PharMolix/UniProtQA huggingface dataset:
Protein: ATRD_EMEND
Sequence: MSPLETNPLSPETAMREPAETSTTEEQASTPHAADEKKILSDLSAPSSTTATPADKEHRPKSSSSNNAVSVNEVDALIAHLPEDERQVLKTQLEEIKVNISFFGLWRYATKMDILIMVISTICAIAAGAALPLFTILFGSLASTFQRIMLYQISYDEFYDELTKNVLYFVYLGIGEFVTVYVSTVGFIYTGEHATQKIREYYLESILRQNIGYFDKLGAGEVTTRITADTNLIQDGISEKVGLTLTALATFVTAFIIAYVKYWKLALICSSTIVALVLTMGGGSQFIIKYSKKSLDSYGAGGTVAEEVISSIRNATAFGTQDKLAKQYEVHLDEAEKWGTKNQIVMGFMIGAMFGLMYSNYGLGFWMGSRFLVDGAVDVGDILTVLMAILIGSFSLGNVSPNAQAFTNAVAAAAKIFGTIDRQSPLDPYSNEGKTLDHFEGHIELRNVKHIYPSRPEVTVMEDVSLSMPAGKTTALVGPSGSGKSTVVGLVERFYMPVRGTVLLDGHDIKDLNLRWLRQQISLVSQEPVLFGTTIYKNIRHGLIGTKYENESEDKVRELIENAAKMANAHDFITALPEGYETNVGQRGFLLSGGQKQRIAIARAVVSDPKILLLDEATSALDTKSEGVVQAALERAAEGRTTIVIAHRLSTIKTAHNIVVLVNGKIAEQGTHDELVDRGGAYRKLVEAQRINEQKEADALEDADAEDLTNADIAKIKTASSASSDLDGKPTTIDRTGTHKSVSSAILSKRPPETTPKYSLWTLLKFVASFNRPEIPYMLIGLVFSVLAGGGQPTQAVLYAKAISTLSLPESQYSKLRHDADFWSLMFFVVGIIQFITQSTNGAAFAVCSERLIRRARSTAFRTILRQDIAFFDKEENSTGALTSFLSTETKHLSGVSGVTLGTILMTSTTLGAAIIIALAIGWKLALVCISVVPVLLACGFYRFYMLAQFQSRSKLAYEGSANFACEATSSIRTVASLTRERDVWEIYHAQLDAQGRTSLISVLRSSLLYASSQALVFFCVALGFWYGGTLLGHHEYDIFRFFVCFSEILFGAQSAGTVFSFAPDMGKAKNAAAEFRRLFDRKPQIDNWSEEGEKLETVEGEIEFRNVHFRYPTRPEQPVLRGLDLTVKPGQYVALVGPSGCGKSTTIALLERFYDAIAGSILVDGKDISKLNINSYRSFLSLVSQEPTLYQGTIKENILLGIVEDDVPEEFLIKACKDANIYDFIMSLPEGFNTVVGSKGGMLSGGQKQRVAIARALLRDPKILLLDEATSALDSESEKVVQAALDAAARGRTTIAVAHRLSTIQKADVIYVFDQGKIVESGTHSELVQKKGRYYELVNLQSLGKGH
What is the function of this protein?
Pleiotropic ABC efflux transporter involved in the protection of the cells against a wide range of toxic compounds (PubMed:10954082).  Confers resistance to the azole fenarimol via efflux transport (PubMed:10954082).  May also be involved in the secretion of penicillin (PubMed:10954082).
What are the official names of this protein?
