PharMolix/UniProtQA huggingface dataset:
Protein: MIAA_STUS1
Sequence: MSSLPPAIFLMGPTASGKTDLALELARVLPCELISVDSALVYRGMDIGTAKPSADVLAQFPHRLVDILDPAESYSAAEFSSDALAAMAEITAAGRIPLLVGGTMLYFKALQEGLADMPAADASVRAELEALAASEGLQVLHDRLAQVDPESAARIHPNDPQRLVRALEVYCVSGLTMSEHRARQRSQKAGPDAPGSGVLPYTVAQLCIAPAQRHILHERIERRFRHMVEQGFVEEVEALRSRGDLHLGMPSIRAVGYRQVWEYLDGSSTREEMVERGIIATRQLAKRQFTWLRSWGEVHWLDSLSCDNLPRALKYLQSLSILS
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: NRDR_NITWN
Sequence: MRCPSCNSLDTQVKDSRPTEDSAVIRRRRVCMACNFRFTTFERVQLRELTVIKRNGRRVPFDRDKLVRSLQISLRKRPVEPERIETMVSAIVRELESGGEAEISSETIGEIVMEHLRSLDDVAYVRFASVYRNFREAKDFEAVLGELSSEDDPRRVPLRK
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: NUOCD_PSEE4
Sequence: MTADNAIYIPPYKADDQDVVVELHNRFGADAFVAQETRTGMPVLWVKRAQLKEVLSFLRGVAKPYSMLYDLHGVDERLRTQRRGLPAADFSVFYHLLSVERNSDVMIKVSLSEGDLNLPTVTGIWPNANWYEREVWDMFGIDFAGHPHLSRIMMPPTWEGHPLRKDYPARATEFDPYSLTLAKQQLEEESARFNPEAWGMKRHGANEDYMFLNLGPNHPSAHGAFRIVLQLDGEEIVDCVPDIGYHHRGAEKMAERQSWHSFIPYTDRIDYLGGVMNNLPYVLAVEKLAGIQVPQKVDVIRIMLAEFFRITSHLLFLGTYIQDVGAMTPVFFTFTDRQRAYTVIEAITGFRLHPAWYRIGGVAHDLPRGWDKLVKDFVEWLPKRLDEYTKAALQNSILKGRTIGVAAYNTKEALEWGTTGAGLRATGCNFDLRKARPYSGYENFEFEVPLAHNGDAYDRCMVRVEEMRQSIRIIDQCLRNMPEGPYKADHPLTTPPPKERTLQHIETLITHFLQVSWGPVMPANESFQMIEATKGINSYYLTSDGGTMSYRTRIRTPSYPHLQQIPSVIKGSMVADLIAYLGSIDFVMADVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ADPPT_HUMAN
Sequence: MVFPAKRFCLVPSMEGVRWAFSCGTWLPSRAEWLLAVRSIQPEEKERIGQFVFARDAKAAMAGRLMIRKLVAEKLNIPWNHIRLQRTAKGKPVLAKDSSNPYPNFNFNISHQGDYAVLAAEPELQVGIDIMKTSFPGRGSIPEFFHIMKRKFTNKEWETIRSFKDEWTQLDMFYRNWALKESFIKAIGVGLGFELQRLEFDLSPLNLDIGQVYKETRLFLDGEEEKEWAFEESKIDEHHFVAVALRKPDGSRHQDVPSQDDSKPTQRQFTILNFNDLMSSAVPMTPEDPSFWDCFCFTEEIPIRNGTKS
What is the function of this protein?
Catalyzes the post-translational modification of target proteins by phosphopantetheine.  Can transfer the 4'-phosphopantetheine moiety from coenzyme A, regardless of whether the CoA is presented in the free thiol form or as an acetyl thioester, to a serine residue of a broad range of acceptors including the acyl carrier domain of FASN.
What are the official names of this protein?
L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase, 4'-phosphopantetheinyl transferase, Alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase, AASD-PPT, LYS5 ortholog.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: IL6_PIG
Sequence: MNSLSTSAFSPVAFSLGLLLVMATAFPTPERLEEDAKGDATSDKMLFTSPDKTEELIKYILGKISAMRKEMCEKYEKCENSKEVLAENNLNLPKMAEKDGCFQSGFNQETCLMRITTGLVEFQIYLDYLQKEYESNKGNVEAVQISTKALIQTLRQKGKNPDKATTPNPTTNAGLLDKLQSQNEWMKNTKIILILRSLEDFLQFSLRAIRIM
What is the function of this protein?
