PharMolix/UniProtQA huggingface dataset:
Protein: LRRN3_HUMAN
Sequence: MKDMPLRIHVLLGLAITTLVQAVDKKVDCPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLLTFPARLPANTQILLLQTNNIAKIEYSTDFPVNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSNPIRCDCVIRWMNMNKTNIRFMEPDSLFCVDPPEFQGQNVRQVHFRDMMEICLPLIAPESFPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEGTLDINGVTPKEGGLYTCIATNLVGADLKSVMIKVDGSFPQDNNGSLNIKIRDIQANSVLVSWKASSKILKSSVKWTAFVKTENSHAAQSARIPSDVKVYNLTHLNPSTEYKICIDIPTIYQKNRKKCVNVTTKGLHPDQKEYEKNNTTTLMACLGGLLGIIGVICLISCLSPEMNCDGGHSYVRNYLQKPTFALGELYPPLINLWEAGKEKSTSLKVKATVIGLPTNMS
What are the official names of this protein?
Leucine-rich repeat neuronal protein 3, Neuronal leucine-rich repeat protein 3, NLRR-3.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: DCA10_DANRE
Sequence: MSSGHPSDNEEPRADLLREEEEEEEEEEDSDEDRGSTRPASPQATRECAGTQGSSRPEVTADGGTGSASGSGCRGSGACDSLFSWICRRKIRRGPYVDPARDHFRTMTRLYSSMSPAADSVNLSTQTHGAVFNLEYSPDGSVLTVACEQTEVLLFDPVSSRHIKTLVEAHEDCVNNIRFLDNRLFATCSDDTTIALWDLRKLNSKVCSLHGHASWVKNIEYDTHTRLLVTSGFDGNVITWDTNRFTEDGCPHKKFFHTRYLMRMRLTPDCSKMLISTSSGYLLILHDLDLTQSLEVGSYRILRARRPPLSTEGSSAGSRSGGPRHTIDNKNHPHREGLSPRNSLEVLTPEIPGERDRGNCITSLQLHPKGWATLLRCSSNMDDQEWTCVYEFQEGAPPRPPVSPRCSLRLTHYIEEANVGRGYIKELCFSPDGRLICSPYGYGVRLLAFDENCAELVDCMPVRTAQLREVRSIYSHSDVVLTSKFSPTHCQFASGCLSGRVALYQPHF
What is the function of this protein?
May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
What are the official names of this protein?
DDB1- and CUL4-associated factor 10, WD repeat-containing protein 32.
What is the protein family that this protein belongs to?
Belongs to the WD repeat DCAF10 family.
Protein: BUD32_YEAST
Sequence: MTQEFIDKVSSYLTPDVDIAPISQGAEAIVFTTTTHPYLPRAKDSHQKYIIKYRPPKRYRHPQIDQALTKHRTLNESRLLAKLYLIPGLCVPQLIACDPYNGFIWLEFLGEDLPGGHGFSNLKNFLWMHDQDPYSDLVATTLRKVGRQIGLLHWNDYCHGDLTSSNIVLVRDGARWTPHLIDFGLGSVSNLVEDKGVDLYVLERAILSTHSKHAEKYNAWIMEGFEEVYREQGAKGAKKLKEVTKRFEEVRLRGRKRSMLG
What is the function of this protein?
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.  BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1.  The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation.  The complex is required for efficient recruitment of transcriptional coactivators.  Important for bud site selection.
What are the official names of this protein?
EKC/KEOPS complex subunit BUD32, Atypical serine/threonine protein kinase BUD32, Bud site selection protein 32, Low-dye-binding protein 14, piD261.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. BUD32 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Chromosome, telomere.
