PharMolix/UniProtQA huggingface dataset:
Protein: APTA_EMENI
Sequence: MKDNTHSTTLIFFGNEFPNDDLKGLFRCLLRLSKDRRFRQLAAFLEESTLVLKKEVAALPQPLRDLVPHFHTVLPLAELGDFRQGPLGAAMESALLTVLELGMFIGHYEAEGRDWNLLEHNTTLAGLSIGLLAAAGVALSTNLAEVAQNGAECVRVSFRLGVYVSEISRKLEAPQADGTLLSWAHVVTGETKSAIQDELSKYNSESGTPELLKVFISAADKTSVSVSGPPSRMKACFSSSHLLRYSKSFALPVYDGLCHASHLYNEDSINTVINSAESVIPVSRPVQLSLHSSNTGQPFPAATAHELFQAIGKELLTGTIYLDNIIDGIIKRIEGFNPSDLQVETFRTSIVFKSVRAALEGEFPDLEIKITDLIPWAFRDYGPRLPRSFAHSKLAVVGMACRMPGGGNDTELFWEILEQGRDVHTTVPADRFDLSTHYDPSGKTDNAATTPYGNFVDKPGLFDAGFFNMSPKEAEQTDPMQRLALVTAYEALEMAGVVPGRTASSNPKRIGTYYGQASDDWRELNASQNIGTYAVTGGVRAFGNGRINYYFKFPGPSFNVDTACSSGLAAVQVACSALWAGEADTVLAGGLNIITDPDNYAGLGCGHFLSKTGQCKVWDETADGYCRADGIGSVVIKRLEDAEADNDNIIAVVLSAATNHSAEAISITHPHAGNQKDNYRQVIDMAAVNPLDVSYIELHGTGTQAGDAVESESVLDVFAPRSPPRRPDQLLQLGAVKSNIGHGEAAAGIASFLKVLLMYQKNMIPAHIGIHTVINPTIPKDLEQRRVRLTQTNTPWPRLPGKKRIAMVNSFGAHGGNTTVLLEDAPERNKDVARENRSTHTVVISAKSKKSLQANIANLALHLEENPDIDLGDLSYTTCARRIHYTLRVGFAVSSIAGLKEALRKAGEKEALAEVRPTPGDVPPVVFAFTGQGAFYQGIARELFESFSYFRDEVLQLDHIVQRLGFQSIVPVIDGSIGENPSATVSQLSIVVIEIALAHLWTLLLGMQPSAVIGHSLGEYAALVVAGVLSTADGIFLAGRRAQLIEKCCTAGSHAMLSVRASVSEISKLLGNAKYEISCQNTLNDTVIGGTKANLDAARQVLESSSIKCVPVDVPFAFHTEQVDPVLDQLTRVAETVHFKAPSIPIISPLLRSVVFDGKTINSSYLIRATREPVHFAGAIEAAQDLGMVNDKTVWVDVGPHPICASFVRSLIPKARVASSCRRNEDNYATMAKNLVALHLAGCTPVWDEYFRANEKAYNLLTLPKYAWNDVNYWIQYIGTWTLDKAHLKYTGTNGPPQVKPSSSALRTSLIHEIIEETIGEETATLKTVSDLQHPEFLEAVHGHRMNNCGVATSSIWTDMSLTVGEYLYNKLAPGSKVHMNVGELEVLHATVANPAKNCTQNLYLDAHLDLRTQKMSLAWFNVDPATGSKAAESYATGSVRFEADAEKWKSEWERLTHLVLGRIETLESMAKDGQASQLSKALSYALFKNVVDYADHYRGMERVVMHDYEAFCDIKLTPERRGMFHTPPHWIDSVSHLAGLIMNGSDASNTRDYFFVTPGYESFRLLAKLDPDVKYQSYVRMFPLPEANMYGGDLYILQDNQIIGMVGHFKFRRVPRLLMDRFFSAEAASKQSVAASASSAPKTATKHAPLPASKPAQAPAEPTPSSLPTVQAQNTSPPQQVTPSKPAMNGVKTPEEEKPGKADAEGPNGTTSQPEATGVVGQCLQLIANETGQSVNELTPDATFVQLGVDSLMSLVLSEKFRAELGLEVKSSLFLECPTVGDMMDWLEQYC
What is the function of this protein?
