PharMolix/UniProtQA huggingface dataset:
Protein: ANKX_LEGPH
Sequence: MVKIMPNLPGLYFLQAYPSEEIWRLFVDGRFWSKENGWRGYESREPGCLNAALESLCSIALQVEKSGEEFELSVDLIKRIHKKCGKKVEELQEKNPGELRTDEPVSFGIPAGRASIKGIEEFLSLVFLTEGGAEFGPGKAGPFGPRFDKNYFKNLNPEQIPDLAKQIYFDMCKYGHSNTNHFYLAVMKNVDVYLEKITQSYNKEIKTAETLDEKLKIIVKHIRMYEVLHPFRDANGRTFVNNLLNILLMQQGLPPATFYEPNVFDLYSAEELVVVVKEAIFNTVEIIEQSKRKTPITLYGYHSSLEEQTKFRDMLDSPSYEKIKHMDFSDLNPEKLHLKTQKCLSSLNEQYPLHRGAIYLSDPGEIKLLLSNRNESQINQQIEQGAPPIYVGKTPAHLAVISGNMAMLDELIAKKADLSLQDYDGKTALHYAAECGNMQIMGKILKVVLSQEDAIKVLNIKDNHGKTAFHYAAEFGTPELISALTTTEVIQINEPDNSGSSAITLAYKNHKLKIFDELLNSGADISDELLDAIWARKDKETLGKIIAKNEKILLNKEAFRIAISLGSVSLVKKFLRAGVDIDIPLTKDKATPLMLSINSGNPKLVSYLLKKGANTRLTDTSGNSVLHYVFYSKAENREALANIITEKDKKLINQPNANGNPPLYNAVVVNDLKMATILLEMGARVDFEDRLGNNILHSAMRRCDLPIILDIVKKDSTLLHKRNSERRNPFHQALHEMHTFPSSKETEEIHFMNLSDLLLKEGVDLNKKDIKGKTILDIALSKQYFHLCVKLMKAGAHTNISSPSKFLKNSDANSILERPFKFKNDLKKELDNNPLIAMAQINDLYVQIKNNRIRTPTGYAPKEGVSFFKGKSNDAKAHDEVLSVLKELYDSKLTEMLGNLPGEGLEEIKRSQKFFDGELKLLIKNQDISRKVDKKSIQEAVGTSLKLKW
What is the function of this protein?
Virulence effector that plays a role in hijacking the host vesicular trafficking by recruiting the small guanosine triphosphatase (GTPase) Rab1 to the cytosolic face of the Legionella-containing vacuole (LCVs).  Acts as a phosphocholine transferase by mediating the addition of phosphocholine to Ser residues of host RAB1 (RAB1A, RAB1B or RAB1C) and RAB35, leading to displacement of GDP dissociation inhibitors (GDI).  Phosphocholination of target proteins also impairs accessibility to GTPase effector LepB.  Can act on both GDP-bound and GTP-bound Rab proteins.
What are the official names of this protein?
Phosphocholine transferase AnkX, PC transferase, Ankyrin repeat-containing protein X.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Note=Translocated into the host cell via the type IV secretion system (T4SS).
Protein: TX105_LYCSI
Sequence: MMKVLVVVALLVTLISYSSSEGIDGLEADELLSLMANEQTRKECIPKHHECTSNKHGCCRGNFFKYKCQCTTVVTQDGEQTERCFCGTPPHHKAAELVVGFGKKIFG
What are the official names of this protein?
U1-lycotoxin-Ls1b, Toxin-like structure LSTX-A5.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 04 (U1-Lctx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: UXUA_STRA3
Sequence: MEMSFRWYGEDDPVTLENIGQIPTMKGIVTAIYDVPVGEVWSRERIQQLKEKVEAAGLKISVIESVPVHEDIKLGRPTRDLLIDNYIQTVKNLAAEGIDTICYNFMPVFDWTRTDLAYQYPDGSTALIFDETVSKKMDPVNGELSLPGWDASYSKEEMKAIMDAYAEIDEEKLWENLTYFIKRIIPEAEAVGVKMAIHPDDPPYSIFGLPRIITGLEAIERFVKLYDSKSNGITLCVGSYASDPQNDVLEISRRAFELDRVNFVHARNIKLGDGKSFKESAHPSEYGSIDMYEVIKLCHEFGFEGAIRPDHGRMIWGETGRPGYGLYDRALGATYLSGLYEAVIKGSK
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.
