PharMolix/UniProtQA huggingface dataset:
Protein: THIM_ROSCS
Sequence: MDTINQRIGEMLARVRATRPLIHHITNLVVMNDTANVTLHVGGLPVMAHDVEEVAEMVTHAGALVLNVGTLSPDWVESMLVAGRQANELDIPIVLDPVGAGATQLRTMTNLKLLRSLHIGVVRGNGGEIGALSGAGGEMRGVESIAAPENPLTAARTLAQTYRTVVALTGARDIITDGERGFIVSNGHIWLTTLTGTGCMATTMVAAFAAVERDYLLAAAGGLAMFGLAAELAAEKAHGPASFKTALFDQIYNLTPEQVAAGARIAELEW
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: YR634_MIMIV
Sequence: MTNTFYLLPVEIWVKIVNFSNETSLLLTNKEFFELSSLINVEQNIFEYVIRNDYWHILDYVSNLEKNKSEKYPIVCKFKEYTNDLFKYVIEFCISGKLDSIKRLVSMGANVREHNDVALNRAVENGHMDIFEYLISKGADLYANKNTLVRCASYGGNLDMVKYLISIGANFRENCDTPLIWACHNGHLEIVKYLVDQGADVNSQSHKSIITASKMGHLGIVKYLVSKTTNIDWRHNYAAAFAAQNNHLEIVKYLVNEGANLEIEDGCIIRVAAKNGHLDIVKYLVSLGMEIGFKKILIGTSNFGVVNKITPVIGSAVEGGHLSMVKYFVSIGATIKEKNYAFVKAAEYGHLEIIKYLVSQGISLEKKINKALIVACSKGHLEIVKYLVENGANVKTNEGLPLRQACWGNYLDIAKYLVSNGADVTSYDNYALKTALEKGDLETVKYFIYVGANVNDISSWDLKFISVLGRSEVLEYLKSTFNIKLS
What are the official names of this protein?
Putative ankyrin repeat protein R634.
Protein: CC181_PONAB
Sequence: MNEDKDTDSKKSEEYEDDFEKDLEWLINENEKSDASIIEMACEKEENINQDLKENETVIEHTKQHSDPDKSLQDEVSPRKNDIISVPGIQPLDPISDSDSENSFQESRLESQKDLEEEEDEEVRRYIMEKIVQANKLLQNQEPVNDKRERKLKFEDKLVDLEVPPLEDTTTSKNYFENERNMFGKLSQLCISNDFGQENVLLSLTNVSCEENKDRTILVERDGKFELLNLQDIASQGFLPPINNANTTENDPQQLLPRSSNSSVSGTKKEDSAAKIHAVTHSSTGKPLAYIPQPPLNRKTCPSSAVISDQSKGNGNSNHRAQSAHISPVTSTCCLSPRQKELQKQLEQKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAKEIEDMNSRQENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERAFKQWLRRKRIEKMAEQQAVRERTRQLRLEAKRSKQLQHHLYMSEAKPFRFTDHYN
What is the function of this protein?
Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids.
What are the official names of this protein?
Coiled-coil domain-containing protein 181.
What is the protein family that this protein belongs to?
Belongs to the CCDC181 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, cilium, flagellum. Note=Localizes to the microtubular manchette of elongating spermatids. Localizes to the sperm flagella and to the basal half of motile cilia.
Protein: STYA_STYCL
Sequence: GXFGKAFXSVSNFAKKHKTA
What is the function of this protein?
Bactericidal against several Gram-positive and Gram-negative bacteria.
What are the official names of this protein?
Styelin-A.
What are the subcellular locations of this protein?
Secreted.
