PharMolix/UniProtQA huggingface dataset:
Protein: SYY_BURMA
Sequence: MSTDPTSKPAFPITDEVRHALAVTKRGVDELLIEEEFAQKLAKSAATGKPLRIKLGLDPTAPDIHLGHTVVLNKMRQLQDLGHTVIFLIGDFTSLIGDPSGRNATRPPLTREQIESNAKTYFEQAALVLDREKTEIRYNSEWSMPLGADGMIKLASRYTVARMLEREDFTKRFQGGIPISIHEFLYPLMQGYDSVALNADLELGGTDQKFNLLVGRELQKQYGQEQQCILTMPLLEGLDGVEKMSKSKGNYVGISEKPTDMFGKLMSISDVLMWRYFELLSFRSLDEIARFRGEAEGGRNPRDFKVMLAQEIVARFHSQADAERALEDFNHRAKGGVPDDIPAVTLAGAPLAIGQLLKQAGLVPSTSEALRNIEQGGVKIDGATVSDKALKVDAGEFVVQVGKRRFARVTLTA
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDT1_YEAST
Sequence: MIRQKIFVFIVKSRRNSICPAIRRKEDY
What are the official names of this protein?
Uncharacterized protein RDT1, Ribosomally detected transcript 1.
Protein: APAG_BORBR
Sequence: MSNRERPVKPYDLTVSVTPRYVPEQSDPSQQQYVFAYTVRITNTGSHPAQVISRHWIITDGEERVQEVRGLGVVGQQPLLAPGETFEYTSGCPLPTPIGTMRGTYHCVGENGIPFEVPIAEFLLAMPRTLH
What are the official names of this protein?
Protein ApaG.
Protein: GDT1_YEAST
Sequence: MGNMIKKASLIALLPLFTAAAAAATDAETSMESGSSSHLKSFLMSVSMIGLSEIGDKTFLIAALMAMRHKRVLVFSAAATSLAIMTILSGVVGHSAVAFLSERYTAFFAGILFLVFGYKLTMEGLEMSKDAGVEEEMAEVEEEIAIKDMNQDMDDVEKGGDTAYDKQLKNASIGKKIVHRIRELASFMFSPVWVQIFLMVFLGELGDRSQISIIAMATDSDYWYVIAGAVIGHAICSGLAVVGGKLLATRISIRTITLASSLLFFIFALMYIYQAFTTQD
What is the function of this protein?
May be involved in ribosome biogenesis.  Has also been proposed to play a role in calcium homeostasis (PubMed:23569283).
What are the official names of this protein?
GCR1-dependent translation factor 1.
What is the protein family that this protein belongs to?
Belongs to the GDT1 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Golgi apparatus membrane.
Protein: ALCS_ASPFU
Sequence: MDTEQGLKNHTAKTSPHDETAMASLTTIPTSVTLSAEQFEKLYLSPLTQRQGMLSKQMGNPTPLALGGFVITTTPLSCCLMGWRGATGSGIAFTGPIIFLGGGLLVLTSILEFILGNTFPCVVFGTIGAFWFAFGCTMTPAFNAAAPFSTSATDTVAGLSSPDFLNTYAFLFIWMGVLMLIFLACATRTNAVYVAIFTTLTLVFGFLSGAYWRLAVADALVGNRLVVAAGACLFVASMLGFYLLVAQLFDSVGLPVRLPVGDLSRFWDRRAR
What are the official names of this protein?
Protein alcS.
What is the protein family that this protein belongs to?
Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell septum.
