PharMolix/UniProtQA huggingface dataset:
Protein: ATPA_CHESB
Sequence: MDIRAAEISAILKDQIKNFGKEAEVSEVGQVLSVGDGIARVYGLDNVQAGEMVEFPGGIRGMALNLEVDNVGVVIFGADRDIKEGDTVKRTGAIVEVPVGPGLLGRVVDALGNPIDGKGPIQATERRRVDVKAPGIIPRKSVHEPMSTGLKAIDALIPIGRGQRELIIGDRQTGKTAIILDTFLNQKPLNDGDDESQKLYCIYVAVGQKRSTVAQFVKVLEERGALEYSIVVAATASDPAPMQFLAPFAGCAMGEYFRDNGKHAVIAYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDDNGSGSLTALPVIETQANDVSAYIPTNVISITDGQIFLETNLFFQGVRPAVNVGLSVSRVGSAAQVKAMKQVAGSIKGELAQYREMAAFAQFGSDLDAATQRLLNRGARLTELLKQPQFSPLKTEEQVVVIFAGVNGYLDALALRDVGRFEQGLLTHMRSEGKEILDAIRVEKALSDDLRAKLKAEIDAYAKNFS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS13_LEGPL
Sequence: MARIAGVNIPDHKHVVIALTAIYGIGKTTSLKLCKTVDIDPSVKVSQLSDAQLESLRTEIAKITVEGDLRRVVTMNIKRLMDLGCYRGLRHRRGLPLRGQRTKTNARTRKGRRKGTSS
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: EAE_ECO11
Sequence: MITHGFYARTRHKHKLKKTFIMLSAGLGLFFYVNQNSFANGENYFKLSSDSKLLTQNVAQDRLFYTLKTGETVSSISKSQGISLSVIWSLNKHLYSSESEMLKAAPGQQIILPLKKLSVEYGALPVLGSAPVVAAGGVAGHTNKMTKMSPDATQSNMTDDRALNYTAQQAASLGSQLQSRSLHGDYAKDTALGIAGNQASSQLQAWLQHYGTAEVNLQSGNNFDGSSLDFLLPFYDSEKMLAFGQVGARYIDSRFTANLGAGQRFFLPENMLGYNVFIDQDFSGDNTRLGIGGEYWRDYFKSSVNGYFRMSGWHESYNKKDYDERPANGFDIRFNGYLPSYPALGAKLMYEQYYGDNVALFNSDKLQSNPGAATVGVNYTPIPLVTMGIDYRHGTGYENDLLYSMQFRYQFDKPWSPQIEPQYVNELRTLSGSRYDLVQRNNNIILEYKKQDILSLNIPHDINGTEHSTQKIQLIVKSKYGLDRIVWDDSALRSQGGQIQHSGSQSAQDYQAILPAYVQGGSNIYKVTARAYDRNGNSSNNVQLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVKKNGVTQANVPVSFNIVSGTATLGANSATTDANGKATVTLKSSTPGQVVVSAKTAEMTSALNASAVIFVEQTKASITEIKADKTTAVANGNDAVTYTVKVMKEGQPVHGHSVAFTTNFGMFNGKSQTQNATTGSDGRATITLTSSSAGKATVSATVSGGNDVKAPEVTFFDGLKIDNKVDILGKNVTGDLPNIWLQYGQFKLKVSGGNGTYSWHSENTNIATVDESGKVTLKGKGTAVINVTSGDKQTVSYTIKAPNYMIRVGNKASYANAMSFCGNLLPSSQTVLSNVYNSWGPANGYDHYRSMQSITAWITQTEADKISGVSTTYDLITQNPHKDVSLNAPNVYAVCVE
What is the function of this protein?
Necessary for the production of attaching and effacing lesions on tissue culture cells.  Believed to mediate adherence.
What are the official names of this protein?
Intimin, Attaching and effacing protein, Eae protein.
What is the protein family that this protein belongs to?
Belongs to the intimin/invasin family.
What are the subcellular locations of this protein?
Cell outer membrane; Single-pass membrane protein.
