PharMolix/UniProtQA huggingface dataset:
Protein: TRD7B_DANRE
Sequence: MADEELVKKMVRAVLQSSKSGLSLSDLQVEYKDLTGELIPYKQLGYVTLDALLHSMPSIVKLDKGQSGEVMCHATTGNEMAHITKLAARQRTAKKTGRPQVVNCQMRVKPAAPLVLNAKPRTSLRQPDHRGRLGRGGGRGHGDTRTGCMRDPQLDGKGGRPHNTPPNTPSRKPSLPSERPEKRMTLPSRFQKEVHAHILRNPQHINVPSNLNENTTPPKPRLPHSAPYSPKLVQSRLQEVLNKHSNGLWVSKLPQLYREHYKQDLPSEALKELENWTHICTVEKPCSSKPQELLLYPAKETSQITPTPTHDRSPSHHKKPQTQRPSLTAKSNTPESPKALSPDLKQKLGELLLKYSSGLWAHALPKLYQDTYKCKLPEFVLDQLTLLSDICTIDYPVPDNPKRAILYAKVVEDENRNQSGLAGQEMKLERRLSSQTVPPLVIPRVEYPSVLVVDASDTNCVILRYIGEGYSKAQEKLEDEMREFYRQDNTKMALRSPSPGQLTAVGAEEEDDIIRAQVCEVMADKVKVYYVDHGFSEVISIRKLFELNEKFYRLPFQATKCKLAGLESFSQEQAVLKKLESIATGKILLAEILEREDMPLVVLYDTSQDDDVNINAACMKALQDRSLESPLKVNSAYMNVSVTSVCSDGTIYCQVPSRGLTKLNEILEKTENYFHSQVTSESLVSRPFCGKNCLARYKGKWSRVEITNLHGSRVLDILFVDVGVQASVEVIELREIPPPLLRDLISTPAQALKCCLAGLPVSVGLWTPDAVQWLRDTVLHISDCSLKIAKVDETKRLAHVYLFTSKNFHDTSCSLNQQLADSDLWNHQKDVFLSSRGPLKSLNVPTATQTSSLKTDRGDKALHTPKKTSPPLGSKSTPAGSPPERLSLPPALELPEIGQNMDVFVSVACHPGHFVLQPWQDMYKLVVLMGEMILHYNKMEEKALKVEKNQVCAAKVENNWYRVLVKGVLTNGLVSVFQLDYGKHELVSGTKLRPLTQEFCQLPFQAITAQLAGLKPRQWSEEASIVFRNHVEKKPLVAQLESVQEASQPWERKVMIYLVDTSQEERDIWLHDIMAEFTDEMTKTA
What is the function of this protein?
Component of specific cytoplasmic RNA granules involved in post-transcriptional regulation of specific genes: probably acts by binding to specific mRNAs and regulating their translation.  Probably required during spermatogenesis (By similarity).
What are the official names of this protein?
Tudor domain-containing protein 7B.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to cytoplasmic RNA granules.
Protein: MYBA_XENLA
Sequence: MAGRARSEDEEEDGQFTEHDYDVSLQKGPKKPWSKLRWTKDEDDKVKKLVEKHGEDWGVVARHFINRSEVQCQHRWHKVLSPELVKGPWTKEEDQRVIELVHKYGPKKWSIIAKHLKGRIGKQCRERWHNHLNPDVKKSSWTEEEDRIIYSAHKRMGNRWAEIAKLLPGRTDNSIKNHWNSTMKRKVEQEGYLQDLMNCDRPSKLQAKSCAAPNHLQAQNQFYIPVQTQIPRYSSLSHDDNCIEIQNSFSFIQQPFVDADDPEKEKRIKELELLLMSAENEVRRKRVPSGSSLTWSESYHMGESMSNTMSHLEEQTHDFYSLDEIPNTSGQQSVEDKILAPEANIVLQPLETIPEFSETLELIDVDTVDWNNIESFELPFTASPAKHTPMKWIHEISPECALNSCLVQADGRGSASRVLSSSPAMPKFYSPPTILRKKKIHPDLSLTPEVRDASNVVLKGTPVKTRQYSPLQLFRSGNVQNHLNLDNLPLTSTPVCGQKISATPLQRQITPKKDKENAGFRTPTIRRSLMAVTPRTPTPFKNALAAQEKKYGPLRTVMQPLIFVEEDIMEVLKKETEKDVFIKEEKESDCKPMKQEHVSTVRKVRKSLILDSCDKEELGADFLAPDEVSQSQNGNTLPTSFLMIPLGERQDQKCDENTDTRKGSVMQRKNYIPATRNVKLQSSVQPLCEWEAVVYGKTEDQLIMTEQARRYLDTYKPTSSSGLRHLIL
What is the function of this protein?
