PharMolix/UniProtQA huggingface dataset:
Protein: HEM1_THERP
Sequence: MTMTLSVVAVTHRTAPVTIRERLSLPVEQQCQWLQRWGNQVPEIVLLVTCHRTEVYWLDGEETAHRGVEWLAELGGLTVEELERWVLQRSGAEAVRHAFCVAAGLDSRVVGEPQILGQVRRARDLARAAGTLGPILDRLFSCSLATGRMVRVRAGWSTGKRSLARVAVREAARLCSDLQSARVLVLGAGETGRDVIAALCRCQPAVVWWTNRSPGRLAQIPSEEPVRIVDWSEWPRLVTEADVVFVATNAPEPIVRLEHVTRHARLPRLLVDLAVPRNVDPAISDVPGIRVVTIDDLPADPVPVAAWDGVAVEPYVERAVQRYLRWLEARSIAAEIRAAHETLQSMLERELEKVLRLALRDPARTGEVKRVAAASMARKTLFPLFRALESEPQRVALALRLLAYDR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: HIS6_ACIB3
Sequence: MLAKRIIPCLDVDNGRVVKGVQFLDIRDAGDPVEVARRYNEQGADEITFLDITATHHGRDTTYRTVERMAETVFVPLTVGGGVRKVEDIRALLNAGADKVSINSAAVFNPEFVQEASQHFGAQCIVVAIDAKKTGDNKWEIFTHGGRKPTGIDAIEWAVKMADYGAGELLITSMDADGTKAGYDIALMRAINDRVTIPTIASGGVGNLQHLADGILQGGADAVLAASIFHFGQYTIPEAKQYLAEQGIEMRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_SALHS
Sequence: MRVLGIETSCDETGIAIYDDKKGLLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQAALKEAGLTASDIDAVAYTAGPGLVGALLVGATVGRSLAFAWNVPAIPVHHMEGHLLAPMLEDNPPEFPFVALLVSGGHTQLISVTGIGQYELLGESIDDAAGEAFDKTAKLLGLDYPGGPMLSKMASQGTAGRFVFPRPMTDRPGLDFSFSGLKTFAANTIRSNGGDEQTRADIARAFEDAVVDTLMIKCKRALESTGFKRLVMAGGVSANRTLRAKLAEMMQKRRGEVFYARPEFCTDNGAMIAYAGMVRFKAGVTADLGVTVRPRWPLAELPAA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_BARHE
Sequence: MAIDLKKHKSRRIILTKQGKRTERHIPVLLQPVLAGLIPLVGAKVIDGTFGAGGYTRALLNAGAQVIALDRDPHAIREGQSLVDEFFPRLRLVQGNFSQLDCVVEEKVDAVILDIGVSSMQLDEAERGFSFQKDGPLDMRMAQTGFTAADVVNRLKSDELARIFKILGEERYARRIARMIEKRRCVQPFLRTGDLAHAIEVLVGRKSGERIHPATRVFQALRIYVNDEIGELARGLFAAERVLKPGGRLGVVSFHSLEDRMVKRFFSARSGESVRSRYLPEIEMAPATFFPLFKGGITANKEELERNPRSRSARLRIGVRTEAECLFADMKLFGLAKIASFEGGKK
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KPRS1_LACLA
Sequence: MSYSNLKLFSLSSNHELAQKVAKEIGIELGKVSVGAHSDGETVVHIDESVRGDHVFILQSTSDPVNDNLMELLIMMDALRRASAASINIVLPYYGYARQDRKARAREPITSKLVANMLQIAGADRLITFDLHAPQIQGFFNIPVDHLMGSPLIAEYFRRQLVSAGDDIVVVSPDHGGVGRARKLANFLKAPLSIIDKRRPRANVAEIMNIIGDVQGKKCILIDDMIDTAGTITLAANALKELGATEVYASCTHAVLSGPAIERINNSAITKLVVLDTIEMPEERQSEKIVQLSIAHLLADAIIRIHERRPLSPLFELHLPSEQI
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase 1, RPPK 1, 5-phospho-D-ribosyl alpha-1-diphosphate synthase 1, Phosphoribosyl diphosphate synthase 1, Phosphoribosyl pyrophosphate synthase 1, P-Rib-PP synthase 1, PRPP synthase 1, PRPPase 1.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTRA_METM7
Sequence: MANKKSPAATWPVANGEYVLGNPESCVGVITLGSHGLDQAAVDAGAALSGPCHTENLGIEKVVANYISNPNIRFMIIAGSEVQGHITGQCIKALYENGIGDDGGIIGAKGAIPFMENIGKEPVERLQRQIIDCIDLIDVEDTAKIAAAIKNCTSQDPDAIDEEPMVVDLEGGEAVANTESTSMKPTSPEMALLEARMKIVSEKMNEAAMIAKFNSGYYNGKIQGIAIGLFLSILVFSLL
What is the function of this protein?
Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin.  This is an energy-conserving, sodium-ion translocating step.
What are the official names of this protein?
Tetrahydromethanopterin S-methyltransferase subunit A, N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit A.
What is the protein family that this protein belongs to?
Belongs to the MtrA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: DAPA_YERPP
Sequence: MFTGSIVALITPMDDNGDVDRASLKSLIDYHVASGTAAIVSVGTTGESATLNHDEHVDVVMQTLELADGRIPVIAGTGANSTSEAISLTQRFNDTGVVGCLTVTPYYNRPMQEGLYQHFKAIAESTDLPQILYNVPSRTGCDMLPPTIARLAKIKNIVAVKEATGNLSRVSQIQVLVDDEDFILLSGDDASGLDFMQLGGKGVISVTANIAAREMVELCALAAQGNFAEGRRLNQRLMPLHQHLFVEANPIPVKWAAKRLGLMANDTMRLPMTPLTDPAKRIVEDALKSAGLL
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAF12_HUMAN
Sequence: MNQFGPSALINLSNFSSIKPEPASTPPQGSMANSTAVVKIPGTPGAGGRLSPENNQVLTKKKLQDLVREVDPNEQLDEDVEEMLLQIADDFIESVVTAACQLARHRKSSTLEVKDVQLHLERQWNMWIPGFGSEEIRPYKKACTTEAHKQRMALIRKTTKK
What is the function of this protein?
The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription (PubMed:33795473).  TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC) (PubMed:33795473).  The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13 (PubMed:33795473).  Component of the TATA-binding protein-free TAF complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex (PubMed:10373431, PubMed:7729427, PubMed:8598932, PubMed:8663456, PubMed:9674425, PubMed:9885574).
What are the official names of this protein?
Transcription initiation factor TFIID subunit 12, Transcription initiation factor TFIID 20/15 kDa subunits, TAFII-20/TAFII-15, TAFII20/TAFII15.
What is the protein family that this protein belongs to?
Belongs to the TAF12 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EFTU_HAHCH
Sequence: MAKEKFERSKPHVNVGTIGHVDHGKTTLTAALTRVCSEVWGGQAVAFDGIDNAPEEKARGITIATSHVEYESPIRHYAHVDCPGHADYVKNMITGAAQMDGAILVCSAADGPMPQTREHILLARQVGVPYIVVFLNKADMVDDEELLELVEMEVRDLLSQYEFPGDDTPIIVGSALLALEGKDDNGMGTSAVKKLVETLDAYIPEPERAIDKPFLMPIEDVFSISGRGTVVTGRVERGIVRVGEEVEIVGIKDTTKTTCTGVEMFRKLLDEGRAGENVGVLLRGTKRDDVERGQVLAKPGTITPHTVFESEVYVLSKDEGGRHTPFFKGYRPQFYFRTTDVTGACELPEGVEMVMPGDNVKMKVSLIAPIAMEEGLRFAIREGGRTVGAGVVAKIFE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTC_ACIAC
Sequence: MKAPSDMKHYLQFKDFSAQEYAYLFERAAVIKGKFKRYEKHHPLTDRTLAMIFEKASTRTRVSFEAGMYQLGGSVVHLTTGDSQLGRAEPIEDSAKVISRMVDLVMIRTYEQTKIERFAAHSRVPVINGLTNEFHPCQILADIFTFIEHRGSIQGRTVAWVGDGNNMANTWLQAAELLGFTVHVSTPSGYEVDSRVAGVAAGSHYKVFSDPLEACRGADLITTDVWTSMGYEAENEARKKAFADWCVDAEMMAAARPEALFMHCLPAHRGEEVEADVIDGPQSVVWDEAENRMHVQKALMEYLLLGQVA
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM175_CHICK
Sequence: MAAPRAATPGPGGGARKPELDLELGSSTQTSHRLLAYSDALLSIIATVMILPVAHTKIHPDQKLGESVQQLLLTKIAVYLMTFLIVTVAWAAHVRLFQVIELIDDVLALLNLACMMIITFLPYTFSLMASFPGVPFGIFLFSVCAVVIGLIQAVIVVYGFYHPHLLNQQIQVSENQNFYKRHILKIILRGPALCFLAAIFSFFFIPLSYLLLGLVIVFPHLSRFITWCKTKIVGHRDEEEASYSLETFSFYLSEPLSKERVEAFSDGVYAIVATLLILDICEDNVPDPREVGEKFHGSLLEALSEYGPNYLAYFGSFVTIGLLWFVHHSLFLYVTKATRLMGLLNILSLAFIGGLPLAYQLTSEFAEKSHNEIEAIQVSCVITFFASIFQFAIWTTALLHERETLHPFARYGGKEHAFMFAKLALYPCVSLGAFFLTCLLSEFSTEIFHLMQIVIPFAFLALRIFVRISLTVIKSVMSLSRRKVVLLEEEEACLSPTETHS
What is the function of this protein?
