PharMolix/UniProtQA huggingface dataset:
Protein: EBNA1_EBVG
Sequence: MSDEGPGTGPGNGLGQKEDSSGPEGSGGSGPQRRGGDNHGRGRGRGRGRGGGRPGAPGGSGSGPRHRDGVRRPQKRPSCIGCKGAHGGTGSGAGAGGAGAGGAGAGGGAGAGGGAGGAGGAGGAGAGGGAGAGGGAGGAGGAGAGGGAGAGGGAGGAGAGGGAGGAGGAGAGGGAGAGGGAGGAGAGGGAGGAGGAGAGGGAGAGGAGGAGGAGAGGAGAGGGAGGAGGAGAGGAGAGGAGAGGAGAGGAGGAGAGGAGGAGAGGAGGAGAGEEAGGAGAGGGAGGAGAGGAGGAGAGGAGGAGAGGAGGAGAGGGAGAGGAGAGGGGRGRGGSGGRGRGGSGGRGRGGSGGRRGRGRERARGRSRERARGRGRGRGEKRPRSPSSQSSSSGSPPRRPPPGRRPFFHPVGDADYFEYLQEGGPDGEPDVPPGAIEQGPTDDPGEGPSTGPRGQGDGGRRKKGGWFGKHRGQGGSNPKFENIAEGLRVLLARSHVERTTEEGNWVAGVFVYGGSKTSLYNLRRGIALAVPQCRITPLSRLPFGMAPGPGPQPGPLRESIVCYFMVFLQTHIFAEVLKDAIKDLVMTKPAPTCNIKVTVCSFDDGVDLPPWFPPMVEGAAAEGDDGDDGDEGGDGDEGEEGQE
What is the function of this protein?
Responsible for the origin of replication (oriP) dependent replication and maintenance of viral episomes during latent infection.  EBNA1 dimer interacts with the DS (dyad symmetry) element within the origin of replication oriP and with a host mitotic chromosome to initiate viral DNA replication during latency.  EBNA1 binding to DS recruits the host origin recognition complex (ORC).  Governs the faithful mitotic segregation of the viral episomes by binding both the FR (family of repeats) element within oriP and the host mitotic chromosomes.  Forms a cell cycle-dependent tyrosine-dependent DNA cross-link and single-strand cleavage at oriP required for terminating replication and maintaining viral episomes.  Counteracts the stabilization of host p53/TP53 by host USP7, thereby decreasing apoptosis and increasing host cell survival.  Induces degradation of host PML through the ubiquitin-proteasome system, which promotes lytic reactivation and may impair the host cell DNA repair.  Displays inhibitory effects on a SUMO2-modified complex that includes STUB1, KAP1 and USP7.  This inhibitory effect possibly participates to the maintenance of latency linked to PML silencing.
What are the official names of this protein?
Epstein-Barr nuclear antigen 1, EBNA-1, EBV nuclear antigen 1.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae EBNA1 family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: RL11_KOSOT
Sequence: MAKKIIAKIKLQLEAGKATPAPPVGPALGQHGVNIMDFCKKFNAVTADKPGMVFPAVITVYADRSFTFELKTPPASFLILKAAGIKKGSGEPNKVKVGKITKAQVEEIAKIKMPDLNARTLEAAMKIIEGTARNMGVEVVD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: DNAA_BRUAB
Sequence: MKMDSAVSEEAFERLTAKLKARVGGEIYSSWFGRLKLDDISKSIVRLSVPTAFLRSWINNHYSELLTELWQEENPQILKVEVVVRGVSRVVRSAAPAETCDNAEAKPAVTPREKMVFPVGQSFGGQSLGEKRGSAVVAESAAATGAVLGSPLDPRYTFDTFVDGASNRVALAAARTIAEAGSSAVRFNPLFIHASVGLGKTHLLQAIAAAALQRQEKARVVYLTAEYFMWRFATAIRDNNALSFKEQLRDIDLLVIDDMQFLQGKSIQHEFCHLLNTLLDSAKQVVVAADRAPSELESLDVRVRSRLQGGVALEVAAPDYEMRLEMLRRRLASAQCEDASLDIGEEILAHVARTVTGSGRELEGAFNQLLFRQSFEPNISIDRVDELLGHLTRAGEPKRIRIEEIQRIVARHYNVSKQDLLSNRRTRTIVKPRQVAMYLAKMMTPRSLPEIGRRFGGRDHTTVLHAVRKIEDLVGADTKLAQELELLKRLINDQAA
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTXX_METBF
Sequence: MRARANRARVAMGIRDPNSKMLESAWKAQELGYAQVVLVGIKKEIDKVGTELEVVDTDEPEKTLAELMISRKVDAAIRGTAKASGALAQLKEALGKKRICRLALLLTVDGTPFFLAPVGIDEGNTISDKLRMIKLGAEHIRRFGIEPRVGVLSGGRIGDIGRNKRVDRTLADGEFVTRRAVELGINAKHYTILIEDAIKESNFIVAPDGISGNLIFRTIAFLGGGDGLGASVLMDDYVFVDTSRVGGHFTKAIMLASALSHLNKERQKVIY
What are the official names of this protein?
