PharMolix/UniProtQA huggingface dataset:
Protein: MTNC_YERPG
Sequence: MIQAIVTDIEGTTTDIRFVHQVLFPYARERLTPFLRAHQQDDDIAALLVDLRREIAQPDADIETLITVLHGFMDEDRKSTVLKAIQGIIWRTGYLQADFRGHVYPEVAQQLADWHQQGLKLYVYSSGSVAAQKLLFGYSDAGDLCPLFSGYFDTHVGAKRDVSAYQKIANQLGIAPQALLFLSDIRQELDAAQLAGWHTCQLIRDLPDNDSAHPQVNRFDQIVLSLFTE
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
Protein: MDH_KLEVA
Sequence: SLYDIAPVTPGVAVDLSHIPTDVKIKGFSGEDATPALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKNLVQQIAKTCPQACIGVITNPVNTTVAIAAEVLKKAGVYDKNKLFGVTTLDIIRSNTFVAELKGKSATEVEVPVIGGHSGVTILPLLSQIPGVSFSDQEVADLTKRIQNAGTEVVEAKAGGGSATLSMGQAAARFGLSLVRAMQGEKGVVECAYVEGDGHYAR
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: RL33_SALA4
Sequence: MAKGIREKIKLVSSAGTGHFYTTTKNKRTKPEKLELKKFDPVVRQHVIYKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: VSP11_BORHE
Sequence: MRKRISAIIMTLFMVFMSCNNGGPELKSDEVAKSDGTVLDLAKVSKKIKEVSAFAASVKEVHTLIKSIGDLAKAIGKKIKTDETGTLESSTADQNEQLVAGAFQVVSTVKGELESLVQVDGISDDLKAKVNEAKNANDGLLSKFKSSAKDNESVKKDEEAKKVIDRTNASATELKKLDTAVDELLKAANEAVSAAIAELTAPAKS
What is the function of this protein?
The Vlp and Vsp proteins are antigenically distinct proteins, only one vlp or vsp gene is transcriptionally active at any one time.  Switching between these genes is a mechanism of host immune response evasion.
What are the official names of this protein?
Variable small protein 11.
What is the protein family that this protein belongs to?
Belongs to the variable small protein (Vsp) family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: YKP3_YEAST
Sequence: MEGKRNHQIIHSSDLFLTLVGNSSGTSSGSFWVQVVRWLRWLQVFVQFEDQWNTSWDVQLSNVSIRDTFQVLNQTSQGVTVSGDHDGLTTQQVLGNDILPVWQQSVNDQSQRFSFWQDIWVNVLVSFITLLREWRRSVDWGRWNIEGSSVGVEFFFTELLQSFSLVLTL
What are the official names of this protein?
Putative uncharacterized protein YKL153W.
Protein: METXA_RHILO
Sequence: MAALRAGKTNNEADQPSSPVLRFGADKPLKLDAGTLLSPFQIAYQTYGTLNDARSNAILVCHALTGDQHVANTNPVTGKPGWWEVLIGPGRIIDTNRFFVICSNVIGGCLGSTGPASTNPATGKPYGLDLPVITIRDMVRAQQMLIDHFGIEKLFCVLGGSMGGMQVLEWASSYPERVFSALPIATGARHSSQNIAFHEVGRQAVMADPDWHGGKYFENGKRPEKGLAVARMAAHITYLSEAALHRKFGRNLQDREALTFGFDADFQIESYLRHQGMTFVDRFDANSYLYMTRSMDYFDLAADHGGRLADAFAGTKTRFCLVSFTSDWLFPTEESRSIVHALNAAGASVSFVEIETDRGHDAFLLDEPELFAAINGFIGSAARARGLSA
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA_BRUA2
Sequence: MDRIKIVGGNKLNGVIPISGAKNAALPLMIASLLTDDTLTLENVPHLADVEQLIRILSNHGVDYSVNGRREHQNGPYSRTIHFTARNIVDTTAPYELVSRMRASFWVIGPLLARMGEANVSLPGGCAIGTRPVDLLLDALLALGAEIDIENGYAKAKARNGLVGARYKFPKVSVGATHVMLMAATLAKGETIIENAAREPEVANLADCLNAMGAKISGAGSSTIHVQGVTNLSGARVRIIPDRIEAGTYAMAVAMTGGDVLLEGAQESQLSCVLETLRQAGAEINETNSGLRVVRNGHGIQPVDITTDPFPGFPTDLQAQFMGLMTRAKGTSHITETIFENRFMHVQELARLGAKISLSGQTATVEGVERLKGAQVMATDLRASVSLVIAGLAAEGETIVNRVYHLDRGFERLEEKLSRCGADVKRISG
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P12_ASFK5
Sequence: MALDGSSGGGSNVETLLIVAIVVVIMAIMLYYFWWMPRQQQKKCSKAEECTCTNGSCSLKTS
What are the official names of this protein?
