PharMolix/UniProtQA huggingface dataset:
Protein: RHCG_BOVIN
Sequence: MIWNTNLRWRLPVACLLLEVALIALFGVFVRYDMDADPHWVQEKVIKNLSTDLENEFYYRYPSFQDVHVMIFVGFGFLMTFLQRYGYSSVGFNFLLAAFGIQWALLMQGWLQSFDGRYILVDLENLINADFCVGSVCVAFGAVLGKVSPVQLLIMTLFQVTLFSINEYILLNLLEVKDSGGSMTIHAFGAYFGLTVAWILYRPNLHLSKERQSSTYHSDLFAMIGTLFLWMYWPSFNSAISNHGDAQHRAAINTYCSLAACVLTSVALSSALHRKGKLDMVHIQNATLAGGVGLGTVAELMVLPFGSLIIGFVCGIVSTLGFVYLTPFLESRLHIQDTCGVHNLHGIPGIIGGIAGAVTASIANIDLYGEEGLAYAFGIERSKLNWSPNMQGRFQAAGLFVSLAMALVGGVIVGVILRLPFWGQAPDENCFEDAVYWEIPKEPKSTALRSEDSSIKPPEP
What is the function of this protein?
Ammonium transporter involved in the maintenance of acid-base homeostasis.  Transports ammonium and its related derivative methylammonium across the plasma membrane of epithelial cells likely contributing to renal transepithelial ammonia transport and ammonia metabolism.  Postulated to primarily mediate an electroneutral bidirectional transport of NH3 ammonia species according to a mechanism that implies interaction of an NH4(+) ion with acidic residues of the pore entry followed by dissociation of NH4(+) into NH3 and H(+).  As a result NH3 transits through the central pore and is protonated on the extracellular side reforming NH4(+) (By similarity).  May act as a CO2 channel providing for renal acid secretion (By similarity).
What are the official names of this protein?
Ammonium transporter Rh type C, Rhesus blood group family type C glycoprotein, Rh family type C glycoprotein, Rh type C glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Note=Also detected at the basolateral membrane and in subapical vesicles.
Protein: LIS1_PICST
Sequence: MNRSQILTDRQQQELNKAILQYLEPMLTESSSDQEVYRSLQQILVPPSSSSSEAIVDNYLEKKWSTVLRLQRKIIDLENEVGTLRSIVDGQQSVSNGAASVISKDRINWLPNRASKSFPTQQNQLVMASVIHPVLPVIFGGCSDGSIIVWNIVNDDTSIPEKIIRAHTRSINKLAFSVEPADLSKDLTKSKTYIFASCSADLSIKIWDSSSYRHIRTLTGHDHTVSSVAFSQSNPDHLYSVSRDKTVKIWDLVNGYCVKSFTGHSEWVRDIDVASVNSQLSLNNMKVSAELGDFVVTCSNDQSVRVSHAESGAGLALLIGHTHVIEKVKFLPAVSNTILDKFLKENHAQFPSIPQELVSDEIFTTTLGYKYCISGGRDNLLKLWLIPPPTLIPHRSPLPAQHNNSQGWAIADLVGHQSWVKAIAIHPNGRFIFSGSDDKTIKVWDLANLNVTGSVKCVRTLSGHDGFINDLDFAAFNRDSGKEDKIKEDATEEESHQQLMKFIEGRMRCLFISGAADNSIKLWS
What is the function of this protein?
Positively regulates the activity of the minus-end directed microtubule motor protein dynein.  Plays a central role in positioning the mitotic spindle at the bud neck during cell division.  Targets cytoplasmic dynein to microtubule plus ends, thereby promoting dynein-mediated microtubule sliding along the bud cortex and consequently the movement of the mitotic spindle to the bud neck.
What are the official names of this protein?
Nuclear distribution protein PAC1, Lissencephaly-1 homolog, LIS-1, nudF homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LIS1/nudF family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes to the plus ends of microtubules and the mitotic spindle poles.
