PharMolix/UniProtQA huggingface dataset:
Protein: MPTA_HALS3
Sequence: MSQQLPDVQATEPDVSVGLSEVGVTGVEKLVEIAREDDRPIVLMAEFEVYVDLPRGRKGIDMSRNMRVIDETLEDAVREPIYRVEEMCGEVAERLLEKHDYTTTATVEMNAELMLREETPASDLPTQGTIDIIASATAQEDAPTREEIGARVVGMTVCPCSQQMMSETARRKLAELGVGEDAVREFLRDVPQAGHSQRGHATLTVEAGGDPDVNLMDLVSVARDSMSARIYNTAKRPDEDHMTYESHANAKFVEDCVRSMARGVVEEFDHLPEDAVVTMKQSNDESIHQHNAHAERVAEFGQLREEVGSGE
What is the function of this protein?
Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
What are the official names of this protein?
GTP cyclohydrolase MptA, GTP cyclohydrolase IV.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: RS9_HAEIE
Sequence: MAENQNYGTGRRKSSSARVFIKPGSGKITINQRELDVYFGRETARMVVRQPLELVELTDKLDLYITVKGGGISGQAGAIRHGITRALMEYDETLRPALRAAGFVTRDARRVERKKVGLHKARRRPQYSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: DGKA_HUMAN
Sequence: MAKERGLISPSDFAQLQKYMEYSTKKVSDVLKLFEDGEMAKYVQGDAIGYEGFQQFLKIYLEVDNVPRHLSLALFQSFETGHCLNETNVTKDVVCLNDVSCYFSLLEGGRPEDKLEFTFKLYDTDRNGILDSSEVDKIILQMMRVAEYLDWDVSELRPILQEMMKEIDYDGSGSVSQAEWVRAGATTVPLLVLLGLEMTLKDDGQHMWRPKRFPRPVYCNLCESSIGLGKQGLSCNLCKYTVHDQCAMKALPCEVSTYAKSRKDIGVQSHVWVRGGCESGRCDRCQKKIRIYHSLTGLHCVWCHLEIHDDCLQAVGHECDCGLLRDHILPPSSIYPSVLASGPDRKNSKTSQKTMDDLNLSTSEALRIDPVPNTHPLLVFVNPKSGGKQGQRVLWKFQYILNPRQVFNLLKDGPEIGLRLFKDVPDSRILVCGGDGTVGWILETIDKANLPVLPPVAVLPLGTGNDLARCLRWGGGYEGQNLAKILKDLEMSKVVHMDRWSVEVIPQQTEEKSDPVPFQIINNYFSIGVDASIAHRFHIMREKYPEKFNSRMKNKLWYFEFATSESIFSTCKKLEESLTVEICGKPLDLSNLSLEGIAVLNIPSMHGGSNLWGDTRRPHGDIYGINQALGATAKVITDPDILKTCVPDLSDKRLEVVGLEGAIEMGQIYTKLKNAGRRLAKCSEITFHTTKTLPMQIDGEPWMQTPCTIKITHKNQMPMLMGPPPRSTNFFGFLS
What is the function of this protein?
Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids (PubMed:2175712, PubMed:15544348).  Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes (PubMed:2175712, PubMed:15544348).  Also plays an important role in the biosynthesis of complex lipids (Probable).  Can also phosphorylate 1-alkyl-2-acylglycerol in vitro as efficiently as diacylglycerol provided it contains an arachidonoyl group (PubMed:15544348).  Also involved in the production of alkyl-lysophosphatidic acid, another bioactive lipid, through the phosphorylation of 1-alkyl-2-acetyl glycerol (PubMed:22627129).
What are the official names of this protein?
Diacylglycerol kinase alpha, DAG kinase alpha, 80 kDa diacylglycerol kinase, Diglyceride kinase alpha, DGK-alpha.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic diacylglycerol kinase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: GPH_COLP3
Sequence: MKLQEKEVLLFDLDGTLVDSAPDLALAVNRTLKDLNKATFDQDTIHHWVGNGAKVLIERALSGSAIIDKELDETLTKDALTIFLAHYQQCLCIESVLYDDVQEGLLSLKAAGFRLAIITNKPAIFIQPILTGLGIDNLFELLIGGDTLADKKPHPAPLHYAMKQLNVVAEQCVMIGDSKNDILAAKAANIDSVGLTYGYNYGEDINQYGPQWCFDTFNELLISLKR
What is the function of this protein?
