PharMolix/UniProtQA huggingface dataset:
Protein: UVRB_UREPA
Sequence: MDDFKKFELISDYKPAGDQQKAIDEMVNNINQGIQRQVLLGATGTGKTFSVANVIAKTQLKTLVLAHNKTLAAQLFAELKEMFPHNKVEYFVSYFDYYQPEAYKPITDTYIEKDSVTNAEIEMMRLSTINSLATRNDVIVVASVACIYASVSPIEFTKKNLYLHVGELIEFEQIKYKLVQLGYERKDYDLVPGTFRIRGDLIEIMSGYSDKFKIRISMFGNEVESIDLCDPITNNIISKEQRFILRSASEYIFDDSRLAIAIENIKNELDERVKFFLKNNQLIEAQRIEQRTKQDLESIVEFGFCSGVENYYRHLEHREPFQTPWTIFDFFSYNNQDWLLIVDESHISLPQVKGMHNTDRSRKQTLVEYGFRLPSALDNRPLNYDEFNKKLSKTIYVSATPNDEEIALSDNHIVSQIVRPTGLLDPIIEIRKTEHQIDDLINELMLLKNKNQRAFITVMTIRMAEDLTNYLNNTKIKAAYLHNELKTLERSVIINKLRKGIYDCVVGINLLREGLDVPEVAGVFIFDADKPGFFRSDKSLIQIIGRAARNADGKVIMYADVITQAMQTAINETKRRREIQLAFNLKHNIIPKTIIKPIHEDLSGHDYKQNAELYAAKASKNEYNQKIKELKKKMEEAAKKREYEVAAQYRDMIVELEAIKQSVKSK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA_HELHP
Sequence: MDILQSINDFNEAKQVIPGGVNSPVRAFGSVGGTPRFIAKGKGAYIYDEDDNEYIDFVQSWGPLIFGHANEVIESALSLAIKDGLSFGAPTEKETTLVKQIIALSGSAEKMRLVNSGTEATMSALRLARAYSNKDDIIKFEGCYHGHSDSLLVSAGSGCATFGTPSSPGVPNDITKHTLVARYNDIESVRACFEQSKNVACVIIEALAGNMGFVPADKKFMQDLRALCDEYNALLIIDEVMSGFRAGLKGAIGLYDVQADLVTYGKVIGGGMPLAAFGGRADIMDMLSPVGGVYQAGTLSGNPIAVSAGLATLLQIKANPTLYEHLEVLAKRLIKGLKEAAQSYEIPLQVDCRGSMFGFFFNQKEVKNFDDAKCSDTAMFARFHQKMLDKGVYFACSQFETGFICSAMNEMIIDEVIMKAKAVFGEITHEIESRI
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3SA0_NAJSP
Sequence: MKTLLLTTVVVTIVCLDLEYTLKCNKLVPLFYKTCPAGKNLCYKMFMVATPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN
What is the function of this protein?
Shows cytolytic activity on many different cells by forming pore in lipid membranes.  In vivo, increases heart rate or kills the animal by cardiac arrest.  In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 (KCNIP1) in a calcium-independent manner, and binds to integrin alpha-V/beta-3 (ITGAV/ITGB3) with moderate affinity.
What are the official names of this protein?
Cytotoxin, CTX, Cardiotoxin.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type IA cytotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: RGMG2_AGRFC
Sequence: MVVSPSTMAAVRASGAVPNAEFLLAADGIRKEFPGVVALDDVQFHLKRGTVHALMGENGAGKSTLMKILAGIYQPDNGEIRLKGAPIRLDSPLDALENGIAMIHQELNLMAYMTVAENIWIRREPKNRLGFIDHGEMYRRTETLLERLGIDLDPETRVGELSVASRQMVEIAKAVSYNSDVLIMDEPTSALTEREVEHLFRIIRDLRERGIGIVYITHKMNELFEIADEFSVFRDGKYIGTHASTDVTRDDIIRMMVGREITQMFPKEEVPIGDVVLSVKNLNLDGVFHDVSFDVRAGEILGVAGLVGSGRSNVAETVFGVTPASSGTISIDGKPVSIDSPTTAISHRMAFLTEDRKDTGCLLILNILENMQIAVLQDKYVANGFVQENALSEACEEMCRKLRVKTPHLYERIENLSGGNQQKVLIGRWMLTKPRILILDEPTRGIDVGAKAEIHKLVCEMARQGVAVIMISSEMPEVLGMSDRVMVMHEGRVTGFLARSEATQVKVMDLASR
What is the function of this protein?
