PharMolix/UniProtQA huggingface dataset:
Protein: RPOA_AGRRK
Sequence: MIQKNWQELIKPNKVEFTSSGRTKATLVAEPLERGFGLTLGNALRRVLLSSLRGAAVTAVQIDGVLHEFSSIPGVREDVTDIVLNIKEIAIKMDGDDAKRMVVRKQGPGVVTAGDIQTVGDIEILNPEHVICTLDEGAEIRMEFTVNNGKGYVPAERNRAEDAPIGLIPVDSLYSPVKKVSYKVENTREGQVLDYDKLSMSIETDGSITGEDAVAFAARILQDQLGVFVNFDEPQKEAEEEAVTELAFNPALLKKVDELELSVRSANCLKNDNIVYIGDLIQKTEAEMLRTPNFGRKSLNEIKEVLASMGLHLGMEVPAWPPENIEDLAKRYEDQY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: MRAY_STRR6
Sequence: MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQAKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVFRKINEGLNPKQKLALQLLGGVIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGFSNAVNLTDGVDGLASISVVISLFAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKPAKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKRIFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1548_ARCFU
Sequence: MARLLEEHGFETKTNVIVQGNCVEQEIDVVAERDGERYMIECKFHNIPVYTGLKEAMYTYARFLDVEKHGFTQPWIFTNTKFSEEAKKYAGCVGIKLTGWSYPEKEGIEVLLESKGLYPITILRIDKEVLDELVRAGLVFCRDVVSAGEEKLREIGLSAKKAREVIAEAKKVIG
What are the official names of this protein?
Uncharacterized protein AF_1548.
Protein: KAD2_YARLI
Sequence: MSTIEDLKATVERLAARVHELEASAKSKIAPEVPKSIRMVLIGPPGAGKGTQAPNLVEKYCACHLATGDMLRSQVQQQTPLGVEAKKIMDAGGLVSDDIMVNMIRSELENNSKCKNGFILDGFPRTIPQAEKLDEMLAEKKQPLEKAVELKIPDDLLVARITGRLVHPASGRSYHKVFNPPKKEMIDDITGEALVQRSDDNADALKKRLVSFHKQTEPIVGYYQKTGIWKGVDAAQDPKKVWGDILKCLGQ
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.  Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.
What are the official names of this protein?
Adenylate kinase, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate kinase cytosolic and mitochondrial, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family. AK2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Mitochondrion intermembrane space. Note=Predominantly mitochondrial.
Protein: RS4_BORA1
Sequence: MARYTGPKCKLSRREGTDLFLKSARRSLDSKCKLDSKPGQHGRTSGARTSDYGLQLREKQKLKRMYGVLEKQFRKYFAEAERRRGNTGETLIQLLESRLDNVVYRMGFGSTRAEARQLVSHRAIELNGHTADIASMLVKAGDVITVREGAKKQARIRESLDLAASIGIPQWVEVDSNKMTGTFKSPPDRADVARDVNESMVVELYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: GCSPB_THESQ
Sequence: MTIFERSKKGRKAFRLPESDIPEYSLPDRFLRSTPPKLPEVSEPDVVRHYTDLARKNYSVDLGIYPLGSCTMKYNPKLNEKAANLEGFREIHPYQPVETVQGSLRLMYELKEMLCEITGMDDMTLQPAAGAHGELTGMLIVREYFKNRGDTGRKKVLVPDSAHGTNPASASMVGFEVVEIKSKNGMVDVEDLRKLLDEEVAAVMLTNPNTLGLFEKDILKIAEMTHECGALLYYDGANLNAIMGKVRPGDMGFDIVHLNLHKTFSTPHGMGGPGSGPVGVKKHLVDFLPFPQVKKNGELYELFVPEKTIGRVRSFFGNFPVLVKAYTYILTMGRDGLERVSEMAVLNANYLKKKIEKFLEIPYNGFCMHEFVASAEKVFRETGVRTLDIAKRILDFGVHPPTVYFPLIVPEALMIEPTETENKETLDKYAEILERVVKEAYENPDALKNAPHNTPVRRVNEVLASKKPVFRWRG
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 2, Glycine cleavage system P-protein subunit 2, Glycine decarboxylase subunit 2, Glycine dehydrogenase (aminomethyl-transferring) subunit 2.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. C-terminal subunit subfamily.
