PharMolix/UniProtQA huggingface dataset:
Protein: RPOB_METCA
Sequence: MAYSFTEKKRIRKSFGKRQDVLEVPYLLATQVDSYRRFLQLDKQPAARSDEGLHAALKSVFPIKSHSGNIVLEYVSYRLGDPVFDVKECQQRGTTYAAPLRVLVRLVVYDKDAPVGAKVVRDIKEQEIYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDHDRGKTHSSGKLLFNARIIPYRGSWLDFEFDHKDCVYVRIDRRRKLPATVLLRALGYDNEQIIAEFFDTNRFLLSSAGIQLELIPERLRGDIASFDIRLGDQIVVEKDHRITARHIRMLQKENVNLLDVPKDYLYGKILAHNVVDTSTGELIAKVNQEITEDVYARLVAAAIPEIRTLYVNDLDRGPYISNTMRIDLTETQLDALVEIYRMMRPGEPPTKEAAQTLFENLFFSAERYDLSAVGRMKFNRRLGRTDPTGPGVLENDDIIAVLKELINIRNGGGTVDDIDHLGNRRVRSVGEMVENQFRLGLVRVERAVKERLSLPDADGLMPQEIINAKPVAASIKEFFGSSQLSQFMDQNNPLSEVTHKRRVSALGPGGLARERAGFEVRDVHTTHYGRVCPIETPEGPNIGLINSLAVYSRTNEYGFLETPYRKVIDGRVTDQIEYLSAIEEGQYYIAQASASVDENGMLKDELVSCRHKDEFTLASRENINYMDVSSKQIVSVAASLIPFLEHDDANRALMGSNMQRQAVPTLRTEKPLVGTGMERIVARDSGVAVVAKRGGTVEFVDASRIVVRVNDEETEAGVPGVDIYNLTKYTRSNQNTCINQRPLVKPGDVVARNDVLADGPSTDMGELALGQNLLVAFMPWNGYNFEDSILISERVVQDDRFTTIHIEEKTCVARDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVKAGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVPSGMDGTVIDVQVFTRDGVKKDERARQIEEAEIERVRKDLNDQLRIIEKDFYQRAEQMVLGKVADMGPGGLKRGATITREYLDSIKPAQWLEIRLQDEDVNLQIEAIAEQIAQQREEIAKRLEEKRRKITMGDDLAPGVLKMVKVYLAVKRRIQPGDKMAGRHGNKGVISRIVPVEDMPYSADGTPVDIVLNPLGVPSRMNVGQVLETHLGWAAKGVGLKIGRMLEAKAKIEEIRSFLTQVYNVSGRQEDIASLSDAEVLELAGNLQDGVPMATPVFDGATEEDIKAMLRLADLPESGQATLFDGRTGDVFDRPVTVGYMYMLKLNHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGDHRMEAAMPESFNVLIKEIRSLGINIELEQD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: Y5318_PSEFS
Sequence: MERFIENAMYASRWLLAPIYFGLSLGLLALALKFFQEVIHLLPSVFSMAESELILVLLSLIDMALVGGLLVMVMISGYENFVSQLDIDDNKEKLNWLGTMDSSSLKMKVAASIVAISSIHLLRIFMDAKNVDPQHLMWYVIIHMTFVVSAFAMGYLDKVTKH
What are the official names of this protein?
UPF0114 protein PFLU_5318.
What is the protein family that this protein belongs to?
Belongs to the UPF0114 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EGLX_ASPOR
Sequence: MSSSSFVWTVGSIALSSLITPTIADGSGSRYQLTEAWQGEKFLDHFKFFSGSDPTNGFVTYANQSYAESSGLIEVTESGSFYMGVDYKTKLSPNGPGRDSVRIESKEYYDEGLYIIDLQHMPGSVCGTWPAFWSVGPNWPYDGEIDIIEGVNKHEANEIVLHTSGSCSLSSENDMSGTMTSSECGESSGTIGCVVKGQDGTSGAPFNEKNGGVYAMEWTSSFVKIWYFARSEIPQSITEGNPDTTAFGTPMAHLQGTCDFGERFKSQKFILDTTFCGDWAGGVFGDSGCPVSDPSNPIQSCVNYVAENPAAFKEAYWEINYIKLFQTGTGHSTASVASQAETATAVASNTVDSIPSVTSTAIPETTAPAPETVSAEAPATSSAVPEPANPQTSVAGAETTAAPAPSPETTAAPASPSLDDSDGADAVSETTIYVTETTTICGASTQKGTIQTIGGGETEVSPASSTVESAATPAAPTPTSQKPVASLPGTTVNGGTPVPTDVSPETPAEETAGESGAPTPSAEQPEQPQPAATSIETGTVPPAVSNPAPTEQGTPEGASPVDATESRHDSDEPAPTSAAPIRSPSPSSWTISSSSRVASSSSFASTTSSASRTTSATKEATAPTETDSGASTGTNPESPVFTAGASKSVGISGLTGIVCGIAMAMLA
What is the function of this protein?
