PharMolix/UniProtQA huggingface dataset:
Protein: DNAK_SALAI
Sequence: MARAVGIDLGTTNSCVSVLEGGEPTVIANAEGSRTTPSIVAFARNGEVLVGEVAKRQAVTNPDRTIRSVKREVGTNWSVDIDDKKYTPQEISARTLMKLKRDAESYLGEQITDAVITVPAYFNDGQRQATKEAGEIAGFNVLRIVNEPTAAALAYGLDKGSKEQTVLVFDLGGGTFDVSLLELAEGVIEVKSTSGDNLLGGDDWDQRIIDHLVKTFNGEHGIDLSQDKMAMQRLKEAAEKAKIELSAAATSNINLPYITAGAAGPLHLDVTLTRAEFQRMTQDLLDRCKGPFEQAVKDAGIKVADVEHVILVGGSTRMPAVTELVKDLTGRDPNKGVNPDEVVAVGAALQAGVLKGEVKDVLLLDVTPLSLGIETKGGIFTKLIERNTTIPTKRSEVFTTADDNQPSVLIQVFQGEREIAAYNKKLGTFELTGLPPAPRGMPQIEVTFDIDANGIVNVHAKDLGTGKEQKMTVTAGSSLPKEDIERMRRDAEEHAEEDKRRREEAETRNLAEALQWQTEKFLAESGDKLPTESRDQINEALGELRSALGGQDIEKIKSAHAQLAQVSQQAGSQLYTQQGEQAGATGAQAGGAQAGGPDDVVDAEIVDEDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: PYRH_SULIN
Sequence: MNIILKISGKFFDEDNVNNLIVLRESIRELTDNGFRVGIVTGGGSTARRYIKLAREIGIGEAYLDLLGIWASRLNAYLVMFSLQDLAYMHVPQSLEEFIQDWSHGKVVVTGGFQPGQSTAAVAALVAEASSSKTLVVATNVDGVYEKDPRVYTDVKLIPHLTTQDLRKILEGSQSVQAGTYELLDPLAIKIVERSKIRVVVMNYRKLNRIINILKGEEVSSIIEPT
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRD_BURM7
Sequence: MFSSLYPLARASLFKMDAEDAHHLTLRMLGAAGRTGLACALSPRVPDAPRTVMGLSFRNPVGLAAGLDKDGAAIDGFAALGFGFIEVGTVTPRAQPGNPRPRMFRLPEADAIINRMGFNNSGVDQFVKNVQAARYRGVLGLNIGKNADTPIERAADDYLYCLERVYPFASYVTINISSPNTKNLRQLQGAGELDALLAALKDKQRRLADLHGKLVPLALKIAPDLDDEQVKEIAATLLRHDIEGVIATNTTLSREAVKGLPHADEAGGLSGRPVFDASNAVIRKLRAELGDAVPIIGVGGIFSGEDARAKLAAGAALVQLYTGFIYRGPALVAECVKAIARGEAR
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ENO_AZOPC
Sequence: MKIVKVIGREILDSRGNPTIEVDVHLESGFIGRASVPSGASTGKNEALELRDGDKQRFLGKGVLKAVSNINKIIAPALLSRNVFDQRGIDKVMLSLDGTSTKSKLGANAILGVSLAVARAAAEYLQIPLYRYIGGVNTYILPIPMMNIINGGSHSDAPIAFQEFMIRPIGASSFREGLRMGVEVFHALKKVLHDRGLSTAVGDEGGFAPTLKGTEDALESIIQAIDNAGYKPVEDITIGLDCASSEFYKNGIYDYTKFEGTIGARRTSIQQVEYLSELVSKYPIDSIEDGMSENDWDGWKLLTSKIGNKVQLVGDDLFVTNVEFLKKGIEQGCANSILVKVNQIGSLTETLDSIEMAHRANYNSVVSHRSGETEDSTIADIAVATNSGQIKTGSLSRSDRMAKYNQLLRIEEELGDKAFYGYKALKMC
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RS4_BACAC
Sequence: MARYTGPAWKLSRRLGISLSGTGKELEKRPYAPGPHGPNQRKKLSEYGLQLQEKQKLRHMYGMTERQFRRTFDQAGKMPGKHGENFMILLEARLDNLVYRMGLARTRRAARQLVNHGHIMVDGARVDIPSYRVKPGQTISVREKSNNLVVVKEAIEVNNFVPEYLTFDADKLEATYTRHAERAELPAEINEALIVEFYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: VPS18_CAEEL
