PharMolix/UniProtQA huggingface dataset:
Protein: TRMD_CLOBB
Sequence: MKISILTLFPEMFSIFNHSIIGRAQENNIVELELLNIRDNTLDKHKKVDDYPYGGGAGMVMAPQPIIDTIRKAKENNKGKVIFLGPRGKTFNQKMAMDLSKEENLIFLCGHYEGIDERVYKHIDMEVSLGDFILTGGEMAAIPVIDSILRLIPGVLGKEESFVDESFSEDLLEYPQYTRPYEFEGEHVPEILLSGHHENIRKWRRLQSLDLTRKRRPDLYKNVILTKEDKKLLGRKNK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUT_TROW8
Sequence: MTVEVLFKGGYTPQRAFDGDAGFDLQSSHTAVIQPRCRQVVKTGIAIALPDGYAGFIMPRSGLASENGITLVNSPGVIDAGYRGEISVVLINTDLHQAFHISQGDRIAQLVIMPVCHASFIEVDTLPGSARGISAFGSSGRHDTRG
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: GRPE_ACIBT
Sequence: MANEQNEQAQDIQNEQVEQSNEQTQAEGVEQANDVTVESLQAQITKLEENLKLEKARTANAVYEAQKSVERIQRESEKHKETVLEKFAKELLDSVDNLERAIQAAGDEETPVLEGVKLTLKSLLTTLEKFGVVEADTQNGFNADLHQAVGIDPNAKANEIGTVLQKGYTLNGRLLRPAMVMVGQ
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXC_SALAR
Sequence: MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDLNPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIPIMDGSAAPFVYLLLDAGIDELNCAKKFVRIKETVRVEDGDKWAEFRPYNGFTLDFTIDFNHPAIDSSSQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVVDDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVLANQEAWEFVTFQDDAELPLAFKAPSTVLA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: ACPS_AQUAE
Sequence: MIGVDIVKNERIKDALERFGDKFLDRIYTKRELEYCYAHCDFLPCLAARWAGKEAVLKAFYTEFKIFLRFKEIEILGNRGRPPTVVINREGVEEILKNYEVIVSLSHERDYSVAVAYIKKKS
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_MALP2
Sequence: MSLNQKKKACIFPGTFEVFHDGHLNILKRALKLFDFVYIVVAINNTKTSSDLEKRYQKVEEKIDSLSIKNVEVIKWDSKISDFAKIKTIYFIIRGIRDVNDFKFEKYIADIYKQEWDKLEVVYFFSEKKLENISSRKIINLNKGKNDYEN
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FRS7_ARATH
Sequence: MVVKTYPLGMVGTNNGIAENEGDSGLEPYVGLEFDTAEEARDYYNSYATRTGFKVRTGQLYRSRTDGTVSSRRFVCSKEGFQLNSRTGCPAFIRVQRRDTGKWVLDQIQKEHNHDLGGHIEEAQTTPRPSVQQRAPAPTKLGISVPHRPKMKVVDEADKGRSCPSGVISFKRFKGAEDSDGQTQPKATEPYAGLEFNSANEACQFYQAYAEVVGFRVRIGQLFRSKVDGSITSRRFVCSKEGFQHPSRMGCGAYMRIKRQDSGGWIVDRLNKDHNHDLEPGKKNAGMKKITDDVTGGLDSVDLIELNDLSNHISSTRENTIGKEWYPVLLDYFQSKQAEDMGFFYAIELDSNGSCMSIFWADSRSRFACSQFGDAVVFDTSYRKGDYSVPFATFIGFNHHRQPVLLGGALVADESKEAFSWLFQTWLRAMSGRRPRSMVADQDLPIQQAVAQVFPGTHHRFSAWQIRSKERENLRSFPNEFKYEYEKCLYQSQTTVEFDTMWSSLVNKYGLRDNMWLREIYEKREKWVPAYLRASFFGGIHVDGTFDPFYGTSLNSLTSLREFISRYEQGLEQRREEERKEDFNSYNLQPFLQTKEPVEEQCRRLYTLTIFRIFQSELAQSYNYLGLKTYEEGAISRFLVRKCGNENEKHAVTFSASNLNASCSCQMFEYEGLLCRHILKVFNLLDIRELPSRYILHRWTKNAEFGFVRDVESGVTSQDLKALMIWSLREAASKYIEFGTSSLEKYKLAYEIMREGGKKLCWQR
What is the function of this protein?
