PharMolix/UniProtQA huggingface dataset:
Protein: HELS_ARCFU
Sequence: MKVEELAESISSYAVGILKEEGIEELFPPQAEAVEKVFSGKNLLLAMPTAAGKTLLAEMAMVREAIKGGKSLYVVPLRALAGEKYESFKKWEKIGLRIGISTGDYESRDEHLGDCDIIVTTSEKADSLIRNRASWIKAVSCLVVDEIHLLDSEKRGATLEILVTKMRRMNKALRVIGLSATAPNVTEIAEWLDADYYVSDWRPVPLVEGVLCEGTLELFDGAFSTSRRVKFEELVEECVAENGGVLVFESTRRGAEKTAVKLSAITAKYVENEGLEKAILEENEGEMSRKLAECVRKGAAFHHAGLLNGQRRVVEDAFRRGNIKVVVATPTLAAGVNLPARRVIVRSLYRFDGYSKRIKVSEYKQMAGRAGRPGMDERGEAIIIVGKRDREIAVKRYIFGEPERITSKLGVETHLRFHSLSIICDGYAKTLEELEDFFADTFFFKQNEISLSYELERVVRQLENWGMVVEDHHLAPTKLGSLVSRLYIDPLTGFIFHDVLSRMELSDIGALHLICRTPDMERLTVRKTDSWVEEEAFRLRKELSYYPSDFSVEYDWFLSEVKTALCLKDWIEEKDEDEICAKYGIAPGDLRRIVETAEWLSNAMNRIAEEVGNTSVSGLTERIKHGVKEELLELVRIRHIGRVRARKLYNAGIRNAEDIVRHREKVASLIGRGIAERVVEGISVKSLNPES
What is the function of this protein?
DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
What are the official names of this protein?
ATP-dependent DNA helicase Hel308.
What is the protein family that this protein belongs to?
Belongs to the helicase family. Hel308 subfamily.
Protein: ATP6_STRPI
Sequence: MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTLKPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTIDGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEEFTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQAYVFTLLTSVYLGNKINIEEE
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LEU3_STAAR
Sequence: MTYNIVALPGDGIGPEILNGSLSLLEIISNKYNFNYQIEHHEFGGASIDTFGEPLTEKTLNACKRADAILLGAIGGPKWTDPNNRPEQGLLKLRKSLNLFANIRPTTVVKGASSLSPLKAERVEGTDLVIVRELTSGIYFGEPRYFNNHEALDSLTYTREEIERIVHVAFKLAASRRGKLTSVDKENVLASSKLWRKVVNEVSQLYPEVTVNHLLVDACSMHLITNPKQFDVIVYENLFGDILSDEASVIPGSLGLSPSASFSNDGPRLYEPIHGSAPDIAGKNVANPFGMILSLAMCLRESLNQPDAADELEQHIYNMIEHGQTTADLGGKLNTTDIFEILSQKLNH
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVC_MYCSJ
Sequence: MRVMGVDPGLTRCGLSVIESGQGRKVIALDVDVVRTPADEQLHRRLLIISDTVEHWMDTHRPDVIAIERVFANHNANTAMGTAQAGGVIALAAAKRDIDVHFHTPSEVKAAVTGNGRADKAQVTEMVTRILALQAKPTPADAADALALAICHCWRAPMIARMAAAEAMAAEARRKYQAKLKAARA
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: DPOL_HBVH1
Sequence: MPLSYQHFRRLLLLDNEAGPLEEELPRLADEDLNHRVAEDLNLQLPNVSIPWTHKVGNFTGLYSSTIPVFNPDWLTPSFPDIHLHQDLIQKCEQFVGPLTTNERRRLKLIMPARFYPKVTKYFPLDKGIKPYYPENVVNHYFKTRHYLHTLWKAGILYKRESTHSASFCGSPYSWEQELQHGSTSLNGEKGHGTEPFCAQSSGILSRPPVGSTIQSKFQQSRLGLQHKQGQLANGKQGRSGRLRSRVHTPTRWPSGVEPSGTGHSDNLATRSTSCFHQSEVRKKANPSLSTSKGHTSTGHAVELNTVPPSTVGSESKGSVFSCWWLQFRNTEPCSDYCLSHIINLLEDWGPCYEHGEHHIRTPKTPSRVTGGVFLVDKNPHNTTESRLVVDFSQFSRGTTRVSWPKFAVPNLQSLTNLLSSNLSWLSLDVSAAFYHLPLHPAAMPHLLVGSSGLSRYVARVSSTSRIYNHQHGTLQNLHHSCSRNLYVSLLLLYQTFGRKLHLYSHPIILGFRKIPMGVGLSPFLLAQFTSAICSVVRRAFPHCLAFSYMDDLVLGAKSVQHLESLYTAVTNFLLSVGIHLNTAKTKWWGYSLHFMGYIIGSWGTLPQEHIVHKIKDCFRKLPVNRPIDWKVCQRIVGLLGFAAPFTQCGYPALMPLYACITAKQAFVFSPTYKAFLCKQYMNLYPVARQRPGLCQVFADATPTGWGLAIGHQRMRGTFVAPLPIHTAELLAACFARSRSGADIIGTDNSVVLSRKYTSFPWLLGCAANWILRGTSFVYVPSALNPADDPSRGRLGLCRPLLRLPFRPTTGRTSLYADSPPVPSHLPARVHFASPLHVAWRPP
What is the function of this protein?
