PharMolix/UniProtQA huggingface dataset:
Protein: GSTUQ_ARATH
Sequence: MANDQVILLDYWPSMFGMRTKMALAEKGVKYEYKETDPWVKTPLLIEMNPIHKKIPVLIHNGKPICESLIQLEYIDEVWSDASPILPSDPYQKSRARFWAEFIDKKFYDPSWKVWATMGEEHAAVKKELLEHFKTLETELGDKPYYGGEVFGYLDIALMGYYSWFKAMEKFGEFSIETEFPILTTWTKRCLERESVVKALADSDRIIEYVYVLRKKFGAA
What is the function of this protein?
In vitro, possesses glutathione S-transferase activity toward 1-chloro-2,4-dinitrobenzene (CDNB).  May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.
What are the official names of this protein?
Glutathione S-transferase U26, AtGSTU26, GST class-tau member 26.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Tau family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: FUSED_DROME
Sequence: MNRYAVSSLVGQGSFGCVYKATRKDDSKVVAIKVISKRGRATKELKNLRRECDIQARLKHPHVIEMIESFESKTDLFVVTEFALMDLHRYLSYNGAMGEEPARRVTGHLVSALYYLHSNRILHRDLKPQNVLLDKNMHAKLCDFGLARNMTLGTHVLTSIKGTPLYMAPELLAEQPYDHHADMWSLGCIAYESMAGQPPFCASSILHLVKMIKHEDVKWPSTLTSECRSFLQGLLEKDPGLRISWTQLLCHPFVEGRIFIAETQAEAAKESPFTNPEAKVKSSKQSDPEVGDLDEALAALDFGESRQENLTTSRDSINAIAPSDVEHLETDVEDNMQRVVVPFADLSYRDLSGVRAMPMVHQPVINSHTCFVSGNSNMILNHMNDNFDFQASLRGGGVAAKPIVAPTVRQSRSKDLEKRKLSQNLDNFSVRLGHSVDHEAQRKATEIATQEKHNQENKPPAEAISYANSQPPQQQPQQLKHSMHSTNEEKLSSDNTPPCLLPGWDSCDESQSPPIENDEWLAFLNRSVQELLDGELDSLKQHNLVSIIVAPLRNSKAIPRVLKSVAQLLSLPFVLVDPVLIVDLELIRNVYVDVKLVPNLMYACKLLLSHKQLSDSAASAPLTTGSLSRTLRSIPELTVEELETACSLYELVCHLVHLQQQFLTQFCDAVAILAASDLFLNFLTHDFRQSDSDAASVRLAGCMLALMGCVLRELPENAELVERIVFNPRLNFVSLLQSRHHLLRQRSCQLLRLLARFSLRGVQRIWNGELRFALQQLSEHHSYPALRGEAAQTLDEISHFTFFVT
What is the function of this protein?
Probable serine/threonine-protein kinase; maternally required for correct patterning in the posterior part of each embryonic metamere.  May be involved in control of cell division during metamorphosis and ovarian development.  May interact with costal-2.
What are the official names of this protein?
