PharMolix/UniProtQA huggingface dataset:
Protein: SUCC_CERS4
Sequence: MNIHEYQAKALLRSYGAPVSDGRVVLKADEAKSAAGELGGPLWVVKAQIHAGGRGKGKFKEPEAGEKGGVRLAKSVGEAAELAKQMLGRTLVTHQTGPAGKQVNRIYIEEGSDIARELYLALLVDRGTSRISFVVSTEGGMDIEEVAASTPEKIVSFSVDPASGLSDFHGRRVAFALGLEGAQVKQCVQLVKNLYRAFVEKDMEMLEINPLIVMTDGNLKVLDAKVGFDNNALYRQSDVMALRDETEEDPKELAASKFDLNYIALDGEIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGGGATKEKVTEAFKIITSDPNVKGILVNIFGGIMRCDIIAEGIIAAVKEVGLQVPLVVRLEGTNVEKGKEIIANSGLNVIAGDNLSDAAQKIVKAVKG
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: TUSC_SALDC
Sequence: MKRIAFVFSTAPHGSASGREGLDALLATSALTEALGVFFISDGVFQLLPGQKPDAVLARDYIATFKLFDLYDIDQCWICAASLRERGLENVNFVVDATPLEPVALRRELGNYDVILRF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
What are the official names of this protein?
Protein TusC, tRNA 2-thiouridine synthesizing protein C.
What is the protein family that this protein belongs to?
Belongs to the DsrF/TusC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYDE_METM7
Sequence: MDDSKRILITKVLKNEVTEALGCTEVGLIGYAISLCNISYPFSIEKIEVTLNNGSFKNAYAVGVPNTKKYGILPAVVGGLLGNSKNKLLIFNDIKYDQKLEDFIKKRLEVKVLDGPLYCGVKIKDTSGKFFESLIKDNHLNVVIPKIEKEKISLEITDFEKEEYKSLELTDFLNYLDEIPEEIINLVEKTIYTNKNLIKGDFLNYGNDILSNMVNKTTSACNTRMTGENMPAMSVAKSGNMGLMATLPIISYDNLTENNFEKLKKSLLLAMLVTIYSTYNSSYLSSMCGCVSKGGMGAVIGLCYYKNGKNLKKLNSAARAFTANLPGIICDGGKVGCALKLASGCFAAYSSLYVEISHENGIVGKNFKECVQNISKISKAMGDLDCDIVKIMSKKEM
What is the function of this protein?
Catalyzes the cleavage of L-cysteine to form 2-aminoprop-2-enoate and sulfide.  The former then spontaneously hydrolyzes to pyruvate and NH(3).  May be responsible for the production of sulfide required for the biosynthesis of iron-sulfur centers in this archaea.
What are the official names of this protein?
L-cysteine desulfidase, L-cysteine desulfhydrase.
What is the protein family that this protein belongs to?
Belongs to the L-cysteine desulfidase family.
