PharMolix/UniProtQA huggingface dataset:
Protein: RXL17_HYAAE
Sequence: MQSILWFALIASVVFLVLVDLASGLNGLETLSSGADVDELTTATRLLRAAHLDRKLSEERAFISGESIGSWWTKVTEWLRVKFELIIAYIKQLRVKSNDVKDDAATNDAAHAKDDAAANKAARAKDDASRATYEAARANYEAARAYDDATRAQDVAALEAARAIEATDIAAYTGANAEYEQSMFLNGFVKTIDLHNEKNAPIMTRLNKSLDEAKKSSTFREIADGVNESKVALVVHEKQDGYLLWILHLKWAVEAKSPKDVVERILKDLGTHDVPHLQERAEQVKKAYTIFLLYVERMSRATHPK
What is the function of this protein?
Secreted effector that confers enhanced plant susceptibility during both compatible and incompatible interactions between the pathogen and its host (PubMed:22072967, PubMed:21914011).  Promotes the sexual reproduction of the pathogen in the plant host (PubMed:21914011).
What are the official names of this protein?
RxLR effector protein 17.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cell membrane. Note=Localizes to the membrane around haustoria also called extrahaustorial membrane (EHM) at early and late stages of infection.
Protein: RL333_LACLA
Sequence: MRVNITLEHKESGERLYLTQKNKRNTPDKLELKKYSKKLRKHVIFKEVK
What are the official names of this protein?
50S ribosomal protein L33 3.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: TRAB_SINFN
Sequence: MRRDHLQPRLLTIASIVVGTVGWSGYALLLPVALAFPILWSRARTRRVAALVSAGYFLAASRGLPQGVAAFYTSDLWPGLLLWLCASGSFVVVHTVLWTKRSDCRPFRYLLAAVLMAVPPMGITGWAHPVTAAGILFPGWGWWGLVATTAGLMGLVTRMWPAVAIAFTGFWLWSAANWTESKLPASWQGVDLKLGSTLGRNTSIQRHRDLIATVKDRASGGVRNVVLPESALGFWTPTFERLWVKALQGTEISVISGAAAIDATGYDNVLVTLSADGGRVLYRERMPVPGSMWQPWGSWLGESDGARAHFFANPVVTVGNSRVAPLICYEQLVVWPTLQSMLYEPDLIVAVGNGWWTKGTSIVAIQRVNAIAWAKLFAKPLVLSFNT
What is the function of this protein?
Enhances conjugal transfer of the plasmid.
What are the official names of this protein?
Probable conjugal transfer protein TraB.
What is the protein family that this protein belongs to?
To A.tumefaciens Ti plasmid TraB.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: POTA_ACET2
Sequence: MERNVVIRLENVTKSFDDQVVLKNLTLDVRKNEFLTLLGPSGCGKTTTLRLIGGFEKPDEGIILHHGNDISNLPPYKRNVNTVFQKYALFPHLNVYENIAFGLKIKKMNKSLIKEKVEKALRQVNLVGYENRRIDQLSGGQQQRVAIARAIVNEPEILLLDEPLGALDLKLRQEMQYELKTLQKELGITFVYVTHDQEEALTMSDTVVVMNNGVIQQKGTPEDIYNEPVNAFVADFIGESNIVEGIMRQDGVVEIFGRVYECVDKGFAVNEKVDVVIRPEDIKLLEPSENKINGQVTSCIFKGVHYETCVMTDGFEWVIHNTKSFTPGENVSINVDPFDIHIMKKMEKEAGT
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: KTHY_MYCTU
Sequence: MLIAIEGVDGAGKRTLVEKLSGAFRAAGRSVATLAFPRYGQSVAADIAAEALHGEHGDLASSVYAMATLFALDRAGAVHTIQGLCRGYDVVILDRYVASNAAYSAARLHENAAGKAAAWVQRIEFARLGLPKPDWQVLLAVSAELAGERSRGRAQRDPGRARDNYERDAELQQRTGAVYAELAAQGWGGRWLVVGADVDPGRLAATLAPPDVPS
What is the function of this protein?
