PharMolix/UniProtQA huggingface dataset:
Protein: AATF_DROME
Sequence: MLRKSKKQPQTVAEKVSKLLAHPNESDSAEDSDFDVATGPRLVDFEEEEYDLPDARSTDFRKRNVKLLSEQSDRYKGKISSRKELDDDEDKDDEQEVSYEESDEDDENLTNFKQKLNAGGAEDSEEETAAGHSESGEESEEIESNLTDFKKKFEAGDFKYDDDEEEDDDSEEEDHSQESEGDDDDSEDDEAEDDAIKPSDVMSKTNHQAEIQKGLAVQNQLRIWERLLELRINTQKFTSKANQLPAPETLTKLASESDELQSVLNEAQERSSKLLQQLLSLQSALHQQYSEMKKSVKRKQPTEDSGPAVKKFGSVLQSNFQQMIGYRNEVLLKWDDRTKLLTPGAGVKRKSLQEDYDIIKKIGSALANREALVEKSQTPKNSQAEQQENTPVQRLKHIYDDSDFYHQQLRELIEYKASTSSNMSEITKQFVELQKLRQKMKKKVDTRASKGRKLRYVVHNKLINFMAPNESSDWTDASKSELYKSLFV
What is the function of this protein?
May function as a general inhibitor of the histone deacetylase HDAC1.
What are the official names of this protein?
Protein Aatf, Apoptosis antagonizing transcription factor ortholog.
What is the protein family that this protein belongs to?
Belongs to the AATF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DGAT2_MOUSE
Sequence: MKTLIAAYSGVLRGERRAEAARSENKNKGSALSREGSGRWGTGSSILSALQDIFSVTWLNRSKVEKQLQVISVLQWVLSFLVLGVACSVILMYTFCTDCWLIAVLYFTWLAFDWNTPKKGGRRSQWVRNWAVWRYFRDYFPIQLVKTHNLLTTRNYIFGYHPHGIMGLGAFCNFSTEATEVSKKFPGIRPYLATLAGNFRMPVLREYLMSGGICPVNRDTIDYLLSKNGSGNAIIIVVGGAAESLSSMPGKNAVTLKNRKGFVKLALRHGADLVPTYSFGENEVYKQVIFEEGSWGRWVQKKFQKYIGFAPCIFHGRGLFSSDTWGLVPYSKPITTVVGEPITVPKLEHPTQKDIDLYHAMYMEALVKLFDNHKTKFGLPETEVLEVN
What is the function of this protein?
Essential acyltransferase that catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates.  Required for synthesis and storage of intracellular triglycerides.  Probably plays a central role in cytosolic lipid accumulation.  In liver, is primarily responsible for incorporating endogenously synthesized fatty acids into triglycerides.  Functions also as an acyl-CoA retinol acyltransferase (ARAT) (By similarity).  Also able to use 1-monoalkylglycerol (1-MAkG) as an acyl acceptor for the synthesis of monoalkyl-monoacylglycerol (MAMAG) (By similarity).
What are the official names of this protein?
Diacylglycerol O-acyltransferase 2, Acyl-CoA retinol O-fatty-acyltransferase, ARAT, Retinol O-fatty-acyltransferase, Diglyceride acyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol acyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Lipid droplet. Cytoplasm, perinuclear region.
Protein: RL20_CHLPN
Sequence: MVRATGSVASRRRRKRILKQAKGFWGDRKGHIRQSRSSVMRAMAFNYMHRKDRKGDFRSLWIARLNVASRIHSLSYSRLINGLKCANISLNRKMLSEIAIHNPEGFAEIANQAKKALEATV
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit (By similarity).
