PharMolix/UniProtQA huggingface dataset:
Protein: RK2_ORYNI
Sequence: MAKHLYKTPIPSTRKGTIDRQVKSNPRNNLIHGRHRCGKGRNSRGIITARHRGGGHKRLYRKIDFRRNQKDISGRIVTIEYDPNRNAYICLIHYGDGEKGYILHPRGAIIGDTIVSGTKVPISMGNALPLTDMPLGTAIHNIEITRGRGGQLARAAGAVAKLIAKEGKSATLRLPSGEVRLVSQNCLATVGQVGNVGVNQKSLGRAGSKCWLGKRPVVRGVVMNPVDHPHGGGEGKAPIGRKKPTTPWGYPALGRRTRKRKKYSDSFILRRRK
What are the official names of this protein?
50S ribosomal protein L2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YIDD_ECO57
Sequence: MAPPLSPGSRVLIALIRVYQRLISPLLGPHCRFTPTCSSYGIEALRRFGVIKGSWLTVKRVLKCHPLHPGGDDPVPPGPFNTREH
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: IF1_RHOJR
Sequence: MAKKDGAIEVEGRVVEPLPNAMFRIELENGHKVLAHISGKMRQHYIRILPEDRVVVELSPYDLSRGRIVYRYK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIG_RHIEC
Sequence: MLKLYDVEVGSRLLLGTARYPSPAVLAEAVRRAKTEIVTVSLRREAAGGKAGGAFFELIRELGVRVLPNTAGCHSVQEAVLTAKLARDVFRTDWIKLEVIGHHDTLQPDVFGLVEAARILSGEGFQVFPYTTDDLVVAEKLLDAGCRVLMPWCAPIGSAMGPVNPMALRAFRAHFPDVPLIVDAGVGRPSHAAAVMEYGYDAVLLNTAVAGAGDPAAMAEAFALAIDAGRIAHSAVPLEPRDMAVPSTPVIGKAVFS
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDH_YERPB
Sequence: MKVAVLGAAGGIGQALALLLKTQLPSGSDLSLYDIAPVTPGVAVDLSHIPTAVNIKGFSGEDATPALQGADIVLISAGVARKPGMDRSDLFNVNAGIVRNLVEQIARTCPNALIGIITNPVNTTVAIAAEVLKKAGVYDKNKLFGITTLDTIRSNTFVAELKGKQPQDIEVPVIGGHSGVTILPLLSQIPGVSFTEQEVADLTKRIQNAGTEVVEAKAGGGSATLSMGQAAARFGLSLVRALQGESNVVECSYVEGDGKYARFFAQPILLGKNGVAERKDIGKLSAFEQQALENMLDVLHKDIELGEKFVNQ
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: ACYP_LISMF
Sequence: MARDTAILRVTGFVQGVGFRYTTKHVAYKYDISGTVKNLDDGSVEIHAIAEEENLNKFIDAIKKGPSPGCRIEHVYIYKGAPVEERKTFDIVY
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: CSPLK_SELML
Sequence: MATLPVSLVFAFKNRPKCVITRAQYVKEATDLAKRSNELGSPTRRKDESFGKISIQELVFLEDDVQALNEAFPQGEKADTSWAVTVLFSLAKLVFGILGLALSVIWPLHIIVFMLVNPPAFPFLNQVFIQLDSAWGLLGTTAFAIFCYYLVMSVISGEMHSIHPMK
What are the official names of this protein?
