PharMolix/UniProtQA huggingface dataset:
Protein: TRAIP_MOUSE
Sequence: MPIRALCTICSDFFDHSRDVAAIHCGHTFHLQCLIQWFETAPSRTCPQCRIQVGKKTIINKLFFDLAQEEENVLDAEFLKNELDSVKAQLSQKDREKRDSQAIIDTLRDTLEERNATVESLQNALNKAEMLCSTLKKQMKFLEQRQDETKQAREEAHRLKCKMKTMEQIELLLQSQRSEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYENLKEARKATGELADRLKKDLVSSRSKLKTLNTELDQAKLELRSAQKDLQSADQEITSLRKKLMILQGTLSLPPATNETVSRLVFESPAPVEMMNPRLHQPPFGDEIDLNTTFDVNTPPTQTSGSQHCLPKKLCLERARSPMQNVLKKVHKVSKPESQLSLGGQRCVGELDEELAGAFPLFIRNAVLGQKQPNRTTAESRCSTDVVRIGFDGLGGRTKFIQPRDTTIIRPVPVKSKAKSKQKVRIKTVSSASQPKLDTFLCQ
What is the function of this protein?
E3 ubiquitin ligase required to protect genome stability in response to replication stress (PubMed:33590678).  Acts as a key regulator of interstrand cross-link repair, which takes place when both strands of duplex DNA are covalently tethered together, thereby blocking replication and transcription (By similarity).  During mitosis, controls the choice between the two pathways of replication-coupled interstrand-cross-link repair by mediating ubiquitination of MCM7 subunit of the CMG helicase complex (PubMed:33590678).  Short ubiquitin chains on MCM7 promote recruitment of DNA glycosylase NEIL3 (By similarity).  If the interstrand cross-link cannot be cleaved by NEIL3, the ubiquitin chains continue to grow on MCM7, promoting the unloading of the CMG helicase complex by the VCP/p97 ATPase, enabling the Fanconi anemia DNA repair pathway (By similarity).  Only catalyzes ubiquitination of MCM7 when forks converge (By similarity).  Also involved in the repair of covalent DNA-protein cross-links (DPCs) during DNA synthesis: promotes ubiquitination of DPCs, leading to their degradation by the proteasome (By similarity).  Has also been proposed to play a role in promoting translesion synthesis by mediating the assembly of 'Lys-63'-linked poly-ubiquitin chains on the Y-family polymerase POLN in order to facilitate bypass of DNA lesions and preserve genomic integrity (By similarity).  The function in translesion synthesis is however controversial (By similarity).  Acts as a regulator of the spindle assembly checkpoint (By similarity).  Also acts as a negative regulator of innate immune signaling by inhibiting activation of NF-kappa-B mediated by TNF (PubMed:17544371, PubMed:22945920).  Negatively regulates TLR3/4- and RIG-I-mediated IRF3 activation and subsequent IFNB1 production and cellular antiviral response by promoting 'Lys-48'-linked polyubiquitination of TNK1 leading to its proteasomal degradation (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase TRAIP, TRAF-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the TRAIP family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus, nucleolus. Chromosome. Cytoplasm. Cytoplasm, perinuclear region. Note=In the nucleus, found in close proximity to PCNA, suggesting localization at replication foci. Localizes to DNA damage sites in response to replication stress.
Protein: ABRX2_MOUSE
Sequence: MAASISGYTFSAVCFHSANSNADHEGFLLGEVRQEETFSISDSQISNTEFLQVIEIHNHQPCSQLFSFYDYASKVNEESLDRILKDRRKKVIGWYRFRRNTQQQMSYREQVIHKQLTRILGVPDLVFLLFSFISTANNSTHALEYVLFRPNRRYNQRISLAIPNLGNTSQQEYKVSSVPNTSQSYAKVIKEHGTDFFDKDGVMKDIRAIYQVYNALQEKVQAVCADVEKSERVVESCQAEVNKLRRQITQKKNEKEQERRLQQALLSRQMPSESLEPAFSPRMSYSGFSAEGRSTLAETEPSDPPPPYSDFHPNNQESTLSHSRMERSVFMPRPQAVGSSSYASTSGGLKFTGSGADLLPSQSAAGDSGEESDDSDYENLIDPAESPHSEYSHSKNSRPSTHPDEDPRNTQTSQI
What is the function of this protein?
