PharMolix/UniProtQA huggingface dataset:
Protein: RAD54_CHICK
Sequence: LAKRKAGGEEEDGEWRPPATQKRQKAGSEAESADCYRSPFRKPLTQLTNRPLCLDSSQHEAFIRSILSKPFKVPIPNYKGPTGLRALGIKRAGLRSPLHDPFEEGALVLYEPPLLSAHEQLKIDKDKVPVHVVVDPVLSRVLRPHQREGVKFLWDCVTSRRIPGSHGCIMADEMGLGKTLQCITLMWTLLRQSPDCKPEIEKAMVVSPSSLVRNWYNEVEKWLGGRIQPLAIDGGSKEEIDRKLVGSMNQRGLRVPSPILIISYETFRLHAEALQKGSVGLVICDEGHRLKNSENQTYQALNSLNTPRRVLISGTPIQNDLLEYFSLVHFVNSGILGTAQEFKRHFELPILKGRDADASEAERQKGEERLKELISIVNRCLIRRTSDILSKYLPVKIEQVVCCRLTPLQAELYKNFLKQAKPVEELKEGKINVSSLSSITSLKKLCNHPALIYDKCVEEEEGFMGALDLFPAGYSTKSVEPQLSGKMLVLDYILAVTKSTSNDKVVLVSNYTQTLDLFEKLCRNRRYLYVRLDGTMSIKKRAKVVERFNSPSSPEFIFMLSSKAGGCGLNLIGANRLVMFDPDWNPANDEQAMARVWRDGQKKTCYIYRLLSTGTIEEKIFQRQTHKKALSSCVVDEEQDVERHFSLGELKELFSLNETTISDTHDKIKCRRCVNGHQVRPPPEGSDCTSDLSQWNHCADKRGLQDSVLKAAWDAAVTFTFHHHSHEEQRGIP
What is the function of this protein?
Plays an essential role in homologous recombination (HR) which is a major pathway for repairing DNA double-strand breaks (DSBs), single-stranded DNA (ssDNA) gaps, and stalled or collapsed replication forks.  Acts as a molecular motor during the homology search and guides RAD51 ssDNA along a donor dsDNA thereby changing the homology search from the diffusion-based mechanism to a motor-guided mechanism.  Plays also an essential role in RAD51-mediated synaptic complex formation which consists of three strands encased in a protein filament formed once homology is recognized.  Once DNA strand exchange occured, dissociates RAD51 from nucleoprotein filaments formed on dsDNA.
What are the official names of this protein?
DNA repair and recombination protein RAD54-like, Putative recombination factor GdRad54, RAD54 homolog.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GPAM1_BOVIN
Sequence: MARDLIGPALPPGFKAGGSAEDEERDSSPVAGPALPPNYKSSSSESSDSDEDSSSLSEEGNQESEEDDTGPPARKLRRNQDDDDDDDDEGFFGPALPPGFKKQDDSPPRPMIGPALPPGFLKSTQKSDEGRSDPGQVSSDFNSEKETDSSEEEDIVGPMPAKGPVNSSVTAEFEKRAQRMKEKLTKGDDDSSKPITRESWMTELPPEMKDFGLGPRTFKRRADGKSGDRSVWTDTPADRERKAKVRGLVCSCISVHVGSILKKNRRQNYSRVLFLSL
What are the official names of this protein?
GPALPP motifs-containing protein 1.
