PharMolix/UniProtQA huggingface dataset:
Protein: DNAA_BACAN
Sequence: MENISDLWNSALKELEKKVSKPSYETWLKSTTAHNLKKDVLTITAPNEFARDWLESHYSELISETLYDLTGAKLAIRFIIPQSQAEEEIDLPPAKPNAAQDDSNHLPQSMLNPKYTFDTFVIGSGNRFAHAASLAVAEAPAKAYNPLFIYGGVGLGKTHLMHAIGHYVIEHNPNAKVVYLSSEKFTNEFINSIRDNKAVDFRNKYRNVDVLLIDDIQFLAGKEQTQEEFFHTFNALHEESKQIVISSDRPPKEIPTLEDRLRSRFEWGLITDITPPDLETRIAILRKKAKAEGLDIPNEVMLYIANQIDSNIRELEGALIRVVAYSSLINKDINADLAAEALKDIIPNSKPKIISIYDIQKAVGDVYQVKLEDFKAKKRTKSVAFPRQIAMYLSRELTDSSLPKIGEEFGGRDHTTVIHAHEKISKLLKTDTQLQKQVEEINDILK
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMI_BUCBP
Sequence: MNAKNIKQTGILYIVPTPIGNLNDISYRAINILQHVDLIAAENIFHSQILLKHYNILTRTTSLNKDNEKIKSKTLIIQLKNKKNIALISNSGTPLINDPGFYLINECYNHIIKIVPIPGPCAAITALIASGLPANRFCYEGFLPSKQNSRCKILNQIKEEQRTIIFFEVTHRIIESITDIINILGPKRIITFAKELTKKWEIIQKNTSYNILIWLKQNYTYKKGEIVIIISGYNNKNTNLISDAVLKTLKILKTHLSFNKAIKITAGIYKLPKNYLYNYAINNTISKNNDIH
What is the function of this protein?
Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase I, 16S rRNA 2'-O-ribose C1402 methyltransferase, rRNA (cytidine-2'-O-)-methyltransferase RsmI.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHI2_ARAHY
Sequence: MTEQKPKPSCHNVMVGNYVPTASDRAANRTLGFGLVTNIINGGLDC
What is the function of this protein?
Defense against chitin-containing fungal and bacterial pathogens.
What are the official names of this protein?
Endochitinase 2, CHIT 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 19 family. Chitinase class I subfamily.
Protein: HTPG_BURCM
Sequence: MAHETMSFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDAADKLRFEGLADNALYENDPNLRIRIGFDKAARTITIDDNGIGMSRDEAIANLGTIARSGTKEFFTKLSGDQQKDAALIGQFGVGFYSGFIVADKITVETRRAGLPANEAVRWESAGEGDFTIDAIERAQRGTTITLHLREGEDELLSSHRLKSIIQKYSDHIALPILMQKEEWDQEKGEMVLKDEDETVNQASALWTRSKSDITDEQYTQFYQHVAHDHQDPLTWTHNRVEGRSEYTQLLFVPAHAPFDLWNRDYRGGLKLYVKRVFIMDDAEQLLPQYLRFVKGVVDSADLPLNVSREILQESRDVKAIREGVTKRALSMLEELANAEEEAGKEKYKTFWSAFGQVLKEGLGEDHANRERIAKLLRFASTHGDTDAQDVSLADYVSRMKPEQSKIYYVTADTWQAAKNSPHLEVFRKKGVEVLLLTDRVDEWMLSFLHEFDGKPLASVARGDLDLGELNDEEKKAQEQAGEAIKPVVEKMKEALGDKVKEVRVTFRLTDSPSCLVADDNDMSGYLQRMLKAAGQNAPAMQPILEINPEHALVKQLNADSASFGDWCHLLFDQALLAEGGMLDDPASFVKRTNALLLSRAA
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPO3_STAS1
