PharMolix/UniProtQA huggingface dataset:
Protein: FLGH_BURMA
Sequence: MRRPGAAALAAAALALAGCAQIPREPITQQPMSAMPPMPPAMQAPGSIYNPGYAGRPLFEDQRPRNVGDILTIVIAENINATKSSGANTNRQGNTSFDVPTAGFLGGLFNKANLSAQGANKFAATGGASAANTFNGTITVTVTNVLPNGNLVVSGEKQMLINQGNEFVRFSGIVNPNTISGQNSVYSTQVADARIEYSAKGYINEAETMGWLQRFFLNIAPW
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: EFTU_STAHJ
Sequence: MAKEKFDRSKEHANIGTIGHVDHGKTTLTAAIATVLAKNGDTVAQSYDMIDNAPEEKERGITINTAHIEYQTDKRHYAHVDCPGHADYVKNMITGAAQMDGGILVVSAADGPMPQTREHILLSRNVGVPALVVFLNKVDMVDDEELLELVEMEVRDLLSEYDFPGDDVPVIAGSALKALEGDAQYEEKILELMQAVDDYIPTPERDSDKPFMMPVEDVFSITGRGTVATGRVERGQIKVGEEVEIIGIHDTSKTTVTGVEMFRKLLDYAEAGDNIGALLRGVAREDVQRGQVLAAPGSITPHTKFKADVYVLSKDEGGRHTPFFTNYRPQFYFRTTDVTGVVNLPEGTEMVMPGDNVEMTVELIAPIAIEDGTRFSIREGGRTVGSGVVTEIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTCH1_MOUSE
Sequence: MGASDPEVAPWAPGGAAGMAGAGAGAGARGGAPAGVEARARDPPPAHRAHPRHPRPAAQPSARRMDGGPGAPGSGDNAPTTEALFVALGAGVTALSHPLLYVKLLIQVGHEPMPPTLGTNVLGRKVLYLPSFFTYAKYIVQVDGKIGLFRGLSPRLMSNALSTVTRGSMKKVFPPDEMEQVSNKDDMKTSLKKVVKETSYEMMMQCVSRMLAHPLHVISMRCMVQFVGREAKYSGVLSSIGKIFKEEGLLGFFVGLIPHLLGDVVFLWGCNLLAHFINAYLVDDSVSDTPGGLGNDQNPGSQFSQALAIRSYTKFVMGIAVSMLTYPFLLVGDLMAVNNCGLRAGLPPYSPVFKSWIHCWKYLSVQGQLFRGSSLLFRRVSSGSCFALE
What is the function of this protein?
Protein insertase that mediates insertion of transmembrane proteins into the mitochondrial outer membrane (By similarity).  Catalyzes insertion of proteins with alpha-helical transmembrane regions, such as signal-anchored, tail-anchored and multi-pass membrane proteins.  Does not mediate insertion of beta-barrel transmembrane proteins (By similarity).  May play a role in apoptosis (By similarity).
What are the official names of this protein?
Mitochondrial carrier homolog 1, Mitochondrial carrier-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein.
Protein: CAR16_HUMAN
Sequence: MADKVLKEKRKLFIHSMGEGTINGLLDELLQTRVLNQEEMEKVKRENATVMDKTRALIDSVIPKGAQACQICITYICEEDSYLAETLGLSAALQAVQDNPAMPTCSSPEGRIKLCFLEDAQRIWKQKLQRCHVQNTIIKWSERYTSGSFEMQWLFLRTNFIERFWRNILLLPLHKGSLYPRIPGLGKELQTGTHKLS
What is the function of this protein?
Caspase inhibitor.  Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation.  Inhibits the release of IL1B in response to LPS in monocytes.  Also induces NF-kappa-B activation during the pro-inflammatory cytokine response.  Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death.  Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.
What are the official names of this protein?
Caspase recruitment domain-containing protein 16, Caspase recruitment domain-only protein 1, CARD-only protein 1, Caspase-1 inhibitor COP, Pseudo interleukin-1 beta converting enzyme, Pseudo-ICE, Pseudo-IL1B-converting enzyme.
