PharMolix/UniProtQA huggingface dataset:
Protein: GABT_MYCTO
Sequence: MASLQQSRRLVTEIPGPASQALTHRRAAAVSSGVGVTLPVFVARAGGGIVEDVDGNRLIDLGSGIAVTTIGNSSPRVVDAVRTQVAEFTHTCFMVTPYEGYVAVAEQLNRITPGSGPKRSVLFNSGAEAVENAVKIARSYTGKPAVVAFDHAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPLSYPYRDGLLDKQLATNGELAAARAIGVIDKQVGANNLAALVIEPIQGEGGFIVPAEGFLPALLDWCRKNHVVFIADEVQTGFARTGAMFACEHEGPDGLEPDLICTAKGIADGLPLSAVTGRAEIMNAPHVGGLGGTFGGNPVACAAALATIATIESDGLIERARQIERLVTDRLTTLQAVDDRIGDVRGRGAMIAVELVKSGTTEPDAGLTERLATAAHAAGVIILTCGMFGNIIRLLPPLTIGDELLSEGLDIVCAILADL
What are the official names of this protein?
4-aminobutyrate aminotransferase, (S)-3-amino-2-methylpropionate transaminase, GABA aminotransferase, GABA-AT, Gamma-amino-N-butyrate transaminase, GABA transaminase, Glutamate:succinic semialdehyde transaminase, L-AIBAT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
Protein: PRR9_HUMAN
Sequence: MSFSEQQCKQPCVPPPCLPKTQEQCQAKAEEVCLPTCQHPCQDKCLVQAQEVCLSQCQESSQEKCPQQGQEPYLPPCQDQCPPQCAEPCQELFQTKCVEVCPQKVQEKCSSPGKGK
What are the official names of this protein?
Proline-rich protein 9.
Protein: Y130_NITEU
Sequence: MLKWAIIFAIISFISGVFGFRSTSAGTASIAKFLFFLFALITLVLLVLGLLGIGVVA
What are the official names of this protein?
UPF0391 membrane protein NE0130.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: A2MGH_PSEAE
Sequence: MSNLRRFSRSLAVAALVLLPFAAVQAEDTVEPSGYTPMAGESFFLLADSSFATDEEARVRLEAPGRDYRRYRMEPYGGVDVRLYRIEQPLEFLKRQKNLHRVLAEGQFKGEGLSNTLAYLWDNWYRKSRRVMQRAFSYESRQQVTEAVPELKMGNAMTAPTPYDAQPQYAPIPGLPLVSQFRYPLWDAKPIEPPQDVKLAGSSSEFINVVPGNVYIPLGKLKPGLYLVEALVGKYRATTVVFVSNSVAVSKVAGDELLVWTARKHEGTPVPDTKVLWTDGLGVMSSGNTDADGLLRLKHASPERSYVIGEDREGGVFVSENFYYDSEIYDTKIYAFTDRPLYRPGDWVSLKMVGREFKDARQSQAAASAPVRLSVIDASGTVLQSLDLRFDAKSGANGRFQLPENAVAGGYELRFDYRGQTYSSAFRVAEYIKPHFEVALDLAKPDFKTAEPVKGEIVLLYPDGKPVANARLQLSLRAQQLSMVDNELQYLGQFPVELSSTELTTDGKGRAAIELPPAEKPSRYMLTIFASDGAAYRVKTSKEILIERGAARYRLSAPQRFSAAGEKVEFSYASEQPTPLKPSSYQWIRLEDRATDSGPVADGRFALTFERPGTYSVELRDDKGQLLGATGHSVSGEGVKSVPGTVEVVFDKPEYRTGEEASALITFPEPVEDALLSLERDKVEATALLSKGADWLRLEKLNPTQYRVWIPVREEFSPNLTFSVLYTKGGDYSFQNAGIKVGMPQVEIDIATDKERYEPGETVTVTLATRFAGKPVSSHLTVSVVDEMVYALQAEIAPGIDQFFYHPRRNNVRTSASLAFISYDVALPGSTSAPGRANRSERGVKVLERPRREDVDTAAWQPELVTDAQGKASFSFRMPDSLTRWRITARAIDDNGQVGQKKQFLRSEKPLYLKWSGPTRFRQGDQPDLGLFVFNQGEQPVKAELLSGPPGSQRSQTLELAKGVNYIPLAQQPLSDGDWSAELRQDGQVRDRLAVRFNLLADGWQVEQMQNLSLAAASNPLQLPADARDVRLRLADGPAAAYLGNLDDLLEYPYGGVEQTASQLLPLSIAYPALAGGEPRIRDRLRLIMQNSRLRLVQMAGPDAWFAWWGGDVDGDAFLTAYAYYADWYASRALEIQLPAEHWQRILEPYAKQATQTPLLQRALILAFARDMQLPVNTLLGGLLNDLANAGEGQARAEPLEADDGLVLGDPDSAVGLAAARVLAVDLARQLRVAVPAPLAAQAETATQRLREAGLPFTDALLASRSAVDGQQASALLQRLAPAQSTLERALALTWLQGALAQAPQGKLPQPPKDWQAQRGASGETYWQWRGRGIPSWVDLDEAPARPLPVALSYRSAQAPSGQLPVQISRRLLRLVPGEGAFEFKVEEVGDKPLSSDELYLDEVTLNVPEDTALRYGMLELPLPPGADVERTTWGIKISGLAGDEATTLERARNEPGELFYGVPVDSLSGEQRFRHLVRFSQKGSFNLPPARYLRLYAPEQQALEAKPALAKVKVE
What are the official names of this protein?
Alpha-2-macroglobulin homolog.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.
Protein: TRUA_PYRHO
Sequence: MKVALKIAYDGTKFHGFQRQPNVRTVEGEIIKALNNSGIMFNELKSASRTDKGVSALGNVVAITTEDERITNPMILNAKLKDVWVLSAVKVPSDFHPRFWARSKVYRYYLPSFDLDVEKVKECSKLFLGVHDFSAFSRVDGRETVRSIDRIEVLDLGPVLAIEVEAKSFLWEMVRRIVKTLELCGLGKLSSEEVRKMLRGKFEKSRKVPPAPAEGLLLVEVKYKGIEFPIHDKALEKFRKDMEKRFREKIARAYLLWDMTKI
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: SRP54_AQUAE
Sequence: MLELLTEKFSHALEKLTNARKITEKNINQTLREIRLALLEADVDYQVAKDFIKRIREKVVGKEVPKNLSPAEFVIKTVYEELVDILGGEKADLKKGTVLFVGLQGTGKTTTIGKIANLLKKGGHKVAVSSTDLRRPAAMLQLQRLAERVGVPYYEFEEGLGAVEIARRAVKRAKEESVDYLLLDTAGRLHVDEELMKELQEIKEVTNPSEILYVADAMQGQTALETAKTFHERLGLTGVVITKMDGDARGGLALSVKEVLGVPIKFIGVGEKIEDIEPFYPDRIAQRILGLGDIQSLVEKAQEVITEDKAQVMATKVMTGEFDLEDLREMLRMIQQMGPLDKLLSMIPGVAPQLKHLKVDEKQFKKIEAIINSMTPEERRNPKIINMSRKKRIARGSGTTVSDVNKLLKRYEEMKKMMRKLQKAGGMPAIPKMPKMPRFPSEASSFNLFLFLST
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes.  The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
What are the official names of this protein?
Signal recognition particle protein, Fifty-four homolog.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. SRP54 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=The SRP-RNC complex is targeted to the cytoplasmic membrane.
