PharMolix/UniProtQA huggingface dataset:
Protein: RL22_CORGL
Sequence: MSDNITSASATARFVRVSPMKARRVIDLVRGKTVVEALSILKYAPQAASEPVAKVVASAAANAENNFGLDPRTLVISEAYANEGPTMKRFQPRAQGRAFQIRKRSSHITVVVESQKEGAN
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: SWC4_CRYNJ
Sequence: MSAQDVRSILSLPPSTPLPTLSSSKKVPVPRKPDGITRELYALIGDNAPSLADAQASLAAVKYREKPALKGKKVHWEWTKFTPAARRDNPVRLGHWARITDSDPNDSVEYFGKFNLHGPSVMEYSQFEYDQHLVDPNWTLQETEYLFELLKEYDLRFIVAADRYAYVSPEGEKRKRSVEDMKDRYYTICRRLIRTRTASDPVHQQHLIQAYAFDKAREIKRKQYASDLFHLTPAEIAEEEALYVEITRMQQNERRFRADRDELMRSVMGLDSGLVEVDQSAMENAIGVDKNKKKRKAEDESAAPSPAPTPKKPAPNAGFDNSRCIYHLPTPSNANSLTSHLSQKHPPHQQAFLRGSRLPLPKPTAAGRITDLLAELGLSANRLVMPTRQNMEVFEGLLNAAAALVEMRRQVNRVEQELRVVRMQKEGLMPVTTNPSARVKGEAGVVTGGSEATVKAVTPVKEC
What is the function of this protein?
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling.  Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A.  The NuA4 complex is also involved in DNA repair (By similarity).
What are the official names of this protein?
SWR1-complex protein 4.
What is the protein family that this protein belongs to?
Belongs to the SWC4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DPO4_YERP3
Sequence: MRKIIHVDMDCFFAAVEMRDDPRLRDIPLAIGGSKERRGVISTANYPARRYGVRSAMPTAMAFKLCPQLTLLPGRMAAYKEASQHIREIFARYTPLIEPLSLDEAYLDVSDSLACGGSATLIAQEIRQSIASELNLTASAGIAPIKFLAKIASELNKPNGQYVITPNQIQPFLQDLPLSKIPGVGAVTAKRLQALGLVTCGEIQKYPLAELLKHFGKFGRVLWERSHGIDEREISPDRLRKSVGVEKTLAEDIYDWESCEALIEELYLELETRLRKVKPDLHIARQGVKLKFHDFQQTTQEHTWPVLNKADLLQIAHAAWNERRAERGVRLVGLHVTLLDPQLERQLLLDWG
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UDB16_RABIT
Sequence: LLLLLQLSCCFSSGSCGKVLVWPMEFSHWMNMKTILDALVQRGHAVTVLRSSASILVNSNDESGITFETFPTTSTKDEMEAFFMYWLNKLTNDVSKDALWEYFQTWQKFFMEYSDNYENICKDLVLNKKIMAKLQESRFDVVLADPIAPCGELLAELLNRPLVYSVRFTPGYTYEKYSGGLLFPPSYVPVIMSDLSGQMTFMERVKNMLWMLYFDFWFQMLNVKRWDQFCSEVLGRPVTFSELVGKAEIWLIRSYWDLEFPRPLLPNSYFVGGLHCKPAQPLPKEMEEFVQSSGEEGVVVFSLGSMISNLTEERANVIASTLAQLPQKVLWKFDGKKPDNLGTNTQLYKWIPQNDLLGHTVSKAFITHGGANGVFEAIYHGIPMVGLPLFADQHDNLAHMRAKGAAIRLDWKTMSSSDFLNALKTVINDPSYKEKAMTLSRIHHDQPMKPLDQAIFWIEFVMRHKGAKHLRVAAHDLTWFQYHSLDVIGFLLACLTITTYLVIKCWLLVYQNILMTGKKKKRD
What is the function of this protein?
UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.  Acts on small phenolic agents such as 2-beta-naphthol and 4-methylumbelliferone as well as bulky phenolic compounds like 2-hydroxy- and 4-hydroxybiphenyl.  In contrast to 2B13 it is active toward 4-hydroxyesterone.
What are the official names of this protein?