Sequence: MAMTNEEKFKILADQIKITEHLDSEILENSELTRVDVKTSDRTWVFQITFPHFLTIENYLLFTGAIIEEFKTIADVKCNFTVKDKTNQDEFAIKYFSHCIDQTKLSPKVKGQLKQKRLIMSGDVLKVMCQNDVERDHFDKACNGSLIAAYQQCGFNISKVVFETDSAVNDGDLASLEAHIQEEDEKSAREATEKLEKMKAEKAKQQDNNESDVSKCQIGKPIQVENVRQIDSIIEEEFKAAVEGVIFDINLKELKSGRHIVELKVTDYTDSLVLKMFTRKNKDDLAHFKALSVGKWVRAQGRIEEDTFVRDLVMMMSDIEEIKKATKQDKAEDKRVEFHLHTSMSQMDGIPNISDYVDQAAKWGHKAIAVTDHNVVQAFPDAHSAAEKNGIKMIYGMEGMLVDDGVPIAYKPKDCDLKTATYVVFDVETTGLSNQYDKIIELAAVKVKDGEIIDKFERFSNPHERLSETIKNLTHISDDMLVDAPEIEEVLTEFKSWVGDAIFVAHNASFDMGFIDTGYEHVGIGASTNGVIDTLELSRTINTEYGKHGLNFLAKKYGVELTQHHRAIYDTEATAYMFIKMLKQLEALGVHNHQDINTSLSNEDAYKRARPNHVTLIVQNQDGLKNLFKIVSASLVQYYYRTPRIPRSLLDEYREGILVGSACDEGEVFTAVMQKDQSQVERIAKYYDFIEVQPPALYQDLIDRELVRDNETLHEIYNRLIRAGDVNNIPVIATGNAHYLNEHDAIARKILIAAQPGNPLNRSTLPKAHFRTTDEMLDELHFLGEEKAYELVVQNTNDLADKIERVVPIKDELFTPRMEGANEEIREMSYDNAKALYGDDLPQIVIDRLEKELESIIGNGFSVIYLISQRLVKKSLNDGYLVGSRGSVGSSFVATMTEITEVNPLPPHYICPECKQSEFFDDGSVGSGFDLPDKKCESCGCDLIKEGQDIPFETFLGFKGDKVPDIDLNFSGEYQPEAHNYTKELFGEDKVFRAGTIGTVAEKTAFGFVKGYLNDQGIHKRGAEIDRLVKGCTGVKRTTGQHPGGIIVVPDYMDIYDFTPVQFPADDQGSSWMTTHFDFHSIHDNVLKLDILGHDDPTMIRMLQDLSGIDPKTIPVDDKETMGIFSSPEPLGVTSDEILCKTGTFGVPEFGTGFVRQMLEDTKPTTFSELVRISGLSHGTDVWLGNAQDLIRSGKCDLASVICCRDDIMVYLMYNGLEPSLAFKTMEFVRKGKGLTDDMVEAMVDNEVPDWYLDSCRKIKYMFPKAHAAAYVLMAVRIAYFKVHYPLYYYASYFTVRASDFDLISMIKDKESIRNTVNDMYSRYMDLAKKEKDTLTVLEIMNEMAQRGYRMQPISLEKSKAFEFIIEGDTLIPPFIAVPGLGENVAQRIVEARDEGPFLSKEDLNKKAGLSQKVIEYLDELGSLPNLPDKAQLSIFDM
What is the function of this protein?
Required for replicative DNA synthesis.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.
What are the official names of this protein?
DNA polymerase III PolC-type, PolIII.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. PolC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y939_HAEIN
Sequence: MMKVLLKGQTLLALMISLSLSSLLLLSISHFYVQIQTQNQHMLLHLKLQAELQRTLQLIGKDLRRLGFRALNAKLTESNLSLFELDEQGTAIFISQEDNAPPNSCVLFFYDLNKNGCIGKGSPKTCMKKGKNTSKSSTEELFGYKVSNKMIKTKLTYQSVIPTNCTAETCKRAFQQTACNAGGGWADLLDNNEYEITRLQFNWLIEGKGLEIKLKGNLKQTPNISYETSLVVVLWNQK
What are the official names of this protein?
Uncharacterized protein HI_0939.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: TOP6A_SACSH
Sequence: MSSEFISKVDKEARRKAANILRDKFLNLVEQLKKGEPLVMEIPMRTLSNAIYDEKRKLLLLGEKKLRRNFLDLNEAKRFMQTVLMASIIYDALVSDEYPTIRDLYYRGKHSLLLKSIEGNKIVSEENTWDEQKESDSVIVDIEVFTSLLREEMLILSKEKGKVVGNLRIRSGNDVIDLSKTGHGAYAIEPTPDLIDFIDVDAEFVLVVEKDAVFQQLHRAGFWKQYKSILITSAGQPDRATRRFVRRLNEELKLPVYILTDADPYGWYIFSVFRIGSISLSYESERLATPDAKFLGVSMGDIFGNSRKKPYLSEAERKNYIIKAKDADIKRAEEIKNYEWFKTKAWQEEINTFLQRKAKLEIEAMASKGLKFLAFQYIPEKITNKDYIA
What is the function of this protein?
