PharMolix/UniProtQA huggingface dataset:
Protein: PERL_BUBBU
Sequence: MWVCLQLPVFLASVTLFEVAASDTIAQAASTTTISDAVSKVKIQVNKAFLDSRTRLKTTLSSEAPTTQQLSEYFKHAKGQTRTAIRNGQVWEESFKRLRRDTTLTNVTDPSLDLTALSWEVGCGAPVPLVKCDENSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLALPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSNEHSKTQCEEYCIQGDNCFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLAREQINAVTSFLDASLVYGSEPSLASRLRNLSSPLGLMAVNQEAWDHGLAYLPFNNKKPSPCEFINTTARVPCFLAGDFRASEQILLATAHTLLLREHNRLARELKKLNPHWNGEKLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLTRGLLAKKSKLMNQDKMVTSELRNKLFQPTHKIHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQTVLKNKILAKKLMDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKFSFSRLICDNTHITKVPLHAFQANNYPHDFVDCSTVDKLDLSPWASREN
What is the function of this protein?
Heme-containing oxidoreductase which catalyzes the conversion of thiocyanate (SCN(-)) into antimicrobial agent hypothiocyanous acid (OSCN(-)) in the presence of hydrogen peroxide (H2O2) (Probable).  Also involved in the conversion of iodide (I(-)) into hypoiodite (IO(-)) in the presence of H2O2 (By similarity).  Responsible for the inactivation of a wide range of micro-organisms and hence, important component of defense mechanism (PubMed:12071645).  Shows antibacterial properties against E. coli, K. pneumoniae, P. aeruginosa, S. sonnei, S. saphrophyticus, S. epidermidis and S. dysenteriae (PubMed:12071645).  May protect the udder from infection and may promote growth in newborns (By similarity).  May be implicated in airway host defense against infection (By similarity).  May contribute to maintaining an appropriate H2O2 cellular level, therefore protecting cells from H2O2-caused injuries and inflammation (By similarity).
What are the official names of this protein?
Lactoperoxidase, LPO, WBLP.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. XPO subfamily.
What are the subcellular locations of this protein?
Secreted. Cytoplasm.
Protein: GLYAT_BOVIN
Sequence: MFLLQGAQMLQMLEKSLRKSLPMSLKVYGTVMHMNHGNPFNLKALVDKWPDFQTVVIRPQEQDMKDDLDHYTNTYHVYSEDLKNCQEFLDLPEVINWKQHLQIQSTQSSLNEVIQNLAATKSFKVKRSKNILYMASETIKELTPSLLDVKNLPVGDGKPKAIDPEMFKLSSVDPSHAAVVNRFWLFGGNERSLRFIERCIQSFPNFCLLGTEGTPVSWSLMDQTGEMRMAGTLPEYRAQGLVTHAIYQQAQCLLKRGFPVYSHVDPKNQIMQKMSQSLNHVPMPSDWNQWNCEPL
What is the function of this protein?
Mitochondrial acyltransferase which transfers an acyl group to the N-terminus of glycine and glutamine, although much less efficiently.  Can conjugate a multitude of substrates to form a variety of N-acylglycines, thereby detoxify xenobiotics, such as benzoic acid or salicylic acid, and endogenous organic acids, such as isovaleric acid.
What are the official names of this protein?
Glycine N-acyltransferase, Acyl-CoA:glycine N-acyltransferase, AAc, Aralkyl acyl-CoA N-acyltransferase, Aralkyl acyl-CoA:amino acid N-acyltransferase, Benzoyl-coenzyme A:glycine N-acyltransferase, Glycine N-benzoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycine N-acyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: KGUA_STRA5
Sequence: MSERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFDYSVSMTTRPQRPGEVDGVDYFFRTREEFEALIKEGQMLEYAEYVGNYYGTPLSYVNETLDKGIDVFLEIEVQGALQVKSKVPDGVFIFLTPPDLEELEERLVGRGTDSPEVIAQRIERAKEEIALMREYDYAVVNDQVSLAAERVKRVIEAEHYRVDRVIGRYTNMVKETDKKLS
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSIC_SHISS
Sequence: MLNYVIKRLLGLIPTLFIVSVLVFLFVHMLPGDPARLIAGLEADAQVIELVRQQLGLDQPLYHQFWHYISNAVQGDFGLSMVSRRPVADEIASRFMPTLWLTITSMVWAVIFGMAAGIIAAVWRNRWPDRLSMTIAVSGISFPAFALGMLLIQVFSVELGWLPTVGADSWQHYILPSLTLGAAVAAVMARFTRASFVDVLSEDYMRTARAKGVSETWVVLKHGLRNAMIPVVTMMGLQFGFLLGGSIVVEKVFNWPGLGRLLVDSVEMRDYPVIQAEILLFSLEFILINLVVDVLYAAINPAIRYK
What is the function of this protein?
