PharMolix/UniProtQA huggingface dataset:
Protein: Y791_NEIG1
Sequence: MTEQENKTSLIEFPCTFPLKVMGAVHPEFEQAVLETVRLHAPDTQAHHITTRPSSKGNYTGATVQVKVENQEQLDNIYRALTSHELVKVVL
What are the official names of this protein?
UPF0250 protein NGO0791.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.
Protein: TRMB_DEIGD
Sequence: MIFRLADFHFPDSAARLYPDTPQRPWILEVGFGDGRFWPHYAATFPEAPNYLGVEISGVSLLKAERRLREAGLSNAVLTKLPATPLIREVVPAGSLDAIVVNFPDPWPKAGHAEHRLLRAPFFRLAASRLKPGGAVLLTTDHDEYFEFACREAEASGVMRAELTDPPPAALETKYARKWRELGLEVQHARFVPTHHPHVPHGTVARFPDSEDAPAVPHAILTLPAAFDPGAFHKHTARGGQTREDPVGWTVVLLELYRSLKQDGWVMLAHVVEGELTQEVLIGISARGDGSHLVRLASFGGPIITPGVKAAVGVVTDWLEEQGAAVRHRGY
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: SECA_HAEI8
Sequence: MSILTRIFGSRNERVLRKLKKQVVKINKMEPAFEALSDDELKAKTQEFRDRLSGGETLQQILPEAFATVREASKRVLGMRHFDVQLIGGMVLTNRCIAEMRTGEGKTLTATLPCYLIALEGKGVHVVTVNDYLARRDAETNRPLFEFLGMSVGVNIPGLSPEEKRAAYAADITYATNSELGFDYLRDNLAHSKEERFQRTLGYALVDEVDSILIDEARTPLIISGQAENSSELYIAVNKLIPSLIKQEKEDTEEYQGEGDFTLDLKSKQAHLTERGQEKVEDWLITQGLMPEGDSLYSPSRIVLLHHVMAALRAHTLFEKDVDYIVKDGEIVIVDEHTGRTMAGRRWSDGLHQAIEAKEGVDVKSENQTVASISYQNYFRLYERLAGMTGTADTEAFEFQQIYGLETVVIPTNRPMIRDDRTDVMFENEQYKFNAIIEDIKDCVERQQPVLVGTISVEKSEELSKALDKAGIKHNVLNAKFHQQEAEIVAEAGFPSAVTIATNMAGRGTDIILGGNWKAQAAKLENPTQEQIEALKAEWEKNHEIVMKAGGLHIIGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSLEDGLMRIYLNEGKLNLMRKAFTVAGEAMESKMLAKVIASAQAKVEAFHFDGRKNLLEYDDVANDQRHAIYEQRNHLLDNDDISETINAIRHDVFNGVIDQYIPPQSLEEQWDIKGLEERLSQEFGMELPISNWLEEDNNLHEESLCERIVEIAEKEYKEKEALVGEDAMRHFEKGVMLQTLDELWKEHLASMDYLRQGIHLRGYAQKDPKQEYKKESFRMFTEMLDSLKHQVITTLTRVRVRTQEEMEEAERARQEMAARINQNNLPVDENSQTTQNSETEDYSDRRIGRNEPCPCGSGKKYKHCHGSRVARQ
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: MINC_SHEFN
Sequence: MAKQNLELKATSFTLSVLHINHNDLDIIAAELDNKLAQAPQFFLGAPLVLNLSAIQHTHIDFNALKQLLIDRNLIIVGITDASAEQIEQAKSMAIAVVKSGKQARKAELPERATKIVKQNVRSGQQIYAQNADLIIFGAVGNGAEVIADGSIHIYGALRGKAMAGAAGDNQSVIIANSLEAELVSIAGQYWLTEHLQQYDLSQRGCVRLEGASLTVESLPQ
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: ACPS_THEPX
Sequence: MELFVGTDIVEVERIKKAFDANSKFLERLFTQKEIEYFNSKRMKLPHIAGFFSAKESISKVLGTGISGFSWKDIEICHDEKGAPAVILKGKAKNIADKKGIRDIKLSISHTKTYAISCAIAIGGEKNDSADLKTDERS
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNA_METNO
Sequence: MKIDGRPYRTIFPEPGGDAVCVIDQTRLPFAFEIRRLTTAEEAAEAIRTMVVRGAPLIGVTAAYGLALGLRRDPSDAGLERIAAMLAATRPTAVNLRWALERLSGILRPLPPDTRAPQAFAEAGRIAEEDVANCRAIGEHGARLIAQTAAKGRRVNVLTHCNAGWLATVDWGTALAPIYVAHDAGVPVHVFVDETRPRNQGAALTAFELNAHGVPHTVVADNAGGHLMQHGGVDLCIVGSDRTTSTGDVCNKIGTYLKALAAFDNGVPFYAALPVSTIDWTLTDGVAGIPIEERDGREVTHLTGRTEDGGFATIQVVSPGSPVANPAFDVTPARLVTGLITERGVAEATEEGLLRLYPERRKAA
