PharMolix/UniProtQA huggingface dataset:
Protein: GGLO_PIG
Sequence: MVHGHKGVKFQNWAKTYGCCPEMYYQPTSVEEIREVLALARQQNKRVKVVGGGHSPSDIACTDGFMIHMGKMNRVLKVDMEKKQVTVEAGILLADLHPQLDKHGLALSNLGAVSDVTAGGVIGSGTHNTGIKHGILATQVVELTLLTPDGTVLVCSESSNAEVFQAARVHLGCLGVILTVTLQCVPQFHLQETTFPSTLKEVLDNLDSHLKKSEYFRFLWFPHSENVSVIYQDHTNKPPSSSANWFWDYAIGFYLLEFLLWISTFVPGLVGWINRFFFWLLFNGKKENCNLSHKIFTYECRFKQHVQDWAIPREKTKEALLELKAMLEAHPKVVAHYPVEVRFTRADDILLSPCFQRDSCYMNIIMYRPYGKDVPRLDYWLAYETIMKKVGGRPHWAKAHNCTRKDFEKMYPAFRKFCAIREKLDPTGMFLNAYLEKVFY
What is the function of this protein?
Oxidizes L-gulono-1,4-lactone to hydrogen peroxide and L-xylo-hexulonolactone which spontaneously isomerizes to L-ascorbate.
What are the official names of this protein?
L-gulonolactone oxidase, LGO, L-gulono-gamma-lactone oxidase, GLO.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
What are the subcellular locations of this protein?
Microsome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: IBR5_ARATH
Sequence: MRKRERENPCSICGHYHKYEEGEVCGVCGHCMPVSSDTVAPQQVHVSAFPSEILPEFLYLGSYDNASRSELLKTQGISRVLNTVPMCQNLYRNSFTYHGLDNEKVLQFDDAIKFLDQCEKDKARVLVHCMSGKSRSPAVVVAYLMKRKGWRLAESHQWVKQRRPSTDISPEFYQQLQEFEQGIFGSEMMSAMNINDAPTFGFGFPKIDNQAQAPVFNNAPTSSIFSSPASSIPPQEFTFGATPPKPTTGGDIAMDGS
What is the function of this protein?
Required for the transduction of auxin and abscisic acid (ABA) signaling pathways.  Dephosphorylates and inactivates the MAP kinase MPK12.
What are the official names of this protein?
Protein-tyrosine-phosphatase IBR5, Protein INDOLE-3-BUTYRIC ACID RESPONSE 5, Protein IBA RESPONSE 5, SKP1-interacting partner 33.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GALA_PELRI
Sequence: GWTLNSAGYLLGPHAIDNHRSFNDKHGLA
What is the function of this protein?
Contracts smooth muscle of the gastrointestinal and genitourinary tract, regulates growth hormone release, modulates insulin release, and may be involved in the control of adrenal secretion.
What are the official names of this protein?
Galanin.
What is the protein family that this protein belongs to?
Belongs to the galanin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TXUA_UROYA
Sequence: MKATALLIAVFILFSVFGDMGYCEFCDTPHCTRVCYDHCVRLNKHYKTCCMTNINDRIRMECLCEDKTGIKPYYPNNI
What are the official names of this protein?
Toxin-like protein 10.
What are the subcellular locations of this protein?
Secreted.
Protein: KCY_ECOHS
Sequence: MTAIAPVITIDGPSGAGKGTLCKAMAEALQWHLLDSGAIYRVLALAALHHHVDVASEDALVPLASHLDVRFVSTNGNLEVILEGEDVSGEIRTQEVANAASQVAAFPRVREALLRRQRAFRELPGLIADGRDMGTVVFPDAPVKIFLDASSEERAHRRMLQLQEKGFSVNFERLLAEIKERDDRDRNRAVAPLVPAADALVLDSTTLSIEQVIEKALQYARQKLALA
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1430_STRTD
Sequence: MYSIVAEESGLLPRERLLQKGAEVLSDQELLAIVLRTGTRSESVLSMANRILKGMTSLADLSRLSLNELQKIPGIGRVKSIELKAMVELAKRIEKAELARSEQIMSSQQVARRMMLDIGDKPQEHLVAIYLDTQNRIIQQKTVFIGGVRRSIAEPREILHYACHLMATSLIVVHNHPSGEAYPSRNDIDFTQKIKRSCDDLGICLLDHLIVGKSTYYSFREEREDFEL
What are the official names of this protein?
