PharMolix/UniProtQA huggingface dataset:
Protein: ERA_TROWT
Sequence: MVVSRSPGGYRSGIITLVGRPNVGKSTLINSLVGEHLSITSDKPQTTRRIIRGVISRMNAQIAITDTPGIHKPKTPFGKGLNEMTTCALSASDSIGICLPVNQKIGSGDRFILDKVEAIGPYKKIAIVTKIDRVEKRDLLLKLSEISDLGCNFAAVVPVSAKRAVQIDLLKDVFFENCLNFSEKLFFDHEKPSVSDQISELIREKALCLLEQEIPHSLLVEVEEILTDSNRVFIHANLYVERNSQKMIVLGKGGRTIKNISITSRLAIESFLGKKVYLRLIVKVVKNWQKSESFLGKIYLS
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: QUEA_MARN8
Sequence: MNVSDFHFDLPDELIARYPLKERSASRLLSLDGLSGQTTHLKFTDLPDLLQPGDLLVFNNTRVIPARLFGQKETGGKVEILVERLLGEKELLAHTRSSKSPKEGQRLLLEDGAALRMLARKDALFHFVYEGDEAFLDVLERIGHMPLPPYMEREDEQSDRERYQTVYAKEAGAVAAPTAGLHFDDVVLSALKAKGIEFAYVTLHVGAGTFQPVRVDKIEDHVMHSEIAHVPEETVKAVNEARARGGRVVAVGTTSVRSLESASRAGRLQEFRGDTDIFIYPGYRFQTVDAMITNFHLPESTLIMLVSAFAGYNNIMSAYREAVEQKYRFFSYGDAMFLTAQEPSRGMMLGTDSAEPHQTESRGESQ
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR3_CUSOB
Sequence: MGQKINPLGLRLGTNQDHYSIWFSQPKAYSKSLQEDQKIRSFIRKYIQNMKISPSGVEGLARISIYKRIDLIELRIFLGFPKLLLENRPQGLEKLQITLQKELNCGNRRLNIVITKVEKPYSNPNILAEFIAGQLKNRVSVRQAMKKAIELAEEADTKGIQVQVAGRLNGQDIARVQWIREGRVPRQTIRATFDYCSYPVRTIYGILGIKIWIFVGEAK
What are the official names of this protein?
Plastid 30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Plastid.
Protein: DNAK_ELUMP
Sequence: MARIIGIDLGTSNTAAAAMEGGRATIIPSAEGSSIGGKAFPSYVAFTKDGQRLVGEPARRQAIANPEGTVTAFKRRMGEDYKFTLRGQEFTPQQLSAFVLQKVKKDAEAFLGEPVEKAVITVPAYFNDNQRQATKDAGRIAGLEVVRLVNEPTAAALAYGIDKAGKEQKIMVFDLGGGTLDVTIMEMGKEGTFDVLSTSGDTKLGGTDMDNAIIEWMVSEFKKSTGIDLSADKQAAQRLKDAAEKAKIELSTTMETDINLPFISAGADGPKHLELKLSRAKLESLVDSIVKRCGASIDQALNDSSLKSTEIDKIILVGGPTRMPIVQKYVEDHAGKKIERGIDPMECVATGAAVQAGILTGDVKDVLLLDVTPLSLGLETLGGVTTRLIERNTTIPVRKTQVFSTASDNQPAVTINVLQGERPMAKDNVPLGKFDLDGIPPAPRGVPQIEVTFDIDANGILNVSAKDLGTNKQQHITITSKTKLSDDEVQKFVKEAEKFADEDKKTKERVDAKNEADSVLFQTEKALKEHGDKVPQEDRLNIDRALGDLKEALKGDDVERIKKAKDDALAASQKLGEIIYKESQAKAQGAAGPQPGAQAQGQPNDGGKEDVVEAEVVDK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: LSM6_BOTFB
Sequence: MENGALQQGEGKDPSSFLSEIIGSKVIVKLNNSLVFKGELQSVDGYMNIALEKCEEWVHGKKKTVHGDAFVRGNNVMYISADESA
What is the function of this protein?
Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates.  Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway.  Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs.  LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 di-snRNP, spliceosomal U4/U6. U5 tri-snRNP, and free U6 snRNP).  It binds directly to the 3'-terminal U-tract of U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes.  LSM2-LSM8 probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping, and in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA (By similarity).
