PharMolix/UniProtQA huggingface dataset:
Protein: PANE_CAUVC
Sequence: MTSIAVIGPGAVGGTLAAWLAQKPDHVVTVCVRTPFEALAVETPEGAISATPRVATSPESLAPVDWVLVTTKTYDTDATWTWLDALVGPQTRVAILRNGVEHVAPFVGKIAAERLVPAVVDIPAERSAPGRMLQRRNGWIKVPVGPAGEAFAALFAHTPIELHVVEDFVTEAWKKLALNCAGAVNALVLKPAGIAHDEGAAQVMRSLVRECVAVGRAEGADLSDDLPDQVIAGYRAADPGSVNSLHADRAAGRAMELDARNGVIVRRGAAHGIATPANAMVVALLNAAAL
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
What are the official names of this protein?
2-dehydropantoate 2-reductase, Ketopantoate reductase, KPR.
What is the protein family that this protein belongs to?
Belongs to the ketopantoate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_SHISS
Sequence: MAIDENKQKALAAALGQIEKQFGKGSIMRLGEDRSMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDPIYARKLGVDIDNLLCSQPDTGEQALEICDALARSGAVDVIVVDSVAALTPKAEIEGEIGDSHMGLAARMMSQAMRKLAGNLKQSNTLLIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRIGAVKEGENVVGSETRVKVVKNKIAAPFKQAEFQILYGEGINFYGELVDLGVKEKLIEKAGAWYSYKGEKIGQGKANATAWLKDNPETAKEIEKKVRELLLSNPNSTPDFSVDDSEGVAETNEDF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXK_CUPMC
Sequence: MAAPQHTLADFVTDQWQRRSWFTWLMWPLSLLFGLIARIRRYGYQQGWFKSTRLPMPVIVVGNVTVGGTGKTPAVIALAHALAEAGLRPGVVSRGYGVKLNHPRRVKPTSKAADVGDEPLLIARAADVPVWVFPDRALCTQAMLVSHPGVNVLLLDDGLQHYKLQRDFEIVMFDTRMGGNGMMLPAGPLREPLTRPRDATLINDPNFRATPDKPDVYGMRLELDEAWQLNDPTMSCDVSKFADKRVLAAAGIGHPERFFASLRQAGLSPATLPLPDHYDFVQDPFADNPAALEADVILITEKDAVKCERFDDPRIWVVPTTPVIDAGLIDKIRRVVQARNPAIATPVTVGQSTATGMADGLDKEHQDGQPAA
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: RL27A_EUPCR
Sequence: MTHSKRNTRKLRGHVSHGHGRVGKHRKHPGGRGMAGPEHHHRINVFKYHPGHIGKHGMRHFHLMRNQYYCPSINLSKLWSLVTEEERQKAQTDKSKVILIDVVKHGYYKVLGKGLLPEVPLVVKAKLFTPTAEKRIKQVGGACVLRAQ
What are the official names of this protein?
60S ribosomal protein L27a, L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: FABI_RICFE
Sequence: MTTGLLQGKKGLITGIANNMSISWAIAQLAKKHGAELWFTYQSEVLEKRVKPLAEEIGCNFVSELDVTNPKSISNLFDDIKEKWGSFDFLLHGMAFADKNELKGRYVDTSLENFHNSLHISCYSLLELSRSAEALMHDGGSIVTLTYYGAEKVIPNYNVMGISKAALEASVKYLATDLGENNIRVNAISAGPIKTLASSAIGDFSTMLKSHAATAPLKRNTTQEDVGGAAVYLFSNLSKGVTGEIHYVDCGYNIMGSNKL
What is the function of this protein?
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).  Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity).
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI, ENR, NADH-dependent enoyl-ACP reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Protein: SWS2_YEAST
Sequence: MVVHILGKGFKGKEVIKIALASKFYGIGKTTAEKICSKLGFYPWMRMHQLSEPQIMSIASELSTMTIEGDARAIVKDNIALKRKIGSYSGMRHTLHLPVRGQHTRNNAKTARKLNKIDRRGIHTFSQAKVQHNPSLWSCIFGK
What is the function of this protein?
