PharMolix/UniProtQA huggingface dataset:
Protein: ESR1_MOUSE
Sequence: MTMTLHTKASGMALLHQIQGNELEPLNRPQLKMPMERALGEVYVDNSKPTVFNYPEGAAYEFNAAAAAAAAASAPVYGQSGIAYGPGSEAAAFSANSLGAFPQLNSVSPSPLMLLHPPPQLSPFLHPHGQQVPYYLENEPSAYAVRDTGPPAFYRSNSDNRRQNGRERLSSSNEKGNMIMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDLEGRNEMGASGDMRAANLWPSPLVIKHTKKNSPALSLTADQMVSALLDAEPPMIYSEYDPSRPFSEASMMGLLTNLADRELVHMINWAKRVPGFGDLNLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHRRLAQLLLILSHIRHMSNKGMEHLYNMKCKNVVPLYDLLLEMLDAHRLHAPASRMGVPPEEPSQTQLATTSSTSAHSLQTYYIPPEAEGFPNTI
What is the function of this protein?
Nuclear hormone receptor.  The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.  Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE-independent signaling.  Ligand binding induces a conformational change allowing subsequent or combinatorial association with multiprotein coactivator complexes through LXXLL motifs of their respective components.  Mutual transrepression occurs between the estrogen receptor (ER) and NF-kappa-B in a cell-type specific manner.  Decreases NF-kappa-B DNA-binding activity and inhibits NF-kappa-B-mediated transcription from the IL6 promoter and displace RELA/p65 and associated coregulators from the promoter.  Recruited to the NF-kappa-B response element of the CCL2 and IL8 promoters and can displace CREBBP.  Present with NF-kappa-B components RELA/p65 and NFKB1/p50 on ERE sequences.  Can also act synergistically with NF-kappa-B to activate transcription involving respective recruitment adjacent response elements; the function involves CREBBP.  Can activate the transcriptional activity of TFF1.  Also mediates membrane-initiated estrogen signaling involving various kinase cascades.  Essential for MTA1-mediated transcriptional regulation of BRCA1 and BCAS3.
What are the official names of this protein?
Estrogen receptor, ER, ER-alpha, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Golgi apparatus. Cell membrane. Note=Colocalizes with ZDHHC7 and ZDHHC21 in the Golgi apparatus where most probably palmitoylation occurs. Associated with the plasma membrane when palmitoylated.
Protein: PANCY_SYNS3
Sequence: MHFVPTMGGLHHGHASLISAASCHKSGDVETLVSVFVNPLQFGPNEDFARYPRTFEADCELAELSGASAIWCPDESQIYPGGSAESWRIQAPKSLQSRLCGSTRPGHFDGVVTVVCRLLALAKPHQLFLGEKDWQQLTILRRMVLDLGLAVRVRGVPTVRDGDGLASSSRNRYLNAQQRQQGVLFAQVLSDARSACLHGGTALKPGEVKRRLEEVGLSVEYVDVVDPWFLQPSKSNQSSLTLLAAAVRCGSTRLIDHAFLMTRSPLVAIDGPAGAGKSTVTRAFAERLGLVYLDTGAMYRAVTWLVLEQGGDPGDSEAVDLVLNDLKVELEPLQQGVQVVRVNGHEVTDAIRDPRVTASVSAVASHACVRAAMTAQQQRMGKAGGLVAEGRDIGTAVFPDAELKVFLTATPKERARRRALDLEARGHEVPALPELEAQIVERDRLDSTREVAPLLQADDAIELISDGMSIDQVIDALEDLFRRRVGEEVWPTPV
What is the function of this protein?
Catalyzes the transfer of a phosphate group from ATP to either CMP or dCMP to form CDP or dCDP and ADP, respectively.
What are the official names of this protein?
