PharMolix/UniProtQA huggingface dataset:
Protein: PRP18_PONAB
Sequence: MDILKSEILRKRQLVEDRNLLVENKKYFKRSELAKKEEEAYFERCGYRIQPKEEDQKPLTSSNPVLELELAEEKLPMTLSRQEVIRRLRERGEPIRLFGETDYDAFQRLRKIEILTPEVNKGLRNDLKAALDKIDQQYLNEIVGGQEPGEEDTQNDLKVHEENTTIEELEALGESLGKGDDHKDMDIITKFLKFLLGVWAKELNAREDYVKRSVQGKLNSATQKQTESYLRPLFRKLRKRNLPADIKESITDIIKFMLQREYVKANDAYLQMAIGNAPWPIGVTMVGIHARTGREKIFSKHVAHVLNDETQRKYIQGLKRLMTICQKHFPTDPSKCVEYNAL
What is the function of this protein?
Participates in the second step of pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-splicing factor 18, PRP18 homolog.
What is the protein family that this protein belongs to?
Belongs to the PRP18 family.
What are the subcellular locations of this protein?
Nucleus speckle. Note=Colocalizes with spliceosomal snRNPs.
Protein: Y1441_METJA
Sequence: MKITFYMWASYCSILKKALDELKKEGVDVEYKIYSNRNPIDDEFLEDAKDYDLVFIYRTSSDDIDLEKIKKFNENVIVVAQDPNFWNSEKSAKCYLFITYGGLDNFKNMVLYLMGKDKDVVKHPFQGIYYRGKIYEELEEFLKDVEFNKKYTVGILFSRHYLVNDDMDVIEKLLNRLDKEFNVIPVFSYGAKCEDLNALGSGESVLKYFLKDDKPIIDALINLLSFPLGTVKDKANLNKISGVEILKKLDVPVFHPIMSYYKSYEDWKKDEQGLSADIGWTIALPEFEGVIEPIIIGTTENENGLEKKFGIEERIDKVVRRIKRWIELKYKPKKDRKVIFILHNNACASVEATVGSAAHLDSFQSVINIMKKLKEEGYYVENIPENGEELAQLIMQKKAISEFRWTTVNEIIAKGGYLYLMDEEEYYEYFNTLPENVKNKILETWGDLNGKDIPAGMIYKVNGKNKIVITGLKFGNVYVCVQPKRGCAGARCDGRVCKILHDPYCPPTHQYIASYKYFNDIADIIIHVGTHGTLEFLPGKNVGLSNECYPDICIGDIPHLYIYNSDNPPEGTIAKRRSYATIIDHMQTVMVDAFYEELETLDSYIEEYLKEMDASRRHQLEHLIVEEVKKTNLLKIKEKIEKIEKEGKIHENFKEIFDELRDILEMIKNSKCNDGMHIFGELPSGEKRVEFIKSILEAIFIQNNTMNSKRRGIAERSEAMHPGYPNRGLPPMEFEYKDKNLKKKVSDVLNGKSIEDKKLEEKIKDINERIEKSDEIGSLLRGIDAKYIEPGPSGLITRGNYDILPTGRNFYSLDPYRIPTKSAYRVGVLLAEKLINRYLEEEGRYPENIALYWMASDIMWADGEGMGMILYLLGVKPVYRGGRVVGLEVIPLEELGRPRIDVTIRVSGITRDMFPNCIELVDEAIMKVANLDEPLEMNFVKKHVVENLNKGLSFRESTFRIFCSPPGTYGNGVKYAVYASAWENDEDLKDAFIYWNSYAYGKDVYGKKAINAFENILKTVDLTFNKVVTDEYDLFGCCCYFGTHGGLTNAARVLKGEEVKAYYGDTRNPNNVEVRTLKEEIERVSLTKLLNPKWIEGMKRHGYKGAGDIAKRIGRVYGWSATTKEVENWIFDEIFNTFVKNEENRKFFKEHNIYALEEIARRLLEAYQRGLWKTTEGNIEELKRAYLEIEGDIEETYSSIADIGEFQGGSVDIDMIWKEKLMSNGR
What are the official names of this protein?