Putative methyltransferase mtx subunit X.
What is the protein family that this protein belongs to?
Belongs to the MtxX family.
Protein: PROA_HYPNA
Sequence: MTVQTSPPSAALAETMLDMGRRARAASRELGLLTAQDRTRGLKAIAAAIRAAAPDVLRANAEDMAAARAKGLAPAMLDRLALDEKRLEGVAAGVETVAALPDPLGRELARWTPPNGLDIARIAVPLGVIGIIYESRPNVTVDAGVLCLRSGNAAILRGGSESAKSSAALANAMRGALKSEELPVDAIQLVATTNREAVGHMLGGLEGALDVIVPRGGRSLVERVQAEARVPVIGHLEGLCHTYVHAAADPKKAVDIVLNAKMRRTGVCGSTETLLIDVAVAATLLPQIAKALTDAGCELRGDGRTRAILGDITPATEADWATEYLDAILSIAVVDGLPGALAHLARWSSGHTDAIITEDTAAAETFIANVDSAIVLHNASTQFADGGEFGFGAEIGIATGRIHARGPVGAEQLTTYKYAVRGTGQVRP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y7203_DICDI
Sequence: MGNAPSRTEPTCDNSINFIIPKENKSYQCYPEQVESNPIDSINSVYFYKTT
What are the official names of this protein?
Uncharacterized protein DDB_G0286943.
Protein: NORW_ECO24
Sequence: MSNGIVIIGSGFAARQLVKNIRKQDATIPLTLIAADSMDEYNKPDLSHVISQGQRADDLTRQTAGEFAEQFNLRLFPHTWVTDIDAEARVVKSQNNQWQYGKLVLATGASAFVPPVPGRELMLTLNSQQEYRACETQLRDARRVLIVGGGLIGSELAMDFCRAGKAVTLIDNAASILASLMPPEVSSRLQHRLTEMGVHLLLKSQLQGLEKTDSGILATLDRQRSIEVDAVIAATGLRPETALARRAGLTINRGVCVDSYLQTSNDDIYALGDCAEINGQVLPFLQPIQLSAMVLAKNLLGNNTPLKLPAMLVKIKTPELPLHLAGETQRQDLRWQINTERQGMVARGVDDADQLRAFVVSEDRMKEAFGLLKTLPM
What is the function of this protein?
One of at least two accessory proteins for anaerobic nitric oxide (NO) reductase.  Reduces the rubredoxin moiety of NO reductase.
What are the official names of this protein?
