PharMolix/UniProtQA huggingface dataset:
Protein: RUVA_ENTFA
Sequence: MYEYIIGKVTFVSPYYIVVETNGIGYQISVDNPYRYSGKMDTDIKLYLHQVVREDAQLLFGFGSLEEKQLFLKLISVSGIGPKSGLAIMASVADHGGLINAIEGEDVTYLTKFPGVGKKTAQQMILDLKGKLGELESSEAAVAAMTATEAVTTSNQALAEALEALSALGYSDREIKRITKQLEALGETTTDVYLSNALKFMMKR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: CBID_PROM2
Sequence: MKKGFSLPLWVAGAARSALKKLVGLSFENYELIKIPYEKKEIKIEIHSVGLLKNDSHALGITFAKSGLDLDITQNLEIWTIASLEKISFENSLQRVPINIIAGSGVGIKEDTSEICISNFAKEVLYENLLDIIPEGFNLKLEIIFPNGAFLAERTSNQSFGIVDGLSIIGTSAETYSSASPDQLEEAKNNLAKLIQNDFKGEVVFVIGENGLNLLKTHNVNLPIIKIGNWIGPLLVDAAIKKVKTVILFGYHGKLIKLAGGIFHTHNHLADGRIEILVYLAVQENVPFEIIVKLSKLDNIENALLFLEKFNQSTADKLFKRLSNTIEKRSFAYVNRYVKTDMEIASIIFDRKRKIRWAGIYGKKYISYFQ
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: ARO1_BLAGS
Sequence: MGVPTKISILGRESIVADFGIWRNYVAKDLLNSCSSSTYILISDTNITPLYLDGFQKSFDDAAANLSPKPRLLTYEIPPGESSKSRETKAGIEDWMLTRQPPCGRDTVIIALGGGVIGDLIGFVAATYMRGVRFVQVPTTLLAMVDSSIGGKTAIDTPNGKNLIGAIWQPQRIYLDMEFLNTLPEREFINGMAEVIKTAAISSEEKFAALEDDAEIILAAVKSKNTPERPRFSGIEETLKRTILSSAEFKAQVVSADEREGGLRNLLNFGHSIGHAIEAILAPQVLHGECVAIGMVKEAELARHLGILNNVSVSRISKCLASYGLPTSLKDERIRKLTADKHCSVEQLITYMGVDKKNDGPKKKVVLLSAIGRTHEPRASTVSNEEIQIVLAPSIEVSPGVPKNLNVTCTPPGSKSISNRALVLAALGSGTCRLKNLLHSDDTEVMLNALERLGAATFSWENEGEVLVVNGKGGKMKASPDELYLGNAGTASRFLTTVATLAQKSSVDSSVLTGNARMKQRPIGDLVDALAANGAGVEYLENSGSLPLKIAASGGFAGGEINLAAKVSSQYVSSLLMCAPYAKKPVTLRLVGGKPISQTYIDMTTTMMRSFGIDVKKSETEEHTYHIPLGFYISPAEYIVESDASSSTYPLAVAAITGTSCTVPNIGSKSLQGDARFAVEVLRPMGCTVDQKDFSTTVTGPANGILRPLPNVDMEPMTDAFLTASVLAAVARGGGSNHTTRIFGIANQRVKECNRIKAMKDELAKFGVTCREHDDGLEIDGIDRSTLRHPSDGVYCYDDHRVAMSFSVLSLVAPQPTLILEKECVGKTWPGWWDSLAQTFKVKLDGKEVEKKTGTGGIVHLDKPAASIFIIGMRGAGKTTSGVWVSKALQRPFIDLDDELERTEGMTIPEIIKQRGWEGFREAELSLLRRVMTEKPTGYIFACGGGIVETPEARKLLIQYHKTKGNVILVMRDIKEIMDFLKIDKTRPAYVEDMMSVWLRRKPWYQECSNVQYFSRLTGLDGMAQVLGGFNRFLKVITGQVDSLAQMRSKENTFFVSLTLPDLAPAAPILKEVTLGSDAVELRVDLLKDPQSDSEIPSVDYVAEQISVLRSRTSVPLVFTIRTKAQGGRFPDDAYDAALQLYRLAIRMGSEFVDLEISFPEQLLRTVTEMKGFSKIIASHHDPKGELSWANGSWIQFYNKALQYGDVIKLVGVARSLDDNASLKKFKTWAEEKHDVPIIAINMGDKGQLSRMLNGFMTPVSHPSLPFKAAPGQLSAREIRKGLSLIGEIKSKKFAVIGNPVSASRSPAMHNALFRQMGLPHTYGTLETEDPEIVKKFIRSPDFGGASITIPLKLDIMPLLDEIAPEAVSIGAVNTIVCAPPAPDDQSQAPRLIGRNTDWQGMVRCLSDAGAYPAATPTTTSAGLVIGGGGTARAAIFALQSMGYSPIYVVGRSPDKLSSMTSTFAPDHDIRILEDVKALESLPTVAIGTIPGDKPIEPHMREVLCELFDLCEKANSDAEQARGISTKRILLEMAYKPSVTSLMQLASDSGWTVLPGLEALVAQGVYQCEYWTDITPVYEDARNAVMGVQPKDDDIST
What is the function of this protein?
