PharMolix/UniProtQA huggingface dataset:
Protein: DZIP1_DANRE
Sequence: MPFYDNVYYPYPSDPPGTHSSAGIPSLLSSPQSQPSSGSQSRPAPSTMSGPLTSSGASTSIPPPFKFRSRRENVDWRRINAVDVDRVACEMDFQALQEHINAVTFCSVEGERCHRCQSPVDPALIKLFRLAQLTVEYLLHSQDCLSISLQAAEERLLAEAREREQICVQLQKKTQDAKALKEELKQRKKIIASQQAMFSAGISANYHKCQHCEKAFMNASFLQSHMQRRHPSEFDMKLMTDNQKKIQTVKLQDEINKLQEQLTLVTSQMETQQKDYTAKQEKELIQRQEEFKRQLEIWKEEEKMRMNSKIDEVKQACQRDMDSINQRNRNLETELLKLQQKNIQESMQSVQTQPNASTSNEHWQEVVKLQQKLHKQEVKWTGKMQKMKEDHDREKSLLQEELCKVSSAVSEGMEESRRQVQELSHRLQEQQQIITSQNKQMKQISSKPPTITVQREGVSTPSPETKAKVVVSEQSNSVHKLDPIVELSEEDKDSSSISESPTENRSWQKEVQELLKNPGLRRDMRLAAQHNLDDRLQSLGIKGVSGLSKNLYKSSMTQIISDRRKKLEEDPVYRRALKEISHKLEQRVKERNTEQPVKSKLHEQVVQSRPRSSSFPSTVTRVMSGPASKQQRTPQPVPRSRTNVPHKTSTPLQHRRTPPFSSDEDSSEEEEEEEEEEESSDEESPQMQKKTVLVNSSTAKAQNTAKTQSTAQSVRSAVALTSAEPTNVTTLSDSDWTDGSEMEEINLSQLHKHTDQNGNLKNVTHSNVKALGKSLEKQLAARGPKKPAGGVNTFLEKPTDVRNTRQNAKKELKYSDDDDDDDDDWDISSLEDVPAVAKPTQCPVPVRKSLDKSQDTSTSVWGSSTGKGHKPGLTDAGTASTLKSSLVTVSDWDDSDEI
What is the function of this protein?
Molecular adapter that recruits protein complexes required for cilium assembly and function to the cilium basal body (PubMed:19852954).  Required for establishment of left-right asymmetry during embryogenesis (PubMed:19852954).  Acts as a permissive factor that is required for the proper regulation of Hedgehog (Hh) target genes in response to Hh signals (PubMed:15115751).  Acts downstream of the Smoothened protein to modulate Gli activity in the somites of the developing embryo (PubMed:15198976).
What are the official names of this protein?
Cilium assembly protein DZIP1, DAZ-interacting protein 1 homolog, DAZ-interacting zinc finger protein 1, Iguana protein.
What is the protein family that this protein belongs to?
Belongs to the DZIP C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Nucleus. Cytoplasm. Note=In the cytoplasm, it is localized in large vesicles. These vesicles correspond to lysosomes and/or endosomes. Can shuttle between the cytoplasm and the nucleus in a manner correlated with Hh activity.
Protein: RL6_CLOD6
Sequence: MSRIGVKPIIIPAGVEVTIAEGNLVTVKGPKGTLTKQLSAELNIKKEENTIMVERPTDNKKHRSLHGLTRTLLDNMVVGVNTGFEKKLELKGVGYRAQKQGKKLVMNLGFSHPVEMEDPEGITVEAPNQTELIVKGIDKQLVGNYAAKIRAWRKPEPYKGKGIKYVDEVIRRKEGKTGKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RH27_ORYSJ
Sequence: MAPAPATTSSSKRSKKRKQPVAPPPESDSESEELSYDTAAADEEEGEEEAPNQMEELEEEQEEEKKEKKQKKEMSKEKKRKKEKGNEGGSGILTNMLFSELGVSEPTARAIREMNYTYLTQIQARSIPHLLNGKDVMGAAKTGSGKTLAFLIPAIEMLHHAHFMPRNGTGVVVVCPTRELAIQTHNVAKELMKYHSQTLGYIIGGNGRRGEADQLAKGVNLLVATPGRLLDHLQNTKGFIYRRLKCLIIDEADRLLEQNFEEDMKQIFKRLPLNRQTVLFSATQTEQVKEFAKLSFEKNEESTSKPVYVGVDDAETNATVEGLQQGYCVIDSARRFLVLYAFLKKKQNKKVMVFFSSCNSVKFHAELLNFLQIECSDIHGKQKQQKRTTTFFNFCKAEKGILLCTNVAARGLDIPDVDFIVQYDPPDEPKDYIHRVGRTARGEKGKGEALLFLLPQELKFLIYLKAAKISLTELVFNENKVPNLQSHLENIVGENYFLNQSAKEAYRSYILAYDSHSMKDIFDVHNLNLKDVAASFCFKNPPKVNIDLESSASKHRRKMRKVDGGRRHGISAANPYGRKGGDDKRQFARF
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase 27.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.
