PharMolix/UniProtQA huggingface dataset:
Protein: ARGB_ANADF
Sequence: MKTIVLKLGGELVHAPELDVIARDLRVLVDGFNRVAIVHGGGPQASALQKTLGLETRMVAGRRYTDAQTLEVMKYVVAGQLNVDLCGRLLANGVMGVGLHGASGHVVQARRRPPRVMKGAGPEPVDLGLVGDVLGFNLPLLGDLFERRYVPVIACLGCDAQGQALNINGDTVASQLAGALEADALVLVTSTPGVLRDVNDPSSRIPHITHAEFERMVADGTISGGMIPKLEESFAVLDSGAKSVVIVGKLGEGDLAHAVLNPGSAGTVLVG
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRC_PECAS
Sequence: MSESFDASAFLKTVTSQPGVYRMYDAGNTVIYVGKAKDLKKRLASYFRSHVASRKTEALVKSIKHIDVTITHTETEALLLEHNYIKLYQPRYNVLLRDDKSYPMIFLSGDAHPRLTVHRGAKHAKGEYFGPFPNGNAVRETLILLQKLFPVRQCENSVYRNRSRPCLQYQIGRCLGPCVSGLVSEEDYRQQVEYVRLFLSGKDQQVLNQLISRMESASRDLRFEDAARIRDQIQAVRRVTEKQFVSGDGEDLDVISVAFDAGMACVYVLFIRQGKVLGSRSYFPKVPGGTELGEVVQTFVGQFYLQGNSGRTLPTEILLDFTLPDKDLLTESLTAVAGRKVQIQTKPRGDRARYLKLARTNAATALVTKLSQQSTIHQRLAALANVLQLPEIHRMECFDISHTMGEQTVASCVVFDANGPLRSEYRRYNISGITPGDDYAAMAQVLQRRYGKALDDSKIPDVIVIDGGKGQLGQAQAVFDSLQVSWDKNKPLLLGVAKGSDRKAGLETLFLEATGEGMALPADSPALHVIQHIRDDSHDHAIGGHRKKRAKVKNTSTLELIEGVGPKRRQTLLKYMGGLQPLMNASIEEIANVPGISHGLAEKIFHALKH
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPIN_DROME
Sequence: MSLKHQKQSYQPLPTAAAMDNPAMIQSSGSSGSSSSEEGGSREDVANLSPLGLPTTYSSQQLMPSDTDSMEEERHRLRPHHHHHHPLGEHHHIPGIPPSAVVPSRLSSVGRSQWFTVTVLCFVNLINYMDRFTIAGVLTDVRNDFDIGNDSAGLLQTVFVISYMVCAPIFGYLGDRYSRPWIMAVGVGLWSTTTLLGSFMKQFGWFIAFRALVGIGEASYSTIAPTIISDLFVHDMRSKMLALFYFAIPVGSGLGYIVGSKTAHLANDWRWALRVTPILGIVAVFLILLIKDPVRGHSEGSHNLEATTYKQDIKALVRNRSFMLSTAGFTCVAFVAGALAWWGPSFIYLGMKMQPGNENIVQDDVAFNFGVITMLAGLLGVPLGSFLSQYLVKRYPTADPVICAFGLLVSAPLLTGACLLVNSNSVGTYALIFFGQLALNLNWAIVADILLYVVVPTRRSTAEAFQILISHALGDAGSPYLVGAISEAIMKHLHKNPSDSGLTTELRSMSQVAGSAISNATQVIAEATTSLMETARSSASQEYSDVEQFEGLQYALFSTSFVEVLGGIFFIFTACFIIKDKYNATRGLQDATAQQQQRDERGQIA
What is the function of this protein?
Probable sphingolipid transporter that plays a central role in endosomes and/or lysosomes storage.  Involved in TGF-beta-mediated synaptic growth regulation both pre- and postsynaptically via its function in endosomal storage regulation.  Also required during oogenesis by regulating yolk spheres storage.
What are the official names of this protein?
Protein spinster, Protein benchwarmer, Protein diphthong.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
What are the subcellular locations of this protein?
Late endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein.
