PharMolix/UniProtQA huggingface dataset:
Protein: TUSA_SALTY
Sequence: MSDLFSSPDHTLDALGLRCPEPVMMVRKTVRNMQTGETLLIIADDPATTRDIPGFCTFMEHDLLAQETEGLPYRYLLRKAH
What is the function of this protein?
Sulfur carrier protein involved in sulfur trafficking in the cell.  Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA.  Interacts with IscS and stimulates its cysteine desulfurase activity.  Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation.  Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.
What are the official names of this protein?
Sulfur carrier protein TusA, Sulfur mediator TusA, Sulfur transfer protein TusA, tRNA 2-thiouridine synthesizing protein A.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENDO2_ARATH
Sequence: MANQKGLHVVMMIITVWLLYAAPNIHGWGKEGHEIICKIAQTRLDETAAKAVKELLPESAEGDLSSLCLWADRVKFRYHWSSPLHYINTPDACSYQYNRDCKDESGEKGRCVAGAIYNYTTQLLSYKTAASSQSQYNLTEALLFVSHFMGDIHQPLHVSYASDKGGNTIEVHWYTRKANLHHIWDSNIIETAEADLYNSALEGMVDALKKNITTEWADQVKRWETCTKKTACPDIYASEGIQAACDWAYKGVTEGDTLEDEYFYSRLPIVYQRLAQGGVRLAATLNRIFG
What is the function of this protein?
Endonuclease mostly active on RNA and ssDNA, and to a lower extent, on dsDNA (PubMed:22506810, PubMed:23620482).  Can cleave mismatch regions in heteroduplex DNA containing single base pair mismatches or insertion/deletion bases (PubMed:22506810).  In contradiction with PubMed:22506810, cannot hydrolyze single-stranded DNA and does not cleave mismatches (PubMed:17651368).
What are the official names of this protein?
Endonuclease 2, AtENDO2, Deoxyribonuclease ENDO2, Single-stranded-nucleate endonuclease ENDO2.
What is the protein family that this protein belongs to?
Belongs to the nuclease type I family.
Protein: CYB_TRATE
Sequence: MAPNIRKSHPLLKMINNSLIDLPAPSNISAWWNFGSLLAMCLATQILTGLLLAMHYTADTTLAFSSVAHTCRNVQYGWLIRNLHANGASFFFICIFLHIGRGLYYGSYLYKETWNTGVILLLTLMATAFVGYVLPWGQMSFGGATVITNLFSAIPYIGQALVEWAWGGFSVDNPTLTRFFALHFLLPFVIAGITIIHLIFLHESGSNNPLGISSNSDKIPFHPYYSLKDILGLTLMLTPLLTLALFSPNLLGDPENFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASVLILLLIPFLHKSKQRTMTFRPLSQTLFWLLVANLLVLTWVGSQPVEHPFIIIGQMASFSYFTILLILFPMTSTLENKMFNH
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RM49_CAEEL
Sequence: MLGSSLRIFSPRAVSRLSFSTTSVEKAEKLWENPWKHALPEKSRSLATVEEAPIDWSYVERLMPIEVVPNVPEHEKYPTPSGWTPPTEAAKTHQYYIRRRHDHLLPLYLERKRDLLNEKTLDFDYVELVTIRNVDGDIFACENDLRSYLEEHLGHSIASHVDELKGRIKIKGAPRVLIEQFFYSKGF
What are the official names of this protein?
