PharMolix/UniProtQA huggingface dataset:
Protein: RUVA_DESAP
Sequence: MIDFLKGRLVSVYPEAVVVEVGGIGYRVQVPPSLAASLPEPGETVFLYTYLSVKETALEMFGFSSELDRTAFLLLLGVAGIGPRTALAVVGRLGTRRLWAAILREDTGILTTVPGIGVKSARRIMVELRDRLEKQQVAVSAELPASDGVPVLAGRAENEALAALISLGYTPREAREALNRLPDRKLDAAGLVHAALRIMGSQ
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: UBIQP_PEA
Sequence: MQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGF
What is the function of this protein?
Ubiquitin exists either covalently attached to another protein, or free (unanchored).  When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains).  Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involved in protein degradation via the proteasome.  Linear polymer chains formed via attachment by the initiator Met lead to cell signaling.  Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed.  When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling (By similarity).
What are the official names of this protein?
Polyubiquitin.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: AGRB_STAA3
Sequence: MNYFDNKIDQFATYLQKRNNLDHIQFLQVRLGMQVLAKNIGKLIVMYTIAYILNIFLFTLITNLTFYLIRRHAHGAHAPSSFWCYVESIILFILLPLVIVNFHINFLIMIILTVISLGVISVYAPAATKKKPIPVRLIKRKKYYAIIVSLTLFIITLIIKEPFAQFIQLGIIIEAITLLPIFFIKEDLK
What is the function of this protein?
Essential for the production of a quorum sensing system signal molecule, the autoinducing peptide (AIP).  This quorum sensing system is responsible for the regulation of the expression of virulence factor genes.  Involved in the proteolytic processing of AgrD, the precursor of AIP.
What are the official names of this protein?
Accessory gene regulator protein B.
What is the protein family that this protein belongs to?
Belongs to the AgrB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL29_BURM1
Sequence: MKASELLQKDQAALNKELADLLKAQFGLRMQLATQQLTNTSQLKKVRRDIARVRTVMTQKANQK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: NARF_DROVI
Sequence: MSRFSGALQLTDLDDFITPSQECIKPVMIDKTKSKTGAKITVQADGYYEQSESGKQKLQKVEITLQDCLACSGCITSAEGVLITQQSQEELLKVLRENQTLKASGDNDQVRTIVFTISVQPLLSLAHRYDLGVEEASRYLAGYLRQLGADYVLCTKIADDLALLECRQEFVERFRDNAELSMLSSSCPGWVCYAEKTHGNFILPHIATTRSPQQIMGVLVKQLLAEKLGVPGSRIYHATIMPCYDKKLEASREDFYSEVNGSRDVDCVITSIEVEQMLQAEEQTLQQFEPSDIDWPWTDQQPEFPVWAHEATMSGGYAEHIFKYAAKELFSEETPNELQFKALRNRDFSEISLEKDGKTVLKFAIANGFRNIQNLVQKLKRGKGPGYHFVEVMACPSGCINGGAQVRPTTGQHVRELTQQLEELYKQLPRSNPDNSYTKQIYTDFLDGAHTDKSLELLHTSYHAVEKLNTALNIKW
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery.  Required for maturation of extramitochondrial Fe/S proteins (By similarity).
What are the official names of this protein?
Probable cytosolic Fe-S cluster assembly factor GJ13047.
What is the protein family that this protein belongs to?
Belongs to the NARF family.
Protein: Y2848_SHEB9
Sequence: MNKDDDKEGLAMFSALIDGIKPITQNKRHFRTPLKTKQEIELKEQQLHANSYFSDTYQPLLPVQGPMRWLEEGIDSLELKRLRRGDYQPDLLLDLHGYRQSEAKLELAALIQACVKQQSLCCCIMHGYGSGILKQQVPMWLVQHPMVKAFHQAPKEWGGDAALLVLIDIGEQPHRR
What are the official names of this protein?
UPF0115 protein Sbal195_2848.
What is the protein family that this protein belongs to?
Belongs to the UPF0115 family.
Protein: Y294_SYNY3
Sequence: MFLEELKPVTRELCQQPIAFAGGFVSGVLRLKLTDDPLKKWLQKQGVTDFSGADINQTAQDNRPQSIDID
What are the official names of this protein?
