PharMolix/UniProtQA huggingface dataset:
Protein: ILVC_SHIB3
Sequence: MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVGCGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLVVNLTPDKQHSDVVRTVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKLVEEGTDPAYAEKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADWANDDKKLLTWREETGKTAFETAPQYEGKIGEQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFSYACVPLLKPFMAELQPGDLGKAIPEGAVDNAQLRDVNEAIRCHAIEQVGKKLRGYMTDMKRIAVAG
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: HEM3_SACS2
Sequence: MKILIAARGSKLSRVQVDMVGEKLRKIGIEYDVIDIKTKADLFSTEPLSKLGKGVFEKEVNEAVLEGKADVAVHSMKDILSEINPELEIFAVIERDPPYDILIAEKNLHKLDPNTTIGTSSIRRKNFIKYIRPEINTKDIRGNVDTRIRKYLSKEYDGLILAEASIKRLNISISYHRLNVYDFTPEANQGIIVVLGRKKDEKVKEVFKEITHKDTLDEALAERATISVVGGGCHSPIGVLFRKEGKEFYGIASYSDGKKKITVSISKAGDPYTIGSELGLLLKKEMKNEGIIP
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Probable porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: ENV_HV1H2
Sequence: MRVKEKYQHLWRWGWRWGTMLLGMLMICSATEKLWVTVYYGVPVWKEATTTLFCASDAKAYDTEVHNVWATHACVPTDPNPQEVVLVNVTENFNMWKNDMVEQMHEDIISLWDQSLKPCVKLTPLCVSLKCTDLKNDTNTNSSSGRMIMEKGEIKNCSFNISTSIRGKVQKEYAFFYKLDIIPIDNDTTSYKLTSCNTSVITQACPKVSFEPIPIHYCAPAGFAILKCNNKTFNGTGPCTNVSTVQCTHGIRPVVSTQLLLNGSLAEEEVVIRSVNFTDNAKTIIVQLNTSVEINCTRPNNNTRKRIRIQRGPGRAFVTIGKIGNMRQAHCNISRAKWNNTLKQIASKLREQFGNNKTIIFKQSSGGDPEIVTHSFNCGGEFFYCNSTQLFNSTWFNSTWSTEGSNNTEGSDTITLPCRIKQIINMWQKVGKAMYAPPISGQIRCSSNITGLLLTRDGGNSNNESEIFRPGGGDMRDNWRSELYKYKVVKIEPLGVAPTKAKRRVVQREKRAVGIGALFLGFLGAAGSTMGAASMTLTVQARQLLSGIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQARILAVERYLKDQQLLGIWGCSGKLICTTAVPWNASWSNKSLEQIWNHTTWMEWDREINNYTSLIHSLIEESQNQQEKNEQELLELDKWASLWNWFNITNWLWYIKLFIMIVGGLVGLRIVFAVLSIVNRVRQGYSPLSFQTHLPTPRGPDRPEGIEEEGGERDRDRSIRLVNGSLALIWDDLRSLCLFSYHRLRDLLLIVTRIVELLGRRGWEALKYWWNLLQYWSQELKNSAVSLLNATAIAVAEGTDRVIEVVQGACRAIRHIPRRIRQGLERILL
What is the function of this protein?
Acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During fusion of viral and target intracellular membranes, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Complete fusion occurs in host cell endosomes and is dynamin-dependent, however some lipid transfer might occur at the plasma membrane.  The virus undergoes clathrin-dependent internalization long before endosomal fusion, thus minimizing the surface exposure of conserved viral epitopes during fusion and reducing the efficacy of inhibitors targeting these epitopes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm.
What are the official names of this protein?
Envelope glycoprotein gp160, Env polyprotein.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 env protein family.
What are the subcellular locations of this protein?
[Surface protein gp120]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM. It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag. SUBCELLULAR LOCATION: [Transmembrane protein gp41]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag.
Protein: NUDC_PSEA7
Sequence: MAGEFRWQAGRPDTAQAGGWALAHCQQRFLQDDNGLLFPREWLKRQDLPLLAEHGVGHWQGEPVYLLELDEPLELPGMAWTPLRQFMLHGDFDQFCMLGYASQIGIWARHNRFCGNCGTRMQALGHERVMQCPQCNLHQYPRLSPSMIVLVTRGDEVLLARSPRFVPGVYSTLAGFVEAGESVEQCVVREVREEVGVEVANLEYIGSQNWPFPHSLMLGFHAEYVSGEIVPQEDEIEDAQWFSLDALPPLPAQRSIARHLIDLYLARRSGAAEPVLPG
What is the function of this protein?