Probable 39S ribosomal protein L49, mitochondrial, L49mt, MRP-L49.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mL49 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NIFK_CLOPA
Sequence: MLDATPKEIVERKALRINPAKTCQPVGAMYAALGIHNCLPHSHGSQGCCSYHRTVLSRHFKEPAMASTSSFTEGASVFGGGSNIKTAVKNIFSLYNPDIIAVHTTCLSETLGDDLPTYISQMEDAGSIPEGKLVIHTNTPSYVGSHVTGFANMVQGIVNYLSENTGAKNGKINVIPGFVGPADMREIKRLFEAMDIPYIMFPDTSGVLDGPTTGEYKMYPEGGTKIEDLKDTGNSDLTLSLGSYASDLGAKTLEKKCKVPFKTLRTPIGVSATDEFIMALSEATGKEVPASIEEERGQLIDLMIDAQQYLQGKKVALLGDPDEIIALSKFIIELGAIPKYVVTGTPGMKFQKEIDAMLAEAGIEGSKVKVEGDFFDVHQWIKNEGVDLLISNTYGKFIAREENIPFVRFGFPIMDRYGHYYNPKVGYKGAIRLVEEITNVILDKIERECTEEDFEVVR
What is the function of this protein?
This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.
What are the official names of this protein?
Nitrogenase molybdenum-iron protein beta chain, Dinitrogenase, Nitrogenase component I.
What is the protein family that this protein belongs to?
Belongs to the NifD/NifK/NifE/NifN family.
Protein: FAP_CHLRE
Sequence: MMLGPKTVTRGATKGAAPRSMAARRVGGARRLSVRAAAGPAGSEKFDYVLVGGGTASCVLANKLSADGNKKVLVLEAGPTGDAMEVAVPAGITRLFAHPVMDWGMSSLTQKQLVAREIYLARGRMLGGSSGSNATLYHRGSAADYDAWGLEGWSSKDVLDWFVKAECYADGPKPYHGTGGSMNTEQPRYENVLHDEFFKAAAATGLPANPDFNDWSHPQDGFGEFQVSQKKGQRADTYRTYLKPAMARGNLKVVIGARATKVNIEKGSSGARTTGVEYAMQQFGDRFTAELAPGGEVLMCSGAVHTPHLLMLSGVGPAATLKEHGIDVVSDLSGVGQNLQDHPAAVLAARAKPEFEKLSVTSEVYDDKCNIKLGAVAQYLFQRRGPLATTGCDHGAFVRTSSSLSQPDLQMRFVPGCALDPDGVKSYIVFGELKKQGRAWPGGITLQLLAIRAKSKGSIGLKAADPFINPAININYFSDPADLATLVNAVKMARKIAAQEPLKKYLQEETFPGERASSDKDLEEYIRRTVHSGNALVGTAAMGASPAAGAVVSSADLKVFGVEGLRVVDASVLPRIPGGQTGAATVMVAERAAALLRGQATIAPSRQPVAV
What is the function of this protein?
Catalyzes the decarboxylation of free fatty acids to n-alkanes or n-alkenes in response to blue light (PubMed:28860382, PubMed:30144559).  Substrate preference is toward fatty acids with C17 or C18 chains (PubMed:28860382, PubMed:30144559).  Saturated fatty acids are converted to alkanes, not alkenes (PubMed:28860382, PubMed:30144559).  The decarboxylation is initiated through electron abstraction from the fatty acid by the photo-excited FAD (By similarity).
What are the official names of this protein?
Fatty acid photodecarboxylase, chloroplastic, CrFAP.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YQGF_RICAE
Sequence: MIIKNLQEFYRLLIPNAPLIAIDYGSKKLGIALSNQELSIAMPLNTITEINKKIVITSLLNIIEKYKVCGVIIGLPIDMSGAVTEQTNIVMKFAEELAKSINLPIYLQDERLTTKAANNLLKSFGVKRKDRNNNDDAVAASMILETVLDSIKNI
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAST2_PROEX
Sequence: INWKAIIEAAKQAL
What is the function of this protein?
Mast cell degranulating peptide.  Activates G proteins (Gi component), which in turn activates the cascade of molecular events cAMP-regulated, resulting in mast cell degranulation.
What are the official names of this protein?
Mastoparan-2, Mastoparan II, MP-II.
What is the protein family that this protein belongs to?
