PharMolix/UniProtQA huggingface dataset:
Protein: VATA_DAUCA
Sequence: MPSVYGDRLTTFEDSEKESEYGYVRKVSGPVVVADGMGGAAMYELVRVGHDNLIGEIIRLEGDSATIQVYEETAGLMVNDPVLRTHKPLSVELGPGILGNIFDGIQRPLKTIAKRSGDVYIPRGVSVPALDKDTLWEFQPKKIGEGDLLTGGDLYATVFENSLMQHHVALPPDAMGKITYVAPAGQYSLKDTVLELEFQGVKKQFTMLQTWPVRTPRPVASKLAADTPLLTGQRVLDALFPSVLGGTCAIPGAFGCGKTVISQALSKYSNSDTVVYVGCGERGNEMAEVLMDFPQLTMTLPDGREESVMKRTTLVANTSNMPVAAREASIYTGITIAEYFRDMGYNVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLAARLASFYERAGKVKCLGGPERNGSVTIVGAVSPPGGDFSDPVTSATLSIVQVFWGLDKKLAQRKHFPSVNWLISYSKYSTALESFYEKFDSDFIDIRTKAREVLQREDDLNEIVQLVGKDALAETDKITLETAKLLREDYLAQNAFTPYDKFCPFYKSVWMMRNIIHFYNLANQAVERGAGMDGQKISYTLIKHRLGDLFYRLVSQKFEDPAEGEDVLVGKFKKLHDDLTSGFRNLEDETR
What is the function of this protein?
Catalytic subunit of the peripheral V1 complex of vacuolar ATPase.  V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
What are the official names of this protein?
V-type proton ATPase catalytic subunit A, V-ATPase subunit A, V-ATPase 69 kDa subunit, Vacuolar proton pump subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: CYC32_DESVH
Sequence: MRYLVISLFAVSLLMAGSALVGNAADAAKAPKKAIELKHGTSKRMHVMFNHTTHKDIACEQCHHDSPAPDKPYASCTDNDCHATPGPRERDTMSMFVAYHAKDTDRSCYGCHKKMAAQHPEFTGCRPCHMSQQARKEAAASEKK
What is the function of this protein?
Participates in sulfate respiration coupled with phosphorylation by transferring electrons from the enzyme dehydrogenase to ferredoxin (By similarity).  Gamma chain of the formate dehydrogenase (FDH) that catalyzes the reversible two-electron oxidation of formate to carbon dioxide.  The gamma subunit of formate dehydrogenase forms a c-type heme.
What are the official names of this protein?
Cytochrome c3, Formate dehydrogenase 2 subunit gamma (cytochrome c-553), FDH2 subunit gamma (cytochrome c-553), FDH2C.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Periplasm.
Protein: VP1_LYCMC
Sequence: MNTKTLIVVFLVCLLVSEVVLARRCGGRGRRIKIKKIVRKLRPIVRVMKVITRMRTSRPRPRLRPCNSSDLQTTSYQVMQPISPKLKSCPVSLAICNRKCSRRGMKGRCQRRECVCY
What are the official names of this protein?
Venom protein TxLP11, Venom protein VP1.1.
What are the subcellular locations of this protein?
Secreted.
