PharMolix/UniProtQA huggingface dataset:
Protein: EFTS_SHEB2
Sequence: MAITAAQVKELRDRTGAGMMDCKNALTETNGDMELAIDNMRKSGAAKAAKKAGNIAADGTILIKNGEGFAALLEVNCQTDFVAKDSNFLAFANAVLDAAAASKVTLEDLKAQFEDARVALVTKIGENINIRRVEYIDGANLSSYRHGERIGVVVAGEADEETLKHIAMHVAASKPEYVNPEDVPAEIVAREQALQIEMSMNEGKSAEIAEKMVLGRMKKFTGEISLTGQAYIMEPKKTVGEILKEKGAKVTNFIRLEVGEGIEKKEEDFAAEVAAQIAASKKA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SGS3_DROYA
Sequence: MKLTIAISLASILLLSVAHVAQGCDCGCPTTSPKPCQTTVPTCAPTTTTTTTTTCAPPTRPPPPPCTDAPTTTKRTTEKSTTRRTTTTTRQTTTRPTTTTTTTTTTRRPTTRSTTTRHTTTTTTTTRRPTTTTTTTRRPTTTTTTTRRPTTTTTTTRRPTTTTTTTRLPTTRSTTTRQTTKSTTSKRPTHETTTTSKRPTQETTTTTRRATQATTTPKPTNKPGCGCKSCGPGGIPCGSCPKRQGLCTELNNLLRQLERRVRECVCGQPVWLL
What are the official names of this protein?
Salivary glue protein Sgs-3.
Protein: ARCSA_THEAC
Sequence: MIEDQALFGYARYGKVDDVVYPSVIASGNGINYGDSDIEILGDRIPRQILYPAKIKQEILETDKLVIIPNGAELVRKPKDLVRIIMDIHSRYGFSKLIMISGISDPYSIPALVYLGISFFDSSILEMEGKMGYRFTPFGIEKADHDVSSENAIFISDMMHIIQRSISDGTLRELIEKAVISSKAAEMVRIADYSYYQDFESVFPVRTPYIKANTIEDLYRPDLIRYRNYISESYVKPDADIALILPCSAKKPYSRSKSHQKVIGALGNLRRFIHEVIVTSPIGIVPRDLEETYPARFYDIPVIGLWYEDEKIMMKRMMSSYMGRNRYRKVIAFIPEDLDFITEAIPYPHEVIEFKSSNLQRLREVIQREIAGGKAVNQKVAKYNSILRYQFGEWILPLVSGYTIRRNYNQDMIVKDGKILFVYNENLGKFTINKASADMFIKNGKFLVEIDDFKPTSNVYAMGVVDATEDIRQEDEVVLVHSGEVRGVGIAKMPARAMIELKKGIAVKVR
What is the function of this protein?
Functions in the biosynthesis of archaeosine, a modified nucleoside present in the dihydrouridine loop (D-loop) of archaeal tRNAs.  Catalyzes the addition of L-lysine to the cyano group of 7-cyano-7-deazaguanine (preQ0)-modified tRNAs at position 15, to generate q0kN15-tRNA, a q0N lysine adduct identified as 7-N-[(5S)-5-amino-5-carboxypentyl]formamidino-7-deazaguanosine.
What are the official names of this protein?
Archaeosine synthase subunit alpha, Archaeosine synthase, lysine transferase subunit.
What is the protein family that this protein belongs to?
Belongs to the archaeosine synthase type 1 family.
Protein: ODPB_CHATD
Sequence: MSRFLRPAFRLATTATRASTIRPTPSSLITKAAAVPTTRLLQKRSYAAEATGVKEYTVREALNEALAEELESNPKVFILGEEVAQYNGAYKVTKGLLDRFGEKRVIDTPITEMGFAGLAVGAALAGLQPVCEFMTFNFAMQAIDHIVNSAAKTLYMSGGIQPCNITFRGPNGFAAGVAAQHSQDYAAWYGSIPGLKVVSPWSAEDAKGLLKAAIRDPNPVVVLENELMYGVSFPMSEAAQKDDFVLPFGKAKIERAGKDLTIVSLSRCVGQSLVAAENLKKKYGIEAEVINLRSIKPLDVEAIVKSVKKTHRLLAVESGFPAFGVGAEILALTMEYAFDYLDTPAQRITGADVPTPYAQKLEEMSFPTEQLIEDYAAKMLRV
What is the function of this protein?
