PharMolix/UniProtQA huggingface dataset:
Protein: PYRH_STRT1
Sequence: MAEPKYKRVLIKLSGEALAGEKGVGIDLPTVQAIAKEIAEVADSGIQIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTTMNALVMADSLKQLGVDTRVQTAIDMKSVAEPYIRGRALRHFEKGRIVIFAAGIGSPYFSTDTTAALRAAEIESDAILMAKNGVDGVYNDDPRKNADAVKFDKLTHVEVIKRGLKIMDATASTLSMDNDIDLVVFNMNEPGNIKRVIFGEQIGTTVSNKAELRK
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2507_LACPL
Sequence: MESRSILETIQMVAEENLDIRTITMGISLFDCVDSDGERARQKIYDKITTSAKDLVKVAAQIQEEYGIPIINKRIAVTPIALIAAASQDQDYVAYAVTMERAAQALGVDLIGGFSALVQKGYQSGDRKLIASIPAALAATSRVCSSVNVGSTRAGINLDAVGEMGRIIKQIAADDPVNCMSLVVFANAVDDNPFMAGAFHGVGEADRVINVGISGPGVVKRALEEVRGQSIDIVSEQIKKTAFKVTRMGQFVGSIASERLHVPFGIVDLSLAPTPNEGDSVAEILEEIGLESVGAPGTTAALALLNDAVKKGGVMACEHVGGLSGAFIPVSEDAEMIRAVSAGRLNIEKLEAMTAVCSVGLDMIAVPGDTSAATISGMIADEAAIGMINNKTTAVRVIPATGKGVGDAVEFGGLFGQAPVMPVNTNQPTTFIKRGGHIPAPIHSFKN
What are the official names of this protein?
UPF0210 protein lp_2507.
What is the protein family that this protein belongs to?
Belongs to the UPF0210 family.
Protein: HFLD_SODGM
Sequence: MAKNYFDITLALAGVCQSARLVQQLAHQSQCDEPPLRVSLQSLLDLNPPSVRAVYGDNPANLRMGLETLQNVLNASSREGLGAELTWYTLGLIVLERKLNGNRGAQAELSRRIDALDRQLSHFDLLSDTLISAMASIYVDIISPLGPRIQVTGAPVVLQNTQIQAKVRAVLLAGIRSAVLWQQVGGGRFQLMFARNRLFKKAKQILSHT
What are the official names of this protein?
High frequency lysogenization protein HflD homolog.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HTPG_SHESH
Sequence: MSQQETHGFQTEVKQLLNLMIHSLYSNKEIFLRELVSNAADASDKLRYEALTNDALYEGDGELRVRISTNKEKGTVTIEDNGIGMTRDTVIEHLGTIAKSGTADFFKNLSGDESKDSQLIGQFGVGFYSSFIVADKVTVRTRAAGHGSDEGVQWESAGEGDFTVDTIVKETRGTEIVLHLREEEKEFADDYRLRSIITKYSDHISVPVEMWEEGTPAIEATEEQEAVAATDGQWQSMNKATALWTRNKSDVSKEEYEEFYKHISHDFTDPLLWSHNRVEGKQEYTSLLYIPSKAPWDMWNRDRKHGLKLFVQRVFVMDDAEQFMPSYLRFVQGLIDSNDLPLNVSREILQDNKVTTALRTAVTKRVLGMLEKLAKNDAEKYQTFWAEFGQVLKEGPAEDMVNKERIAGLLRFASTHTEDAAPTVSLADYVSRMQEGQSKIYYIVADSHEAAANSPHLELLRKKGIEVVLMSERIDEWLINHLTDFDGKQLHSVTRGDLELGDLEDAGEKEAQEKLETESEGLVKRIKDSLGEKVSAVKVTTRLTDTPACVVAGEGEMSTQMIKLMEAAGQAVPESKPTFEINPEHPLVARLNDEQDEALFAQWSDLLLQQAQLSEKGSLADPSAFIKLMNEMLLAKLK
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR9_BACAA
Sequence: MKKRALVSVSDKTGVVEFVKGLLEQGIEVISTGGTKKLLEENGLQVIGISEVTGFPEIMDGRVKTLHPNIHGGLLAVRDNETHVAQMNELGMEPIDFVVVNLYPFKETIAKPDVTFADAIENIDIGGPTMIRSAAKNHKFVSVIVDPVDYDVVLAELKENGEVAEETKRKLAAKVFRHTAAYDALISNYLTEQMGEESPETLTVTFEKKQDLRYGENPHQKATFYKAPFAATSSVAYAEQLHGKELSYNNINDADAALSIVKEFTEPAVVAVKHMNPCGVGVGTDIHEAYTRAYEADPVSIFGGIIAANREIDKATAEKLHEIFLEIIIAPSFSKEALEVLQSKKNLRLLTVNIEKATSASKKLTSVQGGLLVQEEDTLSLDESTISIPTKREPSEQEWKDLKLAWKVVKHVKSNAIVLAKDDMTIGVGAGQMNRVGSAKIAITQAGEKAQGSALASDAFFPMPDTVEEAAKAGITAIIQPGGSIRDEDSIKVADTYGIAMVFTGVRHFKH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: PDXH_BURMA
