PharMolix/UniProtQA huggingface dataset:
Protein: Y6689_DICDI
Sequence: MKLSESTINKDYPFLSEEEDSKIISLICNYLSLGQFELARALILQSQEKQQLKNQQKQTQSDNNNNNNNNNNNNNNNNNNNNCDRISSILYHTIRNGPPSTWLTSESIPSSPHLSWLCSIEFYQLNKDGFISSISEKTLLLVEFAILIYTLLGEQQNNDSRNIQPIIQELREYHYVLLSQQRQQSNNKNNNNNNIDNLSEQQIYQMESILLRSKLGNSTISILKTILINNTEFGRYIIKQFTNPFISSLNNNNNNNGISNSLLYSRYPVTQQLESLVAEVITLLIDSSQYNEAYNLLSIIDISNNDNSNSNNNNNNNNNNINSDEVDSNSGDNNIISKLLERVANLNNSNFGNNVEELTLLKIPFSSKLSNLETDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGKSISRLKIYESLLSNPTLTPLKTYLKHEESILKENSSQQQPIDFPECFEILKNYFSLKPKQLDINSKNNNNDNNNNNNNNSSSSGSNSSSSRNKNNLKNNLKSFDRKDSEYQNAESIFWYWYYHFLRVNDRHYLEYALEKSIDLIKNKRFEEALIVVKPFEKLLPLLILLCWDHFENDITSRKHLTNLLDLSKGISKFNKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEWSCRRMIAVPNSPNGHSLIIGESTFDLLDEKSKTLRGSFSPSSMSPSIPPSASNDSSLTSSPYLLSLGRSMTTNISNAILSQLFHHSFIYVVKDCLPFITSNDILKFIEKDPDFPINYQQQQEQQEQQQQSNDSENLLSQIALDKLNDMNLVRGYYLIKNILKFFQYRATSTDAIVDKVEFDSVLDDVFDLFKGISNANISIGLIESLYLSLFLSNQDLKSNNNNTNDLGEISSSSSAFRLNNDFNYNNNSNNNDKPNNNEFYQYYKKVISNSSEENNLSYYLVNNNSHNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNEINEQIIEIIDNEFSYQKLSKSQHKQYYITCVMLESLINKLITLIDFIVDSSLQQQQKQEIKKERIQILLLNLENLKHRVDLSKWILNLDDNNYNHIPFMSLVLMPIKSLILMAMRTNYPNFQIIIKYFDIPKDIENQAYQFKSIPDLLDVLENNGGGDNDDDGADINLNQLTTSFNGINNDNIFQILSDIVIGSNCNNSLIKKILKINNNNNNDNDNNNKSKSYLNWISILHKEYIDQISTTNSNSLYDILINPQSIPDKDYQNISKMKQYINNKKIIIKSLNRLIKCYDNTINNKNNNNNIDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIEDDVKIIIENDNNISNNQILSTLFKYILSVNQIYSNCSDYSSIFRNINQSPKSILQDIVFNEKDYKKAEQLSNLLQVDLSDLIISSISHTTPKNPPSSLFKSSTPESSVLNSPIFYINNQQQQQQQLQLQQQQQQQQLQQQQQQQQQLQLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQLTNDNIQKNYLTMDLVNYFDKSSKLLSSLVCMLKSPDHKDVEPFIQFSIENSKKLPSNSFSNWINEILKAHTFYHKYFNQQQNNNYNNNNYNNNYNNNNNNNNNNNNNNNNNNNIDNQQTINETFDYKLIQNSESIHQQQNFFFKIIQFFVNNNNLMDALKIADEYLEEGAPDWLLKLLVFKDRSQGYKYIRRMRDKPKALNLVLELYNNWDIATCIDMIVICKSFLGLPDQINQQQQPTTTTTTTIQDQQDENIKNELNHLHKAFLLYQSILNNANNGNVYRNWQEIKEICQNDPATMVRNLLDSKHYDLARKIRDHFSVSGIKKEIEERYLYYLLVEKDDASLALQTLSELGEESISILDSLLPVINEISVKLFLVQFLLSNMRSKLSKEKLEELTKQEIGYQVLLVLPTDLQVEYSQFINHPLLIIEMLIMNEKIPLVAKLLLDIKELKDVDDLLTYYARKALSFSRYLAKNDLMMLDDYLQKEFNDQDDYVSNNNYNKNDQINSKEKDKDKKRKSFLSNLPIITNKSSQTIKQSPSFEVEDFRHEISNRSSTPPPPPPTETPSLNIVHSTSPNSSVSLLKDKNIQQKWLLTGNDTVQDEKIRHSHFFIRSPSISLAKSLFDLCESKKKVYNTCIELYSNLSMLLSSNYSDDNLLIINLIQQLLMYTKLQLLRDPKSGGPTLVAVCDTYLGKVELFQSLVVSKCSGSMSLVDLSDPQKARQLRDRLIQEDRLRLAIDVATKCNIPADSAWVSWGISLIQTGSYSEAREKFKYCLTPTGPDRRVMSPSNSLSIDTIDSGVILNQIIQLLESPPSPNHSNFRSLYNYLLSTQGGGSSSNLKSTPKIDDSMFYNLLQPQLLNNSSNNSNNNNNTNNNNNNNNAITNLFSNAFSDKKSLTNNNSSSINNTTIINNIEMDKNRLDEAIYYLKKYGNGRMLVNFLIKHNLYELACKTILSDSLSFNIFYDEIVLKAIANSSLQDLFNTIKSIDPKLLAFQDHLLASCKNMNERKQYQLLFEFQLYMGDNVRAGLTCVKMFLTNPEGTANSRVHHLEQALYYFNIGLTNYVKGCVLSQPEINNYIQNCTTQLEISKFFYKSSSVFPTTSPVHKLSIFGTIKQKTELVEQLTINGNFDLGFKIAQESKLTLPPIYVNALTTMARKKMSSKIEDYLNQLRGCINPEDWELIAMPVFETQCLELKEFKSAEKFIPKLYTVYNSVRISILCGKLKTAYLTAVQHKDRSLIKMVMDEAQKTNQPVIFKWCQEILNQ
What are the official names of this protein?
Protein DDB_G0276689.
Protein: YCF20_AGLNE
Sequence: MQFILYIIGQYLYYHINNLSLQLISLFLGYFFCTIICSIPKETGDWGLITALLIVGINETMSALIYSYKKYENNIIVKTINGIKIGIIYGLFVDSFKLGS
What are the official names of this protein?
Uncharacterized protein ycf20.
What is the protein family that this protein belongs to?
Belongs to the ycf20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL31_BAUCH
Sequence: MQKNIHPKYFEIRAICSCGNIIPTYSTLDQHLNLDVCSACHPFYTGKQRRVNTRGRVERFNKRFSLSIMNSKKKE
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: PSBK_NYMAL
Sequence: MPNIFSLICICLNSALQPSGFFFAKLPEAYAFLNPIVDFMPVIPVLFFLLAFVWQAAVSFR
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein K, PSII-K.
What is the protein family that this protein belongs to?
Belongs to the PsbK family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CASP1_WHEAT
Sequence: MSTSEAATVIPVYDVAPGQGAPSKAPAAAPPSAAAAAPAAAATTTAPRKFPMRFFRRSDRGSRCMAFLDFLLRIAAFGPALAAAIATGTSDETLSVFTEFFQFRARFDEFPAFLFLMVASAIAAGYLLLSLPFSAVVVLRPQTTVLRLLLLVCDTIMLGLLTAGAAAAAAIVDLAHSGNERANWVPICMQFHGFCRRTSGAVVASFLSVFIFVLLVVLAAFSIRKR
What is the function of this protein?
