PharMolix/UniProtQA huggingface dataset:
Protein: NCB5R_KLULA
Sequence: MVPGKFIFTATFVLLCTIIAVVLEYQSKKDKPVLDKEKLQEFPLVAKTVLTHNTAIYRFGLPKSTQVLGLPIGQHISVQANINGKDILRSYTPTSLDSDAVGHFELLIKSYEKGNISKHFAQLNIGDKIKVRGPKGFYHYQPNMNEEIGMIAGGTGIAPMYQIMKSIFANDSDKTKVSLVYGNQTEEDILLKKELDAFVERKPDQFKVYYLLDKAPEAWTGGVGYITVDTMKERLPAPAEGVQLLVCGPPPMVSSIKRNAVTLGYEKAKPISKMGDQIFVF
What is the function of this protein?
NADH-dependent reductase for DPH3 and cytochrome b5.  Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2.  DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase, predominantly CBR1.  By reducing DPH3, also involved in the formation of the tRNA wobble base modification mcm5s 2U (5-methoxycarbonylmethyl-2-thiouridine), mediated by the elongator complex.  The cytochrome b5/NADH cytochrome b5 reductase electron transfer system supports the catalytic activity of several sterol biosynthetic enzymes.
What are the official names of this protein?
NADH-cytochrome b5 reductase 1, Microsomal cytochrome b reductase.
What is the protein family that this protein belongs to?
Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: DNAT_ECO81
Sequence: MSSRVLTPDVVGIDALVHDHQTVLAKAEGGVVAVFDNNAPAFYAVTPARLAELLALEEKLARPGSDVALDDQLYQEPQTAPVAVPMGKFAMYPDWQPDADFIRLAALWGVALREPVTAEELASFIAYWQAEGKVFHHVQWQQKLARSLQIGRASNGGLPKRDVNTVSEPDSQIPPGFRG
What is the function of this protein?
This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response.  It forms, in concert with DnaB protein and other prepriming proteins DnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'.
What are the official names of this protein?
Primosomal protein 1, Primosomal protein I.
What is the protein family that this protein belongs to?
Belongs to the DnaT family.
Protein: PYRG2_XENLA
Sequence: MKYILVTGGVISGVGKGIIASSIGTILKSCGLRVTAIKIDPYINIDAGTFSPYEHGEVFVLNDGGEVDLDLGNYERFLDINLYKDNNITTGKIYQQVINRERRGDYLGKTVQVVPHITDAIQEWVLNQAKVPVDRDQKEPQICVIELGGTIGDIEGMPFIEAFRQFQFKAKRENFCNIHVSLVPQPSATGEQKTKPTQNSVRALRGLGLSPDLIVCRSAKPIEMAVKQKISMFCHVEPEQVIFVHDVSSTYRVPILLQEQGIIKYFKQRLSIPIEDQPSTQLFKWKRMADRYERLLKTCSIALVGKYTKLSDCYTSVFKALEHSALAINHKLNLMYIDSADLEPSMKAQDPVKYHKAWEELCKAEGILVPGGFGLRGTEGKIQAITWARERKIPFLGICLGMQLAVVEFARNILKMTDANSTEFDPNTKNPAVIDMPEHHPGDMGGTMRLGSRKTVFKTSESVVKKLYDNQDFVEERHRHRYEVNPELVQQFEEKGLKFVGQDNEGQRMEIIELEGHPYFVGVQFHPEFCSRPMKPSPPYLGFMLAASGKLNTYVQNGCKLSPRNSYSEHSDESSSDS
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides (By similarity).
What are the official names of this protein?