Nitric oxide reductase FlRd-NAD(+) reductase, Flavorubredoxin reductase, FlRd-reductase, FlavoRb reductase.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BZP1D_WHEAT
Sequence: MGSSEAETPAKANKASAPQEQQPPATSSTATPTVYPDWTSFQGYPPIPPHGFFPSPVVSNPQGHPYMWGPQPMMPPYGSPPYVIYPPGGIYAHPSMRPGAHPFAPYTMTSPNGNPDAAGTTTTAATAGGETNGKSSEGKEKSPIKRSKGSLGSLNMITGKNCVEHGKTSGASANGTISQSGESGSESSSEGSEANSQNDSQHKESGQEQDGDVRSSQNGVSPSPSQAQLKQTLAIMQMPSSGPVPGPTTNLNIGMDYWANTASSSPALHGKVTPTAIPGAVAPTEPWMQDERELKRQKRKQSNRDSARRSRLRKQAECEELAQRAEVLKQENASLKDEVSRIRKEYDELLSKNSSLKDNVGDKQHKTDEAGLDNKLQHSGDDSQKDTN
What is the function of this protein?
Probable transcription factor that may be involved in responses to fungal pathogen infection and abiotic stresses.
What are the official names of this protein?
bZIP transcription factor 1-D, TabZIP1-D.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ADRF_PENRW
Sequence: MSLLQDIVLIITGSASGIGLATATAALSQGAKILGVDVSWAPVSLTEHASYKFIQANLTHEATPKQVVETCIKEFGRIDGLLNIAGIMDQNSSVDSLTDDMWERCIAINLTAPVKLMREVIPIMRQQKSGSIVNVGSKAATSGAASGVAYTASKHGLMGATKNVAWRYKQEGIRCNAVCPGGVPTGIVQASDPTTWDKDALATMSHIHQAHAADRQEGLGVEAEDIANCLLFLVSSQSKRINGAIIPVDNAWSVI
What is the function of this protein?
Short chain dehydrogenase; part of the gene cluster that mediates the biosynthesis of andrastins, meroterpenoid compounds that exhibit inhibitory activity against ras farnesyltransferase, suggesting that they could be promising leads for antitumor agents (Ref. 2).  The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid (DMOA) by the polyketide synthase adrD via condensation of one acetyl-CoA starter unit with 3 malonyl-CoA units and 2 methylations (Ref. 2).  DMAO is then converted to farnesyl-DMAO by the prenyltransferase adrG (Ref. 2).  The methyltransferase adrK catalyzes the methylation of the carboxyl group of farnesyl-DMAO to farnesyl-DMAO methyl ester which is further converted to epoxyfarnesyl-DMAO methyl ester by the FAD-dependent monooxygenase adrH (Ref. 2).  The terpene cyclase adrI then catalyzes the carbon skeletal rearrangement to generate the andrastin E, the first compound in the pathway having the andrastin scaffold, with the tetracyclic ring system (Ref. 2).  The post-cyclization tailoring enzymes adrF, adrE, adrJ, and adrA, are involved in the conversion of andrastin E into andrastin A.  The short chain dehydrogenase adrF is responsible for the oxidation of the C-3 a hydroxyl group of andrastin E to yield the corresponding ketone, andrastin D.  The ketoreductase adrE stereoselectively reduces the carbonyl moiety to reverse the stereochemistry of the C-3 position to yield andrastin F.  The acetyltransferase adrJ is the acetyltransferase that attaches the acetyl group to the C-3 hydroxyl group of andrastin F to yield andrastin C.  Finally, the cytochrome P450 monooxygenase adrA catalyzes two sequential oxidation reactions of the C-23 methyl group, to generate the corresponding alcohol andrastin B, and aldehyde andrastin A (Ref. 2).
What are the official names of this protein?