UPF0758 protein STER_1430.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: LGT_CITK8
Sequence: MTSSYLHFPEFDPVIFSIGPVALHWYGMMYLVGFVFAMWLAIRRANRPGSGWTKNEVENLLYAGFLGVFLGGRIGYVLFYNFPLFLENPLYLFRVWDGGMSFHGGLIGVILVMVIFARRTKRSFFQVSDFIAPLIPFGLGAGRLGNFINGELWGRVDPSFPFAMLFPGSRAEDIELLPSNPQWQSIFDTYGVLPRHPSQLYELVLEGIVLFIILNLFIRKSRPMGAVSGLFLIGYGAFRIIVEFFRQPDAQFTGAWVQYISMGQILSIPMIVAGVIMMVWAYRRSPQQHVS
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLMS_MYCS2
Sequence: MCGIVGYVGHRPARDIVVDALRRMEYRGYDSAGIALIDGNGGLTVRRRAGRLANLEATLAETDSNDGDGLGGSTGLGHTRWATHGRPTDRNAHPHRDAAGKIAVVHNGIIENFAPLRAELEAAGVEFASDTDTEVAVHLVARQYTQGDTAGDFPASVLAVLQRLEGHFTLVFASADDPGTIVAARRSTPLVLGIGDGEMFVGSDVAAFIEHTRDAVELGQDQAVVLTADGYRITDFAGNDHLEAGRDFREFHIDWDLNAAEKGGYDYFMLKEIAEQPSAVADTLLGHFDKNRIVLDEQRLSDQELREIDKVFIVACGTAYHSGLLAKYAIEHWTRLPVEVELASEFRYRDPVLDRSTLVIAISQSGETADTLEAVRHAKTQKAKVLAICNTNGSQIPREADAVLYTRAGPEIGVAATKTFLAQIAANYLVGLALAQARGTKYPDEVAREYRELEAMPDLIKRVLAGMDSVAALAERFAPSSTVLFLGRHVGYPVALEGALKLKELAYMHAEGFAAGELKHGPIALIDENLPVIVVMPSPKNAAMLHAKLLSNIREIQARGAVTVVIAEEDDDTVRPYADHLIEIPSVSTLFQPLLSTIPLQVFAAGVARARGYDVDKPRNLAKSVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG5_NEOFI
Sequence: MRTSSRMENQASLSSIQRAVWDGKLPLQITLASSESRTYDQTDPYLIACPRISYLPSLLPRLRAFFSSSLIEPNSQPHEGWFSFEGVPLKWHLPVGLLYDLYAGADPASKGTRIDETDHPSSSLSDTLPWRLTVHFSDWPDEELVRLDADGMVMHDAFINSVKEADFLRNGTAKGIMTLSKEDSAGLWQAVQDVDLPSFQRISNILLPPPNQPFRNIPIRFFLPLSPDSGSPSLKVVQSPLPPSIPVATNTSQSTNLRNSPATQVQTLGSALHSLLPNLFPSRRTPVLAKPVLHGAAVPMSAPIEELVRSCAYGDGWAYIVIRMMG
What is the function of this protein?
Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.  Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation.  Required for selective autophagic degradation of the nucleus (nucleophagy).  Also required for mitophagy, which eliminates defective or superfluous mitochondria in order to fulfill cellular energy requirements and prevent excess ROS production.  Conjugation with atg12, through a ubiquitin-like conjugating system involving atg7 as an E1-like activating enzyme and atg10 as an E2-like conjugating enzyme, is essential for its function.  The atg12-atg5 conjugate acts as an E3-like enzyme which is required for lipidation of atg8 and atg8 association to the vesicle membranes (By similarity).
What are the official names of this protein?
Autophagy protein 5.
What is the protein family that this protein belongs to?
