PharMolix/UniProtQA huggingface dataset:
Protein: NTH2_ARATH
Sequence: MILTGAASTFPIVARVLNAMNRRMYAATTLSSAKSISAESLNLRSDSNSEAAHGASESETRVSLRKKRIKQDDLEPVKKCSARETKARKDMCGLPDIEDSPYKKTNGTASSRTRKLNSYIKSTEASPSASSIKTAGLGIPPENWEKVLEGIRKMKPSEEAPVNAVECDRTGSFLPPKERRFYVLIGTLLSSQTKEHITGAAVERLHQNGLLTPEAIDKADESTIKELIYPVGFYTRKATNVKKVAKICLMEYDGDIPRTLEELLSLPGVGPKIAHLVLHVAWNDVQGICVDTHVHRICNRLGWVSKPGTKQKTSSPEETRVALQQWLPKGEWVAINFLLVGFGQTICTPLRPHCGTCSITEICPSAFKETPSTSSKLKKSIKSKKL
What is the function of this protein?
Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage.  The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site.  The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination.  Primarily recognizes and repairs oxidative base damage of pyrimidines.
What are the official names of this protein?
Endonuclease III homolog 2, chloroplastic, AtNTH2, Bifunctional DNA N-glycosylase/DNA-(apurinic or apyrimidinic site) lyase 2, DNA glycosylase/AP lyase 2.
What is the protein family that this protein belongs to?
Belongs to the Nth/MutY family.
Protein: RS10_HAES1
Sequence: MQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLISPHVNKDARDQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLG
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: DMB_SQUAC
Sequence: MEENMEEGQTQKGCFECCIKCLGGIPYASLIATILLYAGVALFCGCGHEALSGTVTILQNNFEVVRGAGDTIDVFTMIDIFKYVIYGVAAAFFVYGILLMVEGFFTTGAIKDLYGDFKITTCGRCVSGWFIMLTYIFMLAWLGVTAFTSLPVFMYFNIWTLCQNVTIMESTDLCFDLRQFGIVPIHEQKTVCTLNENFSKLCQSNDLNMTFHLFIVALAGAGAAVIAMVHYLMVLSANWAYVKDACRMQKYEDIKSKEEQELHDIHSTRSKERLNAYT
What are the official names of this protein?
Proteolipid protein DM beta.
What is the protein family that this protein belongs to?
Belongs to the myelin proteolipid protein family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: T2R41_HUMAN
Sequence: MQAALTAFFVLLFSLLSLLGIAANGFIVLVLGREWLRYGRLLPLDMILISLGASRFCLQLVGTVHNFYYSAQKVEYSGGLGRQFFHLHWHFLNSATFWFCSWLSVLFCVKIANITHSTFLWLKWRFPGWVPWLLLGSVLISFIITLLFFWVNYPVYQEFLIRKFSGNMTYKWNTRIETYYFPSLKLVIWSIPFSVFLVSIMLLINSLRRHTQRMQHNGHSLQDPSTQAHTRALKSLISFLILYALSFLSLIIDAAKFISMQNDFYWPWQIAVYLCISVHPFILIFSNLKLRSVFSQLLLLARGFWVA
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 41, T2R41, Taste receptor type 2 member 59, T2R59.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CF251_HUMAN