Multifunctional enzyme that converts the viral RNA genome into dsDNA in viral cytoplasmic capsids.  This enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes in a partially processive 3'- to 5'-endonucleasic mode.  Neo-synthesized pregenomic RNA (pgRNA) are encapsidated together with the P protein, and reverse-transcribed inside the nucleocapsid.  Initiation of reverse-transcription occurs first by binding the epsilon loop on the pgRNA genome, and is initiated by protein priming, thereby the 5'-end of (-)DNA is covalently linked to P protein.  Partial (+)DNA is synthesized from the (-)DNA template and generates the relaxed circular DNA (RC-DNA) genome.  After budding and infection, the RC-DNA migrates in the nucleus, and is converted into a plasmid-like covalently closed circular DNA (cccDNA).  The activity of P protein does not seem to be necessary for cccDNA generation, and is presumably released from (+)DNA by host nuclear DNA repair machinery.
What are the official names of this protein?
Protein P.
What is the protein family that this protein belongs to?
Belongs to the hepadnaviridae P protein family.
Protein: CBPM_ECO7I
Sequence: MANVTVTFTITEFCLHTGISEEELNEIVGLGVVEPREIQETTWVFDDHAAIVVQRAVRLRHELALDWPGIAVALTLMDDIAHLKQENRLLRQRLSRFVAHP
What is the function of this protein?
Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA.  Together with CbpA, modulates the activity of the DnaK chaperone system.  Does not inhibit the co-chaperone activity of DnaJ.
What are the official names of this protein?
Chaperone modulatory protein CbpM.
What is the protein family that this protein belongs to?
Belongs to the CbpM family.
Protein: PSB1_STRAW
Sequence: MAQRDTGGRLGAEFFTPGDSSFTAFLAAHRPALLSTRGLLPDGVRAAPDRVPHGTTVLALAYRDGVLIAGDRRATMGNLIAQRDLEKVHPADDYTAVAFAGTVGLALDMVKLYQVELAHFEKVEGVPMTLRAKATRLAGMIRQNLGQAMQGLAVVPLLVGYDLAARAGEHGRIFSFDVTGGPYEKTDFHAEGSGSPYARGALKKLFHPGMSRREAALAALQALYDAADDDSATGGPDISRRIFPVVSVITEDGFERLPESETEDLSREMVEQRHTRPDGPTAAM
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta 1, 20S proteasome beta subunit 1, Proteasome core protein PrcB 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUC_CAMJD
Sequence: MAKTLYEKVFDAHVVYENENELPILYIDRHLIHEVTSPQAFSGLKMAKRRMARADLTLATIDHDVSTKSVDLNACSDMAKEQITTLMQNTKEFGVRLLGLGDKNQGIVHIVSPELGFTLPGVTLVCGDSHTATHGAFGALAFGIGTSEVEHVMATQTLKQAKLKTMKIECKGQFQKGVYAKDLILYLIAQYGTAKGTGYAIEFCGELIRNLSMEARMTLCNMAIEFGAKVGMIAPDEITFEYIKGKEFAPKGEEFQKYCEYWKSLRSDEGAKYDESITLDVSKIKPQISYGTNPSQVIGIDEKIPKISDFKNQSEQKSLLDALSYVNLEQDQVIEGVKIDIVFIGSCTNGRLEDLKIAADILKGRKIHKNVKALIVPGSMQVRKEAENLGLDKIFIEAGCEWRYAGCSMCLGMNDDKANSGQRVASTSNRNFVGRQGKGSITHLMSPASAAACAIEGVICDNRKYLGV
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: RS20_GLUDA
Sequence: MANTASARKRIRQNERRNARNTARVSRMRTFVKKVEAAIASGNKDEATAALRAAQPEMQRASGKGVIHANTVARKISRLSARIKSIVAA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: H33_PIG
Sequence: MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
What is the function of this protein?
Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes.  Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis.  Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.3.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: Y1903_STRPN
Sequence: MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDHTLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYIDYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFSEAYVNIWYKRYVELKNR
What are the official names of this protein?
UPF0374 protein SP_1903.
What is the protein family that this protein belongs to?
Belongs to the UPF0374 family.
Protein: SIA7B_HUMAN
Sequence: MGLPRGSFFWLLLLLTAACSGLLFALYFSAVQRYPGPAAGARDTTSFEAFFQSKASNSWTGKGQACRHLLHLAIQRHPHFRGLFNLSIPVLLWGDLFTPALWDRLSQHKAPYGWRGLSHQVIASTLSLLNGSESAKLFAPPRDTPPKCIRCAVVGNGGILNGSRQGPNIDAHDYVFRLNGAVIKGFERDVGTKTSFYGFTVNTMKNSLVSYWNLGFTSVPQGQDLQYIFIPSDIRDYVMLRSAILGVPVPEGLDKGDRPHAYFGPEASASKFKLLHPDFISYLTERFLKSKLINTHFGDLYMPSTGALMLLTALHTCDQVSAYGFITSNYWKFSDHYFERKMKPLIFYANHDLSLEAALWRDLHKAGILQLYQR
What is the function of this protein?
Catalyzes the transfer of N-acetylneuraminyl groups onto glycan chains in glycoproteins (PubMed:10742600, PubMed:29251719).  Shows a preference for N-acetylgalactosamine (GalNAc) residues already modified by the addition of galactose or galactose followed by sialic acid in alpha-2,3 linkage (PubMed:10742600).
What are the official names of this protein?
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2, GalNAc alpha-2,6-sialyltransferase II, ST6GalNAc II, ST6GalNAcII, SThM, Sialyltransferase 7B, SIAT7-B.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 29 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: UTP18_HUMAN
Sequence: MPPERRRRMKLDRRTGAKPKRKPGMRPDWKAGAGPGGPPQKPAPSSQRKPPARPSAAAAAIAVAAAEEERRLRQRNRLRLEEDKPAVERCLEELVFGDVENDEDALLRRLRGPRVQEHEDSGDSEVENEAKGNFPPQKKPVWVDEEDEDEEMVDMMNNRFRKDMMKNASESKLSKDNLKKRLKEEFQHAMGGVPAWAETTKRKTSSDDESEEDEDDLLQRTGNFISTSTSLPRGILKMKNCQHANAERPTVARISSVQFHPGAQIVMVAGLDNAVSLFQVDGKTNPKIQSIYLERFPIFKACFSANGEEVLATSTHSKVLYVYDMLAGKLIPVHQVRGLKEKIVRSFEVSPDGSFLLINGIAGYLHLLAMKTKELIGSMKINGRVAASTFSSDSKKVYASSGDGEVYVWDVNSRKCLNRFVDEGSLYGLSIATSRNGQYVACGSNCGVVNIYNQDSCLQETNPKPIKAIMNLVTGVTSLTFNPTTEILAIASEKMKEAVRLVHLPSCTVFSNFPVIKNKNISHVHTMDFSPRSGYFALGNEKGKALMYRLHHYSDF
What is the function of this protein?
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.  Involved in nucleolar processing of pre-18S ribosomal RNA.
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 18 homolog, WD repeat-containing protein 50.
What is the protein family that this protein belongs to?
Belongs to the WD repeat UTP18 family.
Protein: MAB31_CAEEL
Sequence: MNSLEYLIANPHILSDTTLTDALAALASSTNVENQDEEFDMEVNSDDEMKIDLSALINPSVFNALQLPIGTGRFPNPSPPRSSSGTNTPIRKTPGSRPDRGKFTILDNAEVAGPEEVLNVNFDSEILQRIFSDPKLGIQFLARYGLIPNTRVCRVQDCPKDQLMSLIKHANGFVWRCRSCRKRREKRIITKISVYEGTFLFYSRMPLNKFFIFMLNWCENPGLSITEYNRLMGENRLVEETIYNTIGFMRDIIQNWCDTIISSHVPIGGPHRVVEVVETLSTEQLSNKTRNRRTRHYTTRTVFISLADDKIKSVDFPLHNVNDLERALLECVQPGSIIVMRDSFMERFGQQEEISNALFNHYKVKSICDVWPDFNERERNKQYIKTEMNQVPNVNQEPYAYEYFFRRCFADKCFNHLLRVIRLLYQK
What is the function of this protein?
