PharMolix/UniProtQA huggingface dataset:
Protein: LHS1_CANGA
Sequence: MKLSILFLFAIAVQAAFLGIDYGQQSIKAMVVSPKAMMEIVLTPEAKRKDTSGICIRNVNGVLERHYGNSIGSLVTRFPQNTAMHLRSLLGKSMNDKDTIESYLRENPGANLTSTTRNTIAITIDGVEYPVEQLVAMNLQEIIDRANQHIKETDTTGIDFVEQVGIAIPEQFNQAQRQALLDALALTSVKDEAVLVSDGLSVAIDYALKRPDLEINVPQYYIVFDVGTSAAKATLFSLTQPEDLSSPIKIEIGAFDSEATVGGSKFIAAIADIVEDKFLEKNTKITRKSLVENPRARAKIIQAAEKAKLVLSANNEAIISIESLVDDIDFRTTIARSEFQDIFEDNKHTVVKAIKGAIGNQLWDDNISLEDISGVILSGGSSRVPMVQEEIAKLVGEEKILKNVNADETVINGATLKGLKYFGSFKTKPLDITERSLFDYSVEMSGESSSKTVFEKGTKFPNESSILYKAPKKFGKELKFDLFESDTRILSNIVDTTVSSKNWTSACKKGQLYLNVTFDLDSNRVFKIKDITVLCDSDGNAKEEEFEFIDVINDVTKATDVMPLSNAEIRQLSNAITSWNRKDRERKRVQESLNVLEAELYDCRSFIEEFEEKLGEEEFETLKSFTAFVKEKLEYLEDNSADMSKKDIEKLVRETRSQRDTLSRFYNSLDAALGSKDFQKLVDTASKSIKKYKEIESKNLADLENKAEKFNVIGLNVTEKYNSILSKMSFSSIRRSSEENIKTLAGLIDEVNESIKSKAIDDESLENLIKTKLAFEELINTLDLENRQWTYQHQLVMKELKKMYNKKMKAIKKQEKQNENEENGDDEGDDEDETKTKKYLKEATSSGDSSTIKEEDSTGSNEAGNKGDEEDEEEEEDDSSAGNVFDDEL
What is the function of this protein?
Chaperone required for protein translocation and folding in the endoplasmic reticulum.
What are the official names of this protein?
Heat shock protein 70 homolog LHS1.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: PURA_SALCH
Sequence: MGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMKELEDRGIPVRERLLLSEACPLILDYHVALDNACEKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAEKLKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEYGATTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLDVLDGLKEVKLCVAYRMPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPFDA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LAX1_BOVIN
Sequence: MDVTTSAWSETTRRISEPSTLQGTLGSLDKAEDHSSSIFSGFAALLAILLVVAVICVLWCCGKRKKRQVPYLRVTIMPLLTLPRPRQRAKNIYDLLPRRQEELGRHPSRSIRIVSTESLLSRNSDSPSSEHVPSRAGDALHMHRAHTHAMGYAVGIYDNAMRPQMCGNLAPSPHYVNVRASRGSPSTSSEDSRDYVNIPTAKEIAETLASASNPPRNLFILPGTKELAPSEEIDEGCGNASDCTSLGSPGTENSDPLSDGEGSSQTSNDYVNMAELDLGTPQGKQLQGMFQCRRDYENVPPGPSSNKQQEEEVTSSNTDHVEGRTDGPETHTPPAVQSGSFLALKDHVACQSSAHSETGPWEDAEETSSEDSHDYENVCAAEAGARG
What is the function of this protein?
Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells.
What are the official names of this protein?
Lymphocyte transmembrane adapter 1, Membrane-associated adapter protein LAX.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type III membrane protein.
