PharMolix/UniProtQA huggingface dataset:
Protein: ALKB5_BOVIN
Sequence: MAAASGYTDLREKLKSMTSRDNYKAGSREAAAAAAAAVAAAAAAAAAAEPYAAPGVKRKYPEDSDPERSDFEEQQLQKEEEARKVKSGIRQMRLFSQDECAKIEARIDEVVSRAEKGLYNEHTVDRAPLRNKYFFGEGYTYGAQLQKRGPGQERLYPPGDVDEIPEWVHQLVIQKLVEHRVIPEGFVNSAVINDYQPGGCIVSHVDPIHIFERPIVSVSFFSDSALCFGCKFQFKPIRVSEPVLSLPVRRGSVTVLSGYAADEITHCIRPQDIKERRAVIILRKTRLDAPRLETKSLSSSVLPPSYASDRLSGNNRDPALKPKRSHRKADPDAAHRPRILEMDKEENRRSVLLPAHRRAGRFSSENYRRKSYEPGEDCSEAAGSPARKVKMRRH
What is the function of this protein?
Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6)-methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes (By similarity).  Can also demethylate N(6)-methyladenosine in single-stranded DNA (in vitro).  Requires molecular oxygen, alpha-ketoglutarate and iron.  Demethylation of m6A mRNA affects mRNA processing and export (By similarity).  Required for the late meiotic and haploid phases of spermatogenesis by mediating m6A demethylation in spermatocytes and round spermatids: m6A demethylation of target transcripts is required for correct splicing and the production of longer 3'-UTR mRNAs in male germ cells (By similarity).
What are the official names of this protein?
RNA demethylase ALKBH5, Alkylated DNA repair protein alkB homolog 5, Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5.
What is the protein family that this protein belongs to?
Belongs to the alkB family.
What are the subcellular locations of this protein?
Nucleus speckle.
Protein: BCPSF_ORIVU
Sequence: MEFPASVASLSANTVGSNDVLRRSVAYHPNIWGDFFLAHTSEFMEISIAEKEEHEWLKEEIKKLLVQTEYDSILKLELIDSIQRLGVSYHFEKEIDRILRYVHQTYPIYETENKDLRMLALRFRLLRQHGFHVPCDVFSEFIDAEGNLMESIAYDIQGILSLYEASNYGVLGEEILDKALDSCSSHLESLITDTNDDRLSRQVKEALKIPISKTLTRLGARKFISMYKEDDSHNEKLLKFAMLDFNMVQRLHQNELSHLTSWWKELDFANKLPFARDRLVECYFWIMGVYFEPRHEIARKILTKVIYMASVLDDTYDVYGTLDELILFTSVVRRWDISGIDELPTYMRIYLRALFDVYVEMEEEMGKIGKSYAVEYAKEEMKRLAEVYFQEAQWFFSKYKPTMQEYMKVALLSSGYMMMTINSLAVIEDPITKKEFDWVVSEPPILKSSSIITRLMDDLAGYGSEDKYSAVHLYMNEKGVSEEEAFQELRKQVKNSWKNRNKECLEPRSASVPILTTVVNFTRVVVVLYTDEDAYGNSKNKTKDMIKSILVDPV
What is the function of this protein?
Involved in the biosynthesis of phenolic sesquiterpenes natural products (Ref. 2).  Sesquiterpene synthase converting (2E,6E)-farnesyl diphosphate (FPP) to (E)-beta-caryophyllene and alpha-humulene (PubMed:20419468, Ref. 2).
What are the official names of this protein?
