PharMolix/UniProtQA huggingface dataset:
Protein: END8_SALSV
Sequence: MPEGPEIRRAADNLEAAIKGKPLTDVWFAFAQLKPYESQLTGQIVTRIETRGKALLTHFSNGLTLYSHNQLYGVWRVIDTGEIPQTTRILRVRLQTADKTILLYSASDIEMLTADQLTTHPFLQRVGPDVLDARLTPEEVKARLLSPRFRNRQFSGLLLDQAFLAGLGNYLRVEILWQVGLTGQHKAKDLNEAQLNALSHALLDIPRLSYTTRGQADENKHHGALFRFKVFHRDGEACERCGGIIEKTTLSSRPFYWCPHCQK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine.  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Endonuclease 8, DNA glycosylase/AP lyase Nei, DNA-(apurinic or apyrimidinic site) lyase Nei, Endonuclease VIII.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: DNLJ_SALG2
Sequence: MEPIEQQLTELRTTLRHHEYLYHVMDAPEIPDAEYDRLMRELRELEAQRPDLITPDSPTQRVGAAPLTAFNQIRHEVPMLSLDNVFDEESFLAFNKRVQDRLKSTENVIWCCELKLDGLAVSILYENGVLVSAATRGDGTTGEDITSNVRTIRAIPLKLHGDNIPARLEVRGEVFLPQAGFEKINEDARRTGGKVFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGILEGGELPDTHLGRLLQFKAWGLPVSDRVTLCDSPQAVLDFYRNVEKDRPTLGFDIDGVVIKVNSLALQEQLGFVARAPRWAVAFKFPAQEQMTFVRDVEFQVGRTGAITPVARLEPVQVAGVLVSNATLHNADEIEQLGLRIGDKVVIRRAGDVIPQVVNVVLSERPEETRPIVFPTHCPVCGSDVERVEGEAVTRCTGGLICGAQRKESLKHFVSRRAMDVDGMGDKIIDQLVEREYVHTPADLFRLTAGKLTGLDRMGPKSAQNVVNALEKAKATTFARFLYALGIREVGEATAAGLAAYFGTLEALQTATIDELQKVPDVGIVVATHVFNFFAEESNRDVIGQLLAEGVHWPAPVVINVQEIDSPFAGKTVVLTGSLSQMSRDDAKARLAALGAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGITVIDEAEMIRLLGA
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: RL24_BURM1
Sequence: MNKIRKGDEVIVIAGKDKGKRGVVLAVAADRVTVEGINLVKKHVKPNPMKGTTGGVEAKTMPLHISNVAVVDANGKASRVGIKVEEGKKVRFLKTTGAVLSA
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: NORR_ECO5E
Sequence: MSFSVDVLANIAIELQRGIGHQDRFQRLITTLRQVLECDASALLRYDSRQFIPLAIDGLAKDVLGRRFALEGHPRLEAIARAGDVVRFPADSELPDPYDGLIPGQESLKVHACVGLPLFAGQNLIGALTLDGMQPDQFDVFSDEELRLIAALAAGALSNALLIEQLESQNMLPGDAAPFEAVKQTQMIGLSPGMTQLKKEIEIVAASDLNVLISGETGTGKELVAKAIHEASPRAVNPLVYLNCAALPESVAESELFGHVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRSLRVDVRVLAATNRDLREEVLAGRFRADLFHRLSVFPLSVPPLRERGDDVILLAGYFCEQCRLRQGLSRVVLSAGARNLLQHYSFPGNVRELEHAIHRAVVLARATRSGDEVILEAQHFAFPEVTLPPPEVAAVPVVKQNLREATEAFQRETIRQALAQNHHNWAACARMLETDVANLHRLAKRLGLKD
What is the function of this protein?
Required for the expression of anaerobic nitric oxide (NO) reductase, acts as a transcriptional activator for at least the norVW operon.  Activation also requires sigma-54.
What are the official names of this protein?
Anaerobic nitric oxide reductase transcription regulator NorR.
