PharMolix/UniProtQA huggingface dataset:
Protein: TMCAL_STAAB
Sequence: MKSVGLITEYNPFHNGHQYHINQSKKLTNADVTIAIMSGNFVMRGEPAIYNKFTRAKMALSTADLVIELPATASLSSGDHFAELAVKVADYMSVDTIAFGSENNDIKTLKQLAHSINEIEQSESFSQKVKEGKSYPRIISELLEHHEALASPNNILGISYLKAIAKHAKNINAISIKRENAQHHDSLIQHHQFASGTSIRTSIISQDDHWHHVVPKDIQHLYVTPHITLNQIFPYLKYQIIAMTTESLKNIYTVNEGFENRLKSTINEATDFHHFVKSLKTKRYTYTHIQRLLMNVLLNIKPTDVTRNIRAVKVLAMNDRGRQYLKHLKTAFPERQYITNINKSNAHYFTNEIKATHIYNAISGQQQTDFNTPVIQQYR
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YNY3_SCHPO
Sequence: MQKLLLDPALRNWVLLPIMFVMILIGILRHNATILLQSSPKKLSKEEIREQRLLQRAYALRACSNSLLPESIEARKCFLIESLKSGKYLKPVDPNAPKAANPLMDDKTLEGLMESMKGNMLMVVPQTIIMTWINEFFSGFILLKLPFPLTLRFKSIFQSGVATQDLDVQWVSSISWYFLNLFGLKSVYALLLGENNAASNATNEMGMAGFSSAAATAQLIQPGQDISKMMLSEAENVQILKNESLLVDVEKRLLAQFA
What are the official names of this protein?
ER membrane protein complex subunit 3.
What is the protein family that this protein belongs to?
Belongs to the EMC3 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Multi-pass membrane protein.
Protein: VSP1_BOTJR
Sequence: VLGGDECDINEHPFLAFLYSHGYFCGLTLINQEWVVTAAHCDSTNFQMQLGVHSKKVLNEDEQTRNPKEKFICPNKNMSEVLDKDIMLIKLDKPISNSKHIAPLSLPSNPPSVGSVCRIMGWGSITIPNETYPDVPYCANINLVDYEVCQGAYNGLPAKTTLCAGVLEGGKDTCVGDSGGPLICNGQFQGIVSYGAHSCGQGPKPGIYTNVFDYTDWIQRNIAGNTDATCPP
What is the function of this protein?
Thrombin-like enzyme that shows clotting activity upon human plasma.  Shows specific fibrinogenolytic activity for Aalpha chain (FGA).  Hydrolyzes fibrin, BAPNA and TAME, as well as chromogenic artificial substrates of the blood coagulation cascasde: S-27654 for factor X (F10), S-2302 for kallikrein (KLK), factor XIa (F11), and XIIa (F12), and S-2266 for kallikrein and factor XIa (F11).  Subcutaneous injection into mice induces a mild edema.  Intravenous and intramuscular injection reduce plasma fibrinogen concentration and increase the levels of fibrin(ogen) degradation products.  Intramuscular injection also promotes an increase in the expression of proMMP-9, but is unable to activate it.
What are the official names of this protein?