Catalyzes the reversible phosphorylation of deoxythymidine monophosphate (dTMP) to deoxythymidine diphosphate (dTDP), using ATP as its preferred phosphoryl donor.  Situated at the junction of both de novo and salvage pathways of deoxythymidine triphosphate (dTTP) synthesis, is essential for DNA synthesis and cellular growth.  Has a broad specificity for nucleoside triphosphates, being highly active with ATP or dATP as phosphate donors, and less active with ITP, GTP, CTP and UTP.
What are the official names of this protein?
Thymidylate kinase, Thymidine monophosphate kinase, dTMP kinase, TMPK.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: FABH_XANOM
Sequence: MSKRIYSRIAGTGSYLPEKVLTNDDMSKIVDTSDEWIFSRTGIRERHIAADDQATSDLAYFASLKAMEAAGVTADEIDLIVIGTTTPDLIFPSTACLLQARLGNVGCGAMDVNAACSGFVYALSVADKFVRSGDAKTVLVVGAETLTRILDWTDRTTCVLFGDGAGAVILKADEETGILSTHLRADGSKKELLWDPVGVSVGFGEGKNGGGALLMKGNDVFKYAVKALNSVVDETLAANGYDAHDLDWLIPHQANLRIIEATAKRLDLPMEQVVVTVDRHGNTSSASVPLALDEAVRSGRVQRGQLLLLEAFGGGFAWGSALLRY
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_STRP2
Sequence: MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVYGAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLRWLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: TREF_ECOLI
Sequence: MLNQKIQNPNPDELMIEVDLCYELDPYELKLDEMIEAEPEPEMIEGLPASDALTPADRYLELFEHVQSAKIFPDSKTFPDCAPKMDPLDILIRYRKVRRHRDFDLRKFVENHFWLPEVYSSEYVSDPQNSLKEHIDQLWPVLTREPQDHIPWSSLLALPQSYIVPGGRFSETYYWDSYFTMLGLAESGREDLLKCMADNFAWMIENYGHIPNGNRTYYLSRSQPPVFALMVELFEEDGVRGARRYLDHLKMEYAFWMDGAESLIPNQAYRHVVRMPDGSLLNRYWDDRDTPRDESWLEDVETAKHSGRPPNEVYRDLRAGAASGWDYSSRWLRDTGRLASIRTTQFIPIDLNAFLFKLESAIANISALKGEKETEALFRQKASARRDAVNRYLWDDENGIYRDYDWRREQLALFSAAAIVPLYVGMANHEQADRLANAVRSRLLTPGGILASEYETGEQWDKPNGWAPLQWMAIQGFKMYGDDLLGDEIARSWLKTVNQFYLEQHKLIEKYHIADGVPREGGGGEYPLQDGFGWTNGVVRRLIGLYGEP
What is the function of this protein?
Hydrolyzes trehalose to glucose.  Could be involved, in cells returning to low osmolarity conditions, in the utilization of the accumulated cytoplasmic trehalose, which was synthesized in response to high osmolarity.
What are the official names of this protein?
Cytoplasmic trehalase, Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 37 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARNB_YERPB
Sequence: MQSFLPFSRPAIGSEEINAVANVLGSGWITTGPQNHQLETDFCQIFGCKHAIAVCSATAGMHITLLALGIGPGDEVITPSQTWVSTINMIVLLGAEPVMVDVDRDTLMVNAAAIEAAITPNTKAIIPVHYAGAPCDLDALRQISQRHGIPLIEDAAHAVGTRYRDQWIGEQGTAIFSFHAIKNITCAEGGLVATDDDELAARVRRLKFHGLGVDAFDRQIQGRSPQAEVVEPGYKYNLSDIHAAIAVVQLRRLPEINARRQALVASYHKALAHLPLQPLALPHYSHQHAWHLFMVRVDEERCGISRDQLMACLKDMGIGSGLHFRAVHSQKYYRERYPHLCLPNTEWNSARLCTLPLFPDMLDSDIERVANALTTIIGSHRVTK
What is the function of this protein?
Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase, UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase, UDP-Ara4O aminotransferase, UDP-4-amino-4-deoxy-L-arabinose aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.
Protein: MIO_DICDI
Sequence: MSQSSTRKRLIQWSPHNKSSFIVGSNDLRLYNFKFKDKNEKKNENNINNSNQYNQNNQQQQQQQIQQQQQQQQQQQQQQQQQQQQQQQQQQQQHDIYSPKSITSKYMETYNFDIEYPPDDWVPQEKKTISLMSVNSDVQLMKCMAWCPDESDTNLIACGLTSGRAILTSFSSVNRILKELVPKHTRSCNAISWNPIYTNQLAVGLDKVRGDSSTLIWDINYLQSTTLNNHLHKNNNNYISKLQQQQNNIDQPYIISQISDNSFSTSTDYTDTIYQPISEFTQSEATLALAWLPNNPSCLLVGTGSKWLKLYDIRDVNSSQSVMAHQKSVNGVCVDPFDFNRIATMSEDSHIKVWDLRNLDDPLIIVNSNCKSIQQIDWCPTRSGVLASVGKDKSSIKLWDIKAPIEFSKSPKLESTTLSTGGGGSGSNTSNNLNKRSTSNNNNSQDPINTISKPTKIHHSSDVVSSFSWHPTNECRMLTVSYSGVIDVVSLNENIPISWSPHGGICFSFGNNVLEGPTKGETLEPNILNYKNLINDGRYEKDISSKIKERAIFGYSANVEENINLANKINDENINFLWKWIQKVPIQIQNFKRESSLISTPSISTTTPGGPITPSATTKTIINNNNNNNNNKNINNNINNINNNNNNNNNNNNNNNNNNNNNNNNNNNNNEYNGIYNILIEKDISTVESSNGFVIYKSPNRNLCLSICGWGFNQSLPLENILSRLEKSGEYERAAAIAVFHLDIKRAILVVTNATYNIHPVTQTNHHGHLMRQDREFSLKLLSIALAGFDGSSTSNNNNNNNNNNNNIWKETCKSTAKSFINPYLKTCLEFLASNSDSKDIYSIIEDSRINLDDKIAFSCKYLDYQDLIHFVERNTIRVIECGNLKGVLLTGLTGRGVDLLSNYIDRTCDIQTAVLAISLVVPKFFRDKRVSKWSSIYSDLLDQWELWHERAILDIQTRISGIDQPPTPQIFAKCGFCQNSFAFESISASSIVGRNASSKPNFKAKVPFCPHCKQSLPRCCLCLLPLNCMVPTPEFKKSNTTIGSGGGSIASSGGINNSGSINNPNDSQLWSNGSEPFEDWFTWCQTCRHGGHSQHILDWFKDHSICPVTSCDCRCSQL
What is the function of this protein?
As a component of the GATOR complex may function in the amino acid-sensing branch of the TORC1 signaling pathway.
What are the official names of this protein?
GATOR complex protein MIOS.
What is the protein family that this protein belongs to?
Belongs to the WD repeat mio family.
What are the subcellular locations of this protein?
Lysosome membrane.