Protein: ISPH_DEIRA
Sequence: MIERIYLAKPRGFCAGVVMAIQAVEKAAVREDKPVTVYHSIVHNHTVVERLSEGGRVHFVEDLDAVDALPDSGDTVIFSAHGISPAVRERARSLGLSTIDATCPLVTKVHTEAKKYAREGYTILLIGDSAGHQEVIGTRGEAPENTILVGVLGKTGPGLNDPHAVQVPDPERLVVLTQTTLSVDDTRKTVDILKARFPALVVPPSEDLCYATKNRQDAVKNIAPNVDAFLVLTSTHSSNGMRLLELAEAECGRAYRLETAADLTRLEQNGDLGGVRSVGITSAASTPDDLVQDVVAHFRALNPALEVIEEGEWENIEFREPKKIAPTQELPRTMQ
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: N42L2_MOUSE
Sequence: MPYSEVEAKFLGPGKEQTREPCYKKLKSAADDGVSPLRGGPDIHRIQEKPRNNRVAVATINFRRRVCPQEDKTSTDVLKPLHKEMPGDKLGGSESIGSPALQDGKPSPLAKDDEIYSTSKAFIGPIYKPPEKKKCRERKSETDTFSSIDSKRRQEEKQKSNSKKLEMDTELSQFYKEIEELENENEASQGSCTEPEPSEEPIISYDWACNTLKSEEENKDLSDVLQSHCGYQEYLEDEPDYPCDEQLMPAFCETSFPSFRPEWQSMHPFVIPHDPLSSFNYFNFQRFGTPLHPSPDVFHGRDDSQMQNGCYVDSYQDGWSCLTFDQNDEYANYDVTSNNVHPFRNGCSVQDESVNNGFCEIRECWQDPSMDKHNETDRFVNQWFQEEKLNKLQKLLILLRGLPGSGKTTLSRILLGQSRDGIVFSTDDYFHHQDGYRYNVNQLGDAHDWNQNRAKQAIDQGRSPVIIDNTNTQAWEMKPYVEMAIGKGYRVEFHEPETWWKFDPEELEKRNKHGVSRKKIAQMLDRYEFQMSISIVMNSVEPTQKSIQRPLPLEGEQRWGGSLGSHSQVSIADDY
What are the official names of this protein?
NEDD4-binding protein 2-like 2, Phosphonoformate immuno-associated protein 5 homolog.
Protein: ACKA2_LISMO
Sequence: MHKIMAINAGSSSLKFQIFTMPGEEVLVKGLIERIGLPDAIFNMSFQNEKIKETRAINDHGKAVEILLEQLKAHQVINDLSEITGVGHRVAHGGEDFVTSCVVTDEVVKGIEAVTNLAPLHNPANIIGIKTFRELLPNAVSVAVFDTAFHQTIPQENFLYALPYELYEKHHIRKYGFHGTSHKYVAGKAAEVLEKPLEKLKIISCHLGNGASVCAIEAGKSVNTSMGFTPNAGLMMGTRSGTIDATIIPYLVDELGYSLDEVMHMMSNESGVLGVSGISSDFRDIEIAAKEGNSRALLTLRMFTGQICNYIGAYASAMNGCDALLFTAGVGENSPLIRQMVTEQLSYLGVTCHVTKNNAGDMIISNDNEAVKVCIIPTNEELMIARDVEKYAKQTIG
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase 2, Acetokinase 2.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROF_SCHPO
Sequence: MDKHTPLLPGDSVFSRCKTEDSRIKGYDPVISPALIQSELAASDETLAFVSDQRRQAADIIAGRDDRLLLIVGPCSLHDPVAAKEYAIRLQKEAIKHKKDLHIIMRAYLEKPRTTVGWKGLINDPDLDGSYNINKGIRVARRIFLELLETGVGIASEMLDTISPQYLADLICWGAIGARTTESQLHRELASGLSFPIGFKNATDGNIGIAIDAMNSSANPHHFLSVTKQGVVAIVTTTGNPDTHIILRGGKSGTNFDADSVAGAKAKLEECNKLPSIMIDCSHGNSSKNHKNQPKVAACIAEQVANGQKAITGVMIESHLNEGKQAIPEDDLSSMKYGVSVTDACIGWDDTTAVFEQLAAAVRSRRSH
What is the function of this protein?
Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).
What are the official names of this protein?
Putative phospho-2-dehydro-3-deoxyheptonate aldolase, 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase, DAHP synthase, Phospho-2-keto-3-deoxyheptonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class-I DAHP synthase family.
Protein: ATPE2_CERS4
Sequence: MSLTLRVTTPLAAVLEEEGLASIRAEDASGGFGLLPGHVDLLTVIEAGVLRFRRPEGPWHFCAIRGGVLRATGGRLVTVACREAVPGEDLARLEAGLKRQAEAADQAARRARGEQVRLHANAIRSLMRHLDRAPGADLSGIVEAFE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain 2, ATP synthase F1 sector epsilon subunit 2, F-ATPase epsilon subunit 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GATD_ECO57
Sequence: MKSVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVLLIP
What is the function of this protein?
Converts galactitol 1-phosphate to tagatose 6-phosphate.
What are the official names of this protein?
Galactitol 1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: RUTC_ECO45
Sequence: MPKSVIIPAGSSAPLAPFVPGTLADGVVYVSGTLAFDQHNNVLFADDPKAQTRHVLETIRKVIETAGGTMADVTFNSIFITDWKNYAAINEIYAEFFPGDKPARFCIQCGLVKPDALVEIATIAHIAK
What is the function of this protein?
Involved in pyrimidine catabolism.  Catalyzes the deamination of 3-aminoacrylate to malonic semialdehyde, a reaction that can also occur spontaneously.  RutC may facilitate the reaction and modulate the metabolic fitness, rather than catalyzing essential functions.
What are the official names of this protein?
3-aminoacrylate deaminase RutC, 3-AA deaminase.
What is the protein family that this protein belongs to?
Belongs to the RutC family.
Protein: YIDC_XYLF2
Sequence: MNQTRVLLIFSWLTVATLLWMDWSKNKNETLEISASHNLGVDSNLELEHAVPQIHAGAVPLQKDSQLIAAAPKVPVINVTTDVLQLKLDGFSILAADLLRFPQSKDRGAKPIKLLTDDPNYPYSATTGWVSQSNSPVPNLSTFLPEQPDVSYKLANDQNRLVVPFIWTAANGVSIRRTFTFERGRYAILIRDEIRNSGETPWNAYVFRKLSRVPIPNILNRAMTNPDSFSFNGAVWYSEKGGYERRAFKDYMNDGGLNREIGGGWIALLQHHFFTAWIPQKDQASLYLLAQNGSRDIAELRGPAFTVAPGQTTTTEARLWVGPKLVEQITKEHVKGLDRVVDYSRFQLMALIGQGLFWILSHLNSLLHNWGWAIVGLVVLLRIAMYPLSASQYKSAAKMRKFQPRLQQLKERYGEDRQKFQQAMMELYKKEKINPMGGCFPILIQMPIFFALYWVLVESVELRQAPWLGWIQDLTTRDPYFILPLLNIVIMWATQKLTPTPAGMDPIAGKMMQVMPLIFGVMMAFVPSGLALYWVINGGLNLLIQWWMIRQHADFSRKRSRENIK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SPB11_MOUSE
Sequence: MDPITTASTEFCLDVFKELSSNNVGENIFFSPLTTFYALSMLLLGTRGKSAEQMEKVLHYDSFSGVLKAKTKNSSECSQVGVMHPDFRALISHINQQNSLSVANRIYGTRSISFHKQYVRCCEKLYQAKLQTVDFELSTEETRKSINAWVKNKTNGKITNLFAKGTIDPSSVMVLVSAIYFKGQWQNKFQKRETVKAPFHMGVGKSAVVNMMYQTGTFKLAIIKEPEMQVLELPYANNKLRMIILLPVGTASVSQIEKHLNVKMLREWTNPSNMVEREVDVHIPKFSLSVKYDLNTLLKSLGMRDIFNVANADLSGMSPDKGLYLSKVVHKSYVDVNEEGTEAAAATGESISVKRLPVTVQFTANCPFLFFIWDESGNILFAGKFASP
What is the function of this protein?