(E)-beta-caryophyllene synthase, Alpha-humulene synthase, Terpene synthase 6, OvTPS6.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: RS12_SHEON
Sequence: MATVNQLVRKPRAPKVDKTNVPALNACPQKRGVCTRVYTTTPKKPNSALRKVARVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGALDCAGVTSRRQSRSKYGAKRPKS
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: TRUA_THEVB
Sequence: MMTAIAPSQSGQRLALLIQYQGTHFHGWQRQVGQRTVQEVIEQAIASVVNHPVSVVAAGRTDTGVHAAGQVAHVTVNSPIPVHRWPGILNARLPADVVIRAAAAVPPDWHARFSALWRRYRYTLYTDPCPNIFLRPWTWHYYYAPLDVAKMAAVLQPLVGRHHLSAFHRSGSNRAHSWVEVQAVSCQRRGALVEIEVQASGFLYGMMRLLVGLLVQVGQGQRSPASFTEIWQQEQRHLVKYAAPPSGLCLLGVGYPESPFPLALCTEAMPQFQLASVCPELSIA
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: PLSX_LEUCK
Sequence: MKIAVDAMGGDFAPLEIVKGIEIARDRYDDIDFQLYGTASEVKPLVTNWERIELIPTTEVIEMGDEPVKAMRRKKDSSMVRAALAVKEGHADALFSAGNTGALLSSAIFLVGRIKGVDRPALATALPSFEGEHDQFVFMDLGANADSKPAHLYQYGILGSFYASHVLGIQSPTVRLLNNGAEEDKGDEVHKVAHQLMKNAPSFNFLGNIEARELLEGTADVVVADGFSGNAALKATEGTALMMLKQIKAAIMDSGTRGKMGGALLKPAFKSIQKKLDYNEAGGAVILGVKAPVVKTHGSAKATAVANTMGQIKTMIDQHLVSDIQNYIDTHTEELQAGKEALNAQINA
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: PTR30_ARATH
Sequence: MEAAKVYTQDGTVDLQGRPVLASKTGRWRACSFLLGYEAFERMAFYGIASNLVNYLTKRLHEDTISSVRNVNNWSGAVWITPIAGAYIADSYIGRFWTFTASSLIYVLGMILLTMAVTVKSLRPTCENGVCNKASSLQVTFFYISLYTIAIGAGGTKPNISTFGADQFDSYSIEEKKQKVSFFNWWMFSSFLGALFATLGLVYIQENLGWGLGYGIPTVGLLVSLVVFYIGTPFYRHKVIKTDNLAKDLVQVPIAAFKNRKLQCPDDHLELYELDSHYYKSNGKHQVHHTPVFRFLDKAAIKTSSRVPCTVTKVEVAKRVLGLIFIWLVTLIPSTLWAQVNTLFVKQGTTLDRKIGSNFQIPAASLGSFVTLSMLLSVPMYDQSFVPFMRKKTGNPRGITLLQRLGVGFAIQIVAIAIASAVEVKRMRVIKEFHITSPTQVVPMSIFWLLPQYSLLGIGDVFNAIGLLEFFYDQSPEEMQSLGTTFFTSGIGLGNFLNSFLVTMIDKITSKGGGKSWIGNNLNDSRLDYYYGFLVVISIVNMGLFVWAASKYVYKSDDDTKEFSGGGCVQMEAKALDTSPLSI
What are the official names of this protein?
Protein NRT1/ PTR FAMILY 5.1, AtNPF5.1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TSAD_DEHMC
Sequence: MKILGIESSCDETAASVVEDGVNILSNRISSQIDIHSRYGGVVPEVASRQHLLSILPVIKDALEEARTGLDEISAIAITNGPGLAGSLIVGVNAAKAIAAARRIPLVAVNHLHGHIYANWLFGKIPEFPCLCLTVSGGHTDLVLMSGHGQYQLLGRTRDDAAGEAFDKAARILGLSYPGGPAIDRASQDGQAVLDLPRSWIPGSHDFSFSGLKTALLRLVESGEVCSVNDAAASFQKAVVDVLVTKTINCAQEYNVKQILLAGGVAANNLLRKQLSEKSSLPVSIPPMGLCTDNAAVIASCGYFRFISGKQDGLDMDVLPALSVTS
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_BURA4
Sequence: MVVAVYPGTFDPLTRGHEDLVRRASSIFDTLVVGVADSRAKKPFFSLEERLKIANEVLGHYPNVKVMGFKGLLKDFVRTNNARVIVRGLRAVSDFEYEFQMAGMNRYLLPDVETMFMTPSDQYQFISGTIVREIAQLGGDVSKFVFPSVEKWLTEKVAAMGGPAA
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1097_CITK8
Sequence: MAGHSKWANTRHRKAAQDAKRGKIFTKIIRELVTAAKLGGGDPDANPRLRAAVDKALSNNMTRDTLNRAIARGVGGDDDANMETIIYEGYGPGGTAVMVECLSDNRNRTVAEVRHAFSKCGGNLGTDGSVAYLFSKKGVISFEQGDEDTIMEAALEAGAEDVVTFDDGAIDVYTAWEEMGKVRDALEAAGLKADNAEVSMIPSTKADMDAETAPKLMRLIDMLEDCDDVQEVYHNGEISDEVAATL
What are the official names of this protein?