Relaxes both positive and negative supercoils and exhibits a strong decatenase and unknotting activity; it cannot introduce DNA supercoils (PubMed:7961685).  ATP is absolutely required for DNA cleavage; the nonhydrolyzable analog AMP-PNP generates nicked or linear products from a supercoiled dsDNA substrate.  Generates staggered two-nucleotide long 5' overhangs.  The enzyme is covalently attached transiently to the 5'-ends of the cleaved strands (PubMed:11485995).
What are the official names of this protein?
Type 2 DNA topoisomerase 6 subunit A, Type II DNA topoisomerase VI subunit A.
What is the protein family that this protein belongs to?
Belongs to the TOP6A family.
Protein: DAAF3_MOUSE
Sequence: MTTPAGSGTGYGSVSWWGLSPALDLQAESPPVDPDSQSKTERKVPELDALLLGSVDGRHMLRTLARAALWPLRSFNFYVLENNLEAVARHMLIFSLALEEPEKMGLQERSETFLELWGNALLRPSVAAFLRAQASHLANLVLEPDRLEEQLPWLSLRLLKFRERDALEAVFRFWSGGEKGPEVFPMSRLWDSRLRHYLGSRYDARRGVADWDLRMKLHDRGAQVIHIQEFRRWRDTGVAFELRDLSAYHVPNRTLASGRLLSHRGERVAARGYWGDIATGPFMAFGIEADDQSLLRTRNGQPVKTASEITQHNVTELFREVAAWRGPRAIQGNVEETESPEPDVPAQEPFTIHFLPLDSSQTLHHKTCYQGRFQLLYVSCGMVHLLSPELGACVAPGGNLVVELARYLVDLRPKELKAFSDRVVEIARVAGFAPHTATKPSETFARFYKLGDSTPGGGDSAVESGPAPSKVESTRAPLPESISPPQANQAPSLEAMSPPLADLAPPLETMCPPQANQAPPLEALSPSKADQIPPLEAMSPPQAKLVLPVEAISLPQADLASPPEVISPLQEAMATSWVNAPPKHVT
What is the function of this protein?
Required for the assembly of axonemal inner and outer dynein arms.  Involved in preassembly of dyneins into complexes before their transport into cilia (By similarity).
What are the official names of this protein?
Dynein axonemal assembly factor 3.
What is the protein family that this protein belongs to?
Belongs to the DNAAF3 family.
What are the subcellular locations of this protein?
Cytoplasm. Dynein axonemal particle.
Protein: XNI_SALPB
Sequence: MAAHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIIHSQPTHAVAVFDDDARSSGWRHQRLPDYKAGRPPMPDDLHNEMPALRAAFEQRGVRCWASDGNEADDLAATLALKVTEAGHQATIVSTDKGYCQLLSPGLRIRDYFQKRWLDAPFIEKEFGVLPRQLPDYWGLAGISSSKVPGVAGIGPKSATQLLIQFQNLEGIYAHLDEVPEKWRKKLETHKEMAFLCRDIARLQTDLHIDGNLQQLRLAR
What is the function of this protein?
Has flap endonuclease activity.  During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.
What are the official names of this protein?
Flap endonuclease Xni, FEN.
What is the protein family that this protein belongs to?
Belongs to the Xni family.
