PharMolix/UniProtQA huggingface dataset:
Protein: RNH2_MYCVP
Sequence: MPAAWPPRTVIRKSSGLRTLESALYRAGLGPVAGVDEVGRGACAGPLVVAACVLGPNRLESLAALDDSKKLNENERERLFPLIRRYALAYHVVFIPSQEVDRRGVHVANIEGMRRAVAGLSLRPGYVLSDGFRVPGLPMPSLPVVGGDAAAACIAAASVLAKVSRDRLMVAMEDEHPGYGFAEHKGYSTRAHSAALARLGPSSQHRYSFINVRRLVMDGEPEEHGEVGCGKMLVDMPVDGVLHEGQLSR
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAL_SYNE7
Sequence: MAQDVIANGGTPEIGNLATPINSSPFTRTFINALPIYRRGLSSNRRGLEIGMAHGFLLYGPFSILGPLRNTETAGSAGLLATVGLVVILTVCLSLYGNAGSGPSAAESTVTTPNPPQELFTKEGWSEFTSGFILGGLGGAFFAFYLASTPYVQPLVKIAAGVWSVH
What are the official names of this protein?
Photosystem I reaction center subunit XI, PSI subunit V, PSI-L.
What is the protein family that this protein belongs to?
Belongs to the PsaL family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi- pass membrane protein.
Protein: FOLD_SALPA
Sequence: MAAKIIDGKTIAQQVRSEVAQKVQARVAAGLRAPGLAVVLVGSNPASQIYVASKRKACDEVGFVSRSYDLPETTSEAELLALIDTLNADNTIDGILVQLPLPAGIDNVKVLERIAPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTYGLNAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKDLRHHVEHADLLIVAVGKPGFIPGEWIKEGAIVIDVGINRLENGKVVGDVVFDEAAARASYITPVPGGVGPMTVATLIENTLQACIEYHDPQGK
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: BIOF_PSEAB
Sequence: MSFDLASRLASRRAEDLYRQRPLLESAQGPDVVVDGQPLLAFCSNDYLGLANHPEVIAALRAGAERWGVGGGASHLVVGHSGPHHELELALAEFTGRPRALLFSTGYMANLGAVTALVGKGDTVLEDRLNHASLLDAGLLSGARFSRYLHNDPASLAARLDKAEGNTLVVTDGVFSMDGNLADLPALAAVAQARGAWLMVDDAHGFGPLGASGGGIVEHFGLGQEQVPVLIGTLGKGFGTAGAFVAGSEELIETLIQYARPYIYTTSQPPAVACATLKSLELLRRESWRRQHLAALIARFRHGAEALGLTLMDSFTPIQPILVGGSRQAVALAGMLRARGIMVGAIRPPTVPANSARLRVTLSAAHSEAQVDRLLEALGESWRQLSSSLLAEIEAEEGDDA
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: HXD3A_TAKRU
Sequence: MQKATYYDNSGLFGGYTYPKPDSYNYAPQSYTTANLESDFQGSVCPIQTPTVRPPALKDADLNGDCMRQSSNQSNGNQDTNIGEQPGPPLSASSPSPNSSSSQKKKSPSSSANNSATPAITKQIFPWMKETRQNAKQKGNNCASAGRDNGEGQWRGQPGPCGEVSDEKSPPGPSSKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKSKGLAHSPLGHSPDRSPPLSGPNHIGYSGQLQNGLGYDAPSPPSFAKPQQNMYGLAAYTAPLGGCIPQQKRYLGSEYEHHGMQSNGSFASASLQDSPVYVGGNFVDSMPASGPMFNLGHLPHPSSTSVDYSCAAQIPGNHHHGPCDPHPTYTDLTSHQASQGRIQEAPKLTHL
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-D3a.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LSG1_MOUSE
Sequence: MGRRRAPGGGSLGRVLIRQQTQRSRSHRHTDSWLHTSELNDGYDWGRLNLQSVTEQSSLEDFLATAELAGTEFVAEKLNIKFVPPEARTGLLSFEESQRIKKLHEENRQFLCIPRRPNWDRKTSPEELKQAEKDNFLKWRRQLVRLEEEQKLILTPFERNLDFWRQLWRVIERSDIVVQIVDARNPLLFRCEDLECYVKEIDAAKENVILINKADLLTAEQRFAWAVHFEKEGVKVIFWSALAETDHLNGDLKEEVDSVAGDTNKTESESSSLDANEIPHRDLISLSEESASDSGDSKYEDCQEDEEEDWQTCSEEDSVPEEEEGCNADSETQNRKNAENQQVNNDSYLVSKQELLELFKKLHTGKKVKDGQLTVGLVGYPNVGKSSTINTIMGNKKVSVSATPGHTKHFQTLYVEPGLCLCDCPGLVMPSFVSTKAEMICNGILPIDQMRDHVPPVSLVCQNIPRRVLEVTYGINIIKPREDEDPYRPPTSEELLTAYGCMRGFMTAHGQPDQPRSARYILKDYVGGKLLYCHPPPGKDPVAFQHQHQQLLESKVKGGELRLQPGKGRKAKQIENVVDKTFFHQENVRALTKGVQAVMGYKPGHGLVTAAAASAENVPGKPWKKHGNRNKKEKSRRLYKHLDV
What is the function of this protein?
