PharMolix/UniProtQA huggingface dataset:
Protein: UVRB_STRPI
Sequence: MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMGATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYADSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFRVEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQLAVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFFPDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVHQIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKNERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQRAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDITSLNKQERKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPEE_SYNE7
Sequence: MSADAPVWIDEVFEDRVRYGLRGQILWEETSPFQKITIVDTEHYGRGLLLDDCWMTAERCEVCYHEYLVHPPLTTAASIARVLVIGGGDGGTVREVLRYAEVEQVDLVEIDGRVVELSQEYLGAIGTAWADPRLNVKIGDGIAFVQTAPDASYDVILVDGSDPAGPAAGLFNREFYENCRRVLKPGGVFASQAESPDSFLAVHLEMIETLSAVFAEAKPYYGWVPMYPSGWWSWLYASDTPGQFQKPQSDRLAAIEPQVEIYNRDIHQAAFAQPNFVRRGLSARQG
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F16PA_BORPD
Sequence: MKRKTLTQYLVEQQRSANALGPEVRLLIEVVARACKAISHAVSKGALGGVLGSLESENVQGEVQKKLDVLSNEILLEANEWGGHLAAMASEEMETIHLIPNRYPKGEYLLLFDPLDGSSNIDVNVSIGTIFSVLHAPHRVAGAEEVCEQDFLQPGSQQVAAGYAVYGPQTMLVLTIGTGVVGFTLDREMGSWVLTHENMRVPEDTKEFAINMSNMRHWAPPVRRYIDECLAGTTGPLGKDYNMRWIASMVADVHRIMTRGGIFMYPWDAREPGKAGKLRLMYEANPMSMIIEQAGGAAIDGTRRILDIQPDKLHQRVSVILGSKNEVERVGRYHAEAAQAPA
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIKE_ECOLI
Sequence: MTLLNISGLSHHYAHGGFNGKHQHQAVLNNVSLTLKSGETVALLGRSGCGKSTLARLLVGLESPAQGNISWRGEPLAKLNRAQRKAFRRDIQMVFQDSISAVNPRKTVREILREPMRHLLSLKKSEQLARASEMLKAVDLDDSVLDKRPPQLSGGQLQRVCLARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQIVETQVVGEKLTFSSDAGRVLQNAVLPAFPVRRRTTEKV
What is the function of this protein?
Part of the ABC transporter complex NikABCDE involved in nickel import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Nickel import ATP-binding protein NikE.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NUP85_DANRE
Sequence: MEELDVEPSTTLVPAAGVLQKHLGFEWGPGDLLVYETNYKLRGSSSAGSPLVHVVRKDEDICSPILRKLFNESHLIFMGLQKIKEDAPSKNKKTQFVSISRNYRSVIRACMEELQQNAVTAQDGSLASQYGDQVSILLAIELIWNLCEVLFIEAAPAGSLLLHLLNWVRLHKSDVDTRAREVLQSENPTQHPAYWDVVTSLVLQGRMDEARQILSKQASLRMESSSVFKRMDTLLQTMPIFNPAGAQTLTEFDVKWRHWHEECDRCLQDHTFASSAELETLCKILLGDEDVILEQKDLMSTWYHFLVSRLLFTHPTIKPPDLHYYAQSSMNMFLGPRATPEPLDIILLSAFEFDLHQVIKDCSIALNNWWFVAHLTDLLDHCKLLQSHNLHFGSNLREFLVLEYASGLFTHHSLWQLAVDYLDHCPEFGRVYLELQIERVPLDTERKANKVLRICEDRQMSEQVRSICKIMAKRALRNNRLGSALSWSIRAKDAALATLISERFLQDYSNKGSFTDLDVLDNLGPAMLLSDRLTFLGKYREFHRLYGENRFSDAAKLLLSLMMAKIAPRSLWMTLLTDALPLLEQEEVIFTVDQTYELMSCLEELNSGTKDSNQMEQEEDLESTKTELLRVALARNLATAIVKEGTIET
What is the function of this protein?
Component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance (By similarity).  Involved in nephrogenesis (By similarity).
What are the official names of this protein?
Nuclear pore complex protein Nup85, 85 kDa nucleoporin, Nucleoporin Nup85, Pericentrin-1.
What is the protein family that this protein belongs to?
Belongs to the nucleoporin Nup85 family.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex. Nucleus membrane.
