PharMolix/UniProtQA huggingface dataset:
Protein: RR7_MESVI
Sequence: MSRRSTPKKRIIDSDPIYRSRLVTMLISHILKEGKKSLAQKIFYQAMKNIEEKTEKDPLKVLQQAVLNATPLVEVKARRLGGSTYQVPREVKAERGTALALRWLLSSARQRPGRNMVAKLTNEIVDAANETGNAIRKREETHRMAEANKAFSHYRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ATPE_LATSS
Sequence: MMAEEQKVLTVNIVTPDGVVYDHHASMLVVPAMAGQLGIMANHEPIITPLEIGEIRVKRTDNPGHEDAIAITGGFMEVSHNIASIVADGAERARDINLSRAQRAKQRAEDAIKTASEKHDSDELRRAQIALQRAMNRIDVKNHLQ
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MLTF_ENT38
Sequence: MKKFKINYLLIGIVTLLLAAALWPSIPWFGKAENRIAAIQSRGELRVSTLDSPLTYNNVNGKIIGLDYELAQQFADYLGVKLKITVRQNISQLFDDLDNDDADLLAAGLVYNSERSKNYQPGPTYYSVSQQVVYRVGGVRPRTMATLNDQQLTVAPGHVVIDDLRALKEKKYPDLSWKVDEKLGTTALLEQVKDKKLAYTIADSVAISFFQRVHPEIAVALDVTDEQPVTWFSPLDDDQTLSAAILDFFNSMNEEGTLARLEEKYLGHGGDFDYVDTRSFLRAVDSVLPDLQPLFEKYAEEIDWRLLAAISYQESHWDAQATSPTGVRGLMMLTKNTAQSLGLTDRTDAEQSISGGARYLQDMMAKVPDTVPEEERIWFALAAYNMGYAHMLDARALTAKTKGNPDSWSDVKQRLPLLSQKPLYNKLTYGYARGHEAYAYVENIRKYQISLVGYLMEKEKEVTKAKQIAQSYPVVSPHELNHPATTSILPFVAFSADGAFERNHLIAPNTLVQAPRR
What is the function of this protein?
Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product.  Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus.  Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase F, Murein lyase F.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane.
Protein: PSAB_PINTH
Sequence: MASRFPKFSQGLAQDPTTRRIWFGIATAHHFESHDDITEERLYHKIFASHFGQLAIIFLWTSGNLFHVAWQGNFEAWVRDPLHVRPIAHAIWDPHFGQPAIEAFTRGGAPGPVNIAYSGVYQWWYTIGLRTNEDLYAGALFLLFLSVIFLIAGRLHLQPKWRPSVSWFKNAESRLNHHLSGLFGVSSLAWTGHLVHVAIPESRGVHVRWDNFLDVLPHPEGLEPLFTGQWNLYAQNPDSSSHLFGTSQGAGTAILTFLGGFHPQTQSLWLTDMAHHHLAIALVFSIAGHMYRTNFGIGHSMEDILEAHVPPGGLLGRGHKGLYNTINNSLHFQLGLALASLGVITSLVAQHMYSLPPYAFIAQDFTTQAALYTHHQYIAGFIMTGAFAHGAIFLIRDYNPEQNKDNVLARMLEQKEAIISHLSWVSLLLGFHTLGLYVHNDVMLAFGTPEKQILIEPIFAQWIQSAHGKTLYGFDILLSSTSGPSFDAGKSIWLPGWLNAINDNNNSLFSTIGPGDFLVHHAIALGLHTTTLILVKGALDARGSRLMPDKKDFGYSFPCDGPGRGGTCDISAWDAFYLAVFWMLNTIGWVTFYWHWKHITLWQGNVAQFNESSTYLMGWSRDYLWLNSSQLINGYNPFGMNSLSVWAWMFLFGHLVWATGFMFLISWRGYWQELIETLAWAHERTPLANLVRWRDKPVALSIVQARLVGLAHFSVGYIFTYAAFLIASTSGKFG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2, PSI-B, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: MUTL_METTP