Component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked polyubiquitin, leaving the last ubiquitin chain attached to its substrates.  May act as a central scaffold protein that assembles the various components of the BRISC complex and retains them in the cytoplasm (By similarity).  Plays a role in regulating the onset of apoptosis via its role in modulating 'Lys-63'-linked ubiquitination of target proteins (PubMed:21195082).  Required for normal mitotic spindle assembly and microtubule attachment to kinetochores via its role in deubiquitinating NUMA1.  Plays a role in interferon signaling via its role in the deubiquitination of the interferon receptor IFNAR1; deubiquitination increases IFNAR1 activities by enhancing its stability and cell surface expression (PubMed:24075985, PubMed:26344097).  Down-regulates the response to bacterial lipopolysaccharide (LPS) via its role in IFNAR1 deubiquitination (PubMed:24075985).  Required for normal induction of p53/TP53 in response to DNA damage.  Independent of the BRISC complex, promotes interaction between USP7 and p53/TP53, and thereby promotes deubiquitination of p53/TP53, preventing its degradation and resulting in increased p53/TP53-mediated transcription regulation and p53/TP53-dependent apoptosis in response to DNA damage (By similarity).
What are the official names of this protein?
BRISC complex subunit Abraxas 2, Abraxas brother protein 1, Protein FAM175B.
What is the protein family that this protein belongs to?
Belongs to the FAM175 family. Abro1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton. Note=A minor proportion is detected in the nucleus. Translocates into the nucleus in response to DNA damage. Directly binds to microtubules and is detected at the minus end of K- fibers. Co-localizes with NUMA1 at mitotic spindle poles.
Protein: PEPC_LACLA
Sequence: MTVTSDFTQKLYENFAENTKLRAVENAVTKNGLLSSLEVRGSHAANLPEFSIDLTKDPVTNQKQSGRCWMFAALNTFRHKFINEFKTEDFEFSQAYTFFWDKYEKSNWFMEQIIGDIEMDDRRLKFLLQTPQQDGGQWDMMVAIFEKYGIVPKAVYPESQASSSSRELNQYLNKLLRQDAEILRYTIEQGGDVEAVKEELLQEVFNFLAVTLGLPPQNFEFAFRNKDNEYKKFVGSPKEFYNEYVGIDLNNYVSVINAPTADKPYNKSYTVEFLGNVVGGKEVKHLNVEMDRFKKLAIAQMQAGETVWFGCDVGQESNRSAGLLTMDSYDFKSSLDIEFTQSKAGRLDYGESLMTHAMVLAGVDLDADGNSTKWKVENSWGKDAGQKGYFVASDEWMDEYTYQIVVRKDLLTEEELAAYEEKPQVLLPWDPMGALA
What is the function of this protein?
Hydrolyzes naphthylamide-substituted amino acids as well as di- and tripeptides in which the half-cystine residue is involved in a disulfide loop, notably in oxytocin and vasopressin.  Has also a bleomycin hydrolase activity (By similarity).
What are the official names of this protein?
Aminopeptidase C, Bleomycin hydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
Protein: ATPG_KLEP3
Sequence: MAGAKEIRSKIASVQNTQKITKAMEMVAASKMRKSQERMAASRPYADTMRKVIGHLANGNLEYKHPYLEERDVKRVGYLVVSTDRGLCGGLNINLFKKLLAEMKAWSDKGVQCDLAMIGSKGVSFFNAVGGNVVAQVTGMGDNPSLSELIGPVKVMLQAYDEGRLDKLYVVSNKFINTMSQVPTITQLLPLPASEDADLKRKSWDYLYEPDPKALLDTLLRRYVESQVYQGVVENLASEQAARMVAMKAATDNGGSLIKELQLVYNKARQASITQELTEIVGGASAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PSLS_METTH
Sequence: MNAFDFLTPPRSGKPRKNGITMVLDKGMGPASARDLMEISSDYVDFIKFGWGTLPLHRRDTVKEKVDMYRSFDVEPYPGGTLFEIAHLNDKVEEYFQEARSLGFETLEISNGTVEIETEEKCRLIEMAVDEGFMVLSEVGKKDPERDRLLEPDDRVRLVRADLRAGASMVLMEARESGQNIGIYDERGNIREDEFNHLTDRLPMDRIIWEAPQKSQQVYFILKIGPDVNLGNIPPEEITALETIRRGLRGDTLGKVNL
What is the function of this protein?