Sequence: MTTLADLRTNYSRASLDAADVNPNPFVQFDVWFKEALDAQLPEPNTMTLATVDESGRPSARIVLIKGADERGFVFFTNYESRKGRELAHNPNAALLFYWIELERQVRVEGRIEKTSEEESDRYFASRPLGSRIGAWASEQSAVIESRALLEAREKEIGARFGENPPRPPHWGGYRLVPSSIEFWQGRPSRLHDRLLYTRDAASASGWKITRLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: RPOZ_MYCS2
Sequence: MSTPHADAQLNAADDLGIDSSAASAYDTPLGITNPPIDELLSRASSKYALVIYAAKRARQINDYYNQLGDGILEYVGPLVEPGLQEKPLSIALREIHGDLLEHTEGE
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: ROA2_SAGOE
Sequence: MEREKEQFRKLFIGGLSFQTTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVTFSSMAEVDAAMAARPHSIDGRVVEPKRAVAREESGKPGAHVTVKKLFVGGIKEDTEEHHLRDYFAEYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSRQEMQEVQSSRSGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNGYGGGPGGGNFGGSPGYGGGRGGYGGGGPGYGNQGGGYGGGYDNYGGGNYGSGNYNDFGNYNQQPSNYGPMKSGNFGGSRNMGGPYGGGNYGPGGSGGSGGYGGRSRY
What is the function of this protein?
Heterogeneous nuclear ribonucleoprotein (hnRNP) that associates with nascent pre-mRNAs, packaging them into hnRNP particles.  The hnRNP particle arrangement on nascent hnRNA is non-random and sequence-dependent and serves to condense and stabilize the transcripts and minimize tangling and knotting.  Packaging plays a role in various processes such as transcription, pre-mRNA processing, RNA nuclear export, subcellular location, mRNA translation and stability of mature mRNAs.  Forms hnRNP particles with at least 20 other different hnRNP and heterogeneous nuclear RNA in the nucleus.  Involved in transport of specific mRNAs to the cytoplasm in oligodendrocytes and neurons: acts by specifically recognizing and binding the A2RE (21 nucleotide hnRNP A2 response element) or the A2RE11 (derivative 11 nucleotide oligonucleotide) sequence motifs present on some mRNAs, and promotes their transport to the cytoplasm (By similarity).  Specifically binds single-stranded telomeric DNA sequences, protecting telomeric DNA repeat against endonuclease digestion (By similarity).  Also binds other RNA molecules, such as primary miRNA (pri-miRNAs): acts as a nuclear 'reader' of the N6-methyladenosine (m6A) mark by specifically recognizing and binding a subset of nuclear m6A-containing pri-miRNAs.  Binding to m6A-containing pri-miRNAs promotes pri-miRNA processing by enhancing binding of DGCR8 to pri-miRNA transcripts.  Involved in miRNA sorting into exosomes following sumoylation, possibly by binding (m6A)-containing pre-miRNAs.  Acts as a regulator of efficiency of mRNA splicing, possibly by binding to m6A-containing pre-mRNAs (By similarity).  Plays a role in the splicing of pyruvate kinase PKM by binding repressively to sequences flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform (By similarity).
