PharMolix/UniProtQA huggingface dataset:
Protein: EPMA_ENT38
Sequence: MSETATWQPSASIPNLLKRAAIMTEIRRFFADRGVLEVETPCMSQATVTDIHLVPFETRFVGPGHSQGMNLYMMTSPEYHMKRLLAAGCGPVYQLCRSFRNEEMGRHHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCAGAETLSYQQVFQRHLEIDPLSADKTQLREAAAKLDLSNVADTEEDRDTLLQLLFAFGVEPHIGKDRPTFVYHFPASQASLAQISTEDHRVAERFEVYYKGIELANGFHELTDAREQQQRFDQDNRKRAARGLPQQPIDTNLLEALKAGLPDSSGVALGVDRLVMLALGAEQLADVIAFTVDRA
What is the function of this protein?
With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P).  Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P.
What are the official names of this protein?
Elongation factor P--(R)-beta-lysine ligase, EF-P--(R)-beta-lysine ligase, EF-P post-translational modification enzyme A, EF-P-lysine lysyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
Protein: 1A_PSVJ
Sequence: MAVSSSNLNELVASHGSSGLIASALVDKVASEQLEEQLNHQRRGLKVYIRNRLDVKESEVIRNRYGGKYDLHLSQQEHAPHGLAGALRLCETLDCLDAFPRTGLRQDLVLDFGGSWVTHFLRGHNVHCCSPCLGVRDKMRHTERLLSMRKAIINDPQTFEGRQPNFCTNPAEKCDVQAHYAISIHGGYDMGFEGLCRAMNAHGTTFLKGTMMFDGAMLFDDSGFIPELKCHWRKIKNAFSEKENASTFTSKLNLAVSGKTLIAFDFENESTMSYIHEWKNIKSFLTDQTFSYNGYTYGIERCVIYAGILTYKIIGVPGECPPEVIRHCVWFPSLKDYVGLKIPVSADLVEWKTVRLPLSTLRDTEEIAMRCYNDKKTWQDQFKIILGVLSSKSSTIVINGMAMQAGERVDINDYPYIGFAIMLHTKMKYDKLSLMYDAWGASIISQWWKAMTKPIRTFVRLVARTLFPTLRPRSESEFLVKLSTFVTFNDECITDMGEVWDVTANAAAVAAWAVSDGKQLVAEKEKALELANQQPVQNDSQPLTTVNLSTQDPPRSVTAILDPENPVVGQAELPEPPELKALSFQTRSPDTRLAERASAMLEYVAYEQQLHQNVISNLQRIWCSAGGDFVTNRLEGNLKFVFDTYFLTDPLVNVHFPSGRWMRPVPAGTKYMVGFNEKGLGPKMDSELYIVNADCVICNSDGLSSAVKALTAPTGTISLVDGVAGCGKTTAIKKLFQPATDLIVTANKKSAQDVRMALFGASDSKEACTFVRTADSILLNDVPEVSRVLVDEVVLLHFGQLCAVMSKLKAVRAICFGDSEQIAFGSRDASFDMRRSTILPDESSTSDTTFRSPQDVVPLVTRMAGKALPRGAKSKYSRWLSQSKVLNSVSQRCIPSVALVDMDESRFYITMTQADKAALITRAKELQMPSSFYDNKIKTVHESQGISEDHVTLVRLKSTKCDLFKSFPYCLVALTRHKVSFRYEFCGELKGDLIALVLATHSPLI
What is the function of this protein?
Involved in the virus replication.  Contains a helicase domain and a methyltransferase domain.  The methyltransferase domain is probably involved in viral RNA capping.  Involved in the formation of ER membrane spherular invaginations in which RNA replication complexes form (By similarity).
What are the official names of this protein?
Replication protein 1a.
What is the protein family that this protein belongs to?
