PharMolix/UniProtQA huggingface dataset:
Protein: YIDD_NEIM0
Sequence: MNFLLSKLLLGLIRFYQYCISPLIPPRCRYTPTCSQYAVEAVKKYGAFKGGRLAIKRIARCHPFGGHGHDPVP
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: STP4_ARATH
Sequence: MAGGFVSQTPGVRNYNYKLTPKVFVTCFIGAFGGLIFGYDLGISGGVTSMEPFLEEFFPYVYKKMKSAHENEYCRFDSQLLTLFTSSLYVAALVSSLFASTITRVFGRKWSMFLGGFTFFIGSAFNGFAQNIAMLLIGRILLGFGVGFANQSVPVYLSEMAPPNLRGAFNNGFQVAIIFGIVVATIINYFTAQMKGNIGWRISLGLACVPAVMIMIGALILPDTPNSLIERGYTEEAKEMLQSIRGTNEVDEEFQDLIDASEESKQVKHPWKNIMLPRYRPQLIMTCFIPFFQQLTGINVITFYAPVLFQTLGFGSKASLLSAMVTGIIELLCTFVSVFTVDRFGRRILFLQGGIQMLVSQIAIGAMIGVKFGVAGTGNIGKSDANLIVALICIYVAGFAWSWGPLGWLVPSEISPLEIRSAAQAINVSVNMFFTFLVAQLFLTMLCHMKFGLFFFFAFFVVIMTIFIYLMLPETKNVPIEEMNRVWKAHWFWGKFIPDEAVNMGAAEMQQKSV
What is the function of this protein?
Mediates an active uptake of hexoses, probably by sugar/hydrogen symport.  Can transport glucose, methylglucose, galactose, xylose and mannose, but not fructose.
What are the official names of this protein?
Sugar transport protein 4, Hexose transporter 4.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSD_GEOSW
Sequence: MLKWLYRLMIELTNHSLSSKMIAIFTKSRLSALLIPSYAKIYDINQEEMEKNLKNYETLQQLFIRKLKAGTRPIDQTKNSVISPVDAIIEDIGVIRENSEIVVKGKTYSIAEMLGSDEAAKKYLNGLFIILYLSPSHYHRIHSPISGVVQKQWALGKKSYPVNRLGLKYGKRPLSKNYRMITEVAANGKHIAIVKIGAMFVNSIELTHASEHLTKGQEIAYFSFGSTVVLLFEKDSIELDERIVAPMGVKVGERIGYLK
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PYEL1_METAC
Sequence: MKNIEDLIQKAVELQNNGLVTGQIADELNVSRETVTWLLTRSKKEVAVPAPKDISVNWSSIGKSATRLHYISLALCDMVLETLEKTNAEVDVVVGVAASGIPLASMMANELGADFALYHSRKGQDVVQPGQKGTISRNFGSVVGKNCVIVDDVITTGSTTMEVIEQLREMGAKPRVVAVLVDKKGADTIANVPIQSLVRIVRVD
What are the official names of this protein?
PyrE-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
Protein: RSMG_ACIBY
Sequence: MHPFFQELQQGSQKLGLSLSDEALTLLLKYQDALVLWNKAYNLTAIRDPKEMLVKHLLDSLSILKDLPAGRLLDVGTGGGMPGMIIALCQPERSCVLLDSNGKKIRFLKQFIADLKLKNVIAVQTRVENQDTIDELGQFDVITSRAFASLTDFVEAARPYLHEQSIIAAMKGLIPVEEMEELKQEFSCKVIELHVPRLDEQRHLLLLQRI
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA1_STAAR
Sequence: MGFLSKILDGNNKEIKQLGKLADKVIALEEKTAILTDEEIRNKTKQFQTELADIDNVKKQNDYLDKILPEAYALVREGSKRVFNMTPYKVQIMGGIAIHKGDIAEMRTGEGKTLTATMPTYLNALAGRGVHVITVNEYLSSVQSEEMAELYNFLGLTVGLNLNSKTTEEKREAYAQDITYSTNNELGFDYLRDNMVNYSEDRVMRPLHFAIIDEVDSILIDEARTPLIISGEAEKSTSLYTQANVFAKMLKQDEDYKYDEKTKSVHLTEQGADKAERMFKVENLYDVQNVDVISHINTALRAHVTLQRDVDYMVVDGEVLIVDQFTGRTMPGRRFSEGLHQAIEAKEGVQIQNESKTMASITFQNYFRMYNKLAGMTGTAKTEEEEFRNIYNMTVTQIPTNKPVQRNDKSDLIYISQKGKFDAVVEDVVEKHKAGQPVLLGTVAVETSEYISNLLKKRGIRHDVLNAKNHEREAEIVAGAGQKGAVTIATNMAGRGTDIKLGEGVEELGGLAVIGTERHESRRIDDQLRGRSGRQGDKGDSRFYLSLQDELMIRFGSERLQKMMSRLGLDDSTPIESKMVSRAVESAQKRVEGNNFDARKRILEYDEVLRKQREIIYNERNSIIDEEDSSQVVDAMLRSTLQRSINYYINTADDEPEYQPFIDYINDIFLQEGDITEDDIKGKDAEDIFEVVWAKIEAAYQSQKDILEEQMNEFERMILLRSIDSHWTDHIDTMDQLRQGIHLRSYAQQNPLRDYQNEGHELFDIMMQNIEEDTCKFILKSVVQVEDNIEREKTTEFGEAKHVSAEDGKEKVKPKPIVKGDQVGRNDDCPCGSGKKFKNCHGK
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 1.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: DAPE_GLAP5
Sequence: MQNQIISLSRSLIQRKSISPNDEGCQQLIAERLQAVRFKLEWLPFGDTLNLWATHGEGEPCLAFAGHTDVVPEGDESQWTYPPFSAEIVDDMLYGRGAADMKGSLAAMVIACETFVKNNPNHQGKIALLITSDEEAAAKDGTVKVVETLMQRQEPIHYCVVGEPSSTKQLGDVVKNGRRGSITANLYIEGIQGHVAYPHLAENPVHTALPFLSELTAYQWDNGNEFFPPTSLQIANIKAGTGSNNVIPGELYVQFNLRYCTEVNDEIIKTKVAEMLRKYGLKHRIEWNLSGKPFLADNGKLVQATIQAVENVTQITPKLDTGGGTSDGRFIALMGAEVVEFGPINQTIHKVNECVNVNDLGKCGEVYYQILCSVIPN
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: NUSG_STAA8
Sequence: MSEEVGAKRWYAVHTYSGYENKVKKNLEKRVESMNMTEQIFRVVIPEEEETQVKDGKAKTTVKKTFPGYVLVELIMTDESWYVVRNTPGVTGFVGSAGAGSKPNPLLPEEVRFILKQMGLKEKTIDVELEVGEQVRIKSGPFANQVGEVQEIETDKFKLTVLVDMFGRETPVEVEFDQIEKL
What is the function of this protein?
Participates in transcription elongation, termination and antitermination.
What are the official names of this protein?
Transcription termination/antitermination protein NusG.
What is the protein family that this protein belongs to?
Belongs to the NusG family.
Protein: COG4_HUMAN
Sequence: MADLDSPPKLSGVQQPSEGVGGGRCSEISAELIRSLTELQELEAVYERLCGEEKVVERELDALLEQQNTIESKMVTLHRMGPNLQLIEGDAKQLAGMITFTCNLAENVSSKVRQLDLAKNRLYQAIQRADDILDLKFCMDGVQTALRSEDYEQAAAHTHRYLCLDKSVIELSRQGKEGSMIDANLKLLQEAEQRLKAIVAEKFAIATKEGDLPQVERFFKIFPLLGLHEEGLRKFSEYLCKQVASKAEENLLMVLGTDMSDRRAAVIFADTLTLLFEGIARIVETHQPIVETYYGPGRLYTLIKYLQVECDRQVEKVVDKFIKQRDYHQQFRHVQNNLMRNSTTEKIEPRELDPILTEVTLMNARSELYLRFLKKRISSDFEVGDSMASEEVKQEHQKCLDKLLNNCLLSCTMQELIGLYVTMEEYFMRETVNKAVALDTYEKGQLTSSMVDDVFYIVKKCIGRALSSSSIDCLCAMINLATTELESDFRDVLCNKLRMGFPATTFQDIQRGVTSAVNIMHSSLQQGKFDTKGIESTDEAKMSFLVTLNNVEVCSENISTLKKTLESDCTKLFSQGIGGEQAQAKFDSCLSDLAAVSNKFRDLLQEGLTELNSTAIKPQVQPWINSFFSVSHNIEEEEFNDYEANDPWVQQFILNLEQQMAEFKASLSPVIYDSLTGLMTSLVAVELEKVVLKSTFNRLGGLQFDKELRSLIAYLTTVTTWTIRDKFARLSQMATILNLERVTEILDYWGPNSGPLTWRLTPAEVRQVLALRIDFRSEDIKRLRL
What is the function of this protein?
