PharMolix/UniProtQA huggingface dataset:
Protein: RL31_CALS4
Sequence: MKPGIHPTYYHDAVVKCACGNTFITGSTKKEIRVEICSKCHPFFTGQQKIVDTGGRVERFRKRFNLEEK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: RL10_GEOMG
Sequence: MNRENKQQQVAELHEKLKRAKAVFLADFRGMSVEQATTLRNELRAAAVEYKVAKNTLLELASKETDKESLSPHYAGPTAIAFSYDDPVAAAKVLSKFAKTQANTFKLKAAVLSGKQISVSDIQALADLPSREVLLAKLLGTINAPVANFVGVLAAVPGSFVRALNAIKIQKEGN
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: RS12_XANOR
Sequence: MTTINQLVRKPRQATTYKSASPALDKCPQRRGVCTRVYTTTPKKPNSALRKVAKVRLTNQEEVISYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHTVRGSLDAAGVAKRRQGRSKYGAKRPKS
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: HIS51_CAMJR
Sequence: MIALIDYKAGNLNSVAKAFEKIGAINFIAKNPKDLQKADKLLLPGVGSFKEAMKNLKELGFIEALKEQVLVQKKPILGICLGMQLFLERGYEGGVCEGLGFIEGEVVKFEEDLNLKIPHMGWNELEILKQVPLYQGIDNKSDFYFVHSFYVKCKDEFVSAKAQYGHKFVASLQKDHIFATQFHPEKSQNLGLKLLENFIRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH 1, IGP synthase glutaminase subunit 1, IGP synthase subunit HisH 1, ImGP synthase subunit HisH 1, IGPS subunit HisH 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LHX9_PSAFA
Sequence: MLFHGIPGEHIQGIMEEMERRSKSESRLAKTVQMNGRETSMPSVSPEKPALCAGCGSKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDSVYHLSCFTCTSCNKTLTTGDHFGMRENLVYCRAHFESLVQGEYHAPLNYAELAAKGGGLALPYFNGASAVQKGRPRKRKSPAMGIDINTYNSGCNENDADHLDRDQQPYPPSQKTKXMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNVLRQENGGVDKADGTSLPPPSSDSGALTPPSTATTLTDLTNPSITVVTSVTSSLDSHDSGSPPQTTLTNLF
What is the function of this protein?
May be involved in gonadal development.
What are the official names of this protein?
LIM/homeobox protein Lhx9, LIM homeobox protein 9.
Protein: NIFV1_NOSS1
Sequence: MNKVLINDTTLRDGEQAAGVVFTLEEKVAIAKFLDTIGVPELEVGIPAMGEEEMRAICAISNLGLKANLLAWNRAVISDIKASVACGMERVHIAIPVSGIQIAAKFHGQWRVSLQRLKDCISFAVDQGLWVAVGGEDSSRADENFLLDVALYAQEWGASRFRFCDTVGVLDPFTTYGKVKLLVSALTIPVEVHTHNDFGMATANALAGIKAGASSVNTTVIGLGERAGNAALEEVVMAIKRIYGVDMGIDTPRLLELSQLVAAASGANVPPWKAIVGENTFAHESGIHAHGVLQNPDTYEPFAPEEVGWERRLVVGKHSGRHSVSNLLEQHGIFLNPEETQSVLDAVRQQSIKKKRSLTTEELLNLVKEQRYSHAAR
What is the function of this protein?
This protein is a Fe-Mo-cofactor biosynthetic component.
What are the official names of this protein?
Homocitrate synthase 1.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family.
Protein: GSPH_VIBCH
Sequence: MTATRGFTLLEILLVLVLVSASAVAVIATFPVSVKDEAKISAQSFYQRLLLLNEEAILSGQDFGVRIDVDTRRLTFLQLTADKGWQKWQNDKMTNQTTLKEGLQLDFELGGGAWQKDDRLFNPGSLFDEEMFADEKKEQKQEPAPQLFVLSSGEVTPFTLSIFPKGQEPDEQWRVTAQENGTLRLLAPGESDEE
What is the function of this protein?
Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm (By similarity).  Part of the pseudopilus tip complex that is critical for the recognition and binding of secretion substrates (PubMed:18241884, PubMed:24316251).
What are the official names of this protein?
Type II secretion system protein H, T2SS minor pseudopilin H, Cholera toxin secretion protein EpsH, General secretion pathway protein H.
