PharMolix/UniProtQA huggingface dataset:
Protein: DTD2_DANRE
Sequence: MKARVVLQQCLHARLQVKPPDEESEAEWVEVNRGMVIYICFFKGATEDLIPKMVNTLLNVKLCETESGKFTSVLQLPGSVLIVPQATLGGKPKGRGMQYHGNIGKDEGLKLYETFVSLCQSELSSCKNSDILTEVKHGTYGNRQVLKLDTNGPYTHLMEF
What is the function of this protein?
Deacylates mischarged D-aminoacyl-tRNAs (By similarity).  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS (By similarity).  Probably acts by rejecting L-amino acids from its binding site rather than specific recognition of D-amino acids (By similarity).  Catalyzes the hydrolysis of D-tyrosyl-tRNA(Tyr), has no activity on correctly charged L-tyrosyl-tRNA(Tyr) (By similarity).  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.  In contrast to DTD1, deacylates L-Ala mischarged on tRNA(Thr)(G4. U69) by alanine-tRNA ligase AARS (PubMed:29410408).  Can deacylate L-Ala due to a relaxed specificity for substrate chirality caused by the trans conformation of the Gly-Pro motif in the active site (PubMed:29410408).  Also hydrolyzes correctly charged, achiral, glycyl-tRNA(Gly) in vitro, although in vivo eef1a1a/EF-Tu may protect cognate achiral glycyl-tRNA(Gly) from DTD2-mediated deacetylation (By similarity).
What are the official names of this protein?
D-aminoacyl-tRNA deacylase 2, Animalia-specific tRNA deacylase, ATD, D-tyrosyl-tRNA deacylase 2, L-alanyl-tRNA deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALDOB_CHICK
Sequence: MTHQFPALSPEQKKALSDIAQRIVASGKGILAADESVGTMGNRLQRINVENTEENRRAFREILFSSDASISKSIGGVILFHETLYQKDSSGKPFPAIIKEKGMVVGIKLDAGTAPLAGTNGETTIQGLDKLAERCAQYKKDGADFGKWRAVLKISSTTPSQLAIQENANTLARYASICQQNGLVPIVEPEVLPDGDHDLQRCQYVTEKVLAAVYKALNDHHVYLEGTLLKPNMVTAGHSCPKKYTPQDVAVATVTTLLRTVPAAVPGICFLSGGQSEEEASLNLNAMNQSPLPKPWKLTFSYGRALQASALAAWLGKSENKKAAQEAFCKRAQINSLACRGQYVTSGKTDTAATQSLFTASYTY
What are the official names of this protein?
Fructose-bisphosphate aldolase B, Liver-type aldolase.
What is the protein family that this protein belongs to?
Belongs to the class I fructose-bisphosphate aldolase family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite.
Protein: RL3_STAAB
Sequence: MTKGILGRKIGMTQVFGENGELIPVTVVEAKENVVLQKKTVEVDGYNAIQVGFEDKKAYKKDAKSNKYANKPAEGHAKKADAAPKRFIREFRNVDVDAYEVGQEVSVDTFVAGDVIDVTGVSKGKGFQGAIKRHGQSRGPMSHGSHFHRAPGSVGMASDASRVFKGQKMPGRMGGNTVTVQNLEVVQVDTENKVILVKGNVPGPKKGLVEIRTSIKKGNK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: RL19E_METVA
Sequence: MDVSTQRRIAAAVLDCGIDRVWVDPENLEKVKMAITKDDIRLLINDGIIVKKQEKGISSARKKEVQEQKRKGKRKGPGSRRGAKGARTPKKEKWMNTIRPLRTLLKELRENEKIERSSYRKLYRMAKGGAFRSRNHMKLYMKEHGILAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L19e, ORF E.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL19 family.