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.  The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing.  Has preference for mRNAs with a 5'-end purine.  Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.
What are the official names of this protein?
NAD-capped RNA hydrolase NudC, DeNADding enzyme NudC, NADH pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudC subfamily.
Protein: MAIA_GEOSE
Sequence: MAKHFRIGMIVPSSNTTMETEIPAMLQSRMKEIPEETFTFHSSRMRMMHVTKEELKKMDEESDRCAIELSDARCDVLAYACLVAIMCQGPGYHEKSEARLASLTAQNGGAAPVISSAGALIDGIRTLGAKKIALIAPYMKPLTNQVIEYITASGIEVTDSISLEIPDNLEVGRQDPMRLIEIVKNLDVSNADAVVLSACVQMPSLPAIQKVQDQLGLPVLSAATSTVYKILKSLNLKTYVPNAGSLLSGKY
What is the function of this protein?
Catalyzes cis-trans isomerization of the C2-C3 double bond in maleate to yield fumarate.
What are the official names of this protein?
Maleate isomerase, Maleate cis-trans isomerase.
What is the protein family that this protein belongs to?
Belongs to the maleate isomerase family.
Protein: CYSI_STAS1
Sequence: MAETKVNFSDKLDEMERIKAHSDYLRGSIVQGLADRVTGAIAEEDTKLLKFHGSYMQDDRDIRDERRRQKLEPAYSFMIRVRAPGGASTAEQWIAMDDIANTYANGTIKLTTRQAFQFHGILKRNLKQTMKDINQSLLDTLAACGDVNRNVMCNPNPYQSDVHSEINQIASAISRHLSPKTQAYHEIWLDGEKVLDTSDEEPEPIYGKTYLPRKFKIGIAVPPSNDIDVYSQDIGLIAILENEQLVGFNVAVGGGMGMKHGNTATYPQVGRLIGYIPKEEVVDVCEKILTVQRDYGNREERTNARFKYTVDRLGVDWIRNEINNRLGWQLENKRPYHFEHNGDRYGWTEGSGKWHYTLFVQNGRVKDTEDYKLKTALRTIAEVHTGDFRLTPNQNLVIANVAAHKKNEIEKIITDFGITDGQHYTGLRRNSMACVAFPTCGLAMAESERYLPSLITKIEDLLDEAGLKEEEITIRMTGCPNGCARPALAEVAFIGKGPGKYNMYLGGGFIGDRLNKIYKENIGEAEILESLRPILLQYAKERTEGEHFGDFVVRAGIVEEVRDGQTFHS
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: HIS1_NEIG1
Sequence: MQDNALTIALSKGRIFEETLPLLAAAGIAPTEEPEKSRKLIIGTNHENIRLVIVRATDVPTYVRYGAADFGIAGKDVLIEHGGTGLYRPLDLEIAKCRMMVAVRKGFDYEAASQPGCRLKIATKYPEIAASHFAGKGVHVDIIKLYGSMELAPLVGLSDAIVDLVSTGNTLKANGLEAVEHIVDISSYLVVNKAALKTKYALLEPIIQSFGGAVKAKWAFI
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR7_EPIVI
Sequence: MSRRGTAEEKTAKPDPIYWNRLVNMLVNRILKHGKKSLAYQIIYRALKKIQQKTEKNPLYVLRQAIRGVTPDIAVKARRVGGSTHQVPIEIGSTQGKALAVRWLLVASKKRPGQNMAFKLSSELVDAAKGSGDAIRKKEETHKMAEASRAFAHLR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, plastid.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid.
Protein: Y091A_ABVP
Sequence: MALVEAVEPIIYGNTKTGISFDSITGAIIAGVVVGLAKTAFLGKFPDYVEVLIGVGLLFMYGQYDLLRGIGFVLTADGIYGLIKNYISTSS
What are the official names of this protein?