Mixed-linked glucanase involved in the degradation of complex natural cellulosic substrates.
What are the official names of this protein?
Probable endo-1,3(4)-beta-glucanase AO090023000083, Mixed-linked glucanase AO090023000083.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 16 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: DCD_RHOCS
Sequence: MPIMPDTWIREMATTKGMIEPFTEAQKREGVISYGLSSYGYDARVADEFKIFTNVDNAIVDPKQFDATSFVDRKTDVCIIPANSFALARTVEYFRIPRDVLVICLGKSTYARCGLIVNVTPLEPEWEGHVTLEISNTTPLPAKVYANEGLCQFLFLKGEGTCEVSYADRAGKYMRQRGVTLPRL
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: CLPX_LISMF
Sequence: MFKFNDEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCNEIIEEELGISEFVDFGEVPKPQEIRHILSDYVIGQERAKKALAVAVYNHYKRINSNETKEDEVELSKSNICLIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQSADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQELIQIDTGNILFIVGGAFDGIEQIVKNRMGEKVIGFGTDNAKLKDDETYLSRVVPEDLLKFGLIPEFIGRLPVIATLEQLDEAALVSILTEPKNALVKQYKRMLELDDVELEFEPTALIEIAKEAIERKTGARGLRSIIEQIMLEVMFEIPSRDDITKCIITEKAARGEEEPQLQLEDGSIIPIKTSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: IFC2_CAEEL
Sequence: MSTYAAYTTSTYQGRGLASGTYASGFGQLVSGMSSAGAICTTQIRDAREREKREIGLLNDRLADYIEKVRFLEAQNRCLSHDIDILRNGFSGGGHVSGLFDAEINQAKHILEQTTAHRSTFERDITGLSAEIEVFRKKWLDAVNAVKAHREDHDVDLDRLAKIEAEISLFKRKIRIVEEDVIRIRRENDGIYNEIARIKQLTHNEIALKNERSLNVSDLLQRINLLQTENNVRIEQELVFIRRDTTADNRDYFRHELQAAIRDIRADYEAISIRNRQDIEVWYREQIRKIQDESVRVNPDLYKEELISIRTTVTNVRSRLAEVEGRNFFLERLIDDLKNNEEAKFFEISLAERDAQIATLRDQCTELSIQMEKLCDNEISLRAEIERYRILLNGANVTTYTSNTHGSGSGIAVGGVVGGSTRVISQTTRTHSSSNTSYSNVPASRGGYSISGNVGGISVGGTIGSHGASAHATGGIIGSGVQAHRGSVSSLITDKPRDRVHDEKGVDQSGRHFHSWYLGTISINQVTPSYIELKNICKIRRVDVGGFRIEQSVNGQVLGSAQINVPLILDPQEVVRFNHRHGKYLGQFFMDVDAFDNSTVARTSMYNYTEPHEERAWFVYLD
What is the function of this protein?
Cytoplasmic intermediate filaments provide mechanical strength to cells.  Not essential protein, although its absence leads to mild defects in locomotion.
What are the official names of this protein?
