PharMolix/UniProtQA huggingface dataset:
Protein: CTM1_ASHGO
Sequence: MRCGWMAGSSETVGIMDTADWYIGHGQVTVAPCVSIERSQIKSPDSGYGVFVDVDKLQEEECEAVELLRVPYGNVISVRTLMDWLSGRGDGYDASKDLIKTYLALFLEDTSNHRFVTETNMLILYLALMAILSERGYGFPDKFVIYLRDVLLQTRLLTPVLEVLTQEAGDAGAHYRNGPQEIFLSTLLQFISGAFMGCTRAVVLRVYAAVLSRCLEIPHETSPGSEDYTVSSSLVPILDFTNHSCEHRNAYFDVDRESGDVLLMLDVAACAGLGDRFEVFISYCPVEELVHFKHTYGFFPRASCGTQFWHMFLSDTWLKEERAPHGSGSLFQIYSELRVLPYIELALISGQVYVNDYCSSFPELLLPFVNIEALSDKESKLTALKGDQQLLAEAKTNFLSFLARYLDKLVANGPIRHSGPVCASLRDILLRELELSKRLRNTLQHGSAFLSSHMADTSPPYCPSPAPSPPYAYMYTSS
What is the function of this protein?
Methyltransferase which mediates trimethylation of cytochrome c (CYC1).
What are the official names of this protein?
Cytochrome c lysine N-methyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: QUEA_AFIC5
Sequence: MRTDLFDFDLPPECIALRPAEPRDSARLLLVRPNVGVEDHSVRDLPGLLAPGDQIVVNDTKVIAAQLSGRRIGGTSEPHIDVTLIKRIDGSRWQALVRPARKLSEGDVLRFGNEGRVCLLGNLDASVEAKGEAGEVTLAFAFHGPVLDQAIADLGAPPLPPYIASRRAPDDKDVGDYQTMFAKNEGAVAAPTAGLHFTPALEAALAARGIGIQRLTLHVGAGTFLPVKADDTDDHKMHSEWGTVSEETAKTLNEARAKGGRVVAVGSTSMRLLESAATEDGIIQPFTGETAIFITPGYKFRAVDVMMTNFHLPRSTLFMLVSAFSGLDTMRAAYAHAIAKGYRFYSYGDACLLFRNAGAAS
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBQ_DEHMB
Sequence: MAKLIMVQGTSSNVGKSILVTALCRIFKQDGYKVAPYKSQNMALNAFVTKEGGEIGRAQAVQAEACGIEPSVDMNPILMKPEADSRSQIIVNGKVDRTISAREYYEYAPLLLDTALAALNRLREKNDIVVIEGAGSPAEINLKQREIVNMRIAKEASAPVLLAGDIDRGGVFASLIGTIDLLEPDERYYIKGYLINKFRGDASLLKPAIDVLEDRTSIPVLGIIPYLRNMAIAQEDSVYLDECKGNLGETDLDIAVIRLPRISNYDDFDALATDGASVRFVSKTAEIGNPDLIIIPGTKSTIPDMEYLEQSGLAETIIKKARKGTHVLGVCGGYQILGKMIYDPHKTESETTELKGLGLLDTETTFEKEKATTQISGQVKFDSGLLSGLAGCAVSGYEIHMGRTRLFSAQPAFHITKTPKGPADYLDGASNAEGTVLGTYIHGIFENAAFRRGFLNAIRRHKGIPERQADYFDRDKEYDKLADIVRASIDMEKIYAILNEGIR
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: RL25_VIBA3
Sequence: MKFEAVVRTELGKGASRRLRHAGKFPAVIYGGEAAAVAIELVHADVINQMDKPEFYETITLVIDGAEVKVKPQDVQRHAFKPKVEHMDFIRI
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: ATPL_CELJU
Sequence: MTEAAALIILAGALVIGLGAIGAAIGVALLGGKFLEGAARQPELLPMLRTQFFVVMGLVDAIPMIGVGIGMYILFALGA
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SECA2_STAAN
