PharMolix/UniProtQA huggingface dataset:
Protein: RL27_TETTH
Sequence: MAKFLKYGRVVILLQGRFAGKKAVIVKSSEDGTKDRKFGHVLVAGVERSPKKVTKRMGSKKIQKRTSVKPFIKYVNLNHIMPTRYSVKELCDFKELVKEDKIKNNAKSEVRDTLKKVFVEKYRTINPEEKSASHTKFFFSKLRF
What are the official names of this protein?
60S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL27 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2855_ALKOO
Sequence: MAKKGGFPGMGGVNMNNMMKQVQKMQKQMEETQAQLEQKVLETSAGGGAVSIKITGKKEIVGISIKPEVVDPDDVEMLEDLIMAAMNEAIRAADDMMSSEMGKITGKMNMPGLF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Clos_2855.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: YCEH_ECOLI
Sequence: MKYQLTALEARVIGCLLEKQVTTPEQYPLSVNGVVTACNQKTNREPVMNLSESEVQEQLDNLVKRHYLRTVSGFGNRVTKYEQRFCNSEFGDLKLSAAEVALITTLLLRGAQTPGELRSRAARMYEFSDMAEVESTLEQLANREDGPFVVRLAREPGKRENRYMHLFSGEVEDQPAVTDMSNAVDGDLQARVEALEIEVAELKQRLDSLLAHLGD
What are the official names of this protein?
UPF0502 protein YceH, G20.3.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: SMKW_MOUSE
Sequence: MASNSKKKDVGSQYKVLFTLGHGSFGTVKLACHLKTKALVAIKMVELSKKNIRGIRAEIATLEKLQHPNIICLFQVLVTSKHINIVTEYIPGGNLFDIIKEDGPMHEEEARRIFGQVVSAVKYCHNQDIVHQDIKAQNILRDEEGNVKIIDFGLAIRCRSGTLLKRQCGTKSCFAPELVLQEPYDGKKADVWSLGVLLYFITTGYYPFRGSTMKEMEEKIATGTYDIPTHVSGQLENLIHQILTVPPEMRPSIEDIERHPWVKKTEVNNPTVTDPDYNIIEMLCGMGFDANEILESLQRKKYNESMGAYLILKAQVDKGLEHTSIISAKPVDQCPTPPPSPPAHPSISSLLLKRRASEPNFSLLHIQPSGEHRPVSLALPGHKVARSASMPPIALHYPEKKSNSSSFALHSGAVAAPSVGNSILEDELPVPPDQEYDMGACFGSTYTKQCDMETPSPPQKISRFKRMSKRIRACLAQLCCIPRAPKTKKKHTSSNKIAP
What is the function of this protein?
May play a role in sperm motility, especially in the regulation of flagellar function.
What are the official names of this protein?
Putative sperm motility kinase W.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. Smok subfamily.
Protein: CEMP1_HUMAN
Sequence: MGTSSTDSQQAGHRRCSTSNTSAENLTCLSLPGSPGKTAPLPGPAQAGAGQPLPKGCAAVKAEVGIPAPHTSQEVRIHIRRLLSWAAPGACGLRSTPCALPQALPQARPCPGRWFFPGCSLPTGGAQTILSLWTWRHFLNWALQQREENSGRARRVPPVPRTAPVSKGEGSHPPQNSNGEKVKTITPDVGLHQSLTSDPTVAVLRAKRAPEAHPPRSCSGSLTARVCHMGVCQGQGDTEDGRMTLMG
What is the function of this protein?
May play a role in development of the periodontium which surrounds and supports the teeth by promoting the differentiation of multi-potent cells from the periodontal ligament into cementoblasts to form the cementum (PubMed:21929512, PubMed:17509525, PubMed:21465469).  Binds hydroxyapatite and may promote the biomineralization of the cementum (PubMed:19393626).  Also promotes cell proliferation (PubMed:17509525, PubMed:21929512, PubMed:26011628).
What are the official names of this protein?
Cementoblastoma-derived protein 1, Cementum protein 1, Cementum protein 23, CP-23.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes to the nucleus of some cementoblasts.
Protein: HFQ_PHOLL
Sequence: MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVSHHSSNTSVGASVGNYHSGGVSAPAAQQESDGTE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: VM2T_PROFL
Sequence: GEECDCGSPSNPCCDAATCKLRPGAQCADGLCCDQCRFKKKRTICRIARGDFPDDRCTGQSADCPRWNGL
What is the function of this protein?
