PharMolix/UniProtQA huggingface dataset:
Protein: HTPX_HELAH
Sequence: MNFEKIIAQNKLKTNAVLTTYCVIFAFIGLLVDVIRINANDLGIALFKLITFQIFPTITVIMFLVAFVVIVVCIQNFSSIMLSGDEYKLIDPSKVLSSKENQIHGLLLELLEEAKLNFEPKLYIINAPYMNAFASGWNETNSLIALTSALIERLDRDELKAVIAHELSHIRHNDIRLTMCVGILSNIMLLVANFSVYFFMGNRKNSGANLAKMILLVLQIVLPFLTLILQMYLSRTREYMADSGAAFLMHDSKPMIRALQKISNDYKENDYKEIDTNSTRSAAYLFNAEMFSTHPSIKNRIQSLSRRAL
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FEOC_YERPE
Sequence: MASLLQLRDAIALNGSAEASQLSRQLAIPLPLVNAMLEKLTAMGKIERIELDHSGCLTGSCKSCPEGHQHCNTVIYQLKEPHAHQ
What is the function of this protein?
May function as a transcriptional regulator that controls feoABC expression.
What are the official names of this protein?
Probable [Fe-S]-dependent transcriptional repressor.
What is the protein family that this protein belongs to?
Belongs to the FeoC family.
Protein: PEPB_YERPG
Sequence: MTTEIMQISLSHNPADARWGEKALISTNDQGVTIHLTSHDQLGGIQRAARKIDGQGIKQVKLAGEGWGLEQSWAFWQGFRGPKGQRSVVWAELPANEKTELEQRLKIIDWVRDTINAPAEDLGPEQLAKNAIDLLCAVSCDAVSYRITKGEDLREQNYAGIYTVGRGSDRAPVLLALDYNPTGNPDAPVMACLVGKGITFDSGGYSLKQSAFMDSMKSDMGGAATLTGALALAAARGLKERVKLYLCCADNMVSGNAFKLGDIIRYRNGKTVEIMNTDAEGRLVLADGLIDASEQNAPLIIDAATLTGAAKTALGNDYHALFSFDDELAQALLNSAHSEHELFWRLPLAEFHRSQLPSNFAELNNVAGGAYSAGASTAAAFLSHFVKNYQQGWLHIDCSATYRKSAVDQWSAGATGLGVRTVANLLLAQAKQ
What is the function of this protein?
Probably plays an important role in intracellular peptide degradation.
What are the official names of this protein?
Peptidase B, Aminopeptidase B.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX2_CANSI
Sequence: MAYPFQLGLQDATSPIMEELLHFHDHTLMIVFLISSLILYIISLMLTTKLTHTSTMDAQEVETVWTILPAIILILIALPSLRILYMMDEINNPSLTVKTMGHQWYWSYEYTDYEDLNFDSYMIPTQELKPGELRLLEVDNRVVLPMEMTIRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQTTLMATRPGLYYGQCSEICGSNHSFMPIVLEMVPLSYFETWSALMV
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ATG17_ASHGO
Sequence: MSSSNQVKGFYFNAQRRLSRAQALCQNSQDTLHNMQLLLVRWQRTVSKLQFTIHCICNQTVFLAECILKKTVGQQLIETEWKRMLLDELQGEMQRSQEEITGKIDALRRTKNELDGSGATLADFISMENIFLLGDKLKDVPVVQEQVEHIKVQYESLVDKVVEQLQNNRVRKLEADFAAAFRSGKNDFNAFSMKYLQKIRQLETDLADILKSLTDHYDKCSLLKAGDLPAAEQAELFEVVKNDDQELDSIMGVLEVIVRDIKSLAKNVSIRLRQKERDKQQLKNAMGKAHSELLKYEEHLTVFQGIDDLIRNFKASCLHNVSKVRELCEFYDNFLNSYQVLLREVERRRRVAKQMEDILQACEGQLMALSDTDLKQRQQFLMRHGDYLPENIWPGNIDDLSPLYDLEYRIKKV
What is the function of this protein?
Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation.  Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles.  Plays particularly a role in pexophagy and nucleophagy (By similarity).
What are the official names of this protein?
Autophagy-related protein 17.
What is the protein family that this protein belongs to?