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: IKZF2_MOUSE
Sequence: METDAIDGYITCDNELSPEGEHANMAIDLTSSTPNGQHASPSHMTSTNSVKLEMQSDEECDRQPLSREDEIRGHDEGSSLEEPLIESSEVADNRKVQDLQGEGGIRLPNGKLKCDVCGMVCIGPNVLMVHKRSHTGERPFHCNQCGASFTQKGNLLRHIKLHSGEKPFKCPFCSYACRRRDALTGHLRTHSVGKPHKCNYCGRSYKQRSSLEEHKERCHNYLQNVSMEAAGQVMSHHVPPMEDCKEQEPIMDNNISLVPFERPAVIEKLTANMGKRKSSTPQKFVGEKLMRFSYPDIHFDMNLTYEKEAELMQSHMMDQAINNAITYLGAEALHPLMQHAPSTIAEVAPVISSAYSQVYHPNRIERPISRETSDSHENNMDGPISLIRPKSRPQEREASPSNSCLDSTDSESSHDDRQSYQGNPALNPKRKQSPAYMKEDVKALDATKAPKGSLKDIYKVFNGEGEQIRAFKCEHCRVLFLDHVMYTIHMGCHGYRDPLECNICGYRSQDRYEFSSHIVRGEHTFH
What is the function of this protein?
Associates with Ikaros at centromeric heterochromatin.
What are the official names of this protein?
Zinc finger protein Helios, Ikaros family zinc finger protein 2.
What is the protein family that this protein belongs to?
Belongs to the Ikaros C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TTCA_PSEP1
Sequence: MGTLSVNQNKLQKRLRRLAGEAITDYNMIEDGDKVMVCLSGGKDSYTMLDVLLHLQKVAPITFEIVAVNMDQKQPGFPEHVLPAYLKELGVEYHIVEKDTYSVVKELVPEGKTTCSLCSRLRRGTLYTFADEIGATKMALGHHRDDIVETFFLNMFFNGALKGMPPKLRADDGRNVVIRPLAYCSEKDIQAYSDMKAFPIIPCNLCGSQENLQRQVVKDMLVEWERKHPGRTESIFRALQNVAPSQLADRNLFDFTSLKIDENATPRFLDVLNI
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCUB2_HUMAN
Sequence: MGVAGRNRPGAAWAVLLLLLLLPPLLLLAGAVPPGRGRAAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQCEDIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDCILTCNHGNGGCQHSCDDTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGDKRVKRRLLMETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDHSCINHPGTFACACNRGYTLYGFTHCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNKKDCVEVKGLLPTSVSPRVSLHCGKSGGGDGCFLRCHSGIHLSSDVTTIRTSVTFKLNEGKCSLKNAELFPEGLRPALPEKHSSVKESFRYVNLTCSSGKQVPGAPGRPSTPKEMFITVEFELETNQKEVTASCDLSCIVKRTEKRLRKAIRTLRKAVHREQFHLQLSGMNLDVAKKPPRTSERQAESCGVGQGHAENQCVSCRAGTYYDGARERCILCPNGTFQNEEGQMTCEPCPRPGNSGALKTPEAWNMSECGGLCQPGEYSADGFAPCQLCALGTFQPEAGRTSCFPCGGGLATKHQGATSFQDCETRVQCSPGHFYNTTTHRCIRCPVGTYQPEFGKNNCVSCPGNTTTDFDGSTNITQCKNRRCGGELGDFTGYIESPNYPGNYPANTECTWTINPPPKRRILIVVPEIFLPIEDDCGDYLVMRKTSSSNSVTTYETCQTYERPIAFTSRSKKLWIQFKSNEGNSARGFQVPYVTYDEDYQELIEDIVRDGRLYASENHQEILKDKKLIKALFDVLAHPQNYFKYTAQESREMFPRSFIRLLRSKVSRFLRPYK
What is the function of this protein?
