PharMolix/UniProtQA huggingface dataset:
Protein: T2R20_PONPY
Sequence: MMSFLHIVFSILVLVAFILGNFANGFIALTNFIAWVKRQKISSADQIIAALAVSRVGLLWVILLHWYSTVLNPTSSSLKVTIFVSNAWAVTNHFSIWLATSLSIFYLRKIVNFSRLIFHHLKRKAKSVVLVIVLGALFFLVCHLVMENTYINVWTKEYEGNVTWKIKLRNAMYLSNLTVATLANLIPFTLTLISVLLLIYSLCKHLKKMQLHGKGSQDPSTKIHIKALQTVTSFLILLAIYFLCLIISFWXSETQLKELVLMLCQAVGIIYPSFHSFILIWGNKTLRQTFLSVLWQVTCWSKGQNQSTP
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 20, Taste receptor type 2 member 49, T2R49.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: VA4_SOLGE
Sequence: MKTFVLVSCLLVFTQIIYAVDIKELKIMNRILEKCIRTVPKGENDPINPLKNVNVLYCAFSKRGIFTPKGVNTKQYINYCEKTIINPADIKQCKKLISKCIKKVYDRPGPIIERSKNLLSCVLKKGVLELTVYGKKK
What are the official names of this protein?
Venom allergen 4, Venom allergen IV.
What is the protein family that this protein belongs to?
Belongs to the ant venom allergen 2/4 family.
What are the subcellular locations of this protein?
Secreted.
Protein: TXLB1_CYRSC
Sequence: MKTSMFLTLTGLVLLFVVCYASESEEKEFPKELLSSIFAADSDFKEEERGCFGYKCDYYKGCCSGYVCSPTWKWCVRPGPGRR
What is the function of this protein?
Weakly inhibits 5HT3A receptors and Kv1. 3/KCNA3 voltage-gated potassium channels (PubMed:29483648).  Agglutinates erythrocytes (By similarity).
What are the official names of this protein?
U5-theraphotoxin-Hs1b 1, U5-TRTX-Hs1b, Lectin SHL-Ib1.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 51 (Hntx-8) subfamily. Hntx-8 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PILB2_MOUSE
Sequence: MALLISLPGETPAMAQILLLLSSACLHAGNSARSNGGNDFGVNQPERCSGVQGGSIDIPFSFYFPWKLAKDPQMSIAWRWKDFFGHFIYNSSMPFIHEHFKGRLILNWTQGQTSGVLRILNFKESDQTWYFCRVFLQTTEGIKFWQSLPGTQLTLTQALNTTMRSPFIVTSEFTTAGLEHTRDKRNPSLMNLGAMVTMLLAKVVVIILVYGWMIFLRWKQRPDPA
What is the function of this protein?
Paired receptors consist of highly related activating and inhibitory receptors and are widely involved in the regulation of the immune system.  PILRB2 is probably a cellular signaling activating receptor that associates with ITAM-bearing adapter molecules on the cell surface.
What are the official names of this protein?
Paired immunoglobulin-like type 2 receptor beta-2, Activating receptor PILR-beta-2.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RL11_ACIBY
Sequence: MAKKIDGYIKLQVPAGKANPSPPIGPALGQRGVNIMAFCKEFNAATQKVEPGLPIPVVITVYNDKSFTFIMKTPPASILLKKAAGIQKGSSVPNKTKVGKLTRAQLEEIATTKEPDLTGADLDARVRTIAGSARSMGLEVEL
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: ACO12_HUMAN
Sequence: MERPAPGEVVMSQAIQPAHATARGELSAGQLLKWIDTTACLAAEKHAGVSCVTASVDDIQFEETARVGQVITIKAKVTRAFSTSMEISIKVMVQDMLTGIEKLVSVAFSTFVAKPVGKEKIHLKPVTLLTEQDHVEHNLAAERRKVRLQHEDTFNNLMKESSKFDDLIFDEEEGAVSTRGTSVQSIELVLPPHANHHGNTFGGQIMAWMETVATISASRLCWAHPFLKSVDMFKFRGPSTVGDRLVFTAIVNNTFQTCVEVGVRVEAFDCQEWAEGRGRHINSAFLIYNAADDKENLITFPRIQPISKDDFRRYRGAIARKRIRLGRKYVISHKEEVPLCIHWDISKQASLSDSNVEALKKLAAKRGWEVTSTVEKIKIYTLEEHDVLSVWVEKHVGSPAHLAYRLLSDFTKRPLWDPHFVSCEVIDWVSEDDQLYHITCPILNDDKPKDLVVLVSRRKPLKDGNTYTVAVKSVILPSVPPSPQYIRSEIICAGFLIHAIDSNSCIVSYFNHMSASILPYFAGNLGGWSKSIEETAASCIQFLENPPDDGFVSTF
What is the function of this protein?
Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels (PubMed:16951743).  Preferentially hydrolyzes acetyl-CoA (PubMed:16951743).
What are the official names of this protein?
Acetyl-coenzyme A thioesterase, Acyl-CoA thioester hydrolase 12, Acyl-coenzyme A thioesterase 12, Acyl-CoA thioesterase 12, Cytoplasmic acetyl-CoA hydrolase 1, CACH-1, hCACH-1, START domain-containing protein 15, StARD15.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RPO5_PYRHO
Sequence: MSGKNEFNIFKHVLVPEHRILSEEEKKALLEKYKITPAQLPQIRASDPAVKALGAKPGDIIEIKRRSPTAGVYYYYRVVVED
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo5, DNA-directed RNA polymerase subunit H.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDL_STRR6
Sequence: MKQTIILLYGGRSAEREVSVLSAESVMRAVDYDRFTVKTFFISQSGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSVQGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEVEEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVGLLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKVTMDIPAKISDDVVAVMRQNAETAFRAIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWENMGISYPELIERLVDLAKESFDKREAHLI
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMJ_NEIGO
Sequence: MTDILIDDTATEAVRTLIRAFPLVPVSQPPEQGSYLLAEHDTVSLRLVGEKSNVIVDFTSGAAQYRRTKGGGELIAKAVNHTAHPTVWDATAGLGRDSFVLASLGLTVTAFEQHPAVACLLSDGIRRALLNPETQDTAARINLHFGNAAEQMPALVKTQGKPDIVYLDPMYPERRKSAAVKKEMAYFHRLVGEAQDEVVLLHTARQTAKKRVVVKRPRLGEHLAGQAPAYQYTGKSTRFDVYLPYGADKG
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YGGU_SALPK
Sequence: MSAVTRCEDGLVLRLYIQPKASRDSIVGLHGDEVKVAITAPPVDGQANSHLIKFLGKQFRVAKSQIVIEKGELGRHKQVKIIHPQQIPPEIAALTE
What are the official names of this protein?
UPF0235 protein YggU.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: TI214_SOLTU
Sequence: MIFQSFLLGNLVSLCMKIINSVVVVGLYYGFLTTFSIGPSYLFLLRALVMEEGTEKKVSATTGFITGQLMMFISIYYAPLHLALGRPHTITVLALPYLLFHFFWNNHKHFFDYGSTTRNSMRNLSIQCVFLNNLIFQLFNHFILPSSMLARLVNIYLFRCNNKILFVTSGFVGWLIGHILFMKWLGLVLVWIRQNHSIRSNKYIRSNKYLVLELRNSMARIFSILLFITCVYYLGRIPSPILTKKLKEASKTEERVESEEERDVEIETASEMKGTKQEQEGSTEEDPYPSPSLFSEEGWDPDKIDETEEIRVNGKDKIKDKFHSHLTETGYNNINTSNSPIYDYQDSYLNNNNTGNLENLKLQLLDKKNENQDLFWFQKPLVSLLFDYNRWNRPFRYIKNNRFEQAVRTEMSQYFFDTCKSDGKQRISFTYPPSLSTFWKMIKRKIPLLSLQKTLPNELDTQWVSTNKEKSNNLNKEFLNRLEILAKESLSMDILETRTRLCNDDTKKEYVPKMYDPLLNGPYRGTIKKGVSSSIINNTLLENWEKRVRLNRIHTIFLPNMDYQEFEQKAYTIDKKPLSTEIDEFLTLINELGNEPKSSLNLKGLSLFSDQEQRRVNSEKRTKFVKFVFNAIDPNETKSGKKSIGIKEISKKVPRWSHKLITELDQQMGEFQDRASIDHQLRSRKAKRVVIFTDNNATNDPEEEVALISYSQQSDFRRGIIKGSMRAQRRKTFISKLFQANVHSPLFVDRITPLRLFSFDISELIKPIFRNWTGKEGEFKILESREEQTKREEKKEKDKKEDNKRKEQARIAIEEAWDNIPFAQIIRGYMLITQSILRKYILLPSLIIAKNLGRMLFLQLPEWSEDLQEWNREMQIKCTYNGVQLSETEFPKDWLRDGIQIKILFPFCLKPWHISKLYPSRGELMKKQKQKDDFCFLTVWGMEAELPFGSPRKRPSFFEPIFKELEKKIGKLKKKYFLTLKIFKGKTKLFRRVSKETKKWFIKSIGFLKKIKKELSKVNPIVLFRFKEISESNETKKEKDYLISNQIINESFSQIESGNWPNSSLIETKMKDLTDRTSTIKNQIERITKDKKKVTPEIDINPNKTNNIKKLESPKKFFQILQRRNTRVIWKFHYFLKLFIQRLYIDLFLSIINIPRITTQLFLESTNKLIEKFISNNEINQEKITNKKKIHFIFISTIKKSLYNISKKNSHIFCDLSYLSQAYVFYKLSQTQVINLSKFRSVLQYNTTSCFLKTKIKDYFKTLGIFHSELKHKKLQSYRINQWKNWLRWHYQYDLSQIRWSRLMPKKWRTKVNQSCMAKNKNRNLNKWNSYEKDQLIHYKKENDSELYSLSNQKDNFKKCYRYGLLAYKSINYENKSDSFFSRLPFQVKKNLEISYNSNTSKHNFVDMPGNLHINNYLRKVNILDIERNLDRKYFDWKIIHFSLRQKGDIEAWVKIDTNSNPNTKIGINNYQIIDKIEKKGVFYLTTHQNPEKTQKNSKKVFFDWMGMNEKIFNRPILNLEFWFFPEFVLLYNVYKIKPWIIPSKFLLFNLNTNENVIQNKNQKQNFFLPSNKKIKNRSQETKEPPSQRERGSDIENKGNLSPVFSKHQTDLEKDYVESDTKKGQNKKQYKSNTEAELDLFLKRYLLFQLRWNDALNKRMLENIKVYCLLLRLINPTKITISSIQRREMSLDIMLIQANLPLTDLMKKGVLIIEPIRLSVKHNGQFIMYQTIGISLVHKSKHQTNQRYREQRYVDKKNFDEFILQPQTQRINTEKTHFDLLVPENILWSRRRRELRIRSFFNSLNWNVVDRNSVFCNETNVKNWSQFLGERKPLYKDKKKLIKFKFFLWPNYRLEDLACMNRYWFDTNNGSRFSILRIHMYPRLKIN
What is the function of this protein?
Involved in protein precursor import into chloroplasts.  May be part of an intermediate translocation complex acting as a protein-conducting channel at the inner envelope.
What are the official names of this protein?
Protein TIC 214, Translocon at the inner envelope membrane of chloroplasts 214, AtTIC214.
What is the protein family that this protein belongs to?
Belongs to the TIC214 family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: SLT11_EMENI
Sequence: MPPQIKQDLNRSGWETTDFPSVCENCLPENPYVQMLKEDYGAECKICTRPFTIFRWKADRTARTKRTNICLTCARLKNCCQCCMLDLSFGLPIVVRDAALKMVAPGPQSSINREYYAQGHEKEIEEGRGAVEEYEKTDEKARELLRRLANSEPYYRKPRQLEAPEEDGETQGPSDATVVRSRYGNGPGPVRTSESRRGTPLPGRGRGGVRGGRPFPGTAQLPPSQADILPPADPNITSLFVTGVEDDLPEHALRSFFVQFGQLRSLVCSHRAHCAFINYAARESAEAAAKHCQGKAVVQGCPLRVRWGKPKALDNMDREERLKYAREGRQAVGSLGNADQGTKAITAGTEKEQIPRQVAVAPPPGSGEVQYSSMSGD
What is the function of this protein?
