PharMolix/UniProtQA huggingface dataset:
Protein: END3_TREPA
Sequence: MRLLDSKGVHAVFEQLHAANPQPQGELHWRNTFTLLVAVLLSAQATDKSVNKATAALFDVADTPQAMLALGEERLCSYIRTINLYPTKARRIIALSAELIERFAAQVPCDAHALESLPGVGHKTANVVLNMGFGIPTIAVDTHILRTAPRIGLSSGRTPRAVERDLLVVTPREFRMHAHHWILLHGRYTCTARRPRCTECCLRDLCCKNNI
What is the function of this protein?
DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity.  The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site.  The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
What are the official names of this protein?
Endonuclease III, DNA-(apurinic or apyrimidinic site) lyase.
What is the protein family that this protein belongs to?
Belongs to the Nth/MutY family.
Protein: Y620_MYCPN
Sequence: MLKQISTTTKKEPWVNLSLLMVHNSFLDINYFWTTNLSIHKYGNYLVNNLNKAQWNTLSSVLQLKKAPHSGFLWTDQHNYIPLHRVKTNLCEKIELAAVQQSHPFHQTIHDFLRQSTCPKKRQRLIEKLQIPNELRWFLGFNALKKLSQFVVFELDNTNKLTSETLSQFFTTKFVNKVYFNQIQFEYNNFVGLLEDHERDLVEFSTHFFNSFFEQPDHLTKSFFEQYYALTRQRERLLHNLKVQSYETKHGVNTYFENLQITRAQQQANQLKRAFKKQQRNSVQLINRFMSSLWWSQTKIKFKSIFNFYKTRILEKRIVAKRIQIKIWLLKELKQMRLLNPDLLVSTIAESERLVEQLMSNIQRLYQQILQLKPGQSLNWKYQAISFELEKLTKPIVLTHDAVIGFLIKSRLAFLQEYAKGLNRCEQHNKLVNELKQNVLLNQNQYKGEVSQSYSVVNQKAVFKGFIQTVKAALNYTKLKHTLDPFNLMNIVQERCFEQLLTTYEKLDWTKYELNQLYFVCRALWTNLHKQTQHFFTKYQFITHGVVDFVFNQGRNQTQFASLKANLNRDWNSPKWKLLVNKTVNKYFEANLHHPQAYLLLPNRNATTLTEANTTTINQLNLKTQLKQWRAHYHLLLQDIRLIQWLYKKEIKQKQQQIKALLKNYGTLNKLLNTQISKVNNVVRKTFFVDSEECDLNRLQASNKLHFNLLNAMVNVISFCLKKCRQNPKKLNRTANLKMLLDNTFKNGIPSWMIFSDLNKINTKQRFKLYLLFKLLLHPQLVLVDSFVNFNKHTYNFTRGLLIAHQNQQGIAYLFNDPHNNLVKDFFTQTINFETRAKN
What are the official names of this protein?
Uncharacterized protein MG422 homolog.
Protein: PG46_MYCTO
Sequence: MSFVIAVPEALTMAASDLANIGSTINAANAAAALPTTGVVAAAADEVSAALAALFGSYAQSYHAFGAQLSAFHAQFVQSLTNGARSYVVAEATSAAPLQDLLGVVNAPAQALLGRPLIGNGANGADGTGAPGGPGGLLLGNGGNGGSGAPGQPGGAGGDAGLIGNGGTGGKGGDGLVGSGAAGGVGGRGGWLLGNGGTGGAGGAAGATLVGGTGGVGGATGLIGSGGFGGAGGAAAGVGTTGGVGGSGGVGGVFGNGGFGGAGGLGAAGGVGGTASYFGTGGGGGVGGDGAPGGDGGAGPLLIGNGGVGGLGGAGAAGGNGGAGGMLLGDGGAGGQGGPAVAGVLGGMPGAGGNGGNANWFGSGGAGGQGGTGLAGTNGVNPGSIANPNTGANGTDNSGNGNQTGGNGGPGPAGGVGEAGGVGGQGGLGESLDGNDGTGGKGGAGGTAGTDGGAGGAGGAGGIGETDGSAGGVATGGEGGDGATGGVDGGVGGAGGKGGQGHNTGVGDAFGGDGGIGGDGNGALGAAGGNGGTGGAGGNGGRGGMLIGNGGAGGAGGTGGTGGGGAAGFAGGVGGAGGEGLTDGAGTAEGGTGGLGGLGGVGGTGGMGGSGGVGGNGGAAGSLIGLGGGGGAGGVGGTGGIGGIGGAGGNGGAGGAGTTTGGGATIGGGGGTGGVGGAGGTGGTGGAGGTTGGSGGAGGLIGWAGAAGGTGAGGTGGQGGLGGQGGNGGNGGTGATGGQGGDFALGGNGGAGGAGGSPGGSSGIQGNMGPPGTQGADG
What are the official names of this protein?
