PharMolix/UniProtQA huggingface dataset:
Protein: LIPA_MYCPU
Sequence: MNKKYFKKYSWVLILSTSILAPMTLASCNHNVAKKEDKTQNDSSNLSNKTNKSDPNDHLKDKDKNVSQDNKDSTNKAVSNENSQTQSQKTNESSQNTKDDSSKTSNLITNQNSSSNTKSKIQENKQSQKDQNTSAVNVSALEKQTKNDENISLVNSKDTNVILKNDEKVALAKDDSKEKSKNSSNLNLKTPVENRQNKNEVKDDKKALQWWQKLNESASILESFSYDQTSLSLTFKEGMPLGLEVVLKLENLDSHEEKEISFKTTNGKVQNVLLTSSNLTSGKWKIKSFSFDKTYSHSPTIETTFDFKTNEKLKQERIEKIQKAIDKYQIKIKQNYKDKPLISKYALSNFDLNLNFKDLEIVNNSLKFDGSNLNQDLKSEKQMKITFEKVSENQANKTRKAHFKITTLDNLVFEKTLEWSYKTNKEYLDEFKNGSALWDDLQASLTSVFEKSLWHPYQLPKAKSKINTINLINDVSASFQGYDYLDDFNGSAKLKFKLQRGQEQRDITFTINGFLKVSLIDPLYKGNLRNSEFDVKASSNGYWLGQYYTAAEVFKHYSNGKSYWYATANDGNPWLEFS
What are the official names of this protein?
Lipoprotein A.
What is the protein family that this protein belongs to?
Belongs to the M.pulmonis LipAB lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: Y1883_LACH4
Sequence: MKIIIAPAKIMKIDRDSFPVQSKPEFLDKTRILEEFLKSRSEDQLIELWHASKKVTEQSIEQLKNMNLDKRLTPAILAFSGIQYQYMAPDLFTQPALDYIQKNLRILSGFYGMLRPFDGVCPYRLELNTKMKGFIDYSLYHFWNDQIAESLFKEDDTVINLASKQYMRLVKPYLNENRKMITIDFQELKNDQWKTVGVHAKMARGEMVRFIAENQMKNPAELRDFHDFEFQYSPEASSLDHYVFRTHFDFKRH
What are the official names of this protein?
UPF0246 protein lhv_1883.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: 2B_TRVTC
Sequence: MGNGDWSSKWPNDHLFIDDFGKLVWFDVLTDIVKISHFVSQVPTDLSPIPSSYISFIDGRIPMCINHLGWVYIRVKFESEEVFYQKFGEVDVSRFGESELPPDFEVTFSKVTTLVNKSLVRKSELLEKMNNELKQELTNKLDSLEKVNVQLKKELSQAQQSNFTELRDGLILNFSKVGGRIHRMVVRSIQNQLKLVSEINNDGDRWATMGATVILKEGAQYLGFVVVKNDGKIGVKFDLTRLNSLDNQTLLASVV
What is the function of this protein?
May function by interacting with a small, flexible domain located at the C-terminus of the CP, forming a bridge between the virus particle and the internal surface of the vector nematode feeding apparatus.
What are the official names of this protein?
Protein 2b, 29.1 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the tobravirus protein 2b family.
What are the subcellular locations of this protein?
Virion.
Protein: GCS2_LEPCP
Sequence: MSLGEFAQSRSLTLGVELELQIVNTHDYDLAPSAVDLLRLMERHKVPGSVVPEMTDSMIELSTGICTDYDDALSQLREIRDALVSCAAQLNVGLCGGGTHPFQDWSQRRIFNKPRFQELSQLYGYLSKQFTIFGQHVHVGCPGPDQALVLLHGLSRFIPHLIALSASSPFVQGTDTGFDSARLNSVFAFPMSGRAPFVQTWDDFNVYFNKMTRTGVIKSMKDFYWDIRPKPEYGTIEVRVLDTPLTVEKAAAMAGYIQCLARWLRVEKPFELNEDDYLPYTYNRFQACRFGLDGIFVDPQTGEHRTLRDDILASFDKLELHAMELRAEGAINYLRADLLRIGNDASWIRHINDEEHLLAEVVRQQCQRWAGQGR
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: TRPD_HALH5
Sequence: MFKETLRECMEGHTLAERKAEQVMDAIMKGEATASQIASLLTVLRFRGETVAEMTGFARAMRRHSIQIEHSFSQVVDTCGTGGDDVGTFNISTATALLVSALGVPVAKHGNRAVSSKSGSADVLEALQIPIQSSPEEATASLQKHNMCFMFAPLYHVAMKHAVAPRKEIGFRTIFNLLGPLTNPARAEHQLIGVYDRNFAEKMAETLRRLGTKHSLLVAGHGGLDELSITGPSTVFEVKGDAIDRYELIPEDVGLERGDLAQIQVSTVQESATLIDQVLIGKANKSAQQIVLLNAGAALYAADRVDSIKAGVALAKEGIASGHVADHVRNLRQTDQEAEQHA
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: MZM1_PARBA
Sequence: MATTPLPNALSAYRLLLRATRIAFQGDFTTLHAARAEARKHFDQNRRLGVDTPKHIQHAVETAEILRTNVVQGVRVEGSGEAGKGEERYELRIHEHIERGDNDTIKTAGNKRIKAAVGKTCSQS
What is the function of this protein?
