PharMolix/UniProtQA huggingface dataset:
Protein: YJJG_ECOLI
Sequence: MKWDWIFFDADETLFTFDSFTGLQRMFLDYSVTFTAEDFQDYQAVNKPLWVDYQNGAITSLQLQHGRFESWAERLNVEPGKLNEAFINAMAEICTPLPGAVSLLNAIRGNAKIGIITNGFSALQQVRLERTGLRDYFDLLVISEEVGVAKPNKKIFDYALEQAGNPDRSRVLMVGDTAESDILGGINAGLATCWLNAHHREQPEGIAPTWTVSSLHELEQLLCKH
What is the function of this protein?
Nucleotidase that shows high phosphatase activity toward non-canonical pyrimidine nucleotides and three canonical nucleoside 5'-monophosphates (UMP, dUMP, and dTMP), and very low activity against TDP, IMP, UDP, GMP, dGMP, AMP, dAMP, and 6-phosphogluconate.  Appears to function as a house-cleaning nucleotidase in vivo, since the general nucleotidase activity of YjjG allows it to protect cells against non-canonical pyrimidine derivatives such as 5-fluoro-2'-deoxyuridine, 5-fluorouridine, 5-fluoroorotate, 5-fluorouracil, and 5-aza-2'-deoxycytidine, and prevents the incorporation of potentially mutagenic nucleotides into DNA.  Its dUMP phosphatase activity that catalyzes the hydrolysis of dUMP to deoxyuridine is necessary for thymine utilization via the thymine salvage pathway.  Is strictly specific to substrates with 5'-phosphates and shows no activity against nucleoside 2'- or 3'-monophosphates.
What are the official names of this protein?
Pyrimidine 5'-nucleotidase YjjG, House-cleaning nucleotidase, Non-canonical pyrimidine nucleotide phosphatase, Nucleoside 5'-monophosphate phosphohydrolase, dUMP phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. YjjG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIF3G_CRYNJ
Sequence: MADSKQSNRDWAADDVDADELPPTTESTDANGITTIVSWKYNADDQKVKVTRRVRRRLQVSTVTQTMAERKQWPKFGLDKGKPPGPDRKTTIIGENLHFKIAPISKIQRVEPEPETAVKAPTGKAVVCRLCSGQHYTARCPFREQLAAIDNLNADGAEEEQVVVSGTLAAKGAGETGGKYVPPSQRAGATGAGDSMFRARDELPTLRVTSLSIDAEEDDLRALFQPFAKNGKLGRANIVRDRNTRVSKGLAFVSFESKRDAEAAMAHLNGRGYDSLILEVAWSQPRGERT
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.  This subunit can bind 18S rRNA.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit G, eIF3g, Eukaryotic translation initiation factor 3 RNA-binding subunit, eIF-3 RNA-binding subunit, Translation initiation factor eIF3 p33 subunit homolog, eIF3 p33 homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit G family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPF_RHOPB
Sequence: MNELANRSFSKMNGIGNEIVVLDLRDHPVAVSAADARAIASEVPYDQLMVLQPPRTPGTEAFVRIYNNDGSESSACGNGMRCVARQVFATSASDALTFETRAGLLNCWRPAPNLYTVDMGPPKLGWKDIPLAEEFRDTRSIELQIGPIDAPVLHTPSVVSMGNPHAIFWVDDVNAHDLARFGPLLENHPIFPERANITLAQIVDRDHIVIRTWERGVGLTKACGSAACATAVAAARLRRVNRVVHITLPGGELGIEWRASDDHVLMTGPAAFEFEGRFDPAVFAAAAS
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_LISIN
Sequence: MVMTDPIADFLTRIRNANMVKHDKLELPASKIKKEIAEILKREGFIRDVEYIEDDNAGTIRVFLKYGATGERVITGLKRISKPGLRVYAKSTEVPKVLNGLGIAIVSTSQGVLTDKEARAKQVGGEVLAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: SYA_SALAI
