PharMolix/UniProtQA huggingface dataset:
Protein: DPS_STRMG
Sequence: MTNTITENIYASIIHQVEKKENSGNEKTKAVLNQAVADLSKAASIVHQVHWYMRGSGFLYLHPKMDELMDALNGHLDEISERLITIGGAPFSTLKEFDENSRLEETVGTWDKSITDHLKRLVQVYDYLSSLYQVGLDVTDEEDDAVSNDIFTAAQTEAQKTIWMLQAELGQAPGL
What is the function of this protein?
Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral (By similarity).  It binds and incorporates Fe(2+) ion.  Effectively inhibits hydroxyl radical formation by the Fenton reaction and is essential for colony formation in the presence of air.  Is also able to bind zinc ion.  Does not bind DNA.
What are the official names of this protein?
DNA protection during starvation protein.
What is the protein family that this protein belongs to?
Belongs to the Dps family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RN2A_RANLT
Sequence: GLMDALKGAAKNLFASALDKLKCKVTGC
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Ranatuerin-2LTa.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Ranatuerin subfamily.
Protein: GSA_TOLAT
Sequence: MAYSTQRSEQLFTAAQQSIPGGVNSPVRAFNGVGGTPRFIAKADGAYLFDVDGNRYIDYVGSWGPMLLGHNHPAIKAAVLAAVENGLSYGAPTESEVLMAEMIRQIMPDMEMVRMVNSGTEATMSAIRLARGYTGRDKIVKFEGCYHGHADCLLVKAGSGALTLGQPNSPGVPADFAKHTLTCTYNDLASVEATFASYGSEIACIIVEPVAGNMNCIPPVPGFLEGLRAICDKYGALLIIDEVMTGFRVSLQGAQGYYGITPDLTTLGKIIGGGMPVGAFGGKKEIMAYIAPTGPVYQAGTLSGNPVAMAAGLAMLKAIQQPGLYDTLAEKTRQVAEGLKAAAAKQGIPLTVNYVGAMFGFFFTDEPEITRFEQVSRCDIDAFRRFYHLMLQEGVYLAPSAYEAGFLSLAHSEADIAETLAAAERCFAQMK
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPCKG_METM7
Sequence: MYLLTDEVARELKKPFGKVYKELPSIDGKVVSIGDVTTKHLLSNGIIPNLSILDFKTKRNIPVNIPHKFKTIFEVENPQGCISDEAIERIKYLSTIHDRDMALIIKGEEDLLTIPVIKYFPEDTSVIYGQPDEGMVLLKITDELKQKIEKLLKDMEER
What is the function of this protein?
Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
What are the official names of this protein?
GTP-dependent dephospho-CoA kinase, Dephospho-coenzyme A kinase, DPCK.
What is the protein family that this protein belongs to?
Belongs to the GTP-dependent DPCK family.
Protein: DNAK_STAA1
Sequence: MSKIIGIDLGTTNSCVTVLEGDEPKVIQNPEGSRTTPSVVAFKNGETQVGEVAKRQAITNPNTVQSIKRHMGTDYKVDIEGKSYTPQEISAMILQNLKNTAESYLGEKVDKAVITVPAYFNDAERQATKDAGKIAGLEVERIINEPTAAALAYGLDKTDKDEKVLVFDLGGGTFDVSILELGDGVFEVLSTAGDNKLGGDDFDQVIIDYLVAEFKKENGVDLSQDKMALQRLKDAAEKAKKDLSGVSQTQISLPFISAGENGPLHLEVNLTRSKFEELSDSLIRRTMEPTRQAMKDAGLTNSDIDEVILVGGSTRIPAVQEAVKKEIGKEPNKGVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIEILGGRMNTLIERNTTIPTSKSQIYSTAVDNQPSVDVHVLQGERPMAADNKTLGRFQLTDIPPAERGKPQIEVTFDIDKNGIVNVTAKDLGTNKEQRITIQSSSSLSDEEIDRMVKDAEVNAEADKKRREEVDLRNEADSLVFQVEKTLTDLGENIGEEDKKSAEEKKDALKTALEGQDIEDIKSKKEELEKVIQELSAKVYEQAAQQQQQAQGANAGQNNDSTVEDAEFKEVKDDDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: BMH1_YEAST
Sequence: MSTSREDSVYLAKLAEQAERYEEMVENMKTVASSGQELSVEERNLLSVAYKNVIGARRASWRIVSSIEQKEESKEKSEHQVELICSYRSKIETELTKISDDILSVLDSHLIPSATTGESKVFYYKMKGDYHRYLAEFSSGDAREKATNASLEAYKTASEIATTELPPTHPIRLGLALNFSVFYYEIQNSPDKACHLAKQAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMSESGQAEDQQQQQQHQQQQPPAAAEGEAPK
What is the function of this protein?
