PharMolix/UniProtQA huggingface dataset:
Protein: RPOZ_KLEP7
Sequence: MARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPEENDKTTVIALREIEEGLINNQILDVRERQEQQEQEAAELQAVTAIAEGRR
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: Y1214_METKA
Sequence: MSSLDVEEVIETIEMIRMRNLDVRAVTLGINLLDRAHPDPEELARDVREKIVEVAGDLVEVVEEVEDELGVPIVNKRIAVTPCSIVAASAVRKEGREAVLTLAEALDEAAEEVGVDYLGGYTALVYDGFTEADEAVLDTIPEAIEGTERLCASVVVADERYGINMDAVYRTAEAVKETAERTDGHGCARLVALTNAPENTPFMAGAFHGVGQPEACVNVGISGPGVVRAVVEELKDVDFRTLHDEIKRTAFKITRVGELVGRRVAERLGVEFGAVDLSLAPTPEEGDSVAEILEGIGLESCGCPGSTAALHLLMDAVKKGGAAATSRHGGYSEAFIPVSEDAGMARAAEEALTLEKLEAMTAVCSVGIDMVVVPGDTPVETIAGIIADEAAIGVVTGKPTAVRIIPAPGKEPGDEFEMGGLLGRAPVMDVSDYRPTMFRRDGRIPPKFPR
What are the official names of this protein?
UPF0210 protein MK1214.
What is the protein family that this protein belongs to?
Belongs to the UPF0210 family.
Protein: SYH_MESM1
Sequence: MMWYNLTIKQLKNVRNFMIQKPKGTSDFFLEKADLFQYILDTFRKEAELFNYSYIQTPILEFYDLFYRSVGETTDVVSKEMFIFNDRSERKMALRPEKTAGVIRSLVENKLIFNAENKFYYYGSMFRYERPQKGRYREFTQIGCEWIEDNSDFSDFEILLFASKFLGNFNFNKVILKINNLGNKVERENYLIELKKYFYKFKDKFDEISLKRLEKNPLRILDDKEINHQDFIKNAPKLFDFLNSETVQKFNNLQNYLRKSNISFEIDYSLVRGFDYYNNLVFEFVYYDEESRSELTILGGGRYSNLIEELGGPKKDAIGFAAGVERLMILLKEKEWEKPIKTSIFVFNKDHEDLYKNFDFVYKLRKRDLVVKQNVSNFKLQKIYSKIVNEGIKFLIFFDEKLNQIIIKNLINKNFLDLTNKSQEEKINLVKKFIESENKNENNSK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
Protein: KCTD4_BOVIN
Sequence: MEHKINRREKEKDYEGKHNSLEDADQGKNCKSTLMTLNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDADGHYFIDRDGLLFRHVLNFLRNGELLLPEGFRENQLLAQEAEFFQLKGLAEEVKSRWEKEQLTPRETTFLEITDNHDRSQGLRIFCNAPDFISKIKSRIVLVSKSRLDGFPEEFSISSNTIQFKYFIKSENGTRLVLKEDNTFVCTLETLKFEAIMMALKCGFRLLTSLDCSKGSIVHSDALHFIK
What are the official names of this protein?
BTB/POZ domain-containing protein KCTD4.
Protein: GLYAL_BOVIN
Sequence: MFHLQGPQLLQMLEKSLRKSLPESLKVYGTVFHMNQGNPFNLKALVDKWPDFKTVVIRPQEQEMADDFDHYTNTYQIYSKDLNNCQESLATSDVINWKQHLQIQSSQSSLNEVVQNLAATKFVKVEHTQCILYVMPETARKLLPSLPETKNLPVGYGAPKAINQEMFKLSSMDPTHAALVNKFWHFGGNERSQRFIERCIRAFPTFCLLGPEGTPASWSLMDQTGEIRMGATLPEYRGHGLISHMLAVHTRALDQLGIPVYNHTDKANKIVQKVSHNLHHIAIPHGWNQWNCEPL
What is the function of this protein?
