PharMolix/UniProtQA huggingface dataset:
Protein: MCH_METFK
Sequence: MSESKLDVTLWPSVNQLTNPLVKHLVDNAKALRLLVEKLPSGATIIDAGIKAEGGLEAGRLIAEICMGGLGHVNLHSSSTFPHWPWTLSVHSNNPVLSCLGSQYAGWSLSHEKFFSLGSGPGRALAGREELYKELGYKDSADAAVLVLESDKVPPQEVIEKVARDTGVNPENLTFILTPTRSLAGTVQIVARVLEVALHKIHTLHFPLEHVVDGAASAPLPPPAPDFLIGMGRTNDAILFGGHAHIFVKGSDEAAAKLAKELPSSASRDYGRPFAEVFKAVNMDFYKIDPMLFSPAAVTVTAVESGKSFIGGKLDATLLDQSFGYSA
What is the function of this protein?
Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.
What are the official names of this protein?
Methenyltetrahydromethanopterin cyclohydrolase, Methenyl-H4MPT cyclohydrolase.
What is the protein family that this protein belongs to?
Belongs to the MCH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LDH1_STAA3
Sequence: MNKFKGNKVVLIGNGAVGSSYAFSLVNQSIVDELVIIDLDTEKVRGDVMDLKHATPYSPTTVRVKAGEYSDCHDADLVVICAGAAQKPGETRLDLVSKNLKIFKSIVGEVMASKFDGIFLVATNPVDILAYATWKFSGLPKERVIGSGTILDSARFRLLLSEAFDVAPRSVDAQIIGEHGDTELPVWSHANIAGQPLKTLLEQRPEGKAQIEQIFVQTRDAAYDIIQAKGATYYGVAMGLARITEAIFRNEDAVLTVSALLEGEYEEEDVYIGVPAVINRNGIRNVVEIPLNDEEQSKFAHSAKTLKDIMAEAEELK
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate (Potential).  Appears to be the primary factor that allows S. aureus growth during nitrosative stress in both aerobically and anaerobically cultured cells (By similarity).
What are the official names of this protein?
L-lactate dehydrogenase 1, L-LDH 1.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU5C_SOLLC
Sequence: MEQTYEYAWIIPFIPLPVPMLIGAGLILFPTATKRFRRMWAFQSVLLLSIVMIFSIYLSIQQINSSSVYQYVWSWIINNDFSLDFGYLIDPLTSIMSILITTVGIMVLIYSDNYMAHDQGYLRFFAYMSFFSTSMLGLVTSSNLIQIYIFWELVGLCSYLLIGFWFTRPVAANACQKAFVTNRVGDFGLLLGILGFYWITGSFEFRDLFEIFNNLIYNNELNFLFVTLCAVLLFAGAVAKSAQFPLHVWLPDAMEGPTPISALIHAATMVAAGIFLVARLLPLFRVIPYIMYLISVIGIITVLLGATLALAQKDIKRGLAYSTMSQLGYMMLALGMGSYRSALFHLITHAYSKALLFLGSGSIIHSMETIVGYSPAKSQNMGLMGGLRKHVPITKITFLLGTLSLCGIPPLACFWSKDEILNDSWLYSPIFAIIAWATAGLTAFYMFRIYLLTFEGHLNAHFQNYGGKQKIPFYSISLWGKNGVKKNSCLLTMNNNESTYFLSKTKYPIAKNGRKMTRPFMTIAHFKHKAVSSYPYESDNTMLFPIFVLGLFTLFVGAIGIPFNQEGVNLDILSKWLAPSINLLHPKSNNSLDWNEFLKDAVVSVSIAYFGIFIASFLYKPIYSSLKNLEFINSFVKKGPKRILWDKILNGIYDWSYNRAYIDAFYTRFFVGGIRGLAEFTHFVDRRVIDGMTNGVGVISFIVGEGIKYIGGGRISSYLFLYLAYVSVFLLVYYLLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 5, chloroplastic, NAD(P)H dehydrogenase subunit 5, NADH-plastoquinone oxidoreductase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: LUXS_STRP2
