PharMolix/UniProtQA huggingface dataset:
Protein: TRM51_ARATH
Sequence: MFDESKFDVNLKLWALRIPRELCKSASRILNGYMLNMPRIKPITEDPTCEKTRLVILSESVKNADLSEIPEEKLNQLKKLSELEVVPHSVTLGYSYWSADHLLKQILPDGLDIPSSFETIGHIAHLNLHDELLPFKDVIAKVIYDKNYPRIKTIVNKVGTISNEFRVPKFEVLAGENGMETEVKQYGARFKLDYGLVYWNSRLEHEHMRLSSLFKPGETVCDMFAGIGPFAIPAAQKGCFVYANDLNPDSVRYLKINAKFNKVDDLICVHNMDARKFFSHLMAVSTCEDNLQSVADNDKTKEAAVSRGGETNSSGEEIRESNASINEPLGANKKPSGTTKTENGVGKDCKSIEGHANKRLRQTLLPIAKPWEHIDHVIMNLPASALQFLDSFSNVIQKKYWKGPLPLIHCYCFIRASETTEFIIAEAETALKFHIEDPVFHKVRDVAPNKAMFCLSFRLPEACLKQEE
What is the function of this protein?
Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs.  Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside.  This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.
What are the official names of this protein?
tRNA (guanine(37)-N1)-methyltransferase 1, M1G-methyltransferase 1, tRNA [GM37] methyltransferase 1, tRNA methyltransferase 5 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Nucleus. Cytoplasm. Note=Predominantly in the mitochondria and in the nucleus.
Protein: MATK_CUCSA
Sequence: MEEFQGYLELEKSRQRDFLYPLIFREYIYAFSHDHFLNGSILLENSGYDKKSSLLMVKHLITRMYHQNHFFFFTNYYNKNPFWGYNNNLYSQMLSEGFAVIVEIPLSLRLVSSLEEEEIAKSYNLRSSHSIFPFLEDKFPHLNYVSDVLIPYPLHLEILVQILRSWVKDASSFHLLRFFFHEYCNLNSLSTSKKLISFFSKRNRRLVLLLYNSYVCEYESIFLFLRNQSSHIRLTSYKGLFERIYFYGKIEHLVKVFANYFSAILRVFKDPLIHYVRYQAKSILVSKDTPLLINKWKYYLVNLWQCHFYVWSQPERIYINQLSKRSLDFLGYISSVRLNPSVVWTQMLENSFLIDNATQKLDTLVPIITLLASLAKAKFCNVLGHPISKPTWIDSSDFDIIDRFLRISRNLSHYYRGSSKKKNLYRIQYILRLSCVKTLARKHKSTVRALFKRLNSELLEEFFTEQEQVLSLIFPRTSFTLRRVYRGKIWYLDIICMNDLANHE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y2876_MYCTO
Sequence: MFGQWEFDVSPTGGIAVASTEVEHFAGSQHEVDTAEVPSAAWGWSRIDHRTWHIVGLCIFGFLLAMLRGNHVGHVEDWFLITFAAVVLFVLARDLWGRRRGWIR
What are the official names of this protein?
Uncharacterized protein MT2944.1.
What is the protein family that this protein belongs to?