Protein: HAT2_ASHGO
Sequence: MTTKLKGLKELGNTSDPLRTVSYQVRTKMSDYEDDNTDVQSLTVEEEYELWNSNVPVMYEFVSETKLTWPSLTIQWLPSDGQSPEQSLIFGTHTAGEEVNYLKVATINLPAGIAGLDQGDEEDEANDHSSFAIANKFPHIEEVIRARYMPANSNIIATINGKGTISIFDRTLEESKAQVSTLAFHKENGYGLAFNPHISGELLSGSDDTTVALWDIEAAKKPKSILTSHDDIVNDVKWHEFESNVFGTVSEDKTLQVHDKRVRLEPVKKLPTASPFNTLSFSKHSRNLLAAAGVDSQIYLYDMRDMSSPLHVMSGHQDSVTTVEFSPHTDGIICSSGSDRRAIIWDLTQIGAEQSQDDADDGAPELMMMHAGHRSPVNEFSFNPQIPWLLASTEEDNVIQAWKVSMKLVNASPPAISDPSLLV
What is the function of this protein?
Regulatory subunit of the histone acetylase B (HAT-B) complex.  The complex acetylates 'Lys-12' of histone H4 which is required for telomeric silencing.
What are the official names of this protein?
Histone acetyltransferase type B subunit 2.
What is the protein family that this protein belongs to?
Belongs to the WD repeat RBAP46/RBAP48/MSI1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL9_BACFR
Sequence: MEIILKEDVVNLGYKNDIVTVKSGYGRNYLIPTGKAVIASPSAKKMLAEELKQRAHKLEKIKKDAEAVAAKLEGVSLTIATKVSSTGTIFGSVGNIQIAEELAKLGHEIDRKIIVVKDAVKEVGAYKAIVKLHKEVSVEIPFEVVAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: PANB_DEIDV
Sequence: MKRSIPELLQSEQPLVMVTAYDYPGGLHAEAAGVDMILVGDSLGNVVLGYESTAPVTLSDMIHHSKAVRRGAPQTFLVVDMPFGTYHTGVTDAMRNAVRIIQETGADAVKMEGSTPEVLQVVDTLSRNGVPVVGHVGLMPQTATAQGGLRVQGKDDDTARRTLEGALALEAAGAFCVVLEAIPARLAKLITDRLQVPTVGIGAGINCDGQVLVTHDLLGIYEGEEKKIAKRYAEVGRVSREAIARYADEVRRREFPTRENSFVMKDDVLDKLY
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEPF_THEFY
Sequence: MAGALRKMAVYLGLVEDDRYDHRYADEYDDFEDFDEPLDERPSRNRSPRDDSRNNAVTDSSDHSPSRNERRSPAPAPATADLARITTLHPRTYNEARTIGEHFREGIPVIMNLTEMVDSDAKRLVDFAAGLIFGLHGSIERVTNKVFLLSPANVEVTAEDKARIAERGFFNQS
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: RECO_STRP3
Sequence: MQLTESLGIVLFNRNYREDDKLVKIFTEVAGKQMFFVKHISRSKMSSIIQPLTIADFIFKLNDTGLSYVVDYSNVNTYRYINNDIFRLAYASYVLALADAAIADNESDSHLFTFLKKTLDLMEEGLDYEILTNIFEIQILDRFGISLNFHECAICHRTDLPLDFSHRFSAVLCSEHYYKDNRRNHLDPNVIYLLSRFQKITFDDLRTISLNKDIKKKLRQFIDELYHDYVGIKLKSKTFIDNLVKWGDIMK
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: GATA_MYCTU
Sequence: MTDIIRSDAATLAAKIAIKEVSSAEITRACLDQIEATDETYHAFLHVAADEALAAAAAIDKQVAAGEPLPSALAGVPLALKDVFTTSDMPTTCGSKILEGWRSPYDATLTARLRAAGIPILGKTNMDEFAMGSSTENSAYGPTRNPWNLDRVPGGSGGGSAAALAAFQAPLAIGSDTGGSIRQPAALTATVGVKPTYGTVSRYGLVACASSLDQGGPCARTVLDTALLHQVIAGHDPRDSTSVDAEVPDVVGAARAGAVGDLRGVRVGVVRQLHGGEGYQPGVLASFEAAVEQLTALGAEVSEVDCPHFDHALAAYYLILPSEVSSNLARFDAMRYGLRVGDDGTRSAEEVMAMTRAAGFGPEVKRRIMIGTYALSAGYYDAYYNQAQKVRTLIARDLDAAYRSVDVLVSPTTPTTAFRLGEKVDDPLAMYLFDLCTLPLNLAGHCGMSVPSGLSPDDGLPVGLQIMAPALADDRLYRVGAAYEAARGPLLSAI
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: RL30_THEAB
Sequence: MKKLKITLVKSPIGYKYDQKDTVKRLGLRKLNSTVIKDDVPQIRGMIRKVRHLVKVEEIEE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: NDUS8_PONPY
Sequence: MRCLTTPMLLRALAQAARAGPPGGRSLHSSAVAATYKYVNMQDPEMDMKSVTDRAARTLLWTELFRGLGMTLSYLFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAICPAQAITIEAEPRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEELLYNKEKLLNNGDKWEAEIAANIQADYLYR
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor (By similarity).  Essential for the catalytic activity and assembly of complex I (By similarity).
