PharMolix/UniProtQA huggingface dataset:
Protein: ACT_FUCVE
Sequence: MADEDVQALVVDNGSGMCKAGFARDDAPRAVFPSIVGRPKHPGIMVGMDQKDAYVGDEAQSKRGVLTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANKERMTQIMFETFNVPAMYVNIQAVLSLYASGRTTGCVLDSGDGVSHTVPIYEGYALPHAINRLDLAGRDLTDNLMKVLTERGYSFTTTAEREIVRDIKEKLTYVALDFDQEMKTAAESSQLEKSYELPDGNVIVIGNERFRCPEVLFQPSFIGMESSGIHDCTFKTIMKCDVDIRKDLYGNIVLSGGTTMFPGIGERMTKELTALAPSTMKIKVVAPPERKYSVWIGGSILASLSTFQQMWISKAEYDESGPSIVHRKCF
What is the function of this protein?
Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth.
What are the official names of this protein?
Actin.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: DB121_MACMU
Sequence: MKLLLLLLTVTLLLAQVTPVTKCWGKSGRCRTTCKKSEVYYILCKTEAKCCVDPKYVPVRSKLTDTNTSLESTSAV
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Beta-defensin 121, Defensin, beta 121.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: LOLB_SHISS
Sequence: MPQPDFRLIRLLPLAALVLTACSVTTPKGPGKSPDSPQWRQHQQDVRNLNQYQTRGAFAYISDQQKVYARFFWQQTGQDRYRLLLTNPLGSTELELNAQPGNVQLVDNKGQRYTADDAEEMIGKLTGMPIPLNSLRQWILGLPGDATDYKLDDQYRLSEITYSQNGKNWKVVYGGYDTKTQPAMPANMELTDGGQRIKLKMDNWIVK
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: RPN3_YEAST
Sequence: MASTAVMMDVDSSGVNDLHHSEKKYAEEDQVQELLKVLNEISKTTLTLDPRYIWRSLKDLSSLRNQELLNAETLCFTVNVLYPDSSSFKKNLLKFITSNHKSSVPGSAELRNSYPASFYSVNTEKKTIEVTAEINCFMHLLVQLFLWDSKELEQLVEFNRKVVIPNLLCYYNLRSLNLINAKLWFYIYLSHETLARSSEEINSDNQNIILRSTMMKFLKIASLKHDNETKAMLINLILRDFLNNGEVDSASDFISKLEYPHTDVSSSLEARYFFYLSKINAIQLDYSTANEYIIAAIRKAPHNSKSLGFLQQSNKLHCCIQLLMGDIPELSFFHQSNMQKSLLPYYHLTKAVKLGDLKKFTSTITKYKQLLLKDDTYQLCVRLRSNVIKTGIRIISLTYKKISLRDICLKLNLDSEQTVEYMVSRAIRDGVIEAKINHEDGFIETTELLNIYDSEDPQQVFDERIKFANQLHDEYLVSMRYPEDKKTQQNEKSENGENDDDTLDGDLMDDMSDISDLDDLGFL
What is the function of this protein?
Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
What are the official names of this protein?
26S proteasome regulatory subunit RPN3.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S3 family.