Uncharacterized protein MJ1441.
What is the protein family that this protein belongs to?
Belongs to the Mg-chelatase subunit H family.
Protein: TALB_ECOL6
Sequence: MTDKLTSLRQYTTVVADTGDIAAMKLYQPQDATTNPSLILNAAQIPEYRKLIDDAVAWAKQQSNDRAQQIVDATDKLAVNIGLEILKLVPGRISTEVDARLSYDTEASIAKAKRLIKLYNDAGISNDRILIKLASTWQGIRAAEQLEKEGINCNLTLLFSFAQARACAEAGVFLISPFVGRILDWYKANTDKKEYAPAEDPGVVSVSEIYQYYKEHGYETVVMGASFRNIGEILELAGCDRLTIAPALLKELAESEGAIERKLSYTGEVKARPARITESEFLWQHNQDPMAVDKLAEGIRKFAVDQEKLEKMIGDLL
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase B.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_YERPA
Sequence: MARKTPIERYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAATTCFWSGMAKQFEPHHVNIIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQPQSETVWRQANKYKVPRIAFVNKMDRMGANFLRVVGQLKSRLGANPVPLQLAIGAEEKFTGIIDLVKMKAINWNEADQGVTFEYEEIPADMAELAAEWHQNLVESAAEASDELMDKYLGGEELTEEEIKKALRQRVLKSEIILVTCGSAFKNKGVQAMLDAVIEYLPAPTDVESINGILDDGKDTPAVRHSDDKEPFSALAFKIATDPFVGNLTFFRVYSGIVNSGDTVLNSVKSQRERLGRIVQMHANKREEIKEVHAGDIAAAIGLKDVTTGDTLCDPNNPIILERMEFPEPVISVAVEPKTKADQEKMGMALGRLAKEDPSFRVWTDEESGQTIIAGMGELHLDILVDRMRREFNVEANVGKPQVAYRETIRETVKDVEGKHAKQSGGRGQYGHVVIDMSPLPPGGVGYEFVNEIVGGSIPKEFIPAVDKGIQEQLKSGPLAGYPVVDVKVRLHYGSYHDVDSSELAFKLAGSIAFKEGFKRAKPVLLEPIMKVEVETPEDYMGDVMGDLNRRRGIIEGMEDTATGKTVRVKVPLSEMFGYATDLRSQTQGRASYSMEFLEYAEAPSNVAKAVIEARGK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTNG1_MOUSE
Sequence: MYLSRFLSIHALWVTVSSVMQPYLFVWGHYDVCKSLIYTEEGKVWDYTACQPESTDMTKYLKVKLDPPDITCGDPPESFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLHAFHMDPKSVKDLSQHTVLEIICTEEYSTGYSTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCNLHATSCLYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPGNSWYYGCQPNVCDNELLHCQNGGTCQNNVRCACPDAYTGILCEKLRCEEAGSCGSESGQGAPPRGSPALLLLTMLLGTAGPLVF
What is the function of this protein?
Involved in controlling patterning and neuronal circuit formation at the laminar, cellular, subcellular and synaptic levels.  Promotes neurite outgrowth of both axons and dendrites.
What are the official names of this protein?
Netrin-G1, Laminet-1.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side.
Protein: CNSJ_PENEN
Sequence: MTVDTAPQSHYQETKVSEIPIVILKSSATDDVAAHEAIEALKVAGVCIVRNLLDRSTVDKVRQELQPYDKQADSFEGFPKNYCQVAGLLSKSPTYAHSIVGNKLFTAVRNYFLTSTYECWAEKGTWMSVKSPPQLDSTLALYVNPGSGDQGLHRDDATQQNWNSGASEYSLGRDSGCAMMVALTECAREDGTTRFIPGSHLWDYQYDHPSNDDPRIRYAEMRPGDAYLMLSSVIHAGSVNYSTDRRRVLAAVFAARSHLRQVENQYLTYDIETVRTFPTWLQRFMGYSLSKLFQGWVDKKDPLLVVDPNAQPEGEDDGGMKPNEGEHVVEAQI
What is the function of this protein?
