PharMolix/UniProtQA huggingface dataset:
Protein: HOXA_BRADU
Sequence: MSIQGTILVVDDEVRSQEALRRVLREDFEVLCVGNATDAEKLLEGEIVHAILCDQRMPHESGVSFLKRVRELWPDPVRMIISGYSESEDIIAGLNEAGIYQYITKPWQPDQLVETVKEAVQLYRLQKETETAGVDVKATSGHIKKVVSVKRGVAKQLYDFDRIVHSTESPMHAVIELGRRAADYDISVLITGESGTGKELLARAIHYGSARANRAFVVENCGALPDELLESELFGCKKGAFTGAYQDRIGLFEVADGGTIFLDEIGETSPAFQVKLLRVLQESEIRPLGAQRVRKVDVRVVAATNRDLEAEVEAGRFRRDLYYRLAAFPVHMPALRERPMDIPLIAEGVLSAVKSSFNRPNLRFARSALEEFGKYHWPGNVRELQNEIQRMAVLADRDELAAPPLLGRRNGKRSAPLPAHGRLNGSASLKDKVEDLEKSVIMNCLERNDGNISRVASELGLSRVGLRNKLSRYDLRKNAKGDAFS
What is the function of this protein?
Probable member of the two-component regulatory system involved in the regulation of the hydrogenase activity.  HoxA is probably phosphorylated by a sensory component (which could be HoxX) and then acts in conjunction with sigma-54 as a transcriptional activator.
What are the official names of this protein?
Hydrogenase transcriptional regulatory protein HoxA.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14_CHLL2
Sequence: MAKKSIIARNEKRKKLVEKYAAKREELLKAGDYEALRKLPRDSSATRVKNRCVLTGRGRGVYEKFGLCRQMFRKFALEGKLPGVKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: CYB_TYPNA
Sequence: MAPTMRKTHPLLKIINNSLIDLPTPSNISYLWNYGSLLGLCLMTQILTGLFLAMHYTADTATAFSSLAHICRDVNYGWLMRNIHANGASFFFICIYLHIGRGIYYGSYLFKETWNIGVILLLLVMATAFVGYVLPWGQMSFWGATVITNILSAIPYIGNNLVQWVWGGFAVDNATLTRFFTFHFLLPFLIAGTSMLHLLFLHETGSNNPTGLNSNSDKIPFHPYFSYKDTFGFMIMLAALALLSTTNPNLMSDPENFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLFSIMILMLIPSLHTAKQRSMMFRPLSQLMFWSIIANTLVLTWIGGQPVEDPFILIGQISSALYFILFLVLLPLTNWSDNKMLNL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PLAT1_DANRE
Sequence: MDNQQRRTDNMASGETDHLQCVEEPQPGDLIEIFRPAYQHWALYLGDGYIINLTPVDEGQATAVSSVKSVFSRKAVVRMQLLKEVVGADSYRINNKYDDDHTPLPVSEIIQRAQMLIGQEVSYDLLGSNCEHFVTLLRYGEGVSEQASRAIGAISLVTAAASAFSVLGLINTRSRNRPF
What is the function of this protein?
Exhibits both phospholipase A1/2 and acyltransferase activities.  Shows phospholipase A1 (PLA1) and A2 (PLA2) activity, catalyzing the calcium-independent release of fatty acids from the sn-1 or sn-2 position of glycerophospholipids.  Shows O-acyltransferase activity, catalyzing the transfer of a fatty acyl group from glycerophospholipid to the hydroxyl group of lysophospholipid.  Shows N-acyltransferase activity, catalyzing the calcium-independent transfer of a fatty acyl group at the sn-1 position of phosphatidylcholine (PC) and other glycerophospholipids to the primary amine of phosphatidylethanolamine (PE), forming N-acylphosphatidylethanolamine (NAPE) which serves as precursor for N-acylethanolamines (NAEs) (By similarity).  Required for complete organelle rupture and degradation that occur during eye lens terminal differentiation, when fiber cells that compose the lens degrade all membrane-bound organelles in order to provide lens with transparency to allow the passage of light (PubMed:33854238).  Organelle membrane degradation is probably catalyzed by the phospholipase activity (PubMed:33854238) (By similarity).
