PharMolix/UniProtQA huggingface dataset:
Protein: REB1_SCHPO
Sequence: MDTSVLNPELQIHGFIGVDSLQSSRKRKNDFDDFPLNKGLKTNNNDYSGSIEPKFSPALSIKEDGKNDRNFEALMSLQAQDSNLSEQNTSIHLDALASSSIALGNDNVDSSAFLSKVNKGVNAMRNSTSNQTNDSILISPSEITNMDPFLKGSARWTAEHWDYLERRMQNFCQTYSLDHTQVADSLHEKRLHGPLSSLVKLLVQEMPSFTRRTILRHLRALYNIPGYEKYSRKNSSGRGDFGVQETAIISQEVHNFIMDQGWSEYQFCNQIWAGKCPKTIRMFYSNLYKKLSHRDAKSIYHHVRRAYNPFEDRCVWSKEEDEELRKNVVEHGKCWTKIGRKMARMPNDCRDRWRDVVRFGDKLKRNAWSLEEETQLLQIVAELRNREDLSSDINWTLVAQMLGTRTRLQCRYKFQQLTKAASKFELQENVWLLERIYDSLLNNGGKIHWENIVKEANGRWTRDQMLFQFINLKKMIPSYDNLPLLEATKSAIDDFKVVLSGFSN
What is the function of this protein?
DNA-binding protein that recognizes sites within both the enhancer and the promoter of rRNA transcription, as well as upstream of many genes transcribed by RNA polymerase II.  Has a role in the termination of RNA polymerase I catalyzed transcription.
What are the official names of this protein?
DNA-binding protein reb1.
What are the subcellular locations of this protein?
Nucleus.
Protein: P2C30_ARATH
Sequence: MQLSKNPIKQTRNREKNYTDDFTMKRSVIMAPESPVFFPPPLVFSPTSVKTPLSSPRSSPPKLTMVACPPRKPKETKTTGSDSETVLKRKRPPMLDLTAAPTVASWCSTTRETAEKGAEVVEAEEDGYYSVYCKRGRRGPMEDRYFAAVDRNDDGGYKNAFFGVFDGHGGSKAAEFAAMNLGNNIEAAMASARSGEDGCSMESAIREGYIKTDEDFLKEGSRGGACCVTALISKGELAVSNAGDCRAVMSRGGTAEALTSDHNPSQANELKRIEALGGYVDCCNGVWRIQGTLAVSRGIGDRYLKEWVIAEPETRTLRIKPEFEFLILASDGLWDKVTNQEAVDVVRPYCVGVENPMTLSACKKLAELSVKRGSLDDISLIIIQLQNFLP
What are the official names of this protein?
Probable protein phosphatase 2C 30, AtPP2C30, AthPP2C5.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: HIS4_OPITP
Sequence: MTIYPAIDIKGGRCVRLTQGRAEQETIYAQNPADVAMQFRAAGSEWVHVVDLDGAFAGEPQNLAAVQAIVAVGMKVQFGGGLRTRAAVERALALGVSRVVLGTRAAESESFVGELVQAFGDKIAVGIDAKNGKVAVKGWVATADLSTLVLARRMDTLGVATLIHTDIGTDGMLTGPNLAAQEALCSAVKSRVIASGGVSRRDDVVNLAKLAQRHANLDGVIVGKALYERRVELADLLSLAAAS
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPVL_DICDI
Sequence: MKVSLSFLLTILIVIITIKVNLSQEIKISPFFANNLKFEPIPDYIEYDSDSDAGEALFLSNYLDDHKTAKQKSCVDIGAPFQSCDKLLEIDSNLRDTEDFFTFTGFITVNETYNSNTFFWFLESQNGDKNSPLVIFLQGGPGGASTFSLFVETGPYELLDNFTLVQREITWNSEFAMLYIDNPVGTGFSFTDSQEGYSNNEDEIATNLYTFLQQFYKLYPEYYTNELYITGESYAGKYIPAFSYHIIQQNQNSNNPNINLKGIAIGDGLCDPITQVTQYANLAFYTGLADLQQQEVMFEYQDKIVEAINQEQWSVANDLFTDLINGPPDYFQNITGESDYYDIRKTVEPTYGGDFTAFLNQSSIRAMIHVGNNYFQNNNDVYIHLEQDIPKSVKQLFPTILDNIKVILYNGQFDFIVGPSLTETMIRTIEWEGIQPFLESPKIIWKIPSDNVDVAGFVRQWNSFTQVVVRQAGHMVPLDQPARAFDMIDRFINNEPFPSG
What is the function of this protein?
