PharMolix/UniProtQA huggingface dataset:
Protein: TFE_METMJ
Sequence: MVSVTELLDDPAINAYILRMIGEEGIELLRRFPEGGEHSDEELAEMTGVNLNTVRHTLYTLYERRLAEYRRLKNTETGWLTYLWHLRLDRVHDVLEEQVRDALEHLDARLAYEEKNDFYMCRNCSVVYTFTDAANWNFECPNCEEMLEHFDNELIAVALRKRIDRIKESLGSA
What is the function of this protein?
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase.  Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment.  Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal.  It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes.  Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
What are the official names of this protein?
Transcription factor E, TFE, TFIIE subunit alpha homolog, Transcription initiation factor TFIIE.
What is the protein family that this protein belongs to?
Belongs to the TFE family.
Protein: O51E2_MOUSE
Sequence: MSSCNFTHATFLLIGIPGLEEAHFWFGFPLLSMYAVALFGNCIVVFIVRTERSLHAPMYLFLCMLAAIDLALSTSTMPKILALFWFDSREITFDACLAQMFFIHTLSAIESTILLAMAFDRYVAICHPLRHAAVLNNTVTVQIGMVALVRGSLFFFPLPLLIKRLAFCHSNVLSHSYCVHQDVMKLAYTDTLPNVVYGLTAILLVMGVDVMFISLSYFLIIRTVLQLPSKSERAKAFGTCVSHISVVLAFYVPLIGLSVVHRFGNSLDPIVHVLMGDVYLLLPPVINPIIYGAKTKQIRTRVLAMFKISCDKDIEAGGNT
What is the function of this protein?
Olfactory receptor.  The activity of this receptor is probably mediated by G-proteins wich induce elevation of intracellular Ca(2+), cAMP and activation of phosphorylation of the protein kinases PKA and MAPK3/MAPK1.  Activation of OR51E2 may affect melanocyte proliferation, differentiation, and melanogenesis and may increase proliferation and migration of primary retinal pigment epithelial (RPE) cells (By similarity).  Activated by the short chain fatty acids (SCFA), acetate and propionate (PubMed:23401498).  In response to SCFA, may positively regulate renin secretion and increase blood pressure (PubMed:23401498).  May also be activated by steroid hormones and regulate cell proliferation (By similarity).  Activated by L-lactate in glomus cells (PubMed:26560302, PubMed:30258151).
What are the official names of this protein?
Olfactory receptor 51E2, Olfactory receptor 78.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
Protein: RREB1_HUMAN
Sequence: MTSSSPAGLEGSDLSSINTMMSAVMSVGKVTENGGSPQGIKSPSKPPGPNRIGRRNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPPSPLKRRRLSSKRKLSHDAESEREDPAPAKKMVEDGQSGDLEKKADEVFHCPVCFKEFVCKYGLETHMETHSDNPLRCDICCVTFRTHRGLLRHNALVHKQLPRDAMGRPFIQNNPSIPAGFHDLGFTDFSCRKFPRISQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATPLPGDALDQKGFLALLGLQHTKDVRPAPAEEPLPDDNQAIQLQTLKCQLPQDPGCTNLLSLSPFEAASLGGSLTVLPATKDSIKHLSLQPFQKGFIIQPDSSIVVKPISGESAIELADIQQILKMAASAPPQISLPPFSKAPAAPLQAIFKHMPPLKPKPLVTPRTVVATSTPPPLINAQQASPGCISPSLPPPPLKLLKGSVEAASNAHLLQSKSGTQPHAATRLSLQQPRAELPGQPEMKTQLEQDSIIEALLPLSMEAKIKQEITEGELKAFMTAPGGKKTPAMRKVLYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSSAAELVDAFCAPDTVCRLCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHLHVPEQDIESYVLAADGLGPAEAPAAEASGRGEDSGCAALGDCKPLTAFLEPQNGFLHRGPTQPPPPHVSIKLEPASSFAVDFNEPLDFSQKGLALVQVKQENISFLSPSSLVPYDCSMEPIDLSIPKNFRKGDKDLATPSEAKKPEEEAGSSEQPSPCPAPGPSLPVTLGPSGILESPMAPAPAATPEPPAQPLQGPVQLAVPIYSSALVSSPPLVGSSALLSGTALLRPLRPKPPLLLPKPPVTEELPPLASIAQIISSVSSAPTLLKTKVADPGPASTGSNTTASDSLGGSVPKAATTATPAATTSPKESSEPPAPASSPEAASPTEQGPAGTSKKRGRKRGMRSRPRANSGGVDLDSSGEFASIEKMLATTDTNKFSPFLQTAEDNTQDEVAGAPADHHGPSDEEQGSPPEDKLLRAKRNSYTNCLQKITCPHCPRVFPWASSLQRHMLTHTDSQSDAETAAAAGEVLDLTSRDREQPSEGATELRQVAGDAPVEQATAETASPVHREEHGRGESHEPEEEHGTEESTGDADGAEEDASSNQSLDLDFATKLMDFKLAEGDGEAGAGGAASQEQKLACDTCGKSFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPAEKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQKARHAKHHGKDSDKEERGEEDSENESTHSGNNAVSENEAELAPNASNHMAVTRSRKEGLASATKDCSHREEKVTAGWPSEPGQGDLNPESPAALGQDLLEPRSKRPAHPILATADGASQLVGME
What is the function of this protein?
