PharMolix/UniProtQA huggingface dataset:
Protein: RS3_BRUME
Sequence: MGQKINPIGLRLGVNRTWDSRWYANTGEYGKLLHEDVKIREFLTEELKQAAISKIVIERPHKKCRVTIHSARPGIIIGKKGADIEKLRKKLSEMTNADTSLNIVEVRKPEVDATLIAQSIAQQLERRVAFRRAMKRAVQSAMRLGAEGIRINCSGRLGGAEIARMEWYREGRVPLHTLRADIDYGTAEAKTAYGICGVKVWVFKGEILEHDPMASERRAVEGDNQGSSSNRRRENA
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RL34_LIMRD
Sequence: MKRTFQPKKRHRARVHGFRKRMSTSNGRKVLARRRQKGRKVLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: KUP_GEOUR
Sequence: MKKHTESYWEGVVKSMGLVFGDIGTSPIYTLTVIFALTKPTEANVFGILSMVVWTLIILVTVEYAWLAMSLGRKGEGGTIVLKEILIRLLKPGRQIAFVGFLSFVGVSLLLGDGVITPAISILSAVEGLVLIPGLESMRLGTLILIAALIAVVLFIFQFKGTDKVAAAFGPLMVLWFGALTVSGLVSIATFPKILGAVSPHYAINFFRDNGISAFFVLSEVILCATGGEALYADMGHLGRRPIIRAWYFVFVALIINYLGQGAFALQHGDAKNFLFNMVQGQSQLLYIPFLILTILATVIASQALISGVFSIVYQGITTRIMPLMKVDYTSSHLKSQIYIGSVNWFLMLLVIFIMLIFQKSENLAAAYGLAVTGTMTITGIMMTIIFAHTTKKWKVPVAVAVTIVDVVFLISNLNKLPHGGYWSIILASVPFATILIWTKGQQALYRALKPLDMETFLLSYEQIYAKGKNITGTGLFFTREWNVIPPYVVHCIIRSNIIYERNIFISIVRTDEPFGLKSELKTGFGPGLDAFEIKAGYMEVIDIEKLLKKHDIQEKVIFYGIEDIATMNPVWRVFSVIKKLTPNFVQFNKLPASKLQGVVTRVEM
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HMSD_HUMAN
Sequence: MSISSALAMVFMGAKGNTAAQMSQALCFSKIGGEDGDIHRGFQSLLVAINRTDTEYVLRTANGLFGEKSYDFLTGFTDSCGKFYQATIKQLDFVNDTEKSTTRVNSWVADKTKGENILLFYFDNILNSFIVSSLQNCQI
What is the function of this protein?
Putative serine protease inhibitor.
What are the official names of this protein?
Serpin-like protein HMSD, Minor histocompatibility protein HMSD, Minor histocompatibility serpin domain-containing protein.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted.
Protein: AK1_ARATH
Sequence: MAATRVRCCHSNAAFTRLPLTRHRNSPTLPISLNRVDFPTLKKLSLPIGDGSSIRKVSGSGSRNIVRAVLEEKKTEAITEVDEKGITCVMKFGGSSVASAERMKEVADLILTFPEESPVIVLSAMGKTTNNLLLAGEKAVSCGVSNASEIEELSIIKELHIRTVKELNIDPSVILTYLEELEQLLKGIAMMKELTLRTRDYLVSFGECLSTRIFAAYLNTIGVKARQYDAFEIGFITTDDFTNGDILEATYPAVAKRLYDDWMHDPAVPIVTGFLGKGWKTGAVTTLGRGGSDLTATTIGKALGLKEIQVWKDVDGVLTCDPTIYKRATPVPYLTFDEAAELAYFGAQVLHPQSMRPAREGEIPVRVKNSYNPKAPGTIITKTRDMTKSILTSIVLKRNVTMLDIASTRMLGQVGFLAKVFSIFEELGISVDVVATSEVSISLTLDPSKLWSRELIQQELDHVVEELEKIAVVNLLKGRAIISLIGNVQHSSLILERAFHVLYTKGVNVQMISQGASKVNISFIVNEAEAEGCVQALHKSFFESGDLSELLIQPRLGNGSPVRTLQVEN
What is the function of this protein?
Involved in the first step of essential amino acids lysine, threonine, methionine and isoleucine synthesis via the aspartate-family pathway.
What are the official names of this protein?
Aspartokinase 1, chloroplastic, Aspartate kinase 1.
