PharMolix/UniProtQA huggingface dataset:
Protein: IL17F_RAT
Sequence: MKGSCETTMVKSLLLLMLGFAIISSGAARRNPKVGLSALQKAGNCPPLEDNSVRVDIRIFNQNQGISVPRDFQNRSSSPWDYNITRDPDRFPSEIAEAQCRHSGCINAQGQEDGSMNSVPIQQEILVLRREPQGCSNSFRLEKMLIKVGCTCVTPIVHHAA
What is the function of this protein?
Effector cytokine of innate and adaptive immune system involved in antimicrobial host defense and maintenance of tissue integrity.  IL17A-IL17F signals via IL17RA-IL17RC heterodimeric receptor complex, triggering homotypic interaction of IL17RA and IL17RC chains with TRAF3IP2 adapter through SEFIR domains.  This leads to downstream TRAF6-mediated activation of NF-kappa-B and MAPkinase pathways ultimately resulting in transcriptional activation of cytokines, chemokines, antimicrobial peptides and matrix metalloproteinases, with potential strong immune inflammation.  IL17A-IL17F is primarily involved in host defense against extracellular bacteria and fungi by inducing neutrophilic inflammation.  As signature effector cytokine of T-helper 17 cells (Th17), primarily induces neutrophil activation and recruitment at infection and inflammatory sites.  Stimulates the production of antimicrobial beta-defensins DEFB1, DEFB103A, and DEFB104A by mucosal epithelial cells, limiting the entry of microbes through the epithelial barriers.  IL17F homodimer can signal via IL17RC homodimeric receptor complex, triggering downstream activation of TRAF6 and NF-kappa-B signaling pathway.  Via IL17RC induces transcriptional activation of IL33, a potent cytokine that stimulates group 2 innate lymphoid cells and adaptive T-helper 2 cells involved in pulmonary allergic response to fungi.  Likely via IL17RC, promotes sympathetic innervation of peripheral organs by coordinating the communication between gamma-delta T cells and parenchymal cells.  Stimulates sympathetic innervation of thermogenic adipose tissue by driving TGFB1 expression.  Regulates the composition of intestinal microbiota and immune tolerance by inducing antimicrobial proteins that specifically control the growth of commensal Firmicutes and Bacteroidetes.
What are the official names of this protein?
Interleukin-17F, IL-17F.
What is the protein family that this protein belongs to?
Belongs to the IL-17 family.
What are the subcellular locations of this protein?
Secreted.
Protein: 3MGA_BACSU
Sequence: MTWHEVNDVIVITLPEIFDMNANLGYLTREKNECMYEIENNIITKVIAIGEIRSLVQVSVINNKQMIVQFLNDSRPVEQWKREEIVKYIHEWFDLDNDLTPFYEMAKADPLLKMPARKFYGLRVIGIPDLFEALCWGVLGQQINLAFAYSLKKQFVEAFGDSIEWNGKKYWVFPPYERIARLTPTDLADIKMTVKKSEYIIGIARLMASGELSREKLMKMNFKDAEKNLIKIRGIGPWTANYVLMRCLRFPTAFPIDDVGLIHSIKILRNMNRKPTKDEILEISVPWKEWQSYATFYLWRVLY
What is the function of this protein?
Is involved in the adaptive response to alkylation damage in DNA caused by alkylating agents.  Catalyzes the hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.
What are the official names of this protein?
DNA-3-methyladenine glycosylase, 3-methyladenine-DNA glycosidase.
What is the protein family that this protein belongs to?
Belongs to the alkylbase DNA glycosidase AlkA family.
Protein: LIN28_DROME
Sequence: MENVQLENGLERRTTSQSSTSSANPANLASPTEECGCVRLGKCKWFNVAKGWGFLTPNDGGQEVFVHQSVIQMSGFRSLGEQEEVEFECQRTSRGLEATRVSSRHGGSCQGSTYRPRINRRTRRMRCYNCGEFANHIASECALGPQPKRCHRCRGEDHLHADCPHKNVTQSHSNSKSISNNSSSSAAQEKSEEAT
What are the official names of this protein?
