PharMolix/UniProtQA huggingface dataset:
Protein: RS7_METTP
Sequence: MKVFGKWDASEVEIPDLSVKGYINLKPRIVLHTGGRHAKQQFKKSELHVVERLINKMMRKEKNTGQKQIAYRIVEEAFDIIHSRTKENPLSVLVRAISNAGPREEVVRLKYGGITVPKAVDTAPQRRVDTALMLIAKGAWQASFKSRRSIQNCLADEIIAAANYDVKSFAVSRKDSIERVAKAAR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RISB_EDWI9
Sequence: MKTIQGVVAAPQARVAIAISRFNHFINDSLLEGAIDALKRIGQVSDENITVVWVPGAYELPLTVRALASSGRYDAVVALGTVIRGGTAHFEFVAGECSSGLASVALNTDVPVAFGVLTTETIEQAIDRAGAKAGNKGAEAALTALEMINVLKAIKA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: B2MG_CHETO
Sequence: MAPFVAIALLVLLSLSGLEAIQHAPKIQVYSRHPAENGKPNFLNCYVSGFHPSDIEVDLLKNGKKIEKVEHSDLSFSKDWSFYLLYYTEFTPNEKDEYACRVSHVTFSTPKTVKWDRNM
What is the function of this protein?
Component of the class I major histocompatibility complex (MHC).  Involved in the presentation of peptide antigens to the immune system (By similarity).
What are the official names of this protein?
Beta-2-microglobulin.
What is the protein family that this protein belongs to?
Belongs to the beta-2-microglobulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRHO_SALA4
Sequence: MPVLHNRISNDELKAKMLAESEPRTTISFYKYFTIASPQQTRDALYQVFTALDVFGRVYLAHEGINAQISVPQSKVETFRQQLYTFDPALDGLRLNIALEDDGKSFWVLRMKVRDRIVADGIDDPSFDASNVGDYLKAADVNVMLDDPDAVFIDMRNHYEYEVGHFENALEIPADTFREQLPKAVEMLREHADKKIVMYCTGGIRCEKASAWMKHNGFNKVWHIEGGIIEYARRAREQGLPVRFIGKNFVFDERMGERISDEVIAHCHQCGAPCDSHTNCKNDGCHLLFIQCPQCASKFNGCCSEQCCEELALPEEEQRRRRAGRENGNKIFNKSRGRLNSKLSIPDPAE
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: LMA2L_MOUSE
Sequence: MAAASRPSWWQRWRRRAWARDGAKLLLFLLLLGSGPGPRHVRAGQAVEYLKREHSLSKPYQGVGTSSSSLWNLMGNAMVMTQYIRLTPDMQSKQGALWNRVPCFLKDWELQVHFKIHGQGKKNLHGDGLAIWYTKDRMQPGPVFGNMDKFVGLGVFVDTYPNEEKQHERVFPYISAMVNNGSLSYDHERDGRPTELGGCTAIVRNIRYDTFLVIRYVKRHLTIMMDIDGKHEWRDCIEMPGVRLPRGYYFGTSSITGDLSDNHDVISLKLFELTGVRTPEEEKLHRDVFLPSVDNLKLPEMTVPPTPLSGLALFLIVFFSLVFSVFAIVIGIILYNKWQDQSRKRFY
What is the function of this protein?
May be involved in the regulation of export from the endoplasmic reticulum of a subset of glycoproteins.  May function as a regulator of ERGIC-53 (By similarity).
What are the official names of this protein?
VIP36-like protein, Lectin mannose-binding 2-like, LMAN2-like protein.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Note=Predominantly found in the endoplasmic reticulum. Partly found in the Golgi.
