PharMolix/UniProtQA huggingface dataset:
Protein: MTNN_SHIDS
Sequence: MKIGIIGAMEEEVTLLRDKIENRQTISLGGCEIYTGQLNGTEVALLKSGIGKVAAALGATLLLEHCKPDVIINTGSAGGLAPTLKVGDIVVSDEARYHDADVTAFGYEYGQLPGCPAGFKADDKLIAAAEACIAELNLNAVRGLIVSGDAFINGSVGLAKIRHNFPQAIAVEMEATAIAHVCHNFNVPFVVVRAISDVADQQSHLSFDEFLAVAAKQSSLMVESLVQKLAHG
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.  Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: GUAA_GLOC7
Sequence: MATQIPSKPSTSETVPTESLKERINRQMIVILDFGSQYSELIARRIRETNVYSEVLSYRTSAEQLRQLAPKGIILSGGPNSVYDKNAPQCTQEIWDLGIPILGVCYGMQLMVQQLGGKVERAKRAEYGKASLHIDDPTDLLTNVEDNSIAWMSHGDSCIELPDGFKILAHTDNTPCAAIANHEQKLFGVQFHPEVVHSVGGIALIRNFVYHICECEPTWTTEAFVEEAIREIRAKIGDKRVLLALSGGVDSSTLAFLLHRAIGDQLTCMFIDQGFMRKGEPERLMEIFDHQFHIPVVYVNSREQFLEQLKGVTDPEEKRRLIGHEFIKVFEEESNRLGPFDYLAQGTLYPDVIESADSNVDPQTGERVAVKIKSHHNVGGLPKNLRFKLVEPLRKLFKDEVRKVARSIGLPEEIVRRHPFPGPGLAIRIIGEVTSERLKILRDADFVVRDEISKQGMYHDFWQAFAVLLPVRSVGVMGDQRTYAHPVVLRLITSEDGMTADWAKVPYDLLEIISNRIVNEVRGVNRVVYDITSKPPGTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: XB33_ARATH
Sequence: MGNSFGCSASGERLVSAARDGDFVEAKMLLDCNPCLAKYSTFGGLNSPLHFAAAKGHNEIVGLLLENGADVNSRNYCGQTALMQACRYGHWEVVQTLLLFRCNVTRADYLAGRTALHFAAVNGHARCIRLVLADFLPSDKLNSLPETGVVTAKNKSEQSALSKFVNKAADGGITALHMAALNGLFDCVQLLLDLEANVSAVTFHYGTSMDMIGAGSTPLHYAACGGNLKCCQILLARGARKMTLNCNGWLPIDIARMWSRHWLEPLLSPNSDVVIPAFPHSNYLSLPLLSILNIAREFGLQSATIGDEVDICAVCLERTCTVAAEGCEHQLCVRCALYLCSSSNVPSVTVGPPGSIPCPLCRHGITAFKRLPSSLTREMKLPMSLGFCAPCMLHTGDTTDQSSPTCPPTEQRSSKTRAASVSSDIFCPVTCSPFPSVNIPMCTCNEGTCPNFETHGTERHSEEHVESSPSRTTTEQEKIEEGQRLGKTTTCSSMFWGRRSCSRENQCNSEINA
What is the function of this protein?
Possesses E3 ubiquitin-protein ligase activity when associated with the E2 enzyme UBC8 in vitro.
What are the official names of this protein?
E3 ubiquitin-protein ligase XBAT33, Ankyrin repeat domain and RING finger-containing protein XBAT33, Protein XB3 homolog 3, RING-type E3 ubiquitin transferase XBAT33.
