PharMolix/UniProtQA huggingface dataset:
Protein: PYRH_LACLM
Sequence: MAEIKYKRVLLKLSGEALSGEKGFGFDPETAKAVAEELKEVHDLGAELAIVCGGGNVWRGVTGEKAGMERAQADYMGMLATIQNGLFIQSALENIGVDTRVMTAIEMKAVAEPYIRRRAERHLEKGRVVIFAGGTGSPYFSTDTTSALRAAEINADVILMAKNGVDGVYNADPKLVADAIKFEHLTHMDVITKGLQVMDSTASTMSMDNHIPLVVFNMNEAGNITRVVRGEEIGTTVE
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYDND_CAMJE
Sequence: MRSHYNTDLGISHVGQSVKLCGWVNSYRDHGGVIFIDLRDRSGIIQLVCDPNDSKEAHEIASNARNEFVLITEGTIRPRGEGLVNPKLKTGEIEVVVSKLTIENESAVPPFAIADESVNEELRLKYRFLDLRNPKLYENFALRSKACIAARNSLANMGFLEVETPILTKATPEGARDYLVPSRVHQGEFYALPQSPQLFKQLLMCSGFDRYFQIAKCFRDEDLRADRQPEFTQIDVEMSFCEQKDVIKVAETFLKDIFKACGKEIQTPFRQMQYKDAMENYGSDKPDLRFDLKFIDVIDIFTKSNNEIFANIAKDTKKNRIKAIRVPKGDTIFSKRQMQRFEEFVRKFGAQGLAFIQVKKDGLKGPLCKFFSEEDLNELSKRCELEVGDVVFFGAGAKKTVLDYMGRFRIFLANELKLIDPNALEFLWVVDFPMFEQNDDGSYSAMHHPFTMPKNIDETDLEEISSIAYDVVLNGVELGGGSIRIHKNDIQQKVFKLLNIDEEQQKEKFGFLLDALSFGAPPHGGIAIGLDRLIMLVTGANSIREVIAFPKTQRAQCLMTDAPSPASNEAMRELGIKLRENIK
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 4HYPE_STRRD
Sequence: MRTKRVFHAVDSHTEGMPTRVITGGVGVIPGSTMAERREHFLAEMDHVRTLLMYEPRGHSAMSGAILQPPTRPDADYGVLYIEVSGCLPMCGHGTIGVATVLVETGMVEVVEPVTTIRLDTPAGLVVAEVRVEDGAATAVTITNVPSFSAGLDRTVKVPGIGEVTYDLAYGGNFYAILPIESVGLPFDRAHKQQILDAGLAIMDAINEQDEPVHPLDAGIRGCHHVQFTAPGSDARHSRHAMAIHPGWFDRSPCGTGTSARMAQLHARGELPLDTDFVNESFIGTRFVGRLVEETEVTDLPAVVPTITGRAWVTGTAQYFLDPRDPFPEGFLL
What is the function of this protein?
Catalyzes the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp).  Is likely involved in a degradation pathway that converts t4LHyp to alpha-ketoglutarate.  Displays no proline racemase activity.
What are the official names of this protein?
4-hydroxyproline 2-epimerase, 4Hyp 2-epimerase, 4HypE.
What is the protein family that this protein belongs to?
Belongs to the proline racemase family.