Protein: ERA_TROW8
Sequence: MVVSRSPGGYRSGIITLVGRPNVGKSTLINSLVGEHLSITSDKPQTTRRIIRGVISRMNAQIAITDTPGIHKPKTPFGKGLNEMTTCALSASDSIGICLPVNQKIGSGDRFILDKVEAIGPYKKIAIVTKIDRVEKRDLLLKLSEISDLGCNFAAVVPVSAKRAVQIDLLKDVFFENCLNFSEKLFFDHEKPSVSDQISELIREKALCLLEQEIPHSLLVEVEEILTDSNRVFIHANLYVERNSQKMIVLGKGGRTIKNISITSRLAIESFLGKKVYLRLIVKVVKNWQKSESFLGKIYLS
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: HEPT_SHEON
Sequence: MNDIIINKIATIKRCIKRIQQVYGDGSQFKQDFTLQDSVILNLQRCCEACIDIANHINRQQQLGIPQSSRDSFTLLAQNNLITQPLSDNLKKMVGLRNIAVHDYQELNLDIVVHVVQHHLEDFEQFIDVIKAE
What is the function of this protein?
Toxic component of a type VII toxin-antitoxin (TA) system.  A bacteriostatic toxin; upon overexpression in situ or in E. coli inhibits cell growth.  Cells swell slightly.  Neutralized by cognate antitoxin MntA (PubMed:26112399, PubMed:29555683, PubMed:33045733).  Cleaves mRNA in a probably endonucleolytic manner; has no activity on rRNA, tRNA, ssDNA or dsDNA.  The TA system confers plasmid stability in E. coli (PubMed:29555683).  Neutralization is mostly due to tri-AMPylation by MntA (PubMed:33045733).
What are the official names of this protein?
mRNA nuclease HepT, Toxin HepT.
What is the protein family that this protein belongs to?
Belongs to the HepT RNase toxin family.
Protein: RL35_PASMU
Sequence: MPKIKTVRGAAKRFKKTASGGFKRKQSHLRHILTKKTTKRKRHLRHKSMVAKADQVLVVACLPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: UPPP_ECO7I
Sequence: MSDMHSLLIAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDTAKTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGRPLQHEGESKGRLTLIHILLGMIPAVVLGLLFHDTIKSLFNPINVMYALVVGGLLLIAAECLKPKEPRAPGLDDMTYRQAFMIGCFQCLALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATALDLYKSWGFLTNGDIPMFAVGFITAFVVALIAIKTFLQLIKRISFIPFAIYRFIVAAAVYVVFF
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HYCF_ECOLI
Sequence: MFTFIKKVIKTGTATSSYPLEPIAVDKNFRGKPEQNPQQCIGCAACVNACPSNALTVETDLATGELAWEFNLGHCIFCGRCEEVCPTAAIKLSQEYELAVWKKEDFLQQSRFALCNCRVCNRPFAVQKEIDYAIALLKHNGDSRAENHRESFETCPECKRQKCLVPSDRIELTRHMKEAI
What is the function of this protein?
Probable electron transfer protein for hydrogenase 3.
What are the official names of this protein?
Formate hydrogenlyase subunit 6, FHL subunit 6, Hydrogenase-3 component F.
Protein: PRVB1_MERAP
Sequence: AFAGILADADITAALAACKAEGTFTHGEFFTKIGLKGKSAADIKKVFGIIDQDKSDFVEEDELKLFLQNFSAGARALTDAETATFLKAGDSDGDGKIGVDEFAAMVKG
What is the function of this protein?
In muscle, parvalbumin is thought to be involved in relaxation after contraction.  It binds two calcium ions (By similarity).
What are the official names of this protein?
Parvalbumin beta 1.
What is the protein family that this protein belongs to?
Belongs to the parvalbumin family.
Protein: CHEY_HALS3
Sequence: MAKQVLLVDDSEFMRNLLREILEEEFEIADEAENGVEAVEMYKEYDPDLVMMDIVMPIRDGIEATSEIKEFDAGAHIIMCTSIGQEEKMKKAVKAGADGYITKPFQKPSVMDAISDVLTA
What is the function of this protein?
Involved in the transmission of sensory signals from the chemoreceptors and photoreceptors to the flagellar motors.
What are the official names of this protein?