Sequence: MPRIHILDEETVSRIAAGEVIERPASVVKELIENSIDAGASRIIIEVENGGISLIKLVDDGCGIEREDLPLAFQRHATSKISTADDLFRLKTLGFRGEALSAIASVSKCVEVHTRTRYSPVGTYLRLENGRVAEIKDDGCPYGTSIEVRGLFETIPARLKHLSSPSQELARIAEIVTQMAIIHHRISFELSSGRRTLFRSNASETWDDALIRAFGLRTAKGMISIIAEGDGFDLHGMISSHDSSHHGSELILVYVNSRPVYSKVVVQALREAYRGFLQSGRSPLAVISIEIEPSLVDVNVHPAKREVRFLREDEVYDAVRDAALSALRSSAIPSPPPPARIAEPQLWSAKPQIQRTLPLEVQAEQRISEPLIRIVGQALDLYIIVEDDDGIMLVDQHAAAERIRYEHLLEKCKSGSISQELIQPVTVELSPGEVALLDSFSGELGEIGFEIDPFGGRAYSVRSVPAAAGLESPESIRDVLREILNLGRVCRASFRDEALKHLACRGSIKSGERLSESAMLRLLTDLFACDNPRTCPHGRPVVVRISSESLEKMFGRR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: SKN1_YEAST
Sequence: MSVRNLTNNRHSNSENSVSGSENSFYSSNEQSRQSSSLEPADGQNVRVSGNPFLGSEEFDEDYNSPSGDDERRGANEYSSSSSINYNNDPNSDTSLLANEKNSPERNGQRMSDYKGYYAKTNLTSANNLNNHNNNNYKNIISSSNDNSFASHLQPPDRNLPSHPSSNNMSSFSNNSLIKSPPPFDRYPLVGTRHISAAQSQSQNLINEKKRANMTGSSSSAHDSSLSSTNLYMGEQDFSPFGGYPASFFPLTLDEKEDDDYIHNPNVEEEAKLDRRRFVDDFKHMDRRSFLGLLGILFLFMAGIFIFIVLPAITFSGVVYHHEHVHAANSAGSSSSNTTSKSLTEYQYPQLAAIRTTLVDPDTPDSAKTRVAKDGSKWQLVFSDEFNAEGRTFYDGDDQFWTAPDIHYDATKDLEWYSPDAVTTTNGTLTLRMDAFRNHDLYYRSGMVQSWNKLCFTEGALEVSANLPNYGRVTGLWPGMWTMGNLGRPGYLASTQGVWPYSYEACDAGITPNQSSPDGISYLPGQKLSVCTCDNEDHPNQGVGRGAPEIDILEGEADTILGVGVASQSLQIAPFDIWYMPDYDFIEVYNFTTTTMNTYAGGPFQQAVSAISTLNVTWYEFGEEAGYFQKYAIEYLNDDDNGYIRWFVGENPTFTLYATSLHPSGNIDWRRISKEPMSAILNLGISNNWAYIDWQYIFFPVTMSIDYVRLYQPKGSTSITCDPEDYPTYDYIQSHLNAYYNANLTDWEQAGYTFPKNILTGGCSSSKFSLS
What is the function of this protein?
Required for synthesis of the major beta-glucans of the yeast cell wall.
What are the official names of this protein?
Beta-glucan synthesis-associated protein SKN1.
What is the protein family that this protein belongs to?
Belongs to the SKN1/KRE6 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: YYAM_BACSU
Sequence: MKHLNIYIMLLGFSIFTGATFNLAKYTVGYFSPSSSAAWRFGLAAAVMLIILIFTEGIKKSQLRKNAVSYIVLGIIGIFGFNALFFVGLKYTSPVNGALIMGLNPLLTAILARIILKDNMTKKQVLGIFFAFIGVLLVITQGSIETIKTLSISGGDLIIFTGNVCWALYGVLGRRFVKDGTPLSTTTYTMVIGAVSLIVVSLFTSKPVSLSNIPIGVWGAIAFMAFFTSVLGYLWWNQGIKEIGASKTSLFFNLVPVVTMIISFAVGTPIKVFQVIGAVLVILGVLTASGVIRIPKYNTKEQSAI
What are the official names of this protein?
Uncharacterized transporter YyaM.
What is the protein family that this protein belongs to?
Belongs to the EamA transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KCNG3_HUMAN
Sequence: MTFGRSGAASVVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRHSEAFGFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRMSDTYTFYSADEPGVLGRDEARPGGAEAAPSRRWLERMRRTFEEPTSSLAAQILASVSVVFVIVSMVVLCASTLPDWRNAAADNRSLDDRSRYSAGPGREPSGIIEAICIGWFTAECIVRFIVSKNKCEFVKRPLNIIDLLAITPYYISVLMTVFTGENSQLQRAGVTLRVLRMMRIFWVIKLARHFIGLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKDFTSIPAACWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYHELKFRSARYSRSLSTEFLN
What is the function of this protein?
