PharMolix/UniProtQA huggingface dataset:
Protein: FTSH_TRICV
Sequence: MNDNKNNTVRNLLIGIALLSGISLTAKKFDLIGVQGSESGKNINQVNPNVISSKMTYGRFLEYLEMGWVNQVDLYDNSRNAIVQASSPELGNRPQTIRVEIPVGASQLIQKLKEYNIDFDAHPAEQKNIFVNILSNILLPIIFITGLVYLFQNSENFGGGSGQSPMSLGKSTARFERRPDTGVSFKDIAGIDEAKTEFEEIVSFLKEPDKYTIVGAKIPKGILLVGPPGTGKTLLAKAIANEADVPFFSVAGSEFVEMFIGIGAARVRDLFKKASENAPCIVFIDEIDAVGRERGAGVGGGNDEREQTLNQLLTEMDGFKENKGVIVVGATNRADILDAALLRPGRFDRQVTVNLPDRLGRVGILKVHARNKPLGEDVSLVQLANRTPGFSGADLANLLNEAAILATRYKKSSITKNEVNEAADRIIGGIAGAPMEDTKNKRLIAYHEVGHAITGSVLKSHDEVEKITLTPRGGAKGLTWFTPEEDQSLLSRSALLARIITTLGGRAAEQVIFGEPEVTTGASSDLQQVTNLARQMVTRFGMSNIGPLALEDESTGQVFLGGNMASGSEYAENIADRIDDEVRKIITYCYEKAIEIVLDNRVVIDLIVEKLLDKETMDGDEFRELLSTYTILPNKNIPYVSKFN
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein; Stromal side.
Protein: RL22_ALIF1
Sequence: MEAIAKHRFAGISPQKARLVADQVRGKSVDQALEILTFSNKKAAVLVKKVLESAIANAEHNEGADIDDLNVAKIFVDEGPIMKRIMPRAKGRADRILKRSSHITIVVADR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: IPT_PANAY
Sequence: MRGNVYLLWGATTTGKTAFSVSVAKERGWSVIALDRFQGYHEISTGSGAPTNNELEKTERIYITPQRGLADGIITAKDYNYWLKSRVLSLPEGKSDFIIEGGSVSLLKEMVSDEFWADFLWEIKIFRAPSKDVFIKRAKRRITDMLHPEDGRPSIMDEVSSFFMNHKTIHPLEDIDGYRTIIDYCRCKKIGFDKLKIMTTDQEKIIISGIAEEYYAHALWQEQETPCFPHSWSRRW
What is the function of this protein?
Transfers dimethylallyl groups to AMP as part of the biosynthesis of cytokinin phytohormones.
What are the official names of this protein?
Adenylate dimethylallyltransferase, Dimethylallyl transferase, Isopentenyl transferase.
What is the protein family that this protein belongs to?
Belongs to the isopentenyl transferase family.
Protein: Y1090_BRUSU
Sequence: MTIRTLFNAILLSTTLLAAPSLAETPKEGGTLVYASNAGPGTLDPHMGNSLVELEIAHQIYEGLVTIDANYNTATMLAESYVLSEDSKTLTFKLRKGVKFHDGSDMKSDDVLASFERYAKVSPNAKVLDIVDHYETPDDYTFVIHLKEVNAAFLDTLKSPVYPFSIIPAEQKDKPARELDIIGTGPFKLGEWKRDSHLYLEKFADYVADKGKPASGYAGEKKVYVDKVRVNFLSETNSRVAAIQTGEAQVTTQLTADATKKLQNAPGVKPLEIIPFCQQYLIVNTQQAPTNNSAIRKALRTAVNAEDILVVSGEAATMDPSMSYPGGAYYSKENAEPYYNQNNPDEAAKMLADAGYKGEELVLLTNSNYDYMRDSIVLLAEQLQAAGFKARVEMTDWATNSTAMQTGSGKWNVSTTSFCSNPLLGPQQWQSVVYLFPQVKSDALMDTAYKKFFTSLKLEDRRAAWLDIEKHILDEAYMIKISNRASGRAYRPDDIGGYPEYYMNFFWNVWLKKQ
What is the function of this protein?
