PharMolix/UniProtQA huggingface dataset:
Protein: LAMB_SALDC
Sequence: MMITLRKLPLAVAVAAGVMSAQAMAVDFHGYARSGIGWTGSGGEQQCFQATGAQSKYRLGNECETYAELKLGQEVWKEGDKSFYFDTNVAYSVNQQNDWESTDPAFREANVQGKNLIEWLPGSTIWAGKRFYQRHDVHMIDFYYWDISGPGAGIENIDLGFGKLSLAATRSTEAGGSYTFSSQNIYDEVKDTANDVFDVRLAGLQTNPDGVLELGVDYGRANTTDGYKLADGASKDGWMFTAEHTQSMLKGYNKFVVQYATDAMTTQGKGQARGSDGSSSFTEELPDGTKINYANKVINNNGDMWRILDHGAISLGDKWDLMYVGMYQNIDWDNNLGTEWWTVGVRPMYKWTPIMSTLLEVGYDNVKSQQTGDRNNQYKITLAQQWQAGDSIWSRPAIRIFATYAKWDEKWGYIKDGDNISRYAAATNSGISTNSRGDSDEWTFGAQMEIWW
What is the function of this protein?
Involved in the transport of maltose and maltodextrins.
What are the official names of this protein?
Maltoporin, Maltose-inducible porin.
What is the protein family that this protein belongs to?
Belongs to the porin LamB (TC 1.B.3) family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: PPAC_STRSV
Sequence: MSKILVFGHQNPDSDAIGSSYAFAYLAREAYGLDTEVVALGEPNEETAFVLDYFGVAAPRVITSAKAEGAEQVILTDHNEFQQSVADIAEVEVYGVVDHHRVANFETASPLYMRLEPVGSASSIVYRMFKEHGVEVPKEIAGLMLSGLISDTLLLKSPTTHPTDKVIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRVAQVNTVDIAEVLERQAEIEAAIEKAIADNGYSDFVLMITDIINSNSEILAIGSNMDKVEAAFNFVLENNHAFLAGAVSRKKQVVPQLTASFSA
What are the official names of this protein?
Probable manganese-dependent inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase class C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VM38_CROAD
Sequence: MIQVLLVTICLAVFPYQGSSIILGSGNVNDYEVVYPRKVTALPKGAAQPKYEDTMQYEFKVNGEPVVLHLEKNKGLFSEDYSETHYSPDGREITTYPPVEDHCYYHGRIQNDADSTASISACNGLKGHFKLQGEMYLIEPLELSDSEAHAVFKYENVEKEDEAPKMCGVTQNWESYEPIKKASQLNLTPEQQRYLNTKKYIELVIVADNVMVKKYTSNSTAIRTRIYACVNTLNLIYRAFNIHIALVGIEIWSNGDLINVTSAANVTLDLFGNWRRRVLLRHKRHDNAQLLTAIDFDGPTVGLAYGASMCDPRFATGIVQDHSKLDIMVAVTMAHELGHNLGMNHDGNQCNCGGNPCIMSATLNFEPAYQFSDCSRDEHWRYLIDNRPPCILNKPSITDIVSPPVCGNYFVEVGEECDCGLPARCQNPCCNAATCKLRPGTQCEDGECCEQCQFKGAGTECRAASSECDIAESCTGQSADCPTDDFQRNGQPCLNNNGYCYNGTCPTLDDQCISFFGSSKTVAPDVCFNLNLQGQGDFYCRRENTRIFPCAPQDKKCGRLFCVLGPTGNTISCQSTYSQSDLDIGMVDLGTKCGDGRVCNSTRQCVDVNTAY
What is the function of this protein?
Snake venom metalloproteinase that impairs hemostasis in the envenomed animal.
What are the official names of this protein?
