PharMolix/UniProtQA huggingface dataset:
Protein: TRPD_RUTMC
Sequence: MNIQQAIKQIIKKQDLSENEMHKVMNDIMTGKTTDAQIGGFLVGLAIKGESVDEITAAAKTMRSLVKSVTIKNTKHLVDTCGTGGDGLGLFNISTACTFVVAAAGGSVAKHGNSSISSKSGSADVLKAAGVNLDMSVEKISKCIEKIGIGFMFAPFHHIAMKHVIEPRKDLAIKTIFNVLGPLTNPAKVPNQVMGVYAQSLVEPIAYVLKNLGSKHVIVVHSKDGLDEISIADDTFVAELKNGQVSTYTINPADFSLPLGNLNDIKANNADYSLVLIQQALDGKDGVAKNIIALNSGAAIYVCGLANSLQKGVNKALNILNSDVAHQKLDDFVRESTDC
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: SYI_META3
Sequence: MKEIKGKVDFREMDKEIKEFWENNEIYQKVKKLNENYPDYYFVDGPPYCSGSIHLGTAWNKTIKDTVLRFKRMQNYNVLDKAGWDMHGLPIEVKVEHEFNLQSKKDIETKVGTDVFIEKCKEFALNNKEVMENQFKNLGIWLDWENAYLPIKNDYIEAGWWSLKRAHEKELLSKDLRVGYWCPRCETSLAEHEVRGEYQDVLDPSVYVKFKVADDNSYPNTYFVIWTTTPWTLISNLLIAVNPEFDYGFVEVIFDNERKETWVIAEALVEAVIKLAKKQNNIKSYNIVKKVKGKELEGIKYVPALLEENERQKEFFQLEKVHTIVLGEHVSLDGGTGLVHTAPGFGEEDFEVGKKYNSPIYSPIDDEGKYVEGKWKGVFVKDADEDIIATLTDKNLIVNAGKKKHTYPHCWRCKTPLLFRSTEQWFLNISKIKNNIVEHAKNTDWVPNWVETRYINGVKFVGDWNISRQRYWGIPLPIWICENKDCGKYKIIGSVEELKQEMINDIPINDDLHKPTVDKIIMKCDCGCEMKRTPDVLDVWYDSGLAPYASINAKELKKADFIVEGNDQVTKWFYSQHALSEIVFDDIPYKKCMMHGFTLDETGEKMSKSIGNVVNPDDVVEEFGADLLRFYLLSANKAWEDLRFSIGEMNDVKSVFNTLWNSYSFAVNYMVLDDFSPNEEYFNYLRDEDKWIISKINSLTKEAIEVLEIPHLHEYTWKVRDFILNDLSRWYIKLIRNRTWMEKEDPDKLSAYQTLYYVLMKLVVILAPVAPHISEKIYQNLKIEGMPQSIFMTKIVVEEEYINKEVEEGIETAREIVDAILKGRDKVKYTLRYPISKIILPNELGDIVNKYHYIIKEQGNVKNIEVKEFEGNISLKPNFRTLGASFKSDVPAVVKILNSQNPKELKDKLAEGEITIDGFTIKPEHVEFKIDIPDNIVGMELRKGSVYIDIELTEEIIKDGLKREVIRRIQSMRKDMDLDIEEKIKITMEGIEFNEDALKDIEKEVRGTFEPTIECDNIQEWNIKTPNGEVYNLKIGVKKN
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AKAP4_MOUSE
Sequence: MIAYCGTTTMSDDIDWLHSRRGVCKVDLYSPKGQQDQDRKVICFVDVSTLNVEDKDSKGAAGSRSEGELNLETLEEKEIIVIKDTEKQDQSKTEGSVCLFKQAPSDPISVLNWLLNDLQKYALGFQHALSPSASSCKHKVGDLEGDYSKIPSENCYSVYADQVNFDYLNKGPQNLRLEMAASKNTNNNQSPSNPATKSPSNQRSVATPEGECSMDDLSFYVNRLSSLVIQMARKEIKDKLEGGSKCLHHSMYTSGDKGKTSPRSAVSKIASEMAHEAVELTSSEMRGNGEDCRDGRKTFLYSEMCNKNKCGEKQQMCPKDSKEFADSISKGLMVYANQVASDMMVSVMKTLKVHSCGKPIPACVVLKRVLLKHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNHGKQNAADIMEAMLKRLVSALLGEKKETKSQSLAYATLKAGTNDPKCKNQSLEFSAMKAEMKGKDKCKSKADPCCKSLTSAERVSEHILKESLTMWNNQKQGNQGKVTNKVCCTSKDEKREKISPSTDSLAKDLIVSALMLIQYHLTQQAKGKDPCEEECPGSSMGYMSQSAQYEKCGGGQSSKSLSMKHFETRGAPGPSTCMKENQLESQKMDMSNMVLSLIQKLLSESPFSCDELTESDNKRCCDPRSSKAAPMAKRPEEQCQDNAELDFISGMKQMNRQFIDQLVESVMKLCLIMAKYSNNGAALAELEEQAALVGSGSRCGRDAMMSQNYSETPGPEVIVNNQCSTTNLQKQLQAVLQWIAASQFNVPMLYFMGDDDGQLEKLPEVSAKAAEKGYSVGDLLQEVMKFAKERQLDEAVGNMARKQLLDWLLANL
What is the function of this protein?
