PharMolix/UniProtQA huggingface dataset:
Protein: RPOB_FRATO
Sequence: MSYSYAEKKRIRKEFGVLPHILDVPYLLSIQTESYKKFLTVDAAKGRLHSGLEIVLKQSFPVESKNGQYELHYVDYQIGEPTFDETECQVRGATYDAPLNVKLRLVVYNKDALPNEKIVEDIREEYVYMGDIPLMTTNGTFIINGTERVVVSQLHRSPGVFFSKDDSEEGAFSARIIPYRGSWLDFEFDSKGIIWARIDRKRKFCATVILKALGYTQEQILENFSESKTITFNSKGFALRLDNLSNMKGELLKFDIVDAQDNVIVKKNKKLTSRDVKKIKDAGVDSVAIDFDLVSTLRVAKDIVNEATGEVIAYANDDVTESLLESCVEVGMLELEVIDFITTERGRYISDTLKYDLTRNTDEALVEIYKVLRPGDPPAAASVKALFEGLFFIESRYSLSDIGRMKLNARLGSDKVSKDIYTLENSDIVGVIEELINIRDGKGKVDDIDHLGNRRVRSVGEMVENQFRIGLYRVEKGIRESMSLVHKDKLMPKDIVNSKPITAAIKEFFTSGALSQFMDQDNPLSEVTHKRRISALGPGGLSRDRAGFEVRDVHATHYGRLCPIETPEGPNIGLINSLASYARVNDYGFLEAPYRKVVDGKVTDEIEYLSAIDEDNYVIAQASTKLDENNHFVEDIIQCRSGGEAIFTESSRVQYMDVSAKQMVSAAAALIPFLEHDDANRVLMGANMQRQAVPTLKSEKPLVGTGMEKIVARDSGNCIIARNVGEVAEVDSNRIVIKVDTEKSQTSNLVDIYSLTKFKRSNKNTCINQRPIVNVGDKVEAGDILADGFATDFGELSLGHNLMVAFMPWNGYNFEDSILLSERIVKDDKYTSIHIEEFTCVARDTKLGPEEITADIPNVSESSLAKLDESGIVHIGANVEAGDILVAKITPKAEQQLTPEERLLRAIFNEKASNVVDSSLRMPSGTSGTVINVQVFENDKGGKSKRALKIEKELIDKARKDFDEEFAVIESVVKSSIEQEVVGAKIQKAKGLKKGAILTKEFLATLPLSKWLEISFEDEKLEEKVQNAREYYEEAKIAIDAKFEAKKKSITQSNELSPGVLKTVKVFVAIKKRIQPGDKMAGRHGNKGVVSRVLPVEDMPYMEDGTPVDVCLNPLGIPSRMNIGQILEAHLGLASYGLGKKIEKTLEKTRKAAELRKTLEEVYNSVGDKKVNLEALNDEEILTLCDNLKGGVPIATPVFDGAKEEDIKSLLKIGGFATNGQMKLFDGRTGKPFDRHVTVGYMYMLKLDHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALQAYGAAYTLREMLTVKSDDIAGRSKMYKNIVDGKLTMNVDVPESFNVLRNEVRALGIDMDFDYSSEEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: MNMA_PROM5
Sequence: MLKTLKDKKLENCSSINNKSKKQKHIVVGLSGGVDSSLSAALLMEDGWKVEGLTLWLMKGEGSCCSEGLVDAAGLCEDLGIQHNILDSRVIFEREVIKKTTEGYESGYTPLPCSMCNKNVKFEEMLKFVIKQKEFTYIATGHYARVIKSSCEHINNSENFQFKDFLLLRGADRNKDQSYFLYSLSQEVLSRLILPLGDLKKEETRKEALRLGLRTAKKPESQDLCLVEHYGSMQKFIDNHVKTKNGEIKHINGKTLGTHNGIQHFTIGQRKGLGIAWPEPLYVESLDKQKNIVYVANKNDLLKREAIIKEVNWVSIEAPIKEIEVEAQIRYRSEPVKGILVPLKSKDNLTKRFKLIFEDNQSSVTPGQAAVFYKGEILLGGGLISEFSKK
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YFEK_ECOLI
Sequence: MKKIICLVITLLMTLPVYAKLTAHEEARINAMLEGLAQKKDLIFVRNGDEHTCYEAVSHLRLKLGNTRNRIDTAEQFIDKVASSSSITGKPYIVKIPGKSDENAQPFLHALIAQTDKTVPAEGN
What are the official names of this protein?