Belongs to the MCD family. Mastoparan subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CINAL_PELPD
Sequence: MRISTLSIGDELIRGRIVDGNAATIAAALIGQGMRVQRHLTVGDSEPDIMDALADLGRTSDAIIVTGGLGPTVDDLTTHAVARATGRRLVVNEEAREHLHRMMARFGVPPGVQIGEKQAMIPTKTTLIPNPTGTACGFHLMHNGCYQFFMPGVPSEMTVMLHESVIPFLAERDTKRRSIRSLDLNVFGLGEPRVDELLAGIVLPGCGLQLGLCVSFPMIRVTLLAEADSVQGAEEILSRAADAARERLGEHVFSEENQNLAEAAGTLLLRQGMTLALAESCTGGMIAQQITSVAGCSGYFLEGAVTYGNVAKSRRLGVAAELIDGKGAVSSEVAEAMAKGIRASAGSDLGLAVTGIAGPDGGTEEKPVGTVYISLATADGCRTERFLFGRGRDDIRILTTWTALDWIRRYLLQRSAV
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: GLGB1_STRAW
Sequence: MIPRPPSDDRANQNGDGSKKTGAKKTGAKKAAAAKKTAGKKATPAAKATAAKGAVTKKTGKGKATAKKAVADKAAAKATVPQQAVPKQAVSKRAVSKKAVPRKAVVKAALDIPEAPVSPAVAPDDRDRLLSGTHHAPHSVLGAHPVPGGVAFRVLRPYALSVTVVTDDLRTELHDDGAGFFTGLLPLRAVPDYRLHVAYEGTVHETEDAYRFLPALGELDLHLINEGRHEELWTALGAEPMTHQGVPGTRFTVWAPNARGVRLAGTFNFWDATAFPLRSLGSSGVWELFVPGVGEGELYKFEITRPDGSKTLRADPVARRTEAPPRTSSIVHASHYAWADEAWMAARGERPVHESPFSVYEVHLPSWRPGLTYRQLAEQLPAYVADLGFTHVELLPVAEHPFGGSWGYQVTGFYAPTARLGTPDDFKYLVDALHRAGVGVLMDWVPAHFPRDDWALAEFDGRPLYEHEDPLRAAHPDWGTLEFDYGRREVRNFLVANAVYWCEEFHIDGLRVDAVASMLYLDYSREEGQWSPNEFGGRENLDAVAFLQEMNATVYRRVPGVVTIAEESTAWEGVTRATHDNGLGFGLKWNMGWMHDSLGYVQHEPVHRRFHHHEMTFSMVYAYSENYVLPISHDEVVHGKGSLVSKMPGDWWQQRATERAYLGFMWAHPGKQLLFMGQEFAQGAEWSETHGPDWWLLDPAYGAEPDHRGMRDLVRDLNTVYRHEPALWERDTDPSGFAWVTGDAVEDNVFAFLRHAADGTPLLAVSNFSPVVRHDYRLGVPDDIPAWHETLNTDGARYGGSDVTNPHPVKPEPQGRHGRPASIRLTLPPLSTLWLRPA
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB 1, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase 1, Alpha-(1->4)-glucan branching enzyme 1, Glycogen branching enzyme 1, BE 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: DDRGK_HUMAN
Sequence: MVAPVWYLVAAALLVGFILFLTRSRGRAASAGQEPLHNEELAGAGRVAQPGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQSFLTEFINYIKQSKVVLLEDLASQVGLRTQDTINRIQDLLAEGTITGVIDDRGKFIYITPEELAAVANFIRQRGRVSIAELAQASNSLIAWGRESPAQAPA
What is the function of this protein?
