PharMolix/UniProtQA huggingface dataset:
Protein: ENO_SALHS
Sequence: MSKIVKVIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVGAVNGPIAQAILGKDAKDQAGIDKIMIDLDGTENKSNFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKGKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RS17_SHEB5
Sequence: MSDKIRTLQGRVTSNKMDKSITVAIERQVKHPIYGKYIKRTTKIHAHDETNQCNEGDLVAIRECRPLSKTKSWTLVEVVSKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: RL332_STAA8
Sequence: MRVNVTLACTECGDRNYITTKNKRNNPERVEMKKFCSRENKQTLHRETK
What are the official names of this protein?
50S ribosomal protein L33 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: HSLU_PSELT
Sequence: MTNFDNLTPKEIVRELDKYIIGQYQAKKAVAIAIRNRIRRQKLPDIWQKEVLPKNILMIGPTGVGKTEIARRLAQLSGSPFLKVEATRFTEVGYVGKNVDSMVRDLVEISVNMVKKERMEQVKDKAEQMVEERILDALIPESRKPQNISFMGLFTASQQQQPSPEERRSLRQKREEIRQKLRNGELENEMIEIEIEKEISPFIGALGQGELEDLGIDLGSMLGSLMPKTRQKKRMTVSEARRTLLPIESEKLIDMDKATQEALERAQNRGIIFIDELDKIAVKSSGSGPDVSRQGVQRDLLPIVEGTTIMTKYGPVRTDYILFIGSGAFHMSRPSDLIPELQGRFPIRVELSSLTRKDFVRILVEPENAITKQYQALLSTEGIELIFTEDGIEEMAKIAYELNQRLENIGARRLYTVVEKVLEEISFEAPDVQEKKIIIDAKYVMGKLENIISDEDVSSYIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMA_BACAA
Sequence: MKWSEISIHTTEEAVEAVSHILHEAGASGVAIEDPAELTKEREQQYGEIYALNPDEYPAEGVLIKAYFPQTDSLHETIAGVKSSIDVLPSYDIEIGTGNITVNEVNEEDWATAWKKYYHPVQISDTFTIVPTWEEYTPSSPEEKIIELDPGMAFGTGTHPTTTMCIRALEKTVQPGDTIIDVGTGSGVLSIAAAKLGASSVQAYDLDPVAVESAEMNVRLNKTDDVVSVGQNSLLEGIEGPVDLIVANLLAEIILLFPEDAARVVKSGGLFITSGIIAAKEKVISEALEKAGFTIEEVLRMEDWVAIIARNA
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMFO_STRSV
Sequence: MSSSYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKSTPQHKTADFAELVCSNSLRGDALTNAVGLLKEEMRRLDSVILKSAEATRVPAGGALAVDREGFSQMVTELVTNHPLIEVIREEITEIPEDAITVIATGPLTSDALAEKIHALNGGDGFYFYDAAAPIIDVNTIDMTKVYLKSRYDKGEAAYLNAPMTKQEFMDFHDALVNAEEAPLNSFEKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYQGPRDGEYKTPYAVVQLRQDNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQTFRSKKLPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKGEEALVFPETTAIGSLPHYVTHADSKHFQPMNVNFGIIKELDGPRIRDKKERYEKIAERALQDLQPYLDK
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4TF_SINFN
Sequence: MRTRRVYLPLKGELSMDWHDYLGPLGRGAWVTIQFTLYSMFFGAVCSFAFGIGKLSKNPFVKGFSILYIEIFRGTSLLVQLFWLFFALPIAGDMMGIDLRLSPVVAGVLALSLNLGAYGAEIVRGAIQAVSPSQYEAATALNFSSSQALWRVALPQAIPEMMPSFSNLAIAALKDTSLVSLITLHDLTFAAEQLRNFYQDSTTVYTMVLLMYFGIALVLSFFMRLIESSVTRWRGHRR
What is the function of this protein?