Protein: DEOC_HAEI8
Sequence: MTSNQLAQYIDHTALTAEKNEQDISTLCNEAIEHGFYSVCINSGYIPLAKEKLAGSNVKICTVVGFPLGANLTSVKAFETQEAIKAGANEIDMVINVGWIKSQKWDAVKQDIQAVFNACNGTPLKVILETCLLTKDEIVKACEICKEIGVAFVKTSTGFNKGGATVEDVALMKQTVGNIGVKASGGVRDTETALAMIKAGATRIGASAGIAIISGTQDTQSTY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD2_LACJO
Sequence: MKKLLEGKTPANEIKENLIEEIKKLKSDGINPTLCVIEVGDDPASKIYLRVKRNLAKKVGIKEIGLHFPANTSQAELLEKIEDLNQDPSINGIMVQLPVPPQIDPRAIFETIAPEKDADGFSPLNLGRLWEGQSDVIPATVRSILTLIDYYGIEMAGKNTVIIGRSVIVGKPLAAVLVERDATVTIAHSKTKNLSELTKNADVIISDVGKAHLVTEDMVKEGAVIIDVGMNRENGKLMGDVDFDMVAPKAKAITPVPGGVGPLTVASLMKQAVILTRKQHGR
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD 2.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: RL10_CAMFF
Sequence: MTRNEKAEIISNLEAEFKTSDAIVVCDYKGLSVKKLEALRNSARELNVKVQVVKNTLANIALNNCGKSGMELKDTNIFVWGEDQLAVTKVVAKFEESNNELFKIKTAHIDGEVASVSKVVALSKMPSRDELIAMLLQVWNAPIQNFTIGLNALREKKEQTA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: CH60_OLEA2
Sequence: MASKEIVFDTKARERLARGVDKLANAVKVTLGPKGRNVVIEKSFGAPVITKDGVSVAKEIELEDKFENMGAQMVKEVASKTSDIAGDGTTTATILAQAIYKEGVKLVAAGRNPMAIKRGVDKAVEALVKELGNLAKPTRDQKEIAQVGTISANSDTTIGNIIAEAMSKVGKEGVITVEEAKGLETTLEVVEGMQFDRGYLSPYFVTDPEKMVCEMDEPLILINEKKISSMKDMLPVLEQVAKMNRPLVIIAEDVDGEALATLVVNKLRGTLQVVAVKAPGFGERRKAMLEDIATLTGGRVISEEMGIKLENATVADLGNAKRIVVDKENTTIVDGAGESEAIKARVKMIRAQIEETSSDYDREKLQERLAKIVGGVAVINVGAATETEMKEKKDRVEDALNATRAAVEEGIVPGGGTALVRCCKVLDDVKPADDDEAAGVTIIRRAIEEPLRQIAANAGFEGSIICEKVKEGKDAFGFNAATGEFEDLIAAGVIDPKKVSRIALQNAASVASLLLTTECAIAEKPKEDAPAAPAMGGMGGMGGMGGMY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OR2A4_HUMAN
Sequence: MGDNITSIREFLLLGFPVGPRIQMLLFGLFSLFYVFTLLGNGTILGLISLDSRLHAPMYFFLSHLAVVDIAYACNTVPRMLVNLLHPAKPISFAGRMMQTFLFSTFAVTECLLLVVMSYDLYVAICHPLRYLAIMTWRVCITLAVTSWTTGVLLSLIHLVLLLPLPFCRPQKIYHFFCEILAVLKLACADTHINENMVLAGAISGLVGPLSTIVVSYMCILCAILQIQSREVQRKAFRTCFSHLCVIGLVYGTAIIMYVGPRYGNPKEQKKYLLLFHSLFNPMLNPLICSLRNSEVKNTLKRVLGVERAL
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 2A4, Olfactory receptor 2A10, Olfactory receptor OR6-37.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TAL_YERE8
Sequence: MTDKLTSLRQITTVVADTGDIAAMKLYQPQDATTNPSLILNAAQIPEYRKLIDEAIAWAREQSSDHAQQIVDATDKLAVNIGLEILKLIPGRISTEVDARLSYDTVASVAKAKRLIKLYNEAGISNDRILIKLASTWQGIRAAEQLEKEGINCNLTLLFSFAQARACAEAGVFLISPFVGRILDWYKANGDKKEFAPHEDPGVVSVTEIYQYYKKHGYKTVVMGASFRNLGEIIELAGCDRLTIAPSLLKELAESEGPVERKLAYTGEVQAKPTPLTEAEFYWQHNQDPMAIDKLADGIRKFAIDQGKLEKMISDLL
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLO_THET8