Protein: GGAP_MEISD
Sequence: MSSLTPELRQSILEHLGFLYGERAPAVLGRLEEICSGFPAQRREGGWSEKDALLITYGDQIHAEGEPPLQTLYDFLYERLRGVFSGVHLLPFYPSTSDDGFSVVDFQRVDPELGTWTDIRIIAQDFRLMADLVCNHVSASSPWFQGFLQDDPQYQGFFITVDPGTDLSTVFRPRALPLLTPFQTPSGEKLVWTTFSPDQTDLNYANPEVLLEVIEALLCYVRNGAGLIRLDAVGFIWKEIGTSCMHLEGAHRIVKLMRLVLDAVAPHVLLVSETNAPHRENISYFGNGHDEAQLVYQFPLPPLVMHTFRTGDASKLAGWAAGLTLPSERTTFFNFLASHDGIGVVPAGGILQPEEIAALVRQALEHGGRVNHKDTPDGPVPYELCLTLFDALSNPNSDEAEDLKIARFLAANVILLSLQGIPGVYIHSLFGSPSDHAGFEESGIPRRLNRHKFTKAELEERLADPASRAAKILAAYSHLLRVRSMHPAFHPNAPQRILPSTEVLRIVRGEGDQAVGCYINVTDRPQVVSRIGKNLITGQWFTGVLKPYQAAWIID
What is the function of this protein?
Catalyzes the reversible phosphorolysis of glucosylglycerate into alpha-D-glucose 1-phosphate (Glc1P) and D-glycerate.  May be a regulator of intracellular levels of glucosylglycerate, a compatible solute that primarily protects organisms facing salt stress and very specific nutritional constraints.  Has a very strict substrate specificity.  Cannot catalyze the phosphorolysis of sucrose or synthesize sucrose from Glc1P and D-fructose.
What are the official names of this protein?
Glucosylglycerate phosphorylase, GGa phosphorylase, GGaP.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. Glucosylglycerate phosphorylase subfamily.
Protein: RL18_OCEIH
Sequence: MITKPDKNVIRKKRHNRVRRTLSGTAERPRLNVYRSNKNIYAQLIDDNAGVTVASASTADKELAIGGGNVESAKQVGAAIAKRAIDKGYKSIVFDRGGYLYHGRIKALAEAAREEGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: TOLB_SYNC1
Sequence: MRRFVTLLIALLCLSATAVQAQVEIRAPGQQTIAVANTQLVPLSGTPLPAIAAELHDVMAADLELSGLFRQLDPAAFLDDARRPGLTSSRVDFNQWALLGAEILIKGGYQLQGERLLVDFRLYDVVHRRLLTGRRYAGLRRDVRTMAHKFADQVLKSVTGREGPFSSRIAYIDNRTGHKELYLMDTDGANALRLTDHRSIVLNPDFSPNGREVIYTSYRRGNPDLYRKQLSTGQEARLAFKKGLNIAARFRPDGREIALTQSATGNPELMLLGTDGSRRRRLTSHWGIDVDPSWSPAGDRLAFVSDRQGNPHIFVMDLLGGQTARLTANGKYNATPAWSPDGKRIAFTRLEKGVFDIYTVRPDGTDERRLTFGPGNKEHPRWSPDSRFLVYSSDQDGRKGIYIMRADGTGIRRISAGGGQCQHPAWSGQR
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MURA_RICTY
Sequence: MQKLIIHGGKPLEGSINISGAKNAVLPIMAASILTNKLHITNVPKLTDVSTMKDLLQNHGACIRIIEHTDALEIIINTTNINKFTADYEIVRKMRASIWVLGPLLTKYGKAKVSLPGGCAIGARQVDLHIAVLKSMGAEIEIEDGYINASSKGRLKGTHFVFDKVSVGATINAILAAVLANGETVLFNCGREPEIVDLCYCLIKMGADILGVGSSTITIKGKDCLNETSYKVLSDRIEAGTYMFAAAITKGDVKICGIDYNIIENIALKLIETGIKVVQINNGVQVTYAGMLNSVDLETNPYPGFATDLQAQFMSLMSLSRGVSMITENIFENRFMHVPELCRMGADIVVRGNKAVVRGVEMLKGAEVMASDLRASVSLILAGLSTNSKTVLHRIYHLDRGFQDLEKKLSNCGADIKRV
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMM_SALG2
