PharMolix/UniProtQA huggingface dataset:
Protein: TRPB_CAMJD
Sequence: MKKAYYGDFGGQFLPESAMFALNELENAFLKFSKDKFFKKELSELLKTYVGRPTPLYFARNLSKKYQHEIYLKREDLNHTGAHKINNAIAQALLAKKMGKKKIIAETGAGQHGLATATAAALLGLECEIYMGATDVQRQALNVYKMELLGAKIHAVQSGLKTLKEATTAAIQAWVGDIKNIFYVVGSAVGPYPYPKMVTHFQSIIGKECKMQLQKLNKKVDYIIAAVGGGSNAAGIFYDFIKDENVKLIGIEAGGLGVDTLYHAATLNKGETGIIHGMKTKVLQDDLGNILPVHSVSAGLDYPGIGPLHAFLFESKRAQYHAISDEECMQALKLLCKEEGIIAAIESSHALAFLEKLCPTLKKKSVIVINLSGRGDKDMQMIREYKKGVIYG
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: CYP1_BRUMA
Sequence: MSKKDRRRVFLDVTIDGNLAGRIVMELYNDIAPRTCNNFLMLCTGMAGTGKISGKPLHYKGSTFHRVIKNFMIQGGDFTKGDGTGGESIYGGMFDDEEFVMKHDEPFVVSMANKGPNTNGSQFFITTTPAPHLNNIHVVFGKVVSGQEVVTKIEYLKTNSKNRPLADVVILNCGELVRRKKRQHSSRSNESVSSSTSTEKSHKKTKKTKMKEKKRKESDEVEQLEIGTVVPEAELQLSSVKAEDLPDEPDHQNKYLMRRSKTPENSRKGKKEKQRQSPHRFSRRDIGHRLNRMRRTRTGHKIKGRGALRFRTPEGSSDHDGSRTPPHWRREQNRVITLDELHRLQEKRKAYELEELENPKNDVVDKAKTGILLNTSEKIEDKEERYRGKSEKKENRHERSRHTTRRSPEHVTRHFVKEKNRHKVDEVGNSEDMKQTKRDRRGRADEKEKVEVNGEKAAAMDELNLDEPTVEVTLDSAEDIRDSDDEAIRIHLLKAKKMAEEKTKQEAKMLEKTGDKEGRDQKTISEAKQKDSAEKDRQHREHKNDELEKRAIEKQDKDQIVERDTGSKQRRKSDSKEHRGKTDRKHRSKSIEEDGRRSTSREKLDDLKRKETSGQKSQADSEQTVEAKTNVVDSNSDNSKMSVNGKLKEVSSTNKENEVSEQKDLKAESTKSEEIKQQVNEVSRKQKGGEKPKEHKRNERSRSRRRRSRSNGRRRRSSSRRSRSRDRRHKSRSRSRGYVRRFEGWSRSRRPTRRELYDERMRRERERRRSFDRYSDRRRTRSRSARRDSDRHSRRSRKRSPSSSSSSSESSSSDSRSTASSSASSKRSSSSDSSRSSRSRSSN
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase 1, PPIase 1, BmCYP-1, Cyclophilin, Rotamase 1.
Protein: DLG1_HUMAN
Sequence: MPVRKQDTQRALHLLEEYRSKLSQTEDRQLRSSIERVINIFQSNLFQALIDIQEFYEVTLLDNPKCIDRSKPSEPIQPVNTWEISSLPSSTVTSETLPSSLSPSVEKYRYQDEDTPPQEHISPQITNEVIGPELVHVSEKNLSEIENVHGFVSHSHISPIKPTEAVLPSPPTVPVIPVLPVPAENTVILPTIPQANPPPVLVNTDSLETPTYVNGTDADYEYEEITLERGNSGLGFSIAGGTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEVDVRDVTHSKAVEALKEAGSIVRLYVKRRKPVSEKIMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNNVCLEEVTHEEAVTALKNTSDFVYLKVAKPTSMYMNDGYAPPDITNSSSQPVDNHVSPSSFLGQTPASPARYSPVSKAVLGDDEITREPRKVVLHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNAGQAVTIVAQYRPEEYSRFEAKIHDLREQMMNSSISSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPSQGLNFKFGDILHVINASDDEWWQARQVTPDGESDEVGVIPSKRRVEKKERARLKTVKFNSKTRDKGEIPDDMGSKGLKHVTSNASDSESSYRGQEEYVLSYEPVNQQEVNYTRPVIILGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHLYGTSVQSVREVAEKGKHCILDVSGNAIKRLQIAQLYPISIFIKPKSMENIMEMNKRLTEEQARKTFERAMKLEQEFTEHFTAIVQGDTLEDIYNQVKQIIEEQSGSYIWVPAKEKL
What is the function of this protein?
