PharMolix/UniProtQA huggingface dataset:
Protein: MDH_CERS1
Sequence: MARPKIALIGAGQIGGTLAHLAAIKELGDVVLFDIAEGTPQGKALDIAQSGPSEGFDAVMKGANSYEEIAGADVCIVTAGVPRKPGMSRDDLIGINLKVMKSVGEGIKAHAPNAFVICITNPLDAMVWALQQFSGLPAEKVVGMAGVLDSARFRHFLSVEFNVSMRDVTAFVLGGHGDTMVPLVRYSTVAGIPLPDLVQMGWTTQEKLDQIVQRTRDGGAEIVGLLKTGSAFYAPATSAIEMAEAYLKDQKRLLPCAAYVDGAFGLNGMYVGVPTIIGAGGIEKIVDIKLNDDEQAMFDKSVNAVKGLVEACKGIDSSLA
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: SFSA_MARN8
Sequence: MKFSEPLVEGRLIRRYKRFLADVQLPDGTEVTAHCPNTGSMLGCQPENARVWLSRSDNPKRKLQYTWELVETEPGVLACVNTVRPNAQARAAIEAGVVQSLAGYAQCRAEVRYGSEKSRIDLLLSGHDHDPDAWVEVKNVTLAEGGEGYFPDAVTERGQKHLRELMAQVQNGDRAVLFFVVNHTGIEQVRPADHIDARYGQLLREACEAGVEVIAYRAALAGEDGDPSGRLELVEEVPVSLEP
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: DDL_CORU7
Sequence: MTAAEKLTVAVVYGGQSTEHSVSCISAGAIIDNLDPERFTVVPVGITNGGAWVPGATDTAQLRASGRELPTVADHGEHIQPMLGAAGEATEFRFVTGDRAGDVFATADVIFPVLHGANGEDGTIQGLFDLLGARYVGNGVLASAAGMDKEFTKKIAREAGIPTGPEVVLHGRTELTDHERELLGLPVFVKPARGGSSIGISKVDSWRDLPAAIEEAASHDPKVIIEAMITGPEVECGVLEREDGTLVASSPAMLEGTDAGEEGFYGFDAKYLDDTVSATIPAPLDEETTRRVQQLAIETYRALGCTGLARVDFFVTDAGPVLNEINTMPGFTPISMYPQMFLADGVSYADLLTTLVSGARRH
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH10_BOVIN
Sequence: MAGQAFRKFLPLFDRVLVERSAAETVTKGGIMLPEKSQGKVLQATVVAVGSGSKGKGGEIQPVSVKVGDKVLLPEYGGTKVVLDDKDYFLFRDGDILGKYVD
What is the function of this protein?
Co-chaperonin implicated in mitochondrial protein import and macromolecular assembly.  Together with Hsp60, facilitates the correct folding of imported proteins.  May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.  The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back-to-back double ring.  In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per ring, followed by the binding of ATP and association with 2 heptameric rings of the co-chaperonin Hsp10.  This leads to sequestration of the substrate protein in the inner cavity of Hsp60 where, for a certain period of time, it can fold undisturbed by other cell components.  Synchronous hydrolysis of ATP in all Hsp60 subunits results in the dissociation of the chaperonin rings and the release of ADP and the folded substrate protein.
What are the official names of this protein?
