PharMolix/UniProtQA huggingface dataset:
Protein: PGLRX_ASPTN
Sequence: MKFLHTVAQTATLLLSLGASVEGFNRARNDACKPHHPFRPLPASTPRTKTCHVRSHGDGTDDAAFVLSALRKCNNGGKVVFDADKEYTIGTALDMTFLRHVDLEILGRIQFTNDTDYWQAHAFRHGFQNATTFFQLGGTDVNVYGSGTLDGNGQVWYDLYAAEPLTLRPILLGVIGLHGGTIGPLKLRYSPQWYQLVANSTDVLFDGIDISGYSSSKNTAKNTDGWDTYRSSNIVIQNSVVNNGDDCVSFKPNSTDILVQNMHCNGSHGISVGSLGQYKGEIDIVKNILVYNISMYNASDMARIKVWPGVDSALSEDLQGGGGSGAVSNITYDRMYIENVDWAIEVTQCYGQKNQTLCNQYPSNLTISDVHIKNMWGTTSGKRDPNVGTIVCSSPDVCSDIYVTNVNVTSPSGTDDYICTNVDESLLDVNCSSG
What is the function of this protein?
Specific in hydrolyzing the terminal glycosidic bond of polygalacturonic acid and oligogalacturonates.
What are the official names of this protein?
Probable exopolygalacturonase X, ExoPG, Galacturan 1,4-alpha-galacturonidase, Poly(1,4-alpha-D-galacturonide)galacturonohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted.
Protein: FTHS_LIMF3
Sequence: MLTDIEIADQAQLTPINEIAAQLGLDEDAIEQYGKYKAKINLPVQATPEKKHKLVLVTSINPTPAGEGKSTVLVGLGDALSLLHHQTVIAMREPSMGPVFGMKGGATGGGYSQVVPMEDINLHFTGDFHALTSANNTLAALIDNYLMRGNELGLDPRRVIWKRVEDVNDRALRDVVTGLGGIMQGVPRQTGFDITPASELMAILCLATDLSDLKARVSRIVVGYTYDKEPVTVGQLGFEEAVTILLKDAIKPNLVQTLGHTPAIVHGGPFANIAHGCNSVLATKTALQLADYTVTEAGFGADLGAEKFLDIKRPVLGKTPDAVVIVATVRALEYNGGASLQALKDENLTELENGLQNLNRHIANMQRYGLPLVVAINHFATDTPAEIKLIEDNCKARGVNVVVADAWAKGGAGTLDLAKEVVALAEQEASFTPLYDYQATPKEKVETIATKVYGAGRVAFSKKALNQLKQFEKLGWNDLPICIAKTQYSFTDDQTQLGAPEGFTFHIREFVPKLGAGFIVALAGNMLTMPGLPKVPAAVKMTIDSEGKITGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: RIBBA_THEPX
Sequence: MFDRIEDAIEDIKQGKMIIVVDDENRENEGDLVMAAEKVTGEHINFMIKYGRGLVCVPMTEKRLNELGIYQMVENNTDHKETAFTVSVDYKECTTGISAFERALTVKKLVDDNSKPEDFTKPGHIFPLRAKDGGVLVRAGHTEAAVDLAVLAGLKPAGVICEIIKDDGNMARLPDLLEFAKKFGLRIISIEDLIKYRMKNEILVRRVAQAKLPTKYGNFEIVGYEEILTGKQHVALIKGDVNKEPVLVRIHSECLTGDILGSLRCDCGDQLHAAMERIGQEGGILVYLRQEGRGIGLLNKIKAYHLQDQGLDTVEANIKLGFPPDLREYNIAAQILKDIGVKKIRIMTNNPQKITELSDYGLDVVERVSIEICPNHYNEKYLKTKKEKMGHLILEV
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
Riboflavin biosynthesis protein RibBA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the GTP cyclohydrolase II family.