Potassium channel subunit that does not form functional channels by itself (PubMed:11852086).  Can form functional heterotetrameric channels with KCNB1; this promotes a reduction in the rate of activation and inactivation of the delayed rectifier voltage-gated potassium channel KCNB1 (PubMed:11852086, PubMed:19074135).
What are the official names of this protein?
Potassium voltage-gated channel subfamily G member 3, Voltage-gated potassium channel subunit Kv10.1, Voltage-gated potassium channel subunit Kv6.3.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. G (TC 1.A.1.2) subfamily. Kv6.3/KCNG3 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasm. Note=Has to be associated with KCNB1 or possibly another partner to get inserted in the plasma membrane (PubMed:12060745). Colocalizes with KCNB1 at the plasma membrane (PubMed:12060745, PubMed:19074135). Remains intracellular in the absence of KCNB1 (PubMed:12060745).
Protein: MMP14_HUMAN
Sequence: MSPAPRPPRCLLLPLLTLGTALASLGSAQSSSFSPEAWLQQYGYLPPGDLRTHTQRSPQSLSAAIAAMQKFYGLQVTGKADADTMKAMRRPRCGVPDKFGAEIKANVRRKRYAIQGLKWQHNEITFCIQNYTPKVGEYATYEAIRKAFRVWESATPLRFREVPYAYIREGHEKQADIMIFFAEGFHGDSTPFDGEGGFLAHAYFPGPNIGGDTHFDSAEPWTVRNEDLNGNDIFLVAVHELGHALGLEHSSDPSAIMAPFYQWMDTENFVLPDDDRRGIQQLYGGESGFPTKMPPQPRTTSRPSVPDKPKNPTYGPNICDGNFDTVAMLRGEMFVFKERWFWRVRNNQVMDGYPMPIGQFWRGLPASINTAYERKDGKFVFFKGDKHWVFDEASLEPGYPKHIKELGRGLPTDKIDAALFWMPNGKTYFFRGNKYYRFNEELRAVDSEYPKNIKVWEGIPESPRGSFMGSDEVFTYFYKGNKYWKFNNQKLKVEPGYPKSALRDWMGCPSGGRPDEGTEEETEVIIIEVDEEGGGAVSAAAVVLPVLLLLLVLAVGLAVFFFRRHGTPRRLLYCQRSLLDKV
What is the function of this protein?
Endopeptidase that degrades various components of the extracellular matrix such as collagen.  Activates progelatinase A.  Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development (By similarity).  May be involved in actin cytoskeleton reorganization by cleaving PTK7 (PubMed:20837484).  Acts as a positive regulator of cell growth and migration via activation of MMP15.  Involved in the formation of the fibrovascular tissues in association with pro-MMP2 (PubMed:12714657).  Cleaves ADGRB1 to release vasculostatin-40 which inhibits angiogenesis (PubMed:22330140).
What are the official names of this protein?
Matrix metalloproteinase-14, MMP-14, MMP-X1, Membrane-type matrix metalloproteinase 1, MT-MMP 1, MTMMP1, Membrane-type-1 matrix metalloproteinase, MT1-MMP, MT1MMP.
What is the protein family that this protein belongs to?
Belongs to the peptidase M10A family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Melanosome. Cytoplasm. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Forms a complex with BST2 and localizes to the cytoplasm.
Protein: KAD_SYNP6
Sequence: MARLIFLGPPGAGKGTQAVVVAEQLQLAHISTGELLRAAVTAQTPLGIEAKGYMDRGELVPDSLVLGLVRDRLQQPDTANGWILDGFPRNRSQAEALNLLLTEINQQVDRAVNLDVPDPVIIERMLARGRADDTESVIRRRLEVYREQTAPLIDFFRDRQQLLAIDGNSEVAAVTDRLVSALQVAA
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SKG1_YEAS1
Sequence: MTASTSVAVGCAVGIPVGVGIIIAVCFWFNLQKRYKREEQDDRELERAIYDESGFVSFDNFGPLRDSKDEAALASSELKNPDHTSGSSEGSAHPEEKDGKSRDQEKPLGKKNSKYYVPAYRRKINLLQVRNNNYGNNARQKSVVDLPSINNSSNVSLSSSQRHITKRQISVYDQMVPVISDEGPKFFADPSSDTNTSNDQNKASMIELKHNTRQSSNENLIRKLQNQDFGSYYPRRASSSFLNGNISNASFHTRNSSITSVNKRDALEDVFATPKSAAQSQLPNTFDKDNEGIDADHSVKDSRSAITDKDKNIYKLQNNYDVGNIGEIAEEDQYENEFTNYSQSKREFIESLRPK
What is the function of this protein?
