PharMolix/UniProtQA huggingface dataset:
Protein: DMRT1_HUMAN
Sequence: MPNDEAFSKPSTPSEAPHAPGVPPQGRAGGFGKASGALVGAASGSSAGGSSRGGGSGSGASDLGAGSKKSPRLPKCARCRNHGYASPLKGHKRFCMWRDCQCKKCNLIAERQRVMAAQVALRRQQAQEEELGISHPIPLPSAAELLVKRENNGSNPCLMTECSGTSQPPPASVPTTAASEGRMVIQDIPAVTSRGHVENTPDLVSDSTYYSSFYQPSLFPYYNNLYNCPQYSMALAADSASGEVGNPLGGSPVKNSLRGLPGPYVPGQTGNQWQMKNMENRHAMSSQYRMHSYYPPPSYLGQSVPQFFTFEDAPSYPEARASVFSPPSSQDSGLVSLSSSSPISNKSTKAVLECEPASEPSSFTVTPVIEEDE
What is the function of this protein?
Transcription factor that plays a key role in male sex determination and differentiation by controlling testis development and male germ cell proliferation.  Plays a central role in spermatogonia by inhibiting meiosis in undifferentiated spermatogonia and promoting mitosis, leading to spermatogonial development and allowing abundant and continuous production of sperm.  Acts both as a transcription repressor and activator: prevents meiosis by restricting retinoic acid (RA)-dependent transcription and repressing STRA8 expression and promotes spermatogonial development by activating spermatogonial differentiation genes, such as SOHLH1.  Also plays a key role in postnatal sex maintenance by maintaining testis determination and preventing feminization: represses transcription of female promoting genes such as FOXL2 and activates male-specific genes.  May act as a tumor suppressor.  May also play a minor role in oogenesis (By similarity).
What are the official names of this protein?
Doublesex- and mab-3-related transcription factor 1, DM domain expressed in testis protein 1.
What is the protein family that this protein belongs to?
Belongs to the DMRT family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SUN5_HUMAN
Sequence: MPRSSRSPGDPGALLEDVAHNPRPRRIAQRGRNTSRMAEDTSPNMNDNILLPVRNNDQALGLTQCMLGCVSWFTCFACSLRTQAQQVLFNTCRCKLLCQKLMEKTGILLLCAFGFWMFSIHLPSKMKVWQDDSINGPLQSLRLYQEKVRHHSGEIQDLRGSMNQLIAKLQEMEAMSDEQKMAQKIMKMIHGDYIEKPDFALKSIGASIDFEHTSVTYNHEKAHSYWNWIQLWNYAQPPDVILEPNVTPGNCWAFEGDRGQVTIQLAQKVYLSNLTLQHIPKTISLSGSLDTAPKDFVIYGMEGSPKEEVFLGAFQFQPENIIQMFPLQNQPARAFSAVKVKISSNWGNPGFTCLYRVRVHGSVAPPREQPHQNPYPKRD
What is the function of this protein?
Plays an essential role in anchoring sperm head to the tail.  Is responsible for the attachment of the coupling apparatus to the sperm nuclear envelope.
What are the official names of this protein?
SUN domain-containing protein 5, Sad1 and UNC84 domain-containing protein 5, Sperm-associated antigen 4-like protein, Testis and spermatogenesis-related gene 4 protein.
What are the subcellular locations of this protein?
Nucleus inner membrane; Single-pass membrane protein. Golgi apparatus. Note=During spermiogenesis, traffics through the Golgi apparatus before reaching the round spermatid inner membrane of the nuclear envelope and later migrates to the coupling apparatus of the sperm during sperm head elongation and differentiation. In mature spermatozoa, is localized to the coupling apparatus of the sperm head and tail in the implementation fossa.
