PharMolix/UniProtQA huggingface dataset:
Protein: GSH1_VIBC1
Sequence: MTDFAARLKQVASNPEVFKQFGRGVERETLRYRQDGHLATTPHPEGLGSAFTNKWITTDFSESLLEFITPVSHEIPELMGQLKDIHHFTQTKMGEEKMWPLSMPCYVGSEDDIQLAQYGSSNSAKMKTLYREGLKRRYGSLMQIISGVHFNFSFPESFWDALHGEQDEEARQDTKSDAYFALIRNYYRFGWMIPYFFGASPALCGSFIQGRETDLPFEKIGGTLFLPKATSLRLSDLGYTNSAQSVLKIGFNSIDQYLDGLSDAIRRPSEEFAEIGVKVDGEYRQLNSNILQIENELYAPIRPKRVTKSGEKPSEALQRGGVEYIEVRSLDVNPFSAVGVSEEQVRFLDLFLTWAALSDSDPMDNCELECWRDNWNKVIVSGREKGLMLQIGCQGERLSLQDWAHRVFADLRQIAVEMDSAAGGNAYQAVCDKLESWIDEPELTISGQLLELTKEHGGLGKVGCALGMKFREENLAHSYEQYSADAMETEVATSLEKQKQAEQSDTLSFDDFLEDYFAYLKQ
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
Protein: RSMA_METM5
Sequence: MRQSKKLGQCFLKDKNFVKKAINRAEITNKDVVLELGLGEGALTKELAKIAKKVYVIELDERLKPFADEITSEFENVEIIWSDALKVDLKNLGFNKIVANLPYQISSPITFKFLDVDFETAVLMYQYEFAKRMAGKPDTKEYSRLSVAVQYNADVEFICKVPPSAFSPKPDVNSAIVKLTKREPKYFVKDEKFFKKVLKAMFQHRNRTIKRALIDSSHEIEIDRDNLKEILEKVESEFDFSERVFKTSPEKIGYLSNLLYDEI
What is the function of this protein?
Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Probable ribosomal RNA small subunit methyltransferase A, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GAL1_YERPE
Sequence: MSLKQHTQTIFRQQFDRESDITIKAPGRVNLIGEHTDYNDGFVLPCAINYETVISCGKRDDRQIRVIAADYENQQDIFSLDAPIVPHPEYRWADYVRGVVKHLQMRNADFGGADLVICGNVPQGAGLSSSASLEVAVGQALQSLYQLPLSGVELALNGQEAENQFVGCNCGIMDQLISALGKKDHALLIDCRTLETRAVPMPENMAVVIINSNIQRGLVDSEYNTRRQQCEAAARFFGVKALRDVEPSLFFSIQDELDPVVAKRARHVISENARTLAAADALAAGNLKLMGQLMQESHISMRDDFEITVPPIDRLVEIVKSVIGDQGGVRMTGGGFGGCIIALMPLELVEQVRTTVAQEYPAHSGGKKETFYVCQASQGAGLC
What is the function of this protein?
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ITM2B_PIG
Sequence: MVKVTFNSALAQKEAKKXEPKSGEEALIIPPDTXAVDCKDPDEVVPVGQRRAWCWCMCFGLAFMLAGVILGGAYLYKYFALQPDDVYYCGIKYIKDDVILNEPPANAPAARYQTIEENIKIFEEDGVEFISVPVPEFADSDPANIVHDFNKKLTAYLDLNLDKCYVIPLNTSIVMPPRNLLELLINIKAGTYLPQSYLIHEHMVITDRIENIDHLGFYIYRLCHDKETYKLQRKETVKGIQKREASNCATIRHFENKFAVETLICS
What is the function of this protein?
Bri23 peptide prevents aggregation of APP amyloid-beta protein 42 into toxic oligomers.
What are the official names of this protein?
Integral membrane protein 2B, Immature BRI2, imBRI2, Transmembrane protein BRI, Bri.
What is the protein family that this protein belongs to?
Belongs to the ITM2 family.
