PharMolix/UniProtQA huggingface dataset:
Protein: HEM3_HELP2
Sequence: MGNLVIGSRGSELALWQANHIKERLKKECLIESEIQIVKTKGDKILDTPLNKIGGKGLFTKELEELLLKGTIDLAVHSLKDVPVVFEKGLDLACITKRADVRDTFLSVKFPDLMSLPKGAKVGTTSLRRSMQLKLKRQDLDTESLRGNVQTRLKKLECGEFDAIILAEAGLCRLEIQGAKYRKAFSVKEMIPSMGQGALGVEMLKNHKHFATLQKLNDEKSAFCCRLEREFIKGLNGGCQIPIGVHASLMGDRVKIQAVLGLPNGKEVITKEKRGDKTKAFDLVQELLEEFLQSGAKEILEKAQLF
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: ADCY2_RAT
Sequence: MRRRRYLRDRAEAAAAAAAGGGEGLQRSRDWLYESYYCMSQQHPLIVFLLLIVMGACLALLAVFFALGLEVEDHVAFLITVPTALAIFFAIFILVCIESVFKKLLRVFSLVIWICLVAMGYLFMCFGGTVSAWDQVSFFLFIIFVVYTMLPFNMRDAIIASILTSSSHTIVLSVYLSATPGAKEHLFWQILANVIIFICGNLAGAYHKHLMELALQQTYRDTCNCIKSRIKLEFEKRQQERLLLSLLPAHIAMEMKAEIIQRLQGPKAGQMENTNNFHNLYVKRHTNVSILYADIVGFTRLASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLPISLPNHAKNCVKMGLDMCEAIKKVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHISSVTLEHLNGAYKVEEGDGEIRDPYLKQHLVKTYFVINPKGERRSPQHLFRPRHTLDGAKMRASVRMTRYLESWGAAKPFAHLHHRDSMTTENGKISTTDVPMGQHNFQNRTLRTKSQKKRFEEELNERMIQAIDGINAQKQWLKSEDIQRISLLFYNKNIEKEYRATALPAFKYYVTCACLIFLCIFIVQILVLPKTSILGFSFGAAFLSLIFILFVCFAGQLLQCSKKASTSLMWLLKSSGIIANRPWPRISLTIVTTAIILTMAVFNMFFLSNSEETTLPTANTSNANVSVPDNQASILHARNLFFLPYFIYSCILGLISCSVFLRVNYELKMLIMMVALVGYNTILLHTHAHVLDAYSQVLFQRPGIWKDLKTMGSVSLSIFFITLLVLGRQSEYYCRLDFLWKNKFKKEREEIETMENLNRVLLENVLPAHVAEHFLARSLKNEELYHQSYDCVCVMFASIPDFKEFYTESDVNKEGLECLRLLNEIIADFDDLLSKPKFSGVEKIKTIGSTYMAATGLSAIPSQEHAQEPERQYMHIGTMVEFAYALVGKLDAINKHSFNDFKLRVGINHGPVIAGVIGAQKPQYDIWGNTVNVASRMDSTGVLDKIQVTEETSLILQTLGYTCTCRGIINVKGKGDLKTYFVNTEMSRSLSQSNLAS
What is the function of this protein?
Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling (PubMed:22906005, PubMed:24363043, PubMed:10427002, PubMed:1719547, PubMed:7761832, PubMed:21596131, PubMed:11087399, PubMed:15591060, PubMed:19243146, PubMed:16766715).  Down-stream signaling cascades mediate changes in gene expression patterns and lead to increased IL6 production (PubMed:24363043).  Functions in signaling cascades downstream of the muscarinic acetylcholine receptors (PubMed:22906005).
What are the official names of this protein?
Adenylate cyclase type 2, ATP pyrophosphate-lyase 2, Adenylate cyclase type II, Adenylyl cyclase 2, AC2.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasm.
