PharMolix/UniProtQA huggingface dataset:
Protein: YIDD_LACCB
Sequence: MKQVLTWLVRGYQRFISPLLPPSCRYYPTCSTYMIQALQKHGAIKGSLMGIARILRCNPFVKGGLDPVPAFFTLRRNPHPENDLDLSDIQNLNHKLGGRHG
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DFA29_MOUSE
Sequence: MKTLVLLSALVLPCFQVQADPIQNTDEETKTEEQPEEEDQAVSVSFGGTEGSALQDVAQRRFPWCRKCRVCQKCQVCQKCPVCPTCPQCPKQPLCEERQNKTAITTQAPNTQHKGC
What is the function of this protein?
Apparent precursor of a secreted, cationic, proline- and cysteine-rich peptide that contains Cys-Pro-Xaa repeats (PubMed:2351676).  Unlike cryptdin, the proposed mature peptide region lacks the structural motif characteristic of defensins (PubMed:2351676).
What are the official names of this protein?
Alpha-defensin 29, Alpha-defensin-related sequence 1, CRS1C, Cryptdin-related protein 1C, Defensin-related cryptdin-related sequence 1.
What is the protein family that this protein belongs to?
Belongs to the alpha-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYP_GLOC7
Sequence: MRLSQMLFVTLREDPAEAEIPSHKLLLRAGYIRRIGSGIYAYLPLMWRVLQKVSQIVRQEMNATGAQECLLPQLQPSELWKESGRWDTYTKAEGIMFALEDRQERELGLGPTHEEVITFIAREMIRSYRQLPVNLYQIQTKFRDEIRPRFGLMRGREFIMKDAYSFDTDPEGLKKTYQDMDKAYRNILRRCGLAFRAVDADSGAIGGSGSQEFMVLADAGEDEVLYTDDGKYAANVEKAVSLPPDEEPSPFKNYEKRETPNTDTIEKLAQFLKCSPTVVVKNILYEAVYDNGMIVLVLVNIRGDQEVNEVKLQNELVKLAPQYHAKTIIALKVPDESAQQKWAAKSLPLGYISPDLGDDYIQGSKEIASKFVRLVDKTVVELKNFVTGANEKGYHVLGANWGKEFKLPQLIVDVRTAKAGDRAVHDRTQTLQSARGIEVGHIFQLGTKYSHAMGATYTNEQGEEMPLVMGCYGIGVSRLAQSAVEQSYDKDGIIWPVAIAPYHAIVVIPNINDPQQVEVAEKLYTELNAAGIETLLDDRDERAGVKFKDSELVGIPYRIVTGRSLKEGKLEVVERATKKSQDIPIDEVVSTIQQWVKAAL
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PS13A_ARATH
Sequence: MAALQYLESLKNTHPELGEWYNSLADLYQKKLWHQLTLKLEQFIALAVFQAGDALIQFYHNFITDFETKINLLKLAHFAVVVSRQYSEKEAAVSYLESVIEKLRATKEPRITEPIIYIETQKALFKLEQGDQKECKKILDDGKSSLDSMTDIDPSVYANFYWVSSQYHKCRQEFSDFYKSALLYLAYTSVEDLSESFKLDLAFDLSLSALLGENIYNFGELLAHPILKSLLGTNVEWLYHILQAFNHGDLVQYQELCRVHNASLIAQPALVENEKKLLEKINILCLIEIIFSRPAEDRTIPLSIIAERTKLSIEDVEHLLMKSLSVHLIEGIIDQVNGTIYVSWAQPRVLGIPQIKALRDQLDSWVDKVHTTLLSVEAETPDLVAA
What is the function of this protein?
Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
What are the official names of this protein?
26S proteasome non-ATPase regulatory subunit 13 homolog A, 26S proteasome regulatory subunit RPN9a, AtRNP9a, 26S proteasome regulatory subunit S11 homolog A.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S11 family.
