PharMolix/UniProtQA huggingface dataset:
Protein: NADD_ANADE
Sequence: MSGGREIALLGGSFNPPHVAHLMAAWWALATQGVSEVWLLPAFRHPFGKELAPFEDRLEMCRLAARALRGVHVCGAEAELAGDPLVGKTARTLEHLAAKHPTYRFALVVGADILAETAKWYRWDRVQELARIIVVGRQGHPPVPGAPDLPAISSTEIRARLARGEDVRGLVPDRVLRYVEAQRLYRG
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: YCGG_BACSU
Sequence: MVNGIYTKSFLERIQEELPEWQRIAFELLAETLGDDADTFPCIPGRQAFLTDQLRIAFAGDPRENRTAEELAPLLAEYGKISRDTGKYASLVVLFDTPEDLAEHYSIEAYEELFWRFLNRLSHQDEKEWPEDIPADPEHYKWEFCFDGEPYFILCATPGHEARRSRSFPFFMVTFQPRWVFDDLNGSTAFGRNMSRLIRSRLEAYDQAPIHPQLGWYGGKDNREWKQYFLRDDEKQVSKCPFSYLKNMFNKMK
What are the official names of this protein?
Uncharacterized protein YcgG.
What is the protein family that this protein belongs to?
Belongs to the DcsA family.
Protein: VE2_HPV53
Sequence: METLCQRLDACQEKILDCFERDSKNITDHIDYWKAVRQENVIYYKARENNMTKLGHQVVPCLQVCKAKACVAIELQIALESLCKTEYNMEEWTLRDVCESMWYTEPKQCFKKQGQHIEVWFDGSKDNRAEYVVWKWVYYCGEDGWCKVSSAVSYEGIYYIHDGHKTYYTNFKDEATKYGCKGTWEVHMGKQSIYCPDSVSSTFRSNVSSVETVNEYYSHKTPTTSTPVGTYEASSSLRPGKRPRTTEPDSTDSTTQSTTTARESYAECVARNTDNTNNNTRKHLPGGASCNNTEIDSGYKTAPVVHIKGEANRLKCLRYRFQKHKQLFVTVSSTYHWTNVNCAVNNSYITVVYKDETQRQKFLDIVKIPPSVSLVLGHMTCVDM
What is the function of this protein?
Plays a role in the initiation of viral DNA replication.  A dimer of E2 interacts with a dimer of E1 in order to improve specificity of E1 DNA binding activity.  Once the complex recognizes and binds DNA at specific sites, the E2 dimer is removed from DNA.  E2 also regulates viral transcription through binding to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory regions of the viral genome.  Activates or represses transcription depending on E2RE's position with regards to proximal promoter elements including the TATA-box.  Repression occurs by sterically hindering the assembly of the transcription initiation complex.
What are the official names of this protein?
Regulatory protein E2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E2 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: NAGZ_THIDA
Sequence: MTLGPLMLDVAGTELCDDDRRRLSDPLVGGVILFSRNYRDPAQLAALCEEIHALKAAPLLIGVDHEGGRVQRFRDGFTRLPPMRSLGAIWNEHPQRARELARETGYVLASELRAHGVDFSFAPVLDLDYGASSVIGDRAFHADPQAVFQLGQAVMLGMKDAGMAACGKHFPGHGFVIADSHVDIPVDRRTLGDIARADLVPFRLMVEAGLAAMMPAHVIYPEVDAQPAGFSRVWLQKILRQQLGFDGAVFSDDLCMAGAAFAGGIVERVRAALDAGCDMALVCNHPELADEVLAKLDVDWPAPARARLARMHGHPAHAPTMTALRESARYAEALHHVAGLGRDSAELDLSDPTDYCGRA
What is the function of this protein?
Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.
What are the official names of this protein?
