PharMolix/UniProtQA huggingface dataset:
Protein: ABFA_ASPTN
Sequence: MVAFSTISGLGALSLLFSIIESVDGVSLKVSTDGGNSSSPLLYGFMFEDINHSGDGGIYGQMIQNNGLQGSSPNLTAWASVGDGTISVDTTNPLTAAIPNSLKLDIKPDATGAVGFTNEGYWGIPVDGTEFQNSFWMKGDFSGEITVRLVGNETGTEYGSTTFNQSSSSDDYTKVSVKFPTTKAPDGNVLYELTVDGESAQGSSLSFTLFELFAQTYKSRSNGLKPQLADALESVKGSFLRFPGGNNLEGNDVETRWKWNETIGPLENRPGHQGTWGYFNTDGLGLDEYLYWCEDMNLTPVLGVWAGFALESGGNTPITGDALTPYIEDVLNELEYVLGDPSTTYGKLRASYGREEPWNVTLVEIGNEDNLGGGCESYAERFTAFYNAIHDAYPDLTLIASTDNASCLPSPLPEGAWVDYHNYNTPDELVKQFGMFDNVDRSVPYFIGEYSRWEIPWPNMQGSVAEAVFMIGLERNSDVVKMAAYAPLLQLVNSTQWTPDLISFTQNPNMVIDSTSYYVQQMFSVNRGDTIKEVTSDSAFGPVYWVASSSGSSYYVKLANYGADTQEVSVSIPGMSSGKLTVLADSDPEAYNSDTQTLVTPSESNVQASNGQFSFTLPAWSVAVLTAN
What is the function of this protein?
Alpha-L-arabinofuranosidase involved in the degradation of arabinoxylan, a major component of plant hemicellulose.  Acts only on small linear 1,5-alpha-linked L-arabinofuranosyl oligosaccharides (By similarity).
What are the official names of this protein?
Probable alpha-L-arabinofuranosidase A, ABF A, Arabinosidase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 51 family.
What are the subcellular locations of this protein?
Secreted.
Protein: CLPX_SALPK
Sequence: MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRERSALPTPHEIRTHLDDYVIGQEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVIANRVETGSGIGFGATVKAKSDKASEGELLSQVEPEDLIKFGLIPEFIGRLPVVATLNELSEEALIQILKEPKNALTKQYQALFNLEGVDLEFRDEALDAIARKAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDESVIAGQSKPLLIYGKPEAQASGE
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: H2B1_ORYSJ
Sequence: MAPKAEKKPAEKKPAAGEEKSAEKAPAGKKPKAEKRLPASKASSKEGGAGDKKGRKKAKKSVETYKIYIFKVLKQVHPDIGISSKAMSIMNSFINDIFEKLAQEAARLARYNKKPTITSREIQTSVRLVLPGELAKHAVSEGTKAVTKFTSN
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.1.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: CRZA_ASPFU
Sequence: MASQEMFPELGQSPAPGVKSRGVSRSPHPHQQQQQQQHQQHQGQFTGTVTGLDLDSSIATASSFANSSFDPNSNNVSPSAESYGYTAAGYLSGTPASQTDQNYANSLQIPQSYGTGLVPQFNESRGLPIQQQSQQQHHQQPSLDDNFSDLLNSNATEYDFNTVYQTHSPSSNTAPEYDSSLLLDPQVHQQSHPTQIPSSHSSTSPQISPLEQQQHSSPGPMSTQGSTTVAYYTPQHSRHASLDPATAAFLTSNTHPDWQAVMGNSAAFQGHRRAPSEVSEISSAAPSPYLSQHESFDGVDNNPSPLLAPQNDPSLYDSALGIENFTLSEQHQQHQGFSPAHSPYISPRLMPQQGQEMMPNVPYLSGPAPNTQYPTPPNDMYGNGAEGMMNMSQGTHPSVDIGQASQMAPPSINVEFAPPSRIPSFGPSKPASNLDSLSPPPSSTRSRGRSKSDPYAHPSTSRLRSSSTSSSLDPLAPTTPRSLSPFDSFGRQQQSNPSSRDPSPSRSNRRLSTSSIDSRNYILGLADPQRPGASPNDSKRVQKHPATFQCNLCPKRFTRAYNLRSHLRTHTDERPFVCTVCGKAFARQHDRKRHEGLHSGEKKFVCQGELSRGGQWGCGRRFARADALGRHFRSEAGRICIKPLLDEESQERERSLMDQQQHHLQPLPQQVMVPVDNPHAGNFVLPAALLAQYPALQTLQWDQIAASADDPSDIGGRSSFDASSGNEFGFEDDDSGLSSVSGINAGYSAAGNFY
What is the function of this protein?