Protein: RL25_CERS1
Sequence: MAGEIPDFQAEVRTGTGKGAARQARREGYVPGIVYGGGQEPLSINVPYNDLLNRLKKGRFLQTLFNLKVEGQEDVRVICRGVQRDVVKDLPTHVDFMRLRRTSRVNLFIHVTFENHDKAPGLKRGGTLTVVRPEVELEVTAGDIPDHLTVDLTDRQIGDVIHINDIKLPEGAVPTINRNFVIANISAPSGLRSSDNEEEAEEA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: S38AA_XENLA
Sequence: MAASNWGLIMNIVNSIVGVSVLTMPFCFQQCGILLGTLLLMLCTWMAHHSCMFLVKSASVSKRRTYAGLAFHAYGKVGKMMVETSMIGLMLGTCIAFYVVIGDLGSSFFARLFGLEVSEGFRVFLLFSVSLCIVLPLSLQRNMMAFIQSFSAMALMFYTVFMFVIVLSSFKHGLFSGQWLKHVSYIRWEGVFRCIPIYGMSFACQSQVLPTYDSLDDPSVKIMSSIFALSLNVVTTFYITVGFFGYVSFPETIAGNVLVNFPSNLVTEMIRVGFMMSVAVGFPMMILPCRQALNTLLFEQQQKDGTFTAGGYMPPLRFKILTLVVVFGTMLGGILIPNVETILGLTGATMGSLICLICPALIYKKIHKKGLASQFILGVGLLILVISTYTTLTVTEEPTQIKSELLERIDLKEEKDPEQINSQKSDEKAKVEQPGDNRDKPKLPPKNPEEEQIKGPIEGPQKEKDTKKQEEVQLDRPDQGDIAVPVGEAHRHEPPIPQDEVAVDEKKDQGEREEKKESVVDINSTEKKDKQQINLEKEPEIKDQAEANKGINEPVPQKPPQEVNDPNKQQLVNPPTPRLKEQPPFKDLEGIIKDLAVPVEIKKNAEIAEEKDNNDFANPVKAIENPPIKDEKNEQIPGDPGKESHVEPKAEDNQAEAGKAELLDHAFLLQVIKEQQVQQKRLLDQQEKLLEVIKEQHMEIHQQKGDEDQQDKLEGNIADKNKEELKAEARVAQKPLEGDKLENVGEVNAKVDKPAVEEHVVVVEKEQNPALNQVVKGNVPDVKKNDHKIEAPKINVEEVKVPISAGKHKKQSVQENLIHQQDVDQGASDNYKQREKAVAANKDYVLGHIIQQETANPIDPITLPDLQDKLGKLALHQTEPKQKPVKIAGIGEKKLGAVQEEKILVQKGQEAQADKVIQDNYNPVPDHGLHENNNADAPATINVEAKKEHIEKPKDGAVLEHDEGKQNRDLKLQNDMDLRRKKRDLALVQQENNGAQIISFHPVPNLKVNDLRGALEARLNQMVDGGLQVVQSRKIKQLIDEEKNR
What is the function of this protein?
Putative sodium-dependent amino acid/proton antiporter.
What are the official names of this protein?
Putative sodium-coupled neutral amino acid transporter 10, Solute carrier family 38 member 10.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y1505_DICT6
Sequence: MSGHSKWANIKHRKAAADAKKGKLFSQLSKEIIIAAKHGGGNPETNPRLRAAIERAKEANMPKENIEKAIMRGIGAIPGVAYEEVTYEGYGPGGVAIMVEVVTDNKNRTAAEIRRIFTKHGGSLGEAGCVAWIFEDKGSIFIEKESVKDEDQLIADALEAGAEDVQISGDSVEIITSPENFSEVKNVLEEKGYKITQAEVTKVPKNVVPVDGPDAEKVLKLMEELEDHDDVQKTYANFDIPDEILQSLS
What are the official names of this protein?