Protein lin-28 homolog.
What is the protein family that this protein belongs to?
Belongs to the lin-28 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_LEPBL
Sequence: MENQKNFLTTAPYKGTRDFYPEEMRLRNWMFSIMRETVLSFGYEEYDGPILESFDLYKAKSGEEIVERQLYDFIDKGERRVAIRPEMTPTLARMVAGNLRNLPRPVRWFSIPNLWRYEQPGKGRLREHWQLNVDLFGVDTHRAELEILLMADSILKKFGAPTGSYQIKVSHRKLLDSFLKNSLKLSDHQVHGVSKLLDKKSKISPETFEAEIKPLLNNFNEQFSLIETYLASNLETVSTIPGIDPDSIHFIRNLFQELGELGIDKQLVFDPSIIRGFDYYTGCIFEVFDTNPENRRSLYGGGRYDNLIGLFSKEQLSGIGFGLGDVTLKSFLENHNLIPDLSREKTLFLPIMDESIFVDTFKLSKELRENGILTETMLDSAKIGKQIQVAEKKGYRYVLFLGESEIRTETVQIKDLVSGEQKSLPRKGLSDILKKDFRL
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURI_CORGL
Sequence: MIERPVPGADAPIGIFDSGVGGLTVARTIIDQLPHESVIYIGDTANGPYGPLPIAKVREHAIRIADELVERGCKMIVIACNTASAAFLRDARERYSVPVVEVILPAVRRAVASTRNGKVGVIGTVGTINSGAYQDLFSASPSIVVNAVACPRFVDFVERGITSGRQILNIAQDYLEPLQAEGVDTLVLGCTHYPLLSGVIQLAMGDHVSLVSSAEETAKDVLRILSQQDLLADPDMHPEPSYSFESTGDPEIFAQLSRRFLGPIVSQVRQNEG
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: LMA2_LOCMI
Sequence: AHRFAAEDFGALDTA
What is the function of this protein?
Myotropic peptide.
What are the official names of this protein?
Lom-AG-myotropin-2, Accessory gland myotropin II, Lom-AG-myotropin II.
Protein: OMCA_CHLPN
Sequence: MKKAVLIAAMFCGVVSLSSCCRIVDCCFEDPCAPSSCNPCEVIRKKERSCGGNACGSYVPSCSNPCGSTECNSQSPQVKGCTSPDGRCKQ
What is the function of this protein?
In elementary bodies (EBs, the infectious stage, which is able to survive outside the host cell) provides the structural integrity of the outer envelope through disulfide cross-links with the large cysteine-rich periplasmic protein and the major outer membrane porin.  It has been described in publications as the Sarkosyl-insoluble COMC (Chlamydia outer membrane complex), and serves as the functional equivalent of peptidoglycan (By similarity).
What are the official names of this protein?
Small cysteine-rich outer membrane protein OmcA, Small-CRP, 9 kDa cysteine-rich lipoprotein, 9KD-CRP.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Note=The protein moiety probably penetrates into the periplasm.
Protein: TM35B_RAT
Sequence: MLVSLGALRVLLGIFFTLTGAAKLFQVSAPVSQQMKALFEQFAEVFPLKVLGYQPDPISYQAAVGWLELLAGLLLVVGPPVLQQISNVLLILLMMGAVFTLVVLEESLSTYIPAVVCLGLLLLLDSCQFLVRTKGAVRCRNKIPGALGNPRK
What are the official names of this protein?
Transmembrane protein 35B, ZMYM6 neighbor protein.
What is the protein family that this protein belongs to?
