PharMolix/UniProtQA huggingface dataset:
Protein: LARA_THETC
Sequence: MANIEIPYGKSKLAFDLPDERIQGILRSKAGSYKVNMSEEDIVKRALENPIGTKRLQDLAEGKKNIVIITSDHTRPVPSRITLPLLLDEIRKKNKSANVKILIATGFHRGTTLQEMKAKFGEDLVENEQFVVHDSRNSENMELIGTLPSGGKLEINKLAVEADLLVAEGFIEPHFFAGFSGGRKSILPGIASVQCILANHCSEFIKNPYARTGVLENNPIHRDMIYAAKKANLAFILNVVIDSSHKIVNAFAGHSEKAHLKGCEFVSEIATVNAKPADIVITSNGGYPLDQNIYQSVKGMTAGEAACKDGGVIIIAAECADGHGGEGFYRWFKESKDPQDVMNKILSRGRDETLPDQWEAQILARILINHKVIMVTDSKNYEYVKDMFMTPAKDLGEALKIAESIVNNDSKINVIPDGVSVIVREK
What is the function of this protein?
Catalyzes the interconversion between the D- and L-isomers of lactate.
What are the official names of this protein?
Lactate racemase, Lar.
What is the protein family that this protein belongs to?
Belongs to the lactate racemase family.
Protein: PUR7_BIFLS
Sequence: MEKLEKLYEGKAKQLYATDDPEVLWVEYKNTATAGDGEKKEDFTGKGRLNNLITTIIFDLLKKRGIDSHLIKRVNDTGQLVRKVNMFPLEIVLRNVAAGHFCSRLGVEEGLPLKEPVLEYFLKNDDLHDPFVNDDDLVALDVCTREDLAEIAPLARKINEALIEIFAKIDVKLVDFKIEMGRATDGTLLLADEITPDSCRLWDQKDHSGKVEHLDKDLFRRGLGSIIPAYEEIEERLAELAKSEGIEVAE
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: ECMA_DICDI
Sequence: MKISIFILLLFISSMVIISVNAETETIQTNTACDCDDDCDDGNRWSTDMCSAGLLFGKYCTHTQICCDDENACTIDSCSKTSGCVHTPINVDDKNPCTIDSCIKGFISHTQISCDDKNACTIDSCDCSSGCQNKPMSCDDNNPCTVDSCNNSTGCRNTPISVDDNNPCTIDSCSKSTGVVHIPINVDDLNPCTIDACTKEGGVTHTPVNVDDNNKCTTDSCSLFTGITHTEICCDDNNACTDDSCSPSTGCVNTPISCDDKNPCTVDSCNNSTGCCYTPINVDDNNPCTIDACTKSTGVTHTPINVDDNNQCTTDSCTKEGGVTHTPVNTDDNNPCTVDSCSPFTGVSHTPINVDDNNKCTIDACTKEGGVTHTPVNTDDNNACTLDSCSPLTGVTHTPINCDDKKACTVDSCSNSTGCVNTPISCDDNNPCTVDTCDDSTGCCNTPINVDDNNPCTVDACTKSTGVTHTPVNVDDNNKCTIDACTKEGGVTHTPVNTDDNNACTLDNCSPLTGVTHTPINCDDKKACTVDSCSNSTGCVNTPISCDDNNPCTVDSCDDITGCCNTPINVDDNNPCTVDACTKSTGVTHTPVNVDDNNKCTIDACTKEGGVTHTPVNTDDNNACTLDSCSPSTGVSHTPINCDDSNPCTVDSCSNSTGCVNTPVNVDDNNPCTVDACTKSTGVTHTPVNVDDNNKCTIDACTKEGGVTHTPVNTDDNNACTIDSCSPSTGISHTPINCDDKKACTVDSCSNSTGCVNTPISCDDNNPCTVDSCDDLTGCCNTPINVDDNNPCTIDACTKSTGVTHTPVNVDDNNKCTIDTCTKEGGVTHTPVNTDDNNACTLDSCSPSTGVSHTPINCDDNNKCTVDSCSNSTGCVNTPINCDDSNPCTVDSCNNSTGCVNTPVNVDDNNPCTVDACTKSTGVTHTPVNVDDNNKCTIDACTKEGGVTHTPVNTDDNNACTIDACTKEGGVTHTPVNTDDNNACTLDSCSPSTGVSHTPINCDDSNPCTVDSCSNSTGCCNTPINVDDNNPCTVDSCTKPTGVTHTPVNVDDNNKCTIDACTKEGGVTHTPVNTDDNNACTLDSCSPSTGISHAPINCDDSNPCTIDSCNNSTGCCNTPINVDDNNPCTVDSCTKSGGVTHTPVNVDDNNKCTTDACTKEGGVTHTPISCDDNNACTIDSCSNSTGCVNTPISCDDRNPCTVDTCTKEKGCQHSPIDTDDSNKCTIDACSSTTGVTHTSINCDDNNACTFDSCSNSTGCVSTPISCDDKNPCTLDSCDKKTGCCNTPINVDDNDKCTTDSCTKEGGVTHTPISCDDNNACTTDSCSKSTGCVNKPISCDDSNPCTVDSCSNSTGCCNTPINVDDNNPCTTDSCTKSGGVTHTPVNVDDNNKCTTDSCTKEGGITHTPISCDDNNPCTLDSCSPTTGCVNKPMNVDDNDACTTDTCNKDGTITHTPINTDDNNKCTLDACSPKTGVTHTPINCDDGNKCTINSCSPSVGCISTPVSCPKPKDKCSISQCDSAKGCIEVPMNCTSDKCNEASCCDGVCTSKPISCPKPKNKCQVAKCDLIKGCTVSNVVCDDGNACTEDSCCSDTGKCQFEPIKLPKNKNKCIISKCDPIKGTITNSTVNCECDDLCNIGECCEDTGKCNYRQKDCDDNNPKTADSCDSKTGKCINKPYNVITSGSNLISGLIGGLIGGGTGGKGDCKTCKN
What are the official names of this protein?
Extracellular matrix protein A, Extracellular matrix protein ST430.
What are the subcellular locations of this protein?
Secreted.
Protein: MSHR_ALOPI
Sequence: MPMQGAQRRLLGSLNSTPTATPNLGLAANHTGAPCLEVSIPDGLFLSLGLVSLVENVLVVAAIAKNRNLHSPMYCFICCLALSDLLVSGSNMLEMAVILLLEAGALATRASVVQQLQNTIDVLTCSSMLCSLCFLGAIAVDRYVSIFYALRYHSIVTLPRARRAIAAIWVASVLSSTLFIAYCDHAAVLLCLVVFFLAMLVLMAVLYVHMLARACQHAQGITRLHKRQLPAHQGFGLRGAATLTILLGIFFLCWGPFFLHLMLVVLCPQHLTCSCIFKNFKVFLTLIICNTIIDPLIYAFRSQELCRTLREVLLCSW
What is the function of this protein?
Receptor for MSH (alpha, beta and gamma) and ACTH.  The activity of this receptor is mediated by G proteins which activate adenylate cyclase.  Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes.
What are the official names of this protein?
Melanocyte-stimulating hormone receptor, MSH-R, Melanocortin receptor 1, MC1-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: WECG_ESCF3
Sequence: MNNNTTAPTYTLRGLQLIGWRDMQHALDYLFADGQLKQGTLVAINAEKMLTIEDNAEVRALINAAEFKYADGISVVRSVRKKYPQAQVSRVAGADLWEELMARAGKEGTPVFLVGGKPEVLAQTEAKLRNQWNVNIVGSQDGYFKPEQRQALFERIHASGAQIVTVAMGSPKQEIFMRDCRLVHPDALYMGVGGTYDVFTGHVKRAPKIWQTLGLEWLYRLLSQPSRIKRQLRLLRYLRWHYTGNL
What is the function of this protein?
Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis.
What are the official names of this protein?
UDP-N-acetyl-D-mannosaminuronic acid transferase, UDP-ManNAcA transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 26 family.
Protein: CYC_STELP
Sequence: MGFKEGDAKKGANLFKTRCAQCHTLGEGEGNKIGPNLHGLFGRHTGSVEGFSYTDANKAKGIEWNKDTLFEYLENPKKYIPGTKMAFGGLKKDKDRNDLITFLQDSTK
What is the function of this protein?
