PharMolix/UniProtQA huggingface dataset:
Protein: METK_MYCVP
Sequence: MSDARLFTSESVTEGHPDKICDAISDSVLDALLADDPKSRVAVETLVTTGQVHVVGEVTTTAKAAFADITNTVRERILEIGYDHSDKGFDGLTCGVNIGIGKQSPDIAQGVDTAHETRVEGAADPLDSQGAGDQGLMFGYAIADTPELMPLPIALAHRLSRKLTEVRKNGTLDYLRPDGKTQVTVQYDGTTPVRLDTVVLSTQHADGIDLESQLAPEIKQHVIDAVLTELGHDTLDTSAPRILVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVAKNVVAAGLAQRVEVQVAYAIGKAAPVGLFVETFGSETVDPVKIQKAIGEVFDLRPGAIVRDLDLLRPIYAPTAAYGHFGRTDIELPWEQLDKVDDLKAAV
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y889_HELPY
Sequence: MLKTYHIALACVILAVVVLLFGGESLSLEEWQEVCLNVKNHFLHNEELSSLSIIILEIRLPRVILALLVGASLSGSGVVMQTIFRNPLVDPFLLGISSGAMLGVAMAIAVVESNIAILAFFGAILASLAVLAMNRVLGNSVLSLVLSGVVLSAFLSALAGAIKFFVIPQKAQAIVVWLLGSLSLSSYKDCLIAFIGLSLGFIPLFLLRWRINLLSLSDAQSLSLGINPVLLRSLCLVCVSVASALAVSVSGTIGWIGLVIPHVARLFFGANLQKLLLSSLLMGAFFLLLADVVAKTITPYDLPVGIATSVLGAPFFLWLLFRTRGV
What is the function of this protein?
Part of a binding-protein-dependent transport system for an iron chelatin; probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Probable iron chelatin transport system permease protein HP_0889.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HISX_XANOR
Sequence: MKILDWSQLDVAARTDALTRPVQTVAAQTRNAVAALIADVRTRGDAALREITARFDGVSLERFAVSEAEFAAAEAAVAPELRQAMQDAVARIDTFHRAGMSEGYAVETAPGVVCEKIVRPIGRVGLYVPAGSAPLPSTALMLGVPARLAGCRAVVLCTPPRKDGSVDPAVLVAAWLTGVRRVFKLGGAQAIAAMAYGTESVPSCDKLFGPGNSYVTEAKQQVAQSGAAAIDMPAGPSEVLVIADAGAQAAFVAADLLSQAEHGADSQVLLLSDSDVLIDAVQAQLEIQLAHLSRADIARQALAQSRLIKVQTLDEAFAISNRYAPEHLILALREPRAWLAQVEAAGSVFLGDYTPEALGDYCSGTNHVLPTSGAARAYSGVSVASFQNMFSVQAASKAGIAGIGECALILARAEGLDAHANAVALRMGVAA
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: CAV1_MUSPF
Sequence: MSGGKYVDSEGHLYTVPIREQGNIYKPNNKAMAEEINEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQCVSRVYSIYVHTFCDPFFEAVGKIFSSIRINMQKEI
What is the function of this protein?
May act as a scaffolding protein within caveolar membranes.  Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation.  Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity).  Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity).  Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation.  Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner (By similarity).  Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway (By similarity).  Negatively regulates TGFB1-mediated activation of SMAD2/3 by mediating the internalization of TGFBR1 from membrane rafts leading to its subsequent degradation (By similarity).
What are the official names of this protein?
Caveolin-1.
What is the protein family that this protein belongs to?
Belongs to the caveolin family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Membrane raft. Note=Colocalized with DPP4 in membrane rafts. Potential hairpin-like structure in the membrane. Membrane protein of caveolae (By similarity).
