PharMolix/UniProtQA huggingface dataset:
Protein: GAG_RSVP
Sequence: MEAVIKVISSACKTYCGKTSPSKKEIGAMLSLLQKEGLLMSPSDLYSPGSWDPITAALSQRAMILGKSGELKTWGLVLGALKAAREEQVTSEQAKFWLGLGGGRVSPPGPECIEKPATERRIDKGEEVGETTVQRDAKMAPEETATPKTVGTSCYHCGTAIGCNCATASAPPPPYVGSGLYPSLAGVGEQQGQGGDTPPGAEQSRAEPGHAGQAPGPALTDWARVREELASTGPPVVAMPVVIKTEGPAWTPLEPKLITRLADTVRTKGLRSPITMAEVEALMSSPLLPHDVTNLMRVILGPAPYALWMDAWGVQLQTVIAAATRDPRHPANGQGRGERTNLNRLKGLADGMVGNPQGQAALLRPGELVAITASALQAFREVARLAEPAGPWADIMQGPSESFVDFANRLIKAVEGSDLPPSARAPVIIDCFRQKSQPDIQQLIRTAPSTLTTPGEIIKYVLDRQKTAPLTDQGIAAAMSSAIQPLIMAVVNRERDGQTGSGGRARGLCYTCGSPGHYQAQCPKKRKSGNSRERCQLCNGMGHNAKQCRKRDGNQGQRPGKGLSSGPWPGPEPPAVSLAMTMEHKDRPLVRVILTNTGSHPVKQRSVYITALLDSGADITIISEEDWPTDWPVMEAANPQIHGIGGGIPMRKSRDMIELGVINRDGSLERPLLLFPAVAMVRGSILGRDCLQGLGLRLTNL
What is the function of this protein?
Aspartyl protease that mediates proteolytic cleavages of Gag and Gag-Pol polyproteins during or shortly after the release of the virion from the plasma membrane.  Cleavages take place as an ordered, step-wise cascade to yield mature proteins.  This process is called maturation.  Displays maximal activity during the budding process just prior to particle release from the cell.
What are the official names of this protein?
Gag polyprotein.
What are the subcellular locations of this protein?
[Matrix protein p19]: Virion. SUBCELLULAR LOCATION: [Capsid protein p27, alternate cleaved 1]: Virion. SUBCELLULAR LOCATION: [Capsid protein p27, alternate cleaved 2]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p12]: Virion. SUBCELLULAR LOCATION: [Gag polyprotein]: Host nucleus, host nucleolus. Host nucleus, host nucleoplasm. Note=Shuttles between nucleoplasm and nucleolus.
Protein: LGT_STRPG
Sequence: MINPIALKCGPLAIHWYALCILSGLVLAVYLASKEAPKKGISSDAIFDFILIAFPLAIVGARIYYVIFEWSYYVKHLDEIIAIWNGGIAIYGGLITGALVLLAYCYNKVLNPIHFLDIAAPSVMVAQAIGRWGNFINQEAYGKAVSQLNYLPSFIQKQMFIEGSYRIPTFLYESLWNLLGFVIIMMWRRKPKSLLDGEIFAFYLIWYGSGRLVIEGMRTDSLMFLGIRISQYVSALLIIIGLIFVIKRRRQKGISYYQE
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYQ_POLAQ
Sequence: MSQDSKPTKSAAGAIAEPSNFLRQIIDHDLASGAFAQRTNLAGEAIPSIITRFPPEPNGYLHIGHAKSICLNFGLAADYNNQSGGARCNMRLDDTNPVKEDVEYADSILDAVKWLGFDWGTHLYHASDYFDRLYEFAEILIQNSKAYVDSQSADDIHTNRGNFGQVGKNSPYRERTPDENLQLFREMRDGKFKDGEHVLRLKIDMAHPNIVMRDPVVYRIRHTDHHRTGSKWCIYPLYDFTHCISDALENVSHSICTLEFENNRPLYDWIVNSLKELGVFKDPVPHQYEFARLNLTYTITSKRKLLQLVEEQHVEGWDDPRMPTIVGIRRRGYTPESIRLFCERIGVSKADSWIDMSTLDQALRDDLEARAPRATAVLKPLKLVVENFDAAHSEACSAPRHPHHPEWGNREFNFTKELWIEADDFMQEPVKGFFRLYPPIGDQPGSRVRLRHGFVVECTDFETDAKGNITQVNVNYFPDSKSGTPGSNNYKVKGNIHWISAAEAIPAEVRLYDHLFTDPHPDSGDKNFLDTINPHSKETIKAYLEPCMKDVKPEDRFQFERHGYFVADQNDSAPGKPVFNRTVGLKDSWK