ABC multidrug transporter atrD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYI_STRT1
Sequence: MKLKETLNLGKTSFPMRAGLPNKEPIWQKEWEEAKVYQRRQELNQGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIEQVLAKQGVKRKELDRAEYLKMCRDYALSQVDKQREDFKRLGVSADWENPYVTLTPDYEAAQIRVFGEMAKKGYIYQGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGKGVLDTDTYIVVWTTTPFTVTASRGLTVGADIEYVLVKPAGETRKFIVASELLNSLSEKFAWEEVEVLNTYRGDELNQIVTEHPWDSEVDELVILGEHVTTDSGTGIVHTAPGFGEDDYNVGVANGLEVVVTVNERGIMMENAGPDFAGKFYDKVAPIVMEKLGDLLLAKEEISHSYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGDWVISRQRAWGVPLPIFYAEDRTPIMTEETIEHVAKLFEEHGSVIWWERDAKDLLPEGFTHPGSPNGEFTKENDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSSLITSVANHGVAPYKQLLSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTSVDTSNDVRISMDILSQVSESYRKIRNTLRFLIANTSDFNPTTDAVAFEDLRSVDQYMTIRFNQLVKNIRDAYENFEFLTIYKSLVNFINVELSAFYLDFAKDVVYIESAKSLERRQMQTVFYDILVKITKLLTPILPHTAEEIWSYLEFENEDYVQLSELPEAEDFANQDALLEKWNAFMDFRGKAQKALEEARNEKVIGKSLEAHLTIYPDAEVKELLESLNTNLAQLLIVSALTIAEGDVPESAVRFQGVSFTVERAEGEVCDRCRRIDPTTKERSYNATICNHCASIIEENFAEVVAEGFEV
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3595_CITK8
Sequence: MTKQPEDWLDDVPGDDIEDEDDEIIWVSKSEIKRDAEELKRLGAEIVDLGKNALDKIPLDADLRAAIELAQRIKMEGRRRQLQLIGKMLRQRDVEPIRQALDKLKNRHNQQVVLFHKLEQLRDRLIVEGDDAVEEVLSLWPNADRQQLRSLIRNAKKEKEGNKPPKSARQIFQYLRELAENEE
What are the official names of this protein?
UPF0307 protein CKO_03595.
What is the protein family that this protein belongs to?
Belongs to the UPF0307 family.
Protein: TRUB_SHIF8
Sequence: MSRPRRRGRDINGVLLLDKPQGMSSNDALQKVKRIYNANRAGHTGALDPLATGMLPICLGEATKFSQYLLDSDKRYRVIARLGQRTDTSDADGQIVEERPVTFSAEQLAAALDTFRGDIEQIPSMYSALKYQGKKLYEYARQGIEVPREARPITVYELLFIRHEGNELELEIHCSKGTYIRTIIDDLGEKLGCGAHVIYLRRLAVSKYPVERMVTLEHLRELVEQAEQQDIPAAELLDPLLMPMDSPASDYPVVNLPLTSSVYFKNGNPVRTSGAPLEGLVRVTEGENGKFIGMGEIDDEGRVAPRRLVVEYPA
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: TPS1_CAEEL
