PharMolix/UniProtQA huggingface dataset:
Protein: RK33_BRADI
Sequence: MAKGKDVRIRVILECISCVRKGANEESTGISRYSTEKNRHNTPGQLEFKKFCRYCRKHTTHHEIKK
What are the official names of this protein?
50S ribosomal protein L33, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HAL3_ORYSJ
Sequence: MTTSESVQETLGLDFPHPSKPRVLLAASGSVAAIKFESLCRSFSEWAEVRAVATKASLHFIDRTSLPSNIILYTDDDEWSTWKKIGDEVLHIELRKWADIMVIAPLSANTLAKIAGGLCDNLLTCIVRAWDYSKPLFVAPAMNTFMWNNPFTSRHLETINLLGISLVPPITKRLACGDYGNGAMAEPSVIDSTVRLACKRQPLNTNSSPVVPAGRNLPSS
What is the function of this protein?
Catalyzes the decarboxylation of 4'-phosphopantothenoylcysteine to 4'-phosphopantetheine, a key step in coenzyme A biosynthesis (PubMed:19232050, PubMed:19543273).  Involved in salt and osmotic tolerance, and light-regulated plant growth (PubMed:19543273).  Trimerization of HAL3 recruits and activates the E3 ubiquitin-protein ligase HIP1, which leads to the degradation of cell cycle suppressors, resulting in enhancement of cell division and plant growth (PubMed:19543273).  HAL3 function in cell division seems to be independent from its PPC decarboxylase activity (PubMed:19543273).  Acts as a positive regulator of flowering by binding to HD1 in the dark (PubMed:26537047).
What are the official names of this protein?
Phosphopantothenoylcysteine decarboxylase, PPCDC, Halotolerance protein HAL3, OsHAL3.
What is the protein family that this protein belongs to?
Belongs to the HFCD (homooligomeric flavin containing Cys decarboxylase) superfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y3052_BACAC
Sequence: MNTPVSVNEKKDFVKWFLNNYQLKQRECVWILNYLMSHDQLMHKVHFVEHAKYCPRGLVMSANCVKDTPFHFFKQNVMTTDAEKSFHDIRLNRDEDIYIQLNFKSSFQNANYVAVLEENPYLPKHIEVNEKDRLLAERFLEESVFSFRRERLLKQIDEALDKQDKEAFHRLTAELKML
What are the official names of this protein?
UPF0302 protein BAMEG_3052.
What is the protein family that this protein belongs to?
Belongs to the UPF0302 family.
Protein: PYRG_ENCCU
Sequence: MKYVIVSGGVISGVGKGIVSSSIGALLKSRGHVVTHFKIDPYLNYNAGRMHPYEHGEVYVLDDGHECDMDFGNYERFNGIKLSGANSIPGGRLLHDIVKCEREGSFLGKTLQINPHIIDEVIRRIRAVADTPVESFGGGQAAVPDVVVVELGGTVGEYESSIYTEALAKFQYVVGKANCAFVSVDYIVELETGEQKTKGIQMGCRNFRRFGLNYDIVICRGRREPNMETRRKISTSCWVKEENVLGLPNLESVYLAPMFLEKHGIVEALNRILGLDDKGMDRRMLDIFSMVGRRHRDGVRIGIVGKYAPEFDSYTSLVNALKFSGAHIGVNVEIVWINSESYSVCDFERCDGVVIPGGFGARGISGKIEAIRHARENGVPLLGICLGYQLSVIEMCRNILGMSDAFSEEFQPSGKNLVVRFISDENGVVDKRLRVGGYGVELRDGLVKKLYGGVETVRERHRHRFEVAQEKVRGLLQHGVRFVGFSSGGKKINVFEVESHPFFVGVQFHPEFNARPDRPHPLITGLVSASYERSK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.
What are the official names of this protein?
