PharMolix/UniProtQA huggingface dataset:
Protein: BAME3_ARATH
Sequence: MADKIFTFFLILSSISPLLCSSLISPLNLSLIRQANVLISLKQSFDSYDPSLDSWNIPNFNSLCSWTGVSCDNLNQSITRLDLSNLNISGTISPEISRLSPSLVFLDISSNSFSGELPKEIYELSGLEVLNISSNVFEGELETRGFSQMTQLVTLDAYDNSFNGSLPLSLTTLTRLEHLDLGGNYFDGEIPRSYGSFLSLKFLSLSGNDLRGRIPNELANITTLVQLYLGYYNDYRGGIPADFGRLINLVHLDLANCSLKGSIPAELGNLKNLEVLFLQTNELTGSVPRELGNMTSLKTLDLSNNFLEGEIPLELSGLQKLQLFNLFFNRLHGEIPEFVSELPDLQILKLWHNNFTGKIPSKLGSNGNLIEIDLSTNKLTGLIPESLCFGRRLKILILFNNFLFGPLPEDLGQCEPLWRFRLGQNFLTSKLPKGLIYLPNLSLLELQNNFLTGEIPEEEAGNAQFSSLTQINLSNNRLSGPIPGSIRNLRSLQILLLGANRLSGQIPGEIGSLKSLLKIDMSRNNFSGKFPPEFGDCMSLTYLDLSHNQISGQIPVQISQIRILNYLNVSWNSFNQSLPNELGYMKSLTSADFSHNNFSGSVPTSGQFSYFNNTSFLGNPFLCGFSSNPCNGSQNQSQSQLLNQNNARSRGEISAKFKLFFGLGLLGFFLVFVVLAVVKNRRMRKNNPNLWKLIGFQKLGFRSEHILECVKENHVIGKGGRGIVYKGVMPNGEEVAVKKLLTITKGSSHDNGLAAEIQTLGRIRHRNIVRLLAFCSNKDVNLLVYEYMPNGSLGEVLHGKAGVFLKWETRLQIALEAAKGLCYLHHDCSPLIIHRDVKSNNILLGPEFEAHVADFGLAKFMMQDNGASECMSSIAGSYGYIAPEYAYTLRIDEKSDVYSFGVVLLELITGRKPVDNFGEEGIDIVQWSKIQTNCNRQGVVKIIDQRLSNIPLAEAMELFFVAMLCVQEHSVERPTMREVVQMISQAKQPNTF
What is the function of this protein?
Necessary for male gametophyte development, as well as ovule specification and function (PubMed:16367950).  Required for the development of high-ordered vascular strands within the leaf and a correlated control of leaf shape, size and symmetry (PubMed:16367950).  LRR-rich receptor-like kinase (LRR-RLK) involved in the perception of CLE45 peptide ligand which mediates root growth inhibition by repressing protophloem differentiation; this mechanism requires CRN (PubMed:23569225, PubMed:28607033, PubMed:25049386).  BRX, BAM3, and CLE45 act together to regulate the transition of protophloem cells from proliferation to differentiation, thus impinging on postembryonic growth capacity of the root meristem (PubMed:23569225, PubMed:25049386).  Necessary for CLE45 peptide-triggered accumulation of MAKR5 in developing sieve elements (PubMed:27354416).
What are the official names of this protein?
