PharMolix/UniProtQA huggingface dataset:
Protein: RECA_THEM4
Sequence: MSDNKQKKEVLKKAIGKIEKTFGKGSIMFLGEENAVQNIETISSGSVAIDIASGVGGYPRGRIVEIYGPESSGKTTIALHAIASAQKNGGIAAFVDAEHALDPVYAKNLGVDVENLLIAQPDYGEQALEIVDELVRSNAVDLVVIDSVAALVPRAEIEGSMGDVQVGLQARLMSQALRKLAGNINKSKAVVIFINQTRMKIGVMYGNPETTTGGVALKFYSTMRLEVRSIGKITEGKESIGNQVRIKFVKNKVAPPFKEAIVDVIYGKGIVRENELFNLAVDEGLISRRGSWFSYVDSTGTEHSLGQGKNNSLDYLLNHPELLDEIEEKIREKHGLLKKGEKSEEESLE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLV_HAHCH
Sequence: MTTIVSVRRDGKVAMGGDGQVSLGNTVMKGNARKVRRLYHNKVIAGFAGGTADAFTLFERFEAQLEKHQGNLVRAAVELAKDWRTDRALRRLEALLAVADNKASLIITGNGDVIEPENSLIAIGSGGPYAQAAARALLENTELEASDIVKKSLVIAGDICVFTNQNLTLEEIDGTQTPSTV
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIM11_LACTC
Sequence: MASVQLSSRDISVFSNEYKERRRLQMMRFFGATAFTLISARLAFRGVQSRKYVPNMFQLNHKPPTYSFQGEAVSALAFGTGLATGTFSMLVFGTCWVWDISSLAEFTLKMKKLMGEPVTDQALLENTPMDEDTRKVAEALEDMLKGSRKD
What are the official names of this protein?
Altered inheritance of mitochondria protein 11.
What is the protein family that this protein belongs to?
Belongs to the AIM11 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL20_BEUC1
Sequence: MARVKRAVNAQKKRRTTLERASGYRGQRSRLYRKAKEQVTHSLGYAYRDRRARKGDFRRLWIQRINAAARANGITYNRFIQGLKAAEVEVDRRMLAELAVSDPAAFTTLVELAKGALPEDVNAPAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: OPSD_ZOSOP
Sequence: MNGTEGPFFYIPMVNTTGIVRSPYEYPQYYLVNPAAYACLGAYMFFLILVGFPVNFLTLYVTLEHKKLRTPLNYILLNLAVADLFMVFGGFTTTMYTSMHGYFVLGRLGCNIEGFFATLGGEIALWSLVVLAIERWVVVCKPISNFRFGENHAIMGVAFTWFMASACAVPPLVGWSRYIPEGMQCSCGVDYYTRAEGFNNESFVIYMFIVHFCIPLAVVGFCYGRLLCAVKEAAAAQQESETTQRAEREVSRMVVIMVIGFLVCWLPYASVAWYIFTHQGSEFGPPFMTVPAFFAKSSSIYNPMIYICMNKQFRHCMITTLCCGKNPFEEEEGASTTKTEASSVSSSSVSPA
What is the function of this protein?
Photoreceptor required for image-forming vision at low light intensity.  While most salt water fish species use retinal as chromophore, most freshwater fish use 3-dehydroretinal, or a mixture of retinal and 3-dehydroretinal (By similarity).  Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins.  Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity).
What are the official names of this protein?
Rhodopsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell projection, cilium, photoreceptor outer segment. Note=Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to disk membranes in the rod outer segment (OS) photosensory cilia.
Protein: GLB3_MORMR
Sequence: MPIVDSGSVSPLTAADKTKILAAWDLVYKNYEKNSVDILVKFFTGTPAAQAFFPKFKGLTTADDLKKSSDVRWHAERIINAVNDAVKSMDDTEKMSMKLKELSNKHVKNFNVDRKYFKVLAGVIADTVAPGDASFEKLMSIICILLNSAY
What are the official names of this protein?
