PharMolix/UniProtQA huggingface dataset:
Protein: EPCAM_RAT
Sequence: MAPPKALAFGLLLAVVTATLAAAQKDCVCNNYKLTSRCYENENGECQCTSYGTQNTVICSKLASKCLVMKAEMTHSKSGRRMKPEGAIQNNDGLYDPECDEQGLFKAKQCNGTATCWCVNTAGVRRTDKDTEITCSERVRTYWIIIELKHKERAQPYNFESLHTALQDTFASRYMLNPKFIKSIMYENNVITIDLMQNSSQKTQDDVDIADVAYYFEKDVKGESLFHSSKSMDLRVNGELLDLDPGQTLIYYVDEKAPEFSMQGLTAGIIAVIVVVVLAVIAGIVVLVISTRKRSAKYEKAEIKEMGEIHRELNA
What is the function of this protein?
May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection.  Plays a role in embryonic stem cells proliferation and differentiation.  Up-regulates the expression of FABP5, MYC and cyclins A and E (By similarity).
What are the official names of this protein?
Epithelial cell adhesion molecule, Ep-CAM, Epithelial glycoprotein 314, EGP314, Protein D5.7A, Tumor-associated calcium signal transducer 1.
What is the protein family that this protein belongs to?
Belongs to the EPCAM family.
What are the subcellular locations of this protein?
Lateral cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Note=Colocalizes with CLDN7 at the lateral cell membrane and tight junction.
Protein: PSBU_PROMM
Sequence: MKRLLSLLTGVLVMTGLLMALIFPQSAYANVSDDKLGDRGEKVDLNNSSVRAFRQFPGMFPTIAGKIVVGGPYASVSDASSVLDASQKSVFDKYKDNFTVTDQEIAVNEGFDRINDGQYR
What is the function of this protein?
Stabilizes the structure of photosystem II oxygen-evolving complex (OEC), the ion environment of oxygen evolution and protects the OEC against heat-induced inactivation.
What are the official names of this protein?
Photosystem II 12 kDa extrinsic protein, PS II complex 12 kDa extrinsic protein, PSII-U.
What is the protein family that this protein belongs to?
Belongs to the PsbU family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Lumenal side. Note=Associated with photosystem II at the lumenal side of the thylakoid membrane.
Protein: DAPH_STRSY
Sequence: MTAQKMTAQEIIAFIGNAVKKTTVKVTFEGELAGAVPAEVTKLGNVLFGDWKDVEPLLANLTENVDYVVEQDGRNSAVPLLDKRNINARIEPGAIIRDQVTIGDNAVIMMGAVINIGAEIGPGTMIDMGAILGGRATVGKNSHIGAGAVLAGVIEPASAEPVRVGDNVLVGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQTQQKTALEEALRTL
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. DapH subfamily.
Protein: RUVC_WOLSU
Sequence: MNILGIDPGSRNCGYAILHHDPKKGNRLVEAGLIKIKERTLQHQILEFVEGIDLVLKNHSIDEVAIEDIFYAYNPKTVIKLAQFRGALSLKILQDLGNFYEYTPLQVKKALTGHGKADKSQVAFMVKRLLGLKGEIKPLDITDAIAVAITHSQRIKLGGIPT
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: SYE2_PSELT
Sequence: MTVRLRFAPSPTGYLHVGGARTALFNWLYARKMNGKFVLRIEDTDLQRSTKESEKAIIESLKWCGIDWDEGPDIGGDFGPYRQSERVSEGIYKRYAQILVEKQCAYYTVYDKVDRKKVLFNTFEYPEEYEKKGHDITISFRVPEGITKFHDLLKGNMEFQNSVIGDFVIVKSDGFPTYNFAVVIDDYLMRITHVFRGEDHLSNTPKQIMIYKALGWEIPQFMHIPLILGFDRTPLSKRHGATSVEHFRKIGILNMGLMNYLALLGWSVGEEEVFDVKEKLVNFEPESISNKGVIFDPEKLEWVNGKHMRMINIEQLWNEFVEWIKFTNRKIPHCEESYALKVLNVCREKVNTLSQLYDFSYSFFFDDYTLEERFVSEYLSTSYAKEILRKAVVLFSELKDWSIEGTEKVCRALADMKIASKNKVFQLLRGAVTGKLVTPGLFETLSILGKKRVIERFEKLLNSVDC
