PharMolix/UniProtQA huggingface dataset:
Protein: ATP6_CAMJD
Sequence: MKDLFLFSSLLDASHTFSYFFHIGLVALIAVIVAMMATRSMQLVPRGMQNLAEAFLEGVLSMGRDTMGSEKGVRKYLPLVATLGIIVFFSNIIGILPGFHAPTASLNLTLSLAIIVFVYYHFEGIRAQGFIKYFAHFMGPIKLLAPLMFPIEIVSHLSRVVSLSFRLFGNIKGDDLFLMVILALVPYIAPLPAYVLLTFMAFLQAFIFMILTYVYLAGATVVEKGH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PGK_FRASN
Sequence: MRTIDDLQVTGHRVLVRSDLNVPLDHSKGAPRITDDGRVRASVPTIQALLDRNAKVIVCSHLGRPKGAPEEKYSLAPVAERLAELLGIPVAFAGDGGGDIAGDRAREVVGQLAEGQVALLENLRFHPGETSKDTVARATFADELSALAEFYVGDAFGAVHRAHASVSEVPKRLPHAAGRLVLTELEVLRALTAAPARPYAVVLGGSKVSDKLGVIRALLPKVDALLVGGGMCFTFLAALGHPVGASLLESEMIDTCKDLLAEAGDRLVLPTDVVVADRFAADAETAVVAADAIPDGWLGLDIGPASTAAFARVVAGAATIFWNGPMGVFEFAPFAEGTRGVAEAVASGGGFSVVGGGDSAAAVRILGIPEDDFSHISTGGGASLEYLEGKTLPGLAALDV
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCKA_HAEI8
Sequence: MTDLNKVVKELEALGIYDVKEVVYNPSYEQLFEEETKPGLEGFEKGTLTTTGAVAVDTGIFTGRSPKDKYIVLDEKTKDTVWWTSETAKNDNKPMNQATWQSLKDLVTNQLSRKRLFVVDGFCGASEHDRIAVRIVTEVAWQAHFVKNMFIRPTEEQLKNFEPDFVVMNGSKVTNPNWKEQGLNSENFVAFNLTERIQLIGGTWYGGEMKKGMFSMMNYFLPLKGVGAMHCSANVGKDGDVAIFFGLSGTGKTTLSTDPKRELIGDDEHGWDDVGIFNFEGGCYAKTIHLSEENEPDIYHAIRRDALLENVVVRSDGSVDFDDGSKTENTRVSYPIYHIDNIVKPVSRAGHATKVIFLTADAFGVLPPVSKLTPEQTKYYFLSGFTAKLAGTERGITEPTPTFSACFGAAFLTLHPTQYAEVLVKRMQAAGAEAYLVNTGWNGTGKRISIKDTRGIIDAILDGSIEKAEMGELPIFNLAIPKALPGVDSAILDPRDTYADKAQWQSKAEDLAGRFVKNFVKYATNEEGKALIAAGPKA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROQ_SHELP
Sequence: MSKAVKILLVNGPNLNLLGRREPGHYGHHTLAQIVEQLKLLAGEQGASLDHIQSNAEHELIDAIHQSDADFIIINPAAFTHTSVALRDALLGVAIPFIEVHLSNVHAREAFRHHSYFSDKAVGVICGLGEQGYRYALDSAIARVRAAQEK
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: AKTS1_MOUSE
Sequence: MASGRPEELWEAVVGAAERFQARTGTELVLLTAAPPPPPRPGPCAYAAHGRGALAEAARRCLHDIAQAHRAATATRPPGPPPAPQPPSPAPSPPPRPALAREDEEEDEDEPTETETSGERLGGSDNGGLFMMDEDATLQDLPPFCESDPESTDDGSLSEETPAGPTACPQPPATALPTQQYAKSLPVSVPVWAFKEKRTEARSSDEENGPPSSPDLDRIAASMRALVLREAEDTQVFGDLPRPRLNTSDFQKLKRKY
What is the function of this protein?
