PharMolix/UniProtQA huggingface dataset:
Protein: SUGPH_MYCTU
Sequence: MGVRNHRLLLLRHGETAWSTLGRHTGGTEVELTDTGRTQAELAGQLLGELELDDPIVICSPRRRTLDTAKLAGLTVNEVTGLLAEWDYGSYEGLTTPQIRESEPDWLVWTHGCPAGESVAQVNDRADSAVALALEHMSSRDVLFVSHGHFSRAVITRWVQLPLAEGSRFAMPTASIGICGFEHGVRQLAVLGLTGHPQPIAAG
What is the function of this protein?
Phosphatase with a broad specificity.  Can dephosphorylate a variety of substrates including phosphorylated sugars like fructose-6-phosphate (F6P) (PubMed:16672613).  Is able to function in vivo as a fructose-1,6-bisphosphatase (FBPase) and to maintain gluconeogenesis when the classical FBPase GlpX is absent (PubMed:26258286).  Shows negligible phosphoglycerate mutase activity (PubMed:16672613).  Has no phosphatase activity against 3-phosphoglycerate, 2,3-bisphosphoglycerate, or hydrophobic substrates such as alpha-napthyl phosphate (PubMed:16672613).
What are the official names of this protein?
Acid phosphatase, Broad-specificity phosphatase, Fructose-1,6-bisphosphatase, FBPase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family.
Protein: MECA1_HALH5
Sequence: MRLERLAVNKIKVFLTFDDLKERGITKDELWQDIPKVHDLFRDMMLEADDELGFKADGPIAVEVFALPAQGMVIIVTKGHQESDFDEDGLEDGYIEMQVTLDESDEVFYEFADIEDVISLVPRLVTLGMTGGTLYSYQGRYYISFTDLDLDGIDEESLIALLAEYGYPSTISTYRVAEYGSLIIANDACIKLYQSFFKART
What is the function of this protein?
Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.  Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease.  When overexpressed, inhibits sporulation.  Also involved in Spx degradation by ClpC (By similarity).
What are the official names of this protein?
Adapter protein MecA 1.
What is the protein family that this protein belongs to?
Belongs to the MecA family.
Protein: ATX3_HUMAN
Sequence: MESIFHEKQEGSLCAQHCLNNLLQGEYFSPVELSSIAHQLDEEERMRMAEGGVTSEDYRTFLQQPSGNMDDSGFFSIQVISNALKVWGLELILFNSPEYQRLRIDPINERSFICNYKEHWFTVRKLGKQWFNLNSLLTGPELISDTYLALFLAQLQQEGYSIFVVKGDLPDCEADQLLQMIRVQQMHRPKLIGEELAQLKEQRVHKTDLERVLEANDGSGMLDEDEEDLQRALALSRQEIDMEDEEADLRRAIQLSMQGSSRNISQDMTQTSGTNLTSEELRKRREAYFEKQQQKQQQQQQQQQQGDLSGQSSHPCERPATSSGALGSDLGDAMSEEDMLQAAVTMSLETVRNDLKTEGKK
What is the function of this protein?
Deubiquitinating enzyme involved in protein homeostasis maintenance, transcription, cytoskeleton regulation, myogenesis and degradation of misfolded chaperone substrates (PubMed:12297501, PubMed:17696782, PubMed:23625928, PubMed:28445460, PubMed:16118278).  Binds long polyubiquitin chains and trims them, while it has weak or no activity against chains of 4 or less ubiquitins (PubMed:17696782).  Involved in degradation of misfolded chaperone substrates via its interaction with STUB1/CHIP: recruited to monoubiquitinated STUB1/CHIP, and restricts the length of ubiquitin chain attached to STUB1/CHIP substrates and preventing further chain extension (By similarity).  Interacts with key regulators of transcription and represses transcription: acts as a histone-binding protein that regulates transcription (PubMed:12297501).  Regulates autophagy via the deubiquitination of 'Lys-402' of BECN1 leading to the stabilization of BECN1 (PubMed:28445460).
What are the official names of this protein?
Ataxin-3, Machado-Joseph disease protein 1, Spinocerebellar ataxia type 3 protein.
