PharMolix/UniProtQA huggingface dataset:
Protein: MURC_CLOPE
Sequence: MSFDLLKDINKKVHFIGIGGVSMSGLAAVLLNAGYKVSGSDSKESEITNRLKEEGAKIYIGHSKDNLQDVDVVVYTAAIPSDNPEIIKAKEDNLILMDRAEFLGQIMKGHKFNVAVAGTHGKTTTTSMISHVALSADLDPTILVGGDLDIIHGNFRVGNSEYFITEACEYKQSFLRFFPYVGIILNIDADHLDFYKDINHIKDTFKQFVRLIPNDGYIIGNADDEKVMEVLEVAKCNVLTYGINNGDIQARNIEFNEKGCATFDVFRNEEKLLSLSLNVPGMHNVSNSLSAVCLAEIFNINADSIVSGLSSFGGAHKRFEYKGTKNDITVIDDYAHHPVEIKATLSTAKKMNHNRIVCVFQPHTYTRTKTLFNDFVKCFDDCDELVLMDIYAAREKDLGEINSDQLGDAIRAHGVKCTNVHSHEEALEYVNANLSKGDLLLTVGAGDVVKVGELFLK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARP5_YEAST
Sequence: MSSRDASLTPLKAVVIDDPPLRQTPEPFDEQSAYNPQSPIAIDFGSSKLRAGFVNHATPTHIFPNALTKFRDRKLNKNFTFVGNDTLLDQAVRSQSRSPFDGPFVTNWNLTEEILDYTFHHLGVVPDNGIPNPILLTERLATVQSQRTNWYQILFETYNVPGVTFGIDSLFSFYNYNPSGNKTGLVISCGHEDTNVIPVVDGAGILTDAKRINWGGHQAVDYLNDLMALKYPYFPTKMSYLQYETMYKDYCYVSRNYDEDIEKILTLENLDTNDVVVEAPFTEVLQPQKTEEELRIQAEKRKETGKRLQEQARLKRMEKLVQKQEEFEYFSKVRDQLIDEPKKKVLSVLQNAGFDDERDFKKYLHSLEQSLKKAQMVEAEDDSHLDEMNEDKTAQKFDLLDIADEDLNEDQIKEKRKQRFLKASQDARQKAKEEKERVAKEEEEKKLKEQQWRETDLNGWIKDKRLKLNKLIKRRKEKLKLRDEMKDRKSQVSQNRMKNLASLAEDNVKQGAKRNRHQATIDNDPNDTFGANDEDWLIYTDITQNPEAFEEALEYEYKDIVELERLLLEHDPNFTEEDTLEAQYDWRNSILHLFLRGPRPHDSENIHEQHQMHLNVERIRVPEVIFQPTMGGQDQAGICELSETILLKKFGSQPGKLSQTSIDMVNNVLITGGNAKVPGLKERIVKEFTGFLPTGTNITVNMSSDPSLDAWKGMAALARNEEQYRKTVISKKEYEEYGPEYIKEHKLGNTKYFED
What is the function of this protein?
Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex.
What are the official names of this protein?