Protein: MTDH_PETCR
Sequence: ILSPFKFSRRATGDNDVRFKVLYCGVCHSDLHMVKNEWGMTTYPIVPGHEIVGRVTEVGSKVEKFKVGDAVGVGCLVGSCLSCENCDDDSENNCAKQVQTYAFTNVDGSITYGGYADSMVADQHFVLRWPENLPLDSGAPLLCAGITTYSPLRYHGLDKPGTKVGVVGLGGLGHVAVKMAKAFGAHVTVISTSESKKQEALEKLGADEFLVSSDSDQMQAATGTLHGIIDTVSALHPVVPLLGLLKVNGKLVMVGAPEKPLELPVFPLLMGRKVLAGSNIGGLKETQEMLDFAAQHNITADVEVIPVDYVNTAMERLVKSDVRYRFVIDVANTIKTE
What is the function of this protein?
Oxidizes mannitol to mannose.  Provides the initial step by which translocated mannitol is committed to central metabolism and, by regulating mannitol pool size, is important in regulating salt tolerance at the cellular level (By similarity).
What are the official names of this protein?
Mannitol dehydrogenase, NAD-dependent mannitol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: TILS_LACPL
Sequence: MTPIQKFNRQLAAAKLLSPQQTVVVAVSTGVDSMVLLHLLQRLPAAERPRVVVAHVNHHLREQSQMEADYLRQYCQQQNLKLVMADWLPAAHPKSGIEAAGRQFRYHVFAKVMRENRATAVLTAHHANDQVETYLMKLARGGDISQLTGIATSRPFATGRLIRPLLTWSKDQLRNYAAEQHVVYFEDVTNQDVALTRNRIRHRVVPELMTVNPQLLKHVADYQQQLTTLLTAKKQMVTVLLSQVVTATGALVVDQWGALPSQWQLAVFATWLEQQTQQLFTESKLQPLVSWGQRTRPATSRLTVNAAWELYRNAGIIEALPIKKRGKKLMPREKIMVDLNQWQKITATQTVGIFTRVPNVVSQPFWLTEADWPLVWRPWQAGDRIVLKGGGHQLVRRLLIDRKVPAERREQVQVLVNAQGNVLWVVGHKFSYRTTGTQTVFLALKHES
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA56B_DAMDA
Sequence: YQTSSPGSNITIGPL
What are the official names of this protein?
Pregnancy-associated glycoprotein 56B, FdPAG56B.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: SYS_CHLPM
Sequence: MLDITLLRDSPDEIVTMLHNRQQPEDEPKLRQLLEEDAERRKLVQESDELKSLRNRKSKEIAEIKKSGSGSADALILEMQSVGTAIAEMDSRLTALETSMEDILLALPNRLHPSVPVGRSAEENEVFGEPVSFTHPLDFSLKNHLELGKSLGILDFERGAKVSGAGFPVYVGKGARLERALINFMLDSHTEKHGYKEVFPPFMVNRESLRGTGQWPKFAGEVYHAPEDELYLIPTAEVPVTNLHRGELLETESLPISYAAYSACFRREAGSYGKETRGFLRVHQFNKVEMVKFTKPEDSYQALEDIRGHAEAILRALEIPYRVLLLCSGDISANAAKCYDIEVWSPAEEKYLEASSCSNFEDYQARRANIRFRRDGKSKPEFVHTLNGSGLATSRLMVSLMEHYQTPEGGILVPEVLKPYTGFSEITPSA
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI_DESHD
Sequence: MVIITSWKRFKEYLYYDQELELLLDISRMNFSAEFLTELAEPMRDAYHQLQLLEKGALANPDEGRMVGHYWLRNPDLAPTEEIAQDIKETLKEILDFAEQIHSGRLQGEKGNPFRNILLVGVGGSILGPRFVADALASSRDKMKAFFIDNGDPDGIDRVLSRIGEELPATLCLIISKSGGTIETRNGMLEVRRAYEEAGLSFPDHAVAITQRGSQLDKLSQKEGWLRAFPMWDWVGGRTSLLSAVGLLSLALQGIDVAGLLQGAKDCDGRTRRPDTLANPGALLALMWYYSTQGQGGKQMVVLPYKDRLELFTKYLQQLIMESLGKEKNLQGETVHQGITVYGNKGSSDQHSYLQQLLEGPDNFFVTFIEVLKDRQGSSAYMEENSTSGEYLQAFLLGTREALTQKGRESLTITVKEVNAYTIGVLIALFERAVSIYALLVGINAYHQPAVEMGKKAAGQAIQLKNNIVECLKKHPDKRFSVHEIALAIGEEAHQEMVFKLLLHLTTNPEHGVNMAAGHPLPESRFFVSGPIL
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHEB_NEOTN
Sequence: MLDAFSRVVVNSDAKAAYVGGSDLQALKKFIADGNKRLDSVNAIVSNASCIVSDAVSGMICENPGLIAPGGNCYTNRRMAACLRDGEIILRYVSYALLAGDPSVLEDRCLNGLKETYIALGVPTNSSVRAVSIMKAAAVAFITNTASQRKMATADGDCSALASEVASYCDRVAAAIS
What is the function of this protein?
Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex.
What are the official names of this protein?
R-phycoerythrin beta chain.
What is the protein family that this protein belongs to?
Belongs to the phycobiliprotein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side. Note=Forms the periphery of the phycobilisome rod.
Protein: RL4_SYNC1
Sequence: MAKIAVYDINRNQVSERELSDEVFNAEVKEYLIHDMVRYQLAARRQGTSAAKNRSAVAGGGKKPYRQKGTGNARQGTIRAPHFVGGGAAFGPSPRDFSFKLNRKVKKAALRSALSARFKEERVAVLNDFQLEKIGTKAVVEVLNRFELSNVLVVVGEDNRNLELSARNLPHVKVLKAEGVNVYDLMNHRNLVVTEGAVEQLEGALG
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: ALY2_ARATH
Sequence: MAPVRKSRSVNKRFTNETSPRKDAGKSKKNKLRKKLSDKLGPQWTRLELERFYDAYRKHGQEWRRVAAAIRNSRSVDMVEALFNMNRAYLSLPEGTASVAGLIAMMTDHYSVMEGSGSEGEGHDASEVPRKQQKRKRAKPQRSDSPEEVDIQQSIGSPDGCLTFLKQARANGTQRHATGKRTPRVPVQTSFMRDDREGSTPPNKRARKQFDANDDVAHFLALALTDASRRGGSPKVSESPNRRTELSDSSPIKSWGKMSRTRKSQSKHCGSSIFEEWMESSRERKLDSDKDTTLLMDMERAGEMEAPRKGKRVYKKRVKVEEAECNDSDDNGEACSATQGLRSKSQRRKAAIEASREKYSPRSPKKRDDKHTSGAFDALQALAELSASMLPANLMESELSAQLKEERTEYDMDEKSSTPEATSTSSHGEKANVEPDDSLLHAISSVENANKRKSKPSRLVSTDCDDVPTGKLQPQTSGSLRKRKPKVLGDEAPAEFSQNKSINKKELPQDENNMKSLVKTKRAGQVPAQSKQMKTVKALEESAITSDKKRPGMDIVASPKQVSDSGPTSLSQKPPNRRKKSLQKSLQEKAKSSETTHKAARSSRSLSEQELLLKDKLATSLSFPFARRRCIFEWFYSAIDHPWFSKMEFVDYLNHVGLGHIPRLTRLEWSVIKSSLGRPRRFSERFLHEEREKLKQYRESVRKHYTELRTGAREGLPTDLARPLAVGNRVIAIHPKTREIHDGKILTVDHNKCNVLFDDLGVELVMDIDCMPLNPLEYMPEGLRRQIDKCLSMKKEAQLSGNTNLGVSVLFPPCGLENVSFSMNPPLNQGDMIAPILHGKVSSNTSSPRQTNHSYITTYNKAKEAEIQRAQALQHALDEKEMEPEMLEIVKGSKTRAQAMVDAAIKAASSVKEGEDVNTMIQEALELVGKNQLLRSSMVKHHEHVNGSIEHHHNPSPSNGSEPVANNDLNSQDGSEKNAQMPSELITSCVATWLMIQMCTERQYPPADVAQLIDAAVTSLQPRCPQNLPIYREIQTCMGRIKTQIMSLVPT
What are the official names of this protein?
