PharMolix/UniProtQA huggingface dataset:
Protein: MNMA_SHEPW
Sequence: MTSIDPTHLGKKVIVGMSGGVDSSVSAYLLMKQGYQVEGLFMKNWEEDDTDEYCAAADDLKDAQAVCDKLGIKLHTVNFASEYWDNVFEYFLAEYKAGRTPNPDIMCNKEIKFKAFLEFADEILDADYIAMGHYVRRRDIDGTSQMLRGVDGNKDQSYFLYTLSHEQVARSLFPVGELEKSEVRDIAKEMGLITHDKKDSTGICFIGERKFTDFLSTFLPAQPGNIETSEGEVIGQHQGLMYHTLGQRKGLGIGGLKNSSEDPWYVVEKDLVRNVLVVGQGGNHPRLMSNGLLANQLHWVDRKGPAEGAKITLKTRYRQHDVPCTVTYDSDDQIRVIFDEAVAAVTPGQSAVFYDGEICLGGGIIDVLIRD
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS21_KORVE
Sequence: MAEVKLQEGESLENALRRFKRKVQQEDIIKEVKRHSFYLKPGEKKRVKEALARKRSRKKARKEQD
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: FABH_BRUAB
Sequence: MIRSVVRGIGSALPKRVMKNTDFEGIVETSDEWIVQRTGIRERHIAGEGETTVSLGAAAARAAIENAGLQPSDIDLVLLATSTPNNTFPASAVAIQRELGITRGFAFDLQAVCSGFIYAITTADLYIRGGMARRVLVIGAETFSRILDWTDRTTCVLFGDGAGAIVLEAAEGHGLTSDRGILAANLRSDGNHKEKLYVDGGPSTTQTVGHLRMEGREVFKHAVGMITDVIEASFEATGLTAEDIDWFVPHQANKRIIDASAKKLHIAEEKVVITVDRHGNTSAASVPLALATAVADGRIKKGDLVLLEAMGGGFTWGAVLVRW
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1226_FRATO
Sequence: MILTTADTLGKREIIEYKGLVTGIIVRTPTITQGILGGLKNIIGGKNTSYTNVCKEARLHAEQEMINQAKELGANAIVAIRYDSSSLGGNTSGTEVFCYGTAVVVR
What are the official names of this protein?
UPF0145 protein FTH_1226.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: YKIE_ECOLI
Sequence: MGWSLCFWHVSVRMTHDVVCYY
What are the official names of this protein?
Protein YkiE.
Protein: NUOD_WOLSU
Sequence: MQIPNRLQPFYENLVFERHDNQMVINFGPQHPSAHGQLRLILELEGEKVTRAVPDVGYLHRGMEKMGENMIYNEFIPTTDRMDYIAASSNNHAFALTVEKLLGIEVPRRAKVIRMMIVELNRIISHLFWLATHALDVGAMSIFLYCFREREFAMDLMEDYCGARLTHSSIRIGGVPLDLPAGWLEKLKSFLEKMPENIALYEGLLSENRIWKMRLENVGIITPEMAKSWGCSGVALRGSGIQWDLRKEQPYELYDEVEFDIPVSDSGDSYGRYKLYMEEMRQTVKILHQLIEMYPSTSSEIMAHAPQYISAPKEQIMTQNYSLMQHFVLVTQGMRPPVGEVYCATESPKGELGFFIRSEGEPYPYRLKIRAPSFYHTGILQDLLPGGYIADVVTIIGNLNIVFGEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NUOH_CHESB
Sequence: MESFVTLYVLPGLLILLKSVALIVILLVGVAYILYADRKIWAAVQLRRGPNVVGPWGLFQAFADLFKFVFKEPVIPSGANKGVFLLAPVVAAGLALAAWAVIPVSEGWAIANINVGILYVFAIASLEVYGVIMAGWASNSKYPFLGALRSAAQMVSYEVSIGFVIVTVLLAVGSLNLTDIVLSQRDGLGTMVGLPNSFLDWHWLALFPMFIIFFISALAETNRPPFDLVEAESELVAGHMIEYSSTPFLLFFLGEYVAIVLMCALTTILFLGGWLPPFDFAPFTWVPGVVWFVLKLVAVFFMFALVKSFVPRYRYDQLMRLGWKVFLPISLFMVVATAAFLKFTGLV
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRPD_CALMQ
