PharMolix/UniProtQA huggingface dataset:
Protein: GREA_CERS4
Sequence: MTRAGFTALDDELKTLKTVERPAVIRSIAEAREHGDLSENAEYHAAREKQSFIEGRIKELEAILSLAEVIDPAKLSGSIKFGATVTILDEETEEERTYQIVGEAEADIEAGLLNIKSPLARALIGKDEGDSIEVKTPGGERGYEVVSVRFV
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: RS8_SALEP
Sequence: MSMQDPIADMLTRIRNGQAANKAAVTMPSSKLKVAIANVLKEEGFIEDFKVEGDTKPELELTLKYFQGKAVVESIQRVSRPGLRIYKRKDELPKVMAGLGIAVVSTSKGVMTDRAARQAGLGGEIICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: ATPL_CAMLR
Sequence: MKKIVFLMLALSGFAFAAEGSMNQWLASFSILAAGLGLGVAALGGAIGMGNTAAATIAGTARNPGLGGKLMTTMFIALAMIEAQVIYALVIALIALYANPFQALVAA
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYW_CALS4
Sequence: MKRVFSGVQPSGDIHIGNYLGAMRQFVALQDDYDCFFCVVDLHALTVPQDPVELKKNTIELAALYMAIGLDPKKVTLFVQSHVSAHAELAWLLQCITYFGELSRMTQFKEKSKGKESVSVGLFTYPDLMAADILLYKTHYVPVGEDQKQHLELTRDVAQRFNNRFGETFVIPEPMILKFGARIMSLTNPTKKMSKSDADPNNRVNLLDDPDTIYRKIMKAVTDSESEIRLDWEKKPGISNLLTIYSLFTGMEVDEVVNKFKGQGYGTLKKELAEVVIDKLSVIQKNYRDISEEEVLRVLKEGAERAEAVAVETLKEVKEKMGLILRD
What is the function of this protein?
Catalyzes the attachment of tryptophan to tRNA(Trp).
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WALK_BACSU
Sequence: MNKVGFFRSIQFKITLIYVLLIIIAMQIIGVYFVNQVEKSLISSYEQSLNQRIDNLSYYIEQEYKSDNDSTVIKDDVSRILNDFTKSDEVREISFVDKSYEVVGSSKPYGEEVAGKQTTDLIFKRIFSTKQSYLRKYYDPKSKIRVLISAKPVMTENQEVVGAIYVVASMEDVFNQMKTINTILASGTGLALVLTALLGIFLARTITHPLSDMRKQAMELAKGNFSRKVKKYGHDEIGQLATTFNHLTRELEDAQAMTEGERRKLASVIAYMTDGVIATNRNGAIILLNSPALELLNVSRETALEMPITSLLGLQENYTFEDLVEQQDSMLLEIERDDELTVLRVNFSVIQREHGKIDGLIAVIYDVTEQEKMDQERREFVANVSHELRTPLTTMRSYLEALAEGAWENKDIAPRFLMVTQNETERMIRLVNDLLQLSKFDSKDYQFNREWIQIVRFMSLIIDRFEMTKEQHVEFIRNLPDRDLYVEIDQDKITQVLDNIISNALKYSPEGGHVTFSIDVNEEEELLYISVKDEGIGIPKKDVEKVFDRFYRVDKARTRKLGGTGLGLAIAKEMVQAHGGDIWADSIEGKGTTITFTLPYKEEQEDDWDEA
What is the function of this protein?
Member of the two-component regulatory system WalK/WalR involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons.  Phosphorylates WalR.
What are the official names of this protein?
Sensor histidine kinase WalK.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NAC89_ARATH
Sequence: MDTKAVGVSKDTAASMEASTVFPGFKFSPTDVELISYYLKRKMDGLERSVEVIPDLEIYNFEPWDLPDKSIVKSDSEWFFFCARGKKYPHGSQNRRATKMGYWKATGKERDVKSGSEVIGTKRTLVFHIGRAPKGERTDWIMHEYCVKGVSLDDAMVVCRVRRNKEYNSGTSQKAPKPNSSAEKHAKVQNGATSSGSPSDWDNLVDFYLAGESGEKLLAEMAESSENLQVDNDEDFFADILRDEIINLDEAVMTGNTPNEVPTLESASMEIRVLPLPNMIDKQMSSLLEERPSQKKKGKDATESLSSCFVGLYSIKSVNKARWDVIIGVVALIAMLFYLE
What is the function of this protein?