GTPase required for the XPO1/CRM1-mediated nuclear export of the 60S ribosomal subunit.  Probably acts by mediating the release of NMD3 from the 60S ribosomal subunit after export into the cytoplasm (By similarity).
What are the official names of this protein?
Large subunit GTPase 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. LSG1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Endoplasmic reticulum. Note=Shuttles between the Cajal bodies in the nucleus and the endoplasmic reticulum.
Protein: ARGC_RUTMC
Sequence: MIKVGIVGATGYTGLELIRLLNNHPNAKIIALCSRVNTGKAVIEEFPSLIGYVDLDFIIPDDKTLFECDVIFFATPHGVAMNSVGQFLDKGIKIIDLSADFRIKDSSTWSKWYGIVHTQSALLKNAVYGLPEVYSSQIKNATLVANPGCYPTAIILALKPLLKANSINTKSIIADCKSGVSGAGRNSNIATLFCEVNESLKPYNVNQHRHKPEAQQVLTDIANTDVDFIFTPHLIPMTRGMLASVYVDLTKDIDVQELFKNHYQDNRFVHVLSVGVYPQTKSVKGTNNCHIGIQKSNNKLIIMTVIDNINKGASGQAIQNMNLMFGIDEGLGLEQIGLLP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH601_AZOSB
Sequence: MAAKEVKFGDSARERMVAGVNVLANAVKVTLGPKGRNVVLERSFGAPTVTKDGVSVAKEIELKDKFENMGAQMVKEVASKTSDIAGDGTTTATVLAQSIVREGMKFVAAGMNPMDLKRGIDKAVVATIEELKKLSKPCSTNKEIAQVGSISANSDADIGGIIAQAMEKVGKEGVITVEDGKSLNNELDVVEGMQFDRGYLSPYFINNPDKQVAILENPFVLLFDKKISNIRDLLPVLEQVAKAGRPLLIIAEDVDGEALATLVVNNIRGILKTCAVKAPGFGDRRKAMLEDIAILTGGQVIAEEVGLTLEKATLQDLGQAKRIEIGKENTIIIDGAGEASRIEARVKQIRVQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGIVPGGGVALLRARASLAGLKGDNHDQDAGIKIVLRAMEQPLREIVANAGDEASVVVNKVVEGSGNFGYNAATGEYGDMVEMGVLDPTKVTRTALQNAASVASLMLTTDCMVGELAEDKPAGGMPGMGGMGGMGGMDMGM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 1, 60 kDa chaperonin 1, Chaperonin-60 1, Cpn60 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREG_ACTPL
Sequence: MRKYIKIGVAGPVGAGKTALIERLTREIASKYSVAVITNDIYTQEDAEFLTKNSLLPPERIMGVETGGCPHTAIREDASMNLEAVDEMVARFPEVELIFIESGGDNLSATFSPDLADVTIFVIDVAQGEKIPRKGGPGISRSDLLVINKTDLAPFVGADLSVMERDARRMRNGQPFIFTNLMKNENLDGVIGWIEKYALLKNIEDPASLVR
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SIGL_MYCTE
Sequence: MARVSGAAAAEAALMRALYDEHAAVLWRYALRLTGDAAQAEDVVQETLLRAWQHPEVIGDTARPARAWLFTVARNMIIDERRSARFRNVVGSTDQSGTPEQSTPDEVNAALDRLLIADALAQLSAEHRAVIQRSYYRGWSTAQIATDLGIAEGTVKSRLHYAVRALRLTLQELGVTR
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  Extracytoplasmic function (ECF) sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (By similarity).
What are the official names of this protein?
