PharMolix/UniProtQA huggingface dataset:
Protein: FUCO_DROME
Sequence: MAISAWMPLLVALIVVWISAAEVDAQVPGPRTRYQPNWASLDQRPLPQWYDDAKVGIFLHYGVYSVPSFGSEWFWTNWKNLRNPEYVQFMQRNYKPDFTYQEFASQFTAELFNATKWALLFKDSGARYVVLTSKHHDGFTLWPSKNSYGWNSMDVGPKRDIVKELAAAIRKESDLRFGLYYSLFEWFNPLWTDDKLHLLMQQHFVERKVRPEQMELVQQYLPEIIWSDGDWEAPAKYWRSEEFIAWLYNDSPVRDTVVTNDRWGFGTACMHGDFYNCADRFNPGVLQAHKWENAFTLDRTSWGQRFDVSLSDFMTSKEVIKEIITTVSCNGNVLINVGPTKFGTILPIFEERLRDMGRWLKFNGEGIYGSVPWIYQNDTINGNVWYTRQKEASNGKITIYAFVLEYPYDTNELDIYPLGKDINIFRNVMLTGIDMGTGGDILNEQSTEVVMLGMEDTKIKWNADHNRLHIVFPPKNHIDKRGLDYAWTFKITIT
What is the function of this protein?
Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
What are the official names of this protein?
Putative alpha-L-fucosidase, Alpha-L-fucoside fucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 29 family.
Protein: PAEA_ECOL6
Sequence: MLNSILVILCLIAVSAFFSMSEISLAASRKIKLKLLADEGNINAQRVLNMQENPGMFFTVVQIGLNAVAILGGIVGDAAFSPAFHSLFSRYMSAELSEQLSFILSFSLVTGMFILFADLTPKRIGMIAPEAVALRIINPMRFCLYVCTPLVWFFNGLANIIFRIFKLPMVRKDDITSDDIYAVVEAGALAGVLRKQEHELIENVFELESRTVPSSMTPRENVIWFDLHEDEQSLKNKVAEHPHSKFLVCNEDIDHIIGYVDSKDLLNRVLANQSLALNSGVQIRNTLIVPDTLTLSEALESFKTAGEDFAVIMNEYALVVGIITLNDVMTTLMGDLVGQGLEEQIVARDENSWLIDGGTPIDDVMRVLDIDEFPQSGNYETIGGFMMFMLRKIPKRTDSVKFAGYKFEVVDIDNYRIDQLLVTRIDSKATALSPKLPDAKDKEESVA
What is the function of this protein?
Involved in cadaverine and putrescine tolerance in stationary phase.  May facilitate the efflux of both cadaverine and putrescine from the cytoplasm, reducing potentially toxic levels under certain stress conditions.
What are the official names of this protein?
Polyamine export protein.
What is the protein family that this protein belongs to?
Belongs to the UPF0053 family. PaeA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PTH_SHEPC
Sequence: MSEIKLIVGLANPGAEYAQTRHNAGAWYVQELARICGVTLVPDSKYFGLTARAVLQGKDVRLLIPTTYMNLSGKAVGALANFFRITPEEILVAHDELDMPPGVAKFKLGGGHGGHNGLKDIIAKLANDKNFYRLRIGIGHPGDKNQVSGYVLGKAPAKEQELIEAAIDEAVRSTEILYKENMVKAMTRLHSFKAE
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLY_ACTPJ
Sequence: MALWGGRFKQEADAKFKFFNDSLRFDYRLALQDIDGSIGWAKAITSVGILTEQEHQQLVVALKELRAEIEPNIAIILRDDAEDIHSWVESKLIEKVGDLGKKLHTGRSRNDQVAVDMKMWCKVQAVVLQERIRNLQHKLVETAEANQNAVMPGYTHLQRAQPITFAHWCMAYYEMLERDFSRLTDAYKRMHTCPLGSGALAGTAYSIDRDALAQDLGFAIGTRNSLDSVSDRDHVLELLSTASISMVHLSRFAEDLIFFNSGESAFLELSDRVTSGSSLMPQKKNPDACELIRGKSGRVFGALSGLLTTLKGLPLAYNKDMQEDKEGIFDAMETWQACLEIGALVLEDINVNVERTREAAQQGYSNATELADYLVAKGIPFREAHHIVGEAVVYAISKREPLEALSVAEFKQFHPVIDEDVYPILSLESCLEKRSAKGGVNPERVREAIEAAKVNLGA
