PharMolix/UniProtQA huggingface dataset:
Protein: MIAA_MYCSS
Sequence: MRPLAIIGPTGTGKSALALDVAERLGGEIGVEIVNADAMQLYRGMDIGTAKLPAAQRRGVPHHQLDVLDVTETASVARYQSEAARDIEAIAARGAVPIIVGGSMMYVQALLDDWAFPATDPAVRARWEQRLAEVGVAALHGELGKVDPDAAASILPTDGRRIVRALEVVELTGQPFAASAPTIGAPRWDTAIIGLDWETTVLDERLAARTDSMFAEGLVAEVAGLLRHGLREGVTASRALGYAQVLADLDAGGDGSAAREPTFVGTRRYVRRQRSWFRRDHRVCWLDGGSPDNVDRTLRAWRAVS
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: MK08_DANRE
Sequence: MNRNKREKEYYSIDVGDSTFTVLKRYQNLRPIGSGAQGIVCSAYDHVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERLSYLLYQMLCGIKHLHAAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAATGLLMTPYVVTRYYRAPEVILGMGYQANVDVWSIGCIMAEMVRGSVLFPGTDHIDQWNKVIEQLGTPSQEFMMKLNQSVRTYVENRPRYAGYSFEKLFPDVLFPADSDHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEVEAPPPAITDKQLDEREHSVEEWKELIYKEVLEWEERTKNGVIRGQPASLAQVQQ
What is the function of this protein?
Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity.  May play a role in the regulation of the circadian clock.
What are the official names of this protein?
Mitogen-activated protein kinase 8, MAP kinase 8, MAPK 8, Stress-activated protein kinase JNK1, c-Jun N-terminal kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Synapse.
Protein: CAPSD_TGMVY
Sequence: MPKRDAPWRLMAGTSKVSRSANYSPRGSLPKRDAWVNRPMYRKPRIYRSLRGPDVPKGCEGPCKVQSYEQRHDISLVGKVMCISDVTRGNGITHRVGKRFCVKSVYILGKIWMDENIKLKNHTNSVMFWLVRDRRPYGTPMDFGQVFNMFDNEPSTATVKNDLRDRFQVIHRFHAKVTGGQYASNEQALVRRFWKVNNNVVYNHQEAGKYENHTENALLLYMACTHASNPVYATLKIRIYFYDSITN
What is the function of this protein?
Encapsidates the viral DNA into characteristic twinned ('geminate') particles.  Binds the genomic viral ssDNA and shuttles it into and out of the cell nucleus.  The CP of bipartite geminiviruses is not required for cell-to-cell or systemic movement.
What are the official names of this protein?
Capsid protein, Coat protein, CP.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae capsid protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=It is actively transported into the host cell nucleus. It may be exported out of the nucleus through a nuclear export signal for cell- to-cell movement and spread (By similarity).
Protein: PSAB_NEOYE
Sequence: MATKFPKFSQALSQDPTTRRIWYGIATAHDFESHDGMTEENLYQKIFASHFGHLAIIFLWTSGNLFHVAWQGNFEQWVLNPLKVKPIAHAIWDPHFGQPALKAFSKGGSAYPVNIAYSGVYHWWYTIGMRSNQDLYSGALFLLVLSALLLFGGWLHLQPKFKPGLSWFKNNEPRLNHHLSGLFGVSSLARTGHLVHVAIPEARGQHVGWDNFTTVLPHPAGLQPFFSGNWSVYAQNPDTAQHLFGTNEGAGTAILTFLGGFHPQSQSLWLTDMAHHHLAIAVVFIVAGHMYRTNWGIGHNLKDILDAHRPPSGRLGAGHKGLFDTITNSLHIQLGLALASLGVITSLVAQHMYAMPPYAFMAKDFTTQASLYTHHQYIAGFLMVGAFAHGAIFFVRDYDPEQNKDNVLARMLEHKEAIISHLSWVTLFLGFHTLGLYVHNDTMIAFGTPEKQILIEPVFAQWIQASSGKALYGFDVLLSSSTNIATQAGSNIWLPGWLEAINSGKNSLFLTIGPGDFLVHHAIALGLHTTTLILVKGALDARGSKLMPDKKDFGYSFPCDGPGRGGTCDISAWDAFYLAVFWMLNTIGWVTFYWHWKHITIWQGNATQFNESSTYLMGWFRDYLWLNSSPLINGYNPYGMNNLSVWSWMFLFGHLVWATGFMFLISWRGYWQELIETLAWAHERTPLANLIRWKDKPVALSIVQARLVGLAHFSVGYVLTYAAFVLASTAGKFG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2, PSI-B, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein.
