PharMolix/UniProtQA huggingface dataset:
Protein: THI4_AJECG
Sequence: MSPPSATYDVVAAAATSVAKTNKPSTAHGSLTSTSTILDEFAGKWDDFSFGHIRESQVSRAMTRRYFEDLDTYAESDIVIVGAGSCGLSTAYVLGKARPDLKIAVIEASVSPGGGAWLGGQLFSAMVLRKPADRFLDDLGVPYEEEPSNPNMVVIKHAALFTSTLLSKVLSFPNIKLFNATCVEDLITRPAPAAGDGEGIRIAGVVTNWTLVTLHHDDHSCMDPNTINAPLVISTTGHDGPFGAFCAKRLVSMAAIEKLGGMRGLDMNSAEEAIVKNTREVTKGLIIGGMELSEIDGWHRMGPIFSAMMLSGVRAAEVALEVFEERKRECADKK
What is the function of this protein?
Involved in biosynthesis of the thiamine precursor thiazole.  Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate.  The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate.  The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme.  May have additional roles in adaptation to various stress conditions and in DNA damage tolerance.
What are the official names of this protein?
Thiamine thiazole synthase, Thiazole biosynthetic enzyme.
What is the protein family that this protein belongs to?
Belongs to the THI4 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RHMD_BURO0
Sequence: MSMPTIRAVRALTVRGGGADYHDQDAGHWIDDHIATPMSRYPEYRQSRQSFGINVLGTLVIEVEASDGTVGFAVTTGGEIGAFIVERHLARFIEGQRVTDIEKMWDQMFHATLYYGRKGVVLNAISGVDLALWDLLAKVRREPVHQLLGGKVRDELEFYATGARPDLAKEMGFIGGKLPLHHGPAEGEAGLRRNLDALADMRSRVGADFWLMLDCWMSLDVPYATRLAHEAHALGLKWIEECLPPDDYWGYAKLRRDVPRGMLVTTGEHEATRWGFRMLLEMECCDIIQPDVGWCGGLTELIRISALADARGVLVIPHGSSVYSYHFVATRHNSPFAEFLMMAPQADRVVPMFDPLLLDEPVPVGGRMKVPDTPGFGVRLNPDVRMQRPYEH
What is the function of this protein?
Catalyzes the dehydration of L-rhamnonate to 2-keto-3-deoxy-L-rhamnonate (KDR).
What are the official names of this protein?
L-rhamnonate dehydratase, RhamD.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. RhamD subfamily.
Protein: ABRX1_XENLA
Sequence: MEGESTTAVISGFVFGALTFHHLNSGSDTEGFLLGDVMGEAKNSITDSQMDDVEVLYTIDIQKHVPCYQLSRFYNALGDLNIPELKKLLAGQKKSQNVIGWYKFRHNTEQIMTFRERLLHKNLQEHFSNSGLVFLLLTSNPATETKSTHRLEYALHKPQDGFFHKVPLVISNLGMSDQQGYKTLCGSCVSVGLNTAIKKHRLEFFNEDGALAEVNRISDMHMTLQEELKKTCSQLVESENSVEQLLEAVNDLKKQIAEKKLLMEEKGNKVSEDTEENVLLCEAFRRFFPQSALLQSCRLSLGGRQIPHSCSVSHNSSDVNELTLMVKQYDFPEAHRRQAGKRKAHSKQLGKTSTKKSRLPPFQRPQSDNSDSESSDSEKLLCTSGTETDGDIVQSLNVEVSRSKSPTF
What is the function of this protein?
Involved in DNA damage response and double-strand break (DSB) repair.  Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of brca1.  The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the brca1-bard1 heterodimer to sites of DNA damage at DSBs.  This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX (By similarity).
What are the official names of this protein?
BRCA1-A complex subunit Abraxas 1, Coiled-coil domain-containing protein 98, Protein FAM175A.
What is the protein family that this protein belongs to?
Belongs to the FAM175 family. Abraxas subfamily.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes at sites of DNA damage at double-strand breaks (DSBs).