Sequence: MRPLLEKIARGLELSLEEAYNAALAILKMEAGEAETAALLMGLRVRGERAFEVAGFAKALRETCLRIPVNDPYVIDTAGTGGDGLRTMNVSTISALLAAYLGVKVLKHGNRSVSSSSGSADFLEALGFNISVKPETALLMLNNHRFSFAFAPMYHPAMKNVMPVRRRLGIRTIFNLVGPLANPGLVRRQVLGVAEAGIMGVMAEAAGLIGYDHLLLVHGEPGIDEVSVFGRTMIYEVKGNSIDKYVIEPPELGLRIHELRDVVVSNPMESIEKAKRGLMGVDEAALDFIAANTAMALYVAGKVKDPRDGVEAVKQIAGNSNDFWSYVNNVAAVSRRDSA
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: RNH_SULNB
Sequence: MQKQARKQITLYSDGSSLGNPGPGGYGGILEYKGSRKEYFGGEEETTNNRMELRGVIEGLKLLKEPCDVEVVSDSSYVVKAINEWLESWIRRDFKKVKNVDLWKAYIEAAAPHHVHGTWVRGHDGHPENERCDELARNEAERIKASL
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEL_ECOLI
Sequence: MNKVAQYYRELVASLSERLRNGERDIDALVEQARERVIKTGELTRTEVDELTRAVRRDLEEFAMSYEESLKEESDSVFMRVIKESLWQELADITDKTQLEWREVFQDLNHHGVYHSGEVVGLGNLVCEKCHFHLPIYTPEVLTLCPKCGHDQFQRRPFEP
What are the official names of this protein?
Uncharacterized protein YbeL.
Protein: RS11_SHEB8
Sequence: MAKVPSRSPRKRVRKQVADGMAHIHASFNNTIVTITDRQGNALSWATSGGSGFRGSRKSTPFAAQVAAERAGAAAQDYGLKNLEVFVKGPGPGRESAIRALNAVGYKITNITDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: SYE1_CERS4
Sequence: MPAASDKPVVTRFAPSPTGYLHIGGGRTALFNWLYARGRKGTFLLRIEDTDRERSTPEATDAILRGLTWLGLDWDGEVVSQFARKDRHAEVAREMLERGAAYKCFSTQEEIEAFRESARAEGRSTLFRSPWRDADPTSHPDAPFVIRMKAPRSGETVIEDEVQGTVRFQNETLDDMVVLRSDGTPTYMLAVVVDDHDMGVTHVIRGDDHLNNAARQTMVYEAMGWEVPVWAHIPLIHGPDGKKLSKRHGALGVEEYQAMGYPAAGMRNYLARLGWSHGDDEFFTSEQAMDWFDLGGIGRSPARLDFKKLESVCGQHIAVMEDAELMREIAAYLAAARKPALTDLQAARLEKGLYALKDRAKTFPELLEKARFALESRPIVADDAAAKALDPVSRGILRELTPMLQAASWSKQDLEAILTAFASEKGMGFGKLAAPLRTALAGRTVTPSVYDMMLVIGRDETIARLEDAAAA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 1, Glutamyl-tRNA synthetase 1, GluRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIF3L_NEOFI
Sequence: MSYEERVNAHPNLGDESDVEEEALVNDYREQVNFDDGMSELERTTSLGTGSQTQDLQAQLAAAATPLEYQATLETKFASYDNYCSLFHYILNSEGPVELEVPSYYWAWDVIDEFIYQFESFCRYRNRVARSGSNEEEAQLLRENPNTWGCYSVLNVLYSLIQKSQINEQLAAIKRGEDPLAFAGEYGSRPLYKMLGYFSIIGLLRVHCLLGDFSLALKTLDDIEMNKKAMFARVMAAHFTTYYYVGFSYMMMRRYGDAIRMFSHILVYVSRTKNFQKGGNSYDAIAKKNDQMYALIAICVALHPTRLDDTIHSALREKYGEQLLRLQHGGPDALPLFEELFRSACPKFISPTPPDFDNPALNIDPVDHHTAIFMDEVKNTLYNPTIRSYLKLYTTMDLKKLAGFLEVQPEVLRSWLLVNKQRSRQVRWVEGGLLEGEVVSANDLDYALENDLIHVSETKAGRRLVDWYLRNLARVY
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit L, eIF3l.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit L family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y025_SIFVH
Sequence: MIYTIRISKKYFYKLVNMCKEYKSYRECVMKELEKKYQVKIYNSTRSHDMNIKNDLIPKVINIIFYDQENERLEELAQRLGKTKYEIIISLFK
What are the official names of this protein?
