PharMolix/UniProtQA huggingface dataset:
Protein: Y037_ROSCS
Sequence: MTDYHIRIRELPATDKPRERLRASGAAALADAELLAILLRVGVEGVNAIQLAQQLLVEFGGWSGLQRAGFEELAQRRGMGEAKTAQLKAALEIGRRLLLASGEERFQIRSPTDAAQLMQIEMSHLDQEQLRAICLDTKNRVQKIQTVYVGSLNASMVRIGEVFKEAIRLNSASIIVVHNHPSGDPTPSPEDIVVTRQMIEAGRLLDIDVLDHLVIGNGRFVSMRERGLAFIKP
What are the official names of this protein?
UPF0758 protein Rcas_0037.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: Z3H7A_HUMAN
Sequence: MSNVSEERRKRQQNIKEGLQFIQSPLSYPGTQEQYAVYLRALVRNLFNEGNDVYREHDWNNSISQYTEALNIADYAKSEEILIPKEIIEKLYINRIACYSNMGFHDKVLEDCNIVLSLNASNCKALYRKSKALSDLGRYKKAYDAVAKCSLAVPQDEHVIKLTQELAQKLGFKIRKAYVRAELSLKSVPGDGATKALNHSVEDIEPDLLTPRQEAVPVVSLPAPSFSHEVGSELASVPVMPLTSILPLQVEESALPSAVLANGGKMPFTMPEAFLDDGDMVLGDELDDLLDSAPETNETVMPSALVRGPLQTASVSPSMPFSASLLGTLPIGARYAPPPSFSEFYPPLTSSLEDFCSSLNSFSMSESKRDLSTSTSREGTPLNNSNSSLLLMNGPGSLFASENFLGISSQPRNDFGNFFGSAVTKPSSSVTPRHPLEGTHELRQACQICFVKSGPKLMDFTYHANIDHKCKKDILIGRIKNVEDKSWKKIRPRPTKTNYEGPYYICKDVAAEEECRYSGHCTFAYCQEEIDVWTLERKGAFSREAFFGGNGKINLTVFKLLQEHLGEFIFLCEKCFDHKPRMISKRNKDNSTACSHPVTKHEFEDNKCLVHILRETTVKYSKIRSFHGQCQLDLCRHEVRYGCLREDECFYAHSLVELKVWIMQNETGISHDAIAQESKRYWQNLEANVPGAQVLGNQIMPGFLNMKIKFVCAQCLRNGQVIEPDKNRKYCSAKARHSWTKDRRAMRVMSIERKKWMNIRPLPTKKQMPLQFDLCNHIASGKKCQYVGNCSFAHSPEEREVWTYMKENGIQDMEQFYELWLKSQKNEKSEDIASQSNKENGKQIHMPTDYAEVTVDFHCWMCGKNCNSEKQWQGHISSEKHKEKVFHTEDDQYCWQHRFPTGYFSICDRYMNGTCPEGNSCKFAHGNAELHEWEERRDALKMKLNKARKDHLIGPNDNDFGKYSFLFKDLN
What is the function of this protein?
May be a specific regulator of miRNA biogenesis.  Binds to microRNAs MIR7-1, MIR16-2 and MIR29A hairpins recognizing the 3'-ATA(A/T)-5' motif in the apical loop.
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 7A.
