PharMolix/UniProtQA huggingface dataset:
Protein: SPAG7_DANRE
Sequence: MADLLGSILSSMEKPPTVHDQESRRKAREQAARLKKLEEDERRKKAEFRKKMEKEVSEFIKDSTLQKKKYNPMGKIERSILHDVAEVAGLTSFSFGEDEESRYVMLFKKEFAPSDEELEAYRKGEEWDPQKAEERRRLKEKAALEEEAASHTQKRPASPNSNYRDKYSHLIGTSAAKDAAHTLQANRAYGCVPVANKRDTRSIEEAMNEIRAKKRQKKGDEEAAGSGSSV
What are the official names of this protein?
Sperm-associated antigen 7 homolog.
Protein: CYAA_DICDI
Sequence: MASSSPMFNDHAIARSKYALNSVLQQTNELHDGNGGGGYTPSSPHLGGVSLNKSQNQPYTQYNNGGGGGGGGGGHINPMHLNLNSITNNHNNHHNHHPNTLSTPHNNNHNNNNHSTSHHPHSNSVANGGHLSQSITQQRGGLADLANAVINRKNRSDSVQTKMKPTDSASNIESWAKVEKFSSSIFDSEKSKKSNIFQKYTLRLKNSYEKGYLHQHYNSQIMLLRITNLIGIVAVSYGFTKEAIFMLIAIRILCFNLFAFSIFLSFLRNRELYKKLFHPLFLFSFTTFFITILLEYKTTTTTLILFLYVVIFCCLYALGCLLFIWMVMCNLMNAICFIIFIFLESTLDRNNLISFVIYILTMFLVGASHLYVLEKFRKESFIAEKKLIKESNILKNEKEKSSKLLNNILPDFIIENIVYDFEKRDIVIPEPEEYKSCSILCFDIVQFTNMSAKLDSPSRLVDLLTQVFREFDTVVLRNGCQKIKTDGDAYICACGLKSKKKAKKQMPNSKSTPLLQSTSSTSVNNIDLDKDNKDNNNNNNNNKNSNNNFKNKNNIINNNNNSNSNNNNNNNSNNNNINNSGNDDDDEEIEDSELEHFEKLIDVAIEIMNLDVLKETGNTEGIQVQFRCGIAAGSVYGGVIGSQKYQFDIWGDTIARSHTLEQLGQPGKVHVGETIMTHKNWLKKWQYNYNIVSNSECKDQEHDYEFHKAHGECITSYFVDWKDDYREKKKKDLSCDFSINKVLNAETIESKSNNNNYNNNNYNNNNYNNNYNNNNLNNNSNNNNNEYGSSSSSSSVLGEAVTEQIDCNNTNPPLQHKKSQSILTNNENDIVSPSLTSNSPILDTTVNNNNNNNNTNNNNKNQNNIYGNNNNNEEDFKIKSKSNSSFEIEMSNIKKPKSRFIDRVMGILHHVKISNDKIDKEIIQIDEDFVKVTKLRKYFLFFENLTTEKFFHKYVIINNVVETKFFLVIGLILHLMFYLDDHIMDSAPYFNSNVIYLVMGIAFLVYIGLSFTRIFRTPLVYQIAFFILLCAFGVCTVLELIRFQNPLARSSLTRVCATLFYLNVFHSLNFLSVLFLNLFIFSFFIICSILISPTLTNHLYETDYIGFVIVLLIQICSSYGMKLAMRKAWVVNCKINFKTISVNKEKDKFNFLLKSIFPQSALTKLRDMIDTPNIETKGIVYVQPHQDVSIMFIQIAGFQEYDEPKDLIKKLNDIFSFFDGLLNQKYGGTVEKIKTIGNTYMAVSGLDGSPSFLEKMSDFALDVKAYTNSVAISRVVRIGISHGPLVAGCIGISRAKFDVWGDTANTASRMQSNAQDNEIMVTHSVYERLNKLFYFDDEKEILVKGKGKMVTHVLKGKKDLEQTNKWFTKPPEVWEVNATPAGIASPLSGTLLGEIGSFTTPRFHLSS
What is the function of this protein?
