PharMolix/UniProtQA huggingface dataset:
Protein: GTR11_HUMAN
Sequence: MRALRRLIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNFPRRAQGPTWRSLEVIQSTEL
What is the function of this protein?
Facilitative glucose transporter.
What are the official names of this protein?
Solute carrier family 2, facilitated glucose transporter member 11, Glucose transporter type 11, GLUT-11.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y408_MYCPN
Sequence: MVIKKGFFALSSCTLGLGLILTACGARGKFDQVDDGVIKLATSIQNKDSIAALNTIYKKYKERHPGSYPVQNFQVPGGYSGLRNDIRTRLSAKDGNNFYNIVLNYPDVVSSLATSDMQLILDNVDTKLLSKNFLSFNERIGGVRQKGIYAIPISLSTELMVLNGPVLHYILNSAKKKENGAQMIKRSGSFSTVQKGTMAIDMNDQKTKDLWQKIENAAKANGKTTSTQTSPQPKNAVSSLQLKQAAEGTSTDNSQDAENSDNEIKKTWGEYKEEGNHTLKGYTFKASVFENWNELLDFSTRVANSFPDKIKNQASKKATELQGVFGVDSVSGALFSATFAAGGGDYDKFFFNVKNGRGNFRNLLEKGSSYNNLQKVFNDYKQLISSNGLYINKGGAYSSNFLKFHQLAFSVGSSSGYHFAFAGESAKRLEFGQKAIEYPRDTYEIKAPTNSQNGNGTLLGSFTKSKSNGKEQSGQDEDNQTSETIELYKSSVPSGKEAGKNALAITNQQLISALENAAKDNKTSQPQARSLTASDQVQITQSSDKVIGYITTSNLDIDNNNTFDVGKLNGDKSTSKIIVNATLKTLNKINTLQSEEGIILPHPQKYKSTDPQAVATVQGPSIIGVHANAKENAETQKFINWFINQKETWPENSKGNKNGQNGQMTAAQYFAKSSGYVLPYSETFTKQSEDEHSTTKDAYKILKDVNDGKLVGYSDPSDFRSGKFRDTIVAAFSGAVSSKADFNKFFKGFEQQLGQEYRRG
What are the official names of this protein?
Uncharacterized lipoprotein MPN_408.
What is the protein family that this protein belongs to?
Belongs to the MG185/MG260 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: DNAK_GLAP5
Sequence: MGKIIGIDLGTTNSCVAVMDGDKPRVIENAEGARTTPSIIAYTDKETLVGQPAKRQAITNPKNTLFAIKRLIGRRFTDSEVQRDIEIMPFEITKADNGDAWVSVKGEKMAPPQISAEVLKKMKKTAEDFLGEPVTEAVITVPAYFSDAQRQATKDAGRIAGLEVKRIINEPTAAALAYGLDSKKENQIVAVYDLGGGTFDLSIIEIDNLDGEQTFEVRATNGDTHLGGEDFDNRLINYLVEEFQKEQGVDLRNDSMAMQRVKEAAEKAKIELSSAQSTEVNLPYITADATGPKHLVLTVTRAKLEALVEDLVNRSLEPVKVALADAGLSVSEINDVILVGGQTRMPLVQKKVADFFGKEPRKDVNPDEAVAIGAAVQGGVLAGDVTDVLLLDVTPLSLGIETMGGVMTTLIEKNTTIPTKKSQVFSTAEDNQSAVTIHVLQGERKRASDNKSLGQFNLEGINPAPRGMPQIEVTFDIDANGIINVSAKDKNTGKEQQIKIQASSGLSDAEIEQMVRDAEANAEADRKFEELVQTRNQADAIAHSTRKQIAEAGSNLADADKAKIEEAVAALEKAAKGEDKADIEAKIEALVKASEPLIQAGQAQAQQGQQQAQQSQKDDGVVDAEFEEVKDNK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: CMOA2_YERPS
Sequence: MPNRDTQSQNDTPRHSPEAAEPQRDSLFAAPIAKLGDWTFDEKVAEVFPDMIQRSVPGYSNIISMIGMLAERFVQPNSQIYDLGCSLGAATLSMRRNIKAEGCKIIAVDNSPAMVERCRRHIDAFRAETPVDVVEADILDIKLENASMVVLNFTLQFLEPANRQRLLNQVYQGLRPGGALVLSEKFSFADHNVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVETHKNRLHQAGFEHAEVWFQCFNFGSLIALKAGEAQ
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase 2, Cx-SAM synthase 2.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: AT1B3_RAT
Sequence: MTKTEKKSFHQSLAEWKLFIYNPTSGEFLGRTSKSWGLILLFYLVFYGFLAALFTFTMWVMLQTLNDEVPKYRDQIPSPGLMVFPKPPTALDYTYSMSDPHTYKKFVEDLKNFLKPYSVEEQKNLTDCPGGALFHQEGPDYSACQFPVSLLQECSGVNDSNFGYSKGQPCVLVKMNRIIELVPDGAPYITCITKEENIANIVTYPDDGLIDLKYFPYYGKKRHVGYRQPLVAVQVIFGADATKKEVTIECQIDGTRNLKNKNERDKFLGRVSFKVIAHA
What is the function of this protein?
