PharMolix/UniProtQA huggingface dataset:
Protein: MYH4_HUMAN
Sequence: MSSDSEMAIFGEAAPFLRKSEKERIEAQNKPFDAKTSVFVVDPKESYVKAIVQSREGGKVTAKTEAGATVTVKEDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEPASGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELIEMLLITTNPYDFAFVSQGEITVPSIDDQEELMATDSAVDILGFTADEKVAIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLTSLNSADLLKSLCYPRVKVGNEFVTKGQTVQQVYNAVGALAKAIYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLAFLFSGAQTAEAEGGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLAQLITRTQAICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQVNKLRVKSREVHTKVISEE
What is the function of this protein?
Muscle contraction.
What are the official names of this protein?
Myosin-4, Myosin heavy chain 2b, MyHC-2b, Myosin heavy chain 4, Myosin heavy chain IIb, MyHC-IIb, Myosin heavy chain, skeletal muscle, fetal.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril. Note=Thick filaments of the myofibrils.
Protein: HIS3_RHOPT
Sequence: MSSESRSASSPVAPDDIEEGVVLRPKFDAHGLVTVVATDARTGDVLMVAFMNDEALDRTIQTGEAWYYSRSRKRLWKKGETSGHIQKVLEMRVDCDQDAVWIKVDQTGGAACHTGRHSCFYRRIDRGGDGAPVLIETDAERKFDPDKVYGK
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_LISMF
Sequence: MKVIFLKDVKGKGKKGETKNVADGYANNFLIKNGYAVEANNAALSTLSAQKKKEDKLAAEELAEAKALKEKMENLTVELKAKSGEGGRLFGSITSKQIAQTLEKTHGIKIDKRKMDLPEAIRALGHTKVPVKLHHEVTATLDVHVSEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: NDUS2_DICDI
Sequence: MLNISKIFEEVKVMKNFTLNFGPQHPAAHGVLRLIVELESENVVRVEPHIGLLHRGTEKLIEGKTYTQALPYFDRLDYVSMNVQEHAYSLAVERLYLDSLDIELEIPQRAKVIRVLFSEITRVLNHIMATTTHAMDVGALTPFLWAFEEREKLMEFYERVSGARMHAAYIRPGGVAFDLPMNISEDIYKFVIQYRKRLEEIEDMLINNRIWKQRLVDIGIVSAEEALNYGFTGPLLRGAGIVYDIRKNYPYDDYDKYDFKIIIGEENNSYTRFIIRMKEMYQSLSIIEQALNNLRPGLIKLEGVNITAPDRAFVKKDMESCINHFKFFSEGFIIPANENYTIVEAPKGEFGIYLNANDTAKPYRCRIKAPGFLHLQGLNMMSKDHLLADVVTLIGTQDIVFGEVDR
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase 49 kDa subunit, NADH dehydrogenase subunit 7.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: Y1053_METJA
Sequence: MIPLVPTSKTEIDKLEHVLILGTLFRPEILELIKDPIEKVTWVDSLAIAAGALAREKAGYTIREIADELGRTEQTIRKHLKGETKAGKLVRETYEMMKRGELNIEEVEKFLEAVVRKEELEKITDIKKLEEEIEKLKKENEELAAKLEKVKEKLKEVLSELEK
What are the official names of this protein?
Uncharacterized protein MJ1053.
Protein: PSBD_TRICV
Sequence: MTIAIGQNQERGLFDLIDDWLKKDRFVFIGWSGLLLFPTAYLAAGGWMTGTTFVTSWYTHGLASSYLEGCNFLTAAVSTPANSMGHSLLLLWGPEAQGDFTRWCQIGGLWAFIALHGAFGLIGFCLRQFEIARLVGIRPYNAIAFSGPIAVFVSVFLLYPLGQASWFFAPSFGVAAIFRFLLFLQGFHNWTLNPFHMMGVAGILGGALLCAIHGATVENTLFEDGDAANTFRAFTPTQSEETYSMVTANRFWSQIFGVAFSNKRWLHFFMLFVPVTGLWTSAIGIVGLALNLRAYDFVSQELRAAEDPEFETFYTKNILLNEGIRAWMAAQDQPHENFVFPEEVLPRGNAL
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.  D2 is needed for assembly of a stable PSII complex.