Protein: ATPA_MYXXD
Sequence: MEIRADEISRIIREQIKDYGKKVTVAETGTVLSVGDGIARIYGLEGALAGELVEFANGVQGLVLNLEEDNVGVAIMGDFQAIREGDTVKRTQQIASVPVGKELLGRVVDPLGKPLDGKGPIAATETRRLEVKAPGIVSRKSVHEPLQTGIKALDALVPVGRGQRELIIGDRQTGKTAVAIDTIINQKGLNVYCIYVAIGQKQSTVAQVVEKLNRYGAMEYTTVVASNASDPAPMQFFAPYAGVAMGEYFRDNKMHALIVYDDLSKQAVAYRQLSLLLRRPPGREAYPGDVFYVHSRLLERAAKLSDEEGAGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLETDLFFAGVRPAINVGLSVSRVGSAAQIKAMKQVAGTMKLELAQYRELAAFAQFGSDLDKATQETLARGARMVELLKQGQYEPMPVEKQVMQIYAATNRDDPKKRGWIRDIPTADVVRWMREFLEFADGKHPNVAKDLASKRELTADIKTALSKAITEFNEVFQPTPGAKV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL19_CAMFF
Sequence: MRNKYIEAFENAQIENKSVPDFRAGDTLRIAIRIKEGDKTRVQNFEGICIARRGSGSGETFIIRKIGANSVGVERIFPIYSESLESITVLRRGRIRRSKLFYLRDRRGKAARIKELKK
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: ALF4_ARATH
Sequence: MVKFAIINTLTVNETWAKLKSFGVMESSIEGSSESTTVTTSPSRRVRELLALCFSSVEEAGGFQDFESFVTELVSCLDSLYENVALDANNELENDVIEEVLDEILKVLSSPQMDQDVIDALSFHLPKVTSKFADISSRCLQLVEEIVDRFVEACNPRDMLSILCEALDAARCYHSASTCSTPLLHGLSKVFILIQRRHYEQLKVAVPIVLNVLKDISLETDVQVEDLFDKALGIASSIRDVSSKLNNEEEAKVRCLLCLYVIQITAIISVSIRDKAASCIPLVIQLEPFLTSCGLTHLGLITGNDTEKLMSTVAGDDDEFITSFPDISLGASLLFICAKISHEVAEAANAVLGSVVDELQNNPVKRWQAYGMLKYILSSGDLLWEFKRHAIEFLLDITKGVTSSQCNDEQIDCSDYTPGIYATLQAVTLLIMYAPDADLRKKTFEALKRVLSDIPAPHRFDVLRALVTNSRSPSMTAILLGLVKDSMSKSSLQDTDCAAVDTHVIELVELVLRPPQGGPPLLPDQSDAILAALNLYRFALLFESRECEAGKERSKVGSDILSKKNLEKAYKEWLLPLRTLVSCSIAENLKEDHGQESSLDDVGLLNPIELVLYRCIELVEEKLKSH
What is the function of this protein?
Required for the initiation of lateral roots independent from auxin signaling.  May function in maintaining the pericycle in the mitotically competent state needed for lateral root formation.
What are the official names of this protein?
Aberrant root formation protein 4.
What are the subcellular locations of this protein?
Nucleus.
Protein: TOP2A_HUMAN
Sequence: MEVSPLQPVNENMQVNKIKKNEDAKKRLSVERIYQKKTQLEHILLRPDTYIGSVELVTQQMWVYDEDVGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVETASREYKKMFKQTWMDNMGRAGEMELKPFNGEDYTCITFQPDLSKFKMQSLDKDIVALMVRRAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDMYLKDKLDETGNSLKVIHEQVNHRWEVCLTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVTKLVDVVKKKNKGGVAVKAHQVKNHMWIFVNALIENPTFDSQTKENMTLQPKSFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQVQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSTECTLILTEGDSAKTLAVSGLGVVGRDKYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKSSTPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDDRKEWLTNFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSSLARLLFPPKDDHTLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREIVNNIRRLMDGEEPLPMLPSYKNFKGTIEELAPNQYVISGEVAILNSTTIEISELPVRTWTQTYKEQVLEPMLNGTEKTPPLITDYREYHTDTTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQRGYDSDPVKAWKEAQQKVPDEEENEESDNEKETEKSDSVTDSGPTFNYLLDMPLWYLTKEKKDELCRLRNEKEQELDTLKRKSPSDLWKEDLATFIEELEAVEAKEKQDEQVGLPGKGGKAKGKKTQMAEVLPSPRGQRVIPRITIEMKAEAEKKNKKKIKNENTEGSPQEDGVELEGLKQRLEKKQKREPGTKTKKQTTLAFKPIKKGKKRNPWSDSESDRSSDESNFDVPPRETEPRRAATKTKFTMDLDSDEDFSDFDEKTDDEDFVPSDASPPKTKTSPKLSNKELKPQKSVVSDLEADDVKGSVPLSSSPPATHFPDETEITNPVPKKNVTVKKTAAKSQSSTSTTGAKKRAAPKGTKRDPALNSGVSQKPDPAKTKNRRKRKPSTSDDSDSNFEKIVSKAVTSKKSKGESDDFHMDFDSAVAPRAKSVRAKKPIKYLEESDEDDLF
What is the function of this protein?
Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand (PubMed:17567603, PubMed:18790802, PubMed:22013166, PubMed:22323612).  May play a role in regulating the period length of BMAL1 transcriptional oscillation (By similarity).
What are the official names of this protein?
DNA topoisomerase 2-alpha, DNA topoisomerase II, alpha isozyme.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleoplasm. Nucleus. Nucleus, nucleolus.
Protein: CD40L_HUMAN
Sequence: MIETYNQTSPRSAATGLPISMKIFMYLLTVFLITQMIGSALFAVYLHRRLDKIEDERNLHEDFVFMKTIQRCNTGERSLSLLNCEEIKSQFEGFVKDIMLNKEETKKENSFEMQKGDQNPQIAAHVISEASSKTTSVLQWAEKGYYTMSNNLVTLENGKQLTVKRQGLYYIYAQVTFCSNREASSQAPFIASLCLKSPGRFERILLRAANTHSSAKPCGQQSIHLGGVFELQPGASVFVNVTDPSQVSHGTGFTSFGLLKL
What is the function of this protein?
Acts as a ligand for integrins, specifically ITGA5:ITGB1 and ITGAV:ITGB3; both integrins and the CD40 receptor are required for activation of CD40-CD40LG signaling, which have cell-type dependent effects, such as B-cell activation, NF-kappa-B signaling and anti-apoptotic signaling.
What are the official names of this protein?
CD40 ligand, CD40-L, T-cell antigen Gp39, TNF-related activation protein, TRAP, Tumor necrosis factor ligand superfamily member 5.
What is the protein family that this protein belongs to?
Belongs to the tumor necrosis factor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Cell surface. SUBCELLULAR LOCATION: [CD40 ligand, soluble form]: Secreted. Note=Release of soluble CD40L from platelets is partially regulated by GP IIb/IIIa, actin polymerization, and a matrix metalloproteinases (MMP) inhibitor-sensitive pathway.
Protein: NA21_HETCR
Sequence: ASCKCDDDGPDVRSATFTGTVDFAYCNAGWEKCLAVYTPVASCCRKKK
What is the function of this protein?
Binds to site 3 of voltage-gated sodium channels and inhibits the inactivation process.
What are the official names of this protein?
Delta-stichotoxin-Hcr1e, Delta-SHTX-Hcr1e, Neurotoxin I, RTX-I, Rm1.
What is the protein family that this protein belongs to?
Belongs to the sea anemone sodium channel inhibitory toxin family. Type II subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: H10_PONAB
Sequence: MTENSTSAPAAKPKRAKASKKSTDHPKYSDMVVAAIQAEKNRAGSSRQSIQKYIKSHYKVGENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKSDEPKKSVAFKKTKKEIKKVATPKKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAKKPKTVKAKPVKASKPKKAKPVKPKAKSSAKRAGKKK
What is the function of this protein?
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.  The histones H1. 0 are found in cells that are in terminal stages of differentiation or that have low rates of cell division (By similarity).
What are the official names of this protein?
Histone H1.0, Histone H1(0).