Protein: PPR8_ARATH
Sequence: MNLIILKRHFSQHASLCLTPSISSSAPTKQSRILELCKLGQLTEAIRILNSTHSSEIPATPKLYASLLQTCNKVFSFIHGIQFHAHVVKSGLETDRNVGNSLLSLYFKLGPGMRETRRVFDGRFVKDAISWTSMMSGYVTGKEHVKALEVFVEMVSFGLDANEFTLSSAVKACSELGEVRLGRCFHGVVITHGFEWNHFISSTLAYLYGVNREPVDARRVFDEMPEPDVICWTAVLSAFSKNDLYEEALGLFYAMHRGKGLVPDGSTFGTVLTACGNLRRLKQGKEIHGKLITNGIGSNVVVESSLLDMYGKCGSVREARQVFNGMSKKNSVSWSALLGGYCQNGEHEKAIEIFREMEEKDLYCFGTVLKACAGLAAVRLGKEIHGQYVRRGCFGNVIVESALIDLYGKSGCIDSASRVYSKMSIRNMITWNAMLSALAQNGRGEEAVSFFNDMVKKGIKPDYISFIAILTACGHTGMVDEGRNYFVLMAKSYGIKPGTEHYSCMIDLLGRAGLFEEAENLLERAECRNDASLWGVLLGPCAANADASRVAERIAKRMMELEPKYHMSYVLLSNMYKAIGRHGDALNIRKLMVRRGVAKTVGQSWIDAH
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At1g03540.
What is the protein family that this protein belongs to?
Belongs to the PPR family. PCMP-E subfamily.
Protein: VORB_METTM
Sequence: MATQMVKGNTAVIIGAMYAGCDCYFGYPITPASEILHEASRYFPLVGRKFVQAESEEAAINMVYGAAAAGHRVMTASSGPGMSLKQEGISFLAGAELPAVIVDVMRAGPGLGNIGPEQADYNQLVKGGGHGNYRNIVLAPNSVQEMCDLTMDAFELADKYRNPVIILADAVLGQMAEPLRFPERAVEHRPDTSWAVCGSRETMKNLVTSIFLDFDELEEFNFYLQEKYAAVEENEVRYEEYMVEDAEIVLVAYGISSRVAKSAVDTARADGIKVGLLRPITLFPFPSERIRELAEGGCTFISVEMSSGQMREDIKMASGCRDVELVNRMGGNLIELRDILRKIREIAGESND
What are the official names of this protein?
Ketoisovalerate oxidoreductase subunit VorB, VOR, 2-oxoisovalerate ferredoxin reductase subunit beta, 2-oxoisovalerate oxidoreductase beta chain.
Protein: KVM5_MOUSE
Sequence: DILMTQSQKFLSTSVGDRVSVTCKASQNVGTNVAWYQKKPGQSPKPLMYSASYRYSGVPDRFTGSGSGTDFTLTISNVQSEDLAEYFCQQFNRYPLTFGSGTKLELKRADAAPTVSIFPPS
What is the function of this protein?
Anti-influenza H3N2 neuraminidase antibody.
What are the official names of this protein?
Ig kappa chain V region Mem5.
What are the subcellular locations of this protein?
Secreted.
