PharMolix/UniProtQA huggingface dataset:
Protein: RPPH_BRUSI
Sequence: MSKHKGPTGAMVDPESLPYRPCVGLMVLNKAGLVWAGRRIVIPGDEMDGATQLWQMPQGGIDKGEDPAQAALRELYEETGMTSVSLLEEASDWINYDLPPHLVGLALKGKYRGQTQKWFAYRFEGDESEIAINPPPGGHTAEFDCWEWKPMADLPNLIVPFKRKVYEQVVATFRHLAA
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: RL36_MYCTO
Sequence: MKVNPSVKPICDKCRLIRRHGRVMVICSDPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36, Ribosomal protein B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: PURA_THESM
Sequence: MPSYIVVGGQWGDEGKGSIIAYLAIHDKPEVIARGGVGTNAGHSVFINGKKYAVRQLPTGFMNENARLLVGAGVLVDPEVFFHELEHLKDFNVRGRIGLDYRCTVIEPGHKELDRSNGYLHGKIGTTGSGCGPANADRALRKAKQVKDLKELEPYLTDVAQEVNEALDEGKLVLVEGTQGFGLSLYYGSYPYVTSKDTSASAIASDVGIGPTRVDDVIVVFKSFPTRVGAGPFPTEMSEEEAERMGLVEYGTVTGRRRRVGWFDFEFARYSARINGATMLAVTMLDKYDKEAFGVTDFNKLPQKAKDFIAEIEEKVGVPVALIKTGPELEHIIDLRENI
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INGR1_CARAU
Sequence: MRTQIYISVTVLILLLKKSDLEAVRVPSPESVSVQCDSYGVEARWEYPEVHQDVYFQVKVKDEFTERDSSRTKNLHLNISSMLFRPAYNRYCVTVTAVRGGEKSDPSDFFIFSFNENAAAYIKCSLDFPEVELSPKDGRLHVQFTNPLHLYRNSPALRDLSEDLKYCIETDQGKNKVCETCQMKQNASCETSVVFSEHRGEYCFSLTGNIGQRIFNPRSSCFTGDIRRYTPFTVYLYPVLGVTLTLLFITGIIILLEKKCNSEMKKKVPSMFPHFFDFGETQSHLPKTLCVVADKVEPHLQIELVEDPEEQTSLVPLSDNKDLEGVYSEDKNSYGPNDLVEDEQSDLSDFYDCPHAPKQKREMSPGDTVDSYGPRLL
What is the function of this protein?
Receptor which shows binding specificity for the cytokine ifng1r (interferon gamma-related).
What are the official names of this protein?
Interferon gamma receptor 1, Interferon gamma receptor 1-1.
What is the protein family that this protein belongs to?
Belongs to the type II cytokine receptor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RS17_WOLWR
Sequence: MPKKVFCGTVTKAKCDKTVKVSVLQVYKDELYKKVIKKYKKYTAHDENNSCKEGDKVLIQEHKPISTTKKWVIVNSSH
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: ASF1_COCIM
Sequence: MSVVSLLGVRVLNNPAAFTAPYEFEITFECLEQLQKDLEWKLTYVGSATSSEYDQELDSLLVGPIPVGVNKFIFEADPPDLKRIPTSEILGVTVILLTCSYDGREFVRVGYYVNNEYDSEELNKEPPTKPIIERVRRNVLAEKPRVTRFHIKWDTDSDPTEFPPVQPDADVLEDDGETYGAEELELEAALKRELEELDSQDADKMDVGEGRDDVDDNESDAGSEDLEGETSGSDDEEEEEGFEGEDEDVEMGDDSNPTPDQHQHPNPEVMVH
What is the function of this protein?
Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.
What are the official names of this protein?
Histone chaperone ASF1, Anti-silencing function protein 1.
What is the protein family that this protein belongs to?