Sequence: MNKVVLLCRPGFEKECAAEITDKAGKREIFGFARVKENAGYVIYECYQPEDGEKLISELPFSSLIFARQWFVVGELLQHLPPEDRITPIVGMLQGVVEKGGELRVEVADTNESKELMKFCRKFTVPLRAALRDAGVLTNYETPKRPVVHVFFIAPGCCYTGYSFAHNNSPFYMGIPRLKFPSDAPSRSTLKLEEALHVFIPEDEWDERLANGMYAVDLGACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFRYRPNRNNISWMVCDMVEKPAKVTALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYLQAQLDEHGVNAQIQARQLYHDREEVTVHVRRLWAAVGGSRDER
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSC_DEIDV
Sequence: MTATLQRESVGTGRVVWFTGLSGAGKSTLASALYEELIARGEQVELLDGDAVRENLSKGLGFTKADRDTNVRRIAFVAGLLAKHGVTVLVSAISPYAETRREVLANLPNPTEVFVDAPLAVVTERDVKGLYLKALAGEIPHFTGVSDPYEAPENPDLHLRTDRISVQDGLKQLLDHLGVNA
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Adenylyl-sulfate kinase, APS kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
Protein: BT1A1_HUMAN
Sequence: MAVFPSSGLPRCLLTLILLQLPKLDSAPFDVIGPPEPILAVVGEDAELPCRLSPNASAEHLELRWFRKKVSPAVLVHRDGREQEAEQMPEYRGRATLVQDGIAKGRVALRIRGVRVSDDGEYTCFFREDGSYEEALVHLKVAALGSDPHISMQVQENGEICLECTSVGWYPEPQVQWRTSKGEKFPSTSESRNPDEEGLFTVAASVIIRDTSAKNVSCYIQNLLLGQEKKVEISIPASSLPRLTPWIVAVAVILMVLGLLTIGSIFFTWRLYNERPRERRNEFSSKERLLEELKWKKATLHAVDVTLDPDTAHPHLFLYEDSKSVRLEDSRQKLPEKTERFDSWPCVLGRETFTSGRHYWEVEVGDRTDWAIGVCRENVMKKGFDPMTPENGFWAVELYGNGYWALTPLRTPLPLAGPPRRVGIFLDYESGDISFYNMNDGSDIYTFSNVTFSGPLRPFFCLWSSGKKPLTICPIADGPERVTVIANAQDLSKEIPLSPMGEDSAPRDADTLHSKLIPTQPSQGAP
What is the function of this protein?
May function in the secretion of milk-fat droplets.  May act as a specific membrane-associated receptor for the association of cytoplasmic droplets with the apical plasma membrane (By similarity).  Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion (By similarity).
What are the official names of this protein?
Butyrophilin subfamily 1 member A1, BT.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. BTN/MOG family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Secreted.
Protein: TRPE_MYCTO
Sequence: MHADLAATTSREDFRLLAAEHRVVPVTRKVLADSETPLSAYRKLAANRPGTFLLESAENGRSWSRWSFIGAGAPTALTVREGQAVWLGAVPKDAPTGGDPLRALQVTLELLATADRQSEPGLPPLSGGMVGFFAYDMVRRLERLPERAVDDLCLPDMLLLLATDVAAVDHHEGTITLIANAVNWNGTDERVDWAYDDAVARLDVMTAALGQPLPSTVATFSRPEPRHRAQRTVEEYGAIVEYLVDQIAAGEAFQVVPSQRFEMDTDVDPIDVYRILRVTNPSPYMYLLQVPNSDGAVDFSIVGSSPEALVTVHEGWATTHPIAGTRWRGRTDDEDVLLEKELLADDKERAEHLMLVDLGRNDLGRVCTPGTVRVEDYSHIERYSHVMHLVSTVTGKLGEGRTALDAVTACFPAGTLSGAPKVRAMELIEEVEKTRRGLYGGVVGYLDFAGNADFAIAIRTALMRNGTAYVQAGGGVVADSNGSYEYNEARNKARAVLNAIAAAETLAAPGANRSGC
What is the function of this protein?
Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan.  In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate.  In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia (By similarity).
What are the official names of this protein?
Anthranilate synthase component 1, AS, ASI.
What is the protein family that this protein belongs to?
Belongs to the anthranilate synthase component I family.
Protein: MNMA_ACIB3
Sequence: MQQRVIVGMSGGVDSSVSAALLLQQGYQVEGLFMKNWEEDDGTEYCTAMEDLADAQAVADKIGIKLHTANFAMEYWDRVFEHFLAEYAAGRTPNPDILCNKEIKFRAFLDHAMTLGADFIATGHYARRAETAYNSKGEAYAPLLRGLDNNKDQTYFLHAVHGREINKTLFPVGEIEKPEVRRIAEELDLATAKKKDSTGICFIGERRFNDFLKQYLPAQPGKIVLDNGKEVGEHHGLMYYTLGQRGGIGLGGMKGASEGAWFVLHKDVANNRLVVGQGHDHPLMQSTQLWSEAIDWVAGEQNIPAEGLRCTAKTRYRQPDQACTVFIDENSEHGVRVEFDEPQRAVTPGQSVVFYSDEVCLGGGVIHHTNAPTPNFI
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADH1_GEOTN
Sequence: MSVARIVFPPLSHVGWGALDQLVPEVKRLGAKHILVITDPMLVKIGLVDQVTSPLRQEGYSVHVYTDVVPEPPLETGEKAVAFARDGKFDLVIGVGGGSALDLAKLAAVLAVHDGSVADYLNLTGTRTLEKKGLPKILIPTTSGTGSEVTNISVLSLETTKDVVTHDYLLADVAIVDPQLTVSVPPRVTAATGIDALTHAVEAYVSVNASPTSDGLAVAAIRLISRSLRKAVANGSDKQARIDMANGSYLAGLAFFNAGVAGVHALAYPLGGQFHIAHGESNAVLLPYVMGYIRQSCTKRMADIFNALGGNSSFLSEVEASYRCVEELERFVADVGIPKTLGGFGIPESALESLTKDAVQQKRLLARSPLPLLEADIRAIYEAAFAGTIVEPHKA
What is the function of this protein?
Long-chain alkyl alcohol dehydrogenase that can oxidize a broad range of alkyl alcohols from ethanol to 1-triacontanol (C2 to C30) as well as 1,3-propanediol and acetaldehyde.  The best substrate is ethanol.  Also oxidizes glycerol.
What are the official names of this protein?
Long-chain-alcohol dehydrogenase 1, Alcohol dehydrogenase 1, ADH1, Fatty alcohol oxidoreductase 1, Glycerol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the iron-containing alcohol dehydrogenase family.
Protein: UBIC_HALHL
Sequence: MREHAAWQPQAAAWRPGVAVVPGRPAPAVQRLLTERGSLTARLERLGPVRVHVLREAWQRPAPDEGVALELPVGRHAWLREVVLDCEGGPTIYARSIVPDRLLGPLARLPRLGERPLGRLLFSAADVQRGPLAVARLRGREPLVRWLRGHGLPSPAGGWARRSTLSVAGRRLLVTEVFFPEGVEGER
What is the function of this protein?
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
What are the official names of this protein?
Probable chorismate pyruvate-lyase, CL, CPL.
What is the protein family that this protein belongs to?
