PharMolix/UniProtQA huggingface dataset:
Protein: Y949_METPE
Sequence: MAEIKSKVTLIGAMLARPGLEFIYEGELPACEQCKVRKACNNLKVGRKYRVLSIRATVHGCSVHLNGACAVEIVESPMVGLIKADLAIANSRILPDLSCTQSECKSYPLCHPDGVVSGERYMVSEVLGNAPDHCDKGRSLKLVELLPI
What are the official names of this protein?
UPF0179 protein Mpal_0949.
What is the protein family that this protein belongs to?
Belongs to the UPF0179 family.
Protein: FINC_HUMAN
Sequence: MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMIWDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHMLNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDTTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNVIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE
What is the function of this protein?
Binds fibronectin and induces fibril formation.  This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties.  Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis.  Anastellin activates p38 MAPK and inhibits lysophospholipid signaling.
What are the official names of this protein?
Fibronectin, FN, Cold-insoluble globulin, CIG.
Protein: RL22_HALMA
Sequence: MGISYSVEADPDTTAKAMLRERQMSFKHSKAIAREIKGKTAGEAVDYLEAVIEGDQPVPFKQHNSGVGHKSKVDGWDAGRYPEKASKAFLDLLENAVGNADHQGFDGEAMTIKHVAAHKVGEQQGRKPRAMGRASAWNSPQVDVELILEEPEVED
What is the function of this protein?
Contacts all 6 domains of the 23S rRNA, helping stabilize their relative orientation.  An extended beta-hairpin in the C-terminus forms part of the polypeptide exit tunnel, in which it helps forms a bend with protein L4, while most of the rest of the protein is located at the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L22, Hl23, Hmal22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: HTPX_BORPD
Sequence: MKRIFLFIVTNLAVMVVLSATLRVLGVDRYITAQGINFQSLLILSVVIGFTGAIISLLISKPMAKWSTGARVIDPAAPGGSREAWLVETVHQLADRAGIGHPEVAIYDGSPNAFATGAFKNDSLVAVSTGLLDSMTEEEVAAVLGHEVAHIANGDMITLTLIQGVVNTFVVFLARVVGYFIDRTVFRNERGVGAGYFITVLVCEIIFGLLASIIVAWFSRQREYRADAGSAQLMGSREPMMRALARLGGLEPGELPKSFEASGIAGKGGLGAIFASHPPIQARIAALQHMRVV
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL32_ECOLC
Sequence: MAVQQNKPTRSKRGMRRSHDALTAVTSLSVDKTSGEKHLRHHITADGYYRGRKVIAK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: NADK_PSEAB
Sequence: MEPFRNIGIIGRLGSTQVLDTIRRLKKFLIDRHLHVILEDTIAEVLPGHGLQTCSRKIMGEICDLVVVVGGDGSMLGAARALARHKVPVLGINRGSLGFLTDIRPDELEAKVGEVLDGQYIVESRFLLDAQVRRGIDSMGQGDALNDVVLHPGKSTRMIEFELYIDGQFVCSQKADGLIVATPTGSTAYALSAGGPIMHPKLDAIVIVPMYPHMLSSRPIVVDGNSELKIVVSPNMQIYPQVSCDGQNHFTCAPGDTVTISKKPQKLRLIHPIDHNYYEICRTKLGWGSRLGGGD
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSN5_USTMA
Sequence: MTAPSSSSSASMARANFELNNAIIPLSSTTLDSIFAYDNEAQRAILHAQPWKTDPHFFQKVRISAVALIKMVMHARSGGIYEIMGLMQGKIDVENRTLYVMDSFALPVEGTETRVNAQNEAYEYMVQYLDHSKEVGRLENVVGWYHSHPGYGCWLSGIDVNTQRTNQQFQDPFVAIVIDPNRTISSGKVDIGAFRTFPEGYTSSSSIGGGDSEYQSIPLSKIEDFGVHANEYYPLEVEHFKSSLDGKLLDLLWNKYWQNTLSQSPLVSNRAYTTSQIRDLADKLAQTNAAVLNRNSVSSAPFTTTAGAASVRIGAGKDVAAETEQNSGGSAKDTPAGTAQDAAGLVKEFEQRSKMSAISRASNDAAKLASEANHGLLASQLKHTLFHNHTATPTPASASAPTPIRL
What is the function of this protein?