Dioxygenase; part of the gene cluster that mediates the biosynthesis of communesins, a prominent class of indole alkaloids with great potential as pharmaceuticals (PubMed:25571861).  Communesins are biosynthesized by the coupling of tryptamine and aurantioclavine, two building blocks derived from L-tryptophan (PubMed:25571861).  The L-tryptophan decarboxylase cnsB converts L-tryptophan to tryptamine, whereas the tryptophan dimethylallyltransferase cnsF converts L-tryptophan to 4-dimethylallyl tryptophan which is further transformed to aurantioclavine by the aurantioclavine synthase cnsA, probably aided by the catalase cnsD (PubMed:25571861).  The cytochrome P450 monooxygenase cnsC catalyzes the heterodimeric coupling between the two different indole moieties, tryptamine and aurantioclavine, to construct vicinal quaternary stereocenters and yield the heptacyclic communesin scaffold (PubMed:26963294).  The O-methyltransferase cnsE then methylates the communesin scaffold to produce communesin K, the simplest characterized communesin that contains the heptacyclic core (PubMed:25571861).  The dioxygenase cnsJ converts communesin K into communesin I (PubMed:25571861).  Acylation to introduce the hexadienyl group at position N16 of communesin I by the acyltransferase cnsK leads to the production of communesin B.  The hexadienyl group is produced by the highly reducing polyketide synthase cnsI, before being hydrolytically removed from cnsI by the serine hydrolase cnsH, converted into hexadienyl-CoA by the CoA ligase cnsG, and then transferred to communesin I by cnsK (PubMed:25571861).  Surprisingly, cnsK may also be a promiscuous acyltransferase that can tolerate a range of acyl groups, including acetyl-, propionyl-, and butyryl-CoA, which lead to communesins A, G and H respectively (PubMed:25571861).  The roles of the alpha-ketoglutarate-dependent dioxygenases cnsM and cnsP have still to be determined (PubMed:25571861).
What are the official names of this protein?
Dioxygenase cnsJ, Communesin biosynthesis cluster protein J.
What is the protein family that this protein belongs to?
Belongs to the PhyH family.
Protein: RLMD_SHESM
Sequence: MAQFFKAKPNSSKQLSAKQSFSVHQLDHLGAGIAQHQGKVVFIPGALPSETVQAQLTEQKKNYARAKLIKVETPSAERVTPLCPHYQSCGGCDLQHMSLAGQREHKSAALVDIMAKFAGAEGNSVPALTGEGWHYRRRARLATLFDKNTKQLSLGFRASSSNQVVPIDSCLVLAKPLSDLIAPFAKLLNQLAAKSSLGHLELIDADNGHFAVIRITKSLNDKDMAKLAQFAEHHQIHICLQDNNGEFHGVNGTLLLPVYQLLDDKAGATPVSLTFTPGNFVQVNAQINKAMVAQALDWLAPQPGERILDLFCGMGNFSLPLAKLGAEVIGVEGVPDMVSQARENAAANGLSNLTFYHGDLSADLSCEPWMGKIDKLLLDPARAGAFESLQWLKKMKPRQVVYVSCNPASLARDSAVLLERGYKLQKLGLIDMFPQTHHIEAMALFELAK
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: SYP_SALHS
Sequence: MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLPTGLRVLKKVENIVREEMNNAGAIEVSMPVVQPADLWQESGRWEQYGPELLRFVDRGERPFVLGPTHEEVITDLVRNELSSYKQLPLNFFQIQTKFRDEVRPRFGVMRSREFLMKDAYSFHTSQESLQETYDAMYAAYSRIFSRMGLDFRAVQADTGSIGGNASHEFQVLAQSGEDDIVFSDVSDYAANIELAEAIAPQTPRAAATQEMTLVDTPNAKTIAELVEQFNLPIEKTVKTLLVKAVKDSKSPLVALLVRGDHELNEVKAEKLPHVASPLTFATEEEIRAVINAGPGSLGPVNMPIPVIIDRTVAAMSDFAAGANIDGKHYFGINWDRDVATPVVADIRNVVAGDPSPDGQGTLLIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTRVVAAAIEQNFDERGIVWPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVLMDDRKERPGVMFADMELIGIPHTIVIGDRNLDNDDIEYKYRRSGEKSLIKTGDIVDYLVKAIKG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CUTC_MOUSE
Sequence: MKKGASCERKQAWISSGKAGAGNGFLMEVCVDSVESAVNAERGGAGRIELCSGLLEGGTTPSMGVLQVVKQSVQIPVFVMIRPRGGDFLYSDREVEVMKADIRLAKLYGADGLVFGALTEDGHIDKELCLSLVALCRPLPVTFHRAFDMVHDPMAALETLLTLGFERVLTSGCDSSALEGLPLIKQLIDQAKGRIVVMPGGGITDKNLQRILEGSGATEFHCSARSSRDSGMKFRNSSVAMGASLAHSEYSLKVTDVTKVRTLNAIAKDVLV
What is the function of this protein?