Lipid-binding protein required for SHH long-range signaling by binding to the dually lipid-modified SHH (ShhNp) and by promoting ShhNp mobilization, solubilization and release from the cell membrane (PubMed:22902404, PubMed:22677548).  Acts by enhancing the proteolytic processing (shedding) of the lipid-modified N- and C- terminal of ShhNp at the cell surface (PubMed:24522195).  Synergizes with DISP1 to increase SHH secretion (PubMed:22902404).  Probable cell surface coreceptor for VEGFR2 involved in VEGFR2-mediated angiogenesis (PubMed:27834687).
What are the official names of this protein?
Signal peptide, CUB and EGF-like domain-containing protein 2, Protein CEGP1, Scube/You.
What are the subcellular locations of this protein?
Secreted. Cell surface. Note=Secreted and tethered at the cell surface (PubMed:19480626).
Protein: PUR9_STRP6
Sequence: MTKRALISVSDKSGIIDFAKELKNLGWDIISTGGTKVALDNAGVETIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDVDSHLQAAKDNNIELIDLVVVNLYPFKETILRPDVTYDLAVENIDIGGPSMLRSAAKNHASVTVVVDPADYATVLGELADAGQTTFETRQRLAAKVFRHIAAYDALIAEYFTAQVGEAKPEKLTITYDLKQAMRYGENPQQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDVDAAIRIIRDFKDRPTVVALKHMNPCGIGQADDIETAWDYAYEADPVSIFGGIVVLNREVDAATAKKMHPIFLEIIIAPSYSEEALAILTNKKKNLRILELPFDAQAASEVEAEYTGVVGGLLVQNQDVVAENPSDWQVVTDRQPTEQEATALEFAWKAIKYVKSNGIIITNDHMTLGLGAGQTNRVGSVKIAIEQAKDHLDGAVLASDAFFPFADNIEEVAAAGVKAIIQPGGSVRDQDSIDAANKHGLTMIFTGVRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: MDL1_CAEEL
Sequence: MEQQLNLGHLLTAARLLDIGALDISSLDLGALTSTSSSPGSSSPAMFDLSNESELRSLFCGKLKVDKKQSSCASNASTSSQPYCSSPPARKSSKHSRTAHNELEKTRRANLRGCLETLKMLVPCVSDATRNTTLALLTRARDHIIELQDSNAAQMKKLNDLRDEQDELVAELAQLQADEEVAQATSQACQTLSQSRPESRASSFTSTSSRDSPCYLEYSPSSKPMDSHKPTIIDLYAEGLIPRGPITFPRPLVYPHNVFDLMNLPPTPFDVSQFLPINLQV
What is the function of this protein?
Transcriptional regulator which binds to the E box motif 5'-CACGTG-3', when in a heterodimeric complex with mxl-1 (PubMed:9764821).  Involved in the control of lifespan in response to dietary restriction, the decline in protein homeostasis associated with normal aging, germline signaling and may overlap with the insulin-like signaling pathway (PubMed:24699255, PubMed:27001890).  Plays a role in autophagy (PubMed:27001890).  Involved in promoting infection by the microsporidian pathogen N. parisii, possibly together with transcription factors pha-4 and zip-10 (PubMed:27402359).
What are the official names of this protein?