Sequence: MGRILRGLAGEGDLRVVAAETTDVVEEARLRHGLSPTATAALGRAMTGALLLAQLLLKTPKERITLRVEGTGPLGGLVVEADAFGHVRGYVKNPRAEVPLREDGKLNVGELVGAGALRVDRSLPSGEVYTSTVPLVSGEIAEDLAHYLWQSEQIPSAVLLGVRVKGEGEVEVAGGVAVQVMPGAREEVLDRLEANLKDLPGLTPLLRERGLEGALEALLAGLGFERTDLRALGYFQNEIPARFRCRCNREKALEALVFFTPEEREDMIVKDGGAEVVCHWCGEVYRFSPEEVRSLVAEVRCPDCGTLWLYPKGDGTLARIEGETCRCGRKVELPSETRPQA
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLX4_KOMPG
Sequence: MEFVSTQIQSAYEDYEEKERHDRDIKKKLASFKSAEFGHNFAEQTSQNSNPRKRKISEKSQKERPIRSLNAQVLNMFHGNVELIKQQRALLKVLSGKKRKVNEVLKHVENIELENSTTHRDKRKIAGTRINSSTFPDDFGEVLYTKNEWDLLINSIRIRFPRLSATSRKTLNMITEKYNERLHSAEVSIWDASSMPPIQLTSDDIRVLHDLKEDDETEPNELESISDTRSVILTLSQALKQDTSKIVEEEQNIEEVEGGMPLSQGVEDVPDSEPEVLAKNERSIISLNSDMIVQSSQVEPIILSSDAGTPQRRRDSSQLTQPLEEPILTTHLKSSPALSKHSKTPTSTQSPIKLPFNFRESTPAIDQLPSFLDDWRGAVVSDESQEVVYSTAQNHSQTKSSAYSTARSNFEDNSTRKTLNTGENEDSITVLKKTIVPFYGKINPEKEIVYHSIEENEEGETREIKSKLMDRMRLPNNEEINVIPDSESDSEHDVSFLEVISVVKRREPELEGDFSGFNTNLFNPPRQDTLISLDENDSEEVFRSQSQNYIQLNNTQDQTQDPTSKQREPTNTQLEPDNEVVNDEETFEKWKLLLKSNPEIYQQIVTFKPLFLSEIIKFLEANGFLMPKPKDVNLLKRFLDTQSVCFTERARK
What is the function of this protein?
Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination.  Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA (By similarity).
What are the official names of this protein?
Structure-specific endonuclease subunit SLX4.
What is the protein family that this protein belongs to?
Belongs to the SLX4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NSRP1_HUMAN
Sequence: MAIPGRQYGLILPKKTQQLHPVLQKPSVFGNDSDDDDETSVSESLQREAAKKQAMKQTKLEIQKALAEDATVYEYDSIYDEMQKKKEENNPKLLLGKDRKPKYIHNLLKAVEIRKKEQEKRMEKKIQREREMEKGEFDDKEAFVTSAYKKKLQERAEEEEREKRAAALEACLDVTKQKDLSGFYRHLLNQAVGEEEVPKCSFREARSGIKEEKSRGFSNEVSSKNRIPQEKCILQTDVKVEENPDADSDFDAKSSADDEIEETRVNCRREKVIETPENDFKHHRSQNHSRSPSEERGHSTRHHTKGSRTSRGHEKREDQHQQKQSRDQENHYTDRDYRKERDSHRHREASHRDSHWKRHEQEDKPRARDQRERSDRVWKREKDREKYSQREQERDRQQNDQNRPSEKGEKEEKSKAKEEHMKVRKERYENNDKYRDREKREVGVQSSERNQDRKESSPNSRAKDKFLDQERSNKMRNMAKDKERNQEKPSNSESSLGAKHRLTEEGQEKGKEQERPPEAVSKFAKRNNEETVMSARDRYLARQMARVNAKTYIEKEDD
What is the function of this protein?
RNA-binding protein that mediates pre-mRNA alternative splicing regulation.
What are the official names of this protein?
Nuclear speckle splicing regulatory protein 1, Coiled-coil domain-containing protein 55, Nuclear speckle-related protein 70, NSrp70.
What is the protein family that this protein belongs to?
Belongs to the NSRP1 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Note=Colocalizes with splicing factors SRSF1 and SRSF2 in speckles.