What is the protein family that this protein belongs to?
Belongs to the GSP H family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: MFTB_MYCUA
Sequence: MRGLLTVPAPAQAAAGAGAFDPDRGWRLHAQVAVRPEPFGALLYHFGTRKLSFLKNRTILAVVRSLADHPDVRSACRAAGVDDSEHAPYLHALSVLAGSHMLVPQEADQ
What is the function of this protein?
Peptide chaperone involved in the biosynthesis of the enzyme cofactor mycofactocin (MFT).  Binds MftA and MftC with high affinity, and is essential for MftC activity on MftA, likely via the formation of a ternary complex.
What are the official names of this protein?
Peptide chaperone MftB.
What is the protein family that this protein belongs to?
Belongs to the peptide chaperone MftB family.
Protein: MACB_NITEU
Sequence: MVSTDLPPLIELRGIRKRYGGGDKPEVEVLHGIDLDIRAGEFIAIVGSSGSGKSTLMHLLGCLDRPSSGSYRFAGEDVSTFGSDELAWLRRKAFGFVFQGYHLIPTESARENVEIPAIYAGLPPGERMQRAADLLGRLGLSDKLNNRPNQLSGGQQQRVSIARALMNGGHIILADEPTGALDSRSGAEVMELLRELAGAGHTVILITHDRDVAAQAQRVVEIRDGRIVADSVTDRQPSEQPLLHHAGLSSLEMTQAHEDTGTPFWQGLHETIRAAWRVMWIHRVRTSLTLLGIVIGVASVIVMLAIGEGTKQRVIDQMGSMGTTIMYMSSDVPSTGGPVGVITEEDLDEVARLPEISRVMPVIGDPILVRHQNVDKQIYVFSSPYIMPMVHHWRVAQGRFFTETEDRELAPVVVLGHKIYRSFFPHLSNPVGQYLLIGTSPFEVIGVMAERGAESGSQNYDDMVFIPYRAGRARVYQAQEQPDYIVMEAASMDQVQEAEEAIRALLLERHGREDFRIGNAAARLKTQLETRDTMTRMLGLVAAVSLLVGGIGVMNVMLMTVRERTREIGIRMATGAREYDILSQFLIEAMLVTITGGTVGVILGLTVGALLVFWEVPVVFSFGVMIGAFACAVITGLIFGYMPARTAARLDPVVALSSE
What is the function of this protein?
Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation.  Confers resistance against macrolides.
What are the official names of this protein?
Macrolide export ATP-binding/permease protein MacB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: G6PI_COXB2
Sequence: MSLVESPPWQALKSKYQELSSLHMRDFFAQDKKRGTRLSLEAAGLYFDYSKNRVDEKTIDLLCESANACNLPLRIEQLFSGKLTNESGEMVGFHTALRQVNNFSFKTNNNAIQEIHASWEKIKKLSIRIREGDYKGFTNKSITDIVNIGIGGSSLGPQMAYNALKPYVKAPLRCHFISNLDDTDFYETVRTLNPETTLFIITSKTFTTKETLENARRATEWLMQAAKKENLIQTHFMAVTAAPEKAHEFGIQKDNIFMLWPWVGGRFSVWSAAGLSLAIAIGWEEFFEFLRGAHAMDTHFRQAEFNKNMPILLALLSIWYINFFHAKTQAIIPYSQRLVYLPDYLTQLHMESLGKSVQLDGSAVHWQTGAVVWGDLGTNSQHSFHQLFLQGTMVIPVDFIAFLKNSRESHWQLPLIANCLGQSQTLMEGYDKEGVMRDLINQGIEHEKAEKLATYRLIRGNNPSNTIILEELNPYSLGSLLALYEHKVYVQSVIWNINPFDQWGVERGKHLAKDILQALQAETDQSSFDSSTERLINYVLKIKGNRP
