PharMolix/UniProtQA huggingface dataset:
Protein: AERD_PLAAG
Sequence: MLKFSMEFCYPQPDVKTLIVGTLGPKETSSEQTLNYLITQWQAEQISVTSHLFDTFTELKEALLQDRVDLALVPHAYERVNDFYMEPSLKLGFVFTYPTPIYGLAKRKNEELVWENCTLVTHPAPFPLLPYLLPGYPHQKNIKVEFVNSTSAAAIQVKQGLADLAITNENALKENDLEFIAEYGKIEMSWSIFHKKGTVHRE
What is the function of this protein?
In vivo, involved in the biosynthesis of 2-carboxy-6-hydroxyoctahydroindole (Choi) present in the nonribosomal glycopeptides aeruginoside 126A and B.  AerD is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate.  AerD catalyzes the protonation at C8 followed by decarboxylation to produce the dihydro-4-hydroxyphenylpyruvate regioisomer A258 (H2HPP A258)(3-(4-hydroxycyclohexa- 1,5-dienyl)-2-oxopropanoic acid), which is able to undergo a nonenzymatic isomerization to produce dihydro-4-hydroxyphenylpyruvate regioisomer A295 (H2HPP A295)(3-(4-hydroxycyclohex-2-enylidene)-2-oxopropanoic acid).
What are the official names of this protein?
Prephenate decarboxylase, Aeruginosin biosynthesis protein AerD.
What is the protein family that this protein belongs to?
Belongs to the prephenate decarboxylase family.
Protein: NRDIB_BACSU
Sequence: MTYESKTGNVKRFVKALQQEFDVEAIEITDDTIINQEFIHITYTIGFGEVPERTLSFINKNKNKIRGVAVSGNKVWGDNYGLAGDKLSAKFHTPLLLKFELSGTKQDLQKIIQEVQLIDKHNTKLDQAQ
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
SPbeta prophage-derived protein NrdI, BnrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: YOR72_YEAST
Sequence: MLTKVVFLFFWSRSDSTKKLAACNHATLAHYILTPALYSDACAIYSDVYSITIIVVATVVRNPARCSLRARKFCRLFSSFFQFHYLKELFYFIRKPDDKFSSFI
What are the official names of this protein?
Uncharacterized protein YOR072W.
Protein: POXH_PENO1
Sequence: MSTTTTMRAWTYMQSGLPSQTIVLDDEAPSPSAAELGPDELLIAVNYVAMNSGFTTLMRSLPPQPYSLPHIYNRQKRLGVPEFEFSGRILAVGSAIPSTRPDLQPSTLVLGCCAAKRVFIEGKGALAERVIAPAAQLIPLRPLSTVTTQDDESPGPDPAAPPISLLEASGLSACGCTAVQVLDLTKLVAGDKLFVNGGSTSVGMLIIQVARQVLGQTGTIIASGTDATLIRSVGADDVIDYTAQRPLHEFLRTHHAGRPFDAIIDCVGVAELYTHCEPYLAPGKLFINLGAMTAKPTFWGLLSFVWNQHMAPLWPVVLGGVPRSYQFYSARPNRETLGRVMRLVERGELRMVVDSVWEMRDAKMAYKRMESKRAKGKIIVRVQEE
What is the function of this protein?
