PharMolix/UniProtQA huggingface dataset:
Protein: MEND_RHOJR
Sequence: MNPSTAQATAVVDELVRGGVREVVLCPGSRNAPLAFALQAADLEGRLRLHMRIDERTAGFLALGLAVAGKRPVPIVMTSGTAVANLGPAVLEANYARVPLVVLSANRPYEMLGTGANQTIEQLGLFGSQVRATISLGLAEDDAGQNSQWRSAVCRVLAAARGTRSGNAGPVHFDIPLREPLVPDVHAQGPVPQGRPGGAAWTTTQHATLDVPMDLDLTPDTIVISGHGSALRPELAGLPTVAEPTAPLHGIPVHPMALPQLKPRQAVITGRPTLHRSVSKVLADPSVAVYALTTGPRWPDVSGNVLATGTRAVVSGEPDRAWINRCRTLSEHTDKAVRAQLAAHPKATGLHVAAAVMDALTDGDQLLLGASNPVRDAALVSYPAPKIRVLSNRGVAGIDGTVSAAVGAALAYEEGRTVALLGDLTFLHDASGLLIGSGEPRPRDLTIVVANDDGGGIFELLEQGDPQYAGVFERVFGTPHGMDLAALCAAYRVEHHLVGLGELSTRLSAPEAPGDRGIRVLEVTTERSGLRELHAAVRAQL
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: HAT1_GIBZE
Sequence: MEDTTQWLSDASTAIHISLVSPSESGLQHVATFNPRHTYSIFGDDEKIFGYQDLKVNLRYRANDMRPHLNISYSKKSGTINELEPTDVAAILDEGNHLPKIAFAKARDFEESSKQLSDDWTPPGKLHTTFDSPEGQYEIWCGNLADPAVKQLNSRLQIFVPLFIEGGTYIGQDPDEDSAELDLSDADRWTFFSLYQKRKVGDKTAYVFVGYSTIYRFYYFQPPTPPASPQSDEWELPNGNMDLGELPCRTRLSQFIILPPFQGKGNGARLYKTIFEHYHKIPQTYEFTVEDPNEAFDDLRDICDLQFLRKMPEFNNLLVDTNIKIPKKGFLPKLIIGSSLLEEIRLRAKIAPRQFGRVLEMHLMSKLPVSVRPTMAIEDQPAATKADQHEAKVWGLIVKQRLYRHNKEVLSQIEPAERVEKLDDTLHGVGLEYARILAAVDRSDKYEGQTTASSKRKLDADEITEDLSNKKARVEDA
What is the function of this protein?
Catalytic component of the histone acetylase B (HAT-B) complex.  Acetylates Lys-12 of histone H4 which is required for telomeric silencing.  Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG.  Involved in DNA double-strand break repair.
What are the official names of this protein?
Histone acetyltransferase type B catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the HAT1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NFYC_MOUSE
Sequence: MSTEGGFGGTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVKMISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPRDELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQTQSGTGQTMQVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQQLYQIQQVTMPAGQDLAQPMFIQSANQPSDGQTPQVTGD
What is the function of this protein?
Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.  NF-Y can function as both an activator and a repressor, depending on its interacting cofactors.
What are the official names of this protein?
Nuclear transcription factor Y subunit gamma, CAAT box DNA-binding protein subunit C, Nuclear transcription factor Y subunit C, NF-YC.
What is the protein family that this protein belongs to?
Belongs to the NFYC/HAP5 subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: AMT2_ALTAL
Sequence: MLNYKKWTQPPNSLIKSIKASRAAYRRLGNSGLLVSNPILGGMHIGDPRWYDWVLDEKDSIALLKAAYDRGINTWDTANIYSNGESERIMGRALRSHNIPRSKVVIMTKCFRAVTDPDVDGDIGSSTAFFPDLTRQSKDYVNHCGLSRASVFQQVEASLRRLNTDYIDVLHIHRFDHHVPPEETMKALHDLVQMNKVRYLGASSMWAHEFAILQHTAEKNNWTKFVSMQNHYNLLYREEEREMIKYCNLTGVGLIPWGPLAAGKLARPPDGKASTFRAINGGAYKDHNPAESEQIARRVHQIAVSRGVPMSHVALAWLNKRVVSPVIGLSSVERMDEVLDARALELSDEEESRLEDPYKAQPPQGHS
What is the function of this protein?
