PharMolix/UniProtQA huggingface dataset:
Protein: NSP4_ROTHV
Sequence: MDKLADLNYTLSVITSMNDTLHSIIEDPGMAYFPYIASVLTVLFALHKASIPTMKIALKTSKCSYKVIKYCIVTIINTLLKLVGYKEQVTTKDEIEQQMDRIVKEMRRQLEMIDKLTTREIEQVELLKRIHDNLITRPVDVIDMSKEFNQKNIKTLDEWESRKNPYEPSEVTASM
What is the function of this protein?
The secreted form acts as an enterotoxin that causes phospholipase C-dependent elevation of the intracellular calcium concentration in host intestinal mucosa cells.  Increased concentration of intracellular calcium disrupts the cytoskeleton and the tight junctions, raising the paracellular permeability.  Potentiates chloride ion secretion through a calcium ion-dependent signaling pathway, inducing age-dependent diarrhea.  To perform this enterotoxigenic role in vivo, NSP4 is released from infected enterocytes in a soluble form capable of diffusing within the intestinal lumen and interacting with host plasma membrane receptors on neighboring epithelial cells such as integrins ITGA1/ITGB1 and ITGA2/ITGB1.
What are the official names of this protein?
Non-structural glycoprotein 4, NSP4, NCVP5, NS28.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP4 family.
What are the subcellular locations of this protein?
Host rough endoplasmic reticulum membrane; Single-pass type III membrane protein. Host membrane, host caveola; Single-pass type III membrane protein. Secreted. Note=NSP4 localizes also in vesicular structures which contain autophagosomal markers and associate with viroplasms in virus- infected cells. Additionally, a soluble form of glycosylated NSP4 is secreted despite retention of its transmembrane domain.
Protein: RIMM_PSEA7
Sequence: MPTPADDLVVIGKIVSVYGIRGEVKVYSFTDPLDNLLDYRRWTLRRDGETRQAELVRGRLHGKVLAAKLKGLDDREEARTFTGYEICIPRSELPSLEEGEYYWYQLEGLKVIDQGGQLLGVIDHLLETGANDVMVVKPCAGSLDDRERLLPYTGQCVLSIDLAAGEMRVDWDADF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPB_MYCGI
Sequence: MSSVEGMAQSIRSGTEPVRVQWLGRIDYQAAWDLQRELAEERIAGGPDSLLLLEHPEVYTAGRRTLAHERPVDGTPVIDTDRGGKITWHGPGQLVGYPIIGLAEPLDVVNFVRRLEESLISVCASFGVQTGRVEGRSGVWVAGDGGRPDRKIAAIGIRVARATTLHGFAINCDCDLGAFGSIVPCGIADAGVTSLTAELGRTVGVAEVIDRVSEAVLDALDGRIALGVASSPGVDSAQ
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CM3J_CONMA
Sequence: QKCCSGGSCPLYFRDRLICPCC
What is the function of this protein?
Probable competitive antagonist of fish muscle acetylcholine receptor.  Inhibits postsynaptic nicotinic acetylcholine receptors (nAChRs) from fish (zebrafish and goldfish) and frogs (IC(50)=0. 1 uM).  Protects these receptors from block by alpha-bungarotoxin and alpha-conotoxin EI.  Does not block nAChRs at the neuromuscular junction of Rana pipiens.  Shows a weak inhibition on mammalian adult and fetal muscle nAChRs (alpha-1-beta-1-delta-epsilon/CHRNA1-CHRNB1-CHRND-CHRNE and alpha-1 beta-1 gamma delta/CHRNA1-CHRNB1-CHRNG-CHRND) (IC(50)=3-45 uM).  In vivo, induces paralysis in goldfish (Carassius auratus) but not mice.
What are the official names of this protein?