Protein: SSRP_GLUOX
Sequence: MAGKKTKSGMISHGMAAQNRKGRFDYTILETTEAGIVLKGPEVKSLRLGRATITEAYAAERDGEIWLFNSYIPEYQGGVLSRFEPRAPRKLLMHRKQIAHFLGAVSRAGASLVPLDIHFNARGMAKVTLGLGQGRRKEDKRHAIAERDWKRDKARLVRSSGKDY
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: FOSL2_HUMAN
Sequence: MYQDYPGNFDTSSRGSSGSPAHAESYSSGGGGQQKFRVDMPGSGSAFIPTINAITTSQDLQWMVQPTVITSMSNPYPRSHPYSPLPGLASVPGHMALPRPGVIKTIGTTVGRRRRDEQLSPEEEEKRRIRRERNKLAAAKCRNRRRELTEKLQAETEELEEEKSGLQKEIAELQKEKEKLEFMLVAHGPVCKISPEERRSPPAPGLQPMRSGGGSVGAVVVKQEPLEEDSPSSSSAGLDKAQRSVIKPISIAGGFYGEEPLHTPIVVTSTPAVTPGTSNLVFTYPSVLEQESPASPSESCSKAHRRSSSSGDQSSDSLNSPTLLAL
What is the function of this protein?
Controls osteoclast survival and size (By similarity).  As a dimer with JUN, activates LIF transcription (By similarity).  Activates CEBPB transcription in PGE2-activated osteoblasts (By similarity).
What are the official names of this protein?
Fos-related antigen 2, FRA-2.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. Fos subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: GATA_METI4
Sequence: MKLFELSVKELRRLLVQKEVSPLEVVENLLCRIAEVDPKIFAYIYLNHERALEASKKADISLPLGGVPVAIKDNINVLGEPCRCASRILEGYLAPYDSTVIEKLKKAGAILLGRTNMDEFAMGSSTENSSVGITRNPWNTERVPGGSSGGSAAAVAAHEAFCALGSDTGGSIRQPAAFCGCVGLKPTYGRVSRYGLTAFASSLDQIGPITKTVEDAALLLEVISGFDPFDNTSEKLPVPRFSELLENRPLKDFVLGIPKEYFIEGIDGEVRQALSQVIGHYEKLGVKIEEVSLPHTPYAVATYYILATAEASANLARFDGIRYGKRAKNYNDLIDYYGKTRDEGFGSEVKRRILLGTYVLSSGYYDAYYLRALKVKEKIKQDFSLAFQKCQALLTPTSPFCAFRIGEKTSDPLQMYLADIFTIAVNLAGICALSIPCGRSTEGLPIGFQLIGPAWKEETILALGYIYQKTTGWVPPLPPLGGPTGGGGADGLPL
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: LTAS_STAAM
Sequence: MSSQKKKISLFAFFLLTVITITLKTYFSYYVDFSLGVKGLVQNLILLMNPYSLVALVLSVFLFFKGKKAFWFMFIGGFLLTFLLYANVVYFRFFSDFLTFSTLNQVGNVESMGGAVSASFKWYDFVYFIDTLVYLFILIFKTKWLDTKAFSKKFVPVVMAASVALFFLNLAFAETDRPELLTRTFDHKYLVKYLGPYNFTVYDGVKTIENNQQKALASEDDLTKVLNYTKQRQTEPNPEYYGVAKKKNIIKIHLESFQTFLINKKVNGKEVTPFLNKLSSGKEQFTYFPNFFHQTGQGKTSDSEFTMDNSLYGLPQGSAFSLKGDNTYQSLPAILDQKQGYKSDVMHGDYKTFWNRDQVYKHFGIDKFYDATYYDMSDKNVVNLGLKDKIFFKDSANYQAKMKSPFYSHLITLTNHYPFTLDEKDATIEKSNTGDATVDGYIQTARYLDEALEEYINDLKKKGLYDNSVIMIYGDHYGISENHNNAMEKLLGEKITPAKFTDLNRTGFWIKIPGKSGGINNEYAGQVDVMPTILHLAGIDTKNYLMFGTDLFSKGHNQVVPFRNGDFITKDYKYVNGKIYSNKNNELITTQPADFEKNKKQVEKDLEMSDNVLNGDLFRFYKNPDFKKVNPSKYKYETGPKANSKK
What is the function of this protein?
Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate, a reaction that presumably uses phosphatidylglycerol (PG) as substrate.  Is required for staphylococcal growth and cell division process (By similarity).
What are the official names of this protein?
Lipoteichoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the LTA synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [Processed glycerol phosphate lipoteichoic acid synthase]: Secreted.
Protein: CITE_LEUMC
Sequence: MNNERLRRTMMFVPGNNPAMVKDAGIFGADSIMFDLEDAVSLAEKDSARYLVYEALQTVDYGSSELVVRINGLDTPFYKNDIKAMVKAGIDVIRLPKVETAAMMHELESLITDAEKEFGRPVGTTHMMAAIESALGVVNAVEIANASDRMIGIALSAEDYTTDMKTHRYPDGQELLYARNVILHAARAAGIAAFDTVFTNLNDEEGFYRETQLIHQLGFDGKSLINPRQIEMVNKVYAPTEKEINNAQNVIAAIEEAKQKGSGVISMNGQMVDRPVVLRAQRVMKLANANHLVDSEGNYIEK
What is the function of this protein?
Represents a citryl-ACP lyase.
What are the official names of this protein?
Citrate lyase subunit beta, Citrase beta chain, Citrate (pro-3S)-lyase subunit beta, Citryl-CoA lyase subunit.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSHB_GEOOG
Sequence: MTPSRRLLLVHAHPDDETINNGATMARYVAEGAQVTLLTCTLGEEGEVLVPELELLAAEHADQLGGYRIGELRAAMEALGVADWRFLGGPGRYRDSGMMGTPANDEPRAFWNADLDEAVAHAVAVVREVRPQVVVTYDENGGYGHPDHIQAHRVAMRAVDAAADPAYRPDLGGAWEVAKVYWCCVPRSVLRQGIEALAALGEESPFASLDDVDDLPFAVPDELVAAAVDGRAHARRKDAAMRAHATQITVDGPFFALSNNLGQEVLGTEYYRLVRGERGTADGWEDDLFAGLPG
What is the function of this protein?
Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.
What are the official names of this protein?
1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase, GlcNAc-Ins deacetylase, N-acetyl-1-D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase.
What is the protein family that this protein belongs to?
Belongs to the MshB deacetylase family.
Protein: CA121_CONBU
Sequence: DGANAEATDNKPGVFERDEKKCCWNRACTRLVPCSK
What are the official names of this protein?