Major structural component of sperm fibrous sheath.  Plays a role in sperm motility (PubMed:12167408).
What are the official names of this protein?
A-kinase anchor protein 4, AKAP-4, A-kinase anchor protein 82 kDa, AKAP 82, mAKAP82, FSC1, Major sperm fibrous sheath protein, Protein kinase A-anchoring protein 4, PRKA4, p82.
What is the protein family that this protein belongs to?
Belongs to the AKAP110 family.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum. Note=Localizes to the principle piece of the sperm flagellum.
Protein: COQ4_MOUSE
Sequence: MATLLLLRSLRLHRSLRPRTRPAVDVPLRAGSHGARLLYPDHIPTTPLQKMLLAAGAAGMALYNPYRHDMVAVLGETTGCHTLKFLRDQMKKDPEGAQILQERPRISLSTLDLSKLQSLPEGSLGREYLRFLDVNKVSPDTRAPTRFVDDEELAYVIQRYREVHDMLHTLLGMPTNMLGEVVVKWFEAVQTGLPMCILGALFGPIRLRTQSLQVLFSELIPWAIQNGRRAPCVLNIYYEQRWEQPLTALREELGISPPPKHIQGLA
What is the function of this protein?
Component of the coenzyme Q biosynthetic pathway.  May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis.  Required for steady-state levels of other COQ polypeptides.
What are the official names of this protein?
Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial, Coenzyme Q biosynthesis protein 4 homolog.
What is the protein family that this protein belongs to?
Belongs to the COQ4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: CROCC_CAEEL
Sequence: MKSAASSEDVVRVTEDLSECRNRLDAGIEENRRNRQVIQDINDQLQRFRQRANAESIESFNLTPSPDVTLSSLAHPGLTHLHNQTNISMPSLTIDIPLNSNAMISSSRTPNYAINGLRNRHKSLVGHRYRSTSPIGDYGRHRSSPRVLAHYNLDGADIGVGEENLDELFAKLKEELFKNNTLEEVNEMLREENDAALAANEHLRVDATNLSRQLQQLQQQQHTESMRFRSENTRYRNQTETQHRKLISLWKEFTAVKRQLHELRTTTANDLDRQLTEFTRCATLMRKAIRHAEQKNLDQKEQMKREKDDVLDETLRQLNSVTENYMKSEEKANERQRDLKRKEDECRKLREQNDELSDILEQLSKMAHEMAGGRGRNETPMDVARKMRKLLTTKNGEIDESREAAKQAEKERDRAKKDLEKEEKRRKDDREAERKRSSVYSQREHDLKKLDDELRKASEKIRNLEEQRESQEKLTISVQNSLNEAHRQHKQFIEELMIRHREELKEREDSHEEALRSKDTEERSRFEKERSEREKIRRESDELRETQRSLKGDVAAMKTDLDDKTLRLDMLETERDELKKKLETEREQADQRDLEIAECRAKLDEMAEKEAELRKELAEFQAIITAMEGEGKLNQEQFLESKNELNTLTDQIESLNSEVENKNEEIRNLMATLQEKEVHIQNVRTSSHQLTATYEEANGEIDILKAELTRLHEQVNERTRQISEANEKYDDAARKNDALLEDVATWQEKYEQLKMELEEMNRRGQEKEREEADLRALLDDLRGNFDKLTNELKQKGVTVDSLNEEISSLKEQLNKSEKERKEELLRMEELEQKNEAEMKEEYEVKLQLAEKDRQGVENFGKECEARMNELTKIHEMLMEEHDQLKVDHLHTEEEVERLKEKMRKELEKLNEQNDGDRAEWSNERNRLESSKNEAVTELQERVQKLEDVVKEKEDKEIALRRDLEDSHEKSRDLDDKLRKMELTDEEKEEDRKKEQKTLNEERMKLMEQKEEAMLVATKHATTIDQQTRRISVLEGDVEKLTAGIAERESSINALESNTMELISKLETTEAELEKLKDELAVMLKQNSELKNGKEGLSEKWNEERKKIQDLADQLREANKVVHNMRMKNVNLEEKKNELDQNVTDLTNKVRQLEIQLMDKAAKNEVSGDLLRKMEHDAQSMLKQAQNEQFRLTDLEKVRKALQDENQRLVNDLATVKAAFEVKRETSKSAISDILDKYRSAEEKANKGELDNQRLRSDLATVTLKLERQELKAKDSDNRLRDSQKRFEEVQSKLANLQKSAVESLQNPMSSNSRQNRSIYVDIPRAASSIGLNENSDEVPLRSSPSVRFADSSQNMQRAVDSMDVSSSVGVTLRFLKERIEQLEADNADLSDALEKAKDELRQRNEKLADRQMVIERVERQLVHITEERNTIENRMTSQRQMYLTNEESSRSREHEIRSMKARISTLELHLREKESKLAHLRKEIEVLHGQLHDALESKEKATGLVGVQDSKHRDLEEQLDRANRERELAIGKQRRTLAENENLFRKLEQLEKEREQLMREITDERRLNERNRTSLEELRVSERTWKSAMTTAKKPAEEQERAVQEQRRWEESNHEMTNRNTALTKECDRLRVEMRDQLNRMNGINLRSVDFERKNEELSSKLIVMQNTVTAMKKFEEEWKRLEAEMRAELKILRKEKLMQTAEIEDLKRKSFRSDTEKKEIEGIRVRLEREISALKRHVDALEEEKGKTEKAVRETMNERRAIDKSLASMERENQQLYRNCAQLQAQIQNLERDAGNRSVTKLAKEHSLLEARIAALIEEKRQLQSMLDQKDANYSHKRKLLESQIQLLREQLEAERRKRTKGVVATGPTVSRRGVQHTSAFRHTIERHRSLSQSSERTILQERYLEYVYTGDRTPAIQMINTPPISPLSHSGSFNSDGREARIRRESDNGHLQH
What is the function of this protein?
Major structural component of the ciliary rootlet, a cytoskeletal-like structure in ciliated cells which originates from the basal body at the proximal end of a cilium and extends proximally toward the cell nucleus (PubMed:24094853).  Required for cilia integrity and function in sensory neurons (PubMed:2428682, PubMed:17314406, PubMed:24094853).  Maintains cilia integrity, partly by modulating the assembly and transport of intraflagellar proteins along the ciliary axoneme (PubMed:24094853).  Required for normal mating behavior and normal responses to environmental and chemical stimuli (PubMed:2428682, PubMed:17314406, PubMed:24094853).
What are the official names of this protein?
Rootletin, Abnormal dye filling protein 14, Chemotaxis abnormal protein 10.
What is the protein family that this protein belongs to?
Belongs to the rootletin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, cilium axoneme.
Protein: CDPK7_ORYSJ
Sequence: MGNQCQNGTLGSDYHNRFPREHAVGYVQGDSYLDLKKFDDTWPEVNNFKPTAASILRRGLDPTSINVLGRKTADLREHYIIGRKLGQGQFGTTYLCTEINTGCEYACKTIPKRKLITKEDVEDVRREIQIMHHLSGHKNVVAIKDVYEDGQAVHIVMELCAGGELFDRIQEKGHYSERKAAELIRIIVSIVAMCHSLGVMHRDLKPENFLLLDKDDDLSIKAIDFGLSVFFKPGQVFTELVGSPYYVAPEVLHKRYGPESDVWSAGVILYVLLSGVPPFWAETQQGIFDAVLKGHIDFQSDPWPKISDSAKDLIRKMLSHCPSERLKAHEVLRHPWICENGVATDQALDPSVISRLKQFSAMNKLKKLALRVIAERLSEEEIAGLREMFKAVDTKNRGVITFGELREGLRRFGAEFKDTEIGDIMEAAHNDNNVTIHYEEFIAATLPLNKIEREEHLLAAFTYFDKDGSGYITVDKLQRACGEHNMEDSLLEEIISEVDQNNDGQIDYAEFVAMMQGSNVGLGWQTMESSLNVALRDAPQVH
What is the function of this protein?