May be involved in the digestion of phagocytosed particles in the lysosome, participation in an inflammatory protease cascade, and trimming of peptides for antigen presentation.
What are the official names of this protein?
Probable serine carboxypeptidase CPVL.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Secreted.
Protein: AMPR_ENTCL
Sequence: MTRSYLPLNSLRAFEAAARHLSFTHAAIELNVTHSAISQHVKTLEQHLNCQLFVRVSRGLMLTTEGENLLPVLNDSFDRIAGMLDRFANHRAQEKLKIGVVGTFATGVLFSQLEDFRRGYPHIDLQLSTHNNRVDPAAEGLDYTIRYGGGAWHGTEAEFLCHAPLAPLCTPDIAASLHSPADILRFTLLRSYRRDEWTAWMQAAGEHPPSPTHRVMVFDSSVTMLEAAQAGVGIAIAPVDMFTHLLASERIVQPFATQIELGSYWLTRLQSRAETPAMREFSRWLVEKMKK
What is the function of this protein?
This protein is a positive regulator of gene expression of cephalosporinase (AmpC).
What are the official names of this protein?
HTH-type transcriptional activator AmpR.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA1_TRIL1
Sequence: MKPRVLVIAGPTASGKSALALDLAVALDGEIICADSLTVYRGLDIGSAKPTAEQQRQIPHHLLDIREPTEPFTAADFKLAAKAAIAAICQRGKRPILAGGTGLYLRALLRGLNDAPGEDPVLRETLRKRLECEGAETLLAELAKVDPDTSQRLHPNNRNRIIRALEVFQTTGIPLSQFQAEHGFADSPYDSLQFCLDLPRPELYQRIDDRVDAMLAAGLVAEVQGLLQSGVPADCKPLQAIGYKEVLAHLQGEYDHNEMVRLIKRNTRHFAKRQLTWFRSEPAMQWVAYPENSATIHSAAATFFA
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase 1, Dimethylallyl diphosphate:tRNA dimethylallyltransferase 1, DMAPP:tRNA dimethylallyltransferase 1, DMATase 1, Isopentenyl-diphosphate:tRNA isopentenyltransferase 1, IPP transferase 1, IPPT 1, IPTase 1.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: HEMT2_HEDDI
Sequence: MGFEIPEPYKWDESFQVFYEKLDEEHKQIFNAIFALCGGNNADNLKSLVDVTANHFADEEAMMKASGSYGDFDSHKKKHEDFLAVIRGLGAPVPQDKINYAKEWLVNHIKGTDFGYKGKL
What is the function of this protein?
May act as a buffer to control the concentration and therefore the toxicity of cadmium.  Also involved in defence towards bacteria growth by acting as an iron scavenger.
What are the official names of this protein?
Hemerythrin, MP II, MPII, Non-metallothionein cadmium-binding protein, CD-BP.
What is the protein family that this protein belongs to?
Belongs to the hemerythrin family.