Uncharacterized protein 25.
Protein: KTNA1_SALSA
Sequence: MSLHEINENVKLAREYALLGNYSSAIVCYRGVLEQIKKYLFTVRDSSFQQKWQQVWQEINEENNQVQEIMRTLESFQLETTPSKPPSNQDGINDIWPVQVERRSSPLPVRRPPVPYKDSKPHNNRLSVAGVRAQHRQSPRGANGDRAKPLKGKEKKEAKPKDDKNKAEVSEKEVKRFDGQGYDKDLIEALERDIISQNPNVKWDDIADLEEAKKLLKEAVVLPMWMPEFFKGIRRPWKGVLMVGPPGTGKTLLAKAVATECRTTFFNVSSSTLTSKYRGESEKLVRILFEMARFYAPTTIFIDEIDSMCSRRGTSEEHEASRRVKAELLVQMDGVGGASDNEDPSKMVMVLAATNFPWDIDEALRRRLEKRIYIPLPSAKGRVELLRINLKELELANDVDMAKIAEQSEGYSGADITNVCRDASLMAMRRRIEGLTPEEIRNISRAEMHMPTTMEDFESSLKKVSKSVSASDLEKYEKWIEEFGSC
What is the function of this protein?
Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner.  Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
What are the official names of this protein?
Katanin p60 ATPase-containing subunit A1, Katanin p60 subunit A1, p60 katanin.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, spindle. Note=Predominantly cytoplasmic. Also localized to the interphase centrosome and the mitotic spindle poles. Enhanced recruitment to the mitotic spindle poles requires microtubules and interaction with katnb1.
Protein: DJB12_HUMAN
Sequence: MESNKDEAERCISIALKAIQSNQPDRALRFLEKAQRLYPTPRVRALIESLNQKPQTAGDQPPPTDTTHATHRKAGGTDAPSANGEAGGESTKGYTAEQVAAVKRVKQCKDYYEILGVSRGASDEDLKKAYRRLALKFHPDKNHAPGATEAFKAIGTAYAVLSNPEKRKQYDQFGDDKSQAARHGHGHGDFHRGFEADISPEDLFNMFFGGGFPSSNVHVYSNGRMRYTYQQRQDRRDNQGDGGLGVFVQLMPILILILVSALSQLMVSSPPYSLSPRPSVGHIHRRVTDHLGVVYYVGDTFSEEYTGSSLKTVERNVEDDYIANLRNNCWKEKQQKEGLLYRARYFGDTDMYHRAQKMGTPSCSRLSEVQASLHG
What is the function of this protein?
(Microbial infection) In case of infection by polyomavirus, involved in the virus endoplasmic reticulum membrane penetration and infection (PubMed:21673190, PubMed:24675744).
What are the official names of this protein?
DnaJ homolog subfamily B member 12.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family. DNAJB12/DNAJB14 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein. Note=Localizes to the endoplasmic reticulum membrane (PubMed:21150129, PubMed:21148293, PubMed:24732912, PubMed:27916661). When overexpressed, forms membranous structures in the nucleus (PubMed:24732912).