Sequence: MSDAAEAPREATGENGETEMKEEEEPNPNYKEVEDPQQESKDDTIAWRESQEEERKTGEEEGEEEGKEDKKIVMEETEEKAGEVQEKEASGIQEETTVEPQEVTASMIRLETQITDSQSITSGIFPKTQRGSKSKLSLQLEDAETDELLRDLSTQIEFLDLDQISPEEQQISSPERQPSGELEEKTDRMPQDELGQERRDLEPENREEGQERRVSDIQSKAGISRESLVSSTTEDILFQKDKSTPVYPLTMTWSFGWNSSLPVYYIREERQRVLLYVCAHTAIIYNVFRNNQYHLQGHANIISCLCVSEDRRWIATADKGPDCLVIIWDSFTGIPVHTIFDSCPEGNGIMAMAMTHDAKYLATISDAEVQKVCIWKWTLAVETPACTLELPTEYGVQNYVTFNPTNNKELVSNSKTRAIYYAWYEERDTLAHSAPLLTEKTFNKLVGKFSQSIFHLNLTQILSATMEGKLVVWDIHRPPSSASTFLGFPYIKPCKLVHLQKEGITVLTTIDSYIVTGDIKGNIKFYDHTLSIVNWYSHLKLGAIRTLSFSKTPATPPTEKSNYPPDCTLKGDLFVLRNFIIGTSDAAVYHLTTDGTKLEKLFVEPKDAICAISCHPYQPLIAIGSICGMIKVWNYENKQYLFSRVFEKGLGVQSLTYNPEGALLGAGFTEGTVYILDAMSLENESPEPFKYSRTSVTHISFSHDSQYMATADRSFTVAVYMLVVRNGQRVWEYLARLRSHRKSIRSLLFGVYLDSNEPRLLSLGTDRLLIEYDLLRSYKDHLEVLDIHHTDQGCYPTCMVWYPPLTRELFLLICNSGYKVKLFNATTKMCRKTLLGPAYGSPIEQTQVLPVRSMAELQKRYLVFINRDKVGLQILPVDGNPHKTSAIVCHPNGVAGMAVSYDGCYAFTAGGHDRSVVQWKITLSVLEAAVSLGGEDLTPFYGLLSGGREGKFYRELEDYFYYSQLRSQGIDTMETRKVSEHICLSELPFVMRAIGFYPSEEKIDDIFNEIKFGEYVDTGKLIDKINLPDFLKVYLNHKPPFGNTMSGIHKSFEVLGYTNSKGKKAIRREDFLRLLVTKGEHMTEEEMLDCFASLFGLNPEGWKSEPATCSVKGSEICLEEELPDEITAEIFATEILGLTISEDSGQDGQ
What is the function of this protein?
Involved in spermatozoa motility (PubMed:30122540, PubMed:30122541).  May also regulate cilium motility through its role in the assembly of the axonemal radial spokes (By similarity).
What are the official names of this protein?
Cilia- and flagella-associated protein 251, WD repeat-containing protein 66.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Cell projection, cilium, flagellum.
Protein: RDGC_ERWT9
Sequence: MLWFKNLMVYRLNRDIPLVADEMEKQLDAFSFTPCGSQDMAKTGWVSPLGAHGEDLTHVTNGQILICARKEEKMLPSPVIKQALEAKISKLEAEQSRKLKKTEKDSLKDEVLHSLLPRAFSRFSQTCVWIDTVNNLIMVDCASAKKAEDTLALLRKSLGSLPVVPLTLESPIELTLTEWVRSGELPAGFALMDEAELKAILEDGGVIRCKKQDLVCDEIANHIEAGKLVTKLALDWQERIQMILSDDGSIKRLKFSDILREQNDDIDREDVTGRFDADFILMTGELAALISNTVEALGGEAQR
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: 192R_IIV6
Sequence: MSFKKLTNVWNVQEQLSLSNATYNKNLELEKRLAKIRNEIPNKSKLIATKVDVSTQTKTVKKFTKRGFKKVLI
What are the official names of this protein?
Uncharacterized protein 192R.
Protein: DAP1_HUMAN
Sequence: MSSPPEGKLETKAGHPPAVKAGGMRIVQKHPHTGDTKEEKDKDDQEWESPSPPKPTVFISGVIARGDKDFPPAAAQVAHQKPHASMDKHPSPRTQHIQQPRK
What is the function of this protein?
Negative regulator of autophagy.  Involved in mediating interferon-gamma-induced cell death.
What are the official names of this protein?
Death-associated protein 1, DAP-1.
Protein: CDH_ECO5E
Sequence: MKKAGLLFLVMIVIAVVAAGIGYWKLTGEESDTLRKIVLEECLPNQQQNQNPSPCAEVKPNAGYVVLKDLNGPLQYLLMPTYRINGTESPLLTDPSTPNFFWLAWQARDFMSKKYGQPVPDRAVSLAINSRTGRTQNHFHIHISCIRPDVREQLDNNLANISSRWLPLPGGLRGHEYLARRVTESELVQRSPFMMLAEEVPEAREHMGSYGLAMVRQSDNSFVLLATQRNLLTLNRASAEEIQDHQCEILR
What are the official names of this protein?