Involved in pre-mRNA splicing.  Facilitates the cooperative formation of U2/U6 helix II in association with stem II in the spliceosome.  Binds to RNA (By similarity).
What are the official names of this protein?
Pre-mRNA-splicing factor slt11.
What is the protein family that this protein belongs to?
Belongs to the SLT11 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ASTE_ECO27
Sequence: MDNFLALTLTGKKPVITEREINGVRWRWLGDGVLELTPLTPPQGALVISAGIHGNETAPVEMLDALLGAISHGEIPLRWRLLVILGNPPALKQGKRYCHSDMNRMFGGRWQLFAESGETCRARELEQCLEDFYDQGKESVRWHLDLHTAIRGSLHPQFGVLPQRDIPWDEKFLTWLGAAGLEALVFHQEPGGTFTHFSARHFGALACTLELGKALPFGQNDLRQFAVTASAIAALLSGESVGIVRTPPLRYRVVSQITRHSPSFEMHMANDTLNFMPFEKGTLLAQDGEERFTVTHDVEYVLFPNPLVALGLRAGLMLEKIS
What is the function of this protein?
Transforms N(2)-succinylglutamate into succinate and glutamate.
What are the official names of this protein?
Succinylglutamate desuccinylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
Protein: CYTA_RAT
Sequence: MDPGTTGIVGGVSEAKPATPEIQEVADKVKRQLEEKTNEKYEKFKVVEYKSQVVAGQILFMKVDVGNGRFLHMKVLRGLSGDDDLKLLDYQTNKTKNDELTDF
What is the function of this protein?
This is an intracellular thiol proteinase inhibitor.
What are the official names of this protein?
Cystatin-A, Cystatin-alpha, Epidermal stefin, Epidermal thiol proteinase inhibitor.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y027_BACC7
Sequence: MMRGGMGNMNNMMKQMQKMQKEMAKAQEELGEKTVEGTAGGGMITVIANGHKQILEVKVKEEVVDPEDIEMLQDLVLAATNDALKKADELSNSTMGKFTKGLNLPGGMF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein BCAH187_A0027.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RL23_DESOH
Sequence: MVYHDLIRRPVTTEKTTLQKETANQVTFEVDRRANRVEIKRAVEQVFNAKVAAVNTATVKGKKKRMGRNIGKRKDWKKAVVTLMPGERIDFFEGV
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: BPT_CERS1
Sequence: MRHTLPIAPQFYVTAPQSCPYLEGRLERKLFTALQGEHAQKLNDTLSKQGFRRSQNVLYRPSCAECSACLSARIRVADFEPTRTQRRVMKRNADLRRNATSPWATEDQYALFRRYLDDRHADGGMADMDIFEFAAMIEETPIRSRVIEYSRPGDTPSNRPLSAVCLTDIFDDGLSMVYSFYDPDLAGRSLGAYVILDHIEIAREAGLPYVYLGYWVPGSRKMGYKASYSALEIYKGGRWQDIGQPSDHRAELHPLSVDPIAEQVARISLPEARSGDRSRD
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTLD_VIBCH
Sequence: MKKNAVHFGAGNIGRGFIGKLLADADIAVTFADVNEPLVDQLSHQQEYKVKVVGSECKMETVSHVTAVNSASEALIERIIKTDLVTTAVGPTVLDIIAKTIAKGLSARFAAGNTQPLNIIACENMVRGTTHLKQQVYQFLTTEEQQQADALVGFVDSAVDRIVPPLQAANDDPLEVTVESFSEWIVDEQQFKGEIPQIEGMEKTDNLMAFVERKLFTLNTGHCVTAYLGCLKGHRTIREAIEDPCIHAQVKQAMQESGEVLIRRYGFDRALHSAYIEKILSRFANPYLVDEVDRVGRQPLRKLSANDRLIKPLLGTIEYGLPNGMLLKGIAAALKYRNSSDPQAVELQQSIEKEGVRSTLARYTGLAAESVEAQQIEALYQQMD
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: PACC_PARBR