Short chain dehydrogenase adrF, Andrastin A biosynthesis cluster protein F.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: TRMD_CUPMC
Sequence: MQFDVITLFPEMFRALTDWGITSRAAKQQRYALRTWNPRDFTVDNYRTIDDRPYGGGPGMVMLAKPLEDAIDAAAAAQSDAGVGRPHVVLMSPQGATLTHEKVMALSQRPGLVLLCGRYEAIDQRLIDRRVDEEISLGDFVLSGGELPAMALIDAVVRHLPGVLGDAQSAVQDSFVNGLLDCPHYTRPEEYEGVRVPDVLLGGHHAEIEKWRRRQALANTARKRPDLIVAAREQGLLSKADEKFLSELAAKAGQEFAPAK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANC_CHLL2
Sequence: MQIITEPCQMQAVVEKLRLNRQLIGVVMTMGALHEGHLSLIKQARSLAGTVILTIFVNPKQFGPDEDFHRYPRPFELDASHAKAAGVDYLFAPSPEAIYPEGFQTTVQTGAVAEGLEGMKRPGHFNGVATVVTKLLLITKPHIALFGEKDAQQLAVINRLVRDLNLDVRIIGAPIVREENGLAVSSRNIYLSKEQRESATVLFRGILHAEKELAAGRTDLAGIAGEIERMIAGEPECRPDYVCFVHDNDFMTAETAEPAGEYRLLIAAYAGTVRLIDNRRFTT
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_STAAN
Sequence: MAQISKYKRVVLKLSGEALAGEKGFGINPVIIKSVAEQVAEVAKMDCEIAVIVGGGNIWRGKTGSDLGMDRGTADYMGMLATVMNALALQDSLEQLDCDTRVLTSIEMKQVAEPYIRRRAIRHLEKKRVVIFAAGIGNPYFSTDTTAALRAAEVEADVILMGKNNVDGVYSADPKVNKDAVKYEHLTHIQMLQEGLQVMDSTASSFCMDNNIPLTVFSIMEEGNIKRAVMGEKIGTLITK
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRD_POLAQ
Sequence: MIDRYSLLRPWLFCLDPEQAHNLTLKNLDRAQRFGLLQRLVSKPIADPQNLCGIEFPNPVGLAAGLDKDGKHIDSLAALGFGFLEIGTVTPRPQAGNPKPRMFRLPQAEAIINRMGFNNDGVEACVSRVRQSIFWQRGGVLGLNIGKNAITPIEDAASDYIAAMEAVYEIATYITVNISSPNTQNLRALQGEDMLRSLLRSLDDARKRLSDRYGVRKPLFLKIAPDLDQNDIHLIADLLMEFNIDAVIATNTTISREAVTGMQYGEETGGLSGAPVRIASNIVIRALKARLGVQLPIIGVGGILSGADAREKIMAGASLVQLYSGLIYKGPDLVSECAKALRQS
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HFQ_MARN8
Sequence: MSKGHSLQDPYLNALRKERIPVSIFLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPARNVRLPQQNPAGEGESED
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: SRD45_CAEEL
Sequence: MYRTVLSVFYPMFFILVIPSLILLIFIILRYSPDCFQTFKYILLVTCISQIVAVTTNCLIQIRQVSNLTPMEIWCYGPLRHFTALIAYSTYFLTQTAVVISNVLIFLTIYLKYLATKINTRKTCNYGVTFFILSPIFIALGAQTSLILTEGIPSENQDHLEKINFDISDHAVIGYIRLKTLPSIIITFVITGTILILPAVGLLLRKKTLRNINSNKFSITKKALIKGFINGVTLQVFLPLICYIPVFGSFLVLAETKTEVPFEQYFFSVLVMLPMLFDPYIILYSVAPYRKQIEKWIKTKRRQSILIVDPAARIGF
What are the official names of this protein?
Serpentine receptor class delta-45, Protein srd-45.
What is the protein family that this protein belongs to?