Protein: QUEF_FRACC
Sequence: MALTKLGNPEAKADRSLETFPIDDTSQEIRIDCREFTCRCPITGQPDWATIRIDYRPGGRGLETKSLKLYLETFREEGIFHEHLATLIRDDLVAALAPVQLTVTVNFNARGGIALAASSTYRREA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTND_DICDI
Sequence: MKSYFYDNESDVISLDYLKEHNVLYFPMDREKENYKEPLETLCKERGYKNRDEVKLSKETPGLEDKLKIFFEEHLHDDEEIRFILDGCGFFDIRDKNDKWVKIKEKKGDLIIVPANMYHRFALDESRNIHAMRLFTDAPKWVPINRY
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SYGA_SALTI
Sequence: MQKFDTRTFQGLILTLQDYWARQGCTIVQPLDMEVGAGTSHPMTCLRALGPEPMATAYVQPSRRPTDGRYGENPNRLQHYYQFQVVIKPSPENIQELYLGSLKELGMDPTIHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECKLVTGEITYGLERLAMYIQGVDSVYDLVWSDGPLGKTTYGDVFHQNEVEQSTYNFEYADVDFLFTCFEQYEKEAQQLLALENPLPLPAYERILKAAHSFNLLDARKAISVTERQRYILRIRTLTKAVAEAYYASREALGFPMCNKDK
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LYOX_BOVIN
Sequence: MRFAWTALLGSLQLCALVRCAPPAASHRQPPREQAAAPGAWRQKIQWENNGQVFSLLSLGSQYQPQRRRDPGATAPGAANATAPQMRTPILLLRNNRTAAARVRTAGPSAAAAGRPRPAARHWFQAGYSTSGAHDAGTSRADNQTAPGEVPTLSNLRPPNRVEVDGMVGDDPYNPYKYTDDNPYYNYYDTYERPRPGSRYRPGYGTGYFQYGLPDLVPDPYYIQASTYVQKMAMYNLRCAAEENCLASSAYRXDVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDASTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCYDTYNADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYSNNVVRCEIRYTGHHAYASGCTISPY
What is the function of this protein?
Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin.  Regulator of Ras expression.  May play a role in tumor suppression.  Plays a role in the aortic wall architecture (By similarity).
What are the official names of this protein?
Protein-lysine 6-oxidase, Lysyl oxidase.
What is the protein family that this protein belongs to?
Belongs to the lysyl oxidase family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space.
Protein: YEDM_ECOLI
Sequence: MFPLNDLSLKTQPVQLNKVTSNTESTIKQHELVSDDAIINELSSELVSCLGNGKFTPISEDSKLFNMLSEFKLLHSEYFEWGDYSLWFQDFSIYNKIGFIMIEKIRELVTHPFGIN
What are the official names of this protein?
Uncharacterized protein YedM.
Protein: GNGF_SALTI
Sequence: MRNRTLADLDRVVALGGGHGLGRVLSSLSSLGSRLTGIVTTTDNGGSTGRIRRSEGGIAWGDMRNCLNQLITEPSVASAMFEYRFGGNGELSGHNLGNLMLKALDHLSVRPLEAINLIRNLLKVDAQLIPMSELPVDLMAIDDQGHEIYGEVNIDQLATPPQEIMLTPNVPATREAVQAINDADLILIGPGSFYTSLMPCLLLDELAQALRRTPAPMVYIGNLGRELSLPAASLTLVDKLAMMEQYIGKKVIDTVVVGPRVDVSAVNDRLVIQEVLEASDIPYRHDRQLLHNALEKALQALG
What is the function of this protein?
Required for morphogenesis under gluconeogenic growth conditions.
What are the official names of this protein?
Putative gluconeogenesis factor.
What is the protein family that this protein belongs to?
Belongs to the gluconeogenesis factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTCA_VIBC1
Sequence: MNQVDTRKETLEFNKLQKRLRRNVGNAITDYNMIEEGDVVMACISGGKDSFAMLDILLNLQKAAPIKFEVVAVNLDQKQPGFPEHILPDYFETLNIPYYIVDKDTYSVVKEKVPEGKTTCGLCSRLRRGTLYSFAEKIGATKLALGHHMDDIVETMFLNMFHGSRLKAMPPKLRSDDGRNVVIRPLTYCREKDLIKYAEHKEFPIIPCNLCGSQENLQRQSIKAMLIDWDKKTPGRVEAIFKSIQNVSPSQLADRELFDFENLPLDREGNREEYEFSEAVVSSTNIDESMFIDVTNI
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRSF2_PANTR
Sequence: MSYGRPPPDVEGMTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMDAMDGAVLDGRELRVQMARYGRPPDSHHSRRGPPPRRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSRSRSRSRSRSPPPVSKREPKSRSRSKSPPESPEEEGAVSS
What is the function of this protein?