What are the official names of this protein?
U6 snRNA-associated Sm-like protein LSm6.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: LAC2_MOUSE
Sequence: QPKSTPTLTVFPPSSEELKENKATLVCLISNFSPSGVTVAWKANGTPITQGVDTSNPTKEGNKFMASSFLHLTSDQWRSHNSFTCQVTHEGDTVEKSLSPAECL
What are the official names of this protein?
Ig lambda-2 chain C region.
Protein: RS20_GLUOX
Sequence: MANTASARKRIRQNERRRERNVARMSRMRTFIKKVELAIQAGDKSAAAEAFKVAQPEMQRAAGKGVIAKNTISRKLSRLSARVKALATA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: DSRE_ALLVD
Sequence: MKFALQINEGPYQHQASDSAYQFAKAALEKGHEIFRVFFYHDGVNNSTRLTTPPQDDRHIVNRWAELAEQYELDMVVCVAAAQRRGIVDEGEASRNGKDATNIHPKFRISGLGQLVEAAIQADRLVVFGD
What is the function of this protein?
Not known.  Could be involved in the oxidation of intracellular sulfur.
What are the official names of this protein?
Putative sulfurtransferase DsrE, Intracellular sulfur oxidation protein DsrE.
What is the protein family that this protein belongs to?
Belongs to the DsrE/TusD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR9_SHEWM
Sequence: MNNARPIRRALLSVSDKTGILEFAKSLHAQGVELLSTGGTARLLADNGVPVIEVSDHTGHPEIMDGRVKTLHPKVHGGILARRGIDELVMEQNNIKPIDLVAVNLYPFAETVAKEGCTLADAVENIDIGGPTMVRSTAKNHKDTTIIVNAHDYDRVIAEMEANQGSTTLETRFDLAIAAFEHTAAYDGMIANYFGTKVPAHSQDECHERSLCAEDSKFPRTYNTQLVKKQDLRYGENSHQTAAFYVDTNIDEASVATAVQLQGKALSYNNIADTDSALECVKEFSEPACVIVKHANPCGVAIGENLLEAYNRAFQTDPTSAFGGIIAFNAELDAETAAAIVERQFVEVIIAPKVCQAARDVVAAKANVRLLECGEWANKTTSLDYKRVNGGLLLQDRDQGMVGLDEVKVVSKRQPTEAEMKDLMFCWKVAKFVKSNAIVYAKNSMTIGVGAGQMSRVYSAKVAGIKAADEGLEVQDSVMASDAFFPFRDGIDAAAAAGISCIIQPGGSIRDEEIIAAADEHGMAMVFTGMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: PANB_SHELP
Sequence: MSKITSSTLLKFKQEGKKFTALTAYDASFAGAFDSEGIDVLLVGDSLGMVLQGHDDTLPVTVEDIVYHTRCVRRGIKRSLLIADMPFMSYATPEQAMTNATALMQAGANMVKLEGGHWLLETVTKLTERGIPVCAHLGLTPQSVHVFGGFKVQGRDADNAQRIIDEAKAIEAAGAQLLVLECIPAALAKSITEALTIPVIGIGAGADTDGQILVMHDVLGISSGYIPRFSKNYLAQTGEIRSAIRAYIEEVDTGVFPAAEHTFS
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINE_RHOCS
Sequence: MNLMDFFRRNKEPTATTAKDRLQIVLAHERADRNAPDFLPALQKELLAVIKKYVPIDDDKVAVKLERESGCSMLEVNVELPAPTKGAPRQPAATAAG
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: SMG_BORA1
Sequence: MFDILVYLFENYYTPQACPAADVLAKRLAAAGFEHEDIDDALGWLYGLAETTERCVELAQAPASGFRVYTDAEYQQLGSASIGFITFLESAGVLPAPLREIVIDRALASPEAPVSLSKIKIIALMVLWSQEAEIDNLVLEELLDDEEARRLH
What are the official names of this protein?
Protein Smg homolog.
What is the protein family that this protein belongs to?
Belongs to the Smg family.
