PharMolix/UniProtQA huggingface dataset:
Protein: HIS4_BACC1
Sequence: MEIFPAIDLKKGRCVRLYQGEFSKETVMNEDPVAQAIIFETFGAKRLHIVDLDGAVAGESLNLSVIERICKAVRIPVQVGGGIRSLVAVEKLFSVGVDKVILGTAALYDKPFLEEAVFLYKEKIIVGIDAKNGFVATRGWLDVSEISYIDLAKQMENIGVQTIVFTDISKDGTLAGPNIAQLELLQKSVSTRLIASGGIASIQDVKKLNDMNIYGVIIGKALYEKTIDLEEVLEVTKLC
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_SPIKU
Sequence: MSRSLKKGPFVDKYLQKKVEALNTANKKEVVKTWSRRSVIFPEFIGHTFAVHNGKEHIPVYVTEDMIGHKLGEFSPTRKFGGHGDDKKKKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: GNRHR_HORSE
Sequence: MANSASPEQNQNHCSASNSSIPLTQANLPTLTLSGKIRVTVTFFLFLLSTTFNASFLLKLHKWTQKKENGKKLSKMKVLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRPLAVKSNSKLGRSMIGLAWLLSSIFAGPQLYIFRMIHLADSSGQTEGFSQCVTHCSFPQWWHQAFYNFFTFSCLFIIPLLFMLICNAKIIFTLTRVLHQDPHKLQLNQSKNNIPRARLRTLKMTVAFATSFTVCWTPYYVLGIWYWFDPEMLNRVSDPVNHFFFLFALLNPCFDPLIYGYFSL
What is the function of this protein?
Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH).  This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).
What are the official names of this protein?
Gonadotropin-releasing hormone receptor, GnRH receptor, GnRH-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ASSY_CLOBA
Sequence: MNKLNKVILAYSGGLDTSIIIPWLKENYNCEVIAVCGNVGQKDELDGLEEKAIKTGASKLYMEDLTKEFVEDYIFPTIQAGAIYEGKYLLGTSFARPLIGKRLVEIAKVEGADAICHGCTGKGNDQVRFELAVKAFDPDMKIIAPWRIWDIKSREDEITYAEARNVPIKINHETNYSKDKNIWHLSHEGLDLEDPKNEPKYDEILELSNSLEKAPNEPTYITLTFEKGNAVALNGEKMDAVTLLDELNKIGGKNAIGITDMVENRLVGMKSRGVYETPGGTILYKAHKDLEELCLDKETSHYKEQISLKFADLVYNGLWFTPLREALSEFIKKTQETVTGEIKLKLYKGNIVNAGMTSPYSLYSEEYATFGEDAVYNQNDSAGFITLYGLPTVVKAKMYQSLKKEDK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_LACE2
Sequence: MVSKKSRTVVREQKHRRLRNRFSGTAERPRLAVFRSNNHMYAQIIDDTVGKTLVSASTLDKEVKAELEKTNNVEAAAAVGTVVAKRALEKGIKTVVYDRGGFIYAGKIKALAEAAREAGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: LFTR_CELJU
Sequence: MIPWLSPYSLEFPDVRLALDEPNGLLALGGDLSPERLVSAYQRGIFPWFNPGDPILWWSPHPRTVVFPHQHHVSRSLRKTLRKGIYRVTFDHCFAQVMRACAAPRAYANGTWISEQMISSYTRLHEQGYAHSVEVWQDENLVGGLYGLSLGKIFFGESMFSRADNASKTGFAYLVRQLQQWDFRLIDCQVASDHLFTLGAVEISRDEFQKMLVHFTEQPRDYPLHWHEIDPETRW
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27A_ENCCU
Sequence: MTDRVKKTRKLRGHVSHGYGRVGKHRKHSGGRGLAGGFSHMKTFFTRFHPDYHGKRGMRVYHRKENSDYARPISSARLWGMIPKEQRYDFLDNPEKVPVIDVREFGYHVVVGGKLSLERPIVVKARYFTPSAKEEITKVGGKWIITY
What are the official names of this protein?
60S ribosomal protein L27a.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: APAG_PSEE4
Sequence: MSDPRYQIDVSVVTRYLKDQSDPENDRFAFAYTITVQNNGTVKAKLMSRHWLITNGDGEVEEVRGAGVIGQQPLIEPGQSHTYSSGAVISTRVGTMQGSYQMFAEDGKRFDATIAPFRLAVPGALH
What are the official names of this protein?