Protein: RECR_CAMJD
Sequence: MAKGLEKFNELVESFANLPTIGKKTAIRLAYHLCINNQIDGMKLAHNIENAIRFIKPCEQCGALSENELCEICSDEERSKNILCIVESPKDILTLEESQSYNGLYFVLDELNEEKLEKLKQILLKLNISELIFALTHSINSDATIFFIEDKFKDLNLTFSKIAQGIPSGVNLENVDLISLNKAMNFRTKI
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: RL21_METCA
Sequence: MYAVIQTGGKQYRVQPGDKVKVESLDAEAGQEVAFEKVLLIQSDDGVKIGQPFVSGGKVTGTVVAHGRHPKIRIIKFRRRKHHMKQAGHRQNYTEVQINEISA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: EZRA_STRPB
Sequence: MSSGIILLIVAIVLLVIIAYLVGVIIRKRNDSLITSLEERKQALFALPVNDEIEEVKSLHLIGQSQTSFREWNQKWVDLTVNSFADIENHIFEAENLNDTFNFIRAKHEINSVESQLNLVEEDIASIREALNILKEQEEKNSARVTHALDLYEKLQASISENEDNFGSTMPEIDKQMKNIETEFSQFVALNSSGDPVEASEVLDRAEEHTIALGQITEQIPAIVAKLEDDFPDQLDDLETGYRRLLEENYHFPEKNIEARFQEIRESIRANSSELVTLDLDRAREENTHIQERIDSLYEVFEREIAAYKVAAKNSKMLPRYLAHVKRNNEQLKDEIARLSRKYILSETESLTVKAFEKDIKEIEDSTLAVAEQFGLQEKPFSELQVTFERSIKTLTNVESGQMDVFAAVKDIEKIESQARHNLDVYVTQLHMIKRYMEKRHLPGIPQDFLSAFFTTSSQLEALMDELSRGRINIEAVSRLSEVATVAIANLEDLTYQVVQNATLTEQLLQYSNRYRSFEAGVQSSFEHALRLFEVENDYQASFDEISYALETVEPGVTDRFVNSYEKTREHIRF
What is the function of this protein?
Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation.  Inhibits FtsZ ring formation at polar sites.  Interacts either with FtsZ or with one of its binding partners to promote depolymerization.
What are the official names of this protein?
Septation ring formation regulator EzrA.
What is the protein family that this protein belongs to?
Belongs to the EzrA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=Colocalized with FtsZ to the nascent septal site.
Protein: DNAK_CHLTA
Sequence: MSEKRKSNKIIGIDLGTTNSCVSVMEGGQPKVIASSEGTRTTPSIVAFKGGETLVGIPAKRQAVTNPEKTLASTKRFIGRKFSEVESEIKTVPYKVAPNSKGDAVFDVEQKLYTPEEIGAQILMKMKETAEAYLGETVTEAVITVPAYFNDSQRASTKDAGRIAGLDVKRIIPEPTAAALAYGIDKEGDKKIAVFDLGGGTFDISILEIGDGVFEVLSTNGDTHLGGDDFDGVIINWMLDEFKKQEGIDLSKDNMALQRLKDAAEKAKIELSGVSSTEINQPFITIDANGPKHLALTLTRAQFEHLASSLIERTKQPCAQALKDAKLSASDIDDVLLVGGMSRMPAVQAVVKEIFGKEPNKGVNPDEVVAIGAAIQGGVLGGEVKDVLLLDVIPLSLGIETLGGVMTPLVERNTTIPTQKKQIFSTAADNQPAVTIVVLQGERPMAKDNKEIGRFDLTDIPPAPRGHPQIEVTFDIDANGILHVSAKDAASGREQKIRIEASSGLKEDEIQQMIRDAELHKEEDKQRKEASDVKNEADGMIFRAEKAVKDYHDKIPAELVKEIEEHIEKVRQAIKEDASTTAIKAASDELSTRMQKIGEAMQAQSASAAASSAANAQGGPNINSEDLKKHSFSTRPPAGGSASSTDNIEDADVEIVDKPE
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: KAD_DEIRA