Bifunctional pantoate ligase/cytidylate kinase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y434_STAAW
Sequence: MRGGGNMQQMMKQMQKMQKKMAQEQEKLKEERIVGTAGGGMVAVTVTGHKEVVDVEIKEEAVDPDDIEMLQDLVLAATNEAMNKADELTQERLGKHTQGLNIPGM
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein MW0434.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: EFTS_MYCTO
Sequence: MANFTAADVKRLRELTGAGMLACKNALAETDGDFDKAVEALRIKGAKDVGKRAERATAEGLVAAKDGALIELNCETDFVAKNAEFQTLADQVVAAAAAAKPADVDALKGASIGDKTVEQAIAELSAKIGEKLELRRVAIFDGTVEAYLHRRSADLPPAVGVLVEYRGDDAAAAHAVALQIAALRARYLSRDDVPEDIVASERRIAEETARAEGKPEQALPKIVEGRLNGFFKDAVLLEQASVSDNKKTVKALLDVAGVTVTRFVRFEVGQA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity).
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_BACC7
Sequence: MRCPSCSHNGTRVLDSRPVDEGRSIRRRRECESCLSRFTTFERVEESPLIVVKKEGTREEFNKEKILRGLIKACEKRPVSLRQLEEVTQSVERELRNLGISEVKSDMIGEIVMEELRDIDDVAYVRFASVYRQFKDLNVFIEELKDILQKERE
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: SERA_MYCLE
Sequence: MDLPVVLIADKLAQSTVAALGDQVEVRWVDGPDRTKLLAAVPEADALLVRSATTVDAEVLAAAPKLKIVARAGVGLDNVDVDAATARGVLVVNAPTSNIHSAAEHALALLLAASRQIAEADASLRAHIWKRSSFSGTEIFGKTVGVVGLGRIGQLVAARIAAFGAHVIAYDPYVAPARAAQLGIELMSFDDLLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEVALADAVRSGHVRAAGLDVFATEPCTDSPLFELSQVVVTPHLGASTAEAQDRAGTDVAESVRLALAGEFVPDAVNVDGGVVNEEVAPWLDLVCKLGVLVAALSDELPASLSVHVRGELASEDVEILRLSALRGLFSTVIEDAVTFVNAPALAAERGVSAEITTGSESPNHRSVVDVRAVASDGSVVNIAGTLSGPQLVQKIVQVNGRNFDLRAQGMNLVIRYVDQPGALGKIGTLLGAAGVNIQAAQLSEDTEGPGATILLRLDQDVPGDVRSAIVAAVSANKLEVVNLS
What is the function of this protein?
Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway.  Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.
What are the official names of this protein?
D-3-phosphoglycerate dehydrogenase, PGDH, 2-oxoglutarate reductase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
Protein: NMBR_HUMAN
Sequence: MPSKSLSNLSVTTGANESGSVPEGWERDFLPASDGTTTELVIRCVIPSLYLLIITVGLLGNIMLVKIFITNSAMRSVPNIFISNLAAGDLLLLLTCVPVDASRYFFDEWMFGKVGCKLIPVIQLTSVGVSVFTLTALSADRYRAIVNPMDMQTSGALLRTCVKAMGIWVVSVLLAVPEAVFSEVARISSLDNSSFTACIPYPQTDELHPKIHSVLIFLVYFLIPLAIISIYYYHIAKTLIKSAHNLPGEYNEHTKKQMETRKRLAKIVLVFVGCFIFCWFPNHILYMYRSFNYNEIDPSLGHMIVTLVARVLSFGNSCVNPFALYLLSESFRRHFNSQLCCGRKSYQERGTSYLLSSSAVRMTSLKSNAKNMVTNSVLLNGHSMKQEMAL
What is the function of this protein?