Electron carrier protein.  The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase.  Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
What are the official names of this protein?
Cytochrome c.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane.
Protein: TPIS_CLOBK
Sequence: MRTAIIAGNWKMNKTVKEAVELVKELKPLVKDAKCDVVVCPTYVCLPAVLEEVKGSNIKVGAQNMHFEESGAYTGEIAPKMLEELGVHYVIIGHSERRQYFNETDETVNKKVKKAFEHNLIPIVCCGESLEEREGNITEKVLEGQIKVGLKELSKEQVEKLVIAYEPIWAIGTGKTATDEQANETIGYIRTVVKDMYGESVADKVRIQYGGSVKPGTIKAQMAKEEIDGALVGGASLKAKDFAAIVNY
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_SALAI
Sequence: MVMTTAAASSPRTYQVRTYGCQMNVHDSERIAGLLEQAGYLRAGDADDVPDVVVFNTCAVRENADNRLYGNLGQLRPSKDRHPGMQIAVGGCLAQKDRSEIVRRAPWVDVVFGTHNIGSLPVLLERARHNAAAEVEILESLDVFPSTLPTRRESTYAGWVSISVGCNNTCTFCIVPALRGKERDRRPGDVLSEVRALVDEGVLEVTLLGQNVNSYGIEFGDRYAFGKLLRACGDIDGLERVRFTSPHPKDFTDDVIAAMAETPNVCHSLHMPLQSGSDDVLRAMRRSYRSERYLGIIEKVRAAMPDAAITTDIIVGFPGETEADFERTLDVVRSARFSSAFTFQYSKRPGTPAATMADQLPKPVVQERYERLVACVEEITWAENRRLVGETVEVLVAVGEGRKDERTGRLSGRARDGRLVHFDAGSLAGQIRPGDVVHTTVTYAAPHHLNADGEPLAHRRTPAGDAAEAGRRPRTAGVSLGLPTVGAPPSPVPPAASSACAC
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF3_NEIMA
Sequence: MSQEILDQVRRRRTFAIISHPDAGKTTLTEKLLLFSGAIQSAGTVKGKKTGKFATSDWMDIEKQRGISVASSVMQFDYKDHTVNLLDTPGHQDFSEDTYRVLTAVDSALMVIDAAKGVEAQTIKLLNVCRLRNTPIVTFMNKYDREVRDSLELLDEVENILQIRCAPVTWPIGMGKNFKGVYHILNDEIYLFEAGGERLPHEFDIIKGIDNPELEQRFPLEIQQLRDEIELVQAASNEFNLDEFLAGELTPVFFGSAINNFGIQEILNSLIEWAPAPKPRDATVRMVEPDEPKFSGFIFKIQANMDPKHRDRIAFLRVCSGKFERGMKMKHLRINREIAASSVVTFMSHDRELVEEAYAGDIIGIPNHGNIQIGDSFSEGEQLTFTGIPFFAPELFRSVRIKNPLKIKQLQKGLQQLGEEGAVQVFKPMSGADLILGAVGVLQFEVVTSRLANEYGVEAVFDNASIWSARWVSCDDKKKLAEFEKANAGNLAIDAGGNLAYLAPNRVNLGLTQERWPDIVFHETREHSVKL
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GAG2_DROME
Sequence: MSQPIIALSDINLAEARRQLKDIMPFKGDPETLHTFISRVDYVISLYQTNDVRQQRILLGAIERNLDGQITRSLGLPNVEDWPTLKARLIAEFKIQTPNYKLLENFRETPYRGSLRAFCEEAERRRQLLISKLHLEGNQSDFLIYIQGIKESIKILIRKLPIQLFTILAHHDITDLRSLITIAQNEGIYEEHINFEFYEKPEYRNKNSNSNQNSKTQKFNTNVQTQNRPSYSQYSQPFQPNFNQYIQPFRPSYTQQITNNPPMWHAPNYFRPNQYINPQPIIQKNHFQQYPNKAQFPQTTHFRGNTYPRLQQPSTYKNTNFPITKRLRPSDSEQTKMSIDEIRFQDAHEFEQVQPNYYEQQYFNQNQYNPYQNHSFINEGQQQVQFVQINNKQNQNNSELNENFRLTVPENTNT
What are the official names of this protein?
