PharMolix/UniProtQA huggingface dataset:
Protein: SOPE_SALDU
Sequence: MTKITLFPHNFRIQKQEATPLKEKSTEKNSLAKSILAVKNHFIKLNSKLSERFISHKNTESSATHFHRGSASEGRAVLTNKVVKNFMLQTLHDIDIRGSASKDPAYASQTREAILSAVYSKYKDQYCNLLISKGIDIAPFLKEIGEAAQNAGLPGATKNDVFSPSGAGANPFITPLITSAYSKYPHMFTSQHQKASFNIYAEKIIMTEVVPLFNECAMPTPQQFQQILENIANKYIQNTP
What is the function of this protein?
Acts in concert with other proteins to mediate cellular responses leading to bacterial internalization.  Activator for both CDC42 and RAC1 by directly engaging these Rho GTPases and acting as potent guanine nucleotide exchange factor (GEF).  This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling, promoting bacterial entry into non-phagocytic cells (By similarity).
What are the official names of this protein?
Guanine nucleotide exchange factor SopE, Effector protein SopE, Toxin SopE.
What is the protein family that this protein belongs to?
Belongs to the GEF (guanine exchange factor) SopE family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the type III secretion system 1 (SPI-1 TTSS).
Protein: SYL_LAWIP
Sequence: MIMHSNYDPNIIEKKWQRYWEEQHAYACDIDPNKKKYYVLEMWPYPSGNIHMGHVRNYSIGDVIARIKRMQGYNVLHPMGWDAFGLPAELAAIKHHTQPADWTYTNINEMRAQLKRLGYSYDWQREIATCDPDYYQWEQLFFVDCFEKGLVYRKKAPQNWCPSCNTVLANEQVIEGSCWRCDTSIIQKELTQWFLKITDYAEELLDDLTTLKYSWPDRVITMQENWLGKSTGVEISFPIESSQDFITIFTTRPDTIFGATAIILAPEHPILETLLNDTPQKEKLYNVIEKMRNMDRLERQSNLLTKEGIFIDRYCINPCSGDKIPIWIGNFVLADYGTGAIMAVPAHDQRDFDFCKKYNLPISIVIQPDELQINEHTIVEPWTGLGTLIHSGQFTGLTNKEAKEKITQYLEKIGKATRVVSWRLRDWNISRQRYWGTPIPIIYCKNCGVVSVPKNELPVILPTNITINEDGSSPLPQESSFIDCMCPQCGGIAKRETDTMDTFVDSSWYFARFVDPKNTKQPFDTSIAKYWLNVDQYIGGVEHAILHLLYSRFFTKLLRDLGYLPSNINEPFAKLLTQGMVIKDGSKMSKSKGNIVDPNQMINIYGADTIRLFCLFAAPPERDFDWSDSGIEGSYRFLHRVWRLFIDVQPHIHTTHAGNSTVIETTTALTKDVKRKEHITIKKVSEDIENKYQFNTAIASIMEFVNTLYLSKNELILTVEGKNILSSAIATVLTLLSPMTPHICEELWSYLGHSTSISLEPWPKWDPQALLKDVVTIVVQINGKVRNKFEVPMDLSKEELEHIIFNDTKITQYLEGKTIQKHIIIPNKIINIVTT
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_TETTS
Sequence: MDKSVRVFKLRTQTEEQLVGELGKLQTELSQLRIAKIAGGTANKLGRIGIVRKAIAKYLTIINEKRRQAVKDQFKGKSLKPLDIRVKKTRAIRRKLTKKQREAVLVKTQKKLNNFGLRKFALKA
What are the official names of this protein?
60S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: HQDA_ASPNC
Sequence: MDPSKVKIPPMKDLTVDNITENVIRINSLCQDERLKYVLERLVTHLHDFARETRLSTDEWMTGLRFLTEVGKICSDVRQEYILLSDILGLSILVDSIDHPKPPNSTEGTVLGPFHTHDAEPLTPGASISHDPAGEPLLVVCTVKDTHGNPVSDVKIDIWETDSTGHYDVQYAGRDGPDGRCIMTSDKEGVFWFKAITPVPYPIPHDGPVGKLLKLLGRHPYRPSHMHFMFEKGGFDHLITALYLRNDPYETSDAVFGVKDSLVVDIGKAGPEYAAKYGVSEDHALLTYDFVLVSDEETSELRARNSKEALDKLGRKVKIVNGLPVPDLD
What is the function of this protein?
