PharMolix/UniProtQA huggingface dataset:
Protein: HMUV_SODGM
Sequence: MSDALLHADNLHYRAGGRTLIEGVSLTLAPGEMVALIGPNGAGKSTLLRLLSGYLDPIQGQCRLQGRELAVWTAAQLARRRAVMAQQGSVAFSFRVSEVVAMARAPWSGTPATTVLAEVMTLTGCEMLASREFRRLSGGEQQRVRLAMALAQLWQQDGPEGWLFLDEPTSALDLYHQQALLRLLYQLTRAGKLAVCCILHDVNLAALWADRILLLQQGRLAASGTPAEVLTEVQLRACYQADLRVQTQQEDGVPQIYLRR
What is the function of this protein?
Part of the ABC transporter complex HmuTUV involved in hemin import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Hemin import ATP-binding protein HmuV.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Heme (hemin) importer (TC 3.A.1.14.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SOMA_SCIOC
Sequence: MDRVLLLLSVLSLGVSSQPITDSQRLFSIAVSRVQHLHLLAQRLFSDFESSLQTEEQRQLNKIFLQDFCNSDYIISPIDKHETQRSSVLKLLSISYRLVESWEFPSRSLSGGSAPRNQISPKLSDLKTGILLLIRANQDGAEIFPDSSTLQLAPYGNYYQSLSGDESLRRTYELLACFKKDMHKVETYLTVAKCRLSPEANCTL
What is the function of this protein?
Growth hormone plays an important role in growth control and is involved in the regulation of several anabolic processes.  Implicated as an osmoregulatory substance important for seawater adaptation.
What are the official names of this protein?
Somatotropin, Growth hormone.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: EF1B_METLZ
Sequence: MGEVVVILKIMPESPDVDLEKLQADIRAKVSGIEDMKVEPIGFGLSAIKIAMITEDDEGAGDKIEGLFSQIPGIDRTEIESLNRLL
What is the function of this protein?
Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
What are the official names of this protein?
Elongation factor 1-beta, EF-1-beta, aEF-1beta.
What is the protein family that this protein belongs to?
Belongs to the EF-1-beta/EF-1-delta family.
Protein: DCUP_COXBN
Sequence: MLRLKNDRFIRALLRQPVDRTPVWIMRQAGRYLPEYRQLREKVPNFMAFCKTPELACEATLQPLRRFPLDAAIIFSDILTIPDAMGVDLHIAPTVGPVIRNPVRSAQDVNRLQMPAVEEALSYLFDAIRLTVKALDHRVPLIGFAGSPWTLACYMTEGQSSKTFLTARAMLYQQPDVFHTLLQKLTTLTIAYLNAQIKAGADVVMLFDTWGGLLTPSLYRQFSLDYLSQIAAEVVRQKNGRKIPLIFFTKNGGQWLESIANSGCDAVGLDWTTDIGQARRRVGDRVALQGNLDPAILLSNPESISTAAVDILKSYGQGSGHVFNLGHGIDPSTPIENVAALVEAVQNFSIKNEEPINSYYR
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA_WOLPP
Sequence: MHKILVRSNHKPLIGKIKINGSKNAVLPIMAASLFSNSSITLHNVPDLIDVHLMSELLKSLGAEVNFICNKDYKANHTLEIDCSNINNHLISHEIASRLRASFLMLGPMLSRFGRVSTVFPGGCNIGKRPVDIHIKALEAMGAKIEIDSCNITATTKGKLQGKEITFEKVSVGATENIIMSATLAEGVTTINNAATEPEVLDLIEFLKIMGANIEVNNTKITIEGVEALNGCEHKIIPDRIEAGTYALAAIITDGELKLEGVSLSDIECIANELKTIGARVELHDDGIIISRKNGSIKSAHVATNPYPNFPSDMQPQLMSAMSIAGGISIIEENVFESRFAHANELRKLGANISIEKNKATISGIKSLSGANLHANDLRSTAALILASLVAKGETTINNSHHLWRGYEAMHEKLNSCGADIFVSS
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_MYCTA
Sequence: MAVGVSPGELRELTDEELAERLRESKEELFNLRFQMATGQLNNNRRLRTVRQEIARIYTVLRERELGLATGPDGKES
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: RL24_ICTPU
Sequence: MKVELCSFSGYKIYPGHGPVYARIDGKVFQFLNAKCESAFLTKRNPRQINWTVLYRRKHKKGQSEEVTKKRTRRAVKFQRAITGASLAEILAKRNQKPEVRKAQREQAIRAAKEAKKAKQATKKVSTQSTKAPAKAAPKQKIAKPMKVSAPRVGGKR
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL24 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSP_PLAMA
Sequence: MKKLSVLAISSFLIVDFLFPGYHHNSNSTKSRNLSELCYNNVDTKLFNELEVRYSTNQDHFYNYNKTIRLLNENNNEKDGNVTNERKKKPTKAVENKLKQPPGDDDGAGNDAGNDAGNDAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNDAGNAAGNAAGNAAGNAAGNAAGNDAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNDAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNAAGNEKAKNKDNKVDANTNKKDNQEENNDSSNGPSEEHIKNYLESIRNSITEEWSPCSVTCGSGIRARRKVGAKNKKPAELVLSDLETEICSLDKCSSIFNVVSNSLGIVLVLVLILFH
What is the function of this protein?
