PharMolix/UniProtQA huggingface dataset:
Protein: COX3_GAZGA
Sequence: MTHQTHAYHMVNPSPWPLTGALSALLMTSGLIMWFHFNSTTLLMLGLTTNMLTMYQWWRDVIRESTFQGHHTPNVQKGLRYGMILFIISEVLFFTGFFWAFYHSSLAPTPELGGCWPPTGIHPLNPLEVPLLNTSVLLASGVSITWAHHSLMEGNRNHMLQALFITIALGVYFTLLQASEYYEAPFTISDGVYGSTFFVATGFHGLHVIIGSTFLIVCFFRQLKFHFTSSHHFGFEAAAWYWHFVDVVWLFLYVSIYWWGS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: BIOB_BACC4
Sequence: MKQVQTKRDWKKLAYDVVEEKMITKEDAIAILEADDTEVLEIMNAAYIIRHHHFGKKVKLNMIINTKSGLCPEDCGYCSQSIISEAPIDKYAWLTQEKIVEGAHEAIRRKAGTYCIVASGRRPTDKEVNHVIGAVKEIRETTDLKICCCLGFLNEDQAGLLAEAGVHRYNHNLNTHANNYDSICSTHTYDDRVDTVQKAKQAGISPCSGAIFGMGETIEERAEIAFELQRIDADSIPCNFLVAVKGTPLEGQKELTPVDCLKVLAMMRFVNPTKEIRISGGREINLRSVQPIGLFAANSIFVGDYLTTAGQEPTADWGMIADLGFEIEECAL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: PROB_NITEC
Sequence: MTRSILQSARRIIVKVGSSLVTNEGSGLDRQVLGGWAGQISRLKKMGKEVVLVSSGAVAEGMQRLGWKTRPAALYELQAAAAVGQMDLAQAYADCFSEYKLLTAQILLTHDDLSSRKRYLNARSTILTLLNLDIVPIINENDTVVSDEIRFGDNDNLAALVANLIEAEVLVILTDQEGLFTGDPRKHADATLISEISVSDPHIETMAGGTSSGIGRGGMQSKVMAARRAARSGAHTVIASGRVENVLVRLANGEAIGTSLLADMPVKVARKLWLADHLQVRGSVVLDDGASRALLSGGKSLLPIGVVEVRGNFERGEAISCLNTSGREIARGLANYSARESHKIMRRPSSQIEAVLGYVGEYELVHRDNLVIL
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CASPB_DANRE
Sequence: MEDITQLLSDVLEDLVESELKQFTRQLWIGVKPGVEPIPRGKLENKDRQDVVDSMVQQYSEDAGTITVQTLRKIKQNERAKRLESNLLKVQSQGQENKQNSEEPQPIPQIISQPIQQIISQPINNAGSEDLQPIQADWQRPRQIIPCSQETKNTLLKAHGDDIYTPRSGTQRKGLALLITNIQFANTQHNRNGADRDEENAEWLLRSLGFAVIKYRNLSGKDIRRAVENFSKRREHEDADSTFIVIMSHGTRIDNKDAIVGVSDDVYFIEETFSHLNSVNCPALIDKPKVILIQACRGGQSSGVLAQDSVFASDSWVHMEKDFVCFMSTMPNTFAYRNPIEGSFFISYIVDVFCSSAHRDDIMELFRKVTLRMEKDQRFQGQAKLLPCIERTSISKRFYLFPGL
What is the function of this protein?
Thiol protease which cleaves IL-1 beta (il1b), releasing the mature cytokine which is involved in a variety of inflammatory processes, and mediates apoptosis (PubMed:12464617, PubMed:30150286).  Component of the NLRP1 inflammasome, which plays a crucial role in innate immunity and inflammation (PubMed:30150286).  In response to pathogens and other damage-associated signals, recruited to the NLRP1 inflammasome in its precursor form following the recruitment of caspase caspa (PubMed:30150286).  Its subsequent activation causes the cleavage of the midformed pro-il1b and results in il1b maturation and secretion in the extracellular milieu (PubMed:30150286).  Activated by direct binding to bacterial lipopolysaccharides (LPS), which causes non-canonical inflammasome activation and results in the pyroptosis of infected cells and their extrusion into the gut lumen, as well as in cytokine secretion (PubMed:30076291).  Plays a crucial role in the restriction of bacterial infection to intestinal sites (PubMed:30076291).  Pyroptosis limits bacterial replication, while cytokine secretion promotes the recruitment and activation of immune cells and triggers mucosal inflammation (By similarity).  Promotes pyroptosis by bacterial infection by E. piscicida (PubMed:30076291).
