PharMolix/UniProtQA huggingface dataset:
Protein: HUTI_RHOJR
Sequence: MTANTSRSTVLTGIGTLVTNDPTVGEGPLGLIRDAAVVFDGGVVAWVGSADSAPAGDVGHDLDGRAVLPGFVESHSHLVFGGERAEEFAARMAGQPYAAGGIRNTIEATRNATDEQLQANTRRLLDESLRSGSTTVECKTGYGQTVAHELRSTRIAASLTDEVTLLAAHVPPPEYAGRADDYVAMVCSEMIDACAPQAKWIDVFCETGAFDRDQAHAVLTAGMAKGLIPRVHGNQLREGPGVQLAVELGAASVDHVCYTTQADIDALAQSSTVATLLPGADFSTRNKYPDARALLDAGVTVALGADCNPGTSYTTSLPFCIAIAVRDMHMTPDEAIWAATAGGARALQRADVGVLRPGARADVLALDAPSYLHLAYRPGVPLVSDVWRGGELAWSAHTGHEKARALR
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDD_THEPX
Sequence: MKNVVIFLIKLYQRYISPMKPRSCRFYPTCSQYSIEAISKYGLLKGGIMSIWRILRCNPFNPGGYDPVK
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: KITM_HUMAN
Sequence: MLLWPLRGWAARALRCFGPGSRGSPASGPGPRRVQRRAWPPDKEQEKEKKSVICVEGNIASGKTTCLEFFSNATDVEVLTEPVSKWRNVRGHNPLGLMYHDASRWGLTLQTYVQLTMLDRHTRPQVSSVRLMERSIHSARYIFVENLYRSGKMPEVDYVVLSEWFDWILRNMDVSVDLIVYLRTNPETCYQRLKKRCREEEKVIPLEYLEAIHHLHEEWLIKGSLFPMAAPVLVIEADHHMERMLELFEQNRDRILTPENRKHCP
What is the function of this protein?
Phosphorylates thymidine, deoxycytidine, and deoxyuridine in the mitochondrial matrix (PubMed:9989599, PubMed:11687801).  In non-replicating cells, where cytosolic dNTP synthesis is down-regulated, mtDNA synthesis depends solely on TK2 and DGUOK (PubMed:9989599).  Widely used as target of antiviral and chemotherapeutic agents (PubMed:9989599).
What are the official names of this protein?
Thymidine kinase 2, mitochondrial, 2'-deoxyuridine kinase TK2, Deoxycytidine kinase TK2, Mt-TK.
What is the protein family that this protein belongs to?
Belongs to the DCK/DGK family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: Y414_HAEIN
Sequence: MPIGGDVKADQETSGSRSIKRIGFGFIGGIGYDITPNITLDLGYRYNDWGRLENVRFKTHEASFGVRYRF
What are the official names of this protein?
Uncharacterized protein HI_0414.
What is the protein family that this protein belongs to?
Belongs to the opacity porin family.
Protein: RECX_BACC1
Sequence: MAVITKIEVQKRSKERFNIYIDKGQGEEYGFSVNEVILIKHGLQKGLEIDEIALGNILYNEEVQKAYLQAISYLSYQMRTKLEIEDFLRKKEVGQAIISEVVSKLLHDRYINDKEYAILYTRTQSNVNRKGPTVIKRELLNKGVQDLIITHSLQEYPKEKQIENALILIEKKKKSYQKHSFLQMKLKLDEMLVRKGYSRDVIQICLEELKDEKDDEKQQEALHYHGNKYYEKYKKYDGWTFENKMKQALYRKGFSIDEIEIFLQMKREEG
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPX_BACSU
Sequence: MERSLSMELVRVTEAAALASARWMGRGKKDEADEAATSAMRDVFDTVPMKGTVVIGEGEMDEAPMLYIGEKLGNGYGPRVDVAVDPLEGTNILASGGWNALTVIAVADHGTLLNAPDMYMQKIAVGPEAVGCIDIEAPVIDNLKAVAKAKNKDVEDVVATILNRERHAKIISELREAGARIKLINDGDVAGAINTAFDHTGVDILFGSGGAPEGVLSAVALKALGGEIIGKLLPQSEEEITRCHKMGLDLSKVLRMEDLVKGDDAIFAATGVTDGELLKGVQFKGSVGTTESLVIRAKSGTVRFVDGRHSLKKKPNLVIRP
What is the function of this protein?
Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate.  Can functionally substitute for the FBPase class 3 (Fbp) of B. subtilis.
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 2, FBPase class 2, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 2.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_CUPTR
Sequence: MQTALLKPKIIAVEPLGDHHAKVVMEPFERGYGHTLGNALRRVLLSSMVGYAPTEVTIAGVVHEYSTIDGVQEDVVNLLLNLKGVVFKLHNRDEVTVSLRKDGEGVVTAADIELPHDVEIINPNHVIAHLSAGGKLDMQIKVEQGRGYVPGNVRKFGDESGKVIGRIVLDASFSPVRRVSYAVESARVEQRTDLDKLVMNIETDGVISPEEAIRQSARILVDQLSVFAALEGTESAAEAASSRTPQIDPILLRPVDDLELTVRSANCLKAENIYYIGDLIQRTENELLKTPNLGRKSLNEIKEVLASRGLTLGMKLENWPPAGLEK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: EFG_LACCB
Sequence: MANKREFPLDRTRNIGIMAHIDAGKTTTTERILYYTGKIHKIGETHEGASQMDWMPQEQERGITITSAATTAFWKDHRVNIIDTPGHVDFTIEVERSLRVLDGAITVLDAQSGVEPQTENVWRQATTYGVPRLVFVNKMDKIGADFDYSMTTLHDRLQANAHAVQMPIGAEDKFEGVIDLIEMKADLYDEDELGTKWDTVDVPDDYKEAAQKAHNDLIEAVADVDDGIMDKYLEGEEISNAELKAAIRKATINLEFYPVLAGSAFKNKGVQMLLDAVIDYLPSPLDVRPYHATDPDTGDAVELTAGDDKPFAALAFKVATDPFVGRLTYIRVYSGTLEAGSYVLNATKDNRERVGRLLQMHSNHREEIPEVFSGDIAAAIGLKNTTTGDSLTDVDHPLILESLDVPDPVIQVSIEPDSKEDQDKLDVGLQKLSEEDPTFKAETNPETGETLIAGMGELHLDIMVDRLKREFKVAAKVGEPQVAYRETFTKETSAQGKFVRQSGGKGQYGDVWIEFTPNEEGKGFEFENAIVGGVVPREYIPAVEQGLKEAMANGVLAGYPLIDVKAKLYDGSYHEVDSSEAAFKVAASMALKNASKSAGAVILEPIMHVEVVAPEEYLGDVMGQITARRGRVEGMEARGNAQLVNSMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEAVPKSIQAEIIKKNGGGVATKD
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EXAE_PSEPU
Sequence: MGILLVDDHPMIRLGLAHFLGEGLNGLPVREAGSGEEALQQVQEELPGLVIMDFDLPGISGLETTRRLRQRLPQLRVLFFSEHTELGLVRQALDAGACGFLSKAAAPAVVLEAVRRVLAGHAYIEQPLATQLACQPHPGQGGGNARLQGLTQREIEVFLMLAKGTPTRLIAQQLCISAKTVSNYLTLLKSKLQVSSHAELVHLAIEAGLLRIAA
What is the function of this protein?
Positive regulator of the expression of the gene qedA and the activity of ADH I but does not affect the activities of ADH IIB or ADH IIG.
What are the official names of this protein?
Transcriptional activator protein ExaE.