Intermediate filament protein ifc-2, Cel IF C2, Intermediate filament protein C2, IF-C2.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENOPH_ACYPI
Sequence: MPVNENVILLDIEGTITSISFVKDTLFPYVTKVLEDYIEKYWDDESFQQDLELLRAQAVIDSNVEGFVPISTGDNAKTSVINNVLWQMTNDKKTTALKQLQGHIWKDGYESGLLRGHLYEDVLPVLNKLTDFGKKIYTYSSGSTKAQEYLFQYSMYGDVSGIFLKYFDTKMGPKGSETSYINIANEINVNCSDILFLTDVVVEAEAAVKAGCNSIFLVRPGNAPLDPEKSSKFRIIKTLDELLETE
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DEGR_BACSU
Sequence: MDDKDLKLILHKTFIEIYSDLEELADIAKKGKPSMEKYVEEIEQRCKQNILAIEIQMKIK
What is the function of this protein?
Stabilizes the phosphorylated form of DegU, leading to enhanced production of levansucrase, alkaline protease, and neutral protease.
What are the official names of this protein?
Regulatory protein DegR.
Protein: CODY_CLOAB
Sequence: MSILLNKTRKLNTILQKSGTEPVIFDDICNILSEVLECNVYVVSRKGKILGNNFSSGFECEKLKKEIIPTKKFPDSYNLKLLDCKETKANLKHTEFCTFYENEKCEFENKVSTIVPIIGNRERLGTLVLARFTKKFTDDDLVLAEYSATIVGLEILRSKNDEIEAEARKRAVVQLAIGTLSYSELEAVEHIFNELDGNEGLLVASKIADKVGITRSVIVNALRKFESAGVIESRSLGMKGTHIKILNDRLLEGLKKIK
What is the function of this protein?
DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability.  During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.
What are the official names of this protein?
Global transcriptional regulator CodY.
What is the protein family that this protein belongs to?
Belongs to the CodY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KEFC_KLEP3
Sequence: MDSHTLIQALIYLGAAALIVPIAVRLGLGSVLGYLIAGCIIGPWGLRLVTDAEAILHFAEIGVVLMLFVIGLELDPQRLWKLRASVFGGGALQMVACGVLIGLFCMLLGLRWQVAELIGMTLALSSTAIAMQAMNERNLTVSQMGRSAFAVLLFQDIAAIPLVAMIPLLAASGGATSLVAFALSALKVAAALALVVALGRYLTRPLLRFVARSGLREVFSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLFFIGVGMSIDFGTLVTHPLRIVILLVGFLAIKMLMLWLIARPLGVPRAQRRWFAVLLGQGSEFAFVVFGAARMADVLDGEWAKALTLAVALSMAATPVLLVLLTRLEKSASGQARDADEIDEEQPRVIVAGFGRFGQIAGRLLLSSGVKMVILDHDPDHVDTLRKFDMKVFYGDATRVDLLESAGAEKAEVLINAIDDPHVSLELVERVKEHFPHLQIISRARDVDHYIKLRQAGVEAPERETFEAALKSGRMTLEALGLGAYEARERADLFRRFNLQMVEEMVAMAENDAASRVAVFKRTSDMLTGIINEDRHHLSLVQRHGWQGTEEGRHTGDIADEPENKPSA
What is the function of this protein?
Pore-forming subunit of a potassium efflux system that confers protection against electrophiles.  Catalyzes K(+)/H(+) antiport.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system protein KefC, K(+)/H(+) antiporter.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SPEE2_RALSO
Sequence: MNRGNALLVLAVFVVASCGLAYELIAGALASYLLGDSILQFSSIIGAYLFAMGIGSWVSRYVADDALLARFVDLELLVGLFGGVSAAALFLLFALESAPFRLVLYALVTVIGVLVGMEIPLVMRMLHRRQAKFSDLVSRVLTFDYLGALAVSLLFPLVLAPRLGLVRTGFLFGLCNTAIAVWTLWHFRAELGLSARLRGAMAWRAGMVGAALLAGFAASDRLTHWSERALFGDEIIHAISSPYQRLVVTRWKDDLRLYINGNLQFSSRDEYRYHEALVLPALESVRGARRVLVLGGGDGLALRQILKYPQVEHVTLVDLDPRMTSLFSHAEALVALNQHAFSDPRVTVVNADAGQWLQTAADMFDVAIVDFPDPSNFSIGKLYSVPFYRLLSRHVADTGLVVIQATSPYFAPRSYWCVDATLKEAGYRTWPYHALVPSFGEWGFILAAPGRADFRPPTTYRVPTRFLDADTTHQMFSFAPDMPRPQVEPNRLNNQSLVRYFEEDWHGVLR
