PharMolix/UniProtQA huggingface dataset:
Protein: SIR1_MOUSE
Sequence: MADEVALALQAAGSPSAAAAMEAASQPADEPLRKRPRRDGPGLGRSPGEPSAAVAPAAAGCEAASAAAPAALWREAAGAAASAEREAPATAVAGDGDNGSGLRREPRAADDFDDDEGEEEDEAAAAAAAAAIGYRDNLLLTDGLLTNGFHSCESDDDDRTSHASSSDWTPRPRIGPYTFVQQHLMIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRILQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLGGEYAKLCCNPVKLSEITEKPPRPQKELVHLSELPPTPLHISEDSSSPERTVPQDSSVIATLVDQATNNNVNDLEVSESSCVEEKPQEVQTSRNVENINVENPDFKAVGSSTADKNERTSVAETVRKCWPNRLAKEQISKRLEGNQYLFVPPNRYIFHGAEVYSDSEDDVLSSSSCGSNSDSGTCQSPSLEEPLEDESEIEEFYNGLEDDTERPECAGGSGFGADGGDQEVVNEAIATRQELTDVNYPSDKS
What is the function of this protein?
Catalytically inactive 75SirT1 may be involved in regulation of apoptosis.  May be involved in protecting chondrocytes from apoptotic death by associating with cytochrome C and interfering with apoptosome assembly.
What are the official names of this protein?
NAD-dependent protein deacetylase sirtuin-1, NAD-dependent protein deacylase sirtuin-1, Regulatory protein SIR2 homolog 1, SIR2-like protein 1, SIR2alpha, Sir2, mSIR2a.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class I subfamily.
What are the subcellular locations of this protein?
Nucleus, PML body. Cytoplasm. Nucleus. Note=Colocalizes in the nucleus with XBP1 isoform 2. Recruited to the nuclear bodies via its interaction with PML. Colocalized with APEX1 in the nucleus. May be found in nucleolus, nuclear euchromatin, heterochromatin and inner membrane (By similarity). Shuttles between nucleus and cytoplasm (PubMed:17197703). SUBCELLULAR LOCATION: [SirtT1 75 kDa fragment]: Cytoplasm. Mitochondrion.
Protein: RSMA_RIPO1
Sequence: MPQPRKRFAQHWLRSETALDQIIEAAQLNMSDLVLEIGPGTGILTRRLLPLVQSIVAVELDRDLCYRLAKSFGNFNHFLLLEGDILSLDLTTQLEQFPQFQPINKVVANIPYNITSPILEKLLGSIAHPQHPSYELIVLLMQKEVAQRIVASPQSKAYGALSVRTQYLAQCDYICEVPSKAFDPPPKVDSAVIRLTPRSLETPAINPQKLDQLVKLGFANRRKMLHNNLKSIIDKDHLTLLLDQLQINPQVRAEELSLEQWIMFSNLLETVS
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGLR1_MAIZE
Sequence: MACTNNAMRALFLLVLFCIVHGEKEESKGIDAKASGPGGSFDITKLGASGNGKTDSTKAVQEAWASACGGTGKQTILIPKGDFLVGQLNFTGPCKGDVTIQVDGNLLATTDLSQYKDHGNWIEILRVDNLVITGKGNLDGQGPAVWSKNSCTKKYDCKILPNSLVMDFVNNGEVSGVTLLNSKFFHMNMYRCKDMLIKDVTVTAPGDSPNTDGIHMGDSSGITITNTVIGVGDDCISIGPGTSKVNITGVTCGPGHGISIGSLGRYKDEKDVTDINVKDCTLKKTMFGVRIKAYEDAASVLTVSKIHYENIKMEDSANPIFIDMKYCPNKLCTANGASKVTVKDVTFKNITGTSSTPEAVSLLCTAKVPCTGVTMDDVNVEYSGTNNKTMAICTNAKGSTKGCLKELACF
What is the function of this protein?
May function in depolymerizing pectin during pollen development, germination, and tube growth.  Acts as an exo-polygalacturonase.
What are the official names of this protein?
