PharMolix/UniProtQA huggingface dataset:
Protein: PREP_SCHPO
Sequence: MNYAKLSIAFSKKTIKTHNCRLFQRWLHVGDKVHDFRVVDTKKVPELQLNYTRLKHEPTNADMIHLDREDPNSVFSIGFQTPAENDEGIPHILEHTTLCGSNKYPVRDPFFKMLNRSLATFMNAFTASDFTFYPFATVNTTDYKNLRDVYLDATLFPKLRKLDFLQEGWRFEHADVNDKKSPIIFNGVVYNEMKGQVSDSSYIFYMLFQQHLFQGTAYGFNSGGDPLAIPDLKYEELVKFHRSHYHPSNAKILSYGSFPLEDNLSALSETFRPFSKRELNLPNTFLKEFDQEKRVVEYGPLDPVMAPGRQVKTSISFLANDTSNVYETFALKVLSKLCFDGFSSPFYKALIESGLGTDFAPNSGYDSTTKRGIFSVGLEGASEESLAKIENLVYSIFNDLALKGFENEKLEAILHQMEISLKHKSAHFGIGLAQSLPFNWFNGADPADWLSFNKQIEWLKQKNSDGKLFQKLIKKYILENKSRFVFTMLPSSTFPQRLQEAEAKKLQERTSKLTDEDIAEIEKTSVKLLEAQSTPADTSCLPTLSVSDIPETIDETKLKFLDIAGMKAQWYDLAAGLTYIRLLLPLKNFPESLIPYLPVYCDACLNLGTHSESIGDLEHQIRRYTGGISISPSAVTNNSDVSKYELGIAISGYALDKNVGKLVELINKAFWNTNLSNTDKLAIMLKTSVSGITDGIAEKGHSFAKVSSASGLTEKTSITEQLGGLTQVKLLSQLSREESFGPLVEKLTAIREILRGTSGFKAAINASPTQHEVVEKALQKFMKSRGVNQQTQTKSTSKERNGINSIKTYHELPFQTYFAAKSCLGVPYTHPDGAPLQILSSLLTHKYLHGEIREKGGAYGAGLSYSGIDGVLSFFTYRDSDP
What is the function of this protein?
Degrades mitochondrial transit peptides after their cleavage in the intermembrane space or in the matrix, and presequence peptides; clearance of these peptides is required to keep the presequence processing machinery running (By similarity).  Preferentially cleaves the N-terminal side of paired basic amino acid residues (By similarity).  Also degrades other unstructured peptides (By similarity).  May function as an ATP-dependent peptidase as opposed to a metalloendopeptidase (By similarity).
What are the official names of this protein?
Presequence protease, mitochondrial, PreP, Pitrilysin metalloproteinase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M16 family. PreP subfamily.
Protein: HAT1_HUMAN
Sequence: MAGFGAMEKFLVEYKSAVEKKLAEYKCNTNTAIELKLVRFPEDLENDIRTFFPEYTHQLFGDDETAFGYKGLKILLYYIAGSLSTMFRVEYASKVDENFDCVEADDVEGKIRQIIPPGFCTNTNDFLSLLEKEVDFKPFGTLLHTYSVLSPTGGENFTFQIYKADMTCRGFREYHERLQTFLMWFIETASFIDVDDERWHYFLVFEKYNKDGATLFATVGYMTVYNYYVYPDKTRPRVSQMLILTPFQGQGHGAQLLETVHRYYTEFPTVLDITAEDPSKSYVKLRDFVLVKLCQDLPCFSREKLMQGFNEDMVIEAQQKFKINKQHARRVYEILRLLVTDMSDAEQYRSYRLDIKRRLISPYKKKQRDLAKMRKCLRPEELTNQMNQIEISMQHEQLEESFQELVEDYRRVIERLAQE
What is the function of this protein?
(Microbial infection) Contributes to hepatitis B virus (HBV) replication by acetylating histone H4 at the sites of 'Lys-5' and 'Lys-12' on the covalently closed circular DNA (cccDNA) minichromosome leading to its accumulation within the host cell.