Involved in growth regulation.
What are the official names of this protein?
Protein BMH1.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
Protein: Y566_MYCPN
Sequence: MRKQFLIAHRGYSTIAPENTHLAFAAAQLFGFDGLWMEVQLTKDKQIVVTNLDNYKVGNKTHKLSDINLVNLKKINLAKQFKVNVQEQTILTLKEVLMEFLTPFRFLLLFIKGEEEQQNQVLVEQLAQLLEGFELAKEKLILLSSHFSTIKYLNEKLKSFKTSFVFNSKKQLVHLTKDEITQNCRFLAPNDSFYHKNCAELQSYGLPIILWVIKGLLRYQFYENDRFVKFQIAAQLY
What are the official names of this protein?
Uncharacterized protein MG385 homolog.
What is the protein family that this protein belongs to?
To M.genitalium MG293.
Protein: HS90A_CHICK
Sequence: MPEAVQTQDQPMEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKDLKINLIPNKHDRTLTIVDTGIGMTKADLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGSYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRLDNGEPLGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPIRLFVEKERDKEVSDDEAEEKEEEKEEKEEKTEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDEEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFMRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHVYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKAKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDTAAEEASPAVTEEMPPLEGDDDTSRMEEVD
What is the function of this protein?
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction.  Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity.  This cycle probably induces conformational changes in the client proteins, thereby causing their activation.  Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.  Engages with a range of client protein classes via its interaction with various co-chaperone proteins or complexes, that act as adapters, simultaneously able to interact with the specific client and the central chaperone itself.  Recruitment of ATP and co-chaperone followed by client protein forms a functional chaperone.  After the completion of the chaperoning process, properly folded client protein and co-chaperone leave HSP90 in an ADP-bound partially open conformation and finally, ADP is released from Hsp90 which acquires an open conformation for the next cycle.
What are the official names of this protein?
Heat shock protein HSP 90-alpha.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm. Melanosome.
Protein: COBT_VARPS
Sequence: MTDSNQTIPSISDIHDGALAARLQSALDNKTKPLGALGRLESLALRIGLVLGSETPVLEAPQMLVCAADHGLAARGVSAFPSDVTWQMVENFLAGGAAVSVLALQHGLALTVVDCGVRRDFQARPGLVSRRIAAGTADASAGPAMTAEQCAQAIANGREVVRALPGNALLLGEMGIGNSSAAALLLARLAGLDIDGCTGSGTGLDAAGLARKREVLRDVLALHAAASEPLDALAAFGGFEIATLVGAVLQAAQERRVIVIDGFIASAAVLVAQALQPHVAQRCVAAHSSAEPGHALLLKHLGLEPLLNLDLRLGEGSGGALAWPLLESACRILREMASFEAAGVSRKDS
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: GPDA_NEIG1
