PharMolix/UniProtQA huggingface dataset:
Protein: SPEE_LEPIC
Sequence: MQTALYISVLIISSCGLVYELLAGTIASYLLGETVTQFSLIIGTYLFSMGVGSWLSKYLEKDLIPKFLEIELAIGLVGGFSSAILYLSFGQIRYFQIPLFLLVILIGILVGLEIPVLLRILKKELQFKELVSRVLSLDYVGALLASILFPIFFAPKLGLMRTGFIFGILNVGVALWGTWVLPLRQSKIIILRAQSVVVLTLLILGFSYSDLITYYSEESLYTDEIILSKQTQYQRIIVTRWKNEIRLFLNGHLQFSSRDEYRYHETLVHPALLAHPTPKKVLVLGGGDGLAVREILKHKNVESVTLVDLDSAITNLFSEHGILKKLNEESLKNSKVTVINTDAFLWLEESDQIFDVVLIDFPDPSNFSLGKLYTTAFFHTLKRRMNETSVLEIQSTSPLFARSSYWCIERTIASLGFYTLPLHVYVPSFGEWGFVLAGQRPIQFKKDFPKDLKFLNIQELESIQTFPQDMSRVPVEINRLDNQALVRYYDREWNRILD
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: QUEC_LEGPH
Sequence: MKKAVVLLSGGLDSTTCLALAKSQGFACYALSFSYGQRHSAELCAATRIAKHMGAADHKIVTLDIALFGGSALTDASIEVPEFKESPEIPVTYVPARNTIFLAMALGYAESIGARDIFIGASSVDYSHYPDCRPEFIESFQSLANLATKAGIEGDRFTINAPLQYLSKVQTIQLGTELGVDYGLTVSCYQANEAGEACGQCDSCTFRKRGFKSAGVDDPTRYQKCVHI
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: MNHF2_STAES
Sequence: MIEMFTQIFIISALVIFGMALLVCLVRLIKGPTTADRVVSFDASSAVVMSIVGVMSVIFNSVSYLDSIMLIAIISFVSSVSISRFIGEGRVFNGNHKRHR
What are the official names of this protein?
Putative antiporter subunit mnhF2, Mrp complex subunit F2, Putative NADH-ubiquinone oxidoreductase subunit mnhF2.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSAJ_ANTAG
Sequence: MQDVKTYLSTAPVLATLWFGFLAGLLIEINRSFSDALVLPFF
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX, PSI-J.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: NADA_HALS3
Sequence: MDTSSFETDLSLFKYDDLEALPDEYRELTPTARTERIEAARAELGDDVVVLGHNYQRREIVEHADFVGDSYQLSKEAANADADYVIFGGVTFMAESADIITDDSQSVILPSMEASCPMAGMAEALQVDAAWADITAAAPDETIIPITYMNSYADLKAFCAEQGGLVCTSSNAHRAFEWAFERGDKVLFLPDKHLGENTAHRLGMADATVEWDPWAAEGKTAEEVADADIVLWDGYCQVHERFTPEHVAEVRADHEDANVVVHPECRREVVEAADVVGSTATITETVADADPGETWAIGTEIHLANHLQRWHPEVNVVPLCGDACMDCNAMRQIDPNYLAWVLEELVEGRERNVIEVDSEEAELAQVGLDRMLEL
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUN_MYTED
Sequence: NQKCSGNPRRYNGKSCASTTNYHDSHKGACGCGPASGDAQFGWNAGSFVAAASQMYFDSGNKGWCGQHCGQCIKLTTTGGYVPGQGGPVREGLSKTFMITNLCPNIYPNQDWCNQGSQYGGHNKYGYELHLDLENGRSQVTGMGWNNPETTWEVVNCDSEHNHDHRTPSNSMYGQCQCAHQ
What is the function of this protein?
Active towards the soluble carboxymethylcellulose (CMC).  Possesses expansin activity too.
What are the official names of this protein?
Endoglucanase, CMCase, Cellulase, Endo-1,4-beta-glucanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 45 (cellulase K) family.
