PharMolix/UniProtQA huggingface dataset:
Protein: PEO1_MOUSE
Sequence: MWLLLRRAYPLRILLPLRGEWVGRRGLPRSLAPGPPRRRYRKEALPALEMPVSPVTTTEIRQYLRAHGIPFQDGHSCLRAPSPFVVSSDIKNEKKDAPTSFCLFIDKTTGHFLCMTSLAEGSWEDLQASVEGRGDGAKEGVLLREGPEAEVREEVLRIWNRAIPLWELPDPEEAQLARVMFGLTKVTDDTLRRFSVRYLRSARSLVFPWFTPGSSGLRGLKLLGAEGQENGVQYVETTIPRPGVYHNLFGLPLISRRDTEVVVTSRELDSLALSQSTGLPTLSLPRGTVCLPPALLPYLEQFRRIVFWLGDDLRSWEAAKLFARKLNPKRCSLVRPGNQQPRPLEALNQGLSLPRILRTALPAWHKSIVSFRQLREEVLGELSNVEQAAGVRWSRFPDLNRLLKGHRKGELTVFTGPTGSGKTTFISEYALDLCTQGVNTLWGSFEISNVRLARVMLTQFAVTRLEEQLDKYEEWADRFEDLPLYFMTFHGQQSIRSVIDTMQHAVYVYDVCHVVIDNLQFMMGHEQLSSDRIAAQDYIVGAFRKFATDNSCHVTLVIHPRKEDDDKELQTASIFGSAKASQEADNVLILQDRKLVTGPGKRYLQVSKNRFDGDVGVFPLEFNKNSLTFSIPPKSKARLKKIKDDNGLVAKKSSSGKKGAAHQNPEICLGQDPSPAQPDTSKSSG
What is the function of this protein?
Mitochondrial helicase involved in mtDNA replication and repair (By similarity).  Might have a role in mtDNA repair (By similarity).  Has DNA strand separation activity needed to form a processive replication fork for leading strand synthesis which is catalyzed by the formation of a replisome complex with POLG and mtSDB (By similarity).  Preferentially unwinds DNA substrates with pre-existing 5'-and 3'- single-stranded tails but is also active on a 5'- flap substrate (By similarity).  Can dissociate the invading strand of immobile or mobile D-loop DNA structures irrespective of the single strand polarity of the third strand (By similarity).  In addition to its DNA strand separation activity, also has DNA strand annealing, DNA strand-exchange and DNA branch migration activities (By similarity).
What are the official names of this protein?
Twinkle mtDNA helicase, Progressive external ophthalmoplegia 1 protein homolog, T7 gp4-like protein with intramitochondrial nucleoid localization, T7-like mitochondrial DNA helicase, Twinkle protein, mitochondrial.
What are the subcellular locations of this protein?
Mitochondrion matrix, mitochondrion nucleoid. Note=Colocalizes with mtDNA in mitochondrial nucleoids, a nucleoproteins complex consisting of a number of copies of proteins associated with mtDNA, probably involved in mtDNA maintenance and expression.
Protein: RECA_NEISU
Sequence: STGSLGVDLALGVGGLPRGRVVEIFGPESSGKTTLCLEAIAQCQKNGGICAFIDAEHAFDPIYARKLGVKVEELYLSQPDTGEQALEICDTLVRSGGIDMVVVDSVAALVPKAEIEGEMGDSHVGLQARLMSQALRKLTGHIKRTNTLVVFINQIRMKIGVMFGSPETTTGGNALKFYASVRLDIRRTGQIKKGDDVIGNETKVKVIKNKVAPPFRQAEFDILYGEGISWEGELIDL
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity).
