PharMolix/UniProtQA huggingface dataset:
Protein: MURA_MYCLE
Sequence: MAERFVVTGGNRLSGEVTVGGAKNSVLKLMAATLLAEGTSTITNCPDILDVPLMAEVLRGLGATVELYGDVARITSPDEPKYDADFAAVRQFRASVCVLGPLVGRCKQARVALPGGDAIGSRPLDMHQAGLRQLGARCNIEHGCVVASAETLRGAEIQLEFPSVGATENILMAAVVAEGVTTIHNAAREPDVVDLCTMLNQMGAQVEGVGSPTMTITGVPRLYPTEHRVIGDRIVAATWGIAAAMTRGDIAVTGVDPAHLQLVLHKLHDAGATVTQTDDSFRVAQYERPKAVNVATLPFPGFPTDLQPMAIALTSIADGTSMITENVFEARFRFVEEMIRLGADARTDGHHAVVRGLPQLSSAPVWCSDIRAGAGLVLAGLVADGDTEVYDVFHIDRGYPLFVENLANLGAEIERVCL
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_BARHE
Sequence: MSKHIAGPEIERLIQLLARIPGLGPRSARRAALHLIKKKETLLEPLGAAIQAAVQKVCICSVCGNVDTIDPCSICTDPRRDDATIIVVEDIADLWALERAKTLAARYHVLGGKLSPLDGIGPDELNIAPLIQRVVQNPITEIILAVNATVEGQTTAHYITDQLSNFSVKVTRLAHGVPVGGELDYLDDGTLAAALQARTNL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: LEG1_BOVIN
Sequence: MACGLVASNLNLKPGECLRVRGEVAADAKSFLLNLGKDDNNLCLHFNPRFNAHGDVNTIVCNSKDAGAWGAEQRESAFPFQPGSVVEVCISFNQTDLTIKLPDGYEFKFPNRLNLEAINYLSAGGDFKIKCVAFE
What is the function of this protein?
Lectin that binds beta-galactoside and a wide array of complex carbohydrates (PubMed:1900835, PubMed:8108426, PubMed:7773775).  Plays a role in regulating apoptosis, cell proliferation and cell differentiation.  Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase.  Strong inducer of T-cell apoptosis.
What are the official names of this protein?
Galectin-1, Gal-1, 14 kDa lectin, Beta-galactoside-binding lectin L-14-I, Galaptin, Lactose-binding lectin 1, Lectin galactoside-binding soluble 1, S-Lac lectin 1.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Cytoplasm. Secreted. Note=Can be secreted; the secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion.
Protein: IDI_PECAS
Sequence: MPLTEVVLVDENDKPTGVMEKQEAHVKGELHRAITVYIFNSRQQLLLQQRAEEKYHSGGLWSNTCCSHPAPGEETLQAAHRRLYEEMGLRCALTPMFTLTYRLQLDNGLIEHELGHVYFGVTDDVPQINPDEVSSYEYQSIDEITQRMMMTPEQFTAWFQLTFARIPDYWQAFKSEQSR
What is the function of this protein?
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate Delta-isomerase, IPP isomerase, IPP:DMAPP isomerase, Isopentenyl pyrophosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_MALP2
Sequence: MFGSKFKICKIEAYEVIDSRGFPTVAAKVYAKNGVFAKAMVPSGASTGEREAVELRDGDKERFNGKGVLKAVNNVNTIIAPKVVGMDCRQQTKIDELMISLDGTPNKAKLGANAILAVSLAVAKLAAMIEEKPLYKYIRQNIMGDSSDSWTMPVPMLNVINGGAHADNTIDFQEFMFMPVGAKSLKEAVRMASECFHSLQSILKSKKLDTNKGDEGGFAPNLKNADEALKLMVEAVEKAGYKPGVDADVAFALDPATSELFDADKKTYTFEKALKAKILTAKDAVKKSEDMVKYWDGLCKKYPIISIEDGLAENDWDGFQLMVKDLGSRVQIVGDDLFCTNPKIVKEGISKGVANSVLIKVNQIGTLTETIETIKAAHAAGWTCVVSHRSGETEDTTIADIAVGLSTGQIKTGSMSRSERIAKYNRLIEIENELGSKAHYPGKSTFKSIK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RBL_SPIMR
Sequence: SVGFKAGVKEYKLTYYTPEYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVPGEEDQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPVAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCTEALFKAQVETGEIKGHYLNATAGTCEEMMKRAVFARELGVPIIMHDYLTGGFTANTTLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKGLRMSGGDHIHAGTVVGKLEGERDITLGFVDLLRDDFIEKDRSRGIYFTQDWVSLPGVIPVASGGIHVXHMPALTEIFGDDSVLQXGGGTLXXPWGNAPXAVANRVALX
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site (By similarity).
