PharMolix/UniProtQA huggingface dataset:
Protein: ILVE_STAEQ
Sequence: MSEKVKFEKRESLKEKPDTANLGFGQYFTDYMLSVDYDADQGWHDMKIVPYAPFEISPAAQGLHYGQAVFEGLKAYKHNGEVVLFRPDQNFKRINNSLARLEMPEVDEEALLEGLKQLVDVERDWVPEGEGQSLYIRPFVFATEGILGVRSSHQYKLLIILSPSGAYYGGDTLKSTKIYVEDEYVRAVRGGVGFAKVAGNYAASLLAQTNANKLGYDQVLWLDGVEQKYVEEVGSMNIFFVENGKVVTPALNGSILPGITRKSIIQLAEDLGYEVEERRVSIEELFNAYDKGELTEVFGSGTAAVISPVGTLRYEDREIVINNNEPGKITQKLYDTYTGIQSGKLEDKYGWRVEVPKY
What is the function of this protein?
Acts on leucine, isoleucine and valine.
What are the official names of this protein?
Probable branched-chain-amino-acid aminotransferase, BCAT.
What is the protein family that this protein belongs to?
Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
Protein: PYRD_ECOLC
Sequence: MYYPFVRKALFQLDPERAHEFTFQQLRRITGTPFEALVRQKVPAKPVNCMGLTFKNPLGLAAGLDKDGECIDALGAMGFGSIEIGTVTPRPQPGNDKPRLFRLVDAEGLINRMGFNNLGVDNLVENVKKAHYDGVLGINIGKNKDTPVEQGKDDYLICMEKIYAYAGYIAINISSPNTPGLRTLQYGEALDDLLTAIKNKQNDLQAMHHKYVPIAVKIAPDLSEEELIQVADSLVRHNIDGVIATNTTLDRSLVQGMKNCDQTGGLSGRPLQLKSTEIIRRLSLELNGRLPIIGVGGIDSVIAAREKIAAGASLVQIYSGFIFKGPPLIKEIVTHI
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL32_SINMW
Sequence: MAVPKRKTSPSKRGMRRSADALKAPTYIEDKNSGELRRPHHIDLKTGMYRGRQVLTPKESA
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: PSBP_FRIAG
Sequence: MASSACFLLHHAPSTPATTSRTPSHRLVPTIKPSQLICRAQKSSDTDENSSTAVSRRLALTILIGSAAVGTKIAPANAAYGEAANVFGKAKTNTDFLPYTGDGFNLLIPAKWNPSKEVEFPGQVLRYEDNFDVTSNVSVTVTPTSKKSITDYGTPEEFLSTVDYLLGKQAYSGKTASEGGFDPDSVATANILEVSTPVVGGKQYYNISVLTRTADGDEGGKHHVISATVTDGKLYICKAQAGDKRWFKGAKKFVESTTTSFNVA
What is the function of this protein?
May be involved in the regulation of photosystem II.
What are the official names of this protein?
Oxygen-evolving enhancer protein 2, chloroplastic, OEE2, 23 kDa subunit of oxygen evolving system of photosystem II, 23 kDa thylakoid membrane protein, OEC 23 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the psbP family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane. Note=Associated with the photosystem II complex.