Belongs to the bromoviridae replication protein 1a family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: TRML1_HUMAN
Sequence: MGLTLLLLLLLGLEGQGIVGSLPEVLQAPVGSSILVQCHYRLQDVKAQKVWCRFLPEGCQPLVSSAVDRRAPAGRRTFLTDLGGGLLQVEMVTLQEEDAGEYGCMVDGARGPQILHRVSLNILPPEEEEETHKIGSLAENAFSDPAGSANPLEPSQDEKSIPLIWGAVLLVGLLVAAVVLFAVMAKRKQGNRLGVCGRFLSSRVSGMNPSSVVHHVSDSGPAAELPLDVPHIRLDSPPSFDNTTYTSLPLDSPSGKPSLPAPSSLPPLPPKVLVCSKPVTYATVIFPGGNKGGGTSCGPAQNPPNNQTPSS
What is the function of this protein?
Cell surface receptor that may play a role in the innate and adaptive immune response.
What are the official names of this protein?
Trem-like transcript 1 protein, TLT-1, Triggering receptor expressed on myeloid cells-like protein 1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cytoplasm. Note=Sequestered in cytoplasmic vesicles in resting platelets (PubMed:15100151). Transported to the cell surface after stimulation by thrombin (PubMed:15100151). Soluble fragments can be released into the serum by proteolysis (PubMed:16505478).
Protein: PETD_PROM0
Sequence: MSTLKKPDLSDPKLRAKLAKGMGHNYYGEPAWPNDLLYIFPVVILGTIACVVGLAVLDPAMLGDKANPFATPLEILPEWYLYPVFQILRVVPNKLLGIALQTLIPLGLMILPFIENVNKFSNPFRRPIAMSVFLFGTFLTIYLGIGACLPIDKSLTLGLF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 4, 17 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetD subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: TRHO_VARPS
Sequence: MQEILNIAAYKFVAIDDSPVLREDLRERAQALGLMGTILLAPEGINLFLAGLPDAVRSFVAGLRADVRFADLETKESWSAAQPFRRMLVKLKREIIRMDHPAIQPAAGRAPGVDAPTLKRWLDQGHDDEGREIALLDTRNDFEVDEGSFDGAIDWRITKFTEFPPALKAHRADFAGKTVVSFCTGGIRCEKAAILMREEGIENVLQLEGGILKYFEEVGGAHYHGDCFVFDGRRALAPDLSARAADASARAAEDVGLSSGLKK
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: SPS2L_RAT
Sequence: MAELNTHVNVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWSMTGKKKNNKRKRSKSKQHQGNKDAKDKGERPEVGPLQPQAPLVQNGHMNGCEKDSSSPDSAREKLALTPREKKISILEEPPRAQRGITEGSRLLQQKMSLDGNPKAIHGPSERSDGLQWSAGQPCNPSKPKAKTSPVKSNAPAAHLEIKPDELAKKRGPNIEKSVKDLQRCTVSLTRYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMDILTARQKKAEELKRLTDLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQILICGEITHPKNNYSSRTPCSSLLPLLNTHAVASGKQGNFSRKSSGHNKPNEGKAANPKMVSGLPSTADACQQTMPTNKQQNGPSNQRRRFNPQYHNRLNGPAKSQGSGNEADPMVKSNNRHEHRRQPHNGFRPKNKGGAKNQEAPLGTKAPEAPPHSEKARRRQHAADNLETRPFRGNVGRVSQCNLCPTRIEVSTEATVLSVPAVTLVA
What are the official names of this protein?
SPATS2-like protein.
What is the protein family that this protein belongs to?
Belongs to the SPATS2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus.
Protein: PDE12_MOUSE
Sequence: MWRLPGRSALRGVRSVVERRSRAEAGTHEAVRAMERAVVRCVPSEPKLSLSFALADGSHKNMQRDQSEPLGRALSRIATNALKGHAKVAAAKKSRKNRAHSSGGAACEATGPEPVATCEPVVKLYYREEAVAEDVLNVDAWQDGAVLQIGDVKYKVERNPPTFTELQLPRYIMAGFPVCPKLGVEFGDPASSVFRWYKEVKPGAAEPGDSGPASSSHSSQPSAWIETGVDERVYTPCNADIGLRLRLHCTPGNGQRFGPSRELESLCPVEAGPGTCTFDHRHLYTKKVTEDSFIRTVSYNILADTYAQTEFSRTVLYPYCAPYALELDYRQNLIQKELTGYNADLICLQEVDRAVFSDSLVPALEAFGLEGVFRIKQHEGLATFYRKSKFRLLSQHDISFQEALKSDPLHKELLEKLALNPLAQEKVLQRSSVLQISVLQSTTDSSKKICVANTHLYWHPKGGYIRLIQMEVALVHIRHVSRDLYPGIPVIFCGDFNSTPSTGMYHFVISGSIAEDHEDWASNGEEERCSMPLSHCFKLKSACGEPAYTNYVGGFHGCLDYIFIDLNTLEVEQVIPLPSHEEVTTHQALPSVSHPSDHIALVCDLKWK
What is the function of this protein?
Enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system.  Degrades triphosphorylated 2-5A to produce AMP and ATP.  Also cleaves 3',5'-phosphodiester bond of oligoadenylates.  Plays a role as a negative regulator of the 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs).  Suppression of this enzyme increases cellular 2-5A levels and decreases viral replication in cultured small-airway epithelial cells.
What are the official names of this protein?
2',5'-phosphodiesterase 12, 2'-PDE, 2-PDE, Mitochondrial deadenylase.
What is the protein family that this protein belongs to?
Belongs to the CCR4/nocturin family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: PANB_BACCN
Sequence: MKTKTDFLRMKQKGEPITMLTAYDYPSAKLVEEAEVDMILVGDSLGMVVLGYDSTVPVTVEDMIHHTKAVRRGAKDTFVVTDMPFMSYHVSLAETMHHARRIVQEGGAHALKVEGAGEVISTIHYLTNAGIPVVAHLGLTPQSVGILGGYKVQGKDAESAKQLIADAKKCEDAGAIALVLECVPMQLAKIISDELTIPTIGIGAGKDVDGQVLVYHDLISYGVNRVPKFVKQYTAVQDEIVRGISQYVAEVKTRQFPEDQYSFTMKEEEYVALYGGKQG
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IBPA_ECOBW
Sequence: MRNFDLSPLYRSAIGFDRLFNHLENNQSQSNGGYPPYNVELVDENHYRIAIAVAGFAESELEITAQDNLLVVKGAHADEQKERTYLYQGIAERNFERKFQLAENIHVRGANLVNGLLYIDLERVIPEAKKPRRIEIN
What is the function of this protein?
Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress.  Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE.  Its activity is ATP-independent.
What are the official names of this protein?
Small heat shock protein IbpA, 16 kDa heat shock protein A.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATC_BURMA
Sequence: MALTLTDVTRIAHLARLEMADADAERTLTQLNEFFGLVEQMQAVDTTGIAPLAHPIEQILEVAQRLREDAVTEHVNRDDNQRPAPAVQDGLYLVPKVIE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: MTNW_BACLD
Sequence: MSELLATYILADPGCDAEKRAEQIAIGLTVGSWTDLPLLKQEQLKKHKGRVVNVEETESELGEKQATVTIAYPEANFTNDIPAVLTTVFGKLSLDGKIKLADLEFSRSFKQSLPGPKFGVYGIRKKIGEFERPLLMSIFKGVIGRDMEDLKEQLRQQALGGVDLIKDDEILFETGSAPFEKRITEGKKVLEEAFEETGRKTLYAVNLTGRTMELKAKARKAAELGADVLLLNVFAYGLDVLQSFAEDDDIPLPIMAHPAVSGALTSSPHYGFSHSLLLGKLNRYAGADFSLFPSPYGSVALPKRDALAIYDECTKEDVFKPTFAVPSAGIHPGMVPLLMKDFGIDHIINAGGGIHGHPNGAAGGGRAFRAVIDAVLEAEPVEEKAKRSPDLKLALEKWGRVEVSV
What is the function of this protein?
Catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P).
What are the official names of this protein?
2,3-diketo-5-methylthiopentyl-1-phosphate enolase, DK-MTP-1-P enolase, RuBisCO-like protein, RLP.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type IV subfamily.