Protein: NLPI_SHIBS
Sequence: MKPFLRWCFVATALTLAGCSNTSWRKSEVLAVPLQPTLQQEVILARMEQILASRALTDDERAQLLYERGVLYDSLGLRALARNDFSQALAIRPDMPEVFNYLGIYLTQAGNFDAAYEAFDSVLELDPTYNYAHLNRGIALYYGGRDKLAQDDLLAFYQDDPNDPFRSLWLYLAEQKLDEKQAKEVLKQHFEKSDKEQWGWNIVEFYLGNISEQTLMERLKADATDNTSLAEHLSETNFYLGKYYLSLGDSDSATALFKLAVANNVHNFVEHRYALLELSLLGQDQDDLAESDQQ
What is the function of this protein?
May be involved in cell division.  May play a role in bacterial septation or regulation of cell wall degradation during cell division (By similarity).
What are the official names of this protein?
Lipoprotein NlpI.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: DDX6_PONAB
Sequence: MSTARTENPVIMGLSSQNGQLRGPVKPTGGPGGGGTQTQQQMNQLKNTNTINNGTQQQAQSMTTTIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRGDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINLMEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGGSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYVAEYHSEPVEDEKP
What is the function of this protein?
Essential for the formation of P-bodies, cytosolic membrane-less ribonucleoprotein granules involved in RNA metabolism through the coordinated storage of mRNAs encoding regulatory functions.  Plays a role in P-bodies to coordinate the storage of translationally inactive mRNAs in the cytoplasm and prevent their degradation.  In the process of mRNA degradation, plays a role in mRNA decapping.  Blocks autophagy in nutrient-rich conditions by repressing the expression of ATG-related genes through degradation of their transcripts.
What are the official names of this protein?
Probable ATP-dependent RNA helicase DDX6, DEAD box protein 6.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Cytoplasm. Nucleus. Note=Imported in the nucleus via interaction with EIF4ENIF1/4E-T via a piggy-back mechanism. Upon cellular stress, relocalizes to stress granules.
Protein: PROF_BETVU
Sequence: YMVIQGEPGAVIRLGDYLIDQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity).
What are the official names of this protein?
Profilin, Pollen allergen Beta v 2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: Y1642_CAMJE
Sequence: MDFSKMGELLNQVQEKAKNIELELANREFSAKSGAGLVKVSANGKGEIIDVSIDDSLLEDKESLQILLISAINDVLAMVAQNRSSMANDVLGGFGGMKL
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Cj1642.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: TBB2_MAIZE
Sequence: MREILHIQGGQCGNQIGSKFWEVVCDEHGIDPTGRYMGTSDVQLERVNVYYNEASCGRFVPRAVLMDLEPGTMDAVRTGPYGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELIDSVLDVVRKEAENCDCLQGFQVCHSLGGGTGSGMGTLLISKIREEYPDRMMMTFSVFPSPKVSDTVVEPYNATLSVHQLVENADECMVLDNEALYDICFRTLKLTTPSFGDLNHLISATMSGVTCCLRFPGQLNSDLRKLAVNLIPFPRLHFFMVGFAPLTSRGSQQYRSLTVPELTQQMWDSKNMMCAADPRHGRYLTASAMFRGKMSTKEVDEQMINVQNKNSSYFVEWIPNNVKSSVCDIPPRGLSMSSTFVGNSTSIQEMFRRVSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEEADYEEEEAAAE
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta-2 chain, Beta-2-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RNE_PORPU
Sequence: MTNTIVISCLHNIAAILYCGQIQKLVVANAHYQVSDIYLGTVDKIFSGINAAFVDLGKNEYSGFIHISDTGPLKKKYYINNITNILTIRQKILVQIIKEPTLNKGPRLTANITLSGRYIVLMPFSQAICISRKIYDEDERHYLKALAILIKPPTMGLLFRPSAIGIDEEIILSELTNLKEQWYFIQKSAINNCAPVLLYKDEDIVKKVIRDFYDNNTKNIVIDSNLGLKQLNYYINTWQCNFSSTIPSLQLYSSNKCILDTFRINQAISRALIPKVDLILGGYMFIETLEAFTIIDVNSGSFNNSTSARETVLKTNCSAATEIAYQLKIRNIAGVIIIDFIDMESQRDQLQLLEHFDKELSLDDAKPQIVQLSELGLVELTRRRKGKSLYELVSNDSNYFHFFIQLEQLDSIKPSSYKSKRLSSSVKSWLFSEIDMINRVFFKKSNLYRLSNFYYARNLYIIYSDFTVNKNIQLAARYKLMYSLQNIQILPSTWYFNFLDIHTNNITNYLS
What is the function of this protein?