Essential multidomain scaffolding protein required for normal development (By similarity).  Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells.  May play a role in adherens junction assembly, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation.  Regulates the excitability of cardiac myocytes by modulating the functional expression of Kv4 channels.  Functional regulator of Kv1. 5 channel.  During long-term depression in hippocampal neurons, it recruits ADAM10 to the plasma membrane (PubMed:23676497).
What are the official names of this protein?
Disks large homolog 1, Synapse-associated protein 97, SAP-97, SAP97, hDlg.
What is the protein family that this protein belongs to?
Belongs to the MAGUK family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Basolateral cell membrane. Endoplasmic reticulum membrane. Postsynaptic density. Synapse. Cell membrane, sarcolemma. Apical cell membrane. Cell junction. Cytoplasm. Note=Colocalizes with EPB41 at regions of intercellular contacts. Basolateral in epithelial cells (PubMed:12807908). May also associate with endoplasmic reticulum membranes. Mainly found in neurons soma, moderately found at postsynaptic densities (By similarity).
Protein: RT12_PROWI
Sequence: MPTINQLLRKKSSRQAPKLKSKKPALAGCPQKRGVCFRVYTRTPKKPNSALRKVAKIRLCNGIVVIASIPGEGHNLQEHSVVCIRGGRVKDLPGVKYKVVRGRLDLQGVVNRKQSRSLYGTPKSK
What are the official names of this protein?
Ribosomal protein S12, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RSMJ_ECOLU
Sequence: MKICLIDETGTGDGALSVLAARWGLEHDEDNLMALVLTPEHLELRKRDEPKLGGIFVDFVGGAMAHRRKFGGGRGEAVAKAVGIKGDYLPDVVDATAGLGRDAFVLASVGCRVRMLERNPVVAALLDDGLARGYADAEIGGWLQERLQLIHASSLTALTDITPRPQVVYLDPMFPHKQKSALVKKEMRVFQSLVGPDLDADGLLEPARLLATKRVVVKRPDYAPPLANVATPNAVVTKGHRFDIYAGTPV
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCD_RICFE
Sequence: MAIMSDKWIKEAVINQSMIRPFAEKQVRVHNKEKIISYGLSSYGYDARVSNEFKIFTNINSTTVDPKNFSEYNLVDREVDVCIIPPNSFALGRTIEYFKIPRDVLVICVGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTPLPAKIYANEGACQFLFLKSDQICDTSYADRQGKYMKQVGVTLPLT
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: RNY_TREPA
Sequence: MTTSIVIGVVLVTVGLTFGWTIRWLYARFHLSACEQRAERILQEAQKEAESKKKSILLEAKEYVLRERNQQERDDRDRRAELQRAERRLLQKEEALSTRAGELDSRERSLKQRDQSLCQEEARYRQELERVSGLTQNQARDLIIKNLENEAKHDAQALINKIEEDAALNAERRARDILVTTMQRITADVTGDVTVSTVNLPSEEMKGRIIGREGRNIRALETLTGADVVVDDTPEAVVISCFDPVRKEIARISLERLVLDGRIHPARIEEIVQKVTQEVSQKIYEEGEKVLFDLGIHDMCPEGVRALGRLYFRTSYGQNVLYHSKEVALLASMLASEIGADVAIAKRGALLHDIGKGVETDSDRNHAEIGMEMARKMNEDPRVVNAVGSHHNDIEPCCVESWLVQVADAISAARPGARREMVDHYVKRLENLEAIAEGFSGVEKAYAIQAGRELRVLVNNDKIPDRDVKALGRDIAKKIESDLKYPGRIRVTLIRETRVVEYAR