Sequence: MIKNTAKNKNGIITRATIDLKKDLKFVKLTAVSNLAVQNGEMLAAVTEKLLVHYSEGTGERHQEMSLPLNGPDHVAYIHLSRTGFHAIVSSKLGHNFYIHLKSNAFHHLKKLRCVVTAVGWNPDYSKETDTTGPILLGTAQGSIIELNVGSTGMMTTLKELTSQVAQIAEQRITSAPSPAAAITDIQLFQLADDDPKNKKWMVIIAQMARLIVLITDNEPAPVVKLGGFTSSASLQAGLMNLATEQAPSTTFHSFFTSPNTLQHTISSSKFSEKFKNHGFLTMHPTIAEPKRYAWLSPDGISIGNVNIYAERIQDVLVEEFNIEHRLIEGRLEPPTGIALTDYHVLLAYSSRVLALSLLPPHDVIFEDPWNPELGGALGFVSDNVAEFVWLYTQTFAMKYGTNDEARYIWKTYLDRGEYQKALQIARTRVAIEPDALEMVLRKQADFYIQEKNFTAAAEILAQSSEPFESVVLKFLTNSSERKMGLKTLLDKKLERLTRHEDKIRRDALVMWLLNVQLEELAEMRRLKNSNPDPAFVEKLRDTTDHVQRYFMRKNVIESIQTNRDAVYRMCVAHADFEMQLFFANAVKDLRTVIDILMLREQYFEVLEVLKNQRISELTYEMCPLLIEHIPKQVIVYLIQNQDQISPQKLTPCLSLCVKNMEMAIPAIKYLEAQFKGTQTISQNPQNLANLHNIYIHLMAKFRREKLLGYLESHGTIRSDLPYELDFAMRTCEQFKIEPCVVYLFCVAGMFGDAVEKALGFDVDLAKKCALMMEEAEANFAWLEGMEDPAATSYIRQKLDEKAKKAIWLKIGQYYVTQENNVDKCIELINESNHLLTIQDLLPIIPKFTRVGALKPIIVDFLKRNKQRLEKLERSMKEATEIASEIRDKQEKLKNRTTVVKPSDVCSHCARPISGRAFNVHSCRHFFHRECLEIAMISFLSQEEVEKMKTLIIDEERVLSQMKAEQLAGNQKGFIEKQEKYLKIAAFISNIVGAECPLCGNIAISQIDKQFLSDEEFAADLNTWLL
What is the function of this protein?
Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways (PubMed:25273556, PubMed:26783301).  Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the rab-5-to-rab-7 endosome conversion probably implicating sand-1, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion (By similarity).  The HOPS complex is proposed to be recruited to rab-7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes (By similarity).  Within the HOPS complex, contributes to the normal development of gut granules in intestinal cells of the embryo, and also promotes the trafficking of embryonic intestinal gut granules away from lysosomes (PubMed:24501423, PubMed:25273556).  The CORVET complex is proposed to function as a rab-5 effector to mediate early endosome fusion probably in specific endosome subpopulations (By similarity).  Required for fusion of endosomes and autophagosomes with lysosomes (PubMed:18923146, PubMed:26783301).  Plays a role in the degradation of apoptotic cells during programmed cell death (PubMed:18923146).
What are the official names of this protein?
Vacuolar protein sorting-associated protein 18 homolog.