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_ENTFA
Sequence: MSQKETFYITTPIYYPSGKLHIGNSYTTIACDAMARYKRLMGFDVFYLTGVDEHGQKIEKKAAELNVTPKEYVDKMAADVQKLWKTLDISYDKFIRTTDDYHMAAVQQIFDRLVEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYRDDEGNVIGGKAPSGHEVELVKEESYFFRMSKYADRLVQYYEEHPEFIQPESRKNEMLNNFIKPGLEDLAVSRTTFSWGIPLKNDPKHVVYVWIDALSNYITALGYGSEDDSLFQKYWPANVQMVGKEIVRFHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRYYLLRAIPFGSDGVFTPEDFVSRLNYDLANDLGNLLNRTIAMINKYCDGKVPAYASKVTPFDSELSTTAANVIGKYHEAMEKMEFNTAIAEIWTLVSRANKYIDETAPWVLAKEEEKRNELESVMIHLAESLRIVAILLQPVMTETPGKIFEQLGLDPETMNMENIHFGEFPTDVTVTSKGTPIFPRLEIETEVTYIQKKMSQSESATEEDIKWNPEETTLVSTKEKQIKYDDFDKVELKVAEVIDCKKVKGADKLLQFRLDAGDENHRQILSGIAEFYPDPAALIGKKVVIVANLKPRKMRGQISQGMILSAESPEGKLQIVEAPKEMPNGAGIA
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECCC3_MYCTO
Sequence: MSRLIFEARRRLAPPSSHQGTIIIEAPPELPRVIPPSLLRRALPYLIGILIVGMIVALVATGMRVISPQTLFFPFVLLLAATALYRGNDKKMRTEEVDAERADYLRYLSVVRDNIRAQAAEQRASALWSHPDPTALASVPGSRRQWERDPHDPDFLVLRAGRHTVPLATTLRVNDTADEIDLEPVSHSALRSLLDTQRSIGDVPTGIDLTKVSRITVLGERAQVRAVLRAWIAQAVTWHDPTVLGVALAARDLEGRDWNWLKWLPHVDIPGRLDALGPARNLSTDPDELIALLGPVLADRPAFTGQPTDALRHLLIVVDDPDYDLGASPLAVGRAGVTVVHCSASAPHREQYSDPEKPILRVAHGAIERWQTGGWQPYIDAADQFSADEAAHLARRLSRWDSNPTHAGLRSAATRGASFTTLLGIEDASRLDVPALWAPRRRDEELRVPIGVTGTGEPLMFDLKDEAEGGMGPHGLMIGMTGSGKSQTLMSILLSLLTTHSAERLIVIYADFKGEAGADSFRDFPQVVAVISNMAEKKSLADRFADTLRGEVARREMLLREAGRKVQGSAFNSVLEYENAIAAGHSLPPIPTLFVVADEFTLMLADHPEYAELFDYVARKGRSFRIHILFASQTLDVGKIKDIDKNTAYRIGLKVASPSVSRQIIGVEDAYHIESGKEHKGVGFLVPAPGATPIRFRSTYVDGIYEPPQTAKAVVVQSVPEPKLFTAAAVEPDPGTVIADTDEQEPADPPRKLIATIGEQLARYGPRAPQLWLPPLDETIPLSAALARAGVGPRQWRWPLGEIDRPFEMRRDPLVFDARSSAGNMVIHGGPKSGKSTALQTFILSAASLHSPHEVSFYCLDYGGGQLRALQDLAHVGSVASALEPERIRRTFGELEQLLLSRQQREVFRDRGANGSTPDDGFGEVFLVIDNLYGFGRDNTDQFNTRNPLLARVTELVNVGLAYGIHVIITTPSWLEVPLAMRDGLGLRLELRLHDARDSNVRVVGALRRPADAVPHDQPGRGLTMAAEHFLFAAPELDAQTNPVAAINARYPGMAAPPVRLLPTNLAPHAVGELYRGPDQLVIGQREEDLAPVILDLAANPLLMVFGDARSGKTTLLRHIIRTVREHSTADRVAFTVLDRRLHLVDEPLFPDNEYTANIDRIIPAMLGLANLIEARRPPAGMSAAELSRWTFAGHTHYLIIDDVDQVPDSPAMTGPYIGQRPWTPLIGLLAQAGDLGLRVIVTGRATGSAHLLMTSPLLRRFNDLQATTLMLAGNPADSGKIRGERFARLPAGRAILLTDSDSPTYVQLINPLVDAAAVSGETQQKGSQS
What is the function of this protein?