Sequence: MKITVIGAGSWGTALALHFSQHGNRVSLWTRNADQVRQMQEARENKRGLPGFSFPETLEVCADLAEALKDSGLVLIVTSVAGLRSSAELLKQYGAGHLPVLAACKGFEQDTGLLTFQVLKEVLPDNKKIGVLSGPSFAQELAKQLPCAVVLASENQEWIEELVPQLNTTVMRLYGSTDVIGVAVGGSVKNVMAIATGLSDGLEYGLNARAALVTRGLAEITRLASAMGAQPKTMMGLAGIGDLILTCTGALSRNRRVGLGLAEGKELHQVLVEIGHVSEGVSTIEEVFNTACKYQIDMPITQTLLQLIRKEMTPQQVVERLMERSARFE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU_STRSV
Sequence: MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSAVNQPKDYASIDAAPEERERGITINTAHVEYETAKRHYAHIDAPGHADYVKNMITGAAQMDGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDLLSEYDFPGDDLPVIQGSALKALEGDSKYEDIIMELMDTVDEYIPEPERDTDKPLLLPVEDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEEIQKAVVTGVEMFRKQLDEGLAGDNVGVLLRGIQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQFYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGMVTEIEA
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG166_VACCW
Sequence: MSRVRISLIYLCTFMIITSTKTIEYTACNNTIIIPCTIDNPTKYIRWKLDNHDILTYNKTSKTTILSKWHTSARLHSLSDSDVSLIIEYKDILPGTYTCEDNTGIKSTVKLVQRHTNWFNDYQTMLMFIFTGITLFLLFLEITYTSISVVFSTNLGILQVFGCVIAMIELCGAFLFYPSMFTLRHIIGLLMMTLPSIFLIITKVFSFWLLCKLSCAVHLIIYYQLAGYILTVLGLGLSLKECVDGTLLLSGLGTIMVSEHFSLLFLVCFPSTQRDYY
What is the function of this protein?
Promotes, when overexpressed, the influx of extracellular Ca(2+), leading to membrane permeability and host cell necrosis.
What are the official names of this protein?
Protein OPG166.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG166 protein family.
Protein: SYV_BIFLD
Sequence: MTEGKSIINANLTPLPDKVGVDGLEDKWRAVWDEDGTYKFRNTRDRKAVYSIDTPPPTVSGSLHVGHVFSYTHTDVIARYKRMRGYDVFYPMGWDDNGLPTERRVQNYYGVRVDVSLPYDPDFKPPFEGTDGKKIDAKDQVPISRKNFIELCERLTAQDEKLFEALWRKLGLSIDWSQTYHTIGQHPQRVAQKAFLRNLARGEAYQQDAPGLWDVTFQTAVAQAELESREYPGFYHKVAFRFEDGTPIYIETTRPELLAACTSLIANPNDERYKQYFGQYVYSPLFKVKVPILAHPAAEMDKGAGIAMCCTFGDVTDVEWWRDLKLPTRPIIQRNGRIVMDTPDWIEDPAGREVFAETAGKTTFSARKIIVDKLRESGDLDGEPTPTKRMTNFYEKGDKPLEIVTSRQWYLKNGGTDAKLNAELIERGKELEFHPDFMRVRYENWVHGLNGDWLISRQRFFGVPFPLWYPVNASGEPDYDHPITPSEDRLPIDPTIDVPEGYDESQRDVPGGFTAEKDIMDTWATSSLTPQIVTHWAEPDEASKALFASTFPMDLRPQGQDIIRTWLFSTVDRAHLENKCLPWAHATLSGWILDPDHKKMSKSKGNVVVPNEPIEKFGADAVRYWAAAARLGLDATYDIGQMKIGRRLAIKLLNATKFALAIGREDENHHVGAAAEAAWNPADVTEPLDRAAMAKLALVVRQATEALESYEHSKALEVIESYFWQFCDDYIELVKNRAYGTPDEHGNVPSEKAVKSARTALGLGLDAFARLLAPYLPYATEEVWSWMHAGSGSVHRTAWPVVDPYVEAATGASPELLTWAGKAVEQLRKIKSEAKVSMKTPILSVALSAASEGVEAIHAALGDIAQAGRVVGKFDLVAKHAEESAAEDAPETEVAVEASELGEPPAKKPKH
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IDI_ECOL5
Sequence: MQTEHVILLNAQGVPTGTLEKYAAHTADTLLHLAFSSWLFNAKGQLLVTRRALSKKAWPGMWTNSVCGHPQLGESNEEAVIRRCRYELGVEITPPESIYPDFRYRATDPNGIVENEVCPVFAARTTSALQINDDEVMDYQWCDLAAVLRGIDATPWAFSPWMVMQATNREARKRLSAFTQLK
What is the function of this protein?
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate Delta-isomerase, IPP isomerase, IPP:DMAPP isomerase, Isopentenyl pyrophosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y341_STAAM
Sequence: MASLKNKHFMIGLSLTFIVALFSFLAAKLPILDKVGALTIAILIAILYRHFRGYPEQYSSGITFSSKYLLRFAIILYGLKLNIFDIIGQGSKLLAIDVGVVIFSIVMMLFVNKLLHGDKNIALLLGVGTGVCGAAAIAAVAPIFKSREKDTAISIGIIALIGTIFSLIYTAIYAIFSMTTNVYGAWSGVSLHEIAHVVLAGGFGGSDALKIALLGKLGRVFLLIPLTIVLILIMRFRSSESSSKGRISIPYFLIGFVIMALVNTYVTIPSVLLNILNTISTICLLMAMVALGLNVAFKDLKNRALKPLMTIIITSICLSSLAFIVVHWLYS
What are the official names of this protein?
UPF0324 membrane protein SAV0341.
What is the protein family that this protein belongs to?
Belongs to the UPF0324 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MOG_BOVIN
Sequence: MASLLSSSLPSCLPSLLFLLLQLTSSSAGQFRVIGPGHPIRALVGDEVELPCRISPGKNATGMEVGWYRPPFSRVVHLYRNGKDQDEEQAPEYRGRTQLLKETIGEGKVTLRIRNVRFSDEGGFTCFFRDHSYQEEAAMELKVEDPFYWINPGVLVLIAVLPVLLLQITVGLVFLCLQRRLRGKLWAEIENLHRTFDPHFLMVPCWKITLFVIVPVLGPLVALIICYNWLHRRLAGQFLEELRNPF
What is the function of this protein?
Mediates homophilic cell-cell adhesion (By similarity).  Minor component of the myelin sheath.  May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication.
What are the official names of this protein?
Myelin-oligodendrocyte glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. BTN/MOG family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL16_FRATN
Sequence: MLQPKRTKFRKQQKLRNRGLAHRGNKVSFGEFGLQATSRGRITARQIEAGRRAISRHIKRGGKIWIRIFPDKPITQKPLEVRMGKGKGSVEYWVAQIQPGRVLYEITGVKEELAREAFARAAAKMPVQTTFVEKQVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: RSMH_PSEFS
Sequence: MTIDSGFNHITVLLDEAVEALAVRADGCYLDGTFGRGGHSRLILSQLGSDGKLLGFDKDPQAIATGQALAAEDGRFVVVQRSFAELGAEVAERGMAGKVAGVLLDLGVSSPQLDDPERGFSFMNDGPLDMRMDPTRGVSAAQFIATAPVEEIARVFKEYGEERFAGRMARAVVERREIQPFERTADLAEVLKVANPAWEKGKNPATRAFQGLRIHVNNELGDLEAGLEAALEALEVGGRLVVISFHSLEDRIVKLFMRRLVKGESDNLPRNLPVRFEAFVPKIKIHGKAQFASEAELKANPRSRSAVMRVAEKLR
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECTC_BORPA
Sequence: MIVRNVKDVMGTEDEVRTDTWVSRRVLLKKDGMGFSFHETTIFPGTRTHIHYKNHLEAVWCIEGDGSIETIADGKTYELGPGVVYALNENDEHWLCGGKQPLRVICVFNPPLTGQEVHDAEGVYALVEEAA
What is the function of this protein?
Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.
What are the official names of this protein?
L-ectoine synthase, N-acetyldiaminobutyrate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the ectoine synthase family.