Protein: UBIA_SHIB3
Sequence: MEWSLTQNKLLAFHRLMRTDKPIGALLLLWPTLWALWVATPGVPQLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRPLPSGAVTEKEARALFVVLVLISFLLVLTLNTMTILLSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAVSESVPLSCWLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGILQIGVLALMAIIGELNGLGWGYYWSILVAGALFVYQQKLIANREREACFKAFMNNNYVGLVLFLGLAMSYWHF
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NADD_YERPN
Sequence: MPIKSSDHSLYALFGGTFDPIHYGHLKPVEALAQQVGLQHIILLPNHVPPHRPQPEANAQQRLKMVELAVAGNPLFSVDSRELLRDSPSFTIETLEALRKERGAEQPLAFIIGQDSLLSLHKWHRWQALLDVCHLLVCARPGYSQSLETPELQQWLESHKVMDPQALSQRPHGAIYLADTPLLDISATDIRRRRHNGESCDDLLPQAVQRYIELQGLYRG
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: NDKA2_BOVIN
Sequence: MANSERTFIAIKPDGVQRGLMGEIIKRFEQKGFRLVAMKFMRASEDLLKEHYIDLKDRPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIALWFRPEELVNYKSCAQNWIYE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities.  Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression.  Required for neural development including neural patterning and cell fate determination.
What are the official names of this protein?
Nucleoside diphosphate kinase A 2, NDK A 2, NDP kinase A 2, Nucleoside diphosphate kinase NBR-B, NDK NBR-B.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Nucleus.
Protein: NU4M_WHEAT
Sequence: MLEHFCECYFDLSGLILCPVLGSIILLFIPNSSIRLIRLIGLCVSLITFLYSLVLWIQFDPSTAKFQFVESLRWLPYENIHLYMGIDGLSLFFVILTTFLIPICILVGWSGMRSFGKEYIIAFLICEFLMIAVFCMLDLLLFYVFFESVLIPMFIIIGVWGSRQRKIKAAYQFFLYTLLGSVFMLLAILLILLQTGTTDLQILLTTEFSERRQILLWIAFFASFAVKVPMVPVHIWLPEAHVEAPTAGSVILAGILLKLGTYGFLRFSIPMFPEATLCFTPFIYTLSAIAIIYTSLTTLRQIDLKKIIAYSSVAHMNLVTIGMFSLNIQGIGGSILLMLSHGLVSSALFLCVGVLYDRHKTRLVRYYGGLVSTMPNFSTIFFFFTLANMSLPGTSSFIGEFLILVGAFQRNSLVATLRALGMILGAAYSLWLYNRVVSGNLKPDFLYKFSDLNGREVFIFLPFLVGVVWMGVYPKVFLDCMHTSVSNLVQHGKFH
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: EX7L_HELP2
Sequence: MDVLSVSEINAQIKALLEATFLQVRVQGEVSNLTIHKVSGHAYFSLKDSQSVIRCVLFKGNANRLKFALKEGQEMVVFGGISVYVPRGDYQINCFEIEPKEIGSLTLALEQLKEKLRLKGYFDEANKLPKPHFPKRVAVITSQNSAAWADMKKIASKRWPMCELVCINTLMQGEGCVQSVVESIAYADSLHDTKNAFDAIVVARGGGSMEDLYSFNDEKIADALYLAKTFSMSAIGHESDFLLSDLVADLRASTPSNAMEILLPNSDEWLQKLDGFNVKLHRSFKILLHQKKAYLEHLADFLKRLSFENKHHLNALKLEKLKIALENKTLEFLRFKKTLLEKISTQTLTSPFLQTKTERLNALENALKLAHANLKLPQFGAFLSKNNQAIELEALKRGDKIELSNEKARASAEILSVDRV
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIG1_KLUMA
Sequence: MSSEVVPLQKKGRKKAGAGVVVDGEKDGSRPYMCPICHRGFHRLEHQTRHIRTHTGERPHACDFPGCAKRFSRSDELTRHRRIHDSDKPKGKRGRKKKSETIAREKELELQRQRQQQQLQQQQQQQLQQQQHQVLPAEIKISAPMASSMMEVTQAINQRYQDTHNLSLSYNSGSNSNASSGSNSNSSLNQVFSITSQPARDLAAKPMFQLGSDESEETSNTTTLHSVHSQQQNNGSVELLLNAARFESEKSTTLLNNNTPSFKFIDRPPLTSSLSSPALSLVSQSPVAGAGPGFGPANGNGNGAANNNGLLLPRPTSRPKLSALSTLKRMTPLSQVSEPQQPAASLPHLQQVSSNGFLDTNGHAASVARNKSWTNLGVMPSPSESGSSALVSRFSSSASLNKLMDPSSRTSSAVSIATLMNEDKLQSQDDLSVVDEFGRSRKKSKTSTPIRRPSSNMGFGTGPASHAMEFCNELQSRLKSVDQYSDRSAGDEKDYYFQSRSSSSVCTPINSPPSERLVSSTSNNKTIKLPSLRSLDILPREQH
What is the function of this protein?
