PharMolix/UniProtQA huggingface dataset:
Protein: CYAA_PODAS
Sequence: MPRNDASSRFSSMTGSSTDSARSNITVKPLPSLPPSASSSSPFAASSNQTSNASRSASHGSRRAAPSRLKTDENGQLSRSFKDSDAQVSPTSTSPCVSPSSITSSNSIREHRMSDLADYRRDLAILDPAGGRASRTQQNNPSSGSLSQIAPWMAAAPTPASSGPLPTSFFNDSTDNLSLSSQTSPGLRNATARPSQTTTGSTESPETLYFTDERRPSIASITTTASSQGSRASGARGGIRKLQGFFGEEFPGRDSSEISLSHPIVGKEHRSHSYSHARPHRDRNYSNATDHGRDASPASRPRTPVPKPEVVPFLYQEADDIARYGEAPVRDILSGPDRERFVNDSSQQNNPPKTSGSGRSGHSIGVHLTGHHHRHNKSNEDPRSLRPTVSREDSTISVPKDRNGSSTMYGTRSRAQSPAPSTTGSYWGHKSGSTDGQTSPGQPKKSFLGRLGRRLKEKDDAPDLKKLGPASQSSLHSRPSRQELSKADGQFARGADGKYQPDVRDGIRPDLARPANGPQTFNKFSLSKKAPRSKTQDDLDEAIGPTDRQDVGTVFHLDTNLNNMDGILSKPAPLTPMNAHEIFDEVGSGKGSISYPSSNGAWNAPDSWAVLRDDDAGAQLPDTEDIGSPPRPEEKQHNYCIRVFRADGTFATLQMPLLTSVSELINQIVKKSYLQDPDKFKLVLKKHDLYKVLQSTDRPLLLQKRLLEQVGFEERDRIEDIGREDNSYLCRFLFYPFTDNSYEVMDQMEFLRSQKNNHIDLSGRSLSAIPVQLYPRANEIISLNLSRNLSLQVPRDFISVCPNLRDIKFNNNEARALPKSFGYASRLTMLDASNNRLESLESAALHNLTGLLKLNLANNKLKQLPREFEAFAVLRTLNISSNLLNNFPPFLAKLENLVDLDLSFNTIQSLPDNVGQMTSLERLVITNNELSGSLPPSFKNLRSLRELDIKYNAISNIDVISQLPKLEILSATRNNISQFSGTFERVRSIKLNWNPITKFEIKAPVPTLKALNLSNAQLASIDESFHNMSNLERLELDKNYFVSLPAHIGNLRRLEYFSIAHNSVGELPPEIGCLTELKRLDVRGNNIRKLPMELWWANKLDYLNASSNVLENFPKPASRAPHPPGETNGNTSFPTGRIGPPTGALSQTPSAEELNDPSRRPSQASSSLLSVGPSPVPGGADRKSSMVSVYGKGGRKTSVISRSTTQSSTALATPTASSRKDSSHTQRLTNTFAGSLRYLYMADNQLDDDCFDQLCMLENLRVLNLSYNDLSDMPQRSIKSWPQLVELYLSGNELASLPADDLEEYSMLQTLHINGNKFTNLPADISRAKKLTVFDCGSNSLKYNIANVPYDWNWNLNPNLRYLNLSGNRRLEIKQSSVPTAAQNREQYTDFGRLTNLRVLGLMDVTVLNSTLPDQSEDRRVRTSGSLAGYMPYGMADTLGSKNEHLSTIDLVVPRFNSNDSETLLGLFDGQALSSGGSKIAKYLQENFGHIFSQELRDLKNTENPADALRRSFLSLNKDLIAAGNTHTEDRSLMVHRGSTAPLVLSREDMNSGGVATIVYIQNQDLYVANVGDVQAMIIKSDSTHVMLTKKHDPADPNERTRIREAGGWVSRNGRLNDLLEVSRAFGYLDLMPAVQSAPNIEKHTIGEHDEMILIATREVWEYLPKDVLVDVTRSVRQDPDPMRAAQKVRDLAMAYGCSNKMTVQMLGVSNLKARRERSRQHKGQSMPVYASLQDDGGSSTGMRRARKARDGPLDSTLGRLDAEVPAPTGLIAIVFTDIKNSTQLWETYPEAMRTAIKNHNELMRRQLRTIGGFEVKTEGDAFMVSFPTATSALLWCFAVQCKLLHLDWPAELYNSVNCQPVYDRDNNLIFKGLSVRMGIHWGEPLSEPDPVTRRMDYYGPMVNKASRISACADGGQIAVSSDFIAEIQRCLEHYQEPTSTAVDLNEDSFATAIRSELRSLSGQGFEVKDMGEKKLKGLENPEFIYSLYPHALSGRIETHSKHEKEQAQDLREIRPAILSPGSELSVEPDDIWSLWRVALRLEMLCSMLEDNSKALQPPETGLLDRMRQRGGEVSEDFLVNFLDHQVSRIETCINTIYMRHLVSQSSIGSNFGALRGPMDEVLKVVAEQFQLVAEYKARYGDLRA
What is the function of this protein?
Plays essential roles in regulation of cellular metabolism by catalyzing the synthesis of a second messenger, cAMP.
What are the official names of this protein?
Adenylate cyclase, ATP pyrophosphate-lyase, Adenylyl cyclase.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-3 family.
Protein: MURA_DEIGD
Sequence: MQLTPLHIQGGRNLSGEIAIQPSKNAALPIIVASLLSSEPVTLHGVPRLSDVYTILELAHHIGTRHVWTGPNSLTLHTPEILNTDAPYALVSKMRASFIMMGALLARAGEATVSMPGGCAFGYRPVDQHVKAFRALGVHIVEEGGNFEARREGSLNGAFVFELLTVGGTQNAILASVLGDGVVTLENASIDTDVVDLINFLNSLGAQIQGGGTNTLTIRGVRALRGGEYRIIPDRIEAGTFMIAAAATRSRLTLTNVRPDHLRAVSSKLMEMGVDILETEGRLIVDARDRELKPVNVTTQSFPGFPTDVQPQMSALLATVPGTSVVQDPVYPDRLTHVAELHRMGANITVSGYTQVIQGGTLHAAPVKAADLRAGAALFIAALTTEGETVIEGVQYLNRGYERLAERLRSIGANAWQPQPVLASAMD
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POPB_RALSO
Sequence: MSHSKIKAGGHGSSGIGNDFTPAKTPAPATPAPQSQQVNDLLGRGVGNALNKSNLGSDSQTWTPGSTMVSLKSRSSSSHKPDTGGDTKPDSTSGGKRKRDDETDPNAETEGGKKKKKRDDENDSSQAGGAGSSAGSSGSPEDALMNIALQRAIQRQTQTRQKMQEAMKIKDDDD
What is the function of this protein?
Probably involved in host-pathogen interactions.
What are the official names of this protein?
Protein PopB.
What are the subcellular locations of this protein?
Secreted.