Sequence: MKHKLDVTINELRLKSIRKIVKRINTWSDEVKSYSDDALKQKTIEFKERLASGVDTLDTLLPEAYAVAREASWRVLGMYPKEVQLIGAIVLHEGNIAEMQTGEGKTLTATMPLYLNALSGKGTYLITTNDYLAKRDFEEMQPLYEWLGLTASLGFVDIVDYEYQKGEKRNIYEHDIIYTTNGRLGFDYLIDNLADSAEGKFLPQLNYGIIDEVDSIILDAAQTPLVISGAPRLQSNLFHIVKEFVDTLIEDVHFKMKKTKKEIWLLNQGIEAAQSYFNVEDLYSEQAMVLVRNINLALRAQYLFESNVDYFVYNGDIVLIDRITGRMLPGTKLQAGLHQAIEAKEGMEVSTDKSVMATITFQNLFKLFESFSGMTATGKLGESEFFDLYSKIVVQAPTDKAIQRIDEPDKVFRSVDEKNIAMIHDIVELHETGRPVLLITRTAEAAEYFSKVLFQMDIPNNLLIAQNVAKEAQMIAEAGQIGSMTVATSMAGRGTDIKLGEGVEALGGLAVIIHEHMENSRVDRQLRGRSGRQGDPGSSCIYISLDDYLVKRWSDSNLAENNQLYSLDAQRLSQSNLFNRKVKQIVVKAQRISEEQGVKAREMANEFEKSISIQRDLVYEERNRVLEIDDAENRDFKALAKDVFEMFVNEEKVLTKSRVVEYIYQNLSFQFNKDVACVNFKDKQAVVTFLLEQFEKQLALNRKNMQSAYYYNIFVQKVFLKAIDSCWLEQVDYLQQLKASVNQRQNGQRNAIFEYHRVALDSFEVMTRNIKKRMVKNICQSMITFDKEGMPVIHFP
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 2.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: SAY1_YEAST
Sequence: MAANSGLDSKVEYYRLQENEIISAVSSEDADQNDAGFRLSTIHLHLFHGLKFAALLFTVVPVFIILDSMKIIFQRKRRFCLDHVNRSFLRQSSWILDERICQYVLNPLFVCLYPSTFSSPTYVKCNIPIEDQKSPENNIFQDHQLNAPKIVSTKFYQYVMPEGFDPTTDPVLVFYHGGGYALKLTPTSFSFLNNMRNAFPKMAILVPDYTVTATDDQSKKYPLQILQNVAIFDYVVKTMGCKNVVIMGDSAGGNAVLNIVLYLRKCHREIYPKKVIAISPWANATFFHEGEKEYMQGTQEWDGLCLKSHSMFGRMFVGNNPNVDFTSDPFVNIEKNFETKMWQDILKKCSVMITYGSDELLSFQNKILAKKMSDASEGCNHFTAKNVLVEHQGYHTGPILNYSRNMDRWTNIPSIARILEFMQS
What is the function of this protein?
Required for the deacetylation of acetylated sterols.  Involved in the resistance to eugenol and pregnenolone toxicity.
What are the official names of this protein?
Steryl acetyl hydrolase 1.
What is the protein family that this protein belongs to?
Belongs to the 'GDXG' lipolytic enzyme family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: CD4_ERYPA
Sequence: VVLGKKGDTVELTCNASQKTTTQFHWKNSNQMKILGKQGSFLTKGPSKLRDRTDSRKSLWDQGCFSMIIKNLKIEDSETYICEVEDKKEEVELLVFGLTANSDTHLLQGQSLTLTLESPPGSSPSVKCRSPRGKNIQGGRTLSVPQLERQDSGTWTCTVSQDQNTVEFKIDIVVLAFQKASSTVYKKEGEQVEFSFPLAFTLEKLTGSGELWWQAERASSSKSWITFDLKNKEVSVKRVTQDPKLQMGEKLPLHLTLPQALPHYAGSGNLTLALEAKTGKLHQEVNLVVMRATQFQENLTCEVWGPTSPKLTLSLKLENKEATISKQAKAVWVLNPEEGMWQCLLSDSGQVLLESNIKVLPTWPTPVQPMALIVLGGVAGLLLFTGLGIFFCVRCRH
What is the function of this protein?
Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses.  In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex.  The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins.  Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs).  In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex.  LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of T-helper cells.  In other cells such as macrophages or NK cells, plays a role in differentiation/activation, cytokine expression and cell migration in a TCR/LCK-independent pathway.  Participates in the development of T-helper cells in the thymus and triggers the differentiation of monocytes into functional mature macrophages.
What are the official names of this protein?
T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=Localizes to lipid rafts.
Protein: LRC39_DANRE
Sequence: MTGVTVCCGTVNSIKALWETRIKKTKDDLKKEKEQKDRRAVGRLTGAWEDRIILAKLKEKIVTEEGRVILRIEKEEWKTLPPALVQLSQIQEWQLHRIGLQRIPRFISSFQSLIVLDLSRNSVTEIPKEIGKLTRLRELLLSYNRVSYVPEELGCCENLEKLELAMNRDLDELPTQLSNLKKLSHLDLSMNQFTTIPDCVVNLPSLEWLDMGSNILETLPDNIHRMEKLHTLWLPRNELEYLPDNISRMKSLDTLVLSKNKLRDIPPLMEGMSNLRFVNFRDNPLTYDVTLPDLNEDVEEEENDREMFGREFMNFYIQEARKRGSQNFTSVLNVMLEGVSETA
What is the function of this protein?
Component of the sarcomeric M-band which plays a role in myocyte response to biomechanical stress (By similarity).  May regulate expression of other M-band proteins via an SRF-dependent pathway (By similarity).  Important for normal contractile function in heart (PubMed:20847312).
What are the official names of this protein?
Leucine-rich repeat-containing protein 39, Myosin-interacting M-band-associated stress-responsive protein, Myomasp.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere, M line.
Protein: Y3046_SHEHH
Sequence: MKVWVDADACPGVIKEILFRVADRAKVEVTLVANHWMRIPPSPFINLKTVSSGFDVADDEIVKLLSAGDLVITADIPLASEVIDKGGVALNPRGELYTEQNIKSILNMRDFMDTMRASGVQTGGPAAIGASEKQAFGNQLDRFITKHHKPS
What are the official names of this protein?
UPF0178 protein Shal_3046.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: RL33_BRUA1
Sequence: MAKATTIKIKLLSTADTGFFYVTKKNSRTMTEKMTKTKYDPIARKHVEFKETKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: FEL1A_FELCA
Sequence: MKGACVLVLLWAALLLISGGNCEICPAVKRDVDLFLTGTPDEYVEQVAQYKALPVVLENARILKNCVDAKMTEEDKENALSVLDKIYTSPLC
What are the official names of this protein?
Major allergen I polypeptide chain 1, AG4, Allergen Cat-1, Allergen Fel d I-A, Allergen FdI, Allergen Fel dI.
What is the protein family that this protein belongs to?
Belongs to the secretoglobin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CSRA_ECO81
Sequence: MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHREEIYQRIQAEKSQQSSY
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
Protein: 3609L_ASFM2
Sequence: MVLSLQTLTKKVLARQYPAQCHHHFLKCCGLWWHDGPIVYHQNQKKIWSSFFTDGVNINAALVKAVKENNYDLIVLFTEWGANIDYSLLSVNTECTRDLCRELGAKEQLKQQEVLHFFNMVKRDLTGSNIILCHEVFSHNPILETINRTKLRGIIYEQLEALMENTDILSELLTKYWYGMAVEFNLTKAIHYFYQRYAHLHQWRLMCALFYNNVFDLHELYTKEKVRMDMDEMLKWACRKNYNYLTIYYCCIVLGADLNKAMFHSIQFYNLGNIFFCIDLGADAFEEGKTVAYQNDKSFIASILSLNCYSKNDSLSLKETDPEVIKRMLKDYHSKNMSMAHKYYIKYGFDNID
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.  In addition, inhibits IFN-beta-induced IFN-stimulated genes (ISGs) transcription.  Mechanistically, degrades host STAT1 and STAT2 through apoptosis and ubiquitin-proteasome pathways respectively.