Mad-like protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: G6PI_METFK
Sequence: MTNPTNCPIWHDLSAHYQEVLPLQMRDMFTKDGRRFEKFSLEAEGLLLDYSKHRITDETLPLLFKLARDSKVEEWRDRMFAGEKINFTENRAVLHTALRNRSNTPVYVDGKDVMPDVNRVLAQMRKFSTSIRSGEWKGYSGKRITDVVNIGIGGSDLGPVMVCGALKPYAQAGLNAHFVSNIDGTHLAQTLERCDPETTLFIVASKTFTTQETMTNARSARSWFLQAAKDEAHVAKHFVAISTNADEVGKFGIDAANMFEFWDWVGGRYSLWSAIGLSIAIYIGMDHFEELLQGGYEIDRHFKNAPLEQNIPVIMALLGIWYNNFFGADSLAILPYDQGLARFPAYLQQADMESNGKFVARDGRIVQCTTGPIIWGEAGTNGQHAFYQLIHQGNRLIPCDFMMPLQSHYSMGKNGNEHHLILLANCFAQTSALMQGKTLDEAKAELVAQGLTGEALETLLPHKVFEGNRPSTTILFDKLTPKTLGKLIAIYEHKIFVQGIIWNINSFDQWGVEYGKQIAKKILPQLSEDQASTEYDSSTNGLMNYFKSRTQSSGT
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_STRP3
Sequence: MRYLTAGESHGPSLTAIIEGIPAGLTLHPADIDHELQRRQGGYGRGARMSIETDRVQISSGVRHGKTTGAPITLTVINKDHQKWLDVMAVGDIEETLKLKRRVKHPRPGHADLVGGIKYHFNDLRDALERSSARETTMRVAVGAVAKRILAELGIDMLHHILIFGGITITIPSKLSFRELQERALHSELSIVNPKQEKEIKTYIDKIKKEGDTIGGIIETIVQGVPAGLGSYVQWDKKLDAKLAQAVLSINAFKGVEFGVGFDMGFQKGSQVMDEITWTPTQGYGRQTNHLGGFEGGMTTGQPLVVKGVMKPIPTLYKPLMSVDIDSHEPYKATVERSDPTALPAAGVIMENVVATVLAKEILETFSSTTMSELQKAFSDYRAYVKQF
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: SSRP_METRJ
Sequence: MAPKPEPSRRIVADNRAARYHYTIEDTLEAGIALTGTEVKSLRGGKATIGEAYAGPSGTDLMLFNAYIPEYLEANRFNHDTKRPRRLLLHRRQINKLIGATQRQGYTVVPLKIYFNDKGRAKVELGLGKGKQAHDKREAVKERDWQRDRARLMRDRG
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: YQGF_DICTD
Sequence: MRVLAIDWGEKYIGLAISDPLRIIAQGLDVWEIKDEEDFVNRLKKLIKEYNVSEIVLGYPISLRGHENEKTKKIEYVAERIKTVVNLPIKFVDERFTTMEAERVLLEGDIKRRDRKLLKNKQAAVIILQKYLDSLSLDTKI
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPZA_ARATH
Sequence: MADEEDELLETELSYDQKKEIAKWFFLNAPAGEINYVAKDLKAVLSDEEVYNEAAMEAFPVYNKTHMICLEMPSGAGDVIVSSYSEINENEYLDPRTAQVAIVDHVKQICTKVRPANDEELPSLYIEEYRYALDAEIQRYVSESYPKGMSAVNCVKGKDNEGPGSDFELVVIITAMRLSPQNFCNGSWRSVWNIDFQDESQVLDIKGKLQVGAHYFEEGNVELDAKKDFQDSTIFQSADDCAIAIANIIRHHETEYLASLEVAYSKLPDNTFKDLRRKLPVTRTLFPWQNTLQFSLTREVEKELGLGK
What is the function of this protein?
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends.  Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity).
What are the official names of this protein?
F-actin-capping protein subunit alpha, CapZ alpha.
What is the protein family that this protein belongs to?
Belongs to the F-actin-capping protein alpha subunit family.
Protein: DEF58_ARATH
Sequence: MNITKRYVVIFFLVMLTKSLSNSDVLVSSVIETSKNDVCFIPCTRRYGDWECYDDCLGKNFNDGGCVDGRCCCKK
What are the official names of this protein?
Defensin-like protein 58.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y534_KINRD
Sequence: MVRLAPEERRREARAARAAYRAGRRGPTSGVAPGMTQANLVAVPADWAFDVLLYAQRNPRACPVLDVLEAGRVESALAPGSDVRTDLPAYLVFRDGVVVEEVPDATGYWDDLVTLLIGCSFTFETPLLAAGIPVRHQELGRNVPMYRTDRPCAPAGRLRGDLVVSMRPVPADRVADAVAITGRFPAVHGAPVHVGDPAALGIASLDSPDFGDPPVVRDGEVPVFWACGVTPQAALFASRPPFAVTHAPGHMFVTDVLDSEYDVTGVS
What are the official names of this protein?
Putative hydro-lyase Krad_0534.
What is the protein family that this protein belongs to?
Belongs to the D-glutamate cyclase family.