Protein: PANB_DEIRA
Sequence: MASPARVKRSLPDLTHPELTSSGAPLVMVTAYDYPGARHAEAAGVDLILVGDSLGNVVLGYDSTAPVTLADMIHHGKAVRRGAPNTFLVVDLPFGTYHAGVTDAMRHAVRVIQETGADAVKMEGSTPEVLDVVRVLSRNGVPVMGHVGLMPQTAAAQGGLRVQGKDDDSARRTLEGAVALQEAGAFAVVLEAIPARLARLISERLSVATIGIGAGVHCDGQVLVYHDLLGLYEGEEKKIAKRYADLGREAREAIAHYAAEVRAREFPSKDNSFVMKDEVLDKLY
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RFX4_MOUSE
Sequence: MHCGLLEEPDMDSTESWIERCLNESENKRYSSHTSLGNVSNDENEEKENNRASKPHSTPATLQWLEENYEIAEGVCIPRSALYMHYLDFCEKNDTQPVNAASFGKIIRQQFPQLTTRRLGTRGQSKYHYYGIAVKESSQYYDVMYSKKGAAWVSETGKREVTKQTVAYSPRSKLGTLLPDFPNVKDLNLPASLPEEKVSTFIMMYRTHCQRILDTVIRANFDEVQSFLLHFWQGMPPHMLPVLGSSTVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLDEWLKVALHDLPENLRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWRNVDLSSITKQTLYTMEDSRDEHRRLIIQLYQEFDHLLEEQSPIESYIEWLDTMVDRCVVKVAAKRQGSLKKVAQQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLYLLESLHCQERANELMRAMKGEGSTAEAQEEIILTEATPPTPSPGPSFSPAKSATSVEVPPPSSPVSNPSPEYTGLSTAGAMQSYTWSLTYTVTTAAGSPAENSQQLPCMRSTHMPSSSVTHRIPVYSHREEHGYTGSYNYGSYGNQHPHPLQNQYPALPHDTAISGPLHYSPYHRSSAQYPFNSPTSRMEPCLMSSTPRLHPTPVTPRWPEVPTANACYTSPSVHSTRYGNSSDMYTPLTTRRNSEYEHMQHFPGFAYINGEASTGWAK
What is the function of this protein?
Transcription factor that plays a role in early brain development.  May activate transcription by interacting directly with the X-box.  May activate transcription from CX3CL1 promoter through the X-box during brain development.
What are the official names of this protein?
Transcription factor RFX4, Regulatory factor X 4.
What is the protein family that this protein belongs to?
Belongs to the RFX family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CWC2_CRYNB
Sequence: MSSDNTVAPKRKLKPARKQVASDEVDKSQGYQAGREYNIWYNKWAGGDREDALASKVHSQTRCIISRDAGYTRADATGNKYCCLFFARGCCPYGYECQYLHRLPLPSHQLPDNSRDCFGREKHADYRDDMGGVGSFNRQNRTLYIGKIQESPDKKQMTETLLRHFGEWGKIVKYNILFGRGVAFVTYETDHQASFAKEAMANQSMDGDEILNVRWATEDPNPGEKVAEEKRIEEIGQKAIAGMLDENLVEATQAVRALEDGDVEDFYHIETSKPEEEEENRPAKKGKSEGGFFNADALDNIKFYAELAKKQAEEEKEKARKVPAKQVGMSLLGGYGSGDESD
What is the function of this protein?
Involved in the first step of pre-mRNA splicing.  Required for cell growth and cell cycle control.  Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the maintenance of the U4/U6 snRNA complex.  May provide the link between the 'nineteen complex' NTC spliceosome protein complex and the spliceosome through the U6 snRNA.  Associates predominantly with U6 snRNAs in assembled active spliceosomes.  Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle (By similarity).
What are the official names of this protein?
Pre-mRNA-splicing factor CWC2.
What is the protein family that this protein belongs to?
Belongs to the RRM CWC2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GATA_STRU0
Sequence: MSLNHKTIDELHTLLLSKEISAKELTQATLDDIKAREDAVGSFITLAEEKALSQAEAIDARGIDPNNVMSGIPFAVKDNISTEGILTTAASKMLYNYEPIFNATAIEKAYAKDMIVIGKTNMDEFAMGGSTETSYFKKTKNAWDHSKVPGGSSGGSATAVASGQVRLSLGSDTGGSIRQPAAFNGIVGMKPTYGTVSRFGLIAFGSSLDQIGPFSQTVKENAQLLNVIAGSDDKDSTSAPVQIADYTSAIGKDIKGMKIALPKEYLGEGIDPKIKENILEAAKQFEKLGATVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAQDAKTLEEIYVNTRSQGFGEEVKRRIMLGTFSLSSGYYDAYFKKAGQVRTLIIQDFEKVFADYDLIIGPTAPTVAFGLDTLNHDPVSMYLADLLTIPVNLAGLPGISIPSGFVDGLPVGLQLIGPKYSEERIYQAAAAFEATTDYHKQQPVIFGGEK
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: TCS2_CAMSI
Sequence: MKEVKEALFMNKGEGESSYAQNSSFTQTVTSMTMPVLENAVETLFSKDFHLLQALNAVDLGCAAGPTTFTVISTIKRMMEKKCRELNCQTLELQVYLNDLPGNDFNTLFKGLPSKVVGNKCEEVSCYVVGVPGSFHGRLFPRNSLHLVHSCYSVHWLTQAPKGLTSKEGLALNKGKIYISKTSPPVVREAYLSQFHEDFTMFLNSRSQEVVPNGCMVLILRGRLSSDPSDMGSCFTWELLAVAIAELVSQGLIDEDKLDTFNVPSYFPSLEEVKDIVERNGSFTIDHMEGFELDSPEMQENDKWVRGEKFATVARAFTEPIISNQFGHEIMDKLYEKFTHIVVSDFEAKIPKITSIILVLSKIVG
What is the function of this protein?