CTP synthase 2, CTP synthetase 2, UTP--ammonia ligase 2.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: CE034_RAT
Sequence: MGTAAEVRMVLYEDDSVQVNYADGSTLQLSPCGSEFLFEKAPPPSTHPLEQPERIRQRTHFVISNYREQLQRALDFRNSSATCPFLSESIIPSERKKRVFIDFSEVEWPSPDRDDCITYSESGIVKITSLDGHAYLCLPRSQHEFTVHFLCKVSQKPDSSVMPPETKNRVPKEELVGKTRNVCRSGRLSGQRLRNKENEPPRQLLTSKNASANIHCVSETEGREELPSPGTKRRYVHVWVKQSWSAASCPEEWKYPLSLGLRFYNKVPAASAADAEVPVSGIVTSDNPEERGTGVSVLPRALLLSCSAPHMHRWNFCDSLLQRQSDAEEYSYPELIKVVWYKGVTYRLTHKNVNSIEIFPGDGSVFKSEGTHFGNYFTYSSQDNSGKREEKTYSVNNLPPDRPGNLYSVRSLIKQATRILQHCAKIRLSLSHNYRVCCWRMAPGVNVSSILPVLLKESLIPGVGRFLAYSDDKVHAVFLDGVTLTLNWDLSSSAEKTQVDQGLRLRWCRLTFPDGQDQLIQTEHPGVYERYVTSVVTWCRRLTQTSSRHVSPRLSPVPEENWSVASELEKIQKFNWLLENSGVLNLTSGKKNEQCSSDHCKPGSSETLPEATNEESVSVALKRTSEVLQDIDYLLSLTRK
What are the official names of this protein?
Uncharacterized protein C5orf34 homolog.
Protein: ATPL_BUCA5
Sequence: MENLNVDMLYIAVAIMVGLASIGAAIGIGILGGKFLEGAARQPDLVPLLRTQFFVVMGLVDAIPMIAVGLGLYMLFAIS
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BAME_BUCAP
Sequence: MSNQIVLGMLMIFLFSSCSVLENKHYVLNNNLNESYFNLNKFKKNYKGMTKEQIIYIFGNPIISDSFNDVFHYIICAEENGFGCHQKILNIFFKKNKVSKLDIR
What is the function of this protein?
Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
What are the official names of this protein?
Outer membrane protein assembly factor BamE.
What is the protein family that this protein belongs to?
Belongs to the BamE family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: TSAC_PSESM
Sequence: MVSSWRVQQAAQNIRAGAVIAYPTEAVWGLGCDPWDEEAVYRLLAIKLRPVEKGLILIADNIRQFDFLFEDFPELWLDRMASTWPGPNTWLVPHQNLLPEWITGIHETVALRVTDHPTVRELCALVGPLISTSANPAGRPAARSRLRVEQYFRGQINGVLGGSLGGRRNPSVIRDIATGQVMRAG
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LST8_ORYSJ
Sequence: MAQPSVILATASYDHSIKFWEAKSGRCYRTLQHTESHINRLEITPDKRFLAAAGNPHIRLFDINSNSNHPVISYDSHTSNVMAVGFHCDGNWMYSGSEDGTVRIWDLRTATCQREYESRAAVNTVVLHPNQKELISGDQNGNIRVWDLAANSCSCELVPEVDTAVRSLTVMWDGSMVVAANNRGTCYVWRLLKGTQTITCFEPLHKLQAHDGYILKCLLSPEFCDPNRYLATASSDHTVKIWNVDGFKLEKTLVGHQRWVWDCVFSVDGAYLITASSDTTARLWTMSTGEAIRVYTSHHKPVVCCALHDGAESAPS
What is the function of this protein?
Component of TORC1 complex, which is an essential cell growth regulator that controls plant development.  Acts by activating transcription, protein synthesis and ribosome biogenesis, and inhibiting mRNA degradation and autophagy.
What are the official names of this protein?
Target of rapamycin complex subunit LST8, TORC subunit LST8, Lethal with SEC13 protein 8 homolog, WD40 repeat-containing protein 81, OsWD40-81.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LST8 family.
