PharMolix/UniProtQA huggingface dataset:
Protein: RIBL_PYRAB
Sequence: MAGNRRIRVVVGGVFDILHVGHIHFLKMAKELGDELIVIVAHDETVKKRKGRPPINPAEDRAEVLRAIRYVDDVVIGEPGEISLELIKKLKPDVIALGPDQDFDCRTLKEKLRSIGLKVEVIRLPYLYKEDRAKTSKIIKRITEIFCD
What is the function of this protein?
Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
What are the official names of this protein?
FAD synthase, FMN adenylyltransferase, Flavin adenine dinucleotide synthase.
What is the protein family that this protein belongs to?
Belongs to the archaeal FAD synthase family.
Protein: DHSD_PIG
Sequence: MATLWRLSVLCGARGGGALVLRTSVVRPAHVSAFLQDRHTPGWCGVQHIHLSPSHQASSKAASLHWTGERVVSVLLLGLLPAAYLNPCSAMDYSLAAALTLHGHWGIGQVVTDYVRGDALQKVAKAGLLALSAFTFAGLCYFNYHDVGICKAVAMLWKL
What is the function of this protein?
Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
What are the official names of this protein?
Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial, CybS, CII-4, QPs3, Succinate dehydrogenase complex subunit D, Succinate-ubiquinone oxidoreductase cytochrome b small subunit, Succinate-ubiquinone reductase membrane anchor subunit.
What is the protein family that this protein belongs to?
Belongs to the CybS family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RSXB_ECO81
Sequence: MNAIWIAVAAVSLLALAFGAILGYASRRFAVEDDPVVEKIDEILPQSQCGQCGYPGCRPYAEAISCNGEKINRCAPGGEAVMLKIAELLNVEPQPLDGEAQELTPARMVAVIDENNCIGCTKCIQACPVDAIVGATRAMHTVMSDLCTGCNLCVDPCPTHCISLQPVAETPDSWKWDLNTIPVRIIPVEHHA
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit B, Rsx electron transport complex subunit B.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: RPIA_CHLFF
Sequence: MKEDPYLDVKKRLAREAAALVTSGMLVGLGSGSTSREFIKAIAERLAKENLDICAVASSQESYSLASSLGIPLIDDENFTSVDLVVDGADEIDPQLRMIKGGGGAIFREKILLQSSQRRLILADESKSVKVLGKFGLPVEISPYGRSSIIAALEAIGYLGNLRKNSRGGFFITNNGNYIYDIHTPNIYPHPEEDLLKLLQIHGIIEVGFVIANVEVWFGYTNGQICKENTGIV
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: AMT15_ARATH
Sequence: MSGAITCSAADLSALLGPNATAAADYICGQLGSVNNKFTDAAYAIDNTYLLFSAYLVFAMQLGFAMLCAGSVRAKNTMNIMLTNVLDAAAGGLFYYLFGYAFAFGESSDGFIGRHNFGLQNFPTLTSDYSFFLYQWAFAIAAAGITSGSIAERTKFVAYLIYSSFLTGFVYPVVSHWFWSPDGWASPFRSEDRLFGTGAIDFAGSGVVHMVGGIAGLWGALIEGPRIGRFPDGGHAIALRGHSASLVVLGTFLLWFGWYGFNPGSFTKILIPYNSGSNYGQWSGIGRTAVTTTLSGCTAALTTLFGKRLLSGHWNVTDVCNGLLGGFAAITAGCSVVDPWAAIVCGFVASLVLIGCNKLAELLKYDDPLEAAQLHGGCGAWGLIFVGLFAKEKYINEVYGASPGRHYGLFMGGGGKLLGAQLVQIIVIVGWVSATMGTLFFILKKLNLLRISEQHEMRGMDLAGHGGFAYIYHDNDDDSIGVPGSPVPRAPNPPAV
What is the function of this protein?
Involved in ammonium transport.
What are the official names of this protein?
Putative ammonium transporter 1 member 5, AtAMT1;5.
What is the protein family that this protein belongs to?
Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DEOD_STRTR
Sequence: DPLRAKFIAENFLEDAVCFNEVRNMFGYTGTYKGERISVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNENVHVRELVLAQAAATNSNIIRNDWPQYDFPQIASFNLLDKAYHIAKNFGMTTHVGNVLSSDEKYSNYFEKNIELGKWGVKAVEMEAAALYYLAAQHQVDALAIMTISDSLVNPDEDTTAEERQNTFTDMMKVGLETLIAD
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: JZT55_CHIGU
Sequence: MRFHTLLFLSFLLLVSCALICTAQHPGLEKSGMFHENVGKGQHIEEKRSCIERMQTCGVEAGLPCCSGAPCICPYIGDCICIQ
What is the function of this protein?
Probable ion channel inhibitor.
What are the official names of this protein?
U25-theraphotoxin-Cg1b, U25-TRTX-Cg1b, Jingzhaotoxin-55, JZTX-55.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 07 (Beta/delta-agtx) family. 03 (aga-4) subfamily. JZTX sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LIS1_YEAS8
Sequence: MTNWQQQLPLTDTQKNELDKSVLRYLNWNYKQTVRHEHAQDYESVRHAIVTLSGFLLQESVDRQEFISNNDTSNESMVDIDELLLPKKWNSIVRLQKKIIELEQNTETLVSQIKDLNTQVSELAQFKPTTSNGTSAHNVLKWIPRNLPSCLINVESSVTSVKLHPNLPIVFVATDHGKLYAFDLFNYTIPLASLQSHTKAITSMDVLFTNFTNSSKKNYLVVVTASKDLQIHVFKWVSEECKFQQIRSLLGHEHIVSAVKIWQKNNDVHIASCSRDQTVKIWDFHNGWSLKTFQPHSQWVRSIDVLGDYIISGSHDTTLRLTHWPSGNGLSVGTGHEFPIEKVKFIHFIEDSPEIRFRTPSTDRYKNWGMQYCVSASRDRTIKIWEIPLPTLMAHRAPIPNPTDSNFRCVLTFKGHLSWVRDISIRGQYLFSCADDKSVRCWDLNTGQCLHVWEKLHTGFVNCLDLDVDFDSNVTPRQMMVTGGLDCKSNVFMR
What is the function of this protein?
Positively regulates the activity of the minus-end directed microtubule motor protein dynein.  Plays a central role in positioning the mitotic spindle at the bud neck during cell division.  Targets cytoplasmic dynein to microtubule plus ends, thereby promoting dynein-mediated microtubule sliding along the bud cortex and consequently the movement of the mitotic spindle to the bud neck.
What are the official names of this protein?
Nuclear distribution protein PAC1, Lissencephaly-1 homolog, LIS-1, nudF homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LIS1/nudF family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes to the plus ends of microtubules and the mitotic spindle poles.
Protein: RL23_BREBN
Sequence: MKSLHDVLKRPVITERTTDMMAEKKYVFEVPLKANKTEIKQAVEKVFGVKVEAVNTVRVPAKPKRYGKYSGYTSEWKKAIVKLTDDSKELAFYEGV
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: NUON_BEUC1
Sequence: MNFVQPVIQWASLAPILIVLGAAVLGVLIEAFAPRRVRRPVQVTLALLAAAGAFGAIAWRWAEVIGGGGGAPSTVVVGQLVEDGPALAAQGIIAILAFVGILVIAERGRRGAPGSEDAFAPQGASVPGSDYEDRARRAGLVQTEVYPLVLFSVGGMLVFPAAGDLLTLFIALEVLSLPLYLLSGLARRRRLLSQEASMKYFLLGAFSSALLLFGIALLYGYSGSVAIGEIHAATQATTGMDGLLVVGLVLLISGLLFKVGAVPFHAWTPDVYQGAPTPITGFMAACTKVAAFGALLRVVYVVAPAMTWDIQPFLWVVAVLTMVVGTVLAIVQTDMKRTLAYSSVAHAGFLLVGVVAMSPEGISSVFFYLLAYGLATIGAFALVALVRERDAEGNVTAEASHLAQWAGLGRRSPVVATVFALYLLSFAGIPLTSGFVGKFVAFAAAIDGGAWPLVVVGVLASAAAAFFYVRIIVLMFFTSPAEEAGAPSTTVVRSQGFTAVAVALTAAATLVLGVWPTPVLDLLAQATKFVV
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYFB_HAHCH