Exopolygalacturonase, ExoPG, Galacturan 1,4-alpha-galacturonidase, Pectinase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted. Secreted, cell wall.
Protein: FLAA_HELPJ
Sequence: MAFQVNTNINAMNAHVQSALTQNALKTSLERLSSGLRINKAADDASGMTVADSLRSQASSLGQAIANTNDGMGIIQVADKAMDEQLKILDTVKVKATQAAQDGQTTESRKAIQSDIVRLIQGLDNIGNTTTYNGQALLSGQFTNKEFQVGAYSNQSIKASIGSTTSDKIGQVRIATGALITASGDISLTFKQVDGVNDVTLESVKVSSSAGTGIGVLAEVINKNSNRTGVKAYASVITTSDVAVQSGSLSNLTLNGIHLGNIADIKKNDSDGRLVAAINAVTSETGVEAYTDQKGRLNLRSIDGRGIEIKTDSVSNGPSALTMVNGGQDLTKGSTNYGRLSLTRLDAKSINVVSASDSQHLGFTAIGFGESQVAETTVNLRDVTGNFNANVKSASGANYNAVIASGNQSLGSGVTTLRGAMVVIDIAESAMKMLDKVRSDLGSVQNQMISTVNNISITQVNVKAAESQIRDVDFAEESANFNKNNILAQSGSYAMSQANTVQQNILRLLT
What is the function of this protein?
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.  Important for motility and virulence (By similarity).
What are the official names of this protein?
Flagellin A.
What is the protein family that this protein belongs to?
Belongs to the bacterial flagellin family.
What are the subcellular locations of this protein?
Secreted. Bacterial flagellum.
Protein: NU4LM_CAPMR
Sequence: MTLIHMNIIMAFSMSLVGLLMYRSHLMSALLCLESMMLSLFILATLTVLNSHFTLANIMPIILLVFAACEAAIGLALLVMISNTYGTDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RS9_CHLCV
Sequence: MVKNTIEESVATGRRKQAVSSVRLRPGTGKIDVNGKAFEEYFPLEIQRVTILSPLMKVLGTTNECDLIIRINGGGIQGQVIATRLGLARALLKKNVDSKQELKSHGFLTRDPRKKERKKYGHKKARKSFQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: NEKL2_CAEEL
Sequence: MDNYEKVRVVGRGAFGVCWLCRGKNDASHQKVIIKLINTHGMTEKEENSIQSEVNLLKKVQHPLIIGYIDSFIMDNQLGIVMQYAEGGTLERLINDQRAIKDSNMREYFPEKTVLDYFTQILIALNHMHQKNIVHRDLKPQNILMNRRKTVLKLSDFGISKELGTKSAASTVIGTPNYLSPEICESRPYNQKSDMWSLGCVLYELLQLERAFDGENLPAIVMKITRSKQNPLGDHVSNDVKMLVENLLKTHTDKRPDVSQLLSDPLVLPYLISIHCDLGRIEPPPTDKRKPSASLSSRLRTYPTQSTLRPYSLSSNAPTTHLTQLTPMPSHIDSGFFSSGRTSNQRTQSRSQVHSKY
What is the function of this protein?
Probable serine/threonine-protein kinase required for the completion of molting.  May play a role in endocytosis in the hypodermis syncytium.
What are the official names of this protein?
Serine/threonine-protein kinase nekl-2, Never in mitosis A kinase-like 2, NimA-kinase-like 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=In hyp7 syncytium, localizes in puncta and small tubules near the plasma membrane apical region. Does not co-localize with nekl-3.
Protein: VF345_ASFK5
Sequence: METFVRLFKDSPQQRSNAWHATRRTQVGGSDLASVLGLNPYKSYYITLAEKANLFKKNLNHAACNWGTLFERVSKDLLELFCQTTVIGDNIHIDGTYLGYPGHSNSPDGFCYLTLGYTQQSWEIKTIFNDVCYETTKRIPVLVEIKSPFNRKIKNSVPSYYVPQIQSGLALSPPISMAIYVEAMFRVCGIHQLGWNNETNTDIHPPESMLPLAWGIITICSTQEYTEAPQDFGTLNAETFHQFLETLYQKDQYTIHYSTPYETACPEMSNVVGYFGWKVFIFQIIPVMKHPQFLKDKYPIIQQFLHDLHTIQTSPSPMEAYEKICCTKESPLSTEDIDDFTNMLT
What is the function of this protein?