Intradiol ring-cleavage dioxygenase involved in an alternative pathway to the protocatechuic acid pathway since it is active on hydroxyquinol and catechol but not on protocatechuic acid.
What are the official names of this protein?
Intradiol ring-cleavage dioxygenase hqdA.
What is the protein family that this protein belongs to?
Belongs to the intradiol ring-cleavage dioxygenase family.
Protein: HIS5_SALTY
Sequence: MNVVILDTGCANLSSVKSAVARHGYTPVVSREAEIVLRADKLFLPGVGTAQAAMDQLRERELIDLIKACTQPVLGICLGMQLLGRRSEETRGVDLLNIIEQDVPKMTDFGLPLPHMGWNRVYPQAGNRLFQGIEDGAYFYFVHSYAMPVNPWTIAQCNYGEPFTAAVQKDNFFGVQFHPERSGAAGAQLLKNFLEM
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTND_SCLS1
Sequence: MRAYWFDNKEGDQRELHDSGRDVDPEYLEKLGVLYYHFADEKDVDKLASDRSYKNRDVITVSPQKMGDVYEEKVKMFFNEHLHEDEEIRYIRDGAGFFDVRSEGDEWVRIRLEKDDLIILPAGIYHRFTTDDKNYIQAMRLFKEEPKWTPLNRGPEVDANPYRKEYLQTVPAIASQ
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: LOX3_PEA
Sequence: MFSGVTGILNRGHKIKGTVVLMRKNVLDINSLTTVGGVIGQGFDILGSTVDNLTAFLGRSVSLQLISATKPDATGKGKLGKATFLEGIISSLPTLGAGQSAFKIHFEWDDDMGIPGAFYIKNFMQTEFFLVSLTLDDIPNHGSIYFVCNSWIYNAKHHKIDRIFFANQTYLPSETPAPLVHYREEELNNLRGDGTGERKEWERIYDYDVYNDLGNPDSGENHARPVLGGSETYPYPRRGRTGRKPTRKDPNSESRSDYVYLPRDEAFGHLKSSDFLTYGLKAVSQNVVPALESVFFDLNFTPNEFDSFDEVHGLYEGGIKLPTNILSQISPLPVLKEIFRTDGENTLKYPPPKVIQVSRSGWMTDEEFAREMLAGVNPNVICCLQEFPPRSKLDSQIYGDHTSKISKEHLEPNLEGLTVEEAIQNKKLFLLDHHDSIMPYLRRINSTSTKAYATRTILFLNNNQNLKPLAIELSLPHPQGDEHGAVSYVYQPALEGVESSIWLLAKAYVIVNDSCYHQLVSHWLNTHAVVEPFVIATNRHLSCLHPIYKLLYPHYRDTMNINSLARLSLVNDGGIIEKTFLWGRYSMEMSSKVYKNWVFTEQALPADLIKRGMAIEDPSSPCGVKLVVEDYPYAVDGLEIWAIIKTWVQDYVSLYYTSDEKLRQDSELQAWWKELVEVGHGDKKNEPWWPKMQTREDLIEVCSIVIWTASALHAAVNFGQYSYGGLILNRPTLSRRFMPEKGSAEFEELVKSPQKAYLKTITPKFQTLIDLSVIEILSRHASDELYLGERDNPNWTSDKRALEAFKKFGNKLAEIEKKLTQRNNDEKLRNRHGPVEMPYTLLYPSSKEGLTFRGIPNSISI
What is the function of this protein?
Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.  It catalyzes the hydroperoxidation of lipids containing a cis,cis-1,4-pentadiene structure.
What are the official names of this protein?
Seed linoleate 9S-lipoxygenase-3, Lipoxygenase-3.
What is the protein family that this protein belongs to?
Belongs to the lipoxygenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX51A_SCODE
Sequence: MKEAVKMSCLCIFVFLFLFSLTDAIKCIKCGESGLFGTEDCVTGTFEAEECGPNDQYCTKIILNDGTRTTAQRGCSVGHVPESNQKDGKVSTHMSSCNTDGCNAN
What are the official names of this protein?
U-scoloptoxin(05)-Ssd1a, U-SLPTX(05)-Ssd1a, Toxin SSD202.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-05 family.
What are the subcellular locations of this protein?
Secreted.
Protein: GP1_SOLLC
Sequence: MHTKIHLPPCILLLLLFSLPSFNVVVGGDGESGNPFTPKGYLIRYWKKQISNDLPKPWFLLNKASPLNAAQYATYTKLVADQNALTTQLHTFCSSANLMCAPDLSPSLEKHSGDIHFATYSDKNFTNYGTNEPGIGVNTFKNYSEGENIPVNSFRRYGRGSPRDNKFDNYASDGNVIDQSFNSYSTSTAGGSGKFTNYAANANDPNLHFTSYSDQGTGGVQKFTIYSQEANAGDQYFKSYGKNGNGANGEFVSYGNDTNVIGSTFTNYGQTANGGDQKFTSYGFNGNVPENHFTNYGAGGNGPSETFNSYRDQSNVGDDTFTTYVKDANGGEANFTNYGQSFNEGTDVFTTYGKGGNDPHINFKTYGVNNTFKDYVKDTATFSNYHNKTSQVLASLMEVNGGKKVNNRWVEPGKFFREKMLKSGTIMPMPDIKDKMPKRSFLPRVIASKLPFSTSKIAELKKIFHAGDESQVEKMIGDALSECERAPSAGETKRCVNSAEDMIDFATSVLGRNVVVRTTEDTKGSNGNIMIGSVKGINGGKVTKSVSCHQTLYPYLLYYCHSVPKVRVYEADILDPNSKVKINHGVAICHVDTSSWGPSHGAFVALGSGPGKIEVCHWIFENDMTWAIAD
What is the function of this protein?
Non-catalytic subunit of the polygalacturonase isozyme 1 (PG1).  Necessary and sufficient to convert the polygalacturonase from its monomeric form PG2 to its heterodimeric form PG1.  Seems to limit the depolymerization and solubilization of cell wall polyuronides mediated by PG2 during ripening, probably by recruiting PG2 to form PG1.
What are the official names of this protein?
Polygalacturonase-1 non-catalytic subunit beta, AroGP1, Polygalacturonase converter, PG converter.
Protein: AROC_STRPZ
Sequence: MRYLTAGESHGPSLTAIIEGIPAGLTLHPADIDHELQRRQGGYGRGARMSIETDRVQISSGVRHGKTTGAPITLTVINKDHQKWLDVMAVGDIEETLKLKRRVKHPRPGHADLVGGIKYHFNDLRDALERSSARETTMRVAVGAVAKRILAELGIDMLHHILIFGGITITIPSKLSFRELQERALHSELSIVNPKQEEEIKTYIDKIKKEGDTIGGIIETIVQGVPAGLGSYVQWDKKLDAKLAQAVLSINAFKGVEFGVGFDMGFQKGSQVMDEITWTPTQGYGRQTNHLGGFEGGMTTGQPIVVKGVMKPIPTLYKPLMSVDIDSHEPYKATVERSDPTALPAAGVIMENVVATVLAKEILETFSSTTMSELQKAFSDYRAYVKQF
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: FTSL_NEIG1
Sequence: MNKSNFFLLLAVCVSAFSVVMQQNQYRLNFTALDKAKKQEIALEQDYAQMRLQQARLANHEAIRAAAEKQNLHPPVSGNTFMVEHQR
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsL.
What is the protein family that this protein belongs to?
Belongs to the FtsL family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum where it forms a ring structure.