Specifically catalyzes the dephosphorylation of 2-phosphoglycolate.  Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.
What are the official names of this protein?
Phosphoglycolate phosphatase, PGP, PGPase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
Protein: RL17_AYWBP
Sequence: MPFSKLGRNKSQRRALLRTLMTDLIVQEKIMTTESKAKELQKLADKMVTLSKKNTLHTRRQAKRHLFDEKINDDTTVLQKLFKNISSKYLDRQGGYTRVIKTVPRRGDSAPMAIIAFV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: NOE2_RAT
Sequence: MSVPLLKIGAVLSTMAMVTNWMSQTLPSLVGLNSTVSRAGSSEKITLFQSPEEGWQLYTSAQAPDGKCICTAVIPAQSTCARDGRSRELRQLMEKVQNVSQSMEVLELRTYRDLQYVRSMETLMRSLDARLRTADGSVSAKSFQELKDRMTELLPLSSVLEQYKADTRTIVRLREEVRNLSGNLAAIQEEMGAYGYEDLQQRVMALEARLHACAQKLGCGKLTGVSNPITIRAMGSRFGSWMTDTMAPSADSRVWYMDGYYKGRRVLEFRTLGDFIKGQNFIQHLLPQPWAGTGHVVYNGSLFYNKYQSNVVVKYHFRSRSVLVQRSLPGAGYNNTFPYSWGGFSDMDFMVDESGLWAVYTTNQNAGNIVVSRLDPHTLEVVRSWDTGYPKRSAGEAFMICGVLYVTNSHLAGAKVYFAYFTNTSSYEYTDVPFHNQYSHISMLDYNPRERALYTWNNGHQVLYNVTLFHVISTAGDP
What is the function of this protein?
Involved in transforming growth factor beta (TGF-beta)-induced smooth muscle differentiation.  TGF-beta induces expression and nuclear translocation of OLFM2 where it binds to SRF, causing its dissociation from the transcriptional repressor HEY2/HERP1 and facilitating binding of SRF to target genes.  Plays a role in AMPAR complex organization.  Is a regulator of vascular smooth-muscle cell (SMC) phenotypic switching, that acts by promoting RUNX2 and inhibiting MYOCD binding to SRF.  SMC phenotypic switching is the process through which vascular SMCs undergo transition between a quiescent contractile phenotype and a proliferative synthetic phenotype in response to pathological stimuli.  SMC phenotypic plasticity is essential for vascular development and remodeling (PubMed:28062493).
What are the official names of this protein?
Noelin-2, Olfactomedin-2.
What are the subcellular locations of this protein?
Secreted. Synapse. Membrane. Nucleus. Cytoplasm. Note=Nuclear localization is induced by TGF-beta.
Protein: FRA1A_FRAAN
Sequence: MGVYTYENEFTSDIPAPKLFKAFVLDADNLIPKIAPQAVKCAEILEGDGGPGTIKKITFGEGSHYGYVKHKIHSIDKENHTYSYSLIEGDALSDNIEKIDYETKLVSAPHGGTVIKTTSKYHTKGDVEIKEEHVKAGKEKASHLFKLIEGYLKDHPSEYN
What is the function of this protein?
May be involved in ripening of fruits.
What are the official names of this protein?
Major strawberry allergen Fra a 1-A, Fra a 1.01A.
What is the protein family that this protein belongs to?
Belongs to the BetVI family.
