PharMolix/UniProtQA huggingface dataset:
Protein: ICP4_PSHV1
Sequence: MFWHQPRQQQLRQLQRAASGAGKHQRRSPPQTLGDDGDAAAQVPPSPTGALLAFLNQHASEEGGAAAASADGRVSVSPGFCSSILPEHSQDLFAFSDPTSASPQPVPMDASLSLFTPPVPDCGRDVGEEAEGAVAPSWRAPLPAPQWRPVHGPSWWLSSSSPSGSSRGSVTSPQYSGEETSDAASGAPTPPPQSSGSSYVYGQALADLMAMIQEIPAPPRSVPDCRRGEPVSEDGMADRCETDASCYTTDEPMEAEPSEPAGGVSWLGERADRMRADQSPRGLGAEPHVAEAGRPSSCVGEERADVVAIAAVEERKEAARRSPDAERNDDEEEYESLPCAQEFFTSQELAEINARAIAESDEAEDEDAGSPAARSQSSPFPSLGPAVFVLAPTSAKSSRGMRKKAIAVSRVVPDNDGEPDPCADGPGRDHVSSAQSAGANGALETETSVPRSATAPAGAVAACAQNTKRGYWRGAAAGHAEEETDSDDEDVLVVDVSACAEPFESFAQRQQPRQQQHAPRNKPARQRLRAGAIVAAASGNTLTVPSEPPHPSLAPLWKMLNLWLSEEWPAQGGGQDEGEAAVSASLLAPGSLPELPDMCPRVAVGIISHALAVDLSAPGGRITVDEALLPKPPAADYVYYGKTGYRPSMAAHPDVRRAAEEFSASDAAARVYVEEFGMAVEQHERLVAEFMLQPLSRVSHSYGGSRLNKTEKNLCKICLPPDGGDDRDGGGKSRGGRGGGSKDASRTAMATGVPHIVHAMRDGRAALALPHLMDVIRVCRRYDASQKTYLLSCLRLAFAPLVFPGASPPVGADDSPWPTSPIRECAAALREGFRALNDIRAEQDPPADERSRELALPLDRAITAARRVAATAAGLLNAVGASVVHDGRVGLPAFFLRGVTERREDLFSAARRCPRALYSWERSMRATTAALWGHLASRGPIAAPVADLEELSQALSAVLSVTSVPDGGDVRYAFAEADEGWRALAVMLGGGAVRTSSGESGDAETDAAYALLAPGKQSSAGVNHPRGRPGRATASSPRTPASRPPHGSAAAPPSGRDSPPGALNVPEAAEEELRLAAARDTTGDLLSDEAGTDDDGDAPVVISYVGPSSPPGVEDPSPDGLAALRPLPEGYVPRPGDVLRGDPGADENDDDARAPCRVGDASPPRQLPSSSSFASSSLASAVPGDPYLPRSVAEPTLCRLAEHLQSDDGWTRAFANDPVGLAEFARRSTPGRRLGGQRRLDQLLSWTRRHSPRRRYSLIVLVSEKRPGDFRERAYAAAALAGRACVPGSACDPETWRDAEDHPSPSADAQSPLRSRPSRDCFPPRIAQPEASDDDDVGEGGTALLSAGDIGFAGAVESMLRRALSRQGQACAVVDARDDKDVLSAAAPRFPRGKPGLIYLRVAPPSEACVANLPSLGPSASPHRGVGGKHRDKRPCLAEGTPSAPSCRDAARATAPLSGDPVAHRLLMHRPAKPLVGEEACAALLGGKAGRRGQDVPLPFLTAATLRKVARVARELDPGWGHGDLGCESAVVFPPAAPPGPELADRHADRRRSTKGPQRPGGKRPRSSSSSSSASHDRSPSSSSRRRDGRPSSRRRPSRRMSARPPSRPPAAVILRASWRYAEEVAREMLDAAASRFDEADGEDPLPPAACGGKPIAPETLVALCEQRGRGPTSLPRAPTPRSGEALAAPRRSGAKDPRQGQYCPSARRSEAPHSPSPRDVALRLLERQQELNRQLLLELRRGSCEISPSPRRRDAEGRRFGCRQDDDDGYDYEGGRESPERVLGRRQSRRDSVPVRRRSGAANCGGRWMISAGRSSSSSSSSSSSSSSSPSSRPSRSATPSLSPSPSPPRRAPVDRSRSGRRRERDRPSANPFRWAPRQRSRADHSPDGTAPGDAPLNLEDGPGRGRPIWTPSSATTLPSRSGPEDSVDETETEDSAPPARLAPSPLETSRAEDSEDSEYPEYSNPRLGKSPPALKSREARRPSSKQPRRPSSGKNGHTDVSAASAFFLGRPAPGSCGRRPLGARVRGGTER
What is the function of this protein?