To M.leprae ML1584.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MIAB_STAA9
Sequence: MNEEQRKASSVDVLAERDKKAEKDYSKYFEHVYQPPNLKEAKKRGKQEVRYNRDFQIDEKYRGMGNERTFLIKTYGCQMNAHDTEVIAGILEALGYQATTDINTADVILINTCAIRENAENKVFSEIGNLKHLKKERPDILIGVCGCMSQEESVVNKILKSYQNVDMIFGTHNIHHLPEILEEAYLSKAMVVEVWSKEGDVIENLPKVREGNIKAWVNIMYGCDKFCTYCIVPFTRGKERSRRPEDIIDEVRELAREGYKEITLLGQNVNSYGKDLQDIEYDLGDLLQAISKIAIPRVRFTTSHPWDFTDHMIDVISEGGNIVPHIHLPVQSGNNAVLKIMGRKYTRESYLDLVKRIKDRIPNVALTTDIIVGYPNESEEQFEETLTLYDEVGFEHAYTYLYSQRDGTPAAKMKDNVPLNVKKERLQRLNKKVGHYSQIAMSKYEGQTVTVLCEGSSKKDDQVLAGYTDKNKLVNFKAPKEMIGKLVEVRIDEAKQYSLNGSFVKEVEPEMVIQ
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CNGA1_HUMAN
Sequence: MKNNIINTQQSFVTMPNVIVPDIEKEIRRMENGACSSFSEDDDSASTSEESENENPHARGSFSYKSLRKGGPSQREQYLPGAIALFNVNNSSNKDQEPEEKKKKKKEKKSKSDDKNENKNDPEKKKKKKDKEKKKKEEKSKDKKEEEKKEVVVIDPSGNTYYNWLFCITLPVMYNWTMVIARACFDELQSDYLEYWLILDYVSDIVYLIDMFVRTRTGYLEQGLLVKEELKLINKYKSNLQFKLDVLSLIPTDLLYFKLGWNYPEIRLNRLLRFSRMFEFFQRTETRTNYPNIFRISNLVMYIVIIIHWNACVFYSISKAIGFGNDTWVYPDINDPEFGRLARKYVYSLYWSTLTLTTIGETPPPVRDSEYVFVVVDFLIGVLIFATIVGNIGSMISNMNAARAEFQARIDAIKQYMHFRNVSKDMEKRVIKWFDYLWTNKKTVDEKEVLKYLPDKLRAEIAINVHLDTLKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYIIKEGKLAVVADDGVTQFVVLSDGSYFGEISILNIKGSKAGNRRTANIKSIGYSDLFCLSKDDLMEALTEYPDAKTMLEEKGKQILMKDGLLDLNIANAGSDPKDLEEKVTRMEGSVDLLQTRFARILAEYESMQQKLKQRLTKVEKFLKPLIDTEFSSIEGPGAESGPIDST
What is the function of this protein?
Subunit of the rod cyclic GMP-gated cation channel, which is involved in the final stage of the phototransduction pathway.  When light hits rod photoreceptors, cGMP concentrations decrease causing rapid closure of CNGA1/CNGB1 channels and, therefore, hyperpolarization of the membrane potential.
What are the official names of this protein?
cGMP-gated cation channel alpha-1, Cyclic nucleotide-gated cation channel 1, Cyclic nucleotide-gated channel alpha-1, CNG channel alpha-1, CNG-1, CNG1, Cyclic nucleotide-gated channel, photoreceptor, Rod photoreceptor cGMP-gated channel subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family. CNGA1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATP8_SHEEP
Sequence: MPQLDTSTWLTMILSMFLVLFIIFQLKISKHNFYHNPELMTTKTPKQNTPWETKWTKIYLPLSLPL
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: DNAA_OENOB
Sequence: MKDSYFDLNTFWKGIQGRFAANMGETAYENWIKPVRAVKVDLANRTVELQAPNDIVMQAWDNGNYTAKFMEYAYDVAHDFFKPELKVIKVVANPVNNQKSNQSNSDFVATDYQLNQNFTFDTWVIGDANELATSAAMAVSEQPGRQYNPLLIYGSSGLGKTHLMEAIGNRLKELQPDAIVRYITTDDFMNDWVNAISKKTTADFTSTYENVDLLLVDDIQMLQGKDRFQEEFFNIFNKITKSQKQIVMTSDVLPKDIPGLNARLVSRFMQGVAYDIQKPDFPTRLAILKNKSEEVGISIDNQTLTLIAEQIDTNVRELEGAFNTLTLMARAGRPINVSNAQKILEHLNITRQKVITLPDIQKTVADDYNVSINDLIGKKRNSDIVLPRQVAMYLIRTLTDTSLPKIGQAFGGRDHTTVMHGTEKIADLIETDYALKQRIENLSTKIKEKS
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y383_PYRFU
Sequence: MKKVIHIGLPELSEEELIRVGEIGQKIIINYIFDHLAKSEVRDLEVTARINRGETLDLELEVYVEVPIFVKVDVESLIEEALDKAYEAIEDYLRRISNERGEKAQRTSEEP
What are the official names of this protein?
Uncharacterized protein PF0383.
What is the protein family that this protein belongs to?
Belongs to the UPF0440 family.