Required for normal Golgi function (PubMed:19536132, PubMed:30290151).  Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1 (PubMed:19536132).
What are the official names of this protein?
Conserved oligomeric Golgi complex subunit 4, COG complex subunit 4, Component of oligomeric Golgi complex 4.
What is the protein family that this protein belongs to?
Belongs to the COG4 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Mosty cytosolic, with about 5% membrane-bound.
Protein: RF3_STRPZ
Sequence: MSLTEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVKGKKSGTFAKSDWMDIEKQRGISVTSSVMQFDYAGKRVNILDTPGHEDFSEDTYRTLMAVDAAVMVVDSAKGIEAQTKKLFEVVKHRNIPVFTFINKLDRDGREPLELLEELEEVLGIASYPMNWPIGMGRAFEGLYDLHNKRLELYKGDERFASIEDGDQLFANNPFYEQVKEDIELLQEAGNDFSEQAILDGDLTPVFFGSALTNFGVQTFLDTFLEFAPEPHGHKTTEGNVVDPLTKDFSGFVFKIQANMDPKHRDRIAFVRIVSGEFERGMGVNLTRTGKGAKLSNVTQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVSPKNVMKQKSFHKGIEQLVQEGAIQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAEVVMTPMGKKTVRWISEDDLDQHMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDVTLEEKM
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRPK2_MOUSE
Sequence: MSVNSEKSSSSERPEPQQKAPLVPPPPPPPPPPPLPDPAPPEPEEEILGSDDEEQEDPADYCKGGYHPVKIGDLFNGRYHVIRKLGWGHFSTVWLCWDMQGKRFVAMKVVKSAQHYTETALDEIKLLKCVRESDPSDPNKDMVVQLIDDFKISGMNGIHVCMVFEVLGHHLLKWIIKSNYQGLPVRCVKSIIRQVLQGLDYLHSKCKIIHTDIKPENILMCVDDAYVRRMAAEATEWQKAGAPPPSGSAVSTAPQQKPIGKISKNKKKKLKKKQKRQAELLEKRLQEIEELEREAERKILEENITSAEASGEQDGEYQPEVTLKAADLEDTTEEETAKDNGEVEDQEEKEDAEKENAEKDEDDVEQELANLDPTWVESPKANGHIENGPFSLEQQLEDEEDDEDDCANPEEYNLDEPNAESDYTYSSSYEQFNGELPNGQHKTSEFPTPLFSGPLEPVACGSVISEGSPLTEQEESSPSHDRSRTVSASSTGDLPKTKTRAADLLVNPLDPRNADKIRVKIADLGNACWVHKHFTEDIQTRQYRSIEVLIGAGYSTPADIWSTACMAFELATGDYLFEPHSGEDYSRDEDHIAHIIELLGSIPRHFALSGKYSREFFNRRGELRHITKLKPWSLFDVLVEKYGWPHEDAAQFTDFLIPMLEMVPEKRASAGECLRHPWLNS
What is the function of this protein?
Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing (PubMed:9446799).  Promotes neuronal apoptosis by up-regulating cyclin-D1 (CCND1) expression (PubMed:19592491).  This is done by the phosphorylation of SRSF2, leading to the suppression of p53/TP53 phosphorylation thereby relieving the repressive effect of p53/TP53 on cyclin-D1 (CCND1) expression (By similarity).  Phosphorylates ACIN1, and redistributes it from the nuclear speckles to the nucleoplasm, resulting in cyclin A1 but not cyclin A2 up-regulation (By similarity).  Plays an essential role in spliceosomal B complex formation via the phosphorylation of DDX23/PRP28 (By similarity).  Probably by phosphorylating DDX23, leads to the suppression of incorrect R-loops formed during transcription; R-loops are composed of a DNA:RNA hybrid and the associated non-template single-stranded DNA (By similarity).
What are the official names of this protein?
