PharMolix/UniProtQA huggingface dataset:
Protein: BLI1_YEASV
Sequence: MGEQNKLYYDVEKLVNSLQESFDLDCAQSVSLFTSKSRSNEAWLEELENKFKLKDDVELDDVENLRAEIDMKLNMLEDKVSYYERLYKELEEFQNEIKIKTVVNNRRQSRTPK
What is the function of this protein?
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.
What are the official names of this protein?
Biogenesis of lysosome-related organelles complex 1 subunit BLI1, BLOC-1 subunit BLI1, BLOC-1 interactor 1.
What is the protein family that this protein belongs to?
Belongs to the BLI1 family.
What are the subcellular locations of this protein?
Endosome.
Protein: Y2166_ALISL
Sequence: MSKNDHLSDDELSLFREAVQGSKKLRQDTIIHQPSKNFSEQQKQRKSLKEGKNEEFFFSDEFVPLLNEDGPVRYARDGVSKYEVKRLRRGVYVPDVFLDMHGMKQDEAKRELGSMIAYCLKENISCASVMHGIGKHILKQKVPLWLAQHPDVMAFHQAPLEFGGAGAILVLLSIPDR
What are the official names of this protein?
UPF0115 protein VSAL_I2166.
What is the protein family that this protein belongs to?
Belongs to the UPF0115 family.
Protein: BOP1_BRUMA
Sequence: MIHKRMNSTELERTSKKIDDYDSSDEEDLRNTIGNIPISWYDDFSHVGYDKDGNQIESAKKNDDMEEFLDRMDDSNYWRRVYDRQSGGFVTLNDEEVKKLNALDASKYPLVGYNPYQPFLDIFSSQTEIHPISNRPDSKRSFIPSLDEKRLVGKMVHAIKMGWVRPSRPKQIEKRVYDLWADNPCSEKTKTELARIRMHFPAPKVPLPGHAESYNPPAEYLCDEEELKKWEETDPEDRRLDFIPKKYDCLRKVPAYDRFYNDRYQRCLDLYLAPRQRKMKLNIDHTELLPELPNLTDMRPFPTTQSFLMLGHSGQVRSLSFEPESTEIFASGGEDGTLRLWSICDGRCLKTTSLDGSITSVAYCPLAKWTLLAVTMESNKMILTNSYCGDRHRITTTTEYLSKLRCESSESDVLKWKYEGKGTLSVDLGYIARQVVWHHKGDYFATFANSKSPKLIYIHQLSKCKSQRPFSRLKGLMTVLSFHPSEPFLFVGTQRYIRIYDLAKCQLKKKIITGSQWMSCMHVDFRGDNVFVGGHDRVFSWIDLQLSSKPWKSVKHHTAAIRGVTQHARCPLIATVSDDSTAIVYYARISSDSLKENEFVPVRRLRTQTAQKNGLSILAAIFHPSQPWLITAHVDGSIALFT
What is the function of this protein?
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
What are the official names of this protein?
Ribosome biogenesis protein BOP1 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat BOP1/ERB1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: Y7305_AFIC5
Sequence: MAGHSQFKNIMHRKGKQDAMRSKVFGKLAREITVAAKLGTPDPAMNPRLRAAVLAARAENMPKDNIERAIKKAAGGDSENYDEIRYEGYGPGGVAVIVEALTDNRNRAASDIRSYFTKSGGNLGETGSVSFMFDRVGVIEYDADKASADDMLEAAIEAGADDVASSEEGHEIYTSQASLSEAAKALEAKFGEPRKAALIWKPQNNIAVSDEVGEKLFKLLDQLNEHDDVQNVYANFEVSDTLAAKMAG
What are the official names of this protein?