Part of the ABC transporter complex GsiABCD involved in glutathione import.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Glutathione transport system permease protein GsiC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SAL2B_ONCMY
Sequence: AGFVLKGYTKTSQ
What is the function of this protein?
Antibacterial activity against Gram-negative bacteria.
What are the official names of this protein?
Salmocidin-2B.
What are the subcellular locations of this protein?
Secreted.
Protein: CA122_CONBU
Sequence: SDRASDGRNAAANDRASDLVALTVRGCCTYPPCAVLSPLCD
What are the official names of this protein?
Conotoxin Bu22.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL19_FRATW
Sequence: MKNKFVELVEKSQLRTDLPEFNPGDSITVNLWIKEGDKQRIQAFKGFVLRKRNRGLHSAFTVRKMSSGVGVERTFQTHSPLIDSIIVEKRADVRRAKLYYMRGLTGKAARIKEKV
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: LAT3_HUMAN
Sequence: MAPTLQQAYRRRWWMACTAVLENLFFSAVLLGWGSLLIILKNEGFYSSTCPAESSTNTTQDEQRRWPGCDQQDEMLNLGFTIGSFVLSATTLPLGILMDRFGPRPVRLVGSACFTASCTLMALASRDVEALSPLIFLALSLNGFGGICLTFTSLTLPNMFGNLRSTLMALMIGSYASSAITFPGIKLIYDAGVAFVVIMFTWSGLACLIFLNCTLNWPIEAFPAPEEVNYTKKIKLSGLALDHKVTGDLFYTHVTTMGQRLSQKAPSLEDGSDAFMSPQDVRGTSENLPERSVPLRKSLCSPTFLWSLLTMGMTQLRIIFYMAAVNKMLEYLVTGGQEHETNEQQQKVAETVGFYSSVFGAMQLLCLLTCPLIGYIMDWRIKDCVDAPTQGTVLGDARDGVATKSIRPRYCKIQKLTNAISAFTLTNLLLVGFGITCLINNLHLQFVTFVLHTIVRGFFHSACGSLYAAVFPSNHFGTLTGLQSLISAVFALLQQPLFMAMVGPLKGEPFWVNLGLLLFSLLGFLLPSYLFYYRARLQQEYAANGMGPLKVLSGSEVTA
What is the function of this protein?
Uniport that mediates the transport of neutral amino acids such as L-leucine, L-isoleucine, L-valine, and L-phenylalanine (PubMed:12930836).  The transport activity is sodium ions-independent, electroneutral and mediated by a facilitated diffusion (PubMed:12930836).
What are the official names of this protein?
Large neutral amino acids transporter small subunit 3, L-type amino acid transporter 3, Prostate cancer overexpressed gene 1 protein, Solute carrier family 43 member 1.
What is the protein family that this protein belongs to?
Belongs to the SLC43A transporter (TC 2.A.1.44) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RN146_SALSA
Sequence: MASCGEVDHSVSSLPSSKKGSGDSACSGSSGSSPALPVPECAICLQSCVHPVQLPCRHVFCFLCVKGASWQSKRCALCRQEVPEDFLEHPTLLSPEELKTGGRGATGDNAWYYEGRNGWWQYDERTSRELEDAFSKGKKTAEMLIAGFLYVADLENMVQYRRNEHGRRRKIKRDVVDIPKKGVAGLRLDTEGGVQGSAAAGRGNSADGADTSAAAVQQAAAAPAATTVLSAPARPPTSLGGQPGSPTSPSLEDTLALLHISPTDAPERAEVGEGEEEATATPSMSSSPNTYADGSGDWSDDEGDGEAVEPREQRLRLGESLVDRSPPGAEASSSSSVRSRRPDGQCTEV
What is the function of this protein?