CTP synthase, CTP synthetase, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: TGT_DESVV
Sequence: MTTPGTFEIHATDGAARTGCLHTAHGIVRTPIFMPVGTVGSVKAIAPDDLEAIGAEIILGNTYHLYLRPGDELVARRGGLHEFNAWRKPILTDSGGFQVFSLSGLRRIAEEGVEFRSHLDGSKHLFTPEKVVSIQRNLNSDIMMVLDECVPYGADRTYTEKSVGLTTRWAKRCRDAYPKGAAGNLLFGITQGGFFKDLRTRSIGELTDIDFDGFALGGLSVGEPKAEMMDLLYHSAPLLPADKPRYLMGVGTPLDIINGIAAGVDMFDCVLPTRNARNGTLYTSLGKLNIKRREFAEDDGPLDPACSCYTCRTFSRAYLRHLYTAKELLAFRLNSIHNLTYFLDLVRGARAAIAAGRFAEYKRSFEAIYPEEVVA
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: RPB6_ASFK5
Sequence: MADNDNEDSIMDDLVEEYVETEEENFVDSEEESEDKDEIVESPSICEGFVQASSQTLVVIPDNERITSNVLTTFEATRLVAVRAQQLAINGSTMLKKKYSSPIDIAKQELFNRKIPLLVMRCIKVTPDGQKIVEIWNPREMGIPLLD
What is the function of this protein?
Component of the DNA-directed RNA polymerase (RNAP) that catalyzes the transcription in the cytoplasm of viral DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit 6 homolog, RPB6 homolog.
What is the protein family that this protein belongs to?
Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Host cytoplasm. Virion. Note=Found in association with viral nucleoid.
Protein: HS7C2_DICDI
Sequence: MSSSIGIDLGTTYSCVGVWQNDRVEIIANDQGNRTTPSYVAFNETERLIGDAAKNQVAMNPTNTIFDAKRLIGRKFSDPVIQSDMKHWPFKVIAKEGDKPHLQVEFKGEVKTFSPEEVSSMVLLKMKETAEAYLGKTINNAVITVPAYFNDSQRQATKDAGAIAKLNVQRIINEPTAAAIAYGLEKKSQGERNILIFDLGGGTFDVSLLTIEDGVFEVKATAGDTHLGGEDFDNRLVNHFVDEFKRKHKKDLMTNQRALRRLRTACERAKRTLSSSAQASIEIDSLFEGIDFYTSITRARFEELCADLFRGCLDPVDKVLKDSKLDKKTIHEIVLVGGSTRIPKVQQLLQDHFNGKELNKSINPDEAVAYGAAVQAAILSNEGGAKVADILLLDVAPLSMGLETAGGVMTTLIPRNTTIPCKKNQTFSTYSDNQTGVLVQVYEGERAMTRDNNLLGKFELTNIPPAPRGVPQIEVTFDIDANGILNVSAEDKSTGNKHKITITNDKGRLTAEQIEKMVKDAEMFKAQDEAQREVVESKNKLENYAYTVRSTIKDDKIAAKLSKEDRKTVEEKSDEAINWLHANDSATKEEYEKAMKDLEAVCSPIISKVYGQQGGENPGNFSGAKTTEEDLD
What is the function of this protein?
May function in protein folding and assembly, and disassembly of protein complexes.
What are the official names of this protein?