What are the official names of this protein?
Photosystem II D2 protein, PSII D2 protein, Photosystem Q(A) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ARNE_ECOLU
Sequence: MIWLTLVFASLLSVAGQLCQKQATCFVAINKRRKHIVLWLGLALACLGLAMVLWLLVLQNVPVGIAYPMLSLNFVWVTLAAVKLWHEPVSPRHWCGVAFIIGGIVILGSTV
What is the function of this protein?
Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
What are the official names of this protein?
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE, L-Ara4N-phosphoundecaprenol flippase subunit ArnE, Undecaprenyl phosphate-aminoarabinose flippase subunit ArnE.
What is the protein family that this protein belongs to?
Belongs to the ArnE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GCSP_SALPB
Sequence: MTQTLSQLENRGAFIERHIGPDAAQQQEMLNAVGAESLNALTGQIVPKDIQLATPPQVGEAATEYAALAELKAIAGRNKRFTSYIGMGYTAVQLPPVILRNMLENPGWYTAYTPYQPEVSQGRLEALLNFQQITLDLTGLDMASASLLDEATAAAEAMAMAKRVSKLKNANRFFVASDVHPQTLDVVRTRAETFGFDVIVDDAAKALDHQDVFGVLLQQVGTTGEIHDYGALISELKARKVIVSVAADFMALVLLTAPGKQGADIVFGSAQRFGVPMGYGGPHAAFFAAKDEFKRSMPGRIIGVSKDAAGNTALRMAMQTREQHIRREKANSNICTSQVLLANIASLYAVYHGPVGLKRIANRIHRLTDILAAGLQQKGLKLRHAHYFDTLCVEVADKAAVLARAEAAEINLRSDIHNAVGITLDETTTRENVAQLFNVLLGDSHGLNIETLDKDVALDSRSIQQSMLRDDAILTHPVFNRYHSETEMMRYMHSLERKDLALNQAMIPLGSCTMKLNAAAEMIPITWPEFAELHPFCPPEQAEGYHQMISQLSDWLVKLTGYDAVCMQPNSGAQGEYAGLLAIRHYHESRNEGHRDICLIPASAHGTNPASAHMAGMQVVVVACDKNGNIDLDDLRAKAEQHAANLSCIMVTYPSTHGVYEETIREVCEVVHQFGGQVYLDGANMNAQVGITSPGFIGADVSHLNLHKTFCIPHGGGGPGMGPIGVKAHLAPFVPGHSVVQIEGMLTRQGAVSAAPFGSASILPISWMYIRMMGAEGLKQASQVAILNANYIASRLKDAYPVLYTGRDGRVAHECILDIRPLKEETGISELDIAKRLIDYGFHAPTMSFPVAGTLMVEPTESEGKAELDRFIDAMLAIRAEIDQVKAGVWPLEDNPLVNAPHIQSELVAEWAHPYSREVAVFPAGVADKYWPTVKRLDDVYGDRNLFCSCVPISDYQ
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: ATP8_CORCN
Sequence: MPQLNPNPWFYIMLMSWLTFSLIIQPKLLSFTSANPPSNKTSTTTRTLPWTWPWT
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: RL15_HAEIN
Sequence: MRLNTLSPAEGAKHSAKRLGRGIGSGLGKTGGRGHKGQKSRTGGGVRRGFEGGQMPLYRRLPKFGFTSMKSAVTAEVRLNELTKVEGNVVTLETLKAANILTKDIQFAKVILAGEVKSAVTVRGLRVTKGAKAAIEAAGGSIEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: PPNP_ECO7I
Sequence: MLQSNEYFSGKVKSIGFSSSSTGRASVGVMVEGEYTFSTAEPEEMTVISGALNVLLPDATDWQVYEAGSVFNVPGHSEFHLQVAEPTSYLCRYL
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: NUDL_ECOLC
Sequence: MEYRSLTLDDFLSRFQLLRPQINRETLNHRQAAVLIPIVRRPQPGLLLTQRSIHLRKHAGQVAFPGGAVDDTDASAIAAALREAEEEVAIPPSAVEVIGVLPPVDSVTGYQVTPVVGIIPPDLPYRASEDEVSAVFEMPLAQALHLGRYHPLDIYRRGDSHRVWLSWYEQYFVWGMTAGIIRELALQIGVKP
What is the function of this protein?
Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.
What are the official names of this protein?
Uncharacterized Nudix hydrolase NudL.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. PCD1 subfamily.
Protein: C1D_CHICK
Sequence: MAEDINAEEYPTEIHDYLTTFEKSLTSVDEMLKTMMSVSRSELLQKLEPLEQAKLDLVSAYTLNSMFWVYLATQGINPKEHPVKQELERIRTYMNKVKEIADKKKASKLDKGAASRFVRNALWEPNPENGQTPAKAKKRKMN
What is the function of this protein?
Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5. 8S rRNA.
What are the official names of this protein?
Nuclear nucleic acid-binding protein C1D.
What is the protein family that this protein belongs to?
Belongs to the C1D family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Nucleus, nucleolus.
Protein: GLYA1_SULDN
Sequence: MSFLKEFDKDIFDLCEKELERQSNHLEMIASENFTLPAVMEAMGSVFTNKYAEGYPAKRYYGGCEYADGVEQLAIDRACKLFGCNYANVQPHSGSQANAAVYAALLKAGDKLLGMDLSHGGHLTHGSKPSFSGQNYSSFTYGVELDGRMNYDKILEIAKAVQPKIIVCGASAYAREIDFKKFREIADAVGAIMFADIAHVAGLVVAGEHMSPFPHAHVVTTTTHKTLAGPRGGMIMTNDEDIAKKINSAIFPGIQGGPLVHVIAAKAVGFKYNLSAEWKDYAVQVKANAKILGEVLVKRGYDLVSGGTDNHLVLLSFLNRDFSGKDADIALGNAGITVNKNTVPGETRSPFVTSGIRIGSPALTSRGMKEREFEFIANKIADVLDDINNTKLQESVKKELKELAQKFVIYNQSTY
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase 1, SHMT 1, Serine methylase 1.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KATG1_CELJU
Sequence: MDNNPPTSTGKCPFTHGSVTASGKSNTDWWPNALNLDILHQHDRKTNPLGDDFSYAAAFKTLDLQAVKNDLKALMTDSQDWWPADWGHYGGLFIRMAWHSAGSYRIADGRGGAGTGNQRFAPLNSWPDNGNLDKARRLLWPIKKKYGNKLSWADLMILAGNMAYESMGLKTFGFGGGREDIWHPEKDVYWGSEKEWLAKSGGEGSRYSGERDLENPLAAVMMGLIYVNPEGVDGNPDPLRTAKDIRETFARMAMNDEETVALTAGGHTVGKAHGNGNAANLGPDPEAADVEEQGLGWVNHKTRGIGRDTVTSGIEGAWTTHPTKWDNGYFDMLLNHDWELTKSPAGAWQWKPVSIKEEDMPVDVEDPSIRCTPLMTDADMAMKMDPEYRKISERFYSDPAYFSEVFARAWFKLTHRDLGPKARYLGADVPAEDLIWQDPVPTVDYTLSDADIADLKAKILASGLSVAELVATAWDSARTFRGSDFRGGANGARIRLAPQKDWEGNEPARLQKVLGVFAGIQSGLSKKVSIADLIVVGGAAAVEKAARDAGVNITVPFAPGRGDATDAQTDAESFAPLEPVHDGFRNWVKKDYAVQPEEMLLDRAQLMGLTAPEMTVLVGGMRVLGANYGGSKNGVFTDKVGVLSNDFFVNLTDMAYQWKPTGKNSYNIVERNTGTVKWSATRVDLVFGSNSILRSYAEVYAQDDNREKFVRDFVKAWVKVMNADRFDLK
