PharMolix/UniProtQA huggingface dataset:
Protein: RBP5_BPT5
Sequence: MSFFAGKLNNKSILSLRRGSGGDTNQHINPDSQTIFHSDMSHVIITETHSTGLRLDQGAGDYYWSEMPSRVTQLHNNDPNRVVLTEIEFSDGSRHMLSGMSMGVGAKAYGIINPQIMSQGGLKTQITASADLSLDVGYFNTGTSGTIPQKLRDGTGCQHMFGAFSGRRGFASSAMYLGGAALYKSAWSGSGYVVADAGTLTIPSDYVRHPGARNFGFNAIYVRGRSCNRVLYGMEGPNYTTGGAVQGASSSGALNFTYNPSNPESPKYSVGFARADPTNYAYWESMGDPNDSANGPIGIYSEHLGIYPSKITWYVTNLVYNGSGYNIDGGLFNGNDIKLSPREFIIKGVNVNNTSWKFINFIEKNFNVGNRADFRDVGCNLSKDSPSTGISGIATFGLPTTESNNAPSIKGGNVGGLHANVVSIYNFLPSASWYVSSNPPKIGNNYGDVWSENLLPLRLLGGSGSTILSGNIVFQGNGSVHVGTVGLDLNSSRNGAIVCTMEFIDDTWLSAGGIGCFNPTEMLSQGAEYGDSRFRIGGNTINKKLHQILSLPAGEYVPFFTIKGTVVNACKLQAAAYNPTPYWVSGLPGSVGQTGYYTLTYYMRNDGNNNISIWLDSSMSNIIGMKACLPNIKLIIQRLT
What is the function of this protein?
Structural component of the distal part of the tail.  Mediates T5 binding to its host receptor, the E. coli outer membrane ferrichrome transporter fhuA protein.  Upon binding to host FhuA, pb5 undergoes conformational changes that are probably the key to the transmission of the signal through the tail to the capsid, triggering DNA release.
What are the official names of this protein?
Receptor-binding protein pb5, RBP-pb5, Tail protein pb5.
What are the subcellular locations of this protein?
Virion. Note=Localizes at the tip of the central tail fiber.
Protein: GLMU_STAEQ
Sequence: MQRHAIILAAGKGTRMKSKKYKVLHEVAGKPMVEHVLNNVKQAGVDQIVTIIGHGAESVKDTLGNQSLYSFQDKQLGTAHAVKMAHEHLADKEGTTLVVCGDTPLITYQTLQSLIEHHESTQSHVTVLSASTINPYGYGRIIRNHNGILERIVEEKDANDSERAIKEISSGIFAFNNRVLFEKLEQVKNDNAQGEYYLPDVLSLILKDGGKAEVYCTEDFDEIIGVNDRLMLSEAEKALQQRINRYHMENGVTIIDPSSTFIGTDVKIGIDTTIEPGVRIGGHTTIEEDVWIGQYSEINNSTIHSNANIKQSVINDSIVGENTTVGPFAQLRPGSNLGSEVKVGNFVEVKKADIKDGAKVSHLSYIGDAEIGERTNIGCGSITVNYDGANKFKTIVGKDAFIGCNTNLIAPVTVGNHTLIAAGSTITDNIPEDSLALARARQVNKEGYLKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURC_CLONN
Sequence: MSFNFLKDNNKKVHFIGIGGISMSGLAEILLNSGYRVSGSDRSESDLTKHLQAKGAEIYIGHNGNNLKDVDLVVYTAAIPDSNPELVKARECNIQTMDRAEFLGHVMQGHKYNIAISGTHGKTTTTSMFSHISLSANLDPTILVGGNLDVINGNVRVGNSEYFVTEACEYKASFLKFYPYIGVILNIEADHLDFYKDINDIQNTFLKFAKLIPNDGFLIVNADDKRCVEVSKQVDCNVITFGINNGDVRAKNIVFNNGRPTFDVYRNEEKLFTLTLNVPGNHNILDALASISSALSLNVPVDSIIEGLSTFNGAHRRFEIKGKVDGITVVDDYAHHPTEIKAALNAAKNFPHKRVFCVFQPHTYSRTISLFDDFANSFSNADTLVLADIYAAREKDTGVVSSTMLGDKIRENGVNCKNLHSFEDIVTFLKGELKDGDLLITIGAGDVYRVGEMFLEAK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATC_CHLTB