Protein: YH131_YEAST
Sequence: MVSKHIELLLLLEVMRTSSIEHVDEDEGDFNLSILLFAMDNLPSIGRAILNKRTTCMHDVGSKIYCGPKKQRFLLCWSTKL
What are the official names of this protein?
Putative uncharacterized protein YHR131W-A.
Protein: NADD_CLOP1
Sequence: MKKIGVFGGTFDPIHIGHIYIAYEAYKILELDEVIFMPAGNPPHKKWKDITDEIIRYEMVKKAIEPYSFFSINNYEIEKKGLSFTYETLRYLHESFKEVELYFITGADCLINLNSWKNINEIFKFSNLVVFNRPGFDKNDLLKRKEEFDREYCTNIVYLDLLNIEISSTLIRERVHDSLEVKFFLPPGVVDIIDKYNLYRRE
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: KAPCA_MOUSE
Sequence: MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF
What is the function of this protein?
Phosphorylates and activates ABL1 in sperm flagellum to promote spermatozoa capacitation.
What are the official names of this protein?
cAMP-dependent protein kinase catalytic subunit alpha, PKA C-alpha.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Nucleus. Mitochondrion. Membrane; Lipid-anchor. Note=Translocates into the nucleus (monomeric catalytic subunit) (By similarity). The inactive holoenzyme is found in the cytoplasm. Distributed throughout the cytoplasm in meiotically incompetent oocytes. Associated to mitochondrion as meiotic competence is acquired. Aggregates around the germinal vesicles (GV) at the immature GV stage oocytes. Colocalizes with HSF1 in nuclear stress bodies (nSBs) upon heat shock (By similarity). SUBCELLULAR LOCATION: [Isoform 2]: Cell projection, cilium, flagellum. Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Expressed in the midpiece region of the sperm flagellum (By similarity). Colocalizes with MROH2B and TCP11 on the acrosome and tail regions in round spermatids and spermatozoa regardless of the capacitation status of the sperm (PubMed:27105888).
Protein: ISPE_CHLPB
Sequence: MQHISVKAFAKINLGLLITGKRQDGYHTLETVFSPINWYDELTFSAADGLGMSCSTIDLPADDSNLCLKAAKALREYAGIDKGVAITLTKRIPFGAGLGGGSSDAATTLRVLNALWELDVPQGDLHGIATGLGADVPYFLETKGLAYATGIGEILEDLEASLPFHIVTVFPGEHISTVWAYRNFYPRFVRQAPDLKQMMKDLCLRSDFSVLPALENDFEPAVFDHYPAVRKVKEQLLEKGGFYASLSGSGSAVFGLFEELRDAENAARFFREHFPVALTEPFFTMQ
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: RLMH_SALNS
Sequence: MKLQLVAVGTKMPDWVQTGFTEYLRRFPKDMPFELIEIPAGKRGKNADIKRILDKEGEQMLAAAGKNRIVTLDIPGKPWDTPQLANELERWKQDGRDVSLLIGGPEGLSPACKAAAEQSWSLSALTLPHPLVRVLVAESLYRAWSITTNHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDM12_PARBD
Sequence: MSIDIDWERATSGPDGELLAERIRSFIHDKFQQMVLPRFIRSVQVTSFNFGTIPPELEIRDLTDPFPDFYEDGDEDLSVSSEEQSPMREQADRYRERIDSWQANSPGGLEVQMSGRMGFGHPLQLAPDEDGSRLHPLRSPINLGDINPYLFPRSGTPGIPGGTSNLGYFMPLSGLSGSQTPLRAVTRGNPFSGGWPDSPLENESRIGHGQGPPRRRSEVNVDAIQSRPSTANTGNTLFSRGSVSTGDPRHSHSSQTVLANNPGQAPEANDSPVSAVPPLSGTPPRRMREQKAEDFQVFCRTKYAGNISLSLTAEILLDYPMPSFVGLPLKLNITGLTFDAVAVLAYIRRRIHFCFLSPEDAYALIGPETGGGGGDTMEPNSLRRKNLSLLRKIRVESEIGRKENGKQALKNVGKVEKFVLEQVRRIFEEEFVYPSFWTFLV
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.  The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 12, Mitochondrial inheritance component MDM12.