Protein: EIF3B_LODEL
Sequence: MSINEEEYLRLEEEIDLGDIDFTDLEEQYEADLGYDNYVIVDGAPIAPEAKVPILIKVLRKLFSTAGEIVEGDEGIFMPMENGKSKGFLFIQYKNVADADTAIKKLNGKKLDAQHRLLVNRLSDIEKYGSVSGEFKEPEIEPFQSHGFLQSWLQDEQGKDQIVLHFNESVGVYWNKKTSEPEPVIEPRRGFTSKYAKFSPKGTYLFSIHPQGIQAWGGADFHRIKRFFHNQVRLVDFSPNEKYMVTLSPLPITLPDSTAERAQFPFGPESEGHKLVIWDMETGEPARTFALPPHLENQKEMQWPLVKWSFDDKYCARQGPDALAIYETPSFQLLEKKLVKIDGIQEFEWAPAGVKLHNSKEANEHLLSYWTPESANQTARVAIMQIPSRQVLRTVNLFQVSDCKMHWQSEGKLLCVKVDRHTKSGKTLFSNLDFFKVTERDIPVEKLELKDVIVNFSWEPKSERFVTISRLDDGNPNPAIPKNSITFYAVEEGKGKNANSKYKAYKQIENKHSNTVFWSPKGRYVAVATISRSSGEIEFYDVSFDDETSKKAAPANVKLLKTDKYSGMTNIAWDPSGRFLAAWSSSWLHTIENGYRIYEFTGNLLRDDSVDQFKEFIWRPRPESLLTSSDRKKVRSNLREYSAQFEEFDAMEADAAVREAILARRKALEDWRAYRAKHAGKKVQTSKVQAEVIEEIKEEIVEEKEEIVE
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit B, eIF3b, Eukaryotic translation initiation factor 3 90 kDa subunit homolog, eIF3 p90, Translation initiation factor eIF3, p90 subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXH_NEIM0
Sequence: MDLHNIREDYSKRELSEGDCADNPIEQFERWLDEAVRAEVNEPTAVNVAAVDGRGRPNSRMVLLKEVNSEGFVFFTNYHSRKGRSLDAHPFAAMTFFWPELERQVRVEGRVERLAEKLSDEYFESRPYQSRLGAWASAQSEVIPNKAVLVAKAAAVGLKHPLHVPRPPHWGGYIVIPDLLEFWQGRPSRLHDRIQYRLLDGGWIRERLSP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: TRPA_CERS4
Sequence: MTRIDDTFRRLRAEGKKAFVAYIMAGDPDLETSLAVMRGLPEAGVDIIELGMPFTDPMADGPTIQTAGQRALEGGQTLTRTLEMVRAFRAENAETPIVMMGYYNPIYARGVETFLAEATEAGIDGLIVVDLPPEEDAELCLPAQAAGLNFIRLATPTTDSRRLPKVLQNTSGFVYYVSITGITGAAAAQAADVAPEVARIKAATDLPVIVGFGITTPEAAQDLAGIADGCVVGSAIVKLVGEGRPVAEVLDRVAALAAGAHAA
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: Y1387_STAAB
Sequence: MDMNFDLYMNGVVEQARNEIESAGYEQLTTAEDVDKVLKQDGTTLVMINSVCGCAGGIARPAASHALHYDVLPDRLVTVFAGQDKEATQRAREYFEGYAPSSPSFALVKDGKITEMIERHQIEGHDVMNVINQLQTLFNKYCEER
What are the official names of this protein?
UPF0403 protein SAB1387c.
What is the protein family that this protein belongs to?
Belongs to the UPF0403 family.
Protein: Y736_ARCFU
Sequence: MCYTLGFVTGVLFLLFDRSPFVRFHAVQSTLTFSTITALVILLPVLPGGALLSRVVMAFSIILWAFCIVKASRGEAFKLPIFGDIAEEQLSLNYT
What are the official names of this protein?
UPF0132 membrane protein AF_0736.
What is the protein family that this protein belongs to?
Belongs to the UPF0132 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FLAD_VIBC3
Sequence: MAVNVNTNVAAMTAQRYLTGATNAQQTSMERLSSGFKINSAKDDAAGLQISNRLNVQSRGLDVAVRNANDGISIAQTAEGAMNETTNILQRMRDLSLQSANGSNSKSERVAIQEEITALNDELNRIAETTSFGGNKLLNGTFSTKSFQIGADNGEAVMLTLKDMRSDNRMMGGTSYVAAEGKDKDWKVQAGANDITFTLKDIDGNDQTITVNAKEGDDIEEVATYINGQTDMVKASVNEKGQLQIFAGNNKVTGDVAFSGGLAGALNMQAGTAETVDTIDVTSVGGAQQSVAVIDSALKYVDSHRAELGAFQNRFNHAISNLDNINENVNASKSRIKDTDFAKETTALTKSQILSQASSSVLAQAKQAPNAALSLLG
What is the function of this protein?