Subunit of mTORC1, which regulates cell growth and survival in response to nutrient and hormonal signals.  mTORC1 is activated in response to growth factors or amino acids.  Growth factor-stimulated mTORC1 activation involves a AKT1-mediated phosphorylation of TSC1-TSC2, which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1.  Amino acid-signaling to mTORC1 requires its relocalization to the lysosomes mediated by the Ragulator complex and the Rag GTPases.  Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis.  mTORC1 phosphorylates EIF4EBP1 and releases it from inhibiting the elongation initiation factor 4E (eiF4E).  mTORC1 phosphorylates and activates S6K1 at 'Thr-389', which then promotes protein synthesis by phosphorylating PDCD4 and targeting it for degradation.  Within mTORC1, AKT1S1 negatively regulates mTOR activity in a manner that is dependent on its phosphorylation state and binding to 14-3-3.  Inhibits RHEB-GTP-dependent mTORC1 activation.  Substrate for AKT1 phosphorylation, but can also be activated by AKT1-independent mechanisms.  May also play a role in nerve growth factor-mediated neuroprotection.
What are the official names of this protein?
Proline-rich AKT1 substrate 1, Proline-rich AKT substrate.
Protein: Y2711_STAAC
Sequence: MTNFTFDGAHSSLEFQIKHLMVSKVKGSFDQFDVAVEGDINDFSTLKATATIIPSSINTKNEARDNHLKSGDFFGTDEFDKITFVTKSVSESKVVGDLTIKGITNEETFDVEFNGVSKNPMDGSQVTGIIVTGTINREKYGINFNQALETGGVMLGKDVKFEASAEFSISE
What are the official names of this protein?
UPF0312 protein SACOL2711.
What is the protein family that this protein belongs to?
Belongs to the UPF0312 family.
Protein: RSXC_ECOSE
Sequence: MLKLFSAFRKNKIWDFNGGIHPPEMKTQSNGTPLRQVPLAQRFVIPLKQHIGAEGELCVSVGDKVLRGQPLTRGRGKMLPVHAPTSGTVTAIAPHSTAHPSALAELSVIIDADGEDCWIPRDGWADYRSRRREELIERIHQFGVAGLGGAGFPTGVKLQGGGDKIETLIINAAECEPYITADDRLMQDCAAQVVEGIRILAHILQPREILIGIEDNKPQAISMLRAVLADSHDISLRVIPTKYPSGGAKQLTYILTGKQVPHGGRSSDIGVLMQNVGTAYAVKRAVIDGEPITERVVTLTGEAIARPGNVWARLGTPVRHLLNDAGFCPSADQMVIMGGPLMGFTLPWLDVPVVKITNCLLAPSANELGEPQEEQSCIRCSACADACPADLLPQQLYWFSKGQQHDKATTHNIADCIECGACAWVCPSNIPLVQYFRQEKAEIAAIRQEEKRAAEAKARFEARQARLEREKAARLERHKSAAVQPAAKDKDAIAAALARVKEKQAQATQPIVIKAGERPDNSAIIAAREARKAQARAKQAELQQTNDAATVADPRKTAVEAAIARAKARKLEQQQANAEPEEQVDPRKAAVEAAIARAKARKLEQQQANAEPEEQVDPRKAAVEAAIARAKARKLEQQQSNAEPEEQVDPRKAAVEAAIARAKARKLEQQQANAEPEEQVDPRKAAVEAAIARAKARKLEQQQTNAEPEEQVDPRKAAVAAAIARAQAKKAAQQKVVNED
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit C, Rsx electron transport complex subunit C.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: AMYB_ASPAW
Sequence: MMVAWWSLFLYGLQVAAPALAATPADWRSQSIYFLLTDRFARTDGSTTATCNTADQKYCGGTWQGIIDKLDYIQGMGFTAIWITPVTAQLPQTTAYGDAYHGYWQQDIYSLNENYGTADDLKALSSALHERGMYLMVDVVANHMGYDGAGSSVDYSVFKPFSSQDYFHPFCFIQNYEDQTQVEDCWLGDNTVSLPDLDTTKDVVKNEWYDWVGSLVSNYSIDGLRIDTVKHVQKDFWPGYNKAAGVYCIGEVLDGDPAYTCPYQNVMDGVLNYPIYYPLLNAFKSTSGSMDDLYNMINTVKSDCPDSTLLGTFVENHDNPRFASYTNDIALAKNVAAFIILNDGIPIIYAGQEQHYAGGNDPANREATWLSGYPTDSELYKLIASRNAIRNYAISKDTGFVTYKNWPIYKDDTTIPMRKGTDGSQIVTILSNKGASGDSYTLSLSGAGYTAGQQLTEVIGCTTVTVGSDGNVPVPMAGGLPRVLYPTEKLAGSKICSSS
What are the official names of this protein?