Protein: NADD_BACC1
Sequence: MRKIGIIGGTFDPPHYGHLLIANEVYHALNLEEVWFLPNQIPPHKQGRNITSVESRLQMLELATEEEEHFSICLEELSRKGPSYTYDTMLQLTKKHPDVQFHFIIGGDMVEYLPKWYNIEMLLNLVTFVGVARPGYTLHTPYPITTVEIPEFAVSSSLLRERYKEKKTCKYLLPEKVQVYIERNGLYES
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: KU70_YEAST
Sequence: MRSVTNAFGNSGELNDQVDETGYRKFDIHEGILFCIELSETMFKESSDLEYKSPLLEILESLDELMSQLVITRPGTAIGCYFYYCNREDAKEGIYELFPLRDINATFMKKLNDLLEDLSSGRISLYDYFMFQQTGSEKQVRLSVLFTFMLDTFLEEIPGQKQLSNKRVFLFTDIDKPQEAQDIDERARLRRLTIDLFDNKVNFATFFIGYADKPFDNEFYSDILQLGSHTNENTGLDSEFDGPSTKPIDAKYIKSRILRKKEVKRIMFQCPLILDEKTNFIVGVKGYTMYTHEKAGVRYKLVYEHEDIRQEAYSKRKFLNPITGEDVTGKTVKVYPYGDLDINLSDSQDQIVMEAYTQKDAFLKIIGFRSSSKSIHYFNNIDKSSFIVPDEAKYEGSIRTLASLLKILRKKDKIAILWGKLKSNSHPSLYTLSPSSVKDYNEGFYLYRVPFLDEIRKFPSLLSYDDGSEHKLDYDNMKKVTQSIMGYFNLRDGYNPSDFKNPLLQKHYKVLHDYLLQIETTFDENETPNTKKDRMMREDDSLRKLYYIRNKILESEKSEDPIIQRLNKYVKIWNMFYKKFNDDNISIKEEKKPFDKKPKFNI
What is the function of this protein?
Single-stranded DNA-dependent ATP-dependent helicase.  Involved in non-homologous end joining (NHEJ) DNA double strand break repair.  DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA.  Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection.  Appears to have a role in recruitment of telomerase and CDC13 to the telomere and the subsequent telomere elongation.  Required also for telomere recombination to repair telomeric ends in the absence of telomerase.  KU70, of the KU70/KU80 heterodimer, binds to the stem loop of TLC1, the RNA component of telomerase.  Involved in telomere maintenance.  Interacts with telomeric repeats and subtelomeric sequences thereby controlling telomere length and protecting against subtelomeric rearrangement.  Maintains telomeric chromatin, which is involved in silencing the expression of genes located at the telomere.  Required for mating-type switching.
What are the official names of this protein?
ATP-dependent DNA helicase II subunit 1, ATP-dependent DNA helicase II subunit Ku70, High affinity DNA-binding factor subunit 1.
What is the protein family that this protein belongs to?
Belongs to the ku70 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: YFT2_SCHPO
Sequence: MSFSRNQVLKGLKTKKAKPKKNPTVDELFEIAIDLEESGDRWRLEPAKCLRFYQKSLETYDRYLLQCPNDFDARFNKARLLLNMATNCDMLYKDSQVCLQKSIEMHKHALLLQEAPDIWFNLAQVHLNLAEIWVDLDREDLAYPEIQQALQSISHSIDLQERERIEWENTIQTSSQQKYEEIPDIQARRLYFIEADKEASTLVTEIASLACSCKLLEESDFEKLCQIMLPITEKLDILKLMDWYLAKTKRLVLGGKENEVAWIDLLQVFDHQLSQLPQLNLQNPLDPNSSVKPLHIQLLCDKADAYIDFAETLLDSCVSTEESASIEIMTRAWNMLGVAAKSLKMANTYNPNHVRILISRADLEIQRAAIPIMVAQNSKLVLYKNAKVLYEKAFRDYSTKKTTRTFAEIVLKHYQLQKLTNPETIKMLDSLTEVAQEDILNTI
What are the official names of this protein?
UPF0656 protein C926.02.
What is the protein family that this protein belongs to?