What is the protein family that this protein belongs to?
Belongs to the MDM12 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: Y3178_CROS8
Sequence: MYDNLKSLGITNPDEIDRYSLRQEANNDILKIYFHKDKGEFFAKSVKFKYPRQRKTVVADGVGQGYKEVQEISPNLRYVIDELDQLCQRDRTEVDLKRKILDDLRHLESVVANKISEIESDLEKLTRNK
What are the official names of this protein?
UPF0325 protein ESA_03178.
What is the protein family that this protein belongs to?
Belongs to the UPF0325 family.
Protein: FPG_YERPP
Sequence: MPELPEVETSRRGIEPYLVGQTILYAVVRNARLRWPVSDEILTLSDQPVLSVQRRAKYLLLELPKGWIIIHLGMSGSLRVLSEETAAEKHDHVDLVVSNGKILRYTDPRRFGAWLWAKDLETSNVLAHLGPEPLSDEFTAQYLFDKSRNKRTLIKPWLMDNKVVVGVGNIYASESLFAAGILPDRAAGSLTDAESVLLVATIKAVLLHSIEQGGTTLRDFLQSDGKPGYFAQELQVYGRAGEPCRQCGHPIEIAKHGQRSTFFCRHCQFRPIWPIMLW
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: TBA5_CHICK
Sequence: MRECISVHVGQAGVQMGNTCWELYCLEHGIQPDGQMPSDKTIGGGDDSFTTFFCETGAGKHVPRAIFVDLEPTVIDEVRAGIYRQLFHPEQLITGKEDGANNYARGHYTIGKEIIDQVLDRIRKLADQCTGLQGFLCFHSFGGGTGSGFTSLLMERLSGDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNSCFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVAGGDLAKVQRIVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDIAALEKDYEEVGLDSYEDEEEGEE
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin alpha-5 chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: IF2_MARN8
Sequence: MAEVTVKQLAADVGAPVDRLLKQIVEAGLKARSENDAVTSDEKQQLLAYLRKNHGEAEAEPRKITLKRKTTTTLKAGKAKTVNVEVRKRRTYIKRAELQPEPEAEAPAPEEPVQAPAAEQAPVEEAPKVAAEAAPAEAPETEAPAAAETEAKAAPEPAAESAEPAIAPEDIPMPPPEDEGRDRKPKKKKEKVRERGDDIEEGKPKKKQAGHRGPRSRPVEEPVVLSEDEEETTLRKPLRAKKKPKEKRHAFERPTKPMVREVQIPETITVGDLAQRMAVKSADVIKTLMGMGVMATINQALDQETAILVTEELGHKPKAVSEDAFEEEVLSEITGPDEGKEKIKRAPVVSVMGHVDHGKTSLLDHIRRAKVAAGESGGITQHIGAYHVETEHGMVSFLDTPGHAAFTAMRARGAQCTDIVILVVAADDGVMPQTKEAVEHARSAGVPIVVAINKMDKEEADPDRIKNELSALEVIPEDWGGDVQFVPVSAHTGMGIDDLLEAVLLQAEILELEASPDAAAKGVVVESSLERGRGSVATVLVQNGTLRQGDMVVAGSFFGKVRAMTDEAGRQVKEAGPSIPVEILGLNGTPDAGDEFFAVADEKKAKELAEFRQTREREQRLQRQQAAKLENMFENMGKDEVKTLNVVLKTDVRGSLEAITKALQDLGNDEVQVKIVSSGVGGIAETDVSLAMATNAVIFGFNVRADTASKRLVEQEGLDLRYYSIIYNLIDDVKAALTGMLKPEFREDIVGIADVRDVFRSPKFGQVAGCMVTEGTVYRNKPIRVLRDNVVIFEGELESLRRFKDDVAEVRNGMECGIGVKGYDVKVGDQIEVFDRVRVERQLESTGA
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSZ_RICPR
Sequence: MVLNIKAPENIVLKPTITVFGVGGAGSNAVNNMIHANLQGANFVVANTDAQSLEHSLCINKIQLGVSTTRGLGAGASPEVGALAAQESENEIRSSLENSNMVFITAGMGGGTGTGSAPIIARIAKELGILTVGVVTKPFHFEGGHRMKTADKGLIELQQFVDTLIVIPNQNLFRIANEQTTFADAFKMADDVLHAGVRGVTDLMIMPGLINLDFADIKAVMSEMGKAMMGTGEDSGEDRAIKAAESAISNPLLDHSSMCGARGVLINITGGPDMTLFEVDNAANRIREEVDNIDANIIFGSTFNPELKGIIRVSVVATGIDADKVPKYKLAIDKNTNTLPEETYNESIIQHTQIETIPSFNSYSTENIEINESSIKQDYTGNEQELRLHVNAVNKPENNSQKSSFLGKIWESLRTSNNQTLERKNVIVNTVDQDNKESDIHDIPAFLRKKRD
What is the function of this protein?