Belongs to the ASF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CHOX_ARTGO
Sequence: MHIDNIENLSDREFDYIVVGGGSAGAAVAARLSEDPAVSVALVEAGPDDRGVPEVLQLDRWMELLESGYDWDYPIEPQENGNSFMRHARAKVMGGCSSHNSCIAFWAPREDLDEWEAKYGATGWNAEAAWPLYKRLETNEDAGPDAPHHGDSGPVHLMNVPPKDPTGVALLDACEQAGIPRAKFNTGTTVVNGANFFQINRRADGTRSSSSVSYIHPIVEQENFTLLTGLRARQLVFDADRRCTGVDIVDSAFGHTHRLTARNEVVLSTGAIDTPKLLMLSGIGPAAHLAEHGIEVLVDSPGVGEHLQDHPEGVVQFEAKQPMVAESTQWWEIGIFTPTEDGLDRPDLMMHYGSVPFDMNTLRHGYPTTENGFSLTPNVTHARSRGTVRLRSRDFRDKPMVDPRYFTDPEGHDMRVMVAGIRKAREIAAQPAMAEWTGRELSPGVEAQTDEELQDYIRKTHNTVYHPVGTVRMGAVEDEMSPLDPELRVKGVTGLRVADASVMPEHVTVNPNITVMMIGERCADLIRSARAGETTTADAELSAALA
What is the function of this protein?
Catalyzes the two-step oxidative conversion of choline to glycine-betaine with betaine aldehyde as an intermediate.  Glycine-betaine accumulates to high levels in the cytoplasm of cells to prevent dehydration and plasmolysis in adverse hyperosmotic environments.  Accepts either choline or the reaction intermediate betaine-aldehyde as substrate.
What are the official names of this protein?
Choline oxidase.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: AMPP1_LEPMJ
Sequence: MAKVDTTERLAELRKLMKERNVDIYMVPSEDSHQSEYIAPCDARRGSAGYAVITHDKAALATDGRYFNQAEKQLDGNWELLKQGIQDVPTIQDWTADQVEGGKVVAVDPSVVTAADARKLADKIKKKGGEYKAVDDNLVDKIWSDRPSRPHEKVIVQPIEFSGKSFEDKIEDLRKELEKKKSLGFVVSMLDEIAWLFNLRGSDIPYNPVFFSYAVVTPTTVTLYVDDHKLPEEVKKHLGDKVTIRPYNAIFEELTTLSKEAFTKDKADATSKFLTSSRASWALNKALGGEDRVEETRSPVGDAKAVKNEVELEGMRQCHLRDGAALSEYFAWLEDQLINKKAELDEVDGADKLEAIRKKHDKFMGLSFDTISSTGANAAVIHYKPEKGECAVIDAKAIYLCDSGAQYRDGTTDTTRTVHFTEPTEMEKKAYTLVLKGNMALERVKFPKGTTGFALDSLARQFLWAEGLDYRHGTGHGVGSFLNVHEGPIGIGTRVQYSEVSLAVGNVVSDEPGYYEDGKFGIRIENMIMVKEVETSHKFGDKPYLGFEHVTMTPHCRNLVDMSLLGEDEKQFINDYHKEVYEKTSGYFEDDALTLKWLKRETAPY
What is the function of this protein?
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.
What are the official names of this protein?
Probable Xaa-Pro aminopeptidase P, AMPP, Aminopeptidase P, Aminoacylproline aminopeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: AIM6_LACTC
Sequence: MKYLSYTITFVKNTHRSCQRINKSASFGMIGSLAIGFVLMIVSFWAGTYVNVRGNPVMLDFSDGASSTRGDSNAHNNLGLTGANLLHFFKNRMSDTKDLTDARGVQVSRFYDEVVRYLTAENAGASTAEGTCFPEGSIVSKLTRNVNVVPKVHSHNDYWRDLPLFEALCHGIPSVEADVWLVDNDTQLAVGHNEAFLDHAHRTLHSLYTGPLLTMLNEVNCNLGDKDHKYGVFYSSPETTLNLYIDFKSPDSTQTYALLMDLYLKPLIDMGYLTYFDMDEEKVVWNPVTVILTGDYPTDPTVLDGQEQKGYYNTTQRFVFLDAPMHKLDEHYSGISVVASASLQQLLGNCKDLSQEADRSLLRQGSLPTESVTCVAKQVQKAQSLGLKTRIWGAPTWPESSKQKLWSQQIFDIGIDFLNTDDLEEVTHL
What are the official names of this protein?