Actin-related protein 5, Actin-like protein ARP5.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MURC_CHLTE
Sequence: MPPMELGKTKNVHIVGIGGAGMSAIAELLLKSGFAVSGSDLASGEVIDKLRELGAVIHQGHQAENVGASDVVVYSSAVRPESNVEILAAQKLGIPVIKRDEMLGELMRHKSGICVSGTHGKTTTTAMVATMLLEAGQSPTVMIGGVSDYLKGSTVVGEGKSMVIEADEYDRAFLKLTPTIAVLNSLESEHMDTYGTMDNLRDCFAEFANKVPFYGRVICCVDWPEIRRIIPRLNRRYTTFGIEEHADVMASEIEPGDGGSTFTVEAFGERYPGVRLNVPGRHNVLNALAAFSVGLEIGLPPERIIAGLARYSGMRRRFQVKYRGADGVLVIDDYAHHPTEVKATVRAARDGWKEHRIVAVFQPHLYSRTAEFAGEFGWALSRADTVYVAGIYPSREKAEDYPGITGELVAEASRTAGAKNVWFTEEHEALLAALQEEAAPETLFLFMGAGDITHLAARFAAWCTEMRSNADATAS
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEA_RHILW
Sequence: MRVDLFDFDLPDERIALRPAEPRDSARLLVVNPHAESRPHAESVPHAESRPHAESAFSDHRVGDLPSFLRAGDALVFNDTKVIPAQLEGIRHRDGAGGQQVSATLHMRVGPSRWKAFAKPGKRIKEGDRIAFGHSGESCLLGSLDATVEEKGEAGEVTLAFDLSGPALDEAIAAVGHIPLPPYIAAKRPEDERDRADYQTIYAREEGAVAAPTAGLHFTPALFEALDRAGIERHFVTLHVGAGTFLPVKADDTADHKMHLESGTVSAETAARLNAVKARGGRIVCVGTTSLRLIESAAEESGEIRGWSGATGIFITPGYRFKAVDMLMTNFHLPRSTLFMLVSAFSGFETMHAAYKHAISTGYRFYSYGDASLLFRKDK
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VRAC_STAHJ
Sequence: MRYSLKSGANETREFKFHSEDVRIYCSVIGKEYDGTVPPLMCAKLWPKFKMFQIFKGEAIRLVRTNVELFENLESDIQYCAYLTHKKSEKVKQFDRFIFKLEINKNNKTRMIIEQTFISEDGIYGF
What are the official names of this protein?
Protein VraC.
Protein: RPE_MYCPN
Sequence: MLNLVVNREIAFSLLPLLHQFDRKLLEQFFADGLRLIHYDVMDHFVDNTVFQGEHLDELQQIGFQVNVHLMVQALEQILPVYLHHQAVKRISFHVEPFDIPTIKHFIAQIKQAGKQVGLAFKFTTPLVNYERLVQQLDFVTLMSVPPGKGGQAFNSAVFNNLKQAHKYHCSIEIDGGIKLDNIHQIQDDVNFIVMGSGFIKLERWQRQQLLKTNQ
What is the function of this protein?
Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
What are the official names of this protein?
Ribulose-phosphate 3-epimerase.
What is the protein family that this protein belongs to?
Belongs to the ribulose-phosphate 3-epimerase family.
Protein: DCTN6_DANRE
Sequence: MADPSAKQTGQKSVKIAAGAVVCVESDIRGDVTIGARTVVHPKARIIAEAGPIVIGEGNLIEEQALIINSFPENLLPNTDDVEPKPMIIGVNNVFEVGCVCQALKIGDNNVIESKADVGRSVMLTSGCIVGSCCQIHTCEVIPENTVIYGSECLRRVQTERPQPQTLQLDFLMKILPNYHHLKKTVKSSGTPARS
What is the function of this protein?
Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules.
What are the official names of this protein?
Dynactin subunit 6.
What is the protein family that this protein belongs to?
Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Chromosome, centromere, kinetochore.
Protein: MNHF2_STAA8
Sequence: MIQTITHIMIISSLIIFGIALIICLFRLIKGPTTADRVVTFDTTSAVVMSIVGVLSVLMGTVSFLDSIMLIAIISFVSSVSISRFIGGGHVFNGNNKRNL
What are the official names of this protein?
Putative antiporter subunit mnhF2, Mrp complex subunit F2, Putative NADH-ubiquinone oxidoreductase subunit mnhF2.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TZ721_CYRSC
Sequence: MKAILLLAIFSVLTVAICGVSQNYGNVRYNYTELPNGEYCYIPRRRCVTTEQCCKPYDTVNNFAACGMAWPEDKKRKVNECYICDNELTLCTR
What is the function of this protein?
Probable neurotoxin with ion channel impairing activity.
What are the official names of this protein?
