PharMolix/UniProtQA huggingface dataset:
Protein: MOCOS_ASPNC
Sequence: MSDRGKCQYPDDVDVIREREYPLLKDTTYLDHAGTTLYAKSLIESFSRDLTSNLYGNPHSMSAPSQLSTQRVDDIRLRALRFFSADPEEFDLVFVANATAAIKLVADSFRESTPQGFWYGYHVDSHTSLVGARELAGIGSRCFVTDAEVESWISQLDTEPVQGPRLFAYPAQSNMNGRRFPRGWCGRIRESAKDTYTLLDVASLVSTSPFDLSDASAAPDFAVLSFYKIFGFPDLGALIVRKSAGHIFDKRKFFGGGTVDMVLTQGTQWHAKKQSSIHERLEDGTLPFHNIIALGSAFDTHERLFGSMDNISSHTRFLAKRLYDRMTTLRHYNGESVCHVYKPSHSDYTDPSTQGPILAFNLRSSQGAWIGKSEVEKMASVRNIQIRSGTLCNPGGTAASLNWSGADMLRHFGAGMRCGDDHDIMDGRPTGILRVSLGAMSNLTDIDTFMGFIEEFYVEKSPNVCALVPPLEANLTHRSGFHVESLSVYPIKSCGAFKVPDGKRWEIRREGLVWDREWCLIHQGTGTALNQKRYPRMALIRPFIDLSHGVLRVTCGSIRSPSQKTLEIPLDRENSNLTTTSLCQNSSKPSTVCGDQVIVQAYSSPTVSAFFSDFLGVPCTLARFPPQSSTRLAEPRRGLGSRKSPLRPAMPGAFPQDTPTPEAERNPILLSNESPILLISRSSVNRLNETIKSSPTTTNSTGRKKAVAADVFRANIVVAEDFPQPVSAGRPYIEDHWESLRIGPDNLHFNVLGSCQRCQMVCVDQLTGVRGEEPYSTLAKTRKSGNKIYFGRHLAISSNGDGNSVNSRTVMVGDVVTPSYYGP
What is the function of this protein?
Sulfurates the molybdenum cofactor.  Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.
What are the official names of this protein?
Molybdenum cofactor sulfurase, MCS, MOS, MoCo sulfurase, Molybdenum cofactor sulfurtransferase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily.
Protein: CCB2_ARATH
Sequence: MSIQICNFPFHPKFALQPRAQRSTRIFARTENDSPQSKTSDQQLNLSVLRFTFGIPGFDESYLPRWIGYGFGSLLLLNHFSASAPISESQMRSEALGLSLAAFSIALPYIGKFLKGSVVEQRSLPEEGEQVFVISSNIGDSLKEDLAWATYVLLRNTSTIAVLISVQGELCVRGYWNCPDQMSKAQLHDWFKKKVDEIGLADVKETLYFPQYAGSALSLDILPDGTRSLFVQPLVQNTNEPQKVNGFLLVASTAGYAYSDKDRAWIGAMAEKFRG
What is the function of this protein?
Required for the biogenesis and accumulation of native cytochrome b6 in the thylakoid membrane.  Controls the conversion of apocytochrome b6 to holocytochrome b6.  Required for covalent binding of the c-type heme to cytochrome b6.
What are the official names of this protein?
Protein COFACTOR ASSEMBLY OF COMPLEX C SUBUNIT B CCB2, chloroplastic, Protein HIGH CHLOROPHYLL FLUORESCENCE 208.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: CPFC2_BACCZ
Sequence: MKKKKIGLLVMAYGTPESLEDVEAYYTHIRHGRKPSEEALQDLIGRYKAIGGISPLAKITKEQAHKLTDSMNNMFTEYEFNCYLGLKHTAPFIEDAVEEMKRDGIEQAISIVLAPHYSTFSIKAYNERAIRLSEEIGGPVIEPIDQWYDEPKFISYWADQIKETFTKIEDKEKAVVIFSAHSLPEKIIAAGDPYVEQLQHTADLIAAAANIQNYTIGWQSAGNTSDPWIGPDVQDLTRELFEEHRYEAFIYCPVGFVAEHLEVLYDNDYECKVVTDELNAAYFRPNMPNAQSTFIDCLATIVSKKMKEIVDKELILNNN
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
What are the official names of this protein?
