PharMolix/UniProtQA huggingface dataset:
Protein: GCAL2_ARATH
Sequence: MATSLARISKRSITSAVSSNLIRRYFAAEAVAVATTETPKPKSQVTPSPDRVKWDYRGQRQIIPLGQWLPKVAVDAYVAPNVVLAGQVTVWDGSSVWNGAVLRGDLNKITVGFCSNVQERCVVHAAWSSPTGLPAQTLIDRYVTVGAYSLLRSCTIEPECIIGQHSILMEGSLVETRSILEAGSVLPPGRRIPSGELWGGNPARFIRTLTNEETLEIPKLAVAINHLSGDYFSEFLPYSTIYLEVEKFKKSLGIAI
What is the function of this protein?
Involved in complex I assembly in mitochondria and respiration.
What are the official names of this protein?
Gamma carbonic anhydrase-like 2, mitochondrial, AtCAL2, GAMMA CAL2.
What is the protein family that this protein belongs to?
Belongs to the gamma-class carbonic anhydrase family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Peripheral membrane protein; Matrix side. Note=Probably integral to the membrane.
Protein: ZG8_XENLA
Sequence: TGEKPFTCKECGKGFTQKRNLASHMTIHTGEKPFSCTECGKGFTQKRNLASHLTIHTGEKPFPCTECGKGFTQKSNLVSHMKIHTGEKPFTCTECGKEFAHKHRLLGHLKIHTGEKPFSCTECGKHFAHKYHLVSHMKIHTREKPFTCTECGEHFANKVSLLGHLKMHKGEKPFTCTECGNSFTQVSSLVSHMKIH
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Gastrula zinc finger protein XlCGF8.2DB.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CC103_MOUSE
Sequence: MEKNDVINFKALEKELQAALAADEKYKRENAAKLRAVEQRVPSYEEFRGIVLASHLKPLEQKDKMGGKRFVPWNCHTTRERTSQDVVTEIPQEKSPFQPTTSAEFYRDWRRHLRSGPERYQALLQLGGPKLGHLFQMDVGFGLLGELLVALAEHARLSDRTAVLGILHSLANTGRFNLNLSLLSHAERESCQRLFQKLQAMSTTRPMQEGLTVEEPSAGLQGEEGLLQELLELYGVH
What is the function of this protein?
Dynein-attachment factor required for cilia motility.
What are the official names of this protein?
Coiled-coil domain-containing protein 103.
What is the protein family that this protein belongs to?
Belongs to the CCDC103/PR46b family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, cilium, flagellum.
Protein: RL362_KOCRD
Sequence: MKVRTSLRSLKQIPGSQVVRRRGKTYVINKKNPRMKARQG
What are the official names of this protein?
50S ribosomal protein L36 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: DNAJ_BUCA5
Sequence: MAKKDYYQILGIPKSAEEREIKKAYKKLAMKYHPDRNQGDKTAEGKFKEIKEAYEILINEEKRSAYDQYGHAAFENGQSNSTYSTFTNSADFSDIFGDVFGDIFGGNRTQRAKKGADLCYNMEITLEEAVKGIKKEIQIPTLQKCKTCYGSGTRTGTKPRSCSTCHGKGQIHIRKGFFTVQQSCPTCHGKGTIITDPCNLCHGQGRVETYKILSVKIPPGLDTNDRIRLNNEGEAGANGAQSGDLYVQITVKKHPIFEREGNNLYCEVPINFTMAALGGEIEVPTLDGRVKLKIPYETQSGKLFRIRGRGVKSVQNRNQGDLLCRVVVETPVNLNEQQKNLLHELGNSFHGFRGEKNSPRSKRFFDGVKRFFDDLTR
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIMT_RALSO
Sequence: MSERSRGRRFPLTLDAVVERKPAERQREKRISSGVNAVSLPTPARTASAERASSTPAPGPGPQRVAGVDAAVGAVAASAVQARTQAAHAAAGGMASDRARQALVARVQAAGVTDARVLAAIGRVPRHLFVDAGLASQAYEDAALPIGHQQTISKPSVVGRMIELLLRERPEPSAQAAQVPAQPLSRVLEIGTGCGYQAAVLSQVAGEVYSIERIRPLHEKAKANLRPLRVPNIRLHYGDGMLGLPKAAPFDAIIVAAAGLEVPQALLDQLAIGGRLIAPVATDRAGGPSQQLVLIERRGRFQFHSTALEGVFFVPLKSGTV
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANFB_HUMAN
Sequence: MDPQTAPSRALLLLLFLHLAFLGGRSHPLGSPGSASDLETSGLQEQRNHLQGKLSELQVEQTSLEPLQESPRPTGVWKSREVATEGIRGHRKMVLYTLRAPRSPKMVQGSGCFGRKMDRISSSSGLGCKVLRRH
What is the function of this protein?
