PharMolix/UniProtQA huggingface dataset:
Protein: CHS7_ASHGO
Sequence: MSSKEAPMRAWLKMAGLAMSNKSWLSLGDFAGICAKTPLPMCFVVQTSSLPGGSVGATHYDRTHMNIGMVPRCYSRTVDIANTAIFQLGNAFVNILALCVILIISYNIRFKYTAIGRSEYGYFFQLCFMLICMTLVVDCGVSPPGTLAYPYLAALQIGLAGACSWALAVMGFLGFRLWEDGTRKSMLIVRGVSMVGFLLGSLVSAITFTNWIQHHPDMKTNTTALFVVMYGLNGLALLMYSVCQLVVSIFVLSNFWMTGSTILGVIFITTGQVLMYTISYEICEGVKHYLDGLFIGSICNVFALMMIYKTWDISTDEDLEFSVSISVDGDIMYNSNLKL
What is the function of this protein?
Chaperone required for the export of the chitin synthase CHS3 from the endoplasmic reticulum.
What are the official names of this protein?
Chitin synthase export chaperone.
What is the protein family that this protein belongs to?
Belongs to the CHS7 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: TGT_CAMJD
Sequence: MEFKLKHKDGMARVCEITTAHSTFLTPVFMPVGTVGAVKSLDANDMKNELDAKIILANTYHMYLRPTSKVVKDFGGLHGFTKFDRSFLTDSGGFQAFSLSKNSKHFNEGIEFKSHIDGSRHLFTPKSVLDTQYDFHSDIMMILDDLVALPATKERVKISVDRTILWAKEAITYHKSMQNKGIGIGQNIFGIIQGGTDYEERKRCALSLNEMPFDGLAIGGLSVGEENALMYETVQNLNPYLDENRPRYLMGVGTPEDLVENVERGVDMFDCVMPTRNARNGTFFTSFGKFNIKKAEFINDHEAIGPACSCYTCRNFSRGYLNHLFKAKELTFFRLASLHNLHYYLELAREMREAILNNSFTQFKKNFYHLRGK
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: AKAP4_RAT
Sequence: MIAYCGTTKMSDDIDWLHSRRGVCKVDLYSPEGQQDQDRKVICFVDVSTLNVEDDSKGAAGPRSDGELNLENLEEKEIIVIKDTEKQDQPKTEGSVCLFKQAPSDPISVLNWLLNDLQKYALGFQHALSPSASSCKHKVGDLEGDYHKIPSENCYSVYADQVNLDYLNKGPQNLRLEMAASKNTNNNQSPSNPATKSPSNQRSVATPDGECSMDDLSYYVNRLSSLVIQMARKEIKDKLEGGNKCLHHSMYTSGEKGKTSPRSAVSKIASEMAHEAVELTSSEMRGNGEEGRDGRKTFLYSELSNKNKCGEKQQMCPKDSKEFADSISKGLMVYANQVASDMMVSVMKTLKVHSCGKPIPACVVLKRVLLKHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNHGKQNAADIMEAMLKRLVSALLGEKKETKSQSLAYATLKAGTHDPKCKNQSLEFSAMKAEMKGKDKGKTKGDPCCKSLTSAERVSEHILKESLTMWNNQKQGTQGRVPNKVCPSKDEKREKISPSTDSLAKDLIVSALMLIQYHLTQQAKGKDPCEEECPGSSMGYMSQSAQYEKSGGGQSSKSLSMKHFESRGAPGPSTCAKENQLESQKMDMSNMVLSLIQKLLSESPFSCDELSESENKRCCDSRSKQAAPVAKRPEDQSQDSTEMDFISGMKQMNRQFIDQLVESVMKLCLIMAKYSNNGAALAELEEQAALASNGPRCGREAVMSQSYLETPGPEVIVNNQCSTSNLQKQLQAVLQWIAASQFNVPMLYFMGDDDGQLEKLPEVSAKAAEKGYSVGDLLQEVMKFAKERQLDEAVGNMARKQLLDWLLANL
What is the function of this protein?