Sequence: MTESYVNKEEIISLAKNAALELEDAHVEEFVTSMNDVIALMQEVIAIDISDIILEATVHHFVGPEDLREDMVTSDFTQEEFLSNVPVSLGGLVKVPTVIK
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: MURE2_CLOAB
Sequence: MKLKQLLQNIDYDLIKGDININIEGISYNSKKVKQNYVFVSIKGARFDGHDFIKEAAQNGAAAVIIDEDFHDSIENTTLVKVKNSKVALACLCNLFYEEPSRELNLVGVTGTNGKTTVIHYIRDMLEAFGNSTGTIGTLGYELKDKEINVEKINPTTPEALELNQILRDFIDKGAKNAVMEVTSSALMKHRVDYCSFKVGVFTNLSQDHLDEHGTIENYKNEKIKLFKMCPVGVINLDDNIAGEIIEKGTCEFFTYGVLTNADLTASDMVYKPNSVSFNVHYKGISSKVKVNVPGEFTVYNVLAAIGSLLCLGIDFESILKLVSSIKPVLGRLETINNPLNKNIIIDYAHTPDSLEKLLIMAREMTNGRIITVFGCGGDRDKSKRGLMGMAVGILSDYCIITSDNPRHEKPEDIIRDIERGMQTINSSYEKITDRRCAIKRGIEILKEEDILIIAGKGHEDYQIIGDNKVHFDDREVVNELLG
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase 2, Meso-A2pm-adding enzyme 2, Meso-diaminopimelate-adding enzyme 2, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase 2, UDP-MurNAc-tripeptide synthetase 2, UDP-N-acetylmuramyl-tripeptide synthetase 2.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPG_XANCP
Sequence: MYDAVTRPSPPADASAWPRRITQAVKVGNVIVGGGHPVVVQSMTNTDTADIAGSVKQVAELWRAGSEMVRLTVNNAESAAAIPRIVEKLRMMGIEVPLIGDFHYNGHQLLTAEPACAEALAKYRINPGNVGFGKKKDLQFAQLIEFAIQYDKPVRIGANWGSLDQALAAQLMDENSKRETPWDAGRVLREALIRSAVDSAERAVELGLPRERIILSAKVSGVQELIAVYRDMAARCDFALHLGLTEAGIGSKGIVASAAALSVLLQEGIGDTIRISLTPEPGQSRTQEVIVAQELLQTTGQRAFTPLVTACPGCGRTTSEFFQELAGVVQNHVRAKMPEWKISNPGAENMTLAVMGCVVNGPGESRHANIGISLPGTGEAPSAPVFVDGEKTVTLRGENIAYEFIDLIDQYVERTYVRRAG
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: RT34_MOUSE
Sequence: MARKKVRPRLIAELARRVRALREQRNQPRDSQLYALDYETLTRPHSGRRLPVRAWADVRRESRLLQLLARLPLFGLGRLVTRKSWLWQHDEPCYWRLTRVRPDYTAQNLDHGRAWGILTFKGKSEDTAREIEQVMYHDWRLVPKHEEEAFTAFTAKPEDRLNSVPYPPLLRAMILAERQKNGDTSVQEPLLNLERTRMRPWDYPAKQETKGRAKGTPV
What is the function of this protein?
Required for mitochondrial translation, plays a role in maintaining the stability of the small ribosomal subunit and the 12S rRNA that are required for mitoribosome formation.
What are the official names of this protein?
28S ribosomal protein S34, mitochondrial, MRP-S34, S34mt, T-complex expressed gene 2 protein.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mS34 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: FLP09_CAEEL
Sequence: MNQFYALFLVACIAAMANAYEEPDLDALAEFCGKESNRKYCDQIAQLATQHAIGINQEQVRMEKRKPSFVRFGKRSGYPLVIDDEEMRMDKRKPSFVRFGRK
What is the function of this protein?
