PharMolix/UniProtQA huggingface dataset:
Protein: ICAA_STAAS
Sequence: MQFFNFLLFYPVFMSIYWIVGSIYFYFTREIRYSLNKKPDINVDELEGITFLLACYNESDTIEDTLSNVLALKYEKKEIIIINDGSSDNTAELIYKIKENNDFIFVDLQENRGKANALNQGIKQASYDYVMCLDADTIVDQDAPYYMIENFKHDPKLGAVTGNPRIRNKSSILGKIQTIEYASLIGCIKRSQTLAGAVNTISGVFTLFKKSAVVDVGYWDTDMITEDIAVSWKLHLRGYRIKYEPLAMCWMLVPETLGGLWKQRVRWAQGGHEVLLRDFFSTMKTKRFPLYILMFEQIISILWVYIVLLYLGYLFITANFLDYTFMTYSFSIFLLSSFTMTFINVIQFTVALFIDSRYEKKNMAGLIFVSWYPTVYWIINAAVVLVAFPKALKRKKGGYATWSSPDRGNTQR
What is the function of this protein?
N-acetylglucosaminyltransferase that catalyzes the polymerization of single monomer units of UDP-N-acetylglucosamine to produce the linear homomer poly-beta-1,6-N-acetyl-D-glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide.  Requires IcaD for full activity (By similarity).
What are the official names of this protein?
Poly-beta-1,6-N-acetyl-D-glucosamine synthase, PNAG synthase, Poly-beta-1,6-GlcNAc synthase, Biofilm polysaccharide intercellular adhesin synthesis protein IcaA, Biofilm PIA synthesis protein IcaA, Intercellular adhesion protein A, N-acetylglucosaminyltransferase IcaA.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TIG_VIBA3
Sequence: MQVTVETLEGLERRLNITVPAANIEDAVTAELRNIAKNRRFDGFRKGKVPMKMVAKMYGKAVRQDVMGEVMQRHFIEAIVKEKINPAGAPTFAPVENNEGADLVFNATFEVYPEVELKGLENITVEKPAVEVKEADVEEMIETLRKQQATWTEVEAAADAGSRATIDFVGSIDGEEFEGGKAENFPLEMGAGRMIPGFEDGIVGKTAGMEFEIEVNFPEDYHAENLKGKAAKFSIKLNKVEARELPELNEEFVSKFGAAEGVEGLKAEVRKNMERELKQAVKNRIKEQAIDGLVNENNIDVPSALIDQEIGVLRQQAAQRFGGNTEAADQLPRELFEEQAKRRVVVGLLLGEVIKTEELKADDEKVKAIIEEMATAYEDPTEVIAYYEQNEQMMNNMRNVALEEQAIDAIIAKAQVSDKEVSFNELMNQQPA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: RS17_PORG3
Sequence: MERNLRKERVGVVSSNKMDKTITVAVKWKEKHPIYGKFVNKTKKYHAHDEKNECGIGDTVRIMETRPLSRTKRWRLTEIIERAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: UNC51_CAEEL
Sequence: MEQFDGFEYSKRDLLGHGAFAIVYRGRYVDRTDVPVAIKAIAKKNISKSKNLLTKEIKILKELSSLKHENLVGLLKCTETPTHVYLVMEFCNGGDLADYLQQKTTLNEDTIQHFVVQIAHALEAINKKGIVHRDLKPQNILLCNNSRTQNPHFTDIVIKLADFGFARFLNDGVMAATLCGSPMYMAPEVIMSMQYDAKADLWSIGTILFQCLTGKAPFVAQTPPQLKAYYEKTRELRPNIPEWCSPNLRDLLLRLLKRNAKDRISFEDFFNHPFLTSPLLPSPSKRILESARSPLLANRRIITPQSSLPVPKRAGSTKLDSPTPVRRIGESPRVQRRVITPGMPSPVPGAPMQESTDFTFLPPRQESSPVKQVQVHTNVSPSLTTCKPVPVPSQRLTYQKMEERLAAARKTAVPSSSSPTGSAVSAQHQHQHQQQQEPASSPVVQRIERPDQLPRRTTLQDPNAHDIERMTMPNPTFVVCGSSTKPSPNNANRVRRSTITSPADTQDMVAADQMLSNLDPTTTTTTIPKSATTANIQGIPRGARDRSVTSPPQPTIHENEPLDNAKYQQTDVNNSPTAPTEPFIIKNQTTCSTSSTSSSVVEEEEAMSLPFASGSHLAAGFKKTPAEVPMDHGALPPALDQEIVLGEEHKQILAKLRFVAELVDTLIHVAEQKDNPLASAMASRRQLLTTGTSTTNTSSPYRRAEQLVVYVRALHMLSSALLLAQTNVANRVLHPSVAVQQVLNQLNDKYHQCLVRSQELASLGLPGQDPAMAVISAERIMYRHAIELCQAAALDELFGNPQLCSQRYQTAYMMLHTLAEQVNCDQDKTVLTRYKVAVEKRLRILERQGFVAAVNT
What is the function of this protein?