Belongs to the DoxX family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL3_PECCP
Sequence: MIGLVGKKVGMTRIFTEDGVSIPVTVIEIEANRVTQVKDLANDGYRAVQVTTGAKKANRVTKPEAGHFAKAGVEAGRTLREFRLSEGEEFTVGQSISVEIFADVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKKMAGQLGNERVTVQSLDVVRVDAERNLLLVKGAVPGATGSDLIVKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: NEUV_CHICK
Sequence: MAEPSLPLSFLCLLALSSACYIQNCPRGGKRALGDTALRQCLPCGPGNRGRCFGPGICCGAELGCYLGTAETRRCAEEDYMPSPCQAGGQPCGSDGRCAANGVCCSADTCAMDAVCLEEGSEQAEEAAEKNLTVLDGAAGDLLLRLMHLANRQQQGKQPGL
What is the function of this protein?
Vasotocin is an antidiuretic hormone.
What are the official names of this protein?
Vasotocin-neurophysin VT.
What is the protein family that this protein belongs to?
Belongs to the vasopressin/oxytocin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RBCR_TRIV2
Sequence: MSDLPFTLDQLRILKAIAVEGSFKRAADSLYVSQPAVSLQVQNLERQLDVPLFDRGGRRAQLTEAGHLLLNYGEKILSLCQETCRAIEDLQNLQGGTLIVGASQTTGTYLLPKMIGMFRQKYPDVAVQLHVHSTRRTAWSVANGQVDLAIIGGEIPGELTESLEIIPYAEDELALILPVFHPFTKQETIQKEDLYKLQFITLDSQSTIRKVIDQVLSRSEIDTRRFKIEMELNSIEAIKNAVQSGLGAAFVSTSAIAKELQMGVLHCTPIDGVVIKRTLWLIFNPNRYRSKAAEAFSQEILPQFATPDWNQDVLKLVQKKLVVNVLDAAIPNTSDDG
What is the function of this protein?
Trans-acting transcriptional regulator of RuBisCO genes (rbcL and rbcS) expression.
What are the official names of this protein?
Probable RuBisCO transcriptional regulator.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: KHSE_STAHJ
Sequence: MTEQLHLKIPASTANLGVGFDSIGMAIDKYLHLYVKRIEEEEWEFTYLNSELDSLPKNKDNYVFKVAQQVASKYNVKLPSLSVEMRSDIPLARGLGSSASALVGALYIANYFGNIQLSKYELLQLATEIEGHPDNVAPTIYGGLLAGFYNPDTKETNVAHIDVPDVDIILTIPPYELKTEDSRNVLPDQFSHKRAVQSSAISNTMLCALIQHNYGLAGKMMSQDGFHEPYRQHLISEFKEVKAIAQQYDAYATVISGAGPTILTMSPKEKSGQLVRALRKAVTTCHSELATINEIGVVEEIVYPS
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEPT_SALPK
Sequence: MDKLLERFLHYVSLDTQSKSGVRQVPSTEGQWKLLRLLKQQLEEMGLVNITLSEKGTLMATLPANVEGDIPAIGFISHVDTSPDFSGKNVNPQIVENYRGGDIALGIGDEVLSPVMFPVLHQLLGQTLITTDGKTLLGADDKAGVAEIMTALAVLKGNPIPHGEIKVAFTPDEEVGKGAKHFDVEEFGAQWAYTVDGGGVGELEFENFNAASVNIKIVGNNVHPGTAKGVMVNALSLAARIHAEVPADEAPETTEGYEGFYHLASMKGTVDRAEMHYIIRDFDRKQFEARKRKMMEIAKKVGKGLHPDCYIELVIEDSYYNMREKVVEHPHILDIAQQAMRDCHITPEMKPIRGGTDGAQLSFMGLPCPNLFTGGYNYHGKHEFVTLEGMEKAVQVIVRIAELTAKRGQ
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STLP3_ORYSI
Sequence: MKRRHWSHPSCGLLLLVAVFCLLLVFRCSQLRHSGDGAAAAAPDGGAGRNDGDDVDERLVELAAVDPAAMAVLQAAKRLLEGNLARAPERHRDVALRGLREWVGKQERFDPGVMSELVELIKRPIDRYNGDGGGGGEGEGRRYASCAVVGNSGILLAAEHGELIDGHELVVRLNNAPAGDGRYARHVGARTGLAFLNSNVLSQCAVPRRGACFCRAYGEGVPILTYMCNAAHFVEHAVCNNASSSSSGAADATAAAPVIVTDPRLDALCARIVKYYSLRRFARETGRPAEEWARRHEEGMFHYSSGMQAVVAAAGVCDRVSVFGFGKDASARHHYHTLQRRELDLHDYEAEYEFYRDLESRPEAIPFLRQRDSGFRLPPVSFYR
What is the function of this protein?