Probable transcriptional regulatory protein DICTH_1505.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MORC3_HUMAN
Sequence: MAAQPPRGIRLSALCPKFLHTNSTSHTWPFSAVAELIDNAYDPDVNAKQIWIDKTVINDHICLTFTDNGNGMTSDKLHKMLSFGFSDKVTMNGHVPVGLYGNGFKSGSMRLGKDAIVFTKNGESMSVGLLSQTYLEVIKAEHVVVPIVAFNKHRQMINLAESKASLAAILEHSLFSTEQKLLAELDAIIGKKGTRIIIWNLRSYKNATEFDFEKDKYDIRIPEDLDEITGKKGYKKQERMDQIAPESDYSLRAYCSILYLKPRMQIILRGQKVKTQLVSKSLAYIERDVYRPKFLSKTVRITFGFNCRNKDHYGIMMYHRNRLIKAYEKVGCQLRANNMGVGVVGIIECNFLKPTHNKQDFDYTNEYRLTITALGEKLNDYWNEMKVKKNTEYPLNLPVEDIQKRPDQTWVQCDACLKWRKLPDGMDQLPEKWYCSNNPDPQFRNCEVPEEPEDEDLVHPTYEKTYKKTNKEKFRIRQPEMIPRINAELLFRPTALSTPSFSSPKESVPRRHLSEGTNSYATRLLNNHQVPPQSEPESNSLKRRLSTRSSILNAKNRRLSSQFENSVYKGDDDDEDVIILEENSTPKPAVDHDIDMKSEQSHVEQGGVQVEFVGDSEPCGQTGSTSTSSSRCDQGNTAATQTEVPSLVVKKEETVEDEIDVRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETCHQSTETDAVFLLESINGKSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECSQCSNNESKSEMDEMAVQLDDVFRQLDKCSIERDQYKSEVELLEMEKSQIRSQCEELKTEVEQLKSTNQQTATDVSTSSNIEESVNHMDGESLKLRSLRVNVGQLLAMIVPDLDLQQVNYDVDVVDEILGQVVEQMSEISST
What is the function of this protein?
(Microbial infection) May be required for influenza A transcription during viral infection (PubMed:26202233).
What are the official names of this protein?
MORC family CW-type zinc finger protein 3, Nuclear matrix protein 2, Zinc finger CW-type coiled-coil domain protein 3.
Protein: VGR2A_PSEAE
Sequence: MRQRDLKFTFVVGEGKLAFDVVEFELEEALCEPFRLNLKLASDKNAIDFRQVLDQPGTFTLWQDGRPARYVHGIVSHFTQGSSGFRRTRYELLLEPQLARLELCCNWRIFQEKSVPEILQALLKEHRVLDYEQRIYHEHLPREYCVQAGDSDHYLHDRLAFEEGLVYYFRFDEHRHTLVCSDRLYVQERIAGGPVLFSAQPEGDNPQPVLHSFRYSENVRTARQTQRDYSFKRPTYDQEHHLAGEALEHQGSSYERYDYPGRYKRSGAGRPFSESRLRGHRRDARVASVSGDDPRLIPGHAFALEGHPRADFNAWWRPVRVVHRGTQYAGQEEESADAPLGVSYDLRAELVPEDVEWRPAPLPRPRIDGPQIATVVGPAGEEIHCDEWGRVKVQFPWDREGRHDEFSTCWIRVAQNWAGADWGHMAIPRIGQEVIVDYLDGDCDQPIVTGRTYRATNRPPYALPDHKILSTIKSKEYKGSRANELRIDDTTAQISAALMSDHGASALHLGYLTHPRPEGGKPRGEGFELRTDEHGAVRAAKGLLLSTEEQLRAGAGHLDRGVVVQVLEAALKLARELGDYAGEHQGVGHDAAPQQTLQEAVRDLGHGANDESGKSNGGKPAIALSGPAGIAAATPASLTLAAGEHVDSVARQNQQVTAGQKVVINAGSDIGLFAQGGELRQITHQGPMLLQAQKNDIRLEAEQSVEVSASQQHVLVTAKEHITLMCGGAYLTLKGGNIELGMPGNFVVKAAKHSHVGPAHASTSFNAWDSTPFDDRYVLRDEATLEPLPNIAVEVIRGDGGVVKLMTDSQGRLPKQQHLAMDPVQIRILGKGSHNSDTESNT
What is the function of this protein?