U8-theraphotoxin-Hs1a, U8-TRTX-Hs1a, HWTX-XVa1.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 27 (Jztx-72) family. ICK-72 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: BIOD_CLOBM
Sequence: MARGVFITATGTDIGKTYVTALIIKKLREVNINCGYYKAALSGAERIDSKLIAGDANYVYNIANIKGDPNDAVSYIFQQAVSPHLAAKLNNVEISMDKIKKDFSCIKNKYDYITVEGSGGIICPISMGKEKIMLENIVKSLKLPAIVIADAGLGTINNTILTLQYMKKKNIPIKMILLNNYNHENIIHIENKRYLSDNLSIPVYTCCKDSNNLEIPVERLIEFYEEI
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: O13D1_HUMAN
Sequence: MYRFTDFDVSNISIYLNHVLFYTTQQAGDLEHMETRNYSAMTEFFLVGLSQYPELQLFLFLLCLIMYMIILLGNSLLIIITILDSRLHTPMYFFLGNLSFLDICYTSSSIPPMLIIFMSERKSISFIGCALQMVVSLGLGSTECVLLAVMAYDHYVAICNPLRYSIIMNGVLYVQMAAWSWIIGCLTSLLQTVLTMMLPFCGNNVIDHITCEILALLKLVCSDITINVLIMTVTNIVSLVILLLLIFISYVFILSSILRINCAEGRKKAFSTCSAHSIVVILFYGSALFMYMKPKSKNTNTSDEIIGLSYGVVSPMLNPIIYSLRNKEVKEAVKKVLSRHLHLLKM
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 13D1, Olfactory receptor OR9-15.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: URB1_USTMA
Sequence: MALPPVKIASRPASPTPSHHHQQAAAASSSSSSSSSHHPPPRIAARPIAPADRSPERVSQHSRGASVHDADSLPPIRPRGSRPSSPSGHAADRAPSSHHNASSTATVPARSTARSLFRDPRTLHPAGRSQSPIAAFRNRSQSSERSRLGPSRSQPNSPLLQSSSLRHHSDATGVHLPPISSLSKELVSDHPDCFAHRRRTPTTSPRATARLHMGNTFRDSSPAASSGSPATMRHDHLAYRHEHSAEEHAKMQRYSDEHPRAMNPTSRASYEHESRGMPYRDSYSAPSRAIEASYHANGARPVHHADSSTNSPQYVPGDVYEHEGSGSPPAAHHAGMRCSNCGVTSTPLWRRAPDGSTICNACGLYIKSHSTHRSASNRLSGSDASPPTHEAKLAAAGPSCSREDDPKSGSCPGDGLCNGTGGTASCSGCPAYNNNLSHALKVSKRESQTSEDPPPARTAERAPPVAEEKMDDDKSVVGALRCTNCQTTTTPLWRRDEDGNNICNACGLYHKLHGTHRPIGMKKSVIKRRKRIPANATAQPTHILDVIPVQMNANGQPVIAPAAGRNAGDSTPKSTESRRASKKSSLTSEQAMREARDREAAMLLMEVGAGARSRNSAQEDDRIHQNGALATSTSFHHDFHSARAGADTARTSHPDDSRSSKRPRQSYPLAPREAYDERDVSAIASPPAYNETHAAGATRSQRSQRSPVDAPLTDRLGRSELHGESSHGTSNAPEHAARASASDGARLGSVVPHHHHHHHHHHANHASHAVHHGHHHHHHHPVTVSASSHGHAGQAPSGMTKLSEVERLRDELLFERRRIDEVLRRAEAILASARAGNFHVEAAGPSTSGLRNGHEASHESPPTGSAQGSPGADARGTRSGHDSIKQEAPDAAPRRSKAFSNSSSSSEKDELESPPPSAHQQLASQPLVAATGAQPASRRNSFEQRMASLPVMAAVPLKRSSPPSTVSNPADNRPLSIAPQPARKATAWGIDTRSTPAASPRSGEKRARADEMDEDDDHWNWDNLYGKAKLEKAGDWRGFARPVEDRRSQSKSNGVTRRESSSTPIAARLPVASSPSQAVSAPRT
What is the function of this protein?
Involved in the regulation of secreted ferrichrome-type siderophores.  Acts directly or indirectly to repress the biosynthesis of siderophores.
What are the official names of this protein?
Siderophore biosynthesis regulatory protein URBS1.
What are the subcellular locations of this protein?
Nucleus.