Inner membrane protein p12, Protein p12.
What is the protein family that this protein belongs to?
Belongs to the asfivirus inner membrane protein p12 family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass membrane protein. Note=Part of the virion inner membrane.
Protein: PEP5_YEAST
Sequence: MSLSSWRQFQLFENIPIRDPNFGGDSLLYSDPTLCAATIVDPQTLIIAVNSNIIKVVKLNQSQVIHEFQSFPHDFQITFLKVINGEFLVALAESIGKPSLIRVYKLEKLPNREQLYHSQVELKNGNNTYPISVVSISNDLSCIVVGFINGKIILIRGDISRDRGSQQRIIYEDPSKEPITALFLNNDATACFAATTSRILLFNTTGRNRGRPSLVLNSKNGLDLNCGSFNPATNEFICCLSNFIEFFSSSGKKHQFAFDLSLRKRIFCVDKDHILIVTEETGVPTTSISVNELSPTIINRIFIIDAKNKIISLNFVVSSAIIDIFSTSQSGKNITYLLTSEGVMHRITPKSLENQINIIIQKELYPFALQLAKQHSLSPLDVQEIHKKYGDYLFKKGLRKEATDQYIQCLDVVETSEIISKFGVKEVPDPESMRNLADYLWSLIKNSISQRDHVTLLLIVLIKLKDVEGIDTFIQHFDRKGIWNEGVVMDDMDDVTFFYSDNDFFDLDLILELMKESDFKRLSYRLAKKYSKDSLIIVDILLNLLHNPVKAIKYIKSLPIDETLRCLVTYSKKLLEESPNETNALLIEVFTGKFKPSTFEVDLDRRDTTGDFSENIRTVFYSYKTFFNYMNSNGTSDAMSESSEASHEHEEPTYHPPKPSIVFSSFVTKPFEFVVFLEACLACYQQYEGFDEDRQVILTTLYDLYLNLAQNDVPERIDDWRSRATGVLRESNKLVYSAASNNTSKRVDNSIMLLISHMDQSSASAKDKTKIDIASFANDNPEMDLLSTFRAMTLNEEPSTCLKFLEKYGTEEPKLLQVALSYFVSNKLIFKEMGGNEVLKEKVLRPIIEGERMPLLDIIKALSRTNVAHFGLIQDIIIDHVKTEDTEIKRNEKLIESYDKELKEKNKKLKNTINSDQPLHVPLKNQTCFMCRLTLDIPVVFFKCGHIYHQHCLNEEEDTLESERKLFKCPKCLVDLETSNKLFEAQHEVVEKNDLLNFALNSEEGSRDRFKVITEFLGRGAISYSDITI
What is the function of this protein?
Required for vacuolar biogenesis and for trafficking of hydrolase precursors to the vacuole.  Mediates transport at the vacuolar membrane where it may be responsible for tethering transport vesicles on the target membranes.  It is required for gluconeogenic growth of yeast.  Acts as component of the HOPS complex that acts during the docking stage of vacuole fusion.  HOPS is an effector for the vacuolar Rab GTPase YPT7 and is required for vacuolar SNARE complex assembly.  It remains bound to SNARE complexes after vacuole fusion (PubMed:3062374, PubMed:10978279, PubMed:10944212, PubMed:16601699).  Acts as component of the CORVET complex that is required for transport between endosome and vacuole.  CORVET is an effector for the endosomal Rab GTPase VPS21 (PubMed:17488625).  Probable ubiquitin-protein ligase involved in the degradation-related ubiquitination of histones.  Contributes to the post-translational regulation of histone protein levels by polyubiquitination of excess histones for subsequent degradation (PubMed:22570702).
What are the official names of this protein?