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 2, Glutamyl-tRNA synthetase 2, GluRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNG_XANC8
Sequence: MTEGEGRIQLEPSWKARVGEWLLQPQMQELSAFLRQRKAANARVFPPGPQIFAAFDATPFEQVKVVVLGQDPYHGEGQAHGLCFSVLPGVPVPPSLLNIYKEIQDDLGIPRPDHGYLMPWARQGVLLLNAVLTVEQGRAGAHQNKGWEGFTDHVVETLNREREGLVFLLWGSYAQSKGKVIDQARHRVFKAPHPSPLSAHRGFLGCKHFSKTNEHLQRRGLSPIDWSLPSRAALDLSLAGG
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCVA_HAEIN
Sequence: MEILMYKRLPPLNSLKSFESAARYLSFTKAADELCVTQAAVSHQIKLLEXFLGIDLFKRKNRSLELTELGKAYFVDINKILRRLNEATERLLTLKTDPHLNISVPQTFGIQWLVPHLSEFNQLYPQIEVRLTGVDQDEGLLNKEIDLAIYYGLGNWQNLQVDRLCEENLLILASPELLAENPIIQPEDLKKHTLIHIHTCDNWQAMANHLQLDDLNIQQGPLFSHTFMALQAAIHGQGIVLANRLLALQEIENGSLQAVLPTNLPDPKSFYVVNHLDRLDDQKIQAFRQWIINSIKQEENE
What is the function of this protein?
Not known, the gcv operon regulated by the E. coli homolog does not exist in H. influenzae, so it probably acts as a transcriptional regulator on some other operon.
What are the official names of this protein?
Glycine cleavage system transcriptional activator homolog.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYAY_BURP6
Sequence: MSDTDYLTRAEAVLAAVERSVDAANDGDADIDLERNGSVLTLTFENGSKIIVNLQPPMKEVWIAAKAGGFHYRFVDGAWRDTRSGDEFFAALTGYATQQAGMPIAFSA
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: PLCH2_HUMAN
Sequence: MSGPWPSPDSRTKGTVAWLAEVLLWVGGSVVLSSEWQLGPLVERCMGAMQEGMQMVKLRGGSKGLVRFYYLDEHRSCIRWRPSRKNEKAKISIDSIQEVSEGRQSEVFQRYPDGSFDPNCCFSIYHGSHRESLDLVSTSSEVARTWVTGLRYLMAGISDEDSLARRQRTRDQWLKQTFDEADKNGDGSLSIGEVLQLLHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEFCAFYKMMSTRRDLYLLMLTYSNHKDHLDAASLQRFLQVEQKMAGVTLESCQDIIEQFEPCPENKSKGLLGIDGFTNYTRSPAGDIFNPEHHHVHQDMTQPLSHYFITSSHNTYLVGDQLMSQSRVDMYAWVLQAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENHCSVIQQKKMAQYLTDILGDKLDLSSVSSEDATTLPSPQMLKGKILVKGKKLPANISEDAEEGEVSDEDSADEIDDDCKLLNGDASTNRKRVENTAKRKLDSLIKESKIRDCEDPNNFSVSTLSPSGKLGRKSKAEEDVESGEDAGASRRNGRLVVGSFSRRKKKGSKLKKAASVEEGDEGQDSPGGQSRGATRQKKTMKLSRALSDLVKYTKSVATHDIEMEAASSWQVSSFSETKAHQILQQKPAQYLRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAKFSANGGCGYVLKPGCMCQGVFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDRGEIIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPIGRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFLRGPKPGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGVADDVVPPGPGPAPEAPAQEGPGSGSPRDTRPLSTQRPLPPLCSLETIAEEPAPGPGPPPPAAVPTSSSQGRPPYPTGPGANVASPLEDTEEPRDSRPRPCNGEGAGGAYERAPGSQTDGRSQPRTLGHLPVIRRVKSEGQVPTEPLGGWRPLAAPFPAPAVYSDATGSDPLWQRLEPCGHRDSVSSSSSMSSSDTVIDLSLPSLGLGRSRENLAGAHMGRLPPRPHSASAARPDLPPVTKSKSNPNLRATGQRPPIPDELQPRSLAPRMAGLPFRPPWGCLSLVGVQDCPVAAKSKSLGDLTADDFAPSFEGGSRRLSHSLGLPGGTRRVSGPGVRRDTLTEQLRWLTVFQQAGDITSPTSLGPAGEGVAGGPGFVRRSSSRSHSRVRAIASRARQAQERQQRLQGLGRQGPPEEERGTPEGACSVGHEGSVDAPAPSKGALGPASAAAENLVLLRL
What is the function of this protein?