Major structural component of sperm fibrous sheath.  May play a role in sperm motility (By similarity).
What are the official names of this protein?
A-kinase anchor protein 4, AKAP-4, 75 kDa fibrous sheath protein, Major sperm fibrous sheath protein, Protein kinase A-anchoring protein 4, PRKA4.
What is the protein family that this protein belongs to?
Belongs to the AKAP110 family.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum. Note=Localizes to the principle piece of the sperm flagellum.
Protein: NUOI_BURPS
Sequence: MTAIQQFFKTFFLTELLKGLALTGRYTFKRKFTVQFPEEKTPISPRFRGLHALRRYENGEERCIACKLCEAVCPALAITIESETRADNTRRTTRYDIDLTKCIFCGFCEESCPVDSIVETQILEYHGEKRGDLYFTKDMLLAVGDRYEKEIAAAKAADARYR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CX031_HUMAN
Sequence: MYRMKRSQVRTPIRRLIRNVNLDWEDSMALGCTTVIERGTLRRLKRATLNTFLDSPVHVLLVMPKLIPEHWEKWEDVKR
What are the official names of this protein?
Putative uncharacterized protein encoded by LINC01545.
Protein: MTNC_SHESH
Sequence: MGIRAIVVDTAGTTTDLSFIKDTLFPYSAKALPDFLKENEHNVLVENCICDVRDIALEPEATLERVIEILQQWVAEDRKSTPLKTLQGLIWKQGYAKGEFTGHIFPDFIDAIEGIKQQNMRLYSFSSGSAEAQKLLFSHSDAGDLTPNFDGHFDTRTGNKLFKQAYCNIINTISLAPKQVLFISDVIEELKAAEEAGMRTLQMVRTPGQRTGTYKQISSFAELTF
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
Protein: NDK_STRMK
Sequence: MALERTLSIIKPDAVAKNVIGEIYARFEKAGLKVVAAKYKQLSRREAEGFYAVHRERPFFNALVEFMISGPVMIQALEGENAVLAHRDLLGATNPKEAAPGTIRADFAESIDANAAHGSDSVENAAIEIAYFFAATEVVSR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRP28_LODEL
Sequence: MSKRPIPIDDLLKEDAIVPKYIPKSKRAKSSNGPGEDGANTTLKLQYPQSSVNHGSAVSRSTQFSAHQKSSTRPTTSLQPPSKLRHKKFQFDWDDIDDPHYNPQPLYSFELDQLGVENGDNYNDNKNNNDDDDNFDFQDPLLHDDRNSGHWSTKLLSEMTDRDWRIFNEDYGITTKGKKIPHATRSWDESGLDPKILASLKSFGFRQPTPVQRASIPISLELRDVVGVAETGSGKTLAFLLPLLHYLSRVDGNYLNYEKVRNEPLALVLAPTRELALQITQEAEKFGKQLGFNVLSIIGGRQYQETMDQIDNMIVGRGVHIVVGTPGRLLDSVERKILNFSKCYYLVMDEADRMIDMGFEKDLNKLINLLPKNEKLSTTIDGKLFHLTKRLTMMYTATISPPIEKITKSYLIDPAYIYIGGAGEALDNIDQHFDYLSTYAESARLSKLIKVVQGHKRRNRNALVIIFANFKHVCDVLSLELEQNNLLNVVIHGSKSQEAREEALEDFRTHQAPILVATDVAARGIDVPNVSLVINYQMSKKFDEYIHRIGRTGRAGNLGESYTFLDDADAETFMPLKKFLKSGRKKVPEWLYRYNIG
What is the function of this protein?