Serine/threonine-protein kinase fused.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: NUOH1_SYNFM
Sequence: MGHEGGTEWVRLIVGLVIILAFSQLNALFLVWLERKVAGRIQLRPGPMEVGPHGLLQTIMDGIKLVGKELITPRSVDRKLFILAPVLVFMPVLVGFLVLPFGPGLILRDMNVGILLIFSFSTFTVLAILAGGWASNNKYALLGAIRSVGQNVAYEIPLLLTVMSVVLMVNSMRFSEIVAAQGRVWFIFLQPVAGLLYLICATAETNRAPFDIPEAESELVAGFHTEYTGMRFGLFFLAEYTNMFIVTAVATSLFFGGWHGPFGFDFGLPGVVWFLIKTYVLIFVIMWVRWTFPRIRFDQLMNFSWKFLIPVSLVNLVVTAVVLKLIDLN
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H 1, NADH dehydrogenase I subunit H 1, NDH-1 subunit H 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SECA1_NITHX
Sequence: MIGALARKFFGSANDRRVKGYQARVKAINGLEPEIAALSDEALRARTAEFRQQLADGKTLDDILVPAFATVREAGKRTLGQRHFDVQLIGGMVLHEGDIAEMKTGEGKTLVATLAVYLNALAGKGVHVVTVNDYLASRDAGWMAQIYTFLGLTTGVIVHGLDDVERKAAYACDITYGTNNEYGFDYLRDNMKYRLEDMVQREHFYAIVDEVDSILIDEARTPLIISGPLDDRSEFYNTIDTFMPNLEKVADYEVDEKQRTVALTEAGMEKIETLLRDAGQLKGDSLYDVENVSVVHHINQALRAHSLFTRDKDYIVRDDEVVIIDEFTGRMMQGRRYSEGLHQALEAKEHVTVQPENQTLASITFQNYFRMYKKLSGMTGTALTEADELADIYKLEVVEIPTNLPIARLDEDDEVYRTQNEKYAAILAEVERANARMQPVLVGTASIEKSEVLADYLKKNGYKLIDFGDPKSMRKLYAAARAGKPAKLFAVLNARFHEQEAYIVAEAGVPGAITIATNMAGRGTDIKLGGSLEMRAQFETADLADEAEKDAKIAEIKADIERFRDMVLKAEDVVEIEPAKGSKPAKTVTRPGGLYIIGSERHESRRIDNQLRGRSGRQGDPGRSKFFLSLEDDLMRIFGSDRLDTMLQRLGLKDGEAITHPWINKALEKAQQKVEARNFDIRKNLLKYDDVQNDQRKVIFDQRVDLMMNESVAETVADMRHAFVDDLVTKHVPENQYAEQWDVAGLKEELRRVLDIDLPVDEWAAEEGIADEELLSRIENRVDEHMAAKVGQWGPDVMRYVEKTILLQTLDHLWREHLVMLDHLRQVIGLRGYGQRDPLQEYKSEAFSLFEALIAHLREAVTGQLMRVEIVPPEEEQPVLPAMEVHKLDPHTGEDEMAFAQGNFAQASLAPVVSADRSSRDPGNPASWGKVGRNEDCPCGSGKKYKHCHGR
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 1.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: NURA_PYRFU
Sequence: MRLLSKQSIERITKILLDELENVRENEQIRNIINSWKPLPSPEKSSIYAVDGSRSVSRLSGTVIYFLSALAVGSGKQLRLSYANAIKSNYGTSDQIVRMQMETLENMLGYLAYRKLEGEKRAILMDGTLTGSLVRPPVYPEDIRSLNVMRALIGESDFENLLNEFLEKLRDHYRKVEEHLEKNGNYDSPILTDNVVEKLRKKYIDTKVIAYGSGKVKVKIPRKALGYSPRVIPIEVLESSRGKSVDELLQELDEEKVELYLGKDDIYDALHMTLSYIEYLYSIDKLLEVKNLAYIAKSFYTKTLARTLGVEIVDTALLDAVIRTLIGHEKEGYLEIEHAVVPPKWSFPDFLLSKFRNIEKLIDKGIHLAYVRFEQGDVIYMLQSTTNIEKILPLILHHKAGGYLRPLQLAHHGVKISYKEARHTLEALINALRNRDPALKIFVKYGRSPLE
What is the function of this protein?
Involved in DNA double-strand break (DSB) repair (PubMed:18957200).  Acts probably with HerA to stimulate resection of the 5' strand and produce the long 3' single-strand that is required for RadA loading (PubMed:18957200).  Exhibits 5' endonuclease activity and both 5' and 3' exonuclease activities (PubMed:22064858).
What are the official names of this protein?
DNA double-strand break repair nuclease NurA.
What is the protein family that this protein belongs to?
Belongs to the NurA family.
Protein: VKT1_CRYNI
Sequence: MSSGGLLLLLGLLTLWEALTPVSSTDRPEFCELPEDSGPCKGLFHVFYYNSDQNQCLEFIYGGCYGNANNFKTIEECKRTCAA
What is the function of this protein?
Serine protease inhibitor.
What are the official names of this protein?
