PharMolix/UniProtQA huggingface dataset:
Protein: PLSL_HUMAN
Sequence: MARGSVSDEEMMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLDQDGRISFDEFIKIFHGLKSTDVAKTFRKAINKKEGICAIGGTSEQSSVGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMINLSVPDTIDERTINKKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIELSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKAYYHLLEQVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAERLGCRQFVTATDVVRGNPKLNLAFIANLFNRYPALHKPENQDIDWGALEGETREERTFRNWMNSLGVNPRVNHLYSDLSDALVIFQLYEKIKVPVDWNRVNKPPYPKLGGNMKKLENCNYAVELGKNQAKFSLVGIGGQDLNEGNRTLTLALIWQLMRRYTLNILEEIGGGQKVNDDIIVNWVNETLREAKKSSSISSFKDPKISTSLPVLDLIDAIQPGSINYDLLKTENLNDDEKLNNAKYAISMARKIGARVYALPEDLVEVNPKMVMTVFACLMGKGMKRV
What is the function of this protein?
Actin-binding protein (PubMed:16636079, PubMed:17294403, PubMed:28493397).  Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28 (PubMed:17294403).  Modulates the cell surface expression of IL2RA/CD25 and CD69 (PubMed:17294403).
What are the official names of this protein?
Plastin-2, L-plastin, LC64P, Lymphocyte cytosolic protein 1, LCP-1.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell junction. Cell projection. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Relocalizes to the immunological synapse between peripheral blood T-lymphocytes and antibody-presenting cells in response to costimulation through TCR/CD3 and CD2 or CD28 (PubMed:17294403). Associated with the actin cytoskeleton at membrane ruffles. Relocalizes to actin-rich cell projections upon serine phosphorylation (PubMed:16636079).
Protein: EF1B_WHEAT
Sequence: MAVTFSDLHTADGLKALEAHLAGKTYISGDGITKDDVKVFAAVPLKPSAEFPNAARWYDTVAAAVSSRFPGQASGVSASSAPAAAAPAASKDEDDDDDMDLFGDETEEDKKAAAEREAAKPAKKKESGKSSVLMDIKPWDDETDMKKLEEAVRSVQMEGLTWGASKLMPVGYGIKKLQIMLTIIDDLASTPIEEVLCEAPINEYVQSCDIVAFNKI
What is the function of this protein?
EF-1-beta and EF-1-beta' stimulate the exchange of GDP bound to EF-1-alpha to GTP.
What are the official names of this protein?
Elongation factor 1-beta, EF-1-beta, Elongation factor 1-beta', EF-1-beta', Elongation factor 1B-alpha 2, eEF-1B alpha 2.
What is the protein family that this protein belongs to?
Belongs to the EF-1-beta/EF-1-delta family.
Protein: GLGB_CANGA
Sequence: MSLTKIPENVQGAVSIDPWLEPFADVLSERRYLADKWLYDIKHATPDGSEQSLVDFARNAYKTYGLHANQQTKEIVYREWAPNAQRAFLVGEFNNWNEESHEMKHKDEFGVFSITLAPLENGDFAIPHDSKIKVMFVLPDGSKVYRIPAWITRATQPSKETAQKYGPTYEGRFWNPPNSYQFKHQRPKFNLANDSIKIYEAHIGISSPEPKVASYKEFTQNVLPRIKHLGYDAIQLMAIMEHAYYASFGYQVTNFFAISSRYGTPEDLKELIDTAHSMGILVLLDVIHSHASKNSEDGLNMFDGSDHQYFHSLTSGRGEHPLWDSRLFNYGSFEVQRFLLANLAYYIDVYQFDGFRFDGVTSMLYLHHGVGAGGAFSGDYNEYLSRDRSGVDHEALAYLMLANDLVHDLLPESAVTIAEDVSGYPTLCLPRTAGGGGFDYRLAMALPDMWIKLLKTKQDDDWDMGHIVHTLTNRRHGEKVVAYCESHDQALVGDKTLAFWLMDAAMYTDMTVLKEPTLVIDRGIALHKMIRLITHSLGGEAYLNFEGNEFGHPEWLDFPRVGNNDSYHYARRQFNLVDDDLLRYRHLNEFDAAMQNCESKHQWLNTPQAYVSLKHEVDKVIAFERNGHLFVFNFHPTQSFTDYRIGVDVAGTYKIVLNTDRAEFGGHNRIDEAQEFFTTDLEWNNRRNFIQVYIPSRTAIVLTRQM
What are the official names of this protein?