What are the subcellular locations of this protein?
Nucleus matrix. Nucleus. Note=Predominantly nuclear, but not exclusively, inner nuclear matrix.
Protein: YABA_ALKCK
Sequence: MDKKAIFTQVSSLEERIGDLHDELRGLKEQLAYLIEENHYLHVENENLRKRLEPEAGTKNTVTPSGESSRKKMVGEGHENLARLYQEGFHICNTHYGSIRPEGDDCLFCLSFLHQK
What is the function of this protein?
Involved in initiation control of chromosome replication.
What are the official names of this protein?
Initiation-control protein YabA.
What is the protein family that this protein belongs to?
Belongs to the YabA family.
Protein: TYSY_STAAU
Sequence: MYNPFDEAYHGLCEEILEIGNRRDDRTHTGTISKFGHQLRFDLTKGFPLLTTKKVSFKLVATELLWFIKGDTNIQYLLKYNNNIWNEWAFENYVQSDDYHGPDMTDFGHRSQQDPEFNEQYKEEMKKFKERILNDDAFAKKYGNLGNVYGKQWRDWEDKNGNHYDQLKSVIQQIKTNPNSRRHIVSAWNPTEIDSMALPPCHTMFQFYVQEGKLNCQLYQRSADIFLGVPFNIASYALLTHLVAKECGLEVGEFIHTFGDAHIYSNHMDAIHTQLSRDSYLPPQLKINTDKSIFDINYEDLELINYESHPAIKAPIAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPXT_PAUCH
Sequence: MSASLSQLVHQLSARFNNQQQAFDNPPLYAHIVVNCRPLVHLLPGSLLIEQSYAMDPLKPYRIRVLRAQTRDEKLIIFSYSLSDEQKYWGSVYEPERMLKIEEKDLQAIEGCNYIVRKKNSNFIGEVEPGCRCLVDRKGVTTYIVSKFELTNKGEMRTLDRGHNPVTHEQLWGSLGGVFEFNRTTDFSKEIPYDWIEEWKK
What is the function of this protein?
Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins.
What are the official names of this protein?
Chromophore lyase CpcT/CpeT.
What is the protein family that this protein belongs to?
Belongs to the CpcT/CpeT biliprotein lyase family.
What are the subcellular locations of this protein?
Plastid, organellar chromatophore.
Protein: Y1364_STRP2
Sequence: MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRARLPVKLIYAQGFASKEEAMSAEALFKRKKRPQKEEFLSENQDRNLLSYFEESWGVL
What are the official names of this protein?
UPF0213 protein SPD_1364.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: ZCC18_MOUSE
Sequence: MASLLARMGNSRRQNAAFMPFAHSMLRALGRSLGPLIANIAERNIQSFSGRAELGPGEETFENWLSQVHEVLPDWPMSEEEKIKRLMRTLRGPAREAMRLFQADNPNLNVAEFLRAMKLLFGASESSITAHGKFLSTLQAQGEKPSLYVIRLEVQLQNAIQAGVLPQSEANRTRLHQLLVGAELSRELRTKLKGLLQMHAHNEQENLPDFLELIRMIREEEDWDETFLRNKRPRRSETVMERAASPVVFQGSLPIVIGSADCNVIEIDDSQDDSDEDVILVEPEDPPLSSPGASSLRGTASTQEEMLIIESPDDFDEESPSTSSGSGQRNNGPGDLGRTRKRKYPIRCPHCGEEGHAKETCDNTSNKGQVFENLIVTLQELTHMERPKPSVPY
What are the official names of this protein?
Zinc finger CCHC domain-containing protein 18.
What is the protein family that this protein belongs to?
Belongs to the ZCCHC12 family.