KPSFVRF-amide: Has no effect on somatic body wall muscle, inhibits contraction of vaginal vera muscle, and inhibits the activity of the dissected pharyngeal myogenic muscle system (PubMed:9920762, PubMed:16187307).  Acts as a ligand for the npr-22 receptor in vitro (PubMed:16377032).
What are the official names of this protein?
FMRFamide-like neuropeptides 9.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: GSHB_PROMP
Sequence: MKFLFVVDPIKNINPLKDSSAALMQASSKKKIEVWICTPQDLEARGDEVWASSWRAEVCPWVSFKENKCIPLAEFNCIWMRKDPPVNEGYLYATHLLEVAERKGVKVINKPSSLRAWNEKLGALRYSHLMAPTIVASKVKDLINFAQINHDVVVKPLGGKGGQGVIRLTKDSPGIKAMIELITSQEQLPVMMQKFIPEVKEGDKRIIIVNGEPIGSINRIPQGGDFRSNLAMGGKAEKTNLTAKEKKICTELSQHFKDEGLFFVGIDVINEMLSEINVTSPTGLREIETLSNKSVSDKVIEKLLEII
What are the official names of this protein?
Glutathione synthetase, GSH synthetase, GSH-S, GSHase, Glutathione synthase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic GSH synthase family.
Protein: METRN_RAT
Sequence: MLVAALLCALCCGLLAASARAGYSEDRCSWRGSGLTQEPGSVGQLTLDCTEGAIEWLYPAGALRLTLGGSDPGTRPSIVCLRPTRPFAGAQVFAERMAGNLELLLAEGQGLAGGRCMRWGPRERRALFLQATPHRDISRRVAAFQFELHEDQRAEMSPQAQGFGVDGACRPCSDAELLLTACTSDFVIHGTIHGVVHDMELQESVITVVATRVIRQTLPLFQEGSSEGRGQASVRTLLRCGVRPGPGSFLFMGWSRFGEAWLGCAPRFQEFSRVYSAALAAHLNPCEVALD
What is the function of this protein?
Involved in both glial cell differentiation and axonal network formation during neurogenesis.  Promotes astrocyte differentiation and transforms cerebellar astrocytes into radial glia.  Also induces axonal extension in small and intermediate neurons of sensory ganglia by activating nearby satellite glia (By similarity).
What are the official names of this protein?
Meteorin, Hypoxia/reoxygenation regulatory factor.
What is the protein family that this protein belongs to?
Belongs to the meteorin family.
What are the subcellular locations of this protein?
Secreted.
Protein: NIKD_ECOLI
Sequence: MPQQIELRNIALQAAQPLVHGVSLTLQRGRVLALVGGSGSGKSLTCAATLGILPAGVRQTAGEILADGKPVSPCALRGIKIATIMQNPRSAFNPLHTMHTHARETCLALGKPADDATLTAAIEAVGLENAARVLKLYPFEMSGGMLQRMMIAMAVLCESPFIIADEPTTDLDVVAQARILDLLESIMQKQAPGMLLVTHDMGVVARLADDVAVMSDGKIVEQGDVETLFNAPKHTVTRSLVSAHLALYGMELAS
What is the function of this protein?
Part of the ABC transporter complex NikABCDE involved in nickel import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Nickel import ATP-binding protein NikD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CSLC3_ORYSJ
Sequence: MAPPPNTYSESWWGGKEERGTPVVVKMDNPYSLVEIDGPGMAAPSEKARGKNAKQLTWVLLLRAHRAVGCVAWLAAGFWAVLGAVNRRVRRSRDADAEPDAEASGRGRAMLRFLRGFLLLSLAMLAFETVAHLKGWHFPRSAAGLPEKYLRRLPEHLQHLPEHLRRHLPEHLRMPEKEEIEGWLHRAYVAWLAFRIDYIAWAIQKLSGFCIALFMVQSVDRLVLCLGCFWIKLRGIKPVADTSISNDDIEATAGDGGGYFPMVLIQMPMCNEKEVYETSISHVCQIDWPRERMLVQVLDDSDDETCQMLIKAEVTKWSQRGVNIIYRHRLNRTGYKAGNLKSAMSCDYVRDYEFVAIFDADFQPNPDFLKLTVPHFKGNPELGLVQARWSFVNKDENLLTRLQNINLCFHFEVEQQVNGVYLSFFGFNGTAGVWRIKALEDSGGWMERTTVEDMDIAVRAHLNGWKFIFLNDVKVLCELPESYQAYRKQQHRWHSGPMQLFRLCLPAVFKSKISTWKKANLVMLFFLLRKLILPFYSFTLFCVILPLTMFVPEAELPIWVICYVPVIMSVLNILPAPKSFPFVIPYLLFENTMSVTKFNAMVSGLFQLGSSYEWVVTKKAGRTSSESDILALAEAADADARPPPAKLHRGVSEGGLKEWAKLHKEQEDATAAAAAAAAPGTPVKKSKAAKAPNRIFKKELALAFLLLTAATRSLLSAQGLHFYFLLFQGVTFLAVGLDLIGEQVS
What is the function of this protein?