CASP-like protein SELMODRAFT_416721.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NUSB_ECOUT
Sequence: MKPAARRRARECAVQALYSWQLSQNDIADVEYQFLAEQDVKDVDVLYFRELLAGVATNTAYLDGLMKPYLSRLLEELGQVEKAVLRIALYELSKRSDVPYKVAINEAIELAKSFGAEDSHKFVNGVLDKAAPVIRPNKK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: UVSSA_XENTR
Sequence: MDQKLSELVEVLTTSGEPQLNPEKLKELKKICRSSDEHINHVYHLLMTQLNQEHAEIRLSAFQIVTELFARSHLFRTLLISNFQEFLELTVETDHEQPLPPPKEVAQKMKILAIKTVQEWHEKFGEAYKKLSLGYHFLKQNKKIDFQDVRSRTQAERKREEEKQRRLENIYKEKVKKATAEMEDMLEEIQSSLTEMENCFRLLLPDPREFAVFTDEKDFASDMRTKPTSQSPSHSKSTSQSSAYSKSTSQVSFDNDDEQPCCSKNLPPFPSSCTSSASGAERSLGEGAKESDKSARKSDTDDSDGDYEGSREAFLRDHGLGSHAYSLSLEISTDLKVNENENNTDVLNNLMDAHKLLKQKYWPAVQSWIQLFTKAGTNSESLKCAIDVKKEIEAALKKYKEMNIDCHTKERKVMTASDDDDDDDEFEEVPEKEGYEPHIPDHLREEYGLEPSASKQPGKKTEVKRPNVPQVPPSQKRINDELNPTCAAATMKTMKDKMAKALPGSSRNAGEPKSKCPKRETDLSQAPVAPCGLDLHHWGEEQPSAGKMLKFSSLHRFWAPNEVDEEVESKELEALVKTRYVTLPGKFEPVKHKCLAPMPNGSLCERQDRYKCPFHGKIVPRDAIGVPINAEDRAREAREKFEKQGEEQDWRDPELMREIEQATGVDLGSSKCPVKGKGKGVKRNLKKKYPNLTDLKQKANTSRSRLEKKVFNTGSVKRVISAMNQADKRRHEKFANQFNYALN
What is the function of this protein?
Factor involved in transcription-coupled nucleotide excision repair (TC-NER), a mechanism that rapidly removes RNA polymerase II-blocking lesions from the transcribed strand of active genes.  Facilitates the ubiquitination of the elongating form of RNA polymerase II (RNA pol IIo) at DNA damage sites, thereby promoting RNA pol IIo backtracking and access by the TC-NER machinery to lesion sites (By similarity).
What are the official names of this protein?
UV-stimulated scaffold protein A.
What is the protein family that this protein belongs to?
Belongs to the UVSSA family.
What are the subcellular locations of this protein?
Chromosome. Note=Accumulates at UV DNA damage sites.
Protein: YHJV_ECOLI
Sequence: MQHNTLSKHNQKLPFTRYDFGWVLLCIGMAIGAGTVLMPVQIGLKGIWVFITAAIIAYPATWVVQDIYLKTLSESDSCNDYTDIISHYLGKNWGIFLGVIYFLMIIHGIFIYSLSVVFDSASYLKTFGLTDADLSQSLLYKVAIFAVLVAIASGGERLLFKISGPMVVVKVGIIVVFGFAMIPHWNFANITAFPQASVFFRDVLLTIPFCFFSAVFIQVLNPMNIAYRKREADKVLATRLALRTHRISYITLIAVILFFAFSFTFSISHEEAVSAFEQNISALALAAQVIPGHIIHITSTVLNIFAVLTAFFGIYLGFHEAIKGIILNLLSRIIDTKKINSRVLTLAICAFIVITLTIWVSFRVSVLVFFQLGSPLYGIVSCLIPFFLIYKVAQLEKLRGFKAWLILLYGILLCLSPLLKLIE
What are the official names of this protein?
Inner membrane transport protein YhjV.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SELU_CROS8
Sequence: MQKDAQRRPDSDDALALITRGVTLIDVRAPVEFAQGAMPGAINLPLMNNDERAAVGTCYKQHGQQAALALGHRLVYGEVREARLNAWRLACERHPEGFLCCARGGMRSYIVQQWLRERGIDYPLVEGGYKRLRQEAMDATDRLSRLPMVLIGGCTGSGKTQLVKALPTGIDLEGLAHHRGSSFGRTLTPQRAQASFENHLAAAMLNHHARWTTLSNPFWVLEDEGKMIGANHLPAVLREQMLQAPVAVVEEPLERRLERLREEYFVQMQAAFQAALGDEAAGWRAYGDYLHHGLYAIRRRLGLARYAELAALQEAALARQQRTGETHAHFAWLAPLLEGYYDPMYRYQLEKKAQQIAFRGDYHQVDAWLRHRYCASR
What is the function of this protein?
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA).  Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
What are the official names of this protein?
tRNA 2-selenouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the SelU family.