Plays a role in the negative regulation of host NF-kappa-B signaling pathway.  Mechanistically, recruits IKKA/CHUK and IKBKB to suppress their kinase activity towards NFKBIA.
What are the official names of this protein?
Protein D345L, pD345L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus D345L family.
Protein: NCAP_PHODV
Sequence: MASLLKSLSLFKKTREQPPLASGSGGAIRGIKHVIIVLIPGDSSIVTRSRLLDRLVRMVGDPEVSGPKLTGVLISILSLFVESPGQLIQRIIDDPDISIKLVEVIPSINSTCGLTFASRGASLDAEADEFFGTMDEGSKDHNQMGWLENKDIIDIEVNDAEQFNILLASILAQIWILLAKAVTAPDTAADSEMRRWIKYTQQRRVIGEFRMNKIWLDIVRNRIAEDLSLRRFMVALILDIKRSPGNKPRIAEMICDIDNYIVEAGLASFILTIKFGIETMYPALGLHEFSGELTTIESLMVLYQQMGETAPYMVILENSVQNKFSAGSYPLLWSYAMGVGVELENSMGGLNFGRSYFDPAYFRLGQEMVRRSAGKVSSTFAAEFGITKEEAQLVSEIVSRTTEDRTTRATGPKQSQITFLHSERNEAPNQRLPPITMKSEFQGGDKYSNQLIDDRLSGYTSDVQSSEWDESRQITQLTQEGDHDNDQQSMDGLAKMRQLTKILNQSDTNGEVSPAHNDRDLLS
What is the function of this protein?
Encapsidates the genome, protecting it from nucleases.  The nucleocapsid (NC) has a helical structure.  The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication.  During replication, encapsidation by N is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, NP, Protein N.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses nucleocapsid family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: DEF_BRUSU
Sequence: MSVKPLIILPDPVLRQVSKPVERFDDQLRKFASDMFDTMYDAPGIGLAAIQVGEPIRMLVIDLAKEGEPKAPHIFVNPTIVQSSDKRSTYEEGCLSIPDYYAEVERPATVKVNYFDADGKPQSMEADGLMATCLQHEIDHLNGVLFIDHISKLKRDMVIKKFKKLASQRASKKVL
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: RS17_BIFLO
Sequence: MAEERNFRKVRRGYVVSDKMDKTITVELEQRSTHPLYGKVVRSTSKVKAHDEHNDAHIGDLVSIMETRPLSKTKRWRLESIIERAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: CL071_HUMAN
Sequence: MAYSSSNSDIEDDSSKSNSNLSLSVGYFPCEDTPCEDTTSWEDAPSKGPSIHFLPPVQGAWGTERIGRRMKRQDQIQDEPEQFCKLSIFLAWDVDIGSDNTDSRANRLLNGDNLWIDKLPKERTKLSVGKLNNLVQEFQIFLENLKDDDAVFPETAQQDFQLSSGSPPEMVQMISQATASQRTSAPEISSILSEQPEKDDTPSHTQAQCCLNFGWAFSWLRQRILPSLLRRDHPVNATKSPHRSAPTKRLFHRGKRIQPQETLELGHPI
What are the official names of this protein?
Uncharacterized protein C12orf71.