Sequence: MTQSKNKVVIFLGPPGAGKGTQAARLAQEHQLVQLSTGDILRDHVARGTALGQQAGPLMEAGQLVPDELLIALIRDRLADMEPVRVIFDGFPRTQAQAEALDLLLEELGAPVSAVPLLEVPDQVLIDRIVDRGRQAVAEGRAPRADDNEETARKRQQVYREQTQPLIDYYARRGHLYTVDGLGTPDEVYERILSGMH
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_PROMM
Sequence: MISSNDFRTGTSIELDGSVWRVVEFLHVKPGKGSAFVRTKLKAVQSGNVVEKTFRAGEMLPQALLEKSTLQHTYMESGDYVFMDMSSYEETRLTAQQIGDSRKYLKEGMEVNVVSWNGNPLEVELPNSVVLEITETDPGVKGDTATGGTKPAILETGAQVMVPLFLSVGEKIKVDTRNDSYLGREN
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31B_PECCP
Sequence: MKAGIHPDYRTVVFHDTSADVYYRTGSTIKTDRTIELEGTSYPYVTIDVSSASHPYYTGKQKEYSKEGSTARFQQRFGNFFK
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: SLX9_ASHGO
Sequence: MVAKKRTQLRAKAMRQRRNSSEAMETEELPPDPKAFLHQLRESKREKQLNRSQSFLNRLRDQAGNGGISKSALRRRKKRMKEELKPRMEDLLTSLKEEGVLEEDESGELAAVTGVTAITASNGYSGLHDTAEACGTVRIRKNEPSIRTQRGAKLLTTKEQERFTKVISNERFRSSPFETLREIIKSRK
What is the function of this protein?
Involved in ribosome biogenesis.  Required for normal pre-rRNA processing in internal transcribed spacer 1 (ITS1).  May be involved in the movements of the replication forks (By similarity).
What are the official names of this protein?
Ribosome biogenesis protein SLX9.
What is the protein family that this protein belongs to?
Belongs to the SLX9 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: GPR_ECO57
Sequence: MVWLANPERYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHFDLANNYGPPPGSAEENFGRLLREDFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASLDQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHAVQSGKALYVGISSYSPERTQKMVELLHEWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVGCIAFTPLAQGLLTGKYLNGIPEDSRMHREGNKVRGLTPKMLTEANLNSLRLLNEMAQQRGQSMAQMALSWLLKDERVTSVLVGASRAEQLEENVQALNNLTFSTEELAQIDQHIADGELNLWQASSDK
What is the function of this protein?
Catalyzes the stereospecific, NADPH-dependent reduction of L-glyceraldehyde 3-phosphate (L-GAP).  The physiological role of gpr is the detoxification of L-GAP, which may be formed by non-enzymatic racemization of GAP.  Also involved in the stress response as a methylglyoxal reductase which converts the toxic metabolite methylglyoxal to acetol in vitro and in vivo (By similarity).
What are the official names of this protein?
L-glyceraldehyde 3-phosphate reductase, GAP reductase.
What is the protein family that this protein belongs to?
Belongs to the shaker potassium channel beta subunit family.
