PharMolix/UniProtQA huggingface dataset:
Protein: PRIO_BOSIN
Sequence: MVKSHIGSWILVLFVAMWSDVGLCKKRPKPGGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGGWGQGGTHGQWNKPSKPKTNMKHVAGAAAAGAVVGGLGGYMLGSAMSRPLIHFGSDYEDRYYRENMHRYPNQVYYRPVDQYSNQNNFVHDCVNITVKEHTVTTTTKGENFTETDIKMMERVVEQMCITQYQRESQAYYQRGASVILFSSPPVILLISFLIFLIVG
What is the function of this protein?
Its primary physiological function is unclear.  Has cytoprotective activity against internal or environmental stresses.  May play a role in neuronal development and synaptic plasticity.  May be required for neuronal myelin sheath maintenance.  May play a role in iron uptake and iron homeostasis.  Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).  Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts.  Also provides Cu(2+) or Zn(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains (By similarity).
What are the official names of this protein?
Major prion protein, PrP.
What is the protein family that this protein belongs to?
Belongs to the prion family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Golgi apparatus. Note=Targeted to lipid rafts via association with the heparan sulfate chains of GPC1. Colocates, in the presence of Cu(2+), to vesicles in para- and perinuclear regions, where both proteins undergo internalization. Heparin displaces PRNP from lipid rafts and promotes endocytosis.
Protein: EFTS_SPHAL
Sequence: MAEITAALVKELRDRTGAGMMDCKKALAENNGDIEASIDWLRTKGLAAAAKKAGRVAAEGLVGFATDGTRGALVEVNSETDFVGKNEQFQAFVRDVTQVALAEGITDIDALAAAPYPTGGTVAEQLTSNIATIGENQSLRRVALLTVNSGAVTGYVHNAAAPGMGKIGVLVALESSAGADVLEPLGKQLAMHVAAANPLALNGDDLDADLVARERAIAEEKAAQSGKPAEIVAKMVDGAIAKFRKENALLSQLFVMDGKTPVAEVVAAAGKDVGAAITLKGFVRFQLGEGIEKEESDFAAEVAAAAGV
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YWZD_BACSU
Sequence: MSEKKLNQEEFLKILMHAHEIGEQSSEMTTKEMLENLISHIKNGYAT
What are the official names of this protein?
Uncharacterized protein YwzD.
Protein: Y093_MYCTU
Sequence: MLAQATTAGSFNHHASTVLQGCRGVPAAMWSEPAGAIRRHCATIDGMDCEVAREALSARLDGERAPVPSARVDEHLGECSACRAWFTQVASQAGDLRRLAESRPVVPPVGRLGIRRAPRRQHSPMTWRRWALLCVGIAQIALGTVQGFGLDVGLTHQHPTGAGTHLLNESTSWSIALGVIMVGAALWPSAAAGLAGVLTAFVAILTGYVIVDALSGAVSTTRILTHLPVVIGAVLAIMVWRSASGPRPRPDAVAAEPDIVLPDNASRGRRRGHLWPTDGSAA
What are the official names of this protein?
Uncharacterized protein Rv0093c.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HISX_YERPE
Sequence: MQPTNFNTLINWQQCSEEQQKALLSRPAINASERITAAVSDILDRVKAEGDSALRDFSQRFDHVQVADIRITASEIAAASARLSDDVKHAMAQAVRNIEIFHNAQKMPVVDVETQPGVRCQQITRPIASVGLYIPGGSAPLPSTVLMLGTPARIAGCQRVVLCSPPPIADEILYAAQLCGIQEVFQIGGAQAIAAMAFGSESVPKVHKIFGPGNAYVTEAKRQVSQRLDGAAIDMPAGPSEVLVIADSGATPAFIAADLLSQAEHGPDSQVILLTPDAAIAQAVAVEVEQQLALLSRADIARQALESSRLIVTNDLQQCIDISNAYGPEHLILQIRQPEEIIDQIDNAGSVFMGDWSPESAGDYASGTNHVLPTYGYTSTYSSLGLADFVKRMTVQQLTPQGLLGLASTIETLAQAEQLTAHKNAVTLRVTALNNALTAVNKE
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: Y390_LATSS
Sequence: MTETNKNIHQEAEQEITLIDDQGNEELYQVLFTFDSEDYGKSYVLLYPASSAEDEEVDIQAFAFTSDVAGDASQGDLFPIEDDEEWEMVEEVLNTFLADDNMQ
What are the official names of this protein?