Protein: RL211_ARATH
Sequence: MPAGHGVRARTRDLFARPFRKKGYIPLSTYLRTFKVGDYVDVKVNGAIHKGMPHKFYHGRTGRIWNVTKRAVGVEVNKQIGNRIIRKRIHVRVEHVQQSRCAEEFKLRKKKNDELKAAAKANGETISTKRQPKGPKPGFMVEGMTLETVTPIPYDVVNDLKGGY
What are the official names of this protein?
60S ribosomal protein L21-1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL21 family.
Protein: WTR25_ARATH
Sequence: MESTVEREAWKAHVAMIGVQLFNGGYHVITKVALNVGVNQLVFCVFRDLIALSILAPLAYIRDKRTRPPLNRQFLLAFFFLGLTGIFGNQLLFLIGLNYTNPTYAAAIQPSIPVFTFILALIMGTERLNLFKLEGQAKVGGTLICVAGAVLMVLFRGLALFGETEAESLGHGESRHTETSGHFMSGFFNGLGRWNLGVLCLIGNCTCMAAFLAIQAPVLKKYPANLSVTAYSYFFGTMFMVTSAFFMTNESTNWSLTRSEFFAVVYAGVIASALNYGLLTWSNKILGPSLVALYNPLQPAASAFLSRIFLGSPIYLGSILGGCAIIAGLYSVTWASYKEKKAAAAMAVIPITSKEAEPLIYKDHKNKPIGHLFTKSPISSPKSDD
What are the official names of this protein?
WAT1-related protein At3g45870.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Plant drug/metabolite exporter (P-DME) (TC 2.A.7.4) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SHG1_SCHPO
Sequence: MDRDVTLNVDELVSKFKKEGHFDRLRKQILETVNEKESGPLLDRLKKIIDEEMVKDRTLKSKDQFRAAPLIAGAVDRSSLYEDSMEHIRSNVLSDQDLREVIYNSLEQIGIEQIEHEDEEKLLNSKTMDGRK
What is the function of this protein?
The Set1 complex specifically methylates 'Lys-4' of histone H3.
What are the official names of this protein?
Set1 complex component shg1, Set1C component shg1, COMPASS component shg1, Complex proteins associated with set1 protein shg1.
What is the protein family that this protein belongs to?
Belongs to the SHG1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: CHED_CERS4
Sequence: MTRCDDSPSASQISITHVTQGSCVASSSPNEVYATILGSCICTCMCDPVAGVGGMNHFLLPSADVEDAQHLRYGSHAMELLINALLKLGAARQRIEAKIFGGAMMTPQLGAIGQANAAFARRYLKDEGIRCTAHSLGGNRARRIRFWPKTGRVQQMFLGSEDVVPNEQPQFRLQGGAGDVTFFDRHNNAEMPDPIKEPR
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: MUTL_VIBCH
Sequence: MTIRILPARLANQIAAGEVVERPASVVKELVENSLDAGATRIDIDLEKGGAKLIRIRDNGSGIDKDELGLALSRHATSKIHTLDDLEAIMSLGFRGEALASISSVSRLTLTSRTVAQEEAWSAYSEGRDMAVKLQPAAHPVGTTVEVLDLFFNTPARRKFLRTEKTEFTHIDELLKRIALSRFDVSFTLRHNGKIVRQYRAATTLPQQEKRLAAVCGNPFVQHMLRIELEHQGLKLHGWITTPEGARQQSDLQYCYVNGRMMRDKLINHAIRQSYETSLRVDQFATYVLFIELDPHQVDVNVHPAKHEVRFHQARLVHDFIYQALSSALVQGAQVMAPTINEGAFHLPHCAEEVNPPVVPMIDTTQQERVWQAVQNTPDYPRKAPRDNDRDESDNPQVRERAVSNPWVASPKTASTGKERYGSASVSKKEAAVYQTLMQTPDLSDEEPSTASTIVSSIEAVKANIAIEKLGKAIQVVAGQYLLMSSPQGCVLISLYQAQQLKLRGLLNAQHGALKAQPLLVPLALKLNESEWQVAQRHSSALLQLGIELKSRTNHSIMVMAVPQPLRQQNLQQLLPDLLSYAASCSESQALSHQALADWLTQRIVVEKRDYTLAEAIGLIAELEQLWQGNLPLQDPHFITLVDFSASITALHS
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity).