Protein: COAD_AZOVD
Sequence: MNRVIYPGTFDPITKGHGDLVERAAKLFDHVIIAVAASPKKNPLFSLDKRVELAREVTRHLPNVEVLGFSSLLAQFAREQKANALLRGLRAVSDFEYEFQLANMNRQLAPEVESLFLTPSEKYSYISSTLVREIAALGGNIEQFVHPAVADALRERFRA
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_BACCR
Sequence: MLAKRIIPCLDVKEGRVVKGVNFIGLQDVGDPVEIAEAYNEAGADEIVFLDITATHEGRKTIIDVVEKTAAKVFIPLTVGGGISSVKDMYNLLRAGADKVSINSAAVRNPKLIEEGAEHFGSQCIVVAIDARKVAEGKWNVYVNGGRVDTGMDAIEWAKRVVKLGAGEILLTSMDADGTKSGYDLRLTEEISKSVSIPVIASGGCGHTDHIIEVFQKTTVDAALAASIFHYGEATVQSVKRKLRDANIEVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2444_RHIL3
Sequence: MNIVSNRQEQAFSNPLAMRAASRNGSWTRETSGAALGYVQANLAILPSALADDFLRFCVRNPKACPLVGISEKGSPRIPDLGVDLDIRTDVPRYRVWEDGELAAEPTDISDLWSDDLVVFAIGCSFSFEEALIANGIGLRHVAEGHNVAMYRTNIECVPAGPFSGPMVVSMRPLAPADAIRAVQITSRMPAVHGAPIHIGLPASIGIENLDQPDYGDPTRIMPDEMPVFWACGVTPQAVIQAARPKFAITHAPGCMLVTDKPNAALIAF
What are the official names of this protein?
Putative hydro-lyase RL2444.
What is the protein family that this protein belongs to?
Belongs to the D-glutamate cyclase family.
Protein: PSBC_SACHY
Sequence: MKILYSLRRFYHVETLFNGTFVLAGRDQETTGFAWWAGNARLINLSGKLLGAHVAHAGLIVFWAGAMNLFEVAHFVPEKPMYEQGLILLPHLATLGWGVGPGGEVLDTFPYFVSGVLHLISSAVLGFGGIYHALLGPETLEESFPFFGYVWKDRNKMTTILGIHLILLGLGAFLLVLKALYFGGVYDTWAPGGGDVRKITNLTLSPGVIFGYLLKSPFGGEGWIVSVDDLEDIIGGHVWLGSICVLGGIWHILTKPFAWARRAFVWSGEAYLSYSLAALSVFGFIACCFVWFNNTAYPSEFYGPTGPEASQAQAFTFLVRDQRLGANVGSAQGPTGLGKYLMRSPTGEVIFGGETMRFWDLRAPWLEPLRGPNGLDLSRLKKDIQPWQERRSAEYMTHAPLGSLNSVGGVATEINAVNYVSPRSWLATSHFVLGFFFFVGHLWHAGRARAAAAGFEKGIDRDLEPVLYMTPLN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP43 reaction center protein, PSII 43 kDa protein, Protein CP-43.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: MOAC_BACCN
Sequence: MSSFTHFNDQGRAKMVDISDKKVTVRTAIACSSILVTKEIYDKISHHEIGKGDVLGVAQIAGIMAAKRTSDVIPMCHPLLLKGVDVSFDWKQEKKQYRLLIEVKVKTEGSTGVEMEALTAASMTALTVYDMCKAVDKGMIIGETYLLEKTGGKSGDYLRNS
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: ATPH_SORBI
Sequence: MNPLIAAASVIAAGLAVGLASIGPGVGQGTAAGQAVEGIARQPEAEGKIRGTLLLSLAFMEALTIYGLVVALALLFANPFV
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, chloroplastic, ATP synthase F(0) sector subunit c, ATPase subunit III, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PKS17_DICDI