Protein: Y596_THESQ
Sequence: MFLPTTREEMKKLGWRELDVILVTGDAYVDHPSFGVALIGHYLVSHGFKVGIIAQPDWRTEKDITRLGRPRLFFGVTAGNVDSMVANYTASKKKRKTDDYTPGGSGGKRPDRATIVYTNLIKRFFPEVPVVLGGLEASLRRFAHYDWWSEKVRKSILIDSKVDLLVYGMGEKAVLEIAQILSRTGDIEKCKSVRGVVWWSSQKPEGGIELPSYDEISENPEKYAEALKLQTWYTDPYKNILIYQKQDTRYVVQNPPQLPLSQEELDRLYLLPFEREVHPFYAKMGRVKAIETVKFSITAVRGCFGSCSFCALTQHQTTHVSYRSKDSILEEVRILTKKKDFKGTITDVGGPTANLYGSSCSIRETKGQCQKFCLYPSVCKIVRPNHDEFISLLESIRKIPGVRNVFVSSGIRHDFVLAEKDPDVFIRELVKYTPGQLKLAPEHAHPKVLSLMRKPPVELFLEFKRRFETLAKKIGKRKYVIGYFIVGHPGEGWRENNYLRDFILKHLGYFPQQIQIFTPTPGTVSTAMYYSGLDPFTGEKVHVERSLKVRNKMKENVLFKKKGREKR
What are the official names of this protein?
UPF0313 protein TRQ2_0596.
What is the protein family that this protein belongs to?
Belongs to the UPF0313 family.
Protein: CYSQ_MYCBO
Sequence: MVSPAAPDLTDDLTDAELAADLAADAGKLLLQVRAEIGFDQPWTLGEAGDRQANSLLLRRLQAERPGDAVLSEEAHDDLARLKSDRVWIIDPLDGTREFSTPGRDDWAVHIALWRRSSNGQPEITDAAVALPARGNVVYRTDTVTSGAAPAGVPGTLRIAVSATRPPAVLHRIRQTLAIQPVSIGSAGAKAMAVIDGYVDAYLHAGGQWEWDSAAPAGVMLAAGMHASRLDGSPLRYNQLDPYLPDLLMCRAEVAPILLGAIADAWR
What is the function of this protein?
Phosphatase with a broad specificity.  Its primary physiological function is to dephosphorylate 3'-phosphoadenosine 5'-phosphate (PAP) and 3'-phosphoadenosine 5'-phosphosulfate (PAPS).  Thus, plays a role in mycobacterial sulfur metabolism, since it can serve as a key regulator of the sulfate assimilation pathway by controlling the pools of PAP and PAPS in the cell.  To a lesser extent, is also able to hydrolyze inositol 1-phosphate (I-1-P), fructose 1,6-bisphosphate (FBP) (to fructose 6-phosphate (F-6-P)) and AMP in vitro, but this might not be significant in vivo (By similarity).
What are the official names of this protein?
3'-phosphoadenosine 5'-phosphate phosphatase, PAP phosphatase, 3'(2'),5'-bisphosphate nucleotidase, 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase, D-fructose-1,6-bisphosphate 1-phosphohydrolase, DPNPase, Fructose-1,6-bisphosphatase, FBPase, Inositol-1-monophosphatase, I-1-Pase, IMPase, Inositol-1-phosphatase.
What is the protein family that this protein belongs to?
Belongs to the inositol monophosphatase superfamily.
Protein: YACG_RALSO
Sequence: MNMKTVKCPTCGKPVPWTPESRYRPFCSERCKQIDLGAWAAEQYTIPVVEDDDLPPDAPGGESGGASGRLN
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: KAD_DESOH
Sequence: MNILFFGPNGSGKGTQGAILKEKYSLPHIESGAIFRENISKGTELGAKAKEYIDRGDLVPDDITIPMILDRLQQDDCKKGWLLDGFPRNKVQAETLDATLKKANMALDIVVEIELDREIAKNRIMGRRLCVNDNNHPNNIFIDAIKPDGDKCRVCGGELKTRSDDQDEAAIDKRHNIYYDTETGTLAAAYYFRDLAAKGGSLKYITLDGAPGVKEVAAELVSKL