Non-reducing polyketide synthase (NRPKS); part of the gene cluster that mediates the biosynthesis of asperthecin, an anthraquinone pigment (PubMed:18978088, PubMed:21866960).  Catalyzes the formation of the aromatic polyketide from acetyl coenzyme A and seven malonyl coenzyme A molecules (PubMed:18978088, PubMed:21866960).  Through its product template (PT) domain, catalyzes the cyclization of the polyketide backbone via C6-C11 aldolcondensation (PubMed:20479000).  Polyketide is subsequently hydrolyzed from the NRPKS by the action of the hydrolase aptB into endocrocin-9-anthrone (PubMed:18978088).  Endocrocin-9-anthrone is then oxidized into endocrocin by aptC (PubMed:18978088).  Endocrocin is likely to decarboxylate spontaneously to form emodin which explains why there is no decarboxylase in the asperthecin biosynthesis cluster (PubMed:18978088).  Finally, aptC or another endogenous oxygenase catalyzes additional oxidation steps to form asperthecin (PubMed:18978088).
What are the official names of this protein?
Non-reducing polyketide synthase aptA, NRPKS, Asperthecin synthesis protein A.
Protein: MAO1_SHEDO
Sequence: MDDTKRPLYLPFAGPAILEAPLINKGSAFSEEERIFFNLEGLLPYVIETIEEQAARAYAQFSNFSNDLDKHIYLRNIQDTNETLFYRLVRNNITEMMPIIYTPTVGLACERFSKNYRRNRGLFISYSNKDRIDDILNNSTRHKVKVIVVTDGERILGLGDQGIGGMGIPIGKLSLYTSCGGISPAYTLPITLDVGTDNQELLDDPMYMGWRHRRIEGQDYADFVEAFMEAVHRRWPDVLIQFEDFAQRNAMPLLERYKDQYCCFNDDIQGTAAVTVGSLLAASKAANTQLSKQRVVFLGAGSAGCGIAEAIVAQMISEGISEAQARSQVFMVDRLGLLQDNTANLLPFQQKLAQSSATVSQWHIEGDSVSLLNVINNAKPTVLIGVSGSPGQFTEAVIRAMHLHCPRPIVFPLSNPTSRVEATPEDVLNWTNGQALVATGSPFEPVTIGDETFEIAQCNNSFIFPGIGLGVLACRAKRVSDEMLMASSRALAECSPLGTTRTGSLLPKLDDIQKVSKYIAFAVAKVAMAQGLALPLTDELLNKSIEKNFWEPKYRRYKRTSF
What are the official names of this protein?