Protein: CAPSD_HEVCH
Sequence: MRPRPILLLLLMFLPMLPAPPPGQPSGRRRGRRSGGSGGGFWGDRADSQPFAIPYIHPTNPFAPDVTAAAGAGPRVRQPARPLGSAWRDQAQRPAAASRRRPTTAGAAPLTAVAPAHDTPPVPDVDSRGAILRRQYNLSTSPLTSSVATGTNLVLYAAPLSPLLPLQDGTNTHIMATEASNYAQYRVVRATIRYRPLVPNAVGGYAISISFWPQTTTTPTSVDMNSITSTDVRILVQPGIASEHVIPSERLHYRNQGWRSVETSGVAEEEATSGLVMLCIHGSLVNSYTNTPYTGALGLLDFALELEFRNLTPGNTNTRVSRYSSTARHRLRRGADGTAELTTTAATRFMKDLYFTSTNGVGEIGRGIALTLFNLADTLLGGLPTELISSAGGQLFYSRPVVSANGEPTVKLYTSVENAQQDKGIAIPHDIDLGESRVVIQDYDNQHEQDRPTPSPAPSRPFSVLRANDVLWLSLTAAEYDQSTYGSSTGPVYVSDSVTLVNVATGAQAVARSLDWTKVTLDGRPLSTTQQYSKTFFVLPLRGKLSFWEAGTTKAGYPYNYNTTASDQLLVENAAGHRVAISTYTTSLGAGPVSISAVAVLAPHSALALLEDTMDYPARAHTFDDFCPECRPLGLQGCAFQSTVAELQRLKMKVGKTREL
What is the function of this protein?
Forms an icosahedral capsid with a T=1 symmetry and a 34 nm diameter.  The capsid is composed of 60 copies linked to each other (By similarity).  Binds to the 5' end of the genomic RNA to mediate genome encapsidation (By similarity).  Binds to heparin surface proteoglycans (HSPGs) to mediate viral entry (PubMed:19812150).  Additionally, the interactions with host ASGR1 and ASGR2 facilitate viral infection of hepatocytes (PubMed:27155063).  Inhibits IFN production by blocking host TBK1-induced IRF3 phosphorylation (By similarity).  The nuclear form probably modulates host gene expression (By similarity).
What are the official names of this protein?
Pro-secreted protein ORF2, Protein ORF2, pORF2.
What is the protein family that this protein belongs to?
Belongs to the hepevirus capsid protein family.
What are the subcellular locations of this protein?
[Isoform Secreted protein ORF2]: Secreted. SUBCELLULAR LOCATION: [Isoform Capsid protein ORF2]: Virion. Host cytoplasm. Host endoplasmic reticulum. Host Golgi apparatus. Host cell surface.
Protein: COX8_SCHPO
Sequence: MLRYSLQARSALRGVRFSSSHSAPKPGSTIPFYINKKPLPTLLYFGTFGVIFSIPFIVVKYHNRNL
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase polypeptide VIII, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase VIIc family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: RIMM_LISIN
Sequence: MEKMYNVGKIVNTHGLIGEIRVIATTDFPEERFQVGNTVYLFEKNSKKPEKLIIRSHRKHKNFDLLMFEGLTGIHQVERMKEGVLKIKEAQLTDLEENEFYFHEIIGCTVVTTDGEELGEITEILTPGANDVWVVKGADKKEKLIPYIADVVKDINTNDKKITIEVMEGLLD
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4095_ARATH
Sequence: MEAEKETEQEGNLTVMKLPVLPTKPNTHSHSMSSPIHSSISASVPFSWEEEPGKPKQHSTSSSSSSSSSPLTSYSSSPFETHKSLELPPRLHLLEKDGGSVTKLHSPITVFDGPYSMTTSKRMDSPSFRMMVKGSADCYGSFRSDIDGDLEDLEVGSKQQENLSSGSLAVVKKRGRLGFFGFRRRRALKGKTEFGRGSYVFPSSVDRESEYSRKEEEEEKEDKRFGYDDTDGISCSQSSRFCDVKISSISRTGSFSTLPAPPSSSSKSHFWTNVYAGLKQVVPWKSKKTTV
What are the official names of this protein?
Uncharacterized protein At4g00950.
