PharMolix/UniProtQA huggingface dataset:
Protein: CCD93_XENTR
Sequence: MAARGETPEVETREDEEQGVKLAEILELLVAAGYFRARIKGLSPFDKVVGGMTWCITTCNFDIDVDLLFQENSTIGQKIALTEKIVSVLPKMKCPHRLEPHQIQGLDFIHIFPVIQWLVKRAIETRQEMGDYIRSYSVSQFHKEHSLPEDQDFELRREKTVRTLSETLDVYRPRRKYKRQGGSSELMDEESRVHSTLLEYGRRYGLSKQMKPEKPEDRRVPVPQGLVGKGEVREEEEELRAEEELRIKALMTEMAATGMEEGRLTASTVGQIVGLQSKEIKQMVSEYAEKQSELSAEDRAEYLGAAQQHRRKVASLSKLIGQRKKLLDQLQEKASELQSGCGETRKQLTEVTSHMEKLDQELSVLENMESKADPSVLQKLRDLVAQNESLKAQEQQFRSKCREEMSRLQQNIDGLKAAATEHGEEKEQTQAFEQQYKAEREKLQKIRLLLARRNREIAILQRKIDEVPSRAELTQYQKRFIELYGQVSATHKETKQFFTLYNTLDDKKVYLEKEVNLLNSIHDNFQQAMASPSARDQFLRQMEQIVDGIRQSRNKMEKKKQENKMKRDQLNDEYLELLEKQRLYFKTVKEFKEECRKNETLLSKMKGPTP
What is the function of this protein?
May be involved in copper-dependent atp7a trafficking between the trans-Golgi network and vesicles in the cell periphery.
What are the official names of this protein?
Coiled-coil domain-containing protein 93.
What is the protein family that this protein belongs to?
Belongs to the CCDC93 family.
What are the subcellular locations of this protein?
Early endosome.
Protein: ZN792_HUMAN
Sequence: MAAAALRDPAQGCVTFEDVTIYFSQEEWVLLDEAQRLLYCDVMLENFALIASLGLISFRSHIVSQLEMGKEPWVPDSVDMTSAMARGAYGRPGSDFCHGTEGKDLPSEHNVSVEGVAQDRSPEATLCPQKTCPCDICGLRLKDILHLAEHQTTHPRQKPFVCEAYVKGSEFSANLPRKQVQQNVHNPIRTEEGQASPVKTCRDHTSDQLSTCREGGKDFVATAGFLQCEVTPSDGEPHEATEGVVDFHIALRHNKCCESGDAFNNKSTLVQHQRIHSRERPYECSKCGIFFTYAADLTQHQKVHNRGKPYECCECGKFFSQHSSLVKHRRVHTGESPHVCGDCGKFFSRSSNLIQHKRVHTGEKPYECSDCGKFFSQRSNLIHHKRVHTGRSAHECSECGKSFNCNSSLIKHWRVHTGERPYKCNECGKFFSHIASLIQHQIVHTGERPHGCGECGKAFSRSSDLMKHQRVHTGERPYECNECGKLFSQSSSLNSHRRLHTGERPYQCSECGKFFNQSSSLNNHRRLHTGERPYECSECGKTFRQRSNLRQHLKVHKPDRPYECSECGKAFNQRPTLIRHQKIHIRERSMENVLLPCSQHTPEISSENRPYQGAVNYKLKLVHPSTHPGEVP
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 792.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PDE7B_MOUSE
Sequence: MSCLMVERCGEVLFESPEQSVKCVCMLGDVRLRGQTGVPAERRGSYPFIDFRLLNNTTHSGEIGTKKKVKRLLSFQRYFHASRLLRGIIPQAPLHLLDEDYLGQARHMLSKVGTWDFDIFLFDRLTNGNSLVTLLCHLFNSHGLIHHFKLDMVTLHRFLVMVQEDYHGHNPYHNAVHAADVTQAMHCYLKEPKLASFLTPLDIMLGLLAAAAHDVDHPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRESRLLAHLPKEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHNKDLRLENVQDRHFMLQIALKCADICNPCRIWEMSKQWSERVCEEFYRQGDLEQKFELEISPLCNQQKDSIPSIQIGFMTYIVEPLFREWARFTGNSTLSENMLSHLAHNKAQWKSLLSNQHRRRGSGQDLAGPAPETLEQTEGATP
What is the function of this protein?