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial, Complex I-23kD, CI-23kD, NADH-ubiquinone oxidoreductase 23 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: RS11_METHJ
Sequence: MSEGKEKWGVAHIYASFNNTIITVTDLTGAETITKSSGGMVVKQDRNESSPYAAMQMAGNVAQAAREKGIVGLHVKVRAPGRGKQRSPGPGAQAAIRALARAGMRIGLIEDVTPVPHDSIRPKGGRRGRRV
What is the function of this protein?
Located on the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: ASTA_ASPOR
Sequence: MDLEPWGPLYRKQDQDGSLDNIAVVSGDIPSPHPKNEPSQTSTLHIPRDSDLDSDIPSVPTALIIAWGLTLSSLTGDEVVGFDLLPFRGDYQDLGARPYHFLLKFGYREWSREAATTGMDLGSASSEGLPQGMGNRPQIAPSRFRNVLIIKQCSDAPGDSGSLESPSLGNVDKDEPTDAFRADMFISIQCGIGRTGIDVHCSFDPAFWTSENIRMILLDLSRNFKEVMRCGRDDTPLTCLEGMSPKGLDCVLRRNIIPPPPKMEACVHHRFQARCRQNPSALAIDAWDGQLTYAELDSLSSQLASRLVSSITICPRGFMGVLMEKSAWVPVAILAVLKVGSAFVFLDGSQPLQRLKIICAETKSQLVLSSAHYREKANTLGPPVLLVEKNQSGLGQAKENDSCPSLLEDYPQPQSQPQDTLYAVFTSGSTGEPKGAMVDHGAFCTMCGPQMAARPTTNVSPRVFQFAPHAFTVSILDYLGTLLQGGCVCVPSEEELRNNMAGAIEGLSANIVTMTPSMARVLDPTQTPSLQLVLLAGEMMAQCDLDKWSQCVRLLSLYGQSENAAGSMISEKSIVPRAPNTFETLTPGFQCWIVSQDNPHRLMALGEVGELLLEGPALGQGYMNDPIQTEDKFICRSFCLEYAHSGSPQSYRLFKTGDLVRYTPAGEIELLGRKGAEVKLRGQRIDLTEIEHHLRCLFPSATRVVADVIIPSDDIDGLHPVLAAFVQVDSVSRTGQSAEATFASPRPEFRAEAKAVLSGLCQTIPSYMIPMTIIPTEAFPFTATGKLDRRSLRQYASAMSRSDLLKYVTDDRGPVVTAVTPVEIIIHDACVEALGVSSDKVGMLDSFPDLGGDSLAARRMVSICRTKGLELAVADILAHSSLTSLAEKCSAGGGGAKQISQGVEMLDPFSTAKEEFLSHLPSFLPNADMIADVFPVQGAQRRAARAIDTFIFRLSGPVDADRLRDACQVLQQAHLALRSIFVPFYGKFMQVVLRVPPLDFTRRLLPDGTDLVKWAESIGQADKTQRPPSEEFVVRFTLAETAGTPDYSIFMMRLSHAQYDAGCLARIISDLWAVYEQKQLVVKSDFAQYARRAVQQTHLLSMEAFWRDLLAGTTGLTPLPVTGISAEEERTIIVQQRVELKEPPPTGISMATVVRGAWSWVLHQQTGNTVVVFNEMLNGRDVVPLEDTEPVVGACHSIVPVCVHFPLPQSGRTPRELLSALQEQHLASLTFTTLDRDYLIQNCTEWTSHQSGFILAYQNFPEICDLVIGEDLSCQWASQVLDLAEPGEAWVTATPLPGALQISLRVSTAAMDEQEANAWISALGQTIIRFLDSPDSVL
What is the function of this protein?