Necessary for the splicing of pre-mRNA.  It is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly.  It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA.  Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF.  Binds to purine-rich RNA sequences, either 5'-AGSAGAGTA-3' (S=C or G) or 5'-GTTCGAGTA-3'.  Can bind to beta-globin mRNA and commit it to the splicing pathway.  The phosphorylated form (by SRPK2) is required for cellular apoptosis in response to cisplatin treatment (By similarity).
What are the official names of this protein?
Serine/arginine-rich splicing factor 2, Splicing component, 35 kDa, Splicing factor SC35, SC-35, Splicing factor, arginine/serine-rich 2.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleoplasm. Nucleus speckle. Note=Phosphorylation by SRPK2 provokes its redistribution from the nuclear speckle to nucleoplasm.
Protein: AB3A_ARATH
Sequence: MADSGPASFWTRANAILRKNLTYQKRNIWSNVRLIMIPFYLCIVLVFIQALFDSQVNNSLDNQCGCQCIDKLGDGKCQMTCGLEYSTRDQGFFCAIPKPQPWPPLILIPRPEYRALDANFTNDSCRRKNSCPVTILFTGNNHSLGAVLSRNLLRRPFAMNSSDLLFSLANNVLATTFKGSATNYLDAGIVSDGSIYNIQPRCPPNSNFSISIGQSPLNFTKDMRCVQGLNLWRNNSIEVNLELFEGYHKGNSDGMINEIVAAYDLFDTNMTNFNVNIWFNATYKDEARNQPYKVVRVPRLVNWVSNAYLQYLQGPRTKMLFEFVKEMPKPETKLRLDIASLIGPIFFTWVILLLLPVILNSLVYEKQQRLRIIMKMHGLGDGPYWIISYAYFLALSTFYIIFLMIFGSVIGLKFFLLNDFSLQFSFYFVYINLQISIAFLLSSAFSKVETASVAAYLYVFGSGLLGMFLFQFLLEGLSFPRRWIFVMELYPGFSLYRGLYEFSQNAYQGNLNGKDGMKWKYFSDNAIDEVFYIIIVEWFVALIATYYIDKMSSSGKDLLFFLKNQNPFKISHSLQKQVSAISVEMEKLDVIHESEKVAQLMLESSTSHAIVCDKLRKVYPGRDGNPPKKAVRVLSLAVPSGECFGMLGPNGAGKTSFINMMTGLVKPTSGAAFVQGLDICKDMDRVYTSMGVCPQHDLLWETLTGREHLLFYGRLKNLKGVDLNQAVEESLRSVNLFHGGVADKPAGKYSGGMKRRLSVAISLIGNPKVVYMDEPSTGLDPASRKNLWTVIKNAKRHTAIILTTHSMEEAEFLCDRLGIFVDGRLQCIGNPKELKGRYGGSYVLTMTTSSEHEKDVEMLVQEVSPNVKKIYHIAGTQKFEIPKDEVRISEVFQVVEKAKSNFKVFAWGLADTTLEDVFIKVARTAQAFNVFS
What are the official names of this protein?
ABC transporter A family member 3, ABC transporter ABCA.3, AtABCA3, ABC2 homolog 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCA family. CPR flippase (TC 3.A.1.211) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: UBS3B_HUMAN
Sequence: MAQYGHPSPLGMAAREELYSKVTPRRNRQQRPGTIKHGSALDVLLSMGFPRARAQKALASTGGRSVQAACDWLFSHVGDPFLDDPLPREYVLYLRPTGPLAQKLSDFWQQSKQICGKNKAHNIFPHITLCQFFMCEDSKVDALGEALQTTVSRWKCKFSAPLPLELYTSSNFIGLFVKEDSAEVLKKFAADFAAEAASKTEVHVEPHKKQLHVTLAYHFQASHLPTLEKLAQNIDVKLGCDWVATIFSRDIRFANHETLQVIYPYTPQNDDELELVPGDFIFMSPMEQTSTSEGWIYGTSLTTGCSGLLPENYITKADECSTWIFHGSYSILNTSSSNSLTFGDGVLERRPYEDQGLGETTPLTIICQPMQPLRVNSQPGPQKRCLFVCRHGERMDVVFGKYWLSQCFDAKGRYIRTNLNMPHSLPQRSGGFRDYEKDAPITVFGCMQARLVGEALLESNTIIDHVYCSPSLRCVQTAHNILKGLQQENHLKIRVEPGLFEWTKWVAGSTLPAWIPPSELAAANLSVDTTYRPHIPISKLVVSESYDTYISRSFQVTKEIISECKSKGNNILIVAHASSLEACTCQLQGLSPQNSKDFVQMVRKIPYLGFCSCEELGETGIWQLTDPPILPLTHGPTGGFNWRETLLQE
What is the function of this protein?
Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases.  Promotes accumulation of activated target receptors, such as T-cell receptors and EGFR, on the cell surface.  Exhibits tyrosine phosphatase activity toward several substrates including EGFR, FAK, SYK, and ZAP70.  Down-regulates proteins that are dually modified by both protein tyrosine phosphorylation and ubiquitination.
What are the official names of this protein?
Ubiquitin-associated and SH3 domain-containing protein B, Cbl-interacting protein p70, Suppressor of T-cell receptor signaling 1, STS-1, T-cell ubiquitin ligand 2, TULA-2, Tyrosine-protein phosphatase STS1/TULA2.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MURQ_MICAN
Sequence: MEQWESRGHLLTEQINPNSLNLDQLNPLELVDLFNREDAQTLKAIAMARQELALGISLTSQALAKGGRLFYIGAGTSGRLGVLDAAECPPTFCTPPELVQGIIAGGAAALVRSSEDLEDKAEDGAAIIAQREIHELDVVVGITAGGTTPYVHGALQAAKQRGATTIAISCVPAEQVEIAVDVDIRLLTGPELLAGSTRLKAGTVTKMALNILSTGTMVMLGKVYGNQMVDVAVTNHKLHDRALRIICHLTDVSREEAAILLEKSGRRVKLALLMQKTGLSAAAGQELLQKHRGQLRAALQAYNQID
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: UH11_RAT
Sequence: QSAREQG
What are the official names of this protein?
Unknown protein from spot P11 of 2D-PAGE of heart tissue.
Protein: SPG4_YEAS7
Sequence: MGSFWDAFAVYDKKKHADPSVYGGNHNNTGDSKTQVMFSKEYRQPRTHQQENLQSMRRSSIGSQDSSDVEDVKEGRLPAEVEIPKNVDISNMSQGEFLRLYESLRRGEPDNKVNR
What is the function of this protein?
Stationary phase-essential protein not required for growth on nonfermentable carbon sources.
What are the official names of this protein?
Stationary phase protein 4.
What is the protein family that this protein belongs to?
Belongs to the SPG4 family.
Protein: GYRB_ACIBA
Sequence: DNSYKVSGGLHGVGVSVVNALSSKLHLTIYRAGQIHEQEYHHGDPQYPLRVIGETDNTGTTVRFWPSAETFSQTIFNVEILARRLRELSFLNAGVRIVLRDERINLEHVYDYEGGLSEFVKYINEGKNHLNEIFHFTADADNGIAVEVALQWNDSYQENVRCFTNNIPQKDGGTHLAGFRAALTRGLNQYLENENILKKEKVNVTGDDAREGLTAIISVKVPDPKFSSQTKEKLVSSEVKPAVEQAMNKEFSAYLLENPQAAKSIAGKIIDAARARDAARKAREMTRRKSALDIAGLPGKLADCQEKDPALSELYLVEGDSAGGSAKQGRNRKMQAILPLKGKILNVERARFDKMISSQEVGTLITALGCGIGREEYNPDKLRYHKII
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERF87_ARATH
Sequence: MEFNGNLNAGSCSRSKKSHRQKQQQPQPQPQQHIEEIKYVGVRRRPWGRYAAEIRNPTTKERYWLGTFDTAEEAALAYDRAARSIRGLTARTNFVYSDMPRGSSVTSFVSPDESQRFISELFNPPSQLEATNSNNNNNNNLYSSTNNQNQNSIEFSYNGWPQEAECGYQSITSNAEHCDHELPPLPPSTCFGAELRIPETDSYWNVAHASIDTFAFELDGFVDQNSLGQSGTEGFNSLPSTFFYQ
What is the function of this protein?
