PharMolix/UniProtQA huggingface dataset:
Protein: PIWL4_HUMAN
Sequence: MSGRARVKARGIARSPSATEVGRIQASPLPRSVDLSNNEASSSNGFLGTSRISTNDKYGISSGDAGSTFMERGVKNKQDFMDLSICTREKLAHVRNCKTGSSGIPVKLVTNLFNLDFPQDWQLYQYHVTYIPDLASRRLRIALLYSHSELSNKAKAFDGAILFLSQKLEEKVTELSSETQRGETIKMTITLKRELPSSSPVCIQVFNIIFRKILKKLSMYQIGRNFYNPSEPMEIPQHKLSLWPGFAISVSYFERKLLFSADVSYKVLRNETVLEFMTALCQRTGLSCFTQTCEKQLIGLIVLTRYNNRTYSIDDIDWSVKPTHTFQKRDGTEITYVDYYKQQYDITVSDLNQPMLVSLLKKKRNDNSEAQLAHLIPELCFLTGLTDQATSDFQLMKAVAEKTRLSPSGRQQRLARLVDNIQRNTNARFELETWGLHFGSQISLTGRIVPSEKILMQDHICQPVSAADWSKDIRTCKILNAQSLNTWLILCSDRTEYVAESFLNCLRRVAGSMGFNVDYPKIIKVQENPAAFVRAIQQYVDPDVQLVMCILPSNQKTYYDSIKKYLSSDCPVPSQCVLARTLNKQGMMMSIATKIAMQMTCKLGGELWAVEIPLKSLMVVGIDVCKDALSKDVMVVGCVASVNPRITRWFSRCILQRTMTDVADCLKVFMTGALNKWYKYNHDLPARIIVYRAGVGDGQLKTLIEYEVPQLLSSVAESSSNTSSRLSVIVVRKKCMPRFFTEMNRTVQNPPLGTVVDSEATRNEWYDFYLISQVACRGTVSPTYYNVIYDDNGLKPDHMQRLTFKLCHLYYNWPGIVSVPAPCQYAHKLTFLVAQSIHKEPSLELANHLFYL
What is the function of this protein?
Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity (By similarity).  Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons (By similarity).  Directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements (By similarity).  Associates with secondary piRNAs antisense and PIWIL2/MILI is required for such association (By similarity).  The piRNA process acts upstream of known mediators of DNA methylation (By similarity).  Does not show endonuclease activity (By similarity).  Plays a key role in the piRNA amplification loop, also named ping-pong amplification cycle, by acting as a 'slicer-incompetent' component that loads cleaved piRNAs from the 'slicer-competent' component PIWIL2 and target them on genomic transposon loci in the nucleus (By similarity).  May be involved in the chromatin-modifying pathway by inducing 'Lys-9' methylation of histone H3 at some loci (PubMed:17544373).  In addition to its role in germline, PIWIL4 also plays a role in the regulation of somatic cells activities.  Plays a role in pancreatic beta cell function and insulin secretion (By similarity).  Involved in maintaining cell morphology and functional integrity of retinal epithelial through Akt/GSK3alpha/beta signaling pathway (PubMed:28025795).  When overexpressed, acts as an oncogene by inhibition of apoptosis and promotion of cells proliferation in tumors (PubMed:22483988).
What are the official names of this protein?
Piwi-like protein 4.
What is the protein family that this protein belongs to?
Belongs to the argonaute family. Piwi subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Probable component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. PIWIL2/MILI is required for nuclear localization (By similarity).
Protein: YCHJ_ECO7I
Sequence: MSQLCPCGSAVEYSLCCHPYVSGEKVAPDPEHLMRSRYCAFVMKDADYLIKTWHPSCGAAALRAELMAGFAHTEWLGLTVFEHCWQDADNIGFVSFVARFTEGGKTGAIIERSRFLKENGQWYYIDGTRPQFGRNDPCPCGSGKKFKKCCGQ
What are the official names of this protein?
UPF0225 protein YchJ.
What is the protein family that this protein belongs to?