Probably part of the binding-protein-dependent transport system y4tEFGH for an amino acid.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Probable amino-acid ABC transporter permease protein y4tF.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS20_RAT
Sequence: MAFKDTGKTPVEPEVAIHRIRITLTSRNVKSLEKVCADLIRGAKEKNLKVKGPVRMPTKTLRITTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADA
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
40S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSH1_ECO27
Sequence: MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGHPEALGSALTHKWITTDFAEALLEFITPVDGDIEHMLTFMRDLHRYTARNMGDERMWPLSMPCYIAEGQDIELAQYGTSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFWQAKCGDISGADAKEKISAGYFRVIRNYYRFGWVIPYLFGASPAICSSFLQGKPTSLPFEKTECGMYYLPYATSLRLSDLGYTNKSQSNLGITFNDLYEYVAGLKQAIKTPSEEYAKIGIEKDGKRLQINSNVLQIENELYAPIRPKRVTRSGESPSDALLRGGIEYIEVRSLDINPFSPIGVDEQQVRFLDLFMVWCALADAPEMSSKELACTRVNWNRVILEGRKPGLTLGIGCETAQFPLPQVGKDLFRDLKRVAQTLDSINGGEAYQKVCDELVACFDNPDLTFSARILRSMIDTGIGGTGKAFAEAYRNLLREEPLEILREEDFVAEREASERRQQEMEAADTEPFAVWLEKHA
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
Protein: BETA_ECOL6
Sequence: MQFDYIIIGAGSAGNVLATRLTEDPNTTVLLLEAGGPDYRFDFRTQMPAALAFPLQGKRYNWAYETEPEPFMNNRRMECGRGKGLGGSSLINGMCYIRGNALDLDNWAQEPSLENWSYLDCLPYYRKAETRDVGENDYHGGDGPVSVTTSKPGVNPLFEAMIEAGMQAGYPRTDDLNGYQQEGFGPMDRTVTPHGRRASTARGYLDQAKSRPNLTIRTHAMTDHIIFDGKRAVGVEWLEGDSTIPTRAAANKEVLLCAGAIASPQILQRSGVGNAELLAEFDIPLVHELPGVGENLQDHLEMYLQYECKEPVSLYPALQWWNQPRIGAEWLFGGTGVGASNHFEAGGFIRSREEFAWPNIQYHFLPVAINYNGSNAVKEHGFQCHVGSMRSPSRGHVRIKSRDPHQHPGILFNYMSHEQDWQEFRDAIRITREIMHQPALDQYRGREISPGVECQTDEQLDEFVRNHAETAFHPCGTCKMGYDEMAVVDGEGRVHGLEGLRVVDASIMPQIITGNLNATTIMIGEKIADMIRGKEALPRSTAGYFVANGMPVRAKK
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
What are the official names of this protein?
Oxygen-dependent choline dehydrogenase, CDH, CHD, Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: NUOI_JANSC
Sequence: MTQIDYTRAAKYFLLADFFKGFKLGMKYFFAPKVTINYPHEKGPLSPRFRGEHALRRYPNGEERCIACKLCEAICPAQAITIDAEPREDGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFATETREELYYDKEKLLANGERWESAIAHNLELDAPYR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: YCF2_DAUCA
Sequence: MKGHQFKFWIFELREILREIKNSHYFLDSWTQFNSVGSFIHIFFHQEHFIKLFDPRIWSILLSRNSQGSTSNRYFTIKGVVILFVVAVLIYRINSRNMVERKNLYLIGLLPIPMNSIGPRNDTLEESVGSSNINRLIVSLLYLPKGKKISESCFLNPKESTWVLPITKKCSMPESNWGSRWWRNWIGKKRDSSQLKGSSDQSRDPLDSISNEDSEYHTLINQRKIQQLKERSILWDPSFLQTERTEIESDRFPKSLSGYSSMSRLFTEREKQVINHLLPEEIEEFLGNPTRSVRSFFSDRWSELHLGSNPTERSTRDHKLLKKQQDLSFVPSRRSEKKEMVNIFKIITYLQNTVSIHPISSYPGCDMVPKDEPDMDSSNKISFLNKNPFLDLFHLFHDRNMGGYTLHHDFESEERFQEMADLFTLSITEPDLVYHKGFAFSIDSYGLDQKQFLNEVFNSRDESKKKSLLALPPFFYEENESFYRRIIKKWVRISCGNDLEDPKPKKMVFASNNLNVLNRFFLMNRSDRNFEYGIQRDQIGKDTLNHRTRMKYMINQHLSNLKKSQKRWFDPLILISRTERSTNRDPDAYRYKWSNGSNNFQEHLDHFVSERKSRFRVVFDRLRINQYSIDWSEVIDKKGLSKPFRFFLSKSLLFLSKSLLFLSKFLFFLSNSLPFFFVSFGNIPIHRSEIYIYELKGPNDQLCNQLLESIGLQIVHLKKLKPFLLDDHDTSQKSKFLINGGTISPFLFNKIPKWMIYSFHTRNNRRKSFANTDSYFSTIFHDQDYWLNPVKPFHRSSLISSFYKANQLRFLNNPHHFCFYCNKRFPFYVEKARINNSDFTYGQFLNILFIHNKIFSLCVGKKKHAFWGRDTISPIESRVSNIFIPNDFPQGGGDETYNLYKSSHFPSRSDPFVRRAIYSIADISGTPLTEGQIVNFERTYCQPLSDLNLSDSEGKNSHQYLNFNSNMGLIHTPCSEKYLPSEKRKNRSLFLKKYVEKGQMYRTFQRDSAFSTLSKWNLFQTYIPWFLTSTGHKYLNWIFLDTFSGLLPIHLLPIHRLPILSSSQKFVSIFHDIMHVLDISWRILQKKLGLPQRNPIRKISSKCLHNLLLSEEMIHRNNESPLISTHLRSPNVREFLYSILFLLLVAGYLVRTHLIFVSRASSELQIEFEKVKSLMISSYMIELRKLLDRYPTSEPNSFWLKNLFLVALEQLGDSLEEIWGFASGGNMLLGGDSAYGVKSIRSKKKYLNINLIDLISIIPNPISRITFSKNTRHLSHTSKEIYSLIRKRKNVNGDWIDDKIESWVANSDSIDDEEREFLVQLSTLTTEKRIDQILLSLTHSDHLSKNDSGYQMIEQRGAIYLRYLVDIHKKYLMNYEFNTSCLAERRIFLAHYQTITYSQTSCGANSFHLPSHGKPFSLRLALSPSRGILVIGSIGTGRSYLVKYLATNSYVPFITVFLNKFLDNLSEDIDASEDIDASEDIDASEDIDASDDIDRDLHTELELLTMDMMSEKDRFYITLQFELAKAMSPCIIWIPNIHDLDVNESNYFSLGLLVNHLSRDCERCSTRNILVIASTHIPQKVDPALIAPNKLNTCIKIRRLLIPQQRKHFFTLSYTRGFRLEKKMFHTNGFGSITMGSNARDLVALTNEALSISITQKKSIIDTNTIRSAFHRQTWDLRSQVRSVQDHGILFYQIGRAVAQNVLLSNCPIDPISIYIKKKSCNEGDSYLYKWYFELGTSMKKLTILLYLLSCSAGSVAQDLWSLPGPDERNGITSYGLVENDSDLVHGLLQVEGALVGSSRTEKDCSQFDNDRVTLLLRPEPRNPLDMMQNGSCSILDQRFLYEKNESEFEEGEGALDPQQIEEDLFNHIVWAPRIWHPWGILFDCIERPNELGFPYWSRSFRGKRILYDEEDELQENDSEFLQSGTMQYQTRDRSSKEQGFFRISQFIWDPADPLFVLFKDQSSVSVFSHRELFADEEMSKGLLTSQTDPPTSIYKRWFIKKTQEKHFELLINRQRWFRTTSSLSNGSFRSNTLSESYQYLSNLFLSNGTLLDQMTKTLLRKRWLFPDEMKIGFMEQEKDFPFLSRKVMWP
What is the function of this protein?
Probable ATPase of unknown function.  Its presence in a non-photosynthetic plant (Epifagus virginiana) and experiments in tobacco indicate that it has an essential function which is probably not related to photosynthesis.
What are the official names of this protein?
Protein Ycf2.
What is the protein family that this protein belongs to?
Belongs to the Ycf2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: LFTR_PSE14
Sequence: MLTWLNRNSLDFPPLEKALREPNGLLAAGGDLSADRLLNAYRHGCFPWFQDGQPILWWSPDPRTVLFPEELHVSRSLGKMLRQSRYHVTFDRDFASVIKACAAPRSYANETWITGSMQDAYLELHRRGHAHSVEVWDQNELVGGLYGLAMGQLFFGESMFSRADNASKVGFATLVQHLTDWGFVLIDCQMPTQHLHSFGARSIPRQTFADYLSRHLDQPSGADWSYRRV
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TATC_HELPY
Sequence: MFEDLKPHLQELRKRLMVSVGTILVAFLGCFHFWKSIFEFVKNSYKGTLIQLSPIEGVMVAVKISFSAAIVISMPIIFWQLWLFIAPGLYKNEKKVILPFVFFGSGMFLIGAAFSYYVVFPFIIEYLATFGSDVFAANISASSYVSFFTRLILGFGVAFELPVLAYFLAKVGLITDASLKAYFKYAIVVIFIVAAIITPPDVVSQIFMALPLVGLYGLSILIAKMVNPAPKDNENNNENNNENNTKENTKSES
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
What are the official names of this protein?
Sec-independent protein translocase protein TatC.