Protein kinase important for axonal elongation and axonal guidance (PubMed:7958904, PubMed:15539493).  Functions in the CAN axons to direct both anterior and posterior migrations (PubMed:15539493).  Phosphorylates both unc-14 and vab-8 (PubMed:15539493).  Component of the unc-51/atg-13 complex that is probably recruited by lgg-1 to preautophagosomes and is required for autophagosome formation (PubMed:12958363, PubMed:17890369, PubMed:19377305, PubMed:26687600).  Interaction with autophagy related proteins such as atg-13 links it to the autophagy machinery to in turn promote P-granule degradation in somatic cells (PubMed:19377305).  Plays a role in mitophagy during limited food availability (PubMed:30133321).  Regulates cell size (PubMed:17890369).  Plays a role in male tail ray pattern formation (PubMed:17890369).  May be required for normal dauer morphogenesis (PubMed:12958363).
What are the official names of this protein?
Serine/threonine-protein kinase unc-51, Uncoordinated protein 51.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.
Protein: AROQ_BUCCC
Sequence: MKKKINILLINGPNLNLLGTREPEIYGKKTLEQIVNKIKKKSILLNVTLYDFQSNAEHKIVEKIHNCKKNNIQFILINPGAFTHTSISIRDALSAINIPFFEIHISNIFARENFRSHSWMSDIAQGVISGFGNYGYQIALKTAVKFLLEKEK
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: ECM21_YEAST
Sequence: MPFITSRPVAKNSSHSLSETDLNQSKGQPFQPSPTKKLGSMQQRRRSSTIRHALSSLLGGANVHSPAVLNNTTKGGNNNGNIRSSNTDAQLLGKKQNKQPPPNARRHSTTAIQGSISDSATTTPRSSTSDTNRRTSGRLSVDQEPRISGGRYSQIEEDSTVLDFDDDHNSSAVVSSDLSSTSLTRLANSKKFNEQFLIEYLTARGLLGPKTVLSNEYLKISISTSGESVFLPTISSNDDEYLSRLNGLNDGTDDAEADFFMDGIDQQEGNTPSLATTAAATESGGSINENRDTLLRENNSGDHPGSGSELNTRSVEIDSSMVSYSIAVIVSVKKPTRFTDMQLELCSRVKVFWNTGVPPTKTFNEEFYNAASMKWNLNDENFDLFVPLSISPDDQMIENNSNDRQMRLFKNIPTEERLYLDKTKTKASLLNAIDVNKTHLYQPGDYVFLVPVVFSNHIPETIYLPSARVSYRLRLATKAINRKGFYRQDSNSPQPIVSPDSSSSLSSTTSSLKLTETESAQAHRRISNTLFSKVKNHLHMSSHQLKNEESGEEDIFAEYPIKVIRTPPPVAVSTANKPIYINRVWTDSLSYEISFAQKYVSLNSEVPIKIKLAPICKNVCVKRIHVSITERVTFVSKGYEYEYDQTDPVAKDPYNPYYLDFASKRRKERSVSLFEIRTKEKGTRALREEIVENSFNDNLLSYSPFDDDSDSKGNPKERLGITEPIIIETKLKFPKYEDLDKRTAKIIPPYGIDAYTSIPNPEHAVANGPSHRRPSVIGFLSGHKGSKSHEENEKPVYDPKFHQTIIKSNSGLPVKTHTRLNTPKRGLYLDSLHFSNVYCRHKLEIMLRISKPDPECPSKLRHYEVLIDTPIFLVSEQCNSGNMELPTYDMATMEGKGNQVPLSMNSDFFGNTCPPPPTFEEAISVPASPIVSPMGSPNIMASYDPDLLSIQQLNLSRTTSVSGPSGYSDDAGVPNVNRNSISNANAMNGSISNSAFVSGNSGQGVARARATSVNDRSRFNNLDKLLSTPSPVNRSHNSSPTNGLSQANGTVRIPNATTENSKDKQNEFFKKGYTLANVKDDEEQEGIVSSSSADSLLSHGNEPPRYDEIVPLMSDEE
What is the function of this protein?