Sequence: MTDTATGVHSNANGVEKVPTPVFSIEGEPTQETAPTRMDPFDRPKNDNDPFEDALKRCHKILEKLDCPFVTGKEKDLDESDDMTENEDHDEMANEDDGIPSNEKKVETRKMDCTSGQLLAPKLPEKAESISSASESSEDSESVAILKYTVRTCYAIWKKRQKNSEIALKGLMIVLELCLSQPSARDDAFSALLETLGYNTVTFWKAVVPQIYNSDLSYATQYREALLFSLVLYDVNHSKNRLRELYAAVPGVRQSMLGIRAKQFGERYRHLQMKIARSRASSRMSSKMGSEENLPAMASMMNDVVFDEEPHTQSPLVDMSHDKQRVINVSNAPPVSISRKTSGSWEIKQGSGGLVACVDPVMSADKKNIWLSNLGVNMQEELKEHSTSTNSLGLPLIKQACAGEVFCVLERNEKKEELTPKQQAVESDMSLLSVLNTYNKHSYQLNPVVVNQDDYNTYYGGISNGLLWPALHNLPQYISPCFDDPELLREQWCAYVRVNYLFAINAARNSRAQDFIWIHDYHLMLCGQIMRSLESSLDIGFFIHIPFQPPANFMTKYKTVADPIMRALLRFTKVGFQTSRDRDTFVKLVAKHIKRTKIEYDSRLDRYTIEHDGWTCSLGVFPVSIKIADFVNIAKNPQTIIEAEEIKKQIMGRSADGGQLFFSVERFDYTKGISEKLRAWQRYFEKYPDRIGKDVLFQVAVTNRRSVDSYRQYQDDVLAVADLINQKFKSEDYPEWKPVIFETDGLPRTRLIAHYLAMDIGVVTPSKDGMNLVAKEMLVCNPTASLVLSTGAGTEVQLSNAQFYSEQEGKCYHRVEEISNTEAFADNFFAAATESKETRTKHGEKINQFLCVHDIDEWSDQFLDPKWTHEVISQCEVKQLGQFYGLMSRTAQVRRQIVECVLKGLPIRPHFRYSLENAKNSLESSCKSGTKLSLEADEESGEEKGFEITYDIHDELSEMEKDLAFLAFIQSDEYENAEEFIKTLGSFYEGGPVLFKNEVKQAAEMLQQGIHYNTFFTDRDGTLKSYACSYPTSVQPAYSAVIQAQFARRCATFCAIVTTAPLLHTGILEVATIPEGYYAYGASAGREWYLNPAQQFKDRSFSAIDLNLMNKVFDIIEELLERPEFRIFKWIGSGIQKHCGHITIAKQDVNGTIPSRKVIRLYEQLVKIVNDFDPNGTTLTMRESDLDFKIYVKAKLKGRIFNKGHGIRLVRERLKPNMSKGNCLVCGDNESDIPMLEECLKLAGSKVYTIWVTADTNLQEKVTQLCDRFSCSNIHFVSCPQVLLGAMAYATAHTLVDERNRKLDYYYDSDTPMDQEESSTLGASLGTSFGN
What is the function of this protein?
Catalyzes the production of trehalose from glucose-6-phosphate and UDP-alpha-D-glucose in a 2 step process.
What are the official names of this protein?
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 1, Trehalose-6-phosphate synthase 1, UDP-glucose-glucosephosphate glucosyltransferase 1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the gob-1 trehalose phosphatase family.
Protein: VM3SB_TRIST
Sequence: MIEVLLVTICLAVFPYQGSSIILESGNVNDYEVVYPRKVTAVPKGAVQQKYEDAMQYEFKVNGEPVVLHLEKNKELFSEDYSETHYSPDGREITTYPSVEDHCYYHGRIQNEADSTASISACNGLKGHFKLQGETYLIEPLKLPDSEAHAVFKYENVEKEEEAPKMCGVTETNWKSDEPIKKASQLVVTAEQQRFPRRYVKLAIVADHRMYTKHKKNLKPWVFQMVNSVHQIYRSMNVLIALVYLNIWKKNDKITAQSASNVTLDLFGNWRETVLLKRKRHDCAQLLTAIDFDGPTIGRAHVSSVCDPKRSTGIVQNYTEINLVNAVIMAHELGHNLGMDHDGNQCNCHACIMSAVINNPPSERFSGCSMGYYQTFLTAYNPQCILNALSKRDIITPPVCGNELLEEGEECDCGSPENCQYQCCNATTCKLHSWVECESGECCEQCRFKKAGAVCRAARTECDIPENCTDQSADCPTDSFHRNGQPCLYNHGYCYNGNCPVMHYQCYGLFGPNATVGQDGCFDANDRGDEYFYCRKENEKYIPCAQEDVKCGRLFCTYIYDINLCRYDYSANGMVAQGTKCADGKVCNSNRQCADVNTAY
What is the function of this protein?
This metalloproteinase-disintegrin-like impairs hemostasis in the envenomed animal.
What are the official names of this protein?