Transcription factor that binds specifically to the RAS-responsive elements (RRE) of gene promoters (PubMed:9305772, PubMed:15067362, PubMed:8816445, PubMed:10390538, PubMed:17550981).  Represses the angiotensinogen gene (PubMed:15067362).  Negatively regulates the transcriptional activity of AR (PubMed:17550981).  Potentiates the transcriptional activity of NEUROD1 (PubMed:12482979).  Promotes brown adipocyte differentiation (By similarity).  May be involved in Ras/Raf-mediated cell differentiation by enhancing calcitonin expression (PubMed:8816445).
What are the official names of this protein?
Ras-responsive element-binding protein 1, RREB-1, Finger protein in nuclear bodies, Raf-responsive zinc finger protein LZ321, Zinc finger motif enhancer-binding protein 1, Zep-1.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus speckle.
Protein: NCAP_SENDO
Sequence: MAGLLSTFDTFSSRRSESINKSGGGAVIPGQRSTVSVFVLGPSVTDDADKLSIATTFLAHSLDTDKQHSQRGGFLVSLLAMAYSSPELYLTTNGVNADVKYVIYNIEKDPKRTKTDGFIVKTRDMEYERTTEWLFGPMVNKSPLFQGQRDAADPDTLLQIYGYPACLGAIIVQVWIVLVKAITSSAGLRKGFFNRLEAFRQDGTVKGALVFTGETVEGIGSVMRSQQSLVSLMVETLVTMNTARSDLTTLEKNIQIVGNYIRDAGLASFMNTIKYGVETKMAALTLSNLRPDINKLRSLIDTYLSKGPRAPFICILKDPVHGEFAPGNYPALWSYAMGVAVVQNKAMQQYVTGRTYLDMEMFLLGQAVAKDAESKISSALEDELGVTDTAKERLRHHLANLSGGDGAYHKPTGGGAIEVALDNADIDLEPEAHTDQDARGWGGDSGDRWARSMGSGHFITLHGAERLEEETNDEDVSDIERRIARRLAERRQEDATTHEDEGRNNGVDHDEEDDAAAAAGMGGI
What is the function of this protein?
Encapsidates the genome in a ratio of one N per six ribonucleotides, protecting it from nucleases.  The nucleocapsid (NC) has a helical structure with 13. 07 N per turn.  The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication.  Replication is dependent on intracellular concentration of newly synthesized N, termed N(0), which corresponds to the protein not associated with RNA.  In contrast, when associated with RNA, it is termed N.  During replication, encapsidation by N(0) is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, NP, Protein N.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses nucleocapsid family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: GPPA_SALG2
Sequence: MNSTSLYAAIDLGSNSFHMLVVREAAGSIQTLTRIKRKVRLAAGLNNDNHLSAEAMERGWQCLRLFAERLQDIPQPQIRVVATATLRLAVNAGEFIAKAQTILGCPVQVISGEEEARLIYQGVAHTTGGADQRLVVDIGGASTELVTGTGAQTTSLFSLSMGCVTWLERYFSDRNLAQENFDDAEKVARDVLRPVADELRFHGWKVCVGASGTVQALQEIMMAQGMDERITLAKLQQLKQRAIQCGRLEELEIEGLTLERALVFPSGLAILIAIFTELNIQSMTLAGGALREGLVYGMLHLAVDQDIRSRTLRNIQRRFIVDTDQANRVAKLADNFLKQVENAWHIEPISRELLLSACQLHEIGLSVDFKQAPYHAAYLVRHLDLPGYTPAQKKLLATLLLNQTNPVDLSSLHQQNAVPPRVAEQLCRLLRLAILFAGRRRDDLVPEITLQALNENLTLTLPGDWLAHHPLGKELIDQESQWQSYVHWPLDVR
What is the function of this protein?