May be involved in cell wall organization and biogenesis.
What are the official names of this protein?
Protein ECM21, Extracellular mutant protein 21.
What is the protein family that this protein belongs to?
Belongs to the CSR2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPH_MORIN
Sequence: MNPLISAASVIAAGLAVGLASIGPGVGQGTAAGQAVEGIARQPEAEGKIRGTLLLSLAFMEALTIYGLVVALALLFANPFV
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, chloroplastic, ATP synthase F(0) sector subunit c, ATPase subunit III, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: AIM32_ZYGRC
Sequence: MVFHYRSILKYQVFRAYFHRQYEQVRIHTGGSQLLTCDCQNYSSRLNQSLPNEFKLDVDSPLPSKVPSYKKHALVLSLQNKSADELEWMTNWQSKLELNPMWPYSIIGDLKTHLKHTKFGSDVLVNAISIHSGNLSAPSRDPHERAHIFVIPDMKLYKISPQDVVSFAHFLGGGHTRQVADHQLSFADFLKGADNVVNKTELVSEPSNADHAFPHEDCKRDWILVCGHNQRDRRCGILGKELINEISAKGLDKDKNVALISHVGGHKFAGNLILYNYVGTNEKTGENQLDSLWFSRVLPPNLGTLLEHVDAKKIPQEYYRGGTSMN
What are the official names of this protein?
Altered inheritance of mitochondria protein 32.
What is the protein family that this protein belongs to?
Belongs to the AIM32 family.
Protein: RSMH_STRPJ
Sequence: MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSKLSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLRETGVQEIDGICYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNNYDYHDLVRIFFKYGEDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEVNDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPDDLKPKMELVSRKPILPSAEELEANNRSHSAKLRVVRKIHK
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK22_SPIOL
Sequence: MGFFKKKEKKAEFDVFRLYGLHHPEPGKCDEITTRGYSISMSVDKARRVIDQIRGRSYAETLMILELMPYRACYPIFKLIYSAAANASHNKQFNKANLIISKAEVNKGITLKKVKPRARGRSYMIKRPTCHITIVLRDITHFDSYDKFLESLTPKKLIALLGLMSTGRRRELLCGRFRENHKIKSFLYKIALFKRYEVM
What is the function of this protein?
Component of the chloroplast ribosome (chloro-ribosome), a dedicated translation machinery responsible for the synthesis of chloroplast genome-encoded proteins, including proteins of the transcription and translation machinery and components of the photosynthetic apparatus.
What are the official names of this protein?
50S ribosomal protein L22, chloroplastic, Chloroplastic large ribosomal subunit protein uL22c, Ribosomal protein CS-L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NUOH_ECOSM
Sequence: MSWISPELIEILLTILKAVVILLVVVTCGAFMSFGERRLLGLFQNRYGPNRVGWGGSLQLVADMIKMFFKEDWIPKFSDRVIFTLAPMIAFTSLLLAFAIVPVSPGWVVADLNIGILFFLMMAGLAVYAVLFAGWSSNNKYSLLGAMRASAQTLSYEVFLGLSLMGVVAQAGSFNMTDIVNSQAHVWNVIPQFFGFITFAIAGVAVCHRHPFDQPEAEQELADGYHIEYSGMKFGLFFVGEYIGIVTISALMVTLFFGGWQGPLLPPFIWFALKTAFFMMMFILIRASLPRPRYDQVMSFGWKICLPLTLINLLVTAAVILWQAQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSBY_CYAPA
Sequence: MSMRLVVVLLPLGIALGWAVYNIGKLAIEQWRRTGSKV
What is the function of this protein?
Manganese-binding polypeptide with L-arginine metabolizing enzyme activity.  Component of the core of photosystem II.
What are the official names of this protein?
Photosystem II protein Y.
What is the protein family that this protein belongs to?
Belongs to the PsbY family.
What are the subcellular locations of this protein?
Plastid, cyanelle thylakoid membrane; Single-pass membrane protein.
Protein: DBH_XYLFT
Sequence: MNKTELIDGVAAAANLSKVEAGRAIDAVVNEITEALKEGDSVTLVGFGTFQVRQRAERPGRNPKTGEPIMIAASNNPSFKPGKALKDAVKSSAG
What is the function of this protein?
Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
What are the official names of this protein?