Protein: H3Y2_HUMAN
Sequence: MARTKQTARKATAWQAPRKPLATKAARKRASPTGGIKKPHRYKPGTLALREIRKYQKSTQLLLRKLPFQRLVREIAQAISPDLRFQSAAIGALQEASEAYLVQLFEDTNLCAIHARRVTIMPRDMQLARRLRGEGAGEPTLLGNLAL
What is the function of this protein?
Primate-specific variant histone H3, which constitutes a core component of nucleosomes (PubMed:20819935).  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (Probable).
What are the official names of this protein?
Histone H3.X, Histone H3.Y2.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: PURA_MYCPA
Sequence: MPAIVLIGAQWGDEGKGKATDLLGGRVQWVVRYQGGNNAGHTVVLPTGENFALHLIPSGVLTPGVTNVIGNGVVVDPGVLLDELKGLEDRGVDTSRLLISADAHLLLPYHVAIDKVTERYMGNKKIGTTGRGIGPCYQDKIARIGIRVADVLDREVLTHKIEAALELKNQILVKIYNRKALDPHQVVECLLEQAEGFRHRIADTRLLLNTALEAGETVLLEGSQGTLLDVDHGTYPYVTSSNPTAGGAAVGSGIGPTRITAVLGILKAYTTRVGSGPFPTELFDENGEYLSKTGGEFGVTTGRRRRCGWFDAVIARYATRVNGITDFFLTKLDVLSSLETVPVCVGYRIDGARVNEMPMTQSDLHRAEPIYEELPGWWEDISAAREFDDLPAKARDYVLRLEELAGAHVSCIGVGPGREQAIVRRDILAARP
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIC_BURCJ
Sequence: MNANPKFLSADAHVDAAAVAPLPNSRKVYVTGSQPDIRVPMREITQADTPTGFGGEKNPPIYVYDTSGPYTDPDAKIDIRAGLPALRQRWIEARGDTEVLPGLSSQYGLERAADPATAELRFPGLHRNPRRAQAGKNVTQMHYARQGIITPEMEYIAIRENQRRAEYIESLKSSGPNGAKLAAMMGRQHPGQAFGAAAFGANALAEITPEFVRDEVARGRAIIPANINHPESEPMIIGRNFLVKINANIGNSAVTSSIGEEVDKMTWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTANRMTGIVSRGGSIMAKWCLAHHKESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELKTLGELTQIAWKHDVQVMIEGPGHVPMQLIKENMDLQLDWCKEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVKEGIITYKLAAHAADLAKGHPGAQVRDNALSKARFEFRWEDQFNIGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQDVREFAAQQGVSETEALKKGMEVKAVEFVKTGAEIYHRQ
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: MPTN_METJA
Sequence: MKLGIITIERDAVVNDLIKSCEKYEVDYKVITPSNIVAGFNLDFKLKYYKSFLDELDCCFVRNLGWDSFFRFDVLKYLNHYIPVINPPDGIDRASNKFLTSVFLELNNLPQPKTVVTESINEAIVWIDKFEEAVLKPIFGCGGEGIVRVKKELPISTKLKILNEFKEKYNTFYIQEFIKPVRNEHRDIRAFVVDDEVVAAMYRIGGENWKNNVSQGGRVEKCEITEEIEKLALKAKNALGLFYAGVDLIESEDGLKVLEVNSTPSWIGLSKVSEVNIADKLLEKIIQYVKS
What is the function of this protein?
Catalyzes the ATP or GTP-dependent addition of one L-glutamate molecule to tetrahydromethanopterin, producing tetrahydrosarcinapterin.
What are the official names of this protein?
Tetrahydromethanopterin:alpha-L-glutamate ligase, H(4)MPT:alpha-L-glutamate ligase.
What is the protein family that this protein belongs to?
Belongs to the RimK family. MptN subfamily.