This IE protein is a multifunctional protein capable of migrating to the nucleus, binding to DNA, trans-activating other viral genes, and autoregulating its own synthesis.  It is required for the switch from immediate-early to early mode of gene expression (By similarity).
What are the official names of this protein?
Major viral transcription factor ICP4 homolog.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae ICP4 family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: TGL2_YEAST
Sequence: MKNDNKANDIIIDSVKVPDSYKPPKNPIVFCHGLSGFDKLILIPSVFHLTNLISNSIVHNMAENFMQDDEDKSDNKYTNLLEIEYWIGVKKFLQSKGCTVITTKVPGFGSIEERAMALDAQLQKEVKKIESKDKRHSLNLIAHSMGGLDCRYLICNIKNRNYDILSLTTISTPHRGSEMADYVVDLFENLNALRVSQKILPICFYQLTTAYMKYFNLVTPNSPKVSYFSYGCSFVPKWYNVFCTPWKIVYERSKGCPNDGLVTINSSKWGEYRGTLKDMDHLDVINWKNKLQDDWSKFFRTTTVGEKVDILNFYLKITDDLARKGF
What is the function of this protein?
Mitochondrial triacylglycerol (TAG) lipase with activity toward long-chain diacylglycerols (DAGs) and triacylglycerols (TAGs) (PubMed:9544243, PubMed:19959834).  Involved in mitochondrial lipid metabolism (PubMed:31483742).
What are the official names of this protein?
Triacylglycerol lipase 2, Lipase 2, Neutral lipid hydrolase.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion intermembrane space. Note=Imported into the IMS via the MIA40 disulfide relay system.
Protein: NADD_BUCA5
Sequence: MKKLCAIFGGNFDPIHYGHINLAEKLAKDISIKKIILLPNNYPPHRNKTQTSISDKIKMIKLAIHNNPLFEISYLETKKNNIFYTIDTLKKIRKKISHLEPLCFIIGEDNLQTFYLWKNWREILLYSHLLIYPRKHKKQKNDELEKWIHSNTVYDCNLLHKQPCGLIFFSHAPCINISSSRIRKNYFYGKNSHSLLPSIVNNYILLKKLYYTNQ
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: CUE4_SCHPO
Sequence: MQPEQLAGCAVVLTVTVLTLRWMFRVDKGGEVSESRTSSSGVDNEPPVNSEHVHLVKTVFPHLESSAIAYDLQKTKNVDATIENALRGQPLPLPPRNSSLYARFPLSAGAGASSHSEETTPSHEVTSNVSSGSSASSLASNEHRSLIETYNLSSRISSSDNSSSSTGNEEVRNRSKLPSSKKEREELFRKRKEEMILAARKRMEGKIKGEKQDKN
What are the official names of this protein?