CDP-diacylglycerol pyrophosphatase, CDP-diacylglycerol phosphatidylhydrolase, CDP-diglyceride hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Cdh family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: UTP25_HUMAN
Sequence: MGKRGSRSQSQLLNTLTKKQKKHLRDFGEEHPFYDRVSRKEAKPQICQLSESSDSSDSESDSESEPQQVSGYHRLLATLKNVSEEEEEDEEEEEEEDSIVDDAEMNDEDGGSDVSVEEEMAAESTESPENVALSADPEGKEDGEEPPGTSQTSPEEFTDAKHESLFSLETNFLEEESGDNSSLKASQDPFLQHVNKELKEKAIQAVATNPKTTHELKWPILGQLFFSSKFQKLETFKPPKDIDLKSLHLQKPLESTWTKTNSQFLSGPQKSSSPFTPLQKELFLIMNSYRDLFYPERTALKNGEEIRHVYCLHVINHILKANAQVLGNNSRRRSQKFGVGDDDDFRDQGLTRPKVLIVVPFREAALRVVQLFISLLEGDSKKKIIVSNKKRFQGEYGSDPEERPPNLKRPEDYEAVFVGNIDDHFRIGVAILQRSIRLYAPFYSSDILIASPLGLRTIIGGEGEKKRDFDFLSSIELLIIDQADIYLMQNWEHVLHLMNHMNLLPLDSHGVDFSRVRMWSLNNWSKYYRQTLLFGALQDAQINSVFNKYCVNMQGQVAVRNVPMTGSISHVLVQLPHVFQRMEAENLASVIDARFNFFVNKILPQYRDAVMSHTLIYIPSYFDFVRLRNYFKKEELNFTHICEYTQKSGVSRARHFFLQGEKQFLLFTERFHFYKRYTIKGIRNLIFYELPTYPHFYSEICNMLRATNRGEEATWTCTVLYSKYDAQRLAAVVGVERAAQMLQSNKNVHLFITGEK
What is the function of this protein?
Component of the ribosomal small subunit processome for the biogenesis of ribosomes, functions in pre-ribosomal RNA (pre-rRNA) processing (By similarity).  Essential for embryonic development in part through the regulation of p53 pathway.  Controls the expansion growth of digestive organs and liver (PubMed:25007945, PubMed:27657329, PubMed:23357851).  Also involved in the sympathetic neuronal development (By similarity).  Mediates, with CAPN3, the proteasome-independent degradation of p53/TP53 (PubMed:23357851, PubMed:27657329).
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 25 homolog, Digestive organ expansion factor homolog, UTP25 small subunit processor component.
What is the protein family that this protein belongs to?
Belongs to the UTP25 family.
Protein: POL_IPMAI
Sequence: MALTPADWQMIAKAALPNMGKYLEWRSLWREAAQAQARANAAALTPEQRDWTFDLLTGQRAYSAKPDKRYQWKVLPQGMSNSPTMCQLYVQKALLPVREQFPSLILLLYMDDILLCHKDLTMLQKAYPFLLKTLSQWGLQIATEKVQISDTGQFLGSVVSPDKIVPQKVEIRRDHLHTLNDFQKLLGDINWLRPFLKIPSAELRPLFSILEGDPHISSPRTLTLAANQALQKVEKALQNAQLQRIEDSQPFSLCVFKTAQLPTAVLWQNGPLLWIHPNVSPAKIIDWYPDAIAQLALKGLKAAITHFGQSPYLLIVPYTAAQVQTLAAASNDWAVLVTSFSGKIDNHYPKHPILQFAQNQSVVFPQITVRNPLKNGIVVYTDGSKTGIGAYVANGKVVSKQYNENSPQVVECLVVLEVLKTFLKPLNIVSDSYYVVNAVNLLEVAGVIKPSSRVANIFQQIQLVLLSRRSPVYITHVRAHSGLPGPMALGNDLADKATKVVAAALSSPVEAARNFHNNFHVTAETLRSRFSLTRKEARDIVTQCQSCCEFLPVPHVGINPRGIRPLQVWQMDVTHVSSFGKLQYLHVSIDTCSGIMFASPLTGEKASHVIQHCLEAWSAWGKPRLLKTDNGPAYTSQKFQQFCRQMDVTHLTGLPYNPQGQGIVERAHRTLKAYLIKQKRGTFEETVPRAPRVSVSLALFTLNFLNIDAHGHTAAERHCSEPDRPNEMVKWKNVLDNKWYGPDPILIRSRGAICVFPQNEDNPFWVPERLTRKIQTDQGNTNVPRLGDVQGVNNKERAALGDNVDISTPNDGDV
What are the official names of this protein?