Protein: Y209_DINSH
Sequence: MTDTAPTPEKMPQKIVLVTGPSGAGRTTAIRALEDLGFEAIDNMPISLVPRLLDGPPLARPLALGLDARTRDFSVTAVADLLHLLAEDPRADAQLLFLDASPRVLTRRFSETRRRHPLAPLESPMDGIARETDLLAPIRARADVVIDTSELSPHDLRAEMLRWFGDRDSLRLAITVQSFSYKRGVPQGTDMVFDVRFLRNPYWEDTLRRLDGRDARVQDYVSADPRFDSFFDNIASLVRLLLPAYREEGKSHLSIGFGCTGGQHRSVTVAEKLSAALVAEGWQVSNRHLELSRRSIGAQS
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Dshi_0209.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: H31_USTMA
Sequence: MARTKQTARKSTGGKAPRKQLATKAARKSAPAAGGVKKPHRYKPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAIGALQEAAEAYLVSLFEDTNLAAIHAKRVTIQPKDIALARRLRGERS
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.1.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: NHLF_RHORH
Sequence: MTSTTITPHHIGGAWTRTERRRLASVVGAIVILHVLGVALYLGYSGNPAAAGGLAGSGVLAYVLGVRHAFDADHIAAIDDTTRLMLLRGRRPVGVGFFFAMGHSTVVVVLALVVALGASALTTTELEGVQEIGGLVATVVAVTFLSIVAGLNSVVLRNLLCLSRQVRAGSDITGDLESRLSERGLFTRLLGNRWRGLVRSSWHMYPVGLLMGLGLETASEVTLLTLTASAATGGTLSIAAVLSLPLLFAAGMSTFDTADSLFMTRAYSWSYQDPQRRLNFNIATTGATVVIGLFVAGIYVCALLAHLPMFAALSPIGDISENFEFLGYAVAAAFILTWTGALLFNHLKPQRN
What is the function of this protein?
Mediates energy-dependent uptake of cobalt ions into the cell.  Can also transport nickel ions, but cobalt is the preferred substrate.
What are the official names of this protein?
Cobalt transport protein NhlF.
What is the protein family that this protein belongs to?
Belongs to the NiCoT transporter (TC 2.A.52) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KPSC5_ECOLX
Sequence: MIGIYSPGIWRIPHLEKFLAQPCQKLSLLRPVPQEVDAIAVWGHRPSAAKPVAIAKAAGKPVIRLEDGFVRSLDLGVNGEPPLSLVVDDYCIYYDASKPSALEKLVQDKAGNTALISQAREAMHTIVTGDLSKYNLAPAFVADESERSDIVLVVDQTFNDMSVTYGNAGPHEFAAMLEAAMAENPQAEIWVKVHPDVLEGKKTGYFAALRATQRVRLIAENVSPQSLLRHVSRVYVVTSQYGFEALLAGKPVTCFGQPWYAGWGLTDDRHPQSALLSARRGSATLEELFAAAYLRYCRYIDPQTGEVSNLFTVLQWLQLQRRHLQQRNGYLWAPGLTLWKSAILKPFLQTATNRLSFSRRCTAASACVVWGVKGEQQWRAEAQRKSLPLWRMEDGFLRSSGLGSDLLPPLSLVLDKRGIYYDATRPSDLEVLLNHSQLTLAQQMRAEKLRQRLVESKLSKYNLGADFSLPAEAKDKKIILVPGQVEDDASIKTGTVSIKSNLELLRTVRERNPHAYIIYKPHPDVLVGNRKGNIPTELIAELADYQALDADIIQCIQRADEVHTMTSLSGFEALLHGKQVHCYGLPFYAGWGLTVDEHHCPRREQKLTIADLIYQTLIVYPTYIHPTLLQPISVEEAAEYLIQTPRKPMFITRKKAGRVIRYYRKLIMFCKVRFG
What are the official names of this protein?
Capsule polysaccharide export protein KpsC.
What is the protein family that this protein belongs to?
To R.meliloti lipopolysaccharide processing protein LpsZ.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MLTD_ECOL6
Sequence: MKAKAILLASVLLVGCQSTGNVQQHAQSLSAAGQGEAAKFTSQARWMDDGTSIAPDGDLWAFIGDELKMGIPENDRIREQKQKYLRNKSYLHDVTLRAEPYMYWIAGQVKKRNMPMELVLLPIVESAFDPHATSGANAAGIWQIIPSTGRNYGLKQTRNYDARRDVVASTTAALNMMQRLNKMFDGDWLLTVAAYNSGEGRVMKAIKTNKARGKSTDFWSLPLPQETKQYVPKMLALSDILKNSKRYGVRLPTTDESRALARVHLSSPVEMAKVADMAGISVSKLKTFNAGVKGSTLGASGPQYVMVPKKHADQLRESLASGEIAAVQSTLVADNTPLNSRVYTVRSGDTLSSIASRLGVSTKDLQQWNKLRGSKLKPGQSLTIGAGSSAQRLANNSDSITYRVRKGDSLSSIAKRHGVNIKDVMRWNSDTANLQPGDKLTLFVKNNNMPDS
What is the function of this protein?
