PharMolix/UniProtQA huggingface dataset:
Protein: THIC_ANADE
Sequence: MRADWIAKRRGQANVSQMHYARDGVVTEEMAFVAARERLEPELVRAEVARGRMVIPANVRHPELEPLAIGIEACCKINANIGNSAVTSNIDEELAKLRVCLKYGADTVMDLSTGGDIPQIREAILRASPIPVGTVPIYECLAHVKDVADLTPELMLEIIEAQAAQGVDYMTIHAGVLRDFIPLAAHRITGIVSRGGALMAQWMLANKAENPFFTHFEQICEIFKRYDVTFSLGDGLRPGCLADASDAAQFAELKALGDLTRKAWEHGVQVMVEGPGHVPLDQIPMNMEKERELCSEAPFYVLGPLVTDIAPGYDHITSAIGAAVAAQHGAAMLCYVTPAEHLGLPDIDDVREGIVAYKIAAHAADVARHRPGARDRDDALSRARYAFDWNKQFELSLDPDTARAKHDETLPHEAFKSAEFCSMCGPKFCSMKIHGHLAEAAAAQDEAANGAAAKPAGGLQVLP
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: ENO_BURL3
Sequence: MSAIVDIIGREILDSRGNPTVECDVLLESGTMGRAAVPSGASTGSREAIELRDGEAGRYNGKGVLKAVEHINTEISEAIMGLDASEQAFLDKTLLELDGTDNKSRLGANAMLAVSMAVAKAAAEEAGLPLYRYFGGSGAMQLPVPMMNIVNGGAHANNSLDIQEFMIVPVSQPTFREALRCGAEVFHALKKILSDRGMSTAVGDEGGFAPNFGSNDECLSTILQAIEKAGYRAGEDVLLALDCAASEFYHDGKYQLAGEGLQLSSAEFTDYLATLADKFPIVSIEDGMHESDWEGWKLLTDRLGKKVQLVGDDLFVTNTRILKEGIEKGIANSILIKINQIGTLTETFAAIEMAKRAGYTAVISHRSGETEDSTIADIAVGLNAGQIKTGSLSRSDRISKYNQLLRIEEDLGDIASYPGKSAFYNLR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RFCS1_PYRAE
Sequence: MAELFWFEKYRPRSFDEVVDLEEVKARLREFVKAGNMPHLLFYGPPGTGKTTMALVLARELYGEYWRENTLELNASDERGINVIRERVKEFARTAPVGKAPFKLVILDEADNMTSDAQQALRRIMEIYAQNTRFILLANYVSRIIDPIISRCAVFRFSPMPRSLMAERLKFIAKNEGVELREDAINMIYELSEGDMRKAINLLQVAAATNKVVDANAVASAAIAVRPADIIELFNLAISGDFVKAREKLRELMYLKGIAGADFIRAFQRELIRMPIDDDIKAEIAELLADVDYRLTQGADEEIQLTYLLTKLGAIGRRVKPATTQPRKK
What is the function of this protein?
Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.
What are the official names of this protein?
Replication factor C small subunit 1, RFC small subunit 1, Clamp loader small subunit 1.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family. RfcS subfamily.
