PharMolix/UniProtQA huggingface dataset:
Protein: RL2_ERWT9
Sequence: MAIVKCKPTSPGRRHVVKVVNLELHKGKPFAPLVEKNSKSGGRNNNGRITTRHIGGGHKQAYRIVDFKRNKDGIPATVERLEYDPNRSANIALVLYKDGERRYILAPKGLKAGDQIQSGVDAAIKAGNTLPMRNIPVGSTVHNVEMKPGKGGQIARSAGTYVQIVAREGSYVTLRLRSGEMRKVESDCRATLGEVGNAEHMLRVLGKAGAARWRGVRPTVRGTAMNPVDHPHGGGEGRNFGKHPVSPWGLQTKGKKTRSNKRTDKFIVRRRSK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: KATG_MARN8
Sequence: MSETNSGGKCPVMHGANSTENRDVMNWWPEALNLDILHQHDHKTNPMGEDFDYREEVKKLDFEAVKKDLHALMTDSQDWWPADWGHYGGLMIRMSWHAAGTYRIQDGRGGGGTGNQRFAPLNSWPDNVSLDKARRLLWPIKKKYGNKLSWADLIILAGTVAYESMGLPSYGFSFGREDIWHPEKDIYWGNEKEWLAPSDERYGDVEKPDTMENPLAAVQMGLIYVNPEGVNSQPDPIKTGEQVRVTFARMAMDDEETAALTAGGHTVGKCHGNGDAGALGPEPEAADVEEQGFGWSNPNMKGKAANAVTSGIEGAWTTHPTKFDMGYFDLLFGYEWELKKSPAGAWQWEPINMKEEDKPLDASDPSKRHNPIMTDADMAMKMDPKYRAICEKFMADPEYFKDCFARAWFKLTHRDLGPKARYIGPEAPAEDLIWQDPVPAGSTDYCEEVVKEKVADSGLSISEMVSTAWDSARTFRGSDMRGGANGARIRLAPQKDWEGNEPARLSKVLKVYEQISAETGASVADVIVLAGSVGIEKAAKAAGYEVRVPFLKGRGDATDEMTDAPSFEYLEPVADGFRNWQKKDYIVKPEELLLDRAQLMGLTAPEMTVLIGGMRVLGTNHGGTKYGVFTDREGQLTNDFFVNLTDMAYSWKPVGNGTYEIRDRKTDQTKWTASRVDLVFGSNSILRSYAEVYAQDDNGEKFVKDFIAAWTKVMNNDRFDVQA
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: YOSX_BPSPB
Sequence: MEVGDKIHNTNEQITALEKKKYQIETTLLEKQRDLLKLETQQNKAKLELLFELSEVLTQLEGEEWVSATIALRIIKRNKRKYLDLFDLNDDKAYVNKDKFKFLHDEFFELKQQLNDI
What are the official names of this protein?
Uncharacterized protein yosX.
Protein: POL2_CPSMV
Sequence: MSTFRYKCKQLDQEIQWWFSGTGNRAFWKFEKKLAELHEWYWSLALDPFPYSGFFYKCFYELFQLWVKLGLIVQVSYLILLLDFFVYTIPKKMASQIETTVEKVKQSGIPADILRKRAVDYWKKNNSHNSQMQDVLPNVDEIYEGMRANIAKYLGRSSTVTSIAKLGKCKVYRKKNIPLANLPSLQTSCVPITLTEESVGNSDYTTEETNSEVKSLHVGAIEIVMNSFASSDCNILGGFLLIDTCHTDINNAIRSIFVAPMRGGRPIRMISFPDTLVQIEPNMNKRFQLLCTTSNGDFMQGRDLAMMHVNVLAHAVTHTSTYTPTPYYEKILSREKGFIVEYLNRMTYAVHNQNHPTEKDLLESDFQFDFEGQPVLKRISSTKAIFSKGSSFRYMISGKKEHKIDKPRLEEDGSKSYIDGLQDTFDTTHATLQSGADLFKRNLDDVSTISDTMLGAMIGQTKVVIPKTLVAGTVLKSGPLSDVMQQGSFRSTIALQRTHIITGKIHVVAMLETAVNTGLGLAICFNSGIRGKASADIYATCSQDAMIWNPSCTKVMQYAFNPNPCSDGWSLAFLERTGYHCVVTCVTGWTGTPLQDTFMTINWHISREACVPKIYTIFDPEPDMMLNRWMGRAIFPQQSTQVVRRMPLSIGGGAGAKNSILMNLPNAILSMWRYFKADLEFELIKMSSPYINATIAFFVAFGDLSDDTVNFEAFPHKLIVFSDKQDRTTISFSKDEFLMAWSTQVRPDTKLSEDGCPYLYAITHNGVSSSVEGDFILGIKMVGLKAVENIGVNPGIIGSRLLGAVAQSGQTQQVWNKIWRIGTPPQATDGLFSFSIDLLGVELVTDGQEGAVSVLSSSPVANLLRTAAWKCGTLHVKVVMTGRVTTTRANWASHTQMSLVNSDNAQHYEAQKWSVSTPHAWEKEFSIDICGPNRGFEMWRSSWSNQTTWILEFTVAGASQSAIFEIFYRLDNSWKSAGNVLMPPLLVGNPRLDIKGRAAAAA
What is the function of this protein?
Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs.
What are the official names of this protein?
RNA2 polyprotein, Genome polyprotein M, M RNA polyprotein, Middle component RNA polyprotein, P2.
What are the subcellular locations of this protein?
[Movement protein]: Host cell junction, host plasmodesma. Note=Assembles in tubules that are embedded within modified plasmodesmata. SUBCELLULAR LOCATION: [Large capsid protein]: Virion. SUBCELLULAR LOCATION: [Mature small capsid protein]: Virion.
Protein: RL19_ECO27
Sequence: MSNIIKQLEQEQMKQDVPSFRPGDTVEVKVWVVEGSKKRLQAFEGVVIAIRNRGLHSAFTVRKISNGEGVERVFQTHSPVVDSISVKRRGAVRKAKLYYLRERTGKAARIKERLN
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: OBG_PELTS
Sequence: MFYDRARIFVKGGDGGNGCVAMRREKYVPEGGPWGGDGGRGGNVILRADGGLRTLVDFRYKRHYKAERGRHGEGKNMHGASGEDLVIRVPAGTVVKDAATGELIADLVRDGQEAVVARGGRGGRGNARFVTPQNRAPRMAEKGEPGEERWLDLELKLLADVGLVGFPNAGKSTLISRVSAARPKIASYPFTTITPNLGVVRVDDGRSFVMADIPGLIEGAHKGAGLGHDFLRHVERTRLLVHVLDTAGSEGRDPVQDFLVTNRELSLYNPALGRRPQVIAANKMDLDGAAENLARLKEAYGGKYEIFPVSAVTGQGLEALVYRVSALLEEIPAGAAVPEALERPVIHQAGPRFTVCREEGVFLVGGKEIERHVVMTDLKNEEAVERLQRIIRRMGIEEALKEAGIKDGDTVRIGDYEFEYVE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_BRASB
Sequence: MSRRHSAEKREVLPDPKFGNIIVTKFMNSVMYAGKKSVAESIVYGAFGIIESKTKQNPLTVFEQALDNVMPTIEVRSRRVGGATYQVPVEVRSTRRQALGIRWLISAARDRNEKTMTERLSAELLDASNNRGNAVKKREDVHRMAEANRAFSHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RS15_GRAFK
Sequence: MYLTSEKKEEIFSKHGKGKNDTGSAEGQIALFTHRIAHLSEHLKTNRKDYNTERSLVMLVGKRRSLLDYLMKKDIIRYRAIVKELGLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: PA2B1_CROSS
Sequence: MRALWIVAVLLVGVEGHLLQFNKMIKFETRKNAIPFYAFYGCYCGWGGRGRPKDATDRCCFVHDCCYGKLAKCNTKWDIYPYSLKSGYITCGKGTWCEEQICECDRVAAECLRRSLSTYKYGYMFYPDSRCRGPSETC
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that inhibits neuromuscular transmission by blocking acetylcholine release from the nerve termini.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Basic phospholipase A2 Mtx-b, svPLA2, Mojave toxin basic chain, Phosphatidylcholine 2-acylhydrolase, Phospholipase A2 CB1.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DER_CHLFF
Sequence: MLRIAILGRPNVGKSSLFNRMCKQSLAIVNSQEGTTRDRLYGEIRGWSVPVQVIDTGGVDKDSEDHFQKHIYKQALAGAGEADILLLVIDIRCGITEQDAAIAKQLLPLKKPLILVANKADTLKDEHHVHELYKIGISEILTVSASHDKHIDRLLQKIKTLANIPEIAEEPVEEIEEEAQISSHEILSPEESLSDYEEEEILFSKPPASDKPLKIALIGRPNVGKSSIINGLLNEERCIIDNIPGTTRDNVDILYSHNDRSYLFIDTAGLRKMKSVKNSIEWISSSRTEKAIARADICLLVIDATHCLSSYDKRILSLISKHKKPHIILANKWDLIKGVRMEHYIRDLRSTDVYIGQSRILCISAAKKRNLRHIFSSIDELHETVSRKVPTPVVNKTLASALQKHHPQVINGRRLRIYYAIHKTATPFQFLLFINAKSLLTKHYECYLKNTLKTSFNLYGIPFDLEIKEKAKRTN