Part of the H2 type VI secretion system (H2-T6SS) specialized secretion system, which delivers several virulence factors in both prokaryotic and eukaryotic cells during infection (PubMed:26037124).  May form the spike at the tip of the elongating tube formed by haemolysin co-regulated protein 2a/Hcp2a.  In turn, may allow the delivery of the Tle4 antibacterial toxin to target cells where it exerts its toxicity (Probable).  Promotes also the release of VgrG2b toxin to the host cell (PubMed:26037124).
What are the official names of this protein?
Type VI secretion system spike protein VgrG2a.
What is the protein family that this protein belongs to?
Belongs to the VgrG protein family.
Protein: UVRB_SALA4
Sequence: MSKPFKLNSAFKPSGDQPDAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKALLERRDVVVVASVSAIYGLGDPDLYLKMMLHLTVGMLIDQRAILRRLAELQYTRNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQVESTVPRYTIYPKTHYVTPRERILQAMEEIKDELADRRKVLLANNKLLEEQRLSQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGEPPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYELEKSGDEVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDIDTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPSMAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGKGKGRSTAKAGIVELDMTPKALQQKIHELEGQMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_ROSS1
Sequence: MARIAGVDLPRNKRIEIAITYIFGIGRSNGAEVLRKANVNPATRVRDLTEEEVSRIREIVEREYRVEGDLRREIQMNIKRLMDIGCYRGLRHRKGMPVRGQRTRTNARTRRGRRGQAIGIKKKTVKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: GERPD_BACCR
Sequence: MNLNVVNRELKVGQIKMNGVSSSALFLIGDANLLILSSILDTPFETVTEGPFVPLVTDVPPTPG
What is the function of this protein?
Required for the formation of functionally normal spores.  Could be involved in the establishment of normal spore coat structure and/or permeability, which allows the access of germinants to their receptor (By similarity).
What are the official names of this protein?
Probable spore germination protein GerPD.
Protein: SYC_NEOSM
Sequence: MKLRVHNTLSGLKEEFFPLSSEVVRMYVCGPTVYDVPHIGNIRASVVYDIVYRVLLKLFPEVIYVRNITDVDDKIITAASVRGVKCDKVALHYEHIFHEHLGLLNCLSPTVEPKATQNIGKMISMIQALIDNGNAYSVGGNVYFDVGSFAEYGVLSKRKKEQLVYGVRVEKDVDKKHPGDFILWKSDDHVYWPSPWGNGRPGWHIECSAMTLATLGADFDIHGGGADLKFPHHENERAQSMCANPGSQFARYWVHNGFLTVNGEKMSKSLGNVVNVDTLVESGVTPNVIRFVLISTHYSKPLDWNDAMVGEAINSLIKFKLALLDSGVLPKSKSHIGSLNIGVCSDNAEDEEVDPRSCASEVIVARNKRKAKNFSKKMNEIFNKFGGLGDDCSIYTREFFECMADDFNTPGAIAVLHKLSDGVRLVGAEKVNNLAHLLYNLLIFLGIDLGVRQSSVSEDFIRSQLQKRADCKRQKDFVEADRIRFALAKMGVLIRDHKHAPTDWVSL
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KBAZ_ECO55
Sequence: MKHLTEMVRQHKAGKTNGIYAVCSAHPLVLEAAIRYASANQTPLLIEATSNQVDQFGGYTGMTPADFRGFVCQLADSLNFPQDALILGGDHLGPNRWQNLPAAQAMANADDLIKSYVAAGFKKIHLDCSMSCQDDPIPLTDDIVAERAARLAKVAEETCREHFGEADLEYVIGTEVPVPGGAHETLSELAVTTPDAARATLEAHRHAFEKQGLNAIWPRIIALVVQPGVEFDHTNVIDYQPAKASALSQMVENYETLIFEAHSTDYQTPQSLRQLVIDHFAILKVGPALTFALREALFSLAAIEEELVPAKACSGLRQVQEDVMLDRPEYWQSHYHGDGNARRLARGYSYSDRVRYYWPDSQIDDAFAHLVRNLADSPIPLPLISQYLPLQYVKVRSGELQPTPRELIINHIQDILAQYHTACEGQ
What is the function of this protein?