Protein: H2AZ_PHANO
Sequence: MAGGKGKTGGKTGGKGDSHVKTTKSHSAKAGLQFPCGRIKRHLRTITRQKTRIGAKASIYLTAVLEYLTAEVLELAGNAAKDLKVKRITPRHLQLAIRGDEELDTLIRATIAFGGVLPHINRALLLKVEQKKKGAKVEA
What is the function of this protein?
Variant histone H2A which can replace H2A in some nucleosomes.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.  This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activation signal is received.  Near telomeres, it may counteract gene silencing caused by the spread of heterochromatin proteins.  Required for the RNA polymerase II and SPT15/TBP recruitment to the target genes.  Involved in chromosome stability (By similarity).
What are the official names of this protein?
Histone H2A.Z.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: SYI_SULNB
Sequence: MDFKETLLLPKTDFPMRGNLPANEPKKYKTWFDTNIYEQMKAKREGAELFTLHDGPPYANGDIHIGHALNKILKDIILKYNYFQGKAVRMTPGWDCHGLPIEQKVEEKLGKSKKEAMPTEKFRELCRAHAGKFVDIQRDEFKSLGVVADWENPYVTMDFKFEANIYRTLCEVAKRGLLVERHKPIFWSWAARTALADAEVEYEDKEDYSIYVHFELSDAAKEKLGLEGKAGLVIWTTTPWTLPANTGISINPDEMYVLTDDGHIVADARYDAMIEEGVVAGHASRKIAATELDGLLAINPLNERPSKVVLGEHVMMDGGTGCVHTAPGHGEDDYKVGLENGLEVVMPVDERGCYDESVVGLDLLPDAEKFVGMHIFKANEPILELLGDNLLKVSKFTHSYPHCWRTKKPLIYRATNQWFISIDDAAKGSDKTLREAAVDAIDSVDFYPASSKNRLKPMVEGRPDWCISRQRSWGVPIAFFRVKSTKAVIFDEDVLEHVASLFDEHGADAWYSMSIAELLPAGSKYDPADLEKIEDILDVWFDSGSTWNSVLSSGNYDAGNYPASLYLEGSDQHRGWFQSSLLLSSAINGIAPYETIITHGFTMDAKGEKMSKSKGNVVAPEKVVKQFGSEILRLWVALSDYQNDQKISDDILKQTAEQYRKIRNTFRFLLANVNDLDALVSADAYGELDRWILNKADDVFASVKESFETYDFLKGFATLNHFITNELSGIYMDVTKDRLYCEAKDSDVRRATQSAMALISKAMLGLIAPVLTYTADEILAYAPAIFKGDIENVFDLVYEAVPETAASFDDAILLEAREKFSEAIDSLKKEKVIKATLELEIAGDRDLLPISDDKDLEDWFVVSAVKESSKGEQVASFKVEGRTFTVHKAMMAKCPRCWRFTSTSEDCLCERCAKVVGA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPR83_RAT
Sequence: MNVPPVLLLFLLSSVRATEQPQVVTEHPSMDAALTGANASHFWANYTFSDWQNFVGRRRYGAESQNPTVKALLIVAYSFIIVFSLFGNVLVCHVIFKNQRMHSATSLFIVNLAVADIMITLLNTPFTLVRFVNSTWVFGKGMCHVSRFAQYCSLHVSALTLTAIAVDRHQVIMHPLKPRISITKGVIYIAVIWVMATFFSLPHAICQKLFTFKYSEDIVRSLCLPDFPEPADLFWKYLDLATFILLYLLPLFIISVAYARVAKKLWLCNTIGDVTTEQYLALRRKKKTTVKMLVLVVVLFALCWFPLNCYVLLLSSKAIHTNNALYFAFHWFAMSSTCYNPFIYCWLNENFRVELKALLSMCQRPSKPQEDRLPSPVPSFRVAWTEKSHGRRALLANHHLPSSQIQSGKTDLSSVEPTVAVS
What is the function of this protein?