Protein: LXN_MOUSE
Sequence: MEIPPTHYAASRAASVAENCINYQQGTPHKLFLVQTVQQASKEDIPGRGHKYHLKFSVEEIIQKQVTVNCTAEVLYPQMGQGSAPEVNFTFEGEIGKNPDEEDNTFYQSLMSLKRPLEAQDIPDNFGNVSPQMKPVQHLAWVACGYVMWQNSTEDTWYKMLKIQTVKQVQRNDDFIELDYTILLHDIASQEIIPWQMQVLWHPQYGTKVKHNSRLPKEGQAE
What is the function of this protein?
Hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4 (By similarity).  May play a role in inflammation.
What are the official names of this protein?
Latexin, Endogenous carboxypeptidase inhibitor, ECI, Tissue carboxypeptidase inhibitor, TCI.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I47 (latexin) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VL2_HPV50
Sequence: MLRRRKRASPTDLYRSCLQGGDCIPDVQNKFEGNTIADWLLKIFGGLVYFGNLGIGTGRGTGGTFGYRPFGAPGSGRPTQELPIARPNVVIDPLGPAPIVPVDPSAASIVPLVEGAPDVGFAAPDAGPAAGGTDIELYTITNSTTDVGAVGGGPTVTSNEEFEVAVIDAQPIAPYPKQLLYDSTIAATFETQINPFINPDINNVNVLVDPSFAGDTVGDYFYEEIPLERLDIQTFDILEPPTESTPTQLGNRFVSRARDLYSRFVAQQPISEPDFLSQPSRLVQFEYRNPAFDPDVSLYFERDLEGLRAAPLQEFADVVYLGRPRVSSTSEGTIRVSRLGTRAALTTRSGLSVGPQVHFYMDLSDIPPEDSIELHTLNVTPQTSTIVDDILATTTFDDPANSLFTQFNEDVLTDDVEHNFTESHLVIPATDEENDTAINIINLRNIPLTVGMNSGDISTTLSDYNILDASLIVKSNVSEQPLFVLDYSDYDLHPGLLPKRRRIDYF
What is the function of this protein?
Minor protein of the capsid that localizes along the inner surface of the virion, within the central cavities beneath the L1 pentamers.  Plays a role in capsid stabilization through interaction with the major capsid protein L1.  Once the virion enters the host cell, L2 escorts the genomic DNA into the nucleus by promoting escape from the endosomal compartments and traffic through the host Golgi network.  Mechanistically, the C-terminus of L2 possesses a cell-penetrating peptide that protudes from the host endosome, interacts with host cytoplasmic retromer cargo and thereby mediates the capsid delivery to the host trans-Golgi network.  Plays a role through its interaction with host dynein in the intracellular microtubule-dependent transport of viral capsid toward the nucleus.  Mediates the viral genome import into the nucleus through binding to host importins.  Once within the nucleus, L2 localizes viral genomes to host PML bodies in order to activate early gene expression for establishment of infection.  Later on, promotes late gene expression by interacting with the viral E2 protein and by inhibiting its transcriptional activation functions.  During virion assembly, encapsidates the genome by direct interaction with the viral DNA.
What are the official names of this protein?
Minor capsid protein L2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L2 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host early endosome. Host Golgi apparatus.
Protein: Y5128_DICDI
Sequence: MKNYNFILISLFIIFFIILNISSNNNNFTNAEEMTGINDIINRRYQEYMENRTPNEQQQQQQQQQNNNNPPQHIDPLVGNPCNHDQIMQGRISKLKEKLKKDQQNQQQN
What are the official names of this protein?
Putative uncharacterized protein DDB_G0282065.
What are the subcellular locations of this protein?
Secreted.
Protein: Y2569_MYCTO
Sequence: MSADSSLSLPLSGTHRYRVTHRTEYRYSDVVTSSYGRGFLTPRNSLRQRCVAHRLTIDPAPADRSTSRDGYGNISSYFHVTEPHRTLTITSDSIVDVSPPPPGLYTSGPALQPWEAARPAGLPGSLATEFTLDLNPPEITDAVREYAAPSFLPKRPLVEVLRDLASRIYTDFTYRSGSTTISTGVNEVLLAREGVCQDFARLAIACLRANGLAACYVSGYLATDPPPGKDRMIGIDATHAWASVWTPQQPGRFEWLGLDPTNDQLVDQRYIVVGRGRDYADVPPLRGIIYTNSENSVIDVSVDVVPFEGDALHA
What are the official names of this protein?