Receptor for neuromedin-B (PubMed:1655761).  Contributes to the maintenance of basal sigh rate through signaling in the pre-Botzinger complex, a cluster of several thousand neurons in the ventrolateral medulla responsible for inspiration during respiratory activity (By similarity).  Contributes to the induction of sneezing following exposure to chemical irritants or allergens which causes release of NMB by nasal sensory neurons and activation of NMBR-expressing neurons in the sneeze-evoking region of the brainstem (By similarity).  These in turn activate neurons of the caudal ventral respiratory group, giving rise to the sneezing response (By similarity).  Contributes to induction of acute itch, possibly through its activation on dorsal root ganglion neurons by the NMB peptide (By similarity).  Plays a role in the innate immune response to influenza A virus infection by enhancing interferon alpha expression and reducing expression of IL6 (PubMed:31601264).  Plays a role in CSF1-induced proliferation of osteoclast precursors by contributing to the positive regulation of the expression of the CSF1 receptor CSF1R (By similarity).
What are the official names of this protein?
Neuromedin-B receptor, NMB-R, Epididymis tissue protein Li 185a, Neuromedin-B-preferring bombesin receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NADD_HALHL
Sequence: MRQPLRTIGLLGGTFDPIHYGHLRPAEEVREAVQLSELRLIPARIPPHRARPRVGPEQRAELVRRAVADNPSACVDERELHRDGPSYTVDTLAELRAELGGVSLCLILGYDTFLGLPGWSRWRQLFERAHVVVTERPGVRGALPEALATEVARRVAHEPAELRHRPAGCILFQAVTPVDISATGIRRSLALGRSVRYLLPEAVRQRVVEAGWYGYPQL
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: TRM1_EHV2
Sequence: MARELAAVYAQVFDLAAEVSLLGYCDPSSIDKRCVMANSNKVFKLCESLLPCLRLQNDTECSPLSLELQHLLQNTREALGVLTDLLSGDPSRSEYFEALHPSRPLEGPCKRHARVRVPFYGGAEKTVSLSLLNDVEVFFKRLNSVFYCLPAEGALEALGETVAFLGRLRGVSPIPPADAYVSSVPCASCFAEAAMLPNQGESVLSMLAAVNCNHVCRQVPSDPVIGVFENELRHLGADARAAGRAGGGRESERRGREDADDEEDDEEEPRDGQGDAGDGAALRVLTESSLSVLAGHTIFEEEDGRLAEISNLVYWSSAADRGGVGGTARATSSSHMAKLFAHEARMHRSRAWLGRGAPSHFFDAHRPSPLESLFCGGVFNSIDDTIAALQKDCSATFLKKSNYQTLIQQQNELYVRLNEVLNGAGRDEGGAKGAEAIADAEPLKPDGGASCDPRDVLSDARVRRDLYLKKLTRDGLRRLTDCIETHGRVLSDTLSLRVWGSALYASAARLVNHFLFRRQFVGLGWADLTAGGEAAFENSKYIKNALHGQRLNREHLDSIVVHFYRLITGPLSLQNSHFPVPDNVALAYCLDAAGAMPHQKLVITEMIWPGIESKDWIDCNFNSFYSIETGDLNLTQKKTLNYIREAVLSISLYNRVWEKSLSLLSATELRGSCLAESASGELGEGVYLTYEGTAPLVLVFDSKGYVFKDLYTLLYTHLQLSGRRQASV
What is the function of this protein?
Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging.  Forms a tripartite terminase complex together with TRM2 and TRM3 in the host cytoplasm.  Once the complex reaches the host nucleus, it interacts with the capsid portal vertex.  This portal forms a ring in which genomic DNA is translocated into the capsid.  TRM1 carries an endonuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.
What are the official names of this protein?
Tripartite terminase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae TRM1 protein family.
What are the subcellular locations of this protein?
Host nucleus. Note=Found associated with the external surface of the viral capsid during assembly and DNA packaging, but seems absent in extracellular mature virions.
Protein: INGK_EXIAC
Sequence: MNKIAVIGKVFVDIKGTSFAPLHKDAKNVGDITFSNGGTGRNVAQNLAVLGNEVRFISTVTNDQIGVGVLDELKSYGANVDHVEMLEDHGMGMWLAVMDNEGDLQTSISKQPDAKLLEEAILRQSIYALDGVDAVAIDLDLSVTVLERLIHLCRKMELPLFGVCGHLSVIERNRHLLQGFTGFICSREEAEILSDLSIVTVEDAIHVANELAKKGAPFTVVTMSELGAVYVDRRTATSGHVGTKKVKVVDSTGAGDSFFSAVLSELTQEKSAEEALKLGMKVAAEVIASTENGLVPEMLDALQ
What is the function of this protein?