Probably part of an ABC transporter complex that could be involved in peptide import.
What are the official names of this protein?
Putative peptide-binding periplasmic protein BRA1090/BS1330_II1082.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 5 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: O6C75_HUMAN
Sequence: MRNSTAVTDFILLGLTSDPQWQVVLFIFLLVTYMLSVTGNLIIITLTLSDPHLQTPMYFFLRNFSFLEISFTSVCIPRFLVTVVTGNRTISYNGCVAQLFFFIFLGVTEFYLLAAMSYDRCMAICKPLHYTIIMSTRVCTLLVFSSWLAGFLIIFPPVMLLLQLDFCASNVIDHFICDSSPMLQLSCTNTHFLELMAFFLAVVTLMVTLTLVILSYTNIIRTILKIPSMSQRKKAFSTCSSHMIVVSISYSSCIFMYIKTSARERVTLSKGVAVLNTSVAPLLNPFIYTLRNKQVKQAFKSMVQKMIFSLNK
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 6C75.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RNH2_ALTMD
Sequence: MHKLIAGVDEVGRGPLVGDVVTAAVILDPQNPIEGLTDSKKLSEKKRVALAQEIREKALYWNIGRASPEEIDKLNILHATMLAMIRAVEGLPVKPDFVRVDGNRLPAWNFDSEAVVKGDSLHAEISAASIIAKVERDNDMISLHEAFPQYNFAGHKGYPTKAHFEAIAEYGILDCYRKSFKPVKALLEEK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INSF_ECO11
Sequence: MKYVFIEKHQAEFSIKAMCRVLRVARSGWYTWCQRRTRISTRQQFRQHCDSVVLAAFTRSKQRYGAPRLTDELRAQGYPFNVKTVAASLRRQGLRAKASRKFSPVSYRAHGLPVSENLLEQDFYASGPNQKWAGDITYLRTDEGWLYLAVVIDLWSRAVIGWSMSPRMTAQLACDALQMALWRRKRPRNVIVHTDRGGQYCSADYQAQLKRHNLRGSMSAKGCCYDNACVESFFHSLKVECIHGEHFISREIMRATVFNYIECDYNRWRRHSWCGGLSPEQFENKNLA
What is the function of this protein?
Involved in the transposition of the insertion sequence IS3.
What are the official names of this protein?
Transposase InsF for insertion sequence IS3.
What is the protein family that this protein belongs to?
Belongs to the transposase IS3/IS150/IS904 family.
Protein: MKCD_DICDI
Sequence: MNNIKSFFGKKKKTQDQAEPLVIGDDSEKRTVILPPPSPNAVKRKNKNEKPYSIDLNGVGEVGGKVYNNVVGVFADGNDTGEISPTIYCVSDFQGLLKNDRKWIQYSELPEGYTVFYFQTILCVLNFLRRREFVHYIYVDKFEQILEMNENNENIITTVIPTNPIDENDKINSKSINDGDDNGGGSGGGGDNSPLTNVILPTITTTDTTTTSITISPPPKNHLSLLEEDIKNNQNLHHKQQQLQQLQQLKQQHLQQQQKLKQEQQQEQQQQQEDEPNKSPVSTSSTLSPQLESTNFEMTNDDTSLNAPNAMLTPNNISGISYSIIYPGKKKRIDFSRIFVSPGHSFRFPEEYDKALEKHLNEGNPKEHFKNLDFEARGGFGSVFCAKNKNPHSAYDKQMVALKKMPIKTLRHKRMNLSEIGFLKYFNHPNIVKFLCAYQKSNDELWMIMEFLSGGTLKNAASNFKFCERKIAYVCREILQGLDYLHKQNIAHRDLKSANVMVNDKGEIKLIDFGLCIDFSIEKEEINMLGSPSYISPEMINGNPHSLSTDIWSFGICALEMLLGKLPYHDSRLKAMVFVATNNLNLPLLLSTTTSSLEFRDFLTNCLQFDPSKRLTSSQLLQHPFLTKACPIKDFKEILPALYMSNTLSNMF
What are the official names of this protein?