What are the subcellular locations of this protein?
Cytoplasm. Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side. Early endosome. Cytoplasmic vesicle, autophagosome. Cytoplasmic vesicle, clathrin-coated vesicle.
Protein: OMCA_CHLT2
Sequence: MKKTALLAALCSVVSLSSCCRIVDCCFEDPCAPIQCSPCESKKKDVDGGCNSCNGYVPACKPCGGDTHQDAEHGPQAREIPVDGKCRQ
What is the function of this protein?
In elementary bodies (EBs, the infectious stage, which is able to survive outside the host cell) provides the structural integrity of the outer envelope through disulfide cross-links with the large cysteine-rich periplasmic protein and the major outer membrane porin.  It has been described in publications as the Sarkosyl-insoluble COMC (Chlamydia outer membrane complex), and serves as the functional equivalent of peptidoglycan (By similarity).
What are the official names of this protein?
Small cysteine-rich outer membrane protein OmcA, Small-CRP, 9 kDa cysteine-rich lipoprotein, 9kDa-CRP.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Note=The protein moiety probably penetrates into the periplasm.
Protein: DUS3_MAGO7
Sequence: MDPNATTPIPHPPELASTAEKRLIEAENGEPAAKRVRLDEDGGENARDSAVKGDAANGQEHITPAASEIKPDNRVKGQAPIKAEYLVEVIHNNGRDARDEGPDDDAAEGRTASEPSGKVARKGKKGQNQARDFGRSADSIRLCNSRMLSDEFSPKHCSFGDRCNLSHDLRKYLAEGRRPDLETFGGKCPIFEVHGWCNAGWKCLFVRSHMEEVEREDGRKELVLLRDLTRSKKPEGEASEDGPYGVVNTVASVDKHRMGRSKVDLSRSVEYSKWMDQYTNLVKQLHNARVDEKKREEELGELRATFVEPPFKPSEKRRLYFGRETPVLAPLTTQGNLPFRRLCVDLGAQGTYSEMAMAKPIVQGQQSEWALMKAHESETRPPTLSPETLASNSPIVKVYDNSRDLRFGAQISASSHPLAIKAAECLTTFLPHLRLIDLNCGCPIDMIYKAGAGSALLEQHNKIERIIRGMNAVSGEVPITCKLRIGVKENHPLAKKNIERAVFGSPDFRNQLGAPGCAAITLHGRTRQQRYKKPADWGYIAECAALIQSYRDKRDELTDTVREPDASTLAPSSEVFFLGNGDCYSHADYYKAIDESHVDTVMIGRGALIKPWVFEEIAAGQYLDKSSTERLGYIERFCRYGMEAWGADEMGIGTTRRFLLEYLSFAYRYVPIGLLERLPPAINDRPPAYRGRDDLETLMASDNYRDWIKISEMFLGPAHEGFKFQPKHKSNSYEMEAEG
What is the function of this protein?
Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.  Specifically modifies U47 in cytoplasmic tRNAs (By similarity).  Catalyzes the synthesis of dihydrouridine in some mRNAs, thereby affecting their translation (By similarity).
What are the official names of this protein?
tRNA-dihydrouridine(47) synthase [NAD(P)(+)], mRNA-dihydrouridine synthase DUS3, tRNA-dihydrouridine synthase 3.
What is the protein family that this protein belongs to?
