PharMolix/UniProtQA huggingface dataset:
Protein: DDL_LACAC
Sequence: MTKKIQVGLIFGGNSSEYEVSIVSGHNIYKAIDKDKFDVHPIWITNEGYFASEEESFKVLEDPSYQVENPHKVNNISNIIELKNLPEIDVFFPIVHGNLGEDGVLQGLFRLMNKPFVGDDVLAAAATMDKEFTKILAQRVGVPVADWISIKRFEYDDKNNDKLNYEKVAEKLGHDMFVKPSNQGSSVGVNHVTNAEEYAAALEEAFKYDDKVLVEETVPGTEVETAVLGNDKPIVAGVGQITNAKGSFYTYENKYDDNSTSKLQIPADLPQDIVDTVRENARKVYEITECSGMARIDSMLTPDGKVVLTEVNALPGFTNISMYPKLFEEAGIPYTELITRLIQAGMDRFDHKKTLLHKHD
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAD1_ARATH
Sequence: MVKSTSKDAQDLFRSLRSAYSATPTNLKIIDLYVVFAVFTALIQVVYMALVGSFPFNSFLSGVLSCIGTAVLAVCLRIQVNKENKEFKDLAPERAFADFVLCNLVLHLVIINFLG
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1, Oligosaccharyl transferase subunit DAD1, Defender against cell death 1, AtDAD1, DAD-1.
What is the protein family that this protein belongs to?
Belongs to the DAD/OST2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RF3_VIBA3
Sequence: MSFQQEVSKRRTFAIISHPDAGKTTITEKVLLFGNAIQKAGTVKGRGSNQHAKSDWMEMEKERGISVTTSVMQFPYNDCLVNLLDTPGHEDFSEDTYRTLTAVDSCLMVIDAAKGVEDRTRKLMEVTRLRDTPIVTFMNKLDRDVRDPMEVLDEVESELGMACAPISWPIGCGKEFKGVYHIHRDETILYESGHGHEIQEVRIIKGLDNPELDEAVGEDLASSVREELELVIGACPEFDHELFLAGELTPVYFGTALGNFGVDHMLDGLTRWAPAPQTRQANERDVEATEEKFSGFVFKIQANMDPKHRDRIAFMRIVSGTYDQGMKMNHVRTGKNVSISDAVTFMAGDRARAEKAYAGDIIGLHNHGTIQIGDTFTQGESLKFAGIPNFAPELFRRIRLRDPLKQKQLLKGLVQLSEEGAVQVFRPLQNNDLIVGAVGVLQFDVVVARLKAEYNVEAIYEGVNVATARWVECDDAKKLEEFKRKSQANLALDGGDNLSYIAPTMVNLNLASERFPEVQFRATREH
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGC_CLOK5
Sequence: MDRKEMISMILAGGQGSRLGILTKKLAKPAVPFGGKYRIIDFVLSNCSNSGIYTVGVLTQYKPLELNSHIGIGTPWDLDRRDGGVYVLPPYQEESGGNWYKGTADAIYQNISFVDNYNPEYVIILSGDHIYKMNYANMLKFHKEKKADVTIAVIEVPIEETYRFGIVNTKSDMEIYEFQEKPMKAKSTKASMGVYIFKWTLLKRFLKADQSDKNSSNDFGKNIIPNMLNSGIKMYAYPFRGYWKDVGTIQSLWEANMDLLKEDNELNLGDLNWRIYSVNHVEPAQYIGPKANIKSSIAVNGCEIYGEVKNSIISSGSIIGKNSKIIDSVIMPYSKIGDNVIINKALVGSNVVVRKNSIIGDGREITVIGSNKDIKAESLLVSS
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: ADPP_SHIFL
Sequence: MLKPDNLPVTFGKNDVEIIARETLYRGFFSLDLYRFRHRLFNGQMSHEVRREIFERGHAAVLLPFDPVRDEVVLIEQIRIAAYDTSETPWLLEMVAGMIEEGESVEDVARREAIEEAGLIVKRTKPVLSFLASPGGTSERSSIMVGEVDATTASGIHGLADENEDIRVHVVSREQAYQWVEEGKIDNAASVIALQWLQLHHQALKNEWA
What is the function of this protein?
Acts on ADP-mannose and ADP-glucose as well as ADP-ribose.  Prevents glycogen biosynthesis.  The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process (By similarity).
What are the official names of this protein?
ADP-ribose pyrophosphatase, ADP-ribose diphosphatase, ADP-ribose phosphohydrolase, ASPPase, Adenosine diphosphoribose pyrophosphatase, ADPR-PPase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudF subfamily.
Protein: Y108_SYNY3
Sequence: MSNSILSKLNVGERSPVNRTHSSRTEAEKSSLFRFVRRKINSPWLACVPLTALIVAIWNAAAIAQDTEIVNITVETVNENVATLQGTLNAIWILIAAILVIFMNAGFGMLETGLCRQKNAVNILTKNLIVFALATIAYWAIGFSLMFGSSGNPFVGFGGFFLSGDHTNYGLSPFPEGLPVAVFFLFQVAFSATAATIVSGAVAERIKFNEFLIFSVLLVGIAYPITGHWVWDAGGWLYTMGFMDFAGSTVVHSVGGWAALAGAFLLGPRLGKFVDGRPGAIPGHNMGFAMLGCLILWIGWFGFNPGSQLAADQACAYIAVTTNLAASAGGLTATFTSWLKDGKPDLTMVINGVLAGLVGITAGCAGVSYWGSVIIGGIAGILVVYSVAFFDKIKIDDPVGAISVHLVNGVWGTLAVGFFNMEKGLFYGGGINQLIIQIVGILAIGAFTAIFSFVVWAILKQTMGIRVSGEEEMIGLDIGEHGMEAYTGFVKETDSFGSAVSGATVPE
What are the official names of this protein?
Putative ammonium transporter sll0108.
What is the protein family that this protein belongs to?
Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RIMS1_RAT
Sequence: MSSAVGPRGPRPPTVPPPMQELPDLSHLTEEERNIIMAVMDRQKEEEEKEEAMLKCVVRDMAKPAACKTPRNAESQPHQPPLNIFRCVCVPRKPSSEEGGPERDWRLHQQFESYKEQVRKIGEEARRYQGEHKDDAPTCGICHKTKFADGCGHLCSYCRTKFCARCGGRVSLRSNNEDKVVMWVCNLCRKQQEILTKSGAWFFGSGPQQPSQDGTLSDTATGAGSEVPREKKARLQERSRSQTPLSTAAVSSQDTATPGAPLHRNKGAEPSQQALGPEQKQASRSRSEPPRERKKAPGLSEQNGKGGQKSERKRVPKSVVQPGEGIADERERKERRETRRLEKGRSQDYSDRPEKRDNGRVAEDQKQRKEEEYQTRYRSDPNLARYPVKAPPEEQQMRMHARVSRARHERRHSDVALPHTEAAAAAPAEATAGKRAPATARVSPPESPRARAAAAQPPTEHGPPPPRPAPGPAEPPEPRVPEPLRKQGRLDPGSAVLLRKAKREKAESMLRNDSLSSDQSESVRPSPPKPHRPKRGGKRRQMSVSSSEEEGVSTPEYTSCEDVELESESVSEKGDLDYYWLDPATWHSRETSPISSHPVTWQPSKEGDRLIGRVILNKRTTMPKESGALLGLKVVGGKMTDLGRLGAFITKVKKGSLADVVGHLRAGDEVLEWNGKPLPGATNEEVYNIILESKSEPQVEIIVSRPIGDIPRIPESSHPPLESSSSSFESQKMERPSISVISPTSPGALKDAPQVLPGQLSVKLWYDKVGHQLIVNVLQATDLPPRVDGRPRNPYVKMYFLPDRSDKSKRRTKTVKKLLEPKWNQTFVYSHVHRRDFRERMLEITVWDQPRVQDEESEFLGEILIELETALLDDEPHWYKLQTHDESSLPLPQPSPFMPRRHIHGESSSKKLQRSQRISDSDISDYEVDDGIGVVPPVGYRASARESKATTLTVPEQQRTTHHRSRSVSPHRGDDQGRPRSRLPNVPLQRSLDEIHPTRRSRSPTRHHDASRSPADHRSRHVESQYSSEPDSELLMLPRAKRGRSAESLHMTSELQPSLDRARSASTNCLRPDTSLHSPERERHSRKSERCSIQKQSRKGTASDADRVLPPCLSRRGYATPRATDQPVVRGKYPTRSRSSEHSSVRTLCSMHHLAPGGSAPPSPLLLTRTHRQGSPTQSPPADTSFGSRRGRQLPQVPVRSGSIEQASLVVEERTRQMKVKVHRFKQTTGSGSSQELDHEQYSKYNIHKDQYRSCDNASAKSSDSDVSDVSAISRASSTSRLSSTSFMSEQSERPRGRISSFTPKMQGRRMGTSGRAIIKSTSVSGEIYTLERNDGSQSDTAVGTVGAGGKKRRSSLSAKVVAIVSRRSRSTSQLSQTESGHKKLKSTIQRSTETGMAAEMRKMVRQPSRESTDGSINSYSSEGNLIFPGVRVGPDSQFSDFLDGLGPAQLVGRQTLATPAMGDIQIGMEDKKGQLEVEVIRARSLTQKPGSKSTPAPYVKVYLLENGACIAKKKTRIARKTLDPLYQQSLVFDESPQGKVLQVIVWGDYGRMDHKCFMGVAQILLEELDLSSMVIGWYKLFPPSSLVDPTLAPLTRRASQSSLESSSGPPCIRS
What is the function of this protein?
Rab effector involved in exocytosis.  May act as scaffold protein that regulates neurotransmitter release at the active zone.  Essential for maintaining normal probability of neurotransmitter release and for regulating release during short-term synaptic plasticity.  Plays a role in dendrite formation by melanocytes.
What are the official names of this protein?
Regulating synaptic membrane exocytosis protein 1, Rab-3-interacting molecule 1, RIM 1.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Synapse. Presynaptic cell membrane; Peripheral membrane protein. Note=Associated with plasma membranes from synaptic junctions. Not detected in synaptic vesicles. Detected in presynaptic nerve terminals close to the active zone. Detected in synaptic ribbons of ribbon synapses of retinal photoreceptor cells.
Protein: ZN790_HUMAN
Sequence: MAHLMMFRDVAVDFSQEEWECLDLEQRDLYRDVMLENYSNMVSLGFCIYQPEAFSLLEKGKEPWKILRDETRGPCPDMQSRCQTKKLLPKNGIFEREIAQLEIMRICKNHSLDCLCFRGDWEGNTQFQTLQDNQEECFKQVIRTCEKRPTFNQHTVFNLHQRLNTGDKLNEFKELGKAFISGSDHTQHQLIHTSEKFCGDKECGNTFLPDSEVIQYQTVHTVKKTYECKECGKSFSLRSSLTGHKRIHTGEKPFKCKDCGKAFRFHSQLSVHKRIHTGEKSYECKECGKAFSCGSDLTRHQRIHTGEKPYECNECRKAFSQRSHLIKHQRIHTGEKPYECKECGKAFTRGSHLTQHQRIHTGEKSHECKECGKAFIRGSNLAQHQNVHVGRKPYKCEKCGKAYIWSSHLARHQRIHTGRKPYECKQCGKTFTWASYLAQHEKIHNERKSYECKECGKTFLHGSEFNRHQKIHTGERNYECKECGKTFFRGSELNRHQKIHTGKRPYECEECGKAFLWGSQLTRHQRMHTGEEPYVCKECGKSFIWGSQLTRHKKIHTDAEPYGCKKSSHIFSHHSYFTEQKIHNSANLCEWTDYGNTFSHESNFAQHQNIYTFEKSYEFKDFEKAFSSSSHFISLL
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 790.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARGD_NEIMB
Sequence: MQNYLTPNFAFAPMIPERASGSRVWDTKGREYIDFSGGIAVNALGHCHPALVDALNAQMHKLWHISNIYTTRPAQELAQKLVANSFADKVFFCNSGSEANEAALKLARKYARDRFGGGKSEIVACINSFHGRTLFTVSVGGQPKYSKDYAPLPQGITHVPFNDIAALEAAVGEQTCAVIIEPIQGESGILPATAEYLQTARRLCDRHNALLILDEVQTGMGHTGRLFAYEHYGIVPDILSSAKALGCGFPIGAMLATEKIAAAFQPGTHGSTFGGNPMACAVGSRAFDIINTPETLNHVREQGQKLQTALLDLCRKTGLFSQVRGMGLLLGCVLDEAYRGRASEITAAALKHGVMILVAGADVLRFAPSLLLNDEDMAEGLRRLEHALTEFAATSDNP
What are the official names of this protein?
Acetylornithine aminotransferase, ACOAT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPP_BRUSU
Sequence: MDFFNLLEAAFLGLIEGLTEFIPVSSTGHLLLIGHFLGFESTGKTFEVLIQLGAILAILSVYSAKLARIATDFPRDARTRRFVLGVLVAFLPAAVIGALAHGFIKGVLFETPMLVCIMLIVGGFILLWVDQLNLRPRYHNVMDYPLPICLAIGFIQCLAMIPGVSRSGSTIVGSLLLGADKRSAAEFSFFLAMPTMAGAFAYDLFKSRNILSFNDGALIVVGFIMAFISGVFVVRHLLDYVSRHGFALFGWWRLIVGSAGMAALIIWG
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYB_BRAPC
Sequence: MSFRKTHPLIKIVNSTLVDLPSPANLSVNWNYGSLLGLVLVIQLITGIVLATRFSGHSDMSFDSVISIYQDSNYGWLLRLVHSTGASFFFLFIYLHIGRGLYYGSYVYPEVWNIGVLIYLILMGTAFLGYVLPWGQMSYWAATVITNLLSAIPWLGPTMVEWVWGGFAVGNPTLTRFFALHYLLPFVVTALVILHIFYLHIYGSSNPLGISSNTNKVSFHYYYSVKDLYVYFVFFFVFMVFTLKYGYVFMDAENFIPANPLVTPTHIQPEWYFLFAYAILRSIPNKLGGVVGLLLAVLVLFLFSVSTSKLLFSGTIYSPLARLLYWSLVSNFFLLTWLGSCPAESPYNEVALVATVTYFTFMLTMCALPHISTYLYLKS
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: V040_FOWPN
Sequence: MDIIKIQLDVAIKIYNYIKSTGTENIIIAPCSIISSLCALSKLTDHSTADKIYDILNIECQNIDLYMKKINDNMNSSDIDYFCKLGLNNVCINQRTKNILYNCYKTCTVDETEGCSIKFKNVLEFEALWNRPFTAPTEEQIRKRHNSVEIVSILVDAKRRLHMLRRLDNIGCSVVRTSLASNRYILTTISPNEDKEEIFNLLENSINVDSLLDWIDNSKMKKAQHRLKIPKIKMSSSYDIVELLKSLGLNLMEIKFSNVFPETTLFVERIAQSSIMEIKAESISLNTDIELEFTNNEYPKINCSSCSETVVGKPFIFILQCRVTGNCIYFGVLRDSF
What are the official names of this protein?
Uncharacterized serpin-like protein FPV040.
What is the protein family that this protein belongs to?
Belongs to the serpin family. Poxviruses subfamily.
Protein: ANG4_MOUSE
Sequence: MTMSPCPLLLVFVLGLVVIPPTLAQNERYEKFLRQHYDAKPNGRDDRYCESMMKERKLTSPCKDVNTFIHGTKKNIRAICGKKGSPYGENFRISNSPFQITTCTHSGASPRPPCGYRAFKDFRYIVIACEDGWPVHFDESFISP
What is the function of this protein?
Has bactericidal activity against E. faecalis and L. monocytogenes, but not against L. innocua and E. coli.  Promotes angiogenesis (in vitro).  Has low ribonuclease activity (in vitro).  Promotes proliferation of melanoma cells, but not of endothelial cells or fibroblasts (in vitro).
What are the official names of this protein?
Angiogenin-4.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle lumen. Secreted. Nucleus, nucleolus. Note=Exposure to bacterial lipopolysaccharide (LPS) triggers secretion from intestinal epithelium cells (PubMed:12548285). Rapidly endocytosed by target cells and translocated to the nucleus where it accumulates in the nucleolus and binds to DNA (By similarity).
Protein: THBG_BOVIN
Sequence: MPLFSLVLLILGLHCAPPNSCEGKITSCLSPQQNATLYKMSSINADFAFNLYRRFTVEIPDQNIFFSPVSIPAGLAMLSLGACSSTQTQILEGLGFNLTDTPVAEIQQGFQHLICSLNFPKKELELQMGNALFIGKQLKPLEKFLDDVKNLYETEVFSTDFSNVSAAQQEINSHVEKQTKGKIVGLIQDLKPNTITVLVNYLCFKAQWANPFDPSKTEEGSSFLVDKTTTVQVPMMHQMEQYYHLVDTELNCTVLQMDYSKNALALFVLPKEGQMEWVEGAMSSKTLKKWNRLLRKGWVDLFVPKFSISATYDLGDILLKMGIQDAFADNADFSGLTKDNGLKVSNVAHKAMFYIGEKGTEAVPEVRFLNQPETTLLHPIIQFDRSFLLLILEKNTRSILFLGKVVDPTEA
What is the function of this protein?
Major thyroid hormone transport protein in serum.
What are the official names of this protein?
Thyroxine-binding globulin, Serpin A7, T4-binding globulin.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RLMKL_SHEWM
Sequence: MLNFFAAAPRGYEYALSLELADLGASDIKESVAGVYFSASLELGYRITLWSRIASRIIFVIHKGPCESPEQLYNAAYGIDWQMEFNHRSTFSIDFHGMGGFINNTMFGALKIKDAIVDRFRDDDCPRPDVARVDADFRIDAHYRRGQITIGLNFSGPALHKRGYRDITGEAPLKENLAANMLMRSGWQKNPVSLLDPFCGSGTILIEAAMMACDMAPGLHRERFGFEHWLRHNDKYWQELLDEAKARASIGITRCKTKFYGSDIDSRIVALAKKNAANAGVLELIDFSVTNALNVKVPEETGYLITNPPYGERLGTVTALLQLYYQLGDKFKAEFGGWNLAVLNSDVELLSALKLKADKQMKMNNGALECAFNLYTVHATNTRRVDPSNINREGDVSDIAVPFVNRVKKNIKQLQKWAKKEGIDSYRIYDADLPDYKVAIDKYLDYVVIQEYTAPVDIPESVTKRRLTDVLITLPGAIGIDPNNIILKTREKQKGTNQYEKIQANKLELITTEYGAKFKLNLKEYLDTGLFLDHRLTRKLVGEKSKDRDVLNLFAYTGTASVHAALGGAKSVKTVDMSNTYTNWAKENFALNGLNDDKYQFVQANCMQWIKTTHDKFDLIFIDPPTFSNSKRMEDSFDVLRDHVPLLSSLIKLLNPNGEIIFSNNKRKFKMEIEALEALNFTVKNIDNQTLPLDFKRNPQIHNTWLLTHGG
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYSY_ONYPE
Sequence: MNTYLDLCRFILQKGSFRNDRTNTGTKSVFGYQMRFNLEEGFPLLTTKKMNLRSIIHELLWFLKGDTNICYLVQNNVNIWNEWPYQKYQQSAFFQNETLKEFLEKIKNDPLFAIKHGNLGPVYGKQWRDFNGVDQIKFLISEIKTNPNSRRLILNSWNPPLLNQMALPPCHVLIQFYVHQGKLSLQLYQRSGDVFLGIPFNIASYSLLLMMVAQVTNLQPYEFIHTLGDAHIYSNHLAQVQTQIQRTPKKLPQMILNPDIKNIDDFKFSDFTLQNYQCDGILKGDIAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTLD_STAAW
Sequence: MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDSSIEAGLRRVLAETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: EFTU_STRPJ
Sequence: MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSVNQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDLLSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPVEDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAGDNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQFYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGMVTEIEA
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SNPC2_HUMAN
Sequence: MKPPPRRRAAPARYLGEVTGPATWSAREKRQLVRLLQARQGQPEPDATELARELRGRSEAEIRVFLQQLKGRVAREAIQKVHPGGLQGPRRREAQPPAPIEVWTDLAEKITGPLEEALAVAFSQVLTIAATEPVTLLHSKPPKPTQARGKPLLLSAPGGQEDPAPEIPSSAPAAPSSAPRTPDPAPEKPSESSAGPSTEEDFAVDFEKIYKYLSSVSRSGRSPELSAAESAVVLDLLMSLPEELPLLPCTALVEHMTETYLRLTAPQPIPAGGSLGPAAEGDGAGSKAPEETPPATEKAEHSELKSPWQAAGICPLNPFLVPLELLGRAATPAR
What is the function of this protein?
Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes.  Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes.  Recruits TBP and BRF2 to the U6 snRNA TATA box.