Involved in glucose repression of glucose metabolism genes.
What are the official names of this protein?
Regulatory protein MIG1.
What is the protein family that this protein belongs to?
Belongs to the creA/MIG C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1630_STAA1
Sequence: MMDNKDYKKFYLIREDVLPESVVKTLKIKDALKSDPTLSIYDAVKQFDLSRSAFYKYRETIFPVDDKMLDHREFTLILYVTDIVGMLARVLDVISKLELSVLTIHQSIPMEEKATITLSLNAKSKETSVEDVIGALRNLDYVSKVELISMSM
What are the official names of this protein?
UPF0735 ACT domain-containing protein SAHV_1630.
What is the protein family that this protein belongs to?
Belongs to the UPF0735 family.
Protein: YHEN_MANHA
Sequence: MEYQFTHSIHGVVAKCSMDHEAFARWLNAEITENPSQLAPIFAEIEKCRAAFPNHYECVFEGREYSLYFDYDEVMAKANNLDAAFDDEEMEEGFQFYNEESIAFCGLDDFEKFLKAYQHFVQTYH
What are the official names of this protein?
UPF0231 protein in hemN 3'region, orf1.
What is the protein family that this protein belongs to?
Belongs to the UPF0231 family.
Protein: RS4_COXB2
Sequence: MARYLGPKCRLSRREKTDLQLKSGIRAIDSKCNIERIPGMHWQRRGRTTDYGVQLRMKQMIKRYYDVLEKQFANYYKQADRLKGSTGDNLLKLLESRLDNVVYRMGFAATRAEARQLISHKAILVNGEVVNIPSYQVKPGDIIEVRSRAKGQLRIKGALELAQQRAPISWIEVDTKKMTGTFKEQPDVAELPAEFKVNLVVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RL9_MYCLB
Sequence: MKLILTADVDHLGSVGDTVEVKDGYGRNFLLPHGLAIVASRGAQRQADEIRRARETKAMRDREHANEIKVAIEALGSVSLPMKTVADSGKLFGSVTAGDVVAAIKKAGGPNLDKRIVRLPKTHIKAVGTHPVSVHLHPEVDVVVLLDVVAAR
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: CSKP_HUMAN
Sequence: MADDDVLFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYAYKIHLPETVEQLRKFNARRKLKGAVLAAVSSHKFNSFYGDPPEELPDFSEDPTSSGLLAAERAVSQVLDSLEEIHALTDCSEKDLDFLHSVFQDQHLHTLLDLYDKINTKSSPQIRNPPSDAVQRAKEVLEEISCYPENNDAKELKRILTQPHFMALLQTHDVVAHEVYSDEALRVTPPPTSPYLNGDSPESANGDMDMENVTRVRLVQFQKNTDEPMGITLKMNELNHCIVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRTQSSSCERDSPSTSRQSPANGHSSTNNSVSDLPSTTQPKGRQIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSPELQEWRVACIAMEKTKQEQQASCTWFGKKKKQYKDKYLAKHNAVFDQLDLVTYEEVVKLPAFKRKTLVLLGAHGVGRRHIKNTLITKHPDRFAYPIPHTTRPPKKDEENGKNYYFVSHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQALKVLRTAEFAPFVVFIAAPTITPGLNEDESLQRLQKESDILQRTYAHYFDLTIINNEIDETIRHLEEAVELVCTAPQWVPVSWVY
What is the function of this protein?