Probable serine/threonine-protein kinase mkcD, MAP kinase cascade D.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
Protein: PTOV1_HUMAN
Sequence: MVRPRRAPYRSGAGGPLGGRGRPPRPLVVRAVRSRSWPASPRGPQPPRIRARSAPPMEGARVFGALGPIGPSSPGLTLGGLAVSEHRLSNKLLAWSGVLEWQEKRRPYSDSTAKLKRTLPCQAYVNQGENLETDQWPQKLIMQLIPQQLLTTLGPLFRNSQLAQFHFTNRDCDSLKGLCRIMGNGFAGCMLFPHISPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVSAIRQVITTRKQAVGPGGVNSGPVQIVNNKFLAWSGVMEWQEPRPEPNSRSKRWLPSHVYVNQGEILRTEQWPRKLYMQLIPQQLLTTLVPLFRNSRLVQFHFTKDLETLKSLCRIMDNGFAGCVHFSYKASCEIRVLMLLYSSEKKIFIGLIPHDQGNFVNGIRRVIANQQQVLQRNLEQEQQQRGMGG
What is the function of this protein?
May activate transcription.  Required for nuclear translocation of FLOT1.  Promotes cell proliferation.
What are the official names of this protein?
Prostate tumor-overexpressed gene 1 protein, PTOV-1, Activator interaction domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 25 family. PTOV1 subfamily.
Protein: RPOE_STRU0
Sequence: MKLDIFAGQEKSELSMIEVARAILEERGRDNEVYFSDLVNDIQTFLGKSDADIRQALPFFYTDLNTDGSFIPLGDNKWGLRSWYAIDEIDEEIITLEDEEDGAPKRKKKRVNAFMDGDEDAIDYSDDDPEDEDFTEETSDVEYDEEDPDDEKSEVESYDSELNEIIPEDDIEEVEINEEDDEDDEEEE
What is the function of this protein?
Participates in both the initiation and recycling phases of transcription.  In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
What are the official names of this protein?
Probable DNA-directed RNA polymerase subunit delta, RNAP delta factor.
What is the protein family that this protein belongs to?
Belongs to the RpoE family.
Protein: SSRP_BURM9
Sequence: MSIIDNRKAFFDYHIEERYEAGLVLEGWEVKALRAGRGQIKEGYVVVKHAEIFLIGTHISPLPEASTHIKPDPVRTRKLLLHRDEIKKLIGKVEQRGYTLVPLNFHYKGGRVKCEIGLAKGKKLHDKRETEKKRDWEREKARIMRSAT
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: GLUQ_RALSO
Sequence: MSQANLEFPESVAAAPRGPYRGRFAPSPTGPLHIGSLVTALASWLDARVHGGTWLVRIEDIDFQRNVPGADRDILASLETLGLVPDEAPQWQSAHLPRFEAALAQLQAIDRLYPCGCTRREIADSITTVDAQGRLRHQTLIYPGTCRNGLMGRPPRAWRVRLPDADAATVCFDDRWQGTQCQNLAEAVGDFVLKRADGMWAYQIAVVVDDAAQGITDVVRGADLLDSTPRQIYLQRLLGLPAVRYLHVPVVVNAAGEKLSKQTGARAINRSQPLAALTEAARHLGLEIRAADMEGFYRAAVPAWAHRLAQLTPAA
What is the function of this protein?
Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp).  Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.
What are the official names of this protein?