Uncharacterized protein YfeK.
Protein: SC6A3_HUMAN
Sequence: MSKSKCSVGLMSSVVAPAKEPNAVGPKEVELILVKEQNGVQLTSSTLTNPRQSPVEAQDRETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELALGQFNREGAAGVWKICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTELPWIHCNNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYFERGVLHLHQSHGIDDLGPPRWQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAIDGIRAYLSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIVTTSINSLTSFSSGFVVFSFLGYMAQKHSVPIGDVAKDGPGLIFIIYPEAIATLPLSSAWAVVFFIMLLTLGIDSAMGGMESVITGLIDEFQLLHRHRELFTLFIVLATFLLSLFCVTNGGIYVFTLLDHFAAGTSILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQRPSLYWRLCWKLVSPCFLLFVVVVSIVTFRPPHYGAYIFPDWANALGWVIATSSMAMVPIYAAYKFCSLPGSFREKLAYAIAPEKDRELVDRGEVRQFTLRHWLKV
What is the function of this protein?
Mediates sodium- and chloride-dependent transport of dopamine (PubMed:1406597, PubMed:8302271, PubMed:10375632, PubMed:11093780, PubMed:15505207, PubMed:19478460).  Also mediates sodium- and chloride-dependent transport of norepinephrine (also known as noradrenaline) (By similarity).  Regulator of light-dependent retinal hyaloid vessel regression, downstream of OPN5 signaling (By similarity).
What are the official names of this protein?
Sodium-dependent dopamine transporter, DA transporter, DAT, Solute carrier family 6 member 3.
What is the protein family that this protein belongs to?
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A3 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell projection, neuron projection. Cell projection, axon. Note=Localizes to neurite tips in neuronal cells (By similarity). Colocalizes with SEPTIN4 at axon terminals, especially at the varicosities (By similarity).
Protein: GACI_DICDI
Sequence: MNIKSLRKKNIQNMDQEEVYNRIKENVAHMDEIQRTMEKQQQTFFQMSLQSKQIAESMKKYSMDAAYFNSRIPITDCLSRASEWQNSISEVFNHLGNLLYDRTTQPLKQTISIQLEMVKEGKKKLKNLSTDTSKSSSANLKKDTEAFERTQKETLQLYNDSELALENSTVQTILSSFESYNDFFQRGVFQMSKIKSDIDNYKKIILETNKVAAKLRNYVPKKTFGIKLEEVFARESNKPLPSFLDEIFRYLEKESINTEGMFRVSAGKSSLEALQQKIESGAPLELSASIIDPHCVSSVLKLFLRSLPEPLVLYNVYSKYLTVAKNNNNNNNNNNNNISNSSSNLNIVGSSGNNNSGGGSGGTIITELRRLISTLPVCNQALLKQILLICSLMNQHRDVTKMDLTNLSVVIGPSILEPIPNLKAEDIQRPETFADFNSLFCLLVEHVLTIFPQVSQTSMDMASLPTTIGKLRSQSDISSQTKPLPSLPTSPQNRSAIITGDSSSPSLNTPPVKSSLNSSDFVIVDNGSNNNNNNNTTNTITNNGIADTATPPPPTTPTAPTTPPPPTTPTSNNIATPIININIPNSSNNNNNNNTKRINNKSNLKVDDYLTPIDMQIYYINISSNLGRIKSYVDDIETVNQGIGLIKLFKKISDDHMAPIKNILNYKFKTEKPPMSNDEDKVLRIKRTLFYTYEITMELISHANNTFESSSIEEPTELSKKLEESFKQLDTILTDELSNIEKQQQQQQQQTNDGGGSGISSNTNTSISGDNSENGDSLNSSTSNQSPLNSSILTQLSNQ
What is the function of this protein?
