PharMolix/UniProtQA huggingface dataset:
Protein: PDXD1_MOUSE
Sequence: MDASLEKIADPTLAEMGKNLKEAMRMLEKSPRRTEEENGKKPVSEDIPGPLQGSGQDMVSILQLVQNLMHGDEDEEPQSTRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSDTTLWLRRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSAAARPGLGQYLCNQLGLPFPCLCRVPCNTMFGSQHQMDVAFLEKLIKDDVERGRLPLLLVANAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAATKCDSMTLTPGLWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPADKLRALPLWLSLQYLGLDGIVERIKHACHLSQRLQESLKKVDHIKILVEDELSSPVVVFRFFQELPASDSAFKAVPVSNIAPAAVGRERHSCDALNRWLGEQLKQLVPQCGLTVIDLEVDGTCVRFSPLMTAEGLGTRGEDVDQLITCIQSKLPVLTCTLQLREEFKQEVEGTAGLLYVDDPNWPGIGVVRYEHANDDDTSLKSDPEGEKIHTGLLKKLNELESDLTFKIGPEYKSMKSCIYIGMASDDVDVSELVETIAVTAREIEENSRLLENMTEVVRKGIQEAQVQLQKANEERLLEEGVLRQIPVVGSVLNWFSPVQASQKGRSFNLTAGSLESTEYTYVHKVQGTGVTPPPTPLGTRSKQRLPGQKPFKRSLRGSDAVSETSSVSHIEDLEKVEQLSSGLEHDNLEAHSPEQPPRATDLTARQTEALQNQAQHQEDDHSQVEELERLR
What are the official names of this protein?
Pyridoxal-dependent decarboxylase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
Protein: MODC_METCA
Sequence: MEDIHARFHIDWPGFRLDVDLTLPGRGVTALFGHSGSGKTTLLRCIAGIERVSAGRLTFNGEVWQDEKIWVPTHKRPLGYVFQEASLFPHLTVLGNLRFGMKRASGPVRVSLDQAVELLGIGHLLDRKPDRLSGGERQRVAIARALAVSPRVLLMDEPLAALDLKRKQEILPYLERLHDELDIPVLYVSHSPDEVARLADHLVAMEEGRVIAAGPLKETLARLDLPIRLGEDAGAVLDAVVGERDESWHLARLDFPGGSLWTRDRGIPVGRKIRVRVLARDVSLARQRQEETSVLNLLRGRVDAIEDEDHPGLALVRVRVGESPLLARLTKRSASALGIVRGQEVWVQVKSVALME
What is the function of this protein?
Part of the ABC transporter complex ModABC involved in molybdenum import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Molybdenum import ATP-binding protein ModC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MRAY_PROM2
Sequence: MIGKINKFNFKSLLVLNTFALIATSYLFNNFIFIGVFILFFFLSLFATKNGLEIIRKLNLLQNIRTEGPSNHFQKSNTPTMGGVFLMIPFFILLLIITINLSSLKLFLLLLTIFGFYITGFLDDYLSIKNKENTGLKTKEKFILQSVISIIFILLAYEKNLINPLVILSDSWVINMNIFILPISFLVLVGISNSVNLTDGLDGLAAGCSGIVFYGLGTEILMKEQQELFVFSILCFSMSGLCLGFLKYNSYPAKIFMGDTGSLSIGATLGTIALLTNSVFTLSIFSGIFIIESLSVIIQVGVFKITKKLFHRGKRIFLMAPLHHHFELKGVKEQKIVENFWKINILLIILGIVLKIKL
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: INHA_PSEPU
Sequence: MALQIGFLLFPQVQQLDLTGPYDVLASLPDVQVHLVWKDLVPVTSSTGLQLKPTTTFEDCPVLDVICVPGGAGVGPLMEDEQTLDFIRSQAAQARYVTSVCTGSLVLGAAGLLQGKRATTHWAYHDLLPTLGAIPVKDRVVRDGNLFTGGGITAGIDFALTLAQELVGVDTAQLVQLQLEYAPAPPFDSGSPDTAPSAVVDEARKRAAPSLKLRTEITERAAAKLNLR
What is the function of this protein?
