PharMolix/UniProtQA huggingface dataset:
Protein: TOF1_CHAGB
Sequence: MEDVGVNNDTVHPEARAYITSLVSALGGYGVDDDGGYTLGDDALEVLRDLKRWVRFYDERTNRMDVARCLAESNLVTSDLLQIMAKWVSNESSSKYMERIAFACLEIMVPLTWPIERDSETMTVNHHRHLPVLQLAQLGYKRAIINFDVAPILSTAVRIALPCMAIPNGDRSSRDQATIKLILYFLRNIAMIAPPPGLKYEGDETQVSRSTLIDAFTFQDIFLTILTIASNMGEDFRTEDVIILDIIFHIVKRVDSSKLFVSEKRLHKIKEDELTAAMRKEAAMLKSYNKNAPTRHSRFGTMIWVKRESGKLATVSGQDALLDAATRERKMDSNKSFKPPRRARKEDMEPKDLGPRVSLDERARRQLQSFVSEFLDSGFNPLFSHVRRSLDREAPHVLQSHHSQFFYLVAWFLEAERMRKKAAKDSKNQTSTGEDVGSFNLVAEVLNQEMFITMSRTLDRAYGDKDWRLLTTVMRCFTQILLTIQEMASSGNEENEEIADNILSRLFYEETTHDLIANIVRTYKDQGFEYLDACTELTHTFVRILEAYSKENVDLQVRSRKRTRRKKKAAKAAGDQGDDEGQGDAEDDSADDERQAEKTSQERKFDFKRFALRFAPQGVVDTFVTFTKYYRDLDDSQLKRAHRYFFKLAFKQDMSVMLFRLDIIHLFYNMIKGPEPLDKSSSMYKEWEDLAMQTIRKCVKKLEERPALFTELLFSKITSTAHYLEYGHEKQTISNPRPAAELEFKREVEREQQIAILVGVLIDRSQTDHLGWIKKQLSDAESERRAWENAERALAAERPDDEVMAGSAEAIAAKTPDHVTMRPDTDARRTAMFKNPHLRLLMKLVGLERLAPTLDETPDAIWIIPGTLTADALKETISLINKAEFTPPIFDDGELAEDQLRRKTAPRKRAAYDDDDNLDGINDLINDGSDDDGDDGTGILFPAGGPTARKRTAQDEPPKKRLQRRRRRGGSDDPDADTAETDAQAEARARARRKKELEKARKIKSEMYVDPREDDSDYEGNKERDRLFFAREEERQAVKDATFGLSSRPEGVGEGAWEALVGAVMGGGDGDDGEGEDAVVGERPPKVGGRKRKSGVADLAESGGEDSEEGDEDDESRSEEDGSAVSEAEAPAAAGRRPNKRRKPAQKKKKRVVDISSGEDDDVGMDMDVDVDADADADAMDFTQSSKDGAVTNDTPLSSDPSRTTKPGGAEGSGDKGGGEDEDEDMPVAKPVARARPRARAGFIVESSDEE
What is the function of this protein?
Forms a fork protection complex (FPC) with CSM3 and which is required for chromosome segregation during meiosis and DNA damage repair.  FPC coordinates leading and lagging strand synthesis and moves with the replication fork.  FPC stabilizes replication forks in a configuration that is recognized by replication checkpoint sensors (By similarity).
What are the official names of this protein?
Topoisomerase 1-associated factor 1.
What is the protein family that this protein belongs to?
Belongs to the timeless family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TILS_HELSJ
Sequence: MLKNIIYSYITQLKNLLSKKLNVLCTFSAGQDSFFLLYCLIHIISNKNNKIKLQHNHHFLQSSNILSFWQCIKVASIFKIPLVINLLEINLANKDFMTENEARKWRYDSFLRNSLFQNEKPSIFIGHTGSDLLETFFWHFLRNSIIDYQLIKKKLLWNIPYYISNFSSVGYKNSSKVKIKLTNKKKKINCLINHNLMLNKAKKSFLKKDLTQLVLITRPLVNLHRQDIFLFRKNLKLPVITDKSNDNNYYYRNRIRNILFPIMRILFNKKTDKNLIKLFL
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity).