Sequence: MKFSEYWLREWVDPQLSSEALVQQITMAGLEVDAAERVAKPFSGIVVGEVLSVEPHPDADKLRVCKVSDGQEEFQVVCGAPNVAAGMKVPFAKIGAVLSGDFKIKKAKLRGVESQGMLCSEEELTLAEKSDGLMPLAADAPVGVDVRSYLKLDDNIIDVDLTPNRSDCLSILGMAREVAALNKIPFEAPEVKKTAAVIDDVFPVRVEAPEACPRYVGRVIKGVDLSAPTPQWMVEKLRRSGIRSIDAVVDVTNFVMIELGQPMHAFDLNELADGIVVRMPTPGEKLVLLDGQEITINPDTLVIADNEKPLALAGVMGGEHSGVSEKTKDIFLESAFFAPLHLAGKARSYGLHTDSSHRFERGVDYAHQARAIERATELLLEIVGGQPGPVTEICSKEHLPAKALVNLRHARVDELLGVHLDRTRVEEMLARLGLGVHKVAKDGWTFSAPTHRFDISIEVDLIEEVARLYGYNKLPVTEPMAPLGIKPLPESKVSLRRLKLHLVSRGYQEAITYTFVDQKVLSLLTPEEDTITLANPIASDMAAMRTTLWAGLLQTALYNQNRQQNRIRLFESGLRFLKRGGQIQQDPMLAGLIMGASMPEGWESKKRTVDFYDVKGDLESLLEIPGCNLSFRSAQHPALHPGQTAEVLKDGQPIGVLGALHPRIAKTLNLNGPLYLFELCLNSIADGQVPSFKGVSRFPEIRRDLAIVIDEQTPYADVALAIAQSAGEWRVHHELFDVYHGESVGADKKSLAISIVWRHPERTLRDEEITEAFDNVVKELGNRFGASLRS
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y6051_PSEF5
Sequence: MSIRDWPAAERPRERLLEQGAISLSDAELLAIFLRTGVAGKSAVDLARHLLRRFGSLRRLLEADQLTFTRQLGLGPAKYALLQAVLEMARRHLAEKLHRQSALENPLVVRDYLKSMLRHEPHEVFGCLFLDTRHRVLTFEVLFQGSIDSTTVYPRQVIKRALAHNAAAVILCHNHPSGICEPSPADRVVTRRLQEALELIDVRVLDHFIVGEGDPLSMAEYGWI
What are the official names of this protein?
UPF0758 protein PFL_6051.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: MET16_XENLA
Sequence: MALNKSMHPRNRYKDKPPDFAYLASKYPEFKQHVNVNLAGRVSLNFKDPCAVRALTCTLLKEDFGLTIDIPLERLIPTVPLRLNYIHWVEDLINYHDSDKTALRRGIDIGTGASCIYPLLGATLNGWYFLATEVDDICYNYAKKNVEQNNLSDLIKVVKVPQKTLLMDALKEESEIIYDFCMCNPPFFANQLEAQGVNSRNPHRSPPSSVNTGGITEIMAEGGELEFVKRIIHDSLKLKKRLRWYSCMLGKKCSLAPLKEELRLQGVPKVAHTEFYQGRTMRWALAWSFYEEVIIPNPPKKRKLEKPRKPMVFTVLESVIKLLTEKLPSGSEVPESITLVADCIKKILTDLKVQHKIVPCGRDEESLFLTAVENSWIHIRRKKRDRTRQLRELPRAPNDFLQSNKPDALHKETSDQGQNSGDPPATKESESVTQSETCVPHTSSTPESAAPALSEPMEAENSDSKPDEVCNNDEEQDLGEDMKQSCGEASSAPQGSGSPFLFKCVLNVKKENSDVLVEMHCVEGQNRDLMNQLCTYIRNQIYRLATS
What is the function of this protein?
RNA N6-methyltransferase that methylates adenosine residues at the N(6) position of a subset of RNAs and is involved in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts.  Able to N6-methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs).  In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure.  Plays a key role in S-adenosyl-L-methionine homeostasis by mediating N6-methylation of MAT2A mRNAs, altering splicing of MAT2A transcripts: in presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifically N6-methylates the first hairpin of MAT2A mRNA, impairing MAT2A splicing and protein expression.  In S-adenosyl-L-methionine-limiting conditions, binds the 3'-UTR region of MAT2A mRNA but stalls due to the lack of a methyl donor, preventing N6-methylation and promoting expression of MAT2A.  In addition to mRNAs, also able to mediate N6-methylation of U6 small nuclear RNA (U6 snRNA): specifically N6-methylates adenine in position 43 of U6 snRNAs.
