PharMolix/UniProtQA huggingface dataset:
Protein: TRISR_DROME
Sequence: MIMTMMQTVRAWQQESDVEHRKQHKQRWRPDGAHISAAYDLNSDNDDGHHRVVHNQNNGSPNSSPNQSTSAFRQRQPHHPPTGQQPPRLPCTVTHFSAHWKTLLILLTLLSASTLTASANVTSTISPPINGSSTDYILLYGESTTSLVPALTTGLSGDGSGAVIEDEEDAEKASEYIFDRTDVRIIFITLYTLVFCCCFFGNLLVILVVTLSRRLRSITNFFLANLAFADFCVGLFCVMQNLSIYLIESWVFGEFLCRMYQFVHSLSYTASIFILVVICMERYFAIVHPITCKQILTAARLRMVIVTVWITSAVYSTPKFVFSKTIKNIHTQDGQEEEICVLDREMFNSKLLDMINFVLLYVMPLLVMTVLYSKIAIALWRSSRGLTPHVVQHQHQQPQQPSCQDIGMGMHNSMYHHHPHHHHHHHQHHQLQSAASSAGVVGVGLGGGGGGGPGPSLASGGSSTTSLSRKQSSKYEKRGVSITESQLDNCKVSLEADRPIVSACRKTSFYHHGHAHHQRAGNASVGGGSGGAGAGATHMSHSSSNVLRARRGVVRMLIIFVLTFALCNLPYHARKMWQYWSRSYRGDSNFNALLTPLTFLVTYFNSGVNPLLYAFLSRNFRKGMKELLLCSWKKGKGKSSSNSSMHHKRKALQTHSLPTDTTHIGNEQL
What is the function of this protein?
G-protein coupled receptor which is activated by the Trissin peptide in vitro, leading to increased intracellular calcium ion levels.
What are the official names of this protein?
Trissin receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HSCA_SHESM
Sequence: MALLQIAEPGQSAAPHQHRLAVGIDLGTTNSLVAAVRSGVTATLPDENGQHSLPSIVRYTQDGIEVGQVAALSSAQDPKNTIVSVKRFMGRSLTDIQSGEQAFPYQFEASENGLPLFVTPQGQVNPVQVSAEILRPLVERAEKTLGGELQGVVITVPAYFDDAQRQGTKDAASLLGVKVLRLLNEPTAAAIAYGLDSKQEGVIAIYDLGGGTFDISILRLNRGVFEVLATGGDSALGGDDFDHLLQAHMQQVWQLTNLDPQLSRQLLIEARRVKEALTDASDVEASLTLADGTVLKQVVTKAEFDNLISALVKKTIASCRRTLRDAGVTADEVLETVMVGGSTRVPLVREQVEAFFGKAPLTSIDPDRVVAIGAAIQADILVGNKPESELLLLDVIPLSLGIETMGGLVEKVVSRNTTIPVARAQEFTTFKDGQTAMAFHVVQGERELVDDCRSLARFTLKGIPPLAAGAAHIRVTFQVDADGLLSVTAMEKSTGVQSSIQVKPSFGLSDTEIATMLKDSMKHAKEDISRRMLAEQQVEAARVLESLNAALAKDGDLLTSDERQQIDAVMAQLAEIARGDDADAIKQAIEVLDEHTQDFAAKRMDNSIRVAFKGQSIDNI
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RL20_FRASN
Sequence: MARVKRAVNAQKKRREVLEAASGYRGQRSRLYRKAKEQMLHSMTYSYRDRRARKGDFRQLWITRINAAARANGLTYNRFVQGLRLAGVEVDRKILADLAVNDAAAFAALVEVARAALPAAAETSAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: CP4F6_RAT
Sequence: MLQLSLSRLGMGSLTASPWHLLLLGGASWILARILAWIYTFYDNCCRLRCFPQPPKPSWFWGHLTLMKNNEEGMQFIAHLGRNFRDIHLSWVGPVYPILRLVHPNVIAPLLQASAAVAPKEMTLYGFLKPWLGDGLLMSAGEKWNHHRRLLTPAFHFDILKSYVKIFNKSVNTMHAKWQRLTAKGSARLDMFEHISLMTLDSLQKCIFSFDSNCQESNSEYIAAILELSSLIVKRQRQPFLYLDFLYYLTADGRRFRKACDVVHNFTDAVIRERRSTLNTQGVDEFLKARAKTKTLDFIDVLLLAKDEHGKGLSDVDIRAEADTFMFGGHDTTASALSWILYNLARHPEYQERCRQEVRELLRDREPEEIEWDDLAQLPFLTMCIKESLRLHPPVLLISRCCSQDIVLPDGRVIPKGNICVISIFGVHHNPSVWPDPEVYNPFRFDPENPQKRSPLAFIPFSAGPRNCIGQTFAMSEIKVALALTLLRFCVLPDDKEPRRKPELILRAEGGLWLRVEPLSTVTSQLPWDLLAHPPTS
What are the official names of this protein?