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.  FlaD is not essential for flagellar synthesis and motility (By similarity).
What are the official names of this protein?
Flagellin D.
What is the protein family that this protein belongs to?
Belongs to the bacterial flagellin family.
What are the subcellular locations of this protein?
Secreted. Bacterial flagellum.
Protein: RS20_RHIL3
Sequence: MANTTSAKKATRKIARRTDVNKARRSRVRTFVRQVEEAIASGDAAKAKEAFLAAQPELARAASKGVLHSNTASRKVSRLAARVKALSVTTTA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: SRP54_STRMU
Sequence: MAFESLTERLQGVFKNLRGKRKLSEKDVQEVTKEIRLALLEADVALPVVKEFIKRVRKRAVGHEVIDTLDPSQQIIKIVNEELTAVLGSETAEIEKSSKIPTIIMMVGLQGAGKTTFAGKLANKLVKEENARPLMIAADIYRPAAIDQLKTLGQQINVPVFDMGTEHSAVEIVSQGLAQAKENRNDYVLIDTAGRLQIDEKLMTELRDIKALANPNEILLVVDSMIGQEAANVAREFNQQLEVTGVILTKIDGDTRGGAALSVRQITGKPIKFTGTGEKITDIETFHPDRMSSRILGMGDLLTLIEKASQDYDEQKSAELAEKMRENSFDFNDFIEQLDQVQNMGSMEDILKMIPGMANNPALANVKVDEGEIARKRAIVSSMTPEERENPDLLTPSRRRRIASGSGNTFVNVNKFIKDFNQAKKMMQGVMSGDMNKVMKQMGINPNNMPKNMDSSALEGMMGQGGMPDMSELSGTNMDVSQMFGGGLKGKVGEFAMKQSMKKMAKRMKKAKKRKK
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes.  The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
What are the official names of this protein?
Signal recognition particle protein, Fifty-four homolog.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. SRP54 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=The SRP-RNC complex is targeted to the cytoplasmic membrane.
Protein: UNG_STAES
Sequence: MKWSEVFHDITTRHDFQAMHDFLEKEYTTQTVYPDKQNIYQAFDLTPFEDIKVVILGQDPYHGPNQAHGLAFSVQPHAKFPPSLRNMYQELENDIGCHRTSPHLQDWAREGVLLLNTVLTVRQGEAHSHRNIGWETFTDEIIQAVSNYREHVVFILWGRPAQQKERFIDTSKHLIIKSPHPSPLSAFRGFFGSKPYSTTNNYLKSKGKTPVQWCES
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAL_CAMJJ
Sequence: MKNFSLWCDFIENSFLDNEFLNLLSHGINGATSNPAIFKNAILNSPIYKDKILKLKGKKTKDIYEELAISDIQKAADKLAPLFYQKNDGFISIEIDPRLHDNTTLSLGEAKRLYSAISKENVMIKIPATKASYEVMYELMKNGISVNATLIFSLEQSQKCFEALNAGLVEFRKNNIALKEQNTRTPQAVISIFVSRFDRLLNPKAKEQNRIGILNANLAYNNIYSKNEPNIRALFASTGVKGDDLPKDYYIKELLFENSVNTAPLDAIEAFKGKMHFKKPLMNFEIYTELNQIISQSEREKACNDLLSDGLEQFCIAFEDILKAL
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CM310_CONRE
Sequence: MLNMGVVLFICLVLFPLATLQLDADQPVERHAENKRNLNPHERREIIMLALRGVNCCHPNLCIGRSALGRKCTCCG
What are the official names of this protein?