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: ISPF_CLOP1
Sequence: MRIGMGYDVHKLVENRDLILGGVKIPYEKGLLGHSDADVLLHAIMDSLLGAAALGDIGKHFPDTDPKYKGADSIKLLEFVGELLNKNNYKISNIDATIIAQRPKMAPHIPTMRENIAKALNIDLDQINVKATTEEGLGFTGSGEGISSQSICLLVK
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: GCH1_BEII9
Sequence: MDDVVKSLLQRTTSSLTKPAPARPSREEAEAAVEVLLRWTGDDPSREGLRDTPKRVVKAFEEFFSGYNADASDVLSRVFEEVHGYDNMVLVRDIPFSSHCEHHMVPFFGVAHIGYYPSEAGVIGLSKLARLVDIFAKRLQTQEALTAQIIGAIDEHLQPRGCAIMLEAEHMCMSMRGVQKHGTSTLTTQFTGVFKNDPAEQVRFFGMVRNPKS
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: SYC_FRATT
Sequence: MDFCFMIFYNSLSGQKEQFKPIEANKIKMYACGVTVYDDCHIGHARTYIAFDVINRYFKYRGYDVTLVRNITDIDDKIIKRANENGESTTELVERNIKAMHDVFARLNILKPSKEPRATETIPEMVAMIETLIKKGYAYQGANSDVFYRVTKFADYGKLSKQNLEALQQGSRVDVVEEKENPMDFVLWKMAKEGEPAWDSPWGAGRPGWHIECSAMSKKLLGDTFDIHAGGSDLRFPHHENEIAQSEACNECTFANYWLHSGMVKVNAEKMSKSLNNFFTIVEVLEEYHPEVVRYFLASTVYRSEINYSKENLENAKASVERLFNALRDIEPIEVNLPDDASEYEEKFIKAMDNDFNTPEALAVLFSLAKEINTLKTTNKYKASGYAYLLRKLCDVLGILFTDIEEYFKQGDGADASEIEKLIAERTQAKKDKNYVRADEIRNQLQQQGIILEDSATGTTWKKG
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBP_TOBAC
Sequence: MAEVGLEGNQPVDLSKHPSGIVPTLQNIVSTVNLDCKLDLKAIALQARNAEYNPKRFAAVIMRIREPKTTALIFASGKMVCTGAKSEQSSKLAARKYARIIQKLGFDAKFKDFKIQNIVGSCDVKFPIRLEGLAYSHGAFSSYEPELFPGLIYRMKQPKIVLLIFVSGKIVLTGAKVRDETYTAFENIYPVLTEFRKNQQ
What is the function of this protein?
General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID.  Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II.
What are the official names of this protein?
TATA-box-binding protein, TATA sequence-binding protein, TBP, TATA-binding factor, TATA-box factor, Transcription initiation factor TFIID TBP subunit.
What is the protein family that this protein belongs to?
Belongs to the TBP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS7_CUPTR
Sequence: MRVAEVTRNTSETQIRVSLNLDGSGRQKLASGVPFLDHMLDQIARHGMFDLEVEATGDTHIDDHHTVEDVGITLGQAVARAIGDKKGITRYGHSYVPLDECLSRVVIDFSGRPGLEFHVPFTRARVGSFDVDLTIEFFRGFVNHAGVTLHIDNLRGINAHHQCETVFKAFGRALRMAVELDPRAANTIPSTKGTL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PF36P_PLAYO
Sequence: MKRRSIFMYYCFCFLLKYVAFSNVPNPNTTIGHFEICEVNTSSGDAEECVLENEFGKMFLFICDIDYNEMSKNIVLPSECAKKTYIDHVNPNGTSPEVNTYDIFPDLIAANESQFRDKFYFYGTPYSSKDIDFICLCFSETKPDIKHVMKMSFKKMTKKIKGCDFGDNIPTKKDLTNGKALYENSSCHIYAYPGDVIGINCYKKDINNIYNNNLELQPNNCFHNVYYEDDILLSSKNLIPNSRVIPDPSNDVKLSKMHSYMSYIILPDEINENVKISCACKRDEYIGTMFLYVNTSKNILTSPDNNVEEIAPLNDHYISIGDMWDMGLHENPEQIQGIISNHANKKYYEHMKIYKSNKMDSSDDDESNETESSENESNERTHNGNRANKDANNSEKMTGNRRKKNNSINNTNYYSNYEDDNGINISTHDKYYEDQHFGNNGPLRKKRTFWQNMFGTSSSYYEVFNYFSIAFILIIHMLLL
What is the function of this protein?
