PharMolix/UniProtQA huggingface dataset:
Protein: NSE4A_ARATH
Sequence: MRKTVKRESEATGGKREADDEPEKLRSVKKEKQRKTEADSVRPDEPPPPQEEEQGISDRRILRSKYLSLQNEINDCKDDLMKIDSDKFSRIINAVENLHQQVRKPREQIADAEALLDIANTLMSSVKSQSAHGVSPAEFVNALISGFGQGSLGIDTDETAQVSLKWKDLGFAVCSTVLVSCGCSTMLGPMDTELKQRKRAPNRKRTKPGEGVRPDEVDDSQSEEKTDTDKNMTIMFNILGKKKRVQLENLVLNRRSFAQTVENLFALSFLAKDGRVEIIVDKSGSHFAMPRNAPDANVVMSGEVIYNHFVFRLDFKDWKLMSEMVPLGEELMPHRQTAVASSSCPAASAPASADFTQDTQTTPIRKLSRNRGLVVQEETVVEDTPDKEGDGTRRRCKRRLTSS
What is the function of this protein?
Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
What are the official names of this protein?
Non-structural maintenance of chromosomes element 4 homolog A, Non-SMC element 4 homolog A.
What is the protein family that this protein belongs to?
Belongs to the NSE4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KAD_STRAW
Sequence: MRIVLVGPPGAGKGTQAAFLAKNLGIPHISTGDLFRANISQQTELGKLAKSYMDEGNLVPDEVTIAMAKDRMEQPDAVNGFLLDGFPRNVKQAEALDEMLKSEGMKLDAVLDLEVPEDEVVKRIAGRRICRNDSAHVFHVSYKPPKQEGVCDVCGGELYQRDDDSEETVRRRLEVYHTQTEPIIDYYRAQGLVVTISALGPVEEVTQRAMDALKREDASK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ORF23_TTVV4
Sequence: MSWRPPAHNAEGQEGLWYRSVCQSHGAFCGCGDFVGHLNRLAERLGRPQPPRPPGGPPGPAIRVLPALPPAEGSPRRHNRTENQPCGGGDADFGDQRDAGDGGAAADDLSPADVEDLLDWLDAPDRLSKTPVNNPPLTSPVPVESLVQYKLSTRSTSTRASRSTDGTSDVASLGRQLLKECKQNQQMLSFLQQVQNAQEQRSPWPLQETPYLPGRENAKPGKTRPRKKPRAKQKPKKRRRYRSSSNSSSKSNDSSDAESSTCSSN
What are the official names of this protein?
Probable protein VP2, ORF2/3 protein.
Protein: UL20_SUHVN
Sequence: MEDAAADVDAAADAKLTGENDALLSSAFVGARPPRPRFSSHVVSLLALALALRPACCLVLALHGSRATLAALLTALAFYARAAVCAVLVARNVARDRMPLSPAQQAALGLLAAARLAFLYVALDAGRHYAPALAGALYGADCVCDALAFLLPRAYARSIMH
What is the function of this protein?
Plays an essential role in egress of virus particles from the nucleus, cytoplasmic envelopment and virus-induced cell fusion.  Forms a functional protein complex with gK and this interaction is absolutely essential for their coordinate intracellular transport, gK glycosylation, expression on host cell surface, and function.  Together, they modulate gB-mediated virus-induced cell fusion and virion egress and therefore actively participate in these processes (By similarity).
What are the official names of this protein?
Protein UL20.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae UL20 family.
What are the subcellular locations of this protein?
Virion. Host cell membrane; Multi-pass membrane protein. Host endosome membrane; Multi-pass membrane protein. Host Golgi apparatus membrane; Multi-pass membrane protein. Host nucleus membrane; Multi-pass membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported with gK to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN) (By similarity).
