PharMolix/UniProtQA huggingface dataset:
Protein: YIDD_IDILO
Sequence: MAKISKALRTIPIAFIKVYQWFISPLLGPRCRFYPSCSHYACEAIQKHGTIRGIGLAAVRISKCHPAHEGGYDPVPLAKQDAKPENNSESESLLNQPTETKSL
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RGI1_YEAS8
Sequence: MTKKDKKEVKVQTVTTEDGETVKVFEDLQGFETFIANETEDDDFDHLHCKLNYYPPFVLHESHEDPEKISDAANSHSKKFVRHLHQHIEKHLLKDIKQAVRKPELKFHEKSKEETFDKITWHYGEETEYHGRPFKIDVQVVCTHEDAMVFVDYKTHPVGAN
What is the function of this protein?
Involved in the control of energetic metabolism and significantly contribute to cell fitness, especially under respiratory growth conditions.
What are the official names of this protein?
Respiratory growth induced protein 1.
What is the protein family that this protein belongs to?
Belongs to the RGI1 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: LUXS_BACAC
Sequence: MPSVESFELDHTIVKAPYVRHCGVHNVGSDGIVNKFDIRFCQPNKQAMKPDVIHTLEHLLAFNLRKYIDRYPHFDIIDISPMGCQTGYYLVVSGTPTVREIIDLLELTLKDAVQITEIPAANETQCGQAKLHDLEGAKRLMNFWLSQDKDELEKVFG
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: KDUI_CALBD
Sequence: MEVRFAMHPSQFKALTTEQIRKEFLIENLFEYGKINMVYTHVDRVIVGSAVPTVEALVLEDGSQIGAQYFLERREIGIINIGSRGYVIADGQKFELDKKDGLYVGMSTKKLEFGSDDPSNPAKFYFVSTPAHKQYPTEKIDIKQTEATHLGSLSESNERTIYKYIHPDGVKSCQLVMGMTILEPNNVWNTMPCHLHDRRMEVYFYFDMPEDAFVLHLMGEPNETRHIIVRNEQAVISPSWSIHSGVGTKNYTFIWAMAGENQSYSDISPVPMKELK
What is the function of this protein?
Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.
What are the official names of this protein?
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase, 5-keto-4-deoxyuronate isomerase, DKI isomerase.
What is the protein family that this protein belongs to?
Belongs to the KduI family.
Protein: YIP5_YEAST
Sequence: MPSNNSSFLDIDDDLEGVDDFGNEPNPFDDATVPDSPNMNNSTAGKGSEFYNTTGSKAESAPLQGQMDPPAYDQVIGQNDNDGLGRNGLRPGLINYYSKYFQIDLTQFKKRLSAVLTFRNDHNSESNEDNTDLYGAVWITATVVMINFTMSRGLNFIISDVIEGVKTGEDIDRASQFKKLLHSIWLFYGYTFGVPFITMQVLNRDEHSERNRSFKSVPELISVYGYANLIWIPVCVILNILDMSKRLRTVQAIQWAIVALGWAQSSYFLNSQISSNNNTETQSNGKFSLSIIVVVALHTLFCLLFRFIIF
What is the function of this protein?
Possible role in vesicle-mediated transport.  May be involved in proper membrane localization of Rab GTPases.
What are the official names of this protein?
Protein YIP5, YPT-interacting protein 5.
What is the protein family that this protein belongs to?
Belongs to the YIP1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TRMB_LISIN
Sequence: MRVKHKPWAKDRLEEFPAIYIKNPEDFKGRWQEVFGNNNPIHIEIGSGKGQFISGMAKANPEINYIGIEMIESVLVSALDKAIEAEVPNLRLVARDAKLLEESFEKGEIAQIYLNFSDPWPKKRHTKRRLTNPTFLTIYERLLPKAGEIHFKTDNRSLFEYSLVAFSEYNMLLTFVSLDLHNSDYEGNIKTEYEEKFSAKGFPIYRLEAKFDRD
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: H2BE1_PSAMI
Sequence: MAPTGQVAKKGSKKAVKPPRASGGKKRHRKRKESYGIYIYKVLKQVHPDTGVSSRAMTIMNSFVNDIFERIAGEASRLTQYNKKSTISSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTTAK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.1, embryonic.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: KGX45_CENEX
Sequence: DRDSCVDKSQCAKYGYYYQCDECCKKAGDRAGTCEYFKCKCNP
What is the function of this protein?