Protein: DEF_UREP2
Sequence: MYNIKFLDLLNSNLKPNPQWIFKDPHPILREVTQDIEGNELSKDDIYYLKKMVRYIDVCYHNQAKKYKIRSGIAIAANQVGWNKRATYIHFNDEAKEHHYLLINPHIIKRSSEIAYLNPGEGCLSVDDDRSGYVIRNKKVHVKAYDLISEQFIDQEFSGIIAICIQHEIGHLDAGLYYDNINQQQPFYADPSWTKIGR
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: RL9_STRMK
Sequence: MQLILLQKVTNLGNLGDLVDVKPGYGRNFLVPQGKAVPATESNKAEFEAKRAEYEAKAQAIHADAEGRKAKLEGASVTIAANASTEGKLYGSVGPRDIAEAFTAAGLPLEKSEVILGEGAFRNIGEYDVLVHLHADVETTVKVVVVAEA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: RS19_ASTYP
Sequence: MPRSVKKGPIVASHLLAKIEKQKNLKNKKVIQTWSRSSTITPIFVGHKIAVYNGREHIPVYITENMVGHKLGEFSPTRTYRGHNKKDKKIQKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: RUBR_AZOCH
Sequence: MSTRFEGSYLGNAARLADDAVLECKICWHRYDPAVGDEVWQILAGTPFAALPAHWRCPQCDGDREQFMVVDD
What is the function of this protein?
Could be an electron transport intermediate in hydrogen oxidation.
What are the official names of this protein?
Rubredoxin in uptake hydrogenase operon.
What is the protein family that this protein belongs to?
Belongs to the rubredoxin family.
Protein: KTIL_BOTSC
Sequence: MKVNCKGYPTKFCFGKPLPHCASDGKTYPNRCRFCNAFVKSHGLITLRYYGKCK
What is the function of this protein?
Partially inhibits trypsin in vitro at slightly acidic pH and concentrations in excess of 0. 3 mM.  Has no protease inhibitory activity at neutral or basic pH.  Has no antibacterial activity.  Shows no toxicity in vertebrates apart from transient paw edema in mouse.
What are the official names of this protein?
Kazal-type inhibitor-like protein, KTIL.
What are the subcellular locations of this protein?
Secreted.
Protein: ZN318_HUMAN
Sequence: MYRSSARSSVSSHRPKDDGGGGPRSGRSSGSSSGPARRSSPPPPPSGSSSRTPARRPRSPSGHRGRRASPSPPRGRRVSPSPPRARRGSPSPPRGRRLFPPGPAGFRGSSRGESRADYARDGRGDHPGDSGSRRRSPGLCSDSLEKSLRITVGNDHFCVSTPERRRLSDRLGSPVDNLEDMDRDDLTDDSVFTRSSQCSRGLERYISQEEGPLSPFLGQLDEDYRTKETFLHRSDYSPHISCHDELLRGTERNREKLKGYSIRSEERSREAKRPRYDDTVKINSMGGDHPSFTSGTRNYRQRRRSPSPRFLDPEFRELDLARRKREEEEERSRSLSQELVGVDGGGTGCSIPGLSGVLTASEPGYSLHRPEEVSVMPKKSILKKRIEVDIMEPSMQLESFSSSTSSSQDHPLYSGHPSLPLSGAIAAFASEIENKGTMVETALKEPQGNLYQWGPLPGIPKDNSPLREKFGSFLCHKDNLDLKAEGPERHTDFLLPHERASQDGSGFSRILSMLADSTSTQEKRRRSFPDIEDEEKFLYGDEEEDLKAESVPKPLGSSESEVMRQKASSLPSSAPAVKLESLEETNPEYAKIHDLLKTIGLDIGVAEISQLAARTQERLHGKKPSLRSSADRRSSVDRYFSADHCSSVDHRFSADRCSSVDHCFSADRRSSDPHRLESREAHHSNTHSPEVSHPHPPSPVDPYLLTKNSPPFLKSDHPVGHISGPEVVGSGFQSSVAVRCMLPSAPSAPIRLPHTAALSQFHMPRASQFAAARIPPNYQGPAIPPASFDAYRHYMAYAASRWPMYPTSQPSNHPVPEPHRIMPITKQATRSRPNLRVIPTVTPDKPKQKESLRGSIPAAQVPVQVSIPSLIRYNPEKISDEKNRASQKQKVIEEREKLKNDREARQKKMYYLRTELERLHKQQGEMLRKKRREKDGHKDPLLVEVSRLQDNIMKDIAELRQEAEEAEKKQSELDKVAQILGINIFDKSQKSLSDSREPTEKPGKAEKSKSPEKVSSFSNSSSNKESKVNNEKFRTKSPKPAESPQSATKQLDQPTAAYEYYDAGNHWCKDCNTICGTMFDFFTHMHNKKHTQTLDPYNRPWASKTQSEAKQDAIKRTDKITVPAKGSEFLVPISGFYCQLCEEFLGDPISGEQHVKGHQHNEKYKKYVDENPLYEERRNLDRQAGLAVVLETERRRQSELKRKLSEKPKEEKKEKKAKAVKEVKEDDKVSEKLEDQLSEGRNSPEKAENKRNTGIKLQLKEEVKKESPTSSSFGKFSWKKPEKEEEKSSLVTPSISKEEILESSKDKEDGKTEAGKAKPIKIKLSGKTVVAHTSPWMPVVTTSTQTKIRPNLPIPSTVLRKSCSATMSKPAPLNTFLSIKSSGTTAKPLPVVKESSADLLLPPDIISKAFGGEEVILKGSPEEKVVLAEKSEPSHLPEQILPPPPPPPPPPPPPPPVIPHPAAPSAAQANAILAPVKSNPVVSQTLSPGFVGPNILNPVLPVAIMASAQPAAIPSDETAPGVSESDRDQTLFSVLVRPPPPLSSVFSEQAKKLEKRNSCLATANAKDLYDIFYSSGGKGAPETKGAPETKLSGGPLANGENSNLSRTKSSDTSSTSPLNSSASQEELHQDEGLVAAPIVSNSEKPIAKTLVALGKWSVVEHVGPKSTGSTYGFLQPLTRLCQSRPYETITPKTDTLAIWTSSSFQSDTSRDISPEKSELDLGEPGPPGVEPPPQLLDIQCKESQKLVEIHLRESVNQDKESQELRKSEDCRESEIETNTELKERVKELSEGIVDEGVSTSIGPHSIDDSNLNHGNRYMWEGEVKQPNLLMIDKEAEQSNKLMTGSETPSKVVIKLSPQACSFTKAKLDSFLSEARSLLNPQDTPVKISAPELLLHSPARSAMCLTGSPQEQGVSVVSEEGLENSAPESASRTSRYRSLKLKRERSKDFQVKKIYELAVWDENKKRPETWESPEKPKTEALELQDVHPELTVTIESKALEDFEATDLKVEELTALGNLGDMPVDFCTTRVSPAHRSPTVLCQKVCEENSVSPIGCNSSDPADFEPIPSFSGFPLDSPKTLVLDFETEGERNSPNPRSVRIPSPNILKTGLTENVDRGLGGLEGTHQALDLLAGGMMPEEVKESSQLDKQESLGLELKTINSAGLGPSPCLPDLVDFVTRTSGVQKDKLCSPLSEPGDPSKCSSLELGPLQLEISNASTTEVAILQVDDDSGDPLNLVKAPVSRSPPREQVIEDNMVPQGMPEQETTVGAIQDHTESSVHN
What is the function of this protein?
Acts as a transcriptional coactivator for AR-mediated transactivation function.  May act as a transcriptional regulator during spermatogenesis and, in particular, during meiotic division.
What are the official names of this protein?
Zinc finger protein 318, Endocrine regulatory protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: DB115_HUMAN
Sequence: MLPDHFSPLSGDIKLSVLALVVLVVLAQTAPDGWIRRCYYGTGRCRKSCKEIERKKEKCGEKHICCVPKEKDKLSHIHDQKETSELYI
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Beta-defensin 115, Beta-defensin 15, DEFB-15, Defensin, beta 115.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GLYA_CLOBK
Sequence: MDFTNLKNTDPELLDMIKKEEERQEYNIELIASENFTSLSVMEAMGSLLTNKYAEGYPHKRYYGGCEFVDEVEDLARERLKKLFVAEHANVQPHSGSQANMAVYMSVLQTGDTILGMDLSHGGHLTHGSPVNFSGKLYNFISYGVDKETETIDYDQLKKIALENRPKMIVSGASAYPRIIDFEKIREICDEIDAYMMVDMAHIAGLVATGIHPSPVPYADFVTTTTHKTLRGPRGGAILCKEKYAKAVDKAIFPGIQGGPLMHTIAAKAVCFGEALREDYKEYMQQVVKNTKVLGEELKNYGFRLISGGTDNHLLLIDLTNKNITGKDAEKLLDSVGITVNKNTIPFETLSPFITSGIRIGTPAVTTRGFKEEEMKKIAYFMNYSIEHREENLSQIKEQIKEICKKYPLHQNA
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DF244_ARATH
Sequence: MKGIAMLLVSCLLFSFLSTNLAKELKWCPSKDVFNGSCTDTGSPSYTCFLDLLGSKSASAMPKNCKCTPLPHNRRQCDCFVVCDSN
What are the official names of this protein?