Rho GTPase-activating protein involved in the signal transduction pathway.
What are the official names of this protein?
Rho GTPase-activating protein gacI, GTPase activating factor for raC protein I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSG_GLUOX
Sequence: MNTQPHHSSPDSPQDGGWFPISIRLSGARVLLVGGGEIAVNKGRLLLDHGARIDVLAEKLHPAVQGWVENGRVRHVGERADEAVLRRLLPGCRLVYAATDSRDTNRQVAALADELNIPVCAVDDPGPSSFITPAQVRRGMVRVAVSTGGAAPVLARRLREQIETLLPEGTGRLATYMQSRRAFVSGRYPNVQDRKRIWEDFLDGPGAEAARSGDESRADARLEVLLDGERKSGEVWLVGAGPGDPDLLTLKALHLMQNADSVLYDNLVSPALLDMVRRDAELVFVGKQRDRHALPQDEINREMVRRAQGGERVLRLKGGDPFIFGRGGEEIEALVEAGVAFRLVPGISAANGCAAYSGIPLTHRDCAQACLFVTGHAKADGVLDLPWDDMADRRQTVVIYMGISTLPQLAAGLLGKGLPADWPVAIVERGTQPRQRVFTGTLSTIAQQAAEAQVKSPALVIVGQVVRHRVVSP
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: KDPC_SALG2
Sequence: MIGLRPAFSTMLFLLLLTGGVYPLLTTALGQWWFPWQANGSLIHKDNVIRGSALIGQSFTAAGYFHGRPSATADTPYNPLASGGSNLAASNPELDAQIQSRVAALRAANPQASSAVPVELATASASGLDNNLTPGAAAWQIPRVAAARQLPVEQVAQLVAEYTHRPLARFLGQPVVNIVELNLALDALQGHRAK
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: DPOL_ADE02
Sequence: MALVQAHRARRLHAEAPDSGDQPPRRRVRQQPPRAAPAPARARRRRAPAPSPGGSRAPPTSGGPPASPLLDASSKDTPAAHRPPRGTVVAPRGCGLLQVIDAATNQPLEIRYHLDLARALTRLCEVNLQELPPDLSPRELQTMDSSHLRDVVIKLRPPRADIWTLGSRGVVVRSTITPLEQPDGQGQAAEVEDHQPNPPGEGLKFPLCFLVRGRQVNLVQDVQPVHRCQYCARFYKSQHECSARRRDFYFHHINSHSSNWWREIQFFPIGSHPRTERLFVTYDVETYTWMGAFGKQLVPFMLVMKFGGDEPLVTAARDLAVDLGWDRWEQDPLTFYCITPEKMAIGRQFRTFRDHLQMLMARDLWSSFVASNPHLADWALSEHGLSSPEELTYEELKKLPSIKGTPRFLELYIVGHNINGFDEIVLAAQVINNRSEVPGPFRITRNFMPRAGKILFNDVTFALPNPRSKKRTDFLLWEQGGCDDTDFKYQYLKVMVRDTFALTHTSLRKAAQAYALPVEKGCCAYQAVNQFYMLGSYRSEADGFPIQEYWKDREEFVLNRELWKKKGQDKYDIIKETLDYCALDVQVTAELVNKLRDSYASFVRDAVGLTDASFNVFQRPTISSNSHAIFRQIVFRAEQPARSNLGPDLLAPSHELYDYVRASIRGGRCYPTYLGILREPLYVYDICGMYASALTHPMPWGPPLNPYERALAARAWQQALDLQGCKIDYFDARLLPGVFTVDADPPDETQLDPLPPFCSRKGGRLCWTNERLRGEVATSVDLVTLHNRGWRVHLVPDERTTVFPEWRCVAREYVQLNIAAKERADRDKNQTLRSIAKLLSNALYGSFATKLDNKKIVFSDQMDAATLKGITAGQVNIKSSSFLETDNLSAEVMPAFEREYSPQQLALADSDAEESEDERAPTPFYSPPSGTPGHVAYTYKPITFLDAEEGDMCLHTLERVDPLVDNDRYPSHLASFVLAWTRAFVSEWSEFLYEEDRGTPLEDRPLKSVYGDTDSLFVTERGHRLMETRGKKRIKKHGGNLVFDPERPELTWLVECETVCGACGADAYSPESVFLAPKLYALKSLHCPSCGASSKGKLRAKGHAAEGLDYDTMVKCYLADAQGEDRQRFSTSRTSLKRTLASAQPGAHPFTVTQTTLTRTLRPWKDMTLARLDEHRLLPYSESRPNPRNEEICWIEMP
What is the function of this protein?