Reversibly blocks Kv11/ERG potassium channels.
What are the official names of this protein?
Potassium channel toxin gamma-KTx 4.5, CexErgTx4, CexErg4, ErgTx4, Ergtoxin-like protein.
What is the protein family that this protein belongs to?
Belongs to the ergtoxin family. Gamma-KTx 4 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: UBIC_BORPE
Sequence: MTTPIPLARGWLPAAPSTLDPLRKYWLFRPGALTAGLRQLGHVRLRVLAEYPTGAPRDEADGMRIAAQSPVWVREVLMSIDGVDSVVARSLTPLRASHGVWQGMRRLLTRPLADMLYHDPGIHRSVFVCRRLAAGVPFHATAIARAPAGGPEPALWARRSAFWRAGQPLLVAECFLPAFWSLARAPVAPR
What is the function of this protein?
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
What are the official names of this protein?
Probable chorismate pyruvate-lyase, CL, CPL.
What is the protein family that this protein belongs to?
Belongs to the UbiC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAA_BARHE
Sequence: MTDVDSKVVGNASLEHPVISEEEGAAAFARVMAQLKAQVGIEAYTSWFGRLKLAEYSRNLVKLSVPTAFLRSWINNHYGSLLTNLWKQENSAILRVEVIVRGMKRVSKAVVCGKNAAPVVLEEKTASSFLENYTEHSVRGVEAGIFGSPLDSRYTFESFVEGSSNRVALAAARSIAEGHKSALRFNPLFIHASVGLGKTHLLQAIAAAALKRLKPARVIYLTAEYFMWRFATAIRDNDALSFKEQLRDIDLLIIDDMQFLQGKSIQNEFCHLLNMLLDSAKQVVVAADRPPSELESLDLRVRSRLQGGVALEIEAPDYEMRLEMLRQRLKVAQQDDNMIVISDEVLQYIAKTILGSGRDIEGAFNQLLFRQSFESDLSLERIDEFLGHLTRSGESKRIRIEEIQRAVARHYNVSKQDLLSNRRTRTVVKPRQVAMYLAKMLTPRSLPEIGRRFGGRDHTTVLHAVRKIEDLVCDDQTLAKELELLKRLIGEQAA
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMC_ECODH
Sequence: MKHYSIQPANLEFNAEGTPVSRDFDDVYFSNDNGLEETRYVFLGGNQLEVRFPEHPHPLFVVAESGFGTGLNFLTLWQAFDQFREAHPQAQLQRLHFISFEKFPLTRADLALAHQHWPELAPWAEQLQAQWPMPLPGCHRLLLDEGRVTLDLWFGDINELTSQLDDSLNQKVDAWFLDGFAPAKNPDMWTQNLFNAMARLARPGGTLATFTSAGFVRRGLQDAGFTMQKRKGFGRKREMLCGVMEQTLPLPCSAPWFNRTGSSKREAAIIGGGIASALLSLALLRRGWQVTLYCADEAPALGASGNRQGALYPLLSKHDEALNRFFSNAFTFARRFYDQLPVKFDHDWCGVTQLGWDEKSQHKIAQMLSMDLPAELAVAVEANAVEQITGVATNCSGITYPQGGWLCPAELTRNVLELAQQQGLQIYYQYQLQNLSRKDDCWLLNFAGDQQATHSVVVLANGHQISRFSQTSTLPVYSVAGQVSHIPTTPELAELKQVLCYDGYLTPQNPANQHHCIGASYHRGSEDTAYSEDDQQQNRQRLIDCFPQAQWAKEVDVSDKEARCGVRCATRDHLPMVGNVPDYEATLVEYASLAEQKDEAVSAPVFDDLFMFAALGSRGLCSAPLCAEILAAQMSDEPIPMDASTLAALNPNRLWVRKLLKGKAVKAG
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CECA_CULPP
Sequence: MNFNKLFVIVLLAALAFFGQAEAGGLKKFGKKLEGVGKRVFKASEKALPVVTGFKALGK
What is the function of this protein?
Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria.
What are the official names of this protein?
Cecropin-A.
What is the protein family that this protein belongs to?
Belongs to the cecropin family.
What are the subcellular locations of this protein?
Secreted.
Protein: FGD_MYCA1
Sequence: MAELKLGYKASAEQFAPRELVELAVAAEAHGMDSATVSDHFQPWRHEGGHAPFSLAWMTAVGERTTRITLGTSVLTPTFRYNPAVVAQAFATMACLYPGRIFLGVGTGEALNEIATGYQGEWPEFKERFARLRESVRLMRELWRGDRVDFDGEYYRLKGASIYDVPDGGVPIYIAAGGPAVAKYAGRAGDGFICTSGKGEELYKDKLIPAVKEGAAINDRNVDDIDKMIEIKISYDPDPELALENTRFWAPLSLTAEQKHSIDDPIEMEKAADALPIEQVAKRWIVASDPDEAVAKVKDYVDWGLNHLVFHAPGHDQRRFLELFEKDLAPRLRRLG
What is the function of this protein?
Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone.  Appears to have a role in resistance to oxidative stress, via its consumption of G6P that serves as a source of reducing power to combat oxidative stress in mycobacteria.
What are the official names of this protein?
F420-dependent glucose-6-phosphate dehydrogenase, FGD, G6PD.
What is the protein family that this protein belongs to?
Belongs to the F420-dependent glucose-6-phosphate dehydrogenase family.
Protein: PURL_LACLC
Sequence: MTLEMSPEQIQESKIYREWGLTDEEYLKIKDEILGGRLPNFTETGMYAVMWSEHCCYKNSKPVLKKFPTTGPQVLMGPGEGAGVVDIGDDLAVVFKAESHNHPSYVEPYEGAATGSGGIIRDIFSMGARPIAILDSLRFGPIDNGKTRHIVDQVTAGIAGYGNCIGIPTVGGEVAFDESYAGNPLVNVMCVGLIEHKHIQKGQAKGVGNSIFYVGAKTGRDGIHGASFASKEFGSGSETQRSAVQVGDPFMEKLLLEACIEVIQNHGDILVGIQDMGAAGLVSSTSEMASKAGSGLRLNLDNVPQRETEMIPYEMMLSESQERMVLCVKKGHEQEIIDLFKKYDLDAVNIGEVTDDGFYTLYHKGQMVAHVPVDSLAEDAPTYYREAKVPERIQKFTDSEKYLPEITDSAVSEIFKKLLAQPTIASKKSIYETYDSRVMTNTVVAPGSDAAVLRVRGTNKALAMTTDCNARYLYLDPEKGGAIAVAEAARNIVASGGKPLAITDCLNFGNPEKPEQFWELTTAADGISRSCLALDTPVISGNVSLYNETNGSAILPTPMIGMVGLIEDVKNITTQEFKKAGDLIVLVGQIFDDFSGSELQKMLTGEISGKIDFDLETEKVNQDFVLKAITDGLINSAHDLSEGGLAIALAESAFANGLGIDVEVDLSNAQLFSETQGRFVLSISPENQAAFEKLLTESSASSEVIGKVTDNGILKINELSISTDEAVSIYEGALPCLMK
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_RHOPT
Sequence: MNSIAHSTLAAASPTIRHDWTREEAAAIYHAPFADLMFRAQTIHRQTFDPNQVQCNQLLNVKTGGCAEDCGYCSQSAHHDTALPASKLMEPAKVIEAAKAARDAGATRYCMGAAWRSPKERDMAPVIEMVKGVKALGMEACMTLGMLTDDQAKQLADAGLDYYNHNIDTSEEFYASVVKSRSFGDRLDTLEKVQDAGIKVCCGGILGLGEKPTDRVEMLRTLANLPQHPESVPINMLIPIEGTPIAKTATPVDPFEFVRTIALARIMMPKSDVRLAAGRTAMSDEMQALCFLAGANSIFIGDTLLTTPNPGDSKDRALFNRLGITPRDDLGVHAHS
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: TRPA_STRCO
Sequence: MSGNVQLLNDTLAAAKSEGRAALIAYLPAGFPTVTGGIEAVKAALDGGADVVEVGLPHSDPVLDGPVIQTADDIALRGGVRIADVMRTVREAHEATGKPILVMTYWNPIDRYGVERFTAELAEAGGAGCILPDLPVQESALWREHADKHGLATVFVVAPSSRDARLAEITAVGSGFVYAASLMGVTGTRASVGAQAEDLVRRTRATTDTPVCVGLGVSNAAQAAEVAGFADGVIVGSAFVKRMLDAPDDAAGLEGVRALAADLAKGVRGQA