Assembly factor required for Rieske Fe-S protein RIP1 incorporation into the cytochrome b-c1 (CIII) complex.  Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane.  Modulates the mitochondrial matrix zinc pool (By similarity).
What are the official names of this protein?
Mitochondrial zinc maintenance protein 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family. MZM1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: XTHB_PHAAN
Sequence: MASSLLILCLVLVSLASSALCAAPRRPVDVPFGRNYIPTWAFDHIKYFNGGSEIQLHLDKYTGTGFQTKGSYLFGHFSMNIKMVPGDSAGTVTAFCLSSQNAEHDEIDFEFLGNRTGQPYILQTNVFTGGKGDREQRIYLWFDPTKAYHRYSVLWNMYQIVFLVDNIPIRVFKNLKELGVKFPFNQPMKVYNSLWNADDWATRGGLEKTDWSKAPFVAEYKGFHVDGCEASVNSRFCATQGKRWWDQTEFRDLDSFQWRRLKWVRQKFTIYNYCTDRTRYPQLPPECRRNRDI
What is the function of this protein?
Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET).  Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues (By similarity).
What are the official names of this protein?
Probable xyloglucan endotransglucosylase/hydrolase protein B, VaXTH2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 16 family. XTH group 1 subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Secreted, extracellular space, apoplast.
Protein: SELA_SHIB3
Sequence: MTTETRSLYSQLPAIDRLLRDSSFLSLRDTYGHTRVVELLRQMLDEAREVIRDSQTLPAWCENWAQEVDARLTKEAQSALRPVINLTGTVLHTNLGRALQAEAAVEAVAQAMRSPVTLEYDLDDAGRGHRDRALAQLLCRITGAEDACIVNNNAAAVLLMLAATASGKEVVVSRGELVEIGGAFRIPDVMRQAGCTLHEVGTTNRTHANDYRQAVNENTALLMKVHTSNYSIQGFTKAIDEAELVALGKELDVPVVTDLGSGSLVDLSQYGLPKEPMPQELIAAGVSLVSFSGDKLLGGPQAGIIVGKKEMIARLQSHPLKRALRADKMTLAALEATLRLYLHPEALSEKLPTLRLLTRSAEVIQIQAQRLQAPLAAHYGAEFAVQVMPCLSQIGSGSLPVDRLPSAALTFTPHDGRGSHLESLAARWRELPVPVIGRIYDGRLWLDLRCLEDEQRFLEMLLK
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TATA_ARATH
Sequence: MATSVATLSSPPPVSLPLLSSSRSSFFSNCFTVTTRPNTRSLVAIGRRIRQEPTRKPLTCNALFGLGVPELAVIAGVAALLFGPKKLPEIGKSIGKTVKSFQQAAKEFESELKTEPEESVAESSQVATSNKEEEKKTEVSSSSKENV
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across the thylakoid membrane.  Involved in delta pH-dependent protein transport required for chloroplast development, especially thylakoid membrane formation.  TATC and TATB mediate precursor recognition, whereas TATA facilitates translocation (By similarity).
What are the official names of this protein?
Sec-independent protein translocase protein TATA, chloroplastic, Protein THYLAKOID ASSEMBLY 4, Protein TWIN-ARGININE TRANSLOCATION A.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein. Note=The C- terminus is located in the stroma.