Retrovirus-related Gag polyprotein from transposon 297.
What are the subcellular locations of this protein?
Virion.
Protein: TBCD_HUMAN
Sequence: MALSDEPAAGGPEEEAEDETLAFGAALEAFGESAETRALLGRLREVHGGGAEREVALERFRVIMDKYQEQPHLLDPHLEWMMNLLLDIVQDQTSPASLVHLAFKFLYIITKVRGYKTFLRLFPHEVADVEPVLDLVTIQNPKDHEAWETRYMLLLWLSVTCLIPFDFSRLDGNLLTQPGQARMSIMDRILQIAESYLIVSDKARDAAAVLVSRFITRPDVKQSKMAEFLDWSLCNLARSSFQTMQGVITMDGTLQALAQIFKHGKREDCLPYAATVLRCLDGCRLPESNQTLLRKLGVKLVQRLGLTFLKPKVAAWRYQRGCRSLAANLQLLTQGQSEQKPLILTEDDDEDDDVPEGVERVIEQLLVGLKDKDTVVRWSAAKGIGRMAGRLPRALADDVVGSVLDCFSFQETDKAWHGGCLALAELGRRGLLLPSRLVDVVAVILKALTYDEKRGACSVGTNVRDAACYVCWAFARAYEPQELKPFVTAISSALVIAAVFDRDINCRRAASAAFQENVGRQGTFPHGIDILTTADYFAVGNRSNCFLVISVFIAGFPEYTQPMIDHLVTMKISHWDGVIRELAARALHNLAQQAPEFSATQVFPRLLSMTLSPDLHMRHGSILACAEVAYALYKLAAQENRPVTDHLDEQAVQGLKQIHQQLYDRQLYRGLGGQLMRQAVCVLIEKLSLSKMPFRGDTVIDGWQWLINDTLRHLHLISSHSRQQMKDAAVSALAALCSEYYMKEPGEADPAIQEELITQYLAELRNPEEMTRCGFSLALGALPGFLLKGRLQQVLTGLRAVTHTSPEDVSFAESRRDGLKAIARICQTVGVKAGAPDEAVCGENVSQIYCALLGCMDDYTTDSRGDVGTWVRKAAMTSLMDLTLLLARSQPELIEAHTCERIMCCVAQQASEKIDRFRAHAASVFLTLLHFDSPPIPHVPHRGELEKLFPRSDVASVNWSAPSQAFPRITQLLGLPTYRYHVLLGLVVSLGGLTESTIRHSTQSLFEYMKGIQSDPQALGSFSGTLLQIFEDNLLNERVSVPLLKTLDHVLTHGCFDIFTTEEDHPFAVKLLALCKKEIKNSKDIQKLLSGIAVFCEMVQFPGDVRRQALLQLCLLLCHRFPLIRKTTASQVYETLLTYSDVVGADVLDEVVTVLSDTAWDAELAVVREQRNRLCDLLGVPRPQLVPQPGAC
What is the function of this protein?
Tubulin-folding protein implicated in the first step of the tubulin folding pathway and required for tubulin complex assembly.  Involved in the regulation of microtubule polymerization or depolymerization, it modulates microtubule dynamics by capturing GTP-bound beta-tubulin (TUBB).  Its ability to interact with beta tubulin is regulated via its interaction with ARL2.  Acts as a GTPase-activating protein (GAP) for ARL2.  Induces microtubule disruption in absence of ARL2.  Increases degradation of beta tubulin, when overexpressed in polarized cells.  Promotes epithelial cell detachment, a process antagonized by ARL2.  Induces tight adherens and tight junctions disassembly at the lateral cell membrane (PubMed:10722852, PubMed:10831612, PubMed:11847227, PubMed:20740604, PubMed:27666370, PubMed:28158450).  Required for correct assembly and maintenance of the mitotic spindle, and proper progression of mitosis (PubMed:27666370).  Involved in neuron morphogenesis (PubMed:27666374).