Involved in intercistronic processing of primary transcripts from chloroplast operons.  The endonucleolytic activity of the enzyme depends on the number of phosphates at the 5' end, is inhibited by structured RNA, and preferentially cleaves A/U-rich sequences.
What are the official names of this protein?
Ribonuclease E/G-like protein, RNase E/G-like protein.
What is the protein family that this protein belongs to?
Belongs to the RNase E/G family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: ATPE_GOSBA
Sequence: MTLNLCVLTPNRIVWDSEVKEIILSTNSGQIGVLPNHAPIATAVDIGILRIRLNDQWLTMALMGGFARIGNNEITILVNDAEKGSDIDPQEAQQALEIAEANLRKAEGKRQTIEANLALRRARTRVEAINAIS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, chloroplastic, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: Y497_MYCTO
Sequence: MTGPHPETESSGNRQISVAELLARQGVTGAPARRRRRRRGDSDAITVAELTGEIPIIRDDHHHAGPDAHASQSPAANGRVQVGEAAPQSPAEPVAEQVAEEPTRTVYWSQPEPRWPKSPPQDRRESGPELSEYPRPLRHTHSDRAPAGPPSGAEHMSPDPVEHYPDLWVDVLDTEVGEAEAETEVREAQPGRGERHAAAAAAGTDVEGDGAAEARVARRALDVVPTLWRGALVVLQSILAVAFGAGLFIAFDQLWRWNSIVALVLSVMVILGLVVSVRAVRKTEDIASTLIAVAVGALITLGPLALLQSG
What are the official names of this protein?
Uncharacterized protein MT0517.
What is the protein family that this protein belongs to?
To M.leprae ML2433.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPOB_LYSSC
Sequence: MNELTGQLVQYGQHRQRRSFARIKEVLELPNLIEIQTASYEWFLEEGLREMFRDISPIEDFTGNLSLEFIDYSLGDPKYDVDECKERDVTYAAPLRVKVRLYNKETDEVKEQDVFMGDFPLMTETGTFIINGAERVIVSQLVRSPSVYFHDKTDKNGKKGFGATVIPNRGAWLEYETDAKDVVYVRIDRTRKLPVTVLLRALGFGSDQEIIDIIGDNEYLRNTLEKDNSESTEKALLEIYERLRPGEPPTVESAKSLLYSRFFDAKRYDLANVGRYKMNKKLHIKNRLFNQTIAETLVDPETGEILVEKGTVLDRRTLDKILPYLEDSSKGIGFRTLSQVGGVLEDDVTIQSIKIYAPKDEAQKEINIISNAYIDEEVKNITPADVLSSVSYFFNLLYQVGATDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSINDTAAIVPQQLINIRPVIASIKEFFGSSQLSQFMDQTNPLAELTHKRRLSALGPGGLTRERAGFEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSFAKVNKFGFIETPYRRIDHETGQVTDQIDYLTADEEDNYYVAQANSPLNPDGSFANDEVVGRFRGDNTVFNKAQMDYMDVSPKQVVSAATACIPFLENDDSNRALMGANMQRQAVPLLNPEAPFVGTGMEHVDARDSGAAVVAKYDGIVEHVEARSIHVRRIEVVDGKEVKGDLTKYKLQKFIRSNQGTSYNQRPLVKVGERVKPRDILADGPSMEKGELALGRNVLVAFMTWNGFNYEDAVIMSERLVKDDVYTSVHIEEYESESRDTKLGPEEITRDIPNVGEDALRNLDERGIIRIGAEVRDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPHGAGGIILDVKVFNREDGDELPPGVNQLVRAYIVQKRKIRVGDKMAGRHGNKGVISRILPEEDMPFMPDGTPVDIMLNPLGVPSRMNIGQVLELHLGMASRYLGVHMATPVFDGANEEDVWETMEEAGMNRDGKTILYDGRSGEPFDNRVSVGIMYMIKLAHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTVKSDDVVGRVKTYEAIVKGESVPEPGVPESFKVLIKELQSLGMDVKMLTVNDEEVELRDLDEEEDLQPADALNIAPQPDTEEEPVESFE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: SECA_CUPTR
Sequence: MITGLLKKVFGSRNERLIKQYRRTVAQINALEPKFEQLSDDELRGMTEAFRQRHAGGESLEALLPEAFAVCREASKRVMKMRHFDVQLIGGMVLNDNKIAEMRTGEGKTLTATLAVYLNAITGKGVHVVTVNDYLAQRDAEWMGRLYNFLGLSVGVNLSQMAHDQKQAAYNADITYGTNNEFGFDYLRDNMVYDPSQRVQRPLHYAIVDEVDSILIDEARTPLIISGQAENQTDLYQRMNGIPKLLERQIGEEKADGTGVEKPGDYYVDEKGHQVYLTEAGHEKAEEILSQLGLIGEGESLYAPQNITLMHHLYAALRAHSLFHRDQHYVVQNDEVVIVDEFTGRLMTGRRWSDGLHQAVEAKEGVTVQQENQTLATVTFQNYFRMYEKLAGMTGTADTEAYEFQEIYGLEVVVIPTNRPTQRKDLQDQIYKTGKERYDAVVRDIRDCYERGQPVLVGTTSIETSEYLSGLLDREQLPHQVLNAKQHAREAEIVAQAGRPKMITIATNMAGRGTDIVLGGNVEKQAGFIEADPNLSDADKAARIQQLKDEWQSLHEQVKAAGGLHIVGTERHESRRIDNQLRGRAGRQGDPGSSRFYLSLDDQLLRIFAGDRVRAIMERLKMPEGEPIEAGIVTRSIESAQRKVEGRNFDIRKQLLQYDDVANDQRKEIYKLRNDVLEANDVGEMVANLRESVLIELFRDHVPADTMEEQWNIAGLETRLREDWGLEVPLAKTIEGAQSIEDEELLNLIMKAATERYESKVAMVGRESFAGFERSVMLQSIDTHWREHLAALDHLRQGIHLRGYAQKDPKQEYKRESFELFARLLDVIKNEVTRVTFNVQIQSPEELEQASEQIEEGLSHLENVQYKHDEFAEGREPVEEAPSPRTGTAMAAAELALAGMPKVGRNDPCPCGSGKKFKQCHGKLS
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: NRDD_BPT4
Sequence: MTIEKEIEGLIHKTNKDLLNENANKDSRVFPTQRDLMAGIVSKHIAKNMVPSFIMKAHESGIIHVHDIDYSPALPFTNCCLVDLKGMLENGFKLGNAQIETPKSIGVATAIMAQITAQVASHQYGGTTFANVDKVLSPYVKRTYAKHIEDAEKWQIADALNYAQSKTEKDVYDAFQAYEYEVNTLFSSNGQTPFVTITFGTGTDWTERMIQKAILKNRIKGLGRDGITPIFPKLVMFVEEGVNLYKDDPNYDIKQLALECASKRMYPDIISAKNNKAITGSSVPVSPMGCRSFLSVWKDSTGNEILDGRNNLGVVTLNLPRIALDSYIGTQFNEQKFVELFNERMDLCFEALMCRISSLKGVKATVAPILYQEGAFGVRLKPDDDIIELFKNGRSSVSLGYIGIHELNILVGRDIGREILTKMNAHLKQWTERTGFAFSLYSTPAENLCYRFCKLDTEKYGSVKDVTDKGWYTNSFHVSVEENITPFEKISREAPYHFIATGGHISYVELPDMKNNLKGLEAVWDYAAQHLDYFGVNMPVDKCFTCGSTHEMTPTENGFVCSICGETDPKKMNTIRRTCGYLGNPNERGFNLGKNKEIMHRVKHQ
What is the function of this protein?
Catalyzes the conversion of ribonucleotides into deoxyribonucleotides, which are required for DNA synthesis and repair.
What are the official names of this protein?