Protein: CCME_NEOSM
Sequence: MLLLRWKRFWFLSLGILLFSGVVSLMLFNLSESISFFYLPSDVARVVASNREIKVGGIIKAIKKSKDGVRFLLSDGAAEIEVLYEGILPSLVQDGINVVVVARFEGGLLLAKRVLVKHDERYYPPEDFIKSVRGE
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: PDXS_NOCFA
Sequence: MTQEFAVTTPETTQTVGTARVKRGMAEMLKGGVIMDVVTPEQAKIAEDAGAVAVMALERVPADIRAQGGVSRMSDPDMIDGIINAVSIPVMAKARIGHFVEAQILQSLGVDYIDESEVLTPADYTNHIDKWQFTVPFVCGATNLGEALRRITEGAAMIRSKGEAGTGDVSNATTHMRKIRQEIRKLAALPEDELYVAAKELQAPYELVREVAETGKLPVVLFTAGGIATPADAAMMMQLGAEGVFVGSGIFKSGNPAQRAEAIVKATTFYDDPDVLAKVSRGLGEAMVGINVEEIPQPHRLAERGW
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: NUOC_XYLFM
Sequence: MAEQTLSFVDCLTSRFPTVRVSVAQPRGEITLDVPVVEWCAVCKGLRDEFDFEQLSDLCGVDYLGYGNAEWDTTGVSAQGFSRGVAGKAVGRFAWGEFPSAGTNDGTQPWDVPQERFAVLAHLISYRHNRRLRVRCFASNDALPIVASLTDVWPGVNWFEREAFDLFGIVFEGHLDLRRILTDYGFIGHPFRKDFPLTGNVEVRYDEEKKRVVYVPVTSVEPRVSVPRVIRDDARFGAAAGESTHSETV
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MCTS1_RAT
Sequence: MGKGRFDEKENVSNCIQLKTSVIKGIKNQLLEQFPGIEPWLNQIMPKKDPVKIVRCHEHIEILTVNGELLFFRQREGPFYPTLRLLHKYPFILPHQQVDKGAIKFVLSGANIMCPGLTSPGAKLYPAAVDTIVAIMAEGKQHALCVGVMKMSAEDIEKVNKGIGIENIHYLNDGLWHMKTYK
What is the function of this protein?
Anti-oncogene that plays a role in cell cycle regulation; decreases cell doubling time and anchorage-dependent growth; shortens the duration of G1 transit time and G1/S transition.  When constitutively expressed, increases CDK4 and CDK6 kinases activity and CCND1/cyclin D1 protein level, as well as G1 cyclin/CDK complex formation.  Plays a role as translation enhancer; Recruits the density-regulated protein/DENR and binds to the cap complex of the 5'-terminus of mRNAs, subsequently altering the mRNA translation profile; Up-regulates protein levels of BCL2L2, TFDP1, MRE11, CCND1 and E2F1, while mRNA levels remains constant.  Hyperactivates DNA damage signaling pathway; increased gamma-irradiation-induced phosphorylation of histone H2AX, and induces damage foci formation.  Increases the overall number of chromosomal abnormalities such as larger chromosomes formation and multiple chromosomal fusions when overexpressed in gamma-irradiated cells.  May play a role in promoting lymphoid tumor development: lymphoid cell lines overexpressing MCTS1 exhibit increased growth rates and display increased protection against apoptosis.  May contribute to the pathogenesis and progression of breast cancer via promotion of angiogenesis through the decline of inhibitory THBS1/thrombospondin-1, and inhibition of apoptosis.  Involved in the process of proteasome degradation to down-regulate Tumor suppressor p53/TP53 in breast cancer cell; Positively regulates phosphorylation of MAPK1 and MAPK3 (By similarity).
What are the official names of this protein?
Malignant T-cell-amplified sequence 1, MCT-1.
What is the protein family that this protein belongs to?
Belongs to the MCTS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_CALBD
Sequence: MKLYELKPAPGSKKNRKRVGRGESSGHGKTSTRGHKGQWARSGGGVRPGFEGGQMPLTRRIPKRGFKNINKKVYTEVNVEKLERFDNDTVITPELLLKERVISKIEKDGVKILGRGELTKRLIVRVQKVSEGARKKIEASGGKVEVI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: BT2A2_MOUSE
Sequence: MEPTTSLRSCPIASLLFFLVLSLFVLVSAQFTVIGPAEPILAMVGENTTLHCHLSPERNAEEMEVRWFRWRFFPAVLVYRGHQERPEEQMVAYRGRTTFMRTDISKGRVALIIHNVTAYDNGIYCCYFQEGRSYDQATMKLMVASLGSEPLIKMKTLEDGSILLECTSEGWYPEPRAVWRDPYDEVVPALEEEYTADREGLFTVTMTIIIRDCSVRNMTCSVNNTLLSQEVESVILIPESFVPSLPLWMVAVAVTLPVVMLILLTSGSICLVKKHRRKKSILSAEKEAEYEEKEAARQLQEELRWRRTLLHAADVVLDPDTAHPELFLSDDQRSVIRGSSRQSVPDNPERFDCRPCVLGRESFSSGKHYWEVEVENVMVWAIGVCRDSVERKGEALLVPQNGFWTLEMFGSQYRALSSPEKIIPLKERLHRIAVFLDCEGGDISFYNMRDRSHIYTCPPVTFTGPLRPFFRLGSDDSPLFICPAFTGAQGVTIPEGGLFLYKTRPISQSLVRKP
What is the function of this protein?
Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.
What are the official names of this protein?
Butyrophilin subfamily 2 member A2.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. BTN/MOG family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: TBA2_HORVU
Sequence: MRECISIHIGQAGIQVGNACWELYCLEHGIQPDGQMPGDKTVGGGDDAFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGAYRQLFHPEQLISGKEDAANNFARGHYTIGKEIVDLCLDRIRKLSDNCTGLQGFLVFNAVGGGTGSGLGSLLLERLSVDYGKKSKLGFTVYPSPQVSTSVVEPYNSVLSTHSLLEHTDVSILLDNEAIYDICRRSLDIERPTYTNLNRLVSQVISSLTASLRFDGALNVDVNEFQTNLVPYPRIHFMLSSYAPVISAEKAYHEQLSVAEITNSAFEPSSMMAKCDPRHGKYMACCLMYRGDVVPKDVNAAVATIKTKRTIQFVDWCPTGFKCGINYQPPGVVPGGDLAKVQRAVCMISNSTSVVEVFSRIDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGAEFDDGEDGDEGDEY
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin alpha-2 chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: TSN5_RAT
Sequence: MSGKHYKGPEVSCCIKYFIFGFNVIFWFLGITFLGIGLWAWNEKGVLSNISSITDLGGFDPVWLFLVVGGVMFILGFAGCIGALRENTFLLKFFSVFLGIIFFLELTAGVLAFVFKDWIKDQLYFFINNNIRAYRDDIDLQNLIDFTQEYWQCCGAFGADDWNLNIYFNCTDSNASRERCGVPFSCCTKDPAEDVINTQCGYDARQKPEVDQQIVIYTKGCVPQFEKWLQDNLTIVAGIFIGIALLQIFGICLAQNLVSDIEAVRASW
What is the function of this protein?
Regulates ADAM10 maturation and trafficking to the cell surface.  Promotes ADAM10-mediated cleavage of CD44.
What are the official names of this protein?
Tetraspanin-5, Tspan-5, Transmembrane 4 superfamily member 9.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TVA20_HUMAN
Sequence: MEKMLECAFIVLWLQLGWLSGEDQVTQSPEALRLQEGESSSLNCSYTVSGLRGLFWYRQDPGKGPEFLFTLYSAGEEKEKERLKATLTKKESFLHITAPKPEDSATYLCAVQ
What is the function of this protein?
V region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition (PubMed:24600447).  Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.  Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333).  Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.  In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.  The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462).  The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement.  This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells.  Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585).
What are the official names of this protein?
T cell receptor alpha variable 20.
What are the subcellular locations of this protein?
Cell membrane.
Protein: NORR_ECOSE
Sequence: MSFSVDVLANIAIELQRGIGHQDRFQRLITTLRQVLECDASALLRYDSRQFIPLAIDGLAKDVLGRRFALEGHPRLEAIARAGDVVRFPADSELPDPYDGLIPGQESLKVHACVGLPLFAGQNLIGALTLDGMQPDQFDVFSDEELRLIAALAAGALSNALLIEQLESQNMLPGDAAPFEAVKQTQMIGLSPGMTQLKKEIEIVAASDLNVLISGETGTGKELVAKAIHEASPRAVNPLIYLNCAALPESVAESELFGHVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRSLRVDVRVLAATNRDLREEVLAGRFRADLFHRLSVFPLSVPPLRERGDDVILLAGYFCEQCRLRLGLSRVVLSAGARNLLQHYSFPGNVRELEHAIHRAVVLSRATRSGDEVILEAQHFAFPEVTLPPPEAAAVPVVKQNLREATEAFQRETIRQALAQNHHNWAACARMLETDVANLHRLAKRLGLKD
What is the function of this protein?
Required for the expression of anaerobic nitric oxide (NO) reductase, acts as a transcriptional activator for at least the norVW operon.  Activation also requires sigma-54.
What are the official names of this protein?
Anaerobic nitric oxide reductase transcription regulator NorR.
Protein: NPVF_MOUSE
Sequence: MEIISLKRFILLTVATSSFLTSNTFCTDEFMMPHFHSKEGDGKYSQLRGIPKGEKERSVSFQELKDWGAKNVIKMSPAPANKVPHSAANLPLRFGRTIDEKRSPAARVNMEAGTRSHFPSLPQRFGRTTARSPKTPADLPQKPLHSLGSSELLYVMICQHQEIQSPGGKRTRRGAFVETDDAERKPEK
What is the function of this protein?