What are the official names of this protein?
Histone acetyltransferase type B catalytic subunit, Histone acetyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the HAT1 family.
What are the subcellular locations of this protein?
[Isoform A]: Nucleus matrix. Mitochondrion. SUBCELLULAR LOCATION: [Isoform B]: Cytoplasm. Nucleus. Nucleus matrix. Nucleus, nucleoplasm. Note=Localization is predominantly nuclear in normal cells. Treatment with hydrogen peroxide or ionizing radiation enhances nuclear localization through redistribution of existing protein.
Protein: ERA_ENTFA
Sequence: MTTEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNKIQGIYTIPEAQIVFIDTPGIHKPKHRLGDFMVESAYNAMREVDATLFMVSADQKRGKGDDFIIERLKNNNSPVYLIINKIDKVHPDDLLSIIEDYSKQMDFKEIIPISATEGNNFEHLMDVLVEQMPEGPQYFPDDQITDHPEYFIVSELIREKVLLLTRDEIPHSVAVVVDSMKRDENDKVHVQATIIVERDSQKGIIIGKGGKMLKQIGTKARQDIEYLLDDKVYLELWVKVQKDWRDKKIYLQDFGYRKEEY
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: STIP1_MOUSE
Sequence: MEQVNELKEKGNKALSAGNIDDALQCYSEAIKLDPQNHVLYSNRSAAYAKKGDYQKAYEDGCKTVDLKPDWGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEANNLQLKEGLQNMEARLAERKFMNPFNLPNLYQKLENDPRTRSLLSDPTYRELIEQLQNKPSDLGTKLQDPRVMTTLSVLLGVDLGSMDEEEEAATPPPPPPPKKEPKPEPMEEDLPENKKQALKEKELGNDAYKKKDFDKALKHYDRAKELDPTNMTYITNQAAVHFEKGDYNKCRELCEKAIEVGRENREDYRQIAKAYARIGNSYFKEEKYKDAIHFYNKSLAEHRTPDVLKKCQQAEKILKEQERLAYINPDLALEEKNKGNECFQKGDYPQAMKHYTEAIKRNPRDAKLYSNRAACYTKLLEFQLALKDCEECIQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDLDSSCKEAADGYQRCMMAQYNRHDSPEDVKRRAMADPEVQQIMSDPAMRLILEQMQKDPQALSEHLKNPVIAQKIQKLMDVGLIAIR
What is the function of this protein?
Acts as a co-chaperone for HSP90AA1.  Mediates the association of the molecular chaperones HSPA8/HSC70 and HSP90.
What are the official names of this protein?
Stress-induced-phosphoprotein 1, STI1, mSTI1, Hsc70/Hsp90-organizing protein, Hop.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Dynein axonemal particle.
Protein: ASTB_IDILO
Sequence: MQHFEVNYDGLVGPTHNYAGLSFGNVASLANAKATSSPKHAALQGLKKMKALHDMGMKQGVLAPQERPDIFALRRLGFHGTDSEVLYRAATEAPAIFQAVCSASSMWTANAATVSPSADTANGKVHFTPANLTNKFHRSLEPQTSGRILQAMFNNGRYFEHHTHLPDNEHFGDEGAANHTRLCREYGHAGIELFVFGRYAFDSSKPAPKRFPARQTLEASQAIARLHGLSEDNTVYIQQNPDVIDQGVFHNDVIAVGNQNVLFYHEQAFTDTESKLAEIQRKFGEHPLHFIKVATEQVSIQDAVNTYLFNTQLITPPDGQMTIIAPTECQENDNVRSYLEQLTQSADSPIKRVEYFDVKQSMRNGGGPACLRLRVALNDEEIAGANQNCLMSDGLFNRLNQWVEKHYRDELAVDDLRDPALLEESRTALDELTQIMKLGSVYPFQQD
What is the function of this protein?
Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
What are the official names of this protein?
N-succinylarginine dihydrolase.
What is the protein family that this protein belongs to?