Protein: Y1562_RICRO
Sequence: MVNFNQFLKQAQSMQKKMQEAQEQMANARYTGKAGGGLVEVIATGKGEVEKISIDESLLKAEEKEMLEDLIKVAFNNAQQKCDEDSQNSLSGALNGMRLPPGFKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein RrIowa_1562.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: MOCOS_DROAN
Sequence: MTLYSPEFSESEQSKIDAEFSRLTENKSVYLDHAGTTLYAESQVKAAAEQLQRNVICNPHTCRLTGDFVDQVRYKVLEFFNTTSEDYHVIFTANATASLSLVAENFDFGSFGNFHFCQENHTSVLGMRERVSHAKGIYMLTEREITGCSLQNGSSKEKPTDPGRSLVTFSAQCNFSGYKIPLDAIGNIQENGLHTPGKHIWGTEGKTSNNDYYICLDAASFVATNPLDLKRYRPDFVCLSFYKIFGYPTGVGALLVSKRGAEAFRDRKFFGGGTINYAYPHTMEYQLRESFHQRYEDGTLPFLAIVGLLEGFRTLERIVPKTKELATMERISRHVHGLAKYLEDQLKQLKHPNGEPLIQLYNKAGYQDRTRQGGIVAFNVRTDSGDYVGFGEIACVAALHGILLRTGCFCNIGACQYYLGLDGDAMDAIYKRAGRICGDYFDLIDGQPTGAVRVSFGYMTTIHDVEELLKMLRSSYLATKPQQRILFIEEQAGQLPPVLQKRVQNLRPKLLQMAIFPVKSCAAFKIEGYLKSWPLTDQGLKYDREWMIVDMNGMALTQKRCTELCLIRPLIKNDVLELHFGDSCVSVPLSLEDQAADSAKCVSKVCRQPVEGLDCGERVAEWLSTNLGQDGLRLLRQSGQRNSSKDQQKLSLVNQAQFLLVNRSSVRSLQFEEPLDDTVDRFRANIIIDTGLAFEELSFKQLSIGKVQFQVQGPCQRCDMICINQKTGERSPETLTTISRLQSGRMRFGIYITRISKDTGDLQLSCGDTVLVE
What is the function of this protein?
Sulfurates the molybdenum cofactor.  Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.
What are the official names of this protein?
Molybdenum cofactor sulfurase, MCS, MOS, MoCo sulfurase, Molybdenum cofactor sulfurtransferase, Protein maroon-like, Ma-l.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily.
Protein: PYRB_STRP2
Sequence: MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQIPYEDHPIVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDVCVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVAIAGDLDHSRVAKSNMQILKRLGSELFFAGPEEWRSQEFADYGKFVTIDEIIDQVDVMMFLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVEAPKSRIVQQMTNGVFVRMAILESVLASRNAN
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: THYX_WOLPM
Sequence: MNEATKRTIVKEIDAILYEEHKVLDHGFIRVVDYMGSDSAIVQAARVSYGKGTKQISQDEALIKYLMRHHHTTPFEMCEIKFHVKLPIFVARQWIRHRTANVNEYSARYSILDNEFYTPKPEQVAKQSDNNKQGSGEAFDPDTSKEIIDSLINDSNLVYSHYEKFIEQGLAREIARTNLMLNYYTQFYWKIDLHNLLHFLKLRADKHAQYEIRVYAEVMLDIIKKWVPLAYNAFVEYCLESACISRTGLEIIRKLIKGENVTREESNIGKREWGELMSILDKQS
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
What are the official names of this protein?
Flavin-dependent thymidylate synthase, FDTS, FAD-dependent thymidylate synthase, Thymidylate synthase ThyX, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase ThyX family.
Protein: Y3559_CHRVO
Sequence: MKSKKQARAACPCGGGELAACCGRYLGPDASPAPTAQALMRSRYSAYALGLEDYLLATWHPSTRPEALHLDEDAGVVKWIGLEVKRCEAGSERDAEGVVEFVARCKVGGKAERMHETSRFLREDGRWYYVSGLVA
What are the official names of this protein?
