PharMolix/UniProtQA huggingface dataset:
Protein: HEMA_BRV2
Sequence: MLSLILFFPSFAFAATPVTPYYGPGHITFDWCGFGDSRSDCTNPQSPMSLDIPQQLCPKFSSKSSSSMFLSLHWNNHSSFVSYDYFNCGVEKVFYEGVNFSPRKQYSCWDEGVDGWIELKTRFYTKLYQMATTSRCIKLIQLQAPSSLPTLQAGVCRTNKQLPDNPRLALLSDTVPTSVQFVLPGSSGTTICTKHLVPFCYLNHGCFTTGGSCLPFGVSYVSDSFYYGYYDATPQIGSTESHDYVCDYLFMEPGTYNASTVGKFLVYPTKSYCMDTMNITVPVQAVQSIWSEQYASDDAIGQACKAPYCIFYNKTTPYTVTNGSDANHGDDEVRMMMQGLLRNSSCISPQGSTPLALYSTEMIYEPNYGSCPQFYKLFDTSGNENIDVISSSYFVATWVLLVVVVILIFVIISFFC
What is the function of this protein?
Structural protein that makes short spikes at the surface of the virus.  Contains receptor binding and receptor-destroying activities.  Mediates de-O-acetylation of N-acetyl-9-di-O-acetylneuraminic acid, which is probably the receptor determinant recognized by the virus on the surface of erythrocytes and susceptible cells.  Also hydrolyzes 5-N-acetyl-4-O-acetylneuraminic acid and N-acetyl-9-O-acetylneuraminic acid, but displays a substrate preference for N-acetyl-9-di-O-acetylneuraminic acid.  This receptor-destroying activity is important for virus release as it probably helps preventing self-aggregation and ensures the efficient spread of the progeny virus from cell to cell.  May serve as a secondary viral attachment protein for initiating infection, the spike protein being the major one.  Seems to be a 'luxury' protein that is not absolutely necessary for virus infection in culture.  However, its presence in the virus may alter its pathogenicity.  May become a target for both the humoral and the cellular branches of the immune system.
What are the official names of this protein?
Hemagglutinin-esterase, HE protein, E3 glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the influenza type C/coronaviruses hemagglutinin-esterase family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Note=In infected cells becomes incorporated into the envelope of virions during virus assembly at the endoplasmic reticulum and cis Golgi. However, some may escape incorporation into virions and subsequently migrate to the cell surface (By similarity).
Protein: BRI3_MOUSE
Sequence: MDHKPLLQERPPAYNLEAGQGDYACGPHGYGAIPTAPPPPPYPYLVTGIPTSHPRVYNIHSRTVTRYPANSIVVVGGCPVCRVGVLEYCFTCLGIFLAIVLFPFGFLCCFALRKRRCPNCGAVFT
What is the function of this protein?
Participates in tumor necrosis factor-alpha (TNF)-induced cell death (Ref. 4).  May be a target of Wnt/beta-catenin signaling in the liver (By similarity).
What are the official names of this protein?
Brain protein I3.
What is the protein family that this protein belongs to?
Belongs to the BRI3 family.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein. Cytoplasm, perinuclear region. Note=Co-localizes with MGAT1 and IFITM3 at the perinuclear region.
