PharMolix/UniProtQA huggingface dataset:
Protein: GLMU_STRZT
Sequence: MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQPEKTVTVVGHKAELVEEVLTGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGDTPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATDFEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLKDFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEANVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPNSSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKYKTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYATRLPHHPKNQ
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLD7_YEAS6
Sequence: MSRKLCTLNFTLSGKQGSLVIRDIQLWSNRPTASKSTSELRGQFIQYVDLAKLPLWVRSTNMNTYRCYSTSATAQAYFKSKLRNANRGIVIELSDKVDQRSQEPAYLIIFRENTELNCFQVDLTMKHEFDGQVTKLKQEIGKTRASVSKEGSIDIIIQQSQQRKIGTKTKVYRNVHINDKRLQFNETLSKLILGGLRLRGISNSITDYQKLYKITFDAAEFTHRDELKRISMGSGEEVSFESLQETVETLLKLFTKS
What is the function of this protein?
Required for the proper function of SLD3 at the initiation of DNA replication.  Binds to SLD3 and reduces its affinity for CDC45, a component of the replication fork.  Required for mitochondrial morphology (By similarity).
What are the official names of this protein?
Mitochondrial morphogenesis protein SLD7, Synthetic lethality with DPB11-24 mutation protein 7.
What is the protein family that this protein belongs to?
Belongs to the SLD7 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle pole.
Protein: RS8_CERS1
Sequence: MSVNDPLGDMLTRIRNAQLRGKSTVSTPASRLRAWVLDVLQAEGYIRGYEKKETENGQGELVISLKYFEGTPVIRELKRVSKPGRRVYMATKDLPSVRNGLGVSIISTPKGVMSDASARSANVGGEVLCTVF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RNAS1_OSPRU
Sequence: ETPAEKFQRQHMDTEHSTASSSNYCNLMMKARDMTSGRCKPLNTFIHEPKSVVDAVCHQENVTCKNGRTNCYKSNSRLSITNCRQTGASKYPNCQYETSNLNKQIIVACEGQYVPVHFDAYV
What is the function of this protein?
Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides.  Acts on single-stranded and double-stranded RNA (By similarity).
What are the official names of this protein?
Ribonuclease pancreatic, RNase 1, RNase A.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: NAGB_MANSM
Sequence: MRLIPLKNDEQVAKWSAQHIVDRINAFNPTEDHPFVLGLPTGGTPLKTYRELIKLYQAGKVSFKHVVTFNMDEYVGLPKEHPQSYHSFMYNNFFNHVDIPEKNINILDGNTPDHDAECRRYEEKIKSYGKINLFMGGVGVDGHIAFNEPASSLSSRTRIKTLTPDTLIANSRFFNNDVSQVPKYALTIGVATLLDAEEVMLLITGHQKALALQACVEGAVNHLWTVSALQLHRHSIVVCDEPATQELKVKTVKYFTELEAYAIHSVI
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: RS9_XANP2
Sequence: MAEVLQSLDALGAANVAAVQPDAPVHVQKLDKYGRAYATGKRKNAVARVWVRPGTGKVTINDRDIEVYFARPVLRLMINQPFQAAAREGQYDVVCTVSGGGLSGQAGAVRHGISKALTYYEPELRSPLKKGGFITRDSRVVERKKYGRAKARRSFQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: RS16_ECO57
Sequence: MVTIRLARHGAKKRPFYQVVVADSRNARNGRFIERVGFFNPIASEKEEGTRLDLDRIAHWVGQGATISDRVAALIKEVNKAA
What is the function of this protein?
In addition to being a ribosomal protein, S16 also has a cation-dependent endonuclease activity.
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: Y4187_BACHK
Sequence: MNGIRDVVKEEQPRERLLLEGAGSLSNRELLAVLLRTGSKEESVLKLSDKILHHFDGLRMLKDATLEELVSIHGVGVAKATQLIAAFELGRRMVRLEYQNRYSIRSPEDCATYMMEEMRFLQQEHFVCLYLNTKNQVIHRQTIFIGSLNSSIVHPREVFKEAFRRAAASIICLHNHPSGDPAPSREDIEVTKRLVECGRIIGIEVLDHIIIGDHKFVSLKEKGHI
What are the official names of this protein?