Glutamyl-Q tRNA(Asp) synthetase, Glu-Q-RSs.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
Protein: CRTO_STAAB
Sequence: MKTMKKYIKTAFFCSMYWLIVQLNIANLGTRIPDKYFRQKHIIFKSFNFEKHGKFWNKWFYVRKWKHKILDGHQLNRNIYDQRHLMTINSDEIEKMIIETKRAELIHWISILPVIIFNKGPRLVKYINIFYAMIANVPIIIVQRYNRPRLTQLLRILKRRGERHD
What is the function of this protein?
Catalyzes the acylation of glycosyl-4,4'-diaponeurosporenoate, i. e.  the esterification of glucose at the C6'' position with the carboxyl group of the C(15) fatty acid 12-methyltetradecanoic acid, to yield staphyloxanthin.  This is the last step in the biosynthesis of this orange pigment, present in most staphylococci strains (By similarity).
What are the official names of this protein?
Glycosyl-4,4'-diaponeurosporenoate acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the acyltransferase CrtO family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RPOZ_ECOUT
Sequence: MARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPEENDKTTVIALREIEEGLINNQILDVRERQEQQEQEAAELQAVTAIAEGRR
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: DMP1_ARATH
Sequence: MSETSLLIPKTNSPASSENMANTNKSLTGLESLIKLLPTGTLFIYLLLNPVLTNDGECSTGNKVMSSILVALCSFSCVFSCFTDSFKGVDGSRKFGIVTKKGLWTYAEPGSVDLSKYKLRIADFVHAGFVLAVFGTLVLLDANTASCFYPRFRETQKTLVMALPPAVGVASATIFALFPSKRSGIGYAPIAEEVGAEEETKKASVSA
What is the function of this protein?
Involved in membrane remodeling including fission during breakdown of the endoplasmic reticulum (ER) and the tonoplast during leaf senescence and in membrane fusion during vacuole biogenesis in roots.
What are the official names of this protein?
Protein DMP1, AtDMP1.
What is the protein family that this protein belongs to?
Belongs to the plant DMP1 protein family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Vacuole membrane; Multi-pass membrane protein.
Protein: THIE_CLOAB
Sequence: MKNVDYKLYLVTDRKVLKERDLYKSIEEAIKGGVTLVQLREKEMSTLDFYESALKLKKITETYKIPLIINDRIDIALAINADGVHIGQSDMPLIKARELLGKDKIIGVSAHSIEEALEAERNGATYLGVGAIYNTSTKGDAQAVSLEELKNIKNSVKIPVVGIGGINEENANKVIETGVDGISVISGILSAQKIKDKARVMFDIVKKNSTK
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: PSBA_PICAB
Sequence: MTAIIERRESANLWGRFCDWITSTENRLYIGWFGVLMIPTLLTATSVFIIAFIAAPPVDIDGIREPVSGSLLYGNNIISGAIIPTSAAIGLHFYPIWEAASVDEWLYNGGPYELIVLHFLLGVACYMGREWELSFRLGMRPWIAVAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENQSANAGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVAGIWFTALGISTMALNLNGFNFNQSVVDSQGRVINTWADIINRANLGMEVMHERNAHNFPLDLAAVESISIGG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PME7_ARATH
Sequence: MESPIFILITLSFFLQSVLASSQTLSNSSTICKTTPDPKYCKSVFPHSQGNVQQYGCFSIRKSLSQSRKFIRTVDRYIKRNAHLSQPAVIRALQDCRFLAGLTMDYLLTSFETVNDTSAKTSFKPLSFPKADDIQTLLSAALTNEQTCLEGLTTAASYSATWTVRTGVALPLVNDTKLLGVSLALFTKGWVPKKKKRAGFAWAQPRSGSSTHTKPFRLFRNGALPLKMTEKTKAVYESLSRRKLADGDSNGDGDDGSMVLISDIVTVSQDGTGNFTNITAAVAAAPNNTDGSAGFFLIYVTAGIYEEYISIAKNKRYMMMIGDGINQTVVTGNRSVVDGWTTFNSATFAVTAPNFVAVNITFRNTAGPEKHQAVALRSGADFSIFYSCSFEAYQDTLYTHSLRQFYRECDVYGTVDFIFGNAAVVFQNCNLYPRKPMPNQFNAITAQGRSDPNQNTGTSIQNCTIKPADDLVSSNYTVKTYLGRPWKEYSRTVYMQSYIDGFVEPVGWREWNGDFALSTLYYAEYNNTGPGSNTTNRVTWPGYHVINSTDAANFTVTGLFIEADWIWKTGVPYTSGLIS
What is the function of this protein?
