PharMolix/UniProtQA huggingface dataset:
Protein: C9MT_CANAL
Sequence: MLDDVAFIKTPAAKKQPPASNECGVWTTDSPAIHNAPLPADGPGSTSFSNTILFSILALVPGYITYKLGLGFKTWVFFFLILAIPILMAYWSIMSTFSPRINEKVKYPNRPISYYLEFHTPELKAKYETSNGGKGSKIPIETFQELYFDGKVSFKGDCLDVLEYKHDWASFRFTLGLFRFFLLGMIPEVIFHSQSQDEEQVRDHYDRGDDFYTWFLGPRMIYTSGVISDITREETLEELQDNKLTVMADKIDLKKGDHVLDIGCGWGTWTTFASSKYGANVTGITLGRNQTKWGNTLLKEYGIPSDQSRIVCCDYRDAPKSSKPSGKYDKITSVEMAEHVGIRRLTAYLEQCRDALEDDGLLFLQYSGLRKNWQYEDLEWGLFMNKYIFPGADASTPLSFFASCMESVGFEIVSVDNIGVHYSATLWRWYRNWIGNKDKVVNKYGVKWYRIWEFFLGSSVVASRNGTATCYQFICRKNINSYRRIDYVPQQKGLQGPVQEGTKWAKEFTNFYD
What is the function of this protein?
Catalyzes methylation of the sphingoid base component of glucosylceramides (GluCers) at the C9-position.  Sphingolipid C9-methylation requires 4,8-desaturated ceramides as substrates.  Glucosylceramides play important roles in growth, differentiation and pathogenicity.  The methyl group at the C9-position distinguishes fungal glucosylceramides from those of plants and animals, and may thus play a role in host-pathogen interactions enabling the host to recognize the fungal attack and initiate specific defense responses.  Not necessary for vegetative growth at low temperatures, but plays a role in hyphal formation on solid medium.
What are the official names of this protein?
Sphingolipid C9-methyltransferase, C-9-MT, Cyclopropane fatty acyl phospholipid synthase homolog 1, Methyltransferase for sphingolipid 1.
What is the protein family that this protein belongs to?
Belongs to the CFA/CMAS family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: SYC_SHESM
Sequence: MPMLKIYNSITRQKQEFKPITPGKVGMYVCGVTVYDLCHIGHGRTFVSFDMIVRYLRYAGYEVNFQRNITDIDDKIIKRANENQEDCNTLTDRLIGEMHKDFDALNMIRPDFEPRATLHITEIIDMVERLLARGHAYVAADGDVLFSVASFPEYGRLSGQNLEQLQAGARVEVDDNKQNPMDFVLWKMSKPGEPTWESPWGPGRPGWHIECSAMNSKHLGLHFDIHGGGSDLQFPHHENEIAQSCCAHDTPYVNYWMHTGMVMVDREKMSKSLGNFFTIRDVLGHYDPETVRYFLLSGHYRSQINYSEENLKQARAALERLYTAIKDVDLTVAPAPAEEFVAKFKAAMDDDFNTPEAYSVLFDMVREINRLKTTDMAQASAMAVAMKQLADVLGLLHQAPDAFFKGEGSDDEVAEIEALIVERNRARVEKDWPAADVARNRLNELGVVLEDGPSGTTWRKK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLRG1_RAT
Sequence: MVEEVQKHSVHTLVFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPTSKENLKEKGPQNAPDSYPHKQYPANQGQDVEYLVTGTHPYPPGPGVALTADTKIQRMPSESAAQSLAVALPSQTRVDANRTAPAGSEYRHPGASDRSQPTAMNSMIMETSNTKNSALMAKKAPTMPKPQWHPPWKLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPLHYTFASGSPDNIKQWKFPDGGFIQNLSGHNAIINTLAVNTDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDRSESRLLTAEADKTIKVYREDETATEETHPVSWKPEIIKRKRF
What is the function of this protein?
Involved in pre-mRNA splicing as component of the spliceosome.  Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing.  As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (By similarity).