CUE domain-containing protein 4, mitochondrial.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RNY_CALS4
Sequence: MNHLLRRCRSISYVGLIITALIAILIGFLAGFLARKVIAESKIKSAENLARTILESAKKDAENKKREALLEAKEEIHRLRSDFEKEVRDRRGELQRLEKRLLQKEEILEKRAESLEQKEILLEQKQKEIQQLEEQITLLHKKQLEELERISGLTQEEAKSILLESVQKEIQHDMAVMIKEMENKAKEEADRRAREIVGLAIQRCAADHAAETTVSVVTLPNDEMKGRIIGREGRNIRTIETLTGIDLIIDDTPEAVVISGFDPIRREIARIALEKLIEDGRIHPARIEEMVEKAKKEVDNMIIKAGEEAAFEVGVHGLHPELIKLLGRLKFRTSYGQNVLKHSIEVAHLAGLMAYELGADASIAKRAGLLHDIGKAVDHEVEGPHVMIGAELAKRYHESDAVVHAIMAHHNDVEPQTIEAVLVQAADAISAARPGARREALEAYIKRLDKLEQIANSFEGVEKAYAIQAGREIRIMVKPEAISDDELVILARNISKKIEEEVEYPGQIKVTVIRETVAIDYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: EUTC_SALNS
Sequence: MDQKQIEEIVRSVMASMGQDVPQPVAPSTQEGAKPQCAAPTVTESCALDLGSAEAKAWIGVENPHRADVLTELRRSTAARVCTGRAGPRPRTQALLRFLADHSRSKDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLSPEAIDALKSQCVMNPDVQVVVSDGLSTDAITANYEEILPPLLAGLKQAGLNVGTPFFVRYGRVKIEDQIGEILGAKVVILLVGERPGLGQSESLSCYAVYSPRVATTVEADRTCISNIHQGGTPPVEAAAVIVDLAKRMLEQKASGINMTR
What is the function of this protein?
Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds.  Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
What are the official names of this protein?
Ethanolamine ammonia-lyase small subunit, EAL small subunit.
What is the protein family that this protein belongs to?
Belongs to the EutC family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: VP4_ROTBS
Sequence: MASSLYRQLISQNYYSTGNEILLDQQTNKTTVDYVDAGNYTYAQLPPTTWGAESTYESAFSAPEITGPYTNTVIKLSDLSDSNVWVLYQKPTSTVKLLKNGPESYSWNLAAFELWYGKANTTVTSDYYSGMTNSEKSVEVDHDSLVLFWNEGSTALSNKVINFSWNVGGVLIKLTSNTRIDICMANMDNFTSDSFNWEEWTHNFPRSASMNIYTDYYLASVDPYSQIRALQQPIITTVEMKMVKVKREGSINVDEVVSKDSLWQEVRYVRDITLQCKIESEVVKGGGWGYDYTSVAFKTINHTYSYTRAGEAVNAHVTISFNNLKERSYGGSLPTDFKIGRFDIIDVDTYMYIDYWDDSEIFKNMVYVRDLRADMGGFNYSSAMSYYFRIPVGQYPGLHSSGVRFTYERSLLSQQFTDQVALNSMRFVFRATSSDGWFMTAGNINARRIASGTGFAYSDGYVTETVGTVSFISLIPSNPNYQTPIASSSTVRMDLERKINDLRNDFNELASSVALGDILSLAMSPLTFANLLESVPAIASSVKDVAANVMKKFKTTKMFKKAAKPKYKEYIIGDLLEDVTNLPRSTTAMDFDDITSAVMVSTTNRLQLTDVETLSEIVARSADDFIPNRAYRMIEDGMVHEATPNGVFSYDLATLQQRNFDMEKFMQLASKSPVISAIVDFATLKAMRDTYGVSTDIMYKLVASDAPTIVSFINNNNPLIRNRIEGLLRQCRI
What is the function of this protein?
Forms the head of the spikes and mediates the recognition of specific host cell surface glycans.  It is the viral hemagglutinin and an important target of neutralizing antibodies.
What are the official names of this protein?
Outer capsid protein VP4, Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP4 family.
What are the subcellular locations of this protein?
[Outer capsid protein VP4]: Virion. Host rough endoplasmic reticulum. Host cell membrane. Host endoplasmic reticulum-Golgi intermediate compartment. Note=The outer layer contains 180 copies of VP4, grouped as 60 dimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple- layered particles. SUBCELLULAR LOCATION: [Outer capsid protein VP8*]: Virion. Note=Outer capsid protein. SUBCELLULAR LOCATION: [Outer capsid protein VP5*]: Virion. Note=Outer capsid protein.
