PharMolix/UniProtQA huggingface dataset:
Protein: RPOC_SHEB8
Sequence: MKDLLKFLKQQSKTEEFNGIKIGLASPDLIRSWSFGEVKKPETINYRTFKPEREGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPVAHIWFLKSLPSRIGLMLDMTLRDIERVLYFESFVVIEPGMTSLERGQMLTEETYLDALEEYGDEFEAKMGAEAVLELLRAIDLAKEIEQMREELPSINSETRRKKVTKRLKLMEAFYTSGNKPEWMILKVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQESVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPTLRLHQCGLPKKMALELFKPFIYGKLEGRGLATTIKAAKKMVEREVAEVWDVLDEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPVITPSQDVVLGLYYTSRERINGRGEGMAFMSVAEVEKAYATGAAELHARVKVRITETIIGDTGERTEQRRIVDTTVGRALLSLILPAGLSFDLVNQNMGKKQISKLLNTCYRQLGLKDTVIFADQLMYTGFRFATISGASVGIDDMVIPDEKYTLVADAEAEVLEIQEQFQSGLVTAGERYNKVIDIWASANEKVSKAMMENLSTETVINRDGVEEKQASFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVIEDDCGTHEGLTMKPLIEGGDVVEPLRERVLGRVVALDVFYPGTEDVLAPRNTLLDEAWCDKLEEYSIDEVIVRSVISCDTDFGVCAACYGRDLARGHIINHGEAIGVVAAQSIGEPGTQLTMRTFHIGGAASRASAENNVQVKNSGSLKLHNAKHVTNSDGKLVIVSRSSELAVIDELGREKERYKVPYGTVLEKLEEAAVEAGDVIANWDPHTHPIISEVAGSIKFVDMIDGVTMTRQTDELTGLSSIVILDVGQRGTAGKEMRPMIRLLGANGADLMIPGTEVPAQYFLPGSAIVNLEDNAQINVGDALARIPQESSKTRDITGGLPRVADLFEARKPKEPAILAEISGTISFGKETKGKRRLVITPADGGDHYEEMIPKWRNLNVFEGEKVERGEVIADGPEAAHDILRLRGIHNVANYIVNEVQDVYRLQGVKINDKHIEVIIRQMLRKCLITSAGDTDFLEGEQAEVSRVKIANRELIAQGKVPATFERELLGITKASLATESFISAASFQETTRVLTEAAVGGKSDQLRGLKENVIVGRLIPAGTGYAYHKTRNEARAKKNEPVVVNKITASEAEQNLADLLNLAGSQD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: BUK_EXIS2
Sequence: MSERILTINPGSTSTKIGIFDGTEQVFTKTLRHSAEAVGGPLSDQLNIRRQVVLDVLAQEQIDLKALTAIVGRGGLLRPLVSGTYRVNQEMREDLLNGTFGIHASNLGGLLADEIGQTLSIPAFIVDPVVVDELEPIARLTGLPELERKSIFHALNQKAVAKRYAKENGIPYEQLRLIVAHMGGGITVGAHLNGRVIDVNNGLDGEGAFSPERSGSLPVGQLVELCYSTKYKLEEMKRLVVGSGGLVAHLGTYDAVEIERRIDDGDEKAALLYEAMAYRVAKEIAAQSAVLYGQVDAVILTGGLAYSDRLTKAIEERIAHIGSIIRIPGEDELRALAEGVIRVLRQEEQVKEYGGELTWLENSTSLS
What are the official names of this protein?
Probable butyrate kinase, BK, Branched-chain carboxylic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_RHIL3
Sequence: MFDTHTVEIEWAGRPLKLETGKIARQADGAVLATYGETVVLATVVSAKAPKAGQDFFPLTVNYQEKTYAAGKIPGGYFKREGRPSEKETLVSRLIDRPIRPLFPEGYKNDTQVVVTVIQHDLENDPDVLSMVATSAALTLSGVPFMGPVGGARVGYINGEYVLNPHLDEMDESSLDLVVAGTYDAVLMVESEAKELNEDVMLGAVMFGHKGFQPVLDAIIKLAEVAAKEPRDFQPADYSALESEMLGLAEGELRNAYKITQKADRYAAVDAVKAKVKAHFLPEEGEAKYTAEEVGAIFKHLQAKIVRWNILDTKSRIDGRNLETVRPIVSEVGLLPRTHGSALFTRGETQAIVVATLGTGEDEQYVDSLTGMYKERFLLHYNFPPYSVGETGRMGSPGRREIGHGKLAWRAIRPMLPTPEQFPYTLRVVSEITESNGSSSMATVCGTSLALMDAGVPLAKPVAGIAMGLILEGDRFAVLSDILGDEDHLGDMDFKVAGTADGITSLQMDIKITGITEEIMKVALGQAQGGRVHILGEMSKAITESRGQLGEFAPRIEVMNIPVDKIREVIGSGGKVIREIVEKTGAKINIEDDGTVKIASSSGKEIEAARKWIHSIVAEPEIGQVYEGTVVKTADFGAFVNFFGARDGLVHISQLASERVAKTQDVVKEGDKVWVKLLGFDERGKVRLSMKVVDQATGQEIPNEKKKEEAAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y713_RUEPO
Sequence: MTGPSGAGRSTAINVLEDLGFEAIDNLPMGLLMRLLDGPALRRPLALGLDARNRDFSTEGFLDLSKRLASLEGFQVTTLYLDCSADILLRRFSETRRRHPMSPGSSPLEGVEHELELLRPIREAADTLIDTTALNVHQLRREVERWFAPSGGSMLAISVESFSYKRGLPRGLDMVFDCRFLANPHWQPDLRAADGRDPAVAAYVHADPQYLPFFTRVTDLLQSLLPAFRSEGKAHLSVGFGCTGGQHRSVALTEAVAKALAEAGGQVSIRHREMERRKPDARPD
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein SPO0713.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: LEXA_STAA1
Sequence: MRELTKRQSEIYNYIKQVVQMKGYPPSVREIGEAVGLASSSTVHGHLSRLEEKGYIRRDPTKPRAIEIVSDQTNDNINMEETIHVPVIGKVTAGVPITAVENIEEYFPLPEHLTSTHNSDIFILNVVGDSMIEAGILDGDKVIVRSQTIAENGDIIVAMTEEDEATVKRFYKEKNRYRLQPENSTMEPIYLDNVAVIGKVIGLYREM
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: CYC4_AZOVI
Sequence: MNKALVTLLLTLGITGLAHAAGDAAAGQGKAAVCGACHGPDGNSAAPNFPKLAGQGERYLLKQMQDIKAGTKPGAPEGSGRKVLEMTGMLDNFSDQDLADLAAYFTSQKPTVGAADPQLVEAGETLYRGGKLADGMPACTGCHSPNGEGNTPAAYPRLSGQHAQYVAKQLTDFREGARTNDGDNMIMRSIAAKLSNKDIAAISSYIQGLH
What is the function of this protein?
Diheme, high potential cytochrome c believed to be an intermediate electron donor to terminal oxidation systems.
What are the official names of this protein?
Cytochrome c4.
What are the subcellular locations of this protein?
Periplasm.