Inhibits fibrinogen interaction with platelets.  Acts by binding to alpha-IIb/beta-3 (ITGA2B/ITGB3) on the platelet surface and inhibits aggregation induced by ADP, thrombin, platelet-activating factor and collagen.
What are the official names of this protein?
Disintegrin triflavin, Platelet aggregation activation inhibitor, RGD-containing peptide, Trimestatin.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-II subfamily. P-IIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CARB_ARCFU
Sequence: MPKREDIRKIMVIGSGPIVIGQAAEFDYSGSQACKALREEGYEVVLVNSNPATIMTDPEMADRVYIEPLDAEIVAKIIERETPDALLPTLGGQTALNLAVQLTEMGVLDKYGVELIGAKFEAIKKAEDRELFKEAMRKIGLDVPKSDVAHDVSEALAIADEIGYPVVVRPAFTLGGTGGGIAYNREELREIAERGIKMSMINQVLIEEGVLGWKEFELEVMRDLADNVVIICSIENFDPMGVHTGDSITVAPAQTLTDVEYQYLRDAAIKIIREIGVETGGSNIQFAVHPENGRVVAIEMNPRVSRSSALASKATGFPIAKIAAKLAVGYTLDEIPNDITKETPASFEPTIDYVVVKIPRFAFDKFPTANQVLGSQMKSVGEVMAVGRTFEEALQKAIRSLEIGRYGLGCDGKDKEVTMEEIRERLRYPNASRVFYIRYALQKGMSVNEIYELTKIDPWFIDKIKNLVEFEEQLKQIAERMSIEEVPKEILKKAKELGYSDRQLAVIFNTTEREVRRVRKGKGLRVVYKMVDTCAAEFEAKTPYYYSTYEDENEALRSERKKVMILGAGPNRIGQGIEFDYCCVHAVFSLKDEGYETIMVNCNPETVSTDYDTSDRLYFEPITHEDVMNIYENEQPEGVIVQFGGQTPLNIARELEDSGARILGTSVDSIDIAEDRERFAELLERLNIPQPENGIAHSLEEAKEIARKIGFPVLVRPSYVLGGRAMEIVYDEETLERYITEALEVSPEKPILIDKFLEDAIEVEVDALCDGEEVVIGGIMEHIEEAGVHSGDSACVLPPVSLDEVTINTIVDYTRKLALALNVVGLINIQYAVKDGKVYVLEANPRASRTVPFVSKATGIPLAKIAAKLMMGKKLRELGVKEKLKLKHVAVKEAVFPFIKLPGVDPVLGPEMKSTGEVMGIDYDFGLAYYKAELAAGMKLPLKGTVFISVRRKDKNDRLLYLARKFKELGFRIIATDGTRDFLVQNGIEADLILKISQGRPNILDAIVNGQVDLIINTPSGKRGRTEGYMIRRAAVDYGVAHITTLAGAMAAVRAIEAVKSRKMVVKSIQEYHEES
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: CHLB_PROM5
Sequence: MELTLWTYEGPPHVGAMRVASSMKEIHYVLHAPQGDTYADLLFTMIERRGKRPPVTYTTFQARDLGGDTAELVKRNISEAVERFKPKTLLIGESCTAELIQDQPGALAKGMGFNIPIVNLELPAYSKKENWGASETFYQIIRTLLNDKTNEINNINPQRWKSLGRRPKVNILGPTLLGFRCRDDVIEIQRILSEQGIDTNVVAPLGSSPDDIKRLIDADINICLYQEIAETSCEWLKRKCGMEFTTTIPIGIKNTINFINEVHDKLGLPLTNKEELEHKSKLPWYSKSIDSNYLTGKRVFIFGDGTHAIAAAKIAKDELGFEVVGLGTYSREMARQVRAAAKDLNIEALITNSYLEVEDAMKKASPELVLGTQMERHSAKRLGIPCSVISTPMHVQDVPARYSPQMGWEGANVIFDDWVHPLMMGLEEHLIDMFKHDFEFVDGHQSHLGHTATKGLDNIEDEHGLKNDTLKKNGGVLWTESGRAELTKVPFFVRGKVKSNTEKYALSKGLPEISDETLYDAKAYFS
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (ChlN-ChlB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit B, DPOR subunit B, LI-POR subunit B.
What is the protein family that this protein belongs to?
Belongs to the ChlB/BchB/BchZ family.
