PharMolix/UniProtQA huggingface dataset:
Protein: LGT_STAA2
Sequence: MGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYAENPSEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGPVSRAFLEQLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTKKVK
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YR259_MIMIV
Sequence: MSEISNIINEPIGDRMKRFEAKYDFKIEPQNYFCVRLDGNKFSNFTRKFEKPYDVRFSQAMVMTTIDTINKFGARTGFTQSDEITLIFDKAIPDDFKKHITYNHLFNGRVSKLLSIVSSYVSVRFNHHFRLLTSNLTNIYSQETLELINGGTAIFDARILEFDENNKYEMLNHLIWRSVKDCYRNAVQTYAHHIFGPAKIKYLNREQMIQLIEENTNIVWSNIPLWQKYGVIIKKQLIKTDNVKNSVITSSFKVFSLKLSYNDTMLKFLFDKYFELDKISEYQLEDYPLSII
What are the official names of this protein?
Uncharacterized protein R259.
Protein: YBEY_KARMG
Sequence: MINYYYETKFHLYNEFYFSKWIFFVVSKENKFIKELNFIFCDDQYLININNKYLNKNYYTDVITFDNSEDKNLDGDIFISIKRIKYNSLKFKKLFYDELKRVIIHAVLHLIGYKDKKETEKYIMSKKEDIYLFFLKKKYVC
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
Protein: RCF1_NEUCR
Sequence: MPNSTDNQGSAPPGLSSRPLPSSFDDNADFYNENGFQKVSRRLREEPLIPIGCIATVAAFTGAYRAMRRGDHEQVQRMFRARVAAQAFTVVAMVAGSWYYAADRQKQKELWKLKEQQDAEEKRQKWIRELEVRDAEDKALQERLEKRRKKKAERDSAAGAPDGVAAQAQAAYADAKEKVSSPAGDVAPEDPNKSNITGVRERLPTWLGGSKGADGSSRDKN
What is the function of this protein?
Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes.
What are the official names of this protein?
Respiratory supercomplex factor 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RCF1 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: YKC3_YEAST
Sequence: MNKEELLGFLLDDSIDSQKRCVTDQQAYSNWLKNDNDERTAHEESSSQSTIAALNKKKQTEAAQEDIEELLNGLEGIIGGADPRNLKSKSKRKTKKGGSKPREENVNTEKHIVMLEVEDFSDMSTHEDVNGASPSPNLDRSKKNEKRRKNAKELSYDELKDKLEVTTRKSRLECKDLKKKVHGLERRNLELEQRLEELKIENQTLIEINNKLLKNTNEDEINKSQRNKEKDRKRRERRTARRKDERKQEKKQEKKQDNKTSQSFPSSTDMNGQPIEF
What are the official names of this protein?
Uncharacterized protein YKL023W.
Protein: HPRK_BURMS
Sequence: MDTSSINAQSIFDDNAAMLKLSWLTGHEGWERGFSADTVANATSSADLVGHLNLIHPNRIQVLGEAEIDYYQRQTDEDRSRHMAELIALEPPFLVVAGGAAAPPELVLRCTRSSTPLFTTPMSAAAVIDSLRLYMSRILAPRATLHGVFLDILGMGVLLTGDSGLGKSELGLELISRGHGLVADDAVDFVRLGPDFVEGRCPPLLQNLLEVRGLGLLDIKTIFGETAVRRKMKLKLIVQLVRRPDGEFQRLPLESQTVDVLGLPISKVTIQVAAGRNLAVLVEAAVRNTILQLRGIDTLRDFMDRQRLAMQDPDSQFPGKLV
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: ERPA_NITMU
Sequence: MNTPFNDGSGQTDPMTDIPTPLIFTDNAANKVRELIEEEGNNDLKLRVFVAGGGCSGFKYGFTFDELISEDDTVMEKNGVKLLVDAMSFQYLAGAEIDYQENAEGAQFIIKNPGAASTCGCGSSFSV
What is the function of this protein?
Required for insertion of 4Fe-4S clusters.
What are the official names of this protein?
Putative iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: NNF1_YEAST
Sequence: MVNSHGIRYIRLKQVFNRALDQSISKLQSWDKVSSCFPQYVNSKQGAINVANCQRQLTEFWTELCQREFKEIMEERNVEQKLNELDELILEAKERYTDRDQDEVNKGPAIDELSSKELVECHLYSQRMHAIHEIDERLAKVNEMNDQLAQELKDLETQVEVEKNEIGKMYDEYLGSHTDQPANVLLVQSLNDMVLELKENY
What is the function of this protein?