May play a role in copper homeostasis.  Can bind one Cu(1+) per subunit (By similarity).
What are the official names of this protein?
Copper homeostasis protein cutC homolog.
What is the protein family that this protein belongs to?
Belongs to the CutC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: LIVB7_BRUA2
Sequence: MEKHLIALSVAALQAGAAPASADIKMGSLYPFSGPLALLGDESARGLEIAVEEINAKGGVQGEKIVLVRGDAVDNNQAIGEARRLISVENVAGIFGSFSSGRAVAASQVSELAGVPYFELGAVADEITDRGLENVYRANPYARDFAQMIVEMLQKKIAPKLGRDSKDLKIAVIYEDSSYGTSVAKHEETFLKEAGLNMVLSQSYPGNTVDMSSLVLDLKSAGADVVLQTSYQSDSVLFLQQANEGGYKPSAIVGAGGGYSLQPTADAVGHDVIEAAYDVDFTQFAVNTSFTPGLEEFVEAYKKKYGETPRSGYSLTNYVGAKVILEALNKVKGFDAAAVKQALSAVDIEAGKTAMGYGFKFDQNNQNERASMMGMQWQDGKLVTVYPDAAAISEIRLPQ
What is the function of this protein?
Component of an amino-acid transport system.
What are the official names of this protein?
Leu/Ile/Val-binding protein homolog 7.
What is the protein family that this protein belongs to?
Belongs to the leucine-binding protein family.
Protein: MCMD2_RAT
Sequence: MGKLPMKEAALVYLDRSGGLQKFMDDCKYYNDSKQSYAVYRFSILINPCDVVELDAELGNHILHHPLKAAQVFQSVCFVAVKTLSLIGKLQTETQINIVLKLTHLPSLPSYSLDLCEFPLNYASQRFYMMQGIVIAMTTVTKYTQGARFLCSDEVCPFSKGFQYIRVHVPGATESATVRNDFLCRLCSSSLQEDRKFRVLGDKQIIEIITTKVLHAFQGDPKNQPFRFQSLSVFLRDELVNKMKIGNEYKIIGIPVCVKTSQTALCVEANSITPYTAKVPSGISDNFRCLLSLTSSSCWRFTAILANVFASHIVPLGTYNLLKLCLLMSLVQTRDCSSERENCLDILVITSDTLLVDRLLNFSMNLVSRGIRHPVCTEVFPTVSRDKYGTGAVSIQAGSALLARGGVCFIGDLTSHKKDKLEQLQSALESRSVTVFIPGKKFGDDFDQQMTFPIQCSFWSFVDMDSSSRRNVQKASTLIGQMDCSLIPANLAEAFGLLVNCKESSPCHPLLPTVQHTLKKAVDPKGPPYLASKQFTTEDFEKLLAFAKNLNVEFSLEAERMIHGYYLASRRIRTDSIHGSKLSANALKYLVSLSEAHARLNLRNKVLREDVLIAALLFEISLTLKYGATAFCVAPNALFPFELYDEDYLEQRDLYLTQCQQQLQHFIATCGPGTAVLSSDE
What is the function of this protein?
Plays an important role in meiotic recombination and associated DNA double-strand break repair.
What are the official names of this protein?
Minichromosome maintenance domain-containing protein 2, MCM domain-containing protein 2.