Conotoxin MIIIJ, AlphaM-MIIIJ.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: FMT_JANMA
Sequence: MKIIFAGTPEFAAVALAALHAAGFEIPLVLTQPDRPAGRGMQLHASAVKQFALAHDIPVAQPVSLRLDGKYPEVAAEAHALLKATPHDVMVVAAYGLILPQSILDIPPRGCINIHASLLPRWRGAAPIHRAIESGDAETGVTIMQMELGLDTGPMLAMQRLPITADDTTASLHDKLATLGGEMIVQTLRRMEQGDLPAEPQPDGANYAAKILKEEATLDFTQPAEQLARKIRAFNPFPGAAATCDGTLIKFWHAQAVPASNQLPPGQVIAANPHDGVLVACGDGALRVTELQKPGGKRLSAVEFLKGFTLEDKRFQ
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: CYB_ALLVD
Sequence: MSAEKTENLSWIDKRFPLSETWRNHLSEYYAPKNLNFWSFFGSLAILTLVIQIVTGVWLAMSYKPDAGLAFASVEYIMRDVDWGWLIRYMHSTGASMFFIVIYLHMFRGLLWGSYRKPRELLWMIGVVIYLVMMATAFFGYLLPWGQMSYWGAQVIVNLFAAVPVVGEDLSVWVRGDFVISDATLNRFFAFHFLLPFLLAGLVFLHIVALHHVGSNNPDGIEIKEGPKGNRWSDKAPADGIPFHPYYTVKDLMGVVVFLAIFGYVMFFNPTMGGLFLEAPNFQPANPMQTPAHIAPVWYFTPFYAMLRAVPPMYGSQFPGVVVMFAAILILFVLPWLDRSPVKSMRYKGPIFKWATGIFVVSFVALAWLGIQPASDFYTLLSQIFTVLYFAYFLLMPIYSSLDKTKPVPERVTS
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
What are the official names of this protein?
Cytochrome b.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DPH3_EMENI
Sequence: MADEALSIYDEIEIEDMTFDANLQIYHYPCPCGDRFEIAIDDLRYGEDIAVCPSCSLMIKVIFDQSDLPKEEKKETEGVSVKA
What is the function of this protein?
Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2.  Dph1 and dph2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising dph3 and a NADH-dependent reductase, predominantly cbr1.  Acts as an electron donor to reduce the Fe-S cluster in dph1-dph2 keeping the [4Fe-4S] clusters in the active and reduced state.  Restores iron to dph1-dph2 iron-sulfur clusters which have degraded from [4Fe-4S] to [3Fe-4S] by donating an iron atom to reform [4Fe-4S] clusters, in a manner dependent on the presence of elongation factor 2 and SAM.  Associates with the elongator complex and is required for tRNA Wobble base modifications mediated by the elongator complex.  The elongator complex is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s 2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine).
What are the official names of this protein?
Diphthamide biosynthesis protein 3.
What is the protein family that this protein belongs to?
Belongs to the DPH3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GPAT4_HUMAN
Sequence: MFLLLPFDSLIVNLLGISLTVLFTLLLVFIIVPAIFGVSFGIRKLYMKSLLKIFAWATLRMERGAKEKNHQLYKPYTNGIIAKDPTSLEEEIKEIRRSGSSKALDNTPEFELSDIFYFCRKGMETIMDDEVTKRFSAEELESWNLLSRTNYNFQYISLRLTVLWGLGVLIRYCFLLPLRIALAFTGISLLVVGTTVVGYLPNGRFKEFMSKHVHLMCYRICVRALTAIITYHDRENRPRNGGICVANHTSPIDVIILASDGYYAMVGQVHGGLMGVIQRAMVKACPHVWFERSEVKDRHLVAKRLTEHVQDKSKLPILIFPEGTCINNTSVMMFKKGSFEIGATVYPVAIKYDPQFGDAFWNSSKYGMVTYLLRMMTSWAIVCSVWYLPPMTREADEDAVQFANRVKSAIARQGGLVDLLWDGGLKREKVKDTFKEEQQKLYSKMIVGNHKDRSRS
What is the function of this protein?
Converts glycerol-3-phosphate to 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) by incorporating an acyl moiety at the sn-1 position of the glycerol backbone (PubMed:18238778).  Active against both saturated and unsaturated long-chain fatty acyl-CoAs (PubMed:18238778).  Protects cells against lipotoxicity (PubMed:30846318).
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase 4, 1-acylglycerol-3-phosphate O-acyltransferase 6, 1-AGP acyltransferase 6, 1-AGPAT 6, Acyl-CoA:glycerol-3-phosphate acyltransferase 4, Lysophosphatidic acid acyltransferase zeta, LPAAT-zeta, Testis spermatogenesis apoptosis-related protein 7, TSARG7.
What is the protein family that this protein belongs to?
Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: IAA20_ARATH
Sequence: MGRGRSSSSSSIESSSKSNPFGASSSTRNLSTDLRLGLSFGTSSGTQYFNGGYGYSVAAPAVEDAEYVAAVEEEEENECNSVGSFYVKVNMEGVPIGRKIDLMSLNGYRDLIRTLDFMFNASILWAEEEDMCNEKSHVLTYADKEGDWMMVGDVPWEMFLSTVRRLKISRANYHY
What is the function of this protein?
Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations.  Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin-responsive promoter element (AuxRE).  Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression.
What are the official names of this protein?