Probable beta-1,4-glucan synthase rather involved in the synthesis of the xyloglucan backbone than cellulose.  Seems to work simultaneously with xyloglucan 6-xylosyltransferase.  Xyloglucan is a noncellulosic polysaccharides of plant cell wall and consists of a glucan backbone substituted by xylose, galactose and fucose (By similarity).
What are the official names of this protein?
Probable xyloglucan glycosyltransferase 3, Cellulose synthase-like protein C3, OsCslC3.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. Plant cellulose synthase-like C subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: UBIG_COXBN
Sequence: MTPSEQNIDKEELAKFSDLAQDWWNPAGKMKPLHLINPVRLKYIEQQITLKGKHVLDVGCGGGLLSEALAKHGAIVTGVDMSESLIDVAKNHAEQQQLNINYQCQDIEILTKDAQRFDIITCMELLEHVPDPQRMIKNCAALIKPGGKLFFSTINRNFKAYLYTIVGAEYVFNLLPKGTHDYAQFIHPSELTQWAESGGLRLLDITGIHYHPLKNEFDLSRDVSVNYLACFTHE
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: ULAG_ECODH
Sequence: MSKVKSITRESWILSTFPEWGSWLNEEIEQEQVAPGTFAMWWLGCTGIWLKSEGGTNVCVDFWCGTGKQSHGNPLMKQGHQMQRMAGVKKLQPNLRTTPFVLDPFAIRQIDAVLATHDHNDHIDVNVAAAVMQNCADDVPFIGPKTCVDLWIGWGVPKERCIVVKPGDVVKVKDIEIHALDAFDRTALITLPADQKAAGVLPDGMDDRAVNYLFKTPGGSLYHSGDSHYSNYYAKHGNEHQIDVALGSYGENPRGITDKMTSADMLRMGEALNAKVVIPFHHDIWSNFQADPQEIRVLWEMKKDRLKYGFKPFIWQVGGKFTWPLDKDNFEYHYPRGFDDCFTIEPDLPFKSFL
What is the function of this protein?
Probably catalyzes the hydrolysis of L-ascorbate-6-P into 3-keto-L-gulonate-6-P.  Is essential for L-ascorbate utilization under anaerobic conditions.
What are the official names of this protein?
Probable L-ascorbate-6-phosphate lactonase UlaG, L-ascorbate utilization protein G.
What is the protein family that this protein belongs to?