Sequence: MKTAEIRRRYLAHFEANGHAVVPSAPLPAISDPNLLFVAAGMMQFVPYFLGQQTAPYKRAVSVQKCLRTPDIDEVGKTSRHGTFFQMNGNFSFGDYFKDEAIPLAWDLATKSVDAGGFGLDPERIWPTVYLDDDEAYEVWRSVGVPADRIVRRGKADNFWSMGIPGPCGPCSELFYDRGPEYGLEGGPAVDEDRYLEFWNLVFMQFERGPGTGKEDYPILGDLPAKNIDTGMGLERMASILQGVDNLYEIDEVRPILDRAAELTGKRYGAHSGHVASESHPDDVRLRVVADHVRTALMLIGDGVTPSNEGRGYVLRRIMRRAIRSIRLLGWQERAMPELLPVARDCMSPSYPELAADFGRIADYAYAEEDAFLSTLRAGTTILDTAIAESRTAGRRAISGAQAFQLHDTYGFPIDLTLEIANEQGMQVDAEGFRRLMADQRARAKADAQARKTGHVDLSAYRTVLDEGGPVTFTGYHEVSRESTVRAVLGEAGPRAAAVEGDTVELVLDTTPFYAEGGGQQPDLGVITVGGGQVEVLDVQQPVPGLIVHRARVLRGEVRAGETGFAEIDASRRRAISRSHTATHLVHQTMRNFLGESATQAGSLNAPGRLRFDFNTPTGVAPSVLRDVEQQVNEALLADLEVRAFVTSLAEARRIGAMALFGEKYGEQVRVVEVGDYARELCGGTHVARSGQLGLVKILSESSIGSGVRRVEALVGIDAFNFLAREHLLVARLAELYRVPSDQVADRVEQTVSQLRDAEKELEKLRAQLVLGGAAALAAQATEVRGVAYVGTEAPEGASGNDVRTLAQEIRGRIDPARPAVVAVAARSNGKASLVVAVNQAARSRGLSAADLVKAAFAGRGGGSPELAQGGGLPAAEAPGLLRTVENAIAGA
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DGR1_YEAST
Sequence: MQVGFVSQTNCRSFPACIVFLFQMSQRQRSFNANLRVFKSKCKKIYIG
What are the official names of this protein?
2-deoxy-glucose resistant protein 1, mitochondrial.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: FLGB_CERSP
Sequence: MTGFRDQLGVHAQALVLRETRNNLLTSNIANAATPHYKARDIDFGAELARASGNGTVRTTEARHFAAGGPAARGEALYRDPVSPSLDGNTVEMAVEQMEFAENTLRYQTSLALLNRRISGLMTAIKGE
What is the function of this protein?
Structural component of flagellum, the bacterial motility apparatus.  Part of the rod structure of flagellar basal body (By similarity).
What are the official names of this protein?
Flagellar basal body rod protein FlgB.
What is the protein family that this protein belongs to?
Belongs to the flagella basal body rod proteins family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: PTN20_RAT
Sequence: MSSPGNVRQKHGRDNDEHEGDSDDLNLQKSLPSSSQQKTPTKPVFGNKVNSESVKTSHHMSFSNKYDLVFPEPVESDNDETLWDVRDLSHRNRWSSVDPESAGPSKTVSTVLSESSTDTAVSERELTQLAQIRPLIFNSSSRAALRDCLKALQKKEELDIIREFLELEEMIPPDDFKSGYELQNRDKNRYRDILPYDSTRVPLGKNKDYINASYIRIVNHEEEYFYIATQGPLPDTIEDFWQMVLENNCNVIAMITREIEGGVIKCCSYWPVSLKEPLEFKHFHVLLENFQITQYFVIRIFQIVKKSTGKSHSVKHLQFIKWPDHGTPASADFFIKYVRYVRKSHITGPLLVHCSAGVGRTGVFICVDVVFCTIEKNYSFNIMNIVTQMRKQRFGMIQTKEQYQFCYEIVLEVLQNLLALN
What is the function of this protein?
Tyrosine-protein phosphatase targeted to sites of actin polymerization in response of varied extracellular stimuli.  Has tyrosine phosphatase activity towards various tyrosyl phosphorylated substrates (By similarity).
What are the official names of this protein?
Tyrosine-protein phosphatase non-receptor type 20.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Colocalizes with the microtubule-organizing center and intracellular membrane compartments.