Protein: NOP12_KLULA
Sequence: MSALNNLFGNSKSDAAGTSSIAALFSKPNHVDERKVKSKARTVLTEPEQDKDEQEEENVQESASTVSEGVEKEQEEQEEQPKKKKKKTKKNDEENDNLEVQYYSKVLGDSKSKDEPKDEPKDDSSDSDNEDEATAVDKSSITGTESESAKVINLKEKELAKAERTIFIGNVPNEVITSKKVYKEFKKLLSKDPRSENDDHDDGEEDEEEEESKTKDVKFNVESIRFRSIAFEEALPRKVAFVHQKLHKSRDSINAYAVYGSSNPVKIMCQYLNGKVFNDHHLRVDSVTHPSPHDKRRSVFVGNLDFEEVEESLWKHFEPCGDIEYVRIIRDSKTNMGKGFAYVQFKDFQSVSKALLLHEKKIHEGKKARKLRISRCKNMRKAQGNQSSLQNNKLNDQQRTKLGRAKKVLGKADRAKLGEELTIEGLRASKGETTPVLKRTKNRSKTGRVTKRSIAFKKQNAQ
What is the function of this protein?
Involved in pre-25S rRNA processing.
What are the official names of this protein?
Nucleolar protein 12.
What is the protein family that this protein belongs to?
Belongs to the RRM RBM34 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: FTSH_SALTI
Sequence: MAKNLILWLVIAVVLMSVFQSFGPSESNGRKVDYSTFLQEVNQDQVREARINGREINVTKKDSNRYTTYIPINDPKLLDNLLTKNVKVVGEPPEEPSLLASIFISWFPMLLLIGVWIFFMRQMQGGGGKGAMSFGKSKARMLTEDQIKTTFADVAGCDEAKEEVAELVEYLREPSRFQKLGGKIPKGVLMVGPPGTGKTLLAKAIAGEAKVPFFTISGSDFVEMFVGVGASRVRDMFEQAKKAAPCIIFIDEIDAVGRQRGAGLGGGHDEREQTLNQMLVEMDGFEGNEGIIVIAATNRPDVLDPALLRPGRFDRQVVVGLPDVRGREQILKVHMRRVPLATDIDAAIIARGTPGFSGADLANLVNEAALFAARGNKRVVSMVEFEKAKDKIMMGAERRSMVMTEAQKESTAYHEAGHAIIGRLVPEHDPVHKVTIIPRGRALGVTFFLPEGDAISASRQKLESQISTLYGGRLAEEIIYGVEHVSTGASNDIKVATNLARNMVTQWGFSEKLGPLLYAEEEGEVFLGRSVAKAKHMSDETARIIDQEVKALIERNYNRARQILTDNMDILHAMKDALMKYETIDAPQIDDLMARREVRPPAGWEDPNGTNNSDSNGTPQAPRPVDEPRTPNPGNTMSEQLGDK
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: GEP3_KLULA
Sequence: MKSRLQAFKQFTRFVSCKSCGVELQSKNPSVTGYYKPPRAVRKDAGTIEDLKYLMFTQELQLKKHEIGLLDPDTDPDYKEPIPKRLVCKRCVDAISHNRYNSSDFPIHSFNDIKGALPHAANVYHVVSLSDFPLSLDKTILAEKNNRNYLLLSKADQITYKSSMLPHKGSAFFAEFCRRHIGVHVKKVVLFSNPRNWNIPSVINALAKRCYLLGNPNVGKTSLINSLLHEKSTSFQAQLDKRGNVIGPPKGHEQIQSTRRRAIFNEGGVSHIPNFTRTMQTYLIEDKVVNDLPGYTMDPTKVSDLANYIEKETLDNIRKTSKFKIDKLIKQNYTSLTGSKTGKCLSFGGIFHLVPPNSTINQVVNYIPLPEHEFSNVEKAVSLSLEVLQSENHSLRQFFALKKPFTDIKMFDRHVIPPFNGAIEIVLKDIGYFQVKPTGKYGFNGLYELWVPKGIRVCIREPLSKLISKSYEKYIESGDIADVCPTDRPLISDTYIMNHTEEDTFARMREMYINRTSKDILSRRLLQKDPNDIVGTLQSPPSNLYWYYKW
What is the function of this protein?
May be involved in the mitochondrial lipid metabolism.
What are the official names of this protein?
