PharMolix/UniProtQA huggingface dataset:
Protein: MQO_PECAS
Sequence: MKKLLAMFFCLSVVVSAPLAMAEDAKTTEKTTDVVLIGGGIMSSTLGVYLQELQPDWSIDMVERMDNVAEESSNGWNNAGTGHSAFMELNYTPDNPDGPINISKALEITEAFEISRQFWSYQVKNGVLNNPHAFINSVPHISFVWGDENTAFLKHRYDAMQHSTLYRGMEFSDDPNTIKEWVPLVMEGRDPAQKIAATRMPIGTDVNYGEITRQLVSAMKTKSNFALHLNSEVRDIKRNADNTWSVTYADLKNGEKESVIKAKFVFIGAGGAALKLLQKSGIPEADLYGGFPVGGEFLVTENPEIVKRHMAKVYGKASVGAPPMSVPHLDTRIFDGKPVLLFGPFATFSSKFLKNGSLWDLIGSVTFSNVMPMTHVGLDNFDLVKYLVSQVMMDDDDRFASLQEYFPNAKKEDWRLTVAGQRVQVIKKDDDKGGVLKLGTEIVSSQDGSIAALLGASPGASTAAPIMLSLLEKVFKDKVATPEWQSKLKEIVPSYGQKLDGNIEMTNKIRSYTSSTLGLDYIEVKPE
What are the official names of this protein?
Probable malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: 5054R_ASFK5
Sequence: MFSLQDICRKHLFLLPSSFNEYILQVLGLYWEKHGSLQRIRKDAVFVQRNITLSTNEALRIAASEGNERVVKLLLSWEGNFHYVIIGALEGDQYDLIHKYNSQIKDYHVILSSIQNANTFEKCHQLYNCTMWRLVQNAIKYNMLSILQKHRNLLTDEGDNQELFEKACEEQKYDIVLWIGQTLMLDEPKSIFDIALERIDFSLLIMGYSLLFANKMSSIDIHDEEDLTSLLTEHLEKAATKGCLFFMQETLKHGGNVNIAVLSKAVEYNHRKILDYFIRRQKCLSRKDIEKLLLIAIKDGGSKKTLNLLLSYLNYSVQNMIGKIVEAVINDGDFTIIIILKKKKINLVDSVLAGFLDHFHTYCFIKVFIHEFAIRPEKIIKMAARKDKLDIIIEFFNDIYPHKDDLGTILNILKNIVNTMKHKEGKEVLIGLIHKIYRIIHLENKEMFNLVRFYIMHNANIQFISICKDCFNLAGFKPFLSECLDIAIKKNYPDIVRNIKIQLKYE
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 505-4R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 505 family.
Protein: POXP_PENOX
Sequence: MPVQPCSLPAGFLPAAVSLPSQQTVIAEDETGKATIYHDAPLPIPEPHMVLVKTIAVSINPCDWKMPSRFPAPGARIGCDFAGIVLSIGPEAARIRRDLRIGDRVCGGIHGSNPIDLPSGSFSQYVAAHADLLLKLPNKLSFAQGAVLGGSVFATLWIALYESLGLEGTPDMPLQDDPPPVLVYGGSTSTGTAALQILRLSGYRPIATCSPHNNDLVRAAGAEKVFDYRSETCAADIKSYTNGRLRHVLDIITDLQSQLICYDTFSRVGGKYTCLEQPAEELHLRRTVRKEMIVGLAASGKEIALADGYERTANPQLRARSGEFFQTIQRLVDEGKFVPHPTRTVEGGFEGILKCLDILKSGGTSGEKLVVFVDRENP
What is the function of this protein?