Protein: ATPD_LACLA
Sequence: MTKVNSQKYSKALLEVAQEKGQLEAILSEVSEMIQLFKEDNLVAFLSSEVYSFSAKSELIDTLLQTSSEVMSNFLNTVRSNGRLGDLGEILDETKNAADDMFKIADVGVVSSIALTNAQIEKFTAMAKAKFDLNEVTVINTVNEKILGGFIVNSRGKIIDASLKTQLAKIAAEIL
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: Y3048_POLSJ
Sequence: MLLTLPDILSPQDLQAARQLLIDAPWADGRDSAGAQARQVKNNAQLPHDCEAARAIGTMVVGGLERSALFLTAALPKKIFTPRINRYSGAANHYGNHVDSAIRTMAGSGQRVRTDVSCTVFLSEPDDYEGGELTIADTYGEQRIKLPAGHAVLYPGTSLHQVQPVTRGQRLACFFWVESLVRGNEQRRLLFDMDMALMQLRQEHGESQATVALTGAYHNLLRMWADT
What are the official names of this protein?
PKHD-type hydroxylase Bpro_3048.
Protein: CU64_LOCMI
Sequence: GLLGLGYGGYGGYGGYGGYGHGLALAAAPAAIAAPAVVAAPAIAHAPAVAVAPAVAHAPAAVSTVSQVSYGTTHYAPAVAKVAAIAAPVAVAAPAIAAAPAVGLGYGGYGHGLSLGYGHGLGLGYAAAPALSLGYGGYGHGLGYGGYGYGHH
What is the function of this protein?
Component of the cuticle of migratory locust which contains more than 100 different structural proteins.
What are the official names of this protein?
Cuticle protein 64, LM-ACP 64, LM-64.
Protein: MNMG_LEPIC
Sequence: MIESKNQSFFPNRFDCVVVGAGHAGSEAAYISSKGGARTLLITMNLDTIGQMSCNPAIGGIAKGHMVREVDALGGIMGKMIDNTGIQFKMLNTSKGPSVWAPRAQAEKKEYQLKVKHTLEAEKNLSIRQDTVEELIIENDQVIGVRTGRGFEIFTNHVILTTGTFLSSLVHIGTYQNENGRMCEPTVKGLSKSLAKYNLKLGRLKTGTPPRIHKNSVDLSVLTIQEGDSNPSPFSFSTDKITRKQIPCFITYTNAETHKLIHENLNLSPMYSGQIQSTGPRYCPSIEDKVVRFADRERHQVFLEPEGYETSEIYLNGVSTSLPEEVQWKLVRSLKGLENAEIVRPGYAIEYDYVDPTELKPTLETKKIKGLYHAGQINGTTGYEEAAAQGLVAAYSVLHSLRNLTPLLFKRSESYIGVLIDDLVHKGVEDPYRMFTSRAEHRLLLRQDNADQRLMKYGYDLGLVDQKSYDCMKEKYERVNSVREKIYQIPLKPSDKFQNLLDQKGITNYKFGMKLDSFLKRPEIKIKDIEFMIPEVSSWSDLEKSILEMEIKYEGYIKRELETIQWKNKYLDLAIPEDINYEMIAGLKKEAIQKLKSHKPMTLEKASQISGVDPSDVDLILYHIKGKKKQEVEIF
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_RENSM
Sequence: MTMTDPVADMLTRLRNANSAHHDSVKMPFSKLKGHVADILKAEGYIASWKVEDAEVGKSLTIDLKFGPNRERSIAGIRRISKPGLRVYAKSTNLPKVLGGLGVAILSTSSGLLTDRQAAKKGVGGEVLAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: HBBZ_MOUSE
Sequence: MVHFTAEEKAAITSIWDKVDLEKVGGETLGRLLIVYPWTQRFFDKFGNLSSALAIMGNPRIRAHGKKVLTSLGLGVKNMDNLKETFAHLSELHCDKLHVDPENFKLLGNMLVIVLSTHFAKEFTPEVQAAWQKLVIGVANALSHKYH
What is the function of this protein?
This is an embryonic beta-type chain.
What are the official names of this protein?
Hemoglobin subunit beta-H1, Beta-H1-globin, Hemoglobin beta-H1 chain, Protein Z.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RR7_BETVU
Sequence: MSRRGTVEEKTAKSDPIYRNRLVNMLVNRILKHGKKSLAYQILYRAVKKIQQKTETNPLSVLRQAIRGVTPDIAVKARRVGGSTHQVPIEIGSTQGKALAIRWLLGAARKRPGRNMAFKLSSELVDAAKGSGDAIRKKEETHRMAEANRAFAHFR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast. Mitochondrion.