Putative defensin-like protein 244, Putative S locus cysteine-rich-like protein 11, Protein SCRL11, SCR-like protein 11.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: GLMM_STRZP
Sequence: MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKVFVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASHNPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKYEGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGSTHPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLAQNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMDYNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAIKAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: CLPX3_ARATH
Sequence: MSGLWRLRNLKSLALHARSISPVSNLYSLELGSCPRRRIQERFKSEQGGGGGGGDDFPVPVTRRKLRAEPNCPRCSKQMDLLFSNRQFPSSNLLQRPDDSDSSGAGDKTNFQSVNFCPTCKTAYGFNPRGVSPLQGTFIEIGRVQSPTTTTTNATTSKSTRKQQQHSKDPNQGFNYRNKLRSSFWDTLRSYGAEPPEDWSPPPPHSPLNSSPPNTIPVNASPSAVDTSPLPDAVNDVSRWGGAGLGRDFPTPKEICKWLDKFVIGQSRAKKVLSVAVYNHYKRIYHTSMKKGSAAQPIDDDDNVELDKSNVLLMGPTGSGKTLLAKTLARLVNVPFVIADATTLTQAGYVGDDVESILHKLLTVAEFNVQAAQQGIVYIDEVDKITKKAESLNISRDVSGEGVQQALLKLLEGTIVNVPGKGARKHPRGDHIQIDTKDILFICGGAFVDLEKTIVDRRQDSSIGFGAPVRANMATSGVTSGAITSSLLESVESADLTAYGLIPEFVGRFPILVSLSALTEDQLIRVLVEPKNALGKQYKKLFSMNNVKLHFTEKALEIISKQAMVKNTGARGLRALLESILTEAMFEIPDDKKGDERIDAVIVDEESTSSEASRGCTAKILRGDGAFERYLSENKSKDATEPMVDERVGSAKAMRL
What is the function of this protein?
ATP-dependent specificity component of the mitochondrial Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
CLP protease regulatory subunit CLPX3, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: LEUC_HERAR
Sequence: MAQTLYDKLWQSHVVDTGDDGTTVLYIDRHLLHEVTSPQAFEGLKLAGRRPWRVSANLMVADHNVPTTDRSEGIADPTSRLQVETLDHNAHEYGLTYFSMRDKRQGIVHVIGPEQGATLPGMTVVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQTLLAQKSKAMLVQVDGALPVGVTAKDIVLAIIGKIGTAGGTGYAIEFAGSTIRSLSMEGRMTICNMAIEAGARAGMVAVDETTINYVKGRPLSPVGPHWDRAVEYWRTLHSDVGAKFDLVVTLNAAEVKPQVSWGTSPEMVVSVDGRVPDPDKEKDATKRDGMEKALVYMGLKPNTPITDIRIDKVFIGSCTNSRIQDLRAAAAVVRGKHRASNVKLAMVVPGSGLVKEQAEREGLDKIFKDAGFEWREPGCSMCLAMNADRLEPGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAGIEGHFVDVRAL
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: MPRF_STAA8
Sequence: MNQEVKNKIFSILKITFATALFIFVAITLYRELSGINFKDTLVEFSKINRMSLVLLFIGGGASLVILSMYDVILSRALKMDISLGKVLRVSYIINALNAIVGFGGFIGAGVRAMVYKNYTHDKKKLVHFISLILISMLTGLSLLSLLIVFHVFDASLILDKITWVRWVLYVVSFFLPLFIIYSMVRPPDKNNRFVGLYCTLVSCVEWLAAAVVLYFCGVIVDAHVSFMSFIAIFIIAALSGLVSFIPGGFGAFDLVVLLGFKTLGVPEEKVLLMLLLYRFAYYFVPVIIALILSSFEFGTSAKKYIEGSKYFIPAKDVTSFLMSYQKDIIAKIPSLSLAILVFFTSMIFFVNNLTIVYDALYDGNHLTYYILLAIHTSACLLLLLNVVGIYKQSRRAIIFAMISILLITVATFFTYASYILITWLAIIFVLLIVAFRRARRLKRPVRMRNIVAMLLFSLFILYVNHIFIAGTLYALDIYTIEMHTSVLRYYFWLTILIIAIIIGMIAWLFDYQFSKVRISSKIEDCEEIINQYGGNYLSHLIYSGDKQFFTNENKTAFLMYRYKASSLVVLGDPLGDENAFDELLEAFYNYAEYLGYDVIFYQVTDQHMPLYHNFGNQFFKLGEEAIIDLTQFSTSGKKRRGFRATLNKFDELNISFEIIEPPFSTEFINELQHVSDLWLDNRQEMHFSVGEFNEEYLSKAPIGVMRNEENEVIAFCSLMPTYFNDAISVDLIRWLPELDLPLMDGLYLHMLLWSKEQGYTKFNMGMATLSNVGQLHYSYLRERLAGRVFEHFNGLYRFQGLRRYKSKYNPNWEPRFLVYRKDNSLWESLSKVMRVIRHK
What is the function of this protein?
Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge.  LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms (bacteriocins).  In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides.  Consequently, MprF is shown to affect resistance and susceptibility to moenomycin and vancomycin, resistance to human defensins (HNP1-3) and evasion of oxygen-independent neutrophil killing and susceptibility to methicillin, oxacillin, bacitracin, gentamicin, beta-lactams and synthetic peptides (hBD3, CAP18) and other cationic antimicrobial peptides.
What are the official names of this protein?
Phosphatidylglycerol lysyltransferase, Lysylphosphatidylglycerol synthase, LPG synthase, Multiple peptide resistance factor.
What is the protein family that this protein belongs to?
Belongs to the LPG synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ACSF_PROM0
Sequence: MSQSTIESTNKKEINKGKAPAKETILSPRFYTTDFEAMENMDLSINEEELEAICEEFRKDYNRHHFVRNSEFEGAAEKLDPETRELFVDFLEGSCTSEFSGFLLYKELSKRIKDKNPLLAECFAHMARDEARHAGFLNKSMSDFGLQLDLGFLTANKDYTYFPPRSIFYATYLSEKIGYWRYIAIYRHLEKNPNSKIFPLFNYFENWCQDENRHGDFFDALMKAQPRTVKSLSQKITIGGSTFTHPLFDYFHRFRYFLNNLPLTSKLWSRFFLLAVFATMYARDLGIKKDFYSSLGLDARDYDQFVINKTNETAARVFPVVMDVNNKSFYGRLDKIVENNKILSDIASGTGNKVSKTFRKVPKYLSNGYQLLRLYLLKPLDSKDYQPSIR
What is the function of this protein?
Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis.  Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME).
What are the official names of this protein?
Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase, Mg-protoporphyrin IX monomethyl ester oxidative cyclase.
What is the protein family that this protein belongs to?
Belongs to the AcsF family.
Protein: FMRA_CALPA
Sequence: MLVAMTTASYVTILVTLLFHILTINAKTVTKRAKETNLEDDEPQYWRGRFAKDVVPQFWKGRFSDPQFWKGRFSDPQFWKGRFSSHGNKRRYVPGRYGREFQGRFGREFQGRFGREQGRFGREEDQGRFGREEDQGRFGREEQGRFGREEDQGRFGREEDQGRFGREEDQGRFGREEEQGRFGREEDQGRFGREEEQGRFGREEDQGRFGREEDQGRFGREEEQGRFGKRDEDQGRFGKREDQGRFGKRDEDQGRFGKRDEDQGRFGKREDQGRFGKREDQGRFGRELLAKLNKRTTSIQEDPQTRFRDVQMTRRNVAKKDKIEESNDEEANKS
What is the function of this protein?