Alpha-amylase B, 1,4-alpha-D-glucan glucanohydrolase B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: TUSE_SHIBS
Sequence: MLIFEGKEIETDTEGYLKESSQWSEPLAVVIAENEGISLSPEHWEVVRFVRDFYLEFNTSPAIRMLVKAMANKFGEEKGNSRYLYRLFPKGPAKQATKIAGLPKPVKCI
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.  Could accept sulfur from TusD (By similarity).
What are the official names of this protein?
Sulfurtransferase TusE, tRNA 2-thiouridine synthesizing protein E.
What is the protein family that this protein belongs to?
Belongs to the DsrC/TusE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCNT1_MOUSE
Sequence: MARAKLPRSPSEGKAGPGDTPAGAAAPEEPHGLSPLLPARGGGSVGSDVGQRVQVEFYVNENTFKERLKLFFIKNQRSSLRIRLFNFSLKLLTCLLYIVRVLLDNPDQGIGCWGCTKYNYTFNGSSSEFHWAPILWVERKMALWVIQVIVATISFLETMLIIYLSYKGNIWEQIFHVSFVLEMINTLPFIITVFWPPLRNLFIPVFLNCWLAKHALENMINDFHRAILRTQSAMFNQVLILFCTLLCLVFTGTCGIQHLERAGGNLNLLTSFYFCIVTFSTVGFGDVTPKIWPSQLLVVILICVTLVVLPLQFEELVYLWMERQKSGGNYSRHRARTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPSEMDVQVRRVLQIPLWSQRVIYLQGSALKDQDLMRAKMDNGEACFILSSRNEVDRTAADHQTILRAWAVKDFAPNCPLYVQILKPENKFHVKFADHVVCEEECKYAMLALNCICPATSTLITLLVHTSRGQEGQESPEQWQRTYGRCSGNEVYHIRMGDSKFFREYEGKSFTYAAFHAHKKYGVCLIGLKREENKSILLNPGPRHILAASDTCFYINITKEENSAFIFKQEEKQKRRGLAGQALYEGPSRLPVHSIIASMGTVAMDLQNTDCRPSQGGSGGDGTKLTLPTENGSGSRRPSIAPVLELADSSALLPCDLLSDQSEDEVTPSDDEGLSVVEYVKGYPPNSPYIGSSPTLCHLLPVKAPFCCLRLDKGCKHNSYEDAKAYGFKNKLIIVSAETAGNGLYNFIVPLRAYYRSRRELNPIVLLLDNKPDHHFLEAICCFPMVYYMEGSVDNLDSLLQCGIIYADNLVVVDKESTMSAEEDYMADAKTIVNVQTMFRLFPSLSITTELTHPSNMRFMQFRAKDSYSLALSKLEKQERENGSNLAFMFRLPFAAGRVFSISMLDTLLYQSFVKDYMITITRLLLGLDTTPGSGYLCAMKVTEDDLWIRTYGRLFQKLCSSSAEIPIGIYRTECHVFSEPHDVRAQSQISVNMEDCEDTREAKGPWGTRAASGSGSTHGRHGGSADPVEHPLLRRKSLQWARKLSRKSTKQAGKAPVATDWITQQRLSLYRRSERQELSELVKNRMKHLGLPTTGYEDVANLTASDVMNRVNLGYLQDEMNDHHQNTLSYVLINPPPDTRLEPNDIVYLIRSDPLAHVASSSQSRKSSCSNKLSSCNPETRDETQL
What is the function of this protein?
Outwardly rectifying potassium channel subunit that may coassemble with other Slo-type channel subunits.  Activated by high intracellular sodium or chloride levels.  Activated upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1.  May be regulated by calcium in the absence of sodium ions (in vitro) (By similarity).
What are the official names of this protein?
Potassium channel subfamily T member 1.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. KCa4.1/KCNT1 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RU1C_DROPS
Sequence: MPKYYCDYCDTYLTHDSPSVRKTHCTGRKHRDNVKFYYQKWMEEQAQHLIDATTAAFKAGKITNNPFAGGPSSAPPKPSGVSIPPPNMGAPPRPGMPGMPFMPPMMNPMMTGMRPPPIMNPMAMMGPPPPLGTIPGVRPPIMNGPK
What is the function of this protein?