May be involved in the biosynthesis of caffeine (By similarity).  Catalyzes the conversion of 7-methylxanthine (7mX) to theobromine and of theobromine to caffeine (By similarity).  Has 1-N-methylation activity (By similarity).
What are the official names of this protein?
Probable caffeine synthase 2.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Type-7 methyltransferase family.
Protein: MPT53_MYCBO
Sequence: MSLRLVSPIKAFADGIVAVAIAVVLMFGLANTPRAVAADERLQFTATTLSGAPFDGASLQGKPAVLWFWTPWCPFCNAEAPSLSQVAAANPAVTFVGIATRADVGAMQSFVSKYNLNFTNLNDADGVIWARYNVPWQPAFVFYRADGTSTFVNNPTAAMSQDELSGRVAALTS
What is the function of this protein?
Disulfide oxidoreductase that catalyzes the oxidation of reduced, unfolded secreted proteins to form disulfide bonds.  Despite a weak homology to thioredoxin this cannot serve as a substrate for thioredoxin reductase (By similarity).
What are the official names of this protein?
Soluble secreted antigen MPT53.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PRTV_VIBCH
Sequence: MKTIKKTLLAAAIASFFSSGLYAQTPIDLGVVNEDKLIEMLVRTGQIPADASDVDKRIALERYLEEKIRSGFKGDAQFGKKALEQRAKILKVIDKQKGPHKARVFALDVGQKRTDKVLALLIDFPDLPWDDNRLTKEHTEMLYDRYEPSHYQDLLFSDKGYTGPNGENFISMRQYYESESGNSYSVSGQAAGWYRASKNAAYYGGNSPGTNNDMNARELVREALDQLARDPNINLADYDIEDRYDYNGNGNFREPDGVIDHLMIFHASVGEEAGGGVLGADAIWSHRFNLGRYHVLEGTKSNVPGRFNGQFAAFDYTIQPIDAAAGVCAHEYGHDLGLPDEYDTQYTGTGEPVSYWSIMSSGSWAGKIGGTQPTAFSSWAKQFLQNSIGGRWINHEQLSINELEAKPRVVTLFQTTDNSRPNMVKVTLPMKRVEGIKPAEGEFSFYSNRGDDLKNRMSRPLTIPAGSQATLRFKAWFQIEKDYDYARVLINGKPIAGNITTMDDPFKSGLVPAISGQSDGWVDAQFDLSAWAGQTVELAFDYLTDGGLAMEGLYVDDLRLEVDGNQTLIDNAEGTSSFAFQGFTKNGGFHEANHYYLLQWRSHNDVDQGLANLKRFGQLMSFEPGLLVWYVDESYADNWVGKHPGEGWLGVVDADQNALVWSKTGEVAQTRFQVRDATFSLFDQAPLKLVTADGNTLEDMNLTANASFSDDQDYSSPQAPDSGRKVMPFGLKIDLLSQSKENEYGVVRLSKVTTENIAPVARFELKVEGLSVMSQNTSSDSDGNIVSYLWDFGNGQTSTEAAPTWSYTKAGSYSVTLTVTDDKGDSDTHQQTIKVDTPNALPQASANYIHLGRWVTMWSTSTDSDGRIVDTEWTLPNGKIKRGRMFTAIFPSYGHHDVQLKVMDDRGAVTTITIKVKL
What is the function of this protein?