Aldo-keto reductase; part of the gene clusters that mediate the biosynthesis of AM-toxins, host-selective toxins (HSTs) causing Alternaria blotch on apple, a worldwide distributed disease (PubMed:10875335, PubMed:17990954).  AM-toxins are cyclic depsipeptides containing the 3 residues 2-hydroxy-isovaleric acid (2-HIV), dehydroalanine, L-alanine which are common for all 3 AM-toxins I to III.  The fourth precursor is L-alpha-amino-methoxyphenyl-valeric acid (L-Amv) for AM-toxin I, L-alpha-amino-phenyl-valeric acid (L-Apv) for AM-toxin II, and L-alpha-amino-hydroxyphenyl-valeric acid (L-Ahv) for AM-toxin III (Probable).  AM-toxins have two target sites for affecting susceptible apple cells; they cause invagination of the plasma membrane and electrolyte loss and chloroplast disorganization (PubMed:22846083).  The non-ribosomal peptide synthetase AMT1 contains 4 catalytic modules and is responsible for activation of each residue in AM-toxin (PubMed:10875335).  The aldo-keto reductase AMT2 catalyzes the conversion of 2-keto-isovaleric acid (2-KIV) to 2-hydroxy-isovaleric acid (2-HIV), one of the precursor residues incorporated by AMT1 during AM-toxin biosynthesis, by reduction of its ketone to an alcohol (PubMed:15066029).  The cytochrome P450 monooxygenase AMT3 and the thioesterase AMT4 are also important for AM-toxin production, but their exact function within the AM-toxin biosynthesis are not known yet (PubMed:17990954).  Up to 21 proteins (including AMT1 to AMT4) are predicted to be involved in AM-toxin biosynthesis since their expression ishighly up-regulated in AM-toxin-producing cultures (PubMed:17990954).
What are the official names of this protein?
Aldo-keto reductase AMT2, AM-toxin biosynthesis protein 2.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
Protein: ISPH_CAMJJ
Sequence: MIIELAKNYGFCFGVKRAIKKAEQIKDAATIGPLIHNNEEISRLQKNFNVKTLENIQALSNEKKAIIRTHGITKQDLEELRKKDIEIFDATCPFVTKPQQICEQMSKEGYEVVIFGDENHPEVKGVKSYVSTKAYVVLDKKELQNIKLPNKIAVVSQTTKKPEHFMEIVNFLILKTKEVRVFNTICDATFKNQDAIKELSLKSDVMVVVGGKNSANTKQLFLIAKTNCEDSYLIETEEELKKEWFLDKKHCGISAGASTPDWIIQKVIAKIKNFKIN
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: ATPL_SYNWW
Sequence: MGVALGAGLAVSIAGIGGGIGMGIAGGKAFEAIARQPEVGGDVRTLLFITLAFIETLTIYGLLIAFMLVGKA
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: OST2_SCHPO
Sequence: MSSKSGLFLPLSSVITSYNENTNLSLKTIDAFLGFLVVVGGLQFGYALLVGTYPFNSFLSGFISCVGQFVITVGFRMALTQQELQSSSSKKKSPVVSPYKRAFLEFCFSSLVLHFFAVNFLG
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.
What are the official names of this protein?
Probable dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit ost2, Oligosaccharyl transferase 16 kDa subunit, Oligosaccharyl transferase subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the DAD/OST2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: LCB1C_ORYSJ
Sequence: MMEMVLPVANATAAALARVSAVFNAPLARAVVFGIHIDGHLVVEGLLIAAILFQLSRKSYKPPKKPLTEREVDELCDDWQPEPLCPPIKEGARIDTPTLESAAGPHTTVDGKEVVNFASANYLGLIGNEKIIDSCVGSVEKYGVGSCGPRSFYGTIDVHLDCESKIANFLGTQDSILYSYGISTIFSVIPAFCKKGDIIVADEGVHWAVQNGLQLSRSTVVYFKHNDMASLASILEKLTHGNKHTEKIRRYIVVEAIYQNSGQIAPLDEIVRLKEKYRFRVILEESHSFGVLGKSGRGLAEHYGVPVEKIDIITAGMGNALATDGGFCTGSVRVVDHQRLSSSGYVFSASLPPYLASAAMSAVNHLEENPSVLANLRSNIALLHKELSDIPGLEIASNILSPIVFLKLKTPTGSAVADLELLEIIAEKVLMEDSVFIAATKRSSLDKCRLPVGIRLFVSAGHTESDIFKVSASLKRVAASVV
What is the function of this protein?
