PharMolix/UniProtQA huggingface dataset:
Protein: RS17_ANOGA
Sequence: MGRVRTKTIKKASKVIIEKYYTRLTMDFDTNKRIVEEVAIIPTKPLRNKIAGFVTHLMKRLRHSQVRGISIKLQEEERERRDNYVPDVSALEQDIIEVDPETKEMLKHLDFNNIVVQLTNPTAPGYSNRRN
What are the official names of this protein?
40S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS17 family.
Protein: GYAR_THEGJ
Sequence: MKPKVFITRAIPENGIDMLREHFEVEVWPEEREIPREVLLEKVRDVDALVTMLSERIDGEVFDNAPRLRIVANYAVGYDNVDVEEATRRGIYVTNTPDVLTNATADFAWTLLLATARRLIEADSFTRSGEWKRKGIAWHPLMFLGHDVYGKTIGIIGFGRIGQAVARRAKGFGMRILYYSRTRKPEAEEELKAEFKPLEELLKESDFVVLAVPLTKETYHMIGERELKLMKPTAILVNIARGKVVDTEALIKALKEGWIAGAGLDVFEEEPYYNEELFSLKNVILAPHIGSATFGAREGMAELVARNLIAFKNGEVPPTLVNKEVVKVKKPGFR
What are the official names of this protein?
Glyoxylate reductase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GyaR subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXC_CYACA
Sequence: MYNYTIYHPVKISGRGLYTGINSTITIYPELPHVGIYFLRTDLTDYPIVPIIPSTLLVLNSKLSTVLGFHDDYSIMLIEHLMSAISLSQLTDLKIILEGPEIPILDGSSIIWLKLLQQAKIYITSLSNCIIFKSSCTFFIQTKDTFIISFPYTSLAINTGIDFKNCLAIKSQWITILDLLINRFELVGIASSRTFGDFNQINILINEGFFQGANLYNALAFQLGNWCNGPLRFICEPAKHKVLDLIGDLRLLGVYNMFFLIGYKTNHFVNSQLVQFFKKLDK
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that in bacteria anchors the lipopolysaccharide to the outer membrane of the cell.  The target for the lipopolysaccharides produced in the chloroplast could either be the cell envelope of the eukaryote or the plastid membrane.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MTMRC_HUMAN
Sequence: MLGKGVVGGGGGTKAPKPSFVSYVRPEEIHTNEKEVTEKEVTLHLLPGEQLLCEASTVLKYVQEDSCQHGVYGRLVCTDFKIAFLGDDESALDNDETQFKNKVIGENDITLHCVDQIYGVFDEKKKTLFGQLKKYPEKLIIHCKDLRVFQFCLRYTKEEEVKRIVSGIIHHTQAPKLLKRLFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGYKVCERLPAYFVVPTPLPEENVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGILQIQKSFLDGIYKTIHRPPYEIVKTEDLSSNFLSLQEIQTAYSKFKQLFLIDNSTEFWDTDIKWFSLLESSSWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHCRTRIGFQSLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPPAFEFTETYLTVLSDSLYIPIFSTFFFNSPHQKDTNMGREGQDTQSKPLNLLTVWDWSVQFEPKAQTLLKNPLYVEKPKLDKGQRKGMRFKHQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGKRISKLINSSDELQDNFREFYDSWHSKSTDYHGLLLPHIEGPEIKVWAQRYLRWIPEAQILGGGQVATLSKLLEMMEEVQSLQEKIDERHHSQQAPQAEAPCLLRNSARLSSLFPFALLQRHSSKPVLPTSGWKALGDEDDLAKREDEFVDLGDV
What is the function of this protein?
Acts as an adapter for the myotubularin-related phosphatases (PubMed:11504939, PubMed:12847286, PubMed:23818870).  Regulates phosphatase MTM1 protein stability and possibly its intracellular location (PubMed:23818870).  By stabilizing MTM1 protein levels, required for skeletal muscle maintenance but not for myogenesis (By similarity).
What are the official names of this protein?