Probable transcriptional regulatory protein OCAR_7305/OCA5_c08120.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPB_BEII9
Sequence: MSELKLVVAGAAGRMGRVLIQTAIETSGVTVSAALARPGSLALGQDAGLLAGCGEINVPITEDALAAIVDADGILDFTSPDLSVELAALAAQARIVHIIGTTGFSVAHLTKIEAAARHAVIVRSGNMSLGVNLLAALVKKTAAVLGPVYDIEIAEMHHRMKVDAPSGTALLLGEAAAQGRGISLSEHEQRGRDGHTGPRKDGDIGFVSLRGGTVVGDHTVIFAGPGERIELAHRAEDRRIFGRGAVQAALWGKGRKPGLYSMLDVLGLGGE
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNO1_CAEBR
Sequence: MATSSSAFDDEFPMEEGMPELLDDEDVPSTLPSLLEQNMDTALKSNEFKLVKRKRRAGNAVDVVMEDISQPDDSTTDSPDADAEQKPTKRSKGSKGESRVVPVPKHRYTPLKDNWVNIFTPIVKNLGLQIRFNLKKRQVELRNPADREDTTDLQKATDFVRAFILGFEVNDAIALIRLDHLFLETFEIADVKHSLKGDHVSRAIGRIAGKDGRTKLVIENTTKTRIVVANTKIHILGAYQNLKLARNAVCSLILGSNPSKVYGNLRNMASRGAERL
What is the function of this protein?
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.  Positively regulates dimethylation of two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA.
What are the official names of this protein?
RNA-binding protein pno-1.
What is the protein family that this protein belongs to?
Belongs to the PNO1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: UMPS_HUMAN
Sequence: MAVARAALGPLVTGLYDVQAFKFGDFVLKSGLSSPIYIDLRGIVSRPRLLSQVADILFQTAQNAGISFDTVCGVPYTALPLATVICSTNQIPMLIRRKETKDYGTKRLVEGTINPGETCLIIEDVVTSGSSVLETVEVLQKEGLKVTDAIVLLDREQGGKDKLQAHGIRLHSVCTLSKMLEILEQQKKVDAETVGRVKRFIQENVFVAANHNGSPLSIKEAPKELSFGARAELPRIHPVASKLLRLMQKKETNLCLSADVSLARELLQLADALGPSICMLKTHVDILNDFTLDVMKELITLAKCHEFLIFEDRKFADIGNTVKKQYEGGIFKIASWADLVNAHVVPGSGVVKGLQEVGLPLHRGCLLIAEMSSTGSLATGDYTRAAVRMAEEHSEFVVGFISGSRVSMKPEFLHLTPGVQLEAGGDNLGQQYNSPQEVIGKRGSDIIIVGRGIISAADRLEAAEMYRKAAWEAYLSRLGV
What is the function of this protein?
Bifunctional enzyme catalyzing the last two steps of de novo pyrimidine biosynthesis, orotate phosphoribosyltransferase (OPRT), which converts orotate to orotidine-5'-monophosphate (OMP), and orotidine-5'-monophosphate decarboxylase (ODC), the terminal enzymatic reaction that decarboxylates OMP to uridine monophosphate (UMP).
What are the official names of this protein?
Uridine 5'-monophosphate synthase, UMP synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the OMP decarboxylase family.
Protein: MUTL_DEIRA
Sequence: MPTPIHVLPPHVARLIAAGEVVSRPLDVVRELVENALDAGASRIEIEVDGGGLERVQVRDNGSGIAAQSVPLAPARHATSKLTAGPETGSLSVTTLGFRGEALWAAAQAGELELTTRPAAQVGAARLRAQGDAVEVSRTSAPAGTTVTVSQLFARLPARLRTQASAAAEVRDITALLGRYVLHHSALHWRLTVDGDPRLTHAPADHRGAVATVYGPLSANRVLTLDTPGVRGVVSRPELTRARRDRMHFAVNGRPIVAPPELERAVIDAYAELLPAGTAPLCVLDLTVAPEDYDPNIHPAKQVVALADLPAVALRVRDAVAGALAGHPLVRAAPALIAPPEPHPAPTAGNFPDLTLLGVYQELYLLAQGEGDLWVVDAHAAHERALYERLGRELGTAAPLELPTPELLHLTPEQTARLHERGAELRGWGLTIEDFGAGLARLRTLPAALAALPVPRLHEVVVETALSGGPDPRREVLARLACLPALKAGMLDAERGALVLAALRECEQPWACPHGRPTVLRLSERDLAHAFGRRGVRDVARGRDSVV
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: Y3516_CYTH3
Sequence: MGRAYELRKGRRAKRFDRMAKAFTRLGKEIVMAAKQGGGNIETNSRLRTAVNNAKSVNMPKDRIDAAIKRASGKDESDYEEVVFEGYGPYGIAILVECATDNNTRTVANVRSYFTRSGGALGKTGSLEFLFERKGVIKIDGTGLDPEELELELIDFGAEEIVKDGNEIFIYTAFVDFGTMLKELEQRNITVINAETERIPNTTTTLTTEQQEEIYKLLEKFEDDDDVQAVFHNMAETE
What are the official names of this protein?