What are the official names of this protein?
Heterogeneous nuclear ribonucleoproteins A2/B1, hnRNP A2/B1, Vitamin D response element-binding protein 2, VDRE-BP 2.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Cytoplasmic granule. Secreted, extracellular exosome. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Component of ribonucleosomes. Not found in the nucleolus. Found in exosomes follwong sumoylation.
Protein: PSBK_RIPO1
Sequence: MEAALLLAKLPEAYQIFDPLVDVLPIIPLFFLALAFVWQAAVGFK
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein K, PSII-K.
What is the protein family that this protein belongs to?
Belongs to the PsbK family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: QCR72_ARATH
Sequence: MASFLQRLVDPRKNFLARMHMKSVSNRLRRYGLRYDDLYDPLYDLDIKEALNRLPREIVDARNQRLMRAMDLSMKHEYLPDNLQAVQTPFRSYLQDMLALVKRERAEREALGALPLYQRTIP
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol.  In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
What are the official names of this protein?
Cytochrome b-c1 complex subunit 7-2, mitochondrial, Complex III subunit 7-2, Complex III subunit VII, Ubiquinol-cytochrome c oxidoreductase subunit 7-2.
What is the protein family that this protein belongs to?
Belongs to the UQCRB/QCR7 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: TF2B2_THEVO
Sequence: MPYSDKMAIESEAPKRCPECHSEHLIRDYEHGELICADCGAVIEDSFIDQGPEWRAFDSDQDERRARTGSPMTYLSHDKGLATEISWSNKDYYGKRIPHKNRAQIYRVRKWHQRIRVSNAAERNLSLALQLLNDIGAKLGIPKDIKETSALIYRKAVEKNLIRGRSIESIVCASIYAACRKVNIPRTLDEIAKASEVNKKKIGKAYRHLAKELDLNLRPTTPFSYIAQFCNKLDLDKQAIVISEDIVRQAMSMGISSGKGPTGIAAAAIYIASVKVGKPRTQKEIARISGVTEVTIRNRYKEISKALNISISE
What is the function of this protein?
Stabilizes TBP binding to an archaeal box-A promoter.  Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
What are the official names of this protein?
Transcription initiation factor IIB 2, TFIIB 2.
What is the protein family that this protein belongs to?
Belongs to the TFIIB family.
Protein: MIAA_YERP3
Sequence: MNDIENLDRPPAIFIMGPTASGKTALSIALRQRLPVELVSVDSALIYRGMDIGTAKPSAQELALAPHRLIDIRDPAESYSAADFRKDALKEMADITAAGRIPLLVGGTMLYFKALLDGLSPLPSADPQVRQRIEQQASELGWGALHQQLAVIDPVAAARIHPNDPQRLSRALEVFFISGKTLTELTKISGETLPYRVHQFAIAPASRELLHQRIELRFHQMLDAGFEAEARVLFDRGDLHTDLPAIRCVGYRQMWSYLSGEIDYNDMVYRGVCATRQLAKRQMTWLRGWSSVQWLDSDKPGEALDSVIQVVSA
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: BYE1_YEAST
Sequence: MSVRTSSRSNKGQNKYIEYLLQEETEAPKKKRTKKKVDSAIEKNKKSDSSQEPRKDTENVRTDEVDEADEGYVRCLCGANNENYDAAEYSHGDMVQCDGCDTWQHIKCMTDGKDTIDGLMSEDSKYYCELCDPSLYAHLETSKEAEVSEDEDYHDDVYKPVNDHDDNDADVFLDEESPRKRKRSPDSAKGIHIKSKQVKKSNGSKKRNKSIDAAKSDTAENEMPTRKDFESEKEHKLRYNAEKMFSTLFSKFIVPETIEAKLYELPDGKDVISISQEFAHNLEEELYKACLNVEFGTLDKIYTEKVRSLYSNLKDKKNLELKAHVVEGKLPLNKLVNMNASELANPDLQEFKEKRDKIILENFIVEVPDKPMYVKTHKGDELIEDIAEPQEDILYSKDSIRLHNIDSIDSDKSKIEQTHAISKEPSPSTIINEESLNCAFLYPGLGLEFTGYLNYIGASQKLRRDIFKEAIGDGKLYVEGRLPTTTAAPYLKEISCSRAILVYQLFPSNDSESKTTFADVVDSLENKGRIAGIKPKTRYEKDFYIVPSKGGEIPEILKDILGSHNDERSERFSRMKSDERTLFAFVVVKQEFIH
What is the function of this protein?