Substrate adapter for ufmylation, the covalent attachment of the ubiquitin-like modifier UFM1 to substrate proteins, which plays a key role in reticulophagy (also called ER-phagy) (PubMed:32160526).  In response to endoplasmic reticulum stress, promotes recruitment of the E3 UFM1-protein ligase UFL1 to the endoplasmic reticulum membrane: in turn, UFL1 mediates ufmylation of proteins such as RPN1 and RPL26/uL24, promoting reticulophagy of endoplasmic reticulum sheets (PubMed:32160526).  Ufmylation-dependent reticulophagy inhibits the unfolded protein response (UPR) by regulating ERN1/IRE1-alpha stability (PubMed:28128204, PubMed:32160526).  Ufmylation in response to endoplasmic reticulum stress is essential for processes such as hematopoiesis or inflammatory response (By similarity).  Required for TRIP4 ufmylation, thereby regulating nuclear receptors-mediated.  transcription (PubMed:25219498).  May play a role in NF-kappa-B-mediated transcription through regulation of the phosphorylation and the degradation of NFKBIA, the inhibitor of NF-kappa-B (PubMed:23675531).  Plays a role in cartilage development through SOX9, inhibiting the ubiquitin-mediated proteasomal degradation of this transcriptional regulator (PubMed:28263186).
What are the official names of this protein?
DDRGK domain-containing protein 1, Dashurin, UFM1-binding and PCI domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the DDRGK1 family.
Protein: PCP2_HUMAN
Sequence: MMDQEEKTEEGSGPCAEAGSPDQEGFFNLLSHVQGDRMEGQRCSLQAGPGQTTKSQSDPTPEMDSLMDMLASTQGRRMDDQRVTVSSLPGFQPVGSKDGAQKRAGTLSPQPLLTPQDPTALGFRRNSSPQPPTQAP
What is the function of this protein?
May function as a cell-type specific modulator for G protein-mediated cell signaling.
What are the official names of this protein?
Purkinje cell protein 2 homolog.
Protein: CLPS_CROS8
Sequence: MSKDKSWLDFDHLAEDDLREALKPPSMYKVILMNDDYTPMEFVIDVLQKFFSYDVERATQLMLTVHYQGKAICGVFTAEVAETKVALVNKYARENDHPLLCTLEKA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: GUAC_STAA1
Sequence: MKIFDYEDIQLIPNKCIVESRSECDTTIQFGPKKFKLPVVPANMQTVMNEKLAKWFAENDYFYIMHRFDEEARIPFIKHMQNSGLFASISVGVKKAEFDFIEKLAQEKLIPEYITIDIAHGHSDSVINMIKHIKNHIPDSFVIAGNVGTPEGVRELENAGADATKVGIGPGRVCITKIKTGFGTGGWQLAALNICSKAARKPLIADGGIRTHGDIAKSIRFGASMVMIGSLFAAHEESPGETVELDGKQYKEYFGSASEFQKGEHKNVEGKKMFVEHKGSLMDTLKEMQQDLQSSISYAGGKDLKSLRTVDYVIVRNSIFNGDRD
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
Protein: MATP_VIBPA
Sequence: MKYQQLENLECGWKWKYLIKKWKDGEAITRHIDTSEADAAIAELRRIEHEPTLVLAWIEKHMSEELENKLKQAIRAKRKRHFNAEQVHTKKKSIDLDYRVWEKLSNRANELGCTLSDAIEYLLSEASRSEKASQKVTSIKEDLSKLLSS
What is the function of this protein?
Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle.  Prevents early segregation of duplicated Ter macrodomains during cell division.  Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.
What are the official names of this protein?
Macrodomain Ter protein.
What is the protein family that this protein belongs to?