Protein: GA2L2_HUMAN
Sequence: MSQPAGGRRKPRTLGPPVCSIRPFKSSEQYLEAMKEDLAEWLRDLYGLDIDAANFLQVLETGLVLCQHANVVTDAALAFLAEAPAQAQKIPMPRVGVSCNGAAQPGTFQARDNVSNFIQWCRKEMGIQEVLMFETEDLVLRKNVKNVVLCLLELGRRAWRFGVAAPTLVQLEEEIEEEVRRELALPPPDPSPPAPPRRQPCHFRNLDQMVQSLVSHCTCPVQFSMVKVSEGKYRVGDSNTLIFIRILRNHVMVRVGGGWDTLGHYLDKHDPCRCTSLSHKPGSFLKPPAPPVQHEVRVQDGPSQTQPTMTISRSQSPPPPVDWKTYTSSDRRLRPPTPSSPRPRRERGAGTGASREMAPFLRCQERSLIPSWRQPTAGDSPPSPQSSSTQKGRDPQCTSSGKREERYPPELPRGRIPTSWVHEETDSWGTDAGNPTPQRLRAIEATTKGISARGPSPLPRSFGPAECLGLRLPLRDEAKGAFFQFREPESVRSPTPVQGLTKIPIRLPPARPPTPGRSFPGATSGSPRTELGRDPIPLRAVTVDLAGSTHGDCSVEVRQEDQQLDIQVMAEARESWDLGLQEQEGRYTPLPLGGNKEQAIYCSLEEEILGNMKLLEVRSACPQGTRSGVIPRSGVYIPRLAGQWPEPGGPYDKAIQELAQGSPSLLKVDLEAWKAAPTGSPKPAVTPGPGSLKGKLGARQSGPRTKASLSAKGTHMRKVPPQGGQDCSASTVSASPEAPTPSPLDPNSDKAKACLSKGRRTLRKPKRVPSIYKLKLRPRIRPRRDHRPEKQPSRIPRPLAYVFLGPARQPPKDRLLRAVLGSKGGEASRVDGASVGEEEEEGKEEKEPAAPLESSPQPPEGLQPHWLNQAPLPPEEESWV
What is the function of this protein?
Involved in the cross-linking of microtubules and microfilaments (PubMed:12584248, PubMed:24706950).  Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (PubMed:24706950).  Enhances ADORA2-mediated adenylyl cyclase activation by acting as a scaffold to recruit trimeric G-protein complexes to ADORA2A (By similarity).  Regulates ciliary orientation and performance in cells located in the airway (PubMed:30665704).
What are the official names of this protein?
GAS2-like protein 2, GAS2-related protein on chromosome 17, Growth arrest-specific protein 2-like 2.
What is the protein family that this protein belongs to?
Belongs to the GAS2 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell membrane. Cytoplasm, cytoskeleton, stress fiber. Cytoplasm, cytoskeleton, cilium basal body. Note=Colocalizes with ADORA2A at neuronal processes (By similarity). Colocalizes with and tracks the tips of microtubule plus ends (PubMed:24706950).
Protein: COBQ_PSEF5
Sequence: MSTLMVQGTTSDAGKSTLVTALCRWLWRQGVSVVPFKPQNMALNSAVTADGGEIGRAQAVQAQAANLAPHTDMNPVLLKPNSDTGSQVIIHGRAVTSMNAVAYHDYKAIAMQAVLASHERLKSAYQVVMVEGAGSPAEINLRAGDIANMGFAEAVDCPVLLIADINRGGVFAHLVGTLELLSPSEQARVKGFIINRFRGDLALLQPGLDWLEARTGKPVIGVLPYVLDLHLEAEDGIDQRQVGKVEQLLKVVVPVLPRISNHTDFDPLRLHPQVDLQFIGPGQAIPAADLIILPGSKSVRGDLAYLRSNGWDRAVARHLRYGGKVLGICGGLQMLGEQVHDPLGLEGAAGSSPGLGLLAFETVLEEEKQLRNVSGRLSLENAAVSGYEIHAGVTRGPALELAAVQLDDGRSDGACSADGQILGTYLHGLFETPAACSALLRWAGLEAVQEVDYHALRERDIERLADLVEHHLDTAALRRLCGL
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: LEAM_RAMVA
Sequence: MFLARNAGRAGYRGVVAYQQAASFSVSSAKAAGSRSSGGSDAGDYAREAAEHAKAGLKDLKNEASWKAKGVANQAAGAFERAKDTVKEGVHDMKRSGSRVFEQGQEEVEAGAQHAKAGYQSAKNAAQDTAATLKDKAGSAWNQAKHVVEDKGEDVVEAVKDTASKVWGKAKHVAEDVKENAQSPGGIADKASDVWSAAKDKAADVLSGAKHTAENLAHKAQAAIHDATASSGSQSQSQSQSQYRQGQQQGRQDQQQSKSQWGQTSPQSPDGFRPQAGQGPQGGKGPGQAGGRR
What is the function of this protein?