The 10-megadalton pyruvate dehydrogenase complex contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) and catalyzes the overall oxidative decarboxylation of pyruvate to form acetyl-CoA and CO(2) (PubMed:33567276, PubMed:34836937).  Within the complex, pyruvate and thiamine pyrophosphate (TPP or vitamin B1) are bound by pyruvate dehydrogenase E1 subunits alpha and beta and pyruvate is decarboxylated leading to the 2-carbon hydrohyethyl bound to TPP.  The E2 component contains covalently-bound lipoyl cofactors and transfers the hydroxyethyl group from TPP to an oxidized form of covalently bound lipoamide, and the resulting acetyl group is then transferred to free coenzyme A to form acetyl-CoA and reduced dihydrolipoamide-E2.  Finally, the flavoprotein dihydrolipoamide dehydrogenase (E3) re-oxidizes the lipoyl group of dihydrolipoamide-E2 to form lipoamide-E2 and NADH.  A fourth subunit, E3BP, is responsible for tethering E3 in proximity to the core, forming the entire metabolon (Probable).
What are the official names of this protein?
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial, Pyruvate dehydrogenase complex component E1 beta, PDHE1-B.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ISPH_PSEFL
Sequence: MQIKLANPRGFCAGVDRAIEIVNRALEVFGPPIYVRHEVVHNKFVVEDLRARGAIFVEELDQVKDDVIVIFSAHGVSQAVRTEAAGRGLKVFDATCPLVTKVHIEVARYSRDGRECILIGHAGHPEVEGTMGQYDASNGGAIYLVEDEKDVANLQVHNPERLAFVTQTTLSMDDTSRVID
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: IF2_SALCH
Sequence: MTDVTLKALAAERQVSVDRLVQQFADAGIRKSADDSVSAQEKQTLLAHLNREAVSGPDKLTLQRKTRSTLNIPGTGGKSKSVQIEVRKKRTFVKRDPQEAERLAAEEQAQREAEEQARREAEEQAKREAQQKAEREAAEQAKREAAEKAKREAAEKDKVSNQQTDDMTKTAQAEKARRENEAAELKRKAEEEARRKLEEEARRVAEEARRMAEENKWTATPEPVEDTSDYHVTTSQHARQAEDENDREVEGGRGRGRNAKAARPAKKGKHAESKADREEARAAVRCGKGGKRKGSSLQQGFQKPAQAVNRDVVIGETITVGELANKMAVKGSQVIKAMMKLGAMATINQVIDQETAQLVAEEMGHKVILRRENELEEAVMSDRDTGAAAEPRAPVVTIMGHVDHGKTSLLDYIRSTKVASGEAGGITQHIGAYHVETDNGMITFLDTPGHAAFTSMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAAGVPVVVAVNKIDKPEADPDRVKNELSQYGILPEEWGGESQFVHVSAKAGTGIDELLDAILLQAEVLELKAVRKGMASGAVIESFLDKGRGPVATVLVREGTLHKGDIVLCGFEYGRVRAMRNELGQEVLEAGPSIPVEILGLSGVPAAGDEVTVVRDEKKAREVALYRQGKFREVKLARQQKSKLENMFANMTEGEVHEVNIVLKADVQGSVEAISDSLLKLSTDEVKVKIIGSGVGGITETDATLAAASNAILVGFNVRADASARKVIESESLDLRYYSVIYNLIDEVKAAMSGMLSPELKQQIIGLAEVRDVFKSPKFGAIAGCMVTEGTIKRHNPIRVLRDNVVIYEGELESLRRFKDDVNEVRNGMECGIGVKNYNDVRVGDMIEVFEIIEIQRTIA
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCD_STRSE
Sequence: MALFRKKDKYIRINPNRSRIESAPQAKPEVPDELFSKCPACKVILYKNDLGLEKTCQHCSYNFRITAQERRALTVDEGSFEELFTGIETTNPLDFPNYLEKLAATRQKTGLDEAVLTGKATIGGQPVALGIMDSHFIMASMGTVVGEKITRLFELAIEERLPVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTVLTDPTTGGVTASFAMEGDIILAEPQTLVGFAGRRVIESTVRENLPDDFQKAEFLQEHGFVDAIVKRQDLPATISRLLRMHGGVR
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: D106A_PANTR
Sequence: MRTFLFLFAVLFFLTPAKNAFFDEKCNKLKGTCKNNCGKNEELIALCQKSLKCCRTIQPCGSIID
What is the function of this protein?