Protein: QUEC_ACTP2
Sequence: MNSTPKAVVIFSGGQDSTTCLFQAIQEFGVENVEVVTFQYGQRHAIELEKAAWIAKDLGVKQTLIDTSVIKAITSNAMMEEHEIKQEGNTPNTFVDGRNALFLLYTAIYAKGQGIRTIFTGVCETDFSGYPDCRDVFVKSMNVTLNLAMDYNFNIRTPLMYLTKKQTWALADKLGAFDYIRQHTHTCYLGVEGGCHTCPSCVLREKGLNEYLSEKTSGQKNV
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: PUR7_LIMF3
Sequence: MEEKLLYAGKAKEMWTTEDEDQLRVVYLDQATQLNGKQKEHFAGKGAAAHAISDLVFHYLIDHGIETHFIKKLSATEDLVEKCAMVPLEFVTRNTVAGHFASRFGLEEGTALPQPVEENFYKDDELDDPFINESAAVALKMVTPAEFDRCWAICRQVDQLLTPLFEKAGMQLVDFKLEFGRRSRDNQIILADEFSPDNCRLWDTTTHHHLDKDVFRRNLADLTATYQEVYARLQAALKED
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: COX2_CANGA
Sequence: MLNLLNTLFLNVISNDVPTPYGIYFQDSATPNQEGILELHDNIMFYLFIILGLVSWMLFTIVKTYSKNPMAYKYIKHGQTIEIIWTMFPAVILLIIAFPSFILLYLCDEVISPAMTIKAIGYQWYWKYEYSDFINDNGETIEFESYVIPDDLLEEGQLRLLDTDTSVVVPVDTHIRFVVTGADVIHDFAIPSLGIKVDANPGRLNQVSALIQREGVFYGQCSELCGVNHAAMPIKIEAVSLPKFLEWLNEQ
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DIVIB_LACPL
Sequence: MAIFHKKPKEREHPEQLTPWERFQRDAAENHRAAQKSHHSWSGKRLRIGDKLPKLKSQRRRLLFKRVVILMGCFLIGAGVAGYFISPLSHVQTVTVHGNDQLSVTQVKTATKINPGVALWSVIGHDQRTTKRAERAQPQIGKVTTKLVGLNSVRVTVKEIRIAGYLSTGQHYRRILENGLILKVTYSQPGGGSPIYANFKSGHRLATMIAQYAKLPSAVKHNISEIKFAPNKANPERVHLYMNDGNEVYATISTFASKMAYYPGIVAKMKTKGVINLEVGAYSYPFKNQNN
What is the function of this protein?
Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.
What are the official names of this protein?
Cell division protein DivIB.
What is the protein family that this protein belongs to?
Belongs to the FtsQ/DivIB family. DivIB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: RS11B_SCHPO
Sequence: MATELVVQSERAFQKQPHIFQNAKKGAGRRWYKDVGLGFKTPAEAIYGEYVDKKCPFVGQVSIRGRILTGTVVSTKMHRTIIIRREYLHFIPKYNRYEKRHKNLAAHVSPAFRINEGDVVTVGQCRPLSKTVRFNVLRVVKHTEGPKQFGKF
What are the official names of this protein?
40S ribosomal protein S11-B.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: YDIB_ECOSM
Sequence: MNVTAKYELIGLMAYPIRHSLSPEMQNKALEKAGLPFTYMAFEVDNDSFPAAIEGLKALKMRGTGVSMPNKQLACEYVDELTPAAKLVGAINTIVNDDGYLRGYNTDGTGHIRAIKESGFDIKGKTMVLLGAGGASTAIGAQGAIEGLKEIKLFNRRDEFFDKALAFAQRVNENTDCVVTVTDLADQQAFAEALASADILTNGTKVGMKPLENESLVHDISLLHPGLLVTECVYNPHMTKLLQQAQQAGCKTIDGYGMLLWQGAEQFTLWTGKDFPLEYVKQVMGFGA
What is the function of this protein?
The actual biological function of YdiB remains unclear, nor is it known whether 3-dehydroshikimate or quinate represents the natural substrate.  Catalyzes the reversible NAD-dependent reduction of both 3-dehydroshikimate (DHSA) and 3-dehydroquinate to yield shikimate (SA) and quinate, respectively.  It can use both NAD or NADP for catalysis, however it has higher catalytic efficiency with NAD.
What are the official names of this protein?
Quinate/shikimate dehydrogenase, NAD-dependent shikimate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: SFGH1_ECOHS
Sequence: MELIEKHASFGGWQNVYRHYSQSLKCEMNVGVYLPPKAANEKLPVLYWLSGLTCNEQNFITKSGMQRYAAEHNIIVVAPDTSPRGSHVADADRYDLGQGAGFYLNATQAPWNEHYKMYDYIRNELPDLVMQHFPATTRKSISGHSMGGLGALVLALRNPDEYVSVSAFSPIVSPSQAPWGQQAFAAYLGENKDAWLDYDPVSLISQGQRVAEIMVDQGLSDDFYAEQLRTPNLEKICQEMNIKTLIRYHEGYDHSYYFVSSFIGEHIAYHANKLNMR
What is the function of this protein?
Serine hydrolase involved in the detoxification of formaldehyde.  Hydrolyzes S-formylglutathione to glutathione and formate (By similarity).
What are the official names of this protein?
S-formylglutathione hydrolase FrmB, FGH.