Proton-activated proton channel that catalyzes proton efflux from endosomes and lysosomes to maintain a steady-state pH.  Activated at low pH (under pH 4. 6) by luminal side protons: selectively mediates lysosomal proton release from lysosomes, eliciting a proton leak that balances V-ATPase activity to maintain pH homeostasis.  Regulation of lumenal pH stability is required for autophagosome-lysosome fusion.  May also act as a potassium channel at higher pH, regulating potassium conductance in endosomes and lysosomes.  The potassium channel activity is however unclear as it was tested in non-physiological conditions for a lysosomal channel.
What are the official names of this protein?
Endosomal/lysosomal proton channel TMEM175, Transmembrane protein 175.
What is the protein family that this protein belongs to?
Belongs to the TMEM175 family.
What are the subcellular locations of this protein?
Endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein.
Protein: RLMM_HAEDU
Sequence: MNKLALYCRAGFEKELAGEITDKAAQLGVFGFVNLTEQSGYVIFECYQANEADHLAREIKFEQLIFARQMIVVGELLEDLPTADRISPIIAQYKTLQPKHSSALFVETPDTNEAKALLTFCRKFTVPLRNSLKQEGWLTSSDNVKDSISLHILFIRPGCCYVGYAYNHNKSPFFMGIPRLKFPSDAPSRSTLKLEEAILTFIPINQEKKRFNEQMKGVDLGACPGGWTYQLVKRGLFVYAVDHGKIAATLHETGRIEHCVEDGFKFQPPKLKQMDWLVCDMVERPMRISQLIGKWLMNGWCRETIFNLKLPMKKRYHEVQLCLSLFRQLTKQGLCFKLQAKHLYHDREEITVHIVIMGKK
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBB3_MACFA
Sequence: MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYVPRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRGLKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEGEMYEDDEEESEAQGPK
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.  TUBB3 plays a critical role in proper axon guidance and maintenance.  Binding of NTN1/Netrin-1 to its receptor UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubules and thereby lead to increased microtubule dynamics and axon repulsion.  Plays a role in dorsal root ganglion axon projection towards the spinal cord.
What are the official names of this protein?
Tubulin beta-3 chain, Tubulin beta-4 chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, growth cone. Cell projection, lamellipodium. Cell projection, filopodium.
Protein: RIMM_AERS4
Sequence: MEKPVVLGTLGTVYGIKGWLKVNSFTDVAEAIFDYNPWMINQNGVWRELKVSAWKRHNKGLICKIDGIDLREDALALTNVEIGVPADLLPALPEGEFYWRDLIGCSVSTTKGYDLGKVTELMETGSNDVLVVEANVKDAFGAKERLIPFLEEQVIKHIDLTARTIEVDWDPGF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BTN1_CRYNJ
Sequence: MDKDNQALDELPMLTGSKHANKRLFAAFMIFGLLNNVLYVIILSAALDLVSADTPKGVVALFNIFPALITKVVWPLLSNGKIRYTRRVGFCTICSWFGIITIALSSSLSPRLLGISLASLSSGMGELTFLQLTTTLPTEATSKTALGAWSSGTGFAGVAGAGIWWLLRGLGVKGGLGLSSFLPLFFPITYKYILPPFSHLEASSDSSPYQRLPMSSSLSNNNNFRPPAILISVPSSEYVPQHTPLLSSGFIDRDRDRNRDGEELTDGDKRLMGMRASRLTTQEKMKLLRPLVVRYMLPLCAVYVEEYVINSGVAPTLVFPLPTYGLWSWLFKSPRDYYPFWSLTYQTFVFLSRSSLSLGLPPIPKRLLPLPAIIQFLVLSLLFLQAKTFFFSSPAYTPPADGDGGVDRSITIVFLLICLEGLCGGSGYVNTFYHVGREGSVSENYDADGDNEMGGDRRTVNVTEMEKKAMEREFRIGAVGAADSTGILFASLISMPLEIALCRSQVDQGRTMCREL
What is the function of this protein?
