PharMolix/UniProtQA huggingface dataset:
Protein: CYCP_RHOCA
Sequence: ADTKEVLEAREAYFKSLGKSMKAMTGVAKSFDAEAAKAEAAALEKILATDVAPLFPAGTSSTDLPGQTEAKAAIWTNMADFGAKGKAMNDAGAEVIAAANAGDATAFGAALQKLGGTCKACHDDYREED
What is the function of this protein?
Cytochrome c' is the most widely occurring bacterial c-type cytochrome.  Cytochromes c' are high-spin proteins and the heme has no sixth ligand.  Their exact function is not known.
What are the official names of this protein?
Cytochrome c'.
Protein: ATG22_SCHPO
Sequence: MNSPIQLHKKFSTTVWHVLSWILYAVGAGPTAIISMGVYVPLIVMKNAHDHGFLRTDHTIPCSLYPEEPCSLNIVGPLWIDVSSIVFAASAISTFLQMAMMVSLGVICDYGNNRRYILFSCVIIGSISGIILSWSPSSFLLGKIVFLILVDLNFIISQSCYDSFLPIFLRFYPITRGPITLESALQDETDDLDSYITNTTIDSSEEEPYLLEHSLILNESAPPADVEDEHKAKIAARLSSVGFGSFFGAAILFQIIFTPILYKTNNNPIILPITVTVCSCWWLILSTPLCTIVTLPVENHSSDAILTLLYNSVKESYHSFKHAMSISSIRLFLFSRLFINCGIQTSLSSAVIFGKARLNLSNFQLTLLGMGISSFALLGTVIIPYLTEYFQLNSLQVVMIISILLPMAPLYGLLGYIPGFENAGIRTSADVFRATLFFGFFLGGAHSYCRSVYAQLVPSGKETRFFALYALISQTGVLFSHISLTLISNYTSDLRAVYIFVIVVMTLPLSSLWIMYQHSKTPNLHRSSS
What is the function of this protein?
Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation.  The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation.
What are the official names of this protein?
Autophagy-related protein 22.
What is the protein family that this protein belongs to?
Belongs to the ATG22 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: PMIP_MALGO
Sequence: MLSRHLTVLRSACRVSHDLRVPSTQAVRKSAWSVCYSRRPLHISRSDAASTAALDMGVAPAVEKDHEILKELLDTRHSSGHVLSQGVPTGLFQIDHLRTPSDFLLLAQRTLIRCQLLVQRIARAIGNPSELARVVRNLDRLSDMLCGVIDMAELVRHAHPDQGWANAANDAYEYLCNYMNVLNTHTELYDALRCVMETKDIYHSLSQEAQAVAHIFMRDFEKSGIHLPPHERNRFVELSDQIMILGRAFLQDMSTGTSDTIVEFPTDLLDGMDTSIFAQNLFRLRPSKSIPVVPGSWELHYISKYAPNPQARRLAYMISYTGRTQPVAVLEQLLHARYELAKLTGKQSFAEMTLVDKMAGTPEHVLRFLRLLADAQRPVAQRMIAEFGQLKHALEGSSQVEIWDREYYADAYLQRHHPSQLAPLSPYLSLGSIFTGLSRLFYLLYGIHFRAAETLPGEVWHPDVLKLEVVDETESSVIGLIYCDLYTRDGKPPSAAHYTVRCSRRIDLDDTHLDMELGASADLPPVADTEHLLGVKGATGFGRPGRFQQPVVVLMTDFAPPNIGHGGACLLRWHDVETLFHEMGHAIHSMIGRTEFHNVSGTRCATDFVELPSILMEHFLTDPSVVALTAHHHRTGSPLPYVQLQKHLATQRSLDALDTHQQILLASLDQRYHSERAGAPTFSSSQELESLQADMGLFPPVSNATWQGQFGHLFGYGATYYSYLFDRAIAARVWEQVFAKKPLSREAGERFKMEVLRHGGGKSPWEMLSRLLHEDKIADGNAGAMEAIGRWGLGQNQSNETISAHL
What is the function of this protein?