Protein: ATP61_SYNC1
Sequence: MTHPFLFLKWLVEHFTQGTSLENLEHYGFLVHVTHAWLIMLLLTGVALLLKRRLSEVPGGLQNLVEIVLVELGRLADETMGPKGRRYFPLIATLALFILFSNLIALIPGFAPPTANLNTNAALALAVFGMTHVVGVREHGLKYFKHFVGPVWWLAPLILPIEIIGHLARPLSLALRLFGNMYGHEIVLVIFFTLVPLLLPIPMMLMGILVAFIQTFVFTLLAMIYIAGALEEAH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a 1, ATP synthase F0 sector subunit a 1, F-ATPase subunit 6 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NPRL3_MOUSE
Sequence: MGDNTSPISVILVSSGSRGNKLLFRYPFQRSQEHPASQTNKPRSRYAVNNTGEHADDQDGDSRFSDVILATILATKSEMCGQKFELKIDNVRFVGHPTLLQHALGQVSKTDPSPKREAPTMILFNVVFALRANADPSVINCLHNLSRRIATVLQHEERRCQYLTREAKLILALQDEVSAMADANEGPQSPFQHILPKCKLARDLKEAYDSLCTSGVVRLHINSWLEVSFCLPHKIHYAASSLIPPEAIERSLKAIRPYHALLLLSDEKSLLSELPIDCSPALVRVIKTTSAVKNLQQLAQDADLALLQVFQLAAHLVYWGKAVIIYPLCENNVYVMSPNASVCLYSPLAEQFSRQFPSHDLPSVLAKFSLPVSLSEFRSPLAPPAQETQLIQMVVWMLQRRLLIQLHTYVCLMASPSEEEPRLREDDVPFTARVGGRSLSTPNALSFGSPTSSDDMTLTSPSMDNSSAELLPSGDSPLNKRMTENLLASLSEHERAAILNVPAAQNPEDLRMFARLLHYFRGRHHLEEIMYNENTRRSQLLMLFDKFRSVLVVTTHEDPVIAVFQALLT
What is the function of this protein?
As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway.  The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling.  The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway.
What are the official names of this protein?
GATOR complex protein NPRL3, Nitrogen permease regulator 3-like protein.
What is the protein family that this protein belongs to?
Belongs to the NPR3 family.
What are the subcellular locations of this protein?
Lysosome membrane. Note=Localization to lysosomes is amino acid-independent.
Protein: IPA3_SHIFL
Sequence: MSIMLPINNNFSLSQNSFYNTISGTYADYFSAWDKWEKQALPGENRNEAVSLLKECLINQFSELQLNRLNLSSLPDNLPPQITVLEITQNALISLPELPASLEYLDACDNRLSTLPELPASLKHLDVDNNQLTMLPELPALLEYINADNNQLTMLPELPTSLEVLSVRNNQLTFLPELPESLEALDVSTNLLESLPAVPVRNHHSEETEIFFRCRENRITHIPENILSLDPTCTIILEDNPLSSRIRESLSQQTAQPDYHGPRIYFSMSDGQQNTLHRPLADAVTAWFPENKQSDVSQIWHAFEHEEHANTFSAFLDRLSDTVSARNTSGFREQVAAWLEKLSTSAELRQQSFAVAADATESCEDRVALTWNNLRKTLLVHQASEGLFDNDTGALLSLGREMFRLEILEDIARDKVRTLHFVDEIEVYLAFQTMLAEKLQLSTAVKEMRFYGVSGVTANDLRTAEAMVRSREENEFTDWFSLWGPWHAVLKRTEADRWAQAEEQKYEMLENEYSQRVADRLKASGLSGDADAEREAGAQVMRETEQQIYRQVTDEVLALRLSENGSQLHHS
What is the function of this protein?
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues.  This protein is an E3 ubiquitin ligase that interferes with host's ubiquitination pathway.  Synthesizes a 'Lys-48'-linked ubiquitin chain, which requires non-covalent binding between ubiquitin and the host ubiquitin-conjugating enzyme UBE2D1.
What are the official names of this protein?
E3 ubiquitin-protein ligase ipaH3, RING-type E3 ubiquitin transferase ipaH3.
What is the protein family that this protein belongs to?
Belongs to the LRR-containing bacterial E3 ligase family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Note=Secreted via Mxi-Spa type III secretion system (TTSS), and delivered into the host cytoplasm.