Transcription factor that specifically recognizes the sequence 5'-YAAC[GT]G-3'.  Acts as a master regulator of male meiosis by promoting expression of piRNAs.  The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons, which is essential for the germline integrity.
What are the official names of this protein?
Myb-related protein A, A-Myb, xAMYB, Myb-like protein 1, Myb-related protein 2, XMYB2.
What are the subcellular locations of this protein?
Nucleus.
Protein: SECB_BURCH
Sequence: MSDVENQPFFNIQRVYLKDMSLEQPNSPAIFLEQDMPSVEVEVDVKADRLAESVFEVVVSGTVTAKVKDKVAFLIEAKQAGIFDIRNIPDEQLDPLVGIACPTILFPYLRSNIADAITRAGFPPIHLAEINFQALYEQRLAQLQQQAGAAAGAPNGAPNGTTLN
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXB_FRAT1
Sequence: MRIGIVAGELSGDQLGGTLVEALKQKYPNAIIEGIGGPKMAAAGFKSLYPMDALSLIGFLEIISKGLRILSIRRKIINYFKQNKPDIFIGIDAPDFNLTVEKELRSAGIKTIHYVSPKIWVWREYRIKKIRKATDKILAILPFETEYYKNRHKFEAIYVGHPLAKNIPIHIDRAKYRDKLGLKGSSLPILSVLPGSRTTEVSRLLPLFLLALQKLVDAGYKFKAIMPLAKPSLKPLFAKYKEQIDSLGIEVFETNSHDVLKASDLSLLASGTATLEAMLCKLPMVVGYKLSWLSALIGRMLIGNHSYWAFPNILHKNEIIKELIQEDCTVDNLFSELKRLFDDKRRNDYIVEEFEKIHKEMVIDTESKIIQVLDTMIEKS
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: PSB28_THAPS
Sequence: MIARIQFIKGIDEKVLPDVRLTRSRDGSTGTATFLFKNANLINKSLALNGEITGMYMIDEEGILETRDVSARFVNGKPQAVESIYIMKSPEAWDRFMRFMERYGESNGLAFTKA
What are the official names of this protein?
Photosystem II reaction center Psb28 protein, Photosystem II 13 kDa protein, Photosystem II reaction center W protein.
What is the protein family that this protein belongs to?
Belongs to the Psb28 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: RR8_LEPVR
Sequence: MGKDTIADIITSIRNADMNRKGTVRIRSTNITESIVKILLREGFIENVRKHRENNQYFLILTLRHKRNKKESYKTILNLKRISRPGLRIYSNSQRIPRILGGIGIVILSTSQGIMTDREARRKSIGGEILCYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SDS23_SCHPO
Sequence: MPLSTQSSDSLSSAGRQSFGVNSVSDFLAQFPIPTNLPSNKWQDIPVTFLHDNEIALIDPETSMEEASSILIDRDLSALPIVAAKGSNEIATTFDYADLNSFLLMVVGFDDFNDGRFKKVAEDIRAGKVITAYEVAKLGKNKDDFITIPHTTSLGRLAEILSSGIRRVAVTNEQGELSFMASQRSIIRFLWNNIRAFPDLEPLMSRTIHSLDIGSTDITCISGDQKVAAALRQMNQTGIGSLAVVDAQFRLLGNISLVDVKYVTRSSSVYLLNKSCAHFLSVIKSEQGIRAGKDSAPAFNIYESSTFAFTLAKLVATQCHRLWLVQSPSCPPSPKNNAHLSPGSMGGVKVNQLLGVVSLTDIISVLYAHMKGTLPPAPHSAPSLRHGRRGSTSSHRSHSKASVDTQRR
What is the function of this protein?
Required for normal DNA replication and for proper mitosis.  Induces sexual development and ascus formation.
What are the official names of this protein?
Protein sds23/moc1, Multicopy suppressor of overexpressed cyr1 protein 1, Phosphoprotein at stationary phase 1 protein.
What is the protein family that this protein belongs to?