Cytochrome P450 4F6, CYPIVF6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: MIAB_XYLF2
Sequence: MTGTSNIPTHGKEHKDAPALLPLPAPNTHHTHAAHPGDPSHDRHPSRGKLFIKTHGCQMNEYDSAKMADVLTTTEALELTDNPEEADIILINTCSIREKAQEKVFSQLGRWRALKTNGRDVIIGVGGCVASQEGETIVKRAPYVDLVFGPQTLHRLPDMIRARREQNRPQVDISFPEIEKFDHLPTPRAEGPSAFVSIMEGCSKYCSFCVVPYTRGEEVSRPFEDVLTEIAHLATQGVREINLLGQNVNAYRGAMDPGPSNNTNPAPPPYADLGLLIRAIAQFESIGRIRFTTSHPLEFSDSLVEAYRDVPQLANHLHLPVQSGSDRILSAMKRGYTALEFKSKIRKLRAVRPDISISSDFIIGFPGESDTDFQKTMQLIKDIGFDQSFSFIYSRRPGTPASNLEDHTPDEIKRTRLEHLQKHINAYAADISKRMIGTVQTVLVEGPSKKNPNELTGKTENMRPVNFPGHPRLIGQFIDVHITEALTNSLRGRVHTN
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPO3A_SYNY3
Sequence: MSFVGLHIHSDYSLLDGASQLPALIDRAIELGMPAIALTDHGVMYGAVELLKVCRGKPIKPIIGNEMYVINGDIEINKRHRRFHQVVLAKNNQGYRNLVKLTTISNLKGIQGSGIFARPCINKELLEQYKEGLIVTSACLGGEVPQAILKGDLDHARQVAKWYKNLFGDDYYLEIQDHGSVEDRLVNINLVKIAQELDIKIVATNDSHFISCNDVEAHDALLCIQTGKLITEEKRLRYSGTEYLKSAEEMHLLFRDHLPDDIIETAIANTLEVADKVEAYSILGEPRIPHYPIPPNHTPETYVEDIAWDGLLERLKCRERADITPVYKERLEYELRMLEKMGFCTYFLVVWDYIKYARDHGIPVGPGRGSAAGSLVAYCMKITNIDPVHHGLIFERFLNPERKSMPDVDTDFCIDRRDEMIEYVTQKYGEDKVAQIITFNRMTSKAVLKDVARVLDIPYAESDKMAKMIPVSRGKPAKLKVMISDQTPEPQFKARYDNEPWVKKWIDMAIRIEGTNKTFGVHAAGVVISSEPLDQIVPLQKNNDGAVITQYYMEDVEAMGLLKMDFLGLKNLTTLQRAVELVAETKGIELDLDDLPLQERKALQIRARTGSKKLPDDVKKTHKLLEAGDLEGIFQLESQGMKQIVRDLKPSGIEDISSILALYRPGPLDAGLIPIFINRKHGREEISYQHKLLEPILNETYGVLVYQEQIMKMAQDLADYSLGEADLLRRAMGKKKAEEMQKHRAKFVDGSTKHGVPSRIAENLFDQMVKFAEYCLSFGTEILTVEYGPLPIGKIVSEEINCSVYSVDPEGRVYTQAIAQWHDRGEQEVLEYELEDGSVIRATSDHRFLTTDYQLLAIEEIFARQLDLLTLENIKQTEEALDNHRLPFPLLDAGTIKMVKVIGRRSLGVQRIFDIGLPQDHNFLLANGAIAANCFNKSHSTAYAYVTYQTAYLKANYPVEYMAALLTASSDSQEKVEKYRENCQKMGITVEPPDINRSQRHFTPLGEAILFGLSAVRNLGEGAIEQIITARDNSEEKRFKSLADFCTQVDLRVVNRRAIETLIMAGAFDGVQSNRNQLLHDLELVIAWAQKRAKEKETGQLNIFDSLTAGESIKAKEAANNGFEQEPSAPPVAEFSLQEKLQLEKEHLGFYVSEHPLKSVQRSARLLSPINLVDLDQYKVRQKVSAVAILVAVKKIITKKNGQPMAFLTLEDMSGQSEAVVFPSNYERLQDVLIEGSQQMIWGKVDRRDDQYQLIVEDLEPVEEVKMVMLDLTPQEIANTSTQARLKQILQSHAPQKEQMKIPVVACINEGPTKHFIRFGENYWVNDYGTAVASLQELGFRARLEPLLPQSQSVG
What is the function of this protein?