Catalyzes the phosphorylation of guanosine and inosine to GMP and IMP, respectively (PubMed:9357959, PubMed:11129609).  Can also use deoxyguanosine (PubMed:9357959).  Shows a strong preference for guanosine (PubMed:9357959).  dATP, GTP and dGTP can serve as phosphate donors (PubMed:9357959).
What are the official names of this protein?
Guanosine-inosine kinase, ATP:guanosine 5'-phosphotransferase, Guanosine kinase, GKase.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family.
Protein: AAT_STRVG
Sequence: MSARIGAISESATLAVDAKAKALKAAGRPVIGFGAGEPDFPTPDYIVEAAVEACRNPKYHRYTPAGGLPELKAAIAAKTLRDSGYEVEASQVLVTNGGKQAIYEAFAAILDPGDEVIVPAPYWTTYPESIRLAGGVPVDVVADETTGYRVSVEQLEAARTERTKVVLFVSPSNPTGSVYSEADAKAIGEWAAEHGLWVLTDEIYEHLVYGEAKFTSLPVLVPALRDKCIIVNGVAKTYAMTGWRVGWVIAPQDVIKAATNLQSHATSNVSNVAQVAALAAVSGNLDAVAEMRKAFDRRRQTMVKMLNEIDGVFCPTPEGAFYAYPSVKELLGKEIRGKRPQSSVELAALILDEVEVAVVPGEAFGTPGYLRLSYALGDEDLVEGVSRIQKLLAEAKA
What are the official names of this protein?
Aspartate aminotransferase, AspAT, Transaminase A.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRA_PSEPW
Sequence: MVLRSEILVNKNVMPTAEQALPGRETPMSLPEFHYVFKDTPLLGPFFEGSIDFAIFGLGCFWGAERRFWQREGVVSTVVGYAGGFTPNPTYEEVCSGLTGHTEVVLVVFDKDKVSYRELLAMFWELHNPTQGMRQGNDVGTQYRSAIYCTSPQQLEEAKASRDAFQAELNKAGYGEITTEIDQAPTVYFAEAYHQQYLAKNPDGYCGIGGTGVCLPPSLQGN
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: NFUA_VIBC1
Sequence: MSNITITETAQTHFANLLGQQPEGTNIRVFVVNPGTQNAECGVSYCPPEAVEGTDTEIPYSGFSAFIDELSLPFLEDAEIDFVTDKMGSQLTLKAPNAKMRKVSDDAPLVERVEYVIQTQVNPQLAGHGGHVNLVEITDDGIAIVAFGGGCNGCSMVDVTLKEGIEKELLNQFVGELTAVRDATEHDRGDHSYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: SKA1_HUMAN
Sequence: MASSDLEQLCSHVNEKIGNIKKTLSLRNCGQEPTLKTVLNKIGDEIIVINELLNKLELEIQYQEQTNNSLKELCESLEEDYKDIEHLKENVPSHLPQVTVTQSCVKGSDLDPEEPIKVEEPEPVKKPPKEQRSIKEMPFITCDEFNGVPSYMKSRLTYNQINDVIKEINKAVISKYKILHQPKKSMNSVTRNLYHRFIDEETKDTKGRYFIVEADIKEFTTLKADKKFHVLLNILRHCRRLSEVRGGGLTRYVIT
What is the function of this protein?
Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation (PubMed:17093495, PubMed:19289083, PubMed:23085020).  Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint (PubMed:17093495).  The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies (PubMed:19289083).  The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner (PubMed:19289083).  Affinity for microtubules is synergistically enhanced in the presence of the ndc-80 complex and may allow the ndc-80 complex to track depolymerizing microtubules (PubMed:23085020).  In the complex, it mediates the interaction with microtubules (PubMed:19289083, PubMed:23085020).
