PharMolix/UniProtQA huggingface dataset:
Protein: MLT1_CANAL
Sequence: MNESNRELILGLSPVHLSLFNSESLLHTFNFFGVGDGQANIASNYVTASKFVIPQPLYSPHGNALNPAFVELIGQAVNTFFAIFMLFQLTRLLLTKKKSHRIYTPTPFSQTLKISLVLLQVILVASLYFLNKNSYFIGGIAATVLALILHLVEFRRSPIAIESLLTYWSANTAFTFAVFIQDSYSKHKIYANSGPAYVIEIISLVNSFLIFVFEVGYYKPGFEITNEKFLDTVNLFSYFTFYYLQPLINKIYATDDVQLTDLPDILGNITCDDTKAKVAKAWEEELKRTKKPGLVSKVWSFVTRRKVNSKPQMFLAIAKAFFDKFAISITLAIIVTGLSFLQPFLLRKFIQFFSTYFYSVEKPPIIIGYFWASVMFLTSVANFIAFNQAFKTQFDLGYEIQSSLTTLIYEKALRLSPQSRKNKPTGDIINHITMDIDIIFWFCWQLGEYLASPLKLAVCLAALYKLFSNATWAGVITAIIVAPLATLVNASMSKNYIQLMKDKDERTSLITEILNSAKSIKFYSWEKPMLARLSHIRNDRELNNIKKIGVVSALAQFLWSCIPFFISCATYATYAYFYNVPLTPDIVFPALALFDLLSEPMLLIPSFIVEVIEVSTSLARIGELLCLDELADDQHGYVKRDPEPNDNSIYSVIVKDATFVWSEETQQKQYTDEESEVQEVPASNVALKNINFSARKGELACIVGKVGSGKSTLIKAILGDVPIKIPSYSDDSTNPTPSVETFGSIAYCPQNPWILNGTVKENILFGHKYDAEFYQKTIDACELISDFKNLPDGDQTVVGEKGISLSGGQKARISLARSVYTRADIYLLDDILSAVDAHVGKNIIKKVLSNEGLIGNRCRILATNSVPVLHEANDIYLIAGGAFVEHGKFKEVMKRNGDLAKLIKEYGRKKDEPTEEETTEASTEPKEEDHSNGKSDTAVHDELDTDELVDEIVDYVGEQNRGVVEQAILRRASVVSYGHNYENDEADNGQIRKTRHEQEESRKGTVPWDIFKQYIIACDYKYFSFYVAATFSVVLISAGEKYLLSYWSQLNSEQNDTVEPVFFLGTYATLGVVSGFLTYMGALVIWSYCIVKGSTYFHNKMAESVLRSPMSFFDTTPIGRILNRFTEDIGKIDMNLPWTIISFITTLLNGFVTFGVILSFLPLMLVVIVSLLFVYNYFRIRFVPTTRELKRLESIAKSPVLATIQESINGVETIKAFHQRERFVYKSKKLIDEKTLIGVVQQNCNRWLSMRLQTISSSIMFFTALLAVVTLGGKHPILPSILGFVMTYSMSITYILNSLVRIWAEMQAGGVAIERIIEYCDLPSEAPMIIEDKRPQDSWPAHGVVKFKKYSTAYRKHLDPVLREIELTINSKEKVGIVGRTGAGKSSLTLALFRIIEATGGNIEIDGVDTSQIGLYDLRHHLTIIPQEAHTFRASVRENLDPFGEYSDDKLWKVLELAHLKEHVTKMETDPTEEEKKASKNPDELSKKVGLDAQIEEGGSNLSSGQKQLLCLARALLNETSKILVLDEATAAVDFQTDKIIQETIRTEFKDKTILTIAHRIDTIMDSDKILVLDSGKVAEFDSPQNLLKNKDSIFYSLAKEGGYID
What is the function of this protein?
Vacuolar multi-drug resistance ABC transporter that may be involved in the transport of bilirubin and glutathione conjugates (By similarity).  Plays an important role in virulence.
What are the official names of this protein?