What is the protein family that this protein belongs to?
Belongs to the aspartokinase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MATK_LATCL
Sequence: MEQIRRYLQLERFQQHDFLYPXFFQEYIYVFAHGRGFSRSIWSENENTGYDNKSSLRVMKRLITRMYQQNNFIILPNDFNKKNPFLAKKKFFYSQIIAEGFAFIVEIPFSLRFISYLEGKKKIVKSQNLRSIHSIFPFLEDNFSHLNFVLDILILHPVHVEILVQILRYWVKDASSLHLLRFFLNKYWNSLITPNKASSSLSKKNKRLFVFLYNSHVGGYESSFVFIRNQSSHLGSTPFGVLLERIYFYGKIERLVNVFVKVKDFRTNLWFVKEPYIHYIRYQRKWILASKGTFLFVKKWKCYLIIFWQWHFSLWFYPRRIYINQLSNHYFEFLGYLSNLRMTPSVVRSQSLENTFIINNAIKKIDNFVPIISMIASLAKAKFCNVFGHPISKPVRADLSDSNIIDQFGCICRKFFHYYSGSSKKKSLYRIKYILRLACARTLARKHKSTVRTFLKRLGSELLEEFLLSEEDVLFLTFPKASSSLQGVYRSRIWYLDIIYINDLVDHKYKL
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid.
Protein: UCRIA_SYNY3
Sequence: MDNTQAIAPPSYSRRQLLNFLAGTTVAVTASAGAYAMGKFFVPPAEKGGAGGGIIAKDVLGNPIPASQILAEAPGTRALVAGLAGDPTYLIVKEDGSLDSIGIVDSCTHLGCTFPWNGNDQEFQCPCHGSRYHPDGSVARGPAPLPLKIVQVAVVDDQIFISPWTDLDPRTGEKPWWV
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex iron-sulfur subunit 1, Plastohydroquinone:plastocyanin oxidoreductase iron-sulfur protein 1, ISP 1, RISP 1, Rieske iron-sulfur protein 1.
What is the protein family that this protein belongs to?
Belongs to the Rieske iron-sulfur protein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein. Note=The transmembrane helix obliquely spans the membrane in one monomer, and its extrinsic C-terminal domain is part of the other monomer.
Protein: ARGB_BACHK
Sequence: MNDYIVVKCGGSMLDQLNDVFFDCIKKLQQQYKVVIVHGGGPEIDAKLKDCNINVEKRDGLRVTPKEVMDVVQMVLCGSTNKKFVMNLQKHNLLAVGCSGCDGKLLQVQPVSEEIGYVGEVSYVETALLKGLINMNYIPVIAPIGIHDNEIYNINADTAAAGIAAALSAKELILITDVDGILHEGKLVKKTDESEIATFIEKGVITGGMIPKVQAALASLKMGVQKISIVNGTKDFTEDTGECIGTTVTRGVSIV
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3NO21_NAJKA
Sequence: LTCLNCPEMFCGKFQICRNGEKICFKKLHQRRP
What is the function of this protein?
Possible voltage-gated potassium channel (Kv) blocker.  Decreases amplitude of compound action potential and conduction velocity in toad sciatic nerve.  Has only mild anticoagulant activity even at a concentration of 5ug/ml.  Shows no cytotoxicity towards human cell lines.
What are the official names of this protein?