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome.  U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing.  The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA.  Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
What are the official names of this protein?
U1 small nuclear ribonucleoprotein C, U1 snRNP C, U1-C, U1C.
What is the protein family that this protein belongs to?
Belongs to the U1 small nuclear ribonucleoprotein C family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DFRA_DIACA
Sequence: MVSSTINETLDGKHDINKVGQGETVCVTGASGFIGSWLIMRLLERGYTVRATVRDPDNTKKVQHLLDLPNAKTNLTLWKADLHEEGSFDAAVDGCTGVFHIATPMDFESKDPENEMIKPTINGMLDILKSCVKAKLRRVVFTSSGGTVNVEATQKPVYDETCWSALDFIRSVKMTGWMYFVSKILAEQAAWKYAAENNLEFISIIPPLVVGPFIMPSMPPSLITALSPITRTESHYTIIKQGQFVHLDDLCMSHIFLYENPKANGRYIASACAATIYDIAKMLREEYPEYNVPTKFKDYKEDMGQVQFSSKKLTDLGFEFKYGLKDMYTAAVESCRAKGLLPLSLEHHLCVFRVTLIFFK
What is the function of this protein?
Bifunctional enzyme involved in flavonoid metabolism.
What are the official names of this protein?
Dihydroflavonol 4-reductase, DFR, Dihydrokaempferol 4-reductase, Flavanone 4-reductase, FNR.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.
Protein: SYV_CORJK
Sequence: MPCLARLLDLADVSDSSSKANGSNPIGADRSAQLPAAWDPAAVEENLYQGWVDSGYFKADPSSDKPPFSIVLPPPNVTGQLHMGHALDHTLMDAMARRKRMQGFEVLWLPGSDHAGIATQTKVEANLKETEGKDRFDYGRDAFVGKVWEWKDRYGGVIQRQMRAIGDSVDWSRERFTLDDGLSRAVQTMFKELFDAGLIYRANRMVNWSPVLQTAISDIEVVYSDDEGELVSIRYGSLEDSEPHVVVATTRVETMLGDVAVAVHPEDERYTDLVGKSLPHPFLPDRQMIVVADDYVDPEFGTGAVKITPAHDPNDFAMGQRHDLPMPVIMDETGHIANTGTEFDGMERYEAREKIRLALEEQGRIVARKFPYVHSVGHSERSKEAVEPRLSEQWFVKVEELAKMSGDAIRSGDSVIHPSSQEPRWFDWVDDMHDWCISRQLWWGHRIPIWYGPNGEIVCCGPDDEAPTGEGWYQDEDVLDTWFSSALWPFSTMGWPEKTPELEKFYPTSVLVTGYDILFFWVARMMMFATFASKHTPEILGTGKDGRPQIPFNDIFLHGLVRDEHGRKMSKSLGNGIDPMDWVRDYGADALRFTLARGANPGSDLPVGEDAAQSSRNFATKLYNATKFALMNGARVGELPARETLTDADRWILDRLEEVRQLVDDALDRYEFSLANENLYRFAWGEFCDWYLEIAKVQIPRDWDSATEEQVQRGIRTQIVLGRVLDSVLRLLHPAMPFVTETLWKALTDGEEGYSESLVTADWPTADLTNGGAQTDADAVRRMADVDKLVTELRRFRSDQGVKPSQKVPAKLDFAAADLANFEEAVRSLVRLETPEEDFAETASIEVRLSQATIAVQLDTSGTVDVAAERKRLEKDLAAAQKELDNAAKKLGNENFLAKAPEKVVEGIRERQRVAQEEFERITARLEGLPKA
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUC_THIDA
Sequence: MAGQTLFQKLWDAHVVHVEPDGTTLLYIDRHLVHEVTSPQAFEGLKLAQRLPRRPDAAIAVPDHNVPTTDRSQGIADPVSRLQVETLDANCAEFGITEFRMDDVRQGIVHVIGPEEGLTLPGMTVVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQCLWQKPSKTMLVKVEGELGKGVTAKDIALAVIGRIGTAGGTGYAIEFGGAAIRALSMEGRMTLCNMAIEAGARAGMVAVDQTTIDYVEGRPYAPTGEAWDTAVAWWKTLHSDADAVFDRVVELDAAAIEPQVTWGTSPEMVTTVGASVPDPSAAPSEVKRQDWVRALEYMGLAAGTPVSAIALDKVFIGSCTNSRIEDLREAAAVAKGRRVAPNVKLAMVVPGSGLVKQQAEAEGLDRIFIDAGFEWREPGCSMCLAMNADRLEPGERCASTSNRNFEGRQGQGGRTHLVSPAMAAAAACAGHFVDVRNF
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: RUTB_ECOLU
Sequence: MTILTARPEAITFDPQQSALIVVDMQNAYATPGGYLDLAGFDVSTTRPVIANIQTAVTAARAAGMLIIWFQNGWDEQYVEAGGPGSPNFHKSNALKTMRKQPQLQGKLLAKGSWDYQLVDELVPQPGDIVLPKPRYSGFFNTPLDSILRSRGIRHLVFTGIATNVCVESTLRDGFFLEYFGVVLEDATHQAGPEFAQKAALFNIETFFGWVSDVETFCDALSPTSFARIA
What is the function of this protein?