Probable transcriptional regulatory protein CHU_3516.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FIB12_BPT4
Sequence: MSNNTYQHVSNESRYVKFDPTDTNFPPEITDVQAAIAAISPAGVNGVPDASSTTKGILFIPTEQEVIDGTNNTKAVTPATLATRLSYPNATETVYGLTRYSTNDEAIAGVNNESSITPAKFTVALNNAFETRVSTESSNGVIKISSLPQALAGADDTTAMTPLKTQQLAIKLIAQIAPSETTATESDQGVVQLATVAQVRQGTLREGYAISPYTFMNSSSTEEYKGVIKLGTQSEVNSNNASVAVTGATLNGRGSTTSMRGVVKLTTTAGSQSGGDASSALAWNADVIQQRGGQIIYGTLRIEDTFTIANGGANITGTVRMTGGYIQGNRIVTQNEIDRTIPVGAIMMWAADSLPSDAWRFCHGGTVSASDCPLYASRIGTRYGGNPSNPGLPDMRGLFVRGSGRGSHLTNPNVNGNDQFGKPRLGVGCTGGYVGEVQIQQMSYHKHAGGFGEHDDLGAFGNTRRSNFVGTRKGLDWDNRSYFTNDGYEIDPESQRNSKYTLNRPELIGNETRPWNISLNYIIKVKE
What is the function of this protein?
Structural component of the short tail fiber.  Adhesion protein that binds irreversibly to the lipopolysaccharides component (LPS) on the cell surface of Escherichia coli B strains during virus attachment.  After at least three long tail fibers have bound, short tail fibers extend and bind irreversibly to the core region of the host cell LPS.
What are the official names of this protein?
Short tail fiber protein gp12, Gene product 12, gp12.
What is the protein family that this protein belongs to?
Belongs to the tevenvirinae short tail fiber protein family.
What are the subcellular locations of this protein?
Virion.
Protein: DNLJ_RHOMR
Sequence: METHTAPQTAEARLLEATHTLLQTVRQRDLEAIDRKEAEALAARLREVLNQHAYRYYVLDNPLIPDADYDLLMQALRKLEARFPELVTPDSPTQRVGGPPLGRFEKVRHPEPLLSLNNAFGEEDVRVWYERCCRMLAERLGQPVQPAVTAELKIDGLAMALTYENGVLSVGATRGDGIEGENVTQNVRTIPAIPLRIPVDPAVGPPPTRLEVRGEVYMRKRDFERLNEQLQARGERPFANPRNAAAGSVRQLNPQVTALRPLSFFAYGIGPVEGAEVPDSQYEVLQWLGRLGFPVNEHARRFEHLDDVLEYCRYWTEHRDELDYEIDGVVLKIDHRPWQALLGAISNAPRWAVAYKFPAREAITRLLDIMVSVGRTGVVKPVAVLEPVEVGGVTVSQATLHNEDYVRSRDIRIGDLVVVIRAGDVIPQVVRPVVEARTGNERPWRMPERCPSCGSQLVRLPGEADYYCVASDCPAQFVRLLEHFAGRDAMDIEGMGSQVARQLAESGLVRPLSDLYRLKLEDLLKLEGFAETRARNLLRAIEASKQRPLSRLLFGLGIRHVGKTTAELLVQRFASIDELAAATIDELAALEGVGPITAESIANWFRVEDNRRLIEELKELGVNTQRLPEEAPAAESPVRGKTFVLTGALPHLTRKEAEELIKRAGGRVASSVSRNTDYVVVGENPGSKYDRARQLGIPMLDEDGLLRLLGMK
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: CYSO_MYCTU
Sequence: MNVTVSIPTILRPHTGGQKSVSASGDTLGAVISDLEANYSGISERLMDPSSPGKLHRFVNIYVNDEDVRFSGGLATAIADGDSVTILPAVAGG
What is the function of this protein?