Belongs to the nematode receptor-like protein srd family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NHAA_YERPY
Sequence: MTNIIRQFLRQEAAGGLILIIAAAIALLMANSALQGVYQSFLDIPVSIKIASLDISKPLLLWINDGLMAVFFLMVGLEVKRELMEGSLAGRDKAVFPAIAALGGMLAPALIYLLFNGADEVTRQGWAIPAATDIAFALGVMALLGNRVPTGLKVFLLALAIIDDLGVIIIIALFYTQQVSLQSLGIAAAAIALLAYMNWRGVGKTSAYLLVGLVLWVCILKSGVHATLAGVIVGFMIPLHTQDQRSPSESLEHGLHPWVAYLILPLFAFANAGVSLQGVSLSGLTSLLPMGIATGLFIGKPLGIFTFSWLAVKLGIAKLPDAINFKQIFAVSVLCGIGFTMSIFIASLAFEGTDIALTTYSKLGILLGSTTAAVVGYSLLRLVLPARRKAVNVR
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: QUEC_RUEST
Sequence: MKTLVICSGGLDSVSLAHITSQKYQLTRLVSFDYGQRHRKELDFARAAATRLGVPFHLIDMRSIGGALSGSALTDDIDVPDGHYAEDTMRITVVPNRNAIMLAIGFGVAAAQGDEAVATAVHGGDHFIYPDCRPGFTRAFETMQRAALDGYADVRLHTPFVEQSKADIVRAGAAHNTPFAETWSCYKGGDIHCGRCGTCVERREAFHLAEVADPTVYADPDYWSAAIAGREAE
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: AES1_SCHPO
Sequence: MTEHSFKQIDVFSNKGFRGNPVAVFFDADNLSQKEMQQIAKWTNLSETTFVQKPTIDKADYRLRIFTPECELSFAGHPTIGSCFAVVESGYCTPKNCKIIQECLAGLVELTIDGEKDEDTWISFKLPYYKILQTSETAISEVENALGIPLNYSSQVSPPVLIDDGPKWLVIQLPNATDVLNLVPKFQSLSQVCKNNDWIGVTVFGELGKDSFESRSFAPLIHVNEDPACGSGAGAVGVYIGSSQKTPTSLSFTISQGTKLSRQAISKVSVDVSSNKSIAVFVGGQAKTCISGKSFI
What is the function of this protein?
May have isomerase activity (By similarity).  Enhances target gene silencing when coexpressed with antisense RNA.
What are the official names of this protein?
Antisense-enhancing sequence 1, AES factor 1.
What is the protein family that this protein belongs to?
Belongs to the PhzF family.
Protein: RIBL_METTP
Sequence: MRGTMTRVMATGTFDILHPGHLLYLERSRALGDELVVVVARDINVKHKPRPVVPEDQRLRMVSALKMVDMAVLGSVTDIFEPVRALRPDIITLGYDQYMDENWLEGELRKRGLMARVVRISEREPCELCSSRQIVEKILKERC
What is the function of this protein?
Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
What are the official names of this protein?
FAD synthase, FMN adenylyltransferase, Flavin adenine dinucleotide synthase.
What is the protein family that this protein belongs to?
Belongs to the archaeal FAD synthase family.
Protein: DTDA_CENSY
Sequence: MDLLVAHGGDPAGSNMARYLAEGMEPDGKIWHGRHFDLVIIDSPAISADWIGGEYEYDGYVFLSRHGAESGKLALTCHSTGNFAEAQFGGSDREVAIPYPGFQRRYMRRLSERREKFNGFDITIEATHHGPTGLDKPSIFVEVGTTEKQWNDKGLCGAVAELVRETAEEQDEKTPFVICVGGTHYPEKFTDVLLKGEYALGTVVPKRALVNLDDKMFSHILERNAGAAAVLVDEGGLGPEKRRILNMLEGSGLEVISA
What is the function of this protein?
D-aminoacyl-tRNA deacylase with broad substrate specificity.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, D-tyrosyl-tRNA(Tyr) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DtdA deacylase family.
Protein: SJ144_SCHJA
Sequence: MNTCIQLLILCLVTVINSENLTDISTETTIENEIENATETELSEAIEKETENVTETELPDTVKTEIQFETQNLPHNPKQKYCRTEGQYCSRTYFHRCCGNLVCQLHGFFNGTCVQCLAERKFCIWSSECCSKRCRLFRCRKNPYVQVIPY
What are the official names of this protein?
UPF0506 protein SJCHGC03144.
What is the protein family that this protein belongs to?