Transcription factor involved in the regulation of calcium ion homeostasis (PubMed:18298443).  Regulates genes encoding calcium transporters, transcription factors and genes that could be directly or indirectly involved in calcium metabolism (PubMed:20078882).  Supports especially pmcA, pmcB and pmcC expression encoding for calcium-translocating P-type ATPases (PubMed:18298443, PubMed:22649543).  Binds target promoters at motif A[GT][CG]CA[AC][AG] (PubMed:25196896).  Plays an essential role germination, radial growth, and asexual development (PubMed:18456861, PubMed:18298443).  Also plays a major role in proper chitin and glucan incorporation into the cell wall (PubMed:19015336).  Involved in the high-osmolarity glycerol response (HOG) signaling pathway (PubMed:25196896).  Required for pathogenicity in an experimental murine model of invasive pulmonary aspergillosis (PubMed:18456861, PubMed:18298443, PubMed:22649543, PubMed:25196896).
What are the official names of this protein?
C2H2 finger domain transcription factor crzA.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Localizes predominantly to the cytosol of the cell in the absence of added calcium and translocates to the nucleus following exposure to CaCl(2).
Protein: PDLI7_BOVIN
Sequence: MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGGLTHIEAQNKIRACGERLSLSLSRAQPAQSKPQKVQTPDKQPLRPLVPDASKQRLMEDTEDWRPRPGTGQSRSFRILAHLTGTEFMQDPDEEHLKKSSQVPRTEAPTPASATPQEPWPGPTTPSPTSRPPWAVDPAFAERYAPDKTSTVLTRHTQPATPTPMQNRTSIVQAAAGGGHGGGGGSNGKTPVCHQCHKVIRGRYLVALGRAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSCAKCKKKITGEVMHALKTTWHVHCFTCAACKAPIRNRAFYMEEGAPYCEPDYEKMFGTKCRGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDKPLCKSHAFSHV
What is the function of this protein?
May function as a scaffold on which the coordinated assembly of proteins can occur.  May play a role as an adapter that, via its PDZ domain, localizes LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues.  Involved in both of the two fundamental mechanisms of bone formation, direct bone formation (e. g.  embryonic flat bones mandible and cranium), and endochondral bone formation (e. g.  embryonic long bone development).  Plays a role during fracture repair.  Involved in BMP6 signaling pathway (By similarity).
What are the official names of this protein?
PDZ and LIM domain protein 7.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Note=Colocalizes with RET to the cell periphery and in some cytoskeletal components. Colocalizes with TPM2 near the Z line in muscle. Colocalizes with TBX4 and TBX5 to actin filaments (By similarity).
Protein: ILVC_BACVZ
Sequence: MVKVYYNGDIKENVLAGKKVAIIGYGSQGHAHALNLKESGIDVIVGVRQGKSFTQAQEDGHQVFSVREAAAQADIIMVLLPDEQQQKVYEAEIKDELTAGKSLVFAHGFNVHFHQIVPPADVDVFLVAPKGPGHLVRRTYEQGAGVPALFAIYQDVSGEAKDTALAYAKGIGGARAGVLETTFKEETETDLFGEQAVLCGGLTALVKAGFETLTEAGYQPELAYFECLHELKLIVDLMYEEGLAGMRYSISDTAQWGDFVSGPRVVDAKVKESMKQVLTDIQNGTFAKEWIVENQVNRPRFNAINASENEHQIEKVGRQLREMMPFVKQGKKKEAVVSVAQN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: UNG_VAR67
Sequence: MNSVTVSHAPYTITYHDDWEPVMNQLVEFYNEVASWLLRDETSPIPDKFFIQLKQPLRNKRVCVCGIDPYPKDGTGVPFESPNFTKKSIKEIASSISRLTGVIDYKGYNLNIIDGVIPWNYYLSCKLGETKSHAIYWDKISKLLLHHITKHVRFLYCLGKTDFSNIRAKLESPVTTIVGYHPAARDRQFEKDRSFEIINVLLELDNKAPINWAQGFIY
What is the function of this protein?