ATP-dependent RNA helicase involved in mRNA splicing.  May destabilize the U1/5'-splice site duplex to permit an effective competition for the 5'-splice site by the U6 snRNA, resulting in the switch between U1 and U6 at the 5'-splice site.  May also act to unwind the U4/U6 base-pairing interaction in the U4/U6/U5 snRNP, facilitating the first covalent step of splicing (By similarity).
What are the official names of this protein?
Pre-mRNA-splicing ATP-dependent RNA helicase PRP28.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX23/PRP28 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: H2A1_CANAL
Sequence: MSGGKGKAGTSEKASTSRSAKAGLTFPVGRVHRLLRKGNYAQRIGSGAPVYLTSVLEYLAAEILELAGNAARDNKKSRIIPRHLQLAIRNDEELNKLLGDVTIAQGGVLPNIHQNLLPKKSGKGGVKASQEL
What is the function of this protein?
Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A.1.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: PHEA1_CHRSP
Sequence: KNGDLRAPYVEIFDARGCDAKNSQYTGPKSGDMNDDQCVKVSMAVPKVSEATAEKKRQEFLGFKETAINVPQIAGKTKKY
What is the function of this protein?
Light-harvesting photosynthetic tetrapyrrole chromophore-protein from the phycobiliprotein complex.
What are the official names of this protein?
Phycocyanin-645 alpha-1 chain, PC-645.
What is the protein family that this protein belongs to?
Belongs to the phycoerythrin family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Lumenal side.
Protein: SLX42_CANTT
Sequence: MSPEGEESHAEDNLYFHNTQMQSIHEETLAEESHAQAIQRSISRLSSFKHEDTDSESPIPVQKVIRQIKKTNTNTNTTKTKKRKLKVSKPRKNMSSSESVRQMYGSRKNGEQQGSIDGFLMSRFGEVDGCNESDRSSKLISQGEWESLSKFHEESNEKDKLLRKKIQRYYSEPQEELGEGCGMLTQASADPETKMTKEELESLYDLDSSTVFNQTTISAIGDMSEPTQVSEPCVVILSQTKVQSEASTQEDGADASVQEIKSTVPAQELFSTPEFVPAPLEQPVNKEMCSDQSIVVLEENVQSTQADDSDIVELISDSDPEPEEVSTKVQVLRSIYDSSGPVNDKQPSVASETVESDSTPIVSPVKTPQGTRMHVVQVASSNPSSPIKIVEENTEQQEEVFTDVESIYSTARTSFGTPKHTSPVILLESSDTDCDDNDNDVEPLSSMPMVKTVPKKRMRTTVLQVSAALKVQNYTDEKNNIKLRKIGDDIPVEVPTKDVEYEEIPDSQESVGGEGDNSVSIIEITREVHNNDYTGDESTDLFQVGLNKQDTCEDTSSPVVQIGGVENDILDSSLIEPVPEPESVPVPEEVQEQPQPTAIDKHTATQLREKFQLWGLKPVRGKEKMVEILQGISNFILPEHELLAVADKQELQSCIFRKLDAVIREGRAMYDRILSFEPIRLEELQSMLQSQDHYLELDVLRLYCDSSGITTTNA
What is the function of this protein?
Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination.  Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
What are the official names of this protein?
Structure-specific endonuclease subunit SLX4 2.
What is the protein family that this protein belongs to?
Belongs to the SLX4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EPMA_YERPB
Sequence: MSDTASWQPSAPIANLLKRAAIMAEIRRFFADRGVLEVETPTMSQATVTDIHLVPFETRFVGPGAADGLTLYMMTSPEYHMKRLLAAGSGPIYQLGRSFRNEEAGRYHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQILDCNSAETLSYQQAFLRHLNIDPLSAEKAQLREVAAKLDLSNIADTEEDRDTLLQLLFTVGVEPYIGRDKPAFIYHFPASQASLAEISTEDHRVAERFEVYFKGIELANGFRELTDGDEQLQRFEQDNRNRAKRGLPQNPIDMNLIAALKQGLPDCSGVALGVDRLVMLALNAERLSDVIAFPVNIA
What is the function of this protein?