UPF0426 protein ssl0294.
What is the protein family that this protein belongs to?
Belongs to the UPF0426 family.
Protein: ORN_COREF
Sequence: MSETVGNGENFPAVAARDDRLVWVDLEMTGLDLERHVIVEVAALVTDANLNILGEGVDLVVHATDEELARMDDFVTRMHDSSGLTPLIRASTVSLKDAEDAVLALIEEHCDPAHPAPLAGNSIATDRAFIREQMPRLDAALHYRMVDVSSVKELARRWCPRVYYKQPTKGLAHRALADIVESIRELDYYRRSFFVADPGPTSAQCEADAETSVARFAHYLE
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIGAR_XENLA
Sequence: MARFALTIVRHGETRYNKEKLLQGQGIDEPLSEMGFKQADAAGRFLSNVRFTHVFSSDLIRAKQTACAIMRNNQLSEDIKIMYDPRLRERKYGDAEGRPLSELKVMAKKAGGQCPSYTPPGGETLEQVRACAKDFFEYLCQLVMAESSVKEKSELGASGMVGIMSTDLAPFVNHNKEPTIFGESRDVTLDASVLLVSHGAYMRNWIKYFVEDLQFTFPPELKKSRELSVSPNTGISHFIVTVGSGATRKPEIQCVCINLHGHLSDIDADTSHYQV
What is the function of this protein?
Fructose-bisphosphatase hydrolyzing fructose-2,6-bisphosphate as well as fructose-1,6-bisphosphate.  Acts as a negative regulator of glycolysis by lowering intracellular levels of fructose-2,6-bisphosphate in a p53/TP53-dependent manner, resulting in the pentose phosphate pathway (PPP) activation and NADPH production.  Contributes to the generation of reduced glutathione to cause a decrease in intracellular reactive oxygen species (ROS) content, correlating with its ability to protect cells from oxidative or metabolic stress-induced cell death.  May play a role in mitophagy inhibition.
What are the official names of this protein?
Fructose-2,6-bisphosphatase TIGAR, TP53-induced glycolysis and apoptosis regulator.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion.
Protein: FCPC_PHATR
Sequence: MKTAVIASLIAGAAAFAPAKNAARTSVATNMAFEDELGAQPPLGFFDPLGLVADGDQEKFDRLRYVEIKHGRISMLAVVGYLVQEAGVRLPGTIDYSGKTFAEIPKFAAFKEIPAGGLVQLLFFIGVLESSVMRDLTGEAEFVGDFRNGAIDFGWDTFDEETQFKKRAIELNQGRAAQMGILAFMVHEQLGVSLLPQ
What is the function of this protein?
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.  Energy is transferred from the carotenoid and chlorophyll C (or B) to chlorophyll A and the photosynthetic reaction centers where it is used to synthesize ATP and reducing power.
What are the official names of this protein?
Fucoxanthin-chlorophyll a-c binding protein C, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the fucoxanthin chlorophyll protein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein. Note=FCPs are probably transported across the endoplasmic reticulum membranes that surround the plastid via a signal peptide, followed by translocation across the thylakoid membrane via a transit peptide.