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: AMZ2_MOUSE
Sequence: MQVLRHSEHTLKTALLSKNPVLVSQYEKLDAGEQRLMNEAFQPRSNLFEPITVHSQSDWISSHPEAPQDFEQFFSDRYRKAPCPKKHIIYIQSIGSLGNTRVISEEYIKWLKGYCEAFFYGLKVKFLEPVSVSETKCSFRVNEHTQNLQIHTGHILAFLKKNKPEDAFCIVGITMIDLYPRDSWNFVFGQASLSSGVGIFSFARYGKDFYTSKYEGNVTSLQLTSPTDYSIFDNYYIPEITSVLLLRSCKTLTHEIGHILGLRHCQWLACLMQGSNHLEESDRRPLNVCPICLRKLQSAIGFNIVERYRALVKWIDDESCNESGATPKSSSEHAHLPKPVEAFKDWREWLMRCIALLEK
What is the function of this protein?
Probable zinc metalloprotease.
What are the official names of this protein?
Archaemetzincin-2, Archeobacterial metalloproteinase-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M54 family.
Protein: FMT_ACIB3
Sequence: MKIIFAGTPEFAATALAALLKTSHEIIAVYTQPDRKAGRGQKLTPSPVKQLALEHNIPVYQPLHFKASTEEGLAAQQELAALGADVMVVAAYGLILPQAVLDTPKYGCLNIHGSLLPRWRGAAPIQRAIATGDDETGITIMQMAAGLDTGDMMYKTYCPITSEDTSATLHDKLAAQGATAICAVLESEETLQKYLAEREVQDESLTVYAHKLVKSEARIDWSMNAVQVDRNIRAFNPWPVAFIQLDENNALRVWNSTISSQSKVNAQAGEIIAIDKQGVHVACGENTFICLTSVQWPGGKALNAQQIAQTQKLHVGQILP
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: DNAA_XANOM
Sequence: MDAWPRCLERLEAEFPPEDVHTWLKPLQAEDRGDSIVLYAPNAFIVDQVRERYLPRIRELLAYFAGNGEVALAVGSRPRAPEPAPAPVAATIAPQAAPIAPFAGNLDSHYTFANFVEGRSNQLGLAAAIQAAQKPGDRAHNPLLLYGSTGLGKTHLMFAAGNALRQAKPAAKVMYLRSEQFFSAMIRALQDKAMDQFKRQFQQIDALLIDDIQFFAGKDRTQEEFFHTFNALFDGRQQIILTCDRYPREVEGLEPRLKSRLAWGLSVAIDPPDFETRAAIVLAKARERGAEIPDDVAFLIAKKMRSNVRDLEGALNTLVARANFTGRSITVEFAQETLRDLLRAQQQAIGIPNIQKTVADYYGLQMKDLLSKRRTRSLARPRQVAMALAKELTEHSLPEIGDAFAGRDHTTVLHACRQIRTLMEADGKLREDWEKLIRKLSE
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXS_SALHS
Sequence: MSFDIAKYPTLALVDSTQELRLLPKESLPKLCDELRRYLLDSVSRSSGHFASGLGTVELTVALHYVYNTPFDQLIWDVGHQAYPHKILTGRRDKIGTIRQKGGLHPFPWRGESEYDVLSVGHSSTSISAGIGIAVAAEKEGKDRRTVCVIGDGAITAGMAFEAMNHAGDIRPDMLVILNDNEMSISENVGALNNHLAQLLSGKLYSSLREGGKKVFSGVPPIKELLKRTEEHIKGMVVPGTLFEELGFNYIGPVDGHDVMGLISTLKNMRDLKGPQFLHIMTKKGRGYEPAEKDPITFHAVPKFDPSSGCLPKSSGGLPGYSKIFGDWLCETAAKDSKLMAITPAMREGSGMVEFSRKFPDRYFDVAIAEQHAVTFAAGLAIGGYKPVVAIYSTFLQRAYDQVIHDVAIQKLPVMFAIDRAGIVGADGQTHQGAFDLSYLRCIPDMVIMTPSDENECRQMLLTGYHYNDGPTAVRYPRGNAQGVALTPLEKLPIGKGLVKRHGEKLAILNFGTLMPEAAKVAEALNATLVDMRFVKPLDDTLILEMAAQHDALVTLEENAIMGGAGSGVNEVLMAHRKPVPVLNIGLPDFFIPQGTQEEARAELGLDAAGIEAKIKAWLA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: PURQ_LISMC
Sequence: MKFAVIQFPGSNCDLDMLHAIRDSLGEEAEYVWHAETSLAGFDAVLLPGGFSYGDYLRTGAIAKFSSIMPEVLRFAEMGKPVLGVCNGFQILTEIGLLPGALIRNNNLHFICKTVPLRVANASTMFTGLYKEGEIIQVPVAHGEGNYYCDDETLLKLKDNNQIVFTYDSVNPNGSRADIAGIVNERGNVLGMMPHPERAVEEIIGGTDGLRLFESVVKAWKEEQVNA