Protein: NUOD_BACC1
Sequence: MIRTEEMLLNVGPQHPSTHGVFRLVIKIDGEIIKEATPVIGYLHRGTEKIAESLQYTQIIPYTDRMDYLSAMTNNYVICHAVETMMGLEIPERAEYLRVLAMELGRIASHLVWWGTNLLDIGAVSPFLYAFREREMIINLLNELCGARLTFNYMRVGGVKWDAPDGWIEKVEEFVPYMREQLAGYHDLVSGNEIFLNRVKGVGIYSEEDAISYSLSGANLRCTGVNWDLRKDEPYSIYDRFDFDIPVGSVGDAWDRYVCRMKEIEESLKIVEQAVQQFPKEGAVLAKVPKIIKAPKGEAFVRIESPRGEIGCYIASDGKKEPYRLKFRRPSFYNLQILPKLLKGENIANLITILGGVDIVLGEVDG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CBLB_MOUSE
Sequence: MANSMNGRNPGGRGGNPRKGRILGIIDAIQDAVGPPKQAAADRRTVEKTWKLMDKVVRLCQNPKLQLKNSPPYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIYIDSLMKKSKRAIRLFKEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRITKADAAEFWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYVTGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESDGQGCPFCRCEIKGTEPIIVDPFDPRDEGSRCCSIIDPFSIPMLDLDDDDDREESLMMNRLASVRKCTDRQNSPVTSPGSSPLAQRRKPQPDPLQIPHLSLPPVPPRLDLIQKGIVRSPCGSPTGSPKSSPCMVRKQDKPLPAPPPPLRDPPPPPERPPPIPPDNRLSRHFHHGESVPSRDQPMPLEAWCPRDAFGTNQVMGCRILGDGSPKPGVTANSSLNGRHSRMGSEQVLMRKHRRHDLPSEGAKVFSNGHLATEEYDVPPRLSPPPPVTTLLPSIKCTGPLANCLSEKTRDTVEDDDDEYKIPSSHPVSLNSQPSHCHNVKAPVRSCDNGHCILNGTHGAPSEMKKSNIPDLGIYLKGGGSDSASDPVPLPPARPPPRDSPKHGSSVNRTPSDYDLLIPPLGEDAFDALPPSLPPPPPPARHSLIEHSKPPGSSSRPSSGQDLFLLPSDPFFDPTSGQVPLPPARRAAGDSGKANRASQDYDQLPSSSDGSQAPARPPKPRPRRTAPEIHHRKPHGPEAALENVDAKIAKLMGEGYAFEEVKRALEIAQNNVEVARSILREFAFPPPVSPRLNL
What is the function of this protein?
E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.  Negatively regulates TCR (T-cell receptor), BCR (B-cell receptor) and FCER1 (high affinity immunoglobulin epsilon receptor) signal transduction pathways.  In naive T-cells, inhibits VAV1 activation upon TCR engagement and imposes a requirement for CD28 costimulation for proliferation and IL-2 production.  Also acts by promoting PIK3R1/p85 ubiquitination, which impairs its recruitment to the TCR and subsequent activation.  In activated T-cells, inhibits PLCG1 activation and calcium mobilization upon restimulation and promotes anergy.  In B-cells, acts by ubiquitinating SYK and promoting its proteasomal degradation.  Slightly promotes SRC ubiquitination.  May be involved in EGFR ubiquitination and internalization.  May be functionally coupled with the E2 ubiquitin-protein ligase UB2D3.  In association with CBL, required for proper feedback inhibition of ciliary platelet-derived growth factor receptor-alpha (PDGFRA) signaling pathway via ubiquitination and internalization of PDGFRA (PubMed:29237719).
What are the official names of this protein?
E3 ubiquitin-protein ligase CBL-B, Casitas B-lineage lymphoma proto-oncogene b, RING-type E3 ubiquitin transferase CBL-B, SH3-binding protein CBL-B, Signal transduction protein CBL-B.
Protein: ATG18_PICGU
Sequence: MLKSQIAPIPSYESQPVHKPSSSVNFITFNQDGSCIAVGNNKGYSIFTTNPFTKCYDSPPGEAIGIVEMLYSTSLVVVVALGEETGSSPRKLKIINTKRGSTICDLVFPSTILKVKLTRSRMIVLLEEQIYLYDISTMKLLHTIETSPNMAGICAISADQGSTDTSNSADNSGSIGSGPASGSGAGSGSASMTSTDSTPDAQSHSYLAYPSPPKTAMHDSLLVAGINTNGGSHSKQNNIQSVSNAPNRVGDVIIFDTDSLQPLCVIEAHKSALAAISLSSDGRLLATASDKGTIVRVFSVSTGAKLYQFRRGTYPTKVYSVAFSPDNRYVVTTSASGTVHIFRLGEDESLESKHKRKRASRQHETIAEETSATQDLDDEIEDDGDDSDVDDVESLEVVPSKQRKLSQGSSNSYTSMNSGISGMSEDGKEPKIDPIVDHARLSVARMIRRSSQTLGRKAAQKMGDFLPSKFASILEPTRHFASLKIASASKDVKSIAVLDSQVVHDMVPQMFLHSKDAAPASALDTQSMTEMALLHIFVVTSDGYLYVYGLDPERGGDCILLQQHSFDI
What is the function of this protein?