Transcription factor involved in plant cell division.
What are the official names of this protein?
NAC domain-containing protein 89, ANAC089, Protein FRUCTOSE-SENSING QUANTITATIVE TRAIT LOCUS 6.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Relocalization from the cytoplasm into the nucleus is induced by auxin treatment and in association with PAS1.
Protein: HUTG_AROAE
Sequence: MSHKDEEDRGPWHGRIDVHEGPRALRWHQCVKMLAPEAPPGIVLLGFPCDLGVRRNHGRAGAAEGPAALRRTLANLAWHGEWPVYDAGDAGDVGASTHDAGEQTLETMQGDYARRITALLEAGHVPIGLGGGHEIAWAAWQGFAVHAIREPHPPRIGILNVDAHFDLRTAPAGNSGTPFRQIAADCGVRDWNFRYCVLGIAEAANTAALFDRARALGVAFRLDEEMGARDLDATASTVRDFLAGIDWLYLTLCLDALSGACAPGVSAPATIGVEPAVVEAVIRIAVASGKLRLADVAELNPSLDPDGRTARLAARLVWRLAREIARRPCDVRSGLHLPARD
What is the function of this protein?
Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.
What are the official names of this protein?
Formimidoylglutamase, Formiminoglutamase, Formiminoglutamate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: GAS7_HUMAN
Sequence: MSGARCRTLYPFSGERHGQGLRFAAGELITLLQVPDGGWWEGEKEDGLRGWFPASYVQLLEKPGMVPPPPGEESQTVILPPGWQSYLSPQGRRYYVNTTTNETTWERPSSSPGIPASPGSHRSSLPPTVNGYHASGTPAHPPETAHMSVRKSTGDSQNLGSSSPSKKQSKENTITINCVTFPHPDTMPEQQLLKPTEWSYCDYFWADKKDPQGNGTVAGFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEPVDQLLRKVDPAKDRELWVREHKTGNIRPVDMEI
What is the function of this protein?
May play a role in promoting maturation and morphological differentiation of cerebellar neurons.
What are the official names of this protein?
Growth arrest-specific protein 7, GAS-7.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPD_DESAP
Sequence: MIKGAVAARYAQALFDVARDNNRIAETENELRGFMRLLDESRDLQQVLYNPQVPVELKKEIVREAFGKELSGTTLNFLCLVLDRRREVYLKGIADHFIALANETRNIIEAEVTSALELSVVHKVNLMQVLSRMTGKELRIRYQVDPDIIGGLVVRLGDRIIDGSIKRQLERLKDSIRETKVG
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: VKTHC_DENAN
Sequence: WQPPWYCKEPVRIGSCKKQFSSFYFKWTAKKCLPFLFSGCGGNANRFQTIGECRKKCLGK
What is the function of this protein?
Potent blocker of high-voltage-activated calcium ion channels in the nanomolar range, particularly the L-type channels in cerebellar granule cells.  The sensitivity of L-, N- and P-type channels to CAC is tissue and species-dependent.  Blocks the L-type current of cardiac cells, depressing cardiac contractility.
What are the official names of this protein?
Kunitz-type serine protease inhibitor homolog calcicludine, CAC, L-type calcium channel blocker.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: GPDA_ANADE
Sequence: MRATVLGAGSWGTALASLLAGKGYTVTSWDKDAAVLDDIARNHRNERYLPGLHLPPTLHASAEVAKALEGAELVVLAVPSHAVRPVVIEAKRHVHAGTPIVCVAKGIELDTLMTMTEVVEDVLPVPLHPYLAVLSGPSFAKEVAKGLPTAVTVAARWERIAKQVQDAFHTKTFRPYTSGDVVGCEIGGCVKNVVAIAAGISDGMGFGANAMAALVTRGLAEITRLAVRKGANPLTLSGLAGLGDLVLTCSSDLSRNRTVGRGLAEGKTADAIQRELGQVAEGVRNARSARELAKRLGVEMPITEAIYRVLYEGLAPREAVTALMMRETKPEL
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHSO_SCHPO
Sequence: MAPAEKAFVLRKKMDTAIEDRPGQTLTDDHQVKVAIKATGICGSDVHYWKEGGIGDFILKKPMILGHESAGVVVEVGKGVSSLKPGDPVAVEPGCVCRLCDYCRSGRYNLCPHMEFAATPPYDGTLRTYYITTEDFCTKLPKQISVEEGALFEPMSVAVHAMTRGNLKCGSRVLVMGCGTVGLLMMAVAKAYGAIDIVAVDASPSRVEFAQKYVGAKPFTPIAAKENESLPDYAQRYKQAIIEKYGEFDFAVDATGVGICIHTAVLALKRGGTFVQAGNGKPVIDFPINHIINYEINVLGSFRYAHGCYKQSLFLVSNGLVDVKPLITHRFAFKDALKAYETVASGEEGVLKVIIGGPDA
What is the function of this protein?