Sequence: MSSRENPDTSAPMAQQQPQQQQQQQQPQPQQQQQQQQQQQQAQQTTQQQQSPQQPSQQSPLPAAAAAASVIAPVPLPQNGSNGAALGVTENLVCQWQGCQERLPTAEALYEHVCERHVGRKSTNNLNLTCGWANCRTTTVKRDHITSHIRVHVPLKPHKCDFCGKAFKRPQDLKKHVKTHADDSVLVRSPEPGPGTRPPNGMFGVGVGADGKCSLGHVHGQGYPHGAPQYYQTPHQQHPSNPSYGNVYYAIGSDSHQASYESKKRGYDALNEFFGDLKRRQFDPTSYAVVGQRLLNLHGLPLPLVNGAAVAVPEYQTQPMPAMVSVGHGGGHSGGGGYQPASPMQSYHLPPMGNLRTKADLMNIDQFLEQMQSTVYESDDHVAAAGVAQPGAHYVQHGGMSYRTSHSSNNANANANASHTATSSPPSAATNIPSTHATATTTTTSAPMIPTSSAARLLPTHAPRHALTPPSSAQSYTSGRSPVSVSSTHHHIPPSHHYTHTHNHNHNHPNSSAGMYPTLPATSAQDGSSTNTYHGVSGAAAPSTLSSVFDSEGGRRYAGGCCRGLDRGLWRRHHRRRQGSPSMSFAEVGGNDTKTASPSMSFSASVIDPALQAGSEKQSGSSGSGGEAGAGAGAGAGAGEERNGSSSSPTADVEEVSRALSSANATTTMATKTAPPEVPSHTVEQWVANVRLLEKLRLYIYERLSR
What is the function of this protein?
Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH.  At alkaline ambient pH, activates transcription of alkaline-expressed genes (including pacC itself) and represses transcription of acid-expressed genes (By similarity).
What are the official names of this protein?
pH-response transcription factor pacC/RIM101.
What is the protein family that this protein belongs to?
Belongs to the pacC/RIM101 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: QUEC_SULSY
Sequence: MLKKENIIVLLSGGMDSAVLLWLSKTIFKDVYTISYSYGQKHSIELEYAKELSKIAGVKEHFIVEVPHLKQLKGSALTDENLEIPSENYPDEPPITTVPMRNLIFLSIAASFADVYEIENIGIGIHSLDSPYPDCRAEFASSAEAVINASSVMVAKKKNRIKIFTPFLGMSKTDIAKLGRELGVPFEKTYSCYKGTVPPCGECATCRQREEALRETFSDTTT
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: DPO4_VIBC3
Sequence: MQDRIRKIIHVDMDCFFAAVEMRDNPAYREIALAVGGHEKQRGVISTCNYQARKFGVRSAMPTAQALKLCPQLHVVPGRMSVYKSVSQQIQTIFQRYTSLIEPLSLDEAYLDVSESTAYQGSATLIAQAIRRDIWQELNLTASAGVAPIKFLAKVASDLNKPNGLYVVTPDKVQEMVDSLPLEKIPGVGKVALEKLHQAGLYVGADVRRADYRKLLHQFGRLGASLWKKSHGIDEREVVTERERKSVGVEYTFSQNISTFQECWQVIEQKLYPELDARLSRAHPQRGIIKQGIKVKFADFQQTTIEHVHPALELDYFHELLEQVLTRQQGREIRLLGLSVMLKPELQMKQLSMFPSDGWQ
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH_RICPR
Sequence: MDSKVVIYTDGACSGNPGPGGWGALLHFNDTSKKIFGYELVTTNNRMEMTAALEALRILKKSSVVEIYTDSKYLQHGITVWIHNWIKNNWCKSNNAPVKNADLWQKLYSELSKHTIMWKWVKGHASNSGNIAADKLAVQGRETAMEILKCLG
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HI, RNase HI.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPESP_RAT
Sequence: MKPVVLVALLWLWPSSFLAYPTATVLPDEEQNLNHYVQILQNLIMSVPTKEQGFGRKFRSSRTVDGAEARSLSSEMLLTPGLVSAQEVTTPETEVMLTSMVEKTTFPSSGFTMESEKRRTHSKAFWSIQPNNVSIVLHTEEPYIEKEPEPEPELETEEESRRLATEPEPEPESESAPETETRQTAESEEEVETSTAQNKVRTGTSRMSTVITQTTNTQGTPNTVTVKTINNLDVSTESEDVPQLSGQSEILNVEDLPGHHSLSTRHENILRKISNINSQIHQGLLSDHSSPAYKEFIKASREHLKRSLALAAAAEHKLQQMYGSNVFLDGHTSDPDDDMEVIINMLYNSRSKLSDYFTINHVPSELREKATVVIAVLKKILCVDQVEMQSLIRKLLSNNMKILNILNVP
What is the function of this protein?