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site.  The regulation of the ring assembly controls the timing and the location of cell division.  One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells.  Binds GTP and shows GTPase activity.
What are the official names of this protein?
Cell division protein FtsZ.
What is the protein family that this protein belongs to?
Belongs to the FtsZ family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane.
Protein: ATG27_ARTBC
Sequence: MARYKGLSILSLFAVFSSLASAELDCSNIKVDGVMWNFGKLGGAHSISETASSHEGYNTTYTLDICKPLTKTLCKKGAFVCAVRNATDINGIERTMDVIDIAGNFVLNSGRTLDPIFTRLKKEDPKTEGLKMELHGGKHKFGNLLKRQKAVITLLCDRERTGLEGLESPKPDGDKKKDGEKKDDDKKDNKDKEGKSKRDGEENKRSLIFKSYNEEEGTLDLEWKTKYACENVEDGGSAPSGHWGFFTWVIVLYVVLVSLPLLSERVTNVRCHSQPVPVHFGLSDIRLVAQLQPVWSSRVGLASSQ
What is the function of this protein?
Effector of phosphatidylinositol 3-phosphate kinase signaling (By similarity).  Regulates the cytoplasm to vacuole transport (Cvt) vesicle formation.  Plays a role in ATG protein retrieval from the pre-autophagosomal structure (PAS) (By similarity).
What are the official names of this protein?
Autophagy-related protein 27.
What is the protein family that this protein belongs to?
Belongs to the ATG27 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Mitochondrion membrane; Single-pass membrane protein. Preautophagosomal structure membrane; Single-pass type I membrane protein. Note=Cycles among the pre-autophagosomal structure (PAS), mitochondria and Golgi.
Protein: PUR2_LISMO
Sequence: MNLLVVGSGGREHAISKKLLASNNVEKVFCAPGNDGMRLDDIQLVAISETDKAGLIDFAKKAEIAFVIVGPEVPLLEGVVDALEEAGIKAFGPKANAALIEGSKDFAKQFMEKYAIPTAASRTFTDYAEAKAYLNERGVPIVIKADGLAAGKGVTVALEMEEAVLALKDMMLEEKFGDASLKVVIEDFLAGEEFSLMAFVNGEEVYPMSIAQDHKRAYEGDKGPNTGGMGAYSPVPHISEAVIEEAVQKILLPTAKGMVKEGRYFRGILYAGLILTADGPKVIEFNARFGDPETQVVLPRLESDFAALIDALLHNEKPDVRFKKTGLTLGVVLASAGYPEHYEKGNKLTGLNDIAEDVAIYHAGTKQDENGDFISDGGRVLLLAKEAETMSDARTLLYPEMQKLDNPNFFYRIDIGTKAE
What are the official names of this protein?
Phosphoribosylamine--glycine ligase, GARS, Glycinamide ribonucleotide synthetase, Phosphoribosylglycinamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the GARS family.
