PharMolix/UniProtQA huggingface dataset:
Protein: SCDA_STAAS
Sequence: MINKNDIVADVVTDYPKAADIFRSVGIDFCCGGQVSIEAASLEKKNVDLNELLQRLNDVEQTNTPGSLNPKFLNVSSLIQYIQAAYHEPLREEFKNLTPYVTKLSKVHGPNHPYLVELKETYDTFKNGMLEHMQKEDDVDFPKLIKYEQGEVVDDINTVIDDLVSDHIATGQLLVKMSDLTSSYEPPIEACGTWRLVYQRLKALEVLTHEHVHLENHVLFKKVS
What is the function of this protein?
Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions.
What are the official names of this protein?
Iron-sulfur cluster repair protein ScdA.
What is the protein family that this protein belongs to?
Belongs to the RIC family. ScdA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_COXBU
Sequence: MPRVKRGVTARARHKKVLTKAKGYYGARSRVFRVAKQAVIKAAQYAYRDRKQRKRQFRALWIVRINAAAREHGLSYSRLINGLMKASVAIDRKNLAELAVYDKAAFGKLAEKAKQALGG
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: TRI13_FUSSP
Sequence: MFLSLCLMVLALYLLYKWALPKPISSIPYNPPALQSLFGDIPAMIQGTKANNQTHMDWIIQQMKNHESPIIQLFLSPLQRPTVILADFRETQDIMLRRKDFDRSTNIRGLLEDVIPDHHIYEQTNSVFRTHRKLVQDVMLPSFIQKVAGPAFHSNIMRLVRVWDLKAQIADGSPFLATQDIQGAVLDAVYSFAFGSYYKSSTTLPKIEKLEKWNGNAENSSRNAPQSDKPFDFPDVAFDDLINATIDLAKAPQGLQGSPIAKLQAKVTMNMPHFRRVRKIRDDFLRGSLKSAVSKLPSEGGKSDSQAVTSAVEQMVLRETALAQTENRSPNYFSTMMQGELFGLILGGFDTTSTTTLWGLKFLTDNASVQKRLRQALQSSFTKAKAENRSPTFQELAVARIPYLEAVIEEILRCAGATPALQRLAKVDTQILGYHIPKGTDVLFLTHGPSVWTPGFEIDESRRSQTCQAAGEKKDQCWESHDISKFKPERWLGQKLPSNNREKDTDATETAEEFDGLAGPTLAFGLGTRGCFGRRLGYQQLKTSITILIWNFELLPCPQELSSYRTIEGLTSMPEHSYISLAKVDLTTT
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the core gene cluster that mediates the biosynthesis of trichothecenes, a very large family of chemically related bicyclic sesquiterpene compounds acting as mycotoxins, including T2-toxin (PubMed:11352533, PubMed:12135578).  The biosynthesis of trichothecenes begins with the cyclization of farnesyl diphosphate to trichodiene and is catalyzed by the trichodiene synthase TRI5 (PubMed:3800398).  Trichodiene undergoes a series of oxygenations catalyzed by the cytochrome P450 monooxygenase TRI4 (PubMed:7651333).  TRI4 controls the addition of four oxygens at C-2, C-3, C-11, and the C-12, C-13-epoxide to form the intermediate isotrichotriol (PubMed:16917519).  Isotrichotriol then undergoes a non-enzymatic isomerization and cyclization to form isotrichodermol (PubMed:2317042).  During this process, the oxygen at the C-2 position becomes the pyran ring oxygen and the hydroxyl group at C-11 is lost (PubMed:2317042).  More complex type A trichothecenes are built by modifying isotrichodermol through a series of paired hydroxylation and acetylation or acylation steps (PubMed:11352533).  Isotrichodermol is converted to isotrichodermin by the acetyltransferase TRI101 (PubMed:10583973).  TRI101 encodes a C-3 transacetylase that acts as a self-protection or resistance factor during biosynthesis and that the presence of a free C-3 hydroxyl group is a key component of Fusarium trichothecene phytotoxicity (PubMed:10583973).  A second hydroxyl group is added to C-15 by the trichothecene C-15 hydroxylase TRI11, producing 15-decalonectrin, which is then acetylated by TRI3, producing calonectrin (PubMed:9435078, PubMed:8593041).  A third hydroxyl group is added at C-4 by the cytochrome P450 monooxygenase TRI13, converting calonectrin to 3,15-diacetoxyspirpenol, which is subsequently acetylated by the acetyltransferase TRI7 (PubMed:12135578, PubMed:11352533).  A fourth hydroxyl group is added to C-8 by the cytochrome P450 monooxygenase TRI1, followed by the addition of an isovaleryl moiety by TRI16 (PubMed:12620849, PubMed:14532047).  Finally, the acetyl group is removed from the C-3 position by the trichothecene C-3 esterase TRI8 to produce T-2 toxin (PubMed:12039755).