Leucine-rich repeat receptor-like serine/threonine-protein kinase BAM3, Protein BARELY ANY MERISTEM 3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: ISPH_SULNB
Sequence: MKIQLASSYGFCFGVKRAIKIAEEHQGSKTYGPLIHNKDEINRLKEGFDIGLAEKLDDVTPEDSVVIRTHGIPKDELSQLKAQENPIIDATCPYVTTPQNIVANMSEKGYSIVIFGDKEHPEIKGVVSYAKDLRNAFIVKHEDELKGLPILSKVAVVAQTTRKPEDFLKIVNALILNHKEVRVFNTICNATFENQDAAAELAKDADVMVVIGGKHSSNTKQLHSICKSYCDDSYLIENEAELEPKWFEGKKLCGISAGASTPDWIVQNVIDKIEALK
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: NDOR1_YEAST
Sequence: MSSSKKIVILYGSETGNAHDFATILSHRLHRWHFSHTFCSIGDYDPQDILKCRYLFIICSTTGQGELPRNVNALKGERPVTFWSFLKRKNLPSNLLNHIQTAMLGLGDSSYPKFNYGIRKLHQRIVTQLGANELFDRLEADDQAMAGSNKGTGLGIESVYFEYEKKVLSFLLSKYPNRKVNGQIIKREELDPEVYLEPASYLQLSDEHANEKFTSTKVIFEGDESLKVGRVNINKRITSEGHFQDVRQFKFSNVDKIQENYEPGDTVTIYPCNTDEDVSRFLANQSHWLEIADKPLNFTSGVPNDLKDGGLVRPMTLRNLLKYHCDFMSIPRTSFFLKIWTFATDVTKMERGQEQLNDQREKLRQFATDQDMQDLYDYCNRPRRSILEVLEDFISVKLPWKYVLDYLPIIKPRYYSISSGPGDPNIELTVAIVKYKTILRKIRRGICTNYIARLQEGEQIRYKLQNNHIIKKEFLNKPMILVGPGVGLAPLLSVVKAEISKDIKLLFGCRYKDKDYIYKDMLEDWFRKGKIALHSSFSRDEENSPGVKYVQDYLWRLGEEITNLVVNKDAVFFLCGSSGKMPIQVRLTFIEMLKKWGNFSDEETAKKYLKEMEKSDRYIQETW
What is the function of this protein?
NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery (PubMed:20802492).  Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of DRE2, another key component of the CIA machinery (PubMed:20802492, PubMed:21902732).  In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins (PubMed:20802492).  Positively controls H(2)O(2)-induced cell death (PubMed:19194512).
What are the official names of this protein?
NADPH-dependent diflavin oxidoreductase 1, NADPH-dependent FMN and FAD-containing oxidoreductase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Note=Relocalizes to mitochondria after H(2)O(2) exposure.
Protein: CATR3_PARTE
Sequence: MARRGQQPPPQQQQAPPTQKNQAGKFNPAEFVKPGLTEEEVLEIKEAFDLFDTDGTQSIDPKELKAAMTSLGFEAKNQTIYQMISDLDTDGSGQIDFAEFLKLMTARISERDSKADIQKVFNLFDSERAGVITLKDLRKVAKELGETMDDSELQEMIDRADSDGDAQVTFEDFYNIMTKKTFA
What is the function of this protein?
Plays a fundamental role in microtubule organizing center structure and function.  Component of the infraciliary lattice (ICL) and the ciliary basal bodies.
What are the official names of this protein?
Caltractin ICL1c, Centrin-3.
What is the protein family that this protein belongs to?
Belongs to the centrin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=ICL, innermost fibrous network of the cortical cytoskeleton.
Protein: RL30_ECO45
Sequence: MAKTIKITQTRSAIGRLPKHKATLLGLGLRRIGHTVEREDTPAIRGMINAVSFMVKVEE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: DIC_MOUSE
Sequence: MAEARASRWYFGGLASCGAACCTHPLDLLKVHLQTQQEVKLRMTGMALQVVRTDGFLALYNGLSASLCRQMTYSLTRFAIYETMRDYMTKDSQGPLPFYNKVLLGGISGLTGGFVGTPADLVNVRMQNDMKLPPSQRRNYSHALDGLYRVAREESLRKLFSGATMASSRGALVTVGQLSCYDQAKQLVLSTGYLSDNIFTHFVSSFIAGGCATFLCQPLDVLKTRLMNSKGEYQGVFHCAMETAKLGPQAFFKGLFPAGIRLIPHTVLTFMFLEQLRKHFGIKVPTT
What is the function of this protein?
Catalyzes the electroneutral exchange or flux of physiologically important metabolites such as dicarboxylates (malonate, malate, succinate), inorganic sulfur-containing anions, and phosphate, across mitochondrial inner membrane (PubMed:33746082).  Plays an important role in gluconeogenesis, fatty acid metabolism, urea synthesis, and sulfur metabolism, particularly in liver, by supplying the substrates for the different metabolic processes (PubMed:33746082, PubMed:16027120, PubMed:30943427).  Regulates fatty acid release from adipocytes, and contributes to systemic insulin sensitivity (PubMed:33746082).
What are the official names of this protein?