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase 1, CP 1, Peroxidase/catalase 1.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: SYA_BARBA
Sequence: MNSVNNIRSTFLDYFHRNGHEVLSSSPLVPRNDPTLMFTNAGMVDFKNVFTGLEKHSYNRATTAQKCVRAGGKHNDLDNVGYTARHHTFFEMLGNFSFSNYFKEEAIFYAWNLLTKEFCLSKDKLLVTVYHDDDVAAGLWRKISGLSEEKIIRIATNDNFWMMGDTGPCGPCSEIFYDHGDKIWGGPPGSADEDGDRFIEIWNLVFMQYEQLSKEKRIELPQPSIDTGMGLERIAAVLQGVHDNYDIDLFRTLIHASQEIIGVKATGDFFASHRVIADHLRSSAFLIADGIMPSNEGRGYVLRRIMRRAMRHAHLLGSKDLLMWRLVPVLISEMGQAYPELVRAESLISEILKLEETRFRKTLERGLGLLNEASTHLEEGDYFNGEVAFKLYDTYGFPLDLTQDALRRRGISVDVDAFDKAMKRQKAEARANWSGSGDCVTETVWFSIRDQVGATEFLGYETEKAEGIITALIRDGEVVDHIDLGQKAMIVVNQTPFYGESGGQVGDSGIISGANFIFEVHDTQKKGDNVFIHIGEIKTGQAKKHDCVELIVDSARRRKIRANHSATHLLHESLRQTLGSHVVQKGSFVSPDRLRFDFSHPKSISSEELKKIEDLANDIVLQNSKVTTRLMAIDDAIAEGAMALFGEKYGDEVRVISMGNNLEQTGSKKWWSIELCGGTHVQRTGDIGLIHIISETSVAAGVRRIEALTATAARLYLHGQDRRVYEIAGLLKTSPADVQERVQTLLDERRKLEKELNDSRKKIALNGGSVNSQGDIQTINGISFMGGVVSNILPKDLKALVDSGKKKIGSGVVAFISVSEDGKGSAVVGVTDDLTDTLNAVDLVRIISVTLGGQGGGGRRDMAQAGGSEGGKADEALVALKDSLKG
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VRK1_DANRE
Sequence: MPPKKADGVKKARAPAKRKLAEEFPSGEVLTDNAKKKWKLGSAVGQGGFGLLYLANEDSSGPVTADAPYVIKVEPSDNGPLFSELKFYMRAAKPDLIGAWMKSKKMEYLGVPKYWGSGFHEKNGKRYRFMVMDRFGTDLQKLFEGNGKKFSRKLVLQLGLRLLDILEYIHDHEYVHADIKASNLLLSYTNPNQVFLVDYGLAYRYAPEGVPKEYKEDPKRCHDGTIEFTSIDAHKGVSPSRRADLEIMGYCMIQWLCSRLPWEDKLQDPLYVRDSKLRCRDNIDEFLKSCFASGNIPAEMGKFMQEVKVLGYTDRPDYDKLRGILQQGLKSIGSTDDKKLDFGVATNSTSLPSVKTPKRKKAEEKGQSADETDSTPAKKRRAPQKKEVNGAKKTASPAKRPVKKETQASSEPAVKKSRGRPKKNS
What is the function of this protein?