Catalyzes the addition of sulfite to phosphoenolpyruvate (PEP) to yield (2R)-phospho-3-sulfolactate (PSL).
What are the official names of this protein?
Phosphosulfolactate synthase, (2R)-phospho-3-sulfolactate synthase, PSL synthase.
What is the protein family that this protein belongs to?
Belongs to the phosphosulfolactate synthase family.
Protein: SYY_CORGL
Sequence: MNIIDELSWRGLINQSTDLEALREEASTPITLYCGFDPTGPSLHAGHLVPLLMLRRFQQAGHNPIVLAGGATGMIGDPRDVGERTMNSADTVSDWAERISGQLSRFVDFDGEHAARLVNNAEWTNEMSVVTFLRDVGKHFSLNTMLARDTVKRRLESDGISYTEFSYMLLQANDYVELNKRFGCTLQVGGGDQWGNIVSGVDLNRRVNGTSVHAVTVPLVTDSDGKKFGKSTGGGSLWLDPEMTSPYAWYQYFINASDADVIRYLRWFTFLTQEELAELEVEVAERPFKREAQRRLAREMTNLVHGTEATEAVELAAQALFGRAELRDLDEKTLAASVSETAVAEIKAGEPRTIIDLLVASGLADSKGAAKRAVKEGGAYVNNERIESDDWEPFAEDLLHGSWLVLRRGKKNFAGVQILG
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMB_RHORT
Sequence: MPEKPTEDARFYGRRKGKPLRATRQRLLDTMLPALTLPLAGLGEGERLDPRGLFPRPVDQLWLEIGFGGGEHLVAQAAAHPEVGLIGSEVFAYGVGKALSQIDETGVDNIRLWPEDVRQVLPALPDGCLQRLFVLFPDPWPKRRHARRRMIQPARLDDFARLLADGGELRVASDDMGYVRWTLMHVTAHPAFRWTAQGPTDWRERPADWVETRYEAKALQAGRKPAYLIFRRRPRAADPGTLAEAPAGEGADNNP
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: OMCB_CHLAB
Sequence: MSKLIRRVVTVLALTSMASSFASGKIEAAAAESLATRFIASTENSNDNVLQATAKKVRFGRNKNQRQEQKHTGAFCDKEFYPCEGGQCQSVDTTQESCYGKMYCVRVNDDCNVEISQAVPEYATVGSPYPIEILAVGKKDCVNVVITQQLPCEVEFVSSDPATTPTSDSKLIWTIDCLGQGEKCKITVWVKPLKEGCCFTAATVCACPELRSYTKCGQPAICIKQEGPECACLRCPVCYKIEVCNTGSAIARNVVVDNPVPDGYTHASGQRVLSFNLGDMRPGDSKCFSVEFCPQKRGKITNVATVSYCGGHKCSANVTTVVNEPCVQVNISGADWSYVCKPVEYTIVVSNLGDLKLYDVVVEDTVPSGATILEAEGAEICCNKAVWCIKEMCPGETLQFKVVAKAQSPGKFTNQVVVKTNSDCGTCTSCAEATTHWKGLAATHMCVIDTNDPICVGENTVYRICVTNRGSAEDTNVSLILKFSKELQPVSSSGPTKGTITGNTVVFDALPKLGSKESVEFSVTLKGIAPGDARGEAILSSDTLTVPVADTENTHVY
What is the function of this protein?
In elementary bodies (EBs, the infectious stage, which is able to survive outside the host cell) provides the structural integrity of the outer envelope through disulfide cross-links with the small cysteine-rich protein and the major outer membrane porin.  It has been described in publications as the Sarkosyl-insoluble COMC (Chlamydia outer membrane complex), and serves as the functional equivalent of peptidoglycan.  It is present but the disulfide bonds are reduced in reticulate bodies (RBs) (By similarity).
What are the official names of this protein?
Large cysteine-rich periplasmic protein OmcB, Large-CRP, 60 kDa CRP, 60 kDa outer membrane protein, Cysteine-rich outer membrane protein.
What are the subcellular locations of this protein?
Periplasm.
Protein: TM256_MOUSE
Sequence: MAGVGAAFRRLGALSGAGALGLASYGAHGAQFPDAYGKELFDKANKHHFLHSLALLGVPSCRKPVWAGLLLASGTTLFCTSFYYQALSGDTSIQTLGPVGGSLLILGWLALAF
What are the official names of this protein?
Transmembrane protein 256.