Anaerobic ribonucleoside-triphosphate reductase, Class III ribonucleoside-triphosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the anaerobic ribonucleoside-triphosphate reductase family.
Protein: PENK_BOVIN
Sequence: MARFLGLCTWLLALGPGLLATVRAECSQDCATCSYRLARPTDLNPLACTLECEGKLPSLKTWETCKELLQLTKLELPPDATSALSKQEESHLLAKKYGGFMKRYGGFMKKMDELYPLEVEEEANGGEVLGKRYGGFMKKDAEEDDGLGNSSNLLKELLGAGDQREGSLHQEGSDAEDVSKRYGGFMRGLKRSPHLEDETKELQKRYGGFMRRVGRPEWWMDYQKRYGGFLKRFAEPLPSEEEGESYSKEVPEMEKRYGGFMRF
What is the function of this protein?
Enkelytin possesses antibacterial activity against Gram-positive bacteria such as Micrococcus luteus and Bacillus megaterium.
What are the official names of this protein?
Proenkephalin-A.
What is the protein family that this protein belongs to?
Belongs to the opioid neuropeptide precursor family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen. Secreted.
Protein: NHAA_PHOPR
Sequence: MTDAIRKFLKLESAGGIILIIAAAVAMVIANSPLQSLYSGTLSSYIAGLSVEHWINDGLMAIFFMLIGLEVKRELIEGALNTKEKAIFPAIAAVGGMVAPALVYVAFNFADPIALQGWAIPAATDIAFALGVMALLGNRVPVSLKVFLLALAIIDDLGVIVIIALFYSSDLSTLALAVAFAATATLFVMNAKNVTKTSLYLIVGAILWFSVLKSGVHATLAGVVLGFAIPLTGKDGRSDKHSPLKHLEHVLHPYVAFLILPLFAFANAGISLDGVSLESVTGMLPLGIAAGLFLGKPLGIFTASYIAVKMGLATLPDGINLKHIFAVSVLCGIGFTMSIFISSLAFVGAPADFNTYSRLGILMGSTVAAVVGYILLSRTLPKTEA
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GMSS_CARHZ
Sequence: MKEVNLVLGVIGADVHAIGNKILEYALTNAGFKVHNLGVMVSQEEFVKAALETDAKAVLVSSLYGHGEIDCRGLKEKFIEAGLDDVLLYVGGNLVVGKQDFSEVERKFKAMGFDRVFPPGTMPEEAIKALKEDLGLM
What is the function of this protein?
Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
What are the official names of this protein?
Glutamate mutase sigma subunit, Glutamate mutase S chain, Glutamate mutase small subunit, Methylaspartate mutase.
What is the protein family that this protein belongs to?
Belongs to the methylaspartate mutase GlmS subunit family.
Protein: PQQB_CUPNH
Sequence: MTSIRVLGSAAGGGFPQWNCNCHNCDGVRRGTVRATPRTQSSIALTGDGPDAILVNASPDILQQLRQAPALQPARAPRDTAIAAVVLMDAQIDHVTGLLMLREHREALPLYATAAVLDDLGAAFPLTRILSHYCGLRTHALPCDGTAFSVPPLDGLTLTAIPLESKAPPYSPNRHAPRAGDNIGLRIEDRRSGRSAFYAPGLGRIDDHVFAELHSADIVLVDGTFWRDDEMQAPGFSGKSAADMGHLALSGPGGMIEVLERLPASRKILIHINNTNPVLVEDSPERAELARHGIEVAYDGMEIAL
What is the function of this protein?
May be involved in the transport of PQQ or its precursor to the periplasm.
What are the official names of this protein?
Coenzyme PQQ synthesis protein B, Pyrroloquinoline quinone biosynthesis protein B.
What is the protein family that this protein belongs to?
Belongs to the PqqB family.