Protein: ATPD_STAA8
Sequence: MVKVANKYAKALFDVSLDTNNLETINEELTVINEAVKDKIEQLRMVDSNPTQTAEQRRELINGVFTDINPYIKNMMYVLADNRHISLIADVFKAFQSLYNGHYNQDFATIESTYELSQEELDKIVKLVTQQTKLSKVIVDTKINPDLIGGFRVKVGTTVLDGSVRNDLVQLQRKFRRVN
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: FAA26_MYCMM
Sequence: MPVTDRSIPSLLKEQADQRPNETAFTFLDYDLDPNGFAETLTWSQVYARACVVADELTMYGVPGDRVAILAPQGLEYIVAFLGALQAGFIGVPLSTPQYGVHDERVSAVLRDSQPVAILTTSAVVGDVTKYASSQDGQPAPSVIEVDLLDLDTPRPQQALPQPASGSAYLQYTSGSTRTPAGVIVSHENVIANVTQSLYGYFGGPDKFPADTTVVSWLPLFHDMGLILGICAPLVTGCTAVLLSPMSFLRRPARWMQLLASHPKCFSAAPNFAFELAVRRTTDEDLAGLDLGDVLGIVSGSERIHVATIKRFTERFAPFNLSPAAVRPSYGLAEATLYVAAPEPGTTPRTVRFDYESLTAGHARPCRADGSVGTELISYGSPDPSAVRIVNPETMIENPSGTVGEIWAHGEHVAMGYWQKPEQSDRTFNARIVNPAPGTPEGPWLRTGDLGVMSNGELFIMGRIKDLVIVDGRNHYPDDIEATIQEITGGRVAAIAVPDNITEQLVAIIELKRRGASAEEAMVKLRSVKREITSAISKSHSLRVADVVLVPPGSIPITTSGKIRRAACVERYRSDGFNRLDVTV
What is the function of this protein?
Catalyzes the activation of long-chain fatty acids as acyl-adenylates (acyl-AMP), which are then transferred to the multifunctional polyketide synthase PpsA for further chain extension (PubMed:25561717).  Catalyzes the adenylation of the long-chain fatty acids eicosanoate (C20) or docosanoate (C22), and potentially the very-long-chain fatty acid lignocerate (C24) (By similarity).  Involved in the biosynthesis of phthiocerol dimycocerosate (DIM A) and phthiodiolone dimycocerosate (DIM B) (PubMed:25561717) (By similarity).
What are the official names of this protein?
Long-chain-fatty-acid--AMP ligase FadD26, FAAL, Acyl-AMP synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: NUOI_YERPB
Sequence: MTLKELVVGFGTQVRSLWMIGLHAFHKRETLMYPEEPVYLPPRYRGRIVLTRDPDGEERCVACNLCAVACPVGCISLQKAEQKDGRWYPEFFRINFSRCIFCGLCEEACPTTAIQLTPDFEMGEFKRQDLVYEKEDLLISGPGKYPEYNFYRMAGMAIDGKQKGEAENEAKPIDVKGLMP
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: OLE15_CORAV
Sequence: MADYQHQQQHQRPADAFKGMFPEKGQAQVQGPSASKVIAVVTLLPLGGFLLLLAGLTFAGTLIGLALSTPLFVLCSPVLVPAAIVIGLAVTGFLTSGAFGITGISSLSWILKYLRGTSVPEQMEHAKRRAQDTAGHLGQKARETGQTVTGKGQEAGKTLEGGRGEEKKT
What is the function of this protein?
May have a structural role to stabilize the lipid body during desiccation of the seed by preventing coalescence of the oil.  Probably interacts with both lipid and phospholipid moieties of lipid bodies.  May also provide recognition signals for specific lipase anchorage in lipolysis during seedling growth.
What are the official names of this protein?
Oleosin Cor a 15.
What is the protein family that this protein belongs to?
Belongs to the oleosin family.
What are the subcellular locations of this protein?
Lipid droplet. Membrane; Multi-pass membrane protein. Note=Surface of oil bodies. Oleosins exist at a monolayer lipid/water interface.