10 kDa heat shock protein, mitochondrial, Hsp10, 10 kDa chaperonin, Chaperonin 10, CPN10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
Protein: PROB_BURCH
Sequence: MRSIIADSKRLVVKVGSSLVTNDGKGLDHAAIGRWAAQIAALRAQGKEVVLVSSGAIAEGMQRLGWSKRPREIDELQAAAAVGQMGLAQVYESRFTEHGIRTAQILLTHADLADRERYLNARSTLLTLLRLGVVPIINENDTVVTDEIKFGDNDTLGALVANLIEGDALIILTDQSGLFTADPRKDPNATLVGEANAGAPELEAMAGGAGSSLGRGGMLTKILAAKRAAHSGANTVIASGREADVLVRLAAGEAIGTQLIARTARMAARKQWMADHLQVRGHVVIDAGAVEKLTAGGKSLLPIGVIDVQGAFARGEVIACVGPDGREVARGLTNYSSAETKLIHRKPSGEIETVLGYMLEPELIHRDNLVLV
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU214_CAEEL
Sequence: MSNEDVAEDVSQVTDFHFHTCRKFRLFSSKSDGYSQNEINIRNRVATSSQLGVTFVTVNSNQLSCFHTKSLLGYKITRENMNVEVTDLPIKTIRLHGVVLINDMGVNSDGTVLGVLHTKNNDVSVDVFDIKKICTSSSIEPFKPLCTTRVGTEQINQGSCLEWNPAFPDTFAASSTDRSILVAKINVQSPANQKLVGIGKFGAVTTAISWSPKGKQLTIGDSLGKIVQLKPELEVVRSQHGPENKPNYGRITGLCWLATTEWLVSLENGTDQDAYLMRCKKDKPTEWIQFHELSYSSSKWPLPPQLFPATQLLVDWNVVIVGNSKTSEISTVGKRDDWQTWVPVEGESIYLPTTSSGKDTVPIGVAVDRSMTDEVLLNPDGSQRHRPSPLVLCLTNDGILTAHHIISTFAAHIPCQMSSQNLAINDLKKLQFDSQKPISAPPSDQTPVTKPSTVFGQKPEAETLKSSLVGSPSSVQTPKPSSSLFNPKSIASNIETSQLTESKPSTPAAPSSQPKIASTPKSEAIPKISDKTLEHKKAELIATKKQVLIERMDKINDSMAGAKDATMKLSFAVGKVKTTIMECADVVRASLGDSKEVMDELKNLILSIERMSDRTQHTVKEMDFEIDEKMELVAGVEDGNQVLEKLRNMSETEKLMRFNKLETAADLLNGKYEECSDLIKKLRMSLSEKESLRKQAILSPLRLSSNLNQLRSGSETELALKVMRNVSKIIMDTREQIQRTELEFVRFQRDVKFQNFKKGKENLNFTQPLEMSSLDGDAPQGKSLTDAESIKVRQALVNQIQKRGIVKTRNVIVESYKKSENSAAMKNDLLDTSNLSNAILKLSMTPRRVMPSSSLFSASPSTPSTKSDAATQADEPPIVKTVVVTVESPAKPIASAPAVSSPLIKLNTTTATTTMTTPKVTVPKEEANKTQDQKPIISTPASSSIFSSGSLFGTKTQTPLVSKEESTLTTGVPSLINSSLSISPQEIEKASSKVETLNKTEEVKDEKSENEVTPDLKSEEPKSLETKVKEEPKPAVQTPVKEEETGSNIQKTPSFSFNSTTTPKSTSSTSSIFGGGLKTQTPSSSNSTNIFGARTTTTATPTPASNTSSIFGGGSKAASSPFGSFGQAGCQPAKTSNPATSTASVTFSFNTGATSASAKPAGFGSFGAGASAKPSSVFGGSVTAPTVPNVDDGMEDDSMANGGGSGGFMSGLGNARTSNTSGGNNPFAPKTSTGTSASSSSWLFGGGGNQQQQQQQKPSFSFNTAGSSAQQASAPATGTSSVFGGAPKFGSQPAFGAKPFGGGANAGLSKNASIFGGATSSTTNNPATGGFAQFASGQKTSSLFGGGATPQTNTSIFGGGANTTPAPTSSVFGGGASANANKPTSFTSWR
What is the function of this protein?
May serve as a docking site in the receptor-mediated import of substrates across the nuclear pore complex (By similarity).  Plays a role in apoptosis by tethering caspase ced-3 to the nuclear membrane preventing its autoprocessing in absence of ced-4.
What are the official names of this protein?
Nuclear pore complex protein 14, Nuclear pore complex protein Nup214, Nucleoporin npp-14.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein. Note=Cytoplasmic side of the nuclear pore complex (By similarity). Co-localizes with caspase ced-3 to the perinuclear region in germ cells.