Belongs to the SDS23 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PA_I78A9
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEICFMYSDFHFIDERGESIIVESGDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGVEKPKLLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSERGEETIEERFEITGTMRRLADQSLPPNFSSLENFRAYVDGFEPNGCIEGKLSQMSKEVNARIEPFLKTTPRPLRLPDGPLCSQRSKVMMMDALKLSIEDPSHEGEGIPLYDAIKCMKTFFGWKEPNIVKPHEKGINPNYLLAWKQVLAELQDIENEEKIPRTKNMKKTSQLKWALGENMAPEKVDFEDCKDVSDLKQYDSDEPESRSLASWIQSEFNKACELTDSSWIELDEIGEDIAPIEHIASIRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKWEKYCVLEIGDMLLRTAIGQVSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAESSVKEKDMTKEFFENKSETWPIGESPKGVEEGSIGKVCRTLLAKSVFNSLYASPQLEGFSAESRKLLLIVQALRDNLEPGTFDLGGLYEAIEECLINDPWVLLNASWFNSFLTHALK
What is the function of this protein?
Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits.  The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching.  It consists in the hijacking and cleavage of host capped pre-mRNAs.  These short capped RNAs are then used as primers for viral mRNAs.  The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
What are the official names of this protein?
Polymerase acidic protein, RNA-directed RNA polymerase subunit P2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=PB1 and PA are transported in the host nucleus as a complex.
Protein: RECA_RHIE6
Sequence: MSQNSLRLVEDKSVDKSKALEAALSQIERSFGKGSIMKLGSNENVIEIETISTGSLGLDIALGVGGLPKGRIIEIYGPESSGKTTLALQTIAESQKKGGICAFVDAEHALDPVYARKLGVDLQNLLISQPDTGEQALEITDTLVRSGAVDVLVVDSVAALTPRAEIEGEMGDSLPGLQARLMSQALRKLTASISKSNTMVIFINQIRMKIGVMFGSPETTTGGNALKFYASVRLDIRRIGSVKEREEVIGNQTRVKVVKNKMAPPFKQVEFDIMYGEGVSKTGELVDLGVKAGIVEKSGAWFSYNSQRLGQGRENAKTFLRDNPDLAREIELALRQNAGLIADRFLQNGGPDADDGDAAADM
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS1_YERPG
Sequence: MLDKTRLRIAMQKSGRLSDESQELLSRCGIKINLQQQRLIAFAENMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGDDPRYFTLRRLDFGGCRLSLAAPLDAEYTGPQCLQDTRIATSYPHILKQYLDKQGVRFKSCLLNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMSVDKQQLIDRLMTRIQGVIQARESKYIMMHAPSERLDEIITLLPGAERPTILPLAGDKSRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA2H1_AGKCL
Sequence: MRTLWIVALLLVGVEGSLLELGKMILQETGKNAITSYGSYGCNCGWGHRGQPKDATDRCCFVHKCCYKKLTDCNHKTDRYSYSWKNKAIICEEKNPCLKEMCECDKAVAICLRENLDTYNKKYKAYFKFKCKKPETC
What is the function of this protein?
Snake venom phospholipase A2 homolog that lacks enzymatic activity.  Has myotoxic activities (PubMed:9920492).  A model of myotoxic mechanism has been proposed: an apo Lys49-PLA2 is activated by the entrance of a hydrophobic molecule (e. g.  fatty acid) at the hydrophobic channel of the protein leading to a reorientation of a monomer (By similarity).  This reorientation causes a transition between 'inactive' to 'active' states, causing alignment of C-terminal and membrane-docking sites (MDoS) side-by-side and putting the membrane-disruption sites (MDiS) in the same plane, exposed to solvent and in a symmetric position for both monomers (By similarity).  The MDoS region stabilizes the toxin on membrane by the interaction of charged residues with phospholipid head groups (By similarity).  Subsequently, the MDiS region destabilizes the membrane with penetration of hydrophobic residues (By similarity).  This insertion causes a disorganization of the membrane, allowing an uncontrolled influx of ions (i. e.  calcium and sodium), and eventually triggering irreversible intracellular alterations and cell death (By similarity).
What are the official names of this protein?
Basic phospholipase A2 homolog MT1, svPLA2 homolog, ACL myotoxin.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. K49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YFDM_ECOLI
Sequence: MSNKYCQALVELRNKPAHELKEVGDQWRTPDNIFWGINTLFGPFVLDLFTDGDNAKCAAYYTAEDNALAHDWSERLAELKGAAFGNPPYPW
What are the official names of this protein?