Serine/threonine kinase involved in cell cycle, nuclear condensation and transcription regulation.  Involved in Golgi disassembly during the cell cycle: following phosphorylation by PLK3 during mitosis, required to induce Golgi fragmentation.  Phosphorylates p53/TP53 and may thereby prevent the interaction between p53/TP53 and MDM2.  Phosphorylates KAT5 in response to DNA damage, promoting KAT5 association with chromatin and histone acetyltransferase activity.  Phosphorylates BANF1: disrupts its ability to bind DNA, reduces its binding to LEM domain-containing proteins and causes its relocalization from the nucleus to the cytoplasm.  Phosphorylates ATF2 which activates its transcriptional activity.
What are the official names of this protein?
Serine/threonine-protein kinase VRK1, Vaccinia-related kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. VRK subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: SURE_HELPY
Sequence: MKKILLTNDDGYHAKGIKALEQALEEMAEIYVVAPKHEKSACSQCITITAPLRAEKIKGKEGRHYRIDDGTPSDCVYLAINELFKHVCFDLVISGINLGSNMGEDTIYSGTVAGAIEGTIQGVPSIAISQILSNKNKNTPLSFDLAQKIIQDLVQNIFTKGYPLKGRKLLNVNVPNCSLQEYQGERITPKGYRLYKKEVHKRTDPKNESYFWLGLHPLEWQKRENEDRLSDFDAIASNHASITPLNLDLTSYDDLKSLESWHEGMLK
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FADI_COLP3
Sequence: MTIKRLTTSTGERIAIVAGLRTPFAKQATAFHGVPAVDLGKIVVNELLQKHDVDPGIIDQLVFGQVVQMPEAPNIAREIVLGTGMNTRTDAYSVSRACATSFQSTVNVAESIMAGHVDVGIAGGADSSSVAPIGVSKKLARTLVDLTKARSLGQRLSLLSRLGLKDLLPVSPAVAEYSTGISMGQTAEQMAKTYQISRQDQDALAHRSHTLATKSWQEGKLAGEVMTVHAEPYKSFIDRDNCFRENSVLESYAKLKPVFDRKHGTVTAATSTPLTDGGAAILLMREGRAKELGYKPLGYIRSFGFAAIDVWQDMLMGPSYATPIALQRAGMNLADLDLIEMHEAFAAQALANMKMFGSTKFAQEQLGRDKAIGDIDMDKFNVMGGSLAYGHPFAATGARLITQTLNELNRRGGGVGLTTACAAGGLGAAMIVETD
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, ACSs, Acetyl-CoA acyltransferase, Acyl-CoA ligase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ORF2_TTVT1
Sequence: MSDEGYRELVESKSAPTTPGPWSPDRERWKRHEAAWKQHCSWSHGLWCHCHDWTRHLKKETRECGSGTESGEDPAVSFDLVDDAAMLAAAGDAEPGAAGGG
What are the official names of this protein?
Uncharacterized ORF2 protein.
Protein: TYRA_STAAR
Sequence: MTTVLFVGLGLIGGSLASNIKYHNPNTNIIAYDADTSQLDKAKSIGIINEKCLNYSEAIKKADVIIYATPVAITNKYLSELIHMPTKPGVIVSDTGSTKAMIQQHECSLLKHNIHLVSGHPMAGSHKSGVLNAKKHLFENAYYILVYNEPRNEQAANTLKELLSPTLAKFIVTTAEEHDYVTSVVSHLPHIVASSLVHVSQKNSQEHHLVNKLAAGGFRDITRIASSNAQMWKDITLSNKTYILEMIRQLKSQFQDLERLIESNDSEKLLSFFAEAKSYRDALPAKQLGGLNTAYDLYVDIPDESGMISKVTYILSLHNISISNLRILEVREDIYGALKISFKNPTDRERGMQALSDFDCYIQ
What are the official names of this protein?
Prephenate dehydrogenase, PDH.
What is the protein family that this protein belongs to?
Belongs to the prephenate/arogenate dehydrogenase family.