What are the official names of this protein?
Tubulin-specific chaperone D, Beta-tubulin cofactor D, tfcD, SSD-1, Tubulin-folding cofactor D.
What is the protein family that this protein belongs to?
Belongs to the TBCD family.
What are the subcellular locations of this protein?
Cell junction, tight junction. Lateral cell membrane. Cytoplasm. Cell junction, adherens junction. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localized in cell-cell contacts.
Protein: Y2368_DEIRA
Sequence: MNDTLLTTYTLAEGLHWLDLIGVLAFAMSGALLGVRKRFDLFGVLVLGAVTAVGGGAIRDSLTGQTPPLFLRDETYLWTALLGALLAFAFGERLARFERTLSLFDSAGLALFATSGALGAIKIGLGPLGVVFAGMLSGVGGGIIRDLIANEVPEVMYRRDQLYATAAAAGAGAVWLLAPHFTPFQAQAGGALLVLFLRWVSRRQWVRLPVRRLPE
What are the official names of this protein?
UPF0126 membrane protein DR_2368.
What is the protein family that this protein belongs to?
Belongs to the UPF0126 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MATK_ANNMU
Sequence: MEELQRYFEIDRFRQQCFIYPFLFQEYIYALAHYYALNGSIFYETMENFGYDNKSSSLIVKRLITRMHRQNRLIISINDSNQNRFIGHGKNLYTQTVSEGFAVIMEIPFSLQLVFSFEEKEITKSHNLRSIHSIFPFFEDKLSHLNHVSHILIPYPAHLEILVQILRSCIQDAPSLHLLRFFLHDYQNSNSLKARKKSIFVCSKENRRFFLFLYNIHVYECESVFVFLRKQSFHLRSTSFRTVLERTHFYGKIEHLVVVLRNDFQKTLWMFKDPFMHYVRYQGNSLLASKGTHLRMKKWKSYLVHFWQSHFYLWSQPNRIHINQLYNHSFYFMSYLLSVRQNSSAVRSQMLENSFLIDTSIKKFETLVPTIPLIGLLAKAKFCNVFGHPISKPARADSSDSDIISRFGRIYRNLSHYYSGSSKKQTLYRIKYILRLSCARTLARKHKSTARAFLKELGSPFLEEFLMEEEQVLSLIFPRTPSPSYRSHRERIWFLDIICINILTNHV
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CCG6_RAT
Sequence: MMWSNFFMQEEDRRRTAVGRRRAQEQQNLGLTPEREGKIKLGLLVAIVGATLAVLAVGTEFWVELNTYKTNGSAVCEAAHLGLWKVCIKRLWQADVPAGRETCGPAELPGEANCTYFKFFTTGENAHIFQRTTKKEVNLAAAVIAVLGLTAMALGCLCVIMVLSKGAEFLLRLGAVCFGLSGLLLFVSLEVFRHSVRALLQGVNPETPPAPRLAYEYSWSLGCGVGAGLILLLGGVCFLLLTLPSWPWRSLCPKRGGPTA
What is the function of this protein?
Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit.
What are the official names of this protein?
Voltage-dependent calcium channel gamma-6 subunit, Neuronal voltage-gated calcium channel gamma-6 subunit.
What is the protein family that this protein belongs to?
Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATPA_ORITB
Sequence: MQLKASEVYEALKQQLEDFDELSELSEVGYVISIGDGIAKVYGLSNAYSGEILQFSTGTKGIVFSLKDNLIEVVVIGSGDQIKQGSQVKRTQTSLKVPTGKELLGRVVDAIGNPIDGKGEFINPTYLDVEVKAPSVMCRDSVNEPMYTGIKAIDALIPIGKGQRELIIGDRQTGKTAIAIDIILNQKRFHLSDQEKEKVYCIYVAIGQKRSTVAQLVKKLQETGAMAYTTVVLSSASDAASLQYLAPYTGCAIGEYFRDNCMHALVIYDDLSKHAIAYRQISLLLRRPPAREAYPGDVFYLHSRLLERAAKLNKAKGEGSLTALPIVETQNSDVSAYIPTNIISITDGQIFLESELFYKGIKPALNVGISVSRVGAAAQIKAMKDIASSVKLELAQYHEMEAFSQFGADLDSSSMQLINRGRRLSELLKQSQYCPFPVEEQIIVLFAGINGYLDKIAVSKVKEFENNMLEYFRIHNPDIMNEIINTKKITEIISSKLHQILQEFVKSIEQCS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y161B_ATV
Sequence: MTLYDTVKELQEKLRNGEIEINTFLERLGLTLDSIWSQKLRVTGLFKYNVIKATLLSIAKTTCMYYFNKIPDVEAEDSIITTLTKIYSFISQNVKENRDKFETELVAFGKQNEIKSVADSIMIMIVENLMASLGYTETEKKYIPISDFMIRLQNIQNTTGS
What are the official names of this protein?