Thrombin-like enzyme BjussuSP-1, SVTLE BjussuSP-1, Fibrinogen-clotting enzyme, Jararacussin-I, Snake venom serine protease 1, SVSP, Thrombin-like enzyme BjussuSP-I, SVTLE BjussuSP-I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: AROE_RHIEC
Sequence: MDDSRETLGPNAFVTGFPIKHSRSPLIHGYWLKTLGLPGSYRAHEVAPDAFPDFIASLKDGSSDFIGGNVTIPHKELAFRLADKPDDLAHELGASNTLWLEDGLLHATNTDGRGFTANLDERHPGWDRHDTAVVFGAGGASRAIIQAVRDRGFREIHVVNRTVERARELADRFGPKVRAHPVGALAEVMHGAGLFVNTTSLGMDGEAAPLIDFAPLAADAVVTDIVYIPLNTPILRQAEEQGLSVVDGLGMLLHQAVPGFEKWFGERPVVDAALRALIVADMEVH
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: THII_YERE8
Sequence: MKFIIKLFPEITIKSQSVRLRFIKILTTNIRNVLKNLEDDTLAVVRHWDHIEIRTKDDNLGPQICDALTRVPGIHHILEVEDRSYTDMHNIFEQTLEAYRETLIGKTFCVRVKRRGKHEFSSGDVERYVGGGLNQHIESAKVKLTHPQVTVHLEIDQDKLTLIKARHEGLGGFPIGTQEDVLSLISGGFDSGVSSYMLMRRGCRVHYCFFNLGGSAHEIGVKQVAHYLWNRFGSSHRVRFVAIDFEPVVGEILEKVEDGQMGVVLKRMMVRAASQVAERYGVQALVTGEALGQVSSQTLTNLRLIDNASDTLILRPLISHDKEHIINLAREIGTEDFAKTMPEYCGVISKSPTVKAVKAKIEEEESHFDFSILDRVVNEAKNVDIREIAAQSREQVVEVETVAELADTDVLLDIRAPDEQDEKPLKLDGIEVRTLPFYKLSTQFADLDQSKSYLLYCDRGVMSRLQALYLREQGYTNVKVYRP
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_PARUW
Sequence: MIITIDGPVATGKSTIAKKLAESIGFIFFDTGAMYRALTFGILKNQIDLSDPDTLQNYLDHFQFDIKVIHHDRHYFVDKEDVSKLIRGKEVTSSVSKVSAIKAVREKLMAIQRELAEGVNAVFEGRDMGTVVFPNANIKIFLTGRNDVRAKRRYDELTSKFPEETKELTLEKCLEEITKRDNYDSTREYSPLCQAEDAFVIDTSDLSIDEVVYKILEYKDTIKTKRPS
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAY_THEVB
Sequence: MLERPPMPSTKTTAAIEPRWRAGQRLFRLLAIGLLIVTIAYDTGANHWQQPLQTLTLPWLVSFALVAVLGMAVVPLLRRLKTGQIIREDGPQSHLQKSGTPTMGGIFFVPTGLGLAFLWTGFAQGKLSPTVGAIALLVLWYAAIGWWDDWQVLRRQSNKGLSARLRLLLEGIGAALFCAWLVASDPTATVVTAPWGWVWPLGMAFIPLAIFVPMAEGNALNLTDGLDGLAGGTGAIALLTLGIILSPYPDLQILAVVMSGACLGFLWHNHHPARVFMGDTGSLALGAVLAGIGLASHHLWELLIVSGLFFVESLSVIAQVLYYKATKGPDGVGKRLLRMAPLHHHFELGGWSELRIVRTFYGVVALLGLLCVLLQWLA
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RB18B_DANRE
Sequence: MDDDVLTTLKILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTIAIDGNRAKLAIWDTAGQERFRTLTPSYYRGAQGVILVYDVTKRDTFTKLENWLNELETYCTRNDLVKMLVGNKIDKDNREVDRNEGLKFARKHSMLFIEASAKTRDGVQCAFEELVEKILQTPGLWESSIQNHGVQLSDNEPQRQGACGGYCSLV
What is the function of this protein?
Required for the localization of ZFYVE1 to lipid droplets and for its function in mediating the formation of endoplasmic reticulum-lipid droplets (ER-LD) contacts (By similarity).  Plays a role in apical endocytosis/recycling (By similarity).  Plays a key role in eye and brain development and neurodegeneration (PubMed:21473985).
What are the official names of this protein?
Ras-related protein Rab-18-B.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Apical cell membrane. Lipid droplet.
Protein: LYSC3_PIG
Sequence: MKTLLVLALLLLSVSVQAKVYDRCEFARILKKSGMDGYRGVSLANWVCLAKWESNFNTKATNYNPGSQSTDYGIFQINSRYWCNDGKTPKAVNACHISCKVLLDDDLSQDIECAKRVVRDPQGIKAWVAWKAHCQNKDVSQYIRGCKL
What is the function of this protein?
Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.
What are the official names of this protein?
Lysozyme C-3, 1,4-beta-N-acetylmuramidase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
What are the subcellular locations of this protein?
Secreted.