Altered inheritance of mitochondria protein 6.
What is the protein family that this protein belongs to?
Belongs to the AIM6 family.
Protein: CPFC_STRPS
Sequence: MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYDNYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCICLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQDSFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPWIKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMPNTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVKKLIEKKGRENVKMPYLIKKMLEKAGKLPKE
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
What are the official names of this protein?
Coproporphyrin III ferrochelatase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAL11_YEAST
Sequence: MKNIISLVSKKKAASKNEDKNISESSRDIVNQQEVFNTEDFEEGKKDSAFELDHLEFTTNSAQLGDSDEDNENVINEMNATDDANEANSEEKSMTLKQALLKYPKAALWSILVSTTLVMEGYDTALLSALYALPVFQRKFGTLNGEGSYEITSQWQIGLNMCVLCGEMIGLQITTYMVEFMGNRYTMITALGLLTAYIFILYYCKSLAMIAVGQILSAIPWGCFQSLAVTYASEVCPLALRYYMTSYSNICWLFGQIFASGIMKNSQENLGNSDLGYKLPFALQWIWPAPLMIGIFFAPESPWWLVRKDRVAEARKSLSRILSGKGAEKDIQVDLTLKQIELTIEKERLLASKSGSFFNCFKGVNGRRTRLACLTWVAQNSSGAVLLGYSTYFFERAGMATDKAFTFSLIQYCLGLAGTLCSWVISGRVGRWTILTYGLAFQMVCLFIIGGMGFGSGSSASNGAGGLLLALSFFYNAGIGAVVYCIVAEIPSAELRTKTIVLARICYNLMAVINAILTPYMLNVSDWNWGAKTGLYWGGFTAVTLAWVIIDLPETTGRTFSEINELFNQGVPARKFASTVVDPFGKGKTQHDSLADESISQSSSIKQRELNAADKC
What is the function of this protein?
High-affinity uptake of alpha-glucosides such as maltose, turanose, isomaltose, alpha-methylglucoside, maltotriose, palatinose, trehalose, melezitose and glucose.  Acts with the concomitant transport of protons into the cell (symport system).
What are the official names of this protein?
General alpha-glucoside permease, Maltose permease MAL11, Maltose transport protein MAL11.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: 3MGH_DEIRA
Sequence: MRLARELLGGTLVRVTPDGHRLSGRVVEVEAYDCPRDPACTAGRFHAARSAEMAIAPGHWLFWFAHGHPLLQVACRQEGVSASVLIRALEPLEGAGKMLDYRPVTRQRDLTSGPAKLVYALGLDPMQISHRPVNSPELHLLAPETPLADDEVTVTARVGIREGRNLPWRFLIRGNGWVSPAQPSMELAAP
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: PDXJ_THEVB
Sequence: MATLGVNIDHVATIRQARRTVEPDPVAAALLAELGGADGITVHLREDRRHIQERDVRLLRQTVRTHLNLEMAATPEMVAIALDIRPDYVTLVPERREEVTTEGGLDVVSQQEPLTQVVQTLQGAGIPVSLFIDADPTQLAAAAKTTAQFIELHTGRYAEAKGEVAQQRELAILADGVQQAKALGLRVNAGHGLTYSNVGAIARLEGIEELNIGHTIISRAVLVGMVQAVRDMKALISP
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2024_YERPS
Sequence: MKHNLNAHEARVIGCLLEKQVTTPEQYPMSLNGLTLACNQKTSRDPVMELSESQVQQTLDFLLKKHLIRSQSGNRVMKYEHRFCNSEFGDLKFSPAEVAVITLLLLRGAQTPGELRTRTNRMYEFADVAETEETLKTLSLREDGPFVVRLAREPGKRESRFMPLFSGDVASSLLAAGEAEENNHTLEANPRETHSFENIALEKTALEARVAQLEQQVIQLSRRLDDVLIQLDD
What are the official names of this protein?