Negative regulator of transcription elongation.
What are the official names of this protein?
Transcription factor BYE1, Bypass of ESS1 protein 1.
What is the protein family that this protein belongs to?
Belongs to the BYE1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TAAR9_RAT
Sequence: MELCYENVNGSCIKSSYSPWPRAILYAVLGLGALLAVFGNLLVITAILHFKQLHTPTNFLVASLACADFLVGVTVMPFSTVRSVEGCWYFGDTYCKFHTCFDTSFCFASLFHLCCISIDRYVAVTDPLTYPTKFTISVSGVCIALSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFLLFFLPTVVMVFLYGRIFLVAKQQARKIEGSANQPQASSESYKERVARRERKAAKTLGIAMAAFLVSWLPYIIDAVIDAYMNFITPAYVYEILVWCVYYNSAMNPLIYAFFYPWFRKAIKLIVSGKVFRADSSRTNLFSEEAGAG
What is the function of this protein?
Orphan receptor.  Could be a receptor for trace amines.  Trace amines are biogenic amines present in very low levels in mammalian tissues.  Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative.  Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood.
What are the official names of this protein?
Trace amine-associated receptor 9, TaR-9, Trace amine receptor 9, Trace amine receptor 3, TaR-3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CLPS_ECOLC
Sequence: MGKTNDWLDFDQLAEEKVRDALKPPSMYKVILVNDDYTPMEFVIDVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCTLEKA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: CDPAS_METLZ
Sequence: MIPAYIPNPAAALLGGGTPVDFGKCAKDGRRILGDGKTWRGLIGGIVVGIIFGLMQIFLYNYFNLEFLPKQTIITVCALATGALLGDMVKSYFKRRLGKDRGAKWPIADMYDMVVGSLVLMTLALLVTGNLNWFTENFDSVGFLIATIIAILILSPLLHRGTNIIGYLLGLKDVPW
What is the function of this protein?
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP.  This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
CDP-archaeol synthase, CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-archaeol synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NUDL_ECOLU
Sequence: MEYRSLTLDDFLSRFQLLRPQINRETLNHRQAAVLIPIVRRPQPGLLLTQRSIHLRKHAGQVAFPGGAVDDTDASVIAAALREAEEEVAIPPSAVEVIGVLPPVDSVTGYQVTPVVGIIPPDLPYRASEDEVSAVFEMPLAQALHLGRYHPLDIYRRGDSHRVWLSWYEQYFVWGMTAGIIRELALQIGVKP
What is the function of this protein?
Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.
What are the official names of this protein?
Uncharacterized Nudix hydrolase NudL.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. PCD1 subfamily.
Protein: CDS2_CONLT
Sequence: MPKLEMMLLVLLILPLCYIDAVGPPPPWNMEDEIIEHWQKLHCHEISDPTPWILCSPEPLCGGKGCCAQEVCDCSGPVCTCPPCL
What is the function of this protein?
Probable neurotoxin.
What are the official names of this protein?
Conotoxin Lt28.2, Conotoxin Lt15.3.
What is the protein family that this protein belongs to?