Chemotaxis protein CheY, Response regulator CheY.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FRDC_YERPS
Sequence: MTTKRKAYVRTMAPNWWQQLGFYRFYMLREGTSIPAVWFSVLLIYGVFALKSGPAGWEGFVSFLQNPLVLFLNILTLFAALLHTKTWFELAPKAVNIIVKSEKMGPEPMIKALWVVTVVASAIILAVALL
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit C, Fumarate reductase 15 kDa hydrophobic protein, Quinol-fumarate reductase subunit C, QFR subunit C.
What is the protein family that this protein belongs to?
Belongs to the FrdC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYGA_XYLFA
Sequence: MSDSRGVLSISTSTTFQGLIHTLNRYWAEQGCVLVQPLDLEVGAGTFHPATFLRALGPEPWNAAYVQPSRRPTDGRYGENPNRLQRYYQYQVAMKPNPDNLQELYLASLQALGIDPLVHDVRFVEDNWESPTLGAWGLGWEVWLNGMEVTQFTYFQQAGGLECKPVLGEVTYGLERLCMYLQSCDNVYDLVWTYGPDGTPVTYGDVYHQNEVEQSAYNFEHANVTELLHTFDACEREAKALVEAVLPLPAYEKVIKASHCFNLLDARRTISVTERQRYILRIRTLSQEVAKAYYAQREKLGFPNLRR
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPB_LEPBL
Sequence: MRMIRFRKKIPYLRYLEMQEKLRKFRRECILFLEHAPIITGGINYNPENLLLGKEFLESQGIQVHFVQRGGDFTAHEPGQLVIYPHVDLKKRNLPIRFYLENLLQSVIDSARTTWGLNLITDSDSPGLYLESNSSKKICSIGVNFKSFFTSHGVAFNLNNDFTAFRCINPCGRNWTDMTSVEKLGLDSGFAKRNQFISFMKANLNSFLGPISKLTHTVI
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRF_CANMA
Sequence: MVSTKTYTTRASTHPSPVAQRLFHLMDTKKANLCASVDVQTTSEFLSLIDKLGPYICLVKTHIDIIDDFSYEGTIVPLLELARKHNFMIFEDRKFADIGNTVKHQYTSGVYKISSWSDITNAHGVTGAGVVDGLKQGALETTKEPRGLLMLAELSSKGSLAYGEYTEKTVEIAKLDKEFVIGFIAQRDMGGHDEGFDWIVMTPGVGLDDKGDGLGQQYRTVDEVVSTGTDVIIVGRGLFGKGRDPEVEGKRYRDAGWNAYLKRTGQ
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase, Uridine 5'-monophosphate synthase, UMP synthase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family.
Protein: CENL2_HUMAN
Sequence: MGRVRNRATAQRRRRKRPGDPPAACAAIAVTGASRAQCPRVQVGVGSHAAAKRWLGRWRRKRRWRRVRKAGPRDLLPSAPTPDPPGPAPSPKDLDLGAQRERWETFRKLRGLSCEGAAKVLLDTFEYPGLVHHTGGCHCGAVRFAVWAPADLRVVDCSCRLCRKKQHRHFLVPASRFTLLQGAESIVTYRSNTHPALHSFCSRCGVQSFHAAVSDPRVYGVAPHCLDEGTVRSVVIEEVGGGDPGEEAAEEHKAIHKTSSQSAPACPREQEQ
What are the official names of this protein?
Centromere protein V-like protein 2, Centromere protein V pseudogene 2.
What is the protein family that this protein belongs to?
Belongs to the Gfa family.
Protein: CUZ1_YEAST
Sequence: MSAAIEKETGMLDVGKHCAYCRQLDFLPFHCSFCNEDFCSNHRLKEDHHCRWLLEHEEVHKTEKSPSKSRDGSSSNDEAYFKSLLPERASVRIQRVSETREPLRGSNTAKVSSTLNSKTLDKIFKFFQRNEKRKSNNKSKKNFGSSSNKIIQLANLKKIAKGDPKIPMQNRIYIWCYLVDGDETDIAKEDTRMPLYINKMWPVGRAMDYLSIQLNVKSSTLTNSSSNDKFQLCKLKEGKQVSFYNIGASLRVTNEIKDLDTLYLVHNNADEKSN
What is the function of this protein?