Myotubularin-related protein 12, Inactive phosphatidylinositol 3-phosphatase 12, Phosphatidylinositol 3 phosphate 3-phosphatase adapter subunit, 3-PAP, 3-phosphatase adapter protein.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Sarcoplasmic reticulum. Cytoplasm, myofibril, sarcomere. Note=Localizes to punctate vesicles when associated with MTM1 (PubMed:12847286). Localizes to triads, a structure formed by a T tubule and two sarcoplasmic reticulum terminal cisterna (By similarity). In skeletal muscles, co-localizes with MTM1 in the sarcomere (By similarity). Partially localizes to the sarcoplasmic reticulum in skeletal muscles (By similarity).
Protein: UVRC_CYTH3
Sequence: MLEKEDIRSLLKELPSSPGVYRFYSIEKELIYVGKAKSLRKRVANYFTNKKNLDQKTRSMVRKIYHAEYTLVNSEYEALLLENNLIKENKPKYNVLLRDDKTYPFICLSSADFPTLTTTRKIDKKKGEYFGPYTSGRAMHSLVESLRKTFFIRTCDLNLTKQNIDAHKFKVCLEYHIGNCKGPCEGKQEKEDYDVSIIQVRNILKGNFSSVKKYYQEKMLSAAEDMQFEKAQFFKERYNSVLGLEKSSLIVNPDINNLEVYTIVKRLNRASVNFMSILHGSIIKARTIEMKAVLDETEEELLMHALFEIHEEGWDSTKEIICNIELPILSTYCKVSIPQRGDKKKLIDLSLKNAWHTLTRYDDQKKEKPEIRVLKTLQADLSLKELPAHIECFDNSNIQGTNPVAAMVCYKNGKPSKKDYRHFNIKTVEGPNDFASMYEIVYRRYKRMGEEGLPFPTLIIIDGGKGQLSFACQALKDLNIYGQIPIVSIAKNLEELFFPGDNDPLYLDKKSESLKLIQQIRDETHRFAITFHRQKRSKDALLKTEFENLVGIGPGTVKKLLTHFKTVKRIKEASIEQLTPVIGNSKATILFQQLNK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PP400_ARATH
Sequence: MLIRCVAVAKTRFNTTGVVSRLVSSLADGSDTSSVANRNSLKEILRKNGPRRSVTSLLQERIDSGHAVSLSELRLISKRLIRSNRYDLALQMMEWMENQKDIEFSVYDIALRLDLIIKTHGLKQGEEYFEKLLHSSVSMRVAKSAYLPLLRAYVKNKMVKEAEALMEKLNGLGFLVTPHPFNEMMKLYEASGQYEKVVMVVSMMKGNKIPRNVLSYNLWMNACCEVSGVAAVETVYKEMVGDKSVEVGWSSLCTLANVYIKSGFDEKARLVLEDAEKMLNRSNRLGYFFLITLYASLGNKEGVVRLWEVSKSVCGRISCVNYICVLSSLVKTGDLEEAERVFSEWEAQCFNYDVRVSNVLLGAYVRNGEIRKAESLHGCVLERGGTPNYKTWEILMEGWVKCENMEKAIDAMHQVFVLMRRCHWRPSHNIVMAIAEYFEKEEKIEEATAYVRDLHRLGLASLPLYRLLLRMHEHAKRPAYDIYEMMKLDKL
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At5g27460.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
Protein: MTNC_PERMH
Sequence: MIKAVLIDIEGTVSPISFVKEVLFPYSKERIEEFIKKNLDNPDIKRIIQDIKNIEGRDLTLEEVVNTLIRWIDQDKKITPLKEIQGYIWEEGFRSGRLKAPVYEDAYRKLKEWKEKNIPMYIYSSGSVKAQKLFFSHTEYGDLTGFFSGFFDTKTGNKKDPQSYLKIAEAVGLKPENILFLSDNPDEIRAAAEAGMKVIKISRPEDSPYIDNFPYRQVDSFDQITDL
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
Protein: UVRB_STAHJ
Sequence: MVEHYPFKLNSEFDPQGDQPQAIEKIVKGVKEGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLVVSVRVGMEMDRSELLRKLVDVQYSRNDIDFQRGTFRVRGDVVEIFPASREEMCIRVEFFGDEIDRIREVNYLTGEVIREREHFAIFPASHFVTREEKMKIAIERIEKELEERLKELKDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDDWLVMIDESHVTLPQIRGMFNGDRARKQVLVDHGFRLPSAMDNRPLKFEEFEQKTNQLVYVSATPGPYEIEHTDEMIEQIIRPTGLLDPKIDVRPTKNQIDDLLSEIQERIDRDERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVVVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNEKGEVIMYADKITDSMQYALDETQRRRDIQTAHNEKYGITPKTINKKIHDVISATVDNDETNEKQQTELPKKMTKKERQKTIENIEKEMKKAAKDLDFEKATELRDMLFELKSEG