UPF0502 protein YPTB2024.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: NDB4A_ISOMC
Sequence: FIGMIPGLIGGLISAIK
What is the function of this protein?
Probably forms pores in target membranes.  Has antibacterial activity against Gram-positive bacteria S. aureus NBRC 13276 (MIC=5-10 uM) and B. subtilis NBRC 3009 (MIC=2. 5-5 uM) but not against Gram-negative bacterium E. coli NBRC 3972.
What are the official names of this protein?
Peptide Im-4.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Short antimicrobial peptide (group 4) family.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Probably forms a helical membrane channel in the prey.
Protein: IDHG1_MOUSE
Sequence: MALKVAIAAGGAAKAMLKPTLLCRPWEVLAAHVAPRRSISSQQTIPPSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAAHYPQITFDSMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSQAIQDIIRHIRIINGRAVEA
What is the function of this protein?
Regulatory subunit which plays a role in the allosteric regulation of the enzyme catalyzing the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate.  The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers.
What are the official names of this protein?
Isocitrate dehydrogenase [NAD] subunit gamma 1, mitochondrial, Isocitric dehydrogenase subunit gamma, NAD(+)-specific ICDH subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: COAD_MYCGI
Sequence: MSGAVCPGSFDPVTLGHIDVFERAAAQFDEIVVAVMVNPNKSGMFTLDERIALIEESTTHLPNLRVESGQGLIVDFVRERGLTAIVKGLRTGTDFEYELQMAQMNKHVAGIDTFFVATAPSYSFVSSSLAKEVAMLGGDVTALLPAAVNTRLTAKLAERG
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBX7_RAT
Sequence: MKLRVRLQKRTQPLEVPESEPTLGQLRAHLIQDLLPTLGFSSDTRFAITLNNKDALTGDEETLASYGIVSGDLICLVLEDEMPAPNLPSSTDSEHSSLQNNDQPPLAATSSQANIPDEQGSDSSHGQVTQYDAWTDDSMEGPSHSAEAVSIQDAMSVEEASGFHPLEPMLCSETEDGQVPHSLEALYQSAGCSTVSDALIVLVHLLMLESGYIPQGTEAKAASMPEKWKSSGVYKLQYTHPLCEGGSAVLTCVPLGKLIMINATIKVNGGIKNVKSVQLKPGAYVRRAEPGESAAKVYKDLKKLSRLFKDQLVYPLLAFTRQVLNLPDVFGLVVLPLELKLRIFRLLDVHSVLALSAVCHDLLIASNDPLLWRCLYLRDFRDSTIRGPDTDWKELYRKKHIQRKEAQRMRHVMYLPSVHPIPFCPIPVYPRPYLPTTLLPPGIIGGEYDERPILPSVGDPVTSLIPRPGEPPSQFRPVRPRFDPVGPLPGSNSLLPGRASPNNRFPFRPGRGRSADNRLPYL
What is the function of this protein?
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins and plays a role in several biological processes such as cell cycle, cell proliferation, or maintenance of chromosome stability.  Recognizes and ubiquitinates BIRC2 and the cell cycle regulator DLGAP5.  Plays a role downstream of PINK1 in the clearance of damaged mitochondria via selective autophagy (mitophagy) by targeting PRKN to dysfunctional depolarized mitochondria.  Promotes MFN1 ubiquitination.  Mediates the ubiquitination and proteasomal degradation of UXT isoform 2, thereby impairing the NF-kappa-B signaling pathway.  Inhibits NF-kappa-B pathway also by promoting the ubiquitinatioin of TRAF2 (By similarity).  Affects the assembly state and activity of the proteasome in the cells including neurons by ubiquitinating the proteasomal subunit PSMA2 via 'Lys-63'-linked polyubiquitin chains (By similarity).  Promotes 'Lys-48'-linked polyubiquitination SIRT7, leading to the hydrogen peroxide-induced cell death (By similarity).
What are the official names of this protein?