Part of the ESX-3 specialized secretion system, which is important for iron and zinc uptake or homeostasis.
What are the official names of this protein?
ESX-3 secretion system protein EccC3, ESX conserved component C3, Type VII secretion system protein EccC3, T7SS protein EccC3.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NPY_CARAU
Sequence: MHPNMKMWTGWAACAFLLFVCLGTLTEGYPTKPDNPGEGAPAEELAKYYSALRHYINLITRQRYGKRSSADTLISDLLIGETESHPQTRYEDQLVW
What is the function of this protein?
NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.
What are the official names of this protein?
Pro-neuropeptide Y.
What is the protein family that this protein belongs to?
Belongs to the NPY family.
What are the subcellular locations of this protein?
Secreted.
Protein: PP1A_HUMAN
Sequence: MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK
What is the function of this protein?
(Microbial infection) Necessary for alphaviruses replication.
What are the official names of this protein?
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, PP-1A.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus, nucleoplasm. Nucleus, nucleolus. Note=Primarily nuclear and largely excluded from the nucleolus. Highly mobile in cells and can be relocalized through interaction with targeting subunits. NOM1 plays a role in targeting this protein to the nucleolus. In the presence of PPP1R8 relocalizes from the nucleus to nuclear speckles. Shuttles toward the cytosol during infection with VEEV (PubMed:29769351).
Protein: DNLJ_PELPB
Sequence: MTDIIRAAEAIAQLRREIERHTHLYYVEAKPELSDFEFDQLLDQLITLERQFPQLLTPDSPSQRVGGAITREFPAVQHREPMLSLSNSYSITEVEEFYNRVRKLLALEGVVEQEMVAELKFDGVAISLIYQDGILVRGATRGDGRQGDDITANLKTVATIPLRLEETLVAALQGEERAIEVRGEVFMRKEDFERLNESRPDEDRFANPRNATAGSLKLQDSGEVARRSMSFVAYYLKGLKDESTPHIHRLELLARLGFFTGDHYRLCNTLEEINTYIAEWAEKRWQLPYETDGVVLKLNDVPFREKLGATAKSPRWAIAYKYPAQQARSVLQNVLFQVGRLGTITPVAELEPVLLAGSTVSRSTLHNFDEIERLGLMLRDRVIIEKSGEVIPKVVRTLFEERPADAMPILPPTHCPSCGAPLVRPENEVSYSCPNEEECPAQIKGRLLHFASRNAMDIQTLGDALVEQLVAKGLVKDPGDLYFLQEPQLEKLERMGPKSAQNILRALEKSREKSYERLLYALGIRHVGRATARELSQACPSIDLLREASEEQLATIPDIGPVVARSIIDYFAKPSWPHLLEKLRTAALQLSASEPKEQVNRNFEGVTVLFTGSLERYDRQKASELVLERGGRVVGSVSKKTGMVVAGQDPGSKLQKANKLGVRVVSEDEFEAML
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: PYRH_RICAH
Sequence: MISNINALKYKKVLLKVSGEALMGDKQFGHEYEVIKKISSDIKEVIDLGVEVAIVVGGGNIYRGINAALVGMDRASADYIGMLATVINALTLQNVMESLDIYTRVLSAIPMMSVCEPYIRRKAKRHMEKKRVVIFAGGTGNPFCTTDSAAVLRAIEMNCDMLLKATQVDGVYDADPKKNPDAKKYCTINYKDVITNNLQVMDTAAIAVARENKLPIRIFSIKEQGNFARVIQDKGEYTTIEESVV
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_HAEIN
Sequence: MIDPNLLRNNLAEVAEKLKVKRNFMLDTEKLTALEDQRKNLQVTTENLQAERNARSKAIGAAKARGEDIAPLLAEMDDMGNQLTEAKAQLDAVLAEINQIALSIPNLPADEVPLGKDDTENKEILRWGTPRTFDFEVKDHITLGEEANGLDFAAGAKLAGARFAVMKGQIAKMHRALAQFMLDLHTEQHGYLETYVPYLVNHATLYGTGQLPKFGEDLFHTLALEGEQPYALIPTAEVPVTNLVRDVIIDEAELPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVDPDKSMEALEELTGHAEKVLQLLNLPYRKVLLCTGDMGFGSCKTYDLEVWVPAQNTYREISSCSNMWDFQARRMQARCKAKGDKKTRLVHTLNGSGLAVGRTLVAVLENYQNADGSITVPEELRPYMGGLDVIGK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: A1KC_LOXAR
Sequence: MGHMVNAIAQIDEFVNLGANSIETDVSFDSSANPEYTYHGVPCDCRRWCKKWEYFNNFLKALRKATTPGDSKYHEKLVLVVFDLKTGSLYDNQASDAGKKLAKSLLQNYWNNGNNGGRAYIVLSIPNLAHYKLIAGFKEALTSEGHPELMDKVGYDFSGNDDIGDVANAYKEAGVTGHVWQSDGITNCLLRGLDRVRKAVANRDSSNGYVNKVYYWTVDKRQSTRDALDAGVDGIMTNYPDVIADVLNESAYKAKFRIASYDDNPWETFKN
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LarSicTox-alphaIB1c, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ARL5_CAEEL
Sequence: MGLIMAKLFQSWWIGKKYKIIVVGLDNAGKTTILYNYVTKDQVETKPTIGSNVEEVSYRNLDFVIWDIGGQESLRKSWSTYYVQTDVVIVVIDSSDTTRIPIMKEQLHNMLQHEDLARAHILVLANKQDLPGAMNPAEVSTQLGLQTLRGARKWQINGCCAVKGEGLPEALEWIANNL
What is the function of this protein?