What are the subcellular locations of this protein?
[Integral membrane protein 2B]: Golgi apparatus membrane; Single-pass type II membrane protein. Note=Immature BRI2 (imBRI2) is cleaved by furin in the Golgi into mBRI2 and a Bri23 peptide. mBRI2 is transported to the plasma membrane and Bri23 peptide is secreted. SUBCELLULAR LOCATION: [BRI2, membrane form]: Cell membrane; Single-pass type II membrane protein. Endosome membrane; Single-pass type II membrane protein. Note=Mature BRI2 (mBRI2) needs to be transported from the endoplasmic reticulum compartment to the cell membrane in order to be able to inhibit APP processing. SUBCELLULAR LOCATION: [Bri23 peptide]: Secreted. Note=Detected in the cerebral spinal fluid (CSF). SUBCELLULAR LOCATION: [BRI2C, soluble form]: Secreted.
Protein: LEUD_SHEDO
Sequence: MQAFTAHSGLAVAIDSANIDTDQIIPKQFLSKVTRDGFGVHLFHDWRYLDDAGEKPNPEFVLNQSRYKGASILLAQENFGCGSSREHAPWALADFGLRVVIAPSFADIFYGNAINNGLLPVVLTQAQVQQLMDEVQGELGAQVSVDLQLLRVISPSGAEFPFSLVESARHKLLNGLDAVGETLTHGQAISAYEANIPAWLA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: TFKL3_HUMAN
Sequence: METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETLPLQPKHLREAVRRLKPKGLFPNSNCKRIMF
What are the official names of this protein?
TATA-box-binding protein-associated factor 11-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the TAF11 family.
Protein: RS3_ACIAD
Sequence: MGQKVHPIGIRLGVVKRHNANWYANPKQYAEYLLKDLQVREFLTKKLKSAMVSNILIERPTGAAKVTISTARPGIVIGKKGEDIEKLQRELTNIMGVPAQVSINEIDRPDLDARLVAEAIASQLEKRVMFRRAMKRAVQNSMRAGAKGIKVEVSGRLGGAEIARTEWYREGRVPLHTLRADIDYATMRAETTYGTIGVKVWIFRGEILGGMKQVMNPAPQEERPAKRGRGRGEGQERRGRRSDRAADKGE
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: SBCC_STAA8
Sequence: MKPLHLKLNNFGPFLKEEIDFSKIDNNELFLISGKTGSGKTMIFDAMTYALFGKASTEQREENDLRSHFADGKQPMSVTFEFQLNHRIYKVHRQGPYIKEGNTTKTNAKFDVFEMVDGKYEIRESKVISGTQFIIELLGVNADQFRQLFILPQGEFKRFLISNSREKQGILRTLFDSEKFEAIREILKEEVKKEKAQIENRYQQIDLLWQEIESFDDDNIKGLLEVATQQIDKLIENIPLLQARSKEILASVNESKETAIKEFEIIEKKTLENNILKDNINQLNKNKIDFVQLNEQQPEIEGIEAKLKLLQDITNLLNYIENREKIETKIANSKKDISKTNNKILNLDCDKRNIDKEKKMLEENGDLIESKISFIDKTRVLFNDINKYQQSYLNIERLRTEGEQLGDELNDLIKGLETVEDSIGNNQSDYEKIIELNNTITNINNEINIIKENEKAKAELDKLLGSKQELENQINEETSILKNLEIKLDRYDKTKLDLNDKESFISEIKSAVNIGDQCPICGNEIQDLGHHIDFDSIAKRQNEIKEIEANIHAIKSNIAVHNSEIKFVNEKISNINIKTQSDFSLEVLNKRLLENENALNNQRDLNKFIEQMKEEKDNLTLQIHNKQLRLNKNESELKLCRDLITEFETLSKYNNITNFEVDYKKYVQDVNQHQELSKEIEDKLMQLSQRKLIEQNNLNHYENQLETYNNDLELNEQSIEMEMSRLNLTDDNDIDEIIAWRGEQEELEQKRDTYKKRYHEFEMEIARLESLTKDKELLDSDKLKDEYELKKGKMNTLIDEYSAVHYQCQNNINKTQSIVSHINYLNQELKDQQEIFQLAEIVSGKNNKNLTLENFVLIYYLDQIIAQANLRLATMSDNRYQLIRREAVSHGLSGLEIDVFDLHSNKSRHISSLSGGETFQSSLALALGLSEIVQQQSGGISLTSIFIDEGFGTLDQETLETALDTLLNLKSTGRMVGIISHVSELKNRIPLVLEVKSDQYQSSTRFKRN
What is the function of this protein?