Part of an ABC transporter complex involved in carbohydrate import.  Could be involved in ribose, galactose and/or methyl galactoside import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Putative ribose/galactose/methyl galactoside import ATP-binding protein 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Carbohydrate importer 2 (CUT2) (TC 3.A.1.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: B2MG_ORNAN
Sequence: MGSRWGIAVLGLFCFVSCLEAITSSPKIQVYSRHPAQIGESNNLNCYVSSFHPPQISIRLLKNGQEMPGVEMSDLSFSNDWTFHRLVHTVFTPSNQDTFECEVVHEGVKKTVKWEPDN
What is the function of this protein?
Component of the class I major histocompatibility complex (MHC).  Involved in the presentation of peptide antigens to the immune system (By similarity).
What are the official names of this protein?
Beta-2-microglobulin.
What is the protein family that this protein belongs to?
Belongs to the beta-2-microglobulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: EVGS_ECO57
Sequence: MKFLPYIFLLCCGLWSTISFADEDYIEYRGISSNNRVTLDPLRLSNKELRWLASKKNLVIAVHKSQTATLLHTDSQQRVRGINADYLNLLKRALNIKLTLREYADHQKAMDALEEGEVDIVLSHLVASPPLNDDIAATKPLIITFPALVTTLHDSMRPLTSSKPVNIARVANYPPDEVIHQSFPKATIISFTNLYQALASVSAGQNDYFIGSNIITSSMISRYFTHSLNVVKYYNSPRQYNFFLTRKESVILNEVLNRFVDALTNEVRYEVSQNWLDTGNLAFLNKPLELTEHEKQWIKQHPDLKVLENPYSPPYSMTDENGSVRGVMGDILNIITLQTGLNFSPITVSHNIHAGTQLNPGGWDILPGAIYSEDRENNVLFAEAFITTPYVFVMQKAPDSEQTLKKGMKVAIPYYYELHSQLKEMYPEVEWIKVDNASAAFHKVKEGELDALVATQLNSRYMIDHYYPNELYHFLIPGVPNASLSFAFPRGEPELKDIINKALNAIPPSEVLRLTEKWIKMPNVTIDTWDLYSEQFYIVTTLSVLLVGSSLLWGFYLLRSVRRRKVIQGDLENQISFRKALSDSLPNPTYVVNWQGNVISHNSAFEHYFTADYYKNAMLPLENSESPFKDVFSNTHEVTAETKENRTIYTQVFEIDNGIEKRCINHWHTLCNLPASEHAVYICGWQDITETRDLIHALEVERNKAINATVAKSQFLATMSHEIRTPISSIMGFLELLSGSGLSKEQRVEAISLAYATGQSLLGLIGEILDVDKIESGNYQLQPQWVDIPTLVQNTCHSFGAIAASKSIALSCSSTFPDHYLVKIDPQAFKQVLSNLLSNALKFTTEGAVKITTSLVHIDDNHAVIKMTIMDSGSGLSQEEQQQLFKRYSQTSAGRQQTGSGLGLMICKELIKNMQGDLSLESHPGIGTTFTITIPVEIIQQVAAVEAKAEQPITLPEKLSILIADDHPTNRLLLKRQLNLLGYDVDEATDGVQALHKVSMQHYDLLITDVNMPNVDGFELTRKLREQNSSLPIWGLTANAQANEREKGLNCGMNLCLFKPLTLDVLKTHLSQLHQVAHIVPQYRHLDIEALKNNTANDLQLMQEILMTFQHETHKDLPAAFHALEAGDNRTFHQCIHRIHGAANILNLQKLINISHQLEITPVSDDSKPEILQLLNSVKEHIAELDQEIAVFCQQNN
What is the function of this protein?