In its thiocarboxylated form (CysO-COSH), is the sulfur donor in the CysM-dependent cysteine biosynthetic pathway.  May be of particular importance for cysteine biosynthesis in the persistent phase of M. tuberculosis.
What are the official names of this protein?
Sulfur carrier protein CysO, 9.5 kDa culture filtrate antigen cfp10A.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein CysO family.
Protein: EZRA_STRS7
Sequence: MSSGIILLIVAIVLLVIIAYLVGVIIRKRNDTLITSLEERKQALFGLPVNDEIEEVKSLHLIGQSQTSFREWNQKWVDLTLNTFTDIEKHIFEAEHLNDTFNFIRAKHEINSVESQLNLVEEDITAIREALGILKEQEEKNSARVTHALDLYEKLQASVAENEDNFGSTMAEIEKQMKNIEAEFSQFVALNSSGDPVEAAEVLDKAEEHTIALGQITEQIPAIVAKLEDDFPDQLDDLETGYRRLLEENYHFPEKNIEARFQEIRESIRANSSELVTLDLDRARDENTHIQERIDSLYELFEREIAAYKVVAKNSKILPRYLAHAKHNNEQLKHEIARLSRKYILSENEGLNIKAFDKDLKDIEDNVLEIAEAFDQQEKPFSELQLILDRSIKTLASVESGQMDVFAAVKDIEKIESQARQHLEIYVTQLHMIKRYMEKRNLPGIPQDFLSTFFTTSSQLEALMDELSRGRINIEAVSRLSEVATAAIANLEELTYQVVQHATLTEQLLQYSNRYRSFEAGVQNSFEHALKLFEVDNDYQASFDEISYALETVEPGVTERFVNSYEKTRERIRF
What is the function of this protein?
Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation.  Inhibits FtsZ ring formation at polar sites.  Interacts either with FtsZ or with one of its binding partners to promote depolymerization.
What are the official names of this protein?
Septation ring formation regulator EzrA.
What is the protein family that this protein belongs to?
Belongs to the EzrA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=Colocalized with FtsZ to the nascent septal site.
Protein: PXPA_STAS1
Sequence: MKVDLNCDLGEAFGNYSFGGDNQIIPLITSANIACGFHAGDQHVMNDTIKLAKDNGIGIGAHPGLPDLQGFGRRNMDLSPEEVYDIVVYQLGALNGFCRIHDVKINHVKPHGALYQMGARDKVIAHAIAKAVYDFDPTLIYVGLSNTLLISEAQALGLSTASEVFADRRYEDDGQLVSRKEADALITNTDEAIKQVINMVKFQKVITKNNNTIDIKADTICVHGDGAHAIEFVTQIREQLTKEGISITRLGG
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: ABNC_ASPCL
Sequence: MFVYTLIFLFLAAANAYSNPGPCSGNCWTHDPGLYQRKSDGKYFLFATGGGIHISSADDLAGPWTDDGFVLPDGSSIDLDGQNNLWAPDLHYRDGTYYLYYSVSALGSQNSAIGVATSETLEAGSWTDHGSTGVTSTPNSPYNTIDGNWIAVGDKQYLNFGSYWQNLFQVELADGLKVKEGATPHQLSYNASGIHRQEAAFMFERNSYFYLTFSGGVALGYNATWPAQGEEYHINVCRSTSATGGFVDKNGVSCLNSGGSLLLASHGFVYGPGGQGILEDRNKELVLYYHYADTRIGKAVEDYQFGWNQLKWENDWPSV
What is the function of this protein?
Endo-1,5-alpha-L-arabinanase involved in degradation of pectin.  Its preferred substrate is linear 1,5-alpha-L-arabinan (By similarity).
What are the official names of this protein?