Involved in sporozoite infection of hepatocytes and replication therein.
What are the official names of this protein?
Sporozoite surface protein P36p, Sporozoite surface protein P52.
What are the subcellular locations of this protein?
Cell surface. Cell membrane; Lipid-anchor, GPI-anchor. Note=Present on the surface of sporozoites.
Protein: SYDND_CORDI
Sequence: MHVLRTHLAGDLGKETAGQTVTLTGWVSRRRDHGGVIFIDLRDSSGLVQVVFRENDVAEQAHHLRSEFCIKVTGEVEARPEGSENPNLASGAIEVNVTDLEILNEAAPLPFQIDDVSQGGEVGEETRLKYRYLDLRRPNQGAALRLRSQANKAARNVLDSHDFVEIETPTLTRSTPEGARDFLVPARLKPGSWYALPQSPQLFKQLLMVAGMERYYQIARCYRDEDFRADRQPEFTQLDIEMSFVDQDDVIALAEEIVSSLWKLIGYEIPTPIPRMTYADAMRLYGSDKPDLRFDIKIVECTDFFKNTTFRVFQNEYVGAVVMDGGASQPRRQLDAWQEWAKQRGAKGLAYILVGENGELTGPVSKNITDEERAGIAAHVGAKPGDCIFFAAGETKSSRALLGAARNEIAKKLDLIKEGDWAFTWVVDAPLFEPSSDATASGDVALGHSKWTAVHHAFTSPKPEWLDSFDENPGEATAYAYDIVCNGNEIGGGSIRIHRRDVQERVFKVMGITEDEAREKFGFLLDAFAFGAPPHGGIAFGWDRIVSLLGGFSSIRDVIAFPKSGGGVDPLTDAPAPIPLEQRRETGVDFKPKKKTDESAV
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBP4_YEAS7
Sequence: MEQNIISTIRDECIRHRSKYLTIAQLTAIAEAKINEFIITGKAKDQDLSSLLDKCIDILSIYKKNSKDIKNIISCKNKGAMISSNSVMIIQLNYVYYKVIHIIVTTNIPHLSEFAKIKLHKSTSDEGNGNNNNNEFQLMNIYNTLLETLLKDENIAKIKSFIKSSIKQTKLNHEQEECNLMRTGSYITSNQLNSLISSSANSTSSQMEILLIDIRSRLEFNKSHIDTKNIICLEPISFKMSYSDHDLEKKSLITSPNSEIKMFQSRNLFKFIILYTDANEYNVKQQSVLLDILVNHSFEKPISDDFTKIFILESGFPGWLKSNYGSQVSSSSPSNNNIKDDSVYINGNTSGLSLQHLPKMSPSIRHSMDDSMKEMLVAPTPLNHLQQQQQQQSDNDHVLKRSSSFKKLFSNYTSPNPKNSNSNLYSISSLSISSSPSPLPLHSPDPVKGNSLPINYPETPHLWKNSETDFMTNQREQLNHNSFAHIAPINTKAITSPSRTATPKLQRFPQTISMNLNMNSNGHSSATSTIQPSCLSLSNNDSLDHTDVTPTSSHNYDLDFAVGLENLGNSCYMNCIIQCILGTHELTQIFLDDSYAKHININSKLGSKGILAKYFARLVHMMYKEQVDGSKKISISPIKFKLACGSVNSLFKTASQQDCQEFCQFLLDGLHEDLNQCGSNPPLKELSQEAEARREKLSLRIASSIEWERFLTTDFSVIVDLFQGQYASRLKCKVCSHTSTTYQPFTVLSIPIPKKNSRNNITIEDCFREFTKCENLEVDEQWLCPHCKKRQPSTKQLTITRLPRNLIVHLKRFDNLLNKNNDFVIYPFLLDLTPFWANDFDGVFPPGVNDDELPIRGQIPPFKYELYGVACHFGTLYGGHYTAYVKKGLKKGWLYFDDTKYKPVKNKADAINSNAYVLFYHRVYGV
What is the function of this protein?