Neuropeptide RFRP-1 acts as a potent negative regulator of gonadotropin synthesis and secretion.  Neuropeptides NPSF and NPVF efficiently inhibit forskolin-induced production of cAMP.  Neuropeptide NPVF blocks morphine-induced analgesia (By similarity).
What are the official names of this protein?
Pro-FMRFamide-related neuropeptide VF, FMRFamide-related peptides.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: FLIW_CLOD6
Sequence: MMKITLKKGILGFENLKEYELLDIENEDILKEFNSTEEDCIGFIVVSPFEIIKEYEIVLNQETIEKLEVKSPNDIMLLNIITVGQTLEESTVNMKAPIVINVRNNCGMQIILQDEEYSIWHPLLRGDGGC
What is the function of this protein?
Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin.  Binds to flagellin and participates in the assembly of the flagellum.
What are the official names of this protein?
Flagellar assembly factor FliW.
What is the protein family that this protein belongs to?
Belongs to the FliW family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAD14_ORYSJ
Sequence: MGRGKVQLKRIENKINRQVTFSKRRSGLLKKANEISVLCDAEVALIIFSTKGKLYEYATDSCMDKILERYERYSYAEKVLISAESDTQGNWCHEYRKLKAKVETIQKCQKHLMGEDLESLNLKELQQLEQQLENSLKHIRSRKSQLMLESINELQRKEKSLQEENKVLQKELVEKQKVQKQQVQWDQTQPQTSSSSSSFMMREALPTTNISNYPAAAGERIEDVAAGQPQHVRIGLPPWMLSHING
What is the function of this protein?
Probable transcription factor.  May be involved in the control of flowering time.
What are the official names of this protein?
MADS-box transcription factor 14, FDRMADS6, OsMADS14, Protein AGAMOUS-like 10, Protein APETALA1-like B, RMADS211.
What are the subcellular locations of this protein?
Nucleus.
Protein: NDK_PSEAE
Sequence: MALQRTLSIIKPDAVSKNVIGEILTRFEKAGLRVVAAKMVQLSEREAGGFYAEHKERPFFKDLVSFMTSGPVVVQVLEGEDAIAKNRELMGATDPKKADAGTIRADFAVSIDENAVHGSDSEASAAREIAYFFAATEVCERIR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.  The 12-kDa membrane-associated form synthesizes GTP in preference to other nucleoside triphosphates.  Important for alginate synthesis.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Ndk is predominantly cytoplasmic. The 12-kDa form is predominantly membrane-associated.
Protein: WEE2_XENTR
Sequence: MRTAMSCGGGLAQRLDFSSSDEEDGMSPGLEEGSHSNQRGSPVNSWRANNCPFPITPQRNERGLSPSQEELSPCSDYSPVPSDKGVGGECPGTPLHYSTWKKLKLCDTPYTPKSLLYKTLPSPGSRVQCRGQRLLRFVAGTGAELDDPALVNVNPFTPESYRQANFHPNGKRKERPEDDCSAEPQMKYAEKEHPAVFQSKRFVLRETNMVSRYKTEFLEIEKIGAGEFGSVFKCVKRLDGCFYAIKRSKKPLAGSTDEQLALREVYAHAVLGHHPHVVRYYSAWAEDDHMIIQNEYCNGGSLQDLIMENKKEGRFVPEQELKEILLQVSMGLKYIHSSGLVHMDIKPSNIFICRKQTEVGQDESDGEDDLSSASVLYKIGDLGHVTSILNPQVEEGDSRFLANEILQEDYRQLPKADIFALGLTITLAAGAGPLPCNEDSWHHIRKGNLPHIPQPLTPAFLALLKLLVHPDPVMRPPAVSLAKNSLLRRCVGKAAQLQKQLNVEKFKTAMLERELKAAKLAHGSGKDECSDLPPMSDFSCRGRKRLVGAKNARSLSFTCGGY
What is the function of this protein?
Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits cdk1 and acts as a regulator of meiosis.  Required to maintain meiotic arrest in oocytes by phosphorylating cdk1 at 'Tyr-15', leading to inhibit cdk1 activity and prevent meiotic reentry (By similarity).