Murein-degrading enzyme.  May play a role in recycling of muropeptides during cell elongation and/or cell division (By similarity).
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase D, Murein hydrolase D, Regulatory protein DniR.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: ACCA_ECOUT
Sequence: MSLNFLDFEQPIAELEAKIDSLTAVSRQDEKLDINIDEEVHRLREKSVELTRKIFADLGAWQIAQLARHPQRPYTLDYVRLAFDEFDELAGDRAYADDKAIVGGIARLDGRPVMIIGHQKGRETKEKIRRNFGMPAPEGYRKALRLMQMAERFKMPIITFIDTPGAYPGVGAEERGQSEAIARNLREMSRLGVPVVCTVIGEGGSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKSADKAPLAAEAMGIIAPRLKELKLIDSIIPEPLGGAHRNPEAMAASLKAQLLTDLADLDVLSTEDLKNRRYQRLMSYGYA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPPH_ECOSM
Sequence: MIDDDGYRPNVGIVICNRQGQVMWARRFGQHSWQFPQGGINPGESAEQAMYRELFEEVGLSRKDVRILASTRNWLRYKLPKRLVRWDTKPVCIGQKQKWFLLQLVSGDAEINMQTSSTPEFDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFASVVMSLQENTPKPQNASAYRRKRG
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: A1IA7_LOXHI
Sequence: WIMGHMVNAIYQTDEFVNLGANSIETDVSFDDNANPEYTYHGIPCDCGRSCLKWENYNDFLKGLRSATTPGNSKYQSKLILVVFDLKTGSLYDNQASEAGKKLAKNLLKHYWNNGNNGGRAYIVLSIPDLNHYPLIKGFTDTLKQEGHPELLEKVGYDFSGNDAVGDVAKAYKKAGVSGHVWQSDGITNCLLRGLTRVKEAVANRDSGNGYINKVYYWTVDKRATTRDALDAGVDGVMTNYPDVIADVMNEAAYKNKVRLATYEDSPWVTFKK
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LhSicTox-alphaIA2avii, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ZEB1_RAT
Sequence: MADGPRCKRRKQANPRRNNVTNYNTVVEANSDSDDEDKLHIVEEESVTDAADCEGGVPDDELPTDQTVLPGGSDRAGSAKNCWQDDVKDDECDSDAENEQNHDPNVEEFLQQQDTAVIYPEAPEEDQRQGTPEASGHDDNGTPDAFSQLLTCPYCDRGYKRFTSLKEHIKYRHEKNEDNFSCSLCSYTFAYRTQLERHMTSHKSGREQRHVTQSGGNRKFKCTECGKAFKYKHHLKEHLRIHSGEKPYECPNCKKRFSHSGSYSSHISSKKCISLMPVNGRPRSGLKTSQCSSPSLSTSPGSPTRPQIRQKIENKPLQEPLSVNQIKTEPVDYEFKPIVVASGINCSTPLQNGVFSGGGQLQATSSPQGVVQAVVLPTVGLVSPISINLSDIQNVLKVAVDGNIIRQVLENNQASLASKEQEAVSASSIQQGGHSVISAISLPLVDQDGTTKIIINYSLEQPGQLQVVPQNLKKENPAPPKSCKSEKSPEDLTVKSEKDKSFDGAADESTCLLCEDCPGDLNALPELKHYDPEHPAQPPPPAPATEKPESSASSAGNGDLSPSQPPLKNLLSLLKAYYALNAQPSTEELTKIADSVNLPLDVVKKWFEKMQAGQIPGQSLEPPSPGPGSGNIPAKTEEQPQPVDGNEPQEDSTRGQSPLKMTSSPVLPVGSAINGSRSCTSSPSPLNLSSARNPQGYSCVSEGTQEEPQVEPLDLSLPKQQGELLERSTVSSVYQNSVYSVQEEPLNLSCAKKEPQKDSCVTDSEPVVNVVPPSANPINIAIPTVTAQLPTIVAIADQNSVPCLRALAANKQTILIPQVAYTYSATVSPAMQEPPVKVIQPNGNQDERQDTSSEGVSVEDQNDSDCTPPKKKTRKAENGMYACDLCDKIFQKSSSLLRHKYEHTGKRPHECGICRKAFKHKHHLIEHMRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRYSYCKRGAEDRDAMEQEDTGPEALPEVLPTELVGARASPSQADSDERESLTREEDEDSEKEEEEEDKEMEELQEDKECENPQEEEEEEEEEEEEEEEEEEEEAEEAEHEAAAAKTGGAVEEEAAQQAGSFQQKASGSESKRLSEEKTNEA
What is the function of this protein?