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes (PubMed:10872825).  May be involved in the control of cAMP-mediated neural activity and cAMP metabolism in the brain (By similarity).
What are the official names of this protein?
cAMP-specific 3',5'-cyclic phosphodiesterase 7B.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase family. PDE7 subfamily.
Protein: OAT_SCHPO
Sequence: MSAESLLHNTFSTEQIEVLENEYAAHNYHPLPVCFSKAKGAKVWDPEGREYLDFLSAYSAVNQGHCHPKIIEALVEQAQRVTLSSRAFYNDKFGPFAKYITEYFGYEMVIPMNTGAEAVETACKLARLWGYKAKKIPTDEAIILSCVDNFHGRTMGIISMSTDPDARDNYGPYLPNVGPKISGADRVLRYNNIEDLKYYLDTFGPKVAAFLVEPIQGEAGVMVPDDGYLEEAYKLCKAHNVLFIADEVQTGVARTGKMLCIEHSNVKPDVVILGKAISGGVYPVSAVLSSREIMLNFEPGTHGSTYGGNPLGAAVSIAALEVVKEEKLTERAAVLGEKFRTALIECKSPIVQKVRGRGLLNAVVIDESKTNGRTAWDLCLIMRSRGVLAKPTHGNIIRFSPPLVITEEDLMKGIEVIKKSLNDLPTIDMTPYAEKPIH
What are the official names of this protein?
Ornithine aminotransferase car2, Ornithine--oxo-acid aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DCDB_MYCMM
Sequence: MLLSDRDLRAEISAGRLGIDPFDDSLVQPSSVDVRLDCMFRVFNNTRYTHIDPAQRQDELTSVVEPTKGDPFVLHPGEFVLGSTLEIFSLPGDLAGRLEGKSSLGRLGLLTHSTAGFIDPGFSGHITLELSNVANLPITLWPGMKIGQLCILKLTSPSEHPYGSSGVGSKYQGQRGPTPSRSYQNFIRST
What is the function of this protein?
Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
What are the official names of this protein?
dCTP deaminase, dUMP-forming, Bifunctional dCTP deaminase:dUTPase, DCD-DUT.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: RS4_PETMO
Sequence: MARYIGPLEKLSRREGINLYLKGKRSYTEKSALRKRNYVPGQHGRQKQKLTQYAMQLRSKQALKRMYGLMERQFRNTFEEAERSRSGETGEVLMQLLERRLDSVVYQMGFAPNRRTARQIVTHGHILVNGKKVNIPSYRVKVGDVIEVKEKSRNIQQVREGLELVQEGYRNIPNWLNVEIENFRGTFQRLPKIDEMDVPVPLTNIIELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: PROA_ECO45
Sequence: MLEQMGIAAKQASYKLAQLSSREKNRVLEKIADELEAQSESILNANAQDVADARANGLSEAMLDRLALTPARLKGIADDVRQVCNLADPVGQVIDGGVLDSGLRLERRRVPLGVIGVIYEARPNVTVDVASLCLKTGNAVILRGGKETCRTNAATVAVIQDALKSCGLPAGAVQAIDNPDRALVSEMLRMDKYIDMLIPRGGAGLHKLCREQSTIPVITGGIGVCHIYVDESAEIAEALKVIVNAKTQRPSTCNTVETLLVNKNIADSFLPALSKQMAESGVTLHADAAALAQLQAGPAKVVAVKAEEYDDEFLSLDLNVKIVSDLDDAIAHIREHGTQHSDAILTRDMRNAQRFVNEVDSSAVYVNASTRFTDGGQFGLGAEVAVSTQKLHARGPMGLEALTTYKWIGIGDYTIRA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH1_BACCZ
Sequence: MAKVNLEQIEHAVRLILEAIGDDPNREGVLDTPKRVAKMYAEVFSGMHEDPKEHLHKVFGEDHEELVLVKDIPFYSMCEHHLVPFYGVAHVAYIPQGGKVTGLSKLARTVDTIARRPQLQERITSTVANSIMEVLEPHGVMVVVEAEHMCMTMRGVKKPGAKTVTTAVRGVLENDAAARSEILSFIKTK
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: CRKL_RAT
Sequence: MSSARFDSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPNPPMGSVSAPNLSTAEENLEYVRTLYDFPGNDAEDLPFKKGELLVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPTVASTPGAAINPLPSTQNGPVFAKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQNPDDNE
What is the function of this protein?
