PharMolix/UniProtQA huggingface dataset:
Protein: LSRR_ECOLI
Sequence: MTINDSAISEQGMCEEEQVARIAWFYYHDGLTQSEISDRLGLTRLKVSRLLEKGHQSGIIRVQINSRFEGCLEYETQLRRQFSLQHVRVIPGLADADVGGRLGIGAAHMLMSLLQPQQMLAIGFGEATMNTLQRLSGFISSQQIRLVTLSGGVGSYMTGIGQLNAACSVNIIPAPLRASSADIARTLKNENCVKDVLLAAQAADVAIVGIGAVSQQDDATIIRSGYISQGEQLMIGRKGAVGDILGYFFDAKGDVVTNIKIHNELIGLPLSALKTIPVRVGVAGGENKAEAIAAAMKGGYINALVTDQDTAAAILRS
What is the function of this protein?
Regulates transcription of many different genes.  In the absence of autoinducer 2 (AI-2), represses transcription of the lsrACDBFG operon and its own transcription.  In the presence of AI-2, LsrR is inactivated by binding phospho-AI-2, leading to the transcription of the lsr genes.
What are the official names of this protein?
Transcriptional regulator LsrR.
What is the protein family that this protein belongs to?
Belongs to the SorC transcriptional regulatory family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AURKB_DROME
Sequence: MTLSRAKHANRNHLPHLLAKVPEEHQEPIKNMCLKMMSHDAYGQPYDWSPRDFEMGAHLGRGKFGRVYLARERHSHYLVAMKVMFKEELRKGCVQRQVLREIEIQSRLKHPHILRLLTWFHDESRIYLALEIASEGELFKHLRGAPNHRFDEPRSAKYTYQVANALNYCHLNNVIHRDLKPENILLTSTDDLKLADFGWSAHTPNNKRRTLCGTLDYLPPEMVDGNSYDDSVDQWCLGILCYEFVVGCPPFESNSTESTYSKIRRMEISYPSHLSKGCKELIGGLLRKESKGRITLVDVMTHYWVKAGMAERELQLQKRERGKENTARN
What is the function of this protein?
Serine/threonine-protein kinase which mediates both meiotic and mitotic chromosome segregation.  Required for histone H3 'Ser-10' phosphorylation.  Phosphorylates mei-S332 within residues 124-126 and stabilizes its association with centromeres during meiosis.
What are the official names of this protein?
Aurora kinase B, IPL1/Aurora-like protein kinase, Serine/threonine-protein kinase Ial, Serine/threonine-protein kinase aurora-B.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
What are the subcellular locations of this protein?
Chromosome. Cytoplasm, cytoskeleton. Midbody. Note=Meiotic and mitotic chromosomes. During each division, relocates to the midbody microtubules.
Protein: NEMA3_RAMPS
Sequence: GCIKTGSGCTLSKGCCTKNCGWNFKCNPPNQ
What is the function of this protein?
Toxin with similar potency against both insect and mammalian sodium channels (Nav) (PubMed:34445875).  It inhibits inactivation of most Nav tested (B. germanica (BgNav1); EC(50)=97. 5 nM, hNav1. 1/SCN1A; EC(50)=125. 8 nM, rNav1. 2/SCN2A; EC(50)=137. 8 nM, rNav1. 3/SCN3A; EC(50)=138. 9 nM, rNav1. 4/SCN4A; EC(50)=150. 2 nM, hNav1. 5/SCN5A; EC(50)=108. 4 nM, mNav1. 6/SCN8A; EC(50)=92. 8 nM, hNav1. 9/SCN9A; EC(50)=102. 2 nM) (PubMed:34445875).  1 uM is enough to completely inhibits the inactivation, resulting in sustained non-inactivating currents (By similarity).  In addition, the toxin significantly enhances the recovery from inactivation, and the open state is not required for the toxin to interact with the channel (By similarity).  In vivo, injection into brine shrimp (Artemia salina) stops movement or causes death after 24 hours (EC(50)=4. 7 uM) (PubMed:34445875).
What are the official names of this protein?
Nemertide alpha-3.
What is the protein family that this protein belongs to?
Belongs to the nemertide family.
What are the subcellular locations of this protein?
Secreted.