UDP-glucuronosyltransferase 2B16, UDPGT 2B16.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
What are the subcellular locations of this protein?
Microsome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: IND2_STRGR
Sequence: MKLDDKRILIIGAGEVGTAVAEDLVNRSDPTEIIIHTSRQQTMDMRVGHLKEMAGPRTLLTGSWGDIFAPYELTHRSRSEINDRNVRLALAEFFLQPSGEAQLRRTTIYELISRHRPHIVIDAVNSASVCTYTEDPHQTCGELLDLARGTGGPRTAEAPAELPAVTPDIADVATDALLSLSTPILHRYVDSLRRAMADFQVERFIKVSTTGLGGMGYNCPYTHGSVTEFGLSDALVGKIGSAGVLHQLLWNLHHTAGCDVRLVIPAALIGWESVRHGAYTSRGRPVALQDCSRPLPLHLDRPLGEHAAASSVAEPAAEDEPSAEMVHVPAGDNSTYSRAEMSLSTALGQFESVTREEVAAAVLDTLLGSTRFDLFTAMDTASLQSSYLAAQMRTSTLTSMRQLEKAYDRPSIVSGNLGPTISKDLLELHVLCTAAGSLEQARTMSTTVLASSASALVREDVYLRQQALSIGLAVLLPDDQWLAGPRLSVPSRIDPEAKVTRADIDDWSRQGWVDLRPARILHWQENLRRIEQDASAGKTAFALDDTAYDVGEVLAYHYKLTGQARRIKGL
What is the function of this protein?
Involved in the biosynthesis of the antibiotic indolmycin, an inhibitor of the bacterial tryptophan-tRNA synthetases.  Catalyzes the NADH-dependent reduction of beta-methylindolepyruvate to yield indolmycenate.
What are the official names of this protein?
Beta-methylindole-3-pyruvate reductase, Beta-methylindolepyruvate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily.
Protein: TRPE2_HALSA
Sequence: MPDSAALATDPAAFRDAAGDATAPTRAVVEARLPVTDPFAAYRRARGDAPSFHYETTGGSDGWGYFGVDPASMLRADGAGALDTVQAAVGARLARVGCDVPHPGGLFGWLSYDIARELEAIPDTTTDARGLPRLQLGVYPTIAAWREPFTPGDDLRLIAAVPVDEYTPDGAFEAGRDRVQSLAAAIRDGDPAVGPPPADSPAPFESVAGRAAFESRVRRIQDAIRDGDTFQANVSHRLDAPAAVHPVAVFEALRDTNPAPYSGIVEFPGVDLVSASPELLLARRGRELTTEPIAGTRPRGATPAEDDAARAALRADDKERAEHAMLVDLERNDLGKVSEYGSVAVPDYRRVDAYSEVLHLVSEVTGRLRDSCSLRDAIAAVFPGGTITGAPKPRTMALIDTVEATRRGPYTGSLAAIGFDGDATLSITIRTLVRRAATYHLRVGAGIVHDSTPAAEYDETLAKARALVTALGDAGGIGRVADTTPDNS
What are the official names of this protein?
Anthranilate synthase component 1 2, Anthranilate synthase component I 2.
What is the protein family that this protein belongs to?
Belongs to the anthranilate synthase component I family.