Protein: SECG_DICDI
Sequence: MGSTSNSTKNTGSTTTTTTTAAPATTAKHSNSAPTRPSVHYYSSTGDIEKLSNLLNNSATSPDTPDSEKRTPLHHAAFCGSAACVNFLLDKKANANIKDSAGNTPLQWASSRGHLECIKLLVEKGGVDVNTKDDKNGTPLHKASLFASAECVLYLLNGKADPRAVTTNGETPLHHASAGGNPQCVELLIKADSKVNAVDNDCITPLHQASFSGHSSCVSLLLKKGAKVDPRDIHGISPLHNAASAGYVDCVEQLVRNGENINCVDIEGVTPLHHTCFNGNLQLTKRLIELGAKINMVDEMGETPLHKAAFNGHKEVCEYLLYLDPTMIDCRDSRQSTSLHLAAFNGLLDMVDLLIRYKAQINIKDEEGATPLHKASFNGHSSCAKLLVDKGAPICIVDSQGATPLHKAAFNGRSKCLATLIRSGAELEVKDSQGGTPLHNAAYNGHSDCCRILLKKGANVNAVDTHSSTPLHLASAAGARDTVDVLIQFKARIDAKNFAGKTPLVYAIKKNHSDVARVLIRAGADLDQVSLRSSVDFTKTFGTENHDEIYQIVNKRESSNHEVDELQLALEQQAKEDMEQLAAEKQKLLLIKAAIAQFNSHPKKGIEFIVANGVISEKNPKEVAHFLLTHSELSKQSIGEYIGEGDDFNLQVLHAFVDELNFFGLDFDVALRKYLLTFRLPGEAQKIDRMMEKFASQFYQHNPENKVFVNQDAVYVLAFSVIMLNTDAHNPNIKKKMTKAEFLRNNSGINSGDDLPPDFMENLYDKIVTNEIKMERDGNQANQHVEKKGWLTKQGGRIKTWKKRWFILTANCLLYYKTPQDHEPCGIIPLENVVVTIDPQKKFCFMLHSSQEQMKACKLNSDGTLVQANHAAYFIAAANMAEMDSWVQSIKSNIHSNPNFEQLLKRKAETIRGRGKVSTKPIQNRKQTISGPPPSTTTTTTSTASNNVTSVGSPPNSGSVLNSSGSKPVTFSSTSSPVQQQTSALS
What are the official names of this protein?
Ankyrin repeat, PH and SEC7 domain containing protein secG.
Protein: MTNA_MICAN
Sequence: MTTTTCESNSIYPVRWQDNKVWLIDQTRLPMEYGEVEITSSEAMARAIETMIVRGAPAIGVAAAYGMVLGAQEITTDQKEQFLADLTRIADRLAQTRPTAVNLFWAIERMLKVARESGPEVAVITKNLLETAQNIQKEDVETCRAIGNHGLLALPEQPEKLTILTHCNTGSLATAGYGTALGVIRSAWTAGRLIQVYADETRPRLQGAKLTAWECLREGIPVTVITDSMAAHCMQQKLIDAVIVGADRIAANGDTANKIGTYSLAVVAKAHNLPFYVAAPLSTVDFSLKDGTGIPIEQRDRAEIYQVGTTTLCPRDVNFYNPAFDVTPAALITAIITEKGAVTPAELIFLQDS
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: Y4368_ACAM1
Sequence: MTYSLRILDLPESDRPRERLIAQGAKYLTHAELLAILLGTGQGPGKLSAVGLGQHVLQHFSEHQQDPLTVLRDVNASELTTIQGIGPAKATTILAAIELGKRICQARPPELTVIDDPAVAAAALAGELMWQSQERFAVLLLDVKHRLLGTQVVSIGTATETLAHPRDIFREIIRKGATRAIVAHNHPSGQTDPSPEDLELTQQLLSGAQILGLPLLDHLILGNGDFTSLRQTTSLWNDCPQDL
What are the official names of this protein?
UPF0758 protein AM1_4368.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: PEDB_HYDVU
Sequence: AGEDVSHELEEKEKALANHSE
What is the function of this protein?
Morphogenetically active peptide.  Active in foot development.
What are the official names of this protein?
Pedibin.