Putative transmembrane protein ORF91a.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: URED_FLAJ1
Sequence: MINKLNIVSGFKEGRSYLKDAFFTRPFRIADIKEDKTDPSLYLMLMSSSPGILDNDHYDINIQIESESRLMLESQSYQRLFNMQNGAVQQMNVSLADKSTFSYVQHPIVPHEQSIFKAYNVFNLTDNCSLTVGEIITCGRKHSGEVFLFSKFQNLTEVFHNGKLVVKDNVLLQPLLADVQTLGQMEGFTHQATLMYINTGIEDVESCIELAYAELQSEENIAFGVSKPFANGMIVRVLGNGGEQLYNAFRKIQRKLWIAEEKLNIKSQVTDLAENYI
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAT_TRVCA
Sequence: MAMYDDEFDTKASDLTFSPWVEVENWKDVTTRLRAIKFALQADRDKIPGVLSDLKTNCPYSAFKRFPDKSLYSVLSKEAVIAVAQIQSASGFKRRADEKNAVSGLVSVTPTQISQSASSSAATPVGLATVKPPRESDSAFQEDTFSYAKFDDASTAFHKALAYLEGLSLRPTYRRKFEKDMNVKWGGSGSAPSGAPAGGSSGSAPPTSGSSGSGAAPTPPPNP
What are the official names of this protein?
Coat protein, Capsid protein.
What are the subcellular locations of this protein?
Virion.
Protein: RLME_PHOPR
Sequence: MSRNKQSASSGRWLKEHFDDKYVQEAQKRGYRSRAIFKIEEIQKKDKLLKPGMTVVDLGAAPGGWSQYAAEVVGDEGQVIACDILSMDSLPGVSFLQGDFREEAVLSALLERIQPDMVDVVLSDMAPNMSGNLASDQPRAMYLVELALEMCKQVLAPNGSFAVKVFQGEGFDQYLAEIRNMFKVVKIRKPDSSRDRSREVYIVATGYKL
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: U15_DORVU
Sequence: MSKLLVLFVVSAMALLQFSMVEATPQKFHVNGRYGK
What is the function of this protein?
Probable toxin.  Does not show activity on the ACP receptor (ACPR) from the mosquito A. aegypti, on receptors of the closely related neuropeptides adipokinetic hormone and corazonin.  In vivo, does not reveal any observable effects when injected into crickets (A. domesticus).  Does not induce increase in intracellular calcium in mouse DRG neurons, suggesting that it does not induce pain.
What are the official names of this protein?
U-limacoditoxin(1)-Dv5, U-LCTX(1)-Dv5, Vulnericin.
What is the protein family that this protein belongs to?
Belongs to the limacoditoxin-1 (ACP-like) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RUTD_PSE14
Sequence: MFHEIHRCQHADAPLLVLSSGLGGSSRYWADDLAALTRDHDVLVYDHAGTGRSPADLPADYSIRHMAMELLTLLDSLGIQRCHFMGHALGGLVGLEIALLRPELLQSQVLINAWSSPNPHSARCFSVRKKLLLNSGPDAYVQAQALFLYPADWIAANGARLADDEAHALAHFPGTDNLLRRIHALQTFDVEASLARIQTPTLLIANRDDMLVPWQQSQHLAEALPNARLVLLEYGGHASNITDPLPFQRTLLDFLNAQT
What is the function of this protein?
Involved in pyrimidine catabolism.  May facilitate the hydrolysis of carbamate, a reaction that can also occur spontaneously.
What are the official names of this protein?
Putative carbamate hydrolase RutD, Aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Hydrolase RutD family.
Protein: DER_NOSS1
Sequence: MGLPIVAIIGRPNVGKSTLVNRLAGEQTAIVHDEPGVTRDRTYLPAYWSDREFQVVDTGGLVFNDDTEFLPLIRQQALAALHEASAAIFVVNGQTGPNSADEEIAEWLRQQPVPVFLAVNKCESPDQGSIQASEFWELGLGEPYPISAIHGNGTGELLDELIKHLPPVTELEENNEIKIAIIGRPNVGKSSLLNAFAGEERVIVSPISGTTRDAIDTFIERDGQNYRLIDTAGIRKKKSIDYGTEFFSINRAFKAIRRADVVLLVIDALDGVTEQDQKLAGRILDEGKACVVVVNKWDAVEKDSYTIYDYEKNLEARLHFTEWADTIYVSAVTGQRVEKILELVTKANEEHKRRVSTSVINEVLEDAVRWHSPPTSRGGRQGRIYYGTQVSTQPPTIALFVNEAKRFNDNYRRYIERQFRQQLGFKGTPIRLLWRSKKVRDVESGSANRATRV