Conotoxin Bu21.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: AAK1_PIG
Sequence: MKKFFDSRREQGGSGLGSGSSGGGGSTSGLGSGYIGRVFGIGRQQVTVDEVLAEGGFAIVFLVRTSNGMKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINNVSSGDVWEVLILMDFCRGGQVVNLMNQRLQTGFTESEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQTEGVNAVEDEIKKYTTLSYRAPEMVNLYSGKIITTKADIWALGCLLYKLCYFTLPFGESQVAICDGNFTIPDNSRYSQDMHCLIRYMLEPDPDKRPDIYQVSFFSFKLLKKECPVPNVQNSPIPAKLPEPVKASEAAAKKTQPKARLTDPIPTTETSIAPRQRPKAGQTQPNPGILPIQPALTPRKRAMVQPPPQVAGSSNQPGLLASVPQPKTQAPPSQPLPQSQAKQPQAPPAPQQPPSAPAQGLPAQAQATPQHQQQLFLKQQPQPPQPQPQAQAPPVKSLKFYPFYPMCKGRQTVSSQFQAVHPAAQQPAIAQFPAVSQGSSQQQLIQNFYQQQQQQQQQQQLATTLHQQQLLTQQAALQQKTTVAAIQPPQAQPATASQPPPAQEPAQIQAPVRQQPKVQTTPPPAIQGQKLGSLTPPSSPKAQRAGHRRILSDVTHSAVFGVPASKSTQLLQAAAAEASLNKSKSATTTPSGSPRASQQNVYNPSEGSTWNPFDDDNFSKLTAEELLNKDFAKLGEGKHPEKLGGSAESLIPGFQPTQGDAFAASSFAAGTAEKRKGGQAVDSSLPLLSVSDPFIPLQVPDAPEKLIEGLKSPDTSLLLPDLLPMTDPFGSTSDAVIEKADVAVESLIPGLEPPVPQRLPSQTESVASNRTDSLTGEDALIDCSLLSNPTTDLLEEFAPIAISAPAHKAAEDSNLISGFDVPEGSDKVAEDEFDPIPVLITKNPQGGHSRNSSGSSESSLPNLARSLLLVDQLIDL
What is the function of this protein?
Regulates clathrin-mediated endocytosis by phosphorylating the AP2M1/mu2 subunit of the adaptor protein complex 2 (AP-2) which ensures high affinity binding of AP-2 to cargo membrane proteins during the initial stages of endocytosis (PubMed:11877457).  Preferentially, may phosphorylate substrates on threonine residues (By similarity).  Regulates phosphorylation of other AP-2 subunits as well as AP-2 localization and AP-2-mediated internalization of ligand complexes (By similarity).  Phosphorylates NUMB and regulates its cellular localization, promoting NUMB localization to endosomes (By similarity).  Binds to and stabilizes the activated form of NOTCH1, increases its localization in endosomes and regulates its transcriptional activity (By similarity).
What are the official names of this protein?
AP2-associated protein kinase 1, Adaptor-associated kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Membrane, clathrin-coated pit. Presynapse. Note=Active when found in clathrin- coated pits at the plasma membrane. In neuronal cells, enriched at presynaptic terminals. In non-neuronal cells, enriched at leading edge of migrating cells.
Protein: PATM_ASPCL