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: CH60_GEOKA
Sequence: MAKQIKFSEEARRAMLRGVDKLADAVKVTLGPKGRNVVLEKKFGSPLITNDGVTIAKEIELEDPFENMGAKLVAEVASKTNDIAGDGTTTATVLAQAMIREGLKNVAAGANPMGIRRGIEKAVAVAVEELKAISKPIKGKESIAQVAAISAADEEVGQLIAEAMERVGNDGVITLEESKGFTTELDVVEGMQFDRGYVSPYMITDTEKMEAVLENPYILITDKKVSSIQELLPVLEQVVQQGRPLLIIAEDVEGEALATLVVNKLRGTFNAVAVKAPGFGDRRKAMLEDIAILTGGEVISEELGRELKSTTIASLGRAAKVVVTKETTTIVEGAGDSERIKARINQIRAQLEETTSEFDREKLQERLAKLAGGVAVIKVGAATETELKERKLRIEDALNSTRAAVEEGIVAGGGTALMNIYNKVAAIEAEGDEATGVKIVLRAIEEPVRQIAQNAGLEGSIIVERLKNEKPGIGFNAATGEWVDMIEAGIVDPTKVTRSALQNAASVAAMVLTTEAVVADKPEENKGNNNMPDMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_TRIV2
Sequence: MTMHNSVEFQDAFDVIVVGAGHSGCEAALATARLGCRTLLLTLNLDKIAWQPCNPAVGGPAKSQLTHEVDALGGEIGKMADRTYLQKRILNSSRGPAVWALRAQTDKREYAAIMKNIVENQENLSIRESMVTDLVLGANDEVIGVETYFGVAFQCKAVILTTGTFLGGKIWVGNKSMPAGRAGEFAAEGLTETLNRLGFETGRLKTGTPARVDKRSVDYSKMQLQPGDEEVRWFSFDPDVWVEREQLPCHMTRTTPETHRLIRENLHLSPVYGGWVEAKGPRYCPSIEDKIVRFVDKESHQIFIEPEGRDIPELYIQGFSTGLPENLQLQMLRSLPGLENCVMLRPAYAVEYDYLPATQCYPTLMTKKVAGLFCAGQVNGTTGYEEAAAQGIVAGINAARFVRDQEMIVFPREQSYLGTLVDDLCTKDLREPYRMLTSRSEYRLLLRSDNSDQRLTPLGREIGLIDDRRWQLFTRKQEQITGEKERLYATRVKENDEVGKAIASNTQQAIKGSITLADLLRRPGFHYVDLDRYGLGNPELTPAEREGAEIDIKYSGYLARQQSQIEQIARQAQRQLPRDLDYTTVETLSKEAREKLNKVKPMTIGQAARIGGVNPADINALLIYLELRQTKHQTGLAALP
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIBB_YERPY
Sequence: MNQTLLSDFGTPVERVERAIDALRNGRGVMVLDDESRENEGDMVFAAEAMTLEQMALTIRHGSGIVCLCITDERRQQLDLPMMVTHNSSQFQTAFTVTIEAAEGVTTGVSAADRLTTIRKAIADNAKPADLNRPGHVFPLRGQPGGVLSRRGHTEASIDLATLAGYKPAGVLCELTNDDGSMAHAPEVIAFAKLHDMPVVTIDDLAAYLQSRAKKAS
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: RS5_BAUCH
Sequence: MVHIEKQISDLQEKLIAVNRVSKTVKGGRIFSFTALTVVGDSNGRVGFGYGKAREVPTAIQKAMDKARRNMTTIVLNSGGTLQHSIKGVHTGSRVFMQPASEGTGIIAGGAMRAVLEVTGIRNVLAKTYGSTNPINVVRATINALNKMKSPEMIAAKRGKTIEEILR
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: ISPE_BURP0
Sequence: MTDTTRSLRDCLAPAKLNLFLHITGRRPDGYHALQSVFQLLDWGDRLHFTLRDDGKVSRVTDVPGVPEESDLVVRAASLLKAHAGATLGVDIEIDKRLPMGAGLGGGSSDAATTLLALNRLWRLDLPRTTLQSLAVKLGADVPFFVFGKNAFAEGIGEALQAVELPARWFLVVTPRVHVPTAAIFSEKSLTRDSKPITITDFLAQRGIDAGWPDSFGRNDMQPVVTSKYAEVAKVVEWFYNLTPARMTGSGASVFAAFKSKADAEAAQAKLPAGWNSAVAESMSEHPLFAFAS
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: CAPA_STAAS
Sequence: MKEKFDLVKLLNILKKNIKLLLILPAICLVVSAALTFFVMPDKYTASTQILVNMKKSSSDLAFQNVQSSLQSVNTYTEIIKSPRILDKVSREFDGQYSTAELNSFLKVTNQTNSQIITVSVTTGNKSESDKIVNKISKVFAHDMPKIMSVDNVTILSSAHDNAVKVSPIVSVNLVISIIVGIVLAILIIFLKELLDKRIKTEEDVESQLGLPILGSIQKF
What is the function of this protein?