Ubiquitin thioesterase that acts at the late endosome/prevacuolar compartment to recover ubiquitin from ubiquitinated membrane proteins en route to the vacuole.  Removes also ubiquitin from soluble proteins targeted to proteasomes.  Is essential to maintain a normal level of free ubiquitin.  Involved in the ammonium-induced down-regulation of the GAP1 permease and the UME3 destruction in response to oxidative stress.  Has a role in the RAD9 checkpoint response to TOP1 poisons.  Required for promoting coordination of DNA replication and avoids DNA overreplication (By similarity).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 4, Deubiquitinating enzyme 4, Ubiquitin thioesterase 4, Ubiquitin-specific-processing protease 4, Vacuole biogenesis protein SSV7.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
What are the subcellular locations of this protein?
Cytoplasm. Late endosome membrane; Peripheral membrane protein. Note=Recruited to the late endosome by BRO1.
Protein: MCH1_ONCKI
Sequence: MRDSVLSVIFALALFLECYTPSMAIPMGKMEDTALEQDTLDSLLNESVADKNPDSVRSGSSKIIVLADSGMWKNLNRGLPLYKLKAAAAGLDRALTLDRREADQDLSPSISIVRRDTMRCMVGRVYRPCWEV
What is the function of this protein?
Plays a role in skin pigmentation by antagonizing the action of melanotropin alpha.  Induces melanin concentration within the melanophores.  May participate in the control of the hypothalamo-pituitary adrenal gland axis by inhibiting the release of ACTH.
What are the official names of this protein?
Pro-MCH 1.
What is the protein family that this protein belongs to?
Belongs to the MCH family.
Protein: CBIX_SYNY3
Sequence: MTLTSVPAPVSLFPELELPPLPYHRPLLMIGHGTRDEDGRQTFLDFVAQYQALDHSRPVIPCFLELTEPNIQAGVQQCVDQGFEEISALPILLFAARHNKFDVTNELDRSRQAHPQINFFYGRHFGITPAILDLWKARLNQLDSPEANPQGIDRQDTVLLFVGRGSSDPDANGDVYKMARMLWEGSGYQTVETCFIGISHPRLEEGFRRARLYQPKRIIVLPYFLFMGALVKKIFTITEEQRATFPEIEIQSLSEMGIQPELLALVREREIETQLGQVAMNCEACKFRLAFKNQGHGHDHGHGHHHHGHDHGHSHGEWVDTYIEPTAYHEKIWQAP
What is the function of this protein?
Chelates cobalt to the cobalamin precursor as part of the anaerobic pathway to cobalamin biosynthesis.
What are the official names of this protein?
Sirohydrochlorin cobaltochelatase, CbiXL.
What is the protein family that this protein belongs to?
Belongs to the CbiX family. CbiXL subfamily.
Protein: PDXJ_HELPS
Sequence: MRFGLNIDHIVTLREIRKTYEPEILEALFIAKNTHKVDLITIHLREDKRHIQNEDVLRLLEISPLPINIECSINAGITDFLCSLKNKPSKVTIVPENRNEVTTEGGLDCSLKGLGEVIRAYHNKGVEVSLFIDPLKDALHFAREHQVKQVEFHTGVYANLHNALYSNANNQIHAISALKDKSPKELKEELHNAFLQLRKMSKEAFFMGITACAGHGLNYSNVKELLKIPSLRELNIGHSVISKAVLVGLEKAILEMAQLIKR
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOK_HELPY
Sequence: MIGLNHYLIVSGLLFCIGLAGMLKRKNILLLFFSTEIMLNAINIGFVAISKYTHNLDGQMFALFIISIAASEVAIGLGLVILWFKKFKSLDIDSLNAMKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: C_VSIVM
Sequence: MRSKHNELKSPIMSCSKRTEWKSILGPLIFRQQMILTQNLNQKLKTIKACMYQIRKLSKLKALYRGL
What is the function of this protein?