Sequence: MDMLRNRPVKGSLDHDPQLSADGTNTPAASDGSDQRSDVIEKTAQLSEPIADSIRRFFEIRKLDGPDGTGVVFENISVEGSGTGAQAAPTISSAARSAFGVLSPLQHRLAGQFSRPILSGFSGTIDAGEMLLVIGKPGSGCTTFLKTLSYMWDEYKDVHGDLTIGGHPIQESMVKRPQDIVFCAESDDHFPTLTVAETLRFAIRARCGPEASATEVDMMVAQLAKLVGLSQVMNTKVGDAYIRGVSGGERRRVSLAEALATCARLICLDNPTHGLDSSTALEFIETMREWTSQSRCVTAMSVYQASDAIMPYFDKVLVINSGRQVFYGRIGDAKAYFERLGFECLPTTTLSDFLNSMSADPEVRRVQDGKQHLVPRTSEEFEAVFHASTFYQDLQRSLETAKVEARTNPRPLVKARAFSLPLHHQIWYCAYRQFRIVTSDYSLWAVEPATIIVQSLVLGTLFRDQKRATQSLFIFASALFYSVLVPALQSMAEFGNGFAQRPLILKQKRYRICRPIAYALGLVTTDVVWKIAAICYNIPLYFLTGFQRTAGNFFTWFCIVYLEHLALSMFFRSVAIFSPNMHRAVLPVGIFFNMYVLYTGLYIPAPQMQVWLGWLRYLNPLYYAFESVMVNEFRDLSYQCSPSDLVPSGLGYTDMANQVCAVLGSRSGEESLSGMSYLEAQYGFGRSHLWRNVGINAAFFVFFALCSGIGMERLKTPAGRLATVFYKGRPSIRNSQADSESGAVHDDVPPDVSRQLSGDQHHLNANSERDKNHTLAWTGLCLDIETKDGTRRLLDNLNGWVKSGQLKALMGVSGAGKTTLLNTLAGRSSIGTLTGTLALNGQLLPKFFRSRMGYVQQQDIHLPTQSVREALQMTARLRRDESIPLEEKNAYVEKVIEWLDMEDIAEALVGVPGAGLNLEQRKRVSIGVEMASKPEILFLDEPTSGLDGQSAFSIVRLLRRLADSGQAIVCTIHQPAAELVEQFDELYLLSRGGKLVYDGPLGTHCDKAIEYFEQHSRACGQGENPAEYFLDAIGAGSRKEVQADWVGLWQQSQQSKDRERAEKALVPAEGQAPLAPARRSLYAVPFHVQLWVVVQRTWLYYWREPDYAMSKLWMSVGNALLNSLTYLQSPNTQRGAYNRVFSAFMSLIVGPPLGLQVQPRFVTLRDIFVHREREGFTYHWLAFVFAGIIVELPYTFLTSLVYWLLWYFPVGYFRTAPRAGYSFLMYELFAVFATSLAQMCASLMPNIEAAFAANGFFFMFCNTFAGTLSPKPVTPSGWRWYYKVSPLFYLGEGVTVDVLQDLPLRCAESEVSIFQPPNGTTCGQYAANFLQQATGFLLNTDSLSDCQYCRYRDGQSYYQQYGYDFANRYPNIGIFIGFIAFNFTMVLVMTYLTKIRR
What is the function of this protein?
ABC transporter; part of the gene cluster that mediates the biosynthesis of patulin, an acetate-derived tetraketide mycotoxin produced by several fungal species that shows antimicrobial properties against several bacteria (Probable).  May be involved in the secretion of E-ascladiol to be converted to patulin by the secreted patulin synthase patE (By similarity).
What are the official names of this protein?
ABC transporter patM, Patulin synthesis protein M.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: ADE_PSEPF
Sequence: MYDWLNALPKAELHLHLEGSLEPELLFALAERNKIALPWSDVETLRKAYAFNNLQEFLDLYYQGADVLRTSQDFYDLTWAYLLRCKEQNVIHTEPFFDPQTHTDRGIPFEVVLNGIAAALKDGEQQLGITSGLILSFLRHLSEDEAQKTLDQALPFRDAFVAVGLDSSEMGHPPSKFQRVFDRARHEGFLTVAHAGEEGPPEYIWEAIDLLKIQRIDHGVRAIEDERLMQRIIDEQIPLTVCPLSNTKLCVFDHMSQHNILDMLERGVKVTVNSDDPAYFGGYVTENFHALHEHLGMTQDQAKRLAQNSLDARLVKP
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenine to hypoxanthine.  Plays an important role in the purine salvage pathway and in nitrogen catabolism.
What are the official names of this protein?
Adenine deaminase, ADE, Adenine aminohydrolase, AAH.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
Protein: RPOZ_BURM7
Sequence: MARITVEDCLKQIPNRFELALAATYRARQLAQGHTPKIESRDKPTVVALREIAAGQVGVEMLKKVPA
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: SLAB3_TRIST
Sequence: MGRFISVSFGLLVVFLSLSGAGAGFCCPLGWSSYDLYCYKVFKQEMNWTDAEKFCTEQHTGSHLVSFHSSEEADFVVNMTYPILKLDFVWIGLSNVWNQCNSEWSDGTKLNYKDWSGESECIASKTIENQWWSRSCSRTHYVVCKFQA
What is the function of this protein?