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes (PubMed:18361507).  This phospholipase activity is very sensitive to calcium.  May be important for formation and maintenance of the neuronal network in the postnatal brain (By similarity).
What are the official names of this protein?
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2, Phosphoinositide phospholipase C-eta-2, Phosphoinositide phospholipase C-like 4, PLC-L4, Phospholipase C-like protein 4, Phospholipase C-eta-2, PLC-eta2.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=Localized predominantly at the plasma membrane.
Protein: EIF3M_NEUCR
Sequence: MATPQLIFVDGTFAELAQEMADFVQVGEQVQPLLEQDKREDALDLIVKASHSLNAAPEKDFTPAYNLLIHLVLQSEEPKKYLPTLCANLLKPITSSPTHGFTLASNALTTIFNLLDKSNPLRFNVFMQIVRFIRQNSQFDLLKPRLKNVEGWLQEWKSDSESQRKLYVEVSDAANDGGDQEESYFYLLKALATFDRDNQDEVASDEAQKLSLRALRMAISSPTRFDFNDLRSLPSVHALSDSHPVYSQLLDIFTEQDLEDYNDFRDEHQGWIENEKLDHEKLQRKMRLLTFASLAASTPNREIPYASIAKALQIPDEDVEMWTIDVIRSKLVEGRLSQKQKVFLVHRTTYRVFGEKQWRELGTRVDQFKTVVDRLVGVVRKAQTDVEAQREREQQELERKLANAGLGESEQRGGNRGGRTGGARQTRQRTDDDD
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit M, eIF3m.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit M family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS7_CLOBA
Sequence: MQNRIAKIERNTSETKVKIDINLDGTGLNKIHTGIGFLDHMLELFSFHSNTDVYLSCDGDLNVCDHHSVEDVGIIFGKAFKEALGDKKGINRYGTFFLPMDEVLSLISLDISGRGFLVFDCEFTREKVGELSTEMIEEFFRAFALNSEITLHCKVLYGKNDHHKIESLFKGFGRALRDAKERNELNKVPSTKGIL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_RHIWR
Sequence: MSASFPHRHLTGIYGLQPHEILFLLDEAEQWIALNRATSKHDDRLAGLTLINAFFENSTRTLLSFEIAGKRLGADVVNMQVGASSVKKGETLIDTAMTLNAMRADMIVIRHQSSGAVQLIADKVDCPVLNAGDGRHEHPTQALLDALTIRRRKGRIAGLVVAICGDILHSRVARSNILALTTLGAEVRVVAPPTLMPAAIERMGAVPFHDFDAGLDGADVVMMLRLQNERMDGAYLPSPREFHALYGLTPERLERAAPDALVMHPGPMNRGVEITSSVADHPSRSAITEQVEMGVAVRMACLDVLTRRRRGVEGWA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: Y2143_MYCLE
Sequence: MSGRRRNHPGRLASIPGLRTRTGSRNQHPGIANYPADSSDFRPAQQRRALEQREQQAGQLDPARRSPSMPSANRYLPPLGQQQSEPQHNSAPPCGPYPGERIKVTRAAAQRSREMGYRMYWMVQRAATADGADKSGLTALTWPVVTNFAVDSAMAVALANTLFFAAASGESKSKVALYLLITIAPFAVIAPLIGPALDRLQHGRRVALATSFVLRTGLATLLIMNYDGATGSYPSMVLYPCALAMMVLSKSFSVLRSAVTPRVMPPSIDLVRVNSRLTVFGLLGGTIAGGAIAAGVEFVCAHLFKLPGALFVVAAITISGALLSMRIPRWVEVTAGEIPATLSYRLHRKPLRQSWPEEVKKVSGRLRQPLGRNIITSLWGNCTIKVMVGFLFLYPAFVAKEHQANGWVQLGMLGLIGTAAAIGNFAGNFTSARLQLGRPAVLVVRCTIAVTVLALAASVAGNLLMTTIATLITSGSSAIAKASLDASLQNDLPEESRASGFGRSESTLQLAWVLGGALGVMVYTDLWVGFTAVSALLILGLAQTVVSFRGDSLIPGLGGNRPVMIEQESMRRAAAVSPQ
What are the official names of this protein?