The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).  Necessary for proper vacuole morphology.  Plays an important role in osmotically-induced vacuole fragmentation.  Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation-induced autophagy.  Involved in correct ATG9 trafficking to the pre-autophagosomal structure.  Might also be involved in premeiotic DNA replication (By similarity).
What are the official names of this protein?
Autophagy-related protein 18.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PROPPIN family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein.
Protein: JZT70_CHIGU
Sequence: MKFAVAIAFTLLVCVFAQEEEEPVTCGGKQCKPNSCCVQNSHGKGKDSPRCHPLGKLNNPCEVEPNENGIYSQHCPCGEGLSCTKVGEPNKLRCQEESGKSDKSKESQGSDESEESEESKESSG
What are the official names of this protein?
U33-theraphotoxin-Cg1c, U33-TRTX-Cg1c, Jingzhaotoxin-70, JZTX-70.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 32 family.
What are the subcellular locations of this protein?
Secreted.
Protein: R1AB_IBVK
Sequence: GGGGQSFLAADNAVLVSTQCYKRHSYVEIPSNLLVQNGMSLKDGANLYVYKRVNGAFVTLPNTLNTQGRSYETFEPRSDVERDFLDMSEEDFVEKYGKDLGLQHILYGEVDKPQLGGLHTVIGMYRLLRANKLNAKSVTNSDSDVMQNYFVLADNGSYKQVCTVVDLLLDDFLELLRNILNEYGTNKSKVVTVSIDYHSINFMTWFEDGSIKTCYPQLQSAWTCGYNMPELYKVQNCVMEPCNIPNYGVGITLPSGIMMNVAKYTQLCQYLSKTTVCVPHNMRVMHFGAGSDKGVAPGSTVLKQWLPEGTLLVDTDIVDYVSDAHVSVLSDCNKYKTEHKFDLVISDMYTDNDSKRKHGGVIANNGNDDVFIYLSSFLRNNLALGGSFAVKLTETSWHESLYDIAQDCAWWTMFCTAVNASSSEAFLIGVNYLGASVKVKVSGKTLHANYIFWRNCNYLQTSAYSIFDVAKFDLRLKATPVVNLKTEQKTDLVFNLIKCGKLLVRDVGNTSFTSDSFVCTM
What is the function of this protein?
NendoU is a Mn(2+)-dependent, uridylate-specific enzyme, which leaves 2'-3'-cyclic phosphates 5' to the cleaved bond.
What are the official names of this protein?
Replicase polyprotein 1ab, pp1ab, ORF1ab polyprotein.
Protein: TPIS_SULAC
Sequence: MKPPVILINYKAYENSYGKKSIEITKKIEKVSKEYGTEIIVSVPATMIHRISEESELTVFAQHVDSGEQGARTGAILPEMIKDAGARGSLLNHSERRIRLDEMAESLERIRVLNLESVVCVDRYELVLPVALLRPNAVLIEPPELIGTGIPVSKAKPEAITKAVEEIKKTKDVYLLAGAGITTGEDVFKAIELGADGIGAASAVMKAKEPEKVVEDFVKNAIKAMEKRGE
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_SHEAM
Sequence: MQVSVETTQGLERRLTISVPAEQIEKLVNESLKREAKRARIPGFRPGKVPMSVVSKRYGAAIRQDVTGEIMQRNFVEAIIAEKLNPAGAPTFMPGASDADKFEFVATFEVYPEVELKGLDAIEVEQPKADVTDADVDSMIETLRKQHATFDAAPRAAEEGDKVVINFVGSVDGEEFQGGKAEGFELQLGSGRMIPGFEEGIKGHKAGEEFEIDVTFPEEYHAENLKGKAAKFAITLTEVKAANLPEVNDEFAKLFGITDGGVEALKAEIRKNMSRELEQALKANVKEQVINGLLAANDIELPKALIDGEINVLRRQAVQRFGGNAANMPELPAELFAEQAERRVKVGLLLGEVIKSTELKVEEERVQALIASMASAYEDPAEVIEYYNGNKELMQNMRNVALEEQAVEALLKSAKVTEKEVAFEEFMNKATGRA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: EFC14_HUMAN