NAD-dependent malic enzyme, NAD-ME.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
Protein: TRUD_ECOLU
Sequence: MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHILVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDLSAFQLEGCQVLEYVRHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLIDICVKGVPNYFGAQRFGIGGSNLQGALRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQVVDGDALQLAGRGSWFVATTEELAELQRRVNDKELMITAALPGSGEWGTQREALAFEQAAVAAETELQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVVRELINTTGDYAHIAE
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: RL16_CLOP1
Sequence: MLMPKRVKHRKVQRGRMKGKATRGNFLAYGDFGIQATTCGWITSNQIEAARIAINRYIRRGGKLWIKIFPDKPVTEKPAETRMGSGKGSVEYWVAVVKPGRVLFELSGVDEEKAREAMRLASHKLPVKTKFVTRRDFEEMGGEE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: BACH1_HUMAN
Sequence: MSLSENSVFAYESSVHSTNVLLSLNDQRKKDVLCDVTIFVEGQRFRAHRSVLAACSSYFHSRIVGQADGELNITLPEEVTVKGFEPLIQFAYTAKLILSKENVDEVCKCVEFLSVHNIEESCFQFLKFKFLDSTADQQECPRKKCFSSHCQKTDLKLSLLDQRDLETDEVEEFLENKNVQTPQCKLRRYQGNAKASPPLQDSASQTYESMCLEKDAALALPSLCPKYRKFQKAFGTDRVRTGESSVKDIHASVQPNERSENECLGGVPECRDLQVMLKCDESKLAMEPEETKKDPASQCPTEKSEVTPFPHNSSIDPHGLYSLSLLHTYDQYGDLNFAGMQNTTVLTEKPLSGTDVQEKTFGESQDLPLKSDLGTREDSSVASSDRSSVEREVAEHLAKGFWSDICSTDTPCQMQLSPAVAKDGSEQISQKRSECPWLGIRISESPEPGQRTFTTLSSVNCPFISTLSTEGCSSNLEIGNDDYVSEPQQEPCPYACVISLGDDSETDTEGDSESCSAREQECEVKLPFNAQRIISLSRNDFQSLLKMHKLTPEQLDCIHDIRRRSKNRIAAQRCRKRKLDCIQNLESEIEKLQSEKESLLKERDHILSTLGETKQNLTGLCQKVCKEAALSQEQIQILAKYSAADCPLSFLISEKDKSTPDGELALPSIFSLSDRPPAVLPPCARGNSEPGYARGQESQQMSTATSEQAGPAEQCRQSGGISDFCQQMTDKCTTDE
What is the function of this protein?
Transcriptional regulator that acts as repressor or activator, depending on the context.  Binds to NF-E2 DNA binding sites.  Plays important roles in coordinating transcription activation and repression by MAFK (By similarity).  Together with MAF, represses the transcription of genes under the control of the NFE2L2 oxidative stress pathway (PubMed:24035498).
What are the official names of this protein?
Transcription regulator protein BACH1, BTB and CNC homolog 1, HA2303.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. CNC subfamily.
Protein: RS17E_PICTO
Sequence: MGSIRPSNIKRIAEEIVDNNPGIFNEDFENNKKILSEMLKNSVTKKTMNAIAGYVTRYILKKKSKEKSEMEQLGLA
What are the official names of this protein?
30S ribosomal protein S17e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS17 family.
Protein: PYRH_STAEQ
Sequence: MAQTSKYKRVVLKLSGEALAGDKGFGINPIIIKSVAQQVAEVAKMDCEIAVIVGGGNIWRGKTGSDLGMDRGTADYMGMLATVMNALALQDSLEQLDCDTRVLTSIEMKQVAEPYIRRRAIRHLEKKRVVIFAAGIGNPYFSTDTTAALRAAEVEADVILMGKNNVDGVYSADPKVDANAIKYEHLTHIQMLQEGLQVMDSTASSFCMDNNIPLNVFSIMEEGNIKRAVMGEKIGTLITK
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPD_AGRVS
Sequence: MNGLKPFIAKVASGQALTRDEAADAFNILMSGEATPAQIGGFLIALRMRGETVPEIVGAVTVMRQKMLPVIAPTDSIDIVGTGGDGTGTYNISTLAALIVAGAGVPVAKHGNKALSSKSGAADSLTALGVKLDIDPSVIGRCISEAGVGFMFAQLHHSAMRHVGPARVELGTRTIFNLLGPLANPAGVKKQLLGVYAPEWVIPLAETLRDLGSESIWVVHGNGLDEITTTGTTQVAALEQGKIRSFELTPGDFGVAQVELAALKGGDGEYNAKALRAVLEGEKNAYRDVALCNAAAALVIAGKANTLADGMALGAQSLDSGAALKRLETLITVSNGGHSA
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: OMT4_DICDI
Sequence: MEREENIEIKNSFDYILNSVTGLIESRLLYILVKHKVPEVFEDGLPKTYQQVAEKTQTSPIGIYKLLRYFTTSIGLFEEDLNNLGTFKKTPKSSLFTSDKYATFVEWCNNDLAYNMMKSLDLSIETGEPQCHKSLGVNSWWDLIKKPGEEEFFKNAMKVSSSEAIESALKFIDFSPFKKIVDIGGSHGRFVCEILEKYPNSHGINFDLESFFNGAGELIKNPRLEHKSGNFFESVPEGDCYILKRILHDWKDEDCIKILETIGKSILPGGKVIIFDCIINPKNYNKGHLYLDVMMFHFFGSEEKTIKQFSNISDKAGFKIDKVVNEIPNYCLIISKKD
What are the official names of this protein?