Mitochondrial heat soluble protein acting as a molecular shield in water-deficient condition.
What are the official names of this protein?
Group 3 late-embryogenesis abundant protein, mitochondrial, LEAM.
What is the protein family that this protein belongs to?
Belongs to the LEA type 4 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: Y4035_BACAC
Sequence: MGEENQPNYTISQENWSLHRKGYDDQQRHQEKVQEAIKNNLPDLVTEESIVMSNGKDVVKIPIRSLDEYKIRYNYDKNKHVGQGNGDSKVGDVVARDGSGGQKQKGPGKGQGAGDAAGEDYYEAEVSILELEQAFFKELELPNLKRKEMDENRIEHVEFNDIRKTGLWGNIDKKRTMISAYKRNAMRGKASFHPIHQEDLKFRTWNEVLKPDSKAVVLAMMDTSGSMGIWEKYMARSFFFWMTRFLRTKYETVDIEFIAHHTEAKVVPEEEFFSKGESGGTICSSVYKKALELIDNKYSPDRYNIYPFHFSDGDNLTSDNARCVKLVEELMKKCNMFGYGEVNQYNRHSTLMSAYKNIKDENFRYYILKQKADVFHAMKSFFREESGEKMA
What are the official names of this protein?
UPF0229 protein BAMEG_4035.
What is the protein family that this protein belongs to?
Belongs to the UPF0229 family.
Protein: USPB_ECO24
Sequence: MISTVALFWALCVVCIVNMARYFSSLRALLVVLRNCDPLLYQYVDGGGFFTSHGQPNKQVRLVWYIYAQRYRDHHDDEFIRRCERVRRQFILTSALCGLVVVSLIALMIWH
What are the official names of this protein?
Universal stress protein B.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL9_CLOK1
Sequence: MKVILLKDVKTLGKKGEVINASDGYARNYLIPKGFAEEANKTNLHIWNNKKEAERKQKLAEIEAAQKLAAELKGKEINLTVKSGENGRIFGSITGKDISDELNKKFKINIDKKKIVINNIRQLGTYDVEVKLYPEISTKIKVIIAEK
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: PNX31_SCOSU
Sequence: MKAFIVILSIAIVLLLIVSIKETSAKDCKQECVKRYTKGDLTNFLKAEYEPKNRGGICYCEFTCHVKFYIYLKHEMD
What are the official names of this protein?
Putative neurotoxin 1.
What is the protein family that this protein belongs to?
Belongs to the scolopendra neurotoxin 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: TILS_STRP2
Sequence: MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQKELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDFFQEVMKKTGATALVTAHHADDQVETIFMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFLHFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYDLAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKFKSQYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEGELIQQIPVSRETSIHIRHRKTGDVLIKNGHRKKLRRLFIDLKIPMEKRNSALIIEQFGEIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS4_CHRSD
Sequence: MLVIPAIDLKDGQCVRLKQGRMDDSTTYGDDPVAMAARWVETGARRLHLVDLNGAFEGKPVNAEAVTAIARAYPDLPIQIGGGIRTAETIEAYLEAGVSYVIIGTQAVKEPAFVGEMCRRFPGHVIVGLDARDGYVATDGWAEVSTLKAVDLAKRFADDGVSSIVYTDIARDGMMQGVNIAATAELAREGGLPVIASGGVTHLGDIEALLEVADAGILGAITGRAIYEGKLDVAEAQRLCDAQLATRRS
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIE_CAUVN
Sequence: MSNTSASFGFKDVDASLKAGLVRGVFDRVAKNYDIMNDLMSGGVHRLWKDAVAARLNPQPGEVIIDCAGGTGDMARRFAKMARKAQERRGGPDATINIVDYNAEMIMAGIERGGEPEITWTVGDAQRLPLPDAYADAYVISFGIRNVTDINAALREARRVLKPGGRFLCLEFSRPVTEPLAKAYDAYSFKVIPQVGEWVAKDRDAYQYLVESIRRFPDQRTFAGMIEAAGFKRVTFTNFTGGVAALHQGWAI
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: YR46_CAEEL
Sequence: MDNIQTFFDQYVHLPSEISSKHDHAYIILILLSVILILLLLICNLCICYFIRQRRRRELIDYPSNTLQYIPFPRNVRKPYRTESGTSSSNRMMLPPRQHV
What are the official names of this protein?