GTP-binding protein that may be involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity).  Plays a role in the shedding of pathogen spores from intestinal cells (PubMed:24843160).
What are the official names of this protein?
ADP-ribosylation factor-like protein 5.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: ACSA_METPB
Sequence: MSEKVIDVQDAWRERALIDDAKYKEMYAASVSDPETFWAEHGRRIDWSTPFSKVKNTSFAPGNVSIKWFEDGKTNVALNCIDRHLETRGDQTAIIWEGDDPNESQHITYKQLHAEVCRMANVLRNRGVGKGDRVTLYLPMIPEAAYAMLACARLGAIHAIVFGGFSPDSLASRIKGCGSKLVITADEGLRGGRKVPLKANVDEAIKRLDADLVDHVIVVKRTGGNVAMEPGRDVYYHEAAEQVTDECPAEAVEAEHPLFILYTSGSTGQPKGVVHTTGGYLVYASMTHQYVFDYHDGDVYWCTADVGWVTGHSYIVYGPLANGATTLMFEGIPTYPSNSRFWEVIDKHKVNIFYTAPTAIRSLMGGGEGPVKKTSRASLRVLGSVGEPINPEAWDWYYRVVGDSRCSIVDTWWQTETGGILITPLPGATKLKPGSATRPFFGVQPVMVDAEGKELDGACEGNLCIKDSWPGQMRTVYGDHERFEQTYFSTYKNLYFTGDGARRDADGYYWITGRVDDVINVSGHRMGTAEVESSLVAHPKVSEAAVVGYPHNVKGQGIYAYVTLNEGEDGSDELRKELVTWVRKDIGPIASPDLIQFAPGLPKTRSGKIMRRILRKIAEDDFGSLGDTSTLAEPAVVDDLIENRQNRSA
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: B2L13_MOUSE
Sequence: MASSTTASLGFHYETKYVVLSYLGLLSQEKQQGPSPPGVQLDVAPQSLNPEVLLKLKSEIEEELKTLDKEVSEAFTSTGFDCHTSPVFSPANPESSIEDCLAHLGERVSQDLKEPLQKALQTILSQPVTYEAYRECTVETAVHASGWNKLLVPLVLLQHLLLELTRRGQEPLRMLLQFGVMYLEEHAAEFIIQQGGWGSVFSLEPEEEEYPGIIAEDSNDIYILPSDNSGQVSPPESPTVTTSWQSESLPVSLSASQSWHTESLPVSLGPESWQQIAMDPEEVKSLDSSGAGEKSENNSSNSDIVHVEKEEVPEEAFPGAAAPLLTQVPTVEAPEMMRAEKTSPTPSVFVELGEEELEAVTARPEAVERAEGAAQLSEERAGSRKKSHTGEAAAVRGAKSGLPAEGKAVLLFGGAAAVAILAVAVGVALALRRK
What is the function of this protein?
May promote the activation of caspase-3 and apoptosis.
What are the official names of this protein?
Bcl-2-like protein 13, Bcl2-L-13, Bcl-rambo, Protein Mil1.
What is the protein family that this protein belongs to?