UPF0758 protein BT9727_4187.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: SST_STRMK
Sequence: MTEFIPPGTRFHALPSPFPFKRGGALHGARVAYETWGTLAADASNAILIVTGLSPDAHAAANDANPAAGWWEGMVGPGKAIDTDRWFVVCVNSLGSCKGSTGPASLNPATGQPYRLDFPELSIEDGARAAIEVVRALGIEQLACVVGNSMGGMTALAVLMLHPGIARSHVNISGSAQALPFSIAIRSLQREAIRLDPRWNGGHYDDDAYPESGMRMARKLGVITYRSALEWDGRFGRVRLDSDQTDDDPFGLEFQVESYLEGHARRFVRFFDPNCYLYLSRSMDWFDLAEYADGDVLAGLAKIRVEKALAIGANTDILFPVQQQQQVADGLRAGGADAHFIGLESPQGHDAFLVDFDRFGPAVRGFLDAL
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-serine, forming succinyl-L-serine.
What are the official names of this protein?
Serine O-succinyltransferase, SST.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KUNPG_ORNMO
Sequence: SDDKCQGRPMYGCREDDDSVFGWTYDSNHGQCWKGSYCKHRRQPSNYFASQQECRNTCGA
What is the function of this protein?
Tick salivary platelet aggregation inhibitor that plays an important part in the anti-hemostatic strategy of ticks (PubMed:8120028).  Inhibits fibrinogen interaction with platelets (PubMed:8120028).  Acts by binding (in a divalent metal ion dependent manner) to the glycoprotein IIb-IIIa receptor (ITGA2B/ITGB3) on the platelet surface and inhibits aggregation induced by ADP (IC(50)=99-104 nM), thrombin, collagen (IC(50)=64 nM) platelet-activating factor and collagen (PubMed:8120028, PubMed:9434779, PubMed:33537548).  Interacts to unstimulated platelets (Kd=42. 5 nM) and to ADP-stimulated platelets (Kd=39. 4 nM) (PubMed:8120028).  In contrast to many disintegrins which only interact with the beta-3 subunit, interacts with the two subunits (alpha-IIb and beta-3) (PubMed:8120028, PubMed:9434779).  Under flow conditions, reduces and delays platelet adhesion, aggregation, and fibrin formation (PubMed:33537548).
What are the official names of this protein?
Disagregin, Antihemostatic agent, Platelet aggregation inhibitor, PAI.
What are the subcellular locations of this protein?
Secreted.
Protein: PSBJ_GUITH
Sequence: MASTGRIPLWIIATFGGIAALTVVGLFIYGSYSGIGSAL
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein J, PSII-J.
What is the protein family that this protein belongs to?
Belongs to the PsbJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: DEGP_BUCAI
Sequence: MKKSAIILSKIILILTLLLSFGMSWNNVFSNTKNSIVSREISPSLAPMLEKVMPSVISINIEGSAITRTSRLPHQFQPFFGDNSPFCQGNSPFRHSPFCHINPDSDDKKEKFRALGSGVIINADKGYAVTNNHVVENANKIQVQLSDGRRYEARVIGKDSRSDIALIQLKNANNLSEIKIADSDNLRVGDYTVAIGNPYGLGETVTSGIISALGRSGLNIEHYENFIQTDAAINRGNSGGALVNLKGELIGINTAILAPDGGNIGIGFAIPCNMVKNLTAQMVQFGQVRRGELGIMGMELNSDLAQIMKINSQKGAFVSRVLPNSSAFEAGIKAGDIIISLNRKPISSFSSLRAEIGSLPVATKMELGVFREGRIKNITVELKHSVKHNLNSENDYIGIEGVDLSDYIFNEQKVIKVDNVKPHTPASKIGFKKDDIILNVNQKLISNVDELKKFLHSKPKILVFNIKRGNDTIYLVSE
What are the official names of this protein?
Probable serine protease do-like.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1C family.
Protein: ATR13_STAC4
Sequence: MALEEISERLQVSDFPTLGMAANYDLRRHKFESLANDGSHEMRADVRRWVGNPSDFGGCNPINGHIIALTMPMIKPDRVKIAGYIYECWFLYSWDLTTTLTGADGFFHDDILEGTNEGVSDTDAFGLGTADQDAKARDGRKQIQAKMMYLLETTDKACAKHLQKVWSNMLVTTIQHKSRDFETLKEYIDFRIRDCGALFGEGVMLFGMGLALTEKDREDVASTIYPCYAALGLTNDYFSFDREWEEAKRTGEAKFSNAVRLFMDWQSTGAAAAKEVVRKAIIEYEREFLELREKFVKANPKAERLHKFLEAMVYQISGHVVWSINCPRYNPSFRYDPNSGVENQVLAERRGKSSSKKPSVMIEEIDEKSHLASETGPAMIA
What is the function of this protein?
