PharMolix/UniProtQA huggingface dataset:
Protein: HAT1_USTMA
Sequence: MKDSWSSNSTTSTAIRLVGSPYGTDSPFQPTFTYPIYGEAETIYGYEGLAIKLSVASGSLVPLLEVTYRAKNEATTAEIDDVEGKIKEFLAPDFLSTSSPSAMEEFETVVKADKEFRPLGDKVHSYTRGKVDKGKAKSSTASLASSTLSASDPNARVFEIYRSTWHTPGFREYHRRMQLFTLLFIEGASYIQEDETNWEFFTLYEKVSRDDKQTWHFMGYTSLYKFWCWPDSSRIRLSQFVILPPFQKQGHGGALYTTVYDQIRERANVTELTVEDPSEDFDRLRDGNDLRRLLAPGGFADSAKAQNKLHAPLDKEWIESQRLQHKLAPRQWSRVLEMVQLMNLDTTDHEQVKQYRLQVKARIYRQNKDILMQLEKQQQRSKLQETFEGVVEEYGDMVGVDVEDLLDDGPSGTGALYGADEEEDQEQGQGDRHYSNGNGPPRKMARLA
What is the function of this protein?
Catalytic component of the histone acetylase B (HAT-B) complex.  Acetylates 'Lys-12' of histone H4 which is required for telomeric silencing.  Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG.  Involved in DNA double-strand break repair.
What are the official names of this protein?
Histone acetyltransferase type B catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the HAT1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: END4_STAS1
Sequence: MLLGSHVSMNGKKMLEGSAEEAHKFGESTFMIYTGAPQNTRRKPIEELNIEKGHEIMKAHGLSNIVVHAPYIINIANTVKPHVFELGVEFLQSEIERTQALGAQDIVLHPGSHVGEGTDAGIKKIIEGLNEVLTNDNNVRIALETMAGKGSEVGRNFEELARIIDGVNHNDRLSVCFDTCHTHDAGYNVKEDFDGVLNEFDKIIGVDRIKVVHVNDSKNDIGAHKDRHENIGFGYIGFDALNYVVHHDTFKDIPKILETPYVGEDKKNKKPPYKLEIEMLKQQKFDEDLKNKILQQ
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: URGCP_BOVIN
Sequence: MASSGHSDLGEVTSEIKASERRTAVAIADLEWREMEGDDCEFHYGEGPNEAQDNDFPIEERSRLQEMLFLLGLETYQTQKLSLQDALQISSDSMKNWAPQTPKDLPWNFLRKLQALNAEARNTTMVLDLPLDTRPVEKESQMEEEIIYWDTAEDISADIYSFSELPTPDTPVNPLDLLCALLLSSDSFLQQEIVSKMSLCQFALPLILPDPENHYHTFLLWAMRGTVRTWGSQPPRVMGSFREDSMVLSRAPAFAFVRMEVSSNSKSQLLNDVLSPGHRQQDCFWHRDLNLGTNPREIADGLVEISWFLPSGREDLDIFPEPMAFLNLRGDIGSHWLQFKLLTEISSAIFILTDNISKKEYKLLSSMKGSATKYYFILSPYRGKRNTNLRFLNRLIPVLKMDHSHVLVKVSSTDSVGFVRRVRAIITHVTRSPCRRVSVEDMANAARKLGLKVDEDCEECQRAKDRMEQITRKIKDLDAYRRDELRLQGETWRKVAQVEKELCQIQWASDPPEKYRAELRHRLLELRMQQNDHDPSWGVQEFISGISSPSLGEKQYFLKWMEWGLARVAQPRPRPSPEMIFTLRPKHCGAVDFSEPFWPEPLGVEHFLREMGQFYEAESCLVEAGKLPAGQRRFAHFPGLALELLLKGLPLELIDGNTLSPALRWVTGLLKELHVRLERRSRLVVLSALGVPGTGKSTLLNTMFGLRFVTGRGRGPRGAFMQLIKVAESFSQDLGCDHILVIDSGGLIAGVRTEAGERFEREASLATLIMGLSNVTVVSLAETRNIPPAILHAFLRLEKTGHMPNYQFVHQNLHDVSALGSKPRDRRQLLDQPSDVGRATVQMEKQGDGIQTLADLAFWDPEKQHIWHIPGLWHGVPPMAAVNLAYSEAIFELKRCLLENIRNGLSNQNKNIQQLIELVRRL
What is the function of this protein?