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain.  The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
What are the official names of this protein?
37S ribosomal protein SWS2, mitochondrial, Mitochondrial small ribosomal subunit protein uS13m, Sick without securin protein 2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
What are the subcellular locations of this protein?
Mitochondrion. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1.
Protein: Y487_BRUC2
Sequence: MTTHRKPSQEQGFLNGQFLLAMPGMSDERFARSVVYICAHSDEGAMGFIINQLQPVQFPDLLRQIGVIGEEDLIILPDRAQHMVVRNGGPVDRTRGFVLHSDDYMVDSTMPVSDDVCLTATVDILRAIYGGGGPERALMALGYSGWAPGQLEMEVAENGWLTCDAPLDMLFDSDIEGKYSRLMLHMGIDMSRLVSDAGHA
What are the official names of this protein?
UPF0301 protein BCAN_A0487.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: SCPA_LISIN
Sequence: MVEMNFKVEAFEGPLDLLLHLIGQLEVDIYDIPMAEITDQYMEFVHTMQEMELDVASEYLVMAATLLAIKSKMLLPKQELEIDYDTLEEEEDPRDALVEKLMEYKRFKEAAKELKEKEAERSFYFSKPPMDLAEYDEGTKVAELDVSLNDMLSAFNKMLRRKKLNKPLHTRITTQEISIDDRMNSVLGKLHQQTNHRLRFDELFEEQTKEQLVVTFLALLELMKRKLVEVEQSASFADLYVQGKGEELS
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein A.
What is the protein family that this protein belongs to?
Belongs to the ScpA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: SYGB_SALTY
Sequence: MSEKTFLVEIGTEELPPKALRSLAESFAANFTAELDNAGLAHGNVEWFAAPRRLALKVANLAESQPDREVEKRGPAIAQAFDAEGKPSKAAEGWARGCGITVDQAERLKTDKGEWLLYRAHVKGESTEALVPNMVATSLAKLPIPKLMRWGASDVHFVRPVHTVTLLLGDKVIPATILGIQSDRVIRGHRFMGEPEFTIDNADQYPQILLERGKVIADYEARKAKIKADAEEAARKIGGNADLSESLLEEVASLVEWPVVLTAKFEEKFLAVPAEALVYTMKGDQKYFPVYDNAGKLLPNFIFVANIESKDPTQIISGNEKVVRPRLADAEFFFNTDRKKRLEDHLPRLQTVLFQQQLGTLRDKTDRIQALAGWIAGQIGADVNHATRAGLLSKCDLMTNMVFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDDLPSNPVACALAIADKMDTLAGIFGIGQHPKGDKDPFALRRAALGVLRIIVEKNLALDLQTLTEEAVRLYGDKLTNANVVDDVIDFMLGRFRAWYQDEGYTVDTIQAVLARRPTRPADFDARMKAVSHFRTLEEASALAAANKRVSNILAKATEPLNDIVHASVLKEAAEIELARHLVVLRDKLQPYFADGRYQEALIELAALRAPVDEFFENVMVNAEEKDIRINRLTLLSKLRELFLQVADISLLQ
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MP63_MYCTO
Sequence: MKLTTMIKTAVAVVAMAAIATFAAPVALAAYPITGKLGSELTMTDTVGQVVLGWKVSDLKSSTAVIPGYPVAGQVWEATATVNAIRGSVTPAVSQFNARTADGINYRVLWQAAGPDTISGATIPQGEQSTGKIYFDVTGPSPTIVAMNNGMEDLLIWEP
What are the official names of this protein?
Immunogenic protein MPT63, 16 kDa immunoprotective extracellular protein, Antigen MPT63.
What are the subcellular locations of this protein?
Secreted.