Multiple drug resistance-associated protein-like transporter 1, MRP-like transporter 1, Vacuolar multi-drug resistance ABC transporter MTL1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Associates with lipid rafts in a RTA2-dependent manner.
Protein: ARHGC_MOUSE
Sequence: MSGTQSTITDRFPLKKPIRHGSILNRESPTDKKQKVERSSSHDFDPTDSSSKKTKSSSEESRSEIYGLVQRCVIIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGTLVTHSNHLEVVKLIRSGSYVALTVQGRPPGSPQIPLADSEVEPSVTGHMSPIMTSPHSPGAAGNMERITSPVLVGEENNVVHNQKVEILRKMLQKEQERLQLLQEDYNRTATQRLLKEIQEAKKHIPQLQEQLSKATGSAQDGAVIAPSRPLGDALTLSEAEADPGDGLCRTDWSSGDASRPSSDSADSPKSSLRERSYLEEAPERSEGVQDAEPQSLVGSPSTRGAPHIIGAEDDDFGTEHEQINGQCSCFQSIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKQTNSKETRRVFLEFHQFFLDRSAHLKVPVPEEISVDLEKRRPELIPEDLHRLYIQTMQERVHPEVQRHLEDFRQKRSMGLTLAESELTKLDAERDKDRGTLEKERACAEQIVTKIEEVLMTAQAVEEERSSTMQYVILMYMKYLGVKVKEPRNLEHKRGRIGFLPKIKQSMKKDREGEEKGKRRGFPSILGPPRRPSRHDNSAIGRAMEIQKSRHPKHLSTPSSVSPEPQDPAKLRQSGVANEGTDTGYLPASSMSSATSGTALSQEGGRENDTGTKQVGEASAPGDCLDSTPRVPTTVFDFPPPLLDQVQEEECEVERVAEHGTPKPFRKFDSIAFGESQSEDEQFENDLETDPPNWQQLVSREVLLGLKPSEIKRQEVINELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSNLEDILQLHVGLNEQMKAVRKRNETSVIDHIGEDLLIWFSGPGEEKLKHAAATFCSNQPFALEMIKSRQKKDSRFHTFVQDAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYTEWPPEREKVKKAADHCRQILNYVNQAVREAENKQRLEDYQRRLDTSNLKLSEYPNVDELRNLDLTKRKMIHEGPLVWKVNRDKSIDLYTLLLEDILVLLQKQDDRLVLRCHSKILASTADSKHTFSPVIKLSTVLVRQVATDNKALFVISMSDNGAQIYELVAQTVSEKTVWQDLICRMAASVKEQSTKPIPLPQPPPCEGDNDEEEPAKLKVEHHDLSVAGLQSPDRVLGLESPLISSKPQSHSLNTPGKSAAEHLFVTATQFAKEQHANGALKEGDGGYPVTIPGPHLPVSEERWALDALRNLGLLKQLLVQQLGLTEKSTQEDWQSFSRYGPASEEVQADSGIRDLENVKACHAREGQMSFKTGTGDIATCDSPRTSTESCAAQDSVILASQDSQASNVLVMDHMILTPEMPPAEPEGGLDESGEHFFDAREAHSDDNPSEGDGAVKKEEKDVNLRISGNCLILDGYDAVQESSTDEEVASSFPLQPVTGIPAVDSSHQQQHSPQNVHPEGPVSPFTPEFLVQRHWRAMEDTCFEIQSPSCTDSQSQILEYIHKIEADLEHLKKVEESYALLCQRLAGSALPDKLSDKS
What is the function of this protein?
May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13).  Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13 (By similarity).
What are the official names of this protein?
Rho guanine nucleotide exchange factor 12, Leukemia-associated RhoGEF.
What are the subcellular locations of this protein?
Cytoplasm. Membrane. Note=Translocated to the membrane upon stimulation.