Belongs to the ATG5 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: RHO5_SCHPO
Sequence: MTTELRRKLVIVGDGACGKTCLLIVFSKGTFPEVYVPTVFENYVADVEVDGRHIELALWDTAGQEDYDRLRPLSYPDSHVVLICFSVDAPESLDNVQEKWISEVLHFCSNLPILLVGCKVDLRNDPKTIEELSKTSQKPITFEEGQVVAQKIGAYKYLECSAKLNEGVNEVFETAARASMLKFKPASVPKTKKKKHCILL
What are the official names of this protein?
GTP-binding protein rho5.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: Y2500_BACMK
Sequence: MNKLTTKLVVAIGIGAALYGVLGLWGFSIAPNTFIKPALAILTVFGALFGPVAGLLIGLIGHTVTDTIAGWGIWWGWVISSGIIGLAMGLIQKRVGFSVKHGTYNNRDISYFTIAGLIGIVIAIIFAGSFDIIVMGEPFDKIVIQVLGATIADVIVFLVLGLPITIGLAKSNRKHTHLKIEK
What are the official names of this protein?
UPF0397 protein BcerKBAB4_2500.
What is the protein family that this protein belongs to?
Belongs to the UPF0397 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HIS3_ACISJ
Sequence: MDTMNWLDQVKWDAQGLVPVIAQEAATGDVLMFAWMNREALAKTAELGRAVYYSRSRGKLWFKGEESGHVQQVHDIRLDCDSDVVLLKVTQLGHEPGIACHTGRHSCFFNALQNGAWQAVDPVLKDPESIYK
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAK_BORA1
Sequence: MSKIIGIDLGTTNSCVAVMDGGQVKIIENAEGARTTPSIVAYMEDGEILVGAPAKRQAVTNPKNTLYAVKRLIGRKFDEKAVQKDIHLMPYTITKADNGDAWVEVRGSKLAPPQVSAEVLRKMKKTAEDYLGEPVTEAVITVPAYFNDSQRQATKDAGRIAGLEVKRIINEPTAAALAFGLDKTEKGDRKIAVYDLGGGTFDVSIIEIADVDGEKQFEVLSTNGDTFLGGEDFDQRIIDYIIGEFKKEQGVDLSKDVLALQRLKEAAEKAKIELSSSQQTEINLPYITADASGPKHLNLKITRAKLESLVEELIERTIEPCRVAIKDAGVKVSDIDDVILVGGMTRMPKVQEKVKEFFGREPRKDVNPDEAVAAGAAIQGSVLSGDRKDVLLLDVTPLSLGIETLGGVMTKMIQKNTTIPTRFSQTFSTADDNQPAVTIKVFQGEREIAAGNKALGEFNLEGIPPAPRGLPQIEVTFDIDANGILHVSAKDKGTGKENKITIKANSGLSEDEIQRMVKDAEANAEEDHRLAELALARNQADALVHATRKSLTEYGDKLEAAEKESIEKALKDVEESLKAGDKAEIDAKVEALTQASQKLGEKMYADAQAQQAAQQASHQQAADNAKPVDDNVVDADFKEVKRDN
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: PDXT_BACCZ
Sequence: MVKIGVLGLQGAVREHVKSVEASGAEAVVVKRIEQLEEIDGLILPGGESTTMRRLIDKYDFMEPLRTFAKSGKPMFGTCAGMILLAKTLIGYDEAHIGAMDITVERNAFGRQKDSFEAALSIKGVGEDFVGVFIRAPYVVNVADDVEVLSTHGDRMVAVRQGPFLAASFHPELTDDHRVTAYFVEMVKEAKMKKVV
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: EG04A_MDBVW
Sequence: MMSEKFALVLLVACIAFIGIETSPINSDSWKDGFCGENEAYDSMRRGCEKRCDDHNPTFCFKFTTVCWCEKGYVRDKSDTCIKVEDCPNVSENLEFSETIIGM
What are the official names of this protein?
Probable protease inhibitor Egf0.4a.
What is the protein family that this protein belongs to?
Belongs to the polydnaviridae EGF-like motif protein family.
