PharMolix/UniProtQA huggingface dataset:
Protein: PGRP1_HUMAN
Sequence: MSRRSMLLAWALPSLLRLGAAQETEDPACCSPIVPRNEWKALASECAQHLSLPLRYVVVSHTAGSSCNTPASCQQQARNVQHYHMKTLGWCDVGYNFLIGEDGLVYEGRGWNFTGAHSGHLWNPMSIGISFMGNYMDRVPTPQAIRAAQGLLACGVAQGALRSNYVLKGHRDVQRTLSPGNQLYHLIQNWPHYRSP
What is the function of this protein?
Innate immunity protein that plays several important functions in antimicrobial and antitumor defense systems.  Acts as a pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria and thus provides bactericidal activity (PubMed:9707603).  Forms an equimolar complex with heat shock protein HSPA1A and induces programmed cell death through apoptosis and necroptosis in tumor cell lines by activating the TNFR1 receptor on the target cell membrane (PubMed:21247889, PubMed:26183779).  In addition, acts in complex with the Ca(2+)-binding protein S100A4 as a chemoattractant able to induce lymphocyte movement (PubMed:26654597).  Mechanistically, this complex acts as a ligand of the chemotactic receptors CCR5 and CXCR3 which are present on the cells of the immune system (PubMed:30713770).  Promotes also the activation of lymphocytes that become able to kill virus-infected cells as well as tumor cells by modulating the spectrum of their target-cell specificity (PubMed:29083508, PubMed:28977785).  Induction of cytotoxicity on monocyte surface requires interaction with TREM1 receptor (PubMed:28977785, PubMed:25595774).
What are the official names of this protein?
Peptidoglycan recognition protein 1, Peptidoglycan recognition protein short, PGRP-S.
What is the protein family that this protein belongs to?
Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic granule.
Protein: NADA_BACAA
Sequence: MSILEKVQPIETMLPERYYTMSTEDMEKRVREIKEKMGETLFIPGHHYQKDEVVQFSDAAGDSLQLAQVAASNKEAKYIVFCGVHFMAETADMLTTDEQVVILPDMRAGCSMADMADIEQTERAWEELTKLFGDTMIPLTYVNSTAAIKAFCGRNGGATVTSSNAKQMVSWAFTQKERLVFLPDQHLGRNTAYDLGIPLDKMAVWDPHTDSLEYDGDIEEIQVILWKGHCSVHQNFTVKNIENVRKNHPDMNIIVHPECCYEVVAASDYAGSTKYIIDMIESAPSGSKWAIGTEMNLVNRIIQQHPDKEIVSLNPFMCPCLTMNRIDLPHLLWALETIERGEEINVISVDKQVTEEAVLALNRMLERV
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HMDH_HALS3
Sequence: MPDDASDLADRVQAGDLRLYELDDETDADTAAAARRAVLERETDADTDALGAFAFDADQAADTAVENLTGGAQLPLGVAGPVALSGGAADGEYYLPMATTEGALVASVNRGCSAITAAGGANARVTKTGMTRAPVFRVADVTEGAEVAQWADDNTDALAAAAESTTSHGELTDVTPYVVGDNVYLRFRYDTKDAMGMNMATIATEAASELVEDETPAELVAVSGNLCTDKKPAAINAVEGRGRTVTADVTIPQDVVEERFDTTPAAIEEANTRKNLIGSAKAGSLGFNAHAANVVAAVFLATGQDAAQVVEGANAITTVEARDDALYASVNLASLEVGTVGGGTTLPTQREALDVLGVRGGGDPAGANADALAEIIAVGALAGEINLLAALASRRLSAAHADLGR
What is the function of this protein?
Catalyzes the NADPH-dependent reductive deacylation of (S)-3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to (R)-mevalonate.  Cannot use NADH instead of NADPH.  Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
What are the official names of this protein?
3-hydroxy-3-methylglutaryl-coenzyme A reductase, HMG-CoA reductase, HMGR.
What is the protein family that this protein belongs to?