Trans-enoyl reductase; part of the gene cluster that mediates the biosynthesis of oxaleimides, cytotoxic compounds containing an unusual disubstituted succinimide moiety (PubMed:28365998).  The first step of the pathway is provided by the HR-PKS poxF that serves in a new mode of collaborative biosynthesis with the PKS-NRPS poxE, by providing the olefin containing amino acid substrate via the synthesis of an ACP-bound dec-4-enoate (PubMed:28365998).  The cytochrome P450 monooxygenase poxM-catalyzed oxidation at the alpha-position creates the enzyme-bound 2-hydroxydec-4-enoyl-ACP thioester, which may be prone to spontaneous hydrolysis to yield 2-hydroxydec-4-enoic acid due to increased electrophilicity of the carbonyl (PubMed:28365998).  2-hydroxydec-4-enoic acid can then be further oxidized by poxM to yield the alpha-ketoacid 2-oxodec-4-enoicacid, which is reductively aminated by the aminotransferase poxL to yield (S,E)-2-aminodec-4-enoic acid (PubMed:28365998).  The Hybrid PKS-NRPS synthetase poxE then performs condensation between the octaketide product of its PKS modules and the amino group of (S,E)-2-aminodec-4-enoic acid which is activated and incorporated by the adenylation domain (PubMed:28365998).  The resulting aminoacyl product can be cyclized by the Diels-Alderase PoxQ and reductively released by the reductive (R) domain of poxE to yield an aldehyde intermediate (PubMed:28365998) (Probable).  The released aldehyde is then substrate for a Knoevenagel condensation by the hydrolyase poxO followed by an oxidation at the 5-position of the pyrrolidone ring (PubMed:28365998).  The presence of the olefin from the amino acid building block allows for migration of the substituted allyl group to occur (PubMed:28365998).  This allylic transposition reaction takes place in a conjugate addition, semipinacol-like fashion to yield a succinimide intermediate (PubMed:28365998).  Iterative two-electron oxidations of the C7 methyl of the succinimide intermediate to the carboxylic acid can be catalyzed by one of two remaining cytochrome P450 monooxygenasess poxC or poxD to yield oxaleimide A (PubMed:28365998).  Subsequent oxidation yields the maleimide scaffold oxaleimide I (PubMed:28365998).  Both oxaleimide A and oxaleimide I can undergo oxidative modifications in the decalin ring to yield the series of products oxaleimides B to H (PubMed:28365998).
What are the official names of this protein?
Trans-enoyl reductase poxH, Oxaleimides biosynthesis cluster protein H.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: TI17B_HUMAN
Sequence: MEEYAREPCPWRIVDDCGGAFTMGVIGGGVFQAIKGFRNAPVGIRHRLRGSANAVRIRAPQIGGSFAVWGGLFSTIDCGLVRLRGKEDPWNSITSGALTGAVLAARSGPLAMVGSAMMGGILLALIEGVGILLTRYTAQQFRNAPPFLEDPSQLPPKDGTPAPGYPSYQQYH
What is the function of this protein?
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit Tim17-B.
What is the protein family that this protein belongs to?
Belongs to the Tim17/Tim22/Tim23 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TILS_BACAN
Sequence: MKDTFVEKVDDFVRQHDVLKERSTIVVGVSGGPDSLALLYYLLEKRAAKQFEIVVAHVDHMFRGDESHEDLQFVQDLCKGLGVICETIRINVSQYQKQYGMNAQVAARECRYAFLERIMKKYDARYVALGHHGDDQVETILMRLVRGSTPKGYAGIAVKRPFHNGYLIRPLLGVTKEEIVNYCNELKIIPRIDPSNKKEVYTRNRLRKYVLPHLKEENPQVHEKFQKFSMQMQEDEAYLQELAFEKMNKVITKKSDKQISLSIPTFESMSMPLQRRGIQLILNYLYEYKIPSSLSSIHIDKVIEFFKRTQPSGSLDFPGDLKIVRAYEECSFGFKQEIVSPFLQDLSVPGTITLSNGDKLVTEVSEDIPSDMNETVFVAKYNDISYPIRIRSRENGDRMSIQGMNGTKKIKAIFIEAKVPREKREEWPVVCDASGNIIWLPLLKRSAFAISKETAKKDKYMIIHYKSKESSGRIMK
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPR1_PLAF7
Sequence: MKLTYYYYAFCIIKVIASLRLDSYKKQNVFFLKAFFKNVINIKKERKKNLVNSFFYVGRRNKIPIKYSNNEFYNIHNENYDNTKYYNNNNNTNDYDKKDNNVGKRKYSRKNMLYMNSSEKDNFLNENILKKKSSEKEIEQSLTPLNMDWVKVMNLIYSSNDIDATTLAFNAAMSAVEKKGCLSTMLDLIGTMKSKNIKPDLVSYKLVLSLCDKYHLVDTAEILFEEMIESDKINPNYEIYAIMISCYAKTGNGYKAIELFEKLRNDPFVEEMRSLNITNTNDNKENSNDLQTSIIHNNMEDNNNNNNNNDNNIYDDKFKHISNKIKNVENCSGKIQYSEYANVIYACNISNLYEQGIKYFEELLKSGKYMPSIFVFENIFDLLSKNGDYEKSLEYYNNLKNDPNFKKNINVNILNNLLKALSIHNKINVAEDIWNNEFDELLLTPNNLSYQILLKIYSHIDNYEKAFKLFKEMQVNKLLNNKNILPFIYTIESTKNCGIYNYAIYVLRVAKLLNFKANDLLMLYNNTMISCINSKKYDVIISLYAELINMQQKDTSFQININTLTFVLLAFKELNMKQDFINLKNIIIQRNYKLPPLCSKIFSETENY
What is the function of this protein?