Belongs to the succinylarginine dihydrolase family.
Protein: LHB1_RHOAC
Sequence: AEVLTSEQAEELHKHVIDGTRVFLVIAAIAHFLAFTLTPWLH
What is the function of this protein?
Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
What are the official names of this protein?
Light-harvesting protein B-800/820 beta chain, Antenna pigment protein beta chain, LH3 complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the antenna complex beta subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: COQ5_CHICK
Sequence: MAAGLCPGRALLSRRGGALWALLGTARGRAAGPETHFGFQNVSEAERREKIYQVFENVAEKYDVMNDSMSLGIHRVWKDILVHKMNPSPGTLLVDVAGGTGDIAFRFLNYVRSVRERQLQQKLRHHQNLSWQEISKSYQEEKSNPLGDSQVVVCDINKEMLKAGKQKAQHLGYSEGLSWVLGNAEELHFDDDKFDVYTIAFGIRNVTRIDLALQEAYRVLKPGGRFLCLEFSHVSNPLLSRLYDLYSFQVIPVLGEVIAGDWKSYQYLVESIRRFPPQEELKAMIEDAGFLKVDYQNLNSGIVAIHSGFKL
What is the function of this protein?
Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial, Ubiquinone biosynthesis methyltransferase COQ5.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: RL3_FRATM
Sequence: MSLGLVGRKCGMTRIFTEDGVSIPVTVVQVEPNKVTQVKTVEKDGYNAIQVTTGFKKRSNVNKPMAGHYAKASVEPGRGLWEFTVDAAAEYQVGSSFDATMFEAGQKVDVRGVSKGKGFQGGVKRHNFATQDATHGNSLSHRVHGSTGQNQTPGRVFKNKKMAGHLGNENVTIQSLEVVRVDAENGLLLLKGGIPGSVGGDIIVTPAVKS
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: SFGH1_SHISS
Sequence: MELIEKHASFGGWQNVYRHYSQSLKCEMNVGVYLPPKAANEKLPVLYWLSGLTCNEQNFITKSGMQRYAAEHNIIVVAPDTSPRGSHVADADRYDLGQGAGFYLNATQAPWNEHYKMYDYIRNELPDLVMQHFPATTRKSISGHSMGGLGALVLALRNPDEYVSVSAFSPIVSPSQVPWGQQAFAAYLGENKDAWLDYDPVSLISQGQRVAEIMVDQGLSDDFYAEQLRTPNLEKICQEMNIKTLIRYHEGYDHSYYFVSSFIGEHIAYHANKLNMR
What is the function of this protein?
Serine hydrolase involved in the detoxification of formaldehyde.  Hydrolyzes S-formylglutathione to glutathione and formate (By similarity).
What are the official names of this protein?
S-formylglutathione hydrolase FrmB, FGH.
What is the protein family that this protein belongs to?
Belongs to the esterase D family.
Protein: YCIB_RALPJ
Sequence: MKFLFDLFPVILFFAAFKVAGIYVATTVAMVATVLQIAWVWFKHRKVDAMQWLSLLIIGVFGGATLIFHNETFIKWKPTVLYWLFGVVLLGSVVVVRKNLIRAMMEQQVSLPETMWGRLNLVWALFFLVMGCLNLYVAYNFDTDVWVNFKLFGSMGLMVVFILAQSVWLARHMQERPANAANDANIGDDR
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MSRA2_STAAR
Sequence: MTKEYATLAGGCFWCMVKPFTSYPGIKSVVSGYSGGHADNPTYEQVCTNQTGHVEAVQITFDPEVTSFENILDIYFKTFDPTDDQGQFFDRGESYQPVIFYHDKHQKKAAEFKKQQLNEQGIFKKPVITPIKPYKNFYPAEDYHQDYYKKNPVHYYQYQRGSGRKAFIESHWGNQNA
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA 2, Protein-methionine-S-oxide reductase 2, Peptide-methionine (S)-S-oxide reductase 2, Peptide Met(O) reductase 2.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: RM44_BOVIN
Sequence: MASGLTRLLLRGPRCLLATAGLTLIPPVRGVKKGFRAAFRFQKELERWRLLRCPPPPVRRSEKPNWDYHAEIQAFGPRLQETFSLDLLKTAFVNSCYIKSEEAKRQKLGIEKEAVLLNLKDNQELSEQGTSFSQTCLTQFFEDAFPDLPTEGVKSLVDYLTGEEVVCHVARNLAVEQLTLSADFPVPPAVLRQTFFAVIGALLHSSGPERTSLFIRDFLITQMTGKELFEIWKIINPMGLLVQELKKRNISVPESRLTRQSGSTTALPVYFVGLYCDKKLIAEGPGETVLVAEEEAARVALRKLYGFTENRQPWDYSRPKEPVRAEKTIAAS
What is the function of this protein?