Belongs to the UPF0506 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RIPA_CORGL
Sequence: MSSASLLWCHSGVSTVRFGERIFTLVAGDLLFAPEEAQVADDSQGLVLNIRFETLNIMGPARRIHLGHVWNDRLTFEYSRSLFGKETLSPDIARLFTDRVPTPPLPAPRKARAVAQVLVSNPADQTSLEEFAEIQGVSARTLQRQFLKSTGYSFSEWRAAQRVCVAASLLAHDFSISVVANLVGFAATSSLTRAFRRHTGATPSTFTTGQIGMGSAGHPPRIPATTTFAEAHQDQQLWIYSGTATVTTPGYCRFMGQGDMVTIPAGTQTRIDVAAGSIAFPVPVGLDEWGMDLTRVVAVNNQQPKPLTILEQSEWSKLSEELLNTPVPVQM
What is the function of this protein?
Under iron limitation, RipA negatively controls the expression of the acn (aconitase), catA (catechol 1,2 dioxygenase), leuCD (isopropylmalate dehydratase), narKGHJI (nitrite/nitrate transporter and nitrate reductase), sdhCAB (succinate dehydrogenase), pta (phosphotransacetylase) and katA (catalase) genes.  Binds to the consensus sequence in the promoter region.
What are the official names of this protein?
HTH-type transcriptional regulator RipA, AraC-type regulator RipA, Repressor of iron proteins A, RIPA.
Protein: IDD6_ARATH
Sequence: MSSSYNTIALSSTPTFLLSSAAAGPGPNNFNRQEAAMTMVQQQPTSSVAPPPKKRRNQPGNPNPDAEVIALSPKTIMATNRFLCEVCNKGFQREQNLQLHRRGHNLPWKLKQKSNKEVRRKVYLCPEPSCVHHDPARALGDLTGIKKHYYRKHGEKKWKCDKCSKRYAVQSDWKAHSKTCGTKEYRCDCGTIFSRRDSYITHRAFCDALIQESARNPTVSFTAMAAGGGGGARHGFYGGASSALSHNHFGNNPNSGFTPLAAAGYNLNRSSSDKFEDFVPQATNPNPGPTNFLMQCSPNQGLLAQNNQSLMNHHGLISLGDNNNNNHNFFNLAYFQDTKNSDQTGVPSLFTNGADNNGPSALLRGLTSSSSSSVVVNDFGDCDHGNLQGLMNSLAATTDQQGRSPSLFDLHFANNLSMGGSDRLTLDFLGVNGGIVSTVNGRGGRSGGPPLDAEMKFSHPNHPYGKA
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
Protein indeterminate-domain 6, chloroplastic.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PYRE_CLOD6
Sequence: MSKVDVVDILKKSDALLEGHFLLSSGKHSNRYVQCAKVLRFPEYAAEVLSTVVEQIKDLDIDLVVGPAMGGVIVSYELGRQLGKEAVFTERKDNTMELRRGFEVKKGAKIIIAEDVVTTGKSTMETKRVLEALGGEVVGVACIADRTNHDIGMPIYSAIKLDIQVYESDECPLCKEGKLPVVKPGSREFKELGM
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: CPHB_SYNEL
Sequence: MLYRIPVSTVGYWHSPWQIHQFLLPIERFIHRNPMLQLDPISKTTHQHSGHKGLVMAIGGAEDKVRGRQILTTFCQRAGGLDAVIGVIPSASREPDAMGRLYHDIFRDIGVREVDILLVGDRADAEQEEMLARLSRCTGIFMSGGDQLRLSALLDETPLLYQLRHQVWEGKSILGGTSAGAAVLGECMIASGGSNEAPNRSLVDLATGLGILPDVLVDQHFHNRNRLARLISAISAHPDKLGVGIDEDTCAMFEADGTLRVLGRGSVTIVDPRDVSYTNYAHVDVNEPLSIYNLRLHILSDGDCYNLRTHQVQHKCILPPLN
What is the function of this protein?
Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.
What are the official names of this protein?
Cyanophycinase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S51 family.