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNM3A_MOUSE
Sequence: MPSSGPGDTSSSSLEREDDRKEGEEQEENRGKEERQEPSATARKVGRPGRKRKHPPVESSDTPKDPAVTTKSQPMAQDSGPSDLLPNGDLEKRSEPQPEEGSPAAGQKGGAPAEGEGTETPPEASRAVENGCCVTKEGRGASAGEGKEQKQTNIESMKMEGSRGRLRGGLGWESSLRQRPMPRLTFQAGDPYYISKRKRDEWLARWKREAEKKAKVIAVMNAVEENQASGESQKVEEASPPAVQQPTDPASPTVATTPEPVGGDAGDKNATKAADDEPEYEDGRGFGIGELVWGKLRGFSWWPGRIVSWWMTGRSRAAEGTRWVMWFGDGKFSVVCVEKLMPLSSFCSAFHQATYNKQPMYRKAIYEVLQVASSRAGKLFPACHDSDESDSGKAVEVQNKQMIEWALGGFQPSGPKGLEPPEEEKNPYKEVYTDMWVEPEAAAYAPPPPAKKPRKSTTEKPKVKEIIDERTRERLVYEVRQKCRNIEDICISCGSLNVTLEHPLFIGGMCQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFFANNHDQEFDPPKVYPPVPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDSITVGMVRHQGKIMYVGDVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGRLFFEFYRLLHDARPKEGDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMIDAKEVSAAHRARYFWGNLPGMNRPLASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQHFPVFMNEKEDILWCTEMERVFGFPVHYTDVSNMSRLARQRLLGRSWSVPVIRHLFAPLKEYFACV
What is the function of this protein?
Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development (PubMed:9662389, PubMed:11399089, PubMed:10555141, PubMed:11919202, PubMed:16567415, PubMed:17713477).  DNA methylation is coordinated with methylation of histones (PubMed:9662389, PubMed:11399089, PubMed:10555141, PubMed:11919202, PubMed:16567415, PubMed:17713477).  It modifies DNA in a non-processive manner and also methylates non-CpG sites (PubMed:9662389, PubMed:11399089, PubMed:10555141, PubMed:11919202, PubMed:16567415, PubMed:17713477).  May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1 (PubMed:18823905).  Plays a role in paternal and maternal imprinting (PubMed:15215868).  Required for methylation of most imprinted loci in germ cells (PubMed:15215868).  Acts as a transcriptional corepressor for ZBTB18 (PubMed:11350943).  Recruited to trimethylated 'Lys-36' of histone H3 (H3K36me3) sites (PubMed:20547484).  Can actively repress transcription through the recruitment of HDAC activity (PubMed:11350943).  Also has weak auto-methylation activity on Cys-706 in absence of DNA (PubMed:21481189).
What are the official names of this protein?
DNA (cytosine-5)-methyltransferase 3A, Dnmt3a, Cysteine methyltransferase DNMT3A, DNA methyltransferase MmuIIIA, DNA MTase MmuIIIA, M.MmuIIIA.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Cytoplasm. Note=Accumulates in the major satellite repeats at pericentric heterochromatin.