Belongs to the ATG17 family.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: RL17_STRS7
Sequence: MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTVEKMITLGKRGDLHARRQAAAYVRNEIASESYDEATDKYTSTTALQKLFSEIAPRYAERNGGYTRILKTEPRRGDAAPMAIIELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: DEF_CHRSD
Sequence: MAKLTILEFPDERLRTKAAPVETVDDETRKLVDDMLETMYDAQGIGLAATQVDVHRRVIVMDVSDDRSQPRVLINPEYTPLGDEREPMQEGCLSIPEYYAEVPRALRVSLKALDRDGNPYELEADGLLAHCIQHEYDHLEGVLFVDYLSPLKRDRVLKKMQKRHRAMQDA
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: RS4_FLAJ1
Sequence: MARYTGPKTKIARKFGEAIFGDDKSFEKRNYPPGQHGMAKKRGKKSEYAVQLMEKQKAKYSYGILEKQFRNLFEKASATKGVTGEVLLQLCEARLDNVVFRMGIAPSRRGARQIVSHRHITVNGEVVNIPSYHLKPGDKVAVREKSKSLEAIERSLSNSSHVYEWITWNNDLKEGTFVSVPARLQIPENIKEQLIVELYNK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: UNG_MYCPA
Sequence: MTARPLNELVEPGWARALQPVAEQVARMGQFLRAEIAAGRRYLPAGPNVLRAFTYPFDEVKVLIVGQDPYPTPGHAVGLSFSVAPDVSPLPRSLANIFQEYTADLGHPPPSCGDLTPWAQRGVLLLNRVLTVRPSNPASHRGKGWEPVTECAIRALTARQQPLVAILWGRDASTLKPILAQGNCVAIESPHPSPLSASRGFFGSRPFSRANKLLAEMGADEIDWRLP
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LDHA_RAT
Sequence: MAALKDQLIVNLLKEEQVPQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLKTPKIVSSKDYSVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPQCKLLIVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDSSVPVWSGVNVAGVSLKSLNPQLGTDADKEQWKDVHKQVVDSAYEVIKLKGYTSWAIGLSVADLAESIMKNLRRVHPISTMIKGLYGIKEDVFLSVPCILGQNGISDVVKVTLTPDEEARLKKSADTLWGIQKELQF
What is the function of this protein?
Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+).
What are the official names of this protein?
L-lactate dehydrogenase A chain, LDH-A, LDH muscle subunit, LDH-M.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PP71_HCMVM
Sequence: MSQASSSPGEGPSSEAAAISEAEAASGSFGRLHCQVLRLITNVEGGSLEAGRLRLLDLRTNIEVSRPSVLCCFQENKSPHDTVDLTDLNIKGRCVVGEQDRLLVDLNNFGPRRLTPGSENNTVSVLAFALPLDRVPVSGLHLFQSQRRGGEENRPRMEARAIIRRTAHHWAVRLTVTPNWRRRTDSSLEAGQIFVSQFAFRAGAIPLTLVDALEQLACSDPNTYIHKTETDERGQWIMLFLHHDSPHPPTSVFLHFSVYTHRAEVVARHNPYPHLRRLPDNGFQLLIPKSFTLTRIHPEYIVQIQNAFETNQTHDTIFFPENIPGVSIEAGPLPDRVRITLRVTLTGDQAVHLEHRQPLGRIHFFRRGFWTLTPGKPDKIKRPQVQLRAGLFPRSNVMRGAVSEFLPQSPGLPPTEEEEEEEEEDDEDDLSSTPTPTPLSEAMFAGFEEASGDEDSDTQAGLSRALILTGQRRRSGNNGALTLVIPSWHVFASLDDLVPLTVSVQHAALRPTSYLRSDMDGDVRTAADISSTLRSVPAPRPSPISTASTSSTPRSRPRI
What is the function of this protein?
Stimulates viral immediate-early (IE) transcription.  Plays a role in the inhibition of the host innate repsonse by targeting STING1 and thus the cGAS-STING pathway.  Counteracts also host DAXX-mediated repression of viral transcription.  Displaces a DAXX-binding protein, ATRX, from nuclear domain 10 sites (ND10) shortly after infection.  Increases the basal level of SUMOylated DAXX in infected cells.  Stimulates quiescent cells to re-enter the cell cycle, proceed through G1 and enter the S phase.  Interacts with hypophosphorylated forms of RB1 and induces their degradation by the proteasome without involving ubiquitin conjugation.