Protein: TRPE_BUCPS
Sequence: MKNRRYEVEILQIEGIYQSDPTTIFNQLCNKKKCTLLLESAEIDKKHALESMIIIDSALRISSLDNIVTIEALTENGKSLLFKLDLLLPLTVKNVLFENSRRLIFPFINHEIDEDKKLRSVSIFDTFRLLIKTMKIPKNLTKSMFFGGLFSYDLVNNFEKLPILNRNQKCPDLCFYLAETLLILDHKKKNCIIQSSLFNRKSSEKNRLKKNLQEIKTKLTQNVPKIEHRKIDQISLKCNLTDKEYIKIIKKMKQSIKKGDIFQVVPSRKFYLPCISSLSAYQRLKQSNPSPYMFFMQDSDFTLFGASPESSLKYDSKSKKIEIYPIAGTRPRGKTENGLIDLDLDSKIELEMRMNEKELSEHLMLVDLARNDLARICEPGSRYVASLTKVDRYSCVMHLVSKIVGRLKSNLDIFHAYCACMNMGTLTGAPKIKAMELISKFEKERRGSYGGSIGYFTESNNFDTCIIIRSAYVENNLATVQAGAGIVLDSVPQEEANESRNKAQAVIQAIIYAHSSREVV
What is the function of this protein?
Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan.  In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate.  In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia (By similarity).
What are the official names of this protein?
Anthranilate synthase component 1, AS, ASI.
What is the protein family that this protein belongs to?
Belongs to the anthranilate synthase component I family.
Protein: CM1_PETHY
Sequence: METQLLRFPSHTITSSITTNSSRNTTPFLPHKKWSHFVKFQLVNSSSSIKHGIRPLQASATSLGLGNKNRVDETESYTLDGIRHSLIRQEDSIIFSLVERAQYCYNAETYDPDVFAMDGFHGSLVEYIVRETEKLHATVGRYKSPDEHPFFPKVLPEPVLPPMQYPKVLHPIADSININVKIWEMYFENLLPRLVKEGDDGNYGSTAVCDTICVQALSKRIHYGKFVAEAKYRASPEVYNAAIRAQDRNGLMDLLTYPAVEEAIKRRVEIKTRTYGQELHINGPENGGDPVYKIKPSLVAELYGDWIMPLTKEVQVQYLLRRLD
What is the function of this protein?
Component of the floral volatile benzenoid/phenylpropanoid (FVBPs) biosynthetic pathway (PubMed:19811620).  Mediates the conversion of chorismate to prephenate, thus coupling metabolites from the shikimate pathway to the synthesis of FVBPs in the corolla (PubMed:19811620).
What are the official names of this protein?
Chorismate mutase 1, chloroplastic, PhCM1.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: MTLD_PASMU
Sequence: MKALHFGAGNIGRGFIGKLLADSGIQVIFADVNDHVIEQLKTQRAYPVKIVGDRLNVIETVSNVTGVNSKNEADIIACFTEVDLVTTAVGPNVLKIISSTIAKGLSARFRAGNTRPLNIIACENMVRGTSFLKDNVFSYLTPEEQQQAEAQIGFVDSAVDRIVPPVQFDPANPLLVTVEEFSEWIVDKTQFKGTIPAITGMEQTDNLMAFVERKLFTLNTGHATTAYLGKLKGHQFVKDSIDDPDIREAVKATMQESGAVLIKRYGFDPHAHAAYIEKILKRFANPYLQDDVDRVGREPLRKLSYNDRLIKPLRGTLEYGLPNQHLIQTIASALAYRNESDPQAVELAQLLQQDTLESAVKKITELTESNIVQQIVTAYNALQKN
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: METK_NOVAD
Sequence: MRTDYLFTSESVSEGHPDKVSDQISDAIVDLFLSKDPEARIACETLTTTQLVVLAGEIRCKGVYENGEWAPGAQDEIEKTVRDTVKRIGYEQDGFHWERLEFINRLHGQSAHIAQGVDAADNKDEGAGDQGIMFGYATDETPDLMPATLYYSHKILERMAADRHSGAAPFLEPDAKSQVTLRYEGSLPVAATAVVVSTQHAPGYDEGGKEAELHEYVKRVVAEVIPPVLLRETKYYINPTGSFEIGGPDGDAGLTGRKIIVDTYGGAAPHGGGAFSGKDPTKVDRSAAYITRYLAKNVVAAGLATRCTIQIAYAIGVSEPLSLYVDTHETGTVGDDKIEQAILGIAKLGGLTPRAIRTHLGLNKPIYRPTAAYGHFGRKADGDFFPWERLDLVDDLKAAFA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VF233_ASFK5
Sequence: MILIASPFSLAHLEYLNTWHAHIKNIAQQHGLDIKVAIVISNTHLNNFLPVSTPLNIECITFPGCGIKEIDLLWARIKLFQHYCAIGARLLWLVSADIRPSVSTWPAIADSLKKGADAVVVPYPSRWNNLIPTVIKEIVVRQKKCLVAVDAHHLDTDTQIVGAGMGCIVLTLKALMVRLSIGKQPIKILWPDLHGTAEGIPLEGVEVGWFLNAYAHKLNIRCLGRDYIAQHLN
What are the official names of this protein?