What are the official names of this protein?
RNA N6-adenosine-methyltransferase mettl16, Methyltransferase 10 domain-containing protein, Methyltransferase-like protein 16, N6-adenosine-methyltransferase METTL16, U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL16/RlmF family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: CA1A_CONVE
Sequence: GGCCSYPPCAVSNPQHC
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.
What are the official names of this protein?
Alpha-conotoxin-like Vn, Vn1A.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CH10_STAAT
Sequence: MLKPIGNRVIIEKKEQEQTTKSGIVLTDSAKEKSNEGVIVAVGTGRLLNDGTRVTPEVKEGDRVVFQQYAGTEVKRDNETYLVLNEEDILAVIE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_MAIZE
Sequence: MVREEITGSTQTLEWKCVESRVDSKRLYYGRFILSPLRKGQADTVGIALRRALLGEIEGTCITRAKFGNVPHEYSTIVGIEESIQEILLNLKEIVLRSNLYGVRDASICVKGPRYITAQDIILPPSVEIVDTTQPIANLREPVDFCIELQIKRDRAYHTELRKNSQDGSYPIDAVFMPVRNVNYSIFSCGNGNEKHEILFLEIWTNGSLTPKEALYEASRNLIDLFLPFLHTEEEGTSFEENKNRLTPPLLTFQKRFTNLKKNKKGIPLNCIFIDQLELPSRTYNCLKRANIHTLLDLLSKTEEDLMQINSFRMEDGKLIWDTLEKHLPIDLPKNKFSL
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CYSN_COLP3
Sequence: MSHQSDLIEEDIQAYLKQHENKELVRFLTCGSVDDGKSTLIGRLLHDSKMIFEDQLAAIEKDSKKSGTTGEAIDLALLVDGLQSEREQGITIDVAYRYFSTDKRKFIIADTPGHEQYTRNMATGASTCDIAIILIDARYGVQTQTRRHSFICSLLGIKHIVVAVNKMDLVDYSQERYQEIKKEYREFTESLEFSDVRFVPLSALNGDNVVDESVNMPWYPGATLMKLLNTIDVKTQEQFTQLRFQVQYVNRPNLDFRGFAGTLASGHVLVGDTIVALPSGKESVVKEIVTYDGNLERADKGMAVTLTLEDEIDISRGEIIVKKGSLPISAKEFSATVVWMHENELEPGREYFIKHGSKMTTGHAQNIVSKYDVNTMESLSSSQLAINDIGIVNFVAGETLHFDAYEDNQGTGAFIIIDRLSNVTVGAGMINHAIDEKAQEYSAFELELNALVRKQFPHWGARDITK
What is the function of this protein?
With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 1, ATP-sulfurylase large subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
Protein: RPPH_YERPB
Sequence: MIDDDGYRPNVGIVICNRQGEVLWARRYGQHSWQFPQGGINPGETPEQAMYRELFEEVGLNKKDVRILASTRNWLRYKLPKRLVRWDTKPVCIGQKQRWFLLQLMCNEAEINMQRSSTPEFDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFAATVMPVQEVAPPRVPPAYRRKRG
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: NU6M_ANOQU
Sequence: MTKLIIMTICLIISFIFMQMKHPLSMGLMLLTQTFLTCLLTGIYVKTFWFSYVLFLIFLGGMLILFIYVHSLSSNEMFTMSFNLTTLSLLIFFLMTLFFFIIDKSLIEQFISNMEMEMFSFNNNLINENILFLNKMYNFPTNLITLLLINYLFLTLLVTVKITKKFYGPLRPMN
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: DUT_CWPXG
Sequence: MFNMNINSPVRFVKETNRAKSPTRQSPGAAGYDLYSAYDYTIPPGERQLIKTDISMSMPKFCYGRIAPRSGLSLKGIDIGGGVIDEDYRGNIGVILINNGKCTFNVNTGDRIAQLIYQRIYYPELEEVQSLDSTDRGAQGFGSTGLR