E3 ubiquitin-protein ligase that specifically binds poly-ADP-ribosylated proteins and mediates their ubiquitination and subsequent degradation.  May regulate many important biological processes, such as cell survival and DNA damage response.  Acts as an activator of the Wnt signaling pathway by mediating the ubiquitination of poly-ADP-ribosylated proteins.  Neuroprotective protein.  Protects against cell death induced by DNA damaging agents and rescues cells from G1 arrest.  Promotes cell survival after gamma-irradiation.  Facilitates DNA repair.
What are the official names of this protein?
E3 ubiquitin-protein ligase rnf146, RING finger protein 146, RING-type E3 ubiquitin transferase rnf146.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Note=Translocates to the nucleus after DNA damage.
Protein: Y1326_STAES
Sequence: MDNKDNRKFYLIREDVLPESVIKTLKVKDALKNNSNLSIYDAVKQFNLSRSAFYKYRETIFPVDEKILDQREFTLILYVNDIVGMLAQVLNAISQLQLSVLTIHQSVPIEDKATITLSLNARNSNLSIDEVIESLREINHVTKVDLISMTM
What are the official names of this protein?
UPF0735 ACT domain-containing protein SE_1326.
What is the protein family that this protein belongs to?
Belongs to the UPF0735 family.
Protein: EPA4B_XENLA
Sequence: MAGIVHGILFCGLFGLCWAVTGSRIYPASEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMESSQNNWLRTDWIPRSGAQRVYVEIKFTLRDCNSLPGVMGTCKETFNLYYYESNNDKERFIRETQYVKIDTIAADESFTQVDIGDRIMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKKCPLTVRNLAQFPDTITGSDTSSLVEVRGSCVDNSEEKDVPKMYCGADGEWLVPIGNCLCNAGFEEHNGGCQACKVGYYKALSTDAACSKCPPHSYALREGSTSCTCDRGYFRADTDPASMPCTRPPSAPQNLISNVNETSVNLEWSPPQNSGGRPDVSYNLVCKRCGSDLTRCSPCGSGVHYSPQQNGLKTTKVSINDLQAHTNYTFEVWAINGVSKQNPEQDQAVSVTVTTNQAAPSTVTQIQPKEITRHSVSLTWPEPERANGVILEYEVKYYEKDQNERSYRIVKTASRSADIKGLNPLTGYVFHVRARTAAGYGEFSGPFEFTTNTVPSPMIGEGTSPTVLLVSVAGSIVLVVILIAAFVISRRRSKYSKAKQEADEEKHLNQGVKTYVDPFTYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREIYVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKDRSDRPKFGQIVSMLDKLIRNPNSLKRTGLENSRTNTALLDPSSPEWSQVASVLDWLQASKWKRYKDNFTAAGYTSLEAVVHVNQDDLTRIGISSPSHQNKILSSVQGMRTQLQQMQGRMVPV
What is the function of this protein?
Receptor tyrosine kinase which binds membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.  The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling.  Highly promiscuous, it has the unique property among Eph receptors to bind and to be physiologically activated by both GPI-anchored ephrin-A and transmembrane ephrin-B ligands including EFNA1 and EFNB3.  Upon activation by ephrin ligands, modulates cell morphology and integrin-dependent cell adhesion through regulation of the Rac, Rap and Rho GTPases activity.  Plays an important role in the development of the nervous system controlling different steps of axonal guidance including the establishment of the corticospinal projections (By similarity).
What are the official names of this protein?
Ephrin type-A receptor 4-B, Pagliaccio, Tyrosine-protein kinase receptor PAG.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Early endosome. Note=Clustered upon activation and targeted to early endosome.
Protein: LOLD2_RHOBA
Sequence: MHSSPELLLEARGIRKSYHKDKIELPILRGIDVGFVTGEMSALVGRSGSGKSTLMHLLATLDQPDSGEVWFDGTRIDNQSRARRDQYRNSQIGIIFQFYHLLPELSAIENVLAPAMIRRSVLGYLRDRKSLRLRAEAMLDRVGLLTRSHHQPSEMSGGEMQRVAIARSLMSNPKLLLADEPTGNLDTETGATILSLLRELNREDELTIVMITHDDSIAETADRCYRMCDGLLEDNASNLAGGDRSDSAKLETVAA
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DHR18_ARATH
Sequence: MASYQNRPGGQATDEYGNPIQQQYDEYGNPMGGGGYGTGGGGGATGGQGYGTGGQGYGSGGQGYGTGGQGYGTGTGTEGFGTGGGARHHGQEQLHKESGGGLGGMLHRSGSGSSSSSEDDGQGGRRKKGITQKIKEKLPGHHDQSGQAQAMGGMGSGYDAGGYGGEHHEKKGMMDKIKEKLPGGGR
What are the official names of this protein?