Protein: NANT_ECO27
Sequence: MSTTTQNIPWYRHLNRAQWRAFSAAWLGYLLDGFDFVLIALVLTEVQGEFGLTTVQAASLISAAFISRWFGGLMLGAMGDRYGRRLAMVTSIVLFSAGTLACGFAPGYITMFIARLVIGMGMAGEYGSSATYVIESWPKHLRNKASGFLISGFSVGAVVAAQVYSLVVPVWGWRALFFIGILPIIFALWLRKNIPEAEDWKEKHGGKAPVRTMVDILYRGEHRIANIVMTLAAATALWFCFAGNLQNAAIVAVLGLLCAAIFISFMVQSTGKRWPTGVMLMVVVLFAFLYSWPIQALLPTYLKTDLAYDPHTVANVLFFSGFGAAVGCCVGGFLGDWLGTRKAYVCSLLASQLLIIPVFAIGGANVWVLGLLLFFQQMLGQGIAGILPKLIGGYFDTDQRAAGLGFTYNVGALGGALAPIIGALIAQRLDLGTALASLSFSLTFVVILLIGLDMPSRVQRWLRPEALRTHDAIDGKPFSGAVPFGSAKNDLVKTKS
What is the function of this protein?
Catalyzes the proton-dependent transport of sialic acid.
What are the official names of this protein?
Sialic acid transporter NanT, Sialic acid permease, Sialic acid/H(+) symporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sialate:H(+) symporter (SHS) (TC 2.A.1.12) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HPUB_NEIMA
Sequence: MPIPFKPVLAAAAIAQAFPAFAADPAPQSAQTLNEITVTGTHKTQKLGEEKIRRKTLDKLLVNDEHDLVRYDPGISVVEGGRAGSNGFTIRGVDKDRVAINVDGLAQAESRSSEAFQELFGAYGNFNANRNTSEPENFSEVTITKGADSLKSGSGALGGAVNYQTKSASDYVSEDKPYHLGIKGGSVGKNSQKFSSITAAGRLFGLDALLVYTRRFGKETKNRSTEGDIEIKNDGYVYNPTDTGGPSKYLTYVATGVARSQPDPQEWVNKSTLFKLGYNFNDQNRIGWIFEDSRTDRFTNELSNLWTGTTTSAATGDYRHRQDVSYRRRSGVEYKNELEHGPWDSLKLRYDKQRIDMNTWTWDIPKNYDKRGINGEVYHSFRHIRQNTAQWTADFEKQLDFSKAVWAAQYGLGGGKGDNANSDYSYFAKLYDPKILASNQAKITMLIENRSKYKFAYWNNAFHLGGNDRFRLNAGIRYDKNSSSAKDDPKYTTAIRGQIPHLGSERAHAGFSYGTGFDWRFTKHLHLLAKYSTGFRAPTSDETWLLFPHPDFYLKANPNLKAEKAKNWELGLAGSGKAGNFKLSGFKTKYRDFIELTYMGVSSDDKNNPRYAPLSDGTALVSSPVWQNQNRSAAWVKGIEFNGTWNLDSIGLPKGLHTGLNVSYIKGKATQNNGKETPINALSPWTAVYSLGYDAPSKRWGINAYATRTAAKKPSDTVHSNDDLNNPWPYAKHSKAYTLFDLSAYLNIGKQVTLRAAAYNITNKQYYTWESLRSIREFGTVNRVDNKTHAGIQRFTSPGRSYNFTIEAKF
What is the function of this protein?
Acts as a receptor for hemoglobin or the hemoglobin/haptoglobin complex and is required for heme uptake.
What are the official names of this protein?
Hemoglobin-haptoglobin utilization protein B.
What is the protein family that this protein belongs to?
Belongs to the TonB-dependent receptor family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein.
Protein: YL491_MIMIV
Sequence: MSRTSSQNQEIINNKHRLKTSKSSKPSKSSKPSKSSKPSKSSKTSKSSRSSGSKSSRSKTGKTSSRKDKYKEEYSQDQYPDEQEYEQEYEQEYEQEYQDNGEQTEEFVENNQDAYPEDIENDERQTQSNKELDTINKKTKERLKNKINKWMDHDDNIKRLNAKMKAFKDAKKQEEESIIKLIDKFEIGESKMDIRDDNKNLRGRVYKHKSVTKGAIKEDIIRDALMEVVRNERKVAELVKKIESKRPINERYYLKRTKGNN
What are the official names of this protein?