Uncharacterized PE-PGRS family protein PE_PGRS46.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PE family. PGRS subfamily.
Protein: TRMD_RHORT
Sequence: MSLRAVVLTLFPEMFPGPLGHSIAGKALETGAWSIEAVDIRSFATDRHHTVDDSPFGGGAGMVMRPDVVDAAIAASWPGDGPLVYLTPRGRVLDQALVRELAQAPSLTLLCGRYEGVDQRVLDERGMLEISIGDYVLSGGEAAAQVLLDAVVRLLPGVVGKTESLEDESFERGLLEYPHYTRPAEWRGRTVPEVLTSGHHQKVSDWRQARSEEITQTRRPDLWARYVAARTSLDRGCGQ
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU_BORBZ
Sequence: MAKEVFQRTKPHMNVGTIGHVDHGKTTLTAAISIYCSKLNKDAKALKYEDIDNAPEEKARGITINARHIEYETANRHYAHVDCPGHADYIKNMITGAAQMDAAILLVAADSGAEPQTKEHLLLAQRMGIKKIIVFLNKLDLADPELVELVEVEVLELVEKYGFSADTPIIKGSAFGAMSNPEDPESTKCVKELLESMDNYFDLPERDIDKPFLLAVEDVFSISGRGTVATGRIERGIIKVGQEVEIVGIKETRKTTVTGVEMFQKILEQGQAGDNVGLLLRGVDKKDIERGQVLSAPGTITPHKKFKASIYCLTKEEGGRHKPFFPGYRPQFFFRTTDVTGVVALEGKEMVMPGDNVDIIVELISSIAMDKNVEFAVREGGRTVASGRILEILE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2084_PAEAT
Sequence: MDEATAKSGTEQDGLTPVKPPEAELLVVTGMSGAGRSTASDALEDHGWYVVDNLPPQMLGTLAEIVSHAPKSIPKLAVVVDVRSKDLFTDIQTALGALSASGITFRVLFLDANDDVLVRRFEQGRRPHPLQGGGRILDGIGIEREVLRELREHADVVLDTSEFNVHGLATAITELFSDTGPVTLRLNVMSFGFKYGLPVDANFVADARFIPNPHWVPQLRPHTGLDEDVSDYVLGAEGVQEFVDRYVRALEPVLDGYRQENKHYATLAVGCTGGKHRSVAVAMELSKRLAQYPRVTVTTTHRDLGRE
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein AAur_2084.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: KHSE_PARL1
Sequence: MAVYTEVPDEELEAFLATYDIGTLMSYKGIAEGVENSNFMLHTDAGTYFLTLYEKRVAESELPFFLGLMNHLVDRGISCPTPIRNRKGEMLGRLAERPAAIVSFLEGISVRRPQPRHCVELGRALAQLHMAGADFKLARKNALNVDGWGPLFDSCRDGIDAYQPGLAQELDKELAVLTREWPRDLPHGVIHADLFPDNVFFIGDRLSGLIDFYFACNDAFAYDLAICLNAWCFEADGSFNITKARALLQAYTQVRPLEPAEIHALPLLARGSAMRFLLTRLYDLINHPPGAFVKPKDPKEYLTRLRFHRGVASPAGYGLDA
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the pseudomonas-type ThrB family.