Protein: HPH2_YEAST
Sequence: MQNAQIKSSSKGSGIDGTDRNSKDGVEKRPLEDVKQMIDAGTPDVGHKSTVETKPNVGWQASHSNLAALHEKEQKYEMEHHHARHKLHRQVIPDYTSASTAMFSDCMFNAAPDKVRSLSTMKSSGLSPKHPFNVVATFKGPFPQHSVESKPLDGGYSAKDHFPSFKMLQAQQHPAHRHYKDNDKYGLKSPSRSFVKDKKRLVHRFLKSMEPSSSGQSKDSSALAPAFDPILPNVISKPSKRPTHHSHSSDGSSSTQTDISLQSLLYHDLESSPKKHVSPSRPPSVASESSPAVANPIGLSPKDACNASFSQSSSSSLSSSSSSSSSTSFSQSVAVDPLEPPGNITYSSSNLSLNSDELDYYQRHIGLQLQQTEALLKHSLKDEVLKDENDLVKNIANFDKIVKELRDLRSRTIGWKELVEEDYLMNLKQDFDKENPESFEARLSDTINTNVAKLQDLEKRMASCKDRLASRKEVMRKMESLLSLENSLMISKKNVTFASKYRNEALDIVFLIIIIVICYTFKHLVSHK
What is the function of this protein?
Required for growth under high NaCl, alkaline pH and cell wall stress.
What are the official names of this protein?
Protein HPH2, Functionally related to TCP1 protein 2, High pH protein 2.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Note=Punctate foci at the endoplasmic reticulum membrane.
Protein: RS13_MICAN
Sequence: MARIAGVDLPRDKRVEIALTYLYGVGLSRSQEVLSATGVNPDTRVKDLSDEDVAALRTYIETNYQIEGDLRRWEAMNIKRLADIGTYRGRRHRLGLPVRGQRTRTNARTRRGRRVTVAGKKKAPSKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: ALAE_CERS4
Sequence: MRLFIIDTVATVIFFTAVATFSELLIAGMAPSEVLATRLLMVPVMVLTGRPYTRWRDWLVRRTAPRNRWSAFLTDILAFLSFQAPVYGATLLIAGASFAEAGTAIGSAIILMILLARPFGLFVEWTRSLFGVELS
What is the function of this protein?
Exports L-alanine.
What are the official names of this protein?
L-alanine exporter AlaE.
What is the protein family that this protein belongs to?
Belongs to the AlaE exporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYJ2B_RAT
Sequence: MNGRVDYLVSEEEINLTRGPSGLGFNIVGGTDQQYVSNDSGIYVSRIKEDGAAARDGRLQEGDKILSVNGQDLKNLLHQDAVDLFRNAGYAVSLRVQHRLPVQNGPIVHRGDGEPSGVPVAVVLLPVFALTLVAVWAFVRYRKQL
What is the function of this protein?
Regulates endocytosis of activin type 2 receptor kinases through the Ral/RALBP1-dependent pathway and may be involved in suppression of activin-induced signal transduction.
What are the official names of this protein?
Synaptojanin-2-binding protein, Mitochondrial outer membrane protein 25, NPW16.
What are the subcellular locations of this protein?
Mitochondrion outer membrane.
Protein: NAGZ_ECO27
Sequence: MGPVMLDVEGYELDAEEREILAHPLVGGLILFTRNYHDPAQLRELVRQIRAASRNHLVVAVDQEGGRVQRFREGFTRLPAAQSFAALLGMEEGGKLAQEAGWLMASEMIAMDIDISFAPVLDVGHISAAIGERSYHADPQKALAIASRFIDGMHEAGMKTTGKHFPGHGAVTADSHKETPCDPRPQAEIRAKDMSVFSSLIRENKLDAIMPAHVIYSDVDPRPASGSPYWLKTVLRQELGFDGVIFSDDLSMEGAAIMGSYAERGQASLDAGCDMILVCNNRKGAVSVLDNLSPIKAERVTRLYHKGSFSRQELMDSARWKAISARLNQLHERWQEEKAGH
What is the function of this protein?
Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.
What are the official names of this protein?