Binds to apicoplast RNA transcripts, preferentially to the motif UUAU, and protects RNA transcripts from degradation by ribonuclease.
What are the official names of this protein?
Pentatricopeptide repeat-containing protein 1, apicoplast, PfPPR1.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
What are the subcellular locations of this protein?
Plastid, apicoplast.
Protein: LRGB_STAES
Sequence: MIEHLGINTPYFGILVSLIPFVIATYFYKKTNGFFLLAPLFVSMVAGIAFLKLTGISYENYKIGGDIINFFLEPATICFAIPLYRKREVLKRYWLQIFGGIAVGTIIALLLIYLVAITFQFGNQIIASMLPQAATTAIALPVSDGIGGVKELTSLAVILNAVVISALGAKIVKLFKISNPIARGLALGTSGHTLGVAAAKELGETEESMGSIAVVIVGVIVVAVVPILAPILL
What is the function of this protein?
Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and/or CidB.  The LrgAB and CidAB proteins may affect the proton motive force of the membrane.  May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses.
What are the official names of this protein?
Antiholin-like protein LrgB.
What is the protein family that this protein belongs to?
Belongs to the CidB/LrgB family. LrgB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ERO1_CAEEL
Sequence: MREPLLQLIVLSLIIIVVNTQFESGRLCFCKGFEAVEPCDCSKPQTIDKLNNHRIYEKVQKLLKKDFFRFYKVNMDKTCPFWADDRQCGTNQCGIAFCDDEVPAGLRRRNAVNMEAAAVKEEEDDDAEKCADAGNNIDPMDRTLHDDEKRQLDAMDHHDDGLEDKFCEIEDDESDGMHYVDLSKNPERYTGYAGKSPQRVWKSIYEENCFKPDPKFDKNFLTNPSNFGMCLEKRVFYRLISGLHSAITISIAAYNYKPPPPSLGQFGSQMGTWFRNTEMFAGRFGTKWSWEGPQRLRNVYFIYLLELRALLKAAPYLQNELFYTGNDVEDAETRKAVEDLLEEIRAYPNHFDESEMFTGVESHARALREEFRSHFVNISRIMDCVECDKCRLWGKVQTHGMGTALKILFSDLPHSHYKQDSSKFQLTRNEVVALLQSFGRYSSSILEVDNFREDMYPGESVMNTAADGPPRKSNKIDL
What is the function of this protein?
Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum.  Efficiently reoxidizes pdi-1, the enzyme catalyzing protein disulfide formation, in order to allow pdi-1 to sustain additional rounds of disulfide formation.  Following pdi reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell (By similarity).
What are the official names of this protein?
Endoplasmic reticulum oxidoreductin-1.
What is the protein family that this protein belongs to?
Belongs to the EROs family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side.