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KUP_CORGL
Sequence: MKSARPKSVAPKSGQALLTLGALGVVFGDIGTSPLYSLHTAFSMQHNKVEVTQENVYGIISMVLWTITLIVTVKYVMLVTRADNQGQGGILALVALLKNRGHWGKFVAVAGMLGAALFYGDVVITPAISVLSATEGLTVISPSFERFILPVSLAVLIAIFAIQPLGTEKVGKAFGPIMLLWFVTLAGLGIPQIIGHPEILQSLSPHWALRLIVAEPFQAFVLLGAVVLTVTGAEALYADMGHFGARPIRVAWFCVVMPALILTYLGQGALVINQPEAVRNPMFYLAPEGLRIPLVILATIATVIASQAVISGAYSLTKQAVNLKLLPRMVIRHTSRKEEGQIYMPLVNGLLFVSVMVVVLVFRSSESLASAYGLAVTGTLVLVSVLYLIYVHTTWWKTALFIVLIGIPEVLLFASNTTKIHDGGWLPLLIAAVLIVVMRTWEWGSDRVNQERAELELPMDKFLEKLDQPHNIGLRKVAEVAVFPHGTSDTVPLSLVRCVKDLKLLYREIVIVRIVQEHVPHVPPEERAEMEVLHHAPIRVVRVDLHLGYFDEQNLPEHLHAIDPTWDNATYFLSALTLRSRLPGKIAGWRDRLYLSMERNQASRTESFKLQPSKTITVGTELHL
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FLIT_ECOLC
Sequence: MNHAPHLYFAWQQLVEKSQLMLRLATEEQWDELIASEMAYVNAVQEIAHLTEEIDPSTTMQEQLRPMLRLILDNESKVKQLLQIRMDELAKLVGQSSVQKSVLSAYGDQGGFVLAPQDNFS
What is the function of this protein?
Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD.  As a transcriptional regulator, acts as an anti-FlhDC factor; it directly binds FlhC, thus inhibiting the binding of the FlhC/FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons.  As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus.
What are the official names of this protein?
Flagellar protein FliT.
What is the protein family that this protein belongs to?
Belongs to the FliT family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: DAPF_BACC7
Sequence: MSQFSFTKMHGLGNSYIYVNMFEEQIPEEDLALVAEKVSNINTGIGADGMILICPSDVAPVKMRMFNNDGSEGKSCGNGLRCVAKYAYEHKLVEDTVFTIETLAGIVTAEVTVEEGKVTLAKIDMGAPRLTRAEIPMLGEGETPFIRENFLYNNHRYAFTAVSMGNPHAVIFVDDVEQAPLTTLGPVLETHEMFPERVNVEFIEILNEEEMNFRVWERGSGVTQACGTGACAAVVASILNGKMERGKEITVHLAGGDLMIAWTEEGNVLMKGPAEVICHGVYEYKIEA
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ES1IB_ODOIS
Sequence: MFTLKKPLLLIVLLGIISLSLCEQERAADEDEGTKIKRRIFSKIGGKAIKNLILKGIKNIGKEVGMDVIRTGIDVAGCKIKGEC
What is the function of this protein?
Has antimicrobial activity against Gram-negative bacterium E. coli ATCC 8739 (MIC=3. 1 ug), against Gram positive bacteria S. aureus ATCC 6538 (MIC=3. 1 ug), methicillin-resistant S. aureus ATCC 43300 (MIC=12. 5 ug), B. subtilis ATCC 6633 (MIC=12. 5 ug) and against fungus C. albicans ATCC 90028 (MIC=50 ug).
What are the official names of this protein?