Protein: SYFA_LISMO
Sequence: MLEQLQTLKSEAETQINEASDLKTLNDLRVKYLGKKGPMTEIMKQMGKLSAEERPKMGSLANEVRTALTEAISSKQQILETEAINEKLKSETIDVTLPGTAPSIGTKHLLTQVIEEMEDMFIGMGYEIAEGPEVELDYYNFEALNLPKDHPARDMQDSFYITENTLLRTQTSPVQARTMEKHDFSKGPIKVICPGKVYRRDNDDATHSHQFTQIEGLVVGENITFADLKGTLTVLAKTMFGEEREIRLRPSFFPFTEPSVEMDISCFKCGGKGCRVCKGTGWIEILGSGMVHPNVLEMSGIDSTRYSGFAFGLGPERVAMLKYAVDDIRHLYTNDLRFTKQFQSTETGEI
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_WOLWR
Sequence: MRYKITVEYNGSSFSGWQKQQHSANSIQEKIENAIFNFSGEKIALYCGGRTDAGVHALGQVAHFDMEKECELYRIRNAINYHLKSIPIVVLNAEVVDDAFHARFSAKKRYYEYRIVNRYAPAALETGYVWQVFSPLDVNIMREAAKHLLGKHDLSSFRSKDCHAANPIRTIDDIDIVQNGNHIHIKISAISFLHNQVRIIAGTLVEFGKNRTNPQEMLHILSQCKRSAAGVTAPPFGLYLVKIDY
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: DHI2_RAT
Sequence: MERWPWPSGGAWLLVAARALLQLLRSDLRLGRPLLAALALLAALDWLCQRLLPPPAALVVLAGAGWIALSRLARPPRLPVATRAVLITGCDTGFGKETAKKLDAMGFTVLATVLDLNGPGALELRARCSPRLKLLQMDLTKPEDISRVLEITKAHTASTGLWGLVNNAGLNMVVADVELSPVVTFRECMEVNFFGALELTKGLLPLLRHSRGRIVTVGSPAGDMPYPCLAAYGTSKAAIALLMDTFSCELLPWGIKVSIIQPGCFKTEAVTNVNLWEKRKQLLLANLPRELLQAYGEDYIEHLHGQFLNSLRMALPDLSPVVDAIIDALLAAQPRSRYYTGRGLGLMYFIHHYLPGGLRRRFLQNFFISHLLPRALRPGQPGPVHDTTQDPNPSPTVSAL
What is the function of this protein?
Catalyzes the conversion of biologically active 11beta-hydroxyglucocorticoids (11beta-hydroxysteroid) such as corticosterone, to inactive 11-ketoglucocorticoids (11-oxosteroid) such as 11-dehydrocorticosterone, in the presence of NAD(+) (PubMed:7649078).  Functions as a dehydrogenase (oxidase), thereby decreasing the concentration of active glucocorticoids, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids (PubMed:7649078, PubMed:34028587).  Plays an important role in maintaining glucocorticoids balance during preimplantation and protects the fetus from excessive maternal corticosterone exposure (PubMed:34028587).  Catalyzes the oxidation of 11beta-hydroxytestosterone (11beta,17beta-dihydroxyandrost-4-ene-3-one) to 11-ketotestosterone (17beta-hydroxyandrost-4-ene-3,11-dione), a major bioactive androgen (By similarity).  Catalyzes the conversion of 11beta-hydroxyandrostenedione (11beta-hydroxyandrost-4-ene-3,17-dione) to 11-ketoandrostenedione (androst-4-ene-3,11,17-trione), which can be further metabolized to 11-ketotestosterone (By similarity).  Converts 7-beta-25-dihydroxycholesterol to 7-oxo-25-hydroxycholesterol in vitro (By similarity).  7-beta-25-dihydroxycholesterol (not 7-oxo-25-hydroxycholesterol) acts as ligand for the G-protein-coupled receptor (GPCR) Epstein-Barr virus-induced gene 2 (EBI2) and may thereby regulate immune cell migration (By similarity).