Protein: PYRB_PAEAT
Sequence: MKHLLSTENLSLFDAVRVLDTAEEMSAVGEREVKKLPALRGRTVVNLFFEDSTRTRISFEAAAKRLSADVINFAAKGSSVSKGESLKDTAQTLAAMGADAVVIRHWASGAPHRLAATDWIDAAVINAGDGTHEHPTQALLDAFTMRRHWSQVNGTESTGADLKGMRVAIAGDVLHSRVARSNVWLLKTLGAEVTLVAPPTLLPIGVEHWPCKVSYNLDETLEAGIDAMMMLRVQGERMNASFFPSTREYSRRWGFDDARLRMLDDLGMKDTIIMHPGPMNRGLEISSAAADSPRSTVLAQVRNGVSVRMAALYLLLSGDSREAAPNVSQSSKETN
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: RECF_FRATO
Sequence: MYISNLRLQNFRNIPAKSFDFKNSINFIVGKNGSGKTSILESIYFLSHSRSFRSSQLNRIINHNADEFIIYTKAYNPDEITISLSRKKNSNNISKLNLEIQKNHTEITRNLPIQLINPESFNIINSGAQQRCKVIDWGAFYLDKTFLKIWQQTKFLVKQRNSALKQNYPYSYILSIDKKLCEFAEILDYKRQAYFTKLKPKIYEILSHFNPNLQLDIDYFRGWNLHKSLAQVLEESFNYDNKYKVTNHGPHKADIVLSVSHKPIQDIFSRGQQKLLICALKLAQGEIHNSENDNKCIYLIDDITSELDSIHTLTLFNYLKQLKSQVFITTTEKNKINEFIDTNSYILEI
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCUR1_XENTR
Sequence: MSRLQLRFLLRRALSGSGCPRYSMPGSGCPGCFLPRVTCFRDFNIITSTMQYNLDKRNIYTSVGKHYFFDTHAVVQLLEANGFSAEQSEIVVSALVKILNVNMNLIHKDMVTKEQQEISLQQVMSLIASVKKDMIILEKSEFSALRTQNEKVKIELQQLKKQLNDSIVKVRASNKLDFNLEKSRVKEMHADNERKLLELRTSIVELHSQQDRGLTQTKRKIDTEVSGVKTMQESHKLDTIKYLAGSVFTCLTIALGFYRLWI
What is the function of this protein?
Key regulator of mitochondrial calcium uniporter (mcu) required for calcium entry into mitochondrion.
What are the official names of this protein?
Mitochondrial calcium uniporter regulator 1, MCU regulator 1, Coiled-coil domain-containing protein 90A, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the CCDC90 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: FLGI_AGRVS
Sequence: MSIRVLLFSIFTGFLLAAAGPALAQGSRIKDVASLQAGRDNQLIGYGLVVGLQSTGDSLRSSPFTDQSMRAMLQNLGISTQGGQSSAKNVAAVMVTATLPPFGSPGSRIDATVSSLGDATSLRGGTLIMTSLSGADGQIYAVAQGSVVVSGFTAQGQAATVTEGVTTSGRVPNGAIIERELPSKFKDSVNLVLQLRNPDFSTSLGMARRINNYATATYGAPIAEARDSQEVVIQKPRTADLAQLMADIENLVVETDTPAKVVINERTGTIVIGADVRVSKVAVSYGTLTVQVNETPQVIQPQPFSSGTTATQPQTDISAQKTGDKVAIVDGPDLRTLVAGLNNIGVKPDGIIAILQGIKSAGALQAELVLQ
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: ATPD_STRPM
Sequence: MTKKEQALIEQYAKSLVEVASEHHSLDALQADVLAILETFVTTNLDQSLSSLAVPHAEKIKLLTLLKGNNSVYMNNFLNLILQNEREAYLYQMLQTVLNEIAIVSNQYDVTVTSSLPLTEEQKSRVRAVVAKKFAVTAGRLIEKVDPSLIGGFIISVNNKVIDTSIRRQLQAFKMNLK
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: YJ018_HUMAN
Sequence: MYNPWQVGASLAPARAGPRPFPTPRARPPDCSGGHAPSGFPALGLRTAQRPRPFSSSPRSASGRLRGPRPVARGPAHSSSPTGLPAYLPPAAALDSQTSAPTVSPVTRPRVVARGKTPRVSLAGLETLSSLLHQQQLFD
What are the official names of this protein?
Putative uncharacterized protein FLJ43185.