Zinc metalloproteinase-disintegrin-like stejnihagin-B, Snake venom metalloproteinase, SVMP.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-III subfamily. P-IIIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SUB9_ARTOC
Sequence: MGFFRTLFSFSIFALSLADTSKFIGLDDVDNIIPNSYIVVMKGAVTEAEFKDHQVWASRIHRRSKRDGAADGLDGLKTTFDFQGFKAYCGTFDKESIERITRSSDVDYVEADRVVKMAALNTQRNAPSWGLGRISHKKAGSFDYVYDSDAGSGITIYGVDTGIDIHHPDFGGRATWGVNTVDSENSDQNGHGTHTAGTFAGATYGVAKKARIIAVKVLNAEGTGSTSGVIQGIEWSTNHASSNGLSGKAAMNLSLGVRSSSVFNSAAEAAQRSGIFLAVAAGNDGFSPASARGVCTVAATDAQDQATSWSNYGSTVALYAPGDKILSIYPNGGTATLSGTSMASPHVCGVGAYLMALEGIGPGRVCDRIKQLALESVKNPGPDTTRRLLYNGSGA
What is the function of this protein?
Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity.
What are the official names of this protein?
Subtilisin-like protease 9.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SEPF_BACCN
Sequence: MSWSKVKYFFFDTPEEKEAAQYAYEKEQIEMKKQQEPPEQQDVPFTKVQPKQNVVSIETAKQSSKVVLLEPRTYSEAQGIADHLKGKRAVVINLQRMSTDQAVRIVDFLSGTVYAIGGDIQKLGPKTFMCTPENVDIVGAISELFGEEEETNIKRW
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: AATA_PENRW
Sequence: MLHILCQGTPFEIGYEHGSAAKAVIARSIDFAVDLIRGKTKKTDEELKQVLSQLGRVIEERWPKYYEEIRGIAKGAERDVSEIVMLNTRTEFAYGLKAARDGCTTAYCQLPNGALQGQNWDFFSATKENLIRLTIRQAGLPTIKFITEAGIIGKVGFNSAGVAVNYNALHLQGLRPTGVPSHIALRIALESTSPSQAYDRIVEQGGMAASAFIMVGNGHEAFGLEFSPTSIRKQVLDANGRMVHTNHCLLQHGKNEKELDPLPDSWNRHQRMEFLLDGFDGTKQAFAQLWADEDNYPFSICRAYEEGKSRGATLFNIIYDHARREATVRLGRPTNPDEMFVMRFDEEDERSALNARL
What is the function of this protein?
Nonribosomal peptide synthetase; part of the gene cluster that mediates the biosynthesis of penicillin, the world's most important antibiotic (PubMed:1368505, PubMed:2120195, PubMed:2110531).  The first step of the pathway is performed by the trimodular NRPS acvA that produces the tripeptide N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine (LLD-ACV or ACV) via condensation of the 3 residues L-2-aminoadipate, L-cysteine and L-valine (PubMed:9266851, PubMed:9355751, PubMed:19686863, PubMed:21889568).  The precursor amino acids for penicillin biosynthesis are withdrawn from the vacuolar amino acid pool by the MFS-type transporter penV (PubMed:8416970, PubMed:22777282).  Each of the constituent amino acids of the tripeptide acv are activated as aminoacyl-adenylates with peptide bonds formed through the participation of amino acid thioester intermediates (PubMed:9266851, PubMed:21889568).  The tripeptide ACV is then cyclized to form isopenicillin N (IPN) by the isopenicillin N synthase ipnA that forms the beta-lactam nucleus (PubMed:1368505, PubMed:1369045, PubMed:1588566).  Finally, the alpha-aminoadipyl side chain is exchanged for phenylacetic acid by the isopenicillin N acyltransferase aatA to yield penicillin (PubMed:2120195, PubMed:2110531, PubMed:1368505).  This step occurs in the peroxisomal matrix and the penM and paaT transporters are involved in the isopenicillin N and phenylacetic acid import into the peroxisome, respectively (PubMed:23053082).