Protein: SYK_THESQ
Sequence: MLKEFKEQRLNEIQELRSMGIEPYPYKFEKELTAREIREKYDYLQAGEVLESEKLSFAGRVMSIRHHGKTAFFHMKDDTGRIQAYVRADSVGKEKMDLFKRHVKIGDFIGVRGFPFKSKTGELTIYVQEYTLLSKALRPLPEKWHGIKDKEIIYRQRYLELIVSDEAIERFRKRFKAVQVIREFLNSRGFIEVETPILHYVTGGAEARPFVTHLNVFDIDMYLRIAPELYLKRLIIGGFEKIYEIGKNFRNEGISYKHSPEFTSIEIYQAYADYNDMMDLTEELIVEVVKRTCGTLKISYQGKEIDFTPPWKRVRMRDFLKEKLGVDILEDPDEVLLKKLEEYGVELEIKNRAHLIDKLRDLVEEELVNPTFIIDHPVVISPLAKRHREDPRLTERFELIIFGREIANAFSELNDPVDQYQRFLEQAKMREEGDEEAHMMDLDFVRALEYGMPPTGGLGIGLDRLFMFITDSPTIRDVIPFPIVKPKKFEEEEAEFEGGFEE
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_ACIAC
Sequence: MARKTPIERYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAATTCFWKGMDMSYPEHRFNIIDTPGHVDFTIEVERSMRVLDGACMVYCAVGGVQPQSETVWRQANKYKVPRLAFVNKMDRTGANFFKVYDQMRLRLKANPVPVVIPIGAEEGFKGVVDLLKMKAIIWDEASQGMKFNYEEIPADLAESAKEWREKMVEAAAEASEELMNKYLEEGDLSEEEIKLGLRTRTIATEIQPMLCGTAFKNKGVQRMLDAVIDYLPSPVDIPPVAGTDEDEAETTRKADDNEKFSALAFKLMTDPFVGQLTFVRVYSGVLSKGDSVYNPVKGKKERIGRIVQMHANERLEVEEIRAGDIAACVGLKDVTTGETLCDPEAIVTLERMVFPEPVIAQAVEPKTKTDQEKMGIALQRLAAEDPSFRVKTDEESGQTIISGMGELHLEIIVDRMKREFGVEANVGKPQVAYRETIRKTVEEAEGKFVRQSGGKGQYGHVVLKIEPNEAGKGIEFVDAIKGGVVPREFIPAVEKGINEAVTQGVLAGYPVVDVKVTLHFGSYHDVDSNELAFKMAAIFGFKEGCKKAGPVILEPMMAVEVETPEDYAGTVMGDLSSRRGMVQGMDDMVGGGKAIKAEVPLSEMFGYSTALRSATQGRATYTMEFKHYSEAPRNVSEAIMAARAK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROK_ECO7I
Sequence: MAEKRNIFLVGPMGAGKSTIGRQLAQQLNMEFYDSDQEIEKRTGADVGWVFDLEGEEGFRDREEKVINELTEKQGIVLATGGGSVKSRETRNRLSARGVVVYLETTIEKQLARTQRDKKRPLLHVETPPREVLEALANERNPLYEEIADVTIRTDDQSAKVVANQIIHMLESN
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase 1, SK 1.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYDP_KLEP7
Sequence: MDHQTAEALRAFTQRYCAVWQQQRHSLPRSEELYGVPSPCVVDTQGEAVFWQPQPFSLAQNISAVERALDIVVQQPLHSYYTTQFAGDMSGRFAGETLTLLQTWSEEDFQRVQENLIGHLVVQKRLKLSPTLFIATLESELDVISVCNLSGEVVKETLGTAKRITLSPSLAGFLNHLEPVL
What is the function of this protein?
Interacts with the SecY protein in vivo.  May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.
What are the official names of this protein?
Protein Syd.
What is the protein family that this protein belongs to?
Belongs to the Syd family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Loosely associated with the cytoplasmic side of the inner membrane, probably via SecY.