PharMolix/UniProtQA huggingface dataset:
Protein: SYI_FRATF
Sequence: MSDYKDTLNLPKTSFSMKGNLANKEPMILNKWEKQGIYKKIREHFAGREKFVLHDGPPYANGSIHVGHAVNKILKDIIIKSKTLSGYDAPFTPTWDCHGLPIELQVEKKHGKAGQSISEDDFRKECRKYAKKQVEIQKKDFKRLGVLGDWEQPYLTMNFDYEANMIRTLAKIIENGHLSKGFKPVHWCTDCGSALAEAEVEYADKVSPAIDVKFKIKDKDKLAQAFGLDSLNHDAFAIIWTTTPWTLPANQAIAVNNQLNYSLIKIEDFYIILAENLVEQTLKRYAIENAQIIATTTGNKLTGIIAEHPFYSRHVPILHGDHVTDDSGTGLVHTAPTHGVDDFTLGKEHNLSMEIFVKGNGCYSENTKLFAGEFIFKASDRIIELLGEKKRLMNSDKIKHSYPHCWRHKTPLMFRATPQWFISMEKQGLRDKALQTIKETSWAPSWGQARIEGMVKDRPDWCISRQRTWGVPLPLFIHKETEELHPNTIEILHKVAEKIEKDGIEAWFNADDCEFITETAQYKSVKDTLDVWFDSGSSSMCILDLDKRLSYPADLYLEGSDQHRGWFQTSLLVAMSAKGSQPYKEVFTHGFVVDEHGRKMSKSLGNVTSPQDIYNTLGADILRLWTASTDYKSEMAVSDQILKRTADTYRRLRNTARFLLSNLDGFNPVTDIIEFDKLVKLDQWAIAKTKEFQDKIIEAYDKYQTHTVAQLIHHFCSIEMGSFYLDIIKDRQYTAKTDGHPRKSAQTAIYHIVHALVRWMAPILSFTADEIWDATPKTTDLPIQLCEWYTGLKSFDQDAELDLEYWAKIQEIRSEVNRVLEIKRNEDVIKASLEAEITIYADKYNYKLLEKLGNELRFLLISSKADLKVIEESTSSSIAANILGLLIEITKIEEPKCERCWHRSSTVGDNPQYKDICSRCVENITTEAGESREFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR7_XANOR
Sequence: MPVSTTLLQSDLPGLPLRHRGKVRDVFDIPRDRLPADAPPGDYLLMVATDRLSAFDVVLPDPIPGKGEMLCQVSNFWFHKTEHLMPNHLVDIRVEQVLPEGVDPALYAKRAVVTRKLKPVPVEAIARGYLIGSGWKDYQRTGKISGIELPDGLRQAEKLPEPIFTPSTKAAVGDHDENIDFDAMVKTVGAELAERVRDATLRIYRFAADFAAECGILLADTKFEFGTDADGRLYVMDEMLTPDSSRYWPADQYELGTSPPSYDKQFVRDYLETLDWGKTAPGPSLPADVIDRTRAKYAEALQRLAGISVD
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: ATPB_GEOSW
Sequence: MTKGRVIQVMGPVVDVKFENGHLPAIYNALKIQHKARNENEVDIDLTLEVALHLGDDTVRTIAMASTDGLIRGMEVIDTGAPISVPVGEVTLGRVFNVLGEPIDMQGEIPDDARRDPIHRPAPKFEELATEVEILETGIKVVDLLAPYIKGGKIGLFGGAGVGKTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYHEMKDSGVISKTAMVFGQMNEPPGARMRVALTGLTMAEYFRDEQGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTATGSITSIQAIYVPADDYTDPAPATTFSHLDATTNLERKLAEMGIYPAVDPLASTSRALAPEIVGEEHYQVARKVQQTLQRYRELQDIIAILGMDELSDEDKLIVHRARRIQFFLSQNFHVAEQFTGQPGSYVPIKETVRGFKEILEGKYDHIPEDAFRLVGRIEEVVEKAKQMGVEV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HPXO_ACIAD
Sequence: MNVVIIGAGMGGLTTGIALKKFGHQVTIFEQAEQILPVGAAISLWSNGVKCLNYLGLNEQIAKLGGQMDNLAYVDGLTGDVMTEFSLQPLIEEVGQRPYPVSRAELQNMLMDEFGREDIHLGKRMVALQQKDDQVEIEFADGSSILADVLVGADGTHSITRTYVLGEKVERRYAGYVNWNGLVDISSDLAPADQWTTYVGEGKRASLMPVADNRFYFFLDVPLEAGLENDKCKYKETLQSYFKGWCPQVQTLIERLDPQKTNRVEICDIEPFAQFYKGRVVLVGDAAHSTTPDIGQGGCQAMEDAIYLARSLQINTLSVEDALRRYQEKRNQRANELVLRARKRCDVTHMKDEAVTTAWYAELRQEKGLHIMNGIISNIVGNPLD
What is the function of this protein?