Uncharacterized protein L491.
Protein: TPIS_CHLTB
Sequence: MFTDKETHRKPFPTWAHLLHSEPSKQFVFGNWKMNKTLTEAQTFLKSFLSSDILSNPQIITGIIPPFTLLSACQQAVSDSPIFLGAQTTHEADSGAFTGEISAPMLKDIGVDFVLIGHSERRHIFHEQNPVLAEKAAAAIHSGMIPVLCIGETLEEQESGATQDILLNQLTIGLSKLPEQASFILAYEPVWAIGTGKVAHPDLVQETHAFCRKTIASLFSKDIAERTPILYGGSVKADNARSLSLCPDVNGLLVGGASLSSENFLSIIQQIDIP
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUD_XANAC
Sequence: MTPFTRHTGLVAPLDRANVDTDQIIPKQFLKSIKRTGFGPNLFDEWRYLDIGEPGRDNSTRPLNPEFVLNFPRYQGASVLLARENFGCGSSREHAPWALDEYGFRTVIAPSFADIFYNNSFKNGLLPIVLAEAQVDALFEQCLTTEGYQLTVDLAAQRVRRPDGVEYGFDIDAFRKHCLLNGLDDIGLTLQDADAIGRFEQGHRARQPWLFGALQ
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: SEY1_KLULA
Sequence: MSDLKEAIQLIDENKQFNPSTLNYFTKCLGDKNVGVKYHVISVFGSQSSGKSTLLNKLFDTKFDTMDAQVKRQQTTRGIWLSHSANIYSSGAANQSIPDFFVLDVEGSDGAERGEDQDFERKAALFALSVSEVLIVNMWENQVGLYQGNNMGLLKTVFEVNLSLFGKNENRHKVALLFVIRDFTGQTPLESLEASLVLELEKMWSQLSKPEGCEDTSFHDFFVPNFFGLGHKVFQPEQFDNDVKSLGDLFVDQDASFFKDEYHTHLPLDGWSLYAENCWEQIENNKDLDLPTQQILVARFKTDEIAAAAYNKFLNDYQSQVTDSLDGKELATVLKTLQSTCIDVDYDPFASRYAKKVYEERRDDLIKQLNTIIDETITNFVTRTTSSLIETFHKNARDRSLKGPFKLKIQSALEKASRTFKTNLAPFSELELLSSMDAYISKFEARVNTEVADLQERELNAIVARFNKGLTIKLKDTILHLLAKPTINVWDDVMKEFTSFLDGSLKKYTNEDGKIDFQTGATTDANDKTEHTLKRNAWSFLDHTVHGYLTEDNVVDIMRNVFNDKFRYDDDGMPKFWKNEAEVDASYRLAKSQALSVLDALAIVKNKDNVEILIPEALLESDGDGSDYEENGGQEEEEAGLYHQQRFSHVLSALQKDKIITKFKQFTDLVIIEAKRSIVNTTERIPLYMYALVVALGWGRIITILRNPATIILSIIVLAGAYFVHKLNLWGPLLQFANQATGQATAVLKQTVRSLVVDEEPKRKILVEPHESEGVDKEPSKNDQHL
What is the function of this protein?
Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network.  Has GTPase activity, which is required for its function in ER organization.
What are the official names of this protein?
Protein SEY1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Enriched in the cortical ER. Concentrated in punctae along the ER tubules.