Multidomain scaffolding Mg(2+)-independent protein kinase that catalyzes the phosphotransfer from ATP to proteins such as NRXN1, and plays a role in synaptic transmembrane protein anchoring and ion channel trafficking (PubMed:18423203).  Contributes to neural development and regulation of gene expression via interaction with the transcription factor TBR1.  Binds to cell-surface proteins, including amyloid precursor protein, neurexins and syndecans.  May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4. 1.  Component of the LIN-10-LIN-2-LIN-7 complex, which associates with the motor protein KIF17 to transport vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules (By similarity).
What are the official names of this protein?
Peripheral plasma membrane protein CASK, hCASK, Calcium/calmodulin-dependent serine protein kinase, Protein lin-2 homolog.
What is the protein family that this protein belongs to?
Belongs to the MAGUK family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: CRYAA_PERPO
Sequence: MDVTIQHPWFKRPLGPFYPSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQSLFRTVLDSGVSEVRSDRDKFVIFLDVKHFSPEDLTVKVQEDFVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSVSADGMLTFSGPKVQSGLDAGHSERAIPVSREEKPSSAPSS
What is the function of this protein?
Contributes to the transparency and refractive index of the lens.  Acts as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions.  Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA.
What are the official names of this protein?
Alpha-crystallin A chain.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
Protein: MRAY_STRGG
Sequence: MRQILFAGAIGLFLTLVGTPLLIKLLARKGYGQFIRDDGPRTHGSKKGTPTMGGIAFILATIVAYLLAKVITGEDIRYSGLLVLFLMAGMGLVGFLDDYIKIVKQRSLGLRAKAKMAGQLIVGIAFAVLSLQFPNSMNYTPASTRLSFVEDFGWSIGPVLFCVWALFMILAMSNGVNLTDGLDGLATGASVMVFGAYTFIGLWQFQESCANADNLTNPSACYEVRDPLDLAVVAAALMGACFGFLWWNTSPAKIFMGDTGSLALGGALAGLAILSRTEFLLAILGGLFVMITMSVVIQVGSFKMTGKRVFRMAPLQHHFELKGWSEVLVVVRFWIIQGMCVIVGLGLFYAGWAAKK
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SNX41_SCHPO
Sequence: MDFFEDNNPFSGSDNRSASSAVNVEPKVEPSQHQGSSSVKENAISQPNESFQSRNMFFQKDVDSVVDSALDPNGIVITGAMKAESGSHIVYIIKLQDSEIHHRYSEFASLRVQLSRLYPTCLVPPLPDKHKIMDYLINVTKNQRMSRMLEERKRLLQLFLRRVAQHPILGLSEVFRKFLSRHVSWKEVLHSPPISCLPKDLLKAPPADPSSKENAELYKELPIPSKTLVPRDNYDDVGKNFLMLEDTLQQYSIVAQEESNLFNQIVLSNSKYCLAHSTLGAMFNALSLSESGKLLTALEKVGQANDHTCLASIDFMHNFVIAVIEPLQELSKDAKNMRHIFIFRKMKFIQQVMVEELLTRKKSFLHLLERRERHAARLQQAIGEVDGDVILNRESEATLGVNNAQTSRSTIPEEDPLFNDEESKEPSVPLMGTDQPLENYHDGNGEQTEECLRDLRHNQSQDFETVSQDTSLTSVTVLPRTIRDVFDRIRFVLNGLTDNNVEVSRHNNIGRTAESVTHLTDMLLITTKDVAFVTDRVNFEFQRYQDTHRQDLNRILNRLTDSHIDWANRNLRIWNSVQESLKTYVS
What is the function of this protein?
May be required for cytoplasm to vacuole transport (Cvt) and pexophagy (By similarity).  Has a role in meiosis.
What are the official names of this protein?
Sorting nexin-41, Meiotically up-regulated gene 186 protein.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Cytoplasm. Endosome membrane; Peripheral membrane protein. Endomembrane system; Peripheral membrane protein. Note=Endosome and other perivacuolar punctate structures.