Protein: CYDA_ECOL6
Sequence: MLDIVELSRLQFALTAMYHFLFVPLTLGMAFLLAIMETVYVLSGKQIYKDMTKFWGKLFGINFALGVATGLTMEFQFGTNWSYYSHYVGDIFGAPLAIEGLMAFFLESTFVGLFFFGWDRLGKVQHMCVTWLVALGSNLSALWILVANGWMQNPIASDFNFETMRMEMVSFSELVLNPVAQVKFVHTVASGYVTGAMFILGISAWYMLKGRDFAFAKRSFAIAASFGMAAVLSVIVLGDESGYEMGDVQKTKLAAIEAEWETQPAPAAFTLFGIPDQEEETNKFAIQIPYALGIIATRSVDTPVIGLKELMVQHEERIRNGMKAYSLLEQLRSGSTDQAVRDQFNSMKKDLGYGLLLKRYTPNVADATEAQIQQATKDSIPRVAPLYFAFRIMVACGFLLLAIIALSFWSVIRNRIGEKKWLLRAALYGIPLPWIAVEAGWFVAEYGRQPWAIGEVLPTAVANSSLTAGDLIFSMVLICGLYTLFLVAELFLMFKFARLGPSSLKTGRYHFEQSSTTTQPAR
What is the function of this protein?
A terminal oxidase that produces a proton motive force by the vectorial transfer of protons across the inner membrane.  It is the component of the aerobic respiratory chain of E. coli that predominates when cells are grown at low aeration.  Generates a proton motive force using protons and electrons from opposite sides of the membrane to generate H(2)O, transferring 1 proton/electron.
What are the official names of this protein?
Cytochrome bd-I ubiquinol oxidase subunit 1, Cytochrome bd-I oxidase subunit I, Cytochrome d ubiquinol oxidase subunit I.
What is the protein family that this protein belongs to?
Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AXIN1_DANRE
Sequence: MSMSVNEKGICYLPDLGSSFTEDAPRPPVPGEEGDLVSSDGRQYNHSFYSSKSDSLKNEASIATPRRPDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGIHLFRTFLKQEECADMLDFWFACSGFRKQEANDGNEKMLKLAKAIYKKYILDNNGIVSRQIKPATKSFIKDCVTKLHIDPAMFDQAQTEIQTMMEENTYPLFLKSDIYLEYTRTGGESPKLFSDQSSVSGNGKVLPGYLPTVIEDVEWRCDQEEEQIAESDPTPSNRLTQKLPLETVPQRVANSKRYQDNREYRHASWREPVNPYYVNSGYALAPATSANDSEQQSMSSDADTLSLTDSSVDGVPPYRYRKPHRREIHESAKVNGRVPLPHIPRTNRIPKDIHVEPEKFAAELISRLEGVLREREAQEKLEERLKRVRLEEEGDDADISTGPSLANHRVPPAVHVQHYGGRYSEMSYNGLQLRDAHEENPESILDEHVQRVMKTPGCQSPGTGRHSPKSRSPDGLPAGKIPGLMMPLSGGQGKHQARQGPKGEAAHLHHHKHIHHTHYAAAGKPKEQAEAEAARMHGGFAWNTEQHHYGPKSRNYADGMSVGPNTMDPMGYSSKGSTLSKRPVRKGEDGRNFEMREPLPADDMERNQKILQWMMEGEKEAGRYKRGPYGSISGPKKAQGHEPARPSSVERLGAVHPWVTAQLRNNVQPSHPFIQDPTMPPNPAPNPLTQLEEARRRLEEERRKSGTLQAKQRHKNMKKQPCENITVAYYFRGEPIPYRTSVKGRIVTLGQFKELLTKKGSYKYYFKKVSYEFDCGVVFEEVREDDAILPIFEEKIIGKVEKVD
What is the function of this protein?
Component of the beta-catenin destruction complex required for regulating ctnnb1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling (PubMed:17681137).  Controls dorsoventral patterning via two opposing effects: down-regulates ctnnb1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway (PubMed:17681137, PubMed:30467143).
What are the official names of this protein?
Axin-1, Axis inhibition protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Membrane. Cell membrane.