Zinc metalloproteinase-disintegrin-like 8, Snake venom metalloproteinase, SVMP.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-III subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPF_PINTH
Sequence: MKNVIDPFISLSYWPSAGGFGSNTNILETNIINSSVVLSVLIYFGKGVLSNLLDNRKQKILETIRNSEELCKGAIDQLEKARACLRNVEMIADEIQVNGNSQIEREKEDLLNTASDNLEQLEDPKNETIYSEQQRAFDQIRQQVSRQALRRAIGTLNSRLNTELHLRTIDHNIGLLRTMMNTND
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, chloroplastic, ATP synthase F(0) sector subunit b, ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: AEP2_ZYGRC
Sequence: MLRTACSRSHVFKAFSSSLMLEHALAAANSSGAAAPTNAASTGNSHDSTLKSELPLRTLNDELHNAERKYIKPLTNAPEWSSTRTGPNSKIREYLKNGQYTKLLIRLSVDNHLNNEYISGLFTTGGLTKSEYSLFINKLLSEEELDVKLSNVIPDTPHTELIYKLYEFYCDHIVDQHNLTPLQLYDLNLFLKTFIAEAQLSKAHNVLDFILLRRPLNDLLANTDVEILIQFLRLKCGALSKFWKIQPASQRNSTAITLGEKASDCHLAKSYKFQNEKVLLQIINSVLGEHNWKNRRSPKLDAAIIYSLGYLGQTDLIEKYVNRTWSPSKDEGVKTNPNSDLLVAVLTSYCVKEGNMRKGLEVLDRFIRDYPEVELDPLFWRRLLQLSSLLWDKKRDRKATLSHGCWTIMKQWHAQRQRKIPYDYGIMKELYPIFVRTKNKNGALEVITKSFFGAFIQPEFTIRPNELSLLCKYQRFILKMIALKGNYHKGFEFCQEWSFSSTNKFELQSYFMKWRGIHEQRRTSQSKQKAALQEKYDEMEEDDMLLGRLW
What is the function of this protein?
Required for translation of the mitochondrial OLI1 transcript coding for the mitochondrial ATP synthase subunit 9.
What are the official names of this protein?
ATPase expression protein 2, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AEP2 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RF1_COREF
Sequence: MAGHVSAVDDILAEYHGLEEQMADPALHNDPAAARRVGKRYSELQPIINVHRQLVQVRDDLEAAREMAHEDHEFAAEAERLEVELVELEEKLADLLAPRDEHDGDDIVMEIKAGAGGEEAALFAGDLLRMYQKYADKHGFIIEVLDSAESDLGGVKDITLSIRSRQPSRDGAWSQFKFEGGVHRVQRVPVTESQGRIQTSAAGVLVYPEPDEVEDVEIDEKEIRVDVYRSSGKGGQGVNTTDSAVRITHLPTGIVVTCQKERSQIQNRARAMQVLAARLQALQKEEADAEAAEGRASQIRTMDRSERIRTYNWPENRISDHRIGFKANNLDAVLNGELDDLFTALRAAERAERLEADN
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_EXISA
Sequence: MAKKVSKLVKLQIPAGKANPAPPVGPALGQAGVNIMGFCKEFNARTQDQAGLIIPVVITVYEDRSFTFITKTPPAAVLLKKAAGIESGSGEPNRKKVATVKRDKVREIAELKMPDLNASSVETAMLMVEGTARSMGIVIED
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RR3_VITVI
Sequence: MGQKINPLGFRLGTTQGHHSLWFAQPKNYSKGLQEDQKIRDCIKNYVQKNIRISSGVEGIARIEIQKRIDLIQVIIYMGFPKLLVEGKPRRIEELQMNVQKELNYVNRKLNIAITRITKPYGHPNILAEFIAGQLRNRVSFRKAIKKAIELTEQADTKGIQVQIAGRIDGKEIARVEWIREGRVPLQTIRAKIDYCSYRVRTIYGVLGIKIWIFVDEE
What are the official names of this protein?