E3 ubiquitin-protein ligase PEP5, Carboxypeptidase Y-deficient protein 5, Histone E3 ligase PEP5, RING-type E3 ubiquitin transferase PEP5, Vacuolar biogenesis protein END1, Vacuolar morphogenesis protein 1, Vacuolar protein sorting-associated protein 11, Vacuolar protein-targeting protein 11.
What is the protein family that this protein belongs to?
Belongs to the VPS11 family.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y2214_ARCFU
Sequence: MSQQIDPQQIDPELKSGQIKVLLEQYKILKNEIHLTSQKMTGNIRIGLIVLSLIGSYILHSLIKNEITKSVIDNTTDAVMYTISILLIIGLWTNVFSSLSAIARLGGYLIYLEKTINELIGKNLMIYESEFVPKFFTGSAILAYDLPNVLVFGCTSLFVISFLGYKVLVTINTPDFNLILRSFIILILVISTILFLVNLFTILRVNKVKDEIVTFCTKKIK
What are the official names of this protein?
Uncharacterized protein AF_2214.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SSF2_YEAST
Sequence: MAKRRQKKRTHAQITPEQERDIPKSMVIRVGQTSLANHSLNQLVKDFRQIMQPHTAVKLKERKSNKLKDFVVMCGPLGVTHLFMFTQSEKTGNVSLKIARTPQGPTVTFQVLDYSLGRDIKKFLKRPKSLNNDDVLNPPLLVLNGFSTSKRSDEDDQDVNVEKVIVSMFQNIFPPLNPARTSLNSIKRIFMINKDRETGEISMRHYFIDIREVEISRNLKRLYKAKNNLSKTVPNLHRKEDISSLILDHDLGAYTSESEIEDDAIVRVVDNQDVKAKHSQTSLSQKTPVKMTDNEEREKGIEEEDVEMEEPKPSENSQPTPRKKAIKLTELGPRLTLKLVKIEDGICSGKVLHHEFVQKSSEEIKALEKRHAAKMRLKEQRRKEQEENIAKKKAVKDAKKQRKLERRKARAEEQGEGQGKDGAMSDDGSSSSEDEHYSDVPEDLDSDLFSEVE
What is the function of this protein?
Required for biogenesis of the 60S ribosomal subunit.
What are the official names of this protein?
Ribosome biogenesis protein SSF2.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: S13A2_HUMAN
Sequence: MATCWQALWAYRSYLIVFFVPILLLPLPILVPSKEAYCAYAIILMALFWCTEALPLAVTALFPLILFPMMGIVDASEVAVEYLKDSNLLFFGGLLVAIAVEHWNLHKRIALRVLLIVGVRPAPLILGFMLVTAFLSMWISNTATSAMMVPIAHAVLDQLHSSQASSNVEEGSNNPTFELQEPSPQKEVTKLDNGQALPVTSASSEGRAHLSQKHLHLTQCMSLCVCYSASIGGIATLTGTAPNLVLQGQINSLFPQNGNVVNFASWFSFAFPTMVILLLLAWLWLQILFLGFNFRKNFGIGEKMQEQQQAAYCVIQTEHRLLGPMTFAEKAISILFVILVLLWFTREPGFFLGWGNLAFPNAKGESMVSDGTVAIFIGIIMFIIPSKFPGLTQDPENPGKLKAPLGLLDWKTVNQKMPWNIVLLLGGGYALAKGSERSGLSEWLGNKLTPLQSVPAPAIAIILSLLVATFTECTSNVATTTIFLPILASMAQAICLHPLYVMLPCTLATSLAFMLPVATPPNAIVFSFGDLKVLDMARAGFLLNIIGVLIIALAINSWGIPLFSLHSFPSWAQSNTTAQCLPSLANTTTPSP
What is the function of this protein?
Low-affinity sodium-dicarboxylate cotransporter, that mediates the entry of citric acid cycle intermediates, such as succinate, citrate, fumarate and alpha-ketoglutarate (2-oxoglutarate) into the small intestine and renal proximal tubule (PubMed:10894787, PubMed:9668069, PubMed:8967342).  Transports the dicarboxylate into the cell with a probable stoichiometry of 3 Na(+) for 1 divalent dicarboxylate, rendering the process electrogenic (PubMed:8967342, PubMed:9668069, PubMed:10894787).  Citrate is transported in protonated form as a divalent anion, rather than the trivalent form which is normally found in blood (PubMed:10894787).  Has a critical role in renal dicarboxylate transport (By similarity).