Plays a role in cell wall integrity.  Affects the cell wall polymer composition in the growing region of the cell (By similarity).
What are the official names of this protein?
Suppressor of lethality of KEX2 GAS1 double null mutant protein 1.
What is the protein family that this protein belongs to?
Belongs to the SKG1 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type III membrane protein; Cytoplasmic side. Bud membrane; Single-pass type III membrane protein; Cytoplasmic side. Note=Localizes on the inner surface of the plasma membrane at the bud and in the daughter cell. Localizes at an incipient bud site in the cells with emerging buds, a bud tip in small- or medium-budded cells, and a cell periphery in large-budded cells.
Protein: MEF2C_BOVIN
Sequence: MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDIVETLRKKGLNGCDSPDPDADDSVGHSPESEDKYRKINEDIDLMISRQRLCAVPPPNFEMPVSIPVSSHNSLVYSNPVSSLGNPNLLPLAHPSLQRNSMSPGVTHRPPSAGNTGGLMGGDLTSGAGTSAGNGYGNPRNSPGLLVSPGNLNKNMQAKSPPPMNLGMNNRKPDLRVLIPPGSKNTMPSVSEDVDLLLNQRINNSQSAQSLATPVVSVATPTLPGQGMGGYPSAISTTYGTEYSLSSADLSSLSGFNTASALHLGSVTGWQQQHLHSMPPSALSQLGDRTTTPSRYPQHTRHEAGRSPVDSLSSCSSSYDGSDREDHRNEFHSPIGLTRPSPDERESPSVKRMRLSEGWAT
What is the function of this protein?
Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes.  Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development.  Enhances transcriptional activation mediated by SOX18.  Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission.  Crucial for normal neuronal development, distribution, and electrical activity in the neocortex.  Necessary for proper development of megakaryocytes and platelets and for bone marrow B-lymphopoiesis.  Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B-cells.  May also be involved in neurogenesis and in the development of cortical architecture (By similarity).
What are the official names of this protein?
Myocyte-specific enhancer factor 2C.
What is the protein family that this protein belongs to?
Belongs to the MEF2 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, sarcoplasm.
Protein: PLH13_FORAG
Sequence: MTSEMKKFSKIVLFGLLISPLLASSQTKKDANQKPNIILIMADDLGWTDLSSPNTSLGYGSKYYESPNIDRLAQQGKSFAYAYTQQNCQPTRAALLSGQYATGAQNGVYNVGSLKRASKGVVTPIMPHNQNNYLQEDCVSMFETLKTAGYHTAWFGKFHAIKLGKQAESYMGVDYNVALHKETSATVNGVKVKNEFFAQNDDAKGWMFEIDNLKPYAQPYDAAYLQKVLEPIKNGNNPWLLEGTPKHLTDALGDAVVGYIKDRSKADSPFFAYIPFHAVHVSILPRLDLEAKYKAKKSLDPRHTQADYAAFVELLDQTVGRVLNALEDPNGDGNKADGIAENTMVIFYSDNGGFMGPTNNSPLRLRKGTYYEGGVRVPLIFKYPGVITPNSVNTTQEVHTIDFYPTLAEIAGAKLPSPKVQEMDGKSIASVLREESQVRDDKNELFWHFPGYMDVRNMPQSVIHYRHSDNQHYKLFYRYEDESFELYNLSNDLGETTNLLAENPSQQTLDLALKMNNKLRAWLIKNNAPTGIWAKNCEKVPYPKKDAVKKYIK
What is the function of this protein?
Sulfatase that may be involved in ulvan degradation (Probable).  Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall.  It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl) (Probable).
What are the official names of this protein?
Sulfatase, Arylsulfatase, Polysaccharide utilization locus H protein P13, PUL H protein P13, Sulfatase family S1 subfamily 16 protein P13, P13_S1_16.
What is the protein family that this protein belongs to?
Belongs to the sulfatase family.
What are the subcellular locations of this protein?
Secreted.