May be involved in cell cycle progression through the regulation of cyclin D1 expression.
What are the official names of this protein?
Up-regulator of cell proliferation, HBV X protein up-regulated gene 4 protein homolog, HBxAg up-regulated gene 4 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=In epithelial cells localized predominantly in the cytoplasm and occasionally in nuclei.
Protein: RNC_ENT38
Sequence: MNPIVINRLQRKLGYTFQHHELLQQALTHRSASSKHNERLEFLGDSILSYVIANALYHRFPRVDEGDMSRMRATLVRGNTLAEIAREFELGECLRLGPGELKSGGFRRESILADTVEALIGGVFLDSDIQTVEQLILNWYQTRLDEISPGDKQKDPKTRLQEYLQGRHLPLPSYLVVQVRGEAHDQEFTIHCQVSGLSEPVVGTGSSRRKAEQAAAEQALKMLELE
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y828_GEOKA
Sequence: MNEKWIVERVEREGGRLWLYVNDAPVPLARVTPKRHMLVDSDALAFAYILETDDRFLYVMIPKPWWPELKAALDAKEPVWLRCGERTLELEQFHDELSYLLENIRGNANYGEALEQAVQDVFFEQ
What are the official names of this protein?
UPF0738 protein GK0828.
What is the protein family that this protein belongs to?
Belongs to the UPF0738 family.
Protein: UPP_BRUME
Sequence: MGVTVVSHPLVQHKLTIMRKKETSTASFRRLLKEISLLLCYEVTRNLELTTMSIETPLMPMEAPVLEGKKLVFASILRAGNGLLEGMLDLVPAARVAHIGLYRDHDTLQPIEYYFKAPEDIVNRLVIVVDPMLATANSAIAAIDKLKERGATNIRFLCLLAAPEGIERFTKAHPDVEVFTASIDECLDEKGYIVPGLGDAGDRMYGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: ALR_SHEAM
Sequence: MKPFPRAEISSRALKANLKRLRQIAPGSKVMAVVKANGYGHGLLNVAEVLTDAHSNADADGFGLARLEEALEVRAGGVSARLLLLEGFFRSEDLPLLVEHDIDTVVHHVSQLDMLESVSLSKPVTVWLKIDSGMHRLGFHASEFKDVYQRLQQNPNVAKPVHLMTHFSCADEPQKDFTATQMAHFNALTQGLPGDRTLANSAGVLYWPQSQADWIRPGIALYGVSPVAGDLGSNHGLEPAMELVSQLIAVREHSAGESVGYGAYWTASRDTRLGVVAIGYGDGYPRNAPEGTPVLVNGRRVPIVGRVSMDMLTVDLGPDAADKVGDRALLWGKELPVEEVAERIGTIAYELVTKLTPRVAVCLD
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: UL116_HCMVA
Sequence: MKRRRRWRGWLLFPALCFCLLCEAVETNATTVTSTTAAAATTNTTVATTGTTTTSPNVTSTTSNTVTTPTTVSSVSNLTSSTTSIPISTSTVSGTRNTGNNNTTTIGTNATSPSPSVSILTTVTPAATSTISVDGVVTASDYTPTFDDLENITTTRAPTRPPAQDLCSHNLSIILYEEESQSSVDIAVDEEEPELEDDDEYDELWFPLYFEAECNRNYTLHVNHSCDYSVRQSSVSFPPWRDIDSVTFVPRNLSNCSAHGLAVIVAGNQTWYVNPFSLAHLLDAIYNVLGIEDLSANFRRQLAPYRHTLIVPQT
What is the function of this protein?
