PharMolix/UniProtQA huggingface dataset:
Protein: SYK_METKA
Sequence: MTKEHWSEVKAREVTEHCRKHADELPDEIVVASGASTSGRLHVGNARDVLTADAVARVLRERYHEDVRVVWISDDVDPLRRIPRDLDGRLSEDYLGVPYKAIPVGDEPYSDRWARNFVEELREFGAEVEWISSAELYTDNGFVKLVREVVNDYYGGGGRLASVLERFGLEDARVYMPVCEECGRIATTRVVDVDGWRIEYVCEGRHEIGDAVLEGCGHRGELDLRKPIEVNGFEIPPGKLGWKIEWPTRWVYLGVACEPFGKDHYVAGGSYEVGSAIAEEFFGFPAPVPVPYEWITLDGKAMSSSKGHYVTLSDWGEVCHREVLRYLVLRGKPLKHLDLDLRFGLLQAVDDYDELEKRYFAGEADERERRIYELSRVDEIPEECPPHVPFRFCAVVAQVVGIEDDVSEEEFERALEIFRRTGHLEAEPEGFGREWLRERLEKASRWVDRYAPEEARFRVREEPEPVELSDKEREFLEDLVRRLESETTKEDPETLQRTVFEAARTAGLRPADAFRVFYNVVVGKDRGPRAGTLIAAVGVDRISRLIRGCLEASED
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_STAAC
Sequence: MEAKAVARTIRIAPRKVRLVLDLIRGKNAAEAIAILKLTNKASSPVIEKVLMSALANAEHNYDMNTDELVVKEAYANEGPTLKRFRPRAQGRASAINKRTSHITIVVSDGKEEAKEA
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: YBX2A_XENLA
Sequence: MSEAEAQEPEPVPQPESEPEIQKPGIAAARNQANKKVLATQVQGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKFLRSVGDGETVEFDVVEGEKGAEAANVTGPGGVPVKGSRFAPNRRRFRRRFYRPRADTAGESGGEGVSPEQMSEGERGEETSPQQRPQRRRPPPFFYRRRFRRGPRPNNQQNQGAEVTEQSENKDPVAPTSEALASGDDPQRPPPRRFRQRFRRPFRPRPAPQQTPEGGDGETKAESGEDPRPEPQRQRNRPYVQRRRRQGATQVAATAQGEGKAEPTQHPASEEGTPSDSPTDDGAPVQSSAPDPGIADTPAPE
What is the function of this protein?
Has a dual function in oocytes: as a DNA-binding protein, binds to the Y-box sequence (CTGATTGGCCAA) in the promoters of target genes to stimulate transcription.  May also function at CCAAT-containing promoters that lack the consensus Y-box sequence.  Also binds mRNA to promote accumulation of the transcripts it contributes to produce.
What are the official names of this protein?
Y-box-binding protein 2-A, Cytoplasmic RNA-binding protein p56, Frog Y-box protein 2, FRG Y2, Frog Y-box protein 2-A, FRGY2a, Messenger ribonucleoprotein particle 4, mRNP4.
What are the subcellular locations of this protein?
Cytoplasm. Note=Either free or associated with ribonucleoprotein particles.
Protein: TRMA_HYDCU
Sequence: MLCQTYPETYAEQFAEKTHRLEQLLGDLPNFDAFASEPEHYRARAEFRVWHEGDQTDYIMFDQQSKEKVAIHHCPMALESIATLMPKLMAHIVQTPVLRQKLFQVDFLATLSGEMLVTLIYRKSLQTKTETGVENDVAWVDAANALRCELPITHIIGRARKQKICLDKDYVIEKLQVDHQTFIYQQIENSFTQPNAEMAQNMLHWARKVAAKANPDQQNDLIELYCGNGHFSIALSDQFHRVLATEISKTSVASAQFNIEANKVDNVTVVKMAAEEISAALQGETFFRLKDIDLSAYAFNTIFVDPPRSGLDDLTRQMVTEFDYIIYISCNPETLAHDLEAIRQTHEVLETALFDQFPYTHHIESGVFLKRKPK
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: DUS21_MOUSE
Sequence: MTTASCIFPSQATQQDNIYGLSQITASLFISNSAVANDKLTLSNNHITTIINVSAEVVNTFFEDIQYVQVPVSDAPNSYLYDFFDPIADHIHGVEMRNGRTLLHCAAGVSRSATLCLAYLMKYHNMTLLDAHTWTKTCRPIIRPNNGFWEQLIHYEFKLFSRNTVRMIYSPIGLIPNIYEKEAYLMELM
What is the function of this protein?
Can dephosphorylate single and diphosphorylated synthetic MAPK peptides, with preference for the phosphotyrosine and diphosphorylated forms over phosphothreonine.
What are the official names of this protein?