1,4-alpha-glucan-branching enzyme, Glycogen-branching enzyme.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: PSD12_HUMAN
Sequence: MADGGSERADGRIVKMEVDYSATVDQRLPECAKLAKEGRLQEVIETLLSLEKQTRTASDMVSTSRILVAVVKMCYEAKEWDLLNENIMLLSKRRSQLKQAVAKMVQQCCTYVEEITDLPIKLRLIDTLRMVTEGKIYVEIERARLTKTLATIKEQNGDVKEAASILQELQVETYGSMEKKERVEFILEQMRLCLAVKDYIRTQIISKKINTKFFQEENTEKLKLKYYNLMIQLDQHEGSYLSICKHYRAIYDTPCIQAESEKWQQALKSVVLYVILAPFDNEQSDLVHRISGDKKLEEIPKYKDLLKLFTTMELMRWSTLVEDYGMELRKGSLESPATDVFGSTEEGEKRWKDLKNRVVEHNIRIMAKYYTRITMKRMAQLLDLSVDESEAFLSNLVVNKTIFAKVDRLAGIINFQRPKDPNNLLNDWSQKLNSLMSLVNKTTHLIAKEEMIHNLQ
What is the function of this protein?
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.  This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required.  Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.
What are the official names of this protein?
26S proteasome non-ATPase regulatory subunit 12, 26S proteasome regulatory subunit RPN5, 26S proteasome regulatory subunit p55.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit p55 family.
Protein: PG36_MYCBO
Sequence: MSFVIASPEALLAAATDLAAIRSTIRAANAAAAVPTTGALAPAADEVSAGIAALFGAQAQSYQAVSAQAAAFHDRFVQLLNAGGGSYASAEIANAQQNLLNAVNAPTQTLLGRPLVGDGADGASGPVGQPGGDGGILWGNGGNGGDSTSPGVAGGAGGSAGLIGNGGRGGNGAPGGAGGNGGLGGLLLGNGGAGGVGGTGDNGVGDLGAGGGGGDGGLGGRAGLIGHGGAGGNGGDGGHGGSGKAGGSGGSGGFGQFGGAGGLLYGNGGAAGSGGNGGDAGTGVSSDGFAGLGGSGGRGGDAGLIGVGGGGGNGGDPGLGARLFQVGSRGGDGGVGGWLYGDGGGGGDGGNGGLPFIGSTNAGNGGSARLIGNGGAGGSGGSGAPGSVSSGGVGGAGNPGGSGGNGGVWYGNGGAGGAAGQGGPGMNTTSPGGPGGVGGHGGTAILFGDGGAGGAGAAGGPGTPDGAAGPGGSGGTGGLLFGVPGPSGPDG
What are the official names of this protein?
Uncharacterized PE-PGRS family protein PE_PGRS36.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PE family. PGRS subfamily.