Protein: GUN1_HUMIN
Sequence: QKPGETKEVHPQLTTFRCTKRGGCKPATNFIVLDSLSHPIHRAEGLGPGGCGDWGNPPPKDVCPDVESCAKNCIMEGIPDYSQYGVTTNGTSLRLQHILPDGRVPSPRVYLLDKTKRRYEMLHLTGFEFTFDVDATKLPCGMNSALYLSEMHPTGAKSKYNPGGAYYGTGYCDAQCFVTPFINGLGNIEGKGSCCNEMDIWEANSRASHVAPHTCNKKGLYLCEGEECAFEGVCDKNGCGWNNYRVNVTDYYGRGEEFKVNTLKPFTVVTQFLANRRGKLEKIHRFYVQDGKVIESFYTNKEGVPYTNMIDDEFCEATGSRKYMELGATQGMGEALTRGMVLAMSIWWDQGGNMEWLDHGEAGPCAKGEGAPSNIVQVEPFPEVTYTNLRWGEIGSTYQELQ
What is the function of this protein?
The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose.
What are the official names of this protein?
Endoglucanase 1, Cellulase 1, Endo-1,4-beta-glucanase 1, Endoglucanase I.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 7 (cellulase C) family.
What are the subcellular locations of this protein?
Secreted.
Protein: ENTP5_CHICK
Sequence: MTSSRLPVLLALVFSSLSPVLSHSNREMWFQDLFPPNTCPINAKTKTFYGIMFDAGSTGTRIHIYTFVQKSPEILPELEGEIFESVKPGLSAYADQPEKGAESVKRLLDMAIDAVPPHLWKKTPVVLKATAGLRLLSEEKAQALLSEVKEVFEESPFLVPEDSVSIMDGSYEGILAWITVNFLTGQLSGQNQHTVGTLDLGGASTQITFLPRFEETLKESPTDFLTSFEMFNSTYKLYTHSYLGFGLKAARLATLGALNTEVADRQMFRSSCLPKQLEAEWHFGGVKYRYGGNKEGETGFKPCYLEVLKVVKGKLHQPDEIRGSSFYAFSYYYDRAADTNLIDYEQGGVLEVRDFERKAKEVCDNMERFSSASPFLCMDLTYITALLKEGFGFRDNTLLQLTKKVNNIETSWTLGATFHLLQSLGITY
What is the function of this protein?
Hydrolyzes nucleoside diphosphates with a preference for GDP, IDP and UDP compared to ADP and CDP (By similarity).  In the lumen of the endoplasmic reticulum, hydrolyzes UDP that acts as an end-product feedback inhibitor of the UDP-Glc:glycoprotein glucosyltransferases.  UMP can be transported back by an UDP-sugar antiporter to the cytosol where it is consumed to regenerate UDP-glucose.  Therefore, it positively regulates protein reglucosylation by clearing UDP from the ER lumen and by promoting the regeneration of UDP-glucose.  Protein reglucosylation is essential to proper glycoprotein folding and quality control in the ER (By similarity).
What are the official names of this protein?
Ectonucleoside triphosphate diphosphohydrolase 5, NTPDase 5, Guanosine-diphosphatase ENTPD5, GDPase ENTPD5, Uridine-diphosphatase ENTPD5, UDPase ENTPD5.
What is the protein family that this protein belongs to?
Belongs to the GDA1/CD39 NTPase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Secreted.
Protein: DUSB_HAEIN
Sequence: MRIGSYQLRNRVLLAPMAGITDQPFRRLCAYYGAGLTFSEMMSTNPQVWHTEKSKLRLAHSEDLGLNAVQIAGSDPLEMAQAAAINVEYGAQIIDINMGCPAKKVNRKLAGSALLQFPDLVEKILREVVSAVNVPVTLKIRTGWDKSNRNCVQIGKIAEQCGIQALTVHGRTRACLFEGEAEYDNIKAVKQAIAIPVIANGDIDSARKAKFVLNYTGADAIMIGRAALGNPWLFQAVENLIEHNSISQMPSLKEKCGQILRHIQELHQFYGEQKGYRIARKHVAWYLQGIQPDSVFKQTFNAISDPKEQLIVLEDFFNLILDKKNVRTTT
What is the function of this protein?
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.
What are the official names of this protein?
tRNA-dihydrouridine synthase B.
What is the protein family that this protein belongs to?
Belongs to the Dus family. DusB subfamily.
Protein: AMZA_SULIM
Sequence: MTEMKILIVTLTYIEKSIIDEIVNNLSSYGLEVDILFDSRKYLPISAFNWERLQYDAEKVLSFLKSKYDFNYDSIIFLADSDGYIDGYNFVFGLTIDNFAIIFLNRLREEFYNRKPDLELFMKRVVKEVTHEAGHTLGLGHCNTIGCVMNFSNTVEDVDKKQARFCKNCIYKIENLSKYLQRK
What is the function of this protein?