Eukaryotic-type DNA polymerase involved in viral genomic replication.  DNA synthesis is protein primed, and acts in a strand displacement replication.  Assembles in complex with viral pTP, DBP, host NFIA and host POU2F1/OCT1 on viral origin of replication.  The polymerase covalently transfers dCMP onto pTP, thereby initiating complementary strand synthesis.
What are the official names of this protein?
DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: PELE_ASPNG
Sequence: MAFAHHAEAAQSSIVSGSAPGFAAGVTGGGDATPVYPTTIDELKEYLTSSSPQNIVIEGTFDFVGSEGTKTYQACNIYDCTPDNGGQAILNTLGGCGDTSTYDVTIDVAGYQGINVASDKTLVGKGTGAVLNGKGLRFVGVSNIIIQNIEITNLNPKYVWGGDALTFSDTNQIWIDHVTTSSLGRQHYSFGQESDNAITISNSFINGKTDYSATCDGHTYWGLELVGSSDQITFYKNYVYYTSGRSPALSGNTLFHAVNSVWADNSGHAIEGTDNGMGLFEGNVFNNVPTIVQSGFVGQLFSSESANLSQCETSLGRDCVTNAYTSSGSFSYDDDGFFVDFENLPIVSAASASSIASTVPSDAGNTLSST
What is the function of this protein?
Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase.  Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins (By similarity).
What are the official names of this protein?
Probable pectin lyase E, PLE.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: DEF_BUCA5
Sequence: MSLLKILYYPDIRLRILAKPVKEINKKIQKIANDMIDTMYQEEGIGLAATQVNIPLQIIVVNTMEQKKNNLVLINPKIIKKEGDISIEEGCLSIPEYQASIPRSNYIQVQAVNLDGEKIEIEAKSILSICIQHEIDHLKGKLFIDYLSKFKRERIQKKFEKINKKNKKFSIKE
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: CADH1_CHICK
Sequence: MGRRWGSPALQRFPVLVLLLLLQVCGRRCDEAAPCQPGFAAETFSFSVPQDSVAAGRELGRVSFAACSGRPWAVYVPTDTRFKVNGDGVVSTKRPLTLYGRKISFTIYAQDAMGKRHSARVTVGRHRHRRHHHNHHLQDTTPAVLTFPKHDPGFLRRQKRDWVIPPISCLENHRGPYPMRLVQIKSNKDKESKVYYSITGQGADSPPVGIFIIERETGWLEVTEQLDREKIDRYTLLSHAVSASGQPVEDPMEIIITVMDQNDNKPVFIKEVFVGYIEENAKPGTSVMTVNATDADDAVNTDNGIVSYSIVSQQPPRPHPQMFTIDPAKGIISVLGTGLDRETTPNYTLIVQATDQEGKGLSNTATAIIEVTDANDNIPIFNPTMYEGVVEENKPGTEVARLTVTDQDAPGSPAWQAVYHIKSGNLDGAFSIITDPSTNNGILKTAKGLDYETKSRYDLVVTVENKVPLSVPITLSTASVLVTVLDVNEPPVFVPPIKRVGVPEDLPVGQQVTSYTAQDPDRDMRQKITYRMGSDPAGWLYIHPENGIVTATQPLDRESVHAINSTYKAIILAVDNGIPDTTGTGTLLLLLQDVNDNGPTPEPRSFEICSRQPEKQILSIVDKDLPPHTYPFKAALEHGSSNNWTVEIRGQDELAMGLKKELEPGEYNIFVKLTDSQGKAQVTQVKAQVCECEGTAKNCERRSYIVGGLGVPAILGILGGILALLILLLLLLLFARRRKVEKEPLLPPEDDMRDNVYNYDEEGGGEEDQDYDLSQLHRGLDARPEVIRNDVAPPLMAAPQYRPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGGGSEATSLSSLNSSASDQDQDYDYLNEWGNRFKKLAELYGGGEDDE
What is the function of this protein?