Protein: PA1_POLPI
Sequence: MNFKYSILFICFGTLDRGLIPECPFNEYDILFFVYTRQQRDGIVLTEETLQNYDLFKKSTISRQVVFIDHGFLSNGNNENFIAMAKALIEKDNFLVISVDWKKGACNAFASTLDYLGYSTAVGNTRHVGKYVADFTKLLVEQYKVSMSNIRLIGHSLGAHTSGFAGKEVQELKLNKYSNIDGLDPAGPSFDSNDCPERLCETDAEYVQIIHTSNILGVYSKIGTVDFYMNYGSHQPGCGRFFSPSCSHTKAVKYLTECIKHECCLIGTPWKKYFSTPKPISQCTKDTCVCVGLNAKSYPARGSFYVPVEATAPYCHNEGIKL
What is the function of this protein?
Catalyzes the hydrolysis of phosphatidylcholine with phospholipase A1 activity (PubMed:17761205).  Shows hemolytic activity (PubMed:17761205).  Acts as an allergen (PubMed:17761205).
What are the official names of this protein?
Phospholipase A1, PLA1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: DCD_PSESM
Sequence: MSIKSDKWIRRMAQEHGMIEPFVERQVRGEGANRVISFGVSSYGYDVRCADEFKVFTNINSATVDPKNFDEKSFVDIKSDVCIIPPNSFALARTVEYFRIPRNVLTICLGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTTLPAKIYANEGVAQMLFLESDEECEVSYKDRGGKYQGQRGVTLPRT
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: BIRC5_PIG
Sequence: MSAPSLPPAWQLYLKDHRISTFKNWPFLEGCACTPERMAAAGFIHCPTENEPDLAQCFFCFKELEGWEPDDDPIEEHKKHSSGCAFLSVKKQFEELTLSEFLKLDKERAKNKIAKETNNKQKEFEETAKKVRCAIEQLAASE
What is the function of this protein?
Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity).  Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity).  Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with polymerized microtubules (By similarity).  Involved in the recruitment of CPC to centromeres during early mitosis via association with histone H3 phosphorylated at 'Thr-3' (H3pT3) during mitosis (By similarity).  The complex with RAN plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules (By similarity).  May counteract a default induction of apoptosis in G2/M phase (By similarity).  The acetylated form represses STAT3 transactivation of target gene promoters (By similarity).  May play a role in neoplasia.  Inhibitor of CASP3 and CASP7 (By similarity).  Essential for the maintenance of mitochondrial integrity and function (By similarity).
What are the official names of this protein?
Baculoviral IAP repeat-containing protein 5, Apoptosis inhibitor survivin.
What is the protein family that this protein belongs to?
Belongs to the IAP family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Chromosome. Chromosome, centromere. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Midbody. Note=Localizes at the centromeres from prophase to metaphase, at the spindle midzone during anaphase and a the midbody during telophase and cytokinesis. Accumulates in the nucleus upon treatment with leptomycin B (LMB), a XPO1/CRM1 nuclear export inhibitor (By similarity). Localizes on chromosome arms and inner centromeres from prophase through metaphase. Localizes to kinetochores in metaphase, distributes to the midzone microtubules in anaphase and at telophase, localizes exclusively to the midbody. Colocalizes with AURKB at mitotic chromosomes. Acetylation at Lys-129 directs its localization to the nucleus by enhancing homodimerization and thereby inhibiting XPO1/CRM1- mediated nuclear export (By similarity).
Protein: PYRB_LEGPH
Sequence: MKHFLEISQLSSEQIESLLQRALYFKHTKQYPSYSQSIIANLFYENSTRTRISFELAERHLAMSVVNLDLQTSSETKGEAIEDTIRTLAAMGIQYFVIRHKQDGLQQNLANKLGDTVNIINAGDGTHAHPSQAILDMVTIIEQKKRLDKLKIAILGNIKHSRVANSFQCICSKLGVGELVLISPEIWQPSQVHFGRVTDNLNEGLEGADVVICLRVQKERLLQDDHLDLDFYRNNFALTQKSLSYAKPDAMVMHPGPMNRGVEIDSEVADGNQSCILQQVTNGVYARMAILESLIAS
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: FLA_VIBAL
Sequence: AVNVNTNVSAMTAQRYLNQA
What is the function of this protein?