What are the official names of this protein?
11-beta-hydroxysteroid dehydrogenase type 2, 11-DH2, 11-beta-HSD2, Corticosteroid 11-beta-dehydrogenase isozyme 2, NAD-dependent 11-beta-hydroxysteroid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Microsome. Endoplasmic reticulum.
Protein: COBT_DESVV
Sequence: MNHELRSVIDAINPVDQSLMAAAQAHLDNLTKPRGSLGRLEELAARLYCIAGGRRPLRVDPARVFTVAGDHGVSAEGVSPFPQEVTRQMVLNFANGGAGINVLCRTAGVDLRVVDAGCLGGPFPEHPALIQRKVAEGTASIARGPAMSLETCEKALLLGISLAEEAAADGCRCVGTGDMGISNTTPSTALYCAYLGLDPADITGPGAGLASEAVRHKVEVIRRALEVNRHIVEAGDPVATLAALGGIEIATLAGLVIGAARHGLACVIDGFISTAAFTAAWKICPDVRGYCFLSHASAEPGYRSVVDALNAQPLLHLGLRLGEGTGGALAMFLMRAAADIFNDMATFADAGVSEADD
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: ERA_ELUMP
Sequence: MTDKDFKSGFAVMAGLPNAGKSTLLNAVAGGLLSAVSPKPQMTRQNIIALSEGEKHQIIFVDTPGFLEAKYKLQEIMKGSLSQALEEDADVAVFVFDPLQEYSAHKKLISKLQNIKCPLFVLINKADTQPVEKLRKIEEQLKKDLPDIEKTFFISAKQNKGVAEFKTAVAETLPFNPPYFPQGQWTDRWERFYVAEFIREQIFNLYEKEVPYCTYVEVETFTEDLGPKNYIKAKIYVERESQKPIIIGSKGSSIAKLRVSAQKRIEEFLGRKYRLELEVSVEPQWRSSKKCLQKFGFITE
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: EFTU_RICTY
Sequence: MAKAKFERTKPHVNIGTIGHVDHGKTSLTAAITIILAKTGGAKATAYDQIDAAPEEKERGITISTAHVEYETNNRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLAKQVGVPAMVVFLNKVDMVDDPDLLELVEMEVRELLSKYGFPGNEIPIIKGSALQALEGKPEGEKAINELMNAVDSYIPQPIRATDKPFLMPIEDVFSISGRGTVVTGRVESGIIKVGEEIEIVGLKNTQKTTCTGVEMFRKLLDEGQSGDNVGILLRGTKREEVERGQVLAKPGSIKPHDKFEAEVYVLSKEEGGRHTPFTNDYRPQFYFRTTDVTGTIKLPFDKQMVMPGDNATFSVELIKPIAMQEGLKFSIREGGRTVGAGVVTRINN
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCD_RANMC
Sequence: MEKWRFNSMLSKEELEHQCGLSKSLKCTGSIGNTNGGEDLAINNMIRGWVDSDNSSNIDHLVGVSNIRSLISDDTFLVRDSNGKNYSIYFDIENQIFEIEIEGDRSFLSELESFFSSYLNLNYSYPNDGSKSDNHYYDRSMYDTQYSWNNYITSCIENYLRSEIHIDSYISSSSDNYSKSYISNYVCSGGGLNSTDSESFSIQTSANGSTFDMIGKFKNFDISPKYSHLWVQCENCYGLNYKKFFRLKLHICEQCGYHLKMSSSERIEILIDPGTWDAMDEDMVSVDPIEFHSEEEPYKDRIDSYQKKTGLTEAVQTGIGQLNGISIAIGVMDFQFMGGSMGSVVGEKITRLIEYATNGFLPLIIVCASGGARMQEGSLSLMQMAKISSASYDYQSNKKLFYVSILTSPTTGGVTASFGMLGDIIIAEPNAYIAFAGKRVIEQTLNKTVPDGSQEAEYLFQKGLFDLIVPRNLLKGVLSELFQLHGFFPLNKNFIK
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: Y3058_HALWD
Sequence: MSRSALVGNITAMLEDAGFLVSDRCAIRPKSFDVAARRGEDLVLLKILGNVDALDRMTGAEMRRLGGYLDATPLVIGVRTRDEDLKPNVVYFRHGVPVLSPDTAMDLFVEGVPPLIYAAPGGLYVNIDGDLLADEREERGWSLGRLATELGVSRRTVSKYEDGMNASIEIAIQLEEVFDEPFSSPLEVMEGAESVRDSEPTPDDPDPDADDEHVVHILTRAGFTVHPTARAPFKAVGEDDDNRRGVMSLLTGHSSFTKSAKKRARIMSSLGEVTQTRAVYFTETDAKRDAVKGTALVSCAELDAVDDPAAIRDLIRERSQKPTEA
What are the official names of this protein?