Dehydrin Rab18.
What is the protein family that this protein belongs to?
Belongs to the plant dehydrin family.
Protein: FAEB2_ASPFC
Sequence: MTKLSLLPLLTLASAVLAKQDAFQAKCASFGRKIKLPNVHVNFVEYVPGGTNLTLPDNDVTCGASSQVVSADMCRVAMAVDTSKSSQITLEAWFPREYTGRFLSTGNGGLSGCIQYYDLAYTAGLGFATVGANNGHNGTSGKPFYQHPEVIEDFAYRSIHTGVVVGKQLTKMFYKEGFDKSYYLGCSTGGRQGFKSIQKYPNDFDGVVAGAPAFNFVNLISWSIHFYSITGSNTSDTYLSPESWKVVHDEIVRQCDEIDGAKDGIIEDTDLCQPVIETIICKPGASDKTNCITGAQAKTVRNVLSPFYGVNGTLLYPRMQPGSELFASSVVYNGQPFRYSTDWYRYVVYNNPDWDATKWTVEDAAVALAQNPYNIQTWDADISSFQKAGGKVLTYHGMQDQLISSDNSKLYYARVAEEMGLGPEELDDFYRFFPVSGMAHCTGGDGAYGIGNGLRTYNGAEPENNVLMAMVQWVEKGIAPEFIRGAKFSNGVGSSVEYTRKHCRYPRRNVYKGPGNYSDENAWECV
What is the function of this protein?
Involved in degradation of plant cell walls.  Hydrolyzes the feruloyl-arabinose ester bond in arabinoxylans as well as the feruloyl-galactose and feruloyl-arabinose ester bonds in pectin.
What are the official names of this protein?
Probable feruloyl esterase B-2, Ferulic acid esterase B-2, FAEB-2.
What is the protein family that this protein belongs to?
Belongs to the tannase family.
What are the subcellular locations of this protein?
Secreted.
Protein: DEFL_AGRFC
Sequence: MAIRPILPYPHAGLSGICAPVTVFDDHLRELVTDLIDTMRAAPGVGITAAHIGVLQRVFVLELTPGTILTYINPEITSHSPQTMRHVEGSVSMPGFTDEVERPSTVEVRFQDITGAEQTETAEGFHAICIQHEIDQLDGIFWLKRLSRLKRDRLVKKWEKSRNP
What are the official names of this protein?
Peptide deformylase-like, Polypeptide deformylase-like.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: DMS5_PHYTS
Sequence: GLWSKIKEAAKTAGKAAMGFVNEMV
What is the function of this protein?
Antimicrobial peptide, active against the Gram-positive bacterium S. aureus, the Gram-negative bacteria E. coli and P. aeruginosa, and the yeasts C. albicans and P. brasiliensis.  Has hemolytic activity (15% hemolysis at 128 ug/ml).
What are the official names of this protein?
Dermaseptin-5, DStar 05.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Dermaseptin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: FA98A_HUMAN
Sequence: MECDLMETDILESLEDLGYKGPLLEDGALSQAVSAGASSPEFTKLCAWLVSELRVLCKLEENVQATNSPSEAEEFQLEVSGLLGEMNCPYLSLTSGDVTKRLLIQKNCLLLLTYLISELEAARMLCVNAPPKKAQEGGGSEVFQELKGICIALGMSKPPANITMFQFFSGIEKKLKETLAKVPPNHVGKPLLKKPMGPAHWEKIEAINQAIANEYEVRRKLLIKRLDVTVQSFGWSDRAKSQTEKLAKVYQPKRSVLSPKTTISVAHLLAARQDLSKILRTSSGSIREKTACAINKVLMGRVPDRGGRPNEIEPPPPEMPPWQKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGGYDHGGRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGGQFEQHFQHGGYQYNHSGFGQGRHYTS
What is the function of this protein?
Positively stimulates PRMT1-induced protein arginine methylation (PubMed:28040436).  Involved in skeletal homeostasis (By similarity).  Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts (By similarity).
What are the official names of this protein?
Protein FAM98A.