F-box only protein 7.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion. Cytoplasm, cytosol. Note=Predominantly cytoplasmic. A minor proportion is detected in the nucleus. Relocates from the cytosol to depolarized mitochondria (By similarity).
Protein: FBK15_ARATH
Sequence: MFEGRPRDSCLVSTLFTMPSHKETKWSFLVSGKRSFLNNDESDLHFKKMYKLTTDSSEGEDNGSSSDSGTLIPGMNRDDSLSCLIRCSRADYCSIASVNRSLRSLIRSGEIYRLRRLQGTLEHWVYFSCHLNEWEAFDPRSKRWMHLPSMPQNECFRYADKESLAVGTDLLVFGWEVSSYVIYRYSLLTNSWSTAKSMNMPRCLFGSASYGEIAVLAGGCDSSGRILDTAELYNYEDQTWLVLPGMNKRRKMCSGVFMDGKFYVIGGIGVGEENEPKVLTCGEEFDLKTRKWTEIPEMSPPRSNQGNGMSAAAMAPPLVAVVNDQLYAADHAGMAVRRYDKEKRVWNKVGNLPEQAGSMNGWGLAFRACGDRIIVIGGPKAPGEGFIELNSWVPSVTTPEWHLLGKKQSVNFVYNCAVMSC
What are the official names of this protein?
F-box/kelch-repeat protein At1g26930.
Protein: ITIH2_MOUSE
Sequence: MQRPVCLLIWLFLLEAQAFEIPINGNSEFAEYSDLVELAPDKLPFVQENGRHQRSLPEESGEETDTVDPVTLYSYKVQSTITSRVATTTIQSKLVNNSPLPQSVVFDVQIPKGAFISNFTMTVNGMTFTSSIKEKTVGRALYSQARAKGKTAGWVRSRTLDMENFNTEVNIPPGAKVQFELHYQEVKWRKLGSYEHKIHLQPGKLAKHLEVNVWIIEPQGMRFLHVPDTFEGHFQGVPVISKGQQKAHVSFKPTVAQQRKCPNCTETAVNGELVVMYDVNREEKAGELEVFNGYFVHFFAPENLDPIPKNILFVIDVSGSMWGIKMKQTVEAMKTILDDLRTDDQFSVVDFNHNVRTWRNDLVSATKTQIADAKRYIEKIQPSGGTNINEALLRAIFILNEASNMGLLNPDSVSLIILVSDGDPTVGELKLSKIQKNVKQSIQDNISLFSLGIGFDVDYDFLKRLSNENRGIAQRIYGNQDTSSQLKKFYNQVSTPLLRNVQFNYPQASVTDVTQNNFHNYFGGSEIVVAGKFDPSKLTEVQSIITATSANTELVLETLSQMDDLEEFLSKDKHADPDFTKKLWAYLTINQLLAERSLAPTAAIKRKITKTILQMSLDHHIVTPLTAMVIENDAGDERMLADSPPQDHSCCSGALYYGTKVASGPIPSWANPSPTPMSAMLAVGAKPLESTPPTHLNQVENDPHFIIYLPKSKRNICFNIDSEPGKILSLVSDPESGIVVNGQLIGAKRAENGKLSTYFGKLGFYFQKEGMKIEISTETITLSSGSSTSRLSWSDTAHLGNSRVLISVKKEKSVTLTLNKELFFSVLLHRVWRKHPVNVDFLGIYAPPIDKFSPRVHGLLGQFMQEPAIHIFNERPGKEPGKPEASMEVKGHKLTVTRGLQKDYRTDIVFGTDVPCWFVHNSGKGFIDGHYKDYFVPQLYSFLKRP
What is the function of this protein?
May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.
What are the official names of this protein?
Inter-alpha-trypsin inhibitor heavy chain H2, ITI heavy chain H2, ITI-HC2, Inter-alpha-inhibitor heavy chain 2.
What is the protein family that this protein belongs to?
Belongs to the ITIH family.
What are the subcellular locations of this protein?
Secreted.