What are the official names of this protein?
Caspase b, Caspase 19a.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14A family.
What are the subcellular locations of this protein?
Inflammasome. Cytoplasm. Note=Co-localizes with pycard, caspa and nlrp1 in the cytoplasm (PubMed:30150286). Co-localizes with pycard at large cytoplasmic aggregates, known as specks (PubMed:30150286).
Protein: TAL_PSECP
Sequence: MTTPTQQLSEAGVSIWLDDLSRGRLETGTLRKLIEEKNVVGVTTNPSIFHAAITAGTDYDATVAAQAAAGASVEETIFEITTTDVADACDLFAPVAAATKGVDGRVSIEVDPRLAWDTNGTIAEAKHLYKKVNKDNVLIKIPATIEGLEAITATLAEGISVNVTLIFSLERYRAVINAFQAGLEQAKENGHDLSKIHSVASFFVSRVDSEIDKRLDKIGTDEAKALKGKAGLANARLAYQVYEELFATERWALLAEAGALPQRPLWASTGVKDPAYPDTLYVTELVAPGVVNTMPEKTLDATFDHGVVTGDTVSGTYADANATLDALEKLGVSYNEVVALLESEGLDKFVASWKELLADVEGALASARKAS
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBN_DRANE
Sequence: METATLVAIFLSGLLVSFTGYALYTAFGQPSQQLRDPFEEHGD
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RL13_BARBK
Sequence: MVTFSQKPAEVVKKWILIDAENLVLGRLATLVANRLRGKHKPTFTPHVDDGDNVIVINADKVVLTGKKYTDKKYYWHTGYIGGIKERTARQILEGRFPERIIEKAVERMIPRGPLGRRQMRNLRVYAGSQHPHEAQQPEALDVGTLNRKNKRIA
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: CWC27_EMENI
Sequence: MSAHYATEPAPTASATLHTTFGPLHIALFAKQTPLTCRNFLQHCMDNYYAGTIFHRVVPDFIIQGGDPTGTGSGGTSIYEYPEFEYDPDARDPNEKVVLRDEIHSRLRFNRRGLVGMAKSEDGSYGSQFFITLANTERELNGQCTLFGRLEGDSLYNMLKIAEAERIEGTERPVYPVKITSCEVGDLGPFVDKVKKRQVVATGPKTEEKPAAKKKKKAKPGKALLSFGGDDEEDEDMPIRPAKPKFNPMLVTDTKLPEKESSTKGEASQTRKRPRSPSPKRQPQPSAPPKNRPKTPEPTKQLPLPNPESPERSPSPPPKQSFLSRTNAEIENLKASMRRTAHAPAAETKPKSALEAMIPQTAIRGRKRPPPGSVSASTSAPNGITGFSSNSAEAEALKMFNAFRAKLESSDSQPTAAAAKRLSVAKTDAAEERKETPDEDEESQLCDLHFIANCQSCKSWDNDVEGGANNGADDDVNDSGWLNHQLRFGKDTLGKDLNWKREHQDVDTLMVIDPREKEKELADSSRPGTKRVKGRGLERDRERERKKGRVGDLEWSKR
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.  Involved in pre-mRNA splicing (By similarity).
What are the official names of this protein?
Peptidyl-prolyl isomerase cwc27, PPIase cwc27, Rotamase cwc27.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. CWC27 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ACTP_CONCN
Sequence: MGVQFPALKTMVTVFLLLMGNMSPVVMKSSIPLRKVKMVASKVVTPGSSLYGVALKDLADTSYNITCTLQVENWIRYRLIVPSVQMVYGVVTTTPIAIEPAKREAFAVRKTSDTASGVAGSVSWELEKARRRFVIMWSVPDNFNSFGYWMGLGMTREGLVDPDKDWYGQMYSGSSDGDLTFTRKDFSYNTDSIIYSNDKFEVEGDMTNTQHAQIKIVIRPSSNNWKDLAPKIRRKLKKKPKPARQRDN
What is the function of this protein?