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: ILVC_STAAR
Sequence: MTTVYYDQDVKTDALQGKKIAVVGYGSQGHAHAQNLKDNGYDVVIGIRPGRSFDKAKEDGFDVFPVAEAVKQADVIMVLLPDEIQGDVYKNEIEPNLEKHNALAFAHGFNIHFGVIQPPADVDVFLVAPKGPGHLVRRTFVEGSAVPSLFGIQQDASGQARNIALSYAKGIGATRAGVIETTFKEETETDLFGEQAVLCGGVSKLIQSGFETLVEAGYQPELAYFEVLHEMKLIVDLMYEGGMENVRYSISNTAEFGDYVSGPRVITPDVKENMKAVLTDIQNGNFSNRFIEDNKNGFKEFYKLREEQHGHQIEKVGRELREMMPFIKSKSIEK
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: RL31_THEFY
Sequence: MKPGIHPDYHVTQVTCTCGNSFVTRSTAPNGVIRAEICSSCHPFYTGKQKILDTGGRVARFEKRFGKRK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: RL21_DESAP
Sequence: MYAIIETGGKQLCVREGDTVRVEKLAVEDGAEVVFDRVLLVSTEEGLKIGRPLVLGARVTGRVQKQGRARKIIVFKYKAKKNYRRKQGHRQPYTQVVIEKIEL
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: IP6K3_HUMAN
Sequence: MVVQNSADAGDMRAGVQLEPFLHQVGGHMSVMKYDEHTVCKPLVSREQRFYESLPLAMKRFTPQYKGTVTVHLWKDSTGHLSLVANPVKESQEPFKVSTESAAVAIWQTLQQTTGSNGSDCTLAQWPHAQLARSPKESPAKALLRSEPHLNTPAFSLVEDTNGNQVERKSFNPWGLQCHQAHLTRLCSEYPENKRHRFLLLENVVSQYTHPCVLDLKMGTRQHGDDASEEKKARHMRKCAQSTSACLGVRICGMQVYQTDKKYFLCKDKYYGRKLSVEGFRQALYQFLHNGSHLRRELLEPILHQLRALLSVIRSQSSYRFYSSSLLVIYDGQEPPERAPGSPHPHEAPQAAHGSSPGGLTKVDIRMIDFAHTTYKGYWNEHTTYDGPDPGYIFGLENLIRILQDIQEGE
What is the function of this protein?
Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5).  Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4.
What are the official names of this protein?
Inositol hexakisphosphate kinase 3, InsP6 kinase 3, Inositol hexaphosphate kinase 3.
What is the protein family that this protein belongs to?
Belongs to the inositol phosphokinase (IPK) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CC110_HUMAN
Sequence: MSPEKQHREEDEVDSVLLSASKILNSSEGVKESGCSDTEYGCIAESENQIQPQSALKVLQQQLESFQALRMQTLQNVSMVQSEISEILNKSIIEVENPQFSSEKNLVFGTRIEKDLPTENQEENLSMEKSHHFEDSKTLHSVEEKLSGDSVNSLPQSVNVPSQIHSEDTLTLRTSTDNLSSNIIIHPSENSDILKNYNNFYRFLPTAPPNVMSQADTVILDKSKITVPFLKHGFCENLDDICHSIKQMKEELQKSHDGEVALTNELQTLQTDPDVHRNGKYDMSPIHQDKMNFIKEENLDGNLNEDIKSKRISELEALVKKLLPFRETVSKFHVHFCRKCKKLSKSEMHRGKKNEKNNKEIPITGKNITDLKFHSRVPRYTLSFLDQTKHEMKDKERQPFLVKQGSIISENEKTSKVNSVTEQCVAKIQYLQNYLKESVQIQKKVMELESENLNLKSKMKPLIFTTQSLIQKVETYEKQLKNLVEEKSTIQSKLSKTEEYSKECLKEFKKIISKYNVLQGQNKTLEEKNIQLSLEKQQMMEALDQLKSKEHKTQSDMAIVNNENNRMSIEMEAMKTNILLIQDEKEMLEKKTHQLLKEKSSLGNELKESQLEIIQLKEKERLAKTEQETLLQIIETVKDEKLNLETTLQESTAARQIMEREIENIQTYQSTAEENFLQEIKNAKSEASIYKNSLSEIGKECEMLSKMVMETKTDNQILKEELKKHSQENIKFENSISRLTEDKILLENYVRSIENERDTLEFEMRHLQREYLSLSDKICNQHNDPSKTTYISRREKFHFDNYTHEDTSSPQSRPLASDLKGYFKVKDRTLKHH
What are the official names of this protein?