Belongs to the UlaG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EMIL1_HUMAN
Sequence: MAPRTLWSCYLCCLLTAAAGAASYPPRGFSLYTGSSGALSPGGPQAQIAPRPASRHRNWCAYVVTRTVSCVLEDGVETYVKYQPCAWGQPQCPQSIMYRRFLRPRYRVAYKTVTDMEWRCCQGYGGDDCAESPAPALGPASSTPRPLARPARPNLSGSSAGSPLSGLGGEGPGESEKVQQLEEQVQSLTKELQGLRGVLQGLSGRLAEDVQRAVETAFNGRQQPADAAARPGVHETLNEIQHQLQLLDTRVSTHDQELGHLNNHHGGSSSSGGSRAPAPASAPPGPSEELLRQLEQRLQESCSVCLAGLDGFRRQQQEDRERLRAMEKLLASVEERQRHLAGLAVGRRPPQECCSPELGRRLAELERRLDVVAGSVTVLSGRRGTELGGAAGQGGHPPGYTSLASRLSRLEDRFNSTLGPSEEQEESWPGAPGGLSHWLPAARGRLEQLGGLLANVSGELGGRLDLLEEQVAGAMQACGQLCSGAPGEQDSQVSEILSALERRVLDSEGQLRLVGSGLHTVEAAGEARQATLEGLQEVVGRLQDRVDAQDETAAEFTLRLNLTAARLGQLEGLLQAHGDEGCGACGGVQEELGRLRDGVERCSCPLLPPRGPGAGPGVGGPSRGPLDGFSVFGGSSGSALQALQGELSEVILSFSSLNDSLNELQTTVEGQGADLADLGATKDRIISEINRLQQEATEHATESEERFRGLEEGQAQAGQCPSLEGRLGRLEGVCERLDTVAGGLQGLREGLSRHVAGLWAGLRETNTTSQMQAALLEKLVGGQAGLGRRLGALNSSLQLLEDRLHQLSLKDLTGPAGEAGPPGPPGLQGPPGPAGPPGSPGKDGQEGPIGPPGPQGEQGVEGAPAAPVPQVAFSAALSLPRSEPGTVPFDRVLLNDGGYYDPETGVFTAPLAGRYLLSAVLTGHRHEKVEAVLSRSNQGVARVDSGGYEPEGLENKPVAESQPSPGTLGVFSLILPLQAGDTVCVDLVMGQLAHSEEPLTIFSGALLYGDPELEHA
What is the function of this protein?
May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly.  Has cell adhesive capacity.
What are the official names of this protein?
EMILIN-1, Elastin microfibril interface-located protein 1, Elastin microfibril interfacer 1.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Note=Found mainly at the interface between amorphous elastin and microfibrils.
Protein: FLIE_LISIN
Sequence: MAIESINAASVLPKVTLGETAKTDNATGAGNTFTQMLDSMSDTQSNAQTSVSNLLTTGEGNASDVLIQMKKAESEMKTAAVIRDNVIESYKQLLNMQV
What are the official names of this protein?
Flagellar hook-basal body complex protein FliE.
What is the protein family that this protein belongs to?
Belongs to the FliE family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: ENO_STRA1
Sequence: MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYGGLGTQKAVDNVNNVIAEAIIGYDVRDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVARAAADYLEVPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPIAFQEFMIMPVGAPTFKEALRWGAEVFHALKKILKERGLETAVGDEGGFAPKFEGTEDGVETILKAIEAAGYEAGENGIMIGFDCASSEFYDAERKVYDYSKFEGEGGAVRTAAEQIDYLEELVNKYPIITIEDGMDENDWDGWKALTERLGGRVQLVGDDFFVTNTDYLARGIKEEAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNLKK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: FDHD_SHISS
Sequence: MKKTQRKEIENVTNITGVRQIELWRRDDLQHPRLDEVAEEVPVALVYNGISHVVMMASPKDLEYFALGFSLSEGIIESPRDIFGMDVVPSCNGLEVQIELSSRRFMGLKERRRALAGRTGCGVCGVEQLNDIGKPVQPLPFTQTFDLNKLDDALRHLNDFQPVGQLTGCTHAAAWMLPSGELVGGHEDVGRHVALDKLLGRRSQEGESWQQGAVLVSSRASYEMVQKSAMCGVEILFAVSAATTLAVEVAERCNLTLVGFCKPGRATVYTHPQRLSN
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity.  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
What are the official names of this protein?
Sulfur carrier protein FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCCA_HALMT
Sequence: MFSKVLVANRGEIAVRVMRACEELGVRTVAVYSEADKHGGHVRYADEAYNIGPARAADSYLDHESVIEAARKADADAIHPGYGFLAENAEFARKVEDSEFTWVGPSADAMERLGEKTKARSLMQDADVPVVPGTTEPADSAEDVKAVADDYGYPVAIKAEGGGGGRGLKVVHSEDEVDGQFETAKREGEAYFDNASVYVEKYLEAPRHIEVQILADEHGNVRHLGERDCSLQRRHQKVIEEAPSPALSEDLRERIGEAARRGVRAAEYTNAGTVEFLVEDGEFYFMEVNTRIQVEHTVTEEVTGLDVVKWQLRVAAGEELDFSQDDVEIEGHSMEFRINAEAPEKEFAPATGTLSTYDPPGGIGIRMDDAVRQGDEIGGDYDSMIAKLIVTGSDREEVLVRAERALNEFDIEGLRTVIPFHRLMLTDEAFREGSHTTKYLDEVLDPERIEAAVERWSPEAVAGDEEEGEVTERTFTVEVNGKRFEVSLEERGAPAIPLGGASAAASASKPSGPRKRREESDEGGQQVIEGDGESVAAEMQGTILAVEVDEGDDVEPGDTVCILEAMKMENDVVAERGGTVSQVLVGEGDSVDMGDVLLVLE
What is the function of this protein?