Protein: MIB1_DANRE
Sequence: MTTGRNNRVMMEGVGARVIRGPDWKWGKQDGGEGHVGTVRSFESPEEVVVVWDNGTAANYRCSGAYDVRILDSAPTGIKHDGTMCDTCRQQPIIGIRWKCAECTNYDLCTTCYHGDKHHLRHRFYRITTPGSERVLLESRRKSKKITARGIFAGGRVVRGVDWQWEDQDGGNGRRGKVTEIQDWSAASPHSAAYVLWDNGAKNLYRVGFEGMSDLKCVQDAKGGTFYRDHCPVLGEQNGNRNPGGLQIGDLVNIDLDLEIVQSLQHGHGGWTDGMFETLTTTGTVCGIDEDHDIVVQYPSGNRWTFNPAVLTKANVVRSGEVAAGAEGGSSQFMVGDLVQICYDIDRIKLLQRGHGEWAEAMLPTLGKVGRVQQIYSDSDLKVEVCGTSWTYNPAAVTKVAPAGSAVTNASGERLSQLLKKLFETQESGDINEELVKAAANGDLAKVEDILKRPDVDVNGQCAGHTAMQAASQNGHVDVLKLLLKHSVDLEAEDKDGDRAVHHASFGDEGSVIEVLHRGGADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDMLSVLLEAGADVTITNNNGFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELLVHQGNANLDVQNVNQQTALHLAVERQHTQIVRLLVRAEAKLDVQDKDGDTPLHEALRHHTLSQLRQLQDMQDVSKVEPWEPSKNTLIMGLGTQGAEKKSAASIACFLAANGADLTIRNKKGQSPLDLCPDPSLCKALAKCHKEKTSGQVGSRSPSLNSNNETLEECMVCSDMKRDTLFGPCGHIATCSLCSPRVKKCLICKEQVQSRTKIEECVVCSDKKAAVLFQPCGHMCACENCASLMKKCVQCRAVVERRTPFVLCCGGKGMEDATDDEDLTGGSNSMAGGSQDLLQPNNLALSWSSGNIPALQRDKDNTNVNADVQKLQQQLQDIKEQTMCPVCLDRLKNMIFMCGHGTCQLCGDRMSECPICRKAIERRILLY
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins.  Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors.  It thereby participates in many processes regulated by the Notch signaling pathway, such as midline cell fate specification prior to germ layer formation, patterning of sensory cell differentiation in the ear, neurogenesis of the hindbrain and commitment to a secretory fate in the intestine.  Essential for early embryonic development.
What are the official names of this protein?
E3 ubiquitin-protein ligase mib1, Protein mind bomb, RING-type E3 ubiquitin transferase mib1.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Cytoplasm. Cell membrane. Note=Localizes to the plasma membrane.
Protein: UVRA_CHLPN
Sequence: MKSLPVYVSGIKVRNLKNVSIHFNSEEIVLLTGVSGSGKSSIAFDTLYAAGRKRYISTLPTFFATTITTLPNPKVEEIHGLSPTIAIKQNHFSHYSHATVGSTTELFSHLALLFTLEGQARDPKTKEVLDLYSKEKVLSTIMELSEGVQISILAPLLRKDIAAIHEYAQQGFTKVRCNGTIHPIYSFLTSGIPEDCSVDIVIDTLIKSENNIARLKVSLFTALEFGEGHCSVLSDEELMTFSTKQQIDDVTYTPLTQQLFSPHALESRCSLCQGSGIFISIDNPLLIDENLSIKENCCSFAGNCSSYLYHTIYQALADALNFNLETPWKDLSPEIQNIFLRGKNNLVLPVRLFDQTLGKKNLTYKVWRGVLNDIGDKVRYTTKPSRYLSKGMSAHSCSLCKGTGLGDYASVATWEGKTFTEFQQMSLNNWHVFFSKVKSPSLSIQEILQGLKQRLSFLIDLGLGYLTPNRALATLSGGEQERTAIAKHLGGELFGITYILDEPSIGLHPQDTEKLIGVIKKLRDQGNTVILVEHEERMISLADRIIDIGPGAGIFGGEVLFNGKPEDFLMNSSSLTAKYLRQELTIPIPESREAPTSWLLLTEATIHNLKNLSIRLPLARLIGVTGVSGSGKSSLINNTLVPAIESFLKQENPKNLHFEWGCIGRLIHITRDLPGRSQRSIPLTYIKAFDDIRELFASQPRSLRQGLTKAHFSFNQPQGACIQCQGLGTMTISDDDTPIPCSECQGKRYHSEVLEILYEGKNIADILDMTAYEAEKFFISHPKIHEKIHALCSLRLDYLPLGRPLSTLSGGEIQRLKLAHELLFASPKQTLYVLDEPTTGLHTHDIQALIEVLLSLTYLGHTVLVIEHNMHVVKVCDYVLELGPEGGDLGGYLLASCTPKDLIQLNTPTAKALAPYIEGSLDIPVVKSEPPSSPKSCDILIKDAYQNNLKHIDLALPRNSLIAIAGPGASGKHSLVFDILYASGNIAYAELFPPYIRQGLLKETPLPSVGEVKGLSPVISVRKCSSSNRSYHTIASALGLSNGLEKLFAILGEPFSPLTEEKLSKTTPQTIIDSLLKSYKDDYVTITSPIPLGSDLEIFLQEKQKEGFIKLYSEGNLYDLDERLPLNLIEPAIVIQHTKVSPKNSSSLLSAISVAFSLSSEIWIYISQKKQRKLSYSLGWKDKKGRLYPEITHQLLSSDHPEGRCLTCGGRGEILKISLEEHKEKIAHYTPLEFFSLFFPKSYMKPVQKLLKDENASQPLKLLTTKEFLNFCRGSSEFPGMNALLMEQLDTESDSPLIKPLLALTSCPACKGSGLNDYANYVRINNTSLLDIYQEDATFLESFLNTIGTDDTRSIIQDLMNRLTFISKVGLSYITLGQRQDTLSDGENYRLHLAKKISINLTNIVYLFEEPLSGLHPQDLPTIVQLLKELVANNNTVIATDRSCSLIPHADHAIFLGPGSGPQGGFLMDSDTEVCPSVDLHANVPQTEVCPKAPLSISKANHTRGSDRTLKVNLSIHHIQNLKVSAPLHALVAIGGVSGSGKTSLLLEGFKKQAELLIAKGTTTFSDLVVIDSHPIASSQRSDISTYFDIAPSLRAFYASLTQAKALNISSTMFSTNTKQGQCSDCQGLGYQWIDRAFYALEKRPCPTCSGFRIQPLAQEVLYEGKHFGELLHTPIETVALRFPFIKKIQKPLKALLDIGLGYLPIGQKLSSLSVSEKTALKTAYFLYQTPETPTLFLIDELFSSLDPIKKQHLPEKLRSLINSGHSVIYIDHDVKLLKSADYLIEIGPGSGKQGGKLLFSGSPKDIYASKDSLLKKYICNEELDS
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrA is an ATPase and a DNA-binding protein.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity).
What are the official names of this protein?
UvrABC system protein A, UvrA protein, Excinuclease ABC subunit A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. UvrA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFGM_SCHJY
Sequence: MFMRLKVLEMNSIRRQTLLRQFTNVYNVVSRSARLCSQAIPKRLFYSTGSRANSIPDALSRLRNIGISAHIDSGKTTFTERVLFYTGRIKDIHEVRGKDNVGAKMDSMELEREKGITIQSAATYCNWKRKQKDGDEQDYIINIIDTPGHIDFTIEVERALRVLDGAVLILCAVSGVQSQTITVDRQMRRYNVPRITFINKMDRMGANPWRAIEQLNAKLRIAAAAVQIPIGSEDNLEGVVDLIHMQSIYNRGKKGEKVEITGSIPEHLKELANEKRALLIETLANIDEEIGELYVMEETPSPEQLMSAIRSATLSRQFTPVFMGSALANIGVQPLLDAVCDYLPNPSDVTNTALDVNQGEKSVTLHTDYNEPLVALAFKLEDGRFGQLTYMRVYQGVLKRGNQITNVNSGKRIKVPRLVLLHSDEMEDVEEAPAGSICAMFGVDCASGDTFTDGSIKYVMSSMYVPEPVVSLSIKPKNKDSPNFSKALARFQREDPTFRVHIDKESNETIISGMGELHLEIYLERLAREYRTECITGKPRVAFRETITTKAPFSYLHKKQSGGAGQYAKVEGYIEYMEPKEDGNGRLVDHEFVNHVVGGAIPSQYIPACEKAFKECLERGFLTGHPIKNCRLVLEDGAAHSVDSSELAFRVALTHAFRQAFMAAKPIVLEPIMNVTVTAPVDDQGVVIGNLDKRKATIVNTDIGEEEFTLQAEVPLNSMFSYSSDIRSSTQGKGEFTMEFLKYLPAPGYVQKELIAEYEKQHK
What is the function of this protein?
Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, mitochondrial, EF-Gmt, Elongation factor G 1, mitochondrial, mEF-G 1, Elongation factor G1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MSH2_CHLAE
Sequence: MAVQPKETLQLESAAEVGFVRFFQSMPEKPTTTVRLFDRGDFYTAHGEDALLAAREVFKTQGVIKYMGPAGAKNLQSVVLSKMNFESFVKDLLLVRQYRVEVYKNRAGNKASKENDWYLAYKASPGNLSQFEDILFGNNDMSASIGVVGVKMSTVDGQRQVGVGYVDSTQRKLGLCEFPDNDQFSNLEALLIQIGPKECVLPGGETAGDMGKLRQIIQRGGILITERKKADFSTKDIYQDLNRLLKGKKGEQMNSAVLPEMENQVAVSSLSAVIKFLELLSDDSNFGQFELTTFDFSQYMKLDIAAVRALNLFQGSVEDTTGSQSLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERLNLVEAFVEDAELRQTLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPNVIQALEKHEGKHQKLLLAVFVTPLTDLRSDFSKFQEMIETTLDMDQVENHEFLVKPSFDPNLSELREIMNDLEKKMQSTLISAARDLGLDPGKQIKLDSSTQFGYYFRVTCKEEKVLRNNKNFSTVDIQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLAQLDAVVSFAHVSNGAPVPYVRPAILEKGQGRIILKASRHACVEVQDEITFIPNDIYFEKDKQMFHIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLKGVSTFMAEMLETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGAFCMFATHFHELTALANQIPTVNNLHVTALTTEETLTMLYQVKKGVCDQSFGIHVAELANFPKHVIECAKQKALELEEFQYIGESQGYDMEPAAKKCYLEREQGEKIIQEFLSKVKQMPFTEMSEENITIKLKQLKAEVIAKNNSFVNEIISRIKVTT
What is the function of this protein?
Component of the post-replicative DNA mismatch repair system (MMR).  Forms two different heterodimers: MutS alpha (MSH2-MSH6 heterodimer) and MutS beta (MSH2-MSH3 heterodimer) which binds to DNA mismatches thereby initiating DNA repair.  When bound, heterodimers bend the DNA helix and shields approximately 20 base pairs.  MutS alpha recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA.  MutS beta recognizes larger insertion-deletion loops up to 13 nucleotides long.  After mismatch binding, MutS alpha or beta forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.  Recruits DNA helicase MCM9 to chromatin which unwinds the mismatch containing DNA strand.  ATP binding and hydrolysis play a pivotal role in mismatch repair functions.  The ATPase activity associated with MutS alpha regulates binding similar to a molecular switch: mismatched DNA provokes ADP-->ATP exchange, resulting in a discernible conformational transition that converts MutS alpha into a sliding clamp capable of hydrolysis-independent diffusion along the DNA backbone.  This transition is crucial for mismatch repair.  MutS alpha may also play a role in DNA homologous recombination repair.  In melanocytes may modulate both UV-B-induced cell cycle regulation and apoptosis.
What are the official names of this protein?
DNA mismatch repair protein Msh2, MutS protein homolog 2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: MURG_RHOE4
Sequence: MSGNKSALSVVVAGGGTAGHIEPALAVADAVKAAQPDTRITALGTARGLETTLVPARGYTLELIPPVPLPRKPTMDLVKLPTRILASVRKTREVLDSVDADVIVGFGGYVALPAYLAARGGVLRRRRKIPIVIHEANASAGIANKIGARLATRVLAAVPGSGVKNRGDQDAEIVGIPVRASIANFDRAGLRSQAREYFGLPQDGPVLLVFGGSQGAKSLNDAVSGAAEELAKAGISVLHAHGPKNSLEVTQYSETAPYVAVPYLSRMDLAYAAADATICRSGAMTVAEVSAVGLPAVYVPLPHGNGEQELNAKPVVAAGGAIIVSDNELTPTFVAGTVVPMLSDSARLDKMSSGAANVGHRTAATEIARIVLDIAAKENAVQENARGNR