What are the official names of this protein?
Spindle and kinetochore-associated protein 1.
What is the protein family that this protein belongs to?
Belongs to the SKA1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Localizes to the outer kinetochore and spindle microtubules during mitosis in a NDC80 complex-dependent manner (PubMed:17093495). Localizes to both the mitotic spindle and kinetochore-associated proteins (PubMed:17093495). Associates with kinetochores following microtubule attachment from prometaphase, through mid-anaphase and then vanishes in telophase (PubMed:17093495).
Protein: MINE_ACIB3
Sequence: MAGFWSKLFSSEEKPSSAQTAKDRLKVIVASEQGLGRRLSQDKIDQMKKEIMQVVSRYVSGVGEQHIQMQVRSEANIEMLEMNINLPEER
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: COAD_ECO81
Sequence: MQKRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPSKKPMFTLEERVELAQQATAHLGNVEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEMQLAHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVHQALMAKLA
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CISY_CHICK
Sequence: ASSTNLKDVLAALIPKEQARIKTFRQQHGGTALGQITVDMSYGGMRGMKGLVYETSVLDPDEGIRFRGFSIPECQKLLPKGGXGGEPLPEGLFWLLVTGQIPTGAQVSWLSKEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAITALNSESNFARAYAEGILRTKYWEMVYESAMDLIAKLPCVAAKIYRNLYRAGSSIGAIDSKLDWSHNFTNMLGYTDAQFTELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLGWLAQLQKAXXXAGADASLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPGDPMFKLVAQLYKIVPNVLLEQGAAANPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTDGLIAL
What are the official names of this protein?
Citrate synthase, mitochondrial, Citrate (Si)-synthase.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: Y073_STRMU
Sequence: MDIKQVTETIAMIEEQNFDVRTITMGISLLDCIDSNIEKAAEKVYHKIVTKAGKLVQVGDDISAELGIPIVNKRVSVTPISIIGAATDATDYVPLAKALDRAAKEIGVNFIGGFSALVQKGYQKGDEILINSIPKALAETDFVCSSVNIGSTKSGINMTAVRDMGRIIKETSAASEMGPAKLVVFANAVEDNPFMAGAFHGVGEADVVINVGVSGPGVVKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGSLASERLGVKFGIVDLSLAPTPAVGDSVARVLEEMGLETIGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDEGMIAAVQEGALNLEKLEAMTAICSVGLDMIAIPANTPDTTIAAMIADEAAIGVINQKTTAVRIIPKGKEGDMIEFGGLLGYAPVMPVNKKSSADFIARGGQIPAPIHSFKN
What are the official names of this protein?
UPF0210 protein SMU_73.
What is the protein family that this protein belongs to?
Belongs to the UPF0210 family.
Protein: RPOC1_PELHO
Sequence: MIDKYQEPKHHQLRIGLVSPQQIMAWANKTLPTGEIVGEVKNYRTFSYDRDSETYKPERDGLFCERIFGPIKSGVCACGESRKIGDEKEKRTFCEKCGVEFVDSRIRRYQMGYIKLASPMAHVWYLKRIPSYIANLLDEKIKDLENLVYRDFIFAGPLTKKPTLLRLRGSFPESKTKFSGSRDILSQFLKTKSFQKLRDREFSAGAGAIRKRLANLDLEVIIYSSLAEWKKRKEQKAEIEIKPTRTERTEEEDRKIEKIKRRMRVLVRRMELAKHFLETNVKPEWMILRLLPVLPPELRPIFKISEVQFISSDLNTLYKEVISNNKILSDSLLGCKFVPEQLLTGQEKIVQVAVDQLLDNRISGQPRRDRNKQLYKSFSDILAGKEGRFRQTLLGRRVDYSGRSVIVVGPSLALHQCGLPREIALELFQTFIIRSLIRQRLASSVKTAKKQIREQERIVWDILEEVVQEHPVLLNRAPTLHRLGIQAFQPILTKERAIYLHPLVCKGFNADFDGDQMAVHLPLSLEAQAEAYLLMFSTQNLLSPGNGDPICVPTQDMLTGLYTLTLGNRRGICATRYNLWNRRNSQNERIDDKHYGSTKGKELLFCNPDDAIGAYRQKRINLDSPFWLKVTWGQHRIVSKELPVEVHYESLGTHHEIYGHCKIVRSVKTERHFIYIRTTVGHLFLDREIEDALKDFRARVV