May mediate the transduction of intracellular signals.
What are the official names of this protein?
Crk-like protein.
What is the protein family that this protein belongs to?
Belongs to the CRK family.
Protein: TPIS_SHEPC
Sequence: MALRRPMVAGNWKMNGSAALAQELFKKFASKLQNDSAEVVLCPPSIYLESVRQLLEANKEALDGSLVRMGAQNLSQHDFGAYTGEVSGQMLKDSGCRYVIIGHSERRRMYGETSNIVAEKFAAAQKHGLTPILCVGESGPAREARRTFEVIAEELDIVIQKNGTMAFDNAIIAYEPLWAVGTGKSATPEQAQEVHAFIRKRLSEVSPFIGENIRILYGGSVTPSNAADLFAQPDVDGGLIGGASLNSSEFLSLCTIAMSA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHYB_ARATH
Sequence: MVSGVGGSGGGRGGGRGGEEEPSSSHTPNNRRGGEQAQSSGTKSLRPRSNTESMSKAIQQYTVDARLHAVFEQSGESGKSFDYSQSLKTTTYGSSVPEQQITAYLSRIQRGGYIQPFGCMIAVDESSFRIIGYSENAREMLGIMPQSVPTLEKPEILAMGTDVRSLFTSSSSILLERAFVAREITLLNPVWIHSKNTGKPFYAILHRIDVGVVIDLEPARTEDPALSIAGAVQSQKLAVRAISQLQALPGGDIKLLCDTVVESVRDLTGYDRVMVYKFHEDEHGEVVAESKRDDLEPYIGLHYPATDIPQASRFLFKQNRVRMIVDCNATPVLVVQDDRLTQSMCLVGSTLRAPHGCHSQYMANMGSIASLAMAVIINGNEDDGSNVASGRSSMRLWGLVVCHHTSSRCIPFPLRYACEFLMQAFGLQLNMELQLALQMSEKRVLRTQTLLCDMLLRDSPAGIVTQSPSIMDLVKCDGAAFLYHGKYYPLGVAPSEVQIKDVVEWLLANHADSTGLSTDSLGDAGYPGAAALGDAVCGMAVAYITKRDFLFWFRSHTAKEIKWGGAKHHPEDKDDGQRMHPRSSFQAFLEVVKSRSQPWETAEMDAIHSLQLILRDSFKESEAAMNSKVVDGVVQPCRDMAGEQGIDELGAVAREMVRLIETATVPIFAVDAGGCINGWNAKIAELTGLSVEEAMGKSLVSDLIYKENEATVNKLLSRALRGDEEKNVEVKLKTFSPELQGKAVFVVVNACSSKDYLNNIVGVCFVGQDVTSQKIVMDKFINIQGDYKAIVHSPNPLIPPIFAADENTCCLEWNMAMEKLTGWSRSEVIGKMIVGEVFGSCCMLKGPDALTKFMIVLHNAIGGQDTDKFPFPFFDRNGKFVQALLTANKRVSLEGKVIGAFCFLQIPSPELQQALAVQRRQDTECFTKAKELAYICQVIKNPLSGMRFANSLLEATDLNEDQKQLLETSVSCEKQISRIVGDMDLESIEDGSFVLKREEFFLGSVINAIVSQAMFLLRDRGLQLIRDIPEEIKSIEVFGDQIRIQQLLAEFLLSIIRYAPSQEWVEIHLSQLSKQMADGFAAIRTEFRMACPGEGLPPELVRDMFHSSRWTSPEGLGLSVCRKILKLMNGEVQYIRESERSYFLIILELPVPRKRPLSTASGSGDMMLMMPY
What is the function of this protein?
Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light: the Pr form that absorbs maximally in the red region of the spectrum and the Pfr form that absorbs maximally in the far-red region.  Photoconversion of Pr to Pfr induces an array of morphogenetic responses, whereas reconversion of Pfr to Pr cancels the induction of those responses.  Pfr controls the expression of a number of nuclear genes including those encoding the small subunit of ribulose-bisphosphate carboxylase, chlorophyll A/B binding protein, protochlorophyllide reductase, rRNA, etc.  It also controls the expression of its own gene(s) in a negative feedback fashion.  Involved in the flowering time regulation.  Involved in light-regulated circadian phase control that triggers stomatal aperture, stomatal conductance, and CO(2) assimilation.  Implicated in red light perception, and, to a lower extent, in blue light signaling (PubMed:12177480).  Regulates temperature responses by associating with the promoters of key target genes in a temperature-dependent manner and subsequently repressing their expression probably in a PIF4-dependent manner.  Thermal timer that integrates temperature information over the course of the night (PubMed:27789797).
What are the official names of this protein?
Phytochrome B, Protein LONG HYPOCOTYL 3, Protein OUT OF PHASE 1.
What is the protein family that this protein belongs to?
Belongs to the phytochrome family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleoplasm. Nucleus speckle. Nucleus. Note=Cytoplasmic in darkness, but translocated to the nucleus upon illumination, when associated with PAPP5 into speckles.
Protein: ACYP_SYNAS
Sequence: MMKRVHVYVKGKVQGVFFRAHTRKAALRFHVNGWVRNLPNGRVEAVFEGRSPEVNALIDWCRQGPSHAIVEHLDVCEETYTGEFDDFRILYDERAS
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: NUOA_SODGM
Sequence: MSITTEITAHYWAFAVFLLSALGLCVFMLTGGFLLGARARARSKNVPFESGIDPVGTARLRLSAKFYLVAMFFVIFDVETLYLYAWATAIREAGWVGFIEATIFILILLAGLVYLVRIGALDWTPERSRRLRRAGPIGETPRHQE
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS3_GLOC7
Sequence: MGQKIHPVGFRLGITKEHKSRWFADKYHYPELLQEDRKIRQYVEKNLSNAGISDIRIERKADQVDIEIHTARPGVVVGRGGSGIEALRVGLQNALGGHRQIRINVVEVARVDADATLIAEYIAQQLERRVSFRRVVRQAIQRAQRAEVKGIKVQVSGRLNGAEIARTEWIREGRVPLHTLRADIDFAYRTAKTIYGILGVKIWVFKGEIIPGQEEQAPAQPATTPKRQRRRQQFEDRSNE
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: SYGA_CAMC5
Sequence: MTFSEIILTLQSYWREQGCVILQPYDMPAGAGTYHQATFLRSLGPKPWATAYVAPSRRPTDGRYGENPNRLGAYYQFQVLIKPSPENIQELYLKSLERLGLDLKKHDIRFVEDNWESPTLGAWGLGWEVWLDGMEVTQFTYFQQVGGIACELISGEITYGLERLAMYLQDIDNVYDIVWDDKNGVVTYGDVHKQGEYEWSKYNFEIADTAMLFNQFENAFKECKRCLEAKISLPAYDYCMLAAHTFNVLDARGAISVTQRQEHILKIRELTKECALTYKASLEEKGE
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_PARUW