Coordinates cell aggregation by synthesizing the cAMP that influences differentiation and morphogenesis of cells within a developing multicellular structure.
What are the official names of this protein?
Adenylate cyclase, aggregation specific, ATP pyrophosphate-lyase, Adenylyl cyclase.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell projection, uropodium. Note=In non-polarized cells ACA is uniformly distributed at the membrane but upon polarization it becomes highly enriched at the uropodium.
Protein: HSLU_FRATT
Sequence: MTQIMTPKTIVHELERHIIGQNDAKKAVAIALRNRWRRMQLDNEMRQEVTPKNILMIGPTGVGKTEIARRLAKLADAPFIKVEATKFTEVGYVGKDVESIIRDLVETAVKMKREEAKEKVTEKAARLAEDRILDVLIPPARTSESKVGFANEPAEDAASKKEKENKTREIFRKKIQNGELDDKEIEIEVAVAPKTIGVMGPPGMEDMTSQLQDLFSSLSTDKKKNKKMRIKDAIKLAQDEEAAKLVNEEDIKARALEAVEQNGIVFLDEIDKVCRKSSNSGADVSREGVQRDLLPLVEGSTVSTKYGVIKTDHILFIASGAFHVAKPSDLIPELQGRLPIRVELKSLEIEDFVRILREPDCSILKQYIALMKTEGIDLSFEEDAIRKIAEIAYKVNEEVENIGARRLHTVMERLLEKISFDAPELVEKNINITTDYVNEKLGNLVKNKDLSQYIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_FINM2
Sequence: MKTYIPKKDDIQRKWYVVDATDVVLGRLSTEVASILRGKNKPMFTPNADVGDYVIVINAEKVKLTGKKLEQKELRHYTGYAGGLKSITYKDLMQKDPERAVTHAIVGMLPHNSLGRQMAKKLRVYRGADHDHIAQNPEVLEIK
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RL27_SORC5
Sequence: MAHKKGGGSSRNGRDSNAQRRGVKVYAGAPVRAGNILVRQVGSSIHAGHNVGTGRDFTLFALVDGVVTYEWKSNTKKQVSVYPAS
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: OPGG_SALTY
Sequence: MMKMRWLGAAIMLTLYASSSWAFSIDDVAKQAQSLAGKGYEAPKSNLPSVFRDMKYADYQQIQFNSDKAYWNNLKTPFKLEFYHQGMYFDTPVKINEVTATTVKRIKYSPDYFNFGNVQHDKDTVKDLGFAGFKVLYPINSKDKNDEIVSMLGASYFRVIGAGQVYGLSARGLAIDTALPSGEEFPRFREFWIERPKPTDKRLTVYALLDSPRATGAYRFVIIPGRDTVVDVQSKVYLRDKVGKLGVAPLTSMFLFGPNQPSPTTNYRPELHDSNGLSIHAGNGEWIWRPLNNPKHLAVSSYAMENPQGFGLLQRGREFSRFEDLDDRYDLRPSAWITPKGDWGKGKVELVEIPTNDETNDNIVAYWTPDQLPEPGKEMNFKYTLTFSRDEDKLHAPDNAWVLQTRRSTGDVKQSNLIRQPDGTIAFVVDFVGADMKKLPPDTPVAAQTSIGDNGEIVDSNVRYNPVTKGWRLMLRVKVKDAKKTTEMRAALVNADQTLSETWSYQLPANE
What is the function of this protein?
Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis protein G.
What is the protein family that this protein belongs to?
Belongs to the OpgD/OpgG family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RR15_DAUCA
Sequence: MIKNSFSAIFFKEENEDNKGSVEFQVVSFTNRIRKLTSHLELHKKDYLSQRGLRKILGKRQRLLAYLSKKNRVRYKELIGQLEIRETKKN
What are the official names of this protein?