Terpene cyclase; part of the core atranone cluster (CAC) which products are predicted to catalyze most or all steps of mycotoxin atranone synthesis, starting from geranylgeranyl pyrophosphate (GGPP) (PubMed:25015739).  The initial cyclization of GGPP to dolabellane is probably performed by the terpene cyclase ATR13 (PubMed:25015739).  The Baeyer-Villiger oxidation near the end of the atranone synthesis, which converts atranones D and E to atranones F and G is predicted to be catalyzed by the monooxygenase ATR8 (PubMed:25015739).  Of the CAC's other predicted gene products, the reducing PKS ATR6 might synthesize a polyketide chain (PubMed:25015739).  This polyketide is probably transferred onto the atranone backbone by the polyketide transferase ATR5 (By similarity).  Other predicted CAC products include 4 oxygenases (ATR2, ATR3, ATR4, and ATR14), 3 short-chain reductases (ATR7, ATR9, and ATR10), and a methyltransferase (ATR12) (PubMed:25015739).  These may all be involved in the various steps of atranone biosynthesis, although their specific roles must await experimental determination (PubMed:25015739).
What are the official names of this protein?
Terpene cyclase ATR13, Core atranone cluster (CAC) protein 13.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: TRMD_STAA3
Sequence: MKIDYLTLFPEMFDGVLNHSIMKRAQENNKLQINTVNFRDYAINKHNQVDDYPYGGGQGMVLKPEPVFNAMEDLDVTEQTRVILMCPQGEPFSHQKAVELSKADHIVFICGHYEGYDERIRTHLVTDEISMGDYVLTGGELPAMTMTDAIVRLIPGVLGNEQSHQDDSFSDGLLEFPQYTRPREFKGLTVPDVLLSGNHANIDAWRHEQKLIRTYNKRPDLIEKYPLTNADKQILERYKIGLKKG
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_BURMS
Sequence: MIQTESRLEVADNTGAREVMCIKVLGGSKRRYASIGDIIKVSVKEATPRGRVKKGEIYNAVVVRTAKGVRRQDGSLIKFDGNAAVLLNNKLEPIGTRIFGPVTRELRSERFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: HOOK_DROWI
Sequence: MSEAKSEMYYSLLEWFKTLNLSAAHNNAEELADGLALAQALNQFAADFFTDSWLAKIKASAVGSNWRLRMSNLKKVTQSLYDYYSEVMNYTLSDFVRPDLQLIAEKCDQVELERLLQLVLGCAVNCAKKQSYITEIMGLEEELQANIMRALQELESTGLVAGERSPSSSASGGAGSGGAVNSLSRNSLSVKALQEERDAMAQKCFETEKKMLLLLDEKTNLQQELQKIQQEFARLEINTTAIGDDGVSLGPVQAGSVRFNEMRRQLDLLKEELLQSEGAREDLKLKAVQQESDLVHMQQRIDELLKSSAEVTTLKDEVDVLRESNDKLKICEAQLDTYKKKLEDYNDLKKQIKILEERSADYVQQNAQFEDDAKRYANTKGQIELFKKEIQDLHSKLDIESGKNVKLEFDNKNLESKNLALQRAKESLVKERDNLRETVDELKCGHLTNNSGLTGCVEGTTMSRELQPTAMMDKIQRLEAENKALREGQGGQTALAQLLDDANKRCEHLRDQLKSANERILSLSHASQSDDPILKENEFAKQIKQLMELNEQKTLQLEEAVTQNASYQSKVIQLETSLSSREQEILACDAKYRKCVQKAKEIIKNIDPHIANAIDASALEKNMVDVVDEESKPKMSVMEEQLMTTAFYRLGVNAQRDAVDSKLAILMGSGQTFLARQRQSAPRKSLSAMKSK
What is the function of this protein?
Involved in endocytic trafficking by stabilizing organelles of the endocytic pathway.  Probably acts as a cytoskeletal linker protein required to tether endosome vesicles to the cytoskeleton.  Involved in modulation of endocytosis at stages required for down-regulation of membrane proteins that control synapse size.  Not involved in synaptic vesicle recycling.  Required in R7 cells for boss endocytosis into multivesicular bodies (MVBs).  Has a role in regulating adult longevity.