Sequence: MFKNLCDKIMTQKILITSALPYANGPLHFGHIAGAYLPADCYARFQRLMKKDVLYICGSDEYGIAITLSADLAGRTPQEHVDLFHHINQSFFEQLQISFDHYSRTTWKGHVEPTHQFFNDLLQNGYIEERTTDQLYSEKDQKFLADRYVVGTCPRCGFENARGDECPCCGASYEATELKNPRSKLTDASLILRPTKHWFLLLEKFKKPLMEWLETKNWKPNVINFIRGYIDHLHARAITRDMKWGISVPLPDSEGKVLYVWFDAPIGYISATKEWALLRGEEKLWEKYWLDPETKLVNFIGKDNIPFHASIFPAMIMGQNQPYKLVDELPANEFYNLEGKQFSKSDGWYIDLEDFFKHYTSDQIRYAIASNAPETSDSEFTWKDFQLRCNSDLLGKYGNLVNRVLVFIHNQCQGKVPESGVLEEQDRKFLKNIQDLVDQAAASYSTFKVRKASQIMMELSQLGNVYFDSKKPWQDAKNDYTKGRMHTTLNCCMECLKALALISFPIIPTAASKVWQFLGFQTPLEQEDWNRVKIEKLPLNQKILTPQILFQRVENEAVEREILKLQQLSLTKEKKSTPQSTQISISENILLKPLVDIEDFRKLDLRVGKIIQANPVPKSKKLFQLLVDIGIEKRIVVAGVAEFYKVEDLIGKNVVVVANLKPANLMGVTSQGMLLAAKGEGNLKLISIEDVAPGSLVS
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPB5_ASFK5
Sequence: MAMQKLFTYIYEFIEYRKMVLLEEKVPYDKFVQMIFNTGFFRINAETLNHGIVSVFIFGANGKYVHHGGDMRTLLTNALNEKKQYEELILIVDKPILGKKNILDIIVEQRAANPTVVINIYPYHLFCINIPKVSAIPRHKLITQEEAQAFLGREYLQPQDLMQISASDPPVVWLGGRPGDFVQIERPSETAMHAVVIRYITKSKI
What is the function of this protein?
Component of the DNA-directed RNA polymerase (RNAP) that catalyzes the transcription in the cytoplasm of viral DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase RPB5 homolog, RPB5 homolog.
What is the protein family that this protein belongs to?
Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Host cytoplasm. Virion. Note=Found in association with viral nucleoid.
Protein: RL23_ACIBY
Sequence: MNNERIYQVLKGPVFSEKAQVLGDTAGVQVFKVDINATKLEIKKAVEKLFGVEVVKVNTTITKGKTKRFGRTLGRRSDVKKAYVTLKAGQDVEMADLGDTAESAAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: CB050_BOVIN
Sequence: MGSRPTPGLQRTTSAEYRLPSTRPPASVPSTAPGGPVVGRGPTGGPQAPKAKWSALGADGVQRDQLWRELLEAERRSQQRWAQNWSFLKDYDPMGNKKEPVKLPDHVPRFSDTVPNSTNRAVGSRVDTPLGKTLIGLDFFFVEGARKKKLEEELQPI
What are the official names of this protein?
Uncharacterized protein C2orf50 homolog.
Protein: GCSPA_ACIC5
Sequence: MRYLPKSPADREAMLREIGAASIDELFAIIPEEFRLTRDLAIPRQMGESEIVDHFQAAAARNANGYASFLGAGAYRHYRPVLIDTIVQRGEFLTSYTPYQAEITQGTLQAIFEFQTMICELTGMDIANASMYDGSTGAAEAVMMAIRVTGRDKVLVSRSVHPEYREVMHTYAQHQGHDAAEVEYIREGAQAGRVDLAALEAAVTEETACVLVQSPNFFGVIEDIPAIAEIAHKKGALLIVSIAEALSLGAVRPPVEADIVSLEAQSFGVALSYGGPYCGVLAAKEKYLRQMPGRLVGETKDSQGRRGFVLTLSTREQHIRREKATSNICTNQALVALMATVYMTIYGKQGIKDLALQNLAKADYAAKTLGQSGKLLFAGSPRFHEFVLETSETPAQVNERLLEEKIIGGLPLGKWYPELGHAALWCATEVTTREQIDRAAQVLAHAPALAAR
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: GP7_BPP22
Sequence: MLYAFTLGRKLRGEEPSYPEKGGKGGADKSAKYAAEAQKYAADLQNQQFNTIMNNLKPFTPLADKYIGSLEGLSSLEGQGQALNNYYNSQQYQDLAGQARYQNLAAAEATGGLGSTATSNQLSAIAPTLGQQWLSGQMNNYQNLANIGLGALQGQANAGQTYANNMSQISQQSAALAAANANRPSAMQSAIGGGASGAIAGAGLAKLIGSSTPWGAAIGGGIGLLGSLF
What is the function of this protein?