Protein: VIP2_NICBE
Sequence: MQGTLTSRNTAINNVPSSGVQQSGNNLSGGRFVPNNLPSALSQIPQGNSHGHSGMTSRGGTSVVGNPGYSSNTNGVGGSIPGILPTFAAIGNRSSVPGLGVSPILGNAGPRMTNSVGNIVGGGNIGRSISSGAGLSVPGLASRLNMNANSGSGNLNVQGPNRLMSGVLQQASPQVLSMLGNSYPAGGPLSQNHVQAIGNFNSMGLLNDVNSNDGSPFDINDFPQLSSRPSSAGGPQGQLGSLRKQGLSPIVQQNQEFSIQNEDFPALPGFKGGNADYAMDPHQKEQLHDNTLSMMQQQHFSMGRSAGFNLGGTYSSNRPQQQLQHAPSVSSGGVSFSNINNQDLLSLHGSDVFQSSHSSYQQQGGGPPGIGLRPLNSSGTVSGIGSYDQLIQQYQQHQGQSQFRLQQMSTLGQPFRDQSLKSMQSQVAPDPFGMLGLLSVIRMSDPDLTSLALGIDLTTLGLNLNSAENLYKTFGSPWSDEPAKGDPEFTVPQCYYAKQPPPLNQAYFSKFQLDTLFYIFYSMPKDEAQLYAANELYNRGWFYHREHRLWFMRVANMEPLVKTNAYERGSYICFDPNTWETIHKDNFVLHCEMLEKRPVLPQH
What is the function of this protein?
Transcriptional regulator required for Agrobacterium-mediated stable genetic transformation by T-DNA integration in host genome, but not for T-DNA transient expression.
What are the official names of this protein?
Probable NOT transcription complex subunit VIP2, Protein VIRE2 INTERACTING PROTEIN2, NbVIP2.
What is the protein family that this protein belongs to?
Belongs to the CNOT2/3/5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS13_SACS2
Sequence: MSQQFKYVVRIFGQDVDGTMKLPYALAMVKGIGYNTAKAIIRKLGMDPNARLGELSDAEVKKVESVISDHTIKGLPSWLYNRRKDYESGLDLHLVTSDLIFYVRNDIEREKKSRSWRGVRHSLGLKVRGQRTRTTGRTGMTIGVARKKAAQPQSQQSSSQQQKSS
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: IF4A_KLULA
Sequence: MSDGITDIDENQIQSTYDKVVYSFDDLKLKEELLRGIFGYGFVEPSAIQQRAILPIIEGKDVLAQAQSGTGKTGTFSIAALQNIDEKIKAPQGLILAPTRELALQIQKVVMALAIHMDVKVHACIGGTSLQEDSEALRGGAQIIVGTPGRVFDMIDRRIFKTDNIKMFILDEADEMLSTGFKEQIYNIFTMLPPTSQVVLLSATMPGDVLEVTSKFMKDPVRILVKKDELTLEGIGQYYVNVEEEQYKYDCLTDLYDSISVTQAVIFCNTRRKVEELTERLRENNFTVSAIYSDLQQQERDTIMKEFRSGSSRILISTDLLARGIDVQQVSLVINYDLPSNKENYIHRIGRGGRFGRKGIAINFVTNKDIGAMRELERFYSTQIEELPSSISELFD
What is the function of this protein?
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome.  In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase eIF4A, Eukaryotic initiation factor 4A, eIF-4A, Translation initiation factor 1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. eIF4A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RH40_ORYSJ
Sequence: MSAGTAPAAPRYAPDDPSLPKPWRGLVDGTTGYLYYWNPETNITQYEKPLPPEDQLPPPPPLPPPPPRSGRGDRDRDRRDRSRSRTPPRRDHRDRDRDRDRRHDDHRSAPSHHHPLPAAAAIAADDPSTEAYRHRHEITVVGDNVPAPITSFETGGFPPEILKEIQRAGFSSPTPIQAQSWPIALQCQDVVAIAKTGSGKTLGYLLPGFMHIKRLQNNPRSGPTVLVLAPTRELATQILEEAVKFGRSSRISSTCLYGGAPKGPQLRDLDRGVDVVVATPGRLNDILEMRRISLKQVSYLVLDEADRMLDMGFEPQIRKIVKEIPPRRQTLMYTATWPKEVRRIAEDLLVHPVQVTIGSVDELVANSAITQNVELITPSEKLRRLEQILRSQDSGSKVLIFCTTKRMCDQLARTLTRQFGASAIHGDKSQSEREKVLSHFRSGRSPILVATDVAARGLDIKDIRVVINYDFPTGIEDYVHRIGRTGRAGATGVAYTFFCDQDSKYAADLIKILEGANQRVPRDLADMASRGGRGGRKRNRWATRSDRGGSHSELDSRYGGRDGLSGSSGRLDSSRSSRRHDYGDDGRSRRSGRGRSRSRSRSDSDRYSRSPKRSRRHSRSRTRSRSRSRSRSYTRNRRASRSRSRSPGASRRHERSATGSGSALPDSGHGERKRTPEADPSRNHTNHSDPKDDRHPEDGKVGKVDLDRSPTPQDKSGPYSPAYNGKTSRSVSPGNQVEGNNKAAEVSKNPDPSSPPHHGKTREDEEEGMIDEDGEIADDPRANATVQNGGDN
What is the function of this protein?
