PharMolix/UniProtQA huggingface dataset:
Protein: APM1B_ORYSJ
Sequence: MAASPEQFRGQARLPRCASPLSYDLRLRPDLAACAFSGSAAVAVAVSAPTRFLVLNAAELAVDGSSVRFQDLVPSEVVQFEEDEIVVIGFGQDLPIGEGVLKMDFTGTLNDQMRGFYRSKYEYKGESRNMAVTQFEAADARRCFPCWDEPAFKAKFKLTLEVPSELVALSNMPVIKETVHGPLKTVYYEESPLMSTYLVAIVVGLFDYIEGSTLEGTKVRVYTQVGKSNQGKFALDVAVKSLDLFKDYFATPYPLPKLDMVAIPDFAAGAMENYGLVTYRETALLYDELLSSASNKQQVAITVAHELAHQWFGNLVTMEWWTHLWLNEGFASWVSYLAVEALFPEWNNWTQFLDETTSGLRLDALAESHPIEVDINHASEIDAIFDSISYDKGASVIRMLQSYLGAERFQKALASYIKKYAYSNAKTEDLWAVLEEESGEPVKDLMTTWTKQQGYPVIYAKLDGHDLHLEQAQFLSDGSSGPGLWIVPITSCCGSYDAQKKFLLKGKTDKVHIDLTASQNAGGEKGENCWIKLNVDQTGFYRVKYDDELAAGLEKAIKANKLSLMDKIGIVEDSYSLSVARKQTLTSLLRLLNAYRNESDYTVLSHVTSVCLGIDKISVDATPELSRDIKQLLINLLLSAAKTLGWDPKEGESHLDVMLRSLLLIALVKLGHDETINEGVRRFHIFIKDRKTNILPPDTRKASYLAVMRTVTTSSRAGYDALLKIYRETAEAQEKSRILGSLSSCLDKDIVLEALNFMLTDEVRNQDAFYVLGGISLEGREVAWAWLKENWDHVLKTWPSSSLISDFVKSTVSRFTTEEKAAEVSEFFAGKTKPSFERALKQSLERVRISARWIESIRSEPNLAQTVNELLQHDM
What are the official names of this protein?
Aminopeptidase M1-B, Alpha-aminoacylpeptide hydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. Cytoplasm. Note=The dileucine internalization motif may be involved in intracellular sequestration.
Protein: GABD_BACSU
Sequence: MPDQLTVYNPATGEEIKTIPQQSATEVEEAIERSHQAFKTWSKTSANERTSLLKKWYELIVEHKEELADLITKENGKPYQEAVGEVLYGAGYIEWFAEEAKRVYGRTVPAPTTGKRIVVTRQPVGPVAAITPWNFPNAMITRKAAPALAAGCTFIIKPAPDTPLSAYELARLAYEAGIPKDVLQVVIGDGEEIGNVFTSSPKIRKITFTGSTPVGKILMKNSADTVKHVSMELGGHAPLIVDEDADIDLAVEQAMASKYRNAGQTCVCANRLIVHESIKDEFAAKLSEQVSKLKVGNGLEEGVNVGPIINKRGFEKIVSQIDDAVEKGAKVIAGGTYDRNDDKGCYFVNPTVLTDVDTSMNIMHEETFGPVAPIVTFSDIDEAIQLANDTPYGLAAYFFTENYRRGIYISENLEYGIIGWNDGGPSAVQAPFGGMKESGIGREGGSEGIEPYLETKYLSIGL
What is the function of this protein?
Catalyzes the NADP(+) dependent oxidation of succinate semialdehyde to succinate.
What are the official names of this protein?
Succinate-semialdehyde dehydrogenase [NADP(+)], SSDH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: VPU_HV1Z3
Sequence: MSILQIVAIVAIIVALILAIVVWTIVYIEYKRLLRQRKIDWLIDRIRERAEDSGNESEGDTEELSTLVEMEPDNFRNDNDM
What is the function of this protein?
Enhances virion budding by targeting host CD4 and Tetherin/BST2 to proteasome degradation.  Degradation of CD4 prevents any unwanted premature interactions between viral Env and its host receptor CD4 in the endoplasmic reticulum.  Degradation of antiretroviral protein Tetherin/BST2 is important for virion budding, as BST2 tethers new viral particles to the host cell membrane.  Mechanistically, Vpu bridges either CD4 or BST2 to BTRC, a substrate recognition subunit of the Skp1/Cullin/F-box protein E3 ubiquitin ligase, induces their ubiquitination and subsequent proteasomal degradation.  The alteration of the E3 ligase specificity by Vpu seems to promote the degradation of host IKBKB, leading to NF-kappa-B down-regulation and subsequent apoptosis.  Ion channel activity has also been suggested, however, formation of cation-selective channel has been reconstituted ex-vivo in lipid bilayers.  It is thus unsure that this activity plays a role in vivo.