With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P).  Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P.
What are the official names of this protein?
Elongation factor P--(R)-beta-lysine ligase, EF-P--(R)-beta-lysine ligase, EF-P post-translational modification enzyme A, EF-P-lysine lysyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
Protein: WAPI_BACNB
Sequence: MKFFKRYNIDQKTLDEFKKYYVLLHGPFPNDMYDFEEETNTSLDEFYEFFALITGSLNYIIEDKKIPRYQREMLKKTFYEHYPHFRNYKSDILKYQELSECLEFHEKIRILINKLITGG
What is the function of this protein?
Immunity protein component of a toxin-immunity protein module, which functions as a cellular contact-dependent growth inhibition (CDI) system.  Neutralizes the tRNase activity of cognate toxin WapA upon expression in E. coli.  Does not inhibit WapA from other strains of B. subtilis.  The WapA C-terminus cannot be expressed on its own in E. coli, however it can be cloned in the presence of its cognate immunity protein gene.  Cell contact is probably necessary for growth inhibition.
What are the official names of this protein?
Immunity protein WapI.
Protein: ECPC_EIKCO
Sequence: MLKQVQKGFTLIELMIVIAIIGILAAIALPAYQDYVARSQMSEAFNLAGGQKGAVSEYYSDKGVWPADNAAAGIAATVNGKYVNSVVVSAAGTNGVITATMKSTGVAKGVQGKTLALKGTANDGSFSWECSSNADAKYLPSSCRNAATPTPTP
What are the official names of this protein?
Fimbrial protein EcpC, Pilin.
What is the protein family that this protein belongs to?
Belongs to the N-Me-Phe pilin family.
What are the subcellular locations of this protein?
Fimbrium. Membrane; Single-pass membrane protein.
Protein: CLA2_CLACD
Sequence: MTSSGDSSPQIPIAIVGLGCRFPGDADSPKKFWDILKEGRDAYSPRTDRWNPDAFYHPNKDRANTQPTKGGHFLKQDPYVFDPSFFNITATEAIALDPKQRLALEVAYEALENAGFPLQKVAGSQTACYMGSAMADYRDSISRDFGHAPKYFVLGTCEEMISNRISHFFDMHGPSATVHTACSSSLVATHVACQSLRSGEADMALAGGVGIMLTPDSSLQLNNMSFLNPEGHSRSFDADAGGYARGEGCGILVMKRLDDAVRDGDNIRAVIRGSGVNSDGWTQGVTMPSPEAQAALIKQVFGKNKLDYDTIQYVEAHGTGTKAGDPVETKAIYDTIGRGINKSRKLWIGSVKPNIGHLEAAAGVAGIIKGVLSLENSAIPPNIYFSKPNPAIKLDEWNMAVPTKLVNWPVAQTKRMTVSGFGMGGTNGLVVLEAYVPERLLNGATKVTTAKDTAHSGKRLFVCSSQDQAGFKRIGEAFVDHLDNLGPIASSSGYLANLAHTLSTARAGLSWRTTFVADSKAELREHLTTTLGQDATRVSDTQAQRIGFVFTGQGAQWAGMGVEMLERPVFGASVAESAKLLRSFGCTWDPATELQKAAKESRLAVPEISQPICTIIQIALVDELKSWGVSPAKVVGHSSGEIAAAYTIGALSHRDAMAVAYFRGMASTALKTSAPHLEGGMMAVGTSAEAAQTIIAETKNSISGDITIACVNSPSSVTLSGDAKALEELRKILDARSVFARRLKVDVAYHSSHMNVAAPEYQQSIADIEPRLCSDEVEEGSLPVMVSSVTTEQVSPELLGTYYWIRNLVSPVQFSDALRELVAPGGSDKNDVDLLIEIGPHSALGGPIEQILSFHNVQKVDYKSVLTRGQNALDTSLSLASDLFVRGIQLDMEKVNGDSDCHLLNDLPSYPWNHSKAFRADSRIQRELLQSKHPRHSMIGLKQPMLDESQHVWRNYVRLTDEPWLRGHVVGGTALVPGAGMLSMIFEAVQQLVDPGKPAHSLRVRDVKFSAALTLPEDTSIEVVTTLRPHLVSTSGSTPASWWEFTISSCPGTDQIQDNCRGLVAIEYTNKRSEQMIYEDVNEENSRIADFHRVRDESPLMIRREKFYEHMQKSGYNYGETFQGMETVHLGDGETAFHVKLIDIGETFSKGQLDRPFLIPGSSLDAIFQSIFGSTFKNGAFEVEKPNFLAYIGELEISLDIPGEVGYVMPGVCFSRKHGFNQQSADIFTFDKSLSRMHLAVRDFRMTEPEVGDDASDGFEPWAFTSAPHWNYAFSLLKTEELRSVLSKVTTQDAPVELLRTILHENPSASVLELIPEIGDLAIASSYQLPKGAIQPSQLRYAVAKDIPDSFIDENLVGEVFALDGVGEDDRKISADVLIVPSSLDLLEDRDAILARFLKLAGPAALMITASGLHSARSVFEAHGFQAFPGLNGIASLPGLYSHAEEPSLRQTNRGTRDTSDTDITILEPSSPSFNTTEFSKTLSSRLEDQNYSVTIRKWAGGETEEFQNTTYISLLELEQPFLDNLSDPDFQGIKNLVLGSNRLIWLTLGDDPSFGAVDGLSRVMRSELGTPKFQVMHLSGEAGLLSGPELTVRVLKSPTEDTEFRERDGLLQVIRIFESPDVNQSLRGHLENSTRILPIKQLDYPVRLTVGKPGFLDSLQFIKDRRTEAPLPENEIEIDVHASGVNFRDVMASMGLISTPILGFEASGVVTKCGSQVSQFRTGARVSFVGEHTHSTRIRADPRLVAPIPDDVSFEEAASLPIVGATAYHTLTNLARLRKGQTILIHAAAGGVGQAMIQLASHFGLVIYATVGTEDKRKLLGEKYNIPPENILNSRDASFAKGIKRLTGGRGVDCVINSLSGELLRASWGCVAPFGIFIELGLRDITDNMRLDMRPFSNVTSFTFCNILALMQQDPDAMGLVLKETFKLVSQGILTSPFPTTVFPVEQTQEAFRLMQQGKHRGKLVLSFAGDPQAPVHCEAKESLRLDGNATYLIIGGLGGLGRSMALELVASGARHLAFISRSGDSTPQAKATLAELEQRNLDFRVYRGDVSNEESFLDAMKLCSSDLPPIKGVIQMAMVLKDIIFEKMTHEQWTIPLRPKIQGTWNIHQYFDESRPLDFMVFCSSTSGIHGYPSQSQYAAGNTYQDTLAAYRRAHGLKAVAVNLTIIREVGILAEQGTTGNIAVWEEALGIKEPAFHALMKTLIAGQQGPAGSEFLPPQVSTGLGTADIMSSYNLALPDYFQDPRFGPLAVSTFSTNVAGESQSAAVSLSSKLIEATNVDQASEIITEGLVTKVADMLQIPVSEVDASRPMYRYGVDSLVALEVRNWIVKEMKATIALLEILAAVPMNVLAKTIASRSKHLAATLD
What is the function of this protein?