Esculentin-1ISb.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Esculentin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: FPG_KLEP3
Sequence: MPELPEVETSRRGIEPHLVGVTILHAIVRNGRLRWPVSEEIYRLSDVPVLSVRRRAKYLLLELPDGWIIVHLGMSGSLRILSEELPAEKHDHVDLVMSNGKVLRYTDPRRFGAWLWTKTLEDHPVLAHLGPEPLSDEFNADYLQQKCAKKKTAIKPWLMDNKLVVGVGNIYASESLFSAGIHPDRLASSLSREECEQLVKVIKLVLLRSIEQGGTTLKDFLQSDGKPGYFAQELQVYGRKGEPCRICGTPVVGTKHAQRATFYCRQCQK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: PTC2_MOUSE
Sequence: MVRPLSLGELPPSYTPPARSSAPHILAGSLQAPLWLRAYFQGLLFSLGCRIQKHCGKVLFLGLVAFGALALGLRVAVIETDLEQLWVEVGSRVSQELHYTKEKLGEEAAYTSQMLIQTAHQEGGNVLTPEALDLHLQAALTASKVQVSLYGKSWDLNKICYKSGVPLIENGMIERMIEKLFPCVILTPLDCFWEGAKLQGGSAYLPGRPDIQWTNLDPQQLLEELGPFASLEGFRELLDKAQVGQAYVGRPCLDPDDPHCPPSAPNRHSRQAPNVAQELSGGCHGFSHKFMHWQEELLLGGTARDLQGQLLRAEALQSTFLLMSPRQLYEHFRGDYQTHDIGWSEEQASMVLQAWQRRFVQLAQEALPANASQQIHAFSSTTLDDILRAFSEVSTTRVVGGYLLMLAYACVTMLRWDCAQSQGAVGLAGVLLVALAVASGLGLCALLGITFNAATTQVLPFLALGIGVDDIFLLAHAFTKAPPDTPLPERMGECLRSTGTSVALTSVNNMVAFFMAALVPIPALRAFSLQAAIVVGCNFAAVMLVFPAILSLDLRRRHRQRLDVLCCFSSPCSAQVIQMLPQELGDRAVPVGIAHLTATVQAFTHCEASSQHVVTILPPQAHLLSPASDPLGSELYSPGGSTRDLLSQEEGTGPQAACRPLLCAHWTLAHFARYQFAPLLLQTRAKALVLLFFGALLGLSLYGATLVQDGLALTDVVPRGTKEHAFLSAQLRYFSLYEVALVTQGGFDYAHSQRALFDLHQRFSSLKAVLPPPATQAPRTWLHYYRSWLQGIQAAFDQDWASGRITCHSYRNGSEDGALAYKLLIQTGNAQEPLDFSQLTTRKLVDKEGLIPPELFYMGLTVWVSSDPLGLAASQANFYPPPPEWLHDKYDTTGENLRIPAAQPLEFAQFPFLLHGLQKTADFVEAIEGARAACTEAGQAGVHAYPSGSPFLFWEQYLGLRRCFLLAVCILLVCTFLVCALLLLSPWTAGLIVLVLAMMTVELFGIMGFLGIKLSAIPVVILVASIGIGVEFTVHVALGFLTSHGSRNLRAASALEQTFAPVTDGAVSTLLGLLMLAGSNFDFIIRYFFVVLTVLTLLGLLHGLLLLPVLLSILGPPPQVVQVYKESPQTLNSAAPQRGGLRWDRPPTLPQSFARVTTSMTVALHPPPLPGAYVHPASEEPT
What is the function of this protein?
Plays a role in the control of cellular growth (By similarity).  May have a role in epidermal development.  May act as a receptor for Sonic hedgehog (SHH).
What are the official names of this protein?
Protein patched homolog 2, PTC2.
What is the protein family that this protein belongs to?
Belongs to the patched family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RTC1_CANDC
Sequence: MSQPNSQGQSNLAKFAFNIYGTLSTNSSTPQSHEISPSSSLGSSRSNKQTNQYSSQETNNNRLSYYCEKEIMSLSQLNYPLSIGGYNGDLQHHVVIGGKNYLRLLCVSETQQRIISDINLLESKSIYNSRATNKLINVNTIKTYADTIAAGLSNGVVLIYRVSPNGQSKVVGKYSDHSRTINSLDFIDSENQLLSGSQDGTIKLWDLRSSSTKPVMTIQANLHSDPIRACQYSRHSAVRNKICVLSVHDSGALCKFDLRTKNGGKVYSPEKKWNLHTGPVLSLHIHPEKEYVVTGGRDKRISVFNYGDGQSRNTPDSLINTYGPVVKVRWSTYANTKEIVEEFEENQQPNPNPLYNYDIACSYLNDDPTIAIYNLGRKFIPKQIIHSKKPVQNFIWAQNNSKSRKIWTLSKPNSFNSYNLYGLDDSDVSRPIEDLSNVAMTWDNNNDFCAVSQARYDYDLESFGNAINETYEDNYDTERNCSLDNEEFVHSQANSLTASPIEKPQLTRSMTYNPVQSFSTFSPAPVARTATGFLQNEPVTPSSSSSIPNMHLSSSRPKLTRNTSQTTQDSSSSQLSSVIPPPSSSQTYSSPQYKRNQSSRCLNTPAYVIPVSIPVPSNDEYVFQKLSSESLVNIPDGFTLVDVCLINASVAASVNNNRTSQVWKLLAVSIQEEFESGSKLRRILGPETETVSKIPQEVHESLAKTNEALSSDIAKSNSVSSVLGNFVESFKSTSTSGSQFGKQNDKDDRKLQNKNSSGNLMDMINKASRNSSFSTTSFRLKEQERREHELRNTQNFRDENEKVSTHSKSAPISISSHPEDLDDENMSATNSAGLKSSPPSVGVSIPSTRTFSSSLASSPKSIRIMNGVNSNVARSQPSPPVQTWLKQRNFDVSNGVTMMGTSGLSLALKRNKTNEEGCEFVKVWKFKSLLRKSLDYAALQGDIIFCSTVALLFYDIVPDVISQFECLEWLSIYIEILQRKRLFVNAINVIKCATADIQEKLQKLYCSDLSLRFYCSRCQALLVNDKSKFSGKGEFGYWYCDECSRLQSQCVYCNEPCKGLAVTVGLKCGHQGHFGCLKEWFIEDQNTECPGGCDYQVI
What is the function of this protein?
