PharMolix/UniProtQA huggingface dataset:
Protein: FTRV_SPIOL
Sequence: MTTGVAVMSSATAASTATATAAATARIPLFLSRNNSSATVCSTLRCRTITRTRTRARLAICCEVALKSDSSTGFDSSSSSPPEEDEELKKNLEKVGCKVKVKSPLKVYHVPKLPEVELTPDMVGVIKQYVGFWKGKYISPNYPFKVEYRIDVPDRGSVKLVVHLKEEEFEIIAE
What is the function of this protein?
Variable subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin.
What are the official names of this protein?
Ferredoxin-thioredoxin reductase, variable chain, chloroplastic, FTR-V, Ferredoxin-thioredoxin reductase subunit A, FTR-A.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin thioredoxin reductase alpha subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FLIE_TRIL1
Sequence: MEINGISGVGMSTAFPLEKNTSSTSVADGAGKFFKELVGKVNDLSQQSDQAIQKLATGENRNLHETMIAVEKASVSFLFMSQVRNKALEAYQEVMRMPV
What are the official names of this protein?
Flagellar hook-basal body complex protein FliE.
What is the protein family that this protein belongs to?
Belongs to the FliE family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: RBFA_RALSO
Sequence: MPKKSGSASGRNLRIADQIQRDLAELIQREIKNPAMGLVTLQSVSLTPDYAHAKIYFTVLGAEPDAAAAILNEKAGYLHSLLFKRLHIHTVPTLHFHYDGSVERGIEMSRLIDQANASRAKDD
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PY2CR_BACHK
Sequence: MLVISANEQRNLVNMNEVIAYAALALKEFSAERTITPIRGSLPFANEKNTALIMPSVAEGLEALGLKVVTVVPENKKIGKKTINGIVMLSDFQTGEPLALLEGSYLTMIRTGALSGVATKHLARHNAKTLCIIGTGEQAKGIAEAVFAVRDIEKVILYNRTEEKAYAFSQYIQEKFGKPAYVHTNANEAISEADIIVTTTNASTPVFSEKLQKGVHVNAVGSFKPSMQELPSHAIVGANKVVVESKEAALDETGDLQVPIKEGLFKANAIHAELGQIISGEKAGRENDEEITVFKSVGLAVVDIIVAKYLYEKAVESGVGNKIEF
What is the function of this protein?
Catalyzes the reduction of Delta(1)-pyrroline-2-carboxylate (Pyr2C) to L-proline, using preferentially NADPH over NADH as the electron donor.  Is likely involved in a degradation pathway that converts trans-3-hydroxy-L-proline (t3LHyp) to L-proline.
What are the official names of this protein?
Delta(1)-pyrroline-2-carboxylate reductase, Pyr2C reductase, Proline ketimine reductase.
What is the protein family that this protein belongs to?
Belongs to the ornithine cyclodeaminase/mu-crystallin family.
Protein: RPAP2_BOVIN
Sequence: MADWVGPCSAGRKARRSRASRDVAGTKQTSALNQEDASQRKAELEAAVRKKIEFERKALHIVEQLLEENISEEFLRECGKFITPAHYSDVVDERSIIKLCGYPLCQNKLGIVPKQKYKISTKTNKVYDITERKCFCSNFCYKASKFFEAQIPKSPVWIREEERHPDFQLLQDGQSGPSGEEIQLCSKAIKTSDIDSPGHFEKHYESSSSSSHSDSSSDNEQDFVSSILPGNRPNATRPQLHEKSIMKKKAGQKVNSQHESKEQTVVDVIEQLGNCRLDNQEKATACELPLQNVNTQISSNSSLQKKLEASEISDIKYSSSKVTLVGISKKSAEHFKRKFAKSNQVSGSASSSLQVCPEIAKANLLKALKETLIEWKTEETLRFLYGQNYASVCLKSSSTPLVKEEELDEDDMNSDPDSHSPALQELNSLDESLPFRASDTAIKPLPSYENLKKETETLNLRIREFYRGRYVLNEETTKSQDSEEHDPTFPLIDSSSQNQIRKRIVLEKLNKVLPGLLGPLQITLGDIYTQLKNLVHTFRLTNRNIIHKPAEWTLIALVLLSILTSTLGIQKLSQENVMFTQFMTTLLEELHLKNEDLESLTIIFRTSC
What is the function of this protein?
Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes.  Recognizes and binds phosphorylated 'Ser-7' of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of 'Ser-5' of the CTD, thereby promoting transcription of snRNA genes (By similarity).  Downstream of EIF2AK3/PERK, dephosphorylates ERN1, a sensor for the endoplasmic reticulum unfolded protein response (UPR), to abort failed ER-stress adaptation and trigger apoptosis (By similarity).
What are the official names of this protein?
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2, RNA polymerase II-associated protein 2.
What is the protein family that this protein belongs to?
Belongs to the RPAP2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the cytoplasm and the nucleus in a CRM1-dependent manner.
Protein: KA111_PARVI
Sequence: DEEPKESCSDEMCVIYCKGEEYSTGVCDGPQKCKCSD
What is the function of this protein?
Binds and inhibits voltage-sensitive potassium channels.  Inhibits the vertebrate potassium channels Kv1. 1/KCNA1, Kv1. 2/KCNA2 and Kv1. 3/KCNA3 with low affinity.  Also weakly inhibits Kv7. 1/KCNQ1 (10 uM of the toxin inhibits currents by 21. 43%) (PubMed:22511981).
What are the official names of this protein?
Potassium channel toxin alpha-KTx 11.1, Parabutoxin-1, PBTx1.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 11 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RSBW_STAA8
Sequence: MQSKEDFIEMRVPASAEYVSLIRLTLSGVFSRAGATYDDIEDAKIAVSEAVTNAVKHAYKENNNVGIINIYFEILEDKIKIVISDKGDSFDYETTKSKIGPYDKDENIDFLREGGLGLFLIESLMDEVTVYKESGVTISMTKYIKKEQVRNNGERVEIS
What is the function of this protein?
Negative regulator of sigma-B activity.  Phosphorylates and inactivates its specific antagonist protein, RsbV.  Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B) (By similarity).
What are the official names of this protein?
Serine-protein kinase RsbW, Anti-sigma-B factor, Sigma-B negative effector RsbW.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-factor family.
Protein: RS19_CUPNH
Sequence: MTRSAKKGPFCDAHLLKKVEVASSGKDKKPIKTWSRRSTILPEFIGLTIAVHNGRQHVPVYVTENMVGHKLGEFAITRTFKGHAADKKAKR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: RL22_SINMW
Sequence: MGKAKAERRLKDNEAQAVARTIRVSPQKLNLVAALIRGKKVDRALAELEFSRKRIAGTVRKTLESAIANAENNHDLDVDSLIVAEAFVGKSIVMKRFHARGRGRASRVEKPFAHLTIVVREVEAKGEAA
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RL18_BRUO2
Sequence: MASPKETLQRRAARVRRQVKAVANGRPRLSVHRSSKNIYAQIIDDVRGVTLAAASTLDGDLKGKLKTGADSAAAAAVGKLVAERAVKAGVKDVVFDRGAFIYHGRVKALAEAAREGGLSF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RAI2_HUMAN
Sequence: MDDLQSQNLSMDMTDSPPALANNRLENGMAQLITTEAWNINSTDLVKKALVTVPAPSILNPPAESQSGMALKVAATVLQPLCLGESPVVMPIHMQVEGSSAPELNPNGNATYVMTTQGPVQLPVVLEQHVFQHLNSPLVLPQEAPCSSSTIHNNLFQGAEDPEAQPQLLDLRIPSQPQEPTLPFEAVLQNLFPSQGTLGPPPCQPPPGYAPVPPQPFSSPLSPLVPPATLLVPYPVIVPLPVPVPIPIPIPMPQSSESKFSSSFPKPPSSFGLHPFKGTQTPLEKDELKPFDILQPKEYFQLSRHTVIKMGSENEALDLSMKSVPWLKAGEVSPPIFQEDAALDLSVAAHRKSEPPPETLYDSGASVDSSGHTVMEKLPSGMEISFAPATSHEAPAMMDSHISSSDAATEMLSQPNHPSGEVKAENNIEMVGESQAAKVIVSVEDAVPTIFCGKIKGLSGVSTKNFSFKREDSVLQGYDINSQGEESMGNAEPLRKPIKNRSIKLKKVNSQEIHMLPIKKQRLATFFPRK
What are the official names of this protein?