Protein: LPTD_VIBCH
Sequence: MSCFSRTFLAASISAALFAPQIQAEASVDDNRAQLPNGEQCLVNQPEPTNPGQQPINVEADKLEAINGQKATYSGNVVVVQGKKRIAADNVTLHQQENVVVAEGNVQFSDGEIKTHSTKATNHLNTDEMTLENTRYQFLCEPGRGEAVYVSKTGKAVYEIEDGSITSCPDGDNAWRMRASSIDVDQNEEIATFYNPRLEVQNVPVFYLPYLTVPIGDTRKTGFLYPTASYGSRNGYSFEVPIYWNLAPQYDLETTFNYMQKRGTQLNSVFRYLTDFGAGQIKSEYLADDQLHTELGDRWAFQYEHNGIFQQAWKFEIDYSKVSDINYFSDLDSGVGNREDGQLIQEGRATYRSDNWDSALLVRDFQLLTKDTTSTNLPYRLMPQLSYNYYAPETMKYLDLDLVSHVSRFETDARGKPSATRVHIEPGLKIPFSNTWGNWTTEARVLGTYYQQDLDKTTDAKLEESVTRVIPEIRSVAGIVLERDTVLLDDYTQTLEPKIQYLYVPEKYQDNIGLYDSTLLQTDYYGLFRSRKYSGVDRIESANQVSYGASTRFFDSNYKERLNIAFGQIFYLDSKLNPSNKNPDSTSDKTSYSAWAVEMDFNFADYLFYHGGIQYDIDSQAVQLGNSTLEYRVASGYIQANYRYVAKDYIRNTVGDSITNIDDITRDGISQAGILAGYQLSRKWSASGQYYYDLTTDEALEWLANLTYTSDCWYVGFTYSNQLKSWNGNFVTDPYATPIYENNFSFNIGIIGFGTSIGAGSSMTGVDSAGNSLGYGRPFFLNN
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: Y1946_CLOBM
Sequence: MDNNVDTITLTDEEGKKTEFEVITKLDIEDKEYVVVVPKDEEVDEAIALRIDNNDNGEEVLVPVEEDEEFNMVAEAYELLFSEEQ
What are the official names of this protein?
UPF0473 protein CLK_1946.
What is the protein family that this protein belongs to?
Belongs to the UPF0473 family.
Protein: PYRE_STRAW
Sequence: MDDVRGALLQQIKDKAVVHGKVTLSSGLEADYYVDLRRITLDGEAAPLVGQVLLDLTADLDFDAVGGLTMGADPVAAAMLHAAAARGRRLDAFVVRKAAKAHGLQRRVEGPEIKGRRVLVVEDTSTTGGSPLTAVEAVREAGAEVVGVATIVDRATGAAEKIEAGAGVPYRFAYDKDELGLD
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: LTAA_STAAW
Sequence: MQDSSLNNYANHKNFILMLIILFLMEFARGMYILSYINFLPTVTSIAVAITSLAFSIHFIADASTNFVIGFLLKKFGTKIVLTTGFILAFTSLFLVIWFPASPFVIIFSAMMLGIAVSPIWVIMLSSVEEDKRGKQMGYVYFSWLLGLLVGMVFMNLLIKVHPTRFAFMMSLVVLIAWILYYFVDVKLTNYNTRPVKAQLRQIVDVTKRHLLLFPGILLQGAAIAALVPILPTYATKVINVSTIEYTVAIIIGGIGCAVSMLFLSKLIDNRSRNFMYGVILSGFILYMILIFTLSMIVNIHIVWIIALAIGLMYGILLPAWNTFMARFIKSDEQEETWGVFNSIQGFGSMIGPLFGGLITQFTNNLNNTFYFSALIFLVLAVFYGSYFIANREKAK
What is the function of this protein?
Proton-coupled antiporter flippase that catalyzes the translocation, from the inner to the outer leaflet of the cell membrane, of the lipid-linked disaccharide (anchor-LLD) that anchors lipoteichoic acids (LTA) to the cell membrane.
What are the official names of this protein?
Proton-coupled antiporter flippase LtaA, Lipoteichoic acid protein A.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. LtaA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: WT1_ALLMI
Sequence: QGYSTVAFDGPPSYGHAPSHHAAQFSNHSFKHEDPIAQQTSLGDQQYSVPPPVYGCHTPTDSCTGSQALLLRTPYNSDNLYQMTSQLECMTWNQMNLGSTLKGHATGYENENHTAPMLYSCGAQYRIHTHGVFRGIQDVRRVPGVAPTIVRSASETNEKRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGKTSEKPFSCRWPSCQKKFARSDELVRHHNMHQRNMTKLQLAL
What is the function of this protein?
