PharMolix/UniProtQA huggingface dataset:
Protein: SYA_CAMJJ
Sequence: MDIRKAYLDFFASKGHEITPSSPLVPDDATLLFANAGMVPFKSIFTGEIPRPNPPRKTSCQTCIRAGGKHNDLDNVGYTARHHTFFEMLGNFSFGDYFKEQAIAYAWEFVTEVLKLPKDRLYVTVHENDDEAFNLWQKHIQKERIYKFGDKDNFWQMGDTGPCGPCSEIFYDQGEEHFNSSEDYMGGDGDRFLEIWNLVFMQYERSADGVLSPLPKPSIDTGMGLERVTAIKEGKFSNFDSSLFMPIINEISKLCNKTYIYESGASFRVIADHIRSSVFLLAQGVSFDKEGRGYVLRRILRRALRHGYLLGFKQAFMYKLVDIVCDLMGGHYTYLNEKKDFIKEQIRLEEERFLSTIENGIEIFNEELKNTKEIFSGEVAFKLYDTYGFPLDLTADMLREKNLKVDEEKFELLMNEQKARAKASWKGSGDKTASGDFKNLLEKFGENHFVGYEKAECESKILALLDEDFKEVSTLKDAGWVMLENTPFYATSGGQSADSGFIAKREVLDTQKFFNLNLSFVKAGEELKVGDIVHARIDTEKREQIARHHSATHLLHHALREILGSHVSQAGSLVESNKLRFDFTHHKALNKEELESIEKRVNEMIINSSEAILENMPLEEAKKSGAIALFNEKYQGNVRVLTLGESKELCGGTHVKNTAQIGSFYIVKESGVSAGVRRIEAVVSKAALEFVKNQLEELSKVKDELKNNDILNGVKKLKNEILSLKNELKNSSKTELDSKNIQGVEICVKRIDNGDIKAMIDDFKNKFAKAVILLIQVKDEKITLAAGVKDAPLKAGALVKEAAQILGGNGGGRDDFATAGGKDLSKINEALKQSLETIEKAL
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y145_ARCFU
Sequence: MCRCRCMAMMSFVAIVTPLTMLTGLIDWKYRYDMRKVPIIQRKVITGIVGYVFVVVYVVLHSLTDYSLAALAMALVFFAITGEYGGKLVHGARTLLCLKNLRKGSSQKSNPN
What are the official names of this protein?
Uncharacterized protein AF_0145.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: OBG_COLP3
Sequence: MKFVDEVEIRVEAGDGGNGCVSFRKEKFIEYGGPNGGDGGDGGDVYLMADEGLNTLIDYRFERFHRAKRGQNGQPQNCTGKGSEDLVLKVPVGTRAVDQDTGEQIGDLTYKGQKMLVAKGGWHGLGNLRFKSSTNRSPRQRTDGTPGEIRSLKLELLLLADVGLLGLPNAGKSTLIRSVSAATPKVADYPFTTLVPNLGVVRLDTQRSFVIADIPGIIEGAADGAGLGTQFLKHLERCRILLHVIDIMPVDGSDPLENAKVIISELEQHNEKLAGKPRWVVFNKLDLVLEEEAKEITDAIIAGLDWKGEVHSISAFNRSGTKELTQKVMTFIEELPPEEEEVIDGKTVEFKWDTYHEETIAAHSQDDDLDDDDWDEDDYDVEVEYRQ
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CALRL_XENTR
Sequence: MGLLLRSALFKYIIIVLIMLNLRGYVLAEQEQGSQIPLEEIIQVGVTRNKIMTAQYECYQKIMQEPANGKEGHFCNRTWDGWLCWGDVSAGVISEQRCPDYFQDFDPSEKVTKECGKNGHWFRHPDSNRTWTNYTRCNTFTHEKVKTALNLYYLTIIGHGLSIASLLISLGIFFYFKNLSCQRITLHKNLFFSFVCNSIITIISLSAVANNQALVATNPVSCKISQFIHLYLMGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYLLGWGFPLIPACIHAVARSLYYNDNCWISSETHLLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFVLFPWKPEGRIAEEIYDYVMHILMHYQGLLVATIFCFFNGEVQAVLKRHWNQYKIQFGSSFAHSEGLRSASYTVSSISEIQGTTYTHDYSEQSNGKNCHDMENVFFKTEKQYM
What is the function of this protein?
Receptor for calcitonin-gene-related peptide (CGRP) (By similarity).  Receptor specificity may be modulated by accessory proteins.  The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity).
What are the official names of this protein?