Protein: MRAY_SHEB5
Sequence: MLVYLAEYLTRFHTGFNVFSYVTFRAILGLLTALVFSLWFGPKLIERLQLLQIGQVVRNDGPESHFSKRGTPTMGGLLILAAIFISVLLWGDLGSRYVWVMLFVLGSFGLIGFIDDYRKVVRKDTKGLIARWKYILQSLAALLIAFFLYATAANPGETQLVVPFFKDVMPQLGAVFIVLAYFTIVGSSNAVNLTDGLDGLAIMPTVMVAAAFALIAYLSGHAQFANYLHIPHLPGSGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLSLGAALGTIAVLVRQEILLVIMGGVFVMETLSVILQVGSYKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISIFLVLLGLATLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SCUB1_MOUSE
Sequence: MGAAAVRWHLYLLLALGARGRLVGGSGLPGAVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGRQCEDIDECENDYYNGGCVHDCINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPMCGCHQKYALHADGRTCIEKDEAAIERSQFNATSVADVDKRVKRRLLMETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLMNNGGCDHFCRNTVGSFECGCQKGHKLLTDERTCQDIDECSFERTCDHICINSPGSFQCLCRRGYTLYGTTHCGDVDECSMNNGSCEQGCVNTKGSYECVCPPGRRLHWNQKDCVEMNGCLSRSKASAQAQLSCGKVGGVENCFLSCLGHSLFMPDSESSYILSCGVPGLQGKTLPKRNGTSSSTGPGCSDAPTTPIRQKARFKIRDAKCHLQPRSQERAKDTLRHPLLDNCHVTFVTLKCDSSKKRRRGRKSPSKEVSHITAEFEVEMKVDEASGTCEADCMRKRAEQSLQAAIKILRKSIGRNQFYVQVLGTEYEVAQRPAKALEGTGTCGIGQILQDGKCVPCAPGTYFSGDPGQCMPCVSGTYQDMEGQLSCTPCPSSEGLGLAGARNVSECGGQCSPGYFSADGFKPCQACPVGTYQPEPGRTGCFPCGGGLLTKHTGTASFQDCEAKVHCSPGHHYNTTTHRCIRCPVGTYQPEFGQNHCISCPGNTSTDFDGSTNVTHCKNQHCGGELGDYTGYIESPNYPGDYPANAECVWHIAPPPKRRILIVVPEIFLPIEDECGDVLVMRKSASPTSVTTYETCQTYERPIAFTSRSRKLWIQFKSNEANSGKGFQVPYVTYDEDYQQLIEDIVRDGRLYASENHQEILKDKKLIKALFDVLAHPQNYFKYTAQESKEMFPRSFIKLLRSKVSRFLRPYK
What is the function of this protein?
Could function as an adhesive molecule and its matrix bound and soluble fragments may play a critical role in vascular biology.
What are the official names of this protein?
Signal peptide, CUB and EGF-like domain-containing protein 1.
What are the subcellular locations of this protein?
Secreted. Cell membrane; Peripheral membrane protein.
Protein: STMP1_MOUSE
Sequence: MLQFLLGFTLGNVVGMYLAQNYEMPNLAKKLEEIKKDLEAKKKPPSS
What is the function of this protein?
Microprotein involved in mitochondrial respiratory chain complex III (ubiquinol-cytochrome c oxidoreductase) and complex IV (mitochondrial cytochrome c oxidase complex) assembly (PubMed:35101990).  Required for the formation of mitochondrial supercomplexes (SCs) (PubMed:35101990).  Also required for the activation of the NLRP3 inflammasome (PubMed:31836654).
What are the official names of this protein?
Short transmembrane mitochondrial protein 1, Mitochondrial micropeptide-47, Mm47, Protein mitolamban.
What is the protein family that this protein belongs to?
Belongs to the STMP1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein. Mitochondrion outer membrane; Single-pass membrane protein. Mitochondrion intermembrane space.