Belongs to the Bcl-2 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: HIS2_LISW6
Sequence: MLNDLYEEIKKRKEQPKEGSYTNYLFEKGLDKILKKVGEETTEVIIASKNNNQELVNEVADLTYHLLVLLAEKNVSLSSVQAELERREGKLSTTRDRKEIDEL
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRA_UREU1
Sequence: MVKSIWVAGGCFWGIQKYFDSIKGVRHTIVGYSQGNVINPSYEQVCTQTTNHTETVQVDYDDRFVSLTSILEHLYQIIDPFSLNKQGEDIGNQYRSGIYYVDHEDALIIKNFLLQKQNQTSKKIMIEVHKLHNFNIAEEYHQKYLDKNPNGYCHVNLSLSKKRFN
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: ACT2_ABSGL
Sequence: MSMEEDIAALVIDNASGMCKAGFAGDDAPRAVFPSIVGRPRHQGIMVGMGQKDSYVGDEAQSKRGILTLRYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKSNREKMTQIMFETFNAPAFYVSIQAVLSLYASGRTTGIVLDSGDGVTHTVPIYEGYSLPHAILRLDMAGRDLTDYLMRILAERGHSFTTTAEREIVRDIKEKLCYTGLDFEQEMQTAAQSSALEKSYELPDGQVITVGNERFRAPEALFQPSFLGLESAGIHETTYNSIMKCDVDIRKDLYSNIVMSGGTTMYPGIADRMQKEITALAPSSMKIKIVAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin-2.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RL29_METS3
Sequence: MAILRSKEIWDMEVDEIQDKLVELRAELSKNVSKSAAAGVIENPGKIRELKRTIARVLTILNEKQKEN
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: CCDC_BACSU
Sequence: MMIIVSSIIAVLMAVAVMVVRIKSSDKPVSPKKIILPPIFMSTGALMFLFPVFWVTGAEFLEAFTLGVIFSIFLIKTSKFEIKNNEIYMKRSKAFVFILVGLLVIRIVMKSILSTSIDYGALSGMFWILAFGMIVPWRIAMYLSYRKLHNELQSSNIQMN
What are the official names of this protein?
Protein CcdC.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MNME_LACH4
Sequence: MAQTLTEFDTIAAISTPIGEGGISIVRMSGEDAVKIANEVFKGADLTKVPTHTIHYGHIVDPDTDKTIDESMVTVLRAPKTFTREDIVEINCHGGIVVTNHILQLLLSHGARMADPGEFTKRAFVNGRIDLTQAESVMDIVRAKTDKARQVAVGQLAGGLLHKIQAMRQEILDTLANVEVNIDYPEYDADTVTAKQMADTAKSVIKKIDRLLKTAQEGKILRNGLATAIVGRPNVGKSSLLNYLTQSDKAIVTDVAGTTRDTLEEYVSVKGVPLELIDTAGIHHTDDKVEKIGVERSKKALDRADLVLLLIDASQELTAEDKALIEETKDKKRIIVLNKSDLGQKITVDEMKKQTGSDVILTSILKEKNLDKLEELINKLFFAGIENSNDQVMVTNQRQTSLLTKAKKELQDVVQAVEDGIPIDIAQIDFTGAWDTLGEITGESAPDELVTQLFSQFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLGJ_BUCBP
Sequence: MSTNFFTYLLNNTKINSEKKYNRLIQNKNNQKHSIHKSSNISQQVESLFLYIMFTNMKKSSYKNEFWTTSNSESIYQNMYDQFITQTYDKKGIGLAKIIDNQIQKYKNQKHLTNLEIFDKFSNKLISFKTNNTTDDIDTIIKTSKLFRYL
What are the official names of this protein?
Putative flagellar protein FlgJ homolog.
What is the protein family that this protein belongs to?
Belongs to the FlgJ family.
Protein: RHAR_ECO57
Sequence: MAHQLKLLKDDFFASDQQAVAVADRYPQDVFAEHTHDFCELVIVWRGNGLHVLNDRPYRITRGDLFYIHADDKHSYASVNDLVLQNIIYCPERLKLNLDWQGAIPGFSASAGQPHWRLGSMGMAQARQVIGQLEHESSQHVPFANEMAELLFGQLVMLLNRHRYTSDSLPPTSSETLLDKLITRLAASLKSPFALDKFCDEASCSERVLRQQFRQQTGMTINQYLRQVRVCHAQYLLQHSRLLISDISTECGFEDSNYFSVVFTRETGMTPSQWRHLNSQKD
What is the function of this protein?