UPF0473 protein LCA_0390.
What is the protein family that this protein belongs to?
Belongs to the UPF0473 family.
Protein: GLMM_METVS
Sequence: MKLFGTSGIRMKNLDPLIAYKVGFAISKNFKKAVIGRDTRTTGNLIESAITAGLLNGGCDVTILGIVPTPVLGFSAKSHDIGIMITASHNPPEYNGIKLFNNNGTSFTPNQEESLEEIIEKSDFLDPSWDIVGNVSEDKTAVKKYLDYILSNINIKKKFNVVVDCANAAACGISPNLFTNAGCKVISVNSHCDGRFVGRMPEPNEKNLVETVDIVKGLNLSGRDFIGIAHDGDADRMIAIDEMGRVTDFDKLLAAFCKYVVQKTNAKKIVTTVDASMAIEEYLKEFGAEVIRTKIGDVSVAYEIEKTGAIFGGEPSGTWIHKSIHLTPDGILSGLRVLEMMEFYDKRLCEIMDEVPSYINLREKLPCPDELKNKVMKYVSKEGKLLFKKEPETLDGVRFSFENGWILIRPSGTESYIRVRVEAKDETFANELLNNGISLVNNGILK
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: NIMT_ECOLI
Sequence: MTCSTSLSGKNRIVLIAGILMIATTLRVTFTGAAPLLDTIRSAYSLTTAQTGLLTTLPLLAFALISPLAAPVARRFGMERSLFAALLLICAGIAIRSLPSPYLLFGGTAVIGGGIALGNVLLPGLIKRDFPHSVARLTGAYSLTMGAAAALGSAMVVPLALNGFGWQGALLMLMCFPLLALFLWLPQWRSQQHANLSTSRALHTRGIWRSPLAWQVTLFLGINSLVYYVIIGWLPAILISHGYSEAQAGSLHGLLQLATAAPGLLIPLFLHHVKDQRGIAAFVALMCAVGAVGLCFMPAHAITWTLLFGFGSGATMILGLTFIGLRASSAHQAAALSGMAQSVGYLLAACGPPLMGKIHDANGNWSVPLMGVAILSLLMAIFGLCAGRDKEIR
What is the function of this protein?
Involved in efflux of 2-nitroimidazole.
What are the official names of this protein?
2-nitroimidazole transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Cyanate porter (TC 2.A.1.17) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CH60_DEIRA
Sequence: MAKQLVFDESARRSLERGVNAVANAVKVTLGPRGRNVVIEKKFGSPTITKDGVTVAKEVELEDKLENIGAQLLKEVASKTNDITGDGTTTATVLGQAIVKEGLRNVAAGANPLALKRGIDKAVAVAIEEIKKLAVSVEDSEAIKKVAGISANDETVGQEIASAMDKVGKEGVITIEESKGFDTEVDVVEGMQFDKGFINPYFITNPEKMEAVLEDAYILINEKKISNLKDMLPVLEKVAQTGRPLLIIAEDVEGEALATLVVNKLRGTLNIAAVKAPGFGDRRKEMLRDIAAVTGGEVVSEDLGHKLENVGMEMLGRAARIRITKDETTIVDGKGEQAQIDARVNAIKGELDSTDSDYAREKLQERLAKLSGGVAVIRVGAATETELKEKKHRYEDALSTARSAVEEGIVAGGGTTLLRVIPAVRKAAESLTGDEATGARILIRALEEPARQIAANAGEEGSVIVNAVVGSDKARYGFNAATGEYVEDMVAAGIVDPAKVTRTALQNAASIGALILTTEAIVSDKPEKAAPAMPQGGGDMGGMGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_SYNFM
Sequence: MNDTTAKTLNCSPASRDGFPETLGDFGRTRVDLPVVLVAGPTGVGKTAFAVELARALGSEIVNADSMQVYRHMDIGTAKPTPRERSAVPHHLIDIVDPDEPFDAGDYLARARPVIATLHEAGKVPIVVGGTGLYLKVLTRGICAGAPGDPDVRRRLIEEELTLGLPALHERLRDVDPPLGARIHPNDRQRILRALEVFHHSGKPLSYWQRQHRFEDAPYRTLKIFLHRPREVLYARINDRVDAMMAQGFLDEVRNLLAMGCGPELKPMQSLGYRQMARHLRGEMSLDEAVNEIRRDTRRYAKRQLTWFRADPEYRWFDAADTHGLVARIVRETPDLHDNRLR
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: AR273_ARTOA