Mitochondrial acyltransferase which transfers the acyl group to the N-terminus of glycine.  Can conjugate a multitude of substrates to form a variety of N-acylglycines.  Catalyzes the conjugation of arylacetic acids with glycine but does not have activity towards any alkyl-CoA.
What are the official names of this protein?
Glycine N-phenylacetyltransferase, ArAlk, Arylacetyl-CoA N-acyltransferase, Arylacetyltransferase, Arylacetyl-CoA:amino acid N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycine N-acyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PSAI_ATRBE
Sequence: MTNLNLPSIFVPLVGLVFPAIAMASLFLHVQKNKIV
What is the function of this protein?
May help in the organization of the PsaL subunit.
What are the official names of this protein?
Photosystem I reaction center subunit VIII, PSI-I.
What is the protein family that this protein belongs to?
Belongs to the PsaI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: NUOD_NEIMA
Sequence: MANKLRNYTINFGPQHPAAHGVLRMILELDGEQIVRADPHIGLLHRGTEKLAETKTYLQALPYMDRLDYVSMMVNEQAYCLAVEKLAGIDVPIRAQYIRVMFAEVTRILNHLMGIGSHAFDIGAMTAILYAFRDREELMDLYEAVSGARMHAAYFRPGGVYRDLPDFMPKYESSKFRNAKVLKQLNESREGTMLDFIDAFCERFPKNIDTLETLLTDNRIWKQRTVGIGVVSPERAMQKGFTGVMLRGSGVEWDVRKTQPYEVYDKMDFDIPVGVNGDCYDRYLCRMEEMRQSVRIIKQCSEWLRVNPGPVITTNHKFAPPKRTEMKTGMEDLIHHFKLFTEGMHVPEGETYTAVEHPKGEFGVYIISDGANKPYRLKIRAPGFAHLQGMDEMAKGHMLADVVAIIGTQDIVFGEVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PACC_PENEC
Sequence: EHVCERHVGRKSTHNLNLTCQWGSCNTTTVKRDHITSHLRVHVPLKPHKCDFCGKAFKRPQDLKKHVKNH
What is the function of this protein?
Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH.  At alkaline ambient pH, activates transcription of alkaline-expressed genes (including pacC itself) and represses transcription of acid-expressed genes (By similarity).
What are the official names of this protein?
pH-response transcription factor pacC/RIM101.
What is the protein family that this protein belongs to?
Belongs to the pacC/RIM101 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LPXH_VIBPA
Sequence: MTTLFISDLHLTPSRPDITECFITFMRTEAKNAEALYVLGDLFEFWVGDDDKTPFANQIRTEFKALTDQGVPVFFIQGNRDFLLGERFCKETGITLLDDVCTIDLYGTKAVILHGDTLCIDDVEYQKFRKTVHQPWLQWIFKRIPWYLKKKIVSKVQSDIRDDKQMKSLDIMDVNQSEVEKVMSQNCVNLMIHGHTHRPNTHFFDANGAKNTRIVLGDWYTQGSVLQVNSDGFELQNRPFNT
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GDS1A_XENLA
Sequence: MDNLNDALEKLKLTGTECTSDKLDGCFDCLLQALGHNNTESSEKIQQSGILQLFASILNSQSSCASKVAHIVAEIAKNELMRIPCVEAGLIPPLVQLLHSKDQEVLLQTGRALGNICYDNHEGRRAVDQEGGAQIVVDHLRSMCTLTDPSSEKLMTVFCGMLMNYSSENDSLQTQLIQMGVIPILVDLLGVHSQNTALTEMCLVAFGNLAELESSKEQFAGTNIAEEIVKLFKKQTEHEKREIIFEVLAPLAENDAIKMQLVEAGLVECLLDVVQQTVNSEKDDDIAELKTSSDLMVLLLLGDESMQKLFEGGKGSVFQRVLSWLPSNNHQLQLAGALAIANFARNDGNCIHMVDSEIVQKLLDLLDRHVEDGNVTVQHAALSALRNLAIPVVNKAKMLSAGVAEEVLKFLRSEMPPVQFKLLGTLRMLIDAQAEAAEQIGKNEKLAERLVEWCEAKDHAGVMGESNRLLSALIRHSKSKDVIRTIVQSGGIKHLVTMATSEHVIMQNEALVALGLIAALELQAAEHDLESAKLVEVLHRLLLDERSAPEIKYNSMVLICAAMGSVPLHKEVQKLAFLDVVSKLRSHENKTVAQQASLTEQKLTVQS
What is the function of this protein?