Intracisternal A-particle Pol-related polyprotein.
What is the protein family that this protein belongs to?
Belongs to the retroviral Pol polyprotein family.
Protein: EF102_EPIFF
Sequence: MSGHGDKDRDRKLGSQHSTLHERGFGGNGAVDAEQESSMSDNEQPTEYRTYRRRWIGLLTLTLMNVVVSWDWLTFAPVADLSATYYGVSKLAINWVSIAFFLAFVAVFPITIAILHRGPKLAFMIAAVLIIIGNWVRYAGSASSTGGRYGAIMAGEIIIGFAQPFILAAPTRYSDMWFTNRGRVAATALTSLANPLGGALGQLINPRWAKQSADISNMVLYVSIISTVCSLPAFVVPAAPPTPVGPAAETPKLSLKESLKVLTHSIELWLVLIPFFVYVGFFNSISSLLNQIMIPYGFSDDEAGIGGAILILVGLLFSAVTSPIIDRTKKFLLALKLFMPVIGICYLTFVWMPETRNVAGPYAVLAVLGAASFALVPIALEFLTELGHPLSPEVTSTTAWAGGQLLGAIFVIISGALTAGDDGNPPQNMNRALVFQAVVALLVCPLPLFLGLFGRGDKIILKRVRSDTRGVPSGVRIIA
What is the function of this protein?
MFS-type transporter; part of the gene cluster that mediates the biosynthesis of peramine, a pyrrolopyrazine synthesized in association with the grass host that protects the plant from insect herbivory (PubMed:16091042).  Probably involved in peramine transport (PubMed:16091042).
What are the official names of this protein?
MFS-type transporter EF102, Peramine biosynthesis cluster protein EF102.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PRT_PHOTU
Sequence: ARAVRRRRARSRSRSRKSRSRSRSAKRSASRRRSRSAGRRRRRRTASRRRRRSASRRRSVSRRRRRRSRKSRGRRRRGRKVRRRRVKRAGRKGRRRTRRRRRRARR
What are the official names of this protein?
Protamine.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: CP17A_RANDY
Sequence: MKLCFFLLIFIRSFLLFKIKLVRTSEKKWRMGSRSHGDVKHPKSLPSLPVIGSLLHLGKKLPPHILFCNLQKKYGSLYSFMMGSHYVVVVNNHEDAREVLLKKGKTFGGRPRTVTTDILTRDGKDIAFADYSPTWKFHRKMVHSALCMFGEGTVAIEQIISREAASLCQTLTSFQRIPLDMAPELIRAVTNVVCSLCFNTRYKRGDAEFETMLKYSKGIVDTVAKDSLVDIFPWLQIFPNKDLDILRQSVAARDQLLQKKINEHKDAFCGETVKDLVDALLKAKLNMENNNSNVSQDVGLTEDHILMTVGDIFGAGVETTSTVLKWAVAYLLHYPEVQKKIQEELDVKVGFGRYPLLSDRKILHYTEAAISEVLRIRPVSPLLIPHVALKESSIGEYTIPKEARVVINLWSLHHDEKEWVNPHLFSPDRFLDENGNRVYSPSPSFLPFGAGIRVCLGEALAKMEVFLFLSWILQRFTLEVPEGDPLPDLEGKFGVVIQVKPFKVIAKLREVWKNIEIVT
What is the function of this protein?
Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione.  Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction.
What are the official names of this protein?
Steroid 17-alpha-hydroxylase/17,20 lyase, 17-alpha-hydroxyprogesterone aldolase, CYPXVII, Cytochrome P450 17A1, Cytochrome P450-C17, Cytochrome P450c17.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane.
