PharMolix/UniProtQA huggingface dataset:
Protein: GAL1_SERP5
Sequence: MSLKNLTHALFTERFGYAPTLTIQAPGRVNLIGEHTDYNDGFVLPCAIDYQTVIACAKRDDRQIRVIAADYEGQQDQFSLDSPIVSHPDQRWSDYVRGVIKHLQQRNADFGGADLVISGNVPQGAGLSSSASLEVAVGQAMQALYALPLDGVALALNGQEAENQFVGCNCGIMDQLISALGEKDHALLIDCRTLETRAVSVPEDIAVVIINSNVKRGLVDSEYNTRREQCEEAARFFGVKALRDVSPDLFFPIQHELDPIVAKRARHVISENDRTLAAADALAAGDMKLMGKLMAESHVSMRDDFEITVPPIDRLVEIVKSVIGDRGGVRMTGGGFGGCIVALMPLALVEPVRAAVAREYPLQTNGLKETFYVCKASEGAGTC
What is the function of this protein?
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFEMO_STAAC
Sequence: MKKLTTLLLASTLLIAACGNDDSKKDDSKTSKKDDGVKAELKQATKAYDKYTDEQLNEFLKGTEKFVKAIENNDMAQAKALYPKVRMYYERSEPVAEAFGDLDPKIDARLADMKEEKKEKEWSGYHKIEKALYEDKKIDDVTKKDAQQLLKDAKELHAKADTLDITPKLMLQGSVDLLNEVATSKITGEEEIYSHTDLYDFKANVEGAQKIYDLFKPILEKKDKKLSDDIQMNFDKVNQLLDKYKDNNGGYESFEKVSKKDRKAFADAVNALGEPLSKMAVITE
What are the official names of this protein?
Efem/EfeO family lipoprotein.
What is the protein family that this protein belongs to?
Belongs to the EfeM/EfeO family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: ALK2_YEAST
Sequence: MNFDAVADQQMTDRRYFALEVAESDDADSSLNSSSMGSPAVDVGRKVYKITSHKGSAEDESQSFFTSSDSPTSKTRPVGKTIENDDYYGKRSSTGSSLKQLFNKININDTAHSSNKENVSQSVLSENKLLSPSKRLSKQGLTKVTNSKFRTPLRPISNQSTLSRDEPVKDFRSLKFRSGSDFKCWGDEKTSSHVHSSSVNSVNSFTSTTSSSKWKFWKNDNLLSRSLSSRSVNDQDPNFVQPKPTNSLQKKSSISSFHNSIFGGGKHTEKKRNSGFIMPDHQSTKELNHKHSSSNLSFRSLKHKTSHSSLNKLKVRRKGNTQELNHPIKKTCQISLPVPDQVSKDKIQLKLKNSTSLASLSSEVTPINTLDYNDSILQQILQLCDVKYILHDLREAQSLGLFTLNTRSVQLSHNFWQTYHSDMQTSLICKKVCLGALSDLTTSNLISLHELKSLRLIQGTSGVANLLQAYVVPSNQCENDQNLILYLFFKYQGTPLSRCSNIDYSQALSIFWQCSSILYVAESKFQLEHRNLTLDHILIDSKGNVTLIDMKCCRFLNIDNNKASYTRLDHHYFFQGRGTLQFEIYELMRSMLPQPISWATFEPRTNLLWLYHLSSSLLKMAKKAVVSGALNREENILIELTHLLDPARKHSKTIFKKELVIRTCGDLLSLKGEIMQ
What is the function of this protein?
Serine/threonine haspin-like protein kinase involved in cell cycle regulation.
What are the official names of this protein?
Serine/threonine-protein kinase Haspin homolog ALK2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Haspin subfamily.