Serine palmitoyltransferase (SPT).  The heterodimer formed with LCB2 constitutes the catalytic core (By similarity).
What are the official names of this protein?
Long chain base biosynthesis protein 1c.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: RL2_HAEDU
Sequence: MAIVKCKPTSAGRRHVVKVVNAELHKGKPYAPLLDTKSKTGGRNNLGRITTRHIGGGHKQHYRLIDFKRNKFDIPAVVERLEYDPNRSANIALVLYKDGERRYILAPKGLSVGDMIQAGASAPIKVGNALPMRNIPVGTTVHNVELKPGKGGQIARSAGAYVQIIAREGNYVTLRLRSGEMRKVLAECIATIGEVGNSEHMLRVLGKAGANRWRGIRPTVRGTAMNPVDHPHGGGEGRNFGKHPVTPWGVQTKGKKTRHNKRTDKYIVRRRGK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: ODP2_CORGL
Sequence: MAFSVEMPELGESVTEGTITQWLKSVGDTVEVDEPLLEVSTDKVDTEIPSPVAGVILEIKAEEDDTVDVGGVIAIIGDADETPANEAPADEAPAPAEEEEPVKEEPKKEAAPEAPAATGAATDVEMPELGESVTEGTITQWLKAVGDTVEVDEPLLEVSTDKVDTEIPSPVAGTIVEILADEDDTVDVGAVIARIGDANAAAAPAEEEAAPAEEEEPVKEEPKKEAAPEAPAATGAATDVEMPELGESVTEGTITQWLKAVGDTVEVDEPLLEVSTDKVDTEIPSPVAGTIVEILADEDDTVDVGAVIARIGDANAAAAPAEEEAAPAEEEEPVKEEPKKEEPKKEEPKKEAATTPAAASATVSASGDNVPYVTPLVRKLAEKHGVDLNTVTGTGIGGRIRKQDVLAAANGEAAPAEAAAPVSAWSTKSVDPEKAKLRGTTQKVNRIREITAMKTVEALQISAQLTQLHEVDMTRVAELRKKNKPAFIEKHGVNLTYLPFFVKAVVEALVSHPNVNASFNAKTKEMTYHSSVNLSIAVDTPAGLLTPVIHDAQDLSIPEIAKAIVDLADRSRNNKLKPNDLSGGTFTITNIGSEGALSDTPILVPPQAGILGTGAIVKRPVVITEDGIDSIAIRQMVFLPLTYDHQVVDGADAGRFLTTIKDRLETANFEGDLQL
What is the function of this protein?
Is essential for both 2-oxoglutarate dehydrogenase (ODH) and pyruvate dehydrogenase (PDH) activities, but AceF has exclusively transacetylase (and no transsuccinylase) activity.  The lipoyl residues required for ODH activity are likely provided by AceF.
What are the official names of this protein?
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex, Pyruvate dehydrogenase complex component E2, PDH component E2.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoacid dehydrogenase family.
Protein: RRF_BACCZ
Sequence: MGQQVLKSSNEKMEKAVAAYSRELATVRAGRASASVLDKVQVDYYGAPTPVVQLANITVPEARLLVIQPYDKTSIGDIEKAILKADLGLNPSNDGTVIRIAFPALTEERRRDLVKVVKKYAEEAKVAVRNVRRDGNDDLKKLEKAGEITEDDLRGYTEDIQKETDKYIAKVDEIAKNKEKEIMEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBB1_CARML
Sequence: MKSVKELNKKEMQQINGGAISYGNGVYCNKEKCWVNKAENKQAITGIVIGGWASSLAGMGH
What is the function of this protein?