SRSF protein kinase 2, SFRS protein kinase 2, Serine/arginine-rich protein-specific kinase 2, SR-protein-specific kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleoplasm. Nucleus speckle. Chromosome. Note=Shuttles between the nucleus and the cytoplasm (By similarity). KAT5/TIP60 inhibits its nuclear translocation (By similarity). Phosphorylation at Thr-492 by PKB/AKT1 promotes nuclear translocation (By similarity). Preferentially localizes across the entire gene coding region (By similarity). During transcription, accumulates at chromatin loci where unscheduled R-loops form and colocalizes with paused 'Ser-5'-phosphorlyated POLR2A/RNA polymerase II and helicase DDX23 (By similarity).
Protein: RS14_SALTI
Sequence: MAKQSMKAREVKRVALADKYFAKRAELKAIISDVNATDEDRWNAVLKLQTLPRDSSPSRQRNRCRQTGRPHAFLRKFGLSRIKVREAAMRGEIPGLKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: RS15_THET2
Sequence: MPITKEEKQKVIQEFARFPGDTGSTEVQVALLTLRINRLSEHLKVHKKDHHSHRGLLMMVGQRRRLLRYLQREDPERYRALIEKLGIRG
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: PYRC_LACPL
Sequence: MTTLIKNAQVWQAGQLQTTDILIAEGRIKAIGHQLHDQFGPADHVICADQHFVSPGFVDVHVHLRDPGQTAKETIATGTLAAAHGGFTTVGAMPNVDPVPDTPERVATMVARNQQEAHVHVAQYASITTGRTSEQLVDFAGIKAAGAFAVSNDGSGVQTAGTMFAAMQGAAKVGLPLAAHVEDDSLYHHGVMNAGPVADRLGLPGINNVSEAAQVARDVMLAEASGVHYHVCHVSTAESLRVIRNAKAAGINVTCEVSPHHLLLCDEDITMDNPMLKMNPPLRSAKDRAALVAGLLDGTIDMIATDHAPHTDAEKQGSMKTAAFGITGIETAFATLYTALVKTRLLTLGRLIELMSTRPAELFGLNTAGRLVVGAPADLTIIDLDHQYEIEAATMLSKGHNSPFIGWPVYGNVLMTLVDGKLAYGKETQA
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: RL27_CAUVC
Sequence: MAHKKSGGSSSNGRDSESKRLGVKKFGGEKVLAGNILVRQRGTKFYPGSGVGIGKDHTLFALVQGAVGFVTKKHNRTYVTVTPAAQPAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: GRP2B_XENLA
Sequence: MDSSDLDKGLTIDEIIAKCIQSFDKDGKLSDPKLVQMFLMMHPWYIPSGDLAKKLFALSESGDNVERERICQFVRFWISEFPAEFDLNPELGEQIRDLKRALENKGNRRESSLIDIESVPSYGWKRQVTQRGPGGGRVRKTSLLFDHLDPAELAEHLTHLEFHSFSKILFQDYHSFVLHGCTVGNPVLERFIALFNGVSQWIQLMVLSKHTPQQRAAVIKQFVQVAERLLQMQNFNTLMSVVGGLSHSSISRLKDTQSHISPETTKVYDSLLELLTSSDNYARYRRRFATCKGFRFPALGVHLKDLMALHVALPDWADKAKTIINISKMRQVYKVVHELTEAQRLEPPVKANPDLLNLLTVSLDQYRSEEEIYQLSLQREPRARSTQTHAKSPPSPSPPLEEWASLKAKPDQALLCQHIEKMVESVFRLFDEDGDGHISQEEFQSVRSNFPYLCAFNEIDQNQDGKISKQEMTSYFLRASSVLDCKMGFIHNFAERTFLRPVSCQHCRNLILGIYKKGLKCKACGITCHKHCRDHLSIECKKRSKSVSERGESMEKGRHFFFTLPRSFRRSTLYPDLREEEPHMEDDGVFDDHL
What is the function of this protein?
Functions as a calcium- and DAG-regulated nucleotide exchange factor specifically activating Rap through the exchange of bound GDP for GTP.  May function in cell aggregation and adhesion.
What are the official names of this protein?
RAS guanyl-releasing protein 2-B.
What is the protein family that this protein belongs to?
Belongs to the RASGRP family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein. Synapse, synaptosome. Note=Found both in the cytosol and associated with membranes.