Protein: RL9_BACAN
Sequence: MKVIFLKDVKGKGKKGEVKNVPDGYANNFLLKQGLAAEATNSSMKTLEAQKRKEEKDAAAELESAKQLKETLEKLTVELKAKSGEGGRLFGSITSKQIVDAMQKSHKIKLDKRKFEMDDAIRALGYTNVTVKLHPQVTATVKVHVSEQ
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: FMT_THEFY
Sequence: MRLVFAGTPEVAVPSLDALLASEHEVVAVVTRPDAAAGRGRRLVASPVARRAAEAGIEVLKPARADDPAFLDRLRELAPDCCPVVAYGALLRQEALDIPRYGWVNLHFSLLPAWRGAAPVQHAILHGDDITGATTFQIERELDAGPVYGTVTEPIGPRDTSGDLLERLAKSGAELLVRTIDGIAKNELVPRPQGSEGVSYAPKLTPDDARVDFTAPALRVDRLIRACTPAPGAWTRFRGTRIKLGPVEPLPDAAPLPPGQLVATSRDVLVGTATHPVRLGEVQPQGKKAMPAADWARGARIGDGERFGDD
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: LRIQ3_MOUSE
Sequence: MFHGTITKELTSHEEWSHYNENIIEDQKDFVFVKYSGLHLKSMENLQTCISLRVCIFSNNFLTDIQPLQSCKKLIKLDLHGNQIKTLPDKNFWSGLKNLKLLYLHDNGFSKLKNICVLSGCVSLIGLTMFDCPVSLKKGYRHVLVNSIWPLKALDHHVISDEEIIQNWRLPERFKTFSPSLFFNLYPALIKGTTYEDEIKNIKHIISRINEILAHNSPVLIIQRWIRGFIVRKHLSPYFKHKKHYHGKMIRVLETKLICIGRSDEDKYLEDFFFIKPECNIKGKVAHWKQMRYSPADFKYSTEYGKHISCLSYELKTKYIDGKSKQPRHHIHKGQKAMKAESEDEEVDTEFRISAMKIPLYSSRSLKYGAMLKEMKWDYFPQYLQPFPATRQKPPVKRETLWKLKKRREFLATQRAGMKLHMFDDVDKYYSEQKQHEEEARKFAAMVTAQVTQERASVNIREKLNKKIYMTRKLMEKDNETIQKGLQQIWRERLAYLEKVRERKFMFLAEKKLNAADQSLVISLNNERSILLKGITQVERLKKHMSEKKAKHLDVIEKWEEQKYKQDLLMEMKKLRVEEIQKRHCEEKFVIDTLILQKGYERLEEAKAKVEYIKTFYTSKSHKRRNEAMPDHI
What are the official names of this protein?
Leucine-rich repeat and IQ domain-containing protein 3, Leucine-rich repeat-containing protein 44.
Protein: EDE1_YEAST
Sequence: MASITFRTPLSSQEQAFYNQKFHQLDTEDLGVVTGEAVRPLFASSGLPGQLLSQVWATVDIDNKGFLNLNEFSAALRMIAQLQNAPNQPISAALYESTPTQLASFSINQNPAPMQSGSATGNTNNTDIPALSSNDIAKFSQLFDRTAKGAQTVAGDKAKDIFLKARLPNQTLGEIWALCDRDASGVLDKSEFIMAMYLIQLCMSHHPSMNTPPAVLPTQLWDSIRLEPVVVNQPNRTTPLSANSTGVSSLTRHSTISRLSTGAFSNAASDWSLSFEKKQQFDAIFDSLDKQHAGSLSSAVLVPFFLSSRLNQETLATIWDLADIHNNAEFTKLEFAIAMFLIQKKNAGVELPDVIPNELLQSPALGLYPPNPLPQQQSAPQIAIPSRASKPSLQDMPHQVSAPAVNTQPTVPQVLPQNSNNGSLNDLLALNPSFSSPSPTKAQTVVQNNTNNSFSYDNNNGQATLQQQQPQQPPPLTHSSSGLKKFTPTSNFGQSIIKEEPEEQEQLRESSDTFSAQPPPVPKHASSPVKRTASTTLPQVPNFSVFSMPAGAATSAATGAAVGAAVGAAALGASAFSRSSNNAFKNQDLFADGEASAQLSNATTEMANLSNQVNSLSKQASITNDKKSRATQELKRVTEMKNSIQIKLNNLRSTHDQNVKQTEQLEAQVLQVNKENETLAQQLAVSEANYHAAESKLNELTTDLQESQTKNAELKEQITNLNSMTASLQSQLNEKQQQVKQERSMVDVNSKQLELNQVTVANLQKEIDGLGEKISVYLTKQKELNDYQKTVEEQHAQLQAKYQDLSNKDTDLTDREKQLEERNRQIEEQENLYHQHVSKLQEMFDDLSQRKASFEKADQELKERNIEYANNVRELSERQMNLAMGQLPEDAKDIIAKSASNTDTTTKEATSRGNVHEDTVSKFVETTVENSNLNVNRVKDDEEKTERTESDVFDRDVPTLGSQSDSENANTNNGTQSGNETANPNLTETLSDRFDGDLNEYGIPRSQSLTSSVANNAPQSVRDDVELPETLEERDTINNTANRDNTGNLSHIPGEWEATPATASTDVLSNETTEVIEDGSTTKRANSNEDGESVSSIQESPKISAQPKAKTINEEFPPIQELHIDESDSSSSDDDEFEDTREIPSATVKTLQTPYNAQPTSSLEIHTEQVIKYPAPGTSPSHNEGNSKKASTNSILPVKDEFDDEFAGLEQAAVEEDNGADSESEFENVANAGSMEQFETIDHKDLDDELQMNAFTGTLTSSSNPTIPKPQVQQQSTSDPAQVSNDEWDEIFAGFGNSKAEPTKVATPSIPQQPIPLKNDPIVDASLSKGPIVNRGVATTPKSLAVEELSGMGFTEEEAHNALEKCNWDLEAATNFLLDSA
What is the function of this protein?
Functions at the internalization step of the clathrin-mediated endocytosis (CME) as an early-acting scaffold protein.  Requires clathrin adapter proteins, ENT1/2 and YAP1801/2, for normal spatiotemporal dynamics and viability.  Binds to biological membranes in a ubiquitin-dependent manner.
What are the official names of this protein?
EH domain-containing and endocytosis protein 1, Bud site selection protein 15.
What is the protein family that this protein belongs to?
Belongs to the VDP/USO1/EDE1 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localized to actin cortical patches concentrated in the developing bud tip in cells with small buds and at the mother-daughter neck in cells undergoing cytokinesis. Localization can be maintained in the absence of polymerized actin filaments.
Protein: RS20_PROM9
Sequence: MANNKSAKKRIKIAERNRLINKSYKSTVRTLTKKTLENCEKYKKDPNDENKDLVKTSLNKAFSLIDKAVKKNVLHKNNGANRKSKINNLVKTTLATQ
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: MUTS_BORBZ
Sequence: MEKNVTPMIRQYLDIKKKYKDAVLFFRVGSFYEMFFDDAIEVSKLLNLTLTKRENVPMCGVPYHTSKEYIRKLILFDKKVAICEQASNSTSGGPLEREVVEVITPGVIIDEDFLNDDINNYLVAISDYKDYYSFSYIDLSTSSLGIMFYENGFFEKLKRDLEKYSPKEIIVSENFYYEYSEKLNLSRFLINRVPTWHLDKDIAIKTIKEHFNILGLSSLGFDEEKPYYISIFLIINHIKNNLKNLLSNIDKIDINNDSSYMFLDDVTQVNLELVKNNNDFSSQYSLYSVLNDCKTAMGKRLLREFILNPILNISEINTRLDHVEFFCKNISLTVTLRETFINIWDIERIISRIQMKRYIKKDFLFIEKALSVFFTVKKLFDKHNFDYWNFDKFEEDSISKVYFLINSAISSAPDELIKRGYDLKLDNLKDLKINANKYIDQYLESERLLSKINNLKIRKTNNRGLFFEVTKSNYAQVPPHFMESQALNSSKRYKTEKLISLEVDINNAEDNVVAFEQEIFDEIASNVVMHNKVLKKVAEFFAYIDLVVNFGYLAKKNEYKRPVLTSGKEILLEKSRHPVVEHYTKNTEIFTENFVRINKEKYFCLITGPNMAGKSTYLRQVALITLMAHIGSFVPASKALIGITDKIFCRIGASDNIAKGESTFLVEMNETANILRNATEKSLIIMDEVGRGTSTNDGLAIAYSIIEYILEYIKARSLFATHFHELSSINHQAFINLSMKIEKQGNDLVFLREVEEKPSLNSYGIYVARIAGLPLRVIDRANVILESLVGREGNSCLEFLPHVSSDGNDKEILKNDTDIHIKLNEYLELKNFISNIDINNITPFQSIELLNQIVLKVISQSS