Highly reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of cladosporin, a tricyclic octaketide that acts as an antimalarial agent though inhibition of the Plasmodium falciparum lysyl-tRNA synthetase (PubMed:26783060).  The highly reducing polyketide synthase cla2 is responsible for biosynthesis up to the pentaketide stage, including of the tetrahydropyran (THP) ring, whereas the three subsequent ketide extensions with no reduction are catalyzed by the non-reducing polyketide synthase cla3 (PubMed:26783060).
What are the official names of this protein?
Highly reducing polyketide synthase cla2, Cladosporin biosynthesis cluster protein 2.
Protein: NUOK_SHIF8
Sequence: MIPLQHGLILAAILFVLGLTGLVIRRNLLFMLIGLEIMINASALAFVVAGSYWGQTDGQVMYILAISLAAAEASIGLALLLQLHRRRQNLNIDSVSEMRG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NR4A1_HUMAN
Sequence: MPCIQAQYGTPAPSPGPRDHLASDPLTPEFIKPTMDLASPEAAPAAPTALPSFSTFMDGYTGEFDTFLYQLPGTVQPCSSASSSASSTSSSSATSPASASFKFEDFQVYGCYPGPLSGPVDEALSSSGSDYYGSPCSAPSPSTPSFQPPQLSPWDGSFGHFSPSQTYEGLRAWTEQLPKASGPPQPPAFFSFSPPTGPSPSLAQSPLKLFPSQATHQLGEGESYSMPTAFPGLAPTSPHLEGSGILDTPVTSTKARSGAPGGSEGRCAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQPPDASPANLLTSLVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQCARGFGDWIDSILAFSRSLHSLLVDVPAFACLSALVLITDRHGLQEPRRVEELQNRIASCLKEHVAAVAGEPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTLPF
What is the function of this protein?
Orphan nuclear receptor.  May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration.  Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity).  May inhibit NF-kappa-B transactivation of IL2.  Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation.  Plays a role in the vascular response to injury (By similarity).
What are the official names of this protein?
Nuclear receptor subfamily 4 group A member 1, Early response protein NAK1, Nuclear hormone receptor NUR/77, Nur77, Orphan nuclear receptor HMR, Orphan nuclear receptor TR3, ST-59, Testicular receptor 3.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR4 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Mitochondrion. Note=Nuclear export to the cytoplasm is XPO1-mediated and positively regulated by IFI27 (PubMed:22427340). Translocation to the mitochondrion upon interaction with RXRA and upon the presence of 9-cis retinoic acid (PubMed:17761950).
Protein: PANC_RHORT
Sequence: MRALPIARSVSELRAVVDGWKAEGLRVGLVPTMGALHAGHLSLVRLALSKVDRVVASVFVNPTQFGPNEDFAAYPRDEAADAAKLGGAGAHLLYAPDVAGMYPPGFSTTITVSGVSSGLCGDLRPGHFQGVATVVAKLFLRVRPDVAVFGEKDYQQLLVLKRLVNDLDLAIEVIGAPIVRETDGLALSSRNAYLSAEQRALAPGLYRTLRRVGADILGGGRVDDCLAWGIDELKALGFGPVDYLDLRDGATLERLDDAPEGPGRLLCAAYLGKTRLIDNIGV
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3199_BACCQ
Sequence: MSSSNLNEISKQILKEEETLQFSSFTNEDALQIGLFIVETAKREGKLIAVDITKNGVQLFHFKMTGTNAENTKWIERKKRVVSLHDRSSYYMQIQSEITGISYNEKYLLDTSEYAAFGGCFPIRIKNVGVIGMITVSGLPPEEDHELVVRAVKNHLNQ
What are the official names of this protein?
UPF0303 protein BCQ_3199.
What is the protein family that this protein belongs to?
Belongs to the UPF0303 family.