May be involved in a process influencing telomere capping.
What are the official names of this protein?
Restriction of telomere capping protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat RTC1 family.
What are the subcellular locations of this protein?
Vacuole.
Protein: VF198_IIV3
Sequence: MKVDFEFVSTHRNRTLWPNPCCFEVGWSSTAPSNAINAYDPVSDQVPLLVWVGSDQKVTGKLIAHVGDWMVVAFPIGAVSPKVNNYRGMQLSMGSVVTRIVANRRVSSDAQWDYFKVQIDPSLEQQVPDSVVSLEPISVPGTWFVPGGSDVVNAYSGMYLYNETLGQWVVIRAYDHTFHLAIPDSIMTGWDVTHQYSIRPQLPSLSNFLLDAGSTTTLIATRLASHARLGDWIRIVTTGECAKVVNVLDGSIGVSPPLSRAFFAGTPVELLGQIYDNYQTLSYPGLVIGNQEQSAYQVTLVSAFIPNVETENGGYPNEYPFLYVEFSDTHYPYQNNLFSNNHSNKSWFKVTTPTGLYQSKERWIKFTGDYSFKTIRFKPTSNFRIVWRTPSGAEVKFTQPDTQSPSSPDPSLQTFIQFNMFKV
What are the official names of this protein?
Uncharacterized protein 069L.
What is the protein family that this protein belongs to?
Belongs to the IIV-6 198R family.
Protein: TRPB1_CHLCV
Sequence: MYTCDTCEEDLDLSLDLGETYEELETYGGQYVPLELVKPLEDLDRSYEQLKKDPQFRETFHHILKNYAGRPTPLTEVKNFSRAINGPRIFLKREDLLHTGAHKINNVLGQCLIAKFQGKTRVVAETGAGQHGVALAAAAAYLGMECVIFMGETDINRQKPNVDRIRVLGAEVVSVKRGNSGLKEAVDAAIEDFIFKHDHTHFCIGSALGPYPYPKIVRDFQSVISLEVKSQIKEYTDRDPDILIACVGGGSNAIGFFHHFIPNTKVKLVGVEGGGLGVESGKHAARFATGKPGVVHGFHSYVLQDEDGNCADTYSISAGLDYVSVGPTHAEMHESGRAQYTYATDDEALEAFRLLSKTEGIIPALESSHALAHMIKIAPSLDKDTIAIVNLSGRGDKDLSQIIDLDKRKKHS
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain 1.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: IAFRS_STRMQ
Sequence: MHTHASRPHARQSALPRRAALFDFPASADLSPDTGAARQHTIQWLSRFRVFENHASVEEYDALRFDVLTGLFYPRATGADLNLGSDLVGWYFVFDDQFDGELGCRPEEVARLVADVIRVTEEDMAPGGTGGGEGPLLESFRDLWHRINSGRPRVWRDRFRHHWLEYLHSYHREALERTGAAPADGGGDAPRSVEDVLALRRHSIGVQPCLDLNEPFGGYTLPSALHGGFPLARMREATDDVVVFTNDIASLDKELAVGDVHNSVIVQWKLAGGGVEDAVRHIAGLANARYGWFEETAARLPELLAEAGADPGTHRAVGRYVDGMRHVMTGNLGWSLRTARYDERGTEAVSGGRERPWARLTGAEDLIRAGRGAPPPPGSGPDTRQPMPSEPSQLA
What is the function of this protein?
Catalyzes the cyclization of farnesyl diphosphate (FPP) to isoafricanol.