What are the official names of this protein?
Cytochrome P450 monooxygenase TRI13, Core trichothecene cluster (CTC) protein 13.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: GRPE_STAA9
Sequence: MTNKDESVEKNTESTVEETNIKQNIDDSVEQAEESKGHLQDEAIEETSDENVIEEIDPKDQKINELQQLADENEEKYLRLYAEFENYKRRIQKENEINKTYQAQRVLTDILPAIDNIERALQIEGDDETFKSLQKGVQMVHESLINALKDNGLEVIKTEGEAFDPNIHQAVVQDDNPDFESGEITQELQKGYKLKDRVLRPSMVKVNQ
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYP4B_MAGO7
Sequence: MLSLLETKIIEPFMVVRQTLAPLRLSRWQIFKHMTRILIFSSNTRTIIFCVLMSLVGYIVSRIIWGRQEKYPDHGLPIVKTNDYHFDNIVAEGKRLYPNQAFMGINKRYKFVIYPSSSWEELKRIPEQTASIMDFQHVCNSGEWSLVGGETHELVKTITAELTRSLPARVPNRQQDAKMTFDTIIGHCPEEKGFNLLMTSLEIIAKINACTFVGRELGANKSWVTAVVYSPLWVYFAVTLCNATPDILRPLLRPLFFLPALRNYWNMQKLLKPKLDREMETFRQTDDKRKLLVPKSDQDLPFTHFLLSRYTEAAATIKQLVIDYIQVSYTSTPTTASALFHALWELAQHPEAAEVMRRELATVMIDGNLPKTHLQELKRMDSFLRESFRLHPITRFTLQRYVKEPFQLSDGSRIPPGVMAVVDAQEINRSPEIWENPDEFDMDRFYRLREISGNDNRYHFVTTSSNSPGWGDGTQACPGRFFATSTLKIVMAHIVMNYDVSLRKVAPLKSQPLVNGSYSPDDSVEIFFKSRNVE
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of a tyrosine-derived cytochalasan acting as a fungal signal recognized by resistant rice plants and leads to avirulence in Pi33 resistant rice cultivars (PubMed:18433432).  The first step in the pathway is catalyzed by the hybrid PKS-NRPS ACE1, assisted by the enoyl reductase RAP1, that are responsible for fusion of the tyrosine precursor and the polyketide backbone (PubMed:29142718).  The polyketide synthase module (PKS) of ACE1 is responsible for the synthesis of the polyketide backbone and the downstream nonribosomal peptide synthetase (NRPS) amidates the carboxyl end of the polyketide with the tyrosine precursor (PubMed:29142718).  Because ACE1 lacks a designated enoylreductase (ER) domain, the required activity is provided the enoyl reductase RAP1 (PubMed:29142718).  Reduction by the hydrolyase ORFZ, followed by dehydration and intra-molecular Diels-Alder cyclization by the Diels-Alderase ORF3 then yield the required isoindolone-fused macrocycle (Probable).  A number of oxidative steps catalyzed by the tailoring enzymes identified within the cluster, including cytochrome P450 monooxygenases CYP1 to CYP4, the FAD-linked oxidoreductase OXR2 and the short-chain dehydrogenase/reductase OXR1, are further required to afford the final cytochalasans that confer avirulence and which have still to be identified (Probable).  The monooxygenase CYP1 has been shown to be a site-selective C-18 hydroxylase whereas the function of CYP3 is the site-selective epoxidation of the C-6/C-7 olefin that is present in some intermediate compounds (PubMed:31644300).  Finally, SYN2 and RAP2 are not required for avirulence in Pi33 resistant rice cultivars (PubMed:18433432).
What are the official names of this protein?