Protein: QCRB_STRCO
Sequence: MSTAANEPSRSRGKAPAGERVADWADGRLGIYSLAKANMRKIFPDHWSFMLGEVCLYSFIIIILTGVYLTLFFHPSMAEVEYHGSYVPLQGQMMSEAYASTLDISFDVRGGLLIRQIHHWAALIFLAGMFVHMMRVFFTGAFRKPREVNWLFGFLLLVLGMFTGFTGYSLPDDLLSGTGIRFMEGAILSVPIVGTYISFFLFGGEFPGHDFVSRFYSIHILLLPGIMLGLLVGHLILVFYHKHTQFAGPGKTNKNVVGMPLLPVYTAKAGGFFFLVFGVISVVSAIATINPIWAIGPYRPDQVSTGAQPDWYMGFSEGLIRVMPGWEINAWGHTLVLGVFVPLLIFPLVLAAIAVYPFIESWVTGDKREHHILDRPRNAPTRTAFGVAWLTVYFVLLIGGGNDLWATHFHLSINAITWFVRIAFFVGPVVAFIATKRICLGLQRRDKDKVLHGRESGIIKRLPHGEFIEVHEPLSQEQLHTLTAHEQYQPAEIGPTVDENGVERKVSGTQKLRAKLSESYYGEESQIPKPTVEEYKEITSGHGHH
What is the function of this protein?
Cytochrome b subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis.  The bc1 complex catalyzes the oxidation of ubiquinol and the reduction of cytochrome c in the respiratory chain.  The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.  The cytochrome b subunit contains two ubiquinol reactive sites: the oxidation (QP) site and the reduction (QN) site.
What are the official names of this protein?
Cytochrome bc1 complex cytochrome b subunit, Cytochrome bc1 reductase complex subunit QcrB, Ubiquinol--cytochrome c reductase cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MASZ_BRUA4
Sequence: MVSQKAGNYVEIEGLRVAPELVEFLAKEAAPGTGVEPEKFWKGFAAIIRDLAPKNRALLAKRDDLQAKIDAWYKQNRDKGYSQADYQQFLKNIGYLLPEGGEFSVSTTNVDPEITHIAGPQLVVPVMNARYALNAANARWGSLYDALYGTDAISDADGGEKGKGYNPKRGEKVIAWAKNFLDESAPLATGNWANVAGLAVKDGKLEIKLTDGSATALKDANQFKGYNGDAAAPTNVLLAKNNMHVDIVVNADHPIGKTDPAHIADVVLESAVSTIQDCEDSIAAVDAEDKVAVYRNWLGLMNGKLEDTFEKNGKQMTRRLNGDRSYKAADGSTLSLKGRSLMLVRNVGHLMTNPAIIDADGHEVPEGIMDAAFTSLIALHDIGPNGRHMNSREGSVYIVKPKMHGPEEVAFANEIFTRTEEMLGMKPNTLKIGIMDEERRTTVNLKEAIRAAKERVVFINTGFLDRTGDEIHTSMEAGPMIRKGDMKQAAWIGAYEQWNVDIGLECGLSGHAQIGKGMWAMPDLMAAMLEQKIAHPKAGANTAWVPSPTAATLHATHYHQVDVAAVQAKLKSRPRAKLDDILSVPVATRPNWTPEDIQHEIDNNAQGILGYVVRWVDQGVGCSKVPDINNVGLMEDRATLRISAQHIANWLYHGVVSEAQVMETMKRMAAVVDKQNEGDALYRPMAADFDKSIAFQAACDLVFKGREQPNGYTEPVLHRRRLELKAQG
What is the function of this protein?
Involved in the glycolate utilization.  Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
What are the official names of this protein?
Malate synthase G.
What is the protein family that this protein belongs to?