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: TTCA_YERPB
Sequence: MLEKQSVNQKEQYNFNKLQKRLRRNVGQAIADFNMIEEGDRVMVCLSGGKDSYTMLDILQSLQKSAPINFSLIAVNLDQKQPGFPEDILPAYLDKQGVEYKIVEENTYGIVKEIIPDGKTTCSLCSRLRRGILYRTATELGATKIALGHHRDDILQTLFLNMFYGGKLKGMPPKLMSDDGKHIVIRPLAYCREKDIERFAVAREYPIIPCNLCGSQPNLQRQVIKDMLRDWDKQYPGRIETMFSAMQNVVPSHLNDHKLFDFKSITHDSDIIDGGDLAFDREALPLNPVGWQPEDDEDTEKRPSVRLDVLEIK
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCNB2_ORYCU
Sequence: MSSVEVVAQQQQLLAAEHPRRMGKGAAADPRRAALGELTNLNAVAATNGKVGPSKKPSKASCVQKPKPPQLVAPMIQTGAAASAPVSAKPCVKEEQLCQAFSEVLLAVQDVDEQDADQPQLCSQYVKDIYKYLHVLEEQQPVRANYMQGYEVTERMRALLVDWLVQVHSRFQLLQETLYLTVAILDPFLQVHPVSRRKLQLVGVTAMLVACKYEKMYAPEVGDFSYITDNAFTKSQIVEMEQVILRSLSFQLGRPLPLHFLRRASKVAGADVEKHTLAKYLMELTLLDYHMVHYRPSEVAAAALCLSQLLLDGLPWSLTQQQYSTYEEQHLKPIMQHIAKNVVLVNEGRTKFLAVKKKYSSSKLMKISLIPQLNSSTVKALAESLLNP
What is the function of this protein?
Essential for the control of the cell cycle at the G2/M (mitosis) transition.
What are the official names of this protein?
G2/mitotic-specific cyclin-B2.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
Protein: MATK_ZINOF
Sequence: MEELQGYLEEDRSRQQQFLYPLLFQEYIYVFAYDHGLNSSIFYEPQNSLGYDNKFSSVLVKRLIIRMYQKNYLIYSVNDIYQNIFVGHNNYFYFNFFSQILSEGFAVIVEIPFSLQLISSLEEKEIPKSHNLQSSHSIFPFLEDKLLHLNYLSDILIPYPVHMEILVQILQSWIQDVLSLHLLQFLLHEYYNWNSLIIPKKSIYVFSKENKRLFWFLYNLYIYEYEFLLVFPCKQSSFLRLISSGVLLERIHFYVKIEHLGVYRIFCQKTLWIFKDPFIHYIRYQGKSILGSRGTHFLMKKWKYHLVNFWQYYFHFWSQPYRIDIKKLSNYSFYFLGYFSSVQINSSMVRNQMLENSFLMDTLTKKFDTIIPIIPLIRSLFKAQFCTVSGYPISKPIWTDLADCDIINRFGRICRKLTHYHSGSSKKQSLYRMKYILRLSCARTLARKHKSSARSFLQRLSSGLLEEFFTEEEQVIFLIFPKIISFYLYGSYRERIWYLDIIRINDLVNCLLVTT
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PURR_PECAS
Sequence: MATIKDVAKRAGVSTTTVSHVINKTRFVAEETKAAVRAAIKELHYSPSAVARSLKVNHTKSIGLLATSSEAPYFAEIIEAVENSCYAKGYTLVLCNSHNDIGKQRAYLSMLAQKRVDGLLVMCAEYPPELLGMLEDYRSIPMVVMDWGQMHNDFTDTIIDNAFEGGYMAGRYLIERGHRDIGAIPGIQERNTGSGRYLGFLKALKEADITVRNEWVVQGDFEPESGYKAMHQILAQKQRPTAVFCGGDIMAMGAICAADELGLRVPQDISVIGYDNVRHARFFTPALTTIHQPKERLGQSAFSMLLDRITSKREDAHVIEVHPTLIERRSVADGPFRDYRR
What is the function of this protein?
Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression.  PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.
What are the official names of this protein?
HTH-type transcriptional repressor PurR, Pur regulon repressor, Purine nucleotide synthesis repressor.
