.  Phosphorylates skn-1, preventing it from accumulating in nuclei and thus inhibiting phase II gene expression in the oxidative stress defense.  Involved in mesendoderm specification and mitotic spindle orientation in EMS blastomeres.  Thought to be a branch point in these processes as proteins downstream are not required.  Negatively regulates Wnt signaling in vulval precursor cells and acts as a Wnt-independent repressor of med-1 and med-2 in the C lineage inhibiting mesoderm development.  Required for normal lifespan and LiCl-induced lifespan extension (By similarity).
What are the official names of this protein?
Glycogen synthase kinase-3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.