Protein: RBOHH_ARATH
Sequence: MKSNTPTEDSTKWMLESVEIDSMGESSSKEPEINLNKNEGGLKKNASRNLGVGSIIRTLSVSNWRKSGNLGSPSTRKSGNLGPPTNAVPKKTGPQRVERTTSSAARGLQSLRFLDRTVTGRERDAWRSIENRFNQFSVDGKLPKEKFGVCIGMGDTMEFAAEVYEALGRRRQIETENGIDKEQLKLFWEDMIKKDLDCRLQIFFDMCDKNGDGKLTEEEVKEVIVLSASANRLGNLKKNAAAYASLIMEELDPDHKGYIEMWQLEILLTGMVTNADTEKMKKSQTLTRAMIPERYRTPMSKYVSVTAELMHENWKKLWVLALWAIINVYLFMWKYEEFMRNPLYNITGRCVCAAKGAAETLKLNMALILVPVCRKTLTILRSTFLNRVVPFDDNINFHKVIAYMIAFQALLHTALHIFCNYPRLSSCSYDVFLTYAGAALGNTQPSYLGLMLTSVSITGVLMIFFMGFSFTLAMHYFRRNIVKLPKPFNVLAGFNAFWYAHHLLVLAYILLIIHGYYLIIEKPWYQKTTWMYLAVPMLFYASERLFSRLLQEHSHRVNVIKAIVYSGNVLALYVTKPPGFKYKSGMYMFVKCPDLSKFEWHPFSITSAPGDDYLSVHIRALGDWTTELRSRFAKTCEPTQAAAKPKPNSLMRMETRAAGVNPHIEESQVLFPKIFIKGPYGAPAQNYQKFDILLLVGLGIGATPFISILKDMLNHLKPGIPRSGQKYEGSVGGESIGGDSVSGGGGKKFPQRAYFFWVTREQASFDWFKGVMDDIAEYDKTHVIEMHNYLTSMYEAGDARSALIAMVQKLQHAKNGVDIVSESRIRTHFARPNWRKVFSELSSKHEACRIGVFYCGSPTLVRPLKELCQEFSLESSTRFTFHKENF
What is the function of this protein?
Calcium-dependent NADPH oxidase that generates superoxide.
What are the official names of this protein?
Putative respiratory burst oxidase homolog protein H, NADPH oxidase RBOHH, AtRBOHH.
What is the protein family that this protein belongs to?
Belongs to the RBOH (TC 5.B.1.3) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y863_METTH
Sequence: MSGALKENSGKPSEVEYTHFKDLQALEMERGRLYETIVVTWDDSMVGNAAPIGVLCTGDDTVTLYLYQGTRTVENVLNNGRFTVNVTLDPLIFTDSTLGDLEEDMFSHYRDFLHLRGADAFFTAEVVSVKKLVKRDRFGESELHVVKARAGDVMRAESFRMALNRGIYAVIESLIAYTRAEFSDPLVLRERIAEMNRVARKVGGPREKEAMRRIIQALESKIS
What are the official names of this protein?
Uncharacterized protein MTH_863.
What is the protein family that this protein belongs to?
To M.jannaschii MJ1453.