ATP-dependent RNA helicase involved nonsense-mediated mRNA decay and ribosome biogenesis through rRNA processing.
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase 40.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PMP22_BOVIN
Sequence: MLLLLLGIIVLHVAVLVLLFVSTIVSQWMVGNGHATDLWQNCSTSLMGSVQHCFSSSANEWLQSVQATMILSIIFSVLSLFLFFCQLFTLTKGGRFYITGVFQILAGLCVMSAASIYTVRHPEWHFNSDGSYGFAYILAWVAFPLALLSGVIYVILRKRE
What is the function of this protein?
Might be involved in growth regulation, and in myelinization in the peripheral nervous system.
What are the official names of this protein?
Peripheral myelin protein 22, PMP-22, PAS positive glycoprotein, PASII.
What is the protein family that this protein belongs to?
Belongs to the PMP-22/EMP/MP20 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CLPS_ALKEH
Sequence: MTDKAGDWQEHGPQVEEAPPQVKRPPLFKVIILNDDYTPMDFVVEVLQKFFHMDRARATQVMLHVHTRGEGVCGVFSRDVAETKVNQVNDWSRQHEHPLMCTLKEA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: NUOI_ANAPZ
Sequence: MLYCVQFGRRVIRLVSATVHGFFLTLLAMFKPKVTLRYPHEKGPLSTRFRGEHALRRYESGEERCIACKLCEAICPAQAITIEAEERSDGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEYSTETREELMYNKEKLLANGDIWEEALRYRIKKNQPYY
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ACT1_CRIJA
Sequence: MNRLIILCLVAATIYSTIALPMKEDISNEERPTSVNEKPVKKSVAVAGAVIQGAALAFQVLDKILTSLGGIGRKIAIGVDNESGMKWAARNVYFYSGTSDTVLPYSVPHSKAFLYGARKTRGSVRGAVGVLAYSMSDGNTLGILFSVPYDYNWYSNWWNIKVYRGYKRANKWMYHDLYYYARPHKGNNEWHEKSLGYGLKSKGFMTSSGQTKLEIRVSRA
What is the function of this protein?
Probably acts in predation (PubMed:29649486).  Pore-forming protein that forms cations-selective hydrophilic pores of around 1 nm and causes cytolysis.  Pore formation is a multi-step process that involves specific recognition of membrane sphingomyelin (but neither cholesterol nor phosphatidylcholine) using aromatic rich region and adjacent phosphocholine (POC) binding site, firm binding to the membrane (mainly driven by hydrophobic interactions) accompanied by the transfer of the N-terminal region to the lipid-water interface and finally pore formation after oligomerization of monomers (By similarity).  Shows hemolytic activity on equine erythrocytes (PubMed:29649486).  Hemolysis is moderately inhibited in presence of sphingomyelin, suggesting that this protein targets sphingomyelin (PubMed:29649486).
What are the official names of this protein?
Deep-sea actinoporin Cjtox I, DELTA-actitoxin-Cja1a, DELTA-AITX-Cja1a.
What is the protein family that this protein belongs to?
Belongs to the actinoporin family. Sea anemone subfamily.