Promotes efficient arsenite-induced clearance of stress granules (SGs) (PubMed:29804830).  May have a role in the ubiquitin-proteasome system (UPS) protecting cells from metalloid-induced proteotoxicity (PubMed:24121501, PubMed:24297164).
What are the official names of this protein?
CDC48-associated ubiquitin-like/zinc finger protein 1, CDC48-associated UBL/Zn-finger protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RR3_CHLVU
Sequence: MGQKVHPIGFRLGITQKHRSYWCTTPQKSALWIQDASFLRNFIKKKYIGAGITHIEIQRQDVDSPSLGIQIYAARLRQIAGNDSKGLERLQEELVKQLQIFYRKRNLVEPGTIHLRLSVKPLRAPEAYAEVLAEKLVEELEQRKPFRRAMRQTVQRALRAGVKGIKVQISGRLNGADIARSEDVREGPVPLQTLRADIDYSSKPAKTIFGLLGIKIWVFRGERLTRISNVR
What are the official names of this protein?
30S ribosomal protein S3, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: BMR1_BACSU
Sequence: MEKKNITLTILLTNLFIAFLGIGLVIPVTPTIMNELHLSGTAVGYMVACFAITQLIVSPIAGRWVDRFGRKIMIVIGLLFFSVSEFLFGIGKTVEMLFISRMLGGISAAFIMPGVTAFIADITTIKTRPKALGYMSAAISTGFIIGPGIGGFLAEVHSRLPFFFAAAFALLAAILSILTLREPERNPENQEIKGQKTGFKRIFAPMYFIAFLIILISSFGLASFESLFALFVDHKFGFTASDIAIMITGGAIVGAITQVVLFDRFTRWFGEIHLIRYSLILSTSLVFLLTTVHSYVAILLVTVTVFVGFDLMRPAVTTYLSKIAGNEQGFAGGMNSMFTSIGNVFGPIIGGMLFDIDVNYPFYFATVTLAIGIALTIAWKAPAHLKAST
What is the function of this protein?
Energy-dependent efflux pump responsible for decreased drug accumulation in multi-drug-resistant cells.  Probably uses a transmembrane proton gradient as the energy source.  Causes the efflux of a variety of toxic substances, including such structurally diverse compounds as ethidium bromide, rhodamine and acridine dyes, tetraphenylphosphonium, puromycin, chloramphenicol, doxorubicin, and fluoroquinolone antibiotics.
What are the official names of this protein?