Protein: SYL_MYCS2
Sequence: MTEPATTPTTPDEQIPRHRYNADLAGQIERAWQETWSDRGTFNVANPVGSLAPTDGSDVPADKMFVQDMFPYPSGDGLHVGHPLGYIATDVYARYYRMLGRNVLHALGFDAFGLPAEQYAVQTGTHPRTRTEANIVNFRRQLGRLGLGHDTRRSFSTTDVDYYKWTQWIFLQIYNAWFDRDQNKARRISELVEEFESGKRTLDDGRNWADLSKGERADVIDGYRLVYRADSMVNWCPGLGTVLANEEVTSEGRSDRGNFPVFRKRLRQWMMRITAYSDRLLEDLDVLDWPEKVKTMQRNWIGRSTGASVLFATAADDIEVFTTRPDTLFGATYLVLAPEHDLVDTLVTDAWPDGTDERWTYGAATPREAVAAYRTDIAAKSDLERQENKTKTGVFLGAYATNPADGKQVPIFIADYVLAGYGTGAIMAVPGGDQRDWDFAKEFGLPIIEVVTGGDISEAAYAGDGTMVNSGFLDGMDVASAKEAIIARLEADGRGKRRVEYKLRDWLFARQRYWGEPFPIVYDADGRAHPLPESALPVELPDVPDYSPVLFDPDDADSEPSPPLNKATEWVHVELDLGDGLQSYTRDTNVMPQWAGSSWYELRYTDPHNPDEMCAKENEAYWMGPRPDEHGPEDPGGVDLYVGGVEHAVLHLLYSRFWHKVLYDLGYVSSREPYRRLVNQGYIQAFAYTDSRGTYVPAAEVIERDGKFFWPGPDGEIEVNQEFGKIGKSLKNSVSPDEICDNYGADTLRVYEMSMGPLEASRPWATKDVVGAHRFLQRVWRVVIDETSGNVRVVEHEALSDETLRLLHRTIEGVREDYAALRNNTAAAKLIEYTNHLTKEGVAARAAIEPLVLMVAPLAPHLAEELWKRLGHDTSLAHGPFPEADPQYLVEDTIEFPVQVNGKVRGKIVVAADADKAALEAAALADEKVQAFLAGATPKKVIVVPGRLVNLVV
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSRP_STRM5
Sequence: MSTIRPVFYVSDGTGITAETIGHSLLTQFSGFSFITDRMSFVDDPEKAREACSRIQAAGERYQVRPIVVNSCVDQSLSLILAESGALMLDVFAPFIEPLERELSSSRVNRVGQAHGMVDFDTYHRRINAMNFALTHDDGIAVNYDDADVILVAVSRAGKTPTCIYLALHYGVRAANYPLTDEDLESDRLPPRLRNYRRKLFGLTIDPDRLQQIRQERRPNSRYANLDTCKREVAAAEVMFQMERIPTLSTTHTSIEEISSKVLATLGLQRELY
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: ACHA7_CHICK
Sequence: MGLRALMLWLLAAAGLVRESLQGEFQRKLYKELLKNYNPLERPVANDSQPLTVYFTLSLMQIMDVDEKNQVLTTNIWLQMYWTDHYLQWNVSEYPGVKNVRFPDGLIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQKCNLKFGSWTYGGWSLDLQMQEADISGYISNGEWDLVGIPGKRTESFYECCKEPYPDITFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWTRVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLSSMEMNTVSGQQCSNGNMLYIGFRGLDGVHCTPTTDSGVICGRMTCSPTEEENLLHSGHPSEGDPDLAKILEEVRYIANRFRDQDEEEAICNEWKFAASVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA
What is the function of this protein?
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
What are the official names of this protein?
Neuronal acetylcholine receptor subunit alpha-7.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-7/CHRNA7 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: TRX1_PSHV1
Sequence: MANMKPNLTDLFRLRERADEGAARRENDRLLGLGSTVPQLLRPVWSGAPTVTGNIIGAIVNRGSAGTELLRTGPATNSGGGRMAAQQHAFGADDAAGVKAALLGSIAPTADALRAQQVLTTQVTVTDMCKPDVEGPGSLMLFFRGVRRLLIKLSAETMVRNDLINELETAFMILNRICGLPPVGTNGINNFEASLVSLNVLAAAAAPHYRNTCEVDALRTFVLAGGKDSKLNEKLTNLDLILQASVESRNFPHSILFPAGALTESVNSTNVACVKMLMNGSVELEGGLTRPCGSFRFPACLFLDLDDTRQCGVVPRGADRADGLFYVYLLFLYSTETWHPSYEIYVAKSALGEAGLQSMLDEKFARRRVNNTVAAAPPAGNFYARGRQREDGDWRCYIEDAYRRASGNNAVNPLEQGARPTDLHISFAGVPDRNSATYAAFCQLGVSLGPWSSACRYTTVQRHGLGLKYVELPGLSLKIGTWRACY
What is the function of this protein?