G-protein coupled receptor for PEN, a neuropeptide produced from the precursor protein, proSAAS (encoded by PCSK1N).  Acts through a G(i)- and G(q)-alpha-alpha-mediated pathway in response to PEN.  Plays a role in food intake and body weight regulation.  May contribute to the regulation of anxiety-related behaviors.
What are the official names of this protein?
G-protein coupled receptor 83, Glucocorticoid-induced receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Colocalizes with GPR171 in the paraventricular nucleus. Colocalizes with the ghrelin receptor GHSR1A in the hypothalamus.
Protein: RL31B_TROWT
Sequence: MKSDIHPEYGYVVFKDLASSEMFLTRSVLKPEKQIEWNDGNHYPLFEVEISSASHPFYTGQQRILDSEGRVEKFYARYKKQSQ
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: Y1684_ARATH
Sequence: MFSTHHVSRLLIPLLFFFLFCCFSSTFAQDDITNPVEVRALRVIKESLNDPVHRLRNWKHGDPCNSNWTGVVCFNSTLDDGYLHVSELQLFSMNLSGNLSPELGRLSRLTILSFMWNKITGSIPKEIGNIKSLELLLLNGNLLNGNLPEELGFLPNLDRIQIDENRISGPLPKSFANLNKTKHFHMNNNSISGQIPPELGSLPSIVHILLDNNNLSGYLPPELSNMPRLLILQLDNNHFDGTTIPQSYGNMSKLLKMSLRNCSLQGPVPDLSSIPNLGYLDLSQNQLNGSIPAGKLSDSITTIDLSNNSLTGTIPTNFSGLPRLQKLSLANNALSGSIPSRIWQERELNSTESIIVDLRNNGFSNISGRSDLRPNVTVWLQGNPLCSDGNLLRLCGPITEEDINQGSTNSNTTICSDCPPPYEFSPEPLRRCFCAAPLLVGYRLKSPGFSDFVPYRSEFEQYITSGLSLNLYQLRLDSFQWQKGPRLRMYLKFFPVFGSNANNSFIFNRSEVRRIRGMFTGWNIRDEDLFGPYELMNFTLLDVYRDVFPSASPSGLSNGAVAGIVLGSVAAAVTLTAIIALIIMRKRMRGYSAVARRKRSSKASLKIEGVKSFTYAELALATDNFNSSTQIGQGGYGKVYKGTLGSGTVVAIKRAQEGSLQGEKEFLTEIELLSRLHHRNLVSLLGFCDEEGEQMLVYEYMENGTLRDNISVKLKEPLDFAMRLRIALGSAKGILYLHTEANPPIFHRDIKASNILLDSRFTAKVADFGLSRLAPVPDMEGISPQHVSTVVKGTPGYLDPEYFLTHQLTDKSDVYSLGVVLLELFTGMQPITHGKNIVREINIAYESGSILSTVDKRMSSVPDECLEKFATLALRCCREETDARPSMAEVVRELEIIWELMPESHVAKTADLSETMTHPSSSSNSSIMKHHYTSMDVSGSDLVSGVAPSVAPR
What are the official names of this protein?