Catalyzes the hydroxylation of urate to 5-hydroxyisourate (HIU).  Is involved in the urate degradation pathway to allantoin.
What are the official names of this protein?
FAD-dependent urate hydroxylase, Flavoprotein urate hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent urate hydroxylase family.
Protein: RUTE_ECO7I
Sequence: MNEAVSPGALSTLFTDARTHNGWRETPVSDETLREIYALMKWGPTSANCSPARIVFIRTAEGKERLRPALSSGNLQKTLTAPVTAIVAWDSEFYERLPQLFPHGDARSWFTSSPQLAEETAFRNSSMQAAYLIVACRALGLDTGPMSGFDRQHVDDAFFTGSTLKSNLLINIGYGDSSKLYARLPRLSFEEACGLL
What is the function of this protein?
May reduce toxic product malonic semialdehyde to 3-hydroxypropionic acid, which is excreted.
What are the official names of this protein?
Probable malonic semialdehyde reductase RutE.
What is the protein family that this protein belongs to?
Belongs to the nitroreductase family. HadB/RutE subfamily.
Protein: EFTU2_PSET1
Sequence: MAKAKFERVKPHVNVGTIGHVDHGKTTLTAAITNVLAKVYGGVAKDFASIDNAPEERERGITISTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLSRQVGVPYIIVFMNKCDMVDDEELLELVEMEVRELLSEYDFPGDDLPLIQGSALKALEGEKEWEDKIVELANALDSYIPEPERDIDKAFIMPIEDVFSIQGRGTVVTGRVEAGIIRINDEIEIVGIRDTTKSICTGVEMFRKLLDEGRAGENIGALLRGTKREDVERGQVLAKPGSIKPHTTFESEVYVLSKDEGGRHTPFFKGYRPQFYFRTTDVTGDVQLPEGVEMVMPGDNVKMTVTLIAPIAMDEGLRFAIREGGRTVGAGVVANIVA
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu 2, EF-Tu 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYR_NEIG2
Sequence: MNLHQTVEHEAAAAFAAAGIAGSPVVLQPTKNAEHGDFQINGVMGAAKKAKQNPRELAQKVADALAGNAVIESAEVAGPGFINLRLRHEFLAQNIHAALNDARFGVAKTAQPQTVVIDYSSPNLAKEMHVGHLRSSIIGDSISRVLEFTGNTVIRQNHVGDWGTQFGMLVAYLVEQQKDNAAFELADLEQFYRAAKVRFDEDPAFADTAREYVVKLQGGDETVLALWKQFVDISLSHAQAVYDTLGLKLRPEDVAGESKYNDDLQPVADDLVQKGLAVEDDGAKVVFLDEFKNKEGEPAAFIVQKQGGGFLYASTDLACLRYRIGRLKAGRLLYVVDHRQALHFEQLFTTSRKAGYLPENAKAEFIGFGTMMGKDGKPFKTRSGDTVKLVDLLTEAVERATALVKEKNPELGADEAAKIGKTVGIGAVKYADLSKNRTSDYVFDWDAMLSFEGNTAPYLQYAYTRVQSVFRKAGEWDATAPTVLTEPLEKQLAAELLKFENVLQSVADTAYPHYLAAYLYQAATLFSRFYEACPILKAEGASRNSRLQLAKLTGNTLKQGLDLLGIDVLDVM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_ENT38