May play a role in signal transduction pathways that involve calcium as a second messenger (By similarity).  May be a signaling component in the response to gibberellin and cold stress (PubMed:15604699).
What are the official names of this protein?
Calcium-dependent protein kinase 7, OsCDPK7, OsCPK7, Calcium-dependent protein kinase OsCDPK1, Calcium-dependent protein kinase OsCDPK13, Calcium-dependent protein kinase isoform 11, OsCPKII.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily.
What are the subcellular locations of this protein?
Membrane; Lipid-anchor. Cytoplasm, cytosol.
Protein: GLYA_META3
Sequence: MNPSEVQQFVRETALKQHNWMRECIKLIASENITSIPVREACATDFMHRYAEGLPNNRLYQGCEYIDDIENLCIELSEDIFKAEHANVQPTSGVVANLAVFFAEAKPGDKLMAMDVPNGGHISHWKVSAAGIRGLRASAHPFDAEEMNIDVDKMVKQILEEKPRLVLFGGSLFPFPHPVKDAVDAANEVGATIAYDGAHVLGLIAGGQFQDPLREGAEYMMGSTHKTLFGTQGGVVLTEKKNAKKIDDKIFPGVVSNHHLHHKAGLAIALAETKEFGEAYAKQVVKNAKALGQALYERGCNVLCEHKGFTESHQVILDIEKSECIEFSARELATMFEEANIILNKNLLPWDDVSNSDNPSGIRLGSQECTRLGMKESEMDEIAEFMKRIAIDGEDIKKVKEDIVEFAKSYSEIHYAFEGGDAFKYLKFY
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydromethanopterin (H4MPT) serving as the one-carbon carrier.  Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCST1_HUMAN
Sequence: MDIKHHQNGTRGQRRKQPHTTVQRLLTWGLPVSCSWFLWRQPGEFPVTALLLGAGAGGLLAIGLFQLLVNPMNIYEEQKIMFLYSLVGLGAMGWGTSPHIRCASLLLVPKMLGKEGRLFVLGYALAAIYVGPVANLRHNLNNVIASLGCTVELQINNTRAAWRISTAPLRAMFKDLLSSKELLRAETRNISATFEDLDAQVNSETGYTPEDTMDSGETAQGREARQAPASRLHLSTQKMYELKTKLRCSYVVNQAILSCRRWFDRKHEQCMKHIWVPLLTHLLCLPMKFKFFCGIAKVMEVWCRNRIPVEGNFGQTYDSLNQSIRGLDGEFSANIDFKEEKQAGVLGLNTSWERVSTEVRDYVYRQEARLEWALGLLHVLLSCTFLLVLHASFSYMDSYNHDIRFDNIYISTYFCQIDDRRKKLGKRTLLPLRKAEEKTVIFPCKPTIQASEMSNVVRELLETLPILLLLVVLCGLDWALYSIFDTIRHHSFLQYSFRSSHKLEVKVGGDSMLARLLRKTIGALNTSSETVMESNNMPCLPQPVGLDARAYWRAAVPIGLLVCLCLLQAFGYRLRRVIAAFYFPKREKKRILFLYNDLLKKRAAFTKLRRAAILRRERQQKAPRHPLADILHRGCPLLRRWLCRRCVVCQAPETPESYVCRTLDCEAVYCWSCWDDMRQRCPVCTPREELSSSAFSDSNDDTAYAG
What is the function of this protein?
E3 ubiquitin-protein ligase which mediates 'Lys-48'-linked ubiquitination of STAT2 and induces its proteosomal degradation thereby negatively regulating type-I-interferon signaling.  Essential sperm cell-surface protein required for sperm-egg fusion and fertilization (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase DCST1, DC-STAMP domain-containing protein 1, RING-type E3 ubiquitin transferase.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS6_PSEPK
Sequence: MRHYEIIFLVHPDQSEQVGGMVERYTKLIEEDGGKIHRLEDWGRRQLAYAINNVHKAHYVMLNVECTGKALAELEDNFRYNDAVIRNLVIRRDEAVTGQSEMLKAEENRSERRERRERPEHADSAEGDDSNDSDSSDNADE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: GBGE_DROME
Sequence: MDPSALQNMDRDALKKQIENMKYQASMERWPLSKSIAEMRSFIEENEKNDPLINAPDKKNNPWAEKGKCVIM
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems.  The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.  This subunit functions in visual transduction in the compound eye.
