PharMolix/UniProtQA huggingface dataset:
Protein: ENO_AROAE
Sequence: MSAIVDIIAREILDSRGNPTVEADVLLESGVMGRAAVPSGASTGSREAIELRDGDAARYLGKGVLQAVENVNTEISETLIGLDAEEQAFIDRTLIELDGTENKSRLGANATLAVSMAIAKAAAEEAGLPLYRYFGGSGPMAMPVPMMNVINGGAHANNSLDIQECMIMPVSMTSFREALRCGAEIFHHLKKLTDKKGYPTTVGDEGGFAPNVGGTEEALNMIQDAIAAAGYEPGRDVLLALDCAASEFYKDGQYVLAGEGLTLSSEGFADYLATLADRFPIVSIEDGMAENDWAGWKTLTDKLGRRLQLVGDDLFVTNTRILEQGIDQGVANSILIKINQIGTLSETFAAVEMAKRAGYTAVISHRSGETEDSTIADIAVGLNAMQIKTGSLSRSDRISKYNQLLRIEEDLGDTVSYPGRRAFYNLRVR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: ARNE_SALEP
Sequence: MIGVILVLASLLSVGGQLCQKQATRPLTVGGRRRHLMLWLGLALICMGAAMVLWLLVLQTLPVGIAYPMLSLNFVWVTLAAWKIWHEQVPPRHWFGVALIISGIIILGSAA
What is the function of this protein?
Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
What are the official names of this protein?
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE, L-Ara4N-phosphoundecaprenol flippase subunit ArnE, Undecaprenyl phosphate-aminoarabinose flippase subunit ArnE.
What is the protein family that this protein belongs to?
Belongs to the ArnE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MLE_DICDI
Sequence: MSASADQIQECFSIFDKDNDGKVSVEDIGACLRSLGKSPTMADIEALKTEIGAKEFDINTLKSIYKKPNIKTPQEQQKEMLDAFKALDKEGHGTIQGAELRQLLTTLGDYLSTAEVDELFKEISVDSTTGAVSYASLVNTIVSGYPLGGF
What are the official names of this protein?
Myosin, essential light chain, EMLC, Myosin light chain alkali.
Protein: SOML_GADMO
Sequence: MHTLAAVVVLQVCWAAVLWPCPPTHSSPVDCREEQAGSSQCPTISQEKLLDRVIQHTELIYRVSEESCSMFEDMFVPFPVRLQRNQAGNTCITKDFPIPTSKNELQQISDTWLLHSVLMLVQSWIEPLVYLQTTLDRYDDVPDVLLNKTKWMSEKLISLEQGVVVLIRKMLDGAILNSSYNEYSAVQLDVQPEVLESILRDYNVLCCFKKDAHKIETILKLLKCRQIDKYNCALY
What are the official names of this protein?
Somatolactin, SL.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRPCD_ARCFU
Sequence: MMDFGFVDSLKGASKRGKNAVIAEVKVRSPIHGDLLRGRRIEDILRAYEKAGAAAISYITAEQFSGNFETLKKIVGLTDLPVLRKDFIRGRKEVERTAEVEAAALLLIARHLKERTAEMVDFCFEHGIEPLVEVHHAEDLVYAENARAVLINNRDIDRMERDGGSIDVTAKIAEKIRAFKVSGSGIGSVEDLLFVLQYVDAALIGTAFMMAENTEEFVQTVCGGEKMIEDVLRGLDFDKAYELAKTLPELDEIKIAAVLAALEAKGYGAEVIAGFAKGVAEKSKIEIGKVMDTCGTGGDKTSSINVSTAVAIALSTVHPVAKHGNRAVSSKSGSADVLEALGVRIEMDEERARKMIAETNFAFLFAPLYHKSFARVAAVRRNLGIRTIFNVTGPLTNPARPEVQIVGVASEILLVEVAKAMSLLGRRAVVVYGSGMDEVNPNSSTDIAVVNGGVERLKLEPEDFGIERCRVLPCSSSGESAERIRAVFSGKGLKEDRRLIAINFATALFALGYEDLKENVEIFEEKVQSGELARKLEEIACKSTSM
What is the function of this protein?