Sequence: MALNLQDKQAIVAEVSEVAKGALSAVVADSRGVTVDKMTELRKAGREAGVYMRVVRNTLLRRVVEGTQFECLKDAFVGPTLIAYSMEHPGAAARLFKDFAKANAKFEVKAAAFEGELIPASQIDRLATLPTYEEAIARLMATMKEASAGKLVRTLAAVRDAKEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: NGR1_YEAST
Sequence: MMSNVANASQRQENPYIIPLPPSSTVETSTEPPRTLWMGDLDPSFDEATIEEIWSKLDKKVIVKLIRAKKNLLIPCSSTSSSNNNTSEENAENQQSASNSTDQLDNSQMININGISFIDPSTTQLHHAGYCFVEFETQKDAKFALSLNATPLPNFYSPTTNSQTNPTFKRTFRLNWASGATLQSSIPSTPEFSLFVGDLSPTATEADLLSLFQTRFKSVKTVRVMTDPLTGSSRCFGFVRFGDEDERRRALIEMSGKWFQGRALRVAYATPRNNMMLQLQEQQQQQQQLQQQHQQLDQEDNNGPLLIKTANNLIQNNSNMLPLNALHNAPPMHLNEGGISNMRVNDSLPSNTYNTDPTNTTVFVGGLVPKTTEFQLRSLFKPFGPILNVRIPNGKNCGFVKFEKRIDAEASIQGLQGFIVGGSPIRLSWGRPSSSNAKTNSTIMGASQYMSSNGLRAPSAASSVDNSKQILEQYAEDKRRLFLHQQQQQQQQQQQDGNFSMEQMAHNNYYNYNNYDYHRNKNGSHSDLVNLQRSNVPYMQEDGALYPHQYSSPSYSLHPTGNQFSNATNNLPQFGNAMSISMQLPNGNSNKTASSMNTNPNTNMIMNSNMNMNMNVNPVPYGMGNGANMYDVSRMMTPPLNIAPNSNNSKSSIMNKHPNRNNVPPIHPSLLH
What is the function of this protein?
May be an RNA-binding protein involved in control of an RNA processing pathway that influences the regulation of cell growth in early log phase.  Can bind to RNA and single-stranded DNA but not double-stranded DNA.
What are the official names of this protein?
Negative growth regulatory protein NGR1, RNA-binding protein RBP1.
Protein: RL2_ANADE
Sequence: MALKEYKPTSPARRHMTVADFAEITKAKPEKRLTKPVRKSGGRNAHGKVTTRHIGGGHKRRYRVIDWRRDKDGVPAKVAAIEYDPNRTARIALLHYLDGEKRYILAPVGVAVGDTLVSGADVDIRPGNALPVRTIPLGTVIHNVETAPGSGAKMIRTAGSFGQLMAKEGGYAQIRLPSGEVRKVLQDCKATIGQLGNVESSSVRVGKAGKSRWLGIRPTVRGLAMNPVDHPHGGGEGKSGQGNPHPVSPWGQKTKGLKTRNNRRTDKFIVTRRRPGVRNTQR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: Y386_MYCLE
Sequence: MRDHLPPGLPPDPFADDPCDPSAALDAVEPGQPLDQQERIAVEADLADLAVYEALLAHKGIRGLVVCCDECQQDHYHDWDMLRANLLQLLIDGTVRPHEPAYDPEPDSYVTWDYCRGYADASLNQATSDADGYRRRH
What are the official names of this protein?
Uncharacterized protein ML0386.
What is the protein family that this protein belongs to?
To M.tuberculosis Rv3412.