Protein: GLGX_YERPS
Sequence: MAVLTHGSPTPSGAYFDGKGINFTLFSAHAEQVTLCLFDEQGQERQIAMPARTGDIWHGYLPGGKPGQRYGYRVSGPFDPSRGHRFNPHKLLIDPRTRALEGKVGDDPRFTGGVSQPDVRDSAAALPKCLVIHEEYDWQGDKPPAIPWGNTVIYEAHVRGLTQLHPDIPPELRGTYAALAHPALIEHLKTLGITTLELLPVQFHIDEPRLQKMGLSNYWGYNVLAPFAVDPDYASGREGISPLRELRDAVKALHNAGIEVILDVVFNHSAELDVFGPTLCQRGIDNASYYWLTPDGEYDNITGCGNALRLSHPYVTQWVIDCLNYWRDSCHVDGFRFDLGTVLGRTPAFDQHAPLFAALAADERLSACKLIAEPWDIGLGGYQLGNFPTGFSEWNDQYRDAMRGFWLRGEVPRGTFAQHFAASSRLFEQRGRLPSASINQITAHDGFTLLDLLCFNQKHNQMNGEENRDGSDNNHSNNFGCEGLVADAAIWQRRKACQRALLTTLLLSQGTPMLLAGDEQGHSQQGNNNAYCQNNILTWLDWGSADRALMTFTADLIRLRQQIPALTQDQWWQSGDSNVQWLDSQGQALSDAAWEQGCQQQLQILLSQRWLVLINATDHECEMHLPEGEWEGIPPFGVSDHAERLTTWRGSAHTICVLIKRD
What is the function of this protein?
Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin.
What are the official names of this protein?
Glycogen debranching enzyme, Limit dextrin alpha-1,6-maltotetraose-hydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: ACPS_SACEN
Sequence: MIVGIGTDLVGVVRFGESLERTPALAERVFTPAERRTRDGAARSVTSLAARFAAKEAAAKALGVPSGCRFTDCEVVQADDGRPSLRVSGRLARAAEVRGVTAWHVSLTHDAEMASAFVVAEA
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_PSEP1
Sequence: MRLRLIAVGSRMPKWVEEGWHEYAKRLPAELSLELVEIPLNTRGKNADVARLIRQEGEAMLSKVQPGERIVTLEVHGKPWSTEQLATELDRWRLDARTVNLMVGGPEGLAPEVCARAEQRWSLSPLTLPHPLVRILIGEQIYRAWTVLSGHPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCUP_RICAE
Sequence: MKQIINPLKGNNNKVPIWFMRQAGRYLPEYKKVRETTKNFLDFCYDVSKATEVTLQPIKRYGFDAAIIFSDILVLPHALGWEVDFKENIGPILKQFKSQEDFKYLQINPNYKLEKVYEIIKKVKKELPSPISLIGFAGSPWTVMSYMLEGKGKQDFKTSKKFIYENRILAEELLNFITEKTADHLINQAKSGADILKLFDSWSGVLAEEEFTEFVIEPTKKIILKVKEVFPKTPIIAFPKGAGLLYEKFIKEVPIDVLAVDQMVPLKKMKEWSDKVIVQGNLDPVVLLTNKEIIKEKTYKILQVMKGKNFIFNLGHGILPETPTENVEFLIEYVRLYEEKNSNSTF
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUT_EBVA8
Sequence: MEACPHIRYAFQNDKLLLQQASVGRLTLVNKTTILLRPMKTTTVDLGLYARPPEGHGLMLWGSTSRPVTSHVGIIDPGYTGELRLILQNQRRYNSTLRPSELKIHLAAFRYATPQMEEDKGPINHPQYPGDVGLDVSLPKDLALFPHQTVSVTLTVPPPSIPHHRPTIFGRSGLAMQGILVKPCRWRRGGVDVSLTNFSDQTVFLNKYRRFCQLVYLHKHHLTSFYSPHSDAGVLGPRSLFRWASCAFEEVPGLAMGDSGLSEALEGRQGRGFGSSGQ
What is the function of this protein?
Involved in nucleotide metabolism: produces dUMP, the immediate precursor of thymidine nucleotides and decreases the intracellular concentration of dUTP to avoid uracil incorporation into viral DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: TIM16_GIBZE
Sequence: MAHKFVVTAFLTGSRILGRSFVAAYKQAQAASAYQRAQVKAGNTTGGASLSSGMTLDEACKILNVKPPAGGQANVEEVLSRYKRLFDANDPQKGGSFYLQSKIVRAKERFEREIGPLREKMEAEAEIKEGFKPKVYKD
What is the function of this protein?