Polyol dehydrogenase that catalyzes the reversible NAD(+)-dependent oxidation of various sugar alcohols.  Is active with D-sorbitol (D-glucitol) as substrate, leading to the C2-oxidized product D-fructose (By similarity).  Suppresses growth arrest induced by a p53 tumor mutant in fission yeast (PubMed:8223615).
What are the official names of this protein?
Sorbitol dehydrogenase, SDH, Polyol dehydrogenase, Protein tms1.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: OBG_STRPF
Sequence: MSMFLDTAKISVQAGRGGDGMVAFRREKYVPNGGPWGGDGGKGGSVIFRVDEGLRTLMDFRYNRKFKAKSGEKGMTKGMHGRGAEDLIVFVPQGTTVRDAETGKVITDLVEHGQEVVIAKGGRGGRGNIRFATPRNPAPEIAENGEPGEERQLELELKILADVGLVGFPSVGKSTLLSVVSSAKPKIGAYHFTTIVPNLGMVRTKSGDSFAMADLPGLIEGASQGIGLGTQFLRHIERTRVILHVIDMSASEGRDPYEDYVSINNELETYNLRLMERPQIIVANKMDMPEAQENLKAFKKKLAAQYDEFDDLPMIFPISSLAHQGLENLLEATAELLAKTDEFLLYDEADLVDEEAYYGFAETEKDFEITRDDDATWVLSGEKLERLFVMTNMERDESIMKFARQLRGMGVDEALRERGAKDGDLVRIGKFEFEFVD
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y06M_BPT4
Sequence: MILKTRWYDLDDGDDGIPVDRVDWNGCSEDTKKRLIREFRMGYQAAKPFTVTDDKFVCIQNGRAKLTNADWFTDKKVLLWYIISLPISSFVFYFFIKIQWTE
What are the official names of this protein?
Uncharacterized 12.2 kDa protein in e-segB intergenic region.
Protein: SMAD5_HUMAN
Sequence: MTSMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQPNNTPFPLSPNSPYPPSPASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDNSQPMDTSNNMIPQIMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS
What is the function of this protein?
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase.  SMAD5 is a receptor-regulated SMAD (R-SMAD).
What are the official names of this protein?
Mothers against decapentaplegic homolog 5, MAD homolog 5, Mothers against DPP homolog 5, JV5-1, SMAD family member 5, SMAD 5, Smad5, hSmad5.
What is the protein family that this protein belongs to?
Belongs to the dwarfin/SMAD family.
Protein: CH058_HUMAN
Sequence: MMGRRRAFAVDGRDGAGEGLARGCIVPGVTSTYRRIPDAAHGCSSWERGDKFRGVGREALFLKLASRDSGVEMAVGDSPLAALPGLSQDSLDFESSGSSEPPAQVGRLLASQKLGEVLERSRRLPTAPTSLSGQHRSLRLASKPEREVPLGAGQQESMEADTDLEAGLEEEAVGGLGPGAWACLPGQGLRYLEHLCLVLEQMARLQQLYLQLRIQRPPGDPGEEESTRAPLPSPLHTPGNRGQGPWELLSQTEHTGAKAASPPKVEVPSANPPRLPETPVEPTYHLPSSQGHKRDISHWDKVKVLLNRICRRSHHHPEPPAPPDGSDPRIESRDLPERPQCRPHRKTFMPSLVVKKQRAKNLSVG
What are the official names of this protein?
Uncharacterized protein C8orf58.