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: CLPS_YERPB
Sequence: MGKNNDWLNFEHLVKDKQIEALQPPSMYKVILNNDDYTPMEFVIDVLQKFFSYDIERATQLMLNVHYQGKAICGVFTAEVAETKVAHVNQYARENEHPLLCTLEKA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: IF4G_SCHPO
Sequence: MSSKPPSNTPKFSYARALASSQSNKSNSTKASENNTATAEKQAVKPSGVEPTNTSRANAQKKTESTGKITSEADTEKYNSSKSPVNKEGSVEKKSSEKSSTNNKPWRGDNTSKPSANSSAERTSSQHQKPETSSQIGKDNAAPVENVNEKSTSQETAPPVSTVPIQFGSITRNAAIPSKPKVSGNMQNKSGVSSYSSKSQSVNSSVTSNPPHTEEPVAAKPEASSTATKGPRPTTSASNTNTSPANGAPTNKPSTDINTTDPATQTTQVSASNSPALSGSSTPSNTSSRSNRQNHGNFSEKRHYDRYGNSHPSYNKYSHYQHGFNYNNSGNNRNESGHPRFRNSRRNYNNQGAYPTYMSNGRSANQSPRNNPQNVNNGSTPIQIPVSLQTPYGQVYGQPQYIVDPNMVQYGPILQPGYVPQYYPVYHQTPYTQNFPNMSRSGSQVSDQVVESPNSSTLSPRNGFAPIVKQQKKSSALKIVNPVTHTEVVVPQKNASSPNPSETNSRAETPTAAPPQISEEEASQRKDAIKLAIQQRIQEKAEAEAKRKAEEKARLEAEENAKREAEEQAKREAEEKAKREAEEKAKREAEEKAKREAEENAKREAEEKAKREAEEKAKREAEEKAKREAEEKAKREAEEKAKREAEEKAKREAEEKAKREAEENAKREAEEKAKREAEENAKREAEEKVKRETEENAKRKAEEEGKREADKNPEIKSSAPLASSEANVDTSKQTNATEPEVVDKTKVEKLKASEGKSTSSLSSPSHSTSSKRDLLSGLESLSLKTNPKSEQCLESLLNSQFITDFSALVYPSTIKPPSTEEALKAGKYEYDVPFLLQFQSVYTDKPMKGWDERMKETVASAFSDKSSRGMYSSSRQSSRSGSNTHSHAGPGFGGPSERKGISRLGIDRGFSSSGAGFGSGSNYKSAPSRGVSHHGHGGMSGSHRGSQRGSRRGGGERDKPDPSSLTIPVDQVAPLQLSANRWQPKKLTEKPAETKGEDEEALLPPEVVQRKVKGSLNKMTLEKFDKISDQILEIAMQSRKENDGRTLKQVIQLTFEKATDEPNFSNMYARFARKMMDSIDDSIRDEGVLDKNNQPVRGGLLFRKYLLSRCQEDFERGWKANLPSGKAGEAEIMSDEYYVAAAIKRRGLGLVRFIGELFKLSMLSEKIMHECIKRLLGNVTDPEEEEIESLCRLLMTVGVNIDATEKGHAAMDVYVLRMETITKIPNLPSRIKFMLMDVMDSRKNGWAVKNEVEKGPKTIAEIHEEAERKKALAESQRPSSGRMHGRDMNRGDSRMGGRGSNPPFSSSDWSNNKDGYARLGQGIRGLKSGTQGSHGPTSLSSMLKGGSVSRTPSRQNSALRREQSVRAPPSNVAVTSANSFELLEEHDHDNDGGQKDSNSKTSS
What is the function of this protein?
Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome.
What are the official names of this protein?
Eukaryotic translation initiation factor 4 gamma, eIF-4-gamma, eIF-4G.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic initiation factor 4G family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Note=Localized to the perinuclear region, the growing tips and septum.