Protein: AATPA_ARATH
Sequence: MMMGNTFGSSLASLFFLWATIQQIFPNHLRIAIKEFLISTIQQLSFVQRFSDRFINFFSPYVEISFSQYEDYQFNHAFAAIETYLGAKATDKAKHLRASQVKESKGLVLKRDETKVRDEYEGGTVWWEMETDSTGYRTFKLTFHRRSRDIVTDSYIKYVFEEGKSIQAKSKQMKLFTNNPSSHWGTSKKSFWRYIDFEHPASFHTLAMDTKKKEEILNDLAAFSNGKEYYKKIGKAWKRGYLLHGPPGTGKSTMIAAMANHLNYSIYDLELTAIRNNSELRKLLTATSSKSIIVIEDIDCSLDLTGKRKKEKNLMTSREDGEQGTEEDKSFVTLSGLLNFIDGIWSACGQERIIIFTTNHFEKLDPALIRRGRMDMHIELSYCSFEAFKILAKNYLDLDTHPLFKKIESLLKETKIAPADVAENLMKKNTEIDADGSLKDLIQALEGKKKIHGAQVDEPKDKYTKKFYKAFCMSSKA
What are the official names of this protein?
AAA-ATPase At3g28600.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. BCS1 subfamily.
Protein: O16G_BACCE
Sequence: MEKQWWKESVVYQIYPRSFMDSNGDGIGDLRGIISKLDYLKELGIDVIWLSPVYESPNDDNGYDISDYCKIMNEFGTMEDWDELLHEMHERNMKLMMDLVVNHTSDEHNWFIESRKSKDNKYRDYYIWRPGKEGKEPNNWGAAFSGSAWQYDEMTDEYYLHLFSKKQPDLNWDNEKVRQDVYEMMKFWLEKGIDGFRMDVINFISKEEGLPTVETEEEGYVSGHKHFMNGPNIHKYLHEMNEEVLSHYDIMTVGEMPGVTTEEAKLYTGEERKELQMVFQFEHMDLDSGEGGKWDVKPCSLLTLKENLTKWQKALEHTGWNSLYWNNHDQPRVVSRFGNDGMYRIESAKMLATVLHMMKGTPYIYQGEEIGMTNVRFESIDEYRDIETLNMYKEKVMERGEDIEKVMQSIYIKGRDNARTPMQWDDQNHAGFTTGEPWITVNPNYKEINVKQAIQNKDSIFYYYKKLIELRKNNEIVVYGSYDLILENNPSIFAYVRTYGVEKLLVIANFTAEECIFELPEDISYSEVELLIHNYDVENGPIENITLRPYEAMVFKLK
What are the official names of this protein?
Oligo-1,6-glucosidase, Dextrin 6-alpha-D-glucanohydrolase, Oligosaccharide alpha-1,6-glucosidase, Sucrase-isomaltase, Isomaltase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_AZOPC
Sequence: MSRSLRKGPYINVKLEKKILLMNESKKKSVVKTWARASMISPDFVGCTIAVHNGNKFIPVYITENMVGHKLGEFSPTRQFRGHAGNKKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: MYO1_CAEEL
Sequence: MSLEHEKDPGWQYLKRSREQQLADQSRPYDSKKNVWIPDAEEGYIEGVIKGPGPKADTVIVTAGGKDVTLKKDIVQEVNPPKFEKTEDMSNLTFLNDASVLWNLRSRYAAMLIYTYSGLFCVVINPYKRLPIYTDSVARMFMGKRRTEMPPHLFAVSDQAYRYMLQDHENQSMLITGESGAGKTENTKKVICYFATVGASQKAALKEGEKEVTLEDQIVQTNPVLEAFGNAKTVRNNNSSRFGKFIRIHFNKHGTLASCDIEHYLLEKSRVIRQAPGERCYHIFYQIYSDFKPQLRDELLLNHPISNYWFVAQAELLIDGIDDTEEFQLTDEAFDVLKFSPTEKMDCYRLMSAHMHMGNMKFKQRPREEQAEPDGQDEAERACNMYGIDVDQFLKALVSPRVKVGTEWVSKGQNVDQVHWAIGAMAKGLYARVFHWLVKKCNLTLDQKGIDRDYFIGVLDIAGFEIFDFNSFEQLWINFVNEKLQQFFNHHMFVLEQEEYAREGIQWTFIDFGLDLQACIELIEKPLGIISMLDEECIVPKATDMTLAQKLTDQHLGKHPNFEKPKPPKGKQGEAHFAMRHYAGTVRYNVLNWLEKNKDPLNDTVVSVMKASKKNDLLVEIWQDYTTQEEAAAAAKAGGGRKGGKSGSFMTVSMMYRESLNKLMTMLHKTHPHFIRCIIPNEKKQSGMIDAALVLNQLTCNGVLEGIRICRKGFPNRTQHPDFVQRYAILAAKEAKSSDDMKTCAGAILQALINQKQLNDEQFRIGHTKVFFKAGVVAHIEDLRDDKLNQIITGFQSAIRWYTATADAGARRKQLNSYIILQRNIRSWCVLRTWDWFLLFGKLRPQLKCGKMAEEMIKMAEEQKVLEAEAKKAESARKSQEEAYAKLSAERSKLLEALELTQGGSAAIEEKLTRLNSARQEVEKSLNDANDRLSEHEEKNADLEKQRRKAQQEVENLKKSIEAVDGNLAKSLEEKAAKENQIHSLQDEMNSQDETIGKINKEKKLLEENNRQLVDDLQAEEAKQAQANRLRGKLEQTLDEMEEAVEREKRIRAETEKSKRKVEGELKGAQETIDELSAIKLETDASLKKKEADIHALGVRIEDEQALANRLTRQSKENAQRIIEIEDELEHERQSRSKADRARAELQRELDELNERLDEQNKQLEIQQDNNKKKDSEIIKFRRDLDEKNMANEDQMAMIRRKNNDQISALTNTLDALQKSKAKIEKEKGVLQKELDDINAQVDQETKSRVEQERLAKQYEIQVAELQQKVDEQSRQIGEYTSTKGRLSNDNSDLARQVEELEIHLATINRAKTAFSSQLVEAKKAAEDELHERQEFHAACKNLEHELDQCHELLEEQINGKDDIQRQLSRINSEISQWKARYEGEGLVGSEELEELKRKQMNRVMDLQEALSAAQNKVISLEKAKGKLLAETEDARSDVDRHLTVIASLEKKQRAFDKIVDDWKRKVDDIQKEIDATTRDSRNTSTEVFKLRSSMDNLSEQIETLRRENKIFSQEIRDINEQITQGGRTYQEVHKSVRRLEQEKDELQHALDEAEAALEAEESKVLRLQIEVQQIRSEIEKRIQEKEEEFENTRKNHQRALESIQASLETEAKSKAELARAKKKLETDINQLEIALDHANKANVDAQKNLKKLFDQVKELQGQVDDEQRRREEIRENYLAAEKRLAIALSESEDLAHRIEASDKHKKQLEIEQAELKSSNTELIGNNAALSAMKRKVENEVQIARNELDEYLNELKASEERARKAAADADRLAEEVRQEQEHAVHVDRQRKSLELNAKELQAKIDDAERAMIQFGAKALAKVEDRVRSLEAELHSEQRRHQESIKGYTKQERRARELQFQVEEDKKAFDRLQENVEKLQQKIRVQKRQIEEAEEVATQNLSKFRQIQLALENAEERAEVAENSLVRMRGQVVRSATNK
What is the function of this protein?
Muscle contraction.
What are the official names of this protein?
Myosin-1, Myosin heavy chain D, MHC D.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril. Note=Thick filaments of the myofibrils.
