PharMolix/UniProtQA huggingface dataset:
Protein: PUR7_ACIB3
Sequence: MLKQTLLYTGKAKSVYETDNADHLILVFRDDASAFNGEKIEQLDRKGKVNNRFNAFIMEKLAEAGIETHFEKLLSPTEVLVKKLQMIPVECVIRNYAAGSLCRRLGVEEGKELTPPTFELFYKDDGLGDPMVNESQAIALGWATAEQLEQMKVLTYKVNDVLKALFAEGNMILVDFKLEFGVFHDRIVLGDEFSPDGCRLWDKDTKKKLDKDRFRQGLGGVVEAYEEVAARLGVDLSDI
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: SYC_CAUSK
Sequence: MTLKLYDTMAREKRDFVPADPGRVTMYVCGPTVYNHAHIGNFRPVVVFDVLFRLLRHVYGEDAVVYARNVTDVDDKINAKATAEGVEIKVITDRYLAAYHEDAAALLTLPPSLEPKATEHMGPIIEMIGELVANGSAYAAEGHVLFDTQAFPDYGQLSGRDLDDMIAGARVEVAPYKRHPADFVLWKPSKENEPEWDSPWGAGRPGWHIECSAMIDKTLGQTIDIHGGGIDLAFPHHENELAQSRCAHGAPVLANYWLHNGFLDMAGEKMSKSLGNVIIPHELLKTTPGEAIRWALLSGHYRQPLDWTPELIEQSKKALDRLYGALRRAKTVEAGESEPSDEVMAALSDDLNTPLAVSGFFELSSAIERAVTAGDELAITANKGRLLASAGLLGFLQADPDSWFEGDADDDLKAKVEDLLARRIAARTAKDWTAADAIRAEIDALGVVVMDGPAGATWRMKD
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VE1_HPV20
Sequence: MADPKGSTSKDGLDDWCIVEAECSDVDNDLEELFDRDTDSDISELLDDNDLEQGNSRELFHQQECKDSEEQLQKLKRKYISPKAIAQLSPRLESISLSPQQKSKRRLFAEQDSGLELTLTNEAEDVSSEVEEVPALDSQPVAEGHLGTVDIHYTELLRASNHKAILLAKFKEAFGIGFNDLTRQFKSYKTCCNDWVLSVYAVHEDLLESSKQLLQQHCDYIWIRGIAAMSLFLLCFKAGKNRGTVHKLMTSMLNVHEKQILSEPPKLRNVAAALFWYKGAMGSGAFSHGPYPNWMAQQTIVGHQSTEASAFDLSEMIQWAFDHNYLDEADIAFQYAKLAPENSNAVAWLAHNNQARFVRECASMVRFYKKGQMKEMSMSEWIYARINEVEGEGHWSSIAKFLRYQQVNVIMFLAALKDMLHSVPKHNCILIHGPPNTGKSAFTMSLIHVLKGRVLSFVNSKSQFWLQPMSETKIALIDDVTDPCWVYMDTYLRNGLDGHYVSLDCKHKAPIQTKFPALLLTSNINVHNEVNYRYLHSRIKGFEFPNPFPMKPDNTPEFELTDQSWKSFFTRLWKQLELSDQEDEGENGESQQAFQCSARSANEHL
What is the function of this protein?
ATP-dependent DNA helicase required for initiation of viral DNA replication.  It forms a complex with the viral E2 protein.  The E1-E2 complex binds to the replication origin which contains binding sites for both proteins.  During the initial step, a dimer of E1 interacts with a dimer of protein E2 leading to a complex that binds the viral origin of replication with high specificity.  Then, a second dimer of E1 displaces the E2 dimer in an ATP-dependent manner to form the E1 tetramer.  Following this, two E1 monomers are added to each half of the site, which results in the formation of two E1 trimers on the viral ori.  Subsequently, two hexamers will be created.  The double hexamer acts as a bi-directional helicase machinery and unwinds the viral DNA and then recruits the host DNA polymerase to start replication.
What are the official names of this protein?