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOXH1_DANRE
Sequence: MTKHWGGPGLLAPPVITVGEGAQRDHHLDCRIGYSSSKRSCHRSSNPLLELGGRLDKSTGMAQDSCYRAKATNQGPWELQDGNSSGGKKKNYQRYPKPPYSYLAMIAMVIQNSPEKKLTLSEILKEISTLFPFFKGNYKGWRDSVRHNLSSYDCFVKVLKDPGKPQGKGNFWTVEVNRIPLELLKRQNTAVSRQDETIFAQDLAPYIFQGYSQPNKSKPLPPESSLPPVPTRQSPPPSEDPYRPKLDSTFAIDSLLHSLRPASSAGEGLRERESWGVGPPPHTRSTTPPRPCNASYNGSSSASSVSPASDFSDEDWRGVTVVGKRSGDRGITSDAYSDSCPPPNKSSKRGNTPPWELPTSYAKYTPPNAVAPPSMRFNGNPFMPLGGIPFYGYGGAHVTTSHLIGHPYWPILPSGPVSIQAPPLLMDLDSMLQSVPPNKSVFDALGSNNQTVHPSPNQYALQNGPSLCKYSL
What is the function of this protein?
Transcriptional activator.  Activates an activin response element (ARE).  Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3'.  Modulator of nodal signaling required for organizer formation.  Also required for the development of dorsal axial structures and left-right symmetry.
What are the official names of this protein?
Forkhead box protein H1, Forkhead activin signal transducer 1, Fast-1, Schmalspur protein.
Protein: SYGA_SYNPW
Sequence: MHFQDIISTLNRFWSEQGCLLLQPYDTEKGAGTMSPHTVLRAIGPEPWAVAYPEPCRRPTDGRYGDNPNRAQHYFQYQVLIKPSPDGIQETYLASLEALGIKAADHDIRFVEDNWESPTLGAWGVGWEVWLDGMEVTQFTYFQQCGGLDCKPVSIEITYGLERLAMYLQDVESIWDLSWNAQRSYGDIWLPFEKGQCHFNFEASNPERLKQLFAIYEAEATDLIAQNLPAPALDFVLKCSHTFNLLEARGVISVTERTATIGRIRTLARKVAEAWLAEREALGFPLLEPSAATAAV
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_PARUW
Sequence: MAHKKGQGSTRNGRDSHSKRLGIKVGSGEVVRAGSILVRQRGTKWHPAKNVGRGTDDTLFALADGVVAFRKSNKTYISIETGA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: AROE_METAR
Sequence: MMTIYGVVGYPVEHSLSPVMHNAAFKALDMDCAYHKFEVKGEHLKDAILGARYLGFGGLNVTIPHKEAALRIMEPDRTALEIGAANTLDFKQMRAFNTDAAGAIDALRDGGVELENKGVLVLGAGGAARAVVYGLVKEGATVTIANRTTAKAADLAAYMRSFGSVFGTSLDSLGEKVRAVDIVINTTPIGMGWEDKPLVTRDMLDRSQAVFDLVYRPVETPLLREARAAGAKTIDGISMLARQGAKSFEIWTGVKPPVDVMERSARDAL
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: RL22_LIMRJ
Sequence: MAENITSAKATAKMVRVSARKVRLVLDAIRGKSVAEAFAILKFTPRGAASDVEKVLKSAVANAENNFDLDRASLVVSEAFANEGPTLKRFRPRAKGSASPINKRTSHITVVVTER
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RL23_ACIBT
Sequence: MNNERIYQVLKGPVFSEKAQVLGDTAGVQVFKVDINATKLEIKKAVEKLFGVEVVKVNTTITKGKTKRFGRTLGRRSDVKKAYVTLKAGQDVEMADLGDTAESAAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: KTHY_COPPD
Sequence: MFIVVEGIDGCGKSTVASLLAAEIGKKRPVFHTFEPGHVRDGLYRELIMENVDNPFVVAALFTIDRAEHVKKMIKPALAKGEWVVCERYADSTLAYQGYGMGLDKELINRMNEEAIDGLWPDKIFYLDIEPHLALARLQNKEKDALEGQGLEFLQRVREGYEEIARTRGYIYMDATLPPEIIVKRILEEVKLQ
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: RIMK_RHOBA
Sequence: MKLAILSCSPRCYSTRRLVEAAEQRGIKAKVLNTLKFAIDLAEGEPDLYYRSKQLSDYDGVLPRIGASITYFGTAVVRQFEQMDVFCANSSAGISNSRDKLRSLQILSRHQIGIPKTTFVRDRKDILPAIERVGGSPVIIKLLEGTQGVGVILAENVKVAEAIIETLQSTKQNVLVQQFVAESRGKDIRAFVIGDRVVAAMRRVAVGNEFRSNVHRGGQTEAVVLDETYAETAVRAAQIMGLRVAGVDMLEGTNGPQVMEVNSSPGLEGIESATKLDIAGAIIDYMSAQVDFPEVDVRQRLTVSRGYGVTELHVRDGSDYVGKTIDESGLPELDINVLTLYRGTTVIPNPRLKRTLEPHDRLLCFGKLEAMRGMVPEKVRKQRRPKIKRLPDSAATIHAESSRDD
What are the official names of this protein?
Probable alpha-L-glutamate ligase.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: UTP25_ASHGO
Sequence: MGITDSHGIMDGKRGRKQLRNITRIGRAIHVQEDEAKSREEHTVEEAQAGEQTSNRKRGNHPAEDDGGARESQSYGALLTLLSAEHGKQRKKRLRKAEAEAAEAAEAGEDPEEAITAALENSAQDAEDAEDAFDDSGESDEEQDHFDVHFNRVSAADVAQLDAAFKNGRAQYRVQKEARGEEEILYSKPVASSEGTEGPVRVPARSLRGYAIKQRLRMHNGLTADDPEKPLTPQQKVLLDPMFQYQDILYEYEGYDREREYRELYTLHILNHVYKTRDRILKNNQKLQDNPDQELLDQGFTRPKALVVVPTRATAYDVVDLLLQQSGIEQVDKKSKFKDQFYDPSLPPASKPKSFQHVFKGNTNDFFVLGMKFTRKAIRLYSNFYQSDVIVCSPLGLQLIIENTDKKKRQDDFLSSIEVMVLDQLHSIEFQNIAHVSNIFAHINKIPQQQRDADFSRIRMWYIEDQAKLFRQTMVFTRYISPFANALLNRKCANWAGRVKSHRVVSAEKSVIGQLGLKLRQIFQRFEVLGGSTVDEPDFRFKFFTSVVVPGIEKTTGYDSGILLYIPEYTDFIRVRNYLKDKTRILFGDINEYSDQRQLTSNRALFQLGRIKVLLYTERLHHFRRFELKGVKSVILYKPPSNPEFYQELLRYIGKSAFLGVADLNIATVRCLYSKMDSLALERIVGTKRAAVLTHGQNEVYEFK
What is the function of this protein?
DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 25, U3 snoRNA-associated protein 25, U three protein 25.
What is the protein family that this protein belongs to?
Belongs to the UTP25 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: SR1A_PHYPO
Sequence: MKSTFLFALFVLFLAASEAATDYPTNPPTTPPTPAPTSTPLPSSAASPELVAQLLNAPSELDRIKLLKDNQFVFDFKNSKLGVTQGTGGKTVATSRTNFPAVIGHNVAMTVGFIEACGINLPHTHPRATEINFIASGKFEAGFFLENQAKFIGHTLEAGMATVFPQGAIHFEINMNCEPAMFVAAFNNEDPGVQTTASSFFGLPADVVGVSLNISSIQTVEDLGKHLPQNPAVAMQACMKRCGFSD
What are the official names of this protein?
Spherulin-1A.
What is the protein family that this protein belongs to?
Belongs to the germin family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: DYLT3_HUMAN
Sequence: MEEYHRHCDEVGFNAEEAHNIVKECVDGVLGGEDYNHNNINQWTASIVEQSLTHLVKLGKAYKYIVTCAVVQKSAYGFHTASSCFWDTTSDGTCTVRWENRTMNCIVNVFAIAIVL
What is the function of this protein?
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function.  Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.  Probably binds BUB3 as part of transport cargo.  Required for the efficient progression through mitosis (By similarity).
What are the official names of this protein?
Dynein light chain Tctex-type 3, Protein 91/23, T-complex-associated testis-expressed 1-like.
What is the protein family that this protein belongs to?
Belongs to the dynein light chain Tctex-type family.
Protein: RS19_PARL1
Sequence: MSRSLKKGPFVDGYLLKKAETTRSSGRKEVIKMWSRRSTILPQFVGLTFGVHNGKKHVPVLVTEDMVGHKFGEFSPTRTYFGHTSDKKAKKG
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: GPDA_SHEON
Sequence: MNNSADITVLGAGSYGTALAISLASNGHKTLLWGHDPAHMQTLAEDKCNQAFLPGIAFPECLHIEADLAKALAASNNVLVVVPSHVFGTVLAQAKPLLRQDARIVWATKGLEPETGRLLQDVARDVLGEQYPLAVLSGPTFAKELAMGLPTAISVAGTCPQFTAELVELLHSPKRLRVYANDDFIGLQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLVELTRLGEALGASTATFMGMAGLGDLVLTCTDNQSRNRRFGLALGKGCDVDTAQVEIGQVVEGYRNTKEVFTLAKRLGVEMPITEQIYQVLYQGKSPVDAAKELLGREKKSETPTQ
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYN_OENOB
Sequence: MGETKVIRIEDVSKFVGQTVKIGVWLRQKRGSGKIAFLQLRDGTGFMQGVVSVGDVDEATFKLAEHLKQESSFYVTGEIHQDSRSEFGFEMAVSDIEIVGESEDYPITPKEHGTDFLFDERHLYLRHQKPFATMKIRDEIIRAIYDFFHKDGFLKLDSPIITDSAPEGTTELFPVKYFDKDAYLSQTGQLYAEAGAMAFGKVYDFGPTFRAEKSSTRRHLTEFWMIDAEMAWMHQEDSLKVQERFIAYLIERVVDNCQVELKMLGRDVEKLRAYTKLPYPRISYDDAVKLLQDNDFKIEWGVDFGSPEETFLAKRFNSPFFIVNFPKAIKAFYMKRPPSRDDVVISADMLAPEGYGEIIGGSERDTDYDYLKQQIISQHLDLSEYSWYLDLRKYGTVPHSGFGLGLERLIRFIAGEDHIRETIPFPRTLNRLHP
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_RHIEC
Sequence: MTDETTKNGPDATAADAAADAAANVEIDNSVQEEAKQPDPLELLKAENAELRDRYLRLAAEMDNLRRRTEREVKDAKSYSVAGFARDMLAVSDNLRRALDAISPEAKATADAGLTTLIEGVEMTERSMLSALERHGVRKLEPVGQKFDPNFHQAMFEVPNSEVPNNTVVQVVQAGFTIGERVLRPAMVGVAKGGPKPVEAEINSVFDEKDA
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_PROMP
Sequence: MSRYRGPRLRVTRRLGELPGLTRKASKKSNPPGQHGQARRKRSEYAIRLEEKQKLRFNYGVSERQLVRYVKKARAQEGSTGTNLLRLLENRLDNVCFRLGFGGTIPGSRQLVNHGHVTINGKVLDIAGYQCKPGDVISIKENKASKKLVEGNIEFPGLANVPPHIELDKPKLTGKINGKCDREWVALEINELLVVEYYSRKV
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: ARNT_ECODH
Sequence: MKSVRYLIGLFAFIACYYLLPISTRLLWQPDETRYAEISREMLASGDWIVPHLLGLRYFEKPIAGYWINSIGQWLFGANNFGVRAGVIFATLLTAALVTWFTLRLWRDKRLALLATVIYLSLFIVYAIGTYAVLDPFIAFWLVAGMCSFWLAMQAQTWKGKSAGFLLLGITCGMGVMTKGFLALAVPVLSVLPWVATQKRWKDLFIYGWLAVISCVLTVLPWGLAIAQREPNFWHYFFWVEHIQRFALDDAQHRAPFWYYVPVIIAGSLPWLGLLPGALYTGWKNRKHSATVYLLSWTIMPLLFFSVAKGKLPTYILSCFASLAMLMAHYALLAAKNNPLALRINGWINIAFGVTGIIATFVVSPWGPMNTPVWQTFESYKVFCAWSIFSLWAFFGWYTLTNVEKTWPFAALCPLGLALLVGFSIPDRVMEGKHPQFFVEMTQESLQPSRYILTDSVGVAAGLAWSLQRDDIIMYRQTGELKYGLNYPDAKGRFVSGDEFANWLNQHRQEGIITLVLSVDRDEDINSLAIPPADAIDRQERLVLIQYRPK
What is the function of this protein?
Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase, 4-amino-4-deoxy-L-arabinose lipid A transferase, Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase, Undecaprenyl phosphate-alpha-L-Ara4N transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 83 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: 3MGH_BACAA
Sequence: MQAPPSFYEGDTLEVAKKLLGQKLVHIVNGIKRSGIIVEVEAYKGPDDKAAHSYGGRRTDRTEVMFGAPGHAYVYLIYGMYHCFNVITAPVGTPQGVLIRALEPVDGIEEIKLARYNKTDITKAQYKNLTNGPGKLCRALGITLEERGVSLQSDTLHIELVPEEKHISSQYKITAGPRINIDYAEEAVHYPWRFYYEGHPFVSKK
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: OXR1_CRYNB
Sequence: MPHHHSLPTSSADFGDFNSAPASSIQTSSLSQDDLLGSYDETIRHSPSVKSHPSPDPRASNLDLLFLDHNAEEHRRPEPTYSPRSRPTGVLPESVPHARSPRRLSTFSSSTSPTSPPSITDAGCDIIFHPFYDHMDVNATRAMQKMQGHGERGASKRSDKMQLRGQASHSRIAPSSSPPHSRLLDTLATTTKLASKWRSVIAHPTSPNTADQTHNGQPKPQIRHAETSPMDITHDTPFASAEQIAGSYIPPTGAPGFTQASVLGMKHHGDGPFEPLTLIGRKDSTSNVLTPEDAIGLKACLPPRQRLTNQWTLLFSLDQHGASLSTLYRLIDIYSVSHQSSGNILVIRDGHGNRFGTYMNEPIVKREGTYYGSGESFLFKLTHSCQTIPYRWTGKNKYFALCEAGFMSFGGGAGAYGLILDSTFTHNSSATCPAYNNDILCELEPLKSQHAQSFQCLGLEVWSTL
What is the function of this protein?
May be involved in protection from oxidative damage.
What are the official names of this protein?
Oxidation resistance protein 1.
What is the protein family that this protein belongs to?
Belongs to the OXR1 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: Y2102_LEIXX
Sequence: MTKTTRLLRATTVAAILLGLTGCAVHLPASAQTPGKQADGVQVSKAWVKAAGSGMTAAFGDVKNTGSGTAIVVGATSSAASSLQLHETVTKNGAETMQEAKSGFRIPAGSTLHLAPGGSHIMLMGLKAPLEAGQKISVTLRFSDGSTSPVAVPVKDFSGANENYKG
What are the official names of this protein?
Putative lipoprotein Lxx21020.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: ANMK_HAHCH
Sequence: MKDREIFAGLMSGTSLDGVDTALASFQGELPETIATSFTPFPSDLKYKLHHLAVADSWRPDELFAAESQLTLLYAEAINDLLQSADIDRSRIHAIGCHGQTIRHRPAINWPYTCQLGNPSLLAEKTGITVIADFRRRDIAAGGEGAPLAPAFHMHVLQHRFPNCAVVNIGGIANITQWSEKANAVVGFDCGPGNILMDAWCSQAFQQNCDHGGQIARTGSINHALLQEMKKEPFFSLSAPKSTGRELFNHDWLQANLQKTASVDDRDILATLTELTAQTICEALNTNTLTHLFVCGGGAHNLFLMERLSRHLPGILVKGTDSAGIDPDFMEAMAFAWLAMRTLARLPGNIPAVTRAQGERILGAIYPA
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: TUSA_ECOLC
Sequence: MTDLFSSPDHTLDALGLRCPEPVMMVRKTVRNMQPGETLLIIADDPATTRDIPGFCTFMEHELVAKETDGLPYRYLIRKGG
What is the function of this protein?
Sulfur carrier protein involved in sulfur trafficking in the cell.  Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA.  Interacts with IscS and stimulates its cysteine desulfurase activity.  Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation.  Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.
What are the official names of this protein?
Sulfur carrier protein TusA, Sulfur mediator TusA, Sulfur transfer protein TusA, tRNA 2-thiouridine synthesizing protein A.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_LEVBA
Sequence: MAHKRGKKYQDAAKQVEADKVYGMGDAIDLVKKIDFAKFDATVEVAFKLNVDTKQADQQLRGALVLPNGTGKETTVIVFAKGDQAKAAEAAGADVVGEQDLVERIQDGWLDFDVAIATPDMMAQVGRLGRVLGPKGLMPNPKTGTVTMNVEKAVSDAKNGQVTYRTDRDGNVAVPFGKVSFDADKLAGNLKSIAETIVRIRPAAVRGTYVQHVSISSTFGPSVDVDLASLLA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: METN1_PSESM
Sequence: MTATAQRQLPLDTTGAGQLAQQAELHPELNRAHVRFINLGKTYHGKQGAVEALGSIDLAIQRGEIFGIIGRSGAGKSSLIRTINRLEQPSSGRVLIDQVDIGEFNEDKLVELRRRIGMIFQHFNLMSAKTVWQNVELPLKVAGVPKEQRARKVTQLLELVGLQDKHKAYPAQLSGGQKQRVGIARALVHDPAILLCDEATSALDPETTQSILGLLREINQRLGLTIVLITHEMAVIRDICHRVVVLEQGRIVEQGPVWQVFGDPQHEVSKTLLAPLQLGLPKEWAERLSEYPQRPDAAILLDVHFTGVSDEGPDLAALFATLGGKVQLLQGGVERIQDRAIGHLILLIAGSPHPREELLLRARQLAPRVEVLGYVG
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CTU2_YEAS6
Sequence: MECQRCPASARNPATVESRKEKFCDECFIKFVSTKQRKQMMKDEYFRNLFKVIYPFEKEGSVSKILLPLSLSDSGSLVMLDIVHDLLLEQTKQHNNRTGFTVDVLTVFTEENVSVIKERMESLINEKMSQLNKISNIFNVHFIDVNEFFNNASEVSTFIIDNENFEIFSKSKSVDDSNILTLKEILGKYCLNNSSRSDLISIIKTQLIKHFAYENGYNAIMWGHSMTKLSEVIISLVVKGKGSQIATFLDSESFDTLNNKPCKYKNLYPMKDLLSVEIESFLQIRNLAQFLINVEETNVKPNCLIARKSLPSLGQQKLVKNMTINEITNKYFQDIQNDYSNIISTVSRTADKLTQPKSSMAKPSQCQICQSKIYTNPSNWLNRITVTSPYPVETTEEKYLFKQWQDSKLGQSHTHYVELLNEIKQGASNSLDVEDGDVKLCYGCLILLNTSIKDKNLVWPKVDTMDITANATNNNKELSQILDQFEINSDGEE
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.  Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation.  May also be involved in protein urmylation.
What are the official names of this protein?
Cytoplasmic tRNA 2-thiolation protein 2, Needs CLA4 to survive protein 2, Thiolation of uridine in cytoplasmic tRNA protein 2.
What is the protein family that this protein belongs to?
Belongs to the CTU2/NCS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18A_SCHPO
Sequence: MSLVVPDNFQHILRLLNTNVDGKVKVMFAMTQIKGVGRRYANIVCKKADIDMSKRAGELTTEELERIVTIIQNPSQFKIPSWFLNRQKDINDGKSFQLLANNVDSKLREDLERLKKIQTHRGLRHALDLRVRGQHTKTTGRRGKTVGVSKKK
What is the function of this protein?
Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA.
What are the official names of this protein?
40S ribosomal protein S18-A.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_BABBA
Sequence: MTNIRKSHPLMKIINNTFIDLPTPSNISSWWNFGSLLGICLILQILTGLFLAMHYTPDTMTAFSSVTHICRDVNYGWIIRYLHANGASMFFICLFIHVGRGLYYGSYMFLETWNIGVILLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFIITALATVHLLFLHETGSNNPTGISSDMDKIPFHPYYTIKDILGALLMIMALLILVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVASILILILMPMLHTSKQRSMMFRPLSQCLFWVLVADLVTLTWIGGQPVEHPFIIIGQLASILYFSIILVLMPITSIIENSLLKL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.