Sequence: MFENTLQGALIGVTVIPTLILSLPTTSFVRYAIYPLPALLVLRALLWPPTEGLAKETYLLGLLMTDTSFKMFDYLYLQGYNAPAKFLQVDRVGRTITKVHEYPKDTLGQVKWALSLVTSHRGIGWNIQVPLQKIKYPSSRVAYIFESMVSILSIYLGLYTCGSLCDYMVQVLRKEADSPYPWVYGLFKNSIFQMVVAFMGIFAMVSNSVLVYNLARMICVTSGIKGDWGKIESWPNMFGGFEDAWSIRNVWGRAWHQNLRRCLTAPGEKVSSLIFGSSPKLGRVPRLIRRYFLVFSAFGVSGLLHSLAVYYGSKTDTMPYEDSTPLHMRPGWYVTGYFFYIQPFAITLEDFICWATGTSTESKGVKATKVRWFVGMVYTLTWFTWGTAVLWIHPQLASLGYQRTSDAELGYVHILVSTSEAASILPLNPWPAVVKTVSPTFWDVYGYFKSSGLGGYLYLYAYTTLEILGGSGFNVLKSASSVV
What is the function of this protein?
Acetyltransferase; part of the gene cluster that mediates the biosynthesis of sesquiterpenyl epoxy-cyclohexenoids (SECs) such as anthrobotrisins and arthrosporols, metabolites that possess a novel hybrid carbon skeleton consisting of a polyketide-derived epoxycyclohexenol combined with a terpenoid-derived monocyclic sesquiterpenol substructure (PKS-PTS hybrid) (PubMed:33823587).  The SEC pathway plays an important role for fungal soil colonization via decreasing fungal nematode-capturing ability (PubMed:33823587).  The role of the acetyltransferase in SEC biosynthesis has still to be determined (Probable).  The pathway begins with the biosynthesis of 6-methylsalicylic acid (6-MSA), the first precursor of the polyketide-derived epoxycyclohexenol in arthrosporols, by the polyketide synthase (PKS) AOL_s00215g283 via condensation of 1 acetate and 3 malonate units.  The 6-methylsalicylic acid decarboxylase AOL_s00215g281 then catalyzes the decarboxylation of 6-methylsalicylic acid to yield m-cresol.  The cytochrome P450 monooxygenase AOL_s00215g282 further oxidizes m-cresol to yield toluquinol.  With the assistance of the oxidoreductase AOL_s00215g277, the polyprenyl transferase AOL_s00215g276 catalyzes the farnesylation of toluquinol to produce farnesyl hydroquinone, the hybrid precursor for biosynthesis of SECs.  Farnesyl hydroquinone undergoes epoxidation and then subsequent dehydrogenation to form farnesyl epoxy-quinone, the first and simplest SEC.  The cytochrome P450 monooxygenase AOL_s00215g278 and the FAD-dependent monooxygenase AOL_s00215g279 might be involved in the oxygenation of the phenol moiety, most likely in the epoxy formation.  The cytochrome P450 monooxygenases AOL_s00215g274 and AOL_s00215g280 are involved in specific regional ketone reductions at respectively C-4 and C-1 of farnesyl epoxy-quinone PubMed:33823587 (Probable).
What are the official names of this protein?