Chaperone protein that cooperates with UL148 to regulate the abundance of gH complexes in virion (PubMed:33889136, PubMed:26937030).  First interactor of gH in the host endoplasmic reticulum, regulates the early folding steps of virion assembly.  Then, UL148 is recruited and favors the binding of gL (PubMed:34011552).
What are the official names of this protein?
Uncharacterized protein UL116.
What is the protein family that this protein belongs to?
Belongs to the HHV-5 UL116 protein family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum. Note=First localizes to the cellular site of virus assembly and then inserts into the virion envelope.
Protein: OTC_PYRAE
Sequence: MKHLLTLMEFAPHEVEYLLRVSREFKTRFLAGEIYTPLFPGRVLILYFEKHSTRTRLSLTSAAAQLGIQAVYTTPNELQIARGETVADTMRVISRYAAAVAARVYKHETLEEMARHSAIPVINALSDKHHPLQALADALTLWERAGRLHNVKIAFVGDVSNNVATSLAIIGAKLGWEVRLVGPKQLWNQRLVDELAEDAAKTGARIYFTDSINEVAGVDGVYTDVWVSMGFEKEAEERRRLLKPYQVNQRVMEIAGKKAVFLHCLPAHRGEEVTDDVIDGPQSAVWDQAENRMHTAKAVLAYLLK
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG172_VAR67
Sequence: MMIKWIISILTMSIMPVLVYSSSIFRFRSEDVELCYGNLYFDRIYNNVVNIKYIPEHIPYKYNFINRTFSVDELDNNVFFTHGYFLKHKYGSLNPSLIVSLSGNLKYNDIQCSVNVSCLIKNLATSISTILTSKHKTYSLHRSKCITIIGYDSIIWYKDINDKYNDIYDFTAICMLIASTLIVTIYVFKKIKMNS
What are the official names of this protein?
Protein A43.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG172 protein family.
Protein: LEUD_BURMS
Sequence: MEKFNVHTGVVAPLDRENVDTDAIIPKQFLKSIKRTGFGPNAFDEWRYLDHGEPGQDNSKRPLNPDFVLNQPRYQGASVLLARKNFGCGSSREHAPWALQQYGFRAIVAPSFADIFFNNCYKNGLLPIVLTEQQVDHLFNDTYAFNGYQLTIDLDAQVVRAPDGREYPFEITAFRKYCLLNGFDDIGLTLRHADKIRQFEAERLAKQPWLDNRLVG
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: FLGH_THEYD
Sequence: MRKLILISLCIFFLASCSELQEVRDIKNAGMPPKYYPEPPQTQVASEGSLWRNKASLYEDKKARRVNDLVTILINESTSAQKTASTTASRDSSTNYGLDTFFGMNTDFNIHNLPLINGFYKAGNVFSPSVKGSATSDFKGDGDTARTGKITGTITAKVVEVLPNGNLVIESRKEVIVNNEKEILVLRGIIRPDDISQSNTILSQYVADAQIYLVGEGTLGDKQSQGWLVRFLDKIWPF
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: CL029_PONAB
Sequence: MKRLGSVQRKMPCVFVTEVKEEPSSKREHQPFKVLATETISHKALDADIYSAIPTEKVDGTCCYVTTYKDQPYLWARLDRKPNKQAEKRFKNFLHSKENAKEFFWNVEEDFKPAPECWIPAKEIEQINGNPVPDENGHIPGWVPVEKNNKQYCWHSSVVNYEFEIALVLKHHPDDSGLLEISAVPLSDLLEQTLELVGTNINGNPYGLGSKKHPLHLLIPHGAFQIRNLPSLKHNDLLSWFEGCKEGKIEGIVWHCSDGCLIKVHRHHLGLCWPIPDTYMNSRPVIINMNLNKCDSAFDIKCLFNHFLKIDNQKFARLKDIIFDV
What are the official names of this protein?
Uncharacterized protein C12orf29 homolog.