Protein ALWAYS EARLY 2, AtALY2.
What are the subcellular locations of this protein?
Nucleus.
Protein: TWF2A_XENLA
Sequence: MAHQTGIHATPELKEFFAKARNGSIRLIKVVIEEEQLVLGSHKELKHAWEQDYDALIVPLLDESQPCYILYRLDSQNAQGYEWIFLSWSPDHSPVRLKMLYAATRATVKKEFGGGHIKDEIFGTLKEDVALSGYKKHVSLCAAPAPLTAAERELQEIKINEVKTEISVESKQQTLQGLSFPLRPEAEEAILLLKQKKINYIQLRLDLEKETVDLVHTKHTEIKDLPGRIPQDTARYHFFLYKHSHEGDHLESVVFIYSMPGYKCSIKERMLYSSCKNRLLDSVEQDFQLEIAKKIEIEDGAELTDEFLYDEVHPKQHAFKQAFAKPKGPAGKRGQKRLIKGPGENGEDS
What is the function of this protein?
Actin-binding protein involved in motile and morphological processes.  Inhibits actin polymerization, likely by sequestering G-actin (By similarity).
What are the official names of this protein?
Twinfilin-2-A.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Note=Perinuclear and G-actin-rich cortical actin structure sublocalization.
Protein: Y2269_METMJ
Sequence: MINILEVNETNKMIEQEKLDVRTITLGISLLDCCDSDLDAFNRNIYDKITRLGKDLVSTGREIELEYGIPIVNKRISVTPIALVAGRACRSEEDFVEVAKTLDKAARDTGVNFLGGYSAIVSKGTTPTDEALIRSIPAALAATGRVCSSVNIGSTKTGINMDAVKLMGEIVRETAEATKENNSLGCAKLVVFCNAPDDNPFMAGAFHGVSEADAVINVGVSGPGVIKHALEDVRGKNFEVLCETVKRTAFKVTRAGQLVAQEASERLGIPFGIVDLSLAPTPSVGDSVAGILEEMGLESVGAPGTTAALALLNDQVKKGGIMASSFVGGLSGAFIPVSEDQGMIDAVNRGALTIEKLEAMTCVCSVGLDMIAIPGDTPASTISGIIADEAAIGMINNKTTAVRLIPVIGKDLGDTVEFGGLLGHAPVQRVNGFGCADFINRGGRIPAPIHSFKN
What are the official names of this protein?
UPF0210 protein Memar_2269.
What is the protein family that this protein belongs to?
Belongs to the UPF0210 family.
Protein: HEMA_I02A4
Sequence: MEKIVLLLAIVSLVKSDQICIGYHANNSTEQVDTIMEKNVTVTHAQDILEKTHNGKLCDLDGVKPLILRDCSVAGWLLGNPMCDEFINVPEWSYIVEKANPANDLCYPGDFNDYEELKHLLSRINHFEKIQIIPKSSWSNHEASSGVSSACPYNGKSSFFRNVVWLIKKDNAYPTIKRSYNNTNQEDLLILWGIHHPNDAAEQTKLYQNPTTYISVGTSTLNQRLVPKIATRSKVNGQSGRMEFFWTILKPNDAINFESNGNFIAPEYAYKIVKKGDSAIMKSELEYGNCNTKCQTPMGAINSSMPFHNIHPLTIGECPKYVKSNRLVLATGLRNTPQRERRRKKRGLFGAIAGFIEGGWQGMVDGWYGYHHSNEQGSGYAADKESTQKAIDGVTNKVNSIINKMNTQFEAVGREFNNLERRIENLNKKMEDGFLDVWTYNAELLVLMENERTLDFHDSNVKNLYDKVRLQLRDNAKELGNGCFEFYHKCDNECMESVKNGTYDYPQYSEEARLNREEISGVKLESMGTYQILSIYSTVASSLALAIMVAGLSLWMCSNGSLQCRIC
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: PNP_METPB