Activates expression of the rhaSR operon in response to L-rhamnose.
What are the official names of this protein?
HTH-type transcriptional activator RhaR, L-rhamnose operon transcriptional activator RhaR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_BLOPB
Sequence: MINKIDNIQTDSEIHMKKCIKNFKTNINNIHIGRISPNILNNIRVDYYGISTPLSQVANAIVEDSRTLAITVFDHQLIKSTEKAIFMSDLELIPISYGNTIRVTLPALTEERRHTLIKMVRTEAEKSKIAVRSVRRIANDKTKILLKNKEINEDEEHFFQNEIQKLTNIWIKEIDIILAEKESELMKF
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURB_NITEU
Sequence: MDTPDLQSRTSGIDTRLLRGELRQHEPMKRHVSWRAGGHAACFYQPADLEDLALFLRHWPKDEPVVMIGLGSNLLVRDGGLPGVVITLHAKLNDLSLVEQNESGGLIYAGAGVPCAKLARFAASHNLTGAEFLAGIPGTVGGALAMNAGCYGAETWDRVERVTTIDRSGIVRERTPEDYQVGYRHVELQRTPSSDTPDVWFTGGWFRLRPGKMESSRQAVRTLLTARIKTQPLGFPSAGSVFRNPPGDHAARLIEQCGLKGFRIGDAMVSTLHANFIVNCGHATASEIEAIIDTVQNAVHQATGIRLITEVRIIGQLGGSTQ
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPA_RALPJ
Sequence: MEFSTKALDWAKAGALAAKSDCLVIGLFESQTLAGAAKALDVATKGLVARLVKLGDFEGKRGTSLLLHEVAGVGAARVLLVGLGKEADFTDRAYAEAVRTALRALASTKAASVTWTLTEHTARDKDTAWAVLTAVTLIREASYRFIERHPELKSKRDKNGTGLRKLVLAVPAADAKTASVAAARGTAIANGMDLTRDLGNLPSNICTPTYLANTARQIAKDFKLKVEVLGRKQIEALKMGAFLAVTKGSVEPPAFIVLRYEGGPAKQAPVVLVGKGITFDTGGISLKPGEGMDEMKYDMCGAASVLGTLRAVAEMGLKQNVIAVVPTCENMPSGIATKPGDVVTSMSGQTIEILNTDAEGRLILCDALTYVERFKPAVVIDVATLTGACIIALGHINTGMYARSDALADALVAAGKQSLDTAWRMPLDEEYQEQLKSNFADMGNIGGRPAGSVTAACFLARFTEKYDWAHLDIAGTAWKSGAAKGATGRPVPLLTRFLMDRG
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLGM_SHIFL
Sequence: MSIDRTSPLKPVSTVQPRETTDAPVTNSRAAKTTASTSTSVTLSDAQAKLMQPGSSDINLERVEALKLAIRNGELKMDTGKIADALINEAQQDLQSN
What is the function of this protein?
Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective.  It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA (By similarity).
What are the official names of this protein?
Negative regulator of flagellin synthesis, Anti-sigma-28 factor.
What is the protein family that this protein belongs to?
Belongs to the FlgM family.
Protein: BETI_YERPE
Sequence: MPKVGMQPIRRQQLIEATMAAVNEVGMHEASIAQIAKRAGVSNGIISHYFRDKNGLLEATMRYLIRHLGEAVKQHLAALSVNDPRARLRAIAEGNFDDSQINSAAMKTWLAFWASSMHSPQLYRLQQVNNRRLYSNLCAEFKRCLPREQAQLAAKGMAGLIDGLWLRSALSGEHFNRQEALLIIHNYIEQQLNIKYKC
What is the function of this protein?
Repressor involved in the biosynthesis of the osmoprotectant glycine betaine.  It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator BetI.
Protein: SPRR1_MACMU
Sequence: MSSQQQKQPCTPPPQLQQQQVKQPCQPPPQEPCIPKTKEPCLPKVPEPCHPKVPEPCQPKVPEPCHPKVPEPCPSTVTPAPAQQKTKQK
What is the function of this protein?
Cross-linked envelope protein of keratinocytes.  It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase.  All that results in the formation of an insoluble envelope beneath the plasma membrane.
What are the official names of this protein?
Cornifin, Small proline-rich protein I, SPR-I, Small proline-rich squamous cell marker.
What is the protein family that this protein belongs to?
Belongs to the cornifin (SPRR) family.
What are the subcellular locations of this protein?
Cytoplasm.