Catalyzes the conversion of pppGpp to ppGpp.  Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.
What are the official names of this protein?
Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase, Guanosine pentaphosphate phosphohydrolase, pppGpp-5'-phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the GppA/Ppx family. GppA subfamily.
Protein: OPUBA_BACSU
Sequence: MLTLENVSKTYKGGKKAVNNVNLKIAKGEFICFIGPSGCGKTTTMKMINRLIEPSAGKIFIDGENIMDQDPVELRRKIGYVIQQIGLFPHMTIQQNISLVPKLLKWPEQQRKERARELLKLVDMGPEYVDRYPHELSGGQQQRIGVLRALAAEPPLILMDEPFGALDPITRDSLQEEFKKLQKTLHKTIVFVTHDMDEAIKLADRIVILKAGEIVQVGTPDDILRNPADEFVEEFIGKERLIQSSSPDVERVDQIMNTQPVTITADKTLSEAIQLMRQERVDSLLVVNDERVLQGYVDVEIIDQCRKKANLVSEVLHEDIYTVLGGTLLRDTVRKILKRGVKYVPVVDEDRRLIGIVTRASLVDIVYDSLWGEEKQLAALS
What is the function of this protein?
Involved in a high affinity multicomponent binding-protein-dependent transport system for choline.  Probably responsible for energy coupling to the transport system.
What are the official names of this protein?
Choline transport ATP-binding protein OpuBA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: SBMC_PECCP
Sequence: MSIRIELAESMEVLSLRVVGPYYEKIPQGFDEILSWAREHHLSIDKSLAFYWDDPSKVEADELRADVAITCKEMPSTLPEDVGIRREVIPGGLYAVTHTIVENGDFAKAWDDFYKAINAQGYCPAGDICYESYLCDGSNGKWDIEIWQSVEAAN
What is the function of this protein?
Inhibits the supercoiling activity of DNA gyrase.  Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase.  It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell.
What are the official names of this protein?
DNA gyrase inhibitor.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BTUC_SALCH
Sequence: MLTFARQQQRRNVRWLLSLSLLVLLATLLSLCAGEQWIAPGDWLSARGELFVWQIRLPRTLAVLLVGAALALSGAVMQALFENPLTEPGLLGVSNGAGVGLIAAVLLGQGQLPGWALGLCAIAGALIITLILLRFARRHLSTSRLLLAGVALGIICSALMTWAIYFSTSFDLRQLMYWMMGGFGGVDWQQSWLMIALIPVLIWICCQSQPLNMLALGETSARQLGLPLWFWRNLLVIATGWMVGVSVAMAGAIGFIGLVIPHILRLCGLTDHRVLLPGCALAGAIALLLADVVARLALASAELPIGVVTATLGAPVFIWLLLKSAR
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Involved in the translocation of the substrate across the membrane.
What are the official names of this protein?
Vitamin B12 import system permease protein BtuC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: 3S14_OXYMI
Sequence: MKTLLLTLVVVTIVCLDLGYTMTCYNQQSSEAKTTTTCSGGVSSCYKETWYDGRGTRIERGCGCPRAKKGIERICCGTDKCNN
What is the function of this protein?
Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.
What are the official names of this protein?