30S ribosomal protein S3, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FA20C_HUMAN
Sequence: MKMMLVRRFRVLILMVFLVACALHIALDLLPRLERRGARPSGEPGCSCAQPAAEVAAPGWAQVRGRPGEPPAASSAAGDAGWPNKHTLRILQDFSSDPSSNLSSHSLEKLPPAAEPAERALRGRDPGALRPHDPAHRPLLRDPGPRRSESPPGPGGDASLLARLFEHPLYRVAVPPLTEEDVLFNVNSDTRLSPKAAENPDWPHAGAEGAEFLSPGEAAVDSYPNWLKFHIGINRYELYSRHNPAIEALLHDLSSQRITSVAMKSGGTQLKLIMTFQNYGQALFKPMKQTREQETPPDFFYFSDYERHNAEIAAFHLDRILDFRRVPPVAGRMVNMTKEIRDVTRDKKLWRTFFISPANNICFYGECSYYCSTEHALCGKPDQIEGSLAAFLPDLSLAKRKTWRNPWRRSYHKRKKAEWEVDPDYCEEVKQTPPYDSSHRILDVMDMTIFDFLMGNMDRHHYETFEKFGNETFIIHLDNGRGFGKYSHDELSILVPLQQCCRIRKSTYLRLQLLAKEEYKLSLLMAESLRGDQVAPVLYQPHLEALDRRLRVVLKAVRDCVERNGLHSVVDDDLDTEHRAASAR
What is the function of this protein?
Golgi serine/threonine protein kinase that phosphorylates secretory pathway proteins within Ser-x-Glu/pSer motifs and plays a key role in biomineralization of bones and teeth (PubMed:22582013, PubMed:23754375, PubMed:25789606).  Constitutes the main protein kinase for extracellular proteins, generating the majority of the extracellular phosphoproteome (PubMed:26091039).  Mainly phosphorylates proteins within the Ser-x-Glu/pSer motif, but also displays a broader substrate specificity (PubMed:26091039).  Phosphorylates ERO1A, enhancing its activity which is required to maintain endoplasmic reticulum redox homeostasis and for oxidative protein folding (PubMed:29858230, PubMed:34349020).  During endoplasmic reticulum stress, phosphorylates P4HB/PDIA1 which induces a functional switch, causing P4HB to change from an oxidoreductase to a molecular chaperone (PubMed:32149426).  This is critical to maintain ER proteostasis and reduce cell death under ER stress (PubMed:32149426).  Phosphorylation of P4HB also promotes its interaction with ERN1, leading to reduced activity of ERN1, a key sensor for the endoplasmic reticulum unfolded protein response (PubMed:32149426).  Required for osteoblast differentiation and mineralization (PubMed:34349020).  Phosphorylates casein as well as a number of proteins involved in biomineralization such as AMELX, AMTN, ENAM and SPP1/OPN (PubMed:22582013, PubMed:25789606, PubMed:34349020).  In addition to its role in biomineralization, also plays a role in lipid homeostasis, wound healing and cell migration and adhesion (PubMed:26091039).
What are the official names of this protein?
Extracellular serine/threonine protein kinase FAM20C, Dentin matrix protein 4, DMP-4, Golgi casein kinase, Golgi-enriched fraction casein kinase, GEF-CK.
What is the protein family that this protein belongs to?
Belongs to the FAM20 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein. Secreted. Endoplasmic reticulum. Note=Resides in the Golgi apparatus membrane and is secreted following propeptide cleavage (PubMed:34349020). Retained in the endoplasmic reticulum (ER) in response to ER stress where it phosphorylates P4HB (PubMed:32149426).