Protein: PI4P2_HUMAN
Sequence: MTVEQKFGLFSAEIKEADPLAASEASQPKPCPPEVTPHYIWIDFLVQRFEIAKYCSSDQVEIFSSLLQRSMSLNIGRAKGSMNRHVAAIGPRFKLLTLGLSLLHADVVPNATIRNVLREKIYSTAFDYFSCPPKFPTQGEKRLREDISIMIKFWTAMFSDKKYLTASQLVPPADIGDLLEQLVEENTGSLSGPAKDFYQRGFDFFNKITNVSAVIKPYPKGDERKKACLSALSEVTVQPGCSLPSNPEAIVLDVDYKSGTPMQSAAKAPYLAKFKVKRCGVSELEKEGLRCRSDSEDECSTQEADGQKISWQAAIFKLGDDCRQKSYWGARMPTDRILRLPASQDMLALQIIDLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRDQLGRQTDFGMYDYFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDKKGHIIHIDFGFMFESSPGGNLGWEPDIKLTDEMVMIMGGKMEATPFKWFMEMCVQATWLCGEPGPYMDVVVSLVTIMLDTGLPCFRGQTIKLLKHRFSPNMTEREAANFIMKVIQSCFLSNRSRTYNMIQYYQNDIPY
What are the official names of this protein?
Putative phosphatidylinositol 4-kinase alpha-like protein P2.
What is the protein family that this protein belongs to?
Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
Protein: MDEP_STAEQ
Sequence: MKFLKNKSYHLLVTLIVLTIFVISGAIFLTFLGFGLYGLSRILIYLHLGDFSYNKGFYDNLIYYGSYIVLGYFTLFSIEHLMDYFKKNLPKNPYFQGINFHLISYIVTTIMFYFIVHIHYVHVNIHFWVIMIIIGFLFVCKEVFYPESKNLNNKK
What is the function of this protein?
Involved in multidrug efflux.
What are the official names of this protein?
Multidrug resistance efflux pump SepA, Antiseptic resistance protein SepA, Staphylococcal efflux pump A.
What is the protein family that this protein belongs to?
Belongs to the multidrug resistance efflux pump SepA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYW_METKA
Sequence: MIDPWDVEEVDYERLTEEFGIRPIDEKVRELLPRRFPLLDRGIVFGHRDYDSFLKDYNDGKLVSVLSGMMPSGRMHLGHKTVVDQLVFYQQEMDVKVYVPIADLEAHHARNMDLDRAHRIAVEEYVLNYAALGLDLDPDRCEIYLQSERKTVQRMALLLAGRLTWNTVKNTYGFTGETNMGHAFAPIVQAADILHPQEIEGPHRVLVPVGVDQDPHLRLTRDIAEKEDLIKPASTYHRFMTGLTGGKMSSSKPNTAIFLTDDPETAKEKVWNAKTGGGATLEEHREHGGNPDECVVYELMVYHLADRIGGDEKLREIRKKCREGDIICGECKRMVGEALAEILEELERRREDVRDELPDLLSQHPDAPEVPEDW
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P2RY2_CRIGR
Sequence: VHRCLGVLRPLHSLRWGRARYARRVAAVVWVLVLACQAPVLYFVTTSVRGTRITCHDTSARELFSHFVAYSSVMLSLLFAVPFSVILVCYVLMARRLLKPAYGTTGGLPRAKRKSVRTIALVLAVFTLCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKITRPL
What is the function of this protein?
Receptor for ATP and UTP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system.
What are the official names of this protein?