Possesses sialyltransferase-like activity in vitro.  Transfers sialic acid to the glycoprotein asialofetuin.  The transferred sialic acid is linked to galactose of Gal-beta-1,3-GalNAc through alpha-2,6-linkage.
What are the official names of this protein?
Sialyltransferase-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 29 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: S35B1_XENLA
Sequence: MSSAPASGGLRLLVCFLGVFVCYFYYGILQETITRRTYGEGEKQEKFRFALSLVFVQCIVNALFAKLLIQCFDSGKTDRTQSWLYSACSLSYLGAMVSSNSALQFVNYPTQVLGKSCKPIPVMLLGVTLLRKKYPLTKYLCVLLIVFGVALFMYKPKTGSGDGDHTVGYGELLLLLSLTLDGLTGVSQDYMRAHFQTGSNHMMLSINLWSSLFLGAGIVLTGELWDFLSFTERYPSIVYNIVLFSLTSALGQTFIFMTVVYFGPLTCSIITTTRKFFTILASVILFSNPISSIQWVGTLLVFLGLGLDATYGKGSKKPSH
What is the function of this protein?
Probable sugar transporter.
What are the official names of this protein?
Solute carrier family 35 member B1, Endoplasmic reticulum nucleotide sugar transporter 1.
What is the protein family that this protein belongs to?
Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PA1B3_MOUSE
Sequence: MSGEGENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWRELFSPLHALNFGIGGDSTQHVLWRLENGELEHIRPKIVVVWVGTNNHSHTAEQVTGGIKAIVQLVNKLQPQARVVVLGLLPRGQHPNPLREKNRQVNELVRAALAGYPRAHFLDADPGFVHSDGTISHHDMYDYLHLSRLGYTPVCRALHSLLLRLLAQDQGQGIPLPETAS
What is the function of this protein?
Alpha1 catalytic subunit of the cytosolic type I platelet-activating factor (PAF) acetylhydrolase (PAF-AH (I)) heterotetrameric enzyme that catalyzes the hydrolyze of the acetyl group at the sn-2 position of PAF and its analogs and modulates the action of PAF.  The activity and substrate specificity of PAF-AH (I) are affected by its subunit composition.  Both alpha1/alpha1 homodimer (PAFAH1B3/PAFAH1B3 homodimer) and alpha1/alpha2 heterodimer(PAFAH1B3/PAFAH1B2 heterodimer) hydrolyze 1-O-alkyl-2-acetyl-sn-glycero-3-phosphoric acid (AAGPA) more efficiently than PAF, but they have little hydrolytic activity towards 1-O-alkyl-2-acetyl-sn-glycero-3-phosphorylethanolamine (AAGPE).  Plays an important role during the development of brain.
What are the official names of this protein?
Platelet-activating factor acetylhydrolase IB subunit alpha1, PAF acetylhydrolase 29 kDa subunit, PAF-AH 29 kDa subunit, PAF-AH subunit gamma, PAFAH subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family. Platelet-activating factor acetylhydrolase IB beta/gamma subunits subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VC12_SWPVK
Sequence: MNKYNNYRAIYFLYKVILRIHNTEYISGTLQRSIQNITPTTSSYTYCDNSKRRRHRFRDTEILKAMGSKMRRKLF
What are the official names of this protein?
Uncharacterized protein C12.
Protein: AGO3_BOMMO
Sequence: MADPGKGRGRSLALLQALKKSQMMDSPSQSESQSPESTPEQSTAPSTIASATPSTSGVSIGGRGRAAALMLAKMQQKPGSTTPAIFVPPSSTSAPTAGTGRGFKLLQNLQASQKASSQIASSQVTSSAQSDIKDLTEKMSETSVSAQASSVAKNKYFREVKDTPPVVKKGETGVPIEVTCNYIYLNFKENIVFEYEVKFEPDQDYKHLRFKLLNEHIEHFKEKTFDGTTLYVPHELPDAVRNLVSTNPYDQSKVNVSIIFRRTRRLSEMIHIYNVMFKCIMKDLKLIRFGRQHYNEHAAIQIPQHKLEVWPGYVTAVDEYEGGLMLTLDSTHRVLRTQTVLSLIKEVVQTEGANWKRKMTDILIGASVMTTYNKKLFRVDTIDDKMSPRSTFEKTEKGETVQISFIDYYKKNYGIEIMDWDQPLLISRDTKRMPGSDTPTDFMICLIPELCQLTGLTDDQRSNFRLMKDVATYTRITPNQRHAAFKKYIESVMKNETAKSRLAGWGLSIAPETVNLTARTLPPETLYFGDNVRVPGKPNAEWNSEVTKHSVMQAVDIMRWVLLFTQRDKQVAMDFLSTLKRNCRPMGIMVSDAELVPLANDRTDTYVLALKKCITSSVQLVVAICSTKRDDRYAAIKKVCCADNPVPSQVINARTLMNTNKIRSITQKILLQLNCKLGGTLWSISIPFKSAMIVGIDSYHDPSRRNRSVCSFVASYNQSMTLWYSKVIFQEKGQEIVDGLKCCLVDALTHYLRSNGQLPDRIIIYRDGVGDGQLKLLQQYEIPQMKICFTILGSNYQPTLTYVVVQKRINTRIFLKSRDGYDNPNPGTVVDHCITRRDWYDFLIVSQKVTQGTVTPTHYVVVYDDSGITPDQCQRLTYKMCHLYYNWPGTVRVPAPCQYAHKLSYLVGQCVHAQPSDVLVDKLFFL
What is the function of this protein?
Endoribonuclease that plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity (PubMed:19460866).  Plays an essential role in meiotic differentiation of spermatocytes, germ cell differentiation and in self-renewal of spermatogonial stem cells (PubMed:19460866, PubMed:25558067).  Its presence in oocytes suggests that it may participate in similar functions during oogenesis in females (PubMed:18191035).  Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons (PubMed:19460866, PubMed:25558067).  Directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements (PubMed:19460866, PubMed:25558067).  Strongly prefers a have adenine at position 10 of their guide (g10A preference) (PubMed:24757166, PubMed:25558067).  Plays a key role in the piRNA amplification loop, also named ping-pong amplification cycle: antisense piRNA-bound Siwi and sense piRNA-bound Ago3 reciprocally cleave complementary transcripts, to couple the amplification of piRNAs with the repression of transposable elements (PubMed:25558067).
What are the official names of this protein?
Piwi-like protein Ago3, BmAGO3.
What is the protein family that this protein belongs to?
Belongs to the argonaute family. Piwi subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Component of the meiotic nuage, also named P granule, a germ-cell- specific organelle required to repress transposon activity during meiosis.
Protein: PSBL_GOSBA
Sequence: MTQSNPNEQNVELNRTSLYWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: PCR12_ARATH
Sequence: MYGNGPVFKAEGTSFRDQPYAEQLPQGLWTTGLCDCHEDAHICVQTAIMPCVSFAQNVEIVNRGTIPCMNAGLIHLALGFIGCSWLYAFPNRSRLREHFALPEEPCRDFLVHLFCTPCAICQESRELKNRGADPSIGWLSNVEKWSREKVTPPIVVPGMIR
What is the function of this protein?
May be involved in heavy metals transport.
What are the official names of this protein?
Protein PLANT CADMIUM RESISTANCE 12, AtPCR12.
What is the protein family that this protein belongs to?