Cadherins are calcium-dependent cell adhesion proteins.  They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.  E-cadherin is a ligand for integrin alpha-E/beta-7.
What are the official names of this protein?
Cadherin-1, Epithelial cadherin, E-cadherin, Liver cell adhesion molecule, L-CAM.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: EFUI_HORCR
Sequence: MTAAVQSPTVNTTLNYFREVADGGLSEIRHGTVGSTRMKYNTQPVVVNDIRSNEGEFSLDKQGFQLVTSATKVKAFDEKTVKEQYYEELIDLIKETTGASFVLPMNHLVRQQLWESIHEIPADADDAAIVDTTAAPAMSVHIDQTPEGAELILQMLMQADAGRLGKTRWGIINAWRPLKLIRREPLAVCDVRSVPDSDLRVLGVIYPLPDGMVYNGSSDLKSDTWNVAANPEHKWYYASNMTPDEVLLLKMYDTKLDGRARKCPHSAFKRSYDEGPARESIETRCLVFWEDQERE
What is the function of this protein?
Hydroxylase/desaturase; part of the gene cluster that mediates the biosynthesis of enfumafungin, a glycosylated fernene-type triterpenoid with potent antifungal activity, mediated by its interaction with beta-1,3-glucan synthase and the fungal cell wall (PubMed:30051576).  The pathway begins with the terpene cyclase-glycosyl transferase fusion protein that most likely uses 2,3-oxidosqualene as substrate and catalyzes glycosylation immediately after cyclization (Probable).  The fernene glycoside then could be processed by the desaturase efuI which catalyzes isomerization of a double bond established by efuA to form the core structure (Probable).  The latter would then undergo a series of hydroxylations in unknown order at C-2, C-19, C-23 and C-25, which would be catalyzed by two of the three cytochrome P450 monooxygenases efuB, efuG or efuH (Probable).  The hydroxy-group at C-25 becomes oxidized by the dehydrogenase efuE to enable a spontaneous, non-enzymatic hemiacetal formation with C-23 (Probable).  After hydroxylation at C-2, acetylation by the acetyltransferase efuC takes place (Probable).  The final steps in enfumafungin biosynthesis require expansion of the 5-membered ring by lactonization via a Baeyer-Villiger reaction mediated by one of the BGC's cytochrome P450 monooxygenases (efuB, efuG or efuH) followed by ring cleavage (Probable).  This type of reaction would establish a double bond between C-20 and C-21 which could be reduced by the reductase efuL to form the final product (Probable).
What are the official names of this protein?
Hydroxylase/desaturase efuI, Enfumafungin biosynthesis cluster protein I.
What is the protein family that this protein belongs to?
Belongs to the asaB hydroxylase/desaturase family.