Belongs to the malate synthase family. GlcB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS5_SHEB2
Sequence: MAKLEAQQKDDLQEKLIAVNRVSKVVKGGRIFSFTALTVVGDGNGKIGYGYGKAREVPAAIQKAMEKARRNIVTVELNAGTLHHPVKGRHTGSLVYMQPASQGTGIIAGGAMRAVLEVAGVHNVLSKAYGSTNPINIVRATVDALVHMKSPSQIAAKRGLNVDEIRG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: RLMM_PHOPR
Sequence: MNHVILYCRPGFEKECAGEVQDKANKLELFGFPRTKNNTGYVVFEFHQQGDADKFIKLQPFSSLIFARQMFAATKLLTDLPQEDRISPILEAVKGFPRCGELRIETPDTNEAKELLKFCRKFTVPLRQAMRKKDVLYAQDSTWKPVLHVCFIAPGCCFVGYSYTNNNSQFFMGIPRLKFPSDAPSRSTLKLEEAFHVFIPRDEWDERLAPGMWGVDLGACPGGWTYQLVKRSMFVHAIDNGQMAQSLMDTGQVKYHAVDGFKFEPARKNVTWIVCDMIEKPARVAHLMGEWLVKAWAKEAIFNLKLPMKGRYDEVLQDIENLKQYFIKNGMKFELQAKHLYHDREEITVHVRCLDNRSPH
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_STRS7
Sequence: MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFQDFLDSGLKEVFEDVLPISNFTDTMELEFVGYEFKEPKYTLEEARIHDASYSAPIFVTFRLINKETGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGSTVIPNRGAWLELETDSKDIAYTRIDRTRKIPFTTLVRALGFSGDDEIIDIFGDSELVRNTIEKDIHKNQSDSRTDEALKEIYERLRPGEPKTADSSRSLLTARFFDARRYDLAAVGRYKINKKLNIKTRLLNQIIAENLIDSETGEILVEAGTEMTRSVIESIEEQLDGDLNKFVYTPNDYAVVTEPVILQKFKVVSPVDPDRVVTIVGNANPDDKVRALTPADILAEMSYFLNLAEGLGKVDDIDHLGNRRIRAVGELLANQFRIGLARMERNVRERMSVQDNDVLTPQQIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVRDVHYTHYGRMCPIETPEGPNIGLINNLSSFGHLNKYGFIQTPYRKVDRVIGRVTNEIVWLTADEEDEFTVAQANSKLNPDGTFAEEIVMGRHQGNNQEFPASQVDFVDVSPKQVVAVATACIPFLENDDSNRALMGANMQRQAVPLIDPKAPYVGTGMEYQAAHDSGAAVIAQHNGKVVFSDAERVEVRREDGSLDVYHITKFRRSNSGTAYNQRTLVKIGDIVEKGDFIADGPSMEKGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKEDVYTSVHLEEFESETRDTKLGPEEITREVPNVGEEALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERLLHAIFGDKSREVRDTSLRVPHGGDGIVRDVKIFTRANGDELQSGVNMLVRVYIAQKRKIKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHLGMAARNLGIHIATPVFDGATSEDLWETVREAGMDSDAKTVLYDGRTGEPFDNRVSVGVMYMIKLHHMVDDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVLQEILTYKSDDVNGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDNEVELRDLDEGEDDDVMHVDDLEKAREKQAQETQEIAESTEDN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: RSXA_ECO57
Sequence: MTDYLLLFVGTVLVNNFVLVKFLGLCPFMGVSKKLETAMGMGLATTFVMTLASICAWLIDTWILIPLNLIYLRTLAFILVIAVVVQFTEMVVRKTSPVLYRLLGIFLPLITTNCAVLGVALLNINLGHNFLQSALYGFSAAVGFSLVMVLFAAIRERLAVADVPAPFRGNAIALITAGLMSLAFMGFSGLVKL
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit A, Rsx electron transport complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MUG35_SCHPO
Sequence: MTNERHDELACLGIFPLKNPKQLDGVVTPILQLRVKFLAPTDRWWEGLVINKDLSKEESEELWKFLQSFDPRSAKFVGRGTPEDHVISYLFEAGKYEFEVFFYQKDHSLKLMGLYDKTQKQLLRRDSSGDLTSTDKERDVSPVSHSEKPYWDRYDLDQPSNQDVEESRNLVQEPKHRSKKYDRLGLDELVMEQTASLWKICSRNGMSVDEFLRFIRMGLESNFQHSNQVIPTHF
What is the function of this protein?
Has a role in meiosis.
What are the official names of this protein?
Meiotically up-regulated gene 35 protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAAA_THEVO
Sequence: MIMKIYVVDNGGQWTHREWRVLRELGVETEIVPNDIESRKLDGLDGLVLSGGAPNIDEEMDKLGSIGEYIEDHDYPVFGICVGAQFIALHYGAQVVKAKHPEFGKTLVKISEPANVLAGLPENIIAWENHNDEIKNLTSDFVLTASSETCEVQAFYHKHKPLYAVQFHPEVEHTQFGREIFKNFIAICQQHKEKLINNVNNK
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing] subunit A, Glutamine amidotransferase.