Protein: SYH_VIBPA
Sequence: MAKTIQAIRGMNDCLPTQSPLWQKLENTVKNVISAYGYNEVRMPIVEETNLFSRAVGEETDVVSKEMYTFDDRNGDSLTLRPEGTAGCVRSCIQNSLINRDEQRLWYMGPMFRHERPQKGRYRQFHQCGVEVFGLNGPDVDAELIMMTARLWRELGIDKHVRLELNSIGSQEDRADYRTALVAFLEQHIDVLDEDCKRRMHTNPLRVLDTKNPDIQAILGDAPRLSEYLGEESKAHFAGLCELLDAAGIEYTVNERLVRGLDYYNRTVFEWITESLGAQGTVCGGGRYDGLVEQLGGKPTPAVGFAMGLERLVLMLETLELTDVRRSVDVYVVTAGEGTMMAGMKLAEQLREAISGVRVMNHFGGGNFKKQFKRADKVGAVVALVLGENEVADNTVVLKDLVGGEQETYNQAEVAEKIAALI
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOK_NOCFA
Sequence: MNPANYLFLSALLFTIGAAGVLLRRNAIVVFMCIELMLNAVNLAFVTFARMHANLDGQVFAFFTMVVAAAEVVVGLAIIMTIFRARRSTSVDDANLLKF
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYC_AROAE
Sequence: MLHIHNTLTRRKEAFVPIAPGKVRMYVCGMTVYDYCHLGHARVMVVFDMVARWLRASGFELTYVRNITDIDDKIIRRAGEKGESIRTLTDRFIAAMHEDADALGVLRPDHEPRATEYVMQMQSLIGRLRDKGLAYVAGNRDVCYSVRKFDSYGRFSGKSLDELRAGERVEVAGDKQDPLDFVLWKHARTDEPDEVKWASPWGAGRPGWHIECSAMSSDLLGEQFDIHGGGQDLQFPHHENEIAQSEGAHGHTFVNYWMHNGFVRVDDEKMSKSLGNFFTIRDVLERFDPEVVRFFILRAHYRSPLNYSDAHLEDARQALTRLYTALRNVQPSDAQVDWDEPHAMRFRAAMDDDFNTAEAVAVLFELANEANRSGSAATAAQLKGLGGVLGLLAREPASFLQGRMAGEPDKGEGVAIESMIERRALAKKSKDYAEADRIRAQLLASGIVLEDTPHGTVWRRA
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LAMB_SHIF8
Sequence: MMITLRKLPLAVAVAAGVMSAQAMAVDFHGYARSGIGWTGSGGEQQCFQTTGAQSKYRLGNECETYAELKLGQEVWKEGDKSFYFDTNVAYSVAQQNDWEATDPAFREANVQGKNLIEWLPGSTIWAGKRFYQRHDVHMIDFYYWDISGPGAGLENIDVGFGKLSLAATRSSEAGGSSSFASNNIYDYTNETANDVFDVRLAQMEINPGGTLELGVDYGRANLRDNYRLVDGASKDGWLFTAEHTQSVLKGFNKFVVQYATDSMTSQGKGLSQGSGVAFDNEKFAYNINNNGHMLRILDHGAISMGDNWDMMYVGMYQDINWDNDNGTKWWTVGIRPMYKWTPIMSTVMEIGYDNVESQRTGDKNNQYKITLAQQWQAGDSIWSRPAIRVFATYAKWDEKWGYDYNGDSKVNPNYGKAVPADFNGGSFGRGDSDEWTFGAQMEIWW
What is the function of this protein?
Involved in the transport of maltose and maltodextrins.
What are the official names of this protein?
Maltoporin, Maltose-inducible porin.
What is the protein family that this protein belongs to?