Putative transcription activator involved in regulating light control of development.
What are the official names of this protein?
Protein FAR1-RELATED SEQUENCE 7.
What is the protein family that this protein belongs to?
Belongs to the FHY3/FAR1 family.
What are the subcellular locations of this protein?
Nucleus. Note=The nuclear localization is independent of the light treatment.
Protein: DPO3B_STAAM
Sequence: MMEFTIKRDYFITQLNDTLKAISPRTTLPILTGIKIDAKEHEVILTGSDSEISIEITIPKTVDGEDIVNISETGSVVLPGRFFVDIIKKLPGKDVKLSTNEQFQTLITSGHSEFNLSGLDPDQYPLLPQVSRDDAIQLSVKVLKNVIAQTNFAVSTSETRPVLTGVNWLIQENELICTATDSHRLAVRKLQLEDVSENKNVIIPGKALAELNKIMSDNEEDIDIFFASNQVLFKVGNVNFISRLLEGHYPDTTRLFPENYEIKLSIDNGEFYHAIDRASLLAREGGNNVIKLSTGDDVVELSSTSPEIGTVKEEVDANDVEGGSLKISFNSKYMMDALKAIDNDEVEVEFFGTMKPFILKPKGDDSVTQLILPIRTY
What is the function of this protein?
Confers DNA tethering and processivity to DNA polymerases and other proteins.  Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA.  Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity.  The beta chain is required for initiation of replication as well as for processivity of DNA replication.
What are the official names of this protein?
Beta sliding clamp, Beta clamp, Sliding clamp, Beta-clamp processivity factor, DNA polymerase III beta sliding clamp subunit, DNA polymerase III subunit beta.
What is the protein family that this protein belongs to?
Belongs to the beta sliding clamp family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU4LC_PANGI
Sequence: MMLEHVLVLSAYLFSVGLYGLITSRNMVRALMCLELILNAVNINFVTFSDFFDSRQLKGAIFSIFVIAIAAAEAAIGLAIVSSIYRNRKSIRINQSNLLNK
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic, NAD(P)H dehydrogenase subunit 4L, NADH-plastoquinone oxidoreductase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: MINE_SHEB9
Sequence: MSLLDYFKSKKKPSTAVMAKERLQIIVAHQRGQRDTPDYFPQMKQEIIAVIRKYVQISDDQVSVQLDQNDANLSVLELNVTLPDR
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: NU6C_LACSA
Sequence: MDLPGLIHDFLLVFLGLGLILGGLGVVLLPNPIYSAFSLGLVFVCISLFYILSNSHFVAAAQLLIYVGAINVLIIFAVMFINGSEYSKDFHLWTVGDGITSVVCTSLFVSLITTIPDTSWYGIIWTTKANQIIEQDLISNSQQIGIHLSTDFFLPFEFISIILLVALIGAIAVARQ
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 6, chloroplastic, NAD(P)H dehydrogenase subunit 6, NADH-plastoquinone oxidoreductase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: METN2_SALPA
Sequence: MIEIEKVCVDFTAGRGTPTRAVDNVSLHIAAGEIFGIVGTSGAGKSTLLRTLNALTRPSQGRVNVNGVEISALDGKALRQARQRIGMIFQHFNLMHTRTVAQNVAFSLKAAGWERSKIAPRVAEILTLVGLADKANRFPVQLSGGQKQRVGIARAIANHPDVLLCDEPTSALDLETSATILALLRQINAQLGITIVLITHEMNVIKSICDRVAVMSGGKVVESGEVFDVFAHPQHAFTQQLVSHTLNLTLPERLREHLPGQLLKILFIGDSAEQPVLSEVAIKFGVAVNILHGKIEYIGERALGILVVQLTAPHNPTAVAAAVEHIRQRTAQVEVIRG
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LYS2_ECOLX
Sequence: MKKITGIILLLLAVIILSACQANYIRDVQGGTVSPSSTAEVTGLATQ
What is the function of this protein?