Neurotoxin Nk-3FTx.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Ancestral subfamily. Orphan group II sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPB_CLOP1
Sequence: MSNNIGKVVQVIGPVVDIKFANDELPNIFNAIHIKMDDGKILVCEVEQHVGDDIVRTIAMEATEGLRRGVEAVDTGAPISVPVGECVLGRIFNVLGKPLDSGAEVNNEEKYPIHRPAPSFEEQSVVPQMFETGIKVIDLLAPYQRGGKIGLFGGAGVGKTVLIQELINNIAKEHGGLSVFTGVGERSREGNDLYYEMMESGVIKNTALVFGQMNEPPGARMRVALTGLTMAEYFRDQGQDVLLFIDNIFRFSQAGSEVSALLGRIPSAVGYQPTLATEMGALQERITSTTHGSITSVQAVYVPADDLTDPAPATTFNHLDAKTVLSRSIAEIGIYPAVDPLDSSSRILDPRVVGEEHYEVASKVKHILERYKELQDIIAILGVDELADEDKLIVARARRIQKFLSQPFTVAEQFTGMQGRYVPIKETIRGFKEILEGKHDNVPESAFLFAGTIEEVLEKARAMAQ
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RSMG_BACCZ
Sequence: MNIEQFQSMLEEKGITLSSRQLEQFEIYFETLVEWNEKMNLTAITEKEEVYLKHFFDSITAAFYYDFSKPFSICDVGAGAGFPSIPLKICFPHLKVTIVDSLQKRINFLNHLAQKLELSDVAFCHDRAETFGKKEGVREAYDIVMARAVARLSVLSELCLPLVKVGGTFIAMKGAAAKEEIENGKYALEVLGGDLKEMSTFQLPFEESERNILLIEKKRKTPKKYPRKPGTPNKLPIEK
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 5DNU_YERE8
Sequence: MSHFFAHLSRLKLINRWPLMRNVRTENVSEHSLQVAFVAHALAIIKNRKFNGNLNADRIALLAMYHDASEVITGDLPTPIKYYNPQIAHEYKKIEKVAQQKLIEMLPEELQHDFRCLLDEHYYSEEEKALVKQADALCAYLKCLEELSAGNNEFIQAKVRLEKTLAMRQSPEMDYFMEVFVPSFSLSLDEISLDSLD
What is the function of this protein?
Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
What are the official names of this protein?
5'-deoxynucleotidase YE1340, 5'-deoxyribonucleotidase, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the 5DNU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_LACZE
Sequence: MAKEIKFSEDARAAMLRGVDQLANTVKTTLGPKGRNVVLDKSYGSPEITNDGVTIAKSIDLEDHYENMGAKLVAEVASKTNDIAGDGTTTATVLAQSIIREGMKNVTAGANPVGIRTGIEKATKAAVDELHKISHKVNGKKEIAQVASVSSSNTEVGSLIADAMEKVGHDGVITIEESKGIDTELSVVEGMQFDRGYLSQYMVTDNDKMEADLDDPYILITDKKISNIQDILPLLQEIVQQGKALLIIADDVAGEALPTLVLNKIRGTFNVVAVKAPGFGDRRKAQLEDIATLTGGTVISSDLGLDLKDTKLEQLGRAGKVTVTKDNTTIVDGAGSKDAIAERVNIIKKQIDDTTSDFDREKLQERLAKLAGGVAVVKVGAATETELKERKYRIEDALNATRAAVEEGYVAGGGTALVDVLPAVAALKEEGDVQTGINIVLRALEEPVRQIAENAGKEGSVIVEQLKKEKQGVGYNAATDEWEDMAKSGIIDPTKVTRSALQNAASVAALMLTTEAVVADKPDPNANNNAAAGANPAAGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_RICM5
Sequence: MDKEHLKKNLQGKMEKALKVLDHELKGLRTGRASINLLDSVTVEAYGSKMPLSQVASLSTPDARTINVQVWDKSMVSSVEKGITIANLGLTPATDGQLIRLPIPTLTEERRQELVKLAHKYGEDTKISLRNIRRDGNEELKKLEKDNVIAKDEHHSLSEQVQKLTDDYSSKVDSVIKQKEQEIMTV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBL24_ARATH
Sequence: MKLKLSSISMNHKNVLLIKLISAILISFFAFRLFILHSSEFSPIFASVTGKFEARFLPPEIIVPENEDLIPQDIEVEKCDLFAGKWIPDSVGPIYTNKSCGSLIDGHQNCITNGRPDLDFLYWKWKPHDCLLPRFDPRRFLQLMRHKSWAFIGDSISRNHVESLLCMLSTIEEPVEVYHDMEYKSKRWHFPLHNLTVSNIWSPFLVQAAIFEDSNGVSTASVQLHLDRLDETWTSLMPSFDYAIISTGKWFLKSAIYHENAKLVGCHNCQEKPHIEELGFDYAYNASLHNVMDFLAAEDNSKGTVFFRTSTPDHFQNGEWHSGGTCKQTEPVSDEEIEIKDVHKILKDIEIDQFKRAVREKTNQDGGNLKLLDFTRMLLTRPDGHPGEYRQFRPFDKDKNAKVQNDCLHWCLPGPFDYLNDVILETIVNG
What is the function of this protein?
May act as a bridging protein that binds pectin and other cell wall polysaccharides.  Probably involved in maintaining esterification of pectins (By similarity).  May be involved in the specific O-acetylation of cell wall polymers (By similarity).