Genetic interactor of prohibitins 3, mitochondrial, Found in mitochondrial proteome protein 38.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. GEP3 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RIMP_STAAN
Sequence: MSKITEQVEVIVQPIMEDLNFELVDVEYVKEGRDHFLRISIDKEGGVDLNDCTLASEKISEAMDANDPIPEMYYLDVASPGAERPIKKEQDFQNAITKPVFVSLYVPIEGEKEWLGILQEVNNETIVVQVKIKARTKDIEIPRDKIAKARHAVMI
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y22B_METJA
Sequence: MGTMNVVGLAIYLYAGFLSFIFGFISLYAFIKYSKLERKNKEIIYVYVDNLKNFSPYMFYSILLTFTIVFVIFALFICFVFNFDLYLGLTMLFSYFLIIYLFCFKKYRVEIYKDGFYGVFQN
What are the official names of this protein?
Uncharacterized protein MJ0226.2.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PDXA_XYLFA
Sequence: MLHPALALVPGEPAGVGPELCVRLVQQPRQDCRLVAFADPATLQAAAAALDLPLRLLPPEALAERPGDLPIQAQCHVHPTRFGHPDPANAPAVIAALCEAASDCVHGALHGIVTGPVHKAVINQSGIHYTGTTELLAAQAECDVVMMLANPHLRVALVTTHLPLRDVPDVITAALLERCLRIVNTAMCGDFGIATPRIAVLGLNPHAGEGGYLGREELDVVIPVLQRLRAEGMVLLGPLSADTAFLPTKLIGYDAVVAMYHDQGLPVLKHSGFEQAVNITLGLPYPRVAVDHGTALDLAGRGVADPSSLFAATALCARLAVSRALLSVRS
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIBF_ECOL6
Sequence: MKLVGSYTSPFVRKLSILLLEKGITFEFINELPYNADNGVAQFNPLGKVPVLVTEEGECWFDSPIIAEYIELMNVAPAMLPRDPLESLRVRKIEALADGIMDAGLVSVREQARPAAQQSEDELLRQREKINRSLDVLEGYLVDGTLKTDTVNLATIAIACAVGYLNFRRVAPGWCVDRPHLVKLVENLFSRESFARTEPPKA
What are the official names of this protein?
Uncharacterized GST-like protein YibF.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. HSP26 family.
Protein: GTT3_YEAST
Sequence: MPTKSTFSRWKKADLIDLANKLEIDGFPNYAKKSDMIDYLESHLNHLEKPVDFKDDYPELRSFYESMTVDQSKDERNEYGSGSGNGSGSGSCDTATNDSDLEKAYIKEDDDEKPQSGDETSATKPLSSRNANSNAKTNFNLLDFSTDNDSSTSAFTKFKFNFQEYLSDIRYQTQKLNENVQDYLSTISAVDTIFSLLEFSFLVRNILAAGQPTSSSSLASSLEAAVAAHNKYQYTLDFCLPILTWLLFFRGIPTLVSYYINFIRYDLNIELDPMTFNLTKFLISLAIFKTCNNKNIDFHSFRCVNQLWTQLCTVNRSLGMVPLVFSMVSCLLTLYVL
What are the official names of this protein?
Glutathione transferase 3.