Replication protein E1, ATP-dependent helicase E1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E1 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: CRG2_XENLA
Sequence: MERIFFYEDRNFQGRCYECSSECSDLSSYFNRCNSIRVENGNWILYEQPSYRGHQYYLWKGEYPDFQRWMGFNEYIKSCRFIPNHHGQYKMRIYERGDFQGKMMEFSDDCPNTYDRFSFRDIHSCNVSEGHWMFYEEPNYRGRQYYLRPGEYRKFSDWGASTARIGSFRRVHHMF
What is the function of this protein?
Crystallins are the dominant structural components of the vertebrate eye lens.
What are the official names of this protein?
Gamma-crystallin-2, Gamma-2-CRY, Gamma-crystallin II.
What is the protein family that this protein belongs to?
Belongs to the beta/gamma-crystallin family.
Protein: ACP_MYXXA
Sequence: MASKEEILAGLAEIVNEETGLDTAEVQPEKSFTDDLDIDSISMMTIVVNAEDKFGVKIPDEEVKNLKTVQDAVDFIXGA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KUP1_POLSJ
Sequence: MRVRRQCSPVLHRSLSMNQISQRQGVAALTLGAIGVVYGDIGTSPLYTMKEIFSPATGIPLDATHLIGAVSVIFWGLMMIVTLKYVVLILRASNRGEGGIMALTALAAHAAGKTPGRRTALLLTGVLGAALFYGDSVITPAISVLSAVEGLEVVAPGLKPYVLPVSLAVLVGLFMVQRHGTGVVGKLFGPVIVLWFAVLAFTGVVQILQQPAILAALNPLRAVAFLHAQGWHLFVAVGAIVLAFTGVEALYADMGHFGKRPIQLAWMGLVLPALALNYMGQGALLMRDPSALENPFYRLFPQAWLIPAVILATCATVIASQAVISGAYSMTKQAVQLGLLPRMQVQYTSAREAGQIYMPEVNWILLAAVLLAVVGFGSSSALAAAYGIAVTMTMLITTVLTFFVVRHGWGYPLPVALAATGVFLALDTVLVIACSLKFWQGGWFPLVLGVVLFILMATWKRGRELLIENIRNNDPELLPFISSLAKDSMHRTPRTAVYAVANPDTVPQALLHNLKHNQVIHERNLILTVVFHEVPWIPFEERVQVTPLVPGFWKVQVNYGFKNTPDVPQALELCRDQGLALNLFETSYFLSRETIVPTKGAGMTHWREALFAAMSRNAGSVVGFLRLPNNSVIELGTRVQI
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup 1.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS15_CYAP4
Sequence: MALLQQRKQEIISGYQTHETDTGSADVQVAMLTERINKLSTHLQANSKDHSSRRGLLQMIGRRKRLLAYILKHNPERYRALITRLGIRG
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: HSP1_THYST
Sequence: MARYRHSRSRSRSRYRRRRRRRSRYRSRRRRYRGRRRRRSRRGRRRRGYSCRRYSRRRRRRY
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Sperm protamine P1.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: VENT1_XENTR
Sequence: MVQQGFSIDLILARNREEAPDGKDSVSSRPHIPCAPQPLAPTKYAKEIPRRKDGQEQGEITSFQCSSEEARNRQFSNPSLPALHRSSGSSDEFSPAGSEDDGTESSGRNSQENDTEHRSKSPKSDLQRRLRTAFTPQQITRLEQAFNKQRYLGASERKKLATSLQLSEIQVKTWFQNRRMKLKRQIQDQQHSMVPPPVCYPQTFSYYPGGFPVPLNSGSFYQPPAHPFQAPQHSFIPQPLHHHMRMSAHQEQFPPLFGAQYM
What is the function of this protein?
Transcriptional repressor.  Cooperates with vent2 in a ventral signaling pathway downstream of bmp4, which antagonizes the Spemann organizer and dorsal mesoderm formation, and leads to ventral mesoderm formation.  Acts downstream of bmp4 to repress transcription of foxa4-B/XFD-1'.  Binds to DNA with preference for the target sequence 5'-CTATT[T/C]G-3'.  Also binds 5'-TGCATTTTG-3' at a lower frequency, and occasionally 5'-TTGATC-3'.  Binds to the homeobox 2 (HBX2) repressor element in the promoter of the myf5 gene (By similarity).  Cooperates with vent2 to repress myf5 expression in the ventral domain.