Involved in fertilization ability of sperm.
What are the official names of this protein?
Sperm equatorial segment protein 1.
What is the protein family that this protein belongs to?
Belongs to the SPESP1 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Small proacrosomal granules (during the Golgi phase), enlarged acrosomal vesicles (during the cap phase), acrosome (during the elongating phase), equatorial segment of the acrosome (during the maturation phase) (By similarity). After acrosome reaction localizes to the equatorial segment region in both noncapacitated and capacitated, acrosome-reacted sperm (By similarity).
Protein: RLMN_CHLTE
Sequence: MEKNEISEERRTQEKEKQHGHRLNIRRLGRKELTELLTRLGEPAYRANQLHRWLYSNQALRFEEMSTLSKQLRQKLASEWIIHPASLVGTERETTDASLVTGNPTAKFLIKLEDNELVESVLIPSEERITACISSQIGCPLRCTFCATGHMGFRRNLTASEITDQVFLLEKEAQKRHWRGLTNIVFMGMGEPLLNLDNVLESIGTLTEKDYQFSISERKITISTVGLPVEMDRIARSGLKTKLAISLHSADQLIRERMMPIAADITLDKLAKAINSYNSVTSQPVTLVYMLLEGINDSPEDARKLVRFAKRVLCKINLIDYNSIVTLKFKPGCSSSKTMFIQQLLDAGLLVTVRKSQGATINAACGQLATRPVR
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMA_BURP6
Sequence: MYKLVLIRHGESTWNKENRFTGWVDVDLTEQGNREARQAGQLLKEAGYTFDIAYTSVLKRAIRTLWHVQDQMDLMYVPVVHSWRLNERHYGALSGLNKAETAAKYGDEQVLVWRRSYDTPPPALEPGDERAPYADPRYAKVPREQLPLTECLKDTVARVLPLWNESIAPAVKAGKQVLIAAHGNSLRALIKYLDGISDADIVGLNIPNGVPLVYELDESLTPIRHYYLGDQEAIAKAQAAVAQQGKSAA
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: Y102_MYCTU
Sequence: MGTHGATKSATSAVPTPRSNSMAMVRLAIGLLGVCAVVAAFGLVSGARRYAEAGNPYPGAFVSVAEPVGFFAASLAGALCLGALIHVVMTAKPEPDGLIDAAAFRIHLLAERVSGLWLGLAATMVVIQAAHDTGVGPARLLASGALSDSVAASEMARGWIVAAICALVVATALRLYTRWLGHVVLLVPTVLAVVATAVTGNPGQGPDHDYATSAAIVFAVAFATLTGLKIAAALAGTTPSRAVLVTQVTCGALALAYGAMLLYLFIPGWAVDSDFARLGLLAGVILTSVWLFDCWRLLVRPPHAGRRRGGGSGAALAMMAAMASIAAMAVMTAPRFLTHAFTAWDVFLGYELPQPPTIARVLTVWRFDSLIGAAGVVLAIGYAAGFAALRRRGNSWPVGRLIAWLTGCAALVFTSGSGVRAYGSAMFSVHMAEHMTLNMFIPVLLVLGGPVTLALRVLPVTGDGRPPGAREWLTWLLHSRVTTFLSHPITAFVLFVASPYIVYFTPLFDTFVRYHWGHEFMAIHFLVVGYLFYWAIIGIDPGPRRLPYPGRIGLLFAVMPFHAFFGIALMTMSSTVGATFYRSVNLPWLSSIIADQHLGGGIAWSLTELPVIMVIVALVTQWARQDRRVASREDRHADSDYADDELEAYNAMLRELSRMRR
What are the official names of this protein?