Kunitz-type serine protease inhibitor nigrescinin-1.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: DAPA_ALKOO
Sequence: MFKGAGVAIVTPFKEGKIDFAAFEKLIDFHLENNTQALIVLGTTGEASTQTMEEREALIRLAVQRVEGRIPVIVGTGSNCTDTALQYTRQAEDLGADGILVVTPYYNKCTQKGLIEHFTQIANATKLPVILYNVPSRTGVNILPETVATMSKVENVIGIKEAGGNTAQVLEIKRLVPEDFKIYSGNDDQIIPIYACGGHGVISVASNVIPKEIQEMCAAFMEGNVEKALEIQLLYKKFIDLLFCEVNPIPVKAAVSALGYIENELRLPLTPMEEVNRKKLMDEMKKQNII
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNFB_KLEP3
Sequence: MSAVWIAVIAISLLGLIFGLILGYASRRFAVQDDPVVEKIDELLPQSQCGQCGYPGCRPYAEAVGAQGEKINRCAPGGEAVMLKIAALLNVDPQPVDGDEQEAEPVRMLAVIDEPNCIGCTKCIQACPVDAIVGATRAMHTVMNDLCTGCNLCVAPCPTQCISLVPVATTPETWKWDLHAIPVRNIPVEQHV
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit B, Rnf electron transport complex subunit B.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: TUSA_SALTI
Sequence: MSDLFSSPDHTLDALGLRCPEPVMMVRKTVRNMQTGETLLIIADDPATTRDIPGFCTFMEHDLLAQETEGLPYRYLLRKAH
What is the function of this protein?
Sulfur carrier protein involved in sulfur trafficking in the cell.  Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA.  Interacts with IscS and stimulates its cysteine desulfurase activity.  Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation.  Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.
What are the official names of this protein?
Sulfur carrier protein TusA, Sulfur mediator TusA, Sulfur transfer protein TusA, tRNA 2-thiouridine synthesizing protein A.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAA_STRU0
Sequence: MTEISMLKDVQKIIVLDYGSQYNQLIARRIREFGVFSELKSHKITAQEIREINPIGIVLSGGPNSVYADNAFGIDPEIFELGIPILGICYGMQLITDQLGGKVVPAGQAGNREYGQSTLNIRTASKLFADTPDEQLVLMSHGDAVTEIPDGFHLVGDSNDCPYAAIENSEKHIYGIQFHPEVRHSVYGNDILRNFAIFICGARGDWSMDNFIDMQIEKIRETVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHGLLRKDEGDQVMGMLGGKFGLNIIRVDAKDRFLELLAGVDDPEKKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDIIESGTETAQTIKSHHNVGGLPEDMQFQLIEPLNTLFKDEVRELGIALGMPENIVWRQPFPGPGLAIRVMGAITEEKLETVRESDAILREEIAKAGLDRDVWQYFTVNTGVRSVGVMGDGRTYDYTIAIRAITSIDGMTADFAQLPWDVLKKISTRIVNEVDHVNRIVYDITSKPPATVEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: RIMP_BEII9
Sequence: MDLDGKVQPPSAQVGQQPLSPDAALHEPRLLQESGIAARVAVLAAPVLADLGLRLVRVKISGQNGTTVQIMAERPDGTMDVEACESVSEALSPVLDVEDPVKQAYHLEISSPGIDRPLVRLSDFERALGQEVRVELKTGLAGRKRFRGTIGPIEASSPIGGSKGALRLTRTDAKPEEETEVLLPLDDLHEARLVLTEDLIRQALRAAKAAREGDDGNNEEQDEEQEEPAPPRRGPGRFAPRHKTQNPEHNPAQNPISARAKPLVPAGVRTEFKKSKTGERGPAQKPHLASQAARKSDTGSSRSGHDMPRKPAPK
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG23_VANPO
Sequence: MKNQINKLDDILLQQQHTNDYLLELVKFHNNLLHDNLTSIENLNLTRKKILDCFNDLFNLNSIIINYHGDIKLEIKNLKEIIIKFNKLNKLEIFYQNKLNQWKSSKVKQIQSASSTNNKITINCNYQPLLKTYLNQIDPDESTLSNQFNSNLSINDEKLIYTNESFTEDEDDTGDEDNDIDHSNNHTNNDEDPFLILSNIKLLENCQSTIKADINQLEFLLSNYKKDLKFIENELNSQNLKTKYNITLMQEKLDKINIKRKKLLIKIGLSKNKNLTSVLDKDEKIIIENINDFINSKINSLNDQLSNKKENSIVLNQKINLWEQVINQLNDLENSLKIYLSKNKKKKSIDYNIMIEWINDTINNLNDIIDSTDIQLLRNLIENEKKVLVQATNELKLNLTPVNSKINDSISKSINNNNNTNITTNTSINNNNNTNENSLLDSSQFQSSKNPFPNIGTSPPKISISEHIASNNSFTTFQLNNTSNDKLMKNE
What is the function of this protein?