Belongs to the porin LamB (TC 1.B.3) family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: YIDD_FERNB
Sequence: MRKVILKLIRFYQKYISPLKPPTCRFEPTCSTYTYQAVERFGILKGLLLGFWRVLRCNPISKGGHDPVPTEFYLFKKSNNSLRRR
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ACYP_METCA
Sequence: MKRVHVLVAGRVQGVWYRASAARKASELGLTGWVRNLPDGRVELVAEGDAESVDALLAWCRRGPPLARVTGLDVREMAVTGEFTEFAVLRDV
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: PCDBI_MOUSE
Sequence: MAARGSCVSRQRQVLFLFLLGGLCLAGSELGRYSVTEETERGSFVANLAKDLGLGVEALAAKRTRVVCDDNKQHLFLDSHTGDLLTNEKLDREKLCGPTEPCMLYFQILMDNPFQIYRAELRILDINDHSPIFQDKKMILKILENTAVGTTFRLERAQDSDGGRNGIQNYTISPNTFFHITVHNSDEGMIYPELVLDKALDWEGQPEFSLTLTALDGGSPPRSGTATIHILVLDINDNAPQFPQELYEIQAPENSPIGLVVIKVTGEDVDSGVNAEISYSFFDASEDIRATFQINPFSGEITLKALLDYEFIKSYKLNVQAVDGGGLSARCTVLVRVLDVNDNAPELIMSSLVNEVVENSPETVLAVFRINDRDSGENGKMVCHIQENLPFLLKPSVDNFYILMTEGALDRESRAEYNITITVSDLGTPRLTTQHTIRVQVSDINDNAPAFNQTSYTLFVRENNSPAMHIGTISATDSDAGSNAHITYSLLPTQDLQMTLTSLVSINADNGQLFAIKALDYEALQAFEFHVGATDRGSPELSSQALVRVVVLDDNDNAPFVLYPMQNASAPYTELLPRTAEPGYLVTKVVAVDRDSGQNAWLSFQLLKATEPGLFSVWAHNGEVRTTRLLSERDVPKHRLLLLVKDNGDPPRSASVTLQVLLVDGFSQPYLPLPEVAHNPTQGEEDVLTLYLVIALASVSSLFLLSVLLFVGVRLCRRARAASLGGCSVPEGHFPGHLVDVSGTGTLSQNYQYEVCLMGGSSGTSDFKFLKSIYPEVHAYSSQDNSDGNPTF
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.
What are the official names of this protein?
Protocadherin beta-18, PCDH-beta-18.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PGMC_MESCR
Sequence: MATFKVSRVETKPYDGQKPGTSGLRKKVKVFAQPHYLENFVQSTFDALTADKIKGKTLVVSGDGRYYSEQAIQTIIKMSAANGVKSVWVGQDGLLSTPAVSAVIRERVGKDGSKASGAFILTASHNPGGPNEDFGIKYNMENGGPAQEGVTNKIYENTTTIKEYLIAKELPNVNISKTGVTSFSGPDGQFDVEVFDATETYVKLMKSIFDFQAIKKLLSIPSFTFCYDALHGVAGVYAKRIFVDELGANESSLLNCTPKEDFGGGHPDPNLTYAKELVERMGLGKSNTQGEPPEFGAAADGDADRNMILGKRFFVTPSDSVAIIAANAVEAIPYFSGGLKGVARSMPTSAALDVVAKHLNLKFFEVPTGWKFFGNLMDAGVCSICGEESFGTGSDHVREKDGIWAVLAWLSILAHKNKDNLNGEKLVTVEDIVCQHWATYGRHYYTRYDYENVDAGGAKELMAYLVNLQSDLSKVNNIVKGVHSGVANVIAADEFEYKDPVDGSVSKHQGIRYMFEDGSRLIFRLSGTGSEGATIRLYIEQYEKDSSKTGRDSQEALKPLVDVALKLSKMQEFSGRSEPTVIT
What is the function of this protein?
This enzyme participates in both the breakdown and synthesis of glucose.
What are the official names of this protein?