Probable zinc metalloprotease whose natural substrate is unknown.
What are the official names of this protein?
Archaemetzincin.
What is the protein family that this protein belongs to?
Belongs to the peptidase M54 family.
Protein: HRCA_LACLM
Sequence: MITERQRQILNLIVSLYAKDHTPIGSKSLLDSIQASSATIRNDMKALERLGLIQKEHTSSGRIPSVSGYKYFVENVIQLEEFSQNDLFKVMKAFDGDFYRLSDLFKTAAKSLSELTGLTSFVLNAPQRDQQLVSFEMVMLDNHSVLSVITLGTGEVRTNQFILPKSMTEADLAVFSNLVKERLVGKKVIDIHYTLRTEIPQIVQRYFKVTSEVLQLFESIFDDLFKEHLTVAGHKNIFDYATDNLAELYKLFSDDERMLHEIREITNNDEMRAVKFDNDEKFMKNLTIISQKFVIPYRGFGTLTVVGPVEMDYQRTLSVLDLVAKVLTMKLSDYYRYLDGNHYEISK
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: AT5G2_RAT
Sequence: MYACSKFVSTRSLIRSTSQLLSRPLSAVELKRPQMPTDEGLSCLAVRRPLTSLIPSRSFQTSAISRDIDTAAKFIGAGAATVGVAGSGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMVAFLILFAM
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
What are the official names of this protein?
ATP synthase F(0) complex subunit C2, mitochondrial, ATP synthase lipid-binding protein, ATP synthase membrane subunit c locus 2, ATP synthase proteolipid P2, ATPase protein 9, ATPase subunit c.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: CZCA_CUPMC
Sequence: MFERIISFAIQQRWLVLLAVFGMAGLGIFSYNRLPIDAVPDITNVQVQVNTSAPGYSPLETEQRATYPIEVVMAGLPGLEQTRSLSRYGLSQVTVIFKDGTDVYFARQLVNQRIQEAKDNLPEGVVPAMGPISTGLGEIYLWTVEAEEGARKADGTAYTPTDLREIQDWVVRPQLRNVPGVTEINTIGGFNKQYLVAPSLERLASYGLTLTDVVNALNKNNDNVGAGYIERRGEQYLVRAPGQVASEDDIRNIIVGTAQGQPIRIRDIGDVEIGKELRTGAATENGKEVVLGTVFMLIGENSRAVSKAVDEKVASINRTMPEGVKIVTVYDRTRLVDKAIATVKKNLLEGAVLVIVILFLFLGNIRAALITATIIPLAMLFTFTGMVNYKISANLMSLGALDFGIIIDGAVVIVENCVRRLAHAQEHHGRPLTRSERFHEVFAAAKEARRPLIFGQLIIMIVYLPIFALTGVEGKMFHPMAFTVVLALLGAMILSVTFVPAAVALFIGERVAEKENRLMLWAKRRYEPLLEKSLANTAVVLTFAAVSIVLCVAIAARLGSEFIPNLNEGDIAIQALRIPGTSLSQSVEMQKTIETTLKAKFPEIERVFARTGTAEIASDLMPPNISDGYIMLKPEKDWPEPKKTHAELLSAIQEEAGKIPGNNYEFSQPIQLRFNELISGVRSDVAVKIFGDDNNVLSETAKKVSAVLQGIPGAQEVKVEQTTGLPMLTVKIDREKAARYGLNMSDVQDAVATGVGGRDSGTFFQGDRRFDIVVRLPEAVRGEVEALRRLPIPLPKGVDARTTFIPLSEVATLEMAPGPNQISRENGKRRIVISANVRGRDIGSFVPEAEAAIQSQVKIPAGYWMTWGGTFEQLQSATTRLQVVVPVALLLVFVLLFAMFNNIKDGLLVFTGIPFALTGGILALWIRGIPMSITAAVGFIALCGVAVLNGLVMLSFIRSLREEGHSLDSAVRVGALTRLRPVLMTALVASLGFVPMAIATGTGAEVQRPLATVVIGGILSSTALTLLVLPVLYRLAHRKDEDAEDTREPVTQTHQPDQGRQPA
What is the function of this protein?