Uncharacterized protein ML2143.
What is the protein family that this protein belongs to?
To M.tuberculosis Rv0876c.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ARGJ_CLAL4
Sequence: MRISPRLFLSKAERFVPKSGVYPQGFAVGGIHCGIKKPDVLDLAMLQNTSGKDAVAAAVFTQNKFKAAPVQVSAEILEKSGGAINSLIVNSGNANAVTGTKGLEDARSMVAATDEAAKNTKTASLVMSTGVIGNRLPIGNILSGIPVLGQQLGSTHAHWLQCAQAICTTDSFPKMVSKQFSLNGNTYALAGVAKGAGMICPNMATLLGFFATDAPVSRSALQSILAFAVDRSFNSISVDGDMSTNDTIVAIANGAAGGPLIENEDTPAFAALRGEITAFAQQLASLVVRDGEGATKFITIRVVNAKSYADAKCVASTVANSSLFKTAMFGNDANWGRILCAIGYAPVSGSSVDTTRTSVSFVPSEGEPLRLLVNGEPETVDENRALEILQKRGFGGGNRFGHRRKPRGHISDV
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: P2R31_CAEEL
Sequence: MPTDEPSKRKSILPTIPTSLMLKKSNEALSDFERTFNDRVMDIFAENRRIDVEEFKKNAECFLNIIRSNKIDLNWGEGGESRYVTITRLMKILKTSPQSIKDLLPHNTVSNFVKITNYNLTIDITLLEELVRTVIHAEESYIKLLPFSENSTEISSYSLQDFVATHFIPIMIEEPENPVYYTAYAVGTIFFLLGARRRDCVYLKDLLASTLLLQLEECIHAENHCLSPPKIDVFTVAQFRTTLSEFRFLDSQRKGLLAPADLKFFRDGIFNEVFTKRIFEISITYEDGRIDFKAFVDFVTALKFRHTTASAKYHFEILDLKDDGLLDEEEIRSISSFQLQNLPDYVPEDNSVNPEVATAELRDMMRLNQNGITLEEFLANRMNSTFAGFLSNSDDYMKYERREQ
What is the function of this protein?
Regulatory subunit of phosphatase let-92 which recruits let-92/paa-1 complex to the centrosomes, thereby regulating microtubule outgrowth from centrosomes and mitotic spindle assembly ensuring the stability of kinetochore microtubules.