Multidrug resistance protein 1, Multidrug-efflux transporter 1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RBL_DROCA
Sequence: GVGFKAGVKDYKLTYYTPEYQTLDTDILAAFRVTPQPGVPPEEAGTAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVSGEENQFIVYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEALYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGIDFRVLAKALRMSGGDHIHSGTVVGKLEGERDITLGFVVLLRDDFIEKDRSRGIYFTQPWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNPPGAAANRVALEACVQARNHGQDLAREGNDVIRRASKWSPELSSACEVWKEIKLYFEAMDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SYE2_BARBK
Sequence: MIKVRFAPSPTGYIHIGNTRIALFNWLYAQANNGTFILRYDDTDLERSKQEYIDGIMTDLEWLDIKPDEIHHQSKRFSRYDKVAETLKERGLLYPCYETVEELGRHRKIQLSRKLPPVYDRRALKLTKEDKRLLESQGRKPHWRFLLPNFESNPFQIKRTEISWDDIVKGKQTIDLASISDPVLIREDGSYLYTLPSVIDDIDMAITHIIRGEDHITNTGAQITIFEALNAKLPAFGHINLLTTVSGQGLSKRNSDLSICSLREEGFESMAVRCLSVLTGTSKNIEAHRDQKALLEHFSLQNTSKSAAKFDITDLISLNSHFVHELTYEEVKTRLEKLSICGEKAEYFWNTIRDNIDKVNDAALWWEIIHSDQSFDAVSFEDRAFLQQSVDLLPEGSLNDESWKIWTTALKEKTDRKGKALFMSLRLALTGRQHGPEMGKLLPLLGREKIINRLTI
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 2, Glutamyl-tRNA synthetase 2, GluRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_MAGMM
Sequence: MENFRYEIESMLQLVGVDMDVISVDPYSDEKLAEFVSELLLWNKKINLIGKSTEKSIWSRHIAESLILLPYVQGSTVLDMGTGAGLPGLPLQIVSGSNIEMHLVEKDQKKVSFLKHVSANLNLKNIRIYNKQFTEKGFDGAPLVNVVTSRALAEINQLVAWADPCLVNGGSLVLIKGPVCKAELEKFEESDLSDKYENGEIVEYKIDSHDVNIVIIKKK
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GL_HHV2H
Sequence: MGFVCLFGLVVMGAWGAWGGSQATEYVLRSVIAKEVGDILRVPCMRTPADDVSWRYEAPSVIDYARIDGIFLRYHCPGLDTFLWDRHAQRAYLVNPFLFAAGFLEDLSHSVFPADTQETTTRRALYKEIRDALGSRKQAVSHAPVRAGCVNFDYSRTRRCVGRRDLRPANTTSTWEPPVSSDDEASSQSKPLATQPPVLALSNAPPRRVSPTRGRRRHTRLRRN
What is the function of this protein?
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell.  Acts as a functional inhibitor of gH and maintains gH in an inhibited form.  Upon binding to host integrins, gL dissociates from gH leading to activation of the viral fusion glycoproteins gB and gH.
What are the official names of this protein?
Envelope glycoprotein L, gL.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein L family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Extracellular side. Host cell membrane; Peripheral membrane protein; Extracellular side. Host Golgi apparatus, host trans- Golgi network. Note=gL associates with the extravirion surface through its binding to gH. During virion morphogenesis, this protein probably accumulates in the host trans- Golgi where secondary envelopment occurs.
Protein: RS16_PHYAS
Sequence: MAIKMRLQRFGVHKRPFYRVVASDSRVTRDGKFLDIVGTYDTILNIIKLDNEKVQKWLSCGAQPTQTVKKILKKNFVFQKDNQIKKPQTAK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: NOTO_MOUSE
Sequence: MSSPAPSGTQVQPGSLRPCPGAVSPVVPRRLARGRLESSFSVEAILARPKTRELAATSLPLSTCTSLNLLGAVSQYGVLPWVCSTGSWLPAYLSVGVYPLCSMSCVPGLNVTHHQQGLRLTGSELPYCLGPLKWAPTVDLRDHGTERHTKRVRTTFNLQQLQELEKVFAKQHNLVGKERAQLAARLHLTENQVRIWFQNRRVKYQKQQKLKLPSSSVMEEPSSSSDGNIQSEDAELGIGS
What is the function of this protein?
Transcription factor that controls node morphogenesis (PubMed:15231714, PubMed:17884984, PubMed:18061569, PubMed:22357932).  Acts downstream of both FOXA2 and Brachyury (T) during notochord development (PubMed:15231714).  Is essential for cilia formation in the posterior notochord (PNC) and for left-right patterning; acts upstream of FOXJ1 and RFX3 in this process and is required for the expression of various components important for axonemal assembly and function (PubMed:17884984).  Plays a role in regulating axial versus paraxial cell fate (PubMed:18061569).  Activates the transcription of ciliary proteins C11orf97 homolog, FAM183B and SPACA9 in the embryonic ventral node (PubMed:27914912).
What are the official names of this protein?