What are the official names of this protein?
Wee1-like protein kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: VATE_PYRHO
Sequence: MNGAELIIQEINKEAERKIEYILNEARQQAEKIKEEARRNAEAKAEWIIRRAKTQAELEKQRIIANARLEVRRKRLAIQEEIISSVLEEVKRRLETMSEDEYFESVKALLKEAIKELNEKKVRVMSNEKTLGLIASRIEEIKSELGDVSIELGETVDTMGGVIVETEDGRIRIDNTFEARMERFEGEIRSTIAKVLFG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: GP3_PRRSL
Sequence: MAHQCARFHFFLCGFICYLVHSALASNSSSTLCFWFPLAHGNTSFELTINYTICMPCSTSQAARQRLEPGRNMWCKIGHDRCEERDHDELLMSIPSGYDNLKLEGYYAWLAFLSFSYAAQFHPELFGIGNVSRVFVDKRHQFICAEHDGHNSTVSTGHNISALYAAYYHHQIDGGNWFHLEWLRPLFSSWLVLNISWFLRRSPVSPVSRRIYQILRPTRPRLPVSWSFRTSIVSDLTGSQQRKRKFPSESRPNVVKPSVLPSTSR
What is the function of this protein?
Minor envelope protein.
What are the official names of this protein?
Glycoprotein 3, Protein GP3.
What is the protein family that this protein belongs to?
Belongs to the arteriviridae GP3 protein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host endoplasmic reticulum membrane; Single- pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein. Secreted. Note=Only a small fraction of GP3 synthesized in infected cells ends up in virions. The transmembrane region probably functions as an uncleaved signal (By similarity).
Protein: RS19_PYRNV
Sequence: MSSKEQEAQKGKQGWITPAVIPPEEWGTFRYRGKTLEELLNLPMDEFIKLLPARQRRSLKRGLKPEHRKLLEKIRKAKRLAAQGKKVTIKTHSRDMIILPEMVGLTIHVYNGITYIPVFISPWHIGHYLGEFALTTKVVQHGEPGLKATRSSLHIAAK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: HIR3C_HIRME
Sequence: VVYTDCTESGQNLCLCQGSNVCGQGNKCILGSNGEKNQCVTGEGTPKPQSHNDGDFEEIPEEYLQ
What is the function of this protein?
Hirudin is a potent thrombin-specific protease inhibitor.  It forms a stable non-covalent complex with alpha-thrombin, thereby abolishing its ability to cleave fibrinogen.
What are the official names of this protein?
Hirudin-3B', Hirudin IIIB'.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I14 (hirudin) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RECR_STRA1
Sequence: MLYPTPIAKLIDSFSKLPGIGTKTATRLAFYTIGMSDEDVNEFAKNLLAAKRELTYCSVCGNLTDDDPCLICTDKTRDQSVILVVEDSKDVSAMEKIQEYNGLYHVLHGLISPMNGISPDDINLKSLITRLMDGQVTEVIVATNATADGEATSMYISRVLKPAGIKVTRLARGLAVGSDIEYADEVTLLRAIENRTEL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: GATA_WOLSU
Sequence: MITLKQAMELAPQALSEIKTEIRKKVSESSLNAYVGEIRDSLEGGIPILVKDNINVKGSELTCGSKILEGYVAPYNATVIEKLHAQGMSAFGRSNMDEFAMGSTTESSAHGKTLNPVDSSRVPGGSSGGSASAVAGGLAIAALGSDTGGSIRQPAAFCGCVGLKPTYGRVSRYGLVAYASSLDQIGPITQNVEDAAILFDAISGHDGRDSTSASLAPTQTHKALDANKKQTIAILPDLLKEASKPIQEAYFETVKILESEGHKIVEKSMLNTAYHISAYYVLCTAEASSNLARFDGVRYGRRAEAQNLKELYIKSRTEGFGEEVKRRILLGSFVLSSGYYDAYYLKAQKVRHLIKNQYDEIFKDCDLVLSPVAPTVAPKFGSTSTPLEMYLGDIYTISINLAGLPALSLPVGKSEEGLPVGMQLIGKAFGEQSVLDGALSLERAIGFAL
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: RUTE_KLEP3
Sequence: MNDAINHTACETLFTQARTHNGWLDKPVSDAQLQAIWDLMKMGPTSANCSPARIVFVRSAEGKEKLGPTLSSGNLQKTMQAPVTAIVAWDRAFYDRLPTLFPHGDARSWFTSSPQLAEETAFRNSSLQAAYLIFACRALGLDTGPMSGFDREKVDAAFFADNGWKSNLLVNIGYGDPGKLYGRLPRLSFDEACLLA
What is the function of this protein?