Protein: HPPK_STRP3
Sequence: MTIVYLSLGTNMGDRAAYLQKALEALADLPQTRLLAQSSIYETTAWGKTSQADFLNMAYQLDTQLTAADFLKETQAIEQSLGRVRHEKWGSRTIDIDILLFGEEVYDTKELKVPHPYMTERAFVLIPLLELQPDLKLPPNHKLLRDYLAALDQSDITLFSAQ
What is the function of this protein?
Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.
What are the official names of this protein?
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, PPPK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK.
What is the protein family that this protein belongs to?
Belongs to the HPPK family.
Protein: RS20_XANOP
Sequence: MANIKSAKKRAKQTIVRNERNTGQRSMLRTAVKKVIKALDANDAAGAEAAFAVAQPILDRFSARGLIHKNKAARHKSRLTARIKAIKAA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: MA1A2_HUMAN
Sequence: MTTPALLPLSGRRIPPLNLGPPSFPHHRATLRLSEKFILLLILSAFITLCFGAFFFLPDSSKHKRFDLGLEDVLIPHVDAGKGAKNPGVFLIHGPDEHRHREEEERLRNKIRADHEKALEEAKEKLRKSREEIRAEIQTEKNKVVQEMKIKENKPLPPVPIPNLVGIRGGDPEDNDIREKREKIKEMMKHAWDNYRTYGWGHNELRPIARKGHSPNIFGSSQMGATIVDALDTLYIMGLHDEFLDGQRWIEDNLDFSVNSEVSVFEVNIRFIGGLLAAYYLSGEEIFKIKAVQLAEKLLPAFNTPTGIPWAMVNLKSGVGRNWGWASAGSSILAEFGTLHMEFIHLSYLTGDLTYYKKVMHIRKLLQKMDRPNGLYPNYLNPRTGRWGQYHTSVGGLGDSFYEYLLKAWLMSDKTDHEARKMYDDAIEAIEKHLIKKSRGGLTFIGEWKNGHLEKKMGHLACFAGGMFALGADGSRADKAGHYLELGAEIARTCHESYDRTALKLGPESFKFDGAVEAVAVRQAEKYYILRPEVIETYWYLWRFTHDPRYRQWGWEAALAIEKYCRVNGGFSGVKDVYSSTPTHDDVQQSFFLAETLKYLYLLFSGDDLLPLDHWVFNTEAHPLPVLHLANTTLSGNPAVR
What is the function of this protein?
Involved in the maturation of Asn-linked oligosaccharides.  Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).
What are the official names of this protein?
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB, Mannosidase alpha class 1A member 2, Processing alpha-1,2-mannosidase IB, Alpha-1,2-mannosidase IB.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 47 family.
Protein: PTH_ALTMD
Sequence: MADIRLIVGLGNPGPEYENTRHNAGEWFLNQLADTYNAPLKPETKFFGKTARITIDGKDIRLLYPTTFMNKSGQAVAALANFYRIEPEQILVAFDELDLPPGVAKYKVGGSSSQNGVRDIVARMGNNKNFLRLRIGIGHPGHKSRVTGHVLGKPSAEEKTAIESAIDEAVRCTEILLKEDLKQAQNRLHSHKV
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDH_XANC8
Sequence: MKAPVRVAVTGAAGQIGYALLFRIASGEMLGKDQPVILQLLELSNEKAQAALKGVMMELEDCAFPLLAGMVGTDDAEVAFKDIDVALLVGARPRGPGMERKDLLLENAKIFTAQGAALNKVAKRDVKVLVVGNPANTNAYIAMKSAPDLNPKNFTAMLRLDHNRALSQLSLKLGKPVGGIEKLVVWGNHSPTMYPDYRFATSDGASIGDAINDQEWNAGTFIPTVGKRGAAIIEARGLSSAASAANAAIDHVRDWVLGSNGKWVTMGVPSDGSYGIPEGVIFGFPVTTENGQYTLVKDLPIDDFSQKYIDKTLAELEEERSGVSHLLG
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: RL362_ARTS2
Sequence: MKVRNSLRALKKIPGAQIVRRRGRTFVINKKNPRMKARQG
What are the official names of this protein?