Nonribosomal peptide synthetase; part of the gene cluster that mediates the biosynthesis of astellolides, drimane-type sesquiterpene esters that show antimicrobial, anti-inflammatory, and anti-tumor activities (PubMed:27628599).  The first step in astellolide biosynthesis is performed by the sesquiterpene cyclase astC that catalyzes the formation of drimanyl pyrophosphate from farnesyl pyrophosphate (PubMed:27628599).  Drimanyl pyrophosphate is then dephosphorylated by the sesquiterpene phosphatase astI to produce drimanyl monophosphate which is further dephosphorylated to drim-8-ene-11-ol by atsK (PubMed:27628599).  Drim-8-ene-11-ol is converted to confertifolin, probably by the cytochrome P450 monooxygenase astD and/or the dehydrogenase astE (PubMed:27628599).  The cytochrome P450 monooxygenases astB, astF and astJ then hydroxylate confertifolin at C6, C14, or C15 to form trihydroxy confertifolin (PubMed:27628599).  The nonribosomal peptide synthetase astA catalyzes ester bond formation between trihydroxy contifolin and benzoic acid (BA) or 4-hydroxy benzoic acid (4HBA), leading to the formation of dideacetyl astellolides A and B, respectively (PubMed:27628599).  Finally, the O-acetyltransferase astG converts dideacetyl astellolides A and B into deacetyl astellolides A and B (PubMed:27628599).
What are the official names of this protein?
Nonribosomal peptide synthetase astA, Astellolide biosynthesis cluster protein A.
What is the protein family that this protein belongs to?
Belongs to the NRP synthetase family.
Protein: SIDA_CERS8
Sequence: MEAQDPLFDLIGLGFGPANLAIAGAIVEKWEGPSAGGDGGISAHKVLFIEKQPEFQWHPGMLLPNTRMQISFLKDLATLRSPQSPLTFLSYLHAEGRLLPFINRGSFTPTRREYFDYLSWAARTVESKGIKVQYGEEVVSIRGSEDNTVEVHSRDVKTGTIVIRRTRNLVISPGGNPKLPPNISLLYPHPRILHSSRYATSVDQLLGTLSPANRPLRIAVIGSGQSAAEVTLDLHSRLSSMPGGDRPHAIDMIFRNGSLKPSDDSPFSNEIFDPDTTEVIYNLPTQSDRENILKEYNNTNYSVVNPRTIDAMYEVMYDQKLDDAIARRKGDKATPSAARITMHPHMTLYFADDLPQLAETDSATETSQEGIRLTLQNVFSQAQSTRDYDAVVCATGYDRTSWLRMLTSSDIGKHFGLNLSSDPVQLVPSTEIPKGPDGSLFDASEEEATWRPASPITPASPSPPSTPTSSALSQSRMLGQLPITKLYITREYCLVPNSPQFKPRIYLQGCTEATHGLSESLLSILGVRAGLVVDDLWKNSQ
What is the function of this protein?
L-ornithine N(5)-monooxygenase; part of the siderophore basidioferrin biosynthetic pathway (PubMed:28842536).  The biosynthesis of basidioferrin depends on the hydroxylation of ornithine to N(5)-hydroxyornithine, catalyzed by the monooxygenase SMO1 (PubMed:28842536).  The second step, the acylation of N(5)-hydroxy-L-ornithine is catalyzed by a not yet identified N-acyltransferase (PubMed:22434909).  Finally, assembly of basidioferrin is catalyzed by the nonribosomal peptide synthase (NRPS) NPS2 via amide bond formation between three L-AHO molecules to release the linear L-AHO trimer (PubMed:22434909).
What are the official names of this protein?
L-ornithine N(5)-monooxygenase, Basidioferrin biosynthesis protein SMO1, L-ornithine N(5)-oxygenase, Siderophore biosynthesis protein SMO1.
What is the protein family that this protein belongs to?
Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.