Protein: SFH5_ARATH
Sequence: MSGSLDRFARPCFEGVSSNDERRERRSDFEVSEDEKKTRIGNFNFKKKAAKASSKLRHSLKKKGSSRRRSSDRTFSLTIEDIHDVEELRAVDEFRNLLVSENLLPPTLDDYHIMLRFLKARKFDIGKTKLMWSNMIKWRKDFGTDTIFEDFEFEEFDEVLKYYPHGYHGVDKEGRPVYIERLGLVDPAKLMQVTTVERFIRYHVREFEKTVNIKLPACCIAAKRHIDSSTTILDVQGVGFKNFSKPARDLIIQLQKIDNDNYPETLHRMFIINGGSGFKLVWATVKQFLDPKTVTKIHVIGNKYQNKLLEIIDASQLPDFLGGTCTCADRGGCMRSDKGPWNDPEILKMLQSGGPLCRHNSALNSFSRVSSCDKPSFSGIKASDTSTAESGSEVEEMASPKVNRELRVPKLTPVCEDIRGTAISYPTDSSEYDSPMVDKVVDVAWMAHEKPKASKGSEDTPDSGKIRTVTYIWRWLMMFFVNLFTLLISLALPQREGHSQSESSVDGPNARESRPPSPAFATIAERNVFSSVVNRLGDLEKQVETLHSKRHEMPREKEELLNTAVYRVDALEAELIATKKALHEALMRQDDLLAYIDREEDEKYHKKKKVCW
What is the function of this protein?
Required for transport of secretory proteins from the Golgi complex.  Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro (By similarity).
What are the official names of this protein?
Phosphatidylinositol/phosphatidylcholine transfer protein SFH5, Protein SEC FOURTEEN HOMOLOGS 5, AtSFH5.
What is the protein family that this protein belongs to?
Belongs to the SFH family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein.
Protein: RL4_TRIV2
Sequence: MVESVVKNWQGEQVGQKTFELRVAKETTAAHIVHRALVRQQTNARQGTASTKTRAEVRGGGRKPWRQKGTGRARAGSIRSPLWRGGGVIFGPKPRDFDLKMNRKERRLALRTALVSRIDDLILVEEFSNELSRPKTKDLVAAFTRWGAEPESKILLILSEFPENVYLSARNIENLKLIAADQLNVYDLLHADKIVVTTSALEKIQEVYNG
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: DHLE_THEIN
Sequence: MKIFDYMEKYDYEQLVMCQDKESGLKAIICIHVTTLGPALGGMRMWTYASEEEAIEDALRLGRGMTYKNAAAGLNLGGGKTVIIGDPRKDKNEAMFRALGRFIQGLNGRYITAEDVGTTVEDMDIIHEETRYVTGVSPAFGSSGNPSPVTAYGVYRGMKAAAKEAFGDDSLEGKVVAVQGVGHVAYELCKHLHNEGAKLIVTDINKENADRAVQEFGAEFVHPDKIYDVECDIFAPCALGAIINDETIERLKCKVVAGSANNQLKEERHGKMLEEKGIVYAPDYVINAGGVINVADELLGYNRERAMKKVEGIYDKILKVFEIAKRDGIPSYLAADRMAEERIEMMRKTRSTFLQDQRNLINFNNK
What is the function of this protein?
Catalyzes the reversible deamination of L-leucine to 4-methyl-2-oxopentanoate.  Exhibits the highest activity with L-leucine as substrate, but can also use other L-amino acids such as L-isoleucine, L-valine and L-2-aminovaleric acid.  All of the oxo analogs of the amino acid substrates serve as good substrates for the reverse reaction.
What are the official names of this protein?
Leucine dehydrogenase, LeuDH.
What is the protein family that this protein belongs to?
Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
Protein: GLGB_BURCM
Sequence: MTDMLFDRTDIDALLAGRHPDPFACLGPHTDAGRVVVRALLPGAQRVRAVTPDGDELGALACVDDAGCFAGTLAHDGRYRLAIDWPDTRQITDDAYAFGTLLDEAALARFAAGDPAAVLDCLGATPTRVDGVDGVRFAVWAPNAQRVSVVGDFNMWDGRRHPMRLRRPWGVWELFVPGIGAGEHYKYELRAADGHVLPHKADPCARATEAPPRTASVVADTAALDAFAWHDDGWLHARPPADQRFRMPWSIYEVHAESWQRVPEDMDRSANWDELAERLIPYVRGMGFTHVEFMPISEYPFGGSWGYQPLAQFAPSARFGPVDGFARFVDRAHAAGIGVIVDWVPAHFPNDAHGLAQFDGSALYEHADPREGMHPDWNTCVFNLGRNEVSAFLIASALAWARRYHVDGIRVDAVASMLYRDYSRNEGEWVPNIHGGRENLESVAFLRALNDTLHGTLAPPGVVTFAEESTAWPGVTASTGDGGLGFDFKWNMGWMHDTLSYVREDPIHRRYHHDRMTFGLVYAFSERFVLPLSHDEVVHGKGSLAVKMPGDAWQRLATLRAYFGFMWAHPGKKLLFMGSEFAQWAEFAHDATPHWDLLDAPAHRGVQRLVRDLNRTYAAEPALHALDCHASGFFWLIGDDRDNSVFAFARRDDSGRLVVAICNFTPVPRPGYRIGLPAPGHWRELMNTDAAVYGGTNAGNDGAVWTEDVPSHGQSWSATLRLPPLATLWLSPA
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: MNMA_HELAH
Sequence: MKIAVLLSGGVDSSYSAYNLKEQGHELVGIYLKLHASEKKHDLYIKNAQKACEFLGIPLEVLDFQKDFKSVVYDAFISAYEEGQTPNPCALCNPLMKFGLALDHALKLGCEKIATGHYARIEENDKVSYIREALDKTKDQSYFLYALEHEVIAKLVFPLGDLLKKDIKPLALNAMPFLGTLETYKESQEICFVEKSYIDTLKKHVEVEKEGVVKNLQGKIIGTHKGYMQYTIGKRKGFNIKGALEPHFVVRIDAKKNELVVGKKEDLATHFLKAKNKSLMKDFKSGEYFIKARYRSMPTKAFVSLKDEMIEVELKEPFYGVAKGQALVVYKDDIVLGGGVIV
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADGB_HUMAN
Sequence: MASKQTKKKEVHRINSAHGSDKSKDFYPFGSNVQSGSTEQKKGKFPLWPEWSEADINSEKWDAGKGAKEKDKTGKSPVFHFFEDPEGKIELPPSLKIYSWKRPQDILFSQTPVVVKNEITFDLFSANEHLLCSELMRWIISEIYAVWKIFNGGILSNYFKGTSGEPPLLPWKPWEHIYSLCKAVKGHMPLFNSYGKYVVKLYWMGCWRKITIDDFLPFDEDNNLLLPATTYEFELWPMLLSKAIIKLANIDIHVADRRELGEFTVIHALTGWLPEVISLHPGYMDKVWELLKEILPEFKLSDEASSESKIAVLDSKLKEPGKEGKEGKEIKDGKEVKDVKEFKPESSLTTLKAPEKSDKVPKEKADARDIGKKRSKDGEKEKFKFSLHGSRPSSEVQYSVQSLSDCSSAIQTSHMVVYATFTPLYLFENKIFSLEKMADSAEKLREYGLSHICSHPVLVTRSRSCPLVAPPKPPPLPPWKLIRQKKETVITDEAQELIVKKPERFLEISSPFLNYRMTPFTIPTEMHFVRSLIKKGIPPGSDLPSVSETDETATHSQTDLSQITKATSQGNTASQVILGKGTDEQTDFGLGDAHQSDGLNLEREIVSQTTATQEKSQEELPTTNNSVSKEIWLDFEDFCVCFQNIYIFHKPSSYCLNFQKSEFKFSEERVSYYLFVDSLKPIELLVCFSALVRWGEYGALTKDSPPIEPGLLTAETFSWKSLKPGSLVLKIHTYATKATVVRLPVGRHMLLFNAYSPVGHSIHICSMVSFVIGDEHVVLPNFEPESCRFTEQSLLIMKAIGNVIANFKDKGKLSAALKDLQTAHYPVPFHDKELTAQHFRVFHLSLWRLMKKVQITKPPPNFKFAFRAMVLDLELLNSSLEEVSLVEWLDVKYCMPTSDKEYSAEEVAAAIKIQAMWRGTYVRLLMKARIPDTKENISVADTLQKVWAVLEMNLEQYAVSLLRLMFKSKCKSLESYPCYQDEETKIAFADYTVTYQEQPPNSWFIVFRETFLVHQDMILVPKVYTTLPICILHIVNNDTMEQVPKVFQKVVPYLYTKNKKGYTFVAEAFTGDTYVAASRWKLRLIGSSAPLPCLSRDSPCNSFAIKEIRDYYIPNDKKILFRYSVKVLTPQPATIQVRTSKPDAFIKLQVLENEETMVSSTGKGQAIIPAFHFLKSEKGLSSQSSKHILSFHSASKKEQEVYVKKKAAQGIQKSPKGRAVSAIQDIGLPLVEEETTSTPTREDSSSTPLQNYKYIIQCSVLYNSWPLTESQLTFVQALKDLKKSNTKAYGERHEELINLGSPDSHTISEGQKSSVTSKTTRKGKEKSSEKEKTAKEKQAPRFEPQISTVHPQQEDPNKPYWILRLVTEHNESELFEVKKDTERADEIRAMKQAWETTEPGRAIKASQARLHYLSGFIKKTSDAESPPISESQTKPKEEVETAARGVKEPNSKNSAGSESKEMTQTGSGSAVWKKWQLTKGLRDVAKSTSSESGGVSSPGKEEREQSTRKENIQTGPRTRSPTILETSPRLIRKALEFMDLSQYVRKTDTDPLLQTDELNQQQAMQKAEEIHQFRQHRTRVLSIRNIDQEERLKLKDEVLDMYKEMQDSLDEARQKIFDIREEYRNKLLEAEHLKLETLAAQEAAMKLETEKMTPAPDTQKKKKGKKK