In the vertebrate host, binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes and is required for sporozoite invasion of the host hepatocytes.
What are the official names of this protein?
Circumsporozoite protein, CS.
What is the protein family that this protein belongs to?
Belongs to the plasmodium circumsporozoite protein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Cytoplasm. Note=Localizes to the cytoplasm and the cell membrane in oocysts at day 6 post infection and then gradually distributes over the entire cell surface of the sporoblast and the budding sporozoites.
Protein: MACB2_PSESM
Sequence: MNQKVDIEALHETSINSDQPLLRLQQVSRSFMAGDREFQVLKHIDLAIHTGELVAIIGASGSGKSTLMNILGCLDHASAGSYQVNGQETRELDDDALAALRRDHFGFIFQRYHLLPHLDAVRNVEIPAIYAGTAQTTRHERAQALLTRLGLGGHLQHRPSQMSGGQQQRVSIARALMNGGQVILADEPTGALDTASGKEVMRTLLELHAAGHTVILVTHDPKVAANAERIIEVSDGEIISDRRTAQTTQPAPEAQPATPPGPAPRRLLASLGLFREAFNMAWIALISHRMRTLLTMLGIIIGITSVVSISAIGEGAKRYVLKDIQSIGSNTIDIYAGANFGDSRAKSIETLLPSDVAALNQLYYIDSATPVVGRSMLVRYRNVDVDAQLNGVSSRYFQVRNIQLAAGITFSDQDARRQAQVVVLDHNTAQRLFGPGVNPLGQVILVGKLPCTVIGVTSDHKNLFIAGNTLNLWMPYETAAGRVLGQRHLDSISVRVKDGMPSKAVEEQIKALMLQRHGTKDFFTNNLDSVMQTVQKTSRSLTLLLSLIAVISLVVGGIGVMNIMLVSVTERTREIGIRMAVGARQSDIRQQFLVEAVMVCLMGGVIGIGLSYAIGYLFTLFVQQWEMVFSLASVVTAFACSTLIGVLFGFVPARNAARLDPIEALARD
What is the function of this protein?
Part of the tripartite efflux system MacAB-TolC.  MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation.  Confers resistance against macrolides.
What are the official names of this protein?
Macrolide export ATP-binding/permease protein MacB 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PRZN_SERME
Sequence: MQSTKKAIEITESNFAAATTGYDAVDDLLHYHERGNGIQINGKDSFSNEQAGLFITRENQTWNGYKVFGQPVKLTFSFPDYKFSSTNVAGDTGLSKFSAEQQQQAKLSLQSWADVANITFTEVAAGQKANITFGNYSQDRPGHYDYGTQAYAFLPNTIWQGQDLGGQTWYNVNQSNVKHPATEDYGRQTFTHEIGHALGLSHPGDYNAGEGNPTYRDVTYAEDTRQFSLMSYWSETNTGGDNGGHYAAAPLLDDIAAIQHLYGANLSTRTGDTVYGFNSNTGRDFLSTTSNSQKVIFAAWDAGGNDTFDFSGYTANQRINLNEKSFSDVGGLKGNVSIAAGVTIENAIGGSGNDVIVGNAANNVLKGGAGNDVLFGGGGADELWGGAGKDIFVFSAASDSAPGASDWIRDFQKGIDKIDLSFFNKEAQSSDFIHFVDHFSGAAGEALLSYNASNNVTDLSVNIGGHQAPDFLVKIVGQVDVATDFIV
What is the function of this protein?
Naturally present in the silkworm intestine and allows the emerging moth to dissolve its cocoon.
What are the official names of this protein?