Protein: RL15_BACCQ
Sequence: MKLHELKPAEGSRKVRNRVGRGIGSGNGKTAGKGHKGQNARSGGGVRLGFEGGQTPLFRRLPKRGFTNINRKEFAIVNLSTLNRFEDGTEVTPELLLETGVISKLNDGVKILASGAVEKKLTVKAHKFSSSAKEAIEAAGGSVEVI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: IL5_PIG
Sequence: MRMLLHLSLLGLGAAYVSAIAVENTMNRLVAETLTLLSIHRTLLIGDGNLMISTPVHTNHQLCIEEVFQGIDTLKNQTARGDAVEKLFQNLSLIKEYIDRQKKNCGGERWRVTQFLDYLQVFLGVINTEWTMES
What is the function of this protein?
Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils.  Acts also on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation (By similarity).  Mechanistically, exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB.  Binding to the receptor leads to activation of various kinases including LYN, SYK and JAK2 and thereby propagates signals through the RAS-MAPK and JAK-STAT5 pathways respectively (By similarity).
What are the official names of this protein?
Interleukin-5, IL-5, Eosinophil differentiation factor, T-cell replacing factor, TRF.
What is the protein family that this protein belongs to?
Belongs to the IL-5 family.
What are the subcellular locations of this protein?
Secreted.
Protein: DM7A_DROYA
Sequence: MLQVQAVHRDEKQAVKLKKTTYLPYLFNLVLPKMFYPNRIVVARLYTDVHEHDKQAAEYFEGFQTPCFEVPASLFPGEAPLDKIVFMPTVMLPMGFEAGGVFGPGVLPRRSYPIDLMASGHKGQTPPLFVGLRSLYVQLPSGIESFLDTVVDNAAGQDALVYGSCQPGNHPSKGEQSKELMHSNDCSLSIAYNLPAPPTPPSPYPFPPLPVQYNIYTPDLSNVHMLMLQQRNPTVALLSTVNHPHVPAVAFATMGDEECPKFELPSDIFPICEGVNRPIFLPRRFLPKGFDAGCVFKPASLPKLWFVKHIGGFNRPQPQHNNAITPPLFVGKISLVVGAHHLAKELQRQGEQKAQSEGAEGGSLKVVEPNGGFIPVTQGFMVMETEQQTPPRGAYSLESYQEASEKGCVVRAIKDEAIEATDTLLSKLASKPEDMQKKYLSCFKVDSDIDLMAEAMADMGTAEMSLLAKRETLPGVDGPRALDQLRQVVEDRSQIRSHTDQLIQDHIYRMDRNRMLALRQPFAPWFGCGTIERK
What are the official names of this protein?
DM7 family protein GE17491.
What is the protein family that this protein belongs to?
Belongs to the DM7 family.
Protein: GLSA_CLOBH
Sequence: MNRLLKTIIENNRKWISEGKVASYIPELSKMDKNLLGISVCTLGGEEYWEGDAEVKFTIQSISKIVTLMLAIIDNGEDYVFSKVGMEPTETAFNSIVNLEAKESHKPINPMINAGAIVVASMVAGKDSDEKFDRILKFTRKISGNNDIDINLNVYESEKETGHRNRALAYFMKSTGALKGNVEEILDVYFKQCSIEITCKDLARIGVMLANDGVSPYTGDRIVPRHVARIVKTIMVTCGMYDASGNFAVHIGIPAKSGVGGGIIACAPRRMGIGVLGTALDEKGNSIAGTKILEELSKQLDLSIF
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: PSAJ_AETGR
Sequence: MRDLKTYLSVAPVLSTLWFGSLAGLLIEINRLFPDGLTFPSSY
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX, PSI-J.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: NSP1_ORYSJ
Sequence: MSYHEEERHGGNGLDWFEESMSSLLAADVDLAGGGGDAGGGGYAWWWAASPAAQQDDIGSVVAQTLSPPSTAAPAAASPSIASPAASSPSDVPSSSSKKRKSPAHRAPGHTGGKKGGGGKGGGGGSDRDMRWAEQLLNPCAVAVEAGNLSRVQHLFYVLGELESFSGDANHRLAAHGLRALARWLPAAVGPAAAAAVRVPPCSERPTTAFAAAEPRLFRASLIRFHEVSPWFALPNALANAAIAQASTCGAAGATPRPLHVVDLGVSHGVQWPTLLESLTRQPGGRAPPSVRLTVVGPGATATSPVAPFSASPPGYDFSPHLLRYAKSINLDLRISRAATLDDAVPGDDGEALVVCLQFRLGHAAAEERREVLRKARGLNPELVVLSELDSGVGVVGGDGGSAAGEFAARLELLWRFLESTSAAFKGKDVEERRLLEAEAGAILAAADVAAAGEGREGWRERMAAAGFEEAPFGAEAVESARSLLRKYDSGWEMSAPSPAAAAVALRWKGQPVSFCSLWRPAA
What is the function of this protein?