What is the function of this protein?
Required for sperm flagellum formation and maturation of elongating spermatids, thus playing an essential role in male fertility.  Contributes to in vitro proteolytic cleavage of SEPT10 in a calmodulin-dependent manner.
What are the official names of this protein?
Androglobin, Calpain-7-like protein.
What is the protein family that this protein belongs to?
Belongs to the peptidase C2 family.
Protein: ARNF_PHOLL
Sequence: MKGYIWGLISVLLVTIAQLLLKWGVVNLPALNLGLHWFDIEWLWSHRHSLVAVMAGLAGYLLSMLCWLFTLKYLPLNKAYPLISLSYVFVYLMVALLPWFNETITLLKTAGVIFILYGVWLISRPE
What is the function of this protein?
Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
What are the official names of this protein?
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF, L-Ara4N-phosphoundecaprenol flippase subunit ArnF, Undecaprenyl phosphate-aminoarabinose flippase subunit ArnF.
What is the protein family that this protein belongs to?
Belongs to the ArnF family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LEUD_ACIB3
Sequence: MKAYTVEQGIVAPLDRANVDTDLIIPKQFLKSIKRTGFGDNLFDELRYLDEGYPGQDNSVRPKNPDFVLNQPRYQGATVLIARTNFGCGSSREHAPWALNEYGFRTVIAPSFADIFFNNCFKNGMLPVILPEDIVDQLFKECAAQEGYQLTIDLAAQEVRTPTGEAFKFEVDPFRKHCLLNGLDDIGLTLQNADAIRAYEEKTKQVRPWVFQEIN
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: GLPK_ECO24
Sequence: MTEKKYIVALDQGTTSSRAVVMDHDANIISVSQREFEQIYPKPGWVEHDPMEIWATQSSTLVEVLAKADISSDQIAAIGITNQRETTIVWEKETGKPIYNAIVWQCRRTAEICEHLKRDGLEDYIRSNTGLVIDPYFSGTKVKWILDHVEGSRERARRGELLFGTVDTWLIWKMTQGRVHVTDYTNASRTMLFNIHTLDWDDKMLEVLDIPREMLPEVRRSSEVYGQTNIGGKGGTRIPISGIAGDQQAALFGQLCVKEGMAKNTYGTGCFMLMNTGEKAVKSENGLLTTIACGPTGEVNYALEGAVFMAGASIQWLRDEMKLINDAYDSEYFATKVQNTNGVYVVPAFTGLGAPYWDPYARGAIFGLTRGVNANHIIRATLESIAYQTRDVLEAMQADSGIRLHALRVDGGAVANNFLMQFQSDILGTRVERPEVREVTALGAAYLAGLAVGFWQNLDELQEKAVIEREFRPGIETTERNYRYAGWKKAVKRAMAWEEHDE
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: GUAAB_METAR
Sequence: MVDANAFIDEAIADIKLKVGNGKALIALSGGVDSSVCAILAHRALGDRLIPVYVDTGLMRKGETDRIREIFKFMNPHVVDASDRFFNALKGVTDPEAKRKIVGEMFIRVFEDVVKGLEVDFLIQGTIYPDRIESEGGIKSHHNVGGLPSVTEFKGIIEPLQDLYKDEVREVARALPLPEEISERMPFPGPGLSVRVIGEVTREKIAVVREANAIVEQELVHQFKPWQCLAALLEKGTGVKGDNRCHGWIIAVRAVESRDAMTANHMELPWETLNKISSRITSEIPSVARVVYDITPKPPATIEFE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing] subunit B, GMP synthetase.