Uncharacterized protein MT2645.
What is the protein family that this protein belongs to?
To M.leprae ML0607.
Protein: TM9S3_HUMAN
Sequence: MRPLPGALGVAAAAALWLLLLLLPRTRADEHEHTYQDKEEVVLWMNTVGPYHNRQETYKYFSLPFCVGSKKSISHYHETLGEALQGVELEFSGLDIKFKDDVMPATYCEIDLDKEKRDAFVYAIKNHYWYQMYIDDLPIWGIVGEADENGEDYYLWTYKKLEIGFNGNRIVDVNLTSEGKVKLVPNTKIQMSYSVKWKKSDVKFEDRFDKYLDPSFFQHRIHWFSIFNSFMMVIFLVGLVSMILMRTLRKDYARYSKEEEMDDMDRDLGDEYGWKQVHGDVFRPSSHPLIFSSLIGSGCQIFAVSLIVIIVAMIEDLYTERGSMLSTAIFVYAATSPVNGYFGGSLYARQGGRRWIKQMFIGAFLIPAMVCGTAFFINFIAIYYHASRAIPFGTMVAVCCICFFVILPLNLVGTILGRNLSGQPNFPCRVNAVPRPIPEKKWFMEPAVIVCLGGILPFGSIFIEMYFIFTSFWAYKIYYVYGFMMLVLVILCIVTVCVTIVCTYFLLNAEDYRWQWTSFLSAASTAIYVYMYSFYYYFFKTKMYGLFQTSFYFGYMAVFSTALGIMCGAIGYMGTSAFVRKIYTNVKID
What are the official names of this protein?
Transmembrane 9 superfamily member 3, EP70-P-iso, SM-11044-binding protein.
What is the protein family that this protein belongs to?
Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FAL1_CANGA
Sequence: MSFNREHDLKLKFKSSKKLKISATFESMDLKEGLLRGIYSYGFEAPSAIQSRAITQIISGKDVIAQAQSGTGKTATFTIGMLQAIDLKKHDLQALVLSPTRELAAQIGKVVTNLGDYMNVKAYAMTGGKTMKDDLKKIQKHGCQVISGTPGRVLDMIKRRLIETRHVQILVLDEADELLSDTLGFKHQIYDIFTKLPRTSQVVVVSATMSPEILEITKKFMNDPVKILVKRDEITLEGIKQYYVNVEKEEWKFDTLCDIYDSLTITQCVIFCNSKKKVDWLAHKLKQSNFAVISMHGDMKQDERDRVMNEFRTGQSRVLISTDVWARGIDVQQVSLVINYDLPEITENYVHRIGRSGRFGRKGVAINFLTKIDASRMKEIEKYYKIKVKPMPADLSELS
What is the function of this protein?
ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis.  Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase FAL1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX48/FAL1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RECA_CHLAB
Sequence: MNVPDRKKALEAAIAYIEKQFGSGSIMSLGKHSASHEISTIKTGALSLDLALGIGGVPKGRIVEIFGPESSGKTTLATHIVANAQKMGGVAAYIDAEHALDPSYASLIGANIHDLMISQPDCGEDALSIAELLARSGAVDVIVIDSVAALVPKSELEGDIGDVHVGLQARMMSQALRKLTATLARSQTCAIFINQIREKIGVSFGNPETTTGGRALKFYSSIRIDIRRIGAIKGNESFDLGNRIKVKVAKNKLAPPFKTAEFDILFNEGISSAGCILDLAVEHNIVEKKGSWFNYQDRKLGQGREAVREELKKNKKLLEELEKRILEVTASPKTIVEEKKEELAMQPVA
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATE_METBF
Sequence: MGLEIVVKDIQEGASAEVSRIKAEGDAKASEIINEAKEVQKKTLGDSLAKAEEDLQNLHQQVISSANLEVKRITLNKRKDLLDKVYVQTVEKIKSMPASKKEELLKNILSKYEASGARVYSSKDSEDIVKKLTSLSYAGNLDAIGGIVLENEDGTVRLDFTYDSILKNVYERSLKQISDLLYG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: SAMP_MOUSE
Sequence: MDKLLLWMFVFTSLLSEAFCQTDLKRKVFVFPRESETDHVKLIPHLEKPLQNFTLCFRTYSDLSRSQSLFSYSVKGRDNELLIYKEKVGEYSLYIGQSKVTVRGMEEYLSPVHLCTTWESSSGIVEFWVNGKPWVKKSLQREYTVKAPPSIVLGQEQDNYGGGFQRSQSFVGEFSDLYMWDYVLTPQDILFVYRDSPVNPNILNWQALNYEINGYVVIRPRVWD
What are the official names of this protein?