Transcription factor involved in the control of strigolactone biosynthesis in roots through the activation of the beta-carotene isomerase D27, which participates in a pathway leading to biosynthesis of strigolactones.
What are the official names of this protein?
Protein NODULATION SIGNALING PATHWAY 1, OsNSP1, GRAS family protein 14, OsGRAS-14.
What is the protein family that this protein belongs to?
Belongs to the GRAS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: BCAS1_MOUSE
Sequence: MGNQMSVPLRPGDQEHDPGADTCKVTSDNECVQNGNPVVLSTRVIQHYEEVDLGISSSKDNVATSSPKTMEAQAVGDASGKNLGKEAKTKAPAARSHFFLTLSRPVPGRPGDQGTDSSAASGRFDVSPSAAPENKDPSEHGALPVAAAPGQAPDKTPGCPEAKQQTLPATGPLAPSPPESQAEAPAQDKDFGFLNRFFKLDKGRESAPVNSQPKEAKGSEDPEQATEAPAVPGNPHGVSAGEDIVDSEQRGQDVDTLSYSVPGDPEVPGTTKEDPQVVDTTENSSSIMSFFKTLVSPNKTETKKDPEDTKATKADSVCDGHAAGQKMSETQAKSKKKRLDSPRLGLSFRKLFRHKDTENSPTTSANLKSDKANFTPQETRGKTKATKSCSPPPPPPEPTSEGRDSGKEKAGPTSLPLGKLFWKKSVKEDTLSTGAEENAVCESPVETVRLEEVESSLQTVDLSEETQPEPTDVKVKEESKPRKTPLMAFLRQMSVRSSEGIPRSEESNVKDSSCQTSNSVEKTPSPPEPEPAGTAQKNKETSSSKDKKSVDKKSATENSKQKNGKQEVREPAPCVQPPTVEANAMQTGDKTPKKSEKRRQSLGGFLKGLGPKRMSDAQVQTDPVSIGPVGKSK
What is the function of this protein?
Required for myelination.
What are the official names of this protein?
Breast carcinoma-amplified sequence 1 homolog, Novel amplified in breast cancer 1 homolog.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPY1_SACBS
Sequence: MNLQMIGTGNAFAKKYFNNNALIEQDGFKLLIDCGITAPLALYELGIGMEELDAVLVTHTHGDHVGGLEEYGFQMKFKHGRRPVLLLPEALVDPLWQNTLSGGMTQEGLEKLEDAFDVRALRVGDVQELAPNLCVELVPTSHIAGKKSYSLILNRDVFYSADMTFEPELLTTLVRDRGIRRILHEVQLEGPGAVHTTLDELLSLPEEMQSIIKLMHYADNKEQFVGRTGKMEFLEQGLVYPI
What is the function of this protein?
Counteracts the endogenous Pycsar antiviral defense system.  Phosphodiesterase that enables metal-dependent hydrolysis of host cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
What are the official names of this protein?
Anti-Pycsar protein Apyc1, Apyc1.
What is the protein family that this protein belongs to?
Belongs to the anti-Pycsar protein Apyc1 family.
Protein: ENO_BURP0
Sequence: MSAIVDIIGREILDSRGNPTVECDVLLESGTMGRAAVPSGASTGSREAIELRDGEAGRYGGKGVLKAVEHINTEISEAIMGLDASEQAFLDKTLLELDGTDNKSRLGANAMLAVSMAVAKAAAEEAGLPLYRYFGGSGAMQLPVPMMNIVNGGAHANNSLDIQEFMIVPVSQPTFREALRCGAEVFHALKKILGDRGMSTAVGDEGGFAPNFGSNDECLSTILQAIEKAGYRAGEDVLLALDCAASEFYHDGKYQLAGEGLQLSSAEFTDYLATLADKFPIVSIEDGMHEGDWDGWKLLTERLGKKVQLVGDDLFVTNTRILKEGIEKGIANSILIKINQIGTLTETFAAIEMAKRARYTAVISHRSGETEDSTIADIAVGLNAGQIKTGSLSRSDRISKYNQLLRIEEDLGDIASYPGKSAFYNLR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: SMIM7_XENTR
Sequence: MIGDLLLFGTLLVNAGAVLNFKLKKKESQGFGDDLMTEATTGDNIREFLLSLRYFRIFIALWNIFMMFCMIVLFGS
What are the official names of this protein?