Putative HTH-type transcriptional regulatory protein HQ_3058A.
Protein: KITH_VIBCH
Sequence: MAQMYFYYSAMNAGKSTTLLQSAFNYQERGMNPLIFTAAIDDRFGVGKVSSRIGLEAEAHLFHADTDLLHVIATLHEAEPRHCILMDECQFLSKEQVYQLTEVVDKLDIPVLCYGLRTDFLGELFEGSKYLLSWADKLIELKTICHCGRKANMVIRTDEHGNAISEGDQVAIGGNDKYVSVCRQHYKEALGR
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SP5G_BACC0
Sequence: MEVTDVRLRRVNTEGRMRAIASITLDHEFVVHDIRVIDGNNGLFVAMPSKRTPDGEFRDIAHPINSGTRSKIQDAVLTEYHRLGELEEVEFEEAGAS
What is the function of this protein?
Essential for sporulation.  Interferes with or is a negative regulator of the pathway leading to asymmetric septation.
What are the official names of this protein?
Putative septation protein SpoVG, Stage V sporulation protein G.
What is the protein family that this protein belongs to?
Belongs to the SpoVG family.
Protein: RTS2_YEAST
Sequence: MADYDSAKYWSKQGARRGLQKTRYYCQICQRQCKDANGFQSHNKSPSHLRKISQVTAEDARRYNIQFEKGFLQLLKQRHGEKWIDANKVYNEYVQDRDHVHMNATMHRSLTQFVRYLGRAGKVDVDMDIDDTSENVEGPLLIRIHPSSLSSPSEDGMLRSQQEEQEVIAAELLKRQLNRAKRQTEKVYQPEMKSEISGDSTLKRVQVTFHGNGRVNKKKKKVPPRKDGIKFR
What are the official names of this protein?
Zinc finger protein RTS2.
What are the subcellular locations of this protein?
Nucleus.
Protein: SEC17_COPC7
Sequence: MAPKSAAQALFEKADKKANSSGGWFSSANSKWEEAGDLYQQAANAFKLEKQFKEAGDAFAREAECREKCKESLDAGNAWWNAAKAYKRGYPDLAIQALQQTIQHLVAGGRFRQAADREKEIAQIYLQETHDLSRACESFLRAGDWYAEEDATATANQCYKDAADLYAELEQFPQAITLYERVADHSLTSNLTKYSVKEYWLKSLLCTVALGDIVTARRNAQKYIGQDNTFVGTREFKFADALMEAVDAGDVGAYTAAVVEFDRITKLDNWKTAILLKIKRGIQEEPGLT
What is the function of this protein?
Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.
What are the official names of this protein?
Vesicular-fusion protein SEC17.
What is the protein family that this protein belongs to?