Probable arabinan endo-1,5-alpha-L-arabinosidase C, Endo-1,5-alpha-L-arabinanase C, ABN C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 43 family.
What are the subcellular locations of this protein?
Secreted.
Protein: TXVE1_SISCA
Sequence: MAAYLLAVAILFCIQGWPSGTVQGQAMPFMEVFERSVCQTREMLVSILDEHPDEVAHLFRPSCVTVLRCGGCCTDESLMCTATGKRSVGREIMRVDPRKETSKIQVMQFTEHTKCECRPRSGRVNSGKRKRNPEEGGAESQVPLGLTSF
What is the function of this protein?
Snake venom VEGFs that may contribute to venom dispersion and prey subjugation by inducing vascular permeability and hypotension.  This protein induces an increase in capillary permeability after intradermal injection, as well as a drastic hypotensive effect after intravenous injection (By similarity).  The hypotension is mediated by nitric oxide (NO), which is produced by VEGF-activated endothelium NO synthase.  Also induces angiogenesis in vitro (By similarity).  Like other crotalid VEGFs, this protein interacts with VEGF receptor-1 (FLT1) with a high affinity, whereas it binds to VEGF receptor-2 (KDR) with a low affinity (By similarity).
What are the official names of this protein?
Snake venom vascular endothelial growth factor toxin 1, svVEGF, VEGF-F.
What is the protein family that this protein belongs to?
Belongs to the PDGF/VEGF growth factor family. Snake venom VEGF subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TDH_SALPA
Sequence: MKALSKLKAEEGIWMTDVPEPEVGHNDLLIKIRKTAICGTDVHIYNWDDWSQKTIPVPMVVGHEYVGEVVGIGQEVKGFKIGDRVSGEGHITCGHCRNCRGGRTHLCRNTTGVGVNRPGCFAEYLVIPAFNAFKIPDNISDDLASIFDPFGNAVHTALSFDLVGEDVLVSGAGPIGVMAAAVAKHVGARHVVITDVNEYRLELARKMGVTRAVNVAKESLNDVMAELGMTEGFDVGLEMSGAPPAFRTMLDTMNHGGRIAMLGIPPSDMSIDWTKVIFKGLFIKGIYGREMFETWYKMAALIQSGLDLSPIITHRFSIDDFQKGFDAMRSGQSGKVILSWD
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_SALPB
Sequence: MASENMTPQEYIGHHLNNLQLDLRTFSLVDPQNPPATFWTLNIDSMFFSVVLGLLFLVMFRSVAKKATSGVPGKFQTAIELIVGFVHGSVKDMYHGKSKLIAPLALTIFVWVFLMNLMDLLPIDLLPYIAEHWLGLPATRVVPSADVNITLSMALGVFILILFYSIKMKGIGGFAKELTLQPFNHWAFIPVNLILEGVSLLSKPVSLGLRLFGNMYAGELIFILIAGLLPWWSQWILNVPWAIFHILIITLQAFIFMVLTIVYLSMASEEH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PDIA6_DROME
Sequence: MRQLASILLLAFVVGSVSAFYSPSDGVVELTPSNFDREVLKDDAIWVVEFYAPWCGHCQSLVPEYKKLAKALKGVVKVGSVNADADSTLSGQFGVRGFPTIKIFGANKKSPTDYNGQRTAKAIAEAALAEVKKKVQGVLGGGGGSSSGGSGSSSGDDVIELTEDNFDKLVLNSDDIWLVEFFAPWCGHCKNLAPEWAKAAKELKGKVKLGALDATAHQSKAAEYNVRGYPTIKFFPAGSKRASDAQEYDGGRTASDIVSWASDKHVANVPAPELIEIINESTFETACEGKPLCVVSVLPHILDCDAKCRNKFLDTLRTLGEKFKQKQWGWAWAEGGQQLALEESLEVGGFGYPAMAVVNFKKMKFSVLKGSFSKDGINEFLRDISYGRGHTAPVRGAKKPAIVSVDPWDGKDGQLPTEEDIDLSDIDLDKDEL
What is the function of this protein?
Binds to both apoptotic cells and phagocytes and promotes Drpr-dependent phagocytosis of apoptotic cells.