Protein: U2A2A_ORYSJ
Sequence: MAEHEEQPYEGNGNGGDPAPASAYAEYPAPEGSPPAAAAKPTGFSDGATDGGRSQHETQPHDGRSSKSRERERERDKDKERDRDRDRDRRDRDRGDKDRDRDRHREHRDRSERREHHDRERSDDRDRRRGHDSERRRDRDRDGHRRHRSRSRSPSKGRDRRSRSRSRSRSSKRVSGFDQGPQAAIPALAAGAAPGQVPVVAPAISGMLPNMFNLTQTPFTPLVIQPQAMTQQATRHARRVYVGGLPPTANEHTVAVYFNQVMAAVGGNTAGPGDAVLNVYINHDKKFAFVEMRSVEEASNAMALDGIMFEGAPVKVRRPTDYNPSLAAALGPSQPNPNLNLAAVGLTPGSAGGLEGPDRIFVGGLPYYFTEAQVRELLESFGPLRGFDLVKDRETGNSKGYAFCVYQDLNVTDIACAALNGIKMGDKTLTVRRANQGASQPRPEQESMLLHVQQQAQMQKLMFQVGGGALPTKVVCLTQVVSPDELRDDEEYEDIVQDMREEGCRYGNLVKVVIPRPDPSGAPVAGVGRVFLEFADVESSTKAKNGMHGRKFANNQVVAVFYPEDKFAEGQYDG
What is the function of this protein?
Necessary for the splicing of pre-mRNA.
What are the official names of this protein?
Splicing factor U2af large subunit A, U2 auxiliary factor 65 kDa subunit A, U2 small nuclear ribonucleoprotein auxiliary factor large subunit A, U2 snRNP auxiliary factor large subunit A.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CIPK5_ARATH
Sequence: MEEERRVLFGKYEMGRLLGKGTFAKVYYGKEIIGGECVAIKVINKDQVMKRPGMMEQIKREISIMKLVRHPNIVELKEVMATKTKIFFVMEFVKGGELFCKISKGKLHEDAARRYFQQLISAVDYCHSRGVSHRDLKPENLLLDENGDLKISDFGLSALPEQILQDGLLHTQCGTPAYVAPEVLKKKGYDGAKADIWSCGVVLYVLLAGCLPFQDENLMNMYRKIFRADFEFPPWFSPEARRLISKLLVVDPDRRISIPAIMRTPWLRKNFTPPLAFKIDEPICSQSSKNNEEEEEDGDCENQTEPISPKFFNAFEFISSMSSGFDLSSLFESKRKVQSVFTSRSSATEVMEKIETVTKEMNMKVKRTKDFKVKMEGKTEGRKGRLSMTAEVFEVAPEISVVEFCKSAGDTLEYDRLYEEEVRPALNDIVWSWHGDNNNTSSEDC
What is the function of this protein?
CIPK serine-threonine protein kinases interact with CBL proteins.  Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner (By similarity).
What are the official names of this protein?
CBL-interacting serine/threonine-protein kinase 5, SNF1-related kinase 3.24, SOS2-like protein kinase PKS19.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
Protein: CAPSD_HPBDC
Sequence: MDINASRALANVYDLPDDFFPKIDDLVRDAKDALEPYWKSDSIKKHVLIATHFVDLIEDFWQTTQGMHEIAESLRAVIPPTTAPVPTGYLIQHEEAEEIPLGDLFKHQEERIVSFQPDYPITARIHAHLKAYAKINEESLDRARRLLWWHYNCLLWGEANVTNYISRLRTWLSTPEKYRGRDAPTIEAITRPIQVAQGGRKTSSGTRKPRGLEPRRRKVKTTVVYGRRRSKSRERRAPSPQRAGSPLPRSSSSHHRSPSPRK
What is the function of this protein?
Self assembles to form an icosahedral capsid.  Most capsid appear to be large particles with an icosahedral symmetry of T=4 and consist of 240 copies of capsid protein, though a fraction forms smaller T=3 particles consisting of 180 capsid proteins.  Entering capsid are transported along microtubules to the nucleus.  Phosphorylation of the capsid is thought to induce exposure of nuclear localization signal in the C-terminal portion of the capsid protein that allows binding to the nuclear pore complex via the importin (karyopherin-) alpha and beta.  Capsids are imported in intact form through the nuclear pore into the nuclear basket, where it probably binds NUP153.  Only capsids that contain the mature viral genome can release the viral DNA and capsid protein into the nucleoplasm.  Immature capsids get stucked in the basket.  Capsids encapsulate the pre-genomic RNA and the P protein.  Pre-genomic RNA is reverse transcribed into DNA while the capsid is still in the cytoplasm.  The capsid can then either be directed to the nucleus, providing more genome for transcription, or bud through the endoplasmic reticulum to provide new virions (By similarity).
What are the official names of this protein?
Capsid protein, Core antigen, Core protein, HBcAg.