Protein: EPB41_CANLF
Sequence: MTTEKSLVAEAENSQHQQQKEEGEGVTNSGQQETQLEELSQEAAEGDNHCEQKLKTSNGDTPTHEDLTKNKERTSENRGLSRLFSSFLKRPKSQVSEEEGKDVESAKEKCEGGQKEIEFGTSLDEEIILKAPIAAPEPELKTDPSLDLHSLSSAETQPAQEEHREDPDFETKEGGGLEECSKIEVKEESPESKAERELKASQKSIRRHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAIWDNGASKTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVSGRLPCSFATLALLGSYTIQSELGDYDPELHGAEYVSDFKLAPNQTKELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTSTDTLPKSKFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKRASRSLDGAAAVDSDRSPRPTSAPAIAQSQDAEGTVPGAPVKKTVVSKAQKETVKDEEKKEEGPPDQAEPEPTEVWKDLDKSQEEIKKHHASISELKKNFMESVPEPRPSEWDKRLSTHSPFRTLNINGQLPTGEGPPLVKTQTVTISDTANSVKSEIPTKDVPIVHTETKTITYEAAQTDDSNGDLDPGVLLTAQTITSETTSSTTTTQITKTVKGGISETRIEKRIVITGDADIDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEISEE
What is the function of this protein?
Protein 4. 1 is a major structural element of the erythrocyte membrane skeleton.  It plays a key role in regulating membrane physical properties of mechanical stability and deformability by stabilizing spectrin-actin interaction.  Recruits DLG1 to membranes.  Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase.
What are the official names of this protein?
Protein 4.1, P4.1, 4.1R, Band 4.1, Erythrocyte membrane protein band 4.1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton. Cytoplasm, cell cortex.
Protein: RRAA_SALCH
Sequence: MKYDTSELCDIYQEDVNVVEPLFSNFGGRSSFGGQIITVKCFEDNGLLYDLLEQNGRGRVLLVDGGGSIRRALVDAELARLATQNEWEGLVIYGAVRQVDDLEELDIGIQAIAAIPVGAAGEGIGESDVRVNFGGVTFFSGDHLYADNTGIILSEDPLDIE
What is the function of this protein?
Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity.  Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.  Modulates RNA-binding and helicase activities of the degradosome.
What are the official names of this protein?
Regulator of ribonuclease activity A.
What is the protein family that this protein belongs to?
Belongs to the RraA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SARU_STAAU
Sequence: MDYQTFEKVNKFINVKAYIFFLTQELKQQYKLSLKELLILAYFYYKNEHSISLKEIIGDILYKQSDVVKNIKSLSKKGFINKSRNEADERRIFVSVTPIQRKKIACVINELDKIIKGFNKERDYIKYQWAPKYSKEFFILFMNIMYSKDFLKYRFNLTFLDLSILYVISSRKNEILNLKDLFESIRFMYPQIVRSVNRLNNKGMLIKERSLADERIVLIKINKIQYNTIKSIFTDTSKILKPRKFFF
What is the function of this protein?
Positive regulator of RNAII and RNAIII in a cell density-dependent manner.  It can contribute to the expression of virulence genes controlled by agr.  May also regulate target genes via an agr-independent pathway (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator SarU, Staphylococcal accessory regulator U.
What is the protein family that this protein belongs to?
Belongs to the SarA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSPQ_ECOLU
Sequence: MIASKFGIGQQVRHSLLGYLGVVVDIDPVYSLSEPSPDELAVNDELRAAPWYHVVMEDDNGLPVHTYLAEAQLSSELQDEHPEQPSMDELAQTIRKQLQAPRLRN
What is the function of this protein?
Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress.
What are the official names of this protein?
Heat shock protein HspQ.
What is the protein family that this protein belongs to?