What are the official names of this protein?
Protein pp71.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae pp71 family.
What are the subcellular locations of this protein?
Virion tegument. Host nucleus. Host endoplasmic reticulum. Note=Present in the nucleus shortly after infection as well as during the late phase of viral morphogenesis. Detected at nuclear domain 10 (ND10).
Protein: GLYA_BORA1
Sequence: MFDRKLTLDKVDPDLWAAIQKEDERQEQHIELIASENYASPAVMQAQGTQLTNKYAEGYPGKRYYGGCEYVDIVEQLAIDRLKELFGAEAANVQPNSGSQANQGVYMAVLKPGDTVLGMSLAEGGHLTHGASVNASGKLYNFLSYGLDENEVLNYAQVEALAREHKPKLIVAGASAYALHIDFERMARIARENGALFMVDIAHYAGLVAGGQYPNPVPHADFVTSTTHKSLRGPRGGVIMMKAQHEKAVNSAIFPGIQGGPLEHVIAAKAVAFKEALSPEFKDYASQVVKNAKVLAETLVKRGLRIVSGRTESHVMLVDLRAKGITGKEAEAVLGKAHITVNKNAIPNDPEKPFVTSGIRLGTPAMTTRGFKEAEAELTGNLIADVLENPHDEANIAAVRAKVNELTSRLPVYSAK
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_SALPA
Sequence: MHCPFCFAVDTKVIDSRLVGEGSSVRRRRQCLVCNERFTTFEVAELVMPRVIKSNDVREPFNEDKLRSGMLRALEKRPVSADDVEMALNHIKSQLRATGEREVPSKMIGNLVMEQLKKLDKVAYIRFASVYRSFEDIKDFGEEIARLQD
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: GPX2_MACFU
Sequence: MAFIAKSFYDLSAISLDGEKVDFNTFRGRAVLIENVASLUGTTTRDFTQLNELQCRFPRRLVVLGFPCNQFGHQENCQNEEILNSLKYVRPGGGYQPTFTLVQKCEVNGQNEHPVFAYLKDKLPYPHDDPFSLMTDPKLIIWSPVRRSDVAWNFEKFLIGPEVEPFRRYSRTFPTINIEPDIKRLLKVAI
What is the function of this protein?
Could play a major role in protecting mammals from the toxicity of ingested organic hydroperoxides.  Tert-butyl hydroperoxide, cumene hydroperoxide and linoleic acid hydroperoxide but not phosphatidycholine hydroperoxide, can act as acceptors.
What are the official names of this protein?
Glutathione peroxidase 2, GPx-2, GSHPx-2, Glutathione peroxidase-gastrointestinal, GPx-GI, GSHPx-GI.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: ACYP_MYXXD
Sequence: MGQSMSGTRRASLRIEGKVQGVFFRESARVEATRLGLTGWVRNRPDGAVEAVVEGEPAVLEEFIHWCHRGPAQARVSGVQRTDSKATGEFSQFNVERTS
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: 3SX6_OXYMI
Sequence: MKTLLLSLVVMTIVYLDLGYTLKCHESENLDDHVVCEEDETMCYKFTFVPFRDFEIVARGCSASCPEEKDVVCCSTDLCNK
What are the official names of this protein?
Three-finger toxin 3FTx-Oxy6.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MACD_PENTR
Sequence: MVNIIQPKVDPLPTGIGLTGKTVVITGASAGMGLEATKQLLRLRASTVILAVRNVAKGEACATSLRQDRRIQTHNPKPTIKVMELDVDDYHSVQRFSKQLREEIPVVHILILNAGIGLLKLERSASGHDRTTQVNYYSNVLLIAELLPYLQAGAEKTGSPARISWVGSRAHEVTSLEKKAPIKPGEGVLAHMDKEEAFVPFQRYGDSKLLCVMFMYNLAPRLDPKKVIINMMCPGMVNTNMSDVLPMHLRLIVNVVKSFRARPVEVGGWIILNSALVVGPESHGKFLNDKTISDKSAFIKSPAGQEIQKKLWEETINEIGTLTTLPAELK
What is the function of this protein?