Protein: RLMB_XANAC
Sequence: MSKQNQWIVGVNAVASSVENDADNVREVLIEAGSKNPRLTEIEEQARRKGIDVRRVNTQALDGVGGQVRHQGVAARYAAARLWAENELEGLVEAAAGRALVLILDGVQDPHNLGACLRSAAAAGVTAVVIPKDKSATVNATVRKTSAGAADRIPVVAVTNLARCLRDLQKQGVWLYGLAGEAEASLYSVDLRGNVGLVLGGEADGLRRLTREHCDGLVKIPMPGEIESLNVSVATGVTLFEAVRQRLGA
What is the function of this protein?
Specifically methylates the ribose of guanosine 2251 in 23S rRNA.
What are the official names of this protein?
23S rRNA (guanosine-2'-O-)-methyltransferase RlmB, 23S rRNA (guanosine2251 2'-O)-methyltransferase, 23S rRNA Gm2251 2'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SHO1_ZYGRC
Sequence: MVMDKVPMPSRAKAKAQRKKLHINHSFSLNNLFSDPFALSSISITLLSWCIAIAGCIATASDTDNFPRFTWWGIAYQFLILFMVIIFYCYDMVDYYKNFIAGATAVSFVYNTNSATILVYGDGSRKAAASAGVILLSIVNLIWIFYYGSDNASPTSRWIDSFSLRGIRPSATQDASMRARRRNRNNLRSQRFTGDNFYPEHQPQNYMSSMALTGFENPDPAYYTGPNVPLDRNGSVAYSDNNMPGAFTQDMNANNQNNLNPNNFNQNNSNQNTFNQNTFMTETSNGNTDTTMGGTLELYSDAGEESFPYTAQTLYRYQADEDDAYEISFEQGEILKVSDIEGRWWKAKRSTGETGIIPSNYVKLIEDNIAM
What is the function of this protein?
Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.
What are the official names of this protein?
High osmolarity signaling protein SHO1, Osmosensor SHO1.
What is the protein family that this protein belongs to?
Belongs to the SHO1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y816_STAA3
Sequence: MADESKFEQAKGNVKETVGNVTDNKNLENEGKEDKASGKAKEFVENAKEKATDFIDKVKGNKGE
What are the official names of this protein?
UPF0337 protein SAUSA300_0816.
What is the protein family that this protein belongs to?
Belongs to the UPF0337 (CsbD) family.
Protein: ZAPB_SALA4
Sequence: MSLEVFEKLEAKVQQAIDTITLLQMEIEELKEKNNSLTQEVQSAQHQREELERENNSLKEQQSGWQERLQALLGRMEEV
What is the function of this protein?
Non-essential, abundant cell division factor that is required for proper Z-ring formation.  It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle.  Its recruitment to the Z-ring requires functional FtsA or ZipA.
What are the official names of this protein?
Cell division protein ZapB.
What is the protein family that this protein belongs to?
Belongs to the ZapB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the septum at mid-cell, in a FtsZ-like pattern.