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: MMD1_ARATH
Sequence: MPVPIIETCRKRKRKPKVYNLQRFGEDGFPIQRNGAFRDQIRVFLRDCAEIEDYDIRGMTVWCTLLSHETKSSLIPLYIVEENVKHSSEPYCDHCRCTGWSNHFVSKRKYHFIIPIDTEWSLPLEDDAFDSQSHVLHGLIHCNGFGHLVCVNGMESGSKYLCGREIVDFWDRLCNSLGARMITVEDLAKKRSVELRLLYGVAYGHSWFGRWGYKFCCGSFGVTKNEYENAIEALGSLEIDQIEFDFGELRQSKEINQVFRYYREMSEGHLKTFRDLLRFMLIIKSHASPQKLLPVTPPLLTDSPHQKRSSRLLLKKSDVADNDKSPKYRNYSTVAANLGSRWPVRRLIFAAEVIVESLKEMKALKQNGMTRQDVRDSARLHIGDTGLLDYVLKSMNNVVVGDVLVRRYVDPITRILHYTIQDLDDAVKAKEPKKKEAVVLEEITPLRILTPLKPGADVYGDLLLLYTNVLLNYPESELVRSATQAILDSKHFIKEWPIWDNNDTVLQFLCRINPSLVDVRSEQTTELPPGELVTVPLQATVYDLKQAIEETFRDTYCILSNFVVTEIDEVEEDMSLIGSCSALTVRGHGIDLESKLKCQGGCDTWMVKCICRARDDDGERMISCDVCEVWQHTRCCGIDDSDTLPPLFVCSNCCEEFAEQQRKVLQPKYEFPSSENVFLLESADDFFGDQRCLGMIFPEENYLL
What is the function of this protein?
Probable transcription factor required for chromosome organization and progression during male meiosis (e. g.  microsporogenesis) (PubMed:12782723, PubMed:14573517).  Necessary for fertility and meiotic progressive compaction of prophase I chromosomes to metaphase I bivalents (PubMed:27385818).  Together with JMJ16, promotes gene expression in male meiocytes in an H3K9me3-dependent manner, and contributes to meiotic chromosome condensation by triggering some condensin promoters (e. g.  CAP-D3 and CAP-H) (PubMed:32572214, PubMed:27385818).
What are the official names of this protein?
PHD finger protein MALE MEIOCYTE DEATH 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: YNFA_ECOL6
Sequence: MIKTTLLFFATALCEIIGCFLPWLWLKRNASIWLLLPAGISLALFVWLLTLHPAASGRVYAAYGGVYVCTALIWLRVVDGVKLTLYDWTGALIALCGMLIIVAGWGRT
What are the official names of this protein?
UPF0060 membrane protein YnfA.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ARP_EUGGR
Sequence: MSHLWCWLFLVLCLACLVLSIEAKDSDGDGLLDVDEINVYFTDPYNADSDQDGLTDGLEVNRHQTHPQDKDTDDDSIGDGVEVNNLGTNPKDPDSDDDGLTDGAEVNLYRTDPLDADSTTTGCPMGGGAEVRHRPQNGDTDDDGLTDGAEVNVHRTNPQDGDSDDDGLSDGAEVNTYHSNPKDGDSDDDGVSDGAEVNPKLKDSDGDGLTDEEEIKLYRTDPFCADSDFDGLLDGEEVKVHKTNPLDGDSDDDGLGDGAEVTHFNTNPLDADSDNDGLDDGEEINVHGTDPEDPDSDNDGLNDGDEVNVYNTDPEEDDSDEDGVCDGAEVNVHHTNPKDEDSDNDGIPDGAEINTHKTDPNDEDSDDDGIADGAEVTLTDSDGDGLPDEDEVALYNTNPANADSDYDGLTDGAEVKRYQSNPLDKDTDDDGLGDGVEVTVGTDPHDATVTTTGSRTAVEINVHGSDPNDEDTDDDGLTDGAEVNLHRTDPEDADTDDDGLTDGAEVNTYRTNPKLADSDGDGLSDGAEVNTHKSDPNDGDSDDDGVPDAAEAKVKDSDGDGLSDTDEVRFRTNPKLADTDFDGLTDGAEILKHKTDPRNRDTDGDGVADGLEVNTYGSDPKDADTDDDGLTDGAEINVHDTNPTDADSDDDGLSDGAEVMTYHTNAKDGDSDDDGKADGAEVSASTDPWRSDHSV
What is the function of this protein?