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTH_YERPS
Sequence: MSSIKLIVGLANPGAEYAQTRHNAGAWYVDLLAERHNQSLKEESKFFGYTARLNLAGQDIRLLVPATFMNLSGKAVAAMASFYRILPEEILVAHDELDILPGMAKLKLGGGNGGHNGLKDIQNKLGNNPNFYRLRIGIGHPGDKSKVTGFVLGKPPASEQTLIDDAIDESIRCTEVLLNEGMTKAMNRLHAFKASA
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAPA3_MYCTO
Sequence: MLRVGPLTIGTLDDWAPSTGSTVSWRPSAVAHTKASQAPISDVPVSYMQAQHIRGYCEQKAKGLDYSRLMVVSCQQPGQCDIRAANYVINAHLRRHDTYRSWFQYNGNGQIIRRTIQDPADIEFVPVHHGELTLPQIREIVQNTPDPLQWGCFRFGIVQGCDHFTFFASVDHVHVDAMIVGVTLMEFHLMYAALVGGHAPLELPPAGSYDDFCRRQHTFSSTLTVESPQVRAWTKFAEGTNGSFPDFPLPLGDPSKPSDADIVTVMMLDEEQTAQFESVCTAAGARFIGGVLACCGLAEHELTGTTTYYGLTPRDTRRTPADAMTQGWFTGLIPITVPIAGSAFGDAARAAQTSFDSGVKLAEVPYDRVVELSSTLTMPRPNFPVVNFLDAGAAPLSVLLTAELTGTNIGVYSDGRYSYQLSIYVIRVEQGTAVAVMFPDNPIARESVARYLATLKSVFQRVAESGQQQNVA
What is the function of this protein?
Involved in the biosynthesis of polyacyltrehalose (PAT), a pentaacylated, trehalose-based glycolipid that could have a role in anchoring the bacterial capsule.  Catalyzes the sequential transfer of two palmitoyl groups onto a single glucose residue of trehalose generating the diacylated product 2,3-diacyltrehalose (trehalose dipalmitate).
What are the official names of this protein?
Acyltransferase PapA3, Long-chain-acyl-CoA--trehalose acyltransferase, Mycolipenoyl-CoA--2-(long-chain-fatty acyl)-trehalose mycolipenoyltransferase, Polyketide synthase-associated protein A3.
What is the protein family that this protein belongs to?
Belongs to the PapA acyltransferase family.
Protein: RL4_THEVB
Sequence: MVACVVKDWQGADSGEATLDLATAKPETASHIVHRALVRQLANARQGTVSTKTRAEVRGGGRKPWRQKGTGRARAGSIRSPLWRGGGVIFGPKPRDYSQKMNRKERRLALRTALMSRVEDLIVVQDFADHLPRPKTKELVTALQRWGIEPEQKVLLLAADITETVALSARNVPTLKLLRADQLNVFDLLYADRIVATTGAIAKIQEVYGD
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: PUNA_CELSP
Sequence: TTTTPPSTPPLDDPATDPFLVARAAADHIAQATGVEGHDMALVLGSGWGGAAELLGEVVAEVPTHEIPGFSAPAVAGHLSVTRSIRVERADGSVRHALVLGSRTHLYEGKGVRAVVHGVRTAAATGAETLILTNGCGGLNQEWGAGTPVLLSDHINLTARSPLEGPTFVDLTDVYSPRLRELAHRVDPTLPEGVYAQFPGPHYETPAEVRMAGILGADLVGMSTTLEAIAARHCGLEVLGVSLVTNLAAGISPTPLSHAEVIEAGQAAGPRISALLADIAKR
What is the function of this protein?
The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.  Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.
What are the official names of this protein?