What are the official names of this protein?
Protein Vpu, U ORF protein, Viral protein U.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 VPU protein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass type I membrane protein.
Protein: EUPG_PHOSX
Sequence: MNSAGPKCVTLITGANTGLGFETAKALFARPEPYHILVGCRGQISRAEDAIEELQHLFPGTASTAQPLLIDISSDKSIALAFAEVQEEFGYLDIVVNNAGADLDTAVSSGRLTKREAWNQTWDVNVTGTQLFTETFAPLLLASKTQLPRLIFITSGLSSITEHANGSSPRYALAPAGWPKPDTLFLAYRSSKSGLNMIAAEWARVLRNDGVKVFNISPGFLDTGLGDDRASAERREKRALGAIDASVGGEFCANVVEGKLDEQSWPSKALRKNTVQPW
What is the function of this protein?
Short-chain dehydrogenase/reductase; part of the gene cluster that mediates the biosynthesis of eupenifeldin, a bistropolone meroterpenoid that acts as an antitumor agent (PubMed:30980906).  The first step of eupenifeldin biosynthesis is the biosynthesis of 3-methylorcinaldehyde performed by the non-reducing polyketide synthase eupA (PubMed:30980906).  Oxidative dearomatization of 3-methylorcinaldehyde likely catalyzed by the FAD-dependent monooxygenase eupB is followed by oxidative ring expansion by the 2-oxoglutarate-dependent dioxygenase eupC to provide the first tropolone metabolite, tropolone stipitaldehyde (Probable).  In parallel, generation of sesquiterpene alpha-humulene from farnesylpyrophosphate (FPP) is catalyzed by the terpene cyclase eupE (PubMed:30980906).  The cytochrome P450 monooxygenase eupD then hydroxylates humulene to humulenol (PubMed:30980906).  The putative Diels-Alderase eupF probably catalyzes the formation of the tropolone-humulene skeleton by linking humulenol and the polyketide moiety (Probable).  The short-chain dehydrogenase/reductase eupG and the flavin-dependent monooxygenase eupH are also essential for eupenifeldin biosynthesis and are likely the additional decorating enzymes of the tropolone-humulene skeleton to produce final eupenifeldin or derivatives (Probable).
What are the official names of this protein?
Short-chain dehydrogenase/reductase eupG, Eupenifeldin biosynthesis cluster protein G.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: PSBA_OLIPU
Sequence: MTAILERRESESLWGRFCNWITSTENRLYIGWFGVLMIPTLLTATSVFIIAFIAAPPVDIDGIREPVSGSLLYGNNIISGAIIPTSAAIGLHFYPIWEAASVDEWLYNGGPYELIVLHFLLGVACYMGREWELSFRLGMRPWIAVAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANEGYRFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGIWFTALGISTMAFNLNGFNFNQSVVDSQGRVINTWADIINRANLGMEVMHERNAHNFPLDLAAVEAPSTNG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: SLNL1_RAT
Sequence: MTLRKRSAQTKMWESPVVSQGKPSLLELPLKESLPKDSGLKAVPSTHTLYVGHLNPQFSVPVLACLLRDTLERLELPVAREQIEVVRRPRNTYALVQVAAPKAVLASLPWRLQMALEEQLILKELTARGKELVLSEGLESLHHREQDDSGPSPSHSPGPSPGPSPGPSPGFRRPPLPQLADPPPNWGSAGRRQISQNRPSGVRSDSAIVHQKILGQEQLFQGAFLGSETRNMEFKRGGGEYLSLAFKHHVRRYVCAFLNSEGGSLLVGVEDSGLVQGIHCSHRDEDRTRLLVDSILQGFKPQVFPDAYTLTFIPVISTTMTSVPLKVLRLTVHTPKAQGEPQLYETDQGEVFLRRDGSIQGPLSVGAIQDWCRQKWTAELSKLEEKVDVLTLEKEQLQEQLRQRQTLSCSCCVL
What are the official names of this protein?