Trans-enoyl reductase; part of the gene cluster that mediates the biosynthesis of oxaleimides, cytotoxic compounds containing an unusual disubstituted succinimide moiety (PubMed:28365998).  The first step of the pathway is provided by the HR-PKS poxF that serves in a new mode of collaborative biosynthesis with the PKS-NRPS poxE, by providing the olefin containing amino acid substrate via the synthesis of an ACP-bound dec-4-enoate (PubMed:28365998).  The cytochrome P450 monooxygenase poxM-catalyzed oxidation at the alpha-position creates the enzyme-bound 2-hydroxydec-4-enoyl-ACP thioester, which may be prone to spontaneous hydrolysis to yield 2-hydroxydec-4-enoic acid due to increased electrophilicity of the carbonyl (PubMed:28365998).  2-hydroxydec-4-enoic acid can then be further oxidized by poxM to yield the alpha-ketoacid 2-oxodec-4-enoicacid, which is reductively aminated by the aminotransferase poxL to yield (S,E)-2-aminodec-4-enoic acid (PubMed:28365998).  The Hybrid PKS-NRPS synthetase poxE then performs condensation between the octaketide product of its PKS modules and the amino group of (S,E)-2-aminodec-4-enoic acid which is activated and incorporated by the adenylation domain (PubMed:28365998).  The resulting aminoacyl product can be cyclized by the Diels-Alderase PoxQ and reductively released by the reductive (R) domain of poxE to yield an aldehyde intermediate (PubMed:28365998) (Probable).  The released aldehyde is then substrate for a Knoevenagel condensation by the hydrolyase poxO followed by an oxidation at the 5-position of the pyrrolidone ring (PubMed:28365998).  The presence of the olefin from the amino acid building block allows for migration of the substituted allyl group to occur (PubMed:28365998).  This allylic transposition reaction takes place in a conjugate addition, semipinacol-like fashion to yield a succinimide intermediate (PubMed:28365998).  Iterative two-electron oxidations of the C7 methyl of the succinimide intermediate to the carboxylic acid can be catalyzed by one of two remaining cytochrome P450 monooxygenasess poxC or poxD to yield oxaleimide A (PubMed:28365998).  Subsequent oxidation yields the maleimide scaffold oxaleimide I (PubMed:28365998).  Both oxaleimide A and oxaleimide I can undergo oxidative modifications in the decalin ring to yield the series of products oxaleimides B to H (PubMed:28365998).
What are the official names of this protein?
Trans-enoyl reductase poxP, Oxaleimides biosynthesis cluster protein P.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: IF3_BUCAT
Sequence: MKGGKRVQLTRPNRINSEIRAIKVRLTGVEGDQIGIVNLREALKKSEELGLDLVEISPNAEPPVCRIMDYGKFLYEKSKSSKEQKKKQKVIHIKEIKFRPGTDEGDYQVKLRNLIRFLEDGDKAKITLRFRGREMAHQKIGVDVLNRVKNDLIELATVEYFPSKIEGRQMIMILAPKKK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CP9_CONAA
Sequence: SCNNSCQQHSQCASHCVCLLNKCRTVN
What is the function of this protein?
Probable neurotoxin that inhibits ion channels.
What are the official names of this protein?
Conotoxin.
What is the protein family that this protein belongs to?
Belongs to the conotoxin P superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TLCOE_ALOMR
Sequence: EDEVEETLPVAEEGREKSCITWRNSCVHNDKGCCFPWSCVCWSQTVSRNSSRKEKKCQCRLW
What is the function of this protein?
Modulates P-type voltage-gated calcium channels (Cav2. 1/CACNA1A) in rat cerebellar Purkinje cells and hippocampal CA1-CA3 neurons.  At saturating concentrations (>10 nM) the toxin decelerates activation kinetics and slightly increases peak amplitude without affecting deactivation kinetics (By similarity).
What are the official names of this protein?
Omega-lycotoxin-Gsp2671e, Omega-LCTX-Gsp2671e, Omega-Lsp-IA-like 6.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin (omega-lctx) family.
What are the subcellular locations of this protein?
Secreted.