What are the official names of this protein?
Isoafricanol synthase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: R1A_LIYV9
Sequence: MALEVESAFSLSYLLKENKQTSNNLFSLIQVPYTKMTHAKGKKTHLLRCILGSPFETLTKSSIRRSLKNLREVCNLPYCNFKKIPKNISYKYQNPFLKLYEINNNFINCKVGATGNTNSTYDWRNLSTIGNGWSVTSYHNDSVSRLHVSMVNNIPNSNTKKLSWWVTRVRSKNPWKRPYKVIYQRDFRDDGIKPYVSEFILYAPKNRADLEMQSILLSSVECFQDIKYALNYWTNLKFKEICNSALKRFTQTNIIITPVKPRVVSVNKAREVSSSVEVKLQRYEREGEVFVVSKAGKEDTRVLNDDNAIRNLFNATLNGGKYKLHPEAKSATGKRFKYYKDGFCWLDVFADANRRIPEWVKPHCLLTGSVLMSCGLWDFAKRKMVSVSHGLLHYDRKLERSSARAGVRDFVGASNEAVQREDFRDLDLRVEEFAERVLETANLRSDNRLIDNILTRASDYINKKSKESKELDINVCLSMDEKKMITNLFPDIQMSFNQKSYSNHGVFNAMRACENFYFSRKFKNSDYIDAGGDVVSTLRSKNHNVHICSPRLDLKDAARHIQRATVIDGLKGYGETISFCTNKTEDCAVNRDIIIAVEVYDMTLRDMAKAMLSHGSRKFEFSCIIPPEIFTKECNVELYEGRLKVTRIGDNVEYYYGSNGETFSHSCQTLKDILSVQVFQFGGRVFKKTLEHSRGQLHFFSICICEKIEPGSVKLKTYYQRSELDKVTLRIPVKDSFGVVTHYIIKEDREFVSSMIEYVANTGIKIDDKMVEWTYSQYRAKKTVTIKSGKVTQKETRIRKELIPGFIAIIMSEGIRAREKTHYLAKMLYTSHYKPSIVNIIFRLIMHFLGGTKRFIYESLVDCLKFLTNSDYIDTIVNTESRIEDLDKWFVFEQNVTITTDAEDQPSILEQSVKTFLSKYSEDVYERGDRSEFELEEFSSEQDLVDQLLNSGGGSKEDEWFYSYIFSIVRTKCTLSLAWRWTNRIFNFITSCRAKGKDFVKYIYEIIKIIINKPWEALCHYLVQGYKTVLKIPMTCVDSVNYLKRKSLEKILSYFSHERADDEYIFPGYDSDFSEESGDYGDENTELDSRSRCTVIKSKVEMLFRNIKGHIEKFLQRCGIIDQYNKIYHWFKSILTDVDCFNSVLNFITHTGCDALLAVLTGHFSIASCALKFMTDVVIEKNLSEKHHTTTKLIAGNLTQCIYKLDFIHPIWIPIRWGVKEISKIHIKKKLLNWRSTKEVTNESICKDLVHKSYIKYFDIKKAVWLLWFSLLIIFLHPTLGFFILFSIYPAIEIKRYYNNVVCFNNIKMSYPHVIDRLGGTYNFAKLKKAVREKFSENKSQGVKISEIPAEKDEDVMPPLEEVETPKRSVGRPSSKQDDIEDECNIKEDPTESLNFSNIEATSNRYDTLRVGNSKLCKFLRFYPKSKCYANIQTGDLIRDSIEEFYHLERSKLDIEISKMQRVVEIMNDTGRMLDNVRRMIDDRSMYVTLDGVSWYRLGCKDKNPAKEDFKAIFDHNFNIMEGNAKVKEFAVSSDEWRGMYSNERCRAIEQLFNDNNEMVRRPDVNGLKFYNKPPGAGKTTTIAKLMSKDLKNKVKCLALSYTKVGRLELIDKLKKDGIEKPEKYVKTYDSFLMNNDNILEIVNLYCDEVFMMHAGHFLTLLTKIAYQNGYCYGDVNQIPFINRDPYTPAYLSREFFRKQDLNYDTYTYRCPLDTCYLLSNLKDEMGNIIYAGGVKNVNEVYPTIRSLNLFGINVVGEVPVEYNAKYLTFTQDEKLNLQRHIDSQGGCRNAVSTVNEAQGCTFSEVNLVRLVQFDNPVMSDINQFVVAISRHTTTFKYFTPHSRLNDRVSNAISSLQSVSDFVLKDYHFRQCL
What are the official names of this protein?