This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.  The exact function of the beta-3 subunit is not known.
What are the official names of this protein?
Sodium/potassium-transporting ATPase subunit beta-3, Sodium/potassium-dependent ATPase subunit beta-3, ATPB-3.
What is the protein family that this protein belongs to?
Belongs to the X(+)/potassium ATPases subunit beta family.
What are the subcellular locations of this protein?
Apical cell membrane; Single-pass type II membrane protein. Basolateral cell membrane; Single-pass type II membrane protein. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Protein: KPTA_BURPS
Sequence: MSSSYFIATRASKFLSYVLRHRPDSIGVTLDAQGWADVSELLTKAAAAGMALTLDELKQVVAENDKKRFVLNDDATRIRAAQGHSVDVDLQLPVKAPPPVLYHGTVGKSMADIRKQGLTPMNRHDVHLSPDRETATRVATRRGKPVILVIETYPLLRDGYQFRVSDNGVWLVPEVPAKYIKFPG
What is the function of this protein?
Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P).  May function as an ADP-ribosylase.
What are the official names of this protein?
Probable RNA 2'-phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the KptA/TPT1 family.
Protein: NSP4_ROTYO
Sequence: MDKLADLNYTLSVITLMNDTLHSIIQDPGMAYFPYIASVLTVLFTLHKASIPTMKIALKTSKCSYKVIKHCIVTIINTLLKLAGYKEQVTNKDEIEQQMDRIVKEMRRQLEMIDKLTTREIEQVELLKSIHDNLTTKPVDVIDMSKEFNQKNIKTLDEWVSGKNPYEPSEVTASM
What is the function of this protein?
The secreted form acts as an enterotoxin that causes phospholipase C-dependent elevation of the intracellular calcium concentration in host intestinal mucosa cells.  Increased concentration of intracellular calcium disrupts the cytoskeleton and the tight junctions, raising the paracellular permeability.  Potentiates chloride ion secretion through a calcium ion-dependent signaling pathway, inducing age-dependent diarrhea.  To perform this enterotoxigenic role in vivo, NSP4 is released from infected enterocytes in a soluble form capable of diffusing within the intestinal lumen and interacting with host plasma membrane receptors on neighboring epithelial cells such as integrins ITGA1/ITGB1 and ITGA2/ITGB1.
What are the official names of this protein?
Non-structural glycoprotein 4, NSP4, NCVP5, NS28.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP4 family.
What are the subcellular locations of this protein?
Host rough endoplasmic reticulum membrane; Single-pass type III membrane protein. Host membrane, host caveola; Single-pass type III membrane protein. Secreted. Note=NSP4 localizes also in vesicular structures which contain autophagosomal markers and associate with viroplasms in virus- infected cells. Additionally, a soluble form of glycosylated NSP4 is secreted despite retention of its transmembrane domain.