Protein: SYD_XYLFT
Sequence: MRTHFCGLINETLIGHTVTLAGWTDVARNLGGVCFIDLRDHEGIVQITVDSRAIDQNNSELFRVASGLSYEDVLQVEGVVHARHAVNDKIKTGKVEVIATKIKILNKAAPLPFHAHENPGEDIRLKYRYLDLRRPEMQRMQRTRIKLVQALRRHLDMHGFQDIETPILTKATPEGARDFLVPARMHPGEFYALPQSPQLFKQILMVAGFDRYYQIARCFRDEALRADRQLEFTQLDMEFAFVSERDVQDFVEEMIRRVFKEVAGIELDTTFPRMTWKEAMRRFGSDKPDMRINLELIDVAALVADSTFTPFTNAVAHPNGRVAALRIPRGAVLSRKQIDEYAAYTAKYGATGLAYAKLAPTGEITSPIAKFFSEDAFAALLSHIGAEKGDIVFFGAGNYNKVSDFMGALRLKAGKDFALITADWRPLWVTDFPMFEWDEEAQRYVALHHPFTAPAAINDIDELRTHARTALSRGYDMVLNGNEIGGGSIRIHRPEMQRAVFELLGITEDEARAKFGFLLDALNYGAPPHGGIAFGIDRIAALIAGTESIRDVIPFPKTTGAQCLMTDAPSPISEEQLSEIHVITKKLTP
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPA_MYCLE
Sequence: MLSACNRMRRSSEFDATVKFGLRAVQSDVIIHVWRGCNRDETKAPHVGLIIAKTVGSAVERHRVARRLRHVARTMLGELGGADQVVIRALPSSRNVSSAWLAQQLRNGLRCALDLAETDW
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: GCH1_CLOPS
Sequence: MIDKDKIREGMKLILEAIGEDANREGLIETPDRIARMYEEIFSGIGMNAKEHLSKTFEVHSNDLVLEKDITFYSMCEHHLVPFYGKVHIAYIPNGRVVGLSKLARCVEVYSKKPQLQERLTTEIADSIMEYLDAQGVMVVVEGEHMCMTMRGVRKPGAKTVTTTYRGKFLEDESLKNDVFRMISM
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: METK_XANCB
Sequence: MSSYLFTSESVSEGHPDKIADQISDAVLDAILAQDKRARVACETMVKTGVAIVAGEVTTSAWIDLEALTRKVILDIGYNSSDVGFDGETCGVLNLIGKQSPDINQGVDRKNPEQQGAGDQGLMFGYATNETDSYMPAAIHLSHRLVEQQAKIRKKKNSALSWLRPDAKSQVTLRYEDGVATAIDAVVLSTQHDPGVKQKDLIEAVREEILKPVLPAKWLHKGTKFHINPTGKFVIGGPVGDCGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAARYVAKNVVAAGLADRCEVQVSYAIGVAEPTSISVTTFGTGKIADELIEKLIRKHFDLRPFGIIQMLDLIHPMYQQTASYGHFGRKPKDFTYTDGTGAQHSATSFSWEKTDRAEALRAAAKLK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPH_CLOBH
Sequence: MSYNLTDPYEIARYIKEAKKSTPIKAYIEGDLSNCDFTNIEKFNSGDLYILFGESEEILVIIEKNKDKIKNCRIEQDRRKSAIPLLDMLKINARIEPGATIRDKVIIGENAVIMMGAVVNIGAEIGEGTMVDMNAVVGARGKLGKNVHLGAGAVVAGVLEPPSSDPCTIEDNVLIGANAVILEGVKIGKGSVVAAGSIVTTDVPENVVVAGAPAKIIKEVDVKTKDKTKLLDDLRK
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. DapH subfamily.
Protein: PURA1_PHYPA
Sequence: MAMAAAAAVASQGLVAASTQQQKKTSAKLSCNAAPVFSGKSFLRVKSGSNGAVRVRNVGVRCEAQAIERESVKADTGSGREEDAFSGLKQVCAVLGTQWGDEGKGKLVDILAQRFDVVARCQGGANAGHTIYNDKGEKFALHLVPSGILNEKTTCVVGNGVVIHLPGFFKEIDNLESKGVNTSGRLLVSDRAHLLFNLHQEVDGLREAELAGQMIGTTKRGIGPCYASKAIRNGIRVGDLRHLDTFREKLDILFRDAAARFKGFEYSAAAVDAEMEMYVKYAERLEHYIVDTVDYVNTAYAEGKRILIEGGQATMLDIDFGTYPFVTSSNPSVGGICTGLGMAPNRLGDIVGVAKAYTTRVGSGPYPTELFGEEGEELRKAGFEWGTTTGRPRRCGWLDIVALNFACTINGFTAINLTKLDVLSGLPEVKLGVAYRTQSGEKLRSFPADLSILEQVEVEYETLEAWKEDITKVRSYAELPVAAQKYVERIEELIGLPCQYIGVGPGRDALIVKQ
What is the function of this protein?
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
What are the official names of this protein?