Pore-forming protein that forms pores of around 1 nm and causes cardiac stimulation and cytolysis.
What are the official names of this protein?
Conoporin-Cn1.
What is the protein family that this protein belongs to?
Belongs to the actinoporin family. Conoidea subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Forms an alpha-helical membrane channel in the prey.
Protein: SELO_VIBVU
Sequence: MSLWSSVKFAQRYAQLPKVFYRLVTPQPLDNNRWVIWNGELAQGFALPKHADDPQLLSVFSGAEPFSAFKPLAMKYAGHQFGVYNPDLGDGRGLLLGEMQNQQGQWFDIHLKGAGLTPFSRMGDGRAVLRSTLREYLCSEAMAALGIETTRALGMMVSDTPVYREQVEQGACLIRLAQTHIRFGHFEHFFYTEQYDELRLLADNVIEWYMPECTAHDKPYLAMFEQVVARTATMIAQWQAVGFAHGVMNTDNMSILGQTFDYGPFGFLDDYEPGYICNHSDYQGRYAFDQQPRVALWNLSALAHALSPLIERDDLELALAQYEPTLGKVFSQLMRQKLGLLSQQEGDSELFNAMFALLAENHTDYTRFFRTLSQLDREDEQTVIDLFIDRDAAHGWLSRYLERVAMEQTASGEAKSAQQRCEQMRAVNPKYILRNYLAQQAIDKAQQGDFSEVHTLAKLLKNPYDEQAEMEAYAHLPPEWGKKMVISCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: TRM5_DANRE
Sequence: MAAVWRRSARLFILLQRHHSCTFTSQNLNHFMRSQKVMTDQSQTDLGLFKPPSTVRGMTELDRSAFNQTVSVPAIRLPTNILNKAVKSLKKVALQRPGLKRVVEEHSEDGNADCGNIEHRLLLLDPNSITSSDSFGSDEAEALKAYSVPQEIQSYELKLTYENFKSEEILRAVLPEGQGVTSGFSRVGHIAHMNLREHQLPYRKLIGQVIIDKNPGITCVVNKTNTIDSTYRNFQMEVLAGESNMVAKVRENGVLYEFDFSRVYWNPRLSTEHERIVSLLHRGDTVVDVFAGVGPFAIPAARRGCAVLANDLNPESFRWLQHNAKLNKVDQKITTSNLDGRDFIRGPVRERLPALMKGSQKIHVVMNLPALALEFLDAFKGLLDPEPDQSLSNLPQVHCYGFSKENDPQRDVVERAEASLKTNLQGQCSVHLVRNVAPNKEMMCVSFTLPRGVLYKTHTQDRDTSEEPCPKKQKCEDSTN
What is the function of this protein?
Involved in mitochondrial tRNA methylation (By similarity).  Specifically methylates the N1 position of guanosine-37 in various tRNAs.  Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside.  This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.
What are the official names of this protein?
tRNA (guanine(37)-N1)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase, tRNA methyltransferase 5 homolog.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Nucleus. Cytoplasm. Note=Predominantly in the mitochondria and in the nucleus.
Protein: PACRL_HUMAN
Sequence: MQKSEGSGGTQLKNRATGNYDQRTSSSTQLKHRNAVQGSKSSLSTSSPESARKLHPRPSDKLNPKTINPFGEQSRVPSAFAAIYSKGGIPCRLVHGSVKHRLQWECPPESLSFDPLLITLAEGLRETKHPYTFVSKEGFRELLLVKGAPEKAIPLLPRLIPVLKAALVHSDDEVFERGLNALVQLSVVVGPSLNDHLKHLLTSLSKRLMDKKFKEPITSALQKLEQHGGSGSLSIIKSKIPTYCSICC
What are the official names of this protein?
PACRG-like protein.