SbcCD cleaves DNA hairpin structures.  These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions.  The complex acts as a 3'->5' double strand exonuclease that can open hairpins.  It also has a 5' single-strand endonuclease activity (By similarity).  Is probably part of the SOS regulon and involved in DNA recombination and repair.
What are the official names of this protein?
Nuclease SbcCD subunit C.
What is the protein family that this protein belongs to?
Belongs to the SMC family. SbcC subfamily.
Protein: QUEF_STAA2
Sequence: MAHGRQQDELQDITLLGNQDNTYNFDYRPDVLESFDNKHQGRDYFVKFNCPEFTSLCPITGQPDFATIYISYIPNVKMVESKSLKLYLFSFRNHGDFHEDCMNIIMNDLIELMDPHYIEVWGKFTPRGGISIDPYTNYGRPNSKYEKMAEHRLMNHDLYPEKIDNR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQOR_SHIFL
Sequence: MAKVLVLYYSMYGHIETMARAVAEGASKVDGAEVVVKRVPETMPPQLFEKAGGKTQTAPVATPQELADYDAIIFGTPTRFGNMSGQMRTFLDQTGGLWASGALYGKLASVFSSTGTGGGQEQTITSTWTTLAHHGMVIVPIGYAAQELFDVSQVRGGTPYGATTIAGGDGSRQPSQEELSIARYQGEYVAGLAVKLNG
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: GPMA_ESCF3
Sequence: MAVTKLVLVRHGESQWNKENRFTGWYDVDLSEKGVSEAKAAGKLLKEEGYSFDFAYTSVLKRAIHTLWNVLDELDQAWLPVEKSWKLNERHYGALQGLNKAETAEKYGDEQVKQWRRGFAVTPPELTKDDERYPGHDPRYAKLSEKELPLTESLALTIDRVIPYWNETILPRMKSGERVIIAAHGNSLRALVKYLDNMSEEEILELNIPTGVPLVYEFDENFKPLKRYYLGNADEIAAKAAAVANQGKAK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: TRPF_CAMJR
Sequence: MLKLKICGIKDEKNAKDLAFLNIDFFGLIFAKSPRRVSLEQARNLSAIFHEKDKKVVGVFVDENLEQILRCIKEAKLDGIQIYRTITKEEFEILKVQNVFVWQVISVENSLDLKSEIFANLVLFDAKGILKGGNGISFDWTLLGSYTKDFILAGGIGLDNVHKAVKTGAKILDLNSKLEDEKGLKDINKIKQILKELKK
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: TRPE_HAEIN
Sequence: MNIQTQAFIAVTAQPIPYYADTTAIFNTLCQSNSNSLLLDSAEIGSKNSLQSLILVNAAVKITCLGHNVTFKALNNNGKQVLKEIHPKLTALGKVSAVNFEDEFSVQFLPLDNQLDEDSKLQSATIFDGLRVISSLYQHSQTPIFLGGLFAYDLVANFIPMDGITLKNDGINCPDYSFYLAEHLITIDHQNQQATLKSFCFAQEEQVNIAKTSLSIAQKLKNIDHVLSIKAASDEVKTNFDDPEFTGIVKALKHHINIGDVFQIVPSRRFSLACPNTLASYAQLKQNNPSPYMFYMNDEDFILFGASPESALKYAPENRQLEIYPIAGSRPRGFDAHGNIDPELDARLELELRLDHKEQAEHLMLVDLARNDIARVCQSGTRKVAELMQVDRYSHIMHLVSRVVGKLRPELDALHAYQACMNMGTLTGAPKIKAMQLIYQFEQQKRHSYGGAVGYLTSDGHFDTCIVIRSAFVQNGMAHVQAGCGEVLDSDPQMEADETRHKAAAVLKAIRQVNTQAK
What is the function of this protein?
Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan.  In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate.  In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia (By similarity).
What are the official names of this protein?
Anthranilate synthase component 1, AS, ASI.
What is the protein family that this protein belongs to?
Belongs to the anthranilate synthase component I family.
Protein: TRMB_PSE14
Sequence: MTDSHVPHPESPAVEEGEERPHRRIKSFVMRAGRMTEGQQRGLDQGLPLYGLSLTDAPVDFDQVFGRAAPRTLEIGFGMGHSLLEMAAAAPEHDFIGVEVHSPGVGALLNGVLTQGLTNVRVYDCDAIEVLNRCVADNSLDRLMLFFPDPWHKSRHHKRRIVQPEFAALVRSKLKVGGVFHMATDWGPYAEYMLEVMSVASGYRNQAEDNQYVPRPAERPITKFERRGEKLGHGVWDLKFEKVD
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: KDSB_SHEB5
Sequence: MNVTLLIPARYGSSRFPGKPLAPINGKPMIQHVYERASLAKGLTNIYVATDDDRIKAAVEGFGGKVVMTSPEAASGTDRINDAINQLGLKDDDLVINLQGDQPLIDPTSIEQVISLFERHPGEFEMATLGFEIVNKAELDDPMHVKMVFDNNNYALYFSRSRIPFGRDTQDYPVYKHLGVYAYTRKFVQAFAALPLGRLEDLEKLEQLRALEYGHKIKIAISAFDSIEVDTPEDIRKCEQRLAVD
What is the function of this protein?
Activates KDO8N (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in the Shewanella genus.
What are the official names of this protein?
8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase, CMP-8-amino-3,8-dideoxy-manno-octulosonate synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BGAL_PECAS
Sequence: MSDSVLSNPTRQHATLREILARRDWENPACTNYQRLPAHPPFNSWRNVAAAHQDEPSQRLRRLNGEWKFSYFTRPEAVPESWLQQDLPDSATIPVPSNWQLQGYDTPIYTNVKYPIPVNPPYVPEDNPTGCYSLTFKVNHDWLSCGQTRVIFDGVNSAFYLWCNGHWVGYSQDSRLPAEFDISRYLTTGENRLAVMVLRWSDGSYLEDQDMWRMSGIFRDVTLLHKPTVHLGDIQLTTPLSADFRHGTLDIQVKATLSESEAKNYRVHAQLWRGNNLIGETRQAFGSDIVDERGTYHDRASLRLDVTRPDLWSAELPHLYRAVIALETAEGELLEAEAYDVGFRKVEISNGLLLLNGKPLLIRGVNRHEHHPQNGQVMDEETMRRDIMLMKQHNFNAVRCSHYPNHPLWYRLCDRYGLYVVDEANIETHGMQPMNRLSDDPMWLPAYSERVSRMVQRDRNHPCIIIWSLGNESGYGANHDALYQWIKRHDPTRPVHYEGGGANSRATDIVCPMYARVDEDQPFPNVPKWSISKWISMPNEHRPLILCEYAHAMGNSLGGFARYWKAFRQYPRLQGGFIWDWVDQALIRHDEQGNAYWAYGGDFGDMPNDRQFCLDGLLFPDRTPHPSLYEAQRAQQHIQFVWQAESPCELRVTSEYLFRHTDNEQLNWHITLDDKTLVEGSLPLKLAPQATQTLTLLESLPTVDRAGEIWLNVEVVQPKETAWSKANHRCAWDQWQLPIPLHLPEASCSKQKIPPVLRASDIYFDVVQGEQHWRFNRQSGLLEQWWTADTPALLTPLQDQFVRAPLDNDIGISEVDRIDPHAWAERWKSAGLYQLQTQCVAIQADQLADAVHIVTEHVFRHAGQILLRSKKRWQIDAYGVMTVDVDVDVATVLPSLARVGLSCQLADVAPQVSWIGLGPHENYPDRQLAAQHGHWNLPLDDLHTPYIFPSENGLRCNTRALTYGKWAITGNFHFGLSRYGLTQLMTCTHHHLLEKEKGVWLNLDGFHMGIGGDDSWSPSVHCDDLLTATHYHYRVAIQRH
What are the official names of this protein?