What are the official names of this protein?
Isopenicillin-N N-acyltransferase, IAT, IPN acyltransferase, Acyl-coenzyme A:6-aminopenicillanic-acid-acyltransferase 40 kDa form, Penicillin biosynthetis cluster protein aatA.
What is the protein family that this protein belongs to?
Belongs to the peptidase C45 family.
What are the subcellular locations of this protein?
Peroxisome matrix. Note=The unprocessed preprotein is translocated inside peroxisomes and regulates its self-processing.
Protein: PUR9_LACDB
Sequence: MKRALVSVSDKNNLVPFVKGLVANDYEIVSTGGTKRVLDEAGIPTISVEDVTGFPEILDGRVKTLNPYIHGGLLARRELPEHVATLKEHKITPIDLVCVNLYPFKQTIEKPDVTLAEAIENIDIGGPSMVRSASKNYRDVTIVVDQADYDQVLAEIEKDGSTSLETRARLAAKAFRLTASYDALISQYLTEKAGETAPEKLTLTYDLKEAMRYGENSHQKAWLYEDALPKAFSVLQAEQLNGKELSYNNIKDADEALRCVREFSKPTVVAMKHMNPCGIGQGNTLEEAWDRAYVADPVSIFGGVIALNRKVDLATAEKMHKIFLEIIIAPDYDEDALAALKTKKKNLRILKLDFSKKDEATSKETVSVMGGLLVQDQDVLDEDFADWECVTEAKPTQEQLESLLFAWKAVKHTKSNAIVVANNERTLGVGAGQPNRIDSEKIAIDHAAEALDDRAVLASDAFFPFSDCVEYAGKHGIKAIVQPGGSVRDQESIDMANKYGIAMVFTGVRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: FADB_ECOBW
Sequence: MLYKGDTLYLDWLEDGIAELVFDAPGSVNKLDTATVASLGEAIGVLEQQSDLKGLLLRSNKAAFIVGADITEFLSLFLVPEEQLSQWLHFANSVFNRLEDLPVPTIAAVNGYALGGGCECVLATDYRLATPDLRIGLPETKLGIMPGFGGSVRMPRMLGADSALEIIAAGKDVGADQALKIGLVDGVVKAEKLVEGAKAVLRQAINGDLDWKAKRQPKLEPLKLSKIEATMSFTIAKGMVAQTAGKHYPAPITAVKTIEAAARFGREEALNLENKSFVPLAHTNEARALVGIFLNDQYVKGKAKKLTKDVETPKQAAVLGAGIMGGGIAYQSAWKGVPVVMKDINDKSLTLGMTEAAKLLNKQLERGKIDGLKLAGVISTIHPTLDYAGFDRVDIVVEAVVENPKVKKAVLAETEQKVRQDTVLASNTSTIPISELANALERPENFCGMHFFNPVHRMPLVEIIRGEKSSDETIAKVVAWASKMGKTPIVVNDCPGFFVNRVLFPYFAGFSQLLRDGADFRKIDKVMEKQFGWPMGPAYLLDVVGIDTAHHAQAVMAAGFPQRMQKDYRDAIDALFDANRFGQKNGLGFWRYKEDSKGKPKKEEDAAVEDLLAEVSQPKRDFSEEEIIARMMIPMVNEVVRCLEEGIIATPAEADMALVYGLGFPPFHGGAFRWLDTLGSAKYLDMAQQYQHLGPLYEVPEGLRNKARHNEPYYPPVEPARPVGDLKTA
What is the function of this protein?
Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle.  Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA.  It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
Protein: ACHA_ELEEL
Sequence: SEDETRLVKNLFSGYNKVVRPVNH
What is the function of this protein?
Upon acetylcholine binding, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
What are the official names of this protein?