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, plastid, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Plastid.
Protein: GATE_HALMA
Sequence: MTEYDYEELGLVAGLEIHQQLDTATKLFCDCPTTIREPEESDRSFTRYLHPTKSELGEIDEAALEESMVDREFEYLAYDTTCLVEEDDEPPHRVDREAMETTLEIAQLLDMSVADQVNIMRKIVVDGSNTTGFQRSMLVANDGAIETSAGPVGVEDMLLEEESCQRIEETEDGVRFSLDRLGIPLVEIGTKPDISSPEQAREAAERIGMLLRSTGKVKRGLGTIRQDVNVSIEEGARIELKGVQSLDDIDDLVRNEVRRQVELLDIAEELAERGATVGEPQDVTEVFEDTDSGVIEGALSSGGKVQGLLLSGFDGLVGREIQPDRRLGTELSDHAKRHGAGGIFHTDELPAYGVTEAEVEALRDAVGAGSEDAVAIVADDPETAELAIDAVAERAETALAGVPEETRDANEDATSRYLRPLPGAARMYPETDVPPVEPDVTEVETPELLTEKVDRYESEFDLGSGLAEQVAYGQRWPLFEALVAGEGVDPTLAAGTLESTLTELRRDDVPVENLTDKHLQGAILLVDGGDVPREGMEDLLTALAENPSLTAEEAVEQEGLGGVDESEVRDAVAEVVERHEDQVAEEGMGAFSALMGECMGALRGKADGDTVSDVLRSEIQKRA
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).  The GatDE system is specific for glutamate and does not act on aspartate.
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit E, Glu-ADT subunit E.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatE subfamily.
Protein: MNMG_ACAM1
Sequence: MTSPQAVEFLDEFEVIVVGAGHAGCEAALASARMGCSTLLLTLNLDKIAWQPCNPAVGAPAKSQLTHEVDALGGEIGKMADRTYLQKRLLNHSRGPAVWALRAQTDKREYAAVMKTIVENQGNLTVREGMVTDLVLGDNDEVVGVQTYFGVAFRCQAVILTTGTFLGGRIWVGDKSMPAGRAGEFAAEGLTETLNQLGFETGRLKTGTPARVDKRSADFSVMEPQPPDQQVRWFSFDPAVWIEREQMNCYITRTTPETHQLIQDNLHLSPVYGGWVDAKGPRYCPSIEDKIVRFADKASHQIFIEPEGRDIPELYIQGFSTGLPEALQLRMLRSLPGLEHCAMLRPAYAVEYDYLPATQCYPTLMTKRIEGLFCAGQINGTTGYEEAAAQGIVAGINAARRVNQQEMLIFPRAESYIGTLIDDLCTKDLREPYRMLTGRSEYRLLLRSDNADQRLTPLGREVGLIDDRRWHLFTRKQATITAEKERLHATRLKERDPAAQAIVQTTGEKIKGSITLSDLLRRPKFHYCDLQQHGLGIETLERSERESVEIEIKYAGYIQRQQRQIEQVSRQEQRKLPENIDYASIETLSMEAREKLAKVRPLTVGQASRIGGVNPSDINALLFYLETLARLSPVS
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_METHJ
Sequence: MAKKVQKKLPRRKEEFTYHGYKIDELRAMSLEDLLPVMPSRARRKVLRGWTIGEEKLLSDIRSNGSRIRTHQRDMIILPEMIGREIEIYNGKEFIRVELQPESVFHYLGEFALTRRRVTHGSAGIGATRSSKFVPLK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: CHS1_ARATH
Sequence: MSTSYSFLLAGRELDVFLSFSGKIALDVDFGYDLSRNGIKAFKSESWKESSFKPIDLRTLEALTESKVAVVMTSDEEVSSVGFLEELIVIIEFQEKRSLTVIPVFLTKHPLDVEKVSQIFPERAKIWRTAIAKLDNIAAQYSFSRNLAVMHGTHRIKQIADDIRLMFLSSASSDFKGLAGMDRHMKALYALLALESDEKVRTIGIWGSSGVGKTTLARYTYAEISVKFQAHVFLENVENMKEMLLPSENFEGEDLRSVNHEMNEMAEAKQKHRKVLLIADGVNNIEQGKWIAENANWFAPGSRVILITQEKSLLVQSGVNHVYEVGSLRYDEALQLFSRFAFKQPYPSPDFERLSVRAVQLAGFLPVTIRLFGSFLTGRDKEEWEATLLKLNAKQGKDIKEVWKIMEALEDKDIVEASQR
What is the function of this protein?