Belongs to the UPF0656 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ACP_HYPNA
Sequence: MSDVFERVKKIVVENLDVEADKVVESASFIDDLGADSLDLVELVMAFEEEFNIEIPDDVQESIRSVGDAVSHIKAHV
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTAD_NATPD
Sequence: MSTLQITGGQVLTPELTVRTADVLADSETGEILAVGDTAAGDRTLDAEGCLVVPGLVNTHCHAAMTLLRGYADDKPLDRWLQEDIWPVEAELTPEDIRAGTRLGLVELLKNGVTAVGDMYFEVPEVAAAVEEAGIRARLGHGIVTVGKDEADARADFEEGLAVARELDGAADGRVRTALMPHSLTTADPDLIAEFVPRARDAGVPIHYHANETTDEVDPIVDERGVRPLEFADELGLLDEGDFIAHGVHVDETEIELLAERGVGVAHCPASNMKLASGIAPVQEFLDAGVTVGIGTDGPASNNDLDVVDEMRDAAMVGKLGADDAAAVAAPDIVNAATAGGAETLGFDAGRVEAGALADLAIVDLDAPHLTPSHDLVSHLAYAVRGSDVRHTVVGGEVIVEDREVRTLDAGAVKREAERHAAELVSRAEGD
What is the function of this protein?
Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively.  Is also able to deaminate adenosine.
What are the official names of this protein?
5-methylthioadenosine/S-adenosylhomocysteine deaminase, MTA/SAH deaminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
Protein: RECR_CHLFF
Sequence: MLKYPDYLSKLISFLRKLPGIGFKTAEKLAFELLDWEQDQLEALGKAFSELSIARSHCPCCFCLKNFPESQCEFCQNNRDTSTLCIVASPKDIFSLERSQVFKGHYYVLGTLLSPLTGKHIEEERMRLLKQRIEFLNPKEIILALDATLEGDATALFLKQELAYSLASISRLALGLPIGLSFDYIDSGTLARAFSGRNPY
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: RIMM_MANSM
Sequence: MNKMDRQRIETVGKLGSTYGIRGWLRIYSSTENAESIFDYQPWFLKIKDQWQAIELETWKHHNHELIVKLKNINDRETAQTLANVEIGVDLSVFPALEEGDFYWHDLIGCQVVNLQGYAMGTVSEMMETGSNDVLVVRANAKDAFGKQERLIPFLYEQVVKRVDLTTKTIEVDWDAGF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DJC25_XENTR
Sequence: MAALGKAEESQGCFGLFLLLPGPSMQPRLFVLVALSVLLLSGRAGALTEGLYCGRQVCYDVLGVSRDASKGDIARAYRQLARKYHPDRYRPGEPPGPDGETRESAQEKFLLVATAYETLKDEETRKDYDYMLDHPEEYYRHYYHYYSRRLAPKVDVRIVILVSVCAISIFQYYSWWSSYNEAINYLATVTKYRIQAMEIAKQQGLLNRTKEKGKNRRSKEEIKSEEEEIIRDIIKNKIDIKGGYQKPQIFDILLFQIILFPYYIFKYISWYVHWIYTFNIQGKEYGEEEKLYLIRRNMKMSQSQFDTLEEHRKNSFLEQKLWIKENYEVYKLEQEEEMKKKMASDPRWKRYRRWMKNEGPGRLTFADD
What are the official names of this protein?
DnaJ homolog subfamily C member 25.
What is the protein family that this protein belongs to?
Belongs to the DNAJC25 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RSME_HELPY
Sequence: MRFVYHPLAKEPVLKIEGESYTHLYRSRRVKSASRLDLRNLKDGFLYTYEHAEITKKHALLKLVGARLLEVMASKKTHLILSVIEIKNIEKILPFLNQLGVSKLSLFYADFSQRNEKIDIAKLERFQKILIHSCEQCGRSALMELEVFSNTKEALKAYPKASVLDFKGETLPASADFEKGVIIGPEGGFSEPERGYFKEREIYRIPLDMVLKSESACVFVASIAQV
What is the function of this protein?
Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA.  Acts on the fully assembled 30S ribosomal subunit (By similarity).