Plays an essential role in viral replication as a component of the DNA polymerase processivity factor.  Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
Protein: PSBA_CONJP
Sequence: MTATLERRESASIWGRFCNWVTSTETRLYIGWFGVLMIPTLLTATSVFIIAFIAAPPVDIDGIREPVSGSLLYGNNIISGAIIPTSAAIGLHFYPIWEAASVDEWLYNGGPYELIVLHFLLGVACYMGREWELSYRLGMRPWIAVAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANAGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGIWFTALGISTMAFNLNGFNFNQSVVDSQGRVINTWADIINRANPGMEVMHERNAHNFPPNLAAIEAPAVNG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: TRMB_LEPIN
Sequence: MVQDLEQKLWSIASGIPFSSDYFLQASPIRKLKKENLFSKVFETYFLELGSGWGEVAISMALQRPNTGFILMEKKFDRIRHTIREIEKHSLDNVKILCVNFNWFLEEVFEENLFSEILLNFPDPWPKKRHHKKRTVNSKFLESLKILLPEKGKFYFATDYGPYARKVIRLFRDSKAFSPEKVELKSERNEIPVSHFERKKREEGKRIYYIDRVLVQK
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: MALQ_THELN
Sequence: MERINFIFGIHNHQPLGNFGWVFEEAYNRSYRPFMEILEEFPEMKVNVHFSGPLLEWIEENKPDYLDLLRSLIKRGQLEIVVAGFYEPVLAAIPKEDRLVQIEMLKDYARKLGYDAKGVWLTERVWQPELVKSLREAGIEYVVVDDYHFMSAGLSKEELFWPYYTEDGGEVITVFPIDEKLRYLIPFRPVKKTIEYLESLTSDDPSKVAVFHDDGEKFGVWPGTYEWVYEKGWLREFFDAITSNEKINLMTYSEYLSKFTPRGLVYLPIASYFEMSEWSLPAKQAKLFVEFVEQLKEEGKFEKYRVFVRGGIWKNFFFKYPESNFMHKRMLMVSKAVRDNPEARKYILKAQCNDAYWHGVFGGIYLPHLRRTVWENIIKAQRYLKPENKILDVDFDGRAEIMVENDGFIATIKPHYGGSIFELSSKRKAVNYNDVLPRRWEHYHEVPEATKPEKESEEGIASIHELGKQIPEEIRRELAYDWQLRAILQDHFIKPEETLDNYRLVKYHELGDFVNQPYEYEMIENGVKLWREGGVYAEEKIPARVEKKIELTEDGFIAKYRVLLEKPYKALFGVEINLAVHSVMEKPEEFEAKEFEVNDPYGIGKVRIELDKAAKVWKFPIKTLSQSEAGWDFIQQGVSYTMLFPIEKELEFTVRFREL
What is the function of this protein?
Catalyzes the transglycosylation of maltooligosaccharides, yielding maltooligosaccharides of various lengths and glucose.  Maltose and glucose can be used as acceptors in the transfer reaction.
What are the official names of this protein?
4-alpha-glucanotransferase, Amylomaltase, Disproportionating enzyme, D-enzyme.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 57 family.