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: IF2_ECO5E
Sequence: MTDVTIKTLAAERQTSVERLVQQFADAGIRKSADDSVSAQEKQTLIDHLNQKNSGPDKLTLQRKTRSTLNIPGTGGKSKSVQIEVRKKRTFVKRDPQEAERLAAEEQAQREAEEQARREAEESAKREAQQKAEREAAEQAKREAAEQAKREAAEKDKVSNQQDDMTKNAQAEKARREQEAAELKRKAEEEARRKLEEEARRVAEEARRMAEENKWTDNAEPTEDSSDYHVTTSQHARQAEDESDREVEGGRGRGRNAKAARPKKGNKHAESKADREEARAAVRGGKGGKRKGSSLQQGFQKPAQAVNRDVVIGETITVGELANKMAVKGSQVIKAMMKLGAMATINQVIDQETAQLVAEEMGHKVILRRENELEEAVMSDRDTGAAAEPRAPVVTIMGHVDHGKTSLLDYIRSTKVASGEAGGITQHIGAYHVETENGMITFLDTPGHAAFTSMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAAQVPVVVAVNKIDKPEADPDRVKNELSQYGILPEEWGGESQFVHVSAKAGTGIDELLDAILLQAEVLELKAVRKGMASGAVIESFLDKGRGPVATVLVREGTLHKGDIVLCGFEYGRVRAMRNELGQEVLEAGPSIPVEILGLSGVPAAGDEVTVVRDEKKAREVALYRQGKFREVKLARQQKSKLENMFANMTEGEVHEVNIVLKADVQGSVEAISDSLLKLSTDEVKVKIIGSGVGGITETDATLAAASNAILVGFNVRADASARKVIEAESLDLRYYSVIYNLIDEVKAAMSGMLSPELKQQIIGLAEVRDVFKSPKFGAIAGCMVTEGVVKRHNPIRVLRDNVVIYEGELESLRRFKDDVNEVRNGMECGIGVKNYNDVRTGDVIEVFEIIEIQRTIA
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KGUA_SHESR
Sequence: MTARGNLFIVSAPSGAGKSSLISALLKDKPADMQVSVSHTTRAPRPGEVNGQHYHFVNVEEFKALIEQNAFFEWAEVFGNYYGTSRHVIEHTLTQGIDVFLDIDWQGAQQVKAVMPEAIGVFILPPSRDELERRLTGRGQDSQEVIASRMAQAVSEMSHYKEYDFIIVNDDFDTALADLRAIIRSQRLTGASQIHAQNDMLNDLLAG
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSD_COXBN
Sequence: MTKLHKYLPQRTLSKIVGWLATREWGLLTQWAIRLFIRHYGINMQEAQYPDIGHYPSFNAFFTRYLKRELRPVVEEPLAIASPVDGIISEMGQIKGENLIQAKNHHYTITALLGEDPSRASQFLDGDFFTAYLAPKNYHRIHMPLDGRLIEMIHIPGKLFSVNPASVQTVPRLFARNERAVCLFETENGLMAVILVGAMLVGSINTVWHGTVVPTAEGIAVHNYREKNIKFKRGEEIGHFKMGSTVILLFPKNTIQWNPNCQPKGTICYGENIGTVSLIEVA
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TPO5_YEAST
Sequence: MPEYTLLADNIRENIVHFDPNGLFDNLHTIVHEDDSQENEEAEHFNYDQVLDKSLLSRGSIVGLGLGLMSPVLGMCTSMAIGLINGGPLTIMLGFLISGVCIWFSSLSLGEIVSKFPMELHVGSAMLAPEKLKLVCSWYTGWLMLIGNWTMSTSITFAGAQLTISLILMTNSNLISEAHLIFYTVIVFYLVVTVVGLVNLKFARFIETINKVCVYWIIYAIIFIDILLLVFHKGKFRSLKYALFHFDNNLSGYKSAFLSFIIGFQQSNFTLQGFSMLPALADEVKVPEKDIPRGMSNAVLLSAFSGVIFLIPIMLILPDNDLLFTNHKVLPIVNIFTKSTDSVVLSFFLVLLILGNLLFSGIGSITTSSRAVYSFSRDQAIPYYDKWTYVEPDSQSKVPKNSVVLSMIISYFLGLLALISTAAFNAFIGAAVLCLCSATFIPLVLVLFTRRRAIRSAPVKIRYKFGWFINIVSIVWLLLSMVSVCLPTQVPVTFKTMNYALMVYVFCILVITGLYFKWGKYNFRLPLADDIKAPIPSDAEETVFELEDSNVEHTLNSGTTVKESVENNSEEGFIKVHPKSSTENPFEENEENVITDYGDEHHTAEQEFDLADDRRYDI
What is the function of this protein?
Required for polyamine transport.  Transports putrescine effectively and spermidine less effectively.
What are the official names of this protein?