This is one of the subunits of the biotin-dependent propionyl-CoA carboxylase (PCC), the enzyme catalyzing the carboxylation of propionyl-CoA/propanoyl-CoA to D-methylmalonyl-CoA/(S)-methylmalonyl-CoA.  Within the holoenzyme, the alpha subunit catalyzes the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain, while the beta subunit then transfers the carboxyl group from carboxylated biotin to propionyl-CoA (By similarity).  Propionyl-CoA carboxylase is involved in propionate utilization and in the production of the poly(3-hydroxybutyrate-co-3-hydroxyvalerate)(PHBV), which is a water-insoluble biopolymer used as intracellular energy reserve material when cells grow under conditions of nutrient limitation (PubMed:25398867).  Propionyl-CoA carboxylase is also able to catalyze the carboxylation of acetyl-CoA (PubMed:25398867).
What are the official names of this protein?
Propionyl-CoA carboxylase, biotin carboxylase and biotin-carboxyl carrier subunit, PCC.
Protein: AROE_NEIPO
Sequence: MTALPRYAVFGNPVAHSKSPQIHQQFTLQEGVDIEYGRICADIDGFAQAVSTFFETGGCGANVTVPFKQEAFALADEHSDRALAAGAVNTLILLKNGKLRGDNTDGIGLVNDITQVKNIAIEGKTILLLGAGGAVRGVIPVLKEHRPARIVIANRTHAKAEELARLFGIEAVPMADLNGGFDIIINGTSGGLSGQLPAVNPEIFRSCRLAYDMVYGDAAQTFLNFAQSNGAAEVSDGLGMLVGQAAASYHIWRGFTPDIRPVIEYMKAL
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: MT1_SCYSE
Sequence: PGPCCNDKCVCKEGGCKEGCQCTSCRCSPCEKCSSGCKCANKEECSKTCSKACSCCPT
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.  Class I MTS in marine crustacea are involved in the sequestration of elevated levels of heavy-metal ions.
What are the official names of this protein?
Metallothionein-1, MT-1, Metallothionein-I, MT-I.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 3 family.
Protein: CC160_XENTR
Sequence: MEDNKHWIEKLFPPHFTVQDFFSQSFEPEQLISEKISKEKVKNVEKMYHNAAERCLEAGKWKRKEELSNIFSYDPNIPDDQKEKEPPVGNLHDNVTCPIAAHVDDQCIWRENELKVLRHEMQQRYSEGAKFKNQLDACKLELSELKAKDKNTEQELGKAKEALTLSKTHIRNKGILVKQLQKDKLQKDSEIQSLKKDLHEKSVMINSLNKNLCIAGEEIQELKLKSKDLEQELITVKQQQGVKEGTLIENLKRNYILEKNKLLREIENLKEEERKREKTHSLNLAALDLLRKHFSSQSINTSTEVIQLKIVH
What are the official names of this protein?
Coiled-coil domain-containing protein 160 homolog.
What is the protein family that this protein belongs to?
Belongs to the CCDC160 family.