DNA-binding protein HU.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: YJFB_BACSU
Sequence: MDIPALSVAMHQASLAQNVNIALTKKRLDTAQQNADQTLKMIQHPTLGQTIDVKA
What are the official names of this protein?
Uncharacterized protein YjfB.
Protein: PUR9_ACET2
Sequence: MIKRALISVSDKTGIVEMARELQSMGVDIISTGGTAKTLSDAGIKVINISDVTGFPECLDGRVKTLHPKVHAGILAIRSNEEHMRQLKELNIETIDMVIINLYPFKQTILKENVDLSEAIENIDIGGPTMIRAAAKNYQDVVVIVDPSDYAAVLEELKTTKDVSLKTKFKLAYKVFEHTSHYDTLIAKYLREQIGEDEFPQTLSLTFEKVQDMRYGENPHQKAVFYKEVGANVGCITAAKQLHGKELSYNNINDANGAIEIIKEFDEPTVVAVKHANPCGVASASNIYDAYIKAYEADPVSIFGGIIAANREIDEKTAEEINKIFVEIVIAPSFTEGALKILTQKKNIRLLQLEDISAKIPKGTYDMKKVPGGLLVQNYNSELLNMDDLKVVTEKKPTQEELEDLIFAMKVVKHTKSNGIALAKGKQTIGVGPGQTNRVTACKIAIEYGGERTKGAVLASDAFFPFADCVEAAAAAGITAIIQPGGSIRDQESIDACNKYGIAMVFTGMRHFKH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: HDD1_SCHPO
Sequence: MNAAKSLSIVPFLDCLSRLKTTPRTGWLYHGIEKPESIADHMYRMGILTMLCNDPSINKERCLKIAVVHDMAESIVGDITPHENVSKEEKHRMESEAMVSITQQLIPLNLSLQAEEIKELFLEYESASTPEAKFVKDIDKFEMIAQMFEYERKFNGEKDLSQFTWAGKLIQHPLVKGWLNDVLQEREQFWASVRQKKL
What is the function of this protein?
Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
What are the official names of this protein?
5'-deoxynucleotidase hdd1.
What is the protein family that this protein belongs to?
Belongs to the HDDC2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GANP_BACSU
Sequence: MQHRQVALLLSIIPGLGQFYNKQWIKGIVFLFLGASFFAVFGDLLNMGFWGIFTLGTEVPRDNSVFLLAEGIIAVIVTCFGLAVYYVNLRDAFQSGKQRDENKPLSSLKEQYQHIISEGYPYVVSGPSLFILIFAVIFPILFSFALAFTNYDLYHSPPAKLIDWVGFQTFANIFTVDIWRSTFFDVLAWTVVWTLAASTLQVTLGIFLAIIVNQKDLRFKRFFRTILILPWAVPGFVTILIFAGLFNDSFGAMNHDILAFFGIDPLPWMTDANWSRLALILMQGWLGFPYIFLVSTGVLQSIPDDLYEAATIDGASVFSKLRYITLPMVFIAMAPIIITQFTFNFNNFNIIYLFNGGGPAVTGSTAGGTDILVSWIYKLTMQSSQYSLAAALTILLSVFVISIALWQFRQTKSFKEEA
What is the function of this protein?
Involved in galactan degradation (PubMed:27501980).  Part of the ABC transporter complex GanPQS involved in the uptake of galactooligosaccharides (PubMed:27501980, PubMed:29240795).  Responsible for the translocation of the substrate across the membrane (Probable).
What are the official names of this protein?