Putative methyltransferase YfdM.
Protein: ADA1D_RAT
Sequence: MTFRDILSVTFEGPRSSSSTGGSGAGGGAGTVGPEGGAVGGVPGATGGGAVVGTGSGEDNQSSTGEPGAAASGEVNGSAAVGGLVVSAQGVGVGVFLAAFILTAVAGNLLVILSVACNRHLQTVTNYFIVNLAVADLLLSAAVLPFSATMEVLGFWAFGRTFCDVWAAVDVLCCTASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAILALLWAVALVVSVGPLLGWKEPVPPDERFCGITEEVGYAIFSSVCSFYLPMAVIVVMYCRVYVVARSTTRSLEAGIKREPGKASEVVLRIHCRGAATSAKGYPGTQSSKGHTLRSSLSVRLLKFSREKKAAKTLAIVVGVFVLCWFPFFFVLPLGSLFPQLKPSEGVFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQCRRRRRRLWAVYGHHWRASTGDARSDCAPSPRIAPPGAPLALTAHPGAGSADTPETQDSVSSSRKPASALREWRLLGPLQRPTTQLRAKVSSLSHKIRSGARRAETACALRSEVEAVSLNVPQDGAEAVICQAYEPGDYSNLRETDI
What is the function of this protein?
This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium.
What are the official names of this protein?
Alpha-1D adrenergic receptor, Alpha-1A adrenergic receptor, Alpha-1D adrenoreceptor, Alpha-1D adrenoceptor, RA42.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA1D sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GSA_CHLSY
Sequence: MSVVTERYSRSQADYAAAREVIPGGVNSPVRAFRGVGGIPIFFERGQGAYVWDVDGNRYIDYVLSWGPLLLGHAHPAVVEAITLQAQRGTSFGAPTELETELARLVIELVPSIEQIRFVNSGTEATMSALRLARAATGRRLIVKFNGCYHGHADMLLVQAGSGVATLGLPDSPGVPPSVAAETITIEYNDLDAAAALFANRGAEIAAVIVEPIAANMGFVLPKPGFLSGLRELTQTHGAIFILDEVMTGFRVAAGGAQALWGLDPDLTCLGKVIGGGLPVGAYAGKRQLMQLVAPAGPMYQAGTLSGNPLAMTAGLTTLRTAFGGDAGAFQQAVTRTARLADGLRMLGERYRIPVQVGNVGTMFGCYFLRQEGSQITSYAEAKAYADSQRYARFFWAMADQGIYLAPSQFEAGFLSTAHSDADIDETLAAAEVAFAGLVSSAE
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR3_SCHPO
Sequence: MVASLVVLISGSGSNLQAIIDATLNGVLKGEAAVTHVLSNRKNAYGLERAAKAGIPTSLHTLLPYKKEYGPEIGRKKYDAELAEKIIKLQPSLVVCAGWMHILSPEVLIPLETNKIGIINLHPALPGAFNGIHAIERAFEAAQQGKITHTGAMVHWVIAAVDEGKPIIVQEVPILSTDSIEALEEKIHAAEHVILVQAIHQIITDNK
What are the official names of this protein?
Phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase, GAR transformylase, GART.
What is the protein family that this protein belongs to?
Belongs to the GART family.
Protein: REGA_RHOSU
Sequence: MAEQEYEIGEDPSLLIVDDDEPFLRRLARAMEKRGFQPEMAETVAAGKAIASARPPAYAVVDLRLEDGTGLDVVETLREKRPDAKIVVLTGYGAIATAVAAVKVGATDYLSKPADANDVTAALLSNGEALPPPPENPMSADRVRWEHIQRVYEQCDRNVSETARRLNMHRRTLQRILAKRSPR
What is the function of this protein?
Member of the two-component regulatory system RegB/RegA.  Involved in transactivating anaerobic expression of the photosynthetic apparatus.  It is a transcriptional regulator that is responsible for activating expression of the puf, puh, and puc operons in response to a decrease in oxygen tension (By similarity).
What are the official names of this protein?
Photosynthetic apparatus regulatory protein RegA.