Acts as an essential factor in bone homeostasis and on vessels directly or indirectly by induction of VEGF, resulting in increased angiogenesis activity and vascular permeability.  Induces, through 'trans-signaling' and synergistically with IL1B and TNF, the production of VEGF.  Involved in metabolic controls, is discharged into the bloodstream after muscle contraction increasing lipolysis and improving insulin resistance (By similarity).  'Trans-signaling' in central nervous system also regulates energy and glucose homeostasis.  Mediates, through GLP-1, crosstalk between insulin-sensitive tissues, intestinal L cells and pancreatic islets to adapt to changes in insulin demand (By similarity).  Also acts as a myokine (By similarity).  Plays a protective role during liver injury, being required for maintenance of tissue regeneration (By similarity).  Also has a pivotal role in iron metabolism by regulating HAMP/hepcidin expression upon inflammation or bacterial infection (By similarity).  Through activation of IL6ST-YAP-NOTCH pathway, induces inflammation-induced epithelial regeneration (By similarity).
What are the official names of this protein?
Interleukin-6, IL-6.
What is the protein family that this protein belongs to?
Belongs to the IL-6 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: BTC_MOUSE
Sequence: MDPTAPGSSVSSLPLLLVLALGLAILHCVVADGNTTRTPETNGSLCGAPGENCTGTTPRQKVKTHFSRCPKQYKHYCIHGRCRFVVDEQTPSCICEKGYFGARCERVDLFYLQQDRGQILVVCLIVVMVVFIILVIGVCTCCHPLRKHRKKKKEEKMETLDKDKTPISEDIQETNIA
What is the function of this protein?
Growth factor that binds to EGFR, ERBB4 and other EGF receptor family members.  Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells.
What are the official names of this protein?
Probetacellulin.
What are the subcellular locations of this protein?
[Betacellulin]: Secreted, extracellular space. SUBCELLULAR LOCATION: [Probetacellulin]: Cell membrane; Single-pass type I membrane protein.
Protein: GLGC_YERPS
Sequence: MVRFESTDSLMLARQLPNKTVALILAGGRGSRLKDLTATRAKPAVHFGGKFRIIDFALSNCLNSGVRRIGVITQYQSHTLVQHIQRGWSFLNEEMNEFVDLLPAQQRLSTEQWYKGTADAVCQNLDIIRRYDAEYIVILAGDHIYKMDYSRMLLDHVEKGAECTVACIPVPISEGSEFGIMEVTADYQITAFYEKPANPPPIPGDPSNALASMGIYIFNADYLFKLLEEDNNTPGSSHDFGKDIIPQLTARKVVWAHPFDLSCVTSNAELPPYWRDVGTLDAYWRANLDLASVTPELDMYDRAWPIRTHMEPLPPAKFVQDRSGSHGMTMNSLVSGGCIVSGSVVVHSVLFPRVRVNSFCTIDSSLLLPDVHVGRSCRLRRCIIDRACHIPEGMVIGENANEDSARFYRSEGGVVLVTRDMLAKLEAK
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: CDC6C_HALMA
Sequence: MSDDPEDRMLGWDESVFRDEHVFEIDWLPETFKHRDTQMETLKYALRPAVRGSRPLNVIARGPPGTGKTTAVQILFDELTAQTDVKTVRVNCQMDSTRYAVFSRLFAEIFDYEPPSSGISFKKLFSQITDKLVEEDEVLVVALDDVNYLFYESEASDTLYSLLRAHEAHSGAKIGVICVSSDLELDTIDALDTRVQSVFRPEEVYFNPYGQAEIADILGERADRGFNEGVVGPTVLDRVAELTEEQGGDLRVGIDLLRRAGMNAEMRASRSVETEDVEAAYDKSKYVHLSRRLRELSDSETALVEVIAAHDGQQAGDIYDAFSEQTDLGYTRYSEIINKLDQLDIIDADYTNVEGRGRSRELTLNYDADAVLERL
What is the function of this protein?
Involved in regulation of DNA replication.
What are the official names of this protein?
ORC1-type DNA replication protein 3.