Short neurotoxin 3FTx-Oxy4.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type I alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MURD_NEIM0
Sequence: MTFQNKKILVAGLGGTGISMIAYLRKNGVEVAAYDAELKPERVAQIGKMFDGLVFYTGRLKDALDNGFDILALSPGISERQPDIEAFKQNGGRVLGDIELLADIVNRRGDKVIAITGSNGKTTVTSLVGYLCIKCGLDTVIAGNIGTPVLEAEWQREGKKADVWVLELSSFQLENTESLRPTAATVLNISEDHLDRYDDLLDYAHTKDKIFRGDGVQVLNADDAFCRAMKRAGREVKWFSLEYEADFWLERETGRLKQGNEDLIATQDIPLQGLHNATNVMAAVALCEAVGLPREALLEHVKTFQGLPHRVEKIGEKNGVVFIDDSKGTNVGATAAAIAGLQNPLFVILGGMGKGQDFTPLRDALAGKAKGVFLIGVDALQIRRDLDGCDLNMTDCATLEEAVQKAYAQAEAGDIVLLSPACASFDMFKGYAHRSEVFIGAFKAL
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZCH14_HUMAN
Sequence: MASNHPAFSFHQKQVLRQELTQIQSSLNGGGGHGGKGAPGPGGALPTCPACHKITPRTEAPVSSVSNSLENALHTSAHSTEESLPKRPLGKHSKVSVEKIDLKGLSHTKNDRNVECSFEVLWSDSSITSVTKSSSEVTEFISKLCQLYPEENLEKLIPCLAGPDAFYVERNHVDLDSGLRYLASLPSHVLKNDHVRRFLSTSSPPQQLQSPSPGNPSLSKVGTVMGVSGRPVCGVAGIPSSQSGAQHHGQHPAGSAAPLPHCSHAGSAGSALAYRTQMDTSPAILMPSSLQTPQTQEQNGILDWLRKLRLHKYYPVFKQLSMEKFLSLTEEDLNKFESLTMGAKKKLKTQLELEKEKSERRCLNPSAPPLVTSSGVARVPPTSHVGPVQSGRGSHAAELRVEVEQPHHQLPREGSSSEYSSSSSSPMGVQAREESSDSAEENDRRVEIHLESSDKEKPVMLLNHFTSSSARPTAQVLPVQNEASSNPSGHHPLPPQMLSAASHITPIRMLNSVHKPERGSADMKLLSSSVHSLLSLEERNKGSGPRSSMKVDKSFGSAMMDVLPASAPHQPVQVLSGLSESSSMSPTVSFGPRTKVVHASTLDRVLKTAQQPALVVETSTAATGTPSTVLHAARPPIKLLLSSSVPADSAISGQTSCPNNVQISVPPAIINPRTALYTANTKVAFSAMSSMPVGPLQGGFCANSNTASPSSHPSTSFANMATLPSCPAPSSSPALSSVPESSFYSSSGGGGSTGNIPASNPNHHHHHHHQQPPAPPQPAPPPPGCIVCTSCGCSGSCGSSGLTVSYANYFQHPFSGPSVFTFPFLPFSPMCSSGYVSAQQYGGGSTFPVVHAPYSSSGTPDPVLSGQSTFAVPPMQNFMAGTAGVYQTQGLVGSSNGSSHKKSGNLSCYNCGATGHRAQDCKQPSMDFNRPGTFRLKYAPPAESLDSTD
What are the official names of this protein?
Zinc finger CCHC domain-containing protein 14, BDG-29.
Protein: RL18_LAWIP
Sequence: MSIKSKNKLRQHRKIRIRKKIFGTADQPRLVIFRSNLHIYAQLVDDITGSTLLTTSTLSLKDNGINIRANKSGSTLVGKEIARLAIEKQIIKIVFDRNGYLYHGRVKAVADGAREGGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: NUOI_XANC5
Sequence: MNKITHYFKSLLLLELLGGLWLTLKYTFKPKYTVLYPMEKFPQSPRFRGLHALRRYPNGEERCIACKLCEAVCPALAITIDSAKREDGTRRTTRYDIDLFKCIFCGFCEESCPVDSIVETHILEYHFEKRGENIVNKPQLLAIGDRLETEIAERRAADAAFR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: UBIE_KLEP3
Sequence: MVEDSQETTHFGFQTVAKEQKQDMVAHVFHSVAAKYDVMNDLMSFGIHRLWKRFTIDCSGVRRGQTVLDLAGGTGDLTAKFSRLVGETGRVMLADINDSMLKMGREKLRNIGIVGNVEYVQANAEALPFADNTFDCITISFGLRNVTDKEKALRSMYRVLKPGGRLLVLEFSKPIIEPLSKAYDAYSFHILPKVGELVAKDGDSYRYLAESIRMHPDQETLKGMMQDAGFESVDYHNLTAGIVALHRGYKF
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: ATPF_LEGPL
Sequence: MDINLTLIVQMLVFAAFVLFTMKLVWPPLAKALEERQDKIADGLAAAERGRKELELAQHRVKDELKQAKAHSADIIDKANKRASEIIEAAKEAAKREAQIQAKLAQEQIAQQVNHAKEELRKQVAKLAITGAEKILMREVDAKANSELLDNLIEEI