What is the protein family that this protein belongs to?
Belongs to the TMEM256 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS14_STRPQ
Sequence: MAKKSKIAKYQKQLQLIEQYADLRRDLKAKGDYESLRKLPRDSNPNRLKNRDKIDGRPHAYMRKFGVSRINFRDLAHKGQLPGVTKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: AMTAB_ARCFU
Sequence: MRVAIETYGCTTNQADSDIMRGFLSGEFELSSVEDAEVVIINSCGVIDFTERKIIRRMLDLKREGKKVVLAGCLTRISKEALSVADSALSPDNLDMVVDAVYSALNGRKLFTERRFIDKAEFSHLKCRLRENAIAIVSISEGCLGKCSFCATKFARGRLRSFSMDAIVREAERAVRAGYREIQLTSQDTGAYGMDKGRAMLPELLRKISEIEGEFRVRVGMMNPQHAVRMLDELINAYSSEKIYKFLHIPVQSGDNRILEDMKRNHTVEDYVEVVEAFRNSFDDVLISTDIIVGFPTETEEAFWKSYELIKETRPDIVNITRYSARKGTPAARLRDIPGWIKKERSRKLTDLMRKIGLENNKRFVGKKLRVLVTKEGKNGRNLARMNSYRAVVTEGAVGEFVEVKIKDCRFNYLIGQLAAEQPQ
What is the function of this protein?
Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
What are the official names of this protein?
Probable threonylcarbamoyladenosine tRNA methylthiotransferase, tRNA-t(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. CDKAL1 subfamily.
Protein: AGUA_PECAS
Sequence: MMSQLAAPHVTTPHQDGFAMPAEWAPHDAVWMIWPYRTDNWREQGVPAQKTFARVAEAIAQNTPVIMGVPARYMADAQKVMPVNVTLVEMESDDAWMRDTGPTIVLNQAGERRGIDWQFNAWGGELGGLYEDWRQDEKVAAQVLDYHQAAGYAAPLILEGGSIHVDGEGTLLTTAECLLNPNRNPHLSKAEIEQLMRDYLSISTIIWLEEGVYNDETDGHIDNMCCFVRPGEVALHWTDDENDPQYARSVAAYEVLSAARDAQGRELKIWKLPAPGPLHATKEEAQGVDSGDAVERLAGSRLAGSYVNFLISNQQIIFPLLDEKTDDVARDLLQQMFPDYLISGVPAREILLGGGNIHCITQQIPTAK
What are the official names of this protein?
Putative agmatine deiminase, Agmatine iminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the agmatine deiminase family.
Protein: ATPZ_PROMO
Sequence: MNQEIKKILKNSLITSLIVLVYGIVVRNPIVYFGMFVGCLISTFCFYMICQEAESAMKSGSPFKMTVTGYMKRYAIYGIYLGILVKFFGFPVFLGGAVGLLNIKFNIFLKVVSTQFEKIKKKLSSLK
What is the function of this protein?
A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex.
What are the official names of this protein?
ATP synthase protein I, sodium ion specific.
What is the protein family that this protein belongs to?
Belongs to the bacterial AtpI family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RIMM_AMOA5
Sequence: MNKNCVEVGKITQARGLKGCVVARIEPILESFDPINYIFIKIGHTLVPYQVEEITGQAQQVFIKFQHISDRDSVRELIGSSIWLSQEILDKLVVQEEPYIDIIGYQVTDKYQGELGIIKDIEQFPLHVCLVVDYLDKELLIPYEPALIQDLDHEQKKIIVELPMGFLEAMGCK
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SBCD_STAHJ
Sequence: MKVIHTADWHLGKILNGKQFLEDQHYILNKLIDNLKEEKPDVLVISGDIYDTSYPSKETIRLFEETIKIINVNMKIPTIITNGNHDGRERLNYGSTWFEFSQLYIRTQLELMSTPITINNINFYTLPFATISEIKAYFDDDDIKTYEQATQKCINHISKIIDPNQINILIGHLTIKGGKTSESERPLTIGTVESVESANFNIFDKVLLGHLHHPFSITDNIVDYSGSLLQYSFSEVNQAKGYKKLMINSKGDINTKFVQLKPLRELEEIEGDYSAVIQGDVPVKNKDNYFHFKLKNMSHVTDPIIHLKQIYPNTLSLSNITFENHNKSTYADFKTTDDPTIIKNFYKTITDEDLTNYQEKKIHQLLNQVINRED
What is the function of this protein?