Regulates membrane-cell wall junctions and localized cell wall deposition.  Required for establishment of the Casparian strip membrane domain (CSD) and the subsequent formation of Casparian strips, a cell wall modification of the root endodermis that determines an apoplastic barrier between the intraorganismal apoplasm and the extraorganismal apoplasm and prevents lateral diffusion (By similarity).
What are the official names of this protein?
Casparian strip membrane protein 1, TaCASP1, Salt tolerance protein, TaSTG.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Very restricted localization following a belt shape within the plasma membrane which coincides with the position of the Casparian strip membrane domain in the root endodermis.
Protein: GMFB_RAT
Sequence: MSESLVVCDVAEDLVEKLRKFRFRKETHNAAIIMKIDKDKRLVVLDEELEGVSPDELKDELPERQPRFIVYSYKYQHDDGRVSYPLCFIFSSPLGCKPEQQMMYAGSKNKLVQTAELTKVFEIRNTEDLTEEWLREKLGFFH
What is the function of this protein?
This protein causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells.
What are the official names of this protein?
Glia maturation factor beta, GMF-beta.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family. GMF subfamily.
Protein: SYGB_ACTSZ
Sequence: MTTENFFAEIGTEELPPKALKKLATAFAENVENELKQAGLAFDKVEWFAAPRRLAVKVLNLAANQPSKEIEKRGPAVSAAFDAEGKPTKAAEGWARGCGITVDQAERLVTDKGEWLVHRAVIEGQPTKNLMLDIIAKSLANLPIPKTMRWGDKNVQFVRPVHTVTLLLGGELIEGEILGIASGRTIRGHRFLGEREFQISHADQYPSLLEEKGCVIADFNKRREMILTKSQEKATALGGVADIEDDLLDEVTSLVEFPNVLTAKFEERFLAVPAEALVYTMKGDQKYFPIYDKEGKLLPHFIFVSNINPVDPMPIIEGNEKVVRPRLSDAEFFFNTDKKQRLEDLLPRLQTVLFQQQLGTLLDKTKRIQSLAGEIAGQIGADKAKAERAGLLSKCDLMTNMVFEFTDTQGVMGMHYARHDGEDEEVAVALNEQYMPRFAGDNLPNSLVASSVALADKFDTLTGIFGIGQAPKGSADPFALRRAALGALRIIVEKNLSLDLADLVKKSAALFGDKLTNANVVDDVVDFMLGRFRAWYQDGGIAVDVIQAVLARRPTKPADFDARVRAVSHFRTLDSAEALAAANKRVSNILAKVAGEIRSEIDRTLLLEAEEKALAEQVLALQSELAPVFAKGDYQTALDRLACLREVVDNFFDKVMVNAEDEKLRQNRQAMLNVLRNLFLQVADISLLQ
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2024_NATTJ
Sequence: MRNENRFHEVRFVIITGMSGAGKSIVIQSFEDLGYFCVDNLPPTFIAKFAELIRQSEGRINKIALVSDIRGGQFFESLQSALYQLNELGIEYEILFLEADTTELINRFKETRRKHPLWNQYNSIKKAIEEERKELEVIRTQSHLIINTSNMSPRQLKDKIRRQYTPEGEYESNLFVSIISFGYKHGLPLDADLVFDVRFLPNPYYVDELRPLSGNDDSVEQYVLHFDATKQFLDKMEDMIQFLLPKYLKEGRTQLIIAVGCTGGRHRSVVISNWLKDKLLKTGYQIALQHRDLDK
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Nther_2024.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: NADK_ECO5E
Sequence: MNNHFKCIGIVGHPRHPTALTTHEMLYRWLCTKGYEVIVEQQIAHELQLKNVKTGTLAEIGQLADLAVVVGGDGNMLGATRTLARYDIKVIGINRGNLGFLTDLDPDNAQQQLADVLEGHYISEKRFLLEAQVCQQDCQKRISTAINEVVLHPGKVAHMIEFEVYIDEIFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINSSSTIRLRFSHRRNDLEISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYSYFNTLSTKLGWSKKLF
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_PARMW