Beta-hexosaminidase, Beta-N-acetylhexosaminidase, N-acetyl-beta-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLY_STRP7
Sequence: MAKNTKLWGGRFEGTVEDWVERFGASISFDQKLAKFDVIGSLAHVQMLGQTGILSLEESEKIQVGLKELLEELEAGQLDFDIANEDIHMNMEVLLTEKIGPLAGKLHTARSRNDQVATDMHLYLKEQLGYVLDKLAHLKGVLLDLAENHVATIMPGYTHLQHAQPISFAHHLMAYYNMFQRDSERFEFNQKHTDLCPLGAAALAGTTFPIDRQLSSDLLEFKQPYTNSLDAVSDRDFILEFLSNASILMMHMSRFCEEMINWCSFEYQFITLSDTFTIGSSIMPQKKNPDMAELIRGKTGRVYGHLFGLLTVMKSLPLAYNKDLQEDKEGMFDTVETILNSLDVLAGMLSSLQVNKEKMQESTEKDFSNATELADYLAGKGLPFREAHEVVGRLVLDSIKSAKNLQDWTLEELQTYHSLITEDIYVYLQPKTAVQRRNSLGGTGFDQVEYQIAVAKKANEAKK
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_LIAPA
Sequence: MPHHYILTLFGLLPVATNISTWWNFGSMLLTCLALQVLTGFFLAVHYTANINLAFSSIIHITRDVPYGWMMQNLHAIGASMFFICIYIHIARGLYYGSYLNKETWMSGITLLITLMATAFFGYVLPWGQMSFWAATVITNLLTAVPYLGTSLTTWLWGGFAINDPTLTRFFALHFILPFEIISLSSLHIILLHEEGSSNPLGTNPDIDKIPFHPYHSHKDLLLLTLMILLLFITMSFFPDIFNDPDNFSKANPLVTPQHIKPEWYFLFAYGILRSIPNKLGGALALVTSIMILFTIPFTHTAHLRPMTFRPLSQLMFWTLVSTFITITWAATKPVEPPFIIISQATSLLYFTFFLSFPILGWTENKMMNTP
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CLPX_SACD2
Sequence: MSDHTGDNEDNGKLLYCSFCGKSQHEVRKLIAGPSVFICDECVDLCNDIIREEIQESTTESTGDKLPTPQEISETLDEYVIGQKQAKKVLAVAVYNHYKRLRVGDKKKSKDDVELGKSNILLVGPTGSGKTLLAETLARLLNVPFTIADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQQGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVDTGNILFICGGAFAGLDKVIRDRSEKGGIGFSAEVKSKDSGKNVGETLRELEPEDLVRYGLIPEFVGRLPVIATLDELDQDALVRILKEPKNSLVKQYSKLFEMEGSEVDFRDDALEAVANKAMERKTGARGLRSIMENVLLDTMYKIPSEENVVKVVVDESVIKGESAPLLVYGNNDAETAKAVPEE
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: GNAO_MANSE
Sequence: MGCASSAEERAAPSAQQADREKLKEDGIQAAKDIKLLLLGAGESGKSTIVKQMKIIHESGFTNEDFKQYRPVVYSNTIQSLVAILRAMPTLGITYANKDRESDGKMVFDVIQRMEDTEPFSEELLAAMKRLWADAGVQECFGRSNEYQLNDSAKYFLDDLDRLGARDYQPTEEDILRTRVKTTGIVEVHFSFKNLNFKLFDVGRGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFDSICNNKWFTDTSIILFLNKKDLFEEKIRKSPLTICFPEYTRAYQEYGEAAAYIRSQFEAKNNSTTKEIYCHMTATDTNNNQFVFDAVTDVIIANNLRGCGLY
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.  The G(o) protein function is not clear.
What are the official names of this protein?
Guanine nucleotide-binding protein G(o) subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family. G(i/o/t/z) subfamily.
Protein: Y9115_RHOBA
Sequence: MATNQFANRTRQTLAWITTCGERVRSWYEDYRFGSIDENAQLGRRGEQAAAQLLRRKGLNVIAESESDRAGEIDLIALRKRPRLIVFVEVKTLSTTRPGHPADRVDENKQARITRAALRYLKRKKLLGITCRFDVVAVWWPRDEPRPTRVEHYESAFNAVGVDSFYG
What are the official names of this protein?