Component of the tagatose-1,6-bisphosphate aldolase KbaYZ that is required for full activity and stability of the Y subunit.  Could have a chaperone-like function for the proper and stable folding of KbaY.  When expressed alone, KbaZ does not show any aldolase activity.
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit KbaZ.
What is the protein family that this protein belongs to?
Belongs to the GatZ/KbaZ family. KbaZ subfamily.
Protein: AT2L1_MOUSE
Sequence: MCELYSKQDTLALRERHIGPSCKIFFAADPIKIMRAQGQYMFDEKGERYLDCINNVAHVGHCHPEVVKAAAKQMELLNTNSRFLHDNIIEFAKRLTATLPQELSVCYFTNSGSEANDLALRLARQFRGHQDVITLDHAYHGHLSSLIEISPYKFQKGKDVKRETVHVAPAPDTYRGKYREDHEDPSTAYADEVKKIIEEAHSSGRKIAAFIAESMQSCGGQIIPPAGYFQKVAEHIHKAGGVFIADEVQVGFGRVGRYFWSFQMYGEDFVPDIVTMGKPMGNGHPISCVVTTKEIAEAFSSSGMEYFNTYGGNPVSCAVGLAVLDVIEKENLQGNAVRVGTYLMELLSEQKAKHPLIGDIRGVGLFIGIDLVKDREKRTPATAEAQHIIYEMKGKGVLLSADGPHRNVLKIKPPMCFTEDDAKFLVDHLDGILTVLEEAMDSKSGTVFSENTAYRTKMPKEIQVELPNLSATEAREIPRGKRNGVCSDQQALLSKRLKT
What is the function of this protein?
Catalyzes the pyridoxal-phosphate-dependent breakdown of phosphoethanolamine, converting it to ammonia, inorganic phosphate and acetaldehyde.
What are the official names of this protein?
Ethanolamine-phosphate phospho-lyase, Alanine--glyoxylate aminotransferase 2-like 1.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: HCST_MOUSE
Sequence: MDPPGYLLFLLLLPVAASQTSAGSCSGCGTLSLPLLAGLVAADAVMSLLIVGVVFVCMRPHGRPAQEDGRVYINMPGRG
What is the function of this protein?
Transmembrane adapter protein which associates with KLRK1 to form an activation receptor KLRK1-HCST in lymphoid and myeloid cells; this receptor plays a major role in triggering cytotoxicity against target cells expressing cell surface ligands such as MHC class I chain-related MICA and MICB, and UL16-binding proteins (ULBPs); these ligands are up-regulated by stress conditions and pathological state such as viral infection and tumor transformation.  Functions as docking site for PI3-kinase PIK3R1 and GRB2.  Interaction of ULBPs with KLRK1-HCST triggers calcium mobilization and activation of the PIK3R1, MAP2K/ERK, and JAK2/STAT5 signaling pathways.  Both PIK3R1 and GRB2 are required for full KLRK1-HCST-mediated activation and ultimate killing of target cells.  In NK cells, KLRK1-HCST signaling directly induces cytotoxicity and enhances cytokine production initiated via DAP12/TYROBP-associated receptors.  In T-cells, it provides primarily costimulation for TCR-induced signals.  KLRK1-HCST receptor plays a role in immune surveillance against tumors and is required for cytolysis of tumors cells; indeed, melanoma cells that do not express KLRK1 ligands escape from immune surveillance mediated by NK cells.