Protein: PAN2_EMENI
Sequence: MEADWNELLRIPLPPPNPHGLPTVATTIAFDDVSELLWAGNEYGRITSFYGPELQRYTSVRAHPVAEGPVRQILFHERGVISISSRSVHMITRRGLTQWHITHDEITDLRCMSFTAQTNKIIVAGCQKAMFTIDIDKGTIVDKLRTEHNYVLMKRSRYLCAATDTGSVNALSLTDFSVVKSWKAHGAAVNDMDARGDLLVTCGFSIRQTGSPIVDPLANVYDLKTLSPLPPIPFHAGAAYVRMHPKLQTTSFVASQSGQLQVVDLMNPNAFKLRQATVSFMLGIEISPSGEALAINDAECFIQLWGSPAKIHFNEMSKEVEFADVTPRPPQVDWSPEIPLNVIGMPYYHERLLSAWPSHLLFEVGSPPAPIDPSIVPYLRSGEMGQYAANPKKTRRYQVENTRALASTEPTLIAPKFLSEKAREQSKKADDPVGDTAASLAGARISGESEDDPLLKYSNVEIKYSRFGVDDFDFRFYNQTCFSGLETHIANSFTNSLLQLLKFIPLIRNIALHHAATSCIAESCLLCEMGYLFDMLEKANGQNCQATNLLKTFSSFREASNLGLLEENLTNKSLSSAIQAVNRFFLGQIAQDYRRIAPNSEELDMRLATIASESIRCMFCQNEIVRPGNTLVNELMYPAIDMKQARRNHTLRFSNILRASIEREAQNRGWCHICRRYQQSVMRKTAHRMPHVLMLNAAINSPACRRLWTIPGWLPEEIGIVLEGGQVLCFEGEDLRMRIQGQMPGLIIYDLVGLVAEINIPEHQKAHLVSFINVSVSSRERETRSKWHLFNDFLVTEVDKEEALRFNQSWKSPCVLAFQVRDARHMVDDTWKNFLDTTLLFRDWSLNNGRPVESRVMLSDEEKPTPGTPVALDTEFVDLEKAEINVKADGSQEIVRPSKSGLARVSVLRGSGEREGVPFIDDYISVKEPIVDYVTQYSGIKPGDLDPRTSPHNIVPLKVAYKKLWLLLNLGCVFVGHGLASDFRKVNIQVPKKQTVDTQYLFFHPSKNRRLSLRYLAWAVFKEYIQEEPADSNQGHDSIEDARMALRLWKKFQEYEDAGIVGQILEEIFREGSKLGFRPPPRNGVTTVLSRPGTAVTMQNNSGRNTPSTPDVGAAASAPTTPRQAFRRSIALTPSNGTFSGPGSGEFFTGSPLK
What is the function of this protein?
Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover.  PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein pab1.  PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex.  Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by xrn1.  May also be involved in post-transcriptional maturation of mRNA poly(A) tails.
What are the official names of this protein?
PAN2-PAN3 deadenylation complex catalytic subunit pan2, PAB1P-dependent poly(A)-specific ribonuclease, Poly(A)-nuclease deadenylation complex subunit 2, PAN deadenylation complex subunit 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. PAN2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_THET2
Sequence: MAKKPSKKKVKRQVASGRAYIHASYNNTIVTITDPDGNPITWSSGGVIGYKGSRKGTPYAAQLAALDAAKKAMAYGMQSVDVIVRGTGAGREQAIRALQASGLQVKSIVDDTPVPHNGCRPKKKFRKAS
What is the function of this protein?
Located on the upper part of the platform of the 30S subunit, where it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity).
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: BGA12_ARATH
Sequence: MGLNFREKAWILLGILCCSSLICSVKAIVTYDRKAVIINGQRRILLSGSIHYPRSTPEMWPDLIQKAKDGGLDVIQTYVFWNGHEPSPGQYYFEDRYDLVKFIKVVQQAGLYVHLRIGPYVCAEWNFGGFPVWLKYVPGMVFRTDNEPFKAAMQKFTEKIVRMMKEEKLFETQGGPIILSQIENEYGPIEWEIGAPGKAYTKWVAEMAQGLSTGVPWIMCKQDDAPNSIINTCNGFYCENFKPNSDNKPKMWTENWTGWFTEFGGAVPYRPAEDIALSVARFIQNGGSFINYYMYHGGTNFDRTAGEFIATSYDYDAPLDEYGLPREPKYSHLKRLHKVIKLCEPALVSADPTVTSLGDKQEAHVFKSKSSCAAFLSNYNTSSAARVLFGGSTYDLPPWSVSILPDCKTEYYNTAKVQVRTSSIHMKMVPTNTPFSWGSYNEEIPSANDNGTFSQDGLVEQISITRDKTDYFWYLTDITISPDEKFLTGEDPLLTIGSAGHALHVFVNGQLAGTAYGSLEKPKLTFSQKIKLHAGVNKLALLSTAAGLPNVGVHYETWNTGVLGPVTLNGVNSGTWDMTKWKWSYKIGTKGEALSVHTLAGSSTVEWKEGSLVAKKQPLTWYKSTFDSPTGNEPLALDMNTMGKGQMWINGQNIGRHWPAYTARGKCERCSYAGTFTEKKCLSNCGEASQRWYHVPRSWLKPTNNLVIVLEEWGGEPNGISLVKRTAK
What are the official names of this protein?