Belongs to the MatP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASSY_STAAS
Sequence: MKEKIVLAYSGGLDTSVAVQWLIDKGYDVVACCLDVGEGKDLDIVYKKALDMGAVECHIIDATKEFSDEYVSYAIKGNLMYENAYPLVSALSRPLIAKKLVEIAEKTNSVGIAHGCTGKGNDQVRFEVAIKALNPSLKAFAPVREWAWSREEEIDYAIKHNIPVSINHDSPYSIDQNLWGRANECGILEDPYAAPPEDAFDLTNALEETPDAADEIILTFDKGIPVQIDGKTYELDDLILTLNALAGKHGIGRIDHVENRLVGIKSREIYEAPAAEVILKAHKALETITLTKDVAHFKPIIEKQFAEQLYNGLWFSPLTDSLKLFIDSTQQYVSGDVRIKLFKGNAIVNGRKSPYTLYDEKLATYTKEDAFNQDAAVGFIDIYGLPTQVNSMLHGGYSNEQ
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTH_STAAS
Sequence: MTLYLDGETLTIEDIKSFLQQQSKIEIIDDALERVKKSRAVVERIIENEETVYGITTGFGLFSDVRIDPTQYNELQVNLIRSHACGLGEPFSKEVALVMMILRLNTLLKGHSGATLELVRQLQFFINERIIPIIPQQGSLGASGDLAPLSHLALALIGEGKVLYRGEEKDSDDVLRELNRQPLNLQAKEGLALINGTQAMTAQGVISYIESEDLGYQSEWIAALTHQSLNGIIDAYRHDVHAVRNFQEQINVAARMRDWLEGSTLTTRQAEIRVQDAYTLRCIPQIHGASFQVFNYVKQQLEFEMNAANDNPLIFEEANETFVISGGNFHGQPIAFALDHLKLGVSELANVSERRLERLVNPQLNGDLPAFLSPEPGLQSGAMIMQYAAASLVSENKTLAHPASVDSITSSANQEDHVSMGTTAARHGYQIIENARRVLAIECVIALQAAELKGVEGLSPKTRRKYEEFRSIVPSITHDRQFHKDIEAVAQYLKQSIYQTTACH
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX121_URTEQ
Sequence: MCLLMLVLGAMYVQGWHSAGFGKRTLKKRCYPGQPGCGHCSRPNYCEGARCESGFHDCGSDHWCDASGDRCCCA
What is the function of this protein?
Potentiates activation of mammalian TRPA1, a non-selective cation channel involved in perception of pain, in vitro yet has an analgesic and anti-inflammatory effect in vivo.  Has antibacterial activity against C. glutamicum (MIC=50 uM) and, to a lesser extent, against S. aureus but not against P. aeruginosa or E. coli.
What are the official names of this protein?
Tau-AnmTx Ueq 12-1, Ueq 12-1.
What is the protein family that this protein belongs to?
Belongs to the Cnidaria small cysteine-rich protein (SCRiP) family.
What are the subcellular locations of this protein?
Secreted.
Protein: THS1_PAPSO
Sequence: MDSINSSIYFCAYFRELIIKLLMAPLGVSGLVGKLSTELEVDCDAEKYYNMYKHGEDVQKAVPHLCVDVKVISGDPTRSGCIKEWNVNIDGKTIRSVEETTHNDETKTLRHRVFEGDMMKDFKKFDTIMVVNPKPDGNGCVVTRSIEYEKTNENSPTPFDYLQFGHQAIEDMNKYLRDSE
What is the function of this protein?
Catalyzes the formation of thebaine from (7S)-salutaridinol 7-O-acetate at the expense of labile hydroxylated by-products, which are preferentially produced by spontaneous allylic elimination.
What are the official names of this protein?
Thebaine synthase 1.
What is the protein family that this protein belongs to?
Belongs to the MLP family.
Protein: APOE_PTEVA
Sequence: MKFLWAALVVTLLAGCRADVEEEVKLGQEPDRWQAKQPWEQALGRFWEYLRWVQTLSNKVKEELLNSQVTEELKLLIEETMKEVKAYKEELEKQVGPIAQETQARLSKELQAAQARLESDMEDVRTRLAQYRSEAQAALGQNTDDLQGRLASHLRKLRKRLLRDAEDLQKRLAVYQAGTREAAERGVSAVHERLGPLMMEGPLQAIPPSQQLRERAEAWGQKVRGRLESVGSQARDRLDDMRDQMEELKAKVEEQASQVRLQAEAFQTRLKSWFEPLVQDMQRQWASLVEKVQSTLGISPSTKPSKTK
What is the function of this protein?