Heat shock cognate 70 kDa protein 2, HSC70-2.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: COBQ_RHILO
Sequence: MARAIMLQGTGSDVGKTVLVAGLCRAAKKRGLKVRPFKPQNMSNNAAVADIPGDNNHGGGEIGRAQWLQAIACGVAPSVHMNPVLLKPQSDVGAQVIVQGKVFGEARARDYQALKGRLMDAVLDSWAKVGEGADLVIVEGAGSPAEINLRSRDIANMGFATRADVPVVLVGDIDRGGVIASVAGTHLILPEEDRRMIVGYLINKFRGDVSLFDDGLKAIEKFTGWRCFGVVPWLKAAARLPSEDSVVLERLASGEARALKVAVPVLGRIANFDDLDPLKAEPQVEVVFVPPGKPLPSDAGLVVIPGSKSTIGDLIRFRENGWDRDLATHRKRGGHVVGICGGFQMLGRRVRDPDGIEGSVTEAEGLGLLDIETMMEPEKTVRNVSARSVQFDLPLEGYEIHLGRTTGPDTMRPSAIINGVADGAISADGKVIGTYMHGLFGADAFRGKFLESLGIKGGGIDYRVEVERALDDVAAELEGHLDCDALFGLAR
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: FADI_ECOK1
Sequence: MGQVLPLVTRQGDRIAIVSGLRTPFARQATAFHGIPAVDLGKMVVGELLARTEIPAEVIEQLVFGQVVQMPEAPNIAREIVLGTGMNVHTDAYSVSRACATSFQAVANVAESLMAGTIRAGIAGGADSSSVLPIGVSKKLARVLVDVNKARTMSQRLKLFSRLRLRDLMPVPPAVAEYSTGLRMGDTAEQMAKTYGITREQQDALAHRSHQRAAQAWSEGKLKEEVMTAFIPPYKQPLVEDNNIRGNSSLADYAKLRPAFDRKHGTVTAANSTPLTDGAAAVILMTESRAKELGLVPLGYLRSYAFTAIDVWQDMLLGPAWSTPLALERAGLTMGDLTLIDMHEAFAAQTLANIQLLGSERFARDVLGRAHATGEVDESKFNVLGGSIAYGHPFAATGARMITQTLHELRRRGGGFGLVTACAAGGLGAAMVLEAE
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, ACSs, Acetyl-CoA acyltransferase, Acyl-CoA ligase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RFX3_MOUSE
Sequence: MQTSETGSDTGSTVTLQTSVASQAAVPTQVVQQVPVQQQVQQVQTVQQVQHVYPAQVQYVEGSDTVYTNGAIRTTTYPYTETQMYSQNTGGNYFDTQGSSAQVTTVVSSHSMVGTGGIQMGVTGGQLISSSGGTYLIGNSMENSGHSVTHTTRASPATIEMAIETLQKSDGLSTHRSSLLNSHLQWLLDNYETAEGVSLPRSTLYNHYLRHCQEHKLDPVNAASFGKLIRSIFMGLRTRRLGTRGNSKYHYYGIRVKPDSPLNRLQEDMQYMAMRQQPMQQKQRYKPMQKVDGVADGFTGSGQQTGTSVEQTVIAQSQHHQQFLDASRALPEFGEVEISSLPDGTTFEDIKSLQSLYREHCEAILDVVVNLQFSLIEKLWQTFWRYSPSTPADGTTITESSNLSEIESRLPKAKLITLCKHESILKWMCNCDHGMYQALVEILIPDVLRPIPSALTQAIRNFAKSLEGWLSNAMNNIPQRMIQTKVAAVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQASWVCQCDDNMVQRLETDFKMTLQQQSTLEQWAAWLDNVMMQALKPYEGRPSFPKAARQFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAQVTGETPIAVMGEFGDLNAVSPGNLDKDEGSEVESETDEDLDDSSEPRAKREKTELSQAFPVGCMQPVLESAVQPSLLNPLHSEHIVTSTQTIRQCSATGNTYTAV
What is the function of this protein?
Transcription factor required for ciliogenesis and islet cell differentiation during endocrine pancreas development.  Essential for the differentiation of nodal monocilia and left-right asymmetry specification during embryogenesis.  Required for the biogenesis of motile cilia by governing growth and beating efficiency of motile cells (PubMed:15121860, PubMed:19671664).  Also required for ciliated ependymal cell differentiation (PubMed:16930429).  Together with RFX6, participates in the differentiation of 4 of the 5 islet cell types during endocrine pancreas development, with the exception of pancreatic PP (polypeptide-producing) cells (PubMed:17229940).  Regulates transcription by forming a heterodimer with another RFX protein and binding to the X-box in the promoter of target genes (By similarity).  Regulates the expression of genes involved in ciliary assembly (DYNC2LI1, FOXJ1 and BBS4) and genes involved in ciliary motility (DNAH11, DNAH9 and DNAH5).  Represses transcription of MAP1A in non-neuronal cells but not in neuronal cells.
What are the official names of this protein?
Transcription factor RFX3, Regulatory factor X 3.
What is the protein family that this protein belongs to?