O-methyltransferase 4.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. COMT subfamily.
Protein: PB1F2_I75A0
Sequence: MEQEQDTPWTQLTEHINIQKKGNGQQTQRLGRPNLTQLMDHYLRIMSQADMHKQTVSWKQWLSLKNPTQGFLKTRALKRWKSFNKQGWTD
What is the function of this protein?
Plays an important role in promoting lung pathology in both primary viral infection and secondary bacterial infection.  Promotes alteration of mitochondrial morphology, dissipation of mitochondrial membrane potential, and cell death.  Alternatively, inhibits the production of interferon in the infected cell at the level of host mitochondrial antiviral signaling MAVS.  Its level of expression differs greatly depending on which cell type is infected, in a manner that is independent of the levels of expression of other viral proteins.  Monocytic cells are more affected than epithelial cells.  Seems to disable virus-infected monocytes or other host innate immune cells.  During early stage of infection, predisposes the mitochondria to permeability transition through interaction with host SLC25A6/ANT3 and VDAC1.  These proteins participate in the formation of the permeability transition pore complex (PTPC) responsible of the release of mitochondrial products that triggers apoptosis.
What are the official names of this protein?
Protein PB1-F2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB1-F2 family.
What are the subcellular locations of this protein?
Host mitochondrion inner membrane. Host nucleus. Host cytoplasm, host cytosol. Note=Inner mitochondrial membrane in most cells types. Otherwise is detected in the nucleus and cytosol.
Protein: STU1_PHANO
Sequence: MPDMLEQTNALLAALKKPSTNVDQRLQLFSNVKSNIKHNRVPEECQAPIFECIRIAISATTSATLVSTGFSTLSHFIKRLQLQRETAVITSQSSKLCALLLEKLGDARESHRSASLQILADLHPLCPLEVETLIHNAMKGTNARAKDTSMTWVVKMNQTENLPFRAYSAQMIANLEDADAGVRDTAKHAVVDLFTSAPEHAKANLKKQLVSTNVRKAIATYITAHLDGAATGGAHEEMPPPPPAVRERPLPTQRAQTLQPDHGIADALAAEQPPPTEAVTMDPIHIYTQRELEDIFRDMAPPFEGRESEGNWLARDKNTTKLRRILMGNAPAEFPGAFVAGIKSLLEGILKVANTLRTTMSTNGCQLVQELAKTLRHAIDPWVEILLQCFIKMCAATKNIAAQNGNVTVEAIISNVSYNNRILQHVSFAATNALRASWVKTLIRKHKAHVEHSGGLDTLEKIIRKGVTDANPKVREAYRSTYWTFALVWPQRAEAMFETLEKREKTALEKDPNNPNASLASSQSSAVSSFSKSVGAGAARNALKEKIAEQRRAKMAASKVPERPMSAAATYSPVKSASTKSLSARTASTASTASNGPARPPSAMSGESTKSALKNSSGTGSLMSGTVRRPIRRPELNRPATADPYAVRRAGNGKTTPSMTPEKTPAVTTTKKSVAPKSSVRPRAQTQNSPNVSPIRSRSRLGQSTTVQKTASASSRQASPAPSASKDEDLELTIVKPFVRSQSHHDPGTIPFRQRNGLDKSAVFDNETVLSGDEDNFTMVIPNLARPTAQSIHHTPPKTHSPSHLSAPSPRASMLRSPKSMGDINGFGFRSSTRSPRVRSPDRPSTRGTDAQEGVQVFEDPFVGDEPAAVEHEVEKPVLGELPINEKNIERRPSNESISSDTVMGNASEDRPRGHHKTTSTGSVLYSESNDTNNAEVLKNRQLLASGIKKIESRTVESHMFRRMQDMIRSNHEIWGANDENFGCLLLACLDFLEVPTEELKTTPIKVANLKVQALATIRAMLSLYRKETAKYFSRVLCTVLQTKAQYENTSHIAIDLETTAEEIVRYGQTSDCLNAVLALIEDLPSSTPTSSPSSKSSLTSLPGAGQTRTATMALSTLAALIQISGAKNITLSPDQTSRLGKLAVRCMDDQDADVRKSNIEFCIALHERIAAPAGEQENDGFWRAVAGAREQHLNLLTYYLAKRRAA
What is the function of this protein?
Microtubule binding protein that promotes the stabilization of dynamic microtubules.  Required for mitotic spindle formation (By similarity).
What are the official names of this protein?
Protein STU1.
What is the protein family that this protein belongs to?
Belongs to the CLASP family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Nucleus. Cytoplasm, cytoskeleton, spindle.
Protein: 6PGL_CITK8
Sequence: MKQTVYTASPESQQIHVWSLNHDGSLKLVQVVDVPGQVQPMVVSPDKRYLYVGVRPEFRVLAYRIAPDDGALTFAAESALPGSPTHISTDHQGRFVFVGSYNAGNVSVTRLDDGLPAGVVDVVEGLEGCHSANISPDNRTLWVPALKQDRICLFTLSDDGKLVAQEPAEVTTVEGAGPRHMAFHPNQQYAYCVNELNSSVDVWELKDPHGNIECVQTLDMMPADFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLTKEGFQPTETQPRGFNVDHSGKYLIAAGQKSHHIAVYAIAGEQGLLTEKGRYAVGQGPMWVVVNAY
What is the function of this protein?
Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
What are the official names of this protein?
6-phosphogluconolactonase, 6-P-gluconolactonase.
What is the protein family that this protein belongs to?
Belongs to the cycloisomerase 2 family.
Protein: LMIP_MOUSE
Sequence: MYSFMGGGLFCAWVGTILLVVATATDHWMQYRLSGSFAHQGLWRYCLGNKCFLQTESIAYWNATRAFMILSALCATSGIIMGVLAFAQQSTFTRLSRPFSAGIMFFASTLFVLLALAIYTGVTVSFLGRRFGDWRFSWSYILGWVALLMTFFAGIFYMCAYRMHECRRLATPR
What is the function of this protein?
Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization.  Acts as a receptor for calmodulin.  May play an important role in both lens development and cataractogenesis.
What are the official names of this protein?
Lens fiber membrane intrinsic protein, MP17, MP18, MP19, MP20.
What is the protein family that this protein belongs to?
Belongs to the PMP-22/EMP/MP20 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NCAP_I61A1
Sequence: MASQGTKRSYEQMETGGERQDATEIRASVGRMIGGIGRFYIQMCTELKLSDYEGRLIQNSITIERMVLSAFDERRNKYLEEHPSAGKDPKKTGGPIYRRIDGKWMRELILYDKEEIRRVWRQANNGEDATAGLTHIMIWHSNLNDATYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTIVMELIRMIKRGINDRNFWRGENGRRTRIAYERMCNILKGKFQTAAQRAMMDQVRESRNPGNAEIEDLIFLARSALILRGSVAHKSCLPACVYGLAVASGHDFEREGYSLVGIEPFKLLQNSQVFSLIRPNENPAHKSQLVWMACHSAAFEDLRVSGFIRGKRVVPRGKLSTRGVQIASNENVEAMDSSTLELRSRYWAIRTRSGGNTNQQKASAGQISVQPTFSVQRNLPFERATVMAAFVGNNEGRTSDMRTEIIRMMESAKPEDLSFQGRGVFELSDEKATNPIVPSFDMNNEGSYFFGDNAEEYDN
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: Y1501_LISMO
Sequence: MAEEHNHNHEEENIIWITNEEGKEEAYEILFDFDSEDFDKSYVLYFPAGKGEDEEIEILASSYIQDEEGKQGQLKPVETDEEWDMIEEILATFLADEDEE
What are the official names of this protein?