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.  In the complex, it is required to regulate activity of mtHSP70 (SSC1) via its interaction with PAM18/TIM14.  May act by positioning PAM18/TIM14 in juxtaposition to mtHSP70 at the translocon to maximize ATPase stimulation (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit TIM16, Presequence translocated-associated motor subunit PAM16.
What is the protein family that this protein belongs to?
Belongs to the TIM16/PAM16 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein.
Protein: SPT33_HUMAN
Sequence: MVTHAAGARTFCEEQKKGSTYSVPKSKEKLMEKHSQEARQADRESEKPVDSLHPGAGTAKHPPPAASLEEKPDVKQKSSRKKVVVPQIIITRASNETLVSCSSSGSDQQRTIREPEDWGPYRRHRNPSTADAYNSHLKE
What is the function of this protein?
Plays an important role in sperm motility and male fertility (By similarity).  Required for sperm midpiece flexibility and for the localization of sperm calcineurin to the mitochondria (By similarity).  Promotes mitophagy as well as acts as an autophagy mediator in male germline cells (By similarity).  Links damaged mitochondria to autophagosomes via its binding to the outer mitochondrial membrane protein VDAC2, as well as to key autophagy machinery component ATG16L1 (By similarity).
What are the official names of this protein?
Spermatogenesis-associated protein 33.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Cytoplasm. Mitochondrion.
Protein: YGLN_BACCE
Sequence: ASPINSHFTPYANYMPGYEDDVIMAAGTFIQGASIELSADGPIRPPYVAYVQGGLTYSHVKIAICSAIDALIEKELLTIS
What are the official names of this protein?
Uncharacterized protein in glnR 5'region.
What is the protein family that this protein belongs to?
To B.cereus similar ORF in glnR 5'region.
Protein: QUEA_BUCAT
Sequence: MQLSDFSFDLPKSLISFHPYFIRSTCRLMVMYGHTGMIFHKRFFNIIDEINSGDLIILNNTQVIPARFFGKKESGGKVEVLVEKILGINNILASIKNSKNINIGSKIFFGYKDKIKGSVVDCKNSFFEIFFHDNIDSAIDIINNIGEIPLPPYIKRFRNKLDVDLYQTVYKKKTGSIAAPTAGLHFDLPLLEALHNKGVDIDYITLHIGSGTFQPIRRVQIEEHIMHSESVEVSSSVIQKIKSCKKKGGRIIAVGTSTLRALESAYHSSEWSDSKDFISDTNIFIYPGYKHNIVDALITNFHFPESTLIMLVCSFLGYKNTMNAYNTAIVNKYSFFSYGDAMYITHNKLAPYENFII
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBSD_RHOBA
Sequence: MKRTRLLNSELSYEISRIGHTASITLCDAGLPIPSGVKRIDLAIEEGYPTFLRTLDAILSELKVEEIVIASEIHDHNQMLFEQMMKLFEAHRMAPKITEVSHVEFKQRTQASEAIVRTGECTPYANVILKSGVVF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PFKA_SALG2
Sequence: MIKKIGVLTSGGDAPGMNAAIRGVVRAALTEGLEVMGIYDGYLGLYEDRMVQLDRYSVSDMINRGGTFLGSARFPEFRDENIRAVAIENLKKRGIDALVVIGGDGSYMGAKRLTEIGFPCIGLPGTIDNDIKGTDYTIGYFTALGTVVEAIDRLRDTSSSHQRISIVEVMGRYCGDLTLAAAIAGGCEFIVVPEVEFNREDLVAEIKAGIAKGKKHAIVAITEHMCDVDELAHFIEKETGRETRATVLGHIQRGGSPVPYDRILASRMGAYAIDLLLEGHGGRCVGIQNEQLVHHDIIDAIENMKRPFKSDWMECAKKLY