P2Y purinoceptor 2, P2Y2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BIOD_BURCH
Sequence: MTAPLSVFVTGTDTEIGKTFVSAAMLHGFARHGLRAAALKPVAAGAYERDGVWRNEDADQLDAAANVALPPELRTPFLLKAPAAPHIVAAQEGVTLDLDTIVACHREALTRADVVVVEGVGGFRVPLNDTQDTADLAVALGLPVVLVVGVRLGCISHALLTADAIRQRGLTLAGWVANHVDPAMSFADENVATIRDWLAREHRAPLIGRIAHMTPAAPESAAAMLDIAALVESLRTARR
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEC_BURM9
Sequence: MIRTDAKDGALVLFSGGQDSATCVAWALERYQTVETLGFDYGQRHRVELECREGVRDALKRRFPQWSHKLGDDHLIDLSVLGSISDTAMTRAIEIETASNGLPNTFVPGRNLLFMTIAAAIAYRRGLRALVGGMCETDFSGYPDCRDDTMKALQVALNLGMDTRFVLETPLMWLDKADTWRLAEQLGGAPLVELIRVETHTCYVGERSELHDWGFGCGECPACKLRKRGYDAYLRGESVTEAPA
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: URED1_PSYCK
Sequence: MTILFSMPVHPQPIIDSGHRFDASRHWPASLTLGFAAYPEADTRITRMNVARHYGPLRVQRAFYPEGRDGCCHVYLLHPPGGIASGDSLTIDVTVSENAHALLTTPAANKLYRADSNNVAWTQHTHLKVEDGATLEWLPQETLAFDGSRGEQTVIIDLAETAKCLGWEIIGLGRPASDLPYVSGMIEQRFQLSQKGRPLWLERQAIDPTHPRFLGKWGQGGATVHATLWAVGLSDPADTITELRDKIPANHNWAVTYRRGVLLLRYLGMERNEAWDLLQQAREILRPRLMDVKAVTPRIWLT
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD 1.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YEAH_ECOSM
Sequence: MTWFIDRRLNGKNKSMVNRQRFLRRYKAQIKQSISEAINKRSVTDVDSGESVSIPTEDISEPMFHQGRGGLRHRVHPGNDHFVQNDRIERPQGGGGGSGSGQGQASQDGEGQDEFVFQISKDEYLDLLFEDLALPNLKQNQQRQLTEYKTHRAGYTANGVPANISVVRSLQNSLARRTAMTAGKRRELHALEEHLAIISNSEPAQLLEEERLRKEIAELRAKIERVPFIDTFDLRYKNYEKRPDPSSQAVMFCLMDVSGSMDQSTKDMAKRFYILLYLFLSRTYKNVEVVYIRHHTQAKEVDEHEFFYSQETGGTIVSSALKLMDEVVKERYNPAQWNIYAAQASDGDNWADDSPLCHEILAKKILPVVRYYSYIEITRRAHQTLWREYEHLQSTFDNFAMQHIRDQDDIYPVFRELFHKQNATAKD
What are the official names of this protein?
UPF0229 protein YeaH.
What is the protein family that this protein belongs to?
Belongs to the UPF0229 family.
Protein: TMCA_AERPE
Sequence: MDVELEVSGFIQRLRHSRLRGLLVVGTGDVKAWAEKLAGYAGGDCALVSPSAGRLPGICRSWAPPGSIERILGGEYAAAIIAVPGLLRPSIIAGAGETVRSGGFLAIVADPPDRWDPGPPRGTGLYREYLFSAIRDNPVHLWIDDESGRIVSESFLEYTGVGAQGWSPGRYKPSPGSGVPRRLVSACRSESQARALESLARFFRGRWRSALVRGDRGRGKSYVIGLALAYAAWRRLIGRAVLVGPTPLSVQSVMAGLLRGLDVLGLKGHRVVRTSGGEVIRVSGPWFRIAYEQPDTAEPSPLVVVDEAAAVGVARVRRLSWRSGKSLVATTIHGYEGSGRAFARLLPNILPKPFIELELREPIRYLPGDPLEEWLYTVFMLRAEPQEPGDPSAARPVEVSREVLARDREVLRSVYGILVQAHYRNTPDDLLAMLESPHHRIYALEADGTPVAVADVVLEGPDVEEEARIALERLLYMAGSPGSGVVSWRVSRIAVHEDLQRRGLGSRLLRHVEAQARESGASLVTTMFSRHDVIPFWLKNGFKPFYVSPRYNRVTGEKNVALAKPLDSAGAEILEKASKTLALKLALAGSSIYRDLAAEKLALLLHHTPATAPPLYLTRIQARHLEGFLKGEVMADQAFDAVYIALLSTLLATRSWNPVEPGLVGAVARVVQGKPYSEVASIIGASTVDEAVGKVEEYIRGILEGARSLWSGRVIP
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
What are the official names of this protein?
tRNA(Met) cytidine acetyltransferase TmcA.