UPF0473 protein lmo1501.
What is the protein family that this protein belongs to?
Belongs to the UPF0473 family.
Protein: RECR_SYNR3
Sequence: MWRDDLPRFQPSHCRPLTVFTRPLARLIEQFERLPGIGPRTAQRLALHLLRQPEEQSRAFADALLAARQQVGQCQRCGHLSADPICDICRNPERNIGVICVVADSRDLLALERTREFSGSYHVLGGLISPMDGIGPEALGIQPLLQRLDPEQVEEVILALTPSVEGDTTSLYLARLLKPFCRVTRIAYGLPVGSELEYADDVTLARALEGRRIVE
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: DTD_BACCZ
Sequence: MRVVLQRSKEASVTVDGEIVGQIPFGLTLLVGITHEDTEKDATYIAEKIANLRIFEDESGKMNHSVLDVEGQVLSISQFTLYGDCRKGRRPNFMDAAKPDYAERLYDFFNEEVRKQGLHVETGKFGAMMDVSLINDGPVTLIVESK
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASZ1_AOTNA
Sequence: MAARALRGPAVAGGGESSDSEDDGWEIGYLDWTSQKLKGQTLPIEEKKEKFKKALTTGDVSLVQELLDSGIISVDDTFRYGWTPLMYAASVANAELVRVLLDRGANASFEKDKQTILITACSAHGSEEQILKCVELLLSRNADPNVACRRLMTPIMYAARDGHTQVVALLVASGAEVNTQDENGYTALTWAARQGHKSIVLKLLELGANKMLQTKDGKLPSEIAKRNKHYEIFNLLSFTLNPLEGKLQQLTKEETICKILTTDSDRENDHIFSSCAAFGDLEVFLHGLGLEHMTDLLKERDITLRHLLTMREDEFTKYGFTSKDQQKILAALKELEVEEIQFGDLSEEARLEISGDEFLNFLLKLNKQCGHLITAVQNIITELPVNSQKIVLEWASPQNFTSVCEELVNNVEDLSEEVCNLKDLIQKLQNERENDPTHIPLREEVSTWNSRILKRTAITVCGFGFLLFICKITFQRK
What is the function of this protein?
Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity.  Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons.  Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process.  Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons.  May act by mediating protein-protein interactions during germ cell maturation (By similarity).
What are the official names of this protein?
Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1, Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein.
What are the subcellular locations of this protein?
Cytoplasm. Note=Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. Specifically localizes to pi-bodies, a subset of the nuage which contains primary piRNAs (By similarity).
Protein: Y552_TREPA
Sequence: MQSLEPLITKQLRPAPVGVPEGTPQQVLYVLTWSALTQVDKYRISTAVPAVSGVYELYYMDEARALNLLTAAHAWYGGLRGNVRAAVDPHETADPARRALLTDATLYYRYSVSHSRDDMCDLVWFLHTQYFPGSVRVQHSGRYSAIFVQERAPDRVYWLEDLPHRTERGSMQTRVSK
What are the official names of this protein?
Uncharacterized protein TP_0552.
Protein: CHL18_DERPT
Sequence: MTRLSFTVLIFLAAYFGSNIRPNVATLDPKTVCYYESWVHWRQGDGKMDPEDIDTSLCSHIVYSYFGIDASSHEIKLLDQYLMITLHDMEHFTKHKGNAKAMIAVGGASMSDQFSKTAAVEHYRETFVVSTIDLMTKYGFDGVMIDWSGMQAKDSDNFVKLLDKFDEKFAQTSFVMGVTLPATIASYDNYNIPAISNYVDFMNVLTLDYDGPWAYTVGHASALPEQLKTLEAYNKRGAPRHKMVMAVPFFARTWILEKMDKQDVGDKASGPGPKGQFTQTPGFLSYNELCVQIQAETNAFSITRDHDNTAIYAVYVHDNHAEWISFEDRHTLGDKARNITEQGYGGMSVYTLSNEDVHGVCGDKNPLLHAINSNYFRGIVTEPTVVTVTPVTHTTEHVTDIPGVFHCHQEGFFRDKTYCAKYYECKKGDFGLEQTVHHCPNHSQAFDEVSRTCVDHAKIPGC
What is the function of this protein?
