PharMolix/UniProtQA huggingface dataset:
Protein: RL7_HERA2
Sequence: MASEKVTALLEELKGLTLVEAAELAKEMEEVFGVSAAAPVMVAGVAAAGDAPAAAAEEQTEFTVILKGAPADKKIAIIKAVREVVAGLGLKEAKDLVEGAPKPVKEGVSKEEAEAAKAALAAAGAEIEIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: UNG_CLOPS
Sequence: MAAEFNNDWDDLLKDEFEKEYYLNLRKFLIDEYKTQKIHPSMYDIFNALKFTPYKDVKVVILGQDPYHGPNQAHGFSFSVKPGVQTPPSLRNMFKELNSDLGCYIPNNGFLESWAKQGILLLNTVLTVREGQANSHKGKGWEIFTDRVIELLNKREEPIVFILWGRNAISKETLITNPIHKIIKSVHPSPLSATRGFFGSKPFSKTNDFLVSINKEPIDWQIPNI
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EF1A_METM7
Sequence: MAKEKPILNVAFIGHVDAGKSTTVGRLLLDGGAIDPQLIVRLRKEAEEKGKAGFEFAYVMDGLKEERERGVTIDVAHKKFPTAKYEVTIVDCPGHRDFIKNMITGASQADAAILVVNVDDAKSGIQPQTREHVFLSRTLGISQLAVAINKMDTVNFSEADYNEMKKMLGDQLLKMVGFNPDNITFVPVASLHGDNVFKKSDKTPWYNGPTLAEVIDAFQPPEKPTTLPLRLPIQDVYSITGVGTVPVGRVETGIIRPGDKVIFEPAGAVGEIKTVEMHHEQLPSAEPGDNIGFNVRGVGKKDIKRGDVLGHTTNPPTVAADFTAQIVVLQHPSVMTVGYTPVFHAHTAQIACTFMELQKKLNPATGEVLEENPDFLKAGDAAIVKLMPTKPLVIESVKEIPQLGRFAIRDMGMTVAAGMAIQVTAKNK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha, EF-1-alpha, Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_TRIEI
Sequence: METAIESIQAREILDSRGRPTVEAEVHLVNGSMGLAQVPSGASTGSFEAHELRDGDKGRYSGKGVLTAVKNVEEQITPNLVKINALNQNLVDSKMIEIDGSPNKSNLGANAILAVSLATAKAAANSVGMPLYRYLGGPQASLLPVPLMNVINGGAHAANNVDIQEFMIVPVGATSFKEALRWGAEVFATLSGVLKDKGLLGGVGDEGGYAPNLGSNQEALDILIAAIEKAGYKPGEQVALALDVAASEFYKDGNYIYDGATHSPSELIDYLASLVDQYPIVSIEDGLHEEDWESWVQLTQKLGSKVQLVGDDLFVTNGSRLQKGIDMAAGNSILIKLNQIGSLSETLETIDLATRNSYRSVISHRSGETEDTTIADLAVGTRAGQIKTGSLCRSERVAKYNRLLRIEDELGDRAVYAGVIGLGPKSRS
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: CAF1C_ARATH
Sequence: MKQISSGEVWRWNKEVEMNSIRDCLKHCSSIAIDTEFPGCLKETPMDASEEIRYRDMKFNVDNTHLIQLGFTLFDRRGFAKTWEINLSDFDEHKCFKNDKSIAFLKSNGLNLDKIREEGIGIDEFFRDFSQILTEKDGKITWVNFQGSYDNAYLVKGLTGGKPLPETKEEFHETVQQLLGKFVFDVKKIAESCSGLSSQFGLQRIADVLQMKRVGKAHHAGSDSELTARVFTKLTFDLLNSRKQSVRRVDHQQFQLEQQQHQQFMMTRCYIPIPMPIPRPRPVMFAAHHQNPYFGGGYFRMPVQGMNYVL
What is the function of this protein?
Ubiquitous transcription factor required for a diverse set of processes.  It is a component of the CCR4 complex involved in the control of gene expression (By similarity).