Protein: GATA6_MOUSE
Sequence: MALTDGGWCLPKRFGAAAADAGDSGPFPAREPSSPLSPISSSSSSCSRGGDRGPCGASNCRTPQLDAEAVAGPPGRSLLLSPYASHPFAAAHGAAAPGVAGPGSALSTWEDLLLFTDLDQAATASKLLWSSRGAKLSPFAAEQPEEMYQTLAALSSQGPAAYDGAPGGFVHSAAAAAAAAAAASSPVYVPTTRVGSMLSGLPYLQGAGSGPSNHAGGAGAHPGWSQASADSPPYGGGGAAGGGAAGPGGAGSATAHASARFPYSPSPPMANGAARDPGGYVAAGGTGAGSVSGGGGSLAAMGGREHQYSSLSAARPLNGTYHHHHHHHPTYSPYMAAPLTPAWPAGPFETPVLHSLQGRAGAPLPVPRGPSTDLLEDLSESRECVNCGSIQTPLWRRDGTGHYLCNACGLYSKMNGLSRPLIKPQKRVPSSRRLGLSCANCHTTTTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMKKEGIQTRKRKPKNINKSKACSGNSSGSVPMTPTSSSSNSDDCTKNTSPSTQATTSGVGASVMSAVGENANPENSDLKYSGQDGLYIGVSLSSPAEVTSSVRQDSWCALALA
What is the function of this protein?
Transcriptional activator that regulates SEMA3C and PLXNA2 (PubMed:19666519).  May regulate genes that protect epithelial cells from bacterial infection (By similarity).  Involved in gene regulation specifically in the gastric epithelium (By similarity).  Involved in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression (PubMed:15329343).  Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions (PubMed:15329343).
What are the official names of this protein?
Transcription factor GATA-6, GATA-binding factor 6.
What are the subcellular locations of this protein?
Nucleus.
Protein: RTCA_KORCO
Sequence: MEFIRIDGSYGEGGGSLLRYAIALSSVTMKPVEIYNIRVKRANPGLRPQHLNAVRALARITEATVEGDEVGSTALRFIPRKRAGGSFEIDIGTAGSISLIIQAILPACISSEEEISLRIRGGTDVPLAPPIDYMAEVFLRNMAPLGVRAELKLLRRGHYPRGGGIVELHASPSKLFPIDKVRGEKFDRVLGRCHAVKLPRSVVERISSSAIDTLRKEGLRVEIEEEWSEDGHLGPGAGIVLWTDSNPRIGADELGEKGKPSEVVGKNAASKLLDEIKAGMAFDSHMGDMIIPYLALARGRSRVGISKLTLHAESNIWLVERFLPVKFIVQGGVGSPTVIEVEGAGLEL
What is the function of this protein?
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA.  The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product.  The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
What are the official names of this protein?
RNA 3'-terminal phosphate cyclase, RNA cyclase, RNA-3'-phosphate cyclase.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXB_ALCBS
Sequence: MTQRKDAPLVALIAGEASGDILGAGLMQALENRYPGARFIGVGGEEMAQAGLTSLFPMEKLSVMGITEVLSHLPELLRLRKSLVRFLLEQRPDVVVGIDSPDFTLPIARRLHDRGLKTVHYVSPSVWAWRQGRIKGIKKSIDLMLTLLPFEARFYEEHDVPVAFVGHPLADRIPLETDVAGARKALALDRDARILAVLPGSRGGEVGQLMPAFLDAMVALNHQDPTLQYVIPAANAARREQIQTLLNTQPNLPVSLIDGQSRTVMAAADVVLMASGTATLEGLLLNKPMVVGYRVGAVTYAIVSRLIKSEFFSLPNLLCRQEMVPELLQSQLTTEAIVAAVRRWFDQPEQAQALKIQFQSVHQQLRGGASEKAAAAVARLLEA
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: Y5201_PSEPK
Sequence: MPNTQSPYNAFAMLLSSNGHPVTPAELHGLLIGRSCAGAGFDADAWLADAAQLLEIEPGDSVRNALVGLQEMVKGELTSDDMAIVLLLPTDDAALSDRATALGQWCQGFVTGFGLNAGGKDLSDEAKEVLQDLVAISQVQEALEESEDGESDYMEVMEYLRVAPLLLFSELAKPAAPAPKPSLH
What are the official names of this protein?
UPF0149 protein PP_5201.
What is the protein family that this protein belongs to?
Belongs to the UPF0149 family.