Confers resistance to low temperatures by limiting chloroplast damage and cell death, thus maintaining growth homeostasis (PubMed:16667557, PubMed:23617639, PubMed:23651299).  Regulates steryl-esters and sterols accumulation (PubMed:16667557).  Limits leaf necrosis associated with virulent bacterial infection (e. g.  Pseudomonas syringae pv.  tomato DC3000) (PubMed:23617639).
What are the official names of this protein?
Disease resistance protein CHS1, Protein CHILLING SENSITIVE 1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL31_RHILW
Sequence: MKAGIHPDYHMIKVVMTDGTEYETRSTWGSEGAVMNLEIDSKSHPAWTGGNQQLMDRGGRVSKFNKRFGGLGL
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: KEFC_CROS8
Sequence: MDSHTLIQALIYLGSAALIVPVAVRLGLGSVLGYLIAGGLIGPWGLRLVTDAQAILHFAEIGVVLMLFVIGLELDPQRLWKLRASVFGGGALQMGACGLLLGGFCVALGLRWQVALLIGLTLALSSTAIAMQAMNERNLTASQMGRSAFAVLLFQDIAAIPLVAMIPLLAASGEATTASAFFLSALKVVGALALVVLLGRFVARPALRFVARSGLREVFSAVALFLVFGFGLLLEEAGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLFFIGVGMSIDFGTLVAHPLRVLTLLFGFLIIKTVTLWLVAKPLKVPGRQRRWFAVLLGQGSEFAFVIFGAARSAEVLDAEWAKALTLAVALSMAATPLLLVLLTRLEKSGQQQAREADEIDEEQPRVIIAGFGRFGQIAGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDATRVDLLESAGVAKAEVLINAIDDPQANLQLTELVQTHFPQVRIIARARDVDHYIRLRQAGVAQPERETFEGALRVGRMALEELGIGSYEARERADLFRCYNQQMVDEMAEGDNDTSARAATFRRTSAMLTEIISEDRAHLSLIQRHGWQGTREGKHTGNDADEPEVKPQP
What is the function of this protein?
Pore-forming subunit of a potassium efflux system that confers protection against electrophiles.  Catalyzes K(+)/H(+) antiport.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system protein KefC, K(+)/H(+) antiporter.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y5907_BACAC
Sequence: MSTILVLGGSNGRTLEKLAKKRDCQVIFHDGKNHGGVKKTFRSVIKKCDVIVIQKGACGHVSIDVAKEYAKKYDVPLLFNQGFGGTGALEMGLKHLKAA
What are the official names of this protein?
UPF0751 protein BAMEG_A0107.
What is the protein family that this protein belongs to?
Belongs to the UPF0751 family.
Protein: Y084_NPVAC
Sequence: MIASINNRTKLNFFHLLVTMFRIYPNNTTVPGCLVGDIIQVRYKDVSHIRFLSDYLSLMPNVAIVNEYGPNNQLVIKRKNKSLKSLQDLCLDKIAVSLKKPFRQLKSLNAVCLMRDIIFSLGLPIIFNPALLQRKVPQRSVGYFMNSKLERFANCDRGHVVEEKQLQSNLYIDYFCMICGLNVFKIKE
What are the official names of this protein?