What are the official names of this protein?
Phospholipase A and acyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the H-rev107 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Cytoplasm, cytosol. Mitochondrion membrane; Single-pass membrane protein. Lysosome membrane; Single- pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein. Note=During eye lens differentiation, recruited from the cytosol to various organelles, including mitochondria, endoplasmic reticulum and lysosomes, immediately before organelle degradation. This translocation is triggered by organelle membrane damage and requires the C-terminal transmembrane domain.
Protein: LASI1_LUPAL
Sequence: IEPERQEEEEEETRQRVRRGQVRQQQQ
What is the function of this protein?
Metalloproteinase inhibitor, active on a globulinase from L. albus seeds, thermolysin and gelatinase B.
What are the official names of this protein?
Metalloproteinase inhibitor 1, LASI-1.
Protein: NAGB_BACC2
Sequence: MNILVVKTPEELAEVGYKLIEEVVKTKENPTLGMATGSSPLGIYAEMRKNKLDTSRVTTVNLDEYVNLPHEDKNSYHYFMQEQLFDHLPFKQTYVPNGMASDLEEECKRYEGILAANPVDLQILGIGENGHIGFNEPGTPFNSPTNIVELTESTRQANLRFFEKEEDVPTHAITMGIGSIMKAKQVLLVAMGAKKAEAVKELLQGEYSEECPATVLQRHPNVTVIADQEALSLCSEAIADEHRQVFTISDLLSDSRVGETAN
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: YHBQ_ECOSE
Sequence: MTPWFLYLIRTADNKLYTGITTDVERRYQQHQSGKGAKALRGKGELTLAFSAPVGDRSLALRAEYRVKQLTKRQKERLVAEGAGFAELLSSLQTPEIKSD
What are the official names of this protein?
UPF0213 protein YhbQ.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: MRAY_ECOLU
Sequence: MLVWLAEHLVKYYSGFNVFSYLTFRAIVSLLTALFISLWMGPRMIAHLQKLSFGQVVRNDGPESHFSKRGTPTMGGIMILTAIVISVLLWAYPSNPYVWCVLVVLVGYGIIGFVDDYRKVVRKDTKGLIARWKYFWMSVIALGVAFALYLAGKDTPATQLVVPFFKDVMPQLGLFYILLAYFVIVGTGNAVNLTDGLDGLAIMPTVFVAGGFALVAWATGNMNFASYLHIPYLRHAGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGIIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISLMLVLIGLATLKVR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LDHB_PELSJ
Sequence: MATLQEKLITPIVAGSTTPNNKITVVGVGQVGMACAISILGKGLCDELALVDVLEDKLKGEMMDLQHGSLFLQTHKIVADKDLRVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIMKYSPNCTILVVSNPVDILTYVTWKLSGLPKHRVIGSGCNLDSARFRHLMAEKLGIHPTSCHGWILGEHGDSSVAVWSGVNVAGVSLQELNPAMGTDKDSENWKEVHKMVVDSAYEVIKLKGYTNWAIGLSVADLIESYVKNLCRVHPVSTMVKGMYGIENEVFLSLPCVLSASGLTSVINQKLKDEEVAQLRKSADTLWSIQKDLKDL
What is the function of this protein?
Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+).
What are the official names of this protein?