30S ribosomal protein S15, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LSPA_ECO7I
Sequence: MSQSICSTGLRWLWLVVVVLIIDLGSKYLILQNFALGDTVPLFPSLNLHYARNYGAAFSFLADSGGWQRWFFAGIAIGISVILAVMMYRSKATQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYVGDWHFATFNLADTAICVGAALIVLEGFLPSKAKKQ
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MST7_MAGO7
Sequence: MADPFAPRTMKRRNVKGLALTPAAPKPPPTAENAPIHRDSDQHAQLEIGIEFNLDLRPEDLEVIKDLGSGNGGTVSKVRHIPTNTVMARKVIHVEAKREMRKRIVRELQIMHSCNSEYIVTFYGAFLNENNDVIMCMEYADVGSLDRVSRVFGPIRVDVLGKIAEATLGGLTYLYAKHHIMHRDIKPSNILVNSRGSIKLCDFGVSGELINSIADTFVGTSTYMAPERIQGEKYTVKSDVWSFGLSIMELAIGKFPFAASEQLSDAESAPAGILDLLQQIVHEPAPKLPKSDAFPQILEDMIQKCLYKNPDDRPTPEELFERDPFVQAAKRTPVDLREWAFGLMERDNRKSHLAPQLSPATADLLRSSDSPTATYHGDDRPLETPTSAYRVDPRRGPAEGSAGLADQVDRLYIRD
What is the function of this protein?
Mitogen-activated protein kinase kinase; part of the MST11-MST7-PMK1 MAP kinase (MAPK) cascade that is essential for appressorium formation, penetration and invasive growth (PubMed:15749760, PubMed:21283781, PubMed:23454094, PubMed:27059015).  The MST11-MST7-PMK1 MAP kinase cascade transduces signals from the cell surface sensors MDB2 and SHO1 that recognize various surface signals such as surface hydrophobicity, cutin monomers, and rice leaf waxes (PubMed:21283781).  MST7 acts as the upstream MAPKK that directly phosphorylates MAP kinase PMK1 (PubMed:15749760).
What are the official names of this protein?
Mitogen-activated protein kinase kinae MST7, MAPKK MST7, MEK MST7.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
Protein: GUAC_ACIAC
Sequence: MEIFDYDNVLLLPRKCRVESRSECDASVTLGQRSFRLPVVPANMKTVVDEKICRWLASNGYFYVMHRFDLDNVQFVRDMHAAGCFASISLGVKQPDYDTVDRLVAEGLCPEYITIDIAHGHADTVKAMIAYLKQHLPQAFVIAGNVATPEAIIDLENWGADATKVGVGPGKVCITKLKTGFGTGGWQLSALKWCARVATKPIIADGGIRSHGDIAKSIRFGATMVMIGSLFAGHEESPGKTVEVDGEQFKEYYGSASDFNKGEYKHVEGKRILEPIKGRLADTLVEMEQDVQSSISYSGGRRLMDIRKVNYVILGGDNAGEHLLM
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
Protein: GAP4_CANAL
Sequence: MSYKGNDIEKQQSASTATGFNDKQIASTSEDATDRSHNIHGDTSSLDSRYTYETVDQEKNYFKRVYNSFKPMNLEEQGIDTSQLTPVERTIIASAKHPLARRLKARHLQMIAIGGSIGTGLFVGSGYALANGGPGAVLIGYVIVGYALLTVVNALGELSVQFPVSGSFNAFFSRFLEPSFGGTFGILYAASWCISLPSELIAAAMTIQYWNTEVNPAVWVAVFWVVIVVINLFGVKGYGEMEYFLSIIKVLAVVGFIILGICITCGVGDQGYIGGKYWHNPGAFNHGLKGVTSVFISAAFSFGGIELVALAASETANPRISLPAAVKSTFWRIFIFYILTAIIIGCLVPYTNDDLLNGTGIAASPFVIAVSQGGIRVVPHIMNAVVVIAVISVGNSSVYGCSRTLASLAVQGLLPKSMGYIDRGGRPLIAILFTSAIGLLGFLVVVDNEGDVFTWFFSICSLSSFFTWGAINVVHLRWRFALAAQGRSTDEIIFRSPLGTFGSWTGILVLILIVIGEVWVSIWPIGSPADVQQFWKNCLSLPLMIVMWAGFKTYHRSWNMLWVKLEDIDLDTGRREIDVELLKQELAEERQIIKSKPFVYRIYKFFF
What is the function of this protein?