Short chain dehydrogenase; part of the gene cluster that mediates the biosynthesis of macrophorins, isoprenoid epoxycyclohexenones containing cyclized drimane moieties (PubMed:28926261).  The first step of the pathway is the synthesis of 6-methylsalicylic acid (6-MSA) by the polyketide synthase macA (PubMed:28926261).  6-MSA is then converted to m-cresol by the decarboxylase macB (By similarity).  The cytochrome P450 monooxygenase macC then catalyzes the oxidation of m-cresol to toluquinol (By similarity).  Epoxidation of toluquinol is then performed by the short chain dehydrogenase macD, with the help of macE, and a further prenylation by macG leads to 7-deacetoxyyanuthone A (By similarity).  The next step is the hydroxylation of C-22 of 7-deacetoxyyanuthone A by the cytochrome P450 monooxygenase macH to yield 22-deacetylyanuthone A (By similarity).  O-Mevalon transferase macI then attaches mevalon to the hydroxyl group of 22-deacetylyanuthone A to produce yanuthone E (By similarity).  The terpene cyclase macJ catalyzes the cyclization of 22-deacetylyanuthone A to macrophorin A (PubMed:28926261).  MacJ is also able to catalyze cyclization of yanuthone E and 7-deacetoxyyanuthone A to their corresponding macrophorins (PubMed:28926261).  The macJ products can be further modified by macH and macJ, as well as by the FAD-dependent monooxygenase macF, to produce additional macrophorins, including 4'-oxomacrophorin A, 4'-oxomacrophorin D and 4'-oxomacrophorin E (PubMed:28926261).
What are the official names of this protein?
Short chain dehydrogenase macD, Macrophorins biosynthesis cluster protein D.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: Y1960_ACIBY
Sequence: MHCDIYRSSKKDEMYIYIARPNYPDETEQADPFEKVPEAVLQAFGRATFVMHLELAPTRKLARVNVLHVLDSLQTKGFFIQMPPEGLINPNAVEPEGLRGA
What are the official names of this protein?
YcgL domain-containing protein ABAYE1960.
Protein: CLUA1_DANRE
Sequence: MSFRDLRNFTEMMRALGYPRLISMENFRSPNFPLVAEILIWLVKRYEPQMEIPSDVDTESDRVFFIKAVAQFMATKAHVKLNLKRLYQADGYAVKEMLKITSILYNAMKTKENAGGDQNNDENSKFKFDLGSKIADLKLARQLGSEITAKGAALFDLLGQEEDLRESRTAAIARPLEITETERAMRAAVKDVTESIQMTKDLLNNVSSDEASLEAKIEKKKQDLERNQKRLQTLQSVRPAFMDEYEKIEEDLEKQYQTYVEKYRNLSFLEQQLDDYHRVEQERFEEAEMAMKMRQNKLKEEEKRLMRSGVARDEDSDVDIPEDEGSDSDIDDGQQARPHHPRHTQISGRGGARFIGSMRGGDSEETEDSEIDVDDDDEDDDEDGEEDEEENEDLDEDNDSLEGSSGKPGRTNQSLHPQILEESDNDF
What is the function of this protein?
Required for cilia biogenesis and maintenance in the kidney, the lateral line organ and eye.  Appears to function within the multiple intraflagellar transport complex B (IFT-B).
What are the official names of this protein?
Clusterin-associated protein 1 homolog, Qilin.
What is the protein family that this protein belongs to?
Belongs to the CLUAP1 family.
What are the subcellular locations of this protein?
Nucleus. Cell projection, cilium.
Protein: CTEN1_CUPSA
Sequence: MKHLIPLIVMASVVLAVYADRGYGGGRRGGGYGGGGYGGGGYGGGGGGYGGGVGGGRGGGGGLGGGRGGGGGVIDGKDDVGLGGGGYGGGLGGGQGGGGGLGGGQGGGGGLGGGRGGGGYGGGGGGYGGGKYGGGKYGGK
What is the function of this protein?
Antimicrobial protein with bacteriostatic activity against the Gram-negative bacterium E. coli, and very weak activity against the Gram-positive bacterium S. aureus.  Lacks activity against the yeast C. albicans.
What are the official names of this protein?