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.  The alpha chain is the DNA polymerase (By similarity).
What are the official names of this protein?
DNA polymerase III subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. DnaE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_RHIE6
Sequence: MAQTLSFNGRRRVRKFFGKIPEVAEMPNLIEVQKASYDQFLMVEEPKGGRPDEGLQAVFKSVFPITDFSGASMLEFVSYEFEPPKFDVDECRQRDLTYAAPLKVTLRLIVFDIDEDTGAKSIKDIKEQSVYMGDMPLMTNNGTFIVNGTERVIVSQMHRSPGVFFDHDKGKSHSSGKLLFAARVIPYRGSWLDIEFDAKDIVYARIDRRRKIPVTSLLMALGMDGEEILDTFYTKSLYKRDGEGWRIPFKPETLKGAKAITEMVDADTGEVVVEAGKKLTPRLLRQLSDKGLKALKAGDDDLYGNYLAEDIVNYSTGEIYLEAGDEIDEKTLGIILSNGFDEIPVLGIDHINVGAYIRNTLSADKNENRQDALFDIYRVMRPGEPPTMESAEAMFNSLFFDAERYDLSAVGRVKMNMRLDLTVEDTVRILRKDDILAVVKMLVELRDGKGEIDDIDNLGNRRVRSVGELMENQYRLGLLRMERAIKERMSSIEIDTVMPQDLINAKPAAAAVREFFGSSQLSQFMDQVNPLSEITHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGPNIGLINSLATFARVNKYGFIESPYRRIVDGKVTNDVLYLSAMEEAKYYVAQANAEMNPDGSFVDEFVVCRHAGEVMLAPRDSMNLMDVSPKQVVSVAAALIPFLENDDANRALMGSNMQRQAVPLLRAEAPFVGTGMEPVVARDSGAAIGARRGGVVDQVDATRIVIRATEDLEAGKSGVDIYRLQKFQRSNQNTCVNQRPLVTVGDVVNRGDILADGPSTDLGDLALGRNALVAFMPWNGYNYEDSILLSERIVADDVFTSIHIEEFEVMARDTKLGPEEITRDIPNVSEEALKNLDEAGIVYIGAEVQPGDILVGKITPKGESPMTPEEKLLRAIFGEKASDVRDTSMRMPPGTYGTIVEVRVFNRHGVEKDERAMAIEREEIERLAKDRDDEQAILDRNVYGRLIDMLRGQVSIAGPKGFKKGTELSNAVVSEYPRSQWWMFAVEDEKVQSELEALRGQYDESKSRLEQRFMDKVEKVQRGDEMPPGVMKMVKVFVAVKRKIQPGDKMAGRHGNKGVVSRIVPVEDMPFLEDGTHVDVVLNPLGVPSRMNVGQILETHLGWACAGMGRQIGELIEAYKANGNIEPLRKTIGDVVGAGPKAEQVHEFDDDSVLRLADQWKRGVSIATPVFDGANEGDVNDMLRLAGLKDTGQSTLYDGRTGEQFDRQVTVGYIYMLKLNHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKVYEAIVRGDDTFEAGIPESFNVLVKEMRSLGLSVELENTKLDEAQANQLPDAAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: CAVN1_RAT
Sequence: MEDVTLHIVERPYSGYPDASSEGPEPTPGEARATEEPSGTGSDELIKSDQVNGVLVLSLLDKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSVSKSLKESEALPEKEGDELGEGERPEEDAAAIELSSDEAVEVEEVIEESRAERIKRSGLRRVDDFKKAFSKEKMEKTKVRTRENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPVERREKLKTSRDKLRKSFTPDHVVYARSKTAVYKVPPFTFHVKKIREGEVEVLKATEMVEVGPDDDEVGAERGAETDLLRGSSPDVHTLLEITEESDAVLVDKSDSD
What is the function of this protein?