Sequence: MTFNNIKDENNDDIAIIGMGFRFPGGGNNPYQFWNQLSNKMDGISKIPTEKWSRSFYEQKYINNEYGGVLKDEEWKNFDPLFFGISPKEAPIIDPQQRLLMTTLWEAFEDANIKPSTFRGSDTAVFIGMMNTDYQRCQFRDISYVNPYITPGTAGSFISNRLSFSFDLRGPSMTLDTACSSSLNAVYLGCQAIANGDSKMAIVGGVNGIFDPCFSMTFSGLNMLGHKGQCRSFDAGADGYIRSEGGGVCILKKYSDAIKDGDRIYCVIKGGSSNVDGYNAKTNIIQPSMKAQGENIEIALKKSGVNPSDIYYIEAHGTGTPVGDPIEIEAISRIFKDNHTPDAPLYIGSVKSNIGHLESAAGIASLIKVALSLKNRSLVPNIHFEKPNPLIKFEDWNIRVVTDEIQFPINKLINMGINCFGLSGSNCHMILSEAPINYDELLKTTNNNSTSSSSNDDKKEYLIPFSANCNISLDKYIEKLISNQSIYKDTILFKDFVKHQTISKSNLIKRKVITASDWDDFLNKRNETTSTSSLTSTISAPASSTPVIYVFTGQGPQWRDMGKALYETESVFKDAIDHCDKLLANYFGYSILQKLLSLESEDSPEIHHPILAQPSIFLIQVGLVALYKSFGISPSIVVGHSFGEIPSALFSDVISLETAVKIVYYRGLAQNLTMGTGRLLSIGIGADAYLEKCALLYPEIEIACYNDPNSIVITGSEQDLLGAKSTLSAEGVFCAFLGTPCSFHSSKQEMIKEKIFKDLSDLPESNVPCVPFFSTITGSQLSHKGFYNVQYIYDNLRMPVEFTKAISNIFNFIEENESYKNAIFLEIGPHPTLGFYIPKCKPSNSTITSKPIIVSPLHKKKEELTQFKLAISTLYCNGVEIDFASGQQLLPTSSSSGGGDISSFKESTNKLPRYQWDFEEYWDEPNQSKMVKRGPSNNLLGHDQFAGNTLMELFIDIDKSAHQYLKGHKIKGKYLFPGSGYIDNILRQFNGQDITIFNLEFSNPFFLKDGVQHHLQTSITPTTKGEFKVEFFIKDNRNSTKWTKTSNGRIGLFKHNPKNNKLDIEKLKSQCSFTTLTKSEVYNKLLLLSLPYGPTFQRVESCSIGDGCSFFKLSMSPCSEFDKDFLNPSIIDCAFHGLLVLSEGPQEIVFDRLQDMKFYSSNVPSTRPQFIYAFAKFDKIEGNSTHGSLNIILEDGTLLISIKNVKCTSLIRLKKQSIKYPSQNVYSHHWQSKDSPLTLIENQLIEEKSSESKINFEKLLNDKLFNYYLIRLLNQSIKSEFIEFDYKTSTVDTLDIGSKNAKLLEKIQSILNPIDSLDQSIDITSLKQAIIVKSSFKNEIKLVEKSIKRIVSLLKGGESEHFSPSNPSSPNDTPRNNSNNCSSKNNAASSDDADDDTNNEETINQLNNEPFNFSNSQFISNQNQLISKTIVNSFDRLINSIEIGEKKLIKIIDLSSIYQNYQLSKLLLLQLNQLLINLSNNNNIEIEYTIPSNTKNIDSITEETKSISNVLNIKYRSFDLQDDLESNGYLNSNYDLIITSLLLVSTNSIDSNEVLSKLYKLLLPKGQLILMEPPKGVLSFNLLFANDFKQSLEIKSEQEIKSLIIYCGFTKIETNLNTKDDEEQQQPPPPSILIVQAEKRDIESMSLTFSSDPKSLNSSYSNCIFIVSKEQKENPTSYIQEYFDITEFFCQNATIIEADDSELLTKTIESGVGKNDIIFFLVSLEELTIENYKQVTMQYTLVNQILLRNNLSTRFALLTYDSQNGGKNYLGSSLIGTFRYFLEFRSLNIFSIDVDKDSIDNLTLFLRLVDLSTIGDRETIVRNNKIFVQKIFKEPKLLSPSNNYEKNTNNLFLYSNSNLDFSFQSKEKLLHGCVEIKVMSTGINYKDSLFYRGLLPQEVFSKGDIYSPPFGLECAGYITRVAPSGVTRFKVGDQVVGFASHSLSSHVTTHQNKIVLKPENISFNEAAAVCVVYATSYYSIFHIGAFIADKESILVHSATGGVGLASLNLLKWKRNQLKKHGNSEISNDASIYATVGSKEKIDYLQEKYGDLITAIYNSRDTEYCDEIKQQSAQGGVDLILNTLSGDYLSSNFRSLSQVGRIMDLSVTQLVENDSLDFSNFKYHVGYNTIDLDRATKYNSKIIRDILTEVFDAISDGSLENIPVKVFPAIQVKTAIEYINERVHIGKIVVDFENFEQDILKPALQEKENPIQLNKVKKLEHTCDTLNNTILITGQTGIAVHILKWIISGSVLNSNKSQQQVTDFIILSRSSLKWELENLINQTKHKYGDRFRFHYKSVNIADLNSTRTAIDQVYSSCKNVSPIKSVLHFATVYEYILPENITQTVIDNTHNPKAVGAINLHNLSIEKDWKLENFILFSSIGAIIGGSKQCAYSSANLVLDSLSNYRKSIGLASTSINWGGLDAGGVAATDKSVASFLEGQGILLVSLSKILGCLDSVFQPSNSHLSNFMLSSFNIDNLLSSAPQMKRKMDHHLTNYKTSSASSDDSLGDSGSTQAKVISTISELLSIHPSKLNLDTRLKDYGIDSLLTVQLKNWIDKEFTKNLFTHLQLSSSSINSIIQRISSKSTSTSTPNPTNTSKQTATKKT
What is the function of this protein?