Belongs to the HspQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S26A2_BUBBU
Sequence: MSLKNEEQNDLSPKDSVKGNDQYRAPSGIHLEREEESRNDFWQFEPSNLFRHPRIHLEPQEKSDNNFKKFVIKKLEKSCQCSSTKAKNTIFGFLPVLQWLPKYDLKKNILGDVMSGLIVGILLVPQSIAYSLLAGQEPIYGLYTSFFASLIYFILGTSRHISVGIFGILCLMIGEVVDRELYIAGYDAVHAASNESSLVNQMPDKTCDRSCYAIIVGSTVTFVAGVYQVAMGFFQVGFVSVYLSDALLGGFVTGASFTILTSQVKYLLGLSLPRSAGVGSLITTWIHVFRNIHKTNICDLITSLLCLLVLLPTKELNERFKSKLKAPIPVELFVVVAATLASHFGKLNEKYGTSIAGHIPTGFMPPEAPDWNLIPRVAIDAIAIAIIGFAITVSLSEMFAKKHGYTVKANQEMYAIGFCNIIPSFFHCFTTSAALAKTLVKESTGCQTQVSGVMTALVLLLVLLVIAPLFFSLQKSVLGVITIVNLRGALCKFKDLPQMWRISRMDTVIWFVTMLSSALISTEIGLLTGVCFSMFCVILRTQKPKASLLGLVEDSEVFESMSAYKNLQAKSGIKIFRFVAPLYYVNKEYFKSVLYKKTLNPVLVKAAQRKAAKRKIKRETVTPSGIQDEVSVQLSHDPLEFHTIVIDCSAIQFLDTAGIHTLKEVRRDYEAIGIQVLLAQCNPSVRTPGRGEYCKKDEENLLFYSVYEAMTFAEDSQNQKETYVPNGPNFSSD
What is the function of this protein?
Sulfate transporter.  May play a role in endochondral bone formation.
What are the official names of this protein?
Sulfate transporter, Solute carrier family 26 member 2.
What is the protein family that this protein belongs to?
Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TIM23_XENLA
Sequence: MDTNHPGSAGGRGGLGSIFGGGPPGYSHSDLAGVPLTGMSPLSPYLNVDPMYLVQDTDEFILPTGANKTRGRFELAFFTIGGCCISGAAFGALNGLKLGFKETQNMPWSKPKNVQILNMVTRQGALWANTLGSLALLYSAFGVIVEKTRGAEDDLNTIAAGTMTGMLYKSTGGLRGVARGGLAGLALASTFALYNNWEHIKGSSSQVSL
What is the function of this protein?
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit Tim23.
What is the protein family that this protein belongs to?
Belongs to the Tim17/Tim22/Tim23 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NU4LM_ZAGBR
Sequence: MTTMFFNLLLAFMVALMGVYIYREHLMSTLLCLEGMMLSIFIMVSLTLLHHHLNSTMMFPLILLVFSACEAGVGLALLVKTSNSYGTDYIDNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: HEM6_SHEWM
Sequence: MSVPDVSVVKAFLLDLQQRICDGLEQLDGEAKFKADSWKREEGGGGTSRVLTQGKVFEQAGVNFSHVTGAAMPASATAHRPELAGRSFEAMGVSLVIHPNNPYIPTTHANVRFFIAKKEGADPVWWFGGGFDLTPYYPFKEDVIEWHQNAHDLCLPFGEEVYPKYKKWCDDYFYLPHRDETRGVGGLFFDDLNAEGFDTSFAFMQAVGNGFLTAYAPIVQRRKETQYGEREREFQLYRRGRYVEFNLVYDRGTLFGLQTGGRTESILMSMPPLVRWEYMYTPEENSPESLLYSDYLTPKDWLSLNK
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERA_YERPG
Sequence: MSEVEKTYCGFIAIVGRPNVGKSTLLNELLGQKISITSRKPQTTRHRIMGIHTEGPYQAIYVDTPGLHIEEKRAINRLMNRAASSSLGDVELVIFVVEGTHWTADDEMVVNKLRSLQCPVLLAINKVDNVTDKTKLLPHMQFLSQQMNFLDVVPISAEKGMNVDTIASIVRKHMPEAEHHFPEDYITDRSQRFMASEIIREKLMRFLGEELPYSVTVEIEQFVPNERGGYNIHGLILVEREGQKKMVIGNKGSKIKVIGTEARQDMERMFEAKVHLELWVKVKSGWADDERALRSLGYTDDLK
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: STP7_ARATH
Sequence: MAGGSFGPTGVAKERAEQYQGKVTSYVIIACLVAAIGGSIFGYDIGISGGVTSMDEFLEEFFHTVYEKKKQAHESNYCKYDNQGLAAFTSSLYLAGLVSTLVASPITRNYGRRASIVCGGISFLIGSGLNAGAVNLAMLLAGRIMLGVGIGFGNQAVPLYLSEVAPTHLRGGLNMMFQLATTIGIFTANMVNYGTQQLKPWGWRLSLGLAAFPALLMTLGGYFLPETPNSLVERGLTERGRRVLVKLRGTENVNAELQDMVDASELANSIKHPFRNILQKRHRPQLVMAICMPMFQILTGINSILFYAPVLFQTMGFGGNASLYSSALTGAVLVLSTFISIGLVDRLGRRALLITGGIQMIICQVIVAVILGVKFGDNQELSKGYSVIVVIFICLFVVAFGWSWGPLGWTIPSEIFPLETRSAGQSITVAVNLLFTFIIAQAFLGLLCAFKFGIFLFFAGWVTVMTIFVYFLLPETKGVPIEEMTLLWSKHWFWKKVLPDATNLEDESKNVSV
What is the function of this protein?