Protein: NUCS_MYCTO
Sequence: MSRVRLVIAQCTVDYIGRLTAHLPSARRLLLFKADGSVSVHADDRAYKPLNWMSPPCWLTEESGGQAPVWVVENKAGEQLRITIEGIEHDSSHELGVDPGLVKDGVEAHLQALLAEHIQLLGEGYTLVRREYMTAIGPVDLLCRDERGGSVAVEIKRRGEIDGVEQLTRYLELLNRDSVLAPVKGVFAAQQIKPQARILATDRGIRCLTLDYDTMRGMDSGEYRLF
What is the function of this protein?
Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
What are the official names of this protein?
Endonuclease NucS.
What is the protein family that this protein belongs to?
Belongs to the NucS endonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_ACTPJ
Sequence: MKIILLGAPGAGKGTQAQFMMNKFGIPQISTGDMFRAAIKEGTELGKQAKALMDEGKLVPDELTVALVKDRIAQPDCANGFLLDGFPRTIPQADALKDSGVKIDLVLEFDVADEVIVERMSGRRVHQPSGRTYHVVYNPPKVEGKDDVTGEDLIIRQDDKPETVLERLAIYHKQTKPLIAYYTAEAEAGNTRYERLDGTKPVEEVSAELAKILG
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAFA_SHIBS
Sequence: MHATTVKNKITQRDNYKEIMSVIVVVLLLTLTLIAIFSAIDQLGISEMGRIARDLTHFIINSLQD
What is the function of this protein?
Connects the signal transduction between the two-component systems EvgS/EvgA and PhoQ/PhoP, by directly interacting with PhoQ and thus activating the PhoQ/PhoP system, in response to acid stress conditions.
What are the official names of this protein?
Two-component-system connector protein SafA.
What is the protein family that this protein belongs to?
Belongs to the SafA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: NUOL_PSEAE
Sequence: MNLLPLTFLFPLVGFLLLSFSRGRWSENLSALVGVGSVGLSALSAAWAIFSFHSSPPEGGAYSLVLWQWMAAGDFSTNFTLYLDGLSVTMLGVVTGVGFLIHLFASWYMRGETGYSRFFAYTNLFIASMLFLVLGDNLLFLYFGWEGVGLCSYLLIGFYYSNRNNGNAALKAFIVTRVGDVFMAFGLFILFQQFGTLNIQELLVLAPQKFPEGNLWLTLATLALLGGAVGKSAQLPLQTWLADAMAGPTPVSALIHAATMVTAGVYLIARCHGLFTLAPDILELVGIVGAVTLVLAGFAALVQTDIKRILAYSTMSQIGYMFLALGVGAWDAAIFHLMTHAFFKALLFLASGAVIVACHHEQNIFKMGGLWKKLPLAYASFVVGGAALAALPFLTAGFYSKDEILWEAFASGHRELLIAGLVGAFLTSIYTFRLIFVAFHGEPKTEAHAGHGISHWLPLSVLIVLSTFVGALITPPLAGVLPESVGHAGGEAKHSLELASGAIAIAGILLAALLFLGQRRFVSALAKSAPGRFFGTWWYHAWGFDWLYDKLFVKPYLLLCQLLGRDPIDRTLGVVPFSVRGGHNLLSLTENGRLRWYAASLVGGAAILLGALLLA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit L, NADH dehydrogenase I subunit L, NDH-1 subunit L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KADA_THEAC
Sequence: MRSVITGVAGVGKTTVLDIVSKETGIKIVNYGTLMFDLAKKRGLVENRDQMRKLSRDIQIDLQKNAATEIGRMEDVIVDTHMSIKTPFGYLPGLPEWVLREINASAFIIIEADPELILRRRQNDPTRARDEDSVESIREHQEINRAFAAAYSIFSGATVKIITNEEGKPDKAAHDIIKVIAVD
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase.
What is the protein family that this protein belongs to?