Protein: ENO_HAEIG
Sequence: MAKIVKVIGREIIDSRGNPTVEAEVHLEGGFVGLAAAPSGASTGSREALELRDGDKSRFLGKGVLKAVAAVNNEIAQAIVGKDATNQAEIDQIMIDLDGTENKSNFGANAILAVSLANAKAAAASKGLPLYAYIAELNGTAGVYSMPLPMMNIINGGEHADNNVDIQEFMIQPVGAKTLREALRIGAEVFHNLAKVLKAKGMSTAVGDEGGFAPNLASNADALACIKEAVEKAGYVLGKDVTLAMDCASSEFYNKENGMYEMKGEGKSFTSQEFTHYLEELCKEYPIVSIEDGQDESDWEGFAYQTKVLGDRVQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRIAKYNQLIRIEEALERAGTPAAFPGLKAVKGQA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: Y2120_YERPY
Sequence: MLCAIYRSPKRDQTYLYIEKKDDFSRVPAELLASFGKPQFAMLLALNERKTLATADVEKVKNALIEQGFYLQVPPPPESLLKMHLGETKA
What are the official names of this protein?
YcgL domain-containing protein YPK_2120.
Protein: YAII_ECO8A
Sequence: MTIWVDADACPNVIKEILYRAAERMQMPLVLVANQSLRVPPSRFIRTLRVAAGFDVADNEIVRQCEAGDLVITADIPLAAEAIEKGAAALNPRGERYTPATIRERLTMRDFMDTLRASGIQTGGPDSLSQRDRQAFAAELEKWWLEVQRSRG
What are the official names of this protein?
UPF0178 protein YaiI.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: PAD1_CAEBR
Sequence: MASASGGDVPAGREKDSKYRAFAKAVDQALKTFETPNEWADLISALGKLAKVFQSNAKYCAIPNRVTVAKRLSQCLHPALPMGVHLKALETYKIIFEILGPSKLPECLYLFAVGLFPLMDHCGIKVKSELFAIFENYLVPLGANLRPALPGFLGGVLLALEEGTEFYERSFILLDRVCEKVGPRAFYACLWQAILGSPPVRLPAMIYVNAKFDKLKSLDDQIHLVGDHVNHMVAALCAVADDTGSPLVQRYLLDFLCAAFPLDSTNLTDEDFVQLLRRCLFVVLRRDMSLNRRLYTWLINRSGETRGVSGLGGPDDGLELSFFKEKVLGLVHGALEQYLALDIIETPFANPQQSIWGDRKEAEQVQFAEVRVCRLLLYLQDRADIGRTILETVFSDFLKKSAEFHQGSNIKLIKKRPDSKPPRKPGDREGLHLDLNSLHSGVSGNSEDVTAPEGEPSIQSRRVDELSKTFNMLLNSLEPGFLWNFLGTWYQRIVEEGSEGKKSIHDFSQVVSICLEMSNVESDPAIRTQHLPRLLETILEGLSNKSLISECDQQDLLKLYTVCQKLLEISTAHPQSPIEVDEIAEDSLSLSQEVTAIEHERSQTDACLTQCVSALSTIFEIYTTRRDPSLIPLIDASTALLNAFLEVPIYYLGFDVVDNPEDVPSEVQQWLKNMLKVIDGPGWLKEMRNGHCSDVSARASLLELLCKIYVKSVSVLQQHEEAAHRPQDDFYDEMTHVLLKPLLGRRDIQFIEQGKVFGTCGEAVWLGIASRKFCCEQQRLARLLVELHSRRPQEASSDVESIVVQALTSTDDLVCTKAARTFHRVWVLTRNLEEAGGIYRKPFNRAVMILLGVLADESVSKTRTELKAAASAWFQDCSKHQDLPKIVQMLSTMLMNPVTARISIQYIRQDSKLTNEDCSAIPSDVAAVTLMTIDGKQRLYHVTGSGADSDASYLTEVRNRLLRASAGEETSEALQAHIIPSTEVLPAFDDDTDSLDTLSMGNESPEDVVKDILAILVDEVCQEYEERERLHDLLNLSNLEASGARFNLNEHEEQEESPEDRPAPIAAVQRVKKGHRRQDSLQESIFNMTEKDLCAFDTSEIFRPSTESLRGTATTSSTRETILPTGTVVGTVSSASSTGGSTSGSSLFEEMHTHMLLYGESGKVVDLARAETAFRILTALLAPRGATGNRMLLNCLVSSGTTTSSGTSSEGGSAEQSLVELMQRHVRAILGQHFWSAPASDEEKHKHFTLLELLITISLHFLRSYFLNSPISPVTEADLASLWKCKISALEFLCELFRELSAMLNEHESKQFVQFVQTILNRSKLQKCLLHLLLTAVDHNPMENGKLGGPLSVSISKFNEGLVGESRRLLPLLAAYHRSLLTFTSHAIRLECDIKRGFSTFSDAQSTHRYSIIQSVINQSFNNRTSSRDGHASTVELRAFLLILLNALKKQPHRHEMWLQFVVQILPWVERSLATIVCRVVEQLCKNMENAMSVAYENPPTSDVVVDSPGETRDEPDSYPANYLAMTLESLTTLVHFCVIDSAPTTTTTSGGVMTSSGAAQINDGTTPSSTSMVGHAMSVIPGSKVATELFSQLGKVFSMSGDSGGVLSSKMESSRQHGNGWRQAQSDMLTSLPHSLATVCNVWTVVRRAQNPLVPIGTNNQLRRLVLHLLSPIAQHHKHAFLTSLALVWLTRSTAKPTVTLRKQDPDRATFEYSSAQLDITNLLLSLQVIPFEDLISSVNSTLREASFKANKVGITTIDKTNFPTEEPLLELVHSCVSAVLQTQLRLCWSSLLSLFSEAPLSALSARAVFLLFVILSDFVKCVGGAYIVEDKAMYRNVQEVCSRLAEAVNAIVGWQLETTTWLKRTLVVKQDHGTSSINSNSIRSVEQSPIIEMQSSISNLSSEASQSTRNSTLSLINKPGGSITSGSTSTTTEKAEKKSSSNLRASIKDTNNNRRDPAHSTQALFLLAERLTDLLDSVSKSDEKDKVLPTLQAVWANVVPYLKAKNARNARFFLASSQLLASMSSYSYMRPVWKKTTLDLLLDSGFFKMDHAALKQWLVVTDHLMTHDRTSFKDLLKSISYSPNASFSIMTSKEQEYEARAQALKRLTFVVFGSQLDQYNGQMNDIQERLSDNLRVSQSPVIRSSFFLCVRVLLLRLRPHSLIGVWPIMVTELVHALSQLEQQLQNNGEQEGSSTSDQWMQLYVAACKLLETLCTLPAGYLSHFQMFHWAFVSSVSADKTEIFKPFAERINDLLAKKYGEFDAMSNHTASLAAVKILTSFEELRPFFYTLANLNKSVPESNNTPLRDAHALSGSLTYKNAVARLESALYVDFSEHLQF
What is the function of this protein?
Essential for cell patterning during gastrulation.  May be involved in protein traffic between late Golgi and early endosomes (By similarity).
What are the official names of this protein?
Protein pad-1, Patterning defective protein 1.
What is the protein family that this protein belongs to?
Belongs to the dopey family.
Protein: KRT82_HUMAN
Sequence: MSYHSFQPGSRCGSQSFSSYSAVMPRMVTHYAVSKGPCRPGGGRGLRALGCLGSRSLCNVGFGRPRVASRCGGTLPGFGYRLGATCGPSACITPVTINESLLVPLALEIDPTVQRVKRDEKEQIKCLNNRFASFINKVRFLEQKNKLLETKWNFMQQQRCCQTNIEPIFEGYISALRRQLDCVSGDRVRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTAFLMKADLETNAEALVQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEIKAQYDDIASRSKAEAEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETENVKAQRCKLEGAIAEAEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRLCEGIGPVNISVSSSKGAFLYEPCGVSTPVLSTGVLRSNGGCSIVGTGELYVPCEPQGLLSCGSGRKSSMTLGAGGSSPSHKH
What are the official names of this protein?