Protein: MURB_DINSH
Sequence: MTDLRGTLTENRPLADLTWLRVGGPADLFFQPADADDLAAFLRADLARPVFVMGVGSNLIVRDGGLRAAVIRLGRGFNGIRIDGTRVRAGAAALDAHVARKAAAAGVDLTFLRTIPGTIGGAVAMNAGCYGTYMADVFVEATALTRAGEAITLTREDLNFRYRQSDLPPGTVITEVVMEGPPGAPEALEARMADQLAKREATQPTKDRTAGSTFRNPAGFSSTGRADDTHEAKAWAVIDAAGMRGAMRGAAQMSPKHPNFLVNTGGATAAELESLGEEVRKKVFQATGHSLHWEVIRIGQPGRTPPA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA_SALHS
Sequence: MDKFRVQGPTTLQGEVTISGAKNAALPILFAALLAEEPVEIQNVPKLKDVDTSMKLLSQLGAKVERNGSVHIDASQVNVFCAPYDLVKTMRASIWALGPLVARFGQGQVSLPGGCTIGARPVDLHITGLEQLGATIKLEEGYVKASVEGRLKGAHIVMDKVSVGATVTIMCAATLAEGTTIIENAAREPEIVDTANFLVTLGAKIAGQGTDRITIEGVERLGGGVYRVLPDRIETGTFLVAAAISRGKILCRNAQPDTLDAVLAKLRDAGADIEVGEDWISLDMHGKRPKAVNVRTAPHPAFPTDMQAQFTLLNLVAEGTGFITETVFENRFMHVPELSRMGARAEIESNTVICHGVETLSGAQVMATDLRASASLVLAGCIAEGTTIVDRIYHIDRGYERIEDKLRALGANIERVKGE
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATC_HALLT
Sequence: MSAVGSSNPEYVVARVRARRGSLYGDEEYRKLTRMGPAEIARFMEESSYGTEINALGSLHGGVDLIEYALNRNLAGQFDDILDWSEGSLYGLIARYLRKFDAWNVKTVIRGVYTDADQSEIEVDLIRAGEFDDRRIRRLLEADSIDAVVEVLEDTIYGDPLREAYAEYEETGVLVPLENAVDRAFYERLLSGLGNDEPTRQYEAFLKAEVDFRNAANALRLARSGADIDPAAYFIEGGELFTRGSLARLARNLDELVEYIADSQYGDELGPALRELEEANSLIAFEHATDAALLAYGDQLGTIHPVSVTPVISYILAKEREVENIRAIARGKEAGLSADEIESELVIT
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit C, V-ATPase subunit C.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase V0D/AC39 subunit family.
Protein: LUXS_HELPY
Sequence: MKTPKMNVESFNLDHTKVKAPYVRVADRKKGVNGDLIVKYDVRFKQPNQDHMDMPSLHSLEHLVAEIIRNHASYVVDWSPMGCQTGFYLTVLNHDNYTEILEVLEKTMQDVLKATEVPASNEKQCGWAANHTLEGAKDLARAFLDKRAEWSEVGV
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD) (By similarity).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: NAGS_ASPNC
Sequence: MSSRTLVGLRSTTSTHLQRSGVAAAAAVSSSSTSSSGSAPRRCLSSASGRQVQQSAEFSSSSKSWDRLGRRAKEKLLDREFFLSLLNSASTKREAKSYLARLKAQHQGTPPLKPAAKQPGVAEAAAPVSSGASSTSFYGASRSVYDSPVFRHDSTPTPPLQDVSERLHLALVKITTPQLLDDSTVNGVAKTLSQLNRLGMACCVVVDPGTAGDSNQLRRIAAEQADRISTAVDAQPDSKSAHIDSVLSVSALNPEAPKVLSRKLLLGPLRDGHIVVLAPIAYTEDVPRAVTVSASDAILALTKELAGLATNPDPDEDPIRTAQRIAGLQEEVSLDRVILLDPLGGIPAFSGPQTSHVFINMEQEFDDIENELLRVWQSAASAKNNLPEEGLPSIADSNPLSKFADTEVVPVPPSQKAYSSDLTLGTSMVEGHINNLRLSQAALAMLPSASSSIITSPLEVANSAQSPGGASPDVSAVGTRRQRNPLIHNLLTDKPLLSSSLPLSRRAALNGRRDSIATQPSHTTFVKRGMPLTIIPNPWLSPWTAKDRPRLGLDDPSIDLPRLVHLIEDSFNRKLDVQDYLNRVNGRLAGLIIAGEYEGGAILTWELPPGVEDDGSEASQARMVPYLDKFAVLKRSQGAGGVADIVFNAMVRSCFPNGVCWRSRKDNPVNKWYFERSQGTWKLSDMNWTMFWTTPGLTEDSQKFRDYEAVCRSIQPSWADDTGVVD
What is the function of this protein?
N-acetylglutamate synthase involved in arginine biosynthesis.