Protein: Y957_ACTSZ
Sequence: MNDKRVFNHVENNAGNEEEVFRVKREFSETAEIIPDLTALDDEREEKQALEGELLASQFEQAVRPRFRWWKRAVIAVAVLFLGATVAQSVQWLIDTWQANQWIYFAFAVVGCSVVGLGLSALGREFLRLRKLRQHLALRAESAVEFKDDFEIDKAKKLCGEITSSLGMDAQHPTVIQWQKQLNDGLTAREVGELFSKNVLYPIDNKAKKLITQSAVENGIVVAISPLAIVDMLFLAWRNTRLINRIANIYGIELGYWSRLRLMRMVFINMAFTGATELVQDIGLDWLSQDITAKLSGRIGQGLGVGLLTARLGIKTMEFCRPLTFNKDEKPRLSHIHRELLTSLKSVVLRSDKSRKKQNV
What are the official names of this protein?
UPF0283 membrane protein Asuc_0957.
What is the protein family that this protein belongs to?
Belongs to the UPF0283 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MYCT_RAT
Sequence: MSRKASEDVEYTLRSLSSLMGERRRRQPEPGAPGGERSLLAAESAASLQGAELERAARRQFQRDETPAFVYAAAAFSALGGFLFGYDTGVVSGAMLLLRRQMRLGAMWQELLVSGAVGAAAVAALAGGALNGALGRRSAILLASALCTVGSAVLAAAANKETLLAGRLVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAIPAVIQFLGFLFLPESPRWLIQKGQTQKARRILSQMRGNQTIDEEYDSIRNSIEEEEKEASAAGPIICRMLSYPPTRRALAVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASITAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALTILALGFLLSAQVSPRVTFRPTAPSGQNATCTEYSYCNECMLDPDCGFCYKINSSAVIDSSCVPVNKASTNEAAWGRCENETKFKAEDVHWAYSFCPTPYSWTALVGLVLYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSAGINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFAAVGLLFVYGCLPETKGKKLEEIESLFDHRLCTCGTADSDEGRYIEYIRVKGSNYHLSDNDASDVE
What is the function of this protein?
H(+)-myo-inositol cotransporter (PubMed:11500374).  Can also transport related stereoisomers (PubMed:11500374).
What are the official names of this protein?
Proton myo-inositol cotransporter, H(+)-myo-inositol cotransporter, Hmit, H(+)-myo-inositol symporter, Solute carrier family 2 member 13.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VPS10_NEOFI
Sequence: MITRWLLITSFLALAILSLSSAAKKSEPEITPSSFDNEPFSLFYFEDTETILMNTRDGNLFRSFDGGKGWEQVDDPNGKMKKGVRSIWQHPFDKNRAYALGANRRHWVTKDQAKTWESFEVDGYAATQHEPLIFHGWDSSKVIFQSDECMGRFCIVKSYYSTDDFKTVSPLRVSAGGCAWAVGHPQFAEGLNLEDELRDRVLCIVPGLKVPSAHANRLVYSDDFFRSDAEGTELNIQQGRPVSGILSAAAVKKFFVTAAKSQGTNELALYVTLDTKAWHRADFGGHRVEQDGYTLLESTNYSMQVDVLTSPSSNTGILFTSNSNGTYFTRNVEHTNRDRFGHVDFEKIADIQGIVLVNTVKNWDKVGSENEKKVVSSISFDDGRTFQSLKVGDKQLHLHSVTTFANTGRVFSSPAPGLVMGVGNTGDHLKKYSEGSLYVSDDAGVTWRHALDGPFKYEFGDQGSVIMAVSDKGTTDEIQFSIDHGKEWHSTKLQHKIYPKLLTTTPDSTSLTFLLVGSEESSGTKHVVYSIDFRGLHERKCEKDDFEKWAARLNENGEPDCLMGHQQFFNRRKANADCFVDEEFKDPQPIFEPCKCSFEDFECDFNFVRSEDGKSCVPAAPLVPPVGRCQKQTDTFMGPSGWRLIPGNTCTREGGENLDKDVERPCKDVVSAPSHDKLMAQKQVFNDARQFSEQYYYLERQASSSGDDETVIMLTSEGEFWVSHDHGKNWEQPLKGVKIAAIVPHPYYSDGAFLLTRDKQAFWTVDRAYTFKSFEAPIPPNQEGLPVLSFHPQYKDWLIWTGAVDCAHGDCHSDAYFSKNRGENWDLLLRYVGKCEFESRENRPGSEKLIFCQQYENENKKNHLQLLSSENLFSDSHVHFNDAIRYATMSEYIIVASRDPDNPDSLVASVSVDGRTFARAEFPPNVDVPVKTAFTVLDSSTHAVFLHVTVSDVKGAEHGSIIKSNSNGTSYVLSLNAASRNEWGYVDFEKMQGLEGVAVVNIISNVEAVLKKGPTAKKLKTMITHNDGGQWMLLPPPAKDADGKNFGCSVKGGKGSGQCSLHLHGYTERRDPRDTFSSGSAIGLMMGIGNVGAHLSGKDEADTFMTRDGGITWKSVKKGRYMWEYGDSGSVIVIVPELRPTKVLYYSLDEGDNWEPYEFSEVEMHIYRLSTVPSDTSKNFLLWGKEVESNRLATINVDFSGLRKKSCNLVENGQESDDYYLWEPKHPFQEDNCLFGHVEQYHRKKPSSQCWNNWREPHVHSIGRNCTCTRADYECNYNYEPQNDGSCALVPGLPKPDALAVCREDPDRVEYWEPTAYRRIPQTTCAGGLILDHVVSKPCPSKEKEYEKKHGISGTGLFFAIMIPIVAAAGVGYYVYAKWDGKFGQIRLGENAGTYEGLLSRESPIVTVPIAVIAGIVAVIRALPLLAMSLWRSASGYVRLGRNRAYSRPYASRGSFAARRGDYTSVVDDEDELLGVDDAEIDEDDEL
What is the function of this protein?
Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A.  Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment (By similarity).
What are the official names of this protein?
Vacuolar protein sorting/targeting protein 10, Carboxypeptidase Y receptor, CPY receptor, Sortilin vps10, Vacuolar carboxypeptidase sorting receptor vps10.
What is the protein family that this protein belongs to?
Belongs to the VPS10-related sortilin family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Prevacuolar compartment membrane; Multi-pass membrane protein. Note=Cycles between the Golgi apparatus and the prevacuolar compartment.
Protein: LEUD2_BORBR
Sequence: MQAFIRAHGIILPMNQDHVDTDAIIPQRWLVTVERDGLADGFMGAWRYDEHGQPRPECVLNQPAYQGAAIVLARENYGCGSSREHAVWAHQGYGIRAIVAASYGPIFHENCLKNGLLPVTLPAADVATLMAQALADPGCACEVDLVSQRVIGPDGRAYPFEIDAGRRQLLLEGVDDIDLALARAADIAAFQRRQQQDQPWLA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit 2, Alpha-IPM isomerase 2, IPMI 2, Isopropylmalate isomerase 2.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: DRS1_GIBZE
Sequence: MAPSQKRKPADDFIFTIDDDDELPIEEEEVVAQPPKKKAKTAKKSKKSKRDASPEEDDDEDAVEGIWGFNDDDDGAMDSDFEFGGDETANDNGVEDFEGWGFEGAKKGMRVEKAGVDLDEIIRRRREKKLGKSTENATAEEKADDAEAETMDVDLDDDDDEVLADDAFGMNVASDAEESGDEKEEDDEEEQESGVEVEDDDEAASDNDSVATPTNHPDDDASDASDDEEDAEEEAKRKAFFAPEEENNPDKKATASSFQTMSLSRPIMRGLASVGFTKPTPIQAKSIPIALMGKDVVGGAETGSGKTGAFILPILERLLYRPKKIPTTRVVVLLPTRELAIQCHAVATKLAAFTDIKFTLAVGGLSLKAQELELKLRPDVIIATPGRFIDHMRNSASFSVDTVEILVLDEADRMLEDGFADELNEILTTLPKSRQTMLFSATMTSSVDRLIQIGLNRPARVMVNSQKKTVTTLVQEFVRLRPGREDKRMGYLAHVCKNLYKERVIIFFRQKKDAHRARIIFGLLGLSCAELHGSMNQTQRISSVEDFRDGKVAYLLATDLASRGLDIKGVDTVINYEAPQSLDIYVHRVGRTARAGRKGVALTIAAESDRKVVKAAVKAGKAQGAKIVSRQLDSGEVDALQTQIDEMDDEIDEIMEEEKEEKQLAHVEMQVKKGENMIQHEAEIKGRPRRTWFESEHDKKKSKQAGRDELNGMREEMKKKTGKLSNKDKKRLDLKQLRAEGGGEWRKGKNSEAEMKARHKEAKAKSQAKKAGDKGSAPKSKGKPKGKGVLCLIREP
What is the function of this protein?