What are the official names of this protein?
Protein hook.
What is the protein family that this protein belongs to?
Belongs to the hook family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Endosome. Synapse. Note=Enriched at neuromuscular synapses, in both presynaptic and postsynaptic regions.
Protein: RL34_COXBU
Sequence: MKRTYQPSKQKRNRTHGFRARMATKNGRQVLNRRRAKGRKRLTV
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: YQGF_STRSY
Sequence: MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIPIDEEKGEFGLERLTELVEQYKVDKFVVGLPKNMNNTSGPRVEASQAYGDLLTERYKLPVDYQDERLTTVAAERMLIEQADISRGKRKKVIDKLAAQLILQNYLDRTF
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQRE_PSEAB
Sequence: MEHYISLFVKAVFVENMALAFFLGMCTFIAISKKVETAIGLGIAVIVVQTITVPANNLIYTYLLKDGALAWAGLPEVDLSFLGLLSYIGVIAAIVQILEMLLDKYVPSLYNALGVFLPLITVNCAIMAGSLFMVERDYNLAESTVYGVGSGFSWALAIAALAGIREKLKYSDVPEGLQGLGITFITIGLMSLGFMSFSGVQL
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit E, Na(+)-NQR subunit E, Na(+)-translocating NQR subunit E, NQR complex subunit E, NQR-1 subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: WEE1_MOUSE
Sequence: MSFLSRQQPPPTRRVGAAYSLRQKLIFSPGSDCEEEEEEEEEGSGHSTGEDSAFQEPDSPLPSARSPAEAEAERRRRSPGAEPSSPGELEDDLLLQGGGGGAQAAGGGAEGDSWEEEGFGSSSPVKSPSTAYFLSSPFSPVRCGGPGDASPQGCGAPRAMDDPCSPQPDYPSTPPHKTFRKLRLFDTPHTPKSLLSKARVIDSGSVKLRGSSLFMDTEKSGKREFDTRQTPQVNINPFTPDPVLLHSSGRCRGRKRAYFNDSSEDMEASDYEFEDETRPAKRITITESNMKSRYTTEFHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQHPHVVRYFSAWAEDDHMLIQNEYCNGGSLADAISENYRVMSYLTEVELKDLLLQVGRGLRYIHSMSLVHMDIKPSNIFISRTSIPNAVSEEGDEDDWISNKVMFKIGDLGHVTRISSPQVEEGDSRFLANEVLQENYSHLPKADIFALALTVVCAAGAEPLPRNGEQWHEIRQGRLPRIPQVLSQEVTELLRVMIHPDPERRPSAMELVKHSVLLSASRKSAEQLRIELNAEKFKNSLLQKELKKAQMAAKVAAEERALFTDRMATRSTTQSNRTSRLIGKKMNRSVSLTIY
What is the function of this protein?
Acts as a negative regulator of entry into mitosis (G2 to M transition) by protecting the nucleus from cytoplasmically activated cyclin B1-complexed CDK1 before the onset of mitosis by mediating phosphorylation of CDK1 on 'Tyr-15'.  Specifically phosphorylates and inactivates cyclin B1-complexed CDK1 reaching a maximum during G2 phase and a minimum as cells enter M phase.  Phosphorylation of cyclin B1-CDK1 occurs exclusively on 'Tyr-15' and phosphorylation of monomeric CDK1 does not occur.  Its activity increases during S and G2 phases and decreases at M phase when it is hyperphosphorylated.  A correlated decrease in protein level occurs at M/G1 phase, probably due to its degradation (By similarity).
What are the official names of this protein?
Wee1-like protein kinase, Wee1A kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPB3_ASFP4
Sequence: MEKIFQNVEIKPFLIDFSNPFIKNAAKRLFQLEEQLPLVPVNVVMDFKGINRAAVHGLSRVLQDEIPNYMLDIKPGGYKIEDSTDLFMTEQFIRNRINFIPIYAKNETLVFALRSLNNSCEVKTIYSRDLIQVAGPKLKYPIFNPTFEIGFLQPGKSLIIEDIYIKRGIGRKHAAFNLAVKTHFSHLDIEQYPTDKKEYMALSGYKQSSMTSDPRHHRLGLCFPAVPLPHINQAVRTYLKNACRVIIGRIQSIQKIYENFEEPQPELVLFSMDEEKTKAIITIKDETHTIGNLLKTYIYEMIPDISFVGYQCVPHKQEMVLTIIHKASQEDLITLLEKSIQNIIQTFQILEKNVDELIA
What is the function of this protein?