Metalloprotease that exhibits a cytotoxic effect leading to cell death.  In host tissues, it could play a role in pathogenesis by modulating the stability of the extracellular matrix components such as fibronectin and fibrinogen.  Also able to cleave plasminogen.
What are the official names of this protein?
Pre-pro-metalloprotease PrtV.
What is the protein family that this protein belongs to?
Belongs to the peptidase M6 family.
What are the subcellular locations of this protein?
Secreted.
Protein: IFI4_MOUSE
Sequence: MVNEYKRIVLLRGLECINKHYFSLFKSLLARDLNLERDNQEQYTTIQIANMMEEKFPADSGLGKLIAFCEEVPALRKRAEILKKERSEVTGETSLEKNGQEAGPATPTSTTSHMLASERGETSATQEETSTAQAGTSTAQARTSTAQAGTSTAQKRKIMREEETGVKKSKAAKEPDQPPCCEEPTARCQSPILHSSSSASSNIPSAKNQKSQPQNQNIPRGAVLHSEPLTVMVLTATDPFEYESPEHEVKNMLHATVATVSQYFHVKVFNINLKEKFTKKNFIIISNYFESKGILEINETSSVLEAAPDQMIEVPNSIIRNANASPKICDIQKGTSGAVFYGVFTLHKKTVNRKNTIYEIKDGSGSIEVVGSGKWHNINCKEGDKLHLFCFHLKTIDRQPKLVCGEHSFIKISKRGNVPKEPAKEEDHHHGPKQVMVLKVTEPFTYDLKEDKRMFHATVATETEFFRVKVFDTALKSKFIPRNIIAISDYFGCNGFLEIYRASCVSDVNVNPTMVISNTLRQRANATPKISYLFSQARGTFVSGEYLVNKKTERNKFIYYGIGDDTGKMEVVVYGRLTNVRCEPGSKLRLVCFELTSTEDGWQLRSVRHSYMQVINARK
What is the function of this protein?
Interferon-stimulated protein that plays a role in several biological processes including cell differentiation, autophagy and innate immunity (PubMed:16244109, PubMed:25710914, PubMed:30936875).  Cooperates with CGAS to sense dsDNA and activates the STING-dependent type I IFN pathway (PubMed:25710914, PubMed:33619523).  Mechanistically, gets acteylated upon bacterial infection and then translocates from nucleus into cytoplasm to recruit STING for activation of TBK1-dependent IRF3 nuclear translocation and IFN-beta release (PubMed:28529930).  Inhibits the transcription of ribosomal RNA.  May inhibit DNA binding by UBTF.  Inhibits cell growth via p53/TP53 and RB1-dependent and independent pathways.  Acts as a coactivator of RUNX2 during osteogenesis.  May be involved in macrophage differentiation.  Enables skeletal muscle and cardiac myocyte differentiation by sequestring Id proteins in the cytosol and promoting their ubiquitination and subsequent degradation.
What are the official names of this protein?
Interferon-activable protein 204, Ifi-204, Interferon-inducible protein p204.
What is the protein family that this protein belongs to?
Belongs to the HIN-200 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Cytoplasm. Note=Nuclear in proliferating cells, translocates to cytosol during cell differentiation or bacterial infection.