Protein: MNMA_LACLS
Sequence: MSGKSPAQTRVVVGMSGGVDSSVTALLLKEQGYDVIGVFMKNWDDTDENGVCTATEDYKDVAAVADQIGVPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVMCNKEIKFKAFLDYAMELGADYVATGHYAQVRTDEDGTVHMLRGADNNKDQTYFLSQLTQEQLKKTMFPLGHLEKPEVRRIAEKAGLATAKKKDSTGICFIGEKNFKKFLGEYLPAQPGKMMTLDGVEMGNHAGLMYYTIGQRGGLGIGGQHGQLTSDPWFVVGKDLTTNTLYVGQGFHHEHLYSTSLDASDLSFTREMPETFDLHCTAKFRYRQEDTGVTIHVKADKVTVDFDEPVRAITPGQAVVFYDGEECLGGAMIDVAYKEQKVMQYQ
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HDFR_SHIB3
Sequence: MDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLENQLGVNLFTRHRNNIRLTAAGEKLLPYAEMLMSTWQAARKEVAHTSRHNEFSIGASASLWECMLNQWLGRLYQNQDAHTGLQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEFSSQLLGYFTLALYTSAPSKLKGDLNYLRLEWGPDFQQHEAGLIGADEVPILTTSSAELAQQQIAMLNGCTWLPVSWARKKGGLHTVVDSTTLSRPLYAIWLQNSDKNALIRDLLKINVLDEVY
What is the function of this protein?
Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.
What are the official names of this protein?
HTH-type transcriptional regulator HdfR, H-NS-dependent flhDC regulator.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: GARA_MYCTU
Sequence: MTDMNPDIEKDQTSDEVTVETTSVFRADFLSELDAPAQAGTESAVSGVEGLPPGSALLVVKRGPNAGSRFLLDQAITSAGRHPDSDIFLDDVTVSRRHAEFRLENNEFNVVDVGSLNGTYVNREPVDSAVLANGDEVQIGKFRLVFLTGPKQGEDDGSTGGP
What is the function of this protein?
Involved in regulation of glutamate metabolism.  Acts as a phosphorylation-dependent molecular switch that modulates the activities of Kgd, Gdh and GltB.
What are the official names of this protein?
Glycogen accumulation regulator GarA.
Protein: MTLD_YERP3
Sequence: MKALHFGAGNIGRGFIGKLLADAGAQLTFADVNQPLLDALNKRKSYQVNVVGEQARVEEVKNVSAVNSGSPEVVALIAEADIVTTAVGPQILARIAATVAQGLITRHQQGNTRPLNIIACENMVRGTSQLKQHVFAALSEDEQIWVEQHVGFVDSAVDRIVPPSEAGSTDILAVTVETFSEWIVDGTQFKGQPPEIVGMELTDNLMAFVERKLFTLNTGHAITAYLGQLAGHQTIRDAILDPAVRQTVKGAMEESGAVLIKRYAFDPQKHAAYINKILSRFENPYLHDDVERVGRQPLRKLSAGDRLIKPLLGTLEYQLPHDSLVTGIAAAMSYRSEQDPQAQELVTLLAQLGPKAALAQISGLPADSEVVEQAVSVYNAMQQKLAH
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: Y411_ENCCU
Sequence: MDSANGCGILKKERRSEEHHYKVHRRVLRWMKSAEKIKRELDEGYEKKWRNRSIEEIKEQKKVHDIVEVMKLLRDKEECDRFFVRTGKYMKGGSERWKMVANGILEEGGEKKVRKVEVGLFKGERGGSVVYHLMFRPTETERTGRVGGSSFGKYDDVDEIKKEESSDMSGFRYPPGVRCEMTSNGNEFRIEYRNPKNTSEVLRTLTILRIPEI
What are the official names of this protein?
UPF0329 protein ECU04_0110.
What is the protein family that this protein belongs to?
Belongs to the UPF0329 family.