May play a role in viral pathogenesis or transmission by insects vectors.
What are the official names of this protein?
Protein C'.
What is the protein family that this protein belongs to?
Belongs to the rhabdoviruses C protein family.
Protein: DCUP_STAES
Sequence: MIQLWGDSRLRSKNDTILKAIKGESTSHTPVWFMRQAGRSQPEYRKLKEKYSLFEITHQPELCAYVTHLPVDNYQTDAAVLYKDIMTPLKPIGVDVEIKSGIGPVISNPIQTVKDVERLSQIDPKRDVPYVLDTIKLLTEEKLNVPLIGFTGAPFTLASYMIEGGPSKNYNFTKAMMYRDEETWFALMNHLVDISIDYVVAQVEAGAEIIQIFDSWVGALNVKDYRYYIKPAMNKLISGIKAYYDVPIILFGVGASHLINEWNDLPIDVLGLDWRTTIKQADKMGVNKAIQGNLDPSILLAPWDVIESRLKDILNQGLNRGKYIFNLGHGVFPEVKPETLRKVTEFVHNYTAK
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPN1_YARLI
Sequence: MLPKTLTIWASLASLAVAQSGQVVFAKNADGKFVHSTDDLDQGQRKIRGKFLHITDIHPDPYFHVGAVAEDKCHVDPDHKDSDYPDEDSELVWFRATGKKKHNHHKGKDHEKMPKAGYYGHPLSSCDGPISLMNATFDWIDQNIRDEIDFIIWTGDNVRHDNDNRYPRLEQDIFGYNQIVSSKFHELFRYNETRDGEGHNGGGDPQHPLVIPIIPSLGNNDVFPHNLYLAGPSFQSRRMLQIWSEFVPEAQQHIFSRGSYYFQEVITGKLAVISLNTLYFYKSNPMSDGCDEKTDPGYKHLVWLGVVLDEMRQRGMKVWLSGHVPPVEKNYEDSCHLKLAYWLTEYRDIIVGSVFGHMNIDHFVVMDPKKIEKAQSQDLGTPGLGYKSHVTDFLDVAISASHPVHTFGSIYKRNYIESVREDYSEIPGPKKWLDEYASNFAIAHVSPSVIPNYFPSLRVWEYNITGLGEEIGNPPHPPPSFRAWSDVLEEFERDYAQDVMDEIEVEWFDANSDVIEAEDNDGDDDEDENEDDPEMLTEEAIKEGVANINPETGTLASIFGGLKFWKSSTAVATSSEPESDDYDSDLDAERKKGKKKGKKGKKGKKGKKGKKKKGKKGKKGKKGKRDKSMPPKFPKDLQPGPAYIPQLFTPIGYTQYYANITQFNKEYKKTGASNFEYVVEYTTNDAPYNFEHLTVRNWVELARVLGKNFRDLDLEAEKSKSDQLWKVYMDRAFVGTGAEYLEEPDDD
What is the function of this protein?
Catalyzes the hydrolysis of inorganic polyphosphate (polyP) chains of many hundreds of phosphate residues into shorter lengths.
What are the official names of this protein?
Endopolyphosphatase.
What is the protein family that this protein belongs to?
Belongs to the endopolyphosphatase PPN1 family.
What are the subcellular locations of this protein?
Vacuole membrane; Single-pass type II membrane protein.