Belongs to the HMG-CoA reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMU_AGRFC
Sequence: MERSSLAVILAAGDSTRMKSSKSKVLHPVAGRPMIGHVVEAVAGAGVGAVALVVGRDADNVAAAASLKGLQVEAFLQKERKGTGHAVLAAREAIKRGFDDVIVAYGDVPLITSATLDRAREAIAAGADVAVIGFHTDRPTGYGRLLVENGELVAIREEKDATDEERKVTWCNSGLMAINGRNALDLLDRIGNSNVKGEYYLTDVVEIARSLGRRAIAIDAPEKELTGCNNRAELAFIERLWQERRRHELMVDGVSMIAPETVFLSFDTKIGQDVLIEPNVVFGPGVTIEPGAIVHAFSHLEGAHLAEGAVVGPFARLRPGANLHANAKVGNFCEVKKAEIGEGAKVNHLTYIGDAFVGAGSNIGAGAITCNYDGYNKSETRIGANSFIGSNSSLVAPVTIGERAYIASGSVITDDVPADALAFGRARQEVKPGRAVALRERAKAQKEAKKKSS
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_YERPY
Sequence: MSVIKMTDLDLAGKRVLIRADLNVPVKEGKVTSDARIRASLPTIEAALKQGAKVMVTSHLGRPTEGEYNEEFSLLPVVNYLKEKLSSPVRLAKDYLDGVEIAAGELVVLENVRFNKGEKKDDEALSKKYAALCDVYVMDAFGTAHRAQASTHGVGKFAPIACAGPLLSAELEALGKALGNPARPMVAIVGGSKVSTKLTVLGALSKIADKLIVGGGIANTFVAAQGHNVGKSLYEADLIPEAKRLLETCDIPVPTDVRVATEFSETAAATLKPANEIKDDEQILDLGDESAERLAEILKNAKTILWNGPVGVFEFPNFRKGTEIVARAIAESEAFSIAGGGDTLAAIDLFGIADQISYISTGGGAFLEFVEGKKLPAVVMLEERAKQ
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMO_PSESM
Sequence: MTAKAPRVGMISLGCPKALVDSERILTQLRMEGYEVVATYEDADVVVVNTCGFIDTAKAESLEVIGEAIKENGKVIVTGCMGVDASVIRAVHPSVLSVTGPQQYEQVVNAVHDVVPPRKDHNPLIDLVPPQGVKLTPRHYAYLKISEGCNHSCSFCIIPSMRGKLVSRPVGDVLDEAKRLVKSGVKELLVISQDTSAYGVDVKYRTGFWDGQPVKTRMTELCQALGSMGVWVRLHYVYPYPHVDELIPLMAAGKILPYLDIPFQHASPKILKLMKRPAFEDKTLARIKNWREQCPDLIIRSTFIVGFPGETEEDFQYLLDWLTEAQLDRVGCFQYSPVEGAPANLLDAAIVPDDVKQDRWDRFMAHQQAISAARLQMKIGKEIEVLIDEVDDRGAVGRCFFDAPEIDGNVFIGLEDGSTVQPGDKIMCRVTDADEYDLWAEML
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_SHIB3
Sequence: MELVLKDAQSALTVSETTFGRDFNEALVHQVVVAYAAGARQGTRAQKTRAEVTGSGKKPWRQKGTGRARSGSIKSPIWRSGGVTFAARPQDHSQKVNKKMYRGALKSILSELVRQDRLIVVEKFSVEAPKTKLLAQKLKDMALEDVLIITGELDENLFLAARNLHKVDVRDATGIDPVSLIAFDKVVMTADAVKQVEEMLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: PAPK_ECOL6
Sequence: MIKSTGALLLFAALSAGQAIASDVAFRGNLLDRPCHVSGDSLNKHVVFKTRASRDFWYPPGRSPTESFVIRLENCHATAVGKIVTLTFKGTEEAALPGHLKVTGVNAGRLGIALLDTDGSSLLKPGTSHNKGQGEKVTGNSLELPFGAYVVATPEALRTKSVVPGDYEATATFELTYR
What is the function of this protein?
Adapter that links the pilus rod to the base of the tip fibrillum.  Regulates the length of the tip fibrillum and joins it to the pilus rod.  Pili are polar filaments radiating from the surface of the bacterium to a length of 0. 5-1. 5 micrometers and numbering 100-300 per cell, and enable bacteria to colonize the epithelium of specific host organs (By similarity).