What are the official names of this protein?
Solute carrier family 13 member 2, Na(+)/dicarboxylate cotransporter 1, NaDC-1, Renal sodium/dicarboxylate cotransporter.
What is the protein family that this protein belongs to?
Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ATPB_HAEIG
Sequence: MSAGKIVQIIGAVIDVEFPQDAVPKVYDALKVESGLTLEVQQQLGGGVVRCIALGTSDGLKRGLKVENTNNPIQVPVGTKTLGRIVNVLGEPIDEQGAIGEEERWAIHRSAPSYEEQSNSTELLETGIKVIDLICPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMKDSNVLDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDSTVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDVARGVQGILQRYKELKDIIAILGMDELSEEDKLVVARARKIERFLSQPFFVAEVFTGSPGKYVTLKDTIRGFKGILEGEYDHIPEQAFYMVGSIDEVLEKAKNM
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: COBC_SALTY
Sequence: MRLWLVRHGETEANVAGLYSGHAPTPLTEKGIGQAKTLHTLLRHAPFDRVLCSELERARHTARLVLEGRDVPQHILPELNEMYFGDWEMRHHRDLTHEDAESYAAWCTDWQNAVPTNGEGFQAFTRRVERFISRLDAFSDCQNLLIVSHQGVLSLLIARLLTMPAASLWHFRVEQGCWSAIDICEGFATLKVLNSRAVWRPE
What is the function of this protein?
Catalyzes the conversion of adenosylcobalamin 5'-phosphate to adenosylcobalamin (vitamin B12); involved in the assembly of the nucleotide loop of cobalamin.  Also catalyzes the hydrolysis of the phospho group from alpha-ribazole 5'-phosphate to form alpha-ribazole.
What are the official names of this protein?
Adenosylcobalamin/alpha-ribazole phosphatase, Adenosylcobalamin phosphatase, Alpha-ribazole-5'-phosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family.
Protein: ILVC_STRP4
Sequence: MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDVIIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPSLEAGNAVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYXDATGNAKNIXMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAGYAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMKAVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDDAFKIYN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: SYS_DICNV
Sequence: MIDPKLLRNDLPMVVAALARRGFDFPEAEYQKLEDLRKASQVKSETLQAERNKLSQQIGKAKSKGEDCADLMAQAAQLESEQAAVEASFNETQKQLDTLLSSVPNLPDDSVPTGKDENDNPEIRRWGTPRTFDFTPKEHADLMQIGLDFTNGVKLAGARFTVLRGALSRLHRAIAQFMLDTHTEEHGYQEMSVPYLVNPQTIYGTGQLPKFEQDLFKTRLSDRDFYLIPTAEVSLTNLVAQEILEESVLPLQFVAHTPCFRSEAGSAGRDVRGMIRQHQFDKVELVHITTPEDSHAALERLTAHAERILQKLELPYRVILLCTGDMGFAARKTYDLEVWLPGQGKYREISSCSNCWDFQARRMQARFRAEGEKRPQLVHTLNGSGLAVGRTLVAILENYQQADGNILIPKALQPYMNGLDRITPSA
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATK_SPICA
Sequence: MEEYQGYFELDGYQQHDFLYPLIFREYIYALAHDHGLNRSVLLDNVGYDNKSSLLIIKRLISRMYQQNHLIISANDSNQNKFFGYNKNLYSQIISEGFAVIVEIPFSLRSVSSLETTETEIVKSYNLRSLHSLFPFLEDKFPHLNYVSDVLIPYPIHLEILVQTLRYWVKDPSSLHLLRLFLHEYYNYNWNSLITPNKFIKSNPRLFLLLYNSHVCEYESIFLFLRNQSSHLRLTSYGIFFEQIHFYEKIKYPVENDFTVAILWFFKDPFMHYVRYQGKSILASKDTPLLMNKWKYYLVNLWQCHSYVWSQPGRIYINQLSKHSLYFLGYFSSMRPNLSVVRSQMLENSFIMDNAMKKLDTLVPIIPLIVSLAKVKFCNALGHPISKSTWADSSDFDIIDRFVRICRNISHYYSGSSRKKSLYRIKYILRLSCVKTLARKHKSTVRTFLKRFGSKLLEEFFTEEEQIRSLIFPRASYTLNKFYRGRIWYFDIFYINDLVNHE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NTPPA_KORVE
Sequence: MLRYNLGMGLILASASPRRSELLRKARMVFRVEPAHVPEVHTAGEDPKQYAQRLARDKARAVAAKYPNDFVIGADTIVVADAHVLEKPADEADAARMIRMLSGHTHEVTTGVCLCGPNVEIVETETTRVTVAEISDEEIADYIHTGEPMDKAGAYGIQGMFSRWVTGIEGDYFNVVGLPIARVYRMMRRAGVL
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIGL_RAT
Sequence: MEVVGLLCVAVAVLTWGFLRVWNSAERMRSPEQAGLPGAGSRALVVIAHPDDEAMFFAPTILGLARLKQQVSLLCFSSGNYYNQGEIRKKELLQSCAVLGIPPSRVMIIDKREFPDDPEVQWDTEHVASTILQHIHANATDLVVTFDAEGVSGHSNHIALYKAVRALHSGGKLPEGCSVLTLQSVNVLRKYVFLLDLPWTLLSPQGVLFVLTSKEVAQAKKAMSCHRSQLLWFRHLYTVFSRYMSVNSLQLL
What is the function of this protein?