Acetyltransferase AOL_s00215g273, Sesquiterpenyl epoxy-cyclohexenoids cluster protein AOL_s00215g273, SECs cluster protein AOL_s00215g273.
What is the protein family that this protein belongs to?
Belongs to the wax synthase family.
Protein: IF2_STRPQ
Sequence: MSKKRLHEIAKEIGKSSKEVVEHAKYLGLDVKSHASSVEEADAKKIISSFSKASKPDVTASQTVKPKEVAQPSVTVVKETGSEHVEKTQVSKPKSRNFKAEREARAKEQAARKQANGSSHRSQERRGGYRQPNNHQTNEQGDKRITHRSQGDTNDKRIERKASNVSPRHDNHQLVGDRNRSFAKENHKNGRFTNQKKQGRQEPQSKSPKIDFKARAAALKAEQNAEYSRQSETRFRAQQEAKRLAELARQEAKEAALKAQAEEMSHREAALKSIEEAETKLKSSNISAKSTADNRRKKQARPEKNRELTHHSQEGQKKNKKSWNSQNQVRNQKNSNWNKNKKTKKGKNAKNTNTAPKPVTERKFHELPKEFEYTEGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGDTIELLMVDYGIEAKAKVEVDDADIERFFEDENYLNPENIVERAPVVTIMGHVDHGKTTLLDTLRNSRVATGEAGGITQHIGAYQIEEAGKKITFLDTPGHAAFTSMRARGASVTDITILIVAADDGVMPQTIEAINHSKAAGVPIIVAINKIDKPGANPERVIAELAEYGIISTAWGGECEFVEISAKFNKNIDELLETVLLVAEVEELKADPTVRAIGTVIEARLDKGKGAIATLLVQQGTLHVQDPIVVGNTFGRVRAMVNDLGRRVKSAEPSTPVSITGLNETPMAGDHFAVYADEKAARAAGEERSKRALLKQRQNTQRVSLDNLFDTLKAGEIKTVNVIIKADVQGSVEALAASLVKIEVEGVRVNVVHSAVGAINESDVTLAEASNAVIIGFNVRPTPQARQQADTDDVEIRLHSIIYKVIEEVEEAMKGKLDPVYQEKILGEAIIRETFKVSKVGTIGGFMVINGKVTRDSSVRVIRDSVVIFDGKLASLKHYKDDVKEVGNAQEGGLMIENFNDLKVDDTIEAYIMEEIVRK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_BACC3
Sequence: MARSLKKGPFVDDHLMSKIAKLNETEQKQVVKTWSRRSTIFPQFIGHTIAVYDGRKHVPVYVTEDMVGHKLGEFAPTRTYKGHDADDKKTRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: FLA15_ARATH
Sequence: MDDLSKLLFFLLLTISITTALPDKPGSGQINSNSVLVALLDSHYTELAELVEKALLLQTLEEAVGQHNITIFAPRNDALEKNLDPEFKSFLLQPKNLKSLQSLLMFHILPKRITSPQFSSAVVSHRTLSNDHLHFTNGKVNSAEITKPDDLTRPDGIIHGIERLLIPRSVQEDFNRRRSLRSIAAVLPEGAPEVDPRTHRLKKKPAPIPAGAPPVLPVYDAMSPGPSLAPAPAPGPGGPRHHFNGEAQVKDFIHTLLHYGGYNEMADILVNLTSLATEMGRLVSEGYVLTVLAPNDEAMAKLTTDQLSEPGAPEQIMYYHIIPEYQTEESMYNSVRRFGKIRYDSLRFPHKVEAQEADGSVKFGHGDGSAYLFDPDIYTDGRISVQGIDGVLFPEEKTPVEKKTGVPVVKKAPKPRRGKLMEVACTMLGSQFPTCQ
What is the function of this protein?
May be a cell surface adhesion protein.
What are the official names of this protein?
Fasciclin-like arabinogalactan protein 15.
What is the protein family that this protein belongs to?