Probable polyketide synthase.
What are the official names of this protein?
Probable polyketide synthase 17, dipks17.
Protein: DCL1_ORYSJ
Sequence: MAGGGGVGGGAGEHAAAAYWYDACEDGASLLCGIDFAASADFDPGLIPAMDTGADDGFVAEIDRILESINAESSPAPPPPPPPPLPEPVPVAPPELPIQEKQLQVASAPVANNAVAVVGVVQRSKGVVARKEPRRESHGCAANGGGGGEWRDGKRPRLASGGVGGPRQEWRRRPMLPPPPSRGWDDRRGRRDFDRVRKHEHHRREARGFWERDRGGKMVFRSGTWEQESDREAKRARTQDGGSMEKKAEADRMGAAQREKPVAEERARQYQLEVLEQAKSRNTIAFLETGAGKTLIAVLLIKSVCDKMLKENKKMLAVFLVPKVPLVYQVLVMTAQILLNILRHSIIKMDAIHLLILDECHHAVKKHPYSLVMSEFYHTTPKEKRPAVFGMTASPVNLKGVTSQEDCAIKIRNLESKLDSVVCTIKDRKELEKHVPMPLEVVVQYDKAATLWSLHEQIKQMESTVEEAALSSSKRTKWQFMGARDAGSRDELRLVYGVSERTESDGAANLIQKLRAINYALGELGQWCAYKVAQSFLTALQNDERANYQVDVKFQESYLKKVVDLLHCQLTEGAAMKSETSDVEMQNTEKHNTNDLEEGELPDSHGEHVDEVIGAAVADGKVTPRVQALIKILLKYQHTEDFRAIIFVERVVTALVLPKVLAELPSLSFIRCASLIGHNNNQEMRACQMQDTISKFRDGRVTLLVATSVAEEGLDIRQCNVVIRFDLAKTVLAYIQSRGRARKPGSDYILMLERGNISHETFLRNARNSEETLRKEAMERTDLSHLDGTSVLSPVDTSPGSMYQVESTGAVVSLNSAVGLIHFYCSQLPSDRYSILHPEFIMQKYEKPGGSVEYSCKLQLPCNAPFEKLEGPICSSIRLAQQAVCLAACKKLHEMGAFTDTLLPDRGSGEGEKTEQNDEGEPLPGTARHREFYPEGVADILRGEWILSGRDGYQNSQFIKLYMYSVNCVNVGTSKDPFVTQLSNFAIIFGNELDAEVLSTTMDLFVARTMITKASLVFRGRIEITESQLVLLKSFHVRLMSIVLDVDVDPSTTPWDPAKAYLFVPVGAEKCTDPLREIDWTLVNNIVNTDAWNNPLQRARPDVYLGTNERTLGGDRREYGFGKLRHGTAFGQKAHPTYGIRGAIAEFDIVKASGLVPARDRGHFSDYQNQGKLFMADSCWNAKDLAGMVVTAAHSGKRFYVDCICYNMNAENSFPRKEGYLGPLEYSSYADYYKQKYGVELIYRKQPLIRARGVSYCKNLLSPRFEHSDAREGDFSENLDKTYYVYLPPELCLVHPLPGSLVRGAQRLPSIMRRVESMLLAVQLKDIIDYPVPATKILEALTAASCQETLCYERAELLGDAYLKWVVSRFLFLKYPQKHEGQLTRMRQQMVSNMVLYQYALNKTLQSYIQADRFAPSRWAAPGVLPVFDEESREYEPSIFDEESTGCELQKESYDDYADNMQEDGEIEGDSSCYRVLSSKTLADVVEALIGVYYVAGGKIAANHLMKWIGIHAELDPEEIPPPKPYDIPESIMRSINFDTLKGVLGIEFQNKGLLVEAITHASRPSSGVSCYQRLEFVGDAVLDHLITRHLFFTYTDLPPGRLTDLRAAAVNNENFARVAVKHKLHVHLRHGSSALETQIREFVKDVQEELLKPGFNSFGLGDCKAPKVLGDIVESIAGAIFLDSGYDTSVVWKVFQPLLHPMVTPETLPMHPVRELQERCQQQAEGLEYKASRAGNIATVEVFVDGVQIGVAQNPQKKMAQKLAARNALVVLKEKETATKKEDERDGEKKNGAQMFTRQTLNDICLRRQWPMPQYRCVNEGGPAHAKRFVYSVRVNTSDRGWTDECIGEPMPSVKKAKDSAAVLLLELLNRDFPDKPDGKQP
What is the function of this protein?