Involved in the second step of GPI biosynthesis.  De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.
What are the official names of this protein?
N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase, Phosphatidylinositol-glycan biosynthesis class L protein, PIG-L.
What is the protein family that this protein belongs to?
Belongs to the PIGL family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: SYE_METB6
Sequence: MAGDEIKAALFLCALQNAVRHGGVPQAGAVIGMVMGAHPELRKQAKEVSAAAKDAIADVAALSPEERVTKLQSLSPEMFAALHEKHEKKKVLPDLEGAEHGVVMRFAPNPSGPLHIGHARAAALNDAYVKQYGGRYILRIEDTDPKRVDPEAYDMVKEDIAWMGLGITETVTQSERFPIYYDLCKQLIERGGAYVCTCENEHFKALKDAKKACPCRDQPVETALLLWEKMLNGGFKEGEASVRVKTDLLNPDPAMRDYPIFRILDAPLHPKIGDARVYPLMNFSVVADDHLLGVTHVIRGKDHIANTRRQRYIYDHFGWKVPVYRHYGRMGIEGVVLSTSQMHAGIDEGKYTGWDDIHLGTLRALARRGISPDAVKNAMIAIGIGDVDISFSWDNLYAENKKIVDPVANRYFFVPDPLEAKIAGASAHTAHAMLHPGHEEKGTRTLEFTGTVLIPRAEIFSVIVSSLNDISQGGDYESPQAKISSENVSPITSINEKKESVHSDNLPKLEGSLSSSLNDRKLVPRKYEPKREITMLRLKDLFNVNITWDGETPSFSYGGDSLADARAAKARIIQWLPAQSFVPCTLLTQDGEMKGACEPAVTTEVGKVVQFERIAFARIDAVTESGVRAYFTHT
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYDND_MAGSA
Sequence: MAATDTPWRPFRQAGALRRPMIDPAFVQGHPAYPDAFAQFFAGHGRYGHFAERVGNRNSRNGWRRRALAPGPAVGAEIVARHHEAAAQAGQGGDAARHQHRVDRLGQHHVRAAFEQVGRHFRLRGRSEHDRHRKGIVGADSPAHPPHQIARLLHAEIRVHHQKVDHFRPEVVFGIVAVVKAQQIPASQHAKGAGDDITAAEVEIAQQGAHTWGVVGHGLPSWQERTTFWPPAFRSPSDRSATSEFVAGLVNIGLSRLDKIWPGMPSSRFGFKRAYEGFMHVYRSHTCGQLKAADAGIQARLSGWVHRKRDHGNLLFVDLRDHYGITQCVIDVSSPVFAALDKARPESVITVTGKVVKRSAETINPRLPTGEIELQVAEVEIQSIADVLPIQVAGDQEYPEDMRLRYRFLDLRREDVHANMMLRSRVIAYLRQAMIGQGFTEFQTPILTASSPEGARDYLVPSRIHPGKFYALPQAPQQFKQLLMVAGFDKYFQIAPCFRDEAGRADRSPGEFYQLDFEMSYVTQDDVFAAIEPVLEGVFKEFGKGRAVTPAPFPRITYADSMLKYGSDKPDLRNPIIIADVTEPFRGSGFGLFAKLVDKGAVVRAIPAPGAAGQPRSWFDKLNDWARENGAGGLGYIQFAADGPKGPIAKNLEPARVEAIKAAANLKDGDAVFFACDKALPAAKFAGLVRTKIGNELDLLEKDVFKFCWTVDFPMYEINEETGLVEFSHNPFSMPQGGMDALLNQDPLTINAYQYDIVCNGVELSSGAIRNHRPDIMYKAFEIAGYSAAHVEEHFGGMLNAFKFGAPPHGGSAPGVDRIVMLLADQPNIREIILFPMNQQAQDLLMQAPAEIAMERLRELHIKVDLPKPKKEVKEG
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EZRA_BACAN