May have a role in cardio-renal homeostasis (PubMed:17372040).  Able to promote the production of cGMP (PubMed:17372040).
What are the official names of this protein?
Natriuretic peptides B, Brain natriuretic factor prohormone, preproBNP, proBNP, Gamma-brain natriuretic peptide, Iso-ANP.
What is the protein family that this protein belongs to?
Belongs to the natriuretic peptide family.
What are the subcellular locations of this protein?
[NT-proBNP]: Secreted. Note=Detected in blood. SUBCELLULAR LOCATION: [proBNP(3-108)]: Secreted. Note=Detected in blood. SUBCELLULAR LOCATION: [Brain natriuretic peptide 32]: Secreted. Note=Detected in blood. SUBCELLULAR LOCATION: [BNP(3-32)]: Secreted. Note=Detected in blood.
Protein: YHEU_SALHS
Sequence: MIIPWQGLAPDTLDNLIESFVLREGTDYGEHERSLEQKVADVKRQLQSGEAVLVWSELHETVNIMPKKQFRE
What are the official names of this protein?
UPF0270 protein YheU.
What is the protein family that this protein belongs to?
Belongs to the UPF0270 family.
Protein: FLIE_ECOSE
Sequence: MSAIQGIEGVISQLQATAMSARAQDSLPQPTISFAGQLHAALDRISDTQTAARTQAEKFTLGEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV
What are the official names of this protein?
Flagellar hook-basal body complex protein FliE.
What is the protein family that this protein belongs to?
Belongs to the FliE family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: METE_BACAN
Sequence: MAIQTSNLGYPRIGLQREWKKTLEAFWSNKINEEQFLTTMKEIRLQHVKVQQEKGIELIPIGDFTYYDHVLDTAYMLGFIPSRFSEFTSYLDVYFAMARGSKDHVASEMTKWFNTNYHYIVPEYEEGLQISLKDNRPLRLYEEAKQELGVDGKPVILGPYTFLKLAKGYTQEQFATILKQLVAPYVQLLSELHAAGAQIIQVDEPIFASLTKEEVQQAKEIYEAIRKEVPNATLLLQTYFDSVEENYEEIITFPVSSIGLDFVHGKEGNLNAISKYGFPADKTLAVGCIDGRNIWRADLDEVLTLFTTLQKQVQTKDLIVQPSCSLLHTPIDKTEETHLSTELFDALAFANQKLEELVLIHSALTQGTESISNELETYRNVHHTIRSSAARNREDVKAARTALKEEDFSRPLPFEKRYELQQVALKLPLLPTTTIGSFPQTTEVRQTRKEWRNGIISNEQYEQFIEKETEKWIRYQEEIGLDVLVHGEFERTDMVEYFGERLAGFSFTKNGWVQSYGSRCVKPPVIYGDVAFINGMTIKETVYAQSLTEKVVKGMLTGPVTILNWSFVRNDIPRKEVSYQIALALRHEIELLESSGIRVIQVDEPALREGMPLKEKDWDAYITWAVQSFLLATSSVANETQIHTHMCYSNFEDIVDAIRALDADVISIETSRSHGEFIDTLKHTTYEKGIGLGVYDIHSPRVPSKDEMYKIVEQSLQVCDPKYFWINPDCGLKTRRTEEVIPALEHMVQAAKDARSLLKTNA