Protein: RUVA_PROM1
Sequence: MISWLKGEKVHTWKISSRKGVVLNVGGVGYEIQLLPKQIDKAEVLNEFELWIHQIDREDGTSLYGFIEVNQRDLFREIISVNGIGPQIGMAMLEEFEVPQLVNAIENKESNLLTKTQGIGKRIAERLIVELRNKLQRFTDNDKTIHENKKGIEANQFSKYIDEIYLILNSLGYVDNEIKESIKIITINEKENSLLLNSSSAEEKAELMDKHLKEILMKLSEKTT
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: MEMB_METCA
Sequence: MSMLGERRRGLTDPEMAAVILKALPEAPLDGNNKMGYFVTPRWKRLTEYEALTVYAQPNADWIAGGLDWGDWTQKFHGGRPSWGNETTELRTVDWFKHRDPLRRWHAPYVKDKAEEWRYTDRFLQGYSADGQIRAMNPTWRDEFINRYWGAFLFNEYGLFNAHSQGAREALSDVTRVSLAFWGFDKIDIAQMIQLERGFLAKIVPGFDESTAVPKAEWTNGEVYKSARLAVEGLWQEVFDWNESAFSVHAVYDALFGQFVRREFFQRLAPRFGDNLTPFFINQAQTYFQIAKQGVQDLYYNCLGDDPEFSDYNRTVMRNWTGKWLEPTIAALRDFMGLFAKLPAGTTDKEEITASLYRVVDDWIEDYASRIDFKADRDQIVKAVLAGLK
What is the function of this protein?
Responsible for the initial oxygenation of methane to methanol in methanotrophs.  It also catalyzes the monohydroxylation of a variety of unactivated alkenes, alicyclic, aromatic and heterocyclic compounds.
What are the official names of this protein?
Methane monooxygenase component A beta chain, Methane hydroxylase.
Protein: MUKF_HISS2
Sequence: MLETSQTIPELVNWTREREFSLSLSTERLAFLLAIAIYNNERLDGEMLETDLIDIFRHISNTFEQSAETVSTRANNSINELVKQRFLNRFSSEFTEGLSIYRLTPLGVGVSDYYIRQREFSALRLSVQLSIVADEIQRASESAEEGGDEHYWRKNVFAPLKYSVAEIFDSIDLSQRMMDENQQHIKEEIAELLTKDWQTAIASCERLLDETSGNLRELQDTLNAAGDKLQSQLLRIQDCVIGHDNLYFVEQLIVDLQAKLDRIISWGQQAIDLWIGYDRHVHKFIRTAIDLDKNRVFSQRLRQSIHHYFDHPWFLWIAQAERLIDLREEELTLREEEALGELPEELQYESLADLHEQIVETMQSLLIEYRLQNTPIDLSEVLTAQLKQYPLANHFDIARIIIDQAVRLGLAQDDLNGIYPNWRSINENGAEVQAHVIDKY
What is the function of this protein?
Involved in chromosome condensation, segregation and cell cycle progression.  May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.  Not required for mini-F plasmid partitioning.  Probably acts via its interaction with MukB and MukE.  Overexpression results in anucleate cells.  It has a calcium binding activity.
What are the official names of this protein?
Chromosome partition protein MukF.
What is the protein family that this protein belongs to?
Belongs to the MukF family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: Y3707_DICDI
Sequence: MVNVFLIIIAVVIPALVVLASLYLIAYFQHPDDKNVAYFPKIIVILGLTLAATSILMLPLDVANDGGSGGFPMDILWIIIYIAVAVFAVVICPFAMFFYESEEADPGAGSQIAGAFKGTFAILFAFTALTIVLYVFFGVAEIPTIVVLGRFQVLNYPFMSDISNITYALPEIAAIIGGNDERIRFDPGNPDLLGDGSEYVEYRLDKEFLQFRVSIALFIITMVAFFGWLLFIIFGGIGLVALPFDMIGDFKNRPQRIPYDKYLERKKKIGERATELVEIGKTIQSRTSGGIMSKRDRKNYNRFRQAIFLLEEDYERLKISYKRQGGKVIFYYAQFFGGFVALGVSLGWLLHIIIYMITAPEPFHPFLNSLVIALNNAWGFLGVIVYGLLSFYLLFCVVKGNFKFGLRLFFLFPIHPMRVGNTMMNAFLFNVGLILITSVSITHFCTMAFSQFTSTTAINSLFETAVKNLKILKWFWVVYIFGVFVMAVLTAIFLFIKPKDKPAKIRV
What are the official names of this protein?