Amino-acid permease involved in S-adenosylmethionine (SAM) transport and required for SAM-induced morphogenesis (PubMed:28028545).  GAP4 is also able to transport arginine and thialysine, and thus probably also lysine (PubMed:21764911).
What are the official names of this protein?
S-adenosylmethionine permease GAP4, SAM permease, Amino-acid permease GAP4.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NUCL1_ORYSJ
Sequence: MGKASKKSVAVAVAPAAVPAKGKGGKKREAEDEIEKAVSAKKQKAAAAPPAKAVPAPKADAKKAKKQPPPKKAASSSSGSSSEEDSSESEEEVKVQVKKTTKPVKQESSSDESSDESSDDEDAKPADPVANNGLKKGKPASSDSESDSDDEMDEDEKPAAPVKKTSVTAQKKKDDSDSSESESDESDSDEDVPTKSKAPAVAAKNDDSTDGSESESDSEDEDAAPKGAAKKESSSDEEDDSSEESSDDEPKQPQQKKAQEESSEESSEEDSDEEDEKLAKTPKKKTPAATKSQNDEPKTPASNQSQGTESATLFMGNLSFNLNQDQVKEFFQEVGEVISVRLATHEDGSSRGFGHVQFASSEEAKKALELHGCDLDGRPVRLDLAHERGAYTPHSRNDTGSFQKQNRGSSQSIFVKGFDSSLEESKIRESLEGHFADCGEITRVSVPMDRETGASKGIAYIDFKDQASFSKALELSGSDLGGYNLYVDEAKPKGDSRDGGGRRGGRSGDRFGGRSGDRFGGRSGGRFGGRDGGRRGGRGGRDGGRRGGRGGFQSRQSAGTASTGKKTTFGDE
What is the function of this protein?
Involved in pre-rRNA processing and ribosome assembly.
What are the official names of this protein?
Nucleolin 1, Protein NUCLEOLIN LIKE 1.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: NUOB_TRIL1
Sequence: MGVNQPLGGNVTVTSLDKLVNWVRKSSIWPMTFGLACCAIEMMATGASHNDLDRFGIIFRASPRQADCIIIAGTVTKKMLPVIQTVYEQMPEPKWVIAMGACACSGGIFDTYSVVQGIDEALPVDVYIPGCPPRPEALLYGLMKLQDKIMQESNSFGSVFGLGERVSTV
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: VREN_LAMBD
Sequence: MTGKEAIIHYLGTHNSFCAPDVAALTGATVTSINQAAAKMARAGLLVIEGKVWRTVYYRFATREEREGKMSTNLVFKECRQSAAMKRVLAVYGVKR
What are the official names of this protein?
Protein ren.
Protein: XERS_STRS7
Sequence: MKRDLLLTKIEEYKNIMPWYVLDYYQSKLSVPYSFTTLYEYLKEYKRFFEWLIDSDLSKAARIADVDLTTLEHLSKKDMEAFILYLRERPSLNTYSTKKGVSQTTINRTLSALSSLYKYLTEEVENEHGEPYFYRNVMKKVATKKKRETLAARAENIKQKLFLGDETMAFLDYVDKEYEHKLSNRAKASFRKNKERDLAIIALLLASGIRLSEAVNLDLKDVNLNMMLVEVTRKGGKRDSVNVAAFAKPHLEAYLSVRKDRYQAEKQDVAFFLTAYRGLPNRIDASSIEKMVGKYSESFKIRVTPHKLRHTLATRLYDTTKSQVLVSHQLGHASTQVTDLYTHIVNDEQKNALDKL
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.
What are the official names of this protein?