What is the protein family that this protein belongs to?
Belongs to the RNA cytidine acetyltransferase family. TmcA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPRA_MYCTU
Sequence: MKHPPCSVVAAATAILAVVLAIGGCSTEGDAGKASDTAATASNGDAAMLLKQATDAMRKVTGMHVRLAVTGDVPNLRVTKLEGDISNTPQTVATGSATLLVGNKSEDAKFVYVDGHLYSDLGQPGTYTDFGNGASIYNVSVLLDPNKGLANLLANLKDASVAGSQQADGVATTKITGNSSADDIATLAGSRLTSEDVKTVPTTVWIASDGSSHLVQIQIAPTKDTSVTLTMSDWGKQVTATKPV
What is the function of this protein?
Constitutes a host TLR2 agonist (toll-like receptor), shown experimentally for human and mouse (PubMed:19362712).  In host cells full-length (acylated) protein acts as a TLR2 agonist, inducing human and murine macrophages to produce cytokines, inducing murine dendritic cell maturation and cytokine production and inhibiting antibody processing in murine macrophages (PubMed:16785538).  Binds diacylated phosphatidyl-myo-inositol mannosides (PIMs) (PubMed:20694006).  Does not induce murine macrophage apoptosis or necrosis (PubMed:16785538).  Non-acylated protein does not act as a TLR2 agonist (PubMed:20694006).  Requires only host TLR2 as receptors to elicit host response in mouse, although TLR6 may play a redundant role, also requires CD14 and CD16 as accessory receptors (PubMed:19362712).
What are the official names of this protein?
Lipoprotein LprA.
What is the protein family that this protein belongs to?
Belongs to the LppX/LprAFG lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Note=May be shed from the cell surface in infected host cells.
Protein: RS13_BLOFL
Sequence: MVRIAGVNVPDRKHAVIALMSIYGIGRSRAKLICLSIGVDEYTKIGQLSDVYIDKMRNEIAKYVVEGDLRREVTLNIKRLIDLGTYRGLRHRRNLPVRGQRTRTNARTRKGPKKLINK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: MEND_SACEN
Sequence: MNPSTAQAEVLVDELVRNGVRQVVLAPGSRNAPLSFALHDAAEAGRLDLHVRIDERSAGFLALGIATRTRRPVVVVCTSGTAATNLHPAVSEACHAGIPLIVLTADRPPELRAAGANQTIDQYRLYGTEVRLFDELAVAENRPGQNAYWRTQVCRAASMAAGTTWGGPVHLNLPFREPLVPSGDRDWCEPLDGRADGQRWTEVSGNESAPSTLSKVRSRRGLVLVADGGADSASAWGERYGWPVLSETGGVGLSGAAAISTGMWLLKLPGFMRDHRPEQVLCVGRNTVFRQVQSLLADSEVEVLLAHGGSHWPTPAHNVREVAETFGASPGPADPDWLTGWQQADQKASAALHAALDLERWPNGPVVARDVVDALPAGSLLVLGSSNPTRDVALAANHRPDVVVHRNRGVAGIDGTVSAAIGSALAHGGPSYALLGDLTFLHDSNGLMLGPQEQRPDLTIVVLNDDGGGIFSLLEQGSPEHRGSFERVFGTPHGTDIGSLCAAHGVEHTVVRQRSEFGVALRRRPGLRVVEVRADRAELRGVHERLHAAVRGALHG
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: AT5G3_RAT
Sequence: MFACAKLACTPSLIRAGSRVAYRPISASVLSRPEASRTGEGSTVFNGAQNGVSQLIQREFQTSAISRDIDTAAKFIGAGAATVGVAGSGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMVAFLILFAM
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
What are the official names of this protein?