UPF0225 protein CV_3559.
What is the protein family that this protein belongs to?
Belongs to the UPF0225 family.
Protein: RS10_PHOV8
Sequence: MSQKIRIKLKSYDHNLVDKSAEKIVRTVKATGAIVSGPIPLPTHKRIFTVNRSTFVNKKSREQFELSSYKRLIDIYSSTAKTVDALMKLELPSGVEVEIKV
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RNH2_ECO8A
Sequence: MIEFVYPHTQLVAGVDEVGRGPLVGAVVTAAVILDPARPIAGLNDSKKLSEKRRLALYEEIKEKALSWSLGRAEPHEIDELNILHATMLAMQRAVAGLHIAPEYVLIDGNRCPKLPMPAMAVVKGDSRVPEISAASILAKVTRDAEMAALDIVFPQYGFAQHKGYPTAFHLEKLAEHGATEHHRRSFGPVKRALGLAS
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLST3_ARATH
Sequence: MDSVRRTYTIMRGRHIDKRVPSKEFLSALDKAETAVRLPTGTGKDCGNPSWKRSLPHVLVASLTSLLFGYHLGVVNETLESISIDLGFSGNTIAEGLVVSTCLGGAFIGSLFSGLVADGVGRRRAFQLSALPMIVGASVSASTESLMGMLLGRFLVGIGMGIGPSVTALYVTEVSPAYVRGTYGSSTQIATCIGLLGSLFAGIPAKDNLGWWRICFWISTVPAAMLAVFMELCVESPQWLFKRGRAAEAEAVFEKLLGGSYVKAAMAELVKSDRGDDADSAKLSELLFGRSFRVVFIGSTLFALQQLSGINAVFYFSSTVFKKAGVPSASANICVGVCNLLGSTVAVVLMDKLGRKVLLIGSFAGMAVSLGLQAIAYTSLPSPFGTLFLSVGGMLLFVLSFATGAGPVPSLLLSEICPGRLRATALAVCLAVHWVINFFVGLLFLRMLEQLGSVLLNAIFGFFCVVAVIFVQKNVVETKGKSLQEIEISLLSSTQ
What is the function of this protein?
May be involved in the efflux of glucose towards the cytosol.
What are the official names of this protein?
Probable plastidic glucose transporter 3.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: UPP_LATSK
Sequence: MAKFTVLNHPLIQHKLTIIRNKNTGTKVFREVANEIAELMVYEITRDLAMEDVEVETPMGPAIEKQLSGKKLAVVPILRAGLGMVDGVLELIPAAKVGHIGMYRDEKTLQPHEYFVKLPTDIDQRQLFIVDPMLATGGSAIMAIDALKKRGATSMRLVVLVAAPEGVKAVQEAHPDVDIYAAGLDDGLNEEGYIYPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: RS211_GEOSL
Sequence: MQVSVQGNDVDKALRLLKRKLQTEGFFKEIKKRKHYEKPSVKKKRKQMEAERKRRKAQRFRKPDRD
What are the official names of this protein?
30S ribosomal protein S21 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: YNAE_BACSU
Sequence: MNLIGYIEERFQNLELIPSIYNQWGTGIHFCLGENIYQLKANEELNLKMFRIVYEQTSIIFNELFEQNDDIFLVTNMYKHKKKEKCIRKLKVYQPFLKCKNHLNQIMVKTYPYPFEINKAEEYEMQQFSLLCKPRDLRVTELLKAASNEDFPQKPKFGGYSIDYPDVFFVNITKDIIFFIYDDRGCEVIAHDFKRIRPLYEKYHDWVEEYKCM
What are the official names of this protein?
Uncharacterized protein YnaE.