Acts as a transcriptional repressor.  Binds to E-box sequences in the immunoglobulin heavy chain enhancer as well as in the regulatory regions of many other tissue-specific genes.  Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1.  Represses BCL6 transcription in the presence of the corepressor CTBP1.  Positively regulates neuronal differentiation.  Represses RCOR1 transcription activation during neurogenesis.  Represses transcription by binding to the E box (5'-CANNTG-3').  Promotes tumorigenicity by repressing stemness-inhibiting microRNAs (By similarity).
What are the official names of this protein?
Zinc finger E-box-binding homeobox 1, Transcription factor 8, TCF-8, Zinc finger homeodomain enhancer-binding protein, Zfhep.
What is the protein family that this protein belongs to?
Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYB_VORPE
Sequence: MTNIRKTHPLTKIINNSFIDLPAPSNISAWWNFGSLLGICLILQILTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWIIRYTHANGASMFFICLFLHVGRGLYYGSYMFPETWNIGIILLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTSLVEWIWGGFSVDKATLTRFFAFHFILPFIILALAAIHLLFLHETGSNNPSGIPSNSDKIPFHPYYTIKDILGALFLIITLMTLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSILVLAIIPLLHTSKQRSMMFRPLSQCLFWLLVADLLTLTWIGGQPVEYPFIIIGQLASILYFMILLIFMPIISIAENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RIMK1_SHESW
Sequence: MKIGILSQFPQLYSTQRLVAACESRGHEAVVINTLNCYMNINSIKPSIHYEGQELVGFDAIIPRIHASVTFYGCAVVRQFEMMGVFVANDSISIARSRDKLRALQLLSRKGIGMPITGFANKPNDIPDLINMVGGAPLVIKLLEGTQGIGVVLAETKTAAESVIEAFLGLKANILVQEYIKESNGSDIRCFVVGDKVVASMKRQGPEGDFRSNLHLGGCGETVKITSVERKMAIAAVKAMGLVVAGVDILRSNRGPLILEVNSAPGIEGIEQTTGISVTEPIVEYIEKMVAARKTNRPIIA
What are the official names of this protein?
Probable alpha-L-glutamate ligase 1.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: QUEF_GLUOX
Sequence: MSDHHPTGPSAPGTDALSQLGRATTTPQSPEEAVLERVPSPHQGRQYVVRFTAPEFTSLCPVTGQPDFAHIVIDYIPGEWIVESKSLKLFLTSFRNHGAFHEDCSIAIAERLVALLDPQWLRIGAYWYPRGGIPIDVFWQTGEPPKGVWIPAQDVPGYRGRG
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_CLOP1
Sequence: MQDKLNQIKELALVEIKEAKDSTTIDTIRVKYLGKKGELTTILRGMGSLSKEERPIVGKLANEVREVLEAELEAVTKAVKEAEKQEKLKNEVIDISMPGKKQTIGKKHPLEQTLDEMKKIFVSMGFAIEDGPEVEKDYYNFEALNIPKNHPARSEQDTFYINDNVVLRTQTSPVQARVMEKQQPPIKMISPGKVFRSDAVDATHSPIFYQMEGLVIDKDITFADLKGTLELFAKKMFGDKVKTKFRPHHFPFTEPSAEMDATCFVCNGKGCKVCKGEGWIEILGCGMVHPQVLRNCGIDPEVYSGFAFGFGVDRMVMLKYGIDDIRLLYESDMRFLNQF
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTN_HELPY
Sequence: MLSKDIIKLLNEQVNKEMNSSNLYMSMSSWCYTHSLDGAGLFLFDHAAEEYEHAKKLIVFLNENNVPVQLTSISAPEHKFEGLTQIFQKAYEHEQHISESINNIVDHAIKGKDHATFNFLQWYVSEQHEEEVLFKDILDKIELIGNENHGLYLADQYVKGIAKSRKS
What is the function of this protein?
Iron-storage protein.
What are the official names of this protein?