Protein: PCX1_TAKRU
Sequence: MGSQTLQILRQGVWASVTGGWYYDPDQNTFVNALHLYIWLFLLCFPFTLYMALQPSMVIVGIYCGVIAAMFLLLKTVNYRLHHALDEGEVVEHQTRESKGSRGGTGGANDPVTRREDSNGLGDPGGGIEMADFIRQETPPVDCSSRNSYVGMDLNQRMSSTHGRTTVAKAPGSEETVIFRRERSTFRRQAVRRRHNAGSNPTPPTSLIGSPLRYALHEADRPSGVRSWYRTVKSQPSRTPSQVTVLSTSASLLARNGSTHLEGSQDKASTVGTTSLQDEFGTLTPSLYEIRGCHIGLGNFESATRRASNNIWDTDSHLSSSTSVRFYPHDLISLHHIRANRLLTMDPELLEQQDDLSPDLQDAPLGQDNPSAASAAGKTRQYYRLWLLPFLWVGLHFDRLTLLALFDRNREVLENVLAVVLAVLVAFLGSVLLIHGFFADIWVFQFCLVIASCQYSLLKSVQPDSSSPRHGHNRIIAYSRPVYFCLCCGLIWLLHYGSLRTTSSRFTLYGVALTSSLVLASARDLVIVFTLCFPIIFFVGLLPQVNTFVMYLFEQLDIHVFGGNASTSLLSALYSILRSIVTVALLYCFCYGALKENWEPHHIPVLFSVFCGLLVAVSYHLSRQSSDPSVLMYVPLSKVFPQLRSKNPEDPLSEVQDPLPEKLRASVNERLQSDLIVCVVIAVLYFAIHVSTVFIALQPYLSYVLYGLLGAVGLLTHYLLPQLRKQLPWYCFSHPLLKTKEYYQFEVRDAAHVMWFEKFHVWLLFVEKNVLYPLVILNELSGSARELASPKRLDTEVGALMITVAGLKLLRSSYSSPTYQYITILFTVLFFTLDHRHLSETLLLDLFLMSIIFSKMWELFYKLHFVYTYIAPWQITWGSAFHAFAQPFAVPHSAMLFVQAVVSSIFSTPLNPFLGSAIFITSYVRPVKFWERDYNTKRVDHSNTRLASQLDRNPGSDDNNLNSIFYEHLTRSLQHSLCGDLLLGRWGNFSTGDCFILASDYLNALVHLIEIGNGLVTFQLRGLEFRGTYCQQREVEAITEGVEEDEGCCCCEPGHLPHILSFNAAFGQRWLAWEVVVTKYVLEGYSITDNSAASMLQVFELRRILTTYYVKGIIYYVIASPKLEEWLANDTMKEGLRGCSERNYVDLDATFNPNIDEDYDHRLSGISRDSFCGVYLGWIQYCNSRRTKPLDSEKDSALVLLCFGLCVLGRRALGTAAHQMSSNLESFLYGLHALFKGDFRISSVRDEWIFADMELLRKVVVPGIRMSLKLHQDHFTSPDEYDEPAVLFEAISTHQQNLVIAHEGDPAWRSAVLSNAPSLLALRHVLDEGTNEYKIIMLNRRYLSFRVIKVNKECVRGLWAGQQQELVFLRNRNPERGSIQNAKQALRNMINSSCDQPIGYPIYVSPLTTSYCNSHPQLRHILGGPISFGNIRNFVVSTWHRLRKGCGAGCNSGGNIEDSDAGGLSCGTSQSSQSVQSGLVRHSPARASVVSQSSSYRYSSSRHSSLRTSTTGLEPCRRSSTSQLSLRTLPTSLQLRLGSTSDPAGPSSSLSSHSIPPCKRHTLVGLLGNDGLCSTVTDPLSQHHHPHHHPQQHNPTHATVRRDDISYRVQIVDVGQVLENINLSKRKELQWPDDAMRHKAGRTCWRDWSPLEGMEGHVIHRWVPCSRDPGSRSHIDKTILLVQVEDKIVPIIETGVIELGAEV
What are the official names of this protein?
Pecanex-like protein 1, Pecanex homolog protein 1.
What is the protein family that this protein belongs to?
Belongs to the pecanex family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ECHA6_MYCTO
Sequence: MIGITQAEAVLTIELQRPERRNALNSQLVEELTQAIRKAGDGSARAIVLTGQGTAFCAGADLSGDAFAADYPDRLIELHKAMDASPMPVVGAINGPAIGAGLQLAMQCDLRVVAPDAFFQFPTSKYGLALDNWSIRRLSSLVGHGRARAMLLSAEKLTAEIALHTGMANRIGTLADAQAWAAEIARLAPLAIQHAKRVLNDDGAIEEAWPAHKELFDKAWGSQDVIEAQVARMEKRPPKFQGA
What is the function of this protein?
Could possibly oxidize fatty acids using specific components.
What are the official names of this protein?
Probable enoyl-CoA hydratase echA6.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
Protein: CU92A_CONCL
Sequence: MNCYLILTVALLLTSAMTGTTTAGQLNKKGVTLREDDGFPCNAGNCACLPLDSYSYTCQSPTSSTANCEGNECVSEADW
What is the function of this protein?