Protein: MNMG_CLOB8
Sequence: MAVNYDGGQFDIVVVGAGHAGCEAALASARLGLNTLVCTINLDSIALMPCNPNIGGTAKGHLVREIDALGGEMGINIDNTFIQSRMLNTSKGPAVHSLRAQADKKSYQFRMKRILEEQENLKIRQIEVTELNVENGKVTGVVTKNGAIFKCKAVILATGTYLKGKIIIGEVSYSGGPNGLFPANDLSQSLLDLGVSLRRFKTGTPARINRRSVDFSKMIEQNGDDNIIPFSFMSENIEREQVSCYLTYTNDETRKIIRDNIGRSPIYNGSIKGVGPRYCPSIEDKIMRFPDKPQHQIFIEPEGLDTLEMYVGGFSSSLPEEVQIKMLKTLPGLENVEMMRTAYAIEYDSIDPTQLKPTLEFKDIEGLYGAGQLNGSSGYEEAGAQGLIAGINAALKIKEKEPLILTRSDAYIGVLIDDLVTKGTNEPYRMMTSRAEYRLLLRQDNADFRLTNLGYRVGLVTEERYDKFIKRKQNIENELERLKNLKVTNKKEINEFLISLNSAELRKPITFYELLQRPELDYFDLKQIDSERPELPHDVGEQINILTKYEGYIQSQLEQVAQFKKFEKKLLPKDINYSDIKGLRTEAIQKLSDIRPISIGQATRISGVSPADISVLLIYLEHYYNK
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSB2_SYNY3
Sequence: MNSFVLMATVIREPELRFTKENQTPVCEFLVEFPGMRDDSPKESLKVVGWGNLANTIKETYHPGDRLIIEGRLGMNMIERQEGFKEKRAELTASRISLVDSGNGINPGELSSPPEPEAVDLSNTDDIPF
What are the official names of this protein?
Thylakoid-associated single-stranded DNA-binding protein slr1034, Thylakoid-associated SSB.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RR7_LOTJA
Sequence: MSRRGTAEKKTAKSDPIYRNRLVNMLVNRILKHGKKSLAYQIIYRAMKKIQQKTETNPLSVLRQAIRGVTPDIAVKARRVGGSTHQVPIEIGSTQGKALAIRWLLGASRKRPGRNMAFKLSSELVDAAKGSGDAIRKKEETHRMAEANRAFAHFR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MSRA_MYCTA
Sequence: MTSNQKAILAGGCFWGLQDLIRNQPGVVSTRVGYSGGNIPNATYRNHGTHAEAVEIIFDPTVTDYRTLLEFFFQIHDPTTKDRQGNDRGTSYRSAIFYFDEQQKRIALDTIADVEASGLWPGKVVTEVSPAGDFWEAEPEHQDYLQRYPNGYTCHFVRPGWRLPRRTAESALRASLSPELGT
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: CYB_GALGB
Sequence: MTNIRKHHPLAKMINHSFIDLPTPSNISSWWNFGSLLGLCLVIQITTGLFLAMHYTPDTTTAFSSITHICRDVNYGWIIRYLHANGASMFFICLFMHIGRGLYYGSFTFLETWNIGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYMGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIITALAMVHLLFLHETGSNNPSGISSDPDKIPFHPYYTTKDLLGVILLLLALFSLVLFSPDLLGDPDNYTPVNPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALALSILILILIPFLHTAKQRSMMFRPLSQCLYWMLAADLLTLTWIGGQPVENPFITIGQVASIIYFSTILILMPLTNLLENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: KHSE_BURA4
Sequence: MAVFTAVSDSDLAQWMRHYELGDVLAFRGIPSGIENSNFFLTTTRGEYVLTIFEKLTAEQLPFYLDLMRHLASHGVPVPDPIPRDDGALFGLLHGKPAAIVTKLDGAAELAPGIEHCIEVGQMLARLHLAGRDYARYQPNLRSLPWWQENVPAIVPFVSDAQRALLEGELAHQAAFFASDDYAALPSGPCHCDLFRDNVLFAHAAPGTGHDVRLGGFFDFYFAGCDKWLFDVAVTVNDWCVDLATGVLDVARADALLRAYQTVRPFTAAERRHWSDMLRAGAYRFWVSRLYDFYLPRAAEMLKPHDPGHFERILRERIAHTPALPETHTACN
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the pseudomonas-type ThrB family.