Protein: HEM0_CERS4
Sequence: MEFSQHFQKLIDDMRLDGRYRTFAELERIAGEFPTALWHGPDGQARRVTVWCSNDYLGMGQNAEVLAAMHRSIDLSGAGTGGTRNISGTNRQHVALEAELADLHGKESALIFTSGWISNLAALGTLGKILPECAIFSDALNHNSMIEGIRRSGAERFIFHHNDPVHLDRLLSSVDPARPKIVAFESVYSMDGDIAPIAEICDVAERHGALTYLDEVHAVGLYGPRGGGISDRDGLADRVTIIEGTLAKAFGVMGGYVSGPSLLMDVIRSMSDSFIFTTSICPHLAAGALAAVRHVKAHPDERRRQAENAVRLKVLLQKAGLPVLDTPSHILPVMVGEAHLCRSISEALLARHAIYVQPINYPTVARGQERFRLTPTPFHTTSHMEALVEALLAVGRDLGWAMSRRAA
What are the official names of this protein?
5-aminolevulinate synthase 2, 5-aminolevulinic acid synthase, Delta-ALA synthase, Delta-aminolevulinate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
Protein: TAL_BORA1
Sequence: MPSQLEALRRHTTVVADTGDFETMRALRPTDATTNPSLILKAVQQAAYRPLLDQVARDHRGAPLAEITDRLLVAFGRQILDIVPGRVSTEVDARLSFDTRATIERARSLIALYEAAGVARERVLIKIASTWEGIQAARLLQQEGIRCNLTLLFSLVQAAACAEAGVQLISPFVGRIYDWHKKAAGAQWNEAQQSGVNDPGVQSVARIFAYYKAYGVATEVMGASFRNTGQILALAGCDLLTISPELLARLDATEGEVPLSLSEPLPGAALPKALPSGEIAFRSLLNEDAMASEKLAEGIRLFVGDAQRLDDLLRAAGAY
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_DESVM
Sequence: MEYTVEDLSPVKKKVNISVPVEEVEAALSAAIAMYRTNMSLDGFRKGKVPSNLVESRFRKEIYGEATQDLVNVHINEVMTALDANPISRIDFDGGQLERGTPFEYSISFEVLPEFDLPDYDGFAVEQEKAVVDMKEVDEVITRIRTNMAELVPVAEARPGKDGDVVVLDFAAFENGEPVEGISAENFQMNLGDRQALEDFENLVKTLAPGQEGEGPLNFPADFINPDFAGKSLTVKVKVHAVKERRLPEANDELAQKAGGFESMDKMREAVTSSYMQSRTQLVKATAQKTMLDKLLKMVDFPLPESMVDMYVGHLLDDMRSKLERQGKSMESLGKKPEELRAEVRPEAEQVTRTQIFLLRAARKEGVEVNEQEIDGQIQQIAMRSGQDYNALKDYYIKNNLIFSLRDRMLADKAMDAIYEKAAVTEVEPAAK
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: RS3_ACISJ
Sequence: MGQKIHPTGFRLSVSRNWASRWYASNRDFAGMLAEDIKVREYLKAKLKNAAVSRILIERPAKNARITIFSARPGVVIGKKGEDIENLKKELATRLGVPVAVNIEEVRKPEIDAKLIADSITQQLEKRIMFRRAMKRAMQNAMRLGAQGIKIMSSGRLNGIEIARTEWYREGRVPLHTLRADIDYGTSEAKTTYGVIGVKVWVYKGDTLGRNDLPAAETPRPEEERRPRGPRRDGRPGDRAGAGRGGRRPMGTNAAPADGSDKPAGAGGDSVKRVKSAPAAAAADGKGE
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: PSBZ_HELAN
Sequence: MTLAFQLAVFALIATSSILLIGVPVVFASPDGWSSNKNVVFSGTSLWIGLVFLVGILNSLIS
What is the function of this protein?
Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna.
What are the official names of this protein?
Photosystem II reaction center protein Z, PSII-Z.
What is the protein family that this protein belongs to?
Belongs to the PsbZ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein. Note=Associated with the photosystem II complex.
Protein: MALQ_MYCTO
Sequence: MTELAPSLVELARRFGIATEYTDWTGRQVLVSEATLVAALAALGVPAQTEQQRNDALAAQLRSYWARPLPATIVMRAGEQTQFRVHVTDGAPADVWLQLEDGTTRAEVVQVDNFTPPFDLDGRWIGEASFVLPADLPLGYHRVNLRSGDSQASAAVVVTPDWLGLPDKLAGRRAWGLAVQLYSVRSRQSWGIGDLTDLANLALWSASAHGAGYVLVNPLHAATLPGPAGRSKPIEPSPYLPTSRRFVNPLYLRVEAIPELVDLPKRGRVQRLRTNVQQHADQLDTIDRDSAWAAKRAALKLVHRVPRSAGRELAYAAFRTREGRALDDFATWCALAETYGDDWHRWPKSLRHPDASGVADFVDKHADAVDFHRWLQWQLDEQLASAQSQALRAGMSLGIMADLAVGVHPNGADAWALQDVLAQGVTAGAPPDEFNQLGQDWSQPPWRPDRLAEQEYRPFRALIQAALRHAGAVRIDHIIGLFRLWWIPDGAPPTQGTYVRYDHDAMIGIVALEAHRAGAVVVGEDLGTVEPWVRDYLLLRGLLGTSILWFEQDRDCGPAGTPLPAERWREYCLSSVTTHDLPPTAGYLAGDQVRLRESLGLLTNPVEAELESARADRAAWMAELRRVGLLADGAEPDSEEAVLALYRYLGRTPSRLLAVALTDAVGDRRTQNQPGTTDEYPNWRVPLTGPDGQPMLLEDIFTDRRAATLAEAVRAATTSPMSCW
What are the official names of this protein?
4-alpha-glucanotransferase, Amylomaltase, Disproportionating enzyme, D-enzyme.
What is the protein family that this protein belongs to?
Belongs to the disproportionating enzyme family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BRL3_ORYSJ
Sequence: MAAVRVVAPAPSVLLLVAAAVVLLHLARAIAGAADEAAALLAFKDASVAADPGGALAGWANSTTPGSPCAWAGVSCAAGRVRALDLSGMSLSGRLRLDALLALSALRRLDLRGNAFHGDLSRHGSPRRAAPCALVEVDISSNTFNGTLPRAFLASCGGLQTLNLSRNSLTGGGYPFPPSLRRLDMSRNQLSDAGLLNYSLTGCHGIQYLNLSANQFTGSLPGLAPCTEVSVLDLSWNLMSGVLPPRFVAMAPANLTYLSIAGNNFSMDISDYEFGGCANLTLLDWSYNRLRSTGLPRSLVDCRRLEALDMSGNKLLSGPIPTFLVELQALRRLSLAGNRFTGEISDKLSILCKTLVELDLSSNQLIGSLPASFGQCRFLQVLDLGNNQLSGDFVETVITNISSLRVLRLPFNNITGANPLPALASRCPLLEVIDLGSNEFDGEIMPDLCSSLPSLRKLLLPNNYINGTVPSSLSNCVNLESIDLSFNLLVGQIPPEILFLLKLVDLVLWANNLSGEIPDKFCFNSTALETLVISYNSFTGNIPESITRCVNLIWLSLAGNNLTGSIPSGFGNLQNLAILQLNKNSLSGKVPAELGSCSNLIWLDLNSNELTGTIPPQLAAQAGLITGAIVSGKQFAFLRNEAGNICPGAGVLFEFLDIRPDRLANFPAVHLCSSTRIYTGTTVYTFRNNGSMIFLDLSYNSLTGTIPASFGNMTYLEVLNLGHNELTGAIPDAFTGLKGIGALDLSHNHLTGVIPPGFGCLHFLADFDVSNNNLTGEIPTSGQLITFPASRYENNSGLCGIPLNPCVHNSGAGGLPQTSYGHRNFARQSVFLAVTLSVLILFSLLIIHYKLWKFHKNKTKEIQAGCSESLPGSSKSSWKLSGIGEPLSINMAIFENPLRKLTFSDLHQATNGFCAETLIGSGGFGEVYKAKLKDGNIVAVKKLMHFTGQGDREFTAEMETIGKIKHRNLVPLLGYCKIGDERLLVYEYMKNGSLDFVLHDKGEANMDLNWATRKKIAIGSARGLAFLHHSCVPHIIHRDMKSSNVLLDGNFDAYVSDFGMARLMNALDSHLTVSMLSGTPGYVPPEYCQDFRCTTKGDVYSYGVVLLELLTGKKPIDPTEFGDSNLVGWVKQMVEDRCSEIYDPTLMATTSSELELYQYLKIACRCLDDQPNRRPTMIQVMTMFKEFQVDSGSNFLDDFSLNSTNMEESSEKSV
What is the function of this protein?