Probable transcriptional regulatory protein CKO_01097.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAL_META3
Sequence: MKFFLDTANVDKIKEFNDLGMVDGVTTNPTLIAKEGRDFHEVIKEICSIVDGPVSAEVIALDAEGMIEEARELVKLADNVVVKIPMTKEGLKAVNVLSKEGIQTNVTLIFSANQALMAAKAGATYVSPFVGRLDDNGQNGMDLIAEIVQIFTNYGIATEVIVASVRHPIHVIQSAEMGADVATIPFAVLDKMFNHPLTDKGIESFMKDWEEFQKNK
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URK_SHEHH
Sequence: MNSKDCVVIGIAGASASGKSLIAKTIYEELCRDLGTDQIGVIAEDAYYRDQGHLSMDQRVLTNYDHPKALDHELLCTHLRALKQGHAVDIPVYSYNDHTRTDEKVTLTPKKVIILEGILLLTDPALRKEMDASVFMDTPLDICFMRRLSRDVAERGRTMESVMQQYTETVRPMFLQFIEPSKQYADIIVPRGGKNRIATDILKARIQHLLAK
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YHBQ_SHIDS
Sequence: MTPWFLYLIRTADNKLYTGITTDVERRYQQHQSGKGAKALRGKGELTLAFSAPVGDRSLALRAEYRVKQLTKRQKERLVAEGTGFAELLSSLQTPKIKSD
What are the official names of this protein?
UPF0213 protein YhbQ.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: CODY_ANOFW
Sequence: MNLLEKTRKINAMLQNAAGKPVNFKEMAETLCEVIEANVFVLSRRGKLLGFAIKQTIENERMKKMLADRQFPEEYTKNLFNITETSPNLDINSEYTAFPVENKDLFKNGLTTIVPIIGGGERLGTLILSRLDKEFHDDDLILAEYGATVVGMEILREKAEEIEEEARSKAVVQMAISSLSYSELEAIEHIFEELDGTEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGTYIKVLNDKFLTELEKLKHH
What is the function of this protein?
DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability.  During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.
What are the official names of this protein?
Global transcriptional regulator CodY.
What is the protein family that this protein belongs to?
Belongs to the CodY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: USTL_USTVR
Sequence: MTSLTGLALLLCVLASQSWAARVQKTLRIAWEKGAPNGQSREMIFTNGVFPGPELIFDEDDDVEITVHNDMNRNTTVHWHGIAQEGTPWADGVIGLSQQPIRPGESFVYRFKASPPGTHWYHSHERMTLVDGLHGAFFIRPKRDMKDLWSKISNDPKDIDAMSKAALDPKLMVLSDWSRFTSEEYWKAIEDSKLLLFCVDSILLNGHGEVYCPPQEFLVNQTQWGPQHFTFPDQNVTDKGCFPAVEEGIQGPWVNQSLPEKIPAHIQSGCVPSAGSNYTVEVDPADGWVSMNFIAAASNKQVDFSIDEHPMWIYEVDGNYVQPHKFVAAAITAGERFSVMVKLDKQPGRYTIRLPDSGATQVISGFANMVYKGAEHVSPPTKPYVTYGGLSGRPETDTESYAPYNISADYMPPWPANPPAATADEEYLLVMGRAGSSFQYTMNTNYLYPMDFKADRPLLHYPNQTVGTEDEKLVIRTKNGSWVDLILQVAVLPGDGAAFEHMMHKHGSKTWRIGNGAGVWKYKSVAEAIAAEPESFNLKDPGLRDSWLTMFSPVPAGGYWSVFRYQVTNPGPWLFHCHFELHAMGGMSIALLDGVDVWPQVPEEYAVRHHPSQGTQTLAATPNASKPWYNGMLNFMQAVLGILPGQGSEELRR
What is the function of this protein?