Protein: CAS9_STRTR
Sequence: MLFNKCIIISINLDFSNKEKCMTKPYSIGLDIGTNSVGWAVITDNYKVPSKKMKVLGNTSKKYIKKNLLGVLLFDSGITAEGRRLKRTARRRYTRRRNRILYLQEIFSTEMATLDDAFFQRLDDSFLVPDDKRDSKYPIFGNLVEEKVYHDEFPTIYHLRKYLADSTKKADLRLVYLALAHMIKYRGHFLIEGEFNSKNNDIQKNFQDFLDTYNAIFESDLSLENSKQLEEIVKDKISKLEKKDRILKLFPGEKNSGIFSEFLKLIVGNQADFRKCFNLDEKASLHFSKESYDEDLETLLGYIGDDYSDVFLKAKKLYDAILLSGFLTVTDNETEAPLSSAMIKRYNEHKEDLALLKEYIRNISLKTYNEVFKDDTKNGYAGYIDGKTNQEDFYVYLKNLLAEFEGADYFLEKIDREDFLRKQRTFDNGSIPYQIHLQEMRAILDKQAKFYPFLAKNKERIEKILTFRIPYYVGPLARGNSDFAWSIRKRNEKITPWNFEDVIDKESSAEAFINRMTSFDLYLPEEKVLPKHSLLYETFNVYNELTKVRFIAESMRDYQFLDSKQKKDIVRLYFKDKRKVTDKDIIEYLHAIYGYDGIELKGIEKQFNSSLSTYHDLLNIINDKEFLDDSSNEAIIEEIIHTLTIFEDREMIKQRLSKFENIFDKSVLKKLSRRHYTGWGKLSAKLINGIRDEKSGNTILDYLIDDGISNRNFMQLIHDDALSFKKKIQKAQIIGDEDKGNIKEVVKSLPGSPAIKKGILQSIKIVDELVKVMGGRKPESIVVEMARENQYTNQGKSNSQQRLKRLEKSLKELGSKILKENIPAKLSKIDNNALQNDRLYLYYLQNGKDMYTGDDLDIDRLSNYDIDHIIPQAFLKDNSIDNKVLVSSASNRGKSDDFPSLEVVKKRKTFWYQLLKSKLISQRKFDNLTKAERGGLLPEDKAGFIQRQLVETRQITKHVARLLDEKFNNKKDENNRAVRTVKIITLKSTLVSQFRKDFELYKVREINDFHHAHDAYLNAVIASALLKKYPKLEPEFVYGDYPKYNSFRERKSATEKVYFYSNIMNIFKKSISLADGRVIERPLIEVNEETGESVWNKESDLATVRRVLSYPQVNVVKKVEEQNHGLDRGKPKGLFNANLSSKPKPNSNENLVGAKEYLDPKKYGGYAGISNSFAVLVKGTIEKGAKKKITNVLEFQGISILDRINYRKDKLNFLLEKGYKDIELIIELPKYSLFELSDGSRRMLASILSTNNKRGEIHKGNQIFLSQKFVKLLYHAKRISNTINENHRKYVENHKKEFEELFYYILEFNENYVGAKKNGKLLNSAFQSWQNHSIDELCSSFIGPTGSERKGLFELTSRGSAADFEFLGVKIPRYRDYTPSSLLKDATLIHQSVTGLYETRIDLAKLGEG
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and Cas9.  The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA (Probable).  Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer yielding blunt ends; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA).  Cas9 recognizes a 3'-G-rich protospacer adjacent motif (PAM, TGGTG in this organism) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs.  PAM recognition is also required for catalytic activity.  When the CRISPR3/cas system consisting of cas9-cas1-cas2-csn2-CRISPR3 or just cas9-CRISPR3 is expressed in E. coli it prevents plasmids homologous to spacers 1 or 2 from transforming.
What are the official names of this protein?
CRISPR-associated endonuclease Cas9, St-Cas9.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated protein Cas9 family. Subtype II-A subfamily.
Protein: AUSS_EMENI
Sequence: MSIRERLLATVSKYIAAYNEFDPSAMKTVRTPTCLTHGVAPTCKFTQSMEEHTRHMMLSRGVFRSVNASIVDDNITVVDEVSRQVVVKVKIRCETTVGPYENEAMFIMAMNEEGALVDEIFQFLDTARFRQFQGRLEEAQ
What is the function of this protein?
Part of the gene cluster B that mediates the biosynthesis of austinol and dehydroaustinol, two fungal meroterpenoids (PubMed:22329759).  The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid by the polyketide synthase ausA (PubMed:22329759).  3,5-dimethylorsellinic acid is then prenylated by the polyprenyl transferase ausN (PubMed:22329759).  Further epoxidation by the FAD-dependent monooxygenase ausM and cyclization by the probable terpene cyclase ausL lead to the formation of protoaustinoid A (PubMed:22329759).  Protoaustinoid A is then oxidized to spiro-lactone preaustinoid A3 by the combined action of the FAD-binding monooxygenases ausB and ausC, and the dioxygenase ausE (PubMed:22329759, PubMed:23865690).  Acid-catalyzed keto-rearrangement and ring contraction of the tetraketide portion of preaustinoid A3 by ausJ lead to the formation of preaustinoid A4 (PubMed:22329759).  The aldo-keto reductase ausK, with the help of ausH, is involved in the next step by transforming preaustinoid A4 into isoaustinone which is in turn hydroxylated by the P450 monooxygenase ausI to form austinolide (PubMed:22329759).  Finally, the cytochrome P450 monooxygenase ausG modifies austinolide to austinol (PubMed:22329759).  Austinol can be further modified to dehydroaustinol which forms a diffusible complex with diorcinol that initiates conidiation (PubMed:22234162, PubMed:22329759).  Due to genetic rearrangements of the clusters and the subsequent loss of some enzymes, the end products of the Emericella nidulans austinoid biosynthesis clusters are austinol and dehydroaustinol, even if additional enzymes, such as the O-acetyltransferase ausQ and the cytochrome P450 monooxygenase ausR are still functional (PubMed:29076725).  AusS is necessary for austinoids production and may play a possible function as a regulator (By similarity).