Mediates an active uptake of hexoses, probably by sugar/hydrogen symport.
What are the official names of this protein?
Sugar transport protein 7, Hexose transporter 7.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RRT8_YEAST
Sequence: MKAGIELISHSQASHATYANSMTLAEKGPQRLKRQFKEHSSSKESNVSRWLKIFIRQFDIWFPETIPTMKVRYELLRKNFIKEIFNSRAFIYPFLGFYEVLTNPVYWKHILLFAVCYALIFVTIAGLFYVTLVPLLVTWAILLLGPLGVILVHIQWILQTNVLTAFVCRTLVLTHITNQIFDISLVLQDQDEFLNEVKVLPKPQKPHRKIDEPDAVRNFNTIKGSRIFKIPRLLFRMFFKVSNFTSLTLLSLIPIVGPILANQLMAPKRTFTYLQRYFLLKGFSKKQAKDFQYEHYASFICFGMSAGLLELIPFFTIVTISSNTVGAAKWCTSLLKGERKKE
What is the function of this protein?
Involved in spore wall assembly (PubMed:23966878).  May be involved in the modulation of rDNA transcription (PubMed:19270272).
What are the official names of this protein?
Outer spore wall protein RRT8, Regulator of rDNA transcription protein 8.
What is the protein family that this protein belongs to?
Belongs to the LDS family.
What are the subcellular locations of this protein?
Prospore membrane; Multi-pass membrane protein. Lipid droplet. Spore wall. Note=Localizes to the ascal side of growing prospore membranes in mid-meiosis II and to the spore wall in post-meiotic cells. Localizes to a specific subset of lipid droplets associated with the exterior surface of the spore throughout spore wall formation.
Protein: MSA2_PLAF2
Sequence: MKVIKTLSIINFFIFVTFNIKNESKYSNTFINNAYNMSIRRSMAESKPPTGDGAVASAGNGAVASAGNGAVASAGNGAVASAGNGAGNGAGNGAGNGAGNGAGNGAGNGAGNGAGNGAGNGAGNGAGNGAGNGAGNGAGNGAGNGAVASAGNGAGNGAVASAGNGAVAERSSSTPATTTTTTTTNDAEASTSTSSENSNHNNAETNPKGNGEVQPNQANKETQNNSNVQQDSQTKSNVPRTQDADTKSPTAQPEQAENSAPTAEQTESPELQSAPENKGTGQHGHMHGSRNNHPQNTSDSQKECTDGNKENCGAATSLLNNSSNIASINKFVVLISATLVLSFAIFI
What is the function of this protein?
May play a role in the merozoite attachment to the erythrocyte.
What are the official names of this protein?