Structural component of the T=16 icosahedral capsid.  The capsid is composed of pentamers and hexamers of major capsid protein/MCP, which are linked together by heterotrimers called triplexes.  These triplexes are formed by a single molecule of triplex protein 1/TRX1 and two copies of triplex protein 2/TRX2.  Additionally, TRX1 is required for efficient transport of TRX2 to the nucleus, which is the site of capsid assembly.
What are the official names of this protein?
Triplex capsid protein 1.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae TRX1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: BSC5_ALTBR
Sequence: MLEGTLQDCWTSISKMQLHWTVLGLLPVLFIAILGPRVRQIWVNYVHLTKIPSPHKKDYFCFVTETTRAEFLNECARLLRKGFASGDVIRLHASWDHIVVLSPSYAECLRADEKFSPDTFSDKEMFGAVPGFEPYRFLCTHRDLVRNVISMRLNRCFVPATRYLSEAIDDALRKQMGNDSEWREVPLGNAVLKILTQSSFRALQGPELCYDDEWLDIATQYIVTSVTGVTALRKLPKFLVPLIHWFHPDAIKSRRLLSRARAKLIPFYEKRKKELYQARRNGTYRPEDADAFGWYEELADGRDYDPVVAQLTVAVAATHSTTDFMCQFLSDMVRYPEYIQPLRDELILALKEKGWKASTILQLPLLDSVMKESQRLKPVAMGFMRSIAQHDVYLQDAVKIPKNASVIVSAHSMRDATVYENPDSFDGYRFINPTKHPESRHFTSVSVNHMGFGFGKHACPGRFFVNLETKILIAHLLLKYDWKFANDGCPAIRTSGFDQVVDPSAKMLVRRRKEEIRIEALYE
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of the diterpene glucoside brassicicene C (PubMed:19097780).  In the first step of the brassicicene C biosynthesis, the bifunctionnal diterpene synthase bsc8 that possesses both prenyl transferase and terpene cyclase activity, converts isopentenyl diphosphate and dimethylallyl diphosphate into geranylgeranyl diphosphate (GGDP) that is further converted into fusicocca-2,10(14)-diene, the first precursor for brassicicene C (PubMed:19097780).  Fusicocca-2,10(14)-diene is then substrate of cytochrome P450 monooxygenase bsc1 for hydroxylation at the C-8 position (PubMed:19700326).  Oxidation at C-16 position to aldehyde is then catalyzed by the cytochrome P450 monooyxygenase bsc7, yielding fusicocca-2,10(14)-diene-8-beta,16-diol (PubMed:19700326).  Follows the isomerization of the double bond and reduction of aldehyde to alcohol catalyzed by the short-chain dehydrogenase/reductase bsc3 to yield the diol compound fusicocca-1,10(14)-diene-8 beta,16-diol (Probable).  The next step is the oxidation at the C-3 position of fusicocca-2,10(14)-diene-8-beta,16-diol catalyzed by the alpha-ketoglutarate dependent dioxygenase bsc9, to produce a triol compound (PubMed:21299202).  Methylation of the hydroxy group at position 16 is performed by the methyltransferase bsc6 (PubMed:19097780).  16-O-methylation is followed by oxidation at the C-13 position to ketone and an alkyl shift of the methyl group leads to brassicicene C (Probable).  Although the probable acetyltransferase bsc4 is included in the gene cluster, no acetylation reactions are necessary for brassicicene C biosynthesis.  However, the fact that brassicicene E, which is a structurally related compound having an acetoxy group at position 12, was previously isolated from another strain of A. brassicicola suggests that the ATCC 96836 strain might also produce a small amount of brassicicene E (Probable).
What are the official names of this protein?