Protein: ITB5_MOUSE
Sequence: MPRVPATLYACLLGLCALVPRLAGLNICTSGSATSCEECLLIHPKCAWCSKEYFGNPRSITSRCDLKANLIRNGCEGEIESPASSTHVLRNLPLSSKGSSATGSDVIQMTPQEIAVSLRPGEQTTFQLQVRQVEDYPVDLYYLMDLSLSMKDDLENIRSLGTKLAEEMRKLTSNFRLGFGSFVDKDISPFSYTAPRYQTNPCIGYKLFPNCVPSFGFRHLLPLTDRVDSFNEEVRKQRVSRNRDAPEGGFDAVLQAAVCKEKIGWRKDALHLLVFTTDDVPHIALDGKLGGLVQPHDGQCHLNEANEYTASNQMDYPSLALLGEKLAENNINLIFAVTKNHYMLYKNFTALIPGTTVEILHGDSKNIIQLIINAYSSIRAKVELSVWDQPEDLNLFFTATCQDGISYPGQRKCEGLKIGDTASFEVSVEARSCPGRQAAQSFTLRPVGFRDSLQVEVAYNCTCGCSTGLEPNSARCSGNGTYTCGLCECDPGYLGTRCECQEGENQSGYQNLCREAEGKPLCSGRGECSCNQCSCFESEFGRIYGPFCECDSFSCARNKGVLCSGHGECHCGECKCHAGYIGDNCNCSTDVSTCKAKDGQICSDRGRCVCGQCQCTEPGAFGETCEKCPTCPDACSSKRDCVECLLLHQGKPDNQTCHHQCKDEVITWVDTIVKDDQEAVLCFYKTAKDCVMMFSYTELPNGRSNLTVLREPECGSAPNAMTILLAVVGSILLIGMALLAIWKLLVTIHDRREFAKFQSERSRARYEMASNPLYRKPISTHTVDFAFNKFNKSYNGSV
What is the function of this protein?
Integrin alpha-V/beta-5 (ITGAV:ITGB5) is a receptor for fibronectin.  It recognizes the sequence R-G-D in its ligand.
What are the official names of this protein?
Integrin beta-5.
What is the protein family that this protein belongs to?
Belongs to the integrin beta chain family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: CYP9_CAEBR
Sequence: MSSLEKRVFLDMALDEKPIGRIEIKLFTSEAPKTCENFRALCTGEVGMAPNNKARLHYKGNEIHRVVKKFMIQGGDITDGDGRGGFSIYGRYFDDEKFVLKHSKPYLLSMANKGPNSNSSQFFITTAPAPHCNGKHVVFGEVIKGREVVDVLDNLEVDGKSKPIAKVRIFNSGELVKKKKPSKTKEELAALEERKRQEAKKDIPDIPKSWLYRDNEERESDFSSKTESSRVRSRSKSPSNNYETRRGHMANSRGDRNRRTQRADRKDDFGIAVRGRGGVQFRRVRYVTPEHWRRNAPSKWQQGSYTHPVDLQP
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imid ic peptide bonds in oligopeptides.  Thought to function as a catalyst in the folding and modification of cuticle collagens (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase 9, PPIase 9, Cyclophilin-9, Rotamase 9.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family.
Protein: PGK_CORA7
Sequence: MAFKTLDDLLAEGVSGRHVLVRSDFNVPLDDEGNITDSGRITASLPTIKALIEGGAKVILSAHLGRPKGEVNPKYSLAPVAEALSEALDQYVALAGDVSGEDAHERANGLNDGDVLLLENVRFDPRETSKDEAERGTFADELVALAADNGAFVSDGFGVVHRAQASVYDVAKRLPAYAGKLVQKEVETLAAVAEKPEHPYVVVLGGAKVSDKLGVIEALAGKADKVIIGGGMCYTLLAAQGYNVQDSLLQEDQIDNCKELLERFGDKIVLPVDLVAATEFDAQAENKVVALDGIPEGWQSLDIGPESVKKFDEVIASSKTVFWNGPMGVFEMEAFSKGTAGVAQSIIDATAKNGSFTVVGGGDSAASVRLLGLDEEGFSHISTGGGASLEFLEGKELPGVKVLEA
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14A_YEAST
Sequence: MSTDSIVKASNWRLVEVGRVVLIKKGQSAGKLAAIVEIIDQKKVLIDGPKAGVPRQAINLGQVVLTPLTFALPRGARTATVSKKWAAAAVCEKWAASSWAKKIAQRERRAALTDFERFQVMVLRKQKRYTVKKALAKA
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L14-A, Large ribosomal subunit protein eL14-A.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDI52_ORYSJ
Sequence: MAATTTRPLPLLLLLLLPPLLLLLLSFHAAAAAAAEEFPRDGRVIELDESSFEAALGAIDYLFVDFYAPWCGHCKRLAPELDEAAPVLAGLSEPIIVAKVNADKYRKLGSKYGVDGFPTLMLFIHGVPIEYTGSRKADLLVRNLNKFVAPDVSILESDSAIKSFVENAGTSFPMFIGFGVNESLIAGYGGKYKKRAWFAVAKDFSEDFMVTYDFDKVPALVSLHPKYKEQSVFYGPFEGSFLEDFIRQSLLPLTVPINTETLKMLDDDDRKVVLAILEDDSDETSSQLVKVLRSAANANRDLVFGYVGIKQWDEFVETFDISKSSQLPKLIVWDRNEEYEVVEGSEKLEEGDQASQISQFLEGYRAGRTTKKKVSGPSFMGFLNSLVSLNSLYILICVFALLGVMIYFTGQDDTPQVRRAHEE
What is the function of this protein?