What are the official names of this protein?
Guanine nucleotide-binding protein subunit gamma-e, Ggamma(e).
What is the protein family that this protein belongs to?
Belongs to the G protein gamma family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: MTAP_SYNYG
Sequence: MGMIISMAMTAVTIWTKTKPGRVSCFIRKNSTMVNAPIGIIGGSGLYQMEALKNVEEVTLDTPFGAPSDSFIVGELAGVRVAFLARHGRGHHLLPSEIPFRANIHGMKQLGVKYLISASAVGSLQAEAKPLDMVVPDQFIDRTRQRISTFFGEGIVAHIGFGNPICPQLAQCLSTAIAGLELEGVTLHDRGTYVSMEGPAFSTIAESNLYRSWGGTVIGMTNLPEAKLAREAEIAYATLALVTDYDCWHPDHDHVTVEMVIGNLQKNAVNAQQVILETVKQLAANPFESIAHRALQYAVLTPPDKFPAATYEKLSLLLGKYYPPAP
What is the function of this protein?
Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate.  Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis.  Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine.  Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
What are the official names of this protein?
S-methyl-5'-thioadenosine phosphorylase, 5'-methylthioadenosine phosphorylase, MTA phosphorylase, MTAP.
What is the protein family that this protein belongs to?
Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
Protein: HXB3_MOUSE
Sequence: MQKATYYDNTAAALFGGYSSYPGSNGFGYDGPPQPPFQAATHLEGDYQRSACSLQSLGNAAPHAKSKELNGSCMRPGLAPEPLPAPPGSPPPSAAPTSTTSNSNNGGGPSKSGPPKCGAGSNSTLTKQIFPWMKESRQTSKLKNSSPGTAEGCGGGGGGGGGGGGGGGGSSGGGGGGGGGGDKSPPGSAASKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKKDQKAKGLASSSGGPSPAGSPPQPMQSTAGFMNALHSMTPSYDSPSPPAFGKGHQNAYALPSNYQPPLKGCGAPQKYPPTPASEYEPHVLQANGGAYGTPTMQGSPVYVGGGGYADPLPPPAGPSLYGLNHLSHHPSGNLDYNGAAPMGPNQHHGPCDPHPTYTDLSSHHAPPQGRIQEAPKLTHL
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-B3, Homeobox protein Hox-2.7, Homeobox protein MH-23.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PNCB_ECOHS
Sequence: MTQFASPVLHSLLDTDAYKLHMQQAVFHHYYDVHVAAEFRCRGDDLLGIYADAIREQIQAMQHLRLQDDEYQWLSALPFFKADYLNWLREFRFNPEQVTVSNDNGKLDIRLSGPWREVILWEVPLLAVISEMVHRYRSPQADVAQALDTLESKLVDFSALTAGLDMSRFHLMDFGTRRRFSREVQETIVKRLQQESWFVGTSNYDLARRLSLTPMGTQAHEWFQAHQQISPDLANSQRAALAAWLEEYPDQLGIALTDCITMDAFLRDFGVEFASRYQGLRHDSGDPVEWGEKAIAHYEKLGIDPQSKTLVFSDNLDLRKAVELYRHFSSRVQLSFGIGTRLTCDIPQVKPLNIVIKLVECNGKPVAKLSDSPGKTICHDKAFVRALRKAFDLPHIKKAS
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: NPTX1_MOUSE
Sequence: MLAGRAARTCALLALCLLGSGAQDFGPTRFICTSVPVDADMCAASVAAGGAEELRSNVLQLRETVLQQKETILSQKETIRELTTKLGRCESQSTLDSGPGEARSGGGRKQPGSGKNTMGDLSRTPAAETLSQLGQTLQSLKTRLENLEQYSRLNSSSQTNSLKDLLQSKIDDLERQVLSRVNTLEEGKGGPKNDTEERAKIESALTSLHQRISELEKGQKDNRPGDKFQLTFPLRTNYMYAKVKKSLPEMYAFTVCMWLKSSAAPGVGTPFSYAVPGQANELVLIEWGNNPMEILINDKVAKLPFVINDGKWHHICVTWTTRDGVWEAYQDGTQGGNGENLAPYHPIKPQGVLVLGQEQDTLGGGFDATQAFVGELAHFNIWDRKLTPGEVYNLATCSSKALSGNVIAWAESQIEIFGGATKWTFEACRQIN
What is the function of this protein?