Belongs to the SNAP family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: CX049_RAT
Sequence: MGSPEEQSVPGDDFNEESTDPNKNLSLVSGPADSNEGEIRLPSPKGSNLPLVSQQDTSEAPSVVLWTGGCWPDSLVSEEERLGSPEDEKMDGLDFLSQPSVETEQQVANPETPGAKEQPSSESFCAETETGSNRRAPQASGSEEAKAASAATFLPKGLEQSRAWVSPRKSTTSRMLISENVHHPPSEPELSEELNEVQMMRVTICLKDGNHGNQAKNSGPAETGDLARHSNVQTRESFMRMPSSLLTTTRGLTSGMERQTSKELEPFSSKKKQGILWGKGGSKSNYAEAAAGVGALPKAGPRKKMTQKKKPLWDASAVTLGKAFHQWGQRLKSAPAEPATFPPISGVGLPGRSNKCSLLPLRPKQCKNFYTGKRSGAKRTKELQLVAKEDTDSTRDPGSQVQFPTCRAEPPCQSVHQEFSSGDINTRSLQDPGNSQSSGLSQRGILSKKSTPSGDQEEPVGPPAPDSEILQLHGTQGCPRCPELQKEIEDLRKQLSALQAVGEKFQTHST
What are the official names of this protein?
Uncharacterized protein CXorf49 homolog.
Protein: HAT2_YARLI
Sequence: MSATKSAGPTTLANHLDKEVKTDVLGAIDSDKLTEATQGDHKAINEEYKIWKKNSPYLYNVVIATVMDHPTLTVEWLPDLFDDITPGSMSARLMFGSHSSGLDKDYIHVASVELPTHLRPETIGLLSQQEGGTDMKQHHDAHGRHKRIAIVQSIYEDGEVNVARYNPLASKQIAAAHVTGDIHIFDRNNIMNSKEEAKPIYNLKHHTKEGWGLNWNINHADQLVSGAIDSTVAFWKIPEAASDGSCKDVTPHTVYHHDAAVNDVKFSYKMDFLIGSASDDCTLRLWDTRKPGNKAACTIKESRGINSLDFNPHSEFLVATGSADETVKVWDMRKMDTPISQLYSHCDEVTKVQWCPHQPSVLASGGHDRAILVWDIARLHDDLSSDENDEGPPELLFHHGGHSSRISDFDWHPTLPWVIASAAEDNVIQVWRMAESISNDEAVPADDVDMED
What is the function of this protein?
Regulatory subunit of the histone acetylase B (HAT-B) complex.  The complex acetylates 'Lys-12' of histone H4 which is required for telomeric silencing (By similarity).
What are the official names of this protein?
Histone acetyltransferase type B subunit 2.
What is the protein family that this protein belongs to?
Belongs to the WD repeat RBAP46/RBAP48/MSI1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MDH_HALVD
Sequence: MTKVSVIGAAGTVGAAAGYNLALRDVCDELVFVDIPKMEDKTVGQAADTNHGIAYDSNTVVTQGGYEDTAGSDVVVITAGIPRQPGQTRIDLAGDNAPIMDDIGSSLAEYNDDFVSITTSNPVDLLNRHLYETGDRDRHKVIGFGGRLDSARFRYVLSQRFDVPVKNVDATILGEHGDAQVPVFSKVRVDGNDPAFSADEKEEILGDLQESAMDVIERKGATQWGPATGVAHMVEAVLHDTGEVLPGSLVLDGEFGYEDTAFGVPVKLGSNGIEEVVEWDLDDYEADLMDDAAEKLRDQYDEIA
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily.
Protein: ARGI_STAAR
Sequence: MTKKKGIDIIGVPSTFGQRKLGVDLGPTAIRYAGLIPRLKQLDLDVNDKGDIKVSAVDIEKFQSEQNGLRNYDEIIDVTQKLNKEVSASIENNRFPLVLGGDHSIAIGSVSAISKHYNNLGVIWYDAHGDLNIPEESPSGNIHGMPLRILTGEGPKELLELNSNVIKPENIVLIGMRDLDKGERQFIKDHNIKTFTMSDIDKLGIKEVIENTIEYLKSRNVDGVHLSLDVDALDPLETPGTGTRVLGGLTYRESHFALELLHQSQSVTSMDLVEVNPLIDHNNHTAEQSVSLVGTFFGETLL
What are the official names of this protein?