Protein: RNH_RICAH
Sequence: MNSKVVIYTDGACAGNPGPGGWGALLKFNDASKEIFGYELDTTNNRMEITAAFEALKILKKSCNVEIYTDSKYLQQGITAWIHNWIKNNWCKSNNEPVKNADLWQKLYAELSKHTIIWKWVKGHANNSGNIAADKLAVQGRETAIEVLKCRG
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSPA_BACC4
Sequence: MLHRYLPMTEEDKKEMLQTIGVQTIDELFSDIPESVRFKGDLKIKEAKSEPELLKELSQMASKNANLKEYASFLGAGVYDHYAPVIVDHVISRSEFYTAYTPYQPEISQGELQAIFEFQTMICELTGMDVANSSMYDGGTALAEAAMLAAGHTRKKKILVSSAVHPESRAVLETYAKGQNLEVVEINHKDGVTDLDVLQSEVDDTVACVIVQYPNFFGQVEKLADIEKIVHQQKSLFIVSSNPLSLGALTPPGKFGADIVIGDAQPFGIPTQFGGPHCGYFATTKAFMRKIPGRLVGQTVDSDGKRGFVLTLQAREQHIRRDKATSNICSNQALNALAASVAMTALGKQGVKEMARQNISKAQYAKRQFEAKGFTVTFAGPFFNEFVVDCKRPVKEVNDALLQKNIIGGYDLGRDYKEHENHMLVAVTELRTKEEIDTLVNEMGAIQ
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: UXS6_ARATH
Sequence: MASNSSNGTTTTKPPPMPSPLRNSKFFQSNMRILVTGGAGFIGSHLVDKLMQNEKNEVIVADNYFTGSKDNLKKWIGHPRFELIRHDVTEPLFVEVDQIYHLACPASPIFYKYNPVKTIKTNVIGTLNMLGLAKRVGARILLTSTSEVYGDPLVHPQTESYWGNVNPIGVRSCYDEGKRVAETLMFDYHRQHGIEIRIARIFNTYGPRMNIDDGRVVSNFIAQALRGEALTVQKPGTQTRSFCYVSDMVEGLMRLMEGDQTGPINIGNPGEFTMVELAETVKELIKPDVEIKMVENTPDDPRQRKPDISKAKEVLGWEPKVKLREGLPLMEEDFRLRLGVPKK
What is the function of this protein?
Catalyzes the NAD-dependent decarboxylation of UDP-glucuronic acid to UDP-xylose.  Necessary for the biosynthesis of the core tetrasaccharide in glycosaminoglycan biosynthesis (By similarity).
What are the official names of this protein?
UDP-glucuronic acid decarboxylase 6, UDP-XYL synthase 6, UDP-glucuronate decarboxylase 6, UGD, UXS-6.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZAPB_YERPG
Sequence: MSFEVFEKLEVKVQQAIDTITLLQMEIEELKEKNNTLTQEVQDAAGSREALVRENEQLKQEQHVWQDRLRALLGKMEEV
What is the function of this protein?
Non-essential, abundant cell division factor that is required for proper Z-ring formation.  It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle.  Its recruitment to the Z-ring requires functional FtsA or ZipA.
What are the official names of this protein?
Cell division protein ZapB.
What is the protein family that this protein belongs to?
Belongs to the ZapB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the septum at mid-cell, in a FtsZ-like pattern.
Protein: Y065_AFV2P
Sequence: MRFSNCFNKFKFCIGTEKKYSFPICTSTYTSFSLFACIWSIFIHISLNKSFIYQKSWYYSFFQNR
What are the official names of this protein?
Uncharacterized protein ORF65.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: COXX_SULIN
Sequence: MSLQQKIKAYLKLGKLGVVSLLDLAAVAGAFLAYKHGISLLPIIPMFIGGTLASMGAMIINSGIEIDRDKVMSRTSKRPTVVGYVNRKEAIIVGSLLAILGTALGFIDNILTAFFIALGVVIYIFVYTILLKPRTWLNIVIGGFAGSAAAWAGYTSLTNSLTLEGFLLGFLIFMWTPGHFWSLALKYREDYVNAHYPMLPAVVGITTSARAIAISNALMIPIVLLLGYYINLIALIAFSILSLFLMFLSYRLILNPTKEEAIKSFIFSNIYLMLILLIMIIVKLI
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LYSY_PYRCJ
Sequence: MKRVCIVGASGFTGGELLRILLQHSGVEVVCATSRKFKGEYVYRVHPNLRGFTQLKFVEPTIDAALKADVVFLALPHGESVKWVPQLYESGVAVFDLSADFRLKDPNAYVEWYKWPQPHPYPDLLAKAVYGQPELHREELVGARLVAVPGCMATASILMLAPLAKFGLISAPPVVDAKIGSSGAGAEGSVVDLHSFRTYVVRPYEPVHHRHIAEIEQELSRLAGKEVKVAFTPHAVDIVRGIFTTGHVFVEKMPTEADLWKYYRALFGDSKFIRIVKDRLGISRYPNVKYVLGSNLVDLGFELDARMKRVVTFAAIDNLVRGAAGQAVQAFNIAMGFPEDEGLRHIPVAPI
What is the function of this protein?