Acts as essential component of the kinetochore MIND complex, which is required for the spindle checkpoint and kinetochore integrity.  MIND plays a role in establishing a bipolar spindle-kinetochore interaction by joining kinetochore subunits contacting DNA to those contacting microtubules.  NNF1 is required for a number of nuclear functions.  Cells depleted of NNF11 or containing a temperature-sensitive NNF1 mutation have elongated microtubules and become bi- and multinucleate.  They also have a fragmented nucleolus and accumulate poly(A)+ RNA inside the nucleus.
What are the official names of this protein?
Kinetochore-associated protein NNF1.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with the kinetochore (PubMed:12455957, PubMed:14657030).
Protein: PGK_LEUMM
Sequence: MAKLTVSDLELSGKKVLMRVDFNVPIKAGVIGNDNRIVAALPTIKYVLENNGRAILFSHLGRIKSEDDKKELSLAPVAARLGELLGKDVKFVPQTRGEELESAINALQDGEVLMVENTRFEDVVDGEVVKNESKNNPELGKYWASLGDDLFINDAFGTAHRAHASNVGIASNVSQAAAGFLMEKEIKFLGDAVANPVRPFVAIIGGAKVSDKIEIVKSLLNKADKVIVGGGMAYTFDAAKGNKIGNSLFEADKVELAKELMAEAGDKLVLPIDSIAADAFSNDAKTEVVDAEDGIPDGYMGLDIGPKSVKLLQDTLSDAKTVVWNGPMGVFEMSNFAKGTLAIGEELVKVTENGGTTIVGGGDSTAAVQQLGVADKLTHISTGGGASLEYLEGKELPGIASISEK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P12L1_HUMAN
Sequence: MDSLWGPGAGSHPFGVHNSRLSPDLCPGKIVLRALKESGAGMPEQDKDPRVQENPGDQRRVPEVTGDAPSAFRPLRDNGGLSPFVPGPGPLQTDLHAQRSEIRYNQTSQTSWTSSCTNRNAISSSYSSTGGLPGLKRRRGPASSHCQLTLSSSKTVSEDRPQAVSSGHTQCEKVAEIAPGQTLALRNDSSRSEASRPSTRKFPLLPRRRGEPLMLPPPVELGYRVTAEDLDWEKEAAFQCIKSALQVEDKAISDCRPSRPSHTLSSLATGASGLPAVSKAPSMDAQQERHKSQDCLGLVAPLASATEVPSTAPMSGEKHRPPGPLFSSSDPLPATSSHSQDSAQVTSLIPAPFPAASMDAGMRRTRPGTSAPAAAAAAPPPSTLNRTLGSLLEWMEALHISGPQPQLQQVPRGQNQRSQTSRTSSCPK
What are the official names of this protein?
Putative POM121-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the POM121 family.
Protein: GLYA_STRPG
Sequence: MIFDKGNVEDFDKELWDAIHAEEERQEHHIELIASENMVSKAVMAAQGSVLTNKYAEGYPGNRYYGGTECVDIVETLAIERAKKLFGAAFANVQAHSGSQANAAAYMALIEAGDTVLGMDLAAGGHLTHGSPVNFSGKTYHFVGYSVDADTEMLNYEAILEQAKAVQPKLIVAGASAYSRSIDFEKFRAIADHVGAYLMVDMAHIAGLVAAGVHPSPVPYAHIVTSTTHKTLRGPRGGLILTNDEALAKKINSAIFPGLQGGPLEHVIAAKAVAFKEALDPAFKDYAQAIIDNTAAMAAVFAQDDRFRLISGGTDNHVFLVDVTKVIANGKLAQNLLDEVNITLNKNAIPFETLSPFKTSGIRIGCAAITSRGMGVKESQTIARLIIKALVNHDQETILEEVRQEVRQLTDAFPLYKK
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_LISMC
Sequence: MSIITEVYAREVLDSRGNPTVEVEVYTEAGAFGRALVPSGASTGEYEAVELRDGDKARYLGKGVLKAVENVNDIIADKIIGFDVTDQIGIDKAMIELDGTPNKGKLGANAILGVSLAAARAAADELGVHLYEYLGGVNGKVLPVPMMNILNGGEHADNNVDVQEFMVMPVGAPNFKEALRMGAEILHALKAVLKGKGLNTGVGDEGGFAPNLKSNEEALETIMQAIKDAGYKPGEEVKLAMDAASSEFYNRETGKYELKGEGVTRTSEEMVTWYEEMITKYPIISIEDGLDENDWDGFKLLTERIGDRVQLVGDDLFVTNTTKLKEGIEKGIANSILIKVNQIGTLTETLDAIEMAKRAGYTAVISHRSGETEDSTIADIAVATNAGQIKTGAPTRTDRVAKYNQLLRIEDNLADLAEYHGNETFYNLKK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: Y4G5_ENCCU
Sequence: MRFVGLVNRIFRHSDSMTGRPGQQLASGARARIQGMTSFLSAEEKRKEEEMLRKIKEHGLKLCTKEKQEEMTKAQAGVRCMCTHLGKRGG
What are the official names of this protein?