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', PEP, Plastid-encoded RNA polymerase subunit beta', RNA polymerase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FABZ_BURP6
Sequence: MSTEKINFDIHKILTLLPHRYPILLVDRVLELEPHKAIKALKNVTVNEPFFTGHFPKRPVMPGVLIIEALAQAAALLTFAEAQPKDPENTLYYFVGIDNARFKRVVEPGDQLILNVTFERYIRGIWKFKAVAEVDGKVAAEAELMCTVKTADAAP
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_ACIC1
Sequence: MSSDPRDVLLAPVISEKSYGLLDQNKYTFLVPPESNKTQIKIAVEKVFNVRVLDVNTINRQGKRKRTRRGWGQRKNTKRAIVTVAPGDRIDIFGPPVS
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: HFQ_HERAR
Sequence: MTNKGQLLQDPFLNALRKEHVPVSIYLVNGIKLQGHIESFDQYVVLLRNTVTQMVYKHAISTVVPARAVNLSLESDAE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: HFLD_ECO81
Sequence: MAKNYYDITLALAGICQSARLVQQLAHQGHCDGDALHVSLNSIIDMNPSSTLAVFGGSEANLRVGLETLLGVLNASSRQGLNAELTRYTLSLMVLERKLSSAKGALDTLGNRINGLQRQLEHFDLQSETLMSAMAAIYVDVISPLGPRIQVTGSPAVLQSPQVQAKVRATLLAGIRAAVLWHQVGGGRLQLMFSRNRLTTQAKQILAHLTPEL
What is the function of this protein?
Negative regulator of phage lambda lysogenization.  Contributes to the degradation of the phage regulatory protein CII.  Acts probably by holding CII on the membrane surface, away from the target promoters, but close to the FtsH protease.
What are the official names of this protein?
High frequency lysogenization protein HflD.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y1791_XANOR
Sequence: MNLAPTTLLLFAATALAELVGCYLPYLWLRNGGSVWLLLPTALRLASFVWLLSLHPDASGRVYAAYGGVYIASALGLWLWWVDGVTPTRWDLLGAVCCLFGMAIIMFAPRSA
What are the official names of this protein?
UPF0060 membrane protein XOO1791.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NRBP_MACFA
Sequence: MSEGESQTVLSSGSDPKVESSSSAPGLTSVSPPVTSTTSAASPEEEEESEDESEILEESPCGRWQKRREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDNLIQLEHLNIVKFHKYWADIKENKARVIFITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGSVAPDTINNHVKTCREEQKNLHFFAPEYGEVTNVTTAVDIYSFGMCALEMAVLEIQGNGESSYVPQEAISSAIQLLEDPLQREFIQKCLQSEPARRPTARELLFHPALFEVPSLKLLAAHCIVGHQHMIPENALEEITKNMDTSAVLAEIPAGPGREPVQTLYSQSPALELDKFLEDVRNGIYPLTAFGLPRPQQPQQEEVTSPVVPPSVKTPTPEPAEVETRKVVLMQCNIESVEEGVKHHLTLLLKLEDKLNRHLSCDLMPNENIPELAAELVQLGFISEADQSRLTSLLEETLNKFNFARNSTLNSAAVTVSS
What is the function of this protein?
Required for embryonic development (By similarity).  Plays a role in intestinal epithelial cell fate and proliferation, thereby involved in the architectural development of the intestine potentially via the regulation of Wnt-responsive genes (By similarity).  May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases (By similarity).
What are the official names of this protein?
Nuclear receptor-binding protein.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.