What are the official names of this protein?
Hematopoietic cell signal transducer, DNAX-activation protein 10, Membrane protein DAP10, Transmembrane adapter protein KAP10.
What is the protein family that this protein belongs to?
Belongs to the DAP10 family.
What are the subcellular locations of this protein?
Membrane; Single- pass type I membrane protein.
Protein: Y1408_SULIA
Sequence: MSMPYDNEAKIKQAVILLQKIVNDTSVPRNIRRAATDAIRNLQDLGLSPAVRAANAIGILEDISQDPNMPTHARISIWNVVSILETVKD
What are the official names of this protein?
UPF0147 protein M1627_1408.
What is the protein family that this protein belongs to?
Belongs to the UPF0147 family.
Protein: NCAP_EAVBU
Sequence: MASRRSRPQAASFRNGRRRQPTSYNDLLRMFGQMRVRKPPAQPTQAIIAEPGDLRHDLNQQERATLSSNVQRFFMIGHGSLTADAGGLTYTVSWVPTKQIQRKVAPPAGP
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the arteriviridae nucleocapsid family.
What are the subcellular locations of this protein?
Virion.
Protein: NUOC_METPP
Sequence: MDHKIDLLQPALEAALAGKIQALVRDRGELTLTVTAADYLAVCTTLRDHAELKLEQLIDLCGLDYSSYKDGAGSPYTEGPRYCVVLHLLSVSKNWRLRLKVFCADDGLPVVPSVNEIWAAANWFEREAFDLYGIVFEGHADLRRILTDYGFIGHPFRKDFPTTGHVEMRYDAEQRRVIYQPVTIEPREITPRIIREDNYGGLH
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: WNT5B_DANRE
Sequence: MDVRMNQGHLLLAVTLIVCNSQLLVVANSWWSLAMNPIQRPEMYIIGAQPLCSQLTGLSQGQRKLCQLYQDHMVYIGEGAKTGIKECQYQFRQRRWNCSTVDNTSVFGRVMHIGSRETAFTYAVSAAGVVNAVSRACREGELSTCGCSRAARPRDLPRDWLWGGCGDNVNYGYRFAREFVDAREREKNYPRGSVEHARTLMNLQNNEAGRMAVYNLANVACKCHGVSGSCSLKTCWLQLADFRRVGEFLKEKYDSAAAMRINRRGKLELVNNRFNPPTGEDLVYIDPSPDYCLRNETTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDQFKTYKHERCHCKFHWCCYVKCKRCTSLVDQFVCK
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Can activate or inhibit canonical Wnt signaling, depending on receptor context.  Required during embryogenesis for extension of the primary anterior-posterior axis.  Regulates convergent extension movements and hypaxial myogenesis during gastrulation via activation of non-canonical Wnt signaling (PubMed:22406073).
What are the official names of this protein?
Protein Wnt-5b.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Secreted.