What are the official names of this protein?
Mannonate dehydratase, D-mannonate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the mannonate dehydratase family.
Protein: FADR_ECOLU
Sequence: MVIKAQSPAGFAEEYIIESIWNNRFPPGTILPAERELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTKVNNFWETSGLNILETLARLDHESVPQLIDNLLSVRTNISTIFIRTAFRQHPDKAQEVLATANEVADHADAFAELDYNIFRGLAFASGNPIYGLILNGMKGLYTRIGRHYFANPEARSLALGFYHKLSALCSEGAHDQVYETVRRYGHESGEIWHRMQKNLPGDLAIQGR
What is the function of this protein?
Multifunctional regulator of fatty acid metabolism.
What are the official names of this protein?
Fatty acid metabolism regulator protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPO4_PSEA6
Sequence: MRKIIHIDMDCYYAAVEMRDNPQYRDIPLAIGGSADRRGVISTCNYVARKYGVRSAMATAYARKLCPDLVLVPGRMALYSEISQQIRKIFLRYTDKIEPLSLDEAYLDVTDSELFSGSATLIAQDIRRAIFEETQLTASAGVAPCKFVAKIASDENKPNGICVITPDTQDAFVKTLALGKIPGVGKVTLQKLNNMGLFTCQDVRDYPLDAFVKAFGKFGPVIWDRSHGIDERELSVSRKRKSVGVERTLAQDITTDEECLAMLESLYPKLLSRLEAASPKLAIQSQGVKLKFNDFQQTTVEHRHQVLDKTYFKTLLSEALERRGTRGIRLVGLSVGLPETADVQQMVFNFEHEQNR
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YO105_YEAST
Sequence: MKKKISKVAALSRNMMLEIRLSKMRPILVATTLMLLHNLQFLTSAIMARTIITIIITSIITSRETVTILPPLIIEVHIQPKIINHIRDINQTKAIDITNEVNIYSPFF
What are the official names of this protein?
Uncharacterized protein YOR105W.
Protein: COL3_ARATH
Sequence: MASSSRLCDSCKSTAATLFCRADAAFLCGDCDGKIHTANKLASRHERVWLCEVCEQAPAHVTCKADAAALCVTCDRDIHSANPLSRRHERVPITPFYDAVGPAKSASSSVNFVDEDGGDVTASWLLAKEGIEITNLFSDLDYPKIEVTSEENSSGNDGVVPVQNKLFLNEDYFNFDLSASKISQQGFNFINQTVSTRTIDVPLVPESGGVTAEMTNTETPAVQLSPAEREARVLRYREKRKNRKFEKTIRYASRKAYAEMRPRIKGRFAKRTDSRENDGGDVGVYGGFGVVPSF
What are the official names of this protein?
Zinc finger protein CONSTANS-LIKE 3.
What is the protein family that this protein belongs to?
Belongs to the CONSTANS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CORZ_LOBRE
Sequence: QTFHYSQGWTN
What is the function of this protein?
Cardioactive peptide.  Corazonin is probably involved in the physiological regulation of the heart beat (By similarity).
What are the official names of this protein?
Corazonin.
What is the protein family that this protein belongs to?