Serralysin, Extracellular metalloproteinase, Serratiopeptidase, Serrapeptase, Serrapeptidase, Zinc proteinase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M10B family.
What are the subcellular locations of this protein?
Secreted.
Protein: UPP_XANC8
Sequence: MKIVEVRHPLVQHKIGLLRDAALSTKGFRELVTELGTLLAYEATANLDTESHVQPGWAGPVEVQRIAGAKITLVPILRAGLGMLPGVLALIPAARVSVVGLQRDEETLQPVPYFERLTGRLEERDALILDPMLATGGTLIATIDMLKRAGARRIKGIFLVAAPEGLKALEAVHPDVEVYTAAIDDHLNEKGYILPGLGDAGDRIFGTRVE
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: HIS1_PROA2
Sequence: MSASKQLLKLGLPKGSLQDSTLDLFAKAGFHFSVKSRSYFPSIDDDELEAILIRAQEMAHYVELGAFDVGLTGKDWIIETDADVVEVSDLVYSKASMRPVRWVLAVPESSSIQTVKDLEGKHIATEVVNITKKYLAENNVNAHVEFSWGATEVKPPELADAIVEVTETGSSLRANKLRIVEVLLESNTKLIANRNSWNDPWKREKIENMAMLLQGAIHAQGKVGLKMNAPKDALDKIMAFIPGLRTPTVSNLADDKWVALEVIVDEQTVRSVIPDLKRAGAEGIFEYHINKLID
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE_SALTY
Sequence: MKIKTRFAPSPTGYLHVGGARTALYSWLFARHHGGEFVLRIEDTDLERSTPEAIEAIMDGMNWLNLEWDEGPYFQTKRFDRYNAVIDEMLEAGTAYKCYCSKERLEQLREDQMAKGEKPRYDGRCRHSHEHHADDEPCVVRFANPQDGSVIFDDQIRGPIEFSNQELDDLIIRRTDGSPTYNFCVVVDDWDMEITHVIRGEDHINNTPRQINILKALNAPVPMYAHVSMINGDDGKKLSKRHGAVSVMQYRDDGYLPEALLNYLVRLGWSSGDQEIFTREEMIKLFSLGAVSKSASAFNTDKLLWLNHHYINTLAPEYVATHLQWHIEQENIDTRNGPQLAELVKLLGERCKTLKEMAQSCRYFYEDFSEFDADAAKKHLRPVARQPLEVVRDKLSAITDWSAENVHHAIQATADELEVGMGKVGMPLRVAVTGAGQSPALDVTVHAIGKTRSIERINKALGFIAERESQQ
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDM34_ASPTN
Sequence: MAFNFNWSPLMADASFYTRAQDLLTAALNKSPKPPIIVDDIIVTELNLGSIPPELEILEIGDLAEDRFRGIFKMSYSGDAFLTLKTRVQANPLNTYLLTRPSFASPLPLAAATPLTIPLQITLSDFKLSGFVILVFSKQKGITVVFRNDPLESLKVSSTFDSIPFVRDFLQREIEAQLRILFMDELPAIIHRLSLRLWVPEYRAGEEDQDQNTNTAGEGPGQDPLASPPQDPVDALGNALNESEIASLSLDSSVETHSLFSQKNLLRLAALTDSQRTLSLFTPSIQEVVYRAWTSPSDQGDISGGVTSPLSPALSRTQSQVGGMSSFQDNASTISSYSRTSTSTHTFSTYGLNLGAGRHSKAHARKRKKRVVDLRRPKQPESETASVTDESSFTETTSAPSVRSAPLPRVNEQPDDPVTPPLSPDSDFHLPPIPERHRFSISRPALRRDIATEMLRETGESSSEPARRHAEVDDIDATPRTIIRHEPSRYEGEKQEAGPSRQLPSTILPFTEEKSTPGPVDQALVERIAGEIARRMREDKLMGTNSCAFWNRPGHEESPPPAYGQ
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  Mdm34 is required for the interaction of the ER-resident membrane protein mmm1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 34.
What is the protein family that this protein belongs to?
Belongs to the MDM34 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria- endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: SODC5_MAIZE
Sequence: MVKAVAVLGSSDGVKGTIFFTQEGDGPTAVTGSVSGLKPGLHGFHVHALGDTTNGCMSTGPHYNPASKEHGAPEDENRHAGDLGNVTAGADGVANINVTDSQIPLTGPNSIIGRAVVVHADPDDLGKGGHELSKSTGNAGGRVACGIIGLQG
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn] 4AP.