Calcitonin gene-related peptide type 1 receptor, CGRP type 1 receptor, Calcitonin receptor-like receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VF219_IIV3
Sequence: MSATPLFKTYDPVEKLISQVGALASGGTGGGTTTNALATTGGTMTGNITMSGTSKITQATAPTVASDVTNKQYVDSAVSAVSAPQMSFAGWKLNNASFFEVNPTTQVKLFTNIDGIGANQWTDTTEDAISVSGGIFSIQNKSTSKTMWYICSAHFTGLSNKTAPTVAGALRFKFNDEDSGNPINSQWCVLRSFSTSNVPSPEASAPQVSGSNMMYATISVPPGTTRRISVIANNPSATDVMQLNQTDDVCQIMITRQS
What are the official names of this protein?
Uncharacterized protein 036R.
What is the protein family that this protein belongs to?
Belongs to the IIV-6 219L family.
Protein: SP5G_LACP7
Sequence: MQITDVRVRRVSKEGKMKAVVSITLDNEFVVHDIKVIEGEKGLFIAMPSRKAGDGEYRDIAHPINSITRDKIQSIILEKYELAALEGNIEEAE
What is the function of this protein?
Could be involved in septation.
What are the official names of this protein?
Putative septation protein SpoVG.
What is the protein family that this protein belongs to?
Belongs to the SpoVG family.
Protein: EFTS_ECOUT
Sequence: MAEITASLVKELRERTGAGMMDCKKALTEANGDIELAIENMRKSGAIKAAKKAGNVAADGVIKTKIDGNYGIILEVNCQTDFVAKDAGFQAFADKVLDAAVAGKITDVEVLKAQFEEERVALVAKIGENINIRRVAALEGDVLGSYQHGARIGVLVAAKGADEELVKHIAMHVAASKPEFIKPEDVSAEVVEKEYQVQLDIAMQSGKPKEIAEKMVEGRMKKFTGEVSLTGQPFVMEPSKTVGQLLKEHNAEVTGFIRFEVGEGIEKVETDFAAEVAAMSKQS
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPD_SYNAS
Sequence: MKPKVVAIVPAGGSGRRMQSSNPKQYFLINGMPVLVHTLLRLQQFPLIDEILLVVPHSDMVFVRDNIEKPYQLTKIRGIVAGGRERQDSVRNGLKCVVEKDEIVVIHDGVRPFVTEKILSRVIDAAHRSGAAIAAVPAMDTVKEVHSDGHISVTLDRKRIWLAQTPQAFHRRIIQEAYKKAVQDDYYGTDDASLVERLGIPVEVVPGSCTNIKITTPDDLILAEAFLKKEEGRI
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: EMC3_MOUSE
Sequence: MAGPELLLDSNIRLWVVLPIVIITFFVGMIRHYVSILLQSDKKLTQEQVSDSQVLIRSRVLRENGKYIPKQSFLTRKYYFNNPEDGFFKKTKRKVVPPSPMTDPTMLTDMMKGNVTNVLPMILIGGWINMTFSGFVTTKVPFPLTLRFKPMLQQGIELLTLDASWVSSASWYFLNVFGLRSIYSLILGQDNAADQSRMMQEQMTGAAMAMPADTNKAFKTEWEALELTDHQWALDDVEEELMARDLHFEGMFKKELQTSIF
What is the function of this protein?
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.  Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues.  Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices.  It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes.  By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins like the G protein-coupled receptors.  By regulating the insertion of various proteins in membranes, it is indirectly involved in many cellular processes.
What are the official names of this protein?
ER membrane protein complex subunit 3, Transmembrane protein 111.
What is the protein family that this protein belongs to?
Belongs to the EMC3 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: CML46_ARATH
Sequence: MTENQLYSFITMKSSLSKCKQSSSLSFPLFGLINFFLIGFFRWVSFAQLFFSRFWPLVQHQQCVSEKKSKDLEFQTSIKHEEYRDDDDDGLCREDVGMVMKSLGLSTDQENEGLQKQYSSKEVSNLFEEKEPSLEEVKQAFDVFDENRDGFIDPIDLQRVLTILGLKQGSNLENCRRMIRSFDGSKDGRIDFYGFVKFMENNFC
What is the function of this protein?
Potential calcium sensor.
What are the official names of this protein?
Probable calcium-binding protein CML46, Calmodulin-like protein 46.