Tyrosine recombinase XerS.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KREM1_HUMAN
Sequence: MAPPAARLALLSAAALTLAARPAPSPGLGPECFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLGEHNYCRNPDGDVSPWCYVAEHEDGVYWKYCEIPACQMPGNLGCYKDHGNPPPLTGTSKTSNKLTIQTCISFCRSQRFKFAGMESGYACFCGNNPDYWKYGEAASTECNSVCFGDHTQPCGGDGRIILFDTLVGACGGNYSAMSSVVYSPDFPDTYATGRVCYWTIRVPGASHIHFSFPLFDIRDSADMVELLDGYTHRVLARFHGRSRPPLSFNVSLDFVILYFFSDRINQAQGFAVLYQAVKEELPQERPAVNQTVAEVITEQANLSVSAARSSKVLYVITTSPSHPPQTVPGSNSWAPPMGAGSHRVEGWTVYGLATLLILTVTAIVAKILLHVTFKSHRVPASGDLRDCHQPGTSGEIWSIFYKPSTSISIFKKKLKGQSQQDDRNPLVSD
What is the function of this protein?
Receptor for Dickkopf proteins.  Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6.  In the absence of DKK1, potentiates Wnt-beta-catenin signaling by maintaining LRP5 or LRP6 at the cell membrane.  Can trigger apoptosis in a Wnt-independent manner and this apoptotic activity is inhibited upon binding of the ligand DKK1.  Plays a role in limb development; attenuates Wnt signaling in the developing limb to allow normal limb patterning and can also negatively regulate bone formation.  Modulates cell fate decisions in the developing cochlea with an inhibitory role in hair cell fate specification.
What are the official names of this protein?
Kremen protein 1, Dickkopf receptor, Kringle domain-containing transmembrane protein 1, Kringle-containing protein marking the eye and the nose.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: SECY2_STRPS
Sequence: MTKIYSSIAVKKGLFTLFLLFIYVLGSRIILPFVDLNTKDFLGGSTAYLAFSAALTGGNLRSLSIFSVGLSPWMSAMILWQMFSYSKKLGLSSTAIEIQDRRRMYLTLMIAVIQSLAVSLRLPVQSSYSAILVVLMNTILLIAGTFFLVWLSDLNASMGIGGSIVILLSSMVLNIPQDVLETFQTVHIPTGIIVLLALLTLVFSYLLALMYRARYLVPVNKIGLHNRFKRYSYLEIMLNPAGGMPYMYVMSFLSVPAYLFILLGFIFPNHSGLAALSKEFMIGKPLWVYVYISVLFLFSIIFAFVTMNGEEIADRMKKSGEYIYGIYPGADTSLFINRLVLRFSVIGGLFNVVMAGGPMLFVLFDEKLLRLAMIPGLFMMFGGMIFTIRDEVKALRLNETYKPLI
What is the function of this protein?
Part of the accessory SecA2/SecY2 system specifically required for export of possible cell wall proteins.  The central subunit of a protein translocation channel.
What are the official names of this protein?
Accessory Sec system protein translocase subunit SecY2.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family. SecY2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TDCC_SALAR
Sequence: MSTTDSIVSSQTKQSSWRKSDTTWTLGLFGTAIGAGVLFFPIRAGFGGLIPILLMLVLAYPIAFYCHRALARLCLSGSNPSGNITETVEEHFGKTGGVVITFLYFFAICPLLWIYGVTITNTFMTFWENQLQMPALNRGVVALFLLLLMAFVIWFGKDLMVKVMSYLVWPFIASLVLISLSLIPYWNSAVIDQVDLSNIALTGHDGILVTVWLGISIMVFSFNFSPIVSSFVVSKREEYEKEFGRDFTERKCSQIISRASMLMVAVVMFFAFSCLFTLSPQNMADAKAQNIPVLSYLANHFASLSGTKSTFATVLEYGASIIALVAIFKSFFGHYLGTLEGLNGLVLKFGYKGDKTKVSMGKLNTISMIFIMGSTWIVAYANPNILDLIEAMGAPIIASLLCLLPMYAIRKAPSLAKYRGRLDNVFVTLIGLLTILNIVYKLF
What is the function of this protein?
Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system).
What are the official names of this protein?
Threonine/serine transporter TdcC, H(+)/threonine-serine symporter.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: QUEF_GLOC7
Sequence: MSNSIEQQQTPEVPPLKYGEREIAKGELFTFPNPRIGRHYQIHITLPEFTCKCPFSGYPDFATIYLTYVPNEKVVELKAIKLYINNYRDLYISHEEAVNQILDDFVAACDPLEVQIKGDYNPRGNVHTVIEVNYQKAN
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPK2_AUSRA
Sequence: SPPFAPRL
What is the function of this protein?
Myoactive.
What are the official names of this protein?
Pyrokinin-2, PK-2, FXPRL-amide.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ESPP_ECOLX
Sequence: MNKIYSLKYSHITGGLIAVSELSGRVSSRATGKKKHKRILALCFLGLLQSSYSFASQMDISNFYIRDYMDFAQNKGIFQAGATNIEIVKKDGSTLKLPEVPFPDFSPVANKGSTTSIGGAYSITATHNTKNHHSVATQNWGNSTYKQTDWNTSHPDFAVSRLDKFVVETRGATEGADISLSKQQALERYGVNYKGEKKLIAFRAGSGVVSVKKNGRITPFNEVSYKPEMLNGSFVHIDDWSGWLILTNNQFDEFNNIASQGDSGSALFVYDNQKKKWVVAGTVWGIYNYANGKNHAAYSKWNQTTIDNLKNKYSYNVDMSGAQVATIENGKLTGTGSDTTDIKNKDLIFTGGGDILLKSSFDNGAGGLVFNDKKTYRVNGDDFTFKGAGVDTRNGSTVEWNIRYDNKDNLHKIGDGTLDVRKTQNTNLKTGEGLVILGAEKTFNNIYITSGDGTVRLNAENALSGGEYNGIFFAKNGGTLDLNGYNQSFNKIAATDSGAVITNTSTKKSILSLNNTADYIYHGNINGNLDVLQHHETKKENRRLILDGGVDTTNDISLRNTQLSMQGHATEHAIYRDGAFSCSLPAPMRFLCGSDYVAGMQNTEADAVKQNGNAYKTNNAVSDLSQPDWETGTFRFGTLHLENSDFSVGRNANVIGDIQASKSNITIGDTTAYIDLHAGKNITGDGFGFRQNIVRGNSQGETLFTGGITAEDSTIVIKDKAKALFSNYVYLLNTKATIENGADVTTQSGMFSTSDISISGNLSMTGNPDKDNKFEPSIYLNDASYLLTDDSARLVAKNKASVVGDIHSTKSASIMFGHDESDLSQLSDRTSKGLALGLLGGFDVSYRGSVNAPSASATMNNTWWQLTGDSALKTLKSTNSMVYFTDSANNKKFHTLTVDELATSNSAYAMRTNLSESDKLEVKKHLSGENNILLVDFLQKPTPEKQLNIELVSAPKDTNENVFKASKQTIGFSDVTPVITTRETDDKITWSLTGYNTVANKEATRNAAALFSVDYKAFLNEVNNLNKRMGDLRDINGEAGAWARIMSGTGSASGGFSDNYTHVQVGVDKKHELDGLDLFTGFTVTHTDSSASADVFSGKTKSVGAGLYASAMVDSGAYIDLIGKYVHHDNEYTATFAGLGTRDYSTHSWYAGAEAGYRYHVTEDAWIEPQAELVYGSVSGKQFAWKDQGMHLSMKDKDYNPLIGRTGVDVGKSFSGKDWKVTARAGLGYQFDLLANGETVLRDASGEKRIKGEKDSRMLMSVGLNAEIRDNVRFGLEFEKSAFGKYNVDNAVNANFRYSF
What is the function of this protein?
Serine protease with cytotoxic effect.  Disrupts actin cytoskeleton resulting cell detachment in vitro.
What are the official names of this protein?
Serine protease EspP.
What are the subcellular locations of this protein?