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase 2, Putrescine aminopropyltransferase 2, PAPT 2, Spermidine synthase 2, SPDS 2, SPDSY 2.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GAL1_CANPA
Sequence: MSVPKFNDLSFYSDPSAHKSRYANLVKTFKSKYPNDEIEFFARSPGRVNLIGDHIDYNYFPVLPMAIEVDVVAAVSTNNNDMIVIANTDSAKFPKETVSLAEEFTIDREHHTWANYFKCGLIVASKFLQEKAMTKLKGMNITFSGTVPTGGGLSSSAAFCVASTLAVLYANGVEDISKADLTRITVVSEHYLGLNNGGMDQCASVYGEQGKALFIQFKPQLKGTPFEFPVKNLTFVITNSLQVSNKYETAPIHYNLRVVEMAIAGDLLAKKLNVEGKEGIVKDSNVDTYSLRGVMDGYCGAWDGEDLDVGVVHLEKMIDVVGKTLTKEGGYTVEQCCEEMGLTPEEFHSRYLKKIPVKFDVLKLYERALHVYRESLRVLKTLQLLSTVVDASQFLQTFGSLMNESQHDLDILNESSNPKLNEICSIALANGAYGSRVTGAGWGGSIVHLTTTENLPKLTKSLEAYYKREFPGITDEEIREAVIDSKPATGSCLVKLDFSHALQG
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
Protein: RS7_LACDA
Sequence: MPRKGHVSKRDVLADPVYNSKLVTKLINHLMKDGKRAQASSILYDAFDIIKDKTGREPMDVFEEAMNNVKPVLEVKARRIGGSNYQVPVEVRPERQTTLALRWLVSYSRLRNEHTMDERLANELIDASNNTGSAVKKREDVHRMAEANRAFAHYRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: COSB_HALS3
Sequence: MMDTPEHASTSSRRQLLGMLAAGGTTAVAGCTTITGGGDTTSTGGGDSGSSSIVVGSKGYGEQVTLGYVAYELLANTTNATLVDETGFGGNAAISEAYRTGNVHAYYDYMGSLWSSHPPKHDSADFDTPDAQYDALKSEMESEHPIRILDRADWQNTWAVFVAERAVEGTGIQSISDLAAHVNSRNYDIRPAFGDGFRSRSDGLDALLDYYEFDPERVTAWASEREFLETASAQAAGTAVDEGYADLGVGYSTSAWLTDVDSVRVLDDDRNFWPFFHPVGVVHEDVATDAVVAALNTMPDAIPDAETMQALNSRAAASGNQQAAADHLQNNDFI
What is the function of this protein?
Mediates chemotaxis towards compatible osmolytes.  May function as a receptor that binds the osmolytes and transduces a signal to CosT.  Has probably no additional role in transport.
What are the official names of this protein?
Chemotactic signal transduction system substrate-binding protein CosB, Compatible solute binding protein.
What is the protein family that this protein belongs to?
Belongs to the OsmX family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Extracellular side. Note=Probably anchored to the membrane by lipids.
Protein: Y562_METJA
Sequence: MIGMNFKDPIEELLDNYFNAKKEYEKNPIEKNLNRLKKAEAKLMINYPNTNATYIYKNKKYKIIIKDSVSVIPI
What are the official names of this protein?
Uncharacterized protein MJ0562.
Protein: COMB_CLOB8
Sequence: MKIDIIISADDIVESRVRNKIAVIIDIFRATSVIITALDNGAREVIPYLTIEETLEYAKKLSRDNYILGGERKAVKIEGFDLSNSPLEYIKEKVEDKTVLMTTTNGTRALTKSMEAKRVFIGAMINGESVAKKLININDDVVIINAGTNGNFSMDDFICSGYIINRILDVNRNIELTDIAKTACMIYKENINILSYVREASHYSVMKSLGLNNDIDYCIKKSIIDIVPEYKDGKITCE
What are the official names of this protein?
Probable 2-phosphosulfolactate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the ComB family.