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: HTPG_SHESA
Sequence: MSQQETHGFQTEVKQLLHLMIHSLYSNKEIFLRELVSNAADAADKLRYLALTNDALYEGDGELRVRISADKEKGTVTIEDNGVGMTRDGVIEHLGTIAKSGTAEFFKNLSGEASKDSQLIGQFGVGFYSAFIVAKKVTVRTRAAGHKANEAVLWESEGEGSFTVDTITKASRGTEITLHLRDEEKEFADEWRLRSIITKYSDHISVPVEMWQEGTPERDGPDGEKIPATEGYWKVMNKATALWMRNKSEISDEEYQEFYKHISHDYTDALLWSHNRVEGKQEYTNLLYIPSKAPWDLWNRDRKHGLKLFVQRVFIMDDAEQFMPSYLRFVQGLIDSNDLPLNVSREILQDNHITKAMRTGITKRVLGMLEKLAKDDAEKYQQFWAEFGQVLKEGPAEDFANRERIAGLLRFASTHTGSAAPTVSLDDYLSRMKEGQNKIYYIVADSHEAAANSPHLELLRKKGIEVLLMSERIDEWLINHLTEYKEKQLHSVTRGELELGELEDAAEKEAQEKLAEESAPLIERIKAALGASVADVKVTSRLTDTPACVVTGEGEMSSQMIKLMQAAGQPVPEVKPTFEVNPAHPLVSRLNDLQDEAAFADWSNLLLQQAQLSEKGSLADPSAFIKLMNQMLLANLK
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBJ_PINTH
Sequence: MADTTGRIPLWLIGTVTGIIVIGLLGVFFYGSYSGLGSSL
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein J, PSII-J.
What is the protein family that this protein belongs to?
Belongs to the PsbJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: BASP1_CHICK
Sequence: MGGKLSKKKKGYSVNDEKAKDKDKKAEGAATEEEETPKEAEDAQQTTETTEVKENNKEEKVEKDAQVSANKTEEKEGEKEKTVTQEEAQKAEPEKSEAVVDAKVEPQKNNEQAPKQEEPAAASAPAASSEAPKTSEPSSDAKASQPSEATAPSKADDKSKEEGEAKKTEAPATPAAQETKSEVAPASDSKPSSSEAAPSSKETVAATAAPSSTAKASDPSAPPEEAKPSEAPATNSDQTIAVQD
What is the function of this protein?
May play a specific role in the development of tissues.
What are the official names of this protein?
Brain acid soluble protein 1 homolog, 23 kDa cortical cytoskeleton-associated protein, CAP-23.
What is the protein family that this protein belongs to?
Belongs to the BASP1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Cortical cytoskeleton.
Protein: KATG_METRJ
Sequence: MSETIDKTDTTTFHMEGKCPFGGDRIGGALGNRPTLENWYPHRLRVEVLHQNGLAADPLGPDFDYAAEFAKIDFEALKRDIKQFLTSSVDWWPSDYGNYGPQMIRMAWHSAGTYRIADGRGGAGTGLQRFAPISSWWDNGNTDKSRRLLQPIKHKYGNALSWADLMVLTGNCALEIMGLPTYGFAAGRLDAWEADNATYWGPEVVEMGSVSSFDDMVNRDKRWRGKNGDADYDLENPLAASHQALIYVNPEGPYASGDPLASARDIRITFTRMAMNDEETVALIAGGHAFGKSHGMTPAKEIGPPPEMAPMEAMGLGWHNPKGSGAGKDTMTNGIEGSWTPDPTKWDNAYLENLFRFEWEQTRSPAGALQWTPKDPDAPKTPDAHVAGQMHPLMMMTSDIALKVDPDYRKVCEKFLNDFDAFTQAFSKAWYKLTHRDMGPKHRYLGPEAVIEDGLLWQDPLPERDYALVGEAEIAALKQAIAATGLSVSDLAFTAFSAASTYRDSDKRGGANGGRLALAPQKDWAVNRRAAPVVEALRGVMATFNDGRSDGKKISLADLIVLGGCVAVERAARDAGVETPVPFTPGRVDTTQALTDLEMFEWLKPVVDGFRNYVDDGFGQMTRSVSPEEMFLDKANLLTLTAPEWTVLTGGLRALNANHDGSNRGVLTDRVGVLTTDFFRNLTDVDLVWEKADADGMTFALKDRASGQTKFEATRSDLVFGSNAQLRSIADAYAGSDGQRRFVADFVKAWDKVMMLDRFDVKGHRRYGPMAA
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: TX21G_TRILK
Sequence: MKPIVSILLFCALAVVIMGHPMNQGYGIPHDVVKLPNGQWCKTPGDDCSKSSECCKAKDTVTYSSGCSQEWSGQLGGFVKLCHICNVESSMC
What is the function of this protein?