Protein: MTNA_YEAS7
Sequence: MSLEAIVFDRSEPENVSVKVLDQLLLPYTTKYVPIHTIDDGYSVIKSMQVRGAPAIAIVGSLSVLTEVQLIKHNPTSDVATLYSLVNWESTKTVLNKRLDFLLSSRPTAVNLSNSLVEIKNILKSSSDLKAFDGSLYNYVCELIDEDLANNMKMGDNGAKYLIDVLQKDGFKDEFAVLTICNTGSLATSGYGTALGVIRSLWKDSLAKTDKADSGLDNEKCPRMGHVFPLETRPYNQGSRLTAYELVYDKIPSTLITDSSIAYRIRTSPIPIKAAFVGADRIVRNGDTANKIGTLQLAVICKQFGIKFFVVAPKTTIDNVTETGDDIIVEERNPEEFKVVTGTVINPENGSLILNESGEPITGKVGIAPLEINVWNPAFDITPHELIDGIITEEGVFTKNSSGEFQLESLF
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase, Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL21_STRPD
Sequence: MSTYAIIKTGGKQVKVEVGQAIYVEKIDAEAGAEVTFNEVVLVGGDKTVVGTPVVEGATVVGTVEKQGKQKKVVTFKYKPKKGSHRKQGHRQPYTKVVINAINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: RS19_LACDA
Sequence: MSRSIKKGPFADAHLLKKVDEQQAAEKKQVIKTWSRRSTIFPSFVGLTIAVYDGRKHVPVFVTEDMVGHKLGEFVPTRTFRGHKADDKASK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: CARM1_DROER
Sequence: MSSLRPEEARKLATAASVSPLSNCQFSGVVISSIADEQKLEFTNKYKGSCTLLCSYDSQGVVLRVVSDDDRSHVLKEYMIAADTDAAQMGRRSYAVSLDADNLVLRFASDQDQQLFRKVVENVKHLRPKSVFSQRTEESSASQYFQFYGYLSQQQNMMQDYVRTSTYQRAILGNAVDFQDKIVLDVGAGSGILSFFAVQAGAAKVYAIEASNMAQYAQQLVESNNVQHKISVIPGKIEEIELPEKVDVIISEPMGYMLYNERMLETYLHARKWLKPQGKMYPTHGDLHIAPFSDESLYSEQYNKANFWYQSAFHGVDLTTLHKEGMKEYFRQPIVDTFDIRICMAKSVRHVCDFLNDKEDDLHLISIPLEFHILQTGICHGLAFWFDVEFSGSSQNVWLSTSPTAPLTHWYQVRCLLPMPIFIKQGQTLTGRVLLEANRRQSYDVTIDLHIEGTLISSSNTLDLKNPYFRYTGAPVQAPPGTSTQSPSEQYWTQVDTQGSRNSSSMLNGGLSVNGIGDGMDITHGLMHPH
What is the function of this protein?
Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in proteins.  May methylate histone H3 at 'Arg-17' and activate transcription via chromatin remodeling.
What are the official names of this protein?
Histone-arginine methyltransferase CARMER.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MNMA_LACP7
Sequence: MKKVVVGMSGGVDSSVAAYLLKEAGYDVIGVTMQIWQDEDNQTVEENGGCCGLSAVDDARRVANSLDIPYYVMNFKSEFKANVMDYFVKEYQAGRTPNPCIACNRYVKWESLLTRSLQIGADYIATGHYARIVTLPNGRFALKKSATAAKDQTYALYNLTQDQLSKTLMPVGEYTKEEVREIAAKIGLLVANKPDSQEICFVPDNNYAGFIEDYTGQKIIPGNFVDTKGNILGRHQGIIHYTVGQRKGLGIALGRPAFVVEIRPETNEVVIGSNDDIFTDRLIANKLNAMAVEEFEDGMEVIAKIRYNHEGSKCTIRKVSDTEIACEFETPQRAVTPGQAVVFYQGDIVVGGGTIIK
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_STRP7
Sequence: MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: LEU1_LEIXX