Catalytic Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes.
What are the official names of this protein?
COP9 signalosome complex subunit 5.
What is the protein family that this protein belongs to?
Belongs to the peptidase M67A family. CSN5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: STK38_PONAB
Sequence: MAMTGSTPCSSMSNHTKERVTMTKVTLENFYSNLIAQHEEREMRQKKLEKVMEEEGLKDEEKRLRRSAHARKETEFLRLKRTRLGLEDFESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQVGHIRAERDILVEADSLWVVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRTEFYRNLNHSLPSDFTFQNMNSKRKAETWKRNRRQLAFSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNWKETLTFPPEVPISEKAKDLILRFCCEWEHRIGAPGVEEIKSNSFFEGVDWEHIRERPAAISIEIKSIDDTSNFDEFPESDILKPTVATSNHPETDYKNKDWVFINYTYKRFEGLTARGAIPSYMKAAK
What is the function of this protein?
Negative regulator of MAP3K1/2 signaling.  Converts MAP3K2 from its phosphorylated form to its non-phosphorylated form and inhibits autophosphorylation of MAP3K2 (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase 38.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: RLMH_GLUDA
Sequence: MRLIAVGRMKDRVERDLFQRYAERLSPRLDLVEVAEGRGAPAEIKRREGQALLSALPDRAFAVALDEGGRAHDSLAFARVLERWLGLSRPVCFLVGGAEGLDGPVLARADDTLSLGPMTWPHMLIRGLLAEQLYRARAIASGHPYHRAGRPA
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPC2_CANLF
Sequence: MRLLVAAFLLLALGDLGPGGAVHFKDCGSAVGVIKELNVNPCPAQPCKLHKGQSYSVNVTFTSNIPSQSSKAVVHGIVLGVAVPFPIPEADGCKSGINCPIQKDKTYSYLNKLPVKNEYPSIKLVVQWMLLGDNNQHLFCWEIPVQIEG
What is the function of this protein?
Intracellular cholesterol transporter which acts in concert with NPC1 and plays an important role in the egress of cholesterol from the lysosomal compartment.  Unesterified cholesterol that has been released from LDLs in the lumen of the late endosomes/lysosomes is transferred by NPC2 to the cholesterol-binding pocket in the N-terminal domain of NPC1.  May bind and mobilize cholesterol that is associated with membranes.  NPC2 binds cholesterol with a 1:1 stoichiometry.  Can bind a variety of sterols, including lathosterol, desmosterol and the plant sterols stigmasterol and beta-sitosterol (By similarity).  The secreted form of NCP2 regulates biliary cholesterol secretion via stimulation of ABCG5/ABCG8-mediated cholesterol transport (By similarity).
What are the official names of this protein?
NPC intracellular cholesterol transporter 2, Epididymal secretory protein E1, cE1, Niemann Pick type C2 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the NPC2 family.
What are the subcellular locations of this protein?
Secreted. Endoplasmic reticulum. Lysosome. Note=Interaction with cell-surface M6PR mediates endocytosis and targeting to lysosomes.
Protein: FANCL_MOUSE
Sequence: MDEAEASLLRHFPLLLPQNREKTVYEGFISAQGSDFHLRIVLPKDLQLKKARLLCSLQLKNILNEYHQVVQQRMKHSPDLMSFMMELKMILEVALKNKQELCVQPPSCSFCKDLLTEIGAIGWDKLACVESSFSTIKLKADDASGRKHLITVKLKAKYPVEPPDCVVDFPVPFSVSWTPQSSLVDVYSQFLVALETLKVFWDVMDEIDEKTWVLEPEKPPRSATARRIALGKNVSIAIEVDPRHPTMLPEFCFLGADHVTKPLGMKLSGSIHLWDPENSLLQNLKDVLEIDFPARSILEESDFSMDCGICYARHLNGAIPDQVCNNPQCGQPFHEICLYEWLRGLSTSRQSFNVFFGDCPYCSKPITLKMSGRKP
What is the function of this protein?