Belongs to the Dus family. Dus3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ANR27_PONAB
Sequence: MALYDEDLLKNPFYLALQKWRPDLCSKVAQIHGIVLVPCKGSLSSSIQSTCQFESYILIPVEEHFQTLNGKDVFIQGNRIKLGAGFTCLLSVPILFEETFYNEKEESFSILCIAHPLEKRESSEEPLAPSDPFSLKTIEDVREFLGRHSERFDRNIASFHRTFRECERKSLRHHIDSANALYTKCLQQLLRDSHLKMLAKQEAQMNLMKQAVEIYVHHEIYDLIFKYVGTMEASEDAAFNKITRSLQDLQQKDIGVKPEFSFNIPRAKRELAQLNKCTSPQQKLVCLRKVVQLITQSPSQRVNLETMCADDLLSVLLYLLVKTEIPNWMANLSYIKNFRFSSSAKDELGYCLTSFEAAIEYIRQGSLSAKPPESEGFGDRLFLKQRMSLLSQMTSSPTDCLFKHIASGNQKEVERLLSQEDHDKDAVQKMCHPLCFCDDCEKLVSGRLNDPSVVTPFSRDDRGHTPLHVAALCGQASLIDLLVSKGAVVNATDYHGATPLHLACQKGYQSVTLLLLHYKASAEVQDNNGNTPLHLACTYGHEDCVKALVYYDVESCRLDIGNEKGDTPLHIAARWGYQAIIETLLQNGASPEIQNRLKETPLKCALNSKILSVMEAYHLSFERRQKSSEAPVQSLQRSVDSISQESSTSSFSSMSAGSRQEETKKDYREVEKLLRAVADGDLEMVRYLLEWTEEDLEDAEDTVSAVDPEFCHPLCQCPKCAPAQKRLAKVPASGLGVNVTSQDGSSPLYVAALHGRADLIPLLLKHGANAGARNADQAVPLHLACQQGHFQVVKCLLDSNAKPNKKDLSGNTPLIYACSGGHHEVVALLLQHGAAINTSNNKGNTALHEAVIEKHVFVVELLLLHGASVQVLNKRQRTAVDCAEQNSKIMELLQVVPSCVASLDDVAETDRKEYVTVKIRKKWNSKLYDLPDEPFTRQFYFAHSAGQFKGKTSREIMARDRSVPNLTEGSLHEPGRQSVTLRQNNLPAQSGSHAAEKGNSDWPERPRVTQTGPGHRRMLRRHTVEDAVVSQGPEAAGPLSTPQEVSASRS
What is the function of this protein?
May be a guanine exchange factor (GEF) for Rab21, Rab32 and Rab38 and regulate endosome dynamics.  May regulate the participation of VAMP7 in membrane fusion events; in vitro inhibits VAMP7-mediated SNARE complex formation by trapping VAMP7 in a closed, fusogenically inactive conformation (By similarity).  Involved in peripheral melanosomal distribution of TYRP1 in melanocytes; the function, which probably is implicating vesicle-trafficking, includes cooperation with Rab32, Rab38 and VAMP7.  Involved in the regulation of neurite growth; the function seems to require its GEF activity, probably towards Rab21, and VAMP7 but not Rab32/38.  Proposed to be involved in Golgi sorting of VAMP7 and transport of VAMP7 vesicles to the cell surface; the function seems to implicate kinesin heavy chain isoform 5 proteins, GOLGA4, RAB21 and MACF1.  Required for the colocalization of VAMP7 and Rab21, probably on TGN sites.  Involved in GLUT1 endosome-to-plasma membrane trafficking; the function is dependent of association with VPS29.  Regulates the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes (By similarity).
What are the official names of this protein?
Ankyrin repeat domain-containing protein 27.
What are the subcellular locations of this protein?
Early endosome. Late endosome. Cytoplasmic vesicle membrane. Lysosome. Cell membrane. Melanosome. Note=Colocalizes with VAMP7 in transport vesicles in the shaft of hippocampal neurons (By similarity).