What are the official names of this protein?
Amino-acid acetyltransferase, mitochondrial, Arginine-requiring protein 2, Glutamate N-acetyltransferase, N-acetylglutamate synthase, AGS, NAGS.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GCSH_ACICJ
Sequence: MTETRFSKDHEWVRLDGDVATVGITDHAQSALGDVVFVELPETGRHVDAGEACAVVESVKAASDVYAPLAGTVTEANGALADDPGMVNAQAESGAWFFRMTLDDRAAFDALLTADDYQAFLATL
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: METN_STRPD
Sequence: MNEAIIQLDHIDITFRQKKRVIEAVKDVTVHINQGDIYGIVGYSGAGKSTLVRVINLLQAPTNGKITVDGDVTFDQGKIQLSADALRQKRRDIGMIFQHFNLMAQKTAKENVAFALRHSSLSKTEKEHKVIELLELVGLSERADNYPAQLSGGQKQRVAIARALANDPKILISDEATSALDPKTTKQILALLQELNCKLGLTIVMITHEMQIVKDICNRVAVMQNGVLIEEGSVLDIFSNPKEALTQEFITTATGIDEALEKINQQDIVKHLPANALLAQLKYAGTSTDEPLLNSIYRQFEVTANILYGNIEILDHIPVGDMIVVLEGQAENILAAEKALHEAGVDVSILKRGA
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: THYN1_MOUSE
Sequence: MPRPRKRQTGTAGPDRKKLSGKRTKTENSESTSVKLENSSLEMTTTFKNGGKNLSNYWLMKSEPESRLEKGIDMKFSIEDLKAQPKQTACWDGVRNYQARNFLRAMKLEDEAFFYHSNCKQPGIVGLMKIVKEAYPDHTQFEKSNPHYDPSSKEDDPKWSMVDVQFVRMMKRFIPLEELKTYHQAHKATGGPLKSMTLFTRQRLSVQPLTQEEFDFILSLEETEPS
What is the function of this protein?
Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.
What are the official names of this protein?
Thymocyte nuclear protein 1, Thymocyte protein Thy28, mThy28.
Protein: KCY_ALIFM
Sequence: MTTHSPVVTVDGPSGAGKGTLCMLLAEKLGYNLLDSGAIYRVLALAAIHHGVDLNSEDALVPLAANLDVQFKAEGELVKVILEGEDVSAELRKEETGMAASKVAALPQVREALLRRQRAFSAQPGLIADGRDMGTVVFPNAEVKIFLDASAEERANRRMKQLQQKGLDVKFDRLLSEIQERDDRDRNRAVAPLRPAEDALVLDSTSMNIEEVVVQAITFIESKL
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPO41_RHIME
Sequence: MIDSAAPPSGFCRDCLKEQAAHSRRCLACGSPRLLRHSELYRLTLAHIDCDAFYASVEKRDNPELADKPVIIGGGKRGVVSTACYIARIHGVRSAMPMFKALEACPQAVVIKPDMEKYVRVGREVRAMMQELTPLVQPLSIDEAFLDLSGTERLHHDPPARTLARFAKRVEQEIGITVSVGLSYCKFLAKVASDLQKPRGFSVIGQAEAADFLKAKPVTLIWGVGKAFAATLERDGIRAIGQLQTMEEADLMRRYGTMGRRLYRLSRGLDERSVEIDGEAKSVSSETTFNDDLARQEDLVAHLRGLSEQVAFRLRKSALAGQTVVLKLKTADFKTRTRNRRLESPTRLADRIFRTGLQLLEKEVDGTKYRLIGIGVSDLVDPDLADPPDLVDPQASRRAAAEDAINRLRDKFGKTSVETGYTFGKGRRGQ
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII (By similarity).
What are the official names of this protein?