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: KGUA_BURMA
Sequence: MTDSNRDGAAAHSLHAGVYPGNLFMVVAPSGAGKSTLVNALLSKDPEIRLSISYTTRKPRPGEQDGQHYHFTTVEDFRERHARHEFLESAEVHGNYYGTSRVWIEEQMKIGHDVLLEIDWQGAQQVKKQFRNAVGIFILPPSLAALEERLKKRGQDEPNVITRRLLAAGSEIAHAAEAQYVVINETFEHALAELECIVAATRLRFTSQYARHAELFVELGIHLPHAE
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MKLN1_PONAB
Sequence: MAAGGAVAAAPECRLLPYALHKWSSFSSTYLPENILVDKPNDQSSRWSSESNYPPQYLILKLERPAIVQNITFGKYEKTHVCNLKKFKVFGGMNEENMTELLSSGLKNDYNKETFTLKHKIDEQMFPCRFIKIVPLLSWGPSFNFSIWYVELSGIDDPDIVQPCLNWYSKYREQEAIRLCLKHFRQHNYTEAFESLQKKTKIALEHPMLTDIHDKLVLKGDFDACEELIEKAVNDGLFNQYISQQEYKPRWSQIIPKSTKGDGEDNRPGMRGGHQMVIDVQTETVYLFGGWDGTQDLADFWAYSVKENQWTCISRDTEKENGPSARSCHKMCIDIQRRQIYTLGRYLDSSVRNSKSLKSDFYRYDIDTNTWMLLSEDTAADGGPKLVFDHQMCMDSEKHMIYTFGGRILTCNGSVDDSRASEPQFSGLFAFNCQCQTWKLLREDSCNAGPEDIQSRIGHCMLFHSKNRCLYVFGGQRSKTYLNDFFSYDVDSDHVDIISDGTKKDSGMVPMTGFTQRATIDPELNEIHVLSGLSKDKEKREENVRNSFWIYDIVRNSWSCVYKNDQAAKDNPTKSLQEEEPCPRFAHQLVYDELHKVHYLFGGNPGKSCSPKMRLDDFWSLKLCRPSKDYLLRHCKYLIRKHRFEEKAQMDPLSALKYLQNDLYITVDHSDPEETKEFQLLASALFKSGSDFTALGFSDVDHTYAQRTQLFDTLVNFFPDSMTPPKGNLVDLITL
What is the function of this protein?
Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1 (By similarity).  Required for internalization of the GABA receptor GABRA1 from the cell membrane via endosomes and subsequent GABRA1 degradation.  Acts as a mediator of cell spreading and cytoskeletal responses to the extracellular matrix component THBS1 (By similarity).
What are the official names of this protein?
Muskelin.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytosol. Nucleus, nucleoplasm. Cell projection, ruffle. Cytoplasm, cell cortex. Synapse. Postsynapse. Note=Colocalizes with GABRA1 at synapses and in postsynaptic regions. Colocalizes with actin fibers in the cell cortex.
Protein: AROA_LEGPC
Sequence: MLNFISKPVVCLKGEITVPGDKSISHRSIIFGAIAIGTSVIDGFLDGEDCIATLKAFQSMGVRIEGPDKQRVIIHGVGKYGLKQPQNIIDCGNSGTSMRLLAGLLAAQQFDSQLTGDESLLKRPMLRISRPLSQMGADVTTQDGKPPILIKGGKKLNGIHYVMPEASAQVKSCLLLAGMYAEGQTKITENAVSRDHTERMLRTFSYPVQIQDGVIVIDRNGECHGTRLNIPGDISSAAFFIVAASITPGSDILIRNVGINPTRTGIIHILTEMGADIKVLNQRAYGEEPVADLHIRYSQLKGIDIPVSMVPLAIDEFPVIFIAAACAQGKTTLHGAKELRLKESDRIGAMVDGLNQLGVHAEGFDDGILIEGGSIQGGEVNSRGDHRIAMSFAIAGAVASAPVTIKNCANVATSFPSFVTTANILHFQIEEYS
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTNK_ECOLI
Sequence: MIKIGVIADDFTGATDIASFLVENGLPTVQINGVPTGKMPEAIDALVISLKTRSCPVVEATQQSLAALSWLQQQGCKQIYFKYCSTFDSTAKGNIGPVTDALMDALDTPFTVFSPALPVNGRTVYQGYLFVMNQLLAESGMRHHPVNPMTDSYLPRLVEAQSTGRCGVVSAHVFEQGVDAVRQELARLQQEGYRYAVLDALTEHHLEIQGEALRDAPLVTGGSGLAIGLARQWAQENGNQARKAGRPLAGRGVVLSGSCSQMTNRQVAHYRQIAPAREVDVARCLSIETLAAYAHELAEWVLGQESVLAPLVFATASTDALAAIQQQYGAQKASQAVETLFSQLAARLAAEGVTRFIVAGGETSGVVTQSLGIKGFHIGPTISPACRG
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of 3-oxo-tetronate to 3-oxo-tetronate 4-phosphate.