Protein: SFSA_SHESM
Sequence: MHFSPALKPGKLLKRYKRFLADVQLEDGTEITLHCPNTGSMRNCLFPGETVWFSTSNNPKRKYAHTWELMATPTGGLIGIHSGNANALVEEALNKGIITELTGYDSLSREVKYGDENSRIDILLESAQKPACYIEVKSCTLLEDGQGYFPDAVSLRGQKHLRELMHMASLGHRAVLLFVVQHTDIHSVAPAAHIDPEYANLLKKAILSGVEVLAYRCEISPDEIHLAQSCPVRV
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: FOLD_META1
Sequence: MPVILDGKRLSEALQAKIAMAFSAYRGPKPILGILQVGNKEDSNIYVAHKLKVAESLGFLTKLVKMPENSTQDEIIGTLRNAAAEVTGIIVQLPLVSNRIENLQEILDNIPIEKDIDGLSSYNLASNYNCKDNFLSATPKGIILLLKHYNINFRSTVIALVGQSNIVGKPLAKYLSNFKNNTIKTYVKDTPKDDLHEAKIVIVATGVYQSVTADQLANGTVLIDVGIHRQGKTIHGDLDFASCFKKASYITPVPGGVGPLTVVALMFNLIKALILQNPNLDHEFLSLKEFINI
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: RL11_HERA2
Sequence: MAKKVTAVVKLQLPAGKATPAPPVGPALGATGINIMAFCKDYNEKTSAQVGTIIPVEITVYSDRSFTYILKTPPAADLLRKAAGIQRGSGKTGTQGAGSITRAQLRQLAETKMPDLNANDIEAAEKIIAGTARSMGIAIKD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: PUR7_MYCBO
Sequence: MRPALSDYQHVASGKVREIYRVDDEHLLLVASDRISAYDYVLDSTIPDKGRVLTAMSAFFFGLVDAPNHLAGPPDDPRIPDEVLGRALVVRRLEMLPVECVARGYLTGSGLLDYQATGKVCGIALPPGLVEASRFATPLFTPATKAALGDHDENISFDRVVEMVGALRANQLRDRTLQTYVQAADHALTRGIIIADTKFEFGIDRHGNLLLADEIFTPDSSRYWPADDYRAGVVQTSFDKQFVRSWLTGSESGWDRGSDRPPPPLPEHIVEATRARYINAYERISELKFDDWIGPGA
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: AROE_VEREI
Sequence: MRQTADLYCVLGNPIAHSRSPAIHARFAELTGERIRYERRLLPIDGFARGLRDFAAQGGRGCSVTVPFKTEALRCATACSERAQLAGAANTLSLHADGSISADNTDGLGLVADITRNAGIALAGCDVLLVGAGGAAAGVLGPLLHAGVRHITVANRTLAKAQALVQSHSALAALRKTQLKACGLQAPLADFDIIINASASSLAGADVPVPASVLRPASLAYDMMYGPAAQGFLDWARRHGARPRDGLGMLVEQAAEAFWLWRGLRPPSAQVLAELQEAAAKPASGADR
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: HEM6_PSEPG
Sequence: MTSRTEAVKAYLLDLQDRICSALETEDGGARFVEDAWVREAGGGGRTRVIGDGKVIEKGGVNFSHVFGAGLPPSASAHRPELAGRGFEALGVSLVIHPHNPHVPTSHANVRFFIAEKEGEEAVWWFGGGFDLTPYYGNEEDCIHWHRVAEQACAPFGADVYPRYKAWCDRYFHLKHRGEPRGIGGLFFDDLNEWDFDTCFAFIRAIGDAYVNAYLPIVQRRKDTPYTPQQREFQEYRRGRYVEFNLVYDRGTLFGLQSGGRTESILMSLPPQVRWGYDWKAAPGSEEARLTEYFLQDRDWLGQ
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSH_SYNY3
Sequence: MSHTLTKLDLPTLQTELENATAQQIITWAAQTFGPGLVMSTSFGIQAAVMLHLVTSIVPNIPVIWIDTGYLPLETYQFADQLTGRLQLNLKVYQSPLSPARMEALYGKLWQQKDVESLNRYDQIRKVEPMQRALKELEAIAWLTGLRRDQTRHRQNLKPVDLQGNQYKVLPILDWNSKMVYEYLTAHDLPYHPFFDQGYVSVGDWHSSRPLMAHDEDERDTRFHGLKQECGLHLPLSPEAGQSLDSSAL
What is the function of this protein?
Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
What are the official names of this protein?