Galactooligosaccharides transport system permease protein GanP.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EFP_MYCGI
Sequence: MASTADFKNGLVLQIDGQLWQIVEFQHVKPGKGPAFVRTKLKNVVSGKVVDKTYNAGVKVETATVDRRDATYLYRDGSDFVFMDSEDFEQHPLPEALVGRLAGFLLESMPVQIAFHDGVPLYLELPVTVELLVAHTEPGLQGDRSSAGTKPATMETGAEIQVPLFINTGDKLKVDSRDGSYLGRVNA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MILK2_HUMAN
Sequence: MAAIRALQQWCRQQCEGYRDVNICNMTTSFRDGLAFCAILHRHRPDLINFSALKKENIYENNKLAFRVAEEHLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYFHGRSPIGGMAGVKRASEDSEEEPSGKKAPVQAAKLPSPAPARKPPLSPAQTNPVVQRRNEGAGGPPPKTDQALAGSLVSSTCGVCGKHVHLVQRHLADGRLYHRSCFRCKQCSCTLHSGAYKATGEPGTFVCTSHLPAAASASPKLTGLVPRQPGAMGVDSRTSCSPQKAQEANKARPSAWEPAAGNSPARASVPAAPNPAATSATSVHVRSPARPSESRLAPTPTEGKVRPRVTNSSPMGWSSAAPCTAAAASHPAVPPSAPDPRPATPQGGGAPRVAAPQTTLSSSSTSAATVDPPAWTPSASRTQQARNKFFQTSAVPPGTSLSGRGPTPSLVLSKDSSKEQARNFLKQALSALEEAGAPAPGRPSPATAAVPSSQPKTEAPQASPLAKPLQSSSPRVLGLPSRMEPPAPLSTSSTSQASALPPAGRRNLAESSGVGRVGAGSRPKPEAPMAKGKSTTLTQDMSTSLQEGQEDGPAGWRANLKPVDRRSPAERTLKPKEPRALAEPRAGEAPRKVSGSFAGSVHITLTPVRPDRTPRPASPGPSLPARSPSPPRRRRLAVPASLDVCDNWLRPEPPGQEARVQSWKEEEKKPHLQGKPGRPLSPANVPALPGETVTSPVRLHPDYLSPEEIQRQLQDIERRLDALELRGVELEKRLRAAEGDDAEDSLMVDWFWLIHEKQLLLRQESELMYKSKAQRLEEQQLDIEGELRRLMAKPEALKSLQERRREQELLEQYVSTVNDRSDIVDSLDEDRLREQEEDQMLRDMIEKLGLQRKKSKFRLSKIWSPKSKSSPSQ
What is the function of this protein?
Effector of small Rab GTPases which is involved in junctional complexes assembly through the regulation of cell adhesion molecules transport to the plasma membrane and actin cytoskeleton reorganization.  Regulates the endocytic recycling of occludins, claudins and E-cadherin to the plasma membrane and may thereby regulate the establishment of tight junctions and adherens junctions.  In parallel, may regulate actin cytoskeleton reorganization directly through interaction with F-actin or indirectly through actinins and filamins.  Most probably involved in the processes of epithelial cell differentiation, cell spreading and neurite outgrowth (By similarity).
What are the official names of this protein?
MICAL-like protein 2, Junctional Rab13-binding protein, Molecule interacting with CasL-like 2, MICAL-L2.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Cell junction, tight junction. Recycling endosome. Cell projection. Cytoplasm, cytoskeleton. Cytoplasm, cytosol.
Protein: Y1069_THEYD
Sequence: MSKKMFGEIMRQAQKIQEEIQKKQEEVKKMTVEATSGGGMVTVQANGAGEIVSIKIDREVVNPDDIEMLEDLVLAAVNEAIKRAHELAQSEMAKVSMPFNLPGMPDLSSLFGKL
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein THEYE_A1069.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: DUT_BEII9
Sequence: MTMPPPRPPRILVKRLAHAEGLALPAYQTAGAAGLDLAAALPHGTTLVLEPGGRHLLPTGFCLEIPEGYEAQVRPRSGLARKHGVTVLNTPGTIDADYRGEIGVILINMGDEPFEIVRGTRIAQLVVAPCVQAELIETHTLSDTERGEDGFGSTGHGSHQ
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: RL15_ACHLI
Sequence: MILSNLKPVPGARHSKKRLGRGPGSGTGKTSGKGHKGQKARSGGGVRPGFEGGQIPFFQRIPKRGFNNHTRVEYAIVNTKELNVFEDGTVVTPELLLQTKLVSKVLAGVKILADGKLEKKLTVKANKFSNSAKEAIEAAGGTIEVI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: HFQ_BRUSI