What are the official names of this protein?
Protein trichome birefringence-like 24.
What is the protein family that this protein belongs to?
Belongs to the PC-esterase family. TBL subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: BGLM_NEOFI
Sequence: MHSNLGLAGLAGLLATASVCLSAPADQNITSDTYCYGQSPPVYPSPEGSGTGSWAAAYAKAKNFVAQLTPEEKVNLTAGTDANNGCSGNIAAIPRLNFPGLCVSDAGNGLRGTDYVSSWPSGLHVGASWSKALAKQRAIHMAKEFRKKGVNVILGPVVGPLGRVAEAGRNWEGFSNDPYLSGALVYETVDGAQSVGVATCTKHYILNEQETNRNPGTEDGVDIAAVSSNIDDKTMHELYLWPFQDAVLAGSASIMCSYNRVNNSYGCQNSKTLNGLLKTELGFQGYVMTDWGAQHAGIAGANAGLDMVMPSTETWGANLTTAISNGTMDASRLDDMAIRIIASWYQMNQNSDSPSPGVGMPTNMYAPHQRVIGREASSKQTLLRGAIEGHVLVKNTNSALPLKSPQLLSVFGYDAKGPDALKQNFNWLSYSPAIQENHTLWVGGGSGANNAAYVDAPIDAIKRQAYEDGTSVLYDLSSEDPDVDPTTDACLVFINSYATEGWDRPGLADKSSDSLVKNVAGKCANTIVTIHNAGIRVIGDWIDHENVTAVIFAHLPGQDSGRALVELLYGRANPSGKLPYTVAKKAEDYGSLLHPSLPETPYGLFPQSDFDEGVYIDYRAFDKANITPQFEFGFGLSYTAFEYSGLRISNPKKSPQYPPSAAIQQGGNPHLWDKTVTVSAEVKNTGRVAGAEVAQLYIGIPNGPVRQLRGFEKVDVSAGETTQVKFALNRRDLSTWDVEAQQWSLQRGTYRVYVGRSSRDLPLTGSFTL
What is the function of this protein?
Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass.  Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).
What are the official names of this protein?
Probable beta-glucosidase M, Beta-D-glucoside glucohydrolase M, Cellobiase M, Gentiobiase M.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: UBP10_BOVIN
Sequence: MALRSPQYIFGDFSPDEFNQFFVTPRASVELPPYGGTVLCGAQAADDLPDGHDYQRIEFGVNEVIEPSDTLPRTPNYSISSTLNPQAPEFILSCTTSKKLPDDIDKEVNYSSANCQYPGPALALDGGSPAEAEALENDGVSGGLGQRERKKKKKRPPGYYSYLKDGGEGGPSAEALVNGHAGPAVSNSVGAEDTDLMGDVPTAGTPRTWGSPQDATDFVSDAGPAGAFPGALDGGARTAGQLEGCPGADSEASCLPAEAGRDTLLRTAVAQPSVGTDTTENLGVTNGQILESLGEGTAANGVELHTVESSDSDPAKAESAPPPADAPASAAGTVPASQPAKSWASLFHDSKPSSSSLPVVSVETKYSPPATSPLVSEKQAEVKEGLVPVSEDPVAIKIAELLENVTLIHKPVSLQPRGLINKGNWCYINATLQALVACPPMYHLMKLIPLYSKVQRPCTSTPMIDSFVRLMNEFTNMPVPPKPRQALGDKIVRDIRPGAAFEPTYIYRLLTVIKSSLSEKGRQEDAEEYLGFILNGLHEEMLNLKKLLSPNNDKLTISNGPKSHSVNEDEQEEPGEGSEDEWEQVGPRNKTSVTRQADFVQTPITGIFGGHIRSVVYQQSSKESATLQPFFTLQLDIQSDKIRTVQDALESLVARESVQGYTTKTRQEVEISRRVTLEKLPPVLVLHLKRFVYEKTGGCQKLIKNIEYPVDLEISKELLSPGVKNKNFKCHRTYRLFAVVYHHGSSATGGHYTTDVFQIGLNGWLRIDDQTVKVVSQQQVVRPAAERTAYLLYYRRVDLL
What is the function of this protein?