UPF0102 protein RB9115.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: MATK_HUICH
Sequence: MEEFQRYFELNRYQQHNFLYPLIFQEYIAALAHDHGLNRSILLENTGYGNKFSLLSVKRLITQMYQQNHLIISANDSSQNQFFGHNKNLYSQMISEGFAVIVEIPFSLRLRSSLEGKEIVKSQNLQSIHSIFPFLEDKFLHLNYVLDILIPYPIHLEILVQTLRHWVKDASSLHLLRFFLHEYRNWNSLITPKKTSSSFSKRNQRLFFFLYNSHVCEYESIFIFILSQSSHLRSTSSGALLERIYFYGKIEHSVEVFAKDFPSILCLLKDPFIHYLRYQGKSILASKGTPLLMNKWKYYLVNSWQCHFYVWSQSRRIYINQLSNHFLDFLGYLSSVRLNPSMVRSQMLENSFLIDNAIKKFETIVPIIPLIGSLAKAKFCNVLGHPISKPVWADLSDSDIIDRFGRICRNLSHYHSGSSKKKSLYRIKYILRLSCARTLARKHKSTVRAFLKMKRVGSELLEKFFTEEEQVFSLTFPRVSSTSTSRGLYRRRIWYLDIICINDLANHE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: VM1LA_BOTLC
Sequence: QQFSPRYIELVVVADHGMFKKYNSNLNTIRKWVHEMLNTVNGFFRSMNVDASLVNLEVWSKKDLIKVEKDSSKTLTSFGEWRERDLLPRISHDHAQLLTVIFLDEETIGIAYTAGMCDLSQSVAVVMDHSKKNLRVAVTMAHELGHNLGMRHDGNQCHCNAPSCIMADTLSKGLSFEFSDCSQNQYQTYLTKHNPQCILNKP
What is the function of this protein?
Non-hemorrhagic metalloproteinase that hydrolyzes the alpha chains of fibrinogen, as well as fibrin, fibronectin and casein.  Beta and gamma chains are also hydrolyzed, but more slowly.  Thrombolytic activity is also observed.  Induces detachment of endothelial cells followed by death, and inhibits endothelial cell adhesion to fibronectin.  Induces edema in mouse paw.  Inhibits ADP-induced platelet aggregation on human platelet-rich plasma with an IC(50) of 2. 8 uM.
What are the official names of this protein?
Snake venom metalloproteinase leucurolysin-A, Leuc-A, SVMP.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-I subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SSRP_BRUA4
Sequence: MNKPKNSPVRKIIAENRKARFNFEILDTLEAGLVLTGTEVKSLRANQSNIAESYASFENGEFWLINSYIPEYTQGNRFNHEPRRLRKLLISKREMSRLFNSVSRDGMTVVPLKLYFNDRGRAKLELALARGKKTHDKRETEKKRDWNREKARLMRDKG
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: GARR_ECOL6
Sequence: MKVGFIGLGIMGKPMSKNLLKAGYSLVVADRNPEAIADVIAAGAETASTAKAIAEQCDVIITMLPNSPHVKEVALGENGIIEGAKPGTVLIDMSSIAPLASREISEALKAKGIDMLDAPVSGGEPKAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVVHTGEIGAGNVTKLANQVIVALNIAAMSEALTLATKAGVNPDLVYQAIRGGLAGSTVLDAKAPMVMDRNFKPGFRIDLHIKDLANALDTSHGVGAQLPLTAAVMEMMQALRADGLGTADHSALACYYEKLAKVEVTR
What is the function of this protein?
Catalyzes the reduction of tatronate semialdehyde to D-glycerate.
What are the official names of this protein?
2-hydroxy-3-oxopropionate reductase, Tartronate semialdehyde reductase, TSAR.
What is the protein family that this protein belongs to?
Belongs to the HIBADH-related family. 2-hydroxy-3-oxopropionate reductase subfamily.