Required for the biosynthesis of type 1 capsular polysaccharide.
What are the official names of this protein?
Capsular polysaccharide biosynthesis protein CapA.
What is the protein family that this protein belongs to?
Belongs to the CpsC/CapA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYV_SHIFL
Sequence: MEKTYNPQDIEQPLYEHWEKQGYFKPNGDESQESFCIMIPPPNVTGSLHMGHAFQQTIMDTMIRYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTRHDYGREAFIDKIWEWKAESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRLYKEDLIYRGKRLVNWDPKLRTAISDLEVENRESKGSMWHIRYPLADGAKTADGKDYLVVATTRPETLLGDTGVAVNPEDPRYKDLIGKYVILPLVNRRIPIVGDEHADMEKGTGCVKITPAHDFNDYEVGKRHALPMINILTFDGDIRESAQVFDTKGNESDVYSSEIPAEFQKLERFAARKAVVAAVDALGLLEEIKPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKPAVEAVENGDIQFVPKQYENMYFSWMRDIQDWCISRQLWWGHRIPAWYDEAGNVYVGRNEEEVRKENNLGANVALRQDEDVLDTWFSSALWTFSTLGWPENTDALRQFHPTSVMVSGFDIIFFWIARMIMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEGQKMSKSKGNVIDPLDMVDGISLPELLEKRTGNMMQPQLADKIRKRTEKQFPNGIEPHGTDALRFTLAALASTGRDINWDMKRLEGYRNFCNKLWNASRFVLMNTEGQDCGFNGGEMTLSLADRWILAEFNQTIKAYREALDSFRFDIAAGILYEFTWNQFCDWYLELTKPVMNGGTEAELRGTRHTLVTVLEGLLRLAHPIIPFITETIWQRVKVLCGITADTIMLQPFPQYDASQVDEAALADTEWLKQAIVAVRNIRAEMNIAPGKPLELLLRGCSADAERRVNENRGFLQTLARLESITVLPADDKGPVSVTKIIDGAELLIPMAGLINKEDELARLAKEVAKIEGEISRIENKLANEGFVARAPEAVIAKEREKLEGYAEAKAKLIEQQAVIAAL
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AHPC_STAES
Sequence: MSLINKEILPFTAQAYDPKKDEFKEVTQEDFKGSWNVVCFYPADFSFVCPTELEDLQNQYAKLQELGVNVYSVSTDTHFVHKAWHDHSDAISKLEYSMIGDPSQTITRNFDVLDEESGLAQRGTFIIDPDGVVQAAEINADGIGRDASTLVNKIKAAQYVRQHPGEVCPAKWEEGSESLQPGLDLVGKI
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Alkyl hydroperoxide reductase C, Peroxiredoxin, Thioredoxin peroxidase.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WTF20_SCHPO
Sequence: MKNNYTSLKSPLDEEDELKTDHEIDLEKGLLPEYNSEEEGALPPYSDISKLANPVPEDSSTGPTEIANPNVERRQEFKDSHPNIYFLLRLLISVLAVSVVFFTAWVCVNPLEKSIFGKVAFSVTIGITCPILFIAIFYFYETWTKACGKGIKHFLKKWRNMFFTFCKSPIFCLVLLKAENKLSSHLGDQQWGWKCSASAFTFMAVSSILIFIAETVEPGSCSTDLVKRVQAYCDYEARQYASSNTAIPLREMNPENEA
What is the function of this protein?
Acts as a suppressor component of the dual wtf meiotic drive system, and can suppress but not confer meiotic drive by compatible poisons (By similarity).  Wtf meiotic drive systems promote unequal transmission of alleles from the parental zygote to progeny spores by encoding a poison and an antidote from the same locus; the poison is trans-acting and forms toxic aggregates in all spores within an ascus, wherease the antidote is spore-specific and targets aggregates for degradation by the vacuole (By similarity).  Meiotic drive by wtf systems therefore lead to poisoning of all progeny that do not inherit the dual poison/antidote allele, or express a compatible antidote (By similarity).
What are the official names of this protein?
Meiotic drive suppressor wtf20.
What is the protein family that this protein belongs to?
Belongs to the WTF family.
What are the subcellular locations of this protein?
Spore membrane; Multi-pass membrane protein. Vacuole membrane; Multi-pass membrane protein.