Not known but it could act as a transmitter at neuromuscular synapses.
What are the official names of this protein?
Antho-RFamide neuropeptides.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL30_ACTP2
Sequence: MAKTIKVTQTRSSIARLPKHKATLKGLGLRHIRHTVELIDTPAVRGMINQVSYMVKVEE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: HYAL5_MOUSE
Sequence: MRVLYFKHSFFRSLLKSNGLPQTLLVFLLIPCYLTVDFRAPPLIPDVPFLWAWNAPTESCFTRFNQPLDLGLFSLVGSPRKSATGQPVTIFYSDRLGLYPYIDDSQLIFNGGLPQLVSLKSHLEVAKTDILHYMPIDNVGLAVIDWEEWRPTWARNWKPKDIYRNKSIELVQQQNILLNFTEAVKWAKEEFEEAARHFMEETLRLGKSLRPNHLWGFYLFPDCYNNKFQVADYKGECPDIEKHRNDALFWIWEESTALYPSIYLKSSLKSSPQAALYVRNRVQEAIRVSKVKDPRNPLPIFVYFRIVFTDLTYQYLYEDDLVNTIGETIALGTSGMVMWGTLSLSQTMKSCLDLHDYLKTILNPYIINVTLAAKMCSQTLCQNQGVCSRKDWNSNDYLHLNPQNFQIHFVKHGKYEIRGNPTLENLLYFSQKFRCSCFAHLNCQERADIESVSTVSVCTLEDICINSLVISDKSELPKDWNRPYFVNSNQSDITSSATVSPCVPRKDVSGYLVVLSLYSQHLKYSL
What is the function of this protein?
Catalyzes the hydrolysis of hyaluronan into smaller oligosaccharide fragments (PubMed:16330764, PubMed:16925524, PubMed:19605784).  Does not appear to be essential for fertilization (PubMed:19605784).
What are the official names of this protein?
Hyaluronidase-5, Hyal-5, Hyaluronoglucosaminidase-5.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 56 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Cytoplasmic vesicle, secretory vesicle, acrosome membrane. Secreted. Note=Located on the plasma and acrosomal membranes of acrosome-intact (AI) sperm and released during the acrosome reaction.
Protein: VRK2_HUMAN
Sequence: MPPKRNEKYKLPIPFPEGKVLDDMEGNQWVLGKKIGSGGFGLIYLAFPTNKPEKDARHVVKVEYQENGPLFSELKFYQRVAKKDCIKKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMVMERLGIDLQKISGQNGTFKKSTVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLGYKNPDQVYLADYGLSYRYCPNGNHKQYQENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCMLRWLCGKLPWEQNLKDPVAVQTAKTNLLDELPQSVLKWAPSGSSCCEIAQFLVCAHSLAYDEKPNYQALKKILNPHGIPLGPLDFSTKGQSINVHTPNSQKVDSQKAATKQVNKAHNRLIEKKVHSERSAESCATWKVQKEEKLIGLMNNEAAQESTRRRQKYQESQEPLNEVNSFPQKISYTQFPNSFYEPHQDFTSPDIFKKSRSPSWYKYTSTVSTGITDLESSTGLWPTISQFTLSEETNADVYYYRIIIPVLLMLVFLALFFL
What is the function of this protein?
Phosphorylates 'Thr-18' of p53/TP53, as well as histone H3.  Reduces p53/TP53 ubiquitination by MDM2, promotes p53/TP53 acetylation by EP300 and thereby increases p53/TP53 stability and activity.
What are the official names of this protein?
Serine/threonine-protein kinase VRK2, Vaccinia-related kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. VRK subfamily.
