PharMolix/UniProtQA huggingface dataset:
Protein: RASP1_TOXGG
Sequence: MFVLDPAAICCCAVTCCCGVGSVCAYRKRQSIPHPSECALIGKMYRLCGCHDHDKFDVLIEIHEIHDLTQSGKFFVEVHAGRSEERTGVCSAKKGRVEIQERVNIHVRQADKTLTVRVKKQGLTSTEAIGDAVIGVKSELIDGAFPKRQSFFCQKDGKTACKIVLSFHRLDTGNVSLGDFQMSPLLHQALLIAQSEAEARGETLQVDILNMTEVERLRFLSKVLEGPLKQMSSIGGAWKNLYFRAAERRNGKWEWQYWSSKDDCMSGIKKRGAYSFMAISLVLPDKHDRHCFYIRYHDTGGVHDLFFKRVDRDRNLWSDGLFEFIEKLREYLEKHPEVAMSGRGGHSSRREKKKEGDVGGSRTPRKRDGKALTPRTGASDDAGDDGIRGRSPRGSDRRALSHRSFVDPAELAEKRRVLSPRETAADEMTRPRASVLKGRMIEGLMYDRSLQPGEKNEEASEADERPRERTEGVEYEREEEQPLLFTQ
What are the official names of this protein?
Rhoptry apical surface protein 1, TgRASP1.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, rhoptry membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes to the extremity of the neck of the rhoptry (PubMed:31492901). Localizes to pre-rhoptry compartments as well as mature rhoptries (PubMed:31492901).
Protein: TYPH_ALIFM
Sequence: MYLPQEIIRKKRDNKELTTEEINFFIQGVAKETVSEGQIAAFAMAVYFNEMTMPERIALTCAMRDSGMVIDWSHMNFDGPIVDKHSTGGVGDVTSLMLGPMVAACGGYVPMISGRGLGHTGGTLDKLESIAGYNITPSNDVFGKVTKEAGVAIIGQTGDLAPADKRVYATRDVTATVDNISLITASILSKKLAAGLDSLVMDVKVGSGAFMPTYEASEELAKSIVAVANGAGTKTTALLTDMNQVLASTAGNALEVREAIRFLTGEYRNPRLYEVTMALCAEMLVIANLAKDEQDARAKLQTVLDNGKAAECFGKMVFGLGGPSDIIENYDNHLESAQIIKPVFADTTGFVHAMDTRDLGMAVVGMGGGRRVASDTIDYAVGLSDMIRLGQTADNQQPLAMIHARNEEQWQQAANAVKAAIVISEKQPEATPEVYRKIRPEDV
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: ZUPT_DESOH
Sequence: MSSILIALGLTLFAGMATGIGSAIAFFAKKQNYRFLSVATGFSAGVMLYVAFVEILAKGATALARAYGEIPGAWINAAAFFGGILLIGVIDNLIPSAENPHEVPSETQMADFRDACTLSDTGAADCDDAGRKAKLLRMGLFTALAIGIHNFPEGLATFLAALSDPALGVAIALAIALHNIPEGISVSVPIFYATGNKTKAFAWSLVSGMAEPVGALLGYLGLLFFFGNPAGGMPPQIMGILFAGVAGIMVYISVDELLPTSRAYGRGHDSILGMVAGMAVMAASLLMMK
What is the function of this protein?
Mediates zinc uptake.  May also transport other divalent cations.
What are the official names of this protein?
Zinc transporter ZupT.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BIP_CRIGR
Sequence: MKFPMVAAALLLLCAVRAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGEEDTSEKDEL
What is the function of this protein?
Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (By similarity).  Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10/ERdj5, probably to facilitate the release of DNAJC10/ERdj5 from its substrate (By similarity).  Acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR) (PubMed:29198525).  In the unstressed endoplasmic reticulum, recruited by DNAJB9/ERdj4 to the luminal region of ERN1/IRE1, leading to disrupt the dimerization of ERN1/IRE1, thereby inactivating ERN1/IRE1 (PubMed:29198525).  Accumulation of misfolded protein in the endoplasmic reticulum causes release of HSPA5/BiP from ERN1/IRE1, allowing homodimerization and subsequent activation of ERN1/IRE1 (PubMed:29198525).  Plays an auxiliary role in post-translational transport of small presecretory proteins across endoplasmic reticulum (ER).  May function as an allosteric modulator for SEC61 channel-forming translocon complex, likely cooperating with SEC62 to enable the productive insertion of these precursors into SEC61 channel.  Appears to specifically regulate translocation of precursors having inhibitory residues in their mature region that weaken channel gating.  May also play a role in apoptosis and cell proliferation (By similarity).
What are the official names of this protein?
Endoplasmic reticulum chaperone BiP, 78 kDa glucose-regulated protein, GRP-78, Binding-immunoglobulin protein, BiP, Heat shock protein 70 family protein 5, HSP70 family protein 5, Heat shock protein family A member 5, Immunoglobulin heavy chain-binding protein.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen. Melanosome. Cytoplasm. Cell surface. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV (By similarity). Localizes to the cell surface in epithelial cells; high levels of free iron promotes cell surface localization (By similarity).
Protein: PRDX4_MOUSE
Sequence: MEARSKLLDGTTASRRWTRKLVLLLPPLLLFLLRTESLQGLESDERFRTRENECHFYAGGQVYPGEASRVSVADHSLHLSKAKISKPAPYWEGTAVINGEFKELKLTDYRGKYLVFFFYPLDFTFVCPTEIIAFGDRIEEFKSINTEVVACSVDSQFTHLAWINTPRRQGGLGPIRIPLLSDLNHQISKDYGVYLEDSGHTLRGLFIIDDKGVLRQITLNDLPVGRSVDETLRLVQAFQYTDKHGEVCPAGWKPGSETIIPDPAGKLKYFDKLN
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events (PubMed:11229364).  Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation (By similarity).
What are the official names of this protein?
Peroxiredoxin-4, Antioxidant enzyme AOE372, Peroxiredoxin IV, Prx-IV, Thioredoxin peroxidase AO372, Thioredoxin-dependent peroxide reductase A0372, Thioredoxin-dependent peroxiredoxin 4.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum. Note=Not secreted.
Protein: SYI_PYRAE
Sequence: MPHGDLPLPPSYRPHEVKKAVEEFWRRNRIFEKWKSWRGGPKFTFLEGPPTTNGMPHVGHIRGRTYKDVVIRFYRLLGYDVWVQGGWDMQGMPVEWEVEKKLKLRSKKDIEQFGLEKFALECNSLVEEYLAYWREWGTKRLGLWLDLENAYETRQPHYLQYAWRIVKRAHELGLLTEDYRVLWFCPRCETSLSDHEVALGYDEREDPSIYVKFRVEGGVDEYLVIWTTTPWTIVDNEAVAVHPDYVYAKVEVEVGGRREYWWLAEALVPSLMAKFGIKTWRVVETKKGVELAGVRYIHPLAEEVPERASRPHQVVTAEFVTLEQGTGLVHIAPGHGPEDFELAKKYGLPVTNSVEINGIYNELGGRYKGKHVYDVDKEVTRDLRSKGLLVFEEKIRHEYPHCWRCGSKLILRADRQWFIAISRIRDKMYAELQKVNVVPTKLRDRFDIFVQNARDWNISRSRVWGTPLPVWRCKKDGRILVIGSLEELKKLAKELPPVDDFKLVHRPWIDQVKISAHDCDEWVREPYVMDVWLDSGIAWIAAVDGENNRDLWEKLFPYDFVTEGIDQTRGWFYSLLATSVLYTGRAPYKNVLIQGLILDKHGQKMSKSKGNVIWAKDLFEKYGADPVRLYILSKVAPWEDLSFDPDEVKYVIGDLNILWNVVKFADTYMSLDGFDAEKYPLSQWLEKGLEEDKWILSELNIMISEFTNFVKNFEFHKAAALWREFVVETLSHRYIRLLRRRVWSEEPSPDKYAAYAVLHDVLKKVLILGSILVPFITEYLWQAYVRKYEKNAPESVHLAQYPAAGSYDKELIYAYRELFAVFSALAEARNKAGIKLRWPIREAYVNGAKYAERYTELLKYLGNVKEVKVGRRPDYLCVKEGELEVCVPDKIEPELYYEALARELIRRIQVMRKETGLEISDEIHVVVETNSDDIKKAVEQYRDYIARETRAVKLIIDAVSQGKEWDISGEKVKIEIRKAQA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FRE_ECOL6
Sequence: MTTLSCKVTSVEAITDTVYRVRIVPDAAFSFRAGQYLMVVMDERDKRPFSMASTPDEKGFIELHIGASEINLYAKAVMDRILKDHQIVVDIPHGEAWLRDDEERPMILIAGGTGFSYARSILLTALARNPNRDITIYWGGREEQHLYDLCELEALSLKHPGLQVVPVVEQPEAGWRGRTGTVLTAVLQDHGTLAEHDIYIAGRFEMAKIARDLFCSERNAREDRLFGDAFAFI
What is the function of this protein?