Bifunctional enzyme that catalyzes the second and fourth steps of tryptophan biosynthetic pathway.  The second step is catalyzed by the anthranilate phosphoribosyltransferase, coded by the TrpD domain and the fourth step is catalyzed by indole-3-glycerol phosphate synthase, coded by the TrpC domain (By similarity).
What are the official names of this protein?
Tryptophan biosynthesis protein TrpCD.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the anthranilate phosphoribosyltransferase family.
Protein: TRPC_SULDN
Sequence: MILDEIIKKTREDIIKRESEFSLDWLGRSLAFNSRAPRDVFSYLSATPEDPYRVIAEVKKASPSRGVIRENFDPIAIAQSYEIGGASAISILTEPHFFQGNLDYLAQIRRYVSIPLLRKDFIVTKYQILEALVHGADFILLIAAALSKAELKELLGYTRHLGMEALVEVHDKSDLVKAIYAGSDIIGINHRNLQTFEMNMNLSYELIPLIPNGKIIVAESGIYEHGQLEDLSKAGVDAFLVGESLMREDDEEAALKKLKFGSN
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: HOA_POLNA
Sequence: MNLQGKQVTVHDMTLRDGMHPKRHLMTLDQMKSIACGLDAAGVPLIEVTHGDGLGGSSVNYGFPAHTDEEYLGAVIPLMKQAKVSALLIPGIGTVEHLLMAKDLGVGTIRVATHCTEADVSEQHITKSRALGLDTVGFLMMAHMASPEKLVSQALLMQGYGANCIYVTDSAGYMLPDDVKARLGAVRAALKPETELGFHGHHNMAMGVANSIAAIEAGANRIDAAAAGLGAGAGNTPMEVFIAVCARMGIETGVDVFKIQDVAEDLVVPIMDHIIRIDRDSLTLGYAGVYSSFLLFAKRASVKYGVPARDILVELGRRGMVGGQEDMIEDTAMTMARERGLTLAAA
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase, HOA, 4-hydroxy-2-keto-pentanoic acid aldolase, 4-hydroxy-2-oxopentanoate aldolase.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: VATC_CAEEL
Sequence: MSSATSGEYWLISVPGEKGANDAWDKLNRSTGNTSTNSKYLIPDLKVGTLDQLVGLSDDLSKLDTSAEAVIRKLVQYFTEVLEEDKSKIAENLVIGNKDMKTYVTKFQWEGAKYPLKQSLKVLSEIIGKQISQIDNDLKVKSLTYNNLKNALASMDRKTVGSLLTKDLADLVKADDFVLNSEYLQTVIVVVPKISVKEWEQKYATLSSMVVPGSSKLLTEEGEHALYTVTLFKKVIDEFKNTARENKFIVRDFVYDEETLKAGRTERDKLMAEKQRQYAPLIRWLKINFGEIFAAYIHIKALRVFVESVLRYGLPVNFQAAVIEPAKGQQKKLRQELHKLYIHLDGSAAGPIDTLEDSPALMSLGVNEYYPYVFFKLNIDFLNK
What is the function of this protein?
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (Probable).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).  Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity (By similarity).  Has roles in embryogenesis and ovulation (PubMed:10846178).
What are the official names of this protein?
V-type proton ATPase subunit C, V-ATPase subunit C, Vacuolar proton pump subunit C.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase C subunit family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein. Note=In embryonic cells, detected in dot-like structures in the cytoplasm around the nuclei.