Protein: TIG_CITK8
Sequence: MQVSVETTQGLGRRVTITIAADSIETAVKSELVNVAKKVRIDGFRKGKVPMNVVAQRYGASVRQDVLGDLMSRNFVDAIIKEKINPAGAPNYVPGEYKLGEDFTYAVEFEVYPEVELTGLESIEVEKPVVEVTDADVDVMLDTLRKQQATWKDKDGAADAEDRVTIDFTGSVDGEEFEGGKASDFVLAMGQGRMIPGFEDGIKGHKAGEEFTIDVTFPEEYHAENLKGKAAKFAINLKKVEERELPELTEEFIKRFGVEDGSVAGLRTEVRKNMERELKGAVRNRVKSQAIEGLVKANDIDVPSALIDSEVDVLRRQAAQRFGGNEKQALELPRELFEEQAKRRVVVGLLLGEVIRTQELKADEERVKGLIEEMASAYEDPKEVIEFYSKNKELMDNMRNVALEEQAVEAVLAKAKVTEKATSFNELMNQQA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: RLR70_PLAVT
Sequence: MRGAYYIITALLVVASSQELRGSGHQLQIYDHDVVKAVKAVMKTLPNRFLRESRDVHDDLANEERSFYSILADIINKGMDTMPRAAEGVELMPNAAEGVEKMPRAAEGVETIPHAAEGVENMPHVPDEGLSKALTGAKTALNKLWGPFSATTPIGDASHDVSSREQIDFEIGSWSIDLRGFKPIAVHDQHKDMIQRVYTKFGQLCGNNLNPTAEETSLIWTMFDSRIVPSSSKDDRLKLIWQARQNVRSDMRSISSSKKWRYRWQGSPDSLTLDVLNSLLNMHYQRWVRMYDIFKQERPDLIDAPSNSKHTLGGNKDSSSATTLHKHSKGLSSRPFEPLNAVMMSHGDRFVSTQRSKRTFGSNADTVSLPLKQPKMRSSKALMPLSATLGDYSVPPLKSRLNFGGASSAFVPYTHPKAHTSKSLAPASTTLTLKDSELELSLGGIYDKNTG
What is the function of this protein?
Secreted effector that completely suppresses the host cell death induced by cell death-inducing proteins.
What are the official names of this protein?
Secreted RxLR effector protein 70.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host nucleus.
Protein: CSTN3_BOVIN
Sequence: MTPLLFPLLLASLLPSSSCNKANKHKPWIEAEYQGIVMENDNTVLLNPPLFALDKDAPLRYAGEICGFRLHGSGVPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYDRILRVEAIDGDCSPQYSQICYYEILTPNTPFLIDNDGNIENTEKLQYSGEKLYKFTVTAYDCGKKRAADDAEVEIQVKPTCKPSWQGWNKRIEYAPGAGSLALFPGIRLETCDEPLWNIQATIELQTSHVAKGCDRDNYSERALRKLCGAAPGEVDLLPMPGPNANWTAGLSVHYSQDSSLIYWFNGTQAVQVPLGGAAGLGSGPPDSLSDHFTLSFWMKHGVTPNKGKKEEETIVCNTVQNEDGFSHYSLTVHGCRIAFLYWPLLESARPVKFLWKLEQVCDDEWHHYALNLEFPTVTLYADGISFDPALIHDNGLIHPPRREPALMIGACWAEEKNKEKEKGGDNSTDATAGDPLPIHHYFHGYLAGFSVRSGRLESREVIECLYACREGLDYRDFESLGKGMKVHVNPSQSLLTLEGDDVETFNHALQHVAYMNTLRFATPGVRPLRLTTAVKCFSEESCVSIPEVEGYVVVLQPDAPQILLSGTAHFARPAVDFEGPEGVPLFPDLQITCSISHQVEAKKDESWQGTVTDTRMSDEIVHNLDGCEISLVGDDLDPERESLLLDMASLQQRGLELTNTSAYLTIAGVESITVYEEILRQARYRLRHGAALYARKFRLSCSEMNGRYSSNEFIVEVSVLHSVNRVAHPSHMLSSQQFLHRGHQPPPEMAGHSLASSHRNSMVPSAATLIIVVCVGFLVLMVVLGLVRIHSLHRRVSGASGPPGASSDPKDPDLFWDDSALTIIVNPMESYQSRQVCVAGAAGGQQDDEDSSDSEAADSPSSDERRIIETPPHRY
What is the function of this protein?