Beta-hexosaminidase, Beta-N-acetylhexosaminidase, N-acetyl-beta-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEX16_BOVIN
Sequence: MEKLRLLGLRYQEYVTRHPAATAQLETAVRGLSYLLAGRFADSHELSELVYSASNLLVLLNDGILRKELRKKLPMSLSQQRLLTWLSVLECVEVFMEMGATKVWGEVGRWLVIALIQLAKAVLRMFLLIWFKAGLQTSPPIVPLDREIQAQSRDGDHSSGSQEQSYVGKRSNRVVRTLQNTPSLHSRHWGAPQQREELGVAPTPLGLQETIAESLHIARPLLHLLSLGLWGQRSWTPWLLSGVVDVTSLSLLSDRKGLTRRERLELRRRTILLLYYLLRSPFYDRFSEAKILFLLQLLADHVPGIGLVTRPLMDYLPNWQKIYFYSWG
What is the function of this protein?
Required for peroxisome membrane biogenesis.  May play a role in early stages of peroxisome assembly.  Can recruit other peroxisomal proteins, such as PEX3 and PMP34, to de novo peroxisomes derived from the endoplasmic reticulum (ER).  May function as receptor for PEX3 (By similarity).
What are the official names of this protein?
Peroxisomal membrane protein PEX16, Peroxin-16, Peroxisomal biogenesis factor 16.
What is the protein family that this protein belongs to?
Belongs to the peroxin-16 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Multi-pass membrane protein.
Protein: SSRP_SYMTH
Sequence: MARAKAEIQPVAENRKARHDYFVEETYEAGIVLVGSEVKSCRAGRVNLRDAYAQIKDGEIFLLNCHISPFEQANRFNHEPLRPRKLLMHKSEIHRLYGKVREKGFTLVPLRLYFNQKGKVKVELALAKGKRAYDKRDDIAAREAKREMARALRGRYDD
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: SCX3_MESMA
Sequence: VRDAYIAKPENCVYECATNEYCNKLCTDNGAESGYCQWVGRYGNACXCIKLPDRVPIRVWGKCHG
What is the function of this protein?
Binds to sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking neuronal transmission.
What are the official names of this protein?
Neurotoxin BmK-M3, BmK3, BmKM3, Bmk M3, BmK III, BmKIII, BmK-III.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: VDAC2_RAT
Sequence: MAECCVPVCQRPICIPPPYADLGKAARDIFNKGFGFGLVKLDVKTKSCSGVEFSTSGSSNTDTGKVSGTLETKYKWCEYGLTFTEKWNTDNTLGTEIAIEDQICQGLKLTFDTTFSPNTGKKSGKIKSAYKRECINLGCDVDFDFAGPAIHGSAVFGYEGWLAGYQMTFDSAKSKLTRSNFAVGYRTGDFQLHTNVNNGTEFGGSIYQKVCEDFDTSVNLAWTSGTNCTRFGIAAKYQLDPTASISAKVNNSSLIGVGYTQTLRPGVKLTLSALVDGKSFNAGGHKLGLALELEA
What is the function of this protein?
Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules (By similarity).  The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV (By similarity).  The open state has a weak anion selectivity whereas the closed state is cation-selective (By similarity).  Binds various lipids, including the sphingolipid ceramide, the phospholipid phosphatidylcholine, and the sterol cholesterol (By similarity).  Binding of ceramide promotes the Binding of ceramide promotes the mitochondrial outer membrane permeabilization (MOMP) apoptotic pathway (By similarity).
What are the official names of this protein?
Voltage-dependent anion-selective channel protein 2, VDAC-2, B36-VDAC, Outer mitochondrial membrane protein porin 2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic mitochondrial porin family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane. Membrane. Note=May localize to non-mitochondrial membranes.