Catalyzes the hydration of cyclohexyl isocyanide to N-cyclohexylformamide.  Acts on various isonitriles, but not on nitriles or amides.  Probably involved in detoxification.
What are the official names of this protein?
Isonitrile hydratase, Cyclohexyl-isocyanide hydratase.
Protein: SECA_CLOBB
Sequence: MGLLSAVFGTYSEREVKRIRPIVSKINELDEVMQKLSDDELKAKTVEFKERLNNGETVDDILPEAFAVVREASKRVLNMKHYDEQLIGGIVLHQGRIAEMKTGEGKTLVATLPAYLNGLTGKGVHIITVNDYLAKRDAEQMGELYGFLGLTTGVIVHELTNEQRREAYNSDITYGTNNEFGFDYLRDNMVIYKEERVQRKLNFTIVDEVDSILIDEARTPLIISGQGEKSTEFYKVADYFVKTLVKEKDYTIDEKANAVMLTDEGFHKAEQTFKVENYADAENVELQHYVTQALKANYAMRRDKDYMVKDGEVIIVDEFTGRLMEGRRYSDGLHQAIEAKENVKIARESKTLATITFQNYFRMYEKLSGMTGTALTEENEFREIYGLDVIVVPTHKPVVRIDNPDLVFKSEKGKIMAVVDEIAKAHEVGQPVLVGTVSIEKSELISSMLKKKGVPHQVLNAKFHEQEAEIITHAGEKGMVTIATNMAGRGTDIKLGEGVLEIGGLKIIGTERHESRRIDNQLRGRSGRQGDSGESTFFISLEDDLMRIFGSEKIQGVVEKLGLEEDEAIESKLVSKSIENAQKKVEGNNFDIRKTLLGYDDVMNKQREVIYKQRAEVLEGEDVKEEILHMLRDVISDAVDTHIKEDAEDYRESFLYLISYLNDICIPTNEVNLPALTEMSKEEIIDHLYDVAVKSYEDKEAEFTSERLREIERVVLLRSVDTKWMDHINNMDNLKQGIGLRAFKQVDPVQAYQMEGSAMFEEMIDSIKKETVKMLLHVKVERAPERVRVAQETNAVHGDKPSAPVGPVRNLNKFGRNDVCPCGSGKKFKNCCGREA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: WDR12_ORYSJ
Sequence: MDSGGASDPSRQVRVRFLTKLPAPLRAPPTSIAVPADLTRMGLSEIVNSLLLAASPDHQAQPFDFLVDGELVRLPLQEFLLAKGISVERVLELEYVKAVAPRKQEDPCPHDDWVSAVDGSNPSFVLTGCYDGLARIWRDASECTHILEGHSDGITSARFINKGETEDRLHVVTASKDRSLRLFKFDTSVSVPKQIGAYKILRGHTSSVQSVAVDPSTNMICSGSWDNSIKLWSVEGSEEDGDTVSVKKRRTNSDSSGPEESLFEGSATSTFLGHTQCVSAVTWPERQTIYSASWDHSVRQWDVQTGKETWNMVSGKALNCLDCGGESSSLIAAGGSDPVLRVWDPRKPGTLAPIFQFSSHKSWISACKWHPSSWFHLVSSSFDGKVMLWDLRTAWPLASVESHKDKVLCADWWKGDSVISGGADSKLCIASGIEIV
What is the function of this protein?
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
What are the official names of this protein?
Ribosome biogenesis protein WDR12 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR12/YTM1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: Y1088_STRPN
Sequence: MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASVFEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEMESILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILHYAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFSYREKTDLI
What are the official names of this protein?