Protein: RSGA2_VIBPA
Sequence: MNQTHTFCDTLISTSNPLKQLGWKPFFQQQLTLDDYDNTIFARVIAHHRSGYLLATEAGQVHLNVHHSLPNMTVGDWVILNEDQQFVRLLDRLSLFSRKAAGSKVAEQLIAANVDTVFIVCSLNHDFNLSRIERYLALVHEADVEPVIVLSKADLCDDVDELKSQVQKLDPLLVIETVNGLDAESTSKLMSWCNEGQTVAFIGSSGVGKSTLVNALLGQQEQSTGHIREDDSKGRHTTTSRSIHLLPAGGILIDTPGMREIQLVDCEAGVSEAFADVEALADHCRFGDCKHQTEPGCAVQAAIENGSLEVRRFNNYQKLLREQAFNGATLAEQRAQSRQFGKLTRNVMSDKRKRQQSY
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLO2_SHIF8
Sequence: MNLNSIPAFDDNYIWVLNDEAGRCLIVDPGDAEPVLNAITANNWQPEAIFLTHHHHDHVGGVKELVEKFPQIVVYGPQETQDKGTTQVVKDGETAFVLGHEFSVITTPGHTLGHICYFSKPYLFCGDTLFSGGCGRLFEGTALQMYQSLKKLSALPDDTLVCCAHEYTLSNMKFALSIFPHDLSINDYYRKVKELRAKNQITLPVILKNERQINVFLRTEDIDLINGINEETLLQQPEERFAWLRSKKDRF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: YJOB_BACSU
Sequence: MTNIPFIYQYEEKENERAAAGYGTFGYLITRIEETLYDQYGVFYELYASDDPNTEYWELLVEDVRSGSLEPEHVAYIFEKLEKKTFAYDEDEKEPDYTVHKSIRNSVYAYPEKGVAFARIPYFQDGSIMSFDCLFAVNDEKMRAFLEGVRPRLWEKSKRKVTVFTDGDGGTSREQEAIVREVQRSQVIMNPLLKKEIYRSIDQFFHSDKSFYQTYDIPYKRGILLYGPPGNGKTTLVKSIAGSIDAPVAYWQITEFTSSETIEEVFQAARRLAPAVLVIEDIDSMPEDVRSFFLNTLDGATSKEGLFLIGTTNYPEEIDPGLMNRAGRFDRAYEIGLPDEELRLEYMKMRGFGIFLSEGEIKNAAKLTEGFSFAQLGELYVSSALQWHQEGNHHIETMVKDMTGEQRKSQRGSWMERNKVGFH
What is the function of this protein?
Shows ATPase activity.
What are the official names of this protein?
Uncharacterized ATPase YjoB.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEGPH_PLAF7
Sequence: MDIIFCTPTYCKIMLMIIMLISLRTRCDTNNFLNCSVEKEEGEEEIISTNLKRINDDMNILGRILNDERNIKITDIVEMLQNEYDDKKKKKKKKKYIYRKKKSNNKINEINSVQHFNVKENILNEKKKNPLNDNFKNPKLRKHSPNNKKNKNKIGQIKFHIVGYDKKKITKYLTPSMISSIQKRLMNKNKKTNVNVNMSNGRVLPFFPKEYFLHSSTHEKKDKMATKKNNKEESIINERLLENLENISLSRTIKDIRGEEGNERKVKEEDNNIKEEGNSFKKYFKGVVKLYVDITEPNLEMIWQNYPPKSITGSGFIIEGHLIITNAHNISYSTRILIRKHGNSGKYEAKILYVAHDVDIAILTTDDKTFFDDVYALHFGALPSLKDEIITIGYPAGGDKLSVTEGIVSRIDVQYYKHSNYKFLLTQIDAPLNPGNSGGPALVRGKVVGICFQSYKVSNNISYIIPSTIISHFLLDIHKNKDYTGYAFLGVKYEPLENPSLREALGLEEMERKKIIKKNVGILITEVFEGHMSKQDDKYHDMDNKHHNVGDTHHNVGDTHHNVGDDHTDNLQGDTDYCTYILNSNIITSDKKNIYSDKKKKKIYSDNNNNNNNFNYYYNMHGEDEQSCYGLKKNDIILRVDGKDINNDGSVILRDNETVGFQHLFNEKFINDLCIIKIVRNKKIKSVMVKLYKVKYLLNQHNWDKRNKYFIYGGIVFSILTRSLYVYTQNPEINKLMLYNNFKKKSKDEIVVLKNILPTKITTGYYYTDSIVLRVNNIKVKNLKHLIELIEMTKYTNRLMYLKNNKHTLQSYINYYNTKITSLNINTIIHILILTTSGQKVPIVLNKRDVEKYNEEIKKIYSITRDRYVY
What is the function of this protein?