Globin-3, Hemoglobin III.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: YR745_MIMIV
Sequence: MFGENMCEYEADDIAEKISIKILKKYMRNKIYDTDNSNKPTNQFFCDLHILNKIIRYKCYRDDYERFVSEFIIHKLKYNFASVGYYVKPIIVTDKFELCFEYVVKCKIANHFVALVNSVILNEDSDKKDDKYYYCLIKKFCLNNEIDLKSDLFYYLSDYYCPKI
What are the official names of this protein?
Uncharacterized protein R745.
Protein: RS14_BORPE
Sequence: MAKLSLINRDIKRAKLADKYAAKRAELKAIIDDQSKTDEERYQARLKLQQLPRNANPTRQRNRCVVTGRPRGVFRKFGLTRHKLREMAMKGEVPGMTKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: DHSL_NOSP7
Sequence: MSKQLGQKIAPTPISNDINVVDLIDQYFTAYNSARLREICQLLSRDVLTEGVTVGVSLSGAMTPAGFGVSALAPLIRNGFIDWMISTGANLYHDMHYGLGFELFAGNPFLDDVKLRQEGTIRIYDIIFGYDVLLETDAFIRKILQGEAFQKRMGTAEFHYLLGKYVREVEKQLGVQHSCLLATAYEYGVPIYTSSPGDSSIGMNVAALALEGSQLVLDPSIDVNETAAIAYNARESGGKSAAVILGGGSPKNFLLQTQPQLHEVLGLEERGHDYFVQFTDARPDTGGLSGATPSEAVSWGKIDPEELPNTIVCYTDSTIALPLVTAYVLNKCQPRPLKRIYDKREAILDKLQKDYLAAKTQPSDQVPAAVAESAQKQTATYPCGRLIPNT
What are the official names of this protein?
Deoxyhypusine synthase-like protein.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine synthase family.
Protein: ACUI_CERS4
Sequence: MRAVLIEKSDDTQSVSVTELAEDQLPEGDVLVDVAYSTLNYKDALAITGKAPVVRRFPMVPGIDFTGTVAQSSHADFKPGDRVILNGWGVGEKHWGGLAERARVRGDWLVPLPAPLDLRQAAMIGTAGYTAMLCVLALERHGVVPGNGEIVVSGAAGGVGSVATTLLAAKGYEVAAVTGRASEAEYLRGLGAASVIDRNELTGKVRPLGQERWAGGIDVAGSTVLANMLSMMKYRGVVAACGLAAGMDLPASVAPFILRGMTLAGVDSVMCPKTDRLAAWARLASDLDPAKLEEMTTELPFSEVIETAPKFLDGTVRGRIVIPVTP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of acrylyl-CoA to propanoyl-CoA.  Is essential for growth with 3-hydroxypropanoate as a sole carbon source.  Restores acrylate resistance when expressed in the E. coli strain K12 acuI deletion.
What are the official names of this protein?
Acrylyl-CoA reductase AcuI, Acryloyl-coenzyme A reductase.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Acrylyl-CoA reductase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UTP25_CANTT
Sequence: MAKQVKRKSSGITKPDGNRKRGRSEMRTVTRTAARKPRDEEQDDDSSDHSEEEAVHQSNGDDYEDTDGENDEDEDSGKAYSALLTLLKTDNKEKKEKPESFSIEEKDQPSEDENEVAGVVSDNENEDENEEDQQISDNEEEEEVKGLASDPFEVHFNLPSDDYLNKEEKLVLKDHEKWPIVDKKTYADLALTSMLQLPPGEQIEPPLLKSTKLKDYAIKKRVLDSYEKAYGLDLTETDSLIANSILNYRDVNYQYKTFTNKNYRRIYVMHALNHIYKTRDRILKNTTKLHVHKESSNDEDLEFRDQGFTRPKVLIMLPTRNSCYEVVEQLIKLSGTDQQENKKKFNDQFYAKAAPPNNKPEDFKDAFKGNNSDFFCIGLKMTRKSLKLYSSFYSSDIILASPIGLSMILENPDKKKRQYDFLSSIEVLIVDKSNQIEMQNWDHVNTVMNYINKVPKEFHDADFSRIRMWSINDQARLLRQTLVFCEYLTPSINNLVSSKSFNLSGKVKFKPIINSEKSMMNSIGLKIKQIFQRFESGSPVQDPDARFKFFINTILPSLLKTSSYEDGIMIFIPSYFDYLRVKNYLKTSTKFDFGSIDEYTSQSKLTRTRQGFASGKIKLILYTERLHYFRRYEISGVKTLIMYGLPSNPLFYKELIRFIGKSVFKEECELDLALVKILFSKWDAVNLEKIVGNERAPILCNSMNELYEFR
What is the function of this protein?
DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 25, U3 snoRNA-associated protein 25, U three protein 25.
What is the protein family that this protein belongs to?
Belongs to the UTP25 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PNP_STAHJ
Sequence: MSQEKKVFKTEWAGRSLTIEIGQLAKQANGAVLVRYGDTVVLSTAVASKEPRDGDFFPLTVNYEEKMYAAGKIPGGFKKREGRPGDEATLTARLIDRPIRPLFPKGYRHDVQIMNTVLSADPDCSPEMAAMIGSSMALSVSDIPFQGPIAGVNVGYVDGKYVINPTVEEKEVSRLDLEVAGHKDAVNMVEAGASEITEKEMLEAIFFGHDEIKRLVAFQEEVVAHIQPVKKEFVPVERDEALVSRVKTLTEEKGLKETVLTFDKQQRDENLDTLKAEIATEFVDEADPENELLIDEVYAILNDLVKEEVRRLIADEKIRPDGRKPDEIRPLESEVGLLPRAHGSGLFTRGQTQALSVLTLGALGDYQLIDGLGPEQEKRFMHHYNFPNFSVGETGPVRAPGRREIGHGALGERALKYIIPDTTEFPYTVRIVSEVLESNGSSSQASICGSTLALMDAGVPIKAPVAGIAMGLVTREDSYTILTDIQGMEDALGDMDFKVAGTKEGITAIQMDIKIDGLTREVIEEALEQARQGRLAIMDHMLQTIDQPRKELSAYAPKVEIMHIKPEKIRDVIGPGGKKINEIIDETGVKLDIEQDGTIFIGAIDQDMINRAREIIEDITREAEVGQVYNAKVKRIEKYGAFVELFAGKDALLHISQISKERINKVEDVLSIGDSIDVKITEIDKQGRVNASHKALDENK
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_SYNP2
Sequence: MAEQDWIIIGQVVAAQGLKGEVRINPSTDFPERFEVPGQRWLQLPNQDPQSVELERGRQIPGKNLFVVKFEHIQDRTQAENIRGAKVLVRAGDRPELEADEYHVSDLIGLEVFDYNTQAKLGIVSDLYTAAQDVLEVTDANQKKHLVPFVKAIVPVVDLVENRLEVDAPPGLFEI
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTC_THET2
Sequence: MGGEALTLPKDLLDFSGYGPKELQALLDLAERLKRERYRGEDLKGKVLALLFEKPSLRTRTTLEVAMVHLGGHAVYLDQKQVGIGEREPVRDVAKNLERFVEGIAARVFRHETVEALARHAKVPVVNALSDRAHPLQALADLLTLKEVFGGLAGLEVAWVGDGNNVLNSLLEVAPLAGLKVRVATPKGYEPDPGLLKRANAFFTHDPKEAALGAHALYTDVWTSMGQEAERAKRLRDFQGFQVNGELLKLLRPEGVFLHCLPAHYGEETTEEAVHGPRSRVFDQAENRLHTAKAVLLTLLK
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline, which is a substrate for argininosuccinate synthetase, the enzyme involved in the final step in arginine biosynthesis.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTC, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIP23_ARATH
Sequence: MGVGGTLEYISELIGNGGSHSYGKRKKKKQFQTVELKVRMDCDGCVLKIKNSLSSLKGVKTVEINKKQQKVTVSGYADASKVLKKAKATGKKAEIWPYVPYNLVAQPYIAQAYDKKAPPGYVRKVDPNVTTGTMAVYYDDPSYTSLFSDDNPNACSIM
What is the function of this protein?
