PharMolix/UniProtQA huggingface dataset:
Protein: DEOB_ECOUT
Sequence: MKRAFIMVLDSFGIGATEDAERFGDVGADTLGHIAEACAKGEADHGRKGPLNLPNLTRLGLAKAHEGSTGFIPAGMDGNAEVIGAYAWAHEMSSGKDTPSGHWEIAGVPVLFEWGYFSDHENSFPQELLDKLVERANLPGYLGNCHSSGTVILDQLGEEHMKTGKPIFYTSADSVFQIACHEETFGLDKLYELCEIAREELTNGGYNIGRVIARPFIGDKAGNFQRTGNRHDLAVEPPAPTVLQKLVDEKHGQVVSVGKIADIYANCGITKKVKATGLDALFDATIKEMKEAGDNTIVFTNFVDFDSSWGHRRDVAGYAAGLELFDRRLPELMSLLRDDDILILTADHGCDPTWTGTDHTREHIPVLVYGPKVKPGSLGHRETFADIGQTLAKYFGTSDMEYGKAMF
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATA_DROME
Sequence: MRRHLQWSIKQLTASYSDGQLSPRRVTEDALQDALRWKTLNAFVRLTPEQAGQQAQDAEQRYKLRQPISDLDGVTIAIKDNFCTKDVHTTCASRMLQDFVPPYDATVCSRLKQAGAVILGKTNMDQFAMGAGTVDSLYGPTKNIWSEDLNKDHWRIAGGSSGGSASAVAAGLCYAAIGSDTGGSTRNPASYCGVVGLKPTYGLVSRHGLIPLVNSMDVPGIFARSVSDCVAVLNTVAGPDKLDSTTIRQPFTRLHLPEVGQIDLSTVRIGIPKEYHCHGLSAEVLETWSKVADLLECSGASVRQVSLPNTAASIFVYTILNQCEVASNMARYDGIEYGHRATDERSTEQLYALSRAEGFNDVVKTRILTGNFLLLKKNYDHYFEKALRVRRLIAEDFARVFDSSAKEERVDILLTPTTLTEAPLYKDFASLTNRDQCAVQDFCTQPANMAGIPAVSIPIRLSQAGLPLSLQLMSNSLNEQLLLTVARWIEAQVEFDSLEHSQQYKASL
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial, Glu-AdT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ESSA_STAAC
Sequence: MLMNSVIALTFLTASSNNGGLNIDVQQEEEKRINNDLNQYDTTLFNKDSKAVNDAIAKQKKERQQQIKNDMFQNQASHSTRLNETKKVLFSKSNLEKTSESDKSPYIQNKQEKKIFPYILMSVGAFLTLGFVIFSIHKGRRTKNESARKSNI
What is the function of this protein?
Component of the ESAT-6 secretion system (Ess).  Required for the secretion of EsxA and EsxB.
What are the official names of this protein?
ESAT-6 secretion machinery protein EssA.
What is the protein family that this protein belongs to?
Belongs to the EssA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: HCY1_HOMAM
Sequence: GTTVVAHKQQSVNRLLYKVTSHIPDTFFSLK
What is the function of this protein?
Hemocyanins are copper-containing oxygen carriers occurring freely dissolved in the hemolymph of many mollusks and arthropods.
What are the official names of this protein?
Hemocyanin subunit 1.
What is the protein family that this protein belongs to?