What is the protein family that this protein belongs to?
Belongs to the esterase D family.
Protein: FLIK_ECOLI
Sequence: MIRLAPLITADVDTTTLPGGKASDAAQDFLALLSEALAGETTTDKAAPQLLVATDKPTTKGEPLISDIVSDAQQANLLIPVDETPPVINDEQSTSTPLTTAQTMALAAVADKNTTKDEKADDLNEDVTASLSALFAMLPGFDNTPKVTDAPSTVLPTEKPTLFTKLTSEQLTTAQPDDAPGTPAQPLTPLVAEAQSKAEVISTPSPVTAAASPLITPHQTQPLPTVAAPVLSAPLGSHEWQQSLSQHISLFTRQGQQSAELRLHPQDLGEVQISLKVDDNQAQIQMVSPHQHVRAALEAALPVLRTQLAESGIQLGQSNISGESFSGQQQAASQQQQSQRTANHEPLAGEDDDTLPVPVSLQGRVTGNSGVDIFA
What is the function of this protein?
Controls the length of the flagellar hook.
What are the official names of this protein?
Flagellar hook-length control protein.
What is the protein family that this protein belongs to?
Belongs to the FliK family.
Protein: DEAD_ECO57
Sequence: MAEFETTFADLGLKAPILEALNDLGYEKPSPIQAECIPHLLNGRDVLGMAQTGSGKTAAFSLPLLQNLDPELKAPQILVLAPTRELAVQVAEAMTDFSKHMRGVNVVALYGGQRYDVQLRALRQGPQIVVGTPGRLLDHLKRGTLDLSKLSGLVLDEADEMLRMGFIEDVETIMAQIPEGHQTALFSATMPEAIRRITRRFMKEPQEVRIQSSVTTRPDISQSYWTVWGMRKNEALVRFLEAEDFDAAIIFVRTKNATLEVAEALERNGYNSAALNGDMNQALREQTLERLKDGRLDILIATDVAARGLDVERISLVVNYDIPMDSESYVHRIGRTGRAGRAGRALLFVENRERRLLRNIERTMKLTIPEVELPNAELLGKRRLEKFAAKVQQQLESSDLDQYRALLSKIQPTAEGEELDLETLAAALLKMAQGERTLIVPPDAPMRPKREFRDRDDRGPRDRNDRGPRGDREDRPRRERRDVGDMQLYRIEVGRDDGVEVRHIVGAIANEGDISSRYIGNIKLFASHSTIELPKGMPGEVLQHFTRTRILNKPMNMQLLGDAQPHTGGERRGGGRGFSGERREGGRNFSGERREGGRGDGRRFSGERREGRAPRRDDSTGRRRFGGDA
What is the function of this protein?
DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.
What are the official names of this protein?
ATP-dependent RNA helicase DeaD, Cold-shock DEAD box protein A.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURD_SYNE7
Sequence: MQHAHVIGLGKSGCAAALLLRQQGWQVELSDRNAVAAPPELVSQGVQFRLGESLDPVAWGWQTPEQRPNCIVVSPGVPWDLPGLRQAAEELQIETLGELELAWRTLSDIPWVAVTGTNGKTTTTALIAAIFERAGLQAPACGNIGFAACEVARQQQQGEAKPLDWVIAEASSYQIEAAATLAATIGLWTTFTPDHLNRHYTLENYFTIKASLLDRAQQQVLNGDDPYLRNQANATSRWPLAFWTSTQGAEALPTSRDRGFWIEEGWVIDRGDRLFPVERFSMVGNHNQQNLLMAVAAARLAGIEAEAIAEAMANFPGIAHRLERVATWQGIELINDSKATNYDAAWVGLQAVPGPTILIAGGEAKQGDDQAWLDLIQAKARAVLLIGSAAPLFARRLAEVGYSSPVENAETLDRAVPRAVELAQSLDASHVLLSPACASFDQYPNFEARGDHFRRCAQAIAKG
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_SHESW
Sequence: MRLNTLSPAAGSKHAPKRVGRGMGSGLGKTAGRGHKGQKSRSGGGVRPGFEGGQMPLKIRLPKFGFTSRRAMVTAEVRVLELAKVNGDVIDLNALKDANVITRNIQFAKIVLSGTIERPVTVKGLKVTKGARAAIEAAGGKIEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: MAMKL_MAGSA
Sequence: MIVNDNQNILYVGIDFGYSKTVIMTSRGKSLSLKSLVGYPKDFVGLARLGRPYLVGDEAFEMRSYLHLRNPLLDGLLNPISEQDIDVTRHFISHIIKCAEPAAGEKVFAVIGVTPRFTAANKKLLLKLAQEYCQNVLLMSAPFLAGNSIGKASGSIIIDIGAWTTDICAMKGRIPRPEDQSSIAKAGSYIDERLKNSILERYPALQINANIARMVKEQFAFVGRPQLVAACEFRSAGKAVRCDVTEQVRAACESPFAEIAERIGAVLCVVPPEDQALVLKNIVITGAGAQIRGLPEYVKSMLAPYGDARVSIANEPLMEACKGALSMAQEIPPHFWGQL
What is the function of this protein?