Protein: TTCA_MARN8
Sequence: MPEAMTASPEKTPASDYERRQKLELNKLQKRLRREVGQAIADFSMIEAGDKVMCCLSGGKDSYAMLDILLNLQKSAPVRFELIAVNLDQKQPGFPEHVLPDYLESMGIEYHIIEKDTYSIVKEKVPEGKTTCGLCSRLRRGILYNFAEEHGVTKIALGHHRDDLLETLFLNMFYGGKLKSMPPVLHSDDGRNTVIRPLAYAREKDIARYASLREFPIIPCNLCGSQENLQRQVIKEMFQTWDKQHPGRLETMFRALCNVEPSHLADPELYDFREGRRLGGKRQAVQTAEPQQDFGRLDVLNL
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_STRCO
Sequence: MKPEEIERMRDEALAAFAAADSLDALQEAKVAHTGGASPLALANREIGALPPQAKAEAGKRVGMARGAVNKALAARQEELEAERDARVLVEEAVDVTLPHDRVPAGARHPLTTLSERIEDIFVAMGYEVAEGPEAEAEWFNFDALNIGPDHPARGEADTFFVQGPEGGAESGVVLRTHTSPVQIRSALTRELPVYVICPGRVYRTDELDATHTPVFHQVELLAVDEGLTMADLKGTLDHMVQSLFGAEMKTRLRPNFFPFTEPSAEMDMLCYVCKGASVGNPDRPCRTCSSEGWIELGGCGMVNPRVLTACGIDPEKYSGFAFGFGIERMLMFRHNVEDMRDMVEGDVRFTRPFGMEI
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPCKG_METBU
Sequence: MPDSLRPLLRKPFGVLYTGIGSDAVKSLVKDLNNPTKLISVGDVTTFHLLDSNIIPDILIVDDRTKRAPASSQVVFGTKHKGFAEITVDNPPGVITEDLINVISDAIVSDKNVRIFVQGEEDLAALPAILMAPLNSVVLYGQPDEGVMLVRVTESLKAELKDLFDKILEKQDHKEQLLHNVRRKLNGY
What is the function of this protein?
Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
What are the official names of this protein?
GTP-dependent dephospho-CoA kinase, Dephospho-coenzyme A kinase, DPCK.
What is the protein family that this protein belongs to?
Belongs to the GTP-dependent DPCK family.
Protein: FGFP3_HUMAN
Sequence: MTPPKLRASLSPSLLLLLSGCLLAAARREKGAASNVAEPVPGPTGGSSGRFLSPEQHACSWQLLLPAPEAAAGSELALRCQSPDGARHQCAYRGHPERCAAYAARRAHFWKQVLGGLRKKRRPCHDPAPLQARLCAGKKGHGAELRLVPRASPPARPTVAGFAGESKPRARNRGRTRERASGPAAGTPPPQSAPPKENPSERKTNEGKRKAALVPNEERPMGTGPDPDGLDGNAELTETYCAEKWHSLCNFFVNFWNG
What is the function of this protein?
Heparin-binding protein which binds to FGF2, prevents binding of FGF2 to heparin and probably inhibits immobilization of FGF2 on extracellular matrix glycosaminoglycans, allowing its release and subsequent activation of FGFR signaling which leads to increased vascular permeability.
What are the official names of this protein?
Fibroblast growth factor-binding protein 3, FGF-BP3, FGF-binding protein 3, FGFBP-3.
What is the protein family that this protein belongs to?
Belongs to the fibroblast growth factor-binding protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS21_NITSB
Sequence: MPGILVRPDQSFEEAYRLFKKQVDRNLIVTEARARRFYEKPTERRKKEKIAARKKMLKRLYMLRRYESRL
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: EXG_YARLI
Sequence: MKLTKLVALAGAALASPIQLVPREGSFLGFNYGSEKVHGVNLGGWFVLEPFITPSLFEAFGNNDANVPVDEYHYTAWLGKEEAEKRLTDHWNTWITEYDIKAIAENYKLNLVRIPIGYWAFSLLPNDPYVQGQEAYLDRALGWCRKYGVKAWVDVHGVPGSQNGFDNSGLRDHWDWPNADNVQHSINVINYIAGKYGAPEYNDIVVGIELVNEPLGPAIGMEVIEKYFQEGFWTVRHAGSDTAVVIHDAFQEKNYFNNFMTTEQGFWNVVLDHHQYQVFSPGELARNIDQHIAEVCNVGRQASTEYHWRIFGEWSAALTDCTHWLNGVGKGPRLDGSFPGSYYQRSCQGRGDIQTWSEQDKQESRRYVEAQLDAWEHGGDGWIYWTYKTENALEWDFRRLVDNGIFPFPYWDRQFPNQCGF
What are the official names of this protein?
Glucan 1,3-beta-glucosidase, Exo-1,3-beta-glucanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
What are the subcellular locations of this protein?