Protein: MURG_HELAH
Sequence: MKVALTGGGTGGHLSIAKALAIELEKQGVEAIYLGSTYGQDKEWFEDSPLFSECYFFNTQGVVNKSFFKKIGSLFLQAKAALKAKEILKKHQITHTISVGGFSAGPASFASLLNKIPLYIHEQNAIKGSLNRYLSPKAKAVFSSYAFKDKGNHIVTSYPVQNVFFDHARTRTEIKHILFIGGSQGAKAINEFALFNAPKLTKQGIEITHICGPNSYERVRFFYQELGLLDKIVLFAFHNNIIEVMQKADLCVSRAGASSVWELCANGLPTIFIPYPFASNNHQYHNVLEFEKENLCYVVPQNELLPKKLFEVIRKLNQKDEQGHKNLTIISNKLQQKIAKDGAKTIIERILSA
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RNPA_ACIBY
Sequence: MMALYSFSTDLRIRCAADYKSVFDGALFKVHQPHFLFLAKLTEQPNSRLGIVVAKKKVRRAHERNRIKRLARESFRLHQPKFGSDIDVVVMPKVGIETITNAELYQQLDFAWQKLQRLAKKHSKVVPTSQN
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: HPRK_PARP8
Sequence: MDTSSINAQSIFDDNAAALKLSWLTGHEGWERGFSAETVATATSSADLVGHLNLIHPNRIQVLGEAETNYYQRQSDEDRSRHMAELIALEPPFLVVAGGVAAPPELVLRCTRSSTPLFTTPMSPAAVIDSLRLYMSRILAPRATLHGVFLDILGMGVLLTGDSGLGKSELGLELISRGHGLVADDAVDFVRLGPDFVEGRCPPLLQNLLEVRGLGLLDIKTIFGETAVRRKMKLKLIVQLVRRPDGEFQRLPLESQTVDVLGLPISKVTIQVAAGRNLAVLVEAAVRNTILQLRGIDTLRDFMDRQRLAMQDPDSQFPGKLI
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: RECR_XANC5
Sequence: MSTLLEQLIEAFRVLPGVGQKSAQRMAYHVLEREREGGRRLAAALGNAVEKVGHCVQCRDFTESEICTICASSSRDRQQLCVVESPADRLAIEHATGYRGLYFILQGRLSPLDGIGPRELGLDRLGERLAAGEVTEMIIATNATVEGEATAHYLAQLARQHAVRPSRLAQGMPLGGELEYVDRGTLSHAFGTRSEVL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: PDXS_THEON
Sequence: MGKLHVIEAKGTERLKRGFARMVKGGVIMDVTNAEQARIAEEAGAVSVMALHKVPADIRKAGGVARMAPIEKIQEIMDAVTIPVMAKVRIGHVAEARVLEALGVDMIDESEVLTPADPFFHIDKREFNVPFVCGARNLGEAVRRIWEGSAMIRTKGEAGTGNIVEAVRHVRLVADNIRLIQRMTDEQVYAVAEKFAEPYLRLARQIREISGLPEQILENEPVYGHYTYREIVDGLYKILLEIKKLGRLPVVNFAAGGVATPADAALMMQMGMDGVFVGSGIFKSSTPEKMARAIVEAVNHWDEPDVIAAISKEIGEPMKGLEIEELEVRLEERGV
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: NADD_NEIG2
Sequence: MKKIGLFGGTFDPIHNGHFHIARAFADEIGLDAVVFLPAGGPYHKDAASASAADRLAMVELATAEDARFAVSDCDIVRESATYTFDTVQIFRRQFPSAQLWWLMGSDSLLKLHTWKKWQLLVRETNIAVAMRQGDSLHQTPRELHAWLGNALQDGSVRILSAPMHNVSSTEIRRNLSAAGVSDGIPPAAARYIRKHGLYEK
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: YI142_YEAST
Sequence: MFTNTLAAGLSSGIDFRIVAPSFVTMQVLLDALCNNLSIPFGPNVLFTKSPTAMAPTNADKRAFSALSSVTWSPNICTLILNLLSFVRLTLLAYLMATFHPLFYCSALVF
What are the official names of this protein?
Putative uncharacterized protein YIL142C-A.
Protein: SPART_HUMAN
Sequence: MEQEPQNGEPAEIKIIREAYKKAFLFVNKGLNTDELGQKEEAKNYYKQGIGHLLRGISISSKESEHTGPGWESARQMQQKMKETLQNVRTRLEILEKGLATSLQNDLQEVPKLYPEFPPKDMCEKLPEPQSFSSAPQHAEVNGNTSTPSAGAVAAPASLSLPSQSCPAEAPPAYTPQAAEGHYTVSYGTDSGEFSSVGEEFYRNHSQPPPLETLGLDADELILIPNGVQIFFVNPAGEVSAPSYPGYLRIVRFLDNSLDTVLNRPPGFLQVCDWLYPLVPDRSPVLKCTAGAYMFPDTMLQAAGCFVGVVLSSELPEDDRELFEDLLRQMSDLRLQANWNRAEEENEFQIPGRTRPSSDQLKEASGTDVKQLDQGNKDVRHKGKRGKRAKDTSSEEVNLSHIVPCEPVPEEKPKELPEWSEKVAHNILSGASWVSWGLVKGAEITGKAIQKGASKLRERIQPEEKPVEVSPAVTKGLYIAKQATGGAAKVSQFLVDGVCTVANCVGKELAPHVKKHGSKLVPESLKKDKDGKSPLDGAMVVAASSVQGFSTVWQGLECAAKCIVNNVSAETVQTVRYKYGYNAGEATHHAVDSAVNVGVTAYNINNIGIKAMVKKTATQTGHTLLEDYQIVDNSQRENQEGAANVNVRGEKDEQTKEVKEAKKKDK
What is the function of this protein?
May be implicated in endosomal trafficking, or microtubule dynamics, or both.  Participates in cytokinesis (PubMed:20719964).
What are the official names of this protein?
Spartin, Spastic paraplegia 20 protein, Trans-activated by hepatitis C virus core protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Midbody. Note=Transiently associated with endosomes (PubMed:19580544). Colocalized with IST1 to the ends of Flemming bodies during cytokinesis (PubMed:20719964).
Protein: RUVC_FRATM
Sequence: MVILGIDPGSRITGFGVIKVQDNKIYYVASGCIRITEITTPKRLKQIADGITQIINIYAPTEAAIEQIFMFQNPMGAIKLGQARGVAMCTLAINNLEVSEYSAKQIKQAVVGTGGAAKSQVQHMVQSLLGLSKKPPEDAADALAIAICHYHSSKSLAKISGASRVSQKRIK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: TPIS_SYNY3
Sequence: MRKIIIAGNWKMHKTQAEAQAFLQGFKPLIEDAAESREVVLCVPFTDLSGMSQQLHGGRVRLGAQNVHWEASGAYTGEISAAMLTEIGIHYVVIGHSERRQYFGETDETANLRVLAAQKAGLIPILCVGESKAQRDAGETEQVIVDQVKKGLVNVDQSNLVIAYEPIWAIGTGDTCAATEANRVIGLIREQLTNSQVTIQYGGSVNANNVDEIMAQPEIDGALVGGASLEPQSFARIVNFQP
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_SHEPA
Sequence: MPVITLPDGSKREFAHSVSTLDVAADIGPGLAKACIAGRVNGELKDACDLIETDSDLSIITAKDEEGVEILRHSCAHLLGHAIKQLFPETKMAIGPVIDNGFYYDIDLDHKLTQEDIDALEKRMAELAKTNYAVDKRVVSWQEARDTFESRGEVYKMAILDENIPKDSTPALYHHEEYIDMCRGPHVPNMKFCQNFKLMSVAGAYWRGNSDNKMLQRVYGTAWADKKALKVHLNRLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWSLFLELEKFIRQKLGQYTYQEVKGPLMMDRVLWERSGHWDKYSEAMFTTSSENREYAVKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGCCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQVQQEVSACIKMVYDTYETFGFNSIVVKLSTRPEKRIGDDEMWDRAEEALKQALKANDIEFEILPGEGAFYGPKIEFTLHDCLDRAWQCGTVQLDYALPGRLGATYVAEDNSRQTPVMIHRAILGSLERFLGILIEEYAGKFPAWLSPVQVVVMNITDKQSDYVDEVVNLFKEHGIRATKDLRNEKIGFKIREHTLRRVPYLLVVGDQEMENKEVAVRTREGVDLGKMQIEEFATKLKNQISLRSLNLLED
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_GEODF
Sequence: MDQRILNVELRSKTGKGISRQLRRSESIPGVVYGKGIESVSVSLKTKELSNAIAGEGGRNHILTLKGGGSLDGQMVIVADLLQDSLKGLPLHVDLHKINLADKIKVKVKVNLVGTAAGVKEGGLLDFAMHEIEIECLPSHIPEHLDVDVTSLTLGHSIHIGDLKELPGIKVLGDPKASIISVLGRAKEEAAPVAEA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: RF3_LEGPL
Sequence: MSDFYQDFNKRRTFAIISHPDAGKTTVTEKLLLFGGAIQLAGTVKGRKADRHATSDWMEMEKERGISITTSVMQFVHNQHVINLLDTPGHEDFSEDTYRTLTAVDSALMVIDVAKGVEERTVKLMEVCRLRDTPIMTFINKLDREGREPIDLLDEVESVLGIQCAPITWPVGMGKRFKGIYHRYQDIIYLYQQGSNAKKIDATQIKGLDNPQLDELIGDSAKELREEIELVRGASNEFNLQDYLAGKMTPVYFGSAINNFGIKELLDDFVEYAPGPQPRATQERVVSPNEETFSGFVFKIQANMDPKHRDRIAFVRVCSGSYKKGMKLSHLRIGKEVQISNALTFMAGDRSHTELALAGDIIGLHNHGTIRIGDTFTQGEQLKFTGIPNFAPELFRLVRLRDPLKSKALLKGLIELSEEGATQVFRPLNSNQLILGAVGILQFDVVAHRLKYEYKVDCIYESVNIACARWVYSDDDKAMSEFRTKAYDYLALDGGDMLMYLAPTKVNLTMAEERYPKIKFCATREH