Sequence: MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLVQPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAVIKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: NUCL_CHICK
Sequence: MVKLAKTPKNQMKQKKMAPPPKKVEESEEEESSDLEESSGEEVMVPPKKQQKAAVTPAKKAATPAKKAATPAKKAVTPAKKAVATPAKKAVAPSPKKAAVVGKGAKNGKNAKKEESEEEDEDDEDDEEDEDEEEESDEEEEPAVPVKPAAKKSAAAVPAKKPAVVPAKQESEEEEEEDDEEEDEEDDESEDEAMDTTPAPVKKPTPAKATPAKAKAESEDEEDEEDEDEDEEDEDDEEEDEEESEDEKPVKEAPGKRKKEMANKSAPEAKKKKTETPASAFSLFVKNLTPTKDYEELRTAIKEFFGKKNLQVSEVRIGSSKRFGYVDFLSAEDMDKALQLNGKKLMGLEIKLEKAKSKESLKENKKERDARTLFVKNLPYRVTEDEMKNVFENALEVRLVLNKEGSSKGMAYIEFKTEAEAEKALEEKQGTEVDGRAMVIDYTGEKSQQESQKGGGERESKTLIVNNLSYAASEETLQELFKKATSIKMPQNNQGRPKGYAFVEFPTAEDAKEALNSCNNTEIEGRAIRLEFSSPSWQKGNMNARGGFNQQSKTLFVRGLSEDTTEETLRESFEGSISARIVTDRDTGSSKGFGFVDFSSPEDAKAAKEAMEDGEIDGNKVTLDFAKPKGEFQRGGGFGGGFGGRGGRGGRGGGRGGFGGRGGGRGFGGRGGGFRGGRGGGGDHKPQGKKIKFE
What is the function of this protein?
Nucleolin is the major nucleolar protein of growing eukaryotic cells.  It is found associated with intranucleolar chromatin and pre-ribosomal particles.  It induces chromatin decondensation by binding to histone H1.  It is thought to play a role in pre-rRNA transcription and ribosome assembly.
What are the official names of this protein?
Nucleolin, Protein C23.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: DPHB_HALWD
Sequence: MLTFIGLGLYDERSISIAGRDALQAADYVAAEFYTSYLVDATVSDLETAHDIDIDVRDREGVEQHPEDILRKAQSEDVAFLTAGDTMISTTHTDLRLRAIDRGIDTRVIHGVTAQTAASGLTGLQNYRFGKSVTLPFPYAHGAEGVPTSVTDSIAANRERGLHTVVYLDIKANRDEYLRASDAAEMLATDLEDMLAIAVARAGSPDPTVRADRLSALAEKDFGDPLHLLVLPGELHHLEEEALAALADAPADMLNAVDSQ
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine.  The three successive methylation reactions represent the second step of diphthamide biosynthesis.
What are the official names of this protein?
Diphthine synthase, Diphthamide biosynthesis methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the diphthine synthase family.
Protein: LRIT2_MOUSE
Sequence: MAFVFYCFLQVLVSWVIHAVQPFCLPECTCSEESFGRSLQCMSMSLGKIPDNFPEELKQVRIENSPLFELSQGFFTNMSSLEYLWLNFNNVTVIHLGALEDLPELRELRLEGNKLRSVPWTAFRATPLLRVLDLKHNRIDSVPELALQFLTNLIYLDISSNRLTVVSKGVFLNWPAYQKRQQLGCGAEFLSNMVLSLHNNPWLCDCRLRGLAQFVKSVGPPFILVNSYLVCQGPVSKAGQLLHETELGVCMKPTISTPSVNVTIQVGKNVTLQCFAQASPSPTIAWKYPLSTWREFDVLASPIAEGIILSQLVIPAAQLVDGGNYTCMAFNSIGRSSLVILLYVQPAQAMPGLHFLSTSSEVSAYVDLRVVKQTVHGILLQWLTVTNLAEEQWFTLYITSDEALRKKVVHIGPGINTYAVDDLLPATKYKACLSLRNQPPSQGQCVVFVTGKDSGGLEGREHLLHVTVVLCAVLLALPVGAYVWVSQGPYNFSEWCWRRCPLHRKTLRCPQAVPQCKDNSFKDPSGVYEDGESHRVMEEDEEVEKEGIS
What are the official names of this protein?
Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 2, Leucine-rich repeat-containing protein 22.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: GACJ_DICDI
Sequence: MEEQQPPSIKKKIVDFLTNFLKKRPSHEDLRRDNILVAPNNVSPAIQPSRYELEGHLNPSSHNRDDSSNNNNNNNNNNNTVEYSRGHSKSHSRSDSKHHNRENSKSDRDNSRSDNIRFGRKDTFKNAWDYLRNIDFTFSKTKYGNTVVHRLKHPQFGLSPEELQSLYPDQPHGIPIVLTKCFEYLSKHLETEGLFRVPGSNREVSLLKFKIEDGDLDFSEVLIPYNICGLISTFFKELPEPLIPFDYYNDAILITKLGSKDKYIIGLRDLVLSLPPANLCMLRKLLEFLLTVEKKNEFNKMTISNISIIFGVTLLKDPDTVDPMKSLNNIQAQSTIIKYMLEYFNDIFKEASVVKAYRKSIVPKEPMDTTSISYLDPAESNGGSPRTSNTPYQQQHQLSSQSMANIKPRPPSRSKMMRETIVLSPRVSGGNNQVYANATMTRPMSRLFFDPEIIPSPPPTTTTTTTTTTNTTTTTTTTNTTPNNTTTVNIQQKPVPPKPNLIPRKLPPNPNYSTYPAPLPPRQPNTIPLAPIPPPKPNSTYKKQITQPPPPRKPTSPSPPIATLKPTSKSDFIPSTNNNLNNNNTTTTTSSLISIPKAKPPPPKRNNVVSPAIEEPINPNLNINSTTTTPTPPLASFKNNGTISSGSKSNPNLQNLLNTNQPLVSSNGPPNKPPPQPFELLKSKPITTTPTIKKGVTFSETPKISNSPPSPSSSSPSPPHNQPIIVNKPIPSKSAPPPVRTTSSPSIVTKKFVPTIPTQTTTASSSSTPTTPKNQHLSKDDSSIPPINTSQTNNNISNSSIPSPKSKSALSLSTPKDSITGKPIKPPSNSDLSISTTPLPPTSSSPTSSSPLQSPKISSPSVLTVSQKIALNEKIAANQAKKNPLSNSGGLKQISPDLIKSNNINK
What is the function of this protein?
Rho GTPase-activating protein involved in the signal transduction pathway.
What are the official names of this protein?
Rho GTPase-activating protein gacJ, GTPase activating factor for raC protein J.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AES_SALEP
Sequence: MKPENKIPVLTRLSDEMKAVVNFQQPGLPPWPADGDIETQRQYYLLERRFWNADAPSMTTRTCAVPTPYGDVTTRLYSPQPTSQATLYYLHGGGFILGNLDTHDRIMRLLARYTGCTVIGIDYSLSPQARYPQAIEETVAVCSYFSQHADEYSLNVEKIGFAGDSAGAMLALASALWLRDKHIRCGNVIAILLWYGLYGLQDSVSRRLFGGAWDGLTREDLDMYEKAYLRNDEDRESPWYCLFNNDLTRDVPPCFIASAEFDPLIDDSRLLHKTLQAHQQPCEYKMYPGTLHAFLHYSRMMTIADDALQDGARFFMARMKTPR
What is the function of this protein?
Displays esterase activity towards short chain fatty esters (acyl chain length of up to 8 carbons).  Able to hydrolyze triacetylglycerol (triacetin) and tributyrylglycerol (tributyrin), but not trioleylglycerol (triolein) or cholesterol oleate.  Negatively regulates MalT activity by antagonizing maltotriose binding.  Inhibits MelA galactosidase activity.
What are the official names of this protein?
Acetyl esterase.
What is the protein family that this protein belongs to?