Protein: LPXC_PSEFS
Sequence: MIKQRTLKNIIRATGVGLHSGEKVYLTLKPAPVDTGIVFVRADLDPVVQIPARAENVGETTMSTTLVNGDVKVDTVEHLLSAMAGLGIDNAYVELSASEVPIMDGSAGPFVFLIQSAGLEEQDAAKKFIRILREVTVEDGDKRATFVPFEGFKVSFEIDFDHPVFRDRTQSASVDFSSTSFVKEVSRARTFGFMSDIEYLRKHNLALGGSVENAIVVDADGVLNEDGLRYEDEFVKHKILDAIGDLYLLGNSLIGEFKGFKSGHALNNQLLRKLIEQTDAWEVVTFEDASTAPISYMRPVAAV
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: DF124_ARATH
Sequence: MSKPTVIVIFMAILVLGMATKETQGANCVNYFEITFPEVCEANWCAAECLKAYKNGKGTCWQKFCQCVYDC
What are the official names of this protein?
Defensin-like protein 124, Low-molecular-weight cysteine-rich protein 16, Protein LCR16.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: GRPE_AROAE
Sequence: MQENKQPSEIQGELPQPPDGESVPPQPTNEQAPPDTDTMPRIEETLRQLELKAAEHHDAWLRARAETENVRRRAQEDIAKASKFAAEKFAAAMLPVKDSLEAALTIEKQTLESLREGVELTLKQLNAAFQNGGLTEEDPAGQKFDPNKHQAISAIEAEGEPNTVLNVLQKGYLLHGRVIRPAMVMVSKAKGT
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASTB_PSESM
Sequence: MKSCEVNFDGLVGPTHNYGGLSYGNVASQSNSQQCSNPREAALQGLAKMKALMDMGFTQGVLAPQERPDVASLRQLGFTGSDEQVIEKAARQDMPLLVASCSASSMWVANAATVSPSADTADGRVHFTAANLNCKYHRSIEHPTTSRVLGAMFADAKHFAHHPALPSVAQFGDEGAANHTRFCQDYGQAGVEFFVFGRSAFDTRYAAPQKYPARQTLEASRAVARLHGLSDECVVYGQQNPAVIDQGVFHNDVIAVGNGEVLFYHEDAFLHTEQMLGELRDKLSRAGGQLQAVCVPRAEVSVQDAVRSYLFNSQLLSRPDGSMLLIVPQECQANANVWGYLQRLIADAGPVAEVKVFDLKQSMQNGGGPACLRLRVALNETELAAVNPGVIMTAPLYETLTQWVDRHYRDRMSENDLADPRLLTECRTALDELTQILKLGAVYPFQLN
What is the function of this protein?
Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
What are the official names of this protein?
N-succinylarginine dihydrolase.
What is the protein family that this protein belongs to?
Belongs to the succinylarginine dihydrolase family.
Protein: PCRB_BACCN
Sequence: MYDISKWKHVFKLDPNKEISDEHLEMICESGTDAVIVGGSDGVTIDNVLHMLVSIRRYAVPCVLEVSNVEAITPGFDFYYIPSVLNSRKVEWLTGVHHEALKEFGDIMNWDEIFMEGYCVLNPEAKVAQLTEAKCDLTEDDVIAYARMADKLLHLPIFYLEYSGTYGDVELVKKVKAELQQAKLYYGGGISNVKEAKEVAQYADTVVVGNVIYENIKAALQTVKAVKGE
What is the function of this protein?
Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP).  This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales.
What are the official names of this protein?
Heptaprenylglyceryl phosphate synthase, HepGP synthase, Glycerol-1-phosphate heptaprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GGGP/HepGP synthase family. Group I subfamily.
Protein: RS171_ARATH
Sequence: MGRVRTKTVKKSSRQVIEKYYSRMTLDFHTNKKILEEVAIIPSKRLRNKIAGFSTHLMKRIQKGPVRGISLKLQEEERERRMDFVPDESAIKTDEIKVDKETLEMLASLGMSDTLGISAVDPQQAMAPIPAFGGGRAPRRY
What are the official names of this protein?
40S ribosomal protein S17-1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS17 family.