50S ribosomal protein L36 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: HA19_CANLF
Sequence: MEVVMPRALLVLLSAALALTPTRAGSHSLRYFYTSVSRPGAGDPRFIAVGYVDDTQFVRFDSDAATGRMEPRAPWVEQEGPEYWDRQTRTIKETARTFRVDLDTLRGYYNQSEAGSHTRQTMYGCDLGPDGRLLRGYSQDAYDGADYIALNEDLRSWTAADTAAQITQRKWEAAGVAELQWRNYLETTCVEWLRRYLEMGKETLLRADPPSTRVTHHPVSDHEVTLRCWALGFYPAEITLTWQRDGEDQTQDTEVVDTRPAGDGTFQKWAAVVVPSGQEQRYTCHVQHEGLPEPITRRWEPSPLSTIVIVSIAALVLLVVAGVIGAVIWRKQRSGGKGPGYSHAARDDSAQGSDVSLTAPRV
What is the function of this protein?
Involved in the presentation of foreign antigens to the immune system.
What are the official names of this protein?
DLA class I histocompatibility antigen, A9/A9 alpha chain.
What is the protein family that this protein belongs to?
Belongs to the MHC class I family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: MDTC_SALPA
Sequence: MRFFALFIYRPVATILIAAAITLCGILGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEMTSSSSLGSTRIILEFNFDRDINGAARDVQAAINAAQSLLPGGMPSRPTYRKANPSDAPIMILTLTSESWSQGKLYDFASTQLAQTIAQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDEVREAIDSANVRRPQGAIEDSVHRWQIQTNDELKTAAEYQPLIIHYNNGAAVRLGDVASVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDGIRAKLPELRAMIPAAIDLQIAQDRSPTIRASLQEVEETLAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENIARHLEAGMKPLQAALQGTREVGFTVISMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLVVSLTLTPMMCGWMLKSSKPRTQPRKRGVGRLLVALQQGYGTSLKWVLNHTRLVGVVFLGTVALNIWLYIAIPKTFFPEQDTGVLMGGIQADQSISFQAMRGKLQDFMKIIRDDPAVNNVTGFTGGSRVNSGMMFITLKPRGERKETAQQIIDRLRVKLAKEPGARLFLMAVQDIRVGGRQANASYQYTLLSDSLPALREWEPKIRKALSALPQLADVNSDQQDNGAEMNLIYDRDTMSRLGIDVQAANSLLNNTFGQRQISTIYQPMNQYKVVMEVDPRYTQDISALEKMFVINRDGKAIPLSYFAQWRPANAPLSVNHQGLSAASTIAFNLPTGTSLSQATEAINRTMTQLGVPSTVRGSFSGTAQVFQQTMNSQLILIVAAIATVYIVLEILYESYVHPLTILSTLPSASVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRSGGLTPEQAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLRFSRKNSKPVVEI
What are the official names of this protein?
Multidrug resistance protein MdtC, Multidrug transporter MdtC.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RIBB_SHEB2
Sequence: MNQSLLAPFGTAIERVEAGLNALRQGQGVLVVDDEDRENEGDLIFAAETLTNAQMAMLIRECSGIVCLCLPDEKVKALELPAMVEHNSSQYGTAFTVSIEATVGVTTGVSAADRVTTIKAAIADNAKPSDLARPGHVYPLRAQPGGVLTRRGHTEGTIDLVQLAGLKPAGVLCEVTNPDGTMARLPEIIAFGALHNMPVLTIEDIVVYRKSLLAKVG
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: PHS_AGRRK
Sequence: MKYEKLEPAAIDETVAGLVGWTLAADRLSISKSYKFRNFVEAFGFMTEAALTAEKLNHHPEWFNVYSRVDVKLTTHDANGLTDHDVKLAKAMEKAAARRAD
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: MUTS_ECOHS