Protein: TYPH_YERPY
Sequence: MFLAQEIIRKKRDGQPLSEEEIRFFINGIRDNVVSEGQIAALAMTIYFHDMSMPERVALTMAMRDSGTVLNWKSLNLNGPLVDKHSTGGVGDVTSLMLGPMVAACGGYVPMISGRGLGHTGGTLDKLEAIPGFDIFPDDNAFRKIIQNVGVAIIGQTSSLAPADKRFYATRDITATVDSIPLITASILAKKLAEGLDALVMDVKVGSGAFMPTYSLSADLAQAIVGVANGAGCKTTALLTDMNQVLASSAGNGVEVREAVRFLTGEYRNPRLLEVTMALCVEMLLSGGLAHDEADARAKLQAVLDNGKAAEVFGRMVAAQKGPVDFVERYDSYLPVATLSKPVFAEQTGIITAMDTRALGMAVVALGGGRRRATDPIDYSVGLTEMARLGTRVDGQQPLAVIHANNEDDWQQAAEAVRAAITLGNNAPEETPVIYRRITE
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: ARO1_KOMPG
Sequence: MSGLIEKVSILRNDSIHVGYNMSSHIVDEILTKKASSTYVLITDSNIVKMGHLQTFVDEFNRLIPSKRPGSRILTYVVPPGEANKNRATKAAIEDYLLEKGCTRDTFILAIGGGVIGDMIGYVAATFMRGVRFVQIPTSLLAMVDSSIGGKTAIDTPLGKNFIGAFWQPDYVFVDVAFLETLPEREFINGMAEVVKTAAIWNEQEFSRLETYSKRFLKVIRDRRVDDSVDLTSLKEHIIKLVLESIKVKAEVVTLDEREGGLRNLLNFGHSIGHAIEAILTPQALHGECVSIGAVLEAELSRYLGILSPVAVSRLYKCFAAYGLPVSIADKLVQKRTNGKKCPVDVLLQKMAIDKKNDGSKKKVVLLSKIGKCYEPKASYVNDEDLRFVLTDEVLVKDFNSAPSTAVVVPPGSKSISNRALILAALGKGECKIKNLLHSDDTEHMLNAVAALKGADISFDDNGETVVVTGNGGNFTATDAEIYLGNAGTASRFLTSVASIVKPDSNTTHVILTGNARMQERPIGPLVDALRTNGSDIEYLNREGSLPLKIKSGNGLKGGRIELAATISSQYVSSVLMCAPYASEPVTLSLVGGKPISLLYVDMTIAMMKSFGIEVTKSTTEPYTYHVPQGHYVNPAEYVIESDASSATYPLAFAAMNGTQVTIPNIGSSSLQGDARFAVDVLKPMGCKVEQTATSTTVQGPTKGTLKPLPLVDMEPMTDAFLTASVVAAIANDTNQSTSIVGISNQRVKECNRIEAMITQLAKFGVRAKELEDGIEVFGIDYHHLKTPSDGVYTYDDHRVAMSLSLLAGLAESPVLIQERHCTGKTWPGWWDILHTTFNVELDGHEAVVETTTAKANEDKSIIVIGMRAAGKSTLSHVIAQTLKGFKVVDLDDVFVEKYGDIREFIKENSWELFREKEAMIAKEAFKNYSKNTVISTGGGIVETEASRKLLKQQMKDGHIVLHLHRDIEETVVFLSQDKTRPAYVDEINQVWERRKNLYKECSNYFFFSPHCQTEREFFTLKKTFSKFINRITGGAVPSIPNGRSAFVCLTYEDLAPVSSKLTRVTNGCDAVELRVDLLKQHDSHFISNQIGILRNQTSVPILFTIRTKSQGGRFPDDSYEDIERLLNLAIKLGVEYVDLELSLPESLLDSVASKRQFTKIIGSHHDFSGTVKWNNVEWENKYLLALKLNVDIIKFVGTATSLNDNWELEHFRSLHTDKPFIGINMGPLGKVSRVFNTILTPVTHKDLPSSAAPGQLTLKEINEYFGQFGGSSRKKFYIVGKPISHSKSPELHKTFYDEFGLSHTFDKFETDDAAKVFNDLVKGNDELGGCAVTIPLKIDMLKYVNELTDSAKSIGALNTIIPIGDGRFIGDNTDWIGIRDSLHQAGCEIAPESSVGLVVGGGGTSRAAVYALHQMGCSKIYMLNRTPSKLSEIKNHFPSNYNIHIVDSLDAIDEDDKLDAAVSTVPGDKPLDDQLISLLKKLLEKKRGHAVLLEAAYKPRETPIMALAFSRGWKVVPGSKMLVNQGIEQFYKWTGYQFSSHIDL
What is the function of this protein?
The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.
What are the official names of this protein?