Protein: LPXD2_LEGPL
Sequence: MSNYQFTKPAGPFYLAELAEISGSTLYEGKGEAFTVSGLAKLSEATTHNLVMLHQKKYLKELKNTAARACIIGPEYVKFAPDSMYLLVHPNPYKAFALIAQAFYPSEKPAGFIASSAAIETSAVIGSNCYIAHGVYIGNNAKIGSGCQIGVNTYIGDGVTIGDDCLIEDNVSIRHAVIGKHVVIYPGARIGQDGFGFASDASGHYKIPHAGGVIIGNHVEIGANTCIDRGSLDNTVIEDWCRLDNLVQVGHNVKIGKGSIIVAQVGIAGSTELGEYVTLAGQAGVIGHLKIGKGATVLASGKVYKNVKSGDRVGGHPAVSISDWQKQIRFLKTAIKPKKSPKS
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: DNAK_NITHX
Sequence: MGKVIGIDLGTTNSCVAVMDGKTPKVIENAEGMRTTPSIVAFSDDGERLVGQPAKRQAVTNPERTIFAVKRLIGRRYDDPTVEKDKHLVPYKIAKAGNGDAWVEVDGKTYSPSQISAFTLQKMKETAEAHLGQKVDQAVITVPAYFNDAQRQATKDAGKIAGLEVLRIINEPTAAALAYGLDKAKQGTIAVYDLGGGTFDVSILEIGDGVFEVKSTNGDTFLGGEDFDMRLVSYLADEFQKEQGINLRNDKLALQRLKEAAEKAKIELSSTTQTEINLPFITADQSGPKHLTMKLTRAKFEALVDDLVQKTIEPCRKALKDAGLTAGEIGEVVLVGGMTRMPKVQEVVKQLFGKEPHKGVNPDEVVAIGAAIQAGVLQGDVKDVLLLDVTPLSLGIETLGGVFTRIIDRNTTIPTKKSQVFSTAEDSQNAVTIRVFQGEREMAADNKILGQFDLMGIPPAPRGMPQIEVTFDIDANGIVNVSAKDKATGKEQQIRIQASGGLSEADIDKMVKDAEANAIEDKKRREAVDAKNHADSLVHSTEKALAEHGSKIEDSERRAIEDAVSDLKEALKGDDAEAIKAKTNTLAQASMKLGEAMYKQQAEADAAKDAAKDDVVDAEFTEVDDDKNKKSA
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RS21_PSEF5
Sequence: MPAVKVKENEPFDVALRRFKRSCEKAGVLAEVRSREFYEKPTSERKRKAAAAVKRHAKKVQREQRRAVRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: CLPP5_ARATH
Sequence: MAHACVSTSASSLRFTAGFVSASPNGSSFDSPKLSLPFEPLRSRKTNKLVSDRKNWKNSTPKAVYSGNLWTPEIPSPQGVWSIRDDLQVPSSPYFPAYAQGQGPPPMVQERFQSIISQLFQYRIIRCGGAVDDDMANIIVAQLLYLDAVDPTKDIVMYVNSPGGSVTAGMAIFDTMRHIRPDVSTVCVGLAASMGAFLLSAGTKGKRYSLPNSRIMIHQPLGGAQGGQTDIDIQANEMLHHKANLNGYLAYHTGQSLEKINQDTDRDFFMSAKEAKEYGLIDGVIMNPLKALQPLAAA
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins (By similarity).
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 5, chloroplastic, Endopeptidase ClpP5, nClpP5, nClpP1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
Protein: CATC_PSEAE
Sequence: MLFHVKMTVKLPVDMDPQQAERLKAEEKEMAQRLQREGSWRHLWRIAGHYANYSLFDLPSVEALHDTLTRLPLFPYMDIEIDGLCRHPSSIHADDR
What are the official names of this protein?
Muconolactone Delta-isomerase, MIase.
What is the protein family that this protein belongs to?
Belongs to the muconolactone Delta-isomerase family.
Protein: UNG_HHV2H
Sequence: MFSASTTPEQPLGLSGDATPPLPTSVPLDWAAFRRAFLIDDAWRPLLEPELANPLTARLLAEYDRRCQTEEVLPPREDVFSWTRYCTPDDVRVVIIGQDPYHHPGQAHGLAFSVRADVPVPPSLRNVLAAVKNCYPDARMSGRGCLEKWARDGVLLLNTTLTVKRGAAASHSKLGWDRFVGGVVQRLAARRPGLVFMLWGAHAQNAIRPDPRQHYVLKFSHPSPLSKVPFGTCQHFLAANRYLETRDIMPIDWSV
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or deamination of cytosines.  Therefore may reduce deleterious uracil incorporation into the viral genome, particularly in terminally differentiated cells which lack DNA repair enzymes.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG, UNG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: Y326_THEP3
Sequence: MITREMIDRINFLYHKSQTEGLTEEEKEEQKRLRQEYVKEIKERVRRELESIKYANNSCEHCGHDHHHHHHHHRH
What are the official names of this protein?
UPF0291 protein Teth39_0326.
What is the protein family that this protein belongs to?
Belongs to the UPF0291 family.
What are the subcellular locations of this protein?
Cytoplasm.