Ubiquitin ligase protein that mediates monoubiquitination of FANCD2, a key step in the DNA damage pathway.  Also mediates monoubiquitination of FANCI.  May stimulate the ubiquitin release from UBE2W.  May be required for proper primordial germ cell proliferation in the embryonic stage, whereas it is probably not needed for spermatogonial proliferation after birth.
What are the official names of this protein?
E3 ubiquitin-protein ligase FANCL, Fanconi anemia group L protein homolog, Proliferation of germ cells protein, RING-type E3 ubiquitin transferase FANCL.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=In the nucleus, colocalizes with UBE2W.
Protein: CELF3_MOUSE
Sequence: MKEPDAIKLFVGQIPRHLEEKDLKPIFEQFGRIFELTVIKDKYTGLHKGCAFLTYCARDSALKAQSALHEQKTLPGMNRPIQVKPADSESRGDRKLFVGMLGKQQTDEDVRKMFEPFGTIDECTVLRGPDGTSKGCAFVKFQTHAEAQAAINTLHSSRTLPGASSSLVVKFADTEKERGLRRMQQVATQLGMFSPIALQFGAYSAYTQALMQQQAALVAAHSAYLSPMATMAAVQMQHMAAISANGLIATPITPSSGTSTPPAIAATPVSAIPAALGVNGYSPVPTQPTGQPAPDALYPNGVHPYPAQSPAAPVDPLQQAYAGMQHYTAAYPAAYSLVAPAFPQPPALVAQQPPPPPQQQQQQQQQQQQQQQQREGPDGCNIFIYHLPQEFTDSEILQMFVPFGHVISAKVFVDRATNQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDANRPY
What is the function of this protein?
RNA-binding protein involved in the regulation of pre-mRNA alternative splicing.  Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing.  Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition.  Activates the splicing of MAPT/Tau exon 10.  Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA (By similarity).
What are the official names of this protein?
CUGBP Elav-like family member 3, CELF-3, Bruno-like protein 1, CUG-BP- and ETR-3-like factor 3, ELAV-type RNA-binding protein 1, ETR-1, RNA-binding protein BRUNOL-1, Trinucleotide repeat-containing gene 4 protein.
What is the protein family that this protein belongs to?
Belongs to the CELF/BRUNOL family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: CP21C_ARATH
Sequence: MAKIKPQALLQQSKKKKGPSRISITNIVIYTLAVLLLVFVLFSAYRRWTHRSEIPTHNGRSVLEDAAFPGMKNVDLPRFATLDTGKGSVTIELFKDTAPNVVDQFMKFCQDGYFKGFLFSRVVKHFVIQAGDSAEFDAVKDWALDRKNIDTSLKHEEFMVGTPKAKNEQGGFEFFIVSAQIKDLNEKLTVFGRVSKGQDVVQEIEEVETDDQYQPKSPIEIMSVTLLQDM
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase CYP21-3, mitochondrial, PPIase CYP21-3, Cyclophilin of 21 kDa 3, Rotamase CYP21-3.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PROF5_HEVBR
Sequence: MSWQTYVDDHLMCDIDGHRLTAAAIIGHDGSVWAQSSGFPQFKSDEVAAVMKDFDEPGSLAPTGLHLGGTKYMVIQGEPGAVIRGKKGSGGITVKKTGQALIIGIYDEPLTPGQCNMIVERLGDYLLEQGM
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity).
What are the official names of this protein?