Small integral membrane protein 7.
What is the protein family that this protein belongs to?
Belongs to the SMIM7 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: NRM_DROME
Sequence: MTSIAKSIVLLASLATFAYSLYVVGSLMMFLSTPRSISKAHTWIFNLLDNKSRLQTAYGPVVFDTLYLIGFIFQHSFLKSAVVKKLLAKLGLSGAERTIYSLTSSLCLHYLIVNWLPAQSIVLWQIDVEQSAPLWWTFVITHGICWVVIFGGSLVMDLPELLGVKQAYYDLKAYGPPISYKSGELRNLYAHVRHPSFVGLSVILFATNVMSVDRLVMALLLTTYMYLAWSTDQKDVAYQKIQLQRKKLELKAK
What are the official names of this protein?
Nurim homolog, Nuclear envelope membrane protein, Nuclear rim protein.
What is the protein family that this protein belongs to?
Belongs to the nurim family.
What are the subcellular locations of this protein?
Nucleus inner membrane; Multi-pass membrane protein.
Protein: Y456_MYCGE
Sequence: MSDLTKFNKFFLTPNKLNAFLRVIGLCGLFSVIAISFGIYSYTRNEIPNIASLFLIVLGSVVLFLAFVIHFAALFKRNKLLKKVNKENRTNLWQKEMGNFKAIESFEFFEQGPISSDILPSFYPTALYNFEPLPRQFKVTYKDGSEFVFGHIYAIKRSSNKTEKVACLIAITPAINSENHFFLTDANYSLNKNVAQFEALTENKKQENISLFVEKDSNFSFQNLDTEVLNKVLFNPLNVYAKFNVYNDTVHTYLFMSVPTTFMDTKLKVNEAFDDLVTNIKLQASYDFKTLNSMQKVVDLLHNKLIKKPESKSSSQKSVETEIEKEVKDKLAKN
What are the official names of this protein?
Uncharacterized protein MG456.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ZN511_DANRE
Sequence: MLQPEIIEFLASTTPQILAKNIPVTENRESKRHDIQQKAEAGEEKAVSPFEFRPQRLRFAVEDEYFEDGDINRHMYLQNIVTSFVDDKQPPTISEFRCHIAGCKQLFDTLEGYEHHYNALHRNVCSNCKRSFPSNRLLEIHILEWHDSLFQIMAEKQCMYECLVEGCGLKFKTSKERKDHLIRTHSYPADFRFDKSKKIGRTTEKKTQQKKDAHMEVSATVLQQESSESMDFSLTPEPVETEPMQAANLKPRYSYKVPSSICFGQGSVRGFRGRRKK
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 511.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SCN9A_MOUSE
Sequence: MAMLPPPGPQSFVHFTKQSLALIEQRISEEKAKGHKDEKKDDEEEGPKPSSDLEAGKQLPFIYGDIPPGMVSEPLEDLDPYYADKKTFIVLNKGKAIFRFNATPALYMLSPFSPLRRISIKILVHSLFSMLIMCTILTNCIFMTMSNPPDWTKNVEYTFTGIYTFESLIKILARGFCVGEFTFLRDPWNWLDFVVIVFAYLTEFVNLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLKHKCFRKDLEQNETLESIMSTAESEEELKRYFYYLEGSKDALLCGFSTDSGQCPEGYECVTAGRNPDYGYTSFDTFGWAFLALFRLMTQDYWENLYQQTLRAAGKTYMIFFVVVIFLGSFYLINLILAVVAMAYEEQNQANIEEAKQKELEFQQMLDRLKKEQEEAEAIAAAAAEYTSLGRSRIMGLSESSSETSRLSSKSAKERRNRRKKKKQKLSSGEEKGDDEKLSKSGSEESIRKKSFHLGVEGHHRAREKRLSTPNQSPLSIRGSLFSARRSSRTSLFSFKGRGRDLGSETEFADDEHSIFGDNESRRGSLFVPHRPRERRSSNISQASRSPPVLPVNGKMHSAVDCNGVVSLVDGPSALMLPNGQLLPEVIIDKATSDDSGTTNQMRKKRLSSSYFLSEDMLNDPHLRQRAMSRASILTNTVEELEESRQKCPPWWYRFAHTFLIWNCSPYWIKFKKFIYFIVMDPFVDLAITICIVLNTLFMAMEHHPMTDEFKNVLAVGNLVFTGIFAAEMVLKLIAMDPYEYFQVGWNIFDSLIVTLSLVELFLADVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECVCKINENCKLPRWHMNDFFHSFLIVFRVLCGEWIETMWDCMEVAGQTMCLIVYMMVMVIGNLVVLNLFLALLLSSFSSDNLTAIEEDTDANNLQIAVARIKRGINYVKQTLREFILKSFSKKPKGSKDTKRTADPNNKRENYISNRTLAEISKDHNFLKEKDKISGFSSSLDKSFMDENDYQSFIHNPSLTVTVPIAPGESDLENMNTEELSSDSDSDYSKERRNRSSSSECSTVDNPLPGEEEAEAEPINADEPEACFTDGCVRRFPCCQVNIDSGKGKVWWTIRKTCYRIVEHSWFESFIVLMILLSSGALAFEDIYIEKKKTIKIILEYADKIFTYIFILEMLLKWVAYGYKTYFTNAWCWLDFLIVDVSLVTLVANTLGYSDLGPIKSLRTLRALRPLRALSRFEGMRVVVNALIGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYECVNTTDGSRFSVSQVANRSECFALMNVSGNVRWKNLKVNFDNVGLGYLSLLQVATFKGWMDIMYAAVDSVNVNAQPIYEYNLYMYIYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKLGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPGNKFQGCIFDLVTNQAFDITIMVLICLNMVTMMVEKEGQTDYMSFVLYWINVVFIILFTGECVLKLISLRHYYFTVGWNIFDFVVVILSIVGMFLAEMIEKYFVSPTLFRVIRLARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKKEAGINDMFNFETFGNSMICLFQITTSAGWDGLLAPILNSAPPDCDPKKVHPGSSVEGDCGNPSVGIFYFVSYIIISFLVVVNMYIAVILENFSVATEESTEPLSEDDFEMFYEVWEKFDPDATQFIEFCKLSDFAAALDPPLLIAKPNKVQLIAMDLPMVSGDRIHCLDILFAFTKRVLGESGEMDSLRSQMEERFMSANPSKVSYEPITTTLKRKQEDVSATIIQRAYRRYRLRQNVKNISSIYIKDGDRDDDLPNKEDIVFDNVNENSSPEKTDATASTISPPSYDSVTKPDQEKYETDKTEKEDKEKDESRK
What is the function of this protein?
Mediates the voltage-dependent sodium ion permeability of excitable membranes.  Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient (PubMed:15123669).  It is a tetrodotoxin-sensitive Na(+) channel isoform.  Plays a role in pain mechanisms, especially in the development of inflammatory pain (PubMed:15314237).
What are the official names of this protein?
Sodium channel protein type 9 subunit alpha, Peripheral sodium channel 1, PN1, Sodium channel protein type IX subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.7.
What is the protein family that this protein belongs to?
Belongs to the sodium channel (TC 1.A.1.10) family. Nav1.7/SCN9A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell projection, neuron projection. Note=In neurite terminals.
Protein: SER3_DROME
Sequence: MRGLTLLSLAFLGVCSALTVPHSLVHPRDLEIRHGGIEGRITNGNLASEGQVPYIVGVSLNSNGNWWWCGGSIIGHTWVLTAAHCTAGADEASLYYGAVNYNEPAFRHTVSSENFIRYPHYVGLDHDLALIKTPHVDFYSLVNKIELPSLDDRYNSYENNWVQAAGWGAIYDGSNVVEDLRVVDLKVISVAECQAYYGTDTASENTICVETPDGKATCQGDSGGPLVTKEGDKLIGITSFVSAYGCQVGGPAGFTRVTKYLEWIKEETGIYY
What is the function of this protein?
Its major function may be to aid in digestion.
What are the official names of this protein?
Serine protease 3, Protein Jonah 99Ci.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.