What are the official names of this protein?
Austinoid biosynthesis clusters protein S.
What is the protein family that this protein belongs to?
Belongs to the trt14 isomerase family.
Protein: CSN5_MOUSE
Sequence: MAASGSGMAQKTWELANNMQEAQSIDEIYKYDKKQQQEILAAKPWTKDHHYFKYCKISALALLKMVMHARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQAAAYEYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGKVNLGAFRTYPKGYKPPDEGPSEYQTIPLNKIEDFGVHCKQYYALEVSYFKSSLDRKLLELLWNKYWVNTLSSSSLLTNADYTTGQVFDLSEKLEQSEAQLGRGSFMLGLETHDRKSEDKLAKATRDSCKTTIEAIHGLMSQVIKDKLFNQINVA
What is the function of this protein?
Probable protease subunit of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes.  The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2.  Promotes the proteasomal degradation of BRSK2.  The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8, possibly via its association with CK2 and PKD kinases.  CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.  In the complex, it probably acts as the catalytic center that mediates the cleavage of Nedd8 from cullins.  It however has no metalloprotease activity by itself and requires the other subunits of the CSN complex.  Interacts directly with a large number of proteins that are regulated by the CSN complex, confirming a key role in the complex.
What are the official names of this protein?
COP9 signalosome complex subunit 5, SGN5, Signalosome subunit 5, Jun activation domain-binding protein 1, Kip1 C-terminus-interacting protein 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M67A family. CSN5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Cytoplasm, perinuclear region. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Note=Nuclear localization is diminished in the presence of IFIT3.
Protein: RLMD_EDWI9
Sequence: MAQFYTPGRRTATRKILIVTATDLDAFGQGVAREQGKTLFISGLLPGEQAEVILSEEKRHFARGRVTRLISHSPQRVAPRCPHAGVCGGCQQQHAAIALQQQSKSQALQRLMARETGVDIAPQVIAGEPYGYRRRARFGLQFNVKTQRVVLGFRQAASNDLVALKACPVLAPALEALLLPLGECLSALRARRRLGHLELVLADNGPLMVLRHLDPLSLSDREALSAFARQRGLTLYLSDGGAPQRLLGEAPYYQIDGSRLDFNPQDFIQVNAAVNAQMVGQALAWLDVRADERVLDLFCGMGNFTLPLARLALRVVGVEGVPGLVATAQNNARNNGLSNVEFFHQNLEEDVTRQAWASQGFDKILLDPARAGAPGVMQHIVRLAPRRVVYVSCNPTTLARDSQTLLQGGYRLTRLCMLDMFPHTGHLESMALFESAAQ
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: ENO_NATPD
Sequence: MTLITEVRLRKILDSRGNPTVEAEVRTENGGFGRGAAPSGASTGEYEAVERPAEEAIAQARELAVPRIEGQVYAGDQRGVDNALHGADGTDDFSEIGANSAVAISMAAAKAAADVLGAPLYQHLGGAFRGRDFPVPLGNVIGGGEHAADATHIQEFLAAPVGAPSVADAVFANAKVHGEVQRQLDERGVPAAKGDEGAWAPSIDDSEAFEIMEEAIAAVEDEVGFEIRFGLDVAGAELYEDGVYHYGDETRSPDEQVAYIADLVEEYNLVYVEDPLDEDDFSGFAELTERVGDRTLICGDDLFVTNTERLQRGIDDGAANSILIKPNQIGTLSDAFDAIELATRNGYDPVVSHRSGETEDTTIAHLAVATDAPFIKTGAVGGERTAKLNELIRIEANA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: YIDD_PHOV8
Sequence: MKKILSYLLLLPVYFYRGYISPMTPPSCRFVPTCSEYAIEAIKKHGPFKGLYLAVRRILRCHPWGGSGYDPVP
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RHAD_LISMO
Sequence: MTKDIMDAVFIKEMAKTTSNLYRLGWDERNGGNITYLLDEKEVAEYLDVKQIIRTIPMDFDGKKLAGKYFLVTGSGKYFKNVEEAPAVNLGVIQVSEDGKAVHLLWGYTDGGLPTSELPAHFMSHIARLSVDPENRVVMHCHATHLLAMTFTHELTERAFTRTLWQMCTECLVVFPEGVGIIPWLVPGTNEIGEATSEKMKENRLIVWPHHGIYGAGQSMDETFGLIETAEKAAEVYTIVMSQGGIKQAITDEQLKALGERFGVEAKAGYLNN
What is the function of this protein?
Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.
What are the official names of this protein?
Rhamnulose-1-phosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. RhaD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAE_BACSU
Sequence: MKQLKWRTVNPEETKAIAKLTAAFAKPGDVLTLEGDLGAGKTTFTKGFAEGLGITRIVNSPTFTIIKEYNDGVLPLYHMDVYRMEDESEDLGLDEYFHGQGVCLVEWAHLIEEQLPQERLQIVIKRAGDDEREITFTAVGNRYEMLCEELSRHDNISN
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB; this reaction does not require ATP in vitro.  TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.  Displays ATPase activity in vitro, which is modulated by the oligomeric status of the protein.
What are the official names of this protein?
tRNA threonylcarbamoyladenosine biosynthesis protein TsaE, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaE.
What is the protein family that this protein belongs to?
Belongs to the TsaE family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localized predominantly at the cell poles and at the periphery of the bacterium.
Protein: SPC25_DROOR
Sequence: MAIIMAESSYERRIKALYEKQIRMEALEGKFIKKVFKFNSVLLDIKETSARHQRKVGKMQKVVTERREELGRRVTFMGHLTQEVEAIKLRNLAMKDQIKQQKMLNNQRKNEIMERIHTLSKTTGTYVNQEALPARVKGVTVIPGDRRNQLIPFDLNATDDEGLNSLCQHLESLNVDVSQWQQLVSLAMDVALGARAPTTPPKEAANCKSIIEIDLTSPTS
What is the function of this protein?
Acts as a component of the essential kinetochore-associated Ndc80 complex, which is required for chromosome segregation and spindle checkpoint activity during meiosis and mitosis.  Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.  Participates in SAC signaling that responds specifically to disruptions in spindle microtubule dynamics.  The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules.
What are the official names of this protein?
Kinetochore protein Spc25.
What is the protein family that this protein belongs to?
Belongs to the SPC25 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore.
Protein: PYRB_METCA
Sequence: MSVTAAADIQLTASGRLRHFLTIEGLSRELLTRIMDTAESFAGVTAQNVKKVPLLRGKTVVNLFFENSTRTRTTFELAAKRLSADVLNINIATSATSKGESLLDTIRNLEAMHVDMFVVRHAQSGAAHFIARHVAPHISVLNAGDGRHAHPTQAMLDVFTIRRAKGGFAGLKVAIVGDILHSRVARSEIWALNTLGVDEVRVVAPKTLLPAHVEALGVVPYHDLNEGLRDVDVVIMLRLQLERMGSAFIPSEHEYFQRFGLTEKRLEKARPDVIVMHPGPINRGIEIDSAIADGPRSVILQQVTHGIAVRMAVMSMAMHAGPDLEVPV
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: RL35_XANOR
Sequence: MPKIKTNRAAAKRFRKTASGKYKCGHANRSHILTKKATKRKRNLRQTNHVRAEDAGRLDRMLPYL
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: MLAC_ECOLI
Sequence: MFKRLMMVALLVIAPLSAATAADQTNPYKLMDEAAQKTFDRLKNEQPQIRANPDYLRTIVDQELLPYVQVKYAGALVLGQYYKSATPAQREAYFAAFREYLKQAYGQALAMYHGQTYQIAPEQPLGDKTIVPIRVTIIDPNGRPPVRLDFQWRKNSQTGNWQAYDMIAEGVSMITTKQNEWGTLLRTKGIDGLTAQLKSISQQKITLEEKK
What is the function of this protein?
Involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane.  May transfer phospholipid across the periplasmic space and deliver it to the MlaFEDB complex at the inner membrane.
What are the official names of this protein?
Intermembrane phospholipid transport system binding protein MlaC.
What is the protein family that this protein belongs to?
Belongs to the MlaC/ttg2D family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RARA_COXBU
Sequence: MLSNNDFIPLATRMRPGCLEEFVGQSHLLGKDKPLFRAIEKGKLHSMILWGPPGSGKTTLAEIIAQKAGARVESISAVLAGVKDIRDVVERAERHKGQATILFVDEVHGFNKSQQDAFLPHVEKGTITLIGATTENPSFQLNNALLSRTRVYVLKQLTEADLLSILENALANEERGLGKKALEIPEPLRRRIVQFADGDARQCLNLLEIIADFALEENGRFVVDDGLIDKVLTEGLRRFDKRGEAFYDQISALHKSVRGSDPDASLYWLSRLLDGGCDPFYVARRVVRMASEDIGNADPRALQLALDAWETFERLGTPEGELAIAQAVVYCACAAKSNAVYKAFNAASREVKSTGSLEVPLYLRNAPTRLMKSLDYGKDYRYAHDESDGFAAGVDYLPESLIGRRYYFPINRGLEIKIKEKLEYYRKLNEQHKTTEDSKN
What is the function of this protein?
DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.
What are the official names of this protein?
Replication-associated recombination protein A.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
Protein: EFTU_LEVBA
Sequence: MAEKEHYERTKPHVNIGTIGHIDHGKTTLTAAITKVLADKGLAKAEDYADIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYIKNMITGAAQMDGAILVVAATDGPMPQTREHILLARQVGVDYIVVFLNKTDLVDDDELVDLVEMEVRELLSEYDYPGDDIPVIRGSALKALEGDEEQEKVILHLMDVVDDYIPTPERENDKPFLMPVEDVFTITGRGTVASGRIDRGTVKVGDEVEVVGLHEDVLKTTVTGLEMFRKTLDLGEAGDNVGALLRGVNREQVVRGQVLAQPGSIQTHEKFKGEVYILSKEEGGRHTPFFSNYRPQFYFHTTDITGVIELPDGVEMVMPGDNVTFTVELIQPAAIEKGTKFTVREGGHTVGAGTVTEIDD
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WOR1_GIBM7
Sequence: MSGTTQLRPTYHGYVRDTTDALIIFEACLAGQLLHVPRRPHDRERQNVIKSGSIFVYEEHASGIKRWTDSITWSPSRIMGNYLVYRQLEKPFAPGEKKRAKGKGGKSTTQSGGISKPRQRNALPFQQGLEQGNEYPSVPSDEDRQLVGSLVDSYDFKEQGLVKKTISITYNGVPHHLISYYTVEDVKAGLLTSPADDQGLRGVVPRAELTNGQNFRAPIEESIGGAYMPGMRHSAGFPHPSAYPTLLHQPQMHQPQVHQPLAHQPQVHQPLAHQPQVHQPLAHQPQVHQQYVHQPQAHQPYMHQPQVHLNGYQPSYGDGQWWKYLGGT
What is the function of this protein?
Global transcriptional regulator of transcription that impacts, but is not absolutely required for secondary metabolism and pathogenicity on maize.  Regulates synthesis of multiple secondary metabolites, including fumonisins and fusarins.
What are the official names of this protein?
Global transcription regulator sge1.
What is the protein family that this protein belongs to?
Belongs to the MIT1/WOR1 family.
What are the subcellular locations of this protein?
Nucleus.