Sequence: MGHKINPTGLRLGITQEHRSRWYASSKSYPALLQEDDRIRKFIHKKYGSAGISDVLIARKADQLEVELKTARPGVLVGRQGSGIEELRSGIQKTVGDRSRQVRINVVEVERVDGDAFLLAEYIAQQLEKRVAFRRTIRMAVQRAQRAGVLGLKIQVSGRLNGAEIARTEWTREGRVPLHTLRADIDYATKVASTTYGVLGIKVWVFKGEVLGDEAPLIPVGASPRRRASRRPQQFEDRSNEG
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: DXS_FRATF
Sequence: MSKYTILDKINTPSDLKLIPESQLKILSAELRAFLVDTLDVSGGHFASSLGATELTVALHYVYNAPYDNIVWDVGHQTYIHKILTGRKDKLVTIKKDGGISGFPKRSESEYDTFGVGHSSTSISAALGMAIADRLQGKSSNTVAVIGDGAITGGMAFEALNHAGGIKEDILVILNDNEMSISDNVGGLSAHFSKIISGGFYNSIREKGKEVLKNIPPIFEFVKKIETQTKGMFVPANFFEDLGFYYVGPIDGHDVTELVKTLRILKDHKGPKLLHVITKKGKGYTKAESDPIKFHHVAPSFHSGENITTKISKPTYSNIFGDWICQKAAKDKRLVGITPAMKEGSDLIRFSQLYPHRYFDVAIAEQHAVTFAGGLACQGLKPVVAIYSTFLQRAYDQVIHDIALQNLDVLYAVDRAGLVGADGATHDGSFDLAFMRCIPNHVIMTPSDENETYHMLEFGYEYNGPAMVRYPRGAGIGAEITGSLDLELGKAKIVKQGSKIAILNFGTLLPLAKQLAEKYHATVIDMRFVKPLDKIMLDKVSQTHEIILTLEENCIAGGAGSAVNEYFVAKDLSNKIIVRNFGLQDKFLNHGTKDLLLAQSKLCVENISKELDKLI
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: RL34_CLOBJ
Sequence: MFMTYQPKKRQRKKEHGFRKRMKTSSGRNILRKRRQKGRKRLTA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: H33_ARATH
Sequence: MARTKQTARKSTGGKAPRKQLATKAARKSAPTTGGVKKPHRYRPGTVALREIRKYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSHAVLALQEAAEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
What is the function of this protein?
Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes.  Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis.  Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.3, Histone H3.2.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Nucleus, nucleolus. Note=Localized at rDNA loci in the nucleolus.
Protein: IF5A1_RABIT
Sequence: MADDLDFETGDAGASATFPMQCSALRKNGFVVLKGRPCKIVEMSTSKTGKHGHAKVHLVGIDIFTGKKYEDICPSTHNMDVPNIKRNDFQLIGIQDGYLSLLQDSGEVREDLRLPEGDLGKEIEQKYDSGEEILITVLSAMTEEAAVAIKAMAK
What is the function of this protein?
mRNA-binding protein involved in translation elongation.  Has an important function at the level of mRNA turnover, probably acting downstream of decapping.  Critical for the efficient synthesis of peptide bonds between consecutive proline residues.  Can resolve ribosomal stalling caused by consecutive prolines during translation.  Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity.  With syntenin SDCBP, functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis.  Regulates also TNF-alpha-mediated apoptosis.  Mediates effects of polyamines on neuronal process extension and survival (By similarity).  May play an important role in brain development and function, and in skeletal muscle stem cell differentiation (By similarity).
What are the official names of this protein?
Eukaryotic translation initiation factor 5A-1, eIF-5A-1, eIF-5A1, Eukaryotic initiation factor 5A isoform 1, eIF-5A, eIF-4D.