Inhibitor of serine proteases.  Has moderate inhibitory activity for trypsin-like peptidases, but also some activity with cysteine peptidases, cathepsin L, K, and V, and the serine peptidase, tryptase gamma.
What are the official names of this protein?
Serpin B11.
What is the protein family that this protein belongs to?
Belongs to the serpin family. Ov-serpin subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MACB_BARHE
Sequence: MKAKQADAVLVLENIVRKFPAGETFVTVLKDINLTIKRGEMVAIVGASGSGKSTLMNILGCLDRPTFGRYWISGKETASLSADELSALRRNHFGFIFQRYHLLNELTALGNVEIPAVYAGYAPEVRRKRAEDLLTRLGMRDRIHHRPNQLSGGQQQRVSIARALMNNAEVILADEPTGALDKKSGQEVLRILDELHQEGRTIIMVTHDMQVAERADRIIEISDGEIIADNVSKVAKTKTDSQALYGKQVLKDQKTLGFFRSFAERFREAFVMALLAMNAHRMRTFLTMLGVIIGIGAIIAMVALGNGTREKILENFKSLGSNTLTILPGKSLSDPQAEKITSLVEADAEALSKLPYVSGVTPQMSASSTIRFGSVEADVVIAGVGEQYFQTQGLNAVQGRLFDQKSVHDRAIDLVIEKEALAVLFPHSHESPLGKVVHVGNVPVRIVGVIDPQHNGGTSSTLQVYLPYTTVQTRFLGTTQVRAITVKIADTVDSNLAETMVRRFLIMRHGEEDFFIRNSQLFRDRIMESTHILTLLVSSIAAISLIVGGIGVMNIMLVTVSERINEIGVRMAVGARQSDILQQFLIEAILVCVIGGGLGILFGMSIGGLFLLFKAPIHLIYTIDSIILSLTFSTLIGVCFGFSPARQASRLDPVVALSRD
What is the function of this protein?
Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation.  Confers resistance against macrolides.
What are the official names of this protein?
Macrolide export ATP-binding/permease protein MacB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PVA_PLAFA
Sequence: ETGESKETGESKETGESKETGESKETGESKETGESKETGESKETGESKETGESKETGESKETGESKETGESKETGESKETGESKETGESKETGESKETGESKETRIYEETKYNKITSEFRETENVKITEESKDREGNKVSGPYENSENSNVTSESEETKKLAEKEENEGEKLGENVNDGASENSEDPKKLTEQEENGTKESSEETKDDKPEENEKKADNKKKKK
What are the official names of this protein?
Processed variable antigen.
Protein: RL16_YERP3
Sequence: MLQPKRTKFRKMHKGRNRGLAQGTDVSFGEFGLKACGRCRLTARQIEAARRAMTRAIKRQGKVWIRVFPDKPITEKPLEVRMGKGKGNVEYWVALIQPGKVLFEMAGVPEETAREAFKLAAAKLPVGTTFVTKTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: PDAD_METAR
Sequence: MRQGLVPKKVFFTSGVGRHREMLESFEMALRDAGIEKFNLVTVSSILPPDCEIVQKSEGLPSLYPGEIVFTVMSRNSSNEPSRRIAASIGCAIPKDPVKNFGYLSEHHSYGETEQYAGMYAEKLAENMLFTWTKEKPGKTMNISKTAEVDDEGNWTTVISAAVFIL
What are the official names of this protein?
Pyruvoyl-dependent arginine decarboxylase, PvlArgDC.
What is the protein family that this protein belongs to?
Belongs to the PdaD family.