May be involved in brassenosteroid (BR) perception in roots.
What are the official names of this protein?
Brassinosteroid LRR receptor kinase BRL3, BRI1-like receptor kinase 3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: TRPF_STAAB
Sequence: MKLKFCGFTSIEDVTAASQLPIDAIGFIHYEKSKSHQTITQIKKLASAVPEHIDKVCVVVNPDLTTIEHVLSNTPINTIQLHGTESIDFIQEIKKKYSSIKITKALAADENIIQNINKYKGFVDLFIIDTPSVSYGGTGQTYDWTILKHIKDIPYLIAGGINSENIQTVNQLKLSHQGFDLASGIEVNGRKDIEKMTAIVNIVKGDRENE
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: NBL1_RAT
Sequence: MLWVLVGTVLPVMLLAAPPPINKLALFPDKSAWCEAKNITQIVGHSGCEAKSIQNRACLGQCFSYSVPNTFPQSTESLVHCDSCMPAQSMWEIVTLECPGHEEVPRVDKLVEKIVHCSCQACGKEPSHEGLNVYMQGEDGPGSQPGSHSHSHPHPGCQTPEPEEPPGAPQVEEEGAED
What is the function of this protein?
Possible candidate as a tumor suppressor gene of neuroblastoma.  May play an important role in preventing cells from entering the final stage (G1/S) of the transformation process.
What are the official names of this protein?
Neuroblastoma suppressor of tumorigenicity 1, N03, Zinc finger protein DAN.
What is the protein family that this protein belongs to?
Belongs to the DAN family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL6_STRP4
Sequence: MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIRVEGTEITXHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSKLVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGKGIRYVGEFVRRKEGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RL23_NOCFA
Sequence: MTTIADPRDILLAPVISEKSYGLIEEGTYTFLVHPDSNKTQIKIAVEKVFGVKVTSVNTANRQGKRKRTRFGYGKRKNTKRALVTISADSKPIEIFGGPVA
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: PGCB_FELCA
Sequence: MAPLFLPLLIALALAPGPTASADVLEGDSSEDRAFRVRISGNAPLQGVLGGALTISCHVHYLRPPPGRRAVLGSPRVKWTFLSGGREAEVLVARGLRVKVSEAYRFRVALPAYPASLTDVSLALSELRPNDSGIYRCEVQHGIDDSSDAVEVKVKGVVFLYREGSARYAFSFARAQEACARIGARIATPEQLYAAYLGGYEQCDAGWLSDQTVRYPIQTPREACYGDMDGFPGVRNYGLVDPDDLYDIYCYAEDLNGELFLGAPPDNVTLEEATAYCRERGAEIATTGQLYAAWDGGLDRCSPGWLADGSVRYPIVTPSQRCGGGLPGVKTLFLFPNQTGFPNKYSRFNVYCFRDSGQPSTTPEASXPASDGLEAIVTVTETLEELHVPREAVESESRGAIYSVPIVEDGGGARSPP
What is the function of this protein?