Protein: ANMK_ALBFT
Sequence: MSDLYIGLMSGTSLDGVDGVVVDFSGAHLRVLAHVNAPLSTALTHELLALNSPGTNELHRAALAANALVRVYAHVVAQLLELADIEHSAVAAIGAHGQTVRHQPQSFDGTGYTLQLNNPALLAELTGMDVVADFRSRDVAAGGQGAPLVPAFHQSAFGQPDQTLAVLNLGGMSNLTVLGPCPATESPAGVLDADPPSCFHSHDVLGFDCGPGNALMDTWCLQHIGQPFDADGAWAAAGRVHGELLAALLDEPYFAQSAPKSTGRDLFNSGWLTWKLEKFSSVAPVDVQATLTELTASVCATCVKRYGSESSTLIVCGGGAFNSHLMVRLQALLPRLKVISSQARGLPPLQVEAAAFAWLARNTLLRKTSSLEKVTGASGARILGAIYPA
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: SNF2_YEAST
Sequence: MNIPQRQFSNEEVNRCYLRWQHLRNEHGMNAPSVPEFIYLTKVLQFAAKQRQELQMQRQQQGISGSQQNIVPNSSDQAELPNNASSHISASASPHLAPNMQLNGNETFSTSAHQSPIMQTQMPLNSNGGNNMLPQRQSSVGSLNATNFSPTPANNGENAAEKPDNSNHNNLNLNNSELQPQNRSLQEHNIQDSNVMPGSQINSPMPQQAQMQQAQFQAQQAQQAQQAQQAQQAQARLQQGRRLPMTMFTAEQSELLKAQITSLKCLVNRKPIPFEFQAVIQKSINHPPDFKRMLLSLSEFARRRQPTDQNNQSNLNGGNNTQQPGTNSHYNNTNTDNVSGLTRNAPLDSKDENFASVSPAGPSSVHNAKNGTLDKNSQTVSGTPITQTESKKEENETISNVAKTAPNSNKTHTEQNNPPKPQKPVPLNVLQDQYKEGIKVVDIDDPDMMVDSFTMPNISHSNIDYQTLLANSDHAKFTIEPGVLPVGIDTHTATDIYQTLIALNLDTTVNDCLDKLLNDECTESTRENALYDYYALQLLPLQKAVRGHVLQFEWHQNSLLTNTHPNFLSKIRNINVQDALLTNQLYKNHELLKLERKKTEAVARLKSMNKSAINQYNRRQDKKNKRLKFGHRLIATHTNLERDEQKRAEKKAKERLQALKANDEEAYIKLLDQTKDTRITHLLRQTNAFLDSLTRAVKDQQKYTKEMIDSHIKEASEEVDDLSMVPKMKDEEYDDDDDNSNVDYYNVAHRIKEDIKKQPSILVGGTLKDYQIKGLQWMVSLFNNHLNGILADEMGLGKTIQTISLLTYLYEMKNIRGPYLVIVPLSTLSNWSSEFAKWAPTLRTISFKGSPNERKAKQAKIRAGEFDVVLTTFEYIIKERALLSKVKWVHMIIDEGHRMKNAQSKLSLTLNTHYHADYRLILTGTPLQNNLPELWALLNFVLPKIFNSVKSFDEWFNTPFANTGGQDKIELSEEETLLVIRRLHKVLRPFLLRRLKKDVEKELPDKVEKVVKCKMSALQQIMYQQMLKYRRLFIGDQNNKKMVGLRGFNNQIMQLKKICNHPFVFEEVEDQINPTRETNDDIWRVAGKFELLDRILPKLKATGHRVLIFFQMTQIMDIMEDFLRYINIKYLRLDGHTKSDERSELLRLFNAPDSEYLCFILSTRAGGLGLNLQTADTVIIFDTDWNPHQDLQAQDRAHRIGQKNEVRILRLITTNSVEEVILERAYKKLDIDGKVIQAGKFDNKSTSEEQEALLRSLLDAEEERRKKRESGVEEEEELKDSEINEILARNDEEMAVLTRMDEDRSKKEEELGVKSRLLEKSELPDIYSRDIGAELKREESESAAVYNGRGARERKTATYNDNMSEEQWLRQFEVSDDEKNDKQARKQRTKKEDKSEAIDGNGEIKGENIDADNDGPRINNISAEDRADTDLAMNDDDFLSKKRKAGRPRGRPKKVKLEGSENSEPPALESSPVTGDNSPSEDFMDIPKPRTAGKTSVKSARTSTRGRGRGRGRGRGRGRGRGRPPKARNGLDYVRTPAAATSPIDIREKVAKQALDLYHFALNYENEAGRKLSDIFLSKPSKALYPDYYMIIKYPVAFDNINTHIETLAYNSLKETLQDFHLIFSNARIYNTEGSVVYEDSLELEKVVTKKYCEIMGDNSQLDFTEFDEQYGTRPLVLPPVVTSSVAESFTDEADSSMTEASV
What is the function of this protein?
Involved in transcriptional activation.  Catalytic component of the SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes.  It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors.
What are the official names of this protein?
Transcription regulatory protein SNF2, ATP-dependent helicase SNF2, Regulatory protein GAM1, Regulatory protein SWI2, SWI/SNF complex component SNF2, Transcription factor TYE3.
What are the subcellular locations of this protein?
Nucleus.