Protein: CCD1P_DROME
Sequence: MNTLSSARSVAIYVGPVRSSRSASVLAHEQAKSSITEEHKTYDEIPRPNKFKFMRAFMPGGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFNTKDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKNRDNSDALTLFQTSRDIFRLTFKLDIQPSMWKIISTPTYRKMKRTLNDSLNVAQKMLKENQDALEKRRQAGEKINSNSMLERLMEIDPKVAVIMSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPTKDSLLNEENMKDMPYLRAVIKETLRYYPNGLGTMRTCQNDVILSGYRVPKGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPETGKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTMFVMEPAITFPFKFTDIEQ
What are the official names of this protein?
Probable cytochrome P450 12d1 proximal, mitochondrial, CYPXIID1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Mitochondrion membrane.
Protein: ECTA_CHRSD
Sequence: MTPTTENFTPSADLARPSVADTVIGSAKKTLFIRKPTTDDGWGIYELVKACPPLDVNSGYAYLLLATQFRDTCAVATDEEGEIVGFVSGYVKRNAPDTYFLWQVAVGEKARGTGLARRLVEAVLMRPGMGDVRHLETTITPDNEASWGLFKRLADRWQAPLNSREYFSTGQLGGEHDPENLVRIGPFEPQQI
What is the function of this protein?
Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.
What are the official names of this protein?
L-2,4-diaminobutyric acid acetyltransferase, DABA acetyltransferase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. EctA subfamily.
Protein: RUVC_PROM0
Sequence: MRIIGIDPGLARVGYGIIEIENERKILLDCGVIETGKDKKEEDRLYEIFQDLNELINHWNPTSAAVEKFFFYRSSTTISVVQARGVIMMVLASKKINVSEYSPAQIKLTIAGSGKASKKDILDAVMYNLDLNKPPKPDDSADALAIALTKLNEDGFN
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: MSRB_YERP3
Sequence: MAKELNPTENIEKLSDIQRYVTQERGTEAPFTGKLLHNKRDGVYQCLCCHQPLFISESKFDSGCGWPSFYQPIDADSIRYIDDYSHNMHRIEIRCGNCDAHLGHVFPDGPQPTGERYCINSASLNFVDDQNGEQTAG
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: DCAM_RAT
Sequence: MEAAHFFEGTEKLLEVWFSRQQSDASQGSGDLRTIPRSEWDVLLKDVQCSIISVTKTDKQEAYVLSESSMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQSFFYSRKNFMKPSHQGYPHRNFQEEIEFLNAIFPNGAAYCMGRMNSDCWYLYTLDLPESRVINQPDQTLEILMSELDPAVMDQFYMKDGVTAKDVTRESGIRDLIPGSVIDATLFNPCGYSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQTSYDDLIRKVVEVFKPGKFVTTLFVNQSSKCRTVLSSPQKIDGFKRLDCQSAMFNDYNFVFTSFAKKQQQQS
What is the function of this protein?
Essential for biosynthesis of the polyamines spermidine and spermine.  Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic AdoMetDC family.
Protein: Y1547_CROS8
Sequence: MEMDLNNRLTEDETLEQAYDIFLELAADNLDPADIILFNLQFEERGGAELFDPSEEWLSHVDYDLNPDFFSEVVIGLAEKDGDEITDVFARVLLCREKDHKLCHILWRE
What are the official names of this protein?
UPF0263 protein ESA_01547.
What is the protein family that this protein belongs to?
Belongs to the UPF0263 family.
Protein: CEMA_CHLRE
Sequence: MYTFIYFKNPKHFNLSQPSRCTAQPFISTRNRPLSCPIPTVQPIYVTHGIILPILKGTLISQRGVNIVPFVSKRDSSYYTDKDKVVSITYEEIGLFPRSFSRVLDRFLKQLFSDVDNLVIQEYRFYRYLFLTTIKTIFILFFVPFLVNFAAKNYIVKPITEYFWNTSHPEIFLNSYEQKRAFVELAKFEEKIYFETLVESHSHHQTHRDSKPLRENGIYFPDGEFLDNANLLSTPRSINSNTFLKQNIDISLREEKPLTLVQGVNLLEEKKELNIPLAQENIAYNNQSIPQTSFGQGNFSSLFTGDREGEETAKQNLLSQRVIGANLRQIYLPSAEGEMLPSIRGSLDSIKNKDISKIYQEKTIELATYYNNHSIEAITNFFADLLSLFTLLYLLITLEIQINITKSFLLEVFFGLDDSKKSLLILLITDLLVGYHSSNLWELFFEFIFNHYGIPESQTGIFLLVATLPVLLDVLFKYLIFRHLNRSSPATVATYQAIIE
What is the function of this protein?