UPF0329 protein ECU04_1650.
What is the protein family that this protein belongs to?
Belongs to the UPF0329 family.
Protein: CPSC_STRAG
Sequence: MNKIANTEVEINIFNLLKKLWKKKFLITFVAIAFATAGLFYSLFIVTPQYTSSTRIYVINPNTPNNSITAQDLQAGSFLANDYKEIITSTDVLEKVISSEKLNYPSSQLLQKITVSILKDTRVISISVEDANPKMSQKLANSVREAAVSKIKAVTQVEDITTLEKGNLPKAPSSPNIKKNVLIGFIVGAGLSTIVLVIMGILDDRVNTEEDIEKVLGLTSLGIVPDLNKL
What is the function of this protein?
Required for CpsD phosphorylation (By similarity).  Involved in the regulation of capsular polysaccharide biosynthesis.  May be part of a complex that directs the coordinated polymerization and export to the cell surface of the capsular polysaccharide (By similarity).
What are the official names of this protein?
Capsular polysaccharide biosynthesis protein CpsC.
What is the protein family that this protein belongs to?
Belongs to the CpsC/CapA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CAIB_ECO55
Sequence: MDHLPMPKFGPLAGLRVVFSGIEIAGPFAGQMFAEWGAEVIWIENVAWADTIRVQPNYPQLSRRNLHALSLNIFKDEGREAFLKLMETTDIFIEASKGPAFARRGITDEVLWQHNPKLVIAHLSGFGQYGTEEYTNLPAYNTIAQAFSGYLIQNGDVDQPMPAFPYTADYFSGLTATTAALAALHKVRETGKGESIDIAMYEVMLRMGQYFMMDYFNGGEMCPRMSKGKDPYYAGCGLYKCADGYIVMELVGITQIEECFKDIGLAHLLGTPEIPEGTQLIHRIECPYGPLVEEKLDAWLAAHTIAEVKERFAELNIACAKVLTVPELESNPQYVARESITQWQTMDGRTCKGPNIMPKFKNNPGQIWRGMPSHGMDTAAILKNIGYSENDIQELVSKGLAKVED
What is the function of this protein?
Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine.  Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA.
What are the official names of this protein?
L-carnitine CoA-transferase, Crotonobetainyl-CoA:carnitine CoA-transferase.
What is the protein family that this protein belongs to?
Belongs to the CoA-transferase III family. CaiB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3058_YERP3
Sequence: MFGKGGIGNLMKQAQQMQEKMQQMQEEVAKLEVTGESGAGLVKVTINGAHNCRRVEIDPSLLVEDDKEMLEDLIAAALNDAARRIDETQKEKMASVSNGMQLPPGFKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein YpsIP31758_3058.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: YSXE_BACSU
Sequence: MEDTQSVLQEYGLTAQFIEPVSPLVWKVYTDYGIFALKKLKEGRGKHFTDHMVAIEEKGFRSFVPVYRTNSGEFFSAGIQYGDIYYLMPWLQFDQEEERDQKHAYLFRETARLHERTAQELKVRRDEIERYYGQTKKKWEQDKIFYEQFVDRAEKEWYLSPFELQAITYFSETISAVNFALERLEDWYESAKEKDVSRVVMNHGSLSIHHFLYNDAGTGYFTNFERASVGPPQNDLLGFYTKMFRGFPKACPECVEWFYGYTKSFPLREAEVSLFLSYMAYPAAMYKVLNGYQTGKRQHEKEECTQLLKAYWQMKNIEPFVMKIHQIEQEKKFQAENESTS
What are the official names of this protein?