Auxin-responsive protein IAA20, Indoleacetic acid-induced protein 20.
What is the protein family that this protein belongs to?
Belongs to the Aux/IAA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL14_BRUMB
Sequence: MIQMQTNLDVADNSGARRVMCIKVLGGSKRRYASVGDIIVVSIKEAIPRGRVKKGDVMKAVVVRTAKDIRRPDGSVIRFDNNAAVLIDNKKEPIGTRIFGPVPRELRAKNHMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: PRRP_RAT
Sequence: MALKTWLLCLLLLSLVLPGASSRAHQHSMETRTPDINPAWYTGRGIRPVGRFGRRRATPRDVTGLGQLSCLPLDGRTKFSQRG
What is the function of this protein?
Stimulates prolactin (PRL) release and regulates the expression of prolactin through its receptor GPR10.  May stimulate lactotrophs directly to secrete PRL.
What are the official names of this protein?
Prolactin-releasing peptide, PrRP, Prolactin-releasing hormone.
What are the subcellular locations of this protein?
Secreted.
Protein: SOMA_HUMAN
Sequence: MATGSRTSLLLAFGLLCLPWLQEGSAFPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFEEAYIPKEQKYSFLQNPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFLRSVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF
What is the function of this protein?
Plays an important role in growth control.  Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1.  It stimulates both the differentiation and proliferation of myoblasts.  It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
What are the official names of this protein?
Somatotropin, Growth hormone, GH, GH-N, Growth hormone 1, Pituitary growth hormone.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: YIHY_ECO8A
Sequence: MLKTIQDKARHRTRPLWAWLKLLWQRIDEDNMTTLAGNLAYVSLLSLVPLVAVVFALFAAFPMFSDVSIQLRHFIFANFLPATGDVIQRYIEQFVANSNKMTAVGACGLIVTALLLMYSIDSALNTIWRSKRARPKIYSFAVYWMILTLGPLLAGASLAISSYLLSLRWASDLNTVIDNVLRIFPLLLSWISFWLLYSIVPTIRVPNRDAIVGAFVAALLFEAGKKGFALYITMFPSYQLIYGVLAVIPILFVWVYWTWCIVLLGAEITVTLGEYRKLKQAAEQEEDDEP
What are the official names of this protein?
UPF0761 membrane protein YihY.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ACP_PSESM
Sequence: MSTIEERVKKIVAEQLGVKSEEVVNTASFVEDLGADSLDTVELVMALEEEFETEIPDEEAEKITTVQAAIDYVNSHQA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2172_SYMTH
Sequence: MLDILRDNPLLLLFIVAGIGYPLGRVRIGGIHLGVAAVLFVGLAFGALDPSLKLPEIVYQFGLALFVYCVGLSSGHGFLRSFRGKGVIYNLLTLGVILLAAALLLIPHYLLSLRPGETAGVFAGLLTSTPALAAAVEYLTRAGAAGQLSDPVVGYSIAYPASVLGVILAIYLAERCFRIDYRAEARTLKDVPGVSPEITCWTLRVCRPKAFGRTVRDLVAEHRLQVVFGRIRRGDHADVVSWETHLEEGDLVTAVGPVEELERAAQVIGCVSEVQADLDRSEVDMREVFVSNPEVAGRTLRELNLPNRFGAVVSRVWRGDLQLLPYADMPLELGDRVRVLSRRERQQEVAAYLGDSYRAISEIDIAVLGLGMALGIGLGLVPIPLPGGITVRLGLAGGPLIVALFLGARQRTGSLVWVLPYSANMLLRQMGLTIFLAAVGTRSGYEFAQMLTQPRGWAILGASAAIIVLLSWVMLYVGYRWLRIPMGLLTGMVAGMQTQSATLGFALDQAGNDLPTVGYAMVYPMAMVVKIVLAPVIIAVLT
What are the official names of this protein?