Protein: KIF4_DICDI
Sequence: MDNNNNNNNNNNDKNDKNELNKIKVAIRVRPLNSRELGIDQKIPWSISKDTISLSQNPNINFTYDYVFGIDSNTIDVYNAIAKSIVNSSLNGINGTIFAYGQTSSGKTFSMRGTESIPGIIKLSIKDIFKSIEDSILEKDYLLKVSYLEIYNEEIKDLLNPTISNKKKLKIHEDIYKGVVVANLKEEIVISPDQIFALMNFGEERRHIGSTMMNDSSSRSHTIFRMQIQSTCKQNGTIQMSTLTLVDLAGSERVSSTGAEGVRLKEGTHINKSLMTLSKVISKLSEEKTQQHVPYRDSKLTRILQPSLGGNSKTAILCTITPATTHQEESISTLQFAKRAKRVKTNYKINQVADANTMLKKYESEILELQNQLVKSEEINSLLRNTISTQEISSNNFKLGMKRFNDAIIGGSLINENKKKKKRRNTLDPSYLLKDKIIKKKIRKSENQKIKKIKNSENNISSSSSNSSGEEDDDDKDDENNYSINQDDKDDSNYEDDDDEDEDDDEESDTDNEDDEDNDEDNDDDDDDDDEFKDNLNLIEPLDDETIKKIKDLDDSLGISGQVKVKREDLDLIYEELEENKKLIEEYESTLELLNNQLDEKEIEHKELLIIIDQWEQECTNRENQNQELLEIDQQSKQSIQQLNDKLLETKQQSKQSIDQLNLQLIDIESESSKNKKSFENVLGVFEKSYRLAERLEDKYFTKEIESKKQIETLANSYLQLETTYQQQLNINQQSQQKIQSLNNDIEQFKLVWVPLKDQVNGYFQENQMFKQYIIELEEKYNTLIDLQKEVEQNYLTNTLEQQRNDQYQIEINQLTTEYNNQIQQLESTNQKLQTQLYNLLANATQSTQTLEQQLQTSKQEIDTLTNEIEQLKNQYDIIRVDNDNLSKESLELKQILLSKTQQLEEQLSLAQQQKGNIEIIQQLESIIVDNQQSIDQLKIEFDQSQQDNQSIKQSYNQLESTLTLAQSENQRLLTENKQFITSLNEIKSLFNSIQQQKETIQLEFNQRLQSWSLDSEKYKEIISTLEQSNQKSIESYESKSLEFQEKENQFDSLLTNYNQLFSKYNDLATSNESNRLEFDQFKKDSNQSIQSLESLERSLKSENDNLLQQSNLLKSQLESIEKQKQDQLIPIQLELESKKCELSKLSSQFSEQTKQVTQLLISVDQYKISTNKLESQISDRNEEINNLKLKAIEINALKEENISLKDQLTKLKKAPKSQTDREKDMIKKELEKLREKFNAIDAKLKQAIQDKQTIQSEKQSLEREIKDLKRSHTSTETELDKLKKTHLAADVKSKDFIALNKSVEILTKSQEQLKSTIIELESDLSKKNIELEKKQEELVTLNQDKLEKEKKTNQLESDHSSATIKLENYENQITQLTSEIIDLKSKFQEFKSESESNIKQQEINLKESNDLNQQLTNDKFELTKQLSDLKVEFDKSKQLWSTRSSESNDTIKELQESIISKDKERQLTSEQLVKLTDQINLKTWEYNDLNSQCQQLTKTLQNVKSSNEQQEQSIVSLESQTSAKIKSLELEISQIQENHRLEVLELNRCKNQLSEKQTLMEQDNIQLNERIIQLLHQKTKHENEILSMESNIIDLENQTKELKSKIETAQQDFEIEKNYHTGLNETNTTTIKTMNEELTRSNQTIQQLLFKISKLEQTSLQTQQQQELQQATISAQQQKQQQLADDQEKQQLYQKIKLIEKELESTKQKNLYITEQFTLKESEYLDTITDYVCKEKEFEKSKASLKTSATKIQALNDIIKKLQEEKPQQQPVVKVSSSQVVNQNGQPIKSILKKPKLVIIPREQLQQPPQFKELTLSTLNSNDSNCEPESVSASSTLTSLQSISKYIGKRSEQTTLEHDLTSSTLNLPLQQQNKKVRLVITKNNKTSTDNLTTTSTSLKSKSSSNGENKENQNNNIIIKNN
What is the function of this protein?
Microtubule-associated force-producing protein that plays a role in organelle transport.  Its motor activity is directed toward the microtubule's plus end (By similarity).  Cooperates with dynein in organizing spindle assembly during cell division.
What are the official names of this protein?
Kinesin-related protein 4, Kinesin family member 4, Kinesin-7.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: Y1117_LACJO
Sequence: MISIVKSKSFGLAAVMTLICSVAGIFLAKLPYVNLIGALVIALLLGISLQVLPVGVREEAAPGIGFISNKFLRLGIILLGFRLNLTKLADAGIKTILVAMLGVSGTIVLTYWLSKKFGAEDELAVLSACGCGICGAAAVMGVSPQIESRDEERKRENEVLAVAVVCVMGTVFTLLEIVIKPMLGLTDSQFGIVAGGSLHEIAHAIAAGSAFGEASLDSALIMKLSRVLLLAPVALIIGYWYQRRLVKESAQDHTQAPKKLPIPWFLGGFILTSILGTFLPFPPVVLDGLVQAAYVFLGMAMAALGISVNFSVIFKRGGTVFGAAAISSTCLMIFMIIMSKLFF
What are the official names of this protein?