May function as a calcium-binding protein.
What are the official names of this protein?
Calcium-binding acidic-repeat protein, ARP.
What are the subcellular locations of this protein?
Secreted. Endoplasmic reticulum.
Protein: PDH_CAMFO
Sequence: MANYITIAIIVGIVCGQALSVEDVDRNLLELNLPYGRGLDSELQLARLMLAAPRFCHPKRNSELINSLLGLPKNMHNAGK
What is the function of this protein?
Neuropeptide PDF is the main transmitter regulating circadian locomotor rhythms.
What are the official names of this protein?
Pigment-dispersing hormone peptides.
What is the protein family that this protein belongs to?
Belongs to the arthropod PDH family.
What are the subcellular locations of this protein?
Secreted.
Protein: ARP19_BOVIN
Sequence: MSAEVPEAASAEEQKEMEDKVTSPEKAEEAKLKARYPHLGQKPGGSDFLRKRLQKGQKYFDSGDYNMAKAKMKNKQLPTATPDKTEVTGDHIPTPQDLPQRKPSLVASKLAG
What is the function of this protein?
Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.  When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase.  May indirectly enhance GAP-43 expression (By similarity).
What are the official names of this protein?
cAMP-regulated phosphoprotein 19, ARPP-19.
What is the protein family that this protein belongs to?
Belongs to the endosulfine family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OADC_PARXL
Sequence: MLNEHGRRLLLGPTTQRRRLRQILDREDCVTMATIFDPVSARLAEQLGYEAGLMGGSLASYAVLGAPDLIVLTLTELAEQVHRCTRVSDVPLVVDGDHGYGNALSVMRTVHELDRAGAAAVTIEDTLLPRPYGSSGKPALVSFDEAVARVEAAVAARGDSDLLVLGRTSAATLNGIEDAVARFKAFEAAGVDAIFLPGPQQREQIDAISDAVKVPLLMAGAPEALCDPAYLATRRVKAWSAGHQTFSVALKALHDSMQLVRSGTLSLHLPGQASKQLLEQATGVPEYDEWTRQYLAGGA
What is the function of this protein?
Catalyzes the decarboxylation of oxaloacetate into pyruvate.  Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate.
What are the official names of this protein?
Oxaloacetate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family.
Protein: GLMM_HYDCU
Sequence: MKKEKKYFGTDGIRDQVGKGLICPDKILKLGWATGKVIKDHGESVVMIGKDTRISGYMFESALEAGFIAAGVDVMLLGPMPTPAVAYLTQTFHADAGIVISASHNPHHDNGIKFFSAKGQKISDAIEHEIEAAYEQDLSIVSSSDLGRAKRIDDAAGRYIEFCKSTYEGAKKLDGFKIVLDCAQGATYHIAPMVFKELGAEVVAIGVEPDGININQNCGATDLAQLQARVVAEKADFGIAFDGDGDRVMMVDAQGDVVDGDEILYILATGTNLPIKGVAGTLMSNLGLENALKEKGIELVRTQVGDRYVMEALREKGWVLGAESSGHVLCLNKTTTGDGIVAALQVVSIMVNSGKTLTELRQGMTKYPQILQNVRVESKVGLNTNAALKKAVQDSEERMGGKGRVLIRASGTEPLIRVMVEGDSRSMIESEVKSLVELVKTEFC
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: RSMG_STAAE
Sequence: MTVEWLAEQLKEHNIQLTETQKQQFQTYYRLLVEWNEKMNLTSITDEHDVYLKHFYDSIAPSFYFDFNQPISICDVGAGAGFPSIPLKIMFPQLKVTIVDSLNKRIQFLNHLASELQLQDVSFIHDRAETFGKGVYRESYDVVTARAVARLSVLSELCLPLVKKGGQFVALKSSKGEEELEEAKFAISVLGGNVTETHTFELPEDAGERQMFIIDKKRQTPKKYPRKPGTPNKTPLLEK
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TNR6_RAT
Sequence: MLWIMAVLPLVLAGPELNVRMQGTDSIFEGLELKRSVRETDNNCSEGLYQVGPFCCQPCQPGERKVKDCTTSGGAPTCHPCTEGEEYTDRKHYSDKCRRCAFCDEGHGLEVETNCTRTQNTKCRCKENFYCNASLCDHCYHCTSCGLEDILEPCTRTSNTKCKKQSSNYKLLWLLILPGLAILFVFIYKRYRKRQPGDPESGIPSPESVPMNVSDVNLNKYIWRTAEKMKICDAKKFARQHKIPESKIDEIEHNSPQDAAEQKIQLLQCWYQSHGKTGACQALIQGLRKANRCDIAEEIQAMVWEDHENSISNSRNENEGQSLE
What is the function of this protein?