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A regulatory subunit rsa-1, Regulator of spindle assembly protein 1, Serine/threonine-protein phosphatase 2A 72kDa regulatory subunit rsa-1, Serine/threonine-protein phosphatase 2A regulatory subunit B'' rsa-1.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: IF3_PROM4
Sequence: MPPRPRFDRRAPVRELPNINDRIKYPQLRVVDADGTQLGVINREAALEVAQERELDLVLVSEKANPPVCRIMNYGKFKFEQEKKAKEAKKKSHQTEVKEVKMRYKIDQHDYEVRINQATRFLKAGDKVKCTVIFRGREIQHTNLAESLLARMAKDLEEQAEVQQTPKREGRNMIMFLTPRKTPLIKNEKEVTTSAKAERTIS
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLGH_PSESM
Sequence: MNRPGFPRFSVLIASLCGITLLSGCVAPTAKPNDPYYAPVLPRTPMSAASNNGAIYQAGFEQNLYGDRKAFRVGDIITITLSERMAASKAATSAMSKDSTNSIGLTSLFGSGLTTNNPIGGNDLSLSAGYNGARTTKGDGKAAQSNSLTGSVTVTVADVLPNGILSVRGEKWMTLNTGDELVRIAGLVRADDIATDNTVSSTRIADARITYSGTGAFADTSQPGWFDRFFLSPLFPF
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: G6PI_SHESA
Sequence: MTILTQSTTWQALAAHSQQIPHMRELFASDPARFSNMSLSTCGLFLDYSKNRATPETLNLLLTLAQEAKLDAKIKAMFAGDIINTTEKRAVLHTALRSTAEQTIIAEGQDIVPEVQQTLNKMQQFVTSVTSGQWKGFTGKTITDIVSIGIGGSFLGPKIVSQALRPYWMTGLNCHFVANVDGTSISEKLKLLDPETTLFIMSSKSFGTQETLTNTLTAKAWFLAKGGSQSDVAKHFVAVTSNVAKATDFGIDADNIFPMWDWVGGRYSLWSAIGLPIALLIGMDNFRSLLKGAHQMDTHFANAPLAENMPVIMGLFSLWYGNFFNAQSHVVLTYDHYLRGLPAYFQQLDMESNGKSVTLNGTHVDYSTGPVIWGGEGTNGQHAYHQLLHQGTALIPADFIMPLQSHNPIGEHHDQLASNCFGQTQALMQGRTLDEALAELSKSNLSDEEKLLIAKHKVMPGNKPSNTLLMDKLTPETLGALIALYEHRTFVQGAIWDINSFDQWGVELGKSLGNDVLARIGAEQDATALDASSNGLINLYRQGKI
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VE4_PCPV1
Sequence: MTAKLYVLLHLYLVLCKKYPLLGLLHTPQPPLHRPPAQCHPSPQKIVCKRRPINDFEDPPTVLENSKTPLTLCVPRTVEPWTVKTTSTITITTTTTSNGTTVTVVVHL
What are the official names of this protein?
Probable protein E4.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E4 protein family.
Protein: MAR3_LEIMA
Sequence: EAEEAARLQAEAEEAARQQAEAEEAARLQAEAEEAARLQAEAEEAARLQAEAE
What are the official names of this protein?
Membrane antigen containing repeating peptides, Clone 39.
What are the subcellular locations of this protein?
Membrane.
Protein: Y4YN_SINFN
Sequence: MYLSPAEIQILLHAAIELVAAAGLGAARALGIMLILPVFTRSQIGGLIRGCLAIAFGLPCLAHVSDGLQAPDPETSLIQIPLLGLKEVFVGVLLGTFLGIPLWGLQAAGEFIDNQRGITSPSTQADPATNSQASAMGVFLGITAITIFVAAGGVEAVLSALYGSYSIWPVYRFQPTLSTQGAVELFGLLDHIMRTTLLVSGPVVFFLGLIDISMMMLRRFAPQFKSGQLSPPIKNIVFPIIMVTYATYLLEGIKLEITQADGTLGWLDKLLK
What is the function of this protein?
Could be involved in the secretion of an unknown factor.
What are the official names of this protein?
Probable translocation protein y4yN.
What is the protein family that this protein belongs to?
Belongs to the FliR/MopE/SpaR family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y2708_BACCR
Sequence: MNDLRYPIGQFTYKRPITEEMIDTWIQEIEDLPNELTKAIKDLDQKQLDTPYRVGGWTVRQVVHHVVDSHMNSYIRFKLALTEKNPTIKPYKEEKWAELPDSKLPVDVSLVMLDSLHKRWVNLLYSLEIEDLEKTFNHPETGETKLAVAIGLYAWHGRHHTAHITSLRKRLNW
What is the function of this protein?
Possible metal-dependent hydrolase.
What are the official names of this protein?
Putative metal-dependent hydrolase BC_2708.
What is the protein family that this protein belongs to?