Belongs to the corazonin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PUS4_ARATH
Sequence: MAKWRLATATLRRQLQSSSPTISTFKNPTKALSAAAHQSTRSYSTTQTDDSRGKWLTLPPFSPTIDGTAVGKDLLSDGDSVKSSTDNSKTTALRWILRCRPDLPRTLVQKLFRLRQVRREMSMSVDGDELQRSQLKRVAAKESLNVGDRIYLPLSVDNDTPQTPPAKKESFQCSDEERKFVCSLVLYKDPAIIVLNKPHGLAVQGGSGIKTSIDELAASCLKFDKSESPRLVHRLDRDCSGLLVLARTQTAATVLHSIFREKTTGASAYGVKKNVKSLKRKYMALVIGCPPRQRGQISAPLRKVVVDDGKSERITVNDNGELVSTQHAITEYRVIESSPHGYTWLELRPLTGRKHQLRVHCAEVLGTPIVGDYKYGWQAHKAREPFVSSENNPTKQSSSPFGLDLDGGDVSSKQPHLHLHSKQIDLPNISQLLEKMQVSSDSDISDLDSLKFDAPLPSHMQLSFNLLKSRVETCDKN
What are the official names of this protein?
RNA pseudouridine synthase 4, mitochondrial, RNA pseudouridylate synthase 4, RNA-uridine isomerase 4.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RluA family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: HUTH_RHOCS
Sequence: MTETLRLTPAGLTLADLRRVLAGPVRLEIAPRDLEAAEASARTVAEVIGSGRTVYGINTGFGLLARTRIEPDRLAQLQRNLVLSHAAGTGEAMPDRVVRLMLVLKVASLLRGFSGVRGEVIRALAALVSAEALPLVPAKGSVGASGDLAPLAHLVLPLLGLGQVRLAGRTVPAADGLAAAGLRPLELGPKEGLALLNGTQASTALALAGLVAAEWAFDAALVAGALSIDAAQGSDTPFDARIHALRGQRGQIDAAAGYRRLLAGSPIRASHLSCARVQDPYCLRCQPQVMGACLDQLRFAAGTLATEANAVTDNPLVFPDDGDILSGGNFHAEPVAMAADQIALALAEIGSLSERRTAMLVDPHHNGGLPAFLVTDGGLNSGFMIAQVTAAALASENKGLAHPASVDSIPTSANQEDHVSMATWAARRLLEMADNAAGIVAVELLAACQGIDFRRPLRTSAPLEAVHAAVREEVGFYDRDRHFAPDIEAARGLIAAGRAASGTDWLAAA
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAX_CAMHC
Sequence: MILCDIGNSTAKFYNNGISKVMSIKEFQKFEPKDTVYFINVNPNFKRKLKGTLFFDLAPYFEINTLYSKELGVDRIAASCAINDGIVIDAGSAITVDMVNKNIHMGGFILPGITKYVEAYKSISSVLDVGLNSQVNLDKIPLNTRDAITYGVVNSVVLLVENIAKNRKIYITGGDGQFLSQFFKNAVYDKNLVFRSMLNVIKSKGL
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDUI_SALG2
Sequence: MDVRQSIHSEHAKTLDTQALRREFLIENIFVADEYTMVYSHIDRIIVGGIMPVSHSVEIGGEVGKQLGVSRLLDRRELGVINIGGAGAIIVDGQRHDIGHRDALYIGKGAKELVFVSNEASRPAKFYYNCAPAHTAYPTKKVSPADVAPVTLGDNLTSNRRTINKYFVPDVLETCQLSMGLTELAPGNLWNTMPCHTHERRMEVYLYFNMEEDSCVFHMMGQPQETRHIVMRNEQAVISPSWSIHSGVGTKAYTFIWGMVGENQVFDDMDHVAVQDLR
What is the function of this protein?
Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.
What are the official names of this protein?
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase, 5-keto-4-deoxyuronate isomerase, DKI isomerase.
What is the protein family that this protein belongs to?
Belongs to the KduI family.