Protein: BIOM_RHOCB
Sequence: MQAIDIGHVTLERDGTGVFSDLTLRLTERRIGIVGRNGAGKSSLIRLITGLVTPQKGRVVVNGVDVAADRAGALGTVGLLFQNPDHQIIFPVVRDEIAFGLEQKGLKRAAALARAEAVLAAQGRADWGDRLCHTLSQGQRQLLCLMSILAMEPDWILFDEPFNALDLPTALSIEARIAGLAQNVVLVTHDPSRLTGFDRILWLEGGRIEADGPPAEVLPRYIAAMQALARAGAC
What is the function of this protein?
Required for biotin uptake under very low (pM) biotin concentrations but not under higher (nM) concentrations.
What are the official names of this protein?
Biotin transport ATP-binding protein BioM, ECF transporter A component BioM.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TAL_BUCAI
Sequence: MNQLSALKQFSIIVADTSDIKSICKYQPEDATTNPSLILQAVSSNTNQNFVDQAVQYAKKKGGLYKDQIINASDKILVDLGIEILKKIPGYISSEVDARLSFSTEASILKAKKIIDLYEEQGISRNRVLIKLAATWECIKAAEELKKDSILCNLTLLFSFAQARACAESNVFLISPFVGRIYDWYISQNLLSKSFLGKDPGVISVCKIYEYYKKYGYKTIIMGASFRNIQQILYLSGCDRLTISPVLLKELESNTAKIDRNLAPPSFISVPPVALSEEEFRWEHNQDAMAVQKLSDGIRNFGKDQLRLEKIFSKKI
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ITR2_SPIOL
Sequence: DKCSPSGAICSGFGPPEQCCSGACVPHPILRIFVCQ
What is the function of this protein?
Trypsin inhibitor.
What are the official names of this protein?
Trypsin inhibitor 2, SOTI II, Trypsin inhibitor II.
What is the protein family that this protein belongs to?
Belongs to the Mirabilis serine proteinase inhibitor family.
Protein: RLMH_SYNS3
Sequence: MNPSRCRIIAIGKVRKSWVQDGIELYRKRLPGLTIVELRDSNPEKEAESIRQTLRRDEWPVMLMEQGETLTSINFSERLRSLGSQRLAFVIGGADGLTAELKALAHWKLSLSPMTFPHELARLLLIEQLFRAQAILQGSPYHRA
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROE_BRUO2
Sequence: MDDKSMARGRKAFFTGFPIRHSRSPLIHGFWLKEQGIDGSYEAVEVKPEDFSSFAASLAANGFAGGNVTIPHKEAAYAAAESLDEAARAIGAVNTLWLENGRLCGGNTDAYGFAANLDASAPGWDKADRALVLGAGGASRAVVHALLSRGVCHVSVVNRTLSRAEELAAHFGARVYAHGWDEAQALVSNAGLIVNTTALGMSGHGEGQDFPIDLTCAPKEAVATDIVYVPLRTAFLNKAEKAGLKTVDGLGMLLHQAVPGFERWFGQRPQVTQALREHILADMAKAGAL
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: ECPR_ECOSM
Sequence: MTWQNDYSRDYEVKNHMECQNRSDKYIWSPHDAYFYKGLSELIVDIDRLIYLSLEKIRKDFVFINLNTDSLTEFINRDNEWLSAVKGKQVVLIAARKSEALANYWYYNSNIRGVVYAGLSRDIRKELAYVINGRFLRKDIKKDKITDREMEIIRMTAQGMLPKSIARIENCSVKTVYTHRRNAEAKLYSKLYKLVQ
What is the function of this protein?
Part of the ecpRABCDE operon, which encodes the E. coli common pilus (ECP).  ECP is found in both commensal and pathogenic strains and plays a dual role in early-stage biofilm development and host cell recognition.  Positively regulates the expression of the ecp operon (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator EcpR.
What is the protein family that this protein belongs to?
Belongs to the EcpR/MatA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XGPT_BRADU
Sequence: MMGGEAPELSAQERAGKAFPVSWDQFHRDCRALTWRLNEVGPFHAVIAITRGGLVPAAIVARELGVRVIDTVCIASYDHNKQGELQVLKGISEAAMKLGGGTGKGLLIVDDLVDTGKTGKLVREMLPDAHFATVYAKPKGRPLVDTYITEVSQDTWIFFPWDTALSYHPPLRDGAA
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi.  To a lesser extent, also acts on hypoxanthine.
What are the official names of this protein?