Belongs to the conotoxin D superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: XYNC_BACIU
Sequence: MMSSVKKTICVLLVCFTMMSVMLLGPGVTEVSAASDAKVNISADRQVIRGFGGMNHPAWIGDLTAAQRETAFGNGQNQLGFSVLRIHVDENRNNWYKEVETAKSAIKHGAIVFASPWNPPNDMVETFNHNGDTSAKRLRYDKYAAYAQHLNDFVNFMKSNGVNLYAISMQNEPDYAHEWTWWTPQEILRFMRENAGSINARVIAPESFQYLKNISDPILNDPQALRNMDILGTHLYGTQVSQFPYPLFKQKGGGKELWMTEVYYPNSDNNSADRWPEALGVSEHIHHSMVEGDFQAYVWWYIRRSYGPMKEDGMISKRGYNMAHFSKFVRPGYVRIDATKNPEPNVYVSAYKGDNKVVIVAINKNNTGVNQNFVLQNGTASQVSRWITSSSSNLQPGTDLKVTDNHFWAHLPAQSVTTFVVKR
What is the function of this protein?
Catalyzes the depolymerization of methylglucuronoxylan (MeGAXn).  It cleaves the beta-1,4-xylosidic bond penultimate to that linking carbon one of the xylose residue substituted with alpha-1,2-linked 4-O-methyl-D-glucuronate (MeGA) (By similarity).
What are the official names of this protein?
Glucuronoxylanase XynC, Endoxylanase XynC, Glucuronoxylan xylanohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 30 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RB22A_HUMAN
Sequence: MALRELKVCLLGDTGVGKSSIVWRFVEDSFDPNINPTIGASFMTKTVQYQNELHKFLIWDTAGQERFRALAPMYYRGSAAAIIVYDITKEETFSTLKNWVKELRQHGPPNIVVAIAGNKCDLIDVREVMERDAKDYADSIHAIFVETSAKNAININELFIEISRRIPSTDANLPSGGKGFKLRRQPSEPKRSCC
What is the function of this protein?
Plays a role in endocytosis and intracellular protein transport.  Mediates trafficking of TF from early endosomes to recycling endosomes (PubMed:16537905).  Required for NGF-mediated endocytosis of NTRK1, and subsequent neurite outgrowth (PubMed:21849477).  Binds GTP and GDP and has low GTPase activity.  Alternates between a GTP-bound active form and a GDP-bound inactive form (PubMed:16537905).
What are the official names of this protein?
Ras-related protein Rab-22A, Rab-22.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Endosome membrane; Lipid-anchor. Cell membrane; Lipid-anchor. Early endosome. Late endosome. Cell projection, ruffle. Cytoplasmic vesicle. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Note=Recruited to phagosomes containing S.aureus or M.tuberculosis.
Protein: SYA_NOSP7