Polyamine transporter TPO5.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily.
Protein: BAMA_SALTI
Sequence: MAMKKLLIASLLFSSATVYGAEGFVVKDIHFEGLQRVAVGAALLSMPVRTGDTVNDEDISNTIRALFATGNFEDVRVLRDGNTLLVQVKERPTIASITFSGNKSVKDDMLKQNLEASGVRVGESLDRTTLSDIEKGLEDFYYSVGKYSASVKAVVTPLPRNRVDLKLVFQEGVSAKIQQINIVGNHAFSTEELISHFQLRDEVPWWNVVGDRKYQKQKLAGDLETLRSYYLDRGYARFNIDSTQVSLTPDKKGIYITVNITEGDQYKLSGVQVSGNLAGHSAEIEKLTKIEPGELYNGTKVTKMEDDIKKLLGRYGYAYPRVQSQPEINDADKTVKLRVNVDAGNRFYVRKIRFEGNDTSKDSVLRREMRQMEGAWLGSDLVDQGKERLNRLGFFETVDTDTQRVPGSPDQVDVVYKVKERNTGSFNFGIGYGTESGVSFQAGVQQDNWLGTGYSVGINGTKNDYQTYSELSVTNPYFTVDGVSLGGRIFYNDFEADDADLSDYTNKSYGTDVTLGFPINEYNTLRAGLGYVHNKLSNMQPQIAMDRYLESMGDPDASDFAADDFTFNYGWTYNKLDRGYFPTDGSRVNLTGKVTIPGSDNEYYKVSLDTATYVPIDNDHKWVVLGRTRWGYGDGLGGKEMPFYENFYAGGSSTVRGFQSNTIGPKAVYKNGAHTSWDDDDDYEDCTQESGCKSDDAVGGNAMAVASLEFITPTPFISEKYANSVRTSFFWDMGTVWDTNWDPSSAPSDVPDYSDPGNIRMSAGIALQWMSPLGPLVFSYAQPFKKYDGDKAEQFQFNIGKTW
What is the function of this protein?
Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.  Constitutes, with BamD, the core component of the assembly machinery.
What are the official names of this protein?
Outer membrane protein assembly factor BamA.
What is the protein family that this protein belongs to?
Belongs to the BamA family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: RNAS9_PANTR
Sequence: MMRTLITTHPLPLLLLPQQLLQPVQFQEVDTDFDFPEEDKKEDFEEYLEQFFSTGPTRPPTKEKVKRRVLIESGMPLNHIEYCTHEIMGKNVYYKHRCVAERYFLLMQYDELQKICYNRFVPCKNGIRKCNRSKGLVEGVYCNLTEAFEIPACKYESLYRKGYVLITCSWQNEMQKRIPHTINDLVEPPEHRSFLSEDGVFVIPP
What is the function of this protein?
Does not exhibit any ribonuclease activity.
What are the official names of this protein?
Inactive ribonuclease-like protein 9.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: ACH1_YEAST
Sequence: MTISNLLKQRVRYAPYLKKVKEAHELIPLFKNGQYLGWSGFTGVGTPKAVPEALIDHVEKNNLQGKLRFNLFVGASAGPEENRWAEHDMIIKRAPHQVGKPIAKAINQGRIEFFDKHLSMFPQDLTYGFYTRERKDNKILDYTIIEATAIKEDGSIVPGPSVGGSPEFITVSDKVIIEVNTATPSFEGIHDIDMPVNPPFRKPYPYLKVDDKCGVDSIPVDPEKVVAIVESTMRDQVPPNTPSDDMSRAIAGHLVEFFRNEVKHGRLPENLLPLQSGIGNIANAVIEGLAGAQFKHLTVWTEVLQDSFLDLFENGSLDYATATSVRLTEKGFDRAFANWENFKHRLCLRSQVVSNNPEMIRRLGVIAMNTPVEVDIYAHANSTNVNGSRMLNGLGGSADFLRNAKLSIMHAPSARPTKVDPTGISTIVPMASHVDQTEHDLDILVTDQGLADLRGLSPKERAREIINKCAHPDYQALLTDYLDRAEHYAKKHNCLHEPHMLKNAFKFHTNLAEKGTMKVDSWEPVD
What is the function of this protein?
Presumably involved in regulating the intracellular acetyl-CoA pool for fatty acid and cholesterol synthesis and fatty acid oxidation.  It may be involved in overall regulation of acetylation during melatonin synthesis.
What are the official names of this protein?
Acetyl-CoA hydrolase, Acetyl-CoA deacylase, Acetyl-CoA acylase.