Retinoic acid-induced protein 2.
Protein: RL3_BART1
Sequence: MRSGVIAQKLGMTRIYNDAGEHVPVTVLRLENCQVVAQRTVEKNGYTAVQLGVGFAKVKNTSQALRGHFAKASVEPKAKIAEFRVSPDNLLDIGTEITVEHFVPGQRVDVTGTSIGKGFAGVMKRHNFGGHRASHGNSITHRAHGSTGQCQDPGKVFKGKKMAGHMGQVRVTTQNIEVVSTDIERGLILVRGAVSGSKGSWILVRDAVKKPLPDNAPKPAGIRRLVKEKTEMVAPVTETSEVEGA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: LUTB_OCEIH
Sequence: MSVKIGEISYKERIDKGIDNDFMRQAVSSAQGRFRKGRLSQAEELGNWEDWRQLGSEIRTHTLENIDYYLHQLSEQVEKRGGNVFFAQTAEEANEYIENVVKKKQAKKVVKTKSMVTEEIGLNEALEKSGAEVVESDLGEWILQLDEDPPSHIVTPALHKNRQQIRETFADKRGYDKTDSPEELAAFAREQLRQDFLTADVGITGCNFAIAESGAITLVTNEGNAEMVTSLPDTQITVMGMERLVPTWEDMEVLVSLLTRAAVGQKLTSYITAYTGARLEEEIDGPDDYHLVIVDNGRSKILGTEFQSALHCIRCAACINVCPVYRHVGGHAYNSIYPGPIGAVLTPLLDGYDDHKELPYASSLCAACTEACPVKIPLHEQLIRHREIIVEKEKKSPVSEKIMMKGFAQWASNPAAYKLSTKVARTALKPWTKDEFVENGPGPLKGWTDVRDFPAPGKQSFRAWWSERAKGEKQNGNS
What is the function of this protein?
Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source.  Has probably a role as an electron transporter during oxidation of L-lactate.
What are the official names of this protein?
Lactate utilization protein B.
What is the protein family that this protein belongs to?
Belongs to the LutB/YkgF family.
Protein: OPSD_TETNG
Sequence: MNGTEGPFFYVPMLNTTGIVRSPYDYPQYYLVNPAAYAALGAYMFLLILLGFPINFLTLYVTIEHKKLRTPLNYILLNLAVANLFMVFGGFTTTMYTSMHGYFVLGRLGCNLEGFFATLGGEIGLWSLVVLAIERWMVVCKPISNFRFGENHAIMGLAFTWIMACACAVPPLVGWSRYIPEGMQCSCGVDYYTRAEGFNNESFVVYMFICHFLIPMAVVFFCYGRLLCAVKEAAAAQQESETTQRAEREVTRMVVIMVVAFLICWLPYAGVAWWIFTHQGSEFGPVFMTIPAFFAKSSSIYNPLIYICMNKQFRHCMITTLCCGKNPFEEEEGASTTSKTEASSVSSSSVSPA
What is the function of this protein?