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: NMD3_XENLA
Sequence: MEYMKGPATSSQGNILCCQCGIPIPPNPANMCVACLRTQVDISEGIPKQVSVHFCKQCERYLQPPGTWIQCALESRELLTLCLKKLKANLSKVRLIDAGFIWTEPHSKRLKVKLTIQKEVMNGAILQQVFVVDYVVQAQMCDDCHRVEAKDFWKAVVQVRQKVLHKKTFYYLEQTILKHRLHQNTLRVKEIHDGLDFYYASKQHGQKMVEFLQCTVPCRFKASQRLISHDIHTNAYNYKSTFSVEIVPVCKDNLVCLSPKLAQSLGNMNQICICARVTSTIHLIDPSTLQIAEVDGNTYWRYPFNSLFHPKQMEEFIVMDTEIIRDRKQAAGAGMRSNKHVLAEVWVQKTSEMNTTQQYHCRTHLGHLLNPGDLVLGFDLSNCNLNDEFINKMNPHHIPDVVLIKKSYDRARRQRRRNWKLKEMDRDREGMDTDDERQYQDFLEDLEEDELLRKNVNIFKNANVPVESDTDEEGAPRISLAEMLEDLHISQDATGEEGAGMLTE
What is the function of this protein?
Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
What are the official names of this protein?
60S ribosomal export protein NMD3.
What is the protein family that this protein belongs to?
Belongs to the NMD3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the nucleus/nucleolus and the cytoplasm in a XPO1/CRM1-dependent manner.
Protein: Y4290_CUPNH
Sequence: MQVLVDADACPVVVKEMLYRAAQRVEVCVTLVANQYMRTPPSRFIKSLQVPAGFDVADDRIVELVSSGDLVITADIVLAAAALDKGAYVLDPRGSWFSRENIQERLTMREVMEQLRSSGVDTGGPAAYAQQDSKAFAGQLDRFLARHAPPGAVA
What are the official names of this protein?
UPF0178 protein H16_B0290.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: OLNB2_BRANA
Sequence: QASIFSRFFRMFSFIFPFVNVIKLIIASVTSLVCLAFSCVALGGSAVALIVSTPLFIMFSPILVPATIATTLLASGLMAGTTLGLTGIGLIMGLVRTAGGVSLLQSPLRKIIVNRIKARLGGGGGGSRLARLKKILGLLNKLRGMGAGGAAAPAAEPAPAAEAAPAAEAAPAAAPAAAPAAAP
What is the function of this protein?
Many of the major pollen coat proteins are derived from endoproteolytic cleavage of oleosin-like proteins.
What are the official names of this protein?
Oleosin-B2, Oleosin-C98.
What is the protein family that this protein belongs to?
Belongs to the oleosin family.
What are the subcellular locations of this protein?
Lipid droplet. Membrane; Multi-pass membrane protein. Note=Surface of oil bodies. Oleosins exist at a monolayer lipid/water interface.