Component of the 39S subunit of mitochondrial ribosome.  May have a function in the assembly/stability of nascent mitochondrial polypeptides exiting the ribosome.
What are the official names of this protein?
39S ribosomal protein L44, mitochondrial, L44mt, MRP-L44.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family. Mitochondrion-specific ribosomal protein mL44 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ZSC21_HUMAN
Sequence: MMTKVLGMAPVLGPRPPQEQVGPLMVKVEEKEEKGKYLPSLEMFRQRFRQFGYHDTPGPREALSQLRVLCCEWLRPEIHTKEQILELLVLEQFLTILPQELQAWVQEHCPESAEEAVTLLEDLERELDEPGHQVSTPPNEQKPVWEKISSSGTAKESPSSMQPQPLETSHKYESWGPLYIQESGEEQEFAQDPRKVRDCRLSTQHEESADEQKGSEAEGLKGDIISVIIANKPEASLERQCVNLENEKGTKPPLQEAGSKKGRESVPTKPTPGERRYICAECGKAFSNSSNLTKHRRTHTGEKPYVCTKCGKAFSHSSNLTLHYRTHLVDRPYDCKCGKAFGQSSDLLKHQRMHTEEAPYQCKDCGKAFSGKGSLIRHYRIHTGEKPYQCNECGKSFSQHAGLSSHQRLHTGEKPYKCKECGKAFNHSSNFNKHHRIHTGEKPYWCHHCGKTFCSKSNLSKHQRVHTGEGEAP
What is the function of this protein?
Strong transcriptional activator (By similarity).  Plays an important role in spermatogenesis; essential for the progression of meiotic prophase I in spermatocytes (By similarity).
What are the official names of this protein?
Zinc finger and SCAN domain-containing protein 21, Renal carcinoma antigen NY-REN-21, Zinc finger protein 38 homolog, Zfp-38.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRUD_LEGPL
Sequence: MYSLNWPRAYGIPNSTATFKLCPEDFQVNELFEGQFSGEGEHIVLKIEKKGLTTEQVIKSLARLINKPIKLISYAGLKDKQALTTQWLSIHAPGEVIEGIETLEAPGWKILECTRHNKKLRPGFLSGNHFTITLRNVSDESDLIHRIEQIKFKGVPNYFGEQRFGRDGGNLIKAEEILVQGRKVKDRFLKGMYFSAARSWLYNLILSRRVKESSWNLPLLGDVIQLVGSNSIFVNDKSLDEQLLQRIGEKDVSPASPLPGRSKNLVKGTALQIINEVYAEWSAWLDGLEKNGLEEAWRANILYAEQIEYRINQGTVELSFVLPAGAYATVVLRELVQY
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: PDXH_KINRD
Sequence: MEDPAGRRVDYGDRRFDEHDLAPTPLAQFQAWYSDAVEAGVVEPNAMTVATAGADGVSARTVLLKAVDGRGFVFYTNQRSRKALAIAHDPRVALLFTWHGTHRQVAVRGTAEEVPRAETEAYFASRPYGSRIGAWVSEQSRTTPSAAALHEREAQLRERWPDTGSPDDVPTPPHWGGYLVRALEVEFWQGRTSRLHDRLVLVAADGPARLDDPAPWRTERRQP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: QUEA_STRT2