Has antibacterial activity against Listeria and Enterococcus.
What are the official names of this protein?
Bacteriocin carnobacteriocin BM1, Carnobacteriocin B1.
What is the protein family that this protein belongs to?
Belongs to the bacteriocin class IIA/YGNGV family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS8E_THEAC
Sequence: MTIFQGKSGKKATGGSLKQSRKKRRFELGREPTLTKLGTKTERKVIRTMGGNTKVILFTAETANVYDASEKKIKKAKIITVKANPANSHYVQRNIINKGTVIATEIGDAVVTSRPGQDGVINAKLLK
What are the official names of this protein?
30S ribosomal protein S8e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS8 family.
Protein: GCH1_PYRNV
Sequence: MVLEKRGVVKPEEGVRALLEHLGEDVTRPGVVDTPKRFVKALGELTRGLREPPPEVVFFPLEYDAEPGPVVIENISAVSLCEHHLLPILLSVSVAYIPGDGVPGLSKVIRLVKWAAARPIMQERFTEWLADLLMEKLRARAVAVEVCGVHMCSFIRGVRDEHHNMVTRAKRGDIDVKLRCRRPPLCR
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: MOAA_CLOPS
Sequence: MKDKYGREIDYLRISLTDKCNLRCAYCMEKDHNDFIHNDKLMTLDEILRVVKECASIGIKKVRLTGGEPLVREGIVDLIKNINKIPEIEEICLTTNGILLGDKVKELSENGLKRVNISLDTLKEDRFKEITRIGTLDKVLYSIEKCLENNVKVKINTVILEDFNKDEILDLINLAYKNPIDLRFIELMPIGEGKKFKGVTNSEILEIIKKEKKVLSDGKTLRLNGPAKYISIEGFKGKIGFISAMSDCFCEDCNRIRVTPEGFMKQCLHWKYGINLRDKMRNGISDEELREIIKKSIYEKPEKHNFKMKEKDEDKRFMYEIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: METK2_FRACC
Sequence: MATRLFTSESVTEGHPDKIADQISDSILDAMIKDDPKSRVAVETLITTGQVHVAGEVTTKTYVDIASVVRERILEIGYDSSKKGFDGASCGVSVSIGAQSPDIAQGVDTAHETRVEGSADDEFDRQGAGDQGLMFGFACDETPELMPLPIALAHRLARRLSAVRKEGQIGYLRPDGKTQVTIEYVDGKPARLDTVVVSSQHAADIDLDTLLAPDIAEYVVEPELALLEIATEGRRLLVNPTGRFEIGGPMGDAGLTGRKIIVDTYGGYARHGGGAFSGKDPSKVDRSAAYAMRWVAKNVVAAGLASRCEVQVAYAIGKAQPVGLFVETFGTGTVPDIQIQDAVTSVFDLRPAAIIRDLDLLRPVYAQTAAYGHFGRPELDFTWESTARAEALQRAVKG
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase 2, AdoMet synthase 2, MAT 2, Methionine adenosyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATB1_METHJ
Sequence: MKEYRTITQVAGPLVFVEKTEPVGYQELVNLVLADGSEKRGQVLDTSDDIVVVQVFETTTGIGKDTGVRFTGETIKMPVGKDMLGRILSGAGKPKDGGPDIVPEKRLEITGAAINPWARGSPRQFIQTGISTIDLTNTLVRGQKLPIFSGSGLPHNEIALQIARQAKVPGSDEQFAVVFAAMGITKEEENQFMAEFERTGALEHAVVFLNLADDPAVERIITPRLALTTAEYLAFELDYHVLVILTDMTNYCEALRQIGAAREEVPGRRGYPGYMYTDLASLYERAGIIKGKKGSVTQLSILTMPGDDITHPIPDLSGYITEGQIVVNRDLHRKGIYPPINVLPSLSRLMNLGIGKGFTREDHKKVSDQLYAGYAEGVDLRGLVAIVGKDALSERDRGFLEFAEMFENRFVRQGKDEDRTIDESLDLGWDLLKDIPEEQLVRIDRELIQKYHPKYRKKAE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The archaeal beta chain is a regulatory subunit.