Ctenidin-1, Ctenidin-2.
What are the subcellular locations of this protein?
Secreted.
Protein: IQD21_ARATH
Sequence: MGKKGSGGWFSTVKKKVFKSSPKDSKRENNIGSNNADIWQQQHDTQEVVSFEHFPAESSPEISHDVESTASTPATNVGDRKHAMAVAIATAAAAEAAVAAAQAAAKVVRLAGYNRQTEEDSAAVLIQSHYRGYLARRALRALKGLVRLQALVRGNHVRKQAQMTMKCMQALVRVQGRVRARRLQVAHDRFKKQFEEEEKRSGMEKPNKGFANLKTEREKPKKLHEVNRTSLYQTQGKEKERSEGMMKRERALAYAYTYQRQMQHTNSEEGIGLSSNGPDRNQWAWNWLDHWMSSQPYTGRQTGPGPGPGQYNPPPYPPFPTAAATTTSDDVSEKTVEMDVTTPTSLKGNIIGLIDREYIDLGSYRQGHKQRKSPTHIPSYMAPTASAKAKVRDQGPTVKLQGTSFMPYWNSSTKNGSVNGSGCDSSSSGGAITTGYPGPRSPNPKSDIRRKPVSPSQSPTGFGKRGWRHDH
What is the function of this protein?
May be involved in cooperative interactions with calmodulins or calmodulin-like proteins (By similarity).  Recruits calmodulin proteins to microtubules, thus being a potential scaffold in cellular signaling and trafficking (By similarity).  Involved in abscisic acid (ABA)-mediated signaling pathways leading to the production of hydrogen peroxide H(2)O(2) and the subsequent [Ca(2+)] cytoplasmic oscillations-dependent regulation of stomatal closure (PubMed:10963598, PubMed:11429606).  Required for [CO(2)] modulation of the cytosolic Ca(2+) transient rate and for high CO(2)-induced stomatal closing (PubMed:16651523, PubMed:19302418).  Essential for both cold and ABA induction of XERO2 (PubMed:18088305).  May associate with nucleic acids and regulate gene expression at the transcriptional or post-transcriptional level (By similarity).
What are the official names of this protein?
Protein IQ-DOMAIN 21, AtIQD21, Protein GROWTH CONTROLLED BY ABSCISIC ACID 2, Protein GUARD CELL ASSOCIATED 2.
What is the protein family that this protein belongs to?
Belongs to the IQD family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton. Cell membrane.
Protein: CRCB1_LACAC
Sequence: MSTKTGNYISIAIFAFFGGIARAWLNSSFGFYGTFWGNIIGCFLLAFFTYLFMEFKDVRQWLTVGLGTGFVGAFTTFSTFNLDVLKNIQANVPITALIYFLSSIIFGFCFAYLGMNAGKQVGNLLRKED
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 1.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: COAX_STRGG
Sequence: MLLTIDVGNTHTVLGLFDGEEIVEHWRISTDARRTADELAVLLQGLMGMHPLLGMELGDGIEGIAICATVPSVLHELREVTRRYYGDVPAVLVEPGVKTGVPILMDNPKEVGADRIINAVAAVELYGGPAIVVDFGTATTFDAVSPRGEYTGGVIAPGIEISVEALGVKGAQLRKIELARPRSVIGKNTVEAMQSGIVYGFAGQVDGVVARMKKELAADPDDVTVIATGGLAPMVLGESSVIDEHEPWLTLIGLRLVYERNVSRA
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRE_STAAS
Sequence: MAKEIAKSLLDIEAVTLSPNDLYTWSSGIKSPIYCDNRVTLGYPLVRGAIRDGLINLIKEHFPEVEVISGTATAGIPHAAFIAEKLKLPMNYVRSSNKSHGKQNQIEGAKSEGKKVVVIEDLISTGGSSVTAVEALKLAGAEVLGVVAIFTYGLKKADDTFSNIQLPFYTLSDYSELIEVAENEGKISSEDIQTLVEWRDNLA
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: KATG_RHOCA
Sequence: MDGKDKATGKCPVMHGAMTAAGVSNTSWWPNALNLDILHQHDTKGNPLNGFDYRAAVKGLDVGLRADLHALMTDSQPWWPADWGHYGGLMIRMAWHAAGSYRAADGRGGGNTGKPARFAPLNSWPDNVSLDKARRLLWPIKKKYGNAVSWADLILFAGTVAYESMGLKTFGFGFGREDIWAPEKDVYWGAEKDWLAPSDGRYGDLAKPETMENPLAAVQMGLIYVNPEGVNGQPDPARTALHIRETFARMGMNDEETVALTAGGHTVGKAHGNGDAKALGPDPEAADVTVRALAGRTRIWAARRRRPSPRGSRAPGPRIRRAGTWAISRCSSGHDWELTKSPAGAWQWKPVTIAEEAKPLDATDLTTRHDPLMTDADMAMKVDPSTMRSVRSSWPIRPPSTTLSRAPGSSCCIATWGRRRATSAPMCPPRIWSAGPGAAGPTGWDVAKVKAQIAASGLSVADLVATAWDSARTFRQSDYRGGANGARIRLAPQKDWAGNEPERLAGACGARTDRGGAGASVADVIVLAGNLGVEQAAAGVSRWRCPSPPVAAMRAAMTDGPSLTCWSRCMTASATG
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.  Also displays NADH oxidase, INH lyase and isonicotinoyl-NAD synthase activities.  Important for stationary phase survival.