Protein: MUTL_SYNAS
Sequence: MNRRIVLLPETLTHRIAAGEVVERPASIVKELLENALDSGATDINVELERGGCGLIRVADNGSGIFAQDVTLAFARHATSKIAEFDDLYRVRSFGFRGEALASIASISRTELVTRTADDLAGMRIVVEGGNICEKTEAGCPIGTSITVSRIFDSVPVRKKFLKAEATERAYCLDVITRLSLANPEVRIRVFSKGRELCHYPATSRLSERVALVLGNADADRLQPIEGETDRVRVTGFASRPDFTCATTRQIYTFVNRRHVRDHLLNHAVMTAYRRVIEPRRYPAVVLYVDLDPADVDVNVHPAKLEVRFRQPRTVYEAVVEALSGMLRGMGQSALSLTRYGPAGTAEIGHIPQEDYESRISEALRRYSLASGSRKMMYGTGTEANPVNKKHFLAERIRGEEIHARESLLLSPAPALPQNSFHPVFADLVYLGSLWDSYLIFSVADGMLLIDQHAAHERILFEKIKKAAERNKTAVQVLLIPEILNLSRPDFERFGDVVPLLEQVGIEAEPFGGEEIIIKALPTLLAHLDPGVLVKDLIAECADRGGGLSLQEKGEKIYAYLACRGAVKAGQKLIREEVAQLCRDLDATPFAATCPHGRPVYVLYPLKDIERMFRRR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: UBIG_XYLFA
Sequence: MSSAYDRVSKNYRQSELDKFAAFTSGWWDPHGPQKPLHALNPVRLDYISKRVPLSGARVLDVGCGGGLLSEALARQGAHVTAIDLAPELIKVARLHGLESGIQVDYRIQAIEDLLAEQPAPFDAIACMEMLEHVPDPAAIVDACAHLLKPGGRLFVSTINRTLAAFMLAVVGAEYVVRLLPKGTHQYKDFIRPAELAAWLRHAGLHLEDVSGMRYEPWRNRARLTDRTDINYLACAISPEAPHATE
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: MDH_ECOBW
Sequence: MKVAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAVDLSHIPTAVKIKGFSGEDATPALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKNLVQQVAKTCPKACIGIITNPVNTTVAIAAEVLKKAGVYDKNKLFGVTTLDIIRSNTFVAELKGKQPGEVEVPVIGGHSGVTILPLLSQVPGVSFTEQEVADLTKRIQNAGTEVVEAKAGGGSATLSMGQAAARFGLSLVRALQGEQGVVECAYVEGDGQYARFFSQPLLLGKNGVEERKSIGTLSAFEQNALEGMLDTLKKDIALGEEFVNK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: TERF1_MOUSE
Sequence: MAETVSSAARDAPSREGWTDSDSPEQEEVGDDAELLQCQLQLGTPREMENAELVAEVEAVAAGWMLDFLCLSLCRAFRDGRSEDFRRTRDSAEAIIHGLHRLTAYQLKTVYICQFLTRVASGKALDAQFEVDERITPLESALMIWNSIEKEHDKLHDEIKNLIKIQAVAVCMEIGSFKEAEEVFERIFGDPEFYTPLERKLLKIISQKDVFHSLFQHFSYSCMMEKIQSYVGDVLSEKSSTFLMKAATKVVENEKARTQASKDRPDATNTGMDTEVGLNKEKSVNGQQSTETEPLVDTVSSIRSHKNALSQLKHRRAPSDFSRNEARTGTLQCETTMERNRRTSGRNRLCVSENQPDTDDKSGRRKRQTWLWEEDRILKCGVKKYGEGNWAKILSHYKFNNRTSVMLKDRWRTMKRLKLIS
What is the function of this protein?
Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and negatively regulates telomere length.  Involved in the regulation of the mitotic spindle.  Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection.  Shelterin associates with arrays of double-stranded 5'-TTAGGG-3' repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways.
What are the official names of this protein?
Telomeric repeat-binding factor 1, TTAGGG repeat-binding factor 1.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere. Cytoplasm, cytoskeleton, spindle. Note=Colocalizes with telomeric DNA in interphase and prophase cells. Telomeric localization decreases in metaphase, anaphase and telophase. Associates with the mitotic spindle (By similarity).
Protein: YSH1_EMENI
Sequence: MAAKRKAAAMNAVDDEPVDPSDELAFYCLGGGNEVGRSCHIIQYKGKTVMLDAGMHPAKEGFSALPFFDEFDLSTVDILLISHFHVDHSSALPYVLSKTNFKGRVFMTHATKAIYKWLIQDNVRVNNTASSSDQRTTLYTEHDHLSTLPLIETIDFNTTHTINSIRITPYPAGHVLGAAMFLISIAGLNILFTGDYSREEDRHLIPATVPRGVKIDVLITESTFGISSNPPRLEREAALMKSITGVLNRGGRVLMPVFALGRAQELLLILEEYWETHPELQKIPIYYIGNTARRCMVVYQTYIGAMNDNIKRLFRQRMAEAEASGDKSVSAGPWDFKYVRSLRSLERFDDVGGCVMLASPGMLQTGTSRELLERWAPNERNGVVMTGYSVEGTMAKQLLNEPDQIHAVMSRAATGMGRTRMNGNDEEQKIMIPRRCTVDEISFAAHVDGVENRNFIEEVSAPVVILVHGEKHQMMRLKSKLLSLNAEKTVKVKVYTPANCEEVRIPFRKDKIAKVVGKLAQTTLPTDNEDGDGPLMAGVLVQNGFDLSLMAPDDLREYAGLATTTITCKQHITLSSASMDLIKWALEGTFGAIEEIGTDEDAEKEDQQSESEEKQRMKEEADEEIPMEKPQAYLVMGCVVIRYHPRTREVELQWEGNMMNDGIADAVMAVLLTVESSPASVKQSAKHNKHHHHHHHDETDTLKFLNPHAAQDAEERFARLLMMLEAQFGSDIAPIERPRVPSSTESATTTTNGNGNSKSDSEQLSSLESKTDGATPQDPDTLSELEAAELSRLHALGIPVPGIEIKVDKHVARVWLEDLEVECANAVLRDRVRVVIERAVETVASMWSVGRSSKTITNGGGKEIAGTGADDVASKPGLEVAARA
What is the function of this protein?