Protein: THYX_MYCTA
Sequence: MAETAPLRVQLIAKTDFLAPPDVPWTTDADGGPALVEFAGRACYQSWSKPNPKTATNAGYLRHIIDVGHFSVLEHASVSFYITGISRSCTHELIRHRHFSYSQLSQRYVPEKDSRVVVPPGMEDDADLRHILTEAADAARATYSELLAKLEAKFADQPNAILRRKQARQAARAVLPNATETRIVVTGNYRAWRHFIAMRASEHADVEIRRLAIECLRQLAAVAPAVFADFEVTTLADGTEVATSPLATEA
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
What are the official names of this protein?
Flavin-dependent thymidylate synthase, FDTS, FAD-dependent thymidylate synthase, Thymidylate synthase ThyX, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase ThyX family.
Protein: THA_BPCA1
Sequence: MHFNELRISQDNRFLIIDVSVDNQDYFEDVLLDSIVIDTQDTFVMNGPSDNPLYIYNVEDAYDLTYSLPEQCNCNPVRVEEDESYCFTYGTQQMKNVRLELNIQDLKVSPCSTMFFVYVKSKGTPSTDTPCGFDKDQILGTVINLQPIYKQTLKYLKEVECDCNIPKGFIDMILKLKAIELCVRTGNYPQAIKYWNKFFIKNNCKSPTSNCGCYG
What is the function of this protein?
Forms the tail hub together with tail hub protein B (THB).
What are the official names of this protein?
Tail hub protein A, THA, Gene product 38, gp38.
Protein: SYFB_PONAB
Sequence: MPTVSVKRDLLFQALGRTYTDEEFDELCFEFGLELDEITSEKEIISKEQGNVKAAGASDVVLYKIDVPANRYDLLCLEGLVRGLQVFKERIKAPVYKRVMPDGKIQKLIITEETAKIRPFAVAAVLRNIKFTKDRYDSFIELQEKLHQNICRKRALVAIGTHDLDTLSGPFTYTAKRPSDIKFKPLNKTKEYTACELMNIYKTDNHLKHYLHIIENKPLYPVIYDSNGVVLSMPPIINGDHSRITVNTRNIFIECTGTDFTKAKIVLDIIVTMFSEYCENQFTVEAAEVVFPNGKSHTFPELAYRKEMVRADLINKKVGIRETPENLAKLLTRMYLKSEVIGDGNQIEIEIPPTRADIIHACDIVEDAAIAYGYSNIQMTLPKTYTIANQFPLNKLTELLRHDMAAAGFTEALTFALCSQEDIADKLGVDISATKAVHISSPKTAEFQVARTTLLPGLLKTIAANRKMPLPLKLFEISDIVIKDSNTDVGAKNYRHLCAVYYNKNPGFEIIHGLLDRIMQLLDVLPGEDKGGYVIKASEGPAFFPGRCAEIFARGQSVGKLGVLHPDVITKFELTMPCSSLEINIGPFL
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YEIS_SHIFL
Sequence: MDVQQFFVVAVFFLIPIFCFREAWKGWRAGAIDKRVKNAPEPVYVWRAKNPGLFFAYMVAYIGFGILSIGMIVYLIFYR
What are the official names of this protein?