Serum amyloid P-component, SAP.
What is the protein family that this protein belongs to?
Belongs to the pentraxin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SAE2B_XENLA
Sequence: MAVIGALPKEVAEAVSASRLLVVGAGGIGCELLKNLVLTGFTNLDVIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFCPDASITAYHDSIMNPDYNVEFFKQFTMAMNALDNNAARNHVNRMCLAAGIPLIESGTAGYLGQVSVIKKGVTECYECQPKPTQKTFPGCTIRNTPSEPIHCIVWAKYLFNQLFGEEDADQEVAPDIADPEAAWDPTKAAERANASNVDGDIKRVSTKQWAKSTGYDPIKLFNKLFRDDIKYLLTMDRLWRKRKPPIPLEWASLHNKENCSEIQNESSLLGLKDQKVLNVASYAQLFSKSVETLREQLREKGDGAELVWDKDDVPAMDFVTAAANLRMHIFSMNMKSKFDVKSMAGNIIPAIATTNAVISGLIVLEGLKILSGNTEQCRTVFLNKQPNPRKKLLVPCSLDPPNPSCYVCAIKPEVTVKLNVHKVTVQMLQDKILKEKFAMVAPDVQIEDGKGTILISSEAGETDANNHRKISEFGIRNSSQLQADDFLQDYTLMMNILHSDEMEKDVDFEVVGDVPEKGPQKPPEESVKNITNGSDDGAQPSTSKAQDQDDVLIVDSDEESPSSSNADVGMESASLKRKLPDEEAVSSTKRKRIEPPVEEDDDIIALD
What is the function of this protein?
The heterodimer acts as an E1 ligase for sumo1, sumo2, and sumo3.  It mediates ATP-dependent activation of sumo proteins followed by formation of a thioester bond between a sumo protein and a conserved active site cysteine residue on uba2/sae2 (By similarity).
What are the official names of this protein?