Cytochrome P450 monooxygenase CYP4, ACE1 cytochalasan biosynthesis cluster protein CYP4.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MFA4_PORG3
Sequence: MKKYLLYASLLTSVLLFSCSKNNPSEPVEDRSIEISIRVDDFTKTGETVRYERNQGSAAERLITNLYLLLFDQSGANPAKYYIAGNTFSGGIWLPDDMKVKLDMTQSEAGERKVYVVANVDNAVKTALDAVANESDLQTVKRTTAMPWSTDIASPFLMSGNKTHDFLANRLLDNVPLVRAIAKVELNISLSEKFQIVPIIVNGSLSEFKFRYVNFDKETYVVKPTTKPDNLISSANGVWPQITDWTVWGASLNTSPAPDAGTGYTLDANGKVTALRIVTYLNERDSKGATVEVALPRVDDGTLPPPEFGPELYRLPLPDKILRNHWYKYEVEI
What is the function of this protein?
Tip subunit of the minor fimbriae.  These filamentous pili are attached to the cell surface; they mediate biofilm formation, adhesion onto host cells and onto other bacteria that are part of the oral microbiome (PubMed:19589838, PubMed:26001707).  They play an important role in invasion of periodontal tissues and are recognized as major virulence factors (Probable).
What are the official names of this protein?
Minor fimbrium tip subunit MfA4, Immunoreactive 32 kDa antigen.
What is the protein family that this protein belongs to?
Belongs to the bacteroidetes fimbrillin superfamily. FimA/Mfa1 family.
What are the subcellular locations of this protein?
Fimbrium. Cell outer membrane. Note=Targeted to the outer membrane as a palmitoylated precursor. The lipid modification is no longer present after proteolytic processing to the mature form.
Protein: RL5_LACP7
Sequence: MTRLKEIYKNEIMAGMQKKFGYKNEMQIPKLDKIVINMGVGEAKDNAKALEAAVKDMEIIAGQKAVITKARKSVANFKLREGVAIGCKVTLRGEKMYEFADRLINLALPRVRDFRGVNPNAFDGRGNYALGVKEQLIFPEIEYDKVDKVRGMDVIFVTTAKTDEEARELLTLFGMPFSK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: SYAC_PONAB
Sequence: MDSTLTASKIRQRFIDFFKRNEHTYIHSSATIPLDDPTLLFANAGMNQFKPIFLNTIDPSHPMAKPSRAANTQKCIRAGGKHNDLDDVGKDVYHHTFFEMLGSWSFGDYFKELACKMALELLTQEFGIPIERLYVTYFGGDEAAGLEPDLECKQIWQNLGLDDTKILPGNMKDNFWEMGDTGPCGPCSEIHYDRIGGRDAAHLVNQDDPNVLEIWNLVFIQYNREADGILKPLPKKSIDTGMGLERLVSVLQNKMSNYDTDLFVPYFEAIQKGTGARPYTGKVGAEDADGIDMAYRVLADHARTITVALADGGRPDNTGRGYVLRRILRRAVRYAHEKLNASRGFFATLVDVVVQSLGDAFPELKKDPDMVKDIINEEEVQFLKTLSRGRRILDRKIQSLGDSKTIPGDTAWLLYDTYGFPVDLTGLIAEEKGLVVDMDGFEEERKLAQLKSQGKGAGGEDLIMLDIYAIEELRARDLEVTDDSPKYNYHLDSSGSYVFENTVATVMALRREKMFVEEVSTGQECGVVLDKTCFYAEQGGQIYDEGYLVKVDDSSEDKTEFTVKNAQVRGGYVLHIGTIYGDLKVGDQVWLFIDEPRRRPIMSNHTATHILNFALRSVLGEADQKGSLVAPDRLRFDFTAKGAMSTQQIKKAEEIANEMIEAAKPVYTQDCSLAAAKAIQGLRAVFDETYPDPVRVVSIGVPVSELLDDPSGPAGSLTSVEFCGGTHLRNSSHAGAFVIVTEEAIAKGIRRIVAVTGAEAQKALRKAGSLKKPLSVMEAKVKAQTAPNKDVQREIADLGEALATAVIPQWQKDELRETLKSLKKVMDDLDRASKADVQKRVLEKTKQLIDSNPNQPLVILEMESGASAKALNEALKLFKMHSPQTAAMLFTVDNEAGKITCLCQVPQNAANRGLKASEWVQQVSGLMDGKGGGKDVSAQATGKNVGCLQEALQLATSFAQLRLGDVKN
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, cytoplasmic, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15A_DROME
Sequence: MVRMNVLADALKCINNAEKRGKRQVLLRPCSKVIIKFLTVMMKHGYIGEFEIVDDHRSGKIVVNLTGRLNKCGVISPRFDVPINDIEKWTNNLLPSRQFGYVVLTTSGGIMDHEEARRKHLGGKILGFFF
What are the official names of this protein?