Probably a non-catalytic chitinase-like protein, which binds to insoluble chitin and enhances the activity of the catalytic chitinases (PubMed:16776685).  Has weak chitin-binding activity (PubMed:27548813).
What are the official names of this protein?
Chitinase-like mite allergen Der p 18.0101, Allergen Der p 18, Chitinase-like house dust mite allergen Der p 18, Group 18 allergen protein.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LAN1C_RUMFL
Sequence: MNKNPIYRSEEEAKNIACGNVAAELDENSQALDAINGAGWKQTIACTIAQGTLGCLVSYGLGNGGYCCTYTVECSKTCNK
What is the function of this protein?
Lanthionine-containing peptide antibiotic (lantibiotic) only active on Gram-positive bacteria in synergy with Flvbeta peptides, which are encoded by the same operon than Flvalpha. a.  Shows antibacterial activity in synergy with Flvbeta. b, Flvbeta. c, Flvbeta. e and Flvbeta. g.  Does not show antibacterial activity when tested with Flvbeta. a, Flvbeta. d, Flvbeta. f and Flvbeta. h (By similarity).  The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores (By similarity).
What are the official names of this protein?
Lantibiotic Flvalpha.c.
What are the subcellular locations of this protein?
Secreted.
Protein: SECA_SERP5
Sequence: MLVKLLTKVFGSRNDRTLRRMRKAVELINQMEPDMEKLSDDELKAKTNEFRARLEKGEVLENLLPEAFAVVRESSKRVFGMRHFDVQLLGGMVLNDRCIAEMRTGEGKTLTATLPAYLNALSGRGVHVVTVNDYLAQRDAENNRPLFEFLGLSIGINLPGMPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYIRVNKLIPQLIRQEKEDSDSFQGEGHFSVDEKARQVHLTERGLILIEEMLMEAGIMDEGESLYSPTNIMLMHHVTAALRAHVLFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEGVEIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTIVVPTNRPMIRKDMPDLVYMTELEKIGAIIEDIRERTVNGQPVLVGTISIEKSEVVSRELTKAGIEHKVLNAKFHAMEADIVAQAGQSSAVTIATNMAGRGTDIVLGGSWQAEIEQLEDPTEEQIAEIKAAWKIRHDAVLAAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDRVSSMMRKLGMKEGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYSQRNELLDVSDVSETITSIREDVFKTTIDGYIQPESLEEEWDIEGLTERLKNDFDLDMPIAEWLDKEPQLHEETLRERILEKAKEEYQRKEEVVGVEMMRNFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKDPKQEYKRESFNMFATMLESLKHEVISVLSKVQVRMPEEVEALELQRREEAERLAKQQQLSHYEENALVTEDPNAPATAERKVGRNDPCPCGSGKKYKQCHGRLQS
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: TRPD_ACTP7
Sequence: MQLDNILSQLFENQALTKAESQYFFEQVIQGNVSNEQLAGALIALKVRGETIEEIAGAVEAAFANATAFPAPDYAFADIVGTGGDGQNTINISTASAIVAATLGYKVAKHGSRSVSSKTGASDVLSALGINVAISPQTARQALDENNLCFLFAPLYHAGFKHAVPVRQVLKTRTLFNILGPLVNPAHAKRQLLGVYSPEVLKIYAETVRSLNHQHSIVVHGAGLDEVTVHGETLVAEIEHGEIHYFSLTPEDFGIQRHSIEALKGGEPAENAEKITALLQGKGEAAHIDAVAVNTAMLMRTFGERDLKANVQRVKDLLSTDKAYQTLQNLAQYQ
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.