Postsynaptic adhesion molecule that binds to presynaptic neurexins to mediate both excitatory and inhibitory synapse formation.  Promotes synapse development by acting as a cell adhesion molecule at the postsynaptic membrane, which associates with both neurexin-alpha and neurexin-beta proteins at the presynaptic membrane (By similarity).  Regulates the balance between excitatory and inhibitory synapses by inhibiting formation of excitatory parallel-fiber synapses and promoting formation of inhibitory synapses in the same neuron (By similarity).  May also be involved in ascorbate (vitamin C) uptake via its interaction with SLC23A2/SVCT2.  Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation (By similarity).
What are the official names of this protein?
Calsyntenin-3.
What is the protein family that this protein belongs to?
Belongs to the calsyntenin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane. Golgi apparatus membrane. Postsynapse. Cell projection, dendrite. Note=Most prominent in the postsynaptic specializations of asymmetric (type I) synapses with both axodendritic and axospinous localization.
Protein: NDK_METFK
Sequence: MAVERTLSIIKPDAVAKNVIGKIYTRFEDAGLKIIASKMVQLSQADAEGFYAVHKERPFFNDLVKFMISGPVVVQVLEGENAVLKHRELMGATDPKKAEPGTIRADFADSIDANAVHGSDSLENAAVEIAYFFAQSNIYSR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TES_RHIFE
Sequence: MDLAVKVKKMGLGHEQGFGAPCLKCKEKCEGFELHFWRKICRNCKCGQEEHDVLLSNEEDRKVGKLFEDTKYTTLIAKLKSDGIPMYKRNVMILTNPVAAKKNVSINTVTYEWAPPVQNQALARHYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPKEVKEMEQFVKKYKSEALGVGDVKLPREMDAQGPPRIDSPGGDRSTAAAVGAMDGKSAEHRRTQYSCYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCEELLVDMIYFWKNGKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDNILAGEIYVMVDDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNGFSWHAAAECFLCSCCSKCLLGQKFMPVEGMVFCSVECKKMMS
What is the function of this protein?
Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton.  Plays a role in the regulation of cell proliferation.  May act as a tumor suppressor (By similarity).
What are the official names of this protein?
Testin.
What is the protein family that this protein belongs to?
Belongs to the prickle / espinas / testin family.
What are the subcellular locations of this protein?
Cytoplasm. Cell junction, focal adhesion. Note=Detected along actin stress fibers.
Protein: TRPD_LACPL
Sequence: MIETAIAQLTNQENLDFTMSQQVITEIMKGQATDAQIGSFLTALAIKKATIDEIAGAATAMRSQALPFKVKRPTLEIVGTGGDRSNSFNISTTTALVVAAAGVPVTKHGNRAASSKSGAADVLEALGIKIDLTPAQSLALLERTNFAFMYAREYHQAMRFVAPARQQIKIPTIFNILGPLANPAHAEMQLLGVYRQALMAPLAEVLTRLGVKHAMVVHSRDGLDEISAAAPTDVIVINHGQQVTRILTPEQFGLTRCDHAALIGGSAQVNAAITRAVLTGEPGAPRDVVLMNAAAALHIAKPQLDLAAAFELAQQTIDQGAAAAKLAQLIQSSQAVMAS
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: HIS7_LEPIC
Sequence: MTDKLIGFYDPVRMKAERKTSETEIKLEMNLRGTGQYQFDTEIPFFEHMLSHISKHGLIDLNLWLRGDIEIDCHHSVEDTAILMGTTIHKQLGDKAGIFRYGHFTLTMDEVLTTVAVDLGGRYFFKYTGPELTGKFGIYDAELSLEFLQKLALNAKMNLHVVVHYGDNKHHVHESIFKALGKALRMAIAQDSAAAGAIPSTKGVLE
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.