Protein: SECA_TREDE
Sequence: MLDSIIKILFGSKHERDIKAMLPILHKINEKEAWALSLSEEEFKAKTDEFRERYQKGESLDSFIPEAFALAREAARRILGERPYDVQILGSLVLHSGKIVEMKTGEGKTLMSVAAAYLNSLTGKGVHIVTVNDYLAERDADWMRPVYSYLGVSVGVILSNMENDARRIEYNCDITYGTNNEFGFDYLRDNMQMRLKDKTQREFSFAIVDEIDSILIDEARTPLIISGAAEDDTQRFFEVDRLIGQLKEVEKNPETGEYPNELEGEEVIGDYTIDEKSKRVSFTDSGMLHIQDILQRQGLIKSGNLFDEENFEYIHYFTQSVRAHVLFHIDVDYVIQDGQVQIVDEFTGRVLEGRRYSDGLHQAIEAKEHIKIAQRNRTLATITFQNFFRMYDKLSGMTGTADTEAVEFTKIYNLDVVVIPTNLPVARKDEHDVIYLNENDKFEALCTEISEAYKRGQPVLVGTVSIEKSELISKLLTKRGVRHEVLNAKNHEREALIIAEAGAKGSVTIATNMAGRGTDIKLGGSPEMRAKKRTGTNPNPDYYEKVLAEEYAKWQSDYNEVKELGGLYVIGTERHESRRIDNQLRGRSGRQGDPGRSKFFLSLDDDLMRLFGGENLKNVMSKIGMRAGEPIEHPWINKSIEKAQTKVENRNFDIRKHLLEYDDVLNEQRSFIYEQRNAILEDENLIERIYATLEEFISEKFDEYSSSSKAEKEERARLIKDIFREKFSYTLTEEDFANIDKKNHEEEINEFVEHFTKELKEKEALAGKENLNMFIRYQYLQAIDKKWLDHLENLESLREAVYLRSYGQKNPLTEYKLEGFDIFYSMLDDIRIEIASRLVRVQISTEEEAHASRQMRSIQGNAQHNSMGSFSGSGHGMGPTALSARSRPENAQVVRTVPKVGRNDPCPCGSGKKYKYCCGKNG
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: MOAC_PAENI
Sequence: MRLESWSPGLTHLRTDGTAHMVDVSEKVESTREATLREQFVQLSEVLLLLTSDGLPKGDALAVARISGILATKKTSELIPLCHPLPVSQATVDFVLGSDRVQTLCKAVKTRGVTGVEMEALTAVSVAALNLYDMFKAIDKHAVLTDIRVLAKSGGKSGDWDLGTSEEKA
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: RS7_STAAB
Sequence: MPRKGSVPKRDVLPDPIHNSKLVTKLINKIMLDGKRGTAQRILYSAFNLVEQRSGRDALEVFEEAINNIMPVLEVKARRVGGSNYQVPVEVRPERRTTLGLRWLVNYARLRGEKTMEDRLANEILDAANNTGGAVKKREDTHKMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RL333_LACLM
Sequence: MLRKAGLACTVCGSRNYTLNLSSVAKEKRVEVKKFCRTCGKHTLHKETR
What are the official names of this protein?
50S ribosomal protein L33 3.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: MBL1_MOUSE
Sequence: MLLLPLLPVLLCVVSVSSSGSQTCEDTLKTCSVIACGRDGRDGPKGEKGEPGQGLRGLQGPPGKLGPPGSVGSPGSPGPKGQKGDHGDNRAIEEKLANMEAEIRILKSKLQLTNKLHAFSMGKKSGKKLFVTNHEKMPFSKVKSLCTELQGTVAIPRNAEENKAIQEVATGIAFLGITDEATEGQFMYVTGGRLTYSNWKKDEPNNHGSGEDCVIILDNGLWNDISCQASFKAVCEFPA
What is the function of this protein?
Calcium-dependent lectin.  Plays a role in the innate immune response by binding mannose, fucose and N-acetylglucosamine moieties on different microorganisms and mediating activation of the lectin complement pathway (By similarity).  Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages (By similarity).
What are the official names of this protein?
Mannose-binding protein A, MBP-A, Mannan-binding protein, Ra-reactive factor polysaccharide-binding component p28B, RaRF p28B.
What are the subcellular locations of this protein?
Secreted.