Catalyzes the reduction of soluble flavins by reduced pyridine nucleotides.
What are the official names of this protein?
NAD(P)H-flavin reductase, Aquacobalamin reductase, FMN reductase, Ferrisiderophore reductase C, NAD(P)H:flavin oxidoreductase, Riboflavin reductase [NAD(P)H].
What is the protein family that this protein belongs to?
Belongs to the Fre/LuxG FAD/NAD(P) flavoprotein oxidoreductase family.
Protein: RS18_XYLFT
Sequence: MSKFFRRRKFCKFTAEGIKEIDYKDLNTLRQYLTENGRIVPSRVTGTKSKYQRQLTTAVKLARFLALIPYTDNHDI
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: MDTD_ECO55
Sequence: MTDLPDSTRWQLWIVAFGFFMQSLDTTIVNTALPSMAQSLGESPLHMHMVIVSYVLTVAVMLPASGWLADKVGVRNIFFTAIVLFTLGSLFCALSGTLNELLLARALQGVGGAMMVPVGRLTVMKIVPREQYMAAMTFVTLPGQVGPLLGPALGGLLVEYASWHWIFLINIPVGIIGAIATLMLMPNYTMQTRRFDLSGFLLLAVGMAVLTLALDGSKGTGLSPLAIAGLVAVGVVALVLYLLHARNNNRALFSLKLFRTRTFSLGLAGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAGLMMIPMVLGSMGMKRIVVQVVNRFGYRRVLVATTLGLSLVTLLFMTTALLGWYYVLPFVLFLQGMVNSTRFSSMNTLTLKDLPDNLASSGNSLLSMIMQLSMSIGVTIAGLLLGLFGSQHVSIDSGTTQTVFMYTWLSMALIIALPAFIFARVPNDTHQNVAISRRKRSAQ
What are the official names of this protein?
Putative multidrug resistance protein MdtD.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: H2D01_CYRHA
Sequence: MTLIAILTCAAALVLHTTAAEELEAESQLMEVGMPDTELEAVDEERLFECSVSCEIEKEGNKDCKKKKCKGGWKCKFNMCVKI
What is the function of this protein?
Postsynaptic neurotoxin.
What are the official names of this protein?
U4-theraphotoxin-Hhn1x, U4-TRTX-Hhn1x, Hainantoxin-II-4, HNTX-II-4.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 12 (Hwtx-2) family. 02 (Hwtx-2) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CAHZ_DANRE
Sequence: MAHAWGYGPADGPESWAESFPIANGPRQSPIDIVPTQAQHDPSLKHLKLKYDPATTKSILNNGHSFQVDFVDDDNSSTLAGGPITGIYRLRQFHFHWGSSDDKGSEHTIAGTKFPCELHLVHWNTKYPNFGEAASKPDGLAVVGVFLKIGAANPRLQKVLDALDDIKSKGRQTTFANFDPKTLLPASLDYWTYEGSLTTPPLLESVTWIVLKEPISVSPAQMAKFRSLLFSSEGETPCCMVDNYRPPQPLKGRKVRASFK
What is the function of this protein?