Serine protease which also acts as a protein chaperone (PubMed:24494818).  Plays a role in the parasite development in host erythrocytes possibly by protecting it against thermal and oxidative stresses (PubMed:24494818).
What are the official names of this protein?
Serine protease DegP homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1C family.
What are the subcellular locations of this protein?
Cytoplasm. Parasitophorous vacuole. Host cell membrane; Peripheral membrane protein. Host cytoplasm. Note=Localizes to the cytoplasm and cell membrane of host erythrocytes.
Protein: MUTH_YERPY
Sequence: MSVYSLPPAPPSDEHQLFQRAQALSGFTLGELATRAQWVIPADLKRVKGWVGMLLEFYLGASAGSKPEQDFADIGIELKTIPISAQGKPLETTFVCVAPLTGNSGVTWESSHVRHKLARVLWVPVEGERHIPLAERRVGAPLLWSPNVEEEELLRRDWEELMDLIVLGKVESITARHGQVLQLRPKAANSRALTEAIGEFGQPIMTLPRGFYLKKTLTAPMLARHFLL
What is the function of this protein?
Sequence-specific endonuclease that cleaves unmethylated GATC sequences.  It is involved in DNA mismatch repair.
What are the official names of this protein?
DNA mismatch repair protein MutH, Methyl-directed mismatch repair protein.
What is the protein family that this protein belongs to?
Belongs to the MutH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS251_ARATH
Sequence: MAPKKDKVPPPSSKPAKSGGGKQKKKKWSKGKQKEKVNNMVLFDQATYDKLMSEAPKFKLITPSILSDRLRINGSLARKAIRDLMVKGTIRMVSTHSSQQINTRATCLT
What are the official names of this protein?
40S ribosomal protein S25-1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS25 family.
Protein: RL403_CHLRE
Sequence: MQIFVKTLTGKTITLEVESSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGIIEPSLQALARKYNQEKMICRKCYARLHPRAKNCRKKSCGHTNQLRPKKKLK
What is the function of this protein?
Component of the 60S subunit of the ribosome.
What are the official names of this protein?
Ubiquitin-60S ribosomal protein L40.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
What are the subcellular locations of this protein?
[Ubiquitin]: Cytoplasm. Nucleus. SUBCELLULAR LOCATION: [60S ribosomal protein L40]: Cytoplasm.
Protein: CRCB_SALDC
Sequence: MLQLLLAVFIGGGTGSVARWMLSMRFNPLHQAIPIGTLTANLLGAFIIGMGFAWFNRMTHIDPMWKVLITTGFCGGLTTFSTFSAEVVFLLQEGRFGWALLNVLINLLGSFAMTALAFWLFSAAAAR
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PETN_TRICV
Sequence: MDIISLGWAGLMTMFTFSLALVVWARNGF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 8, Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PetN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: LSHB_MACFA
Sequence: MEMLQGLLLWLLLSMGGARASREPLRPLCRPINATLAAEKEACPVCITVNTSICAGYCPTMMRVLQAALLPLPQVVCTYHEVRFDSIQLPGCLPGVDPVVSFPVALSCRCGPCHRSTSDCGGPKDHPLTCDHPQLPGLLFL
What is the function of this protein?
Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids.
What are the official names of this protein?