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase E, 16S rRNA m3U1498 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RsmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y146_MYCPN
Sequence: MLASCGAKGRFDQVDDGKIKLASSLTGKRDVILQEVLNKYNSRKAKDDYPIEITKIAGSYDGGRSDLQTRLSVKDKTTFYNMILNYSDTISTLGRSNMELPLDSVDVSQFSENFLSFNDRISGISRKGIYGIPVSMSTDILVINGPVLHYILNSAKKKDGAVTKKNASNSNGNEGTLTVNNDQQTTELWKKIEEAAKTNGKTTQEQTKRDAKQSTSLIQLKEGSANTTEGNASESDKEIKKSWGNYQEVDGGLKGYTFKASVFEN
What are the official names of this protein?
Uncharacterized protein MPN_146.
What is the protein family that this protein belongs to?
Belongs to the MG185/MG260 family.
Protein: FUCL6_ANGJA
Sequence: MKTCNLTDRMKVKMIMLLFQILAISTLQSVSAYIPDRYIQENVAVRGKATQSDQLQGQWDAFSHASNAIDGNQDSYFYHGSCTHTSGGANPWWRVDLLQEYKITSVTITNRGDCCGERITGARIIIGKNNGLNNPECSTVGIMTAGETKTFRCSHPMIGRYVTVYLPKTEYLHLCEVEVNAMLPAN
What is the function of this protein?
Acts as a defensive agent.  Recognizes blood group fucosylated oligosaccharides including A, B, H and Lewis B-type antigens.  Does not recognize Lewis A antigen and has low affinity for monovalent haptens.
What are the official names of this protein?
Fucolectin-6.
What is the protein family that this protein belongs to?
Belongs to the fucolectin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRPE_METTM
Sequence: MGVNVFGIINLEKPRKEKLEFREPFEVFKSIYSEYESSFLLESMESDTGLARYSFIGFEPEMIIRAREGVIEIDDGDSREEFDSKNPFEDLRGFLKMEKNSGGFCGGLVGYISYQAARFFDTIRLSEGDFPDFEFGLFLDGIMFNHLTGECSYISRHGNRLPDISPLLGDEVPTGTLGYRRERTLLSKRRYMDMVLEAKERIREGEIFQAVLSSATDYRLRGDRLAFYESLRRINPSPYMYHLKLGEREITGSSPEMLVRVEDRRIETFPIAGTRPRGRTEEEDGVIASDLLSDEKELAEHLMLVDLARNDIGRVSEFGSVEVPEYMTIKRFSHVQHILSHVTGKLRDGMDAVDALGAVFPAGTVSGAPKIRAMEIIESLEGVPRNAYAGALGYLSLNGNADFAITIRSMVCQGKTGRIQAGAGIVHDSIPEMEYLECQNKARALLKSMEMAGEQVDPDNR
What is the function of this protein?
Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan.  In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate.  In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia (By similarity).
What are the official names of this protein?
Anthranilate synthase component 1, AS, ASI.
What is the protein family that this protein belongs to?
Belongs to the anthranilate synthase component I family.
Protein: Y1183_STRPJ
Sequence: MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEEFGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEILTSIDNRE
What is the function of this protein?
Might take part in the signal recognition particle (SRP) pathway.  This is inferred from the conservation of its genetic proximity to ftsY/ffh.  May be a regulatory protein.
What are the official names of this protein?
UPF0122 protein SPN23F11830.
What is the protein family that this protein belongs to?
Belongs to the UPF0122 family.
Protein: VASP_DICDI
Sequence: MSETAIFNATGQVFTYSPQTRNWVPSSNVPATLQMYFNSGANTYRVIGRAGDDPNNFLINFAVKSEVVYSRASEIFHQFTDQRTHFGINFTSKQDADTFGGGFENVLRSLKGGPQQPPPQVPKPQPQQPPQPQQPPQRPPSTVIAKPVAPQAPVAPPQAPAAAPQAPAPPAAPPAPPKPPGPPPPPPAPKPPAAGGGTGRNALLGSIENFSKGGLKKTVTVDKSAGVPTKTTPSANSAASNAGSEPSSGGSTPAPAPKSSGGGGGGDLMAEVMAKRAKMKAAASQPKEESSAPTPAPTPAPTPAPTPSSTSFKPPQSFSKPATKTAAANKPPSPSLSAPLPSTVANEDLQSLKEEILTEVRKEIQKAKDEILEAIRASQH
What is the function of this protein?
Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as lamellipodial and filopodial dynamics in migrating cells.  Plays a crucial role in filopodia formation, cell-substratum adhesion, and proper chemotaxis.  Nucleates and bundles actin filaments.  When complexed with fotH in filopodial tips, may support formin-mediated filament elongation by bundling nascent actin filaments.
What are the official names of this protein?
Protein VASP homolog, DdVASP.
What is the protein family that this protein belongs to?
Belongs to the Ena/VASP family.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Cell projection, filopodium. Cytoplasm, cytoskeleton. Note=Localizes to the leading edge of migrating cells and to the tips of filipodia. Translocates to the cell cortex in response to cAMP chemoattractant stimulation.
Protein: TDXH_METMA
Sequence: MPLIGDDAPSFTAVTTQGIIKFPDDYKGKWVILFSHPADFTPVCTTEFMTFASMQEEFRSMNTELIGLSIDSVFSHIAWLKRIEEKIEYKGMKNLEIKFPVIEDLKMDVAKKYGMVQPKASTTQAVRAVFIIDPEAKIRTILYYPQSTGRNMQEIKRIVVALQKNAAEKVATPANWQPGEDVIIPPPSSMEAVKERMGKEEEGKRCLDWFMCLKKDTQK
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Peroxiredoxin, Thioredoxin peroxidase, Thioredoxin-dependent peroxiredoxin.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. Prx6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KLH33_HUMAN
Sequence: MLLSGMRESQGTEVSLRTISTQDLRLLVSFAYSGVVRARWPGLLRAAQAALQYQSSSCLDLCQKGLARGLSPARCLALFPMAEAPGLERLWSKARHYLLTHLPAVALCPAFPSLPAACLAELLDSDELHVQEEFEAFVAARCWLAANPETQESEAKALLRCVRFGRMSTRELRRVRAAGLLPPLTPDLLHQLMVEADVPGQERRREPDRALVVIGGDGLRPDMALRQPSRAVWWARAFRCGVGLVRTVEWGQLPALPAPGRFRHGAASLAGSELYVCGGQDFYSHSNTLASTLRWEPSQEDWEEMAPLSQARSLFSLVALDGKLYALGGRHNDVALDSVETYNPELNVWRPAPALPAPCFAHAAAILEGQLYVSGGCGGTGQYLASLMHYDPKLEKPGTFLSPMGVPRAGHVMAALGGRLYVAGGLGETEDLLSFEAYELRTDSWTHLAPLPSPHVGAASAVLQGELLVLGGYSHRTYALSHLIHAYCPGLGRWLCLGTLPRPRAEMPACILTLPAVQHIALVPTPHQTKPAG
What are the official names of this protein?
Kelch-like protein 33.
Protein: HOLIN_BPHC1
Sequence: MNSKIDSAIPFIGSLTALISGYSLHEWASLFGILFGAVSVWIAYRKYKEDVQARKDELAYKMLVAKIEAKKLGIAIDE
What is the function of this protein?
Accumulates harmlessly in the cytoplasmic membrane until it reaches a critical concentration that triggers the formation of nanometer-scale pores (pinholes) causing host cell membrane depolarization and endolysin refolding and release into the periplasmic space (By similarity).  Once the pinholin has permeabilized the host cell membrane, the SAR-endolysin is released into the periplasm and breaks down the peptidoglycan layer (By similarity).  Determines the precise timing of host cell lysis.  Participates with the SAR-endolysin and the U-spanin protein in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles from the host cell (By similarity).
What are the official names of this protein?
Holin, Pinholin.
What are the subcellular locations of this protein?
Host cell inner membrane; Multi-pass membrane protein.