Reversible hydration of carbon dioxide.
What are the official names of this protein?
Carbonic anhydrase, Carbonate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the alpha-carbonic anhydrase family.
Protein: PTH_CLOBJ
Sequence: MYLVVGLGNIGKEYKKTRHNIGFDVVDIIAEKYNIEINRQKFKGSYGEGRIGNEKIILLKPSTYMNLSGESVIEAANFYKIDKENIIVIYDDMSIDIGKLRVRGKGSAGGHNGIKNIIQHLNSDIFPRVRVGIGQPDENVVNYVLGKFSKDEREIIEKVLAMSAKACISIVEDGVTEAMNKYNGVKIEV
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOZ_STAAN
Sequence: MLNPPLNQLTSQIKSKYLIATTAAKRAREIDEQPETELLSEYHSFKPVGRALEEIADGKIRPVISSDYYGKE
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: MURG_THEAB
Sequence: MIKIAVAGGVTGGHLYPALAVLKELEKLTPIDVLYFTVSGKLEERVLKDYNYKKVSLKIQGLKRPVYSIENIKRLFKIFNANNIVLKELKKFKPDIVFVTGGYVSYPVGTAAKKLKIPLYIQEQNVIPGLANIKLSSFAKKVFVSFEESKKYFQRDVVVAGNPILICHKENLNFEKKTILIVGGSGGSEFLNSLACKLSNKLKDYHFILSSGRKEVPCKSENLTILDYIENMSDYYSAVSCAITRGGATTVSELIFFDTPSIIIPWEGSTEAHQIENAKQIEKLGLGYVIREKEVNIDEIANKIIELSNRERKGSPKTNPAILIAKEIKNEVLK
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y122_CAEEL
Sequence: MNLYQVNELFVDVYSKQDYTDESQSRNRSSVRKIAWLELRGQKRIFVGDVRNGLNTSGLTKASSICSGVMEIPGYVVLLALGTLQSINAQPLSMEVGASWCGGASPALPWAH
What are the official names of this protein?
Uncharacterized protein from transposable element Tc1.
Protein: ARGB_ACET2
Sequence: METSMETVIKKAEILIEALPYIQKLYGKTVVIKYGGNAMINEELKTSVMEDITLLKYIGMNPVVVHGGGPDINKALDKFNIKSRFINGLRLTDKATMDVAQMVLVGKTNKEIVSILNQMGGKAVGICGIDGNVIECEQYKTTIDGQETDLGYVGKITNINSKLIELLAKDEYIPVIAPIGIGKDGQSYNINADTVAGEIAAALKAEKLMLLTDVPGVKKNKDSDEIIPALTSAEALELINKKIIDGGMIPKVLGCIEALEKGVGRTHIIDGRIPHCLLLEIFTNKGIGTMIMKEKILYYEGEKL
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PXL2A_CHICK
Sequence: MSFLPDFGIFTMGMWSVGLGAVGAAITGIVLANTDLFLSKPEKATLEFLEAIELKTLGSEPRTFKASELWKKNGAVIMAVRRPGUFLCREEASELSSLKPQLSKLGVPLYAVVKEKIGTEVEDFQHYFQGEIFLDEKRSFYGPRKRKMMLSGFFRIGVWQNFFRAWKNGYSGNLEGEGFTLGGVYVIGAGRQGILLEHREKEFGDKVSLPSVLEAAEKIKPQAS
What is the function of this protein?
Involved in redox regulation of the cell.  Acts as an antioxidant.  Inhibits TNFSF11-induced NFKB1 and JUN activation and osteoclast differentiation.  May affect bone resorption and help to maintain bone mass (By similarity).
What are the official names of this protein?
Peroxiredoxin-like 2A, Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes, Protein PAMM, Redox-regulatory protein FAM213A.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin-like PRXL2 family. PRXL2A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPF2_SALTI
Sequence: MNAAIFRFFFYFST
What are the official names of this protein?