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: COP3_COPC7
Sequence: MSTPSSSLTTDESPASFILPDLVSHCPFPLRYHPKGDEVAKQTVHWLDSNCPDLTAKERKAMYGLQAGELTGYCYPYTTPERLRVVADFLNYLFHLDNISDGMMTRETAVLADVVMNALWFPEDYRPTKGQAAEELNPGKLARDFWSRCIPDCGPGTQARFKETFGSFFEAVNIQARARDEGVIPDLESYIDVRRDTSGCKPCWVLIEYALGIDLPDFVVEHPVIAALNQGTNDLVTWSNDIFSYNVEQSKGDTHNMIIILMEHHGHTLQSAVDYVGSLCQQTINTFCENKQQLPSWGPEIDDMVAKYVQGLEDWIVGSLHWSFQTRRYFGDEGQEIKQHRLVKLLTVAPPPPPPPPTPPPQSSDADTKKQKVKAQDGKGPVSDEEVWALVRAEQSKGSILESLFGFLTTSLSRIFFGYFFAYSH
What is the function of this protein?
Sesquiterpene synthase that catalyzes the formation of alpha-muurolene, and at lower level (+)-(R)-germacrene A and gamma-muurolene.
What are the official names of this protein?
Alpha-muurolene synthase, Gamma-muurolene synthase, Germacrene-A synthase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: CRIP2_PONAB
Sequence: MASKCPKCDKTVCFAEKVSSLGKDWHKFCLKCERCSKTLTPGGHAEHDGKPFCHKPCYATLFGPKGVNIGGAGSYIYEKPLAEGPQVTGPIEVPAARAEERKASGPPKGPSRASSVTTFTGEPNTCPRCSKKVYFAEKVTSLGKDWHRPCLHCERCGKTLTPGGHAEHDGQPYCHKPCYGILFGPKGVNTGAVGSYIYDRDPEGKVQP
What are the official names of this protein?
Cysteine-rich protein 2, CRP-2.
Protein: Y607_TREPA
Sequence: MTVCEGTRFSVLSRISPARVRVVKERRMRASALSVEEWYGSGDYQKSA
What are the official names of this protein?
Uncharacterized protein TP_0607.
Protein: RS19_RHIE6
Sequence: MARSVWKGPFVDGYLLKKAEKVREGGRAEVIKIWSRRSTILPQFVGLTFGVYNGSKHIPVSVNEDMVGHKFGEFSPTRTYYGHGADKKAKRK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: KDSB_SALDC
Sequence: MSFVVIIPARFSSTRLPGKPLVDINGKPMIVHVLERVRESGAERIIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLAEVVEKCGFSDDTVIVNVQGDEPMIPAVIIRQVAENLAQRQVGMATLAVPIHSAEEAFNPNAVKVVLDAEGYALYFSRATIPWDRDRFAKSLETVGDTCLRHLGIYGYRAGFIRRYVSWQPSPLEHIEMLEQLRVLWYGEKIHVAIAKAVPGTGVDTADDLERVRAEMR
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_STRA1
Sequence: MAQIKITLTKSPIGRKPEQRKTVVALGLGKLNSSVVKEDNAAIRGMVNAISHLVTVEEA
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: KARG_SCHAM
Sequence: MVDAAVLEKLEAGFKKLEASDSKSLLKKYLTREVFDKLKTKKTPSFGSTLLDCIQSGLENHDSGVGIYAPDAEAYTVFADLFDPIIEDYHGGFKKTDKHPPKNFGDVDTLANLDPNGEYVISTRVRCGRSMQGYPFNPCLTEAQYKEMEQKVSTTLSSLEGELKGQFYPLTGMSKEVQQKLIDDHFLFKEGDRFLQAANACRFWPSGRGIYHNDNKTFLVWCNEEDHLRIISMQPGGDLGQVYRRLVHAVNEIEKRIPFSHDDRLGFLTFCPTNLGTTLRASVHIKLPKLAADRTKLEEVAGKFNLQVRGSTGEHTEAEGGVYDISNKRRMGLTEYDAVKEMNDGILELIKIEGSL
What are the official names of this protein?