Has antibacterial activity.  Acts as a ligand for C-C chemokine receptor CCR2.
What are the official names of this protein?
Beta-defensin 106A, Beta-defensin 6, BD-6, DEFB-6, cBD-6, Defensin, beta 106, Defensin, beta 106A.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted. Membrane. Note=Associates with tumor cell membrane-derived microvesicles.
Protein: PANE_STRP1
Sequence: MLVYIAGSGAMGCRFGYQISKTNNDVILLDNWEDHINAIKENGLVVTGDVEETVKLPIMKPTEATQEADLIILFTKAMQLPQMLQDIKGIIGKETKVLCLLNGLGHEDVIRQYIPEHNILMGVTVWTAGLEGPGRAHLQGVGALNLQSMDPSNQEAGHQVADLLNEANLNATYDENVVPNIWRKACVNGTMNSTCALLDCTIGELFASEDGLKMVKEIIHEFVIVGQAEGVELNEEEITQYVMDTSVKAAHHYPSMHQDLVQNHRLTEIDFINGAVNTKGEKLGINTPYCRMITELVHAKEAVLNIQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
What are the official names of this protein?
2-dehydropantoate 2-reductase, Ketopantoate reductase, KPR.
What is the protein family that this protein belongs to?
Belongs to the ketopantoate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPH_ECODH
Sequence: MNFLAHLHLAHLAESSLSGNLLADFVRGNPEESFPPDVVAGIHMHRRIDVLTDNLPEVREAREWFRSETRRVAPITLDVMWDHFLSRHWSQLSPDFPLQEFVCYAREQVMTILPDSPPRFINLNNYLWSEQWLVRYRDMDFIQNVLNGMASRRPRLDALRDSWYDLDAHYDALETRFWQFYPRMMAQASRKAL
What is the function of this protein?
Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP.
What are the official names of this protein?
Acyl carrier protein phosphodiesterase, ACP phosphodiesterase.
What is the protein family that this protein belongs to?
Belongs to the AcpH family.
Protein: MDM10_UNCRE
Sequence: MIDFIDYIQLSFSDATRWNRDNSYTALTDTANALLDFSIPERLRVHLSSLSTPQFATTYTLGTVGLIDGSISYLFSTLPLQTTQSRSTLIPLRKLVPGYRQIHPPLAPESWDSDGPGHEGSDGQEDETTPWKRRRETLLHAILHLPPPTTLNGLFLRRLSPTTQLSVAVCSTQAKPLSKSTPQASILTQLSHDTGKYSAEFLFSTDNALLGFKGLYNFGPDPRDRTNAQRPQRASQSVSLLSAGGEMYYSPLSSVVGLSTGLRFTTLPAASETLHSPSSSAYPAPSPISTFPYTLTLTLTPLTGSLSTTYSLLASPNLAFSSRFGFNVYSWESEMVAGCELWRQKRKPYPYVSGEKDDLAWAKRKMGLLPPLPAPPTPAKRMDLTAGAGESVESDSVIKLRVDQSLNIRLLWEGRVKDLLVSAGVGLGPTSLSTGGAAYGWTGVGVSVLYST
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange.  MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex).  Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins.  Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins.  May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway.  Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 10, Mitochondrial inheritance component MDM10.
What is the protein family that this protein belongs to?