Cleaves proteins, imported into the mitochondrion, to their mature size.  While most mitochondrial precursor proteins are processed to the mature form in one step by mitochondrial processing peptidase (MPP), the sequential cleavage by MIP of an octapeptide after initial processing by MPP is a required step for a subgroup of nuclear-encoded precursor proteins destined for the matrix or the inner membrane (By similarity).
What are the official names of this protein?
Mitochondrial intermediate peptidase, MIP, Octapeptidyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M3 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: NELL2_XENLA
Sequence: MEFILGIFCVLFCLRAGAGFGVDPSLQIDIFEDLQLGEATPGVQQVQGFHNRSKAFLFQDTSRSIKASTENAERIFQKLRNKHEFTILVTLKQAMLNSGVILSIHHSDHRYLELESSGHRNEVRLHYRSGSHRSQTEVFPYILADDKWHRFSIAISASHLVLHIDCNKIYERIVEKTFMDVPPGTALWVGQRNNVHGYFKGIMQDLQIVVMPQGFISQCPDLNRTCPTCNDFHGLVQKIMELQDILAKTSAKLSRAEQRMNRLDQCYCERSCTVKGNIYRELESWMDGCKKCTCTNGTAQCETLTCSAPNCLSGFSPAYVPGKCCKECQTVCVFQGQMYFEEEREAVYSSSGQCVLFQCKDNTMRRIESPECLPLNCPQSQHITLRNSCCKVCKGHDFCSEGHNCMGYSICKNLDDKAVCICRDGFRALREDNAYCEDIDECTEGRHYCRENTVCVNTPGSFMCVCQTGYLKIDDYSCTEHNECATNQHSCDENAMCFNTVGGHNCVCQPGYTGNGTDCRAFCKDGCRNGGTCIAPNICACPQGFTGPSCESDIDECTEGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSLGGESCEDIDECATGRHSCSNDTVCFNLDGGFDCRCPHGKNCSGDCTHEGKIKHNGQIWVLENDRCSVCSCQVGLVMCRRMVCDCENPTVDLFCCPECDPRLSSQCLHQSGELTYKSGDTWVQNCQQCRCLQGEVDCWPLPCPAIDCEFSVVPESECCPRCVSDPCQADIIRNDITKTCVDETNVVRFTGSSWIKHGTECTLCQCKNGHMCCSVDPQCLQEL
What are the official names of this protein?
Protein kinase C-binding protein NELL2, NEL-like protein 2.
What are the subcellular locations of this protein?
Secreted.
Protein: RTOR1_ORYSJ
Sequence: MAPPKALETIGKTLHSQYERWQPKARYKLQLDPTLEEVKKLCNTCRKFARTERVLFHYNGHGVPKPTANGEIWVFNKSYTQYIPLPITDLDSWLKTPSIYVFDCSAAGMIVKAFLERLDWSSSSSASSSKDCILLAACEAHQTLPQSAEFPADVFTACLTTPIKMALHWFCNRSLLRDSMEHNLIDQIPGRQNDRKTLLGELNWIFTAITDTIAWNVLPHDLFQRLFRQDLLVASLFRNFLLAERIMRSANCSPISYPLLPPTHQHHMWDAWDMAAEICLSKLPQLIADPNAEFQPSPFFTEQLTAFEVWLDHGSEDKKPPEQLPIVLQVLLSQSHRFRALVLLGRFLDMGPWAVDLALSVGIFPYVLKLLQTSAMELRQILVFIWTKILSLDKSCQVDLVKDGGHAYFIRFLDSLDAYPEQRAMAAFVLAVIVDGHRVGQEACANAGLIYVCLRHLQPENPNDAQTEPLLLQWLCLCLGKLWEDFPEAQLLGLQSNAPEIVICLLSEPQPEVRASAVFALGNLVDIGSPSLNGADDDSDDDEKVRAEINVVRSLLQISSDGSPLVRSEVAVALTRFAMGHNKHIKSVAAEYWKPQTNSLLKSLPSLANINSSNVYSPSSLIQGSSGLASHIGPVLRVGSDNSATARDGRISTSSPIATNSIMHGSPQSDDSSQHSDSGILLRENASNGGLNYSRSRPIDNGIYSQFIATMCNVAKDPYPRIASIGKRALSLIGVEQVSMRNSRLSNGGAHPGETSVPPSSNFGMARSSSWFDMNSGNFSMAFRTPPVSPPQHDYLTGLRRVCSMEFRPHVLNSPDGLADPLLSSSAAPSNMGLDILPQSLIYRWSCGHFSRPLLTGSDDNEEANARREERERIAMDCIAKCQRSSCKMTSQIASWDTRFELGTKASLLLPFSPIVVAADENEQIRVWNYDDALPVNTFENHKLSDRGLSKLLLINELDDSLLLVGSSDGNVRIWRNYTQKGGQKLVTAFSSVQGYRSAGRSIVFDWQQQSGYLYASGDMSSILVWDLDKEQLVNTIQSTADSGISALSASQVRCGQFAAGFLDASVRIFDVRTPDRLVYTARPHAPRSEKVVGIGFQPGFDPYKIVSASQAGDIQFLDVRRASEPYLTIEAHRGSLMALAVHRHAPVIASGSAKQMIKVFSLEGEQLTIIRYQPSFMGQRIGSVNCLSFHRYKSLLAAGAGDNALVSIYAEDNYQVQ
What is the function of this protein?