Heavy-metal-binding protein.
What are the official names of this protein?
Heavy metal-associated isoprenylated plant protein 23, AtHIP23.
What is the protein family that this protein belongs to?
Belongs to the HIPP family.
Protein: HFB4C_ORYSJ
Sequence: MERCGSWSDCEAAAAAAQKAVPAPFLTKTYQLVDDPATDHIVSWGDDRVSTFVVWRPPEFARDILPNYFKHNNFSSFVRQLNTYGFRKVVPERWEFANEFFRKGEKQLLTEIHRRKTSSASTASPSPPPFFAPPHFPLFHHPGVAAAQHHHAFVGDDGVVAAHGIGMPFPQPHWREPNLPVATRLLALGGPAPSPSSAEAGGAGRAATAAVLMEENERLRRSNTALLQELAHMRKLYNDIIYFVQNHVRPVAPSPAAAAFLQGLGMQARKKPAAANVLNNSGGSTTSSSSLTIAEEPSPPPQQQHLAGEKSGGEAGNSSAARSSAPTKLFGVHLSAAPCGAGSKRASSPEEHPPTSPATKPRLVLECDDLSLTVAPSSSSQQQLSAASSPTSTS
What is the function of this protein?
Transcriptional regulator that specifically binds DNA of heat shock promoter elements (HSE).
What are the official names of this protein?
Heat stress transcription factor B-4c, Heat stress transcription factor 22, OsHsf-22.
What is the protein family that this protein belongs to?
Belongs to the HSF family. Class B subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TRIM5_CHLPG
Sequence: MASGILVNVKEEVTCPICLELLTEPLSLPCGHSLCQACITANHKESMLYKEEERSCPVCRISYQPENIQPNRHVANIVEKLREVKLSPEEGQKVDHCARHGEKLLLFCQEDSKVICWLCERSQEHRGHHTFLMEEVAQEYHVKLQTALEMLRQKQQEAEKLEADIREEKASWKIQIDYDKTNVSADFEQLREILDWEESNELQNLEKEEEDILKSLTKSETEMVQQTQYMRELISDLEHRLQGSMMELLQGVDGIIKRVENMTLKKPKTFHKNQRRVFRAPDLKGMLDMFRELTDVRRYWVDVTLAPNNISHAVIAEDKRQVSYRNPQIMYQSPGSLFGSLTNFSYCTGVPGSQSITSGKLTNFNYCTGVLGSQSITSGKHYWEVDVSKKSAWILGVCAGFQPDATYNIEQNENYQPKYGYWVIGLQEGDKYSVFQDGSSHTPFAPFIVPLSVIICPDRVGVFVDYEACTVSFFNITNHGFLIYKFSQCSFSKPVFPYLNPRKCTVPMTLCSPSS
What is the function of this protein?
Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses.  Blocks viral replication early in the life cycle, after viral entry but before reverse transcription.  In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates innate immune signaling in response to the retroviral capsid lattice.  Binding to the viral capsid triggers its E3 ubiquitin ligase activity, and in concert with the heterodimeric ubiquitin conjugating enzyme complex UBE2V1-UBE2N (also known as UBC13-UEV1A complex) generates 'Lys-63'-linked polyubiquitin chains, which in turn are catalysts in the autophosphorylation of the MAP3K7/TAK1 complex (includes TAK1, TAB2, and TAB3).  Activation of the MAP3K7/TAK1 complex by autophosphorylation results in the induction and expression of NF-kappa-B and MAPK-responsive inflammatory genes, thereby leading to an innate immune response in the infected cell.  Restricts infection by human immunodeficiency virus type 1 (HIV-1) and N-tropic murine leukemia virus (N-MLV) (PubMed:22291694).  Plays a role in regulating autophagy through activation of autophagy regulator BECN1 by causing its dissociation from its inhibitors BCL2 and TAB2 (By similarity).