Probable LRR receptor-like serine/threonine-protein kinase At1g06840.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: MNTP_CHRSD
Sequence: MNPASLILLAFAMSTDAFAASIGRGAELRKVRLLSALRIGAVFGVVEAIMPLLGWALGHVAMRFVSGVDHWIAFVMLALLGGHMIWAGVKKEDCAAIKAAETQPENRSIWLIAFTALATSIDAMAVGITLALTDINIIAASVAIGLATALMVTLGTLLGRAIGTIVGKWAEILGGLILIGIGIAVLYEHLAGLASA
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ZER1_HUMAN
Sequence: MASDTPESLMALCTDFCLRNLDGTLGYLLDKETLRLHPDIFLPSEICDRLVNEYVELVNAACNFEPHESFFSLFSDPRSTRLTRIHLREDLVQDQDLEAIRKQDLVELYLTNCEKLSAKSLQTLRSFSHTLVSLSLFGCTNIFYEEENPGGCEDEYLVNPTCQVLVKDFTFEGFSRLRFLNLGRMIDWVPVESLLRPLNSLAALDLSGIQTSDAAFLTQWKDSLVSLVLYNMDLSDDHIRVIVQLHKLRHLDISRDRLSSYYKFKLTREVLSLFVQKLGNLMSLDISGHMILENCSISKMEEEAGQTSIEPSKSSIIPFRALKRPLQFLGLFENSLCRLTHIPAYKVSGDKNEEQVLNAIEAYTEHRPEITSRAINLLFDIARIERCNQLLRALKLVITALKCHKYDRNIQVTGSAALFYLTNSEYRSEQSVKLRRQVIQVVLNGMESYQEVTVQRNCCLTLCNFSIPEELEFQYRRVNELLLSILNPTRQDESIQRIAVHLCNALVCQVDNDHKEAVGKMGFVVTMLKLIQKKLLDKTCDQVMEFSWSALWNITDETPDNCEMFLNFNGMKLFLDCLKEFPEKQELHRNMLGLLGNVAEVKELRPQLMTSQFISVFSNLLESKADGIEVSYNACGVLSHIMFDGPEAWGVCEPQREEVEERMWAAIQSWDINSRRNINYRSFEPILRLLPQGISPVSQHWATWALYNLVSVYPDKYCPLLIKEGGMPLLRDIIKMATARQETKEMARKVIEHCSNFKEENMDTSR
What is the function of this protein?
Serves as substrate adapter subunit in the E3 ubiquitin ligase complex ZYG11B-CUL2-Elongin BC (PubMed:17304241, PubMed:31273098).  Acts redudantly with ZYG11B to target substrates bearing N-terminal glycine degrons for proteasomal degradation (PubMed:33093214).  Involved in the clearance of proteolytic fragments generated by caspase cleavage during apoptosis since N-terminal glycine degrons are strongly enriched at caspase cleavage sites.  Also important in the quality control of protein N-myristoylation in which N-terminal glycine degrons are conditionally exposed after a failure of N-myristoylation (PubMed:31273098).
What are the official names of this protein?
Protein zer-1 homolog, Hzyg, Zyg-11 homolog B-like protein, Zyg11b-like protein.
What is the protein family that this protein belongs to?
Belongs to the zyg-11 family.
Protein: GLGB_SALPA
Sequence: MSSRIDRDVINALIAGHFADPFSVLGMHQTQAGLEVRALLPDATDVWVIEPKTGRKVGKLECLDARGFFCGVLPRRKNFFRYQLAVTWHGQQNLIDDPYRFGPLMQEMDAWLLSEGTHLRPYETLGAHADTMDGVTGTRFSVWAPNARRVSVVGQFNYWDGRRHPMRLRKESGIWELFIPGAHNGQLYKFELLDANGNLRIKADPYAFEAQMRPETASMICGLPEKVTPSEERQKANQFDAPISIYEVHLGSWRRHTDNNFWLSYRELADQLVPYAKWMGFTHLELLPVNEHPFDGSWGYQPTGLYAPTRRFGTLDDFRYFINAAHAAGLNVILDWVPGHFPSDEFSLAEFDGTHLYEHSDPREGYHQDWNTLIYNYGRREVSNYLVGNALYWMERFGIDALRVDAVASMIYRDYSRKEGEWIPNEFGGRENLEAIEFLRNTNRIIGEQVPGAVSMAEESTDFSGVTRPPETGGLGFWYKWNLGWMHDTLDYMKLDPVYRQYHHDKLTFGMLYNHTENFVLPLSHDEVVHGKKSILDRMPGDAWQKFANLRAYYGWMWAFPGKKLLFMGNEFAQGREWNHDASLDWHLLEGGDNWHHGVQRLVRDLNHTYRHHKALHELDFDAYGFEWLVVDDNERSVLIFVRRDKAGNEIIVASNFTPVPRHDYRFGINQPGRWREILNTDSMHYHGSNTGNGGVVHSDEIESHGRQHSLNLTLPPLATIWLMREGE
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: CD37L_HUMAN
Sequence: MEQPWPPPGPWSLPRAEGEAEEESDFDVFPSSPRCPQLPGGGAQMYSHGIELACQKQKEFVKSSVACKWNLAEAQQKLGSLALHNSESLDQEHAKAQTAVSELRQREEEWRQKEEALVQREKMCLWSTDAISKDVFNKSFINQDKRKDTEDEDKSESFMQKYEQKIRHFGMLSRWDDSQRFLSDHPYLVCEETAKYLILWCFHLEAEKKGALMEQIAHQAVVMQFIMEMAKNCNVDPRGCFRLFFQKAKAEEEGYFEAFKNELEAFKSRVRLYSQSQSFQPMTVQNHVPHSGVGSIGLLESLPQNPDYLQYSISTALCSLNSVVHKEDDEPKMMDTV
What is the function of this protein?