Belongs to the archaeal adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FKBP_CRYNJ
Sequence: MGVTVENISAGDGKTFPQPGDSVTIHYVGTLLDGSKFDSSRDRGTPFVCRIGQGQVIRGWDEGVPQLSIGQKANLICTPDYAYGARGFPPVIPPNSTLKFEVELLKIN
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
FK506-binding protein 1, FKBP, Peptidyl-prolyl cis-trans isomerase, PPIase, Rapamycin-binding protein.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. FKBP1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVH_AQUAE
Sequence: MADTLGKSELEVIKPQKREIRKGQVRKHIITVKVRNEMGVLARIATLIAGKGYNIEGLSVGETHEKGISRMTIEVIGDDIVIEQVVKQLRRLIDTLKVSDLTDVPHVERELALIKVYTPSSRARDEVLRITEIFRGKVVDVSPDTYTIEVTGDEDKINAMIELLKPFGIKEMARTGKVAMRREMSIKEEENE
What are the official names of this protein?
Acetolactate synthase small subunit, Acetohydroxy-acid synthase small subunit, AHAS, ALS.
What is the protein family that this protein belongs to?
Belongs to the acetolactate synthase small subunit family.
Protein: CSRA_GLAP5
Sequence: MLILTRKIGESLLIGDDVEITVLSIRGSQVKLGVKAPKEISVHREEIYQRIKVLADENPSE
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STX1A_MOUSE
Sequence: MKDRTQELRTAKDSDDDDDVTVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSSISKQALSEIETRHSEIIKLETSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSDTKKAVKYQSKARRKKIMIIICCVILGIIIASTIGGIFG
What is the function of this protein?
Plays an essential role in hormone and neurotransmitter calcium-dependent exocytosis and endocytosis (PubMed:17502420, PubMed:28596237, PubMed:28031464).  Part of the SNARE (Soluble NSF Attachment Receptor) complex composed of SNAP25, STX1A and VAMP2 which mediates the fusion of synaptic vesicles with the presynaptic plasma membrane.  STX1A and SNAP25 are localized on the plasma membrane while VAMP2 resides in synaptic vesicles.  The pairing of the three SNAREs from the N-terminal SNARE motifs to the C-terminal anchors leads to the formation of the SNARE complex, which brings membranes into close proximity and results in final fusion.  Participates in the calcium-dependent regulation of acrosomal exocytosis in sperm (PubMed:12101244).  Also plays an important role in the exocytosis of hormones such as insulin or glucagon-like peptide 1 (GLP-1) (PubMed:17502420, PubMed:28596237, PubMed:28031464).
What are the official names of this protein?
Syntaxin-1A, Neuron-specific antigen HPC-1.
What is the protein family that this protein belongs to?
Belongs to the syntaxin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type IV membrane protein. Synapse, synaptosome. Cell membrane. Note=Colocalizes with KCNB1 at the cell membrane.
Protein: GCSH_ACIBT
Sequence: MNHPSELKYARTHEWVKIEGDLVITGITDHAQDELGDLVYVETPEVGSQVTAGEQAGVVESVKTASDIHAPVSGTVVEVNTDLEDDPDFVNEDPYGKGWIYKIKPDNIADVEKLLTNAEYEAGL
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: LSH10_ARATH
Sequence: MSSPRERGKSLMESSGSEPPVTPSRYESQKRRDWNTFGQYLKNQRPPVPMSHCSCNHVLDFLRYLDQFGKTKVHVPGCMFYGQPEPPAPCTCPLRQAWGSLDALIGRLRAAYEENGGPPETNPFASGAIRVYLREVRECQAKARGIPYKKKKKKKPTPEMGGGREDSSSSSSSFSFS
What is the function of this protein?
Probable transcription regulator that acts as a developmental regulator by promoting cell growth in response to light.
What are the official names of this protein?
Protein LIGHT-DEPENDENT SHORT HYPOCOTYLS 10, Protein ORGAN BOUNDARY 10.
What is the protein family that this protein belongs to?