Protein: TIG_GLUDA
Sequence: MQVTETLSAGLKRGFTVTVPAGELESKRTARLKELGQSMNLPGFRPGKVPLSIVKQRYGDAVQGEVLEQAVSDATRALMDERGLRPAMQPRVDLVAGAEPGGKADLEFKVEVELLPDIAQPDLSTLSLTRLKATPDAETIDKALKDIASRQRDFETIEDVRPAAQGDVVVVDFVGKVDGVAFEGGTAQDVNVELGGAGFIPGFAEQIEGMSPGEEKVITVTFPADYSAENLAGKEATFDITAKALKRPVDVEIDDEMAKKIGFEGLEQVRELITRQVEQEYEQLSRLRIKRELLDALAEKTDFEAPQGMVEAEFAQIWQRVEADRKAGELDEEDKEKDEDTLRADYRKIAERRVKLGLLLAEIGRANAITVSQDEMLQAIRAEAMRYPGQEQQVFEFFRKNPQAAESLRGPIFENKVVDYVIELATVEDKDVTPEELAEIPPADL
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: CCL4_HUMLU
Sequence: MEDLKPRPASSSPLTPLGFLERAATVYGDCTSVVYDAVSYTWSQTHRRCLCLASSIASLGIENGHVVSVLAPNVPQMYELHFAVPMAGAILNAVNLRLDARTISILLHHSESKLIFVDHLSRDLILEAIALFPKQAPVPRLVFMADESESGNSSELGKEFFCSYKDLIDRGDPDFKWVMPKSEWDPMILNYTSGTTSSPKGVVHCHRGIFIMTVDSLIDWGVPKQPVYLWTLPMFHANGWSYPWGMAAVGGTNICLRKFDSEIIYDMIKRHGVTHMCGAPVVLNMLSNAPGSEPLKTTVQIMTAGAPPPSAVLFRTESLGFAVSHGYGLTETAGLVVSCAWKKEWNHLPATERARLKSRQGVGTVMQTKIDVVDPVTGAAVKRDGSTLGEVVLRGGSVMLGYLKDPEGTAKSMTADGWFYTGDVGVMHPDGYLEIKDRSKDVIISGGENLSSVEVESILYSHPDILEAAVVARPDEFWGETPCAFVSLKKGLTKKPTEKEIVEYCRSKLPRYMVPKTVVFKEELPKTSTGKVQKFILRDMARGMGSATAGASRSRM
What is the function of this protein?
Involved in the biosynthesis of prenylated phenolics natural products which contribute to the bitter taste of beer and display broad biological activities (Probable).  Catalyzes the ligation of CoA on 2-methylpropanoate (isobutyric acid) and 2-methylbutanoate to produce 2-methylpropanoyl-CoA and 2-methylbutanoyl-CoA, respectively (PubMed:23300257).  Can also use propanoate and butanoate as substrates with a lower efficiency (PubMed:23300257).
What are the official names of this protein?
2-methylpropanoate--CoA ligase CCL4, HlCCL4, 2-methylbutanoate--CoA ligase CCL4, Butanoate--CoA ligase CCL3, Propionate--CoA ligase CCL3.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: ZN444_HUMAN
Sequence: MEVAVPVKQEAEGLALDSPWHRFRRFHLGDAPGPREALGLLRALCRDWLRPEVHTKEQMLELLVLEQFLSALPADTQAWVCSRQPQSGEEAVALLEELWGPAASPDGSSATRVPQDVTQGPGATGGKEDSGMIPLAGTAPGAEGPAPGDSQAVRPYKQEPSSPPLAPGLPAFLAAPGTTSCPECGKTSLKPAHLLRHRQSHSGEKPHACPECGKAFRRKEHLRRHRDTHPGSPGSPGPALRPLPAREKPHACCECGKTFYWREHLVRHRKTHSGARPFACWECGKGFGRREHVLRHQRIHGRAAASAQGAVAPGPDGGGPFPPWPLG
What is the function of this protein?
Transcriptional regulator.  Binds to the 5'-flanking critical region of the SCARF1 promoter.
What are the official names of this protein?