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COPA_LEGPH
Sequence: MKHDHHQGHTHSGKGHACHHEHNSPKTQQASSKMEGPIVYTCPMHPEIRQSAPGHCPLCGMALEPETVTVSEVVSPEYLDMRRRFWIALMLTIPVVILEMGGHGLKHFISGNGSSWIQLLLATPVVLWGGWPFFKRGWQSLKTGQLNMFTLIAMGIGVAWIYSMVAVLWPGVFPHAFRSQEGVVAVYFEAAAVITTLVLLGQVLELKAREQTGSAIRALLKLVPESAHRIKEDGSEEEVSLDNVAVGDLLRVRPGEKIPVDGEVQEGRSFVDESMVTGEPIPVAKEASAKVIGATINQTGSFVMKALHVGSDTMLARIVQMVSDAQRSRAPIQRLADTVSGWFVPAVILVAVLSFIVWALLGPQPALSYGLIAAVSVLIIACPCALGLATPMSIMVGVGKGAQSGVLIKNAEALERMEKVNTLVVDKTGTLTEGHPKLTRIVTDDFVEDNALALAAALEHQSEHPLANAIVHAAKEKGLSLGSVEAFEAPTGKGVVGQVDGHHVAIGNARLMQEHGGDNAPLFEKADELRGKGASVMFMAVDGKTVALLVVEDPIKSSTPETILELQQSGIEIVMLTGDSKRTAEAVAGTLGIKKVVAEIMPEDKSRIVSELKDKGLIVAMAGDGVNDAPALAKADIGIAMGTGTDVAIESAGVTLLHGDLRGIAKARRLSESTMSNIRQNLFFAFIYNVLGVPLAAGVLYPLTGLLLSPMIAAAAMALSSVSVIINALRLKRVTL
What is the function of this protein?
Couples the hydrolysis of ATP with the export of copper.
What are the official names of this protein?
Copper-exporting P-type ATPase, Copper-exporting P-type ATPase A, Copper-transporting PIB-type ATPase, Cu(+) transport ATPase, Cu(+)-ATPase LpCopA, LpCopA.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KAD_LISIN
Sequence: MKLVLMGLPGAGKGTQAEQIVEKYNIPHISTGDMFRAAMKNNTELGKKAKSFMDNGDLVPDEVTNGIVRERLAEDDAKNGFLLDGFPRTVEQAEELENILSDLGTELDAVINIEVDKDVLMKRLTGRWICRTCGKTYHEIYNPPKVPGKCDLDGGELYQREDDKKETVENRLNVNMKQTKPLLDFYSEKGKLHSINGEQDINDVFVDVEKILASF
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGA_PELTS
Sequence: MNFQELILTLDNFWARQNCIIQQPYDVEKGAGTMNPATFLRALGPEPWRVAYVEPSRRPTDGRYGENPNRLQHYYQYQVILKPSPDDVLEVYLDSLKAIGIDPDEHDIRFVEDNWESPTLGAWGLGWEVWLDGMEVTQFTYFQQCGGIDCRPVSAEITYGLERLAMFIQGVDNVFDITWVDGITYGDVHHRGEVEHSHYNFELADTEMLFKLFDMYEREALRVVEKGFVLPAYDYVLKCSHTFNLLDARGAISVTERTGFIGRVRNLARTCAQAYIEQRQAMGYPLLKRKED
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_BREBN
Sequence: MPRVKGGIVTRRRHKKILKLAKGYFGSKHRLFKSANAQVMKSLLYAYRDRRQKKRDFRKLWITRINAQARMNGLSYSRLMHGLKVAGIEVNRKMLADLAVNDKAAFNELATVAKSKLNA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: CH034_HUMAN
Sequence: MSSPLASELSELAALRPGFRLSAPHARVAPRAATHARGRGRASHAGQPRLRSSCPGPSPGKRRVVPSGGAQPRVLPALSSRSHLFPMASHPQTRIQAYLEKNKIGPLFEELMTKLITETPDQPIPFLIDHLQSKQGNRGQLQRTLSGSAALWAESEKSESKGTRRDFRSYDKPWQLNAKKPKKSKSDLAVSNISPPSPDSKSLPRSVEHPKWNWRTKPQSRDFDELNHILQESKKLGKALENLSRSIAISDELDKETVTFNSSLLRPRVIGEWIGREENDADPLAAEMLQPPIPRSKNDQWESEDSGSSPAGSLKMEPKNKGLKQQQQQHKKLLAAMLSQDSFESIHSPTPSVTEEDIDNEDDAMELLEDLNDLRMEGVTTLVPSGSKFNQGRPTYPAEPQAKVTLNICSRCARLQGDNLEERTEESLPILHSPDEKIPDSFDSLPGTEEALMEEGDEFEKASKLTGPGEASSGVGHSLKNYMEEDESLKQLQVVHQPWILPSDTESEGVEAEQEKRSADLLLCVPCSSCPTLVYSGL