Protein: RUVA_YERPB
Sequence: MIGRLRGIILEKQPPLVLLETNGVGYEVQLPMTCFYELPELGQEAIIFTQFVVREDAQLLYGFNNKQERALFRELIKVNGVGPKLALAILSGMSAQQFVGAVEREDITTLVKLPGVGKKTAERLVVEMKDRFKGLNGDLFNNTGDISLPTASPQTSDADIEAEAASALVALGYKPQEASRLVSKIAKPGADCETLIRDALRAAL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: UVRC_BACC4
Sequence: MHEHLKEKLAILPDQPGCYLMKDKQGTVIYVGKAKVLKNRVRSYFTGSHDGKTLRLVGEIVDFEYIVTSSNLEALILELNLIKKYDPKYNIQLKDDKTYPFIKITAEKQPRLLITRNVKKDKGKYFGPYPNAQSAHETKKLLDRMYPLRKCTNMPDKVCLYYHMGQCLAPCVKEVTEEQNKEIVDEIIKFLNGGHKEVRSELEIKMYEASEKLEFERAKELRDQIAHIDAIMEKQKMIMSDLVDRDVFGYAVDKGWMCVQVFFVRKGKLIERDVSMFPIYDEPEEGFLTFIGQFYENSSHFKPKEIVVPGSIDSELVERFLEVEATQPKRGKKKDLVELANKNAKIALEEKFYLIERDEERTIKAVDHLGKQLGIETPYRIEAFDNSNIQGTNPVSAMIAFIDGKPAKKEYRKYKIKTVQGPDDYESMREVVRRRYTRALKENSPLPDLIIIDGGKGHLAAASDILENELGLYIPMAGLVKDDKHKTSHLIIGVPPEPVMLERNSQEFYLLQRIQDEVHRFAITFHRQLHGKSVIQSALDDIPGIGDKRKKVLLKHFGSLKKMKEASIEEFVEAGMPKNVAETIYTYLTDKKTL
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3MGH_RICPR
Sequence: MNKLIPLPREFFARDTNLVSTELIGKVLYFQGTTAIITETESYIGEDDPACHAARGRTKRTDVMFGPAGFSYVYLIYGMYYCLNFVTEDEGFPAATLIRGVYVISHNNVYTIDTAKIKSQITDEKTQSIIIRKNRRIMKFYIPNLKASNLYLNGPGKLCKYLGINTSYNKCDLINNKDFFVSDIGLNLPYYSTTRIGITKGTDKLWRYIVTDPKMLY
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: GPA2_SCHPO
Sequence: MTIFNGLSESGESKKLNSKIEKQIENASKKDKKIYKVLLLGASDSGKSTISKQIKILNKNGFSQEEIMTFIPVIRRNLLESAKTLVKIIVQKGINLDPLGTHNCEIIEKFNPTPGELINANIGQAITSLWSANSVRSCTYGNDSVLIDSAPYFFSRADEICSRHYVPTIDDILRSRNSTLGISEISFTLDHLQIRMFDVGGQRTERRKWIYCFENVNSIIFCVSLNDYDKKLYERAAPERNRLVESISLFDSIINSQWFMHSSIILFLNKFDLFRKKLEHVPFQDYFPQYEGKNSVKSITRYILWLFVNPSINRAKHNIYPHITTAVDTSNIKVVFSAVKETILQHSLKEAGMF
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.  This protein may be involved in the determination of the cAMP level according to nutritional conditions, most probably as a regulator of adenylyl cyclase.
What are the official names of this protein?
Guanine nucleotide-binding protein alpha-2 subunit, GP2-alpha.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family.
Protein: CSG_METAC
Sequence: MKRFAALSLAALMLLTVFASAASAVDVIEIRGPVYNGSDIDDIIDTYGDGTILTMDATDFAAFYYDIDDNVTTETLSIEDVPDTEGNVIGEGGLIYETTIQEVEYEYYNPDAGWDNYSLMGFFAEKYIPINPDKADKLSKLILDSDDKYTIRTGEMLDLGEGYAIEAKQVDVDGEKVWLEFTKDGEFVDDEIISVSTADDEANTWDVELDDIEDEDDVIVLKVHVNQVFQGAVDSIAQIEGLWLIDYANAMTIESDDEFGNLDDVSIDGDTLTITNEDTFTLTRDDEEEIGEGLYFATADTPSNVLRFYAMKEITDPGTYEIRGQVASGFGDQSWDASSFAGFYYDIDDNVSTETLTVSDLDGNVIPEGGLVYTTTIADVDFEYYNPDAGWDQYPVMGFFAEEYIPINPDKADKIAKLVLDSDDKYTIRTGEMLDLGEGYAIEAKQVDVDGEKVWLEFTKDGEFVDDEIISVSTADDEANTWDVELDDIEDEDDVVVLKVHVNQVFQGAVDSIAQIEGLWLIDYANAMTIESDDEFGNLDDVSIDGDTLKISNEDTFTLTRDSEEEIGEGMYFMIADTSSSDLRYYPYVEKTIGEEVSGEEETPEETPTGEVTETEGEEETPTEVTETPTEGEPAPEETETTESEGTTPGFGFMFGLVGLLAVVYLVRRNN
What is the function of this protein?