Protein: RL28_LACGA
Sequence: MAKDIITGRKTVFGNKRSKALNSVRRSWKPNLQKVRILVDGKPKRVWVSARALKSGKVKRA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: TUFT1_BOVIN
Sequence: MNGTRNWCTLVDVHPEGQTAGSVDVLRLTLQSELTGDELERIAQKAGRKTYAMVSSHSTSHSLASELVESNDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRDPGDSVHKQEIQVVLEKQNGLSEGPLTTYSSPPEVDTHINEDVESLRKTVQDLLVKLQEAEQQHQSDCSAFKVTLSQYQREAKQSQVALQRAEDRAEQKEAEVGELQRRLQGMETEYQAILAKVREGETALEELRSKNVDCQAEQEKAANLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDTTIQELKEKIAYLEAENLEMHDRMEHLIEKQISHGNFSTQNRAKTENLGSIRISKPPSPKPMPLIRVVET
What is the function of this protein?
Involved in the mineralization and structural organization of enamel.
What are the official names of this protein?
Tuftelin, Enamelin.
What is the protein family that this protein belongs to?
Belongs to the tuftelin family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted at a very early stage of enamel formation, and tightly bound to the surface of the growing crystallites.
Protein: SIF3_SCHPO
Sequence: MSTKDKLNLPPKRTINTRLSTPVHIPPPINSESTRITPQHGSPPRFGDHRISAAQGLFQRRRNARKIDHPLGWFLKNRHAAAHIPQRTTKTSQKLVLLPENHAVNSFNEEESNYEDLLTPSDAYNLIKLENLPRDKREELGFPRATAYCVCEAFQLPKVKHFLKHYHKVRAKKYDEVLYAVYHLPLVYGRSESCRVSSGPAPDDMPSSASNHNQKHLDSDKPDNENFDSHIISQLYRISEIFVFSYGVVVFWNFSLSQEKDILADLTFGGDNSLMVKPLAEEECEIEDLHFHYAPNTKRPRIYNDMIHIPSADNKMKLAMSHALAQSVKLSRFELRTDVTMNSALFYPKKLALYGHLGLSRVEVVRMSGHLFQLRVDVNLISNILDTPDFLWDSEPLLLPLYTAFREYLEIGPRTNVLNRRCKVIFDMLDIFGKSSADRKMNSITWIIIILISLFVIIFTLEVILRLRWAHR
What are the official names of this protein?
Sad1-interacting factor 3.
What is the protein family that this protein belongs to?
Belongs to the RMD1/sif2 family.
What are the subcellular locations of this protein?
Nucleus membrane; Single-pass membrane protein.
Protein: SHO1_SPORE
Sequence: MPGKRGGGGGIDIGLIFAHKILTVLLLLSTVGWIVAFIGQCAAEAGSGGRQGVLWFAIFLQLFLIVAKYLLVMTDSLGTHRLQLTTFTSIALVFSVIGINSGIYSSNSSEEAVAAGWFLITLTNIVWLLFLTTEEESALYPIVNIANDGVTPPAARTSGRYNGGGGAGGQSMRMAGGGAGTGLGGAGYAAGNGSAYSGGFQGGAAGGYQPAFGNSPSAADITTANGTGLGAPKMSSAASVRSRAANDTATGGVGGISQDAPSVASHGAPASPAQPGAKGSELPDYGYKARALYAYQANADDPTEISFSKGEVLDIVDNSGKWWQARKSNGETGIVPSNYMQLL
What is the function of this protein?
Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.
What are the official names of this protein?
High osmolarity signaling protein SHO1, Osmosensor SHO1.
What is the protein family that this protein belongs to?