40S ribosomal protein S15Aa.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: 1433_LILLO
Sequence: MSPAEPSREENVYMAKLAEQAERYEEMVEFMEKVARTVDTEELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRGNEDHVALIKDYRGKIEAELSKICDGILKLLDSHLVPSSTAPESKVFYLKMKGDYHRYLAEFKSGAERKEAAESTLLAYKSAQDIALAELAPTHPIRLGLALNFSVFYYEILNSPDRACNLAKQAFDEAISELDTLGEESYKDSTLIMQLLRDNLTLWTSDINEEAGDEIKEASKAVEGQ
What are the official names of this protein?
14-3-3-like protein.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
Protein: PTHP_STRMU
Sequence: MASKDFHIVAETGIHARPATLLVQTASKFASDITLDYKGKAVNLKSIMGVMSLGVGQGADVTITAEGADADDAIAAINETMTKEGLA
What is the function of this protein?
P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes.  Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources.  P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity (By similarity).
What are the official names of this protein?
Phosphocarrier protein HPr, Histidine-containing protein.
What is the protein family that this protein belongs to?
Belongs to the HPr family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ABL6_LEPMJ
Sequence: MKVEVMSSHRVHPEHKKASEETAILPVIDSWYCYWRTLAAIYLFDAYSGPELYTDLRQSLSKTLDDFPQLAGTLDNCNIQVEDKSGRSVRRTRVTWGGNTLGGEFIEAKTNARVRSLLPPSIQNISSFAWDRSDRTLRPLFPATLPETSGIRVQVTSFKCGGFGIALDMDHALADAHTVGLFIGHWSAIHTRMFTSTTTFPSQISLPNVMFNPQFVEKKVHETDNTYGSKMVMLDRARELPTRRPDLRDKSSQRTMQGNMFKPPPKPSAGVPYLLHFSASEYERITRGIQQATASPQITDQVAFVSFLWAALNKARARCSVGQAVDLHLPTSFRWTLGLPEGLIGSPLVAVMMDGGPDGEVCYTDPVVLATIITKTLERYTEDALLAIVYDASLRDSPASMLRGFERRERMEFTSGVGFGSDKLSFGCHSPVFVGPIILPVDNLFIMAEGMRTSEAHSSKWYKHGANIFVSLPQDVFRALLADPALINVELLGDI
What is the function of this protein?
Acyltransferase; part of the gene cluster that mediates the biosynthesis of abscisic acid (ABA), a phytohormone that acts antagonistically toward salicylic acid (SA), jasmonic acid (JA) and ethylene (ETH) signaling, to impede plant defense responses (PubMed:31034868).  The first step of the pathway catalyzes the reaction from farnesyl diphosphate to alpha-ionylideneethane performed by the alpha-ionylideneethane synthase abl3 via a three-step reaction mechanism involving 2 neutral intermediates, beta-farnesene and allofarnesene (By similarity).  The cytochrome P450 monooxygenase abl1 might then be involved in the conversion of alpha-ionylideneethane to alpha-ionylideneacetic acid (By similarity).  Alpha-ionylideneacetic acid is further converted to abscisic acid in 2 steps involving the cytochrome P450 monooxygenase abl2 and the short-chain dehydrogenase/reductase abl4, via the intermediates 1'-deoxy-ABA or 1',4'-trans-diol-ABA, depending on the order of action of these 2 enzymes (By similarity).  Abl2 is responsible for the hydroxylation of carbon atom C-1' and abl4 might be involved in the oxidation of the C-4' carbon atom (By similarity).  The acyltransferase abl6 seems not essential for the biosynthesis of ABA, but it may acetylate ABA as part of the synthesis of another ABA-related molecule (PubMed:31034868).
What are the official names of this protein?
Acyltransferase abl6, Abscisic acid biosynthesis cluster protein 6.
What is the protein family that this protein belongs to?
Belongs to the plant acyltransferase family.