Beta-galactosidase 12, Lactase 12.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 35 family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: RL1_CLOK1
Sequence: MKLGKKYKESTKLIDRKTLYTPLEAMELALKTAKANFDETIELSIKLGVDPRHADQQVRGAVVLPHGTGKKVRVLVLAKGDRIKEAEDAGADYVGAEEYVEKIQKENWFDFDVVVATPDMMGVVGRLGRILGPKGLMPNPKSGTVTFDVAKAIQEIKAGKVEYRVDKTSIVHVPIGKKSFEVQKLLDNFRVLMEAIIKAKPSAAKGQYLKSVAVSSTMGPGIKINSVKVLE
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: OGG1_METTH
Sequence: MRIPVGDFDLEMTQRSGQTSQPPWREVEGAFRELLIIEGVPCPVEVRNEAGVLRVRPYVDVPQKTLREKIEYIFDLKFDIEDFYTFLEDKNLSYTLDSSRGLRLFLAKDPFECVISSIASANCSVVRWTRSIEDIRRLWGQANTFNGETFHTFPSPHVLTGVAEGSLEDLQRAEDNLPSDFSFNDLRSCGVGYRAPYIRETSRILAEEMDIRRIDGMDYDDARELLLELSGVGPKVADCILLYGFRKTEAFPVDVWIRRIMNHIHPGRNFNDRSMVEFARREYGEMADYVQLYLFNHARRSGLLDRLRQGTG
What is the function of this protein?
DNA repair enzyme that incises DNA at 8-oxoG residues.  Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA.  Has a beta-lyase activity that nicks DNA 3' to the lesion (By similarity).
What are the official names of this protein?
Probable N-glycosylase/DNA lyase.
What is the protein family that this protein belongs to?
Belongs to the type-1 OGG1 family.
Protein: NELFB_MOUSE
Sequence: MFAGLQDLGVANGEDLKETLTNCTEPLKAIEQFQTENGVLLPSLQSALPFLDLHGTPRLEFHQSVFDELRDKLLERVSAIASEGKAEERYKKLEDLLEKSFSLVKMPSLQPVVMCVMKHLPKVPEKKLKLVMADKELYRACAVEVKRQIWQDNQALFGDEVSPLLKQYILEKESALFSTELSVLHNFFSPSPKTRRQGEVVQKLTQMVGKNVKLYDMVLQFLRTLFLRTRNVHYCTLRAELLMSLHDLDVSDICTVDPCHKFTWCLDACIRERFVDSKRARELQGFLDGVKKGQEQVLGDLSMILCDPFAINTLSLSTIRHLQELVSQETLPRDSPDLLLLLRLLALGQGAWDLIDSQVFKEPKMEAELITKFLPMLMSLVVDDFTFNVDQKLPAEEKASVTYPNTLPESFTKFLQEQRMACEVGLYYVLHITKQRNKNALLRLLPGLVETFGDLAFSDIFLHLLTGSLVLLADEFALEDFCSSLFDGFFLTASPRKENVHRHVLRLLLHLHARVAPSKLEALQKALEPTGQSGEAVKELYSQLGEKLEQLDHRKPSPTQAAETPALDLPLPSVPAPATL
What is the function of this protein?
Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II (Pol II) (PubMed:25773599).  The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex (By similarity).  May be able to induce chromatin unfolding (By similarity).  Essential for early embryogenesis; plays an important role in maintaining the undifferentiated state of embryonic stem cells (ESCs) by preventing unscheduled expression of developmental genes (PubMed:19340312).  Plays a key role in establishing the responsiveness of stem cells to developmental cues; facilitates plasticity and cell fate commitment in ESCs by establishing the appropriate expression level of signaling molecules (PubMed:25773599).  Supports the transcription of genes involved in energy metabolism in cardiomyocytes; facilitates the association of transcription initiation factors with the promoters of the metabolism-related genes (PubMed:24656816).