L-lactate dehydrogenase B chain, LDH-B.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MA7D3_MOUSE
Sequence: MADPTFAATSSSTSFRGLHERLVAMTQELAEERRHKRGINSSAGANKRSSSTPDGSVLKNDVKQQLAKERREQQKRQQEANKEKQLLEKEQKAKLQYEKQLEEKHRKLKEQKEKDQRRQASAEEKRKQKQAEDTEKFKAVVSRTLERCNRIDQRQKRWSWEGGVMNADKSGKLENKRSSSLSRKDNRLHPRGDMQHVDNTPGMTKYVFRYVTAPVFSSDEIKSSAMFCKPSAKTPVAAKLEKITTKKLDASLRGHVEGLSMMNIEIPPKITIEVPSPPKLEESSEADAEVRLQTMDDISKVKEDASQKVDIKVPTDENIARHPKPNVEELSPVSVDTSSSVELSSIVSVNSSPSLSTGSFSFGSVEISPVVSIDASLETNIDTSPELSMDSGNTKVASEIKTEAPLQARGESRLEASVEGQPEANVEGSPKNPEIDKRNINLTTKKQPLCHIPCYRWPSSSALGCRPPSPLKALQTRKIRPPSPIPVSSKLSTKTSLSYKITPVQNVLYVPNSLGVIATKKETIQKYPIKKEFGNRSMPSAEAIKKAFIQIRHAAYEQSKNEKERLQKEETKQRIARKPEIMAEKLDKVPAEGSLPCQDEQQDKNPTKTFLESPEVQKAELQKGDSAMMKSRDSAEQRKKEQENILQHWQERLERRKASEISFSSEDEADDEGESEDSLEIFPSGGKMLSMKLKKFHKYAKTKPQKLVFLQSGTDEVDTNKNVYFNGDMKAVKQKDPKYSMIQGKGSKLSAKKPPTRPIRSRKTKEGSTAIRPTQSASSNPNHKWVCDKVIDFNQTPFLKTTLTKSNKESPADSKIACQGPQAHLDHRKRTKSVSVPLTNVLSHLHITGRASNLEHPFASVYSRLAFGKEAEESDV
What is the function of this protein?
Promotes the assembly and stability of microtubules.
What are the official names of this protein?
MAP7 domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the MAP7 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, spindle. Note=Localizes to the microtubules throughout mitosis.
Protein: POTG_ECOLI
Sequence: MNDAIPRPQAKTRKALTPLLEIRNLTKSYDGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPSAGQIMLDGVDLSQVPPYLRPINMMFQSYALFPHMTVEQNIAFGLKQDKLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRPKLLLLDEPMGALDKKLRDRMQLEVVDILERVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEPEEIYEHPTTRYSAEFIGSVNVFEGVLKERQEDGLVLDSPGLVHPLKVDADASVVDNVPVHVALRPEKIMLCEEPPANGCNFAVGEVIHIAYLGDLSVYHVRLKSGQMISAQLQNAHRHRKGLPTWGDEVRLCWEVDSCVVLTV
What is the function of this protein?
Part of the ABC transporter complex PotFGHI involved in putrescine uptake (PubMed:8416922, PubMed:23719730).  Responsible for energy coupling to the transport system (PubMed:23719730).  Imports putrescine for maintenance of the optimal concentration of polyamines necessary for cell growth in the presence of glucose (PubMed:23719730).
What are the official names of this protein?
Putrescine transport ATP-binding protein PotG.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: AROE_BACCZ
Sequence: MKQLYGVIGNPIGHSLSPVMHNDAFEHLNMDAHYHAFLVKEEVLGEAVRGLKALGISGFNVTTPHKVAIMDYLDEIDPLAKQIGAVNTVVHKDGKLIGYNTDGIGFVRALQSISNEPLQEKRILLLGAGGASRAIYFSLADVGVKEIDVANRTVDKAKELIAACTATVHSVALSLEKATKEQGNYDIIIQTTTIGMHPRVEHTPLQISSLKKGTIVSDIIYNPFETKILCEAKEQGAIIQNGIDMFVYQGALAFEMWTGCVPNIERMKQLVIRKLGG
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: RBBA_ECOLI