DNA polymerase IV 1, Pol IV 1.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU2M_YARLI
Sequence: MLILAIISLITFVSMSKLSDNRAIIRLINIYLILVLVLDSFLYLLFLNNQTYTVMGELLIFNSFTFYIDMLIYFIMIVISSLYGYNLYNNNLYKTLFEPKKELIILFLINILGALLIVHSNDFITLFVAIELQSYSIYLITAIYNSSYKASKASMLYFFMGGILSILIAYSINTYYSVLNSYTLHSLDSLIINTLDLNLILIALSLGLLFKIGIAPLHKWLISIYENTPILITIYISLIPKISILSYLVLSNISINSLVISILAILTLLVGSVGGLLQIKIKRLLAFSGLTNAGYMMLLLLLNNNEFSYLYYITQYSISHLAIFMIIIFSIYYINYINNQYNPIIYVNQLKGLIHDNAYLVLSMAIVVFSFIGIPPLLGFFGKLNILMSILNNGYYFISIVLIVASLISALYYLYLLNVSIQDKNNILINSNETVSSVLSYILSSLIILITFGFIYNSLIIDIFNVYFN
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: YCF12_EUGVI
Sequence: MNIVIVQLGSLALITLAGPIIIVLLFLKQGNL
What is the function of this protein?
A core subunit of photosystem II (PSII).
What are the official names of this protein?
Photosystem II reaction center protein Ycf12.
What is the protein family that this protein belongs to?
Belongs to the Ycf12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: ACET2_ORYSJ
Sequence: MAAGLGVKAAPFTYVAHALAVAAAVMVLVWCISFRGGLAFEADNKNLIFNVHPVLMLIGYIILGSEAIMIYKIFPKLNHDTTKLIHLILHAIAIVLGAVGIYCAFKFHNESGIANLYSLHSWLGIGTISLYGIQWIFGFVAFFYPGAAPHVRRGALPWHVLFGLFVYVLTLATAELGLLEKLTFLQSSGLDKYGAEAFLVNFTGLVVALFGAAVVVAAVAPAHVEEPEGYAPIPVN
What is the function of this protein?
Two-heme-containing cytochrome.  Catalyzes ascorbate-dependent trans-membrane electron transfer by utilizing a concerted H(+)/e(-) transfer mechanism (By similarity).
What are the official names of this protein?
Probable ascorbate-specific transmembrane electron transporter 2, Cytochrome b561-2.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NU4LM_PHOLR
Sequence: MSMVYANIFLAFIMSLMGLLMYRSHLMSSLLCLEGMMLSLFVMMTVTILNNHFTLASMAPIILLVFAACEAALGLSLLVMVSNTYGTDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: IL12B_MARMO
Sequence: MCLQQLVISWVSLVWLASPLLAIWELEKNVYVVELDWHPDTPGEKVVLTCDTPEEDGITWTSEQSSEVLGSGKTLTILVKEFEDAGHYTCRRGGEVLSQMLLLLHKNEDGIWSTDILKKKEPENKNLVTCEAKNYSGRFTCWWLTAISTDVNFSVKSHRGSSDPQGVTCGEATLSAERVKIEQREYKKYSVQCQEDNACPTAEETLPITVVVDAVHKLKYENYISSFFIRDIIKPDPPKNLKMKPSKTPQQVEVTWEYPDSWSTPHSYFSLTFSVQVQGKKKKRSNTLHVDKTSVTVTCQKGAKVSVQARDRYYNSSWSEWATMSCP
What is the function of this protein?
Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity.  IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues.  IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of pro-inflammatory cytokines.  IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis (By similarity).
What are the official names of this protein?
Interleukin-12 subunit beta, IL-12B, Cytotoxic lymphocyte maturation factor 40 kDa subunit, CLMF p40, IL-12 subunit p40.
What is the protein family that this protein belongs to?
Belongs to the IL-12B family.
What are the subcellular locations of this protein?
Secreted.
Protein: GPMA_CHLCH
Sequence: MIKLVLLRHGESQWNRENRFTGWHDIDLTDQGRIEASNAGKLLRAEGFTFDIAYTSVLKRAIRTLWHVLDEMDLMWLPVTKSWRLNERHYGALQGLNKAETAQKYGEEQVLVWRRSYDTPPPALEKSDARYPGSQARYASLSEAEVPLTECLKDTVARFLPLWHETIAPEIRKGRNVIIAAHGNSIRALVKYLDNVSEDDIVGINIPTGIPLVYELDDDLKPIRSYYLGDQDALKKAQEAVAKQGKA
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: CSN9_XENLA
Sequence: MKPAVDEMFPEGAGPYVDLDEAGGSSGLLMDLAADEKAVHADFFNDFEDLFDDEDIQ
What is the function of this protein?