Probable neurotoxin with ion channel impairing activity.
What are the official names of this protein?
Toxin ICK-16.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 21 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RPO5_METTH
Sequence: MKREILKHQLVPEHVILNESEAKRVLKELDAHPEQLPKIKTTDPVAKAIGAKRGDIVKIIRKSPTAEEFVTYRLVQD
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo5, DNA-directed RNA polymerase subunit H, RPB5.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LCL2_CANDC
Sequence: MFQKLIVITFAIALASANIFDFLNNFNAGGRQQQNQGVRTPQEYESVVLNSQCDKYLCPDTGLCVEAPKFCPCPYPSSQIRCFLPDGRFVCISKPAGEGISEKYNDPKTNWKIDAKDDNIRDCGWVNRAWRGLV
What is the function of this protein?
Probable component of the endoplasmic reticulum-associated degradation (ERAD) pathway.
What are the official names of this protein?
Long chronological lifespan protein 2.
What is the protein family that this protein belongs to?
Belongs to the LCL2 family.
Protein: CH602_BURP1
Sequence: MAAKEIIFHDGARAKLVEGVNLLANAVKVTLGPKGRNVVLERSFGSPVVTKDGVSVAKEIELADKVQNIGAQLVKEVASKTSDAAGDGTTTATVLAQAIVREGQKYVAAGLNPLDLKRGIDKAVAAAVDELKKISKPTTTSKEIAQVATISANGEESIGQRIAEAIDRVGKEGVITVEDGKSLADELDVVEGLQFDRGYLSPYFINHPERQLAVLDEPFILLHDKKISNIRDLLPVLEQVAKAGRPLLIVAEDVEGEALATLVVNNIRGILKTVAVKAPGFGDRRKALLEDIAILTGGQVITEETGLTLEKATLQELGRAKRIEVGKENTTLIDGAGDKPNIDARVKQIRAQIAEATSDYDREKLQERVAKLAGGVAVIKVGGATEVEVKEKKDRVDDALHATRAAVEEGIVPGGGVALIRVKQAIAALAGANADQKAGISIVLRALEEPLRQIVANAGEEASVVVATVAAGQGNYGYNAATGEYGDLVESGVLDPTKVTRTALQNAASIAGLLLTTDATVHEAPKDAPPAAPAGVPGAGGPGFDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y497_PSYWF
Sequence: MPANPELLISPKQRQGGGYEQLAADFLQQQGLRLIARNWQQPKVGEIDLVLIEHGRSWNVLVFAEVRKRKLLGYGDALASITRSKQKKLIKTARYFLRHHPEYADFECRFDVVGFTERTGRSGQGEPLQSEWLQGAFLAPAW
What are the official names of this protein?
UPF0102 protein PsycPRwf_0497.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: HM1B_PHLSP
Sequence: MKVSVLITLAVLGVMFVWTSAAEQEDHGSDRRDSPALLKSLGRVFQSEERACRELLGGCSKDSDCCAHLECRKKWPYHCVWDWTFGNEKS
What is the function of this protein?
Gating-modifier toxin that inhibits voltage-gated sodium channel Nav by shifting the threshold for channel activation to more positive potentials.  This toxin moderately inhibits human Nav1. 7/SCN9A (IC(50)=360 nM) and weakly inhibits hNav1. 2/SCN2A (37% inhibition at 1 uM peptide) and hNav1. 5/SCN5A (<20% inhibition at 1 uM peptide).  Inhibition of Nav1. 7 is voltage-dependent, with lower inhibition at more positive test pulses.
What are the official names of this protein?
Mu-theraphotoxin-Phlo1b, Mu-TRTX-Phlo1b.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 39 (Jztx-34) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CWP07_PHAVU
Sequence: VAGRSVVKIAEGYL
What are the official names of this protein?
53 kDa cell wall protein.
What are the subcellular locations of this protein?
Secreted, cell wall.