Protein: RRF_STRP6
Sequence: MANAIIETAKERFAQSHQSLSREYASIRAGRANASLLDRIQVDYYGAPTPLNQLASITVPEARVLLISPFDKSSIKDIERALNASDLGITPANDGSVIRLVIPALTEETRKELAKEVKKVGENAKIAIRNIRRDAMDDAKKQEKAKEITEDELKTLEKDIQKATDDAIKEIDRMTAEKEKELLSV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS3_RHOPA
Sequence: MSSESRSASSPVAPDDIEEGVVLRPKFDAHGLVTVVATDARTGDVLMVAFMNGEALDRTIQTGEAWYYSRSRKRLWKKGETSGHIQKVLEMRVDCDQDAVWIKVDQTGGAACHTGRHSCFYRRIDRGGDGAPVLIETDSERKFDPDKVYGK
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STAD6_ORYSJ
Sequence: MAATATMAMPLANRLRCKPNTNSSSPSRTLFGRRVTMISSSRWGSAVSGSAIMSAAADVAAAVRREEDEEMRSYLSPEKLEVLTQMEPWVEEHVLPLLKPVEAAWQPSDLLPDPAVLGGEGFHAACAELRERAAGVPDLLLVCLVANMVTEEALPTYQSSLNRVRAVGDLTGADATAWARWIRGWSAEENRHGDVLNRYMYLSGRFDMAEVERAVHRLIRSGMAVDPPCSPYHAFVYTAFQERATAVAHGNTARLVGARGHGDAALARVCGTVAADEKRHEAAYTRIVSRLLEADPDAGVRAVARMLRRGVAMPTSPISDGRRDDLYACVVSLAEQAGTYTVSDYCSIVEHLVREWRVEELAAGLSGEGRRARDYVCELPQKIRRMKEKAHERAVKAQKKPISIPINWIFDRHVSVMLP
What is the function of this protein?
Introduces a cis double bond in the acyl chain of an acyl-[acyl-carrier protein].
What are the official names of this protein?
Acyl-[acyl-carrier-protein] desaturase 6, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HIS7_ECOLI
Sequence: MSQKYLFIDRDGTLISEPPSDFQVDRFDKLAFEPGVIPELLKLQKAGYKLVMITNQDGLGTQSFPQADFDGPHNLMMQIFTSQGVQFDEVLICPHLPADECDCRKPKVKLVERYLAEQAMDRANSYVIGDRATDIQLAENMGITGLRYDRETLNWPMIGEQLTRRDRYAHVVRNTKETQIDVQVWLDREGGSKINTGVGFFDHMLDQIATHGGFRMEINVKGDLYIDDHHTVEDTGLALGEALKIALGDKRGICRFGFVLPMDECLARCALDISGRPHLEYKAEFTYQRVGDLSTEMIEHFFRSLSYTMGVTLHLKTKGKNDHHRVESLFKAFGRTLRQAIRVEGDTLPSSKGVL
What are the official names of this protein?
Histidine biosynthesis bifunctional protein HisB.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIR_ORYSJ
Sequence: MASSASLQRFLPPYPHAAASRCRPPGVRARPVQSSTVSAPSSSTPAADEAVSAERLEPRVEQREGRYWVLKEKYRTGLNPQEKVKLGKEPMSLFMEGGIKELAKMPMEEIEADKLSKEDIDVRLKWLGLFHRRKHQYGRFMMRLKLPNGVTTSEQTRYLASVIEAYGKEGCADVTTRQNWQIRGVTLPDVPAILDGLNAVGLTSLQSGMDNVRNPVGNPLAGIDPDEIVDTRSYTNLLSSYITSNFQGNPTITNLPRKWNVCVIGSHDLYEHPHINDLAYMPAVKGGKFGFNLLVGGFISPKRWEEALPLDAWVPGDDIIPVCKAVLEAYRDLGTRGNRQKTRMMWLIDELGMEAFRSEVEKRMPNGVLERAAPEDLIDKKWQRRDYLGVHPQKQEGMSYVGLHVPVGRVQAADMFELARLADEYGSGELRLTVEQNIVIPNVKNEKVEALLSEPLLQKFSPQPSLLLKGLVACTGNQFCGQAIIETKQRALLVTSQVEKLVSVPRAVRMHWTGCPNSCGQVQVADIGFMGCLTKDSAGKIVEAADIFVGGRVGSDSHLAGAYKKSVPCDELAPIVADILVERFGAVRREREEDEE
What is the function of this protein?
Catalyzes the six-electron reduction of nitrite to ammonium.
What are the official names of this protein?