Protein: RL34_ALISL
Sequence: MKRTFQPSVLKRKRSHGFRARMATKNGRNTINARRAKGRKRLSK
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: COXX_GRABC
Sequence: MSDSAFVNGGREVSSLPLSAQMPGMASAADWVTLLKPRVMSLVVFTGLIGMLVAPGSLHPVLGAIAILCIAVATGASGAINMWYDRDIDAVMRRTKNRPIPAGRIEPGEALGYGIVLAVGSVLVMWLATNVVAAAVLAFAIFFYSVIYTMWLKRSTPQNIVIGGAAGAFPPVIGWAAVTGTIDLMPVMMFAIVFFWTPPHFWSLSLWAQMDYERAGVPMLPVVAGARKTRQHIMAYTVLLSVIAVLPWALGDTGRVYGLSAVVLSLGFLVQSWRVLRDKQDEVGLSLTKDAPARAAFKYSLIYLAVLFLALAVDRFV
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL28_ACIBC
Sequence: MSKVCQVTGKRPVVGNNVSHANNKTKRRFEPNLHHHRFWLESEKRFVRLRLTTKGMRIIDKLGIEKVVADLRAQGQKI
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: DEOB_SYMTH
Sequence: MAAVRRVVLIVIDSVGIGAMPDAADWGDAGANTLGNMARQRGGLPLPNLGRLGLGNLCAIEGTPPVDAPAGAYGRMAIFSHGKDTMTGHWEMVGIRPEAPFRTYPDGFPEDLIAEFCRRAGLEGVLGNKVASGTEIIKELGEEHLRTGWPIVYTSADSVFQVAAHEERFGLERLYEVCRIARDLLRPPHRVGRVIARPFVGTDRTNFTRTANRHDYALEPPRMLLDEVKDAGLSVLAVGKISDIFSGHGITYSVHTKSNADGIEKIHECLDRQEPGLIFANLVDFDMLYGHRRDVEGYARAMLEFDAALPAIMAKLGPEDVLVVTADHGNDPTYIGTDHTREYVPVLLYGEPIKPGVDVGTRASLADLGATVADLLGVPQTGFGESFADQIRK
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_LEGPL
Sequence: MSRVCQVTGKRPMVGHKVSHANNKTKRRFLPNIQNHKFWVEEENRFVTLRLSTKGMRIIDKLGIKAVLDKIRAKGEKI
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: RS7_ACIC1
Sequence: MPRKGPAPKRPIVSDPVYGSPLVTALINKVLQRGKRSLAERIVYNALEGCRARTGTDPLITLKRALDNVRPTLEVRSRRVGGATYQVPVEVRPQRSTSLALRWIVHYAKLRREKTMIERLTNELLDASNGLGASVKRREDTHKMAESNRAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: SARZ_STAAM
Sequence: MYVENSYLSKQLCFLFYVSSKEIIKKYTNYLKEYDLTYTGYIVLMAIENDEKLNIKKLGERVFLDSGTLTPLLKKLEKKDYVVRTREEKDERNLQISLTEQGKAIKSPLAEISVKVFNEFNISEREASDIINNLRNFVSKNFDYSDRK
What is the function of this protein?
Activates transcription of virulence factors alpha- and beta hemolysin genes (hla and hlb).  Also, activates RNAIII expression, a central regulator transcribed from the agr locus (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator SarZ, Staphylococcal accessory regulator Z.
What is the protein family that this protein belongs to?
Belongs to the SarZ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DF131_ARATH
Sequence: MAKNRVLTIFYCTIYYCICFKYVLLGMVVEKTQGHICHDYLEGDHCDPKDCNLDCRDKWKGTGTCEPPTGTPLTRTCYCTYDC
What are the official names of this protein?
Putative defensin-like protein 131, Putative low-molecular-weight cysteine-rich protein 29, Protein LCR29.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: ISPG_BACAC
Sequence: MNEMTHRTKTRPVKVGNLTIGGNNELIIQSMTTTKTHDVEATVAEIKRLEEAGCQVVRVAVPDERAANAIADIKKQINIPLVADIHFDYRLALKAIEGGIDKVRINPGNIGRRHKVEAVVNAAKERGIPIRIGVNAGSLERHILEKYGYPTADGMVESALHHIKILEDLDFHDIIVSMKASDVNLAIEAYEKAARAFDYPLHLGITESGTLFAGTVKSAAGLGAILNKGIGNTLRISLSADPVEEVKVARELLKSFGLASNAATLISCPTCGRIEIDLISIANEVEEYISTLQVPIKVAVLGCAVNGPGEAREADIGIAGARGEGLLFRKGQVVRKVPEEIMVEELKKEIDVIAAEMAAEREKEKETQEQ
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: YKD6_YEAST
Sequence: MCFGVLLSGHYYVMVHLLWKLYYIIGRGLGLLTLLMWKEPEIESPTPKTVTSISWYLLEELCCLFRFIYSIQNRERKCKNGPSPNKRGSASGCSRRGGGRGSGYKTLYRDLCENKPTPELWTLQAPELNL
What are the official names of this protein?
Putative uncharacterized protein YKL036C.