SUMO-activating enzyme subunit 2-B, Ubiquitin-like 1-activating enzyme E1B-B, Ubiquitin-like modifier-activating enzyme 2-B.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-activating E1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYT_VIBCH
Sequence: MPIITLPDGSQRHFDNPVSTLEVAQSIGPGLAKATIAGRVNGARVDACDLIEHDASLEIITTKDEVDGLEIVRHSCAHLLGHALKQLYPNAKMAIGPTIDSGFYYDIDLEQSLSQEDLEKIEARMVELAKTKYAVVKKKVSWQEARDTFESRGESYKMEILDENVARDDRPGLYHHEEYIDMCRGPHVPHMGFCQNFKLLNIAGAYWRGNSDNKMLQRIYGTAFHDKKALQAHLTRLEEAAKRDHRKIGKQLDLFHMQQEAPGMVFWHHNGWSIFRDLEIFIRQKLNEYGYQEVKGPLMMDRVLWERSGHWDKYADAMFTTSSENREYAIKPMNCPGHIQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGIMRVRGFTQDDAHIFCTEDQIQQEVTSCIKMVYDTYTTFGFQNIVVKLSTRPEKRVGSDEIWDKSEQALIDSLKAMDIPFEIQEGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFNLPTRLGATYVGESNERLIPVMIHRAILGSLERFIGILIEEYAGFFPTWLAPEQAVVVNITDKQADYAHEVAQKLQKCGIRAKADLRNEKIGFKIREHTLKRVPYMLVCGDQEMEAGEIAVRTRKGKDLGKFKLDDFIAHIQAEIASRKLNLEE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SVH2_CAEEL
Sequence: MVLGSSQSSAKELTTQSSIFRFLVLLLCFTSATGGQINGKLLNGNGVFVSRDELQNKNVLGVITGFDLLVVATHSRFQVFENNEERRTVGHVSLDMHPRTKFLELKLFSKSEIFYCDESSCGLCTYSGVTSSCSTFMLNGDEPKIQEILSSSAVKIENLGQIMLAISFKNEEDPDNPRTMILRYNAQDTGTVIPTAYHADSSFIHNNHALTGFEREGFVYFVMTASQIFEPEVFLHDQSNNKVTVTKVIRFCATDQTADLASKISILVGCDQEFRNISSRGETAVYDHANDLINIVMFNHTSMNHLMCRFKMANIEKRFKTIWSTCQETSFSGSTAKTTRCKYPQIFDQMKVKKGCLTYSRLDDESSPTLCVRYGRGDALDNCQLHTAKSNSYRYGWLEDYNVLQGELMMRIPYPFFGIAESLITDGKSYFAAVSGEFDMSDVLRFSASESADIRPHWRTNISVVGKFSITKTKENQLLYTTVEGLQSLDISCKGLYPNCQTLRQGGWEDPLECSWCADDNAQRTITSSEVSSCKNNLKHECPPSMRWIHKYNNNSGFTAVVDGFRALKNPKLNACGTNCVVTVVDSSSIQCDTNPDEVIGDSCKQVFLSGMIGDKNYSFPFDYQQADRGTQTDVKNSQVDDKKGSSPGWKIAIAIISVMTIILIVAIIVYYMRNRFPRIKTHVRPPIGQRIENEYDMGHMAGRQAQLAINGDNYVKVFRSMRPDLKVDFKNLRVDKLDPIGQGHYGVVYKAMYSPSKSLEEKVVCKYLKEGKISEFYEEARTMSEFDHPNILKLIGVALDDSSHLPIIITEYMAKGDLKSFIENVENTIKMRDLFEFAFDIAKGMNYMHSKKFIHRDLACRNCLLDEHLRVKIADFGLCRKVDIETELYVQMHERDLPVRWFPPEISEQGFGITSDIWSFGVVIWELFTRGSTPYSNMASWILILPWLKESETNRLRKPPYCPEKLYTDVMLACWKANPAERPQFSDLVTIIPNVVKYMEGYDRSQLQAGYERVSSRFLSLSRHDPAFPIYQNEMPNTPLLANCQNDTNDSKTLAELPSDSPSTSTAIPQSTPYQLLSECSETSV
What is the function of this protein?
Receptor tyrosine kinase which may phosphorylate mlk-1, a component of the mlk-1, mek-1 and kgb-1 pathway (PubMed:22388962).  Involved in axon regeneration after injury by promoting the generation of productive and stable growth cones (PubMed:22388962, PubMed:27984580, PubMed:31109965).
What are the official names of this protein?