Bacterial non-heme ferritin.
What is the protein family that this protein belongs to?
Belongs to the ferritin family. Prokaryotic subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BRNP3_HUMAN
Sequence: MIWRSRAGAELFSLMALWEWIALSLHCWVLAVAAVSDQHATSPFDWLLSDKGPFHRSQEYTDFVDRSRQGFSTRYKIYREFGRWKVNNLAVERRNFLGSPLPLAPEFFRNIRLLGRRPTLQQITENLIKKYGTHFLLSATLGGEESLTIFVDKRKLSKRAEGSDSTTNSSSVTLETLHQLAASYFIDRDSTLRRLHHIQIASTAIKVTETRTGPLGCSNYDNLDSVSSVLVQSPENKIQLQGLQVLLPDYLQERFVQAALSYIACNSEGEFICKENDCWCHCGPKFPECNCPSMDIQAMEENLLRITETWKAYNSDFEESDEFKLFMKRLPMNYFLNTSTIMHLWTMDSNFQRRYEQLENSMKQLFLKAQKIVHKLFSLSKRCHKQPLISLPRQRTSTYWLTRIQSFLYCNENGLLGSFSEETHSCTCPNDQVVCTAFLPCTVGDASACLTCAPDNRTRCGTCNTGYMLSQGLCKPEVAESTDHYIGFETDLQDLEMKYLLQKTDRRIEVHAIFISNDMRLNSWFDPSWRKRMLLTLKSNKYKSSLVHMILGLSLQICLTKNSTLEPVLAVYVNPFGGSHSESWFMPVNENSFPDWERTKLDLPLQCYNWTLTLGNKWKTFFETVHIYLRSRIKSNGPNGNESIYYEPLEFIDPSRNLGYMKINNIQVFGYSMHFDPEAIRDLILQLDYPYTQGSQDSALLQLLEIRDRVNKLSPPGQRRLDLFSCLLRHRLKLSTSEVVRIQSALQAFNAKLPNTMDYDTTKLCS
What is the function of this protein?
Inhibits neuronal cell proliferation by negative regulation of the cell cycle transition.  Promotes pituitary gonadotrope cell proliferation, migration and invasion, when overexpressed.  May play a role in cell pituitary tumor development.
What are the official names of this protein?
BMP/retinoic acid-inducible neural-specific protein 3, DBCCR1-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the BRINP family.
What are the subcellular locations of this protein?
Secreted. Mitochondrion.
Protein: RMLA_XANCP
Sequence: MTQRKGIILAGGSGTRLYPITKGVSKQLLPVYDKPMIYYPLSVLMLAGIRDILIINTPHEQALFQSLLGDGAQWGVNIQYAVQPSPDGLAQAYLIGRDFVGGKPSCLVLGDNIFHGHGLTDTLRRADAREQGATVFGYWVNDPERYGVAEFDQHGKVIDIAEKPEKPRSNYAVTGLYFYDGKASDYAAALKPSPRGELEITDLNRCYLDAGDLHLEPLGRGYAWLDTGTHQSLHEAANFIETIQMRQGLQVCCPEEIAFGQGWIDAEQLERLAAPLLKNDYGKYLTALAKRGAVH
What is the function of this protein?
Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.
What are the official names of this protein?
Glucose-1-phosphate thymidylyltransferase, dTDP-glucose pyrophosphorylase, dTDP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the glucose-1-phosphate thymidylyltransferase family.