May be involved in proton extrusion.  Indirectly promotes efficient inorganic carbon uptake into chloroplasts.
What are the official names of this protein?
Chloroplast envelope membrane protein.
What is the protein family that this protein belongs to?
Belongs to the Cema family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: AROD_SYNFM
Sequence: MSLAHSLICGCLMRESTEDTARFLEYPGIGLVEWRLDALHGIHTRNGLDEALAGLSLPGRHPVIATVRPERFRGGFRGTEEARIRALERTVRAGAEWIDLEDDLPEDVLSPFRDSAARVVISHHDFDGTPASDPLKHRVEHLATLGAHVLKIATYARTVEDNLRVLELIPFARKQFGAETIAFCMGPTGRWSRLACLLMGSPWTYVRFPELPASAPGQFTVAQMQTLLEIVGAG
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: RUVB_MYCA1
Sequence: MTAHDADWSDRDVSGALVPGEGDIDVSLRPRSLREFIGQPRVREQLQLVIEGAKNRGGTPDHILLSGPPGLGKTSLAMIIAAELGSSLRVTSGPALERAGDLAAMLSNLVEHDVLFIDEIHRIARPAEEMLYLAMEDFRVDVVVGKGPGATSIPLEVAPFTLVGATTRSGALTGPLRDRFGFTAHMDFYEPAELQQVLARSAGILGIELGAEAAEEIARRSRGTPRIANRLLRRVRDFAEVRADGVITRDVAKAALAVYDVDELGLDRLDRAVLTALTRSFGGGPVGVSTLAVAVGEEAATVEEVCEPFLVRAGMVARTPRGRVATAQAWTHLGMVPPAGAAGLGQPGLFD
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: 53DR_STAAN
Sequence: MTRKSIAIDMDEVLADTLGEIIDAVNFRADLGIKMEALNGQKLKHVIPEHDGLITEVLREPGFFRHLKVMPHAQEVVKKLTEHYDVYIATAAMDVPTSFSDKYEWLLEFFPFLDPQHFVFCGRKNIVKADYLIDDNPRQLEIFTGTPIMFTAVHNINDDRFERVNSWKDVEQYFLDNIEK
What is the function of this protein?
Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides.
What are the official names of this protein?
Putative 5'(3')-deoxyribonucleotidase.
What is the protein family that this protein belongs to?
Belongs to the 5'(3')-deoxyribonucleotidase family.
Protein: CH602_CERS4
Sequence: MSAKEVRFGTDARGRMLKGINTLADTVKITLGPKGRNVILDTSYGAPRITKDGVTVAREIELSDRFENVGAQMVKEVASRTNEEAGDGTTTATVLAQAIAKEGMKAVAAGMNPMDLKRGIDRAVAIVIAEIRSMSRPVGDSAEIAKVGALSANGEAAIGRQIADAMAKVGTAGVIKVEENKGLETETEVVEGMQFDRGYLSPYFITHAQKMVVELDDCAILLHEGKLTSLASMVPLLEAVVQAEKQLLVVAEDVEGEALTTLVVNKLRGGLKVAAAKAPGFGDGRAAMLEDLAVLTGAHLISAELGTKLETVTLDMLGFAKKVVLTKDSTILIDSAGDKAAIASRIGQIRNQIEDTTSAYNKEKLQERLARLAGGVAVIRVGGATEIEVKERRDRVEDTLNATRAAVQEGVVPGGGAALIHAGKALAGLKGDNPDQDAGIKIIRRAIQAPLRQIADNAGIDGSVVAGKVIENDSATFGFDAQLETYGDMLQAGIIDPTKVVRIALEDAASIAGLLITTEVIIAHKPERGERMSQMDEMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.