Belongs to the tyrosinase family. Hemocyanin subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: ISPD_BACCR
Sequence: MYTLIIPAAGQGKRMGAGKNKLFLLIDEVPIIVHTLRAFEKDKACKSIIMAINEEERPYFEELMQKYQIEKHVQFIQGGAERQDSVYNALQYASGVEYVLVHDGARPFVTNKVIRDVLTAAEKYGASICAVPVKDTVKKVEQGVVVETVERSQLNAVQTPQGFSVSLLLEAHRSAKQSCFLGTDDASLVERVGKQVGVVEGSYYNIKVTTPEDLLIAESFLRVQKK
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: HIS4_SHEPW
Sequence: MIIPAIDLIEGQVVRLYQGDYNQKTTFNLSPLEQLQSYQEQGADLLHIVDLTGAKDPMKRQTQLIASLVRELDTPIQVGGGVRTEAQLSELLEIGVSRVVIGSLAVKEPELVKSWFVKYGSDAICLALDVNINDQGEKIVAVSGWQSGGGKTLESLVAEFSTVGLKHALVTDISRDGTLKGANTELYQEISTAYPEINWQASGGIATLADVNAVKESGANGIIIGKALLINQFTVEEAITCWPNA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_STRZJ
Sequence: MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPEREGLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVSHIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLREYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFYKSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELNAPGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLGKRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVERGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNADFDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEAGREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKILFNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNIIAEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISNFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSGYLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPETGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVITEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGSIQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDTDLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTRVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEGNEETTEVVVDTAVETVEETVE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: PFKA_SALDC
Sequence: MIKKIGVLTSGGDAPGMNAAIRGVVRAALTEGLEVMGIYDGYLGLYEDRMVQLDRYSVSDMINRGGTFLGSARFPEFRDENIRAVAIENLKKRGIDALVVIGGDGSYMGAKRLTEMGFPCIGLPGTIDNDIKGTDYTIGYFTALGTVVEAIDRLRDTSSSHQRISIVEVMGRYCGDLTLAAAIAGGCEFIVVPEVEFNREDLVAEIKAGIAKGKKHAIVAITEHMCDVDELAHFIEKETGRETRATVLGHIQRGGSPVPYDRILASRMGAYAIDLLLEGHGGRCVGIQNEQLVHHDIIDAIENMKRPFKSDWMECAKKLY
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_CLOBK
Sequence: MAAGMKGKRSRRRKERKNVEHGCAHIKSTFNNSIVTITDSVGNTLSWASAGGLGFRGSRKSTPFAAQMAAETAAKAAMEHGLKSIEVYVKGPGSGREAAIRSLQAAGLEVTLIKDVTPIPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: CUTC_SALPK
Sequence: MALLEICCYSMECALTAQRNGADRIELCAAPKEGGLTPSFGILRSVREHITIPVHPIIRPRGGDFYYTDGEFAAMLEDIRLVRELGFPGLVTGVLTVDGDVDMSRMEKIMTAAGPLAVTFHRAFDMCANPFNALKNLADAGVARVLTSGQKADAAQGLSIIMELIAQGDAPIIMAGAGVRANNLQNFLDAGVREVHSSAGVLLPSPMRYRNQGLSMSADIQADEYSRYRVEGAAVAEMKGIIVRHQAK
What are the official names of this protein?
PF03932 family protein CutC.
What is the protein family that this protein belongs to?
Belongs to the CutC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CITC_MONRU
Sequence: MATVKVIDFIQTPFDFLIVGGGTAGLVLAARLSEEPGIQVGVIEAGSLRLGDPKVDLPTGPGQMLGDPGYDWNFESIPQAGANAKAYHIPRGRMLGGSSGINFMSYNRPSAEDIDDWANKLGVKGWTWSELLPYFKRSENLEPIEPSASCPVSPKVHGTGGPIHTSIGPWQAPIEESLLAAFDEAARLQRPAEPYSGAHLGFYRSLFTLDRTSTPVRSYAVSGYYAPVMGRPNLKVLENAQVCRILLSDASDGIPVAEGVELHHAGARYAVSARREVILSAGSVQSPQLLELSGIGDPSVLEGAGIACRVANTDVGSNLQEHTMSAVSYECADGIMSVDSLFKDPALLEEHQSLYAKNHSGALSGSVSLMGFTPYSSLSTETQVDATMARIFDAPSVSGRLSQQNASYQRRQQEAVAARMQNRWSADIQFIGTPAYFNTAAGYASCAKIMSGPPVGYSACYSIVVSNMYPLSRGSVHVRTSNPMDAPAIDPGFLSHPVDVDVLAAGIVFADRVFRSTLLNGKVRRRVSPPAGLDLSNMDEARQFVRNHIVPYHHALGTCAMGQVVDEKLRVKGVRRLRVVDASVMPMQVSAAIMATVYAIAERASDIIKKDCGFGRRLRAHI
What is the function of this protein?
Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of the mycotoxin citrinin, a hepato-nephrotoxic compound to humans due to inhibition of respiration complex III (Ref. 1).  The pathway begins with the synthesis of a keto-aldehyde intermediate by the citrinin PKS (pksCT also named citS) from successive condensations of 4 malonyl-CoA units, presumably with a simple acetyl-CoA starter unit (Ref. 1).  Release of the keto-aldehyde intermediate is consistent with the presence of the C-terminal reductive release domain (Ref. 1).  CitA collaborates with citS by catalyzing the hydrolysis of ACP-bound acyl intermediates to free the ACP from stalled intermediates (PubMed:29189834).  CitB then catalyzes the oxidation of the C-12 methyl of the ketone intermediate to an alcohol intermediate which is further oxidized by the oxidoreductase citC to produce a bisaldehyde intermediate (Ref. 1).  The fourth catalytic step is catalyzed by the citD aldehyde dehydrogenase (Ref. 1).  The final transformation is the reduction of C-3 by citE to provide the chemically stable citrinin nucleus (Ref. 1).  CitE appears highly selective for its substrate as its presence in any context other than a full complement of citS and citA-D does not result in observable new compounds (Ref. 1).
What are the official names of this protein?
Dehydrogenase citC, Citrinin synthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: DCUP_SERP5
Sequence: MNELKNDRYLRALLRQPVDVTPVWMMRQAGRYLPEYKATRAQAGDFMSLCKNAELACEVTLQPLRRFPLDAAILFSDILTIPDAMGLGLYFETGEGPRFSSPITSRADVDKLPAFDPEVELGYVMNAVRTIRRELKGEVPLIGFSGSPWTLATYMVEGGSSKAFTKLKKMMYAEPATLHLLLDKLADSVILYLNAQIKAGAQSVMVFDTWGGVLTGRDYREFSLHYMHKIVDGLLRENDGRRVPVTLFTKGGGQWLEAMAATGCDALGLDWTTDIADARRRVGDKVALQGNMDPSMLYASPERIGQEVETILAGFGHGEGHVFNLGHGIHPDVPPENAGAFVEAVHAQSGKYHR
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRT5_YEAS7
Sequence: MTEQVNNDTTSDTTTTITTVYISNLPFTASERDLHAFLNNYGASSVLIPTQTVRRFSKRHNSNPRKPLGIAFAQFANNTLALKAIQDLNGTVFQNQKLFLKLHVPYEADSTPDTDVKKPKEKNKVKKTPETAADTVYCHDLPDDITDSEIRELFQLYSPQEIWIYRSKVYRRKCIPFAPHQITAALVTLQSETPIGDICDSVAKTATLRGKSIIVKPAYVSKIQEIKQLVKDNLTNARDPPPAALAEPAPAPAPVEPAEQVQEGQDNAETNDVPPPPASSSDRPTVAAT
What is the function of this protein?
May be involved in the modulation of rDNA transcription.
What are the official names of this protein?
Regulator of rDNA transcription protein 5.
What is the protein family that this protein belongs to?
Belongs to the RRT5 family.