Protein: CCA_PSEPF
Sequence: MQIYKVGGAVRDRLLGKPVTDIDWVVVGATTEEMLAKGFRPVGADFPVFLHPKSGEEYALARTERKSGRGYGGFTFHASPEVTLEEDLIRRDLTINAMAEDDQQNLTDPYHGQRDLEERILRHVSPAFAEDPLRVLRVARFAARYAELGFKVAPETLELMRQLSESGELEALTAERSWKEISRALMEDQPQVFIQVLRDCGALKVLMPEVDALFGVPQPEAHHPEIDSGLHTLSVLEQSALHKQPLTVRWACLLHDLGKGLTPEEEWPRHIAHEHKGLKLIKAVNERFKAPKDCQELALLVGQYHTHGHRALELKASTLLELLQSFDVYRRPQRFEEFIVACEMDARGRKGLEQRSYPQADYLRGAANVARGVAVQPLLEKGFKGPELGEALKRERLKALKVYKESAAS
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: PSAL_TRICV
Sequence: MANFIKPYNDDPFVGHLATPITSSSITRAILKNLPAYRFGLTPLLRGLEIGLAHGYFLMGPFVKLGPLRNSDIALFSGFLSTIGLILILTLGLTIYGVAAFGQGQTTENSNDLQTKKAWDQFKGGFFVGACGSAGFALICLSSIPAFTIS
What are the official names of this protein?
Photosystem I reaction center subunit XI, PSI subunit V, PSI-L.
What is the protein family that this protein belongs to?
Belongs to the PsaL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RS11_MOOTA
Sequence: MPPRKTARPRRRDRKHIESGIAHIKSTFNNTLVTITDKNGNAISWASAGTVGFKGSRKSTPFAAQMAAEAAAKQAMEHGLREVECYVKGPGAGREAAIRSLQAAGLEVSVIKDVTPIPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: CDH_SALTI
Sequence: MKKTGYFLLAVIVIVAAAGVGYWKFSGNPDALREIVLERCLPDQLQHQNPAPCAEVKPRAGYVIFKDRHGPLQYLLMPTYRINGTESPLLLEPATPNFFWLAWQARGYMSKKYGHDIPDSAVSLAINSRLGRSQDHLHIHISCIRPDVREQLDNDLTRISTRWLPLPGDLMGHEYLARRVTESELAQRSPFMMLAEEVPEARDHMGRYALAVVRQSDDSFVLLATERNLLTLNRASAEEIQDHSCAILSSR
What are the official names of this protein?
CDP-diacylglycerol pyrophosphatase, CDP-diacylglycerol phosphatidylhydrolase, CDP-diglyceride hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Cdh family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: NU4C_PROM0
Sequence: MLGAGLSNFPWLSASILFPIGSAFVIPFFPDKGDGKEVRWFALSIALITFLITVGSYINGFDINNENVQLKENISWLPDLGLTWSVGADGMSMPLILLTSFITALAVLAAWPVKFKPKLFFFLILVMDGGQIAVFAVQDMLLFFLTWELELIPVYLLLAIWGGKNRQYAATKFIIYTAGSSIFILLAALAMGFYGTEIPNFEFSHLAAQDFNQKFQIFCYVGLLIAFGVKLPIVPLHTWLPDAHGEATAPVHMLLAGILLKMGGYALLRFNAQLLPVAHAQFAPLLIVLGVVNIIYAALTSFAQRNLKRKIAYSSISHMGFVLIGIGSFSSLGTSGAMLQMVSHGLIGASLFFLVGATYDRTKTLKLDEMSGVGQKMRIMFALWTACSLASLALPGMSGFVSELMVFTGFVTDEVYTLPFRVVMASLAAIGVILTPIYLLSMLREIFFGKENPKLIEERKLIDAEPREVYIIACLLLPIIGIGLYPRLVTESYIASINNLVDRDLTAVKSAVKTNIFSGTKTNDILKAPTI
What is the function of this protein?