Protein: MOEA_STAEQ
Sequence: MSVEKRTPISVKEAIKRIMKQHVEVKNININLDESLGHILAEDIVATYDIPRFNKSPYDGFAIRSEDSQGASGENRIEFEVIDHIGAGSVSEKTIDKNQAIRIMTGAQIPSGADAVVMFEQTIESETTFTIRKSFKHLENISLQGEEIKAGDIVLHKGMRINSGVIAVLATYGYTKVRVARKPTVAVIATGSELLEVEDELEPGKIRNSNGPMIKALAKQFGIQVGMYKVQHDNLEKSIEVVKKALSEHDLVITTGGVSVGDFDYLPEIYKSIQAQILFNKVAQRPGSVTTVAFADGKYLFGLSGNPSACYTGFELYVKPAVNKLMGAKACYPQIIKATLMEDFNKANPFTRLIRAKATLTKAGMTVIPSGFNKSGAVVAIAHANAMIMLPGGTRGFKAGNIVDVILTESNSFEEELIL
What is the function of this protein?
Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.
What are the official names of this protein?
Molybdopterin molybdenumtransferase, MPT Mo-transferase.
What is the protein family that this protein belongs to?
Belongs to the MoeA family.
Protein: HIS4_STAAC
Sequence: MIELWPAIDLIGSTSVRLTEGKYDSEEKMSRSAEESIAYYSQFECVNRIHIVDLIGAKAQHAREFDYIKSLRRLTTKDIEVGGGIRTKSQIMDYFAAGINYCIVGTKGIQDTDWLKEMAHTFPGRIYLSVDAYGEDIKVNGWEEDTELNLFSFVRRLSDIPLGGIIYTDIAKDGKMSGPNFELTGQLVKATTIPVIASGGIRHQQDIQRLASLNVHAAIIGKAAHQASFWEGLK
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_ENT38
Sequence: MAKQDFYEILGVPKTAEEREIKKAYKRLAMKFHPDRNQGDKEAEAKFKEIKEAYEILTDAQKRAAYDQYGHAAFEQGGMGGGGYGGGGFGGGGADFGDIFGDVFGDIFGGGRGRQRASRGADLRYNMELTLEEAVRGVTKEIRIPTLEECDICHGSGAKVGTKPQTCPTCHGSGQVQIRQGFFAVQQACPHCHGRGTLIKDPCNKCHGHGRVEKTKTLSVKIPAGVDTGDRIRLAGEGEAGEHGAQAGDLYVQVQVKQHAIFEREGNNLYCEVPINFAMAALGGEIEVPTLDGRVNLKVPGETQTGKLFRMRGRGVKSVRGGAQGDLLCRVVVETPVGLNDKQKQLLKELQESFGGPTGENNSPRSKSFFDGVKKFFDDLTR
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPF31_SCHPO
Sequence: MADVAKFLDRVEGSLNRGREIDRILSSFKLNAYDVLDILPGMSVDDIRNLYRKKSLMIHPDKNRDNPKAADAFDILKKAESDLVNDKIRESLDSAYTAARNQLLKEKKLSPNSEDVHSDQFLFDLKVRWREILIADEVARRRARQLDLANQQREQARQDEIARERKRRVESEKVWEETRDNRVGNWQDFLHKTKKNNLKKKNKKPRVLG
What are the official names of this protein?
J domain-containing protein spf31.
Protein: MINE_PROM4
Sequence: MTLRDLINKLLGRQQASAARARERLQLVLAHDRTDLSPDLLDQMREEILSVVAKYVEIDVEEGAVSLETEDRMTALVANLPIKRTLSGDIKLKEQSTESSASK
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: RIMP_STAAR
Sequence: MSKITEQVEVIVKPIMEDLNFELVDVEYVKEGRDHFLRISIDKEGGVDLNDCTLASEKISEAMDANDPIPEMYYLDVASPGAERPIKKEQDFQNAITKPVFVSLYVPIEGEKEWLGILQEVNNETIVVQVKIKARTKDIEIPRDKIAKARHAVMI
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAX_GEOSL
Sequence: MLLVIDVGNTNIVLGIYDGERLVRDWRVSTDKARTTDEYGILINELFRLAGLGLDQIRAVIISSVVPPLTGVLERLSLGYFGMRPLVVGPGIKTGMPIQYDNPREVGADRIVNAVAGYEKYRTSLIIVDFGTATTFDYVNRKGEYCGGAIAPGLVISTEALFQRASKLPRVDIIRPSAIIARNTVNSMQAGIYYGYVGLVDEIVTRMKAESKDAPRVIATGGLASLIAPESKTIEAVEEYLTLEGLRILYERNRE
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NHAB_ECOBW