Protein: SYT_CLOB6
Sequence: MIKITLKDGKVMEFEEGIKISDIAMKISPALYKKALAAKIDGETVDLMTELHKDSSLEILTFEDEMGKWALRHTGAHILAQAVKRLYPEVKLAIGPAIDTGFYYDFEADFTFTPEMLEKIEAEIKKIIKENHKLERFELPREEAINLMKEKNEDYKVELIEDLPEGEVISFYKQGDFTDLCAGPHVPSTGKVKSVKLLSLAGAYWRGDENNKMLQRIYGTAFTKKSELDEYLNMLEEAKKRDHRKLGKELDLFSIHEEGPGFPFFHPKGMIIRNILENFWREEHTKAGYQEIRTPLILNEALWHQSGHWDHYKENMYFTNIDDGDYAIKPMNCPGGILVYKNSMHSYRDLPLRLSELGIVHRHELSGALHGLMRVRCFTQDDAHLYMTKEQIKEEIVGIIKLIDKFYKLFGFEYFVELSTRPEDSMGSDEDWEIATNGLREALDSIGKEYRVNEGDGAFYGPKIDFHLKDCIGRTWQCGTIQLDFQMPERFDLSYIGADGEKHRPVMVHRTIYGSVERFIGILIEQYAGAFPTWLAPVQVKLMNITDAQYDYLKKVEEALKENNIRVEIDTRNEKIGYKIREAQLQKVPYMLILGDKEVEAGKVAVRSRKDGDLGAISLEEFIEKIKNEIKVKTN
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNTP_ECO5E
Sequence: MNITATVLLAFGMSMDAFAASIGKGATLHKPKFSEALRTGLIFGAVETLTPLIGWGMGMLASRFVLEWNHWIAFVLLIFLGGRMIIEGFRGADDEDEEPRRRHGFWLLVTTAIATSLDAMAVGVGLAFLQVNIIATALAIGCATLIMSTLGMMVGRFIGSIIGKKAEILGGLVLIGIGVQILWTHFHG
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Probable manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL10_XYLF2
Sequence: MALNVFQKQEVVKELAGVATKAHSLIVAEYAGITVPQMTAMRKQARESGVYLKVVKNKLAARALGDTEYAVIKEKLIGPLLYAFSLEDPGAAGRLIKEFSKKHDKLKSKAVSLGGVLYPAGHVDVLASLPTRLQALAMLARVLSEPVTLFARAIKAMADDKSETFAVSSPETSEA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: YDIB_SALDC
Sequence: MDVTAKYELIGLMAYPIRHSLSPEMQNKALEKAGLPYTYMAFEVDNTTFASAIEGLKALKMRGTGVSMPNKQLACEYVDELTPAAKLVGAINTIVNDDGYLRGYNTDGTGHIRAIKESGFDIRGKTMVLLGAGGAATAIGAQAAIEGIKEIKLFNRKDDFFEKAVAFAKRVNENTDCVVTVTDLADQHAFTEALASADILTNGTKVGMKPLENESLIGDVSLLRPELLVTECVYNPHMTKLLQQAQQAGCKTIDGYGMLLWQGAEQFELWTGKAFPLDYVKQVMGFTA
What is the function of this protein?
The actual biological function of YdiB remains unclear, nor is it known whether 3-dehydroshikimate or quinate represents the natural substrate.  Catalyzes the reversible NAD-dependent reduction of both 3-dehydroshikimate (DHSA) and 3-dehydroquinate to yield shikimate (SA) and quinate, respectively.  It can use both NAD or NADP for catalysis, however it has higher catalytic efficiency with NAD.
What are the official names of this protein?