What is the protein family that this protein belongs to?
Belongs to the TatC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS7_HAEIN
Sequence: MQPTLFIDRDGTLIDEPKTDFQIDSLEKLKLEPKVIPALLRLKAKYRFVIVSNQDGLGTDAFPQTDFDKPHNVMMALFESQGITFDEVLICPHKPEENCLCRKPKIKLLDHYIRKNLFDIDRSFVIGDRETDVQLAENLGIRAIQYDPQKMNWDLIAEKLLGETVTNCGKRPPRFAEVIRQTKETDIKVQVWLDEAGVNEIKTGVGFFDHMLDQIATHGGFRMNVQCKGDLWIDEHHTVEDTALALGQALKQAVGDKRGIARFGFVLPMDECKAECALDLSGRPWIKFNACFKRDKVGDFSTELTEHFFQSLAFSMLATLHLNVTGNNDHHKIESLFKAFGRTLRQAIRIEGNEMPSSKGVL
What are the official names of this protein?
Histidine biosynthesis bifunctional protein HisB.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCA_PSEA6
Sequence: MSLNFLDFEKPIADLEAKIEGLRLVNQGGEFDISIEEEITKLREKSAEMSKKIFADLGAWQVSQLARHPMRPYTLDYIPRIFSEFDELAGDRAFADDKAIIGGLAMLDEQPIMVIGHQKGRDTKEKIKRNFGMPKPEGYRKALRLMEMAERFNLPIITFIDTPGAYPGVGAEERGQSEAIARNLKVMAGLKVPIICTVIGEGGSGGALAIGVGDRVNMLQYSTYSVISPEGCASILWKSADKAPLAAEAMGVAAGQIKELGLINSIVEEPLGGAHRDHDVAAANLKATIKQQLAQLKSLSVEELLDQRYERLMSFGYC
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROK_IDILO
Sequence: MAEKRNIFLVGPMGAGKSTIGRQIARQLHLEFYDSDSEIERRTGAEISWVFELEGEEGFRAREEKVIEELTENMGIVLATGGGSVMSKESRNRLSARGVVVYLKTPIEKQLARTQRDKRRPLIAEAEDPRKVLEELAQERDPLYEEIADITVQTDEQSAKFVVNDIIEQLESINGLG
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_MYCPA
Sequence: MAHKKGASSSRNGRDSAAQRLGVKRFGGQIVKAGEIIVRQRGTKFHPGTGVGRGGDDTLFAKQAGAVEFGIKRGRKTVNIVAAGQAAD
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: FLGL_BACSU
Sequence: MRVTQGMIQQNSLRYIGSSYSKLDKLQSQISSGKKISKASDDPVVAMKSLKYNTQLSQVQQYKSNASQAFTWLENTETNITEGIDILSKVRELAVEAQNDTNGEPERQAIGVEVKQLKEQLLNIANTQVNGRYIFNGTNSDKPPVTDNGDGTYTISDTADVVVNISNNMSLKVNSDPKSAFGGTSESGQNVFEMLDSFEKALNSGSLDGMDSVLNDIDHFSDGMSAERSDLGARYNRLELVNTRLSAQEETATKVLSDNEDVELEEVITEFIAQQSVHRATLAVNAQIVQPTLIDFLK
What are the official names of this protein?
Flagellar hook-associated protein 3, HAP3.
What is the protein family that this protein belongs to?
Belongs to the bacterial flagellin family.
What are the subcellular locations of this protein?
Secreted. Bacterial flagellum.
Protein: RAA4A_ARATH
Sequence: MTSGGGYGDPSQKIDYVFKVVLIGDSAVGKSQILARYARDEFSLDSKATIGVEFQTRTLVIDHKSVKAQIWDTAGQERYRAVTSAYYRGAVGAMLVYDITRRQTFDHIPRWLEELRAHADKNIVIILIGNKSDLVDQRAIPTEDAKEFAEKEGLFFLETSAFNATNVESAFSTVLTEIFNIVNKKSLAASEDQENGNPGSLAGKKIDIVPGPGQVIPNKSNMCCNS
What is the function of this protein?
Intracellular vesicle trafficking and protein transport.
What are the official names of this protein?
