PharMolix/UniProtQA huggingface dataset:
Protein: TRUA_EHRCJ
Sequence: MRYKITIEYNGSNFIGWQRQKHLSNSIQEILEEAIFKFSRESVTTYVAGRTDAGVHALGQVAHFDLTADFDAYVVRNAINYHLIPHSISVLNVEKTDDEFHARFSAKKRHYLYKIINRYSPLTIDYNRAWLVRNPLDVEKMMRAVEYIKGNHDFSSFRARHCQSKSPVKTMDDLKIIHSDQCIDIYFSAISFLHNQVRIIVGTLVECGKNSFPPEYTKDILEAKDRSYAGMTAPPYGLYFVKVDY
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: CAS1_THEMA
Sequence: MESVYLFSSGTLKRKANTICLETESGRKYIPVENVMDIKVFGEVDLNKRFLEFLSQKRIPIHFFNREGYYVGTFYPREYLNSGFLILKQAEHYINQEKRMLIAREIVSRSFQNMVDFLKKRKVRADSLTRYKKKAEEASNVSELMGIEGNAREEYYSMIDSLVSDERFRIEKRTRRPPKNFANTLISFGNSLLYTTVLSLIYQTHLDPRIGYLHETNFRRFSLNLDIAELFKPAVVDRLFLNLVNTRQINEKHFDEISEGLMLNDEGKSLFVKNYEQALRETVFHKKLNRYVSMRSLIKMELHKLEKHLIGEQVFGSEE
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Acts as a dsDNA endonuclease.  Involved in the integration of spacer DNA into the CRISPR cassette (By similarity).
What are the official names of this protein?
CRISPR-associated endonuclease Cas1.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endonuclease Cas1 family.
Protein: GATB_CORJK
Sequence: MTAPVYDYSDDVMDFDEVLEHFDPVMGMEVHVELATKTKMFSTSSAEFGDAPNSNVDPCSLGLPGALPVVNKLGVEWAIKIGLALNCEIAPKSRFARKNYFYPDQPKNYQISQYDEPIAYDGYLDVVLEDGTEWRVEIERAHMEEDTGKLTHLGGADGRIHGATASLVDCNRAGVPLIEIVTKPIEGAGERAPEVAKAYVSALRDLVKALGVSDARMDQGSMRVDSNLSLRPVGTTEYGTRTETKNINSLKSVEQAVRFEMQRQAACLVNDVEIVQETRHYQETDGTTSKGRPKETMADYRYFNDPDLPPVLAPAEWVEEIRATLPEMPWIRRARIQEEWGLKDEEMRDLVNAGALDLVVDTVEAGAKPDEARSWWVSYLAGKANEQGVELSGLDITPTQVARVASLVNEGKLTTKLARQAVDGVLAGEGDVDEVVAARGLEVVRDDGAIEAAVDEALAANPDIVEKYRAGNKKVTGAIVGAVMKATKGKADPAQVNQLIAKKLS
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: B3GA1_HUMAN
Sequence: MPKRRDILAIVLIVLPWTLLITVWHQSTLAPLLAVHKDEGSDPRRETPPGADPREYCTSDRDIVEVVRTEYVYTRPPPWSDTLPTIHVVTPTYSRPVQKAELTRMANTLLHVPNLHWLVVEDAPRRTPLTARLLRDTGLNYTHLHVETPRNYKLRGDARDPRIPRGTMQRNLALRWLRETFPRNSSQPGVVYFADDDNTYSLELFEEMRSTRRVSVWPVAFVGGLRYEAPRVNGAGKVVGWKTVFDPHRPFAIDMAGFAVNLRLILQRSQAYFKLRGVKGGYQESSLLRELVTLNDLEPKAANCTKILVWHTRTEKPVLVNEGKKGFTDPSVEI
What is the function of this protein?
Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins.  Can also play a role in glycosaminoglycan biosynthesis.  Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule.  Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin.  Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group.
What are the official names of this protein?
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1, Beta-1,3-glucuronyltransferase 1, Glucuronosyltransferase P, GlcAT-P, UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase, GlcUAT-P.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 43 family.