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SBLE_STABO
Sequence: MLALFFSLAPLLSQALPLGYTAAPAESFYFWPENISSLQAGEIFRKRELLTLPDIFDFGPNLEKVVQVAYKTRLTDGNDSFSIASIFIPKNPSPELKLYSYQTFEDAVQLDCAPSYALEVGNKSSNYLPVTSNLSAISRELEKGRHCIIPDHEGYISGFFAGRQEGYAGLDGIRAARNYLNGTNETPIGIFGYSGGAQATAWIVDLHDEYAPDLNFVGTVSGGTLVDAWGTFQYIDYPKVYLKGSILIMYTGLFSGYPAQFEVIWPYIEPVIQENMLLLRLAPNDCNQSPILQGYNNSIMAGIHVDLPEFPASKYIFQHESLLANYSVVPVSTPKFPRYMYHGGSDELAKLSLVEQYVDQQWNTGANLTFVVYPGLLHDETAYRGFDAAMDWLDAQLDSGYLPPVNSTHT
What is the function of this protein?
Responsible for the lactonization of acidic sophorolipids (SLs).  Catalyzes the intramolecular esterification (ring closure) between the carboxyl group of the hydroxy fatty acid and the hydroxyl group of sophorose C6'' of acidic SLs.  Lactonizes acetylated acidic SLs, producing di-acetylated C18:2, C18:1 and C18:0 lactonic SL, and mono-acetylated C18:1 lactonic SL.  Does not catalyze the reverse reaction, the hydrolysis of lactonic SL into acidic SL, nor hydrolysis of triglycerides or paranitrophenyl esters.
What are the official names of this protein?
Lactone esterase, SBLE, Lactonase, Lipase-like enzyme SBLE.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: ERG20_GANLU
Sequence: MADAKAQKRQKFDNVFPKLREELLAYLNQEGMPQDAVSWFQRNLDYNVPGGKLNRGISVVDSVEILKGRKLNDDEYFKAALLGWCVEFLQAFFLVSDDMMDQSVTRRGQPCWFRVEGINLIAINDSFMLEGAIYYLLKKHFRSEPYYVHLLELFHDTTFQTEIGQLIDLITAPEDHVDLSKFSLAKHQKIVIYKTAYYSFYLPVALAMYTCGVPHAPANDPYALAQSILIPLGEYFQVQDDFLDFAAPPEVLGKVGTDIVDNKCSWCVNAALARASPAQRRVLDDNYGLKDKEAEARVKALYEELGIRDEFAAYEERAYARIVGLIETIPAEGADVGAGDVRLKREVFKAFLDKIYKRQK
What is the function of this protein?
Farnesyl pyrophosphate synthase; part of the second module of ergosterol biosynthesis pathway that includes the middle steps of the pathway (By similarity).  The second module involves the formation of farnesyl diphosphate, which is also an important intermediate in the biosynthesis of ubiquinone, dolichol, heme and prenylated proteins (By similarity).  This module also plays a key role in the biosynthesis of triterpenes such as ganoderic acids (GA), a group of highly oxygenated lanostane-type triterpenoids which are well recognized as a main group of unique bioactive compounds in the medicinal mushroom Ganoderma lucidum (PubMed:22203490, PubMed:31253150).  Activity by the mevalonate kinase first converts mevalonate into 5-phosphomevalonate (By similarity).  5-phosphomevalonate is then further converted to 5-diphosphomevalonate by the phosphomevalonate kinase (By similarity).  The diphosphomevalonate decarboxylase MVD then produces isopentenyl diphosphate (PubMed:22203490).  The isopentenyl-diphosphate delta-isomerase then catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity).  Finally the farnesyl diphosphate synthase FPS catalyzes the sequential condensation of isopentenyl pyrophosphate with dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate (PubMed:18540102, PubMed:31253150).
What are the official names of this protein?