Pentafunctional AROM polypeptide.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the shikimate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS7_BUCA5
Sequence: MKNKILFIDRDGTLIDEPINTFQVDSINKLVFKKYVISSLRKLVELDYKLIMITNQDGLGTESFPLQDFSTAHLFMLSVFRSEGVIFDDILICPHFLDDDCVCRKPKIKMIEPWLDKIDLKKSYVIGDRDTDMQLSNNLKIKGIKYKEDICNWLHITKYIIKHNRYAEIIRRTKETKVSIKVWLDLEETSKIDTGVKFFDHMLEQLSVHSGICMNISVQGDLDIDDHHTIEDTGIVLGEALLQALGKKNGLSRFGFYLPMDESRSNCIMDISNRPYLNFKAKFNHKMAGDLSTNMVEHFFYSLCYSMKITLHLYAEGKNDHHCIESLFKVFGRTLRQAIKIEGNMLPTSKGIL
What are the official names of this protein?
Histidine biosynthesis bifunctional protein HisB.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN558_HUMAN
Sequence: MAAVILPSTAAPSSLFPASQQKGHTQGGELVNELLTSWLRGLVTFEDVAVEFTQEEWALLDPAQRTLYRDVMLENCRNLASLGCRVNKPSLISQLEQDKKVVTEERGILPSTCPDLETLLKAKWLTPKKNVFRKEQSKGVKTERSHRGVKLNECNQCFKVFSTKSNLTQHKRIHTGEKPYDCSQCGKSFSSRSYLTIHKRIHNGEKPYECNHCGKAFSDPSSLRLHLRIHTGEKPYECNQCFHVFRTSCNLKSHKRIHTGENHHECNQCGKAFSTRSSLTGHNSIHTGEKPYECHDCGKTFRKSSYLTQHVRTHTGEKPYECNECGKSFSSSFSLTVHKRIHTGEKPYECSDCGKAFNNLSAVKKHLRTHTGEKPYECNHCGKSFTSNSYLSVHKRIHNRWI
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 558.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNPA_PSE14
Sequence: MSRDFSREKRLLTPRHFKAVFDSPTGKVPGKNLLLLARNNDLDHPRLGLVIGKKSVKLSVERNRLKRLMRESFRQHQDSLVGWDIVIVARKGLGDVENPELIQYFGKLWKRLARSRPIPEEKSEPAGVDSPDA
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: Y2370_ENT38
Sequence: MFCVIYRSAKRDQTYLYVEKRDDFSRVPEELMKGFGTPQLAMLLPLDGRKQLVNADLEKVKTALKDQGYYLQLPPPPENLLKQHLEGEGKN
What are the official names of this protein?
YcgL domain-containing protein Ent638_2370.
Protein: RSMH_STRSX
Sequence: MTKEFNHTTVLLHETVDMLDIKPNGIYVDATLGGAGHSEYLLSQLTDGGHLYAFDQDQTAIDHAHIRLASYIEKGQVTFIRDNFRNLKTRLAELGVTEIDGICYDLGVSSPQLDERERGFSYKQDAPLDMRMNREGHLTAYDVVNNYDYHDLVRIFFKYGEDKFSKQIARKIEQARAVKPIETTTELAELIKSAKPAKELKKKGHPAKQIFQAIRIEVNDELGAADESIQQAIDLLALDGRISVITFHSLEDRLTKQLFKEASTIDVPKGLPFIPDDLKAPLELVNRKPILPSQEELEANNRAHSAKLRVAKKVHK
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPE_SERP5
Sequence: MTCPVIELAQQLIKRPSLSPHDEGCQALMIERLEAIGFTVEPMPFGDTLNFWAWRGEGQTLAFAGHTDVVPTGDEKRWDNPPFEPTIRDGMLYGRGAADMKGSLAAMVVAAERFVAANPHHQGRLAFLITSDEEASATHGTVKVVEALMARNERLDYCLVGEPSSTERVGDVVKNGRRGSITANLHIHGIQGHVAYPHLADNPVHRAMPALNELVAIEWDRGNEFFPPTSMQIANVQAGTGSNNVIPGEMFVQFNFRFSTESTDATIKQRVEELLERHQLNYSIEWRLSGQPFLTARGALVDAVVNAVEHYSELTPQLLTTGGTSDGRFIAQMGAQVVELGPVNATIHKVNECVHAADLQLLSRMYQRIMEQLVA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: SMA4_CAEEL