Protein: SYY_LACLM
Sequence: MNIFDELKARGLVFQTTDEAALSKALTEDMVSYYVGYDPTADSLHLGNLVLILTMKRLQMAGHKPYALVGGATGLIGDPSFKDSERSLQTKDTVTKWSGKIRSQLERFLDFENGENKAEMTNNYNWFENLTFIDFLRDVGKHFTVNYMISKDSVKSRMESGISYTEFAYQIMQGYDFYELNQLHNVTLQLGGSDQWGNMTAGTELLRRKANKQGHVITIPLITDSTGKKFGKSEGNAIWLDADKTSPYEMYQFWLNVDDADAVKMLKIFTFLSLEEIAEIEEQFEAARHERLAQKVLAREVVSLVHGKEAYEQAVKTSEILFGGGDLRQLDAKSILTGLKAAPQHQIAPDEDLTLIELLISVGIAPSKRQAREDITNGAIYINGERVQELDYVLTDSDKIENRLTVIRRGKKKNFVLTY
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_PARL1
Sequence: MAPTPDRDGQDKKVCLGVVTGAHGVRGLVRVKPYTEMPEGVAAYGPVETKDGATSFAISLKGMAKDLVICKLEGVDDRDVAAALRGTELYVPRERLPRASGDEEGWYYADLIGLRAVGLDGRDYGRIAGVENFGAGDLLEIAPAEGGQTVLMGFTDENVPEVDIAGGRVVIDPPAGTFGDDAEAERGE
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSOP1_ARATH
Sequence: MAEEAKAKGNAAFSSGDFTTAINHFTEAIALAPTNHVLFSNRSAAHASLHQYAEALSDAKETIKLKPYWPKGYSRLGAAHLGLNQFELAVTAYKKGLDVDPTNEALKSGLADAEASVARSRAAPNPFGDAFQGPEMWTKLTSDPSTRGFLQQPDFVNMMQEIQKNPSSLNLYLKDQRVMQSLGVLLNVKFRPPPPQGDEAEVPESDMGQSSSNEPEVEKKREPEPEPEPEVTEEKEKKERKEKAKKEKELGNAAYKKKDFETAIQHYSTAIEIDDEDISYLTNRAAVYLEMGKYNECIEDCNKAVERGRELRSDYKMVARALTRKGTALTKMAKCSKDYEPAIEAFQKALTEHRNPDTLKRLNDAERAKKEWEQKQYFDPKLGDEEREKGNDFFKEQKYPEAIKHYTEAIKRNPNDHKAYSNRAASYTKLGAMPEGLKDAEKCIELDPTFSKGYSRKAAVQFFLKEYDNAMETYQAGLEHDPSNQELLDGVKRCVQQINKANRGDLTPEELKERQAKGMQDPEIQNILTDPVMRQVLSDLQENPSAAQKHMQNPMVMNKIQKLISAGIVQMK
What is the function of this protein?
Mediates the association of the molecular chaperones HSP70 and HSP90.  Mediates nuclear encoded chloroplast preproteins binding to HSP90 prior to chloroplastic sorting (By similarity).
What are the official names of this protein?
Hsp70-Hsp90 organizing protein 1, AtHop1, Stress-induced-phosphoprotein 1, STI1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: METJ_ESCF3
Sequence: MAEWSGEYISPYAEHGKKSEQVKKITVSIPLKVLKILTDERTRRQVNNLRHATNSELLCEAFLHAFTGQPLPDDADLRKERSDEIPEAAKEIMREMGINPETWEY
What is the function of this protein?
This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.
What are the official names of this protein?
Met repressor, Met regulon regulatory protein MetJ.
What is the protein family that this protein belongs to?
Belongs to the MetJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYK_MYCPN
Sequence: MSDRLNDQAQNRLQKLLNLKQTGNDPYLITKIENTHSAASFQKAFANQSDAELKQYQVILTGRIIALRQTFIIIQDFSGKMQLYINKKTAPELFEYFNNYIDLGDQIVATGHPMMTKTGVLTLNVERLQIVAKCLQTPPEKWHGLTDPEARARKRYLDLTYNRAQVEVFLKRTQIITAIRTFLNEAGFLEVETPILQAVLGGANAKPFKTHYNALKGDFYLRIANEIALKKLIVGGLPKVYEMGRMFRNEGVDTTHNPEFTSIEMYQANADYAVMMDLTENLIKFVCKTLNQWSFNWNGQTLDLAKPFKKVKMVDLICQVTGVNFDDVKDDQTAIALAKQHKVELKKHEQNKQHIINRFFEQFCEHTLIQPTFVTHYPKAVSPLAKQDPHNPEFTERFELFINTKELANAYSELNDPLEQRARFEQQLQEKRMGNDEASELDESFLDALSFGLPPTGGLGIGVDRLVMLLCECSSIRDVVFFPQLRELK
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y9684_DICDI
Sequence: MKSNNKNLEIEIITIFYTNLISRTIYIPASSNSSGSSGLFASSGSFDSFGYFF
What are the official names of this protein?