What is the protein family that this protein belongs to?
Belongs to the FAM98 family.
Protein: TIG_NEIMB
Sequence: MMSVTVETLENLERKVVLSLPWSEINAETDKKLKQTQRRAKIDGFRPGKAPLKMIAQMYGASAQNDVINELVQRRFYDVAVAQELKVAGFPRFEGVEEQDDKESFKVAAIFEVFPEVVIGDLSAQEVEKVTASVGDAEVDQTVEILRKQRTRFNHVEREARNGDRVIIDFEGKIDGEPFAGGASKNYAFVLGASQMLPEFEAGVVGMKAGESKDVTVNFPEDYHGKDVAGKTAVFTITLNNVSEATLPEVDADFAKALGIADGDVAKMREEVQKNVSREVERRVNEQTKESVMNALLKAVELKAPVALVNEEAARLANEMKQNFVNQGMADAANLDLPLDMFKEQAERRVSLGLILAKLVDENKLEPTEEQIKAVVANFAESYEDPQEVIDWYYADPSRLQAPTSLAVESNVVDFVLGKAKVNEKALSFDEVMGAQA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase (By similarity).
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: RL2_BIFA0
Sequence: MAIRVYKPTTPGRRNASVSDFSDLTRSTPEKSLIRKNSKTGGRNNYGRMTSRHRGGGHKRQYRLIDFRRWDKDGVPATVAQIEYDPNRSARIALLHYADGEKRYIIAPEGIKQGDRIETGANADIKPGNNLPLRNIPTGTVVHAIELRPLGGAKIARSAGAAVQLVAKDGAYAQLRMPSGEIRNVDARCRATVGEVGNSDHANIQLGKAGRARWMGKRPITRGESMNPVDHPHGGRTRGGKPPVSPWGKGEVRTRRPKKASNKMIVRRRPNGKNRK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RS13_MYXXD
Sequence: MARIAGIDLPPNKRAVISLQYIYGIGNKSAQDIIAAAGIDPTTRTKDLTEEQARKIREIIEASYKVEGDLRREVTMNIKRLMDLGCYRGLRHRKGLPVRGQRTHTNARTRKGPKRGIVRAKPAAPAR
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: KDPA_SERP5
Sequence: MAASAFLLIASFMLVLLLLARPLGSFLARLIEGEPLPALRRVEAAVWRCCGNTTAEMNWWQYALAILWFNLLGLALLFALLMTQGSLPLNPQGFPGLSWDLAFNTAVSFVTNTNWQAYSGESTLSYLSQMAGLAVQNFLSAATGIAVAFALIRAFTRRSSATIGNAWIDVFRITLYVLLPISLLIALFFVSQGTLQNFLPYLHISTLEGAQQTLPMGPVASQEAIKMLGTNGGGFFGVNSAHPFENPTVLTNFVQMLAIFLIPCALCFSFGQVAGENRQGHALIWAMSLIFVVAVVVVMYAELAGNPHLSELGSASNINMEGKESRFGILATSMFSVVTTAASCGAVNAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMLLFVLLTVFIAGLMIGRTPEYLGKKIDVYDMKMTALAILVTPTLVLLGSALAISTDVGRAGILNPGAHGFSEVLYALSSAANNNGSAFGGLSVNTPFYNLLLAFAMFVGRFGVILPVLAIAGSLCAKKRQPAGNGTLPTYGPLFIGLLVGTVLLVGALTFVPALALGPVAEHLQLWLTK
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUSB_BACCR
Sequence: MKRRTARERAMQALYQMDITGELEPKVAVENTLDEGEETNEFLESLVVGFVENKEAIDEAIRQNLKKWKLERISIVDRSILRVAVYEMKYMEEIPHNVTINEAIEIAKTFGDEESRRFINGVLSNIKDTL
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: RL6_CORJK
Sequence: MSRVGKAPVAVPSGVTININGQSVEVKGPKGTLSQDIPAPITVAQEGEELVVSRPDDHRKNRSLHGLSRSLVFNMIEGVTKGYTINMEIFGVGYRVQLKGKNLEFALGYSHPVLIEAPEGITFAVDGNTKFSIAGIDKQQVGQIAANIRRLRKDDPYKGKGIRYEGEQVRRKVGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: SURA_XANCP
Sequence: MTKPFSVLLASLLVITSTVSPLASAQQSQPLDRIAAIVDEDVVLQSELDRAVRNVKSQYAGRDNQLPPDDVLQRQVLERLVLVKLQVGRAEGSGIRVSDEELNRAIASIAQQNGTSVDGLRQKLAADGMGYADFRASVRDEIIVQRLRQSFAQSRISVSEGEVDTALAQQATTGSQYHLAHILVGLPEGATAEQIATGQKKVDGVKALIDKGELDFSAAAVRYSDSPNALEGGDLGWRSLDEIPNAFAQLIRDMQPGQVAGPLRGPSGFQLLKLVEMRDANAGGEKKVLTEYNARHILVRIGDNQTEAQAKAKIDTLRARIVGGADFQATAKESSEDTNSRGQGGDLGWFPADAFGPDFGKQVEGLTDGAVSEPFRTQAGWHIVQRVGTRQTDVSAENQRAQIRETIGRRKLEEEYNRYLQELRGEAFVSFRTGDRADADATAAPEPAAAPAAPTPPPAQPTR
What is the function of this protein?