May play a role in the terminally differentiating and the adult nervous system during postnatal development.  Could stabilize interactions between hyaluronan (HA) and brain proteoglycans.
What are the official names of this protein?
Brevican core protein, Brain-enriched hyaluronan-binding protein, BEHAB.
What is the protein family that this protein belongs to?
Belongs to the aggrecan/versican proteoglycan family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: PACA_BOVIN
Sequence: MTMCSGARLALLVYGILMHSSVYGSPAASGLRFPGIRPENEVYDEDGNPQQDFYDSESLGVGSPASALRDAYALYYPAEERDVAHGILNKAYRKVLDQPSARRSPADAHGQGLGWDPGGSADDDSEPLSKRHSDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNKGRRIPYL
What is the function of this protein?
Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells (By similarity).  Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway (By similarity).  In chromaffin cells, induces long-lasting increase of intracellular calcium concentrations and neuroendocrine secretion (By similarity).  Involved in the control of glucose homeostasis, induces insulin secretion by pancreatic beta cells (By similarity).
What are the official names of this protein?
Pituitary adenylate cyclase-activating polypeptide, PACAP.
What is the protein family that this protein belongs to?
Belongs to the glucagon family.
What are the subcellular locations of this protein?
Secreted.
Protein: HME2B_XENLA
Sequence: MEENEQNNREVEPQQESGEESNRGILHQAPPGNHQPHHRITNFFIDNILRPEFGRRKERINHQDELFTGRDTGALSGAESGHHRVNVPEGAGGSSKVITVTGEKKSDLAMEETLKSRGLNGDHSLSSDSDSSQASSKATQKPILWPAWVYCTRYSDRPSSGPRSRKPKKKSVSKEDKRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELGLNESQIKIWFQNKRAKIKKSTGNKNSLALHLMAQGLYNHATTSKDGKSDSE
What are the official names of this protein?
Homeobox protein engrailed-2-B, En-2B, Homeobox protein en-2-B, En2 MABEN.
What is the protein family that this protein belongs to?
Belongs to the engrailed homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NSS_BUNL7
Sequence: MMSHQQVQINLILMQGIWTSVLKMQNHSTLLQLGSSSTMPQRPRLLS
What is the function of this protein?
Inhibits host transcriptional machinery, by producing modifications to the phosphorylation state of the C-terminal domain (CTD) of RNA polymerase II.  Inhibits phosphorylation at serine 2 in the heptapeptide repeat (YSPTSPS) of the CTD of RNA polymerase II, suggesting that the elongation step of transcription and/or 3'-end processing is prevented.  Inhibition of host transcription machinery leads to shut off of host cell protein synthesis and inhibition of the host innate immune response.  NSs also seems to be involved in the nuclear relocalization of host PABP1 (By similarity).
What are the official names of this protein?
Non-structural protein NS-S.
What is the protein family that this protein belongs to?
Belongs to the orthobunyavirus NS-S protein family.
Protein: ATPE_THAPS
Sequence: MVMDIRVLTPDRVICSTTADEVILPGLTGQVGVLDGHATLITALDTGLLRIKLADKWTPIILCGGLAEIDRNRVTVLVNDVEELVAVELSEATKELEKATSAIENAETSKARLDASVELKKATARLEGINYLS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, chloroplastic, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: ATPG_LACP7
Sequence: MASMRDIKRRKESIQSTGQITKAMKLVSTVKLQKAKSKAENAKPYFDHMYDTVLNMLRKSGNISHPYLSAGKSNKKAIIVITSNRGLAGGYNSNILKLVMSSDINKEDAVVYAVGRKGKEALARRGYHIAKDYSEVMNAPIYKDAIEIGKAVLDAFVADEVGEIYLAYTSFKNTVSHEPTLIKLLPVDMEAALQEGEKSEDLNERLTLMNYEPAAEEALNLIIPKYINSLIYGALVQALASENGARMQAMDSATNNAEDMISDLSLKYNRARQSSITQELTEIIAGANAIN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: IL24_RAT
Sequence: MQTSLRQQILPGLSLILLVLNQVPELQGQEFRFGPCQVTGVVLPELWEAFWTVKNTVKTQDELTSVRLLKPQVLQNVSDAESCYLAHSLLKFYLNTVFKNYHSKIVKFKVLKSFSTLANNFLVIMSKLQPSKDNAMLPISDSARRRFLLYHRTFKQLDIEVALAKAFGEVDILLAWMQNFYQL
What is the function of this protein?