Protein: LY6G_MOUSE
Sequence: MDTCHIAKSCVLILLVVLLCAERAQGLECYNCIGVPPETSCNTTTCPFSDGFCVALEIEVIVDSHRSKVKSNLCLPICPTTLDNTEITGNAVNVKTYCCKEDLCNAAVPTGGSSWTMAGVLLFSLVSVLLQTFL
What are the official names of this protein?
Lymphocyte antigen 6G, Ly-6G, Ly-6G.1.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: CTPM_PSEAE
Sequence: MMRLTLKSKVLLLAMVPVLLFALVLSGGAVLILKKQADAEVKDTRERLLGDRRAELEHYVQIAMGSIQAEYDRSANGDLNARAEAIARLSKIKYGKDGYIFGYDSQVVRLFRGDSPVDVGKSFRDRRDPSGVYLNRELVEAGRNGSHYVTYTSPLPGNESVMVPKLSYTLYLPKWDMVIGSAINLDGVEAQLVEIKQDIDERIGTLIASIVGIAGVLLVVLLVIGLAVANAMLRPLHQIRQNLDDIAAGEGDLTRRLPVTSYDELGELAGSFNRFVEKIHGLVRQIAGMTGDLKQLVEQMSAQAERSEQAMERQRHETDQVATAINEMSAAAHEVAQSAQRAAEAAQQTDHEGQAAKRVVDGSIERIHALVDEIRDSGTSLDSLQQDVQSIVSVLGVIRSIAEQTNLLALNAAIEAARAGEAGRGFAVVADEVRALASRTQQSTQEIQGMIDRLQQGTNAAVDAMRRSGEAGEGTSNQANQAGDSLDAIAQLIATINAMNAQIASAAEEQTAVAEEINRSVHQIAGAVDSVADEAQQGAQTARSLAQLGQGLGRLVGQFRI
What is the function of this protein?
Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation (Probable).  Directly recognizes five C4-dicarboxylic acids: L-malic, citramalic, citraconic, bromosuccinic and methylsuccinic acids (PubMed:17933940, PubMed:29391435).  Three of the identified ligands act as chemoattractants (L-malic, D,L-bromosuccinic and L-citramalic acids) whereas two of them (L-methylsuccinic and citraconic acids) behave as antagonists by inhibiting the downstream chemotaxis signaling cascade (PubMed:29391435).  Antagonists compete with chemoattractants, thereby decreasing the affinity for chemoattractants and the subsequent chemotactic response (PubMed:29391435).  Acts through the che chemosensory pathway (PubMed:29391435).
What are the official names of this protein?
Methyl-accepting chemotaxis protein CtpM.
What is the protein family that this protein belongs to?