Protein: RPOZ_STAA8
Sequence: MLNPPLNQLTSQIKSKYLIATTAAKRAREIDEQPETELLSEYHSFKPVGRALEEIADGKIRPVISSDYYGKE
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: RL27_MICLC
Sequence: MAHKKAGSSSKNGRDSNPQYLGVKRYGGEDVNAGEIIVRQRGTKFHPGRNVGRGKDDTLFALSAGSVAFGQRRGRKVVDIVPAAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: RIMM_CLOD6
Sequence: MKEKLTHFKVGQIVNTQGLKGEVRVYPLTDDIERFDELKDFYLGKDLNNKLAVEKVRYKGSMVIMKIKGIDSIEKAEKLKNKFMYVSREDSRELEEGEFFIADMIGMEVLTVDGKYVGILEDVLQYSANDVYVVKGEEDKEFMIPAIKKFVPTIDIDERKMIIDPIKGMID
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLX1_MOUSE
Sequence: MDHAARPGRFFGVYLLYCQNPRHRGRVYVGFTVNPARRVRQHNAGRKKGGAWRTSGRGPWDMVLIIHGFPSAVAALRFEWAWQHPQASRRLTHVGPRLRSEAAFAFHLRVLAHMLRVPPWVRLPLTLRWLRPDFRHELCPAPPAHMPIAFGPPPPQPLVPKRPAVSEADSERQLDLGTKARCSLCARLLQDEEGPLCCPHPGCPLRAHIICLAEEFLQEEPGQLLPLEGHCPSCKKSLLWGNLVGQCHADTEEEEDLELEEEHWTDLLET
What is the function of this protein?
Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination.  Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.  Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs).  Resolves HJs by generating two pairs of ligatable, nicked duplex products.
What are the official names of this protein?
Structure-specific endonuclease subunit SLX1, GIY-YIG domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the SLX1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARY2_RAT
Sequence: MDIEAYFERIGYQSSRNKLDLEELTEILQHQIRAIPFENLNIHCGESMELNLEVIFDQVVRKKRGGWCLQVNHLLYWALTKMGFEATMLGGYVFNTPANKYSSGMIHLLVQVTLSGKDYIVDAGFGRSYQMWEPLELTSGKDQPQVPAIFRLTEENGTWYLDQIRREQYVPNQEFVNSDLLEKNKYRKIYSFTLEPRTIEDFESINTYLQTSPASLFTSKSFCSLQTLEGVHCLVGSTLTYRRFSYKDNIDLVEFKSLTEEEIEDVLKTIFGVSLERKLVPKHGDRFFTI
What is the function of this protein?
Participates in the detoxification of a plethora of hydrazine and arylamine drugs.  Acetylates only arylamines.
What are the official names of this protein?
Arylamine N-acetyltransferase 2, Arylamide acetylase 2, N-acetyltransferase type 2, AT-2, NAT-2.
What is the protein family that this protein belongs to?
Belongs to the arylamine N-acetyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IXR1_YEAST
Sequence: MNTGISPKQDDASNSNLLNIGQDHSLQYQGLEHNDSQYRDASHQTPHQYLNQFQAQPQQQQQQQQQQQQQQQQAPYQGHFQQSPQQQQQNVYYPLPPQSLTQPTSQSQQQQQQQQQQQYANSNSNSNNNVNVNALPQDFGYMQQTGSGQNYPTINQQQFSEFYNSFLSHLTQKQTNPSVTGTGASSNNNSNNNNVSSGNNSTSSNPAQLAASQLNPATAAAAAANNAAGPASYLSQLPQVQRYYPNNMNALSSLLDPSSAGNAAGNANTATHPGLLPPNLQPQLTHHQQQMQQQLQLQQQQQLQQQQQLQQQHQLQQQQQLQQQHHHLQQQQQQQQHPVVKKLSSTQSRIERRKQLKKQGPKRPSSAYFLFSMSIRNELLQQFPEAKVPELSKLASARWKELTDDQKKPFYEEFRTNWEKYRVVRDAYEKTLPPKRPSGPFIQFTQEIRPTVVKENPDKGLIEITKIIGERWRELDPAKKAEYTETYKKRLKEWESCYPDENDPNGNPTGHSHKAMNMNLNMDTKIMENQDSIEHITANAIDSVTGSNSNSTNPNTPVSPPISLQQQPLQQQQQQQQQQQHMLLADPTTNGSIIKNE
What is the function of this protein?
Binds to platinated DNA and confers sensitivity to the anticancer drug cisplatin.  Activate the expression of the COX5B gene.
What are the official names of this protein?
Intrastrand cross-link recognition protein, Structure-specific recognition protein, SSRP.