ECF RNA polymerase sigma factor SigL, ECF sigma factor SigL, Alternative RNA polymerase sigma factor SigL, RNA polymerase sigma-L factor, Sigma-L factor.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. ECF subfamily.
Protein: TLR4_PAPAN
Sequence: MTSALRLAGTLIPAMAFLSCVRPESWEPCVEVVPNITYQCMELNFYKIPDNIPFSTKNLDLSFNPLRHLGSYSFLRFPELQVLDLSRCEIQTIEDGAYQSLSHLSTLILTGNPIQSLALGAFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAHNLIQSFKLPEYFSNLTNLEHLDLSSNKIQNIYCKDLQVLHQMPLPNLSLDLSLNPINFIQPGAFKEIRLHKLTLRSNFDDLNVMKTCIQGLAGLEVHRLVLGEFRNERNLEEFDKSALEGLCNLTIEEFRLTYLDYYLDNIIDLFNCLANASSFSLVSVNIKRVEDFSYNFRWQHLELVNCKFEQFPTLELESLKRLTFTANKGGNAFSEVDLPSLEFLDLSRNGLSFKGCCSQSDFGTTSLKYLDLSFNDVITMGSNFLGLEQLEHLDFQHSNLKQMSQFSVFLSLRNLIYLDISHTHTTVAFNGIFDGLLSLKVLKMAGNSFQENFLPDIFTDLKNLTFLDLSQCQLEQLSPTAFDTLNKLQVLNMSHNNFFSLDVFPYKCLPSLQVLDYSLNHIMTSKNQEPQHFPSSLAFLNLTQNDFACTCEHQSFLQWIKDQRQLLVEAERMECATPSDKQGMPVLSVNITCQMNKTIIGVSVFSVLVVSVVAVLVYKFYFHLMLLAGCIKYGRGENIYDAFVIYSSQDEDWVRNELVKNLEEGVPPFQLCLHYRDFIPGVAIAANIIHEGFHKSRKVIVVVSQHFIQSRWCIFEYEIAQTWQFLSSRAGIIFIVLQKVEKTLLRQQVELYRLLSRNTYLEWEDSVLGQHIFWRRLRKALLDGRSWNPEEQ
What is the function of this protein?
Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS).  Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).  Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate.  In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42.  In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to CD36.  This event induces the formation of a heterodimer of TLR4 and TLR6, which is rapidly internalized and triggers inflammatory response, leading to the NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion.  Binds electronegative LDL (LDL(-)) and mediates the cytokine release induced by LDL(-) (By similarity).  Activated by the signaling pathway regulator NMI which acts as damage-associated molecular patterns (DAMPs) in response to cell injury or pathogen invasion, therefore promoting nuclear factor NF-kappa-B activation (By similarity).
What are the official names of this protein?
Toll-like receptor 4.
What is the protein family that this protein belongs to?
Belongs to the Toll-like receptor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Early endosome. Cell projection, ruffle. Note=Upon complex formation with CD36 and TLR6, internalized through dynamin-dependent endocytosis. Colocalizes with RFTN1 at cell membrane and then together with RFTN1 moves to endosomes, upon lipopolysaccharide stimulation.
Protein: GCH1_SYNJA
Sequence: MTLAKPGSGAEFRLNNKANLKSRLVRDLSHAAGQEPEGSESLDPAMVAAVETLLRGIGEDPQREGLKKTPERVVAALKFLTSGYRQSLEDLINGAIFDEGHDEMVLLRDITLFSLCEHHLLPFIGKAHVAYIPRQKVVGLSKIARIVEMYSRRLQVQERLTRQIAEALMTMLDPYGVGVVIEATHMCMVMRGVQKPGSWTVTSSMVGVFQEDPRTREEFLSLIRHPSNL
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: GATC_BARQU
Sequence: MSVDQETVKRVSHLARIAIHDDEIEPMTKELNVILGFVEQLNEVDVNGIEPLTSVMPMALRMREDSVTDGDKVADIVANAPVTEENFFLVSKVVE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: HEM1_CERS4
Sequence: MDYNLALDTALNRLHTEGRYRTFIDIERRKGAFPKAMWRKPDGSEKEITVWCGNDYLGMGQHPVVLGAMHEALDSTGAGSGGTRNISGTTLYHKRLEAELADLHGKEAALVFSSAYIANDATLSTLPQLIPGLVIVSDKLNHASMIEGIRRSGTEKHIFKHNDLDDLRRILTSIGKDRPILVAFESVYSMDGDFGRIEEICDIADEFGALKYIDEVHAVGMYGPRGGGVAERDGLMDRIDIINGTLGKAYGVFGGYIAASSKMCDAVRSYAPGFIFSTSLPPVVAAGAAASVRHLKGDVELREKHQTQARILKMRLKGLGLPIIDHGSHIVPVHVGDPVHCKMISDMLLEHFGIYVQPINFPTVPRGTERLRFTPSPVHDSGMIDHLVKAMDVLWQHCALNRAEVVA
What are the official names of this protein?