Protein: URK_HALSA
Sequence: MTIPSFAIGIAGGTGAGKTTVAREITDNVGESATLIPLDNYYEDLSDRPFEERANANYDHPSAFEWELLRTHIDALLSGQSIEMPQYDFERHVRKADRVVVEPTDVIVLEGILALSDETVNDMLDLHIYVETDADVRILRRIERDVVERGRELEGVMDQYLSTVKPMHEQFIEPTKRHADIIIPEGANSVAVNLLEEKVQAETSEMTAWAARDDTAFEDATYNPQ
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: U91_HHV6U
Sequence: MICLFYFNVLIIYLHTFLKNEKKNITDGLFLDSVTSQAMENKESMKKNEGEPPVWIQALTTTLSIILLVCIIMACIICSRTTEEEKSEMQSSASSVETLQSLNEAIFPKGEMNV
What are the official names of this protein?
Uncharacterized protein U91.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: EX7S_THEP1
Sequence: MNFEEMMKELEEIVNRLENEDLPLEESIKLFERGVELYRKCKEILQQNRLKIIDVMKELEGEIDASGRDQENELR
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_LEPCP
Sequence: MIQMQSRLDVADNTGAKSVMCIKVLGGSKRRYAGIGDVIKVSIKDAAPRGRVKKGEVYNAVVVRTAKGVRRQDGSLVKFDGNAAVLLNAKLEPIGTRIFGPVTRELRTERFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: A5566_ARTBC
Sequence: MKVFAYIALATVVAGANIRNHFGDNCKGGYLDYPNIAQRICASALHDKIKGAVTVAFSQLPQHSYMNGYQNTRDGGICGSRQKQQNVGNTDHKCLPKLAGGAEYAGSSWTAPGFKAASEKDMECTSEMAPHALVLNDGHKYALGGMEKDMINTLYSMAIEGKGFQELPTEFGAFEIEKEGAQQRAQEIKA
What are the official names of this protein?
Uncharacterized secreted protein ARB_05566.
Protein: COF1_RAT
Sequence: MASGVAVSDGVIKVFNDMKVRKSSTPEEVKKRKKAVLFCLSEDKKNIILEEGKEILVGDVGQTVDDPYTTFVKMLPDKDCRYALYDATYETKESKKEDLVFIFWAPESAPLKSKMIYASSKDAIKKKLTGIKHELQANCYEEVKDRCTLAEKLGGSAVISLEGKPL
What is the function of this protein?
Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity (By similarity).  Important for normal progress through mitosis and normal cytokinesis (By similarity).  In conjunction with the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions via regulation of actin dynamics (By similarity).  Required for the centralization of the mitotic spindle and symmetric division of zygotes (By similarity).  Plays a role in the regulation of cell morphology and cytoskeletal organization in epithelial cells (By similarity).  Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation (By similarity).  Required for neural tube morphogenesis and neural crest cell migration (By similarity).
What are the official names of this protein?
Cofilin-1, Cofilin, non-muscle isoform.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family.
What are the subcellular locations of this protein?
Nucleus matrix. Cytoplasm, cytoskeleton. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, lamellipodium membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, lamellipodium. Cell projection, growth cone. Cell projection, axon. Note=Colocalizes with the actin cytoskeleton in membrane ruffles and lamellipodia. Detected at the cleavage furrow and contractile ring during cytokinesis. Almost completely in nucleus in cells exposed to heat shock or 10% dimethyl sulfoxide.
Protein: ACP_NEOYE
Sequence: MQDNEIFEKVQDIVAEQLGIEKKIVTREANFSSDLGADSLDTVELVMAIEEKFSIEIPDEDAEKISNLSQVVDFIKSKLNTISV
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL15_THENN
Sequence: MRLEDLRPTPGSMKKRKRVGRGPGSGHGKTSGRGHKGQKARGTGKVHPWFEGGQTPLQRRLPKRGFKNINKKVYAVVNVKVLEEKFEANEEVTPAKLLERKIVKDMKDGIKILGDGELTKPLIVKAHAFSKSALEKIESVGGKAEVI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: RL21_CERS4
Sequence: MFAVLKTGGKQYKVQAGDVLRVEKLACEAGDKIQFNDILMVGGDSVTVGAPFVAGAAVQAEVIAQIKGEKTIHYVKRRRKHSSQRTKGHRQQLTLLRVTDVLASGADASGVAVATGTADARRAAHNASAKE
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: ATPI_PINKO
Sequence: MDIVRSPISTLNHIYDISGVEVGQHFYWQIGGFQVHGQVLITSWIVIAVLLGSATIAVRDPQTIPTGGQNFVEYILEFFRDLTRTQIGEEEYGPWVPFIGTMFLFIFVSNWSGALLPWGILKLPQGELAAPTNDINTTVALALLTSVAYFYAGLAKKGLGYFGKYIQPTPILLPINILEDFTKPLSLSFRLFGNILADELVVAVLVSPVPLVVPIPVMFLGLFTSGIQALIFATLAAAYIGESMEGHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, chloroplastic, ATP synthase F0 sector subunit a, F-ATPase subunit IV.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: THIO_HELPY
Sequence: MSHYIELTEENFESTIKKGVALVDFWAPWCGPCKMLSPVIDELASEYEGKAKICKVNTDEQEELSAKFGIRSIPTLLFTKDGEVVHQLVGVQTKVALKEQLNKLLG
What is the function of this protein?
Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
What are the official names of this protein?
Thioredoxin, Trx.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
Protein: MPCP_MOUSE
Sequence: MFSSVAHLARANPFNAPHLQLVHDGLSGPRSPPAPPRRSRHLAAAAVEEYSCEFGSMKYYALCGFGGVLSCGLTHTAVVPLDLVKCRMQVDPQKYKGIFNGFSITLKEDGVRGLAKGWAPTLIGYSMQGLCKFGFYEVFKALYSNILGEENTYLWRTSLYLASSASAEFFADIALAPMEAAKVRIQTQPGYANTLREAVPKMYKEEGLNAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECTKAEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSTASQVLQRLGFRGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKLGLTE
What is the function of this protein?
Transport of phosphate groups from the cytosol to mitochondrial matrix.  Phosphate is cotransported with H(+).  May play a role regulation of the mitochondrial permeability transition pore (mPTP) (By similarity).
What are the official names of this protein?
Phosphate carrier protein, mitochondrial, Phosphate transport protein, PTP, Solute carrier family 25 member 3.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PAND_RHOE4
Sequence: MFRTMMKSKIHRATVTHADLHYVGSVTVDQDLMDAADLLEGEQVCIVDIDNGARLETYVIAGERGTGVIGINGAAAHLVKPGDLVILIAYGVMNEQEVKEYSPRVVFVDADNKQIELGSDPAHAPEGSGLITPRMLSTLEASRESSLV
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VE7_HPV65
Sequence: MRGAAPRVADLNLELNDLVLPINLLSEEVLQPSDDESEAPEEELFPFRIDTCCYRCEVNVRITLFAVEFGLRALEQLIVDGKLTFCCTTCARTLRNGR
What is the function of this protein?
Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle.  Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication.  E7 protein has both transforming and trans-activating activities.  Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes.  Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation.  Also plays a role in the inhibition of both antiviral and antiproliferative functions of host interferon alpha.  Interaction with host TMEM173/STING impairs the ability of TMEM173/STING to sense cytosolic DNA and promote the production of type I interferon (IFN-alpha and IFN-beta).
What are the official names of this protein?
Protein E7.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E7 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=Predominantly found in the host nucleus.
Protein: MSRB_STRP3
Sequence: METSDELKQRIGELSYEVTQHAATESPFTGEYDDFFEKGIYVDIVSGEVLFSSLDKFNSGCGWPAFSKPIENRMVTNHDDSSYGMRRVEVKSREAGSHLGHVFSDGPKEAGGLRYCINSAALKFIPYDQMEKEGYAQWLTLFDET
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: HPRK_POLNA
Sequence: MKPTVVSADVLFEDHRATLKWEWVAGLGASERRFDEVAVSEARSGADLVGYLNYIHPYRVQILGEREVAYLSHVGPEDSARRISRIITLEPPVLVVADGQTAPDTLLSMCERAQLPMFATPESAAFVIDVLRAYLSRHFAERTSMHGVFMDILGMGVMITGESGLGKSELGLELISRGHGLVADDAIDLFRINQTAIEGRCPDLLQNLLEVRGIGLLDIKAIFGETAVRRKMRLKMIVHLVRRETLERDYERIPYEPLTQDVLGVPVRKVIIQVEAGRNIAVLVEAAVRNAILQLRGINTYQEFVERHRRAMEQDD
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.