Sequence: MKKRKELNALIGLAGDSRRKKPKKGPSSHRLLRTEPPDSDSESSSEEEEEFGVVGNRSRFAKGDYLRCCKICYPLCGFVILAACVVACVGLVWMQVALKEDLDALKEKFRTMESNQKSSFQEIPKLNEELLSKQKQLEKIESGEMGLNKVWINITEMNKQISLLTSAVNHLKANVKSAADLISLPTTVEGLQKSVASIGNTLNSVHLAVEALQKTVDEHKKTMELLQSDMNQHFLKETPGSNQIIPSPSATSELDNKTHSENLKQDILYLHNSLEEVNSALVGYQRQNDLKLEGMNETVSNLTQRVNLIESDVVAMSKVEKKANLSFSMMGDRSATLKRQSLDQVTNRTDTVKIQSIKKEDSSNSQVSKLREKLQLISALTNKPESNRPPETADEEQVESFTSKPSALPKFSQFLGDPVEKAAQLRPISLPGVSSTEDLQDLFRKTGQDVDGKLTYQEIWTSLGSAMPEPESLRAFDSDGDGRYSFLELRVALGI
What are the official names of this protein?
EF-hand calcium-binding domain-containing protein 14.
Protein: ABNB_ASPOR
Sequence: MVLVATLFSLFTVSLCRSIPRSSPSSSPYTQATDLKIHDPTVINANGAYYAYGVGEHIVIHQAPGLAGPWKQIGSVLDKDSIIPKGDRAKPWAPTTIEVKGTFYCYYSVSNAGCRDSAIGVATSQSPGPGGWTDHGAIVQSGTGQGSDEHPFNEVNAIDPAVLVTGDKGHLVFGSYWSGIWQVPLNEDFSSVGNTTGLNAHHLAKHPKTERVNSQDQNPDPLCRDSSGRRPVEGAYISYHAPYYYLWLSWGQCCDYDPNNLPPSGEEYSIRVGRSESPHGPFVDKQGKELTQGGGELIYGSNNDVYAPGGQGVITVETGDILYYHYSLYRYSTHSLYTFANLDFNQGCTLFIQ
What is the function of this protein?
Endo-1,5-alpha-L-arabinanase involved in degradation of pectin.  Its preferred substrate is linear 1,5-alpha-L-arabinan (By similarity).
What are the official names of this protein?
Probable arabinan endo-1,5-alpha-L-arabinosidase B, Endo-1,5-alpha-L-arabinanase B, ABN B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 43 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RR12_LOBMA
Sequence: MPTIKQLIRNTRQPIRNVTKSPALRGCPQRRGTCTRVYTITPKKPNSALRKVARVRLTSGFEITAYIPGIGHNLQEHSVVLVRGGRVKDLPGVRYHIVRGTLDAVGVKDRQQGRSKYGVKKPK
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits (By similarity).
What are the official names of this protein?
30S ribosomal protein S12, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MOAA_THEVO
Sequence: MVLTDLYGRPVLSLRIQLNTTCNFNCFFCHMEGTEISGEALKPEEIERVVKIAHKFGVNKIKLTGGEPTLRRDLIDIVKRIRKYITGNISMTTNGVMLPILAYELKKAGLDRVNISMHAFDEDTFQAITGVNSRDRIIKAIDAANEAGLTPVKINFVVLRDLNVDQIPDMIELAAEKHAILQLIEYETTREGESSKEYLKYHMPLDSLEKEIADKALSIERNELHNRPRYIIRTQAGEVKVEFVKPQRNPDFCAHCTRLRITSEGEFKTCLMRSDTNVKFKGINDEKTISELFRQAVLRREPYWRPGDEVRQNEVLAKSIIQNKRK
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
Probable GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: NPVF_RAT
Sequence: MEIISSKRFILLTLATSSFLTSNTLCSDELMMPHFHSKEGYGKYYQLRGIPKGVKERSVTFQELKDWGAKKDIKMSPAPANKVPHSAANLPLRFGRNIEDRRSPRARANMEAGTMSHFPSLPQRFGRTTARRITKTLAGLPQKSLHSLASSELLYAMTRQHQEIQSPGQEQPRKRVFTETDDAERKQEKIGNLQPVLQGAMKL
What is the function of this protein?