Protein: GJ_HHV11
Sequence: MSLRAVWHLGLLGSLVGAVLAATHRGPAANTTDPLTHAPVSPHPSPLGGFAVPLVVGGLCAVVLGAACLLELLRRTCRGWGRYHPYMDPVVV
What is the function of this protein?
Inhibits host cell apoptosis.  Induces an increase in reactive oxygen species (ROS) in the host cell.
What are the official names of this protein?
Envelope glycoprotein J.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae glycoprotein J family.
What are the subcellular locations of this protein?
Host Golgi apparatus membrane; Single-pass type I membrane protein. Host endoplasmic reticulum membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein.
Protein: PYC1_YEAST
Sequence: MSQRKFAGLRDNFNLLGEKNKILVANRGEIPIRIFRTAHELSMQTVAIYSHEDRLSTHKQKADEAYVIGEVGQYTPVGAYLAIDEIISIAQKHQVDFIHPGYGFLSENSEFADKVVKAGITWIGPPAEVIDSVGDKVSARNLAAKANVPTVPGTPGPIETVEEALDFVNEYGYPVIIKAAFGGGGRGMRVVREGDDVADAFQRATSEARTAFGNGTCFVERFLDKPKHIEVQLLADNHGNVVHLFERDCSVQRRHQKVVEVAPAKTLPREVRDAILTDAVKLAKECGYRNAGTAEFLVDNQNRHYFIEINPRIQVEHTITEEITGIDIVAAQIQIAAGASLPQLGLFQDKITTRGFAIQCRITTEDPAKNFQPDTGRIEVYRSAGGNGVRLDGGNAYAGTIISPHYDSMLVKCSCSGSTYEIVRRKMIRALIEFRIRGVKTNIPFLLTLLTNPVFIEGTYWTTFIDDTPQLFQMVSSQNRAQKLLHYLADVAVNGSSIKGQIGLPKLKSNPSVPHLHDAQGNVINVTKSAPPSGWRQVLLEKGPAEFARQVRQFNGTLLMDTTWRDAHQSLLATRVRTHDLATIAPTTAHALAGRFALECWGGATFDVAMRFLHEDPWERLRKLRSLVPNIPFQMLLRGANGVAYSSLPDNAIDHFVKQAKDNGVDIFRVFDALNDLEQLKVGVDAVKKAGGVVEATVCFSGDMLQPGKKYNLDYYLEIAEKIVQMGTHILGIKDMAGTMKPAAAKLLIGSLRAKYPDLPIHVHTHDSAGTAVASMTACALAGADVVDVAINSMSGLTSQPSINALLASLEGNIDTGINVEHVRELDAYWAEMRLLYSCFEADLKGPDPEVYQHEIPGGQLTNLLFQAQQLGLGEQWAETKRAYREANYLLGDIVKVTPTSKVVGDLAQFMVSNKLTSDDVRRLANSLDFPDSVMDFFEGLIGQPYGGFPEPFRSDVLRNKRRKLTCRPGLELEPFDLEKIREDLQNRFGDVDECDVASYNMYPRVYEDFQKMRETYGDLSVLPTRSFLSPLETDEEIEVVIEQGKTLIIKLQAVGDLNKKTGEREVYFDLNGEMRKIRVADRSQKVETVTKSKADMHDPLHIGAPMAGVIVEVKVHKGSLIKKGQPVAVLSAMKMEMIISSPSDGQVKEVFVSDGENVDSSDLLVLLEDQVPVETKA
What is the function of this protein?
Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
What are the official names of this protein?
Pyruvate carboxylase 1, Pyruvic carboxylase 1, PCB 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOR_MANSE
Sequence: MKLTSLFIFVIVALSLLFSSTDAAPGKIPVKAIKQAGKVIGKGLRAINIAGTTHDVVSFFRPKKKKH
What is the function of this protein?
Antimicrobial peptide.  Active against a broad spectrum of Gram-positive and Gram-negative bacteria including methicillin-resistant S. aureus ATCC 43 300, S. aureus BAA-39, pathogenic strains of L. monocytogenes, K. pneumoniae, E. coli O157:H7, S. typhimurium and multidrug-resistant S. typhimurium DT104 with minimum inhibitory concentration (MIC) of 1. 4 uM for all except for S. aureus BAA-39 (PubMed:18265434).  Also active against Serratia marcescens (PubMed:14728663).  Probably acts by disturbing membrane functions with its amphipathic alpha-helical structure (PubMed:18265434).  May protect a developing embryo from bacterial infection (Probable).
What are the official names of this protein?
Moricin.
What is the protein family that this protein belongs to?
Belongs to the moricin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PDXB_COLP3
Sequence: MKIYFDENMPFAKEFFSELCHLNNGIDGEEQGELVPFSGRTLTAAQVADADVLLVRSITQVNEQLLHLNDKISFVGSATIGTDHIDLSYLAKRNITFQSAPGCNAISVAEYVLSALVVLAERYLLTLSSLTVGIVGGGNTGTRLSEKLTALGIQHKICDPLLAEKQKQDKSHPPTDQRHYVPLVDVLACDVISLHVPKVVGGEHPTNKLINAENLALLREDQILISACRGDVIDNHALLALKTAGHGVKIVLDVWQGEPDVLEALIPYTEIATAHIAGYSLEGKARGSEMLYQALCQQLAITPKYQLANFLPSASIPAIEINQDFNQILLNQLVKMVYDVRRDDAIFRQQLFVQGFDSLRKNYPVRREFSAVTVNLSSTTYSDVPHRLGFNKN
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROA_NITEU
Sequence: MQWLDLPHVQRAQGNVRLPGSKSISNRILLLSALAEGTTMVSNLLESDDTGRMLDALRLLGVAIVRTDDGKYRVAGCKGKFPVREAELFLGNAGTAFRPLTAVLALMQGHYRLSGVPRMHERPIGDLVDALRQIGAVITCLEHEGFPPLEIHPAVIRPGNISIKGNISSQFLSGLLMALPLTGEPVTIVVSGTLISQPYVALTIAQMARFGVQVKQESWQRFMLPENQTYRSPGKIAVEGDASSASYFLAAGAIAGGPVRIEGAGSDSCQGDIRFVEALEAMGARISMGSDWIESGAPDGGALKAIDFDCNHIPDAAMTLATMALFARGTTTLRNIASWRVKETDRIAAMSAELRKLGARVEAGDDFLRITPPDGPLTADAVIDTYDDHRMAMCFSLVSLSVPVRINDPGCVAKTFPDYFEKFAAITHTPF
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T2C2_PBCV1
Sequence: MTQKILNPVTGRFVKVDGSTGKKIKTGNIYDVNNILSSKLTKKIFDKIRRNDLAKEERETQQLTKKISKGIFDKIRSENKKYEKNHQKLTKKMVLDIFSKIYKEDSRKSKTQCVVSEKKDNGGVLLTEDLGKIFEKSICMLYDTPYIGPYKYGNEKPMLLKTRLHKLLDFFPELTHTAAGGALHDFTTKNSRYLSAKTSKKKDGKVAPQKIGQPTKKKFLEFFNLPPDTSNDDIKLFIKKNIVRILDEYFKYTFDDTIIYYNEVNNIIMLVKTLKKVKFDPNLIEFGCNKPGKSWKESTILFYNNKRLGEFQIHTSRSCIKFRWFFENILLLFPDNFEVTIL
What is the function of this protein?
A P subtype restriction enzyme that recognizes the double-stranded sequence 5'-CATG-3' and cleaves after C-1.
What are the official names of this protein?
Type II restriction enzyme CviAII, R.CviAII, Endonuclease CviAII, Type-2 restriction enzyme CviAII.