Belongs to the UPF0225 family.
Protein: Y1355_NEIG2
Sequence: MNLSNHFLVAMPDMEDAFFSQSVVYICKHDEDGALGIAINKPSPITMDMIFSATGKNIPMRMQHDSVMMGGPVQVERGYVVHTPIGNWQSSIGVSDGIALTSSRDVLENISREGAVDKALISIGYSSWSKGQLERELADNAWLTVPADEHILFDIPYEHRYAAAFAKLGIDPLALFSGAGHA
What are the official names of this protein?
UPF0301 protein NGK_1355.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: ISPD_SERP5
Sequence: MNHSAGTFPPVIAVLPAAGIGSRMQADCPKQYLTIGHQTILEHAIHALLRHPRIPQVIVAIGPDDQQFHQLPIAKDPRVRVTVGGQQRADSVMAGLQLAGEAKWVLVHDAARPCLHAEDLERLLAITEHSEVGGILAAPVRDTMKRAEPGRSTISHTVERQDLWHALTPQLFPLALLKLCLQRAMDDGATVTDEASALEHCGYHPLLVSGRSDNIKVTRPEDLALAAFYLTQLDN
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: DXS_XYLFM
Sequence: MIDSTCYPRLSRIQTPEDLRAFQESELRAVADELRNYLIESVGLSGGHFAAGLGVVELTIALHYLYCTPIDQLVWDVGHQTYPHKILTGRRDKISTVKHQGGLAPFPKREESIYDTFGVGHSSTSISAALGMAIVAQRNGDERKVVAIIGDGAMTAGMAYEALNHAGGMSPAPNLLVILNDNRMSISEAVGGLTKMLGRATGSKALNAIREGGKRIFGDKKTNATARFLRRWEEHWKGMFVPSTLFEEMGFHYTGPIDGHDLPALLGALKTLRTLKGPQLLHVITTKGKGYELAEGDQIGYHAVAPFDPQKGLIKAGAKKQTYTDVFSEWLCDMAAVEPRLLAITPAMREGSGLVRFSQEYPQRYFDVAIAEQHAITLAAGMATQGAKPVVAIYSTFLQRGYDQLVHDVALQKLDVLFAVDRGGVVGPDGATHAGNLDLSFLRCVPNMMLMAPADEAECRKMLSTGFHYSGPVAVRYPRGTGPGVVPSAELDVLPVGVAQLRHSGTRIALLGFGVCVAPAEQVGRRLGLTVVNMRFIKPLDRTLLLELARTHEVFVTIEDNVVAGGAGSGVAELLNAEGIVLPIVHLGLPDAFQQHASREDLLAEAGIDAAGVYAALLSRWPDLAVQNHPLSAVS
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: RF1_COXB1
Sequence: MKPSLIEKLKTLTYRYSEIGGLLSDSTVINDQDRYRELGKEYAQLEPIVKCFQQFQQNEKAIESAEEMQQEKDPELRKLAEEELEQLTLKKEELEDQLKLLLVPKDPNDERNVFLEIRAGTGGNEAAIFAGDLFRMYARYAETKGWRVNIVSAHEGEHGGFKEVIARVIGEGVYSQLKFESGAHRVQRVPVTESQGRIHTSACTVAIMPEVDEIDQIKINPAELRIDTFRASGAGGQHVNRTDSAIRITHLPTGVVVECQDERSQHKNKARAMSLLQSKLLAAERAKQDQEQAAKRKSLVGSGDRSERIRTYNFPQGRVTDHRINLTLYQLDEVIEGDLDPVIGPLIRELQAEQLAELSGE
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GAG_HV1N5
Sequence: MGARASVLSGGELDKWEKIRLRPGGKKQYKLKHIVWASRELERFAVNPGLLETSEGCRQILGQLQPSLQTGSEELRSLYNTIAVLYCVHQRIDVKDTKEALDKIEEEQNKSKKKAQQAAADTGNNSQVSQNYPIVQNLQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVRMYSPTSILDIRQGPKEPFRDYVDRFYKTLRAEQASQEVKNWMTETLLVQNANPDCKTILKALGPGATLEEMMTACQGVGGPGHKARVLAEAMSQVTNPATIMIQKGNFRNQRKTVKCFNCGKEGHIAKNCRAPRKKGCWKCGKEGHQMKDCTERQANFLGKIWPSHKGRPGNFLQSRPEPTAPPEESFRFGEETTTPSQKQEPIDKELYPLASLRSLFGSDPSSQ
What is the function of this protein?