Neuropeptide RFRP-1 acts as a potent negative regulator of gonadotropin synthesis and secretion.  Neuropeptides NPSF and NPVF efficiently inhibit forskolin-induced production of cAMP (By similarity).  Neuropeptide NPVF blocks morphine-induced analgesia.
What are the official names of this protein?
Pro-FMRFamide-related neuropeptide VF, FMRFamide-related peptides.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS17_PSEPG
Sequence: MAEAEKTVRTLTGRVVSDKMDKTITVLIERRVKHPIYGKYVKRSTKLHAHDESNQCKIGDKVSIRETRPLAKTKSWALVEVLERAVEV
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: Y171_AQUAE
Sequence: MEEEEVYIDVNSPVALKVHPSKDLMKFLLSENANLKMASFFTEFEKGFMDIIVGIKIRYKDLSRELLKFVVLNIGNLANEYGKEIRAVFGGLSFKEYLEREKYSYPYSGEKLFQEKISINGTLLLLEVYVKEENYTLICREEGSSNYLIKAIRKVEGPYEALKILEKAKESIKNRDFVSLRKLFSPYEVDFFELYSVFLKGKDTTKLKKLEKEIHELPYMLINGKITYEEYKKRIREIEKEIGLSE
What are the official names of this protein?
Uncharacterized protein aq_171.
Protein: RLMN_STRA3
Sequence: MSKKTDTPDYKPSIYSLTRDELIAWAIEHGEKKFRASQIWDWLYKKRVQSFDEMTNISKDFIALLNENFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQYYGLSVCVTTQVGCNIGCTFCASGLIKKQRDLNNGEITAQIMLVQKYFDERGQGERVSHIVVMGIGEPFDNYTNVLKFLRTVNDDNGLAIGARHITVSTSGLAHKIREFANEGVQVNLAVSLHAPNNELRSSIMRINRSFPLEKLFAAIEYYIETTNRRVTFEYIMLNGVNDTPENAQELADLTKKIRKLSYVNLIPYNPVSEHDQYSRSPKERVEAFYDVLKKNGVNCVVRQEHGTDIDAACGQLRSNTMKRDRQKAKVGR
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2267_ARCFU
Sequence: MEECLKMIYTRRSIRVYSDRQISDEDIEKILKAAMLAPSAGNEQPWHFIVVRDREMLKKMSEAFTFGQMLPNASAAIVVCADPKLSKYPYDMWVQDCSAATENILLAARCLGIGSVWLGVYPREERMKALRELLGIPENIVVFSVVSLGYPKDEKDFYEADDRFNPDRIHREKW
What are the official names of this protein?
Putative NADH dehydrogenase/NAD(P)H nitroreductase AF_2267.
What is the protein family that this protein belongs to?
Belongs to the nitroreductase family.
Protein: RET4_HORSE
Sequence: MEWVWALVVLAALGSAGAERDCRVSSFRVKENFDKARFSGTWYAMAKKDPEGLFLQDNIVAEFSVDEYGQMSATAKGRVRLLNNWDVCADMVGTFTDTEDPAKFKMKYWGVASFLQKGNDDHWIIDTDYDTYAVQYSCRLLNLDGTCADSYSFVFARDPNGFPPEVQRIVRRRQEELCLARQYRLISHNGYCDGKSDRNLL
What is the function of this protein?
Retinol-binding protein that mediates retinol transport in blood plasma.  Delivers retinol from the liver stores to the peripheral tissues.  Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane.
What are the official names of this protein?