What are the official names of this protein?
V-type ATP synthase beta chain 1, V-ATPase subunit B 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: CCME_NITOC
Sequence: MTVRQRRFAMVILVVIGVSIATGLGLKAFQENILFFYNPTQIMAGEVPTDTSIRVGGVVVNGSVKRESGNLDVQFDLTDMAQTVTVVYSGLLPDLFREGQGIVAMGKLGPNKVFEASEVLAKHDEEYMPPEVADSLAKTKANTEDKL
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: METN_CLOAB
Sequence: MIEIKNVSKYFSGNKVLKDVDLKIKGGEIFGIVGHSGAGKSTLLRCINGLETYDEGNVIVFGKDLKQINGKNLREFRKEVGMIFQNFNLLNRKDVYHNISLPLEVWGVPKNEIASRVKELLELVDLTDKIHSKPSNLSGGQKQRVAIARALALNPKILLCDEATSALDPNTTKSILNLLRTINSKLGITIVIVTHQMEVVKGICERVALIDAGVIKETGDVENLFLNPSSEMKKLIGQSDDDVLPKEGINIRVIFPKNSSEGALITSMARELNVDFSIVWGKLERFRDDVLGSLVINISEENKEVICNYLVSHNAIWEVA
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: YQGE_ECOL6
Sequence: MNLQHHFLIAMPALQDPIFRRSVVYICEHNTNGAMGIIVNKPLENLKIEGILEKLKITPEPRDESIRLDKPVMLGGPLAEDRGFILHTPPSNFASSIRISDNTVMTTSRDVLETLGTDKQPSDVLVALGYASWEKGQLEQEILDNAWLTAPADLNILFKTPIADRWREAAKLIGVDILTMPGVAGHA
What are the official names of this protein?
UPF0301 protein YqgE.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: GVPA2_STRCO
Sequence: MITYDDEVVCAPRAGTLYDVLELILDRGMVIDVFVRVSLVGIEILKVDARIVVASVDTYLRFAEACNRLDLEHDVRSKTVPEMFGSPMAKTVGRAGARRTARSLTDKVRDVLTPEHEHEEEPEEAEDRPRAGAERGRSTQRPRSRPAARPRDEDDRPRSRPRRRTEEEDR
What is the function of this protein?
Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms.  They allow the positioning of the organism at the favorable depth for growth.  GvpA type proteins form the essential core of the structure (By similarity).
What are the official names of this protein?
Probable gas vesicle structural protein 2, GVP.
What is the protein family that this protein belongs to?
Belongs to the gas vesicle protein type A family.
What are the subcellular locations of this protein?
Vacuole, gas vesicle membrane.
Protein: DIAA_SALDC
Sequence: MLERIKVCFTESIQTQIAAAEALPDAISRAAMTLVHSLLNGNKILCCGNGTSAANAQHFAASMINRFETERPSLPAIALNTDNVVLTAIANDRLHDEVYAKQVRALGHAGDVLLAISTRGNSRDIVKAVEAAVTRDMTIVALTGYDGGELAGLLGPQDVEIRIPSHHSARIQEMHMLTVNCLCDLIDNTLFPHQDD
What is the function of this protein?
Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein.
What are the official names of this protein?
DnaA initiator-associating protein DiaA.
What is the protein family that this protein belongs to?
Belongs to the SIS family. DiaA subfamily.
Protein: TFA_BPSF5
Sequence: MSRTLDLILLCRLVQDTAHLLMRITLQWDINEMSYFYSASTNGFYSTEFHGTNIPDDAVEISESEWETLINSQGVTKMITCGENGHPVIVDRPSPTPERLALINDEKKSALIAEATNVIAPLQDAVDLGMATDDETKLLLAWEKYRVLLMRVDIKNTEWPKKPEGNK
What is the function of this protein?
Chaperone involved in tail fiber assembly.
What are the official names of this protein?
Probable tail fiber assembly protein, P37.
What is the protein family that this protein belongs to?
Belongs to the tfa family.