Belongs to the UbiC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBL_AETCO
Sequence: MTQSNPNEQNVELNRTSLYWGLLLIFVLAILFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: NHAB_SHEPW
Sequence: MPVTMSQAFLDNFLGNSPKWFKFAILSFLVINPVVFYLNPFVAGWLLVLEFIFTLAMALKCYPLQPGGLLAIEAVIIGMTSPSQVLHEIEANLEVLLLLIFMVAGIYFMKQLLLFAFTKMITKVRSKIAVSIMCCVASAFLSAFLDALTVIAVIIAVAVGFYSIYHKVASGKNFNDSHDHTSDGQSQLCEEELEAFRGFLRNLLMHAGVGTALGGVCTMVGEPQNLIIAAQANWQFAEFALRMSPVTVPVFVAGVLTCFLVEKFRVFDYGKQLPDAVHKILSDYSAHEDAHRTKHDKIKLIIQALVGVWLIIGLAFHLASVGLIGLSVIILTTAFNGVTNEHQLGKAFEEALPFTALLAVFFAIVGVIIDQQLFAPVIQWALSYEGNTQLVIFYIAIGLLSMVSDNVFVGTVYINEVKAALLDGQITRDQFDLLAVAINTGTNLPSVATPNGQAAFLFLLTSAIAPLIRLSYGRMVWMALPYTIVLSIVGILAIQFGALEQMTQYFYDNNMLLHHTLQEVGNSAASAH
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaB, Sodium/proton antiporter NhaB.
What is the protein family that this protein belongs to?
Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AROQ_XANOM
Sequence: MAHLLLLHGPNLNLLGTREPEVYGRTTLAQIDAALVDRAQAAGHALDCLQSNAEHVLVERIHAAREDGTAYILINPAAFTHTSLALRDALLGVGLPFVEIHLSNPHAREPFRHHSYLSDKADGVICGFGADSYRLALEAVIARLECDA
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: PETM_NEOYE
Sequence: MVGEIVESAVLSSVLVLVGLAIGFLLLKVQGE
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 7, Cytochrome b6-f complex subunit PetM, Cytochrome b6-f complex subunit VII.
What is the protein family that this protein belongs to?
Belongs to the PetM family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single- pass membrane protein.
Protein: HSP1_ANTNA
Sequence: MARYRRHSRSRSRSRYRRRRRRRSRHHNRRRTYRRSRRHSRRRRGRRRGYSRRRYSRRGRRRY
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex (By similarity).
What are the official names of this protein?
Sperm protamine P1.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: STTA_ASPTE
Sequence: MDTISDVMKHCVPINYDDYDPLPADHFSTYPVFCSKATAEAIEASAEFTRKWKRACEVDGLHQDKLSFQACTTHLGHYNQWAYPDCVPERVSLNAVLSDCAFFWDGMSPVTGRSANVMITSPVDVSDSISAEKMNELTQDFGIAMLSELQSGRRIEPKFEINKMAVQVIRDFIAVDPFTGIGHLKEWKGHLDAQKKSTHNNMSWEKYVEHRVNESGGNWGISVGCWTNDIRISDEEKESVKYLTQLACAGGILGNDYYSFPKEFDEHHRSGTLDRIQNGVALLMREYGYTEEEAKEIIKKEVIIREKKWMDGFNAWSRQAGPETGEIRRYLVMTMALMSGSMFWMSHAGRYHRTDLATTAEDRATLIGKSRGALRVLEGYPPPKNLEGIVREPLASAVQDDNGHVQHEDAVADSSVRNGVHDAFKKSNPRNGKQNGTEGSKGTFTNGGYVQPAKLQQHCTSINSMAIYTAPFQEAAGDICDAPYGYIDSLPSKKNRNKLLDLLNDWLQVPPSSLKRIKNIVHMLHNSSLMLDDIEDASALRRGQPATHTFYGISQTINSANYIYVHVVDEVTRLYNPECINIFVDELRNLHRGQSLDLYWRHHARCPSMEEYIVMVDNKTGGLFRLMLRLLTAESSISRPFDTALSRLLTLTGRYYQIRDDYLNLASADYESKKGFCEDFDEGKFSLPLIHLLSHTRYPDRITSALFNRKPGTNLPYEMKRYILAEMEEVQTLAYSQDVLKYLHEELMHALDEAENRLGANDGVRMMLLGMGPKLLLC
What is the function of this protein?