Protein: GCH1_SHEB9
Sequence: MALSEAAVKVQAALLERGLETPMLPSVYSSEERKDKIEHHMKEILTLMSLDLSDDSLADTPRRIAKMYVDEIFSGLDYANFPKITVIDNKMGFDEMVRVQDISLTSTCEHHLVTIDGTATIAYLPRKKIIGLSKINRIVRFFAQRPQVQERLTQQVLVALQTLLETKDVAVKMDAVHYCVKSRGVMDSTSSTTTTALGGIFKSNPATRAEFLHQSK
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: CH601_MYCA1
Sequence: MSKIIEYDETARRAIEAGVNTLADAVRVTLGPRGRHVVLAKAFGGPAVTNDGVTVAREIDLEDPFENLGAQLVKSVATKTNDVAGDGTTTATVLAQALVKGGLRLVAAGANPIELGAGISKAADAVSEALLASATTVSGKDAIAQVATVSSRDQVLGELVGEAMTKVGVDGVVSVEESSTLNTELEFTEGVGFDKGFLSAYFVTDFDAQQAVLDDPVILLHQEKISSLPDLLPMLEKVAESGKPLLIIAEDIEGEALATLVVNSIRKTLKAVAVKAPFFGDRRKAFLEDLAIVTGGQVINPDTGLLLREVGTEVLGSARRVVVSKDDTIIVDGGGAKDAVANRIKQLRAEIEKTDSDWDREKLQERLAKLAGGVAVIKVGAATETALKERKESVEDAVAAAKAAVEEGIVAGGGSALLQARKALDELRGSLSGDQALGVDVFAEALGAPLYWIASNAGLDGAVAVHKVAELPAGHGLNAEKLSYGDLIADGVIDPVKVTRSAVLNSASVARMVLTTETAVVDKPAEEADDHGHGHHHH
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 1, 60 kDa chaperonin 1, Chaperonin-60 1, Cpn60 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EDN3_PIG
Sequence: MELRLWFLFGLTVTSAAGPVPRPQPGDAGRSGVPRAPSATKETMAMVATRGPSPRSSGQEQEPGPFGELAAKGGPVRYRARRCTCFTYKDKECVYYCHLDIIWINTPERTVPYGLSNHRGSVRGRRSAGPSPQSSQPSRGTLRCACAESQDRACVYFCTRTLAARGASRTPETPDKEAGKPAGRATGGLHPRRLKSRTDKARRL
What is the function of this protein?
Endothelins are endothelium-derived vasoconstrictor peptides.
What are the official names of this protein?
Endothelin-3, ET-3, Preproendothelin-3, PPET3.
What is the protein family that this protein belongs to?
Belongs to the endothelin/sarafotoxin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TMCA_PECAS
Sequence: MRDFLHSQQQQQRYGIRRLLVLSGESSWCEEQAMVLSSQSAGDWLWVSEHAPDSVASLPASRVRTLLGREFHHAVFDARSGVDVEALAMLSGTLRAGSWLIMLVPSWQVWSTLPDEDSLRWSEHAQPIATPHFIQHFQRQLLADDDVVLWQQGQPLVIQPLAVRSDWQPAQGEPTARQQQILHELSAAESGVFVITAPRGRGKSTLAGMLTQRSRGTCWITAPSRSATDILQQYARSDAPFWAPDALLAYCRLHGAPDVDWLLIDEVAAIPSSVLTALLPYFPRILMTTTVQGYEGTGRGFLLKFCAALPQCRVFSLDDPLRWAANDPLERVLDQALLFNEPASLHFPLNPTDGALTLPSAKLDIRTECADDWLTHPERLTWCYALLCSAHYRTSPLDLRRLMDAPGMHIASAQVAGDIRGVLWLVEEGGLSDSLAHDVWAGRRRPRGNLVAQSLAAHAGLWNAPTLRARRVSRIAVASSSRRQGIGRALIADQTREAQKQALDYLSVSFGYQPDLWAFWQSCGFQLVRIGSHLEASSGCYSAMAILPLSEAGYELAQQGSQQLARDWYWLQRMIPLNLALPQTENIERDTESIALNDDDWRELAGFAFAHRPMEASFAAICRLLIHTSLPLPALRLLAETPSEGEQTAATLGLTGKKALLKRWREETTSALIELDAQRGERWRLWVLPDDAAEDALHP
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
What are the official names of this protein?
tRNA(Met) cytidine acetyltransferase TmcA.
What is the protein family that this protein belongs to?