ATP-binding RNA helicase involved in ribosome assembly.
What are the official names of this protein?
ATP-dependent RNA helicase DRS1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX27/DRS1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: HEM3_PICTO
Sequence: MHIRIGTRSSKLAMIQAMMVKDRLDSLGIETEVKGFTSKGDINLDSPLYSIGGTGVFVDDLNRMILKNEIDIAVHSAKDIPSFIDDSLEISAVLKRDDPRDVLISQHSLNDLEASSVIGTSSLRRIKELKTLRNDILIKDLRGNIDTRLKKLDNGDYDGIIMAKAAYDRMRINRRHFILNYDDFVPAPNQGIIAIISKKDSEINDVLKKINDDETYNDMKAERLILSGLNLGCSKPVGIYAHKNRIFMRFYSLKNDDYKDIVMDYNNIDLEFIRSEIHDYGY
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Probable porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: PNP_SHESR
Sequence: MNPIVKSFEYGQHTVTLETGVIARQADAAVLASMGDTTVLVTVVGKKEAEAGRDFFPLTVNYQEKTYAAGKIPGGFFKREGRPSEDETLIARLIDRPIRPLFPNGFTNEVQVIITVVSVDPQIEPDIISMIGTSAALAISGIPFSGPLGAARVGYINGEYVLNPTVTQLANSQLNLVVAGTEGAVLMVESEAQALPEEVMLGSVVYGHDQQQVVIKAIAEFKAEAGKPAWNWTAPVANEALVAQVKELAEAGLAQAYQIQVKQERYAQVAVVKAAAKEALLAANPEVDLREVDGLLGSLEKKVVRGRIIRGEPRIDGREPDMVRALSVLAGVLPRTHGSALFTRGETQALVTCTLGTERDAQKIDSIMGERTNRFMLHYNFPPYSVGETGMVGSPKRREIGHGKLAWRGINAVMPTAEEFPYSVRVVSEITESNGSSSMASVCGTSLALMDAGVPIKTSVAGIAMGLVKEGDNFVVLSDILGDEDHLGDMDFKVAGTRDGVTALQMDIKIEGITKEIMEIALQQAYGARVHILNVMDQAIGSHRDDISDHAPRITTIKINPEKIRDVIGKGGAVIRALTEETGTTIELEDDGTVKIASSNGEATKEAIRRIEEITSEVEVGRIYNGKVIRIVDFGAFVNILPGKDGLVHISQISDERVANVSDHLELNQEVTVKVMEVDRQGRVRLSIKEAQTKEAAAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSB_BRUSU
Sequence: MAGSVNKVILVGNLGADPEIRRLNSGDMVANLRIATSESWRDRQTGERKDRTEWHSVVIFNENLAKVAEQYLKKGAKVYIEGALQTRKWQDQNGNDRYSTEIVLQKFRGELQMLDSRSEGGEGRSFGGGGNRNQMSDYSGGGGDFGSSGPSSGSSGGFSRDLDDEIPF
What is the function of this protein?
Plays an important role in DNA replication, recombination and repair.  Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
What are the official names of this protein?
Single-stranded DNA-binding protein, SSB.