Homeobox protein notochord.
What are the subcellular locations of this protein?
Nucleus.
Protein: CHS1_TRISU
Sequence: MVSVAEIRKAQRAEGPATILAIGTANPPNRVEQATYPDFYFKITNSEHKVELKEKFQRMCDKSMIKSRYMYLTEEILKENPSVCEYMAPSLDARQDMVVVEVPRLGKEAAVKAIKEWGQPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRPYVKRYMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEVTAVTFRGPSDTHLDSLVGQALFGDGAAALIVGSDPVPEIEKPIFEMVWTAQTIAPDSEGAIDGHLREAGLTFHLLKDVPGIVSKNIDKALVEAFQPLNISDYNSIFWIAHPGGPAILDQVEQKLSLKPEKMKATRDVLSEYGNMSSACVLFILDEMRKKSAQDGLKTTGEGLEWGVLFGFGPGLTIETVVLHSVAI
What is the function of this protein?
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
What are the official names of this protein?
Chalcone synthase 1, Naringenin-chalcone synthase 1.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: Y2526_ANOFW
Sequence: MSTGSAHVQMVIITGMSGAGKTVAIQSFEDLGYFCVDNLPPTLLPKFLELIRESGNKMNKIALVMDLRSRDFFDRLFVALDDLAETSWVTPKILFLDANDATLVSRYKETRRSHPLAPSGLPLEGINLERQLLEELKGRAQMIIDTSNLKPRELREKIVQTFATPTTTTFSVNVVSFGFKYGLPIDADLVFDVRFLPNPHYIEHMRPKTGLDEEVSSYVLKWTETQKFIEKVTDLLSFMLPHYKREGKSQVVIAIGCTGGQHRSVTLAEYIGRYFADEYTTHVSHRDIAKRKDTHR
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Aflv_2526.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: CBIX_SULIM
Sequence: MLGVLLVLHGSKIPEWKDVGIKYAEYLSRYFNLVEFGFLEFNKPTLSEALSNLLAKGANKIVVVPLLFATGTHFKRDIPRLLGIDGDEKKIQYMGKEIEIIIADPLGFDEKIGEVLVKRVNETYNKNY
What is the function of this protein?
Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis.
What are the official names of this protein?
Sirohydrochlorin cobaltochelatase, CbiXS.
What is the protein family that this protein belongs to?
Belongs to the CbiX family. CbiXS subfamily.
Protein: RNC_PSEFS
Sequence: MTVSLARLERQLGYTFKDQELMVLALTHRSFAGRNNERLEFLGDAILNFVAGEALFERFPQAREGQLSRLRARLVKGETLAVLARGFGLGEYLRLGSGELKSGGFRRESILADALEALIGAIYLDAGMEAAKERVTAWLTSEIESLTLVDTNKDPKTRLQEFLQSRGCELPRYEVVDIQGEPHCRVFFVECEITLLNEKSRGQGVSRRIAEQVAAAAALIALGVENGHD
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T132B_HUMAN