Arginase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: CPFC_FRAAA
Sequence: MTASQPAGAVDALLLVSFGGPEGPDDVLPFLRNVTAGRDVPRSRLEVVAEQYRMFGGRSPLNDQNRALAEALRAELPGLPVYWGNRNWAPYLTDTVAEMAAAGVRRAACFVTSAFSSYSGCRQYRENLAAALAALPPALAVPELVKLRLFFDHPGFVEPMVDRCVAALAELPEKARTDAHLLFTAHSLPLSQARASGPRGDAYPRQLRAVAEVIAAGVERVTGVRHPVELAYCSRSGPPAVPWLEPDVGDRLVELAGAGAVGAVVVPLGFVSDHMEVAYDLDVLAAQRAAQVGLPVARAGTVGTDPRFVAMVRELVEEVRNPDLPRRALTEFGPWPQSCAAHCCVPPRQSPQHASRAVTDAAATGRRGDAAILMGNDATSTGRRGERR
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
What are the official names of this protein?
Coproporphyrin III ferrochelatase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIB7_YEAST
Sequence: MSLTPLCEDLPQFLQNYLPNAGQTENTIVPFVTLTYAQSLDARVSRGPGVRTTISHPETKTMTHYLRHHHDGILVGSGTVLADNPGLNCKWGPDPAANSPRPIIIDTKQKWRFDGSKMQELFIKRQGKPPIVVVTSEPIIKEQHVDYAICPINDTTKLVDWKKLFEILKEEFNIRSVMVEGGANVINQLLLRSDIVNSLIITIGSTFLGSSGTEVSPPQTVNLKDMSWWKGITDVVLCARLADD
What is the function of this protein?
Catalyzes an early step in riboflavin biosynthesis, the NADPH-dependent reduction of the ribose side chain of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, yielding 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate.
What are the official names of this protein?
2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase, DAROPP reductase, DARP reductase, 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one reductase, 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate synthase, DARIPP synthase.
What is the protein family that this protein belongs to?
Belongs to the HTP reductase family.
Protein: RL20_LEPCP
Sequence: MPRVKRGVTARARHKKVLALAKGFRGRRKNVYRIAKQAVMKAGQYAYRDRRAKKRVFRRLWIARINAASRSLGLTYSKFIAGLKKAQIDIDRKVLSDMAIHDPAAFGSIVDKVKAQLA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: RL33_BURVG
Sequence: MAKGARDKIKLESTAGTGHFYTTTKNKRNMPEKMAIKKFDPVVRKHVEYKETKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: SSI_STRGI
Sequence: YAPSALVLTVGKGVSAATVTPERAVTLTCAPGPSGTHPAADSACADLAAVGGDLDALTRSEGVMCPMIYDPVLLTVDGVWQGERVSYERVFSNECEMNAHGSSVLAF
What is the function of this protein?
Strong inhibitory activity toward subtilisin.
What are the official names of this protein?
Alkaline protease inhibitor 2C', API-2C'.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I16 (SSI) family.
What are the subcellular locations of this protein?
Secreted.
Protein: HSLV_CUPNH
Sequence: MEQYHGTTIVSVRRGNQVALGGDGQVTLGNIVMKGTARKVRRIYNGKVLVGFAGSTADAFSLLDRFEAKLEKYQGNLTRAAVDLAKDWRSDRALRRLEAMLITADRDTTLVITGNGDVLDPEGGIAAIGSGGAYAQSAAKALAENTEMAPKDVVEKALTIAGELCIYTNTNFVIETLE
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.