Protein: G6PI_CORJK
Sequence: MPQQRETAHKTREWKKLTEYADATRGTQLRELFTEQPGRSSDMTYNVGPLHVDLSKNLIDERGLRLLLDLARARGLEDYRSAMFDGEHINTTEDRAVLHTALRIPVDREFSIPVGADETQDVAADVHAVLGRMRDFAKALRSGSWQGVTGHTIKHVVNIGIGGSDLGPAMAAQALRPYMTAGITPHFISNIDPADVAGTLDGLDAESTLFVIASKTFTTSETLANAHAARRWLLRNLADAGVDVEGDDAIRDITAKHFVAVSTAAEKVQEFGIDTKNMFEFWDWVGGRYSVDSAIGLSLMAAIGPQDFMRFLEGFHEVDDHFRTEPLEMNIPVLMGMLGVWYTDFLGAQSHAVLPYSEDMARFPAYLQQLTMESNGKSVQLDGTPVEVPSGEIYWGEPGTNGQHAFFQLLHQGTHLVPADFIGFVNPHDDAVAADGTTSMHDMLMSNFFAQTRVLAFGKNAEELKEEGVAPELIPHKVMPGNRPTTTILANKLTPKTLGALIALYEHIVFVQGVIWGINSFDQWGVELGKKQANALLPAVTGAERSDAGDSSTDDLIAYYRQHRD
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZRG8_VANPO
Sequence: MRSFIKSHKNSNSLDGSQSRWNNSEVPNVQRSSADSFNYSGSTVISSNSNTVTSMSIPNNLPNSKNYSPKHTPSFESFHRLANKIPSKLFKKSSNNALNATYNNSLHLGESLSSPPTPRTINTSTDAIQKVRSTESEIEIPSIKGTITHSWGTRSDTGGHSIIVLNEPRSSLSGASNSDYSDLEPAARISGLKRPSIVSIKTNNSFEEYNSTPIITEEEDLKNFDSKIINPSTPNDINAVKYNNRKTQIIGNENLFRTSNLQNKVRKHFISPLENLNENVLEADNKQGVVENVQRKKKVPNLNASPQDTIDGNRSRTISFAETSKTLPQMEGASDADGESDSCSETTDDDDDDNTSKFSFEYNRPNGRTASMKYYSKPEPVNNIYIDDLYEDENFDENMNYDEDSLDGFEFPSNKFDYGNENSDENDDIQGHENYVVQDNNSSKGPKLKSEAPKKVQTYNDLFDLSDDFDYDPSDEYQNETRLIHEMCEDGEASQIDNMMVDENIISPQKSLTSSKSFNNSNVSKSSPLIKPLETPKKKIIVKPVASFADIFNLDDEEDRDFKDDDSCNDESDGEYVLKDPFNIPGGKNLLNRHKSLKKNSSFSLKKIPSNGDSIDNNLMDKKLDKYIVDINKSIKKHSDIPDLHFVPPDNSSDIILPKRSQSLKYHDLSSILDSDVPGSTRDLFFIDEAEEDSYNVKHGLTEEEYLDEINNVPEDFYFSDSEQDMSPMKSPFRRSNTGSFRRTHSFSGKPIGAAKDNTPVKSKLEIKNKTVTFFNHPWTPNSQSGFSGKSPKKSIKKTDNLENSEEEHLLATPKRDDSSAYGFSTPDRQFRKPTPEYLQDYSLSPIQEGYSSVDNSPR
What is the function of this protein?
Involved in maintenance of polarized growth and daughter-cell-specific transcription.
What are the official names of this protein?
Zinc-regulated protein 8.
What is the protein family that this protein belongs to?
Belongs to the ZRG8 family.
What are the subcellular locations of this protein?
Cytoplasm. Bud. Bud neck. Bud tip.