SbcCD cleaves DNA hairpin structures.  These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions.  The complex acts as a 3'->5' double strand exonuclease that can open hairpins.  It also has a 5' single-strand endonuclease activity (By similarity).
What are the official names of this protein?
Nuclease SbcCD subunit D.
What is the protein family that this protein belongs to?
Belongs to the SbcD family.
Protein: APCB_ANASL
Sequence: MAQDAITAV
What is the function of this protein?
Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex.  Allophycocyanin has a maximum absorption at approximately 650 to 653 nanometers.
What are the official names of this protein?
Allophycocyanin beta chain.
What is the protein family that this protein belongs to?
Belongs to the phycobiliprotein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=Forms the core of the phycobilisome.
Protein: ARY1_BOVIN
Sequence: MDIDAYFERIGYKNSRDKLDLETLTDILQHQIRAIPFENLNIHCGEAMELDLEVIFDQIVRRKRGGWCLQVNHLLYWALTMIGFETTILGGYVYNTFNDKYSSAMIHLLLKVTIDGRDYIADAGFGRSYQMWQPLELISGKYQPQTPCIFRLTEDRGTWYLDQIRREQYIPNQDFLDSDLLEKNEYRKIYSFTLEPRTIKDFESVNTYLQESPASVFTSKSFCSLQTPEGVHCLVGFTLTYRRFNYKDNTDLVEFKTLNEKEIEENLKNIFNISLEKKLTPKHGDKFFTI
What is the function of this protein?
Participates in the detoxification of a plethora of hydrazine and arylamine drugs.
What are the official names of this protein?
Arylamine N-acetyltransferase 1, Arylamide acetylase 1, N-acetyltransferase type 1, NAT-1.
What is the protein family that this protein belongs to?
Belongs to the arylamine N-acetyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOLB_HAEIN
Sequence: MQPDSYPKILFGLTLLLVITAVISLGIGRYSLSVPQIGQILWAKATALEIDPVQQQVIFQVRLPRILTALCVGAGLALSGVVLQGIFRNPLVNPHIIGVTSGSAFGGTLAIFFGFSLYGLFTSTILFGFGTLALVFLFSFKFNQRSLLMLILIGMILSGLFSALVSLLQYISDTEEKLPSIVFWLMGSFATSNWEKLLFFFVPFLLCSSILLSLSWRLNLLSLDEKEAKALGVKMAPLRWLVIFLSGSLVACQVAISGSIGWVGLIIPHLSRMLVGANHQSLLPCTMLVGATYMLLVDNVARSLSDAEIPISILTALIGAPLFGVLVYKLKRGGMNE
What is the function of this protein?
Part of the ABC transporter complex MolBCA involved in molybdate import (PubMed:22078568, PubMed:24722984).  Responsible for the translocation of the substrate across the membrane (PubMed:24722984).  Functions as a low-affinity molybdate transporter (PubMed:24722984).
What are the official names of this protein?
Molybdate import system permease protein MolB.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LIPN_MYCTU
Sequence: MTKSLPGVADLRLGANHPRMWTRRVQGTVVNVGVKVLPWIPTPAKRILSAGRSVIIDGNTLDPTLQLMLSTSRIFGVDGLAVDDDIVASRAHMRAICEAMPGPQIHVDVTDLSIPGPAGEIPARHYRPSGGGATPLLVFYHGGGWTLGDLDTHDALCRLTCRDADIQVLSIDYRLAPEHPAPAAVEDAYAAFVWAHEHASDEFGALPGRVAVGGDSAGGNLSAVVCQLARDKARYEGGPTPVLQWLLYPRTDFTAQTRSMGLFGNGFLLTKRDIDWFHTQYLRDSDVDPADPRLSPLLAESLSGLAPALIAVAGFDPLRDEGESYAKALRAAGTAVDLRYLGSLTHGFLNLFQLGGGSAAGTNELISALRAHLSRV
What is the function of this protein?
Non specific carboxylic ester hydrolase.  Hydrolyzes various pNP-esters, with a preference for short carbon chain substrates.  Can also hydrolyze tributyrin to di- and monobutyrin and 4-hydroxyphenylacetate to hydroquinone.
What are the official names of this protein?
Carboxylic ester hydrolase LipN.
What is the protein family that this protein belongs to?