Protein: BIOF_THIDA
Sequence: MTDGALTRLEHGLAALKADHLARRRPLLDGAQGAHVTIDGRRVVSFCSNDYLGLANDPALVAAAHAALDGCGVGAGAAHLISGHHRLHLEFETDFAQWVGKPAALLFSTGYLANLAVVTALISRRGEVFADKLNHASLVDAAKLSGARFSRYRHGDLAQLESRLAASTARDRMIVSDLVFSMDGDVAPVDALLDLAERYDAWLYLDDAHGFGVLNGGRGGLSERARASTRVIYLATLGKAAGVAGASVAADGRVIEWLIQTARPYIYTTAAPPLLAAALRESLRQIAAGAARRGRLQRHVARLRSGLGGLKNAVLADSFTPIQPLIVGANADALTLSQALLQRGILVPAIRTPTVPANTARLRITLSAAHSDADVARLVETVHELA
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: MNME_SHELP
Sequence: MTTDTIVAQATAPGRGGVGIIRVSGDKASDVAMAVLGHLPKVRYADYCDFKAADGAVIDQGIALYFKGPNSFTGEDVLELQGHGGQVVLDMLIKRVMDVDGVRIAKPGEFSEQAFMNDKLDLTQAEAIADLIDATSEQAAKSALNSLQGEFSTQVHELVDQVTNLRLYVEAAIDFPDEEVDFLSDGKIAASLGKIITKLDSVQSSAKQGAIIREGMKVVIAGRPNAGKSSLLNALAGKESAIVTEIAGTTRDVLREHIHLDGMPLHIIDTAGLRDTTDTVEQIGIERAWAEIETADQVLFMVDGTTTDAVDPHDIWPDFIDRLPKNLGVTVVRNKADLTGESLDATDEQGHKVFRLSAKTGSGVDELKAHLKSLMGYQSNLEGGFLARRRHLEALELASSHLALGQEQLEVYQAGELLAEELRMCQLALSEITGKFTSDDLLGKIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PR04_SOLLC
Sequence: MGLFNISLLLTCLMVLAIFHSCEAQNSPQDYLAVHNDARAQVGVGPMSWDANLASRAQNYANSRAGDCNLIHSGAGENLAKGGGDFTGRAAVQLWVSERPDYNYATNQCVGGKMCGHYTQVVWRNSVRLGCGRARCNNGWWFISCNYDPVGNWVGERPY
What is the function of this protein?
Probably involved in the defense reaction of plants against pathogens.
What are the official names of this protein?
Pathogenesis-related leaf protein 4, P4.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
Protein: CEMA_CHLSC
Sequence: MKRAKKAKKEKKESTPLPFPYLASIVLLPWWISLSFKKCFEPWVTHWCNTRQSKFFLNDIQEKGTLERFIELEELFLLDKIIKEYYPDTHIQRLWIRIHKETIQLVKIHNEDHNHIIFCLSTNIISFTILSGYSILGNEELFILNSWVQEFLYNLSDTIKAFSILLFTDLCIGFHSPHGWELMIGSIYKIFGFAHNDQVISGFVSTFPVFLDTFFKYLIFRHLNRVSPSLVVIYDSINEELI
What is the function of this protein?
May be involved in proton extrusion.  Indirectly promotes efficient inorganic carbon uptake into chloroplasts.
What are the official names of this protein?
Chloroplast envelope membrane protein.
What is the protein family that this protein belongs to?
Belongs to the Cema family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: THIK_ECOL5
Sequence: MPFRSNNPLTRDEFLSRFFPQFHPVTTFNRGLSGGSFLIEHQGQRFVVRQPHDPDAPQSAFLRQYRALSQLPACIAPKPHLYLRDWMVVDYLPGEVKTYLPDTNELAGLLYYLHQQPRFGWRITLLPLLELYWQQSDPARRTVGWLRMLKRLRKAREPRLLRLSPLHMDVHAGNLVHSASGLKLIDWEYAGDGDIALELAAVWVENTDQHRQLVNDYATRAKIYPAQLWRQVRRWFPWLLMLKAGWFEYRWRQTGDQQFIRLADDTWRQLLIKQ
What is the function of this protein?
Catalyzes the phosphorylation of thiamine to thiamine phosphate.
What are the official names of this protein?
Thiamine kinase.
What is the protein family that this protein belongs to?
Belongs to the thiamine kinase family.
Protein: QUEF_MICAN
Sequence: MVQSSEKIEVKYGEREIAEGTLITFPNPRPGRNYDIQITLPEYTCKCPFSGYPDFATIYLSYVPDQKVMELKAIKLYINSYRDRYISHEEAINQILDDLVAACEPLQMKVKGDFHPRGNVHTVVEVMYKKE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH10_YERE8
Sequence: MKIRPLHDRVIVKRKEVESKSAGGIVLTGTAAGKSTRGEVLAVGNGRILDNGEIKPLDVKVGDIVIFNDGYGVKSEKIDHEEVLIMSESDILAIVEA
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPR_SIVTN
Sequence: MEQAPNDNGPQREPYTEWLLDILEEIKQEAVKHFPRPILQGVGNWVFTIYGDSWEGVQELIKILQRALFTHYRHGCIHSRIGS
What is the function of this protein?