Ras-related protein RABA4a, AtRABA4a.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: SYT_STRR6
Sequence: MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKLIDTTRAITEDGSIEIVTPDHEDALPILRHSATHLFAQAARRLFPDIHLGVGPAIEDGFYYDTDHTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIEEHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIYGTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRELERYIVNKELVSGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPMNCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTPEQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAALDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADGEDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVAKKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQTVSVDNFVQAILADIANKSRVEK
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RN111_HUMAN
Sequence: MSQWTPEYNELYTLKVDMKSEIPSDAPKTQESLKGILLHPEPIGAAKSFPAGVEMINSKVGNEFSHLCDDSQKQEKEMNGNQQEQEKSLVVRKKRKSQQAGPSYVQNCVKENQGILGLRQHLGTPSDEDNDSSFSDCLSSPSSSLHFGDSDTVTSDEDKEVSVRHSQTILNAKSRSHSARSHKWPRTETESVSGLLMKRPCLHGSSLRRLPCRKRFVKNNSSQRTQKQKERILMQRKKREVLARRKYALLPSSSSSSENDLSSESSSSSSTEGEEDLFVSASENHQNNPAVPSGSIDEDVVVIEASSTPQVTANEEINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSRISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASDTASAVTSSQPSTVSETSATLTSNSTTGTSIGDDSRRTTSSAVTETGPPAMPRLPSCCPQHSPCGGSSQNHHALGHPHTSCFQQHGHHFQHHHHHHHTPHPAVPVSPSFSDPACPVERPPQVQAPCGANSSSGTSYHEQQALPVDLSNSGIRSHGSGSFHGASAFDPCCPVSSSRAAIFGHQAAAAAPSQPLSSIDGYGSSMVAQPQPQPPPQPSLSSCRHYMPPPYASLTRPLHHQASACPHSHGNPPPQTQPPPQVDYVIPHPVHAFHSQISSHATSHPVAPPPPTHLASTAAPIPQHLPPTHQPISHHIPATAPPAQRLHPHEVMQRMEVQRRRMMQHPTRAHERPPPHPHRMHPNYGHGHHIHVPQTMSSHPRQAPERSAWELGIEAGVTAATYTPGALHPHLAHYHAPPRLHHLQLGALPLMVPDMAGYPHIRYISSGLDGTSFRGPFRGNFEELIHLEERLGNVNRGASQGTIERCTYPHKYKKVTTDWFSQRKLHCKQDGEEGTEEDTEEKCTICLSILEEGEDVRRLPCMHLFHQVCVDQWLITNKKCPICRVDIEAQLPSES
What is the function of this protein?
E3 ubiquitin-protein ligase (PubMed:26656854).  Required for mesoderm patterning during embryonic development (By similarity).  Acts as an enhancer of the transcriptional responses of the SMAD2/SMAD3 effectors, which are activated downstream of BMP (PubMed:14657019, PubMed:16601693).  Acts by mediating ubiquitination and degradation of SMAD inhibitors such as SMAD7, inducing their proteasomal degradation and thereby enhancing the transcriptional activity of TGF-beta and BMP (PubMed:14657019, PubMed:16601693).  In addition to enhance transcription of SMAD2/SMAD3 effectors, also regulates their turnover by mediating their ubiquitination and subsequent degradation, coupling their activation with degradation, thereby ensuring that only effectors 'in use' are degraded (By similarity).  Activates SMAD3/SMAD4-dependent transcription by triggering signal-induced degradation of SNON isoform of SKIL (PubMed:17591695).  Associates with UBE2D2 as an E2 enzyme (PubMed:22411132).  Specifically binds polysumoylated chains via SUMO interaction motifs (SIMs) and mediates ubiquitination of sumoylated substrates (PubMed:23751493).  Catalyzes 'Lys-63'-linked ubiquitination of sumoylated XPC in response to UV irradiation, promoting nucleotide excision repair (PubMed:23751493).  Mediates ubiquitination and degradation of sumoylated PML (By similarity).  The regulation of the BMP-SMAD signaling is however independent of sumoylation and is not dependent of SUMO interaction motifs (SIMs) (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase Arkadia, RING finger protein 111, hRNF111, RING-type E3 ubiquitin transferase Arkadia.
What is the protein family that this protein belongs to?
Belongs to the Arkadia family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Nucleus, PML body. Note=Upon TGF-beta treatment, translocates from nucleus to cytosol.
Protein: IAPP_HUMAN
Sequence: MGILKLQVFLIVLSVALNHLKATPIESHQVEKRKCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTYGKRNAVEVLKREPLNYLPL
What is the function of this protein?
Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
What are the official names of this protein?
Islet amyloid polypeptide, Amylin, Diabetes-associated peptide, DAP, Insulinoma amyloid peptide.
What is the protein family that this protein belongs to?
Belongs to the calcitonin family.
What are the subcellular locations of this protein?
Secreted.