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: PDE1_CAEEL
Sequence: MNRARKTSSCGCFRSAFCLLKPSTSSASEEHGDSDKKLLSVQLITPRDEEEQTSSRSIKIPPLDLNGLDCKKNAVAARRAGRRRTSEGGGVRGKGHFAEVVLDGLQRPVSLLRNQKEKSNSDDNCQEKEPTSPSSSRKKSYDNAPALESLEKLRYILHQLNSGQLPLEDLKRNIEYAALVLETAYMDETRRICDEDDDLAEVTPETVPDEVREWLAATFTRQNAGKKRDKPKFKSVANAIRTGIFFEKLFRKQQVVQCPIPPEIAELMKEVCTWSFSPFQLNEVSEGHALKYVGFELFNRYGFMDRFKVPLTALENYLSALEVGYSKHNNPYHNVVHAADVTQSSHFMLSQTGLANSLGDLELLAVLFGALIHDYEHTGHTNNFHIQSQSQFAMLYNDRSVLENHHVSSCFRLMKEDDKNILTHLTRDEYKELRNMVIEIVLATDMSTHFMQIKTMKSMLSLPEGIDKNKALCLIVHACDISHPAKPWNLHERWTEGVLEEFFRQGDLEASMGLPYSPLCDRHTVHVADSQIGFIDFIVEPTMVVCGELLVKMVEPLVSLPPTDSLFPPSVDGGDDKSPSNALSPLPDLRNSSTSPSSIRRIPLNYAGKLDIPTPWMKFLHENKAHWKERAAKEEEERKIKEAAEAEAAAKQVEENKENGVTTN
What is the function of this protein?
Redundantly with pde-5, plays a role in the AFD thermosensory neurons to regulate microvilli receptive ending morphology, possibly by regulating cGMP levels.
What are the official names of this protein?
Probable 3',5'-cyclic phosphodiesterase pde-1.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase family.
Protein: SBE22_YEAS7
Sequence: MTSIQERGTSAHLHSLKEGEASDRSSEMLPKQRSIIGSHVQRPPSQTTLGRSRAGSNTMNKVSGLDIARRPSENLLSNMNCSDNGNGGNMLNSFVNSALPPPKVNPAQTRRERPASNSSIGTKTTEVFSSTSASSSLGDTSDEGEGSDADKSKINTFPSILMEKATQGRGANGNGMRSASNNTIVEATTDGSKMALQKSMSFDDTAAEKTMNKSRHSYQEQFSSKKSQSSLLNSKQRSRAKSQTCSSTGYNNSSILKTFGISSKISNSSDRIEASSLEFNVPSQKPLNCKPLTPSQKYRLRKEQSEMNLRNTIKRKEKFYDSQEQILELQEGDVDDSLIWNVPMASLSTNSFLASAKPDDMNNLAGKNDLSEYTGGLVNDNSEISYTKQNHRYSNISFASTTSNASLLDFNEMPTSPIPGLNKVTDFQFIQDTTKSLASVYLHSSNRLSRSKLSERTKSSDFLPIELKEAQNQGMEDLILVSENKLDVVSHSRPSWLPPKDRQEKKLHERQINKSMSVASLDQLGKNKDREEKLIRDETNRQKYVLLLDRDITRNSSLQSLSKMVWDTPFSDETRSTIYSEILQSKTRFITKNYIQPFHELQELLTKMGDFPKNKEIEISQLIETSLRRKVSGLHDICPDLMLLLKIKSISSQGIVTGDELLFHHFLVSESFQNLGLNEIWNIVNLVQMTCFNDLCKEKFDAKVLERKGVVAGYLSQNEEFKDEFNTECINSTTWWNILERIDHKLFMWIMDIIVVNNSQSYKNSPINEDEFVNKDWEYYRSKKVVINYKILISFALNVLLNYHFGFTDLRSLCNVNDQRFCIPVFINDEFVDADTVNAVFIKKWAHYYKKF
What is the function of this protein?
With SBE2, is involved in cell wall integrity and polarity processes like bud growth, through the transport of CHS3 and UTR2 to sites of growth.
What are the official names of this protein?
Protein SBE22.
What is the protein family that this protein belongs to?
Belongs to the SBE2 family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus.