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGB_HELPJ
Sequence: MHSDELLVEVLVEELPAQALLNEYKEMPKKLHALFQKRALEVGNIEVFYTPRRLCLFVKDFPLLTQETKEEFFGPPVKIACNNQDKTQGLNALGLGFYQKLGLKDHQHFQTAFKSNKEVLYHAKIHAKQPTKDLIMPIVLEFLEGLNFGKSMRWGNVEKSFIRPIHNICVLFNGENFNDIEIKEYGFKTKQATKAHRQEGFDFIEVDSPKAYFEVLEKNHVILDPKKREAKILQEIKGLEKKHDIIVEVDRDLLDEVVAITEYPTALLGEFDKAFLKLPSEIITTSMKENQRYFAIFNQKSQEESPTLHNGFIVVSNAISKDKQKIILGNQKVLKARLSDAVFFYENDLKKPLDNAPLESVVFVQGLGTLKDKMERESIIAQYLTQKYISSLSMPLEKALELISRAIQIAKADLLSEVVYEFSELQGIMGYYYALKQNENELVALSVKEQYLPASENAPLPSSVFSSIVALSLKIDSLFSLFSVGKIPSGSKDPFALRRLSFGLLKIIAHYGLEFDLKADLKNLFEKVGVYQSFDLEVLEKFLLERFHNLIDCNLSIIRSVLNTNERDIVKIIQKVKALKRFLDNPKNAQKKELLFSAFKRLANINKDRNPNESSGFSTSLFKELQEHALFEAFNAIKTSTFESLDSKIEAYFGLHAPLEEYFKSVLVMDKDIEIQKNRKNFLWGVYQSFLEIGDIKEIAI
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSH_ENT38
Sequence: MSLLDLNALNDLPKVERILALAETNAKLEKLDAEGRVAWALENLPGEYALSSSFGIQAAVSLHLVNTIRPDIPVILTDTGYLFPETYQFIDELADKLKLNLKVYRAEQSAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALEELNVKTWFAGLRREQSGSRASLPVLGIQRGVFKVLPIIDWDNRTVYQYLQKHGLKYHPLWDQGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
What is the function of this protein?
Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
What are the official names of this protein?
Phosphoadenosine 5'-phosphosulfate reductase, PAPS reductase, 3'-phosphoadenylylsulfate reductase, PAPS reductase, thioredoxin dependent, PAPS sulfotransferase, PAdoPS reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_KOSOT
Sequence: MGLKKFKPVTPGRRFMLIPDYSEITKTEPEKSLLVPLKKKAGRNHHGHVTVRHQGGGHKRMYRIIDFKRNKFGIPARVASIEYDPNRTARIALLVYADGEKRYILAPKGLKVGDTIMNGPDAEITVGNALPLANIPVGTIVHNIEFIPGKGGQIARSAGTYAQLMAKEGRYALLRMPSGELRKVLVTCMATIGMVGNEDHSNEVHGKAGRKRWLGIRPTVRGMTMNPVDHPMGGGEGRSKGHIPQSPWGIPAKGYKTRKSKKPSDKLIVKRRKQK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: SYK_THEVB
Sequence: MADVGATGAEIRATRIEKAKTLQAQGMSPYAYRWERTHTAALLQDKYAHLAAGEAVGDRVSVAGRIMARRIFGKLAFFTLQDDSGTIQLYLDKQTISQTMGEAAFADLKHLTDVGDILGAVGTLKRTEKGELSVVVESYTMLTKSLLPLPDKWHGLTDVEKRYRQRYVDLIVNPQVRDTFRKRALITAAIRRYLNEQGFIEIETPVLQVEAGGAEARPFITYHNTLEMQLYLRIATELHLKRLIVGGFEKVYELGRIFRNEGISTKHNPEFTSIEVYQAYADYNDMMTLTEAIITTGAMEVLGTLKITYQGETIDLTPPWRRVTMHDAVLAATGIDFRQLGDLTAAKIAAQKVGVKDLDTCDTIGRVLNEVFEQIVEPTLIQPTFVLDYPVEISPLAKPHRSQPGLVERFELFIVGREHANSFSELTDPLDQRQRLEEQARRKAAGDLAAHSVDEDFLTALEHGMPPTGGLGIGIDRLVMLLTDSPSIRDVIAFPLLRPESAGGQV
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQO9_SCHPO
Sequence: MSDFPPSYQQHENDRMVPQESSTSNNASEFNVPKKSNRRLSVVQQDESVLNREFDDLTPEVGFDADKWERKTKHPNPQKPFDFKRKPEKKYHSKSDVGF
What are the official names of this protein?