Acetylcholine receptor subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-1/CHRNA1 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: KAD7_MOUSE
Sequence: MECDAVIYNITENVQQVEEALWAVSALNEEISHFEKRKVFILLSTVMTWARSKPLDPDDNEVPFTEEDYRRRKHHPNFLDHINAEKIVLKFGKNAKKFATYVVASGLQYGAEGGILHTFFKMAWLGEVPALPVFGDGTNCIPAIHVVDLAGVIQNIIDHVPKLHYLVAVDEAVHTLEDLVKCISKNTGPGKIQKVPKENAFLTKDLTQEYLDHLLVNLRMEALFVKENFNIRWVAQTGFVENINSILKEYKQSRGLLPIKICILGPPAVGKSSISEELAKYYKLHHIKMKDVIAEAIAKLEAIVAPKDSVEGEEEGEEEEEEENVDDAQELLDGIKESMEQNAGRLEDQYIIRFVKEKLKSMPCRNQGFILDGFPKTYDQAKDLFNQEEEEEEEEIRGKIFPYDKLITPEFVCGLDASDEFLKERVMNLPESVVAGTHYSQDRFLRSLSHYRDINTDDETVFNYFDELEIHPIHIDVGKLEDAQNRLAIKQLIKEIGKPRNYGLTDEEKAEEEKKAAEERLAKEAAQTAELEHKEAMEMAEKIARWEEWNKRLEEVKREERELLEVQSVPLRNYLMTYVMPTLMQGLNECCKVRPEDPVDFLAEYLFKNNPEMQ
What is the function of this protein?
Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.  Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP.  Also displays broad nucleoside diphosphate kinase activity.  Involved in maintaining ciliary structure and function.
What are the official names of this protein?
Adenylate kinase 7, AK 7, ATP-AMP transphosphorylase 7.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the dpy-30 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell projection, cilium, flagellum. Note=Detected along the full length of sperm flagellum, where it colocalizes with alpha-tubulin.
Protein: SYIM_ARATH
Sequence: MSSFFKSFAGNPREAAAMAMVQSSSYRVLSGKSCSNLRRNTPLDSFLAKGRSSVKAFSFLYVSRFSTEPNNEFGHSSKRRSRGPVMAAKKASEGEKQEDGKYKQTVDLPKTGFGMRANSLTREPELQKLWEENQVFKRVSDNNNGGSFILHDGPPYANGDLHMGHALNKILKDIINRYKLLQNYKVQYVPGWDCHGLPIELKVLQSLDQEVRKELTPLKLRAKAAKFAKATVKTQMESFKRFGVWADWNNPYLTLDPEYEAAQIEVFGQMALKGYIYRGRKPVHWSPSSRTALAEAELEYPEGHISKSIYAIFKLVGGAKTSLLDEFIPNIYLAVWTTTPWTMPANAAVAVNAKLQYSVVEVQSFSEDESTVTSNKKKIPGKVLKNQQKLFVIVATDLVPALEAKWGVKLSISKTFLGSDLENCRYTHPIDNRDCPVVIGGDYITTESGTGLVHTAPGHGQEDYATGLKYGLPLVSPVDDEGKFTEEAGQFRGLSVLGEGNTAVVSYLDENMSLVMEESYAHKYPYDWRTKKPTIFRATEQWFASVEGFRTATMDAINNVKWVPHQAVNRISAMTSSRSDWCISRQRTWGVPIPAFYHVKTKEPLMNEETINHVKSIISQKGSDAWWYMSVEDLLPEKYRDKAADYEKGTDTMDVWFDSGSSWAGVLGKREGLSFPADVYLEGTDQHRGWFQSSLLTSIATQGKAPYSAVITHGFVLDEKGMKMSKSLGNVVDPRLVIEGGKNSKDAPAYGADVMRLWVSSVDYTGDVLIGPQILRQMSDIYRKLRGTLRYLLGNLHDWRVDNAVPYQDLPIIDQHALFQLENVVKNIQECYENYQFFKIFQIIQRFTIVDLSNFYFDIAKDRLYTGGTSSFTRRSCQTVLSTHLLSILRVIAPIVPHLAEDVWQNLPFEYRNEDGSAAEFVFELKWPTLNEQWLSFPAEDVLFWQRLLELRTEVNKVLELARNEKMIGSSLEAKVYLHTADAGMAAKLLEMSEAKNEADTLQRIFITSQVEVLSSMEKEMISSVQHTGEYVEGENKVWIGVSRAEGSKCERCWNYSGQVGSFSDHPTLCGRCFSVIVANPPEPAVAAVNSLA
What are the official names of this protein?