Uncharacterized protein F47D12.6.
Protein: TRM1_HHV6Z
Sequence: MNSLQSLCVLCARLNECALDLECLKFCDPVIVLSDMANFKKNGIVILHLYQTFFEGIKEQNLLCASALTVYMQVLLKAMYEQVLLLDAALESFMVDQDRKKYFEKVLCLKRCAEHLSINISLNNGVEFIVQLSTLNDIEQLISKINSVYALLLPQEGLQICGKIIDLLTIMCGACMVAKPESYLETKTCMKCYEELTLTPNQGKSLRKRLHGKFCNHLTEQKAFFNIEKNIETIEKDLGEAILNYGTIQSVVTEIKKIFKQQRSAESLHVSDAEKTLKKYNIFSKVPDVIYSLSEFTYWSKISETIVRNVAITLQQLNSCHTLYKQLQNDVSLYLYGEVSEDFLALSENLLTHDERLYVGSIYVSPSRLIDLVTGLSIKNLEESPIFKRLAEEDEVQHKIKSLLHDIRDPQTTETPGRLNTINCMLQTHNLQQEVLARKKAYFQKVSESGYNRVMACIREQESLINKVVSVNVYGNFIFEALSKIMNGFVLRKMYLDGSIRVDSCTYDEHLYIKNNLMPKKLPLELLPDLSEIMYTLLTGPLSDFHKSAYPLPANISMAYGCDHAEMLPHMKEDLARCIEGTIHPSVWMVCEYNEFFNFSGVTDVNDMQKKMWNFIRELTLSVALYNDVFGKRLKIVRIDEEEDLNGNVVLTFNHESPLLFHTGGGMTKFKDVYSLLYCDLQAQLSRETVDVPEGVSYSVRTPNLLDLVRENEQDESIIPGCLFDE
What is the function of this protein?
Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging.  Forms a tripartite terminase complex together with TRM2 and TRM3 in the host cytoplasm.  Once the complex reaches the host nucleus, it interacts with the capsid portal vertex.  This portal forms a ring in which genomic DNA is translocated into the capsid.  TRM1 carries an endonuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.
What are the official names of this protein?
Tripartite terminase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae TRM1 protein family.
What are the subcellular locations of this protein?
Host nucleus. Note=Found associated with the external surface of the viral capsid during assembly and DNA packaging, but seems absent in extracellular mature virions.