Protein ApaG.
Protein: TRHBO_BACSU
Sequence: MGQSFNAPYEAIGEELLSQLVDTFYERVASHPLLKPIFPSDLTETARKQKQFLTQYLGGPPLYTEEHGHPMLRARHLPFPITNERADAWLSCMKDAMDHVGLEGEIREFLFGRLELTARHMVNQTEAEDRSS
What is the function of this protein?
Hemoglobin-like protein that exhibits a low peroxidase activity.  Its very high oxygen affinity may rule out the possibility that it is involved in oxygen transport.
What are the official names of this protein?
Group 2 truncated hemoglobin YjbI, Truncated Hb, trHbO, Hemoglobin-like protein YjbI, Truncated BHb.
What is the protein family that this protein belongs to?
Belongs to the truncated hemoglobin family. Group II subfamily.
Protein: QQT2_ARATH
Sequence: MDPMESSSEQDIVEESQKLVDSLDKLRVSAASSSSNFKKKPIIIIVVGMAGSGKTSFLHRLVCHTFDSKSHGYVVNLDPAVMSLPFGANIDIRDTVKYKEVMKQYNLGPNGGILTSLNLFATKFDEVVSVIEKRADQLDYVLVDTPGQIEIFTWSASGAIITEAFASTFPTVVTYVVDTPRSSSPITFMSNMLYACSILYKTRLPLVLAFNKTDVADHKFALEWMEDFEVFQAAIQSDNSYTATLANSLSLSLYEFYRNIRSVGVSAISGAGMDGFFKAIEASAEEYMETYKADLDMRKADKERLEEERKKHEMEKLRKDMESSQGGTVVLNTGLKDRDATEKMMLEEDDEDFQVEDEEDSDDAIDEDDEDDETKHYYL
What is the function of this protein?
Small GTPase that is essential for the correct formation of the tangential divisions in early embryos.  Associates with microtubule during mitosis and may function in the positioning of the division plane.  May participate in the patterning of the early embryo at the octant-dermatogen transition.
What are the official names of this protein?
GPN-loop GTPase QQT2, Protein QUATRE QUART 2.
What is the protein family that this protein belongs to?
Belongs to the GPN-loop GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, phragmoplast. Note=During interphase, mainly expressed in the cytoplasm and weakly in the nucleus. Associated with microtubules during cell division.
Protein: CWP06_TOBAC
Sequence: GEQPGDQARGARNPXGNN
What are the official names of this protein?
56 kDa cell wall protein.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: ZAT11_ARATH
Sequence: MKRERSDFEESLKNIDIAKCLMILAQTSMVKQIGLNQHTESHTSNQFECKTCNKRFSSFQALGGHRASHKKPKLTVEQKDVKHLSNDYKGNHFHKCSICSQSFGTGQALGGHMRRHRSSMTVEPSFISPMIPSMPVLKRCGSSKRILSLDLNLTPLENDLEYIFGKTFVPKIDMKFVL
What is the function of this protein?
Probable transcription factor that may be involved in stress responses.
What are the official names of this protein?
Zinc finger protein ZAT11.
What are the subcellular locations of this protein?
Nucleus.
Protein: ADH4_YEAS7
Sequence: MSSVTGFYIPPISFFGEGALEETADYIKNKDYKKALIVTDPGIAAIGLSGRVQKMLEERGLNVAIYDKTQPNPNIANVTAGLKVLKEQNSEIVVSIGGGSAHDNAKAIALLATNGGEIGDYEGVNQSKKAALPLFAINTTAGTASEMTRFTIISNEEKKIKMAIIDNNVTPAVAVNDPSTMFGLPPALTAATGLDALTHCIEAYVSTASNPITDACALKGIDLINESLVAAYKDGKDKKARTDMCYAEYLAGMAFNNASLGYVHALAHQLGGFYHLPHGVCNAVLLPHVQEANMQCPKAKKRLGEIALHFGASQEDPEETIKALHVLNRTMNIPRNLKELGVKTEDFEILAEHAMHDACHLTNPVQFTKEQVVAIIKKAYEY
What is the function of this protein?
Reduces acetaldehyde to ethanol during glucose fermentation.  Specific for ethanol.  Shows drastically reduced activity towards primary alcohols from 4 carbon atoms upward.  Isomers of aliphatic alcohol, as well as secondary alcohols and glycerol are not used at all (By similarity).