Co-chaperone that binds to numerous proteins and promotes their interaction with Hsp70 and Hsp90.
What are the official names of this protein?
Hsp90 co-chaperone Cdc37-like 1, Hsp90-associating relative of Cdc37.
What is the protein family that this protein belongs to?
Belongs to the CDC37 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTH_ANASK
Sequence: MKLVVGLGNPGEEYARTRHNVGFVVADRLAQLAGASFSAKKFAAELAEARLGPERVWIMKPQTYMNHSGEAVGAALRFWKLGLDDLVVVHDDLELDPYRVQLKVGGGHGGHNGVKSVNAHVGSPEYARVRVGVGRPPPRMDPADYVLGKFAKGEDAELDLCVEQAVEATRLAVELGAARAMNQVNRRSRAAE
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SF18_HELAN
Sequence: LVFVVAISDIATVNGKICEKPSKTWFGNCKDTDKCDKRCIDWEGAKHGACHQREAKHMCFCYFDCDPQKNPGPPPGAPGTPGTPPAPPGKGEGDAPHPPPTPSPPGGDGGSGPAPPAGGGSPPPAGGDGGGGAPPPAGGDGGGGAPPPAGGDGGGAPPPGA
What is the function of this protein?
Anther-specific cell wall protein which could contribute to the cell wall architecture of epidermal anther cells via intermolecular disulfide bridges.
What are the official names of this protein?
Anther-specific protein SF18, Defensin-like protein.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: VMA21_CANGA
Sequence: MAVDVPKSVIKKLVFFTVAMVVLPLLTFFTLQHLTSNTIISGGLAALMANVVLVGYIIAAFTEDTTEYAPEGKESKKE
What is the function of this protein?
Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.
What are the official names of this protein?
Vacuolar ATPase assembly integral membrane protein VMA21.
What is the protein family that this protein belongs to?
Belongs to the VMA21 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein.
Protein: UREG_STRT1
Sequence: MTKRTVIIGVGGPVGSGKTLLLERLTRRMSDLNLAVITNDIYTKEDALFLAKNSSLDEDRIIGVETGGCPHTAIREDASMNFEAIETLQERFNHDLDVIFLESGGDNLAATFSPDLVDFTIYIIDVAQGEKIPRKAGQGMIKSDLFLINKTDLAPYVGANLDRMREDTLHFRNEDSFIFTNLNNDDNVKEVEEWIRKNFLLEDL
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLHD_ECOSM
Sequence: MHTSELLKHIYDINLSYLLLAQRLIVQDKASAMFRLGINEEMATTLAALTLPQMVKLAETNQLVCHFRFDSHQTITQLTQDSRVDDLQQIHTGIMLSTRLLNDVNQPEEALRKKRA
What is the function of this protein?
Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region.  Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes.  Also regulates genes whose products function in a variety of physiological pathways.
What are the official names of this protein?
Flagellar transcriptional regulator FlhD.