Lysis proteins are required for both colicin release and partial cell lysis.
What are the official names of this protein?
Lysis protein for colicins E2 and E3.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: WBP2L_HUMAN
Sequence: MAVNQSHTENRRGALIPNGESLLKRSPNVELSFPQRSEGSNVFSGRKTGTLFLTSYRVIFITSCSISDPMLSFMMPFDLMTNLTVEQPVFAANFIKGTIQAAPYGGWEGQATFKLVFRNGDAIEFAQLMVKAASAAARGFPLRTLNDWFSSMGIYVITGEGNMCTPQMPCSVIVYGAPPAGYGAPPPGYGAPPAGYGAQPVGNEGPPVGYRASPVRYGAPPLGYGAPPAGYGAPPLGYGAPPLGYGTPPLGYGAPPLGYGAPPAGNEGPPAGYRASPAGSGARPQESTAAQAPENEASLPSASSSQVHS
What is the function of this protein?
May play a role in meiotic resumption and pronuclear formation, mediated by a WW domain-signaling pathway during fertilization.
What are the official names of this protein?
Postacrosomal sheath WW domain-binding protein, WW domain-binding protein 2-like.
Protein: ISF1_YEAS8
Sequence: MIASEIFERGVQDPFCQDCDYEDETDVQSFLGSNDLNDFVNSKLASFSFQNSSKSNNSHHSSSTNAGNTSRHIGNHTIGHHLRKIKTAPHHLYGFVPANSTNNSNEPIRPSPRRIRANSSTLIHQLSRQSTRQSSLGDAADSCFDHKCIKPRSRHSSCYGIPTHLYGLEKYVSSELDSLAVANDQSNDLTSPLTSVSTPASNSNSYLNLNSSSAAYPSSYLSNEKNNRLKLISHGKISSNNVPGHSGNLNHYHRERTPSNLRRESFSLLSNGSSSSPLQTRNNSYSNSLVKSPSNSSLNTSVASSNEESIPHTSNCLEERNPRRKSFIKLSLASSFSN
What is the function of this protein?
Could influence the NAM7/UPF1 function, possibly at the level of mRNA turnover.  Participates in mitochondrial biogenesis (By similarity).
What are the official names of this protein?
Increasing suppression factor 1, Mitochondrial biogenesis regulation protein 3.
What is the protein family that this protein belongs to?
Belongs to the ISF1/MBR1 family.
Protein: Y5266_AFIC5
Sequence: MLGWVVTFLIIALVAGLLGFGGIAGASIEIAKIVFFIAIVLFAVSAVVGLMRGRRPMV
What are the official names of this protein?
UPF0391 membrane protein OCAR_5266/OCA5_c27040.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y2274_STAAN
Sequence: MMHSKKLMLGICLVLLIILIVGYVIMTKINSRSAQIKDTFNQTLKLYPTKNLEDFYDKEGFRDQEFEKGDKGNWIVDSEMVIELKDKKMESRSMVLYINRNTRTTKGNFIVRELWEDSKGYAQSKDTKYPVKMEHNRIIPTKPIADDKLRKEIENFKFFVQYGDFKDINDYKDGDISYNPNVPSYSAKYQLKNDDYNVKQLRKRYNIPTNKAPKLLLKGDGDLKGSSIGSKNLEFTFVENKEENIYFSDSINFKPTE
What are the official names of this protein?