Required for cytoplasm to vacuole transport (Cvt) vesicle formation and efficient autophagy.  Plays a role in ATG protein retrieval from the pre-autophagosomal structure (PAS) and is especially required for autophagy-dependent cycling of ATG9.  Also plays a role in regulation of filamentous growth (By similarity).
What are the official names of this protein?
Autophagy-related protein 23.
What is the protein family that this protein belongs to?
Belongs to the ATG23 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: PG139_VARV
Sequence: MIGILLLIGICVAVTVAILYAMYNKIKNSQNPSPNVNLPPPETRNTRFVNNLEKDHISSLYNLVKSSV
What is the function of this protein?
Essential for the encapsidation of DNA into immature virions (IV) and the subsequent maturation of IV into mature virions (MV).
What are the official names of this protein?
Virion membrane protein OPG139.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG139 family.
Protein: UPP_BORPD
Sequence: MPVHEIRHPLIRHKLGIMRRADLSTKSFRELSQEVGALLTYEASKDLPLAESTVEGWCGTVTVEKIAGKKVTVVPILRAGIGMLDGVLSLIPGAKVSVVGVARNEETLQAHTYLERLVGELDQRLALIVDPMLATGGSMLATIDMLKRAGCREIRALVLVAAPVGIKAVLDRHPDVHIYTASIDDGLNENGYIMPGLGDAGDRIFGTKQKAE
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: DAAF5_XENLA
Sequence: MAAEGEQRATSDVTKALARHLNCLNDENKMIRRRALAAIQKEAADEKLASAVLQHVFLELLKPLLRCLSDPMEKCRELSIQIIVYCVSHVPRPEEALPYLMPALTQRLGQQQLVELSEELRLAMVELLTLLVEVCGKKLAPYLDEMIQIFQRTMVDPFPDVKKESCKCASNYATCIPEHFHMQAESLIKPLMQTISHQHSKVRVAVIQTTGTVIQYSSGKSVDDVLSHLAQRLFDDSVQVRQAVTVVVGDWLLKLQDRYSFFHKLIPLLLSSTTDEIPEIRKLALDYWEKIGSQWEKENEEDLKDKLDFSAPCPSYYPAGVQRPGLGCRELIFRNLSKILPAISRDVTNWVAGTRIKSSQLLAVLLLHGEDHITQHMELLLSTLYHSCLDEENQVVINSVKSAELIGTFVNPEVFLKLILSALQKSPLASHLMTLAACIRGCSREMLKTHLTKITSVISQSDVCQGSERVLYQEQLLCCIQSLIDVCQQDCTEVSLQCMNVLITILASPASESLHKKVQDTLLSLSEVQGLNGPHDLYRQHMQQLLDWVSQSHNHWTSYSVEQRQFEVIATESGPVMGETLHLFVPILKMCLQPTREPQMRLKLFTMLSKLLLKASETVNSQGQLHRYSESFINDMIVPNLKWQAGRTAGAIRTVAVSCLWVLLQSETLSQQEILQVEDNLMPRVITTLEEDSKMCRLMSCCIITALLSTCERQLRPDKLNKIYPELLKRLDDASDEVRVAAAKTLYQWFKCITDEYERTTYKGHLEFLYRGLLVHLDDPDASLQLIVLDLLKEGSAVCPSLLVQEIEAVRHKHRSPAYCDQLLHYIQKYTSPTPTECT
What is the function of this protein?