Uncharacterized protein C569.09.
Protein: MTNA_PARD8
Sequence: MRFNEQADGVIILDQTLLPGKEAYLTLTTAEEIWDAIYKLKVRGAPAIGVAAAYGIYVCARRIDTAEKSVFVNEFRKIKEYLAGSRPTAVNLVAALNRMERVLVAHPTLSVPEWKELLYKEAIAIREEDAAACRQIGENCLELLRPGMGILTHCNAGHLAVSEYGTALAPIYLGQERGYGFKVFADETRPLLQGARLTAYELSRAGVDVTLICDNMASVVMRKGWVHAVVVGCDRVAANGDVANKIGTSGVAILARHYKIPFYVLGPTSTIDGSCPDGDSIVIEERNPDEVTEMWYSRRMAPKDVKVYNPAFDITPHELITAIITEKGIFYKNNR
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: MYPR_TAEGU
Sequence: MGLLECCARCLIGAPFASLVATGLCFFGVALFCGCGHEALTGTEQLIETYFSKNYQDYEFLIDVIHGFQYFIYGTAAFFFLYGALLLAEGFYTTGAVRQIFGDYRTTICGKGLSATVTGGPKGRGARGPQRAHSWQRVCHCLGKWLGHPDKFVGITYVLTIIWLLVFACSAVPVYIYFNTWTTCQSIGNPTKTSASIGTLCADARMYGILPWNAFPGKVCGSNLLSICKTSEFQMTFHLFIAAFVGAAATLVSLVTFIIATTYNFAVLRLMGRGTKF
What is the function of this protein?
This is the major myelin protein from the central nervous system.  It plays an important role in the formation or maintenance of the multilamellar structure of myelin.
What are the official names of this protein?
Myelin proteolipid protein, PLP, Lipophilin.
What is the protein family that this protein belongs to?
Belongs to the myelin proteolipid protein family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NMDZ1_RAT
Sequence: MSTMHLLTFALLFSCSFARAACDPKIVNIGAVLSTRKHEQMFREAVNQANKRHGSWKIQLNATSVTHKPNAIQMALSVCEDLISSQVYAILVSHPPTPNDHFTPTPVSYTAGFYRIPVLGLTTRMSIYSDKSIHLSFLRTVPPYSHQSSVWFEMMRVYNWNHIILLVSDDHEGRAAQKRLETLLEERESKAEKVLQFDPGTKNVTALLMEARELEARVIILSASEDDAATVYRAAAMLNMTGSGYVWLVGEREISGNALRYAPDGIIGLQLINGKNESAHISDAVGVVAQAVHELLEKENITDPPRGCVGNTNIWKTGPLFKRVLMSSKYADGVTGRVEFNEDGDRKFANYSIMNLQNRKLVQVGIYNGTHVIPNDRKIIWPGGETEKPRGYQMSTRLKIVTIHQEPFVYVKPTMSDGTCKEEFTVNGDPVKKVICTGPNDTSPGSPRHTVPQCCYGFCIDLLIKLARTMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLDRFSPFGRFKVNSEEEEEDALTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLSILKSHENGFMEDLDKTWVRYQECDSRSNAPATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKRHKDARRKQMQLAFAAVNVWRKNLQDRKSGRAEPDPKKKATFRAITSTLASSFKRRRSSKDTSTGGGRGALQNQKDTVLPRRAIEREEGQLQLCSRHRES
What is the function of this protein?
Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium.  Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+) (PubMed:1350383, PubMed:1834949, PubMed:1388270, PubMed:8428958, PubMed:18177891, PubMed:28384476, PubMed:15996549, PubMed:24876489, PubMed:27135925, PubMed:27618671, PubMed:28468946).  Sensitivity to glutamate and channel kinetics depend on the subunit composition (PubMed:28384476).