Protein: AOC1_PIG
Sequence: MGRGTLALGWAGAALLLLQMLAAAERSPRTPGGKAGVFADLSAQELKAVHSFLWSQKELKLEPSGTLTMAKNSVFLIEMLLPKKQHVLKFLDKGHRRPVREARAVIFFGAQEQPNVTEFAVGPLPTPRYMRDLPPRPGHQVSWASRPISKAEYALLSHKLQEATQPLRQFFRRTTGSSFGDCHEQCLTFTDVAPRGLASGQRRTWFILQRQMPGYFLHPTGLELLVDHGSTNAQDWTVEQVWYNGKFYRSPEELAQKYNDGEVDVVILEDPLAKGKDGESLPEPALFSFYQPRGDFAVTMHGPHVVQPQGPRYSLEGNRVMYGGWSFAFRLRSSSGLQILDVHFGGERIAYEVSVQEAVALYGGHTPAGMQTKYIDVGWGLGSVTHELAPDIDCPETATFLDALHHYDADGPVLYPRALCLFEMPTGVPLRRHFNSNFSGGFNFYAGLKGQVLVLRTTSTVYNYDYIWDFIFYPNGVMEAKMHATGYVHATFYTPEGLRYGTRLHTHLIGNMHTHLVNYRVDLDVAGTTNSFQTLQMELENITNPWSPRHRLVQPTLKQTRYSRERQAAFRFGQPLPKYLLITSPKENPWGHTRSYRLQLHSMADQVLPPGWQEERAVTWARYPLAVTRYRESELSSSSIYNQNDPWDPPVVFEEFLRNNENIEDEDLVAWVTVGFLHIPHSEDIPNTATPGNSVGFLLRPFNFFPEDPALASRDLVVVWPLENGSTYAQRWIPEEDQSCLKPPPFSYNGSYRPV
What is the function of this protein?
Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis.
What are the official names of this protein?
Amiloride-sensitive amine oxidase [copper-containing], DAO, Diamine oxidase, Amiloride-binding protein 1, Amine oxidase copper domain-containing protein 1, Histaminase.
What is the protein family that this protein belongs to?
Belongs to the copper/topaquinone oxidase family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: ARP21_PONAB
Sequence: MSEQGDLNQAIAEEGGTEQETATPENGIVKSESLDEEEKLELQRRLEAQNQERRKSKSGAGKGKLTRSLAVCEESSARPGGESLQDQTL
What is the function of this protein?
May act as a competitive inhibitor of calmodulin-dependent enzymes such as calcineurin in neurons.
What are the official names of this protein?
cAMP-regulated phosphoprotein 21, ARPP-21.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARPA_ECOLI
Sequence: MITRIPRSSFSANINNTAQTNEHQTLSELFYKELEDKFSGKELATPLLKSFSENCRQNGRHIFSNKDFVIKFSTSVLQADKKEITIINKNENTTLTQTIAPIFEKYLMEILPQRSDTLDKQELNLKSDRKEKEFPRIKLNGQCYFPGRPQNRIVCRHIAAQYINDIYQNVDYKPHQDDYSSAEKFLTHFNKKCKNQTLALVSSRPEGRCVAACGDFGLVMKAYFDKMESNGISVMAAILLVDNHALTVRLRIKNTTEGCTHYVVSVYDPNVTNDKIRIMSESKENIKHYSLMDFMNVDYSLLKWSNDHVINQSVAIIPALPKEQLLMLKGSVDEITPPLSPATMNLLMAIGQNHQLTQLMIQLQKMPELHRTEMLTAYNSINLPGLYLAINYGNADIVETIFNSLSETGYEGLLSKKNLMHILEAKDKNGFSGLFLAISRKDKNVVTSILNALPKLAATHHLDNEQVYKFLSAKNRTSSHVLYHVMANGDADMLKIVLNALPLLIRTCHLTKEQVLDLLKAKDFYGCPGLYLAMQNGHSDIVKVILEALPSLAQEINISASDIVDLLTAKSLARDTGLFMAMQRGHMNVINTIFNALPTLFNTFKFDKKNMKPLLLANNSNEYPGLFSAIQHKQQNVVETVYLALSDHARLFGFTAEDIMDFWQHKAPQKYSAFELAFEFGHRVIAELILNTLNKMAESFGFTDNPRYIAEKNYMEALLKKASPHTVR
What are the official names of this protein?
Ankyrin repeat protein A, Ankyrin-like regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the Toxin_15 family.