5-aminolevulinate synthase 1, 5-aminolevulinic acid synthase, Delta-ALA synthase, Delta-aminolevulinate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
Protein: NUOA_PSESM
Sequence: MPESTGLIAHNWGFAIFLLGVVGLCAFMLGLSSLLGSKAWGRSKNEPFESGMLPTGSARLRLSAKFYLVAMLFVIFDIEALFLFAWSVSVRESGWTGFVEALVFIAILLAGLVYLWRVGALDWAPEGRRNRQAKLKQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SSPB_STRGN
Sequence: MKNKKEVYGFRKSKVAKTLCGAVLGTALIAFADKAVFADEVTETTSTSTVEVATTGNPATNLPEAQGEMSQVAKESQAKAGSKESALPVEVSSADLDKAVADAKSAGVKVVQDETKDKGTATTATDNAQKQDEIKSDYAKQAEEIKTTTEAYKKEVAAHQAETDKINAENKAADDKYQKDLKSHQEEVEKINTANATAKAEYEAKLAQYQKDLATVKKANEDSQQDYQNKLSAYQTELARVQKANAEAKEAYEKAVKENTAKNEALKVENEAIKQRNETAKATYEAAMKQYEADLAAIKKANEDNDADYQAKLAAYQTELARVQKANAEAKEAYDKAVKENTAKNTAIQAENEAIKQRNETAKATYDAAVKKYEADLAAVKQANATNEADYQAKLAAYQTELARVQKANADAKATYEKAVEDNKAKNAAIKAENEEIKQRNAVAKTDYEAKLAKYEADLAKYKKEFAAYTAALAEAESKKKQDGYLSEPRSQSLNFKSEPNAIRTIDSSVHQYGQQELDALVKSWGISPTNPDRKKSRAYSYFNAINSNNTYAKLVLEKDKPVDVTYTGLKNSSFNGKKISKVVYTYTLKETGFNDGTKMTMFASSDPTVTAWYNDYFTSTNINVKVKFYDEEGQLMNLTGGLVNFSSLNRGNGSGAIDKDAIESVRNFNGRYIPISGSSIKIHENNSAYADSSNAEKSLGARWNTSEWDTTSSPNNWYGAIVGEITQSEISFNMASSKSGNIWFAFNSNINAIGVPTKPVAPTAPTQPMYETEKPLEPAPVAPSYENEPTPPVKTPDQPEPSKPEEPTYETEKPLEPAPVAPSYENEPTPPVKTPDQPEPSKPEEPNYETEKPLEPAPVAPSYENEPTPPVKIPDQPEPSKPEEPTYDPLPTPPLAPTPKQLPTPPVVPTVHFHYSSLLAQPQINKEIKNEDGVDIDRTLVAKQSIVKFELKTEALTAGRPKTTSFVLVDPLPTGYKFDLDATKAASTGFDTTYDEASHTVTFKATDETLATYNADLTKPVETLHPTVVGRVLNDGATYTNNFTLTVNDAYGIKSNVVRVTTPGKPNDPDNPNNNYIKPTKVNKNKEGLNIDGKEVLAGSTNYYELTWDLDQYKGDKSSKEAIQNGFYYVDDYPEEALDVRPDLVKVADEKGNQVSGVSVQQYDSLEAAPKKVQDLLKKANITVKGAFQLFSADNPEEFYKQYVATGTSLVITDPMTVKSEFGKTGGKYENKAYQIDFGNGYATEVVVNNVPKITPKKDVTVSLDPTSENLDGQTVQLYQTFNYRLIGGLIPQNHSEELEDYSFVDDYDQAGDQYTGNYKTFSSLNLTMKDGSVIKAGTDLTSQTTAETDATNGIVTVRFKEDFLQKISLDSPFQAETYLQMRRIAIGTFENTYVNTVNKVAYASNTVRTTTPIPRTPDKPTPIPTPKPKDPDKPETPKEPKVPSPKVEDPSAPIPVSVGKELTTLPKTGTNDATYMPYLGLAALVGFLGLGLAKRKED
What is the function of this protein?