Protein: PUR5_ECOSM
Sequence: MTDKTSLSYKDAGVDIDAGNALVGRIKGVVKKTRRPEVMGGLGGFGALCALPQKYREPVLVSGTDGVGTKLRLAMDLKRHDTIGIDLVAMCVNDLVVQGAEPLFFLDYYATGKLDVDTASAVISGIAEGCLQSGCSLVGGETAEMPGMYHGEDYDVAGFCVGVVEKSEIIDGSKVSDGDVLIALGSSGPHSNGYSLVRKILEVSGCDPQTTELDGKPLADHLLAPTRIYVKSVLELIEKVDVHAIAHLTGGGFWENIPRVLPDNTQAVIDESSWQWPEVFNWLQTAGNVERHEMYRTFNCGVGMIIALPAPEVDKALALLNANGENAWKIGIIKASDSEQRVVIE
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WECC_METVS
Sequence: MDKHEKQKIKKICVIGLGYIGLPTASMLANHGYEVIGVDISEKRVNEIKNGDFKIEEPGLLTLLKGAINSKNLNVKTKAEKADAFIICVPTPAIGCDDGSKKCDLSYVLDAVNSILPYIDEGNLIVIESTIPPETTQKIYDIIDKKVYVAHCPERVLPGKILKELVENDRIIGGINKKSAEMAKEIYKSFVEGKIYITDSNTAEMVKLMENTYRDINIALANEFAKICDEIGVNVWDAIKIANKHPRVNILNPGPGVGGHCISIDPWFIVEKTNNAKFIRSARELNDKMPYYVCNMIISELKNLNIEKPKVTVFGATYKGNVEDTRESPSKKVIDALAEKNIPVSTYDPHANSFEYELHSLEDSIVNSDCIVVLTDHNEFKSFKKEEIDEISKKLKNKLIIDTKNILNHNLWKKAGFKIKLLGNGAW
What is the function of this protein?
Catalyzes the four-electron oxidation of UDP-N-acetyl-D-mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N-acetylmannosaminuronic acid (UDP-ManNAcA).
What are the official names of this protein?
UDP-N-acetyl-D-mannosamine dehydrogenase, UDP-ManNAc 6-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
Protein: DUT_FOWPN
Sequence: MEEVTVYKISDRAKLPYKQTSYSAGYDLYSAYDYVIEPMNKELIKTDIILKIPNGYYGRIAPRSGLAYNYFIDVGAGVIDSDYRGNVGVLLFNFGSTQFNVCKGDRIAQIIFEKIAYPKIIEVTTLEEINITDRGNSGFGSTGLK
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: PAQR7_HUMAN
Sequence: MAMAQKLSHLLPSLRQVIQEPQLSLQPEPVFTVDRAEVPPLFWKPYIYAGYRPLHQTWRFYFRTLFQQHNEAVNVWTHLLAALVLLLRLALFVETVDFWGDPHALPLFIIVLASFTYLSFSALAHLLQAKSEFWHYSFFFLDYVGVAVYQFGSALAHFYYAIEPAWHAQVQAVFLPMAAFLAWLSCIGSCYNKYIQKPGLLGRTCQEVPSVLAYALDISPVVHRIFVSSDPTTDDPALLYHKCQVVFFLLAAAFFSTFMPERWFPGSCHVFGQGHQLFHIFLVLCTLAQLEAVALDYEARRPIYEPLHTHWPHNFSGLFLLTVGSSILTAFLLSQLVQRKLDQKTK
What is the function of this protein?
Plasma membrane progesterone (P4) receptor coupled to G proteins (PubMed:23763432).  Seems to act through a G(i) mediated pathway (PubMed:23763432).  May be involved in oocyte maturation (PubMed:12601167).  Involved in neurosteroid inhibition of apoptosis (PubMed:23161870).  Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone (PubMed:23161870).
What are the official names of this protein?
Membrane progestin receptor alpha, mPR alpha, Membrane progesterone P4 receptor alpha, Membrane progesterone receptor alpha, Progesterone and adipoQ receptor family member 7, Progestin and adipoQ receptor family member 7, Progestin and adipoQ receptor family member VII.
What is the protein family that this protein belongs to?