Coiled-coil domain-containing protein 110, Cancer/testis antigen 52, CT52, Cancer/testis antigen KM-HN-1.
What are the subcellular locations of this protein?
Nucleus.
Protein: AROB_STRSY
Sequence: MKLTVNLPNTPYDILIQRGSLAQTGAWVKELWKPQKIAIITDDHVGSLYRETVQSSLEQAGFETIVFEFPEGEASKNLDTVNQAYEFLVKNGMTRSDGIIALGGGVVGDLAGFVASTYMRGIHFLQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFCQPDGVLIDPDTLKTLGKRELIEGMGEVVKYGLIDDVELWETLDQLDGSVESILEHADYIIYHSCEVKRKVVVEDELDNGVRLYLNFGHTIGHAIEATAGYGQVMHGEAVAIGMVQISRAAEKKGLMPAGMTAKIIAMCEKFGLPTTHQPWNVDELYASLTHDKKTRGKTIKLVIVPQLGQAAIHQIPMEEMLEFLQV
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_SHEPC
Sequence: MSQLQVRHDWKREEIEALFALPMNDLLFKAHSIHREVYDPNEVQISRLLSIKTGACPEDCKYCPQSARYDTGLEKERLLAMETVLTEARSAKAAGASRFCMGAAWRNPKEKDMPYLKQMVQEVKALGMETCMTLGMLSAEQANELADAGLDYYNHNLDTSPEYYGDVITTRTYQNRLDTLTHVRASGMKVCSGGIVGMGEKATDRAGLLQQLANLPQHPDSVPINMLVKVAGTPFEKLDDLDPLEFVRTIAVARILMPLSRVRLSAGRENMSDELQAMCFFAGANSIFYGCKLLTTPNPEESDDMGLFRRLGLRPEQGAVATLDDEQAVLAKAAAHQDKSTAQFYDAAAL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: DUSB_PASMU
Sequence: MRIGSYQLKNRIFLAPMAGITDQPFRRICTHYGAGLTFSEMMSTNPQVWHTEKSKLRLAHHQEAGINAVQIAGCDPDEMAKAAQINVEYGAEIIDINMGCPAKKVNRKMAGSALLQYPDLVKQILNKVVKSVTVPVTLKIRTGWDKDNRNCLEIAKIAEQCGIQALTIHGRTRSCMFEGEAEYDNIKAVKEQLSIPIIANGDITSAEKAKYVLDYTNADAIMIGRGSLGNPWLFRVMESLIEKDSIVLEPSLNEKCNVILQHIQELHQFYGVEKGCRIARKHVAWYLQGIQPNPVFRQAFNAITDPKEQLIALEGFFNLILMDKEKNVRTTT
What is the function of this protein?
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.
What are the official names of this protein?
tRNA-dihydrouridine synthase B.
What is the protein family that this protein belongs to?
Belongs to the Dus family. DusB subfamily.