Probably acts as a transcriptional activator.  Binds to the GCC-box pathogenesis-related promoter element.  May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
What are the official names of this protein?
Ethylene-responsive transcription factor ERF087.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: U538_DICDI
Sequence: MENENKILIIRVIRSFEYRTIKNLILKDIDLNTNVSDFKKLVADKIQTTPGFTPFKTKQYDSMKIFFVPHGQKPNNLTINIENDHFFLNNNKSLAENGVVYETEISFFVMEDYLKYKENPENKW
What are the official names of this protein?
UPF0538 protein.
What is the protein family that this protein belongs to?
Belongs to the UPF0538 family.
Protein: SWC4_YEAST
Sequence: MSSSDIFDVLNIKQKSRSPTNGQVSVPSSSAANRPKPQVTGMQRELFNLLGENQPPVVIKSGNNFKEKMLSTSKPSPWSFVEFKANNSVTLRHWVKGSKELIGDTPKESPYSKFNQHLSIPSFTKEEYEAFMNENEGTQKSVESEKNHNENFTNEKKDESKNSWSFEEIEYLFNLCKKYDLRWFLIFDRYSYNNSRTLEDLKEKFYYTCRNYFKASDPSNPLLSSLNFSAEKEIERKKYLQRLLSRSAAEIAEEEALVVESKKFEMAAKRTLAERESLLRLLDSPHSDQTITQYLTSQGMSQLYNALLADKTRKRKHDLNIPENPWMKQQQQFAQHRQLQQLNVKKSEVKENLSPKKTKRQRQEMQTALKRKSESAYAEQLLKDFNSDERKALGVITHGEKLSPGVYLRSTKLSTFKPALQNKILAILQELSLPSRPVMPSFDVMERQEELLKKINTLIDLKKHVDKYEAGMSITK
What is the function of this protein?
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling.  Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A.  The NuA4 complex is also involved in DNA repair.
What are the official names of this protein?
SWR1-complex protein 4, ESA1-associated factor 2.
What is the protein family that this protein belongs to?
Belongs to the SWC4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ADDB_STRP1
Sequence: MKLIYTEMSYSMTEILVNEARKAADQGYRVFYIAPNSLSFEKEREVLTLLPERGTFSIIVTRFVQMSRYFTVESSPSKQHLDDTTLAMIFYRALMQLKPEDLPSYGRLQNNSVFIEQLVELYKELKNAQLSVHDLTGLDHPQKQEDLIKIIELAETIMIQQDYNQDSPLQSFARAIKLGLLNNQLSKTVVVIDGFSRFSAEEDYLLSLLNNNCQEVIIGSYVSQKAYQKSFIKGNIYEASLHFLQDLAQKYHIKPVFATSNQVFKPAFSRLTQLFEATHDFSQVDWQLQKSDLDHFSLWQCHHQKEEIEHVAKSIRQKLYEGYRYKDILVLLGDMDAYQLQIGPIFDKFEIPYYLGKAEPMAAHPLVQFIESLERSQRYNWRREDILNMLKSGLFGCFDDSDIDRFEEYTQFADIKGFTKFSKPFTINSSRQYPLDFLNEMRQDIVLPLQELFKSQKQLGASLVDKLILFLKKIRLAENMQGLAQSQLEVEKNEEVWKRFTDILTSFHHIFGQEKLRLSDCLALIKTGMKSAQYRVVPATLDVVTIKSYDLVQPHSKPFVYAIGLTQSHFPKQIHHSGLLSDQERARINEIRNYRHFDIASAENSKKNHQTALSLFNAATKELVLSVSTVINETFDDLSPYLKELINFGLPLLDKGKNYLSYDNSDIGNYKALLSQIIAINRQDLIEMSDQDKMFWTVVLRYLRKQLRKQQLELPTSDYRLSTKPLSKEVIEVCFPKGIPLKLSATALTVFYNNQYNYFLKYVLNLNKTESIHPDSRIHGQYLHRVFERLMKDHTQEPFDNKLKQAIYHTNQESFFQQVYQDNAEAEYSLAILEDIVRSTAPILQLNQNIQVIDQEKNFQLDMGNEILVHGIIDRIDQLSDGSLGIVDYKSSANQFDIGTFYNGLSPQLMTYLAALKQIAPHDINQLFGAMYLHLQDPKLDLVTFKQIDNTLVESIYKALTYKGIFSEVEKEHLSTGAYQTKNALYSNDELETLLNYNKYLYLKAAKHIKKGHFLINPYTSDGKTVQGDQLKAITRFEADLDMGQARRLVTLPAKEKKECFLTLMRKESHL
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  This subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease RexB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 2 subfamily.