Belongs to the MDM10 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria- endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: SWS_DROAN
Sequence: MDVLELLRASATGSYTALFSDAWCQYVSKQITNSMYLYCALGVLSMVFLAWFMYFKRLARIRLRDEASRSMSAVNSSSGGDLRGLRFRKRDKMLFYGRRMLRKMKNVSGQMYSSGKGYKRRAVMRFARRILQLRRDNMPLEMRTVEPPAEYLEETIDGSDRVPPDALYMLQSIRIFGHFEKPVFLRLCKHTQLLELMAGDYLFKITDPDDSVYIVQSGMINVYISNADGSTLSLKTVRKGESVTSLLSFIDVLSGNPSYYKTVTAKAIEKSVVIRLPMEAFEEVFQDNPDVMIRVIQVIMIRLQRVLFTALRNYLGLNAELVQNHMRFKSSTIMAPSTHSSQCSRQTGSQPTLGVPAPTCSNTTTTASPTTANTVHSGLAGANGVIGQSRPPISPSRHSREEHTLSDPNPNPDVINTSVGGASGTSMYAEVHGDAPNVDVFHQQQHSVGNLSTRRGSISQMAPDLGPALSQPGLGQGQGLGPGVTGAPPLMTGAPASKIDMRLVHASAVDSLRKELGLPEEDSHIIEPFVEVRELEPNVTLITEGNSDDVCVWFVMTGTLAVYQANQDAARAKQQQEKNDMLIHFVHPGEIVGGLAMLTGEASAYTIRSRNNSRVAFIRRAAIYQIMRQRPRIVLDLGNGVVRRLSPLVRQCDYALDWIFLESGRAVYRQDEISDSTYIVLSGRMRSVITHPGGKKEIIGEYGKGDLVGIVEMITETSRTTTVLAVRDSELAKLPEGLFNAIKLRYPIVVTKLISFLSHRFLGTMQTRSSSAAPGGPVEANPVTHKYSTVALVPITDEVPLTPFTYELYHSLCAIGPVLRLTSDVVRKQLGPNIFEAANEYRLTSWLAQQEDRNIITLYQCDNALSAWTQRCMRQADVILIVGLGNGSHLVGKFEREIDRLAMRTQKELVLLYPETTNSKPANTLSWLNARPWVTKHHHVLCVKRIFTRKSQYRINDLYSRVLLSEPNMHSDFSRLARWLTGNSIGLVLGGGGARGAAHIGMLKAIQEAGIPIDMVGGVSIGALMGALWCSERNITTVTQKAREWSKKMTKWFLQLLDLTYPITSMFSGREFNKTIHDTFGDVSIEDLWIPYFTLTTDITASCHRIHTNGSLWRYVRSSMSLSGYMPPLCDPKDGHLLLDGGYVNNLPGQLWRYCRASMSIAGVFPPFCDYRDGHLLLDGCYTNNVPADVMHNLGAAHIIAIDVGSQDDTDLTNYGDDLSGWWLLYKKWNPFTSPVKVPDLPDIQSRLAYVSCVRQLEEVKNSDYCEYIRPPIDKYKTLAFGSFDEIRDVGYVFGKNYFENMAKAGRLGRFNQWFNKEPPKRGNHASLNEYTFIDLAQIVCRLPETNAGNSADIFSEDEDCDGYISEPTTLNTDRRRIQVPRAGNSLSFSENEMDSDVELDLQLDRKTEKSIHSAATSVARGSMRSREFHKLEQDRSVEITRLKDETERIMAPTNLDRKGDGQEQEKEPEQEQELETEEPNQENTEVEEEQRNQGEGNEDNKENKGGAYNETKN
What is the function of this protein?
Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho).  This deacylation occurs at both sn-2 and sn-1 positions of PtdCho.  Its specific chemical modification by certain organophosphorus (OP) compounds leads to distal axonopathy.  Plays a role in the signaling mechanism between neurons and glia that regulates glia wrapping during development of the adult brain.  Essential for membrane lipid homeostasis and cell survival in both neurons and glia of the adult brain (By similarity).
What are the official names of this protein?
Neuropathy target esterase sws, Swiss cheese.
What is the protein family that this protein belongs to?
Belongs to the NTE family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=Sws tethers Pka-C3 to the membrane.