What are the official names of this protein?
Uncharacterized protein C8orf34, Protein VEST-1.
Protein: SDSL_MOUSE
Sequence: MEGALAERVGAEPFHRVTPLLESWALSQVAGMPVFLKYENVQIAGSFKIRGIGHFCQQMAKRGCRHLVCSSGGNAGIAAAYSARKLGIPVTIVLPEGTSVQVVRRLEGEGAEVQLTGKVWDEANVKAQELATRDGWVNVSPFDHPLIWEGHASLVRELKESLGTPPGAVVLAVGGGGLLAGVTAGLLEVGWQHVPIVAMETRGAHSFNSALQAGRPVTLPDITSVAKSLGAKTVAARTLECAKECEVLSEVVEDREAVSAVQRFLDDERMLVEPACGAALAAIYSGILWRLQAEGRLSSALASVVVIVCGGNNISSQQLQELKIQLGCS
What is the function of this protein?
Has low serine dehydratase and threonine dehydratase activity.
What are the official names of this protein?
Serine dehydratase-like, L-serine deaminase, L-serine dehydratase/L-threonine deaminase, L-threonine dehydratase, TDH, SDH.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family.
Protein: NDUB2_MOUSE
Sequence: MSALTRLVPFGRVGGRLLRGCRARAAGDSGVRHAGGGVHIQPRYREFPQLTRSQVIQGEFLSSLMWFWILWRFWHDSDAVLGHFSYPDPSQWTDEELGIPPDDED
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial, Complex I-AGGG, CI-AGGG, NADH-ubiquinone oxidoreductase AGGG subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFB2 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: GLPK_ALCBS
Sequence: MPYILSIDQGTTSSRAIVFDANGHACGQAQKEFRQYFPEDGWVEHDAMEIWNDTLAMCQQALRNARVEAQQLVAIGITNQRETTVLWDRETGDPLARAIVWQDRRTASTCEALRDQGHENQVRSKTGLLLDPYFSATKLAWLLDNVPNARQRAEAGELAFGTIDSWLLWQLTRGKVHATDATNASRTLLFNIHEQCWDEELLTLFNVPASVLPDVRDSAADFGTTCPELLGAAVPVTGIAGDQQAALVGQACFAPGMVKSTYGTGCFMVMNTGEAVESHNRLLTTVGYRLNGKTTYALEGSIFVAGAAIQWLRDGLHLIRDARETEALARRVGSAGGVYLVPAFTGLGAPWWDPHARGALMGLTRDTGIAEVVTAGLEAVCYQSRDLLDAMAADCGTRPTTLRVDGGMVVNNWLSQTLSDVLGVCVDRPVVTETTALGAAYLAGLGVGLYASLESIAEQWRCERGFSPALAEPERQKRYQGWRDAVARVCQTSRGAN
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: UPPP_STAAT
Sequence: MFIIELIKGIILGVVEGLTEFAPVSSTGHMILVDDMWLKSSEFLGSQSAFTFKIVIQLGSVFAAAWVFRERFLEILHIGKHKHVEGDNDQQRRSKPRRLNLLHVLVGMVPAGILGLLFDDFIEEHLFSVPTVMIGLFVGAIYMIIADKYSAKVKNPQTVDQISYFQAFVIGISQAVAMWPGFSRSGSTISTGVLMKLNHKAASDFTFIMAVPIMLAASGLSLLKHYQDIQIADIPFYILGFLAAFTVGLIAIKTFLHLINKIKLIPFAIYRIVLVIFIAILYFGFGIGKGI
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EFNB1_XENLA