Protein: GPDA_AYWBP
Sequence: MIKRKKLYFMKITIIGSGAWGSTLAQVLTDNNNQVLLYDTNLSYVEKINQGKHPIFNTPLLNVKAVSCLKQTLEYSDLIVLAVPMKFMRHLLKKITLMLTNPKSFVNVSKGIEPLTFLRVSEIVKQVIPAPLLANFASLMGPSHAEEVILRKLTLLTAASSNPVFSLEIQKLFSCPNYLKVYTSSDLVGNEICSAFKNILALINGILVAKDFGINSQAALMSRGILEMSRLVTFYQGNPQTVLGLPGLGDLIVTAFSKYSRNFNAGAKIAAGIPYQQIIDSSLQTVEGFQTLNAFYQLQLKHNLDLPIIQASYQLIFESKPFDTVFATLIQRPYKSEF
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYT1_ARATH
Sequence: MADQQAGTIVGGVRDIDANANDLQVESLARFAVDEHNKNENLTLEYKRLLGAKTQVVAGTMHHLTVEVADGETNKVYEAKVLEKAWENLKQLESFNHLHDV
What is the function of this protein?
Involved in suppression of hypersensitive cell death activated by either avirulent pathogen or oxidative stress.
What are the official names of this protein?
Cysteine proteinase inhibitor 1, AtCYS-1.
What is the protein family that this protein belongs to?
Belongs to the cystatin family. Phytocystatin subfamily.
Protein: SECB_RICFE
Sequence: MSTINTDTNEAMPHISVNAQYIKDLSLENPSAPSSLAALEQRPQIDLSLDINITNLSEENFYEVELNIEATARNEKYKLFQIELKYAGVFNLINIDSEQHPILLSVHCPAMIFPFARKIIASCTQDAGFQPLMIDPIDFGALYHKKMSEHQN
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSGA_ENT38
Sequence: MTNSNRIKLTWISFFSYALTGALVIVTGMVMGDIANYFQLPVSSMSNTFTFLNAGILISIFLNAWLMEIVPLKTQLRFGFVLMVAAVAGLMVSHSIALFSVSMFVLGLVSGITMSIGTFLITHMYEGRQRGARLLFTDSFFSMAGMIFPMVAAVLLARSIEWYWVYACIGLVYVAIFVLTFGCEFPVLGKKAEQSTQPVAKEKWGIGVLFLSVAALCYILGQLGFISWVPEYAKGLGMSLNDAGKLVSDFWMSYMFGMWAFSFILRFFDLQRILTVLAGLATVLMYLFINGAPEHMAWFILTLGFFSSAIYTSIITLGSLQTKVASPKLVNFVLTCGTIGTMLTFVVTGPIVAHSGPLAALQTANGLYAVVFVMCLILGFVTRHRQHNTVAASH
What are the official names of this protein?
Protein TsgA homolog.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TsgA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DNLJ_PARMW
Sequence: MAEQQQRAAELRSLLNRAAHAYYVLDAPVMEDTLYDRLYRELQQLEQADPSLLSADSPTQRVGKAPATGFHSVEHRIPLQSLDNAFDHGELKAWHERLLKVLDRADDSPLPLVGELKIDGNALALSYRHGVLERAATRGDGSSGEEITANVRTISSIPLRLQIDDPPEWVEVRGEAFIPDDTFAAINNERAAHGDALFANPRNACAGTLRQLDPKVVAARRLDFFAYTLHLPSDHSNSPECQWDVLAWLEQAGFRVNPNRELCDGLNGIERFCDRWEQQRHQLTYATDGVVVKLNDLRLQDEAGTTQKAPRWAIALKYPAEEAPSKLLKLAVQVGRTGAVTPVAEFEPVALAGTSVSRATLHNADRIAELDLHLGDTVVVRKAGEIIPEVVRVLPELRPTGAVPLELPDHCPECGSNLVRDDSEAATRCINSSCPAILRGGLRHWVSKGALDVDGLGNKLIQQLVERGLVRSIADLYRLDAALLASLERVGEKSAANLVAALEQSKQQPWHRQLYGLGIRHIGEVNAKALAAAYPNSASLAAAEPESIAALHGIGPEISSSLQQWHANPPNQRLLEDLRAVGLSLEANTSELNANSTGEGNSSGALLGKTLVLTGTLPNLSRSDAKTLIEGAGGKVSGSVSKKTDYLVAGEAAGSKLSKAESLGVEILTEAELQKLLST
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: PURT_SYNS3
Sequence: MTNFPKTVMLLGSGELGKEVAIAAQRLGCHVIACDRYADAPAMQVADQAEVLTMTDPNALKTVVNKHQPDVLIPEIEALAVDALQALEDTGICVIPTARATAVTMNRDRIRNLAAGELGLRTARFAYASDAQELQRAAAPLGWPVVVKPVMSSSGKGQSVVHSAAELDKAWEIAMAGARGSSAQVIVEEFLDFDLEITLLTIRQHDGTTLFCPPIGHQQANGDYQCSWQPASISPSQLQQAQTMARTVTDNLGGAGLFGVEFFLCGDEVVFSELSPRPHDTGLVTLISQNLSEFDLHLRAVLGLPIPSITAADAAASRVILAESQGHHVQFSGVEQALTEPDTNLLLFGKREARPGRRMGVALARGTQINEALAKADRCAAAVKVQVMD
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: REGA_CLOAB
Sequence: MAASIKDVAREARVSIATVSRVLNNVDVVNEETKKKVMEAIKKLDYRPNIVARSLKTQRTRTIGIVIPDISSQFYPEIVRGAEDVSNIYNYNVILCNTDLDISKEKDYIRVLKEKMVDGVIYMSNSLAPEILQLLRDLKIPTVLVETRESEDENAFPSVTIDNAKAAYDAVNYLIKKGNNKIAYVGVNPKLKNNARAIIYEGYKKALLDNNIPLNENLIQFGGLKAIDGTDGINVIIKKEKIDAVFCACDEIAMGAINALRENGIDVPKDVDVVGFDNIYTSSIFYPKLTTIEQPTYDMGSVGMRMLIKIINKAEPECLHYVLDYNIIERDSCK
What is the function of this protein?
Involved in the regulation of amylase production.
What are the official names of this protein?
HTH-type transcriptional regulator RegA.
Protein: H2A_PODAS
Sequence: MTGGGKSGGKASSGKNAQSRSSKAGLAFPVGRVHRLLRKGNYAQRVGAGAPVYLAAVLEYLAAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGHVTIAQGGVLPNIHQNLLPKKTGTKPGKNASQEL
What is the function of this protein?
Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RS27_PYRFU
Sequence: MAKPIIPMPRSRFLRVKCIDCGNEQIVFSHPATKVRCLICGATLVEPTGGKGIVKAKILEVLE
What are the official names of this protein?
30S ribosomal protein S27e, Small ribosomal subunit protein eS27.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS27 family.
Protein: DXR_MYCTO
Sequence: MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: YB131_YEAST
Sequence: MTLRHYFFLQDYKRNVENLPFYKNQATLQ
What are the official names of this protein?
Putative uncharacterized protein YBR131C-A.
Protein: CDPKH_ARATH
Sequence: MGNCCSHGRDSADNGDALENGASASNAANSTGPTAEASVPQSKHAPPSPPPATKQGPIGPVLGRPMEDVKASYSLGKELGRGQFGVTHLCTQKATGHQFACKTIAKRKLVNKEDIEDVRREVQIMHHLTGQPNIVELKGAYEDKHSVHLVMELCAGGELFDRIIAKGHYSERAAASLLRTIVQIVHTCHSMGVIHRDLKPENFLLLNKDENSPLKATDFGLSVFYKPGEVFKDIVGSAYYIAPEVLKRKYGPEADIWSIGVMLYILLCGVPPFWAESENGIFNAILRGHVDFSSDPWPSISPQAKDLVKKMLNSDPKQRLTAAQVLNHPWIKEDGEAPDVPLDNAVMSRLKQFKAMNNFKKVALRVIAGCLSEEEIMGLKEMFKGMDTDSSGTITLEELRQGLAKQGTRLSEYEVQQLMEAADADGNGTIDYGEFIAATMHINRLDREEHLYSAFQHFDKDNSGYITMEELEQALREFGMNDGRDIKEIISEVDGDNDGRINYDEFVAMMRKGNPDPIPKKRRELSFK
What is the function of this protein?