Cytoplasmic protein involved in the delivery of the dynein machinery to the motile cilium.  It is required for the assembly of the axonemal dynein inner and outer arms, two structures attached to the peripheral outer doublet A microtubule of the axoneme, that play a crucial role in cilium motility.
What are the official names of this protein?
Dynein axonemal assembly factor 5, HEAT repeat-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the DNAAF5 family.
What are the subcellular locations of this protein?
Cytoplasm. Dynein axonemal particle. Note=Observed only in the cytoplasm of ciliated cells and absent from cilia.
Protein: SCP51_ARATH
Sequence: MKTTVVYLVILCLIVSCTNGETKHVRKINSDGSEAWGYVEVRPKAHMFWWHYKSPYRVENPSKPWPIILWLQGGPGASGVGIGNFQEVGPLDTFLKPRNSTWLKKADLLFVDSPVGAGYSFVEGNQKDLYVKSDEEAAQDLTKLLQQLFNKNQTLNQSPLFIVAESYGGKIAVKLGLSVIDAVQSGKLKLHLGGVILGDSWISPEDFVFSWGPLLKHVSRLDDNGLDSSNSLAEKIKTQIKNGEYVGATQTWMDLENLISSKSNFVDFYNFLLDTGMDPVSLTTSLKIKKEEKIKKYSRYLNDMRSLSDVEDVEGDLDKLMNGVIKKKLKIIPNDLIWGNNSDDVFTAMEAAFMKPVIEDVDELLATGVDVTIYNGQLDVICSTSGTEAWVHKLRWEGLEEFKKMEREPLFCESDRATRGFTKSYKNLHFYWILGAGHFVPVDEPCVALKMVGEITKSPQL
What is the function of this protein?
Probable carboxypeptidase.
What are the official names of this protein?
Serine carboxypeptidase-like 51.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PRR2_TOBAC
Sequence: MNFLKSFPFYAFLCFGQYFVAVTHAATFDIVNQCTYTVWAAASPGGGRQLNSGQSWSINVNPGTVQARIWGRTNCNFDGSGRGNCETGDCNGMLECQGYGKPPNTLAEFALNQPNQDFVDISLVDGFNIPMEFSPTNGGCRNLRCTAPINEQCPAQLKTQGGCNNPCTVIKTNEFCCTNGPGSCGPTDLSRFFKARCPDAYSYPQDDPPSLFTCPPGTNYRVVFCP
What are the official names of this protein?
Pathogenesis-related protein R minor form, PR-R, PROB12, Thaumatin-like protein E2.
What is the protein family that this protein belongs to?
Belongs to the thaumatin family.
What are the subcellular locations of this protein?
Vacuole.
Protein: EFG_BRUA2
Sequence: MAREYKIEDYRNFGIMAHIDAGKTTMTERILFYTGKNHKIGETHDGASTMDWMEQEQERGITITSAATTTFWQGRDGKKRRFNIIDTPGHVDFTIEVERSLRVLDGAIALLDANAGVEPQTETVWRQAEKYHVPRMVFVNKMDKIGADFYRSVEMVGSRLGAVALPVQLPIGAENDFVGVVDLIEMKALTWDGTIGAPATVGEIPADMADKAEEYREKLIELAVEIDEAAMEAYLEGTMPTNDELRALIRKGTIEVKFHPILCGTAFKNRGVQPLLDAVVEFLPAPTDVPAIKGIDVKTETETTRESSDEAPLSMLAFKIMNDPFVGSLTFARIYSGKLTKGVSLENTVKGKRERIGRMLQMHSNSREDIDEAFAGDIVALAGLKETTTGDTLCDPLKPVILERMEFPDPVIEIAIEPKTKADQEKMGIALNRLAAEDPSFRVKSDEESGQTIIAGMGELHLDILVDRMKREFKVEANVGAPQVAYRESITRAAEIDYTHKKQSGGSGQFARVKIIFEPHDGDDFIFESKIVGGSVPKEYIPGVQKGIESVMGAGPLAGFPMLGVKATLIDGAYHDVDSSVLAFEIASRAAFREGAQKAGAQLLEPIMKVEVVTPEDYVGDVIGDLNSRRGQISGTEARGIAAVVNAMVPLANMFGYVNSLRSMSQGRAQYTMQFDHYEPVPTAVAQEIQKKFA
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPGS_MYCBO
Sequence: MTASELVAGDLAGGRAPGALPLDTTWHRPGWTIGELEAAKAGRTISVVLPALNEEATIESVIDSISPLVDGLVDELIVLDSGSTDDTEIRAIASGARVVSREQALPEVPVRPGKGEALWRSLAATSGDIVVFIDSDLINPHPLFVPWLVGPLLTGEGIQLVKSFYRRPLQVSDVTSGVCATGGGRVTELVARPLLAALRPELGCVLQPLSGEYAASRELLTSLPFAPGYGVEIGLLIDTFDRLGLDAIAQVNLGVRAHRNRPLDELGAMSRQVIATLLSRCGIPDSGVGLTQFLPGGPDDSDYTRHTWPVSLVDRPPMKVMRPR
What is the function of this protein?