Mitochondrial dicarboxylate carrier, DIC, Solute carrier family 25 member 10.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PPWD1_HUMAN
Sequence: MAAESGSDFQQRRRRRRDPEEPEKTELSERELAVAVAVSQENDEENEERWVGPLPVEATLAKKRKVLEFERVYLDNLPSASMYERSYMHRDVITHVVCTKTDFIITASHDGHVKFWKKIEEGIEFVKHFRSHLGVIESIAVSSEGALFCSVGDDKAMKVFDVVNFDMINMLKLGYFPGQCEWIYCPGDAISSVAASEKSTGKIFIYDGRGDNQPLHIFDKLHTSPLTQIRLNPVYKAVVSSDKSGMIEYWTGPPHEYKFPKNVNWEYKTDTDLYEFAKCKAYPTSVCFSPDGKKIATIGSDRKVRIFRFVTGKLMRVFDESLSMFTELQQMRQQLPDMEFGRRMAVERELEKVDAVRLINIVFDETGHFVLYGTMLGIKVINVETNRCVRILGKQENIRVMQLALFQGIAKKHRAATTIEMKASENPVLQNIQADPTIVCTSFKKNRFYMFTKREPEDTKSADSDRDVFNEKPSKEEVMAATQAEGPKRVSDSAIIHTSMGDIHTKLFPVECPKTVENFCVHSRNGYYNGHTFHRIIKGFMIQTGDPTGTGMGGESIWGGEFEDEFHSTLRHDRPYTLSMANAGSNTNGSQFFITVVPTPWLDNKHTVFGRVTKGMEVVQRISNVKVNPKTDKPYEDVSIINITVK
What is the function of this protein?
PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding (PubMed:20676357).  May be involved in pre-mRNA splicing (PubMed:11991638).
What are the official names of this protein?
Peptidylprolyl isomerase domain and WD repeat-containing protein 1, Spliceosome-associated cyclophilin.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIL1 subfamily.
Protein: RL18_RHILW
Sequence: MASRKEALARRANRVRRHLKSVANGRPRLSVHRSSKNIYAQVIDDVAGKTLAAASTLDKDLRGSLKTGADTAAAALVGKLVAERASKAGVTDVVFDRGAFIYHGRIKALADAAREGGLTF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: ACYP_GEOKA
Sequence: MKRVHVIVEGRVQGVGFRYFVQHEALKRQLTGWVKNNDDGTVEMEVQGNESALQLFLDTIEAGTMFAKVARMHIEPRDVRSDEKQFRIMYGSGF
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: EAMB_ECO57
Sequence: MTPTLLSAFWTYTLITAMTPGPNNILALSSATTHGFHQSTRVLAGMSLGFLIVMLLCAGISFSLAVIDPAAVHLLSWAGAAYIVWLAWKIATSPTKEDGLQTKPISFWASFALQFVNVKIILYGVTALSTFVLPQTQALSWIVGVSVLLAMIGTFGNVCWALAGHLFQRLFRQYGRQLNIVLALLLIYCAVRIFY
What is the function of this protein?
Exporter of O-acetylserine (OAS) and cysteine.
What are the official names of this protein?
Cysteine/O-acetylserine efflux protein.
What is the protein family that this protein belongs to?
Belongs to the Rht family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SSBA_BACSU
Sequence: MLNRVVLVGRLTKDPELRYTPNGAAVATFTLAVNRTFTNQSGEREADFINCVTWRRQAENVANFLKKGSLAGVDGRLQTRNYENQQGQRVFVTEVQAESVQFLEPKNGGGSGSGGYNEGNSGGGQYFGGGQNDNPFGGNQNNQRRNQGNSFNDDPFANDGKPIDISDDDLPF
What is the function of this protein?
Plays an important role in DNA replication, recombination and repair.  Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism (PubMed:21170359).  Has a 20-fold higher affinity for ssDNA than SsbB; SsbA and DprA activate the homologous DNA strand exchange function of RecA-ATP (PubMed:25138221).
What are the official names of this protein?
Single-stranded DNA-binding protein A, SSB A.