Belongs to the RFX family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RIMP_STRS2
Sequence: MFMSSIIELVTAAITPAIQTPYELVDVEYGKMGGDYVLSIFVDKEGGISLQDTADLSEKISPILDTIKPDPFPDQYMLEVTSPGLERPLKTADAVEKAVGKYIHVKLYQAIDKIKVFEGTLLSFDGTDLIMEYMDKTRKKEVTIPYQTVAKARLAVKL
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISDB_STAA9
Sequence: MNKQQKEFKSFYSIRKSSLGVASVAISTLLLLMSNGEAQAAAEETGGTNTEAQPKTEAVASPTTTSEKAPETKPVANAVSVSNKEVEAPTSETKEAKEVKEVKAPKETKAVKPAAKATNNTYPILNQELREAIKNPAIKDKDHSAPNSRPIDFEMKKENGEQQFYHYASSVKPARVIFTDSKPEIELGLQSGQFWRKFEVYEGDKKLPIKLVSYDTVKDYAYIRFSVSNGTKAVKIVSSTHFNNKEEKYDYTLMEFAQPIYNSADKFKTEEDYKAEKLLAPYKKAKTLERQVYELNKIQDKLPEKLKAEYKKKLEDTKKALDEQVKSAITEFQNVQPTNEKMTDLQDTKYVVYESVENNESMMDTFVKHPIKTGMLNGKKYMVMETTNDDYWKDFMVEGQRVRTISKDAKNNTRTIIFPYVEGKTLYDAIVKVHVKTIDYDGQYHVRIVDKEAFTKANTDKSNKKEQQDNSAKKEATPATPSKPTPSPVEKESQKQDSQKDDNKQLPSVEKENDASSESGKDKTPATKPTKGEVESSSTTPTKVVSTTQNVAKPTTASSKTTKDVVQTSAGSSEAKDSAPLQKANIKNTNDGHTQSQNNKNTQENKAKSLPQTGEESNKDMTLPLMALLALSSIVAFVLPRKRKN
What is the function of this protein?
Cell wall-anchored surface receptor that extracts heme from oxidized metHb to enable growth on hemoglobin as a sole iron source.  Rapidly extracts heme from hemoglobin and transfers it to IsdA or IsdC, which then relays it to the membrane transporter/IsdEF for internalization.  Promotes also resistance to hydrogen peroxide and killing by neutrophils.
What are the official names of this protein?
Iron-regulated surface determinant protein B, Fur-regulated protein B, Staphylococcal iron-regulated protein H, Staphylococcus aureus surface protein J.
What is the protein family that this protein belongs to?
Belongs to the IsdB family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor. Note=Anchored to the cell wall by sortase A.
Protein: PTXBC_STAAS
Sequence: MTKEQQLAERIIAAVGGMDNIDSVMNCMTRVRIKVLDENKVDDQELRHIDGVMGVIHDERIQVVVGPGTVNKVANHMAELSGVKLGDPIPHHHNDSEKMDYKSYAADKAKANKEAHKAKQKNGKLNKVLKSIANIFIPLIPAFIGAGLIGGIAAVLSNLMVAGYISGAWITQLITVFNVIKDGMLAYLAIFTGINAAKEFGATPGLGGVIGGTTLLTGIAGKNILMNVFTGEPLQPGQGGIIGVIFAVWILSIVEKRLHKIVPNAIDIIVTPTIALLIVGLLTIFIFMPLAGFVSDSLVSVVNGIISIGGVFSGFIIGASFLPLVMLGLHHIFTPIHIEMINQSGATYLLPIAAMAGAGQVGAALALWVRCKRNTTLRNTLKGALPVGFLGIGEPLIYGVTLPLGRPFLTACIGGGIGGAVIGGIGHIGAKAIGPSGVSLLPLISDNMYLGYIAGLLAAYAGGFVCTYLFGTTKAMRQTDLLGD
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  This system is involved in the uptake and phosphorylation of MurNAc-GlcNAc, the principle peptidoglycan turnover product of S. aureus, yielding cytoplasmic MurNAc 6P-GlcNAc.
What are the official names of this protein?