Protein with ATPase activity which forms pole-to-pole filaments in vivo, probably with MamK.  Efficient filament formation requires MamK.  Probably promotes turnover of MamK filaments, by providing a monomer pool (PubMed:24957623).  In vivo, in the absence of its paralog MamK, forms thin filaments from pole to pole (PubMed:20161777).  In vitro forms straight filaments and bundles in the absence of ATP.  Filament formation is triggered by KCl and MgCl(2); polymerizes more slowly and makes thinner filaments than MamK (PubMed:20161777).  Expression in E. coli yields a filament in the cell's longitudinal axis; the protein nucleates at one pole or the cell septum (PubMed:20161777).
What are the official names of this protein?
MamK-like protein, Magnetosome cytoskeleton protein MamK-like.
What is the protein family that this protein belongs to?
Belongs to the FtsA/MreB family. MamK subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Note=Protein forms filaments extending along most of the cell associated with its inner curvature, in the correct position to be filaments that are seen associated with magnetosomes (PubMed:20161777). Colocalizes in filaments with paralog MamK (PubMed:24957623).
Protein: CDMI_TALVE
Sequence: MQNLGASMDNNKKFKVVIVGGSIAGLTLAHCLSKFGIDYVVLEKRREIAPQEGASVGIMPNGGRVLEQLGLFDDVERAIEPLSVAQLVYPDGFCSESEYPKKLCERFGFPLAFLDRQMLLESLYANLPDITRVKTNSAVIAVEHEDDRVRVLTTDNCSYEGHLVVGADGIHSTIRKEMWRAASSLHQGQVEDTNSMMNITYACVYGISSAHPLLKPGQQITCFNDGWSILSVVGKNGRTFWFLFLKLEREYKYNEAPKYTKEDAIANCDRLSAHTFWDTVTFGDVWSRREVFTMTPLEEGVFEQWSCGRIVCIGDSMHKFAPNIGQGANCAIEDAGELANALARIFNDREKGDGFKPSTPDLSNMLEQFQGKRISRIKALYKVARLAIRLQARDGLAMTLMGRYVMPYLGDKVADWASRDIADGAILEFLPPPERSGSGWQKYSQKSKKSNTPFILAVLAGLGFLLTMFKQQWEYHQDS
What is the function of this protein?
FAD-dependent monooxygenase; part of the gene cluster that mediates the biosynthesis of chrodrimanin B, a meroterpenoid that acts as a potent blocker of insect GABA-gated chloride channels (PubMed:30417647).  The first step of the pathway is the biosynthesis of 6-hydroxymellein by the polyketide synthase cdmE (PubMed:30417647).  The prenyltransferase cdmH acts as a 6-hydroxymellein 5-farnesyltransferase and produces the hydrophobic metabolite verruculide C (PubMed:30417647).  The FAD-dependent monooxygenase cdmI further converts verruculide C into verruculide B (PubMed:30417647).  The terpene cyclase cdmG then produced the pentacyclic molecule 3-hydroxypentacecilide A, the backbone structure of chrodrimanin B, via folding the farnesyl moiety of the substrate into the chair-boat conformation (PubMed:30417647).  The short-chain dehydrogenase/reductase cdmF functions as the 3-OH dehydrogenase that oxidizes the C-3 hydroxyl group of 3-hydroxypentacecilide A and produces chrodrimanin C, the dehydrogenated product of 3-hydroxypentacecilide A (PubMed:30417647).  The cytochrome P450 monooxygenase cdmJ then accepts both 3-hydroxypentacecilide A and chrodrimanin C and functions as a C-7-beta-hydroxylase to produce respectively chrodrimanin H and chrodrimanin F (PubMed:30417647).  The dioxygenase cdmA accepts chrodrimanin H to afford chrodrimanin E, which is further transformed to chrodrimanin A by the dioxygenase cdmD (PubMed:30417647).  CdmA can also accept chrodrimanin C as substrate to convert it into verruculide A, which is further converted into chrodrimanin T by cdmD (PubMed:30417647).  The last step of the biosynthesis is proposed to be performed by the acetyltransferase cdmC which acetylates chrodrimanin A to yield chrodrimanin B (Probable).  The pathway may also lead to the production of additional shunt products, including chrodrimanins T and U (PubMed:30417647).