What is the protein family that this protein belongs to?
Belongs to the CDC6/cdc18 family.
Protein: DFA3_SYNY3
Sequence: MGIHAKLETVQLPLLVSCLFPPLTMPAKDVQICPIAVDTTVFRSRTWDRLKFEIEYGLQRGTTANSYLISADKIALFDPPGESFTDNFVGTLIQRLDLNSLDYVILGHVNANRAHTLKLLLSLAPQATIICSNPAAQNLEKLLADAEVNNPIQVMKGNDHLDLGRGHELTFIPTPSPRYPGQLCTYDPRTEILFTDKLFGAHVCGDQVFDEGWTIYQEDRRYYFDCLLAPAAAQVSAALNKLEAYPAQTYAPSHGPLVRYGLRELTRNYQQWLSEQQAQALNVALIYASAYGNTSTLAQAIARGITKAGVAVTAINAETSNAEEIKEAIGKSAGFIFGSPTLGGHAPTPIQTALGITLANASKTQLCGVFGSFGWSGEAIDMLENKFRDAGFSFGFDTIRVKFKPTDQTLKMCEEAGTDFAQALKKAEKRRQPKSALPESESARTEQALGRLVGSLCVVTAQQGELSSAMLASWVSQATFSPPGLTVAVAKERAIESLLHKNSCFVLNILQEGNHLGLMKHFLKPFAPGGDRFADVATETAENGAPILTESLAYLECRVQQRLECGDHWVLYAVTDRGALLKDGVTAVHHRKSGDHY
What is the function of this protein?
Mediates electron transfer from NADH to oxygen, reducing it to water.  This modular protein has 3 redox cofactors, in other organisms the same activity requires 2 or 3 proteins (By similarity).
What are the official names of this protein?
Putative diflavin flavoprotein A 3.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavodoxin reductase family.
Protein: PFA4_ASHGO
Sequence: MAVLVKWPWLGVAIPCFLISFTGYFAHFFVLTNFLSFKELLWFQVSLSMIWISYWKAIYKNPGRPTKGFRPLRYEWQNYCTKCETYKPERTHHCKRCNQCVLVMDHHCPWTMNCVGYKNFPHFIRFLFWIIATTGILLHYFVKRIKFTWVNRYATANLVSKQELIFLTILTPLDAFILLTISLLFVRCVKNQIVNGRTQIEAWEMDRIENLFYHQRLLPQLLTNLKEIYPGSLEGQEKEVEEFLSSSTCSFDEVINFPYDINPWVNLLNCMGSPLNWLNPFGGPKADGMVFQKNEISDYDEATSIQDKLLALPWPPDDTRHGIAFPSVSHVEKDTQGGEQVVRRRHVPIAVPPRNEWYNDWGESLEHFGVDVEVE
What is the function of this protein?
Mediates the reversible addition of palmitate to target proteins, thereby regulating their membrane association and biological function.
What are the official names of this protein?
Palmitoyltransferase PFA4, Protein S-acyltransferase, PAT, Protein fatty acyltransferase 4.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family. PFA4 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RRG8_KLULA
Sequence: MSKGWRKLFVSRGDGTKNSLKKTLKVPEVRSPLLTNFHRWAGKERVLKLTDKEQVTEAVGNSSWDLSKNLFANLLASPMRSDKASRFKFPRDLLIQMKLVQTGNENPGKLATLMPLINMKSGKSSSYVANSLKIFKGKKPGLGQLVPTAVNDSGIANISLSDIVLDKSLFTEKHQEELLQCIENCMTQLVDRRKSSVPVVVEDWDVVLTYDHNNDNDIELVRLKQLPKDPTVIILNLKVVENDSIRALINDKLKNHEVGVVLKFLKDERLIRLVYSLLNFSK
What is the function of this protein?
Required for respiratory activity and maintenance and expression of the mitochondrial genome.
What are the official names of this protein?