Phosphoglucomutase, cytoplasmic, PGM, Glucose phosphomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG9_KLUMD
Sequence: MVDNQDNVNEPPKNTFLSRVFGVHSSAVENSIDGAEMSHISIHNSQEFNHFVENEHHERLIESDQESSTNEEESNDEEPLIKQPQSIRFQEVPNGIAITHPFSESEDDEGEIEGRDPEFFSDQDLGSSISKHGQGSSSEDESEQAPTGDDAGPIGFERNSPIVENTRLGFHSPYDANSKANLKGPYLGHSKVFDRIFANKPAGMSRNRRHDDLEESFLFRKPSVADPRSTKTPAPFNLKPPPIFQNVPNLTSVNKNSLSTLSPKERALWKWANVENLDTFLQQVYDYFLGNGFYCIIVDKVVQLATILFVVFISTYMGHCIDYSRLSSSHSFKEVHIEQCYKTQISPTAKVLLWIFYAFIGLKILQLYFDVKALKDVQNFYNYLLGISDKDLPTIPWQSVVQQLVLLKDQNAITANATEVKAKNRLSAHDVANRIMRKENFVIALYDNNILDLSLPIPLFRTCALTKSLEWNINLCILGFAFNERGYLKQAFLRESQREYLSEELKKRFVLAGFLNIILSPFLVTYFILLNFFRYFNEYKTTPGSIGSRQYTPIAEWRFREYNELYHIFEKRKKLSMVIADDYISQFPNTLMSSLLSFVQFVSGSFVAILGILTVFDPDNFLNFEITSDRTVLFYMTLFGSIWAICHGAINEEYTAFSPEETLRELISFTHYSPKSWEGKYHTEDIKEEFCKLYNLRIILLLKELVSIILTPFILWFSLPKNSDRIIDFFRECTVYEEGLGYVCKYAMFDGAKVNKGLNAKTQASKMFSQTDNDDESDSDNDIGVNKMLQSYMYFVDDYKKAENALGKNQLISPKEGSFGYPRDYSWKTQFALGKKINKRSGEGPSQRRNLEHGSANPDVGSLNASFINKSSLYKDDFTENTDEMKKGNGVMGLLNQYYKKYDNKR
What is the function of this protein?
Phospholipid scramblase involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation.  Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome.  Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.  Required for mitophagy.  Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress.  Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.
What are the official names of this protein?
Autophagy-related protein 9.
What is the protein family that this protein belongs to?
Belongs to the ATG9 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RIBX_MIMIV
Sequence: METDKYVFFHGANKNQAGVHIFSQWFPVNFKEYLNGEEFAEYVSAEQYMMAHKALLFGDMFHFKKIMECSKQCKIKYLGRRVRNFNPTIWDKHKFDIVTEGNRLKFSQNPDLMKRLLETGNKTIVEASPSDKIWGIGLTAQQAVNIPENKWPGKNLLGKVLMKIREENQQ
What is the function of this protein?
Catalyzes the hydrolysis of the N-glycosidic bond in the first two intermediates of riboflavin biosynthesis, which are highly reactive metabolites, yielding relatively innocuous products.  Thus, can divert a surplus of harmful intermediates into relatively harmless products and pre-empt the damage these intermediates would otherwise do.  May act on other substrates in vivo.
What are the official names of this protein?
N-glycosidase R617, Riboflavin biosynthesis intermediates N-glycosidase.
What is the protein family that this protein belongs to?
Belongs to the YbiA family.
Protein: DXR_MYCTU
Sequence: MTNSTDGRADGRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAAQRVGDIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEHVTPEQAGAHPTWSMGPMNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASPPDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGFPAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGMASVAIASTAKPGAAGRHASTLERS
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: ATPB_LEGPH
Sequence: MSLGTVVEVIGAVVDVEFPRDSVPKVNDALKLVDSDLVFEVQQQLGDGVVRTIAMGTTDGLKRGLKAENTGHPIQVPVGKKTLGRIMDVLGRPVDDAGPIDAEETWAIHRKAPSYEEQAGSQELLETGIKVIDLLCPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMKDSNVLDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFIDNIYRYTLAGVEVSALLGRMPSAVGYQPTLAEEMGMLQERITSTKTGSITSIQAVYVPADDLTDPSPATTFAHLDATVVLSRQIAELGIYPAVDPLDSTSRQLDPLIVGQEHYDTARRVQQTLQRYKELKDIIAILGMDELSEEDKRVVTRARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIKGFQGILAGEYDDLPEQAFYMVGSIEEAVAKAKTL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.