What are the official names of this protein?
Homeobox protein vent1, Vent-1.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1263_RICBR
Sequence: MQSSLIKILGVLAIVATLVCFVFAALGMIGAVSVGNGCYMRYAPGGKGGSDSITSTITLNANANYVNTSTMLPDGTMQLTPDPAHYGEWLNTQVEVKDKQAVSLQVVGQISLCLAYVPKDNLQFTESTRPGKSNLDDNGKMIPIPRVTDVNKPPLSLIMDAKNNEWRNITEMYANDRILVSVTPNYSPGAGGTVGAMDAFKGTNVTADCSQGKTAYDPICGRYSIYSGPYVNACELKQNYWQGNKKQKCPNGCVWGTIDWCYTAPSAWCTYYYVCDSLSAWVNNYGTMPEPYKDDGTFTFSWASNSGGIFIDYANLQCSNNINIPPNGKCPDSVDDRSPKDKDYIGGAGCTSGVCNGGEFQSQRRFWYTSDGNGGKGPTGLIWQISNTSNVDSTLPSTLQFAQFVTASDQPTEYGNEYKVIYNIPFNSNTDKGYLQYRLWCPTSQDASKNTGGYVMNIKQTKCYRENGNSLTDVFNNRGQVQYLVVPSAENPNTSGKNYSPEAAIVDSKGKANFNAAGEGYIWMRVLNDPNDYKDSEGSYKVHFSTSQSVGSFTIKVMNPLLQLFKGKVKGAAESIFRNIVCYGGDTSSCTNFFNYIKALLILYVMVYGAMFLLGFAKINQKDLVVRIVKIGIVSGLMNGNTFEFFNNYLFDTIANFSDEIISNMSGYSLFNSNGTVSNPFMFLDAVMSRILFSQTFMAQLLALLSLGLSGIIYFIITVIAVMIVIITAFRAAAVYIMAFMATCILIGIAPIFISFLLFDFTRYLFDNWVRFTIRYMIEPVVLMAGIIVLTQLFTIYLDFVLGYSVCWKCALPIKIPFIGTILPVALLNVPIFCINWFAPWGMDYMSGMMGVNMQNIVALVIIAYGMYGYVEFSGNMVARLTSAAGPSATSMGGAMSGAAEQGALSQVGMDEKTRKGITGRAKERLKQRNETLKQAEKTRKNAPKEEPPKAEIPK
What are the official names of this protein?
Uncharacterized protein RBE_1263.
What is the protein family that this protein belongs to?
Belongs to the TrbL/VirB6 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GCSPA_EXIS2
Sequence: MDFRYLPMTQEDEKEMLQTIGADSIEDLLADIPASVRDQGTLEEVGIPLPETDLIRTLSKLADQNMNTKQYPSFLGAGIYDHYAPAVVNHMLLRSEFYTAYTPYQPEISQGELQAIFEYQTMICELTGMDVANSSMYDGITALAEAAMLACAHKKKKTIVLSDGVHPEAHDVVRTYANGPGLEVETLPLVNGETAIANLDALEDVACVIVQYPNFYGRVEDLQALADATHAKGGLFIVSANPLALGLLEAPGKLGADITIGDCQPFGIPQSFGGPTCGYFTTTKALMRKIPGRLVGQTVDEDGKRGFVLTLQAREQHIRRDKATSNICSNQALNALAASIAMSALGKRGIRELATRNLQTAYALKKSLIQAGFHIVDDGPSFNEFVVELPIDATEAGKQLLQAGIIGGLPLGTFDESRSNQMLVCATELRTKEELDQFVTALGGLTHA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: RR12_SOYBN
Sequence: MPTMKQLIRNTRQPIRNVTKSPALRGCPQRRGTCTRVYTITPKKPNSALRKVARVRLTSGFEITAYIPGIGHNLQEHSVVLVRGGRVKDLPGVRYHIVRGTLDAVGVKDRQQGRSKYGAKKPK
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits (By similarity).