The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.
What are the official names of this protein?
Pentafunctional AROM polypeptide.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the shikimate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAAF8_HUMAN
Sequence: MASNDKGMAPSLGSPWASQMGPWDAILKAVKDQLPSLDSDSPLSDYGEEELFIFQRNQTSLIPDLSEELAEDPADGDKSRAWVAAAEESLPEPVLVPAELATEPGCRQNTRTKDASSQEGRDPGRPFESSGEVSALLGMAEEPPRWLEGDLGSLSFNTKGSQGPPWDPQAEATLSCHEGDPKAEPLSTASQESVNRRALRQERRKMIETDILQKVTRDACGPTSSDKGGVKEAPCHAAESAPRSKMPLVEPPEGPPVLSLQQLEAWDLDDILQSLAGQEDNQGNRAPGTVWWAADHRQVQDRMVPSAHNRLMEQLALLCTTQSKASACARKVPADTPQDTKEADSGSRCASRKQGSQAGPGPQLAQGMRLNAESPTIFIDLRQMELPDHLSPESSSHSSSDSEEEEEEEMAALGDAEGASPSSLGLRTCTGKSQLLQQLRAFQKGTAQPELPASKGPAGGRAQAPEDTAGSRTGRKQHMKLCAKGQSAQARLPRGRPRALGDVPEPGAAREALMPPLEQL
What is the function of this protein?
In cyliated cells, dynein axonemal particle-specific protein required for deployment of ODA to the axoneme.  Interacts with outer dynein arm (ODA) subunits.
What are the official names of this protein?
Dynein axonemal assembly factor 8, Dynein axonemal-associated protein 1.
What are the subcellular locations of this protein?
Dynein axonemal particle.
Protein: RDRP_I72A3
Sequence: MDVNPTLLFLKVPAQNAISTTFPYTGDPPYSHGTGTGYTMDTVNRTHQYSEKGKWTTNTETGAPQLNPIDGPLPEDNEPSGYAQTDCVLEAMAFLEESHPGIFENSCLETMEVVQQTRVDKLTQGRQTYDWTLNRNQPAATALANTIEVFRSNGLTANESGRLIDFLKDVMESMDKEEMEITTHFQRKRRVRDNMTKKMVTQRTIGKKKQRVNKRSYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRGFVYFVETLARSICEKLEQSGLPVGGNEKKAKLANVVRKMMTNSQDTELSFTITGDNTKWNENQNPRMFLAMITYITKNQPEWFRNILSIAPIMFSNKMARLGKGYMFESKRMKLRTQIPAEMLASIDLKYFNESTRKKIEKIRPLLIDGTASLSPGMMMGMFNMLSTVLGVSILNLGQKKYTKTTYWWDGLQSSDDFALIVNAPNHEGIQAGVDRFYRTCKLVGINMSKKKSYINRTGTFEFTSFFYRYGFVANFSMELPSFGVSGINESADMSIGVTVIKNNMINNDLGPATAQMALQLFIKDYRYTYRCHRGDTQIQTRRSFELKKLWEQTRSKAGLLVSDGGPNLYNIRNLHIPEVCLKWELMDEDYQGRLCNPLNPFVSHKEIESVNNAVVMPAHGPAKSMEYDAVATTHSWIPKRNRSILNTSQRGILEDEQMYQKCCNLFEKFFPSSSYRRPVGISSMVEAMVSRARIDARVDFESGRIKKEEFAEIMKICSTIEELRRQK
What is the function of this protein?