Uncharacterized protein ORF161b.
Protein: ERA_GEODF
Sequence: MTEQQFHSGFVSIIGRPNVGKSTLLNKILGDKIVITSDKPQTTRNRIQGIHNLPGCQIVFIDTPGIHRAKSRLNKYMVDVALSSIKEVDVILFLVEADTKPANQEETILGALASAEAPVVLVINKVDLVAKESLLEKMAAYSGLYPFREVIPVSALTGDNTGRLVQVVRDLLPEGPPYFPDDILTDVPERFVVAEIVREKVFRLTHDEVPYSVAVVVESFKERDDGLILISAVINVERDSQKGIIIGRKGEMLKKIGMQARREIEELLDTRIFLELFVRVSREWSENKQMLKEFGYE
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: RSGA_YERE8
Sequence: MSKNKLSKGQQRRVQANHQRRLRTDRKPELDDSQLGDAQEGIVISRFGQHADVEAADGVQHRCNIRRTIKSLVTGDRVVWRPGLQAQEGVRVKGIVEAVHERTSVLTRPDLYDGVKPIAANIDQIVIVSAILPELSLNIIDRYLVACETLDVEPLIVLNKIDLLDADGRKFVDGMMDIYRRIGYNVLEVSSQTREGMEAFEQALAGRISIFAGQSGVGKSSLLNALLPPTDNEILVNTVSDNSGLGQHTTTAARLYHFQHGGDVIDSPGVREFGLWHLAPEQITQGFVEFRDYLGHCKFRDCSHTNDPGCALREAVEQGKIAEERFDNYHRILESMEQAKPRKTSDSDEK
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPE_AERS4
Sequence: MSDVIALAKDLIRRPSVTPQDEGCQTLMSERLARLGFVIEPMVFEDTTNLWARRGSEGPLFCFAGHTDVVPAGPLEKWHTPPFEPTIQDGVLYGRGAADMKGSLAAMVVAVERFVAEHPDHKGSIAFLITSDEEGPFINGTVRVIDTLEARNEKIRWCIVGEPSSTHVVGDVVKNGRRGSITGDLLVRGVQGHVAYPHLADNPIHKAAPALTELAATVWDEGNAYFPPTSFQIANIQAGTGASNVIPGELQVQFNFRFSTQLTDMDIRERVQALLDKHGLDYELTWTLSGQPFLTDTGALLEATVAAVAAVNGQQPALLTTGGTSDGRFIAPTGAEVIELGPVNATIHKVNECVKAEDLDLLAEMYQGVLERLLA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: UVRB_KLEP7
Sequence: MSKSFVLHSAFRPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKALLERRDVVVVASVSAIYGLGDPDLYLKMMLHLTVGMLIDQRAILRRLAELQYTRNDQAFQRGTFRVRGEVIDVFPAESDDIALRIELFDEEVERLSLFDPLTGHVEGTVPRYTIYPKTHYVTPRERIVQAMEEIKLELAERRKVLLANNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGEPPPTLFDYLPADGLLVIDESHVTVPQIGGMYRGDRARKETLVEYGFRLPSALDNRPMKFEEFEALAPQTIYVSATPGAYELDKSGGEVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRLRTAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDIDTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPSMAKAIGETERRREKQQRYNEEHGIVPQGLNKKVVDILQLGQGLAKTKAKGRGKAKAVEPAGLSAVDMTPKALQQKIHELEGQMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIO_OPHHA
Sequence: MVKIVGDLTEFRAELSNAGSKLIVVDFSATWCGPCKMIKPFFHSMVEKYPDVVFIEIDVDDAQDVASHCDVKCMPTFQFYKNNEKVHEFSGANKEKLEEAIKKYM
What is the function of this protein?
Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (By similarity).  Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide.  Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity.  Induces the FOS/JUN AP-1 DNA binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity (By similarity).
What are the official names of this protein?
Thioredoxin, Trx.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Secreted. Note=Shuttles between the nucleus and nucleolus.
Protein: RLF19_ARATH
Sequence: MGIKILLILGLLTLAVVAESANATWTLTKSCVNGQGCIGEDGELDYLMDSETNRRQLAARRSYISYGALRKNNVPCSRRGRSYYDCKKRKRANPYRRGCSVITHCYRQTS
What is the function of this protein?
Cell signaling peptide that may regulate plant stress, growth, and development.  Mediates a rapid alkalinization of extracellular space by mediating a transient increase in the cytoplasmic Ca(2+) concentration leading to a calcium-dependent signaling events through a cell surface receptor and a concomitant activation of some intracellular mitogen-activated protein kinases (By similarity).
What are the official names of this protein?
Protein RALF-like 19.
What is the protein family that this protein belongs to?
Belongs to the plant rapid alkalinization factor (RALF) family.
What are the subcellular locations of this protein?
Secreted.
Protein: CAPSD_HASV3
Sequence: MASKSDKQVTVEVKNNNNGRNRSRSRARSQSRGRGKSVKITVNSRSRGRRQNGRDKYQSNQRVRNIVTKQLRKQGVTGPKPAICQRATATLGTIGSNTSGTTEIEACILLNPVLVKDATGSTQFGPVQALGAQYSMWKLKYLNVKLTSMVGASAVNGTVVRVSLNPTSTPSSTSWSGLGARKHLDVTVGKNAVFKLKPADLGGPRDGWWLTNTNDNASDTLGPSVEIHTLGMTMSSYKNEQFTGGLFLVELASEWCFTGYAANPNLVNLEKSTDKQVNVTFEGSNGTPLIMKVPEASHFARTAVARSSLPTTLARAGQNTTSDTVWQVLNTAVSAAELVTPPPFNWLVKGGWWFVKLIAGRARTGTRSFYVYPSYQDALSNKPALCTGSAPSGMRSRAAVMTTLQFTQMNQPSLGHGEMTATLGRAIPSPGDTFNVVLTIGQPLAPNTLTKQSWLNKTTVSPQNHHVVKIAKDVNNYTTMQGFTPISSVDWYTTDFQPSEEPTPIPGLQVLVNSSKKADVYAIQQYLNNQTNNKVQLTSIFLVKVTTSFQVNNYLSYFYRSYGTGTTVENLKVRSDTTAQDVNFPVGWYLMTNTAIFNAPAPPGWIWQNVELLNDTAYLIDQGMMHLIMPPPANTQLLFEMRTSVTGSRSMISSEEPDTHEPGDEWCDALDASDSRVFLEETDYEDEEDEDEDDEADRFDLHSSYGSEPEDDDENNRVTLLSTLINQGMTVERATRITKRAFPTSADKTKRSVYMDLLASGLSPGNAWSHACEEARIMGTNQMPNVSGDRGHAE
What is the function of this protein?
The capsid polyprotein VP90 self-assembles and undergoes a proteolytic cleavage by host caspases to yield the VP70 virions.  This immature virion is composed of 180 VP70 subunits with 90 dimeric spikes and displays a T=3 icosahedral symmetry.  The mature virion is obtained by further cleavages resulting in three structural proteins VP25, VP27 and VP34.  This forms contains only 30 spikes located on the icosahedral 2-fold axes.  Plays a role in the attachment to target host cell.  This attachment induces virion internalization through clathrin-dependent endocytosis (By similarity).
What are the official names of this protein?
Capsid polyprotein VP90.
What is the protein family that this protein belongs to?
Belongs to the astroviridae capsid polyprotein family.
What are the subcellular locations of this protein?
Virion.