Acts as a protein-folding catalyst that interacts with nascent polypeptides to catalyze the formation, isomerization, and reduction or oxidation of disulfide bonds.  May play a role in storage protein biogenesis (By similarity).
What are the official names of this protein?
Protein disulfide isomerase-like 5-2, OsPDIL5-2, Protein disulfide isomerase-like 7-1, OsPDIL7-1.
What is the protein family that this protein belongs to?
Belongs to the protein disulfide isomerase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: GRPE_STRZP
Sequence: MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFENKYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKGLGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKLHDRILRPAMVVVYN
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAFIP_HUMAN
Sequence: MLCPRAAFLVGSFHGVFPGPPASSHWEFWVPSTPVGAYFCPPQPQLTPPNTPKLVSEVEELYKSITALREKLLQAEQSLRNLKDIHMSLEKDVTAMTNSVFIDRQKCMAHRTCYPTILQLAGYQ
What is the function of this protein?
Acts as coactivator of MAFF transcriptional activity.  Inhibits cell growth and colony-forming efficiency.
What are the official names of this protein?
MaFF-interacting protein, Tektin-4 like protein PP5644.
What is the protein family that this protein belongs to?
Belongs to the tektin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Note=Interaction with MAFF induces its translocation from the cytoplasm to the nucleolus.
Protein: NADA_THEYD
Sequence: MVNRTVEEILALKKQRNAIILAHNYQREEVQEIADFVGDSLELSRQATKVDCDVIVFCGVHFMAETAAILNPDKTVLLPEIDAGCPMADTVDVEELKRWIDRYPYAPIVSYVNTTAEVKALSYACCTSANAPQIVKAVPFSSIIFVPDKNLADWVKKHVPEKDIIAWNGFCPTHHMIKKEDIIRAKKAHPDALVVVHPECRPEVIELADHVASTSGMVRFARAASQKEFIIGTEVGLLYRLKKENPDKVFYPIKKTMICPNMKITTLESILTALKENQYVIKVPEDIRIKAYEAVQRMLTLIS
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP_NEOSM
Sequence: MNLVPMVVDQTPRGERAYDIFSRLLKERVVFLTGPIEDGMASLIVAQLLFLEAENPDKDIFMYINSPGGVVTAGLSIYDTMQYIKPSVSTVCVGQAASAASLILASGAEGKRFALPHSRVMVHQPSGGVRGQATDMEIHVKEILQLKRMINEIYQKHTGETIKKIETLLERDTFLSPEEAKKVGIIDDIITQRKENSGKQE
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRCA_STRP3
Sequence: MITQRQNDILNLIVELFTQTHEPVGSKALQRTIDSSSATIRNDMAKLEKLGLLEKAHTSSGRMPSPAGFKYFVEHSLRLDSIDEQDIYHVIKAFDFEAFKLEDMLQKASHILSEMTGYTSVILDVEPARQRLTGFDVVQLSNHDALAVMTLDESKPVTVQFAIPRNFLTRDLIAFKAIVEERLLDSSVIDIHYKLRTEIPQIVQKYFVTTDNVLQLFDYVFSELFLETVFVAGKVNSLTYSDLSTYQFLDNEQQVAISLRQSLKEGEMASVQVADSQEAALADVSVLTHKFLIPYRGFGLLSLIGPIDMDYRRSVSLVNIIGKVLAAKLGDYYRYLNSNHYEVH
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor hrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.