Coproporphyrin III ferrochelatase 2.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CEMA_PHAAO
Sequence: MKKKKALASLPYLVSIIFLPWWVSLSFNKCLETWVINWWNTRQSEIPLNDIQDKNVLEKFMELEELFLLDEMIKEYSETHMQRLHIGMHKETIQLVQRQNESHFHIILHFSTNLICFAILSGYFFLGNKELFIFNSWIQEFLYNLSDTIKAFSILLVTDLWIGFHSTHGWELMIGSIYNDFGLAQNDQIISGLVSTFPVILDTIVKYWIFHFLNRVSPSLVVIYHSMNE
What is the function of this protein?
May be involved in proton extrusion.  Indirectly promotes efficient inorganic carbon uptake into chloroplasts.
What are the official names of this protein?
Chloroplast envelope membrane protein.
What is the protein family that this protein belongs to?
Belongs to the Cema family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: RS7_CORA7
Sequence: MRKNAAPKRPVVKDPVYNSEQVTMLVNKILRDGKKSTAERIVYGALEVCREKTGTDPVGTLEKALGNIRPDLEVRSRRVGGATYQVPVEVKPARSNTLALRWLVTFTRQRRENSMIERLANEILDASNGLGASVKRREDTHKMAEANRAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: F209B_HUMAN
Sequence: MWTLKSSLVLLLCLTCSYAFMFSSLRQKTSEPQGKVPCGEHFRIRQNLPEHTQGWLGSKWLWLLFAVVPFVILQCQRDSEKNKEQSPPGLRGFPFRTPLKKNQNASLYKDCVFNTLNELEVELLKFVSEVQNLKGAMATGSGSNLKLRRSEMPADPYHVTICKIWGEESSS
What is the function of this protein?
May play a role in sperm acrosome biogenesis.
What are the official names of this protein?
Protein FAM209B.
What is the protein family that this protein belongs to?
Belongs to the FAM209 family.
What are the subcellular locations of this protein?
Nucleus inner membrane; Single-pass type I membrane protein.
Protein: CI040_RAT
Sequence: MAKRRAAEPLTFRVPWKRLLLSDFPEEPPLWVPPSGAARPLKRQGDAGTMAEPASAPRKRRGGGDDEPELQGRGLEPGEPPPGEQGEPQVSRAAGGGDRVESAGSPQGADEVHSQHNEDFWQYNTFQYWRNPLPPIDLAALEDVSANSLTETLEDKNEGVEIDMES
What are the official names of this protein?
Uncharacterized protein C9orf40 homolog.
Protein: RIMK_PSEE4
Sequence: MKIAVLSRNPRLYSTRRLVEAGTQRGHEVVVIDTLRAYMNIASHKPQIHYRGKPLEGFDAVIPRIGASVTFYGCAVLRQFEMMGVYPLNESVAIARSRDKLRSLQLLSRRGIGLPITGFAHSPDDIPDLIQMVNGAPLVIKVLEGTQGIGVVLCETTKAAESVIEAFMGLKQNIMVQEYIKEAGGADIRCFVVGDKVIASMKRQAKPGEFRSNLHRGGVASLIKITPEERMTAIRAAKVMGLSVAGVDILRSNHGPLVMEVNSSPGLEGIEVTTGKDVAGMIIEHLEKNSGPNQTRTKGKG
What are the official names of this protein?
Probable alpha-L-glutamate ligase.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: YQGF_RICCK
Sequence: MIIKNLQEFYRLLIPNTQLIAIDYGSKKLGIAMSNGERSIAMPLNTITVVNKTAVINSVLSIIAKYKICGVVIGLPIDMSGVVTQQTNIVMKFAEELAKYTNLPIYLQDERLTTKAANNFLKSFGVKRKDRNNNDDAVAASMILETVLDSIKRY
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WZYE_PECCP
Sequence: MTLGQFGGLFVVYLISVIFILSLTWMEFRRVRFNFNVLFSLLYLLTFYFGFPFTCVLVFRFGVDVVPVQFLLQAMLSATAFYAIYYVSYKTRLRQKTSVPRAPLLTVNRVEANLTWLLLALIAVATVGIFFLNNGFLLFKLRSYSQIFSSDVSGVALKRFFYFFIPAMLVVYFLRQTQRAWLMFLIGTVAFGMLTYVIVGGTRANLIIAFALFLFIGIVRGWITLWMLVAAGAFGIVGMFWLALKRYGLDVSGDYAFYTFLYLTRDTFSPWENLALLWQNYDKIEFQGLAPIARDFYVFIPSWLWPDRPNLVLNSANYFTWEVLNNHSGLAISPTLLGSLVVMGGVLFIPLGAIAVGLVIKWFDWVYELGKNDSNRYKAAILQAFCFGAVFNIIVLTREGVDSFVSRVVFFCLVFGLCLLVAKLLYWLLESAGLIRQRLMRMRATPLVPTPNTVPDPVIKEQL
What is the function of this protein?
Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units.
What are the official names of this protein?
Probable ECA polymerase.
What is the protein family that this protein belongs to?
Belongs to the WzyE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NDR4B_XENLA
Sequence: MSELRFPEEKPLLRGQDTEMESADTFMSAADTDWKEHDIETPYGMLHVVIRGTPKGNRPAILTYHDVGLNHKLCFNTFFNYEDMQEITKHFVVCHVDAPGQQVGASQFPQGYQYPTMEQLAAMLPSVMQHFGFQSIIGIGVGAGAYVFAKFALIFPELVEGMVLINIDPNGKGWIDWAASKLSGLTSSLPETVLSHLFSQEELMNNTELVQNYRQQISSCVNQSNLQLFWNMYNSRRDLEMSRPGTVPNAKTLRAPVMLVVGDNAPAEDSVVECNSKLDPTNTTFLKMADSGGLPQVTQPGKLTEAFKYFLQGMGYMPSASMTRLARSRTASLTSASSVDGARPRPCTQSESSDGIGQINHTMEVSC
What is the function of this protein?
Contributes to the maintenance of intracerebral BDNF levels within the normal range.  May enhance growth factor-induced ERK1 and ERK2 phosphorylation.  May attenuate growth factor-promoted ELK1 phosphorylation in a microtubule-dependent manner (By similarity).
What are the official names of this protein?
Protein NDRG4-B.
What is the protein family that this protein belongs to?
Belongs to the NDRG family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: GET2_CANAW
Sequence: MSEPVVDTAELSAEEKKRLLRERRQAKMSKGKATARLNDILSQGSSVKTSGVKSVLDQEKEATPSHDEDPEIQDITEITTPPPRTPPIGEDAPQDIDKIFQSMLQQQGQGADTAGDPFAQIMKMFNQVEGGDSPPSESATSTQDPAELKYRQELLEYNTYNQKLWKFRFLLVRVSVTLFNFFYHYINLSNFHASNYAYVRDLSSEKYPVRDFFTWFATTEVVLVAAYYSIFHSLGLFHAANQNSFVLKAMSMGSMVLPQLEHYKPLVARFLGYYELLGIVLGDLSLVIVLFGLLSFAN
What is the function of this protein?
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Together with GET1, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.
What are the official names of this protein?
Golgi to ER traffic protein 2.
What is the protein family that this protein belongs to?
Belongs to the GET2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: C71AG_ARATH
Sequence: MEMMILISLCLTTFLTILLFFKSLLKRPNSNLPPSPWRLPVIGNLHQLSLHPHRALSSLSARHGPLMLLRFGRVPVLIVSSADVAHDVMKTHDLKFANRPITKSAHKISNGGRDLVFAPYGEYWRNVKSLCTIHLLSNKMVQSSEKRREEEITLLMETLEEASLSSSSVNLSKLITNMVSDIMGKVVLGKKYSGEEGTIDVKTITKSFLDAVGLSPVGEYIPSLAWIGKITGSDGKLEKITKQFGDFIEKVLQEHEDTTADKETPDFVDMLLTIQRDETAQCQLDKSDLKVIIFEMFLGSTTTTSAVIEWAMTRLMRNPECLKKLQDEIRSVSKMNSYVSGKEVENMNYLKAVIKEVLRLHPPLPLLVPRLLSEDVKLKGYDITAGTQVIINAWAIQRDTATWGSDAQEFRPERHFDSTWDFVGRNFKYIPFGAGRRLCPGIGLGSVMASVTLANLVKRFDWRVEDGPSGYDKPDLVEGAGIDVCRKFPLVVFPSSA
What is the function of this protein?
Possesses triterpene oxidizing activity.  Catalyzes the C23 hydroxylation of marneral to form 23-hydroxymarneral.  Catalyzes the C23 hydroxylation of marnerol to form 23-hydroxymarnerol.
What are the official names of this protein?