Quinate/shikimate dehydrogenase, NAD-dependent shikimate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: RS4_TRIV2
Sequence: MSRYRGPRLRIVRRLGDLPGLTRKSARRAYPPGQHGQNRKKRSEYAIRLEEKQKLRLNYGLTEKQLLRYVRRARRVTGSTGQVLLQLLEMRLDNTVFRLGMAPTIPAARQLVNHGHVTVNGRVVNIASYQCRPGEEIAVRDKAPSRKLVENNLQYPGLANLPSHLEFDKNKLVGKVNGVIEREWVALQVNELLVVEYYSRQA
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: AROC_STRPQ
Sequence: MRYLTAGESHGPSLTAIIEGIPAGLTLHPADIDHELQRRQGGYGRGARMSIETDRVQISSGVRHGKTTGAPITLTVINKDHQKWLDVMAVGDIEETLKLKRRVKHPRPGHADLVGGIKYHFNDLRDALERSSARETTMRVAVGAVAKRILAELGIDMLHHILIFGGITITIPSKLSFRELQERALHSELSIVNPKQEKEIKTYIDKIKKEGDTIGGIIETIVQGVPAGLGSYVQWDKKLDAKLAQAVLSINAFKGVEFGVGFDMGFQKGSQVMDEITWTPTQGYGRQTNHLGGFEGGMTTGQPLVVKGVMKPIPTLYKPLMSVDIDSHEPYKATVERSDPTALPAAGVIMENVVATVLAKEILETFSSTTMSELQKAFSDYRAYVKQF
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: HOX18_ORYSJ
Sequence: MEGEDLGSWLGLGIGGGGYAYGGDDCRRSPSSPSPVQMLFSQHVKEEITRGYDHGRDEEQASGSKIMKGERGARLRVMRSIRNSGGDGSRSRVLSLGDDGGDGGSGGGGGGGTRKKLQLTKEQSTLLEDSFRVHNILSHAQKHELARQLKLKPRQVEVWFQNRRARTKLKQTEVDCEFLKRCCESLTEENKQLKHELMELRRLASPAAAAAGSQLYVQFPRAAAAAMVNVCPSCEKVTVMGGGGGETGKSSSSYSS
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
Homeobox-leucine zipper protein HOX18, HD-ZIP protein HOX18, Homeodomain transcription factor HOX18, OsHox18.
What is the protein family that this protein belongs to?
Belongs to the HD-ZIP homeobox family. Class II subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ADDB_BACAN
Sequence: MSLRFVIGRAGSGKSTLCLHEVQEELKQRPRGETILYLVPEQMTFQTQQALIGSEDVRGSIRAQVFSFSRLAWKVLQEVGGASRLHIDEAGVHMLLRKIVESRKDGLSVFQKAAEQNGFFEHLGSMIAEFKRYNVTPSNVYEMWQQLDAHSSSAEQKLLANKVYDLQLLYDDFERALIGKYLDSEDYLQLLVEKLPQSEYVKGAEVYIDGFHSFSPQELEIVRQLMICGARVTITLTIDEKTLAQPVNELDLFYETTLTYEKIKQVAREEKIEIEKTIPLMEQPRFHSPALAHLEMHYEARPNEKFHGEASVTIHTAANLRAEVEGVAREIRRLVAEENYRYRDIAVLLRNGESYYDVMRTLFTDYNIPHFIDEKRPMSHHPLVECIRSALEIISGNWRYDAVFRCVKTELLYPLDVRKETMREEMDEFENYCLAYGVQGKRWTSEDPWMYRRYRSLDDTNGMITDSEREMEEKINRLRDVVRTPVIRMQKRLKRAGTVMQMCEAVYLFLEELDVPKKLEALRIRAEENGDFLFATDHEQVWEEVMSLLDTFVEMLGEEKMSLSMFTDVMSTGLEALQFANIPPSLDQVLIANIDRSRLSNVKATFVIGVNEGVIPAAPMDEGMLSDEERDVLSAAGIELAPTTRQTLLEEQFVMYQMVTRATEKLYISCPLADEEGKTLLASSFIKKIKRMFPDVKDTFITNDVNDLSRLEQISYVATPEVTLSYVMQQLQTWKRYGFEGNLDFWWDVYNFYVTSDEWKQKSSRVLSSLFYRNRAQKLSTAVSRDLYGDKIKGSVSRMELFNRCAYAHFAQHGLSLRERDIFKLDAPDIGELFHAALKRIADRLLRENRTWADLSIKECEHLSAVVIEEIAPLLQRQILLSSNRHFYLKQKLQQIIFRTSIILREHAKSSGFVPVDLEVPFGMGGTGSLPPMEFSLPNGVKMEVVGRIDRVDKAEDENGTFLRIIDYKSSSKALDLTEVYYGLALQMLTYLDVVTSNAQTWMKKGGTASPAGVLYFHIHNPIVEVKGDASEAEIEKEILKKFKMKGLVLGDADVVRLMDNKLSTGSSDIISAGLKKDGSFSARSSIASEQEFNVLQKYVHHTFENIGKDITEGVIDIAPYKKGNKAACTFCNFKSVCQFDESLEDNQFRTLKDMKDSEAMEKIREEVGGE
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease AddB, DNA 3'-5' helicase AddB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 1 subfamily.