Farnesyl pyrophosphate synthase, FPP synthase, FPS, (2E,6E)-farnesyl diphosphate synthase, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Geranyltranstransferase.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
Protein: CCSA_HELAN
Sequence: MIFSTLEHILTHISFSIVSIVITLHLITLLGNEIIKPYDSSEKGMIATFLCLTGLLTTRWIYSGHFPLSDLYESLIFLSWSFSLIHIVPYFKIRKNDLTTITASITIFTQGFATSGLLNEIHKPTILVPALQSEWLIMHVSMMILSYAALLCGSLLSVALLVITFRNIFYSSKSNNLLKLNESFSFGEIQYKNERNNIFQKTSFFSDKNYYKAQFIQQLDYWSYRVISLGFIFLTIGILSGAVWANEAWGSYWSWDPKETWAFITWIVFAIYLHTRTNKNLQGANSAIVATLGFLIIWICYFGVNLLGIGLHSYGSFTLTYS
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: VP3_ROTHK
Sequence: MKVLALRHSVAQVYADTQTYLHDDSKDEYENAFLISNLTAHNILYLNYSLKTLKILNKSGIAAVETQSPDELFALIRCNFTYDYENNIVYLHDYSYYTNNEIRTDQHWITKTDIIDYLLPGWKLTYVGYNGKNTRGHYNFSFSCQNAATDDDIIVEYIYSNELDFQNFMLRKIKERMTTSLPIARLSNRVFRDKLFPSIANMHKRVINVGPRNESMFTFLNFPTIKQFSNGAYIVKHTIKLKQEKWLGKRVSQFDIGQYKNMLNVVTTIYYYYNLYHSKPIIYMLGSAPSYWIYNVKQYSDFTFETWDPVDTPYSTTHHKELFFDKDVMKLKDDSVLYIDIRTDRKNMDWKEWRKVVEQQTVSNLNIAYNYLSTGKAKVCCVKLTAMDLELPITAKLLHHPTTEVRSEFYAILDVWDIITIKRFIPKGVFYAFINNITTENVFIQPPFKLKASPTDYIVALYALSNDFNSRQDVINLINKQKQSLITVRINNTFKDEPKVNFKNIYDWTFLPTDFELKDSVITSYDGCLGMFGLSLSLSSKPTGNNHLFIINGTDKYYKLDQYANHMGISRRSHQIRFSESATSYSGYIFRDLSNNNFNLIGTNVENSVSGHVYNALIYYRYNYAFDLKRWIYLHSIGKVAVEGGRYYEHAPIELIYACRSAREFAILQDDLTVLRYANEIEGYINKVYSITYADDPNYFIGITFNNIPYEYDVKVPHLTLGVLFISDNMIDEVVAVLKEMKTELFKTEISTSYNYMLFDNVYVANASGVLSTYFKLYNMFYRNHITFGQSRMFIPHITLSFSNKRTIRIESTRLKINSIYLRKIRGETVFDMSE
What is the function of this protein?
Counteracts the host innate immune response thanks to its phosphodiesterase that degrades the 5'-triphosphorylated, 2'-5' linked adenylate oligomers produced by the host cell IFN-inducible 2',5'-oligoadenylate synthetase (OAS).  The host RNaseL is therefore not activated.
What are the official names of this protein?
Protein VP3.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP3 family.
What are the subcellular locations of this protein?
Virion. Note=Attached inside the inner capsid as a minor component. There are about 11 to 12 copies per virion.
Protein: RL27_LARHH
Sequence: MAHKKAGGSSRNGRDSQAKRLGTKVYGGELIPAGSIIIRQRGTRFHAGENVGMGKDHTLFAKVDGYVKFVVKGALKRKTVIVEQYTGEAA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: Y966_MYCTO
Sequence: MSNSAQRDARNSRDESARASDTDRIQIAQLLAYAAEQGRLQLTDYEDRLARAYAATTYQELDRLRADLPGAAIGPRRGGECNPAPSTLLLALLGGFERRGRWNVPKKLTTFTLWGSGVLDLRYADFTSTEVDIRAYSIMGAQTILLPPEVNVEIHGHRVMGGFDRKVVGEGTRGAPTVRIRGFSLWGDVGIKRKPRKPRK
What are the official names of this protein?
Uncharacterized protein MT0994.