What are the official names of this protein?
Negative elongation factor B, NELF-B, Cofactor of BRCA1.
What is the protein family that this protein belongs to?
Belongs to the NELF-B family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ZN777_HUMAN
Sequence: MENQRSSPLSFPSVPQEETLRQAPAGLPRETLFQSRVLPPKEIPSLSPTIPRQGSLPQTSSAPKQETSGRMPHVLQKGPSLLCSAASEQETSLQGPLASQEGTQYPPPAAAEQEVSLLSHSPHHQEAPVHSPEAPEKDPLTLSPTVPETDMDPLLQSPVSQKDTPFQISSAVQKEQPLPTAEITRLAVWAAVQAVERKLEAQAMRLLTLEGRTGTNEKKIADCEKTAVEFANHLESKWVVLGTLLQEYGLLQRRLENMENLLKNRNFWILRLPPGSNGEVPKVPVTFDDVAVHFSEQEWGNLSEWQKELYKNVMRGNYESLVSMDYAISKPDLMSQMERGERPTMQEQEDSEEGETPTDPSAAHDGIVIKIEVQTNDEGSESLETPEPLMGQVEEHGFQDSELGDPCGEQPDLDMQEPENTLEESTEGSSEFSELKQMLVQQRNCTEGIVIKTEEQDEEEEEEEEDELPQHLQSLGQLSGRYEASMYQTPLPGEMSPEGEESPPPLQLGNPAVKRLAPSVHGERHLSENRGASSQQQRNRRGERPFTCMECGKSFRLKINLIIHQRNHIKEGPYECAECEISFRHKQQLTLHQRIHRVRGGCVSPERGPTFNPKHALKPRPKSPSSGSGGGGPKPYKCPECDSSFSHKSSLTKHQITHTGERPYTCPECKKSFRLHISLVIHQRVHAGKHEVSFICSLCGKSFSRPSHLLRHQRTHTGERPFKCPECEKSFSEKSKLTNHCRVHSRERPHACPECGKSFIRKHHLLEHRRIHTGERPYHCAECGKRFTQKHHLLEHQRAHTGERPYPCTHCAKCFRYKQSLKYHLRTHTGE
What is the function of this protein?
May be involved in transcriptional repression (PubMed:31856708).  Inhibits cell proliferation through CDKN1A/p21 induction by down-regulation of NIBAN1/FAM129A at low cell density (PubMed:25560148).
What are the official names of this protein?
Zinc finger protein 777.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HEM1_HELAH
Sequence: MELETTKYFILAFTHKSMSLEMREKLAINSPAILKEFLQTIKNYCPNIKECMVLSTCNRFEIYASLKHNTHADEQKNALLKILAQNKKMSVSDLEKCVLMSTDESAVHHVFSVCSSLDSLVVGETQITGQMKNAYKFAFEEKFCSKDLTRLLHFAFKCAAKVRNLTGISKQGVSISSVAVKEALSIFEKEKIEDKKALVIGLGEMSQLVIKHLLNKQFEVLVLGRNAAKFEDFLKELEEPKKVSFQNIENLNAYINAYELLFCATSSPNFIVQNCMVKETIFRRFWFDLAVPRNIEKPIFNNIFLYSVDDLEPMVRENVENRQESRMKAYEIVGLATMEFYQWIQSLEVEPLIKDLRELARISAQKELQKAVKKRYVPKEYESNIEKILHNAFNAFLHHPTIALKKNAQKEESDVLVGTIKNLFNLDKSSTNHAQNLNLYKCEYYEE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: RL28_RUTMC
Sequence: MAKVCVVTGKRPISGNNVSHANNRTRRRFYPNLHTHRFWVENENRFVKLKLSAKGLRIIDKKGIDTVLAKIRIRGEKV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: PRP1_SALTY
Sequence: MMRPEEIYQRIEAKNWRHVWVVGDIHGCFSMLMKRLRECRFDPQQDLLVSVGDLIDRGPDSLGCLALLRESWMTAVRGNHEQMALDARASSQSTLWLMNGGDWFTRLTAEHAAQAEALFILCQRLPWILEVRCRHSTHVIAHADYPASTYQWQKKVDLHQVLWSRERLINKRGGISGADHFWFGHTPLRRRMDFANVHYIDTGAVFGGQLTLARIQ
What is the function of this protein?