What is the protein family that this protein belongs to?
Belongs to the acetyl-CoA hydrolase/transferase family.
Protein: KAIB_THEVL
Sequence: MAPLRKTYVLKLYVAGNTPNSVRALKTLNNILEKEFKGVYALKVIDVLKNPQLAEEDKILATPTLAKVLPPPVRRIIGDLSNREKVLIGLDLLYEEIGDQAEDDLGLE
What is the function of this protein?
A metamorphic protein which reversibly switches between an inactive tetrameric fold and a rare, thioredoxin-like monomeric fold (KaiB(fs)).  KaiB(fs) binds phospho-KaiC, KaiA and CikA.  KaiA and CikA compete for binding to KaiB(fs), and KaiB(fs) and SasA compete for binding to KaiC, thus the clock oscillator and output signal pathway are tightly coupled.
What are the official names of this protein?
Circadian clock oscillator protein KaiB.
What is the protein family that this protein belongs to?
Belongs to the KaiB family.
Protein: IOVO_GYPCO
Sequence: IAIVDCSDYPKPVCSLEYMPLCGSDSKTYSNKCDFCNAVVDSNGTLTLSHFGKC
What are the official names of this protein?
Ovomucoid.
What are the subcellular locations of this protein?
Secreted.
Protein: RL11_ACIB5
Sequence: MAKKIDGYIKLQVPAGKANPSPPIGPALGQRGVNIMAFCKEFNAATQKVEPGLPIPVVITVYNDKSFTFIMKTPPASILLKKAAGIQKGSSVPNKTKVGKLTRAQLEEIATTKEPDLTGADLDARVRTIAGSARSMGLEVEL
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: PP4R3_KLULA
Sequence: MSESNNMHVSGDGAKQSVYTEKKRVKVYVLENNEWKDTGTGFCQGTVEERTIDDTQTAEKMAYLLVVDEDSDDQVLLKSRLEQNIEYQRQEETLIVWKDLNGQDIALSFEESIGCDSLCEYICFVQKNIESRISLVAVRSTDDGIGSVHEIITGPVNLPSNVPNQTEESLLEALKILNENTSFDYLRNETIQFVINDHYLATLIRSFYQSEESKLYRNLLLLSNIVKTLILFNSKEILEEMINDENFLCVCGILEYDTEFPNSKLNHRQYLKDKEPNFKEMIPISDPTIKLMITQNFRLQFLKDVVLVRFLDDQSFTFISDLMLSYQNSIIDFLQEDSNNFINQVISMYKVEEDSTVTPDKRRDGIKLLHECIQLSQNLNSIEKTLFYKFLIKKGLFQVIQFAFNMETNNDIRILATDIVVGLIEHDIQLIQSVQSDEVTLLNDENSDIDSTDMSLLLILTKILLTDKSPGLKEQSFQALVSLLDPEDYIVDDYQNHDDNIDTRIDNMLQIQNGKNHDGLDGERNHEKFQLAEYLQCFYRQVAPSLFHCFIDGSVNLYECDQQLLIKLVKLLNLMIQGHEASISRRFILENGILIRLISLASSDYILQLRLAAVRCFKNIVFLNDDFYLRYLIGKNLFDPIFEVFKENLNEDNMANSTILDFLKSLNTQLKVVEQEDIPLSGSKSSRNFMLLNKYICGRYGDILLKADYVSFTREMMAIYHEETQKLASLSTTETSFDENDNTTLEVEV
What is the function of this protein?
Core regulatory subunit of the histone H2A phosphatase complex, which dephosphorylates H2AS128ph (gamma-H2A) that has been displaced from sites of DNA lesions in the double-stranded DNA break repair process.  Dephosphorylation is necessary for efficient recovery from the DNA damage checkpoint (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase 4 regulatory subunit 3, PP4R3.
What are the subcellular locations of this protein?
Nucleus.
Protein: BRK5_PITHY
Sequence: RPPGFTPFR
What is the function of this protein?
[Thr6]-bradykinin: inhibits ACE with a Ki of 1. 6 uM, and targets B2 bradykinin receptor (BDKRB2).  Provokes contraction of smooth muscle preparation (ileum).  In vivo, induces an early hyperalgesic effects in living rats after intraplantar injection (By similarity).
What are the official names of this protein?
[Thr6]-bradykinin.
What is the protein family that this protein belongs to?
Belongs to the bradykinin-related peptide family.
What are the subcellular locations of this protein?
Secreted.