What are the official names of this protein?
Protein MGF 360-9L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 360 family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: HME30_APIME
Sequence: GPRTRRVKRSHNGKNGSPEEKRPRTAFSAEQLARLKREFAENRYLTERRRQQLSRDLGLTEAQIKIWFQNKRAKIKKASGQKNPLALQLMAQGLYNHSTVPVDEDGEEI
What are the official names of this protein?
Homeobox protein E30.
What is the protein family that this protein belongs to?
Belongs to the engrailed homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FAR5_KARBO
Sequence: TDRNFLRL
What is the function of this protein?
FMRFamides and FMRFamide-like peptides are neuropeptides.
What are the official names of this protein?
Extended FMRFamide-5, FMRFa-5.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRF amide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: THI4_ALNGL
Sequence: MASTLTSKPQRLALFENSASSFYGTPLAPSSIRVQPTKAGAKPSISMSGAPSPPYDLKAFTFDPIKESIVSREMTRRYMMDMITYADTDVVVVGAGSSGLVCYELSKNPSVQVAIIEQSVSPGGGAWLGGQLFSGMVVRKPAHLFLDELGIEYDEQDNYVVIKHAALFTSTIMSKLLARPNVKLFNAVAAEDLIVKGGRVGGVVTNWALVSMNHDTQSCMDPNVMEAKVVVSSCGHDGPFGATGVKSLRSIGMIDTVPGMKALDMNVAEDAIVRLTREIVPGMIVTGMEVAEIDGAPRMGPTFGAMMISGQKAAHLALKALGLPNALDGSYVGGIHPELILAAADSAEIADA
What is the function of this protein?
Involved in biosynthesis of the thiamine precursor thiazole.  Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate.  The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate.  The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme.  May have additional roles in adaptation to various stress conditions and in DNA damage tolerance.
What are the official names of this protein?
Thiamine thiazole synthase, chloroplastic, Thiazole biosynthetic enzyme.
What is the protein family that this protein belongs to?
Belongs to the THI4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SYDND_HELP2
Sequence: MRSHFCTEISEKDVGKTIKVAGWCNTYRDHGGVVFIDLRDKSGLVQLVCDPSSKAYEKALEVRSEFVLVAKGRVRLRGAGLENPKLKTGKIEIVLEELVIENKSATPPIEIGNKSVNEDLRLKYRYLDLRSLNAYEIFKLRSEVALITRNTLAQKGFLEIETPILSKTTPEGARDYLVPSRVHEGEFFALPQSPQLFKQLLMVGGMDRYFQIARCFRDEDLRADRQPEFTQIDAEMSFCDENDVMGVVEDLLQEIFKAIGHTISKPFKRMPYKEAMENYGSDKPDLRFELPLIEVGDCFIDSSNAIFSNIAKDPKNQRIKALNVKGADALFSRSVLKELEEFVRQFGAKGLAYLQIKEDGIKGPLVKFLSEKGLKNILEKTGAKIGDIVFFGAGDKKIVLDYMGRLRLKVAETLDLIDKDALNFLWVVNFPMFEKTENGYHAAHHPFTMPKNIECEDIEEVEAHAYDVVLNGVELGGGSIRIHKEEMQKKVFEKINIHEEEAQKKFGFLLEALKFGAPPHGGFAIGFDRLIMLMTKSNSIRDVIAFPKTQKASCLLTNAPSPINEEQLRELHIRLRK
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLO1_CAEEL