Uncharacterized protein H233R, pH233R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus H233R family.
Protein: FPG_MYCMM
Sequence: MPELPEVEVVRRGLQDHVVGKTMTAVRVHHPRAVRRHEAGPADLTARLLGARISGTDRRGKYLWLTLDAGAPTTGRDDPDTALVVHLGMSGQMLLGGVPRAEHVRISAVLDDGTVLSFADQRTFGGWQLADLVSVDGSVVPAPVAHLARDPLDPLFDVDSVIKVLRGKHSEIKRQLLDQQVVSGIGNIYADEALWRAKVHGARVAATLTRRQLGAVLDAAADVMREALAKGGTSFDSLYVNVNGQSGYFDRSLDAYGREGEHCRRCGAVMRREKFMNRSSFYCPRCQPRPRR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: RL10_CHICK
Sequence: PRCYRYCKNKPYPKSRFCRGVPDPKIRIFDLGRKKAKVDEFPLCGHMVSDEYEQLSSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINKMLSCAGADRLQTGMRGAFGKPQGTVARVHMGQVIMSIRTKAQNKEHVVEALRRAKFKFPGRQKIHISKKWGFTKFNADAFEEMVAQKRLIPDGCGVKYVPGRGPLDRWRALHAA
What is the function of this protein?
(Microbial infection) Seems to bind to the leucine zipper of viral and cellular JUN.
What are the official names of this protein?
60S ribosomal protein L10, Jun-binding protein JIF-1, Ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: RL32_NITEU
Sequence: MAVQQNKKSPSKRGMHRSHDALTNPPLAIEPTTGEIHLRHHISPNGYYRGKKVIKTKNDD
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: PAN_PYRFU
Sequence: MSEDEAQFHGNYDDYVTYLKRRIRQLELQVRMLEADKERLERELSRLRSEMSRLRQPPAFAGSVIEVLDDDRAIVQNYNGPRFVVRIAPWIDKSKLRPGTRVALDQRTMAIIEILPASKDPAVLGFEVVERPNVTYNDIGGLKKQLQELREAIELPLKHPELFEEVGIDPPKGVLLYGPPGCGKTLMAKAIAHEVNATFIRVVGSELVRKYIGEGARLVHELFELAKEKAPTIIFIDEIDAIGAKRLDETTGGEREVNRTLMQLLAEMDGFDPRGNVKVIAATNRPDILDPALLRPGRFDRLIEVPLPDFEGRLEILKVHTRRMKLRGVDLRLIAELTEGASGADLKAIATEAGMFAIRERRTYVTQEDFLKAIDKVLGNEKKIIQQIMSHEVIYG
What is the function of this protein?
ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle.  Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis.  Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.  Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
What are the official names of this protein?
Proteasome-activating nucleotidase, PAN, Proteasomal ATPase, Proteasome regulatory ATPase, Proteasome regulatory particle.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2153_ENT38
Sequence: MTEPLKPRIDFPGTLEQERAEAFKAAQAFSGPQAENFAPAVAEELLSDEGPAEAVVEAALRPKRSLWRKMVTAGLTLFGISVVGQGVQWTMNAWQTQDWVALGGCAAGALIIGAGVGSVATEWRRLWRLRQRAHERDEARDLFHSHATGKGRAFCEKLASQAGIDQSHPALQRWYAAIHETQSDREIVSLYASIVQPVLDSQARREISRSAAESTLMIAVSPLALVDMAFIAWRNLRLINRIARLYGIELGYYSRLRLFRLVLLNMAFAGASELVREVGMDWMSQDLAARLSTRAAQGIGAGLLTARLGIKAMELCRPLPWLNDDKPRLGDFRRELIGQLKETLSKKPQ
What are the official names of this protein?
UPF0283 membrane protein Ent638_2153.
What is the protein family that this protein belongs to?
Belongs to the UPF0283 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PURNU_MYCBO
Sequence: MLASTRHIARGDTGNVSVRIRRVTTTRAGGVSAPPFDTFNLGDHVGDDPAAVAANRARLAAAIGLPGNRVVWMNQVHGDRVELVDQPRNTALDDTDGLVTATPRLALAVVTADCVPVLMADARAGIAAAVHAGRAGAQRGVVVRALEVMLSLGAQVRDISALLGPAVSGRNYEVPAAMADEVEAALPGSRTTTAAGTPGVDLRAGIACQLRDLGVESIDVDPRCTVADPTLFSHRRDAPTGRFASLVWME
What is the function of this protein?
Purine nucleoside enzyme that catalyzes the phosphorolysis of adenosine and inosine nucleosides, yielding D-ribose 1-phosphate and the respective free bases, adenine and hypoxanthine.  Also catalyzes the phosphorolysis of S-methyl-5'-thioadenosine into adenine and S-methyl-5-thio-alpha-D-ribose 1-phosphate.  Also has adenosine deaminase activity.
What are the official names of this protein?
Purine nucleoside phosphorylase BQ2027_MB2173C, Adenosine deaminase BQ2027_MB2173C, S-methyl-5'-thioadenosine phosphorylase BQ2027_MB2173C.
What is the protein family that this protein belongs to?
Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.
Protein: RIMM_PSEAE
Sequence: MPTPADDLVVIGKIVSVYGIRGEVKVYSFTDPLDNLLDYRRWTLRRDGEIRQAELVRGRLHGKVLAAKLKGLDDREEARTFTGYEICIPRSELPSLEEGEYYWHQLEGLKVIDQGRQLLGVIDHLLETGANDVMVVKPCAGSLDDRERLLPYTGQCVLSIDLAAGEMRVDWDADF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_PHOV8
Sequence: MEIILKEDVVNLGYKNDIVTVKSGYGRNYLIPTGKAVIASPSAKKMLAEELKQRAHKLEKIKKDAEAMAEQLKDVTLTIATKVSATGTIFGSVSNIQIAEELEKLGHKVDRKIIVVKDAVKEVGSYKAIVKLHKEVSVEIPFEVVAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: ISM1_HUMAN
Sequence: MVRLAAELLLLLGLLLLTLHITVLRGSGAADGPDAAAGNASQAQLQNNLNVGSDTTSETSFSLSKEAPREHLDHQAAHQPFPRPRFRQETGHPSLQRDFPRSFLLDLPNFPDLSKADINGQNPNIQVTIEVVDGPDSEADKDQHPENKPSWSVPSPDWRAWWQRSLSLARANSGDQDYKYDSTSDDSNFLNPPRGWDHTAPGHRTFETKDQPEYDSTDGEGDWSLWSVCSVTCGNGNQKRTRSCGYACTATESRTCDRPNCPGIEDTFRTAATEVSLLAGSEEFNATKLFEVDTDSCERWMSCKSEFLKKYMHKVMNDLPSCPCSYPTEVAYSTADIFDRIKRKDFRWKDASGPKEKLEIYKPTARYCIRSMLSLESTTLAAQHCCYGDNMQLITRGKGAGTPNLISTEFSAELHYKVDVLPWIICKGDWSRYNEARPPNNGQKCTESPSDEDYIKQFQEAREY
What is the function of this protein?