Protein: RS7_METSB
Sequence: MSRRHSAEKREVIPDAKFGDVILTKFMNSIMYDGKKSVAEAIVYDAFDIIEQKARTEPLGVFKQALENVAPAIEVRSRRVGGATYQVPVEVRMERRQALAIRWIITAARGRNDKTMVDRLSAELMDAANNRGNAVKKREDTHRMAEANRAFSHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: COAA_BRUA4
Sequence: MWEKVDQLTPSRYSPYRFFSAEEWAGFRADTPLTLTYDEVKRLRSLGDPIDLDEVRRIYLSLSRLLSAHVEASQLLFEQRKQFLNMEESFKTPFIIGIAGSVAVGKSTTARILKELLARWPSSPKVDLVTTDGFLYPNAVLREQNMMERKGFPESYDVGAVLRFLSAIKAGMSQVRAPLYSHLSYDVLPGEYQIVDKPDILIFEGINVLQVRDLPEDGKMVPFVSDFFDFSIYIDAESQLIHKWYIDRFMRLRETAFVNPESFFHRYSQLSEDAARSIGEGLWNNINLKNLKDNILPTRPRADLILRKGSDHLIEEVALRKI
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCNA2_CHICK
Sequence: MLAEQENQENVPPAAKAPPPAAGTRVALGLLRGGPARPGPAAQAARNGEGRGAAAGQQQQPFSVYVDEPDEERRRPQRKKERDEEAADAPGLRAALGTVGERRPLAPLGNAMELSLDSPSIMDISITSEAEERPNVNNVPDYVSDIHTYLREMEVKCKPKIGYMKKQPDITNNMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYNKKQVLRMEHLILKVLSFDLAAPTINQFLTQYFLHQQTNAKVESLSMYLGELTLIDADPYLKYLPSVIAAAAFHLASYTITGQTWPESLCKVTGYTLEHIKPCLMDLHRTYLKAAQHTQQSIREKYKSTKYHAVSLIDAPETLDL
What is the function of this protein?
Cyclin which controls both the G1/S and the G2/M transition phases of the cell cycle.  Functions through the formation of specific serine/threonine kinase holoenzyme complexes with the cyclin-dependent protein kinases CDK1 and CDK2.  The cyclin subunit confers the substrate specificity of these complexes and differentially interacts with and activates CDK1 and CDK2 throughout the cell cycle.
What are the official names of this protein?
Cyclin-A2, Cyclin-A.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: Y1624_METJA
Sequence: MRRDEYFEKLLEVIEELKIEAEEKPIIVEGKRDVESLEKLGVEGTFIIIAKTPIYLIADELVRKRVKEVILLTDFDRRGRMLAKAIIEEFRHRGIKVNTKIRHEIFIYTNSGIRDIESLFSYVNKRLF
What are the official names of this protein?
UPF0292 protein MJ1624.
What is the protein family that this protein belongs to?
Belongs to the UPF0292 family.
Protein: OBG_KLEP3
Sequence: MKFVDEATILVVAGDGGNGCVSFRREKYIPKGGPDGGDGGDGGDVWLEADENLNTLIDYRFEKSFRAERGQNGQSRDCTGKRGKDVTVKVPVGTRVIDQGTGETMGDMTKHGQRLMVAKGGWHGLGNTRFKSSVNRTPRQKTMGTPGDKRDLQLELMLLADVGMLGMPNAGKSTFIRAVSAAKPKVADYPFTTLVPSLGVVRMDNEKSFVVADIPGLIEGAAEGAGLGIRFLKHLERCRVLLHLIDIEPIDGSDPVENARIIVGELEKYSEKLASKPRWLVFNKIDLMDKAEAEAKAKAIAEALGWEDKFYLISAASQQGVKELCWDVMTFIIENPIVHVEEEQKPEKVEFMWDDYHRQQLEEAEVEVEDDEDWDDDWDEDDEEGVEFIYKR
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRXC_PSEFL
Sequence: MTTFTTRDGTQIYYKDWGSGQPIVFSHGWPLNADSWESQMIFLAAQGYRVIAHDRRGHGRSSQPWSGNDMDTYADDLAQLIEHLDLRDAVLFGFSTGGGEVARYIGRHGTARVAKAGLISAVPPLMLKTEANPGGLPMEVFDGIRQASLADRSQLYKDLASGPFFGFNQPGAKSSAGMVDWFWLQGMAAGHKNAYDCIKAFSETDFTEDLKKIDVPTLVVHGDADQVVPIEASGIASAALVKGSTLKIYSGAPHGLTDTHKDQLNADLLAFIKG
What are the official names of this protein?
Non-heme chloroperoxidase, Chloride peroxidase, Chloroperoxidase F, CPO-F.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Bacterial non-heme haloperoxidase / perhydrolase family.