Sequence: MEGLRRLLGLLLVLYRLCSALGKNLEPVTWNSQNPRFISGKGLVLYPEIGDRLDIICPKGDSSQPYEYYKLYMVRRDQLEACSTVIDPNVLVTCNQPGKEYRFTIKFQEFSPNYMGLEFRRNQDYYITSTSNSTLQGLENREGGVCQTRSMKIIMKVGQDPNAVPPEQLTTTRPSKEADNTGKIATFGPWNGPVENPGKSDTNLSDKPTAGGGVDGFFNSKIAVFAAIGAGCVIFILIIIFLVVLLIKIRKRHRKHTQQRAAALSLSTLASPKCSGNAGSEPSDIIIPLRTTENNYCPHYEKVSGDYGHPVYIVQEMPPQSPANIYYKV
What is the function of this protein?
Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development.  Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.  The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling (By similarity).  May have a role in the developing mesenchymal and nervous tissue.
What are the official names of this protein?
Ephrin-B1, ELK ligand, ELK-L, EPH-related receptor tyrosine kinase ligand 2, LERK-2, XlERK.
What is the protein family that this protein belongs to?
Belongs to the ephrin family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: KCNJ2_MOUSE
Sequence: MGSVRTNRYSIVSSEEDGMKLATMAVANGFGNGKSKVHTRQQCRSRFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVFWLIALLHGDLDTSKVSKACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFMVVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSHLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLYDLSKQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYYKVDYSRFHKTYEVPNTPLCSARDLAEKKYILSNANSFCYENEVALTSKEEEEDSENGVPESTSTDSPPGIDLHNQASVPLEPRPLRRESEI
What is the function of this protein?
Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues.  Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it.  Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages.  The inward rectification is mainly due to the blockage of outward current by internal magnesium.  Can be blocked by extracellular barium and cesium.
What are the official names of this protein?
Inward rectifier potassium channel 2, Inward rectifier K(+) channel Kir2.1, IRK-1, Potassium channel, inwardly rectifying subfamily J member 2.
What is the protein family that this protein belongs to?
Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ2 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Membrane; Lipid-anchor.
Protein: EIPR1_HUMAN
Sequence: MEDDAPVIYGLEFQARALTPQTAETDAIRFLVGTQSLKYDNQIHIIDFDDENNIINKNVLLHQAGEIWHISASPADRGVLTTCYNRTSDSKVLTCAAVWRMPKELESGSHESPDDSSSTAQTLELLCHLDNTAHGNMACVVWEPMGDGKKIISLADNHILLWDLQESSSQAVLASSASLEGKGQLKFTSGRWSPHHNCTQVATANDTTLRGWDTRSMSQIYCIENAHGQLVRDLDFNPNKQYYLASCGDDCKVKFWDTRNVTEPVKTLEEHSHWVWNVRYNHSHDQLVLTGSSDSRVILSNMVSISSEPFGHLVDDDDISDQEDHRSEEKSKEPLQDNVIATYEEHEDSVYAVDWSSADPWLFASLSYDGRLVINRVPRALKYHILL
What is the function of this protein?