Uncharacterized 21.7 kDa protein in GP41-PNK intergenic region.
Protein: Y045_THEFY
Sequence: MNPGGGLDMQAILQQAQQMQQQLMAAQQELDETKVTGSSGGGLVSVTMNGRGQVEDVSIDPKAVDPDDAAETAQTIADLVLAAIRDGERMVEEIQQQKMGPLAQGLGGGFPGLPGL
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Tfu_0045.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: HOPW2_PSEYM
Sequence: MSPAQIIRTSHSFPPSFTGTSSSAENSHAQSPQQVLTRAFVASGELNAAFGRTSTASAQDFTSLLGTLQRELEKKTPAFPDLAELANQLADAAMGDQGGHWLGRDEQQTLKGMIDRCKSQLAHTPASDASYDLLAQVCENLKKARLHQSISQMTGEAHAKVRGVPDLLALIQLDPDILAEKPVGMPSYVKFSSFICMAKARTAELSENLRNASNEVALLLHPHADTILEQGSLRLQIVGF
What are the official names of this protein?
Putative truncated effector protein hopW1-2.
What is the protein family that this protein belongs to?
Belongs to the HopW family.
Protein: VP4_ROTHC
Sequence: MASSLYAQLISQNYYSLGNEILSDQQTNKVVSDYVDAGNYTYAQLPPTTWGSGSILKSAFSTPEITGPHTNTVIEWSNLINTNTWLLYQKPLNSVRLLKHGPDTYNSNLAAFELWYGKSGTTITSVYYNTINNQNKTHDANSDCLILFWNEGSTQLEKQVVTFNWNVGGILIKPINSSRMRICMSGMENFNNDSFNWENWNHEFPRSNPGININMYTEYFLASSDPYTYLKNLQQPTAKTVDMKMMKKMNDNSKLGDGPINVSNIISKDSLWQEVQYVRDITLQCKILSEIVKGGGWGYDYTSVTFKTVNHTYSYTRAGENVNAHVTISFNNVKERAYGGSLPTDFKIGRFDILDTDSYVYIDYWDDSEIFKNMVYVRDVRADIGGFQYSYSSEMSYYFQIPVGSYPGLHSSRLQLVYDRCLLSQQFTDYAALNSLRFVFRVVSTSGWFITTGDINTRRVASGTGFAYSDGHVANTVGTISFISLIPSNPNYQTPIASSSTVRMDLERKINDLRDDFNALASSVALSDILSLAMSPLTFSNLLESVPAITSSVKDVAASVMKKFRSTKMFKKAAKQNYREFVIGDLLEDVTNVARNNNSLNYSDITSAMMVSTTNRLQITDVDTFSEIVSRSADNFISNRSYRMIENNTVHEITPTRRFSYDIKTLQQRNFDIDKFSKLASQSPVISAIVDFATIKAIRDTYGISDDIIYKLVASDAPTILSFINQNNPLIRNRITNLINQCKL
What is the function of this protein?
Forms the head of the spikes and mediates the recognition of specific host cell surface glycans.  It is the viral hemagglutinin and an important target of neutralizing antibodies.
What are the official names of this protein?
Outer capsid protein VP4, Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP4 family.
What are the subcellular locations of this protein?
[Outer capsid protein VP4]: Virion. Host rough endoplasmic reticulum. Host cell membrane. Host endoplasmic reticulum-Golgi intermediate compartment. Note=The outer layer contains 180 copies of VP4, grouped as 60 dimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple- layered particles. SUBCELLULAR LOCATION: [Outer capsid protein VP8*]: Virion. Note=Outer capsid protein. SUBCELLULAR LOCATION: [Outer capsid protein VP5*]: Virion. Note=Outer capsid protein.