Sequence: MKNTQAPSAMPIHKYRPFHEQIAVDLPDRTWPAKRIAVAPRWCAVDLRDGNQALIDPMSPERKRIMFDLLVRMGYKEIEVGFPSASQTDFDFVRSLIEENAIPDDVTIQVLTQAREHLIKRTYDSLVGAKRAIVHLYNSTSVLQREVVFRSDRQGIVDIALAGARLCRQFEALAPGTEIYYEYSPESYTGTELEFAADICNQALEVFEPTPERKVIINLPATVEMATPNVYADSIEWMSRHLNHRENVILSLHPHNDRGTAVAAAELGYLAGADRIEGCLFGNGERTGNVDLVTLGVNLFTQGIDPQIDFSDIDHIKRTVEHCNQLPVGERSPWGGDLVFTAFSGSHQDAIKKGFEAMAARAQRESVDVDDLVWAVPYLPIDPKDLGRSYEAVIRVNSQSGKGGVAYLLKSDHALDLPRKLQIEFSGVVQAKTDAEGGEVTSNEIWAIFQDEYLPAPETESDAKWGRFELGSTSTANENGDHVTLTVTLRDGETVSKATGEGNGPIAAFFDILNARGINVHLYDYSQHTLSASESATAAAYVEVNVDGRRLWGVGIDADTTTASFKAVISAVNRSVRASASSVPAELAGV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
Protein: CYB_AKOAL
Sequence: MKILRKNHPLLKIVNHSFIDLPTPSSISSWWNFGSLLGVCLMIQILTGLFLAMHYTSDTTTAFSSVAHICRDVNYGWLIRYLHANGASMFFICLFIHVGRGIYYGSYVLSETWNIGIILFLTTMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGSTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVLVHLLFLHETGSNNPSGLNSDSDKIPFHPYYTIKDLLGILLLLLALMILALFFPDILGDPDNFTPANPLNTPAHIKPEWYFLFAYAILRSIPNKLGGVLALILSILILATFPLLNTSKQHGLIFRPITQTIYWTFIANLLVLTWIGGQPVEYPFTTIGQIASITYFTIIIILMPVSNTIENNIIKL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RS16_SHEAM
Sequence: MVTIRLARGGAKKRPFYNIVVTDSRNARDGRFIERVGFFNPLAKGQEETLRLDLDRVDHWVGNGASTTDRVAKLIKDARKAAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: SYI_TREPS
Sequence: MYTPVDPKVDFVAQERRILAFWRERRVFEQSVAQRAQGKSYVFFDGPPFATGLPHFGHFVPSTIKDIIPRYQTMRGAYVPRRFGWDCHGLPIEHLIEQELNLNSKSDVESYGVSAFNAACRSSVLRYVKEWQRTLTRLGRWVDFDNDYKTMDVCYMESVWWVVAQLWQRKLLYEGYKILPYCPRCATALSNHELNLGGYQDVSDPAITVRFECTSVVPGSPAAREFCAAASWGSASLPAHTCFLAWTTTPWTLPCNAALALGPQILYVLIEANDEHYILARSRLEFYYPDSSAYRVVWEKRGEHLAGIRYRPLFSYPVFGQGPDPSVQGDSEEGLFCTRVADFVSTEDGTGVVHVAPAFGEDDYEVFKDAGISIQCPLDAECRFTAEVADYQGLFVKAADKAIIARVQKQGALFRREQISHAYPHCWRCASPLIYRAVHSWFVAVEKIKDKMLAANASICWQPSHIRDGRFGKWLVCARDWAISRDRYWGNPLPIWRCVHCGATDCIGSRTQLYERSGMLLEDLHKHVVDMVTIPCACGSVMRRVPEVLDCWFESGAMPYAQQHYPFEHATDFERYFPAHFISEGLDQTRGWFYTLTILAVALFERPAFENCIVTGLVLASDGKKMSKALRNYADPNEVMDRYGADALRLFLVRSAVVRADDLKYSDEGVKDILKTVIIPLWNSYSFYVTYANIDGIDPPVCAKVDGMGQAVTRLATHLNNPLDRWILSLTEKLVQDIACALDAYDVSKVADPIVSYVDQLNNWYIRRSRRRFWKSINDEDKRCAYNTLYCVLKRCVLAIAPVVPFITESIWQNIRAADDVQSVHLADYPVCTPMVRDDALEFKMETVQRVVSMARAIRAQCNLKVRQPLKAMQVITRNPMERSALLEMEEDVLDELNVKELVFHEKEDEIVEYRAKANFRVLGKELGSKTKRAALSIERLSSAEIQEILEGTTLYLDVDGDRLELTEEKILVQRIERESLKAINEGTLTVALDTTLTEDLLLEGAIRDLVRGVQNLRKERGFSLVDRICLRVFSSDQDIVCARKAYDLHRSYIVGETLAAHVQWARVRDGASAVYVKSDAVLWEVSIDKA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.