Protein: NUD17_XENTR
Sequence: MESAKRVLVCLTKENSLLQCAKFVQGITGQYSANNGDKALIHCGLDRNQFVISDRQFPSSAPVQLQRPSFCPIKNLSPTQAAALPGEIRNRGVDVGVAVLVQSVNKKVLLTRRSKSLNIFPNVWVPPGGHVEPGEQLLEAGLRELREETGLRLQGVPWCMLGLWESAFPPLLSQGLPSRHHIVTYLLVQSNQTHQQLQERLCPDEREVSACVWLDTEIAKCIVAAEDDAKDSGKPQGPAPATIRVSELINGSLSQSDRSMATFLSTAPKEGEAVERISTGTKYALSLWLETLPKAPSREHE
What is the function of this protein?
Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.
What are the official names of this protein?
Nucleoside diphosphate-linked moiety X motif 17, Nudix motif 17.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
Protein: NU5M_CANAL
Sequence: MQLLYYIYEEPVTIHLGTWISLGDIVIPFGLSLDSLAMTVIVPVGIITLCVLAYAIEYMSHDPNRNRFYIILSIFAVFMTILVVSDNYLMMFIGWEFVGVISYLLISFWSTRITAMKSALSAILLNRMGDTFFVIALGLMINYYHAVDYDTIALVTPYMNTFLLNTLGLLLLLAATAKSAQLGLHAWLLQAMEGPTPVSALLHAATMVCAGVYVLVRSYMILEYTPTMLLIICWLGGLTTLVSGLIAIVTNDIKRVIALSTMSQLSIMVLAIGISAYDLAIYHLYCHAFFKALLFMGAGSVIHSFVAESQDMRKYGGLIEYLPFSYTAILIASLSLMAIPGLTGYYSKDIIIESLYGSYTLSGYILYYIAVGSATLTSIYSLRVLYLTFMGVPNANKASYSHIHESLGMMIPMIVLVIYSIFIGYSRDSVIGHYALSLPANNGFIETEYTLPAYIKLLPLILGLTLSAILVYVYEYAYKINRSAVYDYLNNRIYYEQILNNIVIRNTLRLGGYMNAYIDQGLLKVLGSTGVSRAVTYINVIVIINILYLFFI
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 5, NADH dehydrogenase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: HSCB_SHESA
Sequence: MNYFELFKFSPAFDIDTAVLAERYRELQRAVHPDKFANDTEQQRLLSVQRTAQVNDGYQTLKDPIRRAEHMLSLRGIDLSHETTTVKDTAFLMQQMEWREALEDIRDSADPQESIDELYDSFAAYRTKLTKLLTAQLSSGSEDDALLAADQVRKLKFMAKLHDELTRIEDALLD
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB homolog.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: FXL19_HUMAN
Sequence: MGMKVPGKGESGPSALLTPPMSSSSRGPGAGARRRRTRCRRCRACVRTECGDCHFCRDMKKFGGPGRMKQSCLLRQCTAPVLPHTAVCLLCGEAGKEDTVEGEEEKFGLSLMECTICNEIVHPGCLKMGKAEGVINAEIPNCWECPRCTQEGRTSKDSGEGPGRRRADNGEEGASLGSGWKLTEEPPLPPPPPRRKGPLPAGPPPEDVPGPPKRKEREAGNEPPTPRKKVKGGRERHLKKVGGDACLLRGSDPGGPGLLPPRVLNPSQAFSSCHPGLPPENWEKPKPPLASAEGPAVPSPSPQREKLERFKRMCQLLERVPDTSSSSSDSDSDSDSSGTSLSEDEAPGEARNGRRPARGSSGEKENRGGRRAVRPGSGGPLLSWPLGPAPPPRPPQLERHVVRPPPRSPEPDTLPLAAGSDHPLPRAAWLRVFQHLGPRELCICMRVCRTWSRWCYDKRLWPRMDLSRRKSLTPPMLSGVVRRQPRALDLSWTGVSKKQLMWLLNRLQGLQELVLSGCSWLSVSALGSAPLPALRLLDLRWIEDVKDSQLRELLLPPPDTKPGQTESRGRLQGVAELRLAGLELTDASLRLLLRHAPQLSALDLSHCAHVGDPSVHLLTAPTSPLRETLVHLNLAGCHRLTDHCLPLFRRCPRLRRLDLRSCRQLSPEACARLAAAGPPGPFRCPEEKLLLKDS
What is the function of this protein?
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex (By similarity).  Binds to DNA containing unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides (PubMed:29276034).
What are the official names of this protein?
F-box/LRR-repeat protein 19, F-box and leucine-rich repeat protein 19.