Component of the DNA-directed RNA polymerase (RNAP) that catalyzes the transcription in the cytoplasm of viral DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase RPB3-11 homolog, RPB3-11 homolog.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Host cytoplasm. Virion. Note=Found in association with viral nucleoid.
Protein: YCJS_ECOLI
Sequence: MKSAMTSSPLRVAIIGAGQVADKVHASYYCTRNDLELVAVCDSRLSQAQALAEKYGNASVWDDPQAMLLAVKPDVVSVCSPNRFHYEHTLMALEAGCHVMCEKPPAMTPEQAREMCDTARKLGKVLAYDFHHRFALDTQQLREQVTNGVLGEIYVTTARALRRCGVPGWGVFTNKELQGGGPLIDIGIHMLDAAMYVLGFPAVKSVNAHSFQKIGTQKSCGQFGEWDPATYSVEDSLFGTIEFHNGGILWLETSFALNIREQSIMNVSFCGDKAGATLFPAHIYTDNNGELMTLMQREIADDNRHLRSMEAFINHVQGKPVMIADAEQGYIIQQLVAALYQSAETGTRVEL
What is the function of this protein?
Catalyzes the NADH-dependent reduction of the oxo group at C3 of 3-dehydro-D-glucosides leading to D-glucosides.  Probably functions in a metabolic pathway that transforms D-gulosides to D-glucosides.  Can use 3-dehydro-D-glucose, methyl alpha-3-dehydro-D-glucoside and methyl beta-3-dehydro-D-glucoside as substrates in vitro.  However, the actual specific physiological substrates for this metabolic pathway are unknown.  To a lesser extent, is also able to catalyze the reverse reactions, i. e.  the NAD(+)-dependent oxidation of the hydroxyl group at C3 of D-glucosides leading to 3-dehydro-D-glucosides.  Cannot act on UDP-glucose, UDP-N-acetyl-D-glucosamine, D-glucosamine, N-acetyl-D-glucosamine, or UDP-D-galactose.
What are the official names of this protein?
D-glucoside 3-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
Protein: NHRF1_HUMAN
Sequence: MSADAAAGAPLPRLCCLEKGPNGYGFHLHGEKGKLGQYIRLVEPGSPAEKAGLLAGDRLVEVNGENVEKETHQQVVSRIRAALNAVRLLVVDPETDEQLQKLGVQVREELLRAQEAPGQAEPPAAAEVQGAGNENEPREADKSHPEQRELRPRLCTMKKGPSGYGFNLHSDKSKPGQFIRSVDPDSPAEASGLRAQDRIVEVNGVCMEGKQHGDVVSAIRAGGDETKLLVVDRETDEFFKKCRVIPSQEHLNGPLPVPFTNGEIQKENSREALAEAALESPRPALVRSASSDTSEELNSQDSPPKQDSTAPSSTSSSDPILDFNISLAMAKERAHQKRSSKRAPQMDWSKKNELFSNL
What is the function of this protein?
Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.  Necessary for recycling of internalized ADRB2.  Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3.  Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3.  May enhance Wnt signaling.  May participate in HTR4 targeting to microvilli (By similarity).  Involved in the regulation of phosphate reabsorption in the renal proximal tubules.  Involved in sperm capacitation.  May participate in the regulation of the chloride and bicarbonate homeostasis in spermatozoa.
What are the official names of this protein?
Na(+)/H(+) exchange regulatory cofactor NHE-RF1, NHERF-1, Ezrin-radixin-moesin-binding phosphoprotein 50, EBP50, Regulatory cofactor of Na(+)/H(+) exchanger, Sodium-hydrogen exchanger regulatory factor 1, Solute carrier family 9 isoform A3 regulatory factor 1.
What are the subcellular locations of this protein?
Cytoplasm. Apical cell membrane. Endomembrane system; Peripheral membrane protein. Cell projection, filopodium. Cell projection, ruffle. Cell projection, microvillus. Note=Translocates from the cytoplasm to the apical cell membrane in a PODXL-dependent manner. Colocalizes with CFTR at the midpiece of sperm tail (By similarity). Colocalizes with actin in microvilli-rich apical regions of the syncytiotrophoblast. Found in microvilli, ruffling membrane and filopodia of HeLa cells. Present in lipid rafts of T-cells.