Protein: NTPPB_PSEAE
Sequence: MPDLILASSSPYRRELLTRLRLPFESASPDIDESHRAGESAEELVRRLSASKAEALAGRYPQHLVIGSDQVAVLDGNILGKPHTPERAIQQLRDASGKSVTFLTGLALLNSASRRIQVACVPFTVHFRHLDESRIRRYVEAERPLDCAGSFKAEGLGVSLFRSTEGEDATSLVGLPLIRLVDMLLEEGVEIP
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP).  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
7-methyl-GTP pyrophosphatase, m(7)GTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YceF subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLKA_THESM
Sequence: MKESLKERIKLWKNLYMNAFENAVNAIPNVEGVLLAYNTNIDVIKYLNKDDLERRINQIGKERVFEVIKAPTERISSLEHLFGGILRSIKLGKAIEWFVENEEIRRYLREWGWDELRIGGQAGIMANLIGGVYRIPTIVHVPQNPKLQADLFVDGPIYVPIFEGKELKLVHPKEAVKEENELIHYIYEFPRGFQVFDIQAPRENRFIANADDYNARVYMRKEFKESFEKIAKGVELAIISGLQVLKEYYSDGTTYRDVLDRVESHLNILNRYGVRSHFEFAYTPNRLVREELIGILSKFTSVGLNEVELASIVEIIGDETLAKEVLEGHVFPIIDAINLLMDETGIDRIHLHTYGYYLALTKYRSEEVRDALLFASLAAAAKAMKGNIEKIDHVKDALSVPTNERAIVFEEELEKEFTEFENGLIDMVDRQLAFVPTKIVTSPKSTVGIGDTISSSAFVSEFAMRKS
What is the function of this protein?
Catalyzes the ADP-dependent phosphorylation of D-glucose to D-glucose 6-phosphate and glucosamine to glucosamine 6-phosphate.
What are the official names of this protein?
ADP-dependent glucose/glucosamine kinase, ADP-dependent glucokinase, ADP-GK, ADPGK, Glucosamine kinase, GlcN kinase.
What is the protein family that this protein belongs to?
Belongs to the ADP-dependent glucokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_MYCMM
Sequence: MIDEALFDAEEKMEKAVSVAREDMATIRTGRANPGMFSRIVIDYYGTHTPITQLASINVPEARMVVIKPYEANQLHAIETAIRNSDLGVNPTNDGTIIRVAVPQLTEERRRDLVKQAKHKGEEARVSVRNIRRKAMEELHRIRKDGEAGEDEVARAEKDLDKSTHQYVAQIDELVKHKEGELLEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_ANASK
Sequence: MSADFRHEPVLANEILELLRPRPGELFLDGTLGGGGHSGLLLEAGARVIALDKDPRALAAATARLARFGEAFRAVRSDFRDAKNVLQALGIAAVDGALVDLGVSSPQLDEAERGFSFSRPGPLDMRMGDTGETLEDLLRRIDERELARILREYGEEPFARPVARAVKAALETEAPLDTARLAEVVAGAIPRKAWPHRIHPATRTFQALRIAVNDELGALAAWLDGLPGVLAPGGRAAAISFHSLEDRMVKEKFRALTQACTCPPDLPVCACGAKASFAAITRKAVKASDEEIARNPRARSARLRAVEKLR
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FDB34_GIBM7
Sequence: MFDNYSRESYIFNAGSLGHIKGLTITSHGSPAVHYFGGLPYALPPVGQWRFRVPRRLPKDYRYGTATEPGKFTDGTKICPQPPSSNTPDPSVVSEDCLQLNIWVPAGPPPIHGWPVCFYIHGGFLQVGTSNTKPEDLVSLLNESAFRAIMVLPSYRLNVFGFLASKALAAEASSNGEATGNYGLWDQRLALEWTHENIRLFGGDRSNITVAGYSAGAYSTFQQLAHELFRVPEEKAIIRRVAMFSNSTGVMPKSLQDQQLQCDELLRRLGINLDLSYDEKLASLRAVPHDRLVQAQIGMRISEFRVLADDAFYPLDLMDKINNGEFAKRMKIRGIRLMNGECESEHIMYCRWRTPQESYSAVYQRLLADFSPEVTQKIMEHYCGSSENLPVGYKNWEEFFGRVYANIQVHYLQRGFHNALFTGGLEAGRDVFRYRFERRLDCVAEKIPSEWGVTHLTDIPVWLWGCGYTNGLDDQEKKWLKGWNEGFAVFVNGDEVNWGTKNPKDMRRWRRDGKTDVCEDNSWEDGLKFWKLVNSGHRGTEGKAND
What is the function of this protein?