Cytochrome P450 71A16, Marneral oxidase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CTAA_RUEPO
Sequence: MSSKRSIFEEVSDGARAAAAQPGMIDRGRGGARGAIRAWLAVLFALVVAMIVVGGLTRLTDSGLSITEWRPVTGAIPPLSEADWQAEFDKYKQIDQWRLQNQWMELADFKSIYWWEWGHRQLGRVIGLVWALGFFGFLLARKIPAGWTGRLILPGVLGGVQGAVGAWMVASGITQGEGMTSVASYRLATHLGLAFVILGLLAWSILQLGRSERDLMQARRTKEARLFGLATGWLHLAFLQILIGALVAGLDAGRNYVDWPLMAGQVIPPDPLELSPLWRNFFENPGLVQFIHRIVGYLLLAYGVMVWLRGRRSAHAQTRFAFNAGFAALSLQVVLGIVTVLYAAPWQIAILHQLLAVGVFVLILRARFLCAYPIATSIRG
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ADH_STAA8
Sequence: MRAAVVTKDHKVSIEDKKLRALKPGEALVQTEYCGVCHTDLHVKNADFGDVTGVTLGHEGIGKVIEVAEDVESLKIGDRVSIAWMFESCGRCEYCTTGRETLCRSVKNAGYTVDGAMAEQVIVTADYAVKVPEKLDPAAASSITCAGVTTYKAVKVSNVKPGQWLGVFGIGGLGNLALQYAKNVMGAKIVAFDINDDKLAFAKELGADAIINSKDVDPVAEVMKLTDNKGLDATVVTSVAKTPFNQAVDVVKAGARVVAVGLPVDKMNLDIPRLVLDGIEVVGSLVGTRQDLREAFEFAAENKVTPKVQLRKLEEINDIFEEMENGTITGRMVIKF
What are the official names of this protein?
Alcohol dehydrogenase, ADH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: K1C19_POTTR
Sequence: MTSYSYRQSSSTSTLGLGSNNAARFGSGAFRAPSIHGGSGGLGVSVSRFASSGLSGGYGGGSSSFSVGYGGADGLLAGNEKITMQNLNDRLASYLDKVRALEEANADLEVKIRDWCQKQGPGPARDYSAYMTTIQDLRDKILGATIENSKIVLQIDNARLAADDFRTKFETEEALRLSVEADINGLRRVLDELTLARADLEMQIEGLKEELAYLKKNHEEEISALSGQVGGQVSVEVDSAPGIDLAKILTDMRSQYEAMVEKNRSDAEAWFTSKTDELNQEVAVHTKLLQTSKTEVTDLRRTLQGLEIELQSQLSMKAALEGTLAETEARYGVQLSQIQALISNIESQLSDIRADMERQNQEYLLLMDIKSRLEREIATYRSLLEGHDAQDNIVPTTPKAL
What is the function of this protein?
Involved in the organization of myofibers.  Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle (By similarity).
What are the official names of this protein?
Keratin, type I cytoskeletal 19, Cytokeratin-19, CK-19, Keratin-19, K19.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: SYA_BACCN
Sequence: MKQLTGAQIRQMFLDFFKEKGHAIEPSASLVPHEDPSLLWINSGVATLKKYFDGRVIPQNPRITNAQKSIRTNDIENVGKTARHHTFFEMLGNFSIGDYFKEEAITWAWEFLTSDKWIGFDKELLSVTIHPEDEEAFTIWHEKIGVPKERIIRLEENFWDIGEGPSGPNTEIFYDRGEAYGNDPSDPELYPGGENERYLEVWNLVFSQFNHNPDGSYTPLPKKNIDTGMGLERMTSIVQNVPTNFDTDLFMPMIGATESISGEKYRSGDAEKDMAFKVIADHIRTVTFAVGDGALPSNEGRGYVLRRLLRRAVRYAKKLNMNRPFMYELVPVVGEVMKDFYPEVLEKKDFIAKVVKNEEERFHETLHDGEAILAEVIAKAKEEKTTVISGVDAFRLYDTYGFPVELTEEYAEEAGMTVDHAGFEAEMEKQRERARAARQDVDSMQVQGGVLGEIKVASEFVGYGTVATESNVVALVKNGEYTDSLQAGEEGQLMLDVTPFYAESGGQIADSGYLLTDGVKVLVKDVQKAPNGQNLHKVVVEEGVLTKDATVKAVIDTKNRSSIVKNHTATHLLHQALKDVLGTHVNQAGSLVTAERLRFDFSHFGQVQADELEKIERIVNEKIWESIDVEISQKAIEEAKEMGAMALFGEKYGDVVRVVQVGDYSLELCGGCHVDNTASIGIFKIVAESGIGAGTRRIEAVTGKAAYELMNDQVSLLKEAAGKMKTNPKDILTRVDGLFAEVKQLQKENESLAAKLSNIEAGNLTDAVVSVDGINVLATKVNVADMNNLRTMMDDLKNKLESAVIVLAAVNDDKVNILAGVTKDLVGQGYHAGKLVKEVASRCGGGGGGRPDMAQAGGKNPAQVDEALAFVQEYVKSVSK
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOY_STAA9
Sequence: MAVFKVFYQHNRDEVIVRENTQSLYVEAQTEEQVRRYLKDRNFNIEFITKLEGAHLDYEKENSEHFNVEIAK
What is the function of this protein?