Protein: RECR_ECOLI
Sequence: MQTSPLLTQLMEALRCLPGVGPKSAQRMAFTLLQRDRSGGMRLAQALTRAMSEIGHCADCRTFTEQEVCNICSNPRRQENGQICVVESPADIYAIEQTGQFSGRYFVLMGHLSPLDGIGPDDIGLDRLEQRLAEEKITEVILATNPTVEGEATANYIAELCAQYDVEASRIAHGVPVGGELEMVDGTTLSHSLAGRHKIRF
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: O16G1_BACSU
Sequence: MSEWWKEAVVYQIYPRSFYDANGDGFGDLQGVIQKLDYIKNLGADVIWLSPVFDSPQDDNGYDISDYKNMYEKFGTNEDMFQLIDEVHKRGMKIVMDLVVNHTSDEHAWFAESRKSKDNPYRDYYLWKDPKPDGSEPNNWGSIFSGSAWTYDEGTGQYYLHYFSKKQPDLNWENEAVRREVYDVMRFWMDRGVDGWRMDVIGSISKYTDFPDYETDHSRSYIVGRYHSNGPRLHEFIQEMNREVLSHYDCMTVGEANGSDIEEAKKYTDASRQELNMIFTFEHMDIDKEQNSPNGKWQIKPFDLIALKKTMTRWQTGLMNVGWNTLYFENHDQPRVISRWGNDRKLRKECAKAFATVLHGMKGTPFIYQGEEIGMVNSDMPLEMYDDLEIKNAYRELVVENKTMSEKEFVKAVMIKGRDHARTPMQWDAGKHAGFTAGDPWIPVNSRYQDINVKESLEDQDSIFFYYQKLIQLRKQYKIMIYGDYQLLQENDPQVFSYLREYRGEKLLVVVNLSEEKALFEAPPELIHERWKVLISNYPQERADLKSISLKPYEAVMGISI
What is the function of this protein?
Hydrolyzes various disaccharides such as sucrose, maltose, and isomaltose with different efficiencies.  Also hydrolyzes longer maltodextrins from maltotriose up to maltohexaose, but not maltoheptaose, palatinose, isomaltotriose, or isomaltotetraose.
What are the official names of this protein?
Oligo-1,6-glucosidase 1, Dextrin 6-alpha-D-glucanohydrolase, Oligosaccharide alpha-1,6-glucosidase 1, Sucrase-isomaltase 1, Isomaltase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS_SACD2
Sequence: MNSTSTATPIANENHTPMMQQYLRIKAEHPNEIVFYRMGDFYELFFDDAKKAAKLLDVTLTARGKSNGEPIPMAGVPYHAAENYLAKLVRLGVSVAIVEQVGDPATTKGPVERKVMRIVTPGTVSDEALLDETRDNLLVAITLKDERYGISSLDMGSGRFTVFEVADEEALIGEIERLQPAELLAPELLTVPNIISLRAGYRRRPDWEFEYDTAQRLLTRHFGTQDLSGFGCEDFTAGISAAGCLFAYAQETQKTTLSHVAKLVLDNPETKVTLDAATRRNLELDTNLAGTEDNTLFSVLNTTTTAMGGRLLRRWLHSPLRDIYILNQRQSAIEALLDNYQFEPLRHTLKHISDLERILGRLALRSARPRDLSRLCASIAEFPAIQQHLNGIDSPLLKKLAKEIREFPDLVDLLSRALMENPPVVIREGGVIAEGFDEELDELRAISTNAGDYLIKLEEQERAKTGLSTLKVGYNRVHGYYIEISKSQASSAPTEYIRRQTLKNAERFITPELKTFEDKALSAKSRALAREKGLYDDLIETLNEQLRELQVAASGVAELDVLTTLAERSNLLNFCKPELYEGEGIFIEQGRHPVVEQVLDDPFVPNDLLLDTDQRMLIITGPNMGGKSTYMRQTALIVLLAQIGCYVPASACKLGLVDRIFTRIGSSDDLAGGRSTFMVEMTETANILNNATRNSLVLMDEIGRGTSTYDGLSLAWACVEHLANNLHAFTLFATHYFELTGLPKALAGVQNVHLDATEHNDSIVFLHKIQPGPASKSFGLQVAKLAGIPSNVIADAGGHLRRLEAQPTVDTPHQFPAPEPIALQEPVAEPEPNKPAAAAKTKPASPQPDLFASAAPSAVEIKLRSINPDNLTPRQALQALYDLKDIS
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: GNMT_RABIT
Sequence: MVDSVYRTRSLGVAAEGLPDQYADGEAARVWQLYIGDTRSRTSEYKTWLLGLLRQHGCRRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQPAGGGFDAVICLGNSFAHLPDCKGDQSEHRQALKNIASMVRTGGLLVIDHRNYDHILSTGCAPPGKNIYYKSDLTKDVTTSVLTVNNKAHMVTLDYTVQVPAAGQDGPPSLSKFRLSYYPHCLAPFTELLRAAFEGKCQHSVLGDFKPYQPGQAYVPCYFIHVLKRTA
What is the function of this protein?
Catalyzes the methylation of glycine by using S-adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy), a reaction regulated by the binding of 5-methyltetrahydrofolate (PubMed:4692843, PubMed:8281755).  Plays an important role in the regulation of methyl group metabolism by regulating the ratio between S-adenosyl-L-methionine and S-adenosyl-L-homocysteine (By similarity).
What are the official names of this protein?
Glycine N-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Glycine N-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCAB1_RABIT
Sequence: MLAARTGAAGSQIAEESSKLRKQAAFSGGSKDRSPKKASENVKDSSLSPSGQSQVRARQLALLREVEMNWYLKLCELSSEHTTAYTTGMPHRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS
What is the function of this protein?
Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits (By similarity).  Modulates action potentials via its effect on the pore-forming alpha subunits (By similarity).  Promotes expression of the pore-forming alpha subunits at the cell membrane, and thereby increases channel activity (By similarity).  Mediates closure of delayed rectifier potassium channels by physically obstructing the pore via its N-terminal domain and increases the speed of channel closure for other family members (By similarity).  Promotes the closure of KCNA1, KCNA2 and KCNA5 channels (By similarity).  Accelerates KCNA4 channel closure (By similarity).  Accelerates the closure of heteromeric channels formed by KCNA1 and KCNA4 (By similarity).  Accelerates the closure of heteromeric channels formed by KCNA2, KCNA5 and KCNA6 (By similarity).  Enhances KCNB1 and KCNB2 channel activity (By similarity).  Binds NADPH; this is required for efficient down-regulation of potassium channel activity (By similarity).  Has NADPH-dependent aldoketoreductase activity (By similarity).  Oxidation of the bound NADPH strongly decreases N-type inactivation of potassium channel activity (By similarity).
What are the official names of this protein?
Voltage-gated potassium channel subunit beta-1, K(+) channel subunit beta-1, Kv-beta-1.
What is the protein family that this protein belongs to?
Belongs to the shaker potassium channel beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Recruited to the cytoplasmic side of the cell membrane via its interaction with pore-forming potassium channel alpha subunits.
Protein: ENO_NITHX
Sequence: MTAIVDIIGREILDSRGNPTVEVDVALEDGAMGRAAVPSGASTGAHEAVELRDDDQTRYFGKGVRKAVDAINGEIFDAIGGMDAEQQAQIDEILIGLDGTANKSRLGANAILGVSLALARAAADSLDMPLYRYVGGVSARTLPVPMMNIVNGGVHADNPIDFQEFMIMPVGAKTFSEGLRCGSEIFHTLRAELKKAGHNTNVGDEGGFAPNLPSASAALDFIMGAIVKAGYKPGDDVALALDPAASEFFKDGKYVYAGEGKTRSIEEQARYLAKLASDYPIVSIEDGMAEDDFEGWKLLTDLIGKSCQLVGDDLFVTNVTRLADGIGKGLANSILIKVNQIGTLTETLAAVEMAYKAGYTAVMSHRSGETEDSTIADLAVATNCGQIKTGSLSRSDRAAKYNQLLRIEQQLGAQARYGGRAALKALA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: ARGR_CHLL3
Sequence: MNKHIRQQRIRELIQQEGVGNQHDLLRLLRESGIKVAQATLSRDCAELGIVRSKTHAGYRLLLGDESTGRIIKGLVGMEVTSVAANETSVIVRTLPGRAHGVGSWLDQFKSQLILGTIAGDDTVLVIPDSVQNISVLMSYIQKNLSTN
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WSDU1_MOUSE
Sequence: MVRLIHTLADHGDDVSCCAFSAALLATCSLDKTIRLYSLSDFAELPYSPLKFHTYAVHCCCFSPSGHVLASCSTDGTTVLWSSHSGHTLTVLEQPGGSPVRVCCFSPDSAYLASGAADGSIALWNAQTYKLYRCGSVKDSSLVACAFSPDGGLFVTGSSGGDLTVWDDRMRCLHSEKAHDLGITCCSFSSQPLSGGEGLQSYQLASCGQDCEIKLWAVTITRVLGFELKYKSTLSGHCAPVLACAFSHDGKMLASGSVDKSVIIHGIGPQSVLHTLTQHTRYVTTCAFAPNTLLLATGSMDKTVNIWQFDLETPCQGSMNDPLKHFTEEWSEEDVSVWLRAQGLEDLVGIFRANNIDGKELLHLTKESLAGDLKIESLGLRSKVLRSIEELRAKMDSLSSGIPDEFICPITRELMKDPVIASDGYSYEREAMESWIHKKKRTSPMTNLALPSLVLTPNRTLKMAINRWLETHEK
What are the official names of this protein?
WD repeat, SAM and U-box domain-containing protein 1.
Protein: TR106_RAT
Sequence: MLTIPEGILLCFITSGSVLGVLGNGFILHVNCTDCVRQKFSTTGFIFTGLAISRICVICIIISDGYLKLFSPHMVASDAHIIGISYLWIITNHTSTCFATILNLFYFLKIANFSHYIFFCLKRKLNTIFIFLLGCLFISWSVAFPQTVKIFNDKMKHRNTSWKFHLHKSKFIINHILLNLGVIFFCMVAIITSFLLIISLWKHNRKMQLYVSRFKSLNTEVHLKVMKVLISFIILLILHVIGILIETLSFLRYENKLLLILGLNFSSMYPCCHSFILILANNQLKQASLKALKQFKCHKKDKDVRET
What is the function of this protein?
Putative taste receptor which may play a role in the perception of bitterness.
What are the official names of this protein?
Taste receptor type 2 member 106, T2R106, Taste receptor type 2 member 19, T2R19.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PURT_BORBR
Sequence: MSTFPAPVLGTPLSPTATRVMLLGAGELGKEVVIALQRLGVEVIAVDRYADAPGHQVAHRAHVVSMTDPQALRQVIEQERPHVVVPEIEAIATDLLVALEDEGAVRVTPTARAAHLTMNREGIRRLAAETLGLPTSPYRFVDTEQALREAIDGGIGYPCVIKPVMSSSGKGQSIIRSADDIAAAWRYAQEGGRVGAGRVIVEGFIEFDYEITLLTVRARGADGQIVTQFCEPIGHRQVDGDYVESWQPHPMSPAALQRSREIALAVTGDLGGLGIFGVELFVAGDQVWFSEVSPRPHDTGMVTLISQVQNEFELHARALLGLPVDTRLRQPGASSVIYGGVEARGVAFEGVAQALAEPGTDIRLFGKPESFAKRRMGVGLAVADDVDQARAKAARVSQAVRVRAGA
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: EFTS_BURM1
Sequence: MAAITASMVAELRAKTDAPMMECKKALTEADGDMAKAEELLRVKLGNKASKAASRVTAEGVVASFVGGNAGALVELNCETDFVAKNDDFNAFAKQVAELVATKNPVDVAALSALPLDGKTVDEVRLALVGKIGENISIRRFVRFETANKLATYLHGSRIGVMVEYTGADEQVGKDVAMHVAAMKPVSLSADEVPADLIEKERRVAEQKAAESGKPAEIVAKMVDGSVQKFLKEVSLLNQPFVKNDKQTIEQMLKAANAAVQKFALFVVGEGIEKRQDDFAAEVAAQVAAAKQQ
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_SHIF8
Sequence: MSQVILDLQLACEDNSGLPEESQFQTWLNAVIPQFQEESEVTIRVVDTAESHSLNLTYRGKDKPTNVLSFPFEVPPGMEMSLLGDLVICRQVVEKEAQEQGKPLEAHWAHMVVHGSLHLLGYDHIEDDEAEEMEALETEIMLALGYEDPYIAEKE
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPC42_YEAS7
Sequence: MNGSPTPKRYSSKSSRLYDDYYNIPYQYSNPTPMNRDYNDVGSRINADKLVPEEYKRNTEFINKAVQQNKELNFKLREKQNEIFELKKIAETLRSKLEKYVDITKKLEDQNLNLQIKISDLEKKLSDANSTFKEMRFPKVKDPMVDDDPVSENYDQINVPKHRAPDATGNPRTTNKVSNTSDQDSRLKAIERTLSVLTNYVMRSEDGNNDRMSPLPSPLNTISPINNRLNFQEPKRYNPTVKVNPSDDDIMMYESAELKRVEEEIEELKRKILVRKKHDLRKLSLNNQLQELQSMMDGDDNIKLDNVSKHNHATHRHSSQSSRDYSPSSDACLECSNDLYEKNRVKPENNMSETFATPTPNNR
What is the function of this protein?
Forms a polymeric layer at the periphery of the spindle pole body (SPB) central plaque which has an essential function during SPB duplication and may facilitate attachment of the SPB to the nuclear membrane.
What are the official names of this protein?
Spindle pole body component SPC42.
What is the protein family that this protein belongs to?
Belongs to the SPC42 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body.