Plays a role in budding of the assembled particle by interacting with the host class E VPS proteins TSG101 and PDCD6IP/AIP1.
What are the official names of this protein?
Gag polyprotein, Pr55Gag.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group gag polyprotein family.
What are the subcellular locations of this protein?
[Gag polyprotein]: Host cell membrane; Lipid- anchor. Host endosome, host multivesicular body. Note=These locations are probably linked to virus assembly sites. The main location is the cell membrane, but under some circumstances, late endosomal compartments can serve as productive sites for virion assembly. SUBCELLULAR LOCATION: [Matrix protein p17]: Virion membrane; Lipid- anchor. Host nucleus. Host cytoplasm. SUBCELLULAR LOCATION: [Capsid protein p24]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p7]: Virion.
Protein: MACIR_XENTR
Sequence: MEVDINGVNRTNNSVPSTTEGSSPSKPDPEKPRCSSTPCSPIRRTVSGYQILHMDANFLVGFTTGEELLKLAHKCATTEENPGESLPAFRSKQLESGLSRSSRIYKARGRQYQPYEIPAVNGRRRRRMPSSGDKCNKAVPYEPYKAVHGPLPLCLLKGKRAHSKSLDYLNLDKMNIKESADTEVLQYQLQHLTLRGDRVFARNNT
What is the function of this protein?
May play a role in immune regulation through regulation of the macrophage function (By similarity).  May also play a role in trafficking of proteins via its interaction with unc119 family cargo adapters (By similarity).  May play a role in ciliary membrane localization (By similarity).
What are the official names of this protein?
Macrophage immunometabolism regulator.
What is the protein family that this protein belongs to?
Belongs to the UNC119-binding protein family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, cilium.
Protein: ALR_CLONN
Sequence: MFKHLRPVWAEINLDNLASNMKHIKELSNTKEIIGIVKADAYGHGALDIVPTLIENGATALAVAVVSEGVELRRGGIECPIMVLGFTPPSLIDMLLKHDIEQTVFSLDYAKELSKAAEKMHKVAKIHIAVDTGMGRIGFLPNEQSIQDVKAISMLPNIKIKGMFSHFSTADEKNKEYSAYQLNQFNKFYEGLKRENVNIETRHISNSAAIMDLPETIFEGVRPGIILYGYYPSNEVDKTKLELKPVMQLKTNVVHIKKIPSGEYISYGRKFKTDRESLIATLPVGYADGYTRLLFGKAKVIINGQLAPVVGRICMDQCMVDITDIKGDIKVGEEVILIGEKNGVKIDADDIAEMLGTINYEVICMISKRVPRVYIKNGEVIKVRNYI
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: CXCR1_RABIT
Sequence: MEVNVWNMTDLWTWFEDEFANATGMPPVEKDYSPCLVVTQTLNKYVVVVIYALVFLLSLLGNSLVMLVILYSRSNRSVTDVYLLNLAMADLLFALTMPIWAVSKEKGWIFGTPLCKVVSLVKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRHLVKFICLGIWALSLILSLPFFLFRQVFSPNNSSPVCYEDLGHNTAKWRMVLRILPHTFGFILPLLVMLFCYGFTLRTLFQAHMGQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTHVIQETCQRRNDIDRALDATEILGFLHSCLNPIIYAFIGQNFRNGFLKMLAARGLISKEFLTRHRVTSYTSSSTNVPSNL
What is the function of this protein?
Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor.  Binding of IL-8 to the receptor causes activation of neutrophils.  This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.
What are the official names of this protein?