Protein: CDKAL_XENLA
Sequence: MPAVCESLLDDIEDMVSATDPKPHDRQSARKNIVPRARKRNKNNIQEEEPPADSTIPGTQKIWIRTWGCSHNNSDGEYMAGQLAAYGYSITEQPEKADLWLLNSCTVKSPAEDHFRNSIKKAQEANKKVVVSGCVPQAQPRQDYMKGLSIIGVQQIDRVVEVVEETIKGHSVRLLGQKKDNGKRLGGARLDLPKIRKNPLIEIISINTGCLNACTYCKTKHARGELASYPVEELVDRATQSFQEGVCEIWLTSEDTGAYGRDIGTDLPTLLWKLVEVIPEGAMLRLGMTNPPYILEHLEEMAKILNHPRVYAFLHIPVQSASDSVLMDMKREYCIADFKRVVDFLKERVPGITIATDIICGFPGETDEDFKETLKLVEEYKFPSLFINQFYPRPGTPAAKMEQVLAHVKKRRTKELSQLFHSYDPYDHKIGQKQQVLVTEESFDSQYYVAHNRFYEQVLVPKDPDFMGKMVEVKIFEAGKHFMKGQPVQDSYIYTPSITKPLAKGEVSGLTEELKPPNNIPKSETLLEKHWERLQVFLFLTALLAAVIAFVGTKLV
What is the function of this protein?
Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
What are the official names of this protein?
Threonylcarbamoyladenosine tRNA methylthiotransferase, CDK5 regulatory subunit-associated protein 1-like 1, tRNA-t(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. CDKAL1 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: MMM1_BOTFB
Sequence: MTIPAPIPDKAESSLSFTQGLLLGQLSIVILIGAFIKFFIFGDPPSPDVTAALRATERRSRTLAHKRSLLTLRSSTPRRASQPLNRKRSSVLRNPAPLTTNAILSKTYYNVDSHQPESLDWFNVLIAQTIAQFRADAQHDDAILTSLTKVLNGGNRPDFLDEIKVTELSLGEDFPIFSNCRVIPVDEDGMTLGREGGAAGREHGRLQARMDVDLSDFITLAVETKLLLNYPKPLVAVLPVALAVSVVRFSGTLSISFVPGSPLNGSPTTLAFCFLDDYRLDLSIRSLVGSRSRLQDVPKIAQLIEARLHTWFDERCVEPRFQQIELPSLWPRKKNTRGGEDLDTGSDAGGIGRARSRDVERDLREEARKEVEAETGIRVGRSKLGVSLDVPDEGSEDGLRFRRKSKGRDEYAMPGSMPGLSMT
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Maintenance of mitochondrial morphology protein 1.
What is the protein family that this protein belongs to?
Belongs to the MMM1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: PSBJ_PROM1
Sequence: MSKLKGPDGRVGDRLPDGRPAISWQRRWTEGALPLWLVATAGGTAVIFVLGIFFYGSYTGIGNAG
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein J, PSII-J.
What is the protein family that this protein belongs to?
Belongs to the PsbJ family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: OMP_BORPE
Sequence: MKKTLLAAALLAGFAGAAQAETSVTLYGIIDTGIGYNDVDFKVKGANADDSDFKYNHSRFGMINGVQNGSRWGLRGTEDLGDGLQAVFQLESGFNSGNGNSAQDGRLFGRQATIGLQSESWGRLDFGRQTNIASKYFGSIDPFGAGFGQANIGMGMSAMNTVRYDNMVMYQTPSYSGFQFGIGYSFSANDKDADAVNRVGFATADNVRAITTGLRYVNGPLNVALSYDQLNASNNQAQGEVDATPRSYGLGGSYDFEVVKLALAYARTTDGWFGGQGYPVAVTLPSGDKFGGFGVNTFADGFKANSYMVGLSAPIGGASNVFGSWQMVDPKLTGGDEKMNVFSLGYTYDLSKRTNLYAYGSYAKNFAFLEDAKSTAVGVGIRHRF
What is the function of this protein?
Forms anion selective channels.
What are the official names of this protein?
Outer membrane porin protein BP0840.
What is the protein family that this protein belongs to?
To bacterial outer membrane proteins and porins.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: T22D3_PIG
Sequence: MDLVKNHLMYAVREEVEILKEQIRELVEKNSQLERENTLLKTLASPEQLEKFQSRLSPEEPAPETPEAPEAPGGSAV
What is the function of this protein?
Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11.  In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10.  In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation.  In vitro, suppresses AP1 and NFKB1 DNA-binding activities.  Inhibits myogenic differentiation and mediates anti-myogenic effects of glucocorticoids by binding and regulating MYOD1 and HDAC1 transcriptional activity resulting in reduced expression of MYOG (By similarity).