Protein: NRDI_MYCBO
Sequence: MDIAGRSLVYFSSVSENTHRFVQKLGIPATRIPLHGRIEVDEPYVLILPTYGGGRANPGLDAGGYVPKQVIAFLNNDHNRAQLRGVIAAGNTNFGAEFCYAGDVVSRKCSVPYLYRFELMGTEDDVAAVRTGLAEFWKEQTCHQPSLQSL
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: ST7_DROPS
Sequence: MWDSSMFLSTLTPKFYVALTGTSSLISGLILIFEWWYFRKYGTSFIEQVSINHISPWINGNDAQSDSSNGSGSSTSSGSSSSSNGGGGGGGGGAGGGGPGAGGGTNSTTTTGTQMPECKVWRNPLNLFRGAEYQRFFWATSKEPLTYYDMNLSAQDHQTFFTCEGDARKEEYEIMQTAWRERNPMQRIKSAHNALEINAECAPAYILLAEEEAMTIMEAEKILKTALKVAEINYRKSQATQHQGAIADGMHRRDTNVLIYIKRRLAMCARKLGKLKEAAKMFRDLTKEIPSIMSVLNIHENLIETLLEMQAYADCHAILAKYDDISLPKSATICYTAALLKARAVADKFSPDIASKRGLSPAEMSAVEAIHRAVEFNPHVPKYLLETKPLILPPEHILKRGDSEALAYAFFHLKHWKQVEGALNLLHCTWEGTFRMLPYPLERGHLFYPYPTCTECADRELLPAFHEVSVYPKKELPFFILFTAGLCSFTALLALLTHQYPEPMGLLAQTVLTWISYPFQLLKERVEAFWPCNLLQQLSRV
What are the official names of this protein?
Protein ST7 homolog.
What is the protein family that this protein belongs to?
Belongs to the ST7 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: POTA_ECO57
Sequence: MGQSKKLNKQPSSLSPLVQLAGIRKCFDGKEVIPQLDLTINNGEFLTLLGPSGCGKTTVLRLIAGLETVDSGRIMLDNEDITHVPAENRYVNTVFQSYALFPHMTVFENVAFGLRMQKTPAAEITPRVMEALRMVQLETFAQRKPHQLSGGQQQRVAIARAVVNKPRLLLLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGTPREIYEEPKNLFVAGFIGEINMFNATVIERLDEQRVRANVEGRECNIYVNFAVEPGQKLHVLLRPEDLRVEEINDDNHAEGLIGYVRERNYKGMTLESVVELENGKMVMVSEFFNEDDPDFDHSLDQKMAINWVESWEVVLADEEHK
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GRPE_KLULA
Sequence: MRPSTRFLRSVTRTVPIGFRSTTVPFVSSTLRSSAATSNQFSARFSGVRFYADEAKKEEPKDENDAAAAEEDANLTEEQKKIKDLETKLDAKTKEASEFKDRLLRSVADFRNLQEVTKKDIQKAKDFALQKFAKDLLESVDNFGHALNAFKPETLEQSQELSDLYTGVKMTRDVFEKTLKKHGIEQLNPIGESFDPNKHEATFELPQPDKEPGTVFHVQQIGYTLNDRVIRPAKVGIVKDNEN
What is the function of this protein?
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.  Seems to control the nucleotide-dependent binding of SSC1 to substrate proteins (By similarity).
What are the official names of this protein?
GrpE protein homolog, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: DNAJ_SHEPA
Sequence: MSKRDYYEVLGVGRDTSEREIKKAYKRLAMKFHPDRNPGDKEAEANFKEVKEAYEILTDSDKKAAYDQFGHAGVDPNRGGGGYGGSADFGDVFGDVFGDIFGGGRRGGQRQAARGSDLRYNLELSLEEAVRGLTKELRIPTLAACDSCDGSGAKKGSSPTTCGTCHGQGQVQMRQGFFAVQQACPTCHGRGKIIKDPCNKCHGEGRVEKSKTLSVKIPAGVDTGDRIRLSGEGEAGEYGAPPGDLYVQVSVREHAIFQRDGNNLYCEVPISFSKAALGGEIEVPTLDGKVNLKIPAETQTGRMFRMRGKGVKSVRSHAVGDLLCKVVMETPVNLNERQKELLREFEDTLTGQSKKHSPKAEGFFDGVKKFFQDLNS
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YRHD_BACSU
Sequence: MATPITTIKKETKTAEQIKLEKIEELKELLAENEDAVSKTMTLMNELNDLGIFDAATSMLRAKEDIAKIALGQVSREPVTNLINTMMAAGGALTKADPEFTAKLLESVMAGTEQAQSFLKEDKKVGILDLLKAMNDPDINRAVGFGLQFLKGMGKELREQ
What are the official names of this protein?
Uncharacterized protein YrhD.
What is the protein family that this protein belongs to?
To A.fulgidus AF1717.
Protein: AAMAT_AMAFU
Sequence: MSDINATRLPIWGIGCNPSVGDEVTALLTSGEA
What is the function of this protein?