Purine nucleoside phosphorylase, PNP, Pu-NPase, Inosine phosphorylase, Inosine-guanosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the PNP/MTAP phosphorylase family.
Protein: RL24_JANSC
Sequence: MAAKLKKGDKVVVLTGKDKGKQGEISSVNPSAGKAIVDGVNIAIRHTKQSQSNQGGRIPQPMPIQLSNLALLDANGKATRVGFKIEDGKKVRVAKTTGDVI
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: RL24_CLOD6
Sequence: MRVKKGDTVVVIAGKDKGKKGSVLKVYPKTSKVLVEGVNVITKHQKPSAMNQQGGIINKEAPIHISNVMPFDPETGKGVRVRYEVKDGNKVRVSAKSGKEL
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: THA11_BOVIN
Sequence: MPGFTCCVPGCYNNSHRDKALHFYTFPKDAELRRLWLKNVSRAGVSGCFSTFQPTTGHRLCSVHFQGGRKTYTVRVPTIFPLRGVNERKVARRPAGAAAARRRQQQQQQQQQQQQQQQQQQPSPSASTAQTTQLQPNLVSASAAVLLTLQAAVDSSQAPGTVPPVPTTPTGEDVKPIDLTVQVEFAAAEGAAAAAAASELEAATAGLEAAECPMGPQLVVVGEEGFPDTGSDHSYSLSSGTTEEELLRKLNEQRDILALMEVKMKEMKGSIRHLRLTEAKLREELREKDRLLAMAVIRKKHGM
What is the function of this protein?
Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells.  Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers (By similarity).
What are the official names of this protein?
THAP domain-containing protein 11.
What is the protein family that this protein belongs to?
Belongs to the THAP11 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=May be regulated by shuttling of the protein between the cytoplasm and nucleus.
Protein: LIPA_PSYCK
Sequence: MTNAVQTHTPAARAKPKKAIQGEKLRGYDKVARIPIKIIPTVEAKKKPDWIRVKLSSPAEVARIKSTLREQKLYTVCEEAACPNLPQCFADGTATFMIMGDICTRRCPFCDVGHGRPNELDKDEPRHTAETIQGLGLKYAVITSVDRDDLKDGGAMHFVEVLNESRALSPNCLIEILVPDFRGRMDIALDLLTETAPDVFNHNIETVPRLYKAFRPGSDYQHSLDLLKIYKERRPDIATKCGFMVGLGETEEEIYKLLDDLKAHNVDMITVGQYLQPSKDHAPVDRYVHPDEFQRYMDYGKKIGFFNIWAGPMVRSSYFADRQYYGEDCPAPIRSKKALAAEGKLGC
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPS_EHRCR
Sequence: MILGIGTDIVYVPRISNLWKKFGTKFLKRVFSEKEIEDSKKYTNFDAQVRHFAKRFAAKEAYVKAVGTGFGKSIKMPDIIVSNNLHGKPQITINNSNIKYKIELSISDEKDYAIAFVVLYTEL
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPS26_DROME
Sequence: MNFLGFGQSADIEIVFDGAEHKTAEVKGEDGKVEKMLLFYDGETVSGKVNVTLKKPGSKLEHQGIKIEFIGQIELYYDRGNHHEFKCLAKALARPGDLIQNNSYPFDFPKVEKQFEVYAGSNVRLRYFLRATIVRRISDITKEVDIAVHTLCSYPEMNNPIKMEVGIEDCLHIEFEYNKSKYHLRDTIIGKIYFLLVRIKIKHMEIAIIKKESTGTGPTMFNENETIAKYEIMDGAPVKGESIPIRVFLAGYNLTPTMRDINKKFSVKYFLNLVLMDTEDRRYFKQQEITLWRKADKPRYHGAQQHQQQQHQHVPLHAPPHLVSGPAAPTVAHSLISSSTDSGEVGGAPTAPGTAGSESKMGLFTRESPNQEFSQQQMDSPPLTPTPSTASVAVAVPTAASSVSEPAPERGIGDGAAAATTSASPVAMLSSSPPPLLPVSPLSRSETEASEQVQPEDEDLDAITPNTKKTGATPLATD
What is the function of this protein?