Beta-galactosidase, Beta-gal, Lactase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 2 family.
Protein: BLAT_SALTI
Sequence: MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
What is the function of this protein?
TEM-type are the most prevalent beta-lactamases in enterobacteria; they hydrolyze the beta-lactam bond in susceptible beta-lactam antibiotics, thus conferring resistance to penicillins and cephalosporins.
What are the official names of this protein?
Beta-lactamase TEM, Penicillinase.
What is the protein family that this protein belongs to?
Belongs to the class-A beta-lactamase family.
Protein: BIGA_SALTY
Sequence: MNPMQKKKLISIAIALTLQSYYIPAIAAENNDDEKECPSNISSLPKEKRAKLSPTCLATPENDNHWGWVAGGVAALVAGVAIGVENNGGGDSNHSYTPPKPDNGGDVTPPDDGGNVTPPDDGGNVTPPDDGGDDNVTPPDDSGDDDVAPPDDSGDDDVTPPDDSGDDDVTPPDDSGDGDVTPPDDSGDDDVTPPDDSGDDDVTPPDDSGDDDVTPPDDSGDDDVTPPDDSGDDDVTPPDDSGDDDDTPPDDSVITFSNGVTIDKGKDTLTFDSFKLDNGSVLEGAVWNYSEQDNQWQLTTADGKTLNVTGWDVTDANAAVIEGTQENGLYWKYDSRGYLIIADDNTTVISGDDQAHNSDRGMDISGQDRTGVIISGDRTVNTLTGDSSVTDGATGMVISGDGTTNTISGHSTVDNATGALISGNGTTTNFAGDIAVSGGGTAIIIDGDNATIKNTGTSDISGAGSTGTVIDGNNARVNNDGDMTITDGGTGGHITGDNVVIDNAGSTTVSGADATALYIEGDNALVINEGNQTISGGAVGTRIDGDDAHTTNTGDIAVDGAGSAAVIINGDNGSLTQAGDLLVTDGAMGIITYGTGNEAKNTGNATVRDADSVGFVVAGEKNTFKNKGDIDVSLNGTGALVSGDMSQVTLDGDINVVSVQDSEGVFSSATGVSVSGDSNAVDITGNVNISADYGQDDLAAGAPPLTGVVVGGNGNTVTLNGALNIDDNDLSATGGQYLDVVGLSVTGDDNDVEIDGGINITHSEDPLDGTSADITGISVSGNSTVTLNGHSTIDTNTVVGGHVVLARVNNGGSLILGDDSVVDVNVSYIPTGYYTYNALLMADGEGTSIENKGDITSHGVYSVIRADNGSEVSNSGDILVYATSSNSSEDRAAITRASGEGSAVHNKAGGDITLISDQTPQGSGGIEVYPLKWYTHTFYAMMASDYGDVVNDEGATIHLQGAGVYGVTASRGKALNEGNIYLDGLVPTLDDENNITSTSYWQPSSLYLTSSGMVAGSTDADGDATAINTGNITVNNAGFGMMALNGGTAINQGVITLTADDGVTGQADELVGMAALNGGVVINDTSGVINIDADYGQAFLSDSSSYIINNGSINLNGSPMDDTDSHMGGTPTDKIWIQSLPGSGDSDTRTSDTGFFTAGTLANYGTETLNGDVDVNGGWLYNEAGASLTVNGTVTINGGANALANYGTLDADAISTWHSLFNEADGSITTDLLTLNGDVTFYNNGDFTGSIAGTSYQQEIVNTGDMTVAEDGKSLVSGSFYFYNEEDATLTNSGSAVEGGENTIINLTRANDSLTQVNSGTITATNGYSAITTVNGSNDPKWIWNTATGVINGINPDAPLINLGRGYNFGNQGTINVQGDNAVAISGGTSSYVINLVNSGTINVGTEQGKEDGTNGTGLIGIKGNGNATTINNTADGVINVYADDSYAFGGKTKAIINNGEINLLCDSGCDIYAPGTTGTQNDHNGTADIVIPDATTAPTEGSIPTPPADPNAPQQLSNYIVGTNADGSSGTLKANNLVIGDNVKVDTGFTSGTADTTVVVDNAFTGSNIQGADNITSTSVVWNAQGSQDADGNVDVTMTKNAYADVATDSSVSDVAQALDAGYTNNELYTSLNVGTTAELNSALKQVSGAQATTVFREARVLSNRFTMLADAAPQIKDGLAFNVVAKGDPRAELGNDTQYDMLALRQTLDLTASQNLTLEYGIARLDGDGSKTAGDNGLTGGYSQFFGLKHSMAFDEGLAWNNSLRYDVHNLDSSRSVAYGDVNKIADSDMRQQYLEFRSEGAKTFTMMGDALKVTPYAGVKFRHTMEDGYKERSAGDFNLSMNSGNETAVDSIVGLKLDYAGKDGWSATATLEGGPNLSYSKSQRTASLQGAAGQSFGVDDGQKGGGVNGLATIGVKYSSNDTALHLDAYQWKEDGISDKGFMLNVKKTFR
What are the official names of this protein?
Putative surface-exposed virulence protein BigA.
Protein: CSRA_SHEON
Sequence: MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHREEIYQRIQSEKSGTPSEGGNF
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAND_METSB
Sequence: MRKLVGGKLHGIRVTESNLEYHGSITLDPAHCEAAGILPLEFVEIWNKNSGARITTYVILGQRGSRCCVLNGAAARTCQPGDELIICSSVYLDGAEITNLSPAVLTFDANNNIVERLHYSVTRDGAGHYQFGIVAEDGEILQPPLKSGMRQKRAS
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_BRUC2
Sequence: MANVVVVGSQWGDEGKGKIVDWLSERADVIVRYQGGHNAGHTLVIDGVSYKLSLLPSGLVRGKLSVIGNGVVVDPHHFVAEVEKLRGQGIDVTPDVLRVAENAPLILSIHRELDAMREGSNSGLKIGTTKRGIGPAYEDKVGRRAIRVIDLTEPETLRPKVERLLAHHNSLRRGMGLEEIAVETILTELTSVADQILPYIDQVWRVLDERRKAGARILFEGAQGALLDNDHGTYPFVTSSNTVAGQAAAGSGLGPTAIGYVLGITKAYTTRVGEGPFPTELNDEIGEFLGTKGHEFGVVTGRKRRCGWFDAVIVRQTVRTSGINGIALTKLDVLDGLEEIKICVAYELDGKRIDYLPSSMGAQARVKPIYETLPGWSETTAGARSWNDLPAQAVKYVRHIEELIGAPVAMLSTSPEREDTILVTDPFHD
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_CHLPN
Sequence: MPRIIGIDIPAKKKLKISLTYIYGIGSARSDEIIKKLKLDPEARASELTEEEVGRLNSLLQSEYTVEGDLRRRVQSDIKRLIAIHSYRGQRHRLSLPVRGQRTKTNSRTRKGKRKTVAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: NTPPB_PHOPR
Sequence: MTQPLLLASTSPFRKVLLDKFQYPFETANPNTDESSFSGESAEALVQRLAEQKAKACGNNYPEHLIIGSDQVCVINGKIIGKPHTVENACLQLKAASGQIVTFYTGLCLYNAKTGQSDVICEPFHVHFRQLTEQEIERYIEREMPLYCAGSFMCEGLGIALFNKLEGRDPNTLIGLPLIALREMLEKQGISIL
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP).  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
7-methyl-GTP pyrophosphatase, m(7)GTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YceF subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_NOCFA
Sequence: MSEKTVERGRRKVRIGYVVSDKMNKTIVVELEDRVKHPLYGKIIRTTSKVKAHDENEIAGVGDRVQLMETRPLSATKRWRLVEVLEKAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: LDH_GLOVI