Protein: RL13_ALKEH
Sequence: MKTYSAKPADVQRDWYVVDANGKTLGRLASEVAYRLRGKHKPEYTPHVDTGDYIVVVNAEKIAVTGNKASDKMYHQHTGYIGNMKSISFEKLIDKAPERVIEKAVKGMLPKNRLGRAMIKKLKVYAGGEHRHAAQQPQPLDI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: NQRC_PASMU
Sequence: MFKNKDSVGGTLLVIILLSLACSIIVAGSAVLLKPTQIEQKELDKQKNILSVAGLLQPTTKNSEIKTIYANNIEARLVDLNTGDFAPAQPGFDAAKAVKNPAESTALSAEDDVAGIRVRANFAEVYLVKNDAGQVTQVVLPFYGKGLWSMMYGFMSVQPDGNTVNGITYYDQGETPGLGGEIENPKWQAQFPGKKLYTADNQVGLYVGKGASANAEHGIDAISGSTLTSNGVNNSFKFWLGQKGFGPFLAKLKAGVLNNG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit C, Na(+)-NQR subunit C, Na(+)-translocating NQR subunit C, NQR complex subunit C, NQR-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the NqrC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: MSS11_CANAL
Sequence: MSKPPPQHQSKNANNSLSSPVSDKQSNDSRQLLLAHLYNYFKTNGLEETAQALLIECNNTIPKATTNSKGYSLDNSGPDQKDTFLDQWWGLLWSIQSSINPNLNQMTNPSGILTPQHQMIVQQRMLQQQQQQAQQQQQQAQQQQAQQQQQQQQLLQQQRLQQQAMIQQQHQQQLINNLSARQQQVGLSTTTNQMGPPGSNSNNLQSNMSPNNEQLQSQARLQQLKLQFQQQQQQQLQQQQQQLQLQQQQQQQQQQQQQQQQQQQQQQRQQQRQRQKKFQRQLSTSSQKSPVINNGQPQQQLQQDQRPASAPQNQPTPGNNNNNNNNTNAVSPKLHRQSVDDYQMNLLQMENQNNSQRQKYLNNQQTRNSQQQQQQQQSQSQSQQSSPFQPPAQQPKNSTTTSTNTTTSRAQKSSRKQQPKNSRRQSVQQQQQQQPQQQPQQSQQMSTSSQSFTAANNSNNVNNTFDISPQIQDQGMLSTKEQQQQPQQPQPQPQSQPQSQSQSLPSNNNNNNNNKQDVVNVVFDDAFFSGNLLLDDFNEFANSTSNNGNGNGNNDMNSQFNNTQTERIMFSMPPNQNQNQFPSQSGDGGGGGGGSMQPNFFEGIELGDGNNSGNGDDDDAPIITTDWLSSMGSGPGYE
What is the function of this protein?
Transcription factor that regulates pseudohyphal differentiation, invasive growth, floculation, adhesion and starch metabolism in response to nutrient availability.
What are the official names of this protein?
Transcription activator MSS11.
What is the protein family that this protein belongs to?
Belongs to the MSS11 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: FTSK_MYCTO
Sequence: MSSKTVARSGTRTSRSKATSRGASRSARSAVPRKRSRPVKGVGRPSRRHHRSLLVSTGLACGRAMRAVWMMAAKGTGGAARSIGRARDIEPGHRRDGIALVLLGLAVVVAASSWFDAARPLGAWVDALLRTFIGSAVVMLPLVAAAVAVVLMRTSPNPDSRPRLILGASLIGLSFLGLCHLWAGSPEAPESRLRAAGFIGFAIGGPLSDGLTAWIAAPLLFIGALFGLLLLAGITIREVPDAMRAMFGTRLLPREYADDFEDFADFDGDDADTVEVARQDFSDGYYDEVPLCSDDGPPAWPSAEVPQDDTATIPEASAGRGSGRRGRRKDTQVLDRIVEGPYTLPSLDLLISGDPPKKRSAANTHMAGAIGEVLTQFKVDAAVTGCTRGPTVTRYEVELGPGVKVEKITALQRNIAYAVATESVRMLAPIPGKSAVGIEVPNTDREMVRLADVLTARETRRDHHPLVIGLGKDIEGDFISANLAKMPHLLVAGSTGSGKSSFVNSMLVSLLTRATPEEVRMILIDPKMVELTPYEGIPHLITPIITQPKKAAAALAWLVDEMEQRYQDMQASRVRHIDDFNDKVRSGAITAPLGSQREYRPYPYVVAIVDELADLMMTAPRDVEDAIVRITQKARAAGIHLVLATQRPSVDVVTGLIKTNVPSRLAFATSSLTDSRVILDQAGAEKLIGMGDGLFLPMGASKPLRLQGAYVSDEEIHAVVTACKEQAEPEYTEGVTTAKPTAERTDVDPDIGDDMDVFLQAVELVVSSQFGSTSMLQRKLRVGFAKAGRLMDLMETRGIVGPSEGSKAREVLVKPDELAGTLAAIRGDGGE
What is the function of this protein?