Belongs to the fasciclin-like AGP family.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRDB_BACCL
Sequence: MNRLAVELPGLSLKNPIMPASGCFGFGREYARFYDLSVLGAIMIKATTKEPRFGNPTPRVAETPGGMLNAIGLQNPGLDKVLEEELPWLEQFDVPIIANIAGSTVEEYVEVAEAISKAPNVHALELNISCPNVKKGGIAFGTVPDVAAELTRLVKEVAAVPVYVNVSPNVTDIVAMAKAIEQAGADGLTMINTLVGMRIDVKTGRPILANGTGGLSGPAVKPIAIRMIYEVSQAVSIPIIGMGGIQTAEDVLEFFYAGASAVAVGTANFVDPFVCPTIIADLPALLDDLGIGHISECIGRSWKTGAHAVHCRA
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit, DHOD B, DHODase B, DHOdehase B, Dihydroorotate oxidase B, Orotate reductase (NADH).
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1738_MYCBO
Sequence: MMAEPEESREPRGIRLQKVLSQAGIASRRAAEKMIVDGRVEVDGHVVTELGTRVDPQVAVVRVDGARVVLDDSLVYLALNKPRGMHSTMSDDRGRPCIGDLIERKVRGTKKLFHVGRLDADTEGLMLLTNDGELAHRLMHPSHEVPKTYLATVTGSVPRGLGRTLRAGIELDDGPAFVDDFAVVDAIPGKTLVRVTLHEGRNRIVRRLLAAAGFPVEALVRTDIGAVSLGKQRPGSVRALRSNEIGQLYQAVGL
What are the official names of this protein?
Uncharacterized RNA pseudouridine synthase Mb1738, RNA pseudouridylate synthase, RNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RsuA family.
Protein: HSL46_DICDI
Sequence: MTLFSSISSISNPMTSSKSIIASFGSGTIMSSNSIACGSGCGGGRGGILGLGLGLGLNLFGGSRGACGGNGGSGNPAQGGNGSCCGGPCCGI
What are the official names of this protein?
HssA/B-like protein 46.
What is the protein family that this protein belongs to?
Belongs to the hssA/B family.
Protein: NSRR_PECCP
Sequence: MQLTSFTDYGLRALIYMASLPGGKMTSISEVTEVYGVSRNHMVKIINQLSRAGLVMAVRGKNGGIRLGKPAETIRIGDVVRELEPLTLVNCSHEFCHITPACRLKQVLQQAVQNFLQELDQYTLADMVKENPPLYKLLLVE
What is the function of this protein?
Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress.  May require iron for activity.
What are the official names of this protein?
HTH-type transcriptional repressor NsrR.
Protein: GPMA_ECO8A
Sequence: MAVTKLVLVRHGESQWNKENRFTGWYDVDLSEKGVSEAKAAGKLLKEEGYSFDFAYTSVLKRAIHTLWNVLDELDQAWLPVEKSWKLNERHYGALQGLNKAETAEKYGDEQVKQWRRGFAVTPPELTKDDERYPGHDPRYAKLSEKELPLTESLALTIDRVIPYWNETILPRMKSGERVIIAAHGNSLRALVKYLDNMSEEEILELNIPTGVPLVYEFDENFKPLKRYYLGNADEIAAKAAAVANQGKAK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: RS9_BURP0
Sequence: MIGNWNYGTGRRKSAVARVFIKAGKGDIVVNGKPISDYFSRETSLMIVRQPLELTNHAQTFDIKVNVSGGGETGQAGAVRHGITRALIDYDATLKPALSNAGFVTRDAREVERKKVGLHKARRAKQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: INSR2_HUMAN
Sequence: MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQASALSLSSSTSTWPEGLDATARAPPALVVTANIGQAGGSSSRQFRQRALGTSDSPVLFIHCPGAAGTAQGLEYRGRRVTTELVWEEVDSSPQPQGSESLPAQPPAQPAPQPEPQQAREPSPEVSCCGLWPRRPQRSQN
What are the official names of this protein?
Insulin, isoform 2, INS-IGF2 readthrough transcript protein.