Can hydrolyze phosphorylated Ser-, Thr- or Tyr-substrates in vitro.  The natural substrate is unknown.
What are the official names of this protein?
Serine/threonine-protein phosphatase 1.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-1 subfamily.
Protein: NUSB_YERE8
Sequence: MKPAARRRARECAVQALYSWQLSKNDIADVELQFLSEQDVKDVDIAYFRELLSGVAVNAASLDALMAPVLSRQLEELGQVERAVLRIALFELSKRDDVPYKVAINEAIELAKTFGAADSHKFVNGVLDKVAPTVRKRK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: FABZ_BACC2
Sequence: MLNIEQIKEIIPHRYPFLLVDKILEVDEGKRAVGIKNVSANEEFFNGHFPDYAVMPGVLIVEALAQVGAVAVLKKEENRGRLAFFAGIDNCRFKKQVRPGDQLRLEVEMTRVRGPIGKGKAIATVDGEVACEAEITFAIGDKKE
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCD_SALPB
Sequence: MSWIERIKSNITPTRKASIPEGVWTKCDSCGQVLYRAELERNLEVCPKCDHHMRMSARNRLHSLLDEGSLVELGSELEPKDVLKFRDSKKYKDRLASAQKETGEKDALVVMKGTLHGMPVVAAAFEFAFMGGSMGSVVGARFVRAVEQALEDNCPLVCFSASGGARMQEALMSLMQMAKTSAALAKMQERGLPYISVLTDPTMGGVSASFAMLGDLNIAEPKALIGFAGPRVIEQTVREKLPPGFQRSEFLIEKGAIDMIVRRPEMRLKLASILAKLMNLPAPNPDAPREGVVVPPAPDQESEA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SK_SOLLC
Sequence: MEARVSQSLQLSSWINSDKVVRKPSGLLRFSEKWNEKPRHRVVVSCHLQPRKAAHSDRRVQLKVSCSPQNVQASVLESGCFSASIDEIETLKNKAEEVEEYLDGRCVYLVGMMGCGKTTVGRILAETLGYSFFDCDRLIEQAVGGITVAEIFELRGESFFRDNETEVLHKLSLMHRLVVSTGGGAVVRPINWRHMHKGISVWLDVPLEALAKRITTEGTKSRPLLHEESGDVYDTTLKRLTTLMETRGENYANASARVSLENIALKREKDVCHITPAEITLEVLIQIENFLKTQKSVVVL
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SL4_ECHPL
Sequence: MGRFIFVSFSLLVVFFSLSGTEAGVCCPLGWSGYDQNCYKAFEELMNWADAEKFCTQQHKGSHLVSLHNIAEADFVVKKIVSVLKDGVIWMGLNDVWNECNWGWTDGAQLDYKAWNVESNCFIFKTAENHLVTYGLQWDTQFRLQEPG
What is the function of this protein?
Interferes with one step of hemostasis (modulation of platelet aggregation, or coagulation cascade, for example).
What are the official names of this protein?
Snaclec 4, C-type lectin 4, CTL-4.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1770_STRA1
Sequence: MMNMQNMMRQAQKLQKQMEQKQADLAASQFTGKSAQELVTVTFTGDKKLISIDYKEAVVDPEDIETLQDMTTQAINDALSQVDDATKKIMGAFAGKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein SAK_1770.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: CYB_CYNLU
Sequence: MTNTRKTHPLIKIINHSFIDLPAPSNISAWWNFGSLLGLCLAIQILTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGLYYGSYTYFETWNIGVVLLFVVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFVLPFIVAALVMVHLLFLHETGSNNPSGLISDSDKIPFHPYYTIKDXLGVLLLIMALMILVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILMLFPLLHVSKQRSMMFRPLSQCVFWFLVADLLTLTWIGGQPVEHPFIIIGQLASMLYFTIMLLMLPTVSLIENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.