Sequence: MFGAASRMDTTAVCTGGVTESRGIVDSLQKFSSLPAYLPTNLHISNAEESFFLKEANQDLTRNSSLQARVEPFFIYRARTPPIINASYGPFSVEKIIPQELLLTSTAFGNMDKFPFNWKLKSHILDSSIYSNRPKVQTLFYVTGMGWDDSDLTEDLPCVKMFAFPEAREVAASCRLQGAPGLCVAELELLPEWFSSGLDLEPEEEIPALLGGTTMELFFTLYPADKAGQCPLEEEGKWENNIHSGLESPQQAFPARERIGSVVVYPTQDDLKWSLVSLDENVVISVPLNLVREGDTATFLVSLTSSSVADQFTLRIKAAAGVKITAVRVSSEDQWAVQEEIDNGSTQTSATLTCMGHRPDTQSRVNGSFYEILQVDFGIDNSSDLAGAQQITWQVEYPIEDSMSELVVSEIFVSQTTFVGIVPLAMDTEVLNTAILTGKPVSVPVKVVGVQEDGSVVDVSESVECKSADEDVIKVSNNCDSIFVNGKEMKSKVDTIVNFTHQHFTSQFEVTVWAPRLPLQIEISDTELSQIKGWRIPVAANRRPTRESDDEDDEEKKGRGCSLQYQHATVRVLTQFVAESPDLGQLTYMLGPDWQFDITDLVTEFMKVEEPKIAQLQDGRTLAGREPGITTVQVLSPLSDSILAEKTVIVLDDRVTIAELGVQLVAGMSLSLQPHRADKRAIVSTAAALDVLQSPQQEAIVSSWILFSDGSVTPLDIYDPKDYSVTVSSLDEMVVSVQANLESKWPIVVAEGEGQGPLIKLEMMISEPCQKTKRKSVLAVGKGNVKVKFEPSSDEHQGGSNDIEGINREYKDHLSNSIEREGNQERAVQEWFHRGTPVGQEESTNKSTTPQSPMEGKNKLLKSGGPDAFTSFPTQGKSPDPNNPSDLTVTSRGLTDLEIGMYALLCVFCLAILVFLINCVAFAWKYRHKRFAVSEQGNIPHSHDWVWLGNEVELLENPVDITLPSEECTTMIDRGLQFEERNFLLNGSSQKTFHSQLLRPSDYVYEKEIKNEPMNSSGPKRKRVKFTSYTTILPEDGGPYTNSILFDSDDNIKWVCQDMGLGDSQDFRDYMESLQDQM
What are the official names of this protein?
Transmembrane protein 132B.
What is the protein family that this protein belongs to?
Belongs to the TMEM132 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RGL3_HUMAN
Sequence: MERTAGKELALAPLQDWGEETEDGAVYSVSLRRQRSQRRSPAEGPGGSQAPSPIANTFLHYRTSKVRVLRAARLERLVGELVFGDREQDPSFMPAFLATYRTFVPTACLLGFLLPPMPPPPPPGVEIKKTAVQDLSFNKNLRAVVSVLGSWLQDHPQDFRDPPAHSDLGSVRTFLGWAAPGSAEAQKAEKLLEDFLEEAEREQEEEPPQVWTGPPRVAQTSDPDSSEACAEEEEGLMPQGPQLLDFSVDEVAEQLTLIDLELFSKVRLYECLGSVWSQRDRPGAAGASPTVRATVAQFNTVTGCVLGSVLGAPGLAAPQRAQRLEKWIRIAQRCRELRNFSSLRAILSALQSNPIYRLKRSWGAVSREPLSTFRKLSQIFSDENNHLSSREILFQEEATEGSQEEDNTPGSLPSKPPPGPVPYLGTFLTDLVMLDTALPDMLEGDLINFEKRRKEWEILARIQQLQRRCQSYTLSPHPPILAALHAQNQLTEEQSYRLSRVIEPPAASCPSSPRIRRRISLTKRLSAKLAREKSSSPSGSPGDPSSPTSSVSPGSPPSSPRSRDAPAGSPPASPGPQGPSTKLPLSLDLPSPRPFALPLGSPRIPLPAQQSSEARVIRVSIDNDHGNLYRSILLTSQDKAPSVVRRALQKHNVPQPWACDYQLFQVLPGDRVLLIPDNANVFYAMSPVAPRDFMLRRKEGTRNTLSVSPS
What is the function of this protein?
Guanine nucleotide exchange factor (GEF) for Ral-A.  Potential effector of GTPase HRas and Ras-related protein M-Ras.  Negatively regulates Elk-1-dependent gene induction downstream of HRas and MEKK1 (By similarity).
What are the official names of this protein?
Ral guanine nucleotide dissociation stimulator-like 3, RalGDS-like 3.