Laccase; part of the gene cluster that mediates the biosynthesis of ustilaginoidins, dimeric gamma-naphthopyrones isolated from different fungal species (PubMed:31050129).  The first step in the biosynthesis of ustilaginoidins is the production of gamma-naphthopyrone precursor YWA1 by the non-reducing polyketide synthase ustP, via condensation of one acetyl-CoA starter unit with 6 malonyl-CoA units (PubMed:31050129).  YWA1 is then probably substrate of the ustZ to yield norrubrofusarin via a dehydration reaction (Probable).  A key enzyme in the biosynthetic pathway is the laccase ustL, which catalyzes the oxidative dimerization of norrubrofusarin to ustilaginoidin A (PubMed:31050129).  It can produce the M- and P-atropisomers in varying amounts, depending on the reaction conditions (PubMed:31050129).  For the biosynthesis of 3-methylustilaginoid in derivatives such as chaetochromin A, a methylated derivative of YWA1 is required (Probable).  The C-methylation is considered to be catalyzed by ustM, the phosphopantetheine attachment site of which indicates that it acts on the growing polyketide chain before release of the product (Probable).  For the biosynthesis of chaetochromin A, it is assumed that saturation of the D2 double bond takes place before dimerization, and is probably catalyzed by an external reductase because no candidate gene was identified within the cluster (Probable).
What are the official names of this protein?
Laccase ustL, Ustilaginoidins biosynthesis cluster protein L.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
Protein: DNAJ_STRP3
Sequence: MNNTEYYDRLGVSKDASQDDIKKAYRKMSKKYHPDINKEAGAEQKYKDVQEAYETLSDSQKRAAYDQYGAAGAQGGFGGGAGGFGGFDGGGFGGFEDIFSSFFGGGGSRNPNAPRQGDDLQYRVNLSFEEAVFGVEKEVSYNREATCGTCLGSGAKPGTAPVTCRKCHGSGVMTIDTQTPLGMMRRQVTCDICHGSGKEIKEPCQTCHGTGHEKQAHKVSVKIPAGVETGQQIRLQGQGEAGFNGGPYGDLFVILNVLPSKQFERNGSTIYYNLDISFTQAALGDTVEIPTVHGDVEMAIPAGTQTGKTFRLKGKGAPKLRGGGQGDQHVTVNIVTPTKLNDAQREALQAFAEASGEKMLHPKKKGFFDKVKDALEDI
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_PSYCK
Sequence: MKVLGLETSCDETGLAIFDSEQVTSDNKGLLGQVLYSQIELHALYGGVVPELASRDHIRKLVPLFNELLQQCNITKDEIDAVAYTKGPGLIGALMTGALFGRSLAYGLDIPAIGVHHMEGHLLAPLMGANPPAFPFVSLLVSGGHTLLIAAHGIGQYEILGESIDDAAGECFDKAAKMLGLPYPGGPNIAKLAESGNSDAYSLPRPMLHRGLDFSFSGMKTAVHNLIKDTPCSGGSGNGSDSDPQVRADIAASFQHAVVDTLVKKCVKALKQVNMSRLVIAGGVSANSHLRKTLERELAKINATVHYAPPALCTDNGAMIAYAGYERLQAGQADDLAVSCVPRWPMTELPAV
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y162_HELPY
Sequence: MGRAFEYRRAAKEKRWDKMSKVFPKLAKAITLAAKDGGSEPDTNAKLRTAILNAKAQNMPKDNIDAAIKRASSKEGNLSEITYEGKANFGVLIIMECMTDNPTRTIANLKSYFNKTQGASIVPNGSLEFMFNRKSVFECLKNEVENLKLSLEDLEFALIDYGLEELEEVEDKIIIRGDYNSFKLLNEGFESLKLPILKASLQRIATTPIELNDEQMELTEKLLDRIEDDDDVVALYTNIE
What are the official names of this protein?
Probable transcriptional regulatory protein HP_0162.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEND_MYCTA
Sequence: MNPSTTQARVVVDELIRGGVRDVVLCPGSRNAPLAFALQDADRSGRIRLHVRIDERTAGYLAIGLAIGAGAPVCVAMTSGTAVANLGPAVVEANYARVPLIVLSANRPYELLGTGANQTMEQLGYFGTQVRASISLGLAEDAPERTSALNATWRSATCRVLAAATGARTANAGPVHFDIPLREPLVPDPEPLGAVTPPGRPAGKPWTYTPPVTFDQPLDIDLSVDTVVISGHGAGVHPNLAALPTVAEPTAPRSGDNPLHPLALPLLRPQQVIMLGRPTLHRPVSVLLADAEVPVFALTTGPRWPDVSGNSQATGTRAVTTGAPRPAWLDRCAAMNRHAIAAVREQLAAHPLTTGLHVAAAVSHALRPGDQLVLGASNPVRDVALAGLDTRGIRVRSNRGVAGIDGTVSTAIGAALAYEGAHERTGSPDSPPRTIALIGDLTFVHDSSGLLIGPTEPIPRSLTIVVSNDNGGGIFELLEQGDPRFSDVSSRIFGTPHDVDVGALCRAYHVESRQIEVDELGPTLDQPGAGMRVLEVKADRSSLRQLHAAIKAAL
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: C1QRF_MOUSE
Sequence: MLLVLVVLIPVLVSSGGPDGHYEMLGTCRMVCDPYPARGPGAGARSDGGDALSEQSGAPPPSTLVQGPQGKPGRTGKPGPPGPPGDRGPPGPVGPPGEKGEPGKPGPPGLPGSGGSGAISTATYTTVPRVAFYAGLKNPHEGYEVLKFDDVVTNLGNNYDAASGKFTCNIPGTYFFTYHVLMRGGDGTSMWADLCKNGQVRASAIAQDADQNYDYASNSVILHLDAGDEVFIKLDGGKAHGGNSNKYSTFSGFIIYSD
What is the function of this protein?