Sequence: MTHLELVPVPPVAQLAGVSQHYGKTVALNNITLDIPARCMVGLIGPDGVGKSSLLSLISGARVIEQGNVMVLGGDMRDPKHRRDVCPRIAWMPQGLGKNLYHTLSVYENVDFFARLFGHDKAEREVRINELLTSTGLAPFRDRPAGKLSGGMKQKLGLCCALIHDPELLILDEPTTGVDPLSRSQFWDLIDSIRQRQSNMSVLVATAYMEEAERFDWLVAMNAGEVLATGSAEELRQQTQSATLEEAFINLLPQAQRQAHQAVVIPPYQPENAEIAIEARDLTMRFGSFVAVDHVNFRIPRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVDPKDIDTRRRVGYMSQAFSLYNELTVRQNLELHARLFHIPEAEIPARVAEMSERFKLNDVEDILPESLPLGIRQRLSLAVAVIHRPEMLILDEPTSGVDPVARDMFWQLMVDLSRQDKVTIFISTHFMNEAERCDRISLMHAGKVLASGTPQELVEKRGAASLEEAFIAYLQEAAGQSNEAEAPPVVHDTTHAPRQGFSLRRLFSYSRREALELRRDPVRSTLALMGTVILMLIMGYGISMDVENLRFAVLDRDQTVSSQAWTLNLSGSRYFIEQPPLTSYDELDRRMRAGDITVAIEIPPNFGRDIARGTPVELGVWIDGAMPSRAETVKGYVQAMHQSWLQDVASRQSTPASQSGLMNIETRYRYNPDVKSLPAIVPAVIPLLLMMIPSMLSALSVVREKELGSIINLYVTPTTRSEFLLGKQLPYIALGMLNFFLLCGLSVFVFGVPHKGSFLTLTLAALLYIIIATGMGLLISTFMKSQIAAIFGTAIITLIPATQFSGMIDPVASLEGPGRWIGEVYPTSHFLTIARGTFSKALDLTDLWQLFIPLLIAIPLVMGLSILLLKKQEG
What is the function of this protein?
Exhibits an intrinsic ATPase activity that is stimulated by both 70S ribosomes and 30S ribosomal subunits.  Could be involved in protein-chain elongation and in release of deacyl-tRNA from ribosomes after peptide bond synthesis.  Stimulates the synthesis of polyphenylalanine in vitro.
What are the official names of this protein?
Ribosome-associated ATPase, Ribosomal bound ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y2142_RHIWR
Sequence: MAGHSKFKNIMHRKGAQDKKRSALFSKLSREITVAARMGLPDPAMNARLRQAVITARKEGLPKDNIERSINKAAGGDGANYEEIRYEGFGPGGVALIIEALTDNRNRTATNVRTIVSKNGGNLGAGGSVSHGFDRLGLISYGLAAGDAEKVFEAALEAGADDVSSSEDGHEIWTAQDALHEVAKALEPVLGEPDGAKLAWRPQTQVTVGEDDAAKLLKLIDALDDDDDVQTVWGNYDVPEEVMAKLG
What are the official names of this protein?
Probable transcriptional regulatory protein Swit_2142.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRD_ROSS1
Sequence: MTSLYALIRPLLFRLDAERAHDLTAKALRVTSRAPLLPRLIRALYAWEDPLLAVDWSGLHFANPVGVAAGFDKRADLVDGLALLGFGHIEVGTVTPRPQPGNPRPRLFRLPEDTALINRLGFNSPGMVAVARALRARRSRDVIVGVNIGKNRDTPLERAVEDYVATFVALAPIADYVAVNISSPNTPGLRRLHERAALETLLHELTRLNRALPHPRPIALKVSPDETPDQLEAVVRAGCDAGIAAFIATNTTLARDDLHSRLAIETGGLSGRPLTQRARQVIGAIYRLTHGAPPVIGVGGIATAEDAYQHIRAGARLIQIYTGMVYAGPAIARDIKQGLARRLRRDGFTSLEEAVGVMVAA
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PSBM_PEA
Sequence: MEVNILAFIATALFILVPTAFLLIIYVKTVSQSD
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface.
What are the official names of this protein?
Photosystem II reaction center protein M, PSII-M.
What is the protein family that this protein belongs to?
Belongs to the PsbM family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: ETFA_SCHPO
Sequence: MLRTTSRTFSRALSSSNFKINCGRRHWFSVLTLLEHQGGNLSPASLSAVEAAKRTGGDVFGFVIGKDSSQISQKVAKSVNDLKKVIYVENPSYEHNIPDQIANVLFENVKKNEISHVFSAHSTVGKGVMPRLAAMFDVMQISDIIGVVSADTFVRPTYAGNVNVTVSTKDPIKIVTVRASAFDAAPSSGEGAATVVEGIDPKPAALQEWVSENIIKNARPDLSSAERVVAGGRPLKDKETFERILTPLADKLGAAIGATRVAVDSGYADNSLQIGQTGKIIAPKLYIAVGIDGAIQHLAGIKDSKVIAAINRDENAPIFQTADVGIVGDLFEIVPELTEKL
What is the function of this protein?