What are the official names of this protein?
TSC22 domain family protein 3, DSIP-immunoreactive peptide, DIP protein, Delta sleep-inducing peptide immunoreactor, Glucocorticoid-induced leucine zipper protein.
What is the protein family that this protein belongs to?
Belongs to the TSC-22/Dip/Bun family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localization depends on differentiation status of myoblasts. In undifferentiated myoblasts, localizes to the cytoplasm, but in differentiating myoblasts is localized to the nucleus (By similarity).
Protein: GLMU_PARL1
Sequence: MTTNAPGAVILAAGKGTRMKSRLPKVLHPIAGKPMLGHVLSAVSALGSERPVLVVGPGMDEVATYARGLVSGLTIAVQEKQLGTGDAVRAAAPHIDKKESVVLVVFGDTPLVRAETLADMTRRCEEGSDIVVLGFEAADPTGYGRLILDGNDVVRIVEHKDASEEERKNKLCFGGPMAVRAAHLPALLAKLTNKNAQGEFYMTDFVAHGRAAGLVCSAVFCLEADMQGVNSRADLAAAEATMQQRLRMAAMAGGVTMLDPSSVYLSMDTEFGEDVTVGQNVVFGPGCVIANGVTIKAFSHLEGAHVAEGAEIGPFARIRPGSEIGRKARIGNFVETKKARIEDGAKVNHLSYIGDARVGAGANIGAGTITCNYDGYNKFFTDIGAGAFIGSNSSLVAPVSIGDGAYLGSGSVVTKDVAADALGVARARQFEKPGWAAAFHAKHKDKKKASGE
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADE_SHEON
Sequence: MKAQILREMKVLKAIEPEFEVQRRVAFIKTKLKEARSKALVLGISGGVDSSTAGRLCQLAINSLNSEHPEGGYQFIAVRLPYQIQKDEHEAQQACQFIQPSKLVTVNVHQGVDGVHQATLSAFIDAGLTTPDAAKVDFIKGNVKARMRMIAQYELAGLVGGLVVGTDHSAENITGFYTKWGDGACDLAPLFGLNKRQVRQLAAYLGAPESLVYKAPTADLEDNKPLLEDEVALGLTYEQIDDFLEGKVVDKAVEEKLINIYKATQHKRQPIPTIYD
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: G6PI_MYCGA
Sequence: MIKLTFNLIKGLDYKKLDKNYQAKLDEIFSQLKNKKTPSANMLGWIDYVDQDHTKIYKSIDNKITEWDKLKVTDVVVIGIGGSFTGIKAILDVVAYLPSEQKRQIHFIRSLSENSFLKILEEVKDKNWGIVVISKSGTTLEPSVGFKLFREALYKQYGEQAQKRIVAITDPKKGVLHDIAVKNKYEMLPIYSDIGGRFSTITPSGLLVAGLVGADYKQLIEGAKKAKADLFASSELKKNSAYTYAALRHYLYTEMKKDVEIAITYEEQHEYLMLQHRQLFGESEGKSLNSLFPTYSVFTTDLHSMGQLYQDGKKIFFETVFSFEKANKNKLKLKNSEFNNDDQLDYLTKKSVNQLNYVACEATKQAHASAGVPIIEIDVKENSAYGFGYLYFWLCVATSVSALLLGHDPYNQPGVENYKQRMFKLL
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_SINMW
Sequence: MDLTVKTLEGKDAGKVSLSDAIFGLEPREDIIARVVRWQLAKRQQGTHKAKGRAEVSRTGAKMYKQKGTGRARHHSARAPQFRGGGKAHGPVVRSHAHDLPKKVRALGLRHALSAKLKAEEIIIVDDLVANEAKTKALAGAFASLGLTNALIIGGAEIEGNFKLAAQNIPNVDVLPVQGINVYDILRRGKLVLSKAAVEALEERFK
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: PSBD_ILLOL
Sequence: MTIALGRFTKEENDLFDIMDDWLRRDRFVFVGWSGLLLFPCAYFALGGWFTGTTFVTSWYTHGLASSYLEGCNFLTAAVSTPANSLAHSLLLLWGPEAQGDFTRWCQLGGLWTFVALHGAFGLIGFMLRQFELARSVQLRPYNAIAFSAPIAVFVSVFLIYPLGQSGWFFAPSFGVAAIFRFILFFQGFHNWTLNPFHMMGVAGVLGAALLCAIHGATVENTLFEDGDGANTFRAFNPTQAEETYSMVTANRFWSQIFGVAFSNKRWLHFFMLFVPVTGLWMSALGVVGLALNLRAYDFVSQEIRAAEDPEFETFYTKNILLNEGIRAWMAAQDQPHENLIFPEEVLPRGNAL
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.  D2 is needed for assembly of a stable PSII complex.