Protein: HSLV_BORRA
Sequence: MNFKGTTVIAIRRAGKTVVAADGQVTFGYTVLKSNAVKIRKLVNGKILAGFAGSTSDAITLFEKFEEKVKSREDGIIDIKRAAVDLAKDWRADKILHKLEAMMLVADSDNILLISGTGDVVEPEEDVISIGSGGNYAYSAALAYMENKKLSAADIAFKALKIAARVCIYTNSNIVLEEIG
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_HYDS0
Sequence: MEKLVIVGAQWGDEGKGKIVDLLSKDYETAVRYQGGNNAGHTVIVEGKKYILHLVPTSILHKHTKGIIAQGMVIDLEVLSKEIKDLEVLDIENRLFISDRAHIILPYHKILDRLFEKKSNIGTTLKGIGPTYMMKYARKGIRMVDLKDEDIFFNRLEENLEFTKELCEKVYNERFELNKDEVAEDIFRLFKPIEKNIKNTFKIIQTSKSVIFEGAQGVMLDIDIGTYPYVTSSNSSTLGLSNGTGLHPKYFTDAKFVGVSKAYTTRVGAGPFPTELKDEIGDALRDFGHEYGSTTGRPRRCGWLDLVALKYACDTNGFDEIILTKLDVLDIFDEIKVCIAYENFEDFPSSLKDMENARPIYKTLKGWKATTKAARDKSKLPKEALDYIMFIEDYLNTKVSMLSTGPAREDYLYL
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_BORBR
Sequence: MSEAAHSGAAPADLVELGRIASAYGVKGWVKVQPHSAQAEVLRTVSHWWLTRPAPQAARGVVASVPRAYQVLQARVHGGAVVAQLAGIDDRDQAEALRGCLVQAARSAFPAPADDEYYWVDLIGCALYSDADGESRLLGVVDEVFDNGAHAVLKVLRQQLQPGQPGPVPLVDPKGRPLEELVPFVRAHIRHVDLAARRIDSDWPLDY
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2979_ARATH
Sequence: MAFAWCVRRSASKLASACGQARSISAVVNRPSLALNPSPLSPFVSRGFLYTMAVDKLSSEQTLHLVIDSELNSALQTDDPNLNEEMAPGSFPLKIRDKPGDQSVTLTAYYNDERIHVDVGMPYLGDDVIDVFGPNNDELSFPLVVTVIKKNGVSIEFTCQAYADYIDLTDLTVHDYQYQMGETDWPRFKNLDDNLKKAFHRYLATRLDANITKLLHKYMVSKIKREYLLWLKNVNKFVDG
What are the official names of this protein?
Uncharacterized protein At2g39790, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the MAM33 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: KCY_RHIME
Sequence: MTFVIAIDGPAAAGKGTLSRRIAEQYGFHHLDTGLTYRATAKALMDAGLPLDDEAVAEKTAREVDLSGLDRAVLSEHSIGEAASKIAVMPAVRRALVEAQRAFARKEPGTVLDGRDIGTVVCPDAAVKLYVTASPEVRAKRRHDEIVAGGGKADYTAIFEDVKKRDGRDMGRADSPLRPAEDAHLLDTSEMSIEAAFQAAKTLVDAALKEKI
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IMP4_ASHGO
Sequence: MLRRQARERREYLYRKAQELQESQLQQKRDLIKQALAQGKPLPKEVADDTKLQRDYQYDESAQESIDDEYSALSGIVDPKVIVTTSRDPSTRLSQFAKEVKLLFPTSVRLNRGNYIMKNLVDACQKSGTTDLVVLHEHRGVPTALTISHFPHGPTASFSLHNVVLRHDILNAGNQSEVHPHLIFDNFTTPLGQRVVKILKHMFPPGVKKDSPRVITFANRGDFISVRQHVYVKTRDGVELAEVGPRFEMKLYELTLGTLENKDADVEWQLRRFVRTANRKDYL
What is the function of this protein?
Component of the U3 small nucleolar ribonucleoprotein.  Required for the early cleavages at sites A0, A1 and A2 during 18S ribosomal pre-RNA processing (By similarity).
What are the official names of this protein?