Sequence: MSSNPQYLSGNEIRNTFLNFFAQRSHQILPSASLVPEDPTVLLTIAGMLPFKPIFLGQRTPEFKRATTSQKCIRTNDIENVGRTKRHHTFFEMLGNFSFGDYFKEQAIAWGWEISTQVFGFSPQNLVVSVFEDDDEAFAIWRDQIGVPVARIKRLGEDDNFWVSGPTGPCGPCSEIYYDFHPERGDENIDLEDDSRFIEFYNLVFMQYNRDVLGNLTPLQNKNIDTGMGLERMAQILQKVPNNYETDLIFPIIQTAAQIAGIDYHSSDEKTKVSLKVIGDHVRSVVHMIADEIRASNVGRGYVLRRLIRRVVRHGRLIGISGEFTTQVAESAIALSESAYPNVRQREAAIKAELQREESNFLRTLDRGEKLLEEIIQEVKQQGSTQISGESAFTLYDTYGFPLELTQEVAEENNLTVDAEGFEAQMEIQKGRGRDAHETIDLTVQGSLDKLAEHIQVTEFLGYTQSAATAIIEAILLEGVSQEEAEAGTQVQIVLDKTPFYAESGGQIGDRGYISGDGIVVRVEDVKKESDFFVHFGRIERGTLRVGDRVTAQIDPACRRRAQANHTATHLLQAALKKIVDDGISQAGSLVSFDRLRFDFNCPRALTAEEVQQVEEQVNSWIAEAHAAKVEVLPLAEAKAKGAVAMFGEKYGDEVRVIDFPNVSMELCGGTHVSNTAEIGVFKIISEAGVASGVRRIEAVSGPAILDYLNLRDKVVKDLSDRFKVKPEELPDRITSLQSELRNSQKELETLKVQLAIAKSDSLLQTAETVGDHKIIVAQLENVDPESLKTAAERLLQKIGNGAVVLGSVPEADKVSIVAAFSPEVNKKGLQAGKFVGAIAKICGGGGGGRPNLAQAGGRDASKLPDALGQAESDLKSALA
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RT109_SCHPO
Sequence: MPDLWSESILEGRKLSIYHLKSTLEKCPFLFGQSKKSKDFQFGSHLFLVEEQNVFIFGMECIVYEKNKEFIVFVSKADSTGFGSKGVSCNSLAFCCLVTLIDGLRKQGAENVTLTLFAIAQGQYLFPESVDNGQKHVLNDSGLLRWWVNCLEKLRKYYTDSEAPNDSEKQKNSTLLPKAYLFVPGLENIRSYLPNRHWIESNAITTGKAVEELPRFPDDPKCRYLCELQDEKSDMSVEEFWDTLTYRQECSSGKLVGFFTLQLQFYQTREFIAKDNFGDSGVMIPAKLYRVTYDTLLKHPFGSLSDAQSSTEKFLSNTLSAVQNLKDFHYKRYKLDICGLAKRDDRKNHNHSKPATQANILQPRKKVKK
What is the function of this protein?
Histone chaperone-dependent acetylase that modifies 'Lys-56' of histone H3 (H3K56ac), which occurs predominantly in newly synthesized H3 molecule during G1, S-phase and G2/M of cell cycle (PubMed:17369611, PubMed:17690098, PubMed:20656950).  Histone H3 'Lys-56' acetylation is required for S-phase-linked DNA damage tolerance and proper silencing in pericentromeric heterochromatin (PubMed:17369611).
What are the official names of this protein?
Histone acetyltransferase rtt109.
What is the protein family that this protein belongs to?
Belongs to the RTT109 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DDL_JANMA
Sequence: MKKEFGKVGVLFGGRSAEREVSLMSGKGVLAALLSKGIDAHPFDPAERSLAELAAEKFDRVFIALHGRFGEDGSLQGALEQLGIPYTGPGVMASAIAMDKVITKRVCLSHGVPTPKFTALEVEATTAEQLQAIAAEFGMPLMLKAPHEGSTIGIAKVETAEGMQAGFDLCAKYDDVVLVEQFVKGRELTVPVLGSGRNARALPIVEIIAPQGNYDYEHKYFSDDTQYLCPAPFDAAFTKRVQALAVSAFNAVGCTGWARVDFLVRESDNEPFLLEINTSPGMTGHSLVPMSAKVAGTAYEDLCVEILRMAKLGLKPVQHK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPOE_CRYNB