What is the protein family that this protein belongs to?
Belongs to the eIF-5A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=Hypusine modification promotes the nuclear export and cytoplasmic localization and there was a dynamic shift in the localization from predominantly cytoplasmic to primarily nuclear under apoptotic inducing conditions. Nuclear export of hypusinated protein is mediated by XPO4.
Protein: CSPLS_ORYSJ
Sequence: MWEVAWWRPGTWGGLAMRVGQVAFAGASIGVMASGAGFANYTAFCYLIASMGLQSLWSLGLACLDVYALTVKRDLNNALLVSLFVIGDWVTALLSFAASCSAGGVMVLFKRDVLFCRRYPQLPCGRFELAVALAFLSWALSATSAIIMFCLLAAF
What are the official names of this protein?
CASP-like protein 5B2, OsCASPL5B2.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y538_VIBCM
Sequence: MVFVNSRHQGNHYEQMAADYLRRQGLTLVTQNVNYRFGELDLIMRDGNTLVFVEVRYRNNTQHGHAAETVTRTKRARLIKAANCWMLANKMNSHSADFRFDVIAIHQQGQHIDWLKNAITEG
What are the official names of this protein?
UPF0102 protein VCM66_0538.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: PGK_SHEON
Sequence: MAIINMSDLDLQGKRVLIREDLNVPVSNGVVTSDARLRASLPTIELALAKGAAVMVMSHLGRPTEGEYNSEFSMQPVVDYLAKALSCPVRLATDYLDGVEVAVGEVVVFENVRFNKGEKKNDEALSKKMAALCDVYVMDAFGTAHRAEASTNGVGLYAPIACAGPLLAQELDALGKALDNPARPLVAIVGGSKVSTKLTVLESLSGIVDQLVVGGGIANTFIAAAGHNVGKSLYEADLIDEAKRLVANAQSRGGDIPVPTDVVVAGEFSPTAAATLKAVSDVGDSDMIFDIGPDSAEALAKIIESAGTIVWNGPVGVFEFDQFGEGTKRIAHAIADSKAFSIAGGGDTLAAVDKYGIADKVSYISTGGGAFLEFLEGKELPAVAMLKKRGA
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARC_ACTMD
Sequence: MPHGHPGSQPDEGGELSNGSSSGELTAQIRFLEDEIALLRRKLTESPRHARLLEQRLAEATERVNQLTERNTKLIDTLREARGQLLALREEVDRLAQPPSGYGVFLARFEDGTVDVFTSGRRMRVSVSPSVETSSLVMGQSVRLNEALTVVEGGDFERTGEVCALREVLDDGGPEGSVARALVVGHADEERVVWLAQPLLDSPLKAGDSLLVDSKAGFAYERVPKAEVEDLVLEEVPDVRYEDIGGLSRQIEQIRDAVELPFLHADLFREYKLRPPKGVLLYGPPGCGKTLIAKAVANSLAKQVSKARGEDHKDAKSFFLNIKGPELLNKFVGETERHIRLIFQRAREKASEGTPVIVFFDEMDSIFRTRGSGVSSDVETTIVPQLLSEIDGVEGLENVIVIGASNREDMIDPAILRPGRLDVKIKIERPDAEGAKDIFAKYLTDDLPLHADDLTEFGGDPAACIQGMVQHTVERMYEETDENRFLEVTYANGDKEVLYFRDFNSGAMIQNIVDRAKKSAIKSLLDTKQPGLSVRHLMDAIVDEFAENEDLPNTTNPDDWARISGKKGERIVYIRTLVTGKNQETGRAIDTATNTGQYL
What is the function of this protein?
ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle.  May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis.  Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
What are the official names of this protein?