U3 small nucleolar ribonucleoprotein protein IMP4, U3 snoRNP protein IMP4.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ARCC2_STAA3
Sequence: MKEKIVIALGGNAIQTTEATAEAQQTAIRCAMQNLKPLFDSPARIVISHGNGPQIGSLLIQQAKSNSDTTPAMPLDTCGAMSQGMIGYWLETEINRILTEMNSDRTVGTIVTRVEVDKDDPRFDNPTKPIGPFYTKEEVEELQKEQPDSVFKEDAGRGYRKVVASPLPQSILEHQLIRTLADGKNIVIACGGGGIPVIKKENTYEGVEAVIDKDFASEKLATLIEADTLMILTNVENVFINFNEPNQQQIDDIDVATLKKYAAQGKFVEGSMLPKIEAAIRFVESGENKKVIITNLEQAYEALIGNKGTHIHM
What are the official names of this protein?
Carbamate kinase 2.
What is the protein family that this protein belongs to?
Belongs to the carbamate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTC_BORA1
Sequence: MTLPTTQNGPLRHFLQFKDLTASEIGYVLDRARIIKDKFKRYEPHMPLHDRTLAMVFEKASTRTRVSFEAGMYQMGGSVINLTSNDSQLGRSEPIEDTARVVSRMVDIVMIRTFEQTRIERFAAHSRVPVINGLTNEYHPCQILADIFTYIEHRGSIAGRIVAWVGDANNMSYTWLQAAEMLGFTLHVSTPAGYQLDPARIGNPPPSVLKQFKDPMQACQGAHLVTTDVWTSMGYEAENEERRKAFADWCVDAEMMAAADPNAVFMHCLPAHRGEEVTGEVIDGPQSVVWDEAENRMHAQKALMEFLLLGEIH
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VL2_HPV82
Sequence: MVAARARRRKRASVTQLYSTCKAAGTCPPDVIPKVKGTTLADKILQWSGLGIFLGGLGIGTGSGTGGRTGYIPLGGGGRPGVVDIAPARPPIIIEPVAPTEPSIVNLVEDSSIINSGSTIPTFTGTDGFEITSSSTTTPAVLDITPSAGTVHVTSTNIENPLYIEPPFIEAPQSGEVSGHIFTSTPTSGTHGYEEIPMEVFASNVTTGKEPISSTPTPGVRRIAAPRLYSRAFSQVKVTNPDFISKPSTFVTFDNPAFEPADTSLSFEEPTDVAPDPDFLDIIKLHRPALTSRRGTVRFSRLGQKATIRTRSGKQIGARGHYYHDISSIAPAEELEMQPLLSPSTNNYSYDIYADLNEAETGFMQPTQTTPMLRSPFSPLSTQLPSLSSSVSSSYANVTIPFSTTYNVPIHTGPDVVLPTSPTVWPFIPHTSIDTQHAIVIQGGDYYFVAVYIFVTQTP
What is the function of this protein?
Minor protein of the capsid that localizes along the inner surface of the virion, within the central cavities beneath the L1 pentamers.  Plays a role in capsid stabilization through interaction with the major capsid protein L1.  Once the virion enters the host cell, L2 escorts the genomic DNA into the nucleus by promoting escape from the endosomal compartments and traffic through the host Golgi network.  Mechanistically, the C-terminus of L2 possesses a cell-penetrating peptide that protudes from the host endosome, interacts with host cytoplasmic retromer cargo and thereby mediates the capsid delivery to the host trans-Golgi network.  Plays a role through its interaction with host dynein in the intracellular microtubule-dependent transport of viral capsid toward the nucleus.  Mediates the viral genome import into the nucleus through binding to host importins.  Once within the nucleus, L2 localizes viral genomes to host PML bodies in order to activate early gene expression for establishment of infection.  Later on, promotes late gene expression by interacting with the viral E2 protein and by inhibiting its transcriptional activation functions.  During virion assembly, encapsidates the genome by direct interaction with the viral DNA.
What are the official names of this protein?
Minor capsid protein L2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L2 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host early endosome. Host Golgi apparatus.