Putative uncharacterized protein DDB_G0267970.
Protein: RS3_ALDYE
Sequence: MGQKSNPNGLRLGIIRTWESKWYDVDKKVPFLVGEDFKIRTLIKNNYPKSTISQIEIKRLKKSNDEFIEIDLYTSKIGIIQGPENKNKNSLINKIEKLINKKVQINIFEVKAINKIAVLVAQNIAIQLQQRAFYKAVLKSAIQKALKSGIKGIKIIITGRLGGAEKARRDSISMGVVPLNTLRADIDYAFEEAHTTYGVLGVKVIINHGEVLPNKTIADTRQIFSSQYENKKNNNKRHFVDKKNFKKSTS
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: Y1012_METTP
Sequence: MRIIGFVGMPGSGKSVASDVAREMGIRVVVMGDVVRAEARRRGLEPTDANHGMVGDELRRSEGEDAIARRCLEGLSRDETIVVDGIRSGAEVEYFRSVADRFHLIEIFTPPEQRLRRIAARGRSDDNNCGDLSEALERRDARELGWGMGEAIAAAGMRICNDCTLDEFRERIRVVLEELCRS
What are the official names of this protein?
UPF0200 protein Mthe_1012.
What is the protein family that this protein belongs to?
Belongs to the UPF0200 family.
Protein: Y6549_BACAN
Sequence: MHHIGYEVLQETFVLIRNVFSYSNQGEYSVTYVREIADALYNIPHSIQKQHDTFLEFEFKLLEETLMQMEFGKVAAQNIPHFRMYAARVQQLLRKRYKEV
What are the official names of this protein?
Uncharacterized protein pXO2-44/BXB0049/GBAA_pXO2_0049.
Protein: URE1_BACC1
Sequence: MSFKMSRKQYADLYGPTTGDSIRLADTQLFAHIERNATVYGDEAVFGGGKSIRDGMGQNSQLTREQGVVDVVITNAIIIDYTGIYKADIGIKDGKISAIGKSGNPSVMDNIDIIIGTSTEVISGERKIVTAGGIDTHVHFISPQQIDTALASGITTLIGGGTGPAEGTKATTITPGSWNLRKMLEAAEAFPINLGFLGKGNSSSLPALEEQIFAGAIGLKIHEDWGATSSAINHSLQIADKYDIQVAIHTDTLNECGFVEETIKAIDNRVIHTYHTEGAGGGHAPDIIKIAALNNILPSSTNPTLPYTVNTLDEHLDMLMVCHHLKANIPEDVMFADSRIRKETIAAEDILQDLGVFSMISSDSQAMGRVGEVIIRNWQTADKMKKQIGSLEGDKEYNDNNRIQRYIAKYTINPAITHGISEYVGSIEVGKYADLVIWDPQFFGVKPDMVLKNGMVVMALMGDENASIPTPQPYYEKKMFGAYGKAVQSSSITFVSKVAYENNIKDKLGLNKVVLPVKNTREISKQDMKLNNATPEIEVDPQTYEVKVDGKVITCEAVDVLPMAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPP_BURP1
Sequence: MKQDSRFPNLFILDHPLIQHKLTHMRDKDTSTRTFRELLREITLLMGYEITRNLPITTKRVETPLVEIDAPVIAGKKLAIVPVLRAGVGMSDGLLELIPSARVGHIGVYRADDHRPVEYLVRLPDLEDRIFILCDPMVATGYSAAHAIDVLKRRGVPGERLMFLALVAAPEGVQVFQDAHPDVKLYVASLDSHLDDHAYIVPGLGDAGDRLFGTKN
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: RUTB_ECOL6
Sequence: MPRPSPCADSGGGMMTTLTARPEAITFDPQQTALIVVDMQNAYATPGGYLDLAGFDVSTTRPVIANIQTAVTAARTAGMLIIWFQNGWDEQYVEAGGPGSPNFHKSNALKTMRNQPQLQGKLLAKGSWDYQLVDELVPQPGDIVLPKPRYSGFFNTPLDSILRSRGIRHLVFTGIATNVCVESTLRDGFFLEYFGVVLEDATHQAGPEFAQKAALFNIETFFGWVSDVETFCDALSSTSFARIA
What is the function of this protein?