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids.  APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance.  Apolipoproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma.  As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL).  It also binds a wide range of cellular receptors including the LDL receptor/LDLR and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles.  Finally, APOE has also a heparin-binding activity and binds heparan-sulfate proteoglycans on the surface of cells, a property that supports the capture and the receptor-mediated uptake of APOE-containing lipoproteins by cells.
What are the official names of this protein?
Apolipoprotein E, Apo-E.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix. Note=In the plasma, APOE is associated with chylomicrons, chylomicrons remnants, VLDL, LDL and HDL lipoproteins. Lipid poor oligomeric APOE is associated with the extracellular matrix in a calcium- and heparan-sulfate proteoglycans- dependent manner. Lipidation induces the release from the extracellular matrix.
Protein: FLGI_ECO8A
Sequence: MIKFLSALILLLVTTAAQAERIRDLTSVQGVRQNSLIGYGLVVGLDGTGDQTTQTPFTTQTLNNMLSQLGITVPTGTNMQLKNVAAVMVTASLPPFGRQGQTIDVVVSSMGNAKSLRGGTLLMTPLKGVDSQVYALAQGNILVGGAGASAGGSSVQVNQLNGGRITNGAVIERELPSQFGVGNTLNLQLNDEDFSMAQQIADTINRVRGYGSATALDARTIQVRVPSGNSSQVRFLADIQNMQVNVTPQDAKVVINSRTGSVVMNREVTLDSCAVAQGNLSVTVNRQANVSQPDTPFGGGQTVVTPQTQIDLRQSGGSLQSVRSSASLNNVVRALNALGATPMDLMSILQSMQSAGCLRAKLEII
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: NFUA_PSE14
Sequence: MTAITITDAAHDYLADLLEKQNTPGIGIRVFITQPGTQYAETCIAYCKPGEEKPEDKAIGLKSFTAWIDGFSEAFLDDAVVDYATDRMGGQLTIKAPNAKVPMVNADSPINERINYYLQTEINPGLASHGGQVTLIDVVEEEAKNIAVLQFGGGCQGCGQADVTLKEGIERTLLERIPELSGVRDVTDHTQKENAYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: P2C73_ARATH
Sequence: MGHFSSMFNGLARSFSIKKVKNNNGNCDAKEAADEMASEAKKKELILKSSGYVNVQGSNNLASLFSKRGEKGVNQDCALVWEGFGCQEDMIFCGIFDGHGPWGHYVAKQVRNSMPLSLLCNWQKILAQATLEPELDLEGSNKKISRFDIWKQSYLKTCATVDQELEHHRKIDSYYSGTTALTIVRQGEVIYVANVGDSRAVLAMESDEGSLVAVQLTLDFKPNLPQEKERIIGCKGRVFCLDDEPGVHRVWQPDAETPGLAMSRAFGDYCIKEYGLVSVPEVTQRHISTKDHFIILASDGIWDVISNQEAIEIVSSTAERPKAAKRLVEQAVRAWKKKRRGYSMDDMSVVCLFLHSSSSSSLSQHHHAMTILK
What are the official names of this protein?