Sequence: MFDVQREELIWGDRKLVLETGKTARQADGAVVATYGETTVLATVVAAKEPKAGIDFMPLTVNYQERAYAAGRIPGGYFKREGRPSEKETLVSRLIDRPIRPLFVEGWRNDTQVVVTVLSHDLENDPDIVSMVAASAALTLSGVPFMGPIGAARVGYLNGGYKLNPLVTEVAESTLDLVVAGTQDAVLMVESEAKELSEDVMLGAVMFGHKHFQPVIEAIIRLAEKAAKEPRDFSPPENADVEKAVLDICESELRDAYKITVKQDRYKAVDAVKAKVVAALCPAEGEQKFSPEKVKAAFKEAQSKVVRWNILDTGSRIDGRDVKTVRPIVSEVGVLPRAHGSSLFTRGETQALVVATLGTGEDEQFIDALEGTYKERFLLHYNFPPYSVGETGRMGSPGRREIGHGKLAWRAIRPVLPPAHEFPYTIRVVSEITESNGSSSMASVCGGSLSLMDAGVPLRRPVAGIAMGLILEGERFAVLSDILGDEDHLGDMDFKVAGTDEGITSLQMDIKIAGITEEIMRVALAQAKDGRAHILGEMAQALTAARPELGEYAPRIETMQIPTDKIRDVIGTGGKIIREIVEKTGAKINIEDTGVVKIASSDGKAIKAAYNWIRSIVAEPEAGTIYDGTIVKIMEFGAFVNFFGAKDGLVHISELAPQRVAKVGDVVKEGQKVKVKFLGADERGKIRLSMKVVDQETGEDITEKLKAERAERGEPEREERSDRGDRGDRGPRRDRGERRRESSGE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS8_METM7
Sequence: MSIDDKVRAIVKEFKAYVPGKSKEEIARNYGIDPEKIIKLGSNENPWGCSPKIAEKLMDEVSKLHQYPQPINPELMDEISKFTKMPVENIIVGGDGADEVIDNIMRILIDEGDEVIIPIPTFTQYAISAKIHGANIKWAKFDEENEFKLDIESVLNNITEKTKAIFLCTPNNPTGNVIPTEDIKKIVESTDALVMIDHAYIEYSNEDYDLTDWALKYDNVLVLRTFSKVFGLAGQRVGYGVTSKKIVDYMMRIKPIFSLTRASQASAITALQDKEFFEKCLNEGIESREEIYNGLKKFKQLEVYPTEANYMLVKVKNGMNSSEFCEVLLKKGVIVRDCYSFEGLEPYYFRVSIGTFDENERFLKIMSEVVE
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: RA213_ARATH
Sequence: MTTSMDFYSNKTFQQSDPFGGELMEALLPFIKSPSNDSSAFAFSLPAPISYGSDLHSFSHHLSPKPVSMKQTGTSAAKPTKLYRGVRQRHWGKWVAEIRLPRNRTRLWLGTFDTAEEAALAYDKAAYKLRGDFARLNFPDLRHNDEYQPLQSSVDAKLEAICQNLAETTQKQVRSTKKSSSRKRSSTVAVKLPEEDYSSAGSSPLLTESYGSGGSSSPLSELTFGDTEEEIQPPWNENALEKYPSYEIDWDSILQCSSLVN
What is the function of this protein?
Probably acts as a transcriptional activator.  Binds to the GCC-box pathogenesis-related promoter element.  May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
What are the official names of this protein?
Ethylene-responsive transcription factor RAP2-13, Ethylene-responsive transcription factor ERF058, Protein RELATED TO APETALA2 13.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: VEMP_CVHN5
Sequence: MVDVFFTDTAWYVGQIFFLVLSCVIFLIFVVALLATIKLCIQICGFCNIFIISPSAYVYNRGRQLYKSYSEHVIPSTLDDLI
What is the function of this protein?
Plays a central role in virus morphogenesis and assembly.  Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport.  Also plays a role in the induction of apoptosis.
What are the official names of this protein?
Envelope small membrane protein, E protein, sM protein.
What is the protein family that this protein belongs to?
Belongs to the betacoronaviruses E protein family.
What are the subcellular locations of this protein?
Host Golgi apparatus membrane; Single-pass type III membrane protein. Note=The cytoplasmic tail functions as a Golgi complex-targeting signal.