Belongs to the ADIPOR family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPOZ_HALHL
Sequence: MARVTVEDCLDNVDNRFELVLAGAKRARQLAKGIEPLVDWENDKPTVVALREIAAGHVTSEILTSTEESAADSLSLGGFSTADVEAEVGGGPVQPDPGASQERAFDEAADGTAQGSGDPDPTT
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: MURG_STRTD
Sequence: MAKSKKIVFTGGGTVGHVTLNLILIPKFLKDGWEVHYIGDKHGIEHEQIDKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGILQSIAIIAKIRPQALFSKGGFVSVPPVIASKLLRVPVYVHESDLSMGLANKIAYKFATTMFTTFEQSKTLVKTRHVGAITKVGMTRFDNSDQLDKIKEQFDEKLKTVLFIGGSTGAKVFNDFISKTPELIENYNIINISGDSSLNTLERHLYRVDYVTDLYQPLMDMADLVVTRGGSNTIFELLAMKKLHLIVPLGKEASRGDQLENADYFERKGYARQLQEPELSWETLKHELEQLVEHAETYKEAMAKSEEITSPDDFYNLLVTSISNK
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: REP_BACSP
Sequence: MAEHYEALESKIGAPYYAKKAEKLISCAEYLSFKRDPETGKLKLYQAHFCKVRLCPMCAWRRSLKIAYHNKLIVEEANRQYGCGWIFLTLTVRNVKGERLKPQISEMMEGFRKLFQYKKVKTSVLGFFRALEITKNHEEDTYHPHFHVLIPVRKNYFGKNYIKQAEWTSLWKKAMKLDYTPIVDIRRVKGKAKIDAELIENDVREAMMEQKAVLEISKYPVKDTDVVRGNKVTEDNLNTVLYLDDALAARRLIGYRGILKEIHKELNLGDAEDGDLVKIRKKMTRLQMVHLRLWLIGILHIKNYIIK
What are the official names of this protein?
Protein rep, Replication protein.
What is the protein family that this protein belongs to?
Belongs to the Gram-positive plasmids replication protein type 1 family.
Protein: ATPA_CHLTE
Sequence: MSTAVRPDEVSSILRKQLAGFESEADVYDVGTVLQVGDGIARIYGLSKVAAGELLEFPHNVMGMALNLEEDNVGAVLFGESNAVKEGDTVKRTNILASIPVGEAMLGRVINPLGEPIDGKGPINTDIRLPLERRAPGVIFRKSVHEPLQTGLKAIDAMIPIGRGQRELIIGDRQTGKTAVALDTIINQKGKGVQCIYVAIGLKGSTVAQVVNTLEKYGAMEYTTVVSATASDPAPLQFIAPFAGATIGEFFRDTGRHALVVYDDLSKQAVAYRQLSLLLRRPPGREAYPGDVFYLHSRLLERAAKITDDIEVAKKMNDLPEPLKPLVKGGGSLTALPVIETQAGDVSAYIPTNVISITDGQIFLESNLFNAGQRPAINVGISVSRVGGAAQIKAMKKVAGTLRLDLAQFRELEAFSKFGSDLDKSTKAQLDRGARLVEILKQGQYIPMPVEKQVAIIFIGTQGLLDSVDLKQVRRFEEEFLAMLEQKHPEILSSIAEKGTLESDIASKLKELGEKYVASFKEKSKA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RSBW_BACCR
Sequence: MMERFEKIEMKIPAKAEYVAIIRLTMAGVANRMGFAYDDIEDMKIAISEACTNIVQHAYKEDVGEIAIVFGLYENRLEIMVADNGVSFDFNNLKRKVGPYDISKPVEHLPENGLGLYLINTLMDDIQIMHDEGMTVLMTKYIQREQVENDGNPISTYESY
What is the function of this protein?
Negative regulator of sigma-B activity.  Phosphorylates and inactivates its specific antagonist protein, RsbV.  Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).
What are the official names of this protein?
Serine-protein kinase RsbW, Anti-sigma-B factor, Sigma-B negative effector RsbW.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-factor family.
Protein: YQGF_HYPNA
Sequence: MAVVDLFDLPREGVLLGIDPGTATIGVAATDRIRMMASPVETILKKKLAPSLERLLHIYDERAAVGLIVGLPLNVDGSMGPRAQSVRTLVSSLLKVRDLPVTFQDERYSSAEAGDIMRAAGATRRNREARIDASAAAVILQDALSRLERRP
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.