Protein: CHEB1_XANOR
Sequence: MVDDSAVVRQVLVNVLNDAADIEVIATAADPLLAIEKMRKQWPDVIVLDVEMPRMDGITFLRKIMSERPTPVVICSTLTEKGARVTMDALAAGAVAVVTKPRLGLKQFLTESADELVATVRSAARANVKRLAARVTAVPLEAEVKHTADVILPAQSGRALAQTTERIVAIGTSTGGTQALEEVLTALPRVCPGIVIVQHMPEKFTAAFAARLNGLCQIAVKEAANNDRVMPGRALIAPGGKHLLLRRSGAQYFVEVLEGPPVNRHRPSVDVLFRSAARAAGSNALGIIMTGMGDDGAAGLLEMRQAGARTVAQDEQTSIVFGMPKEAIKRGGADRILPLGAMAREIVTQLQ
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 1.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_CHLTB
Sequence: MFKKFKPVTPGTRQLILPSFDELTTQGELKGSSSRRSVRPNKKLSFFKKSSGGRDNLGHISCRHRGGGVRRHYRVIDFKRNKDGIEAKVASVEYDPNRSAYIALLNYVDGEKRYILAPKGIKRGDRVISGEGSPFKTGCCMTLKSIPLGLSVHNVEMRPGSGGKLVRSAGLSAQIIAKTAGYVTLKMPSGEFRMLNEMCRATVGEVSNADHNLCVDGKAGRRRWKGIRPTVRGTAMNPVDHPHGGGEGRHNGYISQTPWGKVTKGLKTRDKRKSNKWIVKDRRK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: HFQ_TERTT
Sequence: MSKGHSLQDPYLNVLRKERIPVSIYLVNGIKLQGQVESFDQFVVLLKNTVSQMVYKHAISTVVPSRPVRVPMLNPESTGNDDMESGA
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: Y1430_LACDB
Sequence: MVNIYDTANQLANDLRETQQFLALKEAMDAVKADEGSLALFKELDAAQMEIMEAQQTGKELTEEQQDHFKSLNERVSQNTTLQSMLLAEQAVYTLLNDVQKNIGQPLSEAYEDLRKA
What are the official names of this protein?
UPF0342 protein LBUL_1430.
What is the protein family that this protein belongs to?
Belongs to the UPF0342 family.
Protein: 2A5A_MOUSE
Sequence: MSSPSPPAPVACAAISASEKVDGFTRKSVRKAQRQKRSQGSSQFRSQGSQAELHPLPQLKDATSNEQQELFCQKLQQCCVLFDFMDSVSDLKSKEIKRATLNELVEYVSTNRGVIVESAYSDIVKMISANIFRTLPPSDNPDFDPEEDEPTLEASWPHIQLVYEFFLRFLESPDFQPSIAKRYIDQKFVQQLLELFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINNIFLRFIYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLMKVLIPMHTAKGLALFHAQLAYCVVQFLEKDTTLTEPVIRGLLKFWPKTCSQKEVMFLGEIEEILDVIEPTQFKKIEEPLFKQISKCVSSSHFQVAERALYFWNNEYILSLIEENIDKILPIMFASLYKISKEHWNQTIVALVYNVLKTLMEMNGKLFDDLTSSYKAERQREKKKELEREELWKKLEELQLKKALEKQNNAYNMHSIRSSTSAK
What is the function of this protein?
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform, PP2A B subunit isoform B'-alpha, PP2A B subunit isoform B56-alpha, PP2A B subunit isoform PR61-alpha, PR61alpha, PP2A B subunit isoform R5-alpha.
What is the protein family that this protein belongs to?
Belongs to the phosphatase 2A regulatory subunit B56 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Chromosome, centromere. Note=From mitotic prophase to metaphase, localizes at the inner centromere between a pair of sister kinetochores. Decreased expression at the onset of anaphase (By similarity).
Protein: Y2409_STAHJ
Sequence: MKLFIILGALCTMMSVGTGAFGAHGLEGKLSDKYMSVWEKAVNYQMYHGLGLIIIGVISGTTSINVNWAGWLLFLGVVFFSGSLYILALTQIRILGAITPIGGLLFIAGWLMLIISTFKFVG
What are the official names of this protein?
UPF0382 membrane protein SH2409.
What is the protein family that this protein belongs to?
Belongs to the UPF0382 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSBT_WELMI
Sequence: MEALVYTFLLISTLGIIFFAIFFREPPKVPTKGGK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.