Stimulates GDP/GTP exchange reaction of a group of small GTP-binding proteins (G proteins) including Rap1a/Rap1b, RhoA, RhoB and KRas, by stimulating the dissociation of GDP from and the subsequent binding of GTP to each small G protein.
What are the official names of this protein?
Rap1 GTPase-GDP dissociation stimulator 1-A, Rap1gds1-A protein, RalB-binding protein A, XsmgGDS-A, smgGDS-A.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Endoplasmic reticulum. Mitochondrion.
Protein: MUTL_THEAQ
Sequence: MIRPLPPELRGLLARGEVLLSVKDAVRELLENALDAGARRVRVELWGGGLERIVVEDDGEGIPLEELPLAVEPFATSKLQDLERIATLGFRGQALYALRQAATLKIRSRPRGQVGGGLLLARGERVELRPAPAPPGTRVEVLGLFAGEGRDPKAEARGVLDLLKRYLLHHPHLSLVLFLEGEARLLFPGAGLKEAARQAFGGLLAERLFPLEKGGAFALEGLLTGPQVSRTRPDLLFLAVNGRPVALPEGVLRAVRRAYRELLPEGHYPVGVLNLSLPPGAYRLRLDARKEEVALSKEAEAFLEEALEEAFRGQNLARALPEPRPLPALRPPPLPACPPCATWATFRESYLLAEAEDAVYIVDQHAAHERILFEELLARLREEGLKPLPYPVLVELDEEPPEASPLFGIEGFGPGRVRLLSAPPFLHPYPLLPPEIFRESLKGEGRSRLRGLLARLACLPALKAGHPLARAEGQALLDALLACETPWVCPHGRPVLLHLKEEDLIRRFGRRSGARAKEEPHPHPPRETTREGS
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity).
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: SILC_SALTM
Sequence: MFKLKLLSISTIFILAGCVSLAPEYQRPPAPVPQQFSLSKNSLTPAVNSYQDTGWRNFFVDPQVSRLIGEALNNNRDLRMAALKVEEARAQFNVTDADRYPQLNASSGITYNGGLKGDKPTTQEYDAGLELSYELDFFGKLKNMSEADRQNYFASEEARRAVHILLVSNVSQSYFSQQLAYEQLRIARETLKNYEQSYAFVEQQLVTGSTNVLALEQARGQIESTRAEIAKREGDLAQANNALQLVLGTYRAVPSEKGIKGGEIAPVKLPPNLSSQILLQRPDIMEAEYQLKAADANIGAARAAFFPSITLTSGLSSSSTELSSLFTSGSGMWNFIPKIEIPIFNAGRNKANLKLAEIRQQQSVVNYEQKIQSAFKDVSDTLALRDSLSQQLESQQRYLDSLQITLQRARGLYASGAVSYIEVLDAERSLFATQQTILDLTYSRQVNEINLFTALGGGWVE
What is the function of this protein?
Component of the sil cation-efflux system that confers resistance to silver.  May be part of a three-component cation/proton antiporter.
What are the official names of this protein?
Probable outer membrane lipoprotein SilC.
What is the protein family that this protein belongs to?
Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: RBM47_PONAB
Sequence: MTAEDSIAAMSSSSAAGSSAKVPEGVAGAPNEAALLALMERTGYSMVQENGQRKYGGPPPGWEGPHPQRGCEVFVGKIPRDVYEDELVPVFEAVGRIYELRLMMDFDGKNRGYAFVMYCHKHEAKRAVRELNNYEIRPGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVTEGVLDVIVYASAADKMKNRGFAFVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIETTEDTIKKSFGQFNPGCVERVKKIRDYAFVHFTSREDAVHAMNNLNGTELEGSCLEVTLAKPVDKEQYSRYQKAARGGGAAEAAQQPSYVYSCDPYTLAYYGYPYNALIGPNRDYFVKAGSIRGRGRGAAGNRAPGPRGSYLGGYSAGRGIYSRYHEGKGKQQEKGYELVPNLEIPTVNPVAIKPGTVAIPAIGAQYSMFPAAPAPKMIEDGKIHTVEHMISPIAVQPDPASAAAAAAAAAAAAAAVIPTVSTPPPFQGRPITPVYTVAPNVQRIPTAGIYGASYVPFAAPATATIATLQKNAAAAAAVYGGYAGYIPQAFPAAAIQVPIPDVYQTY
What is the function of this protein?
Single-stranded RNA-binding protein that functions in a variety of RNA processes, including alternative splicing, RNA stabilization, and RNA editing.  Functions as an enzyme-substrate adapter for the cytidine deaminase APOBEC1.  With APOBEC1 forms an mRNA editing complex involved into cytidine to uridine editing of a variety of mRNA molecules.  Through the binding of their 3'UTR, also stabilizes a variety of mRNAs and regulates the expression of genes such as the interferon alpha/beta receptor and interleukin-10.  Also involved in the alternative splicing of several genes including TJP1.  Binds the pre-mRNA (U)GCAUG consensus sequences in downstream intronic regions of alternative exons, regulating their exclusion and inclusion into mRNAs (By similarity).  Independently of its RNA-binding activity, could negatively regulate MAVS by promoting its lysosomal degradation (By similarity).
What are the official names of this protein?
RNA-binding protein 47, RNA-binding motif protein 47.
What is the protein family that this protein belongs to?
Belongs to the RRM RBM47 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RRAA2_ARATH
Sequence: MAFVTTAEVCDANQELIRSGQLRALQPIFQIYGRRQIFSGPVVTVKVFEDNGLIRQFIEEKGNGRVLVVDGGGSQRCAILGGNPVVQAQNNGWAGIVVNGCIRDVDEINGCDIGVRALASHPIKASKKGLGEQRVPVNIAGTRICDGEWLYADTDGILVSQIELSV
What is the function of this protein?
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.  Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
What are the official names of this protein?
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase 2, HMG aldolase 2, Oxaloacetate decarboxylase, OAA decarboxylase, Regulator of ribonuclease activity homolog 2, RraA-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the class II aldolase/RraA-like family.
Protein: IMMX_ECOLX
Sequence: MELKKSIGDYTETEFKKIIENIINCEGDEKKQDDNLEHFISVTEHPSGSDLIYYPEGNNDGSPEAVIKEIKEWRAANGKSGFKQG
What are the official names of this protein?
Colicin-E8 immunity protein in ColE6, E8Imm[E6].
What is the protein family that this protein belongs to?
Belongs to the colicins ColE2/ColE8/ColE9 and pyocins S1/S2 family.
Protein: ACYP2_RABIT
Sequence: MSTAGPLKSVDYEVFGRVQGVCFRMYTEGEAKKIGVVGWVKNTSKGTVTGQVQGPEDKVNSMKSWLSKVGSPSSRIDRTNFSNEKTISKLEYSNFSIRY
What is the function of this protein?
Its physiological role is not yet clear.
What are the official names of this protein?