The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase.  It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity).
What are the official names of this protein?
Probable electron transfer flavoprotein subunit alpha, mitochondrial, Alpha-ETF.
What is the protein family that this protein belongs to?
Belongs to the ETF alpha-subunit/FixB family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: SYS_LISW6
Sequence: MLDVKLLRNNFEEVKQKLQNRGEDLGEFEKFGELDKRRRTLIVETEALKSQRNEVSQEIAKLKREKQDADAKIEEMRVVGDRIKTLDIELREIDEKLDMILMSIPNIPHESTPVGESEDDNVEIRKWGEVRTFDFEPKAHWDLGTDLDILDFENAAKVTGSRFVFYKKLGARLERALINFMMDLHSNEHGYEEMLPPYMVNRASMTGTGQLPKFEEDAFLIEAEDYFLIPTAEVPVTNYHREDILKAEDLPRKYTAFSACFRSEAGSAGRDTRGLIRQHQFNKVELVQFVKPEDSYEALEKLTSNAEEVLRRLELPYRVLSMCTADLGFTAAKKYDLEVWIPSYDSYREISSCSNFESFQARRANIRFRREPGSKPEYVHTLNGSGLALGRTVAAILENYQDADGSVRIPKVLQGYMGGIEKIELPK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: END8_ECO45
Sequence: MPEGPEIRRAADNLEAAIKGKPLTDVWFAFPQLKSYQSRLIGQHVTHVETRGKALLTHFSNDLTLYSHNQLYGVWRVVDTGEEPQTTRVLRVKLQTADKTILLYSASDIEMLTPEQLTTHPFLQRVGPDVLDPNLTPEVVKERLLSPRFRNRQFAGLLLDQAFLAGLGNYLRVEILWQVGLTGNHKAKDLNAAQLDALAHALLDTPRLSYATRGQVDENKYHGALFRFKVFHRDGEPCERCGGIIEKTTLSSRPFYWCPGCQH
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine.  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Endonuclease 8, DNA glycosylase/AP lyase Nei, DNA-(apurinic or apyrimidinic site) lyase Nei, Endonuclease VIII.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: Y1801_AGGAN
Sequence: MIEWKTFCTIFWQRFNQNKLTQAAGYLTYSTMLAIVPLIMVVFSIFSAFPVFNEVTGALKEFIFTNFAPSASDVVGQYIDEFVNNSKQMSAVGIISLIVVALMLINSIDRTLNSIWHDTSTRPIFTSFAIYWLILTLGPLLVGTSIAASAYVKTMFENASGFSFGLKLLSFVPFLSTWFIFTVIYMVVPNKKVSIKHSAAGALIAAVFFTLGKQAFAWYIVTFPSYQLIYGAMATLPIMLLWIQLSWTFVLLGAQLAAVLAEVRSEKMINLEQIEETK
What are the official names of this protein?
UPF0761 membrane protein NT05HA_1801.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AIM24_PICST
Sequence: MSKSYVSRIVKVGNIKELNFRRSVSISQAPTGIQGDISTTTTYEENIKNAENLKAGNVLETAEFKALGTPQSVLSINCPPSVPVYLRRGSLLSIYGLNDSSSIKNVRSSINFINPIRRLLFGINTSSYQRLESTTPFSLLISATYRKFSIFKKSDNKSFVTISLDGSTDWSILYRDALQVYTGNSLTVSQYRVPRTISRKLSRTLNIPSNTTTGLFKWNKSGFIFLSGRGQVGLVGNGAIYNINLDDKEELLINRDNLLGLTVNGPFDLQNCVVEHNFTTHEKRSESSSVVQKPLGISVILKQQTTVRHKFKQIWSLFQYHLEASFSFLRGSRNKTNNFLVGNQNFVKIIGPRNLLLQSSSETSHIETPTPKRKNGVEVANVTGPKQTSADYLSYVTVTPGQGVKFESTPDFKDTVDKIERK
What are the official names of this protein?