Protein: PUR9_CHLAA
Sequence: MIGEERVVRALMSVYDKTGIVEFAQALHNLGIEIISTGQTQRVLREAGIPALPVSDVTGFPEILDGRVKTLHPAIHAGLLARRDVPAHMAELAAHNLQPIDLVVVNLYPFAATIARPDVTMAEAQEQIDIGGVALLRAAAKNFPAVLVLVDPADYAGVLDGLRAGDVPLSERQRLAAKAFAHTAEYDATIAAYLRTEPLPDVLPLAWRKYQPLRYGENPHQAAALYGDFGAFFHQLHGKELSYNNILDTAAAQELIEEFPATEAAAVAIIKHTNPCGVAIAADLHRAWEAAFATDREAPFGGIIAVNRPVDIAFAEAVDEIFSEIIIAPDFAPDALALLRRKKNRRLLQSVRPITGADRWQLRSVPGGVLVQEPDHAPLVAEEWRVVTKRAPTDAEAAALRFAWRVVKHVKSNAIVYAAHDRTLGIGAGQMSRVDSSRLAVWKAQQAGIDLRGSVVASDALFPFADGVEAAIAAGATAIIQPGGSVRDEEVIAAADAAGAAMVFTGRRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: MTNN_KLEP7
Sequence: MKIGIIGAMEEEVTLLRDKIENRQTITIGGSEIYTGQLHGVDVALLKSGIGKVAAAMGATLLLERCQPDVIINTGSAGGLASTLKVGDIVVSDEARYHDADVTAFGYEYGQLPGCPAGFKADEKLVAAAESCIKALDLNAVRGLIVSGDAFINGSVGLAKIRHNFPQAIAVEMEATAIAHVCHNFKVPFVVVRAISDVADQQSHLSFEEFLAVAARQSTLMVENLVQNLARG
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.  Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: MDTC_SALNS
Sequence: MRFFALFIYRPVATILIAAAITLCGILGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEMTSSSSLGSTRIILEFNFDRDINGAARDVQAAINAAQSLLPSGMPSRPTYRKANPSDAPIMILTLTSESWSQGKLYDFASTQLAQTIAQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDEVREAIDSANVRRPQGAIEDSVHRWQIQTNDELKTAAEYQPLIIHYNNGAAVRLGDVASVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDGIRAKLPELRAMIPAAIDLQIAQDRSPTIRASLQEVEETLAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENIARHLEAGMKPLQAALQGTREVGFTVISMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLVVSLTLTPMMCGWMLKSSKPRTQPRKRGVGRLLVALQQGYGTSLKWVLNHTRLVGVVFLGTVALNIWLYIAIPKTFFPEQDTGVLMGGIQADQSISFQAMRGKLQDFMKIIRDDPAVNNVTGFTGGSRVNSGMMFITLKPRGERKETAQQIIDRLRVKLAKEPGARLFLMAVQDIRVGGRQANASYQYTLLSDSLAALREWEPKIRKALSALPQLADVNSDQQDNGAEMNLIYDRDTMSRLGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYSQDISALEKMFVINRDGKAIPLSYFAQWRPANAPLSVNHQGLSAASTIAFNLPTGTSLSQATEAINRTMTQLGVPSTVRGSFSGTAQVFQQTMNSQLILIVAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRSGGLTPEQAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLRFSRKNSKPVVEI
What are the official names of this protein?
Multidrug resistance protein MdtC, Multidrug transporter MdtC.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DF301_ARATH
Sequence: MEKVTSIFFVLLLISSCLILRSQGQFRCKSVAECDSRGCRVGTHVICNEHHICTCAHGSPIGGQCDGVEDCDLSGCPPNSHVICDRIGGNFCTCVPN
What are the official names of this protein?