Required for respiratory growth protein 8, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RRG8 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CISY_NEUCR
Sequence: MAPVMRLGSAALRSSIHLTSRQTAFTAARCYSSKTQTLKERFAELLPENIEKIKALRKEHGSKVVDKVTLDQVYGGARGIKCLVWEGSVLDAEEGIRFRGKTIPECQELLPKAPGGKEPLPEGLFWLLLTGEVPSEQQVRDLSAEWAARSDVPKFIEELIDRCPSDLHPMAQLSLAVTALEHTSSFARAYAKGINKKEYWGYTFEDSMDLIAKLPTIAARIYQNVFKGGKVAAVQKDKDYSFNFANQLGFGDNKDFVELLRLYLTIHTDHEGGNVSAHTTHLVGSALSSPFLSVAAGLNGLAGPLHGLANQEVLNWLTEMKKVIGDDLSDEAITKYLWDTLNAGRVVPGYGHAVLRKTDPRYSAQRKFAQEHLPEDPMFQLVSQVYKIAPKVLTEHGKTKNPYPNVDAHSGVLLQHYGLTEANYYTVLFGVSRAIGVLPQLIIDRAVGAPIERPKSYSTDKWIEICKKL
What are the official names of this protein?
Citrate synthase, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: F16PA_BRUA1
Sequence: MTLVGNFSPLVLVGDSDRVEAETVGAYLDGWAGHDKVRLATANAIKAILSGAGRLVGRIARGYLPGDPGKLVGVNSDQDQQKSIDVGSHNLFVELLIAAGVASILSEEADLPVAGKADGLVAVAIDPLDGSGNVGLGAPLGTIFSIFPADVEEPFLQPGNRQIAAGYVSYGNSVDLGFSVGEGVIFATLDPVSGQFHITRRNVKLPERTSDLAFNASVQRHLSAGMQAYVNDAFLGKDGPRGRNFNMRWLGAAVGDMHRIMQRGGLFFYVNDSRPGYEKGRLRLVYEANPIAFLAREAGGKATDGSRPILDIVPQTYHERSALVFGVAEEVDILGEYFVK
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRE_ACIBT
Sequence: MTTPVSFHPQAFIELALSRGVLKFGEFTLKSGRVSPYFFNAGLLNDGEALSLLAQGYADKLTQCENVDVIFGPAYKGIPFVAATAVALSQVHNKSVPWGFNRKEAKDHGEGGVLVGAAVEGKKVWIIDDVITAGTAIREVVTILKNAGATIAGVLVALDRQERGQGELSAIQEVQKELEIPVHALITMKDLMDYLEAKGEKEALANMQAYREKYGI
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: PSRK_ARATH
Sequence: MRGELPNKHHSYTFFVFLFFFLILFPDLSISVNTLSATESLTISSNKTIVSPGGVFELGFFRILGDSWYLGIWYKKISQRTYVWVANRDTPLSNPIGILKISNANLVILDNSDTHVWSTNLTGAVRSSVVAELLDNGNFVLRGSKINESDEFLWQSFDFPTDTLLPQMKLGRDHKRGLNRFVTSWKSSFDPSSGSFMFKLETLGLPEFFGFTSFLEVYRSGPWDGLRFSGILEMQQWDDIIYNFTENREEVAYTFRVTDHNSYSRLTINTVGRLEGFTWEPTQQEWNMFWFMPKDTCDLYGICGPYAYCDMSTSPTCNCIKGFQPLSPQDWASGDVTGRCRRKTQLTCGEDRFFRLMNMKIPATTAAIVDKRIGLKECEEKCKTHCNCTAYANSDIRNGGSGCIIWIGEFRDIRNYAADGQDLFVRLAAAEFGERRTIRGKIIGLIIGISLMLVLSFIIYCFWKKKQKRARATAAPIGYRDRIQELIITNGVVMSSGRRLLGEEEDLELPLTEFETVVMATENFSDSNILGRGGFGIVYKGRLLDG
What is the function of this protein?
Truncated and inactivated form of SRK, the female specificity determinant of self-incompatibility when active.  Most A. thaliana cultivars contain such an inactive form and thus, are self-fertiles.
What are the official names of this protein?