Putative transcription factor (PubMed:32758726).  Acts in a TGF-beta-like pathway during development of male-specific genital sensilla (simple sense organs), known as rays (PubMed:20687916).  Involved in production of reactive oxygen species (ROS), acting downstream of the TGF-beta-like dbl-1 signaling pathway (PubMed:32758726).  Involved in locomotory behavior (PubMed:32758726).
What are the official names of this protein?
Male abnormal protein mab-31.
Protein: FADE5_MYCS2
Sequence: MSHYKSNVRDQVFNLFEVFGVDKVLGADKFSDLDADTAREMLTEIARLAEGPIAESFVEGDRNPPVFDPETHTVTLPEGFKKSMRALFDGGWDKVGLAEHLGGIPMPRALQWALIEHILGANPAAYMYAMGPGMSEIFYNNGTDEQKKWATIAAERGWGATMVLTEPDAGSDVGAGRTKAVQQPDGTWHIEGVKRFITSADSDDLFENIMHLVLARPEGAGPGTKGLSLFFVPKFHFDHETGEIGERNGVFVTNVEHKMGLKVSATCELSLGQHGIPAVGWLVGEVHNGIAQMFDVIEQARMMVGTKAIATLSTGYLNALEYAKERVQGADMTQMTDKTAPRVTITHHPDVRRSLMTQKAYAEGLRAIYLYTATFQDAEVAQAVHGVDGDLAARVNDLLLPIVKGFGSETAYAKLTESLQTLGGSGFLQDYPIEQYIRDSKIDSLYEGTTAIQAQDFFFRKIIRDKGQALAYVAGEIEQFIKNENGNGRLKTERELLATALADVQGMAASLTGYLMAAQEDAASIYKVGLGSVRFLMAVGDLLSGWLLARQAAVAIEKLDAGATGADKSFYEGKIAAASFFAKNMLPLLTSTRQIIENLDNDVMELDEAAF
What is the function of this protein?
Acyl-CoA dehydrogenase that exhibits broad specificity for linear acyl-CoA substrates, with a preference for long-chain substrates.
What are the official names of this protein?
Broad-specificity linear acyl-CoA dehydrogenase FadE5, Long-chain-acyl-CoA dehydrogenase, Medium-chain-acyl-CoA dehydrogenase, Short-chain-acyl-CoA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
Protein: RK33_LEMMI
Sequence: MAKGKDVRVRVILECNSCGRNENGVTKEVPGVSRYVTQKNRHNTPSRLELKKFCRYCNKHTIHVEVKK
What are the official names of this protein?
50S ribosomal protein L33, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CHHB_HOMAM
Sequence: MFACRTLCLVVVMVASLGTSGVGGRSVEGVSRMEKLLSSSISPSSTPLGFLSQDHSVNKRQVFDQACKGVYDRNLFKKLNRVCEDCYNLYRKPFIVTTCRENCYSNRVFRQCLDDLLLSDVIDEYVSNVQMVGK
What is the function of this protein?
Hormone found in the sinus gland of isopods and decapods which controls the blood sugar level.  Has a secretagogue action over the amylase released from the midgut gland.  May act as a stress hormone and may be involved in the control of molting and reproduction.
What are the official names of this protein?
Crustacean hyperglycemic hormones isoform B.
What is the protein family that this protein belongs to?
Belongs to the arthropod CHH/MIH/GIH/VIH hormone family.
What are the subcellular locations of this protein?
Secreted.
Protein: DSBB_NITEU
Sequence: MRIIFLLIALICAGLVSYALYLQLADGLLPCPLCIFQRMAYWLVGITALFAFIHHPQRLGRRIYCGLIILFSLAGAIVAGRQAWLVRFPEAFECGISPEEAFLNELPLARWWPDMFEANGDCTDGTWQFLSLTIPDWSLLIFLAFSLIAGLLWRSRSISSSNLK
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by oxidizing the DsbA protein.
What are the official names of this protein?