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_HAEDU
Sequence: MIEADRIISASPQREEEVVDRAIRPKLLTDYVGQPSVREQMEIFIKAAKLRHEALDHLLIFGPPGLGKTTLANIVANEMGVNIRTTSGPVLEKAGDLAAMLTNLEPYDILFIDEIHRLSPAIEEVLYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLVGATTRAGSLTSPLRDRFGIVQRLEFYNVDDLTSIVKRSAACLNLNLSADGAYEVARRSRGTPRIANRLLRRVRDYADVRNNGVITSEIAKQALVMLDVDPQGFDFMDIKLLQAIVERFDGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFLQRTPRGRIATTRTYAHLGISLSE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: CTTB2_RAT
Sequence: MATDSASCEPDLSRAPGDAEGATAEAAKKEFDVDTLSKSELRMLLSVMEGELEARDLVIEALRARRKEVFIQERYGRFNLNDPFLALQRDYEAGAGDKEKPVCTNPLSILEAVMAHCRKMQERMSAQLAAAESRQKKLEMEKLQLQALEQEHKKLAAHLEEERGKNKHVVLMLVKECKQLSGKVVEEAQKLEEVMVKLEEEKKKTSELEDQLSAEKQRSAGMEAQLEKQLFEFDTEREQLRAKLTREEAHTTDLKEEIDKMKKMMEQMKKGNDGKPGLSLPRKTKDKRLASISVATEGPVTRSVACQTDVVTESTDPVKKLPLSVPIKPSTGSPLVSTNTKGNVGPSALLIRPGIDRQASHSDLGPSPPTALPSSASRIEENGPSAGNAPDLSNSTPSTPSGTAPAAAQTLGAAPQNHSQAPPVHSLHSPCANTHPGLNPRIQAARFRFQGNANDPDQNGNNTQSPPSRDVSPTSRDNLVAKQLARNTVTQALSRFTSPQAGASSRLGASPGGDAGTCPPVGRTGLKTPGAARVDRGNPPPIPPKKPGLSQTPSPPHPQLRASNAGAKVDNKIVASPPSTLPQGTKVVNEENVPKSSSPQLPPKPSIDLTVASAGCPVSALATSQVGAWPAETPGLNQPACTDSSLVIPTTVAFRSSINPVSASSRSPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRPTLLQQAAAQGNVTLLSMLLNEEGLDINYCCEDSHSALYSAAKNGHTDCVRLLLNAEARVDAADKNGFTPLCVAAAQGHFECIELLTAYNANINHSAAGGQTPLYLACKTGNKECIKLLLEAGTDRSIKTRDGWTPIHAAVDTGNVDSLKLLMYHRVPAPGNSLSAEEPKSGLFSLNGGESPPGSSKPVVPADLINHADKEGWTAAHIAASKGFKNCLEILCRHGGLEPERRDKCNRTVHDVATDDCKHLLENLNALKIPLRISVGEIQPSNDGSDDFECEHTICTLNIRKQTSWEDFSKAVSQALTNHFQAISSDGCWGLEDGTLNNTTDSCIGLGTSSIQSIMLGSIPWSTGQSFSQSPWDFMKKKKVEQVTVLLSGPQEGCLSSVTYTSMIPLQMLQNYLRLVEQYHNVIFHGPEGSLQDYIANQLALCMKHRQMAAGFPCEIVRAEVDSGFSKEQLVDVFISNACLIPVKQFPVKKKIIVILENLEKSSLSELLGDFLAPLENRSTESPCTFQKGNGTSECYYFHENCFLLGTLAKACLQGSDLLVQQHFRWVQLRWDCEPSQGLLQRFLRRKAVSKFRGQLPAPCDPVCKIVDWVISVWRQLNSCLARLGTPEALLGPKYFLSCPVVPGHAQATVKWMSKLWNAIIAPRVQEAILSRAAMNKQPGARQTASKKHPSQGQQAVVRAALSILLNKAILHGCPLPRTELDQQIADFKGGSFPLSIVSSYSKKKGESAAWRKVNTSPRKKPGHFSSPMWNKPDLKHEGMRNKSVPHLNINRSSSLSKQQSLENDLSMTLTLDHRLSLGSDDEADLVKELQSMCSSKSESDISKIADSREDLRTFDSSRTNPVTSAPVNLRMPVPQKEASPLSSHQTTECSNSKSKTELGVSRVKSFLPVPRSKVAQCSQNTKRSSSSSSNTRQLEINNNSKEENWNVDKHEHVEKRNK
What is the function of this protein?
Regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurons, and thus controls dendritic spinogenesis and dendritic spine maintenance.
What are the official names of this protein?
Cortactin-binding protein 2, CortBP2.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Cell projection, dendritic spine. Note=Remains associated with dendritic spines even after glutamate stimulation.