Protein: COAC1_MAIZE
Sequence: MSSSQESTFTSASAAAQVNASALDLLPVYAKELIAGGAAGAFAKTAVAPLERVKILLQTRTEGFQSLGILQSLRKLWQYEGIRGFYKGNGASVLRIVPYAALHYMTYEQYRCWILNNSASSIGTGPVVDLLAGSAAGGTAVLCTYPLDLARTKLAYQVSNVGQTGNALGNSGQQQTYNGIKDVFKTVYKEGGARSLYRGVGPTLIGILPYAGLKFYIYEDLKSQVPDDYKDSVILKLSCGALAGLFGQTLTYPLDVVRRQMQVQSKQSQNSSDGFRIRGTFQGLLLIIRCQGWRQLFAGLSLNYVKVVPSVAIGFTTYDMMKALLGVPPRERVHASGGNK
What is the function of this protein?
Required for the accumulation of coenzyme A in the mitochondrial matrix.
What are the official names of this protein?
Mitochondrial carrier protein CoAc1, Mitochondrial carrier family protein 2, Mitochondrial coenzyme A transporter CoAc1, ZmCoAc1.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MOAC_HELPJ
Sequence: MPLTHLNEENQPKMVDIGDKETTERIALASGRISMNKEAYDAIINHGVKKGPVLQTAIIAGIMAAKKTSELIPMCHPIMLNGVDIDILEEKETCSFKLYARVKTQAKTGVEMEALMSVSIGLLTIYDMVKVIDKSMTISGVMLEHKSGGKSGDYNAKK
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: GYRB_HALH5
Sequence: MTREQQAYDESQIQVLEGLEAVRKRPGMYIGSTSSRGLHHLVWEIVDNSIDEAMAGFCDEIGVVIEEDNSITVTDNGRGIPVGIHEKMGRPAVEVIMTVLHAGGKFGGGGYKVSGGLHGVGASVVNALSTMLEVEVHREGKVHYQKFHRGVPAADLEVIGTTDRTGTKIHFKPDGDIFTETTVFEYDTLASRLRELAFLNKGLRIKITDMREEEKSDEFHYEGGIASFVEHLNRTRETLHETPIHIEGEKQGVYVEIAVQYNDGFTSNIYSFANNINTHEGGTHESGFKTGLTRVINDYARKHNLFKESDPNLTGEDVREGLTAIISVKIPDPQFEGQTKTKLGNSEARTITDSLFTEHFSRFLIEHPQVARKLVDKGLMASRAREAAKKARELTRRKSALEVSSLPGKLADCSSRDASISEIYIVEGDSAGGSAKQGRDRHFQAILPLRGKILNVEKARLDKILANNEIRAIITALGTGIGDDFDIEKARYHKIIIMTDADVDGAHIRTLILTFFYRYMRPLIEHGYVYIAQPPLYKVQQGKDIQYAYGDAELQEILSQLPDKAKPGIQRYKGLGEMNPSQLWETTMDPGQRTVLQVTLEDAMKADEIFEILMGDRVEPRRDFIQENARYVKNLDI
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
Protein: TATA_BRUAB
Sequence: MGSFSIWHWLIVLAVVLLLFGRGKIPELMGDVAKGIKNFKQGMADEDAKEDPRTIDAKAEEPVKDVKKTTKS
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RL36_CORDI
Sequence: MKVRKSLRSLKNKPGAQVVRRRGKVYVINKKDPRFKARQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: SOSSC_DROPE
Sequence: MAFPTTSAQQAETNRKILEDIQTKKQLLAGGIINLGLSNTNQMPSPQLLGQPTVAPEFLPQGVGLPTNATPPRSAFNPTSSTTLGFFIPQDSYFGNSFIPVLPRLEPLPTTTAPATTTASHIAPK
What are the official names of this protein?
SOSS complex subunit C homolog.
What is the protein family that this protein belongs to?
Belongs to the SOSS-C family.
Protein: OM25_BRUCA
Sequence: MRTLKSLVIVSAALLPFSATAFAADAIQEQPPVPAPVEVAPQYSWAGGYTGLYLGYGWNKAKTSTVGSIKPDDWKAGAFAGWNFQKDQIVYGVEGDAGYSWAKKSKDGLEVKQGFEGSLRARVGYDLNPVMPYLTAGIAGSQIKLNNGLDGESKFRVGWTAGAGLEAKLTDNILGRVEYRYTQYSNKNYDLAGTTVRNKLDTQDIRVGIGYKF
What are the official names of this protein?