Sequence: MFHPGMTSQPSTSNQMYYDPLYGAEQIVQCNPMDYHQANILCGMQYFNNSHNRYPLLPQMPPQFTNDHPYDFPNVPTISTLDEASSFNGFLIPSQPSSYNNNNISCVFTPTPCTSSQASSQPPPTPTVNPTPIPPNAGAVLTTAMDSCQQISHVLQCYQQGGEDSDFVRKAIESLVKKLKDKRIELDALITAVTSNGKQPTGCVTIQRSLDGRLQVAGRKGVPHVVYARIWRWPKVSKNELVKLVQCQTSSDHPDNICINPYHYERVVSNRITSADQSLHVENSPMKSEYLGDAGVIDSCSDWPNTPPDNNFNGGFAPDQPQLVTPIISDIPIDLNQIYVPTPPQLLDNWCSIIYYELDTPIGETFKVSARDHGKVIVDGGMDPHGENEGRLCLGALSNVHRTEASEKARIHIGRGVELTAHADGNISITSNCKIFVRSGYLDYTHGSEYSSKAHRFTPNESSFTVFDIRWAYMQMLRRSRSSNEAVRAQAAAVAGYAPMSVMPAIMPDSGVDRMRRDFCTIAISFVKAWGDVYQRKTIKETPCWIEVTLHRPLQILDQLLKNSSQFGSS
What is the function of this protein?
Involved in TGF-beta pathway.
What are the official names of this protein?
Dwarfin sma-4, MAD protein homolog 3.
What is the protein family that this protein belongs to?
Belongs to the dwarfin/SMAD family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RR9_NEPOL
Sequence: MDHTSSVGLRKTGRRKCAVAQVRIIEGTGQLTINQRPGVPYLQYNPAYLLAAQGALDVTELTNRYDTIVKTKGGGLTGQAEAIKLGLARALCSLHIKHRKALKPQGYLTRNPLRKERKKYGLKKARKAPQFSKR
What are the official names of this protein?
30S ribosomal protein S9, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: VANG2_XENTR
Sequence: MDNDSQYSGYSYKSGHSRSSRKHRDRRERHRSKSREGSRGDKSVTIQAPGEPLLDNESTRGEDRDDNWGETTTVVTGTSEHSISHDDITRITKDMEDSAKLDCSRHLGVVIGGALALLSFLTPIAFMLLPQILWREDLEQCGTACEGLFISVAFKLLILLLGSWALFFRRPKAFFPRVFVFRALLMVLVFLLVVSYWLFYGVRILESRDKNYQGIVQYAVSLVDALLFVHYLAVVLLELRQLQPQFTVKVVRSTDGASRFYNIGHLSIQRVAVWILENYYHDFPVYNPALLNLPKSILSKKMSGFKVYSLGEENTTNNSTGQSRAVIAAAARRRDNSHNEYYYEEAEHERRVRKRKARLVVAVEEAFTHIKRLQDEDQKNPREIMDPREAAQAIFASMARAMQKYLRTTKQQPYHTMESILHHLEFCITHDMTPKAFLERYLGPGPTIQYHKDRWLAKQWTLVSEEPVTNGLKDGVVFVLKRQDFSLVVSTKKIPFFKLSEEFVDPKSHKFVMRLQSETSV
What is the function of this protein?
Has a role in non-canonical Wnt/planar cell polarity (PCP) signaling; can recruit dvl/dsh and prickle from the cytoplasm to the plasma membrane.  Acts in a PCP complex to regulate the polarized assembly of fibronectrin on the surface of the mesoderm during gastrulation.  Regulates convergent extension in both dorsal mesoderm and neural tissue without affecting cell fate.  Regulates neural fold closure during neurulation.  May be required for cell surface localization of fzd3 and fzd6 in the inner ear (By similarity).
What are the official names of this protein?
Vang-like protein 2, Protein strabismus, Van Gogh-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the Vang family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Cell membrane localization is regulated by prickle.