Major toxin belonging to the bicyclic octapeptides amatoxins that acts by binding non-competitively to RNA polymerase II and greatly slowing the elongation of transcripts from target promoters (PubMed:24613547).
What are the official names of this protein?
Alpha-amanitin proprotein.
What is the protein family that this protein belongs to?
Belongs to the MSDIN fungal toxin family.
Protein: NUOL_MYCTU
Sequence: MTTSLGTHYTWLLVALPLAGAAILLFGGRRTDAWGHLLGCAAALAAFGVGAMLLADMLGRDGLERAIHQQVFTWIPAGGLQVDFGLQIDQLSMCFVLLISGVGSLIHIYSVGYMAEDPDRRRFFGYLNLFLASMLLLVVADNYVLLYVGWEGVGLASYLLIGFWYHKPSAATAAKKAFVMNRVGDAGLAVGMFLTFSTFGTLSYAGVFAGVPAASRAVLTAIGLLMLLGACAKSAQVPLQAWLGDAMEGPTPVSALIHAATMVTAGVYLIVRSGPLYNLAPTAQLAVVIVGAVTLLFGAIIGCAKDDIKRALAASTISQIGYMVLAAGLGPAGYAFAIMHLLTHGFFKAGLFLGSGAVIHAMHEEQDMRRYGGLRAALPVTFATFGLAYLAIIGVPPFAGFFSKDAIIEAALGAGGIRGSLLGGAALLGAGVTAFYMTRVMLMTFFGEKRWTPGAHPHEAPAVMTWPMILLAVGSVFSGGLLAVGGTLRHWLQPVVGSHEEATHALPTWVATTLALGVVAVGIAVAYRMYGTAPIPRVAPVRVSALTAAARADLYGDAFNEEVFMRPGAQLTNAVVAVDDAGVDGSVNALATLVSQTSNRLRQMQTGFARNYALSMLVGAVLVAAALLVVQLW
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit L, NADH dehydrogenase I subunit L, NDH-1 subunit L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PDXD1_HUMAN
Sequence: MDASLEKIADPTLAEMGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQGSGQDMVSILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSDTTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSAAARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVANAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPGPWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHACQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGRERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVACIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPEGENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIEENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKGRTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSETSSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQVEGPESLR
What are the official names of this protein?
Pyridoxal-dependent decarboxylase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
Protein: ISK7_MOUSE
Sequence: MKLVGGLLLLFAATYVCNCSEVTSHPSATVDCDIYKKYPVVAIPCPIVNIPVCGSDYITYGNKCKLCTEILRSNGKIQFLHEGHC
What is the function of this protein?
Probable serine protease inhibitor.
What are the official names of this protein?
Serine protease inhibitor Kazal-type 7, Esophagus cancer-related gene 2 protein, ECRG-2.
What are the subcellular locations of this protein?
Secreted.
Protein: ADDB_CLOBH
Sequence: MSLRFIYGRAGSGKSQYCLNSIKNRIEEDIDRPLILLVPEQFSFQAEKNLIEVLDEKTGFKTQVLSFKRMAYRVFNEVGGITAKHMNESGKSMLLYNIIEDNKNNLKVFKKAAKRQGFITTISDIITEFKRYNITPEIILNNLENIEGDNLKYKMEDLALIFSQFETRLHKNYIDNEDDLTILAEKLNKSKQFDNAEIWIDEFSSFSPQEYSVLEKLLLKSYRINITLCTDYLNQGRFVDTTDVFSPIKNTENKLLQIIEDNNIKLDKPIALNCDPCARFKNSAELQHLEKNMFSFPYKEYKNETKDICMLKTLNQFTEIENTAKDIIKLCIDKGCRFKDIAVITGDLEGYENIISSVFLQYNIPFFIDKKREINNNPIIVLILSALEVLSKNWTYESVFRYLKTGLLDINNEEMDILENYVLANGIKGYQWTNDKPWEHKFFSNYELEDQVEKELLAKINDIRYKAMEPIVTLNKNFKSIDKAKEFCEVLYEFLCNINLPDKIQNMIEDFKVEGEIEKASEYNQIWNIVMEVLDQIVEVIGEEKISLKEFFKILQTGLSEYEIGLIPPTLDQVMVGSITRLRSHNINTLYIVGVNDGIFPSPLKEEGILSDDDRKFLGDKGLEIAKDTKSIAFEEQFLVYSTLTTPSKYLRLSYPIADGEGKTLRPSIIISRIKKIFTNICEENDIVKLNGEEEELKNISSAKPTFNYLISNLRKDVEGAKIDNIWGDTYKWYLENEFWIEKLNRLIKGFDYTNQSKYIETKKIRNLYGKPLKISVSRVEKFSQCPFAYFVQYGLKAKDRKIFNLSYPDLGIFMHSILEKFSHELEKQGLEWDTMDLNWAEEEIDKLINEELDNKSLDILNSSKRYEYVTKSVKKILKRSIWLIGEHIKRGNFKPSYYELSFDIDGDYPPIAMELHSGEVVNLIGRVDRVDLLQKDGATYLKIIDYKSGAKEFKLSDVYYGLQLQLLIYLDAILTELAERSGINGEPGALLYLKLDDPIVKNTVDMSDEEIEKSIIKNLKMKGLILNDPNVIRDMDNIISGISDIIPVMVKKDGGVSEGRSSVATKEEFETLRKYVRYTIIEICEEMLEGNIEIKPYKKKDGSSCDYCIYSSVCKFDTNIRGNKYNILIDKKDEEVWDAIKKKLEYKNI
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease AddB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 1 subfamily.