Protein: Y011_CLOPS
Sequence: MKNKILNTVLISILLLVVVFFVSTNFIINVQWFKEVGYLNVFFTKLIAICKLFVPIFILYFCVIAIYLFTLRKSIRSLVGDTKFKSVKKYFLLSNLVISILGAGATATTQWYKILQFTNAVPFGEVDPIFNKDISFYVFKLPLVQSLFSTAISLIIILVLITVIIYLALGFKDKIYQNKDNVININSKTYGIRKFAGKQLAVLASVLSLLIGCSYLLKSYNLVYSTRGVSYGAGYTDVKITMIFYKVIAIACVISSIVVFISILKLKFRPIIISIASIAVLIVLEPVVAIFTQQFVVKPNEMELEKPYISYSIDATKKAFNIDEIEVKEMEPNENITSEKLEDNKDIIENLKVNSTGPLLSFYQQVQLIKNYYEFNDADTDRYNINGKYTQVFVSPREINREAMTTWQNKHLRYTHGYGLAMSRVNSVTEFGQPDFVMKDIPTVNTTDINLENPRIYFGESDNDYVIVNTEGGEFDYPTGDTENTFNYNGTGGLKMTPFNRVLFSIYERNPKILMSSSITSESRIILNRNIVKRVQEIAPFLTYDSDPYIVVHDGRLVWMMNAYTSTDKYPFSEPHEGVNYIRNSVKVVVDAFNGNVDFYVTDENDPIINCYLKIYKGLFKPLSEMPEDLKEHFRYPQDLFELQSKVLTKYHVDDPIKLFTEEDLWDRSLDVVKHGGENLSQGDEGKEESILNKAKENKNNEAENEGLYLMTKLPDEENVEMMLLDYFNMRGKQSMVALLGARMDGDNYGELVMYKFPPQRTIYSPILFKNRIQQDPNISKEISLWAGKGSEVIYGDIIIVPIEDSLLYLNTIYLKANSENSMPEMKRVILSNGDKIVIEENIEKALLKLFNYNSFEENKNSNKDETSNTEITSDNSGVKEAADLFNKAIEAQKNGDWATYGEFINKLGDVLNKMSHD
What are the official names of this protein?
UPF0182 protein CPR_0011.
What is the protein family that this protein belongs to?
Belongs to the UPF0182 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y389_CLOPE
Sequence: MNDNKKLGVIALAGVVISAMLGGGVYNLPQNMAQSASAGAILISWIITGIGIWFIANTFRILAAARPDATTGIYTYGELGFGKFTGFLMAWGYWICNSFANVGYAVLLMDSLNYFFPPYFKGGNNWLSIACGSLVLWIIFFIVLAGVKQASALNVIGTIGKLLPLAIFLLVLLFSFRFSTFFTDFWGLKTVAKVHDTNLGGILPQVKSTMLVTLWVFTGIEGAVVVSGRAKSQKDVSKATFLGFITCLLIYTLLSLLPLGVYSQGEISKMAPPSTAAVLMDLIGNWGSVIMNLGVIIAILSSWLIWTVMLSELPFAAAQSGTFPKIFAKENKNESPSFSLLASTIIMQIILILVHFAGNAWNMMLSITSVMALPCYLVSTLYLFKITYKNENYPTDIFAKRKYAMITAILGSIYGVWLIYAAGINYMLIAIVIYALGIPVFIKARRETSPNEKEFTKVERYFAIVLIILALIGLVYLFKFM
What is the function of this protein?
Could be an amino acid transporter.
What are the official names of this protein?
Putative amino-acid transporter CPE0389.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: THIG_CROS8
Sequence: MLRIADKTFQSRLFTGTGKFASSSLMLEAIRESGSEMATLAMKRVDLLRRDDALLAPLQASGVALLPNTSGAKTAEEAVFAAQLAREALGTHWIKLEIHPDARWLLPDPIETLRAAEKLVAQGFVVLPYCGADPVLCKRLEEAGCAAVMPLGAPIGSNQGLQTRALLEIIIAQASVPVVVDAGIGAPSHAAEALEMGADAVLVNTAIAVARDPVAMARAFRQAVEAGRTGFEAGLGARVFQAQATSPLTGFLEAQA
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SHU7_ECOLX
Sequence: MKKYDRGWASLETGAALLIVMLLIAWGAGIWQDYIQTKGWQTEARLVSNWTSAARSYIGKNYTTLQGSSTTTTPAVITTTMLKNTGFLSSGFTETNSEGQRLQAYVVRNAQNPELLQAMVVSSGGTPYPVKALIQMAKDITTGLGGYIQDGKTATGALRSWSVALSNYGAKSGNGHIAVLLSTDELSGAAEDTDRLYRFQVNGRPDLNKMHTAIDMGSNNLNNVGAVNAQTGNFSGNVNGVNGTFSGQVKGNSGNFDVNVTAGGDIRSNNGWLITRNSKGWLNETHGGGFYMSDGSWVRSVNNKGIYTGGQVKGGTVRADGRLYTGEYLQLERTAVAGASCSPNGLVGRDNTGAILSCQSGTWRKSNSGSTVITGRIANGQQIPLPTGFSASQCSWSVSNAENPQGWKPNYFAGSVATYDANRIVKCGFYDEYNFHKGTFRADLTGKCSYVVACQN
What are the official names of this protein?