Acts as a component of endosomal retrieval machinery that is involved in protein transport from early endosomes to either recycling endosomes or the trans-Golgi network (PubMed:27440922).  Mediates the recruitment of Golgi-associated retrograde protein (GARP) complex to the trans-Golgi network and controls early endosome-to-Golgi transport of internalized protein(PubMed:27440922).  Promotes the recycling of internalized transferrin receptor (TFRC) to the plasma membrane through interaction with endosome-associated recycling protein (EARP) complex (PubMed:27440922).  Controls proper insulin distribution and secretion, and retention of cargo in mature dense core vesicles (By similarity).  Required for the stability of the endosome-associated retrograde protein (EARP) complex subunits and for proper localization and association of EARP with membranes (By similarity).
What are the official names of this protein?
EARP and GARP complex-interacting protein 1, Endosome-associated recycling protein-interacting protein, Golgi-associated retrograde protein-interacting protein, Tumor-suppressing STF cDNA 1 protein, Tumor-suppressing subchromosomal transferable fragment candidate gene 1 protein.
What is the protein family that this protein belongs to?
Belongs to the WD repeat EIPR1 family.
Protein: SSPA_STAAR
Sequence: MKGKFLKVSSLFVATLTTATLVSSPAANALSSKAMDNHPQQTQTDKQQTPKIQKGGNLKPLEQRERANVILPNNDRHQITDTTNGHYAPVTYIQVEAPTGTFIASGVVVGKDTLLTNKHIVDATHGDPHALKAFASAINQDNYPNGGFTAEQITKYSGEGDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKPVATMWESKGKITYLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHWGGVPNQFNGAVFINENVRNFLKQNIEDINFANDDHPNNPDNPDNPNNPDNPNNPDNPNNPDNPDNPNNPDNPNNPDNPNNPDQPNNPNNPDNGDNNNSDNPDAA
What is the function of this protein?
Preferentially cleaves peptide bonds on the carboxyl-terminal side of aspartate and glutamate.  Along with other extracellular proteases it is involved in colonization and infection of human tissues.  Required for proteolytic maturation of thiol protease SspB and inactivation of SspC, an inhibitor of SspB.  It is the most important protease for degradation of fibronectin-binding protein (FnBP) and surface protein A, which are involved in adherence to host cells.  May also protect bacteria against host defense mechanism by cleaving the immunoglobulin classes IgG, IgA and IgM.  May be involved in the stability of secreted lipases (By similarity).
What are the official names of this protein?
Glutamyl endopeptidase, Endoproteinase Glu-C, Staphylococcal serine proteinase, V8 protease, V8 proteinase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1B family.
What are the subcellular locations of this protein?
Secreted.
Protein: THIC_GEOKA
Sequence: MENIRSFMSFPESRKVYIEGSRPDVRVPMREIALSPTKTPQGMVENKPVRVYDTTGPYTDPDFEPDVEKGLPPLRRRWIVERGDVEEMERSSVAIQRSLPFVRRPLRAKPGKTVTQMHYAKRGIITPEMEFVAIREQIDPEIVRQEVAAGRAIIPANINHPESEPMIIGRRFHVKINANIGNSAVSSSIEDEVEKLLWAVRWGADTVMDLSTGKHIHETREYIIRNSPVPVGTVPIYQALEKVGGVPEKLTWDVYRETLIEQAEQGVDYMTIHAGVRLHYIPLTANRTTGIVSRGGSIIAQWCLAHHEENFLYTHFEEICEILKQYDVAISLGDGLRPGSIADANDEAQFAELKTLGELTKIAWKHDVQVMIEGPGHIPMHKIRENVEREQEICHGAPFYTLGPLVTDIAPGYDHITSAIGAAIIGAYGTAMLCYVTPKEHLGLPNKEDVRAGVVAYKIAAHAADLAKGHPAAQQRDDALSKARFEFRWNDQFNLSLDPERAREYHDETLPAEAAKTAHFCSMCGPKFCSMNISHELQRKIKEEGMKEKAQQFIRQGSSLYQ
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: ASTE_ACIB3
Sequence: MQDFLALTLQGEQPATREGKQANFSWRWLGEGLLECTPHAQYDKAVVLSAGVHGNETAPIELLSHLCTDLFAGRLKLAVRLLLVLGNPYAMRQGKRYVHDDVNRMFCGGYKNLPVTEESKRAEVLEQTVATFFQESSSQAKRYHYDLHTAIRASLLPTFALFPYQTHGYDADLTASLEAADLDALVYHNALGKTFTHFTSENFKAASATLELGKALPFGQNDLSQFASIDEVIRNVVSEQALPVRNKPKIRVFQVSDSLIKKDEEFHMNLSAEAPNFSTFTKGEIIATQPSGNYVVEQDQVWILFPNPNVKIGLRAGLVLTETI
What is the function of this protein?