Protein: LGSN_CANLF
Sequence: MNDEGDLLQENTRDEGNETEASRMSKLRRTRKKVTKQHIFSTEVGEMDVSNSKERIRSQMVCHTLGNMSKPVVGPGSADSHLPQDDKDSENQTTVIKPSPLKTSASAPCSEFNTNSNHADNTWEDTQIPTTPHLSSRMKHIKQEMAKNHLQFVRFEATDLHGVSRSKSIPAHFFQEKVIHGVCMPRGYLELIPNPKDDEVDHIRATCFNSDIVLMPELSTFRVLPWAERTARVICDTFTVTGEPLLTSPRYIAKRQLSQLQDSGFSLLSAFIYDFCIFAVPEIINSKTISFPASTLLNNHDQPFIQELVDGLYHTGANVESFSSSTRPGQMEICFLPEFGISSADNAFTLRTGVKEVARKYNYIASFFIETGFCNSGILSHSLWDVDGKKNMFCSSSGIEELTITGKKWLAGLLKHSAALSCLMAPAVSCRKRYSKESKDLKESVPTTWGYNDNSCAFNIKCHGEKGTRIENKLGSATANPYLVLAATVAAGLDGLQSSDGVLASPGDSTDLYPSKPSEIPLKLEDALVALEEDQCLRQALGETFIRYFVAMKKYDLENEETDAERNKFLEYFI
What is the function of this protein?
May act as a component of the cytoskeleton or as a chaperone for the reorganization of intermediate filament proteins during terminal differentiation in the lens.  Does not seem to have enzymatic activity (By similarity).
What are the official names of this protein?
Lengsin, Glutamate-ammonia ligase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
Protein: TBG_COCH5
Sequence: MPREIITLQAGQCGNSVGQQFWQQLCQEHGINKDGNLEDFATEGGDRKDVFFYQSDDTRYIPRAILLDLEPRVLHSIQASPYKNIYNPENFYIHKDGTGAGNNWGMGYSMGEQVHEDILDMIDREADGSDSLEGFMMLHSIAGGTGSGLGSYMLERLNDRFPKKLIQTYSVFPNTQDGDIVVQPYNSLLSMRRLTQNADSVVVLDNGALTRIAADRLHVMNPSFEQTNQLVSTVMSASTTTLRYPGYMHNDLVGIVASLIPTPRCHFLMTSYTPFSGENVEQAKTVRKTTVLDVMRRLLQPKNRMVSTNPTKKSCYMSILNIIQGEADPSDVHKSLMRIRERRLATFIPWGPASIQVALTKKSPYVTSSHRVSGLMLANHTGIATLFKRIVAQYSTLRKRNAFLESYKREVPFKDGLGEFDEAKEVVQGLIAEYEEAEDADYLTKETAPTDEAEDKRAG
What is the function of this protein?
Tubulin is the major constituent of microtubules.  The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly (By similarity).
What are the official names of this protein?
Tubulin gamma chain, Gamma-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body.
Protein: NU6M_XENLA
Sequence: MIYMVSVSMMVLVLGLVAVASNPSPFYAALGLVLAAGAGCLVIVSFGSSFLSIVLFLIYLGGMLVVFAYSAARAKPYPEAWGSWSVVFYVLVYLIGVLVWYLFLGGVEVDGMNKSSELGSYVMRGDWVGVALMYSCWWVIIVYWWVSIIINFVCGIWVNSKSMWWESSCV
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MNMG_DESVH
Sequence: MSTIRKPSPPDMYDCIVVGAGHAGCEAAMALARMGHATLLLTGNADRIGHLSCNPAIGGLAKGHMVKEIDALGGMMGLWADEAGIQFRTLNSSKGPAVRATRAQIDRDAYLRVVRRDIFAQPNLRVWQDMAESIIVEEGRAAGVRTAYGQEFRAHHVLLTTGTFLQGRIHVGLSNFPGGRLGDAPATGLSASLRAIGLELGRLKTGTTPRLLRDSIDFSMMEVQPPDDPPRPFSFRGPGVRLPQLPCHVTWTNERTHEAIRAGFDRSPMFTGVIKGTGARYCPSIEDKVARFPEKERHQVFVEPEGLESPECYPNGIPTSLPLEVQKAMIATIPGLENAQIVRPGYAIEYDYADPVQLRSTLETKALRGLWLAGQINGTSGYEEAAAQGLWAALNVSCTLRSMPPFLPGRDTAYMAVLVDDLVTKGTREPYRMFTSRAEHRLLLRENNADARLTETGRALGLVDDTHWQLFSTKRAALHSLLDELENRRITPDAAARDIFSRLGEPAPTKGVSLADILRRPSLTLPDLAPFWEGVTRFADDVREEAETIVKYSGYLARQQELVARSARMEDTVLPEDMDYTVIPGLTREIVEKLGKVRPHTLGQAARISGVTPAALTCLEIQLRKMGQR