Plays an important role in caveolae formation and organization.  Essential for the formation of caveolae in all tissues.  Core component of the CAVIN complex which is essential for recruitment of the complex to the caveolae in presence of calveolin-1 (CAV1).  Essential for normal oligomerization of CAV1.  Promotes ribosomal transcriptional activity in response to metabolic challenges in the adipocytes and plays an important role in the formation of the ribosomal transcriptional loop.  Dissociates transcription complexes paused by DNA-bound TTF1, thereby releasing both RNA polymerase I and pre-RNA from the template.  The caveolae biogenesis pathway is required for the secretion of proteins such as GASK1A.
What are the official names of this protein?
Caveolae-associated protein 1, Cavin-1, Polymerase I and transcript release factor, cav-p60.
What is the protein family that this protein belongs to?
Belongs to the CAVIN family.
What are the subcellular locations of this protein?
Membrane, caveola. Cell membrane. Microsome. Endoplasmic reticulum. Cytoplasm, cytosol. Mitochondrion. Nucleus. Note=Translocates to the cytoplasm from the caveolae upon insulin stimulation (By similarity). Colocalizes with CAV1 in lipid rafts in adipocytes (PubMed:18056712). Localizes in the caveolae in a caveolin-dependent manner (By similarity).
Protein: NUDC_PASMU
Sequence: MNAIQPDDAGYWLLTQDSALYLINGELPQGKAADFQLQGYNGMIIGELNGRPLWLVEEIADDQRTYFSLRSLLALPEAHFNLLNRGVELNHFFKTHRFCGKCGHPTDLVQQEWAIQCQNPSCSHRTYPVICPCIIVAVRRGAQILLANHQRHKGGIYTTLAGFVEVGETFEQAVHREVLEETGIQIQNLRYFGSQPWAFPNSAMIGFLADYAGGEICVQEMEIHDAQWFDYNAPLPELPPKGTIALKLIEHTLQLCAEEERKAT
What is the function of this protein?
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.  The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing.  Has preference for mRNAs with a 5'-end purine.  Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.
What are the official names of this protein?
NAD-capped RNA hydrolase NudC, DeNADding enzyme NudC, NADH pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudC subfamily.