Uncharacterized protein YeiS.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SYDND_SULSY
Sequence: MIDQLREFKRDYYCGDLNESNIGDEVRLLGWVDTVRDHGGVIFINLRDREGIVQVVFDPSKIGEELYNKAKKLKSEYVIGVRGRVYRRPAGTENPKMKTGNIEVAGEELLILNTSKALPFPIEDNIKVSEEVRLKYRYLDLRRPSMQRNIILRHEVYQAVREFLAGNGFIEVETPMLTKSTPEGARDFLVPSRLEKGKFYALPQSPQLFKQILMVAGLERYFQIAKCFRDEDLRADRQPEFTQIDLEMSFVTEDDVMTLAESLIQYVYKKVLGIDIKIPFRRMSYEEAINKYGTDKPDLRYGLELIDITDLAKEVEFKVFNDVAKSGGLVKGINIKGGSKFSRKEIDELTEYAKKFGAKGMAWVKLENGEATSPILKFFTEEQKQKLFSLMDAKDGDLLIFIADKKDITHKVLGFLRKHIAEKMNLIDNSKLEFLWVVDFPLFEWDEEENRLVAIHHPFTSPKDEDIDRLDEALNSPEIALSFKSKAYDMVLNGEEIGGGSIRIHTPYIQEKVFQLLNISEEEAKEKFGFLIEALSYGAPPHGGLAFGLDRILALMTGSESIRDVIAFPKTQKGICPLTGAPDYVSEKQLKEVGIKVEVDEE
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBP12_HUMAN
Sequence: MEILMTVSKFASICTMGANASALEKEIGPEQFPVNEHYFGLVNFGNTCYCNSVLQALYFCRPFREKVLAYKSQPRKKESLLTCLADLFHSIATQKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRLPNGNIDNENNNSTPDPTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHDFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRD
What is the function of this protein?
Deubiquitinating enzyme.  Has almost no deubiquitinating activity by itself and requires the interaction with WDR20 and WDR48 to have a high activity (PubMed:19075014, PubMed:27373336).  Not involved in deubiquitination of monoubiquitinated FANCD2 (PubMed:19075014).  In complex with WDR48, acts as a potential tumor suppressor by positively regulating PHLPP1 stability (PubMed:24145035).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 12, Deubiquitinating enzyme 12, Ubiquitin thioesterase 12, Ubiquitin-hydrolyzing enzyme 1, Ubiquitin-specific-processing protease 12.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. USP12/USP46 subfamily.
Protein: ENO_BURCM
Sequence: MSAIVDIIGREILDSRGNPTVECDVLLESGTMGRAAVPSGASTGSREAIELRDGEAGRYNGKGVLKAVEHINTEISEAIMGLDASEQAFLDKTLLELDGTDNKSRLGANAMLAVSMAVAKAAAEEAGLPLYRYFGGSGAMQLPVPMMNIVNGGAHANNSLDIQEFMIVPVSQPTFREALRCGAEVFHALKKILSDRGMSTAVGDEGGFAPNFGSNDECLSTILQAIEKAGYRAGEDVLLALDCAASEFYHDGKYQLAGEGLQLSSAEFTDYLATLADKFPIVSIEDGMHESDWEGWKLLTERLGKKVQLVGDDLFVTNTRILKEGIEKGIANSILIKINQIGTLTETFAAIEMAKRAGYTAVISHRSGETEDSTIADIAVGLNAGQIKTGSLSRSDRISKYNQLLRIEEDLGDIASYPGKSAFYNLR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: GCSPA_PARL1
Sequence: MRYLPLTENDRREMLGVIGAKSVDELFRDVPERARREGLVDLPRRQGELEVERMLGRMAAKNTPAASVPFFVGAGAYRHHVPAAVDHLIQRSEFLTSYTPYQPEITQGTLQYLFEFQTQVAMITGMEVANASMYDGATGCGEAVLMAHRVTKRRKAVLSGTLHPQYAAVVQNLSDFADYELEVMPPALPGQAEDILAHIHDDISCVVVQTPGFFGELHDLRPIAEAAHAKGALLIAVVPEILSLGAVTPPGEMGADIVVGEGQSIGNGLNFGGPYVGLFATREKYMRQMPGRLCGETVDADGNRGFVLTLSTREQHIRREKATSNICTNSGLCCLAFTIHMSLLGEEGYKRLARINHAAAVKLAERLAKVPGVEILNQAFFNEFTMRLPKPAAEVVDALVDKGVIGGLPASRLLPGVAEVEDLLIVASTEINTEADRAAYEAALKEVL