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRCB_NITOC
Sequence: MWQKLAWIALAGAGGTLSRYALSGLVQNLCGASFPWGTWVVNGLGCFLFGMIWALAEERLLITGEIRFIVLTGFMGAFTTFSTFAFEASQFLRDSEWLLAAIHLIGQNSLGLVCVFLGFTISQII
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RSMH_SHEAM
Sequence: MSQDFAHLSVLLAETVDGLNIRADGIYIDGTFGRGGHSREVLSRLGVDGRLIAIDRDPQAIKAAEQFANDSRFQIVHGGFGQLANYVEELGLVGKIDGVLLDLGVSSPQLDDAERGFSFLRDGPLDMRMDNSQGETAAQWLARAEIEDMAWVFKTYGEERNARHIARCIAADREKTPFTRTKQLADLIARVAKSKERNKHPATRVFQAIRIYINSELEQIDQALEGALKVLAPHGRLSIISFHSLEDRIVKRFIRRHSQGEELPHGLPVTEAQLNKSRTLMPVGKAMKPSDVEIEQNARARSSVLRVAERLPF
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HAS1_PICST
Sequence: MAKNVNSKANGKKSGSVKRALKEKKQPEPEFSDSEDDEVDQEKLVEELDEDFDEVANMLGADVTDPEEKKQSKLERKRKRDEEATAEYTKPEVVDNEDDAQNDKFEDAGLSEPTMRAISDMGFKTMTKVQAKTIPPLLAGKDVLGAAKTGSGKTLAFLIPAIELLYSLKFKPRNGTGVIVVSPTRELALQIFGVARELMAHHTQTFGIVIGGANRRQEAEKLAKGVNLLIATPGRLLDHLQNTQGFVFKNLKALVIDEADRILEIGFEEEMKQIIKILPKEERQSMLFSATQTTKVEDLARISLRPGPLYINVVPETAASTADGLEQGYVVCDSDKRFLLLFSFLKKYSKKKIIVFLSSCNSVKYFGELLNYIDLPVLDLHGKQKQQKRTNTFFEFCNAKQGTLVCTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGSNGKGKSLMFLTPSELGFLRYLKAANVPLNEYEFPTNKIVNIQSQLSKLIKSNYWLHQSAKDGYRSYLQAYASHHLKTVYQIDKLDLVKVAKSFGFDVPPKVNITIGASGKSIEKKHKKQKRA
What is the function of this protein?
ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis.  Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.
What are the official names of this protein?
ATP-dependent RNA helicase HAS1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: CYOE2_PSET1
Sequence: MALTIDKKAIQPINTLPLITRSYNLLQDYLAISKFKVVAMLVLTAWVGLALAPDVGRGMGVQFISLLGIGLLSAAAAVINHVVDSEIDSKMARTRHRPVAKGRLSKAHALSFAAIIGVAGFIMLMLWANTLTAILTLFALVGYAFVYTSFLKRATPQNIVIGGLAGAMPPLLGWVSETGQMAAAPWLLVMIIFTWTPPHFWALAIARKSDYARAKIPMLPVTHGIDFSKTCVVAYSVLLAIVCIFPYLIGMSGLIYLIGASGLNAVFIYKAIKLKLAANDDTAMDLFRFSIIHLMVLFIILFIDKWLLL
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase 2, Heme B farnesyltransferase 2, Heme O synthase 2.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYN1L_BOVIN
Sequence: MESLSELQNPLLPRSPTHLHGPYPYPEASPAWPCREKIYSYLLGGAGPAHAHQLLDPGSLQLAVEAWYRPSCLLGRDKVKEPRPGSCETSFTEGREPPAGPTERSTEPGQAEEDVAIQTVSYGVQEEFQGQEGDPEEEESDATSTESESEDNFLTLPPRDHLGLTIFSMLCCFWPLGIAAFYFSQGTSKAISKGDFRLANTTSRRALFLATLSIAVGAGLYVAVVVALAAYMSQNGHS
What are the official names of this protein?