Proteasome-associated ATPase, AAA ATPase forming ring-shaped complexes, ARC, Proteasomal ATPase.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
Protein: RS14Z_CAMFF
Sequence: MAKKSMIAKAARKPKFSARGYTRCQICGRPHSVYKDFGICRVCLRKMANEGLIPGLKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: SIDI_ASPFU
Sequence: MATIRRLQQTLSHLRPPKAPQLLSIVEGPTQPELLDITLGELLTLQSLQYGDYECLVFPWTGARWTYTDLKDEADRVARGLLAMGIQKGDRIGIMAGNCEQYISVFFAAARVGAILVVLNNTYTPSELYYALGHTDCRLLFLTPRIGRHSLEEVLAKLGPRPKEQGTSSALEEIIILRGQYSGFSTYEHVIQRGLPLPSHALQDREAELHSTDVCNLQFTSGSTGNPKAAMLTHHNLVNNSRFIGDRMNLTSFDILCCPPPLFHCFGLVLGMLAVVTHGSKIIFPSETFDPTAVLHAISDEKCTALHGVPTMFEAILSLPKPPNFDCSNLRTGIIAGAPVPRPLMKRLLEELNMTEYTSSYGLTEASPTCFNALTTDSIERRLTTVGKVMPHAKAKIIDTQGHIVPIGQRGELCIAGYQLTKGYWNNPEKTAEALITDSDGVTWLKTGDEAIFDEEGYCSITGRFKDIIIRGGENIYPLEIEERLAAHPAIEVASVIGIPDQKYGEVVGAFLALAADVSARPSDEELRAWTRETLGRHKAPQYFFVFGEEGVDRTIPVTGSGKVRKVDLRKIAASVLERRLAKTAAIKEK
What is the function of this protein?
Acyl-CoA ligase; part of the siderophore biosynthetic pathway (PubMed:22106303).  Aspergillus fumigatus produces 4 types of siderophores, low-molecular-mass iron chelators, including excreted fusarinine C (FsC) and triacetylfusarinine C (TAFC) for iron uptake and intacellular ferricrocin (FC) for hyphal and hydroxyferricrocin (HFC) for conidial iron distribution and storage.  TAFC consists of 3 N(2)-acetyl-N(5)-anhydromevalonyl-N(5)-hydroxyornithine residues cyclically linked by ester bonds; FC is a cyclic hexapeptide with the structure Gly-Ser-Gly-(N(5)-acetyl-N(5)-hydroxyornithine)x3.  The biosynthesis of all four siderophores depends on the hydroxylation of ornithine, catalyzed by the monooxygenase sidA (PubMed:15504822, PubMed:16113265).  Subsequently, the pathways for biosynthesis of extra- and intracellular siderophores split (PubMed:17845073).  For biosynthesis of extracellular siderophores, the transacylase sidF transfers anhydromevalonyl to N(5)-hydroxyornithine (PubMed:17845073).  The required anhydromevalonyl-CoA moiety is derived from mevalonate by CoA ligation and dehydration catalyzed by sidI and sidH respectively (PubMed:22106303).  The acetylation of N(5)-hydroxyornithine for FC biosynthesis involves the constitutively expressed sidL (PubMed:21622789).  FC is hydroxylated to HFC by an as yet uncharacterized enzyme during conidiation (PubMed:17845073).  Assembly of fusarinine C (FsC) and FC is catalyzed by two different nonribosomal peptide synthetases (NRPS), sidD and sidC respectively (PubMed:17845073).  Subsequently, sidG catalyzes N2-acetylation of FsC for forming TAFC (PubMed:17845073).  Both extra- and intracellular siderophores are crucial for growth during iron limitation and virulence (PubMed:16113265).
What are the official names of this protein?
Acyl-CoA ligase sidI, Siderophore biosynthesis protein I.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Peroxisome. Note=Targeted to peroxisomes via its PTS2-type peroxisomal targeting signal and the corresponding receptor pexG (PubMed:23617799).
Protein: TACA1_TACTR
Sequence: YSRCQLQGFNCVVRSYGLPTIPCCRGLTCRSYFPGSTYGRCQRF
What is the function of this protein?