Protein: DNAJ_MESFL
Sequence: MAKRDYYEVLGVSKTSTEQEIKSAYRKLAKKYHPDMNKESGAEEKFKEVNEAASVLLDADKKAKYDQFGHAAFDGSSGFGGSGFGGFEDFFSNMGGGMDFGDIFSDLFGGGRSGRSSRRGPSKGQDIGLEATLTFKELVFGVNKKTILNLVKTCTKCDGVGAENPSDVHICTKCNGAGQIIVNKQMGPFQVQNQVTCDKCNGVGKEFKSKCKNCHGKGVESKREEVEIPLPKGLWPGQQFVMRGKGHASLEGGIPGDLYITIGIVKSDVFELIPNSNDLIMNYNISYLDAILGNEVIIKTLDGPVRLKIPKGVYSGQLIKVHDKGLYKNQTSDKRGDLLIKISISIPTSVSKEEKKILKELEQLSNFEPKNIID
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_CYAP4
Sequence: MKIVFWGTPSFAVPSLERLLREPDCEVLGVVTQPDKRRGRGNQLQPEAVKKVALAHNLPLWQPQRVKKDAATLADLRSLAADFFVVVAYGQILSPEILAMPRLGCINNHASLLPRYRGAAPIQWSLYNGETETGITTMLMDAGMDTGAMLLQRTLVVGLLENAEQVSQRLAELGADLVVETLRQQVVGQLQPIPQDNSQATYAPLIKKEDYGLDWHKSAIALQNQIRGFYPDCQTSLRGQPLKVSATLPLGSAYWSALPPEFQALAPQWTDERFAENHPPGSVIGLAKNLGPIIQTGAGGLLLLQVQPAGKRIQSGWDFVNGARLQIGEQLGLT
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: RIMM_GEOSL
Sequence: MRQDDLKLLGKIVTTHGIRGQLKVASFSGEFDTILSLETVVLKGKDGRMETFPVARATVHHDRVLLSLTPFTNINEVLHLISAVSYAHRDQFPPLEEGEYYWCDLIGLQVVTAAGTVIGRLDSILPTESHDVYVVRGADREYLIPAVEDVVVQVDLEAGTMTVSPPEGLLDL
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE_SHEPA
Sequence: MTVKTRFAPSPTGFLHVGGARTALYSWLYARANQGEFVLRIEDTDLERSTPEACAAILEGMEWLNLNWDEGPYYQTKRFDRYNEIIAQMLEQGTAYKCYCSRERIETMREEQAAKGEQQKYDGCCRDKAPRDTDEPFVVRFKNPTEGSVVFDDHVRGRIEFANSTLDDLIIARTEGTPTYNFCVVVDDWDMGITCVVRGEDHINNTPRQINILKALGAPVPEYAHVSMILGDDGAKLSKRHGAVGVMQYRDDGYLPEALLNYLVRLGWSHGDQEVFSIDEMKQFFNLDDINKAASAFNTDKLIWLNQHYIKESDPEYVASHLEWHMADQNIDTSNGPKLSEVVSALSERAKTLKELAASSRYFFEDFAEFDETAAKKHLRGVALEPLTLFQTKLAGLNDWTLEAIHQAIEDTATELEVGMGKVGMPLRVAVTGAGMSPAVDLTIFLVGKARTEQRISKAIEFVANRINS
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_THET2
Sequence: MRFLTAGESHGPELLAIIEGLPAGLPLSEEDINPWLEKRQKGYGRGRRMVIERDRVEFRAGVRGGRTTGAPVALAIKNADFKNWAEIMDPAPGNWPRKRALTAARPGHADLAGGMKYGHKDLRDVLERASARETAMRVAVGAVALKLLSLLGVEGVGYVPGMAGVWAKVPFSWDLVPRIEESPLRMTDPEAEAEAIRRIDQAKAEGDTLGGIIEARFRGLVPGLGSHVHWDRKLDGRLAQMALSIPAVKGVEIGPAFENAMKRGSEVHDAIYWSPERGFYRETNRAGGLEGGMTTGEELVVRAALKPIATLMKPLPTVDVVTHEPKDAARERSDTTAVPAASVILCALSAIVLAQAYLEKFGGDTMEEIQERVERYRERVRAY
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: SC61B_SCHPO
Sequence: MSSTKASGSVKNSAASAPGGPKSQIRRRAAVEKNTKESNSGPAGARAAGAPGSTPTLLKLYTDEASGFKVDPVVVMVLSVGFIASVFLLHIVARILKKFASE
What is the function of this protein?
Necessary for protein translocation in the endoplasmic reticulum.
What are the official names of this protein?
Protein transport protein sec61 subunit beta.
What is the protein family that this protein belongs to?
Belongs to the SEC61-beta family.