Member of the two-component regulatory system EvgS/EvgA.  Phosphorylates EvgA via a four-step phosphorelay in response to environmental signals (By similarity).
What are the official names of this protein?
Sensor protein EvgS.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RTCB_PYRHO
Sequence: MVVPLKRIDKIRWEIPKFDKRMRVPGRVYADEVLLEKMKNDRTLEQATNVAMLPGIYKYSIVMPDGHQGYGFPIGGVAAFDVKEGVISPGGIGYDINCLAPGTRVLTEHGYWLKIEEMPEKFKLQRLRVYNIEEGHNDFSKVVFVAEREVGSEEKAIRIVTESGKVIEGSEDHPVLTPEGYVYLRNVKEGDYILVYPFEGVPYEEKKGVILDESAFEGEDPQVVKFLRERNLIPLQWKDPKVGILARILGFALANGYISENDNLTFHGKEEVLREVRKDLEELGIEAIVAEEDKLKVTSREFAFLLEKLGMAHDSIPEWIIEGPLWIKRNFLAGLFGANGSIVEFKGDVPLPITLTHSRELLNDVSRILEGFKVRAKIKMGKNGSYQLVIEDEDSIRNFLGRINYEYDPEKKARGLIAYAYLKFKELMKGNLMTFEEFARDRGYEGGFVAEKVIEVKSVKPEYDKFYDIGVYHSAHNFIANGIVVHNCGVRLIRTNLTEKEVRPRIKQLVDTLFKNVPSGVGSQGRIKLHWTQIDDVLVDGAKWAVDNGYGWERDLERLEEGGRMEGADPEAVSQRAKQRGAPQLGSLGSGNHFLEVQVVDKIFDPEVAKAYGLFEGQVVVMVHTGSRGLGHQVASDYLRIMERAIRKYRIPWPDRELVSVPFQSEEGQRYFSAMKAAANFAWANRQMITHWVRESFQEVFKQDPEGDLGMDIVYDVAHNIGKVEEHEVDGKRVKVIVHRKGATRAFPPGHEAVPRLYRDVGQPVLIPGSMGTASYILAGTEGAMKETFGSTCHGAGRVLSRKAATRQYRGDRIRQELLNRGIYVRAASMRVVAEEAPGAYKNVDNVVKVVSEAGIAKLVARMRPIGVAKG
What is the function of this protein?
Essential for tRNA splicing and maturation (Probable).  Acts by directly joining spliced tRNA halves to mature-sized tRNAs (PubMed:22320833, PubMed:22949672).  Joins RNA with 2',3'-cyclic-phosphate or 3'-phosphate ends to RNA with 5'-hydroxy ends (PubMed:22320833, PubMed:22949672).
What are the official names of this protein?
tRNA-splicing ligase RtcB, 3'-phosphate/5'-hydroxy nucleic acid ligase, tRNA ligase RtcB.
What is the protein family that this protein belongs to?
Belongs to the RtcB family.
Protein: LV403_HUMAN
Sequence: MAWVSFYLLPFIFSTGLCALPVLTQPPSASALLGASIKLTCTLSSEHSTYTIEWYQQRPGRSPQYIMKVKSDGSHSKGDGIPDRFMGSSSGADRYLTFSNLQSDDEAEYHCGESHTIDGQVG
What is the function of this protein?
V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
What are the official names of this protein?