Uncharacterized protein YsxE, ORF2.
Protein: SYV_ORITB
Sequence: MAELSANYNYLENEPKWQDDWQKKNIYQWNSTLPKDKTFIVDPPPPTVSGDLHIGHAMSFIQLDCIVRYQRMLGKNIFFPIGFDDNGLPTERFVEKIKNVRASNIARPDFIKMCQEVVIAKEGEFCKFLNAIGLSVDWSLKYQTISSLSCKISQMSFLDLVNKNQVYRNHQPVLWDCIDQTALSQADVEDKERITSMYYIAFAVMNSELKVQIATTRPEMLPACCAIFFNPNDIRYQHLHNQFAITPLFKSVVPILAEETVDINKGSGLVMCCTFGDTKDVAWWRKHNLPTRIIIDYYGKVKPLDFTVSSQNQEKFTEYYNQITGLKIAQARNKVVELLHHNQLIIKQEQISQTVKQAERSGAILEIIMAPQWFIKVVEHKDALLQKSQELEWYPKSMKIKLDNWINSLAWDWCISRQRYFGIPFPVWYSKREGEEGKIIFADISQLPVDPLYDLPAGYSKDEVIPDSDVMDTWATSSLSPQLSSHGISSNLTIDSTRHNQLFPADLRSQAHEIIRTWTFYTIVKSYLHQNSLPWSKIMISGWCLADDRKKMSKSKGNIILPTELIKRYGADAVRYWALTSQLGHDCVVSEQVIGIGKKLVNKLWNAARFILQHITGKLTAEFLISAKHCVEKKVISCTTDLWMLSKLQDTVNNTSNLLNNYEYASARLYVEEFFLKDFCDNYLELVKSRIYDHSSEYQKSAIYSVFWGLKTILELFAPFVPFITEELYAAIYQSNNLCNGSIHSSNKWPLAQNFYNDELILTTGNLAINILTLVRKSKSARKLSVKAPISLLQVKYDSDSYQQLPSDLVDDLKLVTNSNEFSIVTNFTTIDDLITGDGITVNIVYPGSMKHEC
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_CAUVN
Sequence: MIDLVFPDGSSRQYPDGATGRDVAAAISKSLEKKALLIKLDGQVLDLDRRLTPDLLTGERKFEILTREAPEALDTIRHDTAHVLAEAVQELFPGTQVTIGPNVEDGFYYDFARDEPFSLDDLEKIEKRMKEIVDRDEKITREVWDRNEAIAHFDGIGEQYKAQIIRDLPDTDTITVYRQGNWKDLCRGPHLPSTKHVGKAFKLTKLAGAYWRGDQNNAQLQRIYGTAWASEADLEAHLKRIEEAEKRDHRKLGKTMDLFHIQEEGKGMVFWHPKGWALYRVLEDYMRRRLDAAGYKEVKTPQILDRSLWEKSGHAEKFGHAMFMCESAEGEVLAVKPMNCPGHIQIFNVGQKSYRELPLRMAEFGACHRYEPSGAMHGIMRVRAFTQDDAHIFCREEQVTEESARFIELLRSVYNDLGMTLADTKFSTRPELRAGTDETWDKAEAALAAAAEAAGETLTLQPGEGAFYGPKLEFSLKDAIGRVWQCGTLQLDFVLPERLDAEYVSEDGSKKRPVMLHRAILGSFERFIGILLENFAGALPVWLAPTQVVVATITSDADDYAREVVEKLTKLGMRAELDLRNEKINYKIREHSLAKVPVIAVVGRKEAETGQLALRRLGGEGQSVLSLEEALRVLKSDATPPDVARALAVQEAVTA
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEPX_LIGS1
Sequence: MKFNQFAHVKVPFEQKLAELNRIAFLHAGDEDLASNHIYRLFLERAFPNFKTEAAKNHALSNLAATENADILTYLNSSKINARVFYAVGLQLLGFEAELDFDLKDPFSAMDKLNLPYQKEIHHRDDVINAWYDLLCTSTKKGQNLLDILANRGYFTQFYQLNLTEPIFFNGKAQPVFDTNKLIHEVVYVESELDTDQDGKRDLLKVIITRPAMTDNGMKVPTIFTASPYYLGTNDASAEKMMHSVDLPITRKEVKPLSYQDIEYHKPETKLPKKRPVVISTKNAEESWEHLFTYTFNDYMLARGFAVVYSGGVGTLDSDGYRTCGDEAETLGAKDVVEWLNGKRTAFTTKEANKAIPAWWSNGKVAMTGKSYLGTLATAAATTGVAGLETIISEAAISSWYDYYREGGLVIAPGGFPGEDADILAEECFSRQKSAGDYNHSKDGFNKFLSTITKDQDRTTGNYNTFWDARNYLKDVGNIKCDIVMVHGLNDWNVKLKNVFNLYNKLGDVEVTKKLILHQGQHIYINNFQSLDFTDMMNLWLSHKLYGVENNAKELLPDILVQNNTKESTWETYSSWQSKNFTKLYLNSDSLSAQKKENQTLEFSDHLPETTFKHYQTDIANWKEEILASTSPKLETNRLILTSKPLKHETLLKGVAKIKLKIASQLDHGLVSVKLVDYGDAKRLGATPTILERRGLDLGYHWKEDNLVEFKLAKETPFKMITQAHLNLQNRHNDFSTDELEANKFYDVEITTQPMFYHLPKGHKLGLVIYATDMEMTLQGNEENSYRIDTTGSYCLLPIEE
What is the function of this protein?
Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
What are the official names of this protein?
Xaa-Pro dipeptidyl-peptidase, X-Pro dipeptidyl-peptidase, X-prolyl-dipeptidyl aminopeptidase, X-PDAP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GMT2_YEAS1
Sequence: MIYTSSKSLQYLAVPIYTIFKNLTIILIAYGEVLFFGGKVTSMELTSFIMMVLSSVVATWGDQQAIAIKASSLEDLDQELVESTIFVLNPGYLWMFTNCISSALFVLIMRKRIRLTNFKDYDTMFYNNVLALPLLLVFSFIMEDWSTKNLSVNLSADSLAAMVISGLMSVGISYCSGWCVRVTSSTTYSMVGALNKLPIALAGLVFFDAPKNFLSFFSIFLGFLSGLLYAVAKQKKIQQQKVLAATLEK
What is the function of this protein?
Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.
What are the official names of this protein?
Probable GDP-mannose transporter 2, GMT 2.
What is the protein family that this protein belongs to?
Belongs to the TPT transporter family. SLC35D subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Recycles between the Golgi apparatus and the endoplasmic reticulum.
Protein: UXUA_HAEIN
Sequence: MEQAWRWYGPKDPVSLSDIRQAGATGIVTALHHIPNGEIWGIEEIKKRKTEIENAGLSWSVVESVPVHEEIKTQTGNYQKWINNYKQTLRNLAQCGIDTVCYNFMPVLDWTRTDLAYELPDGSKALRFDHIAFAAFELHILKRPDAEKTYNQEEQVAARTYYDNMSEQDIAQLTRNIIAGLPGAEEGYTLDEFQTQLDRYKDISSEKFRTHLAYFLNEIVPVAQEIGIKMAIHPDDPPRPILGLPRIVSTIEDMQWFVETQPLPANGFTMCTGSYGVRSDNDLVKMTEQFADRIYFAHLRSTQREGNPLTFHEAAHLEGDVDMFNVVKALLNEEYRRLNQGETRLIPMRPDHGHQILDDLRKKTNPGYSAIGRLKGLAEFRGLEMALKKVYFNK
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.
What are the official names of this protein?
Mannonate dehydratase, D-mannonate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the mannonate dehydratase family.
Protein: RIMM_DEHMC
Sequence: MTQEEYILIGKVLGVWGISGGLKIGVLTDFPERFDAGNELLVGRKLYTISQTNWQKAQVIVHLSGIDDIDTALELKDALVEIPASALKELPEGVYYDFQLIGLEVVDLSGVKIGQIKEILHMPSNDIYVSSYGVKEALIPAIKDVVKEINLKTGKIIIDPIPGLLD
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_BART1
Sequence: MTDLRHYDVIISPVITEKSTMISEYNQVAFNVAPKATKPEIKAAVEALFSVKVKAVNTIVRKGKVKRFKGIVGRQSDVKKAIVTLASGQTIDVSTGL
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: FCG3A_MACFA
Sequence: MWQLLLPTALLLLVSAGMRAEDLPKAVVFLEPQWYRVLEKDRVTLKCQGAYSPEDNSTRWFHNESLISSQTSSYFIAAARVNNSGEYRCQTSLSTLSDPVQLEVHIGWLLLQAPRWVFKEEESIHLRCHSWKNTLLHKVTYLQNGKGRKYFHQNSDFYIPKATLKDSGSYFCRGLIGSKNVSSETVNITITQDLAVSSISSFFPPGYQVSFCLVMVLLFAVDTGLYFSMKKSIPSSTRDWEDHKFKWSKDPQDK
What is the function of this protein?