Lutropin subunit beta, Lutropin beta chain, Luteinizing hormone subunit beta, LH-B, LSH-B, LSH-beta.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: TI214_LIRTU
Sequence: MILKSFLLGNLLSLCMKIINSVVGVGLYYGFLTTFSIGPSYLFLLRARVMEEGTEKEVSATTGFITGQLMMFISIYYAPLHLALDRPHTITVLVLPYLLFHFFWNNHKHFFDYGSTTRNSMRNLSIQCVFLNNLIFQLFNHFILPSSTLARLVNIYMFRCNNKMLFVTSSFVGWLIGHIFFMKWVGLVLFWIRQNHSIRSNVLIRSNKYLVSELRNSMARIFSILLFITCVYYLGRIPSPIVTKKLKETSETEERGESAEETDVEIETTSETKGTKQEQEASTEEDPSLCSEEKEDPDKLDGNQGYQENWKLEILKDKDLFWFEKPLVTLLFDYKRWNRPLRYIKNDRFEKTVRNEMSQYFFHTCPSDGKKRISFTYPPSLSTFGEIIQRKMSLYTTDKLLSPEDPYNHWVYTNEQKRHNLSNEFINRIEALDRGTLTLDVLEKSTRLCNNENEQEFFPKIYDPFLNGPYRGTTKKVYSRSIMDDSITWTEDSIEMVWINKIHDIFPNDYREFEQKMDLFNGESLSTDIGHSLTSINKFAGESAPNLNLKGLALLAEQRRLDSENQTKCLKFLSDVVTTDPNDQTIQNKYIGIEEIGKKVPRWSYKLTDHLEEQEKENEEESTEDHGIRSRKAKRVVIYTDNDQNTNTYTSTSTNSDQAEELALIRYSQQSDFRRDLIKGSMRAQRRKTVTWEMFQANVHSPLFLDRIDKTFFFSFDISGMMNLIFRNWVGKGPEFKTSDSEEKEAKEKEKTKEEKKEENERIAIAETWDTIIFAQAIRGSMLVTQSILRKYIVLPSLIIAKNLGRMLLFQFPEWYEDWKEWNREMHVKCTYNGVQLSETEFPKDWLTDGIQIKILFPFCLKPWHRSKLRSHHRDRMKKKGKKENFCFLTVWGMETELPFGSSRKRPSFFEPICKELEKKIRKVKKKCFLVLRALGERTKWFLRVLKEKTRWILKTVLFIKRIIKEFAKVNPILLFGLRKVYEPNENRKDSITNNKINHESIIRIRSVDWTNYSLTEKKMKDLADRTTTIRNKIERITKDKRKIFLTPDIKISPNETGCDDKRSESQKHIWQISKRRSARLIRKWHYFMKSFIERIYMDIFLCTINIPRRNAHLFLESTKKIIDKDIYNDERNKEGIDETNQNAIHFISTIKKSLSNISNNKSQIYCDLSSLSQAYVFYNLLQIQVINKYYLRFVLQYRGAYLFLKDRIKDHFGTRGILDAKSRPKKPPNSGMNEWKNWLRGHYQYNLSQTRWSRLVPQKWRNRVNQRRTIQNKDSKKDSYEKDQFIHYEKQNNYVVNSLPNKKEKFKKHYRYDLLSHKYIHYEDRKDSYIYGSPLQVNVNGDREIPYNYNTPKPESFYVPRGIAISDYLGEESIIDTGKNPDRKYLEWRILNFFLRKNIDIETWIDIDTGTNINKNAKTGTNDYQIIDKKDLFYLPIHQEINPSNQKQGFFFDWMGMNEEMLYRPISNLEPWFFSEFVLLYDAYKIKPWIIPIKLLIFNLNGNENISENKNINRNQKKDLRLSSNQKEYLELENRNQEEKEQLGQGNLGSDPRNRQKDLEKDYAESDIKKRRKKRQSKSNKEAELNFFLKRYLLFQLRWDDPLNQRMINNIKVYCLLLRLINPKEIAISSIQRGEMRLDVMLIQKDLTLTELIKRGILIIEPVRLSIKWDGQWIMYQTIGISLVHKNKYQTNRICREKKYVDENSFDRSIAQHGKVLVNGDENNYALLVPENIPSPRRRRELRILICLNSENGNVVDRNSVFFNGNNVRNCVQFLDEDKHFDTDINKFIQFKLFLCPNYRLEDLACMNRYWFDTNNGSRFSMSRIHMYPRFRIS
What is the function of this protein?