Ferredoxin--nitrite reductase, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FABA_ECO7I
Sequence: MVDKRESYTKEDLLASGRGELFGAKGPQLPAPNMLMMDRVVKMTETGGNFDKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEGKGRALGVGEVKFTGQVLPTAKKVTYRIHFKRIVNRRLIMGLADGEVLVDGRLIYTASDLKVGLFQDTSAF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURD_COXB2
Sequence: MSSESLTVIVGLGKTGLSCAQFLAAKNQPFAVMDSREEPPEWENFIKTYPRVELIRGQFSEKLLNEAQEIILSPGVSLQEPLIAKQAAQGKSIIGDIELFARNVNKPIIAITGSNGKTTVTTVVGLMMKAAGRNVSVCGNIGEPVLEQITPEPDYYVLELSSFQLETTFSLRSQAATILNISEDHMNRYATLQDYLRAKQRIYTDCFIPIVNADEPEIWRHLPFNKKPLSFGLNNAADFSLAEHNQKTSIAYQGKILMPIQELKLNARHHLQNALAALALGTAAKIPIENMLHVLRDFSGIRHRCQWVRKYKEIDYYNDSKGTNVGATRAAIESLGQAAKGQLILIAGGQGKGADFSPLKDVVKRYVKQVILIGEDAPLLEKTLKEITVIKHADSMNEAVKRSTQAAKAGDIVLLSPACASFDMFTNYEHRGDVFTETVEAL
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CUE3_YEAST
Sequence: MLSRYNRVIEINGGNADISLPIVKFPPFKLRAQLIEKDPVVWLHLIETYVTYFEYLMQGANVELLDESTLDHLRLFLRTYLHEIADEEGKLLSLGINHDVSEQLYLLKGWIFSLIKKCGLLHLQIFGDSLWNLIKVYVRRNPDSIRGLIDGSLKPRINTQRVQLDKSYQVQQHLKQLIESGKFKRIDLRCVEDLLSAKSMQPNKFAENFFTANWIEILEALWAKGQGRGHKEARELIIISLFSVSADRLLKITKELGISNFETLALYPLLGTMLINEGVHKRLPDLKSKLLFLNLGGLSMDEGDHMSYPTSSGTEVNEEQLSALMELFPQFSKYQLSQTLLAYDNNIELVTNKIFEDPTIIEAFSREPAEEEVEPVSDGDNASFTEELSILDRGDSSKNKELDKKIISEGVPDELRNKTLTRALKLLYEADEDERDDTYDEADVNRSDPSKRIGLQEDEESYDTKDDSNEVRQDHNYHIVEAYLWNLLKEDPKLFERSKRGTKVRKTMKEMTSWSDEKIEGWCRMLERSPTRARLLEKKFMFKGNSKTGKTSYVHNRDSQNDGNVVKEQAKQKKSENIKKHEPQSTEQKKRQHAKNEKRKGARANHNRKKGHDKKLARAGNNAI
What is the function of this protein?
Involved in activation of the ribosome quality control (RQC) pathway, a pathway that degrades nascent peptide chains during problematic translation (PubMed:28757607, PubMed:28223409, PubMed:32203490).  As part of the ribosome quality control trigger (RQT) complex, recognizes HEL2-dependent ubiquitination of RPS20 on stalled ribosomes (PubMed:28757607).
What are the official names of this protein?
RQC trigger complex subunit CUE3, CUE domain-containing protein 3, Coupling of ubiquitin conjugation to ER degradation protein 3.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEF_BORPA
Sequence: MSLSNAPLGQHVAYPSQYDPGLLFPIPRATNRASLQLGATLPFTGVDLWNAYELSWLDARGKPRVAMATFSFPADSPNIVESKSFKLYLNSFNQTRLPNAQALRDRLERDLAAAAGAPVGLKFISPQRFGELNMAELDGIYIDKLDIEIDTYEPAPQLLQCAPGDEVEETLATRLLKSNCPVTGQPDWASLQVRYRGRPIDRAALLKYVVSFRQHAEFHEHCVERIFGDIMRACQPRQLTVYARYTRRGGLDINPWRSNFESAPPADVRTARQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NHAC_BACSU
Sequence: MDSQKKLTFPLAVGLFIFMLCIIISCLFLLHVEPHIPLFLSVVMLSAAALWFGFPWKSIEKGIVDGIKNGVQPIIVLALIGILIGAWMYSGAIPTMTVYALSFIEPSHLLLTALFSCMIISTLVGSSLTTVSTIGVALIGVASAAGVPLEWTAGAVICGACFGDKMSPMSDTTNFAAGIGEIPIFEHIRHMMGTTIPALLITVVLFYFLGSSVSADAASTDNIQQVITGIKDAANVTPWALLSPLLVVLLAMKRVSVIPVLTAGIISSGILTAIFVPYSSLQAFMTALQNGTTFETDNEAAAKIINRGGLQSMMGSVSLIMIAFALGGLMEKIGLISALLEGVMKGIRSKGRLVAATVCSSIGVNLATGEQYLSILIPGQSFKSLYDKRNIQRKFLTRSLEDGGTLINPLIPWGVSGAFMASALGVPVIDYIPFTFFLYISPMISILIGFVKK
What is the function of this protein?