Protein: PTH_ECO8A
Sequence: MTIKLIVGLANPGAEYAATRHNAGAWFVDLLAERLRAPLREEAKFFGYTSRVTLGGEDVRLLVPTTFMNLSGKAVAAMASFFRINPDEILVAHDELDLPPGVAKFKLGGGHGGHNGLKDIISKLGNNPNFHRLRIGIGHPGDKNKVVGFVLGKPPVSEQKLIDEAIDEAARCTEMWFTDGLTKATNRLHAFKAQ
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXB_SHEPC
Sequence: MKILVDENMPYVEPLFGDLGEIIPVNGRTLTAAQVRDADVLLVRSVTKVNAELLSDNHQLKFVGSATIGTDHVDLAYLGERNIPFSNAPGCNATAVGEFAFIAMLELAQRFDSPLKGKVVGIVGAGNTGTATAKCLQAYGIKVLLNDPIKEKQGDPRSFVSLETIMAQADIISLHVPITRTGEHKTKHLFDEARLTALKPNTWLVNCCRGDVIDNKALVRVKRQRDDLKLVLDVWEGEPTPMPELVPLAEFATPHIAGYSLEGKARGTFMLYQKLCQLLNIAADKSLLDLLPSFNIKAVELATAPDEKALLQLARFVYDLRDDDKMFRNIFLNENGFDTMRKNHRHRREFSALALAYDRQLEVDWLSNLGFSGVGQ
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RTEL1_BOVIN
Sequence: MPKITLKGVTVDFPFQPYKCQEEYMSKVLECLQEKVNGILESPTGTGKTLCLLCSTLAWREHLRDAVSARRIAERASGELFPDRTLASWGNAIPEGDVPACYTDIPKIIYASRTHSQLTQVISELRNTSYRPRVCVLGSREQLCIHPEVKKQESNHMQVHLCRRKVASRSCHFYNNVEEKSLEQELATPILDIEDLVRSGTKHKLCPYYLSRNLKQQADIIFMPYNYLLDAKSRRAHGIDLKGTVVIFDEAHNVEKMCEEAASFDLTPHDVASELDVIDRVLEERTKVAQQAELHPEFSADSARSGLNLEPEDLAKLKMILLRLEGAIDAVELPGDNSGVTKPGSYIFELFAEAQITFQTKGCILDSLDQLIQHLAGRAGLFTNTAGLQKLVDIIQIVFSVDSAEGDPGPMVGLASQSYKVHIHLDAGHRRTAQRSDVWNTTAARKPGKVLSYWCFSPGHSMRELVRQGVRTLILTSGTLAPMASFSLEMQIPFPVCLENPHVINQHQIWVGVIPKGPDGAQLSSAFDRRFSDECLSSLGKVLSNISRVVPHGLLVFFPSYPVMEKSLEFWRARDFTRKLEVRKPLFVEPRSKGGFSEVMEAFYARVAAPESSGAIFLAVCRGKASEGLDFADVNGRGVIVTGLPYPPRMDPRVLLKMQFLDEMKAQSGAGGQFLSGHDWYRQQASRAVNQAIGRVIRHRHDYGAVFLCDHRFAHADTRAQLPSWVRPHVKVYDSFGHVIRDVAQFFRVAQKTMPEPAPRAAAPSLGEGGGIVSVSVSPGPLPTRKAMSLDVHVPSLRQRHTGSPVTKDTEGSLCVEYEQEPVRAQRRPAGLLAALGHNEQLAEGPGDEALPVEEACGCPTLLGPREKRPAEEQRGRRRKVRLVGSSEVPAASTDTGRAKLFMVAVKQALSQASFDTFTQALRDYKSSDDLEALVARLSPLFAEDPKKHSLLQGFYQFVRPHHKQQFEEVCLQLTGQGCSSPHKHGHPQRQGAQLALDSSGRKESDPKLTVSQGATRQLDPCEQLNQGRPHLASGPFPAGDLNCSLHKGSRAPGAEKQHPSTVSAYLADVRRTLGAAGYSQLLTALTTYKQDDDFEKVVAVVAALTTEKPEDLPLLQRFGMFVRPHHKQRFRQMCVDLSGPGTQAPGPQEGGPAMPSDPVCEAPSPGPRKTQSKISSFLRCQACWRQHLQVSRKCPGCCAATRKQTLAQVFWPEPQ
What is the function of this protein?
ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability.  Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis.  Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates.  Also disassembles T loops and prevents telomere fragility by counteracting telomeric G4-DNA structures, which together ensure the dynamics and stability of the telomere.
What are the official names of this protein?
Regulator of telomere elongation helicase 1.
What is the protein family that this protein belongs to?
Belongs to the helicase family. RAD3/XPD subfamily.
What are the subcellular locations of this protein?
Nucleus. Note=Colocalizes with PCNA within the replication foci in S-phase cells.
Protein: SELO_ECOHS
Sequence: MTLSFVTRWRDELPETYTALSPTPLNNARLIWHNTELANTLSIPSSLFKNGAGVWGGEALLPGMSPLAQVYSGHQFGVWAGQLGDGRGILLGEQLLADGTTMDWHLKGAGLTPYSRMGDGRAVLRSTIRESLASEAMHYLGIPTTRALSIVTSDSPVYRETAEPGAMLMRVAPSHLRFGHFEHFYYRRESEKVRQLADFAIRHYWSHLEDDEDKYRLWFSDVVARTASLIAQWQTVGFAHGVMNTDNMSLLGLTLDYGPFGFLDDYEPGFICNHSDHQGRYSFDNQPAVALWNLQRLAQTLSPFVAVDALNEALDSYQQVLLTHYGERMRQKLGFMTEQKEDNALLNELFSLMARERSDYTRTFRMLSLTEQHSAASPLRDEFIDRAAFDDWFARYRGRLQQDEVSDSERQQLMQSVNPALVLRNWLAQRAIEAAEKGDMTELHRLHEALRNPFSDRDDDYVSRPPDWGKRLEVSCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: RS8_ACIF5
Sequence: MSVTDPIADMLTRIRNAQQVNKAKVRMPASKLKRAIARVLVEEGYIQEVKEDVANGHPVLDLTLKYYAGAGVIAEIRRVSRPGVRVYRGAEDLPRVRDGFGIAIISTSQGIMTDRAARSAGIGGEVLCVVS
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: TRUD_THEKO
Sequence: MDYREFFSQFKHLSEKPGIGGKIKIYPEDFIVIEEPIPSIFEGRKYAIFLLKKRNWETMAAVKEIAKRAGINYREIGFAGTKDRHAVTYQYISVPAEARERVEQVSIRDIELRFVSYGRFIKLGHLLGNRFRIIVRDVSEDAFDRTKEIVRELREKGGFPNYFGYQRFGERRVVNHIIGKLLLQGDFEGAARLFLGAHDGSMEGDEARKNFWETGDVERALEEFPGFLRYERTLLHRYKDTGNWKRAFLSLPLPIMRIFIHAYQSYLFNLYLSRRIEEGLPLNEPLVGDIVVQVKGGIPYRDRTYRVTETNLEFVREKVRKNQAMVSGPLFGFAMRRAKGLPGELEKEILEEEGLSLETFRRLPKPMAEPGGRRELLLRPMGMAYGYIQEEGMCFRFFLPKGTYATSVLREIMKDH
What is the function of this protein?
Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
Probable tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: RL34_UREPA
Sequence: MKRTFQPNNRKRAKVHGFRARMKTKNGRNVLARRRLKGRHSLTVSSEK
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: LEPA_ECOL5
Sequence: MKNIRNFSIIAHIDHGKSTLSDRIIQICGGLSDREMEAQVLDSMDLERERGITIKAQSVTLDYKASDGETYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAGQGVEAQTLANCYTAMEMDLEVVPVLNKIDLPAADPERVAEEIEDIVGIDATDAVRCSAKTGVGVQDVLERLVRDIPPPEGDPEGPLQALIIDSWFDNYLGVVSLIRIKNGTLRKGDKVKVMSTGQTYNADRLGIFTPKQVDRTELKCGEVGWLVCAIKDIHGAPVGDTLTLARNPAEKALPGFKKVKPQVYAGLFPVSSDDYEAFRDALGKLSLNDASLFYEPESSSALGFGFRCGFLGLLHMEIIQERLEREYDLDLITTAPTVVYEVETTSREVIYVDSPSKLPAVNNIYELREPIAECHMLLPQAYLGNVITLCVEKRGVQTNMVYHGNQVALTYEIPMAEVVLDFFDRLKSTSRGYASLDYNFKRFQASDMVRVDVLINGERVDALALITHRDNSQNRGRELVEKMKDLIPRQQFDIAIQAAIGTHIIARSTVKQLRKNVLAKCYGGDISRKKKLLQKQKEGKKRMKQIGNVELPQEAFLAILHVGKDNK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: AR2BP_DANRE
Sequence: MVDMQSLDEEDFSVSKSSDADAEFDIVIGNIEDIIMEDEFQHLQQSFMEKYYLEFDDSEENKLSYTPIFNEYIEILEKHLEQQLVERIPGFNMDAFTHSLKQHKDEVSGDILDMLLTFTDFMAFKEMFTDYRAEKEGRGLDLSTGLVVKSLNSSSASPLTPSMASQSI
What is the function of this protein?