May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses.
What are the official names of this protein?
Neuronal pentraxin-1, NP1, Neuronal pentraxin I, NP-I.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle.
Protein: NU4M_LYCSM
Sequence: MLKITFMTMMLIPTTLILKPKMLYQTTTSYSFMIALFSLSLLEPNSNTYLHLDSTSAPLLLLSYWLMPMTMMASQHAMNKEPLQRQRTFLSILTLLQLFISLTFMASNITLMYIMFEATLIPTLIIITRWGQQTERLTAGTYFMMYTLTTSMPLLTAILFINNTTNTPTLFMQMMQTTSPWTELMLWIACLGAFLAKMPVYGLHLWLPKAHVEAPIAGSMVLAAILLKLGGYGIIRMTQILPTMKTDLFLPFIVLSLWGATLANLTCLQQTDLKSLIAYSSVSHMGLVIAATMIQTQWSLSGAMALMIAHGFTSSALFCLANTTYERTKTRIMILTRGFHSILPMITTWWLMTNLMNIATPPSINFTGELLIASSLFNWCPTTIILFGLSMLITASYSLHMLLSTQTGTPTLNMVTYPTHSREHLLMVLHILPLMLISLKPELII
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: SYI_TERTT
Sequence: MTDYKSTLNLPQTSFAMKANLAQREPQTLKRWQKENLYQQIRQARAGREKFILHDGPPYANGEIHIGHAVNKILKDIIVKAKTLSGFDAPYIPGWDCHGLPIEHNVEKKVGKAGVKVDFATFRKKCREYAAKQVAGQKEGFVRLGVLADWDKPYLTMDYKTEADIVRALGKIVANGHLVRGFKPVYWSVVGGSALAEAEVEYQEKTSFSIDVKYAVKDEADFTQRVAELGGEGPVSVVIWTTTPWTLPSSQAVSLNADLEYVVVQQPGARLLVAEALLESVGKRAGIDTATIVGRCHGRDLENLVLQHPFYTREVPVILGDHVTTDAGTGCVHTAPDHGMEDFEVGSRYGIGTLNYVDENGLYRESVEIFAGDHVYKVDEKIIELLESRDALLHQEKFTHSYPHCWRTKTPLIFRATPQWFISMTKNGLLDTVKTAVDGVEWIPDWGEARMRSMLEASPDWCISRQRTWGVPIALFVHKETQDLHPDTPALVEKVAALIETDGMDAWFNLNPEEILGEDAANYSKVTDTLDVWFDSGVTHYSVIQQREELQYPADLYLEGSDQHRGWFQSSLKTAIAINGTAPYKQVLTHGFTVDANGKKMSKSIGNTVSPQKVMNELGADVLRLWVAATDFSGDMSVSDEILMRTADSYRRIRNTMRYFMSNLNGFDPAINSVAFDDMVALDRWAVDRAAKLQRDIVACYDSYQFHTIYQKIHNFCIVDMGGFYLDIIKDRVYTMQEDSRARRSAQTAQYLIVQALVRWIAPILSFTADEIWQALPGEKTGPVFVAEWLELPELSEDDALNNSYWQTAAKVKTAVNKVLESKRSSGVIGGSLGAEVTLYASDELHAKLNSLGEELRFVLLVSAVNLKKLDEAPEDADQVDVVGLKVAVTKSEAAKCARCWHQRDDVGSHSEHPELCGRCVSNVEGNGEVRHYA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRIP1_MOUSE
Sequence: MPKCPKCDKEVYFAERVTSLGKDWHRPCLKCEKCGKTLTSGGHAEHEGKPYCNHPCYSAMFGPKGFGRGGAESHTFK
What is the function of this protein?
Seems to have a role in zinc absorption and may function as an intracellular zinc transport protein.
What are the official names of this protein?
Cysteine-rich protein 1, CRP-1, Cysteine-rich intestinal protein, CRIP.