What are the official names of this protein?
Protein disulfide-isomerase A6 homolog, Calcium-binding protein 1, DmCaBP1.
What is the protein family that this protein belongs to?
Belongs to the protein disulfide isomerase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen. Cell surface. Note=Relocates from the endoplasmic reticulum to the cell surface during apoptosis.
Protein: RNZ_MARN8
Sequence: MEFTFLGTSAGTPTRSRNVTGLALCLSGPKPWYLVDCGEGTQHQLMRTRYSVMQLRAMFITHIHGDHIFGLPGLLTSASMLGRTEPLDIIAPPQVRRFIDAVIENSDSSLSYPLNFINSEAPDFYWQDDHLGVTNVALSHRVPCRAYVFTERNLERQLQKEKLVADGIEPGPQWGDLQKGKDVLLDDGRLLRSNDYTHIPRTARKIIVGGDNDTPELLKDACQGTHVLIHEATYTQDVADRVGPWPQHSSAQQVARFAQATKLPNLVLTHFSSRYQSAPGGSPHINQLAAEALQHYKGQLFLARDFDTYRLEKDFQLHKVDHN
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: ZAPA_BACAN
Sequence: MSQQKGKKSRINVEIYGQQYSVVGDESTSHIRMVAAIVDDKMRELNAKNPSLDTSRLAVLTAVNVIHDYIKLKEEHEKLKESMTKKGME
What is the function of this protein?
Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring.  It is recruited early at mid-cell but it is not essential for cell division.
What are the official names of this protein?
Cell division protein ZapA, Z ring-associated protein ZapA.
What is the protein family that this protein belongs to?
Belongs to the ZapA family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes at mid-cell. In sporulating cells, localizes near the cell poles.
Protein: GLNE_ECOLI
Sequence: MKPLSSPLQQYWQTVVERLPEPLAEESLSAQAKSVLTFSDFVQDSVIAHPEWLTELESQPPQADEWQHYAAWLQEALCNVSDEAGLMRELRLFRRRIMVRIAWAQTLALVTEESILQQLSYLAETLIVAARDWLYDACCREWGTPCNAQGEAQPLLILGMGKLGGGELNFSSDIDLIFAWPEHGCTQGGRRELDNAQFFTRMGQRLIKVLDQPTQDGFVYRVDMRLRPFGESGPLVLSFAALEDYYQEQGRDWERYAMVKARIMGDSEGVYANELRAMLRPFVFRRYIDFSVIQSLRNMKGMIAREVRRRGLTDNIKLGAGGIREIEFIVQVFQLIRGGREPSLQSRSLLPTLSAIAELHLLSENDAEQLRVAYLFLRRLENLLQSINDEQTQTLPSDELNRARLAWAMDFADWPQLTGALTAHMTNVRRVFNELIGDDESETQEESLSEQWRELWQDALQEDDTTPVLAHLSEDDRKQVLTLIADFRKELDKRTIGPRGRQVLDHLMPHLLSDVCAREDAAVTLSRITALLVGIVTRTTYLELLSEFPAALKHLISLCAASPMIASQLARYPLLLDELLDPNTLYQPTATDAYRDELRQYLLRVPEDDEEQQLEALRQFKQAQLLRIAAADIAGTLPVMKVSDHLTWLAEAMIDAVVQQAWVQMVARYGKPNHLNEREGRGFAVVGYGKLGGWELGYSSDLDLIFLHDCPMDAMTDGEREIDGRQFYLRLAQRIMHLFSTRTSSGILYEVDARLRPSGAAGMLVTSAEAFADYQKNEAWTWEHQALVRARVVYGDPQLTAHFDAVRREIMTLPREGKTLQTEVREMREKMRAHLGNKHRDRFDIKADEGGITDIEFITQYLVLRYAHEKPKLTRWSDNVRILELLAQNDIMEEQEAMALTRAYTTLRDELHHLALQELPGHVSEDCFTAERELVRASWQKWLVEE
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia (PubMed:8412694).  When cellular nitrogen levels are high, the C-terminal adenylyl transferase inactivates GlnA by covalent transfer of an adenylyl group from ATP to 'Tyr-398' of GlnA, thus reducing its activity (PubMed:4920894, PubMed:9312015).  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity (PubMed:4893578, PubMed:4920873, PubMed:4934180, PubMed:9312015, PubMed:14766310).  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell (PubMed:8412694).