Belongs to the RNA cytidine acetyltransferase family. TmcA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VM3VB_CROAT
Sequence: MIQVLLVTICLAAFPYQGSSIILESGNVNDYEVIYPRKVTALPKGAVQPKYEDAMQYELKVNGEPVVLHLGKNKGLFSKDYSETHYSPDGREITTYPLVEDHCYYHGRIENDADSTASISACNGLKGHFKLQGEMYLIEPLKLPDSEAHAVYKYENVEKEDEALKMCGVTQNWESYEPIKKASQLVVTAEHQKYNPFRFVELFLVVDKAMVTKNNGDLDKIKTRMYEIVNTVNEIYRYMYIHVALVGLEIWSNEDKITVKPEAGYTLNAFGEWRKTDLLTRKKHDNAQLLTAIDLDRVIGLAYVGSMCHPKRSTGIIQDYSEINLVVAVIMAHEMGHNLGINHDSGYCSCGDYACIMRPEISPEPSTFFSNCSYFECWDFIMNHNPECILNEPLGTDIISPPVCGNELLEVGEECDCGTPENCQNECCDAATCKLKSGSQCGHGDCCEQCKFSKSGTECRASMSECDPAEHCTGQSSECPADVFHKNGQPCLDNYGYCYNGNCPIMYHQCYDLFGADVYEAEDSCFERNQKGNYYGYCRKENGNKIPCAPEDVKCGRLYCKDNSPGQNNPCKMFYSNEDEHKGMVLPGTKCADGKVCSNGHCVDVATAY
What is the function of this protein?
Disintegrin catrocollastatin-C: Abolishes platelet aggregation induced by collagen (IC(50)=66 nM) but not ADP-stimulated platelet aggregation.  This inhibition may be due to its ability to bind collagen and block the binding site on collagen for platelets and/or to its ability to bind to the platelet alpha-2/beta-1 collagen receptor (ITGA2/ITGB1) to block its interaction with collagen and hence prevent platelet stimulation.
What are the official names of this protein?
Zinc metalloproteinase-disintegrin-like VAP2B, Catrocollastatin, Snake venom metalloproteinase, SVMP, Vascular apoptosis-inducing protein 2B, VAP2B.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-III subfamily. P-IIIb sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NEP_I72A4
Sequence: MDSNTVSSFQDILLRMSKMQLGSSSEDLNGMITQFESLKLYRDSLGEAVMRMGDLHLLQNRNGKWREQLGQKFEEIRWLIEEVRHRLKTTENSFEQITFMQALQLLFEVEQEIRTFSFQLI
What is the function of this protein?
Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs).  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell.  Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain.  This domain is believed to allow recognition of RNPs bound to the protein M1.  Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized.  Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane.  May down-regulate viral RNA synthesis when overproduced.
What are the official names of this protein?
Nuclear export protein, NEP, Non-structural protein 2, NS2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses NEP family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: EFTS_PORGI
Sequence: MAVTIQDIAKLRKMSGAGMMDCKNALEESNNDFEKAMEIIRKKGQAVAAKRSDREAAEGCVLSADKDGFAAIVALKCETDFVAKNAEFIELTQNILNTAMDKKPANKEELLALPLADGRTIADHITDRIGVTGEKMELGAYEYISGASSISYIHPGNKLATVAAFNEAIEHQMARDIAMQIAAMNPVAVLPEQVDQHIIDQELQIAREKALEAGKPENLLDRIAQGALQKYYKENTLLQQEFVKDSKLTIEQYLHTGSKTLTVVGFKRFTLNAD
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENTC_ECOLI
Sequence: MDTSLAEEVQQTMATLAPNRFFFMSPYRSFTTSGCFARFDEPAVNGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEKQASARRFTRSQSLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDAAIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWHLATPFEGKANSQENALTLACLLHPTPALSGFPHQAATQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGLH
What is the function of this protein?
Involved in the biosynthesis of the siderophore enterobactin (macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine).  Catalyzes the reversible conversion of chorismate to isochorismate.
What are the official names of this protein?
Isochorismate synthase EntC, Isochorismate mutase.
What is the protein family that this protein belongs to?
Belongs to the isochorismate synthase family.
Protein: MIC10_HUMAN
Sequence: MSESELGRKWDRCLADAVVKIGTGFGLGIVFSLTFFKRRMWPLAFGSGMGLGMAYSNCQHDFQAPYLLHGKYVKEQEQ
What is the function of this protein?
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
What are the official names of this protein?
MICOS complex subunit MIC10, Mitochondrial inner membrane organizing system protein 1.
What is the protein family that this protein belongs to?