Transcription factor that plays an important role in cellular development and cell survival.  Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'.  Regulates the expression of numerous target genes.  Plays an essential role for development of the urogenital system.  It has a tumor suppressor as well as an oncogenic role in tumor formation.  Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors.  Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing.
What are the official names of this protein?
Wilms tumor protein homolog.
What is the protein family that this protein belongs to?
Belongs to the EGR C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
[Isoform 1]: Nucleus speckle. SUBCELLULAR LOCATION: [Isoform 2]: Nucleus, nucleoplasm. SUBCELLULAR LOCATION: Nucleus. Cytoplasm. Nucleus speckle. Note=Shuttles between nucleus and cytoplasm.
Protein: HIS2_MYCMM
Sequence: MKQSLAVKTFEDLFAELGDRARTRPPGSATVAALDAGVHTLGKKVLEEAGEVWLAAEHESNEALAEEISQLLYWTQVLMISRGVSLDEVYRKL
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURB_RICCN
Sequence: MLILPIVKGEYKKDYNLKHLTWFKVGGNAEIFFKPLDSEDLKSFLIQNKQKLPIKTFGAGSNIIIRDGGIEGVVIKLGQNFSNIEFVDNHLIVGSSCLNYNLAKFCQANAISGFEFLVGIPGTIGGGVAMNAGAYGSEFKDIVVQIEAIDFAGNFLTFTNEEIGFKYRSNNLPKNLIILKAVFKINKGDSENILLRMNEIKNARSSTQPIKERTGGSTFANPEGRKSWELIDKAGLRGYRIGGASMSEFHCNFMINNGDATAKDLEDLGDFVRQKVCEDSGVKLEWEIKRIGRHP
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_LACH4
Sequence: MSRTPIIAGNWKLHMNPEQTAEFVDAVKDKLPDPSKVESLICAPAVDLDALRKAAKGSNLHIGAENCYFEDEGAYTGETSPKVLKEMGIDYVIIGHSERRGYFHETDEDINKKAKAIFANGLKPIICCGESLETREANKQEDWVVGQIKAALDGLTAEQVSNLVIAYEPIWAIGTGKTASSDQAEEMCKTIRETVKDLYNEETAENVRIQYGGSVKPANVKELMSKPDIDGGLVGGASLKPESYLELVNYQD
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUON_SHIFL
Sequence: MTITPQNLIALLPLLIVGLTVVVVMLSIAWRRNHFLNATLSVIGLNAALVSLWFVGQAGAMDVTPLMRVDGFAMLYTGLVLLASLATCTFAYPWLEGYNDNKDEFYLLVLIAALGGILLANANHLASLFLGIELISLPLFGLVGYAFRQKRSLEASIKYTILSAAASSFLLFGMALVYAQSGDLSFVALGKNLGDGMLNEPLLLAGFGMMIVGLGFKLSLVPFHLWTPDVYQGAPAPVSTFLATASKIAIFGVVMRLFLYAPVGDSEAIRVVLAIIAFASIIFGNLMALSQTNIKRLLGYSSISHLGYLLVALIALQTGEMSMEAVGVYLAGYLFSSLGAFGVVSLMSSPYRGPDADSLFSYRGLFWHRPILAAVMTVMMLSLAGIPMTLGFIGKFYVLAVGVQAHLWWLVGAVVVGSAIGLYYYLRVAVSLYLHAPEQPGRDAPSNWQYSAGGIVVLISALLVLVLGVWPQPLISIVRLAMPLM
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SPLR_NPVOP
Sequence: MYKLCAVLFALAVPAVRPHGYLSTPVARQYKCFADGNFYWPDNGDGVPDEACRNAYKKVFHRYRAVGAPPGEAAAAAQYMFQQYAEYAAVAGPNYRDLELVKREVLPHTLCGAAANDRHALFGDKSGMDEPFHNWRPDVLYVNRYQRAHSFNVHFCPTAVHEPSYFEVYVTKFTWDRRSPVTWNELEYIGGNGSGLVPNPGDAFCASGQLYSIPVSVPYRPGPFVMYVRWQRIDPVGEGFYNCADLVFGTENDECRYARAAKAVRDQLRQQNLCNDCVEAGPQESCAPTRPQRRAHNYLRRGGAHDQQADGASVRETIDEL
What is the function of this protein?
Component of the virus occlusion bodies, which are large proteinaceous structures (polyhedra), that protect the virus from the outside environment for extended periods until they are ingested by insect larvae.
What are the official names of this protein?
Spheroidin-like protein, 37 kDa glycoprotein, Spindolin-like protein.
What are the subcellular locations of this protein?
Host membrane. Note=Occlusion body. Associated with the periphery of occlusion bodies and with the internal membranes of infected cells.
Protein: RUVB_EHRRG
Sequence: MFMKDILQSSECIEDQQNISMRPNLLDEFIGQSSVVSNLKIFIDAAYERKEPIDHILLYGPPGLGKTTLAHIIAKELKVNFRSTAGPLLSKAGDLAAILTNLQARDVLFIDEIHRLNRNIEEILYSAMEDFSLDIIVGEGCGARTLRVDIPPFTLIGATTRIGLLSNPLRDRFGIPMHLEFYSTEELTKVIKRAAKVIHTNISNNGAEEISLRSRGTPRIALRLLRRIRDFISVTKQDTITHEFADQALLRLGIDKLGLDRQDIKYLQFIYEANNPIGIDTISSALSEDTGNIEETIEPYLIKINFIQRTPRGRVITQKAISYLNEQTYNM
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: TSSK3_MOUSE
Sequence: MEDFLLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKIIDKMGGPEEFIQRFLPRELQIVRTLDHKNIIQVYEMLESADGKIYLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCGVAHRDLKCENALLQGFNLKLTDFGFAKVLPKSRRELSQTFCGSTAYAAPEVLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKGVSFPTHLGISTECQDLLKRLLEPDMILRPSIEEVSWHPWLAST
What is the function of this protein?
May be involved in a signaling pathway during male germ cell development or mature sperm function.
What are the official names of this protein?
Testis-specific serine/threonine-protein kinase 3, TSK-3, TSSK-3, Testis-specific kinase 3, Serine/threonine-protein kinase 22C.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
Protein: PARPT_MOUSE
Sequence: MEVETTEPEPDCVVQPPSPSDDFSCQMRISEKISPLKTCFKKKQEQKRLGTGTLRSLRPILNTLLESGSLDGVFRARDQNRDESSLHEHIVKKPLEINPSCPPAENSMPVLIPDGTNVEGQLPEAHPSTDAPEQGVPIQDHSFPPETISGTVADSTTGHFQTDLLHPVSGDVPTSPDCVDKVMDYVPGAFQDNSFTIQYILDTSDKLSTELFQDKSEEASLELVFELVNQLQYHTHQENGIEICMDFLQGTCIYGRDCLKHHTVLPYHWQIKRTTTQKWQSVSNDSQEHLERFYCNPENDRMRMKYGGQDFWADLNAMTVFETTEFDQLRRLSTPPCSNSNSIYHTFWKFFCRDHFGWREYPESVVRLIEEANSRGLKEVRFMMWNNHYILHNSFFRREIKRRPLFRSCFILIPYLQTLGGVPTQASLPLEATSSQIICPDGVTSANFYPETWVYMHPSQDFIQVPVSAEDKSYRIIYNLFHKTVPEFKYRILQILRVQNQFLWEKYKRKKEYMNRKMSGRDRIINERHLFHGTSQDVVDGICKHNFDPRVCGKHATMFGQGSYFAKKASYSHNFSKKSSKGVHFMFLAKVLTGRYTMGSHGMRRPPPVNPGSVTSDLYDSCVDNFFEPQIFVIFNDDQSYPYFVIQYEEVSNTVSI
What is the function of this protein?