Isoleucine--tRNA ligase, chloroplastic/mitochondrial, Isoleucyl-tRNA synthetase, IleRS, Protein OVULE ABORTION 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Plastid, chloroplast. Mitochondrion.
Protein: METN1_BURMA
Sequence: MIEIRNLSQRFEGPRGWIEALHNVNLTIPQGEVFGIIGRSGAGKSTLVRTINLLTRPSEGSVFVGGRDLTQLSAAELRGARRDIGMIFQHFNLLSSRTVFDNVALPLELAGVKRAQIEATVLPLLDLVGLAAQKDRYPAQISGGQKQRVGIARALASKPKVLLSDEATSALDPETTRAILDLLRRINRELGLTIVLITHQMEVIKDVCDRVAVLDAGRVVEEGNVIDVFMRPHHEVTRALIGDVIAQELPPAMKARVAERLKTGSGHLLRLAFTGSGVDQPILSETIRRYELDFNILHGQIDEIQGRAFGSLAVLATGEPGKVGQAFAYLREQGVVVEELSYVE
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: VCX1_SCHPO
Sequence: MIERLKIAKNRLEAMNSFNFPAQDRHERAPLLGSEYDHSMARQLSLLNVVGMTKSVLMSSYFNLMLVFVPIGLIAGWFEWNAKSVFILNMLAIIPLASLLSFATEQLSIISGPTLGALLNASFGNAIELIVGVLALKRGELRIVQSSLLGSILSNLLLVFGMCLVTTGIRREITTFNITVAQTMIAMLALSTATILIPATFHYSLPDNANSENALLHVSRGTAVIVLIVYVLLLVFQLKTHKHVCHDPSEVEEETEPRILGLRSSIAMLAIVTVFVSLCADYLVGSIDQLVEEVNISKTFVGLVILPVVGNAAEHVTAIVVSYRGQMDLALGVAIGSSIQIALFLAPFLVIVGWIISQPLTLYFESLETVILFVSVFLVNYLIQDGATHWLEGVQLLALYAIVVLAFFYYPQ
What is the function of this protein?
Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane.  Involved also in manganese ion homeostasis via its uptake into the vacuole (By similarity).
What are the official names of this protein?
Vacuolar calcium ion transporter, Vacuolar Ca(2+)/H(+) exchanger.
What is the protein family that this protein belongs to?
Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: AT2L2_MOUSE
Sequence: MAADTRAKAVTLDLRRRLLSSSCRLFFPEDPVKIIRGQGQYLYDEQGREYLDCINNVAHVGHCHPTVVQAAHEQNLVLNTNSRYLHDNIVDYAQRLSETLPEQLSVFYFLNSGSEANDLALRLARQYTGHQDVVVLDHAYHGHLSSLIDISPYKFRNLGGQKEWVHVAPLPDTYRGPYREDHPNPAEAYANEVKHVISSAQQKGRKIAAFFAESLPSVSGQIIPPAGYFSQVAEHIHRAGGLFVADEIQVGFGRIGKHFWAFQLEGEDFVPDIVTMGKSIGNGHPVACMATTQAVSRAFEATGVEYFNTFGGNPVSCAVGLAVLDVLKTEQLQAHATNVGSFLLEHLTQQKAKHPIIGDVRGTGLFIGVDLIKDETLRTPATEEAEYLVSRLKENYILLSIDGPGKNILKFKPPMCFNVDNAQHVVAKLDDILTDMEEKVRSCETLRIKHPPEDTHPTQILLTRQQD
What is the function of this protein?