Hydrolyzes ureidoacrylate to form aminoacrylate and carbamate.  The carbamate hydrolyzes spontaneously, thereby releasing one of the nitrogen atoms of the pyrimidine ring as ammonia and one of its carbon atoms as CO2.
What are the official names of this protein?
Ureidoacrylate amidohydrolase RutB.
What is the protein family that this protein belongs to?
Belongs to the isochorismatase family. RutB subfamily.
Protein: HIS1_NOCFA
Sequence: MLRVAVPNKGALSESATSILSEAGYRKRTDSRDLSVLDPENQVEFYFLRPKDIAVYVGSGELDLGITGRDLALDSGAPVQERLALGFGRSTFRYAAPAGREWKVEDLYDKRIATSYPNLVLSDLRRRGIEAEVIRLDGAVEISIQLGVADAIADVVGSGRTLRQHNLVAFGETLCDSEGVLVERVGADRDDRARNQLVARIQGVVFAQQYLMLDYDCPKELLDQAVQITPGLESPTVSPLADEGWVAVRALVPRGKGNSVMDRLADLGAKAILATDIRSCRAF
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLD7_YEASL
Sequence: MSRKLCTLNFTLSGKQGSLVIRDIQLWSNRPTASKSTSELRGQFIQYVDLAKLPLWVRSTNMNTYRCYSTSATAQAYFKSKLRNANRGIVIELSDKVDQRSQEPAYLIIFRENTELNCFQVDLTMKHEFDGQVTKLKQEIGKTRASVSKEGSIDIIIQQSQQRKIGTKTKVYRNVHINDKRLQFNETLSKLILGGLRLRGISNSITDYQKLYKITFDAAEFTHRDELKRISMGSXEEVSFESLQETVETLLKLFTKS
What is the function of this protein?
Required for the proper function of SLD3 at the initiation of DNA replication.  Binds to SLD3 and reduces its affinity for CDC45, a component of the replication fork.  Required for mitochondrial morphology (By similarity).
What are the official names of this protein?
Mitochondrial morphogenesis protein SLD7, Synthetic lethality with DPB11-24 mutation protein 7.
What is the protein family that this protein belongs to?
Belongs to the SLD7 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle pole.
Protein: RBFA_MOOTA
Sequence: MAVTARNQRVAEEMKKEIARIIRDEVKDPRLEAGLVSVTGVELSNDRHYAKVYVSIYGDEEARNQAMEGLARATSFIRREIGQRLSLRYTPEITFKLDVSIEHGDHINRLLARVRAGEYADE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACR5_ARATH
Sequence: MDVCLSYSYNMDDEIAKFIRRVNPPRVVIDNEVCKDVTVIKVDSANKHGILLEVVQVLTELNLTIKKAYISSDGGWFMDVFNVTDQDGNKVTDEIVLEYIRKSLGPDESSCFSPSMRSTIGVKQSVDYTVVELTGTDRPGLLSELCAVLMDLQCNVVNAEIWTHRAKAAAVLQVTDEETCSAITDPERLSKIRKLLGYVLTGGSSGRRFREPKTTVSSALNETHTDRKLHQLMFADRDYDEWENNVDDEDKCGRVIPDVDVSNLHDLDYSIVMIKCKDRPKLLFDTVFTLTDMNYVVSHASIDAEGPQAYQEYYIRHTDGSPVKSEAERQRVIKCLKAAIQRRVSEGLKLELCTSDRVGLLSDVTRIFRENSLTVTRAEVKTKGDKALNTFYVRDASGYQVDTKTIESIRQVIGQTILQVKGGNTDAKPSPQDSPTGFLFGVFKSRSFVNFGLIRS
What is the function of this protein?