A non-essential component of RNA polymerase (RNAP).
What are the official names of this protein?
DNA-directed RNA polymerase subunit epsilon, RNAP epsilon subunit, RNA polymerase epsilon subunit, Transcriptase subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit epsilon family.
Protein: TGT_TREDE
Sequence: MKEKKEIFTLLHQDAASPARTGVLELPHGKVLTPAFMPVGTAATVKAMTKDDLDEIGFEIILANTYHLFLRPGIEVIKAAGGLHGFSDWKKNFLTDSGGFQVFSLSQLRKITEEGVKFQSHIDGSRQFLSPEIAVELQTGFNSDIQMQLDICSSFGISKTQTLADLKITMNWLDRAFAAWHNTPHEYDGALFPIVQGGFFEDLRLQSLEAILKHEPRGIAIGGLSIGEPKDLYQEYLSFTAKHIPKNKPLYVMGIGTPDYILEAVKNGVDIFDCVLPSRNARNGNLFTHEGAISIKRKEYEFDFNPIDSQCKCKVCRQYTRAYLRHLFRTKEILYSMLATYHNLAFLYSMVQDIREAIQNDSFNDYYKNFLKKYENRLD
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: RLR24_PHYBB
Sequence: MRLLIWVLFVTLVTFVSNTTATSTFTDPQVTSGDIEALTHLLDVESNADAKRFLRTESKNDLKSDADTNGIDIEDEERGFIPSSITNAFSKMKTGWSNFKSNQFEKAFQRMNQKGETPTTLAKRLDIGKTAEKRFEKTYEKYTAWWINHHTNAGT
What is the function of this protein?
Effector protein that contributes to pathogen virulence (PubMed:29671919).  Targets members of the RABA GTPases subfamily to inhibit vesicular secretion, leading to an accumulation of secretory proteins in the endoplasmic reticulum (PubMed:29671919).
What are the official names of this protein?
RxLR effector protein 24.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cell membrane. Host endomembrane system. Note=The subcellular localization to plasma and vesicular membranes is most likely the result of binding of RxLR24 to membrane-localized RABA proteins.
Protein: GEMI7_HUMAN
Sequence: MQTPVNIPVPVLRLPRGPDGFSRGFAPDGRRAPLRPEVPEIQECPIAQESLESQEQRARAALRERYLRSLLAMVGHQVSFTLHEGVRVAAHFGATDLDVANFYVSQLQTPIGVQAEALLRCSDIISYTFKP
What is the function of this protein?
The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs.  Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (Sm core).  In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP.  To assemble core snRNPs, the SMN complex accepts the trapped 5Sm proteins from CLNS1A forming an intermediate.  Binding of snRNA inside 5Sm triggers eviction of the SMN complex, thereby allowing binding of SNRPD3 and SNRPB to complete assembly of the core snRNP.
What are the official names of this protein?
Gem-associated protein 7, Gemin-7, SIP3.
What is the protein family that this protein belongs to?
Belongs to the gemin-7 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus, gem. Cytoplasm. Note=Found both in the nucleoplasm and in nuclear bodies called gems (Gemini of Cajal bodies) that are often in proximity to Cajal (coiled) bodies. Also found in the cytoplasm.
Protein: DPASD_ARTSH
Sequence: MTNSTLPPAQLHHLPASSIKSGAVNGAAADPVGTNEKFLQILRAPIDYLLTIPGKDVRGKMMNAFNQWLQIPEEKLDIIKEVIKLLHTASLLIDDIQDNSRLRRGLPVAHSIFGVAQTINTANYAYFLAQQELNKLDCAAAYEVFTEELLRLHQGQGMDIYWRDSSLCPTEEEYFEMVGNKTGGLFRLAVRLMQLASNKDCDFVPFVNVLGILFQIRDDYLNLQSDLYTKNKGFGEDLTEGKFSFPIIHSIRADPASITLTSILKQRTEDEDVKRYAISYIESTGSFEHCRRKIDELVGEARMCVKDMSPEDAKVADGIMAMVGLGAGGLSI
What is the function of this protein?