Immunoglobulin lambda variable 4-3.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: RNPA_ACIBS
Sequence: MMALYSFSTDLRIRCAADYKSVFDDALFKVHQPHFLFLAKLTEQPNSRLGIVVAKKKVRRAHERNRIKRLARESFRLHQPKFGSDIDVVVMPKVGIETITNAELYQQLDFAWQKLQRLAKKHSKVVPTSQN
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: MDH_SULDN
Sequence: MNQGKRVGIIGAGNVGATVAYSLAMLGSCHEIILRDNKIDVAKGKALDMSQAAAAVRSHTIVSVAEEMADLTNCDVVVVTAGSPRLPGMSRDDLLMINANITKDVIAGVAKYSPDAIIIMVSNPLDAMTYVALKESGFDRSRVIGMAGILDSARMASFIQEKLGYGGGQIRASVMGGHGDDMVPLARYSTVAGVPLTDLMSTSEINEIVIRTRNGGAEIVGHLKTGSAYYAPAKATALMVEAILKDTKQIHPCAVFLEGEYGHSDVVSGVPVMLGANGAEKIIEISLDESEKIMFEGSCNSVRTLIDTLNKNKFFDKGE
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: PIP_NEIMA
Sequence: MYEIKQPFHSGYLQVSEIHQIYWEESGNPDGVPVIFLHGGPGAGASPECRGFFNPDVFRIVIIDQRGCGRSRPYACAEDNTTWDLVADIEKVREMLGIGKWLVFGGSWGSTLSLAYAQTHPERVKGLVLRGIFLCRPSETVWLNEAGGVSRIYPEQWQKFVAPIAENRRNQLIEAYHGLLFHQDEEVCLSAAKAWADWESYLIRFEPEEVDEDAYASLAIARLENHYFVNGGWLQGDRAILNNIGKIQHIPTIIVQGRYDLCTPMQSAWALSKAFPEAELRVVQAGHRAFDPPLVDALVQAVEDILPHLL
What is the function of this protein?
Specifically catalyzes the removal of N-terminal proline residues from peptides.
What are the official names of this protein?
Proline iminopeptidase, PIP, Prolyl aminopeptidase, PAP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOXO_CAEEL
Sequence: MQLEQKSSLHCSKCRNFLQKFSQDMQAWNCRELDSPLPSDITLHNLEPARPDSGMSFSTDFDDDFFNLDLHQQERSASFGGVTQYSQQFLREKCSFSPYFHTSLETVDSGRTSLYGSNEQCGQLGGASSNGSTAMLHTPDGSNSHQTSFPSDFRMSESPDDTVSGKKTTTRRNAWGNMSYAELITTAIMASPEKRLTLAQVYEWMVQNVPYFRDKGDSNSSAGWKNSIRHNLSLHSRFMRIQNEGAGKSSWWVINPDAKPGRNPRRTRERSNTIETTTKAQLEKSRRGAKKRIKERALMGSLHSTLNGNSIAGSIQTISHDLYDDDSMQGAFDNVPSSFRPRTQSNLSIPGSSSRVSPAIGSDIYDDLEFPSWVGESVPAIPSDIVDRTDQMRIDATTHIGGVQIKQESKPIKTEPIAPPPSYHELNSVRGSCAQNPLLRNPIVPSTNFKPMPLPGAYGNYQNGGITPINWLSTSNSSPLPGIQSCGIVAAQHTVASSSALPIDLENLTLPDQPLMDTMDVDALIRHELSQAGGQHIHFDL
What is the function of this protein?
Functions in the Insulin/IGF-1-like signaling (IIS) mediated pathway (PubMed:24834345).  Transcript level in the early adult may play a role in lifespan modulation, but effect is more significant than that played by isoform a (PubMed:24834345).
What are the official names of this protein?