Protein: PAP1_CWPXB
Sequence: MNRNPDQNTLPNITLKIIETYLGRIPSVNEYHMLKLQARNIQKITVFNKDIFVSLVKKNKKRFFSDVDTSASEIKDRILSYFSKQTQTYNIGKLFTIIELQSVLVTTYTDILGVLTIKAPNVISSKISYNVTSMEELARDMLNSMNVAVIDKAKVMGRHNVSSLVKNVNKLMEEYLRRHNKSCICYGSYSLYLINPNIRYGDIDILQTNSRTFLIDLAFLIKFITGNNIILSKIPYLRNYMVIKDENDNHIIDSFNIRQDTMNVVPKIFIDNIYIVDPTFQLLNMIKMFSQIDRLEDLSKDPEKFNARMATMLEYVRYTHGIVFDGTRNNMPMKCIIDENNRIVTVTTKDYFSFKKCLVYLDENVLSSDILDLNADTSCDFESVTNSVYLIHDNIMYTYFSNTILLSDKGKVHEISARGLCAHILLYQMLTSGEYKQCLSDLLNSMMNRDKIPIYSHTERDKKPGRHGFINIEKDIIVF
What is the function of this protein?
Polymerase that creates the 3'-poly(A) tail of mRNA's.
What are the official names of this protein?
Poly(A) polymerase catalytic subunit, Poly(A) polymerase large subunit, PAP-L.
What is the protein family that this protein belongs to?
Belongs to the poxviridae poly(A) polymerase catalytic subunit family.
Protein: ASPH2_XENTR
Sequence: MVWALPRTSSPSCIAPSYKPDSGWIKMSAEWLIDWSCLLNGLRDLIAGCIQAVRDCNSFALTTVICLLMLFAWYCYRVGKDQPRSPFATVNLLIQSSEAKGLQNGFAYCHSRECVRCTHNDGLNQKLYHNLQEYAKRYSWSGMGRIHKGIREQGRYLNNRPSIQKPEVFFLPDLPTMPYFPRDAQKHDVELLEQNFATILSEFEAIYKAFSNCSLPQGWKVNSTPSGEWFTFYLVNQGVTIPSNCKKCPRTYRLLGNLRTFIGNNVFGNACISVLTPGTVITEHYGPTNIRIRCHLGLRIPGNCELVVGGEPQCWAEGHCLLFDDSFLHTAFHEGSAEEGPRVIFMVDLWHPNVAAAERQALDSIFAPGR
What is the function of this protein?
May function as 2-oxoglutarate-dependent dioxygenase.
What are the official names of this protein?
Aspartate beta-hydroxylase domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the aspartyl/asparaginyl beta-hydroxylase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: Y4041_METAC
Sequence: MTIGIVSYGAYVPRYRIKIEEIARLWGDDAEALKNGLMVYEKSVPDVDEDAATIAVEAARYAMARSGVDPSRIGAVYTGSESHPYAVKPTSTIVAQAIGATPEMTAADFEFACKAGTAAVQACMGLVGSGMIDLGLAIGADVSQGAPSDALEYTAAAGGVACLIGRKESELAAIIEDTYSFTTDTPDFWRREGMPYPEHGGRFTGEPGYFKHVTNGAKGLLEKLGTKPEDYDYAVFHQPNGKFPSKAAKILGFTKAQITPGLVVPKIGNTYSGSCLMGIAATLDQAKPGDRIFATAFGSGAGSDAFSITVTDRIEEIRNRAPKVSELIKDPVYIDYARYARHKGKIRLA
What are the official names of this protein?
UPF0219 protein MA_4041.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. UPF0219 family.
Protein: DPH3_KLULA
Sequence: MSTYDEVEIEDMTFDPDTQIFTYPCPCGDRFQISIDDMYDGEDIAVCPSCSLMIQVVFDKEDLVEYYVEANLEPPGKIAVAV
What is the function of this protein?
Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2.  DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising KTI11/DPH3 and a NADH-dependent reductase, predominantly CBR1.  Acts as an electron donor to reduce the Fe-S cluster in DPH1-DPH2 keeping the [4Fe-4S] clusters in the active and reduced state.  Restores iron to DPH1-DPH2 iron-sulfur clusters which have degraded from [4Fe-4S] to [3Fe-4S] by donating an iron atom to reform [4Fe-4S] clusters, in a manner dependent on the presence of elongation factor 2 and SAM.  Associates with the elongator complex and is required for tRNA Wobble base modifications mediated by the elongator complex.  The elongator complex is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s 2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine).
What are the official names of this protein?
Diphthamide biosynthesis protein 3.
What is the protein family that this protein belongs to?
Belongs to the DPH3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.