Belongs to the 'GDXG' lipolytic enzyme family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYST_MARPO
Sequence: MIPLFFIPPFIILFITKGKFRFLTKFELVLACALHYGTFILALPIFFLLYKTKQQPWNILLQTALEPVVLSAYGFTFLTALLATIINAIFGLILAWVLVRYEFPGKKLLDATVDLPFALPTSVGGLTLMTVFNDKGWIKPICSWLNIKIVFNPIGVLLAMIFVSLPFVVRTIQPVLQNMEEDLEEAAWCLGASPWTTFWHILFPPLTPSLLTGTTLGFSRALGEYGSIVLIASNIPMKDLVISVLLFQKLEQYDYKSATIIASFVLIISFTALFFINKIQLWKKTFHK
What is the function of this protein?
Part of the ABC transporter complex cysAWTP (TC 3. A. 1. 6. 1) involved in sulfate/thiosulfate import.  Probably responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
Probable sulfate transport system permease protein cysT.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: RS9_STRM5
Sequence: MAITQNYGTGRRKSSTARVFLRKGSGNITVNGRPLDEFFGRETARMIVRQPLELTKNTESFDILVTAAGGGTTGQAGAIRLGIARALVEYDETLKSELRKAGFMTRDAREVERKKVGLHKARRATQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: ARGO_ECO57
Sequence: MFSYYFQGLALGAAMILPLGPQNAFVMNQGIRRQYHIMIALLCAISDLVLICAGIFGGSALLMQSPWLLALVTWGGVVFLLWYGFGAFKTAMSSNIELASAEVLKQGRWKIIATMLAVTWLNPHVYLDTFVVLGSLGGQLDVEPKRWFALGTISASFLWFFGLAILAAWLAPRLRTAKSQRIINLVVGCVMWFIALQLARDGIAHAQALFS
What is the function of this protein?
Involved in the export of arginine.  Important to control the intracellular level of arginine and the correct balance between arginine and lysine.
What are the official names of this protein?
Arginine exporter protein ArgO.
What is the protein family that this protein belongs to?
Belongs to the LysE/ArgO transporter (TC 2.A.75) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPA_XANP2
Sequence: MDIRAAEITAILKEQIQNFGQEAEVSEVGQVLSVGDGIARVYGLDNVQAGEMVEFENGTRGMALNLEIDNVGIVIFGSDREIKEGQTVKRTRAIVDAPVGKGLLGRVVDALGNPIDGKGPIVYTERRRVDVKAPGIIPRKSVHEPMQTGLKAIDALIPIGRGQRELIIGDRQTGKTAVALDSILNQKPINQGTDEKAKLYCVYVAVGQKRSTVAQFVKVLEEQGALEYSIVVAATASDAAPMQFLAPFTGTAMGEYFRDNGMHALIIHDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDSLGAGSLTALPVIETQANDVSAYIPTNVISITDGQIFLESDLFYQGIRPAVNVGLSVSRVGSSAQIKAMKQVAGKIKGELAQYRELAAFAQFGSDLDASTQKLLNRGARLTELLKQSQFSPLKVEEQVAVIFAGTNGYLDPLPVSKVREFEQGLLLALRSQHPEILEAIRSSKEISKDTTEKLTKALDAFAKSFA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DCUP_ECO27
Sequence: MTELKNDRYLRALLRQPVDVTPVWMMRQAGRYLPEYKATRAQAGDFMSLCKNAELACEVTLQPLRRYPLDAAILFSDILTVPDAMGLGLYFEAGEGPRFTSPVTCKADVDKLPIPDPEDELGYVMNAVRTIRRELKGEVPLIGFSGSPWTLATYMVEGGSSKAFTVIKKMMYADPQALHALLDKLAKSVTLYLNAQIKAGAQAVMIFDTWGGVLTGRDYQQFSLYYMHKIVDGLLRENDGRRVPVTLFTKGGGQWLEAMAETGCDALGLDWTTDIADARRRVGNKVALQGNMDPSMLYAPPARIEEEVASILAGFGHGEGHVFNLGHGIHQDVPPEHAGVFVEAVHRLSEQYHR
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_ECO45
Sequence: MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: Y2135_AERHH
Sequence: MLCAVYKSRKKAETYLFVERREDFSRVPEVLMSAFGRPELVLMTKLDPAKPLGIASTSRVMEALQSQGFYLQVPPPPENLLEQHKAQLKAERE
What are the official names of this protein?
YcgL domain-containing protein AHA_2135.