Involved in protein precursor import into chloroplasts.  May be part of an intermediate translocation complex acting as a protein-conducting channel at the inner envelope.
What are the official names of this protein?
Protein TIC 214, Translocon at the inner envelope membrane of chloroplasts 214, AtTIC214.
What is the protein family that this protein belongs to?
Belongs to the TIC214 family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: PKDCC_MOUSE
Sequence: MRRRRAAVAAGFCASFLLGSVLNVLFAPGSEPPRPGQSPGSSAAPGPGRRGGRGELARQIRERYEEVQRYSRGGPGPGAGRPERRRLMDLAPGGPGLQRPRPPRVRSPPDGAPGWPPAPGPGSPGPGPRLGCAALRNVSGAQYVGSGYTKAVYRVRLPGGAAVALKAVDFSGHDLGSCVREFGARRGCYRLAAHKLLKEMVLLERLRHPNVLQLYGYCYQDSEGIPDTLTTITELGAPVEMIQLLQTSWEDRFRICLSLGRLLHHLAHSPLGSVTLLDFRPRQFVLVNGELKVTDLDDARVEETPCTSSADCTLEFPARNFSLPCSAQGWCEGMNEKRNLYNAYRFFFTYLLPHSAPPSLRPLLDSIVNATGELAWGVDETLAQLETALHLFRSGQYLQNSTSSRAEYQRIPDSAITQEDYRCWPSYHHGGCLLSVFNLAEAIDVCESHAQCRAFVVTNQTTWTGRKLVFFKTGWNQVVPDAGKTTYVKAPG
What is the function of this protein?
Secreted tyrosine-protein kinase that mediates phosphorylation of extracellular proteins and endogenous proteins in the secretory pathway, which is essential for patterning at organogenesis stages.  Mediates phosphorylation of MMP1, MMP13, MMP14, MMP19 and ERP29 (PubMed:25171405).  May also have serine/threonine protein kinase activity (PubMed:25171405).  Required for longitudinal bone growth through regulation of chondrocyte differentiation (PubMed:19097194, PubMed:23792766).  May be indirectly involved in protein transport from the Golgi apparatus to the plasma membrane (PubMed:19465597).  Probably plays a role in platelets: rapidly and quantitatively secreted from platelets in response to stimulation of platelet degranulation (PubMed:25171405).
What are the official names of this protein?
Extracellular tyrosine-protein kinase PKDCC, Protein kinase domain-containing protein, cytoplasmic, Protein kinase-like protein SgK493, Sugen kinase 493, Vertebrate lonesome kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily.
What are the subcellular locations of this protein?
Secreted. Golgi apparatus. Note=Both secreted and present in the Golgi apparatus.