Forkhead box protein O, FOXO, Abnormal dauer formation protein 16.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between cytoplasm and nucleus (PubMed:11381260, PubMed:17894411). Nuclear translocation is inhibited by phosphorylation by AKT proteins (PubMed:11381260, PubMed:11747825, PubMed:21531333). Association with ftt-2 sequesters daf-16 in the cytoplasm (PubMed:21531333). Association with prmt-1 allows for translocation to the nucleus (PubMed:21531333). Nuclear translocation is promoted by phosphorylation by unc-43 and inhibited by dephosphorylation by tax-6 (PubMed:23805378). Nuclear translocation is promoted by jnk-1 upon heat stress and by sek-1 upon oxidative stress (PubMed:15888317, PubMed:15767565). Nucleocytoplasmic shuttling is induced by starvation, heat treatment, hypergravity, reactive oxygen species (generated by juglone), exposure to tributyltin or 4-hydroxy-E- globularinin (4-HEG) and the flavonoids kaempferol and fisetin (PubMed:11381260, PubMed:17551714, PubMed:18832074, PubMed:19252938, PubMed:21531333, PubMed:23805378). Nuclear localization induced by nematophagous fungal infection (PubMed:24146615). SUBCELLULAR LOCATION: [Isoform a]: Nucleus. Cytoplasm. Note=Ratio of nuclear to cytoplasmic localization is daf-2-dependent. SUBCELLULAR LOCATION: [Isoform d]: Nucleus. Cytoplasm. Note=Ratio of nuclear to cytoplasmic localization is daf-2-dependent. SUBCELLULAR LOCATION: [Isoform f]: Nucleus. Cytoplasm. Note=Ratio of nuclear to cytoplasmic localization is daf-2-dependent.
Protein: ARR10_ARATH
Sequence: MTMEQEIEVLDQFPVGMRVLAVDDDQTCLRILQTLLQRCQYHVTTTNQAQTALELLRENKNKFDLVISDVDMPDMDGFKLLELVGLEMDLPVIMLSAHSDPKYVMKGVKHGACDYLLKPVRIEELKNIWQHVVRKSKLKKNKSNVSNGSGNCDKANRKRKEQYEEEEEEERGNDNDDPTAQKKPRVLWTHELHNKFLAAVDHLGVERAVPKKILDLMNVDKLTRENVASHLQKFRVALKKVSDDAIQQANRAAIDSHFMQMNSQKGLGGFYHHHRGIPVGSGQFHGGTTMMRHYSSNRNLGRLNSLGAGMFQPVSSSFPRNHNDGGNILQGLPLEELQINNNINRAFPSFTSQQNSPMVAPSNLLLLEGNPQSSSLPSNPGFSPHFEISKRLEHWSNAALSTNIPQSDVHSKPDTLEWNAFCDSASPLVNPNLDTNPASLCRNTGFGSTNAAQTDFFYPLQMNQQPANNSGPVTEAQLFRSSNPNEGLLMGQQKLQSGLMASDAGSLDDIVNSLMTQEQSQSDFSEGDWDLDGLAHSEHAYEKLHFPFSLSA
What is the function of this protein?
Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3'.  Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system.  Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes.  Could directly activate some type-A response regulators in response to cytokinins.
What are the official names of this protein?
Two-component response regulator ARR10, Receiver-like protein 4.
What is the protein family that this protein belongs to?
Belongs to the ARR family. Type-B subfamily.
Protein: NLTP1_PRUPE
Sequence: ITCGQVSSALAPCIPYVRGGGAVPPACCNGIRNVNNLARTTPDRQAACNCLKQLSASVPGVNPNNAAALPGKCGVHIPYKISASTNCATVK
What is the function of this protein?
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes.  May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.
What are the official names of this protein?
Non-specific lipid-transfer protein 1, LTP 1, Allergen Pru p 1, Major allergen Pru p 3.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
Protein: KBTB2_HSPV
Sequence: MDIKNDIRNISNLLDDDILCDVIITIGDGEEIKAHKTILAAGSTYFKTMFTTPMIARDLVTRVNLQMFDKDVVKNIVQYLYNRHISSMNVIDVLKCADYLLINDLVTNCESYIKDYINHDIYHKLYEMVHIPIVKYIKRMLISNIPTLITTNAFKKTVFEILFDIISTNDSVYLYREGYKVTILLKWLEYNYITEEQLLCILSCIDIQNLDKKSRLLLYSNKTINMHPSCIQFLLDNKQNRNIIPHQLCLACHDTNYNVCNPCIVVYNINTMEYSVISTIPNHIINYASAIVDNDIIIARGYNFNNPSLNKVYKINIENKIHVELPPIIKNRCRFSLAVIDDTIYAIGGQNGTNVERTIECYTMGDDKWKMLPNMPIALSSYGMCVLDQYIYIIGGRTQHIDYTSVHTVNSIDMEEDTNISNKVMRYDTVNNIWETLPNFWTGTINPGVVSHKDDIYVVCDIKDEKNVKTCIFRYNTNTYNGWELVTTTESRLSALHTILYNNTIMMLHCYESYMLQDTFNVYTREWNHMCHQHSNSYIMYNILPIY
What is the function of this protein?
