PharMolix/UniProtQA huggingface dataset:
Protein: KDPA_CLAMS
Sequence: MDTLAGILQVASVVLVLVLVHRPLGDLMARMYESRHDTRVERGIYRLIGVDPRSEQTWPAYLRAVLAFSLVGVLVVYGMQRLQAFLPYALGLPAVPEGISFNTAVSFVTNTNWQSYSPEATMGYTVQLAGLAVQNFVSAAVGIAVAIALVRGFARTRSGTIGNMWVDLIRGSLRLLLPLSLVTAVVLIAGGVIQNFAGFQDVQTLAGGTQTIPGGPVASQEAIKMLGTNGGGFFNANSAHPFEDPTAWTSAFQVLLMLVIPFSLPRTFGKMVGDTRQGTAIAAVMATIAVASLTALTLFELQGAGSAPMAAGAAMEGKEQRVGIIGSALFGTVSTLTSTGAVNSMHDSYTALGGMMPMLNMMLGEVAPGGVGSGLYGMLVLAVIAVFVAGLLVGRTPEYLGKKIGPREIKLASLYILVTPILVLVGTALSFAIPAVRDDVEGTSILNSGLHGLSEVVYAFTSAANNNGSAFAGLTASTPWFTTALGVAMLLGRFVPIVLVLALAGSLAAQDRIPTTSGTLPTHRPQFVGLLIGVTVIVTALTYFPVLALGPLAEGLAS
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PAT16_SOLTU
Sequence: MATTKSFLILIVMILATTSSTFASLEEMVTVLSIDGGGIKGIIPGTILEFLEGQLQKMDNNADARLADYFDVIGGTSTGGLLTAMITTPNENNRPFAAANEIVPFYFEHGPHIFNSSTGQFFRKYDGKYLMQVLQEKLGETRVHQALTEVAISSFDIKTNKPVIFTKSNLAKSPELDAKMYDICYSTAAAPTYFPPHYFATNTINGDKYELNLVDGAVATVADPALLSVSVATRRAQEDPAFASIRSLNYKKMLLLSLGTGTTSEFDKTHTAEETAKWGALQWMLVIQQMTEAASSYMTDYYLSTVFQDLHSQNNYLRVQENPLTGTTTKADDASEANMELLAQVGENLLKKPVSKDNPETYEEALKRFAKLLSDRKKLRANKASY
What is the function of this protein?
Probable lipolytic acyl hydrolase (LAH), an activity which is thought to be involved in the response of tubers to pathogens.
What are the official names of this protein?
Patatin-16.
What is the protein family that this protein belongs to?
Belongs to the patatin family.
What are the subcellular locations of this protein?
Vacuole.
Protein: KLRD1_MACMU
Sequence: MAVFKTTLWRLISGTLGIICLSLMATLGILLKNSFTKLSVEPAYTPGPNIELQKDSDCCSCHEKWVGYRCNCYFISSEEKTWNESRHFCASQKSSLLQLQNRDELDFMSSSQHFYWIGLSYSEEHTAWLWENGSALSQYLFPSFETFKPKNCIAYNSKGNALDESCETKNRYICKQQLI
What is the function of this protein?
KLRD1-KLRC2 acts as an immune activating receptor.  On cytotoxic lymphocyte subsets recognizes MHC-E loaded with signal sequence-derived peptides from non-classical MHC class Ib MHC-G molecules, likely playing a role in the generation and effector functions of adaptive NK cells and in maternal-fetal tolerance during pregnancy.  Regulates the effector functions of terminally differentiated cytotoxic lymphocyte subsets, and in particular may play a role in adaptive NK cell response to viral infection.  Upon MHC-E-peptide binding, transmits intracellular signals via the adapter protein TYROBP/DAP12, triggering the phosphorylation of proximal signaling molecules and cell activation.
What are the official names of this protein?
Natural killer cells antigen CD94, Killer cell lectin-like receptor subfamily D member 1, NK cell receptor.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: ASPA_PROMP
Sequence: MTLKKILIVSGTHGNEINPVWAINQFNKQFKTIDKNIEYKFVIGNPLAYERGCRYIDNDLNRSFTSIQDNSIYETNRANFLVEKFGFNGSEPCDVAIDLHTTTANMGTSIVMYGRRMKDFCLAALLQHKFGLPIYLHEKDLKQTGFLVEAWPCGLVLEIGSVAQNFYDPKIINRFLIIISSLRDEINKLKNNQIRLPKDLFVHVHQGSIDYPRDKNGNINALIHPERINQDWKPIKKDAPLFMDMEGKTKTYADEDTIWPVFIGEVAYKEKNIAMSFTKKEVVSVSDQMYEEFFS
What are the official names of this protein?
Probable aspartoacylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Aspartoacylase subfamily.
Protein: IHFB_RHOPB
Sequence: MIKSELVQRIAEHNPHLYQRDVENIVNAILDEIVAALARGDRVELRGFGAFSVKHRPARAGRNPRTGAHVPVDQKSVPFFKTGKEMRERLNRDTGAPDSGA
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: ELOV4_HUMAN
Sequence: MGLLDSEPGSVLNVVSTALNDTVEFYRWTWSIADKRVENWPLMQSPWPTLSISTLYLLFVWLGPKWMKDREPFQMRLVLIIYNFGMVLLNLFIFRELFMGSYNAGYSYICQSVDYSNNVHEVRIAAALWWYFVSKGVEYLDTVFFILRKKNNQVSFLHVYHHCTMFTLWWIGIKWVAGGQAFFGAQLNSFIHVIMYSYYGLTAFGPWIQKYLWWKRYLTMLQLIQFHVTIGHTALSLYTDCPFPKWMHWALIAYAISFIFLFLNFYIRTYKEPKKPKAGKTAMNGISANGVSKSEKQLMIENGKKQKNGKAKGD
What is the function of this protein?
Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle.  This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle.  Condensing enzyme that catalyzes the synthesis of very long chain saturated (VLC-SFA) and polyunsaturated (PUFA) fatty acids that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.  May play a critical role in early brain and skin development.
What are the official names of this protein?
Elongation of very long chain fatty acids protein 4, 3-keto acyl-CoA synthase ELOVL4, ELOVL fatty acid elongase 4, ELOVL FA elongase 4, Very long chain 3-ketoacyl-CoA synthase 4, Very long chain 3-oxoacyl-CoA synthase 4.
What is the protein family that this protein belongs to?
Belongs to the ELO family. ELOVL4 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ARI13_ARATH
Sequence: MENNREGPYSVLTRDQLKGNMKKQIAEISEIFSLSKPDATVLLMFLRWDSHEVSEFLVENNEKVLSESGLKPVVVDPNQDLYKISSCGICFKTCDDGDYLISTPFCSHMFCKSCWRKYLEKNFYLVEKTQTRISCPHGACQAAVGPDTIQKLTVCDQEMYVEYILRSYIEGNKVLEIKYCPAQDCNYVIEFHQKNHDGADQEDYGFNVVCLCGHIFCWRCMLESHKPVTCNNASDWLFRDLNSLSKESGEKPLSLSSFETREKTYPLSSIKATKKVCPHCLRPADLGTKQYLRFLTCACNGRFCWKCMQPEEAHKTESGFYKFCNVSMTFEGRAPKTLEGRAEPENSCVGLWKASEVSLKQAKSDLQAFEESNIKNPSDLTEKDFTIIRKGLMLIVQCRQVLKWSCVYDYLHAEYEMSKREYLRFLQADATSLVESFSKTLNEEIGRASSATYENFCCVKHKVTIETSNIGNYFYHFIKTLQEGLDDVKVKSYDDYGGLFWLCDRCTYGNTWFHKECLMCSDDIAARVDLSDMSLN
What is the function of this protein?
Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates.
What are the official names of this protein?
Probable E3 ubiquitin-protein ligase ARI13, ARIADNE-like protein ARI13, Protein ariadne homolog 13, RING-type E3 ubiquitin transferase ARI13.
What is the protein family that this protein belongs to?
Belongs to the RBR family. Ariadne subfamily.
Protein: ANM7_XENLA
Sequence: MKVFCGRVNPTTGAMDWVEEDEHYDYHQEIARSSYADMLHDKDRNEKYYQGICAAVRRVKQRGQEAVVLDIGTGTGLLSMMAVTAGADCCYAIEVFKPMSDAAVQIVKANGFSDKIKVINKHSTEVTVGPDGDMKTKANILITELFDTELIGEGALPSYEHAQHNLMQETWEAVPHRATVFAQLVESTRLWSWNKLFPLNLETGDIKPHPELETCPGAPSVCDIQLSQLNPRDFKILSEVLCVFRVDFSCQVSSAPTSHPVHFTSLASGAAQVVLSWWEIDMDPDGSITCTMQPSWMYETQQSVPWRDHWMQCVYFLPKECSVTQGEVCCLTAHQDDYCVWYSLNKSSAENDPVCRERPTCHCGAHITWNRARFGELNDRHRTQQYFEALKKVVTPSSTCLCVSDGSLLPVLAHSLGAKQIYTLESSSIAQHLMKKLFQVNHLGEKIQVLHKSADSLITADFEDRKISTLIGEPFFTTNLLPWHNLYFWYSRTALSTNLAKDCTVLPLSASLHVVAVEFKDLWRIRSPCGMCEGFDVSIMDKMIKNSLNFRESQEAEPHPLWEYPCRALSEPIQVMTFNFTEPVPTEEIRASGSLNLVRSGQCHGAVLWMVYELTKEITVSTGLIGISEEMGECQWYPHRKQGVYFFSSILNPQTIPAQSPSSVSYSVTFIPKEGDIRMCFEPDF
What is the function of this protein?
Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA.  Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles.  Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s.  Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites.  May also play a role in embryonic stem cell (ESC) pluripotency.  Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo.
What are the official names of this protein?
Protein arginine N-methyltransferase 7, Histone-arginine N-methyltransferase PRMT7, [Myelin basic protein]-arginine N-methyltransferase PRMT7.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT7 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus.
Protein: VKGC_RAT
Sequence: MAVHRGSARAAPASDKVQKNKPAQTSGLEQGSRMARIFGFEWADLSSWQSVVTLLNRPTDPANLAVFRFLFAFLMLLDIPQERGLSSLDRKYLDGLDVCRFPLLDALRPLPLDWMYLVYTIMFLGALGMMLGLWYRLSCMLFLLPYWYVFLLDKTSWNNHSYLYGLLAFQLTFMDANHYWSVDGLLSAQKKNAHVPLWNYTVLRGQIFIVYFIAGVKKLDADWVEGYSMEHLSRHWLFSPFKLVLSEELTSLLVVHWCGLLLDLSAGFLLFFDASRPIGLVFVSYFHCMNSQLFSIGMFPYVMLASSPLFCSAEWPRKLVARCPKRLQELLPAKAAPRPSASCVYKRARAKAGQKPGLRHHLGTVFTLLYLLEQLFLPYSHFLTQGYNNWTNGLYGYSWDMMVHSRSHQHVKITYRDGLTGELGYLNPGVFTQSRRWKDHADMLKQYATCLSLLLPKYNVTEPQIYFDIWVSINDRFQQRLFDPRVDIVQAVWSPFRRTPWVQPLLMDLSPWRTKLQDIKSSLDNHTEVVFIADFPGLHLENFVSEDLGNTSIQLLQGEVTVELVAEQKNQTLREGEKMQLPAGEYHKVYTVSSSPSCYMYIYVNTTEVALEQDLAYLQELKEKVENGSETGPLPPELQPLLEGEVKGGPEPTPLVQTFLRRQRKLQEIERRRNSPLHERFLRFVLRKLYVFRRSFLMTRISLRNLLFGRPSLEQLAQEVTYANLRPFEPVDESSASNTDSSDPHPSEPDSEHVHSEL
What is the function of this protein?
Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide.
What are the official names of this protein?
Vitamin K-dependent gamma-carboxylase, Gamma-glutamyl carboxylase, Peptidyl-glutamate 4-carboxylase, Vitamin K gamma glutamyl carboxylase.
What is the protein family that this protein belongs to?
Belongs to the vitamin K-dependent gamma-carboxylase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: U2QL1_HUMAN
Sequence: MKELQDIARLSDRFISVELVDESLFDWNVKLHQVDKDSVLWQDMKETNTEFILLNLTFPDNFPFSPPFMRVLSPRLENGYVLDGGAICMELLTPRGWSSAYTVEAVMRQFAASLVKGQGRICRKAGKSKKSFSRKEAEATFKSLVKTHEKYGWVTPPVSDG
What is the function of this protein?
Probable E2 ubiquitin-protein ligase that catalyzes the covalent attachment of ubiquitin to target proteins.  May facilitate the monoubiquitination and degradation of MTOR and CCNE1 through interaction with FBXW7.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2Q-like protein 1, E2Q-like ubiquitin-conjugating enzyme 1.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL21_SYMTH
Sequence: MTYAIVETGGKQYRVQEGDTLRVEKLTAGEGETVVFDKVLAISRDGKVTVGTPYIEGAKVTAKVAAHGKGPKIIVFKYRNKTNYRRKTGHRQPFTAITIESIEG
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: TPIS_MACFA
Sequence: MAPSRKFFVGGNWKMNGRKQNLGELIGTLNAAKVPADTEVVCAPPTAYIDFARQKLDPKIAVAAQNCYKVTNGAFTGEISPGMIKDCGATWVVLGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKVIADNVKDWSKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSNVSEAVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPEFVDIINAKQ
What is the function of this protein?
It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
What are the official names of this protein?
Triosephosphate isomerase, TIM, Methylglyoxal synthase, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XYLB_HUMAN
Sequence: MAEHAPRRCCLGWDFSTQQVKVVAVDAELNVFYEESVHFDRDLPEFGTQGGVHVHKDGLTVTSPVLMWVQALDIILEKMKASGFDFSQVLALSGAGQQHGSIYWKAGAQQALTSLSPDLRLHQQLQDCFSISDCPVWMDSSTTAQCRQLEAAVGGAQALSCLTGSRAYERFTGNQIAKIYQQNPEAYSHTERISLVSSFAASLFLGSYSPIDYSDGSGMNLLQIQDKVWSQACLGACAPHLEEKLSPPVPSCSVVGAISSYYVQRYGFPPGCKVVAFTGDNPASLAGMRLEEGDIAVSLGTSDTLFLWLQEPMPALEGHIFCNPVDSQHYMALLCFKNGSLMREKIRNESVSRSWSDFSKALQSTEMGNGGNLGFYFDVMEITPEIIGRHRFNTENHKVAAFPGDVEVRALIEGQFMAKRIHAEGLGYRVMSKTKILATGGASHNREILQVLADVFDAPVYVIDTANSACVGSAYRAFHGLAGGTDVPFSEVVKLAPNPRLAATPSPGASQVYEALLPQYAKLEQRILSQTRGPPE
What is the function of this protein?
Phosphorylates D-xylulose to produce D-xylulose 5-phosphate, a molecule that may play an important role in the regulation of glucose metabolism and lipogenesis.
What are the official names of this protein?
Xylulose kinase, Xylulokinase.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: UPPP_PARDP
Sequence: MDHNTIVAAALGLLEGLTEFIPVSSTGHVLLAGHFLGFDSPGRAFEVLIQLGAIMAILGVYAGRLWRIFSSAPQDPRARRFILAVLLAFLPAVVIGVLAHRIIKEVLFETPTLIAVMLIVGGVVLLFVDRMANRPRHFSAEDFPLPMALKIGFIQCLAMIPGVSRSGATIVGALLLGADKRSAAEFSFFLSMPTMLGAFVYDLYKNRDILDAAATGNIVIGFVCAFLAAVVVVRGLLNYVSTYGYGLFAWWRIAVGVAVLLALQAGW
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IL8_DASNO
Sequence: MTSKLAIALLATFMLSAALCEAAVLSRSGTELRCLCINTHSTYFHPRVIKELRVIESGPHCPNTEIMSVKLVNGAEVCLDPKQKWVQKVVELFLKR
What is the function of this protein?
Chemotactic factor that mediates inflammatory response by attracting neutrophils, basophils, and T-cells to clear pathogens and protect the host from infection.  Also plays an important role in neutrophil activation.  Released in response to an inflammatory stimulus, exerts its effect by binding to the G-protein-coupled receptors CXCR1 and CXCR2, primarily found in neutrophils, monocytes and endothelial cells.  G-protein heterotrimer (alpha, beta, gamma subunits) constitutively binds to CXCR1/CXCR2 receptor and activation by IL8 leads to beta and gamma subunits release from Galpha (GNAI2 in neutrophils) and activation of several downstream signaling pathways including PI3K and MAPK pathways.
What are the official names of this protein?
Interleukin-8, IL-8, C-X-C motif chemokine 8, Chemokine (C-X-C motif) ligand 8.
What is the protein family that this protein belongs to?
Belongs to the intercrine alpha (chemokine CxC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y3965_PARDP
Sequence: MIVTTTPGIEGRRISAYHGVVTGETIIGANIFRDIFAGIRDIVGGRAGAYESALASARETALSEMQDRARQLGGNAVVGVDLDYEVINNMLMVSASGTAVSVE
What are the official names of this protein?
UPF0145 protein Pden_3965.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: HIBC4_ARATH
Sequence: MHNAKGLLGRIVRDKLWRFGYRRSLCSLKLTSEDLDYQVLVEGSGCSRTAILNRPPALNALTTHMGYRLQKLYKNWEEDPNIGFVMMKGSGRAFCAGGDIVSLYHLRTRGSPDAIREFFSSLYSFIYLLGTYLKPHVAILNGVTMGGGTGVSIPGTFRVATDRTIFATPETIIGFHPDAGASFNLSHLPGRLGEYLGLTGLKLSGAEMLACGLATHYIRSEEVPVMEEQLKKLLTDDPSVVESCLEKCAEVAHPEKTGVIRRIDLLEKCFSHDTVEEIIDSLEIEASRRKDTWCITTLRRLKESSPLSLKVALRSIREGRLQTLDQCLIREYRMSLQGLIGPMSGNFCEGVRARLIDKDEAPKWDPPSLEKVSEDMVDDYFCALTPTEPDLDLPVKLRESI
What are the official names of this protein?
3-hydroxyisobutyryl-CoA hydrolase-like protein 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TATA_HISS2
Sequence: MGLSWQQLLILLLVVVVIFGTKKLRNIGSDLGGAVKDFKKAMNDDQPKDAEFKKISEEVEQTSVENSKQKEQA
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PMK_ARATH
Sequence: MAVVASAPGKVLMTGGYLVLEKPNAGLVLSTNARFYAIVKPINEEVKPESWAWKWTDVKLTSPQLSRESMYKLSLNHLTLQSVSASDSRNPFVEHAIQYAIAAAHLATEKDKESLHKLLLQGLDITILGSNDFYSYRNQIESAGLPLTPESLGTLAPFASITFNAAESNGANSKPEVAKTGLGSSAAMTTAVVAALLHYLGVVDLSDPCKEGKFGCSDLDVIHMIAQTSHCLAQGKVGSGFDVSCAVYGSQRYVRFSPEVLSFAQVAVTGLPLNEVIGTILKGKWDNKRTEFSLPPLMNLFLGEPGSGGSSTPSMVGAVKKWQMSDPEKARENWQNLSDANLELETKLNDLSKLAKDHWDVYLRVIKSCSVLTSEKWVLHATEPINEAIIKELLEAREAMLRIRILMRQMGEAASVPIEPESQTQLLDSTMSAEGVLLAGVPGAGGFDAIFAITLGDSGTKLTQAWSSHNVLALLVREDPHGVCLESGDPRTTCITSGVSSIHLE
What are the official names of this protein?
Phosphomevalonate kinase, peroxisomal, 5-phosphomevalonate kinase, AtPMK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
What are the subcellular locations of this protein?
Peroxisome.
Protein: M18BP_MOUSE
Sequence: MIVTPLKHSGIHLSSGTLQRRNMPLDAVFIDSIPSGTLTPLKDLVKYQKSSLKVNGHKKNQLLEIRTSNNKDLFQSTMLSEATLPNSSLDISVIKPSMDRLRNEMIYESPGKIFQRMKAKVQRDKQEQLTRSSSMLGSPQGEHTKDFPPNTDKKAQLQQTYICEEKQTSVQSNDPSLGDPPILNQEQKNVSASCISKKALTRAQFGGQVLHSKESPVRITVSKKNTFVLGGIDCTYEKFENTDVNTISSLCVPIKNHSQSITSDNDVTTERTAKEDITEPNEEMMSRRTILQDPIKNTSKIKRSSPRPNLTLSGRSQRKCTKLETVVKEVKKYQAVHLQEWMIKVINNNTAICVEGKLVDMTDVYWHSNVIIERIKHNELRTLSGNIYILKGLIDSVSMKEAGYPCYLTRKFMFGFPHNWKEHIDKFLEQLRAEKKNKTRQETARVQEKQKSKKKDAEDKETYVLQKASITYDLNDNSLERTEVPTDPLNSLEQPTSGKERRHPLLSQKRAYVLITPLRNKKLIEQRCIDYSLSIEGISDFFKAKHQEESDSDIHGTPSSTSKSQETFEHRVGFEGNTKEDCNECDIITARHIQIPCPKSKQMLTNDFMKKNKLPSKLQKTENQIGVSQYCRSSSHLSSEENEVEIKSRTRARNTKERLNRERENTNHITKDILLISETEGERACYITPKRPRSCYITPKRPRSSAKESHYKSAVSKDFLTEGKASDRTSRQLLDHLPGLTDDEEWSEQELQKLHCAFTSLPKHKPGFWSDVAMAVGSRTADECQKKYTEEPQGQGSRKHGSKKKQANKVQNGEKDSADAKTIKITAKVGTLKRKRQMRDCLEHLAKDNHDDFFTATPLQKQRIQLPSFQYSQDDDFLLDMDRDPASPSSIITSPLRSTTPQCQHFSPSMLAAIERNNCDRYVYQMQKNAKKYGKSNGGLVWGNIRKKTVKTDLSSPPPTRKALFNKDLGKNTDISKYFIDDTESDEEEKDYYFSNSD
What is the function of this protein?
Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
What are the official names of this protein?
Mis18-binding protein 1, Kinetochore-associated protein KNL-2 homolog.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Note=Associated with centromeres in interphase cells, from late anaphase to the G1 phase. Not detected on centromeres during earlier phases of mitosis. Associated with chromatin.
Protein: MU133_SCHPO
Sequence: MEECKLDINKGKDAEILYEEYKYHEIKEMSFSSCARTSPELLKKFGCDAHVITSVEGAPKKENKKIWEFFKGSNKIKNLFTMFTCCFANDEEEIWGEETNESVVYKEYTYNSRWKIEIPSYPVREIPYVVADTPYNKLLCPLSSLEWVSKLILMDNANSIGMKNNRYSTNPFIYGMCYIIRNNANRILLESCYCENSTGMSTCPRILEFMPYEPLLKYNSYRLLSTYENSYKELSEMLTNNNAPLEVLIHHVMLYHYYPSFLQSALWTAVSSYLEERCNNGLYSKLLVKAAKQHFGDIRLYFVTPDDIYTFDHCNNWIAIVTRNFMAYIETKRKLEFDSIPFNCPLITQLFPLISSPKEMAWLLLIVCTDSNESWFPVHAYINTKTRILRPRSPKLDFFLKESDLLYFQDKQSISEFDIIRKDLLEDLIQCDSYVNTREQLRRRRETLNRKRITIAKLQNNHSQITFPYKRHNIHKSVDSIQFCKPASNLLTLKDNSYTQIPLEPLLLAEISV
What is the function of this protein?
Has a role in meiosis.
What are the official names of this protein?
Meiotically up-regulated gene 133 protein.
What is the protein family that this protein belongs to?
Belongs to the UPF0300 family.
What are the subcellular locations of this protein?
Golgi apparatus. Vacuole membrane.
Protein: SECA_PARL1
Sequence: MASLGAFAKRLFGSSNDRRIKAYKARVEAINALEPDMIALSDDALRGKTAEFRARLADGAVLDELLPEAFAVVREAAKRSLGQRHYDVQLIGGMVLNDGNIAEMKTGEGKTLVSTLAAYLNALTGKGVHVVTVNDYLAKRDADWMGQIFRFLGLEVGVVLHGLDDNQRRAAYAADITYGTNNEYGFDYLRDNMKYQLASMVQRGHGFAIVDEVDSILIDEARTPLIISGPLDDKSDLYLSIDEVIPEIGEEDYELDEKQRTVNLTEEGNERVEEILRNRGIMLEGNLYDIENISIVHHVNNALRAHKLFQKDKDYIVKTGKVVIIDEFTGRMMEGRRYSDGLHQALEAKERVPIQPENQTLASITFQNYFRMYEKLSGMTGTALTEASEFGDIYGLDVLEIPTNKPIARIDEDDEVYRTTREKYEAMIGEIEECASRGQPVLVGTTSIEKSETLSELLKKKKVKHKVLNARYHEQEAHIVAQAGVPGNVTIATNMAGRGTDIQLGGNLDMRLADETAGIENEAELARKTAEVKADIEAKKQRALEAGGLYVIGTERHESRRIDNQLRGRSGRQGDPGRSKFYLSLEDDLMRIFGTDRMDGMLQKLGLQEGEAIVHPWINKALEKAQQKVEARNFDIRKNLLKFDNVMNDQRRAIFEQRIELMRAEDVSDTVDDMRRQVIDDMVAAHVPEKAYAEQWDMAGLKEEVKKNLDLDLPIETWADEEGIAEEEIRERLYSASDRHMASKAAQVGPDLMRQVEKAVLLQTLDQHWREHLMMLDHLRQAVGLRGYAQRDPLNEYKSEAFELFESLLARLRENVTRQLSVAQFITEAPRIEEQPLPEMQAHHTNPLTGEDEMADGDVATMQRPMRNDPGVAADPNDPRTWGKTPRNAPCPCGSGKKYKHCHGAL
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: METK_PHALU
Sequence: MAETFLFTSESVNEGHPDKLCDQISDAVLDACLEQDPESKVACETCTKTNLVMVFGEITTKANVDYEKIVRDTCRNIGFISNDVGLDADNCKVLVNIEQQSPDIAQGVHGHLTKRPEEIGAGDQGHMFGYATDETPELMPLSHVLATKLGARLTEVRKNGTCSWLRPDGKTQVTVEYYNDKGAMVPVRVHTVLISTQHDETVTNDEIAADLKEHVIKPVIPEKYLDEKTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSIVASELARRCIVQVSYAIGVPEPLSVFVDTYGTGKIPDKEILKIVKENFDFRPGMISINLDLKRGGNSRFLKTAAYGHFGREDPDFTWEVVKPLKWEKA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.  The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, Methionine adenosyltransferase, MAT.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUT_CHLTA
Sequence: MKFFCKLESGSSLPEYATSGASGADVRANINEPIAILPGQRALIPTGISVEIPHGYEIQVRSRSGLASKYGVIVLQSPGTVDADYRGEIRVILANLGEATFIVEPGMRIAQLVVAKVEQVSFVETQEELTATARGTGGFGHTGEC
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.