Belongs to the 'GDXG' lipolytic enzyme family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASSY_PROM4
Sequence: MEVKKVVLAYSGGVDTSSCIPYLINEYGVEEVVAFAADLGQGDELEPIREKALSAGASECLVDDLVKPFIEDFAFPAIRANALYEGKYPLSTALARPLISKRLVDIAKELEADAVAHGCTGKGNDQVRFDIAIATLAPELKVLTPARQWGMSREEVIAYGERYGIPAPVSKKSPYSIDLNLLGRSVEAGPLEDISLSPPEEVYQITSSIENTPDQSQEIEIIFEGGNPIAIDGVELDPLSLIVLANQLAGKHGFGRIDMIENRVVGIKSREIYETPGLLLLIKAHQELESLTLPADVLRTKSTLETQWADLVYQGLWFSPLKNALDGFIDRTQDEVNGSVKVKLHKGNATITGRSSSQNSLYLPDFSTYGSQDKFKHDNAEGFIYIWGLPSRLWAQSKNK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_STRSY
Sequence: MRYLTAGESHGPRLTAIIEGVPAGLPLTAEDINEELKRRQGGYGRGSRMQIETDRVEITAGVRHGKTTGAPITLNVTNKDHQKWLDIMAVEDIEEKLKSKRRIKHPRPGHADLVGGMKYRFDDLRNSLERSSARETTMRVAVGAVAKRILAELDIEIANHVVVFGGKEIDVPDGLSVAEIKERAAQSEVSIVNQEREEEIKAYIDQIKRDGDTIGGVIETVVGGVPAGLGSYVQWDKKLDAKLAQAVVSINAFKGVEFGVGFQAGYLKGSQVMDEILWSQEKGYTRRTNNLGGFEGGMTNGEALIIRGVMKPIPTLYKPLMSVDIDTHEPYKATVERSDPTALPAAGVVMESVVATTLATEILEKFSSDNMEELKAAVASHRDYVKNF
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: LPXH_YERPA
Sequence: MSTLFIADLHLSVQEPAITAGFLHFIQREAIHADALYILGDLFESWIGDDDPEPLYRQVAAALKSLQQQGVPCYFIHGNRDFLLGKRFAEESGMVLLPEENVVELYGRKILILHGDTLCTDDTDYQHFRKKVHNPLIQKLFLWIPLRLRLRIAAYMRNKSQQNNSGKSERIMDVNSKAVIDAFLRHDVSWMIHGHTHRPAIHSVELPMVTAHRVVLGAWHVEGSMVKVTADNVELITFPF
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: LPRG_MYCTA
Sequence: MRTPRRHCRRIAVLAAVSIAATVVAGCSSGSKPSGGPLPDAKPLVEEATAQTKALKSAHMVLTVNGKIPGLSLKTLSGDLTTNPTAATGNVKLTLGGSDIDADFVVFDGILYATLTPNQWSDFGPAADIYDPAQVLNPDTGLANVLANFADAKAEGRDTINGQNTIRISGKVSAQAVNQIAPPFNATQPVPATVWIQETGDHQLAQAQLDRGSGNSVQMTLSKWGEKVQVTKPPVS
What is the function of this protein?
Constitutes a host TLR2 agonist (toll-like receptor).
What are the official names of this protein?
Lipoarabinomannan carrier protein LprG, 27 kDa lipoprotein, Antigen P27, Lipoprotein LprG, Triacylglyceride transfer protein LprG.
What is the protein family that this protein belongs to?
Belongs to the LppX/LprAFG lipoprotein family.
What are the subcellular locations of this protein?
Cell inner membrane; Lipid-anchor. Secreted, cell wall. Secreted.
Protein: DAPF_SALNS
Sequence: MQFSKMHGLGNDFMVVDAVTQNVFFSPELIRRLSDRHLGVGFDQLLVVEPPYDPELDFHYRIFNADGSEVSQCGNGARCFARFVRLKGLTNKRDIRVSTANGRMVLSVTEDELVRVNMGEPNFEPAQVPFRANKAEKTYIMRAAEQTILCGVVSMGNPHCVIQVDNVDTAAVETLGPVLESHERFPERANIGFMQVVRREHIRLRVYERGAGETRACGSGACAAVAVGIQQGLLAEEVRVELPGGRLDIAWKGPGHPLYMTGPAAHIYDGFIHL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM175_RAT
Sequence: MSRLQVQEQAVDSEGDSSLYRRDEEGTQSSHRMLGFSDALLSIIATVMILPVTHTEISPEQQFDKSIQKLLATRIAVYLMTFLIVTVAWAAHTRLFQVVGKIDDTLALLNLACMMTITLLPYTFSLMVTFPDVPLGIFLFCMCVIAIGSVQAMIVGYAFHFPHLLNPQIQCSTHRALSRRHILHLVLRGPALCFVAAVFSLFFFPLSYLLMVTVIFLPHISKATTWCKDKFMGHRESPAHNVEPFSIDLHAPLSKERVEAFSDGVYAIVATLLILDICEDNVPDPKDVQQKFSGSLVAALGAYGPQFLAYFGSFATVGLLWFAHHSLFLHVRKATQTMGLFNILSLAFVGGLPLAYQQTSAFARQPRDELERVRVSCAIIFFASIFQFAIWTTALLHQRETLQPAVQFGGQEHAFMFAKLALYPCASLLAFAATCLLSRFSTAIFHLMQIAVPFAFLLLRLLVRLALAGLQVLWDLWPERPQQDQGEPETQSQLLPASC
What is the function of this protein?