ATP synthase F(0) complex subunit C3, mitochondrial, ATP synthase lipid-binding protein, ATP synthase membrane subunit c locus 3, ATP synthase proteolipid P3, ATPase protein 9, ATPase subunit c.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
Protein: CLPS_LEGPL
Sequence: MSRQNLEEIIQTGIADTELSTEISTAIKRPRKYKVLLLNDDYTPMDFVVEVLKHFFHLNEEVAIQVMLQVHFQGKGVCGVFTRDIAETKVALVNEYARMNQHPLLSSMEPE
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: YACL_ECO55
Sequence: MDYEFLRDITGVVKVRMSMGHEVVGHWFNEEVKENLALLDEVEQAAHALKGSERSWQRAGHEYTLWMDGEEVMVRANQLEFAGDEMEEGMNYYDEESLSLCGVEDFLQVVAAYRNFVQQK
What are the official names of this protein?
UPF0231 protein YacL.
What is the protein family that this protein belongs to?
Belongs to the UPF0231 family.
Protein: DDHD1_MOUSE
Sequence: MDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEATLEDKPSQTSHIVFVVHGIGQKMDQGRIIKNTAMMREAARKMEEKHFSNHATHVEFLPVEWRSKLTLDGDTVDSITPDKVRGLRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYSLFCSRNPDFEEKGGKVSIVSHSLGCVITYDIMMGWNPGGLYEQLLQKEEELPDERWMSYEERHLLDELYITKRRLREIEDRLHGLKAPSISQTPALKFKVENFFCMGSPLAVFLALRGIRPGNSGSQDHILPREICNRLLNIFHPTDPVAYRLEPLILKHYSNISPVQIHWYNTSNPLPYEHMKPNFLNPAKEPTSVSDSENIAAIPSPVTSPVLSRRHYGESITNIGKASILGAASIGKGLGGMLFSRFGRSSASQPSEPSKDSLEDDKKPSASPSTTTVATQTLPHSGSGFLDSAYFRLQESFFYLPQLLFPENVMQSKDDSLVELEHRIDFELREGLVESRYWSAVTSHTAYWSSLDVALFLLTFMYKHEHDTEAKPSLGSL
What is the function of this protein?
Phospholipase A1 (PLA1) that hydrolyzes ester bonds at the sn-1 position of glycerophospholipids producing a free fatty acid and a lysophospholipid (PubMed:30221923).  Prefers phosphatidate (1,2-diacyl-sn-glycero-3-phosphate, PA) as substrate in vitro, but can efficiently hydrolyze phosphatidylinositol (1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol), PI), as well as a range of other glycerophospholipid substrates such as phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine, PC), phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine, PE), phosphatidylserine (1,2-diacyl-sn-glycero-3-phospho-L-serine, PS) and phosphatidylglycerol (1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol), PG) (PubMed:30221923) (By similarity).  Involved in the regulation of the endogenous content of polyunsaturated PI and PS lipids in the nervous system (PubMed:30221923).  Changes in these lipids extend to downstream metabolic products like PI phosphates PIP and PIP2, which play fundamental roles in cell biology (PubMed:30221923).  Regulates mitochondrial morphology (PubMed:24599962).  These dynamic changes may be due to PA hydrolysis at the mitochondrial surface (PubMed:24599962).  May play a regulatory role in spermatogenesis or sperm function (PubMed:24599962).
What are the official names of this protein?
Phospholipase DDHD1, DDHD domain-containing protein 1, Phosphatidic acid-preferring phospholipase A1 homolog, PA-PLA1, Phospholipid sn-1 acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the PA-PLA1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSTB_NOVAD
Sequence: MNAEAIQTPMTVDVKADDKPYFDAPSKMSAKNVSVFYGDKRAIDDVSIEIPQRYVTAFIGPSGCGKSTFLRSLNRMNDTIANARVEGEILLDGEDIYKSGMDVVQLRARVGMVFQKPNPFPKSIYENIAYGPKIHGITGSKAELDEIVEQSLRRAGLWDEVKDRLGDSGTALSGGQQQRLCIARAIAVDPEVILMDEPCSALDPIATARIEELIDELRGRYAIVIVTHSMQQAARVSQRTAFFHLGKIVEYGKTSDIFTNPREERTKDYITGRYG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.