25 kDa outer-membrane immunogenic protein.
What is the protein family that this protein belongs to?
Belongs to the Omp25/RopB family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: PROT2_LYSEN
Sequence: MVAVVQADYSRAEALAAWTRLSDEFIGNCYVSVRPRHAPAWEVVVASAAGSLRLEAFKRAHDHDFLDRLAVAIGNWEQKAQRPDHEIAQMLDQVGDYGLMQGMTNPDKGFMHADILLPLLQARDACAIVVRTEPVFQQLGTAFLVRPDLILTAAHVVMDVDAATGRWASTLKNGLAFHFREKPNQREHPTLAIRPAAVALISHALPHGRPPNLLERSLAAPADTCLDYALIRLAQRVSHLRPVEVVDTAAVKQGKPCWAFGFPGGNALMMDVDLVTDIDPGSGRWLHRANVAAGMSGGCCINHEGQVAGLHEGTLDSEDDAKVKRNRGISIAAIRRDQCRDGKDPLKQVASSPSLEFRDPALVDGWYRAGTALAGEAGAAQWRASVEAALRGRNPDATDSLPAYHPWFARADVEKWIDSAAPDERLSLIHGPPGVGKSFCIHLLRGKLDPYADLVVFNPTQTNDMTWSDATGHAAAANASDYRTAAASVRYRAIDDFLGELRDRSAGGTRTCYVAIDFGPAGRQDRFVGTNWVELIAILAAAGWIRVMLIGLDDYERSVMIDRMESRPETDSVKIAESELAPITAAEFRTYAKHLASARGKPAPKQAEMAKYVDSAVVGVAEPMKMVAAVRAAIELEAALS
What is the function of this protein?
Possibly a dedicated protease for substrate gasdermin bGSDM; cleaves the bGSDM precursor, releasing the pore-forming moiety, which integrates into the membrane and triggers cell death.  Involved in defense against bacteriophages.  When this probable 4 gene operon (bGSDM-FE772_23060-FE772_23065-FE772_23070) is inserted into E. coli it provides nearly 100-fold protection against phages T5 and T6 and about 8-fold against phage T4.  The operon without bGSDM no longer protects against phage.
What are the official names of this protein?
Probable serine protease FE772_23065, Trypsin-like protease 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: GPMI_CELJU
Sequence: MSAKKPVVLLILDGYGYSERTKYNAVYAAQTPVYDNLWKTCPNTLIDTSGMAVGLPAGQMGNSEVGHTTIGAGRVVYQSFTRINKSISDGDFFTNPEYVKAIDSAIANDRAVHILGLLSEGGVHSHQDHLYAMINMAVERGAKQVYLHAFLDGRDTPPRSAEASLQKAQDVFAKLGTGRVASIVGRYFALDRDNRWDRVKTAYDVMVTGEAEFDALTAVDGLKAAYERGENDEFVKATVICGEDEEVATINDGDSVIFMNFRPDRAREITRALIDENFTGFDRGETHPAIAHFVQTTEYASDIKAPIAFPPEDLSNSFGEYIAGLGKTQLRIAETEKYAHVTFFFNGGNEVVYPGEDRILVPSPKVATYDLQPEMSAPEVTDKLVEAIESGKYDAIICNYANCDMVGHSGLFDAAVKAVEAVDVALGRVLAAVKKVDGEALITADHGNVEEMFDEETGQPHTQHSTLPVPFIFVSSRKGKLASGGSLADVAPTILALMDLPQPKEMTGRNLITLEG
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: PURL_LIMRD