Belongs to the MICOS complex subunit Mic10 family.
Protein: GRPE_THEMA
Sequence: MSEKEKKELTQECEELKEKYKELEEYAKRLKAEYENYREEVAREKRELIKNANEYLISKLIPVLDDFERALNQGEKGDAFYEGVKMIYKKLLNVLEKEGLTKIHVGEKFDPFEHEAVERVETEDVEEYTILEVVESGYKFHGKVLKPAKVKVAVKPRKKEERKVEEPSDKKE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHOP_ECOLI
Sequence: MRVLVVEDNALLRHHLKVQIQDAGHQVDDAEDAKEADYYLNEHIPDIAIVDLGLPDEDGLSLIRRWRSNDVSLPILVLTARESWQDKVEVLSAGADDYVTKPFHIEEVMARMQALMRRNSGLASQVISLPPFQVDLSRRELSINDEVIKLTAFEYTIMETLIRNNGKVVSKDSLMLQLYPDAELRESHTIDVLMGRLRKKIQAQYPQEVITTVRGQGYLFELR
What is the function of this protein?
Member of the two-component regulatory system PhoP/PhoQ involved in adaptation to low Mg(2+) environments and the control of acid resistance genes.  In low periplasmic Mg(2+), PhoQ phosphorylates PhoP, resulting in the expression of PhoP-activated genes (PAG) and repression of PhoP-repressed genes (PRG).  In high periplasmic Mg(2+), PhoQ dephosphorylates phospho-PhoP, resulting in the repression of PAG and may lead to expression of some PRG (By similarity).  Mediates magnesium influx to the cytosol by activation of MgtA.  Promotes expression of the two-component regulatory system rstA/rstB and transcription of the hemL, mgrB, nagA, slyB, vboR and yrbL genes.
What are the official names of this protein?
Transcriptional regulatory protein PhoP.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIC_COXBU
Sequence: MRREGTMRLHRTFLLRVYLKESAVITYPASKKIYCQGKIFPTIRVGMREIQLTNGDSLTLYDTSGPYSDPNISIKSPQGLPRLREPWIKVRPRKTQLAFAKEGVITPEMEYAAIRENQKRELKKNTDQERERRLQGNSLSARIPNPITPEFIRNEIACGRAILPANINHPESEPMIIGRHFLVKVNANIGNSSLTSSVEEEVEKLIWALRWGADTVMDLSTGKKIKEIRETILRHSPVPIGTVPLYEALEKVDGDVKALTWEIFRDTLISQAEQGVDYFTIHAGVLNRFIPLTQKRVTGIVSRGGSLMAKWCLLHREENFLYTHFTEICEIMRAYDVSFSLGDGLRPGSIADANDEAQFAELKIQGELNRIAWKYGVQVMNEGPGHIPLNLIEENMTKQLAYCREAPFYTLGPLTTDIAPGYDHIGSAIGAAFIAWQGCALLCYVTPKEHLGLPNKQDVKEGLIAYKIAAHAADLAKGHPAARQRDYLLSQARFEFRWHDQFNLALDAETARLFHDETLPKEAAKHAHFCSLCGPKFCAYKTSHEVRDTLQKVT
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: BCHL_HELMO
Sequence: MIIAVYGKGGVGKSTTTSNLAVAIAKEGKRVLQIGCDPKSDSTFTIAGKMIPTVVEILDKFNYHYESIEPGDLIFTGYGGVDVVETGGPPAGSGCGGYVVGETVKLLEKMDVMARYDVILFDVLGDVVCGGFATPLQYADLACVVSSNDFDALFAANRICESVVEKNMSGYDVKMAGVIGNRCDQVDLLETFTRRIETPLMGVVPRKEEIRQSRVKGYTLFELEEMGEPVQDMTAEFRKMARYLLSKPDGVIPNAVGTREMFELFKGEDMPWKGSNGKTGASTPSAQ
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
What are the official names of this protein?
Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein, DPOR subunit L, LI-POR subunit L.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: NU4C_SACHY
Sequence: MSYFPWLTILVVLPIFAGSLIFFLPHKGNKIVRWYTIAICLLEFLIMTYAFCYHFQLEDPLIQLKEDSKWIDVFDFHWRLGIDGLSLGSILLTGFITTLATLAAWPVTRNSQLFYFLMLAMYSGQIGLFSSRDLLLFFIMWELELIPVYLLLSMWGGKRRLYSATKFILYTAGGSIFFLIGVLGMGLYGSNEPGLDLERLINQSYPTTLEILLYFGFLIAYAVKLPIIPLHTWLPDTHGEAHYSTCMLLAGILLKMGAYGLIRVNMELLPHAHYLFSPWLVIIGAVQIIYAALTSLGQRNFKKRIAYSSVSHMGFIIIGIGSITNIGLNGAILQILSHGFIGATLFFLAGTACDRMRLVYLEELGGISIPMPKIFTMFSSFSMASLALPGMSGFVAELVVFFGLITSPKFMLMPKMLITFVMAIGMILTPIYLLSMLRQMFYGYKLFHVPNKNFVDSGPRELFLLICIFLPVIGIGIYPDFVLSLSVDRVEVLLSNYYTK
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase chain 4, chloroplastic, NAD(P)H dehydrogenase, chain 4, NADH-plastoquinone oxidoreductase chain 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: LPXA_SALSV
Sequence: MIDKSAFIHPTAIVEDGAVIGANVHIGPFCIVGPQVEIGEGTVLKSHVVVNGQTKIGRDNEIYQFASIGEVNQDLKYAGEPTRVEIGDRNRIRESVTIHRGTVQGGGLTKVGSDNLLMINAHVAHDCTVGNRCILANNATLAGHVSVDDFAIIGGMTAVHQFCIIGAHVMVGGCSGVAQDVPPYVIAQGNHATPFGVNIEGLKRRGFSREGLVAIRNAYKLLYRSGKTLDEAKLEIAELAEKHPEVKAFTEFFERSTRGPIR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS81_BURMA
Sequence: MTTPEDIIRRDVLAMTGYPVPDATGFVKLDAMENPYSLPAPLAAELGERLAHVALNRYPAPRPAALIDRLRAVTGVPAACDVLLGNGSDEIISMLAMACAKPGAKVLAPVPGFVMYELSAKFAQLEFVGVPLRADLTLDIDAMLAALAEHRPALVYLAYPNNPTGTLYPDEDVERIIAAAAASLVVIDEAYQPFAQRSWLPRAAQFDNVVVMRTMSKLGLAGIRLGYLVGLPAWLVQFDKVRPPYNVNVLTQAAAEFLLERVDVLDAQAAQLRDARTALAHAIGALPGATVFPSAGNFLLVRVPDAAAVFDVLLTERVLIKNVSKMHPLLANCVRVTVGSPEENARLLAALKLALP
What are the official names of this protein?
Histidinol-phosphate aminotransferase 1, Imidazole acetol-phosphate transaminase 1.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: Y095_ARCFU
Sequence: MERWDPLTWHCIISSYYFYIFWNFFLPMFIVYRGFGLLDPFAVKGRYTSDCYIFLLSEEPFENVTHCSSQRQSWALWSSHQRISRLQRLTTEHHKANRGQATIRKTLA
What are the official names of this protein?
Uncharacterized protein AF_0095.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL28_RUMCH
Sequence: MAKCEVCSKATSFGNSRSHALNATSRTWKPNVRKIKIIDNGTPRSIKICTRCLRSNKVTRAI
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: RBPMS_HUMAN
Sequence: MNNGGKAEKENTPSEANLQEEEVRTLFVSGLPLDIKPRELYLLFRPFKGYEGSLIKLTSKQPVGFVSFDSRSEAEAAKNALNGIRFDPEIPQTLRLEFAKANTKMAKNKLVGTPNPSTPLPNTVPQFIAREPYELTVPALYPSSPEVWAPYPLYPAELAPALPPPAFTYPASLHAQMRWLPPSEATSQGWKSRQFC
What is the function of this protein?
Acts as a coactivator of transcriptional activity.  Required to increase TGFB1/Smad-mediated transactivation.  Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity.  Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1.  Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins (PubMed:26347403).  Binds to poly(A) RNA (PubMed:17099224, PubMed:26347403).
What are the official names of this protein?
RNA-binding protein with multiple splicing, RBP-MS, Heart and RRM expressed sequence, Hermes.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, P-body. Note=Translocates into cytoplasmic stress granules that probably correspond to P-bodies in response to oxidative stress.