What are the official names of this protein?
Putative CCR4-associated factor 1 homolog 3.
What is the protein family that this protein belongs to?
Belongs to the CAF1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: GLGB_CERS1
Sequence: MNVTSKPGELVPESDVAAIMRGTHGDPFRVLGMHGGGGAPLSVRVFAPQAAEVAVLGQGGKVLASLERIGAEGFFAGTVPGEEKFPYRLRFVSGPHEWEADDPYRFPEVLGELDEYLLGEGRHYQLYTRLGAHPAEIEGVQGVSFAVWAPNARRVSVVGAFNAWDGRRHPMRKRIGVGVWELFVPGLHTGDLYKYEILGPSGERLPLKSDPLSFAQEAPPATASVVHGLPEAEWHDAGWMQERESRQRRDAPISIYEVHAGSWRQGLDYDALAEELSAYVREMGFTHVEFLPISEHPFTGSWGYQPIGLFAPTARFGPPEGFARLVDRLHRDGIGVILDWVPAHFPSDAHGLANFDGTHLYDHADPRQGFHRDWNTQIYNFGRQEVANFLQASALFWLDRYHVDALRVDAVASMLYLDYSRNAGEWVPNRHGGRENLEAIDFLRGVNERVRLDHPGCITIAEESTAFPQVSRPVEDGGLGFGFKWNMGWMHDTLGYFRRDPIHRKHHQNDLTFGMVYAYSEDFVLPLSHDEVVHGKGSLIGQMAGDRWQKFANLRAYFGFMWAHPGKKLLFMGGEFAQEREWNHDASLDWHLLDDPSHAGMKRLVADLNREYRKRPALHRMDCDPEGFEWIDAGDSENSVLSFLRKAPGEKPVLAVCNLTPVVRSDYRIGVPEGGEWREILNSDAAIYGGSDVGNPGGLQAEEVSWHGRPASLRLTLPPLATIFVTPA
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: RF1_DICTD
Sequence: MLQKLVIDKLEEIEKRFEEIEGLLAKEDVISDFNKYQSLLKERAKIEEIVDKFREYKRLLKEKEDLEEMVKEEQDEDLRSLAETELEDIQEKLEKVEFELKALLLPKDPNDEKNIIMEIRAGTGGEEAALFAADLFRMYLGYAQKKGWKVEIVSSNPTGLGGFKEIIFIVEGKGAYSRLKFESGVHRVQRVPITESSGRIHTSTATVAVLPEMEEIEVEIDPKDLRIETFRSGGAGGQHVNKTESGVRITHIPSGIVVQCQDERSQHQNREKAMKVLRARLYEYYQREKENEIASQRRQQVGTGERSEKIRTYNFPQRRVTDHRINYSSFQLEEVLSGELDEFIDRLILAEKEEQIKKLFEEVGATS
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IL33_MOUSE
Sequence: MRPRMKYSNSKISPAKFSSTAGEALVPPCKIRRSQQKTKEFCHVYCMRLRSGLTIRKETSYFRKEPTKRYSLKSGTKHEENFSAYPRDSRKRSLLGSIQAFAASVDTLSIQGTSLLTQSPASLSTYNDQSVSFVLENGCYVINVDDSGKDQEQDQVLLRYYESPCPASQSGDGVDGKKLMVNMSPIKDTDIWLHANDKDYSVELQRGDVSPPEQAFFVLHKKSSDFVSFECKNLPGTYIGVKDNQLALVEEKDESCNNIMFKLSKI
What is the function of this protein?
In quiescent endothelia the uncleaved form is constitutively and abundantly expressed, and acts as a chromatin-associated nuclear factor with transcriptional repressor properties, it may sequester nuclear NF-kappaB/RELA, lowering expression of its targets.  This form is rapidely lost upon angiogenic or pro-inflammatory activation.
What are the official names of this protein?
Interleukin-33, IL-33.
What is the protein family that this protein belongs to?
Belongs to the IL-1 family. Highly divergent.
What are the subcellular locations of this protein?