What are the subcellular locations of this protein?
[Isoform 1]: Golgi apparatus membrane; Single-pass type II membrane protein. Secreted. SUBCELLULAR LOCATION: [Isoform 2]: Golgi apparatus membrane; Single-pass type II membrane protein. Endoplasmic reticulum membrane. Secreted.
Protein: 1433B_MACFA
Sequence: MTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKVFYLKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGDAGEGEN
What is the function of this protein?
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways.  Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif.  Binding generally results in the modulation of the activity of the binding partner.  Negative regulator of osteogenesis.  Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2.  Negative regulator of signaling cascades that mediate activation of MAP kinases via AKAP13.
What are the official names of this protein?
14-3-3 protein beta/alpha.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
What are the subcellular locations of this protein?
Cytoplasm. Melanosome.
Protein: THIC_ALTMD
Sequence: MSNRREQRQQAQQFINELAGEAYPNSTRHYESGSRDDIRVAMRLIHQHDSLVGGTEDNPILEPNPPIPVYDTSGPYGDPKENIDVHKGLSPLRKTWIEERSDTRELDGVSSSFAKERENDIFTEDFRFIRSRKPLKAKAGKNVTQLHYARQGVITPEMEYIAIRENMGRQAIKDAELTQQHKGEHFGANLPETITPEFVRQEVAAGRAIIPCNINHPELEPMIIGRNFLVKINANIGNSAVTSSIEEEVEKLVWSTRWGADTIMDLSTGRNIHETREWLLRNSPVPLGTVPIYQALEKVNGVAEDLTWEMFKDTLIEQAEQGVDYFTIHAGVLLEYVHLTAKRVTGIVSRGGSIMAKWCLSHHQQSFLYEHFNDICEICAKYDVALSLGDGLRPGSVADANDDAQFSELRTLGELTKIAWEYDVQVMIEGPGHVPMHMIKENMEEQLKHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWYGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPHTARAYHDETLPQASGKVAHFCSMCGPKFCSMKISQEVRDVAKQAENLAPAQAAEKEKEKGMKDMANAFNKSGAELYHTADSKVELP
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: MDTJ_ECODH
Sequence: MYIYWILLGLAIATEITGTLSMKWASVSEGNGGFILMLVMISLSYIFLSFAVKKIALGVAYALWEGIGILFITLFSVLLFDESLSLMKIAGLTTLVAGIVLIKSGTRKARKPELEVNHGAV
What is the function of this protein?
Catalyzes the excretion of spermidine.
What are the official names of this protein?
Spermidine export protein MdtJ.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtJ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TBA1_APLCA
Sequence: MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPSVVDEVRSGTYRQLFHPEQLITGKEDAANNYARGHYTVGKELIDLVLDRIRKLADQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSVYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPSYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQLVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGVDSVDAEGEDEGEEY
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin alpha-1 chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: SPCAD_PARXL
Sequence: MFELTDAQRQLQQSARRLALEAIAPHAAQTDRSEQYPWHTVEALREQRLMGMTLPPEYGGKGASYFDTVLVIEELSKVCAASGRIMVESNMGAIGAIMKYGSDAQKQLAARLVLAGDKPAICITEPQAGSAASDMQTRAERRGDTWHLSGCKHWITGGGVSKLHFVFARAIEDGKDTGIAGFIVVGPDVPGMTIQRIPAMGIRGVPEARIEFDDMRVRHDMKVTPPGRTEAGFAGLMNAYNAQRVGAATVALGIAQGAFDLALDYAKRREQFGRPIAEFQGLQWMLADMSIQLEAARLMVWKAAASGSEFPSMFAAAQAKIAAGEAAIKVTNDALQIHGAVGYGRDLPLERMVRDARMFTISGGTAQILRTQVAGTLLGQKLSQRRSA
What is the function of this protein?
Catalyzes the conversion 3-sulfinopropanoyl-CoA (3SP-CoA) to propanoyl-CoA by abstraction of sulfite.  Does not show dehydrogenase activity.
What are the official names of this protein?