Xanthine-guanine phosphoribosyltransferase, XGPRT, Xanthine phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: UBC4_YEAST
Sequence: MSSSKRIAKELSDLERDPPTSCSAGPVGDDLYHWQASIMGPADSPYAGGVFFLSIHFPTDYPFKPPKISFTTKIYHPNINANGNICLDILKDQWSPALTLSKVLLSICSLLTDANPDDPLVPEIAHIYKTDRPKYEATAREWTKKYAV
What is the function of this protein?
Catalyzes the covalent attachment of ubiquitin to other proteins (PubMed:17550898).  Mediates the selective degradation of short-lived and abnormal proteins (PubMed:17550898).  Mediates ubiquitination of PEX5 (PubMed:17550898).
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 4, E2 ubiquitin-conjugating enzyme 4, Ubiquitin carrier protein 4, Ubiquitin-protein ligase 4.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: RLMN_ACIBT
Sequence: MSSAVVVSSENLDGQQQSSSTPASPAAEKVNLLGMSRAELEKFFEDIGEKKFRAGQVMKWIHQYFVTDFAEMTNISGKLRAKLEQICEIKAPEVVHRHYSKDGTRKWVFRVGEGSGSLVETVLIPAEDKTGSRKTLCISSQVGCALDCSFCSTGKQGFQRDLTPDEIIGQLWMANYSYMEEVPVAERERSVTNVVMMGMGEPLLNYDAVLSSMHIMLDDFAYGMSKRRVTLSTSGVVPKIDQLAKDIDVALAISLHAPNDELRNELVPINKKYPLAQLIAACQRYIAKDGNESARKHVTIEYVMLEGVNDQPEHAQQLLKLLKNLPSKINLIPFNPFPHAPYGRSSRNRIISFQKTLSDAGFVCTIRQTRGDDIDAACGQLVGQVADRTRRAEQWQKKVAQRQEILRTQG
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM218_XENTR
Sequence: MATTILGVGPGVFIIAVIWMVTLMLTVLLCRASGKARFWTVVVFTLALITTLILVFFPRASQTPAPAKEMQIVDTFFIGRYFLISIMSVIFLGCLFFVFVYHILEPVYAKPIGIH
What is the function of this protein?
May be involved in ciliary biogenesis or function.
What are the official names of this protein?
Transmembrane protein 218.
What is the protein family that this protein belongs to?
Belongs to the TMEM218 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell projection, cilium. Note=Localizes at the transition zone, a region between the basal body and the ciliary axoneme.
Protein: UNG_ECOL5
Sequence: MANELTWHDVLAEEKQQPYFLNTLQTVASERQSGVTIYPPQKDVFNAFRFTELGDVKVVILGQDPYHGPGQAHGLAFSVRPGIATPPSLLNMYKELENTIPGFTRPNHGYLESWARQGVLLLNTVLTVRAGQAHSHASLGWETFTDKVISLINQHRKGVVFLLWGSHAQKKGAIIDKQRHHVLKAPHPSPLSAHRGFFGCNHFVLANQWLEQRGETPIDWMPVLPAESE
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYG_STRPN
Sequence: MSELISVVVPIYNTGKYLVECVEHILKQTYQNIEIILVDDGSTDNSGEICDAFMMQDNRVRVLHQENKGGAAQAKNMGISVAKGEYITIVDSDDIVKENMIETLYQQVQEKDADVVIGNYYNYDESDGNFYFYVTGQDFCVEELAIQEIMNRQAGDWKFNSSAFILPTFKLIKKELFNEVHFSNGRRFDDEATMHRFYLLASKIVFINDNLYLYRRRSGSIMRTEFDLSWARDIVEVFSKKISDCVLAGLDVSVLRIRFVNLLKDYKQTLEYHQLTDTEEYKDICFRLKLFFDAEQRNGKS
What is the function of this protein?
Also catalyzes the fourth step in glycosylation of the serine-rich repeat protein PsrP in this bacteria.  Can transfer the sugar from UDP-glucose (and much less well from UDP-galactose) to the terminal sugar moiety of PsrP-GlcNAc-Glc-Gal or of PsrP-GlcNAc-Glc-Glc.
What are the official names of this protein?
Glycosyltransferase GlyG, PsrP glycosyltransferase GlyG.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
Protein: RS15_ANADF
Sequence: MALVQERKQELVTKYKRHEKDTGSPEVQVALLTERIAYLTEHFKTHKKDHHSRRGLLKLVGQRRRLLDYLRSIDQGRYKTLIDQLGIRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.