Receptor for TNFSF6/FASLG.  The adapter molecule FADD recruits caspase-8 to the activated receptor.  The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.  FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both (By similarity).
What are the official names of this protein?
Tumor necrosis factor receptor superfamily member 6, Apo-1 antigen, Apoptosis-mediating surface antigen FAS, FASLG receptor.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Membrane raft.
Protein: HRCA_STAS1
Sequence: MISDRQLSILNAIVEDYVDLGQPIGSKTLIERHKLNVSPATIRNEMKQLEDLELIEKTHTSSGRYPSESGIRYYVNQLLQETSHQQQTKMQRLKDLVIENHYDLSSTLSDFANELSIASQYTTLVMRPNHKQDIINNIHLIRANAYLVIMVVVFTSGHVEHLHLASEVPLSNDELTKISNFVTAKYNEWNNHRFENELNAFVKSDTEKDFIKDMLNMIDIHFDNQSNGIFMGGKVKLIDALNESNVSSIQPILQYIESNKITQLLDEMSNTSINVKIGHEIESSLSDISIVTSEYHIDDRLKGQIAVIGPTAMNYQNVIRLLNTIW
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: ARGB_CAMJJ
Sequence: MQKYLEKANVLIEALPYIRKFNSKIILIKYGGSAMENEELKHCVMQDIALLKLVGLKPIIVHGGGKDISAMCEKLGVKSEFKNGLRVSDKATTEVASMVLNHINKNLVHSLQNLGVKAIGLCGKDGALLECVKKDENLAFVGTIQKVNSKILEELLEKDFLPIIAPIGMDENFNTYNINADDAACAIAKALRAEKLAFLTDTAGLYEDFNDKNSLISKISLEQAKILAPKIEGGMHVKLKSCIDACENGVKKVHILDGRVKHSLLLEFFTDEGIGTLVG
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_SHEB8
Sequence: MAKQIQAIRGMNDILPTQSPLWQKVEAVLRSSVSAYGYSEIRTPIVENTDLFKRSIGEVTDIVEKEMYTFADNNGDSLTLRPEGTASTVRAGNENGLLYNQEQRLWYMGPMFRHERPQKGRYRQFNQFGVEVYGIGTADIDAEVLMLSARLWEKLGISDHVSLELNTLGDPAERAVYRDALIAFLEQHKDALDEDSKRRMYSNPLRVLDSKDQNVQAILAGAPELMDFLGEESKTHFSQLRELLDAVGIKYTINPRLVRGLDYYNRTVFEWVTSSLGSQGTVLAGGRYDGLVAQLGGKDTPAVGFAMGLERIVLLLETLELNKDIPSEVDVYVTAMGDSCLVEAIKIAQELRSALPNLKVMSHCGGGNVKKQMKRADKSGASVALLIGEDELAEGMVTVKHLRNDIEQQRVARSALGAFLAELAIK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCA_HALMA
Sequence: MSDEFDAVVGKVRARASPTDDERAQLQRVADAVMADAEAAIADLPVEAEVVQVGSTARGTWTAGDRDVDVFVCFPPSIDREALEEYGLAVGHDVLPDGREEYAEHPYVVGEREGYAVDLVPCYAVENATEIQSAVDRTPFHTRYLQERLDDNSAAEVRVAKQFLKGIGVYGSDLRTRGFSGYLTELLVLEFGGFRAFLEAVADWHPPVRLDPDDHGSETFDDPLVVIDPTDPERNVAAVLSETNVATLQHYARDLLAEPRVSLFTEDDPCPFEAADVEAAVSQRGTTPVALRFAAPDVVDDQLWPQLRKSLDGLCSELDRRGFEVLRSAAFVEDDSGKPETLDTESRGRDVVLLLEFAVAEQPAVERHEGPPVHVREHASGFFQKYDDNSEVAGPFIDGDRYVVERQRAFTTATGFLSSAAVYDVGLGQRIESALENGYEVLVGTDIAALADGFGVDLASYFDPKP
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
Protein: HIS6_JANSC