Protein: RS8_PSECP
Sequence: MTMTDPVADMLTRLRNANSAYHDSVSMPYSKLKARVADILKAEGFIAGWKEEDAEVGKKLTLDLKFGPNRERSIAGVRRISKPGLRVYAKSTNLPHVLGGLGIAILSTSSGLLTDKQAGKKGVGGEVLAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: SYE_CLAMS
Sequence: MTETTAHPVTTATGTDVRVRFCPSPTGTPHVGLIRTALFNWAYARHTGGKLVFRVEDTDAARDSEESYEQLIEALRWLEIDWDEGEGVGGPHAPYRQSQRTDLYLDVIAKLTASGHLYESFATAEEIEARNRAAGRDPKMGYDNFERDLTEEERQAFRDEGRSPALRLRVPDTDLSFDDLVRGTVTFPAGSFPDFVLVRPNGAPLYTLVNPVDDALMGITHVLRGEDLLSSTPRQIALYHALIDIGVADAIPRFGHLPYVMGEGNKKLSKRDPESNLFHHRDRGFIPEGLINYLALLGWSLTHDRDVFSRMEMVTAFDVADVNPNPARFDLKKAESLNGDHIRLLALDDFAQRLVPYLQAADVVGAELTHDQRRMLEAAAPLVQERMQLLGEAPDLLSFLFTTADELPYDDAAVQALKDDAPEVLAASRGALSGVPHTQWDIDLVQEVLQNTLITGMGMKPRLAYGPLRVGISGRRISPPLFESMVLLGKDETIARLDRLAGMLGE
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1003_ARCFU
Sequence: MDLLRTEFDIQHHLVLSRKDTLHHALIRMIVSTLSTPEELTNLRKKDFRFNKGKNLDYYTVKLSEGGRSRISPVDKRTFEIIQTMPSQPFRMSEEEMNEIVRSYSPPGRIYTCKKLREAVESILSDSDLFGVKLRNDEERYAFMLDFNPLYSGLWDLEDEEGVEDFILSYSEVTGSRDWRKISDETGIEAEIVKKVIESGKKSILRFRADF
What are the official names of this protein?
Uncharacterized protein AF_1003.
Protein: SYE_NITMS
Sequence: MDEEIKHEIRKMALQNAFEHGGQTQDKIILGKILGTKPEFRTKVKEISGEISEIVASVNQLSPEEQQKEMEEKFPEALAPKEKIEEREGLPELKDAIQGKVVTRFPPEPNGYPHIGHAKAAIINSEYAKMYGGKFILRMDDTNPEAERMEYHAAIKVGLEWLGIEFDQVKSTSDDMEVFYEKGIELINSGKAYVCTCKREDISQNRRERKACKCSMEDVGKNNKNWEKMQNKFKPGEAIVRFRGDMKADNAVMRDPVLLRIIDEKHYTVGDKYRIWPSYDFAVAIEDSIDGVTHAFRSKEFELRKELIDAILDALGMRKPQQGFFSRLEFKGMPISKRIIKPLIEEGKVSWYDDPRLPTLEALRRRGIKPEAIRKFIMSLGLTKANTLAPFDALEAFNRKFVDADSMRLFMVKNAKKLKIKNLQSTIVEVPNHPINDLGKRKIEITEDFYISGDDSEAIKEQSTIRLLGLGNVKITKIGNELEGEFERDGDSSNILKIQWVPQKTAHEIKMIIPKILFNDEEFNEDSLEELDVYTEPQYLQLKEGEEIQFVRFGYCRKDSQNQAIFTHK
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EPMA_ECO24
Sequence: MSETASWQPSASIPNLLKRAAIMAEIRRFFADRGVLEVETPCMSQATVTDIHLVPFETRFVGPGHSQGMNLWLMTSPEYHMKRLLVAGCGPVFQLCRSFRNEEMGRYHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCPAAESLSYQQAFLRYLEIDPLSADKTQLREVAAKLDLSNVADTEEDRDTLLQLLFTFGVEPNIGKEKPTFVYHFPASQASLAQISTEDHRVAERFEVYYKGIELANGFHELTDAREQQQRFEQDNRKRAARGLPQHPIDQNLIEALKVGMPDCSGVALGVDRLVMLALGAETLAEVIAFSVDRA
What is the function of this protein?
With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P) on 'Lys-34'.  Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of EF-P 'Lys-34'.
What are the official names of this protein?
Elongation factor P--(R)-beta-lysine ligase, EF-P--(R)-beta-lysine ligase, EF-P post-translational modification enzyme A, EF-P-lysine lysyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.