Belongs to the methyl-accepting chemotaxis (MCP) protein family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RN19B_XENLA
Sequence: MRLRNDCLVRLLTSWFGIFCLYEMTEGSAEPPPCPGARRRRLLLSLPNVFPGRTRAAPEPSVPSPPPSPPPPPPPPVSVPPPPSSPGGSESLIECPLCLVRQPPEEIPELLSCRHRSCLRCLRQYLRIEICESRVNLRCPECAERLSPQHVRAILRDPLLTRKYEEFLLRRCLAADPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGCRTEFCYHCKHVWHPNQTCDMARQQRAPSLGVRRKHPSGISYGQESGSADDMKSCPRCSAYIIKMNDGSCNHMTCSVCGCEFCWLCMKEISDLHYLSPSGCTFWGKKPWSRKKKIIWQLSTLIGAPVGISLIAGIAIPAMVIGIPVYVGRKIHGRFENKKTSRHKKNLAVTGGVILSVIASPVVAAVSVGIGVPIMLAYVYGVVPVSLCRGGGCGVTTANGKGVKIDFEEDGPITVADAWRALKNPSIGESSMEGLTSVLSTSGSPTDGLSVLQGNYSETASFAALAGGTLTGGMLSGGRAKYCRLEVQADVQKETCQKDSVSLGAVSDSASTRAMAGSIISSYNPQEREVNNMEIQVHIEAKPSRYQLMSESSTEESLHASAPLVESEDAEACRNQVAACDITLAQPESIRSDLESSDAQSDDVPDLASEEYDSPHLFPPSPSNALQESPPHRMCAQEEGLCAHEESLSKVEIIELRV
What is the function of this protein?
E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as UCKL1.  Involved in the cytolytic activity of natural killer cells and cytotoxic T-cells.  Protects against staurosporin-induced cell death (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF19B, RING finger protein 19B.
What is the protein family that this protein belongs to?
Belongs to the RBR family. RNF19 subfamily.
What are the subcellular locations of this protein?
Cytoplasmic granule membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RL16_BREBN
Sequence: MLTPKRVKHRKQHRGKMAGNAKGGTTVAFGEYGLQAMEPSWVTNRQIEAARIAMTRYIKRGGKVWIKIFPDKPVTQKPLEVRMGSGKGSPEKWVAVVKPGKIMFELAGVPEEVAREAMRLAMHKLPIKCKFVKREEVGGDAHEG
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: RECR_TRIL1
Sequence: MLQHAPTLTRLVGELKKLPGIGERTALRLAFHLLKSPQNLGSLAEALTQVQERVCACSVCFALTEQNPCPICSGGRDSSVICVVETSQDMLALERSNAYHGSYHVLQGAISPLHGVNPDDLRIRELLMRIEQGKVEEVVIATNFTVEGETTALYLARQLKPLGIRVTRLAHGIPLGSDIEFVDPATVQWAMKGRSEL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: SOTB_ECOL5
Sequence: MTTNTVSRKVAWLRVVTLAVAAFIFNTTEFVPVGLLSDIAHSFHMQTAQVGIMLTIYAWVVALMSLPFMLMTSQVERRKLLICLFVVFIASHVLSFLSWSFTVLVISRIGVAFAHAIFWSITASLAIRMAPAGKRAQALSLIATGTALAMVLGLPLGRIVGQYFGWRMTFFAIGIGALITLLCLIKLLPLLPSEHSGSLKSLPLLFRRPALMSIYLLTVVVVTAHYTAYSYIEPFVQNIAGFSANFATALLLLLGGAGIIGSVIFGKLGNQYASALVSTAIALLLVCLALLLPAANSEIHLGMLSIFWGIAMMIIGLGMQVKVLALAPDATDVAMALFSGIFNIGIGAGALVGNQVSLHWSMSMIGYVGAVPAFAALIWSIIIFRRWPVTLEEQTQ
What is the function of this protein?
Involved in the efflux of sugars.  The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites.
What are the official names of this protein?