Protein: GUC2E_MOUSE
Sequence: MSAWLLPAGGLPGAGFCVPARQSPSSFSRVLRWPRPGLPGLLLLLLLPSPSALSAVFKVGVLGPWACDPIFARARPDLAARLAANRLNRDFALDGGPRFEVALLPEPCLTPGSLGAVSSALSRVSGLVGPVNPAACRPAELLAQEAGVALVPWGCPGTRAAGTTAPAVTPAADALYVLLRAFRWARVALITAPQDLWVEAGRALSTALRARGLPVALVTSMETSDRSGAREALGRIRDGPRVRVVIMVMHSVLLGGEEQRYLLEAAEELALTDGSLVFLPFDTLHYALSPGPEALAAFVNSSQLRRAHDAVLTLTRRCPPGGSVQDSLRRAQEHQELPLDLNLKQVSPLFGTIYDAVFLLAGGVKRARTAVGGGWVSGASVARQVREAQVSGFCGVLGRTEEPSFVLLDTDASGEQLFATHLLDPVLGSLRSAGTPMHFPRGGPAPGPDPSCWFDPDVICNGGVEPGLVFVGFLLVIGMGLTGAFLAHYLRHRLLHMQMASGPNKIILTLEDVTFLHPPGGSSRKVVQGSRSSLATRSASDIRSVPSQPQESTNVGLYEGDWVWLKKFPGEHHMAIRPATKTAFSKLRELRHENVALYLGLFLAGTADSPATPGEGILAVVSEHCARGSLHDLLAQREIKLDWMFKSSLLLDLIKGMRYLHHRGVAHGRLKSRNCVVDGRFVLKVTDHGHGRLLEAQRVLPEPPSAEDQLWTAPELLRDPSLERRGTLAGDVFSLAIIMQEVVCRSTPYAMLELTPEEVIQRVRSPPPLCRPLVSMDQAPMECIQLMTQCWAEHPELRPSMDLTFDLFKSINKGRKTNIIDSMLRMLEQYSSNLEDLIRERTEELEQEKQKTDRLLTQMLPPSVAEALKMGTSVEPEYFEEVTLYFSDIVGFTTISAMSEPIEVVDLLNDLYTLFDAIIGAHDVYKVETIGDAYMVASGLPQRNGQRHAAEIANMSLDILSAVGSFRMRHMPEVPVRIRIGLHSGPCVAGVVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVNMSTVRILRALDQGFQMECRGRTELKGKGIEDTYWLVGRLGFNKPIPKPPDLQPGASNHGISLQEIPPERRKKLEKARPGQFTGK
What is the function of this protein?
Catalyzes the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors.  Plays an essential role in phototransduction, by mediating cGMP replenishment (PubMed:21598940).  May also participate in the trafficking of membrane-asociated proteins to the photoreceptor outer segment membrane (PubMed:17255100).
What are the official names of this protein?
Retinal guanylyl cyclase 1, Guanylate cyclase 2E, Guanylyl cyclase GC-E.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Photoreceptor outer segment membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: Y1074_BACCZ
Sequence: MLYLHDVWVNWFEGEENGYNVCHFYEWRKDDTIELLDQVPLLKVDSTLYHYIENELLELPQKLLEDVHHKAYIRKNHERLQQEYCFVVTDGKGIIAIDTIGYNVPIRKSRLIPRQEQMVYEMVENVQAEKYEFQVEEMEKEHHILSPSPFVMNGLTRKERQLKQLLFMALDQLHTTKNTAEIRYWFTEWDPSAYGMVQHMEFEDIWAKLYDEAKAGWSEKHEQLCERLVKGQPFFEKLWEMENEQKVN
What are the official names of this protein?
UPF0736 protein BCE33L1074.
What is the protein family that this protein belongs to?
Belongs to the UPF0736 family.
Protein: RL34_CLOBL
Sequence: MFMTYQPKKRQRKKEHGFRKRMKTSSGRNILRKRRQKGRKRLTA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: RL10A_RAT
Sequence: MSSKVSRDTLYEAVREVLHGNQRKRRKFLETVELQISLKNYDPQKDKRFSGTVRLKSTPRPKFSVCVLGDQQHCDEAKAVDIPHMDIEALKKLNKNKKLVKKLAKKYDAFLASESLIKQIPRILGPGLNKAGKFPSLLTHNENMVAKVDEVKSTIKFQMKKVLCLAVAVGHVKMTDDELVYNIHLAVNFLVSLLKKNWQNVRALYIKSTMGKPQRLY
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L10a.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FINO_ECOLI
Sequence: MTEQKRPVLTLKRKTEGETLVRSRKTIINVTTPPKWKVKKQKLAEKAAREAELAAKKAQARQALSIYLNLPTLDDAVNTLKPWWPGLFDGDTPRLLACGIRDVLLEDVAQRNIPLSHKKLRRALKAITRSESYLCAMKAGACRYDTEGYVTEHISQEEEAYAAERLDKIRRQNRIKAELQAVLDEK
What is the function of this protein?