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
What are the official names of this protein?
Flagellin, Protein 38Va, Omp38Va.
What is the protein family that this protein belongs to?
Belongs to the bacterial flagellin family.
What are the subcellular locations of this protein?
Secreted. Bacterial flagellum.
Protein: RLMC_ECOBW
Sequence: MQCALYDAGRCRSCQWIMQPIPEQLSAKTADLKNLLADFPVEEWCAPVSGPEQGFRNKAKMVVSGSVEKPLLGMLHRDGTPEDLCDCPLYPASFAPVFAALKPFIARAGLTPYNVARKRGELKYILLTESQSDGGMMLRFVLRSDTKLAQLRKALPWLHEQLPQLKVITVNIQPVHMAIMEGETEIYLTEQQALAERFNDVPLWIRPQSFFQTNPAVASQLYATARDWVRQLPVKHMWDLFCGVGGFGLHCATPDMQLTGIEIASEAIACAKQSAAELGLTRLQFQALDSTQFATAQGDVPELVLVNPPRRGIGKPLCDYLSTMAPRFIIYSSCNAQTMAKDIRELPGFRIERVQLFDMFPHTAHYEVLTLLVKQ
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC, 23S rRNA(m5U747)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.
Protein: PDXA_XANCP
Sequence: MVPSLALVPGEPAGIGPELCIRLAQQPRSDAHLIAYADPDTLHSAAKALCLSVRLLDPDQHARLPGDLPLHPVRQAAPTRFGTPDPANAAAVIAGLLGAAGDCLSGKLQGIVTGPVHKAVINAGGIAYTGTTELLAAQAGCPVVMMLANSIVRVALVTTHLPLRAVPEAITAEALARCLRITATAMQRDFGLEHPRIAVLGLNPHAGEDGLLGREELDVIIPVLDQLRSEGMQLIGPLPADTAFLPQKLTDFDAVVAMYHDQGLPVLKYSGFEQAVNITLGLPYPRVAVDHGTALELAGRGVADPSSLLAATALCARLAARS
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_FRATH
Sequence: MPKLKTKSGAAKRFKKTGKGGFKHRCANRAHINTKMTTKRKRHLRGMNQVAKVDTTSLVQQMPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: RECO_NEIMF
Sequence: MSEHRVNHEPVFLLASSPWRESSLRVEAFSRRYGRVALLARSARKRQSELRGVLVPFVPVSASWYGSQELKTLHRAEWIGGWPQPQGRALFSGLYVNELMLKLTVREDPLPELYDALAEVMEAVCCKAAYIDDLRRFEWRLLNLLGVAPDLHADGTGGDILADKTYRLMPEEAVMPVCEDADALSHEAGAIVEGQSLIDLREGSFRTAESLQQALKITRLFIRHLLPEGLKSRQVLEQIRQFDRKETARETVPTSDGTASNAV
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: ORR4_ORYSI
Sequence: MTVVDAESRFHVLAVDDSLIDRKLIEMLLKNSSYQVTTVDSGSKALELLGLRDEGDDSSSSPSSSSPDHQEIDVNLIITDYCMPGMTGYDLLKRVKGSSSLKDIPVVIMSSENVPARINRCLEDGAEEFFLKPVKLADMKKLKSHLLKRKQQLPMAAAAPDKPPHKPDEAAASAAAIAEAATAQTDGIISDCSCSGSSKRKAAAMEQEVISSPDQRTKPRLSSTSSGLAVET
What is the function of this protein?
Functions as response regulator involved in His-to-Asp phosphorelay signal transduction system.  Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes.  Type-A response regulators seem to act as negative regulators of the cytokinin signaling.
What are the official names of this protein?
Two-component response regulator ORR4, Type A response regulator 4, OsRR4.
What is the protein family that this protein belongs to?
Belongs to the ARR family. Type-A subfamily.