Photoreceptor required for image-forming vision at low light intensity.  While most salt water fish species use retinal as chromophore, most freshwater fish use 3-dehydroretinal, or a mixture of retinal and 3-dehydroretinal (By similarity).  Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins.  Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity).
What are the official names of this protein?
Rhodopsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell projection, cilium, photoreceptor outer segment. Note=Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to disk membranes in the rod outer segment (OS) photosensory cilia.
Protein: LST8_DANRE
Sequence: MNVNQGTVGSDPVILATAGYDHTVRFWQAHSGICTRTVQHQDSQVNSLEVTPDRSMIAAAGYQHIRMYDLNSNNPNPVINYDGVSKNITSVGFHEDGRWMYTGGEDCMARIWDLRSRNLQCQRIFQVNAPINCVCLHPNQAELIVGDQSGVIHIWDLKTDHNEQLIPEPDVSVNSVHIDPDASYMAAVNSSGNCYVWNLAGGMGDEVTQLIPKTKIPAHKRYSLRCKFSPDSTLLATCSADQTCKIWRTSNFSLMTELSIKSNNPGETSRGWMWDCAFSGDSQYIVTASSDNLARLWCVETGEIKREYSGHQKAVVCLAFNDSVLG
What are the official names of this protein?
Target of rapamycin complex subunit lst8, TORC subunit lst8, G protein beta subunit-like, Gable, Protein GbetaL, MTOR associated protein, LST8 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LST8 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREG_METFK
Sequence: MQIKEPLRVGIGGPVGSGKTALTLALCQRLRNVYNIAVVTNDIYTREDAEFLTRNEALAPERIIGVETGGCPHTAIREDASMNLEAVAQLSERFNPLDIVFVESGGDNLAATFSPELSDLTIYVIDVAAGEKIPRKGGPGITKSDLLVINKIDLAPMVGASLEVMEKDARRMRGERPFIFTNLKRGQGLEDIVGFIEKQGLML
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SC231_CANGA
Sequence: MDFDTNEDLNGVRFAWNVFPSSKTDAMQNVVPLGCMYTPLKEIEGLNVVDYNPVVCAGPHCKAILNPYCMIDPRSNSWTCSICKSRNHLPTQYHNLSQENIPIELQQTTVEYLTTKPVQVPPIFLFVVDITTEPDNLQALKESITASLSLLPANALIGLITYGKVVQLHDFSNDTIARCNVFKGDKDYQLEPLVEMLTGQKMTGSIPNTQVTPFSLNRFFLPLEQIEFRFIQVLESLSQDEWSVKPGERPLRATGSALNIASLLLQGCYKNNAARIIVFSSGPDTINPGLIVDLELKNPIRSHHDIDSGNAVHYKKAMKYYNTLADRISENGHTVDLFSGCYDQIGMSEMRKLTDRTGGVLLLTDSFSTAIFKQSYLRLFAKDEDDYMKMSFSAKFQVKSSKELKVQGLIGHASAVKKTSATNISDTTIGIGGTSTWTMGSLLPQHTYAVFFDIASNGPTPVTGDNQQLAYIQFITNYQHSSGTIRTRVTTVANQLQSFGSPLIAASFDQEAAAVLISRIAVHKAETEEGPDVIKWIDRTLIKLCQKYADYNKNDPSSFRLAGNFSLFPQFMYYLRRSQFLSVFNNSPDETAFYRHIFTREDTTNSLIMIQPTLTSFSMESEPEPVLLDSLSVKADTILLLDTFFYILIYHGETIAQWRKAGYQDDPQYADFKELLEEPKLEAAELLVDRFPLPRFIDTEAGGSQARFLLSKLNPSDSYQNMNSAGATIVLTDDISLQNFMLHLQQSVVNTQK
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
What are the official names of this protein?
Protein transport protein SEC23-1.
What is the protein family that this protein belongs to?
Belongs to the SEC23/SEC24 family. SEC23 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SURE_HAHCH
Sequence: MKLLLSNDDGVHAPGLSALADELKNIAEIRVIAPDRDHSGASNSLTLTRPLILQKTSQGFFAVDGTPTDCVHMGLSEMFGYDAERVVSGINSHANLGDDVLYSGTVAAAMEGRFLAQPAIAVSLVNRGQENYATAAKVVANLLLRQLKSPIAPRTVLNVNVPDVPLEDIRGIQLTRLGHRLKGGEPHEIVDPRGRKRYWIAAAGEGDDAGPGTDFYPVEHNYVSITPIHVDMTRYDAFNQLQDWLGETE
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS21_STAAM
Sequence: MSKTVVRKNESLEDALRRFKRSVSKSGTIQEVRKREFYEKPSVKRKKKSEAARKRKFK
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: JUNB_CYPCA
Sequence: MSTKMEQPFYHDDSFLVGYGHNDAALHDYKLQKQSMNLNLTEPYRNLKSDLYHTSGADSGSLKLASPELERLIIQTSNGVLTTPTPGQYLYSRGITDEQEGFAEGFVKALDDLHKMFQMPPPNVSIGAGGVTTCSTTASVFGSSLQSEPPIYTLNAYCPAPSHPSTTISYLPPHVQQSQHPENTHGFQHSGVLPQRYVPLKEEPQTVPDMHSSDCSPPTSPIDMENQERIKAERKRLRNRLAATKCRKRKLERISRLEEKVKVLKNDNAGLSNTASVLRDQVAQLKQKVLRHMNSGCQLMLTSKMEAF
What is the function of this protein?
Transcription factor involved in regulating gene activity following the primary growth factor response.  Binds to the DNA sequence 5'-TGA[CG]TCA-3' (By similarity).
What are the official names of this protein?
Transcription factor JunB, Transcription factor AP-1 subunit JunB.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. Jun subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYOE_FRATH
Sequence: MYFKRYLQLAKPGIIFGNLITLTGGFLLATHREIGFEYLPLFVYVMIGVALMIAAGCVFNNIYDQDIDSSMTRTQNRPLVTGDISVIQATIYGTILLILSCLVLYYLVNLLTLWIIIIGFIVYVGIYTVSKRLTIHATVLGGISGAIPPVAGYTAVVNILDYNALALFLILFFWQIPHSYAIAMLYIDDYKKVKLPMLPIVKGIAYTKKIMLFYLALFVVSCALPAVLGSADLFSFIVCMLVALFWMYKSIQSYRTDTDRVFAKTVFKFSIIVITAICLTMG
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TPC11_MOUSE
Sequence: MSPTQWDFPVELCCRPMAFVTLTGLDVVYNAVHRAVWDAFCANRRADRVPISFKVLPGDHEYPKCRSKRTSYEWYIPKGVLKTGWMNKHLNLVPALVVVFYELDWDEPQWKEKQSECATRVEIVRQSLQGRNTKVAVVLIQKKTPLPPGEDVIASERAAALCNVCELSGKSLFVLPHTDHLVGYIIRLENAFYEHAQTYYYTEIRRVKSHKEFLNKTTHQLLFVRHQFKIAFFSELKQDTQNALKNYRIAYNLVHELRAHETNILEIKTMAGFINYKICRLCFQHNTPLDAIAQFRKHIDLCKKKIGSAELAFEHAAWMAKQFQAFGDLFDEAIKLGLTAIQTQNPGFYYQQAAYYAQERKQHAKALCNHDAAVMYPNPDPLETQSGVLDFYGQRPWRQGILSFDLSDPEKEKAGILAIQLKERSVVHSEIIIALLSNAVAQFKKYKCPRMKSHLMVQMGEEYYYAKDYTKALKLLDYVMCDYRSEAWWTLLTSILTTALKCSYLMAQLKDYITYSLELLGRASTLKDEQKSRIEKNLMNVLMNESPDPEPDCDVLAVKTAQKLWADRVSLAGSNVFQIGVQDFVPFVQCKAKFHAPSFHVDVPVEFDVFLKADCPHPIRFSKLCVSFNNQVYNQFCVLEEASKASEVLENLTQGKMCLVPGKTRKLSFKFVAKTEDVGKKIEITSVDLFLGSESGRCVVLSWQGGGGDAASSQEALQAARSFKRRPKLAEDEIHWDSVIIQASTMIISRVPNISVHLRHEPPALMNEMYCLVVTVQSHEKSPIRDVKLTAGLKPGQDANLTQKTHVTLHGAELCDESYPALLTDIPVGDLHPGEQLEKTVYVRCGTVGSRMFLVYVSYLINTTVEGKEIICKCHKDDTVTIETVFPFDVAVRFVSTKFEHLERVYADIPFLLMTDVLSASPWALTIVSSELQLAPSMTAMDHLESQIDKVVLQTGESASECFCLRCPSAGNIEGGVATGHYIISWKRASVVESIPAVSTVITLPHVIAENIPLHVNADLPSFGRVRESLPVRYHLQNKTDLVQDVEISVEPSDAFMFSGLKQIRLRILPGTKQEMLYNFYPLMAGYQQLPSLNINLLRFPNFTNQLLRRFIPTSIFVKPQGRLLEDTSIAAA
What is the function of this protein?
Involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage.
What are the official names of this protein?
Trafficking protein particle complex subunit 11.
What is the protein family that this protein belongs to?
Belongs to the TRAPPC11 family.
What are the subcellular locations of this protein?
Golgi apparatus. Golgi apparatus, cis-Golgi network.
Protein: CAF17_HUMAN
Sequence: MATAALLRGATPGRGGPVWRWRLRAAPRCRLAHSSCSPGGDPTAGAAWACFRLDGRTLLRVRGPDAAPFLLGLLTNELPLPSPAAAGAPPAARAGYAHFLNVQGRTLYDVILYGLQEHSEVSGFLLECDSSVQGALQKHLALYRIRRKVTVEPHPELRVWAVLPSSPEACGAASLQERAGAAAILIRDPRTARMGWRLLTQDEGPALVPGGRLGDLWDYHQHRYLQGVPEGVRDLPPGVALPLESNLAFMNGVSFTKGCYIGQELTARTHHMGVIRKRLFPVRFLDPLPTSGITPGATVLTASGQTVGKFRAGQGNVGLALLWSEKIKGPLHIRASEGAQVALAASVPDWWPTVSK
What is the function of this protein?
Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway.
What are the official names of this protein?
Putative transferase CAF17, mitochondrial, Iron-sulfur cluster assembly factor homolog.
What is the protein family that this protein belongs to?
Belongs to the GcvT family. CAF17 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TSAD_SALPC
Sequence: MRVLGIETSCDETGIAIYDDKKGLLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQAALKEAGLTASDIDAVAYTAGPGLVGALLVGATVGRSLAFAWNVPAIPVHHMEGHLLAPMLEDNPPDFPFVALLVSGGHTQLISVTGIGQYELLGESIDDAAGEAFDKTAKLLGLDYPGGPMLSKMASQGTAGRFVFPRPMTDRPGLDFSFSGLKTFAANTIRSNGDDEQTRADIARAFEDAVVDTLMIKCKRALESTGFKRLVMAGGVSANRTLRAKLAEMMQKRRGEVFYARPEFCTDNGAMIAYAGMVRFKAGVTADLGVTVRPRWPLAELPAA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALF1_ECOL6
Sequence: MTDIAQLLGKDADNLLQHRCMTIPSDQLYLPGHDYVDRVMIDNNRPPAVLRNMQTLYNTGRLAGTGYLSILPVDQGVEHSAGASFAANPLYFDPKNIVELAIEAGCNCVASTYGVLASVSRRYAHRIPFLVKLNHNETLSYPNTYDQTLYASVEQAFNMGAVAVGATIYFGSEESRRQIEEISAAFERAHELGMVTVLWAYLRNSAFKKDGVDYHVSADLTGQANHLAATIGADIVKQKMAENNGGYKAINYGYTDDRVYSKLTSENPIDLVRYQLANCYMGRAGLINSGGAAGGETDLSDAVRTAVINKRAGGMGLILGRKAFKKSMADGVKLINAVQDVYLDSKITIA
What are the official names of this protein?
Fructose-bisphosphate aldolase class 1, Fructose-bisphosphate aldolase class I, FBP aldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. FbaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1617_STRP8
Sequence: MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENALIGVNDHTLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGVSYYCNLASPYMMDTEALKYIDYDLDVKVFADGEKRLLDVDEYEIHKKEMQYSADMDFILKENVKILVDWINHEKGPFSKAYITIWYKRYLELKNR
What are the official names of this protein?
UPF0374 protein spyM18_1617.
What is the protein family that this protein belongs to?
Belongs to the UPF0374 family.
Protein: RL2_CELJU
Sequence: MAIVKSKPTSPGRRFVVKVVNHDLHKGEPYAPLLDKKSKSGGRNNTGRITTRHVGGGHKQHYRIVDFRRNKDGIPATVERIEYDPNRTAYIALVVYADGERRYIIAPKGLSAGDKIESGNAAAIKVGNTLPVRNIPLGSVIHCVELKPGKGAQLARSAGASAQLVAKDGAYVTLRLRSGEMRKVLSDCRATLGEVSNTEHNLRSLGKAGAKRWLGIRPTVRGVAMNPVDHPHGGGEGRTSGGRHPVSPWGIPTKGYKTRKNKRTDNMIVRRRDKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RPOA_CORJK
Sequence: MLISQRPALTEEFIDDSRSRFVIEPLEPGFGYTLGNSLRRTLLSSIPGAAVTSLRIEGVLHEFTTIPGVKEDVSDIILNIKSLVLSSDSDEPVSMFIRKEGPGEVTGADVEVPAGVEVHNQDLHIATLNEQGKLEIEMTVERGRGYVPAATASSEIGRIPVDQIYSPVLKVSYKVEATRVEQRTDFDKLILDVETKNSITARDAMASAGKTLVELFGLAQELNHEAEGIEIGPSPQESEHIAAYSMPIEDLNFSVRSYNCLKREEIHTVGELAARTESDLLDIRNFGQKSINEVKVKLAGLGLGLKDAPEGFDITDIEGYDAETGEFIDTEGEDIAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: I22R2_HUMAN
Sequence: MMPKHCFLGFLISFFLTGVAGTQSTHESLKPQRVQFQSRNFHNILQWQPGRALTGNSSVYFVQYKIMFSCSMKSSHQKPSGCWQHISCNFPGCRTLAKYGQRQWKNKEDCWGTQELSCDLTSETSDIQEPYYGRVRAASAGSYSEWSMTPRFTPWWETKIDPPVMNITQVNGSLLVILHAPNLPYRYQKEKNVSIEDYYELLYRVFIINNSLEKEQKVYEGAHRAVEIEALTPHSSYCVVAEIYQPMLDRRSQRSEERCVEIP
What is the function of this protein?
Isoform 1 may play a role in establishing and maintaining successful pregnancy.
What are the official names of this protein?
Interleukin-22 receptor subunit alpha-2, IL-22 receptor subunit alpha-2, IL-22R-alpha-2, IL-22RA2, Cytokine receptor class-II member 10, Cytokine receptor family 2 member 10, CRF2-10, Cytokine receptor family type 2, soluble 1, CRF2-S1, Interleukin-22-binding protein, IL-22BP, IL22BP, ZcytoR16.
What is the protein family that this protein belongs to?
Belongs to the type II cytokine receptor family.
What are the subcellular locations of this protein?
Secreted.