Stimulates gene expression driven by the HIV-2 LTR.  Prevents infected cells from undergoing mitosis and proliferating, by inducing arrest or delay in the G2 phase of the cell cycle.  Cell cycle arrest creates a favorable environment for maximizing viral expression and production (By similarity).
What are the official names of this protein?
Protein Vpr, R ORF protein, Viral protein R.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: ATPL_PROM1
Sequence: MDSITTAASVVAAGLAVGLGAIGPGIGQGSAAQGAVEGIARQPEAEGKIRGTLLLSFAFMESLTIYGLVVALVLLFANPFAG
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: RS8_DESHY
Sequence: MAMSDPIADFLTRIRNAGMVYHDKVEVPASNVKKAIAEILKEEGFIKDVEYISDNKQGVIRCYLKYGQNRERVITGLKRISRPGLRVYAKKDEVPKVLGGLGVAILSTSKGLMTDKRARQEGLGGEVLCYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: CRTM_STAAU
Sequence: MTMMDMNFKYCHKIMKKHSKSFSYAFDLLPEDQRKAVWAIYAVCRKIDDSIDVYGDIQFLNQIKEDIQSIEKYPYEYHHFQSDRRIMMALQHVAQHKNIAFQSFYNLIDTVYKDQHFTMFETDAELFGYCYGVAGTVGEVLTPILSDHETHQTYDVARRLGESLQLINILRDVGEDFENERIYFSKQRLKQYEVDIAEVYQNGVNNHYIDLWEYYAAIAEKDFRDVMDQIKVFSIEAQPIIELAARIYIEILDEVRQANYTLHERVFVEKRKKAKLFHEINSKYHRI
What is the function of this protein?
Involved in the biosynthesis of the yellow-orange carotenoid staphyloxanthin, which plays a role in the virulence via its protective function against oxidative stress.  Catalyzes the head-to-head condensation of two molecules of farnesyl diphosphate (FPP) into the colorless C(30) carotenoid 4,4'-diapophytoene (dehydrosqualene).
What are the official names of this protein?
4,4'-diapophytoene synthase, DAP synthase, C30 carotenoid synthase, Dehydrosqualene synthase.
What is the protein family that this protein belongs to?
Belongs to the phytoene/squalene synthase family. CrtM subfamily.
Protein: RL33_ECO24
Sequence: MAKGIREKIKLVSSAGTGHFYTTTKNKRTKPEKLELKKFDPVVRQHVIYKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: UBP26_ARATH
Sequence: MSRPNTRNKNKRQRPDAVDSSSQILRKIHEANDVTDDDINQLFMIWKPVCQGCRVNTRDNPNCFCGLVPPLNGSRKSGLWQKTSEIIQSLGPDPTLDRRDSESTPAGLTNLGATCYANSILQCLYMNTAFREGVFSVEVHVLKQNPVLDQIARLFAQLHASQKSFVDSDAFVKTLELDNGVQQDTHEFLTLLLSLLERCLLHSGVKAKTIVQDLFSGSVSHVTTCSKCGRDSEASSKMEDFYALELNVKGLKSLDASLNDYLSLEQLNGDNQYFCGSCNARVDATRCIKLRTLPPVITFQLKRCIFLPKTTAKKKITSSFSFPQVLDMGSRLAESSQNKLTYDLSAVLIHKGSAVNSGHYVAHIKDEKTGLWWEFDDEHVSELGKRPCNEASSSTPQSESNGTASSGNITDGIQSGSSDCRSAIKSEVFSSSDAYMLMYSLRCDKQENQEGQKENPIDITKGEVKQLKGGYLPKHLSEWINNMNAVFLESCKQYNLRKEKELNALTERRQEVRTILSEAAVQSLEEQYFWISTDWLRLWADTTLPPALDNTPLLCSHGKVHASKVNCMKRISELAWIKLESKFNGGPKLGKGDYCRDCLMDGARMVVSSDSYRDRRTFMKSIANDVLSGKCEDGMYYISRAWLQQWIKRKNLDAPTEADAGPTNAITCNHGELMPEQAPGAKRVVVPENFWSFLFEDALKVMSEDTLDCTCFPVDSSQCCHCTEVLSEVACFEDSLRTLKVKQRQNHEKLATGKGIPLTPQSRYFLLPSPWLVQWRIYINMTGKNSSSAPEPERLDGVINTLKCKKHTRLLERLPELVCRRGSYFQKNPSTDKLTIIPELDWKYFCDEWGGLMENGISAFIEVGNTDQSSSPDVIDLEKDSSPDDNMDVDAQQLILRASPEICEECIGERESCELMQKLSYSEGDVFVCFVRGKEAPKAMLEASDSSFEVDRRTSKRSRRTNYGNLTSLKVSATTTVYQLKMMIWELLGVMKENQELHKGSKVIDQESATLADMNIFPGDRLWVRDTEMHEHRDIADELCEKKPGAQDIEEGFRGTLLTGNISSEAC
What is the function of this protein?
Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin.  Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.  Deubiquitinates H2BK143ub1 of histone H2B.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 26, Deubiquitinating enzyme 26, AtUBP26, Ubiquitin thioesterase 26, Ubiquitin-specific-processing protease 26.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y027_SYNSC
Sequence: MAGFGLPNFGQLTEAFKKAQEIQQNAQALQDELDGMEIEGKSSDGRASVWLSGNQQPLRVRLDPALLQEGQQASETATLEALQAAYEQSTATMKGRMEELTGGLNLNLPGMGG
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Syncc9605_0027.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: SYS_STRPB
Sequence: MLDLKRIRTDFDTVAAKLKNRGVSEDTLTHLKELDEKRRTLLVQSEELKAERNIASAAIAQAKRQKEDATQQIADMQKVSADIKTIDNQLVAIDQQVTDIITVLPNTPHDSVPVGADEEDNVEIRRWGTPRDFNFEVKAHWDLGEDLDILDWERGAKVTGARFLFYKNLGARLERALYNFMLDEHIKEGYQEIITPYMVNHDSMFGTGQYPKFKEDTFELADTNFVLIPTAEVPLTNYYRGEILDGKELPIYFTAMSPSFRSEAGSAGRDTRGLIRLHQFHKVEMVKFAKPEESYQELEKMTANAENILQKLGLPYRVISLCTGDMGFSAAKTYDLEVWIPAQNTYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTVAAILENYQNEDGSVTIPEVLRPYMGGETVISPK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASPG_SPOFR
Sequence: EKNMPIVITTWSFTNASQKAWEVLKDEGKALDAVEQGGIVCENEQCDRTVGYGGSPDEDGETTLDAFIMDGSTMNVGAVAALRRIKSAISVARHVMEYTTHSFLAGELATKFAVEMGFKEESLSTDESRELWSKWRFEKQCQPNFRKNVKPDPRKHCGPYHKKRNFVDYIHPEVFVVDQYNHDTIGMVAVDSKGDVAAGTSTNGAKFKIPGRVGDSPIPGAGAYADNTVGGAAATGNGDTMMRFLPSFLAVEEMRRGASPANAAKTAIKRISAHHPDFMGAVIALSKNGQYGAACNGIETFPFVVQDKTRKTFEVVTIKC
What is the function of this protein?
Cleaves the GlcNAc-Asn bond which joins oligosaccharides to the peptide of asparagine-linked glycoproteins.
What are the official names of this protein?
N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase, Aspartylglucosaminidase, AGA, Glycosylasparaginase, N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase.
What is the protein family that this protein belongs to?
Belongs to the Ntn-hydrolase family.
What are the subcellular locations of this protein?
Lysosome.