Sequence: MNTNDFDFELPEELIAQTPLEQRDASKLLVIDPVTREMTDTHFDHIIDQLNPGDALVMNNTRVLPARLYGEKTDTHGHVEFLLLKNTQGDQWEVLAKPAKRLKVGAKVSFGDGRLTATVTEELDHGGRIVEFSYNGIFLEVLESLGEMPLPPYIHEKLEDRDRYQTVYAKENGSAAAPTAGLHFTPELLQKIEAKGVKLVYLTLHVGLGTFRPVSVDNVDEHEMHSEFYTLSQEAADTLNSVKAAGGRIVAVGTTSIRTLETIGNKYDGQLQADSGWTNIFIKPGYQFTVVDAFSTNFHLPKSTLVMLVSAFAGREFVLEAYKHAIQERYRFFSFGDAMFVTRPSEK
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXA_PSYA2
Sequence: MSQIHPTALISPSATIDETATIGPYCIVGDEVTIGAHTVLHRHVVVTRLTRIGEHNQFYQFSSIGEDPQDLKYAGERTWLEIGDHNTIREACSLHRGTEQDGGLTKIGSHNLLMVNTHVAHDCLIGDHNVLANNVGVAGHVTIGNHIIVGGNSGIHQFCTIDDYSLVGGATLVLKDVAAFTMVSGNPAKAHGLNVEGMRRKGWSKDSIDVLRQAYRVVFRSGLTTVQALEVLKQDLLPKEQKIEFLIDSLQKSRRGVVR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMA_ECO27
Sequence: MPWIQLKLNTTGANAEDLSDALMEAGAVSITFQDTHDTPVFEPLPGETRLWGDTDVIGLFDAETDMNDVVAILENHPLLGAGFAHKIEQLEDKDWEREWMDNFHPMRFGERLWICPSWRDVPDENAVNVMLDPGLAFGTGTHPTTSLCLQWLDSLDLTGKTVIDFGCGSGILAIAALKLGAAKAIGIDIDPQAIQASRDNAERNGVSDRLELYLPKDQPEEMKADVVVANILAGPLRELAPLISVLPVSGGLLGLSGILASQAESVCEAYADSFALDPVVEKEEWCRITGRKN
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T2B_PARTE
Sequence: MKTIILALALIALVSSTQSDVIDTIKKIDQSPFGRTLFDTIWLELQTGDPLDRLVSTLTDLEDRYVAEQKEDDAKNQEYQGACTVDITAFDKDLAESNRKKIELEARLEGQLYPQRSILEGLVAQKKAEVKGYQKDLDELDAQRAEEHEDFEEKVLEHQEATAIIAEARRLFADNIEHESFVQKGKAAKQPHKFTKDVANLIQKHFTTSAKKTAKFQHRKGYSKLFKAFATIASKVEQLADAGAVQKIIDLADELLAKISDSLSLLRFAEDKRVESYKKSRNFVVIALNVAGSALANAISDLAALNDIIAQVEASLDTTVQRIENVSADRHDRFTQCEEAVQDYSDARSARQSDRDVVSQTIGLVNKELRTLREQLALRQQAGEQI
What is the function of this protein?
Structural protein that crystallize inside the trichocyst matrix.
What are the official names of this protein?
Trichocyst matrix protein T2-B, Secretory granule protein T2-B, TMP 2-B.
What is the protein family that this protein belongs to?
Belongs to the TMP family.
What are the subcellular locations of this protein?
Trichocyst. Note=These are architecturally complex secretory storage granules-docked at the plasma membrane, ready to rapidly respond to an exocytotic stimulus.