What are the official names of this protein?
3-oxo-tetronate kinase, 3-dehydrotetronate 4-kinase.
What is the protein family that this protein belongs to?
Belongs to the four-carbon acid sugar kinase family.
Protein: SERPH_PONAB
Sequence: MRSLLLLSAFCLLEAALAAEVKKPAAAAAPGTAEKLSPKAATLAERSAGLAFSLYQAMAKDQAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQLRDEEVHAGLGELLRSLSNSTARNVTWKLGSRLYGPSSVSFADDFVRTASSTTTASTPRSTSATSAALQSINEWAAQTTDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHRTGLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKIWMGKMQKKAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFELDTDGNPFDQDIYGREELRSPKLFYADHPFIFLVRDTQSGSLLFIGRLVRPKGDKMRDEL
What is the function of this protein?
Binds specifically to collagen.  Could be involved as a chaperone in the biosynthetic pathway of collagen (By similarity).
What are the official names of this protein?
Serpin H1, Collagen-binding protein, Colligin.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: Y263_PSEA6
Sequence: MLTWALTFFVLGVIAAVFGFGGVIGVAASIAKVIFLLCVAFVVLFSVLAFKQHKRHK
What are the official names of this protein?
UPF0391 membrane protein Patl_0263.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL33_MOOTA
Sequence: MRVGITLACTECKRRNYISTKNKKNDPDRIELKKYCSFCGRHTVHKETK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RL22_GEOSW
Sequence: MQAKAVARTVRIAPRKARLVIDLIRGKEVGEAVAILRHTPKAASPIIEKVLKSAVANAEHNYDMDVNKLVITEAYVDEGPTLKRFRPRAMGRASAINKRTSHITIVVSEKKEG
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: VEMP_CVPIA
Sequence: MFMADAYLADTVWYVGQIIFIVAICLLVIIVVVAFLATFKLCIQLCGMCNTLVLSPSIYVFNRGRQFYEFYNDVKPPVLDVDDV
What is the function of this protein?
Plays a central role in virus morphogenesis and assembly.  Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport.  Also plays a role in the induction of apoptosis.
What are the official names of this protein?
Envelope small membrane protein, E protein, sM protein.
What is the protein family that this protein belongs to?
Belongs to the betacoronaviruses E protein family.
What are the subcellular locations of this protein?
Host Golgi apparatus membrane; Single-pass type III membrane protein. Note=The cytoplasmic tail functions as a Golgi complex-targeting signal.
Protein: TPB_PELSA
Sequence: FLGTINLSLCEQERDADEEERRDEPDESDVEVEKRFLPIVTNLLSGLLGK
What is the function of this protein?
Amphipathic alpha-helical peptide with no antimicrobial activity (PubMed:18584916, PubMed:18795798).  Does not display anti-leishmania activity (PubMed:18584916).  Does not show hemolytic activity (LC(50)>116 uM) (PubMed:18584916, PubMed:18795798).
What are the official names of this protein?
Temporin-SHb, Temporin-1Sb, Temp-1Sb.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Temporin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PHCB_PORPU
Sequence: MLDAFAKVVAQADARGEFLSNTQLDALSSMVAEGNKRLDVVNKINSNASAIVTNSARALFAEQPQLIQPGGNAYTNRRMAACLRDMEIVLRYVSYAMIAGDSSVLDDRCLNGLRETYQALGTPGSSVSVAVQKMKEASVALANDLTGTPQGDCSALVAELGSYFDRAAVSVV
What is the function of this protein?
Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex (phycobilisome, PBS).  Phycocyanin is the major phycobiliprotein in the PBS rod.
What are the official names of this protein?
C-phycocyanin beta chain.
What is the protein family that this protein belongs to?
Belongs to the phycobiliprotein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side. Note=Part of the phycobilisome rod.