Belongs to the cornifelin family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PEP6_ARATH
Sequence: MEVNGEEERRSRREDEEKEDYYYSLLNSPCSVCNKFVQAILKCLGLESSSIPPSSSSSSPSLVEEEDSGTETVEETGFMARITAVLRRRPRPPPYSSGRPGQNN
What is the function of this protein?
Elicitor of plant defense.
What are the official names of this protein?
Elicitor peptide 6.
What is the protein family that this protein belongs to?
Belongs to the brassicaceae elicitor peptide family.
Protein: KCS12_ARATH
Sequence: MDLLFLFFSLLLSYLFFKIWKLIDSKQDKDCYILDYQCHKPTDDRMVSTQFSGEIIYRNQNLGLTEYKFLLKAIVSSGIGEQTYAPRLVFEGREERPSLQDGISEMEEFYVDSIGKLLERNQISPKDIDILVVNVSMLSSTPSLASRIINHYKMRDDVKVFNLTGMGCSASLISVDIVKNIFKSYANKLALVATSESLSPNWYSGNNRSMILANCLFRSGGCAILLTNKRSLRKKAMFKLKCMVRTHHGAREESYNCCIQAEDEQGRVGFYLGKNLPKAATRAFVENLKVITPKILPVTELIRFMLKLLIKKIKIRQNPSKGSTNLPPGTPLKAGINFKTGIEHFCIHTGGKAVIDGIGHSLDLNEYDIEPARMTLHRFGNTSASSLWYVLAYMEAKKRLKRGDRVFMISFGAGFKCNSCVWEVVRDLTGGESKGNVWNHCIDDYPPKSILNPYLEKFGWIQDEDPDTFKVPDAFM
What are the official names of this protein?
3-ketoacyl-CoA synthase 12, KCS-12, Very long-chain fatty acid condensing enzyme 12, VLCFA condensing enzyme 12.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: SDR2B_ARATH
Sequence: MAEESPRYAIVTGGNRGIGFEICRQLANKGIRVILTSRDEKQGLEAVETLKKELEISDQSIVFHQLDVSDPVSVTSLAEFVKTHFGKLDILINNAGVGGVITDVDALRAGTGKEGFKWEETITETYELAEECIKINYYGPKRMCEAFIPLLQLSDSPRIINVSSFMGQVKNLVNEWAKGILSDAENLTEVRIDQVINQLLNDLKEDTAKTKYWAKVMSAYVVSKAGLNAYTRILAKKHPEIRVNSVCPGFVKTDMNFKTGILSVEEGASSPVRLALLPHQESPSGCFFDRKQVSEF
What is the function of this protein?
Aldehyde reductase that catalyzes the reduction of the aldehyde carbonyl groups on saturated and alpha,beta-unsaturated aldehydes with more than 5 carbons (PubMed:21169366).
What are the official names of this protein?
Short-chain dehydrogenase/reductase 2b, AtSDR2b.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: LPRB_MYCBO
Sequence: MRRKVRRLTLAVSALVALFPAVAGCSDSGDNKPGATIPSTPANAEGRHGPFFPQCGGVSDQTVTELTRVTGLVNTAKNSVGCQWLAGGGILGPHFSFSWYRGSPIGRERKTEELSRASVEDINIDGHSGFIAIGNEPSLGDSLCEVGIQFSDDFIEWSVSFSQKPFPPPCDIAKELTRQSIANSK
What are the official names of this protein?
Putative lipoprotein LprB.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: NDOA_PSEFL
Sequence: DVLGVTVEGKDLALYEVEGEIYATDDLCTHGAARMSDGYLEGREIECPLHQGRFDVCTGRALCAPVTENIKTYAVKIENLRVMIDLS
What is the function of this protein?
Component of the naphthalene dioxygenase (NDO) multicomponent enzyme system which catalyzes the incorporation of both atoms of molecular oxygen into naphthalene to form cis-(1R,2S)-dihydroxy-1,2-dihydronaphthalene.  Functions as an intermediate electron transfer protein via a specific interaction with iron sulfur protein components (ISP) (NdoB and NdoC).