What are the official names of this protein?
Fimbrial adapter PapK.
What are the subcellular locations of this protein?
Secreted. Fimbrium.
Protein: RL2_OLEA2
Sequence: MAVRKLKPTSPGRRFQTVSSFEEITRSTPERSLTEGLTKKSGRNCYGRVTSRRRGGGHKRLYRIIDFRRDKVGVPAKVAHVEYDPNRSARIALLHYSDGEKRYILAPLGVKQGDVVVAGDSVDIKPGNAMALSRVPVGTIVHNIELYPGKGGQFCRAAGTYAQLVAKEGNYALLRMPSGEVRKVLVTCCATIGQVGNLDHEKISYGKAGRSRWLGRRPKVRGVAMNPIDHPLGGGEGRSSGGRHPVTPWGIPTKGFKTRDKKKASSKLIIKRRGQK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: CEA19_HUMAN
Sequence: MEIPMGTQGCFSKSLLLSASILVLWMLQGSQAALYIQKIPEQPQKNQDLLLSVQGVPDTFQDFNWYLGEETYGGTRLFTYIPGIQRPQRDGSAMGQRDIVGFPNGSMLLRRAQPTDSGTYQVAITINSEWTMKAKTEVQVAEKNKELPSTHLPTNAGILAATIIGSLAAGALLISCIAYLLVTRNWRGQSHRLPAPRGQGSLSILCSAVSPVPSVTPSTWMATTEKPELGPAHDAGDNNIYEVMPSPVLLVSPISDTRSINPARPLPTPPHLQAEPENHQYQQDLLNPDPAPYCQLVPTS
What are the official names of this protein?
Carcinoembryonic antigen-related cell adhesion molecule 19, Carcinoembryonic antigen-like 1.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. CEA family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: SURE_PSEF5
Sequence: MRILISNDDGVTAPGIAALHAALADYAECVVIAPDQDKSGASSSLTLDRPLHPHTLGNGFISINGTPTDCVHLGLNGLLEHDPDMVVSGINLGANLGDDVLYSGTVAAALEGRFLQRPAIAFSLVSRQVENLATAAYFARKLVQAQGLLDLPPRTVLNVNIPNLPLDHIRGIQLTRLGHRARAAAPMKVVDPRGKAGYWIAAAGDAEDGGPGTDFHAVMQGYVSVTPLQLDRTFNDAFRSLDGWLEGLR
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMM17_RAT
Sequence: MELPDPVRQRLSNLSLTMFGDSSRTGPESSEAADNEMVSSLPLQMSLYFNSYFFPLWWVSCIVMLHLKYSVLPDYYKFIVITVVILITLIEAIRLYLGCMGNLQEKVPELAGFWLLSLLLQLPLLLFLLLNEGLKNLPLEKAIHSIFTVFLTFQVISAFLTLKKMVNQLAARFHLQDFDQLSASSATGRRARQSSEEL
What is the function of this protein?
Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes.  Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity).
What are the official names of this protein?
Transmembrane protein 17.
What is the protein family that this protein belongs to?
Belongs to the TMEM17 family.
What are the subcellular locations of this protein?
Cell projection, cilium membrane; Multi-pass membrane protein. Note=Localizes to the transition zone of primary cilia.
Protein: Y04P_BPT4
Sequence: MTRNEYIKSFNSVIDDKAIPMFGQNSVLSIINQWLNSVDASIVSSTKFIHEIRKISSRVDKDVIKKTFKESRLLSYLVNRDILGNFGKEIKRTKDVVGYNWFGDVNSYHLNNKEDPENIFTRRWISNFRLFKKQILKSASKLCYGDYRQIHPLASDMIIIKEYELDKNKVSIFVNYGFFTPETNQKNINKFFSIASTITRQLETALLCMETVENIHTYPFKNICGWEGYKLVISLREVKCAYSPTSKEIYQQKCDEIVNTPKEETTLEELMECLDDSPEPIEIRPEVIALEKAYKEVLEISNKAQKEYEQAKKIWEESVNRLDRLEQALQLIK
What are the official names of this protein?