Transforms N(2)-succinylglutamate into succinate and glutamate.
What are the official names of this protein?
Succinylglutamate desuccinylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
Protein: TRHO_STRPZ
Sequence: MSEKIRVLLYYKYVSIENAQEYAAKHLEFCKSIGLKGRILIADEGINGTVSGDYETTQKYMDWVHSDERFADLWFKIDEENQQAFRKMFVRYKKEIVHLGLEDNNFDSDINPLETTGEYLNPKQFKEALLDEDTVVLDTRNDYEYDLGHFRGAIRPDIRNFRELPQWVRDNKDKFMEKRVVVYCTGGVRCEKFSGWMVREGFKDVGQLHGGIATYGKDPEVQGELWDGAMYVFDDRISVPINHVNPTVISKDYFDGTPCERYVNCANPFCNKQIFASEENETKYVRGCSPECRAHERNRYVQENGLSRQEWAERLEAIGESLPEFVGA
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: MSCL_BURCM
Sequence: MSIIKEFKEFAVKGNVMDLAVGVIIGGAFSKIVDSVVKDLIMPVIGVLTGGLDFSNKFVLLGTIPPTFKGNPDSFKDLQAAGVAAFGYGSFITVAINFVILAFIIFLMVKFINKLRKPEEAAPAATPEDIVLLREIRDSLKQR
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BIOD_BRUMB
Sequence: MNSRLIVTGTDTGIGKTVFSAALCHALGAVYWKPVQSGLEEETDSEIVARLAQASPQRILPEAWRLNTPASPHLSARLDGVEIRPEEMHIPATSLPLVIEGAGGLLVPLNDKTLFADLFAIWRIPAILCARAALGTINHTLLSLEAMRSRDIPVLGVAFIGEANEDTETTIAHLGRVKRLGRLPLLDDLSPEKLHHSFARNFHIDDFAGVAR
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA22_PIG
Sequence: ALWQFRSMIKCTIPGSDPLLDFNNYGCYCGLGGSGTPVDELDRCCETHDNCYRDAKNLDSCKFLVDNPYTNSYSYSCSNTEITCNSKNNACEAFICNCDRNAAICFSKAPYNKEHKNLDTKKYC
What is the function of this protein?
PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Phospholipase A2, minor isoenzyme, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: THOC5_RAT
Sequence: MSSESSKKRKPKVIRSDGTPTEGKRNRSDTEQEGRYYSEEAEVDLRDPGRDYELYKYTCQELQRLMAEIQDLKSKGSKDVAIEIEERRIQSCVHFMTLKKLNRLAHIRLKKGRDQTHEAKQKVDAYHLQLQNLLYEVMHLQKEITKCLEFKSKHEEIDLVSLEEFYSEAPPNISKAEITMGDPHQQTLARLDWELEQRKRLAEKYRECLSNKEKILKEIEVKKEYLSSLQPRLNSIMQASLPVQEYLFMPFDQAHKQYETARHLPPPLYVLFVQATAYGQACDKTLSVAIEGSVDEAKALFKPPEDSQDDESDSDAEEEQTTRRRPTLGVQLDDKRKEMLKRHPLSVLLDLKCKDNSVLHLTFFYLMNLNIMTVKAKVTTAMELITPISAGDLLSPDSVLSCLYPGDHGKKTPNPANQYQFDKVGILTLRDYVLELGHPYLWVQKLGGLHFPKEQPQHTVMADHSQSASHMETTMKLLKTRVQSRLALHKQFASLEHGIVPVTSECQYLFPAKVVSRLVKWMIMAHEDYMELHFTKDIVEAGLAGDTNLYYLALIERGTAKLQAAVVLNPGYSSIPPVFRLCLNWKGEKTNSNDDNIRAMESEVNVCYRELCGPRPSHQLLTNQLQRLCVLLDVYLETESHDDSVEGPKEFPQEKMCLRLFRGPSRMKPFKYNHPQGFFSHR
What is the function of this protein?
