PharMolix/UniProtQA huggingface dataset:
Protein: KTHY_CHLTE
Sequence: MLISFEGIDGAGKSTQVMKLKRYLQERGREVLALREPGGTPVAEEIRELLLERRNDITPVGELLLFAASRAELVQQVIQPALENDSDVILDRFFDSTTAYQGYGRGLDLDMLAEINRIASCRLVPDVTFYLDLTPEDALMRKFSEKSLPLAFESEELDRMENSGLDFYRRVREGYHKIGGENPNRIIIIDALLSPSEIHRKIISSIDALCTKTA
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: Y1947_MYCTU
Sequence: MTTPEYGSLRSDDDHWDIVSNVGYTALLVAGWRALHTTGPKPLVQDEYAKHFITASADPYLEGLLANPRTSEDGTAFPRLYGVQTRFFDDFFNCADEAGIRQAVIVAAGLDCRAYRLDWQPGTTVFEIDVPKVLEFKARVLSERGAVPKAHRVAVPADLRTDWPTPLTAAGFDPQRPSAWSVEGLLPYLTGDAQYALFARIDELCAPGSRVALGALGSRLDHEQLAALETAHPGVNMSGDVNFSALTYDDKTDPVEWLVEHGWAVDPVRSTLELQVGYGLTPPDVDVKIDSFMRSQYITAVRA
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase Rv1896c.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: SASA_SYNS3
Sequence: MDGIDRNPRQKLSLLLVAGRHHLSSRDLRELVEFLQNEDCGFDVSLQISDPTQQPELLELHRLVVTPSLVKLQPQPKQVFAGSSIFQQLRGWLPRWQQDEVVSGLGLSLKPTELDGSRTQRELQLEDQLLVLRQENETLIDRLQAQERLLRMVAHELRTPLTAATLAVQSQELGQIDIHRFRDVLKRRLEEIALLSKDLLEVGSTRWEALFNPQRLDLTSVAAEAILELEKLWLGRDVTIHTDIPADLPKVFADQRRMRQVLLNLLENALKYTPNGGLISLTMLHRTSQWVQVSISDSGPGIPEEEQQRIFLDRVRLPQTSAGASGFGVGLSVCRRIVEVHGGRIWVISEPEKGACFTFNVPIWQGQGQEKENVVLTEGQAEP
What is the function of this protein?
Member of the two-component regulatory system SasA/RpaA involved in genome-wide circadian gene expression.  One of several clock output pathways.  Participates in the Kai clock protein complex, the main circadian regulator in cyanobacteria, via its interaction with KaiC.  KaiC enhances the autophosphorylation activity of SasA, which then transfers its phosphate group to RpaA to activate it.  In addition to its output function, recruits fold-shifted KaiB (KaiB(fs)) to KaiC to cooperatively form the KaiB(6):KaiC(6) complex (independent of SasA kinase activity).  Required for robustness of the circadian rhythm of gene expression and is involved in clock output, also required for adaptation to light/dark cycles.
What are the official names of this protein?
Adaptive-response sensory kinase SasA, Sensor histidine kinase SasA.
Protein: VATB_SULIY
Sequence: MLSVREFSNISMIKGPLIYVQGVTDASYNELVEIEMPNGEKRRGLVIDSQMGIAIVQVFEGTTGVSPTGTKIRMLGRGLEVKISEEMLGRIFNPLGDSLDNGPPVIKGEKRDINGSPLNPAAREYPEEFIQTGISAIDGLNALLRGQKLPIFSGSGLPANMLAAQIAKQATVRGEESNFAVVFAAIGARYDDALFFRKFFEETGAINRVAMIVSLANEPPVMKTLTPKTALTLAEYLAFEQDMHVLAILIDMTNYCEALREISAAREEVPGRGGYPGYMYTDLATIYERAGKVLGKKGSITQMPILTMPNDDITHPIPDLTGYITEGQIVLDRALYNKGIYPPINVLMSLSRLAKDGIGEGKTRDDHKDVSNQLFASYARAVDTRGLAAIIGEDSLSEVDRKYLLFGELFERKFVSQGFNENRDIETTLDIGWEILSVLPESELTNIKTQYIKKYHPNYRGKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The archaeal beta chain is a regulatory subunit.
What are the official names of this protein?
V-type ATP synthase beta chain, V-ATPase subunit B.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: ASSY_SHIFL
Sequence: MTTILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEEDYDAIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNTTPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDTDFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEYLNSSVKIVNPIMGVKFWDESVKIPAEEVTVRFEQGHPVALNGKTFSDDVEMMLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHAHGRQLGRLLYQGRWFDSQALMLRDSLQRWVASQITGEVTLELRRGNDYSILNTVSENLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFGYAKTGLLSSSATSGLPQVENMENKGQ
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DBP3_CRYNJ
Sequence: MSAEELVASPKLSKEEKKARKEAKKLKKAEKAAKEAAAQEGVATEEVKEEVRKKDKKDKKEKKDKKRKEVDQEEAESPSTSTAATEEPPKKKKKSKDADSSETPVSTATPTESETPALSKKQQKKLAKASAAAAATSSAAAIPAPTVPTTFTAEHNTFLTSNNITLTPSLFPPLLSIRDLPINSKLQPFLNKFEKPTPIQACSWPALLSKKDVVGIAETGSGKTLAFGVPGINLLSQLPPVTGSKKGRGQVPGQIQMLVLAPTRELAQQSHEHLSAFGEQVGLKSVCIFGGVGKDGQARELSQKDTRVVVGTPGRTLDLADSGELDLSSVSYLVLDEADRMLDAGFENDIRRIIAHTPGHKEGRQTVMFSATWPESVRRLASTFLNNPLRITVGSDELSANKRIEQIVEVLDNPRDKDFRLTHHLKAHLKVHPNSKTSPTRILVFALYKKEAQRLEYTIRRAGYAVGALHGDMTQEARFKALEAFKTGQQNVLVATDVAARGLDIPDVGLVINVTFPLTTEDFVHRCGRTGRAGKTGKAVTFFTGENHEKSLAGEFMRVLRDVGAEIPKEMDRFPTTIKKKEHGSYGAFYKETTNAPAPTKITFD
What is the function of this protein?
ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis.  Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5. 8S rRNAs (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase DBP3.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ATBP_DROPS
Sequence: MGFPRILSKNNKIYTKLGEFCLSGDSFWIVCHTCQEELQTQDQFWKHIQDEHNFLHGVAKEHSRTSSYCLTDVEAAAATSGATTSQGAGSVTSVTVPLALYHCSTKYSEDDQREMDIHEAQQQQHQQQQQHQQQQQLQQQQQRDVAKELAELHANAVAVASAAAAAANESSTRSSSGIDIKIEPPCLTLPPEMQAAAAASNATIYHLPQLGPAAVPPPPPTTGFVSANVSTSTTVSTTPPNVTGSHSVMQQQAGVLTGSGLSTLSMSVGPSTAMAAALLSTQELPKDSNSTTASAGSAVSSDDGERWYICDYETCGLKFKYKSRMELHRVVHSKERRFNCELCSASFKQSCNLSTHRKKKHALRGIKSEILPQRF
What is the function of this protein?
May be a transcription factor for genes having (A+T) stretches in their promoter and/or enhancer regions.  Binds to AT rich DNA (By similarity).
What are the official names of this protein?
AT-rich binding protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: K2CA_BOVIN
Sequence: DAEQHGEVALKDANAKLQDLKAALQQAKEDLARLLKEYQELMNVKLALDIEIATYRTLLEGEECRMSGECQSSVSIEMVHNTTSSSSGGSGALGGGAGGRGGLGSGGLGSGSLGSGRLGSGGRGSRASRGNLALDSSSGGGSAVRGSVSNSGGSCAVSGVGGRGSVRVTQSSSQSQRSHHKL
What are the official names of this protein?
Keratin, type II cytoskeletal 68 kDa, component IA.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: DPS_SERP5
Sequence: MSTAKLVKTKSSELLYTRNDMDEKTKLDAIKALNRQVIQFIDLSLITKQAHWNMRGANFIAVHEMLDGFRTAIIDHQDTFAERIVQLGGVALGTVQVVNDKTPLKSYPTNIHSVQEHLKALADRYGAVANDIRKAITEVADEDTADMFTAASRDLDKFLWFIESNIE
What is the function of this protein?
During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages.  It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction.  One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.
What are the official names of this protein?
DNA protection during starvation protein.
What is the protein family that this protein belongs to?
Belongs to the Dps family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SET1B_CHICK
Sequence: MSFREIKAGEKAKHPEDHGKKQSSSWINGMENSTQASTSVEKRNHHWRSYKLIIDPALKKGQHKLYRYDGQHFSMPNSGIAPVDCVRDPRIGRIWTKTKELELSVPKFKIDEFYVGPVPPKQVTFAKLNDNIRENFLTDMCKKYGEVEEVEILYNPKNKKHLGIAKVIFATVKGAREAVQHLHNTSVMGNIIHVELDTKGETRMRFYELLVNGLYTPQTLPVGTEQDASPTVNETLQLTDSLKRLKDSNLSSVGSSVTPNSSTPFSHDTAYSSCRQDTPNSFSQFTPQSQGTPHTPRLGTPFSQDSTYSSRQTTPVYHFGQDSGYKHRRHETKFTDAYNRRPGGHHYVHNSPGVFRGTEHQFSTFKSHQQEPVQFSHTPPLSHSSSSSYKSAFSPYQAPAVFPQSEEQPFAQTSREAEYRRPAPPPAEMVVESSAATSADFAPVKEKPEEPPPLPDSNSAPEPSAPSFSQTPERSETPGTPTMESEMQHNSLDSRIEMLLKEQRTKLPFLNEHDSDNEVRMEGSPISSSSSQLSPIPMYGSNSQPGYRAQTPSSRPSSTGLEDISPTPLPDSDDDEPIPGTASLNQNSRGTSEASMTPIDQLNRASKVETLEVKEMVPGDQTPTSEKMDESQHSSGEDMEISDDEMNSAPITSAECAKTIVVNSSVSNAAVMAPSIPPLPPPPGFPPLPPPPPPPPQPAFPMPPPLPPPPPPTHPAVTVPPPPLPAPPGVPPPHILPPLPPFHPGMFPVMQVDMISVLGNHWGGMPMSFQMQTQMLSRMMQAQNTYQYPPFMGGRMQFVNLPPYRPFSMGAARGRGQQWPPLPKFDPSVPPPGYEPKKEDPHKATVDGVLLVIVKELKAIMKRDLNRKMVEVVAFRAFDDWWDKKERLAKASLTPVKSGGELEEKPKPKDRITSCLLENWNKGEGLGYEGIGLGIGLRGAIRLPSFKVKRKEPPEAASAGDQKRIRPSTSVDDEDEESERDRDASDTTSDLSKKDAEAVGLRRRPARPLELDSEGEEGDETSGKEEESSSEKEEEQEEEGGLVKAAPGKEEEEDEDDEEDEDDDEDEEDEEDYEETGVETSDKEEEQDSEEEDAASPSSSKAEVESSDESEDSSEFESSSDSDEDDDEEEEEEEDEEEEEEEEVAEDQDREAMVAETEHEPASHELPDDKRETILELYPVDYMDATGLGLSEPALVEKDEGMEEVKAEESECDQVPEESIAAETLKQLVMERDQETKLALSPICRPVEEPEPIVMLEPEVQECPKPESQDEAGTVCLSTPVAVFGEARPSKSSFFSKSDDSCLETHVKTKLPSAVEEEDRLPRTPGREVVVHSETDILLLPAHKVPSSTVPLPSTPGKEESVVPPEKFPEQLMVTKTSIEEEIPRTPGRDILAKSSHPLGKSQSTDTVPATPGSDAPLTGSSLTLSSPQVPGSPFSYPSQSPGINSGIPRTPGRDFNFTPTFPEAGATIPCLLSGKKQSEDDLDEKPFKEPLGASLTISMNSVPSPIPFASPTQADFRTDMGLPPNEPIPIAALPCIPGDGRMPIEECKAEVKSVLLSPEAPVGASILPPPPPHSVLPKRRPGRPRRSPPSVLSLDMYSGKTIEPPPVPVALVESAMSKELLSAHPDAFYGLKDPEAVTLDFRNDSFHEKIAAETVAEKLPFKELENQWNEDFKEEEAHAKPKRQWRRQKKSPEHLPVIPSPEYSPPQPQFRPRSEFEEMTILYDIWNGGIDEEDIKFMCITYDRLLQQDNGMDWLNDTLWVFHPSTSFSTPKKKKRDDGMREHVTGCARSEGYYKIDKKDKLKYLNNSRAFAEEPPADTQGMSIPAQPHASTRAGSERRSEQRRLLSSFTGSCDSDLLKFNQLKFRKKKLKFCKSHIHDWGLFAMEPIAADEMVIEYVGQNIRQVIADMREKRYEDEGIGSSYMFRVDHDTIIDATKCGNFARFINHSCNPNCYAKVITVESQKKIVIYSKQHINVNEEITYDYKFPIEDVKIPCLCGSENCRGTLN
What is the function of this protein?
Histone methyltransferase that specifically methylates 'Lys-4' of histone H3, when part of the SET1 histone methyltransferase (HMT) complex, but not if the neighboring 'Lys-9' residue is already methylated.  H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation.
What are the official names of this protein?
Histone-lysine N-methyltransferase SETD1B, SET domain-containing protein 1B.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily.
What are the subcellular locations of this protein?
Nucleus speckle. Chromosome.
Protein: EX7S_AGRVS
Sequence: MTDVAATDIAAYSFEKAVAELESIVARLERGDVALDESISIYERGELLKKHCEALLSAAENRIEKIRLDRAGKPVGAEPLDKD
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS21_LISMO
Sequence: MSKTVVRKNESLEDALRRFKRTVSKSGTLQESRKREFYEKPSVKRKKKSEAARKRKF
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: PXPA_BACC7
Sequence: MTTIDLNCDLGESFGAYKMGNDDEILPFVSSINVACGFHAGDPSVMRQTVEKAMQHNVAIGAHPGFPDLIGFGRRNMNVPASEVYDYVLYQIGALDGFVKAAGGKMHHVKPHGALYNMAATNPEIADAIAKAIYHINPSLLLYGLANSEAFIQAAEKYNITLIQEAFADRTYKQDGTLTSRTEENALIKNEEEAIKQVLQMVKEGYVNSVNGEKVAVQAQTICLHGDGEKAVQFAKRIYRTFEHNGISICAPK
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: TRPA_BACC0
Sequence: MGVERIKAAFENGKKAFIPYVMGGDGGLEILKERMRFLDEAGASIVEIGIPFSDPVADGPTIQRAGKRALDSGVTVKGIFQALIEVRKEVQIPFVLMTYLNPVLAFGKERFIERCLEAGVDGIIVPDLPYEEQDIIAPLLREANIALIPLVTVTSPIERIKKITSESEGFVYAVTVAGVTGVRQNFKDEIHSYLEKVKSHTHLPVVAGFGISTKEHVEEMVTICDGVVVGSKVIELLENEKREEICEFIQATKQKEEA
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: CHLN_STIHE
Sequence: MSQLITSPKINEKETLKFECETGNYHTFCPISCVSWLYQKIEDSFFLVIGTKTCGYFLQNALGVMIFAEPRYAMAELEEADISAQLNDYKELKRLCLQIKRDRNPSVIVWIGTCTTEIIKMDLEGMAPRLETEIGIPIVVARANGLDYAFTQGEDTVLAAMACRCPDKISTTSDSKNLETPMMIDNTQKNGQNSKALAHPPLVLFGSLPSAVVNVLTLELNKQGITVDGWLPSSRYTDLPALGEDVYVCGVNPFLSRTAMTLMRRKKCKLINAPFPIGPDGTRAWIEKICNVLGVIPTGLEEREKKIWQSLENYLPLVRGKSVFFMGDNLLEISLARFLTRCGMIVYECGVPYLDKRYQASELLLLEQTCLEKNVPMPRIVEKPDNYYQIQRIRELQPDLVITGMALSNPLEARGINTKWSVEFTFAQIHGFANSKDVLELVTRPLRRNMMQQVSNKTLVKPAK
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (ChlN-ChlB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit N, DPOR subunit N, LI-POR subunit N.
What is the protein family that this protein belongs to?
Belongs to the BchN/ChlN family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL30_RICAE
Sequence: MNNKINNIKITQVHSAIGRKYDQRLILVGLGLNKINKSVILANTNSIKGMVNKVKHLLKIENM
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: SYK_HAEIE
Sequence: MSEQEVKELDLNGEMLVRREKLSALRAKGNAFPNKFRRDALAQDLHNQYDSEDGEILKEKGVEVQVAGRIMTRRAMGKATFITIQDMSGKIQLYVARDNLPEGVYAEDVGNWDLGDIIGVKGTLFKTKTNELTIKTTEVQLLTKALRPLPDKFHGLTDQEVRYRQRYLDLISNEESRRTFIIRSKVVAGIREYFISKGFMEVETPMLQVIPGGASARPFVTHHNALDVDMYLRIAPELYLKRLVVGGFERVFELNRNFRNEGVSVRHNPEFTMLEYYQAYADYHDLMDNTEELLRKLAIDILGTTIVKYGDLEFDFGKPFERITLHDATVKYGADKGIVKEDLYDFDRAKATAERLGIEVQKSWGLGSIVNAIFEEVAEHHLIQPTFLMAHPAEISPLARRNDENPEVTDRFELFIGGREIGNGFSELNDAEDQNERFDAQVAAKEAGDDEAMFKDEDFVVALEHGLPPTAGEGLGIDRLAMLYANAPSIRDVILFPAMRQK
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NECA3_MOUSE
Sequence: MACAGLLTVCLLGPPAPQQPRHSAPAAGHALFQDVFRRADKNDDGKLSFEEFQNYFADGVLSSAELRELFSGIDDHLTDNLETEKLCDYFSTHLGVYRPVLAALESLNRAVLTAMDTTKLEYEQASKVDQFVTRFLLRETVNQLQALQTSLEGASDTLEAQAHGQRLDEETIKAQSRPCGSRRAGRRALRSISWSPSWSPGSSDTGRSSEAEQQWRLQVNRLQELIDQLECKAPRLEPTHEEDLTKGFDSHILVAQRQVQVAEDALQDFHRALCCYMNFTGAQSHCLHVSAQKMLDNAAFTLYEFWQDEASWRRHQQSPCSKAFQRTLIDHLQAPDTLTTVFFPASWWIMNNN
What is the function of this protein?
Inhibits the interaction of APBA2 with amyloid-beta precursor protein (APP), and hence allows formation of amyloid-beta (By similarity).  May enhance the activity of HIF1A and thus promote glycolysis under normoxic conditions; the function requires its ABM domain and may implicate the stabilization of the interaction between HIF1AN and APBA3 (By similarity).
What are the official names of this protein?
N-terminal EF-hand calcium-binding protein 3, Amyloid-beta A4 protein-binding family A member 2-binding protein, X11L-binding protein 51, mXB51.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: RNH_PSEA8
Sequence: MTDKEQVVIYTDGACKGNPGRGGWGALLLYKGAERELWGGEPDTTNNRMELMAAIQALAALKRSCPIRLITDSEYVMRGITEWLPNWKKRGWKTASKQPVKNADLWQALDEQVARHQVEWQWVRGHTGDPGNERADQLANRGVAELPR
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_CANAL
Sequence: MSAPINKEKVEQEAEQQIHKIRITLTSTKVKQLENVSANIIRNAAQYNIVKKGPVRMPTKVLKITTRKTPNGEGSKTWDAYEMRIHKRVIDLQAPASTVKRITQITIEPGVDVEVTIAA
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
40S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: VATA_STRPQ
Sequence: MNQGKIITVSGPLVVASGMQEANIQDICRVGHLGLVGEIIEMRRDQASIQVYEETSGIGPGEPVVTTGCPLSVELGPGLISEMFDGIQRPLDRFQKATDSDFLIRGVAIPSLDRKAKWAFIPKLSVGQEVVAGDILGTVQETAVIEHRIMVPYKVSGTLVAIHAGDFTVTDTVYEIKQEDGSIYQGSLMQTWPVRQSRPVAQKLIPVEPLVTGQRVIDTFFPVTKGGAAAVPGPFGAGKTVVQHQIAKFANVDIVIYVGCGERGNEMTDVLNEFPELIDPNTGQSIMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYSVAIMADSTSRWAEALREMSGRLQEMPGDEGYPAYLGSRIAEYYERAGRVRTLGSQEREGTITAIGAVSPPGGDISEPVTQNTLRIIKVFWGLDAPLAQRRHFPAINWLTSYSLYQDDVGSYIDRKQESNWSNKVTRAMAILQREASLEEIVRLVGLDSLSEQDRLTMAVARQIREDYLQQNAFDSVDTFTSFPKQEAMLTNILTFNEEASKALSLGAYFNEIMEGTAQVRDRIARSKFIPEENLEQIKGLTQKVTKEIHHVLAKGGI
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type alpha chain is a catalytic subunit.
What are the official names of this protein?
V-type ATP synthase alpha chain, V-ATPase subunit A.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: SED4_CANGA
Sequence: MVFDSEYDLGYPVYGAQFLSDGMLLVAGGGGVGVMIPNKLTALRVNFEKKKVLKRYREITLDSQDDSPSNLGVAQNMILMGCNEGYDKISSTGENHHIRKFVFENDHLKFIGAIDFDGSTDPEVYTKLICMSKDGTIAAIASSKLPTVIRIIDPIDLTEKYEIETGRDVRDIHFSPDGKLLVYITATSLEVVSVVTGRFLFRKTDFNKATDLARVKFINDDDFVLASGFKDKAGIALTTFRIRNTNPTILSSKKVFKDYKKITAMDVDPKGQLIALTTDDNSLALLSVKKLNVIKLFKQVHKDTITRVTVSPGGQYVATGSTDKTVHIFKISPDAMGGSNLWKSLLRFLFNVMKLAVVVIWAHLFYKYDLHHKLYDVTKVQLEKRSIEFPSFLDGILGTTTTRSTIIEGDIVSVVTDTAPALTSSVFSEDNKEYAKVEETTPSNSWSSVSESYWPSEVSNDIESVQENFDDIENKILENEDVVMKNDAIETEDESVGFDIDDTIKPIAPIDIDLELDDPLASTSVDTSEVLSSQVPVQLETLSGQSEIIDDKPEHLDEEVSEGFLGDHSKANLETEIENASTSISIEESTNSHSTFIESSSSLEEGRNTTSESSREISSETSIIKEDMLYPTENVSEQSATDKVNKNQSIDKIDVSSSSSIPTSSEGSSNSIVGDEAQMHISSLSSIETELSSSSIMINEESTIRNADSVVDENHSESKLPTEAKTSIVGSIDNENIDSTELNNLEEAVKTSSNESSLSQVTEELVKNNERVSNQSLSTVSTEHTEMKESSNLTEKKPESNSPESNLSESSLQTHDFSQISDTERNIVSSSAFVTDLPSEEASVNPGNTEGTIVNASLVDSQSSNSSVKTVETNVSQDEQTSQNETLSVGAATIDVIQGSYTSVSDSLDGMNNEEVGNKVHIEDVSNTLEIDSSASALSEQGDNQFSDSTPEVVNVINEFTTTPENETSSPLASSSTTFMTESPSPIAVANEVIENIQQDEQVAQQMEDTNSGSSNFQDTQHNVINDEL
What is the function of this protein?
Putative guanine nucleotide-exchange factor (GEF) involved in the formation or budding of transport vesicles from the ER.  Positive regulator of SAR1 probably through inhibition of the GTPase activation by SEC23 (By similarity).
What are the official names of this protein?
Putative guanine nucleotide-exchange factor SED4.
What is the protein family that this protein belongs to?
Belongs to the WD repeat SEC12 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein. Note=In the process of transport, SED4 itself may migrate to the Golgi apparatus and function in subsequent transport events.
Protein: G137B_HUMAN
Sequence: MRPERPRPRGSAPGPMETPPWDPARNDSLPPTLTPAVPPYVKLGLTVVYTVFYALLFVFIYVQLWLVLRYRHKRLSYQSVFLFLCLFWASLRTVLFSFYFKDFVAANSLSPFVFWLLYCFPVCLQFFTLTLMNLYFTQVIFKAKSKYSPELLKYRLPLYLASLFISLVFLLVNLTCAVLVKTGNWERKVIVSVRVAINDTLFVLCAVSLSICLYKISKMSLANIYLESKGSSVCQVTAIGVTVILLYTSRACYNLFILSFSQNKSVHSFDYDWYNVSDQADLKNQLGDAGYVLFGVVLFVWELLPTTLVVYFFRVRNPTKDLTNPGMVPSHGFSPRSYFFDNPRRYDSDDDLAWNIAPQGLQGGFAPDYYDWGQQTNSFLAQAGTLQDSTLDPDKPSLG
What is the function of this protein?
Acts also as a negative regulator of osteoclast activity (By similarity).  Involved in interleukin-4-induced M2 macrophage polarization (By similarity).
What are the official names of this protein?
Integral membrane protein GPR137B, Transmembrane 7 superfamily member 1 protein.
What is the protein family that this protein belongs to?
Belongs to the GPR137 family.
Protein: LPXK_BACFN
Sequence: MEENSIKIHKWLYPASWLYGAGVALRNKLFDWGKLQSKSFNVPIICIGNIAVGGTGKTPHTEYLIKLLHDEFQVAVLSRGYKRHTKGFILSTAESDARSIGDEPYQIQSKFSDIRVAVDEDRCHGIERLLTLKEPPVEVILLDDAFQHRYVKAGLNILLTDYHRLFCDDTLMPAGRLREPAQGKNRAQIVIVTKCPPDIKPIDYNIITKRLNLFPYQQLYFSSFRYGNLRAVFPDCATVQERKLSSLQTEEQILLITGIASPDTIIRELEIHTRNIDLLAFSDHHNFSQRDLAQIKERFGKLRKGQRLIVTTEKDATRLICHQELDEGLKPFIYALPIEVEILQNQQDNFNQHIIGYVRENTRNGSLPERKDAHKS
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: Y3225_PROMH
Sequence: MNRIVEKWMYRSRWLFAPVYIGLSLGLLALTIKFFQSMYEILPNIFALSEADLVLRLLSLIDLALVGGLLIMVIFSGYENFITNMEIEGAKDKLSWLGNMDAESLKNKVAASIVAISSIHLLGVFMDLKNIPDNKLLWYVVLHLTFVFSAFVMGYLEKISKRSKRANKANQG
What are the official names of this protein?
UPF0114 protein PMI3225.
What is the protein family that this protein belongs to?
Belongs to the UPF0114 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL3_LISMO
Sequence: MTKGILGRKVGMTQVFTENGELIPVTVIEAAQNVVLQKKTVETDGYEAVQIGFEDKRAILSNKPEQGHVAKANTTPKRFIREFRDVNLDEYEIGAEVKVDVFAEGDIIDATGVSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKLLPGRMGGEQITIQNLEIVKVDVEKNVLLVKGNVPGAKKALVQIKTATKAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.