Chaperone involved in the correct folding and assembly of outer membrane proteins.  Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins.  May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
What are the official names of this protein?
Chaperone SurA, Peptidyl-prolyl cis-trans isomerase SurA, PPIase SurA, Rotamase SurA.
What are the subcellular locations of this protein?
Periplasm. Note=Is capable of associating with the outer membrane.
Protein: SYE_BUCAI
Sequence: MKVKTRFAPSPTGNLHIGSIRTALYSWLFARHHNGKFVLRIEDTDLVRSELISIDSIFNGLKWLGLNWDEGPYFQTKRLDRYKEVINVMLEKEDAYICVCSCQELEEIRKKQIEKGNKPRYPGTCRNLNIKNISNQNHVIRFKNPLFGKVKFQDKIRGEIVFDNAELDDLVIQRSNGMPTYNFCVVVDDMDMKITHVIRGEDHISNTPRQINILNSLKVKIPVYAHLSMILDEKGNKISKRKNAINIIEYYENGFLPEALLNYIIRLGWSYGDKEIFNLSEMKELFNLKSITKSSSTVNFKKLLWMNKYYINNSPLDYVSDCLKNYMEKKNINVEKGPDLELLVKLFRSRHHTLKEITESCRYFYEEINFFNHTVIEKYFTRKNCFILQTCYKKIEKLSIWDNKNISKIINDVSELIKVTKKEISMILRISMTGDICSPSISTVILLIGKEKALLRINNVVNYIKNL
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HDA_SALHS
Sequence: MSSWVEVSLNTPAQLSLPLYLPDDETFASFWPGDNASLLAALQNVLRQEHSGYIYLWAREGAGRSHLLHAACAELSQRGDAVGYVPLDKRTWFVPEVLDGMEHLSLVCIDNIECVAGDELWEMAIFDLYNRILESGKTRLLITGDRPPRQLNLGLPDLASRLDWGQIYKLQPLSDEDKLQALQLRARLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDHASITAQRKLTIPFVKEILKL
What is the function of this protein?
Mediates the interaction of DNA replication initiator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN).  Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinitiation, a process called regulatory inhibition of DnaA or RIDA (By similarity).
What are the official names of this protein?
DnaA regulatory inactivator Hda.
What is the protein family that this protein belongs to?
Belongs to the DnaA family. HdA subfamily.
Protein: GPA3_USTMA
Sequence: MGNCLSSSDQKEAKDRSVAIDKQIEEDSRKFKKECKILLLGSGESGKSTIVKQMKIIHQNGYTKDELLLYRLTVIKNLVDSAQAMVLALRKFKMEPEMPENRENVDAILQYRVDADPGATLDHAMARKVDSLWKDPIVPAIMERSSEFYLMDSAAYFFDNVNRIGQSDYVPNENDVLRARSKTTGISETRFNMGQLSIHLFDVGGQRSERKKWIHCFEAVTSIIFCVALSEYDQVLLEESGQNRMAESLVLFESVVNSRWFLRTSVILFLNKIDIFKQKIPKQPLSKYFPEYSGGPDINKAAKYILWRFTQTNRARLSIYPHLTQATDTSNIRLVFAAVKETILTNALKDSGIL
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.  GPA3 plays an active role in transmission of the pheromone signal.
What are the official names of this protein?
Guanine nucleotide-binding protein alpha-3 subunit.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family.