Protein: PGK_AERS4
Sequence: MSVIKMTDLDLAGKRVLIRADLNVPVKDGKVTSDARIVATLPTIKLALEKGAKLMITSHLGRPTEGEYNEEFSLAPVVNYLKDALSCPVRLAKDYLDGVDVAAGELVVLENCRFNKGEKKNTEELAKKYAALCDVFVMDAFGTAHRAEGSTYGVAQFAPIACAGPLLAGELEALGKAMLKPERPMVAIVGGSKVSTKLTVLESLSKIADQLVVGGGIANTFIAAAGHNVGKSLCEHDLLDTAKKLAAETNIPVTTDVVVGTEFSESTPATIKSVSDVTDGDMIFDIGPDSAKALADIIMNAKTILWNGPVGVFEFDQFSAGTKVIAEAIAASPAFSIAGGGDTLAAIDKFGIADKVSYISTGGGAFLEFVEGKVLPAVAMLEQRAKA
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDKB_MACNO
Sequence: TFIAIKPDGVQRGLCGEVMKFIQPMKQHYLDLKDMPFYAGLCKYMASGPVFAMVWEGEGIVKMMLGETNPADSKPGSIRGDFCINIGRNIIHGSDTLENAKMEIGLWFKGEEFVAYAEKAKAWVYE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.
What are the official names of this protein?
Nucleoside diphosphate kinase B, NDK B, NDP kinase B.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell projection, lamellipodium. Cell projection, ruffle.
Protein: GRPE_RHIE6
Sequence: MTDETTKNGPDATAADAAADAAAYVENDTVQEETAQPDPLELLKAENSELRDRYLRLAAEMDNLRRRTEREVKDAKSYSVAGFARDMLAVSDNLRRALDAISPEAKATADAGLTSLIEGVEMTERAMLSALERHGVRKLEPVGQKFDPNFHQAMFEVPNSEVPNNTVVQVVQAGFTIGERVLRPAMVGVAKGGPKPAEAETNSVFDEKDA
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_BUCBP
Sequence: MKRTFQPSTLKRNRSHGFRARMSTKNGRHILSRRRSKFRTRLTVSSN
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: ARMC5_RAT
Sequence: MAAARPALTDSLSFCLAQLTAAAGEGPGGGKDPATNETALGRVLLALRTRHIKAAEGIERFRARGGLRPLVALLRRTAAAGPAPSQAASGSAPPSVASAGSSPGPAPAAESPLTLSAPMRLRKTLDLALSILANCCTEGACRSEVRRIGGILPLVTILQCVRIDSIQNRTARALGNLAMEPESCGDIHSAGAVPFLVESLTACQDSQCLQSIVRALRNLADSPQHRLALAQQGAVRPLAELLATAPDPALTSALVRALLELSRGCSRACAEQLSLGGGLGPLVSLASHPKRAIREAAILILANLCAQGLVRPALGNAGGVEVLLGELRRRRGPSGSSSASQQPLVRAVCLLCREAINRARLRDAGGLELLMGLLQDPGASAWHPRVVAALVGFLYDTGALGKLQALGLVPLLARQLCGEAGEEEEEGVEAASWDFPEERTSGQPEGGSFRSLRLWLISEGYAAGPGDISPDWSPERCPMPEPSESVSPTPGQTSMSTPRTLRKLGRVPAATTEEPWGQEGPALLLLSRFSQAPDPSGALVTGPALCGLLAYVTGAPGPPNPRALRILARLTCNPACLEAFVRSYGAALLRAWLVLGVSPDDWPVPHARPVHRSQHRELGEMLLQNLTVQAESPFGVGALTHLLLSGSPEDRVACALTVPFICRKPTLWRRLLLDQGGLRLLLTALTQPAPHPLFLFFAADSLSCLQGLVSPSASPVPLPDLPLELDSPSPCLYKPLLGPAPAPAPDLHFVLDSGLQLPAQRAASAAASPFFRALLSGSFAEAQMNLVPLRGLSPSAAWPVLHHLHGCRGCGAALGPIPPPGQPLLGSKAEEALEAAGRFLLPALEEELEEAVGRIHLSPQGGPESVGEVFRLGRPRLAAHCARWTLEPGQCPRKRALALTGLVEAAGEEAGPLTEALLAVVMGVES
What is the function of this protein?
Involved in fetal development, T-cell function and adrenal gland growth homeostasis (By similarity).  Negatively regulates adrenal cells survival.  Plays a role in steroidogenesis, modulates steroidogenic enzymes expression and cortisol production (By similarity).
What are the official names of this protein?
Armadillo repeat-containing protein 5.
What are the subcellular locations of this protein?
Cytoplasm.