Phosphoadenosine 5'-phosphosulfate reductase, PAPS reductase, 3'-phosphoadenylylsulfate reductase, PAPS reductase, thioredoxin dependent, PAPS sulfotransferase, PAdoPS reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS3_CHLCH
Sequence: MNNSLESTKQLLDVVKFDSNGLVPAIVQDVESGKVLMMAWMNRESLAMTLEKKVACYWSRSRKELWLKGETSGNMQQVHDVLIDCDGDTLLLKVSQKGGACHVGYHSCFYRKATENGSLEICDTLMFNPEEVYGKKS
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUC_LARHH
Sequence: MAAQTLYDKLWESHVVRTDPDGTSLLYIDRHLVHEVTSPQAFEGLKLAGRKPWRVHSIVATADHNTPTDNWDLGIAGIKDPVSRLQVETLDANVRETGALAYFPFMDRNQGIVHVVGPEQGATLPGMTVVCGDSHTSTHGAFAALAHGIGTSEVEHVMATQCLTAKKSKAMLVRVEGELQAGVTAKDIALAVIGRIGTAGGTGYAIEFAGSAIRGLSMEGRMTLCNMAIEAGARSGLVAVDQVTLDYVKGRPFAPTAEQWEAAVACWRELKSDEGAVFDAVVELDATTIAPQVTWGTSPEMVVAITDRVPDPAAEADPVKREGMQRALAYMGLTAGTPMAEIAVDKVFVGSCTNSRIEDLREAAAVVRGRRKADSVRLAMVVPGSGNVKAEAEAEGLDKIFVAAGFEWREPGCSMCLAMNADRLEPGERCASTSNRNFEGRQGQGGRTHLVSPAMAAAAAIAGHFVDIRKGY
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: RAN2_SOLLC
Sequence: MALPNQQTVDYPSFKLVIVGDGGTGKTTFVKRHLTGEFEKKYEPTIGVEVHPLDFFTNCGKIRFYCWDTAGQEKFGGLRDGYYIHGQCAIIMFDVTARLTYKNVPTWHRDLCRVCENIPIVLCGNKVDVKNRQVKAKQVTFHRKKNLQYYEISAKSNYNFEKPFLYLARKLAGDGNLHFVESPALAPPEVQIDLAAQALHEQELQAALNQPLPDDDDEAFE
What is the function of this protein?
GTP-binding protein involved in nucleocytoplasmic transport.  Required for the import of protein into the nucleus and also for RNA export.  Involved in chromatin condensation and control of cell cycle (By similarity).
What are the official names of this protein?
GTP-binding nuclear protein Ran2, Ras-related nuclear protein 2.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ran family.
What are the subcellular locations of this protein?
Nucleus.
Protein: XNI_SODGM
Sequence: MSVHLLIVDALNLIRRIHAVQGASCLAACGHALSQLILHCTPSHAVAVFDDDERHESWRHQQLPQYKSGRAPIPEDLQALMPAIRAEFNRQSVTCWHASGFEADDIAATLAIKVAAGGHRVTLVSTDKGYCQLLSPSIQIRDYFQKRWLDMPFVMRHFGVQPQQLTDFWGLAGVSSSKIPGVAGIGPKSAAQLISEAGTLEALYQRLAQLPEKWRHRLEHDRDLAFLCRRIVTLDTAVTLQGNLQQLRLR
What is the function of this protein?
Has flap endonuclease activity.  During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.
What are the official names of this protein?
Flap endonuclease Xni, FEN.
What is the protein family that this protein belongs to?
Belongs to the Xni family.
Protein: MINE_ECOK1
Sequence: MALLDFFLSRKKNTANIAKERLQIIVAERRRSDAEPHYLPQLRKDILEVICKYVQIDPEMVTVQLEQKDGDISILELNVTLPEAEELK
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: MTRA_MYCPA
Sequence: MRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLPGMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLRRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP
What is the function of this protein?
Member of the two-component regulatory system MtrA/MtrB.
What are the official names of this protein?
DNA-binding response regulator MtrA.
Protein: KGUA_YERPN
Sequence: MVQGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSISHTTRAKRPGENHGEHYFFVSEKEFCQMIDDDAFLEHAKVFENYYGTSRLAIEQVLATGVDVFLDIDWQGAQQIRAKMPTARSIFILPPSKTELDRRLRGRGQDSEEVIAKRMEQAVAEMAHYAEYDYLIVNDDFNLALSDLKTIIRAERLRLGRQKQRHDALISKLLAD
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NANM_YERPA
Sequence: MTQLYPQYKKQLTTKIVLFSALSLLMMASLPNTYAEQYPDVPVPFKNGTGGKVENSLYVGLGSAGVSWFRLDTDKTGAGWQKVANFPGQPREQAVTVVLAGKLYVFGGVGKTNANDTQVRALDDAYRFDPQTNQWQQLATRAPRGLVGTVATTLDGSQAVLLGGVNKAIFDGYFTDLASAGSDEVRKSAVINAYFNQAPADYFYNRDVLIYDPQKNQWKSGGLLPFLGTAGSAISRMDNRLILINGEIKPGLRTAAVWQGLMQGNVLEWQPQPDLIGAETGSAQEGLAGAFSGISHKTVLVAGGANFPGAWKQFNRGHLYAHQGLEKQWHQQVYALVDNQWRIAGKLPQPLGYGVSIQGPDKVILIGGETTGGTATSAVTQLSWQGGKLHIE
What is the function of this protein?
Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers.  Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer.  In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses.