Protein: RSMA_ECO45
Sequence: MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEIGPGLAALTEPVGERLDQLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTFNFGELAAKMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRLSVMAQYYCNVIPVLEVPPSAFTPPPKVDSAVVRLVPHATMPHPVKDVRVLSRITTEAFNQRRKTIRNSLGNLFSVEVLTGMGIDPAMRAENISVAQYCQMANYLAENAPLQES
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCH9_CANAL
Sequence: MVDFAKSLFGFGNYKKESSSQSPTPPPSAHSSQEQHHKSNTEEYPQSHLSQQQHSHRYQPPHMSEQSHQFPQQQQQQQQSGTNKFFPKTLVSAAPTTAVANHSSVYGTTSTTTNNYPEAYLNQTFKNNIYNPQQQQQQQAQQPPPEQQQSSAPYQNSANIQQPYGNQWGSSQDQDANIITIDKTGNKLSPASRDSPIKGKLKVTILEAKDIFATQPYVVCSFESSEFVTNAPDSYGKSPVSSFGHNNNQGHNGPRNMYNSNHGPSPKALPMKNSGNLFGQRPSMYQRQLSTPHLNLPNDSSNPIWNHDTIFDVVGSKSELDISVYDGARDDAFLGHVRISPSTDKNNKNESEWLQLGARITGETVSSGHIKIKWEYTSFDNNIKRSYGPDDFHFLRLLGKGTFGQVFQVRKKDTNRVYAMKILSKKVIVKKKEIAHTIGERNILVRTSAASSPFIVGLKFSFQTPSDLFLVTDFMSGGELFFHLQKEGRFNEDRSKFYTAELILALEHLHDNDIVYRDLKPENILLDANGHIALCDFGLSKADLNMDGTTNTFCGTTEYLAPEVLLDEQGYTKMVDFWSLGVLIFEMTCGWSPFHAENTQQMYKNIAFGKVRFPKDVLSPEGRSFVKGLLNRNPKHRLGATDDARELKAHPFFADIDWDLLRAKNIPPPFKPHIVSETDISNFDTEFTSENTSALKRQMEMATTPLSPGIQANFKGFTYVDDSTMDDHFARSYRANAFRPPGSFIPGDPNLPPDEEVLAEQIEEEDEMEVDEDQHMDDEFVNGRFDL
What is the function of this protein?
Protein kinase that is part of growth control pathway which is at least partially redundant with the cAMP pathway (By similarity).  Plays a role in filamentous growth and virulence.  Prevents hypha formation specifically under hypoxia at high CO(2) levels.  Required for chlamydospore formation, distinctive morphological feature of the fungal pathogen C. albicans that can be induced to form in oxygen-limited environments and has been reported in clinical specimens.
What are the official names of this protein?
Serine/threonine-protein kinase SCH9.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.
Protein: MALF_VIBCH
Sequence: MQSVQGTQAMSDPTAVRPADKRAFLKWAVLGAVGIVNGYATILMYSRGEVAFALLTLILTTLALYIFGSRKTYAHRYIYPGIAGMILFILFPLAYTVGLAFTNYSAKNQLTLERAQSVLMDQTFQSGESYAFQLYKTEQGYRLLIEDGDERLATAPFSLSGNVPTDLNLEVIGGIDGEVEPIKTIIGYRTELSGIDLHFPDGEDIRMSGLRKFAAVKPLYTLQDDGETLTNNQSGQVLRPNMEIGFYQPINESGEFVGERVSPGFVVSIGTHNFERVWKDEGIKEPFINIFIWTVIFSVLTVIFTLMIGLVLASVVQWEALKGRAVYRVLLILPYAVPAFISILIFRGLFNQSFGEINMVLNGLFGLSPAWFSDPLLAKTMVLIVNTWLGFPYMMIFCMGLLKAIPDDLYEASAIDGANFIHNFTKITLPMMIKPLTPLLIASFAFNFNNFVMIQLLTQGGPNRIGTSEPAGYTDLLVSYTYRIAFEGTGGQDFGLASAIATLIFLLVGALALLNLRFTKLSQQ
What is the function of this protein?
Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Maltose/maltodextrin transport system permease protein MalF.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PGLR_ASPFU
Sequence: MLKLMGSLVLLASAAEVIASPAAEPVAPSTTLEKRAPCTFSGSNGAAAAMASQKACSTIVLSNVAVPAGTTLDLSDLADGTTVTFEGETTWGYQEWSGPLLKISGKNIKVKGASGATLNPDGARWWDGQGGNGGKTKPKFFAAHDLTSSSSITDLHILNTPVQAVSINGCDGLTITDITIDNSAGDTQGGHNTDAFDIGSSSNIIISGAKVYNQDDCVAVNSGTDITFTGGLCSGGHGLSIGSVGGRSDNTVENVSFTNSQVTNSDNGLRIKATKGKTGTIKGVTYSGITLSSIRKYGILIEQNYDGGDLKGDPTSGIPITDLTMQNISGKGAVASSGYNIAIVCGSGACSNWTWKSVEVTGGKTYGSCKNVPSVAQC
What is the function of this protein?
Involved in maceration and soft-rotting of plant tissue.  Hydrolyzes the 1,4-alpha glycosidic bonds of de-esterified pectate in the smooth region of the plant cell wall (By similarity).
What are the official names of this protein?
Probable endopolygalacturonase AFUA_1G17220, Pectinase AFUA_1G17220, Polygalacturonase AFUA_1G17220.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted.