PharMolix/UniProtQA huggingface dataset:
Protein: IF2_BUCAP
Sequence: MVDISLKILSNEMKISIKELIKTLSEISISKTENDCISITEKKNLLKYLESKKKPFLNTFILQRKTRSTLNVFTPGGKNKSVQIEIRKKRMYLKNNKSELEPLLKNKNLLQNKEKNNLKSLKNTISKAKESQKNIDILEESKANINFKNLNKLTKSNVFNKNEKNKSLKKNINFNNHSFYSKKTIKNNTENQKLYKEEKKDYHLTTFIHNRNTEDNRDREIEKNKRNFHRNIKNYRQKKNNKQNNQIKSKKDEVRISKNRKNVKQKNKSILLQQVFKKPESVINRDVVINGAITVCDLANKMAIKSSEVIKNMMNMGIIGTINHVLDQDTAQLIAEEMGHKVILRRENELEELIMKDRDTGNNISLTRAPVVTIMGHVDHGKTSLLDYIRSTKVASSEAGGITQNIGAYHVTTDFGSVTFLDTPGHSAFTGMRSRGVKITDIVVLVVAADDGVKPQTIEAIQHAKEANVPIIVAINKIDKVDSNIDQIKNDLTKYNILSEEWGGENIFVLISAKTGKGIDNLLNAILLQSEILELKAISTGMAEGVVIESFLDKGRGPIATVLVQKGNLKKGDIILCGFEYGRIKVLRNENGKTLKHAGPSMPVEVLGLSKVPFSGEKVTVVRDEKKAKEVASYRKNKSREIKLANQNRSSLENMFKNIKKNDFSELKIIIKSDVQGSLEAISSALFKLSTNEVKVNIIGSGIGGITETDASLALASNAIILGFNVRADASAKKIIDLENLDLRYYSVIYDLLNEVKAAMTGLLSPQYKQNIIGLAEVRNIFKSPKFGLIAGCMVTEGIIKRNNPIRILRNNVVVYEGELESLRRFKEDINEIRNGMECGIGIKNYHDLNIGDVIEVFEVKEIKRIL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLET1_PIG
Sequence: MAVLGSPLLPLRLFLCFGLLFFSASCTDHPDQCMIFNKVTSIHNSRIQVNPKVYESNTVYTVSVPVNNTISSVVMKAVDMHHSVIGFWQKADMNCTSSALYHVKSPHEHVLEAKWLSPASTNINTVELQVFVVDFHKEATASVLKLEKSGTSPALITKLITTKSNTVTTTKPTVITTHTTHKNSANRVFRSPVRDAIQILLAFLTSKLLF
What is the function of this protein?
Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair.  May play a role during trichilemmal differentiation of the hair follicle (By similarity).
What are the official names of this protein?
Placenta-expressed transcript 1 protein.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Apical cell membrane. Note=Localized at the apical membrane of the most differentiated keratinocytes of the outer root sheath (ORS), clustered mainly in planar regions of the plasma membrane at the base of microvilli.
Protein: DEF_MYCVP
Sequence: MAVRPIRIVGDPVLHTATEPVPVGADGSLPADLADLITDMYDTMDAAHGVGLAANQIGVSKRVFVYDCADERKKTTRRRGVVINPVLETSEIPETMPDPEDDDEGCLSVPGESFPTGRADWARVTGLDADGTPITLEGTDLFARMLQHETGHLDGFLYLDRLIGRNARSAKKTVKSHGWGVPGLSWMPGEDPDPFGH
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: RS17_GLAP5
Sequence: MTDKIRTVQGKVVSDKMDKSFVVAIERTVKHPIYGKFIRRTTKLHVHDENNEAKLGDVVEVKECRPLSKTKSHTLVRVVEKAVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: RL34_BEII9
Sequence: MKRTYQPSKIVRKRRHGFRARMATVGGRKVLAARRARGRKRLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: TMA16_HUMAN
Sequence: MPKAPKGKSAGREKKVIHPYSRKAAQITREAHKQEKKEKLKNEKALRLNLVGEKLQWFQNHLDPQKKRYSKKDACELIERYLNRFSSELEQIELHNSIRDRQGRRHCSRETVIKQTMERERQQFEGYGLEIPDILNASNLKTFREWDFDLKKLPNIKMRKICANDAIPKTCKRKTIITVDQDLGELELNDESSDSDEEMTAVA
What is the function of this protein?
Involved in the biogenesis of the 60S ribosomal subunit in the nucleus.
What are the official names of this protein?
Translation machinery-associated protein 16.
What is the protein family that this protein belongs to?
Belongs to the TMA16 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FEN_METHJ
Sequence: MGVALRDILTDLKRPAETDELKGVAAIDAFNALYQFLSIIRQPDGTPLMDDSGRITSHLSGIFFRTANFLTQGIRPVFIFDGKSPEMKGRTIQERRDVREESKEKWDQAKKEGDLAGAFRYAMSSTAIDAYILSSARQLIQLMGLPVVDAPSEGEAQGAYMVLKGDADYVVSQDYDTLLFGTPVLVRNLTISGKRRLHGRQITVQPERIVLSDVLSTLDITREQLIEIAILTGTDFNPGIRGIGAKTGLKKIKSGEFDSIIREKLPDFDPEPVRSFFLNPPVTDSYTLDPGRIDRDGIRAFLCGEHGFSQDRVDPVLDKISKKEKQKTLESWF
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity.  Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation.  Also involved in the base excision repair (BER) pathway.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA (By similarity).
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
Protein: CLCA_ECO7I
Sequence: MKTDTPSLETPQAARLRRRQLIRQLLERDKTPLAILFMAAVVGTLVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAPEAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGREGPTVQIGGNIGRMVLDVFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAVFIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGMQDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLVFIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQYHLEAGTFAIAGMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAILARTLAKQEAEQLARSKAASASENT
What is the function of this protein?
Proton-coupled chloride transporter.  Functions as antiport system and exchanges two chloride ions for 1 proton.  Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.
What are the official names of this protein?
H(+)/Cl(-) exchange transporter ClcA.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClcA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ERPA_MARN8
Sequence: MATPLFFTDNAVAKVRELIEEEENPDLKLRVFVTGGGCSGFQYGFSFDESQEEDDTVIERDGVKLLVDSMSYQYLVGATIDYQEGLQGSQFVVQNPNASSTCGCGSSFSI
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: END4_SALCH
Sequence: MKYIGAHVSAAGGLANAPARAAEIVATAFALFTKNQRQWRAAPLTPQVIDDFKIACEKYHFSAAQILPHDSYLINLGHPVSEALEKSRDAFLDEMQRCEQLGLTLLNFHPGSHLMQIAQEDCLARIAESINIALAQTEGVTAVIENTAGQGSNLGFEFEQLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPEACEKTFAEFGKIVGFQYLRGMHLNDAKSAFGSRVDRHHSLGEGNIGHDAFRWIMQDGRFDGIPLILETINPDIWAEEIAWLKAQQIAEAMA
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: MDH_ACIB5
Sequence: MKQPVRVAVTGAAGQIGYSLLFRIASGEMLGKDQPVILQLLEVPVEKAQQALKGVMMELDDCAFPLLAGMIGTDDPKVAFKDADYALLVGSRPRGPGMERADLLKVNGEIFIGQGQALNEVASRDVKVLVVGNPANTNAYIAMKSAPDLPAKNFTAMLRLDHNRALTQVAQKAGVAVADIEKLTVWGNHSPTMYADYRFATANGESLKDKINDPAWNKDVFLPTVGKRGAAIIEARGLSSAASAANAAIDHMRDWALGTNGKWVTMGVPSDGSYGIPEGVMFGFPVTTENGEYKIVQGLEIDEFSRERINFTLNELEEERAAIADMVK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: RL32_FLAJ1
Sequence: MAHPKRKTSKTRRDKRRTHYKATVAQIATCPITGEAHLYHRAYWHEGKMYYRGQVVIDKSEAVA
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: RL15_BRASB
Sequence: MKLSDIADNAGARKKRMRVGRGIGSGKGKTSGRGGKGQTARSGVRIKGFEGGQMPMHRRLPKRGFNNIFALDFVEINLDRIQQAIDAKKLDAGSVINAEALVKSGALRRAKDGVRLLGRGEITAKVNIEVHGASKSAIAAVEKAGGTVKLLAPAKDEGEAA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: SFH1_ARATH
Sequence: MAETKPEIEMSEEERKIVKISSLKKKAINASNRFKNSFKKKGRRSSSRVMSVPIEDDIDAEDLQALDAFRQALILDELLPSKLDDLHMMLRFLRARKFDIEKAKQMWSDMIQWRKDFGADTIIEDFDFEEIDEVMKHYPQGYHGVDKEGRPVYIERLGQIDANKLLQVTTMDRYVKYHVKEFEKTFKVKFPSCSVAANKHIDQSTTILDVQGVGLKNFSKSARELLQRLCKIDNENYPETLNRMFIINAGSGFRLLWSTVKSFLDPKTTAKIHVLGNKYHSKLLEVIDASELPEFFGGACTCEDKGGCMRSDKGPWNDPEVLKIAINREAKCSPISEDEHKHVDQGRSTSGFESLERIKKKTDEDNVYEKQIATIDKSMDMAWLAKTQKAENFPISKGLECYVRKGAPKKGDGLLVGGVMAFVMGIVAMVRLSKDVPRKLTEAALYGNSVCYEESTKSKQNQGQFAAPVSSSEYMLMVKRMAELEDKCMFLDLKPAHVESEKEEKLQAALNRVQVLEQELTETKKALEEALVSQKEILAYIEKKKKKKKLFFGF
What is the function of this protein?
Required for transport of secretory proteins from the Golgi complex (By similarity).  Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro.  Plays a role in root hair tip elongation as a key regulator of polarized membrane trafficking.  May promote the PtdIns(4,5)P2 synthesis and organization in root hair membrane.
What are the official names of this protein?
Phosphatidylinositol/phosphatidylcholine transfer protein SFH1, Phosphatidylinositol transfer protein 1, AtPITP1, Protein CAN OF WORMS1, Protein SEC FOURTEEN HOMOLOGS 1, AtSFH1, Protein SHORT ROOT HAIR 1.
What is the protein family that this protein belongs to?
Belongs to the SFH family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein.
Protein: PAFA_ACIC1
Sequence: MDRRIFGLENEYGVTCTFHGQRRLSPDEVARYLFRRVVSWGRSSNVFLRNGARLYLDVGSHPEYATPECDNLVDLVVHDKAGERTLEGLLVDAEHRLREEGITGDIYLFKNNTDSAGNSYGCHENYLVTRQGEFSRLADVLIPFLVTRQLICGAGKVLATPRGAVYCLSQRAEHIWEGVSSATTRSRPIINTRDEPHADAERFRRLHVIVGDSNMAEPSTLLKVGSTDIVLRMIEAGVVLRDLSLENPIRAIREVSHDPTGRRRIRMANGREASALEIQEEYLSKAQEFLERRGTDAVTKRVLDLWERTLRAVRTGDLSLVDREIDWVIKYRLIEAYRARHDLPLSSPRVAQIDLAYHDVKRTRGLYYLLERKGAVERVAHDVQIFEAKSTPPQTTRARLRGEFIRHAQEKRRDFTVDWVHLKLNDQAQRTVLCKDPFRSVDERVEKLIASM
What is the function of this protein?
Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation.  This tagging system is termed pupylation.  The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
What are the official names of this protein?
Pup--protein ligase, Proteasome accessory factor A, Pup-conjugating enzyme.
What is the protein family that this protein belongs to?
Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
Protein: CISY_RAT
Sequence: MALLTAAARLLGAKNSSCLVLAARHASASSTNLKDILSNLIPKEQARVKTFRQQHGKTVVGQITVDMMYGGMRGMKGLVYETSVLDPDEGIRFRGYSIPECQKLLPKAKGGEEPLPEGLFWLLVTGQMPTEEQVSWLSQEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAITALNSESNFARAYAEGINRTKYWELIYEDCMDLIAKLPCVAAKIYRNLYREGSSIGAIDSKLDWSHNFTNMLCYTEPQFTELMRLYLTIHSDHDGGNVSAHTSHLVGSALSDTYLSFAAAMNGLAGPLHGLANQEVLVWLTQLQKEVGKDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYSCQREFALKHLPKDPMFKLVAQLYKIVPNILLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTDGLMKFVDSKSG
What are the official names of this protein?
Citrate synthase, mitochondrial, Citrate (Si)-synthase.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: GATA_BDEBA
Sequence: MDLTFASLSEISEAVNNRSISAKEVTLHFLKRIENLNPKLNAFTSLNPQAVQEAEAVDARIANGEDVGLLAGVPFGIKEMFCTKGLTTTAGSKILENFVPPYDATAVARLKKSGIVVMGKLNQDEFAMGSSNETSFHGVVKNPWDLERVPGGSSGGSAAAQASRLVAGTLGTDTGGSIRQPASFCGIVGVKPTYGRVSRYGIVAYASSLDQAGPMVSSVRDAALTLEVISGFDPQDSTTTQKQVPAWSQNLKADVKGMKIGLMKEYMTGALDPDVQKTVENSVDTLKQLGAEIVEVSVPMTAFAVPVYYLVAASEASSNLSRYDGVKYGYRAEFKNLSAVDLEEFYSQTRGQAFGAEVKRRIMLGTYCLSSGYYDAFYNKAGQVRRLIMEQYLEAFKKCDVILSPVTTAPAFKIGERVSDPLAMYLNDIFTTSTNLAGLPGMSVPFGQSQSGLPIGIQLTAGHFEEQKMLNVAFALEGASLVKGKHPHVI
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: SSRP_MESH2
Sequence: MEILIKNKRANFDYEIIDRFTAGIVLLGWEVKSIQAKNISLVGAFCYFKGHELFLSNAKISEYKGSRGQTDRSRKLLMHKHELKKILKEKITRKLAIIPLFIGQKNRKIKLEIALAKGKTKLDKRNLIKERDQKREAAKFLKNYY
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: MTFA_SALHS
Sequence: MIKWPWKAQEITQNEDWPWDDALAIPLLVNLTAQEQARLIALAERFLQQKRLVALQGFELDSLKSARIALIFCLPILELGIEWLDGFHEVLIYPAPFVVDDEWEDDIGLVHSQRVVQSGQSWQQGPIILNWLDIQDSFDASGFNLIIHEVAHKLDMRNGDRASGIPFIPLRDVAGWEHDLHAAMNNIQDEIDLVGESAASIDAYAATDPAECFAVLSEYFFSAPELFAPRFPALWQRFCQFYRQDPSQRLRVSADEGDYGEESEH
What is the function of this protein?
Involved in the regulation of ptsG expression by binding and inactivating Mlc.
What are the official names of this protein?
Protein MtfA, Mlc titration factor A.
What is the protein family that this protein belongs to?
Belongs to the MtfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TEG7_VZVO
Sequence: MQTVCASLCGYARIPTEEPSYEEVRVNTHPQGAALLRLQEALTAVNGLLPAPLTLEDVVASADNTRRLVRAQALARTYAACSRNIECLKQHHFTEDNPGLNAVVRSHMENSKRLADMCLAAITHLYLSVGAVDVTTDDIVDQTLRMTAESEVVMSDVVLLEKTLGVVAKPQASFDVSHNHELSIAKGENVGLKTSPIKSEATQLSEIKPPLIEVSDNNTSNLTKKTYPTETLQPVLTPKQTQDVQRTTPAIKKSHVMLV
What is the function of this protein?
Plays several roles during the time course of infection, including egress of virus particles from the perinuclear space and secondary envelopment of cytoplasmic capsids that bud into specific trans-Golgi network (TGN)-derived membranes (PubMed:28356523).  Localizes its binding partner ORF53 to the host trans-Golgi network (TGN) (PubMed:29116592).
What are the official names of this protein?
Tegument protein UL51 homolog, Protein ORF7.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae UL51 family.
What are the subcellular locations of this protein?
Virion. Virion tegument. Host cytoplasm. Host Golgi apparatus.
Protein: GRWD1_HUMAN
Sequence: MAARKGRRRTCETGEPMEAESGDTSSEGPAQVYLPGRGPPLREGEELVMDEEAYVLYHRAQTGAPCLSFDIVRDHLGDNRTELPLTLYLCAGTQAESAQSNRLMMLRMHNLHGTKPPPSEGSDEEEEEEDEEDEEERKPQLELAMVPHYGGINRVRVSWLGEEPVAGVWSEKGQVEVFALRRLLQVVEEPQALAAFLRDEQAQMKPIFSFAGHMGEGFALDWSPRVTGRLLTGDCQKNIHLWTPTDGGSWHVDQRPFVGHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSRREPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAASGADHQITQWDLAVERDPEAGDVEADPGLADLPQQLLFVHQGETELKELHWHPQCPGLLVSTALSGFTIFRTISV
What is the function of this protein?
Histone binding-protein that regulates chromatin dynamics and minichromosome maintenance (MCM) loading at replication origins, possibly by promoting chromatin openness (PubMed:25990725).
What are the official names of this protein?
Glutamate-rich WD repeat-containing protein 1.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus. Chromosome. Note=Present in the nucleus throughout interphase and is detached from chromatin at the onset of mitosis and rebinds at telophase when the pre-replication complexes (pre-RC) is formed (PubMed:25990725).
Protein: PUR7_XYLFT
Sequence: MLTTLLQSDLPGLPLRHCGKVRDVFDIPRKRLPVDTRSGEYLLIVATDRLSAFDVVLPDPIPGKGEILCQISNFWFQKTEHLMPNHLTGINVASVLPDGIDKTLYIQRAVVTKKLKPVGIEAIARGYLIGSGWKDYQRTGKVSGIQLPDGLQEAEKLPDPIFTPSTKAAVGHHDENIDFDTTVKMVGAELAERVRDATLRIYHFAAKYAAECGILLADTKLEFGTDIDGRLYVMDEMLTPDSSRYWPIDEYQVGTSPPSYDKQLVRNYLETLDWDKTAPGPTLPQDIIDRTRAKYTEALQRLAGINID
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: PIMT_ALIF1
Sequence: MLNSRSELLDQFLRQQGIRDEAILAAIRELPRERFIPEALSHQAYQNNALPIGEGQTISQPYIVAKMTELLELTPTSNVLEVGTGSGYQTAVLAKLVEHVNSIERIKSLQWNAKRLLKQLDIYNVSTKHGDGWKGWESKAPFDAIIVTAAAESIPNDLLFQLKDNGHLVIPIGEESQQLLRITRQGEEFFSEVIEEVRFVPLVAGELA
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPC44_MYCTU
Sequence: MRALLDVNVLLALLDRDHVDHERARAWITGQIERGWASCAITQNGFVRVISQPRYPSPISVAHAIDLLARATHTRYHEFWSCTVSILDSKVIDRSRLHSPKQVTDAYLLALAVAHDGRFVTFDQSIALTAVPGATKQHLATL
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  An RNase.  Its cognate antitoxin is VapB44 (By similarity).
What are the official names of this protein?
Ribonuclease VapC44, RNase VapC44, Toxin VapC44.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
What are the subcellular locations of this protein?
Secreted. Note=Following 6 weeks of nutrient starvation.
Protein: PSAB_HORVU
Sequence: MELRFPRFSQGLAQDPTTRRIWFGIATAHDFESHDDITEERLYQNIFASHFGQLAIIFLWTSGNLFHVAWQGNFESWIQDPLHVRPIAHAIWDPHFGQPAVEAFTRGGAAGPVNIAYSGVYQWWYTIGLRTNEDLYTGALFLLFLSTLSLIASWLHLQPKWKPSLSWFKNAESRLNHHLSGLFGVSSLAWTGHLVHVAIPASRGEYVRWNNFLDVLPYPQGLGPLLTGQWNLYAQNPDSSNHLFGTAQGAGTAILTLLGGFHPQTQSLWLTDMAHHHLAIAFIFLIAGHMYRTNFGIGHSIKDLLEAHTPPGGRLGRGHKGLYDTINNSIHFQLGLALASLGVITSLVAQHMYSLPPYAFIAQDFTTQAALYTHHQYIAGFIMTGAFAHGAIFFIRDYNPEQNEDNVLARMLDHKEAIISHLSWASLFLGFHTLGLYVHNDVMLAFGTPEKQILIEPIFAQWIQSAHGKTTYGFDILLSSTNGPAFNAGRSLWLPGWLNAVNENSNSLFLTIGPGDFLVHHAIALGLHTTTLILVKGALDARGSKLMPDKKDFGYSFPCDGPGRGGTCDISAWDAFYLAVFWMLNTIGWVTFYWHWKHITLWQGNVSQFNESSTYLMGWLRDYLWLNSSQLINGYNPFGMNSLSVWAWMFLFGHLVWATGFMFLISWRGYWQELIETLAWAHERTPLANLIRWRDKPVALSIVQARLVGLAHFSVGYIFTYAAFLIASTSGKFG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2, PSI-B, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: MFNA_THEKO
Sequence: MFPERGASEEEVLRELEEKTREDLTFDSGKILGSMCTYPHPFAVKVVMKYIDRNLGDPGLHIGSQKIEKEAVDMLANLLGLEKGYGHIVSGGTEANILAVRAMRNLAGIEKPELILPESAHFSFIKAAEMLGVKLVWAELNDDYTVNVKDVEKKITDRTIGIVGIAGTTGLGVVDDIPALSDLALDYGLPLHVDAAFGGFVIPFAKALGYEIPDFDFRLKGVKSITIDPHKMGMVPIPAGGIIFREKKFLDSISVLAPYLAGGKIWQATITGTRPGANALAVWAMIKHLGFDGYKEVVKEKMELARWFASELKKIPGIYLIREPVLNIVSFGSEKLEELEKELKARGWGVSAHRGYIRIVVMPHVKREHLEEFLRDLREIAKRL
What is the function of this protein?
Catalyzes the decarboxylation of L-aspartate to produce beta-alanine.  In vitro, can also catalyzes the decarboxylation of L-glutamate to produce 4-aminobutanoate, but this activity does not seem necessary in vivo.  Shows much higher activity with L-aspartate than with L-glutamate.  Does not decarboxylate L-tyrosine.
What are the official names of this protein?
L-aspartate decarboxylase, ADC.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family. MfnA subfamily.
Protein: RL19_AGRVS
Sequence: MNIIQQLEAEQAATIEAKRTLPEFSPGDTLRVNVRVTEGNRTRVQAYEGVCIARSGGSINESFTVRKISYGEGVERVFPVYSPLVESVEVVRRGKVRRAKLYYLRDRRGKSARIVENTGTRARKLNDSERAALAEEKARLEAEKVAAAQALAAEKAAAEAAEKAAAAEAEAAKAAEGSAE
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: VERU2_PENPO
Sequence: MSYKTNYELYSRGSIDSRRSPPPDELLSPLATLYPHVAALQPQYNPSNCTFTGYRDTGYWAAAYTTQTMDDSMSMRRIDGRPCRFVSKLRRLLSRDELKHRRGSRATARTA
What is the function of this protein?
Part of the gene cluster that mediates the biosynthesis of the neurotoxin verrucosidin, a methylated alpha-pyrone polyketide that inhibits oxidative phosphorylation in mitochondria and thereby causes neurological diseases (PubMed:34093475).  The carbon backbone of verrucosidin is synthesized by the HR-PKS verA, and further modified by the other verrucodidin cluster enzymes (Probable).
What are the official names of this protein?
Verrucosidin biosynthesis cluster protein U2, Cluster 4 protein U2.