Carboxylic ester hydrolase; part of the Fusarium detoxification of benzoxazolinone cluster 2 (FDB2) involved in the degradation of benzoxazolinones produced by the host plant (PubMed:19302487, PubMed:26808652).  Maize, wheat, and rye produce the 2 benzoxazinone phytoanticipins 2,4-dihy-droxy-7-methoxy-1,4-benzoxazin-3-one (DIMBOA) and 2,4-dihydroxy-1,4-benzoxazin-3-one (DIBOA) that, due to their inherent instability once released, spontaneously degrade to the more stable corresponding benzoxazolinones, 6-methoxy-2-benzoxazolinone (MBOA) and 2-benzoxazolinone (BOA), respectively (PubMed:11876429).  The first step in the detoxification of benzoxazolinones involves the hydrolysis of the cyclic ester bond of benzoxazolinones by the FDB1 cluster gamma-lactamase MBL1 to aminophenols (PubMed:26808652, PubMed:12788712).  MBL1 is able to convert BOA into 2-aminophenol (2-AP), as well as MBOA into 5-methoxy-2-aminophenol (2-AMP) (PubMed:26808652, PubMed:12788712).  The FDB2 cluster N-malonyltransferase FDB2/NAT1 then metabolizes aminophenols via N-malonylation to non-toxic malonamic acids (PubMed:19302487, PubMed:12788712).  FDB2/NAT1 converts 2-AP into N-(2-hydroxyphenyl) malonamic acid (HPMA) and 2-AMP into N-(2-hydroxy-4-methoxyphenyl) malonamic acid (HMPMA) (PubMed:19302487, PubMed:12788712).  The duplicated dienlactone hydrolases DLH1 and DLH2 may provide redundant function for hydrolyzing the lactone moiety in the BOA molecule (Probable).  The roles of the amidases an other enzymes encoded by the 2 FDB clusters have not been identified so far (Probable).
What are the official names of this protein?
Carboxylic ester hydrolase FVEG_12634, Fusarium detoxification of benzoxazolinone cluster 2 protein FVEG_12634, FDB2 cluster protein FVEG_12634.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
Protein: HIGB1_MYCTO
Sequence: MPPPDPAAMGTWKFFRASVDGRPVFKKEFDKLPDQARAALIVLMQRYLVGDLAAGSIKPIRGDILELRWHEANNHFRVLFFRWGQHPVALTAFYKNQQKTPKTKIETALDRQKIWKRAFGDTPPI
What is the function of this protein?
Toxic component of an atypical, type II toxin-antitoxin chaperone (TAC) system.  Probably an endoribonuclease, neutralized by its cognate antitoxin HigA which also requires SecB-like chaperone MT2006 (AC Q7D7P7).
What are the official names of this protein?
Probable endoribonuclease HigB1, Toxin HigB.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial HigB family.
Protein: TRPG_DROME
Sequence: MMEEENTIRPHQEIRQLTLEEKKFLLAVERGDMAGTRRMLQKAQDTEYINVNCVDPLGRTALLMAIDNENLEMVELLINYNVDTKDALLHSISEEFVEAVEVLLDHENVTFHSEGNHSWESASEDTSTFTPDITPLILAAHRDNYEIIKILLDRGAVLPMPHDVRCGCDECVQSRQEDSLRHSRSRINAYRALASPSLIALSSKDPILTAFELSWELRRLSFLEHEFKNEYQELRKQCQDFATALLDHTRTSHELEILLNHDPTGPVYEHGERMHLNRLKLAIKLRQKKFVAHSNVQQLLASIWYEGLPGFRRKNMALQAVDIIRIGIMFPIFSLAYILAPYSSIGQTMRKPFIKFICHSASYFTFLFLLMLASQRIETFIGGWFFADSSGMLNTMEELPTKRGAKPTFIEWLILAWVSGLIWSEVKQLWDVGLQEYLNDMWNVIDFVTNSLYVATVALRVVSFFQVQKEMIYNSHATDLPRERWDAWDPMLISEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVMDIMKFFFLYVLVLFAFGSGLNQLLWYYADLEKKRCPEVSPMSALLNMNGTNDPNACIVWRRFSNLFETTQTLFWAVFGLIDLDSFELDGIKIFTRFWGMLMFGTYSVINIVVLLNLLIAMMNHSYQLISERADVEWKFARSKLWISYFEEGGTCPPPFNIIPTPKSIWYAIKWMRRVFCSGSSAARREHLKTIRRKAQQASDRDFKYQQIMRNLVRRYVTVEQRKAESQGVTEDDVNEIKQDISAFRCELVEILKNSGMDTNVTAGQGGGGGGKKNRQKERRLMKGFNIAPPGSTGSLAPVAEFSTSLDNYDNQHEILSSTLSTLFTPNFMHKRQQSQAGSGGGGSESPTTPTAPQGTQGAAMTASSQVTKYNKSALKPYNKRIAGHKKRWGTLIEAAKVGNVSKMLGRSKSEDSVCNSSHTSTPVHGQMRVTYAQNSPQQEYGYHGETSSTTISTPTPTISVVSNSPAAHAGVGSHFFHTTSGLTAIAALKRKRKKFSSSKNICPVTESVAAANAAEILNDKTLKRVSSYPAAEAGVQHNPAQLVKPRRHEQTQSQHDSVETNSTFTLSIDPSNTSVNSREPLISTSCVSTTGAIG
What is the function of this protein?