Protein: CMR1_COCIM
Sequence: MPRTKEEPELSEFEKQRAANIAERDALLKKLTLEAQSAGIFSKPPASKSSSQTKKKPAPKRVKKEDEPPVPRRMSSRLRGLAAESEIAKRKAEDEYQAMKAAAQAKRMRISGDLNVGDIVVGENKWNETGLQGLGIVNSAQRYQRTFGEEDIKKTTNKELKELREKMSGLQLWEPWEPNRIKITRERIYSMLFHPTESKPLIFAGDKTGHLGILDASQQPDQNESDEEDEYPDPTITTIKPHTNTISAMHIHPSDPSKLYSGSYDSSIRALDLEKSVATEAYAPASSSDDEPLSGIDMAPTDPHVLYFTTLDGFFGRHDMRVSSKANPGDGSAVTFYQLSEKKIGGFSLCPTQPHYMATASLDRTMKVWDLRHLSTKHPKPVGEHESSLSVSHAAFNQKGQIATTSYDNSIKIYDLASKGLKDWKPNHTLSEDEMAPDAVIRHNCQTGKWVTILRPQWQACPDSPVERFCIGNMNRFVDIYTSTGEQLAQLGADVITAVPAVAVFHRTQNWVVGGTGSAKVCLWM
What is the function of this protein?
DNA-binding protein that binds to both single- and double-stranded DNA.  Binds preferentially to UV-damaged DNA.  May be involved in DNA-metabolic processes.
What are the official names of this protein?
DNA damage-binding protein CMR1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat DDB2/WDR76 family.
Protein: CE046_MOUSE
Sequence: MAVSVLRLMVVLGLSALILTCRADDNPNENDNPDSKPDDSSKNPEPGFPKFLSILGSEIIENAVDFILRSMSRGSSFMELEGDPGQQPSKVTS
What are the official names of this protein?
Uncharacterized protein C5orf46 homolog.
What are the subcellular locations of this protein?
Secreted.
Protein: SYW_WOLSU
Sequence: MIKKRVFSGIQPTGNIHLGNYLGAVKNWVDSQDEFDNIFCIVNSHAITIKQDPALLRAKTYELAAVLLACGIDMKKSKLFIQSEVDEHAALAWILDCNIPMGDMSRMTQFKDKSQKNPKNINIGLFNYPALMAADILLYQTDFVPVGEDQKQHLELTRDVAERFNRDYGETFKIPEPMIPKMGARIMGLDDPTKKMSKSEGKPNHGIALLDTPDEILKKFKKATTDSENLVRFNPEQIGIFNLLTIYQIFTGYSQEVIEAEFEGKGYGIFKVAVAEAVIEGLKPIQERYAKLTKEQGYLEEVLSHGASEVRKIAQKTYKEVKERVGLI
What is the function of this protein?
Catalyzes the attachment of tryptophan to tRNA(Trp).
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_BRUA4
Sequence: MVKGVIVLAAGGTGGHLFPAEALAHELKARGWDVHLATDARAQRFAGAFAEDHVHVIRSATIAGRNPIALLKTFWSLWQGNLDSRKLFRRLKPKLVAGFGGYPTLPPLYAASNMNIPTMVHEQNAVMGRANKGLAGRVKAIAGGFLPETGGVYAEKTVTTGNPVRPPVLAAAETSYKPVKADERFRLLVFGGSQGAQFFSTAIPAAVALLPDRDRARLLITQQARKEDEAAVREAYKKLGVPADVAPFFNDMPARMADAQFVISRSGASTVSEITVIGRPAMLVPFPHALDHDQAANAAALAAVGGGEVVRQSELSPERLAEILQAAMNEPQRLEAQAKAAKSVGKPDAARLLADLAEAIAAGKSVQEFKEGTRP
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CH60_DESAL
Sequence: MAKEIKYDMKARELMLAGVNALADAVAVTHGPKGRNVVIDKAWGAPTVTKDGVTVAKEIELENKFENMGAQMVKEVASKTSDTAGDGTTTATVLARAIYEEGMKLVVAGNNPMAIKRGIDKACEAAVKSLMNLSKPTKEQREIAQVGTISANTDETIGNIIAEAMNKVGKEGVITVEEAKSMDTTLDVVEGMQFDRGYISPYFVTDSEKMVCSLEDPYILIHEKKISNMKDLLPLLEQTAKMGKPLLIVAEDVEGEALATLVVNRLRGTLQIAAVKAPGFGDRRKAMLEDIAILTGGTVVSEDMGIKLENMSLADLGKCKRVSIDKDNTTIVDGAGARSALEGRVKQIRAQIDDTTSDYDREKLQERLAKLIGGVAVINVGAATEVEMKEKKARVEDALNATRAAVEEGIVPGGGVALVRAIDAVAKAKITGEQKIGARVVMRALEAPLRMIANNAGMEGSVVLDKVKNTEGSFGYNADTDTYEDLIEAGVIDPTKVVRLALQNACSIAGLMLTTEAMIADKPDENAGGMPAMPGGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAY_CHRSD