LIMR family protein DDB_G0283707.
What is the protein family that this protein belongs to?
Belongs to the LIMR family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ACB1_BPAC4
Sequence: MKLSDIDKGTYAAVKFDDSTLDMFQALQQIMELFNPVPRDKLHSTICFSRVKIPYIPLTEKMPIGSTHKLEVFEHNGKRALVVLLDSPYLESRHEYANILGATFDFPTYNPHVTLAYDIGAMEIPKHGVTGNPVVITHEYTEDLDLNWKP
What is the function of this protein?
Counteracts the host CBASS antiviral defense system.  Phosphodiesterase that enables metal-independent hydrolysis of the host cyclic di- and trinucleotide CBASS signals such as 3'3'-cGAMP, 3'3'cUA, and 3'3'3'-cAAA (PubMed:35395152).  Does not cleave cGG or cA4 (By similarity).  Besides evasion of the CBASS system, might also enable evasion of the type III CRISPR systems that use cA3 signals (By similarity).
What are the official names of this protein?
Anti-CBASS protein Acb1, Acb1, Gene product 57B, gp57B.
What is the protein family that this protein belongs to?
Belongs to the anti-CBASS protein Acb1 family.
Protein: MSTN1_XENLA
Sequence: MSQPQDAPVKKKRPPMKEEDLKGAKNKLAHQVPIKSKTYQVMKECEQSGTMAPSVFSQNKTGGETAFDKPKAGPAKSVFG
What are the official names of this protein?
Musculoskeletal embryonic nuclear protein 1.
What is the protein family that this protein belongs to?
Belongs to the MUSTANG family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MSRB2_RAT
Sequence: MARLLRALRGLPWLEAPGRARGCAGSGRGDTGSLIKSKLSLSKADWQKKLTPEQFYVTREKGTEAPFSGMYLKNKETGMYHCVCCDSPLFSSEKKYCSGTGWPSFSEAHGTKGSDESHTGILRRLDTSLGCPRMEVVCKQCEAHLGHVFPDGPDPTGQRFCINSVALKFKPSKP
What is the function of this protein?
Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine.  While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue.  Upon oxidative stress, may play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maintenance.
What are the official names of this protein?
Methionine-R-sulfoxide reductase B2, mitochondrial, MsrB2.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NAGB_ALKOO
Sequence: MIIHVEENYEAMSKKAALIVASQVVSNPAGVLGLATGSTPAGMYKELVDLFKEGIIDFSQITTFNLDEYYGLPKTNESSYYTYMMENLFNHINVPLERVHIPNGMAEDVEKECLAYEEKIRNAGGIDLQILGIGANGHIGFNEPDHKLSMKTHLVELTEKTIQDNSRFFQKEEDVPTKALSMGIGTILGAKKIILMANGKNKAEAIKEMTNGYLNPMVPASMIQAHPDVILIIDKEAASLL
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: RL14_STRA1
Sequence: MIQQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVKQATPGGAVKKGDVVKAVIVRTKTGARRPDGSYIKFDDNAAVIIRDDKTPRGTRIFGPVARELREGGYMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: FRDB_ECOL6
Sequence: MAEMKNLKIEVVRYNPEVDTAPHSAFYEVPYDATTSLLDALGYIKDNLAPDLSYRWSCRMAICGSCGMMVNNVPKLACKTFLRDYTDGMKVEALANFPIERDLVVDMTHFIESLEAIKPYIIGNSRTADQGTNIQTPAQMAKYHQFSGCINCGLCYAACPQFGLNPEFIGPAAITLAHRYNEDSRDHGKKERMAQLNSQNGVWSCTFVGYCSEVCPKHVDPAAAIQQGKVESSKDFLIATLKPR
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth.
What are the official names of this protein?
Fumarate reductase iron-sulfur subunit, Quinol-fumarate reductase iron-sulfur subunit, QFR iron-sulfur subunit.
What is the protein family that this protein belongs to?
Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CUTA_ECOHS
Sequence: MLDEKSSNTASVVVLCTAPDEATAQDLAAKVLAEKLAACATLIPGATSLYYWEGKLEQEYEVQMILKTTVSHQQALLECLKSHHPYQTPELLVLPVTHGDTDYLSWLNASLR
What is the function of this protein?
Involved in resistance toward heavy metals.
What are the official names of this protein?
Divalent-cation tolerance protein CutA.
What is the protein family that this protein belongs to?
Belongs to the CutA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_BORA1
Sequence: MKTFVAKPHEVTRDWFVIDAKGKVLGRVASEVARRLRGKHKPEFTPHVDTGDYIVIINAADIVVTGKKSQDKKYFRHTTYPGGIRETNFEKMQERFPGRAIQKAVKGMLPKGPLGYAMIKKLKVYAGAEHPHTAQQPKPLDL
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: PHK_MYCA1
Sequence: MSLETSTTTPAGSPLSDRELDLIDKYWRAANYLSVGQIYLLDNPLLKEPLSAEHVKPRLLGHWGTTPGLNLVYAHLNRIIRNRDADVIYVTGPGHGGPGLVANAYLEGTYSEVYTGIEEDAEGLRKLFRQFSFPGGIPSHVAAQTPGSIHEGGELGYALVHAYGAAFDNPYLVVACVIGDGEAETGPLAAGWHSNKFLNPVTDGAVLPILALNGYKIANPTVLARIPHTELEALLRGYGYRPITVAGDDPTDVHRQLAAALDEAFDDIAAIQGVARGGGEVQRPVWPMIVLRTPKGWTGPKVVDGKRVEGTWRSHQVPLAETHDNPEHRAQLEEWLRSYGPEQLFDDDGRLRAELRALAPTGDRRMSANPHANGGLLLHDLDLPDFRDYAVPVTRPGSVTHEATRVLGTFLRDVIARNKDRFRMMGPDETASNRLDAVYGATEKVWLSATEPDDEHLAPDGRVMEVLSEHLCQGWLEGYLLTGRHGLFNCYEAFVHIVDSMLNQHAKWLATSRELPWRRPIASLNYLLTSHVWRQDHNGASHQDPGFIDLVANKRAELTRVYLPPDGNTLLSVADHCLRSRDYINVIVAGKQPALAYLDMDAAIAHCTRGLGIWDWASTARSIGAEPDVVLACAGDIPTLETLAAADILRRELPDLAVRVVNVVDLMRLQPDSEHPHGLPDREFDALFTRDRPVIFAYHGYPWLIHRLTYRRANHAQLHVRGFKERGTTTTPFDMVMLNDLDRFHLVIDVLDRVEGLASRAAMLRQRMVDARLAARMYTREHGEDDPAIANWTWEPSERNSRSE
What are the official names of this protein?
Probable phosphoketolase.
What is the protein family that this protein belongs to?
Belongs to the XFP family.
Protein: HCAE_ECO57
Sequence: MTTPSDLNIYQLIDTQNGRVTPRIYTDPDIYQLELERIFGRCWLFLAHESQIPKPGDFFNTYMGEDAVVVVRQKDGSIKAFLNQCRHRAMRVSYADCGNTRAFTCPYHGWSYGINGELIDVPLEPRAYPQGLCKSHWGLNEVPCVESYKGLIFGNWDTSAPGLRDYLGDIAWYLDGMLDRREGGTEIVGGVQKWVINCNWKFPAEQFASDQYHALFSHASAVQVLGAKDDGSDKRLGDGQTARPVWETAKDALQFGQDGHGSGFFFTEKPDANVWVDGAVSSYYRETYAEAEQRLGEVRALRLAGHNNIFPTLSWLNGTATLRVWHPRGPDQVEVWAFCITDKAASDEVKAAFENSATRAFGPAGFLEQDDSENWCEIQKLLKGHRARNSKLCLEMGLGQEKRRDDGIPGITNYIFSETAARGMYQRWADLLSSESWQEVLDKTAAYQQEVMK
What is the function of this protein?