A light-sensitive calcium channel that is required for inositide-mediated Ca(2+) entry in the retina during phospholipase C (PLC)-mediated phototransduction (By similarity).  Forms a regulated cation channel when heteromultimerized with trpl.
What are the official names of this protein?
Transient receptor potential-gamma protein, TRPgamma, Transient receptor potential cation channel gamma.
What is the protein family that this protein belongs to?
Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TMEDA_CANGA
Sequence: MKFLLLLLLAPFISALRFDLKAESKPEQMCIRDFVSEGELVVINIDTDGSLNDGNVLNLYVHDSNGNEYRRLKNFVGEQRIAFTAPATTSFDVCFENTLDSNRGNRNAKRAIELDIESGSQARDWNKISATEKLRPIELELRKIEELTDEIVDELNYLKNREERLRNTNESTNERVRNFSVLVIIVLTSLGAWQVNYLKNYFKSKHII
What is the function of this protein?
Constituent of COPII-coated endoplasmic reticulum-derived transport vesicles.  Required for efficient transport of a subset of secretory proteins to the Golgi.  Facilitates retrograde transport from the Golgi to the endoplasmic reticulum (By similarity).
What are the official names of this protein?
Endoplasmic reticulum vesicle protein 25.
What is the protein family that this protein belongs to?
Belongs to the EMP24/GP25L family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Note=Recycles between endoplasmic reticulum and Golgi.
Protein: SRP72_CANLF
Sequence: MASGGSGGVSVPALWSEVNRYGQNGDFTRALKTVNKILQINKDDVTALHCKVVCLIQNGSFKEALNVINTHTKVLANNSLSFEKAYCEYRLNRIENALKTIESANQQTDKLKELYGQVLYRLERYDECLAVYRDLVRNSQDDYDEERKTNLSAVVAAQSNWEKVVPENLGLQEGTHELCYNAACALIGQGQLSQAMKILQKAEDLCRRSLSEDSDGTEEDPQAELAIIHGQMAYILQLQGRTEEALQLYNQIIKLKPTDVGLLAVIANNIITINKDQNVFDSKKKVKLTNAEGVEFKLSKKQLQAIEFNKALLAMYTNQAEQCRKISASLQSQSPEHLLPVLIQAAQLCREKQHTKAIELLQEFSDQHPENAAEIKLTMAQLKISQGNISKACLILRSIEELKHKPGMVSALVTMYSHEEDIDSAIEVFTQAIQWYQNHQPKSSAHLSLIREAANFKLKYGRKKEAISDLEQLWKQNPKDIHTLAQLISAYSLVDPEKAKALSKHLPSSDSMSLKVDVEALENSPGATYIRKKGGKVAGDSQPKEQGQGDLKKKKKKKKGKLPKNYDPKVTPDPERWLPMRERSYYRGRKKGKKKDQIGKGTQGATAGASSELDASKTVSSPPTSPRPGSAATASASTSNIIPPRHQKPAGAPATKKKQQQKKKKGGKGGW
What is the function of this protein?