Protein: PHOU_ENTCL
Sequence: MDNLNLNKHISGQFNAELESIRTQVMTMGGMVEQQLSDAITAMHNQDSELAKRVIEGDKNVNMMEVAIDEACVRIIAKRQPTASDLRLVMAIIKTIAELERIGDVADKICRTALEKFSQQHQPLLVSLESLGRHTVQMLHDVLDAFARMDLDEAVRIYREDKKVDQEYEGIVRQLMTYMMEDSRTIPSVLTALFCARSIERIGDRCQNICEYIFYFVKGQDFRHVGGDELDKLLAGKDPKE
What is the function of this protein?
Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis.  Encoded together with proteins of the phosphate-specific transport (Pst) system in the polycistronic pstSCAB-phoU operon.  PhoU is essential for the repression of the Pho regulon at high phosphate conditions.  In this role, it may bind, possibly as a chaperone, to PhoR, PhoB or a PhoR-PhoB complex to promote dephosphorylation of phospho-PhoB, or inhibit formation of the PhoR-PhoB transitory complex (By similarity).
What are the official names of this protein?
Phosphate-specific transport system accessory protein PhoU, Pst system accessory protein PhoU.
What is the protein family that this protein belongs to?
Belongs to the PhoU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_NEOSM
Sequence: MKRTLSILKPDVISRNITGKVNAYIEAAGLQIIAMKQLHLTRIQAEAFYVVHKDRFFFNDLVNFMTSAPVIVQVLSGDDAVHRYRKLMGDTDPKKAAKGTIRGDFAESIDANCVHGSDSEENAKNEIAFFFSRCEIFDR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y506_MYCBO
Sequence: MWRPAQGARWHVPAVLGYGGIPRRASWSNVESVANSRRRPVHPGQEVELDFAREWVEFYDPDNPEHLIAADLTWLLSRWACVFGTPACQGTVAGRPNDGCCSHGAFLSDDDDRTRLADAVHKLTDDDWQFRAKGLRRKGYLELDEHDGQPQHRTRKHKGACIFLNRPGFAGGAGCALHSKALKLGVPPLTMKPDVCWQLPIRRSQEWVTRPDGTEILKTTLTEYDRRGWGSGGADLHWYCTGDPAAHVGTKQVWQSLADELTELLGEKAYGELAAMCKRRSQLGLIAVHPATRAAQ
What are the official names of this protein?
Uncharacterized protein Mb0506c.
What is the protein family that this protein belongs to?
To M.leprae ML2435 and S.coelicolor SCO3349.
Protein: CYB_LAECA
Sequence: MTNIRKSHPLIKIVNSSFIDLPTPSSISSWWNFGSLLGICLALQILTGLFLAMHYTSDTSTAFNSVAHICRDVNYGWMLRYLHANGASMFFICLYLHVGRGLYYGSYMFKETWNMGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFLLPFIIAALVMVHLLFLHETGSNNPTGIPSDMDMIPFHPYHTIKDILGLFMMILALLSLVLFTPDLLGDPDNYSPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSILILIIIPLLHTSKQRSMIFRPLSQCSFWLLTADLLALTWIGGQPVEHPYIIIGQLASILYFLIIIVIMPLAGLMENHLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RUTE_KLEP7
Sequence: MNDAINHTACETLFTQARTHNGWLDKPVSDAQLQAVWDLMKMGPTSANCSPARIVFVRSAEGKEKLRPTLSSGNLQKTMQAPVTAIVAWDSAFYDRLPTLFPHGDARSWFTSSPQLAEETAFRNSSLQAAYLIFACRARGLDTGPMSGFDREKVDAAFFADNGWKSNLLVNIGYGDPGKLYGRLPRLSFDEACLLA
What is the function of this protein?
May reduce toxic product malonic semialdehyde to 3-hydroxypropionic acid, which is excreted.
What are the official names of this protein?
Probable malonic semialdehyde reductase RutE.
What is the protein family that this protein belongs to?
Belongs to the nitroreductase family. HadB/RutE subfamily.