UPF0758 protein SP_1088.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: YUC4_ORYSJ
Sequence: MDCFAETEGKRAHDPLYQRRAAAAATPATGVPVDDVDKVVDVPGAVIVGAGPAGVAVGALLGLRGVAYVVLERCGCIASLWRHRTYDRLCLHLPKRFCELPLRPFPASFPEYPTRDQFLGYLDAYAREFGVEPVFRRAVISAEYDGESWWVYTREVVAAAAGGEQAVLGCTMTVYRSRWLVVATGENAEPVVPEMDGAGRFKGQMMHSSEYRNGDGYAGKKVLVVGCGNSGMEVSLDLCNHNARASMVVRDTVHVLPREILGFSTFGLSMWLLRWLSVQTVDWLVLLLSFLVFGDTARLGIPRPSLGPFELKSVSGKTPVLDVGTLAKIKSGDIKVTPAIQCFQEHGVEFVDGSTEEFDVVILATGYKSNVPYWLKEKEFFSEKDGFPRKGNAWKGQNGLYAVGFSRRGLSGVSMDANNIVQDIVQRLHDMGYERSENN
What is the function of this protein?
Involved in auxin biosynthesis in anthers.
What are the official names of this protein?
Indole-3-pyruvate monooxygenase YUCCA4, OsYUCCA4, Flavin-containing monooxygenase YUCCA4.
What is the protein family that this protein belongs to?
Belongs to the FMO family.
Protein: G3P_METM7
Sequence: MVNVLINGYGSIGKRVADAVAKQDDMKVIGVTKTKPDFEARMAVEKGYKLFAAIPERKHLFEEAGIPVEGTLDDIIEDADIVVDGAPKKIGKANLENVYKKHGVKAIIQGGEKAGDAQDSFNSLWSYDRCYGKDYIRLVSCNTTGLCRSMYAINSVADILKARIVLIRRAADPNDVKTGPVNAIVPNPVTVPSHHGPDVVSVIPELDGKIMTSAVIVPTTLMHMHSIMVETSGTNRDEIIDALAKTPRILTLKASEGFDSTATIIEYARDLGRSRYDLNEIAVWEESVNVVDNEVYMMQAIHQESDVIPENVDCIRAMLEMESDNLKSIEKTNKAMGLIK
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YN009_HUMAN
Sequence: MGKLRPSRGRGFADVSQQIRVRNRPSWACRRGGPLGTLLANAGPSTVPVTPTAGSCQPSPLSPGGSDPPPPPRAHVSPQEAPLGQVPGAEWLPPTRGLLCKDVSSSPGPSFHLGGPGLPGHAGPCGPRARPAQGLAGRGGNVGEGSESPLGTLPCSVPASQQLLRGRSHLQGSLAALGEARGGGAAFSWGQEGP
What are the official names of this protein?
Putative uncharacterized protein FLJ46641.
Protein: YACG_ECO45
Sequence: MSETITVNCPTCGKTVVWGEISPFRPFCSKRCQLIDLGEWAAEEKRIPSSGDLSESDDWSEEPKQ
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: MSO1_YEAST
Sequence: MMSQVSHSQEGSGRFWNKFKSSTKSLSTSLAHLSIKAEKDGDTVNTTLVHKGLVKFYENQHPFQGFPGWLGEKEDLPNERKILDTQVKHDMKKQNSRHFSPSFSNRRKASSEDPMGTPSSNGNTPEYTPASKSFQDIYNNHTSSSSATPRRASSRPTRPSAGQEFRASLGRSKTSNSFNTSSTPTPPPDASSGVMAMKDRLKRRNNDYGF
What is the function of this protein?
Involved in secretion.  Component of the secretory vesicle docking complex.
What are the official names of this protein?
Protein MSO1.
Protein: COX2_COREF
Sequence: MEQQNKRGLKRKALLGGVLGSGGLAMAGCEVSPPGGMIGDFLRMGWPSGITPEAVSMGNFWSWVWVAAWIIGIIMWGLMLTAIFSWNAKKAEKRGEGEFPKQLQYNVPLELVLTIVPIIIVMVLFFFTVQTQDRVTALDKNPEVTVNVTAYQWNWKFGYGELAPEFAPAGGDYDGVDEARQASAEASKIDPSGNNPIHGNSKKDMSYLHFNQIETLGTTDEVPVLVLPTNTPIEFNLASADVAHSFWVPEFLFKRDLYAHPEANKSQRVFQIDEIFEEGAFVGRCAEMCGTYHAMMNFELRTVDRETFAEYIAFRDANPDATNAQALEHIGEAPYATSTAPFVSDRTGTRDGENFQTPA
What is the function of this protein?
Subunits I and II form the functional core of the enzyme complex.  Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity).
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome aa3 subunit 2, Cytochrome c oxidase polypeptide II, Oxidase aa(3) subunit 2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: IF5A_NEUCR
Sequence: MSAAHDDAQHEHTFDSVDAGASATYPMQCSALRKGGHVVIKNRPCKIVDMSTSKTGKHGHAKVHLVAIDIFTGKKLEDLCPSTHNMDVPNVKRTDYQFSYIDEDFLVLIDSNGEEKRDVKMPEGELAKRIEKLEEEGKDFFVGVQTAMGEEAAIDVKEASNKD
What is the function of this protein?
mRNA-binding protein involved in translation elongation.  Has an important function at the level of mRNA turnover, probably acting downstream of decapping.  Critical for the efficient synthesis of peptide bonds between consecutive proline residues.  Can resolve ribosomal stalling caused by consecutive prolines during translation (By similarity).  Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity.  Functions as a regulator of apoptosis (By similarity).
What are the official names of this protein?
Eukaryotic translation initiation factor 5A, eIF-5A, eIF-4D.
What is the protein family that this protein belongs to?
Belongs to the eIF-5A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SF3B1_SCHPO
Sequence: MSTGTYPYKMFKMDVTNLNKVEDVEIERLRAERELLRRQKEAAKNSSTNGSVNIEGTQDSNDLQYNAHLFKSSNPKEEYDSAIDVRNDISQDEDDYKRTNDVNDSYRLVRQYEAPKELLNEYADESYDPMQERQSKKQIQDRESDYQKQRYDRQLTPTRVDAFQPDGTQSNGRSYAEVMRQVELEKEERRVHMELNQRRREGTLKEVEEEESISDKKRELELNNTEISQKPKRSRWDQAPPSVTQVSTTKRRSRWDKAPENFTISEHVIENGISEDLINKEVNVVEEKLRPPVRLLTEEELNELLPSEGYAILEPPPGYLESIHPELLQKGTTLDTYHVPQEQELPLEKELPAALPTEIPGVGDLAFFKQEDVKYFGKLLKVEDEAKLTIAELRERKILRLLLKVKNGTPPMRKSALRQLTDQARDFGAAALFNQILPLLMERTLEDQERHLLVKVIDRILYKLDDLVRPFTHKILVVIEPLLIDEDYYARAEGREIISNLAKASGLAHMIATMRPDIDHVDEYVRNTTARAFSVVASALGVPALLPFLKAVCRSKKSWQARHTGVRIIQQIALLLGCSILPHLKNLVDCIGHGLEDEQQKVRIMTALSLSALAEAATPYGIEAFDSVLKPLWSGVQRHRGKSLAAFLKATGFIIPLMEPEYASHFTRRIMKILLREFNSPDEEMKKIVLKVVSQCASTDGVTPEYLRTDVLPEFFHCFWSRRMASDRRSYKQVVETTVVLAQQVGSRQIVERVVNNFKDESEPYRKMTAETVDKVIGSLGVSEIDERLEELLLDGVLFAFQEQSVEEKVILTCFSTVVNALGTRCKPYLPQIVSTILYRLNNKSANVREQAADLVSSITIVLKACGEEALMRKLGVVLYEYLGEEYPEVLGSILGAIKAIVSVVGMSSMQPPIRDLLPRLTPILRNRHEKVQENTIDLVGKIADRGSEYVSAREWMRICFELIDMLKAHKKSIRRAAVNTFGYISKAIGPQDVLATLLNNLKVQERQNRVCTTVAIAIVAETCMPFTVVPALMADYRTPEMNVQNGVLKSLAFMFEYIGEQARDYVYAITPLLADALMDRDAVHRQTAASVIKHLSLGCVGLGVEDAMIHLLNILWPNILEESPHVINAVREGIDGIRNCIGVGPIMAYLVQGLFHPSRKVRNTYWTSYNSAYVQSADAMVPYYPHVDDDQFNNYDMKTLHICI
What is the function of this protein?
Contacts pre-mRNA on both sides of the branch site early in spliceosome assembly.
What are the official names of this protein?
U2 snRNP component prp10.
What is the protein family that this protein belongs to?
Belongs to the SF3B1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1376_NATTJ
Sequence: MNNKSKGRTAEKIARIFLLSKGYQIIFQNYRFSRLGEIDLICCFDNILIFVEVKSRSSLLWGQPEEAVGYEKQGQLKKLANIFLYEFNEFTEYQIRFDVIAILNNNKVKCEISHLRDAF
What are the official names of this protein?
UPF0102 protein Nther_1376.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: CLP1_CAEBR
Sequence: MGEEQVQEFKLKEDCELRFAAGEDSEVVLELVHGYAEIFGTEIILNKKYNFPAKSRVAVFTWKSATIELVGATESAYVAESTPMVIYLNIHAAMEESRKKREEQAVSNSSKPKGPRLLLVGPQDVGKTTVSRILCNYSVRHGRTPILVDLDVGQNSVSVPGSVAALLVQKTADVVDGFERNMPIVYNFGHSSPSQNLSLYETLFKALASTINSQIEQNDEARLGGMIINTCGWVDGEGYKCIVKAASAFEVDVVIVLDHERLYSDLSKELPEFVRLTHVPKSGGVEQRTAQIRSATRGENVHRYFYGTRANNLFPFTFDVPFDTVTLCKIGAEQLPDSCLPFGMEVENHETKIIIIEPSVEIKHHLFSFSRGSIAEKNVLTSSVWGFCLITEVDMEKRTISILCPQNTIPSKTLVYSEVTHLDDQIER
What is the function of this protein?
Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.
What are the official names of this protein?
Protein clpf-1.
What is the protein family that this protein belongs to?
Belongs to the Clp1 family. Clp1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PRR29_MOUSE
Sequence: MASLGSGNWSGVPTQSTAPMPWVTILQPFPWTVPSSQPQHNRVKEDLLELMMLQNAQMHQLLLGQLVADALNPGPEWPSPPVHTDSHEEQMEEEMEMQEQEPLVYHHHYLPCPVTPLGPMSLWPASFLPVPPHQPPWQGEPRIQHQPPASRQEEVRDVPPPPPPSATGTVGADVPPASDYYDAESLP
What are the official names of this protein?
Proline-rich protein 29.
Protein: TRPB_AERS4
Sequence: MTLLNPFFGEFGGMYVPQILIPALLQLEKAFVDAQEDPAFIAEFQELLTEYAGRPTPLTLTRNLTKGTKTRLYLKREDLLHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVATALACALLGLKCRVYMGAKDCERQKPNVFRMKLMGATVIPVHSGSSTLKDACNEALRDWAASYDNAHYLLGTAAGPHPFPTIVREFQKMIGEEAKAQCFKKEERLPDAVIACVGGGSNAIGMFADFIDNKEVRLIGVEPGGHGIESGEHGAPLGHGSKGVFFGMHSYLMQDKQGQIQESYSVSAGLDFPSVGPQHAHLASIGRAEYVSITDKEALDAFQELAKSEGIIPALESSHALAHALKMARSEPEKELVLIVNLSGRGDKDIFTVADIFEKEGTLS
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: COXX1_BACCN
Sequence: MGRKKEVTNAQRQRPEILAQTIKTGIIKSNLVPMFAGLTLALYKYKISPFEKIPEILFAFIGSILIIGAAGAFNNLYDRDIDSIMERTKNRPTVTGDISPKTALWLGIFMTIFGLVFLALTTYLAAILGFIGLFLYVVPYTMWSKRRTIYNTEIGSVSGAMPPLIGWAAIYPDVTHPAIIGLFIIMIIWQMPHFYAIAIRKHKEYEAANVPMLPVVKGVKRTYIQTNVYLVILIIISILLGSLSIGLMLVSLLLSILWLALSIYGYKKMDSEKWAKSLFIFSLFHMTILFSTVIIYSLVGIFFGS
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase 1, Heme B farnesyltransferase 1, Heme O synthase 1.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HEMH_SALEP
Sequence: MRQTKTGILLANLGTPDAPTPEAVKRYLKQFLSDRRVVDTPRLLWWPLLRGVILPLRSPRVAKLYQSIWMDGGSPLMVYSREQQQALAARLPDTPVALGMSYGSPSLESAVDELLASDVDHIVVLPLYPQYSCSTVGAVWDELGRILARKRRIPGISFIRDYADDSAYIDALAKSARESFARHGEPDVLLLSYHGIPQRYADEGDDYPQRCRDTTRELVSALGLPPEKVMMTFQSRFGREPWLTPYTDETLKMLGEKGTGHIQVMCPGFAADCLETLEEIAEQNREIFLEAGGKKYAYIPALNATPEHIDMMLKLTAPYR
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTL_STAAR
Sequence: MGKIKELQTSLANKIAAGEVVERPSSVVKELLENAIDAGATEISIEVEESGVQSIRVVDNGSGIEAEDLGLVFHRHATSKLDQDEDLFHIRTLGFRGEALASISSVAKVTLKTCTDNANGNEIYVENGEILNHKPAKAKKGTDILVESLFYNTPARLKYIKSLYTELGKITDIVNRMAMSHPDIRIALISDGKTMLSTNGSGRTNEVMAEIYGMKVARDLVHISGDTSDYHIEGFVAKPEHSRSNKHYISIFINGRYIKNFMLNKAILEGYHTLLTIGRFPICYINIEMDPILVDVNVHPTKLEVRLSKEEQLYQLIVSKIQEAFKDRILIPKNNLDYVPKKNKVLHSFEQQKIEFEQRQNTENKQEKTFSSEESNSKPFMAENQNDEIVIKEDSYNPFVTKTSESLIADDESSGYNNTREKDEDYFKKQQEILQEMDQTFDSNDDTSVQNYENKASDDYYDVNDIKGTKSKDPKRRIPYMEIVGQVHGTYIIAQNEFGMYMIDQHAAQERIKYEYFRDKIGEVTNEIQDLLIPLTFHFSKDEQLVIDQYKNELQQVGIMLEHFGGHDYIVSSYPVWFPKDEVEEIIKDMIELILEEKKVDIKKLREDVAIMMSCKKSIKANHYLQKHEMSDLIDQLREAEDPFTCPHGRPIIINFSKYELEKLFKRVM
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: RL331_STRT1
Sequence: MAQKKASLACADCGNRNYSISVSSTPKPTRLEVNKFCKNCKKYTLHKETR
What are the official names of this protein?
50S ribosomal protein L33 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: TRAM8_ECOLX
Sequence: MPKIQTYVNNNVYEQITDLVTIRKQEGIEEASLSNVSSMLLELGLRVYMIQQEKREGGFNQMEYNKLMLENVSRVRAMCTEILKMSVLNQESIASGNFDYAVIKPAIDKFAREQVSIFFPDDEDDQE
What is the function of this protein?
Conjugative DNA transfer (CDT) is the unidirectional transfer of ssDNA plasmid from a donor to a recipient cell.  It is the central mechanism by which antibiotic resistance and virulence factors are propagated in bacterial populations.  Part of the relaxosome, which facilitates a site- and strand-specific cut in the origin of transfer by TraI, at the nic site (By similarity).  TraM binds to three principal regions in the oriT (transfer origin) region; 2 are required for autoregulation while the other is required for plasmid transfer.  Plasmid specificity is conferred by the TraD-TraM pair.
What are the official names of this protein?
Relaxosome protein TraM.
What is the protein family that this protein belongs to?
Belongs to the relaxosome TraM family.
What are the subcellular locations of this protein?
Cytoplasm. Note=To a smaller extent in the inner membrane by association with another protein, probably TraD.
Protein: LYS4_DEBHA
Sequence: MALLYLSTRSSLKKTGARCLSSSSILYRGQNLTEKIVQKYAVGLADDKKVFSGDYVTIKPAHCMSHDNSWPVATKFMGLGATNVHDNRQIVCTLDHDVQNKSEKNLEKYHNIENFAKEQGIDFYPAGRGIGHQIMIEEGYAYPLNLTVASDSHSNTYGGIGSLGTPIVRTDAASIWATGQTWWQIPPVAKVELVGQLPKGATGKDIIVALCGIFNNDEVLNHAIEFTGEGVKNLSVDYRLTIANMTTEWGALSGLFPVDETLVNFYDERVKKLPQPHPRVNENTVKNLSENKVNSDNDAVYAKHLVVDLSSLSPYISGPNSVKVSTSLHDLSKQNIKINKAYLVSCTNSRLSDIKAAADIIKGHKVAEGVEFYVAAASSNVQKDAEAIGAWQDIIDAGAKPLPAGCGPCIGLGTGLLEDGEVGISATNRNFKGRMGSKDALAYLASPEVVAASAVLGKIGGPEELQGNPVPTNPEIVRSITSNESTETVDPDASGSSVDVLDGFPQSIEGELILCDADNINTDGIYPGKYTYQDDIPRSKMAEVCMENYDSEFKQKTKAGDIIISGYNFGTGSSREQAATAILARDMKLVVAGSFGNIFSRNSINNALLTLEIPALINKLREKYAQSNELTIRTGWFLKWDVTKNQVTVSDSEGNLILTQKVGELGTNLQDIIVKGGLEGWVKAQLKN
What is the function of this protein?
Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.
What are the official names of this protein?
Homoaconitase, mitochondrial, Homoaconitate hydratase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: BIOB_AFIC5
Sequence: MNISMGISSLSVINGSALPRHNWAREEAQALYDLPFPDLVFQAQSIHRTSFDPNHVETASLLSIKTGGCAEDCGYCSQSAHYKTDVKATKLMAHDDVVATARRAKESGAGRFCMAAAWRNPKEKDLERICHMVSAVKELGMETCATLGMLTREQADKLRAAGLDFYNHNVDTSPEFYGKIITTRTLQDRIETLAHARESGLKVCCGGIVGLGEQVEDRLGMLVLLANLAEHPESVPINQWNEVKGVPVNATAEAPDPIAFVRMIAVARIMMPKSVVRLSAGRQYMSDEMQALCMLAGANSIFIGDVLLTTKNPQTTKDAALLERLGMTSRFDEVATDKANPVSSRAI
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: ODF3A_BOVIN
Sequence: MAEEVWVGTWRPHRPRGPIMALYSSPGPKYLIPPTTGFVKQTPTKLRAPAYSFRGAPMLLAENCSPGPRYSVNPKILRTGKDLGPAYSILGRYHTKTTLTPGPGDYFPEKSTKHVFDSAPSHSISARTKTFRVDSTPGPAAYMLPMVMGPHTIGKVSQPSFSIKGRSKLGSFSDDLHKTPGPAAYRQTDVQVTKFKAPQYTMAARVEPPGDKTLKPGPGAHSPEKVTMTRPCAPVVSFGIKHSDYMTPLVVDVD
What is the function of this protein?
Outer dense fibers are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail.  May help to maintain the passive elastic structures and elastic recoil of the sperm tail.
What are the official names of this protein?
Outer dense fiber protein 3, Outer dense fiber of sperm tails protein 3.
What is the protein family that this protein belongs to?
Belongs to the ODF3 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Expressed in the cytoplasmic lobe of spermatids.
Protein: RL4_YERPN
Sequence: MELVMKDAPGALTVSETTFGRDFNEALVHQVVVAYAAGARQGTRAQKTRAEVTGSGKKPWRQKGTGRARAGSVKSPIWRSGGVTFAAKPQDHSQKVNKKMYRGALKSILSELVRQDRLIIVEKFSVEAPKTKLLAQKLKDMALEDVLIVTGELDENLFLAARNLYKVDVRDVAGIDPVSLIAFDKVVMTADAVKQVEEMLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: SUMO1_CHICK
Sequence: MSDQEAKPSAEDLGDKKEGEYIKLKVIGQDSSEIHFKVKMTTHLKKLKESYCQRQGVPMNSLRFLFEGQRITDNHTPKELGMEEEDVIEVYQEQTGGHSTV
What is the function of this protein?
Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer.  Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I.  This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction.  Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins.
What are the official names of this protein?
Small ubiquitin-related modifier 1, SUMO-1.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family. SUMO subfamily.
What are the subcellular locations of this protein?
Nucleus membrane. Nucleus speckle. Cytoplasm. Nucleus, PML body. Cell membrane. Nucleus.