Regulates the expression of myeloid transcription factors CEBPA, CEBPB and GAB2 by enhancing the levels of phosphatidylinositol 3,4,5-trisphosphate.  May be involved in the differentiation of granulocytes and adipocytes.  Essential for hematopoietic primitive cell survival and plays an integral role in monocytic development (By similarity).
What are the official names of this protein?
THO complex subunit 5 homolog, Fms-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the THOC5 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between nucleus and cytoplasm.
Protein: ARGE_LEPBI
Sequence: MNFSKLVVRKMPAHLQKLTVKSKTKVKSLKKNEYYTIIPETAEQEKVKVAIPIGKQIRVRQGDFVKRGDQLDEGNFDPHDILAIKGPNALHEYLVSEVQEVYRLQGVHINDKHIEVVVRSMLRKVIITDSGDTSFVNQQQVDKFLFDEENDRVEKEGGSPAQGTPVLLGLTKASLNTESYFSAASFQETTKVLTDAAIKGKTDNLMGLKENVIIGHMIPAGTGMKKYRDIEVFKDLPGDLDWDLAIGGRGRRSFRTFRVGSCFHCHTLSTCCRRGRG
What are the official names of this protein?
Putative acetylornithine deacetylase, Acetylornithinase.
Protein: Y2173_STAAM
Sequence: MAMTVKKDNNEVRIQWRVADIKIPTSEIKNITQDQDIHAVPKLDSKDVSRIGSTFGKTNRVIIDTEDHEYIIYTQNDQKVYNELTK
What are the official names of this protein?
UPF0457 protein SAV2173.
What is the protein family that this protein belongs to?
Belongs to the UPF0457 family.
Protein: HCY_PALVU
Sequence: DVHSSDNAHKQHDVNHLLDKIYEPIKDEKLHNTAHTFNPVADTSIYGDDGAAAKTLMQKLNDHRLLEEHHWFSLFNTRQREELAMLFTVLNQCKEWDFLNNNAAFFRERMNEGEFVYALYVSVIHSKLGDGIVLPPLYQITPHMFTNSEVIDKAYSAKMTHKEGTFNMSFTGTQKNREQRVAYFGQDIGMNIHHVTWHMDFPFWWDDSYGYHLDRKGELFFWVHHQLTARFDAERFSNWMDPVDELHWDDIIHEGFAPHASYKYGGEFPTRPDNTHFKNVDGVARVRDMEITENRIRDAIAHGYITATDGHTIDIRQPNGIELLGDIIESSMYSSNPHYPGSLHNTAHGMLGRQGDPHGKFNMPPGVMEHFETATRDPSFFRLHKYMDNIFKEHTDSFPPYTHEDLEFPGVSVDNIAIEGHLTTFFDQFKYSLVNAVDSGENVEDVEIYANVHRLNHEEFTYDIEVRNHNEEDKFATVRIFLCPTEDNNGITLNLDEARWLCLELDKFWTKLGDGKNLIERSSKDSSVTVPDMPSFESLKKQADEAVNGGHDLDLSAYERSCGIPDRMLLPKSKPQGMEFNLYVAVTDGDKDTDGSHGDHDHHGTHAQCGIHGELYPDHRPLGYPLERRIPDDRVFDGVSNIKHALVKIVHDPELRA
What is the function of this protein?
Hemocyanins are copper-containing oxygen carriers occurring freely dissolved in the hemolymph of many mollusks and arthropods.
What are the official names of this protein?
Hemocyanin.
What is the protein family that this protein belongs to?
Belongs to the tyrosinase family. Hemocyanin subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space.