Defensin-like protein 301.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: MURC_LACDB
Sequence: MLDKTKQIWFIGIKGTGMASLALILHDLGYKVAGSDIDKYTFTQDPLEAAGIEVASFSKDNIKESGQVIVKGNAFKSDNIEVAACEEKGVKWQSYPDTVEEIVQQYTSIGVAGSHGKTSTTGLLATVLGEAAPTSFLIGDGMGKGVKDSRFFVYEADEYRRHFLAYHPDYQIMTNVDFDHPDYFKDRDDYASAFQTAADQTKKGLFVWGDDERLQKIHPKTAKKYTYGLKDSDDFQAFDVVKTTEGAKFHVRANGEDLGEFTIHLFGDHNVMNATAVIAIAFTEGIDLDVVRKGLVKYTGAKRRFSEKDFGDTVVIDDYAHHPTELRATIQAARQKFPDRKLVTIFQPHTYSRTKEFEEEYVEILKGVDKAFLTPIYGSAREAAGDIKSEDIASQIPGAEVIDFDNLKDLLAYKGDCIVFMGAGDIPKYEVAFEEMLGK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBL_PSEAE
Sequence: MSSADSTPPWLTLVGIGEDGYPGLGKQARRALLQASRIVGAARQLELLPPCIGAARETWPTPFSLEPLLARRGQPTCVLASGDPMLFGVGASLARQLPATELRVLPAPSSLSLAAARLGWALQEVACLSLVARPLAALQAQVHDGRRLLVLSNDGDSPAAIARLLNARGFGASRLSVLEHLGGPLERRLDGLAGDWSLPRAADLNLVAVECRAGAGAVRLPLTPGLADEAYRHDGQLTKRDVRAVTLARLAPCPGELLWDVGAGCGSIGIEWMRAHPSCRAIAIEANDERQEHIRHNRDALGVPTLHLVAGSAPEALLELPEPDAIFIGGGVTAEGVLETCWERLRPGGRLLANAVTLQSERVLLDWQQRLGGDLTRLGVAHARPLGGFDTWRQALPITLLELRKPAARKPPRDA
What is the function of this protein?
Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X.
What are the official names of this protein?
Precorrin-6Y C(5,15)-methyltransferase [decarboxylating], Precorrin-6 methyltransferase, Precorrin-6Y methylase.
What is the protein family that this protein belongs to?
Belongs to the precorrin methyltransferase family.
Protein: Y1476_AQUAE
Sequence: MMLKSLTMENVKVVTGEIEKLRERIEKVKETLDLIPKEIEELERELERVRQEIAKKEDELIAVAREIRHKEHEFTEVKQKIAYHRKYLERADSPREYERLLQERQKLIERAYKLSEEIYELRRKYEALREEEEKLHQKEDEIEEKIHKLKKEYRALLNELKGLIEELNRKAREIIEKYGL
What are the official names of this protein?
Uncharacterized protein aq_1476.
Protein: RU1C_RAT
Sequence: MPKFYCDYCDTYLTHDSPSVRKTHCSGRKHKENVKDYYQKWMEEQAQSLIDKTTAAFQQGKIPPAPFSAPPPAGAMIPPPPSLPGPPRPGMMPAPHMGGPPMMPMMGPPPPGMMPVGPAPGMRPPMGGHMPMMPGPPMMRPPARPMMVPTRPGMTRPDR
What is the function of this protein?
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome.  SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing.  The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA.  Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
What are the official names of this protein?
U1 small nuclear ribonucleoprotein C, U1 snRNP C, U1-C, U1C.
What is the protein family that this protein belongs to?
Belongs to the U1 small nuclear ribonucleoprotein C family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GT17_ARATH
Sequence: MTFNKRQVKINHWPEKNDKEKQKYSKNRETVKLTLLTLLLLCSICFLFLTLNFPFTIEFTASIPRTCDHNFTVYVYDLPKEFNIGLLQNCRHLNIYTNMCPHVANNGLGQPLHRGRTSWFSTHQFIAEMIFHARVENHPCRTYEPDTADIFYVPFYGGLYASSVFREQNLTKRDELAVRLVNYISGQRWWKRSNGRDHFLAIGRTAWDFMRSSDTDFGANMLMQMPRVMNMSVLTVERQPWNGDNHFGIPYPSYFHPYTSAEMVTWQDKMKNVERPNLFSFVGGPRKGLEKAAIRDELIKQCAESSHCELLKCENGGSRCHNPMTVLGVMARSRFCLQAPGDSFTRRSTFDAMLAGCIPVFFSPHTMYTQYMWYLPDDKRSYSVFMDEKNNTHIEQELLRISENEVVQMREIVIDLIPRLTYAHPNSTNYDLPDAVDIALEALAKQARDNVVVSL
What is the function of this protein?