Protein: RIHA_SHIBS
Sequence: MALPILLDCDPGHDDAIAIVLALASPELDVKAITSSAGNQTPEKTLRNVLRMLTLLNRTDIPVAGGAVKPLMRELIIADNVHGESGLDGPALPEPTFAPQNCTAVELMAKTLRESAEPVTIVSTGPQTNVALLLNSHPELHSKIARIVIMGGAMGLGNWTPAAEFNIYVDPEAAEIVFQSGIPVVMAGLDVTHKAQIHIEDTERFRAIGNPVSTIVAELLDFFLEYHKDEKWGFVGAPLHDPCTIAWLLKPELFTTVERWVGVETQGKYTQGMTVVDYYYLTDNKPNATVMVDVDRQGFVDLLADRLKFYA
What is the function of this protein?
Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively.
What are the official names of this protein?
Pyrimidine-specific ribonucleoside hydrolase RihA, Cytidine/uridine-specific hydrolase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family. RihA subfamily.
Protein: EFPL_ECO57
Sequence: MPRANEIKKGMVLNYNGKLLLVKDIDIQSPTARGAATLYKMRFSDVRTGLKVEERFKGDDIVDTVTLTRRYVDFSYVDGNEYVFMDKEDYTPYTFTKDQIEEELLFMPEGGMPDMQVLTWDGQLLALELPQTVDLEIVETAPGIKGASASARNKPATLSTGLVIQVPEYLSPGEKIRIHIEERRYMGRAD
What are the official names of this protein?
Elongation factor P-like protein.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
Protein: NANA_SHIBS
Sequence: MATNLRGVMAALLTPFDQQQALDKASLRRLVQFNIQQGIDGLYVGGSTGEAFVQSLSEREQVLEIVAEETKGKIKLIAHVGCVSTAESQQLAASAKRYGFDAVSAVTPFYYPFSFEEHCDHYRAIIDSADGLPMVVYNIPALSGVKLTLDQINTLVTLPGVGALKQTSGDLYQMEQIRREHPDLVLYNGYDEIFASGLLAGADGGIGSTYNIMGWRYQGIVKALKEGDIQTAQKLQTECNKVIDLLIKTGVFRGLKTVLHYMDVVSVPLCRKPFGPVDEKYLPELKALAQQLMQERG
What is the function of this protein?
Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate.
What are the official names of this protein?
N-acetylneuraminate lyase, NAL, Neu5Ac lyase, N-acetylneuraminate pyruvate-lyase, N-acetylneuraminic acid aldolase, Sialate lyase, Sialic acid aldolase, Sialic acid lyase.
What is the protein family that this protein belongs to?
Belongs to the DapA family. NanA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRN1_CYPCA
Sequence: VIHCDAATICPDGTTCCLSPYGVWYCCPFSMGQCCRDGIHCCRHGYHCDSTSTHCLR
What is the function of this protein?
Granulins have possible cytokine-like activity.  They may play a role in inflammation, wound repair, and tissue remodeling.
What are the official names of this protein?
Granulin-1.
What is the protein family that this protein belongs to?