Hydrolase that can remove conjugated ubiquitin from target proteins such as p53/TP53, BECN1, SNX3 and CFTR.  Acts as an essential regulator of p53/TP53 stability: in unstressed cells, specifically deubiquitinates p53/TP53 in the cytoplasm, leading to counteract MDM2 action and stabilize p53/TP53.  Following DNA damage, translocates to the nucleus and deubiquitinates p53/TP53, leading to regulate the p53/TP53-dependent DNA damage response.  Component of a regulatory loop that controls autophagy and p53/TP53 levels: mediates deubiquitination of BECN1, a key regulator of autophagy, leading to stabilize the PIK3C3/VPS34-containing complexes.  In turn, PIK3C3/VPS34-containing complexes regulate USP10 stability, suggesting the existence of a regulatory system by which PIK3C3/VPS34-containing complexes regulate p53/TP53 protein levels via USP10 and USP13.  Does not deubiquitinate MDM2.  Deubiquitinates CFTR in early endosomes, enhancing its endocytic recycling.  Involved in a TANK-dependent negative feedback response to attenuate NF-kappaB activation via deubiquitinating IKBKG or TRAF6 in response to interleukin-1-beta (IL1B) stimulation or upon DNA damage.  Deubiquitinates TBX21 leading to its stabilization.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 10, Deubiquitinating enzyme 10, Ubiquitin thioesterase 10, Ubiquitin-specific-processing protease 10.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. USP10 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Early endosome. Note=Cytoplasmic in normal conditions (By similarity). After DNA damage, translocates to the nucleus following phosphorylation by ATM (By similarity).
Protein: CR1L_HUMAN
Sequence: MAPPVRLERPFPSRRFPGLLLAALVLLLSSFSDQCNVPEWLPFARPTNLTDDFEFPIGTYLNYECRPGYSGRPFSIICLKNSVWTSAKDKCKRKSCRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDRIICGLPPTIANGDFTSISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPAAPRCEVKSCDDFLGQLPNGHVLFPLNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCERKSCETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSMKPPICQQIFCPNPPAILNGRHTGTPLGDIPYGKEVSYTCDPHPDRGMTFNLIGESTIRRTSEPHGNGVWSSPAPRCELPVGAGSHDALIVGKFYEVFAEEFCHL
What are the official names of this protein?
Complement component receptor 1-like protein, Complement C4b-binding protein CR-1-like protein.
What is the protein family that this protein belongs to?
Belongs to the receptors of complement activation (RCA) family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane. Secreted. Note=Predominantly found in association with the membrane fraction, but also located in the cytoplasm and in the supernatant.
Protein: COBD_CALS4
Sequence: MKEGEKMKPYEHGGNIYDYQGNLIDFSSNINPLGPPEWIWEAIKEVDLSRYPDIKYRRLKEAIAEYVGCDRENIIVGNGAAELIHLFARAFKLKKPLIPSPSFLEYERAVKLNGGEPVYLKLEEEEGFRVNFAKVISKIEEADGLILGNPNNPTGQGIIREEIGILLKKAELMNIPVLIDEAFIEFMKDYKKYEALPLVKKHDKLFVVRAVTKFFGMPGIRLGYGIGSPSLIQKLEEYKEPWTVNAFAEAVGRWLFKDREYIEKTREYVNAEIEHMLFSLRTIDYLVAFDTKVNFILLKLKAGTVDEVKEKLLKKGILIRDASNFRYLDKRFFRVAVKRREDNMCLIEALRGLYEEGVMPDKERVVV
What is the function of this protein?
Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.
What are the official names of this protein?
Putative threonine-phosphate decarboxylase, L-threonine-O-3-phosphate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
Protein: CALM_PLEOS
Sequence: MADQLSEEQISEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMRDTDSEEEIKEAFKVFDKDGNGYISAAELRHVMTNLGEKLTDNEVDEMIREADVDGDGQINYEEFVKMMLSK
What is the function of this protein?
Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+).  Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity).
What are the official names of this protein?
Calmodulin, CaM.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
Protein: TYS1_ENCCU
Sequence: MPQDPRHPEHQYLDLVKHILENGARRMDRTGTGTLSVFGATMRFSLEDNTFPLLTTRRVFYRGVVEELLFFLRGETDSKVLEKKGVRIWEKNGAKQFLQSVGIDREEGDLGPIYGFQWRHFGARYETSASSYEGKGVDQIASAIAAIRANPASRRIVVSAWNPTDLGSMALPPCHVLFQFNVTDGKLSCAMYQRSGDMGLGVPFNIASYSLLTILVAHLTGLQPGEFVHFLGDAHVYLDHVDSLRQQIQRPPRAFPKLFVSPKGPRTEPEHFQYEDFELVGYDPHPAIKMNMSA
What are the official names of this protein?