Sequence: MDSILTIVIIVVSSILVLLMIELVIRNRSYKDIEALEQWKQEIKDKPVADELKRVKDLNMTGQTEELFGKWREEWDEIVSTTIPKADKDLAQARKFASQFSFRKAKHAMNESISGLDDADNRITDILNELQQLLESHEKNSSEIEGLRDTYRSMKKSVLAHRHMYGAAEQKIEEMLDAESEKFKTFEEATNNGDYLKAREIVISLEEGLADLEIIIHQIPDLLVECQATLPVQLEDLLHGHNDMVRQGYVLDYLEVPKEVRDMTKQLQTCLIDIQELHITEAAEKVENLKTRLDGFYDQLEQEVHARHYVEQKTLSVYEDLEEIRTETIETKAETQLVKQSYQLQDKDIESQKVIEKQMHILTKRFEMLQLRVAEQDIAFSIIREELEEIYEQCETLKVLHAEYKEMLQTMRKEEFEAREKLQEMRNTIFETKRFMQKSNLPGLPESIMEDLKRGQMAMQAVYEQLEVKPLNMNAVNSSLEEAYTTVNGVAEMTEELIGQAYLVEKLIQYGNRYRSHDENLAESLNYAEKLFREYQYDAALEQAASVLEQLEPGVVQKIAEYVDNEQTLS
What is the function of this protein?
Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation.  Inhibits FtsZ ring formation at polar sites.  Interacts either with FtsZ or with one of its binding partners to promote depolymerization.
What are the official names of this protein?
Septation ring formation regulator EzrA.
What is the protein family that this protein belongs to?
Belongs to the EzrA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=Colocalized with FtsZ to the nascent septal site.
Protein: HISZ_BORPD
Sequence: MGNWLLPESLADVLPAEARRIEELRRELLDLYRTYGFELVAPPLVEYIDSLLSGTGTDLNLRTCKLVDQLSGRTLGVRADMTPQVTRIDAHLLNRAGVTRLCYCGTVLHARPADLLSSRELLQIGAEIYGHAGFEADLEILSLVLDTVAAAGLRQPRLDLCHPGVVRAILDADPAAAAYAEDIVLLLREKDVPGLAELARRDGGIRADTAAALQRLPGLYGGPDVLQQARHDLPLLPGVAAALDALQAIIDAMPDVTLGVDLADIGGYGYHSGVTFALYAEGWHDALVSGGRYDDVSRAFGRARPATGFSLDLRKLARGLPPAGRARAVRAPWGQDAALAAAVRQLRRAGEIVVQALPGHQQSQDEFICDRELVLQDGAWTLRTL
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YLM2_CAEEL
Sequence: MASSSSAALRPFGTARLTPGRQTGRQTQQQISAPEPMIAIALSDMEYLMRSARSSRSSGRSERQPGCTCCCHIAAGVTVIPRVARFSIEGGLSTHTLMNHSDNRIAVKITCSDNNMYRVTPVYATVEPGQSLPLHIARITSDLIKRDRLCVNILEADGNKEAREIFKKNANTRAPASINMALEATNDNQNHHHQE
What are the official names of this protein?
Uncharacterized protein D2007.2.
Protein: GNAS2_HUMAN
Sequence: MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs) (PubMed:17110384).  Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP (PubMed:26206488, PubMed:8702665).  GNAS functions downstream of several GPCRs, including beta-adrenergic receptors (PubMed:21488135).  Stimulates the Ras signaling pathway via RAPGEF2 (PubMed:12391161).
What are the official names of this protein?
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Adenylate cyclase-stimulating G alpha protein.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family. G(s) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.