Zinc finger protein 444, Endothelial zinc finger protein 2, EZF-2, Zinc finger and SCAN domain-containing protein 17.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PYRG_VIBVY
Sequence: MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLKVTMMKLDPYINVDPGTMSPTQHGEVFVTEDGAETDLDLGHYERFIRTKMTKRNNFTAGRVYSDVLAKERRGDYLGATIQVIPHITNDIKDRVINGSQGHDVAIVEVGGTVGDIESLPFMEAIRQLAVEIGRERAMFMHLTLVPYLAAAGEVKTKPTQHSVKELLSIGIQPDILVCRSDRMIPANERKKIALFCNVPEKAVISMKDVDSIYKIPQLIKSQGLDDLVCARFGINAPEADLSEWEQVIYEEANPTGEVTIGMVGKYIELPDAYKSVNEALKHAGLKNRLSVNIKYVDSQDVETKGVEVLQGLDAILVPGGFGDRGIEGKILAAKYARENKVPYLGICLGMQVALIEYARNVAGMEGAHSTEFNKDTKYPVVGLITEWVDSEGNVEERTESSNLGGTMRLGSQLCHLAKGTKARELYGSDTIHERHRHRYEVNNNLRPQIEKAGLKVSGLSADKKLVEMIENPNHPWFVAAQFHPEFTSTPRDGHPLFSGFIKAAGENARGELK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: DXS_THEVB
Sequence: MHLSELTHPNQLHGLSIAQLTQIAAQIRDKHLETVAATGGHLGPGLGVVELTLALYQTLDLEKDRVVWDVGHQAYPHKMLTGRYNNFHTLRQKGGIAGYLNRRESPFDHFGAGHASTSISAALGMAIARDLKGENFKVVAIIGDGALTGGMALEAINHAGHLPHTNLMVVLNDNEMSISPNVGAIPRYLNKIRLSPQVQFITDNLEEQFKHIPFFGENLTPEMQRLKEGMKRLAVPKVGAVFEELGFTYVGPVDGHNLEELIATFQHAHTIPGPVLVHVATVKGKGYAIAEKDQVGYHAQNPFDLVTGKAKPSSKPKPPSYSKVFGETLTKLAENDPRIVGITAAMATGTGLDILQKRVPKQYIDVGIAEQHAVTMAAGMATQGMRPVAAIYSTFLQRAYDQIVHDVCIQKLPVFFCMDRAGIVGADGPTHQGMYDIAYLRCLPNMVLMAPKDEAELQRMIVTGINYTDGPIALRYPRGNGYGVALMEEGWEPLEIGKGELLRSGEDLLLVAYGSMVYPAMQVAEILKEHGMSAAVINARFAKPLDTELILPLAKQIGRVVTLEEGCLMGGFGSAVLEALQEADILVPVLRLGVPDILVEHASPDESKADLGLTPPQMAETIMQKFGVPQRATVVTAS
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: TUSB_SALG2
Sequence: MLHTLPHCASSVDFPALLRLLKEGDALLLLQDGVTVAIEGNRFLESLRDAPITVYALKEDIDARGLGGQISDSVVRVDYTDFVRLTVKYANQMAW
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
What are the official names of this protein?
Protein TusB, tRNA 2-thiouridine synthesizing protein B.
What is the protein family that this protein belongs to?
Belongs to the DsrH/TusB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1390_STRR6
Sequence: MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRARLPVKLIYAQGFASKEEAMSAEALFKRKKRPQKEEFLSENQDRNLLSYFEESWGVL
What are the official names of this protein?
UPF0213 protein spr1390.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: Y3156_ALBFT
Sequence: MDTRLLELLVCPVTKGPLEYNREKQELTSRSARLAYPVRDGVPILLESEARTLSDEELGL
What are the official names of this protein?
UPF0434 protein Rfer_3156.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: PPDPF_RAT
Sequence: MAAIPSSGSLVATHDYYRRRLGSSSSNSSGGSAEYPGDAVPHSPGLPKADSGHWWASFFFGKSTLPFMAAVLESPEHSAESPQASRSPISCGLAPETMKKQPVMHPSQTNSRAPS
What is the function of this protein?
Probable regulator of exocrine pancreas development.
What are the official names of this protein?
Pancreatic progenitor cell differentiation and proliferation factor, Exocrine differentiation and proliferation factor.
What is the protein family that this protein belongs to?
Belongs to the PPDPF family.
Protein: FOLT_STRMU
Sequence: MNTMFKSPKLSPQRLVTLAMLIALAFAIGKLSIPIIPQQLIISPTFIVNVMIGMIGGPIWAFISLAILDIVDNLSSGAGNFIIWWTLLEAVQGLFYGLFFYQKSLSWTNKKDWLHVTIATAIIMLIGSFIFTPLLVQIYYGVPFWAQFAAGRWLKIFEIPIRILVTMAIMPQLQRIPELRKLANFK
What is the function of this protein?
Folate-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.  The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins (By similarity).
What are the official names of this protein?
Folate transporter FolT, Folate ECF transporter S component FolT.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.