Sequence: MLLFLADLLAHFQSAFNVFNYLTLRVILGTLTALMLCLWLGPQVIRRLVERQIGQAVRDDGPQSHLSKAGTPTMGGAMILIAIAVSTLLWGDLTNHYVWLVLAVTLGFGAIGWVDDYRKVVEKNPRGLPARWKYFWQSAIGLGAAVTLYLTAASPVEVSLIVPLFKDVVVPLGLFYIVLTYFVIVGSSNAVNLTDGLDGLAIMPTVLVAMGLAIFAYASGNTVFAQYLHIPLVPGAGELAVFCGTIAGAGLGFLWFNTYPAQVFMGDVGALALGAALGVVAVIVRQEIVLFIMGGVFVMETVSVMLQVGSYKLTGRRIFRMAPLHHHFELKGWPEPRVIVRFWIITVVLVLLGLATLKIR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IF5A2_SOLLC
Sequence: MSDEEHHFESKADAGASKTFPQQAGTIRKNGYIVIKGRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDGFVSLLTESGNTKDDLRLPTDENLLKQVKDGFQEGKDLVVSVMSAMGEEQINAVKDVGTKN
What is the function of this protein?
The precise role of eIF-5A in protein biosynthesis is not known but it functions by promoting the formation of the first peptide bond.
What are the official names of this protein?
Eukaryotic translation initiation factor 5A-2, eIF-5A-2.
What is the protein family that this protein belongs to?
Belongs to the eIF-5A family.
Protein: RNH2_SYNE7
Sequence: MSPKTRLDSDFFGPGDRWQTVAGVDEVGRGCLFGPVVTAAVILPETAIAPLQQAGVTDSKRLSQRQRQQLYPLICEVALATGWGLASVAEIERWNILQATFLAMRRAIAKLDRPISRCLIDGNQQVPQLTYPQTTVIQGDRHCITIAAASILAKVWRDRLIERLDERYPGYALGRHKGYGTAQHRQAILQLGPTPLHRIRFLRSLRQPSQQIDLF
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KPRS_COREF
Sequence: MTAHWKENHKNLMLFSGRAHPELAEAVARDLEVEVTPMTARDFANGEIYVRFEESVRGSDCFVIQSHTQPLNKWLMEQLLMIDALKRGSAKRITAILPFYPYARQDKKHRGREPISARLIADLLQTAGADRIVSVDLHTDQIQGFFDGPVDHMHAMPILTDYIKDKYDLSNIVVVSPDAGRVKVAEKWANTLGDAPMAFVHKTRSTEVANEVVANRVVGDVAGKDCVLLDDMIDTGGTIAGAVGVLKEAGARSVVIACTHGVFSDPARERLSSCGAEEVITTDTLPQSTEGWSNLTVLPIAPLLARTISEIFENGSVTTLFEGDA
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase, RPPK, 5-phospho-D-ribosyl alpha-1-diphosphate synthase, Phosphoribosyl diphosphate synthase, Phosphoribosyl pyrophosphate synthase, P-Rib-PP synthase, PRPP synthase, PRPPase.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_SALG2
Sequence: MRLNTLSPAEGSKKAGKRLGRGIGSGLGKTGGRGHKGQKSRSGGGVRRGFEGGQMPLYRRLPKFGFTSRKAAITAEVRLSDLAKVEGGVVDLNTLKAANIIGIQIEFAKVILAGEVTTPVTVRGLRVTKGARAAIEAAGGKIEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: TRMN6_VIBVY
Sequence: MKSGTLKTKGFKFKQFSIASSNSGMPVSTDGVLLGAWADFHHSQNLLDIGTGTGLLSLMCAQRYAHLSITAVDIDAHAMEAAQENFSHSPWHSRLHLQHGDVLKLNFTHRFDGIICNPPYFNSGEQAQATQRATARHTDTLAHDALLLRCRELLTPNGKANFVLPLTEGEQFLQLAQQQGWHLHRLCRVKPSPNKPVHRLLFELGLSTATTSEEHLTINDGSTYSAAFVKLCQDFYLKM