What are the official names of this protein?
Alcohol dehydrogenase 4, Alcohol dehydrogenase IV, ADHIV.
What is the protein family that this protein belongs to?
Belongs to the iron-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CATNT_HALH5
Sequence: MDDVIKKGLSIVSELRDHGFEAYIVGGAVRDYHIGRKPKDVDVVTSASPEEIRTLYPHAFQINRQFQTLTVHLQKVAIEVSTLRGGSIEDDLCSRDFTINAMALAMNGDIIDPTGGKTDLENGVIRSFHPEARFKEDPLRMLRAPRFASELGFTVAKGTAEAIKGSCSLLADVAVERVEKELTQLMIGTHRSSGWCLLHETGLYPFIPGVSLSKETVLRMKEISRSPGLLPADGFWAILYLLENCSMKLPLAKEKKKRIRTIVHYVGERQNHSWNETMLYQASLSVATVVEQIRALFGQASVHEEELRQLWSSLPIQTRTELAVTGRDVMAHFQKKGGPWLADTLADIEEAVLLKHIENEKKSIIQWLEERRVES
What is the function of this protein?
tRNA nucleotidyltransferase involved in the synthesis of the tRNA CCA terminus.  Adds the two cytidine residues to tRNA.
What are the official names of this protein?
CC-adding tRNA nucleotidyltransferase, C-adding TNT, CC-adding enzyme, NTSFI.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
Protein: Y148_MYCPN
Sequence: MERKVDHFQMTYQSFKDLSIKAKLSYTFNWFGDYSSGGFTAKKGDKHYFDLFLKIKPDPNKSFKAANFKTEEKNSTAIDGQETTRNLEWIEFGASISWSLKGKDDASEKSVKQFLDSYANNTSGYSSDINLFSYLEYLIR
What are the official names of this protein?
Uncharacterized protein MPN_148.
What is the protein family that this protein belongs to?
Belongs to the MG439/MG440 family.
Protein: NDHJ_SYNJA
Sequence: MTEDKAQQKPSSTAEPTEPLATLERGPVSQFLADNGFDHQYLGRDAAGVELLEVERDFLLPVCTALYAYGFNYLECQCGYDLGAGQPLVSLYHLIKLADGADRPQEVRVQVKLPRQDPRVPSVYWIWKSADWQERETYDMYGIIFEGHPNLKRILMPEDWIGWPLRKDYITPDFYELQDAY
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit J, NAD(P)H dehydrogenase subunit J, NADH-plastoquinone oxidoreductase subunit J, NDH-1 subunit J, NDH-J.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YMP9_CAEEL
Sequence: MFVLSIALLSCTTLCAATTEWWGDLRAHLNPARQAPFYDVTYDEKVNVCPQGLHADAIPEYVYFGTMLATMTVDEHDQCLQKCAEKPRCKAVNFFHPFAYQEKGFCELLTEGQLDNPSLMRPFRKATYYEKIRCRELDDVEDVEEAAPIGSEITEKLPEDMAREKKLDMSKLMKKLSAKVKEFNGGAGGFRAAR
What are the official names of this protein?
Uncharacterized protein B0361.9.
Protein: RS10_LEGPL
Sequence: MSSNQNIKIRLKSFDHRLIDLSTREIVDTAKRTGAQIRGPIPLPIRKEKFTVLTSPHVNKDARDQYELRTHKRLVVIVHPTEKTVDALMKLDLAAGVDVQISLDD
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: PSB_MYCTK
Sequence: MTWPLPDRLSINSLSGTPAVDLSSFTDFLRRQAPELLPASISGGAPLAGGDAQLPHGTTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAVELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAGRIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDDSATGGPDLVRGIFPTAVIIDADGAVDVPESRIAELARAIIESRSGADTFGSDGGEK
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta, 20S proteasome beta subunit, Proteasome core protein PrcB.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ETV2_HUMAN
Sequence: MDLWNWDEASPQEVPPGNKLAGLEGAKLGFCFPDLALQGDTPTATAETCWKGTSSSLASFPQLDWGSALLHPEVPWGAEPDSQALPWSGDWTDMACTAWDSWSGASQTLGPAPLGPGPIPAAGSEGAAGQNCVPVAGEATSWSRAQAAGSNTSWDCSVGPDGDTYWGSGLGGEPRTDCTISWGGPAGPDCTTSWNPGLHAGGTTSLKRYQSSALTVCSEPSPQSDRASLARCPKTNHRGPIQLWQFLLELLHDGARSSCIRWTGNSREFQLCDPKEVARLWGERKRKPGMNYEKLSRGLRYYYRRDIVRKSGGRKYTYRFGGRVPSLAYPDCAGGGRGAETQ
What is the function of this protein?
Binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3'.
What are the official names of this protein?
ETS translocation variant 2, Ets-related protein 71.
What is the protein family that this protein belongs to?
Belongs to the ETS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL3_DESPS
Sequence: MPKTMGILGKNIGMTRVYGEVGQAIPVTVVQAGPCKVLQVKTNATDGYNAVQVGFENKKSSRVNKAEAGHFAKSDSEGFYFVREFRVVDPATYNVGDMISVDALFKAGDIVDVQGTSKGRGFQGVIKRWGFKGGPGGHGSKHHRAPGSIGCSAYPGRVVKGKKMPGRMGNDTVLKKNVTVVDVRIDENVVLLKGPMPGAKNGLLKIYSK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: CDTS_MYCTU
Sequence: MSYVAAEPGVLISPTDDLQSPRSAPAAHDENADGITGGTRDDSAPNSRFQLGRRIPEATAQEGFLVRPFTQQCQIIHTEGDHAVIGVSPGNSYFSRQRLRDLGLWGLTNFDRVDFVYTDVHVAESYEALGDSAIEARRKAVKNIRGVRAKITTTVNELDPAGARLCVRPMSEFQSNEAYRELHADLLTRLKDDEDLRAVCQDLVRRFLSTKVGPRQGATATQEQVCMDYICAEAPLFLDTPAILGVPSSLNCYHQSLPLAEMLYARGSGLRASRNQGHAIVTPDGSPAE
What is the function of this protein?
Involved in the biosynthesis of mycocyclosin.  It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP-independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways.  Catalyzes the formation of cyclo(L-Tyr-L-Tyr) (cYY) from L-tyrosyl-tRNA(Tyr).  Can incorporate various nonpolar residues, such as L-phenylalanine, L-leucine, L-tyrosine and L-methionine, and to a much lesser extent L-alanine, into cyclodipeptides.  Cyclodipeptides synthesized by Rv2275 always contain L-tyrosine.
What are the official names of this protein?
Cyclo(L-tyrosyl-L-tyrosyl) synthase, Cyclodipeptide synthase, CDPS, Cyclodityrosine synthase.
What is the protein family that this protein belongs to?
Belongs to the CDPS family.
Protein: DNJC5_RAT
Sequence: MADQRQRSLSTSGESLYHVLGLDKNATSDDIKKSYRKLALKYHPDKNPDNPEAADKFKEINNAHAILTDATKRNIYDKYGSLGLYVAEQFGEENVNTYFVLSSWWAKALFVVCGLLTCCYCCCCLCCCFNCCCGKCKPKAPEGEETEFYVSPEDLEAQLQSDEREATDTPIVIQPASATETTQLTADSHPSYHTDGFN
What is the function of this protein?
Acts as a general chaperone in regulated exocytosis (By similarity).  Acts as a co-chaperone for the SNARE protein SNAP-25 (By similarity).  Involved in the calcium-mediated control of a late stage of exocytosis (By similarity).  May have an important role in presynaptic function.  May be involved in calcium-dependent neurotransmitter release at nerve endings (By similarity).
What are the official names of this protein?
DnaJ homolog subfamily C member 5, Cysteine string protein, CSP.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Membrane; Lipid-anchor. Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane. Melanosome. Cell membrane. Note=The association with membranes is regulated by palmitoylation.
Protein: RS6_NITHX
Sequence: MPLYEHVFLARQDASSQQVEELTNQITGVITGLGGKVTKTENWGVRSLTYRMKKNRKAHFVLLNIDGPAAVVSEIERQERIHEDVIRYLSIRVEEHEEGPSAMMRKADRDRERDDRGGGFRGDREGGFRGDRGPRRPREEAPAVVEE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: UNG_HELPJ
Sequence: MKLFDYAPLSLAWREFLQSEFKKPYFLEIEKRYLEALKSPKTIFPKSSNLFCAFNLTPPYAVKIILLGQDPYHSTYLENEQELPVAMGLSFSVEKNAPIPPSLKNIFKELHANLGVPVPCCGDLSAWAKRGMLLLNAILSVEKNQAASHKYIGWEAFSDQILIRLFETTTPLIVVLLGKVAQKKIALIPKNKHIIITAPHPSPLSRGFLGSGVFTSVQKAYREVYRKDFDFSL
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIM13_CRYNB
Sequence: MSSFFGSGAGSPSNDMTARKEQMKQSIQQELAIANAQQLINKINENCFAKCVTKPSTSLSSSQESCLSQCMTLYMAAFDQVSRSYVARISKERGVAPGL
What is the function of this protein?
Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane.  Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane.  Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.  The TIM8-TIM13 complex is non essential and only mediates the import of few proteins, while the predominant TIM9-TIM10 70 kDa complex is crucial and mediates the import of much more proteins (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit TIM13.
What is the protein family that this protein belongs to?
Belongs to the small Tim family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: RL21_NITMU
Sequence: MYAVIKTGGKQYRVENGLKLKIEQVPVEIGSELLIDQVLMVADGDNISLGKPLVSGASVKATVLEQGRHDKVRIFKMRRRKHYRKQQGHRQNYTEIQITGISV
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: PB1F2_I02A6
Sequence: MEQGQDTPWTQSTEHTNIQKRGSGQQTQRLEHPNSTRLMDHYLRIMSPVGMHKQIVYWKQWLSLKNPTQGSLKTRVLKRWKLFNKQEWIN
What is the function of this protein?
Plays an important role in promoting lung pathology in both primary viral infection and secondary bacterial infection.  Promotes alteration of mitochondrial morphology, dissipation of mitochondrial membrane potential, and cell death.  Alternatively, inhibits the production of interferon in the infected cell at the level of host mitochondrial antiviral signaling MAVS.  Its level of expression differs greatly depending on which cell type is infected, in a manner that is independent of the levels of expression of other viral proteins.  Monocytic cells are more affected than epithelial cells.  Seems to disable virus-infected monocytes or other host innate immune cells.  During early stage of infection, predisposes the mitochondria to permeability transition through interaction with host SLC25A6/ANT3 and VDAC1.  These proteins participate in the formation of the permeability transition pore complex (PTPC) responsible of the release of mitochondrial products that triggers apoptosis.
What are the official names of this protein?
Protein PB1-F2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB1-F2 family.
What are the subcellular locations of this protein?
Host mitochondrion inner membrane. Host nucleus. Host cytoplasm, host cytosol. Note=Inner mitochondrial membrane in most cells types. Otherwise is detected in the nucleus and cytosol.
Protein: RL1_LAWIP
Sequence: MPKLGKKYRNAVKGVDLSLHLSFEDAVTQSIQTSFANFDETVDIAIGLGVDPKYSDQMVRGAVTLPYGLGKTVRVAVFCKGEKEAEAKEAGADYAGAEELVAKIKDGWLDFDAAVATPDVMALVGQVGRQLGPRGLMPNAKTGTVTFNVTNAIKELKAGRIDFKVDKAGVLHAPLGKVSFGSEKILGNLKSLVETVNRLKPSSAKGTYIKSMAISTTMGPGFKIDTNLVKKFLES
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: PLXD1_MOUSE