RNA-dependent RNA polymerase which is responsible for replication and transcription of virus RNA segments.  The transcription of viral mRNAs occurs by a unique mechanism called cap-snatching.  5' methylated caps of cellular mRNAs are cleaved after 10-13 nucleotides by PA.  In turn, these short capped RNAs are used as primers by PB1 for transcription of viral mRNAs.  During virus replication, PB1 initiates RNA synthesis and copy vRNA into complementary RNA (cRNA) which in turn serves as a template for the production of more vRNAs.
What are the official names of this protein?
RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 1, PB1, RNA-directed RNA polymerase subunit P1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses polymerase PB1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: ZPR1_SCHPO
Sequence: MAEEKKEELFTSIGNAAQNVSTAEDREGNGVQEVESLCMECGKNGTTKLLLTVIPYFREVVLMSFECPHCGFKNAQVQHAETIQPEGSKITFHVEDKEDLNRTVVKSQEAIVSIPEIQLEIPGRLGQLTTIEGILSNVVDDLSKEQESRKESAPQLYDQINAFIEKVNSLRSGSVPFTITVDDITGNSWIEMKPGRDGDRWSQVSYKRTLEQNTKLGLVDTDQPEDVKTQTNNASNTLKHDATAVEVDPNEVHTFHATCPSCSHQCDTHMKLLDIPHFKEVIIMSTVCDRCGYRSNEVKTGGEIPPKGRKITLKVMDAEDLSRDILKSETASLKIPELGLDLFPGTLGGRFTTIEGLLAQVYDELYGRVFSQETDSMTPEQVANWQQFLCNLTAAREGATQFTLILDDPLSQSYLQNYYAPDPDPNMTIEEYERSFQVNEELGLNDMKTENYEKDGGKK
What is the function of this protein?
Acts as a protein folding chaperone for elongation factor 1-alpha.
What are the official names of this protein?
Zinc finger chaperone zpr1.
What is the protein family that this protein belongs to?
Belongs to the ZPR1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates to the nucleus after nutrient stimulation.
Protein: GCSH_PYRFU
Sequence: MIEVGEYKIKEGLYYTKEHEWVQVLEDGTVLVGITDYAQKELGDLAYVELPEVGKVVEKGDVLCEVESVKAVSEVYAPVSGEVIEVNEELADSPEKINEDPYEAWIAKIKPKNLEEELKELMDAKAYAEYLKTL
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Probable glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: NBP35_YARLI
Sequence: MPSLVDPVANKTDEGNNRTDLKAPEPEHCPGTESEEAGKADACQGCPNQDICASAPKGPDPDLPLIKDRMKGVKHKILVLSGKGGVGKSTFSSLLGWGFASDLDREVGLMDIDICGPSLPKMMGSEGEQIHTSLSGWSPIYVSDNLGMMSVGFMLPNQDDAIIWRGAKKNGLIKQFLKDVDWGNLDYLVVDTPPGTSDEHLSVTQYLKESGVDGAVVITTPQEVALLDVRKELDFCRKSGIKIIGLVENMSGFVCPNCKGESFIFAPTTGGGKALAEEFNIPFLGSVPLDPRIGKSCDHGESFVEEYPDSPATTAILDVIRQIREAVGDPQEDEDDDMDE
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery.  Required for maturation of extramitochondrial Fe-S proteins.  The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.  Required for biogenesis and export of both ribosomal subunits, which may reflect a role in assembly of the Fe/S clusters in RLI1, a protein which performs rRNA processing and ribosome export.
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor NBP35, Nucleotide-binding protein 35.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: BBE26_ARATH
Sequence: MGISKPLPLFSILVLYFSLYTITPTSSLASLQDQFINCVQRNTHVYFPLEKTFFAPTKNVSMFSQVLESTAQNLRFLKKSMPKPGFIFSPIHESHVQASIICSKKLRMHLRVRSGGHDYEGLSYVSQIDKPFILMDLSKMRQVNINIQDNSAWVQSGATVGELYYRIAEKSKVHGFPAGLCSSLGIGGHITGGAYGSMMRKYGLGADNVLDAKIVDANGKLLDRAAMGEDTFWAIRGGAGGSFGIILAWKIKLVPVPKTVTVFTVTKTLQQDVGNKIISKWQRVADKLVEELFIRVLFNVAGTGGNKTVTTSYNALFLGGKGTLMNVMKKSFPELGLTFKDCIEMSWLESIAYISGFPTHTPTNVLLQGKSPFPKVSFKAKSDFVKTPIPESGLQGIFKKLLKEDIPLMIWNPYGGMMAKIPESQIPFPHRKGVLFKVQYVTSWLDSDKRPSRHINWIRDLYSYMTPYVSSNPREAYVNYRDLDLGRNTKDVKTCIKQAQVWGANYFKNNFNRLMMIKAKVDPENFFRHEQSIPPMM
What are the official names of this protein?