Uncharacterized protein SA2274.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal tandem lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: GLPK_MYCLE
Sequence: MAEFAEFIAAIDQGTTSTRCVIFDHNGAEVARHQLEHEQILPRSGWVEHNPVEIWERTASVLMSVLNATNLSAKDIAALGITNQRETTLVWNRNTGRPYCNAIVWQDTRTDRIAVALDRDGRGEVIRRKAGLPPATYFSGGKLQWILENVDGVGAAAENGEALFGTPDTWLLWNLTGGPRGGVHVTDVTNASRTMLMDLEKLDWDDELLSFFSIPRAMLPAIASSSPLQPYGVTLADGPVGGEVPITGVLGDQHAAMVGQVCLDAGEAKNTYGTGNFLLLNTGEAIVRSGNGLLTTVCYQFGDAKPVYALEGSIAVTGSAVQWLRDQLGIISGAAQSESLARQVVDNGGVYFVPAFSGLFSPYWRSDARGAIVGLSRFNTNAHLARATLEAICYQSRDVVDAMAADSGVRLDVLKVDGGITSNDLCMQIQADVLGVDVVRSVVAETTALGSAYAAGLAVGFWAGPSDLRANWQEDKRWTPTWGEDQRAAAYAGWRKAVQRTLDWVDVS
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: AGL8_SINAL
Sequence: MGRGRVQLKRIENKINRQVTFSKRRSGLLKKAHEISVLCDAEVALVIFSSKGKLFEYSTDSCMEKILERYDRYLYSDKQLVGRDISQSENWVLEHAKLKARVEVLEKNKRNFMGEDLDSLSLKELQSLEHQLHAAIKSIRSRKNQAMFESISALQKKDKVLQDHNNALLKKIKEREKNTVHQEVQLIQCSNNSSILQPQYCLTSSRDGFVGRVEGENEGASSLAEPNSLLPAWMLRPTTNE
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
Agamous-like MADS-box protein AGL8 homolog, MADS B.
What are the subcellular locations of this protein?
Nucleus.
Protein: EIF3E_DROMO
Sequence: MAQFDLTRINCQYLDRHLTFPLLEFLCGKEIYNQQELLEYILETVNKTNMIDYTMDTRKRLNLSQEMPEELVQRKAEVLATLKQLQNEVAPIMKATDILKNGESMKDSKTFVNALQKDYNFKVEHLESAYKLAKYLYECGNYQESTSYLYFCLIVMSPNDKNYLNVLWGKLAAEILTLNWNTALEDLTRLRDYIDSANFSTIQALQQRTWLIHWSVLVFFNHPKGRDLIIEMFLYKPLYLNAIQTMCPHIMRYLATAVVINRTRRNALKDLIKVIQQESYTYRDPITEFLECLYVNFDFEGARLKLHECQTVILNDFFIVACLNEFVEDARLMIFETFCRIHQCITISMLADKLNMKPNEAECWIVNLIRNARLNAKIDSKLGHVVMGTQPLSPYQQLVEKIDSLSMRSEHLAGLIERKSKQKNQESIDSWKYY
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit E, eIF3e, Eukaryotic translation initiation factor 3 subunit 6.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit E family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBPYA_TALSN
Sequence: MRVLSTTLLIGAAAAAVSPPQQVLQAPEEAVENTHKSSPSLAESLSQPLRELKEELKLLTNEVEEVWEEVSNIFPGALDNIFFSSAKKHTRRPDSHWDHIIRGSDVQNIWVENENGEKEREVGGRLEAFDLRVKAVDPSSLGIDPDVKQYSGYLDDNENDKHLFYWFFESRNDPKTDPVVLWLNGGPGCSSLTGLFFELGPSSIGKNIKPIYNPYSWNSNTSVIFLDQPVNVGFSYSGNSVSETSAAAKDVYALLTLFFKQFPEYSSQDFHIAGESYAGHYIPSFASEILSHKKRNINLKSVLIGNGLTDGLTQYEYYRPMACGDGGYPAVLDETTCRSMDNALGRCQSMIQSCYDSESAWTCVPASIYCNNALLGPYQRTGQNVYDVRKPCEDSSLCYADLEYVSTYLNQAEVMKALGAEVDSFDSCNFDINRNFLFKGDWMKPFHKLVPGLLEEIPVLIYAGDADFICNWLGNKAWTDALEWAGHEEYAATELEDLEIVDNKHKGKKIGQVKSSGNLTFMRLFGGGHMVPYDQPEASLEFFNRWIGGEWTK
What is the function of this protein?
Vacuolar carboxypeptidase involved in degradation of small peptides.  Digests preferentially peptides containing an aliphatic or hydrophobic residue in P1' position, as well as methionine, leucine or phenylalanine in P1 position of ester substrate (By similarity).
What are the official names of this protein?