Sequence: MARRAAGGAPPSARAAAAVPLRPRPHSRGPGLLPLPLLLLLGAARAGALEIQRRFPSPTPTNNFALDGTAGTVYLAAVNRLYQLSSANLSLEAEATVGPVPDSPLCHAPQLPQASCEHPRRLTDNYNKILQLDPGQGLVVACGSIYQGLCQLRRRGNISALAVSFPPAAPTAEPVTVFPSMLNVAANHPNASTVGLVLPPTSGTGGSRLLVGATYTGFGSAFFPRNRSLEDHRFENTPEIAIRSLDARGDLAKLFTFDLNPSDDNILKIKQGAKEQHKLGFVRAFLHPAVPPHSAQPYAYLALNSEARAGDKDSQARSLLARICLPRGAGGDAKKLTESYIQLGLQCAGGAGRGDLYSRLVSVFPAREQFFAVFERPQGAPGARNAPAALCAFRFDDVQAAIRAARTACFVEPAPDVVAVLDSVVQGTGPACESKRNIQLQPEQLDCGAAHLQHPLTILQPLRASPVFRAPGLTAVAVASANNYTAVFLGTATGRLLKISLNESMQVVSRRVLTVAYGEPVHHVMQFDPMDPGYLYLMTSHQMARVKVAACEVHSTCGDCVGAADAYCGWCTLETRCTLQQDCTNSSQPHFWTSASEGPSRCPAMTVLPSEIDVHRDYTGMILQISGSLPSLSGMEMACDYGNGVRTVARVPGPAYDHQIAYCNLLPRAQFPSFPAGQDHVTVEMSVRVKGHNIVSANFTIYDCSRIGQVYPHTACTSCLSTQWPCSWCIQLHSCVSNQSQCQDSPNPTSPQDCPQILPSPLAPVPTGGSQDILVPLTKATFFHGSSLECSFGLEESFEAVWANNSLVRCNQVVLHTTQKSQVFPLSLKLKGPPDRFLDSPNPMTVVVYNCAMGSPDCSQCLGREDLGHLCVWNDGCRLRGPLQPLPGTCPAPEIRAIEPLSGPLDGGTLLTIRGRNLGRRLSDVAHGVWIGSVACEPLADRYTVSEEIVCATGPAAGAFSDVVTVNVSKEGRSREQFSYVLPTVHSLEPSMGPKAGGTRITIHGSDLNVGSMLQVLVNDTDPCTDLTRTATSITCTVPGGTLPSPVPVCVRFESRGCVHGNLTFWYMQNPVITAISPGRSPVSGGRTITVAGERFHMVQNVSMAVHHIGREPTFCKVLNSTLITCPSPGALSNASAPVDFFINGRAYADEAAEELLDPAEAQRGSRFRLDYLPNPQFSTAKREKWIKHHPGEPLTLVIHKEQDSLGLESHEYHIKIGQVSCDIQIISDRVIHCSVNESLGTAEGQLPITIQVGNFNQTIATLQLGGSETAIVVSIVICSVLLLLSVVALFVFCTKSRRAERYWQKTLLQMEEMESQIREEIRKGFAELQTDMTDLTKELNRSQGIPFLEYKHFVTRTFFPKCSSLYEERYVLPSKTLNSQGGSPPQETHPLLGEWNIPEHCRPSMEEGISLFSSLLNNKHFLIVFVHALEQQKDFAVRDRCSLASLLTIALHGKLEYYTSIMKELLVDLIDASAAKNPKLMLRRTESVVEKMLTNWMSICMYGCLRETVGEPFFLLLCAIKQQINKGSIDAITGKARYTLNEEWLLRENIEAKPRNLNVSFQGCGMDSLSVRAMDTDTLTQVKEKILEAFCKNVPYSQWPRAEDVDLEWFASSTQSYVLRDLDDTSVVEDGRKKLNTLAHYKIPEGASLAMSLTDKKDSTLGRVKDLDTEKYFHLVLPTDELVEPKKSHRQSHRKKVLPEIYLTRLLSTKGTLQKFLDDLFKAILSIREDKPPLAVKYFFDFLEEQAEKRGISDPDTLHIWKTNSLPLRFWVNILKNPQFVFDIEKTDHIDACLSVIAQAFIDACSISDLQLGKDSPTNKLLYAKEIPEYRKTVQRYYKQIQDMTPLSEQEMNAHLAEESRKYQNEFNTNVAMAEIYKYAKRYRPQIMAALEANPTARRTQLQHKFEQVVALMENNIYECYSEA
What is the function of this protein?
Cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E.  Plays an important role in cell-cell signaling, and in regulating the migration of a wide spectrum of cell types.  Regulates the migration of thymocytes in the medulla.  Regulates endothelial cell migration.  Plays an important role in ensuring the specificity of synapse formation.  Mediates anti-angiogenic signaling in response to SEMA3E.  Required for normal development of the heart and vasculature.
What are the official names of this protein?
Plexin-D1.
What is the protein family that this protein belongs to?
Belongs to the plexin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Cell projection, lamellipodium membrane.
Protein: PDXT_BACC3
Sequence: MVKIGVLGLQGAVREHVKSVEASGAEAVVVKRIEQLEEIDGLILPGGESTTMRRLIDKYDFMEPLRTFAKSGKPMFGTCAGMILLAKTLIGYDEAHIGAMDITVERNAFGRQKDSFEAALSIKGVGEDFVGVFIRAPYVVDVADDVEVLSTHGDRMVAVRQGPFLAASFHPELTDDHRVTAYFVEMVKEAKMKKVV
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.