Protein: CAMT_PINTA
Sequence: MASTSVAAAEVKAQTTQAEEPVKVVRHQEVGHKSLLQSDALYQYILETSVYPREPEPMKELPRVTAKHPWNLMTTSADEGQFLGLLLKLINAKNTMEIGVYTGYSLLSTALALPDDGKILAMDINRENYDIGLPIIEKAGVAHKIDFREGPALPVLDELLKNEDMHGSFDFVFVDRDKDNYLNYHKRLIDLVKVGGLIAYDNTLWNGSVVAPPDAPLRKYVRYYRDFVMELNKALAVDPRIEISQIPVLDGVTLCRRVY
What is the function of this protein?
Methylates caffeoyl-CoA to feruloyl-CoA and 5-hydroxyferuloyl-CoA to sinapoyl-CoA.  Plays a role in the synthesis of feruloylated polysaccharides.  Involved in the reinforcement of the plant cell wall.  Also involved in the responding to wounding or pathogen challenge by the increased formation of cell wall-bound ferulic acid polymers.
What are the official names of this protein?
Caffeoyl-CoA O-methyltransferase, Trans-caffeoyl-CoA 3-O-methyltransferase, CCoAMT, CCoAOMT.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. CCoAMT subfamily.
Protein: CYSC_GLOC7
Sequence: MKQRGVTIWLTGLSGAGKSTITEALAQKLREQDYPLEVLDGDVVRTNLTKGLGFSKEDRDENIRRIGFVCNLLTRHGVFVLVSAISPYREIREEVRGKIGDFVEVFVNAPLAVCEQRDVKGLYKRARAGEIKSFTGIDDPYEPPLNPEVECRTDLEELDESVNKILHKLDQLGYLR
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Adenylyl-sulfate kinase, APS kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
Protein: SU1_MAIZE
Sequence: MAQQLPCVSSPRPLLAVPAGRWRAGVRGRPNVAGLGRGRLSLHAAAARPVAEAVQAEEDDDDDDEEVAEERFALGGACRVLAGMPAPLGATALRGGVNFAVYSSGASAASLCLFAPGDLKADRVTEEVPLDPLLNRTGNVWHVFIHGDQLHGMLYGYRFDGVFAPERGQYYDVSNVVVDPYAKAVVSRGEYGVPAPGGSCWPQMAGMIPLPYNKFDWQGDLPLGYHQKDLVIYEMHLRGFTKHNSSKTKHPGTYIGAVSKLDHLKELGVNCIELMPCHEFNELEYFSSSSKMNFWGYSTINFFSPMARYSSSGIRDSGCGAINEFKAFVREAHKRGIEVIMDVVFNHTAEGNEKGPILSFRGIDNSTYYMLAPKGEFYNYSGCGNTFNCNHPVVREFIVDCLRYWVTEMHVDGFRFDLASILTRGCSLWDPVNVYGSPMEGDMITTGTPLVAPPLIDMISNDPILGNVKLIAEAWDAGGLYQVGQFPHWNVWSEWNGKYRDTVRQFIKGTDGFAGAFAECLCGSPQLYQAGGRKPWHSINFVCAHDGFTLADLVTYNSKYNLSNGEDNRDGENHNLSWNCGEEGEFASLSVRRLRKRQMRNFFVCLMVSQGVPMFYMGDEYGHTKGGNNNTYCHDHYVNYFRWDKKEEQSSDLYRFCRLMTKFRKECESLGLEDFPTSERLKWHGHQPGKPDWSEASRFVAFTMKDETKGEIYVAFNTSHLPVVVGLPERSGFRWEPVVDTGKEAPYDFLTDGLPDRAVTVYQFSHFLNSNLYPMLSYSSIILVLRPDV
What is the function of this protein?
Isoamylase starch-debranching enzyme involved in amylopectin biosynthesis in endosperm (PubMed:7773016, PubMed:9625695).  Functions by removing excess branches or improper branches that interfere with the formation of double helices of the cluster chains of amylopectin and crystallization of starch (PubMed:9625695).
What are the official names of this protein?
Isoamylase SU1, chloroplastic, Protein SUGARY 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.