What are the official names of this protein?
30S ribosomal protein S12, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NGF_PIG
Sequence: LIGIQAEPHTESNVPAGHAIPQAHWTKLQHSLDTALRRAHSAPAGANSARVAGQTRNITVDPKLFKKRRLRSPRVLFSTQPPPVAADTQDPDLEASGAASFNRTHRSKRSSSHPVFHRGEFSVCDSVSVWVGDKTTATDIKGKEVMVLGEVNINNSVFKQYFFETKCRDPNPVDSGCRGIDSKHWNSYCTTTHTFVKALTMDGKQAAWRFIRIDTACVCVLSRKAGRRA
What is the function of this protein?
Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems.  Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival (By similarity).  The immature NGF precursor (proNGF) functions as ligand for the heterodimeric receptor formed by SORCS2 and NGFR, and activates cellular signaling cascades that lead to inactivation of RAC1 and/or RAC2, reorganization of the actin cytoskeleton and neuronal growth cone collapse.  In contrast to mature NGF, the precursor form (proNGF) promotes neuronal apoptosis (in vitro) (By similarity).  Inhibits metalloproteinase-dependent proteolysis of platelet glycoprotein VI (By similarity).  Binds lysophosphatidylinositol and lysophosphatidylserine between the two chains of the homodimer.  The lipid-bound form promotes histamine relase from mast cells, contrary to the lipid-free form (By similarity).
What are the official names of this protein?
Beta-nerve growth factor, Beta-NGF.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted. Endosome lumen. Note=ProNGF is endocytosed after binding to the cell surface receptor formed by SORT1 and NGFR.
Protein: TAGH_STAAR
Sequence: MNVSVNIKNVTKEYRIYRTNKERMKDALIPKHKNKTFFALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRNGEVSVIAISAGLSGQLTGIENIEFKMLCMGFKRKEIKAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDEALSVGDQTFAQKCLDNIYEFKEQNKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYGELDDVLPKYEAFLNDFKKKSKAEQKEFRNKLDESRFVIK
What is the function of this protein?
Part of the ABC transporter complex TagGH involved in teichoic acids export.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Teichoic acids export ATP-binding protein TagH.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Teichoic acids exporter (TC 3.A.1.104.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MUTS_LACJO
Sequence: MAKKDTTPMMKQYYEIKEQYPDAFLFYRVGDFYELFEDDAIKGAQILELTLTHRSNKTKNPIPMAGVPHLAVDTYVNTLVEKGYKVALCEQLEDPKKAKGMVKRGIIQLITPGTMMQERPDQAKDSNYLTSVISTNSGFGLAYSDLSTGETFSTHLADFEAVANELLSLQTREVVYNGHLTDLNKDFLKKANITVSEPVEVEGEHAEISYVAQNLTDDAEIKATKQLVAYLLSTQKRSLAHLQVAQSYEPTQYLQMSHTVQTNLELIKSAKTSKKMGSLFWLLDKTSTAMGGRLLKSWIERPLLSVTEITRRQEMVQALLDDYFTREKVIDSLKGVYDLERLTGRIAFGSVNAREMLQLAHSLGAIPEILNALLETNNPHLQNFAKQIDPLKGIHDLIVNTIVDNPPLPTTEGGLIREGVSEQLDRYRDAMNNGKKWLSEMESHEREVTGINNLKVGYNKVFGYYIEVTNSNKSKVPTDRYTRKQTLTNAERYITPDLKEHEALILEAEAKSTGLEYDLFVKLREDVKKYIPALQKLAKQIASLDVLTNFATVSEQNNYVRPNFVTDKQEINVVNGRHPVVEQVMTAGSYIPNDVKMDQDTNIFLITGPNMSGKSTYMRQMALIAIMAQIGSFVPADSATLPIFDQIFTRIGAADDLISGQSTFMVEMSEANDALQHATKRSLVLFDEIGRGTATYDGMALAGAIVKYLHDKVGAKALFATHYHELTDLDQTLKHLKNIHVGATEENGKLIFLHKILPGPADQSYGIHVAQLAGLPHKVLREATTMLKRLEKQGASELQPASEQLDLFVPEEASAPAISDDEKDVLDEIQNVYLADKTPLQVMELVAQWQQELKDKD
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: NICN1_MOUSE
Sequence: MSRVLVPCHVKSTVALQVGDMRTSQGRPGVLVVDVTFPNIAPFELQEIMFKNYYTAFLSIRVRQQSSMHTAAKWVTCLRDYCLMPDPHSEEGAQDYVSLFKHQMLCDMNRVLELRLILRQPSPLWLSFTVEELQIYQQGPKSPSLAFPKWLSHPVSNEQPAPRLEGLPDPSRVSSEVQQMWALTEMIRASHTSTRIGRFDVDGCYDLNLLSYT
What are the official names of this protein?