May play a role in signal transduction pathways that involve calcium as a second messenger.
What are the official names of this protein?
Calcium-dependent protein kinase 17.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily.
What are the subcellular locations of this protein?
Membrane; Lipid-anchor.
Protein: ATPE_DESVV
Sequence: MEKSLHLEIVTPDKLVLSEQVDYVGAPGFEGEFGVLPSHIPFLSALAIGSLYYKANGKTHHVFVSGGFAEVSDNKVTVLAESAERAEDIDIDRARKAKDRAEQRLAQIKEKVDHARAQAALQRALARMRVRGNA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ABRX2_HUMAN
Sequence: MAASISGYTFSAVCFHSANSNADHEGFLLGEVRQEETFSISDSQISNTEFLQVIEIHNHQPCSKLFSFYDYASKVNEESLDRILKDRRKKVIGWYRFRRNTQQQMSYREQVLHKQLTRILGVPDLVFLLFSFISTANNSTHALEYVLFRPNRRYNQRISLAIPNLGNTSQQEYKVSSVPNTSQSYAKVIKEHGTDFFDKDGVMKDIRAIYQVYNALQEKVQAVCADVEKSERVVESCQAEVNKLRRQITQRKNEKEQERRLQQAVLSRQMPSESLDPAFSPRMPSSGFAAEGRSTLGDAEASDPPPPYSDFHPNNQESTLSHSRMERSVFMPRPQAVGSSNYASTSAGLKYPGSGADLPPPQRAAGDSGEDSDDSDYENLIDPTEPSNSEYSHSKDSRPMAHPDEDPRNTQTSQI
What is the function of this protein?
Component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked polyubiquitin, leaving the last ubiquitin chain attached to its substrates (PubMed:19214193, PubMed:20032457, PubMed:20656690, PubMed:24075985).  May act as a central scaffold protein that assembles the various components of the BRISC complex and retains them in the cytoplasm (PubMed:20656690).  Plays a role in regulating the onset of apoptosis via its role in modulating 'Lys-63'-linked ubiquitination of target proteins (By similarity).  Required for normal mitotic spindle assembly and microtubule attachment to kinetochores via its role in deubiquitinating NUMA1 (PubMed:26195665).  Plays a role in interferon signaling via its role in the deubiquitination of the interferon receptor IFNAR1; deubiquitination increases IFNAR1 activities by enhancing its stability and cell surface expression (PubMed:24075985, PubMed:26344097).  Down-regulates the response to bacterial lipopolysaccharide (LPS) via its role in IFNAR1 deubiquitination (PubMed:24075985).  Required for normal induction of p53/TP53 in response to DNA damage (PubMed:25283148).  Independent of the BRISC complex, promotes interaction between USP7 and p53/TP53, and thereby promotes deubiquitination of p53/TP53, preventing its degradation and resulting in increased p53/TP53-mediated transcription regulation and p53/TP53-dependent apoptosis in response to DNA damage (PubMed:25283148).
What are the official names of this protein?
BRISC complex subunit Abraxas 2, Abraxas brother protein 1, Protein FAM175B.
What is the protein family that this protein belongs to?
Belongs to the FAM175 family. Abro1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton. Note=A minor proportion is detected in the nucleus (PubMed:21282113, PubMed:22974638). Translocates into the nucleus in response to DNA damage (PubMed:25283148). Directly binds to microtubules and is detected at the minus end of K-fibers (PubMed:26195665). Co-localizes with NUMA1 at mitotic spindle poles (PubMed:26195665).
Protein: RS21_SALEP
Sequence: MPVIKVRENEPFDVALRRFKRSCEKAGVLAEVRRREFYEKPTTERKRAKASAVKRHAKKLARENARRTRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.