Thymidylate synthase 1/2, TS 1/2, TSase 1/2.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family.
Protein: METK_SHEPA
Sequence: MAKHLFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGMVMVGGEVTTSAWVDIEEITRKTVRDIGYTHSDMGFDADSCAILNVIGKQSPDINQGVDRADPKEQGAGDQGLMFGYANNETDVLMPAPITYSHKLVKRQSEVRKDKTLPWLRPDAKSQVTFAYNSDGSIAGIDAVVLSTQHSEDVTQADLIEGVMETIIKPVLPAKWLSKDTKYFINPTGRFVIGGPVGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVSYAIGVAEPTSISIETFGTAKVGEELLIDLVRRHFDLRPYGLTEMLNLARPIYQATAAYGHFGRNEFPWEATDKVDALRADAGL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF6_MESMA
Sequence: MKVIAILFLLAFVLCTMEITMVEAGFGCPLFQFACDSHCRGMGRKGGYCGGNFKLTCICVVK
What is the function of this protein?
Antibacterial peptide active against Gram-positive bacteria, but not on Gram-negative bacteria (By similarity).  Has also weak blocking activity on Kv1. 1/KCNA1, Kv1. 2/KCNA2, Kv1. 3/KCNA3, KCa3. 1/KCNN4/IK, KCa2. 3/KCNN3/SK3 and Kv11. 1/KCNH2/ERG1 channels (tested at 1 uM) (By similarity).  It inhibits potassium channel current by interacting with the pore region (By similarity).
What are the official names of this protein?
Defensin BmKDfsin6.
What is the protein family that this protein belongs to?
Belongs to the invertebrate defensin family. Type 2 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: EMP47_YEAST
Sequence: MMMLITMKSTVLLSVFTVLATWAGLLEAHPLGDTSDASKLSSDYSLPDLINARKVPNNWQTGEQASLEEGRIVLTSKQNSKGSLWLKQGFDLKDSFTMEWTFRSVGYSGQTDGGISFWFVQDSNVPRDKQLYNGPVNYDGLQLLVDNNGPLGPTLRGQLNDGQKPVDKTKIYDQSFASCLMGYQDSSVPSTIRVTYDLEDDNLLKVQVDNKVCFQTRKVRFPSGSYRIGVTAQNGAVNNNAESFEIFKMQFFNGVIEDSLIPNVNAMGQPKLITKYIDQQTGKEKLIEKTAFDADKDKITNYELYKKLDRVEGKILANDINALETKLNDVIKVQQELLSFMTTITKQLSSKPPANNEKGTSTDDAIAEDKENFKDFLSINQKLEKVLVEQEKYREATKRHGQDGPQVDEIARKLMIWLLPLIFIMLVMAYYTFRIRQEIIKTKLL
What is the function of this protein?
Involved in the secretion of glycoproteins and in nucleus architecture and gene silencing.  Required for the endoplasmic reticulum exit of EMP46.
What are the official names of this protein?
Protein EMP47, 47 kDa endomembrane protein, Endosomal P44 protein.
What is the protein family that this protein belongs to?
Belongs to the EMP46/EMP47 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: NADK_BUCBP
Sequence: MKYYFSSIGIVGHPRYDSALNTHKLLHSWLVNKGYNVIIENKVAHKLRLKNINFDSLANIGKKCDLAIVVGGDGNMLCAARILSCYNIKIIGINRGNLGFLTDLNPDTAFQQLYNVLSGEYFIEKRFLLEVKIVKENGTALINTAINEVVLHAGHVAHMIDFEVYINNEFAFSQRSDGLIISTPTGSTGYSLSAGGPILVSSLEAMVLIPMFPHTLSSRPLVINSTSIVYLKFKKHIHSELKISCDSQVILPLNSKDNIFVKKSKKFLCLLHPKNYNYFNVLSSKLNWSKRF
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK22_HELAN
Sequence: MLNKRTTEVYALGQHISMSAHKARRVIDQIRGRSYEETLMILELMPYRACYPIFKLVYSAAANASSNMGSNEANLVISKAEVNKGTIMKRLKPRARGRSFAIQKPTCHITIVMKDISLDEYIDTDSIAWSQNKKKDTTMSYYDMYSNGGTWDKK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.