Uncharacterized 39.0 kDa protein in nrdC-mobD intergenic region.
Protein: RL29_STRPS
Sequence: MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQLEQTARLKEVKKQIARIKTVQSEAK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: RECF_CHLTB
Sequence: MRVLSLFLKDFRNYTDLRLELGPEMNSIFGLNAQGKTNLLEALYILSLGRSFRTSRLTDAIRFGASHFFIEAVFSHKEVFHTLSIQVDKKGKKILFDGAPITKLSELVGLFPVILFSIKDIAIIEGSPSERRRFLDLLLAQASDKYTEHISLYHKALDQRNASIKAQNQKAISAWNSPLIAYGSLVAFLRNECTKKLNTIFQTLWDNTLKETLSLRYESSLITEESPTLNDIASNYYEQLRIANTKDLDLGYTMVGPHRDELLLTINDLPVAKFSSEGQKHSLLAVLRFAECVYLQEEFCIHPLLCMDDIHACLDQQRLDQLLQLSNSLGQVVTTSTICPDHRSTTSCIFHVTQAQVSLVAPQSL
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CUTC_KLEP3
Sequence: MAVLEVCCYSMACAREAERCGADRIELCAAPQEGGLTPSYGVLVSVREAITLPVHPIVRPRGGDFCYTEQEFAAMLSDIRMVRELGFPGLVTGVLNADGQVDIPRMKKIMAAAGPLAVTFHRAFDLCADPRQAWKTLGELGVKRILTSGQQSSAEKGISLITELIAAGDTPIIMAGAGVRAANLPLLLQAGVKEVHSSAGQWLPSDMRFRHPGVSMSADPDADEYRRYAVNGEAVAEMKGIISAWRS
What are the official names of this protein?
PF03932 family protein CutC.
What is the protein family that this protein belongs to?
Belongs to the CutC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_PELPD
Sequence: MSNTLKITLVKSLIGTPKQQRNVVAGLGLKKLNTTVVRSDTPEIRGMINKISHMLHIA
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: SPH17_ARATH
Sequence: MKNLSIFMFVFSLCMFGHVSRARIRIANELKFKKNLWMRCYSKDDVLGPHIIPIGGHFLDYFGTNFWGTTRFMCTLRQGPNYIHYQSFTAFKLFSMEDHGGLWDWRAREDGIYLKKEGNKFIKNPVNMHKVYDWIN
What are the official names of this protein?
S-protein homolog 17.
What is the protein family that this protein belongs to?
Belongs to the plant self-incompatibility (S1) protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSBA3_SYNP6
Sequence: MTSILREQRRDNVWDRFCEWVTSTDNRIYVGWFGVLMIPTLLTATICFIVAFIAAPPVDIDGIREPVAGSLMYGNNIISGAVVPSSNAIGLHFYPIWEAASLDEWLYNGGPYQLVVFHFLLGISCYMGRQWELSYRLGMRPWICVAYSAPLSAAFAVFLIYPIGQGSFSDGMPLGISGTFNFMFVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLVRETTETESQNYGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLGAWPVVGIWFTSMGISTMAFNLNGFNFNQSVLDSQGKVINTWADVLNRANLGMEVMHERNAHNFPLDLAAGEATPVALTAPSIHG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1 3, PSII D1 protein 3, Photosystem II Q(B) protein 3.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: OPSD2_ANGAN
Sequence: MNGTEGPNFYVPMSNVTGVVRSPFEYPQYYLAEPWAYSALAAYMFFLIIAGFPINFLTLYVTIEHKKLRTPLNYILLNLAVADLFMVFGGFTTTMYTSMHGYFVFGPTGCNIEGFFATLGGEIALWCLVVLAVERWMVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLFGWSRYIPEGMQCSCGMDHYAPNPETYNESFVIYMFICHFTIPLTVISFCYGRLVCTVKEATAQQQESETTQRAEREVTRMVIIMVISFLVCWVPYASVAWYIFTHQGSSFGPIFMTIPAFFAKSSSLYNPLIYICMNKQSRNCMITTLCCGKNPFEEEEGASTTASKTEASSVSSVSPA
What is the function of this protein?