Cytochrome P450 monooxygenase bsc5, Brassicicene C biosynthetic gene cluster protein 5.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RNAS1_MIOTA
Sequence: MALDKSVILLPLLVLVLLVLGCLGRESRAKKFQRQHMDSGSSPSSNSTYCNQMMKRRSMTQGRCKPVNTFVHEPLVDVQNVCFQEKVTCKNGQTNCFKSKSSMHITDCRLTNGSRYPNCAYRTSPKERRIIVACEGSPYVPVHFDASVEDST
What is the function of this protein?
Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides.  Acts on single-stranded and double-stranded RNA (By similarity).
What are the official names of this protein?
Ribonuclease pancreatic, RNase 1, RNase A.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: FRG2_HUMAN
Sequence: MGKGNEDSDLHCSSIQCSTDQPPFQQISFTEKGSDEKKPFKEKGKTAFSHSSEKHIQRQGSEPNPNKENSEETKLKAGNSTAGSEPESSSYRENCRKRKMSSKDSCQDTAGNCPEKECSLSLNKKSRSSTAVHNSEIQETCDAHHRGHSRACTGHSKRHRSRALGVQTPSIRKSLVTSVRAMSEAVYQDLAQVWAQQIHSPLTCEQLTLLTRLRGPLCAQVQTLYSMATQAAYVFPAESWLVPATLPGPGESALDREAHPFPGQEITETVSGSDEAKL
What are the official names of this protein?
Protein FRG2, FSHD region gene 2 protein.
What is the protein family that this protein belongs to?
Belongs to the FRG2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: VINT_BPL2
Sequence: MNIEKALMNYYELTLASYEDSTNRYHYRIVQHLIKGLKYIKVKKLEKVDITIGYKLIDYLKNHTHNGNNSIKKIINYLRKVMQHYRITTSIIDLPHLPNDTKPFERFYHDDLELIMTYTKNLNSSKNSITYKSFIRLLLDSGLRVSEALNIKISDMDFKNKVIRVLSSKTRKQRYAPFSSFSLKYIKELIEVNPKRDYLFYNFIKDRQTNKNDIKLFYKRLKKHLNLERIHTHRFRKTFASILIENGLNIDDLQKIFDHSRIETTIKYVQHNEKRALQEYKKYNDWGLN
What is the function of this protein?
May function as an integrase.
What are the official names of this protein?
Probable integrase/recombinase, ORF5.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family.
Protein: SMU1_ARATH
Sequence: MALEIEARDVIKIMLQFCKENSLNQTFQTLQSECQVSLNTVDSVETFISDINSGRWDSVLPQVSQLKLPRNKLEDLYEQIVLEMIELRELDTARAILRQTQVMGVMKQEQAERYLRMEHLLVRSYFDPHEAYGDSTKERKRAQIAQAVAAEVTVVPPSRLMALIGQALKWQQHQGLLPPGTQFDLFRGTAAMKQDVEDTHPNVLTHTIKFGKKSHAECARFSPDGQFLASSSVDGFIEVWDYISGKLKKDLQYQADESFMMHDDPVLCIDFSRDSEMLASGSQDGKIKIWRIRTGVCIRRFDAHSQGVTSLSFSRDGSQLLSTSFDQTARIHGLKSGKLLKEFRGHTSYVNHAIFTSDGSRIITASSDCTVKVWDSKTTDCLQTFKPPPPLRGTDASVNSIHLFPKNTEHIVVCNKTSSIYIMTLQGQVVKSFSSGNREGGDFVAACVSTKGDWIYCIGEDKKLYCFNYQSGGLEHFMMVHEKDVIGITHHPHRNLLATYSEDCTMKLWKP
What is the function of this protein?
Auxiliary spliceosomal protein involved in splicing of specific pre-mRNAs that affect multiple aspects of development.  Required for proper accumulation of SMU2.
What are the official names of this protein?