Protein: DTD_SHEB5
Sequence: MIALIQRVSRASVVVDNQTIGAIDKGLLVLLGVEQEDTREKMEKLATKVMSYRMFSDENGKMNLNLEQVGGSLLVVSQFTLAADTGRGLRPSFSGAGTPDQALALYEEFVAFCRAKGVTTETGQFGADMQVSLVNDGPVTFNLQV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_CAMJJ
Sequence: MKVRPSVKKMCDKCKVVRRKGVVRIICENPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: VP7_ROTP6
Sequence: MYGIEYSTILTFLISLVFINYLLKSVTRTMDFIIYRFLMIVVLLAPIIKAQNYGINLPITGSMDTPYTNSTMSETFLTSTLCLYYPNEAATEIADTKWKETLSQLLLTKGWPTGSVYFKGYADIASFSVEPQLYCDYNIVLMKYDANLQLDMSELADLILNEWLCNPMDITLYYYQQTDEANKWISMGSSCTIKVCPLNTQTLGIGCSTTDTNSFETVANAEKLVITDVVDGVNHKLDVTTNTCTIRNCKKLGPRENVAVIQVGGSNVLDITADPTTAPQTERMMRVNWKKWWQVFYTIVDYVNQIVQAMSKRSRSLNSAAFYYRV
What is the function of this protein?
Calcium-binding protein that interacts with rotavirus cell receptors once the initial attachment by VP4 has been achieved.  Rotavirus attachment and entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors.  Following entry into the host cell, low intracellular or intravesicular Ca(2+) concentration probably causes the calcium-stabilized VP7 trimers to dissociate from the virion.  This step is probably necessary for the membrane-disrupting entry step and the release of VP4, which is locked onto the virion by VP7.
What are the official names of this protein?
Outer capsid glycoprotein VP7.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP7 family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum lumen. Note=The outer layer contains 780 copies of VP7, grouped as 260 trimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple-layered particles.
Protein: Y094_ANADE
Sequence: MPSFDVVSEVDLMEVENAFNQARKEIAQRFDFKGTHTELERDKEQNVLIRAGSEGRAEAALQVLMEKLAKRGVALESLDPQKLEPASGGHVRQLVKLKRGLKVEDARKIVAKVKESGIKVQAAIQGEAVRVTGKKRDDLQAAIHAIRAAGFPIPLQFQNFRE
What are the official names of this protein?
UPF0234 protein Adeh_0094.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: GSHB_BRADU
Sequence: MKLNVAVQMDPIARINIKGDSTFALLLEAQKRGHGLSYYTPDKLSMIGEELVAPVQLLTVRDEPGDHFTLGEPKREALNGFDVVLLRQDPPFDLAYITSTHFLERIHPKTLVVNDPASVRNAPEKLFVMNFPQLMPPTLISRDLDEINAFRDKHGAVVMKPLHGHGGAAVFRVMPQDMNFGSLFDMFTVTFKEPWVIQQFIPEVKHGDKRIILVNGEFAGAVNRVPAADDLRSNMVRGGAAQETELTPREREICATVGPALRERGLLFVGIDVINGNLTEINVTSPTGIRAIARLGGPDVAAKVWDTIEQKRAK
What are the official names of this protein?
Glutathione synthetase, GSH synthetase, GSH-S, GSHase, Glutathione synthase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic GSH synthase family.
Protein: CMOA_VIBC3
Sequence: MRSAMNPKDTLFSAPIDKIGDFTFDERVAEVFPDMIQRSVPGYSNIISAIGMLAERFVKPHSKIYDLGCSLGAATLSMRRHIKQEGCQIIAVDNSAAMVERCKLHLNAYRSDTPVQVIEADIRDIAIENASVVVLNFTLQFLAPDDRYALLEKIYAGLRPGGILILSEKFVFSDQEAHELLIDLHHDFKRANGYSELEISQKRSAIENVMRPDSIQTHKQRFATLGFSSFEVWFQCFNFGSMFAIK
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: CYB_RABIT
Sequence: MTNIRKTHPLLKIVNHSLIDLPAPSNISAWWNFGSLLGLCLMIQIFTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLYMHVGRGIYYGSYTYLETWNIGIILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIIATLVLIHLLFLHETGSNNPTGIPSNSDKIPFHPYYTIKDTLGFLVAILLLLILVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILVLAFIPFLHMSKQRSMMFRPISQVLFWVLVADLLTLTWIGGQPVEHPFITIGQVASVLYFTTILILMPLASLIENKILKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SSPP_BACCN
Sequence: MEKNNSKSIRQNSKKGQPSGQPEPLSGSHKVKNRNHSRQKHHAHHDM
What are the official names of this protein?