Involved in the biosynthesis of 6-O-methylglucose lipopolysaccarides (MGLPs).  Catalyzes the transfer of the glucose moiety from a nuleotide sugar such as UDP-alpha-D-glucose to the position 2 of 3-phospho-D-glycerate (3-PGA) to form glucosyl-3-phosphoglycerate (GPG).  It can use UDP-glucose, ADP-glucose and GDP-glucose as sugar donor substrates with decreasing affinity and with 3-PGA as an acceptor.  D-glycerate can only be an acceptor with ADP-glucose and at a very low rate.
What are the official names of this protein?
Glucosyl-3-phosphoglycerate synthase, GpgS.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
Protein: RSMJ_AERS4
Sequence: MQILLEDPTKAAQAQVLASQLNQTDYPQFALVFTPERLELRKLDEPKLGAVYVDFVEGAVAHRRKFGGGRGQSIAKAVGLKAGAMPTVVDATAGLGRDAFVLASLGCKVTLIERSPVVAALLQDGLMRAAQDPEIGPWVSERMRLLQGPAVDNLLALPERPDVIYLDPMFPHKQKSALVKKEMRVFQSLVGPDLDADALLPAALQMADKRVVVKRPDYAGWLNEHKPSMAIETKSNRFDVYVMAALAAG
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DF270_ARATH
Sequence: MMSSKSHFVALLLIIFLIVNVQSTRIMDDSSDCVFKGPCQRRSDCYERCGLKPPSRAALCQPMGLQGRVCCCL
What are the official names of this protein?
Putative defensin-like protein 270.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL4_PELPD
Sequence: MPSIAVYNMNRQQVGELQLADDVFNADVKEHLMHLALRIQLANRRAGTVKTKTRSEVAGSGKKPFKQKGTGNARQGCVRAPQYPGGGVAFGPQPKEYHLSMNKKARKSAICSALSLQCKNNRITVMDKLDFSSISTKAFVDFMKRFEIERSLIITDDFSNNLQLSCRNVPHVKLLKHDALNIHDILKYKNIIFTQGAVQSVEGVLNK
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: KRP3_ORYSJ
Sequence: MGKYLRSSCKQQQQPSSPAAVASVAAAAVSSYSYLTLRSGRRVPAAAAAAGGSACRRRHRRGGRRGCAKNGAGSARACGARSPTSSASSGQRRRCEAVECSHGGGRAELSRSPPLGNSVVVVSGDVVSGERKSLKPNSCSREVAAEHAGEHKHNPAAAAAAGRRPPLSPPEAEIEAFFAAAELAERRRFAEKYNYDIALDRPLQGRYEWEPTVPNFDVAKDVTDM
What are the official names of this protein?
Cyclin-dependent kinase inhibitor 3, KIP-related protein 3.
What is the protein family that this protein belongs to?
Belongs to the CDI family. ICK/KRP subfamily.