Suppressor of mec-8 and unc-52 protein homolog 1, AtSMU-1, RNA splicing protein SMU1, WD40 repeat-containing protein SMU1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat SMU1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MAST2_MOUSE
Sequence: MVTGLSPLLFRKLSNPDIFAPTGKVKLQRQLSQDDCKLRRGSLASSLSGKQLLPLSSSVHSSVGQVTWQSTGEASNLVRMRNQSLGQSAPSLTAGLKELSLPRRGSFCRTSNRKSLIVTSSTSPTLPRPHSPLHGHTGNSPLDSPRNFSPNAPAHFSFVPARRTDGRRWSLASLPSSGYGTNTPSSTVSSSCSSQEKLHQLPFQPTADELHFLTKHFSTENVPDEEGRRSPRMRPRSRSLSPGRSPVSFDSEIIMMNHVYKERFPKATAQMEERPSLTFISSNTPDSVLPLADGALSFIHHQVIEMARDCLDKSRSGLITSHYFYELQENLEKLLQDAHERSESSDVAFVIQLVKKLMIIIARPARLLECLEFDPEEFYHLLEAAEGHAKEGHGIKCDIPRYIVSQLGLTRDPLEEMAQLSSYDSPDTPETDDSVEGRGVSQPSQKTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVSMFCSFETKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKIGLMSLTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEIVWPEGDDALPPDAQDLTSKLLHQNPLERLGTSSAYEVKQHPFFMGLDWTGLLRQKAEFIPQLESEDDTSYFDTRSERYHHVDSEDEEEVSEDGCLEIRQFSSCSPRFSKVYSSMERLSLLEERRTPPPTKRSLSEEKEDHSDGLAGLKGRDRSWVIGSPEILRKRLSVSESSHTESDSSPPMTVRHRCSGLPDGPHCPEETSSTPRKQQQEGIWVLIPPSGEGSSRPVPERPLERQLKLDEEPPGQSSRCCPALETRGRGTPQLAEEATAKAISDLAVRRARHRLLSGDSIEKRTTRPVNKVIKSASATALSLLIPSEHHACSPLASPMSPHSQSSNPSSRDSSPSRDFLPALGSLRPPIIIHRAGKKYGFTLRAIRVYMGDTDVYTVHHMVWHVEDGGPASEAGLRQGDLITHVNGEPVHGLVHTEVVELVLKSGNKVSISTTPLENTSIKVGPARKGSYKAKMARRSKRSKGKDGQESRKRSSLFRKITKQASLLHTSRSLSSLNRSLSSGESGPGSPTHSHSLSPRSPPQGYRVAPDAVHSVGGNSSQSSSPSSSVPSSPAGSGHTRPSSLHGLAPKLQRQYRSPRRKSAGSIPLSPLAHTPSPPATAASPQRSPSPLSGHGSQSFPTKLHLSPPLGRQLSRPKSAEPPRSPLLKRVQSAEKLAAALAAAEKKLAPSRKHSLDLPHGELKKELTPREASPLEVVGTRSVLSGKGPLPGKGVLQPAPSRALGTLRQDRAERRESLQKQEAIREVDSSEDDTDEEPENSQATQEPRLSPHPEASHNLLPKGSGEGTEEDTFLHRDLKKQGPVLSGLVTGATLGSPRVDVPGLSPRKVSRPQAFEEATNPLQVPSLSRSGPTSPTPSEGCWKAQHLHTQALTALCPSFSELTPTGCSAATSTSGKPGTWSWKFLIEGPDRASTNKTITRKGEPANSQDTNTTVPNLLKNLSPEEEKPQPPSVPGLTHPLLEVPSQNWPWESECEQMEKEEPSLSITEVPDSSGDRRQDIPCRAHPLSPETRPSLLWKSQELGGQQDHQDLALTSDELLKQT
What is the function of this protein?
Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins.  Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins.  Functions in a multi-protein complex in spermatid maturation.  Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6, resulting in the inhibition of TRAF6 NF-kappa-B activation.
What are the official names of this protein?
Microtubule-associated serine/threonine-protein kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell junction. Note=Colocalizes with beta 2-syntrophin and utrophin at neuromuscular junctions.
Protein: URK_YERPP
Sequence: MTDKAHQCVIIGIAGASASGKSLIASTLYRELREQVGDQHIGVIPEDGYYKDQSHLSMEERVKTNYDHPSAMDHNLLLEHLQALKAGKPVELPLYSYTEHTRKKETVHLEPKKVIILEGILLLTDIRLRQEMNFSIFVDTPLDICLMRRMKRDVNERGRSMDSVMAQYQKTVRPMFLQFIEPSKQYADIIVPRGGKNRIAIDILKAKISQFFE
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRO1B_ACACA
Sequence: MSWQTYVDTNLVGTGAVTQAAILGLDGNTWATSAGFAVTPAQGTTLAGAFNNADAIRAGGFDLAGVHYVTLRADDRSIYGKKGAAGVITVKTSKAILVGVYNEKIQPGTAANVVEKLADYLIGQGF
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG.