Belongs to the granulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ABAA_ASPOR
Sequence: MAEWQTECMLPPTQPGFEGVGPHPGRVLQNTSGNIQSYSDTLAHTDPTGRDDHFSHYGFKYPHQPPVPTHPMPTTTGLHPQQVINNRFHTKKLRRLQSLGPNLIGPRRTRSYLKSQKYIEYRARPRRDTGKDGEPVWSDELEDAFQQALEANPPMGRRKWSERGKSYGRNELIAEYIYKTTGKRRSRKQVSSHLQVLDSFLKGDPDWERLVREQPADRSNGQPPSAGPRWRNSLELPFSSHYNSHNYPSYHDSLRPVQSYSGELPPPHVVFHPNLHAEATNINKIYGLSFDMWVSAPNQPGGIESAFHLYTRLQGDQRHPAPPKRLENIPNWRTSFPHLNSVMADVNNPLNCDIILLEANLRLMDDFPPSGSKLGIQLELDFTQPPNGDALTNQMENWSCSTYIYEEGQNIYRARQDLPKQQSNKVKPPFESTWWAKRFTELTEIAKDRQLNELADRQTRDYFRTLTAVQEIRATPSSRRVSNQYPDNSQDDSKRMAILLWQFRQTRSNEVGTTTWRRVTSPSSDRNTIPSPKPVTGIDLPPLSFYANSLARPAPSIYQAPQSHDLVHHNGTSQPQWSMYQPPQDSIFNANGGFDLLNSITKPEGGLHDKTAVTSVLDTYPNLQPEVSQPTSLNGSNGGPGMLSIPDMSLSHTNLNAYNLSGHDNHYGTPQHPGVSVPDNSHVLNNGIFGSSTQSIDDMSQTHAPWPTPTSSITDVGSSNYSHLQFSDHHVPSVSRESHQPNHFEVLLGPDDLIVGSMPGDPGINGAAHGHMNHTYTENNAVEAA
What is the function of this protein?
BrlA, abaA and wetA are pivotal regulators of conidiophore development and conidium maturation (PubMed:19850144).  They act individually and together to regulate their own expression and that of numerous other sporulation-specific genes (By similarity).  Binds to the sequence 5'-CATTCY-3', where Y is a pyrimidine, making both major- and minor-groove contacts (By similarity).  Controls expression of wetA (PubMed:19850144).
What are the official names of this protein?
Conidiophore development regulator abaA.
What is the protein family that this protein belongs to?
Belongs to the TEC1 family.
What are the subcellular locations of this protein?
Nucleus. Note=localizes to the nuclei of phialides and terminal cells of mature conidia (By similarity).
Protein: LPXK_BORPA
Sequence: MNAPRCLRRLLERQWRQGGWLSTLLRPLAALTGLVVARKRNAYLTGARAAWRAPVPVVVVGNIYVGGTGKTPVVIEVVRQLQARGWTPGVVSRGYGVDVGAAPRVGQGQLAAADYGDEPALIARATGAAIAVHPHRPRAVQALLRAHPGVDVVVSDDGLQHLALARDVEIVVQDERGVGNGRLLPAGPLREPAQRLADVDAIVTNAGRPRAAAAPAAGAPRQLAMWLEPTHAQRVTDGATRTLADLAALPPARLAAAAGIGNPARFFQTLEQAGIRPAHTLALPDHYAYAQSPFTALDADLILVTAKDAIKCAALDDPRLWAVQVGTRLSDPDFGDWLSATLRARQP
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: K1B9C_ANEVI
Sequence: MSPKVLAVFVLCAILVVVMAGRTGTETGGNKKDTLQDLKKRTRNCFDRFEKGTCKMAKRNGACEWSDKYEMNCKKTCGLC
What is the function of this protein?
Inhibits voltage-gated potassium channels (Kv1/KCNA).
What are the official names of this protein?
U-actitoxin-Avd9c, U-AITX-Avd9c, Potassium channel toxin avtx-8.
What is the protein family that this protein belongs to?