Belongs to the metal hydrolase YfiT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HAMA_BACCE
Sequence: MTIQDDMVGKHPIENDFWKWLQHEDTESSDLKRHRYLEVDSSNRDEAIKSVAAWLIKYHLSEGKKRVIRKKQEILEKHDFAEYAQSLHVFPKSDKTQKGNLGEIFLSEYLSQTSGVQILVYKLHYNPNIDQSMKGDDVLLVNPDKVLLGESKFRSTPNKRAVEEASELMKDKLTLPMSLGFIADRLFEQGKDELGEVIFDLQFKMSSIEIDIKNIGFLLSTKKVRSIVENNLSSPNSDFIFISLGMDDPAAFLKSVFDYAESNLLEGSYET
What is the function of this protein?
Component of antiviral defense system Hachiman, composed of HamA and HamB.  Expression of Hachiman in B. subtilis (strain BEST7003) confers resistance to phages phi105, phi29, phi3T, rho14, SBSphiJ, SpBeta and SPR.
What are the official names of this protein?
Hachiman protein HamA.
Protein: ZEAYB_MAIZE
Sequence: MATKILALLALLALFVSATNAFIIPQCSLAPSAIIPQFLRPVTSMGFEHLAVQAYKLQQALAASVLQQPINQLQQQSLAHLTIQTIATQQQQQFLPALSQLDVVNPVAYLQQQVLASNPLALANVAAYQQQQQLQQFLPALSQLAMVNPAAYLQQQQLLSSSPLVVGNAPTYLQQQLLQQIVPALTQLAVANPAAYLQQLLPFNQLTVSNSAAYLQQRQQLLNPLAVPNPLVTAFLQQQQLLPYSQFSLMNPALSWQQPIVGGAIF
What is the function of this protein?
Zeins are major seed storage proteins.
What are the official names of this protein?
22 kDa alpha-zein 8, Zein-alpha 22C2.
What is the protein family that this protein belongs to?
Belongs to the zein family.
Protein: COMD5_HUMAN
Sequence: MSAVGAATPYLHHPGDSHSGRVSFLGAQLPPEVAAMARLLGDLDRSTFRKLLKFVVSSLQGEDCREAVQRLGVSANLPEEQLGALLAGMHTLLQQALRLPPTSLKPDTFRDQLQELCIPQDLVGDLASVVFGSQRPLLDSVAQQQGAWLPHVADFRWRVDVAISTSALARSLQPSVLMQLKLSDGSAYRFEVPTAKFQELRYSVALVLKEMADLEKRCERRLQD
What is the function of this protein?
May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237).  Negatively regulates cell proliferation.  Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway.  Involved in kidney proximal tubule morphogenesis (By similarity).  Down-regulates activation of NF-kappa-B (PubMed:15799966).
What are the official names of this protein?
COMM domain-containing protein 5, Hypertension-related calcium-regulated gene protein, HCaRG.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CDK4_MOUSE
Sequence: MAATRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGAAGGGLPVSTVREVALLRRLEAFEHPNVVRLMDVCATSRTDRDIKVTLVFEHIDQDLRTYLDKAPPPGLPVETIKDLMRQFLSGLDFLHANCIVHRDLKPENILVTSNGTVKLADFGLARIYSYQMALTPVVVTLWYRAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPREVSLPRGAFAPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKEESDAE
What is the function of this protein?
Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the cell-cycle during G(1)/S transition.  Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complexes and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase.  Hypophosphorylates RB1 in early G(1) phase.  Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals.  Also phosphorylates SMAD3 in a cell-cycle-dependent manner and represses its transcriptional activity.  Component of the ternary complex, cyclin D/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex (By similarity).
What are the official names of this protein?
Cyclin-dependent kinase 4, CRK3, Cell division protein kinase 4, PSK-J3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus membrane. Note=Cytoplasmic when non-complexed. Forms a cyclin D-CDK4 complex in the cytoplasm as cells progress through G(1) phase. The complex accumulates on the nuclear membrane and enters the nucleus on transition from G(1) to S phase. Also present in nucleoli and heterochromatin lumps. Colocalizes with RB1 after release into the nucleus (By similarity).