Protein: CLPP_AZOBR
Sequence: MYDFEPKMNALVPMVIEQTNRGERGYDIYSRLLKERIIFLIGGVNDAVASLICSQLLFLESENPSKDIALYINSPGGYVSAGLAIYDTMQYIRPQVSTVCMGQAASMGSLLLAAGAPGKRFSLPNSRIMIHQPSGGAQGQASDIEIQAQEILKLRSRLNDIYVKHTGQSLDTIEAXMERDKFMSPEEAKAFGLIDEVVEKRPGSIGDGAA
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y01K_BPT4
Sequence: MKTFKEFIKEDMVAGDSGGNPENISIGTTSGAVVNKGPEQIPKKKKEESKEKEE
What are the official names of this protein?
Uncharacterized 5.9 kDa protein in Gp58-sp intergenic region.
Protein: Y2265_ARATH
Sequence: MVVEAYVKQTEALEKKNRIVELMLEREHASSVKSVLETLNGLPGVRMWSPFHKTSIDHLIADEASRQGFIAFPRAEHKRTGEEDLIWDPNAVDDFCRGDMHKWLEEMPNYCYYNCAGEGIGFARQRMALFIYALQRAYLPFEMKKVVVQTREDIESSMKLKASNAIFYMNFKAYGGPQCRGIVRKQVIED
What are the official names of this protein?
UPF0725 protein At2g20625.
What is the protein family that this protein belongs to?
Belongs to the UPF0725 (EMB2204) family.
Protein: KGUA_NITMU
Sequence: MTTTPGTLYIISAPSGAGKTSLVKALLQTGIDLSLSISYTSRQPRPEEMDGRDYHFVTRQVFEQKLQEDEFLESAELYGNFYGTSKKWINETMTSGRDILLEIDSQGARQVRAVFPVAVGIFVLPPSLEVLEMRLRQRAQDSLEAISRRLAAAREELSHAGEYNYIIINDKLDRALQDLKCIIQAERLKTAKQLVRHHGLLAQLTRTSVL
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4E_SULIL
Sequence: MAHITRFETPWFLVISKKQYKWTVRPNAGPHPIEKSIPLAVVIRDYLKLAETVREAKHIIFDGKVLVDGKVRKDYKYPVGLMDIVSIPSADLYFRVIPDNVRFMRLSKISADEAHYKYVRIMNKTTVKGGSIQLNLEDGRNILVDKETAKSFKTLMTLKIELPSQNIVDSFIISEGSYAIFVGGKNVGIHGVVKNINLSKFKSRKYSVITLESKDGNTYQTNLMNVMSIGREKSDMRVD
What are the official names of this protein?
30S ribosomal protein S4e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS4 family.
Protein: MASZ_AGRRK
Sequence: MSRIEKNGLQIEPVLYDFLVKEALPGSGVDADTFFAGFSAIVHDLAPKNRELLAKRDRMQAAIDDWYRKNGAPVDLAAYEAFLREIGYIIPEGPAFTVSTANVDTEIASIAGPQLVVPVMNARYALNAANARWGSLYDALYGTDAIPETDGAEKGKGYNPKRGEKVIAWVRDFLDAAVPLSDASWKDVAGFAVKGGVLAIATKSGTVALTDERHFAGYLGDVAAPSHILLKNNGIHIEIVLDPSTDIGKVDPAHISDVRLESAITTIMDCEDSIAAVDAEDKAEVYRNWLGLMKGDLTEEVAKGGKTFTRRLNPDVTYTAPDGASFELHCRSLMLIRNVGHLMTNPAILDRDGNEVPEGIMDAMITGLIALYDVGPKGRRKNSRAGSMYVVKPKMHGPEEVAFAVEIFSRVEDVLGMPRNTIKMGIMDEERRTTVNLKEAIRAASERVVFINTGFLDRTGDEIHTSMEAGPMIRKGDMKQAAWIAAYENWNVDIGLECGLSGHAQIGKGMWAMPDLMAAMLEQKIAHPKAGANTAWVPSPTAATLHATHYHKVNVANVQQTLKSRVRAKLSDILSVPVASRPNWTPEEIQHEIDNNCQGILGYVVRWVDQGVGCSKVPDINNIGLMEDRATLRISAQHMANWLHHKVITEAQIVETMKRMATVVDQQNAGDPLYIAMAGNFDGSVAFQAALELVLKGREQPNGYTEPVLHRRRIELKAKQAV
What is the function of this protein?