Protein: FLGI_IDILO
Sequence: MRTLKIFALAVSLLSMLAAPVQASRIKDIASVQGVRSNQLIGYGLVVGLPGTGEQTPFTDQTFRTMLGNFGINIPANERPKIDNVAAVAVHAELPAFAKPGQKIDVTVSSVGSADGLTGGTLMQTFLKGANGEVYAVAQGSLIVGGLGAEGNDGSRIVINTPTVGRIPNGGVVEREVRSGFGSSDYLTFNLHQSDFTTAKRMAETINNLVGDGTAQAVDATSVRVRAPRDLSQRVSYMSTLENLEVQQASASAKIIVNARTGTIVVGQNVELRPAAVAHGNMQVTIAENVNVDQPNPFADGETAITPQSIIDVNQEDARMFVFQPGTTLNDLVRAVNQIGAAPGDMIAVLEALKQAGALSGELIVI
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: ATAT_LEIIN
Sequence: MRRRPAQLTATKLADEEVPELTLVPDGVSRWTGADLDALRNAARRGGAEAAQQDLERKLCRTIDILGARSQQAQEINTVLTSVARLRENSTFRLYLLTQNHRGVGILKVGVKKLFVTHPVTCGLVEVDPLCVLDFYVDESCQRQGYGKTLYSHMLKAEHVSRPEVLAIDRPSNKLLGFLRKHYGLAAYTPQVNNFVVFHSFFDHTTVSERGKLLRAPSPARALPFSSSTNATAAIGGAKAKNWAPG
What is the function of this protein?
Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules.  Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity.  Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer.  Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules.  Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released.
What are the official names of this protein?
Alpha-tubulin N-acetyltransferase, Alpha-TAT, TAT, Acetyltransferase mec-17 homolog.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase ATAT1 family.
Protein: RL22_HELP2
Sequence: MSKALLKFVRLSPTKARLIARQIQGMNAELAIASLEFTPNKAARVLSKVVASAVANGSLDAKSALIVSCRVDAGPVLRRSIPRAKGRATAIRKPTSHVFVEVVEGKEMKSSKSHKKNQAEGK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RPOA_SHEON
Sequence: MQGSVTEFLKPRLVDIEQVNSTRAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSSKEGVQEDILEILLNLKGLAVTIEGKDEAMLTLSKSGAGPVIAADITHDGDVTIVNPDHVICHLTGNNDISMRIRVERGRGYVPASARAQTEDDDRPIGRLLVDASFSPVARIAYNVEAARVEQRTDLDKLVIDMTTNGTIDPEEAIRRSATILAEQLDAFVELRDVTEPEMKEEKPEFDPILLRPVDDLELTVRSANCLKAEAIHYIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLENWPPASLADDL
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: TMOD2_MOUSE
Sequence: MALPFQKGLEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESATLPAGFRQKDQTQKAATGPFDREHLLMYLEKEALEQKDREDFVPFTGEKKGRVFIPKEKPVETRKEEKVTLDPELEEALASASDTELYDLAAVLGVHNLLNNPKFDEETTNGEGRKGPVRNVVKGEKAKPVFEEPPNPTNVEASLQQMKANDPSLQEVNLNNIKNIPIPTLKEFAKSLETNTHVKKFSLAATRSNDPVALAFAEMLKVNKTLKSLNVESNFITGTGILALVEALRENDTLTEIKIDNQRQQLGTAVEMEIAQMLEENSRILKFGYQFTKQGPRTRVAAAITKNNDLVRKKRVEGDRR
What is the function of this protein?
Blocks the elongation and depolymerization of the actin filaments at the pointed end.  The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton (By similarity).
What are the official names of this protein?
Tropomodulin-2, Neuronal tropomodulin, N-Tmod.
What is the protein family that this protein belongs to?