Protein: CBK1_PNECA
Sequence: MQKVSGSGKKTTAFQQRKSDSVYNNNEMNKGTSSISYDPVYFVRDASSFTKTTHERAASVKLKLEHLYKVTVEQTVERNQRRMDFEAKLAQDRGSEERKKRQLNSLGQKESQFLRLRRTKLSLNDFHTVKVIGKGAFGEVRLVQKIDTGKIYAMKTLLKSEMFKKDQLAHVKAERDVLAESDSPWVVSLYYSFQDSQYLYLIMEFLPGGDLMTMLIKYDTFSEDVTRFYIAECILAIEAVHKLGFIHRDIKPDNILIDKTGHIKLSDFGLSMGFHKTHDNAYYQRLFESKINTSTSSTQNSLMVDTISLTMSSKDKIATWKKNRRIMAYSTVGTPDYIAPEIFTQHGYGQECDWWSLGAIMFECLIGWPPFCSENAHETYRKIINWRENLYFPEDLHLSAEAEDLIRKLLTSADQRLGRYGANDIKLHPFFRGVNWDTIREINAPFIPQLKSITDTSYFEEIDTIPNITMNSPPVLQNKIPSDVDQNLAFVGYTYKRFDMMTQKGIL
What is the function of this protein?
Protein kinase that seems to play a role in signaling pathways necessary for cell growth and mating.
What are the official names of this protein?
Serine/threonine-protein kinase CBK1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. COT1 subfamily.
Protein: COBQ_PROM0
Sequence: MELEAKLHEIKKPIMVLGTSSGAGKSLTVTAICRILKNLGEEPIPFKGQNMSNNAWVDWEGGEMAYSQALQAFACGINPAAEMNPILLKPQGNSISEVIHLGKSIGTTTAKNYYKDWFTPGWEVIKKSLKSIYEGNPNCRLIIEGAGSPVEMNLIHRDLTNLRVAKYLNANCILVTDIERGGVFAQIIGTLELMKPEEKKLIKGIIINRFRGDLSLFEDGKKWIENKTQIPVVGIIPWLNDSFPPEDSLDLIEKKSLSKNPEIKVGIIKLPSISNFSDFDPLENEETIFIEWIRKSQNLSKYDFIILPGSKQTIKDQIFLENSGLSKDIRDYSKNKGNIVGICGGLQMLGTTLEDPYFKEGSKNYSEQKIKGIGLLPLKTTFFKKKLTRQIKSKSIWPCQSEINGFEIHNGQTVLDEIQSSLKINPIFEDSDLGWYKENNKGGTIAGTYIHGIFENDSWREHYINLIRKSKNLPTLNKKSISYKEKRQFIIDNLANEFHKHLNLKSFLS
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: AARD_RAT
Sequence: MGLGDYSHCRQRMSRGLYGVSGRATLWSPAFHPVHRMPCGTWRIEAPEHVRASSPVLEHLRRQLERAFQRAAARGRARRAREAVAAVAAAAAAAREERSRARMECALARLRAELLELRFQNHQLARTLLDLNMKMQQLKKRQDQERASKPQSPQDEEMNPECGNA
What are the official names of this protein?
Alanine and arginine-rich domain-containing protein, rA5D3.
Protein: FOLD_AGRFC
Sequence: MAVVIDGKAKAASVTEAVRKSAEALEAEKGVKPGLAVVIVGNDPASHAYVNSKSKMAKQCGFNSIQHTLPEETTQAALLKLVGELNTDASIHGILVQLPLPKHFNSDEIIQSILPEKDVDGLSVLNAGKLATGDLATGLISCTPAGAMLLVRGIHGDDLSGLNAVVIGRSNLFGKPMGQLLLNANATVTMAHSRTKDLVTVCKTADILVAAVGRAAMVKGDWVKPGATVIDVGINRIAAPEKGEGKSKLVGDVAFDEASAVAAAITPVPGGVGPMTIAMLMANTVIAAHRALGKTAPKF
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: TYSY_PECAS
Sequence: MKQYLDLMKKVLEEGTPKADRTGTGTRSIFGHQMRFNLQDGFPLVTTKKCHLRSIIHELLWFLNGDTNVAYLNENKVSIWDEWADENGDLGPVYGKQWRSWGAADGRQIDQLKNVLTQLRQDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLSCQLYQRSCDIFLGLPFNIASYALLVHMVAQQCDLDVGDFVWTGGDTHLYNNHMEQTHLQLSREPRALPKLVIKRRPDTLFDYRFEDFEIEGYDPHPAIKAPVAI
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.