Component of the retromer complex which acts in conjunction with wingless (wg) and clathrin-mediated endocytosis to sustain a wntless (wls) traffic loop.  This loop encompasses the Golgi, the cell surface, an endocytic compartment and a retrograde route leading back to the Golgi, thereby enabling wls to direct wg secretion.  The hh and dpp signaling pathways do not require the retromer complex suggesting that it does not play a general role in exocytosis.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 26, VPS26 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the VPS26 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: RPOA_VITVI
Sequence: MVREKVTVSTRTLQWKCVESRVDNKRLCYGRFILSPLIKGQADTIGIAMRRALLGEIEGTCITRAKSEKIPHEYSTIVGIQESVHEILMNLKEIVLRSNLYGTRGAFICARGPGYVTAQDIISPPSVEIVDNTQHIARLMEPIDLCIGLQIERNRGYSIKRPNNFQDGSYPIDAVFMPVRNANHSIHSYGNGNERQEILFLEIWTNGSLTPKEALHEASRNLIDLFIPFLHAEEETLHLEYNQHKSTLPPLTFHDRLAKLRKNKKEIELKYIFIDQLELPPRIYNCLKRSNIHTLLDLLNKSQKDLMKIEDFRIEDVKQLLGILEKHFTID
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y438_STRPG
Sequence: MTAILITGYRSFEIGIFDHKDPRVSIIKQAIRKDLIGYLENGVDWFIFTGNLGFEQWALEVANELKEEYPLQIATIFLFETHGDKWNEKNQEVLSQFKAVDFVKYYFPNYEQPTQFSQYYQFLLEKTEGAYVFYDTENETNLKYFLKKAKDMPHYQLLLLTFDRLNDMSQS
What are the official names of this protein?
UPF0398 protein SpyM50438.
What is the protein family that this protein belongs to?
Belongs to the UPF0398 family.
Protein: ATP5E_BOVIN
Sequence: MVAYWRQAGLSYIRYSQICAKAVRDALKTEFKANAMKTSGSTIKIVKVKKE
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element.  Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
What are the official names of this protein?
ATP synthase subunit epsilon, mitochondrial, ATPase subunit epsilon, ATP synthase F1 subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ATPase epsilon family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane.
Protein: SYP_POLNS
Sequence: MKASQSFLATLKEAPSDAEVVSHKLMVRAGLIRKLSAGVYNYLPLGLKVIRKVENIIREEMNRAGAIELLMPMIQPAELWQETGRWEKMGPELLRIKDRHDRDFLIQPTSEEVVTDLARNEIKSYKQLPVNFYQIQTKFRDERRPRFGIMRGREFSMKDAYSFDRDTEGLKKSYQIMFDAYTRIFKRMGLQFRAVTADNGAIGGSGSQEFHVIADTGEDAIVYCPDSDYAANLEAAESLALIASRAAASVAMAKVPTPDKTNCADVAKFLNIPIESTVKSLLFVADQENGPAKLFMLLVRGDHELNEVKASKIPGMAESRFASEAEIKLACNAPAGYLGPVGVSADATVVADRTVANMADFVCGANDAGHHLTGVNWGRDLPEPLVLDIRNAVVGDPSPDGKGVVDICRGIEVGHVFQLGTRYSEAMGCTYLDQQGKAQPMVMGCYGIGVTRLLGAAIEQGHDEKGIIWPISMAPCEVVICPMGYEKSEAVKAACDQLHDGLLAAGVDVILDDRNERPGAMFADWGLIGAPFRVVIGDRGLVDSQVEFKGRTDAESQNIPLTQIKEKVIAAIQTTKQSIV
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DF191_ARATH
Sequence: MAKSVNATGFITYMVIFLILTGISRVKAKKPPCLEGRTAYVSPGPCSNSLCTQDCRPAGYHTGKCKVEWSTPICKCYGCRKV
What are the official names of this protein?
Putative defensin-like protein 191.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: PPNP_PSESM
Sequence: MFKVNEYFDGTVKSIAFSQAEGQATIGVMAAGEYEFGTAQREIMHVISGELNVKLPDSTDWETFSTGSQFNVPANSKFQLKVSVDTAYLCEYR
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: Y4760_STRCO
Sequence: MRRGRSRPAGAAPAALLLPLLLLLPLTGCDRLAAAPAEHAAAAGDPAQDADRGRRLPPVVDHVRTDDPVVFLTYDDGAERDPAFVGLIRERRLPVTLFLTDTVAGPAYGDLARLRPFGASLQNHTLDHRSLRGLPHAGQRAEICGQQTKLRSRFGVRAHLFRPPHGTYDTTTLRAAADCGITALVLWRATLDADGALTYTRGDHRLHPGDIVAVDPDHPTAANLAARTERLLETIEEQGLRVGNLENYL
What are the official names of this protein?
Uncharacterized protein SCO4760.