C-X-C chemokine receptor type 1, CXC-R1, CXCR-1, High affinity interleukin-8 receptor A, IL-8R A.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SOX3_CAEEL
Sequence: MTDLSCLYPSLLCTEAAKTSYDEDTTSVSSGLSPPGSPVDLQNSLDHVKRPMNAFMVWSRGQRRKMAQDNPKMHNSEISKRLGAEWKQLSEQEKRPFIDEAKRLRALHMKEHPDYKYRPRRKPKSSNLKQQPRLNIAMPTIPPQSLFNYSTAFDSLKTHDLSQYYSSFFQSPVLSGSTYAPYNMMAAYARQAAAVAAASQVSASTTPTAPAT
What is the function of this protein?
Probable transcription factor (PubMed:26153233).  Involved in the terminal differentiation of some neuronal cell types (PubMed:26153233).  Dispensable for neuronal fate commitment during embryogenesis (PubMed:26153233).
What are the official names of this protein?
Transcription factor sox-3.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRXY_ORYSJ
Sequence: MAAFTSTTTAAAASPTPCRPAALVARSSAAPLRSAAPVVVAAGLRRAAAPSRRGATLRVQAKKQTFSSFDELLEKSEKPVLVDFYATWCGPCQYMVPILQEVSEKLGDKIQVVKIDTEKYTSIANRYQIEALPTFIIFKNGKPCHRFEGALPANQLIQQIESALEVAK
What is the function of this protein?
Probable thiol-disulfide oxidoreductase that may participate in various redox reactions.
What are the official names of this protein?
Thioredoxin Y, chloroplastic, OsTrxy.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. Plant Y-type subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LECM_OXYSU
Sequence: MGRFLLVTLSLLVGAFSLNEANSCCCPQDWLPKNGFCYKVFNDHKNWNDAEMFCRKFKPGCHLASIHSNADSADLAEYVSDYLKSDGNVWIGLNDPRKQRTWVWSDRSPTNYYSWNRGEPNNSKNNEYCVHLWALSGYLKWNDTPCKALYSFICQCRF
What is the function of this protein?
Mannose-binding lectin that binds to and agglutinates rabbit (but not human) erythrocytes in a calcium-dependent manner.
What are the official names of this protein?
C-type lectin mannose-binding isoform, CTL, Venom C-type lectin mannose-binding isoform 1.
What is the protein family that this protein belongs to?
Belongs to the true venom lectin family.
What are the subcellular locations of this protein?
Secreted.
Protein: YXIP_BACSU
Sequence: MRRIGLCISLLVTVLVMSACESEGEAQMFADCDQKTVKQTAAKPMSSKKKQDFQALASDRQLAIVFSSMIQVSEAFDYGIGNPEYFVRISMTEEEADIAKENLESIKLENKSLKKQNSEAVALLQKTRNQDMSRIEIQQLTENRAGFFETADSMIKLINQVTPKNAKKTRQQLDQLKKQYTQYSAESIKIMNSIVKKQKADKASFERHLEALLQKQPGQQVRSELY
What are the official names of this protein?
Uncharacterized protein YxiP.
Protein: CASP3_VIGUN
Sequence: MESKKEGVASAPTSPESRRTRSNGKGKTIAEATPPSVTVVSTKVTPSPRGGWRKGAAILDFILRLGAISSAIGAAAVMGNNEQILPFFTQFFQFHVQWDDFPMFQFFVFANGAAVVFLILSLPFSIVCIVRPFAVGPRLLLVIVDIFAMALVIAAASAAAAVVYLAHNGSQDANWIAICQQYTDFCQVTSQAVVASFVAAVFLICLIVLSSVALKKGLKREFGW
What is the function of this protein?
Regulates membrane-cell wall junctions and localized cell wall deposition.  Required for establishment of the Casparian strip membrane domain (CSD) and the subsequent formation of Casparian strips, a cell wall modification of the root endodermis that determines an apoplastic barrier between the intraorganismal apoplasm and the extraorganismal apoplasm and prevents lateral diffusion (By similarity).
What are the official names of this protein?