Proton-activated proton channel that catalyzes proton efflux from endosomes and lysosomes to maintain a steady-state pH (By similarity).  Activated at low pH (under pH 4. 6) by luminal side protons: selectively mediates lysosomal proton release from lysosomes, eliciting a proton leak that balances V-ATPase activity to maintain pH homeostasis (By similarity).  Regulation of lumenal pH stability is required for autophagosome-lysosome fusion (By similarity).  May also act as a potassium channel at higher pH, regulating potassium conductance in endosomes and lysosomes (By similarity).  The potassium channel activity is however unclear as it was tested in non-physiological conditions for a lysosomal channel (By similarity).  Constitutes the pore-forming subunit of the lysoK(GF) complex, a complex activated by extracellular growth factors (By similarity).  The lysoK(GF) complex is composed of TMEM175 and AKT (AKT1, AKT2 or AKT3), a major target of growth factor receptors: in the complex, TMEM175 channel is opened by conformational changes by AKT, leading to its activation (By similarity).  The lysoK(GF) complex is required to protect neurons against stress-induced damage (PubMed:32799888) (Probable).
What are the official names of this protein?
Endosomal/lysosomal proton channel TMEM175, Transmembrane protein 175.
What is the protein family that this protein belongs to?
Belongs to the TMEM175 family.
What are the subcellular locations of this protein?
Endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein.
Protein: RIMM_POLNA
Sequence: MRPGLQPSLGLTSSSLPDDALEVGRILDAWGVKGWVKILPHSTDPEALFSAKTWYLQTPDVKFRPGFSLFSGTVSLKVDEAKIHSGAVVAKFSGLDDRDAAEALRGARIFLSRSSFPAASADEYYWVDLIGLNVLNREGVALGCVRDLMATGPHSVLCVEYASTQEDGTSATAERMIPFVAAYVDKVDIAGKCITVDWQPDY
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMTB_CHLAA
Sequence: MDGTTTTLPLAGIRVIDAATVIAAPFCATLLGEFGADVLKVEHPIGGDALRRFGTPTARGDTLTWLSESRNKRSVTLNLQHPEGARVFKELIAHSDVLCENFRPGTLEKWGLGWDVLSKINPRLIMLRVTGYGQTGPYRDRPGFARIAHAVGGIAYLAGMPKGTPVTPGSTTLADYMTGLYGCIGVLLALRHREQTGRGQYIDAALYESVFRCSDELVPAYGMYRKVRERHGSHYNEFACPHGHFQTKDGKWVAISCATDKLFARLANAMGRPELASSSVYGDQKVRLAHASDVNEIVRDWCSSLTRAEVLERCYATATPAAPLNDIADFFGDRHVHARRNLVAIDAEDLGETLIMPNVVPKLSETPGSIRSLGPKLGEHTEEVLKEILGMCDEQINDLRSKRVI
What is the function of this protein?
Involved in the 3-hydroxypropionate cycle used for autotrophic carbon dioxide fixation.  Catalyzes the transfer of CoA moiety from succinyl-CoA to L-malate to yield L-malyl-CoA (By similarity).
What are the official names of this protein?
Succinyl-CoA--L-malate CoA-transferase beta subunit.
What is the protein family that this protein belongs to?
Belongs to the CoA-transferase III family.
Protein: HGPRT_STRT2
Sequence: MLEKDIKKILFSQEDIVTKTKELGQQLTKDYAGKNPLLVCVLKGAVPFMAELIKHIDTHIEMDFMVVSSYGGGTVSSGEVKILKDVDTNIEGRDVIFIEDIIDTGRTLLYLRDMFKYRKASSVKIATLFDKPEGRVVDIEADYVCYDVPNEFIVGFGLDYDEKYRNLPYVGVLKEEIYNK
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.
What are the official names of this protein?
Hypoxanthine-guanine phosphoribosyltransferase, HGPRT, HGPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KUP_METBF
Sequence: MFSKSEFREVVKSMGLVFGDIGTSPIYTLTVIFLLTRPTHTHIIGVLSLIIWTLIILVTVEYAWLAMSLGKKGEGGTIVLKEILVPLLKSSRNVAFVTLLAYIGTSFLMGDGVITPAISILSAVEGLRIIPQFENIGQSTIILISAAIAIALFSVQSKGIEKITWVFGPIMVLWFATIGFSGIASIFYTPEVLKAINPYYAIRFLLDNGIIGFFVLSEVILCATGGEALYADMGHLGREPILKAWRFVFLALVLNYLGQGAFLIRNPGSTNFLFEMINQQANILYIPFLLLSVVATIIASQAMISGMFSIVYQGITTRIIPMLKIDYTSGVFKSQIYISTVNWLLLVSVLFMMLIFKESSKLAAAYGLAVTGTMSITGIMMTSIFYHRKNITKALISLFITFIDVVFLLSNSYKIPHGGYWSVIIALFILSLILIYTSGQKKLYKLMKLMKSKDFLEKYKQVYATQNKIMGTALFFTRDIERIPQYISHVMFKNNIIYENNIFISIIKSDSPFGIETSFTKEPAKGLKILEIRAGYMEIVNVEKILKDQGIGEKTIFYGVEDIFTKNIIWRIFSIIKKVSPSFVQFYKLPTDELHGVMTRFEM
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SIM29_MOUSE
Sequence: MSNTTVPNAPQANSDSMVGYVLGPFFLITLVGVVVAVVMYVQKKKRVDRLRHHLLPMYSYDPAEELQEAEQELLSDVGDPKVVHGWQSSYQHKRMPLLDIKT
What are the official names of this protein?
Small integral membrane protein 29.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: LTV1_SCHPO
Sequence: MGKKKFVNKNKAQTFHLVHRSQRDPQYHDENATERVLVSAETLNKTARRLNRQTLDEEYGSTIRPNEGEAANYGIYFDDTEYDYMQHLRNIGNEDATWVEAPATRKTQDKQKKQQIQLRDQPSILPQEVLPSEVELERTYQDQQSVPDAISGFQPDMDPRLREVLEQLEHSDINDEETSDFDEEFEKLVASGKADESEFYAQPFVEEGEKDYDEAAAAKAGKSEWEIEFEKFKLEQKKQPDVASSDGDFSDEPESEERDEVPELVSSSKSKSKTKRKARTALSSVSMSSSALFRNEGLTLLDDRFDKVEEEYTPIKDERELIDPDQKDVFDLVNDNQFNDIMDEFLVSYGPTLGRKKAPSRMSNSKKKSSLEELDNVRKMLGRARI
What is the function of this protein?
Involved in protein transport.  Non-ribosomal factor required for efficient nuclear export of the ribosomal 40S subunit.  May participate in intracellular sorting of GAP1 out of the endosome (By similarity).
What are the official names of this protein?
Protein LTV1.
What is the protein family that this protein belongs to?
Belongs to the LTV1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm.
Protein: SP5S_BACSU
Sequence: MEILKVSAKSSPNSVAGALAGVLRERGAAEIQAIGAGALNQAVKAVAIARGFVAPSGVDLICIPAFTDIQIDGEERTAIKLIVEPR
What is the function of this protein?
Induced early in sporulation under the control of sigma-H.  Interferes with sporulation at an early stage.  Seems to play a positive role in allowing cells to progress beyond stage V of sporulation.
What are the official names of this protein?
Stage V sporulation protein S.
Protein: AROE_CROS5
Sequence: MSIITGKTKLLGIIGHPVEHSLSPVMQNAEIKRLGVDYIYIPFPVKPENLETALDGFATIGVMGFNATIPHKQAIIPLLSEVTTTAKLVGAVNTVWRTEIGWKGTNTDVIGFVTPLKALNRDWNTIKPIILGNGGAARAVVVGLAELGCRDICVVGRDKDKLGQFKQSWDTSELQASITVHSWDELSGMVSESQLIVNTTPIGMFPHTQNSPVDSNLWEKLPNNAIAYDLIYNPSPTQFLKDAKQQGLTVIDGLDMLVYQGAAALEIWLQQPVSATVMSEALKQSLFS
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: GLMM_RHIWR
Sequence: MGRRYFGTDGIRGRTNESPMTAEIAMKVGQAAGAHFVRGEHRHRVVIGKDTRLSGYMMESALVAGFTSVGMDCVLLGPMPTPAVAMLTRSMRADLGVMISASHNMFADNGIKLFGPDGYKLSDDDETAIEARLEKPVKLAASADIGRAHRVESARGRYVHAVKSSFPEHLRLDGLRVVIDCAHGAAYEVAPLALWELGAELISMGVNPNGVNINDQCGSTDTRALQDKVRETRADIGIALDGDADRLIIVDNEGRVVDGDQLMALVAVGAHRRGELRGGGIVATVMSNLGLERFLAEQGLSLHRTKVGDRYVVEAMRAEGFNIGGEQSGHIVMTDHATTGDGLVAALQVLAQLVESGKPASELLHQFDPLPQLLKNVRFAGGEPLKDEKVIAAIADAEEKLTGTGRLVIRKSGTEPLIRVMAEGEDKRLVEAMVDQICDAVRKAA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: ELMOA_DICDI
Sequence: MKIKVTFQERIIEHNFETEITNLQQVTQKLCSLFLITNYYSYSLFLSSGQLVDNINLIDEGSEIIIKHLNRLGTISIGSGYSNSVVGTTNNNAPSSPSSSININGQQIQQQIQQQIQQQQQQQQQQQQQVQLSPDTLINNLLNNLKDNTFKKKAFFDLKDLKEEILIKKFVEKNGIEVIVCQLKELTGNTLSYALSALQTIMSYEFTITSMTSTDTASLITQLLPLTENTSNPSISKTSLSLLCLFLNQSNNLNFKQFSSTLVLEYNEKTKRNYNHTLVQLLSSSNTVDVQLNALTLINIIIGKTMSTTIPGLENGSVTGGENGFNKLLKELDEYEINQKLKKLVESIIVAPELKRQLYIYQRHRFQVITNRKNVTFNKESSEHDALLMKLWSLTYPGVKLESRVSEQWKQMGFQGTDPCTDFRAMGIWGLDNLIYFAQNYNEKFRKIVNSQIDRKEREYPTATAGIVLTFELYNSIFKMGTPNLNPYNSTTSNTTSNTTSTTNIDDLPFFPLFFSHPHAFEEVYCTTFQILDSTWDDMNGTYMHFQKIMSSVKNLIITALESKPTTLEAFDWKCQKNTKNSNGGTNSNQNNSSSNLLLSNFANGSSLLSLLNDLSSSSRDDMKKLLTGVNYQVLDLIKSQKISYFQEGFQFKLHKQLKTKQSLPLNWIFIRLFNNNNNNNNNNENCSYEIQYCFLSTELNQPPLPNQSIPTNYNTIKISDLFFNGESTNSNNKKKDKSLSYFNISIKDEQIQSLIQNQLPLSNLNNSSNSLQLDSSTSMNSIKDSIINISSSNNNIKDNLTNNNTNTNTNNTNNNTSNGNGNSNSVSMSSININNSGQLSPNTTSPILIPQQQQQQPQSSSLSVQHQQSSTPTPSSPVLLSSPSLQSSSSSSSSSSNPNLFTIDLISSNRDDVSNFWDSIKLLSGQEIKSQEGLDDYHSLLSINTSVKLLDLDGIDIPKETPQIPILPDNFDFRTV
What is the function of this protein?
Functions as a negative regulator of actin polymerization.  Modulates actin/myosin II at cortex actinomyosins to prevent excessive F-actin polymerization around the cell periphery, thereby maintaining proper cell shape during phagocytosis and chemotaxis.
What are the official names of this protein?
ELMO domain-containing protein A.