Synapse differentiation-inducing gene protein 1-like, Capucin, Dispanin subfamily C member 1, DSPC1, Transmembrane protein 90A.
What is the protein family that this protein belongs to?
Belongs to the CD225/Dispanin family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Golgi apparatus, cis-Golgi network.
Protein: AKT3_RAT
Sequence: MSDVTIVKEDWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQLMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCSPTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDPKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDEEFTAQTITITPPEKDDDDGMDCMDNERRPHFPQFSYSASGRE
What is the function of this protein?
AKT3 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis.  This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates.  Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported.  AKT3 is the least studied AKT isoform.  It plays an important role in brain development and is crucial for the viability of malignant glioma cells.  AKT3 isoform may also be the key molecule in up-regulation and down-regulation of MMP13 via IL13.  Required for the coordination of mitochondrial biogenesis with growth factor-induced increases in cellular energy demands.  Down-regulation by RNA interference reduces the expression of the phosphorylated form of BAD, resulting in the induction of caspase-dependent apoptosis (By similarity).
What are the official names of this protein?
RAC-gamma serine/threonine-protein kinase, Protein kinase Akt-3, Protein kinase B gamma, PKB gamma, RAC-PK-gamma.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Membrane; Peripheral membrane protein. Note=Membrane-associated after cell stimulation leading to its translocation.
Protein: IF1_STRPC
Sequence: MAKEDVIEIEGKVVETMPNAMFTVELENGHQILATVSGKIRKNYIRILVGDRVTVEMSPYDLTRGRITYRFK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HCP_VIBPA
Sequence: MFCIQCEQTIQTPAVKGCSFAQGMCGKTSEVSDLQDVLVYTLQGVSFWASKALEFNIINDEINQWAPKAFFSTLTNVNFDPERILELTSQAANYKALLKEQVMSAATLSNTNLADIPAVANFELPNSAEAILAFAPQVAVNRGKDQVHEDVIGLRLLCLYGLKGAAAYMEHARVLEQTNNDIYAEYHEIMAWLGTDPEDLGELLDCSMRIGLMNYKVMEMLDQGETTTFGHPEPTTVNVKPVKGKCILVSGHDLHDLEKILQQTEGKGINVYTNGEMLPAHGYPELKKYPHLVGNYGSAWQNQQKEFANFPGAIVMTSNCLLNPNVGQYADRLFTRSIVGWPGVAHIEGDDFSQVIECALAQDGFQHDEIEHHITVGFSRNALMNAAPAVIDQVKQGNIKHFFLVGGCDGDKAERSYYTDFTAEAPEDTLILTLACGKFRFNKNTFGDINGIPRLLDVGQCNDAYSAIQLALALAKEFDCDINELPLTLVLSWFEQKAIVILLTLFALGVKGIYTGPTAPAFLTPNLIAIIQEKFDMRSIGNVQDDLKAILAA
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA1_HALH5
Sequence: MNIGRIVTAMVTPFNEQDQVNLEATCQLVNELIANGSDALVVGGTTGESPTLTTDEKMALFHTVVEAAGGRVPVIAGTGSNNTRASIELSKKVEDLGVDGIMLVTPYYNKPSQEGLFQHFKAISESTSLPIMLYNIPGRSGVNLDAETTLRLAELRNIVSIKEASGNLDQIAEIIEHSPADFSVYSGDDSLTLPLLSIGGTGVVSVASHIIGNEMQEMVQLFLSGQVERAAAIHRKLLPLMKTLFMTPNPTAVKAALELKGLPVGHVRLPLVPLTAEEQRQLELAINPQFNMFVS
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase 1, HTPA synthase 1.
What is the protein family that this protein belongs to?
Belongs to the DapA family.