What are the official names of this protein?
Pleiotropic regulator 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PRL1/PRL2 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle.
Protein: LACS9_ARATH
Sequence: MIPYAAGVIVPLALTFLVQKSKKEKKRGVVVDVGGEPGYAIRNHRFTEPVSSHWEHISTLPELFEISCNAHSDRVFLGTRKLISREIETSEDGKTFEKLHLGDYEWLTFGKTLEAVCDFASGLVQIGHKTEERVAIFADTREEWFISLQGCFRRNVTVVTIYSSLGEEALCHSLNETEVTTVICGSKELKKLMDISQQLETVKRVICMDDEFPSDVNSNWMATSFTDVQKLGRENPVDPNFPLSADVAVIMYTSGSTGLPKGVMMTHGNVLATVSAVMTIVPDLGKRDIYMAYLPLAHILELAAESVMATIGSAIGYGSPLTLTDTSNKIKKGTKGDVTALKPTIMTAVPAILDRVRDGVRKKVDAKGGLSKKLFDFAYARRLSAINGSWFGAWGLEKLLWDVLVFRKIRAVLGGQIRYLLSGGAPLSGDTQRFINICVGAPIGQGYGLTETCAGGTFSEFEDTSVGRVGAPLPCSFVKLVDWAEGGYLTSDKPMPRGEIVIGGSNITLGYFKNEEKTKEVYKVDEKGMRWFYTGDIGRFHPDGCLEIIDRKKDIVKLQHGEYVSLGKVEAALSISPYVENIMVHADSFYSYCVALVVASQHTVEGWASKQGIDFANFEELCTKEQAVKEVYASLVKAAKQSRLEKFEIPAKIKLLASPWTPESGLVTAALKLKRDVIRREFSEDLTKLYA
What is the function of this protein?
Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation.  Preferentially uses palmitate, palmitoleate, oleate and linoleate.
What are the official names of this protein?
Long chain acyl-CoA synthetase 9, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Plastid, chloroplast envelope.
Protein: MDH_BDEBA
Sequence: MKAPVRVAVTGAAGQIGYALLFRIASGAMLGADQPVILQLLEIPDEKAQKALKGVMMELEDCAFPLLHSMIATGDPAVAFKDADVALLVGARPRGPGMERKDLLTANGQIFTVQGEAIGKYANPNVKVLVVGNPANTNAYIAMKSAMKHGRVKAKNFTAMLRLDHNRALSQLATKTGKPVASFKKVAVWGNHSPTMYPDVRFATADGAKVPELLKLGTAEGDAWNKDTFIPTVGKRGAAIIEARGLSSAASAASAAVDHIRDWWLGTNGEWVTMGIPSDGSYDIPEGIMYGFPVTCKNGEYEIVKGLEIDAFSREKMNNTLKELNEEKDAVASML
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: DAPB_CYAP4
Sequence: MTNQGAIPVIVNGAAGKMGREVVKAVAQAADLTLFGAVDRNPSLQGQDIGEVVGIGPLEVPLLADLQSLLVAAAQEPQAGVMVDFTHPNSVYDNVRMAIAYGVRPVVGTTGLSPEQIRDLATFADKASMGCLIIPNFSIGMVLLQQAAIQASQYFDHVEIIELHHNQKADAPSGTALQTAQLLAELGKTYNPPAVKETEHLAGARGSLAEEGIRIHSVRLPGLIAHQEVIFGAPGQVYTLRHDTSDRSCYMPGVLLAIRKVMNLETVVYGLEKIL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FRDB_MYCTU
Sequence: MMDRIVMEVSRYRPEIESAPTFQAYEVPLTREWAVLDGLTYIKDHLDGTLSFRWSCRMGICGSSGMTINGDPKLACATFLADYLPGPVRVEPMRNFPVIRDLVVDISDFMAKLPSVKPWLVRHDEPPVEDGEYRQTPAELDAFKQFSMCINCMLCYSACPVYALDPDFLGPAAIALGQRYNLDSRDQGAADRRDVLAAADGAWACTLVGECSTACPKGVDPAGAIQRYKLTAATHALKKLLFPWGGG
What are the official names of this protein?