Secreted.
Protein: HEM0_BOVIN
Sequence: MVTAAMLLQRCPVLIRSPTGLLGKMIKTHQFLFGIGRCPILATQGPSFSQIHLKATKAGGDSPSWAKSHCPFMLLELQDGKSKIVQKAAPEVQEDVKTFKTDLPTSLASTSLKKTFSSPQEPEKNSEKVTHLIQNNMAGDHVFGYDQFFRDKIMEKKQDHTYRVFKTVNRWADAYPFAEHFFEASVASKDVSVWCSNDYLGMSRHPRVLQATQEILQRHGAGAGGTRNISGTSKFHVELEQELAELHQKDSALLFSSCFVANDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPDHLKKLLKKSNPETPKIVAFETVHSMDGAICPLEELCDVAHQYGALTFVDEVHAVGLYGSRGAGIGERDGIMHKIDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFTTSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHMRQLLMDRGLPVIPCPSHIIPIRVGDAMLNTRICDLLLSKYGIYVQAINYPTVPRGEELLRLAPSPHHSPQMMEDFVEKLLEAWTEVGLPLQDISIAACNFCRRPVHFELMSEWERSYFGNMGPQYVTTYA
What is the function of this protein?
Catalyzes the pyridoxal 5'-phosphate (PLP)-dependent condensation of succinyl-CoA and glycine to form aminolevulinic acid (ALA), with CoA and CO2 as by-products (By similarity).  Contributes significantly to heme formation during erythropoiesis (By similarity).
What are the official names of this protein?
5-aminolevulinate synthase, erythroid-specific, mitochondrial, ALAS-E, 5-aminolevulinic acid synthase 2, Delta-ALA synthase 2, Delta-aminolevulinate synthase 2.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein. Note=Localizes to the matrix side of the mitochondrion inner membrane.
Protein: KINH_BOTFU
Sequence: MSNSIKVVCRFRPQNRIENEQGAQPVVKFEADDTCALDSNGAAGSFTFDRVFGMSSRQKDIFDFSIKPTVDDILNGYNGTVFAYGQTGAGKSYTMMGTNLDNDDGRGVIPRIVEQIFASILSSPGTIEYTVRVSYMEIYMERIRDLLQPQNDNLPIHEEKNRGVYVKGLLEVYVSSVQEVYEVLKRGGDARVVASTNMNAESSRSHSIFVITITQKNVETGSAKSGQLFLVDLAGSEKVGKTGASGQTLEEAKKINKSLSALGMVINNLTDGKSSHIPYRDSKLTRILQESLGGNSRTTLIINCSPSSYNAEETLSTLRFGMRAKAIKNKAKVNAELSPAELKALLRKAQSQVTTFETYVSTLEGEVQLWRKGESVPKEQWAPPLAGVSGAKAAAAQTPRPSTPSRLATESRAETPVAERSATPGIPIDKDEREEFLRRENELQDQITEKETQIAAAEKTLRDTKEELTYLKERDTKVNKDNEKLTSEANEFKMQLERLAFESKEAQITMDSLKEANAELTAELDELKQQLLNVKMSAKESTAALDEKEKRKAEKMAQMMAGFDLGGDVFSENEATIKKVIDHIDSLHEQSSAGEAIPPDEFEELKAKLVETQGIVRQAELSMFGSSSNDANVKRREELEQRLQVLEQEYEDLLERNLGEGDVAEIKERLEKAYSNNQDIKVELVEDLKKEVAQKSAEIEKFKAVNEDLQQRVKSGSASNGTAPGSASGKTVQQQIAEFDVMKKSLMRDLQNRCERVVELEISLDETREQYNNVLRSSNNRAQQKKMAFLERNLEQLTHVQRQLVEQNGSLKKEVAIAERKLIARNERIQSLESLLQDSQEKLTTASHRYGFPLYFRIDFNHTSIALLTFPLDSKPNCQQ
What is the function of this protein?
Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport.  Its motor activity is directed toward the microtubule's plus end.
What are the official names of this protein?
Kinesin heavy chain.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Kinesin subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: Y996_STRR6
Sequence: MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASVFEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEMESILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILHYAIKHMATSLVLVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFSYREKTDLI
What are the official names of this protein?
UPF0758 protein spr0996.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.