Probable neurotoxin with unknown target.  Possibly targets ion channels.
What are the official names of this protein?
Conotoxin Cal9.2a.
What are the subcellular locations of this protein?
Secreted.
Protein: NRDR_CHLAB
Sequence: MQCPFCNHGELKVIDSRNAPEANAIKRRRECLNCGQRFTTFETVELTLQVLKRDGRYENFQESKLINGLNAASSHTRIGQDQVHAIASNVKSELLGKQNREISTKEIGELVMKYLKKADMIAYIRFACVYRRFKDVGELMEVLLSATPDMEK
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: LEPA_ECO57
Sequence: MKNIRNFSIIAHIDHGKSTLSDRIIQICGGLSDREMEAQVLDSMDLERERGITIKAQSVTLDYKASDGETYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAGQGVEAQTLANCYTAMEMDLEVVPVLNKIDLPAADPERVAEEIEDIVGIDATDAVRCSAKTGVGVQDVLERLVRDIPPPEGDPEGPLQALIIDSWFDNYLGVVSLIRIKNGTLRKGDKVKVMSTGQTYNADRLGIFTPKQVDRTELKCGEVGWLVCAIKDIHGAPVGDTLTLARNPAEKALPGFKKVKPQVYAGLFPVSSDDYEAFRDALGKLSLNDASLFYEPESSSALGFGFRCGFLGLLHMEIIQERLEREYDLDLITTAPTVVYEVETTSREVIYVDSPSKLPAVNNIYELREPIAECHMLLPQAYLGNVITLCVEKRGVQTNMVYHGNQVALTYEIPMAEVVLDFFDRLKSTSRGYASLDYNFKRFQASDMVRVDVLINGERVDALALITHRDNSQNRGRELVEKMKDLIPRQQFDIAIQAAIGTHIIARSTVKQLRKNVLAKCYGGDISRKKKLLQKQKEGKKRMKQIGNVELPQEAFLAILHVGKDNK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SDR1_ARATH
Sequence: MAEETPRYAVVTGANRGIGFEICRQLASEGIRVVLTSRDENRGLEAVETLKKELEISDQSLLFHQLDVADPASITSLAEFVKTQFGKLDILVNNAGIGGIITDAEALRAGAGKEGFKWDEIITETYELTEECIKINYYGPKRMCEAFIPLLKLSDSPRIVNVSSSMGQLKNVLNEWAKGILSDAENLTEERIDQVINQLLNDFKEGTVKEKNWAKFMSAYVVSKASLNGYTRVLAKKHPEFRVNAVCPGFVKTDMNFKTGVLSVEEGASSPVRLALLPHQETPSGCFFSRKQVSEF
What is the function of this protein?
Aldehyde reductase that catalyzes the reduction of the aldehyde carbonyl groups on saturated and alpha,beta-unsaturated aldehydes with more than 5 carbons (PubMed:21169366).  Involved in basal resistance against pathogens.
What are the official names of this protein?
(+)-neomenthol dehydrogenase, Menthone:neomenthol reductase, Short-chain dehydrogenase/reductase 1, AtSDR1.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXT_STRPN
Sequence: MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSGLILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGTMDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVAAQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: PFD3_BOVIN
Sequence: MAASKDGCGVGEVAAGNGRRLHLGIPEAVFVEDVDSFMKQPGNETADIVLKKLDEQYQKYKFMELNLAQKKRRLKGQIPEIKQTLEILKYKQKKKESTSSLETRFLLADNLYCKASVPPTDKVCLWLGANVMLEYDIDEAQALLEKNLLTATKNLDSLEEDLDFLRDQFTTTEVNMARVYNWDVKRRNKDDSTKNKA
What is the function of this protein?
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it.  Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity).
What are the official names of this protein?
Prefoldin subunit 3, von Hippel-Lindau-binding protein 1, VBP-1, VHL-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit alpha family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=In complex with VHL can translocate to the nucleus.