Acylphosphatase-2, Acylphosphatase, muscle type isozyme, Acylphosphate phosphohydrolase 2.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: FLIW_SYMTH
Sequence: MDNVFEFPAGLYGFPDLKRFVVVDVPGAGDVVKQLVSTEDPNVGFTLVFPFAFFPRYSPDIPEEELVAVGAESAEQVLLYAIASVPEDFRKATANLRAPVLFNPFTRKGRQVILGDDRYGIREPLFQGADRIPAEEGR
What is the function of this protein?
Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin.  Binds to flagellin and participates in the assembly of the flagellum.
What are the official names of this protein?
Flagellar assembly factor FliW.
What is the protein family that this protein belongs to?
Belongs to the FliW family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_MYCSM
Sequence: MTLKVDVKTPAGKTDGSVELPAELFDVEPNIALMHQVVTAQLAAKRQGTHSTKTRGEVSGGGKKPYRQKGSGRARQGSTRAPQFTGGGTVHGPKPRDYSQRTPKKMIAAALRGALSDRARNDRIHAVTELVEGQTPSTKSAKTFLGTLTENKKVLVVIGRTDEVGAKSVRNLPGVHVISPDQLNTYDVLNADDVVFSVEALNAYISANSKEGASV
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: Z394_ENCCU
Sequence: MKMNDSSKLKKLYQIEEKKFAERVRRYEDIGHMMDTHQFYLEDVVLKKEEMLYKYISPSQGIAELSEEDSLGFDYEFIHKSVGNKEWRGGISTGEMIKVRKLPCTNLAHGGERNARTSSRMQKTKGGRVYACEIEGCNKKYTSSFGLKYHMKEGHSEEKMNIFKPYVCPFSGCDKKYKNNNGLKYHIKHYHDGQTA
What are the official names of this protein?
Zinc finger C2H2 protein ECU03_0940.
Protein: ATPA_BACC4
Sequence: MSIRAEEISALIKQQIENYQSEIEVSDVGTVIQVGDGIARAHGLDNVMAGELVEFSNGVMGLAQNLEENNVGIIILGPYTEIREGDEVRRTGRIMQVPVGKELIGRVVNPLGQPVDGLGPINTTNTRPIESPAPGVMDRKSVHEPLQTGIKAIDALVPIGRGQRELIIGDRQTGKTAVALDTIINQKDEDMICIYVAIGQKESTVRNVVETLRKHGALDYTIVVTASASQPAPLLYLAPYAGVTMGEEFMYNGKHVLVVYDDLSKQAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDAKGGGSLTALPFIETQAGDVSAYIPTNVISITDGQIFLQSDLFFSGVRPAIDAGTSVSRVGGSAQIKAMSKVSGTLRLDLASYRELEAFAQFGSDLDKATQAKLNRGARTVEVLKQGLHKPLRVEKQVIILYALTRGFLDDIPVVDITRFEEEFHAWLDSNATDLLEEIRTTKKLADDDKFAAAINGFKKVFVASE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ATPL_SHIDS
Sequence: MENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPDLIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LDHD_STRP1
Sequence: MKLKLYNVRGEEAVLAKKWADDNGIEISLTESPLTPETVKEAEGFDGIANAQIGPLDDAIYPLLKEMGIKQIAQHSASVDMYNLDLATENDIIITNVPSYSPESIAEFTVTIVLNLIRHVELIRENVKKQNFTWGLPIRGRVLGDMTVAIIGTGRIGLATAKIFKGFGCKVVGYDIYQSDAAKAVLDYKESVEEAIKDADLVSLHMPPTAENTHLFNSDLFKSFKKGAILMNMARGAVIETQDLLDALDAGLLSGAGIDTYEFEGPYIPKNFEGQEITDSLFKALINHPKVIYTPHAAYYTDEAVKNLVEGALNATVEIIKTGTTTTRVN
What are the official names of this protein?
D-lactate dehydrogenase, D-LDH, D-specific 2-hydroxyacid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
Protein: NDK_BURPS
Sequence: MALERTLSIIKPDAVAKNVIGQIYSRFENAGLKIVAARMAHLSRADAEKFYAVHAERPFFKDLVDFMISGPVMIQVLEGEDAILKNRDLMGATDPKKAEKGTIRADFADSIDANAVHGSDAPETARAEVAFFFPEMNVYSR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPD_SALTS
Sequence: MLPDKGWLVEARRVPSPHYDCRPDDEKPSLLVVHNISLPPGEFGGPWIDALFTGTIDPDAHPFFAEIAHLRVSAHCLIRRDGEIVQYVPFDKRAWHAGVSNYQGRERCNDFSIGIELEGTDTLAYTDAQYQQLAAVTRTLIASYPAIADNMTGHCNIAPDRKTDPGPAFDWPRFRALVALSSHKEMT
What is the function of this protein?
Involved in cell wall peptidoglycan recycling.  Specifically cleaves the amide bond between the lactyl group of N-acetylmuramic acid and the alpha-amino group of the L-alanine in degradation products containing an anhydro N-acetylmuramyl moiety.
What are the official names of this protein?
1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD, N-acetylmuramoyl-L-alanine amidase.
What is the protein family that this protein belongs to?
Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_RICCK
Sequence: MTNILSPEKSENDQELPIRPSYLQEFVGQQQIKENLLVFIKAAKSRNEHLDHTLFYGPPGLGKTTLAKIVSNEIGVNFKSTSGPAILKAADLAAILTNLEKNDVLFIDEIHRLNTSVEEVLYPAMEDFELDIIIGEGPAARSVKINLPHFTLIGATTRLGLLSNPLRDRFGIPMRLNFYNNDELKKVLNRASKLLDIDLTESGSEEIAKRSRGTPRIALRLLRRIRDFAVVDSKSVVDKEIADFGLNRLEVDHIGLDSNDYRYLKFIAANYNGGPVGIETIAAALSEQRDALEETIEPYLIQIGLLQRTPRGRVITIAAFEHLKMPVPNKSHNQFNIFNDNE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: PANB_IDILO
Sequence: MATTKTSIATLQKMKREGTKISSLTAYDSSFAKLMTEQGVDFILVGDSLGNVVQGRDSTVPVTVDDMIYHTQCVRRGASNAFVIADMPFMTYSTPEQAYDVAAALMQAGANMVKLEGGHWLVETIEGLKTRGIPVCAHLGLLPQSVNVLGGYKVQGKEQQQADDTLNQALALEQAGAQLLVLECVPASLGKRITEQLSIPTIGIGAGADTDGQILVMHDMLGMNSDYLPKFAKDFLAQGGSLADAFRLYSEQVRSGEFPTAEHSYK
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EAF1A_ARATH