UPF0324 membrane protein LJ_1117.
What is the protein family that this protein belongs to?
Belongs to the UPF0324 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AGRA3_DANRE
Sequence: MSVLCVLLLAFVLPLRGSSSAGSTECKTYDERSRSAGKSSPSGATLDRKVVCSNMEFRQVPSPDTFPNRTVSLILSNNKIQELLNGSFVGLSSLERLDIKNNIITHIEPGAFYGLFSLKRLDLSKNLIGCLHVDVFKGLTNLVKLNLSENKFSSLSQGIFDSLGSLKILEFDSPYLLCDCNLQWLVVWIKEKAIGVKETRCSFPRSLQGQLITTLRAETLTCDAPLELPSFQMTPSQHQIVFQGDSLPFQCMASFVDEDMQVLWYQDGKMVEPDATQGIYIEKSMVQNCSLIASALTISNIQPGFTGNWECRVRTSRGNNTRTVHIVVLESSAKYCLPDRVSNNKGEYRWPRTLAGITAYLPCKRQVTGAGIYSGSSAEDRRAWRRCDRGGQWAEDDYSRCEYMKDVTRVLYIINQMPLNLTNVVQTAQQLLAYTAEAPNFSDKVDVIFVAEMIEKIGKFAEKYKELGDVMVDISSNLLLADERVLWMAQREARACSRMVESLQRIALLRVSNGALAYSTNSPNIALEAHAIKASSFNGMTCTLFQKLSPERTVMAHHGEISPERQLSFKCNVTSNLSALALKNTIVEASLQLPPTLFSSLGSSGQAEEAVYKLHLLAFRNGKLFPPTGNSSILSDGSKRRSVVTPVMITKIEGFPLRDLLSPVNVTLRRFLQGSDAVPAFWNFSLQGGQGGWQSDGCRILHQDDNFTTVSCHSLNSYAVLMDLNRTGYNVFIFRPLHPVIYSTALVLVLCLLSVIVSYIYHHKSVRISKKCWHMLVNLCLHILLTCAVFVGGINQTYNASVCQAMGIVLHYSTLATALWSGVTARNIYKQVTRKAKRYEELDEPPPPPRPMLRFYLIGGGIPIIVCGITAAANIKNYGSQVNAPYCWMAWEPSLGAFYGPAAFIVFVDCMYFLSILIQLRRHPERRFELKEQSEEQQHLSVTEATEITPVHLESSPTAQPVPMSALENEHTFVSQLMGVAGSLTLYAALWVFGALAISQEHPADLVFACLFGALALGLGAFLVAHHCVNRQDMRRHWSQACCLIRRNYAVQVDSLLLPIAGSSGSVMTSRGNGEATKCPASSAESSCTNKSAPSLRNSTQGCKLTNLQVEAAQCKVVAPSTANGTAVLDNSLTEHSVDNEIKMHVAPIEIQYRPSSVNNNNLPGNANITGHPGRHHKNRSRAHRASRLTVLREYSYDVPTSVEGSVQSVPNKRHHHESLHARNSRRAAYLAYRERQQSQLQQDSSDAASTSVPRRSRHFSKGTRIGNGFGHGISNGGLLDGSEADVTNQTKECPKQTLTVELEVQPKSYGLNLACQNGSAKDSERLNVESSGNVKTGLWKHETTV
What is the function of this protein?
Orphan receptor that acts as a critical modulator of planar cell polarity during gastrulation.  Controls the localization of dishevelled.
What are the official names of this protein?