May reduce toxic product malonic semialdehyde to 3-hydroxypropionic acid, which is excreted.
What are the official names of this protein?
Probable malonic semialdehyde reductase RutE.
What is the protein family that this protein belongs to?
Belongs to the nitroreductase family. HadB/RutE subfamily.
Protein: GMSS_ECO57
Sequence: MKKATLVIGVIGADCHAVGNKVLDRVFSNHDFRVINLGVMVSQDEYIDAAIETGADAIVVSSIYGHGDIDCLGMRERCIERGLGDILLYVGGNLVVGKHDFADVETKFKEMGFDRVFAPSHDLEDVCQLMAHDINQRHDVDTRILEEAI
What is the function of this protein?
Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
What are the official names of this protein?
Glutamate mutase sigma subunit, Glutamate mutase S chain, Glutamate mutase small subunit, Methylaspartate mutase.
What is the protein family that this protein belongs to?
Belongs to the methylaspartate mutase GlmS subunit family.
Protein: ZIC2B_XENLA
Sequence: MLLDAGPQFPALGVGTFARHHHHHHHHHAAVAAAAAAAAEMQERELSLAQNSFVEPTHMGAFKMNPGGGSGGGSGGGGGAGPNGGAGASGPHDLSPPGQTSAFTSQAGYPASALAPHSAYTGAAAFNSPRDFLFRGRGFAEGSAAAGGGQHGLFGPPAGSLHHHPHHHHQLSHGEHPQGHLLFPGIHDQHAAASQNTLGGQMRLGLPGEVFGRTDQYRQVSSPRGDPYTAAQLHNQYSPMNMGMNMAAHHHHHHHHPGAFFRYMRQQCIKQELICKWIDPEQLNNPKKSCNKTFSTMHELVTHMSVEHVGGPEQSNHICFWEECAREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFQCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKMCDKSYTHPSSLRKHMKVHESSPQGSESSPAASSGYESSTPPGLVSPNSETQNPNLSPAAVSAVHSVSSGASGTLASNFNEWYV
What is the function of this protein?
Transcriptional repressor that inhibits neurogenesis and induces neural and neural crest differentiation.  Regulates anteroposterior patterning in early development by inhibiting expression of the nodal genes through the inhibition of vegt.  Required for gastrulation movements and for proper anterior neural and axial development.  May also act as a transcriptional activator.  May bind to the minimal GLI-consensus sequence 5'-TGGGTGGTC-3' (By similarity).
What are the official names of this protein?
Zinc finger protein ZIC 2-B, Zic-related-2, ZIC-R2, Zinc finger protein of the cerebellum 2-B.
What is the protein family that this protein belongs to?
Belongs to the GLI C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: OBGM_ARATH
Sequence: MWLIRAIVPVRYLGSYKRPQKPPWMRNPVVFYSDFSEKKGKVAPLQETRMRDRFTLYARGGEGGSGCSSVRRSRADRYGKPDGGNGGRGGDVILECTHAVWDFSGLQPHIKGGKAGHGTSKNRIGNRGEDKVLLVPIGTVIHLQEGEIPSQVENESPKDLDPWDLPGSLVEDPASEENSDVHQETMSESDQDDTEQESLTRQLGMPKEADFEDDDEEIDQIRYNVAELTQQGQRVIIARGGEGGLGNVSATRYVRGSKFAKSTIRQTNLRSMEDDAEEDDERSSIKAGLLGSEAVLILELKSIADVGLVGMPNAGKSTLLGALSRAKPRVGHYAFTTLRPNLGNVNYDDFSMTVADIPGLIKGAHQNRGLGHNFLRHIERTKVLAYVVDLASGLDGCEGLTPWQQLRDLVMELEFHEEGLSDRSSLIVANKIDEEGAEERLKELKRRVKGVKIFPVCAVLEEGVAELKDGLKMLVDGNGEPSERLKLENICVD
What is the function of this protein?
May bind GTP and have GTPase activity.
What are the official names of this protein?
Probable GTP-binding protein OBGM, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Mitochondrion.