Component of TORC1 complex, which is an essential cell growth regulator that controls plant development.  Acts by recruiting substrates for TOR.  Acts by activating transcription, protein synthesis and ribosome biogenesis, and inhibiting mRNA degradation and autophagy.
What are the official names of this protein?
Regulatory-associated protein of TOR 1, Protein RAPTOR 1, OsRAPTOR1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat RAPTOR family.
Protein: AST8_DROME
Sequence: MAALSFSPSPPPKENPKENPNPGIKTTLKPFGKITVHNVLSESGANALQQHIANQNTIIRKIRDFGMLGAVQSAAASTTNTTPISSQRKRPLGESQKQNRHNQQNQQLSKTSVPAKKCKTNKKLAVERPPKAGTISHPHKSQSDQSFGTPGRKGLPLPQAVARRNARERNRVKQVNNGFALLREKIPEEVSEAFEAQGAGRGASKKLSKVETLRMAVEYIRSLEKLLGFDFPPLNSQGNSSGSGDDSFMFIKDEFDCLDEHFDDSLSNYEMDEQQTVQQTLSEDMLNPPQASDLLPSLTTLNGLQYIRIPGTNTYQLLTTDLLGDLSHEQKLEETAASGQLSRSPVPQKVVRSPCSSPVSPVASTELLLQTQTCATPLQQQVIKQEYVSTNISSSSNAQTSPQQQQQVQNLGSSPILPAFYDQEPVSFYDNVVLPGFKKEFSDILQQDQPNNTTAGCLSDESMIDAIDWWEAHAPKSNGACTNLSV
What is the function of this protein?
Involved in the determination of the neuronal precursors of optic lobes in the central nervous system.
What are the official names of this protein?
Achaete-scute complex protein T8, Protein asense.
Protein: Y1750_CLOB1
Sequence: MDENIIINILRKEMMPGLGVTEPASIALSSAKAYEVIGGEIKNIKIIADPGLFKNAFSCAIPGTKEVGNEMAALLGTICGDASLGLECLRKIKKEDVSKAKTMLDKIDIEIKSQTEGLYVESIVTTNNGIGRTIIRYKHDNIVLVEKNNKILYQKENNLNKSNNFSQEAIDSKKITEMKLDEIVEFVNNVNYEKIEFLLESIKMNKKLSEKGLEGLGIGLGKLILESCNENNYELYAEALTCSAIDARVSGAPVPAMTVTGSGNHGIITTLPLLAIKEKKNLNNEVLARSIALSYIINIYIKEFSGKLSAFCGCAVAAGTGVSAGICYLLGGSLKEIENTIKNMASNITGMICTGGNLACSLKANTGVKAAFLSAKMALNNIVIPNKCGIVSNSIEDTMKNIGRIAYPGMMETDKEILNIMIESSK
What are the official names of this protein?
UPF0597 protein CLB_1750.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.