Has a low cation transport activity for cobalt, it is essential for the expression of cobalt, zinc, and cadmium resistance.  CzcA and CzcB together would act in zinc efflux nearly as effectively as the complete CZC efflux system (CzcABC).
What are the official names of this protein?
Cobalt-zinc-cadmium resistance protein CzcA, Cation efflux system protein CzcA.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KDM5C_MOUSE
Sequence: MELGSDDFLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEVDNFRFTPRIQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERRILDLYSLSKIVVEEGGYETICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEMYQSGANLVQCNTRPFDNEEKDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKLQIYGAGPKMMGLGLMAKDKTLRKKDKEGPECPPTVVVKEELGGDVKMESTSPKTFLEGKEELSHSPEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDGCDDNYHIFCLLPPLPEIPKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVHMVPTELVEKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSDSKRHLTPEEEEYATSGWNLNVMPVLEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAACPEKLDLNLAAAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKCKTTCFLSALACYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVRVALEVEDGRKRSLEELRALESEARERRFPNSELLQRLKNCLSEAEACVSRALGLVSGQEAGPDRVAGLQMTLAELRDFLGQMNNLPCAMHQIGDVKGILEQVEAYQTEAREALVSQPSSPGLLQSLLERGQQLGVEVPEAQQLQRQVEQARWLDEVKRTLAPSARRGTLAIMRGLLVAGASVAPSPAVDKAQAELQELLTIAERWEEKAHLCLEARQKHPPATLEAIIHEAENIPVHLPNIQSLKEALAKARAWIADVDEIQNGDHYPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAHSWREKASKTFLKKNSCYTLLEVLCPCADAGSDSTKRSRWMEKELGLYKSDTELLGLSAQDLRDPGSVIVAFKEGEQKEKEGILQLRRTNSAKPSPLALLTTASSTASICVCGQVPAGVGALQCDLCQDWFHGRCVTVPRLLSSQRSSLPSSPLLAWWEWDTKFLCPLCMRSRRPRLETILALLVALQRLPVRLPEGEALQCLTERAISWQGRARQVLASEEVTALLGRLAELRQRLQAESKPEESLAYPSDGGEGTGNMPKVQGLLENGDSVTSPEKVATEEGSGKRDLELLSSILPQLSGPVLELPEATRAPLEELMMEGDLLEVTLDENHSIWQLLQAGQPPDLKRVQTLLELEKAERHGSRTRGRALERRRRRKVDRGGEPDDPAREELEPKRVRSSGPEAEEVQEEEELEEETGGEVPPVPFPNSGSPSIQEDQDGLEPVLEAGSDTSAPFSTLTSRLLMSCPQQPSLQQL
What is the function of this protein?
Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code.  Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'.  Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'.  Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements (By similarity).  Represses the CLOCK-BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2.
What are the official names of this protein?
Lysine-specific demethylase 5C, Histone demethylase JARID1C, Jumonji/ARID domain-containing protein 1C, Protein SmcX, Protein Xe169, [histone H3]-trimethyl-L-lysine(4) demethylase 5C.
What is the protein family that this protein belongs to?
Belongs to the JARID1 histone demethylase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KDPB_YERPA
Sequence: MTHKQRAIFEPALVRTALLDAVKKLDPRVQWRNPVMFVVYLGSWLTTLIWLDILSGHTTGSAMFTGSIALWLWFTVLFANMAEALAEGRSKAQAASLRGVKKTSWAKKLSEARVDAPQEKVSADSLRKGDLVLIEAGDTVPCDGEVLEGGASVDESAITGESAPVIRESGGDFSSVTGGTRVLSDWLVVECRVNPGETFLDRMIAMVEGAKRRKTPNEVALTILLVALTIVFLLATATLYPFSVFSVEASQAGSPVTITVLVALLVCLIPTTIGGLLSAIGVAGMSRMLGANVIATSGRAVEAAGDVDVLLLDKTGTITLGNRQASEFLPAPGVTEQQLADAAQLSSLADETPEGRSIVVLAKQRFNLRERDLHSLNATFIPFSAQTRMSGVNVQERMIRKGAVDAIRRHVESNQGHFPPAVDDLVASVARTGGTPLVVAEGSRVLGVVALKDIVKGGIKERFAELRKMGIKTVMITGDNRLTAAAIAAEAGVDDFLAEATPEAKLALIRQYQAEGRLVAMTGDGTNDAPALAQADVAVAMNSGTQAAKEAGNMVDLDSNPTKLIEVVHIGKQMLMTRGSLTTFSIANDVAKYFAIIPAAFAATYPQLNALNIMQLHSPSSAILSAVIFNALVIVFLIPLALKGVSYKAMSAAALLRRNLWIYGLGGLLVPFVGIKLIDLLLTALNMG
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
What are the official names of this protein?