Protein: KHSE_VIBA3
Sequence: MDVVVYAPASIGNVSVGFDVLGAAVSPVDGTLLGDRVMVKAGDEPFSLKTAGSFVSKLPTETKENIVYDCWVVFSRELDKKGISVKSLEMTLEKNMPIGSGLGSSACSIVAALDALNRFHGQPLNETELLALMGEMEGKISGGIHYDNVAPCYLGGVQLMLEELGIISQEVPCFDDWYWVMAYPGIKVSTAEAREILPSQYRRQDVIAHGRHLAGFIHACHSGQPELAAKMIKDVIAEPYREKLLPGFADARKYATSAGALATGISGSGPTLFSICKEQDVAERVARWLEQNYVQNEEGFVHVCRLDKQGSIVTGSEL
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPS_STRSY
Sequence: MIVGHGIDLQEMEAIESARIKHQGFPKKILTEKEFERYQSLSGRRQLEYLAGRWSAKEALTKALGTGIGKIGFHDIEILNTSKGVPYVTKSPFDGNIWLSISHSGNFVQASVILEEKDD
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA_SALG2
Sequence: MDKFRVQGPTTLQGEVTISGAKNAALPILFAALLAEEPVEIQNVPKLKDVDTSMKLLSQLGAKVERNGSVHIDASQVNVFCAPYDLVKTMRASIWALGPLVARFGQGQVSLPGGCTIGARPVDLHITGLEQLGATIKLEEGYVKASVEGRLKGAHIVMDKVSVGATVTIMCAATLAEGTTIIENAAREPEIVDTANFLVTLGAKIAGQGTDRITIEGVERLGSGVYRVLPDRIETGTFLVAAAISRGKILCRNAQPDTLDAVLAKLRDAGADIEVGEDWISLDMHGKRPKAVNVRTAPHPAFPTDMQAQFTLLNLVAEGTGFITETVFENRFMHVPELSRMGARAEIESNTVICHGIETLSGAQVMATDLRASASLVLAGCIAEGTTIVDRIYHIDRGYERIEDKLRALGANIERVKGE
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TCAA_STAEQ
Sequence: MSQCPNCGHQVKDDTSQCPNCGQLLTKKKKRKIKDQSSQSSNENSTNIRLRKIVPIGISVFILILIIVLFFLLRNYNSPNAQAKILVNAVDNNDSQKVATLLSTKNKKVDDVEAQQYINYVKKEVGIKKYIRDINNTVDKLNKSNSSVASYIQTKSGQDVLKISKNGTKYLIFDNMSFTAPTKKPIIKPKVETKYEFRTSGKKKTVIAEANKNTPLGEFIPGTYHLPAKKITENGTFNGHLNFDFRESHSETVDVAEDYDQSFINIKFKGANKLSDKSEKVQINDRTFTYSHSKEFGPYPKTKDITISATGKAKGKTFSSETKTISADDLKDNTKVTLEFDSDKINSYVEKKEKEENSLKNKLTEFFTGYATAMNSAFNMNDFNFISSYFKKNSSIYTSMKSNFQNRTNVTMISPQVLSVHRNGHTVRTTIQHIDHIGNYINKDYELEIDNDDSNMQLVKEL
What is the function of this protein?
Plays a major role in decreasing resistance to glycopeptide antibiotics.
What are the official names of this protein?
Membrane-associated protein TcaA.
What is the protein family that this protein belongs to?
Belongs to the TcaA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: UN112_CAEEL
Sequence: MAHLVEGTSIIDGKWQLPILVTDLNIQRSISVLGNLNVGGLMLELVSECDVERDWSDHALWWPEKRRWLQHTRSTLDQNGITAETQLEFTPMHKEARIQLPDMQMIDARVDFSVNSFKATKKLCRDLGIRYSEELSLKRYIPPEDLRRGTSDADNMNGPLSMRPGEESVGPMTLRKAAPIFASQSNLDMRRRGQSPALSQSGHIFNAHEMGTLPRHGTLPRGVSPSPGAYNDTMRRTPIMPSISFSEGLENEQFDDALIHSPRLAPSRDTPVFRPQNYVEKAAINRGWLDSSRSLMEQGIFEGDIILLRFKFMNFFDLNPKYDPVRINQLYEQAKWSILLDEFDHTEEEATLFAALQLQATLQRDSPEPEENNKDDVDILLDELEQNLDAAALNRRSDLTQVPELADYLKYMKPKKLAAFKGFKRAFFSFRDLYLSYHQSSSDVNSAPLGHFSLKGCEVSQDVSVGQQKYHIKLLLPTAEGMIDFILKCDSEHQYARWMAACRLASRGKSMADSSYQQEVESIKNLLKMQSGNGNENGNSNTASRKAAAVKLPNDFNVDEYISSKYVRRARSKQQIQQRVSDAHGNVRQLTATEAKLQYIRAWQALPEHGIHYFIVRFRNARKAELVAVAVNRLAKLNMDNGESLKTWRFANMKKWHVNWEIRHLKIQFEDEDIEFKPLSADCKVVHEFIGGYIFLSMRSKEHSQNLDEELFHKLTGGWA
What is the function of this protein?