S-layer protein.  The S-layer is a paracrystalline mono-layered assembly of proteins which coat the surface of the cell.
What are the official names of this protein?
Major S-layer protein, Cell surface glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the Methanosarcinales S-layer protein family.
What are the subcellular locations of this protein?
Secreted, cell wall, S-layer. Cell membrane.
Protein: DDL_PSEPF
Sequence: MTAAYANLFSTIAPKDFGRVAVLFGGLSAEREVSLKSGNAVLTALQSAGVDAFGIDVGADILQRLLSEKIDRAFIILHGRGGEDGSMQGLLEVAGIPYTGSGILASALAMDKLRTKQVWHTLGIPTPRHAVLRSEADCISAATELGFPLIVKPAHEGSSIGMAKVSSASELIDAWKAASTYDSQVLVEQWIHGPEFTIATLRDQVLPPIALGTPHTFYDYDAKYIANDTQYRIPCGLDAAKEKELMDLTAQACEALGIAGWGRADVMQDADGKFWFLEVNTAPGMTDHSLVPMAAKAAGLDFQQLVLAILAASVDADGKKEARG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBZ_ORYSI
Sequence: MTIAFQLAVFALIVTSSVLVISVPLVFASPDGWSNNKNVVFSGTSLWIGLVFLVAILNSLIS
What is the function of this protein?
Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna.
What are the official names of this protein?
Photosystem II reaction center protein Z, PSII-Z.
What is the protein family that this protein belongs to?
Belongs to the PsbZ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein. Note=Associated with the photosystem II complex.
Protein: PUR7_MACCJ
Sequence: MTLVYEGKAKRVYSTDEDHVFRIEYKDEVTAGNGAKKDNMAGKGRLNNLITSYFFERLARQGLESHFIKKLSDTEQLVKAVTIIPLEVVVRNYAAGSIVKRLGFDKGVQFKSPLVEFYYKEDALNDPIITDDHVKLLGIADDDDIAELKRQALIINDMLVKMMDEMNLQLIDFKIEFGKDQDGNILLADEISPDTCRIWDKDTKENFDKDVYREDTGSLIDTYTQFYNKLEAL
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: SP2SA_BACAN
Sequence: MSLVISNIRIGLFILAIVFLVLVFFYWRNEELYEEKKQRIRKTWYGLFIVSVTVYFMIKGIDLTLWKNLLMFTAMVIFVDIAFILTPNISEIWGAKFSDIGKTVQSIKRSLIASKARGEIYTTIIQNVNPAVFGTMEWHTEEEYTKSLNAFLDSYGEKIGAKIVVFEAAKELNTNFRGIRSQFSTIIPLEYIEQLNEQRAVQVENVGIIPAKIVSDVFIVIDGKKNNLQDRDFENVYNLTIHHSYFSK
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  Upon expression in E. coli growth ceases.
What are the official names of this protein?
Stage II sporulation protein SA, Killer protein SpoIISA, Toxin SpoIISA.
What is the protein family that this protein belongs to?
Belongs to the SpoIISA toxin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MCEL_MONPV
Sequence: MDANIVSSSTIATYIDALAKNASELEQRSTAYEINNELELVFIKPPLITLTNVVNISTIQESFIRFTVTNKEGIKIRTKIPLSKVHGLDVKNVQLVDAIDNIVWEKKSLVTENRLHKECLLRLSTEERHIFLDYKKYGSSIRLELVNLIQAKTKNFTIDFKLKYFLGSGAQSKSSLLHAINHPKSRPNTSLEIEFTPRDNETVPYDELIKELTTLSRHIFMASPENVILSPPINAPIKTFMLPKQDIVGLDLENLYAVTKTDGIPITIRVTSKGLYCYFTHLGYIIRYPVKRTIDSEVVVFGEAVKDKNWTVYLIKLIEPVNAISDRLEESKYVESKLVDICDRIVFKSKKYEGPFTTTSEVVDMLSTYLPKQPEGVILFYSKGPKSNIDFKIKKENTIDQTANVVFRYMSSEPIIFGESSIFIEYKKFTNDKGFPKEYGSGKIVLYNGVNYLNNIYCLEYINTHNEVGIKSVVVPIKFIAEFLVNGEILKPRIDKTMKYINSEDYYGNQHNIIVEHLRDQSIKIGDVFNEDKLSDVGHQYAANNDKFRLNPEVSYFTNKRTRGPLGILSNYVKTLLISMYCSKTFLDDSNKRKVLAIDFGNGADLEKYFYGEIALLVATDPDADAIARGNERYNKLNSGIKTKYYKFDYIQETIRSDTFVSSVREVFYFGKFNIIDWQFAIHYSFHPRHYATVMNNLSELTASGGKVLITTMDGDKLSKLTDKKTFIIHKNLPSSENYMSVEKIADDRIVVYNPSTMSTPMTEYIIKKNDIVRVFNEYGFVLVDNVDFATIIERSKKFINGASTMEDRPSTRNFFELNRGAIKCEGLDVEDLLSYYVVYVFSKR
What is the function of this protein?
Catalytic subunit of the mRNA capping enzyme which catalyzes three enzymatic reactions: the 5' triphosphate end of the pre-mRNA is hydrolyzed to a diphosphate by RNA 5' triphosphatase; the diphosphate RNA end is capped with GMP by RNA guanylyltransferase and the GpppN cap is methylated by RNA (guanine-N7) methyltransferase.  Heterodimeric mRNA capping enzyme catalyzes the linkage of a N7-methyl-guanosine moiety to the first transcribed nucleotide (cap 0 structure), whereas the methyltransferase OPG102 is responsible for a second methylation at the 2'-O position of the ribose (cap 1 structure).  Also involved in early viral gene transcription termination and intermediate viral gene transcription initiation.  Early gene transcription termination requires the termination factor VTF, the DNA-dependent ATPase NPH-I/OPG123 and the RAP94/OPG109 subunit of the viral RNA polymerase, as well as the presence of a specific termination motif.  Binds, together with RAP94/OPG109, to the termination motif 5'-UUUUUNU-3' in the nascent early mRNA.
What are the official names of this protein?
mRNA-capping enzyme catalytic subunit, Virus termination factor large subunit, VTF large subunit, mRNA-capping enzyme 97 kDa subunit, mRNA-capping enzyme D1 subunit, mRNA-capping enzyme large subunit.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
Protein: DXS_RHOPA
Sequence: MTEFSKTPLLDTIRTPEDLRKLRIDQVRQVADELRLETIDAVSVTGGHFGAGLGVVELTTALHYVFDTPRDRLIWDVGHQAYPHKILTGRRDRIRTLRTGGGLSGFTKRTESDHDPFGAGHSSTSISAGLGMAVASELAGKKNNVIAVIGDGSISAGMAYEAMNNAGAMNSRLIVILNDNNMSIAPPVGAMSAYLSRLYSGKTYRSLREAGKQIGKHLPKLIADRAARAEEYSRGFMMGGGTLFEELGFYYVGPVDGHNLDHLLPILQNVRDADTGPFLIHVVTQKGKGYGPAEAAADKYHAVVKFDIATGAQAKAKSNAPSYQNVFGQSLVKEAQKDDKIVGITAAMPSGTGIDIFEKAFPKRTFDVGIAEQHAVTFAAGLATEGYKPFCAIYSTFLQRAYDQIVHDVAIQKLPVRFAIDRAGLVGADGATHAGSFDNAYLGCLPNMVIMAAADEAELVHMVATQVAIDDRPSAVRYPRGEGRGVEMPEVGIPLEIGKGRVIRQGNKVALLSFGTRLAEAEKAADELATLGLSTTVADARFMKPLDVELVLKLARDHEVLLTIEEGSIGGFGSHVMQTLAEHGMLDGEVKMRALVLPDVFMDHDNPVAMYARAGLDAKAIVKKVFDVLGKDAATETSKLA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: BAS2_MAGO7
Sequence: MVRVSTFAAILAMALSVTANVTPNDAGAKNVGTGNGQQFITGGCVNGTDCQSRCCAGNGENKGVCSNEVAANQNGKTGCGFEDPNKAQTVKEAKEQVKKQGF
What is the function of this protein?