Protein: CCL5_HUMLU
Sequence: MENSSKAIVDERSGYCKSNSIFYSKREPVQLPQNHSVDVTTFISSRAHHGKIAFIDAATGRHLTFPQLWRAVDSVATCLSAMGIRKGDVILLLSPNSIYFPVVCLAVMSLGAIITTTNPLNTPREIAKQITDSKPVLAFTIPQLVSKIAGSNLPIVIIDDEVKSSLEKTLNIVSSLGEMMRKEPSPNRIGYRVNQEDTATLLYSSGTTGASKGVVSSHKNLIAMVQTILSRFGTEDGEHTFICTVPMFHIYGLAAFAMGLLSSGSTIVILSKFEIHEMLSAIEKYRATYLPLVPPILMALLKNANHIRAKYDLSSLQSVLSGGAPLSKEVIEGFVENYPTVSILQGYGLTESTGIGASTDCLQESRRYGTAGMLSPSMEAKIVNPETGEALSVNRTGELWLRGPTIMKGYFSNEEATSSTIDSEGWLRTGDLCYIDEDGFIFVVDRLKELIKYKGYQVAPAELEALLLSHPEISDAAVIPYPDKEAGQFPMAYVVRKGGSNLSESTVMDFIAKLVAPYKRIRKVAFVASIPKNPSGKILRKDLIKLATSKL
What are the official names of this protein?
Probable CoA ligase CCL5, HlCCL5.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: TATA_RHOPS
Sequence: MGSLSIWHWIVVIAVVLLLFGRGKISDLMGDVAQGIKSFKKGLQDDEKTAEKPDPVKSIDHNAPTAAAPTRTDVGSKAV
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: LEU1_POLAQ
Sequence: MSDKVIIFDTTLRDGEQSPGASMTKDEKVRIARQLERLKVDVIEAGFAASSEGDFQAISAVAAAVKDSIVCSLARANDKDITRAADALQAANAKRIHAFLATSPLHMAVKLRMSPEEVLEQAKRSIRFARNLASDIEFSAEDGYRSEMDFLCRVVEAVINEGASTINIPDTVGYATPELYGDFIKTLRTRVPNSDKAVWSVHCHNDLGMAVANSLAGVKIGGARQIECTINGLGERAGNTALEEIVMALRTRKDYFDMVCGIDASQIVPASKLVSQITGFVVQPNKAVVGANAFAHTSGIHQDGILKNRDTYEIMRAEDVGWSANKIVLGKLSGRNAFKQRLQELGITVEAEADLNEAFTRFKALADQKSEIFDEDIIAIMSDSAAAEEGEHYHFISLSQHSETGERPKSRVIFRMGDKEVSSEAEGNGPVDASLNAIEEIAKSGAEQLLYSVNAITSGTQSQGEVTVRLSKGGRIVNGVGTDPDIIAASAKAYLSALNKLHDPSQAKLNAQMAP
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: HSCA_BURTA
Sequence: MALLQISEPGMAPAPHQRRLAVGIDLGTTNSLVAAVRNSIPEALPDDTGRVLLPSVVRYLEKGGRRIGHAAKEEAAIDPRNTIVSVKRFMGRGKAEVEGAANAPYEFVDAPGMVQIRTVDGVKSPVEVSAEILATLRQRAEDTLGDDLVGAVITVPAYFDDAQRQATKDAARLAGLNVLRLLNEPTAAAIAYGLDNGAEGLYAVYDLGGGTFDLSILKLTKGVFEVLAAGGDSALGGDDFDHLLFAHVLVQAGLDAAALAPEDVRLLLDRVRGVKEALSAAQQAQLDVKLSTGEKLVQTITRDTFAALVEPLVQRTLAPTRKALRDARVSAADIKGVVLVGGATRMPVIRDAVEKYFGQPPLVNLDPDQVVALGAAIQADLLAGNRSGGDDWLLLDVIPLSLGVETMGGLVEKIIPRNSTIPVARAQEFTTFKDGQTAMAIHVVQGERELVSDCRSLARFELRGIPPMAAGAARIRVTYQVDADGLLSVFAREQHSGVEASVVVKPSYGLGDDDIARMLEDSFKTAEVDMRARALREAQVEAQRLVEATEAALAADGDLLDASERATVEALVASLRALAPGDDANAIDAATKALAEGTDEFAARRMNKSIKRALAGRKLDEI
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: PROF1_HORVU
Sequence: MSWQTYVDDHLCCEIDGQHLTSAAILGHDGRVWVQSPNFPQFKPEEIAGIIKDFDEPGHLAPTGLFLGGTKYMVIQGEPGVVIRGKKGTGGITIKKTGMPLILGIYDEPMTPGQCNLVVERLGDYLVEQGF
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG.
What are the official names of this protein?
Profilin-1.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.