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (PubMed:6413076).  The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER (PubMed:6413076).  The SRP complex targets the ribosome-nascent chain complex to the SRP receptor (SR), which is anchored in the ER, where SR compaction and GTPase rearrangement drive cotranslational protein translocation into the ER (By similarity).  Binds the signal recognition particle RNA (7SL RNA) in presence of SRP68 (PubMed:8388879, PubMed:6413076).  Can bind 7SL RNA with low affinity (By similarity).  The SRP complex possibly participates in the elongation arrest function (By similarity).
What are the official names of this protein?
Signal recognition particle subunit SRP72, SRP72, Signal recognition particle 72 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the SRP72 family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum.
Protein: THIG_NAUPA
Sequence: MSDILKIGKYEFTSRLIVGSGKYPDFQTTRDATLASGAEMITVAVRRVNIMDPNEENLMDYFKDTDVKILPNSAGCTTAEEAITLFRLVREATGIDIIKLEVIGDTAKTLYPDVMETLKACEVLAKEDFTIMAYTNDDPIMAKRLENAGAHAVMPLAAPIGSGLGVQNRYNVVFVKDAVNVPVIVDAGIGTASDAAVAMELGADGVLTNTAIAQAKNPIAMAEAMKHAVIAGRMAYKAGRIPKKPYATASSPLEGLIEF
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COMT1_MEDSA
Sequence: MGSTGETQITPTHISDEEANLFAMQLASASVLPMILKSALELDLLEIIAKAGPGAQISPIEIASQLPTTNPDAPVMLDRMLRLLACYIILTCSVRTQQDGKVQRLYGLATVAKYLVKNEDGVSISALNLMNQDKVLMESWYHLKDAVLDGGIPFNKAYGMTAFEYHGTDPRFNKVFNKGMSDHSTITMKKILETYTGFEGLKSLVDVGGGTGAVINTIVSKYPTIKGINFDLPHVIEDAPSYPGVEHVGGDMFVSIPKADAVFMKWICHDWSDEHCLKFLKNCYEALPDNGKVIVAECILPVAPDSSLATKGVVHIDVIMLAHNPGGKERTQKEFEDLAKGAGFQGFKVHCNAFNTYIMEFLKKV
What is the function of this protein?
Catalyzes the conversion of caffeic acid to ferulic acid and of 5-hydroxyferulic acid to sinapic acid (Probable) (PubMed:1898010).  The resulting products may subsequently be converted to the corresponding alcohols that are incorporated into lignins (Probable) (PubMed:1898010).
What are the official names of this protein?
Caffeic acid 3-O-methyltransferase, CAOMT, COMT, S-adenosysl-L-methionine:caffeic acid 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. COMT subfamily.
Protein: ARCC_THEVO
Sequence: MVRIVIALGGNALLRNGEPRNYEVQYSHAIETFKIIRDITEKNETVITHGNGPQVGDIQQSHEISGIMANLHQSVAMSQGYIGEILANAYDEVRSKYSLSKSIFTIITRSVVNRNDPAFASPEKPIGRYYSDQEVDEAKRNGWVMKKFKDGWRRVVPSPEPIEILEEKAIEELVREGHIPLAVGGGGIPVVKENGRIVGIDAVIDKDIASSLLAAQLKADYFMILTDVESVYVNFGKPDQKPLGRIHLNEIEKYYAEGQFADGSMKPKVRAAINFVKNGGKAAFITNLENGSAALSGKAGTVIVP
What are the official names of this protein?
Carbamate kinase.
What is the protein family that this protein belongs to?