Acts in the modification of cell walls via demethylesterification of cell wall pectin.
What are the official names of this protein?
Probable pectinesterase/pectinesterase inhibitor 7.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the pectinesterase family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: FDHD_XANAC
Sequence: MTSPSSRSVRPGSVVRTVRRHRGGRSATVQDMVAAEMPVAFIYNGVPFAVMMATPEDLEDFALGFSLSEGIVDHAQDLRVIAVETFLEGASLQIEIPPERAAALHQRRRNLDGRSGCGVCGNESIEAVLRVPPVLQSSLQIDVDALAHALDALHARQPIAAQTGAVHAAGWADAQGNVQLVREDVGRHNALDKVIGALARARIDASHGFAVVTSRASFEMAMKAAQARIPLLAAISAPTALAISLAESAGLTLIGFARDHDCVVYSHPQRLDLGVAVGEPA
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity.  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
What are the official names of this protein?
Sulfur carrier protein FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF1_HAEIE
Sequence: MAKEDCIEMQGTILETLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVTVEMTPYDLSKGRIIFRSR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPB_PSEP1
Sequence: MRRIAVMGAAGRMGKTLIEAVQQTSGAGLTAAIDRPDSSLVGADAGELAALGRIGVLLSDDLAKVADEFDVLIDFTHPSVTLKNLAFCRKHGKAMIIGTTGFTVEEKQLLAEAGKDIPIVFAANFSVGVNLSLKLLDMAARVLGDDVDIEIIEAHHRHKVDAPSGTALRMGEVVANALGRDLQEVAVYGREGQTGARDRKTIGFATVRAGDVVGDHTVLFAAEGERLEITHKASSRMTFAKGAVRAALWLDGREPGLYDMQDVLELR
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACDG2_METTE
Sequence: MKINSPLEAYKYLPQTNCGECGEATCMAFASKLIDRSGKPTQCPPLVKEKKFAKKLAELERLLAPEIREITIGVGDRAVKIGGDDVLYRHKLTFFNKTKMFYDVTDTMDEAALLERTKKVADFRKFYVGRNLLLDGVAIRSVSNDPEKFAAAVKKVSEVGIPMILCSFNPAVLKAGLEVAKDKNPLIYAANKDNWKEVGELALEYNVPVVVSAFNDLDGLKTLAKTFAEAGIKDIVLDPGTYPSGQGLKDSFTNFLKIRRAGIMGDTEIAYPIMALPITAWMAGISDPVSAAYWETAMAAIFTIRYGDIMILHSLEPYATLPEVHLAETIYTDPRTPVAVDSKMYKVGEPDENSPVLFTTNFALTYYTVESDLSSNGITCWLLAVDTDGIGVEAAAAGGQLTADKVKDAFEKSGFDLKKDVTHNTVIIPGLAARLQGDLEDKLGARVLVGPMDSGRLPGWFEKNWPPK
What is the function of this protein?
Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy.
What are the official names of this protein?
Acetyl-CoA decarbonylase/synthase complex subunit gamma 2, ACDS complex subunit gamma 2, 5-methyltetrahydrosarcinapterin:corrinoid/iron-sulfur protein Co-methyltransferase 2, ACDS complex methyltransferase 2, Corrinoid/iron-sulfur component large subunit 2.