Schlafen-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the Schlafen family. Subgroup I subfamily.
Protein: TIG_BRASB
Sequence: MQVTETLSEGLKHEFQVSVPAADLDAKADAKLVDLKDKVRINGFRPGKVPVAHLKKIYGKSVMAETIDQTIRDTNTQIFTERGFRLATEPKVTMPTEEAEVEKILSGQSDLTYTVAVEVVPAITLADFKTFSVEKPVADITDADVDEAIKRLADANRSYAAKAEGAKAESGDRVKVNFKGTIDGVAFDGGTGEGIDVVIGSNTFIPGFEDQLIGIGVGETRTLKVAFPKNYLNNDLAGKDAEFETTATAIETPEEKVVDDEFAKTLGLESLDKLKQLMRDRLAGEFNQATRQRVKRALLDRLDETHKFDAPPSLIDEEFNLMWNSVKAEMDSSGKTFADENTTEEKAKEEYRTIADRRVRLGLVLSEIGEKNKITVTDDEVSRAVIERARSMPGREKEVWDFYRSNPQALAQLRAPIYEDKVVDFILELANVTEKKVSKDELFKDDENDKAA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: PYRF_COXBR
Sequence: MEKPDPKVIVAIDAGTVEQARAQINPLTPELCHLKIGSILFTRYGPAFVEELMQKGYRIFLDLKFYDIPQTVAGACRAVAELGVWMMNIHISGGRTMMETVVNALQSITLKEKPLLIGVTILTSLDGSDLKTLGIQEKVPDIVCRMATLAKSAGLDGVVCSAQEAALLRKQFDRNFLLVTPGIRLETDEKGDQKRVMTPRAAIQAGSDYLVIGRPITQSTDPLKALEAIDKDIKTR
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: RECR_STRP4
Sequence: MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFAKNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHGLYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLLKPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: PURQ_RUBXD
Sequence: MRVGVVVFPGSNCDRDALHAVERAGAEPVELWHADADLKGSDAVILPGGFSYGDYLRPGAIARFARVMGPLEAFAREGGPVLGVCNGFQVLCEAHLLPGALLQNRGLRFVCRRVRVRVERADTPWTAACAPGEELTLPVAHNEGNYFADPATLARLEEEGRVVLRYLENPNGSANDIAGVCSEGRNVVGLMPHPERASDPLLGSGEGLGILRSVLAGAKV
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PMO25_SCHPO
Sequence: MSFLFNKRPKSTQDVVRCLCDNLPKLEINNDKKKSFEEVSKCLQNLRVSLCGTAEVEPDADLVSDLSFQIYQSNLPFLLVRYLPKLEFESKKDTGLIFSALLRRHVASRYPTVDYMLAHPQIFPVLVSYYRYQEVAFTAGSILRECSRHEALNEVLLNSRDFWTFFSLIQASSFDMASDAFSTFKSILLNHKSQVAEFISYHFDEFFKQYTVLLKSENYVTKRQSLKLLGEILLNRANRSVMTRYISSAENLKLMMILLRDKSKNIQFEAFHVFKLFVANPEKSEEVIEILRRNKSKLISYLSAFHTDRKNDEQFNDERAFVIKQIERL
What are the official names of this protein?
Mo25-like protein.
What is the protein family that this protein belongs to?
Belongs to the Mo25 family.
Protein: TRM1_PYRWO
Sequence: MSMELFEVHEGKAKVLVPKAKTIYDSPVFYNPRMAPNRDVVVLLLNVLKPKIVLDALSATGIRGIRFALETPA
What is the function of this protein?
Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.
What are the official names of this protein?