Tyrosine-protein kinase receptor svh-2, Met/Ron-like receptor tyrosine kinase svh-2, Suppressor of vhp-1 deletion lethality protein svh-2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: MATK_OENEH
Sequence: MEEFPGYFELDRSRQHDFLYPLIFRESIYALAHDHGLNRNRSTLFENEVDYDKKYSLIIVKRLITRMYQRNHLIISANGSVQNPFWGHNQNLYSKILSEGFAVIVEIPFSLRVLSSFERKEKDIAKSPTLRSIHSIFPFLEDQFSHLDYLSHVLIPYPIHLEIAVQTLRYWVKDASSLHLLRIFLHEYWNSFSTPKKHITLFLKGNSRFFLFLYNSYVCEYESIFLFIRNQSSHFQSTSSGVFFERILFYVKIDHLVEVFVGTDFLDIRSFFKDPNMHYVRYQGKSILASKDTPLLMNKWKYYLVNLWQYHFSVWSQPGRININQLGKYSLDFLGYFSNVQLKSSVVRNQTLENSFLINNAMKKLETTVPILPLIGSLSRAKFCNALGHPISKPTRNDSSDSDIIDRFVRICRNLSHYHSGSSKKKSLYRIKYILRLSCVKTLARKHKSSVRAFLKRLGSELGDEFLTEEGVVLAVIFPKASGRLYRGRIWYLDIPCINDRVGDAEGSIFTK
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SYH_BRUMB
Sequence: MADKADKMKARLPRGFVDRVPDDLRAAEKMMATIREVYDLYGFEPVETPLVEYTDALGKFLPDQDRPNEGVFSFQDDDEQWLSLRYDLTAPLARYVAENFETLPKPYRSYRNGWVFRNEKPGPGRFRQFMQFDADTVGAPNVSADAEMCMMMADTLERLGIQRGDYAIRVNNRKVLDGVLDAIGLEGEGNAAKRLNVLRAIDKLDKFGPEGVRLLLGKGRLDESGDFTKGAQLPEAAIEKVLAFTAAGGADGAQTIANLQAVVAGNAKGEEGVQELADMQALFFAGGYEGRVKIDPSVVRGLEYYTGPVFEAELLFDVTNEDGQKVVFGSVGGGGRYDGLVSRFRGEPVPATGFSIGVSRLMTALKNLGKLDVSDTVGPVVVLVMDKDTQNLSRYQKMVSDLRKAGIRAEMYVGGSGMKAQMKYADRRAAPCVVIQGSQEREAGEVQIKDLVEGKRLSAEIEDNVTWRESRPAQITVREDGLVDAVREILDAQARDRAEQSK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHYSP_TRYB2
Sequence: MSGVPFPSRVIGDLDYSNLLNIGQEEAIRCVLNAYPNIGLEATNLGRARRIVQRALNDNGMDGNKVMLAYTSNLISSGLRDTFACLARENRIGAVVTTAGGVEEDVIKCLGDTLVGDFALNDHALRNNGLNRVGNLLVPNDNYRNFEDFFVPLLRRLHEQQRDSRWTTKTTPSQIIAEIGAALESVRPNDCGSSLIYWCYRNDIPVFSPAFTDGSMGDMIYFYNYSRKGLVVDPVPDVRRLRQLGCKSTNVGRITCIVLGAGLPKHHLLRNVQADAVVYVTTGSDADGCESSCNVMADRANGLLSPNCDVVRVHGDATIISPLLLLRSSDGKEKVGVREDGN
What is the function of this protein?
Required for the activation and stability of deoxyhypusine synthase DHSc.  Required for cell growth and survival.
What are the official names of this protein?
Deoxyhypusine synthase regulatory subunit, Inactive deoxyhypusine synthase.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine synthase family.
Protein: CLAA_PENCR
Sequence: MLLQPESSSKPRNDSPPGFKFHSSCDTCLKAKIKCSQAKPTCARCLQQGRQCVYSPYRKIGRPSTKNLPLDQLQQPKGRTAGGTARRSLSRRVSLASPGIENGSRVGNVRHATNRVLHAQESVLVPSQTWSDQELTGNINRLDYGLEGTNWSALEGLLDASMSTLPQADHELASAVPRLDQVHDLDPNPGQEDLTGYLSPSSLSSRESLATTFPPEAEAGSFGLSSEFPFSAGYSLGTGPVLSESLNAFPVLSSFPSSASSPVTEARGFNLLSAPTDRCTFQCYPVLINILNDMNEFQRKSSGLPLDVLLNLDKRVRKVHETILGCPCCLVSCAAALTLMLITMVNINLLSLFERSCGSTDGGSGSSMSRGELNVAPRIAFGGGNYAGQDRSRNPLPYTTGHLTLGNIHLDETVKLVFSRRLVRLYLERQLGVVQQLSQLLGRVEGDGASIKVTQDLLRDQLRRLEHFVGFITLTD
What is the function of this protein?