Sequence: MAERSQNLQDLFLNSVRKQKISLTIFLINGVKLTGIVTSFDNFCVLLRRDGHSQLVYKHAISTIMPSQPVQMFEGEEA
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: LST2_ANOGA
Sequence: MVTTIVIACTFRAGTTHHSWCAAVALRAGSFAADDKSLLARFYHADRALTAIASELDSFDGRAEPVRCTRLVSRLRQGQDRVLAITNQIMDELLGDDRAQRAFRVKFPEEVLQESLAGQLWFGAECLAAGSSILNREAESAKMRPLAKAVTKSLEIVRNRLREQCLRNNTPNSPTLRLDINDAATEQLYESLKIFDRLFAEFELVYVSAMVQVKTKQEYEMQELICVLFSETLQRALKTGLLEQEQVDSYDPALMFSIPRLAIIAGLVIFREGPLNMDQPADNISEMFRPFRKLLIKMRDLLHALTKQELYQLEKLLCTNEEISASEQLICDEKGRSGGDGGSGSGGTAAAGVKEFDALEPVGESQEHVVIVTTVTTTNAPNVVGDGPGATGCTDATSGADGRLHIVSQGYGVSTGATGSSGFGSGRGGCSSSSTSRPKQRHNQAHLRQRGAPRHSSQSFAPEASYAGDDREPVVEEDNNNHLRKEIEEEDVDDDMEEEEEDEEEDEVDDDAMLKDGLVTTDCASGYLIPNTNFGNLLQTNEAPLTDSFIATDDELRLLGAETASSPPAMTQANIDSILAASAAGSGGQQQQQQQQQLIDSDSGHGTANHSTDMSPELETERTVVAAGQPNANDAPLDGSVSKQQPVRDRSRSGSSTVHKHAEISESSSDYEEADVDDEPDDVDADDDDEEEDDVVGEVEEQNDSEPTFNRKVGGAPKEAFRSQLRCKAARNHRKSSHHRPRPSTSSSSSSAAYRNKSQSHQHHHHHHHHHHHSYAESAEGTSSVVSTITTSNNSTSNGSTRHHSRMQQQHQQHQQQRNSSSSCDTSPTQSECSDAQEVALAIRAAGRNKFKSTENLLHRLFVCIAGVADQLQTNFAADLRKMLRSVFIMNSSPPEPDEPPEPSGSEEESKDSQHNHPSDLFEFRASEQDVITADQQNHSGGSSQSIYSAEEANPEQDSVFGSSGDSSPVRRTASVESRNVTVNVSVSVVASSPVGAGGAGGGGMVGGSRTGQERSVSLSEACIVVEGGKASAGGGGGTRRHSASGSKNDYGRSRSSPSSPVNSNTGGGGGGNHHSSAHHTAHEQQRRMPEEPPRWIPDCDAPRCMACASAFTPFRRRHHCRNCGGVFCGVCSNLSKPLPKYGLTKAVRVCRDCYIHEVGV
What is the function of this protein?
Negative regulator of epidermal growth factor receptor (EGFR) signaling.
What are the official names of this protein?
Lateral signaling target protein 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the lst-2 family.
Protein: RS19_BURCH
Sequence: MARSVKKGPFCDAHLLKKVEAAAASRDKKPIKTWSRRSTILPDFIGLTIAVHNGRQHVPVYISENMVGHKLGEFALTRTFKGHAADKKAKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: PYRH_FLAPJ
Sequence: MKYKRILLKLSGEALMGDRQYGIDPKRLAEYADEIKQIHDLGVQIAIVIGGGNIFRGIAGASNGMDRVQGDYMGMLATVINGMALQGALEEKGMLTRLQTALKIEAIAEPYIKRRAVRHLEKNRIVIFGAGTGNPYFTTDTAAVLRGVEVDADVILKGTRVDGIYNVDPEKNKDAVKFDNISFEDVLKKGLNVMDTTAFTLSQENKLPIIVFDMNKEGNLLKICKGENIGTVVNI
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_VIBPA
Sequence: MTTNPKPAYQRILLKLSGEALQGEDGFGIDPAILDRMAQEVKELVELGVQVGVVIGGGNLFRGAGLAEAGMNRVVGDHMGMLATVMNGLAMRDALHRAYVNARVMSAIPLKGVCDDYNWADAIRELRQGRVVIFSAGTGNPFFTTDSAACLRGIEIEADVVLKATKVDGVFTADPVANPDAELYDKLSYAEVLDKELKVMDLAAFTLARDHKMPIRVFNMNKPGALRRVVMGEAEGTLINSDA
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOMA_PAGMA
Sequence: MDRVVLMLSVLSLGVSSQPITDGQRLFSIAVSRVQHLHLLAQRLFSDFESSLQTEEQLKLNKIFPDFCNSDYIISPIDKHETQRSSVLKLLSISYRLVESWEFPSRSLSGGSAPRNQISPKLSELKMGIHLLIRANEDGAEIFPDSSALQLAPYGNYYQSLGADESLRRTYELLACFKKDMHKVETYLTVAKCRLSPEANCTL
What is the function of this protein?
Growth hormone plays an important role in growth control and is involved in the regulation of several anabolic processes.  Implicated as an osmoregulatory substance important for seawater adaptation.
What are the official names of this protein?
Somatotropin, Growth hormone.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.