May bind sialic acid residues of salivary agglutinin (SAG) in a calcium-dependent reaction.  The interaction of SAG with its receptor in various oral streptococci modulate bacterial colonization of oral tissue and is associated with reduced levels of dental caries.
What are the official names of this protein?
Agglutinin receptor, Adhesin SspB, SSP-5.
What is the protein family that this protein belongs to?
Belongs to the antigen I/II family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor.
Protein: GREA_RUEPO
Sequence: MEKIPMTPSGFAALEAELKQLKSVERPAIIKAIAEAREHGDLSENAEYHSAREKQSFIEGRIKELEGVLSLADVIDPTKLSGAIKFGARVTLVDEDTDEEKTWQIVGEHEANIEKGLLNIKSPIARALIGKDEGDSVEVKTPGGQKSYEILSIEYS
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: NHAP2_KLEP7
Sequence: MDAAAVISLFILGSVLVTCSILLSSFSSRLGIPILVIFLAIGMLAGIDGIGGIPFDNYPFAYMVSNLALAVILLDGGMRTQASSFRVALWPALSLATVGVLITSALTGMMAAWLFKLDLIEGLLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGSNDPMAVFLTITLIEMIQQHQTGLSWMFAVHIIQQFGLGIAIGLGGGYLLLQMINRIVLPAGLYPLLALSGGIMIFAVTTSLDGSGILAVYLCGFLLGNRPIRNRHGILQNFDGLAWLAQIAMFLVLGLLVTPSDLLPIAIPALLLSMWMIFIARPLSVFAGLLPFRGFNLRERVFISWVGLRGAVPIILAVFPMMAGLDNARLFFNVAFFVVLVSLLLQGTSLSWAAKKAKVVVPPISWPISRVGLDIHPENPWEQFVYQLGADKWCIGAALRDLHMPPETRIAALFRNNVLLHPTGSTRLREGDILCVIGREHDLPALGKMFSQSPPVALDQRFFGDFILDAEARFADVAQIYGLDGGEEFREHQQSLGEVVQQLLGAAPVVGDQVEFAGMVWTVAEKENDHVLKVGVRVAEDEAE
What is the function of this protein?
K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.
What are the official names of this protein?
K(+)/H(+) antiporter NhaP2, Potassium/proton antiporter NhaP2.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IOVO_DENAU
Sequence: VATVDCSDYPKPACTLEYMPLCGSDNKTYGNKCNFCNAVVDSNGTLTLSHFGKC
What are the official names of this protein?
Ovomucoid.
What are the subcellular locations of this protein?
Secreted.
Protein: KAX6F_HEMLE
Sequence: IKCTLSKDCYSPCKKETGCPRAKCINRNCKCYGCS
What is the function of this protein?
Blocks voltage-gated potassium channels rKv1. 1/KCNA1 (IC(50)=13 nM), rKv1. 2/KCNA2 (IC(50)=16 nM) and rKv1. 3/KCNA3 (IC(50)=2 nM).
What are the official names of this protein?
Potassium channel toxin alpha-KTx 6.15, Hemitoxin.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 06 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL31B_BACAA
Sequence: MKAGIHPDYKKVVFMDTNTGFKFLSGSTKGSNETVEWEDGNTYPLLKVEISSDSHPFYTGRQKFATADGRVDRFNKKYGLK
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: UXAC_ECO24
Sequence: MTPFMTEDFLLDTEFARRLYHDYAKDQPIFDYHCHLPPQQIAEDYRFKNLYDIWLKGDHYKWRAMRTNGVAERLCTGDASDREKFDAWAATVPHTIGNPLYHWTHLELRRPFGITGKLLSPSTADEIWNECNELLAQDNFSARGIMQQMNVKMVGTTDDPIDSLEHHAEIAKDGSFTIKVLPSWRPDKAFNIEQATFNDYMAKLGEVSDTDIRRFADLQTALTKRLDHFAAHGCKVSDHALDVVMFAEANEAELDSILARRLAGETLSEHEVAQFKTAVLVFLGAEYARRGWVQQYHIGALRNNNLRQFKLLGPDVGFDSINDRPMAEELSKLLSKQNEENLLPKTILYCLNPRDNEVLGTMIGNFQGEGMPGKMQFGSGWWFNDQKDGMERQMTQLAQLGLLSRFVGMLTDSRSFLSYTRHEYFRRILCQMIGRWVEAGEAPADINLLGEMVKNICFNNARDYFAIELN
What are the official names of this protein?