Protein: SYT_STAA8
Sequence: MEQINIQFPDGNKKAFDKGTTTEDIAQSISPGLRKKAVAGKFNGQLVDLTKPLETDGSIEIVTPGSEEALEVLRHSTAHLMAHAIKRLYGNVKFGVGPVIEGGFYYDFDIDQNISSDDFEQIEKTMKQIVNENMKIERKVVSRDEVKELFSNDEYKLELIDAIPEDENVTLYSQGDFTDLCRGVHVPSTAKIKEFKLLSTAGAYWRGDSNNKMLQRIYGTAFFDKKELKAHLQMLEERKERDHRKIGKELELFTNSQLVGAGLPLWLPNGATIRREIERYIVDKEVSMGYDHVYTPVLANVDLYKTSGHWDHYQEDMFPPMQLDETESMVLRPMNCPHHMMIYANKPHSYRELPIRIAELGTMHRYEASGAVSGLQRVRGMTLNDSHIFVRPDQIKEEFKRVVNMIIDVYKDFGFEDYSFRLSYRDPEDKEKYFDDDDMWNKAENMLKEAADELGLSYEEAIGEAAFYGPKLDVQVKTAMGKEETLSTAQLDFLLPERFDLTYIGQDGEHHRPVVIHRGVVSTMERFVAFLTEETKGAFPTWLAPKQVQIIPVNVDLHYDYARQLQDELKSQGVRVSIDDRNEKMGYKIREAQMQKIPYQIVVGDKEVENNQVNVRQYGSQDQETVEKDEFIWNLVDEIRLKKHR
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SODM1_STAAS
Sequence: MAFELPKLPYAFDALEPHFDKETMEIHHDRHHNTYVTKLNAAVEGTDLESKSIEEIVANLDSVPANIQTAVRNNGGGHLNHSLFWELLSPNSEEKGTVVEKIKEQWGSLEEFKKEFADKAAARFGSGWAWLVVNNGQLEIVTTPNQDNPLTEGKTPILGLDVWEHAYYLKYQNKRPDYIGAFWNVVNWEKVDELYNATK
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.  Catalyzes the dismutation of superoxide anion radicals into O2 and H2O2 by successive reduction and oxidation of the transition metal ion at the active site.
What are the official names of this protein?
Superoxide dismutase [Mn/Fe] 1.
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: SYDND_MICAN
Sequence: MRTHYCGDLSAIEIEKSVTLFGWVDRRRDHGGVIFIDLRDRSGIVQIVSDPQRTPASYPIAETVRNEYVLKVTGTVSQRPTESLNPRIATGEIEIYATSIEILNGVTKQLPFVVSSSESESVREDVRLRYRYLDLRRERMSQNLQLRHQVVKEMRRFLEDEQHFIEVETPILTRSTPEGARDYLVPSRVNPGQWYALPQSPQLFKQLLMVSGMDRYYQIARCFRDEDLRADRQPEFTQLDMEMSFLSLPEILALNEALIAHIFKKVKNIDISLPLPRLTYAEAMDRYGIDRPDTRFGLELVNVAEIFADSGFKVFSGAIASGGTVKVLPIPNGNEAISNVRIKPGGDLFKEATDAGAKGIAYIRVREDYDFDTIGAIKDNLTEAQKQALIEKTGAKPGHLLLFGAGDTDTVNKSLSRLRLVLGEQLGLIDPEKINLLWVTDFPMFEYNAEEKRLEALHHPFTAPNPEDLEDLAQARALAYDMIFNGIEIGGGSLRIYQREVQEKVFATIGLSPEEAYNKFGFLLEAFEYGTPPHGGIAYGLDRLVMLLAGEESIRDVIAFPKTQQASCLLTSAPSTVAAKQLKELSVASTYKPPS
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMG_SHESH
Sequence: MFDILMYLFENYVHSEVEFLVDEDELTQELTRAGFHQSEIIKALSWLENLAELQEGDTPYLCDHDQHSFRIYTQKEMDKLDVECRGFLLFLEQIKVLSVETREMVIDRVMELDETALILEDLKWVVLMVLFNAPGNESAYEQMEDLIFEQPDGRLHS
What are the official names of this protein?
Protein Smg homolog.
What is the protein family that this protein belongs to?
Belongs to the Smg family.