Involved in both the arginine and lysine biosynthetic pathways.
What are the official names of this protein?
Putative [LysW]-L-2-aminoadipate/[LysW]-L-glutamate phosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_DEHMB
Sequence: MIAIYPGRFDPVTLGHLSVARRASGFCDRLIIAVFDNPAKPGLFTAAERVDFIKQSIKDLPNVEVRSFSGLMVNFARKMGASLIIRGLRVGADFEREMEMYVMNRRLDEGIELCCLFSEPQYQYLSASLIKEIVILGGDSSGLISEHVAVALKNKLASV
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DMLA_ECOLI
Sequence: MMKTMRIAAIPGDGIGKEVLPEGIRVLQAAAERWGFALSFEQMEWASCEYYSHHGKMMPDDWHEQLSRFDAIYFGAVGWPDTVPDHISLWGSLLKFRREFDQYVNLRPVRLFPGVPCPLAGKQPGDIDFYVVRENTEGEYSSLGGRVNEGTEHEVVIQESVFTRRGVDRILRYAFELAQSRPRKTLTSATKSNGLAISMPYWDERVEAMAENYPEIRWDKQHIDILCARFVMQPERFDVVVASNLFGDILSDLGPACTGTIGIAPSANLNPERTFPSLFEPVHGSAPDIYGKNIANPIATIWAGAMMLDFLGNGDERFQQAHNGILAAIEEVIAHGPKTPDMKGNATTPQVADAICKIILR
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidative decarboxylation of D-malate into pyruvate.  Is essential for aerobic growth on D-malate as the sole carbon source.  But is not required for anaerobic D-malate utilization, although DmlA is expressed and active in those conditions.  Appears to be not able to use L-tartrate as a substrate for dehydrogenation instead of D-malate.
What are the official names of this protein?
D-malate dehydrogenase [decarboxylating], D-malate degradation protein A, D-malate oxidase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLO_STAAR
Sequence: MTHDYIVKALAFDGEIRAYAALTTETVQEAQTRHYTWPTASAAMGRTMTATAMMGAMLKGDQKLTVTVDGQGPIGRIIADANAKGEVRAYVDHPQTHFPLNEQGKLDVRRAVGTNGSIMVVKDVGMKDYFSGASPIVSGELGEDFTYYYATSEQTPSSVGLGVLVNPDNTIKAAGGFIIQVMPGAKDETISKLEKAISEMTPVSKLIEQGLTPEGLLNEILGEDHVQILEKMPVQFECNCSHEKFLNAIKGLGEAEIQNMIKEDHGAEAVCHFCGNKYKYTEEELNVLLESLA
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADD_BORAP
Sequence: MRIAILGGTYNPVHIGHIFLAKEIEYLLNIDKIIFIPTCNPTHKLIGEGVSVKNRIDMLKLALKNENKMFIDDCDIINGGITYTIDTISCVKKKYKNDKLFLVIGDDLFQNFDSWKDPQSIASSVDLVVAHRIYKERLKSSFKHIYIDNKIIPISSSEIRNRIANGFPVSYLLPFGVLKYIKDNNLYVKKVNV
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: RSME_SYNY3
Sequence: MLAKAFAGSKSHKILINAWFTTLPGQCQKPIVQFVLSPILVSTNLTPSILSLPVQEKSSSSFVMAYRLVVAPEQIIEATVTLTTAQLHYLQRVLRLQKGDGFMVLDGGGGVWRAQLNDLAHGTAQLLETVSEQNELPLPVTLAIALPKGSGFEEIIRPCTELGATAFQPLLTERTLLKPSQNKLERWQRIVTEAAEQSERQWLPPVAAPLTFGQFVEKVAGPETLALLCVTRLNSPMLGAYLKQSNLPAQIVLATGPEGGWTDNEISLAIAKGFQPVSLGKRILRAVTAPTVALAQINALLES
What is the function of this protein?
Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA.  Acts on the fully assembled 30S ribosomal subunit (By similarity).
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase E, 16S rRNA m3U1498 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RsmE family.
What are the subcellular locations of this protein?
Cytoplasm.