Protein: HBB_CHEKU
Sequence: VEWTDFERATIQDIFSKMDYETVGPATLTRTVIVYPWTLRYFAKFGNICSTAAILGNKEIAKHGTTILHGLDRGVKNMDDIKNTYAELSKLHSEKLHVDPDNFRLLSDCLTIVVAAKMGKDFTGEVQAAFQKFLSVVVNSLGRQYH
What is the function of this protein?
Involved in oxygen transport from gills to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: PLC2_CAEEL
Sequence: MENFWSIVVFFLLSILFILYNISTVCHYYMRISFYYFTILLHGMEVCVTMIPSWLNGKGADYVFHSFFYWCKWTGVHTTVYGYEKTQVEGPAVVICNHQSSLDILSMASIWPKNCVVMMKRILAYVPFFNLGAYFSNTIFIDRYNRERAMASVDYCASEMKNRNLKLWVFPEGTRNREGGFIPFKKGAFNIAVRAQIPIIPVVFSDYRDFYSKPGRYFKNDGEVVIRVLDAIPTKGLTLDDVSELSDMCRDVMLAAYKEVTLEAQQRNATRRGETKDGKKSE
What is the function of this protein?
Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
What are the official names of this protein?
Putative 1-acyl-sn-glycerol-3-phosphate acyltransferase acl-2, 1-AGP acyltransferase, 1-AGPAT, Lysophosphatidic acid acyltransferase, LPAAT.
What is the protein family that this protein belongs to?
Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GB_GPCMV
Sequence: MRPVRGIARSRILSCSWRGTWTSALTILYLGVYCESTTVTPTTVEDTTVSNGNHSDASRNNTVIRNLTASVDFSQRKLYPYRICSMSMGTDLVRFARTIQCVPFNPRVNSEEGIMLIYKRNILPYVFTAYTYQKELLFQRSYKYVTYDYLLGYSREFVALPMWEIFLVNSRGQCYTSHQRVIGADRYIAYHNDNEVNETMWLMRDDMGNDDTYRYITVKEHARTPGSVWLYKETCSMNCIVTKTKGKSKFPYDMFVLPSGVIVNISPFYNGSNGKTFREQREKFHIWSNYSILKDFGSRALEARIVPKMAFYEREDVVIGWEVNDQSNVTCEMILWETVDRAIRTEYENAFHYVARTLTSTFVENKYSPDNNLTEDDIKCFKNDAQKKIEEVFLRDYNETYDMDGNATYHVTTGGLVIVWQGLKQKSLKALEIAANESAVSATGSNSRRKRSLPDESTGDISYAQLQFAYDTLRTYINQALGHIAEAWCLDQKRTAEVLHELSKINPSNILSAIFGVPVAARVVGDVISLAKCIEVNQSTVLIKGDMRKFSDDGKLEGCYSRPVVWFSMKNSTEVRLGQLGEDNEILLGTHRMETCQTQDYRIFVAGDIGYEFQQYVFTKKINLSEIDIIDTMIALKTEPLENIDFKVLELYSRDELAQANVFDLESIMREYNYQKKRLDFVVERVINPIPPALKGLDEMMNGMGAIGKGIGEAVGAVGGAIGSFIGALVTFVTNPFGAFVVFLFCVGCITLVITVYRRQRRAMQRPFDYFFPYASQTITSSVADSSIAVAYPGPEGTSGDAPPPYPGEAPYGYKDLSVDADTRVSSSSAGAGADFNEEDAVRMLRAIKRLDDKKRQEIEKSSKDSASNKNSETRRRPGIMDRLRRRGGYQKLNTEDDVHV
What is the function of this protein?
Envelope glycoprotein that forms spikes at the surface of virion envelope.  Essential for the initial attachment to heparan sulfate moieties of the host cell surface proteoglycans.  Involved in fusion of viral and cellular membranes leading to virus entry into the host cell.  Following initial binding to its host receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.  May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress.
What are the official names of this protein?
Envelope glycoprotein B, gB.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein B family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN).