Belongs to the carbamate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_THESQ
Sequence: MAYRRRKKKVKKCRLCEMKLDYVDYKDTRLLSEFLTDKGKIIPKRLTGTCAKHQRMVKVAIKRARQMGLLPYLKI
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: AROD_LISW6
Sequence: MNKVVVKNVTFGEGAPKICVPMVGKTVAALKEEAEMLKTIDLDVVEWRVDFYEDVKDLAKVETALDEIRVVLPETPILFTFRSAKEGGELAVSDEFYFELNETLARTGKIDLVDVELFNEEADVLRLIETAHKHDVKVVMSNHDFDKTPAKEEIVSRLTRMEALGADLPKIAVMPKSATDVLTLLDATNTVSEKADQPIITMSMAGTGVISRLAGEVFGSAMTFGAAKKASAPGQIDVNELRHVLDLLHKQF
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: YBEY_ROSS1
Sequence: MSDSERTVDIQVVPPYAAYVDSALIEQAVECTLQMEQVAGPVEVGILITDDAGLQRLNQAYRGVDAPTDVLSFAEADDDSAFVRPPDAPRYLGDIAISWERVVAQAAEYGHSRERELAFLVVHGMLHLLGYDHERSPADEADMRAREEEILRALGLSREE
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WUHO_DROER
Sequence: MCTTISFAEPEIVLGHGRRVLFVNPDDLQIFKEIELPPDLGLKCHETQSQESCPATATSTTAGKEPGGKEQQLAKQPEEGGTSASGSVATSTSVQNVAYSPDGQLLAVTTSGGQKALLLYRSRPENARLLSARPLARAASAVRFCSDSSSVLVTDKTGDCYQYDCVEVEAPPRLLLGHLSVVYDILWSEDQQHIITCDRDDKIRVTNYPATFDIHSYCLGHREFVSGLALLTEQHIASASGDKTLRVWNYIQGKELLQHELPAPAVRLLVRQLEPEKVFQAAVLFYEHVDALGLYRLERSSDDTWSVTATQLVCAEAGSWSISNFTLTSDRIYITGAENERLSLRVYDIATGQPTTNGVPEGWLKMVLDGLGANEEGAPPFIPEDLSVWFKKRFDNVTDYLERKKRRIEEQKQQKC
What is the function of this protein?
Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.  In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.  Required during gametogenesis.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit wuho.
What is the protein family that this protein belongs to?
Belongs to the WD repeat TRM82 family.
What are the subcellular locations of this protein?
Nucleus. Note=Localized to the nuclei of nurse cells, follicle cells and oocytes at early stages, from germarium to stage 4 egg chambers. Also present in the nuclei of spermatocytes and in the apical cells of the testes.
Protein: SYCY2_HUMAN
Sequence: MGLLLLVLILTPSLAAYRHPDFPLLEKAQQLLQSTGSPYSTNCWLCTSSSTETPGTAYPASPREWTSIEAELHISYRWDPNLKGLMRPANSLLSTVKQDFPDIRQKPPIFGPIFTNINLMGIAPICVMAKRKNGTNVGTLPSTVCNVTFTVDSNQQTYQTYTHNQFRHQPRFPKPPNITFPQGTLLDKSSRFCQGRPSSCSTRNFWFRPADYNQCLQISNLSSTAEWVLLDQTRNSLFWENKTKGANQSQTPCVQVLAGMTIATSYLGISAVSEFFGTSLTPLFHFHISTCLKTQGAFYICGQSIHQCLPSNWTGTCTIGYVTPDIFIAPGNLSLPIPIYGNSPLPRVRRAIHFIPLLAGLGILAGTGTGIAGITKASLTYSQLSKEIANNIDTMAKALTTMQEQIDSLAAVVLQNRRGLDMLTAAQGGICLALDEKCCFWVNQSGKVQDNIRQLLNQASSLRERATQGWLNWEGTWKWFSWVLPLTGPLVSLLLLLLFGPCLLNLITQFVSSRLQAIKLQTNLSAGRHPRNIQESPF
What is the function of this protein?
Endogenous envelope proteins may have kept, lost or modified their original function during evolution but this one can still make pseudotypes with MLV, HIV-1 or SIV-1 virions and confer infectivity.  Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection.  The surface protein mediates receptor recognition, while the transmembrane protein anchors the envelope heterodimer to the viral membrane through one transmembrane domain.  The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane (PubMed:14694139).
What are the official names of this protein?
Syncytin-2, Endogenous retrovirus group FRD member 1, Envelope polyprotein, HERV-FRD, HERV-FRD_6p24.1 provirus ancestral Env polyprotein.
What is the protein family that this protein belongs to?
Belongs to the gamma type-C retroviral envelope protein family. HERV class-I FRD env subfamily.
What are the subcellular locations of this protein?
Virion. SUBCELLULAR LOCATION: [Surface protein]: Cell membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the membrane, but localizes to the extracellular surface through its binding to TM. SUBCELLULAR LOCATION: [Transmembrane protein]: Cell membrane; Single-pass membrane protein.