Berberine bridge enzyme-like 26, AtBBE-like 26.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: CYC_PICST
Sequence: MPAPFEKGSEKKGATLFKTRCLQCHTVEEGGPHKVGPNLHGIMGRKSGQAVGYSYTDANKKKGVEWSEQTMSDYLENPKKYIPGTKMAFGGLKKPKDRNDLVTYLASATK
What is the function of this protein?
Electron carrier protein.  The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase.  Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
What are the official names of this protein?
Cytochrome c.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane.
Protein: RS11_LYSSC
Sequence: MARKQQTRKRRVKKNIESGIAHIRSTFNNTIVTITDMQGNAVSWSSAGALGFRGSRKSTPFAAQMAAETAAKTSLEHGLKTLEVTVKGPGAGREAAIRALQAAGLEVTAIKDVTPVPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: RLA1_PENBR
Sequence: MSTAELAVSYAALILADDGIEVSADKIQTILGAAKVQEVEPIWATIFAKALEGKDIKEILTNVGSAGPATAGAPAAAGAAAPAEEKKEEKEEEKEESDEDMGFGLFD
What is the function of this protein?
Plays an important role in the elongation step of protein synthesis.
What are the official names of this protein?
60S acidic ribosomal protein P1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein P1/P2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_FINM2
Sequence: MGKYFGTDGIRGVAGEDLTVELAYKLARAACYKLKDVDNKLIVIGKDTRISGDMLEAALISGITSMGFDVYRLGVIPTPAVAYLTRFYNACCGIVISASHNPYEFNGIKYFSNEGFKLKDSLEEEIEYLIDHQDEIDLKVTGEKVGRVYEEECARDTYINYLLSRVDLDLTGVKVSLDCGYGATSEIAPIIFNRLNADVTVTNTEYDGKNINFKCGSTNPEVISNLVKISESDMGFSFDGDGDRLIACDETGEIMDGDHVICAVGHFLKENNKLKNNAVVGTVMTNIGLIKSLKEIGVDVIKTQVGDRYVLEEMRKNGYIIGGEQSGHIIFIEDNTTGDGILSAIKLAEIAVKSKQKLSEMNNLMTSFPQVLVNAKVNNEYKKVYKDDEVINQKIAELEHEFKDEGRVLIRPSGTEPLIRVMIEGENQEYLEKKAIELKDLIEERCELI
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: Y4850_VIBPA
Sequence: MKKSLFATGLAIAMALPLGAQAADYVIDTKGAHASINFKVSHLGYSFIKGRFNTFSGDFSFDEKNIADSKVNVVVDTTSLDSNHAERDKHIRSGDFIDAGKYSEATFKSTKVVDKGNGKLDVTGDLTLHGVTKPITIEAEFVGAGNDPWGGERAGFVGTTRLELADFDIPVMGSSSYVDMELHIEGVKK
What are the official names of this protein?
UPF0312 protein VPA0850.
What is the protein family that this protein belongs to?
Belongs to the UPF0312 family. Type 1 subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: RECX_LISMO
Sequence: MKITSISVQQKNKERYNIFIDEKYNFSVDEEVLARYQLMKGKVLTEADIEEIKQADMVRKGLNKAINFLSHRVRSEKEIRDYLRKQEMEPFAIDEILKKLANMDYINDFEFAELYTKTQIKTTLKGPRTIERELVEKGLTREIISRVIEEYSDEAQLENATKQAMKIMKRNNKSAKKMLQQKIITDLIQKGFTSELAKAAATEATSELDVADEAEILQKQIEKTMRKNKRYKPSIAKQKTITSLMQKGFSYDTIQSYLTENEISFEEEE
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PVK1_SHELA
Sequence: GASGLIPVMRN
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-1, SheLa-PVK-1.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: IRAP_ECOSM
Sequence: MKNLIAELLFKLAQKEEESKELCAQVEALEIIVTAMLRNMAQNDQQRLIDQVEGALYEVKPDASIPDDDTELLRNYVKKLLKHPRQ
What is the function of this protein?
Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate starvation, but also in stationary phase and during nitrogen starvation.  Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway.
What are the official names of this protein?
Anti-adapter protein IraP.
What is the protein family that this protein belongs to?
Belongs to the IraP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQRD_VIBC3
Sequence: MSSAKELKKSVLAPVLDNNPIALQVLGVCSALAVTTKLETAFVMTLAVMFVTALSNFFVSLIRNHIPNSVRIIVQMAIIASLVIVVDQILKAYLYDISKQLSVFVGLIITNCIVMGRAEAFAMKSEPIPSFIDGIGNGLGYGFVLMTVGFFRELLGSGKLFGLEVLPLISNGGWYQPNGLMLLAPSAFFLIGFMIWAIRTFKPEQVEAKE
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit D, Na(+)-NQR subunit D, Na(+)-translocating NQR subunit D, NQR complex subunit D, NQR-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL27_COREF
Sequence: MATKKGASSSSNGRDSEAKRLGVKRFGGQQVNAGEILVRQRGTKFHPGENVGRGGDDTLFALKTGAVQFSTKRNRRMVNIVENEAVDA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: SWR1_GIBZE
Sequence: MPETASTANVLPKSDPDAIKTEQDALEGYENGGDALQGTMDGHVETNGDAPATENHHEPNHIHDDERPAKRRRTRDSTPPQNTPKKMKPVSPPWKKISADGPTSYTENGRRKSGRINTLLPEPSPLSKSRTSKRSTGANSNTKTEIHLTNGNSRKMPNGSHKASPATKAPSKQAPASTPKSASKKPTETRTSSRSTRRRSPTPPPPPKNSTRSRRSARFSDAVIKDEAVQDSRTATSNSTNRSPRIKLRVGRSGHIPLVHPGQVRKRPKIGTSFEDFWTRAGDIPVEEGGLQASEDGPQYTDELAERDARVILRVEKEVEDGGMLSQGRCSIFLPEPAEEPPRQWARQDHMVKAMTNFRKLMLAEQQRHRIAAKKVAEACRDEWLRRQPKSEEEIEAEQRAVWISRYRIVAKTLFGTWENVRTEVNRRRLAEWEQEEQRRVKAALNEAVNLSEQKLQARQAGLDSEQLSEEDGFDDLSDDMSMADDDELGLASGEDEDDEDGDADSDIMSSDEEEGDEEDQKDIGDENLTQEQLRAKYAHIPELEKPSTETPVTEPTPKDTDAVDTAQATATENAETSDESVDMDDDMGSTDMDSDEEDEEEESEEESDEDAGGLLGLLFGKSELKKMNSEAVAETPADSKEDSEMPDVEAVSDGEGAEENEMSLIQMPDPEPHESGALEKSTKEAVEEKEQIPAAMQDVAAGQDGLSNTDNNVQEPASQDNDVAMTGNDPEEPSALTFEKPHSPATEPATNPPSRVHSTSPPATSETKPSELDTASTEEMAVDKHDTSRSPSPQPSNHKIEVPFLLRGTLREYQRDGLDWLAGLYANSTNGILADEMGLGKTIQTIALLAHLACTHEVWGPHLVIVPTSVMLNWEMEFKKWCPGFKILAYYGSQEERKRKRQGWNNDDIWNVCITSYQLVLQDQQVFKRRRWHYMILDEAHNIKNFKSQRWQTLLGFNTQARLLLTGTPLQNNLTELWSLLFFLMPAENGVGGFADLQEFHDWFAKPESQILESGREQMDDEARAIISKLHKVLRPYLLRRLKADVEKQMPAKYEHVEFCRLSKRQRELYDGFLSRTDTKETLNSGNYLSIINCLMQLRKVCNHPDLFVDRPIMTSFRMQKSVVSDFEVTEQRVQRLLHDPSPMKDVSLGFLNLMPTQCESLSTTQAERISQLSSHRKLMELREAQKIRAQSAHANLDPSTVASNIGYLESGARWGRYEELQHCVYLNALRRQKKPIYGKNLIELLTIGTDKRPYKPRPKIPRQVLAWFEEESTLVQSMIPTVNQRADSFKTIIEKFSCVTPAVVTRDMEQFVLGRKGIEAFSDEDLKLSAPVRWAPFLPKEAPPDPWHEGRMRLSIQFPDKRLLQYDCGKLQILDKLLRKLQAGGHRALIFTQMTKVLDILEQFLNIHGHKYLRLDGATKVEQRQILTDRFNNDPRILCFILSTRSGGLGINLTGADTVIFYDQDWNPAMDKQCQDRCHRIGQTRDVHIYRLVSEHTIEANILRKASQKQMLDDVVIQEGEFTTDYFNKLSVRDVLSEKLDSKSEGLDAADAALDRVLGGPDTNNDQRRVGRALEQAEDREDVAAARVAEKEIQADDADFTEKPSNNASGTSTARQGTPAGKSVLDGGLDDIDAPHVEEVLEYNAWGDKMHTIDDYMLGIMAEQLKDTKLELPKDKKKGKKKGKDTRKR
What is the function of this protein?