Profilin-5, Pollen allergen Hev b 8.0203.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RNPA_HELHP
Sequence: MARLDTLKNKAEFDFVYRNAQRFFHKDFVLYMLKFSSIRESYPLRQQRIFQSIQSRNAKLHLGLSVSRKIGKAYMRNLIKRRIKAIAYENCADFKDVIFLIVVKEGIREMDFATLKNNLLASFIKMYNAKKTRNIRVLHQISHYAG
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: HRCA_STRPM
Sequence: MITQRQNDILNLIVELFTQTHEPVGSKALQRTIDSSSATIRNDMAKLEKLGLLEKAHTSSGRMPSPAGFKYFVEHSLRLDSIDEQDIYHVIKTFDFEAFKLEDMLQKASHILAEMTGYTSVILDVEPARQRLTGFDVVQLSNHDALAVMTLDESKPVTVQFAIPRNFLTRDLIAFKAIVEERLLDSSVIDIHYKLRTEIPQIVQKYFVTTDNVLQLFDYVFSELFLETVFVAGKVNSLTYSDLSTYQFLDNEQQVAISLRQSLKEGEMASVQVADSQEAALADVSVLTHKFLIPYRGFGLLSLIGPIDMDYRRSVSLVNIIGKVLAAKLGDYYRYLNSNHYEVH
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: SYR_PSE14
Sequence: MKDTIRQLIQQALTRLVTEGVLPEGLTPAIQVENARDKTHGDFASNIAMMLAKPAGMKPRDLAEKLIAALPSDEQVSKVEIAGPGFLNFFQNTAALAARLDAALADAHLSVRKAGAVQRVVVDLSAPNLAKEMHVGHLRSTIIGDGVANVLTFLGDTVIRQNHVGDWGTQFGMLLAYLQEKPATSDELSDLENFYRAAKQRFDESEEFAERARGLVVKLQAGDAECLALWTRFKDISLSHCQETYERLNVKLTPADVMGESAYNDDLANVVNDLKATGLLVESNGAQCVFLEEFRTADDTPLPVIVQKAGGGYLYATTDLAAIRYRSKVLKADRVLYFVDQRQALHFQQVFEVARRAGFVHDGMQLEHMGFGTMNGADGRPFKTRDGGTVKLIDLLDEAEERAYTLVKEKNPEVAEAELRSIAKAVGISAVKYADLSKHRASDYSFNFDQMLSFEGNTAPYLLYAYTRVAGVFRKLGTPFDASKGQIVLAAPQEQELAARLAQFTETLNNVAEKGTPHVLCAYLYDLAGLFSSFYENCPILGAENPDQQQSRLRLAALTGRTLKQGLDLLGLETLERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLN1A_CLOSA
Sequence: MAKYTKEDIINLVKENGVKFIRLQFTDIFGTLKNVAITDKQLEKALDNECMFDGSSIDGFVRIEESDMNLRPNLDSFVIFPWRPQQGKVARLICDVYKPDGTPFEGDPRHVLKRANADAKELGYTMNVGPECEFFLFETDENGRATTNTQDKAGYFDLAPTDLGENARRDMTLALEEMGFEIEASHHEVAEGQNEIDFKYGDALTTADNIMTFKLVVKSIAQRHGLHASFMPKPIFGINGSGMHVNMSLFKDGKNAFVDENDKNGLSKVAYQFIAGLLKNIKGMAAVTNPLVNSYKRLVPGYEAPVYLAWSCKNRTALIRVPAARGAGTRVELRCPDPSSNPYLVLACLLQAGLDGIKNNLQPPAEVEANIFAMTEQERKENGIDNLPNNLYEAVNYMKENELAKKALGDHVYGNYVAGKAAEWDDYRTKVHDWELENYLNKY
What is the function of this protein?
Glutamine synthetase (GS) is an unusual multitasking protein that functions as an enzyme, a transcription coregulator, and a chaperone in ammonium assimilation and in the regulation of genes involved in nitrogen metabolism.  It catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.  Feedback-inhibited GlnA also interacts with and regulates the activity of the transcriptional regulator TnrA.  During nitrogen limitation, TnrA is in its DNA-binding active state and turns on the transcription of genes required for nitrogen assimilation.  Under conditions of nitrogen excess, feedback-inhibited GlnA forms a stable complex with TnrA, which inhibits its DNA-binding activity.  In contrast, feedback-inhibited GlnA acts as a chaperone to stabilize the DNA-binding activity of GlnR, which represses the transcription of nitrogen assimilation genes.