Belongs to the SHO1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYN_ACTPJ
Sequence: MSKFPTVSEILSGKVAVGEEVAVRGWVRTRRDSKAGLSFLAVYDGSCFDPLQSIINNDLANYNDEVLRLTAGCSVIVTGKVVESPAEGQAVELHATHVEVVGWVEDPDTYPMAAKRHSIEYLREVAHLRPRTNLIGAVARVRHCLAQAIHRFFNEQGFYWVATPLITASDTEGAGEMFRVSTLDLESLPRTDEGKVDFSQDFFGKESFLTVSGQLNGETYACALSKVYTFGPTFRAENSNTTRHLAEFWMVEPEFAFATLADNAKLAEDMLKYVFKAVLEERKDDMQFFAKHIDKDVITRLENFIASPFAQVDYTDAIEILLKSGKEFEFPVSWGIDLSSEHERFLAEEYFKSPVVVKNYPKDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDTRMVEMGLNPEDYWWYRDLRKYGTVPHSGFGLGFERLIVYVTGLQNIREVIPFPRAPRNANF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SWT14_ARATH
Sequence: MVLTHNVLAVTFGVLGNIISFIVFLAPVPTFVRICKKKSIEGFESLPYVSALFSAMLWIYYALQKDGAGFLLITINAVGCFIETIYIILFITYANKKARISTLKVLGLLNFLGFAAIILVCELLTKGSNREKVLGGICVGFSVCVFAAPLSIMRVVIRTKSVEFMPFSLSLFLTISAITWLFYGLAIKDFYVALPNILGAFLGAVQMILYVIFKYYKTPLVVDETEKPKTVSDHSINMVKLSSTPASGDLTVQPQTNPDVSHPIKTHGGDLEDQMDKKMPN
What is the function of this protein?
Mediates both low-affinity uptake and efflux of sugar across the plasma membrane.
What are the official names of this protein?
Bidirectional sugar transporter SWEET14, AtSWEET14, Protein SUGARS WILL EVENTUALLY BE EXPORTED TRANSPORTERS 14.
What is the protein family that this protein belongs to?
Belongs to the SWEET sugar transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: OBG_STRU0
Sequence: MSMFLDTAKISVQAGRGGDGMVAFRREKYVPNGGPWGGDGGKGGSVIFKVDEGLRTLMDFRYNRKFRAKAGEKGMTKGMHGRGSEDLIVLVPQGTTVKDAETGKVITDLVENGQEYVIAKGGRGGRGNIRFATPRNPAPEIAENGEPGEERELELELKILADVGLVGFPSVGKSTLLSVVSAAKPKIGAYHFTTIVPNLGMVRTKSGDSFAMADLPGLIEGASQGIGLGTQFLRHIERTRVILHVIDMSASEGRDPYEDYVSINNELETYNLRLLERPQIIVANKMDMPEAEEHLAAFKEKLAAEYDEFDDMPQIFPVSTLAKQGLDSLLDATANLLASTDEFLLYDESDYQVEDEVYYGFSEEEKAFEITRDDDASWVLSGEKLERLFVMTNMERDESIMKFARQLRGMGVDEALRERGAKDGDLVRIGNFEFEFVD
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_DEIRA
Sequence: MLTFSFLTLFPELLTPFAQEAIVGKARERGLIDVRLVNLRDYAQNKHLKVDDTPYGGGAGMVIRVDVAARALDAACQAGPRPDEVILFTPAGERFTQQVAEELANKQHLVFLCGRYEGFDARVEGLVTRELSLGDFVMMGGEAAAACVLEAVARLRPGVLGDEASHQQDSFSSGLLDYPEYTRPPEWEGHSVPDVLRGGNHAAVARWRRDQALERTLRRRPDLLPGAGLTPQDSAALLALGVTPEQLSIWDAPPPPAPKVRRKKKPSAEDKAPTDTSSE
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_MOOTA
Sequence: MRNYEVVFVIRPDLEAEATTAVVEKFTQLITDQGGQVTRVDQWGKKRMAYEVRKYREGYYVLVEFKGTPAVAQELERVLKISDDVIRYLITRLEEEAS
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: DIVIB_WEIKK
Sequence: MNEKNKNDESKHQEDKLQDQKMWNRINKFFSRSIGQSAKRAPKPKAISKSQSFRILNRFNAMERNSIHMIVILSIISLLLILLLSPLMRFQKVEITGNHDLTKAEVLAASGINKKIPAWQLLSEQHYFIQRAEKNSQIKKVKISYLNMQVAQIKIEENSKVGLVTKKDKNYYILADGKFIPAQSVGEKPQRLPNYEKFPNDKTIKRVAMQFNGISKALQNSVSEVIWSPDHEDDEKVILIMDDGNKVLIKASDIKNKLKYYPGMVAQIDKNGTFNFQVGTYFQQY
What is the function of this protein?
Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.
What are the official names of this protein?
Cell division protein DivIB.
What is the protein family that this protein belongs to?
Belongs to the FtsQ/DivIB family. DivIB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: CA021_MOUSE
Sequence: MGCASAKHVATVQNEEEAQRGKSYQNGDVFGDEYRIKPVEEVKYMKNGAEEEQKIAARNQENLEKSASSNTRLKTNKEIPGLVHQPRANMHISESQQEFFRMLDEKIEKGRDYCSEEEDIT
What are the official names of this protein?
Uncharacterized protein C1orf21 homolog.
Protein: PUR6_YEAST
Sequence: MDSRTVGILGGGQLGRMIVEAANRLNIKTVILDAENSPAKQISNSNDHVNGSFSNPLDIEKLAEKCDVLTIEIEHVDVPTLKNLQVKHPKLKIYPSPETIRLIQDKYIQKEHLIKNGIAVTQSVPVEQASETSLLNVGRDLGFPFVLKSRTLAYDGRGNFVVKNKEMIPEALEVLKDRPLYAEKWAPFTKELAVMIVRSVNGLVFSYPIVETIHKDNICDLCYAPARVPDSVQLKAKLLAENAIKSFPGCGIFGVEMFYLETGELLINEIAPRPHNSGHYTIDACVTSQFEAHLRSILDLPMPKNFTSFSTITTNAIMLNVLGDKHTKDKELETCERALATPGSSVYLYGKESRPNRKVGHINIIASSMAECEQRLNYITGRTDIPIKISVAQKLDLEAMVKPLVGIIMGSDSDLPVMSAACAVLKDFGVPFEVTIVSAHRTPHRMSAYAISASKRGIKTIIAGAGGAAHLPGMVAAMTPLPVIGVPVKGSCLDGVDSLHSIVQMPRGVPVATVAINNSTNAALLAVRLLGAYDSSYTTKMEQFLLKQEEEVLVKAQKLETVGYEAYLENK
What are the official names of this protein?
Phosphoribosylaminoimidazole carboxylase, AIR carboxylase, AIRC.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily.
Protein: STS1_YEAS1
Sequence: MMGFEWGFKPSSKITQSTVSSQGTGNVMIPTAGVKQKRRYANEEQEEEELPRNKNVMKYGGVSKRRPQPGSLIRGQPLPLQRGMELMNKNQLQQLLVDLMTKHPEIQQSVHTRVIGLDFSIQKCLDMLKQKSEAVYQSIPYNRSYESNKLDDYAFVRMKPQILEFLNCLVDFILDNIPPRLENLHASLKFLDICTELVIKLPRFELASNNYYYDKCIEQLSHVWCTLIEHVARDRIILLADNSSVWKSHMTRLQVYNEHSNGLLERPLQLFKSLDMGSPSAASSSTLSLQESIIYHHDTMTANENNNNSGSAATDSPFN
What is the function of this protein?
Involved in ubiquitin-mediated protein degradation.  Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates.  Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins (By similarity).
What are the official names of this protein?
Tethering factor for nuclear proteasome STS1, Dumbbell former protein 8, SEC23 suppressor 1.
What is the protein family that this protein belongs to?
Belongs to the cut8/STS1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.