What are the official names of this protein?
Catalase-peroxidase, CP, Hydroperoxidase I, HPI, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: CSD2_MYCLE
Sequence: MTISLTPLDLSAIRADFPILKRVMRGGNQLAYLDSGATSQRPVQVLDAEREFLVTSNGAVHRGAHQLMEEATDAYERGRVDIAAFIGAAADELVFTKNATESLNLVSYVFGDNRFEGTSGDGGDVIVTTELEHHANLIPWQELARRIGATLRWYGVTDDGQIDLDSLQLDERVKVVAFSHHSNVTGAVAPVRELVARAKEVGALTVLDACQSVPHQPVDLHGLGVDFAAFSGHKMLGPNGIGVLYARRELLSVMPPFLTGGSMIETVTMESTTYAPAPQRFEAGTPMTSQVVGLAAAARYLDAIGMKAVEAHERELVAAAVEGLSRIDGVRIIGPKSMENRGSPVSFVVDGVHAHDIGQVLDDDGVAVRVGHHCALPLHRRFALAATARASFAVYNTVDEVDRLVAGVLRALDFFGRE
What is the function of this protein?
Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
What are the official names of this protein?
Probable cysteine desulfurase 2.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
Protein: LLDD_ECOL6
Sequence: MIISAASDYRAAAQRILPPFLFHYMDGGAYSEYTLRRNVEDLSEVALRQRILKNMSDLSLETTLFNEKLSMPVALGPVGLCGMYARRGEVQAAKAADAHGIPFTLSTVSVCPIEEVAPAIKRPMWFQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPTPGARYRDAHSGMSGPNAAMRRYLQAVTHPQWAWDVGLNGRPHDLGNISAYLGKPTGLEDYIGWLGNNFDPSISWKDLEWIRDFWDGPMVIKGILDPEDARDAVRFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGDIAILADSGIRNGLDVVRMIALGADTVLLGRAFLYALATAGQAGVANLLNLIEKEMKVAMTLTGAKSISEITQDSLVQGLGKELPAALAPMAKGNAA
What is the function of this protein?
Catalyzes the conversion of L-lactate to pyruvate.  Is coupled to the respiratory chain.
What are the official names of this protein?
L-lactate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GPH_VIBCH
Sequence: MKSIKLIAFDLDGTLLDSVPDLAVAADQAARAVGYPAVSEAQVRDYVGNGADVLIARALSQSLTINPELSPELRAQARHLFDEFYEQTGHKLSHLYPNVKTTLLELHQAGFILALVTNKPSKFVPDVLEQHGIAHFFSDVIGGDTFPNKKPDPMALNWLLEKHQLSAEQMLMVGDSKNDILAAKNAGCYSFGLTYGYNHGEPIANAEPDFVSDDIGTLLEVVLVSA
What is the function of this protein?
Specifically catalyzes the dephosphorylation of 2-phosphoglycolate.  Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.
What are the official names of this protein?
Phosphoglycolate phosphatase, PGP, PGPase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.