ADP-ribosyltransferase that mediates mono-ADP-ribosylation of glutamate, aspartate and cysteine residues on target proteins (By similarity).  Acts as a negative regulator of AHR by mediating mono-ADP-ribosylation of AHR, leading to inhibit transcription activator activity of AHR (Probable).
What are the official names of this protein?
Protein mono-ADP-ribosyltransferase TIPARP, ADP-ribosyltransferase diphtheria toxin-like 14, ARTD14, TCDD-inducible poly [ADP-ribose] polymerase.
What is the protein family that this protein belongs to?
Belongs to the ARTD/PARP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: URED1_PSEU2
Sequence: MNAHQSSLPAQTKRTAHIAFSKAPSGASYVSRQEVGYPFHLGRTLTLPQDPPGMAAVYLQSCSGGLFAGEQLHLHLHAGPGTQVHVSTGAATVAHSMLEQSARQTVTLVAEADALLEYLPMATILFPQTRLHSQVNVTLHPGARVLLCDAFCLHTPHGSEGLPDFYRADLQVYSPAGKLLAGDRLAITGADLQRRLPGVSGQRQALATFMLVGQGLPIEDLKRTLRETLRDVADSYQGVSALPNDCGVSVRVMSADAVALRNALHLAWACVRQQLTGLAPRVRRK
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD 1.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CFA36_BOVIN
Sequence: MAAEEEDEVEWVVESIAGFLRGPDWSIPILDFVEQKCEVFDDEEESKLTYTEIHQEYKELVEKLLETYLKEIGINEDQFQEACTSPLAKTRTSQAILQPVLAAEDFTIFKAMMVEKNTEMQLQAIRIIQERNGVLPDCLTDGSDVVSDLEQEEMKILKEVLRKSKEEYDQEEERKRKKQLSEAKTEEHPMQANETAKMSNSQGDGEHFAHPASGLKIPGFEHASMEGPIANLSTLRTEELRQREHYLKQKRDKLMSMRKDMKIKQNQTSEQKGKPAGEVEEMTEKPEMTAEEKQTLLKRRLLAEKLKEEVINK
What is the function of this protein?
May act as an effector for ARL3.
What are the official names of this protein?
Cilia- and flagella-associated protein 36, Coiled-coil domain-containing protein 104.
What is the protein family that this protein belongs to?
Belongs to the CFAP36 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell projection, cilium, flagellum.
Protein: HTPX_XANC5
Sequence: MFNRIFLFLLTNLAVLMLAGIVMSLLGVNPAQMSGLLVMAAIFGFGGSFISLLLSKFMAKRSTGAQVITEPRTPTERWLLETVRRHAQAAGIGMPEVAVYDGPEINAFATGANRNDALVAVSTGLLQNMDQDEAEAVLGHEIAHVANGDMVTMALLQGVLNTFVIVLARVVGGIIDSALSGNREGGRGFAYYIIVFALEMVFGLFATMIAMWFSRRREFRADAGGAQLAGRSKMIAALERLSLNHGQNTLPSQVQAFGISGGVGEGLRRLFLSHPPLTERIAALRAASGSAM
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RUVC_DEHMB
Sequence: MRILGIDPGTLVVGYGIIETANDELTLVGFSSLTPPACAPIPQRLAYIYKGLVEVIELYQPDEVAVESPFADKNIKSALAIGKAQAVALLAAANHSLPVTEYSPACIKSRVAGSGNASKEQIQEMVRLLLNLAEIPQPNDAADALAVAICHHSQRAFTNIISQGDLT
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: SCPB_STAAS
Sequence: MDNHGILESLLFTAGDEGLDEKQLLEILDMSKNQLVELIENYSSHGLMIQRFGTTYVLTTKKEAATYIEQLIEQKSQMKLSQAAMEVLSIIAYNQPLSRSDIELIRSINSDGAVKTLIAKGLVEAKVVNEQRSQQLITTDLFLNVFGISNIEDLPTTEEDDEEMDAFFSNLVNQKGENND
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein B.