Merozoite surface protein 2, Merozoite surface antigen 2, MSA-2.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: BLH2_ARATH
Sequence: MGITKTSPNTTILLKTFHNNSMSQDYHHHHHHNQHQGGIFNFSNGFDRSDSPNLTTQQKQEHQRVEMDEESSVAGGRIPVYESAGMLSEMFNFPGSSGGGRDLDLGQSFRSNRQLLEEQHQNIPAMNATDSATATAAAMQLFLMNPPPPQQPPSPSSTTSPRSHHNSSTLHMLLPSPSTNTTHHQNYTNHMSMHQLPHQHHQQISTWQSSPDHHHHHHNSQTEIGTVHVENSGGHGGQGLSLSLSSSLEAAAKAEEYRNIYYGANSSNASPHHQYNQFKTLLANSSQHHHQVLNQFRSSPAASSSSMAAVNILRNSRYTTAAQELLEEFCSVGRGFLKKNKLGNSSNPNTCGGDGGGSSPSSAGANKEHPPLSASDRIEHQRRKVKLLTMLEEVDRRYNHYCEQMQMVVNSFDIVMGHGAALPYTALAQKAMSRHFRCLKDAVAAQLKQSCELLGDKDAAGISSSGLTKGETPRLRLLEQSLRQNRAFHQMGMMEQEAWRPQRGLPERSVNILRAWLFEHFLHPYPSDADKHLLARQTGLSRNQVSNWFINARVRLWKPMVEEMYQQESKEREREEELEENEEDQETKNSNDDKSTKSNNNESNFTAVRTTSQTPTTTAPDASDADAAVATGHRLRSNINAYENDASSLLLPSSYSNAAAPAAVSDDLNSRYGGSDAFSAVATCQQSVGGFDDADMDGVNVIRFGTNPTGDVSLTLGLRHAGNMPDKDASFCVREFGGF
What is the function of this protein?
Transcription factor that establishes leaf shape by repressing growth in specific subdomains of the leaf.  Negatively regulates knox homeobox gene KNAT1/BP expression.
What are the official names of this protein?
BEL1-like homeodomain protein 2, BEL1-like protein 2, Protein SAWTOOTH 1.
What is the protein family that this protein belongs to?
Belongs to the TALE/BELL homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HUTG_STRPB
Sequence: MLEDYYPSTTSYYHGGIDDDLYTAKWGMVMTFLDLNDSSLTPFEGTHFALIGFKSDKGVYINNGRVGAVESPAAIRTQLAKFPWHLGNQVMVYDVGNIDGPNRSLEQLQNSLSKAIKRMCDLNLKPIVLGGGHETAYGHYLGLRQSLSPSDDLAVINMDAHFDLRPYDQTGPNSGTGFRQMFDDAVADKRLFKYFVLGIQEHNNNLFLFDFVAKSKGIQFLTGQDIYQMGHQKVCRAIDRFLEGQERVYLTIDMDCFSVGAAPGVSAIQSLGVDPNLAVLVLQHIAASRKLVGFDVVEVSPPHDIDNHTANLAATFIFYLVQIMAQHS
What is the function of this protein?
Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.
What are the official names of this protein?
Formimidoylglutamase, Formiminoglutamase, Formiminoglutamate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: LGB2_SOYBN
Sequence: MGAFTEKQEALVSSSFEAFKANIPQYSVVFYTSILEKAPAAKDLFSFLSNGVDPSNPKLTGHAEKLFGLVRDSAGQLKANGTVVADAALGSIHAQKAITDPQFVVVKEALLKTIKEAVGDKWSDELSSAWEVAYDELAAAIKKAF
What is the function of this protein?
Provides oxygen to the bacteroids.  This role is essential for symbiotic nitrogen fixation.
What are the official names of this protein?
Leghemoglobin C2.
What is the protein family that this protein belongs to?
Belongs to the plant globin family.
Protein: PG045_VACCA
Sequence: MLSMFMCNNIVDYVDGIVQDIEDEASNNVDHDYVYPLPENMVYRFDKSTNILDYLSTERDHVMMAVRYYMSKQRLDDLYRQLPTKTRSYIDIINIYCDKVSNDYNRDMNIMYDMASTKSFTVYDINNEVNTILMDNKGLGVRLATISFITELGRRCMNPVKTIKMFTLLSHTICDDCFVDYITDISPPDNTIPNTSTREYLKLIGITAIMFATYKTLKYMIG
What is the function of this protein?
Plays a role in evading host innate immune response by inhibiting host inflammasome activation.  Interacts with and inhibits NLR-mediated interleukin-1 beta/IL1B production in infected cells.  At the host mitochondria outer membrane, interacts with the BH3 domain of host BAK and prevents BAK from binding active BAX.  In turn, host apoptosis is inhibited.
What are the official names of this protein?
Apoptosis regulator OPG045, Protein F1.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG045 family.