Uncharacterized protein Rv0102.
What is the protein family that this protein belongs to?
To M.leprae ML1998.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HSLV_DICNV
Sequence: MFDAHSTTILSVRRGNHVAIAGDGQVSLGQTIMKGNARKIRRLYHDQILAGFAGATADAFTLFELFEGKLEAQDGQLLRAAVEMAKEWRTDRSLRRLEAMLIVADRNNTLILSGNGDIVEPENSLAAIGSGGMYALAAARALYHNTEMDALSIAEKSLNIAADICIYTNHNIVSDELKDA
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SE1L2_RAT
Sequence: MNPLALLVEILIIIEVTTKNSEAERYNRKQKEVNVTTQVSVSKVKQFLSHLLEQGKANKIANKRENPLEKKKHQHKLKIKGIQNKNLLKRNQNYFKKPAKKSITDKGDELFKMGNKILQESKSQKQKTEAYTFFTRAADMGNLKAMEKMADALLFGSFGMQNITAAIQLYESLAKEGSYKAQNALGFLSSYGIGMEYDQAKALIYYTFGSAGGSMMSQMILGYRYLSGINVLQNCEVALNHYKKVADYIADKLEKSEGIPVEKVRLTERPENLSSNSEILDWDIYQYYKFLAERGDVQIQVSLGQLHLIGRKGLDQDYSKALYYFLKAAKAGSANAMAFIGKMYLEGNAAAPQNNATAFKYFSMAASKGNAIGLHGLGLLYFHGKGVPVNYGEALKYFQKAAEKGWPNAQFHLGFMYYSGSGVWKDYKLAFKYFYLASQSGQPLAIYYLAEMYATGTGVLRSCRTAVEPYKGVCELGHWAEKFLTAYFAYKDGDVDSSLIQYALLAEMGYEVAQSNSAFILESKKAKILGKEKMYPMALLLWNRAAIQGNAFARVKIGDYHYYGYGTKKDYETAATHYSIAADKHHSAQAMFNLAYMYEHGLGIAQDIHLARRLYDMAAQTSPDAHIPVFFALMKLETMHFLQDILFFNFTTKWKWLKLDSTIGPYWDLLVIGLIVVVLIFLLRNHHR
What are the official names of this protein?
Protein sel-1 homolog 2, Suppressor of lin-12-like protein 2, Sel-1L2.
What is the protein family that this protein belongs to?
Belongs to the sel-1 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RT25_AJECN
Sequence: MGRYNLTALRVRRTALATTQCGKPGTRQPWLDVLADIPPASILVRNQAPSHPVVKQRMRTVPGKSKPQLEIKSSAGRKQTSKKPSRIFQPKEIRYEEDQLRKEFFRDHPWELARPRVVLENDGNDHRRYNWQNIQQPGKKLDGESVVQRQLYLLNNVPDMSKGAAYEIARREFYQLRLQEDVERRVAQEEALATGAYFGPDMHTVGMELENQEYEKWKVWAEGENQAMEQRLAAFTGSTGPTEESGESEDEIPLIEEEDAIGASEESETEAPSGPPI
What are the official names of this protein?
37S ribosomal protein S25, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mS23 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ARP19_HUMAN
Sequence: MSAEVPEAASAEEQKEMEDKVTSPEKAEEAKLKARYPHLGQKPGGSDFLRKRLQKGQKYFDSGDYNMAKAKMKNKQLPTAAPDKTEVTGDHIPTPQDLPQRKPSLVASKLAG
What is the function of this protein?
Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.  When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase.  May indirectly enhance GAP-43 expression.
What are the official names of this protein?
cAMP-regulated phosphoprotein 19, ARPP-19.
What is the protein family that this protein belongs to?
Belongs to the endosulfine family.
What are the subcellular locations of this protein?
Cytoplasm.