Receptor for the invariable Fc fragment of immunoglobulin gamma (IgG).  Optimally activated upon binding of clustered antigen-IgG complexes displayed on cell surfaces, triggers lysis of antibody-coated cells, a process known as antibody-dependent cellular cytotoxicity (ADCC).  Does not bind free monomeric IgG, thus avoiding inappropriate effector cell activation in the absence of antigenic trigger (By similarity).  Mediates IgG effector functions on natural killer (NK) cells.  Binds antigen-IgG complexes generated upon infection and triggers NK cell-dependent cytokine production and degranulation to limit viral load and propagation.  Involved in the generation of memory-like adaptive NK cells capable to produce high amounts of IFNG and to efficiently eliminate virus-infected cells via ADCC.  Regulates NK cell survival and proliferation, in particular by preventing NK cell progenitor apoptosis (By similarity).  Fc-binding subunit that associates with CD247 and/or FCER1G adapters to form functional signaling complexes.  Following the engagement of antigen-IgG complexes, triggers phosphorylation of immunoreceptor tyrosine-based activation motif (ITAM)-containing adapters with subsequent activation of phosphatidylinositol 3-kinase signaling and sustained elevation of intracellular calcium that ultimately drive NK cell activation.  The ITAM-dependent signaling coupled to receptor phosphorylation by PKC mediates robust intracellular calcium flux that leads to production of pro-inflammatory cytokines, whereas in the absence of receptor phosphorylation it mainly activates phosphatidylinositol 3-kinase signaling leading to cell degranulation (By similarity).  Costimulates NK cells and trigger lysis of target cells independently of IgG binding (By similarity).  Mediates the antitumor activities of therapeutic antibodies.  Upon ligation on monocytes triggers TNFA-dependent ADCC of IgG-coated tumor cells (By similarity).  Mediates enhanced ADCC in response to afucosylated IgGs (By similarity).
What are the official names of this protein?
Low affinity immunoglobulin gamma Fc region receptor III-A, IgG Fc receptor III-A, Fc-gamma RIII-alpha, Fc-gamma RIII, Fc-gamma RIIIa, FcgammaRIIIa.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Secreted. Note=Exists also as a soluble receptor.
Protein: COQ7_BURCM
Sequence: MVLDELISEFDRGLRSLTGISRMSRPVPVPAEPTVGELTPAERAHAAGLMRVNHVGEVCAQALYQAQKLTARSASSKAMFEEAAREEEDHLAWTAHRLKELDSRPSLLNPLWYAGALAIGVAAGTLGDKVSLGFMAETERQVESHLDGHLSELPATDTASRAIVEQMRVDEVKHGKAATDAGGIELPLPARMLMRAASKVMTRTAYYL
What is the function of this protein?
Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
What are the official names of this protein?
3-demethoxyubiquinol 3-hydroxylase, DMQ hydroxylase, 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the COQ7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: G6PI_LEPBL
Sequence: MIRLETRFASSFVNSRKFESFLTEAESSRRTLHSFQGKGNEYLGWLNLPKEIKESEIEKIIQVAQRLRDSSEVIVVIGIGGSYLGSRAVLEATLPFFRRSSKGNPEIFFAGHHLESRYLSELMEYLKDRDFSVNVISKSGTTTEPAIAFRLFWELLRKKYGASAASRVVATTDFSKGTLKTFANVEGFETFTIPDNVGGRYSVLTPVGLFPLAAAGIPIRKFILGSQNILKDLHAETDPVRNPATYYSAFRNYFLSEGRHIEILANFNPSLRYISEWWKQLFGESEGKENKGIFPASMDFTTDLHSLGQYVQEGKRILFETVLSPSDVHSNLILRPTPDNLDSLNFLSGNTLGHVNEQARLGTLLAHADGGVPCLELIFPDISPESLGEVMYFFEYSCAISGYSLGVNPFDQPGVDAYKKNMFALLNKVGFEKEGDFLRKRILGN
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.