Altered inheritance of mitochondria protein 24, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AIM24 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RGXA_ASPFN
Sequence: MKLSGSSALLLLGFGLLGHASPLVHVQGKNCTVKPLGHGQDDVPNILHAVEKCGQTPGGRISLPAPYTYRINQRMTTHLESSTLEVGGMLLFSDDITYWVNNSYRIDFQNQSTAWRITGHDYVVDGGPERGGIDGNGQLWYTWAKGGSNVFGRPMPLHVLNSTRAVLRNIAIRQPQFWAVLVESSSHVELDNFYVNATNSDPNATEDTVWIQNTDGIDTYRSDHVTITNWVYEGGDDAVAFKPNSTNIHVENVTVYGGPGIAFGSLGQYPDRYDIVENITVKNANFQPSSQRAMNSGIYFKSWIGVNFGVPPNGGGNGHGYVRNVTVEDITFKDVQLPIYIDTCLSYLFDQNVTQYCDTSTFRFDDLHFRNISGNGLATPTNYTGRNITFAVSMICSKEAPCTDITFEDVDIKLPESYSGKSVLCENAGVQGLECNS
What is the function of this protein?
Specific in hydrolyzing the terminal glycosidic bond of polygalacturonic acid and oligogalacturonates.
What are the official names of this protein?
Putative galacturan 1,4-alpha-galacturonidase A, Exopolygalacturonase A, Exorhamnogalacturonase A, Poly(1,4-alpha-D-galacturonide)galacturonohydrolase rgxA.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL7_PROMT
Sequence: MSAKTDEILDSLKSLSLLEASELVKQIEEAFGVSAAASAGVVMAAPGAAAGGDGADAAEEKTEFEVVLESFEASSKIKVLKEVRNATGLGLGEAKALVEAAPKTIKEGATKEDAEALKKAIEAVGGKVTLK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: RL2_AERHH
Sequence: MAIVKCKPTSPGRRHVVKIVNQDLYKGKPFAALLDKKDKSGGRNNNGRITTRHIGGGHKQHYRIVDFKRDKDGIPAKVERLEYDPNRTANIALVLYADGERRYILAPKGLKAGDAIASGADAAIKVGNTLPMRNIPVGSTVHAVEMKPGKGAQLARSAGTFIQILAREGNYVTLRLRSGEVRKVLAECRATIGEVGNSEHMLRQLGKAGANRWRGIRPTVRGMAMNPVDHPHGGGEGRNKGMQPVSPWGQKAKGFKTRKNKRTDKYIVRRRNK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: URE2_PSEAB
Sequence: MIPGEYDIQPGDIELNAGRRTLALSVANTGDRPIQVGSHYHFFEVNDALAFDRPATRGMRLNIAAGTAVRFEPGQSREVELVEIGGGRRVYGFAGRVMGDL
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX1_AEDAE
Sequence: MSRQWLFSTNHKDIGTLYFIFGVWSGMVGTSLSILIRAELSHPGMFIGNDQIYNVIVTAHAFIMIFFMVMPIMIGGFGNWLVPLMLGAPDMAFPRMNNMSFWMLPPSLTLLLSSSMVENGAGTGWTVYPPLSSGTAHAGASVDLAIFSLHLAGISSILGAVNFITTVINMRSSGITLDRLPLFVWSVVITAILLLLSLPVLAGAITMLLTDRNLNTSFFDPIGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIITQESGKKETFGTLGMIYAMLTIGLLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAVPTGIKIFSWLATLHGTQLTYSPALLWSLGFVFLFTVGGLTGVVLANSSIDIVLHDTYYVVAHFHYVLSMGAVFAIMAGFIHWYPLLTGMVMNPSWLKAQFSMMFIGVNLTFFPQHFLGLAGMPRRYSDFPDSYLTWNIISSLGSTISLFAVIFFLFIIWESMITQRTPSFPMQLSSSIEWYHTLPPAEHTYSELPLLSSNF
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.