Protein: KN12C_ORYSJ
Sequence: MEMLRRNLKRQASRSLSAFAVSSPRAGAVAAADADQENLHPNLAAASPPMSPAAKNSSAAPGASPRSSKPVPTSAAPPSKAAAEGEQASAPANEAPAVKVVVRVRPTVSRPVDGKDLFFVRKTSPCSVAVGDRSFAVDGFLDDRASQADAFDLIGVPMIESALAGFNSSLVCYGQSGTGKTYTMFGALAAMVDSSSDHADRGVVPRVFQNLFAQIQGRQESSPEKQTSYQCRCSFLEVHNEQINDLLDPSQRNLQIRENAGNGIHVENLTDEYVSTVEDVNQILMKGLSNRKVGTTSMNLKSSRSHVIFSCVIEAWSKGFSNGFSSSRTSRITFVDLAGPDNDELDGGNKHCTREERYVKKSLSKLGKLVNILSEAPETQKDDSPHKQSCLTHVLKDTLGGNSRVTFLCSISSEHRCRTTTLSTLRFGERAKLMSNKAVVNEISEDDVNGLSDQIRQLKDELIRTKSGDTEPCKNGYFSAQNARESLHNLRVSLNRSLILPHIEVDSEEEMDVDEEDVQELRDQIRKLHSSSEDTFDDFMDAESGDDTPCSKGNPKTSEEDDQPVIDDCEDPIQEEHEVLSSTKVDQDLVSDRKSFLSVSASPHLSPMQDPTLCSSPKIHNKARKSITSPGLSPSKLSVSDCPGDEVSRKSAVRSSLQSSKLSPTDSLAASLQRGLHIMEYHEQNQGPRKSFVGLSFDHFALNPRQSVAKVSSGVLASPERKGATSSALCSSCKKAIDTDGNQKDNINAEKQIVIATSVVPEVKDDITASTIASKRQTELEALCEEQADKIKELSNLVDQYKKCSEDAQNSDGTEPTKELVDEAKVGEQHGELNVNDREELLSEIQRLKDQLKQQAGESTNVSLLEHLRNGSTDQEYELDREREKWMESESKWICLTEELRVDLESNRMLAEKTEMELSNEKKCTAELDDALQRAIYGHARIIEHYAELQEMYNDLLERHRRVMEGISEVKRAAAKAGRKGCGTAFAAALAAELSTVRIDREKERAQLKEQNRRLRIQLRDTAEAVHAAGELLVRLREAEEASTQEKERSAAMQQENDKLKKQLEKMKKKHEMEMETMKHFLADSRLPESALGGFYRQESEDVPEYNNHATSTCDDDQSWRAAFTSAYE
What are the official names of this protein?
Kinesin-like protein KIN-12C.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-12 subfamily.
Protein: TR106_MOUSE
Sequence: MLTVAEGILLCFVTSGSVLGVLGNGFILHANYINCVRKKFSTAGFILTGLAICRIFVICIIISDGYLKLFSPHMVASDAHIIVISYIWVIINHTSIWFATSLNLFYLLKIANFSHYIFFCLKRRINTVFIFLLGCLFISWSIAFPQTVKIFNVKKQHRNVSWQVYLYKNEFIVSHILLNLGVIFFFMVAIITCFLLIISLWKHNRKMQLYASRFKSLNTEVHVKVMKVLISFIILLILHFIGILIETLSFLKYENKLLLILGLIISCMYPCCHSFILILANSQLKQASLKALKQLKCHKKDKDVRVTW
What is the function of this protein?
Putative taste receptor which may play a role in the perception of bitterness.
What are the official names of this protein?