What are the official names of this protein?
Glutamine synthetase, GS, Glutamate--ammonia ligase, Glutamine synthetase I alpha, GSI alpha.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NVD_BOMMO
Sequence: MADRQHFPSAITEAVSSNTACPDTGPKAETTNIFLLLQRNITIESSKHVFSSIVEYILILTLMFAFSAILYVIYKSYISPVFYKKELTEVGFDHIPQGPDKGRRISRAQASRRMGSKLPPPYPNGWFAVAETRELKVGSVLSIDALGQNLCVYRGEDGLARCVDAYCPHLGANLAVGGTVRGSCIECPFHKWRFNAAGTCVSLPGSDIAPKGVSIRTWCVVETDGAIWIWHDAEGREPLWEITDPPELKDFGYRGRNEFEVSAHIQEIPENGADVPHLNAVHSSSLLSDLGERYPVLHEIIGRHVWNADWTKSDDHTSLMHITQEYKVLKYDLARIDVKVTQIGPGHVRLFLKTSVGPFYIAQSVTPLGPLLQKVIHRVYSPAYNAPVGAFLVRCEAYMFERDVTIWNSKRFVSAPAYVKTDKTIRTFRNWFGQFYSEHSLSFRDALQNPLDW
What is the function of this protein?
Catalyzes the production of 7-dehydrocholesterol (7-DHC or cholesta-5,7-dien-3beta-ol) by inserting a double bond (desaturating) at the C7-C8 single bond of cholesterol.  Essential regulator of steroid biosynthesis as this reaction is the first step in the synthesis of the steroid hormone Delta(7)-dafachronic acid.
What are the official names of this protein?
Cholesterol 7-desaturase nvd, Neverland, Nvd_Bm, Rieske-domain protein Neverland.
What is the protein family that this protein belongs to?
Belongs to the cholesterol 7-desaturase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RS13_MYCMM
Sequence: MARLVGVDLPRDKRMEIALTYIYGVGRTRSNEILAATGIDRNLRTRDLTDDQLTHLRDYIEANLKIEGDLRREVQADIRRKIEIGCYQGLRHRRGLPVRGQRTKTNARTRKGPKRTIAGKKKAR
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: TRPC_ACIBY
Sequence: MINIQNTILGKIVDRKHEELAARLKQRNLQDVEELAKAATPVRGFANALQHKRPGVIAEIKKASPSKGIIRADFNPAEIAQQYEQAGAACLSVLTDVDFFQGADENIAIARNHCALPALRKDFLVDPYNVVEARALHADCILLIVACLSDQQLEEMSKTAFEHQLDVLVEVHDEEELERALKLSEQCLLGVNNRNLKTFDVDLNTTIRLKKLLPASRLLITESGIATPDDVRMMQEHDIHSFLVGESFMKQPRPDQAFTALFGQPQTV
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: UP02_PSEMZ
Sequence: FTLTNSDVLE
What are the official names of this protein?
Unknown protein 2.
Protein: RL11_GEOUR
Sequence: MAKKITGYIKLQIPAGKANPSPPIGPALGQHGVNIMEFCKAFNAKTQAEEGTITPVVITVFADRSFSFITKTPPASVLIKKALGIESGSSVPNKNKVGKLTKDQVKEIAAKKMPDLNAASLETAMKTIEGTARSMGVEIV
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RS8E_METM5
Sequence: MAIWQGASRRLSTGAKVWRAAKKHKREMGRPAAETQVSEVIKRKIVRCRGANLKVKLEKTNYANVFDQANNVCKKVAVTKVLDNKANKHYIRRNVMTKGAIIETEMGKAKVTSRPGQDGVVNAVLITE
What are the official names of this protein?