Protein: SYR_YERPN
Sequence: MNIQALLSDKVSQALIAAGAPADCEAQVRQSAKAQFGDYQANGVMAVAKKLGMQPRQLAERVVELLDLTGIASKIEIAGPGFINIFLDRQWVAEKVEYALTAPKLGVAPVEPQTIVVDYSAPNVAKQMHVGHLRSTIIGDAAVRTLAFLGHNVIRANHVGDWGTQFGMLIAYLEKMQNENASDMGLSDLELFYQQAKKTYDEDEEFSLRARAYVVKLQSGDEYCRQMWRKLVDITMAQNQVAYDRLNVTLTKDDVMGESLYNAMLPEIVADLKAKGLAVESEGATVVYLDEYKNKDGEPMGVIIQKKDGGYLYTTTDIACAKYRYETLGADRILYYIDSRQHQHLMQAWTIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRSGGTVKLSDLLDEAVERAGKLIAEKNPDMPADELKQVINAVGIGAVKYADLSKSRTTDYIFDWDNMLALDGNTAPYMQYAYTRVVSVFRRAGVDETSLTLPLVVTEDREATLATRLLQFEEIITTVAREGTPHVMCSYLYDLAGLFSSFYEHCQILNAESEEIRQSRLKLAMLTAKTLKQGLDTLGIQTVERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU6C_ZYGCR
Sequence: MIPISESTNTLLFVVLEFAILVGALGVVLLSRVIYSALLLGFVFICVALLYLLLNADFLAAAQVLIYVGAVNVLIVFAIMLVSTPDDVKNKPKTTGEIISAFTFIALFVLLTIMIFTTSWDTHHNLATQDEVLLQPLMSNVQTIGFHLLTDLLFPFELLSLLLLVALVGAITIASKNKITE
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 6, chloroplastic, NAD(P)H dehydrogenase subunit 6, NADH-plastoquinone oxidoreductase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: TAL_PHOPR
Sequence: MSTKLEQLRALTTVVADTGDIEAISKYQPEDATTNPSLILKAAQIAEYAPLIDASIAYAKAQSNDKTQQVADTCDMLAVNIGKEILKVVPGRISTEVDARLSYDTEGSVIKARQLIKMYNDAGITNDRILIKLASTWEGIRAAEVLEKEGINCNLTLLFSFAQARACAEAGVFLISPFVGRIMDWYKAKEGRDFESSEDPGVVSVTGIYDYYKTYGYNTVVMGASFRNIGEILELAGCDRLTISPNLLQELEDATGEVVEKLIDTNGTKERPAAMTHAEFLWEHNQDPMAVEKLADGIRNFAVDQGKLEVMIAERL
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBB_PHOVI
Sequence: VHLTGEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFDSFGDLSSADAIMGNPKVKAHGKKVLNSFSDGLKNLDNLKGTFAKLSELHCDKLHVDPENFKLLGNVLVCVLAHHFGKEFTPQVQAAYQKVVAGVANALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: PUSL1_HUMAN
Sequence: MSSAPASGSVRARYLVYFQYVGTDFNGVAAVRGTQRAVGVQNYLEEAAERLNSVEPVRFTISSRTDAGVHALSNAAHLDVQRRSGRPPFPPEVLAEALNTHLRHPAIRVLRAFRVPSDFHARHAATSRTYLYRLATGCHRRDELPVFERNLCWTLPADCLDMVAMQEAAQHLLGTHDFSAFQSAGSPVPSPVRTLRRVSVSPGQASPLVTPEESRKLRFWNLEFESQSFLYRQVRRMTAVLVAVGLGALAPAQVKTILESQDPLGKHQTRVAPAHGLFLKSVLYGNLGAASCTLQGPQFGSHG
What are the official names of this protein?