Protein: RPIA_BURCH
Sequence: MTQDELKRLVGQAAADYVIQNVPEGAVIGVGTGSTANCFIDALAAVKSRYRGAVSSSIATTERLKSHGIKVFDLNEIESLQVYVDGADEIDAGGAMIKGGGGALTREKIVASVADTFVCIADASKRVPVLGAFPLPIEVVPMARTAIGRRVTALGGVPVLRVTKDGAPYITDNGNEIIDVKGLQIADPRGFEAQVNAWPGVVTVGLFAERGANLCLLGTENGVETIVYPAG
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: CSM3_MYCTU
Sequence: MTTSYAKIEITGTLTVLTGLQIGAGDGFSAIGAVDKPVVRDPLSRLPMIPGTSLKGKVRTLLSRQYGADTETFYRKPNEDHAHIRRLFGDTEEYMTGRLVFRDTKLTNKDDLEARGAKTLTEVKFENAINRVTAKANLRQMERVIPGSEFAFSLVYEVSFGTPGEEQKASLPSSDEIIEDFNAIARGLKLLELDYLGGSGTRGYGQVKFSNLKARAAVGALDGSLLEKLNHELAAV
What is the function of this protein?
This subunit has the target ssRNA endonuclease activity; it cleaves multiple sites in the target RNA at 6 nucleotide intervals.
What are the official names of this protein?
CRISPR system Cms endoribonuclease Csm3, CRISPR type III A-associated RAMP protein Csm3.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated Csm3 family.
Protein: OPGC_ECO5E
Sequence: MNPVPAQREYFLDSIRAWLMLLGIPFHISLIYSSHTWHVNSAEPSLWLTLFNDFIHSFRMQVFFVISGYFSYMLFLRYPLKKWWKVRVERVGIPMLTAIPLLTLPQFIMLQYVKGKAESWPGLSLYDKYNTLAWELISHLWFLLVLVVMTTLCVWIFKRIRNNLENSDKTNKKFSMVKLSVIFLCLGIGYAVIRRTIFIVYPPILSNGTFNFIVMQTLFYLPFFILGALAFIFPHLKALFTTPSRGCTLAAALAFVAYLLNQRYGSGDAWMYETESVITMVLGLWMVNVVFSFGHRLLNFQSARVTYFVNASLFIYLVHHPLTLFFGAYITPHITSNWLGFLCGLIFVVGIAIILYEIHLRIPLLKFLFSGKPVVKRENDKAPAR
What is the function of this protein?
Necessary for the succinyl substitution of periplasmic glucans.  Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane.
What are the official names of this protein?
Glucans biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the acyltransferase 3 family. OpgC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL19_ORITI
Sequence: MNLIKQFEQEQIKKLTQGKSIPNFRPGDTVKVNLRIIEGANERIQAYQGVVIARANRSISSSFTVRKISHGQGIERKFMLYSPLISSIELIKQGVVRRAKLYYLRNLQGRKAKIREKIFSKDNQ
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: Y1765_SHEB5
Sequence: MELTLHEARVIGCLLEKEITTPEQYPLSLNSLTLACNQKTSREPVLELSETQVQIAVDSLNRKRLISEQSGFGSRVVKYKHRFCNTEFSELQLSPAALAIVCLLLLRGPQTPGELRTRSNRLHEFKDVIEVEDCIRQLMNREKPFLKQLPREAGRRESRYVELFSAASSQLETAQPESASHTVAHVAVSLDAEPLELTKRVTELEQQVAELTQKLDELIASLS
What are the official names of this protein?