What are the official names of this protein?
Photosystem II D2 protein, PSII D2 protein, Photosystem Q(A) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: UNG_LACP3
Sequence: MKTLIHNDWQTVLEPVFESPEYAQLHAFLKEEYATKTIYPEMHHIFQAFEWTPFHDVKVVILGQDPYHNPRQAVGASFAVAPGVALPPSLQNIYKELQSDLGYPPVHHGYLKAWADQGVLLLNAVLTVQAGEAYSHQNHGWEELTDAAIAALSARGGVVFILWGNAAKKKAAVIDTSKNAIIASAHPSPLSASRGFFGSRPFSRTNAALEKMGEAPINWQLPETVKAD
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOH_BRUA2
Sequence: MEGIFAAYVLPALIIALKSVVLLVVLLIVVAYLLYADRKIWAAVQLRRGPNVVGPWGLFQAFADLLKFVFKEPIIPSGANKGVFLLAPFISAVLAMATWAVIPVNEGWAVANINVGILYIFAISSLEVYGVIMGGWASNSKYPFLGALRSAAQMVSYEVSIGFVIVTVLLTVGSLNLTDIVLSQNTGLGTMLGLPASFLDWNWLCLFPMFVVFFISALAETNRPPFDLVEAESELVAGHMIEYSSTPFLLFFLGEYVAITLMCALMTVLFLGGWLPPVDVWFLSWVPGIIWFMLKLCFCFFLFAMVKAFVPRYRYDQLMRLGWKVFLPISLFMVVATATFLKVFGLA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYTC_SULIM
Sequence: MESYKPVWLKGAVILAINLIDKGYKPVAVGLGERDFYIDVKSDTSITLDEVKKAINENVLANVPIENNQIVYKGNKVSIIEDKVSISTNLNPKYFEILNISTHHPNPNEQYVRIRGVAFETEEQLKDYLTWLEKAEETDHRLIGEKLDLFSFHEEAGSGLVLFHPKGQTIRNELIAFMREINDSMGYQEVYTSHVFKTDIWKISGHYTLYRDKLIVFNMEGDEYGVKPMNCPAHILIYKSKPRTYRDLPIRFSEFGHVYRWEKKGELYGLLRVRGFVQDDGHIFLREDQLREEIKMLISKTVEVWHKFGFKDDDIKPYLSTRPDESIGSDELWEKATNALISALQESGLKFGIKEKEGAFYGPKIDFEIRDSLGRWWQLSTIQVDFNLPERFKLEYIDKDGIKKRPVMVHRAIYGSIDRFVAILLEHFKGKLPTWLSSVQVRVLPITDEVNEYAEKVLNDMRKRRIRAEIDYAGETLSKRIKNAYDQGVPYILIVGKKEASEGTVTVRARGNIEVRNVKFEKFLELLITEIGQRDVEQTTVKALK
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also activates L-serine and transfers it to tRNA(Thr) but cannot deacylate incorrectly charged amino acid; unlike most archaea the editing function is found in a freestanding protein.
What are the official names of this protein?
Threonine--tRNA ligase catalytic subunit, Threonyl-tRNA synthetase catalytic subunit, ThrRS-cat.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14_STRCO
Sequence: MAKKSKIAKNEQRREIVARYAARRAELKEVLRRPSSTEAERLAAQRELRRQPRDASPTRVRNRDQIDGRPRGYLRVFGLSRVNLREQAHAGHLPGVRKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: HRCA_MYCA1
Sequence: MGSADERRFEVLRAIVADFIATKEPIGSKTLVERHNLGVSSATVRNDMAVLEAEGYITQPHTSSGRVPTEKGYREFVDRLDDVKPLSAAERRAIQNFLESGVDLDDVLRRAVRLLAQLTRQVAIVQYPTLSSSTVRHLEVIALTPARLLMVVITDSGRVDQRIVELGDVIDDHELSRLREMLGQALVGKKLSAASVAVADLAEQLRSPDGLGDAVGRSATVLLESLVEHSEERLLMGGTANLTRNAADFGGSLRSILEALEEQVVVLRLLAAQQEAGKVTVRIGYETAAEQMVGTSMVTTAYGTSDTVYGGMGVLGPTRMDYPGTIASVAAVAMYIGEVLGAR
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.