Involved in the glycolate utilization.  Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
What are the official names of this protein?
Malate synthase G.
What is the protein family that this protein belongs to?
Belongs to the malate synthase family. GlcB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CREC_CAEEL
Sequence: MTSLFDALSRSNDRLPSPNFLPEDFLELLKSNDFDTKLTTLIRAATIAKREEDWFHKFQKKGELFKCIDKIICDDRWELQHQCIKFLVEAMPTFGSATEYCMCFVMPNLIPKLVSNKVTVRKITHQAIATFLRLKPEALQSFLKMLSNFMPNCNSKSELITELHHILIPELVKSNWTCLVENFTTESNIQGCEDQAGVLMKKLHYFIGNEFWQKIITNLSPEKREVLEQITANVQVEHTESKAGSGVLRASAKPQSGGERRLRFGIVPSLVCALIAEDTDANQRISGLEKMKQVVDQITPEEIARLVPHLHSYLLMLSNVLEDLNFKVVVLALDIVRATGHHLKGHMEAHIQQFVNLVAKHFGNQKSVIKQIIMMTFMELFQNINPKTVGGCLRVFLENKNSRVREEVINIYTASLMTISPSKFNLQPLVNILVPMFHDVKKRVRLAAFEQLSVLAYLLNGKTEIIMKPVRDFEQDQNSRGLTEAVTARIRRQVLPRIRYDGLIEYSTPPMMDSFDLAEAEMSLPSNADLSWIVSNGGVEPDPFERTMSPISLAGNLATIRRNRVIQQQGQAEKPSFSLPQQPAQQASHQAQRLPNGIEKSHETSENSSLDIGQRIVMTRMKSDDSFVRRQGSAASNPNSSTSSWEAPKRPPISPSEKSSISATKKEVNNNHIVKKGNLKSMRARSDTNLSEDHGEEEMENDPPRSFDDRPAKASGQYSFQDFDAAIVPSSMGKKSISHHSLPITSHPPLKHAISQPQKRINNNGTFLRSGQGQRTKSVSKPHRELTAVSKTYSLLDTSNMSVNQALKKMSSDEWADKVDGLNMISTLSETQPRMVADNLKEVIIAILNECKNLRSSVSRVAIVTIGTVAQNLNSKIDSEMEKICAVLLSKSGDVSNAFIRDDATDSLNKLVKAATAGKALQGIILAGAKSKNNTIRSSCANFVYDIITIQGSSAILNNQNALSNVLPVLLQFSRDQSPQVRNPGKQSLCFLSKDPNFDRLMRKNALESEIKAVKDVLANVEKRGGVDSLESTANLSGSLSRIGSTRRVQKKLPDSLQLDLDEIRTELLAAGWERRLTGLQRFEEMCGHASKAVASDTRLIEAFISRLGDTNGKVASCAMETYISTMGSMAKLYSTESNLKAVMNQLAHALTAHLSSKSEEHKHLARTCIQHTIRSIEPVSLLPAMTSATKKSNVKQRPFILTQYCELSKLAYKSKPKQVEVMALPLLWDSVKNSAPDVDNKKATQYLAKTLAKLIGEKQLLDLATSELDPNRKKQLDALIR
What is the function of this protein?
Required for normal structure and function of sensory cilia on amphid neurons, especially for the formation of distal ciliary structures, but is less important for normal assembly of middle and basal ciliary structures.  Plays a role in the organization of axoneme microtubule bundles in sensory cilia.  Required for normal structure and function of the ASER neuron that mediates attraction to NaCl.  Required for normal chemotaxis to NaCl (PubMed:18245347, PubMed:26378256).  Required for normal avoidance response to high osmolarity.  In contrast, is not required for normal chemotaxis to isoamyl alcohol.  Does not play a role in intraflagella transport (IFT) (PubMed:18245347).  Promotes dauer formation in response to pheromones such as the ascarosides ascr#2, ascr#3, ascr#5, ascr#8 and icas#9 (PubMed:26976437).