What are the official names of this protein?
snRNA-activating protein complex subunit 2, SNAPc subunit 2, Proximal sequence element-binding transcription factor subunit delta, PSE-binding factor subunit delta, PTF subunit delta, Small nuclear RNA-activating complex polypeptide 2, snRNA-activating protein complex 45 kDa subunit, SNAPc 45 kDa subunit.
What are the subcellular locations of this protein?
Nucleus.
Protein: RR8_DIOEL
Sequence: MGRDTIANIITSIRNADMDKKGTVRIASTNITENIVKILLREGFIENVRKHQENQRFFLVSTLRHRRTSKGVYRTILKRISRPGLRIYSNYQRIPKILGGIGIVILSTSQGIMTDREARLKKIGGEILCYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MURA_CAUSK
Sequence: MDRIAITGGAQLNGIIPVSGAKNSAIKLMAASLLTDQPLRLTNMPRLADTKFLGKLLTRLGAQVDEREGLDGSETVLHAAEITSGFAPYDLVRQMRASFNVLGPLIARTGQAKVSLPGGCTIGARPVDLHLQALEALGAKIDLHEGYVYAQAPRGLKGAEITFPFVSVGATEHAMLAAVLADGVTHIHNAACEPELLDLQICLNAMGAKVEGAGTPTITITGVAKLHGATHSVIPDRIEMGTYAVAAAMAGGEVQLTRARPELIDSLLVKLEEAGAGVVRTEDGVIIKRDGTRLNAVDVETQPYPGFATDLQAQFMALMTTAKGESRIRETIFENRFMHAPELMRLGADISVSGGEAIVRGVDRLEGAEVMATDLRASVSLVIAGLVARGETTVSRIYHLDRGFERLEEKLGACGAQVRRIKGDAEGGPDHD
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIE_LISMF
Sequence: MRAELAVYFIAGTQDIVRGTLPGVLEEALKAGITCFQYREKGAGSLQTASERKEMALECQQLCTKYQVPFIINDDVALALEIGADGIHVGQNDEEIRQVIASCAGKMKIGLSVHSVSEAEEAERLGAVDYIGVGPIFPTISKADAESVSGTAILEEIRRAGIKLPIVGIGGINETNSAEVLTAGADGVSVISAITRSDDCYSVIKQLKNPGYPS
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: MIAA_LACLM
Sequence: MKNNKVLVVVGPTAVGKTALGIDLAIKMNGEIISGDSQQVYQGLDIGTAKVTKAEQALAVHHLIDVRKWTENFSVHDFVMEANRLIEEIIERGNVPIIVGGTGLYIQSLIEGYHLGGQENHQAMMELRETLLALTDEELFEKVLKLNPNFPELNRRRAIRFLELQTFGSTDENSGSDYNFLLIGLNAERKVLYERINQRVEQMMSEGLLSEARSLFEKAPDAQAAKGIGYKEFFPYFSGEISLEDAVELVKRNSRRYAKRQLTWFRNRMEVEFEDVFSETYPDSVFEKVTQFLN
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: APT_STRT2
Sequence: MKLEDYIATIENYPKEGVTFRDISPLMADGNAYSYAIREIVQYATDKKIDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPRKVISVDYEKEYGVDTLCMHADAIKPGQRVLIVDDLLATGGTVKATIEMIERLGGVVAGCAFLIELDGLNGREAIEGYDAKVLMNFPG
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOLD_XANC8
Sequence: MLGKTQADQGAAVIRAERLGKTYAEGKMRTPVFDGLDLSVATGETVAIVGASGAGKSTLLHLLGGLDIPTSGEVYVAGRRMSALSDGERGKLRNRSLGFVYQFHHLLPEFTALENVMMPVLLSGQDVSIARGQALQLLESVGLGHRVEHKPSELSGGERQRCAVARALVNKPGCVLGDEPTGNLDDKTAGTVFELMLELNRAQRTSLVLVTHDRSLARRLDRVLELHQGKLRELAPSAV
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL9_STRT2
Sequence: MKVIFLQDVKGKGKKGEIKEVPLGYAQNFLIKKNLAKEATKQAIGELKGKQKSEEKHAAELLAEAKRVKEQLEKEENRLQFTEKVGPDGRTFGSITAKKIAEELQKQFGIKIDKRHIELEHPIRAIGLIEVPVKLHKEVNAQIKLNIKNSAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.