Conotoxin reg3.10, Rg3.10.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: VIF_HV1V9
Sequence: MENRWQVMIVWQVDRMRIKTWNSLVKHHMYVSKKAKKWVYRHHYESTNPKTSSEVHIPVGDARLVITTYWGLHTGERDWHLGHGVSIEWRQERYSTQIDPDLADQLIHLHYFDCFSDSAIRKAILGHRVSPICDYQAGHRKVGSLQYLALTALISPKRTKPPLPSVRKLVEDRWNKPQKTRGHRGSHTMNGH
What is the function of this protein?
Counteracts the innate antiviral activity of host APOBEC3F and APOBEC3G.  Forms a complex with host APOBEC3F and APOBEC3G thus preventing the entry of these lethally hypermutating enzymes into progeny virions.  Recruits an active E3 ubiquitin ligase complex composed of elongin BC, CUL5, and RBX2 to induce polyubiquitination of APOBEC3G and APOBEC3F.  In turn, they are directed to the 26S proteasome for degradation.  Vif interaction with APOBEC3G also blocks its cytidine deaminase activity in a proteasome-independent manner, suggesting a dual inhibitory mechanism.  May interact directly with APOBEC3G mRNA in order to inhibit its translation.  Seems to play a role in viral morphology by affecting the stability of the viral nucleoprotein core.  Finally, Vif also contributes to the G2 cell cycle arrest observed in HIV infected cells.
What are the official names of this protein?
Virion infectivity factor, Vif, SOR protein.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group Vif protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Virion. Note=In the cytoplasm, seems to colocalize with intermediate filament vimentin. A fraction is associated with the cytoplasmic side of cellular membranes, presumably via the interaction with Pr55Gag precursor. Incorporated in virions at a ratio of approximately 7 to 20 molecules per virion.
Protein: BBC3B_HUMAN
Sequence: MKFGMGSAQACPCQVPRAASTTWVPCQICGPRERHGPRTPGGQLPGARRGPGPRRPAPLPARPPGALGSVLRPLRARPGCRPRRPHPAARCLPLRPHRPTRRHRRPGGFPLAWGSPQPAPRPAPGRSSALALAGGAAPGVARAQRPGGSGGRSHPGGPGSPRGGGTVGPGDRGPAAADGGRPQRTVRAAETRGAAAAPPLTLEGPVQSHHGTPALTQGPQSPRDGAQLGACTRPVDVRDSGGRPLPPPDTLASAGDFLCTM
What is the function of this protein?
Does not affect cell growth.
What are the official names of this protein?
Bcl-2-binding component 3, isoforms 3/4, JFY-1, p53 up-regulated modulator of apoptosis.
What are the subcellular locations of this protein?
Note=Contrary to isoforms 1 and 2, isoform 3 does not localize to the mitochondria.
Protein: RL31_PROM0
Sequence: MPKSEIHPKWYPDAKVICNGEVVMTTGSTQPELHVDVWSGNHPFFTGTQKILDTEGRVDRFMKKYGMGSANSSESKDQKEEKDSKK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: RL29_STRP3
Sequence: MKLQEIKDFVKELRGLSQEELAKKENELKKELFDLRFQAAAGQLEKTARLDEVKKQIARVKTVQSEMK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: DER_VIBCM
Sequence: MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGQAKLGEHEFIVIDTGGIDGSEEGVETKMAQQSLAAIDEADVVLFMVDGRAGLTVADEAIAQHLRRIEKPAILVVNKVDGIDADAASAEFWQLGMDQMYQIAAAHGRGVGALIDRVLNPFAEQMESEQAQLEDLTNEEDPEEEQLEYSEEEAEAEYKRLQDLPIKLAIIGRPNVGKSTLTNRILGEERVVVYDMPGTTRDSIYIPMKRDEREYVLIDTAGVRRRKRINETVEKFSVVKTLQAIEDANVVLLVVDARENISDQDLSLLGFALNSGRSIVIAVNKWDGLSFDVKEHVKKELDRRLGFVDFARIHFISALHGTGVGHLFESVQEAYRSATTRVGTSVLTRIMKMATDDHQPPMVRGRRVKLKYAHAGGYNPPIIVIHGNQVNELPDSYKRYLMNYYRKSLEIMGTPIRIQFQNSENPFEGKTNKMTLSQERQRKRLMSMVKNRRK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.