What are the official names of this protein?
N-acetylneuraminate epimerase, N-acetylneuraminate mutarotase, Neu5Ac mutarotase, Sialic acid epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanM family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PSAJ_BUXMI
Sequence: MRDLKTYLSVAPVLSTLWFGSLAGLLIEINRLFPDALTFPFFSF
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX, PSI-J.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CHO2_NEUCR
Sequence: MSSSAADPFAARLNSDVRQRHPTASATSKNVEGTSQQKQQQQQQQSEANAAASRVKKTYGKTPDGTVFVVPTTHDMVTQLLDPREPKNLSDVAVLAIIALHFLAAYYLPWGVKRPLFAAIFMFWRLAYNVGIGYLLTIQSKYKLLVTWAKRWKLFENPATGKNPRPWLYNLLKKELETKIPQDYKFEEAPIEYNTWLTFRRVVDLILMCDFISYCLFAIVCAHKPDGEGLFMCFARWAAGITLVGFNLWVKLDAHRVVKDYAWYWGDFFYLIEQELTFDGVFELAPHPMYSIGYAGYYGISMMAASYDVLFISIIAHAAQFAFLVIVENPHIEKTYNPPQPRVRCESEAGSQLQEFASEYSVPSTTGRHDNTPLPVHNLIGLKNLDFFRITDVAIVLLCAYLAVVTMVTPNTRFYQALFVLHALAWRLWYSAGLGVILTMQSEEKMFTRHFLKYGESVGEAWRQWKGIYHLSNCLCHASFIAASYKMYEFPADWTYGWALLKHVVGLSLIALQVWTATSIYESLGEFGWFYGDFFFDSKRQLTYTSIYRFLNNPERVFGTAGLWGAALITWSRAIFLMALAGHFLTLAFLAYVEKPHMQKVYGRNLRDDAGVTKFIKRSLPPPVTEWQQSIDKVLDETKHFIDEFVDAARSRLATGSSTIVKDTSALFNKYPARLTLSKISPDLAGYDPKHYGLSLAGTRVVGTNEKATGKESPNARVLKDVKTQAFEYGAPIRVKWTAPANHSKKDWVGLYMVTDNRSREVTEVPSLGRWVPTNPGEYDTTTDQGILVWDQPVEKKSEDTDLVEGEMVFEGDKLWWTQGVFEFRYHHGGGHHVMSISEPFEIQIPKFDDEHMGVDISGEVGERAVEAALLPVIRNCLDRDPDIAPSNAEERFGGHVERDGKYARRVVYAIRHMFGIDFAPAVVLADGNVRRLAWRICHAKEVLAPFSMSHTNGRTTPVDSKFSE
What is the function of this protein?
Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME).
What are the official names of this protein?
Phosphatidylethanolamine N-methyltransferase, PE methyltransferase, PEAMT, PEMT, Cholineless.
What is the protein family that this protein belongs to?
Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi- pass membrane protein.
Protein: RS10_STRPI
Sequence: MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPTERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RL31_SALG2
Sequence: MKKGIHPNYVEITATCSCGNVIKTHSTVGHDLNLDVCGKCHPFFTGKQRVVDTGGRVERFNKRFSIPGSK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: RIMO_RHOBA
Sequence: MMQLPILPQNNVTVATPGTDPMIDPETGKPRGRYAVVSLGCPKNLVDTEQMLGRLDADGYRMVDSVDGADFVVVNTCGFIDSARDESMAAIDEMLALKRDGKLRNVVVTGCLAERQQDKLLQARPDIDALVGVFGRNDIVSVVDELYSGLQEQRTIFKPAAVNPLSDAMRSAVTPRHFAYLKISEGCDRLCTFCAIPKMRGKHFSKPIEQIIDEAKRLGDSGVREVVIVAQDTTYYGMDRYGEPRLNQLLKELDKIESIDWIRLMYFYPMYIDDALIDTLASARRIVPYIDMPLQHASDKMLKRMARKTTRSLQTDIVQKLRSRIDSLVMRTTMITGFPGETEEDFVELMDFVQESRFENLGVFTYSIEEDTPAARLPNRVDPEVAARRRDDLMELQQQIAFDWNDSRVGGTEEVLIDAEMPEQDNVFIGRTRSEAPDVDGLIYVSQVDPDSPVEVGQIRPCEIVASQGYDLVAAAT
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.