Component of the cleavage factor I (CF I) involved in pre-mRNA 3'-end processing.
What are the official names of this protein?
Endoribonuclease ysh1, mRNA 3'-end-processing protein ysh1.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SDSA_RHOCA
Sequence: MAIDFKQDILAPVAQDFAAMDQFINEGISSKVALVMSVSKHVVEAGGKRMRPIMCLLAAYACGETNLKHAQKLAAIIEMLHTATLVHDDVVDESGLRRGRPTANATWNNQTAVLVGDFLIARAFDLLVDLDNMILLKDFSTGTCEIAEGEVLQLQAQHQPDTTEDIYLQIIHGKTSRLFELATEGAAILAGKPEYREPLRRFAGHFGNAFQIIDDILDYTSDADTLGKNIGDDLMEGKPTLPLIAAMQNTQGEQRDLIRRSIATGGTSQLEQVIAIVQNSGALDYCHKRATEETERALQALEILPESTYRQALVNLTRLALDRIQ
What is the function of this protein?
catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with the allylic substrate to give solanesyl diphosphate.  Could be important to determine the side chain length of ubiquinone.
What are the official names of this protein?
All-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific), Solanesyl diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
Protein: AES1_HYPJE
Sequence: MRSILVIPSFVAVLNAFSLFPKPHDDFKYLITFGDSYTDNGRLGYYGSHQAHGPPPGVMPPEANVTASGGLQWPQYVEASTGATLYDYAIAGATCDNNNVERWAAFMNANYPSIITDEIPSFKADRKTKLYRGVTSANTVYALWIGTNDLSYTGILSDSQVKGTNITTYIDCLWNVFDAIHAAGGRRFVILNNNALQLTGLYRPLSDGGAGDNQFWQNKTLYNQTEYAQKMLEYTTSSNTMIDYGVPFHLLVKNRWPGSKVAVYDIHSLIMDIYNQPSRYLEPPHNVVGYYKHCDVNGTNCLYGPGRLDSYLWYDELHPSNIIASYIAREFLNVVSGRSKYGTYWEHW
What is the function of this protein?
Acetylesterase that acts as an exo-deacetylase (PubMed:24140638).  Shows activity towards naphtyl acetate, triacetin, as well as towards glucose- and xylose acetates (PubMed:18978092, Ref. 2).  Liberates acetic acid from xylo-oligomers (PubMed:18978092, Ref. 2, PubMed:24140638).
What are the official names of this protein?
Acetylesterase, Carbohydrate esterase family 16 protein.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate esterase CE16 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SEPT3_DANRE
Sequence: MSEIVPPEVRPKPAVPAKPSHVAPPSSAPFVPSPQGTGGEGQGSGRGSALLGYIGIDTIIEQMRKKTMKAGFDFNIMVVGQSGLGKSTLVNTLFKSQVSRRSTSWSRDEKIPKTVEIKSVSHVIEEGGVKMKLTVVDTPGFGDQINNDNCWEPISKHINEQYEKFLKEEVNIARKKRIPDTRVHCCLYFISPTGHSLRQLDIEFMKHLSRVVNIIPVIAKSDTLTPEEKTEFKQRVRKELEVCGIECYPQKEFDEDMEDKSDNDKIRETMPFAVVGSDKEYQVNGKRVLGRKTAWGVVEVENPNHCEFSLLRDFMIRSHLQDLKEVTHNIHYETYRAKRLNDNGGLHPISSSGHDTQESNL
What is the function of this protein?
May be involved in cytokinesis.
What are the official names of this protein?