Protein: RLR5_PLAVT
Sequence: MRGAFYMAITLFLARSRSATAIDQLDVSQTYLNVGAIGGEGTKLTPKRYLRDGLALSAANEERVKANVLSKSAKTLAAEGEDWLRLSLGTGGHSHPPKSKRKVNLSLAKSKGGISKKVTTPKQRVYKRHFVSIDPRLPGYLKVHQTFRKIFGMPHEMSLTEAVLMYGMVNWKHGSSPATKKIIDSLLRLAERSNLADFERALDPMFVRIASLEEMQNEYFHSLQTMYAKVYAFCHAHPADCTNKKAVSPLERMIKAQRANVILPPVTH
What is the function of this protein?
Effector that acts as a broad suppressor of cell death to interrupt plant immunity.  Inhibits cell death induced by cell death-inducing proteins, including the PAMP elicitor INF1 from P. infestans.
What are the official names of this protein?
Secreted RxLR effector protein 5.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host nucleus.
Protein: SYP_STRPJ
Sequence: MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLPLANRVIEKAKNIMRQEFEKIGAVEMLAPTLLSAELWRESGRYETYGEDLYKLKNREKSDFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDAYSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSARTDLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATNEYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVGNDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVRNAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFKLGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRYAWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKFSDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GACH_DICDI
Sequence: MSGVGGESVHLRRSSTTATTTGSSKSSLNISKSVSPTGNKAVSPMSSPNSLQSGATPTIAQLQSLLKQQQQPNHSITTNNNNNKSVSVEIDDLKSQLQHSNINDTFNEDEEIEEVTDEVIINHDYHSSEDEYEDDEDEDENNNSVNNNSNNNSNNNNNNNTSISSAHSCESIAEEEELTASPILSRQYSYTIGHGTKPDVVLSIGGGFHSSPRSNRSESTIVHEDDLTNQNDKVINAKDKISSDYKRMMEDPEAFRNEKLKQRKSKFFTKKDLEEIPFNPSSGTQLRSTLFQQFMNEKIQMISENPEKYKSELMKFYKQNLKPQVPKSPQSSGSLSTHSDKLKTSSSLQRSRSVSQPPVVTGNSKNAIGSLDTILEKERKRDGNQDRQLPILFTKCVDFLSNDEALKTEGLFRVAGNSSEVEDLMKSILLYGSDIPSNCCYHVVSNMLKKFLRQLSTPVFTFKYHNDFIQTMKLNNDEERIKAIKEILKLIPPVNQLLIKELMKFLVKVTSFSNVNMMHAHNLGLMFGPNMLKAPSDSEMNAISMLDAGNQVITLLIENYNLFYDN
What is the function of this protein?
Rho GTPase-activating protein involved in the signal transduction pathway.
What are the official names of this protein?
Rho GTPase-activating protein gacH, GTPase activating factor for raC protein H.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YMGG_ECOUT
Sequence: MKKKILAFGLISALFCSTPAMADMNRTTKGALLGAGVGLLTGNGVNGVLKGAAVGAGVGAVTEKGRDGKNARKGAKVGAAVGAVTGVLTGNGLEGAIKGAVIGGTGGAILGKMK
What are the official names of this protein?
UPF0757 protein YmgG.
What is the protein family that this protein belongs to?
Belongs to the UPF0757 family.
Protein: PYRC_ANAPZ
Sequence: MVSERQTWSLLQGGQCNEYTVAYINARIIDPASGTDYKGYLLTRGKEILDFGPGFFDPNGAAFAASEVVDCNGHVLMPGIVDLHVHLREPGGEHKETVDTGSRAAAAGGVTTVVCQPNTIPRLENVLVAKYLKMRALESSCVNIEFYGAVTKSDGELCDMASLKDAGALGFTDDGLPVMNALYMKRAFEYAQDLDVVVAQHAEDCNLSDGGCINEGLVSRELGLKGIPDISESIMVSRDIQLLREVPGAHYHVLHISTKKALDIVRAAKREGLRVTCEVTPHHFLLNESAVLEHGTMAKMNPPLRTEEDRLSMISGLEDGTIDCIATDHAPHAAQEKTRPISCCAFGIVGLETLLPLSLELYHNAGMSLMDVLSKLTSKPAEIVRLPRGKIAKGLVADLVIFDLEHVWTIDTAKFSSKSKNSPFQGRKVKGKVLRTVVSGKTVYRAE
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: PORL_BUCAP
Sequence: MKNHKSLAILIPMLFAGSTAVNAIEIFNKNGNKLELYGSINPNHNFSNEFLSTKISSKEDNTNAILGLSGKIKITDKLSSYAQIEYKNNFFMPEDLMNKQQPNTVRLGYAGLKYGNLGSIDYGRNYGVIHDAQSLTDHVPYINKKSIFAYNDNYMVGRNHSLLTYRNNNVFGLVDGISFALQYQDEIKNRDLNKGKSSSGWGASLKYESDSGLTAVGSCFTSERMISSNKKDLKNTSVDSYGLGFKYDANNVYVAAFYGSARNLMPYNMHISDSFINETQNIEAIAEYSFDSGFHPSLSYLDSKGQNSNSPKKELDLAKQINISTRYEFNKNVSTYMNYKINLLKENDFISQNQIPTDNTIGAGVVYQF
What is the function of this protein?