Adhesion G protein-coupled receptor A3, G-protein coupled receptor 125.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RNPH_SALG2
Sequence: MRPAGRSANQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTASIEEGVPRFLKGQGQGWITAEYGMLPRATHTRNAREAAKGKQGGRTMEIQRLIARALRAAVDLKTLGEFTITLDCDVIQADGGTRTASITGACVALADALNKLVANGKLKTNPMKGMVAAVSVGIVNGEAICDLEYVEDSAAETDMNVVMTEDGRIIEVQGTAEGEPFSHEELLTLLSLARGGIESIVATQKAALEN
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: TEX14_RAT
Sequence: MSRAVHFPVPCPVLLGTLTDDSLEAQLHEYAKQGNYVKVKKILKKGVCVDAVNTLGQSALFVAALLGYVKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKVLTAGGDLRLHDEKGRNPQAWALAAGKDRSTQMVEFMQRCASHMKAVIQGFSYDLLKKIDSPQRLIGSPPWFGGLIQGSPNSSPNRQPKPGIISAQNIYSFGFGKFYLTSGMQLTYPGSLPVIGEKEVIQADDEPTFSFFSGPYMVMTNLVWNRSRVTVKELNLPTHPHCSRLRLADLLIAEQEHSSNLRHPSLLQLMAVCLSRDLEKIRLVYERITVGTLFSVLHERRSQFPVLHMEMIVHLLLQIADALIYLHSRGFIHRSLSSYAVHIVSAGEARLTNLEYMMESQDSGAHRDMTRVPLPAQLYNWAAPEVVLQKTATVKSDIYSFSMIIQEILTDNIPWNGLDGSLVKETIALGNYLEADVRLPEPYYDIVKSGIHAKQKNRTMNLQDIRYILKNDLKEFIGAQKTQTTESPRGQRYEPHPDINICLGLTSEYQKDPPDLDIKELKETGSQPHSPTDHSFLTEKTLAPQTLDSSLSAQEPDNPNVPSASRLAEEVRSPTPSEASLYSFEINEIYSGCLTLGTDKEEECPGTASSPEGDKANQVDELPSLEEELDKMERELHCFCEEDKSFSDVDTDLSFEDGDWQSDSLSSLSLPEPTREAKGKTSSWSKTDEYVSKCVLNLKISQVMMQQSAEWLRKLEQEVDELEWAQKELDNQCRSLWDASLRFANTKFLSAVGPPSLTYLPPVMQLSEPKQPENGGNWLTLARPPGNERDFQEGNFSKKSEKLSACDWNPFTQASEESRGYCSEPNNQPPTLCGPGKQNTGEQLPSTEEAKESLERNTNQNIRRMESVSSEVCDTKSRNNEDAGEARSKWRLAVKEMAEKAVSGQLLVPPWNLQSSFESKVENESTPLPRPPIRGPESTDWQYILEYQREKDELKGNMKFGKMENSDCDKNKHSSWTGLQRFTSIIYPFFRNHEQPEHNEASQASCDTXCGEKFYSTSSPIEDDFERIQSSFAQPQGYVEENFQIREIFGKNAEILTKPQFQAVQCAEDEQEETLEETPKELKEKNISLTDIQDLSSITYEQDGCFKETSCKTPKLKHAPTSASTPLSPESISSAASHYEDCLENTFHVKRGSTFCWNGQEAMRTLSTKFTTVRERAKSLESLLASSKTLPAKLTDPKRLCMFGGACSSNISTAFVTSTHSTKRKSLPGELAEATSQHHIDELPPPAQELLDEIEQLKQQQVSSMVSLENTAHDLNVTENDKKHLEEQETNSSKDSSFLSSREIQDLEDTERAHSSLDEDLERLLQLPEENMTLLDPTKGSTREKKTKDQDMVEQKRKKKEGIKPERRKSDSFLGTLEEDELKPCFWKRLGWSEPSRIIVLDQSDLSD
What is the function of this protein?
Required both for the formation of intercellular bridges during meiosis and for kinetochore-microtubule attachment during mitosis.  Intercellular bridges are evolutionarily conserved structures that connect differentiating germ cells and are required for spermatogenesis and male fertility.  Acts by promoting the conversion of midbodies into intercellular bridges via its interaction with CEP55: interaction with CEP55 inhibits the interaction between CEP55 and PDCD6IP/ALIX and TSG101, blocking cell abscission and leading to transform midbodies into intercellular bridges.  Also plays a role during mitosis: recruited to kinetochores by PLK1 during early mitosis and regulates the maturation of the outer kinetochores and microtubule attachment.  Has no protein kinase activity in vitro (By similarity).