Protein: SYH_MANSM
Sequence: MAKTIQAIRGMNDCLPTETPVWQWVESKVRSTLASYGYSEIRMPIVENTPLFARAIGEVTDVVSKEMFTFNDRDNESLTLRPEGTAGCVRAGIEHGLLYNQEQRLWYMGPMFRYERPQKGRYRQFHQAGVEVFGIANAEIDAELIILTARLWKELGIEQHVTLQLNSIGSLEARANYRSALVEFLQQYVGLMNEEEKERLLKNPLRILDTKNEALQQALNNAPKLLDYLDDDSREHFARLCAILDNVGISYEINPKLVRGLDYYNKTVFEWVTTALGAQGTICGGGRYDGLVEQLGGHATCGVGFAMGLERLILLVQEVNKAIPLPQSAVDIYLIFAGENTASAAFRLAEKVRSELPHLRTMMHCSGGNFKKQFKRADKSGAKIALVLGESEVQNQQVVVKDLLGGAEQQTVALEAVIDHLKTSFKE
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYI_RHILO
Sequence: MTDTVETIDYSKTLYLPQTDFPMRAGLPEKEPVLVKRWQDMDLYAKLRESAAGRTKYVLHDGPPYANGNIHIGHALNKILKDVITRSFQMRGYDSTYVPGWDCHGLPIEWKIEEQYRAKGKNKDEVPVNEFRKECREFAAHWITVQGGEFQRLGVIGDFKNPYTTMAFHAESRIAGELLKFALSGQLYRGSKPVMWSVVERTALAEAEIEYQDYESDTIWAKFPVANLVVANVVDGQPAELNPDLSDRSLDLLDAHVVIWTTTPWTIPGNRAVSYSPRVAYGLYEVTAAENAFGPEPGEKLIFADALAAESQAKAKITLKRLHHVSAEQLGNLVLSHPFKGLGGGYEFPVPMVAGDHVTDDAGTGFVHTAPGHGREDFDAWMDAAPQLRARGIDTVIPFTVDDAGFFTRDAPGFGPDREGGAARVIDDNGKKGNANQAVIDELIKRNALFARGRLKHSYPHSWRSKKPVIFRNTPQWFVYMDKDLGDGTTLRSRALKAIDDTRFVPAAGQNRIRAMIEERPDWVLSRQRAWGVPIAVFADEDGNVLKDEAVNQRIMDAFEEEGADAWFAAGAKERFLGNHDASKWKQVMDILDVWFDSGSTHVFTLEDRPDLKWPADVYLEGSDQHRGWFHSSLLESCGTRGRAPYDTVVTHGFTMDEDGRKMSKSLGNTVVPQDVIKQSGADILRLWVVTTDYWEDQRLGKNVLQTNIDAYRKLRNTIRWMLGTLAHDDGETVPLEAMPELERLMLHRLAELDEVVRQGYDAFEFKRITRALVDFMVVELSAFYFDIRKDALYCDAPSSVKRKASVQVVRHLFDCLVKWLAPMLPFTMEEAWLDRHPDAVSVHLDQFPEIPADWKNEALAEKWRKVRQVRRVVTGALEIARAQKVIGSSLEAVPVVTINDAALEAAIADVDMAEMAITSDLVIAHGQAPEGAFTLDDVRGVAVVVEKAEDRGLVKCARSWRYTADVGQDPAFPDVSARDAAVLHELKALGRL
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIFH2_CLOPA
Sequence: MRQLAIYGKGGIAKSTTTQNLTAGLVERGNKIMVVGCDPKADSTRLLLGGLAQKTVLDTLREEGEDVELDSILKTGYAGIRCVESGGPEPGVGCAGRGIITSINMLEQLGAYTDDLDFVFYDVLGDVVCGGFAMPIREGKAQEIYIVASGEMMALYAANNISKGIQKYAKSGGVRLGGIICNSRKVANEYELLDAFAKELGSQLIHFVPRSPSVTKAEINKKTVIEYDPTCEQANEYRELARKVEENDMFVIPKPMTQERLEQILMEHGLID
What is the function of this protein?
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
What are the official names of this protein?
Nitrogenase iron protein 2, Nitrogenase Fe protein 2, Nitrogenase component II, Nitrogenase reductase.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.