Component of an integrin containing attachment complex, which is required for muscle development and maintenance (PubMed:22253611).  Probable regulator of cell-extracellular matrix adhesion (PubMed:10893272).  Required during initial muscle assembly to form dense bodies and M-lines (PubMed:10893272).
What are the official names of this protein?
Protein unc-112, Mitogen-inducible mig-2 protein-like, Uncoordinated protein 112.
What is the protein family that this protein belongs to?
Belongs to the kindlin family.
Protein: METE_METCA
Sequence: MAVTHSLGFPRIGAGRELKRAVEACWAGRTGPAELAQTGRELRERHWMIQSGSGIDLVPVGDFAWYDQMLNMTALLGAVPRRFGFQADALSLDQYFQLARGNAEQPAMEMTKWFDTNYHYIVPEFDRETGFGPGTEWLFDEVEEAKALRLNPKPVLIGPLTYLHLGKERQAGFSRLELLPRLLPAYAAILRRLHASGVPWVQMDEPILGMDLPPEWLEAFAPAYAALAEAGPKLLLATYFASVAEHAVWLKSSAVAGLHIDAVRAPEQVADFLKDFPADKVLSLGLIDGRNVWRTDLRRALEQAESAGAVLGERLWLAPSCSLLHVPQDLSLETSLNPEIKDWLAFAVQKLEELAVIDKGLRLGRQAVAAELAERDRLLQTRAQSPLIHDPGVKRRLEGLSDADFRRHSPFAERSPLQRERLRLPPFPTTTIGSFPQTPKIRAARAAHRRGELNGDAYRDAMRAAIREAVYKQESLGLDLLVHGEAERNDMVEYFGERLAGYAFTKHGWVQSYGSRCVKPPIIYGDVARPEPMTVEWIGYAQSLTKKPVKGMLTGPVTMLQWSFARDDQPRAVTALQIALAIRDEVADLEAAGVAAIQIDEPAFREGLPLKAADRADYLDWAVKAFRLASCGVADDTQIHTHMCYSEFGDILPAIAELDADVITIETCRSAMDLLEAFGAFGYPNDIGPGVYDIHSPRVPAGAEIRALLEKAAAAVDPERLWVNPDCGLKTRQWPEAEQALANMVEAARAMRRAESLAGSAA
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: YBEY_XYLFT
Sequence: MTRGPIFLNVGISYGLPRTKLPAAVSFRKWVAATLQGRIRKADLAIRIVDEKEGRALNYHYRNKDYATNVLSFPAQLPEPFPKALKIPLLGDIVMCAPVIAREATEQGKSLSAHYAHLTVHGTLHLLGWNHEDHQEADAMEQLEREILANLGISDPYLGEY
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BR1A_RANBO
Sequence: FLPILASLAAKFGPKLFCLVTKKC
What is the function of this protein?
Antibacterial activity against Gram-positive bacterium S. aureus and Gram-negative bacterium E. coli.  High antifungal activity against C. albicans and a strong hemolytic activity.
What are the official names of this protein?
Brevinin-1BYa.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
Protein: LIPB_JANMA
Sequence: MSVPQQPLILQRGLEAYETTFAAMRAFTDARTAATADELWIVEHPPVFTLGLAADPSHVLDPHQIPVVETDRGGEVTYHGPGQVVIYLLLDLRRHKADARLFARELVNKIEQSVIDTLAAYNLACERKPGAPGIYMSDGPAQGAKIAALGLKIRGNGCTYHGVSLNVAMDLTPFTWINPCGYEDLATIDMQSLGAQTTLAEVQNALANRLSTSLSR
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.