Involved in vacuolar transport and vacuole pH homeostasis.  Also required for cytokinesis (By similarity).
What are the official names of this protein?
Protein BTN1.
What is the protein family that this protein belongs to?
Belongs to the battenin family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: PYRF_COCPS
Sequence: MASKSQFPYEDRARDHPNPLARRLFQIATEKQSNVVVSADVTTTKELLDLADRLGPYMVVLKTHIDILADFSAETITGLQSLSQKHNFLIFEDRKFVDIGNTVQKQYHGGALHISEWAHIVNATVLPGPGIIDALAQVASAPDFPHASDRGLLILATMTSKGSLATGQYTELSVELARKYKGFVLGFVASRSLEGVETAGKADDEDFVLFTTGVNLASKGDALGQQYQTPESAIGGGADFIISGRGIYAAPDPVDAARRYQKAGWDAYLKRVGR
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase, Uridine 5'-monophosphate synthase, UMP synthase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family.
Protein: ENGB_STRA1
Sequence: MAEEFLNTHNASILLSAANKSHYPQDDLPEVALAGRSNVGKSSFINTLLGRKNLARTSSKPGKTQLLNFYNIDDKLRFVDVPGYGYAKVSKTERAKWGKMIEEYLVTRDNLRVVVSLVDFRHDPSADDIQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESSIKKKLNFDKKDHFIVFSSVDRTGLDESWDTILSEL
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: HRCA_CLOD6
Sequence: MELNERKLNILKAIVKDYIETAEAIGSRTISKRHDLGVSAATIRNEMADLEELGYLIQPHTSAGRVPSEKGYKLYVNSLMSKSELDDNDKILIEQCMNHNINHIKELIHETSKLLSQLTNYTTVAVTKSLINQSVIKHIQLVAMNDNNILLIVVTDKGDLKKANLTTNVYLDQSKLNLISDNLTRKLLGKSITDLDDNLIAFIKYEISEYSGLIDELLNALNSNMKEEDFSLSLNGATNIFSYPEFNDVLKAKSFLNMLEKKETIADIIKSKGIQKDNLNIIIGSDNDCELAQDCSIVTATYNVDRDLVGRISFIGPTRMDYARIYSIINYMSLLINRK
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: YQGF_VIBVU
Sequence: MSRTIMAFDFGTKSIGSAIGQEITGTASPLKAFKANDGIPNWDEIEKQIKEWQPNLLVVGLPTDLHGKALETITPRAKKFAQRLQGRFGLPVELHDERLSTTEARSELFSMGGYKALSKGNVDCQSAVIILESWFEAQWG
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_BACCN
Sequence: MTKGILGRKIGMTQVFAENGELIPVTVIEATPNVVLQKKTTETDGYNAIQLGFEDKREKLANKPEQGHVAKASTAPKRFIREIRDADVDGLEVGQEVKVEVFAAGETVDVTGISKGKGFQGAIKRHGQSRGPMSHGSRYHRRPGSMGPVAPNRVFKGKKLAGRMGGDQITIQNLEIVQVDVERNLLLIKGNVPGAKKSLVVVQGAVKASK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: YJJB_ECO5E
Sequence: MGVIEFLLALAQDMILAAIPAVGFAMVFNVPVRALRWCALLGSIGHGSRMILMTSGLNIEWSTFMASMLGGTIGIQWSRWYLAHPKVFTVAAVIPMFPGISAYTAMISAVKISQLGYSEPLMITLLTNFLTASSIVGALSIGLSIPGLWLYRKRPRV
What is the function of this protein?
Involved in succinate export with YjjP.  Both proteins are required for export.
What are the official names of this protein?
Probable succinate transporter subunit YjjB.
What is the protein family that this protein belongs to?