Protein: MON2_SCHPO
Sequence: MSLYDSLLSNLQSINVDTRKKNADLKKLADGSLKFLYTNKNLSQDSLVSKLKGNEAFYKPFLFCCAKKIERHIYISLNSIQLLAINDALSPDILESLFNSLNAVIQLGQDSQLRVLQIIPIICTHYAASMKLPILISLFRICFNLHNSKNSVVSNAAAATLRQIVILVFDYLDYDTLAHKQEADLFLDSLSLFKGLCSLLSAGKSESLNVDHISTTFGLELLESILVNHHRLFQIPEFQDSVRKDLLPIITASLASMSDFPVALRISRILNIIFQHYVTSLTLDIEVIFSFIISSLDNSEAAWKKALFLEVLRSIFSNTNLLYLMYTLFDGNEGRKPIIKKLVTSLSRIVNEKPSVIGVGSRVVLADTFEDYSSTSSGNPPSSMEKVSGSFTGTKPEQIIGICRATILKTPCIEQFDKQEPPIIPFAYLVYLAMCSLASISNGIADFVFQFYEDVGKKEFTLLIEGIKCENFDSKEDSTARPQNIIKCQYGLISENWTSFLVAYSTFVSSALAVELLKFCLNSYVNFVSVCTLFGLETPRDALLTTLSNKAVPSNLLSGNMTHSASSSISHNGRLSTSTMFSVEGLKEAATTIAAIASYDSNHDEKQKCFSLREILFLRCLSSIAKVVGEKMGKGWKILFETFDKADIILNRSPTSKHLSTSSLNRVNSSNSNFQDSKSFSTLMDYELVSYKNELSELMYVTSSYSQPAYMEFLESLLAVITSSSVHPIQTLTAPRQSFNEDLLSANTKNSVYKTSANRSISGGIRLLRKSSEVFYSFSILETVCSCNLDRFLDSKLDHSGWSLISKSLSEVFKIINVAPELRTRAANCLANILVDVASRLSNENSPDSYAFQEIFFESLGMLLPVTEVSDNTSRGVEYDISTIGLEALVSILETVGHHVLHGWQYVFEMLRFNCLNGATCFGSEKGAKIVRLAFSCLQLICTDFLASLDTSNYLDLMDTLLVFCRQLEDANVSLTAVGLFWNVSDTLKNMFSTSDFSCAYNSVEDLYAFTSMKSKEILPEVLWIMLLVHLADLCENSWASVRNGAAQILFRIFNSQCSKLGTNAWASCCQLVIMKLLHSQPIQNVSDVNNKKDEDDHEQTSCLIISGIADVFSENMSLLLNVNGILDVLEEAFQLMLRLHSDIYPKICISNFKALRELSFSISEFGKENATFTLLIKLVFINWGRFCEVSFSERRLANISQEGLTLLIESVVFLLKAYNFGIEEIKDSLLQVRKAVFYEESTSFALDVDFLSSLQLAVESLTDLLISKFKLNHLVLELWSDVLTYAFNEEKTIRASLPTLICLSKKIFENAENVVENHSLDFLNRGTMQHMFESLLVPMRLKYRCPKASRVNQSTLPIWVLASKCFVRLMINCFKDLKGSDAIEDAEKMQCLFLLTVEATNSIISPNADYEYVWSLEDVFENEDVSSLKQLHNLWKPHLQLNCLSDEVAQYYITLCKGSFYYQMRNTEDMVISRSNLDIQKEAARNFFPSTESPVSNRRQRIAVDCFSILLDDYNSSYEHVSLTIRPILQSRLCWSLKRYVADKSVSGYLPLSKSQEMDMSTVAECLNNHPSLYSNPIHYLLRKAYHTTNASPVATSLNAILGQLTLKNEVLNAI
What is the function of this protein?
Required for traffic between late Golgi and early endosomes.  Required for endocytosis and maintenance of vacuolar structure (By similarity).
What are the official names of this protein?
Protein MON2 homolog.
What is the protein family that this protein belongs to?
Belongs to the MON2 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein. Note=Late Golgi.
Protein: RL6_NITSB
Sequence: MSRIGKQPVAIPSGVDVKIENGKIIAKKGNLTQEVEFGNRVNVSIEDNKIVFSPVGEDKQSKAFWGTYRALTNNAIEGLTKGFEKKLEINGVGYRAAVKGKELELQLGFSHPILYPIPEGIQISVEKNIITIKGHDKQKVGQVAAEIRSFRPPEPYKGKGVKYVDEVIIRKAGKTAKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: MGRB_SHIF8
Sequence: MKKFRWVVLVVVVLACLLLWAQVFNMMCDQDVQFFSGICAINQFIPW
What is the function of this protein?
PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing.  MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway.  Represses PhoP/PhoQ signaling, possibly by binding to the periplasmic domain of PhoQ, altering its activity and that of downstream effector PhoP.
What are the official names of this protein?
PhoP/PhoQ regulator MgrB.
What is the protein family that this protein belongs to?
Belongs to the MgrB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: CYB_PTEMA
Sequence: MTNIRKTHPLLKIINDSLVDLPVPSSVSSWWNFGSLLAACLAVQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWILRYLHANGASMFFICLYIHVGRGLYYGSYMYSETWNIGILLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTELVQWIWGGFSVDKATLTRFFAFHFLLPFIIAALVVVHLLFLHETGSSNPTGIPSDPDMVPFHPYHTIKDILGILMMLTMLSMLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILAVIPLLHTSKQRTMMFRPLSQCLFWLLAADLLTLTWIGGQPVEHPYIIIGQAASVLYFTIILLLMPLTSIMENHLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: OPAE_ASPUT
Sequence: MGPLRVFTDNKVKVMLLNPIGGAGFNDFVVETVLNHKDPSTHVTITSLANRIGGNQTLAYPSIRPLLYGEMIRVCLQARKENYDVLIINCFGDPMVDELQQIAGDDMVILGARQVAVQTASKISSKYAVLLPYDMKSSPDPLHQRVVADTRTAVAHPVVDMAFNDDLTPMDGESLGERLATQGKLAIKENGAEVLVLGCTAMVGCWQGLMRAVGVPVIDPTVAALRAAGKAGRLKRELVGGASTKRSGTFPTEKELKMIAESEPSYPFSGRIEI
What is the function of this protein?
Epimerase; part of the gene cluster that mediates the biosynthesis of oxepinamides, derivatives of anthranilyl-containing tripeptides that share an oxepin ring and a fused pyrimidinone moiety (PubMed:33004788).  The nonribosomal peptide synthetase (NRPS) opaA assembles the quinazolinone core with D-Phe incorporation (PubMed:33004788).  The first adenylation domain (A1) of opaA loads and activates anthranilic acid whereas the second A domain (A2) is for activating of L-Phe, which is then converted to D-form by the E domain (PubMed:33004788).  The third A domain (A3) is responsible for L-Ile activation and the terminal condensation domain C3 for cyclization and releasing the NRPS product protuboxepin K (PubMed:33004788).  The cytochrome P450 monooxygenase opaB then catalyzes alone the oxepin ring formation to convert protuboxepin K into protuboxepin A (PubMed:33004788).  The flavoenzyme opaC installs subsequently one hydroxyl group at the oxepin ring, accompanied by double bond migration, to form 15-epi-oxepinamide E (PubMed:33004788).  The epimerase opaE changes the D-Phe residue back to L-form, leading to oxepinamide E, which is further methylated at the hydroxyl group at C-12 by the O-methyltransferase OpaF to yield oxepinamide F (PubMed:33004788).
What are the official names of this protein?
Epimerase opaE, Oxepinamide F biosynthesis cluster protein E.
What is the protein family that this protein belongs to?
Belongs to the HyuE racemase family.
Protein: PYRI_NEIG1
Sequence: MEAQKLSVEAIEKGTVIDHIPAGRGLTILRQFKLLHYGNAVTVGFNLPSKTQGSKDIIKIKGVCLDDKAADRLALFAPEAVVNTIDNFKVVQKRHLTLPDEIAEVFRCPNPNCAGHGEPVKSRFYVKKHNGQTRLKCHYCEKTYNRDSVAEA
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: PXYP1_RAT
Sequence: MLYRNRFLVLLALAGLLAFLSLSLQFFHLIPVSTTKNGGSSKSRKRIMPDPVTEPPTVDPVYEALLYCNIPSVAEHSMEGHAPHHYKLVSVHVFIRHGDRYPLYAIPKTKRPEIDCTLVASRKPYHPKLEAFVGHMLKGSGASFESPLGSLPLYPNHPLCEMGELTQTGVVQHLQNGQLLRDIYLRKHKLLPNNWSSDQLYLETTGKSRTLQSGLALLYGFLPEFDWKKVYFKHQPSALFCSGSCYCPLRNQYLEKEQRRQYLLRLKNSDLERTYGEMAKIVDIPTKQLRAANPIDSMLCHFCHNVSFPCSRSGCLGMEHFKVIKTHQIEDERERHEKLLYFGYSLLGAHPILNQTVNRMQRAALGWRDELFTLYSAHDVTLSPILSALGLLEARFPRFAARLVFELWQDRQKPSEHSVRILYNGADVTFHTSFCHDFHKHSPKPMCPLENLVRFVKRDMFVALDGSSTNYYDACHGEGA
What is the function of this protein?