Forms pores that allow passive diffusion of small molecules across the membrane.
What are the official names of this protein?
Porin-like protein BUsg_347.
What is the protein family that this protein belongs to?
Belongs to the Gram-negative porin family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: GLUQ_PROMM
Sequence: MAKSSALPDHLYEQMEVGQRLRNQGYRGRFAPSPTGPLHLGNLCTALVSWLQARLANGAWLLRVDDLDQPRNRVGAVESLQQDLHWLGLEWDGPVVFQSRRRGIYNSFLSALRRQGKLYACRCSRRMLADISAPAGRHLVYPGTCRDLELFWGWHEGRLPSWRLRVSKEFSHTSGDVILRRADGFIAYHLATVVDELTLGISEVVRGEDLLDAMNAQLALINAISERPVIYRHVPLLCDDQGRKLAKREGHAGLDSLRSEGLGPSHVVGWLAASQSLVPFGAELTAGELLSELKKKEGVLKSVLKP
What is the function of this protein?
Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp).  Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.
What are the official names of this protein?
Glutamyl-Q tRNA(Asp) synthetase, Glu-Q-RSs.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
Protein: NARG_BRASZ
Sequence: FSPIDRYNDNHTQETYEDREWENVYRSTHGVNCTGSCSWKDGIVTWEGQELNYPTTGPDMPDFEPRGASYSWYLYSANRGVLWSMWQEELQNNESPLDAWKSSWQEVNELIAASNVYTVKTYGPDRVAGFSPIPAMSMVSYASGARTPDAHFFTEVRVVSVSPDFAESTKLCDLWLAPKQGTDAAMALAMGHVMLREFHLDNPSDYFLNYCRQYTDFPFLVTLSKQKGDQFVADRAADLVDALGQENNPEWKPVLWNENTNDFATPHGTMGSRGKWNLEQRLEDEETGEKLSVLGIEDEIGTVRLQLADGSTALVTTVYDLTMANYGLERGLGGQEPKDFNDDVPFTPAWQEKITGVPRELIIQIAREFADNADKTHGRAVLNLVLLVGAQGVNGGGWAHYVGQEKLRPAEGWQTIAMAKHMNSTSYFYNHSSQWRYETVTAQELLSPMADKYQHHGDYNVLAARMGWLPSAPQLGTNPLRQAGMSPVDYTVKFAAEQPENGKNHPRNLFVWRSNLLGSSGKGHEYMLKYLLGTENGIQGKQGGVKPEEVEWKLSSTCLYSDIVLPTATWYEKDDMNTSDMHPFIHPLSAAVDPAWESKSDWDIFTSLSKKFSEVCVGHLGKETDVVTLPIQHDSAAELAQPLDVKDWKGECEPIPGKTMPQIHVVERDYPATYERFTSIGPLMEKGIAWNTQSEMDLLRAWAALSEFTGRDHTHLALNKEDEKFRDIQAQPRTVITSPAFTGSEKQSFYLDHDMMKDFGESLLVYRPPIDTRKSRPEVEGKEITLNYLTPHNKGGPIVWISETDARDLGIEDNDWIEVFNSNGALTARVPAGMTMMYHAQERGGIHNSVTRPTHMIGGYAQLAYGFNYYGTVGSNRDEFVVVRNINWLDGEGNDQVQESVK
What is the function of this protein?