Putative inactive G-type lectin S-receptor-like serine/threonine-protein kinase SRK, Pseudogene of S-locus receptor kinase A.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: GAG_HV2D2
Sequence: MGARGSVLSGKKTDELEKVRLRPGGKKKYMLKHVVWAVNELDRFGLAESLLESKEGCQKILKVLAPLVPTGSENLKSLFNIVCVIFCLHAEEKVKDTEEAKKIAQRHLAADTEKMPATNKPTAPPSGGNYPVQQLAGNYVHLPLSPRTLNAWVKLVEEKKFGAEVVPGFQALSEGCTPYDINQMLNCVGEHQAAMQIIREIINEEAADWDQQHPSPGPMPAGQLRDPRGSDIAGTTSTVEEQIQWMYRAQNPVPVGNIYRRWIQLGLQKCVRMYNPTNILDIKQGPKEPFQSYVDRFYKSLRAEQTDPAVKNWMTQTLLIQNANPDCKLVLKGLGMNPTLEEMLTACQGIGGPGQKARLMAEALKEALTPAPIPFAAVQQKAGKRGTVTCWNCGKQGHTARQCRAPRRQGCWKCGKTGHIMSKCPERQAGFLGLGPWGKKPRNFPMTQVPQGVTPSAPPMNPAEGMTPRGATPSAPPADPAVEMLKSYMQMGRQQRESRERPYKEVTEDLLHLNSLFGEDQ
What is the function of this protein?
Plays a role in budding of the assembled particle by interacting with the host class E VPS proteins TSG101 and PDCD6IP/AIP1.
What are the official names of this protein?
Gag polyprotein, Pr55Gag.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group gag polyprotein family.
What are the subcellular locations of this protein?
[Gag polyprotein]: Host cell membrane; Lipid-anchor. Host endosome, host multivesicular body. Note=These locations are probably linked to virus assembly sites. The main location is the cell membrane, but under some circumstances, late endosomal compartments can serve as productive sites for virion assembly. SUBCELLULAR LOCATION: [Matrix protein p17]: Virion membrane; Lipid-anchor. Host nucleus. Host cytoplasm. SUBCELLULAR LOCATION: [Capsid protein p24]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p7]: Virion.
Protein: UBIE_PARP8
Sequence: MTQTHFGYQTVDEQEKAKKVAGVFHSVASNYDLMNDLMSGGLHRAWKAFTIAQANVRPGYKVLDIAGGTGDLSKAFAKRAGETGEVWHTDINESMLRVGRDRLIDKGVITPTLLCDAEKIPFPDNYFDVVTVAFGLRNMTHKDAALAEMRRVLKPAGRLLVLEFSKVWDPLKKAYDVYSFKVLPWLGDRFAKDADSYRYLAESIRMHPDQETLKTMMEQAGLDAVKYYNLSAGVVALHVGTKY
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: NU4LM_AILFU
Sequence: MSMVYINIFLAFAISFVGLLMYRSHLMSSLLCLEGMMLSLFVMLTITILSNHFTLASMIPIILLVFAACEAALGLSLLVMVSNTYGTDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TRPD_CALS4
Sequence: MLQEAIKKIVLKENLDEKEAYEVMGEIMSGNGTPSLIGGLLIGLRLKGESVEEITGFAKAMRDNAVKLQLDADYVIDTCGTGGDGGKTFNISTAVAIIASAAGVKVAKHGNRAVSSKSGSADVLRELGFNIEAEPMYTKKMIEEKGMGFLFAPLYHRAMKNVLPIRRELGTRTVFNLLGPLTNPAPIKGQVLGVYDRNLTHPIAEVLLKLGIERAMVVHGFDGLDEITTTAPTYVSEVKEGEIFDYVIDPLDFDIPYSKPEDLKGKGPRENAEIIIDILKGQKGPRRDIVVLNTAAALYVGKLVENLKEGVELAERLLNSGLAYERFLEILGYQRRIIS
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: KDSA_PARP8
Sequence: MKLGDFEIGLDKPFFLIAGTCVVESEQMTIDTAGKLKEICAKLKIPFIYKSSYDKANRSSGKSFRGLGMDEGLRILSEVKRQLGLHVLTDVHSEHEIEPVASVVDVLQTPAFLCRQTDFIHACARSGKPVNIKKGQFLAPHDMKNVIDKARDAAREAGLSEDRFMACERGVSFGYNNLVSDMRSLAIMRETGAPVVFDATHSVQLPGGQGTSSGGQREFVPVLARAAVATGIAGLFMETHPNPAEAKSDGPNAVPLHRMADLLETLMTLDQAVKRTPFLENDFN