Taste receptor type 2 member 106, T2R106, mT2R44.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ENO2_LACLS
Sequence: MSIITDIYAREVLDSRGNPTLEVEVYTEDGAFGRGMVPSGASTGEHEAVELRDGDKSRYNGLGTQKAVDNVNNIIAEAIIGYEVTDQQAIDRAMIALDGTENKGKLGANAILGVSIAAARAAADELGVPLYNYLGGFNAKVLPTPMMNIINGGSHSDAPIAFQEFMIVPVGAPTFKEALRWGAEIFHALKKILKARGLETAVGDEGGFAPKFDGTEDGVETILKAIEAAGYKAGEDGVMIGFDCASSEFYENGVYDYTKFEGEGGKKLSASEQVDYLEELVSKYPIITIEDGMDENDWDGWKILTERLGKKVQLVGDDFFVTNTKYLERGIRENASNAILIKVNQIGTLTETFEAIEMAKEAGFTAIVSHRSGETEDSTISDIAVATNAGQIKTGSLSRTDRMAKYNQLLRIEDQLAEVAQYKGLKAFYNLKK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase 2, 2-phospho-D-glycerate hydro-lyase 2, 2-phosphoglycerate dehydratase 2.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: MED32_ARATH
Sequence: MDNIVDSLNKAYEKFVLASAGVLESKESAGGQKALLTDTALENFKEKWELFRVACDQAEEFVESVKQRIGSECLVDEATGLTTTAAGGQAPAAVTGAATSLPPISAVRLEQMSRAVRWLVLELQRGSGVAPGSVHSSSTGFDSRFSEDSTQ
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors.
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 32, Mediator of RNA polymerase II transcription subunit 2.
What is the protein family that this protein belongs to?
Belongs to the mediator complex subunit 32 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RTEL1_DANRE
Sequence: MPVIKLKGINVDFPFTPYPCQEDYMSKVIECLQKKVNGVLESPTGTGKTLCLLCSTLAWRDHFKDTISARKITERMGGAELFADRPMSSWGTAATDGDTPTYYTDIPKIIYASRTHSQLTQVVNELKNTSYRPKICVLGSREQLCINQEVMRHESNHIKVHMCRAKVSSRSCIFYNNVDEKSTDKEIVNSILDVEDLVKTGKKQRVCPYYLSRSLKQHADVIFMPYNYLLDPKSRRAHNIELKGAVVIFDEAHNVEKMCEESTSFDLTPHDLISAIEAVDRLLREQASDISKADSAEDFNVESLNSGLKMDITTIAKVKQILMDLETAINDFEMPANNQGITKPGSFIFELFEMANVNSKTKTETVEAMEQITGYLAGRPGVFLNTSGLQKVADIIQLVFVAEPAEGSKKSQTGNSLKEFKVHIHPDNSNFKKKQITDVWASSSTKKQGNVLSYWCFSPGFSMQELLRQEVRCIILTSGTLSPLSSFTCEMQIPFPVSLENPHVIQRDQIFVSIIEKGPDGVQLSTAFDRRFVPENMSSMGNTLVNLSRVVPHGLLVFFPSYPVMDKTLEFWRAKGHADRIENVKPMFVEPRGKGTFTEVIDGYYGKVDDPNSSGGSFFAVCRGKASEGLDFADTYGRGVVITGLPFPPRMDPRVVLKMQYLDEMCRNKISGVKYLTGQEWYRQQASRAVNQAIGRVIRHREDYGAIFLCDHRFKSADARNQLPSWVRPYVKIYDGFGTMVRDVAQFFRTAQKTRPVPVKKGKAEGHENQADTRLLNTGSSCLTKSVWPSDIYQKAKTLDAHVPSLKRRKLDSEEHSGREGAARLCIQYEMEMTSKRKPVSLLDALDDTTDKEEREDTMVGEERASHLSTLSLQHDKRLDDESRGGKRKIKVVQERETVTSHTAKTGKAFMMELRRCLSHENFKLIMEALQSYKTADNLNNLLATVAEPLIQDHNTHSLLRGLYQFIRPHHKKEYDERCLELTGEGCGYKQEHSLSREEKEALRHNSVKAEIPPVNPPIEQLNSSRLLNQGGSHLGTIQLNGGEVNVRSEEQKPQTSIKEGPSCSSLLSDIKQAIGAEKTRQMFSALQAYKTSNNYEQMVSTVVSLLTERDEDIALLERLSVLIRPQHRKQFGELLKSLTGNDSAVVQDSDIGSSQQLSYLEERLNARYRPSFHECC
What is the function of this protein?
ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability.  Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis.  Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates.  Also disassembles T loops and prevents telomere fragility by counteracting telomeric G4-DNA structures, which together ensure the dynamics and stability of the telomere.
What are the official names of this protein?
Regulator of telomere elongation helicase 1.
What is the protein family that this protein belongs to?
Belongs to the helicase family. RAD3/XPD subfamily.
What are the subcellular locations of this protein?
Nucleus.