tRNA (guanine(26)-N(2))-dimethyltransferase, tRNA 2,2-dimethylguanosine-26 methyltransferase, tRNA(guanine-26,N(2)-N(2)) methyltransferase, tRNA(m(2,2)G26)dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
Protein: SYE_TROW8
Sequence: MRDPRVRVRFCPSPTGAPHLGLVRTALFNWVFARKHGGGFIFRIEDTDATRNREESCSQLIDTLKWLGLDWDEGPDKGGQFGPYYQSQRGDIYQEVLDKLLAADLAYESFSTKEEIEKRNLEAGRPIQLGYDNYDRTLSEQTKAAMREAGRTPIIRLRMDDENIAFEDLVKGEVVFTDPIPDFALTRASGEPLYTLVNPVDDAFMKITHVLRGEDLLSSTPRQIALYKALITIGITDYVPFFGHLPIVMGEGNRKLSKRNPESDFYFYKARGFIREGLLNYLSLLGWSISNSRDTFSLSEMIHAFDVRDVRGNPARFDYKKCLAINAYHLRELNVEDFFLRLVPFVEEMLGIPLSFEQKNSLRAICPFVQGRVQLLTEAAEMVRFLLVDNISVDFAVTDKEIDVLRHCLALLNLLDTWESAQIASCIKQAIEQFDLQPKRIFSILRLAITGRRVSPPLFESMQILGRSASLNRVETFVTN
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURB_MANSM
Sequence: MQSLKPFHTFAVPAQAKNIVEITALEQLQQVWDGCRQENQPVLFLGQGSNVLFLKDFAGTVLINRLMGIEHNEDEQFHYLHVNSGENWHNLVEWSLSQSIGGLENLALIPGCAGSAPVQNIGAYGVEFKDVCDYVDVLDLNQGKQFRLTNAECEFGYRESVFKHKYAQGFIVTAVGLKLAKAWQPVLKYGTLANFDKSAVGFQQIFDEVCAVRRAKLPDPKEFGNAGSFFKNPVISAGHFALLQQEYPNIPNFPQDDGSVKLAAGWLIDQCQLKGYQIGGAAVHQNQALVLVNKGDATASDIVELAHHVRQSVAAKFDVYLSPEVRFIGELGEVNAEQAIS
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPLA_ECOK1
Sequence: MSTLRLLISDSYDPWFNLAVEECIFRQMPATQRVLFLWRNADTVVIGRAQNPWKECNTRRMEEDNVRLARRSSGGGAVFHDLGNTCFTFMAGKPEYDKTISTSIVLNALNALGVSAEASGRNDLVVKTAEGDRKVSGSAYRETKDRGFHHGTLLLNSDLSRLANYLNPDKKKLAAKGITSVRSRVTNLTELLPGITHEQVCEAITEAFFAHYGERVEAEIISPDKTPDLPNFAETFARQSSWEWNFGQAPAFSHLLDERFTWGGVELHFDVEKGHITRAQVFTDSLNPAPLEALAGRLQGCLYRADMLQQECEALLVDFPEQEKELRELSAWIAGAVR
What is the function of this protein?
Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.
What are the official names of this protein?
Lipoate-protein ligase A, Lipoate--protein ligase.
What is the protein family that this protein belongs to?
Belongs to the LplA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHC24_HUMAN
Sequence: MEPAVSLAVCALLFLLWVRLKGLEFVLIHQRWVFVCLFLLPLSLIFDIYYYVRAWVVFKLSSAPRLHEQRVRDIQKQVREWKEQGSKTFMCTGRPGWLTVSLRVGKYKKTHKNIMINLMDILEVDTKKQIVRVEPLVTMGQVTALLTSIGWTLPVLPELDDLTVGGLIMGTGIESSSHKYGLFQHICTAYELVLADGSFVRCTPSENSDLFYAVPWSCGTLGFLVAAEIRIIPAKKYVKLRFEPVRGLEAICAKFTHESQRQENHFVEGLLYSLDEAVIMTGVMTDEAEPSKLNSIGNYYKPWFFKHVENYLKTNREGLEYIPLRHYYHRHTRSIFWELQDIIPFGNNPIFRYLFGWMVPPKISLLKLTQGETLRKLYEQHHVVQDMLVPMKCLQQALHTFQNDIHVYPIWLCPFILPSQPGLVHPKGNEAELYIDIGAYGEPRVKHFEARSCMRQLEKFVRSVHGFQMLYADCYMNREEFWEMFDGSLYHKLREKLGCQDAFPEVYDKICKAARH
What is the function of this protein?
Catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis (PubMed:11519011, PubMed:21671375, PubMed:25637936, PubMed:22178193).  In addition to its cholesterol-synthesizing activity, can protect cells from oxidative stress by reducing caspase 3 activity during apoptosis induced by oxidative stress (PubMed:11007892, PubMed:22010141).  Also protects against amyloid-beta peptide-induced apoptosis (PubMed:11007892).
What are the official names of this protein?
Delta(24)-sterol reductase, 24-dehydrocholesterol reductase, 3-beta-hydroxysterol Delta-24-reductase, Diminuto/dwarf1 homolog, Seladin-1.
What is the protein family that this protein belongs to?
Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Golgi apparatus membrane; Single-pass membrane protein.
Protein: ISPD_PSEA7
Sequence: MTTSDLPAFWTVIPAAGVGSRMRADRPKQYLDLAGRTVIERTLDCFLEHPMLRGLVVCLAEDDPYWPGLDCAASRHVQRAAGGVERADSVLSGLLRLLELGARADDWVLVHDAARPNLTRGDLDRLLEELAEDPVGGLLAVPARDTLKRSDRDGRVSETIDRSVVWLAYTPQMFRLGALHRALADALVAGVAITDEASAMEWAGYAPKLVEGRADNLKITTPEDLLRLQRSFPH
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: PORP_PSEAE
Sequence: MIRRHSCKGVGSSVAWSLLGLAISAQSLAGTVTTDGADIVIKTKGGLEVATTDKEFSFKLGGRLQADYGRFDGYYTNNGNTADAAYFRRAYLEFGGTAYRDWKYQINYDLSRNVGNDSAGYFDEASVTYTGFNPVNLKFGRFYTDFGLEKATSSKWVTALERNLTYDIADWVNDNVGTGIQASSVVGGMAFLSGSVFSENNNDTDGDSVKRYNLRGVFAPLHEPGNVVHLGLQYAYRDLEDSAVDTRIRPRMGMRGVSTNGGNDAGSNGNRGLFGGSSAVEGLWKDDSVWGLEGAWALGAFSAQAEYLRRTVKAERDREDLKASGYYAQLAYTLTGEPRLYKLDGAKFDTIKPENKEIGAWELFYRYDSIKVEDDNIVVDSATREVGDAKGKTHTLGVNWYANEAVKVSANYVKAKTDKISNANGDDSGDGLVMRLQYVF
What is the function of this protein?
Anion specific, the binding site has higher affinity for phosphate than chloride ions.  Porin O has a higher affinity for polyphosphates (tripolyphosphate and pyrophosphate) while porin P has a higher affinity for orthophosphate.
What are the official names of this protein?
Porin P, Outer membrane protein D1.
What is the protein family that this protein belongs to?
Belongs to the OprO/OprP family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: SNX12_SCHPO
Sequence: MYQQHIFYFITGGIFILWILAHSFFVKIIYLWASGCLLWYCLETRTFENKNNLGTSEPFLVNPAIFQKRARQLALSKLLLRQPLYPGIPEISEEIESIISHFMQKYIKVWSYQIIPEPTISNSIESHLRKCLMVLLSRVDEIDLADVLVKTVLPLITKHLRLFVEAEQLVVGNKAVSFTDHSELSREVAAKYDHGRLHEAVLLSGNPMVAQKRYLRNWTTQVLSIILPNYYETSPLVLSLVTEVIINTTLLPLVSYISDPDFFNYLIIQASGSIIQRRRKIRRLKRAIRKQSNHFQVGARRLRLKDSQHSFEQYIHEIKKISNISDARRLRSELMVQRRQLEQTEAFDFEFKQYRERLQIAIITAEKRISLLSGTPFQHKEAVLFEQVQSLLQILSDSAAVSCFLEFMERKNRSRYLHFWLVVEGLKESQDDPLNAHMIAPFSDIVSDHTDFTAIVKSYFESVDNPLDIPKPLTNTINKFVNQSKDNLNPDLWVEARNAMLMAQEHVFDIMQNSDYSEFVNSEIYYRFLAQDVVSDHKSTNSSATFSRLEELGENIPAISKQPSYLSISSSSKSINSSPSPSIQLSVSSSISRDKNLSPLDLELDDPTYSDEEEVLFAPPGDLQLSESIDELNNNIEELKAQLNAINTLIKKAELVADQKQLKSLTKNHQEIEKAIHRKERQRDQYMSQEEDSKLFNRSRVSIDSFKISKEENTPDFAVYTIRIERLENGHVRSGWMVARRYREFAELHKQLKQTYPGVRSLKFPQKSIITSLNKNVLEYRRGALEEYLQSLFRMPEVCDSKMLRMFLSQQNITAPQMFNPKEVGKKWKQLLEVLGFEVNNSFNASNVNTNSSFSGPISEFLVELFSPNDDAKQQWLPKKTYISILEQLFGGALEKRIRLQLFQLFTPEKIYRKLREFRRGLEGKSNHDHSKDRRHSRARKPAYADRNQLKAEAGILLASMFPGYTPDIAVKRIFRILQNQSLNAHVIYTLLDEILLALKKHARSTNKAT
What are the official names of this protein?