Protein: PSTA_MYCLE
Sequence: MNLDTLDRPVKAVVLRPISVRRRIKNNVATMFFFTSFLIALVPLVWLLSVVVARGFYAVTRFDWWTHSLRGVMPEEFAGGVYHALYGSLVQAVVAAIMAVPLGSMTAVYLVEYGSGPFVRVTTFMVDVLAGVPSIVAALFIFCLWIATLGFQQSAFAVSLALVLLMLPVVVRSTEEILRLVPDELREACYALGIPKWKTIVRIVFPIATPGIISGVLLSIARVIGETAPVLVLVGYSRSINFDIFDGNMASLPLLIYTELTNPEYAGFLRVWGAALTLIILVAGINLFGAAFRFLATRRCSGCR
What is the function of this protein?
Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Phosphate transport system permease protein PstA.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS13_NEOSM
Sequence: MRFLGVNLPDNKAVVVALTYLYGIGLPTARKICSSLAIDGSAKLPDLEQEQLNSIMAYIKNDIPFEGELRKSVAFSIKHLVDIKCYRGVRHRKNLPVRGQRTRTNARTRKGKVRVPIAAKKRV
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: RL17_FRATH
Sequence: MRHRKQGRKFGRTSSHRKAMFKNMSASLINHELIKTTLPKAKELRTIVEPLVTLAKREHKLRQELDTNSNEFKAQSVALRRQAFDFLRNKAAVTKLFEEFGARYAERAGGYTRILKCGYRFGDKAPMAFIELVDRPQVEEAADEE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: RAPA_VIBVU
Sequence: MAFALGQRWISDTESDLGLGTVVALDARTVTLMFAASEENRVYASNDAPVTRVVFNVGDVVECQEGWSLKVEQVVEENGLYTYLGTREDTEETGVALREIFLSNQIRFNKPQDKMYAGQIDRMDNFVLRYRALKNQYEQHRSPMRGLCGMRAGLIPHQLYIAHEVGRRHAPRVLLADEVGLGKTIEAGMIIHQQVLLGRAERILIVVPETLQHQWLVEMMRRFNLHFSIFDEERCVEAFAESDNPFDTQQYVLCSLDFLRKSRKRFEQALEAEWDLLVVDEAHHLEWSQDKPSRGYQVVEGLAERTPGVLLLTATPEQLGRESHFARLRLLDSDRFYDYAAFVEEEAQYAPVADAITALFSGVKLADEAKNQITELLSEQDVEPLFRIIESNADEESKAIARQELIDNLMDRHGTGRVLFRNTRAAIKGFPVRNVHLLPMPIPTQYTTSMRVSGMIGGKLAPEARAMKNLYPEEIFQEFEGEESSWWQFDCRVNWLLEKLKAQRSEKVLVIASRASTALQLEQALREREGIRATVFHEGMSILERDKAAAYFAQEEGGAQVLICSEIGSEGRNFQFANQLVMFDLPFNPDLLEQRIGRLDRIGQKRDIDIHVPYLQGTAQEVLARWFNEGLNAFAETCPTGRTVYDQVSDQLIEMLASGSNEALDDVIAESAKLNQALKADLEQGRDRLLEMHSNGGEKAQQIVAEIAAKDGDTNLVSFALSLFDTIGLNQDDKGENAIVVTPSEHMMVPSYPGLPYEGATITFDRDTALSREDMHFISWEHPMIQGGIDLLMSEGVGTCAVSLLKNKALPVGTLLLELIYAVDAQAPKRSGIGRFLPRTPIRLMMDARGNDLSGQVEFESFNRQLSPVNRHLASKLVSSVQNDIHRLIEAGDQLVVENVEAIRQQAQQEMQQSLNSELERLQALKAVNPNIRDEEIEAIDAQIKELNGYISKAQFQLDSLRLIVVSHN
What is the function of this protein?
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations.  Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA.  Does not activate transcription on linear DNA.  Probably not involved in DNA repair.
What are the official names of this protein?