What is the protein family that this protein belongs to?
Belongs to the FlhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBB_CUCSA
Sequence: MGLPWYRVHTVVLNDPGRLLSVHIMHTALVAGWAGSMALYELAVFDPSDPVLDPMWRQGMFVIPFMTRLGITNSWGGWSITGGTITNPGIWSYEGVAGAHILFSGLCFLAAIWHWVYWDLEIFSDERTGKPSLDLPKIFGIHLFLSGLGCFGFGAFHVTGLYGPGIWVSDPYGLTGRVQAVNPAWGVEGFDPFVPGGIASHHIAAGTLGILAGLFHLSVRPPQRLYKGLRMGNIETVLSSSIAAVFFAAFVVAGTMWYGSATTPIELFGPTRYQWDQGYFQQEIYRRVSTGLAENQSLSEAWSKIPEKLAFYDYIGNNPAKGGLFRAGSMDNGDGIAVGWLGHPVFRDKEGRELFVRRMPTFFETFPVVLVDGDGIVRADVPFRRAESKYSVEQVGVTVEFYGGELNGVSYSDPATVKKYARRAQLGEIFELDRATLKSDGVFRSSPRGWFTFGHASFALLFFFGHIWHGARTLFRDVFAGIDPDLDTQVEFGAFQKLGDPTTKRV
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP47 reaction center protein, PSII 47 kDa protein, Protein CP-47.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: CEP72_MOUSE
Sequence: MAPGQRLVLCEETVRERSGLGPHRDLAELRSLSIPGTYQEKITHLGNSLMHLTALKSLDLSRNSLVSLEGIQYLVSLESLNLYYNCISSLAEVFRLHTLLELQDVDFRLNPVVKNESDYRLFVVHMLPKLRQLDDRPVRESERKASQLHFAPEDSLNSKENFSTTLTVGRPHHLRNRCTETSAKKCLVMDADDEAVLNLIAECEWDLSNPPGNMSSSQKEHEADLHYAQESRHLLSPLSIQHQCGDSARRGHEKKKVTSRGCPGHSPQDQLCGELPLQHGLPEACHMHVQHARITSQPDSVDVEDCASSAQKSSLSSQKTVNPLPVPEKYRKRRMPGGRFQVPSDRECLSFLERADGPSSLEDSLSRQDGLEGQSQVALSHSEALEAEERTSHGTSDPRVLSPKLCSAAVPERRSTLEVALLEALLDLIDRCSSGSGSLHGNEAFLAQAKHVLSSLQEFTATRDSSALEKEGIGYLSLENKTLQSRLAEQQQQYTATVTKMTAELNNTKRELDTLRQHLDKSLEENSHLKSLLYNVKKEVKTADTSTALTLQITGLQASMKQLSGEVVELKQHVEHYDKIQELTQMLQESHSSLVSTNEHLLQELSRTRAQHRAEVEQMRWSFQEFKKTTALIPHRSSRRGGRQSC
What is the function of this protein?
Involved in the recruitment of key centrosomal proteins to the centrosome.  Provides centrosomal microtubule-nucleation activity on the gamma-tubulin ring complexes (gamma-TuRCs) and has critical roles in forming a focused bipolar spindle, which is needed for proper tension generation between sister chromatids.  Required for localization of KIZ, AKAP9 and gamma-tubulin ring complexes (gamma-TuRCs) (By similarity).  Involved in centriole duplication.  Required for CDK5RAP22, CEP152, WDR62 and CEP63 centrosomal localization and promotes the centrosomal localization of CDK2 (By similarity).
What are the official names of this protein?
Centrosomal protein of 72 kDa, Cep72.
What is the protein family that this protein belongs to?
Belongs to the CEP72 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Note=Localizes to the centrosome and centrosome-surrounding particles throughout the cell cycle. These particles disappear after microtubules are depolymerized using nocodazole, suggesting that CEP72-associating particles localize in a microtubule-dependent manner (By similarity).