Uncharacterized transporter STH2172.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPC2_HUMAN
Sequence: MDVLAEEFGNLTPEQLAAPIPTVEEKWRLLPAFLKVKGLVKQHIDSFNYFINVEIKKIMKANEKVTSDADPMWYLKYLNIYVGLPDVEESFNVTRPVSPHECRLRDMTYSAPITVDIEYTRGSQRIIRNALPIGRMPIMLRSSNCVLTGKTPAEFAKLNECPLDPGGYFIVKGVEKVILIQEQLSKNRIIVEADRKGAVGASVTSSTHEKKSRTNMAVKQGRFYLRHNTLSEDIPIVIIFKAMGVESDQEIVQMIGTEEHVMAAFGPSLEECQKAQIFTQMQALKYIGNKVRRQRMWGGGPKKTKIEEARELLASTILTHVPVKEFNFRAKCIYTAVMVRRVILAQGDNKVDDRDYYGNKRLELAGQLLSLLFEDLFKKFNSEMKKIADQVIPKQRAAQFDVVKHMRQDQITNGMVNAISTGNWSLKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTRKVSGPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTDMEDGPIVKLASNLGVEDVNLLCGEELSYPNVFLVFLNGNILGVIRDHKKLVNTFRLMRRAGYINEFVSISTNLTDRCVYISSDGGRLCRPYIIVKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKDTTHLEIEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQKPMVKTKTIELIEFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKCTLKRYTNQTFDKVMGPMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVTQIPLEGSNVPQQPQYKDVPITYKGATDSYIEKVMISSNAEDAFLIKMLLRQTRRPEIGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGVLDGRFHYGTAFGGSKVKDVCEDLVRHGYNYLGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLMISSDAFEVDVCGQCGLLGYSGWCHYCKSSCHVSSLRIPYACKLLFQELQSMNIIPRLKLSKYNE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Second largest core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.  Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit.  Pol III is composed of mobile elements and RPC2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft (By similarity).  Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses.  Acts as nuclear and cytosolic DNA sensor involved in innate immune response.  Can sense non-self dsDNA that serves as template for transcription into dsRNA.  The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway.
What are the official names of this protein?
DNA-directed RNA polymerase III subunit RPC2, RNA polymerase III subunit C2, C128, DNA-directed RNA polymerase III 127.6 kDa polypeptide, DNA-directed RNA polymerase III subunit B.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLGA_SYNS9
Sequence: MRILFAAAECAPMIKVGGMGDVVGSLPPALAKLGHDVRLIMPGYSQLWSKLQIPDEPIWRAQTMGTEFAVYEAKHPTNGMTIYLVGHPVFDPERIYGGEDEDWRFTFFASAAAEFSWNVWKPQVLHCHDWHTGMIPVWMHQDPEISTVFTIHNLKYQGPWRWKLDRITWCPWYMQGDHTMAAALINADRVNAVSPTYAQEIRTAEYGENLHGLLNFVSGKLRGILNGIDLEAWDPATDKALPANYSAADLTGKAVCKQVLQERMGLEVRDDAFLLGMVTRLVDQKGVDLLLQVADRLLSYTDSQIVVLGTGDRGLESGLWQLASRYPGKCAVFLTYDDDLSRLIYAGSDAFLMPSRFEPCGISQLYAMRYGSVPVVRNVGGLVDTVPPHDPNADRGTGFCFDRFEPVDFYTALVRAWEAYRHRSSWQDLQKRGMTEDYSWDRSAVEYDLMYKDVCGIKEPTPDAALLEQFSRGQDADPSRADQIDVEPSSSSSAPMTPPGRNPLNRLFGRRSG
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: TIG_PELPD
Sequence: MQVNVETISPVSKKVSIEIPADQVNSEIEKTYATIQKRAKIQGFRPGKAPLQLIKRTYADSMRDEVMRRFYETTLFKTLAEHKIEPIDAPTVECDILEEGTPFKYSALVEVMPEVLLTQYTGLEITKERYVFDPQKIEDEIARMRDGMAQLVPVEGDVAVEMGHMVTIDYAFSVDGFPEESTSAENAVVEVGAHRLLPEFEDQLVGMKCGESKHVTVTLPEAYRNPEVAGKEGAFMVTLNEIKRKELPELNDEFAQQFGEFETVEQLREKMTEYHQQHEQDRIEQEQRETVIQALIEKNPLDVPQSMVKRQVEQMLQNLKNRLKSRNMSMEMMGMDDDSFRERVRDSATDKVRGGLLLMALIEKEDFSVSDEEIEKRYEKLAGGNEEMLERIKEHYTSSPSVRHSLIAEIKEDKAVRFLLDNAVITETDPAETAAEA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: OTC_RHILO