Nicolin-1, Tubulin polyglutamylase complex subunit 5, PGs5, p24.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSB2_THECD
Sequence: MTERERGQGLPAEFFAVGTASFVELLSRTAPQLLPVNRVRDGSHPMPDIPHGTTIVAVRYPEGVMLAGDRRATSGNLIAQKDLEKVHRADEHSAVAMAGTVGLALEMIRLLQVELEHYEKLQSAKLSLPGKARRLGAVIRANLAHAMQGLAVVPVFAGYDLDAGVGRIYNYDITGMPQESRDFHAEGSGSPFARGALKKLYRPDLTEAEAAAVCVQALYDAAEDDAATAGPDLARRIFPTIATVTADGYRRLPEQEVAELTESVVGARRQRPDGPVAPLR
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta 2, 20S proteasome beta subunit 2, Proteasome core protein PrcB 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_STAA1
Sequence: MERTFLMIKPDAVQRNLIGEVISRIERKGLKLVGGKLMQVPMELAETHYGEHQGKPFYNDLISFITSAPVFAMVVEGEDAVNVSRHIIGSTNPSEASPGSIRGDLGLTVGRNIIHGSDSLESAEREINLWFNENEITSYASPRDAWLYE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUP1A_XENLA
Sequence: MADIPDNAPQHCPGTDSTEAGKSSACQGCPNQSICASGAAAGPDPAIEEIKEKMSLVKHKILVLSGKGGVGKSTFSAHLAHGLAQDEGKEVALLDVDICGPSIPKMMGLEGEQVHQSGSGWSPVYVEDNLAVMSVGFLLSSPDDAVIWRGPKKNGMIKQFLRDVDWGDVDYLIVDTPPGTSDEHLSVVQYLSAAGIDGAVIITTPQEVSLQDVRKEINFCRKVKLPIIGVVENMSGFICPKCKNESQIFPPTTGGAEKMCTDLSVSLLGKVPLDPNIGKSCDTGKSFFTEIPDSPATLSYRKIIQRIQDYCEKKK
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery.  Required for maturation of extramitochondrial Fe-S proteins.  The nubp1-nubp2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor nubp1-A, Nucleotide-binding protein 1-A, NBP 1-A.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRF_STRM5
Sequence: MSRAPLPLRDDERLIFALDVPDRVQALDWVERLGDSVAFYKIGMELLASGEYFQVLDELARRDKRVFVDLKFFDIPATAAAVIKRLSQWPVSYATIHGWHPAMMEACAAANSSDMRLLAVTVLTSMGRPDLAQMGIDREPVDVVVERALAAQAAGIDGVIASGQEAGPIRAATGAGFSIVCPGIRPGGPVGDDQKRTVGVAQAFADGADAIVIGRPIRLAADPQAAARAIQQEIASALAAR
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: UKL4_ARATH
Sequence: MGSKSVVDMIEAASRAHFSGLHVNGHMNGLEPSALKETTSASEDIQRQPFVIGVAGGAASGKTTVCDMIIQQLHDQRVVLINLDSFYHNLTEEELARVHEYNFDHPDAFDTEHLLSCMEKLRQGQAVDIPKYDFKTYRSSVFRRVNPTDVIILEGILLFHDPRVRKLMNMKIFVCTDADVRLARRIKRDTVENGRDIGTVLDQYSKFVKPAFDDFILPTKKYADIIIPRGGDNHVAIDLIVQHICTKLGQHDLCKIYPNLYVIHSTFQIRGMHTLIRDSQTTKHDFVFYSDRLIRLVVEHGLGHLPFTEKQVITPTGCVYSGVDFCKRLCGVSVIRSGESMENALRACCKGIKIGKILIHREGDNGQQLVYEKLPNDISERHVLLLDPILGTGNSAVEAINLLISKGVPEGNIIFLNLISAPQGVHVVCKKFPRIKIVTSEIDNGLNEEFRVIPGMGEFGDRYFGTDDD
What is the function of this protein?