Nucleus. Note=(Microbial infection) Upon infection with H.polygyrus, tethered to the nucleus by the H.polygyrus parasitic protein ARI. SUBCELLULAR LOCATION: Nucleus. Chromosome. Cytoplasm. Cytoplasmic vesicle, secretory vesicle. Secreted. Note=Associates with heterochromatin and mitotic chromosomes. The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion.
Protein: G6PI1_NEIMA
Sequence: MKHLHDLPAWSKLWNHFDDSKTLHMREMFEQDPQRAERYWLQVGGLTLDYSKNRINDETMSLLFELAHEAGVPERMRQMFHGKKINTTENRAVLHVALRNRTNSPIVVDGEDVMPKVNRVLQRMGEFAHEVRSGSWLGYTNQVITDVVNIGIGGSDLGPLMMCTALKPFGHPRLNMHFVSNVDGSQLRDVLSKVHPETTLFIIASKTFTTQETLTNALTAREWFLNHAGDEEAVAKHFAAVSTNQKAVAEFGIDTANMFEFWDWVGGRYSLWSAIGLPIMLYLGEENFIEMLNGAHLMDQHFINTPLERNLPVILALIGIWYINYYGGGSHVIAPYDQHLHRLPKFIQQLDMESNGKQVTLDGKAVGHETSPIIWGETGINGQHAFFQLLHQGTHITPIDLIASLEKRSNLPGHHEILLANVFAQAEAFMRGKTPDEVRAELKAQGMDEARIEELVPHKTFSGNRPTNLILMDKVNPRNMGSLIAMYEHKTFVQGIIWGINSFDQWGVELGKQLAKTILGELTGETGSQKHDSSTERLINLYLQTNRK
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase 1, GPI 1, Phosphoglucose isomerase 1, PGI 1, Phosphohexose isomerase 1, PHI 1.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIE_METMP
Sequence: MKFKDKLKFYVITDSNYSDEVISVEESLKGGATSIQLRMKTSSTRKMIEVGNKLRKLTSEYDALFFVNDRLDVAQAVNADGIHVGIDDMPVSKIKEIAPNLIIGASAYNLDEMKTAESEGADYLGVGAVYSTNTKLDARDLGINGLKNISKIANLPIVAIGGINHSNVENVLKCGVSGVAVVSAIVGAENILKSAENMNELIKKYIK
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: FLC_ARATH
Sequence: MGRKKLEIKRIENKSSRQVTFSKRRNGLIEKARQLSVLCDASVALLVVSASGKLYSFSSGDNLVKILDRYGKQHADDLKALDHQSKALNYGSHYELLELVDSKLVGSNVKNVSIDALVQLEEHLETALSVTRAKKTELMLKLVENLKEKEKMLKEENQVLASQMENNHHVGAEAEMEMSPAGQISDNLPVTLPLLN
What is the function of this protein?
Putative transcription factor that seems to play a central role in the regulation of flowering time in the late-flowering phenotype by interacting with 'FRIGIDA', the autonomous and the vernalization flowering pathways.  Inhibits flowering by repressing 'SUPPRESSOR OF OVEREXPRESSION OF CONSTANS 1'.  At elevated temperatures (e. g.  29 degrees Celsius), maintained at high levels in a JMJ30/JMJ32-dependent manner to prevent extreme precocious flowering (PubMed:25267112).
What are the official names of this protein?
MADS-box protein FLOWERING LOCUS C, MADS-box protein FLOWERING LOCUS F.
What are the subcellular locations of this protein?
Nucleus.
Protein: PPM1A_HUMAN
Sequence: MGAFLDKPKMEKHNAQGQGNGLRYGLSSMQGWRVEMEDAHTAVIGLPSGLESWSFFAVYDGHAGSQVAKYCCEHLLDHITNNQDFKGSAGAPSVENVKNGIRTGFLEIDEHMRVMSEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHKPSNPLEKERIQNAGGSVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQLVSPEPEVHDIERSEEDDQFIILACDGIWDVMGNEELCDFVRSRLEVTDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAPKVSPEAVKKEAELDKYLECRVEEIIKKQGEGVPDLVHVMRTLASENIPSLPPGGELASKRNVIEAVYNRLNPYKNDDTDSTSTDDMW
What is the function of this protein?
Enzyme with a broad specificity.  Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling.  Dephosphorylates PRKAA1 and PRKAA2.  Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB.
What are the official names of this protein?
Protein phosphatase 1A, Protein phosphatase 2C isoform alpha, PP2C-alpha, Protein phosphatase IA.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol. Membrane; Lipid- anchor. Note=Weakly associates at the membrane and N-myristoylation mediates the membrane localization.
Protein: Y123_ARCFU
Sequence: MNVEVGEECIRFAKVIRYFTLAGLILLVVSSAMYLLDIDPFVEPDRVVETWHLPASEFWKVNVGKEMESYSEFLYIAHPDNVAVFSLFFLALAPVFALLSILPKMKGIYRILTILVVAELLFGAVRPLILGAIGE
What are the official names of this protein?
Uncharacterized protein AF_0123.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FACE2_BOVIN
Sequence: MAALGGDGFRLLSVSRPERQPESAALGGPGPGLCCWVSVFSCLSLACSYVGSLYVWKSELPRDHPAVIKRRFTSVLVVSSLSPLCVLLWRELTGIQPGTSLLTLMGFRLEGIFPAALLPLLLTMILFLGPLMQLSMDCPCDLADGLKVVLAPRSWARCLTDMRWLRNQVIAPLTEELVFRACMLPMLAPCTGLGPAVFTCPLFFGVAHFHHIFEQLRFRQSSVGSIFLSAGHLIGPVLCHSFCNYMGFPAVCAALEHPQRRPLLAGYALGVGLFLLLLQPLTDPKLYGSLPLCVLLERAGDSEAPLCS
What is the function of this protein?
Proteolytically removes the C-terminal three residues of farnesylated and geranylated proteins.  Seems to be able to process K-Ras, N-Ras, H-Ras, RAP1B and G-gamma-1 (By similarity).
What are the official names of this protein?
CAAX prenyl protease 2, Farnesylated proteins-converting enzyme 2, FACE-2, Prenyl protein-specific endoprotease 2, RCE1 homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase U48 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: B2MG_CYPCA
Sequence: MRAIITFALFCVLYVTVQGKTSSPKVQVYSHFPGEYGKENTLICHVSGFHPPDITIELLKDGEILPNTQQTDLAFEKGWQFHLTKSVTFKPERGQNYACSVRHMNNKNIYSWEPNM
What is the function of this protein?
Component of the class I major histocompatibility complex (MHC).  Involved in the presentation of peptide antigens to the immune system (By similarity).
What are the official names of this protein?
Beta-2-microglobulin.
What is the protein family that this protein belongs to?
Belongs to the beta-2-microglobulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: IPI1_MAGO7
Sequence: MGSSVRKKKEKKKDFQKTKLKVGKAKEKPASFTDTSFKSRAIVVAQSSLTVEGPNPVEQFKHYLSLASTSRSENQRRDALAFLTTQLSHQPPNNPVGTPAILAKLLPLISDSNSGVRTQLYKLLQAFPSADIQPQVERISMYVRAGMTHLSADIRDDTLSIMEWLLEVAGSEVVSCAGGWMKTLNVFAAMLGWSSIVAANAAAAAGSAPRNKGWTSAPKSTFGAAKGGASYARQLLALAKFLEIGFRPEATGSGGQRTLWNSLYRLPRTSNPFGYLNLFGAPRDEDSEIYADREDRQRVFSRKWHAVITKGLEEAKKEGGAVGRAGAVLNQTLKDGLADYDDHVL
What is the function of this protein?
Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
What are the official names of this protein?
Pre-rRNA-processing protein IPI1.
What is the protein family that this protein belongs to?
Belongs to the IPI1/TEX10 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LIAS_CULQU
Sequence: MKYFFSLPFPKVHTTCKHTAAATASQPLQKIRERLESGPGFQEFVQNPSYNREDWSAYEGKLKREKGEQDRLRLPPWLKTKIPMGKNFSRIKDQLRELKLATVCEEAKCPNIGECWGGGEHGTQTATIMLMGDTCTRGCRFCSVKTARAPPPLDPDEPKKTASAIASWGLDYIVLTSVDRDDLPDGGSNHIAETIREIKRQNPRIFVECLAPDFRGNLDCIRTVATSGLDVYAHNIETVESLTPFVRDRRAEYRQSLKCLASVKEINPNMVTKTSIMLGLGETDEQVEQTMKDLRAVGVDCLTLGQYMQPTKRHLKVIEYVTPEKFKHWETRGNELGFLYTASGPLVRSSYKAGEFFITSILKNRAAAAAEEATATKPSE
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, mitochondrial, Lipoate synthase, LS, Lip-syn, Lipoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: EFP_EXISA
Sequence: MVSVNDLKTGLTVKTSDGSIWQVIEFQHVKPGKGAAFVRTKMRNLRNGAIQETTFRGGEKIERAHIERKRMQYLYPMGDTYVFMDNESYEQLELTSAQVKSALPYLLENMEVSIADYEGEILGIELPTSVVLTIVEADPGVKGDTASNVKKNATVETGHVIQVPLFIEPGEKVTVDTRTGEFMGRYNG
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_BIFLD
Sequence: MATKIRLKRQGKKFYAFYRVVVVDSRKKRDGKVIEEIGTYNPNTQPSTIQIKSDRAQYWLGVGAQPSEPVFKLLNITGDWQKYKGLEGAEGTLKTVEAGPDAEARIAAVENQAQKLKAAKAEAAAKAKAEAEAAAAAEEAPAEEAAEEAPAED
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: RL4_PSYWF
Sequence: MNLKTVTGAAVELSDTAFGREFNEALVHQVVTAYLAGARQGTRAQKTRAEVSGGGKKPWRQKGTGRARAGSTRSPIWVGGGRAFAAKPQDWSQKVNRKMYRGAMQCILAELVRQDRLILVDSITVSAPKTKELISKLAELNAPRALIVTNEVDENLYLAARNIPHVNVLGTNEVDPVSLIAFDKVIMSVDAAKQFEEALA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: ATG2_KLUMD
Sequence: MTSWLPQNLQKRLLLYTIKQVSLFSNVDVSNLDVSIGSQSHFGFTDIDLNVCEINLPNIEVLSGRISKLNLQLAVAGNVEISGEGMVFVLKPADGFFDDDSSEQWASSLTKSVMDMTKSILDTELSEYQSKIYKDTNEDIKPPTALDSMMDKVLRVALSKLTINLKNVELQLIISPELMLKISISEVKMISADEKRIADVIGVSAVFSKPEQSVPSYGSSSSDKEDDNTSDSEDPLSTSITYSKLEATSIYLSAMESLVLDSLDGETYQFLNIDKIEVQFQGITSINDLKVHDLKIKINALDIHLENVSSILSHIMSLLNHVQLSNSEDKIRTQELKSYKRFQHEQNIEEDKTLTFVLLNSLKFHLRDNLFIMLTEISLNSSVSPYTSVSISDIQLVLDSKEYINRSDSSEPFLSLNKNSSTSEQKLHLNRDIKVEVDYSLMKQLILFANDYMCLYNQIIERPSTYADPSADPKFLLSSQNVCFLLNLGDLIMEFHFSPFFSNIPHTTFKIPKLSIFSVQNNEKSHIGELTDFEFHSRKSGCFNISGANSKFCASNVNTKTKATLENLEVSILESDMNKIIQCLSGVLGSLPELLLSSGETTSSKNMEKRSVRMMQSSAFLHNRTALSMFCVQINCMKIKISNISGKAFGDLMITARKSLIYQDKYSDLSISFTEFTAQRQYRSEKTDIIFDINHDSNIANFVINRTKVGKIKAYLTGVGIFIHTKWSELFSGQKTENSINEQKKNAKTLVSIPIDIKLYDCALSLKPCRLSTGLAINIPRAQINITKNEITLSTKILDLLLIDDMNLIHETDLGHTTSTSNWYEKQGYSSLVKIDTLSVRFCPGGVASTRVNVHKIDSSICSDSFNALIQTIIDLKPVVTYPENVKYQLEPELVSVFEDLTDQYFTTARISENDLEIYPDTYSNSGESLVFEENYFSPKLESPSKNEVNMAVFEILSNVKISVDEIKLKLYDGYDWKHTRKEINSAVEQLEENFKDGLSCPDAKVFDSIYIPAPRDEDENIKSNINMKIHNEETKEGKMKLRPTKKYKILIQGNGIKVNIQSGNDELRTTSTLPLSDNTYDILNETSVQINNLEIVDNLPTSTWNKFLTRTKLKTTNTLQQSPMFSLRFTMIRPTPHLYATELIFSVHVKPISLHVDQDALEFLTLFFQFKDPRFELIDDYPDIPYIQRFEINSVKILLDYKPKKVDYVGLRSGKTKEFMNFFILDQAKINLKHVILYGIDGFSRLETILTDIWTPDITKTQLPGILGALTPFKPFAGLSYGARALVSVPTEQYQQSGRLGTSLQKGGMVFLRTTGGEFVKLAVRLTSGTQTILESTEKLLGGQGSNGRNIKIKLVEGDEIVDAFIDESILRSTTLFDNTANDNNHLDVILPQGDTQKVISLYADQPKDFYSGLHDAYSSFGRNLNITFDSMKQAKNDIKTANGAQEAVSTVAKAAPLALIRPLIGVTEALSKTLQGLNNQYDQEEIAHIEEKYKSSN
What is the function of this protein?
Lipid transfer protein required for autophagosome completion and peroxisome degradation.  Tethers the edge of the isolation membrane (IM) to the endoplasmic reticulum (ER) and mediates direct lipid transfer from ER to IM for IM expansion.  ATG2 binds to the ER exit site (ERES), which is the membrane source for autophagosome formation, using basic residues in its N-terminal region (NR) and to the expanding edge of the IM through its C-terminal region.  The latter binding is assisted by an ATG18-PtdIns3P interaction.  ATG2 then extracts phospholipids from the membrane source using its NR and transfers them to ATG9 to the IM through its predicted beta-sheet-rich structure for membrane expansion.
What are the official names of this protein?
Autophagy-related protein 2.
What is the protein family that this protein belongs to?
Belongs to the ATG2 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: Y761_ARCFU
Sequence: MENIMDEKGQMILLFAFVVVIVVLTLSYVYAQNIIAGVESSRAMLAFPKEEIRNLEEIQKNFGGDSEVNSQIQTLCAKNGWVCYVGVDKVEFKNVEVDYCAGSDC
What are the official names of this protein?
Uncharacterized protein AF_0761.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RNFB_BUCAP
Sequence: MSITIILIFSILSFLLGIILSYVKYIFPIKKNSIIAEVDDLLPQSQCAQCGYSGCYPYAKAIVKNNENIDKCIPGGNNLKFKIAKVLNIKNIKYSLDNLNAKNEKNIHTTVLIDEKNCVGCSKCASFCPVDAIIGTPNFMHTVLQKFCTGCNICLLHCPTNCIKIIKE
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit B, Rnf electron transport complex subunit B.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: PUR5_DESVM
Sequence: MSEDRSKAYTDAGVDINAGNALVSRIKSIVARTHTNGVISDIGGFGGLFKPDLAGMDEPVLVSSTDGVGTKLKCAFQFGKHDTVGIDLVAMSVNDILVQGARPLFFLDYFATGKLDVDVAASVISGVAEGCRRASCALLGGETAEMPEMYAPGEYDLAGFCVGLVDNTRIVDGSSIRVGDSIIGIASTGLHSNGYSLARKVLAQSGLNGNDPLPGSDRTVAEVLLEPTAIYVDIVRSVMRDFAIKGMVHVTGGGFYDNIPRVLPATVEAHIDFGSWTVPPVFNWLLAQGNLTWPEMLQIFNCGIGYIMIVSPDVCDEVLGRVNAMHAQAWRIGSIGRRRDKAAEQVQVAF
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LAP1_TRIVH
Sequence: MKLLSVLALSATATSVLGASIPVDTRAEKFLIELAPGETRWVTEEEKWELKRKGQDFFDITDEEVGFTAAVTQPAIAYPTSIRHADAVNAMIATLSKENMQRDLTKLSSFHNRYYKADFGKQSATWLQEQVQAAINTAGASRYGAKVVSFRHNWAQHSIVATIPGRSPEIVVVGAHQDSINQRSPMTGRAPGADDNGSGSVTILEALRGVLQDQTIVQGKAANTIEFHWYAGEEAGLLGSQAIFANYKQTGKKVKGMLNQDMTGYIKGMVDKGLKVSFGIITDNVNANLTKFVRMIISKYCSIPTIDTRCGYACSDHASANRNGYPSAMVAESPIDLLDPHLHTDSDTIDYLDFDHMIEHAKLIVGFVTELAK
What is the function of this protein?
Extracellular aminopeptidase which contributes to pathogenicity.
What are the official names of this protein?
Probable leucine aminopeptidase 1, Leucyl aminopeptidase 1, LAP1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family. M28E subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SMG8_DROME
Sequence: MLDDYYTWTYPDIPENVAQELLQLNGSLVVVGIVGRSDCDQANKMVAFGMEPPSEHTPKDGQMQCYYKPGTSILLLHFESTYDAEIAGQMIDVCIEDVDTPFDIDSFFEGIRCRFVRMMLLALHVCHIVVYVETGQTFDPTLITVFQLAKFAREQHLMQFLPQMLRETPAARMSERTRLCTPRILFLFENFPSDEPKTRECVSTYEFQMEDCIYELLRHHNIVTNSSSNSLVALPNNKQFVFFNAHEELREDTLMKAVECLNETMYKPDLKEEEEDLEILALAPFDGFVKPFALPVDEKEWDNQQYKKDHTVWNFLERHVQDALMGCFEAGSFKQHAQQGTFQLLNSKEWHDCMATMHTLLVENTKDPNLETSNEEYKNFLKNFDESLNYEKKFWAHLCELGLKKGIAAYKNAAPENYGSATHRQLLAEATLAFEEEGRGPQAQAALAKLASICHKHWQDGRQQCEQLSLRSHPCTLPKKVPHEKHNSGVIHISSCNCGRTQGRREDPFNLRQANYEFYEHIAQMCNLCVKVKQYQFPIFEPSVSDYRAAAFEAAFPLLNNGKSGAPQDEDAEEDEAEEEEGQEQEQPTEEQLQNTASNCCSQPLSPTFGSDLNMSIAGFGASLKESQASSEQLLNSEQNTTSSGTSSADTDNELVVELQEPAKKEAREDAGPAHAVSTSTTEYLPGLVHTVSNFGLLPLFPSWSLACVGPSSIYSHNTGLQEHFQSGFLSGANFLLPWDVQLRLVHAPKQQYQQQHHGKKQQRWKKQGDRLSLKIFVGMEYECSRGHRFMMCAPDRVLRGGADIERETCSMVVHNNMPLYYPCPCRSQNNFLAQLMRIHVVTPKAPVNIIVDPKVCVGRYTFTMGSIVPPRLSQSAYWIIRLPYVYQGDDVLIAPPEQLDPGYPLTGGYLLPGMFGVVETDPTLDLNEPDKMGASAAGNFTRI
What is the function of this protein?
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.  Probable component of kinase complex containing nonC and recruited to stalled ribosomes (By similarity).
What are the official names of this protein?
Nonsense-mediated mRNA decay factor SMG8, Protein smg-8 homolog.
What is the protein family that this protein belongs to?
Belongs to the SMG8 family.