Sequence: MGEIYSPSQSKGFNQPYGYPMNCNLSRVFMEMTEEDRKCLEERKYWCFLLSSITTFCASMILVVIWRVVTHLCCQRREKEFVEPIPAPEAVQINMNGSKHAPSETDPFLKQQEEKHLGWMTEAKDWAGELISGQSLTGRFLVLLVFILSIGSLIIYFYDASFQNFQVETCIPWQDSPSQQIDLGFNIFFLVYFFIRFIAASDKVWFLLEMYSWIDFFTIPPSFVAIYLQRNWLGFRFLRALRLMTVPDILQYLNILKTSSSIRLTQLVTIFVAVCLTGAGLVHLLENSGDFFKGFINPHRITYADSVYFVLVTMSTVGYGDIYCTTLCGRLFMIFFILFGLAMFASYVPEIADLIGNRQKYGGEYKGEHGKKHIVVCGHITYDSVSHFLQDFLHEDRDDVDVEVVFLHRVVPDLELEGLFKRHFTKVEFFTGTVMDSLDLSRVKIGDADACLVLANKYSTNPDAEDAANIMRVISIKNYSSDIRVIVQLMQYHNKAYLLNIPSWDWKRGDDVICLAELKLGFIAQSCLAPGFSTMMANLFAMRSFKTSQTTPDWLNLYLCGAGMEMYTDTLSHSFVGMTFPEAVDLLFNRLGLLLLAIELKDEENKECNIAINPGPHIVIQPQTQGFFIAQSADEVKRAFFWCKQCHDDIKDVSLIKKCKCKNLALFRRNTKHSTAARARATDVLQQFQPQAPAGPMGHLGQQVQLRMINQQSSTSDTHLNTKSLRFAYEIKKLMPSSGGRRNSMSIPPDGRGVDFSKDFEQQFQDMKYDSTGMFHWCPSRNLEDCVLERHQAAMTVLNGHVVVCLFADQDSPLIGLRNFIMPLRSSNFHYHELKHVVIVGDLEYLRKEWKTLYNLPKISILNGSPLSRADLRAVNINLCDMCVIISARVPNTEDTTLADKEAILASLNIKAMQFDDTLGFFPMRHQTGDRSPLGSPISMQKKGAKFGTNVPMITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAISVLDSLMSTTYFNDSALTLIRTLVTGGATPELELILAEGAGLRGGYSTPETLSNRDRCRIAQISLQDNPYDGVVHNTTYGAMFTIALRRYGQLCIGLYRLHDQDNPDSMKRYVITNPPAELRIKNTDYVYVLEQFDPGLEYEPGKRHF
What is the function of this protein?
Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+) (PubMed:11738032).  Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane (PubMed:11738032).  It therefore contributes to repolarization of the membrane potential (PubMed:11738032).  Essential for the regulation of neurotransmitter release at synapses (PubMed:11738032, PubMed:28168949).
What are the official names of this protein?
Calcium-activated potassium channel slo-1, BK channel, Maxi K channel, MaxiK, Slo homolog, Slowpoke protein 1.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. Slo sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Synapse.
Protein: TMPSD_MOUSE
Sequence: MDRGSHRNSSPARTPPQASPARTSPARAPPQASPARTPPQASPARTPPQASPARAPPPQASPARASPARAPPSRSSSGRSSSARSASTTSSPTRVYLVRATPVGAVPIRASPARSAPATRATRESPGLSFPKFSWQETQRQLPLIGCVILLISLVISLILLFYFWRGHTGIKYKEPLESCPIHAVRCDGVVDCKMKSDELGCVRFDWDKSLLKVYSGSSGEWLPVCSSSWNDTDSKRTCQQLGFDSAYRTTEVAHRDITSSFLLSEYNTTIQESLYRSQCSSRRYVSLQCSHCGLRAMTGRIVGGALTSESKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKLLEGWKVYAGTSNLHQLPEAASISQIIINGNYTDEQDDYDIALIRLSKPLTLSAHIHPACLPMHGQTFGLNETCWITGFGKTKETDEKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQKNKPGVYTKVTEVLPWIYRKMESEVRFRKS
What are the official names of this protein?