Protein: GDL87_ARATH
Sequence: MPTNNTPFLTIFLLFLGLLRFDSFPGLEAATGKLASIPGLYVFGDSLVDAGNNNYLPISISKANYPHNGVDFPNKKPTGRFCNGKNAADAIAEKFGLPLPPPYLSLRGLLKREKRKSAAVTGVNFASGGAGIFNSSDQKLGQAIPLSKQVNNWLSIHEEVMKLEPSAAQLHLSKSLFTVVIGSNDLFDYFGSFKLRRQSNPQQYTQLMADKLKEQLKRIHDSGARRFLIIGVAQIGCTPGKRAKNSTLHECDEGANMWCSLYNEALVKMLQQLKQELQGSITYTYFDNYKSLHDIISNPARYGFADVTSACCGNGELNADLPCLPLAKLCSDRTKHLFWDRYGHPTEAAARTIVDLMLTDDTHYSSPITLTQLVST
What are the official names of this protein?
GDSL esterase/lipase At5g55050, Extracellular lipase At5g55050.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family.
What are the subcellular locations of this protein?
Secreted.
Protein: I2B9_CONIM
Sequence: MFRVTSVLLVIVLLNLVVLTNACHMDCSKMTCCSGICCFYCGRPMCPGTRRALLQRLVGHQR
What is the function of this protein?
Probable neurotoxin.
What are the official names of this protein?
Conotoxin Im11.9, Conopeptide im007.
What is the protein family that this protein belongs to?
Belongs to the conotoxin I2 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NUP62_HUMAN
Sequence: MSGFNFGGTGAPTGGFTFGTAKTATTTPATGFSFSTSGTGGFNFGAPFQPATSTPSTGLFSLATQTPATQTTGFTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSNLTNAISSTVTSSQGTAPTGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSGFNIGSAGNSAQPTAPATLPFTPATPAATTAGATQPAAPTPTATITSTGPSLFASIATAPTSSATTGLSLCTPVTTAGAPTAGTQGFSLKAPGAASGTSTTTSTAATATATTTSSSSTTGFALNLKPLAPAGIPSNTAAAVTAPPGPGAAAGAAASSAMTYAQLESLINKWSLELEDQERHFLQQATQVNAWDRTLIENGEKITSLHREVEKVKLDQKRLDQELDFILSQQKELEDLLSPLEELVKEQSGTIYLQHADEEREKTYKLAENIDAQLKRMAQDLKDIIEHLNTSGAPADTSDPLQQICKILNAHMDSLQWIDQNSALLQRKVEEVTKVCEGRRKEQERSFRITFD
What is the function of this protein?
Essential component of the nuclear pore complex (PubMed:1915414).  The N-terminal is probably involved in nucleocytoplasmic transport (PubMed:1915414).  The C-terminal is involved in protein-protein interaction probably via coiled-coil formation, promotes its association with centrosomes and may function in anchorage of p62 to the pore complex (PubMed:1915414, PubMed:24107630).  Plays a role in mitotic cell cycle progression by regulating centrosome segregation, centriole maturation and spindle orientation (PubMed:24107630).  It might be involved in protein recruitment to the centrosome after nuclear breakdown (PubMed:24107630).
What are the official names of this protein?
Nuclear pore glycoprotein p62, 62 kDa nucleoporin, Nucleoporin Nup62.
What is the protein family that this protein belongs to?
Belongs to the nucleoporin NSP1/NUP62 family.
Protein: RTP5_HUMAN
Sequence: MDRAGADMWASTFTLAMAERKPQDVWVLLPEHSLVPGCLDGGGVQYLLVGLSRLQCGHCPGTWDSAHVHVLFHLWWDRASHRGLVKMRIWGQRCRLCPAPGDCQVRPPGEQPFLSRLVLHILQDCYGDGPGPARHPREAYEGCCEACELGVCFLQKAPDPAWSANATKGNFPATAWGGTGTVSRGKPLSTPGDDLGKGGVVIAIPFSLVGTSNDQVPIAEGPAPPAGASLPVTGSCEALVIGQGSIFLSGDSVAMPGGKGFPVAIGDPLFHGPGLLGSSIQTFELKGFLFKGRGSLCSPVGVAQGWGPISLNNGLVPVGKHTPTVFYCVGLSASGEGSLTFPSSLTSIFTNTLSEPTDGPVATKEASITFPFIFTDVKDAVAEVAEGNGKEGGGQGLVPVGHDALPETNAGGLPSQVKGSLALPFPADVQGKDAFTDITEGKEKEGGLVTAGHDAPLEANAEGPITVSEGCITIPFAVFDVIKRKGGGHVAYGPQGNGCFSQGYYQKRQLRSRFHKARCGCRREEDERPGRACRRPHAEPYEDFWIWVSMTVCVFWLMCMCRLNPGIYPQQV
What are the official names of this protein?