Protein: RL22_PROMA
Sequence: MSDLPLAQAHGRFIRGSASKVRRVLDQIRGRTYRDALIMLEFMPYRSTGPITKVLRSAVANAENNLGMDPSSLIIKTASADMGPSMKRYRPRAQGRAFAIKKQTCHISIAVAPSNQSTTTEASD
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: LPXC_POLAQ
Sequence: MMKQRTIAAPVKTVGIGLHSGRKVTIVIKPAPINSGVQFVRIDTPEQSVVPATALAVCDTRLASVIQKDGVRVSTVEHLLSACAGLGLDNLLIELDGEEVPIMDGSAASFLFLIESAGIAEQEAPRQFVVIKKAVEVREGDKLARLEPFFGFKLDFTIDFKHPAVDKTGQRFIVDFAEHAYRSEIGRARTFGFAHEVEALREMGLARGGSLDNAIVLDEHRILNNEELRYEDEFVRHKILDAIGDLYLIGHPIVGAYIAEKSGHALNNALLRKLLDDPSTYEISSFAENKAPAAYSQENQPLFF
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: NUOD_HELPY
Sequence: MAQNFTKLNPQFENIIFEHDDNQMILNFGPQHPSSHGQLRLILELEGEKIIKATPEIGYLHRGCEKLGENMTYNEYMPTTDRLDYTSSTSNNYAYAYAVETLLNLEIPRRAQVIRTILLELNRMISHIFFISVHALDVGAMSVFLYAFKTREYGLDLMEDYCGARLTHNAIRIGGVPLDLPPNWLEGLKKFLGEMRECKKLIQGLLDKNRIWRMRLENVGVVTQKMAQSWGMSGIMLRGTGIAYDIRKEEPYELYKELDFDVPVGNYGDSYDRYCLYMLEIDESVRIIEQLIPMYAKTDTPIMAQNPHYISAPKEDIMTQNYALMQHFVLVAQGMRPPVGEVYAPTESPKGELGFFIHSEGEPYPHRLKIRAPSFYHIGALSDILVGQYLADAVTVIGSTNAVFGEVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SYE_STAAE
Sequence: MSDRIRVRYAPSPTGYLHIGNARTALFNYLYAKHYNGDFVIRIEDTDKKRNLEDGETSQFDNLKWLGLDWDESVDKDNGYGPYRQSERQHIYQPLIDQLLAEDKAYKCYMTEEELEAEREAQIARGEMPRYGGQHAHLTEEQRQQFEAEGRQPSIRFRVPQNQTYSFDDMVKGNISFDSNGIGDWVIVKKDGIPTYNFAVAIDDHYMQISDVIRGDDHISNTPKQIMIYEAFGWEPPRFGHMSLIVNEERKKLSKRDGQILQFIEQYRDLGYLPEALFNFIALLGWSPEGEEEIFSKEEFIKIFDEKRLSKSPAFFDKQKLAWVNNQYMKQKDTETVFQLALPHLIKANLIPEVPSEEDLSWGRKLIALYQKEMSYAGEIVPLSEMFFKEMPALGEEEQQVINGEQVPELMTHLFSKLEALEPFESAEIKKTIKEVQKETGIKGKQLFMPIRVAVTGQMHGPELPNTIEVLGKEKVLNRLKQYK
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_WOLSU
Sequence: MKLFGTDGVRGKAGEKLTAFSAMKLGLAAGIYFRKQSKTNKILVGKDTRRSGYMIENALVSGLTAVGYNVIQIGPMPTPAIAYLTEDMRCDAGIMISASHNPFDDNGIKFFNRFGFKLDEEAEREIEAIYADEALLEASQKSGKEIGASKRIDDVVGRYIVHIKNSFPKELSLHGVRMVLDTANGAAYKVAPTIFSELGAEVFVINDAPNGHNINESCGATQPLMLSEEVKRVRADIGFALDGDADRLVVVDERGEVVDGDKLIGALAMHLKNSHTLEKPLAVATVMSNLALEEFLAKAKIKLLRAGVGDKYVLEMMQKEGANFGGEQSGHLIFSDFAKTGDGLVSALQTMAFVLRSGERASRALNIFDLYPQKLVNLPIKQKKELKEIEGFEALMSEIESQGFRQLIRYSGTENKLRILLEGKDGRALEKWMERCVEFFKATLGG
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: MT21E_BOVIN
Sequence: MILFNLLETQLTRVHSFQEMIKKASVYRHPLANHLMDPEVQKESREDGDDRTVVAEIMRRCFVPAFVTTIPWEGFHFAGHEIRINEATDCYGAVVWPSALVLCYFLETNVKQYNLVDKNVIEIGAGTGLVSIVASLLGAHVTATDLPELLGNLQYNISRNTKTKAKHLPQVKELSWGVALDKNFPRASINFDYILAADVVYAHPFLEELLVTFDHLCKETTVILWVMKFRLEKENKFVDRFEQLFDLEEISSFPSLNIKLYKAMKKNQKSACYPQRRMWKAKPISGRLLL
What is the function of this protein?