Protein: YJD1_SCHPO
Sequence: MKLKVSIGCDAQHTQIAWVNYEGRPTEVDGPLWVGRILVRVRDFDGFTPDGSPPKRDSEYFRGRSRKFQIQAEGRFKKEYNGDQVIYGTQFDHMISTFPESAFRAGMRIAKYIDPAVYYDKYARSPYIMSPFVACVNTLSAWPAPSRLEDAVISLVEADSQESDTESLPEINDSSDVSLSDLPSTNVTPKKTTTQIDVQTNIVTPPITVTAVPDSPNPPAATPATVADNDDLSIVSSDSGNTTAPRKNRHRYWSFAGFSDSTRFSHLNVPAAIPDAPSVKTETSQNVSQLSVKSAATSLAPVEDDEDDELLLHRHITNKHKDFNLHVKQLGLLHKPSLDLEEGYIMDENYGKDVYKHGISNVPDDENEDDLQRYFTALEMQQDQKEQHKKSKNKDPFRKITHPSLHLGKFSTPKLIKRMSLRSKKSLRNDSKSDDVGNSTHRFSTASAASTSAVKTEKEKKMSAPRRSLDKLIRIGSLHRHHHHHHKTDLIESDSGIEASESNRRKSDIFSFSGRNSFSVSRPSSSHSTLSYANDSASSAVNVAGETGSLPPLREQTSITSGVPPSNRLKKHVSTPEKIVEERSIDEVSQSNTPSSKQLPQSVDGKTVTANANSTTVAKQPTSNVALTRPKPVRTATSQSKIPKPVKHIPSDSNNLDPQLGPWRFANPKVDPIEDNSFIFGEHKSVKERRKYFSSSKFCRENFFYDKDVVYCMSFFSPHMDFNTFNLNIGPIRLNVYKHLNSDGHQPIRYMMRETDDEDAVMFVVEFDLLEDDDETVLAEQAKERERRKQT
What are the official names of this protein?
UPF0590 protein C594.01.
What is the protein family that this protein belongs to?
Belongs to the UPF0590 family.
Protein: NTM1_YEAST
Sequence: MDVPADSHIKYEDAIDYWTDVDATVDGVLGGYGEGTVVPTMDVLGSNNFLRKLKSRMLPQENNVKYAVDIGAGIGRVSKTMLHKHAAKIDLVEPVKPFIEQMHVELAELKDKGQIGQIYEVGMQDWTPDAGKYWLIWCQWCVGHLPDAELVAFLKRCIVGLQPNGTIVVKENNTPTDTDDFDETDSSVTRSDAKFRQIFEEAGLKLIASERQRGLPRELYPVRMYALKPMPN
What is the function of this protein?
Alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved.  Specifically catalyzes mono-, di- or tri-methylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif.  Responsible for the N-terminal methylation of the ribosomal proteins RPL12A, RPL12B, RPS25A and RPS25B.
What are the official names of this protein?
Alpha N-terminal protein methyltransferase 1, Translation associated element 1, X-Pro-Lys N-terminal protein methyltransferase 1, NTM1.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. NTM1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS1_PSEA8
Sequence: MLTIALSKGRILDDTLPLLAAAGIVPSENPDKSRKLIIPTSLSDVRLLIVRATDVPTYVEHGAADLGVAGKDVLMEYGGQGLYEPLDLRIANCKLMTAGAIGAPEPKGRLRVATKFVNVAKRYYAEQGRQVDVIKLYGSMELAPLVGLADKIIDVVDTGNTLRANGLEPQELIATISSRLVVNKASMKMQHGRIQSLIDTLRDAVEARHRH
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RMLB2_ECOLX
Sequence: MKILVTGGAGFIGSAVVRHIINNTQDSVINVDKLTYAGNLESLTEIENNERYKFEHADICDSVAIANIFAHHQPDAIMHLAAESHVDRSITGPADFIETNIVGTYILLEEARKYWLALSEDRKGAFRFHHISTDEVYGDLPHPDEVSSDTILPLFTEQTSYSPSSPYSASKASSDHLVRAWRRTYGLPTIVTNCSNNYGPYHFPEKLIPLIILNAIAGKLLPVYGNGEQIRDWLYVEDHARALYEVVTKGVPGETYNIGGHNERKNIDVVKTICRILDELIADKPDGIENFEQLIRYVSDRPGHDLRYAIDASKIKQDLGWVPQETFETGITKTIHWYLNNKEWWQRVMDGSYAGERLGLVE
What is the function of this protein?