Protein: PYRH_XANOR
Sequence: MSELSYRRILLKLSGEALMGDGDYGIDPKVINRLAHEVIEAQQAGAQVALVIGGGNIFRGAGLAASGMDRVTGDHMGMLATVINALAMQDALEKLGAKVRVMSAIKINDVCEDFIRRRAIRHLEKGRIAIFAAGTGNPFFTTDSGAALRAIEIGADLLLKATKVDGVYDKDPKKHTDAVRYDSLTYDQVIMQDLEVMDTAAFALARDSDLPLRIFGMSEPGVLLRILHGEQIGTLVQGRS
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_ANAPZ
Sequence: MIFNVLTIFPQMFPGPLGVSNLGSALKKGLWTLNVFDIRAFANNKHNTVDDTPYGGGPGMLLRADVLGRCIDEVLSLHPNTKLMFTSPRGVSFTQDIARQTMNFDNITLLCGRFEGIDERVVDFYKLQEVSIGDYVLSGGELAAMVIIDTCVRMVPGVIGNAESLKQESMEGSLEYPQYTRPASWKGMEVPEVLLTGNHGEIEKWRRNASLSITAARRPDLLKDRYGENDVE
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHLB_XANCP
Sequence: MSDKPLTDLTFSSFDLHPALVAGLESAGFTRCTPIQALTLPVALPGGDVAGQAQTGTGKTLAFLVAVMNRLLIRPALADRKPEDPRALILAPTRELAIQIHKDAVKFGADLGLRFALVYGGVDYDKQRELLQQGVDVIIATPGRLIDYVKQHKVVSLHACEICVLDEADRMFDLGFIKDIRFLLRRMPERGTRQTLLFSATLSHRVLELAYEHMNEPEKLVVETETITAARVRQRIYFPSDEEKQTLLLGLLSRSEGARTMVFVNTKAFVERVARTLERHGYRVGVLSGDVPQKKRESLLNRFQKGQLEILVATDVAARGLHIDGVKYVYNYDLPFDAEDYVHRIGRTARLGEEGDAISFACERYAMSLPDIEAYIEQKIPVEPVTTELLTPLPRTPRATVEGEEVDDDAGDSVGTIFREAREQRAADEARRGGGRSGPGGASRSGSGGGRRDGAGADGKPRPPRRKPRVEGEADPAAAPSETPVVVAAAAETPAVTAAEGERAPRKRRRRRNGRPVEGAEPVVASTPVPAPAAPRKPTQVVAKPVRAAAKPSGSPSLLSRIGRRLRSLVSGS
What is the function of this protein?
DEAD-box RNA helicase involved in RNA degradation.  Has RNA-dependent ATPase activity and unwinds double-stranded RNA.
What are the official names of this protein?
ATP-dependent RNA helicase RhlB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. RhlB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HYPA_CHLTE
Sequence: MHEMSIAMSVVEAVVDKAREEGGGKITGIDLVVGRLAGVEVESLKFCFGAAARGTLAEGAELVIEEPEGRGRCEACGAEFPVTSFYAKCSACGQFRVKIESGRELAVRSFTIE
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: CCME_YERE8
Sequence: MNPRRKSRLYLAVVVLIGIGLTTTLVLYALRSNIDLFYTPGEILQGKGERHEKPEIGQRLRIGGMVMPGSVKRDDKTLEMSFKVYDARGAVTVTYTGILPDLFREGQGVVAQGVFAEGNTINAKEVLAKHDEKYTPPEVKEAMKENHTRPAEAYNSTAAQGNAS
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: NU4LC_NOSS1
Sequence: MQLRYFLLLAAALFCIGIYGLITSRNAVRVLMSIELLLNAVNLNLMAFSNYLDSTLIKGQVFTVFVITVAAAEAAVGLAIVLAIYRNRDTVDMEQFNLLKW
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 4L, NAD(P)H dehydrogenase subunit 4L, NADH-plastoquinone oxidoreductase subunit 4L, NDH-1, subunit 4L, NDH-E.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: RPIA_STRP6
Sequence: MKALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRVKQEGLQVVGVTTSSVTSKQAEGLGIPLKSIDDIDSIDLTVDGADEVDKDFNGIKGGGAALLMEKIVATPTKEYIWVVDASKMVEHLGAFKLPVEVVQYGADRLFRVFEKAGYKPSFRMKGDSRLVTDMQNYIIDLDLGCIKDPVAFGHLLDGTVGVVEHGLFNGMVDKVIVASKDGVTVLEAPKAG
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.