Protein: DPO3_STAEQ
Sequence: MAMTNREKFKVLADQIKISNQLEQDILEQGELTRIDVSNKNRTWTFQISLPHFLSHEDYLLFTHAIEEEFKEIATVAIDFSIKDTNNQDEFALKYFGHCIDQTRLSPKVKGQLKQKKLIMSGNVLKVLVSNDIERNHFDKACNGSLVKAFRQCGFEIDKVVFETDSTNHDDDLASLEAHIQQEDEQSAREATEKLEKMKAEKAKQQDNNESTVEKCQIGKPIQIENIKPIESIIEEEFKVAIEGVIFDINLKELKSGRHIVELKVTDYTDSLVLKMFTRKNKDDLDHFKALSVGKWVRAQGRIEEDTFVRDLVMMMSDIEEIKKTPKQDKAEDKRVEFHLHTSMSQMDGIPNISAYVEQAAKWGHQALAVTDHNVVQAFPDAHNAAEKHGIKMIYGMEGMLVDDGVPIAYKPTDRNLKDATYVVFDVETTGLSNQYDKIIELAAVKVHNGEIIDKFERFSNPHERLSETIINLTHITDDMLTDAPEIEEVLTEFKEWVGDAIFVAHNASFDMGFIDTGYERLGFGPSTNGVIDTLELSRTINTEYGKHGLNFLAKKYGVELTQHHRAIYDTEATAYIFIKMVQQMKELGVNNHLEINKKLTNEDAYKRARPSHVTLIVQNQEGLKNLFKIVSASLVKYYYRTPRIPRSLLNEYREGILIGTACDEGELFTAVMQKDQSEVEKIAKFYDFIEVQPPALYQDLMDRELIRDNETLTQIYKRLIDAGKSANIPVIATGNAHYLYEHDAIARKILIASQPGNPLNRSTLPEAHFRTTDEMLDDFHFLGEEKAYEIVVTNTNELANKIEKVVPIKDKLFTPRMDGANEEIRELSYSNAKKLYGEDLPQIVIDRLEKELDSIIGNGFSVIYLISQRLVKKSLDDGYLVGSRGSVGSSFVATMTEITEVNPLPPHYICSHCKTSEFFDDGSVGSGFDLPDKKCPTCGNELIKEGQDIPFETFLGFKGDKVPDIDLNFSGEYQPNAHNYTKVLFGEDKVFRAGTIGTVAEKTAFGFVKGYLNDQGIHKRGAEIDRLVKGCTGVKRTTGQHPGGIIVVPDYMDIYDFTPIQFPADDQSAAWMTTHFDFHSIHDNVLKLDILGHDDPTMIRMLQDLSGIDPKTIPVDDKETMQIFSGPESLGVTEDEILCKTGTFGVPEFGTGFVRQMLEDTKPTTFSELVQISGLSHGTDVWLGNAQELIRQGICDLSSVIGCRDDIMVYLMYAGLEPSMAFKTMEFVRKGRGLTDEMVEAMKENNVPDWYLDSCRKIKYMFPKAHAAAYVLMAVRIAYFKVHHPLYYYAAYFTIRASDFDLITMIKDKTSIRNTVKDMYSRYMDLGKKEKDVLTVLEIMNEMAHRGFRLQPISLEKSQAFDFIIEGDTLIPPFISVPGLGENVAQRIVEAREEGPFLSKEDLNKKAGLSQKVIDYLDELGSLPDLPDKAQLSIFDM
What is the function of this protein?
Required for replicative DNA synthesis.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.
What are the official names of this protein?
DNA polymerase III PolC-type, PolIII.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. PolC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HYD2G_PYRFU
Sequence: MNPYRSYDARIIEVKELTSREKLFSLKFLDNEIEENFTFKPGQFVIVDIRGFGEFPISLCSSPTRRPIQLCIRRVGRMTKFIHKMNEGDIIGIRGPYGNGFPMDLMEGSNLILIAGGLGMAPLRSVLWYAIDSGKYEKIYLFYGTKSYEDILFRDEIIHLLKHGEKLNCHVKLAYEVETPSCIYLERGFSEKVCKGVVTDLFRGEEFDVENSYALICGPPVMYKYVIRELLDRGLSPGRIYMTLERRMRCGVGKCGHCIVGTSVSIKYICKDGPVFTYWDALSTRGLI
What is the function of this protein?
Part of a bifunctional enzyme complex that functions as a hydrogen-evolving hydrogenase with sulfur-reducing activity.  May play a role in hydrogen cycling during fermentative growth.  Activity exhibited with NAD in addition to NADPH.  The beta and gamma subunits form the sulfur-reducing component that catalyzes the cytoplasmic production of hydrogen sulfide in the presence of elemental sulfur.
What are the official names of this protein?