UPF0502 protein Sbal_1765.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: CCA_CUPPJ
Sequence: MQVYAVGGAIRDELLGKPSQDRDYVVVGATPADMEAAGYKPVGKDFPVFLHPRTKEEYALARTERKTAMGYKGFAFYCEPDVTLDDDLVRRDLTINAMARAVDDDGKLVGPVIDPHGGQRDLAARQFRHVSEAFAEDPVRILRVARFAARFHDFTVAPETVALMRRMVDAGEVDALVPERVWQELARGLMEARPARMFEVLRQCGALARLLPELDRLWGVPQRADYHPEVDTGVHVMMVIDCAAAMGTTLAVRFAALVHDLGKGTTPEHVLPRHLGHETRSVELLEDVCKRLRVPNDCRDLAVVVAREHGNIHRSMEFGAAAITRLLERCDALRKPGRFADALLACEADKRGRKGFESDTYPQKARLLAALDAAASVDAGAIAKALADDVSKIRERVHEARVAAVDARLKQLADH
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: TIG_BURP0
Sequence: MANVVENLGKLERRVTISLPKDVVQKEIDARIQKLAKNVRMPGFRPGKVPLKMVAQQYAGQVEAEVLSDKIGQEFFTISRAENLRVAGQPSFAPKEDTQQESAYAFDATFEVYPEVKIGDLATAEVERSTTTIGDAEIDRTLDILRKQRVHFHARGEGGEHGDGGADTAAQNGDRVTVDFVGKIDGVAFQGGTAEDFVFVLGEGRMLPEFETAALGLKAGESREFDLKFPDDYHGKDVAGKTAQFTVTLKKVEWPHLPEIDADFAKSLGVEDGDLTKMRAEIKENLEREAKRRTQSIVKNQVMDALLKISELDVPKALIEQDQQRLVEMARQDLAQRGVPNAKDAPIPAEMFADQAERRVKLGLVLAELVKANGLEAKPEQIRAEVDEFAKSYEDPKEVVRWYYSNQQRLAEMEAFVVESNVVDFVLGKAKVTDKEVSFEALASATAQA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: PNP_SHESM
Sequence: MNPIVKSFEYGQHTVTLETGVIARQADAAVLASMGDTTVLVTVVGKKEAEAGRDFFPLTVNYQEKTYAAGKIPGGFFKREGRPSEDETLIARLIDRPIRPLFPNGFTNEVQVIITVVSVDPQIEPDIISMIGTSAALAISGIPFSGPLGAARVGYINGEYVLNPTVTQLANSQLNLVVAGTEGAVLMVESEAQALPEEVMLGSVVYGHDQQQVVIKAIAEFKAEAGKPAWNWTAPVANEALVAQVKELAEVGLAQAYQIQVKQERYAQVAVVKAAAKEALLAANPEVDLREVDGLLGSLEKKVVRGRIIRGEPRIDGREPDMVRALSVLAGVLPRTHGSALFTRGETQALVTCTLGTERDAQKIDSIMGERTNRFMLHYNFPPYSVGETGMVGSPKRREIGHGKLAWRGINAVMPSAEEFPYSVRVVSEITESNGSSSMASVCGTSLALMDAGVPIKTSVAGIAMGLVKEGDNFVVLSDILGDEDHLGDMDFKVAGTRDGVTALQMDIKIEGITKEIMEIALQQAYGARVHILNVMDQAIGSHRDDISDHAPRITTIKINPEKIRDVIGKGGAVIRALTEETGTTIELEDDGTVKIASSNGEATKEAIRRIEEITSEVEVGRIYNGKVIRIVDFGAFVNILPGKDGLVHISQISDERVANVSDHLELNQEVTVKVMEVDRQGRVRLSIKEAQTKEAAAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CIR1_RAT
Sequence: MGKSFANFMCKKDFHPASKSNIKKVWMAEQKISYDKKKQEELMQQYLKEQESYDNRLLMGDERVKNGLNFMYEAPPGVKKENKEKEETEGETEYKFEWQKGAPREKYAKDDMNIRDQPFGIQVRNVRCIKCHKWGHVNTDRECPLFGLSGINASSVPTDGSGPSMHPSELIAEMRNSGFALKRNVLGRNLTANDPSQDYVASDGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKKSDKKKKKLQKSKNKHKKHKKSSSSSSSSSSSSSSSSSSSSSSSSSSTSSSETDSSSESDNKEKKEKEKRKKRKKTKCSGNKSGDCKEYKSKNMLYEELSSSHSDRGKAQEKLRLLKQESSGENSTWVHSGSDRKSRSHQHSPERKGSDRNGGSRSRSRAEGSRRSRSRSPCGQKHREREARSRPHQSPSEEQKGRKGTRSHGDSEHRRERAR
What is the function of this protein?