Protein: PANC_BACHK
Sequence: MKIVTTVQEMQHITKELRASGKSIGFVPTMGYLHEGHATLLRKAREENEIVVLSVFVNPLQFGPNEDLDRYPRDIDRDENVAKENGVDYLFYPSVEEMYPAEQTTTVEVVKRTDVLCGKQRPGHFAGVATVLMKLFNITLPTRAYFGMKDAQQVAVIEGFVADFNIPVIIVPVDIVREEDGLAKSSRNVYLSQEERKEAPHLYRSLCMAKERIEAGERNAEIITTLVKEYIETYTKGTVDYADLYAYPSLQVVDQIEGRIILAIAVKFENVRLIDNITLTVK
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPIA_PONPY
Sequence: MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE
What is the function of this protein?
Catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).  Exerts a strong chemotactic effect on leukocytes partly through activation of one of its membrane receptors BSG/CD147, initiating a signaling cascade that culminates in MAPK/ERK activation (By similarity).  Activates endothelial cells (ECs) in a proinflammatory manner by stimulating activation of NF-kappa-B and ERK, JNK and p38 MAP-kinases and by inducing expression of adhesion molecules including SELE and VCAM1 (By similarity).  Induces apoptosis in ECs by promoting the FOXO1-dependent expression of CCL2 and BCL2L11 which are involved in EC chemotaxis and apoptosis (By similarity).  In response to oxidative stress, initiates proapoptotic and antiapoptotic signaling in ECs via activation of NF-kappa-B and AKT1 and up-regulation of antiapoptotic protein BCL2 (By similarity).  Negatively regulates MAP3K5/ASK1 kinase activity, autophosphorylation and oxidative stress-induced apoptosis mediated by MAP3K5/ASK1 (By similarity).  Necessary for the assembly of TARDBP in heterogeneous nuclear ribonucleoprotein (hnRNP) complexes and regulates TARDBP binding to RNA UG repeats and TARDBP-dependent expression of HDAC6, ATG7 and VCP which are involved in clearance of protein aggregates (By similarity).  Plays an important role in platelet activation and aggregation (By similarity).  Regulates calcium mobilization and integrin ITGA2B:ITGB3 bidirectional signaling via increased ROS production as well as by facilitating the interaction between integrin and the cell cytoskeleton (By similarity).  Binds heparan sulfate glycosaminoglycans (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase A, PPIase A, Cyclophilin A, Cyclosporin A-binding protein, Rotamase A.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase A subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Nucleus. Note=Secretion occurs in response to oxidative stress in vascular smooth muscle through a vesicular secretory pathway that involves actin remodeling and myosin II activation, and mediates ERK1/2 activation.
Protein: OPGD_XYLF2
Sequence: MYRRDFLKSVTAAWVAFGLPNPLGGAFATNRVIPLRRLGQSQRFDYEWLKERARALAATPYHSRKRVLPTPLERLSWDQYQSIRYRQDHALWADSDAHFQVKFFHLGLYFHSPVRMYEVVDGMAQELAYDPAAFDYGSSGLNGKGLPKDLGFAGFRLNTRKDIDRDFAAFLGASYFRAVGQEGQYGQSARGLAVNTGSSGPEEFPDFIAYYLEQPTADADTVVMYGLLDSPSIAGAYRFSITHADVLRMDIDSALYPRETIERLGIAPCTSMYQVGENDRRMGWDWRPEIHDTDGLFLWTGNGEWIWRPLCNPLHLRFNMFLDNNPRGFGLLQRDRDFDHYQDDGVFYEKRPCLWVEPKHGWGEGSVQLVEIPTFDETFDNIVAFWNPRNKPHPGQELLFGYRLYWGAFPPVSSSLAYCVATRTGLGGVVGQKRKYFSWRFAVDFVGGKLAALARVHDVSVEPVLHMTRGRPEIVSARPLHEIRGYRVMFDVVPLEDSAQQIDIRLYLRDTNGEPLTETWLYQWVPPILEERKY
What is the function of this protein?
Probably involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis protein D.
What is the protein family that this protein belongs to?
Belongs to the OpgD/OpgG family.
What are the subcellular locations of this protein?
Periplasm.