The nitrate reductase enzyme complex allows Bradyrhizobium sp.  USDA 3045 to use nitrate as an electron acceptor during anaerobic growth.  The alpha chain is the actual site of nitrate reduction.
What are the official names of this protein?
Respiratory nitrate reductase alpha chain, Respiratory membrane-bound nitrate reductase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm.
Protein: ISPG_HAEDU
Sequence: MLKEVPIKRRQSTKIYVGNVPVGGDAPIAVQSMTNTRTTDIEATIAQIKALERVGADIVRVSVPTMDAAEAFKVIKQQVNVPLVADIHFDYRIALKVAEYGVDCLRINPGNIGNEERIRAVVDCAKDKNIPIRIGVNAGSLERDLQEKYGEPTPQALLESALRHVEILDRFNFDQFKVSVKASDVFLAVESYRLLAKAIKQPIHLGITEAGGARAGSVKSAIGLGLLLSEGIGDTLRVSLAADPVDEVKVGFDILKSLRIRSRGINFVACPTCSRQEIDVIATVNALEQRLEDILTPMDVSIIGCVVNGPGEALVSDLGVTGSNKMSGFYLDGVRQKERFDNDKLIDQLEAKIRAKVAQQHHRIAIEQI
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: SC6A9_BOVIN
Sequence: MAAAQGPVAPSSLEQNGAVPSEATKKDQNLKRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMELSFGQFASQGCLGVWRISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTPVLPWTYCNNPWNTPDCMSVLDNPNITNGSQPPALPGNVSQALNQTLKRTSPSEEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWVVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFIRGVTLEGAFTGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLVTMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQKKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVIISCIMCVSIMYIYGHQNYFQDIQMMLGFPPPLFFQICWRFVSPAIIFFILIFSVIQYQPITYNQYQYPSWRVRIGFLMALSSVICIPLYALFQFCRTDGDTLLHRLKNATKPSRDWGPALLEHRTRRYAPTTTPSPEDGLEVQPLHPDKAQIPMVGSNGSSRFQDSRI
What is the function of this protein?
Sodium- and chloride-dependent glycine transporter which is essential for regulating glycine concentrations at inhibitory glycinergic synapses.
What are the official names of this protein?
Sodium- and chloride-dependent glycine transporter 1, GlyT-1, GlyT1, Solute carrier family 6 member 9.
What is the protein family that this protein belongs to?
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A9 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UBC15_SCHPO
Sequence: MPSSASEQLLRKQLKEIQKNPPQGFSVGLVDDKSIFEWEVMIIGPEDTLYEGGFFHATLSFPQDYPLMPPKMKFTTEIWHPNVHPNGEVCISILHPPGDDKYGYEDAGERWLPVHSPETILISVISMLSSPNDESPANIDAAKEFRENPQEFKKRVRRLVRRSIEMI
What is the function of this protein?
Catalyzes the covalent attachment of ubiquitin to other proteins.  Has a role in the formation of chromatin structures that influence the localization of transcriptional silencing factors.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 15, E2 ubiquitin-conjugating enzyme 15, Ubiquitin carrier protein 15, Ubiquitin-protein ligase 15.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: OTX1_RAT
Sequence: MMSYLKQPPYGMNGLGLAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQSGNGTKSRPVKKKSSPVRESSGSESSGQFTPPAVSSSASSSSSASSASANPAAAAAAGLGGNPVAAASSLSTPTASSIWSPASISPGSAPASVSVPEPLGAPSNASCMQRSVAAGAATAATSYPMSYGQGRSYGQGYPAPSSSYFGGVDCSSYLAPMHSHHHPHQLSPMAPSSMAGHHHHHPHAHHPLSQSSGHHHHHHHHHHHQGYGGSGLAFNSADCLDYKEPAAAAASSAWKLNFNSPDCLDYKDQASWRFQVL
What is the function of this protein?