Probable sugar efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL6_ACTPJ
Sequence: MSRVAKAPVNIPAGVEVKLNGQLLTVKGKNGELSREIHNAVEVNQDANALTFVPRTGVANADAQAGTARALVNAMVIGVTEGFTKKLQLVGVGYRAQMKGNVVALSLGYSHPIEHTLPAGVTGECPSQTEIVLKSADKQLIGQVAADIRAYRRPEPYKGKGVRYSDEVVRTKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: ALR_STRP2
Sequence: MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAYGHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFTLTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVCVEGIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVRMGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIATVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNGDKEITATQVATYRVTINYEVVCLLSDRIPREYY
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: FMT_GLOC7
Sequence: MKVVFFGTPQFAVPSLERLLEHSDIDVVAVVTQPDKPRGRGKQLIPSPIKKVALDHQIPIWQPKRVKKNAQTLTKLRETNADAFAVVAYGQILSAEILQMPKLACINVHGSILPKYRGAAPIQWSIYHGETQTGITTMLMDEGMDTGAMLLKAYTPIQLLDNADKIATTLANQGADLLIETLLKLEQGELNPESQNSELATYAPLIQKEDYLINWTRHALQIHNQVRGFYPNCFTTFREQPLKILATAPLGEAYWEHLPSNIAQKIQPQWTTLSSLTSSPGEVVNLIKNLGPIVQTGEGLLLLLQVQLSGKRPQSGWDFVNGTRLSVGEKFLMV
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: GDL51_ARATH
Sequence: MAKNRNLVFFLGVLASFTLSSFPVTVSGEPPILFTFGDSSYDVGNTKFFSSEFDPATTWPYGDSIDDPSGRWSDGHIVPDFVGRLIGHREPIPPVLDPKADLSRGASFAIAGAVVLGSQSTTASMNFGQQISKFLELHKQWTDKERAEAIYMVNIGAEDYLNFAKAHPNANTVEQLTQVAHVLQRIPRELTSLYRAGGARKFAVQNLGPLGCLPIVRQEFKTGENCMEMVNFMVKTHNERLSRLLVAITVPLLYRGFRYSLFDFNGEILRRINEPSLHGYTDTTTSCCGTGSRNAYGCGYSNVHAKLCSYQKSFLFFDGRHNTEKTDEEVANLFYSGDKHVVSPMNIKDLVGKAATDLLAQEI
What are the official names of this protein?
GDSL esterase/lipase At3g14220, Extracellular lipase At3g14220.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL13_STRMK
Sequence: MSTFTAKNETVQRDWYLVDAEGKTLGRLATELARRLRGKHKPVYTPHVDTGDYLVVINAEKIAVTGKKLQDKMYHRFTGYIGNLKTESLAQALERHPERVIEIAVKGMLPKGPLGRQMYRKLKVYAGTEHPHAAQQPQVLDI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: NDPA1_VIBVY
Sequence: MSLHLSNVILHQLSKNDQDELMVNYRSESLVNDSSTENLVAELHRVFHSKAGKGFGCFQSDSEFQIWLNELQRGELNFYDFSQKCAVRLKEELAKYPFADEGILVFAEYQSLATDYLFVGILPLNQSLKVTEGLDISATDYLDINKMDIAARIDLSVYEADKESNRYLSYIKGRVGRKVADFFLDFLQAEVGLDSKQQNQVLMQALDDFCTDAKLEKQEVNEYKKQVYEYCNGQIKAGEEVEIRELSGELPPSPSGASFLEFTQEQGYGLEESFPADRGLVRKLTKYVGAGGGLNVSFDSLLLGERIFYDPETDTLTIKGTPPNLRDQLTRNR
What are the official names of this protein?
Nucleoid-associated protein VV1167.
What is the protein family that this protein belongs to?
Belongs to the YejK family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: MBL2_PIG
Sequence: MSLFPSLHLLLLIVMTASHTETENCEDIQNTCLVISCDSPGINGLPGKDGLDGAKGEKGEPGQGLIGLQGLPGMVGPQGSPGIPGLPGLKGQKGDSGIDPGNSLANLRSELDNIKKWLIFAQGKQVGKKLYLTNGKKMSFNGVKALCAQFQASVATPTNSRENQAIQELAGTEAFLGITDEYTEGQFVDLTGKRVRYQNWNDGEPNNADSAEHCVEILKDGKWNDIFCSSQLSAVCEFPA
What is the function of this protein?
Calcium-dependent lectin involved in innate immune defense.  Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway.  Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages.  According to some authors, it only binds mannose (PubMed:8602463).
What are the official names of this protein?
Mannose-binding protein C, MBP-C, 27 kDa mannan-binding protein monomeric subunit, pMBP-27, Mannose-binding lectin, MBL.
What are the subcellular locations of this protein?
Secreted.
Protein: RL38_NEUCR
Sequence: MPQEIGDIKKFIEICRRKDASAARIKKNKATQQIKFKVRCQKYLYTLVLKDSDKAEKLKASLPPSLTIADVAKRNKKQTA
What are the official names of this protein?
60S ribosomal protein L38.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL38 family.