Arginine kinase, AK.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.
Protein: RR12_POPAL
Sequence: MPTIKQLIRNTRQPIRNVTKSPALGGCPQRRGTCTRVYTITPKKPNSALRKVARVRLTSGFEITAYIPGIGHNSQEHSVVLVRGGRVKDLPGVRYHIVRGTLDAVGVKDRQQGRSKYGVKKPK
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits (By similarity).
What are the official names of this protein?
30S ribosomal protein S12, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MTX2_HUMAN
Sequence: MSLVAEAFVSQIAAAEPWPENATLYQQLKGEQILLSDNAASLAVQAFLQMCNLPIKVVCRANAEYMSPSGKVPFIHVGNQVVSELGPIVQFVKAKGHSLSDGLEEVQKAEMKAYMELVNNMLLTAELYLQWCDEATVGEITHARYGSPYPWPLNHILAYQKQWEVKRKMKAIGWGKKTLDQVLEDVDQCCQALSQRLGTQPYFFNKQPTELDALVFGHLYTILTTQLTNDELSEKVKNYSNLLAFCRRIEQHYFEDRGKGRLS
What is the function of this protein?
Involved in transport of proteins into the mitochondrion.
What are the official names of this protein?
Metaxin-2, Mitochondrial outer membrane import complex protein 2.
What is the protein family that this protein belongs to?
Belongs to the metaxin family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane. Mitochondrion.
Protein: IHFB_PARXL
Sequence: MTKSELVAQLATRFPQLVLKDADFAVKTMLDAMSEALANGHRIEIRGFGSFGLNRRPSRVGRNPKSGEKVLVPEKYVPHFKPGKELRERVDRRAGEPLKAEDPDDDL
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: Y515_ACIBY
Sequence: MPSFDIVSELELFEVNHAVQNTQKEIATRFDFRGHDVSIELNEKNKEIKISTESDFQCEQVYNMLENHFYKRKIDVQALDPQKATASGKNFVQVIKLKDGLDSDTAKKINKAIKESGIKVQSSIQGDKIRVTDKKRDTLQQVMAFLREQQFGLPLQFNNFKD
What are the official names of this protein?
UPF0234 protein ABAYE0515.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: RSP7_CAEEL
Sequence: MSGEEKEKVKILHVANISTSATRDHIYNMFNYLGKIQDLKVYPSEGNITANTLLKTAFIKFDDERCVEVAQHLTNTVVIDCAIVCLPYPNPVIPDEESFFNSGGSTTAGQRQLPPHVTNKIQESDDGSALLITVDPTLEQLGLPAYPPLPADTDSAKVEEIRRTVYVGNLPKGVDGNEVLELFNMYFGEVMYARMASGPDALPCAYAYVEFSQQASVCNALQNDGFEFKERPLKIQHSRVAIIKPQAKTDEQALGEIEEAIRMGRNGDDRDRRRSRSPRRRRSPSPRRRRDSRDRDRDRDRDRRRSRDRRSRSRDRDRDRDRKRSRSRDRKRRSRSRDNKDRDRKRSRSRDRRRRSKSRDRKRERSRSRSKDRKRDKKRSRSRSPEKRRDKEDRKTEKKENENESSLREKLLEKKAARKDSSDDEWEEKPTPTNGEVKNEEIGNGDVVMASE
What are the official names of this protein?