tRNA pseudouridine synthase-like 1, tRNA pseudouridylate synthase-like 1, tRNA-uridine isomerase-like 1.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: SOFL1_ARATH
Sequence: MESPRNHGGSEEEEYSSCESGWTMYIEDAFHGNDQSSVVVDDDDDDTQVKEADDGYENDDGDTSDDGGDEESDDSMASDASSGPSNQLPKHINKHAARKNGSKQVYLQKRQHTEKTISNEGEKSDLKARTRTSAASRVQSRGKVSKTK
What is the function of this protein?
Involved in cytokinin-mediated development (PubMed:20011053, PubMed:29467189).  Together with SOFL2, triggers the endogenous content of specific bioactive cytokinins derived from the biosynthetic intermediates trans-zeatin riboside monophosphate (tZRMP) and N(6)-(Delta(2)-isopentenyl)adenosine monophosphate (iPRMP) such as N-glucosides trans-zeatin 7-glucoside (tZ7G), cis-zeatin 7-glucoside (cZ7G) and N(6)-(Delta(2)-isopentenyl)adenine 7-glucoside (iP7G) (PubMed:20011053).
What are the official names of this protein?
Protein SOB FIVE-LIKE 1, AtSOFL1.
What is the protein family that this protein belongs to?
Belongs to the SOFL plant protein family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: FIBB_ANTAM
Sequence: QPSYDYDEEEDDRAKLRLDAR
What is the function of this protein?
Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix.  Fibrin has a major function in hemostasis as one of the primary components of blood clots.  In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization.  Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood.  However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo.  Enhances expression of SELP in activated platelets.  Maternal fibrinogen is essential for successful pregnancy.  Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage.  May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.
What are the official names of this protein?
Fibrinogen beta chain.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS6_SHEB5
Sequence: MLAKRLVPCLDVKDGKVVKGVQFRNHEIVGDIVPLAARYAEEGADELVFYDITASAHERVVDKSWVSRVAEQIDIPFCVAGGIKTISQARELLAFGADKISINSPALTDPSLISRLQDEFGRQCIVIGIDSFFDATSNSYKVKQFTGDEAATKDTQWFTQDWVEEVQKRGCGEIVLNVMNQDGVRGGYDIKQLSLVRAICDVPLIASGGAGTMAHFRDVFIEAKVDAALAASVFHKAIINIGELKAYLAAEDIAIRR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK20_WELMI
Sequence: MTRVKRGYIARRRRNRIRLFASGFKGSHSKQFRAAKQQKQRALISAKGDRIKRKRAFRRLWIARINAAVRFYGVSYSKFVHCMYKNQLPLNRKTLAQMATLHNPCFSTISQKIVA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: STK19_MOUSE
Sequence: MNRKRRLLASEAFGVKRRRAPGPVRADPLRTRAGSAREAIEELVKLFPRGLFEDALPPIALRSQVYSLVPDRTVADLQLKELQELGEIRIIQLGFDLDAHGIVFTEDYRTRVLKACDGRPCAGAVQKFLASVLPACGDLSFQQDQMTQTYGFRDPEITQLVNAGVLTVRDAGSWWLAVPGAGRFIKCFVKGRQAVLSMVRKAKYRELALSELLGRRAPLAVRLGLAYHVHDLIGAQLVDCVPTTSGTLLRLPDT
What is the function of this protein?
Serine/threonine-protein kinase that acts as a key regulator of NRAS signaling by mediating phosphorylation of NRAS at 'Ser-89', thereby enhancing NRAS-binding to its downstream effectors.
What are the official names of this protein?
Serine/threonine-protein kinase 19, Protein RP1.
What is the protein family that this protein belongs to?
Belongs to the STK19 family.
What are the subcellular locations of this protein?
Nucleus.