NDH-1 shuttles electrons from NAD(P)H, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase chain 4, NAD(P)H dehydrogenase I, chain 4, NDH-1, chain 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: KDUI2_RHIME
Sequence: MTASHIDYTIRYAVDPAAAARMDTDALRANFHIGDLFRQGRISLTYSHYDRMIVGGAMPVDKPLALETIRPTGTARFLERRELIAVNIGGPGRIEMNGESFRLEPRDMAYAGMGEDVTFSSEDPAVPAKFYLLSAPAHQALPRRHIRIGDAKRLDLGSAATSNERSIFQFIHPEGVKTCQLVVGMTQLAPGSVWNTMPCHVHDRRMEAYLYFDLDDSARVLHLMGEPSETRHIVMAREEAVLSPPWSIHSGCGTANYAFIWAMAGDNIDYTDVEMVPMETLR
What is the function of this protein?
Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.
What are the official names of this protein?
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase 2, 5-keto-4-deoxyuronate isomerase 2, DKI isomerase 2.
What is the protein family that this protein belongs to?
Belongs to the KduI family.
Protein: RDRP_RDVA
Sequence: MDLARSDIIPHLLCLFQEIIQANIQKVSEAYDLELKIMNILTLWRNGSDNLISDNDDYMKKGLFFSRSNDPLALQARYAQMYDDLFKLNNYKVPDDVVRKHDTKILDIILKESSVPFWYDISDDEAHESMLPEFRLQDIHEFRLNLKRVAVVPDESEEIQMDESQSDKRRRKKRMEKSRPVWLSGSENDRRIELNDSLKPSQKFETKLSSYLLNRLMNEMNPHYCGHPLPALFVTLIMLKAYSLKNKFFSYGIRYMELVCNEIGGPDLNTRTFPVLFGSDGSFVGTRVYSHYPIKLRMILNDLTYLLTYSDLHKFQEFELDVNDEVLLHMLHSPNDGRQLKKAVTRLNLYYGLKFNPKTTDCGVVNGMDFTHKHPITKTADFTSPVLPMTNSFNKAEICYGHSSKILNRAVFTDTVRGYIREDLKNVADLDLPKLHEHVSKLVDMRVNYTIIYDLMFLRVMLNLGGYSRSNQITDFRKTIDEITKMNEDFLSGADPEKNIDILNAWMAPTMEDCGYRLTKSILFGKFRKAKYPSDLEAKSNIDYYVTARSAGIGNLRISIETDKRKYKVRTTSKSAFVNAMGSGILDVNPVSNEPMMLTDYLLTQTPETRANLEAAIDSGSISDSELMRILGQNSIGSRSTTAWRPVRPIYINVLQAHLAQAFIIGPHINATVNQHESQPTSLWFTGDDLGVGFATLYQNGTADIIAPAIEASSTGKALSVLADCSSWDQTFLTATIIPYYNGIKKALLEYQQADMRNFYMIDSSRTGVPGMKLSEIVDWFNSFQTKRIFNASYLKERHSFVVKYMWSGRLDTFFMNSVQNALITRRIAEEVSLKVSNTGLSWFQVAGDDAIMVYDGSSISTTEQVTRVNEITVRNYEESNHIINPQKTVISHISGEYAKIYYYAGMHFRDPSIQLHESEKDSGASDVTESLRGFGQVIYEYNKRAIGTLRVNALYGRLIAGLAYSVNVRRYDASKRTYANMKYYPPPTSVIAPAAFKGGLGLSFTGLSLNEVLFIKMHLHEAVSQGLHVISMISFEANEVVSNSLSAYYLKDQKDLLRDMKLGKHLEKVKGISFKSSDLAFSGSDFSQGLNLKRESIDKVKLEVSRKSIRDLRSSGISVPSTHAYENLPYASLHQSFKSLKVDRDTSKFTNERLLVSLLEYKSDIPRVSVTSQYPVYDLINISKVDELNVRSGGPVRFISTPIEGKLLEENIGTRQGVQFKNRGYGGSQEVLHFIRSNGLVITEQALIDLIIKSGVLLMINPQRGLIDLFQSLSGDTASSMHLANFFMAEKPHWEDNAISLTIAGSLLENCDSRIENVKNFVSVLATGMQKDLQRMFYYVGFVYYAQRLIWSGGHSSKIFVSIDEDKLADFLRGSKPITRRRKAMAGTKREPINLSANFSYEISEPDREISEYDPLVLCHPLSMPFFGNWQEKYSVMQSDEQM
What is the function of this protein?