Protein: HSFC1_ARATH
Sequence: MEDDNSNNNNNNNVIAPFIVKTYQMVNDPSTDWLITWGPAHNSFIVVDPLDFSQRILPAYFKHNNFSSFVRQLNTYGFRKVDPDRWEFANEHFLRGQKHLLNNIARRKHARGMYGQDLEDGEIVREIERLKEEQRELEAEIQRMNRRIEATEKRPEQMMAFLYKVVEDPDLLPRMMLEKERTKQQQQVSDKKKRRVTMSTVKSEEEEVEEDEGRVFRVMSSSTPSPSSTENLYRNHSPDGWIVPMTQGQFGSYETGLVAKSMLSNSTSSTSSSLTSTFSLPESVNGGGGGGCGSIQGERRYKETATFGGVVESNPPTTPPYPFSLFRGGF
What is the function of this protein?
Transcriptional regulator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE).
What are the official names of this protein?
Heat stress transcription factor C-1, AtHsfC1, AtHsf-08.
What is the protein family that this protein belongs to?
Belongs to the HSF family. Class C subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: EZRA_STAA9
Sequence: MVLYIILAIIVIILIAVGVLFYLRSNKRQIIEKAIERKNEIETLPFDQNLAQLSKLNLKGETKTKYDAMKKDNVESTNKYLAPVEEKIHNAEALLDKFSFNASQSEIDDANELMDSYEQSYQQQLEDVNEIIALYKDNDELYDKCKVDYREMKRDVLANRHQFGEAASLLETEIEKFEPRLEQYEVLKADGNYVQAHNHIAALNEQMKQLRSYMEEIPELIRETQKELPGQFQDLKYGCRDLKVEGYDLDHVKVDSTLQSLKTELSFVEPLISRLELEEANDKLANINDKLDDMYDLIEHEVKAKNDVEETKDIITDNLFKAKDMNYTLQTEIEYVRENYYINESDAQSVRQFENEIQSLISVYDDILKEMSKSAVRYSEVQDNLQYLEDHVTVINDKQEKLQNHLIQLREDEAEAEDNLLRVQSKKEEVYRRLLASNLTSVPERFIIMKNEIDHEVRDVNEQFSERPIHVKQLKDKVSKIVIQMNTFEDEANDVLVNAVYAEKLIQYGNRYRKDYSNVDKSLNEAERLFKNNRYKRAIEIAEQALESVEPGVTKHIEEEVIKQ
What is the function of this protein?
Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation.  Inhibits FtsZ ring formation at polar sites.  Interacts either with FtsZ or with one of its binding partners to promote depolymerization.
What are the official names of this protein?
Septation ring formation regulator EzrA.
What is the protein family that this protein belongs to?
Belongs to the EzrA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=Colocalized with FtsZ to the nascent septal site.
Protein: PLB1_CAVPO
Sequence: MGLQPGVLLVGLLLLGQGITQIHTSSGKSTLEGQLWPETKKNFPFSCSPKKLGLNMPSESVHTLTPADIKLIAAIGDMETPPDSGAVNLDTSERTEKEPWRGCMGMMTVLSDIISHFNPSVLLPTCPPWRSAAVRGGVEELRTQAEELVSSLKKNPQLDFQQDWKLINVFFSNASLCYLCPSAHENGPLMSNMDKLAGILHYLHQEVPRAFVNLVDLFEVVAMPRWHQGTMLSRPSPEACGCSGETSKLDTVVMQWSYQETWDSLLASSSFNDQESFAVVFQPFFYEVSSPVEEPPSQDPTTLALSLWNNMMKPVGQKDEPFSTIERRPMKCPSQESPYLFTYRNSNYQSRLLKRQRQHKEREGTEIRCPDKDPSDSTPTSVHRLKPADIKVIGALGDSLTAGNGAGSRPGNILDVLTEYRGLSWSIGADHNISSVTTLPNILREFNPSLKGFSTGTGKANSVGAFFNQAVAGARAGDLIPQARTLVDLMKNHTSINFEEDWKIITVFIGGNDLCDFCSDPVTNSPENFTDNIRQALDILHAEVPRAFVNMVKVLQIVNLRELYKDSRVSCPRLILRNLCRCVLLPDDNSTELESLIDINKKYQERTHQLIESGRYDTREDFTVVLQPFFEKVDIPKTSEGLPDNTSFAPDCFHFSSKTHARAASALWKNMLEPVGQKTTQNNFENSIDIICPNQAFPYLSTYKNGIEGHGTWLTCRERTPSASPPTSVHALRPADVRVVAALGDSLTAGSGIGSKPGDLADVITQYRGLSYSSGGDGSLMNVTTLPNILREFNSNLTGYAVGTGDASNTNAFLNQAVPGAKAEELMSQVKTLVQKMKDDPRINFHEDWKVITVLIGTNDLCNHCTDLDLYSSANFFNHLLNALDILHREVPRALVNLVDFMNPSIMRQVFLGNPDKCPVQQASILCNCVLSLRENSYELARMDALTRAYQSSMRELVESGRYDTREDFSVVLQPFFLNIRLPILEDGRPDTSFFAPDCINPGQKFHSQLSRALWVNMLEPVGSKTDTLDLTADISLPCPTQEEPFLRTPQNSDYTYPTKPAIENWGSDFLCTEWKPSNSVPTSVHKLQPADIKVVAALGDSLTTAVGARASNSSDLLMSWRGLSWSIGGDGALETHTTLPNILKKFNPSIFGFSTGTLEETAGFNVAVEEARARDMPAQARDLVERMKASTEINLEMDWKLITLFIGSNDLCHYCDNPENHSAEEYVQHIRQALDILYEELPRAFINVVDIIMELAGLHQGQGGHCTALLPAQSTCSCLRHFPSSPVIQELKKVTWNLQSDMSRLSYQEKYTQREDFAVVVQPFFQNTLIPLDKLGSTDPTFFSEDCLHFSERGHAEMAIALWNNMLEPVGHKTTFNNFTYNRTKLKCPSTESPYLYTLQNSLSLPVQTEKASGVAPGIVSAAAAGGLLVGLIVGILAVSLWSSFRRRQKKSPPESVPVANF