Neuronal-specific septin-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXD_BACFR
Sequence: MEFSAKQIAAFIQGEIIGDENATVHTFAKIEEGIPGAISFLSNPKYTPYIYETKASIVLVNKDFTPEQEVKATLIKVDNAYESLAKLLNLYEMSKPKRTGIDERAYVAETAKIGKDVYIAPFACIGDHAEIGDNTVIHPHATVGGGAKIGSNCILYANSTVYHDCRVGNNCILHAGCVIGADGFGFAPTPQGYEKIPQIGIVILEDNVEVGANTCIDRATMGATVIHSGVKLDNLVQIAHNDEIGSHTVMAAQVGIAGSTKVGEWCMFGGQVGIAGHLKIGNQVNLGAQSGVPGNIKSGSQLIGTPPMELKQFFKASIVQKSLPEMQIELRNLRKEIEELKQQLNK
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: GLPG_ECO81
Sequence: MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDVWLADESQAERVRAELARFLGNPADPRYLAASWQSGHTDSGLHYRRYPFFAALRERAGPVTWVMMIACVVVFIAMQILGDQEVMLWLAWPFDPTLKFEFWRYFTHALMHFSLMHILFNLLWWWYLGGAVEKRLGSGKLIVITLISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLIIFALIWIVAGWFDLFGMSMANGAHIAGLAVGLAMAFVDSLNARKRK
What is the function of this protein?
Rhomboid-type serine protease that catalyzes intramembrane proteolysis.
What are the official names of this protein?
Rhomboid protease GlpG, Intramembrane serine protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS20_LEPIC
Sequence: MANIKSSEKDIRRTKRRNAANSQNRSRLRTQAKKVLKAIKEKDQKAAMTLFIEYTSLLDKAAKTNLIHSKNADRKKSRMAKRLNSSAA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: BENB_ACIAD
Sequence: MNATALLDTISIEQISQFLYSEARFLDDEQWDDWLECYAPQASFWMPAWDDNDQLTENPQTEISLIYYPDRQGLEDRVFRIKTERSSATMPDTRTAHNISNIEVESRDGLQITVRFNWNTLSFRYKNSYSYFGMSRYVIDFSGEQPKILSKYVMLKNDYINQVIDIYHI
What is the function of this protein?
Degradation of benzoate to 2-hydro-1,2-dihydroxybenzoate (DHB).  The beta subunit may be responsible for the substrate specificity of the enzyme.
What are the official names of this protein?
Benzoate 1,2-dioxygenase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.
Protein: RF1_UREP2
Sequence: MEYNKKLYEAIERVAIKNDALKKELETVVTDFKKIKEINIQLKKTTKIAEAFAKYKQKLDTGIAAEKILNTEKDLELIELAQMDLDEAKINIPIIENDLKIMLLPTDPNDDKNVIVEMRPAAGGDESSIFVGNLFDTYRAYAENNNWKMKIIEMTPNAVGFSFISFMISGEEVYSRMKFESGVHRVQRVPATESKGRVHTSTITVAVLPEQDEVDVVINPTELRIDTYRASGAGGQHVNRTESAVRITHIPTGVVAACQEGKSQIENRETAMKMLRAKLWEAAQEQQNAEFANLRKNQVGTGDRSEKIRTYNYPQNRVTDHRINLTLNKLDQIMMGELDEIIDALIADEQTGLMANLDI
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MODC_BRUA2
Sequence: MSGLTVSIRGRNGAFAIEAGFAAEGGVTALFGHSGAGKTTLLKMIAGTLRPENGRIAVGDFTLFDAQKGINLPPEKRRIGYVFQDARLFAYMSVKRNLTYARWAGHRPATRSFDEVVALLGIGHLLDRRPSTLSGGERQRVAIGRALLSDPALLLLDEPLSSLDHARRQEILPFIERLRDESHVPIVYVSHEIDEVARLADQIVLLSAGRVTASGAAADIFPLIDAESEGGGVLLEGIVSAYDERYKLAEIDLGGASFQLSDAGLKQTMHVRLRVRARDVSIARKIPEAISIRNLLPVTVTGIERGEGPNAHVFLDFRGRRLGARLTRRSVDDLGLSVGDQVVALVKAVSVDRAAIREK
What is the function of this protein?
Part of the ABC transporter complex ModABC involved in molybdenum import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Molybdenum import ATP-binding protein ModC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.