Visual pigments such as rhodopsin and porphyropsin are light-absorbing molecules that mediate vision.  Rhodopsin consists of an apoprotein, opsin, covalently linked to 11-cis-retinal.  This receptor is coupled to the activation of phospholipase C.  Porphyropsin consists of opsin covalently linked to 11-cis 3,4-didehydroretinal.
What are the official names of this protein?
Rhodopsin, freshwater form.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: LPXH_VIBVY
Sequence: MTTLFISDLHLTPSRTDITECFVQFMRNEAVNAEALYVLGDLFEFWIGDEDCTPFAERIRNEFKALTTSGVPVYFIQGNRDFLLGQRFCRETGITLLDDVCTIDLYGEKVVILHGDTLCIDDLKYQEFRKTVHQPWLQWIFKRIPWFIKKRIVAKVQSGVRDDKQHKSLEIMDVNQQEVAQVMSQFCVKLMIHGHTHRPNIHHFEHDNLPLTRIVLGDWYSQGSVLKVTADGYSLEQRPFFTE
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RISB_HELPH
Sequence: MQIIEGKLQLQGNERVAILTSRFNHIITDRLKEGAMDCFKRHGGDEDLLDIVLVPGAYELPLILDKLLESGKYDGVCVLGAIIRGGTPHFDYVSAEATKGIASAMLKYSMPVSFGVLTTDNIEQAIERAGSKAGNKGFEAMSTLIELLSLCQTLKG
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: NHAB_PECCP
Sequence: MTGMPLHRALLKNFLGYAPDWYKLTIFCFLLVNPLLFYFVSPFWAGWLLVVEFIFTLGMALKCYPLQPGGLLALQAMLIGMTSPQQVWHEVTGNIEVLMLLVFMVAGIYFMKQLLLFVFTKLLLRIHSKALLSLAFCGAAAFLSAFLDALTVIAVVISVAIGFYGIYHRFASQQGGNEADISDDSALSSEEHRHTLEQFRAFLRSLLMHAGVGTALGGVMTMVGEPQNLIIAKSAGWDFVSFFLHMSPVTVPVFICGILTCVLVERFKLFGYGVNLPDNVRRVLEDYDRDMTEKRTPQDKVRLLVQAVIGVWLIVALAFHLAEVGLIGLSVIIMATAFCGVTEEHAIGKAFQDAMPFTALLTVFFAIVAVIIDQQLFSPIIRYVLQSSESSQLTQFYLFNGLLSSISDNVFVGSVYINEARSAFENGHISLSQFELLAVAINTGTNLPSVATPNGQAAFLFLLTSSLAPLIRLSYGRMVIMALPYTIVMTLVGLLCVEFTLVPFTDFLMNNHWISLPNLTLSGSHS
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaB, Sodium/proton antiporter NhaB.
What is the protein family that this protein belongs to?
Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RADA_TREPA
Sequence: MAKKTERAFSCVGCGYVHPKWLGRCPECGEWNSFEETPSLSSGDVRAVKKASSSPVQAFPLCAVRAQDAQRISCGIAEFDRVLGGGAVRRSAIMIGGEPGIGKSTLLLQIAAACGKSVLYVSGEESPGQIRGRADRLNIPIQNIELLCATRVEDVERVLNTRCPTFVIVDSIQTVFSPEAGAIPMTINQLKYCANELIAWVKERDSVLFFTAHVTKDGNIAGPKVVEHMVDTVISFERNEEDIRFLRALKNRFGSVDELGIFTMGENGLSAVQDTAGFFISTRQGMFPVGSATVPVCEGSRVFMVEIQALTVPAKSSVTRVFSDRIDSARVSRVAAVIEKRVGLKFSDQDIYVNVAGGIRLYEPAVDVALAMALYSARQNTPVKTNAAFIGEVSLSGEIRPVRRLKTRLKTAYGLGFSTIYVPIGVEHDTPPPYTLRVVGTLAQTIAEIFSKAKA
What is the function of this protein?
DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks.  Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster.  Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB.  Does not have RecA's homology-searching function.