Involved in the pyrimidine salvage pathway.  The uracil phosphoribosyltransferase (UPRT) activity, that catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate, is unsure.
What are the official names of this protein?
Uridine kinase-like protein 4.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the UPRTase family.
Protein: AWAT1_HUMAN
Sequence: MAHSKQPSHFQSLMLLQWPLSYLAIFWILQPLFVYLLFTSLWPLPVLYFAWLFLDWKTPERGGRRSAWVRNWCVWTHIRDYFPITILKTKDLSPEHNYLMGVHPHGLLTFGAFCNFCTEATGFSKTFPGITPHLATLSWFFKIPFVREYLMAKGVCSVSQPAINYLLSHGTGNLVGIVVGGVGEALQSVPNTTTLILQKRKGFVRTALQHGAHLVPTFTFGETEVYDQVLFHKDSRMYKFQSCFRRIFGFYCCVFYGQSFCQGSTGLLPYSRPIVTVVGEPLPLPQIEKPSQEMVDKYHALYMDALHKLFDQHKTHYGCSETQKLFFL
What is the function of this protein?
Acyltransferase that catalyzes the formation of ester bonds between fatty alcohols and fatty acyl-CoAs to form wax monoesters (PubMed:15671038).  Shows a strong preference for decyl alcohol (C10), with less activity towards C16 and C18 alcohols (PubMed:15671038).  Shows a strong preference for saturated acyl-CoAs (PubMed:15671038).
What are the official names of this protein?
Acyl-CoA wax alcohol acyltransferase 1, Diacylglycerol O-acyltransferase 2-like protein 3, Diacylglycerol acyltransferase 2, Long-chain-alcohol O-fatty-acyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol acyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SYGB_VIBCH
Sequence: MAKEFLIELGTEELPPKQLRTLAEAFAANFAAELATADIAHEGVTWFATPRRLALKVANLAESQPDRVVEKRGPAVNVAFDADGKPTKAAEGWARGNGITVEQAERLVTDKGEWLLFKEQVQGQQTASVVVEMAAKALANLPIAKPMRWGDKETQFIRPVKTLTILFGSELIQGEILGVASARTLRGHRFMGEAEFTIESAEQYPAILEERGKVIADYATRKAMIIEGSQQAAQQLGGIADLEDALVEEVTSLVEWPVVMTAKFEEKFLKVPAEALVYTMKGDQKYFPVYDASKKLLPNFIFVSNIESKEPRHIVEGNEKVVRPRLADAEFFFNTDRKRPLVDRLPLLENAIFQQQLGTIKDKTDRITELAGYIAEQIGADVEKSKRAGLLAKCDLMTSMVFEFTDTQGVMGMHYARHDGEAEEVAVALNEQYMPRFAGDELPSRGVSAAVAMADKLDTIVGIFGIGQAPKGSDPFALRRASLGVLRILVEYGYQLDLVDLIAKAKSLFGDRLTNANVEQEVIEFMLGRFPTWYQDAGFSIDIIQAVLARNPTKPADFDQRVKAVSHFRALEEAEALAAANKRVGNILAKYDGELGEEIDLALLQEDAEKALAEAVEIMAEALEPAFATGNYQEALSKLAGLRAPVDAFFDNVMVMADDEALKKNRLTLLNKLRNLFLQIADISLLQK
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOD_MYCBO
Sequence: MTAIADSAGGAGETVLVAGGQDWQQVVDAARSADPGERIVVNMGPQHPSTHGVLRLILEIEGETVVEARCGIGYLHTGIEKNLEYRYWTQGVTFVTRMDYLSPFFNETAYCLGVEKLLGITDEIPERVNVIRVLMMELNRISSHLVALATGGMELGAMTPMFVGFRAREIVLTLFEKITGLRMNSAYIRPGGVAQDLPPNAATEIAEALKQLRQPLREMGELLNENAIWKARTQGVGYLDLTGCMALGITGPILRSTGLPHDLRKSEPYCGYQHYEFDVITDDSCDAYGRYMIRVKEMWESMKIVEQCLDKLRPGPTMISDRKLAWPADLQVGPDGLGNSPKHIAKIMGSSMEALIHHFKLVTEGIRVPAGQVYVAVESPRGELGVHMVSDGGTRPYRVHYRDPSFTNLQSVAAMCEGGMVADLIAAVASIDPVMGGVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RGI1_YEAS7