Protein: GCH11_NOSS1
Sequence: MTIASSNGSNRAQSPLITDLAEAINTRPDRNTHNGREPELHQPSEEDMESMMGAVRSILVGVGEDPEREGLLKTPKRVAEAMRFLTSGYNQSLEELLNGAVFDEGHNEMVLVRDINFFSLCEHHMLPFMGRAHVAYIPNQKVVGLSKLARIVEMYSRRLQVQERLTRQIAEAVQTILEPQGVAVVMEASHMCMVMRGVQKPGSWTVTSAMLGVFQEEQKTREEFFNLIRHQPAFF
What are the official names of this protein?
GTP cyclohydrolase 1 1, GTP cyclohydrolase I 1, GTP-CH-I 1.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: IWR1_YEAST
Sequence: MSTISTTTAPEFIRVKRRRDEDSVQALLIDEGKRVKKQKFIFKLSKTVSSESYQSEQESSTPLLKLAHEDHRHFVLEQRKKSRRDSDDEKSQQRLAAEGSTVDDDGLPPEINQMVNDYLKLNKGVEKTERKKPSRKYFTGDSAKIASLPSLDYVFDIYHLEKIHDDEVARYNNEKNIGFVKIIEHIDLALDEESDPNEARSDDEDSNDENYYQNDYPEDEDDDRSILFGSEGEDIAALGEEIVIGVNKSRFSSWNDDKIQGSNGYHDVEEEYGDLFNRLGGKSDVLKSINSSNFIDLDGQEGEIEISDNEDDSDEGDDIEYPRNEFFPTDVDDPLAHHRDRIFHQLQKKINRS
What is the function of this protein?
Directs RNA polymerase II nuclear import.  Binds RNA polymerase II in the active center cleft between the two largest subunits in the cytoplasm.  Then uses an N-terminal bipartite nuclear localization signal that may be recognized by karyopherin alpha to direct the polymerase II complex nuclear import.  In the nucleus, is displaced from polymerase II complex by transcription initiation factors and nucleic acids, enabling its export and recycling.
What are the official names of this protein?
RNA polymerase II nuclear localization protein IWR1, Interacting with RNA polymerase II protein 1.
What is the protein family that this protein belongs to?
Belongs to the IWR1/SLC7A6OS family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and cytoplasm.
Protein: HFLK_ECOLI
Sequence: MAWNQPGNNGQDRDPWGSSKPGGNSEGNGNKGGRDQGPPDLDDIFRKLSKKLGGLGGGKGTGSGGGSSSQGPRPQLGGRVVTIAAAAIVIIWAASGFYTIKEAERGVVTRFGKFSHLVEPGLNWKPTFIDEVKPVNVEAVRELAASGVMLTSDENVVRVEMNVQYRVTNPEKYLYSVTSPDDSLRQATDSALRGVIGKYTMDRILTEGRTVIRSDTQRELEETIRPYDMGITLLDVNFQAARPPEEVKAAFDDAIAARENEQQYIREAEAYTNEVQPRANGQAQRILEEARAYKAQTILEAQGEVARFAKLLPEYKAAPEITRERLYIETMEKVLGNTRKVLVNDKGGNLMVLPLDQMLKGGNAPAAKSDNGASNLLRLPPASSSTTSGASNTSSTSQGDIMDQRRANAQRNDYQRQGE
What is the function of this protein?
HflC and HflK help govern the stability of phage lambda cII protein, and thereby control the lysogenization frequency of phage lambda.  HflKC inhibits the SecY-degrading activity of FtsH, possibly helping quality control of integral membrane proteins.
What are the official names of this protein?
Modulator of FtsH protease HflK.
What is the protein family that this protein belongs to?
Belongs to the band 7/mec-2 family. HflK subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: RHMR_ECOLI
Sequence: MLESSKVPALTRAIDILNLIARIGPCSAATIIDTLGIPKSTAYLLLNELRRQRFLSLDHQENFCLWTRLVELSGHALSKMDLRELARPRLTQLMDTTGLLCHLGIIDNGSAYYILKVESSATISVRSHEGKSLSLYRSGIGKCLLAWQPAAVQQSIIEGLVWEQATPTTITHPQQLHEELARIRRQGWSYDNGEDYADVRCVAAPVFNANNELTAAISVVGTRLQINEEYRDYLAGKAIACARDISRLLGWKSPFDLQAS
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator RhmR.