Secreted effector involved in biotrophic colonization of plant cells.
What are the official names of this protein?
Biotrophy-associated secreted protein 2.
What are the subcellular locations of this protein?
Secreted. Note=Secreted into the biotrophic interfacial complexes (BICs).
Protein: END8_SALPA
Sequence: MPEGPEIRRAADNLEAAIKGKPLTDVWFAFAQLKPYESQLTGQIITRIETRGKALLTHFSNGLTLYSHNQLYGVWRVIDTGEIPQTTRILRVRLQTADKTILLYSASDIEMLTAEQLTTHPFLQRVGPDVLDARLTPEEVKARLLSPRFRNRQFSGLLLDQAFLAGLGNYLRVEILWQVGLTGQHKAKDLNEAQLNALSHALLDIPRLSYTTRGQADENKHHGALFRFKVFHRDGEACERCGGIIEKTTLSSRPFYWCPHCQK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine.  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Endonuclease 8, DNA glycosylase/AP lyase Nei, DNA-(apurinic or apyrimidinic site) lyase Nei, Endonuclease VIII.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: DAPH_BACAN
Sequence: MKMMDANEIISFIQKSEKKTPVKVYIKGDLKEVTFPETVQAFVNKKSGVLFGEWSEIKTILDENSKYIVDYVVENDRRNSAIPMLDLKGIKARIEPGAIIRDHVEIGDNAVIMMNATINIGAVIGEGSMIDMNAVLGGRATVGKNCHVGAGAVLAGVIEPPSAKPVIVEDDVVIGANVVVLEGVTVGKGAVVAAGAVVTEDVPPYTVVAGTPARVIKEIDEKTKAKTEIKQELRQLNPEK
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. DapH subfamily.
Protein: VE4_HPV13
Sequence: MAEDTVLYKKYPLLGLLHTPPPPPHRPPPQCPAAPRKNVCKRRLVNDNEDLHVPLETPRTHKALCVSQTTTPWTVQTTTSTLTITTITKDGTTVTVQLHL
What is the function of this protein?
Contributes to multiple aspects of the viral life cycle including viral genome amplification, suppression of suprabasal cell differentiation and egress of newly formed virions.  Induces host cell cycle arrest at the G2 phase by associating with and preventing the nuclear entry of host CDK1/cyclin B1 complexes.  Inhibits cellular DNA replication by preventing loading of host replication licensing proteins MCM2 and MCM7 onto chromatin.  Within the cytoplasm, associates with host kinase SRPK1, a splicing factor regulator, and inhibits its activity.  Therefore, E4 favors expression of late viral transcripts by inhibiting SRPK1-mediated phosphorylation of host serine-arginine (SR) proteins that have critical roles in mRNA metabolism.  Late in the infectious cycle, E4 also acts to diminish the integrity of the keratinocyte by disrupting the keratin cytoskeleton and inducing apoptosis through alteration of mitochondrial function to facilitate egress of the newly formed virions.
What are the official names of this protein?
Protein E4.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E4 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.