Protein: SURE_AROAE
Sequence: MRILVSNDDGYFAPGIAALAEALQEVGDVTVVAPERDRSAASNSLTLDRPLSLRRAANGFHFVNGTPTDCVHLAVTGMLDHLPDMVVSGVNHGANMGDDTIYSGTVAAATEGFLLGVPAIAVSLVSKAATDFSAAARVARDLAERFTRIPFQHPVLLNVNVPDRPYEELRGLRVTRLGKRHKAEPVIRSVTPRNETVYWVGAAGQAADAGEGTDFQAVAEGFVSVTPLQIDLTHNGLIPSVAEWIGR
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CARB_SALTI
Sequence: MPKRTDIKSILILGAGPIVIGQACEFDYSGAQACKALREEGYRVILVNSNPATIMTDPEMADATYIEPIHWEVVRKIIEKERPDAVLPTMGGQTALNCALELERQGVLEEFGVTMIGATADAIDKAEDRRRFDIAMKKIGLDTARSGIAHTMEEALAVAADVGFPCIIRPSFTMGGTGGGIAYNREEFEEICERGLDLSPTNELLIDESLIGWKEYEMEVVRDKNDNCIIVCSIENFDAMGIHTGDSITVAPAQTLTDKEYQIMRNASMAVLREIGVETGGSNVQFAVNPKNGRLIVIEMNPRVSRSSALASKATGFPIAKVAAKLAVGYTLDELMNDITGGRTPASFEPSIDYVVTKIPRFNFEKFAGANDRLTTQMKSVGEVMAIGRTQQESLQKALRGLEVGATGFDPKVSLDDPEALTKIRRELKDAGADRIWYIADAFRAGLSVDGVFNLTNIDRWFLVQIEELVRLEEKVTEVGITGLNADFLRQLKRKGFADARLAKLAGVREGEIRKLRDQYDLHPVYKRVDTCAAEFATDTAYMYSTYEDECEANPSVDRDKIMVLGGGPNRIGQGIEFDYCCVHASLALREDGYETIMVNCNPETVSTDYDTSDRLYFEPVTLEDVLEIVRIEKPKGVIVQYGGQTPLKLARALEAAGVPVIGTSPDAIDRAEDRERFQHAVDRLKLKQPANATVTAIEQAVEKAKEIGYPLVVRPSYVLGGRAMEIVYDEADLRRYFQTAVSVSNDAPVLLDRFLDDAVEVDVDAICDGEMVLIGGIMEHIEQAGVHSGDSACSLPAYTLSQEIQDVMRQQVQKLAFELQVRGLMNVQFAVKDNEVYLIEVNPRAARTVPFVSKATGVPLAKVAARVMAGKSLTEQGVTQEIIPPYYSVKEVVLPFNKFPGVDPLLGPEMRSTGEVMGVGRTFAEAFAKAQLGSNSTMKKQGRALLSVREGDKERVVDLAAKLLKQGFELDATHGTAIVLGEAGINPRLVNKVHEGRPHIQDRIKNGEYTYIINTTAGRRAIEDSRVIRRSALQYKVHYDTTLNGGFATTMALNADATEKVTSVQEMHAQIKKS
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: FA5V_OXYSU
Sequence: MGRYSVSPVPKCLLLMFLGWSGLKYYQVNAAQLREYRLAAQLEDWDYNPQPEELSRLSESDLTFKKIVYREYELDFKQEKPRDELSGLLGPTLRGEVGDSLIIYFKNFATQPVSIHPQSAVYNKWSEGSSYSDGTSDVERLDDAVPPGQSFKYVWNITAEIGPKKADPPCLTYAYYSHVNMVRDFNSGLIGALLICKEGSLNADGAQKFFNREYVLMFSVFDESKNWYRKPSLQYTINGFANGTLPDVQACAYDHISWHLIGMSSSPEIFSVHFNGQTLEQNHYKVSTINLVGGASVTANMSVSRTGKWLISSLVAKHLQAGMYGYLNIKDCGNPDTLTRKLSFRERRRIMKWEYFIAAEEITWDYAPEIPSSVDRRYKAQYLDNFSNFIGKKYKKAVFRQYEDSNFTKPTYAIWPKERGILGPVIKAKVRDTVTIVFKNLASRPYSIYVHGVSVSKDAEGAVYPSDPKENITHGKAVEPGQVYTYKWTVLDTDEPTVKDSECITKLYHSAVDMTRDIASGLIGPPLVCKRKALSIRGVQNKADVEQHAVFAVFDENKSWYLEDNIKKYCSNPSSVKKDDPKFYKSNVMYTLNGYASDRTEVWGFHQSEVVEWHLTSVGTVDEIVPVHLSGHTFLSKGKHQDILNLFPMSGESATVTMDNLGTWLLSSWGSCEMSNGMRLRFLDANYDDEDEGNEEEEEDDGDIFADIFNPPEVVIKKEEVPVNFVPDPESDALAKELGLFDDEDNPKQSRSEQTEDDEEQLMIASMLGLRSFKGSVAEEELKHTALALEEDAHASDPRIDSNSAHNSDDIAGRYLRTINRRNKRRYYIAAEEVLWDYSPIGKSQVRSLPAKTTFKKAIFRSYLDDTFQTPSTGGEYEKHLGILGPIIRAEVDDVIEVQFRNLASRPYSLHAHGLLYEKSSEGRSYDDNSPELFKKDDAIMPNGTYTYVWQVPPRSGPTDNTEKCKSWAYYSGVNPEKDIHSGLIGPILICQKGMIDKYNRTIDIREFVLFFMVFDEEKSWYFPKSDKSTCEEKLIGVQSRHTFPAINGIPYQLQGLMMYKDENVHWHLLNMGGPKDVHVVNFHGQTFTEEGREDNQLGVLPLLPGTFASIKMKPSKIGTWLLETEVGENQERGMQALFTVIDKDCKLPMGLASGIIQDSQISASGHVGYWEPKLARLNNTGMFNAWSIIKKEHEHPWIQIDLQRQVVITGIQTQGTVQLLKHSYTVEYFVTYSKDGQNWITFKGRHSKTQMHFEGNSDGTTVKENHIDPPIIARYIRLHPTKFYNTPTFRIELLGCEVEGCSVPLGMESGAIKDSEITASSYKKTWWSSWEPFLARLNLKGRTNAWQPKVNNKDQWLQIDLQHLTKITSIITQGATSMTTSMYVKTFSIHYTDDNSTWKPYLDVRTSMEKVFTGNINSDGHVKHFFNPPILSRFIRIIPKTWNQYIALRIELFGCEVF
What is the function of this protein?
Snake prothrombin activator that attacks the hemostatic system of prey (PubMed:6986908, PubMed:3531198).  This non-catalytic subunit is functionally similar to blood coagulation factor V (PubMed:6986908, PubMed:3531198).  It serves as a critical cofactor for the prothrombinase activity of the catalytic subunit, which is similar to the blood coagulation factor X (PubMed:6986908, PubMed:3531198).  The complex converts prothrombin to thrombin by sequential cleavage at two positions, Arg-320 followed by Arg-271 (PubMed:6986908, PubMed:3531198).  Cleavage at Arg-320 produces an active intermediate known as meizothrombin (PubMed:6986908, PubMed:3531198).  Meizothrombin is the 'second' substrate for prothrombinase, and it docks in an altered manner to present the second cleavage site (271) (PubMed:6986908, PubMed:3531198).  Cleavage at Arg-271 releases active thrombin from its pro-fragment (PubMed:6986908, PubMed:3531198).  This order of events is reversed if the protease component of prothrombinase is used on its own, suggesting that the 271 site is inherently more accessible to proteolysis (PubMed:6986908, PubMed:3531198).
What are the official names of this protein?
Venom prothrombin activator oscutarin-C non-catalytic subunit, vPA, Venom coagulation factor Va-like protein.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Secreted.
Protein: NMNA1_BOVIN
Sequence: MENSEKTEVVLLACGSFNPITNMHLRLFELAKDYMNGTGKYKVIKGIISPVGDAYKKKGLISAYHRVIMAELATKNSKWVEVDTWESLQKEWTETAKVLRHHQEKLEASICDPQQNSPVLEKPGRKRKWAEQKQDISEKKSLEQTKTKGVPKVKLLCGADFLESFGVPNLWKSEDITKILGDYGLICITRAGNDAQKFIYESDVLWKHQNNIHLVNEWITNDISSTKIRRALRRGQSIRYLVPDLVEEYIEKHNLYSSESEERNVGVVLAPLQRNTTEVKA
What is the function of this protein?
Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP (By similarity).  Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency (By similarity).  Can use triazofurin monophosphate (TrMP) as substrate (By similarity).  Also catalyzes the reverse reaction, i. e.  the pyrophosphorolytic cleavage of NAD(+) (By similarity).  For the pyrophosphorolytic activity, prefers NAD(+) and NaAD as substrates and degrades NADH, nicotinic acid adenine dinucleotide phosphate (NHD) and nicotinamide guanine dinucleotide (NGD) less effectively (By similarity).  Involved in the synthesis of ATP in the nucleus, together with PARP1, PARG and NUDT5 (By similarity).  Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming (By similarity).  Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NaADP(+) (By similarity).  Also acts as a cofactor for glutamate and aspartate ADP-ribosylation by directing PARP1 catalytic activity to glutamate and aspartate residues on histones.  Protects against axonal degeneration following mechanical or toxic insults.  Delays axonal degeneration after axotomy.  Results in a >10-fold increase in intact neurites 72 hours after injury (By similarity).
What are the official names of this protein?
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1, NMN/NaMN adenylyltransferase 1, Nicotinamide mononucleotide adenylyltransferase 1, NMN adenylyltransferase 1, Nicotinate-nucleotide adenylyltransferase 1, NaMN adenylyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic NMN adenylyltransferase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GCST_MYCTU
Sequence: MSDVPELIHGPLEDRHRELGASFAEFGGWLMPVSYAGTVSEHNATRTAVGLFDVSHLGKALVRGPGAAQFVNSALTNDLGRIGPGKAQYTLCCTESGGVIDDLIAYYVSDDEIFLVPNAANTAAVVGALQAAAPGGLSITNLHRSYAVLAVQGPCSTDVLTALGLPTEMDYMGYADASYSGVPVRVCRTGYTGEHGYELLPPWESAGVVFDALLAAVSAAGGEPAGLGARDTLRTEMGYPLHGHELSLDISPLQARCGWAVGWRKDAFFGRAALLAEKAAGPRRLLRGLRMVGRGVLRPGLAVLVGDETVGVTTSGTFSPTLQVGIGLALIDSDAGIEDGQQINVDVRGRAVECQVVCPPFVAVKTR
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: UCRI_AOTAZ
Sequence: MLSVAARSGPFAPVLSATSRGVAXXXXXXXXXXXXXTPQPPVLDPKRPILSRESLSGQAARRPLVATVGLNVPASVRYSHTDIKVPDFSDYRRSEVLDTTKSSRESSDARKGFSYLVTATTAVGVTYAAKSIVTQFVSSMSASADVLAMSKIEIKLSDIPEGKNMAFKWRGKPLFVRHRTQKEIEQEAAVELSQLRDPQHDLDRVKKPEWMILIGVCTHLGCVPIANAGDFGGYYCPCHGSHYDASGRIRKGPAPLNLEVPTYEFTSDDLVIVG
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).  UQCRFS1 undergoes proteolytic processing once it is incorporated in the complex III dimer.  One of the fragments, called subunit 9, corresponds to its mitochondrial targeting sequence (MTS) (By similarity).  The proteolytic processing is necessary for the correct insertion of UQCRFS1 in the complex III dimer, but the persistence of UQCRFS1-derived fragments may prevent newly imported UQCRFS1 to be processed and assembled into complex III and is detrimental for the complex III structure and function (By similarity).
What are the official names of this protein?
Cytochrome b-c1 complex subunit Rieske, mitochondrial, Complex III subunit 5, Cytochrome b-c1 complex subunit 5, Rieske iron-sulfur protein, RISP, Rieske protein UQCRFS1, Ubiquinol-cytochrome c reductase iron-sulfur subunit.
What is the protein family that this protein belongs to?
Belongs to the Rieske iron-sulfur protein family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.