Protein: PRP2_BOMMO
Sequence: MADVFESLELLFDRPNEPLITPKGENNSVFQLTEQFLTEDYANNGIELNNRFGDDASEKIPLKNLSKLPEFKIATQLPKDAEFSLFLPKHQEMANELLGVLMDVPENELQDLLSTCAFARVNLNPQLFNYCYSVALMHRRDTRKVRVKNFAEVFPSKFLDSQVFTQARETAAVIPPDVPRIPIIIPRDYTATDLEEEHRLAYWREDIGINLHHYHWHLVYPFTANDLSIVAKDRRGELFFYMHQQVIARFNCERLCNSLKRVKKFSNWREPIPEAYFPKLDSLTSSRGWPPRQSGMQWQDLNRAAEGLFVTIDEMERWRRNVEEAIATGTVRLPNGQTRPLDIDTLGNMLESSALSPNRELYGSIHNNGHSFTAYMHDPEHRYLEQFGVIADEATTMRDPFFYRWHAYIDDVFQKHKESAYVRPYTRSELENPGVQVRSVSVETPGGQPNTLNTFWMLSDVNLSRGLDFSDNGPVYARFTHLNYRHFSYRINVNNTGSSRRTTVRIFITPKFDERNVPWIFSDQRKMCIEMDRFVTVLNAGENNIVRQSTESSITIPFEQTFRDLSAQGNDPRRDELATFNYCGCGWPQHMLVPKGTEAGMPFQLFVMLSNYDLDRIDQDDGKQLTCVEASSFCGLKDKKYPDRRAMGFPFDRPSSSATSLQDFILPNMGLQDITIQLQNVTEPNPRNPPMSV
What is the function of this protein?
This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds.  Catalyzes the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and possibly 5,6 dihydroxyindole to indole-5'6 quinone.
What are the official names of this protein?
Phenoloxidase subunit 2, PO 2, Tyrosinase 2.
What is the protein family that this protein belongs to?
Belongs to the tyrosinase family.
What are the subcellular locations of this protein?
Secreted.
Protein: CYB6_PROHO
Sequence: MFTKQVQESGVYKWFNDRLEIEAISDDISSKYVPPHVNIFYCLGGITLVCFIIQFATGFAMTFYYKPSVTEAFTSVQYLMNEVSFGWLIRSIHRWSASMMVLMMILHVFRVYLTGGFKNPRELTWITGVILAVITVSFGVTGYSLPWDQVGYWAVKIVSGVPEAIPLVGPLMVELIRGSASVGQATLTRFYSLHTFVLPWFIAVFMLMHFLMIRKQGISGPL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetB subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: BRAP_HUMAN
Sequence: MSVSLVVIRLELAEHSPVPAGFGFSAAAGEMSDEEIKKTTLASAVACLEGKSPGEKVAIIHQHLGRREMTDVIIETMKSNPDELKTTVEERKSSEASPTAQRSKDHSKECINAAPDSPSKQLPDQISFFSGNPSVEIVHGIMHLYKTNKMTSLKEDVRRSAMLCILTVPAAMTSHDLMKFVAPFNEVIEQMKIIRDSTPNQYMVLIKFRAQADADSFYMTCNGRQFNSIEDDVCQLVYVERAEVLKSEDGASLPVMDLTELPKCTVCLERMDESVNGILTTLCNHSFHSQCLQRWDDTTCPVCRYCQTPEPVEENKCFECGVQENLWICLICGHIGCGRYVSRHAYKHFEETQHTYAMQLTNHRVWDYAGDNYVHRLVASKTDGKIVQYECEGDTCQEEKIDALQLEYSYLLTSQLESQRIYWENKIVRIEKDTAEEINNMKTKFKETIEKCDNLEHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRANQVLLQNKLKEEERVLKETCDQKDLQITEIQEQLRDVMFYLETQQKINHLPAETRQEIQEGQINIAMASASSPASSGGSGKLPSRKGRSKRGK
What is the function of this protein?
Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein.  Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation.  May also act as a cytoplasmic retention protein with a role in regulating nuclear transport.
What are the official names of this protein?
BRCA1-associated protein, BRAP2, Impedes mitogenic signal propagation, IMP, RING finger protein 52, RING-type E3 ubiquitin transferase BRAP2, Renal carcinoma antigen NY-REN-63.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DID_ATHCH
Sequence: MIQVLLVIICLAVFPYQGSCIILESENVNDYEIVYPKKLTVLPTGAMNSPHPCCDPVTCKPKKGEHCISGPCCRNCKFINSGTICKKARGDDMNDYCTGTTPDCPRNPYKD
What is the function of this protein?
Inhibits ADP-induced platelet aggregation in human platelet-rich plasma (IC(50) is 6 uM).
What are the official names of this protein?
Disintegrin DS-AC.
What is the protein family that this protein belongs to?
Belongs to the disintegrin family. Dimeric disintegrin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: F16PA_SHIFL
Sequence: MKTLGEFIVEKQHEFSHATGELTALLSAIKLGAKIIHRDINKAGLVDILGASGAENVQGEVQQKLDLFANEKLKAALKARDIVAGIASEEEDEIVVFEGCEHAKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRVTPVGTPVTEEDFLQPGNKQVAAGYVVYGSSTMLVYTTGCGVHAFTYDPSLGVFCLCQERMRFPEKGKTYSINEGNYIKFPNGVKKYIKFCQEEDKSTNRPYTSRYIGSLVADFHRNLLKGGIYLYPSTASHPDGKLRLLYECNPMAFLAEQAGGKASDGKERILDIIPETLHQRRSFFVGNDHMVEDVERFIREFPDA
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBB_TACAC
Sequence: MVHLSGSEKTAVTNLWGHVNVNELGGEALGRLLVVYPWTQRFFESFGDLSSADAVMGNAKVKAHGAKVLTSFGDALKNLDNLKGTFAKLSELHCDKLHVDPENFNRLGNVLVVVLARHFSKEFTPEAQAAWQKLVSGVSHALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: CSHE_BACCR
Sequence: MVYLKNFLELGISETFNHTLRENGITEATPIQEKAIPVILSGKDIIGQAKTGTGKTLAFVLPILEKIDPECSDVQALIVAPTRELALQITTEIKKMLVQREDINVLAIYGGQDVAQQLRKLKGNTHIVVATPGRLLDHIRRETIDLSNLSTIVLDEADQMLYFGFLYDIEDILDETPGSKQTMLFSATMPKDIKKLAKRYMDEPQMIQVQSEEVTVDTIEQRVIETTDRAKPDALRFVMDRDQPFLAVIFCRTKVRASKLYDNLKGLGYNCAELHGDIPQAKRERVMKSFREAKIQYLIATDVAARGLDVDGVTHVFNYDIPEDVESYIHRIGRTGRAGGSGLAITFVAAKDEKHLEEIEKTLGAPIQREIIEQPKIKRVDENGKPVPKPAPKKSGQNRQRDSREGSRSDSRRDSRNSSRSDSRNSSRNSSRNENNRSFNKPSNKKGSTKQGQQRRGR
What is the function of this protein?
DEAD-box RNA helicase.  Probably has an RNA-dependent ATPase activity and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short RNA duplexes (By similarity).
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase CshE.
Protein: RS12_LEPIC
Sequence: MPTISQLIRHGRQKQKKRTKSPALKSSPQRRGVCTRVMTFTPKKPNSALRKVARVRLTTGIEVTAYIPGEGHNLQEHNVVLIRGGRVKDLPGVRYHIIRGTLDTLGVDKRRNGRSKYGAKRPKA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: SECG_PYRIL
Sequence: MARRRKYEGLNPFVAAGLIKFSEEGELERIKLNPRTAILVSITVIIAILVLNILHPL
What is the function of this protein?
Involved in protein export.  The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex.
What are the official names of this protein?
Preprotein translocase subunit SecG, Protein transport protein Sec61 subunit beta homolog.
What is the protein family that this protein belongs to?
Belongs to the SEC61-beta family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.