30S ribosomal protein S8e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS8 family.
Protein: COAD_AFIC5
Sequence: MAHVALYPGSFDPVTNGHVDVVRQACTLVDRLIVAIGVHPGKAPLFSVDERRAMIVEVFSPLAATTGCAIECVTFDNLTVAAAEKSGATILIRGLRDGTDLDYEMQIAGMNQTLVPSVQTIFIPASPTVRPITATLVRQIASMGGDVSAFVPKAVAARLKAKFSQ
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDI_MYCTA
Sequence: MDIAGRSLVYFSSVSENTHRFVQKLGIPATRIPLHGRIEVDEPYVLILPTYGGGRANPGLDAGGYVPKQVIAFLNNDHNRAQLRGVIAAGNTNFGAEFCYAGDVVSRKCSVPYLYRFELMGTEDDVAAVRTGLAEFWKEQTCHQPSLQSL
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: PLPL_NEUCR
Sequence: MADDTDNPPNIQIPAKSYGFPPEAFDPRRLPDYDTNFLPAHDLEAFIQALAAPDFVQSPDDASSMRLNSPGLHSPSSLDITKDDYDHSEARAALASVADVAAPGGGNNHHRRTSTGTFFSAHNDWAPVSEKVIKTDRDEKRNKRGKDRKNKKPRKGVAPLRTLVGTRSKDETREGYLYSLLKWPFLLFVSFWIVGLGMAYLATRFYIYFYEQFVAWRGRREQLRRAMRATGNYKDWVAAARNMDDFFGNQRWKEENDFAYYDSKTVRRVWDQMRRCREKAEEVERELESQSQNSDSGVASGEETSNTKAGGGNNGNDKKTQPVEDLKALIEACVKNNFVGIENPRLYSQTYYGTKNLVQNYVDEVERSIKFLIDTKQLTKEQKRVMFKGICANYGRTALCLSGGATFAYYHFGVVKALLEVDYLPDIITGTSGGALVAALVATRTNDELKELLNPALAHKITACRESFTVWFWRWWKTGARFDSVDWAKQCAWWCHGSLTFREAYERTGRILNVSCVPSDPHSPTILCNYLTSPDCVIWSAVLASAAVPGILNPVVLMMKNRDGSLEPYSFGHKWKDGSLRTDIPIKSLNLHFNVNFSIVSQVNPHINLFFFSSRGSVGQPVTHRKGRGWRGGYLGSATEQYIKLDLTKWLRVLRQLELLPRPLGQDWSQLWLQTFGGTVTIWPKSIPSDFLKILSDPDPPRLARMIHEGQQSAFPKVKFIANRLKIERLVERGRRETRDRRNAANAFTATGDGEGSYASHSIVDAMGGKHPLAPSSSGGAGDRRGSIESILSEDDLRSLLIKGREGVHTSGGSSTGTEDELTMTELEGEDDDGGTSRVSEGGSRNRYFEGALEEEDGALEVAASDHSRT
What is the function of this protein?
Probable lipid hydrolase.
What are the official names of this protein?
Patatin-like phospholipase domain-containing protein NCU11180.
What is the protein family that this protein belongs to?
Belongs to the PLPL family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RS16_SALPK
Sequence: MVTIRLARHGAKKRPFYQVVVTDSRNARNGRFIERVGFFNPIASEKEEGTRLDLDRIAHWVGQGATISDRVAALIKEVKKAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: PNTX_XIBTU
Sequence: MKEANTRRYIHLCLVVVLVSTIITTEAEDDRLFCIRHHKYCGHRPNRCCSGLFCRCNTFGTNCRCQSKGALGKLISGK
What is the function of this protein?
Probable neurotoxin.  May act as a ion channel modulator that causes the immobilization of prey.  This primitively aquatic arthropod may feed on crustaceans (or other arthropods), since its venom contains many chitinases.
What are the official names of this protein?
Putative neurotoxin.
What are the subcellular locations of this protein?
Secreted.