Catalyzes the dehydration of dTDP-D-glucose to form dTDP-4-dehydro-6-deoxy-D-glucose via a three-step process involving oxidation, dehydration and reduction.  This reaction is a step in the biosynthesis of D-fucofuranose, a component of E. coli O52 O antigen.
What are the official names of this protein?
dTDP-glucose 4,6-dehydratase.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
Protein: NADD_ECOK1
Sequence: MKSLQALFGGTFDPVHYGHLKPVETLANLIGLTRVTIIPNNVPPHRPQPEANSMQRKHMLELAIADKPLFTLDERELKRNAPSYTAQTLKEWRQEQGPDVPLAFIIGQDSLLTFPTWYEYETILDNAHLIVCRRPGYPLEMAQPQYQQWLEDHLTHNPEDLHLQPAGKIYLAETPWFNISATIIRERLQNGESCEDLLPEPVLTYINQQGLYR
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: ACT2_HALRO
Sequence: MSDGEEDTTAIVCDNGSGLVKSGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDAGDGVSHNVPIYEGYALPHAIARLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFEQEMATAASSTSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVHRKCF
What is the function of this protein?
Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction.
What are the official names of this protein?
Actin, muscle 2/4/4A.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: HUB1_CANGA
Sequence: MIEVLVNDRLGKKIRVKCLEDDTVGDFKKVLSVQLGMQPSKIVLQKGGSVLKDHITLYDYEVHDNTNLELYYS
What are the official names of this protein?
Ubiquitin-like modifier HUB1.
Protein: PQQB_METNO
Sequence: MQAIILGSAAGGGVPQWNCRCPICAMAWAGDRRVLPRTQSSLAVSPDGERWLLVNASPDIRQQLLATPALHPRHGLRHTPIEAVLLTNGDVDHVAGLLTLRESQPFRLHATRNILESVSANRVFDVLAADLVARREVGLNETFEPVSGLAVTLFPVPGKVPLWLEEGTPEIGAETETTVGAMIEAGGRRLAYVPGCARVTEDLRHRLAGVDALLFDGTVLADDDMIRAGVGTKTGWRMGHVPMTGQGGSIAALAEVPIGRRIFVHINNTNPVLVENSEARRAVEAAGWDVGHDGMALRL
What is the function of this protein?
May be involved in the transport of PQQ or its precursor to the periplasm.
What are the official names of this protein?
Coenzyme PQQ synthesis protein B, Pyrroloquinoline quinone biosynthesis protein B.
What is the protein family that this protein belongs to?
Belongs to the PqqB family.
Protein: ATL48_ARATH
Sequence: MSSVEPDMEDLFQEKKRVRNPLVPLGALMTAGVLTAGLISFRRGNSQLGQVLMRARVVVQGATVALMVGTGYYYGDNPWKKLLLSEIHETEALSPKSSSAATLTLMNQKDPSSSSIVSVLCLVISGLALIIVFLGVLYLIFKFLRKSSTLFPIPHFNYNPDLFSFSSPQLQHLFFLHDSGLDQTAIDALPVFLYGNVTISLEQPFDCAVCLNEFSDTDKLRLLPVCSHAFHLHCIDTWLLSNSTCPLCRRSLSTSNVCYNHSETLVAPLSGHQQVDDGKASLAKRVFSVRLGRFKSTNESQSQRHDVKDEIGVRMPRRCYSMGTQQYLVCDQDFVVALSSSPREGNIGR
What are the official names of this protein?
RING-H2 finger protein ATL48, RING-type E3 ubiquitin transferase ATL48, YGHL1-C3HC4 RING fusion protein.
What is the protein family that this protein belongs to?
Belongs to the RING-type zinc finger family. ATL subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.