Sorting nexin-12.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: GSA_SULIA
Sequence: MDKGRCTILNSEELWAQARQLFAGGVNSPVRAAVKPFPFYVERGKGAYIYTVEGNKFIDYVLGYGPLILGHSPESVKRKIIEQLEKGWLFGTPSKLEIELAKKISSHIPSAQKIRFVNSGTEATMAAIRLARGYSKRSKILKFSGNYHGAHDYTLVEAGSAATEYNVTTSDGIPMEIMKTIEICEFNDLDCVDKKLRNEDIAAALLEPIMGNAGVILPEKGFLSGLRELTKSYNSLLIFDEVITGFRIDIGGAQSYYQIYPDITTLGKIIGGGFPIGAVAGKAEIIDNFTPAGRVFNAGTFNANPISMIAGIATIEELEKEYPYNIANKASKTLVEELERLLKIKHTINHIGSMFQVFFGIDKVRNYSDAKRANKEYYIKFHERLLKERVFIPPSQYETIFTSAAHEDDVVNDTIDKLAKVIGELS
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPF_NOSS1
Sequence: MTMSIRIGNGYDIHRLVSDRALILGGVHIPHELGLLGHSDADVLTHAIMDAMLGALSLGDIGHYFPPTDPQWAGADSLVLLSQVNELIRTQGWRIGNIDSVVVAERPKLKPHIKTMRDKLADILQLEPNQIGVKATTNEKLGPVGREEGICAYAVVLLVSSDEIS
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: ADE_PSESM
Sequence: MYDWLNALPKAELHLHLEGSLEPELLFALAERNRIALPWNDVEALRKAYAFNNLQEFLDLYYRGADVLRTEQDFYDLTWAYLLRCKEQNVIHTEPFFDPQTHTDRGIAFEVVLAGITGALKDGKSKLGVDSGLILSFLRHLSEDEAEKTLDQALPFRDAFVAVGLDSSEMGHPPSKFQRVFDRARNEGFLTVAHAGEEGPPEYIWEALDLLKIQRIDHGVRAIEDERLMQRIIDEQIPLTVCPLSNTKLCVFDDMAQHNILDMLERGVKVTVNSDDPAYFGGYVTENFHALHTHLGMTEDQARRLAQNSLDARLVKP
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenine to hypoxanthine.  Plays an important role in the purine salvage pathway and in nitrogen catabolism.
What are the official names of this protein?
Adenine deaminase, ADE, Adenine aminohydrolase, AAH.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
Protein: RL2_DESDA
Sequence: MAVRKLKPTSAGRRFQTVSDFEEITRTRPEKSLTVGLTKKSGRNNLGRITSRRRGGGVKRLYRIIDFKRDKTGIEARVAHIEYDPNRTARIALLHYTDGEKRYILAPVGLKQGDVVMSGVNDRNGEVADIMPGNALPMQRIPVGTVIHNIELYPGKGGQLCRAAGTYAQLVAKEGKYALLRLPSGEVRKVLVTCVATVGQVGNVHHESIRLGKAGRNRWLGRRPKVRGVAMNPIDHPLGGGEGRSSGGRHPVSPWGMPAKGYKTRDKKKASSRLIVKRRGQK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: PAR1_ARATH
Sequence: MEETLATPDATRRSLSPSCSATVKSRAAGFERRTKRRLSETNASVREDREEAEEEEDEVKEKIEALQRIIPGGAALGVDALFEETAGYILSLQCQIKTIKVLTSFLQRIDQEDMKFGG
What is the function of this protein?
Atypical bHLH transcription factor that acts as negative regulator of a variety of shade avoidance syndrome (SAS) responses, including seedling elongation and photosynthetic pigment accumulation.  Acts as direct transcriptional repressor of two auxin-responsive genes, SAUR15 and SAUR68.  May function in integrating shade and hormone transcriptional networks in response to light and auxin changes.
What are the official names of this protein?
Transcription factor PAR1, Basic helix-loop-helix protein 165, AtbHLH165, bHLH 165, Protein HELIX-LOOP-HELIX 1, Protein PHYTOCHROME RAPIDLY REGULATED 1, bHLH transcription factor bHLH165.
What is the protein family that this protein belongs to?
Belongs to the bHLH protein family.
What are the subcellular locations of this protein?
Nucleus.