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.
Protein: GATC_BORPA
Sequence: MALNEQDVARIARLALIELPPDQRGRAQAELNGILHLIERLQAVDTQGVEPLAHPLSAHEDITLRLREDAVSEQATEARRAELLANAPESADGLFLVPKVIE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: YL647_MIMIV
Sequence: MYKMPFDRAGCLNNVGGFGSCGSNYNRINDAKLLKRELHFTETLLDTINRECASGFNNYGYGGGNCGFNDCGFGGCGPAPCGPGGFGGGFGGGFGGGFGGPFNGGAGVEVEGWGYGPQPFQGGFGGGYFDKDDDKKKKKKDDKKDDPCNPFCKPCYKPVCNNPKEKVCKCKECKRASRKIYEDY
What are the official names of this protein?
Uncharacterized protein L647.
What are the subcellular locations of this protein?
Virion.
Protein: MURC_SYNC1
Sequence: MYGKIRTIHFVGIGGIGMSGIAEVLLNLGYRVSGSDLRVSEITQRLCDLGGMIAYGHAAENLGDADVVVTSTAVKSDNPEVIEAHRRLIPVIPRAEMLAELMRMKYGIAVAGTHGKTTTTSMVSTVLSKSGIDPTVVIGGRLDSIGSNAKLGQGKFLVAEADESDGSFLKLSPIIAVVTNVDADHLDYYSDLDEIKRTFVDFINKIPFYGVAILCLDDPNVQALIPQVGKRFVTYGMSTQADYNAQEISYQEERTTFTVCWQGERLGQLSIRMPGQHNVLNALAAVAVARELEIPFEQIAEAFCDFCGVQRRFQPKYQGRDIMVVDDYGHHPAEIKVTLAAACSGWNRRVVAVFQPHRYSRTQALFDEFVTAFYQADHLVVMDIYAAGETPIPGVEARLLAEGIAGHGHRDVHYCPDAEAVAAHLREVVQAGDLVLTLGAGNVWQIGEALAEWLQQRD
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S39A9_CHICK
Sequence: MDDFRSICLLSLAMLVACYVAGIIPLAVNFSEERLKLVTVLGAGLLCGTALAVIVPEGVHALYEDILEGKHHPANEMQHVMESEKVAEIAVVHEYGHDHSRLHAYIGVSLVLGFVFMLLVDQIGSSHVHSTDDPEAARSGNSKITTTLGLVVHAAADGVALGAAASTSQTSVQLIVFVAIMLHKAPAAFGLVSFLMHAGLERNRIRKHLLVFALAAPVMSMVTYLGLSKSSKEALSEVNATGVAMLFSAGTFLYVATVHVLPEVGGIAHSHRPESTGGKGLSRLEVAALVLGCLIPLVLSIGHHH
What is the function of this protein?
Transports zinc ions across cell and organelle membranes into the cytoplasm and regulates intracellular zinc homeostasis.  Participates in the zinc ions efflux out of the secretory compartments (By similarity).  Regulates intracellular zinc level, resulting in the enhancement of AKT1 and MAPK3/MAPK1 (Erk1/2) phosphorylation in response to the BCR activation (PubMed:23505453).  Also functions as membrane androgen receptor that mediates, through a G protein, the non-classical androgen signaling pathway, characterized by the activation of MAPK3/MAPK1 (Erk1/2) and transcription factors CREB1 or ATF1 (By similarity).  Moreover, has dual functions as membrane-bound androgen receptor and as an androgen-dependent zinc transporter both of which are mediated through an inhibitory G protein (Gi) that mediates both MAP kinase and zinc signaling leading to the androgen-dependent apoptotic process (By similarity).
What are the official names of this protein?
Zinc transporter ZIP9, Solute carrier family 39 member 9, Zrt- and Irt-like protein 9, ZIP-9.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.