Probable splicing factor, arginine/serine-rich 7, p54.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CPN2_HUMAN
Sequence: MLPGAWLLWTSLLLLARPAQPCPMGCDCFVQEVFCSDEELATVPLDIPPYTKNIIFVETSFTTLETRAFGSNPNLTKVVFLNTQLCQFRPDAFGGLPRLEDLEVTGSSFLNLSTNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAALESLHLQGNQLQALPRRLFQPLTHLKTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFCLERLWLQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQLETVAEGTFAHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPALFQNLSKLELLSLSKNQLTTLPEGIFDTNYNLFNLALHGNPWQCDCHLAYLFNWLQQYTDRLLNIQTYCAGPAYLKGQVVPALNEKQLVCPVTRDHLGFQVTWPDESKAGGSWDLAVQERAARSQCTYSNPEGTVVLACDQAQCRWLNVQLSPQQGSLGLQYNASQEWDLRSSCGSLRLTVSIEARAAGP
What is the function of this protein?
The 83 kDa subunit binds and stabilizes the catalytic subunit at 37 degrees Celsius and keeps it in circulation.  Under some circumstances it may be an allosteric modifier of the catalytic subunit.
What are the official names of this protein?
Carboxypeptidase N subunit 2, Carboxypeptidase N 83 kDa chain, Carboxypeptidase N large subunit, Carboxypeptidase N polypeptide 2, Carboxypeptidase N regulatory subunit.
Protein: TRUA_SHEB9
Sequence: MRIALGIEYDGNGYFGWQRQAEVDSVQAQLERALSIVANEPIGVFCAGRTDAGVHATGQVVHFETNAIRNEGAWTLGVNANLPDNIAVRWVKEVDDSFHARFSATARRYRYVIYNHSFRPGILRHGVSHYHGDIDADRMHQAAQALLGEQDFTSFRAVQCQSKTPFRNVHCVNVTRQGMYVIVDIAANAFLHHMVRNIVGSLLEIGLGNQPLTWMGDLLALKDRNQAAATAKPHGLYLVDVTYPEQYQLPKLALGPLFMLD
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: TDL1_ARATH
Sequence: MRMEHIYKFQHWLFFIGLGVLLSLSLSVKANDFEGSNDRRSIALKARSFVSINENRTALSRKLLLSPDIGDGTNRIGQDCSKDDIVLFQGSTNPLPSGVPSYTVEIFNSCVSDCNIAEIHVSCGWFSSVRLVNPRVFRRLDYDDCLVNDGQPLGPGQSLSFQYANSFSYPLSVASVSCF
What are the official names of this protein?
TPD1 protein homolog 1, TPD1-like protein 1, AtTDL1.
Protein: SSRP_TRIEI
Sequence: MAKKSGEGQKIISDNRQARFNYHIIETYEAGVALQGTEVKSIREGKVNLRDGYALIRNNEAWLLNVHISPYQKAGDFFNHEPRRSRRLLLHKQEIRKLIGKVEQQGLTLVPLRMYFKRGWVKVDIALAQGKKLYDKRETIKRRDDKRAMQRAIKQY
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: IMDH_SCHPO
Sequence: MSAFKPYTEALEVLKKYEKKDGLSIDDLIRHNFQGGLTFNDFLILPGYIDFVPNNVSLETRISRNIVLKTPFMSSPMDTVTEDQMAIYMALLGGIGVIHHNCTPEEQAAMVRKVKKYENGFILDPVVFSPQHTVGDVLKIKETKGFSGIPITENGKLRGKLVGIVTSRDVQFHKDTNTPVTEVMTPREELITTAEGISLERANEMLRKSKKGKLPVVDKDDNLVALLSLTDLMKNLHFPLASKTSDTKQLMVAAAIGTRDDDRTRLALLAEAGLDAVVIDSSQGNSCFQIEMIKWIKKTYPKIDVIAGNVVTREQTASLIAAGADGLRVGMGSGSACITQEVMACGRPQATAIAQVAEFASQFGIGVIADGGIQNVGHMVKSLSLGATAVMMGGLLAGTTESPGEYYVREGQRYKSYRGMGSIAAMEGTGVNKNASTGRYFSENDAVRVAQGVSGLVVDKGSLLRFLPYLYTGLQHALQDIGTKSLDELHEAVDKHEVRFELRSSAAIREGDIQGFATYEKRLY
What is the function of this protein?
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
What are the official names of this protein?
Inosine-5'-monophosphate dehydrogenase, IMP dehydrogenase, IMPD, IMPDH.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family.
What are the subcellular locations of this protein?
Cytoplasm.