Casparian strip membrane protein 3, VuCASP3.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Very restricted localization following a belt shape within the plasma membrane which coincides with the position of the Casparian strip membrane domain in the root endodermis.
Protein: YUKD_BACSU
Sequence: MYIDITIDLKHYNGSVFDLRLSDYHPVKKVIDIAWQAQSVSMPPREGHWIRVVNKDKVFSGECKLSDCGITNGDRLEIL
What is the function of this protein?
Required for YukE secretion.  Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss).
What are the official names of this protein?
ESX secretion system protein YukD.
What is the protein family that this protein belongs to?
Belongs to the EsaB family.
Protein: HRCA_BACAH
Sequence: MLTERQLLILQTIIDDFIGSAQPVGSRTLAKKDAITFSSATIRNEMADLEELGFIEKTHSSSGRVPSEKGYRFYVDHLLAPQNLPKDEIVQIKDLFAERIFEAEKIAQQSAQILSELTNYTAIVLGPKLSTNKLKNVQIVSLDRQTAVAIIVTDTGHVQSKTITVPESVDLSDLEKMVNILNEKLSGVPMSELHNKIFKEIVTVLRGYVHNYDSAIKMLDGTFQVPLSEKIYFGGKANMLSQPEFHDIHKVRSLLTMIDNEAEFYDILRHKQVGIQVKIGRENSATAMEDCSLISATYSIGEEQLGTIAILGPTRMQYSRVISLLQLFTRQFTDGLKK
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: Y778_MYCA1
Sequence: MARTDHDRWDLATSVGATATMVAAQRALSSDANLIDDPYAAPLVRAVGIDVYVRLVDGEIQPGTSEFDPHRMAKGMACRTRFYDDFFLDAARAGVGQAVILASGLDARAYRLPWPAGTVVYEVDMPDVIEFKTLTLADLGAQPTAQRRTVAIDLRDDWAAALREEGFDTQAPAAWSAEGLLVYLPEQAQDALFDNITALSAPGSRLAFDFVPDTAVFADPRWRAHHERMSELGFEVDFNDLVYHGERSHIVDHLSGRGWRVTSRTIAELHAANGFAYAADDVAAAFADVTYSSAVLGG
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase MAV_0778.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: PEN2A_PENVA
Sequence: MRLVVCLVFLASFALVCQGEAYRGGYTGPIPRPPPIGRPPFRPVCNACYRLSVSDARNCCIKFGSCCHLVKG
What is the function of this protein?
Antibacterial activity against M. luteus and E. coli bacteria.  Antifungal activity against N. crassa and F. oxysporum.  Presents chitin-binding activity.
What are the official names of this protein?
Penaeidin-2a, P2, Pen-2, Pen-2a.
What is the protein family that this protein belongs to?
Belongs to the penaeidin family.
What are the subcellular locations of this protein?
Cytoplasmic granule. Note=Cytoplasmic granules of hemocytes and to a lesser extent in small granules of hemocytes.