Part of the multicomponent 3-phenylpropionate dioxygenase.  Converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid-dihydrodiol (CI-dihydrodiol), respectively (By similarity).
What are the official names of this protein?
3-phenylpropionate/cinnamic acid dioxygenase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.
Protein: MYPC3_AMBME
Sequence: ARVKSENLLKKPVVKWFKGKWMDLGTKVGKHLQLQETYDRNTKIYTFEIHIIKAKTTYAGGYRCEAVSKDKFDSCNFNLNMHEASNAGEVDIRSAFRRTGDGKEEAGELDFSALLKKRDSFLLCESRQMKAEGHPRLMSGKSEGASPSEYEKIAFQYGITDLRGLLKRLKKMKKEEKKSTAFLKKLDPAYQVDKGQKIKLVVEVANPDAEVKWKKNGQDIKSSRTKYIFESIGNKRILTINHCSLADDAAYECVIGDEKCFTELFVKEPPYSSHAPLEDQMVMVGERVEFECEVSEEGAQVKWEKDGAELTREETFNYRFKKDGWQETYLLINEPTKEDSGHYTVKTNGWESVANLWVQEKSVLEVLQEVADLTVMARDQAVFKCEVSDENVKGVWVKNGKEVVPNDRITIRHIGRTHKLTIDNVVVAEDEGDYSFIPDGFAFNLSAKLKFLEIKIDFVPRQEPPKINLDVMGPAADTIVVVAGNKLRLDVPISGTPAPTVIWTKGNKVG
What is the function of this protein?
Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands.  In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase.  It may modulate muscle contraction or may play a more structural role (By similarity).
What are the official names of this protein?
Myosin-binding protein C, cardiac-type, Cardiac MyBP-C, C-protein, cardiac muscle isoform, CPRO axocard 1.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. MyBP family.
Protein: GLND_BURP1
Sequence: MSASVAEPPPALSRKAEFKAAKAELLARFKSANHVTPLMHALSRATDDALRSLWQECGLPATLALVAVGGFGRGELSPHSDVDILVLLPDAHASELDERIERFIGMAWDLGLEIGSSVRTVDQCIEEASHDVTVQTSLLEARRIVGSTALFERFMLRYREALDARAFFQAKVLEMRQRHAKFQDTPYSLEPNVKESPGGLRDLQTILWIARAAGFGSSWRELDTRGLITDREARELRRNEGFLKTLRARLHVIAGRRQDILVFDLQTQAAESFGYQPTSAKRASEQLMRRYYWAAKAVTQLATILIQNIEAQLFPATSGVTRVLSPGRFVEKQGMLEIAADDVFERHPDAILEAFLLYEATRGVKGLSARTLRALYNSRDVMNNAWRRDPRNRHTFMQILQQPEGITHAFRLMNQTSVLGRYLLNFRRIVGQMQHDLYHVYTVDQHILMVLRNIRRFAVAEHAHEYPFCSQLIVNFERPWVLYVAALFHDIAKGRGGDHSALGMADARRFCREHGIEGDDAALVVWLVQHHLTMSQVAQKQDTSDPVVIKRFAELVGSERRLTALYLLTVADIRGTSPKVWNTWKGKLLEDLYRATLAVLGGAQPDAHSELKTRQEEALALLRLETVPPDAHRALWDQLDVGYFLRHDAADIAWQTRVLYRHVAADTAIVRARPSPVGDALQVLVYVKDRSDLFAGICAYFDRNGLSVLDARVNTTRHGYALDNFIVTQTEHDVQYRDIANLVEQQLAARLAESAPLPEPSKGRLSRLSRTFPITPRVDLRADERGQYYILSVSANDRPGLLYSIARVLAEHRVGVHAARINTLGERVEDVFMLDGTGLSDNRLQIQVETELLRAIAV
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.