What are the official names of this protein?
Glutamate receptor ionotropic, NMDA 1, GluN1, Glutamate [NMDA] receptor subunit zeta-1, N-methyl-D-aspartate receptor subunit NR1, NMD-R1.
What is the protein family that this protein belongs to?
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR1/GRIN1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane. Postsynaptic density. Note=Enriched in postsynaptic plasma membrane and postsynaptic densities.
Protein: RPE_ENCCU
Sequence: MHLGMLKKRIGISILDCNFGNLEEELGELKRNGVTNIHLDVMDTTFVKNITFGPCIINRILEHDFVFDVHMMVESPLDIIMQIDLERVSLVTIHSEVCDKAGVAEYLRKRNVLFGIALNPETQVDDAEMRSADFVLIMSVKPGFGGQKFQEECLAKVEEVRRYGKMVGIDGGIEMSNIGRITGADYAVVGSGYFRSGDRKKFLRDITDEFLCGSCSG
What is the function of this protein?
Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
What are the official names of this protein?
Ribulose-phosphate 3-epimerase, Pentose-5-phosphate 3-epimerase, PPE, RPE.
What is the protein family that this protein belongs to?
Belongs to the ribulose-phosphate 3-epimerase family.
Protein: NIP32_ORYSJ
Sequence: MEGGKMSSMGMDAASASVTVPPMQMQAGDQSNRIAIIISPRAGSSKILPFELVNGAANAGSQRHADPAESTPEAHHHLWHPVDLPKIKPPVPLVKKVGAEFFGTFTLIFTVLSTIIMDEQHKGVESLLGIATSAGLAVTVLVLSLIHISGCHLNPAVSIAMTVFGHLPPAHLLPYIAAQILGSITASFAVKGMYHPVNPGIVTVPKVGTVEAFFLEFVTTFVLLFIITALATDPNAVKELIAVAVGATIMMNALVAGPSTGASMNPARTLGPAIATGRYTQIWVYLVATPLGAVAGEGFYFAIKL
What is the function of this protein?
Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
What are the official names of this protein?
Aquaporin NIP3-2, NOD26-like intrinsic protein 3-2, OsNIP3;2.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family. NIP (TC 1.A.8.12) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: OTC_CAMJJ
Sequence: MKHFLTLRDFSKEEILSLVNHASELKKEPKKLLQDKTLAMIFEKNSTRTRMAFELAITELGGKALFLSSNDLQLSRGEPVKDTARVIGAMVDFVMMRVNKHETLLEFARYSKAPVINALSELYHPTQVLGDLLTIKEWNKMQNGIAKVAFIGDSNNMCNSWLIAAAILGFEFSIAIPKNYKISPEIWEFAMKQALISGAKISLSHDKFEALKDKDVVITDTWVSMGEENEKERKIKEFEGFMIDEKAMSVANKDAILLHCLPAYRGYEVSEEIFEKHADVIFEEARNRLYVVKALLCFLDNQRGRE
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCUP_SHESH
Sequence: MAELKNDRYLRALLKQPVDRTPVWMMRQAGRYLPEYKATRAEAGDFMSLCKNQDLACEVTLQPLRRYDLDAAILFSDILTVPDAMGLGLYFETGEGPRFQRPTDTIDSIKKLCIPDPEDELGYVMRAVSTIRRELKGEVPLIGFSGSPWTLATYMVEGGSSKTFEKIKKMAYEEPATLHLLLDKLADSVILYLNAQVANGAQSLMIFDSWGGALSHHAYREFSLRYMQKIVDGLTRHADGRQVPVTLFTKGGGLWLESMAETGCDALGLDWTVDIGDARRRVGHKVALQGNMDPSVLYASPERIHQEVDQILSSYGEGTGHVFNLGHGIHQHVDPEHAGSFINSVHELSAQYHK
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10E_PYRCJ
Sequence: MPARPARCYRRIKGPPYTREEYIHGAPMIQIPKFDMGTTSAAARAAFTMVAKLVAEERGQIRMQALEAARQISSKYLTKYVGDANYYLRLNVVPHHVLRENRMLAMAGADRLQEGMRLAFGSPAGRAARVEPGQVIFYVEFKPEHLAHVKEALRRAASKLPIPTRIVVEPKGDGKTAS
What are the official names of this protein?
50S ribosomal protein L10e.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: QUEF_XYLFA
Sequence: MNTSHYSVLGHAVPYPKAYDPSLLFPISRAVGRAQIGIGVVLPFVGEDRWHAYELSWLDARGKPCVATATFHVPCDSPYLIESKSLKLYLNSFSAEVFNRAEALRLRIAADLSACAGAAVAVEFGLPPVGGGDKEISLDRLNVDIEDYGPPNPDYLSNVAQNLIEEMVEETLTSTLFKSNCPVTGQPDWASVTVRYFGVPIDHEGLLRYFISFRHHAEFHEQCVERIFQDVLQRCSPQCLAVEARYTRRGGLDINPLRTTSEMAWPISVFRDPRQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTPPA_THET8
Sequence: MGSGKPPLILASGSPRRKALLEALGYPIRVAVPGVEEEGLPLPPKALAQALARRKGEAVQGEWVLAADTVVDLDGEVLGKPKDPEENRLFLRRLSGRLHLVHTAFYLRTPKEVVEEVHTARVFFRPLSEEEIAWYVGSGEGLDKAGGYGAQGLGMALLERVEGDFYTVVGLPVSRVFALLWARGFRP
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCNK9_XENLA
Sequence: MKRQNVRTLSLIICTFTYLLVGAAVFDALESDYEMREEEKLKAEEIRLKGKYNISSEDYRQLELVIMQSEPHRAGVQWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPLTLVMFQSLGERMNTFVKYLLKRIKKCCGMHSTDVSMENMVTVGFFSCMGTLCIGAAAFSHYEEWSFFQAYYYCFITLTTIGFGDYVALQKNRALQKKPLYVAFSFMYILVGLTVIGAFLNLVVLRFLTMNSEDERRDAEERASLAGNRNSMIIHIQEDTPHGRQRYKAEVTDLQSVCSCMCYRSHEYTSRMVSHQNSFSSKLNPQYFHSISYKIEEISPSTLKNSLFPSPVSSVSPGLHSFTDKHRLMKRRKSI
What is the function of this protein?
pH-dependent, voltage-insensitive, background potassium channel protein.
What are the official names of this protein?
Potassium channel subfamily K member 9.
What is the protein family that this protein belongs to?
Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: XGPT2_HAEI8
Sequence: MSEKYVVTWDMFQMHARKLSERLLPASQWKGIIAVSRGGLFPAAVLARELGLRHIETVCIASYHDHNNQGELQVLHAAQVPNGGEGFIVVDDLVDTGNTARAIRQMYPNAKFVTVFAKPAGAELVDDYVIDIPQNTWIEQPWDLGLTFVPPLSRK
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi.  To a lesser extent, also acts on hypoxanthine.
What are the official names of this protein?
Xanthine-guanine phosphoribosyltransferase 2, XGPRT 2, Xanthine phosphoribosyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DPY5_CAEEL
Sequence: MVKAVVGFGAACGISAIVACLWAALVITNDINDMYDDVMGELGGFRDISDDTWGTLLDVRHGAGESAEQYVRGIFGRHKRSNSQCSCGLPSQGCPAGAPGNPGAPGEPGGTGPDGKNGPTGLPGLNIPIPNDFPKECIKCPAGPPGQDGLPGQEGFQGLPGDAGKRGTPGKDGEPGRVGDIGDQGTPGQDGQPGLAGPPGRDGLTGKGQPGVAGRPGMPGPRGEPGNNGNPGEEGQTGAQGPTGQPGKDGFNGNDGTPGQAGPQGAVGADAEYCPCPERKRRRV
What is the function of this protein?