Plays a role as an effector of the ADP-ribosylation factor-like protein 2, ARL2.
What are the official names of this protein?
ADP-ribosylation factor-like protein 2-binding protein, ARF-like 2-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ARL2BP family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, cilium basal body. Note=Detected in the midbody matrix. Not detected in the Golgi, nucleus and on the mitotic spindle. Centrosome-associated throughout the cell cycle. Not detected to interphase microtubules. The complex formed with ARL2BP, ARL2 and SLC25A4 is expressed in mitochondria (By similarity).
Protein: BLE_STRHI
Sequence: MAKLTSAVPVLTARDVAGAVEFWTDRLGFSRDFVEDDFAGVVRDDVTLFISAVQDQVVPDNTLAWVWVRGLDELYAEWSEVVSTNFRDASGPAMTEIGEQPWGREFALRDPAGNCVHFVAEEQD
What is the function of this protein?
Binding protein with a strong affinity to the bleomycin family of antibiotics.
What are the official names of this protein?
Bleomycin resistance protein, BRP, Phleomycin resistance protein.
What is the protein family that this protein belongs to?
Belongs to the bleomycin resistance protein family.
Protein: TM244_HUMAN
Sequence: MALQVRVAPSKVVLQKFLLCVILFYTVYYVSLSMGCVMFEVHELNVLAPFDFKTNPSWLNINYKVLLVSTEVTYFVCGLFFVPVVEEWVWDYAISVTILHVAITSTVMLEFPLTSHWWAALGISKLLV
What are the official names of this protein?
Transmembrane protein 244.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HFQ_PSEAE
Sequence: MSKGHSLQDPYLNTLRKERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVRLPSGDQPAEPGNA
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: CBIA_MAGMM
Sequence: MPYRIPRLFISATRKSSGKTFIAVGLTAALSARGLVVQPFKKGPDYIDPRWHSLAAGRECRNLDDFIMGRPKVLTSFVAHAQGADVAIIEGNLGLFDGQDLEGSDSSAALAKALGAPVLLVVDCKHLARSVAPLVCGHLHFPGGETIVGIILNNVATPRQEKRLREAIERFCPIPILGAIPRSAEIMIDERHLGLVPANEKQGAPHTVETMGRMMESHLDLDRLVALAATATPLALPDNPPALASKAPLVGGRPVRVGYAADQAFSFYYPDNLEALRQNGVELVPFSLLDEQPLPQVDGLYIGGGFPEMFMEHLQQNRATLETIRTRSELGMPIYAECGGLMVLSQRLIWAGKRVELAGALPIEITMHPKPQGYGYMKIHGTGALPWPPVDQEICCHEFHYSKVSKLGEGVRFAYQVTRGSGVDGWHDGILYHNIFASYAHIHVEGAPEWAPFLARFWRERGSFSQP
What is the function of this protein?
Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
What are the official names of this protein?
Cobyrinate a,c-diamide synthase, Cobyrinic acid a,c-diamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CbiA family.
Protein: QUEH_STAAM
Sequence: MINAEPIISKMKNQKINYDKVLKKLIGQWEREAIRPKILLHSCCAPCSTYTLEFLTQYADIAIYFANSNIHPKNEYLRRAKVQEQFVEDFNRKTGANVKYIEAPYEPHKFVKMVKDKELADEKEGGLRCTACFEMRLDIVAKAAVEHGYDYFGSAITLSPKKNAQLINELGMDVQKIYDVNYLPSDFKKSKGYERSIEMCNDYNIFRQCYCGCVFAAMQQGIDFKTVNKEAKAFLEQYPD
What is the function of this protein?
Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
What are the official names of this protein?
Epoxyqueuosine reductase QueH, Queuosine biosynthesis protein QueH.
What is the protein family that this protein belongs to?
Belongs to the QueH family.
Protein: RECX_MYCTU
Sequence: MTVSCPPPSTSEREEQARALCLRLLTARSRTRAELAGQLAKRGYPEDIGNRVLDRLAAVGLVDDTDFAEQWVQSRRANAAKSKRALAAELHAKGVDDDVITTVLGGIDAGAERGRAEKLVRARLRREVLIDDGTDEARVSRRLVAMLARRGYGQTLACEVVIAELAAERERRRV
What is the function of this protein?
Binds to RecA inhibiting ATP hydrolysis and the generation of heteroduplex DNA.  It might act as an anti-recombinase to quell inappropriate recombinational repair during normal DNA metabolism.  It is essential for cell survival.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_CLOTE
Sequence: MKKAIIGRKLGMTQIFDENNRVVPVTVVEAGPCTVVQKKSVEKDGYEAIQVGYGEIREKLVNKPLKGHFEKAGVGLSRMLREFKLENVSEYQVGQEIKVDIFEAGEKIDVTGTSKGKGYQGIIKRWNAHRGPMSHGSKFHRAVGSMGAASYPARTFKNKRMAGHMGNVKSTVLNLEVVKTIPEKNLILIKGGIPGPNKGYVIIRNSIKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: MNHF1_STAS1
Sequence: MNYNIILVIALVIVALSMLGMLARVIIGPSLADRVVALDAMGIQLMAIVALFSIFLGTKYMMVAILLIGILAFLGTAVFAKYMDKGKVIEHDNNDRH
What is the function of this protein?
Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.
What are the official names of this protein?
Na(+)/H(+) antiporter subunit F1, Mnh complex subunit F1.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PI42C_RAT
Sequence: MASSSVPPATAPAAAGGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSINELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFAIDDHDYLVSLTRSPPSETEGSDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVENEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTLKDMDFLNKNQKVYIGEEEKKVFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEGPVREEESEWDGDCNLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPEGGVFHGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFISNIFA
What is the function of this protein?
Phosphatidylinositol 5-phosphate 4-kinase with low enzymatic activity (PubMed:9685379).  May be a GTP sensor, has higher GTP-dependent kinase activity than ATP-dependent kinase activity (By similarity).  PIP4Ks negatively regulate insulin signaling through a catalytic-independent mechanism.  They interact with PIP5Ks and suppress PIP5K-mediated PtdIns(4,5)P2 synthesis and insulin-dependent conversion to PtdIns(3,4,5)P3 (By similarity).
What are the official names of this protein?
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma, Phosphatidylinositol 5-phosphate 4-kinase type II gamma, PI(5)P 4-kinase type II gamma, PIP4KII-gamma.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Cytoplasm.
Protein: TIBC_ECOH1
Sequence: MSTLKNTFFITPPDTPTQAGPENIFYDFNDGARVLLPEGKWHVRLLDADSENILFCCDVDKGWVTSSKKYFVRFRIQVFRQGEETPLLDETLKLKDRPVLISFPTGTLGDLLGWFPYAERFQSLHKCRLECTMSQDIIDLLAPQYPQIQFSTPDKPRTVAPYATYRVGLYFGGDTNNQPVDFRKVGFHRSAGYILGVDPREAPVRLDLSAPRVIQEPYVCIATQSTCQAKYWNNGTGWSEVIAHLKSLGYRVMCIDRDAHYGQGFVWNHIPWGAEDFTGKLPLQERVNLLRHASFFIGLPSGLSWLAWATRIPVVLISGFSLPNSEFYTPWRVFNSHGCYGCWDDTSLNFDHHDFLWCPRHKNTDRQFECTRLITGAQVNGVINKLHRSLTEQGVEATLKKGVSNE
What is the function of this protein?
Glycosylates the TibA adhesin.
What are the official names of this protein?
Glycosyltransferase TibC.