What is the protein family that this protein belongs to?
Belongs to the ScpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: APEB_PSEAE
Sequence: MRAELNQGLIDFLKASPTPFHATASLARRLEAAGYRRLDERDAWHTETGGRYYVTRNDSSLIAIRLGRRSPLESGFRLVGAHTDSPCLRVKPNPEIARNGFLQLGVEVYGGALFAPWFDRDLSLAGRVTFRANGKLESRLVDFRKAIAVIPNLAIHLNRAANEGWPINAQNELPPIIAQLAPGEAADFRLLLDEQLLREHGITADVVLDYELSFYDTQSAAVVGLNDEFIAGARLDNLLSCHAGLEALLNAEGDENCILVCTDHEEVGSCSHCGADGPFLEQVLRRLLPEGDAFSRAIQRSLLVSADNAHGVHPNYADRHDANHGPALNGGPVIKINSNQRYATNSETAGFFRHLCQDSEVPVQSFVTRSDMGCGSTIGPITASQVGVRTVDIGLPTFAMHSIRELAGSHDLAHLVKVLGAFYASSELP
What are the official names of this protein?
Probable M18 family aminopeptidase 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M18 family.
Protein: AIM24_VANPO
Sequence: MNNNKLLFAPFANKRFITLIPNSKVVKPAIDDSTGTENLFNVEDLKTTTFNAIGEPSTMASLSVPPRIPLYIRRGCIVSLYNNKSSKDSNISMTHEWKSIIFNLFSYSSITSSLFIKLTSDKSFGLLVAPNFTSNIIPLLSKNSYSTLCTLNLNGSADWNIWGKNSIVAYEGNTSLNIVSNPLFNWRSVFKKRPIYSRKFQTIAGRGNVLLSGSGSIYTIELKTKEDEIVIKSECLLGISGSTQLEIKDSISEQKYISNDIIDQKPQPVLKDVKLSDLNKLTKEEYKIYFKDLYHLTSWWIKKTYIKWISGSTKFLKVKGPRNVLIQTGHNVYLPNIPTKKQETNLSVPEESLLTERDAQVKSEMKYTNYVTISRSGDVKFQSTPNFNETINKLKKN
What are the official names of this protein?
Altered inheritance of mitochondria protein 24, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AIM24 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TP1D_HADIN
Sequence: NECIRKWLSCVDRKNDCCEGLECYKRRHSFEVCVPIPGFCLVKWKQCDGRERDCCAGLECWKRSGNKSSVCAPIA
What is the function of this protein?
This toxin potently and selectively inhibits ASIC1a, an isoform of the gene ASIC1.  It incompletely inhibits ASIC1a activation in a pH-independent and slowly reversible manner.  This toxin acts by binding to and stabilizing the closed state of the channel, thereby impeding the transition into a conducting state.  This toxin may bind to the acidic pocket of ASIC1a, since mutation of a key residue of this pocket (Arg-350) abolishes the ability of the toxin to inhibit ASIC1a.  In vivo, this toxin protects the brain from neuronal injury when administered up to 8 hours after stroke onset.
What are the official names of this protein?
Pi-hexatoxin-Hi1d, Pi-HXTX-Hi1d, Double-knot toxin, DkTx.
What is the protein family that this protein belongs to?
Belongs to the psalmotoxin-1 family. Double-knot toxin subfamily.
What are the subcellular locations of this protein?
Secreted.