Belongs to the plant homeotic and developmental regulators ALOG protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ABCA5_HUMAN
Sequence: MSTAIREVGVWRQTRTLLLKNYLIKCRTKKSSVQEILFPLFFLFWLILISMMHPNKKYEEVPNIELNPMDKFTLSNLILGYTPVTNITSSIMQKVSTDHLPDVIITEEYTNEKEMLTSSLSKPSNFVGVVFKDSMSYELRFFPDMIPVSSIYMDSRAGCSKSCEAAQYWSSGFTVLQASIDAAIIQLKTNVSLWKELESTKAVIMGETAVVEIDTFPRGVILIYLVIAFSPFGYFLAIHIVAEKEKKIKEFLKIMGLHDTAFWLSWVLLYTSLIFLMSLLMAVIATASLLFPQSSSIVIFLLFFLYGLSSVFFALMLTPLFKKSKHVGIVEFFVTVAFGFIGLMIILIESFPKSLVWLFSPFCHCTFVIGIAQVMHLEDFNEGASFSNLTAGPYPLIITIIMLTLNSIFYVLLAVYLDQVIPGEFGLRRSSLYFLKPSYWSKSKRNYEELSEGNVNGNISFSEIIEPVSSEFVGKEAIRISGIQKTYRKKGENVEALRNLSFDIYEGQITALLGHSGTGKSTLMNILCGLCPPSDGFASIYGHRVSEIDEMFEARKMIGICPQLDIHFDVLTVEENLSILASIKGIPANNIIQEVQKVLLDLDMQTIKDNQAKKLSGGQKRKLSLGIAVLGNPKILLLDEPTAGMDPCSRHIVWNLLKYRKANRVTVFSTHFMDEADILADRKAVISQGMLKCVGSSMFLKSKWGIGYRLSMYIDKYCATESLSSLVKQHIPGATLLQQNDQQLVYSLPFKDMDKFSGLFSALDSHSNLGVISYGVSMTTLEDVFLKLEVEAEIDQADYSVFTQQPLEEEMDSKSFDEMEQSLLILSETKAALVSTMSLWKQQMYTIAKFHFFTLKRESKSVRSVLLLLLIFFTVQIFMFLVHHSFKNAVVPIKLVPDLYFLKPGDKPHKYKTSLLLQNSADSDISDLISFFTSQNIMVTMINDSDYVSVAPHSAALNVMHSEKDYVFAAVFNSTMVYSLPILVNIISNYYLYHLNVTETIQIWSTPFFQEITDIVFKIELYFQAALLGIIVTAMPPYFAMENAENHKIKAYTQLKLSGLLPSAYWIGQAVVDIPLFFIILILMLGSLLAFHYGLYFYTVKFLAVVFCLIGYVPSVILFTYIASFTFKKILNTKEFWSFIYSVAALACIAITEITFFMGYTIATILHYAFCIIIPIYPLLGCLISFIKISWKNVRKNVDTYNPWDRLSVAVISPYLQCVLWIFLLQYYEKKYGGRSIRKDPFFRNLSTKSKNRKLPEPPDNEDEDEDVKAERLKVKELMGCQCCEEKPSIMVSNLHKEYDDKKDFLLSRKVKKVATKYISFCVKKGEILGLLGPNGAGKSTIINILVGDIEPTSGQVFLGDYSSETSEDDDSLKCMGYCPQINPLWPDTTLQEHFEIYGAVKGMSASDMKEVISRITHALDLKEHLQKTVKKLPAGIKRKLCFALSMLGNPQITLLDEPSTGMDPKAKQHMWRAIRTAFKNRKRAAILTTHYMEEAEAVCDRVAIMVSGQLRCIGTVQHLKSKFGKGYFLEIKLKDWIENLEVDRLQREIQYIFPNASRQESFSSILAYKIPKEDVQSLSQSFFKLEEAKHAFAIEEYSFSQATLEQVFVELTKEQEEEDNSCGTLNSTLWWERTQEDRVVF
What is the function of this protein?
Cholesterol efflux transporter in macrophages that is responsible for APOAI/high-density lipoproteins (HDL) formation at the plasma membrane under high cholesterol levels and participates in reverse cholesterol transport (PubMed:25125465).  May play a role in the processing of autolysosomes (By similarity).
What are the official names of this protein?
Cholesterol transporter ABCA5, ATP-binding cassette sub-family A member 5.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCA family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Cell membrane. Note=Localized at cell membrane under high cholesterol levels.