Sesterterpenoid synthase; part of the gene cluster that mediates the biosynthesis of aspterpenacids (PubMed:28604695, PubMed:34085529).  Performs both prenyl transferase and terpene cyclase activity, converting isopentenyl diphosphate and dimethylallyl diphosphate into geranylfarnesyl diphosphate (GFPP) and then converting GFPP into preaspterpenacid I (PubMed:34085529).  C22-oxidative modification of preaspterpenacid I by the cytochrome P450 monooxygenase sttB then leads to preaspterpenacid II.  It has still to be determined how preaspterpenacid II is further modified to produce aspterpenacids (Probable).
What are the official names of this protein?
Preaspterpenacid I synthase sttA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the FPP/GGPP synthase family.
Protein: CSN11_YEAST
Sequence: MFHGAKGPLLIERIGHLLSINYGEKEERKRWAMQGISYLQEVQCTSTPYLEILVEESGLRPVSLLNSQLVGKPHFSLLGGFDENIARDIISHNFQNAIFQMESEEVPLTKRYQHLEKITQISLLCKNFKGIEEIEYNVKNIIQGRKNFDMLNSMEKDRISHEVVQDDSFSLLRIQMLLCVSYFLQERYFDCCTKFFTMMTSEPLTLKVLSEHLDCMNFISKEEFIMMVNISVLISIPLDNYDDFIYLSDLKQFFQMTPLLVNCLELLINTNFNKFFKIWHGEINKICMESLFLEPSWSSSAAVIMRCKIYFFYLRISKKLQFSYLSSTLGIDLEDIKEELTKLIISGQLNFEIDGDVIHFEDSSILQSIVNEISRNGTMINEVIDKLKNENTDLKDIIQGNPLMYSGGNNTATIINNESSDDMDIDEVNDRSDISDSEGGLFEC
What is the function of this protein?
Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes The CSN complex is involved in the regulation of the mating pheromone response.  PCI8 may also be involved in transcriptional and translational control.
What are the official names of this protein?
Cop9 signalosome complex subunit 11, Proteasome-COP9 signalosome-eIF3 domain protein 8.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: XT1_XENTR
Sequence: GFLGPLLKLAAKGVAKVIPHLIPSRQQ
What is the function of this protein?
Has very weak antimicrobial activity against Gram-positive bacterium S. aureus and Gram-negative bacterium E. coli and stronger activity against yeast C. albicans.  Enhances the antibacterial activity of XT3.  Has hemolytic activity against human red blood cells.
What are the official names of this protein?
Antimicrobial peptide 1, XT-1.
What are the subcellular locations of this protein?
Secreted.
Protein: TRM1_METMP
Sequence: MKIISEGETKLMVPEESTLSKKDTVFYNPVMETNRDISVSVVQSFLDDFKRDEFLMCDPLGGSGARGIRYAKELKFNGDLKVSIGDINPSAVKMIKENLKLNELENVEVFHEDANVLLSKNFKVFNVVDLDPFGSPVPYLDSGIRASLTKGGLLCMTATDTAVLCGAYRKTCIRKYNAVPLKGDKELAVRLMIGYAVKMASKYDIGLKPIFSHVTDHYARTFMVTERGAGKADSAIENLGYIRQDSEQKSFKTFEEGSEKGYAGPFYLGEISDKNIVQNALNTAKTRNYSKRAVNILEMISRESEINQVGCFDIHELCSFIKKLVPPVNDIMENLKENGFKVTRVHYNPYGLKTDAELSDLVVLISEYHSKKY
What is the function of this protein?
Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.