May modulate splice site selection during alternative splicing of pre-mRNAs.  Regulates transcription and acts as corepressor for RBPJ.  Recruits RBPJ to the Sin3-histone deacetylase complex (HDAC).  Required for RBPJ-mediated repression of transcription (By similarity).
What are the official names of this protein?
Corepressor interacting with RBPJ 1, CBF1-interacting corepressor.
What are the subcellular locations of this protein?
Nucleus speckle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Colocalizes with NEK6 in the centrosome.
Protein: SYR_HALOH
Sequence: MIDFKEKLVDLISQEINDLNVEEIEHLIEIPPQPEMGDYALPCFKFAGIFKKAPNIIAEEIASKIEGNSYFSKVVNTGPYVNFFINKEIFAETVLEEILQKGKYYGARNIGKGKNVIVEFSSPNIAKPFHIGHIRTTVIGHALRNIYNFLGYNAIAINHLGDYGTQFGKLIVALNKWGDKDKIKSNPIPEFLKLYIKFHEEAEKNPELEEKARSWFNRLENKDEEAMDLWKWIRNMSLKEFKRVYDMLGIDFDSYAGESFYSDMMPDVIEEMEEKGLLQESQGAKIVDLEEYNMPPAMIEKSDGSTLYITRDIAAAIYRKKTYNFYKNIYVVGSQQKLHFDQWFKIIELMGHEWARDCIHVPFGMVSLEDGTMSTRKGRVVFLEDVLNKAIEKTKETIEDKNPDLENKEEVAKIVGIGAVIFQELYNSRIKDYVFSWDRTLSFEGETGPYVQYTYVRTKSVLNKSNYKFKKLDDYSLLTDEDAFNVIKLISQFPDTIIKASERYEPSIITRHITELAKAFNKYYHDNQILVDDQKVREARLFLVYAVNTVLKTGLSLLGIKTPEKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPD_MAGOY
Sequence: MASLGSYAKKHKVTIIGSGNWGSTIAKIVAESTREHKDVFEEDVQMWVFEEKVTIPKDSPYYESEEPQKLTEVINKHHENVKYLPGIKLPSNIIANPSLTDAVRDSSVLVFNLPHEFLGKVCQQLNGHIVPFARGISCIKGVDVSGSGINLFCEVIGEKLGIYCGALSGANVASQIAAEEGVSETTIAYDPPPIDSSRAATPRDRSPNYDSTSANKLPDLTVTSADSNGKDDRGRRTKAKLTPVPESYPPLDHGTLQILFDRPYFSVSMVSDVAGVSLSGALKNIVALAAGFVDGKGWGSNVQSAVIRVGLAEMLKFAREFFGESVDPFTILLESAGVADVITSCISGRNFRCASMAVKRGVSVAEIEEKELNGQKLQGTSTAKEVNSLLKARGREGDYPLFTTVNEILEGKARVDDLPKLVIRQKHTIEKSG
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
Protein: RS4_CAMFF
Sequence: MARYRGPVEKLERRLGVSLALKGERRLAGKSALDKRPYAPGQHGQRKTKISEYGLQLREKQKAKFMYGVSEKQFRRLFSEAARREGNTGALLIGLLEQRLDNVVYRMGFATTRRFARQLVTHGHILVNGKKVDIPSYRVTAGEKIEVAEKSKTNPQIVRAIELTNQTGIVAWVDVEKDKKYGIFTRIPEREEVVIPVEERYIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.