May regulate the number of excitatory synapses that are formed on hippocampus neurons.  Has no effect on inhibitory synapses.
What are the official names of this protein?
C1q-related factor, C1q and tumor necrosis factor-related protein 14, C1q/TNF-related protein 14, CTRP14, Complement component 1 Q subcomponent-like 1.
What are the subcellular locations of this protein?
Secreted.
Protein: TSAC_SHEB5
Sequence: MLQLHPSDIKDIILQGGVIAYPTEAVYGLGCDPDNDTAIQKLLAVKQRPWQKGLILVASDFQQLLAYVDESQLTAEQLEFAFSKWPGPFTFVMPIKAHVSKYLCGEFDSIAVRVSAHAGVQALCRALNKPLVSTSANLAGEDPALTAAEILADFTGKIDALVLGELGEQRQPSTIIDARSGKILRNGQ
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALP_HYPAT
Sequence: MTSIRRLALYLGALLPAVLAAPAALHKKPEAVPNKFIVTLKEGASIDTDSHLAWVTDIHTRSLTKRSTAGVEKTYNIHTWNAYAGEFDEETIEQIKSNPDVASVEPDYIMHLSDIVEDKRALTTQSGAPWGLGTVSHRTSGSTSYIYDSSAGAGTFAYVVDSGINTSHQQFGGRASLGYNAAGGQHVDTLGHGTHVSGTIGGSTYGVAKQASLISVKVFAGESASTSVILDGYNWAVNDIVSKSRASKSAINMSLGGPASSTWTTAINAAFNQGVLTIVAAGNGDSLGNPQPVSGTSPANVPNAITVAALDINWRTASFTNYGAGVDVFAPGVNILSSWIGSNTATNTISGTSMATPHVVGLALYLQSLEGLTSPTAVTNRIKALATSGRVTGSLNGSPNVIIFNGNSS
What is the function of this protein?
Serine protease, secreted specifically during the mycoparasitic process, which is involved in the degradation of phytopathogen cell walls, membranes and of the proteins released after lysis of the host.
What are the official names of this protein?
Alkaline proteinase, ALP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: VPS53_YEAST
Sequence: MLEGTVDYDPLEDITNILFSKESLNNIDELISITRSYKKQLQEDILKEENELKEHPKNSAEIEASLRKVFQDFKETQDVSASTELTISNLTEGISYLDIAKKNLTHSLTLFQNLKILTDSYIQCNELLSQGSFKKMVSPYKIMCSLAENTFISYKSLDEINYLLSSISRLKGDTLSKIKQNYNALFSGGNISEHDTALTMELREGACELLDCDTSTRAQMIDWCLDKLLFEMKEIFRVDDEAGSLENLSRRYIYFKKILNNFNSKFADYFLKDWEMAVRLTTTFYHITHKDLQTLLKREFKDKNPSIDLFMTALQSTLDFEKYIDVRFSKKIKEPKLSSCFEPYLTLWVSHQNQMMEKKFLSYMSEPKYPSNETESLVLPSSADLFRTYRSVLTQTLELIDNNANDSILTSLANFFSRWLQTYSQKILLPLLLPDNIEVQDKLEAAKYTVLLINTADYCATTIDQLEDKLSEFSGNREKLANSFTKTKNIYDDLLAKGTSFLLNRVIPLDLNFVWREFINNDWSNAAIEDYSRYMVTLKSVLKMPALTDASIKQQQEQPSTLAFILSQFNRDVYKWNFLDKVIDIITTNFVSNTIRLLQPVPPFSLAGSKRKFETRTVVNIGEQLLLDLELLKEIFHTLPESVSNDSDLRENTSYKRVKRHADNNIDQLLKFIKLLMAPLDSADDYYETYSKLTNNNPDSAVWSFVLALKGIPWDLALWKKLWSAYNLETDDTDEGSRPDSNRDLFIFKWDKVLLGQFENNLARMQDPNWSKFVRQDLKISPPVMKRIVSTPQIQQQKEEQKKQSLSVKDFVSHSRFFNRGT
What is the function of this protein?