What is the function of this protein?
Calcium-independent membrane-associated phospholipase that catalyzes complete diacylation of phospholipids by hydrolyzing both sn-1 and sn-2 fatty acyl chains attached to the glycerol backbone (phospholipase B activity) (PubMed:2722844).  Has dual phospholipase and lysophospholipase activities toward diacylphospholipids.  Preferentially cleaves sn-2 ester bonds over sn-1 bonds (PubMed:2722844, PubMed:9593672).  Acts as a lipase toward glycerolipid substrates (By similarity).  Hydrolyzes fatty acyl chains of diacylglycerols with preference for the sn-2 position and of triacylglycerols with not positional selectivity (By similarity).  May also hydrolyze long chain retinyl esters such as retinyl palmitate (By similarity).  May contribute to digestion of dietary phospholipids, glycerolipids and retinoids, facilitating lipid absorption at the brush border (By similarity).
What are the official names of this protein?
Phospholipase B1, membrane-associated, Phospholipase B, Lysophospholipase, Phospholipase A2, Phospholipase B/lipase, PLB/LIP, Triacylglycerol lipase.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family. Phospholipase B1 subfamily.
What are the subcellular locations of this protein?
Apical cell membrane; Single-pass type I membrane protein. Note=Present in the intestinal brush border membranes.
Protein: GHOS_ECOLI
Sequence: MEGKNKFNTYVVSFDYPSSYSSVFLRLRSLMYDMNFSSIVADEYGIPRQLNENSFAITTSLAASEIEDLIRLKCLDLPDIDFDLNIMTVDDYFRQFYK
What is the function of this protein?
Antitoxin component of a type V toxin-antitoxin (TA) system.  Neutralizes the toxic effects of toxin GhoT by digesting ghoT transcripts in a sequence-specific manner (PubMed:22941047).  In concert with GhoT is involved in reducing cell growth during antibacterial stress (PubMed:24373067).  Overexpression leads to transcript level reduction of 20 other mRNAs involved in purine or pyrimidine synthesis and transport.  Not seen to bind its own promoter DNA (PubMed:22941047).
What are the official names of this protein?
Endoribonuclease antitoxin GhoS, Antitoxin GhoS.
Protein: PFDA_SULIL
Sequence: MSQGQGGITLDDLIAQADYLKRYIDSLQRTQLELLESINSIDSAKQAIETIKSGNKEMLVFIDRKGYLLAKVGGIVGDKVTVHLGLSYYAEVDLDSAIKILDKRKDEISKAAQNLNNELQKAASTYNQIVDILNQIQQAAARRQQGE
What is the function of this protein?
Molecular chaperone capable of stabilizing a range of proteins.  Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
What are the official names of this protein?