Replicase polyprotein 1a.
Protein: FABZ_CHLTR
Sequence: MNEKPVLGIQDIQNLLPHRYPFLLVDKILSYDLNTRSVVAQKNVTINEPFFAGHFPGAPIMPGVLILEALAQAAGVLLGIILENDRDKKIALFLGIQKAKFRQPVKPGDVLTLKAEFSLISAKGGKAFAQAFVGSQVVAEGELSFVLVKKESI
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABZ_OCEIH
Sequence: MMDVEQVKEIIPHRYPFLLVDKVVEIQEGEKVTALKNVSVNEPFFQGHFPEYPVMPGVLILEALAQTGAIAVLNIEENKGKIGFLAGVDKCRFKRQVKPGDQLNLQVEIIRMKGPIGKGKGIATVDGEVACEAEITFAIK
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_EHRRW
Sequence: MIGSITGNVEEIRDSYIILNVGNIGYIIYVSHKVLQTCKVGDNIKLYIETYVNRDNITQLYGFLNRQEQDYLKMLVTINGINYKTALSILSKLSPEQIFSAVVNNDKIAFKGNGIGEKLAGRIITELQYKINKMPIEETFSIIENDDSLAALISLGYEKLKAFNVIQEIKSKTPDASTQEVIRKALQKLSQ
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: RM06_PROWI
Sequence: MKTLSILDTIIKIPEKIEIHPTTTEYIYTITGPLGSSSINLKKLDKNGIACINFDIQNKQVLIRSLYPKYNGLYKKLIENKFLGVSRGFCVYLEIVGVGYRAALLSSSLQNSTKDTNDTIVLKLGHSHDIHYKVPNGVRVFLQSPSEICIFGVDLNQVTQVAHSIRNTRPPSVYKGKGIRYTNEKIVTKTGKRK
What are the official names of this protein?
60S ribosomal protein L6, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: VG55_BPMD2
Sequence: MSESILEEAQRLIHGERNKNYGHPRENFKDIALLFSGYLEKEISDIDVANLMILMKIARVKGTGYHRDSFTDMAGYAGCVERIYEEPVEGEPRQWDTLADVPKDVKTVRSAGNAFWSRYPDYNERLWGHRDGFKLDHAKISEGPFVEVLGE
What are the official names of this protein?
Gene 55 protein, Gp55.
Protein: PDP_STAAS
Sequence: MRMIDIIEKKRDGHTLTTEEINFFIDGYVKGDIPDYQASSLAMAIYFQDMNDDERAALTMAMVNSGDMIDLSDIKGVKVDKHSTGGVGDTTTLVLAPLVAAVDVPVAKMSGRGLGHTGGTIDKLEAIDGFHVEIDEATFVKLVNENKVAVVGQSGNLTPADKKLYALRDVTGTVNSIPLIASSIMSKKIAAGADAIVLDVKTGSGAFMKTLEDAEALAHAMVRIGNNVGRNTMAIISDMNQPLGRAIGNALELQEAIDTLKGQGPKDLTELVLTLGSQMVVLANKAETLEEARALLIEAINSGAALEKFKTFIKNQGGDETVIDHPERLPQAQYQIEYKAKKSGYVTELVSNDIGVASMMLGAGRLTKEDDIDLAVGIVLNKKIGDKVEEGESLLTIHSNRQDVDDVVKKLDSSITIADHVVSPTLIHKIIIE
What is the function of this protein?
Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
What are the official names of this protein?
Pyrimidine-nucleoside phosphorylase, PYNP, Py-NPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: TRMD_HYDCU
Sequence: MRFDVITLFPEMFSALTESGVSRRAYQDQLYQFKTWNPRTYTTDRHKTVDDRPYGGGPGMLMMYPPLKKTVDAITDEVGEKPYVVYLSPQGRPLTQQKLSELQSHSNVTLVCGRYEGIDERFIETVVDEEICVGDFIVSGGELPAMMLMDGMIRLIPGALGHNQSAEQDSFSDGLLDCPHYTRPVEVDGMGVPEVLQEGHHAKIEQWRHEQKLLRTKQKRPDLYTAYLAKHTETQDK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.