Inner capsid protein that plays a role in viral DNA ejection into the host cell (PubMed:26245366, PubMed:29590587).  Assembles into an extracellular trans-envelope channel completed by the internal virion proteins gp7 and probably gp16 (PubMed:30886360).  This channel allows the delivery of the viral genome into the cell cytoplasm (PubMed:30886360).
What are the official names of this protein?
Internal virion protein gp7, Ejection protein gp7, E protein gp7.
What is the protein family that this protein belongs to?
Belongs to the podoviruses gp7 family.
What are the subcellular locations of this protein?
Virion.
Protein: ENA2_HORSE
Sequence: EVERKHPLGGSRPGRCPTVPPGTFGHCACLCTGDASEPKGQKCCSN
What is the function of this protein?
Has antibiotic activity against several equine uterine pathogens; S. zooepidemicus, E. coli and P. aeruginosa.  Highly efficient against S. zoopedemicus.  Not active against K. pneumoniae.  Selectively inactivates microbial serine proteases (subtilisin A and proteinase K) without inhibiting mammalian serine proteases (human neutrophil elastase, human cathepsin G and bovine pancreatic trypsin).
What are the official names of this protein?
Antimicrobial peptide eNAP-2.
Protein: PI3R5_PIG
Sequence: MQPGATTCTEDRIQHALERCLHGLSLSRRSTSWSAGLCLNCWSLQELVSRDPGHFLILLEQILQKTREVQEKGTYDLLAPLALLFYSTVLCTPHFPPDSDLLLKAARTYHRFLTWPVPYCSICQELLTFIDAELKAPGISYQRLVRAEQGLSTRSHRSSTVTVLLLNPVEVQAEFLDVADKLSTPGPSPHSAYITLLLHAFQATFGAHCDLSGLHRRLQSKTLAELEAIFTETAEAQELASGIGDAAEARQWLRTKLQAVGEKAGFPGVLDTAKPGKLRTIPIPVARCYTYSWNQDSFDILQEILLKEQELLQPEILDDEEDEDEEDEEEDLDADGHCAERDSVLSTGSAASHASTLSLASSQASGPTLSRQLLTSFVSGLSDGVDSGYMEDIEESAYERPRRPGGHERRGHRRPGQKFNRIYKLFKSTSQMVLRRDSRSLEGSPDSGPPLRRAGSLCSPLDSPTLPPSRAQGSRSLPQPKLSPQLPGWLLAPASRHQRRRPFLSGDEDPKASTLRVVVFGSDRISGKVVRAYSNLRRLENNRPLLTRFFKLQFFYVPVKRSRGTGTPTSPAPRSQTPPLPTDAPRHPGPAELGAAPWEESTNDISHYLGMLDPWYERNVLGLMHLPPEVLCQSLKAEPRPLEGSPAQLPILADMLLYYCRFAARPVLLQVYQTELTFITGEKTTEIFIHSLELGHSAATRAIKASGPGSKRLGIDGDREAVPLTLQIIYSKGAISGRSRWSNMEKLCTSVNLSKACRQQEELDSSTEALTLNLTEVVKRQTPKSKKGFNQISTSQIKVDKVQIIGSNSCPFAVCLDQDERKILQSVIRCEVSPCYKPEKSSLCPPPQRPSYPPAPATPDLCSLLCLPIMTFSGALP
What is the function of this protein?
Regulatory subunit of the PI3K gamma complex.  Required for recruitment of the catalytic subunit to the plasma membrane via interaction with beta-gamma G protein dimers.  Required for G protein-mediated activation of PIK3CG.
What are the official names of this protein?