One of the components on the FinOP fertility inhibition complex, which inhibits the expression of traJ gene, which in turn regulates the expression of some 20 transfer genes.  The transfer genes are responsible for the process, called conjugal transfer, in which DNA is transmitted from one bacterial host to another.  RNA-binding that interacts with the traJ mRNA and its antisense RNA, finP, stabilizing finP against endonucleolytic degradation and facilitating sense-antisense RNA recognition.
What are the official names of this protein?
Fertility inhibition protein, Conjugal transfer repressor.
What is the protein family that this protein belongs to?
Belongs to the FinO family.
Protein: BIOD1_ECO57
Sequence: MSKRYFVTGTDTEVGKTVASCALLQAAKAAGYRTAGYKPVASGSEKTPEGLRNSDALALQRNSSLQLDYATVNPYTFAEPTSPHIISAQEGRSIESSVMSSGLRALEQQADWVLVEGAGGWFTPLSDTFTFADWVTQEQLPVILVVGVKLGCINHAMLTAQAIQHAGLTLAGWVANDVTPPGKRHAEYMTTLTRMIPAPLLGESPWLAENPENAATGKYINLALL
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD 1, DTB synthetase 1, DTBS 1, Dethiobiotin synthase 1.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASNA_STRR6
Sequence: MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGMQDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPDEDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESILPKQITFIHTEELVERYPDLTSKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDYDDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLELEWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RM10_SCHPO
Sequence: MFNILSRVCRSSSFHGFLRSSGYPRFGASFRGISMLNDLNNSANYQSKKRVGRGPASGLGKTSGRGHKGSGQRRGRRIKPGFEGGQTPITKLFPKVGHSTGHLKKPLRLGLGRVQEWIDRGRLDASKTITMKDLLDSRCCRGIKHGVELTADEPGLLKTAISIEVSKATVQAIQQIKNAGGSITTVYFSPLALRAHLHPSSFRTPPRPPLPVSKKDIRYYTNPHFAGYLANVKNIRELYYGDQRFPYEPIVKDK
What are the official names of this protein?
54S ribosomal protein L10, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MUTS_LACAC
Sequence: MMEQYYEIKKQYPDAFLFYRVGDFYELFEEDAVKGAQILELTLTHRSNKTKNPIPMAGVPHMAVDTYVNTLVEKGYKVALCEQLEDPKKAKGMVKRGIIQLVTPGTMMSEGPNDAKDSNYLTSVVTTEKGFGVAYSDLSTGEVYATHLKSFEAVSNELLSLRTREVVYNGPLTEQNKEFMHKANITVSSPTPIEGEHAEISYVGQNLTNSAEKKATEQLVGYLLSTQKRSLAHLQVAKSYEVNQYLQMSHTVQNNLELVASAKTGKKMGSLFWVLDKTHTAMGGRLLKQWLARPLLNVDEINHREEMVQALFDGYFTRENAIDALKGVYDLERLTGRIAFGNVNARELLQLSRSLEAVPTILDALDQSDSDVLKEFAQKIDPLKGVAELITTTIVKDPPLLTTEGGLIREGVDKQLDRYRDAMNNGKKWLAQMEADERQKTGIENLKVGYNKVFGYYIQVSNGNKNKVPLDRYTRKQTLTNAERYITPELKEHENLILEAQTRSTDLEYDLFVRLREEVKKYIPALQKLGSQLAALDVFCGFASVAEQNNYCRPSFHTDNQDIDVVNGRHPVVEKVMTAGSYIPNSVEMDSSTNIYLITGPNMSGKSTYMRQMALIAIMAQVGSFVPADSADLPIFDQIFTRIGAADDLISGQSTFMVEMSEANDALQYATKRSLVLFDEIGRGTATYDGMALAGAIVKYLHDKVGAKAFFATHYHELTDLDETLDHLKNIHVGATEENGKLIFLHKILPGPADQSYGIHVAQLAGLPKSVLREATKLLKRLEAQGSEIAPASQQLDLFAQPEVNDSEEVQAEQAVITDTEQNILDDISNLYLADKTPLQIMQLVADWQKDLKDDK
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.