Adenylosuccinate synthetase 1, chloroplastic, AMPSase 1, AdSS 1, IMP--aspartate ligase 1.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GREA_STAA2
Sequence: MENQKQYPMTQEGFEKLERELEELKTVKRPEVVEKIKVARSFGDLSENSEYDAAKDEQGFIEQDIQRIEHMLRNALIIEDTGDNNVVKIGKTVTFVELPGDEEESYQIVGSAESDAFNGKISNESPMAKALIGKGLDDEVRVPLPNGGEMNVKIVNIQ
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: QUEA_PECCP
Sequence: MRVADFSFELPESLIAHYPQAERSGCRLLSLDGPTGDLTHGVFTDLLDKLNPGDLLVFNNTRVIPARLFGRKVSGGKLEVLVERVLDDHRVLAHVRASKAPKPGTELLLGDDESVKATMAARHDALFELHFDDSRDVLSILNDIGHMPLPPYIDRPDEDADRELYQTVYSQRPGAVAAPTAGLHFDEPMLAALREKGIEMAFVTLHVGAGTFQPVRVDTIEDHIMHAEYAEVPQDVVDAVLACKARGNRVIAVGTTSVRSLESAAQASQNAPIEPFFGDTKIFIYPGYHYRIIDALVTNFHLPESTLIMLVSAFAGYQNTMSAYRQAVAEQYRFFSYGDAMFITHNPMAEQEKVG
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR7_MARSD
Sequence: MSKHVVETDIKELKLLSRGKVRDIYEVDDDKLLLVTTDRISAYDVIMPNPIDDKGKILNQITLFWMDMFKDIIPNHLIASKVDDYPEVLHKYRDQLEGRSVLVKKAKPLPIECIVRGYITGSGWKDYQKTGEVCGHKLPEGLKESEMLEQPLFTPSTKAELGEHDENISVEKATEMLGKELFDKVQEATLSIYKRGRDYAREKGIIIADTKFEFGIYDGELIIIDEVLTPDSSRFWPVEGYEAGKSQPSFDKQFLRDWLTEINFNKQPPAPEVPEEIATKTRDKYMEAFTLLTESELDA
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: HIS2_BURP6
Sequence: MTQSTTEDTLLRLAAVIDSRKGGDPEQSYVSRLFHKGDDAILKKIGEEATEVVLAAKDVRQGGAPSALVGEVADLWFHCLVALSHFDLSPADVIAELERREGMSGIEEKALRKRREREENGG
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAN1_RAT
Sequence: MAEELITPVYCTGVSAQVQKQRDKELGLGRHENAIKYLGQDYENLRARCLQNGVLFQDDAFPPVSHSLGFKELGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDCWLLAAIASLTLNETILHRVVPYGQSFQEGYAGIFHFQLWQFGEWVDVVVDDLLPTKDGKLVFVHSAQGNEFWSALLEKAYAKVNGSYEALSGGCTSEAFEDFTGGVTEWYDLQKAPSDLYQIILKALERGSLLGCSINISDIRDLEAITFKNLVRGHAYSVTDAKQVTYQGQRVNLIRMRNPWGEVEWKGPWSDNSYEWNKVDPYEREQLRVKMEDGEFWMSFRDFIREFTKLEICNLTPDALKSRTLRNWNTTFYEGTWRRGSTAGGCRNYPATFWVNPQFKIRLEEVDDADDYDSRESGCSFLLALMQKHRRRERRFGRDMETIGFAVYQVPRELAGQPVHLKRDFFLANASRAQSEHFINLREVSNRIRLPPGEYIVVPSTFEPNKEGDFLLRFFSEKKAGTQELDDQIQANLPDEKVLSEEEIDDNFKTLFSKLAGDDMEISVKELQTILNRIISKHKDLRTNGFSLESCRSMVNLMDRDGNGKLGLVEFNILWNRIRNYLTIFRKFDLDKSGSMSAYEMRMAIEAAGFKLNKKLHELIITRYSEPDLAVDFDNFVCCLVRLETMFRFFKILDTDLDGVVTFDLFKWLQLTMFA
What is the function of this protein?
Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.  Proteolytically cleaves CTBP1 at 'Asn-364', 'Gly-377' and 'His-399'.  Cleaves and activates caspase-7 (CASP7).
What are the official names of this protein?
Calpain-1 catalytic subunit, Calcium-activated neutral proteinase 1, CANP 1, Calpain mu-type, Calpain-1 large subunit, Micromolar-calpain, muCANP.
What is the protein family that this protein belongs to?
Belongs to the peptidase C2 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=Translocates to the plasma membrane upon Ca(2+) binding.