Belongs to the tropomodulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: HIS6_MYCPA
Sequence: MSPNSTGLAVRVIPCLDVDDGRVVKGVNFENLRDAGDPVELAAVYDAEGADELTFLDVTASSSGRATMLDVVRRTAEQVFIPLTVGGGVRTVADVDVLLRAGADKVSVNTAAIARPELLEEMARQFGSQCIVLSVDARTVPPGAVPTPSGWEVTTHGGRRGTGIDAVEWASRGADLGVGEILLNSMDADGTKAGFDLEMLQAVRSAVTVPVIASGGAGAAEHFAPAIEAGADAVLAASVFHFRELTIGQVKAAMAEAGIPVRMVR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBL_AFIC5
Sequence: MNDQSMTIRGKDRYKSGVMAYKKMGYWEPDYVPKDTDVIALFRVTPQDGVDPIEAAAAVAGESSTATWTVVWTDRLTAAEKYRAKCYRVDPVPNSPGQYFAYIAYDLDLFEPGSISNLTASIIGNVFGFKPLKGLRLEDMRLPVAYVKTFQGPATGIVVERERLDKFGRPLLGATVKPKLGLSGRNYGRVVYEALKGGLDFTKDDENINSQPFMHWRERFLYCMEAVNRAQAASGEVKGTYLNVTAATMEDMYERAEFAKELGSCIVMIDLVIGYTAIQSMAKWARKNDMILHLHRAGHSTYTRQKNHGVSFRVIAKWMRLAGVDHIHAGTVVGKLEGDPNTTRGYYDICREEFNPTKLEHGIFFDQNWASLNKMMPVASGGIHAGQMHQLLDLLGEDVVLQFGGGTIGHPMGIQAGAIANRVALEAMILARNEGRDYVAEGPEILAKAAATCTPLKSALEVWKDVTFNYESTDAPDFVPTAIAAV
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
Protein: RL21_STAAR
Sequence: MFAIIETGGKQIKVEEGQEIFVEKLDVNEGDTFTFDKVLFVGGDSVKVGAPTVEGATVTATVNKQGRGKKITVFTYKRRKNSKRKKGHRQPYTKLTIDKINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: CH60_BACCQ
Sequence: MAKDIKFSEEARRSMLRGVDTLANAVKVTLGPKGRNVVLEKKFGSPLITNDGVTIAKEIELEDAFENMGAKLVAEVASKTNDVAGDGTTTATVLAQAMIREGLKNVTAGANPMGLRKGIEKAVVAAVEELKTISKPIEGKSSIAQVAAISAADEEVGQLIAEAMERVGNDGVITLEESKGFTTELDVVEGMQFDRGYASPYMITDSDKMEAVLDNPYILITDKKISNIQEILPVLEQVVQQGKPLLIIAEDVEGEALATLVVNKLRGTFNVVAVKAPGFGDRRKAMLEDIAILTGGEVITEELGRDLKSATVESLGRAGKVVVTKENTTVVEGVGSTEQIEARIGQIRAQLEETTSEFDREKLQERLAKLAGGVAVIKVGAATETELKERKLRIEDALNSTRAAVEEGIVAGGGTSLMNVYTKVASIVAEGDEATGINIVLRALEEPVRQIAINAGLEGSVVVERLKGEKVGVGFNAATGEWVNMLETGIVDPAKVTRSALQNAASVAAMFLTTEAVVADKPEPNAPAMPDMGGMGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YGFZ_YERPB
Sequence: MAYHTPFAAQPPVASSGLPLTLISLDDWALVTLTGADRVKYLQGQVTADIDALSADQHVLCAHCDAKGKMWSNLRLFYRGEGLAFIERRSLLDNQLSELKKYAVFSKVVIEPQPDAVLIGVAGSQAKTALAEIFTELPSTEHPVTQMGNSTLLHFSLPAERFLLVTDTEQAQQLVEKLAGRAQFNDSKQWLALDIEAGFPIIDAANSAQFIPQATNIQALNGISFTKGCYTGQEMVARAKYRGANKRALYWLAGNASRVPAAGEDLEWQLGENWRRTGTVLSAIQLNDGTVWVQAVLNNDLAADSVLRVRDDALGTLAIQPLPYSLAEDK
What is the function of this protein?
Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs.  It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication.
What are the official names of this protein?
tRNA-modifying protein YgfZ.
What is the protein family that this protein belongs to?
Belongs to the tRNA-modifying YgfZ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THF1_TRIV2
Sequence: MELLRTVSDTKRTFYALHTRPINTIYRRVVEELMVEMHLLSVNVDFSYNPIYALGVVTTFDRFMQGYQPERDKESIFSAICQAVEQEPQRYRQDAERLKAVAQSLPVNDLVAWLSQANHLQQDADLQAQLQAIASNPNFKYSRLFAIGLFTLLEQSNPDLVKDEKQRTEALKTIAAGLHLSDDKLSKDLELYRSNLDKMTQALAVMADMLTADRKKREQRQQQASTPVAPPNE
What is the function of this protein?
May be involved in photosynthetic membrane biogenesis.
What are the official names of this protein?
Protein Thf1.
What is the protein family that this protein belongs to?