Sulfhydrogenase 2 subunit gamma, Hydrogenase-II subunit gamma, H-II gamma, Sulfhydrogenase II subunit gamma, Sulfur reductase subunit ShyC.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_PARUW
Sequence: MVRATNAVASHRRKKRLFKLAKGFVGDRKNHLRLTSGAVMRAMAYNYAHRKQKKRDFRSLWIMRLNAAARINGISYSKFIYGLKKAQCELDRKVLADMAIRDPGSFAAIVGFAKEALA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: NRAM_I73A5
Sequence: MNPNQKIITIGSVSLIIATICFLMQIAILVTTVTLHFKQYECDSPANNQVMPCEPIIIERNITEIVYLTNTTIEKEICPKLVEYRNWSKPQCKITGFAPFSKDNSIRLSAGGDIWVTREPYVSCDPGKCYQFALGQGTTLDNKHSNDTIHDRTPHRTLLMNELGVPFHLGTRQVCIAWSSSSCHDGKAWLHVCVTGYDKNATASFIYDGRLVDSIGSWSQNILRTQESECVCINGTCTVVMTDGSASGRADTKILFIEEGKIVHISPLSGSAQHVEECSCYPRYPGVRCICRDNWKGSNRPVVDINVKDYSIDSSYVCSGLVGDTPRNNDRSSNSYCRNPNNEKGNHGVKGWAFDDGNDVWMGRTISEDSRSGYETFKVIGGWSTPNSKLQINRQVIVDSDNRSGYSGIFSVEGKSCINRCFYVELIRGREQETRVWWTSNSIVVFCGTSGTYGTGSWPDGADINLMPI
What is the function of this protein?
Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates.  Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release.  Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell.  Otherwise, infection would be limited to one round of replication.  Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors.  May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells.  Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport.  May additionally display a raft-association independent effect on budding.  Plays a role in the determination of host range restriction on replication and virulence.  Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
What are the official names of this protein?
Neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 34 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type II membrane protein. Note=Preferentially accumulates at the apical plasma membrane in infected polarized epithelial cells, which is the virus assembly site. Uses lipid rafts for cell surface transport and apical sorting. In the virion, forms a mushroom-shaped spike on the surface of the membrane.
Protein: VP5_BTV1S
Sequence: MGKVIRSLNRFGKKVGNALTSNTAKKIYSTIGKAADEFLESEIGSAAIDGLVQGSVHSIITGESYGESVKQAVLLNVLGSGEEIPDPLSPGERGIQAKLKELEDEQRNELVRLKYNDKIKEKFEKELEEVYNFYNGEANAEIEDEKQFDILNKAVTSYNKILTEEDLQNRRLATRLQKEIGERTHAETVMVKEYRDKIDALKNAIEVERDGMQEEAIQEIAGMTADVLEAASEEVPLIGAGMATAVATGRAIEGAYKLKKVINALSGIDLTHFTHYENRPSVVSTILEYRAKEIPDNALAVSVLIKERAIQENHKELMHIKNEILPRFKKAMDEEKEIMRDRRQMIHPKVMMKFKIPRAQQPQIHVYSAPWDSDDVFFFHCISHHHANDSFFLGFDLSIDLVHYEDLTAHAHAIGAAQTAAGRTLTEAYREFLNLAISKAFGTQMHTRRLVRSKTVHPIYLGSLHYDISFSDLRGNAQRIVYDDELQMHILRGPIHFQRRAILGALKFGCKVLGDRLDVPLFLRNA
What is the function of this protein?
VP5 protein is one of the two proteins (with VP2) which constitute the virus particle outer capsid.  Acts as a membrane permeabilization protein that mediates release of viral particles from endosomal compartments into the cytoplasm.  Permeabilization activity is probably negatively regulated by VP2 and is triggered by endosomal degradation of VP2 and exposure to low pH (By similarity).
What are the official names of this protein?
Outer capsid protein VP5.
What is the protein family that this protein belongs to?
Belongs to the orbivirus VP5 family.
What are the subcellular locations of this protein?
Virion.
Protein: RS16_BORHD
Sequence: MSVRIRLKRMGAKKRPYYRIVVMDSASPRDGRAIEELGYYHPVEMQNQVKINEDKFRDWIGKGAIPSDTVKRILNKNNFKVES
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.