Protein: MED14_PICST
Sequence: MDEIHGEVSPPAINRSNGALVSDNISQVVEGVDNVERPAKVAKGYSAANRPPPELPHITNNVIPLSNVLKFYTQEAFKQITTLVENLASTKDSEDDSVRKKKFLELIIALRQDFIKIYTLVKWAANSKDVSRFIDLLNWLRMQEFYFDQLTFQLNALNGYSGAKLPNSDLITSLEVLFKGRPQLPSYNYIKIPKISPEKTLEVMQDLNLILMTRIALIDIPKRFINNYVIKDGRIYFSVPNEFQVSITVANDMIIESHDEYTKSPFYFIDFKFLFGINPDTSLITHRDNKIVTKLPRSSHENLEKIVNATLLNQGLHGLYDLLHKFSISFKLYLIAKQLKELQINTRWRNNLQVNYQNGKSLIILNYWSGQYLSKGWKSFIELGIDRNYNLNFRWFKNGKYNVNTELSALFNKHLKNTNEGEEEKDDSTDDIEEPEDLNVDLILNIVVNKHSELLMSKVFNSLDAKLNTTDNPDQISYITPHQLLIKSSPTKSTIFCINPLTGLFYFIDPCPVQNLIAKKINSPPTVVKNKNFVAESDMVNTIVDGLTQLRLEIFNKEIHNRLLTTEWINNDIIGLNDYEISRLSNFFANSLDYNLNVNKIQFYRRKNWPSSWFLINLVSGVTSVTFWWVARIKSVSGEWKIQWIQKLHLNEKTPSVEITDDPTNLNFEFFNNLSTACSNMIIDHMLLEELFKRNIKFLKVDNTALILQKFNIDKIPDDEDTQDTDDKNKPLIYESIIMIYNDNNLLPVYNSATSLFLKIKLINLNNLTQMKLKLFGKLRNLSIRNSPENFLQLNLKIDEIKNFFEIDDLINLSSRTNGSDSASSATTNHLLDKIFNNLNKLNKLIKILDQLNKNKIQIINNSVNDIIIKIDDNLDNLIIKLPEKATDSIKLISEEEVKDGGNPEVKLILDYLNKYLSNYYSDDFFANDEDKFYDGNKKTSIVGIIKYLKEINPILKSVQTIKAKLRKPESAFKLSNGLSKLNFDIKFTTLNLIQYVFHMNYQTPSSSKKIFKDKIVISLSFKNNKFDKVSKNLIKISLKDNLNSKNLKYKKLFELIFKSINDGSMDAHAHQLIKLNYDFLVNSSLVGELMVRIANCFVLYLQAESNGRYNQ
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 14, Mediator complex subunit 14.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 14 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL22_BACFN
Sequence: MGARKKISAEKRKEALKTMYFAKLQNVPTSPRKMRLVADMIRGMEVNRALGVLKFSSKEAAARVEKLLRSAIANWEQKNERKAESGELFVTKIFVDGGATLKRMRPAPQGRGYRIRKRSNHVTLFVGSKSNNEDQN
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: KRR1_DICDI
Sequence: MGKKDKTEIKVEEENKEKKQYKKKKEREELEIPKGIDPWKPLELKRDDVGKRVLYDDSSFATLFPKYREKYLQEIWKLVENVLHEHGIECKLDLIEGSMTVTTTKKCWDPVAILKARDLIKLLSRSVPFEHAQKVLNDDYNCDIIKIGGFVRNKERFVKRRQRLVGPDGSTLKAIELLTKCYVLVQGNTVSSIGPWNGLVQVRKIVEDCLKNIHPIYNIKELMIKRELEKDETLKNENWERYLPQFKKTNQNKKKKVQKKKKDRDAAPFAPPQLPRKEDLAMESGEYFASEEKKRRKIQADREAKHAESDQKRKDERQKSQIAPAEKDRSTTTTTNTSNIQDTLSNIKNNLKNNKRKEAPTNNADDFVLKKNKK
What is the function of this protein?
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
KRR1 small subunit processome component homolog, KRR-R motif-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the KRR1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: YCF4_PELHO
Sequence: MSCRSENLWLELIAGSRKTSNFLWALILFLGSFAFLLVGTSSYLGRNWISLFPSQQILFFPQGVVMSFYGIAGLFISSYLWCTISWNVGSGYDRFDRKEGIVCIFRWGFPGRNRRIFLRFLMKDIQSIRIEAREGFYARRILYMEIRGQGAIPLTRTAENWTPREIEQKAAELAYFLRVPMEVF
What is the function of this protein?