Catalytic component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling.
What are the official names of this protein?
Helicase SWR1.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: HEM1_CORGB
Sequence: MSVLIVGMSHRSAPVSLLERLSMDDSVRGETTQALLGRASLSEALIVSTCNRLEVYTVTSSFHTGVNDVVEVLHEASGVDIETLRGYLYVRYADAAAEHMLVVTSGLDSMVLGEQQIIGQVRTAYQAANEYGSVGPALHSLTQTALHTGKRVHSETAIDDAGASMVSFAVDRALVQMGLDSEAEAPLSGKTALVLGAGAMSSLAATHLGRAGISKLIMANRTLERAERLAEHSLEAGVPAEVVEYDQRASAYNRVDLVVSATGADDFTVKPEDIPEGASLMLVDLSMPRDIDDACADLPGVDLVNIERLHKASREGGSGMAPSEEEALAIVREELDSFTSEQRIRDIVPAVSALRRQAASVGSDELDRLRQRAPGISEVEWGEVEKTVRRVVDKLLHQPTVRVKELAARSGSISYDSALQELFGLESLASTAAPATTSVNASELPDAGIVAFVNAPSATQTRE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: YE1M_HERAU
Sequence: SMPPQVMVEINGMLNDGCTAFHEAKQVVEGNTIKIEVTTIRPKDAMCTQEISPFSTTIQVDAQLQPGEYTILVNDVAEALKL
What is the function of this protein?
Could be a silencing control element for the regulation of the restriction system.
What are the official names of this protein?
Uncharacterized 10.2 kDa protein in HgiEIM 5'region, ORF11, ORFC.
Protein: CP51_MYCTO
Sequence: MSAVALPRVSGGHDEHGHLEEFRTDPIGLMQRVRDECGDVGTFQLAGKQVVLLSGSHANEFFFRAGDDDLDQAKAYPFMTPIFGEGVVFDASPERRKEMLHNAALRGEQMKGHAATIEDQVRRMIADWGEAGEIDLLDFFAELTIYTSSACLIGKKFRDQLDGRFAKLYHELERGTDPLAYVDPYLPIESFRRRDEARNGLVALVADIMNGRIANPPTDKSDRDMLDVLIAVKAETGTPRFSADEITGMFISMMFAGHHTSSGTASWTLIELMRHRDAYAAVIDELDELYGDGRSVSFHALRQIPQLENVLKETLRLHPPLIILMRVAKGEFEVQGHRIHEGDLVAASPAISNRIPEDFPDPHDFVPARYEQPRQEDLLNRWTWIPFGAGRHRCVGAAFAIMQIKAIFSVLLREYEFEMAQPPESYRNDHSKMVVQLAQPACVRYRRRTGV
What is the function of this protein?
Sterol 14alpha-demethylase whose physiological substrate is not known.  Accepts electrons from the iron-sulfur ferredoxin Fdx encoded by an adjacent gene.  In vitro, catalyzes C14-demethylation of lanosterol, 24,25-dihydrolanosterol and obtusifoliol, to produce the 8,14-dienes stereoselectively.
What are the official names of this protein?