Responsible for the 2-O-dephosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans thereby regulating the amount of mature glycosaminoglycan (GAG) chains.  Sulfated glycosaminoglycans (GAGs), including heparan sulfate and chondroitin sulfate, are synthesized on the so-called common GAG-protein linkage region (GlcUAbeta1-3Galbeta1-3Galbeta1-4Xylbeta1-O-Ser) of core proteins, which is formed by the stepwise addition of monosaccharide residues by the respective specific glycosyltransferases.  Xylose 2-O-dephosphorylation during completion of linkage region formation is a prerequisite for the initiation and efficient elongation of the repeating disaccharide region of GAG chains.
What are the official names of this protein?
2-phosphoxylose phosphatase 1, Acid phosphatase-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the histidine acid phosphatase family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein. Note=Colocalizes to Golgi apparatus in a B3GAT3- dependent manner.
Protein: EF1A2_BOVIN
Sequence: MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETTKYYITIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPAYSEKRYDEIVKEVSAYIKKIGYNPATVPFVPISGWHGDNMLEPSPNMPWFKGWKVERKEGNASGVSLLEALDTILPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGILRPGMVVTFAPVNITTEVKSVEMHHEALSEALPGDNVGFNVKNVSVKDIRRGNVCGDSKSDPPQEAAQFTSQVIILNHPGQISAGYSPVIDCHTAHIACKFAELKEKIDRRSGKKLEDNPKSLKSGDAAIVEMVPGKPMCVESFSQYPPLGRFAVRDMRQTVAVGVIKNVEKKSGGAGKVTKSAQKAQKAGK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha 2, EF-1-alpha-2, Eukaryotic elongation factor 1 A-2, eEF1A-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SDA1_XENTR
Sequence: MSGRNNNKLPTNLPQLQNLIKRDPTSYREEFLQQYKHYLSVIEIFKLQPDKPNKELSTLVMFMAQTAHCFPQYLEDFPEQLKSLLRVHHTVMDPDQRMTLCKALILLRNKNLISPSVLLELFFELLRCQDKLLRKTLYTHIVTDIKNINAKHKNNKVNTTLQNFMYTMVRDNNAIAAKISLDVMIELYRRNIWNDAKTVNVISTSCFSKVTKILVAALKFFLGKDEEEKKDSDSESEDEGPTARDLMVRYSTGKKNTKNKKKLEKAMKVLKKHKKKKRPEVFNFSAIHLVHDPQEFAEKLLKQLEASKERFEVKLMHMDLISRLVGIHELFLFNFYPFVQRFLQPHQREVTKILLYAAQATHHLVPPEISQSVLRTIANNFVTDRNSGEVMTVGINAIKELTARCPLAMTEELLQDLALYKTHKDKNVSMSARSLIQLFRSLNPEMLQKKFRGKPTEASKEARIHAYGELDAKDYIPGAEVLEVEQEKTEEPEEDDGWESASLSDDDEDGEWIDVHHSSDEEQQEVADKIQAMPAEERKAKAATVSASRLLSQEDFKKIRLAQLAKEMNNAPGKSVKRKNIEIDSDEEERSGELLSLRDIEHLHKKPKSDKETRLATVMAGRTDRKEFVRKKSKMNPHASSTNKEKKKNKNFMMMRYSQNIRSKNKRSFRDKQIALRDSLLKKRKRLMK
What is the function of this protein?
Required for 60S pre-ribosomal subunits export to the cytoplasm.
What are the official names of this protein?
Protein SDA1 homolog, SDA1 domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the SDA1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: FLIE_SINMW
Sequence: MIDAIQSIGAFSAVKETEAAGSSSSASLATPGTGAAAPQAGSFAEVLGNMTTDAIRSVKSAEGVSLQAIRGEANTREVVDAVMSAEQSLQTAIAIRDKVVTAYLEIARMQI
What are the official names of this protein?
Flagellar hook-basal body complex protein FliE.
What is the protein family that this protein belongs to?
Belongs to the FliE family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: AROE_ACIB5
Sequence: MTKQFAVIGNPIEQSRSPELHHAFAEKTGVDLNYQKRLAPLDGFESSMRSFFAEGGSGMNVTVPFKEQAFALCDVLTERAQIAKAVNTLWMENGKLHGDNTDGQGLVAAIQALEWNLENTTILILGAGGATRGVIYPLVQAGAQKIVIANRTLARAEQLVDDLKTAVPQAQLQAISLNDLEGDFDIVINATSTSLSGDALQLPEKLQFKYAYEMAYGKPSSFIDQAKQRNVPYAEGFGMLVGQAIEAFYIWNGVRPQLKDFL
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: METK_BORPD
Sequence: MANNDFLFTSESVSEGHPDKVADQISDAILDAIFTQDPNARVAAETLCNTGLVVLAGEITTTANVDYIQVARDTIRRIGYDNTDYGIDYKGCAVLVAYDKQSPDIAQGVDRKSEDYLNQGAGDQGLMFGYACDETPDLMPAPIWYAHRLVQRQSELRKDGRLPWLRPDAKSQVTFRYVDGRPVEVDTVVLSTQHAPEISQSAIHEAVIEDIIKPSFPEGLITPRTKFLVNPTGRFVIGGPQGDCGLTGRKIIVDTYGGACPHGGGAFSGKDPSKVDRSAAYAARYVAKNVVAAGLARQCQVQVSYAIGVAEPINITVYTEGTGVIPDEQIAKLVREHFDLRPKGIVNMLDLLRPIYAKTAAYGHFGRAEPEFSWEATDKALELKKSA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_PYRFU
Sequence: MDWKGRDVISIRDFSKEDIEIVLSTAERLEKELKEKGQLEYARGKILATLFFEPSTRTRLSFESAMHRLGGAVIGFAEASTSSVKKGESLADTIKTVEQYSDVIVIRHPKEGAARLAAEVAEIPVINAGDGSNQHPTQTLLDLYTIRKEFGKIDGLKIGLLGDLKYGRTVHSLAEALAYYDVELYLISPELLRMPRHIVEELREKGVTVYETSDLMSVIGELDVLYVTRIQKERFPDEQEYLKVRGSYQVNLQVLSKAKETLKVMHPLPRVDEIHPEVDKTKHAIYFKQVFNGIPVRMALLGLVLGVI
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: BIOB_SODGM
Sequence: MSTSQRWTQAQARALFDKPFLELLFEAQQVHRQHFTPGEVQVSTLLSIKTGACPEDCKYCPQSARYSTGLESERLMQVQQVLDAARKARDAGSTRFCMGAAWKNPHDRDMPLLEQMVQGVKAMGLETCMTLGMLNDRQVQRLAEAGLDFYNHNLDTSPEFYGSIVTTRSYQDRLDTLSKVRQAGIKVCSGGIVGLGEDIRDRAGLLVQLANLPTPPESVPINMLVKVKGTPLADNEDVDPFEFIRTIAVARIMMPRSHVRLSAGREQMNEQTQALCFMAGANSVFYGCKLLTTPNPGEDRDMALFHKLGINIERRTATQGDVAQQAQLAEELLTADTAHYYNAAR
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: TX824_LYCSI
Sequence: MKLMIFTGLVLFAIVSLIEAQAENEKPCLPEYKVCTHAPGNCCSDLVCDRYGRYKSGAQIGRNCFCLQKGVIYKREN
What are the official names of this protein?
U8-lycotoxin-Ls1n, Toxin-like structure LSTX-H24.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 08 (U8-Lctx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: BXG1_BOMMO
Sequence: MKLIIFVVFCITIYGSTSGQQEVARRYCGRHLAVTMADLCFGVQFDKRNTQYEGYHWPLLAYSEERIKRQGIADECCLVPCTTNVLSSYC
What are the official names of this protein?
Bombyxin G-1, BBX-G1.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GLB3_CHITP
Sequence: LSADQISTVQASFDKVKGDPVGILYAVFKADPSIMAKFTQFAGKDLESIKGTAPFETHANRIVGFFSKIIGELPNIEADVNTFVASHKPRGVTHDQLNNFRAGFVSYMKAHTDFAGAEAAWGATLDTFFGMIFSKM
What are the official names of this protein?
Globin CTP-III, Erythrocruorin III.
What is the protein family that this protein belongs to?
Belongs to the globin family.