Multifunctional cytokine mainly produced by T-cells that plays a regulatory role in immune response, tissue homeostasis, host defense, and oncogenesis.  Possesses antiviral functions and induces the type I intereferon response during influenza infection.  Signals through two receptor complexes IL20RA/IL20RB or IL20RB/IL22RA1.  In turn, stimulates the JAK1-STAT3 and MAPK pathways and promotes the secretion of pro-inflammatory mediators including IL8 and MMP1 (By similarity).  Intracellularly, maintains endoplasmic reticulum homeostasis by restricting the eIF2alpha-CHOP pathway-mediated stress signal (By similarity).  In addition, acts as a quality control mechanism for the ubiquitin proteasome system by alerting the cell to proteasome dysfunction through activation of PKR/EIF2AK2 (By similarity).
What are the official names of this protein?
Interleukin-24, IL-24, Cytokine-like protein Mob-5.
What is the protein family that this protein belongs to?
Belongs to the IL-10 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SNAT_PANTR
Sequence: MSMQSTHPPKPEAPRLPPGIPESPSCQRRHTLPASEFRCLTPEDAVSAFEIEREAFISVLGVCPLDLDEIRHFLTLCPELSLGWFEEGCLVAFIIGSLWDKERLMQESLTLHRSGGHIAHLHVLAVHRAFRQQGRGPILLWRYLHHLGSQPAVRRAALMCEDALVPFYERFSFHAVGPCAITVGSLTFTELHCSLRDHPFLRRNSGC
What is the function of this protein?
Controls the night/day rhythm of melatonin production in the pineal gland.  Catalyzes the N-acetylation of serotonin into N-acetylserotonin, the penultimate step in the synthesis of melatonin (By similarity).
What are the official names of this protein?
Serotonin N-acetyltransferase, Serotonin acetylase, Aralkylamine N-acetyltransferase, AA-NAT.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. AANAT subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_BUCA5
Sequence: MPVIRFYDGSQQVYEHSVSLIEIIKNKKPSIMKSLIAISVNNHFSNLNTFIREDAFIEFVDQKNYKALNIIRYSCAQLLSYAIKNIWPLAQIATSNIIEDGFYCDIDFKRSISEKDLILLENQMKTLVKREYNILNKLISYSEAREIFQKCFEKYKVSLIDENINCNSKVSLYYHENYADIDIGLQVFNIKFCKYFKLQKIGGVYWKKNKNNKMLQRIYGTAWTNKQELDKHLDYLNELEKRDHRKIGKFLQLYHMQEESPGMIFWHNKGWIIFNELQNFVRVKLKEYKYEEVKTPLLIDKLIWKQSGHWDNYKNAIFTTLSEHREYCIKPMNCPGHVQIFNSRLKSYRDLPIRMAEFGSCHRNEPSGSLHGLMRVRNFTQDDAHIFCTREQVRSEINDCIKMIYDLYSTFHFKKILVKLSTRPEKRIGTDSLWNESEKDLSDMLIENHLSFEYQSGEGAFYGPKIEFILQDSLDRNWQCGTIQLDFYLPLRLSSFYINEKNEKKVPVIIHRAILGSIERFIGILIEECSGNLPTWLSPVQVVIISITDISSGYVKELFKKFSDVNIRIECDLRNEKIGFKIREHTLRRIPYILICGEKESSSKKISVRNRQGHNFGMIDVDFFIKKLQKEIITRNFYQMEE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.