Hydrolyzes ureidoacrylate to form aminoacrylate and carbamate.  The carbamate hydrolyzes spontaneously, thereby releasing one of the nitrogen atoms of the pyrimidine ring as ammonia and one of its carbon atoms as CO2.
What are the official names of this protein?
Ureidoacrylate amidohydrolase RutB.
What is the protein family that this protein belongs to?
Belongs to the isochorismatase family. RutB subfamily.
Protein: AROK_VIBC1
Sequence: MAEKRNIFLVGPMGAGKSTIGRHLAQQLHMEFVDSDTVIEERTGADIAWVFDVEGEEGFRKREEAVLEDLTQEQGIVLATGGGSVKSKENRNRLSARGVVVYLETTIEKQLARTNRDKKRPLLQTDNPREVLESLAGERNPLYEEVADYTVRTDDQSAKVVANQIVKMLEER
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y434_METJA
Sequence: MRKDVKIYLNHILESIELIEEYTKDKTEDDFFTSKFLQDAVIRRIEIIGEAIKNLPMEFREKYNHIPWKEFAEMRDILIRKYFGVDLGLTWEVVKKDIPKLKEEILKIMEELDKNKNNKYNVFAYGELMKKERLLELINRVPKMIEGRVYGYEKFFDETIGYYGARKKEGSYIDGIILLDITDKELGIFDDYEDLDVYYIREKTTAVSEDGRKYDVYIYLRK
What is the function of this protein?
Probable toxic component of a putative type VII toxin-antitoxin (TA) system, probably an RNase.  Probably neutralized by cognate antitoxin MJ0435.  Neutralization may be due to AMPylation by MJ0435.
What are the official names of this protein?
Gamma-glutamylcyclotransferase and putative RNase MJ0434.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the gamma-glutamylcyclotransferase family.
Protein: BIOD_CLOPE
Sequence: MEKGVYIIGTNTDIGKTFISGLILKKLREEGRNAGYYKAVLSGAIKEKNGLIPLDCEEVMKISGLKESYENMVSYILENPYSPHLASEVEEVSISMEKIKKDYKSVRDKYDFILCEGSGGIVCPISFSEKKLMLEDIIKEFNLQIILVSNSGLGTINYTVLTVSYLRNLGLKVKGIILNKFNKSDIIHRDNKKIIKELTGVNNISTVPKIEDIEKYDLNELNEVLYGI
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_NITWN
Sequence: MNIIQQLEKEQFDKLSATKTIPEFGPGDTVIVNVKVVEGERTRVQAYEGVCIGRSGGGLNESFTVRKISYGEGVERVFPVMSPMIDSIKVVRRGKVRRAKLYYLRKLRGKSARIVEKKTDRAAATN
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: MA2A2_HUMAN
Sequence: MKLKKQVTVCGAAIFCVAVFSLYLMLDRVQHDPTRHQNGGNFPRSQISVLQNRIEQLEQLLEENHEIISHIKDSVLELTANAEGPPAMLPYYTVNGSWVVPPEPRPSFFSISPQDCQFALGGRGQKPELQMLTVSEELPFDNVDGGVWRQGFDISYDPHDWDAEDLQVFVVPHSHNDPGWIKTFDKYYTEQTQHILNSMVSKLQEDPRRRFLWAEVSFFAKWWDNINVQKRAAVRRLVGNGQLEIATGGWVMPDEANSHYFALIDQLIEGHQWLERNLGATPRSGWAVDPFGYSSTMPYLLRRANLTSMLIQRVHYAIKKHFAATHSLEFMWRQTWDSDSSTDIFCHMMPFYSYDVPHTCGPDPKICCQFDFKRLPGGRINCPWKVPPRAITEANVAERAALLLDQYRKKSQLFRSNVLLVPLGDDFRYDKPQEWDAQFFNYQRLFDFFNSRPNLHVQAQFGTLSDYFDALYKRTGVEPGARPPGFPVLSGDFFSYADREDHYWTGYYTSRPFYKSLDRVLEAHLRGAEVLYSLAAAHARRSGLAGRYPLSDFTLLTEARRTLGLFQHHDAITGTAKEAVVVDYGVRLLRSLVNLKQVIIHAAHYLVLGDKETYHFDPEAPFLQVDDTRLSHDALPERTVIQLDSSPRFVVLFNPLEQERFSMVSLLVNSPRVRVLSEEGQPLAVQISAHWSSATEAVPDVYQVSVPVRLPALGLGVLQLQLGLDGHRTLPSSVRIYLHGRQLSVSRHEAFPLRVIDSGTSDFALSNRYMQVWFSGLTGLLKSIRRVDEEHEQQVDMQVLVYGTRTSKDKSGAYLFLPDGEAKPYVPKEPPVLRVTEGPFFSEVVAYYEHIHQAVRLYNLPGVEGLSLDISSLVDIRDYVNKELALHIHTDIDSQGIFFTDLNGFQVQPRRYLKKLPLQANFYPMPVMAYIQDAQKRLTLHTAQALGVSSLKDGQLEVILDRRLMQDDNRGLGQGLKDNKRTCNRFRLLLERRTVGSEVQDSHSTSYPSLLSHLTSMYLNAPALALPVARMQLPGPGLRSFHPLASSLPCDFHLLNLRTLQAEEDTLPSAETALILHRKGFDCGLEAKNLGFNCTTSQGKVALGSLFHGLDVVFLQPTSLTLLYPLASPSNSTDVYLEPMEIATFRLRLG
What is the function of this protein?
Catalyzes the first committed step in the biosynthesis of complex N-glycans.  It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway.
What are the official names of this protein?
Alpha-mannosidase 2x, Alpha-mannosidase IIx, Man IIx, Mannosidase alpha class 2A member 2, Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 38 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: HIS2_LISIN
Sequence: MLSDLYEEIKLRKTQPKEGSYTNYLFEKGLDKILKKVGEETTEVVIAAKNNNEELISEITDLTYHLLVLLAEKDIPLEDIKQELQSREGKLSKTSDRKEINDL
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DID5B_MACLO
Sequence: MNSANPCCDPITCKPRRGEHCVSGPCCRNCKFLNPGTICKRTMLDGLNDYCTGVTSDCPRNPWKSEEED
What is the function of this protein?
Poor inhibitor of platelet aggregation.  The disintegrin inhibits the adhesion of the alpha-4/beta-1 (ITGA4/ITGB1) integrin to VCAM-1.  Inhibition on alpha-2b/beta-3 (ITGA2B/ITGB3) is low.
What are the official names of this protein?
Disintegrin VLO5B.
What is the protein family that this protein belongs to?
Belongs to the disintegrin family. Dimeric disintegrin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: KDKA_VIBPA
Sequence: MIQQYRDSNQVIWFDEELIEDPSQPIFDAEYWQSTNKVTGSASGRGTTWFVQLDTMQAALRHYRRGGLFGKLVKDNYLFSGWEQTRCAQEFQLLLTLINAGVHVPRPIAARAVKSGLTYQADLLSERIPNARDLVSILQEKPLPEGMYQKIGQEIAKMHNAGVNHTDLNIHNILIDDKDKVWIIDFDKCRKQEHGDWKKQNLERLLRSFKKELLKRQIHWKERDFAVLTEALSCLDIK
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position.
What are the official names of this protein?
3-deoxy-D-manno-octulosonic acid kinase, Kdo kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. KdkA/RfaP family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.