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH10_CALS8
Sequence: MKIRPIGDRILIKFKEREEVTKSGIVLPDTVKEKPQIAEVIEVGPGGIVDGEKVEMVVKKGDKVIVSKYAGTEIKIDGEEYTIIRQDDVLAIIED
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_CARHZ
Sequence: MLKFLKNLLDDNAREIKRLTARVEEINSLEPQMQKLSDEELRAKTGEFKERIARGESLDELLPEAFAVVREASRRVLGMRHFDVQLMGGIVLHEGKIAEMKTGEGKTLVATLPAYLNALTGRGVHIVTVNDYLARRDAEWMGKIYKFLGLSVGLVVHGMDYAEKKAAYLADITYGTNNEFGFDYLRDNMAIHPDQVVQRELYYAIIDEVDSILIDEARTPLIISGEAEKSTDLYYTFAKIVKQLVPGEDYTVDEKAHAVMPTEAGIHKVEKMLGIQNLYADEHMELTHHLNAALKAQALMKRDRDYVVKDGQVIIVDEFTGRLMFGRRYSDGLHQAIEAKEGVKIEQETQTLATITFQNYFRMYEKLAGMTGTAETEENEFRKIYNLSVVVIPTHKPMIRKDLPDVIFKTEKAKFKAIVEEVARRHQTGQPILIGTISIEKSEMLSEMLKKRGIPHQVLNAKYHEKEAEIVAQAGRLGAVTIATNMAGRGTDILLGGNPEFLALQELRKMGKTPEDDPELYRELLAKYKKITDEEHKKVVELGGLHIIGTERHESRRIDNQLRGRAGRQGDPGSSQFFISLEDDLMRLFGSDNIAGLMDRLGLDEDTPIEHPLITRSIETAQKRVENRNFEIRKHVLEYDNVMNQQRELIYSQRRRVLFGEDVLTFVHQMIEAVVERAVDTYCPDGVHPEEWDLKGLLEYAHNVFLPNHQLTPEDLADTGKKALVEFLVEKAKEYYKKREEELGGEQLRELERYVILRVVDEKWMDHLDAMDQLREGIGLRAYGQKDPLVEYKIESVEMFNNMIAAIQEDVVRYLMRLSVVRQPETRRVRRVVENRYQEEGPKKPYRREQKIGRNDPCPCGSGKKYKKCCGRNG
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: Y5161_DICDI
Sequence: MLNRNQKYDLHTIILNSKSLRKHHIKEEDVIHLKGDVKEHFYELKIVKEAHNMAFKKCTVEEGLQLRDLFNGEGNIFTTSFHINEDKSELSQLFIDNCIEKGVSAVPHLVYNGASSLLTIDVNGEEYEISRKRLNGLSNYIKSVYSTGDLLEPQDHIFGKIHPSRTFQRTLKKYYMFMKRISELLDN
What are the official names of this protein?
Uncharacterized protein DDB_G0275161.
Protein: LSPA_ALTMD
Sequence: MLKLFRETGLRFLWISALAFILDQWSKYTVIDTMSLYQSIQVLPFFNFTYVHNYGAAFSFLENAGGWQRWFFTAIAVVVSVVILWWLKQSPRSQKMLPVAFAFILGGALGNVYDRLVHGYVIDFLDFYVNNYHWPAFNIADSAIFIGAALLIIDMFKNGDKKSEENGAESKAGSANSSETIK
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NLGN3_RAT
Sequence: MWLQLGLPSLSLSPTPTVGRSLCLILWFLSLVLRASTQAPAPTVNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVYVPTEDVKRISKECARKPNKKICRKGGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGNMIDGSVLASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFYHHCQSLMKPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHLVPHLYNLHDMFHYTSTTTKVPPPDTTHSSHITRRPNGKTWSTKRPAISPAYSNENAPGSWNGDQDAGPLLVENPRDYSTELSVTIAVGASLLFLNVLAFAALYYRKDKRRQEPLRQPSPQRGTGAPELGTAPEEELAALQLGPTHHECEAGPPHDTLRLTALPDYTLTLRRSPDDIPLMTPNTITMIPNSLVGLQTLHPYNTFAAGFNSTGLPNSHSTTRV
What is the function of this protein?
Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members.  Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins.  May promote the initial formation of synapses, but is not essential for this.  May also play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system.
What are the official names of this protein?
Neuroligin-3, Gliotactin homolog.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Synapse. Note=Detected at both glutamatergic and GABAergic synapses.