Involved in retrograde transport from early and late endosomes to late Golgi by linking the vesicle through the t-SNARE TGL1 to the Golgi, leading to the membrane fusion between late Golgi and endosomal vesicles.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 53.
What is the protein family that this protein belongs to?
Belongs to the VPS53 family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein.
Protein: FADB_SHIDS
Sequence: MLYKGDTLYLDWLEDGIAELVFDAPSSVNKLDTATVASLGEAIGVLEQQSDLKGLLLRSNKAAFIVGADITEFLSLFLVPEEQLSQWLHFANSVFNRLEDLPVPTIAAVNGYALGGGCECVLATDYRLATPDLRIGLPETKLGIMPGFGGSVRMPRMLGADSALEIIAAGKDVGADQALKIGLVDGVVKAEKLIEGAMAILRQAINGDLDWKAKRQPKLEPLKLSKIEATMSFTIAKGMVAQTAGKHYPAPITAVKTIEAAARFGREEALNLENKSFVPLAHTNEARALIGIFLNDQYVKGKAKKLTKDVETPKQAAVLGAGIMGGGIAYQSAWKGVPVVMKDINDKSLTLGMTEAAKLLNKQLERGKIDGLKLAGVISTIHPTLDYAGFDRVDVVVEAVVENPKVKKAVLAETEQKVRPDTVLASNTSTIPISELANALERPENFCGMHFFNPVHRMPLVEIIRGEKSSDETIAKVVAWASKMGKTPIVVNDCPGFFVNRVLFPYFAGFSQLLRDGADFRKIDKVMEKQFGWPMGPAYLLDVVGIDTAHHAQAVMAAGFPQRMQKDYRDAIDALFDANRFGQKNGLGFWHYKEDSKGKPKKEEDAAVDDLLAEVSQPKRDFSEEEIIARMMIPMVNEVVRCLEEGIIATPAEADMALVYGLGFPPFHGGAFRWLDTLGSAKYLDMAQQYQHLGPLYEVPEGLRNKARHNEPYYPPVEPARPVGDLKTA
What is the function of this protein?
Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle.  Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA.  It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
Protein: YOR2_COYMV
Sequence: MSNITESKGYKEALSVTNNYLAPAIGIGGATDVGLTGVTKQLNTTIYLVAKITQQIEDLQSTIKRLEERVQSLEKAKTPVVTQDPNPEIISKLSDIQISLARQRAVNPAISGVSNYTAPTIKKVDRILRVFKKFN
What are the official names of this protein?
Uncharacterized 15 kDa protein, ORF2.
Protein: HEM22_ARATH
Sequence: MTSSMFRSPCKIPSVKGFEQKSYVGLKAASYNVRVNSFKSSEVASQLQKIDSTLIWPVNALEAPPVPSKPATPLIDQPLQLSRRARRNRKCPTQRAAFQETNISPANFIYPLFIHEGEVDIPITSMPGRYMLGWRHGLIEEVARALDVGVNSVKLYPKVPEALKSPTGEEAFNDNGLIPRTVRLLKDRFPDLVIYTDVNFDEYSTTGHGGIVGEDGVILNDETIHQLRKQAVSQARAGADVVCTSEMLDGRVGAVRAALDAEGFQDVSIMSYSVKYTSSLYGRFRKVQLDKKTYQINPANSREALLEAREDEAEGADILMVKPALPSLDIIRLLKNQTLLPIGACQVSGEYSMIKAAGLLKMIDEEKVMMESLLCIRRAGADLILTYFALQAATKLCGENKRFSSN
What is the function of this protein?
Catalyzes an early step in the biosynthesis of tetrapyrroles.  Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity).
What are the official names of this protein?
Probable delta-aminolevulinic acid dehydratase 2, chloroplastic, ALADH2, Porphobilinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the ALAD family.
What are the subcellular locations of this protein?
Plastid, chloroplast.