Carboxypeptidase Y homolog A.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Vacuole.
Protein: ATR5_STAC4
Sequence: MAVMTREDVEFRTMDGLTLRGWLYPSGMRGPALVMTQGFNASKEYLLADVAVWFQKRGVTSLLVDIRTTGLSDGEPRNDIDLDKQVEDCHDAVSFLSRHPSVDPEMIVYWGYSLGAVISLCAAALDKRAAAVIATAPNTDFIFDPVKRAATLSLAMRDRLSRLAGNPPLYLKIIGEDGQNPAGWYLGEERRSPEELDALFNSSNIMNQVTIQSYYRLLRWQPFGLMPSVSPTPVMIVTPSDDDLSKPENQRKLFDIFQEPKEFVLAENKGHMNCISGEDGEQFLQKQLEFMKRMLKF
What is the function of this protein?
Polyketide transferase; part of the core atranone cluster (CAC) which products are predicted to catalyze most or all steps of atranone synthesis, starting from geranylgeranyl pyrophosphate (GGPP) (PubMed:25015739).  The initial cyclization of GGPP to dolabellane is probably performed by the terpene cyclase ATR13 (PubMed:25015739).  The Baeyer-Villiger oxidation near the end of the atranone synthesis, which converts atranones D and E to atranones F and G is predicted to be catalyzed by the monooxygenase ATR8 (PubMed:25015739).  Of the CAC's other predicted gene products, the reducing PKS ATR6 might synthesize a polyketide chain (PubMed:25015739).  This polyketide is probably transferred onto the atranone backbone by the polyketide transferase ATR5 (By similarity).  Other predicted CAC products include 4 oxygenases (ATR2, ATR3, ATR4, and ATR14), 3 short-chain reductases (ATR7, ATR9, and ATR10), and a methyltransferase (ATR12) (PubMed:25015739).  These may all be involved in the various steps of atranone biosynthesis, although their specific roles must await experimental determination (PubMed:25015739).
What are the official names of this protein?
Polyketide transferase ATR5, Core atranone cluster (CAC) protein 5.
What is the protein family that this protein belongs to?
Belongs to the polyketide transferase af380 family.
Protein: SYG_MALP2
Sequence: MSKKIDQETIVNHFKNYGFVYQNSEIYNGLANAWDFGPLGSLIKNNLKNLWLKHFIYSKKEMHLIDTNIILNPLVWKASGHIDNFSDPLIDCKECKSRFRADKLILENTKEEINEQTDSDTLIKIISDNKIKCPNCKKSNWTEIRKFNLMFDTSIGVVDDKKDLVYLRPETAQGIFINFKNIQRTQRQKLPFGVGQIGKAFRNEITPGNFIFRTREFEQMEIEYFCDKKDSPKVFDNFLESIKTFLFKTLKIHENNIKIIDYPKEELAHYSSRTVDFLYNFPHGYSELWGLADRGEFDLTAHQNLSKKSLEYLNEETKEKFVPSVIEPSVGVERLLYAILIDAYDEEKIDEENNRVVLKLIPELAPYKFAVLPLSNKLNDKAEEIFNNLILSNICTYDSSGSIGKRYRRQDAIGTPYCITVDFDTLEDECVTIRDRDSMKQIRIKIKDIDLSKVQELFKNAK
What is the function of this protein?
Catalyzes the attachment of glycine to tRNA(Gly).
What are the official names of this protein?
Glycine--tRNA ligase, Glycyl-tRNA synthetase, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NGRN_MOUSE
Sequence: MALSLSLFLGGRVRTSLARCGFASQVMAGPGSVSCEPDPDSDWEPEERELQEVESALKRQKKAMRFQKIRRQMEAPGAPPRTLTWEAMEQIRYLHKEFAESWSVPRLAEGFDVSTDVIRRVLKSKFVPTLEQKLRQDQKVLKKAGFTREIGQLPVSEDTLKALSAGRSVSGLLMAGDEVSSKSQNHSTALKVAKSHPHSTDAQKKREGRDKRIQVLEESLVPATTALGHQRELQKSATSDSEATGRAGSDTLPSAVLLEELKPGEPGDQSFSSKVVQRGHDFFDSNGNFLYRI
What is the function of this protein?