Sequence: MLKTRIIPCLDVAEGRTVKGVNFVDLIDAGDPVEQARAYDLAGADELCFLDIKATHENRGTMYDLATRTAEQCFMPLTIGGGVRTVDDVRNLLLAGADKVSFNSAAVADPDCVARAADKFGSQCIVVAIDAKTVRPPAPLRGDPGRWEIFTHGGRKPTGIDAVEFAKTVVAKGAGEILLTSMDRDGTKAGFNLPLTRAVSDAVPVPVIASGGVGTLDHLVEGVTQGGASAVLAASIFHFGTYTIGEAKAHMAKAGIPVRLT
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_ECOSE
Sequence: MAGAKEIRSKIASVQNTQKITKAMEMVAASKMRKSQDRMAASRPYAETMRKVIGHLAHGNLEYKHPYLEDRDVKRVGYLVVSTDRGLCGGLNINLFKKLLAEMKTWTDKGVQCDLAMIGSKGVSFFNSVGGNVVAQVTGMGDNPSLSELIGPVKVMLQAYDEGRLDKLYIVSNKFINTMSQVPTISQLLPLPASDDDDLKHKSWDYLYEPDPKALLDTLLRRYVESQVYQGVVENLASEQAARMVAMKAATDNGGSLIKELQLVYNKARQASITQELTEIVSGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ATPA_CAMJE
Sequence: MKFKADEISSIIKERIENFDLNLEIEETGKIISVADGVAKVYGLKNIMAGEMVEFENGDKGMALNLEESSVGIVILGKGEGLKEGASVKRLKKLLKVPVGEALIGRVVNALGEPIDAKGVINANEYRFVEEKAKGIMARKSVHEPLHTGIKAIDALVPIGRGQRELIIGDRQTGKTTVAVDTIISQRGQGVICIYVAIGQKQSTVAQVVKRLEEHGAMEYTIVVNAGASDPAALQYLAPYTGVTMGEFFRDNAKHALIVYDDLSKHAVAYREMSLILRRPPGREAYPGDVFYLHSRLLERASKLNDELGAGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLETDLFNSGIRPAINVGLSVSRVGGAAQIKATKQVSGTLRLDLAQYRELQAFAQFASDLDEASRKQLERGQRMVELLKQPPYSPLSVEKQVVLIFAGTKGFLDDIAVSRIKEFEDGIYPFIEAKHPDIFEQIRSKKALDSDLEEKLAKAINEFKANHL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TMCO1_DANRE
Sequence: MSTMFADTILIVFISICTALLAEGITWVLVYRTDKYKRLKAEVEKQSKKLEKKKETITESAGRQQKKKIERQEEKLKNNNRDLSMVRMKSMFAIGFCFTALMGMFNSIFDGRVVAKLPFVPLSYIQGLSHRNLLGEDYTDCSFIFLYILCTMSIRQNIQKMLGLAPSRAATKQAGGFLGPPPQAAKFS
What is the function of this protein?
Calcium-selective channel required to prevent calcium stores from overfilling, thereby playing a key role in calcium homeostasis (PubMed:27212239).  In response to endoplasmic reticulum (ER) overloading, assembles into a homotetramer, forming a functional calcium-selective channel, regulating the calcium content in endoplasmic reticulum store (By similarity).  Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes (By similarity).
What are the official names of this protein?
Calcium load-activated calcium channel, CLAC channel, GEL complex subunit TMCO1, Transmembrane and coiled-coil domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the TMCO1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Note=The first transmembrane region is required for localization to the endoplasmic reticulum.