What are the official names of this protein?
Tripartite motif-containing protein 5, RING-type E3 ubiquitin transferase TRIM5, TRIM5alpha.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly localizes in cytoplasmic bodies. Localization may be influenced by the coexpression of other TRIM proteins, hence partial nuclear localization is observed in the presence of TRIM22 or TRIM27. In cytoplasmic bodies, colocalizes with proteasomal subunits and SQSTM1.
Protein: RLMI_ERWT9
Sequence: MTVRLILAKGREKSLLRRHPWVFSGAVARLEGKAQPGETIDVCDSQGKWLARAAWSPSSQIRARVWSWQQDESIDIDFFVRRLNAAQQLRDWLALRDNLDSYRLIAGESDGLPGITIDRFGNFLVLQLLSAGAEYQRAALITALQRCYPDCAIYDRSDVSVRKKEGLELTQGVVLGDAPPPLLPITEHGMKLLVDIQTGHKTGYYLDQRDSRQATRRYAQGRRVLNCFSYTGGFAVSALMGNCKEVISVDTSQAALDVARQNVELNGLDVSKAHFQRDDVFKLLRRYRDEGEKFDLIIMDPPKFVENKNQLMGACRGYKDINMLAMQLLNPGGMLMTFSCSGLMATDLFQKILADAAVDAQREVQFIEQFRQAADHPVISSYPEGMYLKGFACRVI
What is the function of this protein?
Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase I, 23S rRNA m5C1962 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RlmI.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_METS5
Sequence: MAKKSIKVVVEGGNVKPGPPLAPTLSQLGLNVGEVVKKINEATSQFKGMTVPVTLDVDTDTKKYEVSVGVPTTTSLLVKKAGASGPSGDPEHKKIGNISMDDVIEVAISKKPSLTAKELKGAVKSILGTAKSIGLTVDNKDPKLVVREVEEGKYDDKIKEMEEKWSSG
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: Y2515_STAA3
Sequence: MRKDAKENRQRIEEIAHKLFDEEGVENISMNRIAKELGIGMGTLYRHFKDKSDLCYYVIQRDLDIFITHFKQIKDDYHSNYEVMQVSLDYLLQFKIDNKALLQCIEAGNNKLRFYQSAFYQELFDFYYDLFKSDDDTYTKFKTDMLLQSLSTSVFAFQIEHRHISIEAYRNYLLNIYLDEVGRND
What are the official names of this protein?
HTH-type transcriptional regulator SAUSA300_2515.
Protein: IDI2_RHILO
Sequence: MSDSDNIPSRRKDDHLDIVLDRRTAPATVAAGWEYIRFEHCALPELDLTQIDLRASLLGKTMRAPLLISSMTGGVLRAEAINRHLSEAAQALGIAMCVGSQRVSLQSRNSQGLTRALRRMAPDIPLLANIGAAQLREADGLDLACRAVDALEADGLIVHLNALQEAVQPEGDRDWRGVLAQIARAARSVDVPIVAKEVGSGLSASVACALVKAGVAVIDVAGAGGTSWAAVEGERARDAADRAVAMAFADWGIPTPASVQAVRRALPTVKLIASGGIRDGVDVAKAIRLGADIAGQAAGVLRAATVSTEAVVAHFEIVIRQLAVACFCTGSADLAALRQARLLPSAHLPAG
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SARAF_XENLA
Sequence: MTNMWTLLLLPFFAMLQVHYAWCWSPQDRVLLRDIQTITLYADRYTNARRSAPVPQLKCIGGNAGCHAMVPQVVQCHNRGWDGLDVQWECRVDMDNSYRFGKVEVSCEGFDFPEDPYVLRGSCGLEYTLELTEEGRKRTQDGYRSAGFGSGYFQSNSQSWDSKTDGSSAIVLIFIVILAYGVYKLFLSGPSVQQHPRPDEYGYDHQSQTHSSAPPPGFKSDFTGFSSGYGTGHVNQGPGFWTGLGTGGVLGYLFGNRRAQPYQSPYFNTWTGPSHSESMHQNDRPPQSSGVRTASGFGGTKRR
What is the function of this protein?
Negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+) overfilling.  In response to cytosolic Ca(2+) elevation after endoplasmic reticulum Ca(2+) refilling, promotes a slow inactivation of STIM (stim1 or stim2)-dependent SOCE activity (By similarity).
What are the official names of this protein?
Store-operated calcium entry-associated regulatory factor, SARAF, SOCE-associated regulatory factor, Transmembrane protein 66.
What is the protein family that this protein belongs to?
Belongs to the SARAF family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=Translocates to the endoplasmic reticulum-plasma membrane (ER-PM) region in a STIM1- dependent manner following cytosolic Ca(2+) elevation.
Protein: RL16_MYCAP
Sequence: MLQPKRTKYRKPFLVRHDKRKAHKGNTVEFGEFGLQAVTSAWVDARQIEAARIAITRRMGREGNVIIRIFPHFSKTSKPIGVRMGSGKGSPEKWYTAVKVNTVMFEVSGVSEEIARDALRLGGHKLPVSWKIITKSEGDNQ
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: PURA_TRYB2
Sequence: MAAAPSATAPKHNYTLGTNASQLELYKYLKTVPPIPELRQAVTIKKYEEASVDDTLYPLIDEHQIIMVVGAFFGDEGKGKTVDAVARHPACTCVARVNSGENAGHTVFDDIGRKYVFNLAPSSLLTPNTRNYVSSECVMDPISFMEREIGQFIKSNMPYKDKLFVGNVFVVTPYHKLLDLLGSAPNSSTLKGMSPIHASKVTKRGIRLDHIFNDEGVLRARLAKDMDTYYGLLKVKGLTDKDVVRRCQEENADGVERVPGYVVDFARAENKIDYLVKLYTERVKNNKDFPRRCDVTHELRAALARGEKLLLEGPQSYWLSNAREKFWESTTSADTTAGGLLASAQFNFQRYKVLVINVHKAPGSSRVGIGANPSSFVPQDYYSAQDIKTLEALPKGGCVDFDKIQNFFYTKAFNTESKTFNGIYEPLEYEDATGKYNIGVAMSIASARHHGECGAVTKKPRVCGFFDCVLHFEVNAVQGPYLSISAVDRGDDYDRIGITIAYVYYDVGNKMVDANGRVYKNGDIIKAGDPVPCEMALYHCYPIVKVINGWKGAPIAASKRRPNEPLPKGVCEFIANVEFFTGAKVISIGNGPRGSDIIYLKQ
What is the function of this protein?
Plays an important role in the salvage pathway for purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APEB_AZOVD
Sequence: MRTELNQGLIDFLKASPTPFHACASLAQRLESAGYQRLDEREPWPTQSGGRYYVTRNDSSLIAIQLGRRSPLEGGLRLVGAHTDSPCLRVKPQPELNRQGFWQLGVEVYGGALLAPWFDRDLSLAGRVTFRRAGRVESQLIDFKQPIAVIPNLAIHLNREANQGWAINAQNELPPILAQVAGDERGDFRALLAEQLQREHEINADVVLDFELCFYDTQSAALIGLNQDFIAGARLDNLLSCHAGLQALLAAGDRESCVLVCTDHEEIGSCSTCGADGPFLEQVLGRLLPDGDAFVRIMQQSLLVSADNAHGVHPNYADRHDANHGPKLNAGPVIKVNSNQRYATNSETAGFFRHLCFDVEVPVQSFVVRSDMGCGSTIGPITASRLGMRTVDIGLPTFAMHSIRELAGSHDLTHLVKVLTAFYSSPLLP
What are the official names of this protein?