Belongs to the ThrE exporter (TC 2.A.79) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: QUEF_BACTN
Sequence: MAELKDQLSLLGRKTEYKQDYAPEVLEAFDNKHPENDYWVRFNCPEFTSLCPITGQPDFAEIRISYIPDIKMVESKSLKLYLFSFRNHGAFHEDCVNIIMKDLIKLMNPKYIEVTGIFTPRGGISIYPYANYGRPGTKFEQMAEHRLMNRE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_GLAP5
Sequence: MAQVSMRDMLNAGVHFGHQTRYWNPQMKPYIFGARNGVHIINLEKTLPLFNDALAELTRIASNNGKILFVGTKRAASDAVKAAAVESQQFYVNHRWLGGMLTNWKTVRQSIKRLKDLEAQSQDGTFDKLTKKEALDRTRDMAKLELSLGGIKDMAGLPDAIFVIGADYEHIAIKEANNLGIPVFAIVDTNASPAGVNHVIPGNDDAARAIQLYLDAAVAAIKEGRGQETVAAEFVAEEAAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RL11_STRP2
Sequence: MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNARTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTRAQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: EFG_CLOB6
Sequence: MANKEYPLAKFRNIGIMAHIDAGKTTATERILFYTGKTHKIGETHEGGATMDWMEQEQERGITITSAATTCFWKDHQVNIIDTPGHVDFTVEVERSLRVLDGAVTILDAKSGVEPQTETVWRQADNYKVPRMVFINKMDKLGADFLMSVGTLRERLHANAVPLQLPIGAEDAFSGIIDLVKNDAVIYKDDLGTVMDETEIPEDMKEMAEEYRTMLLEAVAEVDEDIMMKYLEGEEISVEEIKTALRKGVLANKIVPVLCGSAYKNKGVQLLLDAIIEFMPSPLDIEDVKGTEPTTGEEMTRPADAKAPLAALAFKIATDPFIGKLAFTRIYSGTMKNGTYVFNSNKGKRERIGRLMKMHANHREEVEELKAGDLGAIIGLKDTTTGDTLCDDADPIILENMEFPEPVIDVSIEPKTKAGQEKMGIALAKLAEEDPTFRTYTNQETGQTIIAGMGELHLEIIVDRLIREFKVECNVGQPQVAYKETVRKHVKAEGKFVRQSGGRGQYGHCWIEMMPTEGEYEFENAIVGGSIPKEYIPAIDNGIQEASQSGIIAGYPVINFKVKLFDGSYHDVDSSEMAFKIAGSMAFKNAMSKADAVLLEPSMKVEVVVPEEYMGDVIGDINSRRGRIEGMTPRAGAEVIRAFVPLSEMFGYATTLRSKTQGRGNYVMQFDHYEEVPKSIQDKVIGERK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_BAUCH
Sequence: MARVKRGVVARARHKKVLKLANGYYGARSRVYRVAFQAVLKAGQYCYRDRRCKKRQFRKLWITRINAAVRQHGITYSCFMNSLKKASIHIDRKILAEIAISDKVAFATLAEKAKSILCVT
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: MNMC_MARMS
Sequence: MLTSYQLESPALSWGEDGAPHSNQFDDVYFDKESGLEETRHVFLKNNQLSGRWASLQKNAFVIAETGFGTGLNFLCAWQAFLTEAASDKQLHFISVEKYPMTKSMLTDALKMWPSISHLSQQLIDAYPEVCHGLHRIELEQGRIQLTLWFGEAEDGFAALDADVDAWFLDGFAPSKNPEMWSDNLFKHIHRLSHQGTTFSTFTAAGIVRRGLKNVGFDVRKVKGFGQKREMTVGELNSSTAPLSARMSQGQAWFNLRQDKTSEITKVLVVGAGLAGANTAYALAKQGIKVEVWEQGNCIAGGASGNPQGMLYPKLASQDTPVNRFYLSAYLHATRLYSSLDRHKQFWDACGLIQIPKNDKEAVRFQKLLDEKLYPEAILQASKDREGCLFLPLSGWVVLTQLCETLLSHENIHVCLNTKLESLSPIELDDKTFGWQARSKYQQAPLNDRQACFSHVVLCTANDTKALGVTPKTPDYPIRGQVSFMDIEKAKAACQTIGESADKIDFDKILCEFGYVSPSINGLLHFGSTYDLKDLDDRVREEGHKRNLAILESLLLLPKETFNSEDCGGRVSFRCAVPDYTPIVGPVQSEDVYQQAYSTLTKNAKWQSNEIAEPIKQLYINIGHGSRGLISTPLSGSYIASLITGTPSPLEQKVSHKLHPSRFIIRDLKRSQIL
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.