Essential cell division protein that coordinates cell division and chromosome segregation.  The N-terminus is involved in assembly of the cell-division machinery.  The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region.  Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity).
What are the official names of this protein?
DNA translocase FtsK.
What is the protein family that this protein belongs to?
Belongs to the FtsK/SpoIIIE/SftA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Located at the septum.
Protein: ERG_MOUSE
Sequence: MIQTVPDPAAHIKEALSVVSEDQSLFECAYGTPHLAKTEMTASSSSDYGQTSKMSPRVPQQDWLSQAPARVTIKMECNPSQVNGSRNSPDECSVNKGGKMVGSPDTVGMSYGSYMEEKHVPPPNMTTNERRVIVPADPTLWSTDHVRQWLEWAVKEYGLLDVDVLLFQNIDGKELCKMTKDDFQRLTPSYNADILLSHLHYLRETPLPHLTSDDVDKALQNSPRLMHARNTGGAAFIFPNTSVYPEATQRITTRPDLPYEPPRRSAWTGHSHLTPQSKAAQPSPSAVPKTEDQRPQLDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSSNSNCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPHPPESSLYKYPSDLPYMGSYHAHPQKMNFVSPHPPALPVTSSSFFASPNPYWNSPTGGIYPNTRLPASHMPSHLGTYY
What is the function of this protein?
Transcriptional regulator.  May participate in transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent modification of local chromatin structure.
What are the official names of this protein?
Transcriptional regulator ERG.
What is the protein family that this protein belongs to?
Belongs to the ETS family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Protein: MTNB_DICDI
Sequence: MSNFDSEHPRVLIPELCKLFYGNGWVTGTGGGISIKRDKEIYIAASGVQKERILGEDIFVMDENENEISTPPTEKKLKASQCTPLFFNAYKYRDAGAVIHTHSQHAVMVTLLYQTEFIITHQEMIKGILSGHGENAKYLQYFDRLVIPIIENTPHERDLKERMHKAMEKYPNANAVLVRRHGVYVWGPDWVKAKTMCECFDYLFEIAIKMKQMGLDPTEVPHANEECCYDC
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
What are the official names of this protein?
Probable methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENGB_CLOK5
Sequence: MEIKQAEFIISAVHPSQYPKDKRIEIAFVGRSNVGKSSLINALTNRKKLVKVSGTPGKTRLINFFLINNEFYFVDLPGYGYAKISKTEKKSWGKVVEDYLRGREELKRVILLLDCRHKPTNDDITMYKWLKYYNYNTIIVATKVDKVSKSQLFKNLKIIKDTLKPETGDEILTFSSLNKQGKEEFLKVLESVIDFYS
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: LIGB_YERPA
Sequence: MNILNLKIIMFLLISNTIVVGGAWATSTCPDWPATRIAVEINALEQQLNKWSAAYHQQGHSPVTDDIYDQLQDKLRVWQSCRGLPDKTESQPIPGKGQFLHPVAHSGLKKLKDETALTRWMAGRKNLWVQPKVDGVAVTLVYHGGKLVQLLSRGNGVKGQNWTEKAPFISAIPQYIANAPALLTLQGELFLLMDGHQQAKSGGVNARSTVAGALMRKSPSPLLAQVGVFIWAWPDGPTTMKEKVALLQVMGFPFTAKYSEPVMSHLDVVQWRQFWFQAPLPFVTDGVVVRQEEEPAGRYWQATPGQWSMAWKYPPLQHIAEVKDIHFTLGRTGKGTVVLEVLPIKIDDKWIRRVNIGSVTRWKQWDIAPGDHITLALAGHGIPRLDNVVWRVHQRNTITAPNWDKFHQLSCFQRLPHGCEPQFLSRLIWLSGPGGLDIGGIGGGFWQELIHHELINDLVGWLLLTPEQIASIPGIGNARAEKIYQQFQRAKQQPFSRWLLALGFPQVVSVDAQWQVVLRRSLSEWATMAGIGQMRAKQIKHFLDHPDVQALADFLSTQKVVGFELTE
What is the function of this protein?
Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.
What are the official names of this protein?
DNA ligase B, Polydeoxyribonucleotide synthase [NAD(+)] B.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigB subfamily.
Protein: THII_ALISL
Sequence: MKFIVKPHPEVFVKSDSVRKRFIRILETNLRSIIQRDTKGVEVINRRDYIEVSGLDGTYRNQVLTAVTHTPGIHHTLEVKQTAFADMHDIYEQCLEMNREIIEGKTFCVRVKRRGTHPFTSIELERYVGGGLNQAVESAKVKLKNPDVTVKFEVENEKLNLVIARHKGLGGFPLGTQEDVLSLISGGFDSGVSSYLHIKRGSKVHYMFFNLGGPAHEIGVKQVSHFLWKKYGSSAKVKFIAVDFEPVVAEILEKVDDGQMGVILKRMFMRAGGMVAEKLGIQGMVTGEALGQVSSQTLTNLRHIDNVTDTLILRPLINWDKEDIINVARDIGTEDFAKTMPEYCGVISKKPTIKAEKLKLEKEEAKFDFSILDQVIYDARVMDIRAIEKESQEQAPEVEMVSELGSDVVVLDIRSAEEEDESPLIIEGVEVKHLPFFRIATQFGDLDQSKEYLLYCDHGVMSRLQALLLIENGYKNVKVYRP
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSRA_SALTY
Sequence: MQISHNTASPLICVQNIYKSYSGVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDGGTIDIAGVRCSHLTPLKAHQYGIYLVPQEPLLFPSLSVRENILFGLQGRQASTEKMQQLLKAMGCQLDPASAAGTLDVADRQIVEIMRGLMRDSRILILDEPTASLTPAETDRLFTRLQELLKKGVGIVFISHKLPEIRQLAHCVSVMRDGKIALFGKTHDLSTDEIIQAITPATQGVSLSANQKLWLELPGSRPQNERGATVLALESLTGEGFMNINLEVRAGEILGLAGLVGAGRTELAETLYGIRPVNAGRMLFNGQEINALTTQQRLQLGLVYLPEDRQSSGLYLDASLAWNVCSLTHNQKGFWIKPQRDNATLERYHRALNIKLNNAEQAARTLSGGNQQKVLIAKCLEASPQLLIVDEPTRGVDVSARSDIYQLLRSIAQQNVAVLFISSDLEEIEQMADRVYVMHQGELGGPALCGEEINVDTIMHVAFGEHGASEATC
What is the function of this protein?
Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Autoinducer 2 import ATP-binding protein LsrA, AI-2 import ATP-binding protein LsrA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. AI-2 autoinducer porter (TC 3.A.1.2.8) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TATC_ROTMD
Sequence: MATPDQDVRNRKINPEARMELKEHLREFRDRLIKAAIATIIAAIIGTVFLYQPFIEMISAPLQQINIETGRRANLNYGSVASPFDQLLKVGMYIGLVIASPVWLYQALRFLLPALHTKEKKYLFGFLTASIFAFACGVAISYFTLPGVVYALLKFTPVNESNYIDAGVYISFILKFVVTFSCAFIIPVILVGINMLGLIRGKTILKSWRWVVVLVAVIAALTAPGSDIMMMFVLMAPLLIFFFAAIGICMINDKRRDRKLAKLAQGSDEASLNTATSSEDLAKMGYFEEEKTS
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
What are the official names of this protein?
Sec-independent protein translocase protein TatC.
What is the protein family that this protein belongs to?
Belongs to the TatC family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS9_ECOL6
Sequence: MAENQYYGTGRRKSSAARVFIKPGNGKIVINQRSLEQYFGRETARMVVRQPLELVDMVEKLDLYITVKGGGISGQAGAIRHGITRALMEYDESLRSELRKAGFVTRDARQVERKKVGLRKARRRPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.