Sequence: MQDRLFVSMEHPRALPETDLIKGAIVGAGAVGMAIAYSMLIQNTFDELVLVDIDRRKVEGEVMDLVHGIPFVEPSVVRAGTLADCRGVDVVVITAGARQREGETRLSLVQRNVEIFRGLIGEIMEHCPNAILLVVSNPVDVMTYVAMKLAGLPPSRVIGSGTVLDTARFRYLLAERLRVDPRSLHAYIIGEHGDSEVPVWSRANVAGAFLSEIEPAVGTPDDPAKMFEVFEHVKNAAYEIIERKGATSWAIGLATTQIVRAITRNQNRVLPVSVLMSGLHGIEEVCLAYPAVLNRQGIDRLVKFSLSPGEEEQLQRSARVMRQTLDGIQF
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDC_ZYMMO
Sequence: MDDKHQQRNLVIVTILSALILFGWSFVTKHWLSTPPAPTQQGKNQPKAELTAEESGDKPLKPVDQVLQETPRLPILTESVEGSVNLKGLRLDDLTLIRHRETLAKNSPAVRLFSPAGTENAWFTSFGWTGENVALPNADSLWKADSDKLTADHPVNFYWNNQQGQIFRITLSVDHDYMFNATESVINRGNSPVIVQPYVLTNHQGVFKTASSWTLHTGPIGVFNGSVNYHVDFADIDKATNNSIRNNTQGGWIGFSDKYWLTALAPHNQKIAIDTDFRSSSNHHYQADFTVAPVVVAAGKTASTSVDVFAGAKEVRVLDRYRDQLHLPHFDKAIDWGWFAIIEKVFFYYLDWLFLHVGNYGLAIILMVFTIRALIFPIANKQYASMASMRRLQPKMQAVRERYKNDEARMRQELVTLYQKEKVNPFAGCLPMFIQFPIFIALYKTLLVTIESRHQPFILWIKDLSAPDPLTPFNLFGLLHFTPPHFLMIGVLPIILGITMWLQFRASPQQLEPAQQQIMSFLPLISVIFMAPLAAGLQVYYIFNNLISLAQMMWLQHRHSTPEERQDRAERKRPSKKKA
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SUV42_CAEBR
Sequence: MSHAPGEGRPVSSLFPARCNEEVASQNATTMATLNEIELSEIEELSLNFKETPRQDHSMTPVELCYFDDFATTLVVDAVLNFSTHKMCKKRRYLYGDEQRVARELMERFRKDQDWTPAIYGFLNMRSVRSFIEKLAFNKQLEFRDHIIRFLNVFHHDSGYTIQECTRYSLEGNQGAKLVATRAWYRGDKIQRLSGVVCLLSTQDEDTILQPEGSDFSVMYSNRKRCSTLWLGPGAYINHDCRPTCEFVSHGSTAHIRVLRDMVAGDEITCFYGSEFFGPKNMDCECLTCEKTKRGKFSTSDEEENDEPSALSEKRIKYGLRSRSRV
What is the function of this protein?
Histone methyltransferase that specifically di- and trimethylates 'Lys-20' of histone H4 (H4K20me2/me3).  H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression.  Contributes to dosage compensation of X chromosome-relative to autosome-linked gene expression, possibly by converting H4K20me1 to H4K20m2/me3 on autosomes.  Involved in the regulation of growth and body fat metabolism downstream of the TOR complex 2 pathway.
What are the official names of this protein?
Histone-lysine N-methyltransferase Suv4-20, SET domain-containing protein 4.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar4-20 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome.