PharMolix/UniProtQA huggingface dataset:
Protein: ILVC_RHIE6
Sequence: MRVYYDRDADLNLIKAKKVAVIGYGSQGRAHALNLKDSGAQNLVIALKAGSPTVKKAEADGFKVMTVAEAAGWADLMMMATPDELQADIYKADIAPNIRDGAAIAFAHGLNVHFGLIEPKASVDVVMIAPKGPGHTVRGEYQKGGGVPCLVAVHQNASGNALELALSYACGVGGGRSGIIETNFREECETDLFGEQVVLCGGLVELIRAGFETLTEAGYAPEMAYFECLHEVKLIVDLIYEGGIANMNYSISNTAEWGEYVTGPRIITEETKAEMKRVLKDIQTGKFTSEWMQEYRSGAARFKGIRRNNDSHQIEEVGAKLRGMMPWIGKNKLVDKSVN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: YOI9_SCHPO
Sequence: MENPSPTRTTNLQRIRSLYRLQEDKNNLNIPEPINGKVQEIDTKESLENVDRYGNYRSDFNVNNLGFYKVSKDPTLDKPNPAKRLGNKLIGHDDMLKYVDESIFMVVPGESHDRNEISAKELSRIQKWKSMCSIHLVSGNQLHSFRKTRKLILRTFKGIPDCWRSIAWWSFLVDSLPDKKLIDKYYQLNEQICDYDVQIDLDVPRTAATHFLFRKRYIGGQRLLFRVLHAVALYIPRVGYVQGMASIAATLLIYYPEEQAFIMMVNLLENRGMGDLFSSGFDTLLKAFDMLKHELSFTQSGRHLAEIGAEPSAFATRWYLTVFHQCVPFHTQLRIWDLLFLLGGSKGQTVRLLQATSLAVIQGMWDTLIDADFEVVMQALSGVIPIQNDNALLARIQLFWEKMPSENSSKSKRN
What are the official names of this protein?
TBC domain-containing protein C1778.09.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CCME_ECOSE
Sequence: MNIRRKNRLWIACAVLAGLALTIGLVLYALRSNIDLFYTPGEILYGKRETQQMPEVGQRLRVGGMVMPGSVQRDPNSLKVTFTIYDAEGSVDVSYEGILPDLFREGQGVVVQGELEKGNHILAKEVLAKHDENYTPPEVEKAMEANHRRPASVYKDPAS
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: KDPA_POLAQ
Sequence: MSTHAILTIVLYVGVLLLLAYPLGGFIDAVMSGQSITSKKPFRFIENFIYKVCGIDPAIEMSWLSYAIGLIAFNILGVLFVFGLQLFQGILPLNPQGLVSVSPDSSFNTAISFATNTNWQAYVGEGTMSYLTQMLGLTTQNFLSAASGIVVVIALIRGFARNSIKTIGNLWVDLTRITLYVLVPISVVYAIFLVGQGSIQNFDAYKDVKTVEVAKFDAPKLDADGQPLKDEKGAVLTGPASTDQQTLPMGPVASQEAIKMLGTNGGGFFNANSAHPYENPTPLSNFIQILSIFLIPAALCFTFGRMVRDKRQGWVVLVTMILIFLTVTFAAVHFESQANPVLTNLGVDGAMGNMEGKETRFGIDDSSIFASITTLASCGAVNSMHDSFMPMGGFVPLWNMMLGEVVFGGVGTGLYGMLVFAILAVFIAGLMIGRTPEYLGKKIESYEMKMVAIAILVTPILALVGTAIAVMSVDGVAGIANPGAHGFSEILYAFTSAANNNGSAFAGLSANTPFYNSMLAIAMWFGRFGVIVPVLALAGAFAAKKKIAVNEGTMPTHGPLFIVLLAGTVILVGALNYVPALALGPIVEQLMLPVIH
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ARGB_BACFR
Sequence: MKEKMKEKLTVIKVGGKIVEEEATLNQLLNDFAAIEGHKVLVHGGGRSATKIAAQLGIDSKMVNGRRITDAETLKVVTMVYGGLVNKNIVAGLQARGVNALGLTGADMNVIRSMKRPVKEVDYGFVGDVERVDSTLLSDLIHKGVVPVMAPLTHDGQGNMLNTNADTIAGETAKALSAIFDVTLVYCFEKKGVLRDENDDESVIPQINHAEFQRYIAEGVIQGGMIPKLENSFEAINAGVSEVVITLASAIHTDGGTRIKK
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSX_TERTT
Sequence: MSQQIHLSIDAMGGDQGPRLVIEASIAFLKRYPHTRLTLFGDFADLEAAVKGSVCASRMSLIQTEITVAADERAGSALRHKQGSSMWKAVELVATGQADACVSGGNTGALMAMGRKLIKTFPGVSRPAICKPIPTARGSSFILDLGANLNCSAQQLVQFALMGSALARVYGRENPSVALLNVGTELSKGSESILTAAALMREHPTINFAGFVEGHGLYQGEVDVVVCDGLIGNVALKVSEGVAAFIASSLKAKLRENRFNQIAGLIVEPLLRRWMAAYNPSNFNGAAMLGLQRTLVKSHGGTDKFGFEQALVAAVDQVSANIPERIAQCL
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: QUEC_RICCK
Sequence: MKKLVNLVSGGADSATVLAIAQKMGYEIYAMSFNYGQRNNAELRKVRELVKEYNVKQHKIVNIDLRAFSGSALTDNNISVPHYHDVNELPDDVPVTYVPARNTIFLSYALGFAEVIGAKDIFIGVHTSDSANYPDCRPEYIKSFEEMANLATNMGVQGKKITIHTPLIDMTKEQIIRTGLELGVDYKNTISCYEPTEDDLSCGTCLACMIRLDAFKKNDIQDPIKYV
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: ISDC_STAAC
Sequence: MKNILKVFNTTILALIIIIATFSNSANAADSGTLNYEVYKYNTNDTSIANDYFNKPAKYIKKNGKLYVQITVNHSHWITGMSIEGHKENIISKNTAKDERTSEFEVSKLNGKIDGKIDVYIDEKVNGKPFKYDHHYNITYKFNGPTDVAGANAPGKDDKNSASGSDKGSDGTTTGQSESNSSNKDKVENPQTNAGTPAYIYTIPVASLALLIAITLFVRKKSKGNVE
What is the function of this protein?
Involved in heme (porphyrin) scavenging.  Binds hemoglobin and almost exclusively free-base protoporphyrin IX.  Probably has a role as the central conduit of the isd heme uptake system, i. e.  mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF.  Hemin-free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor.  The reaction is reversible (By similarity).
What are the official names of this protein?
Iron-regulated surface determinant protein C, Staphylococcal iron-regulated protein D.
What is the protein family that this protein belongs to?
Belongs to the IsdC family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan- anchor. Note=Anchored to the cell wall by sortase B (By similarity).
Protein: THIG_RHOPT
Sequence: MVKFYDREFGSRLLIGSALYPSPAIMQDSIRESGAEIVTVSLRRETAGGKAGDQFWSLIRELGVTVLPNTAGCRGVRDAVTTAKLARELFATSWIKLEVIADNDTLQPDVVGLVEAAQILIKDGFEVFPYCTEDLSVALRLVDAGCRVIMPWAAPIGSARGITNRDALKLLRDRLPDITLVVDAGLGAPSHAAEAMELGYDAVLLNTAIAKAEDPVAMARGFKLAIEAGRTGFEAGLMGARDFASPSTPVIGTPFWHAVS
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAE_XANAC
Sequence: MSDFIVGLTGGIASGKSALAAEFEKLGVPVIDADVIARQVAEPGPILDAIAAYFGDSVLLPDGTLNRQALRYRVFADTAQRQALEAITHPAIRRELQRAALAAQGPYAIVAIPLLAEAGGRATYPWLDRILVVDVPVALQHERLMQRDGATAELADRMITAQATREKRLAIADEVVCNHGVLKQLSQAARRLDADYRARANP
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_ACAM1
Sequence: MPRPRKRFAQHWLKSQAVLRQIIAAAKIQGCDRILEIGPGRGVLTRELLAQAQSVVSVELDRDLCKSLRHTFNDQENFTLLELDFLNLDVAAELTEPLPNKVVANIPYNITSPILSKLLGRIDAPAQPVYETVVLLIQKEVADRLVAEPGSKIFNGLSVRSQYLADCELICPVPASAFKPAPKVESAVVRLTPRPYPQPVQNPQWLSTLLKVGFSSRRKMLRNNLKSLVDRDQLSECLNTLNISLQARAEDLSVTQWIALSDSVHPSQV
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_CAMHC
Sequence: MSDYYEILGVPKDADSDEIKKAFRKLALKYHPDRNAGDKEAEEKFKEINEAYQVLGNDERRQTYDRYGKEGLNGAFGNDFGGFDFGDIFDTFFGGGGFNKSRSQRYDDAYDLDSEILVSISFKDAFFGVSKDIKYKIKKPCKTCDGTGSKDKKLNTCPYCGGSGKIVKRSGFLSFAQTCPFCKGSGQIVKEKCHDCAGKGFIEEQVNVKFDIPKGVNTGIRIRIAKKGNISKSGEIGDLYVAVQVKDDKFFVRSADDIYIEVPVFFTQAILGKTIKVPTMHGEKELQLKVGSKDKDQFVIEKEGFENIRTKIAGNLIVQINVQTPKKLTDEQIELLEKLHESFDKTADGIFDKIKNWFK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURT_METVS
Sequence: MVGTPLFSNAKKILLLGSGELGKEVIIEAQRLGVECIAVDSYENAPAMQVAHRYHVIDMKDSGSLRAVIEREKPDLIVPEIEAINTDTLKEMETEGYHVVPTANAAKLTMDREGIRRLASEKLGLRTAKYEFADSLDELKEAVKRIGIPCIIKPIMSSSGKGQSTVKSEFDIEKSWDYAKSATRGIGTKVIVEEFVNFDYEITLLTARTAFGTKFCEPIGHIQIDGDYHESWQPHPMCSPTKAKAQEVAKKITDELGGYGIFGVELFIMDDEVIFSEVSPRPHDTGMVTMVTQKMSEFEIHVRSILGLPVNVDLSYPGASYVIKSEIYKWAPEYDIIEASKLKDTKIRLFGKPVAKIGRRMGVALSTAEDVSVARDTAKKAANIVKIK
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: Y1318_MYCBO
Sequence: MRMSAKAEYAVRAMVQLATAASGTVVKTDDLAAAQGIPPQFLVDILTNLRTDRLVRSHRGREGGYELARPGTEISIADVLRCIDGPLASVRDIGLGDLPYSGPTTALTDVWRALRASMRSVLEETTLADVAGGALPEHVAQLADDYRAQESTRHGASRHGD
What are the official names of this protein?
Putative HTH-type transcriptional regulator Mb1318.
Protein: LPLA_YERPG
Sequence: MSSLRLLISDSYDPWFNLAVEECIFRQMSPNQRVLFLWRNADTVVIGRAQNPWKECNTRRMEQDGVKLARRSSGGGAVFHDLGNTCFTFMAGKPGYDKTISTQIILNALASLGIQATASGRNDLVVINGEDERKVSGSAYKETKDRGFHHGTLLLNADLSRLADYLNPDPKKLQAKGITSVRSRVTNLVELLPGIDHGKIRTAIEQAFFAYYDEQVSAEVISPQSLPNLPGFTEQFAKQSSWEWNFGQAPAFSHVVDTRFIWGGIELHFDVLHGAIDRCQIFTDSLNPTPLEALAQRLQGAAYRPDAIDKICQHWIDDFPELQTELQQACHWLVEVLR
What is the function of this protein?
Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.
What are the official names of this protein?
Lipoate-protein ligase A, Lipoate--protein ligase.
What is the protein family that this protein belongs to?
Belongs to the LplA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS1_STAAC
Sequence: MTEEFNESMINDIKEGDKVTGEVQQVEDKQVVVHINGGKFNGIIPISQLSTHHIDSPSEVVKEGDEVEAYVTKVEFDEENETGAYILSRRQLETEKSYSYLQEKLDNNEIIEAKVTEVVKGGLVVDVGQRGFVPASLISTDFIEDFSVFDGQTIRIKVEELDPENNRVILSRKAVEQEENDAKKDQLLQSLNEGDVIDGKVARLTQFGAFIDIGGVDGLVHVSELSHEHVQTPEEVVSIGQDVKVKIKSIDRDTERISLSIKDTLPTPFENIKGQFHENDVIEGVVVRLANFGAFVEIAPGVQGLVHISEIAHKHIGTPGEVLEPGQQVNVKILGIDEENERVSLSIKATLPNEDVVESDPSTTKAYLENEEEDNPTIGDMIGDKLKNLKL
What is the function of this protein?
Binds mRNA; thus facilitating recognition of the initiation point.  It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity).
What are the official names of this protein?
30S ribosomal protein S1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS1 family.
Protein: MNHC1_STAAC
Sequence: MEIIMIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANLFLITMGGLKHGTVPIYEANVKSYVDPIPQALILTAIVIAFATTAFFLVLAFRTYKELGTDNVESMKGVPEDD
What is the function of this protein?
Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.
What are the official names of this protein?
Na(+)/H(+) antiporter subunit C1, Mnh complex subunit C1.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PTN_CHICK
Sequence: MPQQQQQRRMFTAALLALVFILAAVSTTEAGKKEKPEKKAKKSDCGEWQWSVCVPTNGDCGLGTREGTRTGAECKQTTKTQKCKIPCNWKKQFGAECKYQFQAWGECDLNTALKTRTGNLKRALHNADCQKTVTISKPCGKLTKPKPQESKKKKKEGKKQEKMLD
What is the function of this protein?
Secreted growth factor that mediates its signal through cell-surface proteoglycan and non-proteoglycan receptors (By similarity).  Binds cell-surface proteoglycan receptor via their chondroitin sulfate (CS) groups (By similarity).  Thereby regulates many processes like cell proliferation, cell survival, cell growth, cell differentiation and cell migration (By similarity).
What are the official names of this protein?
Pleiotrophin, PTN, Heparin-binding brain mitogen, HBBM, Heparin-binding growth factor 8, HBGF-8, Heparin-binding growth-associated molecule, HB-GAM, Heparin-binding neutrophic factor, HBNF, Osteoblast-specific factor 1, OSF-1.
What is the protein family that this protein belongs to?
Belongs to the pleiotrophin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ANXA5_CYNPY
Sequence: MACLKGAKGTVQDAPDFNDKEDAETLRHAMKGLGTDEDTILKLLISRSNKQRQQIALTYKTLFGRDLTDDLKSELSGKFETLLVALMVPAHLYDACELRNAIKGLGTLENVIIEIMASRTAAEVKNIKETYKKEFDSDLEKDIVGDTSGNFERLLVSLVQANRDPVGKVDEGQVENDAKALFDAGENKWGTDEETFISILSTRGVGHLRKVFDQYMTISGYQIEESIQSETGGHFEKLLLAVVKSIRSIQGYLAEVLYNSMKGAGTDDQTLIRVLVSRSEIDLFNIRQTFRKHYGKSLHAMIQSDTSGDYRNALLLLCGEIDD
What is the function of this protein?
Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis.
What are the official names of this protein?
Annexin A5, Annexin V, Annexin-5.
What is the protein family that this protein belongs to?
Belongs to the annexin family.
Protein: GMHBB_NEIMB
Sequence: MKLIILDRDGVINQDRDDFVKSVDEWIPVEGSMDAVAFLTQAGYTVAVATNQSGIGRKYFTVQNLTEMHAKMHRLVRQAGGEINGIWFCPHTDADNCNCRKPKPGMIEDIIGRFNAQASETWLVGDSLRDLQAIDAVGGKPALVLTGKGKKTLSQHGHELPEHTQVFDTLLDFSQYIMQENTAPQAD
What is the function of this protein?
Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position.
What are the official names of this protein?
D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase, D,D-heptose 1,7-bisphosphate phosphatase, HBP phosphatase.
What is the protein family that this protein belongs to?
Belongs to the GmhB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURE_PSEAB
Sequence: MRILIANDDGVTAPGIAALYDALADHADCVVIAPDQDKSGASSSLTLDRPLHPQRLDNGFISLNGTPTDCVHLGLNGLLEELPDMVVSGINLGANLGDDVLYSGTVAAAIEGRFLKGPAFAFSLVSRLTDNLPTAMHFARLLVSAHERLAVPPRTVLNVNIPNLPLDRVRGIQLTRLGHRARAAAPVKVVNPRGKEGYWIAAAGDAEDGGPGTDFHAVMQGYVSITPLQLDRTFHEAFGGLDEWLGGLT
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CP270_RAT
Sequence: MALFIFLGIWLSCLVFLFLWNQHHVRRKLPPGPTPLPIFGNILQVGVKNISKSMCMLAKEYGPVFTMYLGMKPTVVLYGYEVLKEALIDRGEEFSDKMHSSMLSKVSQGLGIVFSNGEIWKQTRRFSLMVLRSMGMGKRTIENRIQEEVVYLLEALRKTNGSPCDPSFLLACVPCNVISSVIFQHRFDYSDEKFQKFIENFHTKIEILASPWAQLCSAYPVLYYLPGIHNKFLKDVTEQKKFILMEINRHRASLNLSNPQDFIDYFLIKMEKEKHNEKSEFTMDNLIVTIGDLFGAGTETTSSTIKYGLLLLLKYPEVTAKIQEEITRVIGRHRRPCMQDRNHMPYTDAVLHEIQRYIDFVPIPLPRKTTQDVEFRGYHIPKGTSVMACLTSALHDDKEFPNPEKFDPGHFLDEKGNFKKSDYFMAFSAGRRACIGEGLARMEMFLILTSILQHFTLKPLVNPEDIDTTPVQPGLLSVPPPFELCFIPV
What is the function of this protein?
A cytochrome P450 monooxygenase involved in muricholic acid (MCA) synthesis.  Hydroxylates at the 6-beta position two major bile acids, chenodeoxycholic acid (CDCA) and ursodeoxycholic acid (UDCA) to form alpha-MCA and beta-MCA, respectively.  May regulate NR1H4/farnesoid X receptor signaling, as taurine-conjugated MCAs are antagonists of NR1H4.  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).
What are the official names of this protein?
Cytochrome P450 2C70, CYPIIC70, Cytochrome P-450Md, Cytochrome P450 P49.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: DDL_STAEQ
Sequence: MTKENICIVFGGKSAEHDVSILTAQNVLNAIDKERYQVDIIYITNDGEWKKKDNITQEIKNTDELVINDVETGEISQLLSKGSLGKSYDAVFPLLHGPNGEDGTIQGLFEVLDIPYVGNGVLAASSSMDKLVMKQLFEHRGLPQLPYISFLRSEYEKYENNIIKLVNDKLTYPVFVKPANLGSSVGISKCNNEEELKSGIAEAFQFDRKLVIEQGINAREIEVAVLGNDYPETTWPGEVVKDVAFYDYKSKYKDGKIRLDIPADLDQDVQMTLRNMALEAFKATDCSGLVRADFFVTDDNQIYINETNAMPGFTAYSMYPNLWKNMGLSYPDLIAKLIDLAKERYEDKKKNKYKIDY
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PE11_LITPE
Sequence: QPWLPFG
What is the function of this protein?
Induces contraction of intestinal smooth muscle in isolated guinea pig ileum.
What are the official names of this protein?
Peroniin-1.1.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Peroniin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: FABG3_BRANA
Sequence: MATTVAATKLTSLKAVKKLGFREIRQVRQWTPLQSSMPHFGSRQSFATSTVVKAQATAVEQSTGEAVPKVESPVVVVTGASRGIGKAIALSLGKAGCKVLVNYARSAKEAEEVSKQIEAYGGQAITFGGDVSKEADVEAMMKTAIDAWGTIDVVVNNAGITRDTLLIRMKKSQWDEVIDLNLTGVFLCTQAATKIMMKKRKGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTAAREGASRNINVNVVCPGFIASDMTAKLGEDMEKKILGTIPLGRYGQPEDVAGLVEFLALSPAASYITGQAFTIDGGIAI
What are the official names of this protein?
3-oxoacyl-[acyl-carrier-protein] reductase 3, chloroplastic, 3-ketoacyl-acyl carrier protein reductase 3.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Plastid, chloroplast. Plastid. Note=And non-photosynthetic plastids.
Protein: RS15_PAEAT
Sequence: MALDAAVKQSIIKEYATTEGDTGSPEVQVAVLTQRIKDLTEHMKEHKHDFHTQRGLLAMVGRRKRMLSYLKNTDIARYRALIERLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: BORE1_CHICK
Sequence: MAPARRKAAAGARGRKLSAFLKDFDREVRSRVEQLRTNGERLVKEMENLYDVELLRLPAALREMNWLEFFAKGGSQKVVEEAVTADLGITEINKLTAELIQTPLKIVTKEKSKQGIEATEEAAEVPLLPPAKKAKHDSQLLLEQAAASTNPRNGKVRTSTKKAPVSRSRRAPSARVKRVSKRSSKSSFITPATGRNLDLCARGGASIVTPRFDSRVFKTPGLRTPAVNERVYTISANGSPLADGMMSSLPFLLGGGESIRLTASDLTKKNLLHLNPEGRGIMQKLSVRLCTSLYSAKT
What is the function of this protein?
Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis.  The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly (By similarity).
What are the official names of this protein?
Borealin, Cell division cycle-associated protein 8, Dasra-B, GgDasraB.
What is the protein family that this protein belongs to?
Belongs to the borealin family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Note=Localizes on chromosome arms and inner centromeres from prophase through metaphase and then transferring to the spindle midzone and midbody from anaphase through cytokinesis.
Protein: FMTA_STAA8
Sequence: MKFNKVKLVIHACVLLFIIISIALIFHRLQTKTHSIDPIHKETKLSDNEKYLVDRNKEKVAPSKLKEVYNSKDPKYKKIDKYLQSSLFNGSVAIYENGKLKMSKGYGYQDFEKGIKNTPNTMFLIGSAQKFSTGLLLKQLEEEHKININDPVSKYLPWFKTSKPIPLKDLMLHQSGLYKYKSSKDYKNLDQAVKAIQKRGIDPKKYKKHMYNDGNYLVLAKVIEEVTGKSYAENYYTKIGDPLKLQHTAFYDEQPFKKYLAKGYAYNSTGLSFLRPNILDQYYGAGNLYMTPTDMGKLITQIQQYKLFSPKITNPLLHEFGTKKYPDEYRYGFYAKPTLNRLNGGFFGQVFTVYYNDKYVVVLALNVKGNNEVRIKHIYNDILKQNKPYNTKGVIVQ
What is the function of this protein?
Catalyzes the liberation of D-alanyl moieties present on wall teichoic acid (WTA) and lipoteichoic acid (LTA) (By similarity).  Affects the methicillin resistance level and autolysis in the presence of Triton X-100 as well as the cell wall structure (PubMed:9371333, PubMed:10471551).
What are the official names of this protein?
Teichoic acid D-alanine hydrolase, Teichoic acid D-alanine esterase.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.