What are the official names of this protein?
DNA repair protein RadA, Branch migration protein RadA.
What is the protein family that this protein belongs to?
Belongs to the RecA family. RadA subfamily.
Protein: DAPA_GLUDA
Sequence: METTMFKGSITALITPMNDDGSLDFSGFGRFVDWQVTEGSSGVVPVGTTGESPTLTHEEHARIVEYTVQVVAGRIPVIAGAGSNSTAEAVGMARHAKSVGADGVLVVAPYYNKPTQEGLYRHFMTVADATDLPLIIYNIPGRSVVDISVETMARMAQHARIVGVKDATANLLRPLQVRRAIRHKPFTQLSGEDGTVVSFLAAGGEGCISVTSNIAPRLCAELHRAWQDGRVADAMAIQDRLSAVHDALFCESNPGPVKYAASLLGLAGETCRLPLAPLAEDSRMRVREALTGAGLLN
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPX_MYCBT
Sequence: MTAEGSGSSTAAVASHDPSHTRPSRREAPDRNLAMELVRVTEAGAMAAGRWVGRGDKEGGDGAAVDAMRELVNSVSMRGVVVIGEGEKDHAPMLYNGEEVGNGDGPECDFAVDPIDGTTLMSKGMTNAISVLAVADRGTMFDPSAVFYMNKIAVGPDAAHVLDITAPISENIRAVAKVKDLSVRDMTVCILDRPRHAQLIHDVRATGARIRLITDGDVAGAISACRPHSGTDLLAGIGGTPEGIIAAAAIRCMGGAIQAQLAPRDDAERRKALEAGYDLNQVLTTEDLVSGENVFFCATGVTDGDLLKGVRYYPGGCTTHSIVMRSKSGTVRMIEAYHRLSKLNEYSAIDFTGDSSAVYPLP
What is the function of this protein?
Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate.
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 2, FBPase class 2, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 2.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLNE_CITK8
Sequence: MKPLSSPLQQHWQTVVERLPEILAEATLSVQAKSVLTFSDFVQDSVIAHPEWLTELESAPPQADEWRHYAAWLQDALAQVTDEAALMRELRVFRRRIMVRIAWAQALSLVEEENILQQLSHLAETLIVAARDWLYDACCREWGTPCNHDGVPQPLLILGMGKLGGGELNFSSDIDLIFAWPEHGSTRGGRRELDNAQFFTRMGQRLIKVLDQPTMDGFVYRVDMRLRPFGDSGPLVLSFAALEDYYQEQGRDWERYAMVKARIMGAADSAYVDELRAMLRPFVFRRYIDFSVIQSLRNMKGMIAREVRRRGLKDNIKLGAGGIREIEFIVQVFQLIRGGREPSLQSRSLLPTLSAIDALHLLPENDAGQLRAAYLFLRRLENLLQSINDEQTQTLPGDELNRARLAWGMRTDDWSQLTDILAAHMANVRRVFNELIGDDETDTQEDTLSEHWRELWQDALQEDDTTPVLAHLSDDDRGRVLALIADFRKELDKRTIGPRGRQVLDHLMPHLLSDVCSREDASVPLSRITPLLVGIVTRTTYLELLSEFPGALKHLISLCAASPMVASQLARYPLLLDELLDPNTLYQPTATDAYRDELRQYLLRVPEDDEEQQLEALRQFKQTQLLRIAAADIAGTLPVMKVSDHLTWLAEAIIDAVVQQAWGQMVARYGQPTHLAERTGRGFAVVGYGKLGGWELGYSSDLDLIFLHDCPMDVMTDGEREIDGRQFYLRLAQRIMHLFSTRTSSGILYEVDARLRPSGAAGMLVTSAEAFADYQKNEAWTWEHQALVRARVVYGDPQLTSQFDAVRRDIMTLAREGKTLQTEVREMREKMRAHLGNKHRDRFDIKADEGGITDIEFITQYLVLRYAHEKPKLTRWSDNVRILELLAQNDIMDEQEAHALTLAYTTLRDELHHLALQELPGHVAQECFSKERALVRASWQKWLVAG
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia.  When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity.  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity.  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.