Is a secondary, electrogenic Na(+)/H(+) antiporter that catalyzes Na(+) uptake and proton efflux.  Makes modest contributions to pH homeostasis in the alkaline range of pH but is not contributor to Na(+) resistance.  Appears to have a repressive effect on growth and on alkaline phosphatases production in the presence of sodium, by affecting the transcription of the phoP/phoR two-component regulatory system.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaC, Sodium/hydrogen antiporter, Sodium/proton antiporter.
What is the protein family that this protein belongs to?
Belongs to the NhaC Na(+)/H(+) (TC 2.A.35) antiporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1960_SULIY
Sequence: MPISGVDDGYFPLSYKGGKGKTALVVVTFYDYEMIDLDWGLITVDGNDATDVLKQLRKGDIVILDGVIFAGFNYIVPYSDNMIFFYSKMPKVDLIKNALMKHFQADTERVREILYVLNNLKQIPTKRGNVFLYSTVELSLAKSIIEKYQIYSKIPEVLKSAHVIASSLGRFLARYKKTV
What are the official names of this protein?
UPF0215 protein YG5714_1960.
What is the protein family that this protein belongs to?
Belongs to the UPF0215 family.
Protein: RL2_NEIG2
Sequence: MAIVKMKPTSAGRRGMVRVVTEGLHKGAPYAPLLEKKNSTAGRNNNGHITTRHKGGGHKHHYRVVDFKRNKDGISAKVERIEYDPNRTAFIALLCYADGERRYIIAPRGIQAGVVLVSGAEAAIKVGNTLPIRNIPVGTTIHCIEMKPGKGAQIARSAGASAVLLAKEGAYAQVRLRSGEVRKINVDCRATIGEVGNEEQSLKKIGKAGANRWRGIRPTVRGVVMNPVDHPHGGGEGRTGEAREPVSPWGTPAKGYRTRNNKRTDNMIVRRRYSNKG
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: LAFA_LACJO
Sequence: MKQFNYLSHKDLAVVVGGRNNWQTNVGGAVGSAMIGATVGGTICGPACAVAGAHYLPILWTAVTAATGGFGKIRK
What is the function of this protein?
Heat stable bacteriocin active against Enterococcus faecalis and other Lactobacilli.
What are the official names of this protein?
Bacteriocin lactacin-F subunit LafA.
What is the protein family that this protein belongs to?
Belongs to the bacteriocin class IIB family.
Protein: DAPA_SYNJB
Sequence: MNFGRVLTAMVTPFTDEGELNYDEAARLADYLATHGSDGLVVCGTTGESPTLTWQEEYELFRVVRDAVAGRAKVIAGTGSNSTREAIEATKKAAQLGLDGSLQVVPYYNKPTQAGLYEHFKAIAQASDLPILLYNIPSRTGASLQPETVAQLAELETVVAIKEASGMMDVASEIRRLTPSRFAIYSGDDSLTLPLLSLGGSGVVSVASHLVGLQLQELIQSYIRGQHDQALAHHLRLFPLFKVLFIETNPVPIKAALEMQGWRVGRARLPLAPLQPSSLQVLRQVLEEMGLLAESKGSEQMATKVS
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSXB_SHIFL
Sequence: MNAIWIAVAAVSLLGLAFGAILGYASRRFAVEDDPVVEKIDEILPQSQCGQCGYPGCRPYAEAISCNGEKINRCAPGGEAVMLKIAELLNVEPQPLDGEAQELTPARMVAVIDENNCIGCTKCIQACPVDAIVGATRVMHTVMSDLCTGCNLCVDPCPTHCISLQPVAETPDSWKWDLNTIPVRIIPVEHHA
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit B, Rsx electron transport complex subunit B.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane.