PharMolix/UniProtQA huggingface dataset:
Protein: UBIE_PSEFS
Sequence: MTDQRKGSDAEPTTHFGFKNVPESQKAEKVAEVFHSVAAKYDLMNDVLSGGMHRLWKRFTIELSGVRTGNRVLDIAGGTGDLAAKFSKLVGPTGQVVLADINGSMLKVGRDRLLDKGVAGNIEFVQADAEKLPFPDNHFDCVTIAFGLRNVTHKEDAIRSMLRVLKPGGRLLVLEFSKPTNALMSKVYDTYSFAFMPLMGKLITNDAESYRYLAESIRMHPDQETLKSMMVEAGFDRVTYHNMTSGIVALHRGIKP
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: SYA_LACLS
Sequence: MKTMTSAEVRQMFLDFFKSKGHTVEPSQSLVPVNDPTLLWINSGVATLKKYFDGSVVPENPRLTNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRNEAIAFAWELLTSSEWFEFPAEKLYITYYPADKDTYNRWVEVGVDPTHLVPIEDNFWEIGAGPSGPDTEIFFDRGEIYDPEHVGLKLLAEDIENDRYIEIWNIVLSQFNANPAIPRSEYPELPQKNIDTGMGLERMVCIIQGGKTNFDTDLFLPIIREIEKLSGITYSPDSENMSFKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRAVMHGKKLGIQGKFLASLVPTVGKIMQSYYPEVLEKEDFIMQIIDREEETFNRTIDAGQKLIDELLVNLKAEGKDRIEGADIFRLYDTYGFPVELTEELAEDEGFKIDHEGFKVAMKAQQDRARAAVVKGGSMGAQNETLSSIEVDSKFLYEDKKSQAKLLVAIKDDELVDEVTGKAQLVFDVTPFYAEMGGQVADHGVIKNADGQEVATVLDVQHAPHGQNLHSVETTSPLKVGETYTLEIDEERRSAVVKNHTATHLLHAALHNIVGNHALQAGSLNEVEFLRFDFTHFAQVTKEELAEIERQVNEVIWQSLKVETIETDIATAKEMGAMALFGEKYGKNVRVVKIGDYSIELCGGTHTQTTSQIGLFKIIKEEGIGSGVRRIIAVTGQKAYEAFKDAENTLSEVAGLVKAPQASQIVAKVSNLQDELKAAQKENDALAGKLAASQSDEIFKNVQRAGSVSFIASQVTVPDANGLRNLADIWKQKELSDVLVLVATIGEKVSLLVASKSSDVKAGNLVKELAPFVDGRGGGKPDMAMAGGSNAAGIPELLTAVAEKLG
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CWC22_CRYNB
Sequence: MPRSLSRSVSPRPRSPSLSPPRPDSRSSRGRSLTPDDIPAYKRKRSPSPNPRDRPASPPTRRRRSQSPYRNSNRAEIDRPNVKDIDPNRRRARENALLEKQINMALADDGDADGTVATTKKSADEIARAEFAKLLGSRSGGAYIPPAKLRAMQAEAAKDKTSAEYQRISWDALKKSINGLINKVNISNIKHIVPELFGENLIRGRGLFARSVMRAQASSLPFTPVFAALVAIINTKLPQVGELVLIRLISQFRRAYKRNDKTVCHATSTFIAHLCNQYVAHEIVALQILLLCLDRPTDDSIEVAVGFMREVGQFLSENSPKANNTVFERFRAVLHEGQISKRCQYMIEVLFQVRKDKYKDNPAVPEGLDLVEEEEQITHRVTLDDELQVQESLNLFKADPNFVQNEERYNAIKREILGDSDDESGTESGSEYSESEDDEDEDVAPEKAGIQDMTETNLINLRRTIYLTIMNSLNFEEAVHKLMKVNIPEGREIELCNMVIECCSQERTYSNFYGLIGERFCKLHRIWTDAFQEAFQKYYDTIHRYETNKLRNIGRFFGHLLASDGISWAVLHVVHMNEEETTSSSRIFVKIVLQEMVEEMGINRVAERFRIPDLKPAFAGMFPMDNPKNARFSINYFTSIGMGKVTEDMREYLQNAPKLLAAQQAALAAAESSDSDTDSSSDISSSSDSDSDTDSDASSYSRRSRRRRYSSDSRSPPPQRRRYSSDSRSPSPPPRRRQYSDEPRSPSPPPRRRRYSDDSRSPSPPPRRRYSGDSRSPSPPPRRRYADDSRSPSPPPHRRRYSDDSRSPSPPPRRRRYSDNSRSPSPPPRRR
What is the function of this protein?
Involved in pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-splicing factor CWC22.
What is the protein family that this protein belongs to?
Belongs to the CWC22 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RFC2_CHICK
Sequence: MEEEEVLEVVEDEKAGPAAAEKRGPTDTLGSAPAASGHYELPWVEKYRPLKLCEVVGNEDTVSRLEVFAKEGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAVLELNASNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDSQILARLLKIVEKEDVPYTDDGLEAIIFTAQGDMRQALNNLQSTYSGFGFINSENVFKVCDEPHPLLVKEMIQHCINANIDEAYKILAHLWRLGYSPEDVIGNIFRVCKTFQMPEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQKTAAPAAS
What is the function of this protein?
The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1.  This subunit binds ATP (By similarity).
What are the official names of this protein?
Replication factor C subunit 2, Activator 1 40 kDa subunit, A1 40 kDa subunit, Activator 1 subunit 2, Replication factor C 40 kDa subunit, RF-C 40 kDa subunit, RFC40.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FPG_HERA2
Sequence: MPELPEVETVRRSLEQELVGRYFVALRSLGWPKIVDTHSPELFAEAIAQRQIQQVQRRAKYLLIELDNHETLIVHLRMTGQMLVVAADEPADRHTHVVVALDNGRELRFHDPRKFGRWSLVDRSGVAALNQRLGPEPLGDDFTLDDFAQRLSRKATKIKPTLLDQSVLAGVGNIYADEALWLAKIHPLRSANSLNANEIAELFEAIKTVLRNSIEHRGTTLVNYRDAYGASGENQYHLEAYGRTGEPCRRCGTPIERIVVAQRSTHICPVCQA
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: TRMN6_SALTY
Sequence: MSQSGSVLRRNGFTFKQFFVAHDRCAMKVGTDGILLGAWAPVADVKRILDIGTGSGLLALMLAQRTDDNVPIDAVELDAGAAMQAQENVAHSPWPHRITVHTDDIQRWAPRQTVRFDLIISNPPYYEPGVECATPQREQARYTATLDHQTLLAIAADCITEDGFFCVVLPEQIGNAFTQQALNMGWHLRLRTDVAENEARLPHRVLLAFSPQAGECFSDRLVIRGSDQHYSESYTALTQAFYLFM
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIO2_CAEEL
Sequence: MQKALKLGSFFARSAISVKPTLATSKMTQLRHFSHGASVFDIDSVEDFTEKVIQSSVPVIVDFHAEWCGPCQALGPRLEEKVNGRQGSVLLAKINVDHAGELAMDYGISAVPTVFAFKNGEKISGFSGVLDDEQLDDFIEDVLAA
What is the function of this protein?
Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
What are the official names of this protein?
Probable thioredoxin-2.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
Protein: SPAR_SHISO
Sequence: MDISSWFESIHVFLILLNGVFFRLAPLFFFLPFLNNGIISPSIRIPVIFLVASGLITSGKVDIGSSVFEHVYFLMFKEIIVGLLLSFCLSLPFWIFHAVGSIIDNQRGATLSSSIDPANGVDTSELAKFFNLFSAVVFLYSGGMVFILESIQLSYNICPLFSQCSFRVSNILTFLTLLASQAVILASPVMIVLLLSEVLLGVLSRFAPQMNAFSVSLTIKSLLAIFIIFICSSTIYFSKVQFFLGEHKFFTNLFVR
What is the function of this protein?
Required for surface presentation of invasion plasmid antigens.  Could play a role in preserving the translocation competence of the ipa antigens.  Required for invasion and for secretion of the three ipa proteins (By similarity).
What are the official names of this protein?
Surface presentation of antigens protein SpaR, Spa29 protein.
What is the protein family that this protein belongs to?
Belongs to the FliR/MopE/SpaR family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRXH_WHEAT
Sequence: MAASAATATATAAAVGAGEVISVHSLEQWTMQIEEANAAKKLVVIDFTASWCGPCRIMAPIFADLAKKFPAAVFLKVDVDELKPIAEQFSVEAMPTFLFMKEGDVKDRVVGAIKEELTTKVGLHAAQ
What is the function of this protein?
Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide.  The H form is known to activate a number of cytosolic enzymes.
What are the official names of this protein?
Thioredoxin H-type, Trx-H, TrxTa.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. Plant H-type subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AHL24_ARATH
Sequence: MDPVQSHGSQSSLPPPFHARDFQLHLQQQQQEFFLHHHQQQRNQTDGDQQGGSGGNRQIKMDREETSDNIDNIANNSGSEGKDIDIHGGSGEGGGGSGGDHQMTRRPRGRPAGSKNKPKPPIIITRDSANALRTHVMEIGDGCDLVESVATFARRRQRGVCVMSGTGNVTNVTIRQPGSHPSPGSVVSLHGRFEILSLSGSFLPPPAPPTATGLSVYLAGGQGQVVGGSVVGPLLCAGPVVVMAASFSNAAYERLPLEEDEMQTPVHGGGGGGSLESPPMMGQQLQHQQQAMSGHQGLPPNLLGSVQLQQQHDQSYWSTGRPPY
What is the function of this protein?
Transcription factor that specifically binds AT-rich DNA sequences related to the nuclear matrix attachment regions (MARs).
What are the official names of this protein?
AT-hook motif nuclear-localized protein 24.
What are the subcellular locations of this protein?
Nucleus.
Protein: 3NB2_TRIBI
Sequence: MKTLLLALVVLAFVCLGSADQVGLGKEQIDRGRRQAIGPPFTRCSQCNRNRSPQCFIEDRCTPGDFTCYTVYKPNGNGGEDWVVKGCAKTCPTAGPGERVKCCYSPRCNKN
What is the function of this protein?
Potent postsynaptic neurotoxin.  Displays readily reversible competitive antagonism at the nicotinic acetylcholine receptor (nAChR).
What are the official names of this protein?
Toxin 3FTx-Tri2.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Ancestral subfamily. Boigatoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RCC1_HUMAN
Sequence: MSPKRIAKRRSPPADAIPKSKKVKVSHRSHSTEPGLVLTLGQGDVGQLGLGENVMERKKPALVSIPEDVVQAEAGGMHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEKVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGSRGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPAVSSVACGASVGYAVTKDGRVFAWGMGTNYQLGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLLVKDKEQS
What is the function of this protein?
Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP, and thereby plays an important role in RAN-mediated functions in nuclear import and mitosis (PubMed:1944575, PubMed:17435751, PubMed:20668449, PubMed:22215983, PubMed:11336674).  Contributes to the generation of high levels of chromosome-associated, GTP-bound RAN, which is important for mitotic spindle assembly and normal progress through mitosis (PubMed:12194828, PubMed:17435751, PubMed:22215983).  Via its role in maintaining high levels of GTP-bound RAN in the nucleus, contributes to the release of cargo proteins from importins after nuclear import (PubMed:22215983).  Involved in the regulation of onset of chromosome condensation in the S phase (PubMed:3678831).  Binds both to the nucleosomes and double-stranded DNA (PubMed:17435751, PubMed:18762580).
What are the official names of this protein?
Regulator of chromosome condensation, Cell cycle regulatory protein, Chromosome condensation protein 1.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Cytoplasm. Note=Predominantly nuclear in interphase cells (PubMed:12194828). Binds to mitotic chromosomes (PubMed:12194828, PubMed:17435751, PubMed:20668449).
Protein: PELI1_MOUSE
Sequence: MFSPDQENHPSKAPVKYGELIVLGYNGSLPNGDRGRRKSRFALFKRPKANGVKPSTVHIACTPQAAKAISNKDQHSISYTLSRAQTVVVEYTHDSNTDMFQIGRSTESPIDFVVTDTVPGSQSNSDTQSVQSTISRFACRIICERSPPFTARIYAAGFDSSKNIFLGEKAAKWKTSDGQMDGLTTNGVLVMHPRNGFTEDSKPGIWREISVCGNVFSLRETRSAQQRGKMVEIETNQLQDGSLIDLCGATLLWRTAEGLSHTPTVKHLEALRQEINAARPQCPVGFNTLAFPSMKRKDVVDEKQPWVYLNCGHVHGYHNWGNKEERDGKDRECPMCRSVGPYVPLWLGCEAGFYVDAGPPTHAFSPCGHVCSEKTTAYWSQIPLPHGTHTFHAACPFCAHQLAGEQGYIRLIFQGPLD
What is the function of this protein?
E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins (By similarity).  Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6.  Mediates 'Lys-63'-linked polyubiquitination of IRAK1 allowing subsequent NF-kappa-B activation (PubMed:16951688).  Mediates 'Lys-48'-linked polyubiquitination of RIPK3 leading to its subsequent proteasome-dependent degradation; preferentially recognizes and mediates the degradation of the 'Thr-182' phosphorylated form of RIPK3 (PubMed:29883609).  Negatively regulates necroptosis by reducing RIPK3 expression (PubMed:29883609).  Mediates 'Lys-63'-linked ubiquitination of RIPK1 (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase pellino homolog 1, Pellino-1, RING-type E3 ubiquitin transferase pellino homolog 1.
What is the protein family that this protein belongs to?
Belongs to the pellino family.
Protein: FBX15_MACFA
Sequence: MPSEILLKIFSYLDAVSLLCAGCVSRRFYHLANDNFIWIRIYSTAFSPTRSNWKVNSVEKIAVSVSFLSVQDKEAGYWKKEYITKQIASVKAALADILKPVNPYTGLPVKTKEALRMFGLGWAIILKEKSGKEYIMEHVDLSVNDTSVTVIWYGKNWPCLASLSTLDLCGVTPVFMDWYKTPTKHRLRWHSLIAKYNLSHLTVSTMIGCDRLIRIFCLHPGLLVGVWKKEEELAFVMANLHFHHLVERSTLGSATIPYELPPHSPFLDDSPEYGLHGYQLHVDLHSGGVFYLCGTFRNLFTKKGNIENGHVKLIVIHLKNNREHLPLIGKVGLSWKTDILDGCIKSCSMMDVTLLDEHGKPFWCFSSPVCMRSPATPADGPSFLGQTYSVDYVDAEGRVHVELVWIRETEEYLIVNLVLYLSIAKINRWFGTEY
What is the function of this protein?
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
What are the official names of this protein?
F-box only protein 15.
Protein: RPOB_MYCTO
Sequence: MLEGCILADSRQSKTAASPSPSRPQSSSNNSVPGAPNRVSFAKLREPLEVPGLLDVQTDSFEWLIGSPRWRESAAERGDVNPVGGLEEVLYELSPIEDFSGSMSLSFSDPRFDDVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTFIINGTERVVVSQLVRSPGVYFDETIDKSTDKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSEQIVERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHVGEPITSSTLTEEDVVATIEYLVRLHEGQTTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTTQDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPIETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIVYLTADEEDRHVVAQANSPIDADGRFVEPRVLVRRKAGEVEYVPSSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVAEESGVIEEVSADYITVMHDNGTRRTYRMRKFARSNHGTCANQCPIVDAGDRVEAGQVIADGPCTDDGEMALGKNLLVAIMPWEGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNISDEVLADLDERGIVRIGAEVRDGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDEDELPAGVNELVRVYVAQKRKISDGDKLAGRHGNKGVIGKILPVEDMPFLADGTPVDIILNTHGVPRRMNIGQILETHLGWCAHSGWKVDAAKGVPDWAARLPDELLEAQPNAIVSTPVFDGAQEAELQGLLSCTLPNRDGDVLVDADGKAMLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLKELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASVEDLA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: EST2C_RAT
Sequence: MARKQPHSWLNAVLFGLLLILIHVWGQDSPESSSIRTTHTGQVRGKLDHVRDTKAGVHTFLGIPFAKAPVGPLRFAPPEDPEPWSGVRDGTSHPAMCLQNIDMLDEVGLTDMKMILSSIPMSEDCLYLNIYTPAHAHEGSNLPVMVCIHGGALVIGMASMCDGSLLAVNEDLVVVAIQYRLGVLGFFSTGDEHARGNWGYLDQVAALRWVQQNIAHFGGNPNRVTIFGVSAGGTSVSSHVISPMSQGLFHGAIMESGVALLPDLISETSETVSTTVAKLSGCEATDSETLVRCLRAKSGAEILVINKVFKMIPAVVDGEFLPRHPKELLASEDFHPVPSIIGVNTDEYCCTIPMVMGTAQIIKELSRENLQAVLKDTAAQMMLPPECGDLLMEEYMGNTDDPQTLQIQYAEMMGDFLFVIPALQVAHFQRSHAPVYFYEFQHAPSYFKNVRPPHVKADHADEVPFVFGSFFWGIKVDFTEEEKLLSRRMMKYWANFARHGNPNSEGLPYWPVLDHDEQYLQLDTQPAVDRALKARRLQFWTKTLPQKIQELNGAQKNHAEL
What is the function of this protein?
Hydrolase with high activity towards palmitoylcarnitine.  Is also active with p-nitrophenylacetate and alpha-naphthylacetate (By similarity).  May also hydrolyze retinyl esters (PubMed:12230550).
What are the official names of this protein?
Acylcarnitine hydrolase, ACH M1, Carboxylic ester hydrolase.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
Microsome. Endoplasmic reticulum.
Protein: RL19_BURCH
Sequence: MNLIAKLEQEEIERALAGKTIPDFAPGDTVIVNVNVVEGNRKRVQAYEGVVIAIRNRGLNSNFIVRKISSGEGVERTFQTYSPLLASIVVKRRGDVRRAKLYYLRERSGKSARIKEKLVSKDRAAAASQE
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: TGIF2_MOUSE
Sequence: MSDSDLGEDEGLLSLTGKRKRRGNLPKESVKILRDWLYLHRYNAYPSEQEKLSLSGQTNLSVLQICNWFINARRRLLPDMLRKDGKDPNQFTISRRGGKASDVALPRGSSPSLLAVSVPAPTNMLSLSVCSMPLHSGQGEKPAAPFPQVELESPKALVTPASTLTLLTRAEAGSPTGGLFNTPPPTPPEQDKDDFSSFQLLVEVALQRAAEMELQKQQEPAPPLLHTPLPFVSENAK
What is the function of this protein?
Transcriptional repressor, which probably repress transcription by binding directly the 5'-CTGTCAA-3' DNA sequence or by interacting with TGF-beta activated SMAD proteins.  Probably represses transcription via the recruitment of histone deacetylase proteins (By similarity).
What are the official names of this protein?
Homeobox protein TGIF2, 5'-TG-3'-interacting factor 2, TGF-beta-induced transcription factor 2, TGFB-induced factor 2.
What is the protein family that this protein belongs to?
Belongs to the TALE/TGIF homeobox family.
What are the subcellular locations of this protein?
Nucleus. Note=Excluded from nucleoli.
Protein: PBX1_MOUSE
Sequence: MDEQPRLMHSHAGVGMAGHPGLSQHLQDGAGGTEGEGGRKQDIGDILQQIMTITDQSLDEAQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDNMLLAEGVAGPEKGGGSAAAAAAAAASGGAGSDNSVEHSDYRAKLSQIRQIYHTELEKYEQACNEFTTHVMNLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQEEANIYAAKTAVTATNVSAHGSQANSPSTPNSAGSSSSFNMSNSGDLFMSVQSLNGDSYQGAQVGANVQSQVDTLRHVISQTGGYSDGLAASQMYSPQGISANGGWQDATTPSSVTSPTEGPGSVHSDTSN
What is the function of this protein?
(Microbial infection) In complex with PREP1, binds to the 5'-TGATTGAC-3' consensus sequence in the U5 region of Moloney murine leukemia virus and promotes viral transcription.
What are the official names of this protein?
Pre-B-cell leukemia transcription factor 1, Homeobox protein PBX1.
What is the protein family that this protein belongs to?
Belongs to the TALE/PBX homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CSTA_BACSU
Sequence: MNAVTIVIASMCILAIAYRLYGTFMMVKVLKVNDDKPTPAHALEDGKDYVPTNKWVSFGHHFAAIAAAGPLVGPILAAQFGYLPGLLWLLIGAVIGGAVHDIVVLFASMRKNGKSLSEVAKDELGPVAGFCTGLSMLFIITITMAGLSMVVLHALERNPWGTFAVGITIPIAMGVGLFYKKTGNLKLASTVGFLFLMAGVFIGPWVQTTALGDFLTLDTKTLAIALPVYAFFAAALPVWLLLAPRDYLSSFMKIGVFIALIVGVFVVNPSIPFPAFTEFVKGGGPVLAGPVWPFISITIACGAISGFHAFVGSGTTPKMLNKWSDMKPVAFGAMLVECLVGIMALIAATALQPADYFAINSTPEVFRTLGMNVVHLPELSGEIGLDLEGRTGGAVTLAVGMTYIFTGMPFFSHLASYFFQFVIMFEAVFILTAIDAGTRVARYLIQDFFGEVYKPLKKTDWIPGSVFASALACLMWGYLLYSGDIGSIWALFGVSNQLMASVGLIIGATIVLKIADKRRYILTCLIPLAYLYVTVNYAGYWMVRNVYLNPEAAGYSVLNGVLSIIMLVLGFIIIVAAVKKWAQMWKDPSLRMEASIPG
What is the function of this protein?
Involved in peptide utilization.
What are the official names of this protein?
Peptide transporter CstA, Carbon starvation protein A homolog.
What is the protein family that this protein belongs to?
Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NUSB_LEGPA
Sequence: MEKQSIRGKRRARKFALQALYQWLMSGTDLHEIEAQFRTINNMDKVDGEYFCRLLYGIPTHVEALEASLLPYLDREINALNPIELTVLRIGSFELFHCPEIPYKVILDESVSLTKEFGSQEGYRYVNGVLNNLAKQVRSVEVSLDNE
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: CGH1_CAEEL
Sequence: MSGAEQQQIVPANNGDENWKAGLNLPAKDRRFKTADVTDTKGVEFEDFCLGRDLLMGIFEKGWEKPSPIQEASIGVALTGQDILARAKNGTGKTGAYCIPVIEKIQPALKAIQAMVIVPTRELALQTSQICVELSKHIQLKVMVTTGGTDLRDDIMRLNGTVHLVIATPGRILDLMEKGVAKMEHCKTLVLDEADKLLSQDFQGILDRLINFLPKERQVMLYSATFPNTVTSFMQKHMHKPYEINLMEELTLLGVTQYYAFVQEKQKVHCLNTLFRKLQINQSIIFCNSTQRVELLAKKITEIGYSCYYIHSKMAQNHRNRVFHDFRQGNCRNLVCSDLLTRGIDIQAVNVVINFDFPRNAETYLHRIGRSGRFGHLGVAINLITYEDRHTLRRIEQELRTRIEPIPKTVDPKLYVADQQLVDAADETTA
What is the function of this protein?
Probable RNA helicase required for oocyte and sperm function.  Also required to prevent the physiological germline apoptosis mechanism killing essentially all developing oocytes.
What are the official names of this protein?
ATP-dependent RNA helicase cgh-1, Conserved germline helicase 1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Cytoplasmic when associated with pgl-1. Associates with P granules and this localization is dependent on ifet-1.
Protein: UBIE_SERP5
Sequence: MADQPQETTDFGFRTVARDEKQAMVADVFHSVAAKYDVMNDLMSFGIHRIWKRFTIDCSGVRRGQRVLDLAGGTGDLAAKFSRMVGEQGQVVLADINDSMLKMGREKLRDRGIIGNVNYVQANAEALPFPDNYFDCITISFGLRNVTDKDKALRSMFRVLKPGGRLLVLEFSKPLLAPLSKAYDAYSFHVLPKIGELVVKDPESYRYLAESIRMHPDQETLKGMMGAAGFDNVTYFNLTGGIVALHRGFKF
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: TET50_UNKP
Sequence: MTKHIKILVIGVGVAGPAVAYWLKRFGFSPVLIEKSAAVRKGGQALDIRGIATHIAKEMGIYDQICNMRTQIKCGRYVDVKGNVLHEEQGETFGFRQDDEVEILRGDLVEILMKAIADIPCEFKQSVIKIEQNEDSVTVTYKDGRVENYDLVIAADGIHSATRGMVFSKNEYQLINLGSYVSAFTIPNYLGLDHMELLCESNHKLVTLQSDSQADKAMAGFMFRSKHVLEDIRDEQEQKHFLHASFQNFGWETQNILNRMPESDDFYFDAITQIKMKSWTKGRIALIGDAAYCPSPLSGQGNNLAFVGAYILAGELKKADGDYIQAFTRYNELLHPFVEANQQFGVWVSESFLLKDDEVSKEIAEARSNKILAMIKSVSNSINLPQYE
What is the function of this protein?
An FAD-requiring monooxygenase active on tetracycline antibiotic and some of its derivatives, which leads to their inactivation (PubMed:26097034).  Expression in E. coli confers high resistance to tetracycline and oxytetracycline, does not confer resistance to minocycline or tigecycline.  Degrades tetracycline and oxytetracycline; the reaction requires NADPH (PubMed:26097034).  Degrades and confers resistance to chlortetracycline (PubMed:28481346).
What are the official names of this protein?
Flavin-dependent monooxygenase, Tetracycline destructase Tet(50), Tet(50).
What is the protein family that this protein belongs to?
Belongs to the aromatic-ring hydroxylase family.
Protein: FCTA_SHIDS
Sequence: MSTPLQGIKVLDFTGVQSGPSCTQMLAWFGADVIKIERPGVGDVTRHQLRDIPDIDALYFTMLNSNKRSIELNTKTAEGKEVMEKLIREADILVENFHPGAIDHMGFTWEHIQEINPRLIFGSIKGFDECSPYVNVKAYENVAQAAGGAASTTGFWDGPPLVSAAALGDSNTGMHLLIGLLAALLHREKTGRGQRVTMSMQDAVLNLCRVKLRDQQRLDKLGYLEEYPQYPNGTFGDAVPRGGNAGGGGQPGWILKCKGWETDPNAYIYFTIQEQNWENTCKAIGKPDWITDPAYSTAHARQPHIFDIFAEIEKYTVTIDKHEAVAYLTQFDIPCAPVLSMKEISLDPSLRQSGSVVEVEQPLRGKYLTVGCPMKFSAFTPDIKAAPLLGEHTAAVLQELGYSDDEIAAMKQNHAI
What is the function of this protein?
Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR).  Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate (By similarity).
What are the official names of this protein?
Formyl-CoA:oxalate CoA-transferase, FCOCT, Formyl-coenzyme A transferase, Formyl-CoA transferase.
What is the protein family that this protein belongs to?
Belongs to the CoA-transferase III family. Frc subfamily.