Disulfide bond formation protein B, Disulfide oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the DsbB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DPHB_METB6
Sequence: MLTFIGLGLYDKTDVSEKGLAMIRSADYVFLEGYTSRLMGTNITELEAFYKKPVRLLLRADVEQHPDELLDCAARGNTVFLCAGDPMVSTTHADLRIRAAERGIPTAIIHGSSIVSAVCGLSGLQNYRFGKSCSVPFPQGNWAPSSPLDVILENRTNRLHTLVYLDIQDDRYMTVNEGICLLEAMAQKKQVAIPFYVGVARAGSETSLVRAGTAETLRSADFGPPLHILIVPGELHDMEREYLARFAGLC
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine.  The three successive methylation reactions represent the second step of diphthamide biosynthesis.
What are the official names of this protein?
Diphthine synthase, Diphthamide biosynthesis methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the diphthine synthase family.
Protein: GLMU_AGRRK
Sequence: MERTCLAIILAAGDSTRMKSSISKVLHPIAGRPMIAHVMEAIARTDISAAALVVGRNAEEVAAAADIGGIEVEAYLQKERLGTGHAVLAAREAIARGYDDIIVAYGDVPLLTDVPLRAARKGLADGNDIVVIGFHTENPNAYGRLLVKDGELIAIREAKDATDAELAVTWCNSGLMAINGRKALDLLDRIGNSNAKGEYYLTDLVEIARSLGGRAIAVDAPEVEMTGCNNRAELAFIERLWQERRRHELMLSGVTMIAPETVFLAYDTVIGQDALIEPNVVFGPRVVIDSGAVIHAFSHIEGAHVSGTATVGPFARLRPGADLADGSKVGNFCEVKNGKIGKGAKVNHLSYIGDATIGAGSNIGAGTITCNYDGVNKHETHIGANSFIGSNSSLVAPVRIGDNAYVASGSVITEDVPADALAFGRARQEVKLGRAKVIRERALAIKAAKKGSH
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTL_LEPBL
Sequence: MGKIQELSPELINQIAAGEVIESAHSVVKELMENSMDAGATQMDIESKDGGLSLLRITDNGSGIDPEDIEPALKRHATSKIRDYGDLENVLSYGFRGEALASIASVSRLTLESGIKNQKTAWKICSIGGKISEKEEIPGFVGTKILVEELFFNTPVRRKFLKSVRSEDKKIRDRVTTQALARHDVRFRLFQDGKEVFVLPSRENKKDRIVDLFGENFRDHLLEVSLERGGLNATGYISDPDFYKSNRTGQFVFVNGRPVEIKYGSTLLKKAYDELLPPNGHPYCFLFFEIDPSRVDVNVHPAKKEIRFLDEEGFNGFFLTLIQKELRSSTPVSFLELKKRLLRPTPETFKTSSLYQAHSSSRSGESPLLSRELFTEVPRQEGFDLDRMGPGASLSALTDNVVKHSSFVPKKHFGVLFETFILAEAEDGFYIIDQHTAHERIRYEEVLRKLEKKNYGIQPLLTPIRIDVSKQEQEDILNRKKEYEEVGIFLDPLGEDSVVLREIPAYMEPGEEKEIILDFLNRTEGKETTEPELYDLMAKCVACRSAIKKGDHLSDPILAEILNRLSYCENPSRCPHGRPTLVKLSRDDLERMFHRK
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: O1620_CONCL
Sequence: MKLTCVLIVAVLILTACQVIAADGWFGEESSCWWCTGQNKCCEEAQVCQSVNYACPPARR
What is the function of this protein?
Probable neurotoxin.
What are the official names of this protein?