Belongs to the THF1 family.
Protein: GYS_NEUCR
Sequence: MAHDNREPREVKNHLLFEVATEVAHRVGGIYSVLKSKAPVTTAEYGDRYTLIGPLNHQSAAVEVEELEPSNPELKATIQAMRDRGIGILYGRWLIEGAPRVLLFDTKTAYGYMNEWKTDLWNVASIPSPDNDEETNEAIVFGYLVAWFLGEFVCHEKRKAVIAHFHEWLAGVALPLTKKRQIDVTTIFTTHATLLGRYLCAGSVDFYNNLQWFDVDAEAGKRGIYHRYCIERAAAHSCDVFTTVSHITAYESEHLLKRKPDGVLPNGLNVTKFSAMHEFQNLHQQNKEKIHDFVRGHFYGHYDFEPENTLYFFTAGRYEFRNKGVDMFIESLARLNHRLKTAGSKTTVVAFIIMPAQTTSLTVEALKGQAVIKSLRDTVDVIERGIGRRIFERSVKWHEGDPLPEEKELITSQDRVLLRRRLFAMKRHTLPPIVTHNMLNDHEDPILNQIRRVQLFNHPSDRVKIVFHPEFLSSANPVLPLDYDDFVRGTHLGVFASYYEPWGYTPAECTVMGVPSITTNLSGFGCYMEELIENSSDYGIYIVDRRSKGVDDSVNQLTQYMFEFTQKSRRQRINQRNRTERLSDLLDWKRMGMEYVKARQLALRRAYPTSFNGEEEEDFIPGVEQKISRPFSVPGSPRDRTGMMTPGDFASLQESHEGLSTEDYVAWKLPEEEDPEEYPFPLTLKQRTGPGSPLDSIQGLQLNGTR
What is the function of this protein?
Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.  Is believed to regulate the synthesis of glycogen.
What are the official names of this protein?
Glycogen [starch] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 3 family.
Protein: AROE_SYMTH
Sequence: MTKRRSTSRGPGRILGILGHPVAHSASPAMHNAAFAAQGMHAMYGAFDVPPSQLEKAIAGIRALGLLGVNVTIPHKEAVMAYLDDVAPTARQVGAVNTIVNRGGRLIGYNTDGWGFLLSLEERGVRVAGRNAVVLGAGGAARAVALHLGMAGVARLTIINRSRQRAEFLAADLARAKTPVRAEVADPGSEEARAALAEAGLVVNCTPLGMEPDTESTPLEDVGLLPAHCVVYDTVYRPLETRLLREARQHGLITVNGLAMLVHQGACAWEYWFGRRGPVDVMRTAALAALEGQP
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: HOT_CAEBR
Sequence: MSASLARGMLHKMGGSCCPHHAPTTNPFRMAKLHGNNKSTDYAFEMVCSTLRFGKGVTLEIGYDVRNLGAKKTLLITDKNVQNTIAFKNAEQALKMVNIEYEIFDDVLIEPSEKSMQKAIAFAKSKPFDSFIAVGGGSVIDTTKAAALYASNPEADFLDFVGPPFGKSLQPKNPMLPLIAVPTTAGTGSETTAAAIMDLPEHKCKTGIRLRCIKPYLAVVDPLNVMSMPRNVAIYSGFDVLCHALESYTALPYDQRSPRPARPEVRPVYQGSNPISDVWSREALRIIGQYFRRSVFDPSDEEARTEMLKASSFAGIGFGNAGVHLCHGLSYPISSQAKGCVAHDYPQDKNLIPHGLSVMTTAVADFEFTTAACPDRHLVAAQTLGADIPNNADNEYISRTLCDQLRGFMKDFGVPNGLKGMGFEYSDIDHLTEAASHSVPNIVISPKSTDRDIISKLYEKSLTVY
What is the function of this protein?
Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG).  L-3-hydroxybutyrate (L-3-OHB) is also a substrate for HOT when using 2-KG as hydrogen acceptor, resulting in the formation of D-2-HG.
What are the official names of this protein?
Hydroxyacid-oxoacid transhydrogenase, mitochondrial, HOT, 3-Hydroxypropionate-oxoacid transhydrogenase.
What is the protein family that this protein belongs to?
Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
What are the subcellular locations of this protein?
Mitochondrion.