Receptor-transporting protein 5, 3CxxC-type zinc finger protein 5, CXXC-type zinc finger protein 11.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: METK_BORAP
Sequence: MNKIIAANQTLTSEAVSEGHPDKIADQISDAILDEMLKVDKNAKVACEVIIAQNLVVIAGEINSPVKKNIDIKEIAKNIIKDIGYTNIDYGLDYKTITVIDAVGNQSRDIINAIEKEGSNTLGAGDQGIIFGYACDDTKNFLPAPYELANSILKKASNLRKSGAIEWLRPDSKSQVTMEYDKNRRPIKIKNIVVSHQHHPNISQKLMRQTIIEEIIKPTIQDKSILDENTTYCINPSGNFVIGGPTGDTGLTGRKIIADSYGGFARHGGGAYSGKDATKVDRSAAYMARYIAKNMVAAGISKEFELQLAYAIGIENPISIQITAGINDPKYASKILNFIVNNFDLTPNGIIEKLKLKQPIYLKTCTYGHFGKNEFEWEKLDFVKKIQTVLKK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATA2_PSINU
Sequence: AEVLMDFPQLTMTLPDGREESVMKRTTLVA
What is the function of this protein?
Catalytic subunit of the peripheral V1 complex of vacuolar ATPase.  V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
What are the official names of this protein?
V-type proton ATPase catalytic subunit A isoform 2, V-ATPase subunit A 2, Vacuolar proton pump subunit alpha 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: RIMM_FLAJ1
Sequence: MRKEECFYLGKIAKKFSFKGEVLIYLDTDEPELYENLESVFVEHNKHLVPFFIETSSLHKGDFLRVRFEDVNTEEDADAIVGNSIYLPLTMLPKLTGNKFYFHEVIGFEIEDKRLGVFGKITSINDSSAQPLFEVLNGEVEILVPMIDHFLVKIDRENKKVIMDLPVGLVEMYL
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNFE_CITK8
Sequence: MSEIKDVIVQGLWKNNSALVQLLGMCPLLAVTSTATNALGLGLATTLVLTLTNLTISALRRWTPAEIRIPIYVMIIASVVSAVQMLINAYAFGLYQSLGIFIPLIVTNCIVVGRAEAFAAKKGPALSALDGFSIGMGATGAMFVLGSMREIIGNGTLFDGADGLLGDWAKVLRVEIFHTDSPFLLAMLPPGAFIGLGLMLAVKYLIDEKMKKRRAEAVAAELPSGETGNV
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit E, Rnf electron transport complex subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IXTPA_ACIB3
Sequence: MSTPHWFDQGSLVLASNNKGKVAEFEKLFEQLKLPVEIIPQGRLNIPDAIEDGLSFIENAIIKARHASKISGKPAMADDSGICVPVLGGAPGIYSARYAGEHGDDAANNAKLLNDLLPFRKNGEAIEGMFVCVLALVTHAEDPLPQIFQGIWHGEILEAPRGENGFGYDPLFWLPELQVSSAELSKEDKNKISHRGQAMQLFRESLQK
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: SYE_PORG3
Sequence: MDTINRRIRVRFAPSPTGPLHIGGVRTALYNYLFARQHGGDMILRIEDTDSNRFVPGAEAYIIEALEWLGIKFDEGVGYGGRFGPYRQSERRDIYRTYVRQLLDSGRAYIAFDTPEELEARRAEVPNFQYDATTRGQMRNSLTLPAEEVERLVAEGTQYVVRFLVEPNVDVEVNDLIRGRVVIDSSILDDKVLYKSADDLPTYHLANIVDDHLMEVSHVIRGEEWLPSAPLHVLLYRAFGWEDTMPRFAHLALLLKPEGNGKLSKRDGDRLGFPVFPLEWKDPQTGDISKGYRESGYLPEAVVNFLALLGWNPGNDQDVMSMDELIRLFDIEKCSKAGAKFDYEKGRWFNHQYIQRKDNAELAELFRPILRENGVVATDEKTAHVISLVKERVNFIGELWEQAGFFFIAPLSYDEKTVKKRWKEDTAKQLGELAELLDSHRSFAAEATEPTVKNWIETNGYHLGNIMNATRLALVGESKGPHIFDIMEVLGREETVGRIRRAIEILG
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.