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHAM_YERPP
Sequence: MIRKAFVMAVNPDAHAEYQRRHTPIWPELESVLKAHGAHHYSIFLDETRNLLFGVVEIESEERWNAVAQTAECQRWWQHMADVMPSHPDNSPVSQALREVFYLE
What is the function of this protein?
Involved in the anomeric conversion of L-rhamnose.
What are the official names of this protein?
L-rhamnose mutarotase, Rhamnose 1-epimerase, Type-3 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose mutarotase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_STRPS
Sequence: MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNARTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTRAQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: THA_CHICK
Sequence: MEQKPSTLDPLSEPEDTRWLDGKRKRKSSQCLVKSSMSGYIPSYLDKDEQCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDGCCVIDKITRNQCQLCRFKKCISVGMAMDLVLDDSKRVAKRKLIEENRERRRKEEMIKSLQHRPSPSAEEWELIHVVTEAHRSTNAQGSHWKQKRKFLPEDIGQSPMASMPDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLSGEMAVKREQLKNGGLGVVSDAIFDLGKSLSAFNLDDTEVALLQAVLLMSSDRTGLICVDKIEKCQETYLLAFEHYINYRKHNIPHFWPKLLMKVTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFEDQEV
What is the function of this protein?
Nuclear hormone receptor that can act as a repressor or activator of transcription.  High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
What are the official names of this protein?
Thyroid hormone receptor alpha, Nuclear receptor subfamily 1 group A member 1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: NADE_PYRAE
Sequence: MFVYDVVNALDYEKARSIITAFISQYVQRAGSRGVVVGISGGVDSTVAAALAVEALGRQRVLGLLMPSLYTPPEDLKDALDVINALGVEWKRVDITPIYDAFVKTLPDFSQENRVAAGNILPRIRMTVLYYYANKYNLLVMGTGDRSELLLGYFTKYGDGGVDFLPIGSLFKLQVRELAARLGFADIAKKPSSPRLWQGHTAEGELGASYEVIDQVLYAVFDLKKPPEEVRGFFGEVVDIVITRVKKNIHKLTPPAYPDITPARRNV
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: LACG_RHIRD
Sequence: MMTTLRRRLPDIVQYSVLSLAAFLSIFPFIWMVIGTTNTTSQIIRGKVTFGTALFDNIASFFAQVDVPLVFWNSVKIALVGTALTLLVSSLAGYGFEMFRSKLRERVYTVILLTLMVPFAALMIPLFMLMGQAGLLNTHIAIMLPMIASAFIIFYFRQASKAFPTELRDAAKVDGLKEWQIFFYIYVPVMRSTYAAAFVIVFMLNWNNYLWPLIVLQSNDTKTITLVVSSLASAYSPEYGTVMIGTILATLPTLLVFFAMQRQFVQGMLGSVK
What is the function of this protein?
Part of the binding-protein-dependent transport system for lactose.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Lactose transport system permease protein LacG.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.