Sequence: MPSRGSFRGRGRGSGSGFGSNTRFTGRRRGRGGGGGGGGVAYGIDRRPATSTNQANREDGTAATEKFEEVKVYDEIDEKIGFWRFESVRAEGEEKVGWLVNMHQTLVPSDVHPGGLAAVDYYFIQDDGGSFKVSIPYEPYFYLTCRGGTESIVEEWLLKRYEGIIIRIEREKKWDLSLPNHLLSAPPVFLKLFFHNTADLQTIRRDLLPLARSNSEKFTAVDAYADVVSAEAAANGHGDDENRAWGAEDDTKKKKDKEPSECIIEVREHDLAYHLRVAIDLNIRVGLWYTVTSRTGVITLERIPDRVKRADPVVMAYDIETTKQPLKFPDQQTDQIMMISYMIDGMGYLITNREIVGEDIDDFEYTPKDEYPGEFTVFNEPDEPAVIRRWFEHIRDSKPTVIATYNGDSFDFPFVDARAKIHGISMYEEIGFKPDIEEEYKSRSTMHMDCFRWVKRDSYLPQGSQGLKAVTTAKLGYNPIELDPELMTPYAIEQPQILAQYSVSDAVATYYLYMKYVHPFIFSLCNIIPLSPDEVLRKGTGTLCETLLMVEAYDAHIIMPNRHEDPHGVTYEGHLLASETYVGGHVEALEAGVFRSDIPTHFKIVPSAIQELIDDLDAALRFSLIEEGQVKLEDVENYDEVKQQIQTALETMRDEPNRFDNPLIYHLDVAAMYPNIMLSNRLQPDSVKEEADCAVCDYNRPDKKCDRRMEWAWRGEYFPAKRDEVNMVRYALEQETFPPKRPYDPKRRFVDLTPTEQSALLHKRLGDYSRKVYKKTHDTKIVTKTTIICQRENSFYIDTVRAFRDRRYEYKGLHKTWKKNLDKAFEEGGAVATVDEAKKMIVLYDSLQLAHKCILNSFYGYVMRKGARWYSMEMAGITCLTGATIIQMARQLVEQIGRPLELDTDGIWCMLPGVFPEDFNFKLKNGKKFGISYPCTMLNHLVHAQFTNDQYHELVNNDSGTYNVKKENSIFFELDGPYKAMILPSSKEEDKLLKKRYAVFNPDGSLAELKGFEVKRRGELQMIKIFQSQIFDKFLLGKTTEECYAAVATVADQWLDILQSKASSLHDDELVDLIAENRSMSKTLAEYAGQKSTSISTARRLAEFLGEQMVKDKGLSCRFIISAKPNGAPVTERAVPVAIFTAEEPVKRHYLRKWLKDNSLTDFDLRTILDWDYYTERLGSVIQKLITIPAALQKVPNPVPRIRHPDWLYKRIATKEDKFQQHKITDMFTKLKDMEDLGDGQKKVGPKLAVVRRRNRKEQEKESEVEEVPPEPEYDYAGYIRIMKKKWRKQRQEKARARKSGLRQDGTISSMLRTQTSSMNSKQWDVIQIASTNRPGEFKLWLAIDGTFQSVRLKVPREFYLNFKEDPEPQMLATDRYEAVEVVRTLPRGQPARHLYKLSVDEVLFMEGESHFSTLINNPNVDGAFELQVPLVVRALLSLGTSCALRSNILGGLNRGLDKGFDLVDLERSGNLSRRKYLNEGRGIRYHFLFHAVADQRHIIGLFSPDSTNASIYLVDRAKNRQQLPNPLKFYTDRVERAERGVFSYPDMLDFTTSYHSSESSAFKALGKDLQAINHGLNVIALCSPFEHSYYQAKAPVYSNFPFITYRLGKEEDPGLMWLLQTSRRMIGLYLRLSSWLKEQIQIASHFDVPIGNLGADIAVFLADIEFARRLKQQDMLIWWSSTPRPDLGGSEEDANSSEDLVSPHISNRGCYSSTVLEMEVSDLAINAVLQSALVNEMEGSGTGSLAFDSASHNLDEYAKGAVNTSVMLGDAVLSTQTFGVLKSMLRAWYADKARAHVKGDSLSPAEIVVDQFWRWISSSTSSMFEPALHRFLHGLMRKTFLQLLAEFKRLGTQVVYADFGRVFLLTSKPDAGSAFAFAKYLVAAANSQELFRHLIIDVAQFWNYLAWMDVANFGGVKVSPETAASREPPAKRFEISMDWNIQSFLPGTLQPVFERNVASFIFSLYSAKRSSSDGREPLRVIHSLNIDQPGTEATSTMNPTKEKEKKAASKSISQTLTRRLLSDIAAVKRQQAAVHLEPEEAYTLAFPDLPGARSKRINPTLELIKAITEVYSLASEHSIEVQILKRNLLDLIGVKEFSSDAAFNPPCESIEVPMVICKKCNAIRDVDLCRDPDRLPSVNPDSGEMLEPARKNWVCHKCDSEYDRFQIEQPLIEMVTKTITNYQIQDVICLKCSQTKSDNLAATCKCGGGFRTTSNRNELKTKLKMIKSVCDYHKLPFAGSYVEETLSRW
What is the function of this protein?
DNA polymerase II participates in chromosomal DNA replication.
What are the official names of this protein?
DNA polymerase epsilon catalytic subunit A, DNA polymerase II subunit A.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Nucleus.