PTS system MurNAc-GlcNAc-specific EIIBC component.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SURE_XANCP
Sequence: MRVLVSNDDGVDAPGIQILAEALRRAGHEVMVVAPDRDRSGASNSLTLDVPIRTRRIDAQTCAVAGTPTDCVHLALTGMLDYDPDIVVSGINNSANLGDDVIYSGTVSAAMEGRFLGLPAVAVSLVTQNHEAHHFETAARAAVEIVARLKADPLPADTILNVNVPDLAWADVLGFEVTRLGNRHRSEPCVPQNDPRGRTVYWIGPAGPEQDAGAGTDFHAVRTGHISITPIHVDLTRYQALDTVAGWVGGLTAALDAPA
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KIF24_HUMAN
Sequence: MASWLYECLCEAELAQYYSHFTALGLQKIDELAKITMKDYSKLGVHDMNDRKRLFQLIKIIKIMQEEDKAVSIPERHLQTSSLRIKSQELRSGPRRQLNFDSPADNKDRNASNDGFEMCSLSDFSANEQKSTYLKVLEHMLPDDSQYHTKTGILNATAGDSYVQTEISTSLFSPNYLSAILGDCDIPIIQRISHVSGYNYGIPHSCIRQNTSEKQNPWTEMEKIRVCVRKRPLGMREVRRGEINIITVEDKETLLVHEKKEAVDLTQYILQHVFYFDEVFGEACTNQDVYMKTTHPLIQHIFNGGNATCFAYGQTGAGKTYTMIGTHENPGLYALAAKDIFRQLEVSQPRKHLFVWISFYEIYCGQLYDLLNRRKRLFAREDSKHMVQIVGLQELQVDSVELLLEVILKGSKERSTGATGVNADSSRSHAVIQIQIKDSAKRTFGRISFIDLAGSERAADARDSDRQTKMEGAEINQSLLALKECIRALDQEHTHTPFRQSKLTQVLKDSFIGNAKTCMIANISPSHVATEHTLNTLRYADRVKELKKGIKCCTSVTSRNRTSGNSSPKRIQSSPGALSEDKCSPKKVKLGFQQSLTVAAPGSTRGKVHPLTSHPPNIPFTSAPKVSGKRGGSRGSPSQEWVIHASPVKGTVRSGHVAKKKPEESAPLCSEKNRMGNKTVLGWESRASGPGEGLVRGKLSTKCKKVQTVQPVQKQLVSRVELSFGNAHHRAEYSQDSQRGTPARPASEAWTNIPPHQKEREEHLRFYHQQFQQPPLLQQKLKYQPLKRSLRQYRPPEGQLTNETPPLFHSYSENHDGAQVEELDDSDFSEDSFSHISSQRATKQRNTLENSEDSFFLHQTWGQGPEKQVAERQQSLFSSPRTGDKKDLTKSWVDSRDPINHRRAALDHSCSPSKGPVDWSRENSTSSGPSPRDSLAEKPYCSQVDFIYRQERGGGSSFDLRKDASQSEVSGENEGNLPSPEEDGFTISLSHVAVPGSPDQRDTVTTPLREVSADGPIQVTSTVKNGHAVPGEDPRGQLGTHAEYASGLMSPLTMSLLENPDNEGSPPSEQLVQDGATHSLVAESTGGPVVSHTVPSGDQEAALPVSSATRHLWLSSSPPDNKPGGDLPALSPSPIRQHPADKLPSREADLGEACQSRETVLFSHEHMGSEQYDADAEETGLDGSWGFPGKPFTTIHMGVPHSGPTLTPRTGSSDVADQLWAQERKHPTRLGWQEFGLSTDPIKLPCNSENVTWLKPRPISRCLARPSSPLVPSCSPKTAGTLRQPTLEQAQQVVIRAHQEQLDEMAELGFKEETLMSQLASNDFEDFVTQLDEIMVLKSKCIQSLRSQLQLYLTCHGPTAAPEGTVPS
What is the function of this protein?