Plays an essential role in mitochondrial ribosome biogenesis.  As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.
What are the official names of this protein?
Neugrin, FI58Gm, Neurite outgrowth-associated protein, m-Neugrin.
What is the protein family that this protein belongs to?
Belongs to the neugrin family.
What are the subcellular locations of this protein?
Nucleus. Secreted. Mitochondrion membrane.
Protein: ILVD_SHEAM
Sequence: MAKLRSATSTEGRNMAGARALWRATGVKDTDFGKPIIAIANSFTQFVPGHVHLKDMGSLVASAIEEAGGIAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADALVCISNCDKITPGMLMAALRLNIPVVFVSGGPMEAGKTKLSDKLIKLDLVDAMVAAADDRISDADSEKIERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSMLATHADRRELFLEAGRRVMKLAKRYYGDDDASVLPRSIASFKAFENAMALDVAMGGSSNTVLHLLAAAQEAEVDFTMDDIDRISRKVPHLCKVAPSTPKYHMEDVHRAGGVMAILGELDRAGLLHTDVNHVASEDGTLKSVLERFDVVLTKDEKVHEFFRAGPAGIPTTRAFSQSCRWDTLDDDRREGCIRSREFAFSQEGGLAVLSGNLAENGCIVKTAGVDESNLKFSGVARVYESQEDAVAGILGGEVVAGDVVVIRFEGPKGGPGMQEMLYPTSYLKSRGLGTQCALITDGRFSGGTSGLSIGHVSPEAASGGTIGLIENGDRIDIDIPGRSIKLLVSDAELESRRAAMNAKGPLAWKPLSRVRPVSMALKAYAMLATSADKGAVRDVSKLEG
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: GPMI_THEVB
Sequence: MASSPVAPVVLVILDGWGYREETYGNAIASAYTPVIDSLWQAYPHTLIHTSGKAVGLPKGQMGNSEVGHLNIGAGRIVPQELVRISDAVEEGSLFSNPVLVRLCQTVKERNGKLHFIGLCSAGGVHSHIDHLYGLVELAKRHGLPACIHVITDGRDTPPRDAAGVLEELEQRLKTSGCGRIVTVSGRYYAMDRDRRWERTEAAYRVMTSNEHIQPLRAVDVARQSYAQDIGDEFIVPTRIAAGAVEPGDGVVFFNFRPDRARQLTQAFIDPNFSGFERALITPLDFVTFTQYDASFNCGVAFPPQNLSHILGEVIAEHGLKQLRAAETEKYAHVTYFFNGGLEEPFPGEDRILIPSPMVTTYDQAPAMSALAVTQAVKKAIEKQEYALVVVNFANSDMVGHTGKLAATIQAIETVDRCVGVLVEAATKVGGTLLITADHGNAEYMIDEDGNPWTAHTTNPVPFILVEGEKRKVPGHGGHVILRKDGCLADIAPTILEILELPQPLEMTGRSLIVSAPYEMRLNRTPVSLKI
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: TRMFO_GEOSM
Sequence: MTQQITVIGGGLAGCEAAWQAAKRGVKVRLFEMKPNCYSEAHHLPGLSELVCSNSLRGDSLENAVGLLKEELRRLESLFMEGAEATKVPAGGALAVDRDLFSQYITSRIESHPLIEVVREEVTRIPEEGIVVLASGPLTAGLLAQEIGRLAGSYLYFYDAIAPIVAADSIDYGKAFRASRYGKGDGDDYVNCPMDEEQYQAFVREILAAEKVEPKSFEKVVHFEGCMPIEEMASRGPETLRFGPMKPVGLVDPRVGVEPHAVIQLRQENLEATMYNLVGFQTKLTWPEQKRIFRMIPGLENAQFLRLGSMHRNTFINAPELLMATCQLKSDQRIFFAGQITGVEGYVESASSGFAVGVNAARLSKGEGLVVPPAETAIGALARHITNTEAAHFQPMNVNYGLFPPLPGRIKKKEKRGLLAQRGLEALEMWLPELS
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.