May bind amino acids.
What are the official names of this protein?
ACT domain-containing protein ACR5, Protein ACT DOMAIN REPEATS 5.
Protein: YTFQ_ECOLI
Sequence: MWKRLLIVSAVSAAMSSMALAAPLTVGFSQVGSESGWRAAETNVAKSEAEKRGITLKIADGQQKQENQIKAVRSFVAQGVDAIFIAPVVATGWEPVLKEAKDAEIPVFLLDRSIDVKDKSLYMTTVTADNILEGKLIGDWLVKEVNGKPCNVVELQGTVGASVAIDRKKGFAEAIKNAPNIKIIRSQSGDFTRSKGKEVMESFIKAENNGKNICMVYAHNDDMVIGAIQAIKEAGLKPGKDILTGSIDGVPDIYKAMMDGEANASVELTPNMAGPAFDALEKYKKDGTMPEKLTLTKSTLYLPDTAKEELEKKKNMGY
What is the function of this protein?
Part of the ABC transporter complex YtfQRT-YjfF involved in galactofuranose transport (Probable).  Binds to both alpha- and beta-galactofuranose (PubMed:19744923).
What are the official names of this protein?
Galactofuranose-binding protein YtfQ.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 2 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RECF_CLOBM
Sequence: MYIKSVHLINFRNYDDMYLELSPNTNIFVGNNAQGKTNILESIYYSSIGKSHRTNKDKDLIKWDKNNTYLRTYVSRERLDKTIDINIFKNGKKAITVNKIKIKKISELMGNLNVVMFSPEDLRIIKDSPGNRRKFLDIELCKINNVYYHDLVQYNKILSERNTALKNWNNRINDIIDVYDEQLSKYGAFIIKERNKYLDKLNIIGKNIHKKITNDLEDINFRYLTNIKDFDNAEKELLMLFKKNRKKDLERNSTSIGPHRDDFEVSINNIDTRIFGSQGQQRTAVLTLKFASLEIIKNIIGEYPALLLDDVLSELDSNRQKFVLNSIDKIQTIITCTGIEEIDKYLDKKQSQLYLVNNGKIKKV
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YL115_MIMIV
Sequence: MSKTITKKVNKKTKKSTKINPKKLAKKPIIKSIDKPTNLTDVDFDKLIHTVETSTKRHFIAIEFNKKPVNNIANLGAKVNQKARLERSGEYYGIGVEILETIRPLLTNRLIIKILKLLKQENLTSPLKILDLNSLDELHYVLHCWLENATTVYDDCLNSYDKSYPEYDQWIRTVRSDPLNCKVRLTEIGFNEKTGGSVVPADWIDGEFDSGISLHKEMDKLETRIGKPPATYAIIHSMMIQKQDSIIEDITNTKFDYLFYVDLIDNKLVSKLVSKIRKKPYQYVKYDNTIIGFCLEDILTTKSQNNKKPREVGLYVSRLQKSIRRGRFGSQIMRETIDAINESPNYNLPEHGFMRVSASKQLVWRLFISILEDCRPYVTSGNELSLLDLILLVLITQKCLEYKFTDNLLELIKVTALMAQYNDTKSDLFDWRKFTESIKTPINPKSDYHTAISLALGNVIMMSGDTRMLKKLYSVNLVFKEFKRPKCNSLLELTSSNFKLTDQDTYQDIMLTSIDHHCKPNIILYYQACIPVSLTTREISSYIWKISSSYNIRSGKTQNNIDQVLRLVQNFLLEKSTKVSNEINNTFLNYSCNEIEPDNKTRRTSFLILFGSKYKFGGKDVMLAGTKKNPVKIKTKNEWVYSKDMAVINAYPKKYIYTKYLDPPFGFKWTKPKFWTEIIDGKPYVDGTNVDFFDGSIALKSITPLVTKKCNKYTTSLITTFFSGLDIELESILDVRNKSKPQIVNWVNTIDLNDIDLELVRCTYTKIFNQFNNTIMIGPCDRSGNKMHNSINYKLEGKLWAIFNLLHYLYPKTINPNSALNFSLNRSTQGYIHLIKSLEQLLFVGKNITGLVPTISTKLWDHQQETVNTMVAKFTDGYHGFGDASDVGSGKTLTSLALASKLINTINDIHSGILVLLPGNKLIVTWQDEIDKHTKNFDVKLHKPSGDIGKIKRNTIVISTMGRQRDNPINHKWLLVIIDECLSVQNKNALQTEQAFIQSLLAKYLVMMSATFFRTRFDKLYYMLKMLQTGLPERKQYLETILAESIVAKVPLSGMKWTTNIIHFQLNSLTRELYNKIIDKDLSVEAKYAKLNSLLVNNKEVNNMVVKQLSKLIAELTKQGCKCLIYARSQDEAKLWSNNLKIPIYPKKGDHCIVTYHDGTYGLNDLVIYNTIVMRPPTPDSLPQIKGRLARPGQKNNNLRIEYFVLEDTIEEGLLIRLEIASKFVHQYIMPLAKFYNISVNHQKYK
What are the official names of this protein?
Putative helicase L115.
Protein: RISB_BACAH
Sequence: MVFEGHLVGTGLKVGVVVGRFNEFITSKLLGGALDGLKRHGVEENDIDVAWVPGAFEIPLIAKKMANSGKYDAVITLGTVIRGATTHYDYVCNEVAKGVASLSLQTDIPVIFGVLTTETIEQAIERAGTKAGNKGYESAVAAIEMAHLSKQWA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: RNC_MYCGE
Sequence: MKNKVLKLKNNKIFDKKLATFLKNLDIFPNNWEFFEKAFIHASYINEHEDVSESYDRLEFLGDALIDFVVAKKLFELYPKYNEGLLTRTKIEIVKGENLNRIGMELKLGDFVKLSNGAELTENTVGDVLEALVGAIYEDMGMKKATEFVEKYIFERTFSEILKYDFFSLFQEQKLPEPRVRVSLTSNNLVLSIIELDGDIIWSQAIPNNKNYDDKSVLEHNAMASFTSFLKSSKGSHFFSDLKEKIENQKMCKKLAIKPKKN
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAX_RHOJR
Sequence: MLLTVDVRNTNIVLGLFTGSGEHSKLVQDWRMRTDARMTADELALIFRGLLGAHTDQITGVSALSTVPSVLREIRVMLTRYWGHVPHVLVEPGVRTGVPLLVDNPKEVGADRIVNSLAAHHLYDAPCIVVDFGTSTCVDVVSAKGEFLGGAIAPGLEISSDALASQSAALRKVELVRPRSVVGKNTVECMQSGAVFGFAGLVDGLVRRVRKELPAFSGSDVVVIATGDRAPLIMPETETVDEHEPDLTLEGLRLVYERNQARRGARRSPLE
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPH_DESVV
Sequence: MNVIRARTAGFCMGVSLALRKLDREVDRAEEKAAQGSPRCRIATFGPIIHNPQVLEAYAGMGVRCLRQVDEVEAGDHVVIRAHGVPQQQEKALRSRDAVVVDATCPKVKKAQLGIEEQCRAGRTLLLFGEAEHPEVRGLLSYAGEGALVFGSVDELEGLPLQPETEYFLAAQTTQDRVAFEAARAWLHERLGHEVPVLETICDATRLRQQEAIDIARKVDAMVVVGGFDSGNTRRLADVAAAQGVFTVHVENESQLPVEQLRGCGIIGLTAGASTPKSIIDATQRFLESL
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: RL31_METMJ
Sequence: MAEALKEHIYIIPLREVKRAPRWKRGNTAIKDIRAFLVRHMKSEDVKLDKSINEKVWENGSSKPPRKIRVRAMKFEDGQVQAELAEE
What are the official names of this protein?
50S ribosomal protein L31e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL31 family.