Protein: DADIS_PANGI
Sequence: MWKQKGAQGNDPYLYSTNNFVGRQYWEFQPDAGTPEEREEVEKARKDYVNNKKLHGIHPCSDMLMRRQLIKESGIDLLSIPPLRLDENEQVNYDAVTTAVKKALRLNRAIQAHDGHWPAENAGSLLYTPPLIIALYISGTIDTILTKQHKKELIRFVYNHQNEDGGWGSYIEGHSTMIGSVLSYVMLRLLGEGLAESDDGNGAVERGRKWILDHGGAAGIPSWGKTYLAVLGVYEWEGCNPLPPEFWLFPSSFPFHPAKMWIYCRCTYMPMSYLYGKRYHGPITDLVLSLRQEIYNIPYEQIKWNQQRHNCCKEDLYYPHTLVQDLVWDGLHYFSEPFLKRWPFNKLRKRGLKRVVELMRYGATETRFITTGNGEKALQIMSWWAEDPNGDEFKHHLARIPDFLWIAEDGMTVQSFGSQLWDCILATQAIIATNMVEEYGDSLKKAHFFIKESQIKENPRGDFLKMCRQFTKGAWTFSDQDHGCVVSDCTAEALKCLLLLSQMPQDIVGEKPEVERLYEAVNVLLYLQSRVSGGFAVWEPPVPKPYLEMLNPSEIFADIVVEREHIECTASVIKGLMAFKCLHPGHRQKEIEDSVAKAIRYLERNQMPDGSWYGFWGICFLYGTFFTLSGFASAGRTYDNSEAVRKGVKFFLSTQNEEGGWGESLESCPSEKFTPLKGNRTNLVQTSWAMLGLMFGGQAERDPTPLHRAAKLLINAQMDNGDFPQQEITGVYCKNSMLHYAEYRNIFPLWALGEYRKRVWLPKHQQLKI
What is the function of this protein?
Component of the dammarane-type triterpene saponins (e. g.  ginsenosides or panaxosides) biosynthetic pathway (PubMed:17088293, PubMed:23484102, PubMed:25981048, PubMed:27746309, PubMed:29378087).  Oxydosqualene cyclase that produces specifically the 20S isomer of the triterpene dammarenediol II (PubMed:17088293, PubMed:23484102, PubMed:25981048).
What are the official names of this protein?
Dammarenediol II synthase, Dammarenediol synthase, PgDDS.
What is the protein family that this protein belongs to?
Belongs to the terpene cyclase/mutase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: LPQH_MYCAV
Sequence: MNRQLRFAVAGPEILAAVVSGCSSGNKSAPSSSASSSSTSPSASSGGAAGTKVIIDGKDQNVSGSVVCTNAGGTVNIAIGGAATGIAAVLSDGNPPQVKSVGLGNVNGVTLGYTSGTGQGNASAEKNGNSYKITGTATGVDMANPLQPVNKPFEIDVTCNS
What is the function of this protein?
Might be involved in ligand transport.  A host TLR2 agonist, modifies host gene expression in response to pathogen.
What are the official names of this protein?
Lipoprotein LpqH, 19 kDa lipoprotein antigen, Putative transporter LpqH.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial 19 kDa antigen family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: RF3_STRPN
Sequence: MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVKGKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMAVDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILGIASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDDIELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLETFLKFAPEPHGHKKTDGEIVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNVTQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVSAKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAEVVMNPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDVELEEKM
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX1_BOVIN
Sequence: MFINRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGTLLGDDQIYNVVVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMSQYQTPLFVWSVMITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMMWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFSGYTLNDTWAKIHFAIMFVGVNMTFFPQHFLGLSGMPRRYSDYPDAYTMWNTISSMGSFISLTAVMLMVFIIWEAFASKREVLTVDLTTTNLEWLNGCPPPYHTFEEPTYVNLK
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.