Protein: RL22_FUSNN
Sequence: MEAKAITRFVRLSPRKARLVADLVRGKSALEALDILEFTNKKAARVIKKTLSSAIANATNNFKMDEDKLVVSTIMVNQGPVLKRVMPRAMGRADIIRKPTAHITVAVSDEQ
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: CODY_BACC7
Sequence: MELLAKTRKLNALLQSAAGKPVNFREMSDTMCEVIEANVFVVSRRGKLLGYAIHQQIENERMKQMLAERQFPEEYTQSLFNITETSSNLDVNSAYTAFPVENKELFGQGLTTIVPIVGGGERLGTLVLARLGQEFLDDDLILAEYSSTVVGMEILREKAEEIEEEARSKAVVQMAISSLSYSELEAIEHIFEELNGTEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGTYIKVLNDKFLHELAKLKTN
What is the function of this protein?
DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability.  During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.
What are the official names of this protein?
Global transcriptional regulator CodY.
What is the protein family that this protein belongs to?
Belongs to the CodY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_AQUPY
Sequence: MSAVDPIADMFSAIKNAIMRRDAFLYVPSSKMKERILEVLKREGFIQDWEALKGEKYEEEFKKMKELAEKSPNPKMRRYLQQLIDYNKGTQYPLKIYLKYLDPKKRRSALTNIVRVSKGGRRVYAGVRTMPYVKRGLGIAIVSTDAGVMTDHEARKLRKGGEVIAFVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: ITIH1_HUMAN
Sequence: MDGAMGPRGLLLCMYLVSLLILQAMPALGSATGRSKSSEKRQAVDTAVDGVFIRSLKVNCKVTSRFAHYVVTSQVVNTANEAREVAFDLEIPKTAFISDFAVTADGNAFIGDIKDKVTAWKQYRKAAISGENAGLVRASGRTMEQFTIHLTVNPQSKVTFQLTYEEVLKRNHMQYEIVIKVKPKQLVHHFEIDVDIFEPQGISKLDAQASFLPKELAAQTIKKSFSGKKGHVLFRPTVSQQQSCPTCSTSLLNGHFKVTYDVSRDKICDLLVANNHFAHFFAPQNLTNMNKNVVFVIDISGSMRGQKVKQTKEALLKILGDMQPGDYFDLVLFGTRVQSWKGSLVQASEANLQAAQDFVRGFSLDEATNLNGGLLRGIEILNQVQESLPELSNHASILIMLTDGDPTEGVTDRSQILKNVRNAIRGRFPLYNLGFGHNVDFNFLEVMSMENNGRAQRIYEDHDATQQLQGFYSQVAKPLLVDVDLQYPQDAVLALTQNHHKQYYEGSEIVVAGRIADNKQSSFKADVQAHGEGQEFSITCLVDEEEMKKLLRERGHMLENHVERLWAYLTIQELLAKRMKVDREERANLSSQALQMSLDYGFVTPLTSMSIRGMADQDGLKPTIDKPSEDSPPLEMLGPRRTFVLSALQPSPTHSSSNTQRLPDRVTGVDTDPHFIIHVPQKEDTLCFNINEEPGVILSLVQDPNTGFSVNGQLIGNKARSPGQHDGTYFGRLGIANPATDFQLEVTPQNITLNPGFGGPVFSWRDQAVLRQDGVVVTINKKRNLVVSVDDGGTFEVVLHRVWKGSSVHQDFLGFYVLDSHRMSARTHGLLGQFFHPIGFEVSDIHPGSDPTKPDATMVVRNRRLTVTRGLQKDYSKDPWHGAEVSCWFIHNNGAGLIDGAYTDYIVPDIF
What is the function of this protein?
Contains a potential peptide which could stimulate a broad spectrum of phagocytotic cells.
What are the official names of this protein?
Inter-alpha-trypsin inhibitor heavy chain H1, ITI heavy chain H1, ITI-HC1, Inter-alpha-inhibitor heavy chain 1, Inter-alpha-trypsin inhibitor complex component III, Serum-derived hyaluronan-associated protein, SHAP.
What is the protein family that this protein belongs to?