Protein: FEN1_PLAKH
Sequence: MGIKGLTKFIADAAPNAIKEIKIENLMGRVVAIDASMSLYQFIIAIRDSEQYGNLTNESGETTSHISGLMSRSIKLMENGLKPIYVFDGAPPELKGSELEKRGEKRQKAEELLKKAKEEGNLEEIKKQSGRTVRVTKKQNEEAKKLLTLMGIPVVEAPCEAESQCAFLTKYNLAHATATEDADALVFGTKILIRNLNANASSTSQNKNKNSSKRGYILTEINLEQVLKGLNLNMNEFIDFCILCGCDYCDTIKGIGSKTAYNLIKEYNSIEKIIENIDKNKYQIPSNFRFVEARDSFINPKVLSKEEIKIDWGEPKIEELKNFLIKDYNFNEVRVTNYINRLLKARKVTTQRRLDNFFTACTKKSTKLVNEESQIKKEVKPKRKGKKRDAPNDSSTKLNSKQNKKPKGEKESKTEKDDGDTHNGNDNEEEGGEGETADMGAKDPFDTEEDEDNPSVNFFHHKSDSESGNVKKESTEQEANATPTGDVYSFPNGKDASGSNIHLSSNSTLHSCNNLNGDKAINESMHVVGSSAPEAGNNEIGNGDLFTSNAADCVNNNTDKTQAEIEMKKKNISFLLPYCPKNVTSVKKRKSVQRC
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: MURC_SULSY
Sequence: MFRGKVRKIHFIGIGGSGMNGIAELLLNQGYTITGSDLKESPTIERLRNLGAKIFIGHSEENVKDADVVVYSSAVKPDNPEMIKAKQLGIPTIPRGEMLAELMRFKYGIAIAGSHGKTTTTSMVGTVLGKTGFDPTVVIGGKLEAYGSNAKLGRGEFLVTESDESDGSFLKLTPTIVSINNIDLEHIGFYKDLEDIKKAFVAFANKVPFYGAAAVNIDDENVKSILPYIERKVIKFGFSEDADIRAYDVRLENGRYKFKVNDFGEIHLSVPGIHNVYNALATIAICNELSVPFCVIKESLENFKNAKRRFEIKYSNDIIVIDDYAHHPTELKATLSAARDYFKDRRIIAVFQPHRYSRLNALFEEFAKAFDIPDITIVTEVYSAGESPIENVSGEKLAEKIREYGNNVYYVSNLEEAENLLKNIIQKGDVILTLGAGSITQLSDTLAKYLSEKE
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RADA_METMI
Sequence: MADVLTELPGVGPSTADKLIEGGYLDFMKIATATIGELTDIEGISEKAAAKMIMAARDLCDLGFKSGVELLKQRQSVWRLSTGSTELGTVLAGGIESQSVTEFAGMFGSGKTQIMHQTCVNLQMREKIFADLEGVVEEELEAPKAVYIDTEGTFRPERVVQMAEGAGIDGQTVLDNTFVARAYNSDMQMLFAEKIEDLIKGGNNIKLVIIDSLTSTFRNEFTGRGKLAERQQKLGRHMATLNKLADLYNCIVLVTNQVAAKPDAYFGVAEQAIGGHVVGHAATFRFFLRKSKGDKRVAKLYDSPHLPDSEAVFRITEKGIQD
What is the function of this protein?
Involved in DNA repair and in homologous recombination.  Binds and assemble on single-stranded DNA to form a nucleoprotein filament.  Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
What are the official names of this protein?
DNA repair and recombination protein RadA.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RecA-like protein family.