Protein: METN2_BURPS
Sequence: MAQLLDSPGFIERSAAVPHKAAAAPATRDAAAPAAVPGAAVSFELVGKVFDGPRGPAAALREVTLDIARGGVFGVIGRSGAGKSTLLRLVNGLERPTSGAVRVNGVDVGTLDERGLVALRRRIGMVFQHFNLLSAKTVAQNIGLPLKIAGVPKAERARKVDALLDLVGLAAKRDAYPASLSGGQKQRVGIARALVHDPALLLCDEATSALDPETTQSILALLADINRRLGLTIMLITHEMEVIRAVCDTVAVVEQGEVVETGPVWRVFGDPRHGATRALLRTLVHDLPADLAARVRPLDGAAPLPCGAQLLLDVRYTGASGGEPDLGALTAALARNVGDAVHFVHGGLDRIQGRVQGRLVIAASLAARGAAGPDRIAAALAAARRHANRVEVLGYV
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: QUEC_PASMU
Sequence: MQLTNPNRDRKAVVIFSGGQDSTTCLFQAIQDYGVENVEVVTFQYGQRHAIELEKAKWIAQDLGVKQTLIDTSVIKAITQNALMDEQARIEQHGSTPNTFVDGRNALFLLYTAIYAKGQGIQDIITGVCETDFSGYPDCRDVFIKSMNVTLNLAMDYQFHLKTPLMYLTKAQTWQLADELGVLDYIRQHTHTCYMGVEQGCGECPSCVLREKGLREYLSSKSEAEIDV
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: RS7_XANOR
Sequence: MSRKGSTPQRTVLPDPKHGSETIARFINMVMQSGKKSVAEKIVYGAMDVIGEKNPNAIELVQKALDNVAPAVEVKSRRVGGATYQVPVEVRSSRRMALAMRWLIDSARKRGENTMPRKLAAELLDAAESRGGAIKKREETHRMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: SYP_METC4
Sequence: MRLSRYFLPILRETPKEAEIISHRLMLRAGMIRQEAAGIYAWLPLGLRVLNKVCDVVRAEQDRAGAIEILMPTIQAADLWRESGRYEAYGKEMLRLKDRHERELLYGPTAEEVVTEIFRASTRSYKDLPKNLYQISWKFRDEVRPRFGTMRSREFLMKDGYSFDIDQAAARHSYNKVFVSYLRTFERLGLRAIPMRADTGPIGGDLSHEFIILAKTGESEVFCDQAYLDMPVPPPSVDFDDVAGLQGVVDAWTSHYAATDEMHDEAVFAEVPEASRLSARGIEVGHIFYFGTKYSTPMKAVVTGPDGSERPVHMGSYGIGPSRLVAATIEASHDEAGIIWPDAIAPFDVALINLKVGDGACDTACAEIQAALETAGLSVLYDDRDERPGAKFATADLIGLPWQVIVGPKGLAEGKIELKRRASGERETLDPVDLPARIRRL
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSCA_HISS2
Sequence: MALLQIAEPGQSAAPHQHKLAVGIDLGTTNSLVAAVRSGSSEVLRDEQDRLLIPSIVHLTEDQAIVGYEAGQLASQDPQNTIISVKRLIGRSCTDVQQRYPNLPYQFNATENGLPLLKTRRGLLSPVEISAEILKKLTALAEQRLGGELTGAVITVPAYFDDAQRQSTKDAAKLAGLKVLRLLNEPTAAAIAYGLDSGQEGVIAVYDLGGGTFDVSILRLSKGVFEVLATGGDTALGGDDFDHLLAEWIVKKSTVAPQNDREKRQLIEVANQVKVALTTNDKIRISYAEQNLEIMRDEFNFLISGLVKRSLLACRRTLKDANLTPSDILEVVMVGGSTRIPYVREQVGEFFQCTPLTSIDPDKVVALGAAIQADILVGNKPDSEMLLLDVIPLSLGIETMGGLVEKIIPRNTTIPVARAQEFTTFKDGQTAMSVHVLQGEREMVTDCRSLARFTLRGIPAMVAGAARIRVTYQVDADGLLSVTAVEKSTGVQASTQVKPSYGLTDDEIANMLKSSMEHAKEDIQTRLLTEQRVDATRVIESVYSALQQDEDLLDDNELSAVKNALVSLQKLIQEEDSLAIKQGIKMLDQATQEFASRRMDKSIRRALSGQHIEHIK
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: URE3_KOCRD
Sequence: MHLQPKDQEKLLVVVAADLARRRQARGLKLNHPEAIAIITYELLEGARDGRTVAELMSWGSTILSREDVMEGVPEMIPDVQVEATFPDGTKLVTVHDPIR
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.