Geranylgeranyl pyrophosphate synthase; part of the gene cluster that mediates the biosynthesis of the diterpenoid pyrones subglutinols A and B (PubMed:32286350).  The first step of the pathway is the synthesis of the alpha-pyrone moiety by the polyketide synthase dpasA via condensation of one acetyl-CoA starter unit with 3 malonyl-CoA units and 2 methylations (PubMed:32286350).  The alpha-pyrone is then combined with geranylgeranyl pyrophosphate (GGPP) formed by the GGPP synthase dpasD through the action of the prenyltransferase dpasC to yield a linear alpha-pyrone diterpenoid (PubMed:32286350).  Subsequent steps in the diterpenoid pyrone biosynthetic pathway involve the decalin core formation, which is initiated by the epoxidation of the C10-C11 olefin by the FAD-dependent oxidoreductase dpasE, and is followed by a cyclization cascade catalyzed by the terpene cyclase dpasB (PubMed:32286350).  The FAD-linked oxidoreductase dpasF is then involved in tetrahydrofuran (THF) ring formation at the C5 unit to complete the formation of subglutinols A and B (PubMed:32286350).  DpasF possesses also an additional catalytic ability of multi-step oxidations to generate a new DDP analog with an enone system at the C5 named FDDP A (PubMed:32286350).
What are the official names of this protein?
Geranylgeranyl pyrophosphate synthase dpasD, GGPP synthase, GGPPSase, (2E,6E)-farnesyl diphosphate synthase, Dimethylallyltranstransferase, Diterpenoid pyrone biosynthesis cluster protein D, Farnesyl diphosphate synthase, Farnesyltranstransferase, Geranylgeranyl diphosphate synthase, Geranyltranstransferase.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
Protein: RL21_PSEAB
Sequence: MYAVIVTGGKQHKVTEGEFLKVEKLDVATGEAIDFDRVLLVANGEDVKIGLPVVEGAKVTAEVVSHGRHDKVRIIKFRRRKHHMKRQGHRQWFTEIKITGIQA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: HSPQ_ECOUT
Sequence: MIASKFGIGQQVRHSLLGYLGVVVDIDPVYSLSEPSPDELAVNDELRAAPWYHVVMEDDNGLPVHTYLAEAQLSSELQDEHPEQPSMDELAQTIRKQLQAPRLRN
What is the function of this protein?
Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress.
What are the official names of this protein?
Heat shock protein HspQ.
What is the protein family that this protein belongs to?
Belongs to the HspQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTF3_CORCI
Sequence: IQSTSMDQGILTEDSMNSFIRTLIQAGIWKNKVPKQTARTKDGTQTTVKKSEAEADATASQDTRLGFQPVVSVDAELLRQQRRFSSPRVLLSENTPLEPPPLYLTEEPVVLNRTSRRKREGKSHRGEYSVCDSESRWVTDKSSAVDIRGHQVTVLGEIRMGPS
What is the function of this protein?
Seems to promote the survival of visceral and proprioceptive sensory neurons.
What are the official names of this protein?
Neurotrophin-3, NT-3.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: KHSE_KLEP3
Sequence: MVKVYAPASSANMSVGFDVLGAAVTPVDGTLLGDNVTVEAAEQFSLHNLGRFASKLPTAPQENIVYQCWESFCQEIGKTVPVTMTLEKNMPIGSGLGSSACSVVAALVAMNEFCGKPLNETRMLALMGEMEGRISGSIHYDNVAPCYLGGMQLMIEENGIISQQVPGFDEWLWVLAYPGIKVSTAEARAILPAQYRRQDCIAHGRHLAGFIHACYTRQPQLAAKLMKDVIAEPYRTKLLPGFSEARQATMEIGAQACGISGSGPTLFALCDKPDTAQRVADWLGAHYLQNQEGFVHICRLDTAGARVVG
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBS_CYAPA
Sequence: MQLRVERKFETFSYLPPLNDQQIARQLQYALSNGYSPAIEFSFTGKAEDLVWTLWKLPLFGAQSPEEVLSEIQACKQQFPNAYIRVVAFDSIRQVQTLMFLVYKPL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, RuBisCO small subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Plastid, cyanelle.