Shufflon protein D'.
Protein: ZNF34_BOVIN
Sequence: MAALDLCALPQAEVTFEDVAVFLSQEEWGLLGPAQKGLYREVMLETYRNLVSLGAGLAGPKPEVIAQLEQGDELWVLDMHGAEQPSVDGSAHGTRTENQEVTSGEMLFGRELDPLRGSVLRGPEPGEVHERVREPEGRLDRPGEQRGPRLVTLANEECGLESGGNLRSRSRPVPDQRPHKCDICEQSFEQRSYLNNHKRVHRCKKTNIVHDSGEIFAANLVKEDQKIPVGKRLYYCGCCGKAFRYSANLVKHQRLHSEEKPYKCEECGKAFHQSCELISHRRMHSGEIPYRCDECGKTFNQRPNLMKHQRIHTGEKPYKCSECGKHFSAYSSLIYHQRIHTGEKPYKCSDCGKAFSDGSILIRHRRTHTGEKPYECKECGKGFTQSSNLIQHQRIHTGEKPYKCNECEKAFIQKTKLVEHQRSHTGEKPYECNDCGKVFSQSTHLIQHQRIHTGEKPYKCSECGKAFHNSSRLIHHQRSHHGEKPYKCADCKKAFSQGTYLLQHRRIHTGEKPYTCGECGKAFRHSSNMSQHQRIHLREDFSL
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 34.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KRE28_ZYGRC
Sequence: MKSDLDGYEVRIKSLENQTAHYSEQALLEQEQRVLASLREITQNVIAMGQENSLVEIKGELESKEESELVIDPSGFQEKIDTFVELVELLKVTHLEQETLDNFLRYTISSSNLLQINSVQDAKYVELESQVKELEQGTLESHKREIEATKGQIKNLCQELSMAQDSINETFLDTSNALEECDALLNELTQLRMEKQTSEEADTIEDDPVSQTYEDWESLQKSKLELRLLEEETSRLQSRVESYEDYQKRSRQLSNNDPRMLQNHKALELLVELWMTKFLPQPGISHLELFPQSRKFQFDVEPTFTVVITLADQTTFQNVQVYRKDAKSLVMDHGLNDEIKNSYLGTNNIYNGLNDIIHTLQRRVQAKGSN
What is the function of this protein?
Required for kinetochore binding by a discrete subset of kMAPs and motors.  Involved in kinetochore-microtubule binding and the spindle assembly checkpoint (By similarity).
What are the official names of this protein?
Spindle pole body component KRE28.
What is the protein family that this protein belongs to?
Belongs to the KRE28 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Chromosome, centromere, kinetochore. Note=Localizes to the nuclear side of the spindle pole body.
Protein: DTNK_PECAS
Sequence: MPNVQQSAGQVLVVADDFTGANDAGVGLAQHGARVSVVFDVNTLHADLLGDAVVINTDSRAARDDVASQRTAAAVAAWQAVGGKGWIIKKIDSTLRGNLGAEVAAALSAADVPVALIAAASPTLGRVTRQGEVWVNGRRLTDTEFASDPKTPVTSASIAARLAEQTALPVAEIHLDEVRQANLAHRLQQLADEGTRLIILDTDVQDDLTHIVNAARALPFRPLLVGSAGLSDALATAQDFTRKTEKPLLAVVGSMSDIAQKQIAAARLRSDVTLVEIDINALFSPDSSTVMASQCEDALKALTNGHHCIIRTCHNENQRFEIDARCRELGLSRQQLGETISHYLGELTRSIVQALDSLAADGTRRRLPGGLYLSGGDIAIAVATALGATGFQIKGQIASCVPWGYLLNSIVGMTPVMTKAGGFGNETTLLDVLRFIEEKVSE
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of D-threonate to D-threonate 4-phosphate.  Can also phosphorylate 4-hydroxy-L-threonine, with lower efficiency.
What are the official names of this protein?
D-threonate kinase.
What is the protein family that this protein belongs to?
Belongs to the four-carbon acid sugar kinase family.