Protein: LIPB_ECO81
Sequence: MYQDKILVRQLGLQPYEPISQAMHEFTDTRDDSTLDEIWLVEHYPVFTQGQAGKAEHILMPGDIPVIQSDRGGQVTYHGPGQQVMYVLLNLKRRKLGVRELVTLLEQTVVNTLAELGIEAHPRADAPGVYVGEKKICSLGLRIRRGCSFHGLALNVNMDLSPFLRINPCGYAGMEMAKISQWKPEATTNNIAPRLLENILALLNNPDFEYITA
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_BURPS
Sequence: MIQTESRLEVADNTGAREVMCIKVLGGSKRRYASIGDIIKVSVKEATPRGRVKKGEIYNAVVVRTAKGVRRQDGSLIKFDGNAAVLLNNKLEPIGTRIFGPVTRELRSERFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: TT39A_DANRE
Sequence: MSTGKNAPVTENSRQMSLQACLDECMEALDLFLNNHFNESLDKLRPRSKESMYHALIYATVLEMQAMMTFQQDDIVHAGNTMKSAQEVCQRFRKKSGGLGSRGANDDLSEEQIHAEVCYAECLLHRAALTFLQDENMVSFIKGGIKVRNSYLIYKELHAFIQSDATFKGPNHKHLEGGVSFGIGAFNLTLSLFPARILKLLEFAGFSGDKEFGISQLYTGATSHTLRSMLCALLLLCFYTFLSFILGTGEGEVEEAERLLKPFRLRYPRGAIFLFFAGRAEEIKGNIDEAVALFEDGCKAQQVWKQFHHMCYWELMWCFTFKRYWKMAYFYADLLSQESRWSKAMYVYMKAAYLSMLPDSESRPFGDNEVDLFRQVPTYKQKIAGKSPPTEKFAIRKARRYKASNPVRLPVPVLEMMYMWNGFSMISKQPELTEGMMETLLEAERTLRASPDNEYTVDDTCLIQLLKGLCLKNQGQMQAAEDCFNQVYISEKKLKFDHYLVPNALLEMSLLFIDTGRKEQAIKLLQKAKNNYKVYSMESRTQFRVHAALTKLKADVSDQEEITAL
What are the official names of this protein?
Tetratricopeptide repeat protein 39A, TPR repeat protein 39A.
What is the protein family that this protein belongs to?
Belongs to the TTC39 family.
Protein: EAM_CLOD6
Sequence: MNEQTRISLERAAELKSKIDDYIQARKTINRGLEKEEEINKRKQKILSILNGTEEDWNNYKWQLSNRITDVDTLSKIITLTKKEKEYIKEVGTQFRWAISPYYLSLIDPEDICDPIKLLSIPTHIELEDEQEDLDPMGEEYTNPAGCITRRYPDRLIINVTNECAMYCRHCQRRRNIGQQDSHKSKAIIQESIDYIRENEEIRDVLVTGGDALTLKDDYLEWILSQLKEIPHVDYVRLGTRTLVTMPQRITDEFCNMLKKYHPVYINTHFNHPMEITKESKEACEKLANAGVPLGNQAVLLNGINNDKFVMRCLNQELLKIRVKPYYIFQSKHVKGTKHFNTSVDDGLEIMEYLRGYTSGMAIPTYIVNAPKGGGKTPLLPQYLVSKGTDYVMLRTWEGKVIKMEDEPAVDIKKLIKEQAQD
What is the function of this protein?
Catalyzes the interconversion of L-glutamate and L-beta-glutamate.  Does not have L-lysine 2,3-aminomutase activity.
What are the official names of this protein?
Glutamate 2,3-aminomutase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily.
Protein: SSPI_BACVZ
Sequence: MDLNLRNAVIANVTGNNQDQLEHTIVDAIQSGEEKMLPGLGVLFEVLWQHASDSEKNEMLKTLEGGLKPAQ
What are the official names of this protein?
Small, acid-soluble spore protein I, SASP I.
What is the protein family that this protein belongs to?
Belongs to the SspI family.
What are the subcellular locations of this protein?
Spore core.
Protein: FREL_CANAX
Sequence: MTESKFHAKYDKIQAEFKTNGTEYAKMTTKSSSGSKTSTSASKSSKSTGSSNASKSSTNAHGSNSSTSSTSSSSSKSGKGNSGTSTTETITTPLLIDYKKFTPYKDAYQMSNNNFNLSINYGSGLLGYWAGILAIAIFANMIKKMFPSLTNNLSGSISNLFRKHLFLPATFRKKKAQEFSIGVYGFFDGLIPTRLETIIVVIFVVLTGLFSALHIHHVKDNPQYATKNAELGHLIADRTGILGTFLIPLLILFGGRNNFLQWLTGWDFATFIMYHRWISRVDVLLIIVHAITFSVSDKATGKYKNRMKRDFMIWGTVSTICGGFILFQAMLFFRRKCYEVFFLIHIVLVVFFVVGGYYHLESQGYGDFMWAAIAVWAFDRVVRLGRIFFFGARKATVSIKGDDTLKIEVPKPKYWKSVAGGHAFIHFLKPTLFLQSHPFTFTTTESNDKIVLYAKIKNGITSNIAKYLSPLPGNTATIRVLVEGPYGEPSSAGRNCKNVVFVAGGNGIPGIYSECVDLAKKSKNQSIKLIWIIRHWKSLSWFTEELEYLKKTNVQSTIYVTQPQDCSGLECFEHDVSFEKKSDEKDSVESSQYSLISNIKQGLSHVEFIEGRPDISTQVEQEVKQADGAIGFVTCGHPAMVDELRFAVTQNLNVSKHRVEYHEQLQTWA
What are the official names of this protein?
Probable ferric reductase transmembrane component, Ferric-chelate reductase.
What is the protein family that this protein belongs to?
Belongs to the ferric reductase (FRE) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NILR1_RAT
Sequence: MTFTCKALLCLGMTLGLWITVLTEFLPRPILRVQPDTVVSTQSKVIFFCERSQGAELYCLYKKGNPRNPRCKEIRPKPGKKVEFFISKIEPYHAGHYHCYYQIHGQWSEDSDALELVVTGVYDYNELRLSVLPSPVVTVGRNMTLHCISHSHYDKFILTKEDHKFTSSLDTQCIPPSGQCQALFVMGPMTSNHTGTFRCYGYYKHTPQLWSIPSEPLEIHISGLSKKPSLLTHQGHILDPGVNLTLQCCSDINYDRFALYKVGGVDIMQHTSQQTDTGFSMTNFTLGYVHHSTGGQYRCYGAHNLSSEWSASSDPLDILITGPIQMSTLPPITSMPPDQLESYVNALIGVSVAFLVFLFILIFIILQRRHQRKFRKDGEEAQKEKELQYPTGAVEPISRDRDQQKRSNAAAATQEESVYASVEDMETEDGVELDTWKPPEGDPQGETYAQVKPSRLRRVEAIIPSAMSREQLNTKYEQAEEGQEVDGQATESEEPQDVTYAQLCSRTLRQGTAAPPLSQAGEAPEEPSVYAALATACPGAVPKDKEQ
What are the official names of this protein?
Neutrophil immunoglobulin-like receptor 1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: TPIS_BACTN
Sequence: MRKNIVAGNWKMNKTLQEGIALAKELNEALANEKPNCDVIICTPFIHLASVTPLVDAAKIGVGAENCADKASGAYTGEVSAEMVASTGAKYVILGHSERRAYYGETVAILEEKVKLALANGLTPIFCIGEVLEEREANKQNEVVAAQMESVFSLSAEDFSKIILAYEPVWAIGTGKTASPEQAQEIHAFIRSIVADKYGKEIADNTSILYGGSCKPSNAKELFSNPDVDGGLIGGAALKVSDFKGIIDAFNA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_XERMO
Sequence: MTNTRKTHPLIKIINHSFIDLPAPSNISAWWNFGSLLGLCLTIQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGLYYGSYTYFETWNIGVILLFATMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALVXVHLLFLHETGSNNPSGLVSDSDKIPFHPYYTIKDALGILLLIMALMTLVLFSPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILTLFPLLHLSKQRSMMFRPLSQCIFWILVADLFTLTWIGGQPVEYPFIIIGQLASILYFSIILLILPTASLIENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y1319_METJA
Sequence: MSYMERESWSSNLGFILASVGSAIGLGNIWRFGYMVYTNGGGAFLIPYIVALLCVGIPLMILEFAIGHYTKKSAPLALEKLHKGSEWTGWFAVISGFIITSYYVVIIAWCLYYLIILVIYGYPSDPNAYFFHNILQISSGVEDIGGVSYGILVSTLAVWGIVALILSAGIKNGLEKANKIMIPFLLFLIILLVLNALTLPGALTGIEWYLTPDFSALFNYNVWLSAFSQIFFSLSLGFGILIAYASYLPKKSDLTINAVTVSLLNCGFSFLAGFAVFGTLGYMSYTSGIPLDKAVSEGIGLAFVTFPKALSLLPFASRLFGIVFFLALVFAGISSAVSIVEASVSAIIDKFSLSRKKALLAVLALFIIISPIFTTGAGLYYLDIIDHFASGYLLPIAAILEIIIAIWLFGGDKLREHVNKLSEIKLGVWWKYLAGVVSPIILTAVVFLDASNVLTSGYGGYKTTYVIFGALIIPLAFVVSVILQKMKTIKGW
What is the function of this protein?
Putative sodium-dependent transporter.
What are the official names of this protein?
Uncharacterized sodium-dependent transporter MJ1319.
What is the protein family that this protein belongs to?
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YXEH_BACSU
Sequence: MYKLIAIDMDGTLLNDHHEVTEEVRDALHAAKAEGVKIVLCTGRPIGGVQRYLDELNLIEEGDYVIAYNGALVQNTHTNEVVSELSLGYDDLTSLYDLSLELKTPMHFFDSSNLYTPNRDISEFTVYESYVTQVPLHFRKIDEVPKDILIPKVMFIDKPENLSRVITSIPKDVREKYTMVRSAPFFYEILHSEASKGNAVRQLAQLLGIEQAEVMCIGDNGNDLTMIEWAGCGVAMANAIPEVLEAANFQTRSNNEHGVAHAIHELVLAK
What are the official names of this protein?
Putative phosphatase YxeH.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. Cof family.
Protein: SCX1_RHOJU
Sequence: KEGYPMGRNGCKISCVINNNFCKVECQAKWRQSDGYCYFWGLSCYCTNLPDDAQVWDSSTNKCGG
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
What are the official names of this protein?
Putative beta-neurotoxin RjAa1.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YCF4_CHLAT
Sequence: MTNSSIDSKSDLIRRDPVLGSRRLSNYWWATVILVGASGFFLVGISSYFGFNLVPFIKSEEILFIPQGLVMSFYGVAGILLSVYLWLTIIWNVGEGYNEYNKQDGIVRIFRWGFPGKNRRIDLVYPIQDVQAIRVEIKEGINPRRVIYLKIKGKREIPLTRIGQPLTLGEIEEKAANLARFLQVSIEGL
What is the function of this protein?
Seems to be required for the assembly of the photosystem I complex.
What are the official names of this protein?
Photosystem I assembly protein Ycf4.
What is the protein family that this protein belongs to?
Belongs to the Ycf4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ACYP_XANCP
Sequence: MQAARFIFTGVVQGVFFRASTRERALALQLRGHARNQADGSVEVVAAGSAAALEALEHWLWQGSPASKVASVTRTPCAIPTTEAFVTG
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: Y1260_MYCTO
Sequence: MKTVVVSGASVAGTAAAYWLGRHGYSVTMVERHPGLRPGGQAIDVRGPALDVLERMGLLAAAQEHKTRIRGASFVDRDGNELFRDTESTPTGGPVNSPDIELLRDDLVELLYGATQPSVEYLFDDSISTLQDDGDSVRVTFERAAAREFDLVIGADGLHSNVRRLVFGPEEQFVKRLGTHAAIFTVPNFLELDYWQTWHYGDSTMAGVYSARNNTEARAALAFMDTELRIDYRDTEAQFAELQRRMAEDGWVRAQLLHYMRSAPDFYFDEMSQILMDRWSRGRVALVGDAGYCCSPLSGQGTSVALLGAYILAGELKAAGDDYQLGFANYHAEFHGFVERNQWLVSDNIPGGAPIPQEEFERIVHSITIKDY
What are the official names of this protein?
Uncharacterized protein MT1298.
Protein: OST2_YEAST
Sequence: MAKAPKANTPKVTSTSSAVLTDFQETFKTSKRAYFAQIEKYPKLKLIDTFCFFLVLLGVIQCTFIILIRDNFPFNAFLAGFIICVGQFVLLMSLRLQLCNSFPGISKNRAFAEFIVASLILHFVCLHFIN
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2, Oligosaccharyl transferase subunit OST2, Oligosaccharyl transferase 16 kDa subunit, Oligosaccharyl transferase subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the DAD/OST2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: G6PI_CHLT2
Sequence: MMGKGFLDCESLVALQEMALHPIDLTASGCLSEERIQKNSLSVEGFTYSYATERVDDRCLEALQGLTEERELIKQMECMQQGAIMNRIEGFQSESRPVLHTATRAWVRDQDLHEEAAAIARHSKEEALRLAEFLYIARAKFSTLVQIGIGGSELGPKAMYFAMQGSCPSDKRIFFVSNIDPDNAAEVLREIDLEQTLVVVVSKSGTTLEPAANEELFRQAYQNKGLSIAEHFVAVTSQGSPMDDKSRYLEVFHLWDSIGGRFSATSMVGGVVLGFAFGYEAFIEFLQGAAAIDAHALTPKMRENLPLLSAMLGVWNRNLLGYPTTAVIPYSTGLKYFTAHLQQCGMESNGKSISREGKEISFRTSPIIWGDVGTNCQHSFFQSLHQGTDIVPVEFIGFLHNQRGLDCVLSGSSSSQKLFANLVAQSLALAQGRDNANPNKRFKGNSPSSILVAQQLSPRIAGSLLAFYEHKFAFQGFCWGINSFDQEGVSLGKELATQIIGIMSGNAPVEFPEARGVLRLFNVLT
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_CHLCV
Sequence: MSSKEIVSNRKALRNYEVLDTLEAGVVLTGTEIKSLRDHGGNLGDAYVAISKGEAWLLNASIAPYRFGNIYNHEERRKRKLLLHRYEIRKLEGRVAQKGITIIPLGMFLSRGYVKIRLGCCRGKKAHDKRQTIIAREKQREVESAMKRYR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: ARNB_ECOK1
Sequence: MSGFLPFSRPAMGVEELAAVKEVLESGWITTGPKNQALEQAFCQLTGNQHAIAVSSATAGMHITLMALEIGKGDEVITPSLTWVSTLNMISLLGATPVMVDVDRDTLMVTPEAIEAAITPRTKAIIPVHYAGAPADIDAIRAIGERYGIAVIEDAAHAVGTYYKGRHIGAKGTAIFSFHAIKNITCAEGGLIVTDNENLARQLRMLKFHGLGVDAYDRHTWGRAPQAEVLTPGYKYNLTDINAAIALTQLVKLEHLNTRRREIAQQYQQALAALPFQPLSLPAWPHVHAWHLFIIRVDEQRCGISRDALMEALKERGIGTGLHFRAAHTQKYYRERFPTLSLPNTEWNSERICSLPLFPDMTTADADRVITALQQLAGQ
What is the function of this protein?
Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase, UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase, UDP-Ara4O aminotransferase, UDP-4-amino-4-deoxy-L-arabinose aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.
Protein: DCX_HUMAN
Sequence: MELDFGHFDERDKTSRNMRGSRMNGLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYIYTIDGSRKIGSMDELEEGESYVCSSDNFFKKVEYTKNVNPNWSVNVKTSANMKAPQSLASSNSAQARENKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCLHDFFGDDDVFIACGPEKFRYAQDDFSLDENECRVMKGNPSATAGPKASPTPQKTSAKSPGPMRRSKSPADSGNDQDANGTSSSQLSTPKSKQSPISTPTSPGSLRKHKDLYLPLSLDDSDSLGDSM
What is the function of this protein?
Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development.  May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein.  May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway.  May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration.
What are the official names of this protein?
Neuronal migration protein doublecortin, Doublin, Lissencephalin-X, Lis-X.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, neuron projection. Note=Localizes at neurite tips.