Protein: G6PI_TREDE
Sequence: MEWKNLDKCTSFTQLQKAHKEQAENLKLADIFDTENSVKRVKNYSVKMGGNLKYNYAAKPVNDEILKALQSLADEQKLIEKYELLLNGDFINTGENRMVLHQLTRGQLKNDVVYKGVNMRSFYLNELKKIKEFSEAVHSGKIKTSQGKVFTDVVQIGIGGSDLGPRAMYIALKNRAKKKMRAHFISNVDPDDAAEVLNSINLASTLFILVSKSGTTQETLANERFVKSVLEKNGLDCKKQMLAVTSETSPLANNPDYLTSFYMDDFIGGRYSSTSVCGAAVLALAFGMETVEAFLKGAAEGDKLSLNKNIKENASLLDALLGVYERNILGCSATAILPYSQALSRFPAHLQQLDMESNGKTVNRFGEKVSYKTGPVIFGEPGTNGQHSFYQLLHQGSDIIPLQFIGFKKSQIGLDIESEGSTNMQKLNANLAAQIMAFAAGKTDENKNKDFAGNRPASLIYGEELNPENLGALLAHYENKVMFQGFIWNLNSFDQEGVQLGKTLAKKVLSNDMPPALKAFSEFLL
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUF2_ASHGO
Sequence: MSSDNFPLLDIPELVTCLQECDFSLATIQNVERPSSQFVITLYKQIIDTFMGVSPDSLLEDSRNFVENGDTSEQEVYDASLVYHDTLKILALNKICYKFFLDIGVSDFNVMDLYKPDPHRTRRFLSAVANYARFREEAMLELDGDQHPDGVRYLEQTDKLLKELRLKFDANNLLHSRVQKYKEFQKSDDLEALESDNKNMESELRHLNQVQETLTVDYERYKAEKQRHLSELETLGYELIELESERDKLRKYSQTDAEVLRKGVRELSLLLEQQQVQLEKLEQKQKNLQISFETFQASTQELYEVLQIVSTDLQDSHLKESTLLDAKHKLMQNHKNLNNLLSAGIMAKITLLQEQLDSQKRKLAELELNTQAKESENSATLKRLRKQHTDDVLPEVRNIEQRYKTKVADTITNYESQMRNIKVDFDNEVALIENECSLLFNHIKNYMTTIGEKLG
What is the function of this protein?
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
What are the official names of this protein?
Probable kinetochore protein NUF2.
What is the protein family that this protein belongs to?
Belongs to the NUF2 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with kinetochores.
Protein: LEUC_ACIC5
Sequence: MAKTLFEKVWEQHLVAEPANEPALLYIDLHLVHEVTSPQAFDGLRMTGRKLRRPDRTVATVDHNVPTIAADRLIIKDEIAARQIDALRRNCAEFGVELFDVQSREQGIVHVIGPELGLTKPGMTIVCGDSHTSTHGAFGALAFGIGTSEVEHVMATQCLPQGRPKTFRISVEGELPEGVTAKDIVLGIIGRIGTDGATGYVIEYAGSAIRSLSMEGRMTVCNMSIEAGARAGMIAPDETTFAYLKDREYSPKGKAWDEAVAAWSELKTDEGATFDRELVIPAIELTPYVTWGTNPGMVIPITDEIPGPETAASEADQRGIERALEYMGLKPGTPMEEVAIDVVFIGSCTNSRIEDLRAAAKVVTGYRVNEKVRAMVVPGSHRVKEQAEREGLDRIFREAGFEWREPGCSMCLGMNPDILTPGERCASTSNRNFEGRQGRGGRTHLVSPMMAAAAAITGHFSDIRTWEFKGEEVLA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: AZOR_SALTI
Sequence: MSKVLVLKSSILAGYSQSGQLTDYFIEQWREKHVADEITVRDLAANPVPVLDGELVGAMRPGDAPLTPRQQDALALSDELIAELKAHDVIVIAAPMYNFNIPTQLKNYFDLIARAGITFRYTEKGPEGLVTGKRAVVLSSRGGIHKDTPTDLIAPYLKVFLGFIGITDVNFVFAEGIAYGPEVAAKAQADAKAAIDSVVAA
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.