Protein: FLO8_YEAS6
Sequence: MSYKVNSSYPDSIPPTEQPYMASQYKQDLQSNIAMATNSEQQRQQQQQQQQQQQQWINQPTAENSDLKEKMNCKNTLNEYIFDFLTKSSLKNTAAAFAQDAHLDRDKGQNPIDGPKSKENNGNQNTFSKVVDTPQGFLYEWWQIFWDIFNTSSSRGGSEFAQQYYQLVLQEQRQEQIYRSLAVHAARLQHDAERRGEYSNEDIDPMHLAAMMLGNPMAPAVQMRNVNMNPIPIPMVGNPIVNNFSIPPYNNANPTTGATAVAPTAPPSGDFTNVGPTQNRSQNVTGWPVYNYPMQPTTENPVGNPCNNNTTNNTTNNKSPVNQPKSLKTMHSTDKPNNVPTSKSTRSRSATSKAKGKVKAGLVAKRRRKNNTATVSAGSTNAGSPNITTPGSTTSEPAMVGSRVNKTPRSDIATNFRNQAIIFGEEDIYSNSKSSPSLDGASPSALASKQPTKVRKNTKKASTSAFPVESTNKLGSNSVVTGKKRSPPNTRVSRRKSTPSVILNADATKDENNMLRTFSNTIAPNIHSAPPTKTANSLPFPGINLGSFNKPAVSSPLSSVTESCFDPESGKIAGKNGPKRAVNSKVSASSPLSIATPRSGDAQKQRSSKVPGNVVIKPPHGFSTTNLNITLKNSKIITSQNNTVSQELPNGGNILEAQVGNDSRSSKGNRNTLSTPEEKKPSSNNQGYDFDALKNSSSLLFPNQAYASNNRTPNENSNVADETSASTNSGDNDNTLIQPSSNVGTTLGPQQTSTNENQNVHSQNLKFGNIGMVEDQGPDYDLNLLDTNENDFNFINWEG
What is the function of this protein?
Required for diploid filamentous growth, haploid invasive growth and flocculation.  Putative transcriptional activator of FLO1 (By similarity).
What are the official names of this protein?
Transcriptional activator FLO8, Protein PDH5.
What is the protein family that this protein belongs to?
Belongs to the FLO8 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYCB_CLITE
Sequence: MGTIARYYAHVVLFLVATSVIFTVKKTEAGVPCAESCVWIPCTVTALLGCSCKDKVCYLNHVIAFEAKTMDEHHLLCQSHEDCYKKGSGNFCAPFFNHDVKYGWCFRAEFEGYLLKDFLKMQPRDILKISKAIAK
What is the function of this protein?
Probably participates in a plant defense mechanism.
What are the official names of this protein?
Cyclotide cter-B.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Bracelet subfamily.
Protein: SPKAP_RAT
Sequence: MDVNSRLSVQSNVESPLMPEDSEPQQITSSAAGSLAGSITACKKVLRSNSLLESTDYWLQNQRTPCQIGFVEDESENCASVCFVNLDVNKDGCSTENLQQKLVNVSPDLPKLINSMNVQKPKENEIVLLSGLASGNRQADFDVSQCPWLPDICLVQCARGNRPNSTNCIIFEINKFLIGLEVVQERQLHLETSVLKLEDDTNCSLSSIEEDFLTASEHLEEEIEVEDCKSGLETINVSANVLESKRPKEATQEGWDYHKEILHCALGEKHIRKHRMPSMKTERSKENTAENTALQSLNPSARPSRLKSEVAGSKQPATNYSYPENIRGEIETSQMLFIPRDAYLSMVSSCGVLTEQGSNHRDHDATPNSLPPVQNGEATAGEYATNLAESVMQDAFIRLSQSQPTLPQESAVSFSVGSALLPSGCCTKDMVVPRSWNELPKIVIVQSPEGSDTAPEPSVSSWPDLEVSVETPGIFSEESSSRPTQSALEVALACAATVIGTTSSPQATERFTMEQESLVSTYTQRGNGIQQTPVPRVFMGPSTTEYSFPSALCGMTQVASAVAVCGLGEREEVTYSVAPSDLLPTPGASEERSSIGSLVTEESTELGKEAIAEALLREATLVLARPNAYSSVGELLESVNRRIIETTSKTQMLCTENVRRNELAHTLSNVILKHSIDELHQKNIMAHPTEERHPGGTLNTLMESVNQLLHNVMCFTFRKMNHIVTLGEHPSFDKAAGHAWVKASACSSSHPSSNAHGTGLVIRDLVEDASPKPDKGGARPELVNNPRLQSEFSCSHRMLDSTARTFPKEMYPKGIVGEDTRNPLHTLSYDSSEQRTSTDIGKLTTVGEVRSTFQESEDSIVPKAQEKHTCATTLNNEAQINLSLLGDDLVVPDQSTLEAKQSEVYGITNFAEELAETVVSMATEIAAICLDNSHGKQPWFCAWKRGNEFLMTPNASCRSLKRKKENSGTGSTVRKHKPPRLSEIKRKADEHPELKEKLMNRVMDESMNLEDIPDSVSTFANEVAAKIMNLTEFSTVDGVWQTQSCSRNRLLGGDRWNRLKASSCESIPEEDSEARVFVNSLGLMSTLSQPVSRASSVSKQSSCESITDEFSRFMVKQMENEGRGFELLLDYYAGKNASSILNSAIQQACQKNDHLNVRPSCPSKQSSTESITEEFYKYMLRDIAKENKDGALSRRSSHDWSTGLLSPSARSPLCYRQSSMPDSRSPCSRLTVNAPIKANSLDGFAQNCPQDSINVQPVSRASSSGLCKSDSCLYRRSGTDQITNMLIHETWASSIEALMRKNKIIADDGEAANASPGPVSGGSPSQVEKCANRLVTGTGHKGPALLVQESVDYQRKDAVTEGNCSPVSSPSKMAPVKKPSGFDPTRETSACHNAVALKSPRRSLCSREVPLIQIETDQKEECVGESETLLPQSGSLEEAEGPQPEETIPDVARSEDTALSACQSSQDSLETREELEVDVLKEDITLDESRNPPSSSEESTGSWSQLANEEDNPDDTSSFLQLSERSMSNGNTSGTSSLGIMDLDIYQESIPSSPMINELVEEKEILKEQSESVKERASGLPGRAASPQRSLLVINFDLEPECPDAELRATLQWIAASELGIPTIYFKKSQESRIEKFLDVVKLVHQKSWKVGDIFHAVVQYCKMHAEQKEGTPSLFDWLLELG
What is the function of this protein?
Anchoring protein that binds preferentially to the type I regulatory subunit of c-AMP-dependent protein kinase (PKA type I) and targets it to distinct subcellular compartments.  May act as a converging factor linking cAMP and sphingosine signaling pathways.  Plays a regulatory role in the modulation of SPHK1 (By similarity).
What are the official names of this protein?
A-kinase anchor protein SPHKAP, SPHK1-interactor and AKAP domain-containing protein, Sphingosine kinase type 1-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the AKAP110 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Colocalizes with SPHK1 in the cytoplasm.
Protein: CYB_CEPGR
Sequence: MAPNLRKSHPLLKIINNSLIDLPTPSNISAWWNFGSLLGICLLTQILTGLLLATHYTADTTLAFSSVAHTCRNVQYGWLIRNLHANGASFFFICIYLHIGRGFYYGSYLNKETWNTGVILLLTLMATAFVGYVLPWGQMSFWGATVITNLFSAIPYIGQTLVEWAWGGFSVDNPTLTRFFALHFLLPFMIAGLALIHLTFLHESGSNNPLGILSNCDKIPFHPYFSLKDILGFIIMFLPLTTLALFSPNLLGDPENFTPANPLITPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASVLVLFLTPLLHKSKQRAMTFRPLSQLLFWTLVTNLCILTWVGSQPVEHPFIIIGQLASLTYFTILLLLFPIIGALENKMLNY
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RS19_HUMAN
Sequence: MPGVTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDENWFYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVMPSHFSRGSKSVARRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAANKKH
What is the function of this protein?
Component of the small ribosomal subunit (PubMed:23636399).  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399).  Required for pre-rRNA processing and maturation of 40S ribosomal subunits (PubMed:16990592).  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797).
What are the official names of this protein?
40S ribosomal protein S19, Small ribosomal subunit protein eS19.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS19 family.
What are the subcellular locations of this protein?
Nucleus. Note=Located more specifically in the nucleoli.
Protein: COXX_PROM1
Sequence: MVSSTSELITQPVNREEVVPSRKRIKLPAWLEVVKPRLIPLLLATTVGGMALSEEWPLPSPRLACTLGGGALAAAAAGALNCLWEQDLDKRMKRTSNRALPSGRLSQSSVFIGAVACTLVSSALLVSGVNCLAAGLTLLGLCSYVLLYTAFLKPRTSQNIVFGGVAGAIPPLVGASAAAGHIGLGGWWLFSLVMVWTPAHFWALAILLKEDYRSVGIPMLPTVSGPFVTAKAISVYGYLTVFLSFLGCFVLPEGGLLYGILLLPYNSRLLQLVSRLRDNPEDLDRAKGLFRWSILYMFGVCFLLVISRLQVSIVFNDQLIALIKDFSIGFS
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.