Seems to be required for the assembly of the photosystem I complex.
What are the official names of this protein?
Photosystem I assembly protein Ycf4.
What is the protein family that this protein belongs to?
Belongs to the Ycf4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RF3_LIGS1
Sequence: MDKKQLEESVNNRRTFAIISHPDAGKTTITEQLLLFGGVVRKAGTVKAKKSGNFAKSDWMEIEKKRGISVTSSVMQFDYAGKRVNILDTPGHEDFSEDTYRTLMAVDSAVMVIDSAKGIEPQTKKLFQVCRMRGIPIFTFINKLDRDGREPLDLTAELEDVLGIESYAMNWPIGMGKGLKGLYDIYNHRIELYRSEDEGQAFLELDDNGEIKGDNPLKDESIYKQVLEEIELIEGAGSEFDEEKIAKGELTPVFFGSALTNFGVKTFLDAYLKYAPKPAAHKTEDGSEVEPDRKDFSGFIFKIQANMNPNHRDRIAFVRICSGEFDRGMDVFLERTGKKLRLSNSTQFMADTRETLETAVAGDIIGLYDTGNFQIGDSIYTGKKAVKFEKLPQFTPELFMRVTAKNVMKQKSFHKGIQQLVQEGAVQLYQSYSTGDYILGAVGQLQFEVFQFRMANEYNSEVVMTPMGHKIARWIDPEQLDEKMSSSRNLLVKDRAGMPLFLFENEFAERWFMDKYPDVKLTAKL
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPRT_ASFP4
Sequence: MSILEKITSSPSECAEHLTNKDSCLSKKIQKELTSFLQKKETLGCDSESCVITHPAVKAYAQQKGLDLSKELETRFKAPGPRNNTGLLTNFNIDETLQRWAIKYTKFFNCPFSMMDFERVHYKFNQVDMVKVYKGEELQYVEGKVVKRPCNTFGCVLNTDFSTGTGKHWVAIFVDMRGDCWSIEYFNSAGNAPPGPVIRWMERVKQQLLKIHHTVKTLAVTNIRHQRSQTECGPYSLFYIRARLDNVSYAHFISARITDEDMYKFRTHLFRIA
What is the function of this protein?
Cysteine protease that plays several role during infection including processing of the structural polyprotein or inhibition of the host immune response.  Catalyzes the maturation of the pp220 and pp62 polyprotein precursors into core-shell proteins.  Plays a role in the disruption of host pyroptosis via specific cleavage of gasdermin D/GSDMD.  In addition, strongly decreases the host cGAS-STING signaling by targeting IKBKE via its enzymatic activity.  Impairs also host FOXJ1-mediated antiviral effect via degradation of FOXJ1.
What are the official names of this protein?
SUMO-1 cysteine protease S273R, pS273R.
What is the protein family that this protein belongs to?
Belongs to the peptidase C63 family.
What are the subcellular locations of this protein?
Host cytoplasm. Virion. Note=Found in cytoplasmic viral factories during assembly.
Protein: YCF4_NOSP7
Sequence: MTTSTTINKGDRLLHQNVLGSRRFSNYWWATIVTLGASGFLLAGISSYLKVNLLIVSDPTQLVFVPQGLVMGLYGAAGLLLATYLWLVILLDVGGGYNEFNQETGTIKIFRWGFPGKNRRIEIDSRIEDVQSVRIAVKEGLNPIRALYLRIKGRRDIPLTRVGQPLSLTELETEGAKLARFLGVSLEGL
What is the function of this protein?
Seems to be required for the assembly of the photosystem I complex.
What are the official names of this protein?
Photosystem I assembly protein Ycf4.
What is the protein family that this protein belongs to?
Belongs to the Ycf4 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.