[Serine protease EspP]: Periplasm. SUBCELLULAR LOCATION: [Secreted autotransporter protein EspP]: Secreted. Cell surface. SUBCELLULAR LOCATION: [Autotransporter protein EspP translocator]: Cell outer membrane; Multi-pass membrane protein. Note=The cleaved C-terminal fragment (autotransporter domain) is localized in the outer membrane.
Protein: GPPA_SERP5
Sequence: MLSSSALYAAIDLGSNSFHMLVVREVAGSIQTLARIKRKVRLAAGLDQNNLLSHEAMQRGWQCLKLFSERLQDIPRAQIRVVATATLRLASNADEFLQTAEQILGCPIQVISGEEEARLIYHGVAHTTGGPDQRLVVDIGGGSTELVTGTGAQAAQLYSLSMGCVTWLERFFSDRNLGQENFERAEQAAREMVRPIAPQLRQHGWQVCVGASGTVQALQEIMVAQGMDERITLSKLRQLKQRAIQCGKLEELEIEGLTLERALVFPSGLSILLAIFQELGIESMMLAGGALREGLVYGMLHLPVEQDIRSRTIRNLQRRYLLDTEQAERVSQLAANFSQQVSNEWQLDARCRELLHSACLIHEIGLSVDFKQAPQHAAYLIRHLDLPGFTPAQKKLLATLLQNQSNTIDLPLLSQQNALPPRTAQRLCRILRLAIIFASRRRDDTLPAVRLRANNDDELTVILPPGWLEQHPLRAEALDQESHWQSYVHWPLILEEQR
What is the function of this protein?
Catalyzes the conversion of pppGpp to ppGpp.  Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.
What are the official names of this protein?
Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase, Guanosine pentaphosphate phosphohydrolase, pppGpp-5'-phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the GppA/Ppx family. GppA subfamily.
Protein: NSP3_ROT41
Sequence: MLKMESTQQMASSIINTSFEAAVVAATSTLELMGIQYDYNEVYTRVKSKFDYVMDDSGVKNNLLGKAATIDQALNGKFGSAVRNRNWMTDTRTTARLDEDVNKLRMMLSSKGIDQKMRVLNACFSVKRIPGKSSSIIKCTRLMRDKIERGEVEVDDSFVEEKMEVDTIDWKSRYEQLEKRFESLKQRVNEKYTSWVQKAKKVNENMYSLQNVISQQQSQIADLQHYCNKLEVDLQNKISSLVSSIEWYMKSMELPDEVKTDIEQQLNSIDVINPINAIDDFESLIRNVILDYDRTFLMFKGLMRQCNYEYTYE
What is the function of this protein?
Plays an important role in stimulating the translation of viral mRNAs.  These mRNAs are capped but not polyadenylated, instead terminating in a conserved sequence 'GACC' at the 3' that is recognized by NSP3, which competes with host PABPC1 for EIF4G1 binding.  The interaction between NSP3 and host EIF4G1 stabilizes the EIF4E-EIF4G1 interaction, thereby facilitating the initiation of capped mRNA translation.
What are the official names of this protein?