Phosphoinositide 3-kinase regulatory subunit 5, PI3-kinase regulatory subunit 5, IB PI3-kinase p101 subunit, PI3-kinase p101 subunit, Phosphatidylinositol 4,5-bisphosphate 3-kinase regulatory subunit, PtdIns-3-kinase regulatory subunit, PtdIns-3-kinase p101, p101-PI3K.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell membrane; Peripheral membrane protein. Note=Predominantly localized in the nucleus in absence of PIK3CG/p120 (PubMed:12507995, PubMed:15611065). Colocalizes with PIK3CG/p120 in the cytoplasm (PubMed:12507995, PubMed:15611065). Translocated to the plasma membrane in a beta-gamma G protein-dependent manner (PubMed:12507995, PubMed:15611065).
Protein: RL14_META3
Sequence: MKGFGSKVIRSLPNGARLICADNTGAKELEIIAVKGYKGVARRLPAGGVGSLVFVSVKKGTPEMRKQVLPAIIIRQKKEYRRPDGSRVKFEDNAAVIVTPEGSPKGSEIKGPVAKEAAERWAGVSRLAKIIH
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: NHAA_HAEIG
Sequence: MNFLLCIFKGVYVIKLIQRFFKLESAGGILLLFSAVVAMLLANSPLSNQYNDFLNLPVSLQIGSFSINKTLIHWINDGFMAVFFVLVGMEVKKELFEGALSTYQQAIFPAIAAIGGMVIPAVVYWFIAKQDPSLANGWAIPMATDIAFALGIMALLSKQVPLPLKIFLLALAIIDDLGAIVVIALFFSHGLSVQALIFSAVAIIALILLNRFKVSALCAYMVVGAILWASVLKSGVHATLAGVIIGFSIPLKGKKGERPLDDFEHILSSWSSFVILPLFAFANAGVSFAGIDVNMISSPLLLAIASGLIIGKPVGIFGFSYISVKLGLAKLPDGINFKQIFAVAVLCGIGFTMSMFLASLAFDANAGESVNTLSRLGILLGSTVSAILGYLFLKQTTKLS
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PIRL6_ORYSJ
Sequence: MERVLKSARESGSLNLSNRSLREVPKEVYNNLDTGAQDEKWWEGVDLQKLILAHNNLEVLREDLRNLSSLVVLNISHNNISSLPAAIGDLPLLKSLDVSSNQINAFPEEIGFATALVKVDCSNNCLTDLPVSLARCLELSELNASNNTISVLPDELAGCSKLFRLNLEGNKLVTLSDKMFMSWTMLTEMNAAKNLLTAIPDGIGALSKLIRLDLHQNKITLIPPSIKDCSSLAEFYMGNNLLTSIPEDIGMLSNLGILDLHSNQLKEYPVGACRLKLSFLDLSNNSLSGLPAELGTMTTLRKLLLTGNPMRTLRSSLVSGPTTALLKYLRSRLSSDEGASGSGSTPTKDDQIAAARRLSLSSKELDLSGLGVTSVPPAAWETNDVMKLDLSKNSIEDLPNELSLCSSLQSLILSNNKIKRWPGTVFSSLASLSLLKLDNNPLAEILATDLEALSKLEVLDLSGSASSLPEPSAVSKLPHLKELYLRRMKLHGFPDSLLGLKLLRILDLSQNYLTSVPEGIKDLTSLIELDLSDNNITTLPPELGLLEPNLQVLKLDGNPLRSIRRTLLERGTKAILKYLKEKLPAE
What is the function of this protein?
Leucine-rich repeat protein that likely mediates protein interactions, possibly in the context of signal transduction.
What are the official names of this protein?
Plant intracellular Ras-group-related LRR protein 6, Intracellular Ras-group-related LRR protein 6, OsIRL6.
What is the protein family that this protein belongs to?
Belongs to the SHOC2 family.
Protein: RMF_ALTNA
Sequence: MKRQKRDKLTRAHSKGYQAGISGRSKDICPFQQNDARSEWLGGWREAVEDRHVGLSVK
What is the function of this protein?
During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes).
What are the official names of this protein?
Ribosome modulation factor, RMF.
What is the protein family that this protein belongs to?
Belongs to the ribosome modulation factor family.
What are the subcellular locations of this protein?
Cytoplasm.