Protein: GLYA_MYCMS
Sequence: MNTKISPLIKESLNKELKRQQSHIELIASENYVSKAVLELNGSVLTNKYAEGYPGKRYYGGCEFIDEIESLGIQTAKELFHAEHANIQPHSGSQANDAAYKALLEPKDRVVAMSLDAGGHLTHGYPINFSGYTYDFRFYGVNKDTEQLDYQEIEKIVLEHKPKLIVAGASAYSRIIDFKKFKEIADKVGAYLMVDMAHIAGLVAAGVHPNPLEYADIVTTTTHKTLRGARGGLILCKQEFAKKVDLAVFPGSQGGPLENLIAGKTQALLEASTDEFKEYGKQIVKNTKALANVLQENGLRLVAGGSDNHLINVDVKSTLRITGKKAEKILESIGIICNKNMIPFDTEKPFYTSGIRLGTPAMTTRGFKEEEFKQVGLIIVNALKDPSEENLEKLAKQVTSLCEKFPIYQNIKY
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF3_STRP3
Sequence: MSLTEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVKGKKSGTFAKSDWMDIEKQRGISVTSSVMQFDYAGKRVNILDTPGHEDFSEDTYRTLMAVDAAVMVVDSAKGIEAQTKKLFEVVKHRNIPVFTFINKLDRDGREPLELLEELEEVLGIASYPMNWPIGMGRAFEGLYDLHNKRLELYKGDERFASIEDGDQLFANNPFYEQVKEDIELLQEAGNDFSEQAILDGDLTPVFFGSALTNFGVQTFLDTFLEFAPEPHGHKTTEGNVVDPLAKDFSGFVFKIQANMDPKHRDRIAFVRIVSGEFERGMGVNLTRTGKGAKLSNVTQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVSPKNVMKQKSFHKGIEQLVQEGAIQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAEVVMTPMGKKTVRWISEDDLDQRMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDVTLEEKM
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2B4_CHLRE
Sequence: MAPKKDEKPATAEAGAEAPAKAEAKPKAEKAAKKAKKEPSKKAAKEPKGDGEKKDKKKKKSAVETYKLYIYKVLKQVHPDTGISSKAMSIMNSFINDIFEKVATEASKLSRYNKKPTVTSREIQTAVRLVLPGELAKHAVSEGTKAVTKFTSG
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.4, H2B-IV.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: TRMFO_BACC0
Sequence: MTTQVVNVIGAGLAGSEAAYQIAKRGVQVRLYEMRPVRQTPAHHTDKFAELVCSNSLRANTLTNAVGVIKEEMRLMDSVIIRAADECSVPAGGALAVDRHEFAAKVTEYVKNHPNVTVMNEEITEIPEGPTIIATGPLTSPDLSAQLKELTGEDYFYFYDAAAPIVEKDSIDMNKVYLKSRYDKGEAAYLNCPMTEEEFDRFYEALIAAETVPLKEFEKEIFFEGCMPVEVMASRGRQTLVFGPMKPVGLEDPKTGKTPYAVVQLRQDDAAGTLYNIVGFQTHLKWGPQKEVLQLIPGLENAEIVRYGVMHRNTFINSPNLLRPTYQYKQRDDLFFAGQMTGVEGYVESAASGLLAGINAARLVKGEEPVVLPPVTAMGSMANYITATNAKNFQPMNANFGLFAPLEKKIKKKAERNEAYATRALETIRNFVNI
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSK2_YEAST
Sequence: MTYPVSAAAPADISYSKNTPLVGLSKPPCLYQHASSSVDSFSSTFSDDDRSDLVAVPNESPHAFSYNPISPNSLGVRLTILRRSLEIMVNSPDILHELKKKAPVIAYPPSLRHTRNLTETATLSASRDPLNGSLISPLVSNMPSPASRPVIQRATSLMVLPDNDTASKLNPAKSELENLLFLLNLALENNSFERASDLHMLSLLNIKKINFDSDIQKSETLKKVLLDSLAEPFFENYKKFPHKDLGSKSQYNEYEEKHDDIVSLADIKPQQDYSRILHPFTSAKNSGPEAIFTCSQQYPWNFKAANDLACLTFGISKNVIKALTLLDLIHTDSRNFVLEKIMNAEDDNQEIVFTGETIPIVQPNSTSNNNVPNLIWASLWAKRKNGLLVCVFEKTPCDYIDVMLNLRDFSVDSIIDTTHFLENFDKKKQQESTSPMTEKKTVKFANEIHDIGSVSHSLSKLIDDVRFGKVFSADDDLLPLSIRVANHVNEERYFTLNCLSENIPCAVTTSVLENEIKLKIHSLPYQAGLFIVDSHTLSLLSFNKSVAKNMFGLRLHELAGSSVTKLVPSLADMISYINKTYPMLNITLPENKGLVLTEHFFRKIEAEMHHDKDSFYTSIGLDGCHKDGNLIKVDVQLRVLNTNAVLLWITHSRDVVIENYTTVPSQLPMLKENEIDVVGSRGSSSASSKKSSEKIPVNTLKAMADLSISSAETISNSDDEVDLNQVNEKLRETSCGKVRGIESNDNNNYDDDMTMVDDPELKHKIELTKMYTQDKSKFVKDDNFKVDEKFIMRIIEPINGEEIKKETNELDKRNSTLKATYLTTPEANIGSQKRIKKFSDFTILQVMGEGAYGKVNLCIHNREHYIVVIKMIFKERILVDTWVRDRKLGTIPSEIQIMATLNKNSQENILKLLDFFEDDDYYYIETPVHGETGSIDLFDVIEFKKDMVEHEAKLVFKQVVASIKHLHDQGIVHRDIKDENVIVDSHGFVKLIDFGSAAYIKSGPFDVFVGTMDYAAPEVLGGSSYKGKPQDIWALGVLLYTIIYKENPYYNIDEILEGELRFDKSEHVSEECISLIKRILTREVDKRPTIDEIYEDKWLKI
What is the function of this protein?