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: NCAP_I84A2
Sequence: MASQGTKRSYEQMETGGERQNANEIRASVGRMVGGIGRFYIQMCTELKLSDNEGRLIQNSITIERMVLSAFDERRNKYLEEHPSTGRDPKKTGGPIYRRRDGKWVRELVLYDKEELRRIWRQANNGEDATAGLTHLMIWHSNLNDATYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTMVMELIRMIKRGVNDRNFWRGENGRRTRIAYERMCNILKGKFQTAAQRAMMDQVRESRNPGNAEIEDLIFLARSALILRGAVAHKSCLPACVYGLAVASGYDFEREGYSLVGIDPFRLLQNSQVFSIIRPNENPAHKSQLVWMACHSAAFEDLRVSSFIRGTRVLPRGQLSTRGVQIASNENMETMNSSTLELRSRYWAIRTRSGGNTNQQRASAGQVSVQPTFSVQRNLPFERATIMAAFTGNPEGRTSDMRTEIIRMMENSRPEDVSFQGRGVFELSDEKATNPIVPSFDMSNEGSYFFGDNAEEYDN
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: YOCC_SCHPO
Sequence: MHSPIPELPRFERRLTGPRAAPSSPVSTNGSPLNNLVRSRLSDGALNFTGGRIATPLPQPSLKTPESPLSKRNPTIKQNRVRFDLPDDELSRSNVSSPEKTLLTSASTSTFDSLKKELLPELPSLAYSDDDEFPSSPEELNSHVNYPDVRNVYDCHTGLQPLVDHDCIEDRQKTFASKQLPTLPLQKSSKLSNRRPALHSFHSAPANSLYPLPTPTSQLPSNLSSNNLFQSDSLKPSMVSSHTSTKPVLYRGNSEKSCHSCGGSLRAGRIISASGKKLHPQCFKCDTCSQNLEHVGFYYREGKFYCHLDYHEQFSPRCKHCKTPIEDQAVHINNDWFHENHHFCAGCSEVFNVNIPCIYRDDLYWCQTCYDNKYAVKCKKCRKPILGISVKGSDGEYHSQCWTCGACNALLGDEGYFMIENTPICRPCKAISVKFNLD
What are the official names of this protein?
LIM domain-containing protein C4F6.12.
Protein: IORF_CVBLU
Sequence: MASLSGPISPINLEMFKPGVEELNPSKLLLLSNHQEGMLYPTILGSLELLSFKRERSLNLQRDKVCLLHQESQLLKLRGTGTDTTDVPLKQPMATSVNCCHDGIFTILEQDRMPKTSMAPTLTESTGSLVTRLMSIPRLTFSIGTQVAMRLFRLGFRLARYSLRVTILKAQEGLLLIPDLLHAHPVEPLVQDRAVEPILAIEPLPLV
What is the function of this protein?
Structural protein that is not essential for the viral replication either in tissue culture or in its natural host.
What are the official names of this protein?
Protein I, Accessory protein N2, N internal ORF protein, IORF, Protein in nucleocapsid ORF.
What is the protein family that this protein belongs to?
Belongs to the coronavirus I protein family.
What are the subcellular locations of this protein?
Virion.
Protein: HVM41_MOUSE
Sequence: EVKLLESGGGLVQPGGSLKLSCAASGFDFSGYWMSWVRQAPGKGLEWIGEINPDSSTINYTPFLKDKFIISRDNAKNTLFLQMSKVRSEDTALYFCARNWDVGFDYWGQVTTLTVSS
What are the official names of this protein?
Ig heavy chain V region UPC10.
Protein: YML3_ACIFI
Sequence: MPVAIMTATCLGVGFVVLVGVLFKLPVGHGARRVQGNICRYTVTVGKRTGVAYGERLPLLCREFGRQGDFYLPDEDGIAALVVRFDAVPELGSVGGSTTRQDEFGVQNATLAGVVMHQAGTLVGDLHTCAIGRRSSRGTSGAATDRLRG
What are the official names of this protein?
Uncharacterized 15.6 kDa protein in mobL 3'region, ORF 5.