Transcriptional regulator; part of the cla gene cluster that produces clavatol and ortho-quinone methide (PubMed:30811183).  The clavatol biosynthesis cluster cla and the terrestric acid cluster tra are both involved in the production of peniphenones and penilactones (PubMed:30811183).
What are the official names of this protein?
Transcriptional regulator claA, Clavatol biosynthesis cluster protein A.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL20_AMOA5
Sequence: MPRSVNAVASRARRKRVIKLAKGYWGRRKNAWTIAKNAVERALQYAYRDRKAKKREFRRLWIQRINAAAKMNGLSYSQFMGKLAASGIELNRKVLADLAMNNPEAFKEILKKVA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: CHMO_ACISP
Sequence: MSQKMDFDAIVIGGGFGGLYAVKKLRDELELKVQAFDKATDVAGTWYWNRYPGALTDTETHLYCYSWDKELLQSLEIKKKYVQGPDVRKYLQQVAEKHDLKKSYQFNTAVQSAHYNEADALWEVTTEYGDKYTARFLITALGLLSAPNLPNIKGINQFKGELHHTSRWPDDVSFEGKRVGVIGTGSTGVQVITAVAPLAKHLTVFQRSAQYSVPIGNDPLSEEDVKKIKDNYDKSLGWCMNSALAFALNESTVPAMSVSAEERKAVFEKAWQTGGGFRFMFETFGDIATNMEANIEAQNFIKGKIAEIVKDPAIAQKLMPQDLYAKRPLCDSGYYNTFNRDNVRLEDVKANPIVEITENGVKLENGDFVELDMLICATGFDAVDGNYVRMDIQGKNGLAMKDYWKEGPSSYMGVTVNNYPNMFMVLGPNGPFTNLPPSIESQVEWISDTIQYTVENNVESIEATKEAEEQWTQTCANIAEMTLFPKAQSWIFGANIPGKKNTVYFYLGGLKEYRTCASNCKNHAYEGFDIQLQRSDIKQPANA
What are the official names of this protein?
Cyclohexanone 1,2-monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the FAD-binding monooxygenase family.
Protein: TONB_VIBCH
Sequence: MNLNRYVIAGGLSLAFHALLLITTDEAQVFAMPAGNPTQSVSINMVSMPKVAPAQPEQTQTEQSKPESVKPTPVQEVVKTPPAKPKVKPHKPKPQTVKKPVPAEQVPSKSVAKPQPEKVERTAETAQKPAPTPNQQPSQPTAASQGITSQPILVDKPALVSAQVQPRYPRIARKRGIEGTVMYEIWLDAQGNQIKQQLLSSSGTEALDQSALEAIKQWKFSPHILDGVPVAHRIHIPIRFKLEG
What is the function of this protein?
Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates.  It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins (By similarity).
What are the official names of this protein?
Protein TonB.
What is the protein family that this protein belongs to?
Belongs to the TonB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein; Periplasmic side.
Protein: MSRQ_PSESM
Sequence: MRYPFWRLAVFLAACVAPVWWLYQAWIFALGPDPGKVLVENFGLATLVMLLITLAMTPLQRLTGWPGWIVVRRQLGLWCFAYVVLHMTMYALFILGLDWGQLGVELVKRPYIIVGALAFLGLLALAVTSNRYSQRRLGSRWKKLHRLVYVILGLGLLHMFWIVRADLKEWALYAGIGAILLLLRVPMIARRIPRLGGAAKAGSIKVQNNG
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation.  MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ, Flavocytochrome MsrQ.
What is the protein family that this protein belongs to?
Belongs to the MsrQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.