What is the protein family that this protein belongs to?
Belongs to the avihepadnavirus core antigen family.
What are the subcellular locations of this protein?
[Capsid protein]: Virion. Host cytoplasm.
Protein: ATPE_JANMA
Sequence: MAHTMRVDVVSAEEEIFSGEAEFVALPGESGELGILPGHTPLITRIRPGAVRIKVTGQAEDEFVFVAGGILEVQPHVVTVLADTAIRGGDLDEAKAAEAKQLAEEALVNKESKIDYAQAQAELASAIAQLAAIQRLRQKR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: VMA21_ASPFU
Sequence: MTSRRSQEKSYAEAAAAPPPKESASSDVTPAVPADVIYKLLGFTAAMVVGPIGMYFVTVNSGGMSFFHQTSNFSLFETLTRIASPTVAGITAAITANLVLFGYIYVAWLDDREEREAASKRNEKKAQ
What is the function of this protein?
Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.
What are the official names of this protein?
Vacuolar ATPase assembly integral membrane protein vma21.
What is the protein family that this protein belongs to?
Belongs to the VMA21 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein.
Protein: RPOZ_PSEMY
Sequence: MARVTVEDCLDNVDNRFELVMLATKRSRQLATGGKEPKVAWENDKPTVVALREIAAGLVDYEVVAQEDIVEEEPLFAAFEEEANEPL
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: RD21L_MOUSE
Sequence: MFYTHVLMSKRGPLAKIWLAAHWEKKLTKAHVFECNLEITIQKIISPKVKIALRTSGHLLLGVVRIYNRKAKYLLADCSEAFLKMKMTFRPGLVDLPKENFEAAYNTITLPEEFHDFEIYNINEIDISEPLAQNQSRPEEITLREEYSNDLLFQAGSFGDEPEILRRHSFFDDNILMNSSGLVVEHSSGSFAEEKSLFFDNGDGFGDEGAAGEMIDNLLQDESTFLEEAYLNKEVSLPPELPSSIMVEPGNSDDQCIPEDEEINEITLLSNEDEGFTLDPIDDLDIADRRRRKKRRLLVDPVKEISSKAMHRQLASFMDTLMVLDLAPPTQRLMMWKKRGGVDMLLSTATQDLINDELKMLFTKCFLSSDYKLAKLTLKESVRKEVGNQQIAEPSVMGEPNSHSELDQPQDWKDVTDESVGSFQENVNMNVNSEQDILGMISPAVEGLSSMNGSLAQENCPAELESSGSKQNTEAEKWNQRLFQTLNVLREFNKMGMQSFSLKKLCRNSDRKQAAAKFYTLLILKKHRAIELSQSVPYADIIATVGPMFYKM
What is the function of this protein?
Meiosis-specific component of some cohesin complex required during the initial steps of prophase I in male meiosis.  Probably required during early meiosis in males for separation of sister chromatids and homologous chromosomes.  Replaces RAD21 in premeiotic S phase (during early stages of prophase I), while RAD21 reappears in later stages of prophase I.  Involved in synaptonemal complex assembly, synapsis initiation and crossover recombination between homologous chromosomes during prophase I.  Not required for meiosis in females in young mice, while it is required later as mice age.
What are the official names of this protein?
Double-strand-break repair protein rad21-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the rad21 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=In meiotic chromosomes, localized along axial elements in early meiosis: detectable on the axial elements in leptotene, and stays on the axial/lateral elements until mid pachytene. It then disappears and is replaced with RAD21. Compared to REC8, has mutually exclusive loading sites on the chromosomes: REC8 and RAD21L form distinct cohesin-enriched domains along the axial elements.