Potassium-transporting ATPase ATP-binding subunit, ATP phosphohydrolase [potassium-transporting] B chain, Potassium-binding and translocating subunit B, Potassium-translocating ATPase B chain.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PROC_MOUSE
Sequence: MWQFRVFLLLMSTWGISSIPAHPDPVFSSSEHAHQVLRVRRANSFLEEMRPGSLERECMEEICDFEEAQEIFQNVEDTLAFWIKYFDGDQCSAPPLDHQCDSPCCGHGTCIDGIGSFSCSCDKGWEGKFCQQELRFQDCRVNNGGCLHYCLEESNGRRCACAPGYELADDHMRCKSTVNFPCGKLGRWIEKKRKILKRDTDLEDELEPDPRIVNGTLTKQGDSPWQAILLDSKKKLACGGVLIHTSWVLTAAHCVEGTKKLTVRLGEYDLRRRDHWELDLDIKEILVHPNYTRSSSDNDIALLRLAQPATLSKTIVPICLPNNGLAQELTQAGQETVVTGWGYQSDRIKDGRRNRTFILTFIRIPLVARNECVEVMKNVVSENMLCAGIIGDTRDACDGDSGGPMVVFFRGTWFLVGLVSWGEGCGHTNNYGIYTKVGSYLKWIHSYIGEKGVSLKSQKL
What is the function of this protein?
Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids.  Exerts a protective effect on the endothelial cell barrier function.
What are the official names of this protein?
Vitamin K-dependent protein C, Anticoagulant protein C, Autoprothrombin IIA, Blood coagulation factor XIV.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted. Golgi apparatus. Endoplasmic reticulum.
Protein: MNMA_ACTP2
Sequence: MTNQTQLSSKTYDTHFAKLTAEQLAENAKKKVIIGMSGGVDSSVSAFILQQQGYQVEGLFMKNWEEDDDTDYCTAAADLADAQAVADKLGMKLHKINFAAEYWDNVFEHFLNEYKAGRTPNPDILCNKEIKFKAFLEYAAEDLGADYIATGHYVRRSGDDNNAQLLRGLDANKDQSYFLYTLSHKQVGQSLFPVGDIEKPIVRQIAEDLGLATAKKKDSTGICFIGERKFKDFLARYLPAQPGEIRTVGGKVVGRHDGLMYHTLGQRKGLGIGGVKGLSEDPFYVVEKDLINNVLVVAQGHDNSALLSSGLIATQLHWVDRQPIRENLRCTVKTRYRQTDIACEIQPIDDDTIRVIFDDPQIAVTPGQSAVFYQGEVCLGGGVIEEQLK
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXT_CARHZ
Sequence: MKIGVIAMQGAFREHEQTLARLGVETLRIRRPEQLSQIDGIIIPGGESTTIGKLLGDFNLMEPLRERILSGLPVFGTCAGMILLAKEIENSNQPRIGTMDIKVARNAFGRQVDSFEVDLEIPEVGQEPVRAVFIRAPYILEVKPSVQVLAKVDDKIVMARQDNMLVSAFHPELTDDLRIHRYFIEKVCKGL
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: GCSPA_STACT
Sequence: MSHRYIPLTEKDKQEMLETIGANSIEELFGDVPKEILLDRELDIPNGEDETTLLKRLSRIAKKNITKEDYTSFLGAGVYDHYTPAVVDAMISRSEFYTAYTPYQPEISQGELQAIFEFQTLICELTGMDVANSSMYDGITAFAEACILAFSQTKKNKIVVSKGLHYQALQVLHTYSKIRNDYEIVEVDLDGTVTDLEKLEDAIDDETAAVAVQYPNFYGSIEDLEKIKSLIKNKKTLFIVYTNPLSLGLLTPPGDFGADIVVGDTQPFGIPAQFGGPHCGFFATTKKLMRKVPGRLVGQTEDDHGNRGFVLTLQAREQHIRRDKATSNICSNQALNALASSIAMSALGKQGLQDIAVQNFENANYAKNQFKDAGIEVLPGTSFNEFVIKLDKPVKEVNDKLLEEGIIGGFDLSEVNEEFGQAMLIAVTELRTKDEIDTFVKKVGEING
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.