Sequence: MSVRHFTDLSTVSEGDLRFMLDDAVVRKARLKAGERTRPLEGKVLAMIFDKPSTRTRVSFDVGMRQLGGETIMLTGTEMQLGRSETIADTAKVLSRYVDAIMIRTTSHDRLLELTENATVPVINGLTDDTHPCQLMADIMTFEEHRGPVAGKTIAWTGDGNNVLHSLLEASARFRFNLNVAVPEGSEPAQKHIDWSKAHGGKLHFTRSPEEAVDQADCVVTDCWVSMGQEHRARGHNVFSPYQVNAKLMAHAKPDALFMHCLPAHRGEEVTDEVIDGPHSVVFDEAENRLHAQKAVLAWCLGA
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_ECO24
Sequence: MNLNATILGQAIAFVLFVLFCMKYVWPPLMAAIEKRQKEIADGLASAERAHKDLDLAKASATDQLKKAKAEAQVIIEQANKRRSQILDEAKAEAEQERTKIVAQAQAEIEAERKRAREELRKQVAILAVAGAEKIIERSVDEAANSDIVDKLVAEL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PCKA_STAAE
Sequence: MSVDTYTETTKIDKLLKKPTSHFQLSTTQLYNKILDNNEGVLTELGAVNASTGKYTGRSPKDKFFVSEPSYRDNIDWGEINQPIDEETFLKLYHKVLDYLDKKDELYVFKGYAGSDKDTMLKLTVINELAWHNLFAKNMFIRPESKEEATKIKPNFTIVSAPHFKADPEVDGTKSETFVIISFKHKVILIGGTEYAGEMKKGIFSVMNYLLPMQDIMSMHCSANVGEKGDVALFFGLSGTGKTTLSADPHRKLIGDDEHGWNKNGVFNIEGGCYAKAINLSKEKEPQIFDAIKYGAILENTVVAEDGSVDFEDNRYTENTRAAYPINHIDNIVVPSKAAHPNTIIFLTADAFGVIPPISKLNKDQAMYHFLSGFTSKLAGTERGVTEPEPSFSTCFGAPFFPLHPTVYADLLGELIDLHDVDVYLVNTGWTGGKYGVGRRISLHYTRQMVNQAISGKLKNAEYTKDSTFGLSIPVEIEDVPKTILNPINAWSDKEKYKAQAEDLIQRFEKNFEKFGEKVEHIAEKGSFNK
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_CERS1
Sequence: MPSLKDLKNRIGSVKNTRKITKAMQMVAAAKLRRAQEAAEAARPFAERMTAVMTGLAGSVGSSESAPRLLAGTGSDKVHLLVVMTAERGLCGGFNSSIVRLARAHAAKLLTQGKTVKILTVGKKGREQLRRDLGQHFIGHVDLSEVKRMGYPVAQGIARDLLDRFDKGEFDVATIFFARFQSVISQVPTAQQVIPAVFEGEGEVSSLYDYEPSEEGVLADLLPRGVATQIFTALLENGASEQGARMSAMDNATRNAGDMINRLTIEYNRSRQAAITKELIEIISGAEAL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MTOX_YERPS
Sequence: MDYDLIVIGSGSVGSAAGYYASQAGLNVLMIDSAMPPHQAGSHHGETRIMRHAYGEGEKYVPLVLRAQALWDQLAAQTGEKLFQACGVINLGPDNSTFLQNVQRSAQQYDLPVETLNSTQIREKWPVFTVPDNYIAVFEPQSGYLRSELAVKTLIKAVTEAGCGILFNCPVTAIESHQAGVDVVTIDGTYSATKVVVTAGTWVKELLPTLPVTPVRKVFSWHQADGRYSEANHFPAFTVEMPDNILYYGFPAQNDALKLGKHHGGQLIESAAQRKPFGRYAEDGTEVFSFLRHFLPGVGVCLRGEACSYDMSPDEDFIIDTLPEDERVMVVSGLSGHGFKFATALGEVAALFAQDKPSPIDISAFSLARFR
What is the function of this protein?
Catalyzes the oxidative demethylation of N-methyl-L-tryptophan.
What are the official names of this protein?
N-methyl-L-tryptophan oxidase, MTOX.
What is the protein family that this protein belongs to?
Belongs to the MSOX/MTOX family. MTOX subfamily.
Protein: IF4H_BOVIN
Sequence: MADFDTYDDRAYSSFGGGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDAIFKDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAEGRKQDKGGFGFRKGGPDDRGFRDDFLGGRGGSRPGDRRTGPPMGSRFRDGPPLRGPNMDFREPTEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARPREEVVHKEQE
What is the function of this protein?
Stimulates the RNA helicase activity of EIF4A in the translation initiation complex.  Binds weakly mRNA (By similarity).
What are the official names of this protein?
Eukaryotic translation initiation factor 4H, eIF-4H.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region.
Protein: GATC_NEIG2
Sequence: MALTLADVDKIARLSRLQLTAEEKEKSLQELNDIFTMVEQMQNINTDGIEPMAHPHEVALRLREDEVTETDRAAEYQAVAPEVRNRLYIVPQVIEE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.