Retinol-binding protein 4, Plasma retinol-binding protein, PRBP, RBP.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ALCA_BORPA
Sequence: MNREIYDFVAIGIGPFNLSLASLSAPLRGVRTLFLDKKSGFDWHPGMLIETSTLQNPFLADLVSLADPRSEYSYLNYCKLTNRIYSYYMRENHYLSRAEYTRYCQWVAARLPNLRFGCDVQGVLHDPESHSYLVTGQHTMSGQRFMFRCRKLVLGLGSQPYLPACCDRRAAPFIHSADYLRHKYELQGRASITIVGSGQSAAEVFHDLLRESGRHDYSLAWITRSPRFFQMENTKLTLELISPDYTEYFHDLPEARRQEILTQQNSLYKGINASLINQIYDLLDEKVHDGDNRYTLLTNSELRACRYDPLQERFQLDFQHLDCDRPFSHATDGLVLATGYSHEIPACINPIHDRIAWNADGSYRIGRNYAIDHEGSEIFVQNTGLLSHGVTNPDLGFCCYRNSQILRELTGTEHYRIETRTALQEFSPPADGVLKHRPARRAERRPTVAARPLMDIHRATL
What are the official names of this protein?
Alcaligin biosynthesis enzyme.
What is the protein family that this protein belongs to?
Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.
Protein: MUTS_SHIFL
Sequence: MSAIENFDAHTPMMQQYLKLKAQHPEILLFYRMGDFYELFYDDAKRASQLLDISLTKRGASAGEPIPMAGIPYHAVENYLAKLVNQGESVAICEQIGDPATSKGPVERKVVRIVTPGTISDEALLQERQDNLLAAIWQDSKGFGYATLDISSGRFRLSEPADRETMAAELQRSNPAELLYAEDFAEMSLIEGRRGLRRRPLWEFEIDTARQQLNLQFGTRDLVGFGVENAPRGLCAAGCLLQYAKDTQRTTLPHIRSITMEREQDSIIMDAATRRNLEITQNLAGGAENTLASVLDCTVTPMGSRMLKRWLHMPVRDTRVLLERQQTIGALQDFTAELQPVLRQVGDLERILARLALRTARPRDLARMRHAFQQLPELRAQLETVDSAPVQALREKMGEFAELRDLLERAIIDTPPVLVRDGGVIASGYNEELDEWRALADGATDYLERLEVRERERTGLDTLKVGFNAVHGYYIQISRGQSHLAPINYMRRQTLKNAERYIIPELKEYEDKVLTSKGKALALEKQLYEELFDLLLPHLEALQQSASALAELDVLVNLAERAYTLNYTCPTFIDKPGIRITEGRHPVVEQVLNEPFIANPLNLSPQRRMLIITGPNMGGKSTYMRQTALIALMAYIGSYVPAQKVEIGPIDRIFTRVGAADDLASGRSTFMVEMTETANILHNATEYSLVLMDEIGRGTSTYDGLSLAWACAENLANKIKALTLFATHYFELTQLPEKMEGVANVHLDALEHGDTIAFMHSVQDGAASKSYGLAVAALAGVPKEVIKRARQKLRELESISPNAAATQVDGTQMSLLSVPEETSPAVEALENLDPDSLTPRQALEWIYRLKSLV
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: LPXE_HELPJ
Sequence: MKKFLFKQKFCESLPKSFSKTLLALSLGLILLGVFIPFPKVPKHQSVPLALHFTEHYARFIPTILSVAIPLIQRDAVGLFQVANASIATTFLTHATKRALNHVTINDQRLGERPYGGNFNMPSGHSSMVGLAVAFLMRRYSVKKYLWLLPLIPLTMLARIYLDMHTIGAVLAGLGTGMLCVGLFTSPKNLN
What is the function of this protein?
Removes the 1-phosphate group from tetra- and probably hexaacylated lipid A species (PubMed:16740959).  Absence of the 1-phosphate group renders the bacteria partially resistant to host-derived cationic antimicrobial peptides (CAMP), allowing it to camouflage itself from the host innate immune response, and plays a role in the long-term colonization of the host's stomach (PubMed:22216004).
What are the official names of this protein?
Lipid A 1-phosphatase.
What is the protein family that this protein belongs to?