Sequence: MTKKDKKEVKVQTVTTEDGETVKVFEDLQGFETFIANETEDDDFDHLHCKLNYYPPFVLHESHEDPEKISDAANSHSKKFVRHLHQHIEKHLLKDIKQAVRKPELKFHEKSKEETFDKITWHYGEETEYHGRPFKIDVQVVCTHEDAMVFVDYKTHPVGAN
What is the function of this protein?
Involved in the control of energetic metabolism and significantly contribute to cell fitness, especially under respiratory growth conditions.
What are the official names of this protein?
Respiratory growth induced protein 1.
What is the protein family that this protein belongs to?
Belongs to the RGI1 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ALDEC_SYNE7
Sequence: MPQLEASLELDFQSESYKDAYSRINAIVIEGEQEAFDNYNRLAEMLPDQRDELHKLAKMEQRHMKGFMACGKNLSVTPDMGFAQKFFERLHENFKAAAAEGKVVTCLLIQSLIIECFAIAAYNIYIPVADAFARKITEGVVRDEYLHRNFGEEWLKANFDASKAELEEANRQNLPLVWLMLNEVADDARELGMERESLVEDFMIAYGEALENIGFTTREIMRMSAYGLAAV
What is the function of this protein?
Catalyzes the decarbonylation of fatty aldehydes to alkanes.  Requires the presence of ferredoxin, ferredoxin reductase and NADPH for in vitro decarbonylase activity (By similarity).  Involved in the biosynthesis of alkanes, mainly heptadecane and pentadecane.
What are the official names of this protein?
Aldehyde decarbonylase, AD, Fatty aldehyde decarbonylase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde decarbonylase family.
Protein: B2MG_SAPAP
Sequence: MARFVVAALLVLLCLSGLEAIQHAPKIQVYSRHPAENGKPNFLNCYVSGFHPSDIEVDLLKNGKKIEKVEHSDLSFSKDWSFYLLYYTEFTPNEKDEYACRVSHVTFPTPKTVKWDRNM
What is the function of this protein?
Component of the class I major histocompatibility complex (MHC).  Involved in the presentation of peptide antigens to the immune system (By similarity).
What are the official names of this protein?
Beta-2-microglobulin.
What is the protein family that this protein belongs to?
Belongs to the beta-2-microglobulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MECA_STAAR
Sequence: MRIERVDDTTVKLFITYSDIEARGFSREDLWTNRKRGEEFFWSMMDEINEEEDFVVEGPLWIQVHAFEKGVEVTISKSKNEDMMNMSDDDATDQFDEQVQELLAQTLEGEDQLEELFEQRTKEKEAQGSKRQKSSARKNTRTIIVKFNDLEDVINYAYHSNPITTEFEDLLYMVDGTYYYAVHFDSHVDQEVINDSYSQLLEFAYPTDRTEVYLNDYAKIIMSHNVTAQVRRYFPETTE
What is the function of this protein?
Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
What are the official names of this protein?
Adapter protein MecA.
What is the protein family that this protein belongs to?
Belongs to the MecA family.