What are the official names of this protein?
tRNA (guanine(26)-N(2))-dimethyltransferase, tRNA 2,2-dimethylguanosine-26 methyltransferase, tRNA(guanine-26,N(2)-N(2)) methyltransferase, tRNA(m(2,2)G26)dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
Protein: YL611_MIMIV
Sequence: MEQTNETVQDVQDVQVAGVNEANQVTQNVEPSLISLEKSIFATHSVGRVGILLIDASNSVTFNKINDKIVFDKMVEIVKNLPESEFRCIFWNSDNNRFIDSKSSKFKNGVQVFPSVFKKETINQIFTIVKSSIDEHCLTWPHLSFNAIPDSWINNTDPINIYFITDGEMGHRNIGVEEMMSLKMNLKNSIQKIFDKFNSIRLNIITLEPIVRDFTQMESLRSAAGCDVYNVIMENQMTRYITKFTSYTPDNTNGFVHISRNIPPPGYVPFGDKYFSEIHKNEFVKYILRLVKSTSNEDDLLKIVQNLSTTVSVLTKDKPPQTIRQTVKIFSDLFQKSTLDITLVNYLLEEAVEKETSGSANIFAAYKTKLKDLYKQADELLQTNVSKAIGVNETFLSVLVGNKIISGHARMIDQDTKINGKMWKNSCIDINGVRLPVLPFDTSNQSHMNEQCLRQWMRLLVTRLYNVNTMDDMAIYSVLMMMVRVVASDIDDNVKQAYRKLATIMLKKKRANSDTTELDRLEDGQLPIPNNGKIESFYSYMTKVSANLNLHVSSMTQWYIICLALNNDKLILRQLIHCKDHIEKDFPGIKPSELFDLVKKQIEPVNFVKIPVEYSLDYQCLVTLEDVSNKGGFKFLPHNSLTGDICRPIYVLSEEGQAGLIADPNTSICPICYAQLTHKDFEKVGPKVQQEELNVFTDSSEYKNLFGLNQSIQTITSSASPVISTFTTTANPSTQGFPGFDGRNVVLNKKGTLVIMKGTVGAGKSSISLLIKQEVENNGGHCFVEGTDKYCKTGLSTVEAIQEIKLSLSKINLITDDKPIVVVIDTCGERNNGDVAFDVKFTGWNKINVFVNHIRSEMNGYLAWTLRNVLRRTKPTDSDNHFLNPESAGLKVCMDVHRNKATALFGKKIPVLFSSTPNSINEAIEKLNEAADAYQAIIDQQKPLTDQVKLVIDKIF
What are the official names of this protein?
Uncharacterized protein L611.
Protein: RR2_HUPLU
Sequence: MEPKYWNINLEEMMEAGVHSGHQARKWNPKMAPYIFAERKGIHIINLTRTARFSSEACDSVANVASEGKQFSMVGTKYQAADLTASAAIKARCHYVNKKWLGGMLTNWSTMEKRLQKLRDLENKEKTGGFDRLPEKEAAISKGQLAKLKKYLGGIEYMASLPDVVTIVDQREESIAIKECITLNIPTICLVDTDCDPDLADIPIPANDDARASIRWISDKLASAICEGRKSYMKD
What are the official names of this protein?
30S ribosomal protein S2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL6_BARBK
Sequence: MSRIGKKPIPVPSGVTASIEGQLIKAKGPKGELSYIVNDEVLVKLEDNIVSVTPRDQSKDARSKWGMSHSMIRNIFCGVKDGFEKKLEISGVGYRAALQGKNIQLSLGFSHDVVYKVPSDVSVAVPKPTEIVVSGIDKQKVGQIAAEIRGYRGPEPYKGKGIKYVDESLVRKEGKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: SBP3_ARATH
Sequence: MEFTAEQLSQYNGTDESKPIYVAIKGRVFDVTTGKSFYGSGGDYSMFAGKDASRALGKMSKNEEDVSPSLEGLTEKEINTLNDWETKFEAKYPVVGRVVS
What are the official names of this protein?
Probable steroid-binding protein 3, AtMP3, Membrane-associated progesterone-binding protein 2, AtMAPR2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b5 family. MAPR subfamily.
What are the subcellular locations of this protein?
Nucleus.