Interferes with one step of hemostasis (modulation of platelet aggregation, or coagulation cascade, for example).
What are the official names of this protein?
Snaclec stejaggregin-A subunit beta-3.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: NU1M_PRIMA
Sequence: MFLMNILCLIIPILLAMAFLTLVERKILGYMQLRKGPNVVGPYGLLQPIADAIKLFIKEPLRPLTSSKTMFILAPTLAFSLALSMWIPMPMPHPLVNLNLGVLFILALSSLAVYSILWSGWASNSKYALIGALRAVAQTISYEVTLAIILLSIMMLNGSFTLSTLTTTQEHLWLIFPLWPLAMMWFISTLAETNRAPFDLTEGESELVSGFNVEYAAGPFALFFMAEYTNIIMMNALTTILFLGALHNPLFPELFTVNFVTKTLLLTVTFLWVRASYPRFRYDQLMHLLWKSFLPLTLALCMLHVSTPTMLAGIPPHM
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: IES1_YEAST
Sequence: MGKRVYDPIHDTFQLREDNSDETKADSPMQSVKSGSQEEASPSSIQSETETVTTKSIPVIHEIEIDDKNDDDSTQSEEENTNILLNFEPSTVPEATGASTATGPVTTNTVRRKPKESNASKYNRHLKKPDGEPFNRKDIQFSFMQELLMDKRQIFTNVLKPLYKNSIVPINIDGDKLSINVTDKEYDARTFVFNDKLTFAQLYVLTIATSIKCSKILRDKLLLDQQVAFSTCVLALLVNIGRLNTTINFYLEMTSQLRTFHSVPVLQLHANDPKLLQDTPRLKSILKNLPWGNEQLSLMETYKKVDQNDGEVDTVNKFNIINMLFSICDNSGLIDKRFLSKYVEVESKAQEQDMVDEQNEVKETEAENEKQESKAAYATTLFDILDYSKYEPKDRSNILIWLLYIHLETNLSQEEVEESVRFFNGLEDGAPAGKFILRCTERSYDTDPEDELEFGANQRIKRREFMSKMEEGRKRERTNVTEVKKPSIGGDKSEEDGEGEDDKSEETVEETRSLLTPTPILESSSPMTLNRKKVTPQLPKVTPAAPTETEEEITSAAIIDKNDLNLTPLKKYNSSATVNKVDKLISLDLNKHVSENGKTQEEFLADLKKSQVPNRLKRRDIGLIKIFNEFEDIPVASVLGIRGKKRKKFKDNLLGFETDFMKNLGASKKVLLNKIERAEIDDEEATAMFKLE
What is the function of this protein?
Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin-remodeling complex.
What are the official names of this protein?
Ino eighty subunit 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: NLP7_PLAVT
Sequence: MHLCALLIAAAGVLASVRANYVEIDAYTVKPFAQQKPSTDSERSALKYKPHLHVQAGCHPYPAVQRDGSLSAGFEWKEKNSQPCGRSPLGSQVYSRSNWYKEKWAIMYAWYFPKASNHIGRGVSGSRHYWLYAIVWTDDANPTNSSLLGVTLSAGIGLSKHTKLKSKHVIDGTTLKLKSHLSFWGRRLALKFTNKLGETQDLITWEQLPPEAQTALTLDYKLNTPLQDFRFEDLLKEAYPF
What is the function of this protein?
Secreted effector that acts as a pathogen-associated molecular pattern (PAMP) recognized by the plant immune system (PubMed:35152834).  Induces necrosis in Nicotiana benthamiana leaves and can induce Phytophthora capsici resistance in Nicotiana benthamiana (PubMed:35152834).  Also significantly improves disease resistance of Arabidopsis thaliana to Hyaloperonospora arabidopsidis (PubMed:35152834).  causes an inhibition of plant growth which is typically associated with enhanced immunity when over-expressed in Arabidopsis (PubMed:35152834).