Sequence: MKQAMTPEEIKEKKPYLDWSLTEAEYDYIRTQLLGRLPNYTETGLFSAMWSEHCSYKKSKPVLRLFPNKNERVLQGPGEGAGVVDIDDGQAVVFKAESHNHPTTVEPYQGAATGVGGILRDIFSMGARPIASLDSLHFGELDNSTTRMKVTNTVRGIGDYGNCMGIPTIAGETTFDPCYQGNILCNAMSVGLMDQKDIQQGRAAGIGNAVMYVGAKTGRDGIHGATFASADFNDENMTQRSAVQVGNPFMEKLLLEACLDLIRNHPDWLVGIQDMGAAGIVSSSAEMASEGQSGMELNLDLVPQREPGMSAYEIMLSESQERMLLCVKKGHEEDVKKIFDFYDLEAVTIGRITAGHDYVLFHDGEEVCHIPVSSLTDDVLEEESLEKKPARIELAEQQPAWIPDIDNVAEVLTALLAQSTIADKSSLYQQYDSQVRTNTVAGPGSDAGVLRIRGTHKGLAMTTDGNGRFVYLSPEVGGQIALVEAAANIIASGAEPLAITDCLNYGDPTDPEIFWELHQSVQGMADACREFNTPVISGNVSLYNENNGQAIHPTPMVGMVGLIKNIDRVIPSFVQHPGDKVYLVGQTRDDYAGSELQKMMTGDISGIVESFDLHHVHQYMQRLLTTMENGLVSSAHDLSEGGLGVALAETVFKTDLGLKIDLADQHTARLFSETPGRFIVTVAPEKATEFEQVLGKDAHLIGEVTNSHWLMVKLANGELNENVAKLQETWEEAIPCQLKSKD
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CFA68_HUMAN
Sequence: MAASQCLCCSKFLFQRQNLACFLTNPHCGSLVNADGHGEVWTDWNNMSKFFQYGWRCTTNENTYSNRTLMGNWNQERYDLRNIVQPKPLPSQFGHYFETTYDTSYNNKMPLSTHRFKREPHWFPGHQPELDPPRYKCTEKSTYMNSYSKP
What is the function of this protein?
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.
What are the official names of this protein?
Cilia- and flagella-associated protein 68.
What is the protein family that this protein belongs to?
Belongs to the CFAP68 family.
Protein: POK9_HUMAN
Sequence: MGQTKSKIKSKYASYLSFIKILLKRGGVKVSTKNLIKLFQIIEQFCPWFPEQGTLDLKDWKRIGKELKQAGRKGNIIPLTVWNDWAIIKAALEPFQTEEDSISVSDAPGSGIIDCNEKTRKKSQKETESLHCEYVAEPVMAQSTQNVDYNQLQEVIYPETLKLEGKGPELVGPSESKPRGTSPLPAGQVPVTLQPQKQVKENKTQPPVAYQYWPPAELQYRPPPESQYGYPGMPPAPQGRAPYPQPPTRRLNPTAPPSRQGSELHEIIDKSRKEGDTEAWQFPVTLEPMPPGEGAQEGEPPTVEARYKSFSIKILKDMKEGVKQYGPNSPYMRTLLDSIAHGHRLIPYDWEILAKSSLSPSQFLQFKTWWIDGVQEQVRRNRAANPPVNIDADQLLGIGQNWSTISQQALMQNEAIEQVRAICLRAWEKIQDPGSTCPSFNTVRQGSKEPYPDFVARLQDVAQKSIADEKARKVIVELMAYENANPECQSAIKPLKGKVPAGSDVISEYVKACDGIGGAMHKAMLMAQAITGVVLGGQVRTFGGKCYNCGQIGHLKKNCPVLNKQNITIQATTTGREPPDLCPRCKKGKHWASQCRSKFDKNGQPLSGNEQRGQPQAPQQTGAFPIQPFVPQGFQGQQPPLSQVFQGISQLPQYNNCPPPQVAVQQVDLCTIQAVSLLPGEPPQKIPTGVYGPLPEGTVGLILGRSSLNLKGVQIHTSVVDSDYKGEIQLVISSSVPWSASPGDRIAQLLLLPYIKGGNSEIKRIGGLGSTDPTGKAAYWASQVSENRPVCKAIIQGKQFEGLVDTGADVSIIALNQWPKNWPKQKAVTGLVGIGTASEVYQSMEILHCLGPDNQESTVQPMITSIPLNLWGRDLLQQWGAEITMPAPLYSPTSQKIMTKRGYIPGKGLGKNEDGIKIPFEAKINQKREGIGYPFLGAATIEPPKPIPLTWKTEKPVWVNQWPLPKQKLEALHLLANEQLEKGHIEPSFSPWNSPVFVIQKKSGKWRMLTDLRAVNAVIQPMGPLQPGLPSPAMIPKDWPLIIIDLKDCFFTIPLAEQDCEKFAFTIPAINNKEPATRFQWKVLPQGMLNSPTICQTFVGRALQPVKVFRLLYYSLY
What is the function of this protein?