Prefoldin subunit alpha, GimC subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the prefoldin alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPD_CHRVO
Sequence: MITPQAALNRLIDGNELFYDEMLALMRQIMRGELSPAQTAAILIGLRVKVESVSEIAAAATVMREFATHVPVSDRRHLVDTCGTGGDKSHTFNISTTSAFVAAAAGARVAKHGGRSVSSSSGSADVLELLGVNLQLTPEQVGQCLDEIGLGFMFAPNHHSAMKHVAPIRKELGARTIFNILGPLTNPAAADHQLMGVFHPDLVGIQSRVLKMLGSRHVMIVHGCDGLDELTLSGPSMVAELKNGEILEYELEPGEFGFPLCELKDLRADTAAQSRDRLLAVLDGQPGPARDIVLLNAGAAIYTADIAPSLADGVTMAREALDSGKAKQKLQQLIALSRKLGG
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: NCAP_MAGV
Sequence: MIELEFNDVAANTSSTFDPEIAYVNFKRIHTTGLSYDHIRVLYIKGREIKTSLTKRSEWEVTLNLGGWKVAVFNTNFPGNRNSPVPDDGLTLHRLSGFLARYLLEKILKVSDPEKLIIKSKIINPLAEKNGITWADGEEVYLSFFPGSEMFLGTFKFYPLAIGIYKVQKKEMEPKYLEKTMRQRYMGLEAATWTVSKVNEVQAALTVVSGLGWKKTNVSAAAREFLAKFGINM
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the orthobunyavirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Note=Internal protein of virus particle.
Protein: IHFA_CERS1
Sequence: MSDKTLTRMDLSEAVFREVGLSRNESAQLVESVLQHVSDALASGETVKISSFGTFTVRDKSARIGRNPKTGDEVPISPRRVLTFRPSHLMKERVAAGGKN
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: NU5C_BRADI
Sequence: MEHTYQYAWVIPLLPLPVILSMGFGLFLIPIATKNFRRIWAFPSVLLLSIAMVFSVQLSIQQINGSSIYQYLWSWTINNDFSLEFGYLIDPLTSIMLMLITTVGILVLIYSDGYMSHDEGYLRFFIYISFFNISMLGLVTSSNLIQIYFFWELVGMCSYLLIGFWFTRPIAASACQKAFVTNRIGDFGLLLGILGFFWITGSLEFRDLFQTANNWIPNNGTTSLLTTLCAFLLFLGAVAKSAQFPLHVWLPDAMEGPTPISALIHAATMVAAGIFLLARLLPLFISLPLIMTFISLVGTITLFLGATLALAQRDIKRTLAYSTMSQLGYMMLALGIGSYQAALFHLITHAYSKALLFLGSGSIIHSMEPLVGYSPDKSQNMALMGGLRKYIPITRTAFLWGTLSICGIPPLACFWSKDEILSNSWLYSPFFGIIASFTAGLTAFYMFRIYLLTFDGYFRFHFQNYSSTKEGSLYSISLWGNRIPKGVSKDFVLSTTKSEVYFFSQNISISKGQGNTRNRIESFSTSFGSKNVFTYPHETGNTMLFPLLILLLFTFFIGFIGIPFDNETMDNGIAGVTILSKWLIPSINFTQESSNSSINSYEFITNAISSVSLVILGLFIAYIFYGSAYSFFQNLDLQNSFYKGSPKKNFFYQVKKKIYSWSYNRGYIDIFYSRLFTLGIRGLTELTEFFDKGVIDGITNGVGLASFCIGEEIKYVGGGRISSYLFFFLCYVSVFLFFFLS
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 5, chloroplastic, NAD(P)H dehydrogenase subunit 5, NADH-plastoquinone oxidoreductase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: LPPK_MYCBO
Sequence: MRRNIRVTLGAATIVAALGLSGCSHPEFKRSSPPAPSLPPVTSSPLEAAPITPLPAPEALIDVLSRLADPAVPGTNKVQLIEGATPENAAALDRFTTALRDGSYLPMTFAANDIAWSDNKPSDVMATVVVTTAHPDNREFTFPMEFVSFKGGWQLSRQTAEMLLAMGNSPDSTPSATSPAPAPSPTPPG
What are the official names of this protein?
Putative lipoprotein LppK.
What is the protein family that this protein belongs to?
Belongs to the MTB12 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.