Involved in the RNA silencing pathway.  Cleaves double-stranded RNA to produce microRNAs (miRNAs) of 21-24 nucleotides which target the selective destruction of complementary RNAs.  Regulates by this way the development of the plant.  May not be involved in small interfering RNAs (siRNAs) production.
What are the official names of this protein?
Endoribonuclease Dicer homolog 1, Dicer-like protein 1, OsDCL1.
What is the protein family that this protein belongs to?
Belongs to the helicase family. Dicer subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PHCA_PORPP
Sequence: MKTPITEAIATADNQGRFLSNTELQAVNGRYQRATASLTAAKALTGSAQRLITGAAQAVYNKFPYTTQMPGPAYASSAIGKAKCARDIGYYLRMVTYTLVVGGTGPMDEYLVAGLEEINRSFDLSPSWYIEALQYIKNSHGLSGQVANEANAYIDYAINTSL
What is the function of this protein?
Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex (phycobilisome, PBS).  Phycocyanin is the major phycobiliprotein in the PBS rod.
What are the official names of this protein?
R-phycocyanin-1 subunit alpha, R-phycocyanin I alpha chain.
What is the protein family that this protein belongs to?
Belongs to the phycobiliprotein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side. Note=Part of the phycobilisome rod.
Protein: RL23_CALMQ
Sequence: MSTQPIITRFVLTEKAIRLAEKENTLTIVVPRSVNKKVIKDYVEKAYKVKVIDVRTLITMEGEKKAYVRLSSENNAIELLTNLGLL
What is the function of this protein?
Binds to 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: IF2_STAS1
Sequence: MSKKRIYEYAKDLKIKSKEIIHELKKMDVEVTSHMQTLEDDQIKALDKIYKPEKAEQSEKSQQKNTQNKQQTTHNKGNQSNKGNQNNKPNNKKNNKNNKNNKNNKNNKQPKQEEPKEMPSKITYQDGITVGELAEKLNVDSSGIIKKLFLLGIMANINQSLDDETLELIVDDYGVEIEKEIVVDEEDLAIYFDDETEDENAIERPAVVTIMGHVDHGKTTLLDSIRHTKVTAGEAGGITQHIGAYQIENDGKKITFLDTPGHAAFTTMRARGAQVTDITILVVAADDGVMPQTIEAINHAKEAEVPTIVAVNKIDKPTSNPDRVMQELTEYGLIPEDWGGDTIFVPLSALSGDGIEDLLEMIVLTSEVQELKANPEKNAVGTVIEAELDKSRGPSASLLVQNGTLNVGDSLVVGNTYGRIRAMVNDLGQRIKTAGPSTPVEITGINDVPQAGDRFVVFKDEKQARRIGEARHEANVMQQRQESKSVSLDNLFEQMKQGEMKDLNVIIKGDVQGSVEALAASLMKIDVEGVNVRIIHTAVGAINESDVTLANASNGIIIGFNVRPDTGAKRAADNEGVDMRLHRVIYNVIEEIESAMKGMLDPEFEEQVIGQAEVRQTFKVSKVGTIAGSYVIDGKITRNAGVRVIRDGIVQFEGELDTLKRFKDDAKEVAQGYECGITIEKYNDLKEGDIIEAFEMVEIKR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRB_XYLF2
Sequence: MNVTFDLTPPSPSQREALIATLNAEERRILLQHGTEAPFCNRLLDNNQLGTYTCRLCGLPLFHSNAKFKSGTGWPSFFEPYTHTHIRKQHDTSHGMIRTEILCARCNSHLGHLFPDGPPPTYERYCLNSVSLTFIPTGTLLPDQLHRGDNTTYRT
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: CALR_CAEEL
Sequence: MKSLCLLAIVAVVSAEVYFKEEFNDASWEKRWVQSKHKDDFGAFKLSAGKFFDVESRDQGIQTSQDAKFYSRAAKFDKDFSNKGKTLVIQYTVKHEQGIDCGGGYVKVMRADADLGDFHGETPYNVMFGPDICGPTRRVHVILNYKGENKLIKKEITCKSDELTHLYTLILNSDNTYEVKIDGESAQTGSLEEDWDLLPAKKIKDPDAKKPEDWDEREYIDDAEDAKPEDWEKPEHIPDPDAKKPEDWDDEMDGEWEPPMIDNPEYKGEWKPKQIKNPAYKGKWIHPEIENPEYTPDDELYSYESWGAIGFDLWQVKSGTIFDNIIITDSVEEAEAHAAETFDKLKTVEKEKKEKADEETRKAEEEARKKAEEEKEAKKDDDEEEKEEEEGHDEL
What is the function of this protein?
Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle (By similarity).  This lectin may interact transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER (By similarity).  Probably by controlling the folding of extracellular matrix protein unc-52/Perlecan, may play a role in the formation of fibrous organelles, a hemidesmosome-like structure attaching muscles to the epidermis (PubMed:20153198).  Protects dopaminergic neurons against oxidative stress-induced neurodegeneration (PubMed:29346364).  May play a role in protection against ER stress (PubMed:24933177).  Plays a role in modulating lifespan, acting by influencing ER calcium homeostasis (PubMed:32905769).
What are the official names of this protein?
Calreticulin.
What is the protein family that this protein belongs to?
Belongs to the calreticulin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: DTX3_HUMAN
Sequence: MSFVLSRMAACGGTCKNKVTVSKPVWDFLSKETPARLARLREEHRVSILIDGETSDIYVLQLSPQGPPPAPPNGLYLARKALKGLLKEAEKELKKAQRQGELMGCLALGGGGEHPEMHRAGPPPLRAAPLLPPGARGLPPPPPPLPPPLPPRLREEAEEQESTCPICLGEIQNAKTLEKCRHSFCEGCITRALQVKKACPMCGRFYGQLVGNQPQNGRMLVSKDATLLLPSYEKYGTIVIQYVFPPGVQGAEHPNPGVRYPGTTRVAYLPDCPEGNKVLTLFRKAFDQRLTFTIGTSMTTGRPNVITWNDIHHKTSCTGGPQLFGYPDPTYLTRVQEELRAKGITDD
What is the function of this protein?
Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations.  Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context (By similarity).  Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
What are the official names of this protein?
Probable E3 ubiquitin-protein ligase DTX3, Protein deltex-3, Deltex3, RING finger protein 154, RING-type E3 ubiquitin transferase DTX3.
What is the protein family that this protein belongs to?
Belongs to the Deltex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU_CAMLR
Sequence: MAKEKFSRNKPHVNIGTIGHVDHGKTTLTAAISAVLSRRGLAELKDYDNIDNAPEEKERGITIATSHIEYETENRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLSRQVGVPYIVVFMNKADMVDDAELLELVEMEIRELLSSYDFPGDDTPIISGSALQALEEAKAGQDGEWSKKILDLMAAVDDYIPTPARDTDKDFLMPIEDVFSISGRGTVVTGRIEKGVVKVGDTIEIVGIRDTQTTTVTGVEMFRKEMDQGEAGDNVGVLLRGTKKEDVERGMVLAKPKSITPHTDFEAEVYILNKDEGGRHTPFFNNYRPQFYVRTTDVTGAIKLAEGVEMVMPGDNVRITVSLIAPVALEEGTRFAIREGGRTVGSGVVSKIIK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_GRABC
Sequence: MSSPQKTSLAARRRAERMSREAMYEVIRSPLITEKATLLSERSQVVFRVAIDATKPEIKAAVEGLFGVKVIGVNTLVNKGKTKRFRGRPGQRSDVKKAYVQLVAGQAIDLTAKLA
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.