Early post-infection, the reverse transcriptase converts the viral RNA genome into double-stranded viral DNA.  The RNase H domain of the reverse transcriptase performs two functions.  It degrades the RNA template and specifically removes the RNA primer from the RNA/DNA hybrid.  Following nuclear import, the integrase catalyzes the insertion of the linear, double-stranded viral DNA into the host cell chromosome.  Endogenous Pol proteins may have kept, lost or modified their original function during evolution (By similarity).
What are the official names of this protein?
Endogenous retrovirus group K member 9 Pol protein, HERV-K(C6) Gag-Pol protein, HERV-K109 Gag-Pol protein, HERV-K_6q14.1 provirus ancestral Gag-Pol polyprotein.
What is the protein family that this protein belongs to?
Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.
What are the subcellular locations of this protein?
Cell membrane. Note=Cytoplasmic membrane (in a transfection system).
Protein: LGT_STRP2
Sequence: MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPDDILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLYIFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMYIEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMRTDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BETI_BURP6
Sequence: MPKLGMREIRRAQLIDATLRSIDEAGLPGTTLASVAQRANISTGIVSHYFGDKDGLLEATMRHVLRDLWAATTRRRAAASDAPRARLRAVVAANFDDTQISAPVMKTWLAFWSQSMHEPTLRRLQRVNTRRLHSNLCAEFAKTLPRARAREAASGLAALIDGLWLRGALAGEPLDTKAALKLANDYIDQLLAPRV
What is the function of this protein?
Repressor involved in the biosynthesis of the osmoprotectant glycine betaine.  It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator BetI.
Protein: FLIE_SALPA
Sequence: MAAIQGIEGVISQLQATAMAARGQDTHSQSTVSFAGQLHAALDRISDRQTAARVQAEKFTLGEPGIALNDVMADMQKASVSMQMGIQVRNKLVAAYQEVMSMQV
What are the official names of this protein?
Flagellar hook-basal body complex protein FliE.
What is the protein family that this protein belongs to?
Belongs to the FliE family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: GLYA_STRP1
Sequence: MIFDKGNVEDFDKELWDAIHAEEERQEHHIELIASENMVSKAVMAAQGSVLTNKYAEGYPGNRYYGGTECVDIVETLAIERAKKLFGAAFANVQAHSGSQANAAAYMALIEAGDTVLGMDLAAGGHLTHGSPVNFSGKTYHFVGYSVDTDTEMLNYEAILEQAKAVQPKLIVAGASAYSRSIDFEKFRAIADHVGAYLMVDMAHIAGLVAAGVHPSPVPYAHIVTSTTHKTLRGPRGGLILTNDEALAKKINSAVFPGLQGGPLEHVIAAKAVAFKEALDPAFKDYAQAIIDNTAAMAAVFAQDDRFRLISGGTDNHVFLVDVTKVIANGKLAQNLLDEVNITLNKNAIPFETLSPFKTSGIRIGCAAITSRGMGVKESQTIARLIIKALVNHDQETILEEVRQEVRQLTDAFPLYKK
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.