Probably plays a role in the development of the brain and the sense organs.  Can bind to the BCD target sequence (BTS): 5'-TCTAATCCC-3' (By similarity).  May play a role in the specification or differentiation of neurons in the deep layers of the cerebral cortex, and also in cerebellar regionalization during early development.
What are the official names of this protein?
Homeobox protein OTX1, Orthodenticle homolog 1.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family. Bicoid subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRM2_HHV11
Sequence: MAGREGRTRQRTLRDTIPDCALRSQTLESLDARYVSRDGAHDAAVWFEDMTPAELEVVFPTTDAKLNYLSRTQRLASLLTYAGPIKAPDDAAAPQTPDTACVHGELLAAKRERFAAVINRFLDLHQILRG
What is the function of this protein?
Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging.  Forms a tripartite terminase complex together with TRM1 and TRM3 in the host cytoplasm.  Once the complex reaches the host nucleus, it interacts with the capsid portal vertex.  This portal forms a ring in which genomic DNA is translocated into the capsid.
What are the official names of this protein?
Tripartite terminase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae TRM2 protein family.
What are the subcellular locations of this protein?
Host nucleus. Note=Found associated with the external surface of the viral capsid during assembly and DNA packaging, but seems absent in extracellular mature virions.
Protein: PURL_SULTO
Sequence: MKITLSSYEMELVRKKLAREPNEAEWLTIDALWSEHCSYKSSKVFLRSFPSEGEKVLMGIEDWQDAGALDVGDGWAIVLKLESHNHPSAIDPFNGAATGVGGIIRDIISKGAKPIALLDMIRVGNLSNPRNKWLLKNIIAGIGFYGNSIGVPVVGGELDFDDSYNDNPLVDVAGVGIVRKDKIVPSVVKEPGLKIVIVGLTGLDGLGGASFASRKLSGEDEIGAVQIADPFAGKIVLDVTLEIADKVEAIKDLGGGGLVVGVTEMANGLGAIVNLDKVPLRVKDLKPEEILVSETQERMLFAVKEENVNEVCKAFEYYDYPCAVIGEFVKEPYIKFLYGGKEIVSLPSDLLLSPPRFIWEIKKPKLIKSDKKPEVGLEESIRAILSRIISKEWAYSQFDYEVGTSTVLKPGEADSALISLPNGKLLALKGDANPDLCAEDSYECGKSIVAEAYRNLASVGAIGIGVVDHLQFGDPKKPEVYYSFVEAIRGIAEASKFFSTPIVGGKVSFYNENKEGKAIKPTPLIVMAGLIKDKFLRNKVVEDSYITLIGFTRDEMRGSLFGKIFGNYGEVPKARLNEDYLASQLVVNLINDEKIFFAKDINKGGLIASLFSILVKGMGVEIETSSIPSDTDDWIPKLYSENGGRFIVLTNDPEYIIRKSKGIHISVIGKITKDQGIIKIDNKEINVNKEIDNYYNYLYEVMS
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HISZ_RUBXD
Sequence: MRSRAARKFSTTPGTRDVLPPESTRLLDVQRRVLGRFRLHGFREVITPALEYAEVVEEARLRDSAFKLFDPDNQMLLLRPEMTTPIARLVSQRLRNAPPPFKLSYSLPVYRRSEVGRGQSAEFHQAGVEVVGSASPGEDAGTIALLVEALEAAGLGPGEDFMVVLGQAAFYRGFLERSCPEVAPALLSALAGKDLVRVEELSRRLPDAVAAGARGIPRLVGPASDGAVLEEAERYASGGGGAALENLRAILELLGAHGRLEAVMLDLGLIGRHDYYTGAVYEVYAAGLGFTVANGGRYDNLLRRFGEPLPATGFAISLERLVSVLPPERPAPLLVLVGEDAEAVRAARALRGEGVPVLHVSGGLAPEEAERYARSVDARWVGYPAPGGVKLREVGEGGFWLLAVEEAARRVLG
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.