Sterol 14alpha-demethylase, CYPLI, Cytochrome P450 51, Cytochrome P450-14DM, Cytochrome P450-LIA1, Sterol 14-alpha demethylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYK_SYNPW
Sequence: MSDLRETRLEKVSALRDQGREPYALTFDPSDRMARLQSDHADLPKGEERDCAVAVAGRVMTRRVMGKLAFFTLADETGTIQLFLEKAALGEAFAQITSLVDAGDLIGVRGTLRRTDRGELSVKVAEWTMLTKSLQPLPDKWHGLADVEKRYRQRYLDLIVTPQSRETFRRRALTVSAIRRWLDEREFLEIETPVLQSEAGGADARPFITHHNTLDLPLYLRIATELHLKRLVVGGFERVYELGRIFRNEGVSTRHNPEFTSVEVYQAYADYLGMIELTESMIASVCEQVCGGTRLTYQGTEIDLTPPWRRATMHELVEEATGLDFTAFADRAAAAEAMTAKGLPVPDKADSVGRLLNEAFEHAVEANLIQPTFVLDYPEEISPLARKHRSKPGLVERFELFIVGRETANAFSELIDPVDQRGRLEAQQARRAAGDEEAQGVDEDFLQALEVGMPPTGGLGIGIDRLVMLLTDSPSIRDVIAFPLLRPEG
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSHR_HORSE
Sequence: MPLQGPQRRLLGSLNSTLPATPYLGLTTNQTEPPCLEVSIPDGLFLSLGLVSLVENVLVVTAIAKNRNLHSPMYYFICCLAVSDLLVSMSNVLEMAILLLLEAGVLATQASVLQQLDNIIDVLICGSMVSSLCFLGSIAVDRYISIFYALRYHSIMMLPRVWRAIVAIWVVSVLSSTLFIAYYNHTAVLLCLVTFFVAMLVLMAVLYVHMLARACQHARGIARLHKRQHPIHQGFGLKGAATLTILLGVFFLCWGPFFLHLSLLILCPQHPTCGCVFKNFKLFLTLILCSAIVDPLIYAFRSQELRKTLQEVLLCSW
What is the function of this protein?
Receptor for MSH (alpha, beta and gamma) and ACTH (By similarity).  The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity).  Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes (By similarity).
What are the official names of this protein?
Melanocyte-stimulating hormone receptor, MSH-R, Melanocortin receptor 1, MC1-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL34_SHEDO
Sequence: MSKRTFQPSNLKRKRSHGFRARMATVGGRKVLARRRAKGRARLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: RNPC3_HUMAN
Sequence: MAAPEQPLAISRGCTSSSSLSPPRGDRTLLVRHLPAELTAEEKEDLLKYFGAQSVRVLSDKGRLKHTAFATFPNEKAAIKALTRLHQLKLLGHTLVVEFAKEQDRVHSPCPTSGSEKKKRSDDPVEDDKEKKELGYLTVENGIAPNHGLTFPLNSCLKYMYPPPSSTILANIVNALASVPKFYVQVLHLMNKMNLPTPFGPITARPPMYEDYMPLHAPLPPTSPQPPEEPPLPDEDEELSSEESEYESTDDEDRQRMNKLMELANLQPKRPKTIKQRHVRKKRKIKDMLNTPLCPSHSSLHPVLLPSDVFDQPQPVGNKRIEFHISTDMPAAFKKDLEKEQNCEEKNHDLPATEVDASNIGFGKIFPKPNLDITEEIKEDSDEMPSECISRRELEKGRISREEMETLSVFRSYEPGEPNCRIYVKNLAKHVQEKDLKYIFGRYVDFSSETQRIMFDIRLMKEGRMKGQAFIGLPNEKAAAKALKEANGYVLFGKPMVVQFARSARPKQDPKEGKRKC
What is the function of this protein?
Participates in pre-mRNA U12-dependent splicing, performed by the minor spliceosome which removes U12-type introns.  U12-type introns comprises less than 1% of all non-coding sequences.  Binds to the 3'-stem-loop of m(7)G-capped U12 snRNA.
What are the official names of this protein?
RNA-binding region-containing protein 3, RNA-binding motif protein 40, RNA-binding protein 40, U11/U12 small nuclear ribonucleoprotein 65 kDa protein, U11/U12 snRNP 65 kDa protein, U11/U12-65K.
What are the subcellular locations of this protein?
Nucleus.
Protein: YD355_YEAST
Sequence: MLALISGKLSSNCEASLNSLVESIVSSMLLLCLFLTGPSFSSPLLAFGTLVGDTTCVCVVFRLDLINPTGVNSMFFKLPFGRCDASSMSVYQPFFALCGL
What are the official names of this protein?
Putative uncharacterized protein YDR355C.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.