What are the official names of this protein?
NLP effector protein 7, Nep1-like protein 7.
What is the protein family that this protein belongs to?
Belongs to the Necrosis inducing protein (NPP1) family.
Protein: YPK2_YEAST
Sequence: MHSWRISKFKLGRSKEDDGSSEDENEKSWGNGLFHFHHGEKHHDGSPKNHNHEHEHHIRKINTNETLPSSLSSPKLRNDASFKNPSGIGNDNSKASERKASQSSTETQGPSSESGLMTVKVYSGKDFTLPFPITSNSTILQKLLSSGILTSSSNDASEVAAIMRQLPRYKRVDQDSAGEGLIDRAFATKFIPSSILLPGSTNSSPLLYFTIEFDNSITTISPDMGTMEQPVFNKISTFDVTRKLRFLKIDVFARIPSLLLPSKNWQQEIGEQDEVLKEILKKINTNQDIHLDSFHLPLNLKIDSAAQIRLYNHHWISLERGYGKLNITVDYKPSKNKPLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCALDSLHKLDVIYRDLKPENILLDYQGHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQQPLLFPDGFDPAAKDLLIGLLSRDPSRRLGVNGTDEIRNHPFFKDISWKKLLLKGYIPPYKPIVKSEIDTANFDQEFTKEKPIDSVVDEYLSASIQKQFGGWTYIGDEQLGDSPSQGRSIS
What is the function of this protein?
May act as a downstream kinase in the sphingolipid-mediated signaling pathway.  Plays an essential role in the proliferation of yeast cells.  Involved in a signaling pathway, required for optimal cell wall integrity, that acts in parallel with the PKC1-SLT2-dependent pathway.  A substrate of TOR complex 2 (TORC2) and required for TORC2 to regulate spatial aspects of cell growth.  Phosphorylation of residue Thr-501 is indispensable for function.
What are the official names of this protein?
Serine/threonine-protein kinase YPK2/YKR2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: Y4865_PHOLL
Sequence: MGIDVAENTGEIYSNLAPREKLLAYGSVSLTDAELLAIFLRTGTRGLPVLRMAEFLLKEFGSLYHLLSADYDTFCSHKGMGLAKYAQLQAIAELAKRFFSSQFMHEDIMSSPSVTQEYLQNLLSGRDREIFVVLFLNNQNRVICHEEMFKGTINKVEVHPREIVRSAIKVNASSVILAHNHPSGHAEPSLADKIVTDKVIDACNLVGVKVLDHLVIGRQCCVSFAERGWI
What are the official names of this protein?
UPF0758 protein plu4865.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family. YicR subfamily.
Protein: NQRA_CHLTR
Sequence: MKIVVSRGLDLSLKGAPKESGFCGKVDPTYVSVDLRPFAPLPLGVKVTPEDQVTAGSPLAEYKLFSGVFITSPVDGEVVEIRRGNKRALLEIVIKKKPGISQTKFSYDLQSLTQKDLLEVFKKEGLFALFKQRPFDIPALPTQSPRDVFINLADNRPFTPSVEKHLSLFSSKEDGYYIFVVGVQAIAKLFGLKPHIISTDRLTLPTQDLVSIAHLHTIDGPFPSGSPSTHIHHIARIRNERDVVFTISFQEVLSIGHLFLKGFVLGQQIVALAGSALPPSQRKYLITAKGASFSDLLPKDIFSSDEITLISGDPLTGRLCKKEENPCLGMRDHTITLLPNPKTRESFSFLRLGWNKLTVTRTYLSGFFKRKRVFMDMDTNMHGEKRPIIDAEIYERVSAIPVPVALIIKALETQNFEEACRLGLLEVAPEDFALPTFIDPSKTEMFSIVKESLLRYAKENVVTSS
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit A, Na(+)-NQR subunit A, Na(+)-translocating NQR subunit A, NQR complex subunit A, NQR-1 subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrA family.