Acts as an angiogenesis inhibitor.
What are the official names of this protein?
Isthmin-1.
What is the protein family that this protein belongs to?
Belongs to the isthmin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRMD_CARHZ
Sequence: MKIDILTLFPEMFYGPLNSSILKKAQEKGIITINYINIRDFTTDRHHQADDKPYGGGAGMVMKVEPIIKAYEAIPKNNSFTIMLSPQGRKFNQKLARELSQKEHLIFICGHYEGIDERVRQLIVDEEISIGDYILTGGEIAAMVIIDAVARLVPGVLGDEVSAEEESFSDQLLEYPHYTRPRNFRGLEVPEVLLSGNHKKIDLWRKKQSLLNTLFRRRDLLKVRGLTKEEKILLWQGFFELAMLIDEIPERSE
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATB_BORHD
Sequence: MEYRLLVGLEVHVQLGLKTKAFCGCKNDFGGIPNSRTCPTCLGLPGALPSVNKELINSAILAGHATNSKIRNIVKFDRKHYVYPDLPKGYQISQNDAPICNNGFIFIETSSGLKKINIVRIHMEEDSGKSLHLLESENRSYIDFNRAGAPLLEIVSEPDINSGEEAVAYLNSLREIFRYLDLSDCSMENGSFRCDVNVNLLINENDVEYKTPISEIKNLNSFKSIKLAIDYEESRQKEEWILHRKTFESIGKHTMGFDDKRGITVFQRSKETVADYRYIKDPDLPLIKLDDVYIESIKSNKMVELPLDTRIRLKEQYGLSNFDVVTLTSDKNLVKYFEEAAMTSSDPKRVSNWILSEVLSVLNDREISILDFNLPPSYISELVEFIVSGKVSGKIAKEIFLEMLKRNVSPAIIINEKNLEQISDKSFIESVVLEVLNENPKSIELYKKGKSHAIKFMMGQIMLKTSGRVNPAFANEILMNKLRDV
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: SYC_BURM9
Sequence: MESLRIYNTLARDKQDFVPRQPGEVRMYVCGITVYDYCHIGHARMVVVFDIVQRWLRARGYRVTYVRNITDIDDKIIRRAVENGETIQSLTRRFTDAMNADFDALGVERPDLEPRATEFIPQMLGMIEKLEANGYAYQAKDGDVNYSVRKFANYGRLSGKSLEDLRAGERVAANDAKEDPLDFVLWKRAKPQEPAGASWESKYGAGRPGWHIECSAMGCTLLGAHFDIHGGGQDLQFPHHENEIAQSEGATGQTFVNYWMHNGFVQVDSEKMSKSLGNFFTIREVLEKFDAEVVRFFIVRTHYRSPLNYSDVHLDDARASLTRLYTALKDATPDAQPLDWSEAHAQRFAAAMNDDFNTAVAVAVLFELATEVNRTREPALARQLRLLAGLLGLLGREPREFLQHAAGAARTGALEPHEIEARIAARVAAKQAKNYAEADRIRAELLEAGIALEDKPGGSTEWRRV
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_BACAH
Sequence: MNKEERAKRQSKIRNFSIIAHIDHGKSTLADRILEKTNALTQREMKAQLLDSMDLERERGITIKLNAVQLNYKAKDGEEYILHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNNLEILPVINKIDLPSADPERVRQEVEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDSEEPLQCMIFDSLYDPYRGVIAYIRVVNGTVKVGDKVRMMATGKEFEVTEVGVFTPKTTQRDELTVGDVGFLAASIKNVGDTRVGDTITHAKRPAAEPLAGYRKLNPMVFCGLYPIDSARYNDLRDALEKLELNDSALEFEPETSQALGFGFRCGFLGLLHMEIIQERIEREFKIDLITTAPSVIYKVFLTNGEDMIVDNPSNMPDPQIIDRVEEPFVKAAIMVPNDYVGAVMEICQGKRGTFIDMQYLDETRVTLTYEIPLSEIVYDFFDQLKSNTKGYASFDYELIGYKPSKLVKMDILLNSEQVDALSFIVHRDSAYDRGKVIVEKLKELIPRQQFEVPIQATIGNKVVARSTIKAMRKNVLAKCYGGDISRKRKLLDKQKEGKKRMKSVGSVEVPQEAFMAVLKMDDN
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SOX4_HUMAN
Sequence: MVQQTNNAENTEALLAGESSDSGAGLELGIASSPTPGSTASTGGKADDPSWCKTPSGHIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERLRLKHMADYPDYKYRPRKKVKSGNANSSSSAAASSKPGEKGDKVGGSGGGGHGGGGGGGSSNAGGGGGGASGGGANSKPAQKKSCGSKVAGGAGGGVSKPHAKLILAGGGGGGKAAAAAAASFAAEQAGAAALLPLGAAADHHSLYKARTPSASASASSAASASAALAAPGKHLAEKKVKRVYLFGGLGTSSSPVGGVGAGADPSDPLGLYEEEGAGCSPDAPSLSGRSSAASSPAAGRSPADHRGYASLRAASPAPSSAPSHASSSASSHSSSSSSSGSSSSDDEFEDDLLDLNPSSNFESMSLGSFSSSSALDRDLDFNFEPGSGSHFEFPDYCTPEVSEMISGDWLESSISNLVFTY
What is the function of this protein?
Transcriptional activator that binds with high affinity to the T-cell enhancer motif 5'-AACAAAG-3' motif (PubMed:30661772).  Required for IL17A-producing Vgamma2-positive gamma-delta T-cell maturation and development, via binding to regulator loci of RORC to modulate expression (By similarity).  Involved in skeletal myoblast differentiation by promoting gene expression of CALD1 (PubMed:26291311).
What are the official names of this protein?
Transcription factor SOX-4.
What are the subcellular locations of this protein?
Nucleus.
Protein: FDL46_ARATH
Sequence: MDDICCKDIISDLPEALICHLLSFVPTKEAALTSLLSEKWRYLFAFAPILDFDDSVWMQSPLVYMNEVHRKFMDFVDRVLGLQGNSTLVRFSLNCRNGIDRECIFRWISNVIERGVSDLDLGGNFVSNRSMPSSVFVSKSLVKLRIRTENCTIIDLEDVFLPKLKTLDLSSIWFRDGDTCLLKLISGCQVLEDLTMSDLWWDGYWNRSMSSKTLKRLTVHCSDWDRSPGSISFDTPNLVYFEYFDLVADKYEVVNFDSLVEASIGLRMRHHQRAHASYGDLVVNATNLFMGISNVRILQLFSNALEVLTFCCAPIPVFKKLIHLTVETDKDVGWESLPALLKNCPNLETLVFKGLHHRSTSKCQDTDGCLCKSSKDIRSCLSSSPVKVLKILKFGEVASYFGDEEKQLELVKYFLETMPNLEQMILHYNTRISEGVKSQLDWLVPRVSSSKCSVQLICDNAPTYPFYGGIICDNFITPAPTYPFFGDPLHGMVIPYMGDQPHFI
What are the official names of this protein?
Putative F-box/FBD/LRR-repeat protein At3g59240.
Protein: PUP_MYCLB
Sequence: MAQEQTRRGGGGDDDEFTSSTSVGQERREKLTEETDDLLDEIDDVLEENAEDFVRAYVQKGGQ
What is the function of this protein?
Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation.  The tagging system is termed pupylation.
What are the official names of this protein?
Prokaryotic ubiquitin-like protein Pup, Bacterial ubiquitin-like modifier.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic ubiquitin-like protein family.