Phenylalanyl--tRNA ligase operon leader peptide, pheST attenuator peptide.
Protein: TRMB_BACAC
Sequence: MRLRHKPYAMDRINEYSHIVIGNPEERAGNWKEVFGNEQPIHIEVGTGRGRFMYDMAKANPHINYIGIEKFTSVVVDALDKLIEEELPNLKLINKDAEDLTVFFAKGEIDRVYLNFSDPWPKKRHTKRRLTYKTFLRNYEEVLVEGGEIHFKTDNQGLFEYSLMSMAEYGMLLTYLSLDLHNSDFEGNIMTEYEEKFSSKGHRIYRVEAKYRTEPMQ
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: CAS5_METJA
Sequence: MIMEALVALLRFPFYSFGKQSYQVRQSLLLPSPSALKGALAKGIILLGGKKGKSLDEIAKKTVEELENKLIYVGAKPYKSSIIKTPILLKRLRNLEDQKNPEKSDAMRREYVFAREILAIYVFRRKLSEEEKDLMLKAVYLIDQLGDTECVGNVIKTEWVEVKEEKAPLKTYVKFKKVSKMSINGGIIENMLETPNFGNKVKEEPYLLPLIEKRYRRSSYYVESDRIFDGNYKIIAFDEVIGLWI
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) (By similarity).
What are the official names of this protein?
CRISPR-associated protein Cas5.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated protein Cas5 family. Subtype I-A/Apern subfamily.
Protein: ALDH_LINUS
Sequence: MYRPLVARLLRDSVATRKGSSHFARRFSHSLPFATVDAEELSGAKPAEVLNLVQGNWGGSSSWHTVVDPLNGEPFIKVAEVDETEIKPFVESLSKCPKHGLHNPFKSPERYLLYGDISTKAGHMLSIPKVSEFFARLIQRVAPKSYHQALGEVQVTQKFFENFTGDQVRFLARSFGVPGNHLGQQSNGFRWPFGPVAIITPFNFPLEIPVLQLMGALYMGNKPLLKVDSKVSIVMEQMMRLLHYCGLPVGDADFVNSDGKAMNKILLEANPRMTLFTGSSRVAEKLALDLKGRIKLEDAGFDWKILGPDVNEADYVAWVCDQDAYACSGQKCSAQSILFMHENWAATPLISRLKELAERRKLEDLTVGPVLTVTTEAMLDHLNKLLQIPGAKLLFGGKPLENHTIPSIYGAVKPTAVYVPLEEILKVSNYELVTKEIFGPFQVVTEYKNSQLPMVLEALERMHAHLTAAVVSNDQLFLQEVIGNTVNGTTYAGLRARTTGAPQNHWFGPAGDPRGAGIGTPEAIKLVWSCHREIIYDIGPVSHHWEIPPST
What is the function of this protein?
Could be involved in facilitating the biotrophic relationship between the plant and the rust fungus.
What are the official names of this protein?
Probable aldehyde dehydrogenase, Flax-inducible sequence 1.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: DUT_ESCF3
Sequence: MKKIDVKILDPRVGKEFPLPTYATSGSAGLDLRACLDDAVELAPGDTTLVPTGLAIHIADPSLAAMMLPRSGLGHKHGIVLGNLVGLIDSDYQGQLMISVWNRGQDSFTIQPGERIAQMIFVPVVQAEFNLVEDFDATDRGEGGFGHSGRQ
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: MLTF_VIBVY
Sequence: MPIFNLHQLRNFLFIIATTLFLSACQIESKPTSELDQIKQRGVLRVGTLNNQLSYYIGPDGQTGLDYELARQFADELGVKLEVKVAFRQAELFPMLKRGDIDLIATGLNQTPRAIKQFRPGPSYYYVSQVVVYKNGALRPRNLKQLVEYQNAKTASEDEAEASNNAAANTLQVVKQSQNVTLLKSLQSDYPELQFTTVSDADNYDLLRRVSTGELRFAISDSIELSLAQRLYPDLATAFEVTEDQPVSWFVRRSPDESLYALMIEFFGNISQSGELARLEEKYIGHIGSFDYVDTRAFIRALDNKLPKWAPLFEQYSAEFDWRLIAALAYQESHWNPLAKSPTGVRGMMMLTLPTAQSVGVKNRLDPEQSIRGGVEYLRRIVARVPESIPQHEKIWFALASYNVGFGHMMDARRLTKRQGGDPDSWGDVKERLPLLRQKKYFSQTRYGYARGDEAKNYVENIRRYYQSIIGHVGQNSLIASDQEGEIQVIPPLENSELVAASDIDAAENEALSPDVGVSQATLTTEVQP
What is the function of this protein?
Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product.  Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus.  Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase F, Murein lyase F.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane.
Protein: COAD_BACAA
Sequence: MTSIAISSGSFDPITLGHLDIIKRGAKVFDEVYVVVLNNSSKKPFFSVEERLDLIREATKDIPNVKVDSHSGLLVEYAKMRNANAILRGLRAVSDFEYEMQITSMNRKLDENIETFFIMTNNQYSFLSSSIVKEVARYGGSVVDLVPPVVERALKEKFQTPLK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_BREBN
Sequence: MAREFSLPNTRNIGIMAHIDAGKTTTTERILFYTGRVHKIGEVHEGAATMDWMEQEQERGITITSAATTAQWNGHRINIIDTPGHVDFTVEVERSLRVLDGAVTVFDAKGGVEPQTETVWRQADRYGVPRMCYINKMDIMGANFDMCLGQIKSRLGANPVAIQYPIGAEDQFKGMVDLIEMKAIVYTDDLGKTSDSAEIPADLLARCEELRMAMVEAAAEQDEELMMKYLEGEELTNDEIRAALRKGTIDCKLTPVMCGSSYKNKGVQPMLDNVVAYLPSPVDIPAIKGTLPDTEDEVDRPADDNGPFSALAFKIMTDPYVGRLTFFRVYSGVLNSGSYVLNSTKGKRERVGRILQMHANHREEITTVYSGDIAAAVGLKDTTTGDTLCDEKAPVILESMDFPEPVISVAIEPKSKADQDKMGIGLSKLAEEDPTFRTRTDEETGQTIISGMGELHLEIIVDRLKREFKVESNVGAPQVAYRETFRNAAKVEGKFVRQSGGRGQYGHVWVEFAPLEAGQGFQFENKIVGGVVPREYIPAVQAGIEESMKNGVIAGFPLVDIKATIVDGSYHDVDSNEMAFKVAGSLALKEAAKKCGAVLLEPIMKVEVTMPEEYMGDVMGDLNSRRGRIEGMEARANAQVIRAMVPLSEMFGYSTILRSRTQGRGVYSMVIDHYEEVPKFIAEEIIKKSKGE
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YWZ1_CAEEL
Sequence: MPRKLLEERSTGSATKWLREEEKIEKKSRADQLKIKFMQTRDNSDINSIFSEPPSEFSVLCDDDDCDKGSVVSSTLTTSIRKTFSSFRFDENQRKKGTRKRRSSEVDSKEKS
What are the official names of this protein?
Uncharacterized protein C02B8.1.
Protein: LPXC_BLOFL
Sequence: MIKQRTLKNIVCTTGIGLHTGQEVTLTLYPALANTGIIYRRIDLNPPVDFCVNIESVGSTFLCTCLKNNTYGVQVLTVEHLSAAQSGLGIDNIIIELNGPEVPIMDGSADPFVSLLLKAGIKELNSSKNFFRLKQIVRVEDGDRWAELRPFNGFTLDFTIDYDHPVVNMKNKHYFFNFTSKSFRSEISSARTFGFVDNIQKLKNCGFVLGGSLTSSVVMDKYQVVNSEGLRFNNELVRHKILDAVGDLFMCGYNLIGSFIGFKSGHTLNNKLLRAVLARRKAWEITSCIQGCDVSKIF
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.