Functions in xyloglucan synthesis by adding side chains to the xylosylated glucan backbone.  Involved in the galactosylation of hemicellulose xyloglucan.
What are the official names of this protein?
Probable xyloglucan galactosyltransferase GT17, Glycosyltransferase 17, AtGT17.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 47 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: SUCC_HYDS0
Sequence: MKLHEHQSKELLKKYGLPVPEGYAAFNVKEAKEAAQALGGYPLVVKAQIHCGARGKAGGVKIVKSDEELEAFSEAILGKILKTVQCPNGKVVSRLLIEKATPIEKEFYLSITLDRSNSKILIMASKEGGMEIEELSKEKPDAIIKEYVDPVLGIMPYQTRKLSFALGLNPSLFGKIVSKLYQAYMDLDASLLEINPLVLTKDGDIVLLDAKVEIDDNAAFRHKDIEELEDITQIDPLEVEAKKYGLNYIKLEGNIGCMVNGAGLAMTTMDIIKLAGGAPANFLDVGGGASVEQIANAFRILTSDENVKAVFINIFGGILRCDRLANGLIEAAKIVNIKIPVVVRLEGTNVEEGRKLLKESGLNFESAVDMWDGAQKAIKLAQ
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: RL14_NOSP7
Sequence: MIQPQTYLNVADNSGARKLMCIRVLGGGNRRYGFIGDKIIAVVKDATPNMAVKKSDVVEAVIVRTRKAVSRDSGMSIRFDDNAAVIINKDGNPRGTRVFGPVARELRDKNFTKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: HFQ_VIBCM
Sequence: MAKGQSLQDPFLNALRRERIPVSIYLVNGIKLQGQIESFDQFVILLKNTVNQMVYKHAISTVVPARPVSHHSGDRPASDRPAEKSEE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: RL7_CHLCV
Sequence: MTTQSLETLVETLSNLTVLELAALKKLLEDKWDVTAAAPMMAVAAGAAVGGDAAPAESTEFAVILEDVPADKKIGVLKVVREVTGLALKEAKEMTEGLPKTVKEKTSKSDAEDTVKKLQDAGAKASFKGL
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: MU184_SCHPO
Sequence: MLARPETDTSVDYYAILKLQKNATFQQIRKQYLFLALQYHPDRNPGDEERAVKRFQRLQLAHEVLSDATKRLIYDQLFGLSTRTRSQYKPNSTSNPSKHTSAYASYNKGKNSKWSSPFASTTKKPQESSEKYSKKSSTRKKEHFNKKPSFPRDTEYSHIYNMKYDPRSGIGIRVKRQEPESLKKENNNSDYLPKSAMKQKKGGPKDSSKHPSNDGKIPESKPSVYKSRASNLFSSNEQSIHSSFGSKFHFDKSSNPFSFEFSPSSNAAKPSNSEECNIPKFNSSFKTSNDFFTFTKTEESSPYSFSFKLEDSNTPKFKSSSKPVKSSFVFTKPEAESSNPFSFDFGSSGPKSRSDTRNNIRTPLWTSSVFEKPESDLPNKTAFGFMRSNTSTFNQKCDDFSSASFMKEKTEFEEQLQEDNDHSLGDLFSKINISTESPSVAMPSIPVIQPPSFPIFSSIDFNVRNREYWNQLMVFQKLYSKYCTESQHFINSWINIKKELHIVPVNWEIFEKVEKSWDQCEEFVAEFRQTEEKYFLFLKRLRELINKNQML
What is the function of this protein?
Has a role in sporulation.
What are the official names of this protein?
Meiotically up-regulated gene 184 protein.
Protein: DYR_STAAN
Sequence: MTLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLFEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRKK
What is the function of this protein?
Key enzyme in folate metabolism.  Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
What are the official names of this protein?
Dihydrofolate reductase, DHFR.
What is the protein family that this protein belongs to?
Belongs to the dihydrofolate reductase family.