Protein: SYI_ANAMM
Sequence: MNYYPEVKGNPEFSAIEKEILQYWNSEKIFEESVNTRSRDRSFVFYDGPPFANGLPHYGHLLTGFIKDAVARYKTMRGFRVERKFGWDCHGLPAEMLAEKELGVSGKVSIESFGIDKFNDYCRSSIMRFTQQWREYVERQGRWVDFENGYRTMDKSFMESVMWAFHELWHKGLVYESVKVVPYSWACQTPLSNFETKMDNAYREKVSKSVTVRFKLSEQVGFVPQGVESCSILAWTTTPWTLVSNFALAINTNMDYVGAVVGAEMLIFSAGYLDHFMRYCERHSLECAKVVQIPAKELLAVKYMPPFPYFADSKNAFMVLDAEFVAEGAGTGIVHLAPGFGEDDFLLCKQHGIPNLGEESRGMLSVICPIDDAGRFTAAVGDFAGQHVFDVVDAVIRQLKEKGLWFATEQCTHSYPHCWRTDTPLIYRATSSWYVEVTKLKARMVELNKEVNWVPEHVQSGQFGKWLDGAKDWSVSRHRFWGAPVPVWRSDDPKYPRTDVYGSIKKVLPDVKALEEDFGPVEDLHRPYIDNLVRPNPDDPTGKSMMRRVPDVLDCWFESGSMPYAQMHYPFENKEFFDSHFPADFITEYIAQTRGWFYTLFVLSTGLFDRHPFKNCICHGVVLDIKGQKLSKRLNNYPDPMEMFEKYGADSVRFTMLSHAVSIGGDLLLDQDGDVVRDTLKSVVKPIWNSYSFFTVYANSDQMQGRILESLEGITNIMDQYILYECACMVVKVLEAMESSSAGVRDPYNIRLACAAIVQFSDKLNNWYIRGCRGRFWMRDKTADKSDAYNTLYTVLYHLARTIAPFLPFIAESIWLGLSFQREKSVHLADFPDASSFSAVHQYKKNAEYMQLAMDVCSHVLSLRNAHNIRVRQPLRRMVVYPYNCESLLDMPQQYRDIILNEVNVKSLQIASTIGDMASFELKLNFALLGQRVPEKVKQIITLARAGVWEVQSDGSLLLGAPGCEQCVIQKDEFSLNLKVHSEYACQIISGGVPVGVLHIDHELTRELLLEGIARDVMRLIQQARKDCGLEMLDHAEVIINTDAAEIIEAISIWYDFIKQQTFSHTLEHRPAQAVVEDCSKYTKISGKDFDIFLCKSALCS
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSTB2_SYNJB
Sequence: MQTQSLNQTSYVFRTENLNVYYGSNLAVKNVTLDIPARQITAFIGPSGCGKSTILRCFNRTNDLIPGARVEGKLTYHGKDLYAKEVDPVAVRRRIGMVFQRPNPFPKSIYDNVAYGPRVLGMKVDLDEVVETSLKRAALWDEVKDKLKENGQSLSGGQQQRLCIARALAVQPDVILMDEPCSALDPISTRRIEELMKELEEEYTIIIVTHNMQQASRVSDMTAFFSVELVGSNRVGELIEFDRTEVIFNSPTKQATRDYVEGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB 2, ABC phosphate transporter 2, Phosphate-transporting ATPase 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: UB2V2_XENLA
Sequence: MAVCAGIKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYENRIYSLRLECGPKYPEAPPTVRFVTKMNMNGINNSNGTVDYRSIPVLAKWQNSFSIKVLLQELRRLMMSKENMKLPQPPEGQTYNN
What is the function of this protein?
Has no ubiquitin ligase activity on its own.  The ube2v2/ube2n heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'.  This type of poly-ubiquitination does not lead to protein degradation by the proteasome.  Mediates transcriptional activation of target genes.  Plays a role in the control of progress through the cell cycle and differentiation.  Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage (By similarity).
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 variant 2.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: TXP1_BRAAI
Sequence: ILECVFSCDIKKEGKPCKPKGEKKCTGGWRCKIKLCLKI
What is the function of this protein?
Inhibits voltage-gated calcium channels (Cav) in rat cerebellar granule cells (By similarity).  Has insecticidal activity to crickets (Acheta domesticus) (PubMed:19374957).  Is not toxic to mice (PubMed:19374957).
What are the official names of this protein?
Omega-theraphotoxin-Ba1a, Omega-TRTX-Ba1a, Ba1.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 12 (Hwtx-2) family. 06 (TXP1) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LHX5_MOUSE
Sequence: MMVHCAGCERPILDRFLLNVLDRAWHIKCVQCCECKTNLSEKCFSREGKLYCKNDFFRRFGTKCAGCAQGISPSDLVRKARSKVFHLNCFTCMVCNKQLSTGEELYVIDENKFVCKDDYLSSSSLKEGSLNSVSSCTDRSLSPDLQDPLQDDPKETDNSTSSDKETANNENEEQNSGTKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMKQLSALGARRHAFFRSPRRMRPLGGRLDESEMLGSTPYTYYGDYQSDYYAPGGNYDFFAHGPPSQAQSPADSSFLAASGPGSTPLGALEPPLAGPHGADNPRFTDMISHPDTPSPEPGLPGALHPMPGEVFSGGPSPPFPMSGTSGYSGPLSHPNPELNEAAVW
What is the function of this protein?