Protein: COXX_METC4
Sequence: MTSLSNSLSADTGTTSFSPAAGGEVSDFFALLKPRVMVLVIFTALVGMVVSDATVNPVIAAISLLMIAVGAGASGCLNMWWDADIDALMTRTAKRPIPDGRIRPDEALAFGIVLSVGSVLILGLASNWLAAGLLAFTIVFYAVIYSMWLKRATAQNIVIGGAAGALPPVVGQAAVTGHVGIESLVLFAIIFIWTPPHFWALALVKSGEYARAGIPMMPNVAGPDSTRRQIIWYSLVLAPLALLPVWLGFGGWLYAVVGVLGGLGMLAGAVQVYRLREGEPERKAAMGLFAFSILYLFLLFSALLAEQGLGLFRAVAA
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYB_COLCO
Sequence: MPNQHTLLLFNLLPVGSNISTWWNFGSMLLTCSALQVMTGFFLAIHYTANINLAFSSIVHITRDVPYGWIMQNLHAIGASMFFICIYIHIARGLYYGSYLNKNVWLSGTTLLIILMATAFFGYVLPWGQMSFWAATVITNLLTAVPYIGTALTTWLWGGFSINDPTLTRFFALHFILPFAIISMSSIHIMLLHTEGSSNPLGTNSDIDKIPFHPYHSHKDILMLTIMITTMFTIMSFSPDIFNDPENFSKANPLVTPQHIKPEWYFLFAYGILRSIPNKLGGTVALVLSVAILMTMPFTHTSYIRSMAFRPIMQLVFWTLIATFITITWAATKPVEPPFTIIGQTTSFLYFSFFIMNPLVGWLENKISFHS
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: YFBU_ECODH
Sequence: MEMTNAQRLILSNQYKMMTMLDPANAERYRRLQTIIERGYGLQMRELDREFGELKEETCRTIIDIMEMYHALHVSWSNLQDQQSIDERRVTFLGFDAATEARYLGYVRFMVNVEGRYTHFDAGTHGFNAQTPMWEKYQRMLNVWHACPRQYHLSANEINQIINA
What are the official names of this protein?
UPF0304 protein YfbU.
What is the protein family that this protein belongs to?
Belongs to the UPF0304 family.
Protein: YL169_YEAST
Sequence: MLKFKNMYITSHDNFIAYIFFTFFTFIPFYRSDQSTLCRCSQKIFLSGQRLLRQTVIIVGPLAPFSSYSSPFFFIPLFFSGPNSIPFQDYRCSPWCPSRSHGAVLPSYCSLRWSHRT
What are the official names of this protein?
Putative uncharacterized protein YLR169W.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CAIB_SALTI
Sequence: MNHLPMPTFGPLAGVRVVFSGIEIAGPFAGQMFAEWGAEVIWIENVAWADTIRVQPNYPQLSRRNLHALSLNIFKDEGREAFLKLMETTDIFIEASKGPAFARRGITDEVLWEHNPKLVIAHLSGFGQYGTEEYTNLPAYNTIAQAFSGYLIQNGDVDQPMPAFPYTADYFSGMTATTAALAALHKVRETGKGESIDIAMYEVMLRMGQYFMMDYFNGGEICPRMTKGKDPYYAGCGLYKCADGYIVMELVGITQINECFKDIGLAHILGTPEVPEGTQLIHRVECPYGPLVEEKLDAWLAAHTIADVQARFAELNIACAKVLTIPELEGNPQYVARESITQWQTMDGRTCKGPNIMPKFKNNPGKIWRGMPSHGMDTAAILKNIGYSEADIKELVGKGLAKVED
What is the function of this protein?
Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine.  Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA (By similarity).
What are the official names of this protein?
L-carnitine CoA-transferase, Crotonobetainyl-CoA:carnitine CoA-transferase.
What is the protein family that this protein belongs to?
Belongs to the CoA-transferase III family. CaiB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROQ_ECO55
Sequence: MENQPKLNSSKEVIAFLAERFPHCFSAEGEARPLKIGIFQDLVDRVAGEMNLSKTQLRSALRLYTSSWRYLYGVKPGATRVDLDGNPCGELDEQHVEHARKQLEEAKARVQAQRAEQQAKKREAAAAAGEKEDAPRRERKPRPTTPRRKEGAERKPRAQKPVEKAPKTVKAPREEQHTPVSDISALTVGQALKVKAGQNAMDATVLEITKDGVRVQLNSGMSLIVRAEHLVF
What is the function of this protein?
RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities.  May regulate ProP activity through an RNA-based, post-transcriptional mechanism.
What are the official names of this protein?
RNA chaperone ProQ.
What is the protein family that this protein belongs to?
Belongs to the ProQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPF_PYRAR
Sequence: MPLVKICGVANVEDAAALDGLVEYIGFILEPSSPRSVKPEGLGALRDAVKKSRPVLVTASLPPKTAVDIAAENDIPVVQHHSLLAPEDFDYANSRGVAVAPVATYRPGTELRPLVERLLKTPHEYVLVDADKKSQERYEGGLKIPLALLAEVAPLGKVALAGGITPENAPLVAKLNPYMIDVASGVEASPGVKDMAKVRALLKAVGRL
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.