Probable protein phosphatase 2C 73, AtPP2C73, AtPPC6;7.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: AROG_CANAL
Sequence: MSKTPVPTEYDDTRILGYDPLVPPALLQHEIKASAESLDVVIKGRYDSAQILKGNDDRCIVIVGPCSIHDPPQALEYGKRLKKLADELKDDLVIIMRAYLEKPRTTVGWKGLINDPDVDNSFDINRGLKISRQLYSDLTSVVGLPIGSEMLDTISPQYFSDFLSFGAIGARTTESQLHRELASGLSFPIGFKNGTDGGLAVALDAVQASSKGHHFMGVTKNGMAAITTTKGNDCCFIILRGGKKITNYDVESVKAAKEAIAKCTDPSIKLMVDCSHDNSRKDYRNQPQVLDSVAEQISNGEDSIIGVMIESNIHEGKQPMPPAGSGKEALKYGVSITDGCVSWETTVEMLTKLSQAVQTRRSLKKQKVSN
What is the function of this protein?
Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).
What are the official names of this protein?
Phospho-2-dehydro-3-deoxyheptonate aldolase, tyrosine-inhibited, 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase, DAHP synthase, Phospho-2-keto-3-deoxyheptonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class-I DAHP synthase family.
Protein: SLYA_ECO81
Sequence: MESPLGSDLARLVRIWRALIDHRLKPLELTQTHWVTLHNIHQLPPDQSQIQLAKAIGIEQPSLVRTLDQLEEKGLISRQTCASDRRAKRIKLTEKAEPLISEMEAVINKTRAEILHGISAEELEQLIKLIAKLEHNIIELQAKG
What is the function of this protein?
Transcription regulator that can specifically activate or repress expression of target genes.
What are the official names of this protein?
Transcriptional regulator SlyA.
What is the protein family that this protein belongs to?
Belongs to the SlyA family.
Protein: JOS2_HUMAN
Sequence: MSQAPGAQPSPPTVYHERQRLELCAVHALNNVLQQQLFSQEAADEICKRLAPDSRLNPHRSLLGTGNYDVNVIMAALQGLGLAAVWWDRRRPLSQLALPQVLGLILNLPSPVSLGLLSLPLRRRHWVALRQVDGVYYNLDSKLRAPEALGDEDGVRAFLAAALAQGLCEVLLVVTKEVEEKGSWLRTD
What is the function of this protein?
Cleaves 'Lys-63'-linked poly-ubiquitin chains, and with lesser efficiency 'Lys-48'-linked poly-ubiquitin chains (in vitro).  May act as a deubiquitinating enzyme.
What are the official names of this protein?
Josephin-2, Josephin domain-containing protein 2.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RF1_BRUA1
Sequence: MIALPQDRMDQLLKRFSMIESQMANNPDSDTYVKLASEYSELQDVVGKIRELSDARMEASDLAAMRDDASTDAEMRALAVEELPEVEKRIAVLEQDVQILLLPKDAADDKNAILEIRAGTGGLEATLFAGDLFRMYERYAAEKGWRVELVSASEGDAGGYKEIIATVSGKGVFSKLKFESGVHRVQRVPETEAGGRIHTSAATVAVLPEAEDIDIEIRNEDIRIDTMRASGAGGQHVNTTDSAVRITHIPTGIMVVQAEKSQHQNRARAMQILRARLYDMERQKAESERSQARRSQVGSGDRSERIRTYNFPQGRVTDHRINLTLYKLDRVMEGDLDELVDALISDHQTALLAELGEQP
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GMHA_PROMH
Sequence: MYQDLIRGELTEAADTLSRFLQDDANIEAIQKAAVLLADSFKAGGKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDVSHISCVSNDFGYEYVFSRYVEAVGKEGDVLLGISTSGNSGNIIKAISAAREKGMKVITLTGKDGGKMAGSADIEIRVPHFGYADRIQEIHIKVIHILIQLIEKEMEK
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_KOSOT
Sequence: MKVILLKDVAKLGKKGEIKEVSDGYGRNYLIPRGLAVEATKSELSKLKNIEDQKKKKEERTKANSEELLRKIKQRHFRMKVKAGASGKLFGAVTSADIAELIAKELGTEFSKRYVDLKENIKNTGEYKVNLKLPGNVKGSIIIAIEKSEED
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.