What are the official names of this protein?
FAD-dependent monooxygenase cdmI, chrodrimanin B biosynthesis cluster protein I.
What is the protein family that this protein belongs to?
Belongs to the paxM FAD-dependent monooxygenase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL14_PECAS
Sequence: MIQEQTMLNVADNSGARRVMCIKVLGGSHRRYAGVGDIIKITIKEAIPRGKVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVILNNNSEQPIGTRIFGPVTRELRNEKFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: FIS_PROHU
Sequence: MFEQRVNSDVLTVATVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQPLLDMVMQYTRGNQTRAAQMMGINRGTLRKKLKKYGMN
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.
Protein: RS21_LACPL
Sequence: MAKTVVRKNESLDDALRRFKRTVSKSGTLQEYRKREFYEKPSVKKKLKSEAARKRKNRRRFK
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: DPS_ENTCL
Sequence: MSTAKLVKSKATNLLYTRNDVSDSDKKATIELLNRQVIQFIDLSLITKQAHWNMRGANFIAVHEMLDGFRTALVTHLDTMAERAVQLGGVALGTTQVINSKTPLKSYPLDIHTVQDHLKELADRYAIVANDVRKAIGEAKDEDTADIFTAASRDLDKFLWFIESNIE
What is the function of this protein?
During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages.  It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction.  One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.
What are the official names of this protein?
DNA protection during starvation protein.
What is the protein family that this protein belongs to?
Belongs to the Dps family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS1_ENT38
Sequence: MLDNTRLRIAIQKSGRLSDDSRELLARCGIKINLHTQRLIALAENMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLTRRAQGEDPRYFTLRRLDFGGCRLSLAMAVDEAWDGPAALNGKRIATSYPHLLKRYLDQKGVQFKSCLLNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMPEAKQQLIDRLLTRIQGVIQARESKYIMMHAPTERLDEVIALLPGAERPTILPLAGDQQRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH_COXB1
Sequence: MAKQEQNIVYLYCDGACRGNPGPGGWGVLLRYNQHERQLHGGVANTTNNQMELTAAIEGLKSLKKPCQVVVTTDSQYLRRGITEWLPVWKRRGWRTSNKKPVKNQPLWETLEREVERHTIVWHWVKGHSGHAENEIADELANRGIDEVLKRGAR
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POGK_MOUSE
Sequence: MESRAYPLNLTLKEEQKEEEVEIQELEDGPIDMQKVQICSEGAWVPALFDEVAIYFSDEEWEVLTEQQKALYREVMRMNYETVLSLEFPFPKPDMINRLERDEECPNSDEWRLQGVTFAENEESDFRTPDWASPTNATSHFPQPQPFNSFGLRLPQDITELPEWTEGYPFYMAMGFPGYDLSADDLASKFQFSRGMRRSYDAGFKLMVVEYAESTNNCQAAKQFGVLEKNVRDWRKVKPQLQNAHAMRRAFRGPKNGRFALVDQRVAEYVRYMQAKGDPITREAMQLKALEIAQEMNIPEKGFKASLGWCRRMMRRYDLSLRHKVPVPQHLAEDLTEKLVTYQQSVLALRRTHDYEVAQMGNADETPICLEVPSRVTVDNQGEKPILVKTPGREKLRITAMLGVLADGRKLPPYIILRGTYIPPGKFPSGMEIRCHRYGWMTEDLMQDWLEVVWRRRTGAVPRQRGMLILNGFRCHATDSVKSSMENMNTDMVIIPGGLTSQLQVLDVVVYKPLNDSVRAQYSNWLLAGNLALSPTGNAKKPPLGLFLEWIMVAWNSISSESIVQGFRKCHISSNLEDEGDVLWEIEGELPKEPPKECGPESVAEGD
What are the official names of this protein?