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSPG5_RAT
Sequence: MGRAGGGGPGWGPPPVLLLLGVTLVLTAGAVPAREAGSAIEAEELVRSGLAWESRANDTREEAGLPAAGEDETSWTERGSELAAVGPGVGPEETLEASAAVTGTAWLEADGTGLGGVTAEAGSGDAQTLPATLQAPDEALGSSTMPPAIPEATEASGPPSPTLRDKPSLVPELPKEIPLEVWLNLGGSTPDPQRPEPTFPLQGTLETQPASDIIDIDYFEGLDSEGRGTDMGRFPGSPGTSENHPDTEGETPSWSLLDLYDDFTPFDESDFYPTTSFYDDLEEEEEEEEDKDAVGGGDLEDESDLLLPSQKPGVGPGTGQPTSRWHAVPPQHTLGMVPGGSISLRPRPGDPGKDLATSENGTECRVGFVRHNGSCRSVCDLFPSYCHNGGQCYLVENIGAFCRCNTQDYIWHKGMRCESIITDFQVMCVAVGSAALVLLLLFMMTVFFAKKLYLLKTENTKLRRTNKFRTPSELHNDNFSLSTIAEGSHPNVRKLCDTPCVSSPHARALAHCDNIVCQDDPSAPHKIQEALKSRLKEEESFNIQNSMSPKLEGGKGDQDDLEVNCLQNNLT
What is the function of this protein?
May function as a growth and differentiation factor involved in neuritogenesis.  May induce ERBB3 activation.
What are the official names of this protein?
Chondroitin sulfate proteoglycan 5, Acidic leucine-rich EGF-like domain-containing brain protein, Neuroglycan C.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Synaptic cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Cell surface. Note=In neurons, localizes to synaptic junctions. Also detected in the endoplasmic reticulum and the Golgi (By similarity). Partially enriched in lipid rafts (PubMed:11929867).
Protein: ATPG_LEVBA
Sequence: MAESIHDVQRRINSTKATRQITSAMHMVSTAKLNKIQKQAVGYQDYVSKVKAVVMHLSQSHLLDNSSSSLQSNRPVKKTAYLVITSDRGMVGSYNSSVLRDTNAFIKERTPNPDDYMVLAVGGTGADFYKHRGVNVAYEYRGVSDVPEFNEVREIVKTVTTMFNNEVFDELFVCYNHFVNRISSRFRAEKMLPVDKETMSTDAAKDTQAAPLTAEYDTEPSEEEVLQVVLPQYAESLVYGAILDAKTAEHASSTNAMQSATDNADDLIATLQLHYNRARQAAITTEITEITGGQEALNN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: FB340_ARATH
Sequence: MTRKYIYIYIYIILKVRARVGANNKTLINNQSHLIEMRNTLMLSDLPGDLLEEILCRVPATSLKQLRSTCKQWNNLFNNGRFTRKHLDKAPKDFQNLMLSDSRVFSMSVSFHGIPSVEATCELSLIDSFSSFEDKFEISQVFHCDGLLLCTDADNTRIVVWNPCTGKTRWIEPNNRCYYYAFGSYLDKSYGNSYKILSYSGYGYENQELAIYEINSQSWRFLDVTRDCILERYTDYGVSLKGHTYWFASDEKEKNLSVFLVSFDYTTERFRRLRLPYQCPDYNTASLSVVREEKLAVLLQRENTSRTEIWVTSRIGETKVVSWSMVLAVDFPSELFILSGISFLVDAEKKFVVCCDNYFGEDEYDTKNLVHIVGENNKVREVNFGVSESSWPFLFNYVPSLIQIWEGVGGKRKRVE
What are the official names of this protein?
Probable F-box protein At5g47300.