Keratin, type II cuticular Hb2, Keratin-82, K82, Type II hair keratin Hb2, Type-II keratin Kb22.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: PSBD_PARMW
Sequence: MTIAVGRAPQRGWFDILDDWLKRDRFVFVGWSGILLFPTAYLAIGGWLTGTTFVTSWYTHGIASSYLEGCNFLTAAVSTPADAMGHSLLLLWGPEAQGDFVRWCQLGGLWAFVALHGAFALIGFMLRQFEIARLVGIRPYNAIAFSGPIAVFVSVFLMYPLGQSSWFFAPSFGVAAIFRFLLFLQGFHNWTLNPFHMMGVAGILGGALLCAIHGATVENTLFEDGEQANTFKAFEPTQEEETYSMVTANRFWSQIFGIAFSNKRWLHFFMLFVPVMGLWTSSIGIIGLALNLRAYDFVSQEIRAAEDPEFETFYTKNILLNEGLRAWMAPADQPHENFVFPEEVLPRGNAL
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.  D2 is needed for assembly of a stable PSII complex.
What are the official names of this protein?
Photosystem II D2 protein, PSII D2 protein, Photosystem Q(A) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: CNNM4_CAEEL
Sequence: MELYAAGRYDSEPFKMNEHDIIQLYGEDVQYVKNAFLSSDSTCNNNVYSLEEHELDDDKKNLSGVLVEYKIKISLLQSSDGVKHLFFCTNPKSVDIARMLEIPEGKDKTRVYFMMPLLVLCLGLSATFSGLNLAIMSFSINDLKLIQESDSDKLMKQRAMDVMRLRRNSNFVLVTIIFGNCFCNISITLLMNYFAEFYGFGGFIFVELISTALLLIFTEILPSLIFTKNALAIASRLQYFVIFTMCITSPISYPLAMLLNIILGKENADDSAPLDLDALQIDELEDEEAADGNNFHEMMSVVKKTIKLREKLASDVMTEIDKVGMYSEHQQVTHSFLLDAYEQGHSRLPVYEGETRNKIRGVLNITDMMLLMDDEGRGSDTDLTLGTMLSVLEKRRKHCFVLDTMPVEHFMSELQQGCPMAIVVRYKEVDSEEDGTEIYEVCGIVTLEDCIEEILGEIFDEKDARQE
What is the function of this protein?
Probable metal transporter.  Probably acts redundantly with the other metal transport proteins cnnm-1, cnnm-2, cnnm-3 and cnnm-5 to regulate Mg(2+) homeostasis.
What are the official names of this protein?
Metal transporter cnnm-4, CNNM family homolog 4.
What is the protein family that this protein belongs to?
Belongs to the ACDP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TSAD_GEOMG
Sequence: MLILTIETSCDETAAAVVRDGRTVLSSIVATQVKDHAVYGGVVPEIASRKHLESIPVVIDEALRTASVSLDAIEGVAVTQGPGLAGALLVGTAVAKAIAFARRLPIVGVNHIEGHLSAIFLEREVAFPFVALAVSGGHTHLYRVDGIGRYTTLGQTRDDAAGEAFDKVAKLLGLPYPGGVEIDRLAAEGDPASISFPRPLLHDGSFNFSFSGLKTAVLNHVRKNPVQEDGQQLRDLCASFQRAACDVLVTKTLLAAETEGIGRVVVAGGVACNSALRRDMAREAADRGIELAIPSPSLCSDNAAMLAVPGDFYLSRGISDGLSLDALVNWPLDTIRTRLES
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TNPB_STAAU
Sequence: MNASSKRKIISQSEISKKIAVMNEEMQGFWANNSWDIRKCPHPSAIELSKNPALRNRWVRFERVKNLWLRTELKYFYFYHLNNGIWNAKTVWIRKGTVINKMLDFLDLKYPSITSITEVPIEKAMTEYRTYLTKRGVRITTTNYKITANQEKTPVKANSYYVTNLKQFMEFYENFYFDGEEWDKDVWDRRNLPLPDDKVNPTQYEYTINFKGFRNTYFKQLVKRYCKLRLNVDSFSYVSDIAQRLKEFFNFLDMKFKQVQRVHQLTRVEIEAYLSELNMMGIKPSTITGRISILEGLFSTLLRLEWDDVPSKILIYSEDYPKIPRAKPRFIDEFVLEQLNSHLDKLPEYIATMTMIVQECGMRISELCTLKKGCLLEDKDGDFFLKYYQWKMKKEHIVPISKEVALLIKVREDKVSEEFPDSEYLFPRKDGSPLKQETFRGELNKLAYEQNIVDKSGEIYRFHAHAFRHTVGTRMINNGMPQHIVQKFLGHESPEMTSRYAHIFDETLKNEFTKFQEKLVTNNGDVLDLDEDNEVDDVELQWFKKNINAQVLPNGYCRLPVVAGGCPHANACLDCTHFCTSKQFLPQHEEQLERTEELLAIAKDKQWQRQVETNSRVKERLEQIIGSLTG
What is the function of this protein?