Pogo transposable element with KRAB domain.
What are the subcellular locations of this protein?
Nucleus.
Protein: RBFA_PSEA6
Sequence: MAREFSRTDRVGQQIHKEIASILQNEFKNRDPRLGMVTVSAVEVSRDLAYTKIYVTFFENDEEVMDNYLSILEENKGYIRTLLANRMRMRAVPAIKFVRDGSLSEGIRISNLVDETLNKDKERARNAGRSLDEDEQED
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAII_RHIET
Sequence: MLRILTKDMLETDRRAFDEMFRARAAVFRDRLGWQVDVRDQWERDRYDEAEDPVYLVTQQPSGTLTGSLRLLPTTGATMLKSEFRHFFDQPIDVDSPTTWECTRFCLHPHAGDMKQSRAVATELLSGLCDLALDTGIENIVGVYDVAMVAVYRRIGWRPTPLARSRPEIGKLYVGLWDVTADNCRTLRANLSRLLEQASPYPARVLVDGGMR
What is the function of this protein?
Required for the synthesis of autoinducer molecules which bind to RaiR and that are involved in the restriction of nodule number.
What are the official names of this protein?
Acyl-homoserine-lactone synthase, Autoinducer synthesis protein RaiI.
What is the protein family that this protein belongs to?
Belongs to the autoinducer synthase family.
Protein: TSN33_MOUSE
Sequence: MARRPGVPAAYGDEFSFVSPLVKYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAALACLAVDPAILLIVVGVLMFLLTFCGCIGSLRENICLLQTFSLCLTIVFLLQLAAGILGFVFSDKARGKVSEIINNAIVHYRDDLDLQNLIDFGQKKFSCCGGISYRDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPNQAVINTMCGQGMQALDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILLSQVLVNQIKDQIKLQLYNQQHRADPWY
What is the function of this protein?
Plays an important role in normal erythropoiesis (PubMed:17158226).  It has a role in the differentiation of erythroid progenitors (PubMed:17158226).  Regulates maturation and trafficking of the transmembrane metalloprotease ADAM10 (PubMed:23035126, PubMed:30463011).  Negatively regulates ligand-induced Notch activity probably by regulating ADAM10 activity (By similarity).  Mediates docking of ADAM10 to zonula adherens by interacting with ADAM10 and, in a PDZD11-dependent manner, with the zonula adherens protein PLEKHA7 (PubMed:30463011).
What are the official names of this protein?
Tetraspanin-33, Tspan-33, Penumbra, mPen, Proerythroblast new membrane.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, adherens junction. Cytoplasm. Note=Is localized to zonula adherens by PLEKHA7 by a PDZD11-dependent interaction.
Protein: ARLY_METBF
Sequence: MSNILRRGRLEAAQDEEILRYTSSMEADRWIFDADIAVDLAHTVMLKEQGIINREDCSKILSGLLKIREEGMEKLDFSYEDIHISLESRLIDMVGEDVGGRMHSGRSRNDEVATCIRLVLREELTGLLEEIHELRQALLTLAEKHTETLMPGFTHMQHAQPTTLAHHLCAHEAALGRDFDRIQDAYSRVNLCPLGAAAFASTGFNLNRKRTQELLGFDGLLENSMDAVSTRDFLIECASGFTNLMINLSRMAEELVIWSSSEFNFIELDDMYASTSSIMPQKKNPDTAELMRGKTGVAVGALMSLITICKGLPLSYNRDLQEATPNLWRSVETVRASVRIMEGMIKTMKVRPEVLVAQSVTGFTTATELADTFVRETGIPFRTAHQIVGMLAREMEKPTLKKIDSVAEIVLGESLSSRGLKEKMVKEALNPFSNVEIRKIAGGPAPEEMRNYLSKRQTELELNRQEIATLKDITDSAFENLLATVNEYRQA
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.