Fumarate reductase iron-sulfur subunit, Quinol-fumarate reductase iron-sulfur subunit, QFR iron-sulfur subunit.
What is the protein family that this protein belongs to?
Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NDK_DEHMC
Sequence: MERTLLLVKPDGVNRGLSGEILGRMEKLGLKLIGLRMLQMDAVLADKHYAPHRARPFFKDLVTYITSGPITAAVFEGENAVEKMRKAMGATDPAKSEKGTVRGDLGINIEQNTVHGSDSAENAKHEISLFFSESELVNYDRR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCDH8_HUMAN
Sequence: MSPVRRWGSPCLFPLQLFSLCWVLSVAQSKTVRYSTFEEDAPGTVIGTLAEDLHMKVSGDTSFRLMKQFNSSLLRVREGDGQLTVGDAGLDRERLCGQAPQCVLAFDVVSFSQEQFRLVHVEVEVRDVNDHAPRFPRAQIPVEVSEGAAVGTRIPLEVPVDEDVGANGLQTVRLAEPHSPFRVELQTRADGAQCADLVLLQELDRESQAAYSLELVAQDGGRPPRSATAALSVRVLDANDHSPAFPQGAVAEVELAEDAPVGSLLLDLDAADPDEGPNGDVVFAFGARTPPEARRLFRLDPRSGRLTLAGPVDYERQDTYELDVRAQDRGPGPRAATCKVIVRIRDVNDNAPDIAITPLAAPGAPATSPFAAAAAAAALGGADASSPAGAGTPEAGATSLVPEGAARESLVALVSTSDRDSGANGQVRCALYGHEHFRLQPAYAGSYLVVTAASLDRERIAEYNLTLVAEDRGAPPLRTVRPYTVRVGDENDNAPLFTRPVYEVSVRENNPPGAYLATVAARDRDLGRNGQVTYRLLEAEVGRAGGAVSTYVSVDPATGAIYALRSFDYETLRQLDVRIQASDGGSPQLSSSALVQVRVLDQNDHAPVLVHPAPANGSLEVAVPGRTAKDTVVARVQARDADEGANGELAFELQQQEPREAFAIGRRTGEILLTGDLSQEPPGRVFRALLVISDGGRPPLTTTATVSFVVTAGGGRGPAAPASAGSPERSRPPGSRLGVSGSVLQWDTPLIVIIVLAGSCTLLLAAIIAIATTCNRRKKEVRKGGALREERPGAAGGGASAPGSPEEAARGAGPRPNMFDVLTFPGTGKAPFGSPAADAPPPAVAAAEVPGSEGGSATGESACHFEGQQRLRGAHAEPYGASPGFGKEPAPPVAVWKGHSFNTISGREAEKFSGKDSGKGDSDFNDSDSDISGDALKKDLINHMQSGLWACTAECKILGHSDRCWSPSCSGPNAHPSPHPPAQMSTFCKSTSLPRDPLRRDNYYQAQLPKTVGLQSVYEKVLHRDYDRTVTLLSPPRPGRLPDLQEIGVPLYQSPPGRYLSPKKGANENV
What is the function of this protein?
Calcium-dependent cell-adhesion protein (By similarity).  May play a role in activity-induced synaptic reorganization underlying long term memory (By similarity).  Could be involved in CDH2 internalization through TAOK2/p38 MAPK pathway.  In hippocampal neurons, may play a role in the down-regulation of dendritic spines, maybe through its action on CDH2 endocytosis (By similarity).
What are the official names of this protein?
Protocadherin-8, Arcadlin.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell projection, dendrite. Presynaptic cell membrane. Postsynaptic cell membrane. Note=Also expressed in neuronal cell bodies. Localized to excitatory, but not with inhibitory, synapses.
Protein: METK_HISS2
Sequence: MSSYLFTSESVSEGHPDKIADQISDAVLDEILRQDPKARVACETYVKTGMALVGGEITTSAWVDIENLTRQVICDIGYKHSDIGFDGHSCAVLNAIGKQSSDINQGVDRESPLDQGAGDQGIMFGYATNETDVLMPAAITYAHRLMERQAQVRKKGILDWLRPDAKSQVTLKYEDNRIVGIDAVVLSTQHSDNVDQKTVHEGVMEEIIKPILPAEWLSKETKYFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGAARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQLSYAIGVAEPTSIMVETFGTGKVANELLVGLIREFFDLRPYGLIKMLDLIQPIYRQTAAYGHFGRAQFPWEKVDRAEELRAAASLK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURD_HAHCH
Sequence: MSILARDRNIAVIGLGKTGLSCADYLTRRGYGFCVMDTRENPSGLAELNAINPDVPVVTGKLDQDMLARAAEIWLSPGVPLSHPDLQAVKGQVKICGDVDVFSREANAPILAITGSNGKSTVTTLVGEMAKACGVNVAVGGNLGTPVLDLLADEVELYVVELSSFQLETTDRLGALAATVLNLSEDHMDRYADMMAYHLAKLRVFYGCRRQVLNRDDALAQPPLSREAEITWFTLKTPEPGQYGVLEEKDGAWLAYGAEKLLPVEQMRIRGKHNWSNALAALALADAAGLEREPCLQALREFTGLTHRCEWVADKDGVAYINDSKATNVGATQAALAGLGPVTSGGIVLICGGQGKGQDFTPLAPAVKEWVSTLIIIGEDGPKLKEALAGGVMALSAETMEEAVKLAAEKSSPGDLVLLSPACASFDMFKNYEDRGDQFKQWVRAL
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCHD_PSEAE
Sequence: MTSSPVTPSAVDDAPDWPAAFVRRYLDAGHWQDQSFAEALATSAARHPRRIALCDDDQRLSYADLLQRCRRLAAGLRQAGLAHGDTVVLHLPNGIAFVETCFALFQLGVRPVLALPAHRQHEISGFCRFAEAKAYIGAERIDGFDPRPMARELLASGACRMALIHGEAEAPLQALAPLYQADALEDCAARAEDIACFQLSGGTTGTPKLIPRRHREYLYNVRASAEVCGFDEHTVYLTGLPMAHNFTLCCPGVIGTLLASGRVVVSQRADPEHCFALIARERVTHTALVPPLAMLWLDAQESRRADLSSLRLLQVGGSRLGSSAAQRVEPVLGCQLQQVLGMAEGLICYTRLDDPPERVLHTQGRPLSPDDEVRVVDAEGREVGPGEVGELTVRGPYTIRGYYRLPEHNAKAFSADGFYRTGDRVSRDKDGYLVVEGRDKDQINRGGEKIAAEEVENLLIAHPQVHDATVVAMPDSLLGERTCAFVIPRQPAPSALKLKQYLHACGLAAFKVPDRIELVPAFPQTGIGKISKKDLRERLRRELEARA
What is the function of this protein?
Involved in the biosynthesis of the siderophore pyochelin (PubMed:8982005).  Specifically adenylates salicylate and loads it onto the holo form of PchE via a thioester linkage to the phosphopanthetheine moiety (By similarity).  Is also involved in the synthesis of the antifungal antibiotic dihydroaeruginoic acid (Dha or hydroxyphenyl-thiazolinyl-carboxylate), a precursor of pyochelin (PubMed:8982005).
What are the official names of this protein?
Pyochelin synthase PchD, Nonribosomal peptide synthase PchD, Salicylate--[aryl-carrier protein] ligase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: MSBA_SYNAS
Sequence: MAGNRGCKPRRFEGNQRMDIFKRLLKLARPHAPRFAVAMVCMLIAGALTSSLAFLVKPALDDIFLDRNAEMLKWIPLAIILIYLVKGGCSYFQAILMSFIGQRIVADLRNRLYEQIQKQSLSFFSKNPTGVLMSRITNDVNSIQGTVSDAVTSLMKDSFTLICLVFVIFYRDWQLAIIAMIVFPLTIYPIAKFGQKMRSVATRTQVTMGSLTTLLQETISGTRIVRAFCMEAHENQRFARENEKLMHLALKSVSINALSSPFMEFLGGIGIAAIIFYGGYQVIKGSSTPGTFFSFLTALIMLYEPVKRLTNVNNTIQQGIAGAQRVFSIIDLVPDIVDRDEAVELPRISEKIEIRNISFAYDDTPVLRNINLTIRAGEVVAFVGMSGGGKTTLVNLIPRFYDVTAGQILIDGHDIRDVSLISLRRQIGIVTQQTILFNDTVRNNIAYGSQGCSEKEIIEAARAANAHDFIVNLPEGYDTVIGELGTKLSGGERQRISIARALLKNAPILILDEATSSLDTEAEMEVQEALERLMKGRTTLVIAHRLSTIRNADRIVVLVKGEIVEEGAHETLLARRGEYYKLHQLQFKEDKVGEEVGRNDS
What is the function of this protein?
Involved in lipopolysaccharide (LPS) biosynthesis.  Translocates lipid A-core from the inner to the outer leaflet of the inner membrane.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
What are the official names of this protein?
ATP-dependent lipid A-core flippase, Lipid A export ATP-binding/permease protein MsbA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SRP72_HUMAN
Sequence: MASGGSGGVSVPALWSEVNRYGQNGDFTRALKTVNKILQINKDDVTALHCKVVCLIQNGSFKEALNVINTHTKVLANNSLSFEKAYCEYRLNRIENALKTIESANQQTDKLKELYGQVLYRLERYDECLAVYRDLVRNSQDDYDEERKTNLSAVVAAQSNWEKVVPENLGLQEGTHELCYNTACALIGQGQLNQAMKILQKAEDLCRRSLSEDTDGTEEDPQAELAIIHGQMAYILQLQGRTEEALQLYNQIIKLKPTDVGLLAVIANNIITINKDQNVFDSKKKVKLTNAEGVEFKLSKKQLQAIEFNKALLAMYTNQAEQCRKISASLQSQSPEHLLPVLIQAAQLCREKQHTKAIELLQEFSDQHPENAAEIKLTMAQLKISQGNISKACLILRSIEELKHKPGMVSALVTMYSHEEDIDSAIEVFTQAIQWYQNHQPKSPAHLSLIREAANFKLKYGRKKEAISDLQQLWKQNPKDIHTLAQLISAYSLVDPEKAKALSKHLPSSDSMSLKVDVEALENSAGATYIRKKGGKVTGDSQPKEQGQGDLKKKKKKKKGKLPKNYDPKVTPDPERWLPMRERSYYRGRKKGKKKDQIGKGTQGATAGASSELDASKTVSSPPTSPRPGSAATVSASTSNIIPPRHQKPAGAPATKKKQQQKKKKGGKGGW
What is the function of this protein?
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (PubMed:34020957).  The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER (PubMed:34020957).  The SRP complex targets the ribosome-nascent chain complex to the SRP receptor (SR), which is anchored in the ER, where SR compaction and GTPase rearrangement drive cotranslational protein translocation into the ER (PubMed:34020957).  Binds the signal recognition particle RNA (7SL RNA) in presence of SRP68 (PubMed:27899666, PubMed:21073748).  Can bind 7SL RNA with low affinity (PubMed:27899666, PubMed:21073748).  The SRP complex possibly participates in the elongation arrest function (By similarity).
What are the official names of this protein?
Signal recognition particle subunit SRP72, SRP72, Signal recognition particle 72 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the SRP72 family.
Protein: DABC_PSEMU
Sequence: MTVAINNETVVLTPNEDDVQVNKGKTLETSFPPLKGDDLKWFPRSSLPAEIPAIDIGKVSTKEELEQFLVDIRKSGLFYIVNHGVPEEVSINVYNAFREFISTTTEEERMKYYTDTHFQNGGYVPFQGSSIRGGNLGKPQKDHVVKYFWRGPEVINRTPNEKFTEAHNMHHTETFKVAEKVIRTIFKALKLRFPDFDPMEFENTINSKKMFFTNRIYPQAEPSDEEEITHRLVPHLDTSFITLANQVPADNGFQGLFVETGDGKKVKVPGIRNSYLVFIGQSLSYLTKNYLPSALHGVDKPPSDLFEGSERSSLITFYEPAEIIIPSKNINPNPEETSESCPFFYDIGLTVNDPEGTTWDFVKNKFITGYYAD
What is the function of this protein?
Iron/ascorbate-dependent oxidoreductase: part of the gene cluster that mediates the biosynthesis of domoic acid (DA) and derivatives, natural products with neurochemical activity acting as ionotropic glutamate receptor (iGluR) agonists, thus being neurotoxins causing amnesic shellfish poisoning (ASP) (PubMed:30262498).  Catalyzes the conversion of 7'-N-carboxy-L-geranyl-L-glutamic acid (cNGG) to isodomoic acid-A (PubMed:30262498).  Mediates also the conversion of N-geranyl-L-glutamic acid (L-NGG) to dainic acid A (PubMed:30262498).
What are the official names of this protein?
Alpha-ketoglutarate dependent kainoid synthase, Alpha-KG dependent kainoid synthase, Domoic acid biosynthesis cluster protein C, PmDabC.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: RS19_ALCBS
Sequence: MPRSLKKGPFVDHHLLGKVEDAVEAGSRKPIKTWSRRSMIIPEMVGLTIAVYNGKQHVPVMVSEHMVGHKLGEFALTRNYRGHAVDKKAKR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: RR19_CALFG
Sequence: MTRSLKKNPFVANHLLAKIEKLNMREEKETIVTWSRASTIIPTMIGHTIAIHNGKEHLPIFITDRMVGHKLGEFAPTLTFRGHARTDTRSRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DPOL_HBVH3
Sequence: MPLSYQHFRRLLLLDNEAGPLEEELPRLADEDLNHRVAEDLNLQLPNVSIPWTHKVGNFTGLYSSTVPVFNPDWLTPSFPDIHLHQDLIQKCEQFVGPLTKNEVRRLKLIMPARFYPKVTKYFPLDKGIKPYYPEHVVNHYFKTRHYLHTLWKAGILYKRESTHSASFCGSPYSWEQELQHGSTSLNGEKGHGTESFCAQSSGILSRPPVGSTIQSKFQQSRLGLQHKQGQLANGKQGRSGRLWSRVHTPTRWPSGVEPSGTGHSDNLATRSTSRFHQSEVRKETNPSLSTSKGHTSTGHAVELNTVPPSTVGSESKGSVSSCWWLQFRNTEPCSDYCLSHIINLLEDWGPCYEHGEHHIRTPRTPSRVTGGVFLVDKNPHNTTESRLVVDFSQFSRGTTRVSWPKFAVPNLQSLTNLLSSNLSWLSLDVSAAFYHLPLHPAAMPHLLVGSSGLSRYVARVSSTSRIYNHQHGSLQNLHHSCSRNLYVSLLLLYQTFGRKLHLYSHPIILGFRKIPMGVGLSPFLLAQFTSAICSVVRRAFPHCLAFSYMDDLVLGAKSVQHLESLYTAVTNFLLSVGIHLNTAKTKWWGYSLHFMGYIIGSWGTLPQEHIVQKIKDCFRKLPVNRPIDWKVCQRIVGLLGFAAPFTQCGYPALMPLYACITAKQAFVFSPTYKAFLCKQYMNLYPVARQRPGLCQVFADATPTGWGLAIGHQRMRGTFVAPLPIHTAELLAACFARSRSGADIIGTDNSVVLSRKYTSFPWLLGCAANWILRGTSFVYVPSALNPADDPSRGRLGLCRPLLRLPFRPTTGRTSLYADSPPVPSHLPARVHFASPLHVAWRPP
What is the function of this protein?
Multifunctional enzyme that converts the viral RNA genome into dsDNA in viral cytoplasmic capsids.  This enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes in a partially processive 3'- to 5'-endonucleasic mode.  Neo-synthesized pregenomic RNA (pgRNA) are encapsidated together with the P protein, and reverse-transcribed inside the nucleocapsid.  Initiation of reverse-transcription occurs first by binding the epsilon loop on the pgRNA genome, and is initiated by protein priming, thereby the 5'-end of (-)DNA is covalently linked to P protein.  Partial (+)DNA is synthesized from the (-)DNA template and generates the relaxed circular DNA (RC-DNA) genome.  After budding and infection, the RC-DNA migrates in the nucleus, and is converted into a plasmid-like covalently closed circular DNA (cccDNA).  The activity of P protein does not seem to be necessary for cccDNA generation, and is presumably released from (+)DNA by host nuclear DNA repair machinery.
What are the official names of this protein?
Protein P.
What is the protein family that this protein belongs to?
Belongs to the hepadnaviridae P protein family.
Protein: THCL_BACCR
Sequence: MSEIKKALNTLEIEDFDAIEMVDVDAMPENEALEIMGASCTTCVCTCSCCTT
What is the function of this protein?
Has bacteriocidal activity against Gram-positive bacteria, but not against Gram-negative bacteria.  Inhibits bacterial protein biosynthesis by acting on the elongation factor Tu (EF-Tu) (By similarity).
What are the official names of this protein?
Thiocillin, Antibiotic YM-266183, Antibiotic YM-266184, Micrococcin P1, Micrococcin P2, Thiocillin I, Thiocillin II, Thiocillin III, Thiocillin IV.
What is the protein family that this protein belongs to?
Belongs to the thiocillin family.
What are the subcellular locations of this protein?
Secreted.
Protein: KBP_DANRE
Sequence: MAANNSIEWRAVCEKFRLAQELSEIESKKDPENNPFRSKYKARDLLKEIHCSLKKIEIEEQGEAGDEADCESSQTADGEPEDGFEKTFTGDSAAGLRAARLAVLQYHLGVNHIETEELSAGELHLMVCMKLIDKCTTTRENVSLFIHVRNQLGILWAGRDEIEKAQGFLEIAETMYLVYMKEDGQPPLDLQDFFVPEGEELSQQEKIRRFEMAYTHTLYYLAQVYKNLQQYERAAQYCHSTLQRQLEYKQFAPLEWAINAATLSQYYITKTRYMEARHCLAAASVIANLAGEIPSEAAAKESEAESEKREELLQKRAEIARCWIKYCLNLLQDAKKLLEDNIGELDLDRQDELKRARRNEEEEKEKGRKSAILFGSSDTFDSICSLEEKVSSMLPLEFEEARSIFLVGQSYVTQAKEYFAMDGHVTDHIEILQDHSALFKVLAFFEEDLERRCKMHKRRVDMLEPICKDLNAQYYLLICRQLQFELAETYYEMMDLKLAVADKLDQPDVHTIKKFNHLCSSSMKYYQMFLDSTRSPEGKFPEKLEDDLLRPALVAKFRVARLHSKLISSNLATQMENLSLSLESYNFVVQYCEENPEAKNAVETELELSMEMVSLLPLKINRIRSTLASSK
What is the function of this protein?
Required for organization of axonal microtubules, and axonal outgrowth and maintenance during peripheral and central nervous system development.
What are the official names of this protein?
KIF-binding protein, KIF1-binding protein.
What is the protein family that this protein belongs to?
Belongs to the KIF-binding protein family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RL10_PROM3
Sequence: MGRTLESKQQIVEELKGLLGEAEMALVLDYQGLSIKEMSDLRTRLQASNGVCKVTKNTLMRHAINGNGAWSNLESLLTGTNAFVLIKGDVGGAVKAVQAFQKDTKKSETKGGLFEGKLLSQGEIKAIGDLPTKEVLMAQIAGSLNALATKVAVGINEVPSGLARALHQHAESGES
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.