Exhibits stronger antimicrobial activity against the Gram-positive bacteria (S. aureus (IC(50) is 4. 2 ug/ml)) and fungi (C. albicans (IC(50) is 3. 0 ug/ml) and P. pastoris (IC(50) is 0. 5 ug/ml)) than Gram-negative bacteria (E. coli (IC(50) is 25 ug/ml)).  Binds to chitin (8. 4 uM are required to obtain 50% of binding).  Does not cause hemolysis on sheep erythrocytes.  Has no blocking activity on the P-type calcium channel.
What are the official names of this protein?
Tachystatin-A1.
What are the subcellular locations of this protein?
Secreted.
Protein: FEOC_KLEP3
Sequence: MASLMEVRDMLALQGRMEAKQLSARLRTPQPLIDAMLERMEAMGKVVRISETSEGCLSGSCKSCPEGKAACQQEWWALR
What is the function of this protein?
May function as a transcriptional regulator that controls feoABC expression.
What are the official names of this protein?
Probable [Fe-S]-dependent transcriptional repressor.
What is the protein family that this protein belongs to?
Belongs to the FeoC family.
Protein: UPP_MOUSE
Sequence: MASELQRPDSMPCHNRQVNSTSSPSPEHLLAEDRVLDHAEENNAAMAKLTLLPGHAHSSVLSERDSPACCSTNLHSENHSDSSDSGNYDAPVGGDSLLGDCELSRQIGAQLKLLPMNDQIRELQTIIRDKTASRGDFMFSADRLIRLVVEEGLNQLPYKECMVTTPTGHKYEGVKFEKGNCGVSIMRSGEAMEQGLRDCCRSIRIGKILIQSDEETQRAKVYYAKFPPDIHRRKVLLMYPILSTGNTVIEAVKVLIEHGVQPSVIILLSLFSTPHGAKSIIQEFPEITILTTEVHPVAPTHFGQKYFGTD
What are the official names of this protein?
Uracil phosphoribosyltransferase homolog.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RECX_BACC4
Sequence: MAVITKIEVQKRSKERFNIYIDKGQGEEYGFSVDQVILIKHGLQKGLEIDEIELGNILYNEEVQKAYLQAISYLSYQMRTKQEIEDFLRKKEVGQAIISEVVSKLLHDRYINDKEYAVLYTRTQSNVNRKGPTVIKRELLNKGVQDLIITHSLQEYPKEKQIENALFLIEKKKKSYQKHSFLQMKLKLDEMLVRKGYSREVIQICLEELKDEKDDEKQQEALHYHGNKYYEKYKKHDGWTFENKMKQALYRKGFSIDEIEIFLQMKREEE
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_SACD2
Sequence: MTVESTAAPAKVNLMGLSQAKLEAFFDSLGEKRFRATQVLKWIHQMGVTDFEQMTNISKPLRDKLSQVAEAVAPEVVNQWDSSDGTRKFLIRVGGGNAVETVYIPDGDRGTLCVSSQVGCSLDCSFCATGKQGFNRDLTAAEIIGQVWQAAKSFNQFGVGAQRKITNVVMMGMGEPLLNFDNVVDSMNLMMHDNCYGLSKRRVTLSTSGVVPALDKLGEYTDACLAISLHAPNNALRNELVPINKKYPIEMLLASAKRYIDGLPDVRRKMTIEYTLIDQVNDRPEHAHELAELLKDIPVKINLIPFNPFNLSNYKRVSNNALRRFQQILIDAGYTTTVRTTRGDDIDAACGQLAGQVNDRTKRSQRYKIDKNALDASNADIIPVKLVDEADVSITFNG
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOAC_RHOCA
Sequence: MVDVSDKVETKRTAVAEGRVVMRPETLALVIAGRAGKGDVLGIARVAGIMAAKRTADPKNSKSFSRVLLERPRAHSI
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.