RNA-directed RNA polymerase that is involved in both transcription and genome replication.  Together with the capping enzyme P5 and protein P7, forms an enzyme complex positioned near the channels situated at each of the five-fold vertices of the core (By similarity).
What are the official names of this protein?
RNA-directed RNA polymerase P1, Replicase.
What is the protein family that this protein belongs to?
Belongs to the reoviridae RNA-directed RNA polymerase family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=Located inside the inner capsid. Found in the interior of spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: RK20_PAUCH
Sequence: MARVKRGNIARKRRNKILRLARGFRGSNGSLFRTANQRVMKALCNAYRDRRRRKRDFRRLWIARINAASRLNGLSYSRLVGSLKKANIKLNRKMLALLALADPTSFANVVVVAKS
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20, organellar chromatophore.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
What are the subcellular locations of this protein?
Plastid, organellar chromatophore.
Protein: LEUC_SULSY
Sequence: MGMTITEKIIAAHAGRDYVEPGELVTVKVDLAIANDITAPLAIKQLEKYGIDKVHDPNKIALVMDHFFPPKDIMSAQQIKISRDFAKKMGIKNYFEGQDSGVMHTLLPEKGFVVPGDLVIGADSHTCTYGGIGAFSTGVGSTDIAYIWATGETWLRVPESMKFVFYNKPQKWVGGKDFVLTVIGKIGVDGALYKAMEYQGEAIRALDIDNRLTIANMAIEAGGKSGIIEPDEKTVDWVRKRTNREFKLYKSDPDAKYCCEYEFDASKIEPVVACPSLPSNVKPVSEVAGTHIDQVFIGSCTNGRLSDLRIAAAILKSKKVHPEVRCIVIPASDQIYKQALHEGIIEILADAGCLISTSTCGPCLGGHMGILAEGEVCLSTSNRNFVGRMGHPKSQVYLSSPAVAAASAVLGRIAHPDEVAKYEEVETLITL
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
Protein: ENOPH_LACTC
Sequence: MAYAAVLLDIEGTVCPISFVKESLFPFFLKQVDTLCSSQDLQVQRLLTQFQVDDVAGHIRSLVARDVKDPILKQLQGLVWENGYKDGQIKAPVYDDAIKFIKNSDVPVYIYSSGSVKAQKLLFQYVESRSNTLDLRPFIKGYFDINTSGVKTQSESYARIANNVGIKPNGVLFISDNPFELDAAKITGMQTMLAVRPGNSEVRDALKYNPVTNFDDL
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y399_STAAN
Sequence: MCVVYRTSVLILLASGCSGVFDTPEDSKETQIKKSFAKTLDMYPIKNLEDLYDKEGYRDGEFKKGDKGTWVVRSEMIIQPKGKSLTSRGMILYMNRNTRTTTGYFSIEEIDSRKSLDERETEKKYPVKMINNKIIPTEEIKDEKLKKEIENFKFFVQYGSFKGIENYENGDISYNSEAPIYSAKYKLKNDDYNVKELRKRYNIPTEKAPKLLLKGSGDLKGSSVGYKEIEFIFIENKKENIYFSDGLNLIPSD
What are the official names of this protein?
Uncharacterized lipoprotein SA0399.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal tandem lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: SPI2_CRAVI
Sequence: MKVAVVVALLCFVCYTAAETCSADGDCKNTICDASHDLECHRGQCTCVNHATACSSAADCSGSCTIFGRHGRWHCVDAKCRCFFV
What is the function of this protein?
Slow-binding inhibitor of serine proteases.  The inhibitor rapidly binds to the protease forming a weak enzyme-inhibitor complex, and this is followed by a slow isomerization forming a tight-binding enzyme-inhibitor complex.  Active against subtilisin A with a dissociation constant of 0. 18 nM.  Active against perkinsin.  Not active against thermolysin, papain or pepsin.
What are the official names of this protein?
Serine protease inhibitor Cvsi-2.
What are the subcellular locations of this protein?
Secreted.