Protein: NUOH_BDEBA
Sequence: MGMGKDIFEITVNGLKLVVIFLMMVQAVPILVWLERRGSAFIQDRLGPNRVGPLGLVQLLADAVKFLNKENFMPQTAKPFLYYAAPIFALIPGAVAFSAIPLSSPIQVGTFEMFGSTWGPYTFLVQGYDIGVGIVFILGVSSLAAYTLLMAGWGSGNKYTLMGALRASAQTISYELALGLSIVGVIMLYGTFNLTEMTLAQQGPLAFSFLGHTITANWLPNWGIFYQPVGALLFFSAAFAESNRLPFDLAEGESELVGGFHTEYGGFKFNMFFIGEYGHMMIASGLMVLFFFGGYTIPYVSVAELNEWAAGVASTAGKASALVALIHFLVFNIKFGFFMWVFIWVRWTLPRFRYDQLMDLGWKTMLPWALANTIITAFVIYIASL
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KDSB_MYXXD
Sequence: MQSCRTVAVIPARHASTRFPGKPLAIIAGRTMIEHVWRRCQEAQAFDEVWVATDDDRIRAAVEGFGGKAVMTSPACATGTDRVAEVALGRPDIDIWVNVQGDEPLVDPATLQRLAGLFQDASVRMGTLVRPLEADEAASPHVVKAVLALNGDALYFSRSLVPHVREPGTPVQRWGHIGLYGYRREVLLSLAKLAPTPLEDAEKLEQLRALEHGIPIRCAKVTSHTVAVDLPGDVEKVEALMRARGG
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDGD_CORGL
Sequence: MARFSPQDLADHLKDGLLSFPATAFQDDLEVDEAAYVEHIEWQSSYPVAGLFAAGGTGEGFSLTVEENHRVTQLAVQASSPEVPVLGSATGSTKSAIANAQGAEAAGAEGVLLLPPYLTECDAEGLYNHAAAVCESTSLGVIVYNRANAIYSPEVIARLSERYPNFIGFKDGTGNIEHLAKITTLCGDRLFYLGGLPTAETFALPLLQMGMSTYSSAMFNFIPDFALSFYADVRAQDSAAVKQKLSDFVLPYLDIRDRAQGYGVSIVKGGLKAVGRNAGGVRPPLRNLSEQDIADLSDLLATSGAGSYRLPVEVKA
What are the official names of this protein?
Probable 5-dehydro-4-deoxyglucarate dehydratase, 5-keto-4-deoxy-glucarate dehydratase, KDGDH.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
Protein: M1_I01A2
Sequence: MSLLTEVETYVLSIIPSGPLKAEIAQRLEDVFAGKNTDLEALMEWLKTRPILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALNGNGDPNNMDRAVKLYKKLKREITFHGAKEVALSYSTGALASCMGLIYNRMGTVTTEGAFGLVCATCEQIADSQHRSHRQMATTTNPLIRHENRMVLASTTAKAMEQMAGSSEQAAEAMEVANQARQMVQAMRTIGTHPNSSAGLRDNLLENLQAYQKRMGVQMQRFK
What is the function of this protein?
Determines the virion's shape: spherical or filamentous.  Clinical isolates of influenza are characterized by the presence of significant proportion of filamentous virions, whereas after multiple passage on eggs or cell culture, virions have only spherical morphology.  Filamentous virions are thought to be important to infect neighboring cells, and spherical virions more suited to spread through aerosol between hosts organisms.
What are the official names of this protein?
Matrix protein 1, M1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses Matrix protein M1 family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Cytoplasmic side. Host nucleus.
Protein: GPDA_METPP
Sequence: MRITVLGAGAWGTALSVGIAPRHDTLLWARDAAQAAHIEASRDNRRYLPGVALPAALRLTADLDAAIAHAQADGGLIVIATPMSGLREMLARCAASGAGLWWLCKGFEAGTGALGHEVAREVAPAARVGVLSGPSFALEVARGQPTALVAASTDEALRNQAVEAFHSESLRVYTSADPVGVEVGGAVKNVIAIATGIADGMGLGLNARAALVTRGLAEITRLGTALGARVDTFMGLSGLGDLVLTATGDLSRNRQVGLQLAQGRSLPEVLAALGHVAEGVYSAATVLARAQALGVDMPITAAVVAVLDGRLTPAQALERLMRRQARAEGHAPD
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.