3-sulfinopropanoyl-CoA desulfinase, 3-sulfinopropionyl coenzyme A desulfinase, 3-sulfinopropionyl-CoA desulfinase, 3SP-CoA desulfinase.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
Protein: SK1_BLEDI
Sequence: EQFEDYGHMRF
What is the function of this protein?
Myotropic peptide.
What are the official names of this protein?
Sulfakinin-1, BleDi-SK-1.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MOBA_SHEPW
Sequence: MTITIDAVILAGGMARRMGGNDKGLVELESQPMIKHAIDRINPQVKEILINANRNQKVYSEFGFEVISDQDSGYLGPLAGMITAMSHTQADYLMVVPCDCPLLPRDLVNRMLAQLTTADAELAVASDGKREQPVVMLLKPSLRASMKAFLDAGERKIDFWYAKHNYIVTDFSDQPNAFINVNTPEQKQQLSEAIANEKNNLRCK
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATK_TRIAO
Sequence: MKEYRVYLERARSRQQDFLYPLIFREYIYGLAYSHNFNRSIFVENGGYDNKYSLLNVKRLITRMYQQNHLIISANDSNKNPFLGYNKNFYSQIISEGFAIVVEIPFFLQLSSSLEEAEIIKSYKNLRSIHSVFPFLEDKFTYLNYVSDIRIPYPIHLEILVQILRYWVKDVPFFHLLRLFLYHFCNWNCFIPTKKSISTFSKSNPRLFLFLYNFYVCEYESIFLFLRNKSYHLRLKSFSVFFERIFFYAKREHLVEVFSKDFSYTLPFFKDPNIHYVRYQGKCILASKNVPFLMNKWKYYFIHLWQCFFDVWSQPRTININQLSEHSFQLLGYFSNVRLNRSVVRSQMLQNTFLIEIVSKKLDIIVPIIPLIRSLAKAKFCNVLGHPISKPVWADSSDFDIIERFLRICRNLSHYYNGSSKKKSLYRIKYILRLSCIKTLACKHKSTVRAFLKRSGSEELLEEFFTEEEEILSLIFPRDSFTLHRFHRNRIWYLDILFSNDLVNDE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LIPS_ICTTR
Sequence: MDLRTMTQSLVTLAEDNMAFFSSQGPGETARRLSNVFAGVREQALGLEPALGSLLSVAHLFDLDPETPANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRTSHNLAELEAYLAALTQLRALAYYAQRLLATNRPGGLFFEGDEGLTADFLREYVTLHKGCFYGRCLGFQFTPSIRPFLQTISIGLVSFGEHYKRNESGLGVTASSLFTSGRFAIDPELRGAEFERITQNLDVHFWKAFWNITEIEVLSSLANMASATVRVSRLISLPPEAFEMPLTSDPKLTVTISPPLAHTGPGPVLIRLISYDLREGQDSEELNSMVKSEGPRILELRPRPQQTSRSRSLVVXFHGGGFVAQTSKSHEPYLKSWAQELGAPIISIDYSLAPEAPFPRALEECFFAYCWAVKHCALLGSTGERICLAGDSAGGNLCFTVALRAAAYGVRVPDGIMAAYPATMLQSAASPSRLLSLMDPLLPLSVLSKCVSAYAGAETEEHPNSDEKALGMMGLVRRDTSLLLRDLRLGASSWLNSFLEFSGQKSQKTSAPTVESMRRSVSEAALAQPEGPVGTDSLKILTLKDLNLKSSSETSETPEMSLSVETLGPSTPSDVNFFLRPEDAREEAEAKEGLSAKDGSSRVSNAFPEGFHPRRTSQGATQMPLYSSPIVKNPFMSPLLAPDNMLKTLPPVHIVACALDPMLDDSXMFARRLRALGQPVTLRVVEDLPHGFLSLASLCRETRQAAELCVERIRLILTPPAAAAAAAPPPL
What is the function of this protein?