Protein: TSAD_LACJO
Sequence: MTKKDVRILAFESSCDETSTAVIKNGREIESLIVATQIKSHQRFGGVVPEVASRHHIEVITQITKEALDKANATWDDIDAIAVTYGPGLVGALLIGVSAAKAASMATGIPLIGVDHIMGHIMAAQLKDEIEYPALALQVSGGHTEIVLMKDPIHFEIVGDTRDDAAGEAYDKIGRVLGVNYPAGKTIDEWAHKGKDTFHFPRAMMEDDDYDFSFSGLKSAFINTCHHADQIHEELDKYDLAASFQASVVDVLSHKTIRAIKEYKPKTFILGGGVAANHGLRDRLAEEIEKLPADIKPKVILPDLKLCGDNAAMIGAAAYNLYQAGKFSDVNLNADPSLELPYADSMLK
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MED18_CANGA
Sequence: MVQRLSLMATIADDDFPLFKTSINILTGSPAVVYANLMVVWKPNPNYEVDNLNSKNELVEPTRMTTATSIPLELILNDPVSKNNGVDSDEILNTMKEQEFPIKQEQLFDMINNPSNNTINWTLTTADIPAAGSNRKVSMQAIQEATIVHQAGNNPTLANVMAELGYSFDYMYVTVGVRFVHKRDVIIHCHKVWDIAEDNIIQVTKGGYVVHTFVTVNRATDIERLNLAEANLLSLQRDLSGYLDFKVPDRKSMDSRTNLTQKDITL
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 18, Mediator complex subunit 18.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 18 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CPHA_SYNY3
Sequence: MKILKTLTLRGPNYWSIRRKKLIVMRLDLEDLAERPSNSIPGFYEGLIRVLPSLVEHFCSPGHRGGFLARVREGTYMGHIVEHVALELQELVGMTAGFGRTRETSTPGIYNVVYEYVDEQAGRYAGRAAVRLCRSLVDTGDYSLTELEKDLEDLRDLGANSALGPSTETIVTEADARKIPWMLLSARAMVQLGYGVHQQRIQATLSSHSGILGVELACDKEGTKTILQDAGIPVPRGTTIQYFDDLEEAINDVGGYPVVIKPLDGNHGRGITINVRHWEEAIAAYDLAAEESKSRSIIVERYYEGSDHRVLVVNGKLVAVAERIPAHVTGDGTSTITELIDKTNQDPNRGDGHANILTKIVVNKTAIDVMERQGYNLDSVLPKDEVVYLRATANLSTGGIAIDRTDDIHPENIWLMERVAKVIGLDIAGIDVVTSDISKPLRETNGVIVEVNAAPGFRMHVAPSQGLPRNVAAPVLDMLFPSGTPSRIPILAVTGTNGKTTTTRLLAHIYRQTGKTVGYTSTDAIYINEYCVEKGDNTGPQSAAVILRDPTVEVAVLETARGGILRAGLAFDTCDVGVVLNVAADHLGLGDIDTIEQMAKVKSVIAEVVDPSGYAVLNADDPLVAAMADKVKAKVAYFSMNPDNPVIQNHIRRNGIAAVYESGYVSILEGSWTLRVEEATLIPMTMGGMAPFMIANALAACLAAFVNGLDVEVIRQGVRTFTTSAEQTPGRMNLFNLGRYHALVDYAHNPAGYRAVGDFVKNWHGQRFGVVGGPGDRRDSDLIELGQIAAQVFDRIIVKEDDDKRGRSGGETADLIVKGILQENPGAAYEVILDETVALNKALDQVEEKGLVVVFPESVSKAIELIKARKPIG
What is the function of this protein?
Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
What are the official names of this protein?
Cyanophycin synthetase, Cyanophycin synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the MurCDEF family.
Protein: DEOC_NATPD
Sequence: MDRDTFAARIDHTVLGPETAPGDVEAVLDAAAEYGMNACVPPCYVEAASDYAPDVTLVSVCGFPHGQHATETKATEAETVWQAGADEIDVVINVGRLRGGDTDAVRAEIEQVVAAVPVPVKVIVEAPLLSASELRTACELAADADAAYLKTATGFNGDATVAAVETMAEYLPVKASGGIGSFEAAVEMFDAGADRIGASAGAAIVDGFDPAAFET
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMC_COXBU