What are the official names of this protein?
Crescerin-like protein che-12.
What is the protein family that this protein belongs to?
Belongs to the Crescerin family.
What are the subcellular locations of this protein?
Cell projection, cilium. Perikaryon. Cell projection, dendrite. Note=Detected in neuronal cell bodies, and to a lesser extent in dendrites. Detected in ASER cilia (PubMed:18245347, PubMed:26378256). Requires the intraflagella transport (IFT) machinery for normal location in cilia, but does not play a role in IFT itself (PubMed:18245347).
Protein: PMD_HALVD
Sequence: MKATAKAHPIQGLVKYHGMRDTERRMPYHDSISVCTAPSHTQTTVEFRPDADEDVYVIGGEEVEGRGAERIQAVVDRVRELAGFDHRVRLESENSFPSNIGFGSSASGFAAAAMALAEAADLDMTRPEVSTIARRGSASAARAVTGAFSHLYSGMNDTDCRSERIETDLEDDLRIVAAHVPAYKETEQAHAEAADSHMFQARMAHIHAQIDDMRDALYDGDFDAAFELAEHDSLSLAATTMTGPAGWVYWQPRTIAVFNAVRKLRNEEDVPVYFSTDTGASVYINTTEEHVDRVEEAVADCGVETDVWGVGGPAEVLDESEALF
What is the function of this protein?
Catalyzes the decarboxylation of mevalonate 5-phosphate (MVAP) to isopentenyl phosphate (IP).  Functions in an alternate mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
What are the official names of this protein?
Phosphomevalonate decarboxylase, PMD, Mevalonate monophosphate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the phosphomevalonate decarboxylase family.
Protein: WAT1_SCHPO
Sequence: MSVQYPPQHSVLLVSSGYDHTIRFWEALSGICSRTIQHADSQVNRLCISPDKKFLAAAGNPHVRLYDINTSSQMPLMTFEGHTNNVTAIAFHCDGKWLATSSEDGTVKVWDMRAPSVQRNYDHKSPVNDLLIHPNQGELLSCDQSGRVRAWDLGENSCTHELIPEEDVPMSSITVGSDGSMLIAGNNKGNCYVWRMLNHQGASLLQPVVKFQAHQRYITRCVLSPDVKHLATCSADATVNIWSTEDMSFMLERRLQGHQRWVWDCAFSADSTYLVTASSDHVARLWELSSGETIRQYSGHHKAAVCVALNDYQI
What is the function of this protein?
component of both TORC1 and TORC2, which regulate multiple cellular processes to control cell growth in response to environmental signals.  Nutrient limitation and environmental stress signals cause inactivation of TORC1.  Active TORC1 positively controls cell growth and ribosome biogenesis by regulating ribosomal protein gene expression.  TORC1 negatively controls G1 cell-cycle arrest, sexual development and amino acid uptake.  Represses mating, meiosis and sporulation efficiency by interfering with the functions of the transcription factor ste11 and the meiosis-promoting RNA-binding protein mei2.  TORC2 is required for cell survival under various stress conditions.  TORC2 positively controls G1 cell-cycle arrest, sexual development and amino acid uptake.  Positively regulates amino acid uptake through the control of expression of amino acid permeases (PubMed:17046992, PubMed:18076573, PubMed:17261596).  May play a role in mRNA maturation as a coupling protein between splicing and synthesis and/or stabilization.
What are the official names of this protein?
Target of rapamycin complex subunit wat1, TORC subunit wat1, WD repeat-containing protein pop3.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LST8 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RS5_HELPY
Sequence: MEEINREEFQEVVVNIGRVTKVVKGGRRFRFNALVVVGNKNGLVGFGLGKAKEVPDAIKKAVDDAFKNLIHVTIKGTTIAHDIEHKYNASRILLKPASEGTGVIAGGSTRPIVELAGIKDILTKSLGSNNPYNVVRATFDALAKIKA
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.