Probable substrate-specific adapter of CUL3-containing E3 ubiquitin-protein ligases which mediate the ubiquitination and subsequent proteasomal degradation of host target proteins.
What are the official names of this protein?
Kelch repeat and BTB domain-containing protein 2.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: COPZ3_ARATH
Sequence: MAGTNDSCPLVKNILLLDSEGKRVAVKYYSDDWATNASKLAFEKYVFSKTSKTNARTEAEITLLESNIVVYKFAQDLHFFVTGGENENELVLSSVLQGFFDAVALLLRNNVEKMEALENLDLIFLCLDEMVDQGMVLETDANVIAGKVAMQSAEASGSLSEQTLTQALATAREHLARSLLT
What is the function of this protein?
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.  Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).  The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex (By similarity).
What are the official names of this protein?
Coatomer subunit zeta-3, Zeta-3-coat protein, Zeta-COP 3.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes small subunit family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.
Protein: PSIE_SHISS
Sequence: MTSLSRPRVEFISTILQTVLNLGLLCLGLILVVFLGKETVHLADVLFAPEQTSKYELVEGLVVYFLYFEFIALIVKYFQSGFHFPLRYFVYIGITAIVRLIIVDHKSPLDVLIYSAAILLLVITLWLCNSKRLKRE
What are the official names of this protein?
Protein PsiE.
What is the protein family that this protein belongs to?
Belongs to the PsiE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DAPE_BURL3
Sequence: MSATLALTEQLIARASVTPDDQHCQQIMTERLTALGFECETIASHGVTNLWAVKRGTDGRDGKLLAFAGHTDVVPTGPLEQWSSPPFIPAHRDGKLYGRGAADMKTSLAAFVVASEEFVAAHPGHRGTIAFLITSDEEGPATDGTVKVVELLEARGERMDYCIVGEPTSTTELGDVVKNGRRGSMSGELVVKGVQGHIAYPHLAKNPIHLLAPALAELAAEQWDEGNEYFPPTTWQVSNLHAGTGASNVIPGHADLLFNFRFSTASTVEGLQARVHAILDKHGLEYTLKWSVSGLPFLTPRGELSGALENAIRTETGITTELSTTGGTSDGRFIARICPQVIEFGPPNGSIHKIDEHIEVRFVDPLKNVYRRVLEQLIA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: PTGCB_BUCBP
Sequence: MFKNAFSNLQKIGRSLMLPVSVLPIAGILLGIGSANFKIIPHTISNIMTEAGSSVFSNMPLIFAIGIALGFTKNDGVSALAAVVSYGIMTKTLSITIPIFSNLSDINVNQKYLLDTGILGGIIAGSISAYIFNTFYRIQLPEYLGFFAGRRFVPIASGLISIIFGCILSIIWPPIGNVIKTFSEWAAYQNPTLAFGIYGTVERALVPFGLHHIWNVPFQMQIGEYNNSIGQIFHGDIARYMAGDSTAGKLSGGFIFKMYGLPFAALAMWHCANKKNKAKIGGIMMSGALTAILTGITEPIEFSFILVAPILYVIHAILAGLAFPICILLNMRSGTSFSHGLIDFIVLSGNSNNFWLFPIVGLFYGILYYGIFYFMIKKFNLKTPGREKSITYINQKTIKETALLVISILGGKTNIINLDACITRLRITVLDISKVNQKKLKNLGASGVIVSGSGIQIVFGTQSDHIKTEIDNYMSNTNQ
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II complex composed of PtsG and Crr is involved in glucose transport.
What are the official names of this protein?
PTS system glucose-specific EIICB component, EIICB-Glc, EII-Glc.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SPP2B_CHICK
Sequence: MAARWAQFLLFSLLSLPQVYCEYGMVHVLSEKGSSKGKDYCILFNSQWAHLPHDLGKASLLQLQDQTASVLCSPSDVPDGGFNNRIPMVMRGNCTFYEKVRLAQINGARGLLIVSRERLVPPGGNRSQYEEIDIPVALLSYSDMLDIVKSFGRSVKGAMYAPNEPVLDYNMVIIFVMAVGTVAIGGYWAGSRDVKERYMKHKRDDGAEKHEDETVDVTPIMICVFVVMCCSMLVLLYFFYDHLVYVIIGIFCLAASIGLYSCLSPFVRRFPLGKCRIPDNNLPYFHKRPQVRILLLAVFCISVSVVWGVFRNEDQWAWVLQDALGIAFCLYMLKTIRLPTFKGCTLLLLVLFVYDVFFVFITPFLTKTGESIMVEVAAGPSDSATHEKLPMVLKVPRLNSSPLALCDRPFSLLGFGDILVPGLLVAYCHRFDIQVQSSRVYFVACTIAYGIGLLVTFVALALMQMGQPALLYLVPCTLITSFSVALWRKELAMFWTGSGFAKDLPQPPLVIASVNCPQLPKDSNVPASQQETEEMANPTLHVKELHSPTLAAEEPADNDTKTEQSEVSIAQSEEAAGHNKDDLESKSLNLEQKQLE
What is the function of this protein?
Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane.
What are the official names of this protein?
Signal peptide peptidase-like 2B, SPP-like 2B, SPPL2b.
What is the protein family that this protein belongs to?
Belongs to the peptidase A22B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein; Lumenal side.
Protein: ERG6_NEUCR
Sequence: MPSTIALEKEDHQRDAEFKKVMHGDSAKAAGGVAALLKKNTEAQQIAVDEYFKHFDNKTAEAETQADREARTKEYATLTRHYYNLATDIYEYGWGQCFHFCRYSPGESFYQAIARHEHYLAAQIGIKKDMKVLDVGCGVGGPAREIAKFTDAHITGLNNNDYQIDRATHYAVRDGLSGQLKFVKGDFMQMSFPDNSFDAVYAIEATVHAPKLEGVYGEIYRVLKPGGTFGVYEWLMTDNYDNDNVEHRDIRLAIEVGNGISNMVTISEGLAAMKNVGFELVHHEDLADRNDPMPWYWPIAGELRYMQSYLDFFTVVRMTHTARRILHGFAGILETVGLAPKGTKKTADALARGADGLVAGAKKKLFTPMYLMVGKKPLN
What is the function of this protein?
Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of lanosterol to form eburicol.
What are the official names of this protein?
Sterol 24-C-methyltransferase erg-4, Delta(24)-sterol C-methyltransferase, S-adenosyl-L-methionine:sterol C-24 methyl transferasee, SAM:SMT.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family.
Protein: LIVB5_BRUA2
Sequence: MIGTRLPAWTRVLACGVAGLSLMTISAKAEDVITLGASVQLSGPVANTGRYYQDAYNITIDKINAAGGVKVDGKPYKLALKIYDNQSNVNLSVRQYTQLVTTDKVNFLLGPFASNFALADSVISEKYRIPMVQGGGASDEIYSRNFKYIFGTLAPASNYFGSTVEMLKGLDPKVTNVALVYADDSFDVSVADGTRKLLKDAGFTIAADEKFATNSTDFTSLISQIKSKNVDAVLVAGHETEVLNFVRQSKSLAFDPKLYSFTVGVPTEDFRKALGKDANYAFGMTAWLPSADLKDRWFGDAAKFETEYKARFNYEPDYHAASGASDVEAFAEAIEKANSLDPQKVRDALASIKFDSLYGPIAFDKQGQINLPQIVVQVQDGKLVEIRGPAGQVNPPQYPMPAWNAR
What is the function of this protein?
Component of an amino-acid transport system.
What are the official names of this protein?
Leu/Ile/Val-binding protein homolog 5.
What is the protein family that this protein belongs to?
Belongs to the leucine-binding protein family.