Non-structural protein 3, NSP3, NCVP4, Non-structural RNA-binding protein 34, NS34.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP3 family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: KTNS_ASPNC
Sequence: MLADMCVGVYKAAMNYEIRPHEFSFNTQESLFTGLGLGFLAATAVVASPSLLDLPITAAEVVRIAMRAGILLYQKSQDLEQLSLDSSLESWTTVVRGLDESIVRGELEKFNKSMETPPSSRIYISVVEPDGSVFISGPPSGLREFFNKSGKVQSAPRAPLPVYGGPCHAAHLYDRTHTEWVVSKVNPEIASRRLSGHPLVLSMGDGQPLAGENARDLFESATYVLLTSIIRWDSVLAAVKKLPHWKQDTKLQLETFRPSSPAVHGLISAVQSEYPDCTVSVDDLGDWIIDNSLEPPTIPIDSRIAVVGMSCRLPGGSDDLQRFWELLEDGRDVHQKVPGNRYDVESHTDMTGRRLNTSHTPFGCFIDSPGLFDASFFDMSPREAGQTDPTHRLALLTAYEALEYSGYVPNRTRSTTRDRVGTVYGQCSDDYREANAGQNIDMYFIPGNYRAFAPGRISYFFKFSGPSFNCDTACSASLAAVQIACSALIRGEADMVVAGGLNILTGSDSFAGLSRGFFLSKTGNCKVFDDGADGYCRADGIGSIVLKRLSDAQQDNDNILGVILGTATNHSSHAISITHPHAPTQEHLYRSVLSQAGIGPHDVDLVEMHGTGTQAGDAAEIESVTRVFSPPVPRRSHPLYISSVKANLGHGEAAAGITALMKALLIFQHNAIPRHVGIKTALNSKFPDLERLNVHIPKETIPWPYRSNRKRYVMINNFSAAGGNTSLLLEEPPVRPDPQGPPQTRFVVALSAKSTTSLRRNLESLITWLEGNRSARLASLAYTTTARRMHHKHRIAVHGASVAEIIQALHQRGSRAELGLLVSKPPSVAFIFSGQGSFYAGVGSQLFKEYPPYREQLQRLDEICQQNGFGSILPAITDTDADVSQLSALVTQLTTVCVQIALCRLWRTLGVKPAVVIGASLGEYAALYAAGALSASDAIFLVGQRTLLMQKLCTANSYGMLAVQGSVDDIRRCVQDRTYEVACINAPRSITICASIKDIVDIQQSLVSQGYRSVKLNVPFAFHSSQMDPILDRYEEIAKAVSFRSLQIPLISSTLADAAVQSRSLVASLFLRENTRAPARFAEAVAKAQDMGLVNSHTVWVEIGVHSTYSGAVRATVADLQAIVPSLRSDETNWHTLAVSMCTLQETGVPLDWNEWYRPFEPEVRLLDLPSYRWDLKNHWIQYNGDWLLVKDKRPRTDQISAATPSLRTALVHQIMEESFRPDGGEIVVQSDVMDKEFFAVASGHKMSGRPLVSVFSYPDIAFTLARYMYSRLKPESPLPAMDFGQVRVLQGLLPRKDRSKPQWVRMRMRADPQCAALQLSISGLSDESSRHVEEKLASGVVRCGDRQSWQDEWADYAHLLTTRIVTLQQMAENGQASRVSRDLVYTLFKNIVDYADHYRGIQSAVLHGLEAVADVILAPSNDSRWTAPPHHIDPITHVGGLVLNAGHATDHHNTIYVMEGWKSMRFAEELVAGELYRSYVKMNPARDGSGFFVGDVYVMREDHIVGKVRGMTLRPLPRILMNRFFDPPDDGDGLATQHIQPHDLPQVQHQPSPTTDSGPDDDPKDPNTGPLTPEVDLPVAPSVEKANTKLVRGALALLAAETGVEPDGLTDETEVSALGIDSLLSLVLVEKFATELQVNIQSSFFLESPTIRELKEYLTASW
What is the function of this protein?
Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of the bicoumarin kotanin (PubMed:22945023, PubMed:26389790).  The non-reducing polyketide synthase ktnS first catalyzes the formation of the pentaketidic 4,7-dihydroxy-5-methylcoumarin from acetyl coenzyme A and 4 malonyl coenzyme A molecules (PubMed:17315249, PubMed:22945023).  Further O-methylation by ktnB leads to the formation of 7-demethylsiderin (PubMed:17315249, PubMed:22945023, PubMed:26389790).  Then, an oxidative phenol coupling catalyzed by the cytochrome P450 monooxygenase ktnC forms the 8,8'-dimer P-orlandin via dimerization the monomeric precursor, 7-demethylsiderin (PubMed:26389790).  P-orlandin is subsequently O-methylated in a stepwise fashion to demethylkotanin and kotanin (PubMed:22945023).
What are the official names of this protein?
Kotanin synthase, Kotanin biosynthesis cluster protein S, Non-reducing polyketide synthase ktnS.