Protein: AASD1_MOUSE
Sequence: MAFLCQRDSYAREFTTTVVSCSPAELQTDASGGKKEVLSGFHVVLEDTLLFPEGGGQPDDRGTINDISVLRVTRRGAQADHFTESPLSPGSQVQVRVDWERRFDHMQQHSGQHLITAVADLLFGLKTTSWELGRLRSVIELDSPSVTAEQVAAIEQSVNQKIRDRLPVSVRELSLDDPEVEQVRGRGLPDDHAGPIRVVTIEGVDSNMCCGTHVSNLSDLQVIKILGTEKGKKNKSNLIFLAGNRVLKWMERSHGSEKALTSLLKCGVEDHVEAVKKLQNATKLLQKNNLNLLRDLAVHTAHSLRSSPAWGGVVTLHRKEGDSEFMNIIANEIGSEETLLFLTVGDEKGAGLFLLAGPAEAVETLGPRVAEVLEGKGAGKKGRFQGKATKMSRRAEAQALLQDYVSTQSAEE
What is the function of this protein?
Functions in trans to edit the amino acid moiety from incorrectly charged Ser-tRNA(Ala).
What are the official names of this protein?
Alanyl-tRNA editing protein Aarsd1, Alanyl-tRNA deacylase alaX, AlaX, AlaXp-II, Alanyl-tRNA synthetase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSUH2_HUMAN
Sequence: MDRDLNEDDSVVDLSFEAESPLAPPTELLERLPSYDWLLQGGRGQIFFPPLEAPGRPQEQRSWPSFLEHRVPAMTEEVAREALLSFVDSKCCYSSTVAGDLVIQELKRQTLCRYRLETFSESRISEWTFQPFTNHSVDGPQRGASPRLWDIKVQGPPMFQEDTRKFQVPHSSLVKECHKCHGRGRYKCSGCHGAGTVRCPSCCGAKRKAKQSRRCQLCAGSGRRRCSTCSGRGNKTCATCKGEKKLLHFIQLVIMWKNSLFEFVSEHRLNCPRELLAKAKGENLFKDENSVVYPIVDFPLRDISLASQRGIAEHSAALASRARVLQQRQTIELIPLTEVHYWYQGKTYVYYIYGTDHQVYAVDYPERYCCGCTIV
What is the function of this protein?
Plays a role in odontogenesis.
What are the official names of this protein?
Protein SSUH2 homolog, Protein ssu-2 homolog.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DIRA_CAEEL
Sequence: LLDTDFSIEATAATTTAGSGSKVAEASTSDYRVAVFGAGGVGKSSITQRFVKGTFNENYVPTIEDTYRQVISCNQKNVCTLQITDTTGSHQFPAMQRLSISKGNAFILIYSVTNKQSFAELVPIIEMMKEVKGNAIAETPIMLVGNKKDEESKREVSSNSGQKVATNMECGFIETSAKNNENITELFQQLLALEKKRQLALTMDDPDGKNGKKKGCHIM
What is the function of this protein?
Displays low GTPase activity and exists predominantly in the GTP-bound form (By similarity).  Together with epac-1, may regulate acetylcholine release at the neuromuscular junctions probably downstream of G-protein gsa-1 and adenylate cyclase acy-1 (PubMed:22897658).
What are the official names of this protein?
GTP-binding protein drn-1, Di-Ras/Rig/Noey2 Ras-like protein homolog.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Di-Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: PPNP_CUPMC
Sequence: MSQFDNVSVVKKANLYFDGKCVSHTVTFADGTRKTLGVIFPAALTFNTGAPEIMEINAGVCRVRLAGSDEWKTYGAGQQFDVPGNSSFDIEVTETLDYVCHFG
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: MOAA_PEPAC
Sequence: MDNKSVLLDGYGRRINYLRISVTDRCNLRCMYCMPQEGIPKRAHHDIMTLEELQEVAVALVELGIDKIRITGGEPLVRKGIVGLVRELSKCEGLNEITLTTNGLLLSEYARELKAAGLKRVNISLDTLNPQKFEYITRGGSLEKVLEGIKEAQSVGLTPIKLNTVLIGGFNDDEIEDFVALTVDNEIDVRFIELMPYRTGSRLWSLEKFISSDSVLKKVPSLEKIKSEDISSPAEYYRIPGALGKVGLINPITCKFCENCNRLRLTSDGKLKLCLHSDSEIDLAGPLRRGEDIRGIVLDEIKNKPREHSLEDGEYIKRDMFKIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.