Nematode cuticles are composed largely of collagen-like proteins.  The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment.
What are the official names of this protein?
Cuticle collagen dpy-5, Protein dumpy-5.
What is the protein family that this protein belongs to?
Belongs to the cuticular collagen family.
Protein: ACCD_STACT
Sequence: MFKDFFNRGSKKKKYVTVQDSKQNDVPTGIMTKCPKCKKIMYTKELSENLNVCFNCDHHLSLTAYKRIEAISDEGTFKEFDKGMTSANPLDFPGYEEKIKKDQEKTGLDEAVVTGTAELGGIEYGVAVMDARFRMGSMGSVVGEKICRIIDYCTEHRLPFILFSASGGARMQEGIISLMQMGKTSVSLKRHSDAGLLYISYITNPTTGGVSASFASVGDINLSEPKALIGFAGRRVIEQTINEKLPDDFQTAEFLLEHGQLDKVVHRKEMRSTLESILKMHAGQEVNKDA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_BIFA0
Sequence: MAKHSKKYREAAERIDRNNLYTPEEAIALLKSMPAYNFDQTVEAVLRLNVDPRKADQLVRGSVNLPNGTGKTAKVLVFARGPKATEALEAGADIVGDDDLVEKVANGFLDFDSVVATPDMMGKVGRLGRVLGPRGLMPNPKTGTVTMDVTKAIKDIKGGKVDFRVDKNGNLSFLFGKLSFSAEALDQNFRAVADEVKRLKPATVKGRYITKATISSTMNPGIPVDPASI
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: BAMA_CITK8
Sequence: MAMKKLLIASLLFSSATVYGAEGFVVKDIHFEGLQRVAVGAALLSMPVRTGDTVNDEDISNTIRALFATGNFEDVRVLRDGDTLLVQVKERPTIASITFSGNKSVKDDMLKQNLEASGVRVGESLDRTTLSDIEKGLEDFYYSVGKYSASVKAVVTPLPRNRVDLKLVFQEGVSAKIQQINIVGNHAFSTDELISHFQLRDEVPWWNVVGDRKYQKQKLAGDLETLRSYYLDRGYARFNIDSTQVSLTPDKKGIYITVNITEGDQYKLSGVQVSGNLAGHSAEIENLTKIEPGELYNGTKVTKMEDDIKKLLGRYGYAYPRVQSQPEINDADKTVKLRVNVDAGNRFYVRKIRFEGNDTSKDSVLRREMRQMEGAWLGSDLVDQGKERLNRLGYFETVDTDTQRVPGSPDQVDVVYKVKERNTGSFNFGIGYGTESGVSFQAGVQQDNWLGTGYSVGINGTKNDYQTYTELSVTNPYFTVDGVSLGGRIFYNDFQADDADLSDYTNKSYGTDVTLGFPINEYNTLRAGLGYVHNSLSNMQPQVAMWRYLNSMGEYPSNTNDRNSFSANDFTFNYGWTYNKLDRGFFPTEGTRVNLNGKVTIPGSDNEYYKATLDTATYVPIDDDHKWVVLGRTRWGYGDGIGGKEMPFYENFYAGGSSTVRGFQSNTIGPKAVYYPASSRHDGDDDYDNDCKSTETAPCKSDDAVGGNAMAVASLEFITPTPFISDKYANSVRTSFFWDVGTVWDTNWDSNAYAGYPDYSDPSNIRMSAGIALQWMSPLGPLVFSYAQPFKKYDGDKSEQFQFNIGKTW
What is the function of this protein?
Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.  Constitutes, with BamD, the core component of the assembly machinery.
What are the official names of this protein?
Outer membrane protein assembly factor BamA.
What is the protein family that this protein belongs to?
Belongs to the BamA family.
What are the subcellular locations of this protein?
Cell outer membrane.