Uronate isomerase, Glucuronate isomerase, Uronic isomerase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.
Protein: SBCD_STAA1
Sequence: MKIIHTADWHLGKILNGKQLLEDQAYILDMFVEKMKEEEPDIIVIAGDLYDTTYPSKDAIMLLEQAIGKLNLELRIPIIMISGNHDGKERLNYGASWFEHNQLFIRTDFTSINSPIEINGVNFYTLPYATVSEMKHYFEDDTIETHQQGITRCIETIAPEIDEDAVNILISHLTVQGGKTSDSERPLTIGTVESVQKGVFDIFDYVMLGHLHHPFSIEDDKIKYSGSLLQYSFSEAGQAKGYRRLTINDGIINDVFIPLKPLRQLEIISGEYNDVINEKVHVKNKDNYLHFKLKNMSHITDPMMSLKQIYPNTLALTNETFNYNEENNAIEISEKDDMSIIEMFYKHITDKELSDIQSKKIKNILENELRKED
What is the function of this protein?
SbcCD cleaves DNA hairpin structures.  These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions.  The complex acts as a 3'->5' double strand exonuclease that can open hairpins.  It also has a 5' single-strand endonuclease activity (By similarity).
What are the official names of this protein?
Nuclease SbcCD subunit D.
What is the protein family that this protein belongs to?
Belongs to the SbcD family.
Protein: AROC_STAAR
Sequence: MRYLTSGESHGPQLTVIVEGVPANLEIKVEDINKEMFKRQGGYGRGRRMQIEKDTVEIVSGVRNGYTLGSPITMVVTNDDFTHWRKIMGAAPISDEERENMKRTITKPRPGHADLVGGMKYNHRDLRNVLERSSARETAARVAVGALCKVLLEQLDIEIYSRVVEIGGIKDKDFYDSETFKANLDRNDVRVIDDGIAQAMRDKIDEAKNDGDSIGGVVQVVVENMPVGVGSYVHYDRKLDGRIAQGVVSINAFKGVSFGEGFKAAEKPGSEIQDEILYNTELGYYRGSNHLGGLEGGMSNGMPIIVNGVMKPIPTLYKPLNSVDINTKEDFKATIERSDSCAVPAASIVCEHVVAFEIAKALLEEFQSNHIEQLQQQIADRRQLNVEF
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: HACE1_XENTR
Sequence: MERAMEQLNRLTRSLRRARTVELPEDNETAVYTLMPMVMADQHRSVLELLSNSKFDVNYAFGRVKRSLLHIAANCGSVECLVLLLKRGADPNYQDISGCTPLHLAARNGQKKCMSKLLEYNADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVTNVDVEDAMGQTALHVACQNGHKTTVLCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKYLPDKNGVTPLDLCVQGGYGETCDILIQHHPRLFQTLIQMTQNEDLRENTLRQVLEHLSQQSEVQYLKILTGLAEVATTNGHKLLSISSSYEAQMKSLLRIVRIFCHVFRIGPSSPNNGNDMGYNGNKTPRNQVFKPLELLWHSLDEWLVLIATELTKNKRDSSNIACILLKQNQLDQQDISLAHQSAIGESGSYDHLSSSTRAEDFESCSAAGKQEPVADGQDVISMTANRLSAVIQAFYMCCSCQMPQGMTSPRFIEFVCKHDDVLKCFVTRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKERCEWFYEHLLAGQPDSDMVHRPVNENDILLVHRDSIFRSSCEVVFKSNCEKLKQGIAVRFHGEEGMGQGVVREWFDILSSEIINPDYALFTQSADGTTFQPNSNSSVNPDHLNYFRFAGEILGLALYHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLKPGGASILVTQENKAEYVQLVTELRMTRAIQPQINGFLQGFHMFIPPSLIQLFDEYELELLLSGMPEIDVNDWMKNTEYTSGYERDDQVIQWFWEVVQELTQEERVLLLQFVTGSSRVPHGGFAYIMGGSGLQNFTIAAVAYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGSYGYTMA
What is the function of this protein?
E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases.  Acts as a regulator of Golgi membrane dynamics during the cell cycle: recruited to Golgi membrane by Rab proteins and regulates postmitotic Golgi membrane fusion.  Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division.
What are the official names of this protein?
E3 ubiquitin-protein ligase HACE1, HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1, HECT-type E3 ubiquitin transferase HACE1.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane. Cytoplasm. Endoplasmic reticulum.