Sequence: MSAIENFDAHTPMMQQYLRLKAQHPEILLFYRMGDFYELFYDDAKRASQLLDISLTKRGASAGEPIPMAGIPYHAVENYLAKLVNQGESVAICEQIGDPATSKGPVERKVVRIVTPGTISDEALLQERQDNLLAAIWQDSKGFGYATLDISSGRFRLSEPADRETMAAELQRTNPAELLYAEDFAEMSLIEGRRGLRRRPLWEFEIDTARQQLNLQFGTRDLVGFGVENAPRGLCAAGCLLQYAKDTQRTTLPHIRSITMEREQDSIIMDAATRRNLEITQNLAGGAENTLASVLDCTVTPMGSRMLKRWLHMPVRDTRVLLERQQTIGALQDFTAGLQPVLRQVGDLERILARLALRTARPRDLARMRHAFQQLPELRAQLETVDSAPVQALREKMGEFAELRDLLERAIIDTPPVLVRDGGVIASGYNEELDEWRALADGATDYLERLEVRERERTGLDTLKVGFNAVHGYYIQISRGQSHLAPINYMRRQTLKNAERYIIPELKEYEDKVLTSKGKALALEKQLYEELFDLLLPHLEALQQSASALAELDVLVNLAERAYTLNYTCPTFIDKPGIRITEGRHPVVEQVLNEPFIANPLNLSPQRRMLIITGPNMGGKSTYMRQTALIALMAYIGSYVPAQKVEIGPIDRIFTRVGAADDLASGRSTFMVEMTETANILHNATEYSLVLMDEIGRGTSTYDGLSLAWACAENLANKIKALTLFATHYFELTQLPEKMEGVANVHLDALEHGDTIAFMHSVQDGAASKSYGLAVAALAGVPKEVIKRARQKLRELESISPNAAATQVDGTQMSLLSVPEETSPAVEALENLDPDSLTPRQALEWIYRLKSLV
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: COX2_ATRSP
Sequence: MAHPSQLGFQDAASPVMEELLHFHDHALMIVFLISTLVLYIIVAMVSTKLTNKHILDSQEVEIVWTILPAVI
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TRPA_MYCUA
Sequence: MTVEQREASRLGPLFDSCRAENRAALIGYLPTGYPDVNTSVRAMTELVESGCDIVEVGVPYSDPGMDGPTIQRATEAALSGGVRVRDALTAVESISKAGGRAVVMTYWNPVLRYGGDAFARDLAAAGGHGLITPDLIPDEAQQWLAASDAHGLDRIFLVAPSSTPERLANTVAASRGFVYAASTMGVTGARDAVSNAAPDLVARVKAVSDIPVGVGLGVRSREQAAEIGRYADGVIVGSALVSALGDGLPSLRSLTEELAAGVRQRKSP
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: TLPH_ORYSJ
Sequence: MATPLLLVVNAILIMAITACGGGGGNGGIQLIMVNNCGESVWPGLLGTAGHPTPQSGGFHLGAGEEAALEVPAGWSGRVWPRRGCSFDSRGRGSCATGDCGGVLRCNGAAGATPATVVEMTLGTSASAMHFYDVSLVDGFNAPVSMAAVGGGVGCGTAACGADVNVCCPSALEVRDREGRVAGCRSACRAMGGDRYCCTGDYASPSACRPTIFSHLFKAICPRAYSYAYDDATSLNRCHAKRYLITFCPPQPS
What are the official names of this protein?
Thaumatin-like protein.
What is the protein family that this protein belongs to?
Belongs to the thaumatin family.
Protein: Y1172_SHESW
Sequence: MTVITTLGLFIITAIAEIVGCYLPYLWLKKGASAWVLLPAAISLALFAWLLTLHPTAAGRVYAAYGGVYVTIAIVWLWGVDGIQPHRWDLAGVVLMLAGMAVIMFAPR
What are the official names of this protein?
UPF0060 membrane protein Sputw3181_1172.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CASK_CAPCA
Sequence: VALINNQLLPYPYYAKPGAVRSPAQILQWQVLPNTVPAKSCQAQPTTMARHPHPRLSFMAIPPKKNQDKTDIPTTNTIATVESTITPTTEAIEDTVAALEASSEVTESAPETNTDQVTSTVVE
What is the function of this protein?
Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk.
What are the official names of this protein?
Kappa-casein.
What is the protein family that this protein belongs to?
Belongs to the kappa-casein family.
What are the subcellular locations of this protein?
Secreted.
Protein: APTX_YEAST
Sequence: MSWRYALKNYVTSPETVNDDTVTYFDDKVSIIRDSFPKSECHLLILPRTMQLSRSHPTKVIDAKFKNEFESYVNSAIDHIFRHFQEKFRIKKSDDDKDPCWDDILKDKNKFVRNFVQVGIHSVPSMANLHIHVISKDFHSVRLKNKKHYNSFNTGFFISWDDLPLNGKNLGTDKEIETTYLKEHDLLCCYCQRNFSNKFSLLKKHLELEFNSHFELK
What is the function of this protein?
DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair.  Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species.  Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined (PubMed:16964241, PubMed:24362567).  Likewise, catalyzes the release of 3'-linked guanosine (DNAppG) and inosine (DNAppI) from DNA, but has higher specific activity with 5'-linked adenosine (AppDNA) (By similarity).
What are the official names of this protein?
Aprataxin-like protein, Hit family protein 3.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: RL3_MYCSS
Sequence: MARKGILGTKLGMTQVFDENNKVVPVTVVKAGPNVVTRIRTPERDGYSAVQIAYGEISPRKVNKPVTGQFAAAGVNPRRHLAELRLDDESAAADYEVGQELTAEVFSDGAYVDVTGTSKGKGFAGTMKRHGFKGQGAAHGAQAVHRRPGSIGGCATPGRVFKGTRMSGRMGSDRVTTQNLVVHKVDAANGVLLIKGAIPGRNGGLVMVRSAIKRGEK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: HEMH_BRUSI
Sequence: MSGTDKVRVNVSQTAQTPLHTSAKLPKVGVLLVNLGTPDGTSYGPMRRYLAEFLSDRRVIEWSRLIWYPILYGIVLNTRPRRSGRLYDRIWNHENNESPLRTYTRAQGEKLAKALSDQPNVVVDWAMRYGQPSIESITDRLLQQGCERIVIFPLYPQYSATTTATVNDKFFEALMKKRFMPAIRTVPSYEAEPVYIDALARSVEKHLATLSFKPEVILTSYHGIPKSYSDKGDPYRQQCLETTRLLRERLGLGEDEMRATFQSRFGPEEWLQPYTDETVKELAKNGVKSVAVLNPGFVADCLETVDEIGNEAAEEFLENGGENFSHIPCLNDSEEGMKVIETLVRRELLGWV
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE1_PSEAE
Sequence: MKISRQAYADMFGPTVGDRVRLADTDLWIEVERDFTVYGEEVKFGGGKVIRDGMGQSQLGAAQVVDTVITNALILDHWGVVKADVGLKDGRIQAIGKAGNPDIQPGVNIAIGAGTEVIAGEGMILTAGGIDTHIHFICPQQIEEALMSGVTTMIGGGTGPAAGTNATTCTSGPWHMARMLQAADAFPMNIGFTGKGNASLPLPLEEQVLAGAIGLKLHEDWGSTPAAIDNCLEVAERHDIQVAIHTDTLNESGFVETTLGAFKGRTIHTYHTEGAGGGHAPDIIKACGFANVLPSSTNPTRPFTRNTIDEHLDMLMVCHHLDPAIAEDVAFAESRIRRETIAAEDILHDLGAFSMISSDSQAMGRVGEVITRTWQTADKMKRQRGRLDGDGARNDNFRARRYIAKYTINPAITHGISHEVGSVEAGKWADLVLWRPAFFGVKPSLILKGGAIAASLMGDINGSIPTPQPVHYRPMFASYAGSRHATSLTFVSQAAFAAGVPQQLGLRKAIGVVSGCRGVQKTDLIHNGYLPTIEVDAQNYQVRADGQLLWCEPADVLPMAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBN_ECOL6
Sequence: MELIFLGTSAGVPTRTRNVTAILLNLQHPTQSGLWLFDCGEGTQHQLLHTAFNPGKLDKIFISHLHGDHLFGLPGLLCSRSMSGIIQPLTIYGPHGIREFVETALRISGSWTDYPLEIVEIGAGEIFDDGLRKVTAYPMEHPLECYGYRIEEHDKPGALNAQALKAAGVPPGPLFQELKAGKTIMLDDGRQINGADYLAVPVPGKALAIFGDTGPCDAALELAKGVDVMVHEATLDMAMEAKANSRGHSSTRQAAALAREAGVGKLIITHVSSRYDDKGCQHLLRECRSIFPATELANDFAVFSI
What is the function of this protein?
Zinc phosphodiesterase, which has both exoribonuclease and endoribonuclease activities.
What are the official names of this protein?
Ribonuclease BN, RNase BN, Ribonuclease Z homolog, RNase Z homolog.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family. RNase BN subfamily.