Lipase with broad substrate specificity, catalyzing the hydrolysis of triacylglycerols (TAGs), diacylglycerols (DAGs), monoacylglycerols (MAGs), cholesteryl esters and retinyl esters (By similarity).  Shows a preferential hydrolysis of DAGs over TAGs and MAGs (By similarity).  Preferentially hydrolyzes fatty acid (FA) esters at the sn-3 position of the glycerol backbone in DAGs and FA esters at the sn-1 and sn-2 positions of the glycerol backbone in TAGs (By similarity).  Catalyzes the hydrolysis of 2-arachidonoylglycerol, an endocannabinoid and of 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor (By similarity).  In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production (By similarity).
What are the official names of this protein?
Hormone-sensitive lipase, HSL, Monoacylglycerol lipase LIPE, Retinyl ester hydrolase, REH.
What is the protein family that this protein belongs to?
Belongs to the 'GDXG' lipolytic enzyme family.
What are the subcellular locations of this protein?
Cell membrane. Membrane, caveola. Cytoplasm, cytosol. Lipid droplet. Note=Found in the high-density caveolae. Translocates to the cytoplasm from the caveolae upon insulin stimulation. Phosphorylation by AMPK reduces its translocation towards the lipid droplets.
Protein: TPMT_MUSSP
Sequence: MSLDMKEHPDAEVQKNRVLTLEDWKDKWVTRHISFHQEQGHQLLKKHLDTFLKGQSGLRVFFPLCGKAVEMKWFADRGHTVVGVEISEIGIREFFAEQNLSYTEEPLAEIAGAKVFKSSSGSISLYCCSIFDLPRANIGKFDRIWDRGALVAINPGDHDRYADIILSLLRKEFQYLMAVLSYDPTKHAGPPFYVPSAELKRLFGTKCSMQCLEEVDALEERHKAWGLDYLFEKLYLLTEK
What is the function of this protein?
Catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine (also called mercaptopurine, 6-MP or its brand name Purinethol) using S-adenosyl-L-methionine as the methyl donor.  TPMT activity modulates the cytotoxic effects of thiopurine prodrugs.  A natural substrate for this enzyme has yet to be identified.
What are the official names of this protein?
Thiopurine S-methyltransferase, Thiopurine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAPCB_HUMAN
Sequence: MGNAATAKKGSEVESVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF
What is the function of this protein?
Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs.  PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux.  Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis (PubMed:12420224, PubMed:21423175).  Phosphorylates GPKOW which regulates its ability to bind RNA (PubMed:21880142).
What are the official names of this protein?
cAMP-dependent protein kinase catalytic subunit beta, PKA C-beta.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Membrane; Lipid- anchor. Nucleus. Note=Translocates into the nucleus (monomeric catalytic subunit). The inactive holoenzyme is found in the cytoplasm.
Protein: AHPC_BACSU
Sequence: MSLIGKEVLPFEAKAFKNGEFIDVTNEDLKGQWSVFCFYPADFSFVCPTELEDLQEQYAALKELGVEVYSVSTDTHFVHKGWHDSSEKISKITYAMIGDPSQTISRNFDVLDEETGLADRGTFIIDPDGVIQTVEINAGGIGRDASNLVNKVKAAQYVRQNPGEVCPAKWEEGGETLTPSLDLVGKI
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Alkyl hydroperoxide reductase C, General stress protein 22, Peroxiredoxin, Thioredoxin peroxidase.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPAT_SYNP6
Sequence: MATINDNYLKLKAGYLFPEIARRVNAFAQSNPEAAIIRLGIGDVTEPLPVACRQAMIQAVEDMGQRENFKGYGPEQGYAWLREKIAAHDFQSRGCEVDASEIFISDGSKCDCGNILDIFGNNNRIAVTDPVYPVYVDTNVMAGHTGDANDRGEYDGLVYLPISAENNFTAEIPSEKVDLIYLCFPNNPTGAVASREYLQAWVDYARANGAIILFDAAYEAFITDPAIPHSIFEIPGARDCAIEFRSFSKNAGFTGTRCAFTVVPKGLKGKAADGSEVELWGLWNRRQSTKFNGVSYIVQRGAEAVYSAEGQAQIKELVAFYLENARIIREELTAAGLDVHGGVNAPYVWVKTPAGLTSWDFFDKLLQVCNVVGTPGSGFGAAGEGYFRISAFNSRENVVTAMQRIRSAGLA
What is the function of this protein?
Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis.  Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.
What are the official names of this protein?
LL-diaminopimelate aminotransferase, DAP-AT, DAP-aminotransferase, LL-DAP-aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
Protein: RS7_CENSY
Sequence: MAETQNLLLFRKWDLSDIEVVDPGLKTAISLRKMTLPYTYGRSALKRFNKADANIVERLANKMMHFGKKYAKNTGRMAGKKMGSINTVKTAFEIINLKTGRNPVEVLVRAVENSAPNEDTTRIVYGGTVYHVSVDVSPLRRVDLALRFIADGVKEAAFRKPKSLEEFLAEHLILAANNTTDAPSVKKKNELERIAQASR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: FABZ_ACISJ
Sequence: MDIHQILKLLPHRYPFLLVDRVNELERGKRILAIKNVTINEPFFTGHFPARPVMPGVLILEALAQAAGLLSFDMMGEAPGDDKVFYFVGIDGARFKRPVEPGDQLILDVELDRIKGGIYKFKGVARVGDSVACEAEIMCTMRTVA
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM3_CLOBB
Sequence: MNELIIATRKSKLAQVQTEIIMGKLKSKFNIDSKKLLIVTEGDRKLDVSLNKIGGKGLFVKDIELALLNKEAHAAVHSMKDVPFEVSSEFEITAITGREDIRDVFISNGDISFKDIKKGAKVGTSSIRRAAQLKLLRSDLEIVPIRGNVQTRLKKMEEQNLDGIVLAAAGLKRLGDENLITDYFDPKEFLPAVSQGALGIECLKDGDANKYFEALIDAEATLTVEAERSFMKELQGDCHSLIGAYSEIQGDDLYMIGIYDIGGKIVKKDILGCKTNNIELGKKLAQKILG
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: H4_RHYAM
Sequence: MTGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H4.
What is the protein family that this protein belongs to?
Belongs to the histone H4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: ZN182_MOUSE
Sequence: MAKPQEPVTFEDVAVDFTQEEWQYLNSPQRTLYRDVMLETYSNLVSVCEVASIGSEDQGGISHLSSLEQQVTKPDLIIKLEVEEPDPEDGEIPVWSFPEVCQINEQFERQHQDKQDKYLLMQVRLPNDNIITKSGQNYTDFRNAFHLSTGLLVPMQRSHKFESFGNTMVDNLNLLTGSSTENKHDTGCAKFFFHTEYENPNFIVKPCGYKEYEKTLSQKKGLSLHQRIKNGERPFECTACQKTFSKKSHLIVHWRTHTGEKPFECSECGKAFSQKSQLIIHLRTHTGERPFACPECGKAFREKSTVIIHYRTHTGEKPYECNQCGKAFTQKSNLIVHQKTHTGEKTYECTKCGESFIQKLDLIIHHSTHTGKKPHECSECKKTFSDKSTLVIHQRTHTGEKPHKCTECGKSFNEKSTLIVHQRIHTGEKPYECDVCGKTFTQKSNLGVHQRTHSGEKPFECNECEKAFSQKSYLMLHQRGHTGEKPYECNECEKAFSQKSYLIIHQRTHTEEKPYKCNECGKAFREKSKLIIHQRIHTGEKPYECLVCWKAFSQKSQLIIHQRTHTGEKPYECTECGKAFREKSTFTVHQRTHTGEKPYKCIECGKAFTQKSNLIVHQRTHTVKKAH
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 182, Zinc finger protein 21.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL11_PRB01
Sequence: MAKKVANILKLQIPAGGANPSPPVGPALGQVGVNIMDFCNAFNAETQSAEKGMPLPVVITVYEDKSFTFVVKTPPAAVLIRKILGIAKGSGEPNREKVGKLTRAQLEDIAKQKEPDLNSNDIDAAVLIIAGTARSMGVEVDL
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RS17_HAES1
Sequence: MTDKIRTVQGKVISDKMDKSFVVAIERTVKHPIYGKFIRRTTKLHVHDEHNEAKLGDVVEVRGCRPLSKTKSHTLVRVVEKAQA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.