What are the official names of this protein?
Naphthalene 1,2-dioxygenase system, ferredoxin component.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase ferredoxin component family.
Protein: ATPE_ORYSJ
Sequence: MKLNLYVLTPKRIIWDCEVKEIILSTNSGQIGVLPNHAPINTAVDMGPLRIRLLNDQWLTAVLWSGFARIVNNEIIILGNDAELGSDIDPEEAQQALEIAEANVSRAEGTKELVEAKVALRRARIRVEAVNWIPPSN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, chloroplastic, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: TYRO3_MOUSE
Sequence: MALRRSMGWPGLRPLLLAGLASLLLPGSAAAGLKLMGAPVKMTVSQGQPVKLNCSVEGMEDPDIHWMKDGTVVQNASQVSISISEHSWIGLLSLKSVERSDAGLYWCQVKDGEETKISQSVWLTVEGVPFFTVEPKDLAVPPNAPFQLSCEAVGPPEPVTIYWWRGLTKVGGPAPSPSVLNVTGVTQRTEFSCEARNIKGLATSRPAIVRLQAPPAAPFNTTVTTISSYNASVAWVPGADGLALLHSCTVQVAHAPGEWEALAVVVPVPPFTCLLRNLAPATNYSLRVRCANALGPSPYGDWVPFQTKGLAPARAPQNFHAIRTDSGLILEWEEVIPEDPGEGPLGPYKLSWVQENGTQDELMVEGTRANLTDWDPQKDLILRVCASNAIGDGPWSQPLVVSSHDHAGRQGPPHSRTSWVPVVLGVLTALITAAALALILLRKRRKETRFGQAFDSVMARGEPAVHFRAARSFNRERPERIEATLDSLGISDELKEKLEDVLIPEQQFTLGRMLGKGEFGSVREAQLKQEDGSFVKVAVKMLKADIIASSDIEEFLREAACMKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASRIGENPFNLPLQTLVRFMVDIACGMEYLSSRNFIHRDLAARNCMLAEDMTVCVADFGLSRKIYSGDYYRQGCASKLPVKWLALESLADNLYTVHSDVWAFGVTMWEIMTRGQTPYAGIENAEIYNYLIGGNRLKQPPECMEEVYDLMYQCWSADPKQRPSFTCLRMELENILGHLSVLSTSQDPLYINIERAEQPTESGSPEVHCGERSSSEAGDGSGVGAVGGIPSDSRYIFSPGGLSESPGQLEQQPESPLNENQRLLLLQQGLLPHSSC
What is the function of this protein?
Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including TULP1 or GAS6.  Regulates many physiological processes including cell survival, migration and differentiation.  Ligand binding at the cell surface induces dimerization and autophosphorylation of TYRO3 on its intracellular domain that provides docking sites for downstream signaling molecules.  Following activation by ligand, interacts with PIK3R1 and thereby enhances PI3-kinase activity.  Activates the AKT survival pathway, including nuclear translocation of NF-kappa-B and up-regulation of transcription of NF-kappa-B-regulated genes.  TYRO3 signaling plays a role in various processes such as neuron protection from excitotoxic injury, platelet aggregation and cytoskeleton reorganization.  Also plays an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3.
What are the official names of this protein?
Tyrosine-protein kinase receptor TYRO3, Etk2/tyro3, TK19-2, Tyrosine-protein kinase DTK, Tyrosine-protein kinase RSE, Tyrosine-protein kinase TIF.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. AXL/UFO subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: CSPL1_SORBI
Sequence: MTMELESQEVVVETTTAAAAARAASAAHVRTTVALRLLAFAASLAAAVVVATNRQERWGITVTFKMFAVWEAFVAINFACAAYALLTAVFVKKLVSKHWLHHMDQFTVNLQAASTAGAGAVGSVAMWGNEPSGWYAVCRLYRLYCDRGAVSLALAFVAFVAFGVASSLSRYPRAPPPPAPR
What are the official names of this protein?
CASP-like protein UU-1, SbCASPLUU-1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.