Belongs to the ITIH family.
What are the subcellular locations of this protein?
Secreted.
Protein: YIDD_STRPZ
Sequence: MKKLLIVSVKAYQKYISPLSPPSCRYKPTCSAYMLTAIEKHGTKGILMGIARILRCHPFVAGGVDPVPEDFSLMRNKNTSKNAEKA
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL25_SHEWM
Sequence: MSYTIAAQVRTEIGKGSSRRLRHADKVPAVIYGPGKEPVAIVFDHKDIINIQENEDFYTSTLTINLDGSDVKVSVKAMQRHAFKPLIEHVDFTYA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: SPAST_DROER
Sequence: MVRTKNQSSSSSASSSSTKSPIKSSSGAGSSGGGVGGRQSTHRSSSASNVAAVVAGGSSAAGGGSSSNRRSPGSSPDGDDDTTTTDDLTPTTCSPRSGHHHTYGGYSSSVHKQNLYVVSFPIIFLFNVLRSLIYQLFCIFRYLYGASTKVIYRPHRRDCNIEIVVQNSSKEQQQSLNHPSELSREGDGQEQQLSNQPQRFRPIQPLEMAANRPGGGYSPGPGDPLLAKQKHHHRRAFEYISKALKIDEENEGHKELAIELYRKGIKELEDGIAVDCWSGRGDVWDRAQRLHDKMQTNLSMARDRLHFLALREQDLQMQRLSLKEKPKVQAPSKPQKTREPMLAGMTNEPMKLRVRSSGYGPKATTSAQPTASGRKLTIGSKRPVNLAVANKSQTLPRNLGSKTSVGAVQRQPAKTAATPPAVRRQFSSGRNTPPQRSRTPINNNGPSGSGASTPVVSVKGVEQKLVQLILDEIVEGGAKVEWTDIAGQDVAKQALQEMVILPSVRPELFTGLRAPAKGLLLFGPPGNGKTLLARAVATECSATFLNISAASLTSKYVGDGEKLVRALFAVARHMQPSIIFIDEVDSLLSERSSSEHEASRRLKTEFLVEFDGLPGNPDGDRIVVLAATNRPQELDEAALRRFTKRVYVSLPDEQTRELLLNRLLQKQGSPLDTEALRRLAKITDGYSGSDLTALAKDAALEPIRELNVEQVKCLDISAMRAITEQDFHSSLKRIRRSVAPQSLNSYEKWSQDYGDITI
What is the function of this protein?
ATP-dependent microtubule severing protein.  Stimulates microtubule minus-end depolymerization and poleward microtubule flux in the mitotic spindle.  Regulates microtubule stability in the neuromuscular junction synapse.  Involved in lipid metabolism by regulating the size and distribution of lipid droplets.  Involved in axon regeneration by regulating microtubule severing.
What are the official names of this protein?
Spastin.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. Spastin subfamily.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton. Chromosome. Lipid droplet. Note=Forms an intramembrane hairpin-like structure in the membrane. Colocalizes with cellular microtubule arrays. Localizes to chromosomes from prometaphase/metaphase to anaphase, and this requires microtubules. Localizes to discrete punctate cytoplasmic foci which may correspond to secretory vesicles.
Protein: Y1708_STAAM
Sequence: MTKISKIIDELNNQQADAAWITTPLNVYYFTGYRSEPHERLFALLIKKDGKQVLFCPKMEVEEVKASPFTGEIVGYLDTENPFSLYPQTINKLLIESEHLTVARQKQLISGFNVNSFGDVDLTIKQLRNIKSEDEISKIRKAAELADKCIEIGVSYLKEGVTEREVVNHIEQTIKQYGVNEMSFDTMVLFGDHAASPHGTPGDRRLKSNEYVLFDLGVIYEHYCSDMTRTIKFGEPSKEAQEIYNIVLEAETSAIQAIKPGIPLKDIDHIARNIISEKGYGEYFPHRLGHGLGLQEHEYQDVSSTNSNLLEAGMVITIEPGIYVPGVAGVRIEDDILVTNEGYEVLTHYEK
What are the official names of this protein?
Uncharacterized peptidase SAV1708.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.