One of three proteins encoded by transposon Tn554 required for its transposition.
What are the official names of this protein?
Transposase B from transposon Tn554.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family.
Protein: DEF_LACDA
Sequence: MILMKDIVRDGDPVLRQVAQKLTFPLSDHYRKLADDMMEYLVNSQDPKIAAKHQLRAGVGLAAPQVGEGVSMAALLVPDDKGEIIFKEVYVNPEIISESVRKTCLSEGEGCLSVDKVIDGYVPRPNKVTVHYWTVDGEEKTIRLKGYPAIVSGHEIDHLNGHLFYDRINKENPFALDEDTIVIY
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: RL24_BACCQ
Sequence: MHVKKGDKVQVITGKDKGKQGVILVAFPKQNRVIVEGVNIVKKHSKPSQLNPQGGIITKEAPIHVSNVMILDPKTGEPTRVGFKVEDGKKVRIAKKSGELLDK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: DAPE_RHIWR
Sequence: MIDPLDLTQRLIACPSVTPADAGAMAVIATALESIGFTVHRFAAGEAPDGPVENLFAIRGQGGPHFAFAGHSDVVPPGDGWTSDPFVPEIRGELLHGRGAVDMKGAIAAFIAAAARLGDHPGTISLIITGDEEGPATFGTVALIDWMKARGLCPDLCLVGEPTSTHRLGDMVKIGRRGSVNMWIENVGTQGHVAYPHLAANPIPALVKALDALAALHLDDGNAWFQPSNLEITTVDVGNAATNVIPAVARARLNIRFNDEHRGADLVELVRRTVAEHAPAATVRAVISGESFITPPGDFSALISAAIMKVTGLTPELSTTGGTSDARFLSKLCPVVEFGLCNATMHKLDEAVAIPDLHALADIYEDIVRTVLAHPGA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: ORN_THIDA
Sequence: MALNPTHLLWLDMEMTGLSPESDRIIELAIVVTDADLNTVAEGPVLVVHQPDAVMDAMDSWNRGTHGKSGLIDRVKASQLSESDAEAQMLEFVKQHVSPRTSPMCGNSICQDRRFMARHMPELEAFFHYRNLDVSTLKELAKRWRPGLCDAFKKSNKHEALADIYESIDELRYYREHFIRAE
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_BURO0
Sequence: MKTSMQRKLDQLSTRLAELNDLLSRENVTADLDQYRKLTREHAELGPVVEQYALWRQSRSDETAAQELLADPSMRDFAEDEIRSAREGMARLETELQKMLLPKDPNDDRNIFLEIRAGTGGDESALFAGDLLRMYLRFAERQRWQVEMMSESASDLGGYKEVIVRIAGQGAYSRLKFESGGHRVQRVPATETQGRIHTSACTVAVMPEADEIGEVEINPADLRIDTFRASGAGGQHINKTDSAVRVTHIPTGIVVECQDDRSQHKNKDRALKVLAARIKDKQYHEQHAKEAATRKSLIGSGDRSERIRTYNFPQGRMTDHRINLTLYRLEAIMDGDLDELIGALVTEHQAELLASLGEAD
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.