Plays an essential role in the regulation of neuronal differentiation and migration during development of the central nervous system.
What are the official names of this protein?
LIM/homeobox protein Lhx5, LIM homeobox protein 5.
What are the subcellular locations of this protein?
Nucleus.
Protein: PYRC_ACET2
Sequence: MLIKGGHVVDPKTNTNGIMDILVEDGIITEIGKDIEISNGDIIYAEGKLVLPGLVDAHCHLRDPGFEYKEDIETGTMSAAMGGFTSIACMPNTDPVCDNKAVVKYIINKAKQDGYVNVYPIGAISKGQKGEELSEIGELKFAGAVAISDDGKPVKSSSLMKRALEYSSMFDIAVISHCEDLDLADGGVMNEGYWSTVMGLKGIPSAAEEIMVARDIILSEYTKVPIHIAHVSTELSVELIRNAKKRGVKVTCETCPHYFVLTDEACKDFNTLAKVNPPLRTRRDVEAVIEGLKDGTIDIIATDHAPHHADEKNVEFNLAANGMVGFETALPLAITYLVKPGHLTISQLVEKMCVNPSKLLGINKGTLETGRSADITIVDLNEEFVVDVNKFKSKSKNSPFHGFKLNGSVYYTLVNGNVVVREKVLL
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: CITEL_MYCTU
Sequence: MNLRAAGPGWLFCPADRPERFAKAAAAADVVILDLEDGVAEAQKPAARNALRDTPLDPERTVVRINAGGTADQARDLEALAGTAYTTVMLPKAESAAQVIELAPRDVIALVETARGAVCAAEIAAADPTVGMMWGAEDLIATLGGSSSRRADGAYRDVARHVRSTILLAASAFGRLALDAVHLDILDVEGLQEEARDAAAVGFDVTVCIHPSQIPVVRKAYRPSHEKLAWARRVLAASRSERGAFAFEGQMVDSPVLTHAETMLRRAGEATSE
What is the function of this protein?
May play a role in fatty acid biosynthesis.
What are the official names of this protein?
Citrate lyase subunit beta-like protein.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit-like subfamily.
Protein: DCUP_WOLTR
Sequence: MKEESELARIKSSKAVVSKTIKEGKQGRKIPIWLMRQAGRSLPEYRRAVKDTSSFMEICYNTDLVVELTLQPVARFSMDAAIIFSDILIVADVLGCDVDFIRGVGPTIKPVKNFKELRNPQKIETKTLPILNAIRKVRDKLPEEKSLIGFAGGPWTVASYIIEGRSSKTFSKVLNLHPSSLEQIIEQITEVTISYLVKQIEFGADVIQLFDSNAGVLSGELFEECVIKPTKKIVSAIKGKFPDFPIIGFPKSAGSLYKDYCEKTGVSAVSIDYNVPIEWAKENLKIPLQGNLNPSLLAYNKMEAIKETKRIIDCFRDLPFIFNLGHGVLPNTPIENIAALVDLVKSQ
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QCRC_MYCTO
Sequence: MTKLGFTRSGGSKSGRTRRRLRRRLSGGVLLLIALTIAGGLAAVLTPTPQVAVADESSSALLRTGKQLFDTSCVSCHGANLQGVPDHGPSLIGVGEAAVYFQVSTGRMPAMRGEAQAPRKDPIFDEAQIDAIGAYVQANGGGPTVVRNPDGSIATQSLRGNDLGRGGDLFRLNCASCHNFTGKGGALSSGKYAPDLAPANEQQILTAMLTGPQNMPKFSNRQLSFEAKKDIIAYVKVATEARQPGGYLLGGFGPAPEGMAMWIIGMVAAIGLALWIGARS
What is the function of this protein?
Cytochrome b subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis.  The bc1 complex catalyzes the oxidation of ubiquinol and the reduction of cytochrome c in the respiratory chain.  The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
What are the official names of this protein?
Cytochrome bc1 complex cytochrome c subunit, Cytochrome bc1 reductase complex subunit QcrC, Ubiquinol--cytochrome c reductase cytochrome c subunit.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.