Transmembrane protease serine 13, Membrane-type mosaic serine protease, Mosaic serine protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: CYPR_DROME
Sequence: MKSLLNRIILCSAFLAVASGLSFTVTSRIYMDVKHNKKPVGRITFGLFGKLAPKTVANFRHICLRGINGTSYVGSRFHRVVDRFLVQGGDIVNGDGTGSISIYGDYFPDEDKALAVEHNRPGYLGMANRGPDTNGCQFYVTTVGAKWLDGKHTVFGKVLEGMDTIYAIEDVKTDTDDFPVEPVVISNCGEIPTEQFEFYPDDFNILGWIKAAGLPVTSSFCVLLIFHYFFRQLNMYC
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.  Acts on the folding of rhodopsin RH1 and RH2 (but not RH3) and is required for visual transduction.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase, rhodopsin-specific isozyme, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family.
What are the subcellular locations of this protein?
Membrane; Single- pass membrane protein.
Protein: SYGB_ACIB5
Sequence: MSKHTVLFELGCEELPPKSLKTLRDALQAETVKGLNEAGLNFASVEAYAAPRRLALKIVDVDAAQADTQKRFDGPAVQAAYDAEGKPTKALEGFMRGQGITVEQLSTFQAGKVEKVCYLKDVKGQSLDTLLPQILQTALDNLPIAKRMRSAASRTEFVRPVKWVVLLKDDQVIEATIQDHKAGNVTYGHRFHAPEAVTLAHANDYLAALEKAYVVANFEKRQATIQEQVKKLADEVNATAIVPADLLDEVTSLVEWPVALRATFEERYLAVPQEALITTMQDNQKYFCLINAEGKLQPYFITVSNIESKDPTQIIEGNEKVVRPRLSDAEFFFLQDQKQPLASRKEKLANMVFQAQLGTLWDKSTRIAKLAVALSSITGANPADAEKAALLAKCDLTSELVGEFPELQGIAGTYYARIEGENTEVSEALGEQYLPKFAGDVLPKTKTGTTIALSDRLDTLVGIFGIGQAPTGSKDPFALRRSAIGILRLIIENELDVTIEELVNLALQGYGDIVKDHDKTRADAVAFLEGRYRAKYEDQGVAVDVLQAVQALAPKSPLDFDKRVNAVNHFRTLPEAAALAAANKRVANILAKEATPEGSVVEANLVEDAEKALFAELQAVTPVVEPLLAAKDYTAALSKLAALRAPIDAFFDGVMVMADDAGLKANRLRLLAQLRNLFTAVADVSVLQG
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IMDH_DROME
Sequence: MESTTKVKVNGFVESTSSSAAPAIQTKSTTGFDAELQDGLSCKELFQNGEGLTYNDFLILPGYIDFTAEEVDLSSPLTKSLTLRAPLVSSPMDTVTESEMAIAMALCGGIGIIHHNCTPEYQALEVHKVKKYKHGFMRDPSVMSPTNTVGDVLEARRKNGFTGYPVTENGKLGGKLLGMVTSRDIDFRENQPEVLLADIMTTELVTAPNGINLPTANAILEKSKKGKLPIVNQAGELVAMIARTDLKKARSYPNASKDSNKQLLVGAAIGTRSEDKARLALLVANGVDVIILDSSQGNSVYQVEMIKYIKETYPELQVIGGNVVTRAQAKNLIDAGVDGLRVGMGSGSICITQEVMACGCPQATAVYQVSTYARQFGVPVIADGGIQSIGHIVKAIALGASAVMMGSLLAGTSEAPGEYFFSDGVRLKKYRGMGSLEAMERGDAKGAAMSRYYHNEMDKMKVAQGVSGSIVDKGSVLRYLPYLECGLQHSCQDIGANSINKLRDMIYNGQLRFMKRTHSAQLEGNVHGLFSYEKRLF
What is the function of this protein?