Catalyzes the pyridoxal-phosphate-dependent breakdown of 5-phosphohydroxy-L-lysine, converting it to ammonia, inorganic phosphate and 2-aminoadipate semialdehyde.
What are the official names of this protein?
5-phosphohydroxy-L-lysine phospho-lyase, Alanine--glyoxylate aminotransferase 2-like 2.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RS19_BORDL
Sequence: MARSIKKGPFIEKSLYQKVLASSGKEKRVVIKTYSRTSTIIPEMVSLTISVYNGKSFIPVYITEDLVGHKLGEFSPTRIFRGHAKSDKKGRK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: DAPB_STAA8
Sequence: MKILLIGYGAMNQRVARLAEEKGHEIVGVIENTPKATTPYQQYQHIADVKGADVAIDFSNPNLLFPLLDEDFHLPLVVATTGEKEKLLNKLDELSQNMPVFFSANMSYGVHALTKILAAAVPLLDDFDIELTEAHHNKKVDAPSGTLEKLYDVIVSLKENVTPVYDRHELNEKRQPQDIGIHSIRGGTIVGEHEVLFAGTDETIQITHRAQSKDIFANGAIQAAERLVNKPNGFYTFDNL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_BURL3
Sequence: MARVCQVTGKAPMSGNNVSHANNKTKRRFLPNLQNRRFWVESENRWVRLRVSNAGLRLIDKNGIDSVLADLRARGEA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: UNG_MOUSE
Sequence: MIGQKTLYSFFSPTPTGKRTTRSPEPVPGSGVAAEIGGDAVASPAKKARVEQNEQGSPLSAEQLVRIQRNKAAALLRLAARNVPAGFGESWKQQLCGEFGKPYFVKLMGFVAEERNHHKVYPPPEQVFTWTQMCDIRDVKVVILGQDPYHGPNQAHGLCFSVQRPVPPPPSLENIFKELSTDIDGFVHPGHGDLSGWARQGVLLLNAVLTVRAHQANSHKERGWEQFTDAVVSWLNQNLSGLVFLLWGSYAQKKGSVIDRKRHHVLQTAHPSPLSVHRGFLGCRHFSKANELLQKSGKKPINWKEL
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
[Isoform 1]: Mitochondrion. SUBCELLULAR LOCATION: [Isoform 2]: Nucleus.
Protein: K1C14_HUMAN
Sequence: MTTCSRQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSSRFSSGGACGLGGGYGGGFSSSSSSFGSGFGGGYGGGLGAGLGGGFGGGFAGGDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEIKDYSPYFKTIEDLRNKILTATVDNANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQSQLSMKASLENSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHLSSSQFSSGSQSSRDVTSSSRQIRTKVMDVHDGKVVSTHEQVLRTKN
What is the function of this protein?
The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro.
What are the official names of this protein?
Keratin, type I cytoskeletal 14, Cytokeratin-14, CK-14, Keratin-14, K14.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Expressed in both as a filamentous pattern.
Protein: YR561_MIMIV
Sequence: MARGKKTQETGSSKRRSKVQEEEEHVEGSEEEVEEPEQKSSKRGSRKTTNSTSNKKKSVKKVESDDDDEDDLSELDVVVEDDNPVETSDNDEVATTPQQEKSSRSRKNRGDHESHDDNSDNEEQGDRGNRREHKPRPKVDPNTPIGKLATDQILQFLQERGEESFNPQLKHGARQLLNQLLGKYNGQRYGSKRGGPPRGSFGQRGGFNSRGRGMPPRMRQGDTRDTRDTRDTRLRFNTTQSNRRELNDQSDDLYND
What are the official names of this protein?
Uncharacterized protein R561.