Small, acid-soluble spore protein P, SASP P.
What is the protein family that this protein belongs to?
Belongs to the SspP family.
What are the subcellular locations of this protein?
Spore core.
Protein: HLDD_VIBPA
Sequence: MIIVTGGAGMIGSNIVKALNEAGINDILVVDNLKNGKKFKNLVDLDITDYMDRDDFLTQIMAGDDFGPIEAIFHEGACSATTEWDGKYMMLNNYEYSKELLHYCLDREIPFLYASSAATYGETETFVEEREYEGALNVYGYSKQQFDNYVRRLWKDAEEHGEQLSQITGFRYFNVYGPREDHKGSMASVAFHLNNQINAGENPKLFEGSGHFKRDFVYVGDVCKVNLWFLENGVSGIFNCGTGRAESFEEVAKAVVKHHNKGEIQTIPFPDHLKGAYQEFTQADLTKLRAAGCDVEFKTVAEGVAEYLTIQNS
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: YOXD_BACSU
Sequence: MQSLQHKTALITGGGRGIGRATALALAKEGVNIGLIGRTSANVEKVAEEVKALGVKAAFAAADVKDADQVNQAVAQVKEQLGDIDILINNAGISKFGGFLDLSADEWENIIQVNLMGVYHVTRAVLPEMIERKAGDIINISSTAGQRGAAVTSAYSASKFAVLGLTESLMQEVRKHNIRVSALTPSTVASDMSIELNLTDGNPEKVMQPEDLAEYMVAQLKLDPRIFIKTAGLWSTNP
What are the official names of this protein?
Uncharacterized oxidoreductase YoxD.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: RPB7_YEAST
Sequence: MFFIKDLSLNITLHPSFFGPRMKQYLKTKLLEEVEGSCTGKFGYILCVLDYDNIDIQRGRILPTDGSAEFNVKYRAVVFKPFKGEVVDGTVVSCSQHGFEVQVGPMKVFVTKHLMPQDLTFNAGSNPPSYQSSEDVITIKSRIRVKIEGCISQVSSIHAIGSIKEDYLGAI
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs.  Pol II is the central component of the basal RNA polymerase II transcription machinery.  It is composed of mobile elements that move relative to each other.  RPB7 is part of a subcomplex with RPB4 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element.  The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft.  The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA.  The RPB4-RPB7 subcomplex recruits FCP1 to Pol II.
What are the official names of this protein?
DNA-directed RNA polymerase II subunit RPB7, RNA polymerase II subunit B7, B16.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
Protein: Y1451_BACVZ
Sequence: MTQMRFTKEDFDTFTIEGLDPRMEVLKEQVRPKLTLLGEHFAPTLSALTGDEMFPHVAKHARRSVNPPADSWVAFANSKRGYKKLPHFQIGLWDTHMFVWFAIIYESPIKEEYGRLLEAKQEDITKQIPGHFVWSPDHTKPGAYKQSDMDQEQLKTLFERLQTVKKAELLCGIQLQKEDVINMNNNEFLQTIEDAFRKLSFLYTLTQKVS
What are the official names of this protein?
UPF0637 protein RBAM_014510.
What is the protein family that this protein belongs to?
Belongs to the UPF0637 family.
Protein: METAA_BACTN
Sequence: MPLNLPDKLPAIELLKEENIFVIDTSRATQQDIRPLRIVILNLMPLKITTETDLVRLLSNTPLQVEISFMKIKSHTSKNTPIEHMQTFYTDFEQMRNEKYDGMIITGAPVEQMDFEEVTYWEEITEIFDWARTHVTSTLYICWAAQAGLYHHYGVPKYPLDQKMFGIFEHRVLEPFHSIFRGFDDCFYVPHSRHTEVRREDILKVPELTLLSESKDAGVYMAMARGGREFFVTGHSEYSPYTLDTEYRRDLGKGLPIEIPRNYYVDDDPDKGPLVRWRAHANLLFSNWLNYFVYQETPYNINDIE
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_NOSS1
Sequence: MAIKERVGLVVSDKMQKTVVVAIENRAPHPKYGKIVVKTRRYKAHDEDNKCKVGDRVRIQETRPLSKTKRWQVAEILNTKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.