Sequence: MHGSVSGYLLVNAEVDSMGGVIDSGGGIGVKTSPRRTAIEKAQAELRQEYDVREERRRELEFLEKGGNPLDFKFGIATSHSVQSTSLTDQQAEHFVNSEVKDSFALTASPHGDSVESSGRPGVPTISEPNTADNLLLFDSENKSVEGERNLRHPNRQNRTSESERSSKAHTNQNTKETEDSAIFRPYARRNRSKISRDPARSSSTDLVQNRGGLATSISIRRGSVEGKGCIPEAANQKDMHTTSVSCPVFANSNGNIVPKNRVSSNSLNTKVDGEPVVRESTAGSKTSLLKDEADISYSKSSAYLPVGESGLAGEKAQLVSTGGSPKAATIAGQKNSSTQLNGLRDSTVEEESLTNRGATGTNGLESESSHANNVEVNVDNERDLYKVDKLDSDEISMQKTLRVEGLLDQTVGEMTKTKIEDETGQSTTIISECIPECEMQMKSVKIENQSHRSTAEMQTKEKSSETEKRLQDGLVVLENDSKVGSILSENPSSTLCSGIPQASVDTSSCTVGNSLLSGTDIEALKHQPSSDAVMLDTVKEDAILEEARIIQAKKKRIAELSCGTAPVEVREKSQWDFVLEEMAWLANDFAQERLWKMTAAAQICHRVALTCQLRFEERNQHRKLKKIASVLSNAILQFWSSVEAEVPGELEETSLGIVKETCQESNCLNGRRCLAAGVKEYASRFLKYNNSSISYHSAAPSTPDNMCDPEILDISMVDQLTEASLFYSVPSGAMEVYLKSIESHLTRCEKSGSSMQEEVDTSAYDTAGDIGYNVTAFDEDEGETSTYYLPGAFESSRSFNISHKKRKNLMKSHSARSYDLGDDLPYVNNTGGSNSSSLMAKRPDSNINAGSVPTRRVRTASRQRVVSPFGCATTGNLPVPSKTDASSGDTSSFQDEYSSLHGGSAVQKGTEVESSVNFEKLLPYDMAETSGRPKKKKKTHQGSAYDQTWHLDPSVHVEQKDHWKKRPENNFDMNGLYGPHSAKKQKTTKQLVENNFDMAIPHTGSIPSPAASQMSNMSNPNKSIKFIGGRDRGRKIKGLKISPGQHGSGNPWSLFEDQALVVLVHDMGPNWELISDAMNSTLKIKCIYRNPTECKDRHKILMDKTAGDGADSAEDSGNSQSYPSTLPGIPKGSARQLFQRLQGPMEEDTLKSHFEKICLIGKKLHYRKTQSVIGVSVVSFVHGIQFSSCTGAGISQSLDIPGLHVSKYSCKSWLGFPENDGRDSKQIVPVHNSQVMALSQVFPNNLNGGVLTPLDVCDASTSGQDVFSLENPGLPMLNQGTPVLPTSGAHPSTPGSSGVVLSNNLPTTSGLQSASVRDGRFNVPRGSLPLDEQHRLQQFNQTLSGRNLQQPSLSTPAAVSGSDRGHRMVPGGNAMGVSGMNRNTPMSRPGFQGMASSAMPNTGSMLSSGMVEIPNTGNIHSGGGASQGNSMIRPREAVQHMMRMQAAQGNSPGIPAFSNLSSGFTNQTTPVQAYPGHLSQQHQMSPQSHVLGNSHHPHLQSPSQATGAQQEAFAIRQRQIHQRYLQQQQQQQQFPASGSMMPHVQQPQGSSVSSSPQNSPQTQPPVSPQPLSMPPVSPSPNINAMAQQKPQKSQLALHGLGRSPQSGTSGVNNQAGKQRQRQLQQSARQHPHQRQPTQGQQLNKQLKGMGRGNMIHQNITVDQSHLNGLTMPQGNQATEKGEIAVPVRPDQQSSVGTTTSTNLQSKPFVSPLSSNHSQQLPKSFPGALPPSPQQQMQLHSDNSIQGQSSPATPCNILSTSSPSIAPAVAPSNHQHLLIHQKQRNQVQSTAQRVVQHNHLGNSELSKKSQAERMPRVPQSVTNTTQTVSMGTTKGMPQASNDLKNIKAVGSTAVPALEPPSCVASVQITASKVVNSSNTDSAGNDPVSTPNQGLAQKHGIKGVTQRQQQSLPSEEKRPKLPEKPTVQNQKHLASEEQPHLEEAQELSSSKPPDTKVE
What is the function of this protein?
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A.
What are the official names of this protein?
Chromatin modification-related protein EAF1 A, ESA1-associated factor 1 A.
What is the protein family that this protein belongs to?
Belongs to the EAF1 family.
What are the subcellular locations of this protein?
Nucleus.