RNA polymerase-associated protein RapA, ATP-dependent helicase HepA.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
Protein: UNG_ECOL6
Sequence: MANELTWHDVLAEEKQQPYFLNTLQTVASERQSGVTIYPPQKDVFNAFRFTELGDVKVVILGQDPYHGPGQAHGLAFSVRPGIATPPSLLNMYKELENTIPGFTRPNHGYLESWARQGVLLLNTVLTVRAGQAHSHASLGWETFTDKVISLINQHREGVVFLLWGSHAQKKGAIIDXQRHHVLKAPHPSPLSAHRGFFGCNHFVLANQWLEQRGETPIDWMPVLPAES
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_LISW6
Sequence: MQTYDAGTFDVIVVGAGHAGVEAGLASGRMGAKTLMLTINLDMVAFMPCNPSVGGPAKGVVVREIDALGGEMGRNTDKTYIQMRMLNTGKGPAVRALRAQADKWDYQHEMKHTIEKEENITLRQGLVDHLVIEDGVCKGVITNSGAIYYAKTVVITTGTFSRGEIIVGELRYSSGPNNQQPSVKLSEHLEELGFELRRFKTGTPPRVKSSTIDYSKTEEQPGDDHPRAFSFDTVDMMLDQLPCWLTYTNETTHEIIQANLHRSPMFTATKKGTGARYCPSIEDKIVRFSDKPRHQIFLEPEGKNTEEVYVQGLSTSLPEEVQREMLRTIPGLENVEMMRVGYAIEYDAVMPDQLWPSLETKLVEGLFTAGQINGTSGYEEAAGQGLMAGINAARKVFDKEPIILGRDQAYIGVLIDDLVTKGTEEPYRLLTSRAEYRLLLRHDNADLRLTEIGHEIGLISDERYERFLAKQSAIEAEKERLQKTRIKPTAEVQAMLKEIGSGELKDGILAADLLRRPEITYDKIAQIVSRETFITDEIAEQVEIQVKYEGYIQKSNLQVEKMKRMEDKKIPENIDYDAISGLATEALEKLKKIEPLSIAQASRISGVNPADISILLVYIEQGKIAKISK
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_LEVBA
Sequence: MTLTRHQIRERAFQMLFALNANPEADHDALYQRVLTDDPNQLVPVPDYLATLVNGVLAHQSELDAQIDQYLSTGWQLKRIAKTDLVILRMAFYEIEHVDDVPNRVAVNEALELAKNFSDDRSRRFINGVLAHTLDDETDTQA
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: OSTB_MOUSE
Sequence: MDHSAEKAAANAEVPQELLEEMLWYFRAEDAAPWNYSILVLAVLVVMTSMFLLRRSILANRNRKKQPQDKETPEDLHLDDSIMKENNSQVFLRETLISEKPDLAPGEPELKEKDSSLVFLPDPQETES
What is the function of this protein?
Essential component of the Ost-alpha/Ost-beta complex, a heterodimer that acts as the intestinal basolateral transporter responsible for bile acid export from enterocytes into portal blood (PubMed:15563450, PubMed:16317684, PubMed:17650074, PubMed:22535958).  The Ost-alpha/Ost-beta complex efficiently transports the major species of bile acids (taurocholate) (PubMed:16317684, PubMed:17650074, PubMed:22535958).  Taurine conjugates are transported more efficiently across the basolateral membrane than glycine-conjugated bile acids (PubMed:16317684).  Can also transport steroids such as estrone 3-sulfate and dehydroepiandrosterone 3-sulfate, therefore playing a role in the enterohepatic circulation of sterols (By similarity).  Able to transport eicosanoids such as prostaglandin E2 (By similarity).  Modulates SLC51A glycosylation, membrane trafficking and stability activities (PubMed:15563450).
What are the official names of this protein?
Organic solute transporter subunit beta, OST-beta, Solute carrier family 51 subunit beta.
What is the protein family that this protein belongs to?
Belongs to the OST-beta family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=Mainly restricted to the lateral and basal membranes of ileal enterocytes.