Serine/threonine-protein kinase involved in the control of sugar metabolism and translation.  Phosphorylates UGP1, which is required for normal glycogen and beta-(1,6)-glucan synthesis.  This phosphorylation shifts glucose partitioning toward cell wall glucan synthesis at the expense of glycogen synthesis.  Phosphorylates also the glycogen synthase GSY2 and the translation factors CAF20, TIF11 and SRO9.
What are the official names of this protein?
Serine/threonine-protein kinase PSK2, PAS kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_STRPZ
Sequence: MSSGKIAQVVGPVVDVMFASGDKLPEINNALIVYKDSDKKQKIVLEVALELGDGMVRTIAMESTDGLTRGLEVLDTGRAISVPVGKETLGRVFNVLGETIDLEEPFAEDVDRQPIHKKAPSFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVGKTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEPPGARMRVALTGLTIAEYFRDVESQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTQKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLTQMGIYPAVDPLASSSRALSPEIVGEEHYAVATEVQRVLQRYRELQDIIAILGMDELSDEEKTLVGRARRIQFFLSQNFNVAEQFTGLPGSYVPVAETVRGFKEILEGKYDHLPEDAFRSVGPIEDVIKKAEKMGF
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TRHO_LEPBJ
Sequence: MANRGDLQKKTHTKKRPLHNIYGKEILSKRLEAENFPRTTLSFYRYVILENVQELRNRLYVEWEALGVLGRIYVAREGINAQLSIPSHNLNSFKENLNSRIQFKDMLLKIAVEDDHRSFLKLDLKVRNKIVADGLNDDAFDVTNVGKHLSAEEFNRCMEDKNSIVVDVRNHYESEIGHFENAILPQSDTFREELQILLELLNGKEDHKILMYCTGGIRCEKASAWLKHHGFKDVNQLHGGIISYAHEISQKGLESKFRGKNFVFDGRLQETIGNEIISVCHQCGKKSDRHINCSNPGCHILFIQCDDCSEKFEGCCTEECKTVLHLPKEKQKEIRKGKSNENRFFTKSKIRPKISELYRNRKPFETA
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: RSMC_HAEDU
Sequence: MLSLKSEVLARHLPLFNGKSILLFGNVRDRFADQIRSISSHVAIFSHYFDYARHYNDVEFGLDCTTPANLGVFYWTKNKQECHYQLLQWLSQTAIGQQMLIIGENRAGVRSVEKLLSPFGQIAKIDSARRCGLYHFELQTIPQFDCQKFWKSYRLADLTVLSLPAAFSSTELDAGSQLLLSSFTNQDRLTGNVLDLGCGAGVIGAYLKQRFPAISLTMSDIHSMAIHSAQATLAKNKLTGTVIASDVFSHINDRFDLIVSNPPFHDDIDTAYHTVESLIMQAKNHLNYGGELRIVANAFLPYPDLLDKAFGSHQVVTKSNKFKVYSARV
What is the function of this protein?
Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase C, 16S rRNA m2G1207 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RsmC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOB_NOCFA
Sequence: MGLEEKLPSGFLLSTVESFAGYLRKGSVWPATFGLACCAIEMMATGAGRFDIARFGMEAFRASPRQADLMIVAGRVSQKMAPVLRQVYDQMAEPKWVLAMGVCASSGGMFNNYAVVQGVDHVVPVDIYLPGCPPRPEMLLNAILALHDKIQHTPLGVNRQEAVRAAEQAALAATPTIRMEGLLR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RFA4_HUMAN
Sequence: MSKSGFGSYGSISAADGASGGSDQLCERDATPAIKTQRPKVRIQDVVPCNVNQLLSSTVFDPVFKVRGIIVSQVSIVGVIRGAEKASNHICYKIDDMTAKPIEARQWFGREKVKQVTPLSVGVYVKVFGILKCPTGTKSLEVLKIHVLEDMNEFTVHILETVNAHMMLDKARRDTTVESVPVSPSEVNDAGDNDESHRNFIQDEVLRLIHECPHQEGKSIHELRAQLCDLSVKAIKEAIDYLTVEGHIYPTVDREHFKSAD
What is the function of this protein?
As part of the alternative replication protein A complex, aRPA, binds single-stranded DNA and probably plays a role in DNA repair.  Compared to the RPA2-containing, canonical RPA complex, may not support chromosomal DNA replication and cell cycle progression through S-phase.  The aRPA may not promote efficient priming by DNA polymerase alpha but could support DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange.
What are the official names of this protein?
Replication protein A 30 kDa subunit, RP-A p30, Replication factor A protein 4, RF-A protein 4.
What is the protein family that this protein belongs to?
Belongs to the replication factor A protein 2 family.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes to DNA repair foci after DNA damage.
Protein: YWMF_BACSU
Sequence: MFGFNDMVKFLWSFLIVLPLVQIIHVSGHSFMAFIFGGKGSLDIGMGKTLLKIGPIRFRTIYFIDSFCRYGELKIDNRFSNALVYAGGCLFNLITIFAINLLIIHSVLKPNVFFYQFVYFSTYYVFFALLPVRYSEKKSSDGLAIYKVLRYGERYEIDK
What are the official names of this protein?
Uncharacterized membrane protein YwmF.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MURA_CHLTA
Sequence: MPGIKVFGETVLRGSVRVSGAKNATTKLLVASLLSDQRTILKNVPNIEDVRQTVDLCRVLGAIVEWDQQAQVIEIHTPRILLSKVPPQFSCVNRIPILLLGALLRRCPYGIFVPILGGDAIGPRTLHFHLEGLKKLGAEIVISDEGYWASAPNGLVGAHITLPYPSVGATENLILASVGAQGRTIIKNAALEVEIIDLIVFLQKAGMEITTDNDKTIEIFGCQDFYSVEHSIIPDKIEAASFGMAAVVSQGRIFVEQARHEHMIPFLKVLRSIGGGFSVHENGIEFFYDKPLKGGVLLETDVHPGFITDWQQPFAVLLSQSEGCSVIHETVHENRLGYLKGLVKMGAHCDLFHECLSAKSCRYSTGNHPHSAVIHGPTPLQATDLVIPDLRAGFAYVMAALITEGGASWIENTEMLDRGYTDWRGKLERLGAKVLARDSVSVYV
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCUP_BRUA4
Sequence: MKRKVLRVIDGETVFPPPIWMMRQAGRYLPEYRETRKKAGSFLDLCYSPDLAVEVTLQPIRRFGFDAAILFSDILVIPHALGRDLRFEEGKGPLMTPIDADEIFWLETEGVAKRLEPVYETVRLLREQLPDETTLLGFCGAPWTVATYMIAGHGTPDQAPARLFAYRFPEAFEKLLNDLADVSAEYLIEQLDAGADAVQIFDSWSGVLDEDCFERFCIRPVARIVQKVRAVYPEARIIGFPKGAGMLYAGYREKTGVDALGLDWSVPFSFAAALQEEGAIQGNLDPLRVVAGGNALDEGVDTILERLGQGPLIFNLGHGITPQAPIENVQRMIDRIRGGKS
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.