Sequence: MEISWGRALWRNFLGQSPDWYKLALIIFLIVNPLIFLISPFVAGWLLVAEFIFTLAMALKCYPLLPGGLLAIEAVFIGMTSAEHVREEVAANLEVLLLLMFMVAGIYFMKQLLLFIFTRLLLSIRSKMLLSLSFCVAAAFLSAFLDALTVVAVVISVAVGFYGIYHRVASSRTEDTDLQDDSHIDKHYKVVLEQFRGFLRSLMMHAGVGTALGGVMTMVGEPQNLIIAKAAGWHFGDFFLRMSPVTVPVLICGLLTCLLVEKLRWFGYGETLPEKVREVLQQFDDQSRHQRTRQDKIRLIVQAIIGVWLVTALALHLAEVGLIGLSVIILATSLTGVTDEHAIGKAFTESLPFTALLTVFFSVVAVIIDQQLFSPIIQFVLQASEHAQLSLFYIFNGLLSSISDNVFVGTIYINEAKAAMESGAITLKQYELLAVAINTGTNLPSVATPNGQAAFLFLLTSALAPLIRLSYGRMVWMALPYTLVLTLVGLLCVEFTLAPVTEWFMQMGWIATL
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaB, Sodium/proton antiporter NhaB.
What is the protein family that this protein belongs to?
Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MDH_CITK8
Sequence: MKVAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAVDLSHIPTAVKIKGFSGEDATPALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKNLVQQIATTCPKACVGIITNPVNTTVAIAAEVLKKAGVYDKNKLFGVTTLDIIRSNTFVAELKGKLPTDVEVPVIGGHSGVTILPLLSQIPGVSFTEQEVADLTKRIQNAGTEVVEAKAGGGSATLSMGQAAARFGLSLVRALQGEKDVVECAYVEGDGQYARFFSQPLLLGKNGVEERKSIGKLSAFEQNALEGMLDTLKKDIALGEEFVNK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: YJP0_YEAST
Sequence: MQRFTALHYTPFPLLVFLSSYFPLKMHLFTRVFFLIASITLLYRPTQRGIYIDYKRIVDFDGDLISVQNIQDVYTQCLQLSLYSYHAISRLFSEEKSSVH
What are the official names of this protein?
Putative uncharacterized protein YJL150W.
Protein: MANB_ECOLI
Sequence: MKKLTCFKAYDIRGKLGEELNEDIAWRIGRAYGEFLKPKTIVLGGDVRLTSETLKLALAKGLQDAGVDVLDIGMSGTEEIYFATFHLGVDGGIEVTASHNPMDYNGMKLVREGARPISGDTGLRDVQRLAEANDFPPVDETKRGRYQQINLRDAYVDHLFGYINVKNLTPLKLVINSGNGAAGPVVDAIEARFKALGAPVELIKVHNTPDGNFPNGIPNPLLPECRDDTRNAVIKHGADMGIAFDGDFDRCFLFDEKGQFIEGYYIVGLLAEAFLEKNPGAKIIHDPRLSWNTVDVVTAAGGTPVMSKTGHAFIKERMRKEDAIYGGEMSAHHYFRDFAYCDSGMIPWLLVAELVCLKDKTLGELVRDRMAAFPASGEINSKLAQPVEAINRVEQHFSREALAVDRTDGISMTFADWRFNLRTSNTEPVVRLNVESRGDVPLMEARTRTLLTLLNE
What is the function of this protein?
Involved in the biosynthesis of the capsular polysaccharide colanic acid.
What are the official names of this protein?
Phosphomannomutase, PMM.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: Y1745_PSEPF
Sequence: MIISTTHSIEGRQITAYLDIVSAESVQGVNVIRDMFAGMRDFFGGRSQTLERALKEARVQATDEIKERARALQADAVVGVDFEISMPAGKGGMVVVFATGTAVKLR
What are the official names of this protein?
UPF0145 protein Pfl01_1745.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: Y1118_SYNY3
Sequence: MLTSTTDIVQGRTIARYHGIVTAEVVYGTNALRDFFAGIRDLIGGRTGSYEQIFEKGHREAIAELTERAQKLGANGVIGVAVNTGTINIDDRGALLLITATGTAVTVD
What are the official names of this protein?
UPF0145 protein sll118.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.