Protein-lysine methyltransferase.
What are the official names of this protein?
Protein-lysine methyltransferase METTL21E, Methyltransferase-like protein 21E.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL21 family.
Protein: ERR1_MOUSE
Sequence: MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVTLASGPAPARCLPGHKEEEDGEGAGSGEQGSGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAPVNALVSHLLVVEPEKLYAMPDPASPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGDLGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD
What is the function of this protein?
Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'.  Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter.  Binds to the C1 region of the lactoferrin gene promoter.  Requires dimerization and the coactivator, PGC-1A, for full activity.  The ERRalpha/PGC1alpha complex is a regulator of energy metabolism.  Induces the expression of PERM1 in the skeletal muscle (By similarity).
What are the official names of this protein?
Steroid hormone receptor ERR1, Estrogen receptor-like 1, Estrogen-related receptor alpha, ERR-alpha, Nuclear receptor subfamily 3 group B member 1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Co-localizes to the cytoplasm only in presence of MAPK15.
Protein: BIP8_TOBAC
Sequence: RIPKVQQLLKDYFDGKEPNKGVNPDEAVAYGAAVQGGILSGEGGDETKDILLLDVAPLTLGIETVGGVMTKLIPRNTVIPSKKSQVFTTYQDQQTTVTIQVFEGERSLTKDCRLLGKFDLTGIAPAPRGTPQIEVTFEVDANGILNVKAEDKASGKSEKITITNDKGRLSQEEIERMVKEAEEFAEEDKKVKERIDARNSLETYVYNMRNQINDKDKLADKLESDEKEKIETATKEALEWLDDNQSAEKEDYEEKLKEVEAVCNPIITAVYQKSGGAPGGESGASEDDDHDEL
What is the function of this protein?
Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER.
What are the official names of this protein?
Luminal-binding protein 8, BiP 8, 78 kDa glucose-regulated protein homolog 8, GRP-78-8.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: MNMG_STAAW
Sequence: MVQEYDVIVIGAGHAGVEAGLASARRGAKTLMLTINLDNIAFMPCNPSVGGPAKGIVVREIDALGGQMAKTIDKTHIQMRMLNTGKGPAVRALRAQADKVLYQQEMKRVIEDEENLHIMQGMVDELIIEDNEVKGVRTNIGTEYLSKAVIITTGTFLRGEIILGNMKYSSGPNHQLPSITLSDNLRELGFDIVRFKTGTPPRVNSKTIDYSKTEIQPGDDVGRAFSFETTEYILDQLPCWLTYTNAETHKVIDDNLHLSAMYSGMIKGTGPRYCPSIEDKFVRFNDKPRHQLFLEPEGRNTNEVYVQGLSTSLPEHVQRQMLETIPGLEKADMMRAGYAIEYDAIVPTQLWPTLETKMIKNLYTAGQINGTSGYEEAAGQGLMAGINAAGKVLNTGEKILSRSDAYIGVLIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLRLTDMGYELGMISEERYARFNEKRQQIDAEIKRLSDIRIKPNEHTQAIIEQHGGSRLKDGILAIDLLRRPEMTYDIILEILEEEHQLNADVEEQVEIQTKYEGYINKSLQQVEKVKRMEEKKIPEDLDYSKIDSLATEAREKLSEVKPLNIAQASRISGVNPADISILLIYLEQGKLQRVSD
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.