Protein: RS2_CAMHC
Sequence: MVTMRDLLECGVHFGHQTRRWNPKMKKFIFGERKGIYIIDLQKTIRYFRYTYNIVRDAAAEGKTILFVGTKKQAGAAIKEFAEKCEMPYVNHRWLGGMLTNFDTIKQSIRKLEVIEQMETDGSMDLLTKKEAGMLKSKKAKLELYLGGIRNMKNLPDMVFVIDCVKEKIAVKEANRLGMPVIAPLDTNCDPDVVDFPIPGNDDAIRSIQLFCQEMSEAINEGKALRDQDSEEEIQNKEQDEVSQEEKDDILDEAMNEEDFEIPEDKE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: GATA_BRUSI
Sequence: MSELTALTIAEARDKLKAKAITATELTDAYLSAIDAANDAINAYVAVTHDQARSMAKASDERIAKGEAGALEGIPLGVKDLFATKGVHTQACSHILDGFKPEYESTVTANLWADGAVMLGKLNMDEFAMGSSNETSYYGPVKNPWRAKGSNADLVPGGSSGGSAAAVAAHLCAGATATDTGGSIRQPAAFTGTVGIKPTYGRVSRWGTVAFASSLDQAGPIARDVRDAAILMKSTASLDLKDTTSVDLPVPDYEAALGRSVKGMKIGIPREYRVDGMPGEIEELWQKGIQYLKDAGAEIVDISLPHTKYALPAYYIVAPAEASSNLARYDGVRYGLRVPGKDIADMYEQTRAAGFGKEVKRRIMIGTYVLSAGYYDAYYLRAQKVRTLIKKDFEDVFAKGVDAILTPATPSAAFGLADEVLANDPVKMYLNDIFTVTVNMAGLPGIAVPAGLNGQGLPLGLQLIGRPFEEETLFQAAHVIEQAAGRFTPAKWW
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: SYM_SHEB9
Sequence: MATSQRKILVTSALPYANGPIHLGHMLEYIQTDIWSRYQKLRGHECHYICADDAHGTPIMLKAQQLGIAPEDMIAQVNKEHQQDFADFNVAFDNYHSTHSEENRLMASDIYLKLRDNGYIKSKSISQLFDPEKSMFLPDRFVKGTCPKCKSPDQYGDNCDSCGATYSPTELINPKSAVSGATPVMKDTEHFFFDLPAFEGMLKEWTRSGALQVEMANKLDEWFEQGLQQWDITRDAPYFGFEIPDAPGKYFYVWLDAPIGYMGSFKNLCAKRPELSFDEFWGKDSTAEVYHFIGKDIVYFHSLFWPAMLHGSGYRQPNSVYAHGYVTVNGAKMSKSKGTFIKARTYLDHLDPEYLRYYYAAKLSSRIDDLDLNLEDFAQRVNSDLVGKLVNLASRTAGFITKRFDGKLAKINDTTLTEAFLAKQDVIADFYESREYGKAMREIMALADIANGFVADAAPWQMVKHDDQQEAAHQVCSNALNLFRILVTYLKPVLPRLAQDVEAFFQLPLTWDALSQDLAGHEIAPFKAMMQRVELDKVNAMVADSKDNLQVTADAPKTAAPEKIAKASSVSSEPLVSDPISETINFDDFAKIDLRIARIVKAEHVADADKLLKLQLDIGGETRQVFAGIKSAYSPEDLEGKLTVMVANLAPRKMRFGMSEGMVLAAGPGGSDLWILEPHEGAQPGMRVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.