Conotoxin Cal6.20, O1_cal6.20.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CYB_OENBE
Sequence: MATIRNQRFSLLKQPISSILNQHLIDYPTPSNLSYWWGFGSLAGICLVIQIVTGVFLAMHYTPHVDLAFNSVEHIMRDVEGGWLLRYMHANGASMFFIVVYLHTFRGLYYASYSSPREFVWCLGVVIFLLMIVTAFIGYVLPWGQMSFWGATVITSLASAIPVVGDTIVTWLWGGFSVDNATLNRFFSLYHLLPFILVGASLLHLAALHQYGSSNPLGVHSEMDKISFYPYFYVKDLVGWVAFAIFFSIWIFYAPNVLGHPDNYIPANPMSTPPHIVPEWYFLPIYAILRSIPDKAGGVAAIALVFICLLALPFFKDMYVRSSSFRPIYQGIFWLLLADCLLLGWIGCQPVEAPFVTIGQISSIVFFLFFAITPILGRVGRGIPNSYTDETDHT
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SPSA1_ARATH
Sequence: MAGNDWVNSYLEAILDVGQGLDDARSSPSLLLRERGRFTPSRYFVEEVITGYDETDLHRSWVKAVATRSPQERNTRLENMCWRIWNLARQKKQHEEKEAQRLAKRRLEREKGRREATADMSEEFSEGEKGDIISDISTHGESTKPRLPRINSAESMELWASQQKGNKLYLVLISLHGLIRGENMELGRDSDTGGQVKYVVELARALGSMPGVYRVDLLTRQVSSPDVDYSYGEPTEMLTPRDSEDFSDEMGESSGAYIVRIPFGPKDKYIPKELLWPHIPEFVDGAMSHIMQMSNVLGEQVGVGKPIWPSAIHGHYADAGDATALLSGALNVPMLLTGHSLGRDKLEQLLRQGRLSKEEINSTYKIMRRIEGEELSLDVSEMVITSTRQEIDEQWRLYDGFDPILERKLRARIKRNVSCYGRFMPRMVKIPPGMEFNHIVPHGGDMEDTDGNEEHPTSPDPPIWAEIMRFFSNSRKPMILALARPDPKKNITTLVKAFGECRPLRELANLALIMGNRDGIDEMSSTSSSVLLSVLKLIDKYDLYGQVAYPKHHKQSDVPDIYRLAAKSKGVFINPAIIEPFGLTLIEAAAHGLPMVATKNGGPVDIHRVLDNGLLVDPHDQQSISEALLKLVADKHLWAKCRQNGLKNIHQFSWPEHCKTYLSRITSFKPRHPQWQSDDGGDNSEPESPSDSLRDIQDISLNLKFSFDGSGNDNYMNQEGSSMDRKSKIEAAVQNWSKGKDSRKMGSLERSEVNSGKFPAVRRRKFIVVIALDFDGEEDTLEATKRILDAVEKERAEGSVGFILSTSLTISEVQSFLVSGGLNPNDFDAFICNSGSDLHYTSLNNEDGPFVVDFYYHSHIEYRWGGEGLRKTLIRWASSLNEKKADNDEQIVTLAEHLSTDYCYTFTVKKPAAVPPVRELRKLLRIQALRCHVVYSQNGTRINVIPVLASRIQALRYLFVRWGIDMAKMAVFVGESGDTDYEGLLGGLHKSVVLKGVSCSACLHANRSYPLTDVISFESNNVVHASPDSDVRDALKKLELLKD
What is the function of this protein?
Plays a major role in photosynthetic sucrose synthesis by catalyzing the rate-limiting step of sucrose biosynthesis from UDP-glucose and fructose- 6-phosphate.  Involved in the regulation of carbon partitioning in the leaves of plants.  May regulate the synthesis of sucrose and therefore play a major role as a limiting factor in the export of photoassimilates out of the leaf.  Plays a role for sucrose availability that is essential for plant growth and fiber elongation.  Required for nectar secretion.
What are the official names of this protein?
Sucrose-phosphate synthase 1, Sucrose-phosphate synthase 1F, AtSPS1F, Sucrose-phosphate synthase 5.1, AtSPS5.1, UDP-glucose-fructose-phosphate glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family.
Protein: RLMG_PSEAB
Sequence: MPLFATPFAQLDLVRQPEQDGEPLQAFDAADEYLLNQLHERGVTAQCRVLVLNDAFGALAASLAPHVQVTSSGDSHLGFLALRKNLARNGLDLGSVRFVPASETAVGPFDHVLVKVPKTLALLEEQLIRLHGQLAPGAQVVAAGMVKHLPRAAGDLLERYIGPMHASLAVKKARLLIAEAAERPQPRSPYPTRYRLEQPPLTLLNHANVFCREGLDIGTRAFLPHLPRSLGALRAADLGCGNGVLGIAYALLNPQAELTLVDESYMAVQSARENWRAALGERPATFRADDGLAGQAAGSLDLVLCNPPFHQQQVVGDFLAWRMFLQARDALAAGGELWIVGNRHLGYHAKLKRLFRGVEQVAANPKFVILKAGK
What is the function of this protein?
Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase G, 23S rRNA m2G1835 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RlmG.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmG family.
What are the subcellular locations of this protein?
Cytoplasm.