What are the official names of this protein?
Inactive serine/threonine-protein kinase TEX14, Testis-expressed sequence 14, Testis-expressed sequence 14 protein.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily.
What are the subcellular locations of this protein?
Cytoplasm. Midbody. Chromosome, centromere, kinetochore. Note=Detected in the intercellular bridges that connect male germ cell daughter cells after cell division.
Protein: NANE_LACPL
Sequence: MKNTFLNTVKGSLIISCQALPNEPLHSSFIMSRMALAAKGAGAAGIRANSVVDIQAIQDEVDLPLIGLSKVDYPDSPVYITPTIKEMRAVAATGCAVVACDVTGQPRPNGEKLAEIVATMRTEFPDTLLMADTDTIENVKVADKLGFDIIGTTMHGYTPATTGANIADNDFAYLKEVLQATSRPVIAEGKVDTPEKMKRCLDLGCHAVVVGGAITRPLEIAQRFISAL
What is the function of this protein?
Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).
What are the official names of this protein?
Putative N-acetylmannosamine-6-phosphate 2-epimerase, ManNAc-6-P epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanE family.
Protein: RISB_STAAM
Sequence: MNFEGKLIGKDLKVAIVVSRFNDFITGRLLEGAKDTLIRHDVNEDNIDVAFVPGAFEIPLVAKKLASSGNYDAIITLGCVIRGATSHYDYVCNEVAKGVSKVNDQTNVPVIFGILTTESIEQAVERAGTKAGNKGAEAAVSAIEMANLLKSIKA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: CYA1_RHIME
Sequence: MLQRSESGFKDIESMQDSNADKPSRTWTSSLRSLLGLVMVAMLIVVSATLVGLDYRRARSAAIAGAEDNMDAFVGRLVDRLGALSGDTSALVSLVASVANSFLVPPPERMNDKVAVLREGIARSPHIDGVYVGYPSGAFFHVVDLDSAAWRMALDAPRGAAIAVRSMERNDQGKPFDRILFLDASGLQFAERHAASNGFDPRTRPWYRAAVNGKAPVAIGPYEMATTGNLGMTISQAHRGNPQIVIGADVVLDTITDFLSRERLTDDSVSFVLDAVGRPIIHSDSTMMRRIMASKGRDRPVATPQEDGLIESIRRNPPPAGKATLVEVGNRTYLVTVAPLESALLLSGHRVVVAAPLDELLAAANETLVQGLAVSGAVVVVAVLLALVLAHLITKSLNQLTDSANRLQDLDFATPIDVSSHVAEISTLNGAMNRARDAIFTFALYVPKELVRKGIESGHFGGRAAWRQEVTAMFTDIYDFTTISEGRSPEEVVAMLSEYFDLFSEVVAAHDGTIIQFHGDSVFAMWNAPVADTRHAEHACRCALAVEERLEAFNSAQRASGLPEFRTRFGIHTGTAVVGSVGAKERLQYTAMGDTVNVASRLEGMNKDYGTSVLASGAVVAQCKDMVKFRPLGTAKAKGRSTALDIYEVVGVVRAVNTTEAGTAA
What is the function of this protein?
Plays essential roles in regulation of cellular metabolism by catalyzing the synthesis of a second messenger, cAMP.
What are the official names of this protein?
Adenylate cyclase 1, ATP pyrophosphate-lyase 1, Adenylyl cyclase 1.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL10E_METM6
Sequence: MALRPARCYRTTERRSYTRKEYVRAVPQPKVVHYVMGNSSVEFPVEVQLISKSDILIRHNALESSRIAGNKYILRECGRTGYLFNIRVYPHEILRENKMAAGAGADRISDGMRLSFGKAVGTAAKVKKGQEIITIGVNPEKFYAAKEALRRCSMKLPTACKIVVTKGQDLIRD
What are the official names of this protein?
50S ribosomal protein L10e.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.