What are the official names of this protein?
Profilin-1B, Acidic profilin IB, Profilin IB.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RS18_KOCRD
Sequence: MAKAEIRKPKPKQNPLKAADVTEIDYKDVALLRKFISDRGKIRARRVTGVSVQEQRKIAQAIKNAREVALLPYSGAGR
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: EFG_VIBVU
Sequence: MARKTPIERYRNIGICAHVDAGKTTTTERILFYTGLSHKIGEVHDGAATMDWMEQEQERGITITSAATTTFWRGMEAQFQDHRVNIIDTPGHVDFTIEVERSLRVLDGAVVVFCGSSGVEPQSETVWRQADKYHVPRMVFVNKMDRAGADFLRVVDQIKNRLGANPVPIQLNVGAEEDFKGVIDLIKMKMINWNEADQGMTFTYEEIPADMIELAEEWRNNLVEAAAEASEELMDKYLEEGELTEAEIKQALRARTLNNEIVLATCGSAFKNKGVQAVLDAVIEYLPSPIDVPAIKGIDENDNEVERHADDNEPFSALAFKIATDPFVGTLTFIRVYSGVVNTGDAVYNSVKQKKERFGRIVQMHANKREEIKEVRAGDIAAAIGLKDVTTGDTLCNSDHKVILERMEFPEPVIQIAVEPRSKADQEKMGIALGKLAAEDPSFRVETDAETGQTLISGMGELHLDIIVDRMKREFSVDCNVGKPQVAYRETIRGKSEVEGKFVRQSGGRGQYGHVWIKLEPSEPGAGFVFVDEVVGGVIPKEYISSVAKGIEEQMNSGVLAGYPVLDIKATLFDGSYHDVDSSEMAFKIAGSMAFKKGALEAQPVILEPMMKVEVTTPEDWMGDVVGDLNRRRGIIEGMDEGVAGLKIIRAQVPLSEMFGYATDLRSATQGRASYSMEFFEYAEVPKNIAEAIVAERGY
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_ECO24
Sequence: MQTSPLLTQLMEALRCLPGVGPKSAQRMAFTLLQRDRSGGMRLAQALTRAMSEIGHCADCRTFTEQEVCNICSNPRRQENGQICVVESPADIYAIEQTGQFSGRYFVLMGHLSPLDGIGPDDIGLDRLEQRLAEEKITEVILATNPTVEGEATANYIAELCAQYDVEASRIAHGVPVGGELEMVDGTTLSHSLAGRHKIRF
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: AMPA_ALIFM
Sequence: MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISGGYISSLLRRGDLEGKPGQMLLLHQVPNILSERVLLVGCGKERELGERQYKDIIKKTISTLNETGSMEAVCFLTELHVKGRDTYWKVRQAVESTKDSLYTFNQFKSNKPETRRPLRKLVFNVPTRRELNLGEKAIAHGLSIASGVKASKDLGNMPPNVANPAYLASQARRLADDYETVTTKIIGEEEMKKLGMTSYLAVGQGSHNESMMSIMEYKGHPDPTAKPIVLIGKGLTFDSGGISIKPSEGMDEMKYDMCGAASVFGAMKALAKLNLPLNVVGVLAGCENMPSSNSYRPGDILTTMSGQTVEVLNTDAEGRLVLCDALTYVERYEPECVVDVATLTGACVVALGHHISGLISNHNPLAHELINASEQSGDRAWRLPMAEEYNEQLSSPFADMGNIGGKAAGTITAGCFLSRFAKKYHWAHIDSAGTAWVSGANKGSTGRPVSLLVQFLLNRSGQENEE
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AP3S1_MOUSE
Sequence: MIKAILIFNNHGKPRLSKFYQPYSEDTQQQIIRETFHLVSKRDENVCNFLEGGLLIGGSDNKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHVDKVHNILAEMVMGGMVLETNMNEIVTQIDAQNKLEKSEAGLAGAPARAVSAVKNMNLPEIPRNINIGDISIKVPNLPSFK
What is the function of this protein?
Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated.  The complex is associated with the Golgi region as well as more peripheral structures.  It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes.  In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
What are the official names of this protein?
AP-3 complex subunit sigma-1, AP-3 complex subunit sigma-3A, Adaptor-related protein complex 3 subunit sigma-1, Sigma-3A-adaptin, Sigma3A-adaptin, Sigma-adaptin 3a.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes small subunit family.
What are the subcellular locations of this protein?
Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
Protein: DNLI3_HUMAN
Sequence: MSLAFKIFFPQTLRALSRKELCLFRKHHWRDVRQFSQWSETDLLHGHPLFLRRKPVLSFQGSHLRSRATYLVFLPGLHVGLCSGPCEMAEQRFCVDYAKRGTAGCKKCKEKIVKGVCRIGKVVPNPFSESGGDMKEWYHIKCMFEKLERARATTKKIEDLTELEGWEELEDNEKEQITQHIADLSSKAAGTPKKKAVVQAKLTTTGQVTSPVKGASFVTSTNPRKFSGFSAKPNNSGEAPSSPTPKRSLSSSKCDPRHKDCLLREFRKLCAMVADNPSYNTKTQIIQDFLRKGSAGDGFHGDVYLTVKLLLPGVIKTVYNLNDKQIVKLFSRIFNCNPDDMARDLEQGDVSETIRVFFEQSKSFPPAAKSLLTIQEVDEFLLRLSKLTKEDEQQQALQDIASRCTANDLKCIIRLIKHDLKMNSGAKHVLDALDPNAYEAFKASRNLQDVVERVLHNAQEVEKEPGQRRALSVQASLMTPVQPMLAEACKSVEYAMKKCPNGMFSEIKYDGERVQVHKNGDHFSYFSRSLKPVLPHKVAHFKDYIPQAFPGGHSMILDSEVLLIDNKTGKPLPFGTLGVHKKAAFQDANVCLFVFDCIYFNDVSLMDRPLCERRKFLHDNMVEIPNRIMFSEMKRVTKALDLADMITRVIQEGLEGLVLKDVKGTYEPGKRHWLKVKKDYLNEGAMADTADLVVLGAFYGQGSKGGMMSIFLMGCYDPGSQKWCTVTKCAGGHDDATLARLQNELDMVKISKDPSKIPSWLKVNKIYYPDFIVPDPKKAAVWEITGAEFSKSEAHTADGISIRFPRCTRIRDDKDWKSATNLPQLKELYQLSKEKADFTVVAGDEGSSTTGGSSEENKGPSGSAVSRKAPSKPSASTKKAEGKLSNSNSKDGNMQTAKPSAMKVGEKLATKSSPVKVGEKRKAADETLCQTKVLLDIFTGVRLYLPPSTPDFSRLRRYFVAFDGDLVQEFDMTSATHVLGSRDKNPAAQQVSPEWIWACIRKRRLVAPC
What is the function of this protein?
Isoform 3 functions as heterodimer with DNA-repair protein XRCC1 in the nucleus and can correct defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents.  Isoform 1 is targeted to mitochondria, where it functions as DNA ligase in mitochondrial base-excision DNA repair (PubMed:10207110, PubMed:24674627).
What are the official names of this protein?
DNA ligase 3, DNA ligase III, Polydeoxyribonucleotide synthase [ATP] 3.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
What are the subcellular locations of this protein?
[Isoform 1]: Mitochondrion. Note=Contains an N-terminal mitochondrial transit peptide. SUBCELLULAR LOCATION: [Isoform 2]: Mitochondrion. Note=Contains an N-terminal mitochondrial transit peptide. SUBCELLULAR LOCATION: [Isoform 3]: Nucleus. Note=Lacks the N-terminal mitochondrial transit peptide. SUBCELLULAR LOCATION: [Isoform 4]: Nucleus. Note=Lacks the N-terminal mitochondrial transit peptide.