Microtubule-dependent motor protein that acts as a negative regulator of ciliogenesis by mediating recruitment of CCP110 to mother centriole in cycling cells, leading to restrict nucleation of cilia at centrioles.  Mediates depolymerization of microtubules of centriolar origin, possibly to suppress aberrant cilia formation (PubMed:21620453).  Following activation by NEK2 involved in disassembly of primary cilium during G2/M phase but does not disassemble fully formed ciliary axonemes.  As cilium assembly and disassembly is proposed to coexist in a dynamic equilibrium may suppress nascent cilium assembly and, potentially, ciliar re-assembly in cells that have already disassembled their cilia ensuring the completion of cilium removal in the later stages of the cell cycle (PubMed:26290419).  Plays an important role in recruiting MPHOSPH9, a negative regulator of cilia formation to the distal end of mother centriole (PubMed:30375385).
What are the official names of this protein?
Kinesin-like protein KIF24.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Primarily localizes to the mother centriole/basal body and is either absent at daughter centriole.
Protein: ATPL_CAMJJ
Sequence: MKKVLFLLLACAAVAFAAETNAPVEQEAINVWIKAFSVLAAGLGLGVAALGGAIGMGNTAAATIAGTARNPGLGPKLMTTMFIALAMIEAQVIYALVIALIALYANPFIVLQ
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HDGR2_RAT
Sequence: MPHAFKPGDLVFAKMKGYPHWPARIDDIADGAVKPPPNKYPIFFFGTHETAFLGPKDLFPYDKCKDKYGKPNKRKGFNEGLWEIQNNPHASYSAPLPVSSSDSEAPEADLGGGSDADKEKEARRVMTVTAVTTTATSGRTESDSDSDKNSDHSGLKRKTPVLKMSVSKRARKASSDLDQASVSPSEEDSESPSESEKTSDQDFTPEKKTIARAPRRAPLGGRKKKKVPSASDSDSRADSDGAKEEPVVTAQPSPSSSSSSSSSSASDSDVSIKKPPRGRKPAEKPPPKPRGRRSKPERPPSTSSSDSDSDSGEVDRISEWKRRDEERRRELEARRRREQEEELRRLREQEREEKERRKERAERGGSSGEELEDEEPVKKRSRKARGRGTPSSSDSEPEGELGKEGKKLAKKSQLQGSESARKPGQKEKRGRPDEKPRARPVKVERTRKRSEGLSLDRKGEKKKEPSVEERLQKLHSEIKFALKVDNPDVRRCLSALEELGTLQVTSQILQKNTDVVATLKKIRRYKANKDVMAKAAEVYTRLKSRVLGPKVEALQKVNKAGAEKERADGEKVEEQPGEQAPRELAEDEPSTDRSAPVNGEAASQKGENTEDGAQEDGQDLEDGPRGGSSEELHDSPQDSSDPARPGNEHQDHERMQLASESADDDDEDS
What is the function of this protein?
Acts as an epigenetic regulator of myogenesis in cooperation with DPF3a (isoform 2 of DPF3/BAF45C) (By similarity).  Associates with the BAF complex via its interaction with DPF3a and HDGFL2-DPF3a activate myogenic genes by increasing chromatin accessibility through recruitment of SMARCA4/BRG1/BAF190A (ATPase subunit of the BAF complex) to myogenic gene promoters (By similarity).  Promotes the repair of DNA double-strand breaks (DSBs) through the homologous recombination pathway by facilitating the recruitment of the DNA endonuclease RBBP8 to the DSBs (By similarity).  Preferentially binds to chromatin regions marked by H3K9me3, H3K27me3 and H3K36me2 (By similarity).  Involved in cellular growth control, through the regulation of cyclin D1 expression (By similarity).
What are the official names of this protein?
Hepatoma-derived growth factor-related protein 2, HRP-2, Hepatoma-derived growth factor 3, HDGF-3.
What is the protein family that this protein belongs to?