Sequence: MYLKTIKLAGFKSFVDPTLIPIRGSMNAIVGPNGCGKSNVVDAVRWVIGETSAKQLRGQSMSDVIFNGTTSRKPVGKASIELHFDNSEGRIGGEYAKYGEIAIRREVERDGQSNYFINGAHVRRRDVVDVFLGTGLGPRSYAIVEQGMISNLIEAKPEELRVYIEEAAGISKYKERRRETESRMRHTQENLDRVNDIAEELAKQLRHLKRQANAAERYKAYKQEERALGAQFKVLQWKALDHKLSEHDQAINQKNTRREEKQSEQHRIETEIEKMREQLTDVNEKHNAVQKRYYGLGADIARLEQRIKDTQEKIHQWQSELEENENVWEELQNNTAECEAQITELETELEHLKPRSSDIHSAAAEASKELAQAESNMARWQEAWEAFQAETSQTMSQLEVMRTKREHCERQLTDLEKSKQQLQQNLKQLQLDQLLNEIAPLSSQSELLNAELSDSQSKLQSLAETIASRRDANQTTREELQTQRRELQALEARAASLEALQKAALGESDGKISEWLSSQQLKENPRLGQKLVVNPGWEIAVETVLSGFFDAVCVDAALPFLTDLTTVSEGRVTLVEKKSVSASAFDKAPTLASQVKSEWPFQQWLAGIYIADTLDQAKQLQSSLQENESVITKEGLWLGPHWARISKLQDAPQSGFLLREQQLKQLKANILGQQKKCDEQEALLKSGEQQLNQLETDRDTLLQTYQKLNAEATTVQSALSTKQAQLDNAQQQQTRLKIGLNECEQQIEQCQQQLTLIKNKASSLDDSQGLLATRREEMIRERDHYRTQLIELREKAHQKRKEADELEIRLASNEDQLSLLRQTVARDQRQLKQLTERREMLSQYLSEGDKPLEELNEKLQTQLEQRLILETELREVEKELEEANQLLRHLEEKRVSTQKALNEAQAQLEELRMQRQTVSVRQTTIKEQLSENDFDLEQVMAELPEEATIESWQEKLDQLVERIQRMGPINLAAIEEYESVNERKNYLDKQHADLTEALEILKNAIHKIDRETRAKFQETYDQVNQQFQSLFPRIFGGGRATLEMTDTDLLTAGVIVRAQPPGKRNVTIHMLSGGEKALTAVALVFSLFQLNPAPFCILDEVDAPLDDINVGRFCQLVKEMSKEVQFLVISHNKVTIEMADYLMGVTMQEPGVSRIVSVNMQEAIGLVEA
What is the function of this protein?
Required for chromosome condensation and partitioning.
What are the official names of this protein?
Chromosome partition protein Smc.
What is the protein family that this protein belongs to?
Belongs to the SMC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F16PA_SINMW
Sequence: MSGATLEAYLASCTTHGDELSRDVAAVIQRLAKAALDIRKLVNQGALGTVFNGMHSGSNTDGDVQKDLDILCDDQFLSCLQGAPVACYASEELENPVLLDPAARLAVAIDPLDGSSNIDNNISIGTIFSVLPAAKGPDVDPSQSFLQPGNRQLAAGFFVYGPQTALVLSLGRGTEIFIFSSRLGCFVDAYKSVGIPDRANEFAINMSNYRHWEEAIRLYVDDCLAGSEGPRERDFNMRWIASLVAEAYRILVRGGIFLYPADSRKGYSHGRIRLVYEANPIAFIVENAGGSATTSVDRILDLVPESLHQRVPLVFGSRREVARITRYHVDPNMIGERAPLFGKRGLFRA
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPB_SHISS
Sequence: MYQDKILVRQLGLQPYEPISQAMHEFTDTRDDSTLDEIWLVEHYPVFTQGQAGKAEHILMPGDIPVIQSDRGGQVTYHGPGQQVMYVLLNLKRRKLGVRELVTLLEQTVVNTLAELGIEAHPRADAPGVYVGEKKICSLGLRIRRGCSFHGLALNVNMDLSPFLRINPCGYAGMEMAKISQWKPEATTNNIAPRLLENILALLNNPDFEYITA
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COC2D_CONCL
Sequence: DVCDSLVGGRCIHNGCWCERSAPHGNCCNTSGCTARWWCPGTKFD
What is the function of this protein?
Mu-conotoxins block voltage-gated sodium channels.  This toxin reversibly blocks voltage-gated sodium channel in cephalopods, with no alteration in the voltage dependence of sodium conductance or on the kinetics of inactivation (By similarity).
What are the official names of this protein?
Mu-conotoxin-like Cal 12.1.2d, Conotoxin CalTx 12.1.3A.
What are the subcellular locations of this protein?
Secreted.