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
What are the official names of this protein?
Inosine-5'-monophosphate dehydrogenase, IMP dehydrogenase, IMPD, IMPDH, Protein raspberry.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TWF1_BOVIN
Sequence: MSHQTGIQASEDVKDIFARARNGKYRLLKISIENEKLVIGSCRKPSDSWDQDYDSFVLPLLEDKQPCYVLFRLDSQNAQGYEWIFIAWSPDHSHVRQKMLYAATRATLKKEFGGGHIKDEMFGTVKEDVSLHGYKKYLLSQSSPAPLTAAEEELRQIKINEVQTDVSVDAKHQTLQGVAFPISQEAFQALEKLNNRQLNYVQLEIDIKNEIIILANTINTELKDLPKRIPKDAARYHFFLYKHSHEGDYLESIVFIYSMPGYTCSIRERMLYSSCKSPLLEIVERQLQMDIIRKIEIDNGDELTADFLYEEVHPKQHAHKQSFAKPKGPSGKRGIRRIIRGPAETEATTE
What is the function of this protein?
Actin-binding protein involved in motile and morphological processes.  Inhibits actin polymerization, likely by sequestering G-actin.  By capping the barbed ends of filaments, it also regulates motility.  Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles (By similarity).
What are the official names of this protein?
Twinfilin-1.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Note=Diffuse cytoplasmic localization with perinuclear and G-actin-rich cortical actin structures sublocalization. Also found at membrane ruffles and cell-cell contacts (By similarity).
Protein: PCAF_ACIAD
Sequence: MKHAYIVDAIRTPFGRYAGGLAAVRADDLGAIPIAALIERNPSVNWAQVDDVIYGCANQAGEDNRNVGRMSALLAGLPVEVPATTVNRLCGSSLDAIAMAARAIKAGEAHLIIAGGVESMSRAPYVMGKSEGAFGRTQKIEDTTMGWRFINPKLKAMYGVDTMPQTAENVAEQFGIQREDQDQFAYTSQQRTAAAQAKGYFAKEIVPVTIPQRKGEPVVIDTDEHPRASTTLEGLAKLKGVVKPEGSVTAGNASGINDGAAAVLIASDEAVAQYQLKARAKIIASTTVGIEPRIMGFAPAPAIKKLLKQANLTLDQMDVIELNEAFAAQALACTRDLGLADDDARVNPNGGAIALGHPLGASGARLVTTALNQLEQSGGKYALCSMCIGVGQGIALIIERV
What is the function of this protein?
Catalyzes thiolytic cleavage of beta-ketoadipyl-CoA to succinyl-CoA and acetyl-CoA.
What are the official names of this protein?
Beta-ketoadipyl-CoA thiolase, 3-oxoadipyl-CoA thiolase.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
Protein: Y1638_ACTPJ
Sequence: MKFKSELEQAIIATVQQEVVPALGCTEPVSLALAAAVARQYLGALPDRIEAKVSPNLMKNGMGVTVPGTGTVGLTMAAAIGAIGGDPNGGLEVLKHITNEQVAQAKQMIHDHKIEVSISDTEHILYSEATLFNADQQVKVRIAAHHTNVIYIEKNGELLFSKPCVVESENAENVFANLNAKDIYDFSLNVELEKIRFIQQAAILNSALSQEGLNQDYGLHIGRTLQKQIGKGLISDDLLNRIVIETTAASDARMGGANLPAMSNSGSGNQGITATMPVVVVARHLVASEEQLIRALFLSHLMAIYIHSKLPKLSALCAVTTAAMGSCAGVAWLLTGKFEAISMAISSMIGDISGIICDGAANSCAMKVSTSVSSSYKSILMALDDTQVTGNEGIVEHQIDRSINNLCAIASRSMQYTDRQVIEIMVSKPKSL
What are the official names of this protein?
UPF0597 protein APJL_1638.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.