Belongs to the HDGF family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: RL7_BORT9
Sequence: MALSKEDILTWLEEAKTSEVVELITAIEEKFGVTAAAVAVAAGSGPASVDAEEQTEFDVMLMSFGDSKINVIKEVRAVTGLGLGEAKALVEAAPKAIKEGVSKADAEDIKKKLEAVGAKVEIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: Y4722_BACC4
Sequence: MKVSYHGHSVVKIEANGKVILIDPFLTGNPKTDLKAEDVKVDAILLSHGHGDHVGDTVELAKKNNAVVVAPFELATFLSWQGVNTHPMHIGGSHEFDFGKVKLTQAFHGSSYIDEENKTITYTGMPAGILFTAEEKTVYHAGDTALFSDMKLIGELNKVDLAFLPIGDNFTMGPEDAVLAAKWINAKTVVPMHYNTFPVIEQDPYQFVEKLQNCTGKVLEAGESITL
What are the official names of this protein?
UPF0173 metal-dependent hydrolase BCB4264_A4722.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: PB1F2_I03A1
Sequence: MEQGQDTPWTQSTEHTNIQKRGSGQQTQRLEHPNSTRLMDHYLRIMSPVGMHKQIVYWKQWLSLKNPTQESLKTRVLKRWKLFNKQEWIN
What is the function of this protein?
Plays an important role in promoting lung pathology in both primary viral infection and secondary bacterial infection.  Promotes alteration of mitochondrial morphology, dissipation of mitochondrial membrane potential, and cell death.  Alternatively, inhibits the production of interferon in the infected cell at the level of host mitochondrial antiviral signaling MAVS.  Its level of expression differs greatly depending on which cell type is infected, in a manner that is independent of the levels of expression of other viral proteins.  Monocytic cells are more affected than epithelial cells.  Seems to disable virus-infected monocytes or other host innate immune cells.  During early stage of infection, predisposes the mitochondria to permeability transition through interaction with host SLC25A6/ANT3 and VDAC1.  These proteins participate in the formation of the permeability transition pore complex (PTPC) responsible of the release of mitochondrial products that triggers apoptosis.
What are the official names of this protein?
Protein PB1-F2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB1-F2 family.
What are the subcellular locations of this protein?
Host mitochondrion inner membrane. Host nucleus. Host cytoplasm, host cytosol. Note=Inner mitochondrial membrane in most cells types. Otherwise is detected in the nucleus and cytosol.
Protein: MNHA1_STAEQ
Sequence: MSLLHIAVLLPLIFALIIPFLYRFVKRIHLGWFVLPVPIVLFIYFISLISMTMSGNNVMKNLNWMPHIGMNFNLYVDGLGLLFSLLITGIGSLVVLYSIGYLSKSEQLGNFYCYLLLFMGAMLGVVLSDNFIILYLFWELTSFSSFLLISFWREKKASIYGAQKSLIITVLGGLSMLGGIILLSLATDTFSIQAMISKASDIQNSPFFILVMILFMIGAFTKSAQVPFYIWLPDAMEAPTPVSAYLHSATMVKAGLYLIARITPIFAISEGWVWTITLVGLITLFWASLNATKQHDLKGILAFSTVSQLGMIMSMLGIGAVSYHYQGANSQLYVAGFVAAIFHLINHATFKGALFMITGGIDHSTGTRDVKKLGGLLTIMPISFTLTVITTLSMAGVPPFNGFLSKEKFLESMINVTHLNLMSLNTLGILLPIIAIIGSIFTFVYSIKFILHIFFGSYKPEALPKQAHESSILMLISPIILTSLVIVFGLFPSILTQSIIEPASVAVSQTSNITAEFHLFHGITPAFLSTIGIYIIGILLLISFSYWVRLLQAHPYQLTLNHWYDTSGQRIPGYSENITNSYVTGFSRNNLVIILGILIALTFVTVISVPFSIDFKNVSHLRVFEGATVLFLLIASTFIIFAKSRLFSIIMLSAVGYAISVLFIFFKAPDLALTQFVVESISTALFLLCFYHLPNLNRYNEKPTFKLTNAVISIGVGLSVIILGLIGYGNRHFDSITKFYQEHVFDLAHGKNMVNVILVDFRGMDTLFESSVLGIAGLGVYTMIKLRLKQKNQSSEVNDHE
What is the function of this protein?
Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.
What are the official names of this protein?
Na(+)/H(+) antiporter subunit A1, Mnh complex subunit A1.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.