Probable M18 family aminopeptidase 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M18 family.
Protein: RS3_STRP2
Sequence: MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQKELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINIIEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGADIARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: TMCAL_HALOH
Sequence: MPVLGIITEYNPFHNGHLYHLNQARTITDSNAVICIMNGNFVQRGEPALIDKWARTRMALKNGVDLIIELPLIYGIRSAEYFAYGAVTLLEETKTVDYLVFGSESGNTDILKVVARILYEEPHNFKQYLKKYISQGLSFPRAREKALLKYVQQTDNIPYSVNEIADVIKQPNNILGIEYIKALFRINSTIKPVAIRRKGKGYHSHSLETKITSATAIRKGIYEQGLNSVKQAITPVTYKILKEEFENGKGPVQKQLLQHAILAELRKLTPEKIRQYEGVKNGLEYRFLEAAHNSGTLTGLIENIKNKNLTWTRIQRTLLHILFNIREKDFRILDKKGPRYFRVLGFNKKGEKLLSKIKQNSRLPLITHLKPHLKQVNRNSLNLLEKSLSYDVLSSDMYSLLYPDPSKRRGRKDFLIPVIKNI
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPDS1_ORYSJ
Sequence: MEAEAAAKRARESGDAAAAGAGEQAGISAVIPGWFSEISPMWPGEAHSLKVEKVLFQGKSDYQNVMVFQSSTYGKVLVLDGVIQVTERDECAYQEMITHLPLCSIKDPKKVLVIGGGDGGVLREVSRHSSVEQIDICEIDKMVVDVSKQFFPHLAVGFEDPRVSLHIGDGVAFLKNAPEGTYDAVIVDSSDPIGPAQELFEKPFFQSVARALRPGGVVCTQAESIWLHMHIIEDIVANCRQVFKGSVNYAWTTVPTYPSGVIGFMLCSTEGPTVDFQHPIFNIEDNEFSTKSKGPLKFYNSEIHSASFCLPSFAKRVIGSKAN
What are the official names of this protein?
Spermidine synthase 1, SPDSY 1, Putrescine aminopropyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
Protein: ALR_XANC5
Sequence: MRPAQASIDLEALRHNYRLARRLGGSKALAVVKADAYGHGAVRCAQALEPEADGFAVACIEEALELRQAGIRAPILLLEGFFEHDELRLIAEHDLWTVAATQQQVRALAEFQSPRPLRVWLKMDSGMHRLGLSPEDFRAAWLRLRGLPQIASLVLMTHLARADELDCSRTDEQAVAFALTAGGMRAETSLRNSPGLLGWPALRNDWSRPGLMLYGANPFPQHTENTAQLRPVMTLRSRIISVRELPAGEPVGYGARFVAERPTRVGVVAMGYADGYPQFAPNGTPVLVDGQICPLIGRVSMDMLTVDLTDHPQADIGTPVQLWGDAPQVSALAAQCNVSAYQLLCGLKRVPRIYVGEAAVGKLSA
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: SMCR5_HUMAN
Sequence: MRRCLRVKTRRGQLGLASSCFEQHSCFSPRVNRILSAVQNTLCTGPSSQAPPQPPQASPPAAADHSRTPSLLASSHSASGGESLFQLYIASLAWPQNCCVLESCRRIPLGGLSSMENRRPLLRKGRLLRGQIHHSQTNEL
What are the official names of this protein?
Smith-Magenis syndrome chromosomal region candidate gene 5 protein.