Belongs to the lipid A LpxE 1-phosphatase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LPXK_KORVE
Sequence: MNPLSALFGAGVATRNAMFDRSLLKQQRLRGPVVSVGNLCVGGTGKTPFTQLLGDLLMQREIDFDVLSRGYGRESTEIKIVELDGSPNEFGDEPLLLAKYFAAKKPENPPRVIVGADRYEAGRFAEQKFGPRLHLLDDGFQHRGLARDFDIVLLAPDDADQVLLPVGRLREPLTALKRAHAVVATDEVKIEAFPVMPPLVWRVERDIALPEQLSRNARVLAFCAIARPHRFFTDLRRHGLEPVAELTFRDHHRYSAADIEKIVREISSSRADCCVTTIKDMMNLGELVHRLAPIYAVRLSLKLRDADAALDEIIKIIERRQG
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: CDC2_OXYRB
Sequence: MDQYEKVEKIGEGTYGVVYKARDKVTNETIALKKIRLEQEDEGVPSTAIREISLLKEMQHGNIVRLQDVVHSEKRLYLVFEYLDLDLKKHMDSCPDFAKDPRMIKRFLYQILRGIAYCHSHRVLHRDLKPQNLLIDRQTNALKLADFGLARAFGIPVRTFTHEVVTLWYRAPEILLGSRHYSTPVDVWSVGCIFAEMVNQKPLFPGDSEIDELFKIFRTLGTPNEETWPGVTSLPDFKSSFPKWISKDLSAVVPNLDPAGIDLLNKMLCLDPSKRITARNALEHEYFKDIGFVP
What is the function of this protein?
Plays a key role in the control of the eukaryotic cell cycle.  Component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II.
What are the official names of this protein?
Cell division control protein 2 homolog, p34cdc2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Protein: ASSY_CHLL2
Sequence: MSKEKIALAYSGGLDTSVMIKWLKDKYDAEIVAVTGNLGQQKEIENLESKAYSTGASAFRFVDLRKTFVEEYIWRALKAGALYEDVYPLATALGRPLLAKALVDVALEENCTMLAHGCTGKGNDQVRFEVTFASLAPHLKILAPLREWEFTSREAEIAYALEHNIPVSATKKSPYSIDENIWGISIECGVLEDPMVTPPEDAYQITTSPENAPDTPASVEIEFVKGIPVALDGERMSGLDMIQKLNDIGAANGIGRLDMIENRVVGIKSREIYEAPAATILHFAHRELERLTLEKTVFQYKKNISQDYANIIYNGTWFSPMRKALDAFVDETQKPVTGLVRLKLYKGGISLLGRNSPNSLYNEELATYTEADTFNHKAAAGFIHLYGLGMKTFSQVNPGL
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1947_ANADF
Sequence: MTDGEGEAGDRRARGREAERIAEAFLSRAGFEILDRNHATRRGEVDLVCREGSVVCFVEVRSRTSTAQGGPEETVGRGKARRVVAAATDWALRNGGLEQEMRFDVVAVTFEEAGPRVALYRGAFDGEGKPGLW
What are the official names of this protein?
UPF0102 protein Anae109_1947.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: CONA1_HUMAN
Sequence: MGPGERAGGGGDAGKGNAAGGGGGGRSATTAGSRAVSALCLLLSVGSAAACLLLGVQAAALQGRVAALEEERELLRRAGPPGALDAWAEPHLERLLREKLDGLAKIRTAREAPSECVCPPGPPGRRGKPGRRGDPGPPGQSGRDGYPGPLGLDGKPGLPGPKGEKGAPGDFGPRGDQGQDGAAGPPGPPGPPGARGPPGDTGKDGPRGAQGPAGPKGEPGQDGEMGPKGPPGPKGEPGVPGKKGDDGTPSQPGPPGPKGEPGSMGPRGENGVDGAPGPKGEPGHRGTDGAAGPRGAPGLKGEQGDTVVIDYDGRILDALKGPPGPQGPPGPPGIPGAKGELGLPGAPGIDGEKGPKGQKGDPGEPGPAGLKGEAGEMGLSGLPGADGLKGEKGESASDSLQESLAQLIVEPGPPGPPGPPGPMGLQGIQGPKGLDGAKGEKGASGERGPSGLPGPVGPPGLIGLPGTKGEKGRPGEPGLDGFPGPRGEKGDRSERGEKGERGVPGRKGVKGQKGEPGPPGLDQPCPVGPDGLPVPGCWHK
What are the official names of this protein?
Collagen alpha-1(XXIII) chain.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein; Extracellular side.