Belongs to the sea anemone type 1 potassium channel toxin family. Type 1b subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: RSMH_FRATO
Sequence: MHYSVLLQESINDLNINPQGIYIDATFGRGGHSKAILNRLTTGRLIAFDKDLDAISYARENFQFSNFEIVHASFASIYDYCLQHSLLGKIDGIIMDLGVSSPQLDNAARGFSFTHNGPLDMRMDVSKGITASQALEELSVYDLSYIFKVYGEERFAKKIALRIKDYIQQNGSIRTTLELAELIRATIGKKEKKNPATRCFQALRIYVNNELKDLEALLENILAVIKSGGRIAAISFHSLEDRIVKQKFSALINPKQELNRITKMLPQDSSQIKLKWITKKSKANEDELNQNVRSRSAILRVVEKL
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_PSEA7
Sequence: MLQIYNTLSKTKEVFTPLVGNQVRMYVCGMTVYDYCHLGHGRSMVAFDVITRWLRHRGYDLTYVRNITDIDDKIINRANENGEPFDVLTERMIAAMHEDEARLNILKPDQEPRATDHIAGMHAMIQTLIDKGYAYAPGNGDVYYRVGRFAGYGKLSRRRVEDLRIGARIEPGEAKEDPLDFVLWKGAKPGEPSWSSPWGEGRPGWHIECSVMSTCCLGDSFDIHGGGNDLEFPHHENEIAQSEAATGKPYAKSWLHCGMITINGEKMSKSLGNFFTIREVLEKYHPEVVRYLLIASHYRSPINYSEENLREAKAALDRFYNALKGLPEAAPAEAAEHVERFAAAMDDDFNTAGACSVLFELAREVNRLRDSDLPAAAALAARLKQLAGLLGVLQLEPEAFLQAGAEGKVDAAEVEALIQARLEARAAKNWAESDRIRDQLTAMGVVLEDGKGGTTWRLAD
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXK_SALHS
Sequence: MIARIWSGESPLWRLLLPLSWLYGLVSGAIRLSYKLGFKRAWRAPVPVVVVGNLTAGGNGKTPVVIWLVEKLQQRGVRVGVVSRGYGGKAAAYPLLLTPETTTAEAGDEPVLIYQRTGAPVAVAPERAAAVKAILAAHNVQIIITDDGLQHYRLARDIEIVVIDGVRRFGNGWWLPAGPMRERASRLKTVDAAIVNGGVARAGEIPMQLAPGLAVNLRTGARCDVAQLSNIVAMAGIGHPPRFFATLEACGAHPQKCVPLADHQTLSPADVQALVGEGQTLVMTEKDAVKCRAFAEDNWWFLPVDARLSGEQPDKLLEHITSLVR
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: NELFA_MOUSE
Sequence: MASMRESDTGLWLHNKLGATDELWAPPSIASLLTAAVIDNIRLCFHRLSSAVKLKLLLGTLHLPRRTVDEMKAALMDIIQLATLDSDPWVLMVADILKSFPDTGSLNLDLEEQNPNVQDILGELREKVSECEASAMLPLECQYLNKNALTTLAGPLTPPVKHFQLKRKPKSATLRAELLQKSTETAQQLKRSAGVPFHAKGRGLLRKMDTTTPLKGIPKQAPFRSPTTPSVFSPSGNRTPIPPSRTPLQKERGVKLLDISELNTVGAGREAKRRRKTLDTEVVEKPTKEETVVENATPDYAAGLVSTQKLGSLNSEPTLPSTSYLPSTPSVVPASSYIPSSETPPAPPSREASRPPEEPSAPSPTLPTQFKQRAPMYNSGLSPATPAPAAPTSPLTPTTPPAVTPTAQTPPVAMVAPQTQAPAPVQQQPKKNLSLTREQMFAAQEMFKTANKVTRPEKALILGFMAGSRENPCPEQGDVIQIKLSEHTEDLPKADGQGSTTMLVDTVFEMNYATGQWTRFKKYKPMTNVS
What is the function of this protein?
Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II (By similarity).  The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex (By similarity).
What are the official names of this protein?
Negative elongation factor A, NELF-A, Wolf-Hirschhorn syndrome candidate 2 homolog, mWHSC2.
What is the protein family that this protein belongs to?
Belongs to the NELF-A family.
What are the subcellular locations of this protein?
Nucleus.