Protein: THIG_BURMA
Sequence: MTPLSSADTLTLHGQTFASRVLLGTSRYPSLQSLSDSIAAARPGMVTVALRRQMNAGAAEAGFFELLKRHDVPLLPNTAGCQTIAEAVTTAQMAREVFETDWIKLELIGDDYTLQPDPVGLIEAATLLVKDGFKVLPYCTEDLVIARRLLDAGCEALMPWGAPIGTGKGIVNPYGLRVLRERLPDVPLIVDAGLGVPSHACQVMEWGFDGVLLNTAVSQATHPEIMARAFARGVEAGRAAYLAGPMDARESAHASTPVVGMPFWHQDGSHA
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOB_CROS8
Sequence: MDYTLTRIDPDGENDRYPLQKQEIVTDPLEQHVHRSVYMGKLEHALHDMVNWGRKNSLWPYNFGLSCCYVEMVTSFTAVHDVARFGAEVLRASPRQADFMVVAGTPFTKMAPVIQRLYDQMLEPKWVISMGACANSGGMYDIYSVVQGVDKFLPVDVYIPGCPPRPEAYMQALMLLQESIGKERRPLSWVVGDQGVYRANMQSERERKRGERIAVTNLRTPDEI
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SERC_ESCF3
Sequence: MAQVFNFSSGPAMLPADVLKQAQQELCDWNGLGTSVMEISHRGKEFIKVAEEAEHDFRELLNVPSNYKVLFCHGGGRGQFAAVPLNILGDKTTADYVDAGYWAASAIKEAKKYCTPNVFDAKVTVDGLRAVKPMREWQLSDNAAYLHYCPNETIDGIAIDETPDFGNEVVVAADFSSTILSRPIDVSRYGVIYAGAQKNIGPAGLTIVIVREDLLGKANIACPSILDYSILNDNDSMFNTPPTFAWYLSGLVFKWLKANGGVAAMDKINQQKAELLYGAIDNSDFYRNDVAKANRSRMNVPFQLADNALDKLFLEESFAAGLHALKGHRVVGGMRASIYNAMPLEGVIALTDFMADFERRHG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLU_CUPNH
Sequence: MSHTMTPSEIVSELDKHIIGQNKAKKAVAVALRNRWRRQQVAEPLRQEITPKNILMIGPTGVGKTEIARRLAKLADAPFIKIEATKFTEVGYVGRDVDTIVRDLAEMAIKQTRESEMKKVRTKAEDAAEDRLLDVLLPPARDIGFSQPEEKDSNTRQVFRKKLREGSLDDKEIELELSAGMPSMDIMGPPGMEDMTEQIRTMFAGLGQGKKARRKMKVKEAFKLLIDEEAAKLVNDEELKHKAIANVEQNGIVFLDEIDKIASRSEIGGGEVSRQGVQRDLLPLVEGTTVSTKYGMIKTDHILFIASGAFHLSKPSDLIPELQGRFPIRVELDSLSVQDFEAILTQTDASLTKQYQALLSTESVDLVFADDGIRRLAEIAFSVNEKVENIGARRLYTVMERLLEDLSFHATKSSGETVTINAAYVDERLGDLAVNEDLSRYVL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACKR1_PAPHA
Sequence: MGNCLHPAELSPSTQNSSQLNSEDLWNFSYDGNDSFPDVDYDANLEAAAPCHSCNLLDDSALPFFILVSVLGILASGIVLFMFFRPLFHWQLCPGWPVLAQLAVGSALFSIVVPILAPGLGNTRSSALCSLGYCVWYGSAFAQALLLGCHASLGPKLGADQVPGLTLGLSVGLWGVAALLTLPVTLASGASGGLCTPVYSMELKALQATHAVACLAIFVLLPLGLFGAKGLKKALGMGPGPWMNILWAWFIFWWPHGVVLGLDFLVRSKLLLLSTCLAQQALDLLLNLAEALAILHCVATPLLLALFCHQATRTLLPSLPLPEGWSSHLDTLGSKS
What is the function of this protein?
Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis.  Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor.  Has a promiscuous chemokine-binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines.  Acts as a receptor for chemokines including CCL2, CCL5, CCL7, CCL11, CCL13, CCL14, CCL17, CXCL5, CXCL6, IL8/CXCL8, CXCL11, GRO, RANTES, MCP-1 and TARC.  May regulate chemokine bioavailability and, consequently, leukocyte recruitment through two distinct mechanisms: when expressed in endothelial cells, it sustains the abluminal to luminal transcytosis of tissue-derived chemokines and their subsequent presentation to circulating leukocytes; when expressed in erythrocytes, serves as blood reservoir of cognate chemokines but also as a chemokine sink, buffering potential surges in plasma chemokine levels (By similarity).
What are the official names of this protein?
Atypical chemokine receptor 1, Duffy antigen/chemokine receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Atypical chemokine receptor subfamily.
What are the subcellular locations of this protein?
Early endosome. Recycling endosome. Membrane; Multi-pass membrane protein. Note=Predominantly localizes to endocytic vesicles, and upon stimulation by the ligand is internalized via caveolae. Once internalized, the ligand dissociates from the receptor, and is targeted to degradation while the receptor is recycled back to the cell membrane (By similarity).
Protein: UVRC_BACSU
Sequence: MNKQLKEKLALLPDQPGCYLMKDRQQTVIYVGKAKVLKNRVRSYFTGSHDAKTQRLVTEIEDFEYIVTSSNLEALILEMNLIKKHDPKYNVMLKDDKTYPFIKLTHERHPRLIVTRNVKKDKGRYFGPYPNVQAARETKKLLDRLYPLRKCSKLPDRVCLYYHLGQCLAPCVKDISEETNRELVESITRFLRGGYNEVKKELEEKMHEAAENLEFERAKELRDQIAHIESTMEKQKMTMNDLVDRDVFAYAYDKGWMCVQVFFIRQGKLIERDVSMFPLYQEADEEFLTFIGQFYSKNNHFLPKEILVPDSIDQSMIEQLLETNVHQPKKGPKKELLMLAHKNAKIALKEKFSLIERDEERSIGAVQKLGEALNIYTPHRIEAFDNSNIQGTNPVSAMIVFIDGKPYKKEYRKYKIKTVTGPDDYGSMREVVRRRYTRVLRENLPLPDLIIIDGGKGQINAARDVIENELGLDIPIAGLAKDEKHRTSNLLIGDPLEVAYLERNSQEFYLLQRIQDEVHRFAISFHRQIRGKSAFQSVLDDIPGIGEKRKKMLLKHFGSVKKMKEASLEDIKKAGVPAAAAQLLYDKLQK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_BORPA
Sequence: MSAPTILIMAGGTGGHIMPGLAVAEVLRERGWRVLWLGNPDKMEGRLVPPRGIELVPLRFQGVRGRGAAALLKLPFLLARACAQAWRRLADIRPDVVLGMGGYVAFPGGVMAALRRMPLVVHEQNAVAGTANRWLARLARRVLSGFPGVLPRGEALGNPVRADLCALPEPAERYAGRSGALRVLVVGGSLGAHALNTTVPQALALLPEQARPQVVHQAGEQHLPALQQAYAQAGVQADCRAFIDDMAGAMAQADLLICRAGAMTVSEVAAAGVAALFVPFPHAIDDHQTANARFLSDAQAAWLQPQATLTPQWLAQWLGQRTRQELQAVAGRARTHALPRAAAHIADVCEQAARRAS
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RK16_PHAVU
Sequence: MLSPQRTRFRKQHRGRMKGISSRGNRICFGRYALQALEPAWITSRQIEAGRRAMSRNVRRGGQIWVRIFPDKPVTVRPTETRMGSGKGFPEYWVAVVKPGKILYEMGGVPENIARKAISIASSKMPIRTQFIISG
What are the official names of this protein?
50S ribosomal protein L16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.