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes.  The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity.  May play a role in cell proliferation.
What are the official names of this protein?
COP9 signalosome complex subunit 9.
What is the protein family that this protein belongs to?
Belongs to the CSN9 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Nucleus, nucleoplasm.
Protein: SECA1_STAA8
Sequence: MGFLSKILDGNNKEIKQLGKLADKVIALEEKTAILTDEEIRNKTKQFQTELADIDNVKKQNDYLDKILPEAYALVREGSKRVFNMTPYKVQIMGGIAIHKGDIAEMRTGEGKTLTATMPTYLNALAGRGVHVITVNEYLSSVQSEEMAELYNFLGLTVGLNLNSKTTEEKREAYAQDITYSTNNELGFDYLRDNMVNYSEDRVMRPLHFAIIDEVDSILIDEARTPLIISGEAEKSTSLYTQANVFAKMLKQDEDYKYDEKTKAVHLTEQGADKAERMFKVENLYDVQNVDVISHINTALRAHVTLQRDVDYMVVDGEVLIVDQFTGRTMPGRRFSEGLHQAIEAKEGVQIQNESKTMASITFQNYFRMYNKLAGMTGTAKTEEEEFRNIYNMTVTQIPTNKPVQRNDKSDLIYISQKGKFDAVVEDVVEKHKAGQPVLLGTVAVETSEYISNLLKKRGIRHDVLNAKNHEREAEIVAGAGQKGAVTIATNMAGRGTDIKLGEGVEELGGLAVIGTERHESRRIDDQLRGRSGRQGDKGDSRFYLSLQDELMIRFGSERLQKMMSRLGLDDSTPIESKMVSRAVESAQKRVEGNNFDARKRILEYDEVLRKQREIIYNERNSIIDEEDSSQVVDAMLRSTLQRSINYYINTADDEPEYQPFIDYINDIFLQEGDITEDDIKGKDAEDIFEVVWAKIEAAYQSQKDILEEQMNEFERMILLRSIDSHWTDHIDTMDQLRQGIHLRSYAQQNPLRDYQNEGHELFDIMMQNIEEDTCKFILKSVVQVEDNIEREKTTEFGEAKHVSAEDGKEKVKPKPIVKGDQVGRNDDCPCGSGKKFKNCHGK
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 1.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: SHOC2_NEMVE
Sequence: MRRTKGRTDSPDVQSLNINADYGEAASLTADDSTAHKSDKKHDPEAKKQVTITVQPGVKPKPTVKKRSTPSADLDIHKEIQKCREEGATRLDLSKAAVTVLPKELKELTSLRELYLYGNRIAVLPPEVGLLPNLETLALSENNLTTLPDNLVKLTKLKVLDLRHNKIKEIPDVIYKLTTLTTLYLRFNRISVVESGIGNLKLLERLSLRENKIKILPRVIGQLVHLVTLDISHNHIENLPAEIGNCVHMTSLDLQHNDIPSLPDSIGRLTAMTRLGLRYNQLSSLPDSLANCSGIDEFNIEGNNIAELPEKLLSSLKNLTSLTLSRNKFEVFPAGPPKQFCQVNTFIMEHNRMQKIPFGVFNKAKYLSKLNVKDNQLTSLPLDFGSWISLVELNVATNQISKLPEDIQWLVNLEVLILSNNLLKKLPRGIGALRKLRVLDIEENKLESIPTEIEYLRSLERLVLQSNCLGSLPRSIGYLSSVTYLSVGENELVSVPQEIGNMESLEQLYLNDNENLQSLPYELVLCGSLQIMSIENCPLSALPSQIVAGGPSLVIQYLRLQGPYNGMVDTGVPTSDV
What is the function of this protein?
Acts as a Ras effector and participates in MAPK pathway activation.  Probably acts as a regulatory subunit of protein phosphatase that specifically dephosphorylates Raf kinase and stimulate Raf activity at specialized signaling complexes upon Ras activation (By similarity).
What are the official names of this protein?
Leucine-rich repeat protein soc-2 homolog.
What is the protein family that this protein belongs to?
Belongs to the SHOC2 family.