Dual specificity phosphatase 21.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: GLSA_CLOBK
Sequence: MNRLLKTIIENNRKWISEGKVASYIPELSKMDKNLLGISVCTLGGEEYWEGDAEVKFTIQSISKIVTLMLAIIDNGEDYVFSKVGMEPTETAFNSIVNLEAKESHKPINPMINAGAIVVASMVAGKDSDEKFDRILKFTRKISGNNDIDINLNVYESEKETGHRNRALAYFMKSTGALKGNVEEILDVYFKQCSIEITCKDLARIGVMLANDGVSPYTGDRIVPRHVARIVKTIMVTCGMYDASGNFAVHIGIPAKSGVGGGIIACAPRRMGIGVLGTALDEKGNSIAGTKILEELSKQLDLSIF
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: RS5_HELPJ
Sequence: MEEINREEFQEVVVNIGRVTKVVKGGRRFRFNALVVVGNKNGLVGFGLGKAKEVPDAIKKAVDDAFKNLIHVTIKGTTIAHDIEHKYNASRILLKPASEGTGVIAGGSTRPIVELAGIKDILTKSLGSNNPYNVVRATFDALAKIKA
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: YCFP_ECOLU
Sequence: MIIYLHGFDSNSPGNHEKVLQLQFIDPDVRLISYSTRHPKHDMQHLLKEVDKMLQLNVDERPLICGVGLGGYWAERIGFLCDIRQVIFNPNLFPYENMEGKIDRPEEYADIATKCVTNFREKNRDRCLVILSRNDEALNSQRTSEELHHYYEIVWDEEQTHKFKNISPHLQRIKAFKTLG
What are the official names of this protein?
UPF0227 protein YcfP.
What is the protein family that this protein belongs to?
Belongs to the UPF0227 family.
Protein: Y1691_METAC
Sequence: MISIAFKHYGFYSPSSNEILETIQMVRMEHLDIRTVTMGISLRDCSHPDPEVFNENIYEKITSRAKELIRTTNEIQSLYGIPIINRRISVTPISIAAESCRSQDFVSVAKTMDEAAKEAGVDFIGGFSALVHKGETRGDLKLINSIPEALASTEKVCSSVNVATTKAGINMDAVGLMGKVIKKTAELTAERDGIGCAKLVVFANAPEDNPFMAGAFHGIGEPECVINVGVSGPGAVNTAVCELENPNLTEISETIKKTAFKITRMGEMVGKEVSRRLGVEFGILDLSLAPTPAIGDSVAAILEAMGLERCGTHGTTAALALLNDAVKKGGAMASSSVGGLSGAFIPVSEDAGMIEAVKAGSLTLEKLEAMTSVCSVGLDMIAVPGDTSAATLSAIIADEMAVGVINKKTTAVRIIPAPGKAVGDSVEFGGLLGSAPIMPVSSFSSETFVNRGGRIPAPIQSLTN
What are the official names of this protein?
UPF0210 protein MA_1691.
What is the protein family that this protein belongs to?
Belongs to the UPF0210 family.
Protein: TPSD3_ABIGR
Sequence: MALVSTAPLASKSCLHKSLISSTHELKALSRTIPALGMSRRGKSITPSISMSSTTVVTDDGVRRRMGDFHSNLWDDDVIQSLPTAYEEKSYLERAEKLIGEVKNMFNSMSLEDGELMSPLNDLIQRLWIVDSLERLGIHRHFKDEIKSALDYVYSYWGENGIGCGRESVVTDLNSTALGLRTLRLHGYPVSSDVFKAFKGQNGQFSCSENIQTDEEIRGVLNLFRASLIAFPGEKIMDEAEIFSTKYLKEALQKIPVSSLSREIGDVLEYGWHTYLPRLEARNYIQVFGQDTENTKSYVKSKKLLELAKLEFNIFQSLQKRELESLVRWWKESGFPEMTFCRHRHVEYYTLASCIAFEPQHSGFRLGFAKTCHLITVLDDMYDTFGTVDELELFTATMKRWDPSSIDCLPEYMKGVYIAVYDTVNEMAREAEEAQGRDTLTYAREAWEAYIDSYMQEARWIATGYLPSFDEYYENGKVSCGHRISALQPILTMDIPFPDHILKEVDFPSKLNDLACAILRLRGDTRCYKADRARGEEASSISCYMKDNPGVSEEDALDHINAMISDVIKGLNWELLKPDINVPISAKKHAFDIARAFHYGYKYRDGYSVANVETKSLVTRTLLESVPL
What is the function of this protein?
Involved in defensive oleoresin formation in conifers in response to insect attack or other injury.  Involved in monoterpene (C10) olefins biosynthesis.  A mixture of alpha- and beta-pinene is produced by this enzyme.
What are the official names of this protein?
Pinene synthase, chloroplastic, (-)-(1S,5S)-pinene synthase, Agg-pin1, Beta-geraniolene synthase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsd subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: AROD_STAAM
Sequence: MTHVEVVATIAPQLSIEETLIQKINHRIDAIDVLELRIDQIENVTVDQVAEMITKLKVMQDSFKLLVTYRTKLQGGYGQFINDLYLNLISDLANINGIDMIDIEWQADIDIEKHQRIIKHLQQYNKEVVISHHNFESTPPLDELQFIFFKMQKFNPEYVKLAVMPHNKNDVLNLLQAMSTFSDTMDCKVVGISMSKLGLISRTAQGVFGGALTYGCIGEPQAPGQIDVTDLKAQVTLY
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: NDHH_SACOF
Sequence: MSLSLKRKDLMIVNMGPQHPSMHGVLRLIVTLDGEDVIDCEPILGYLHRGMEKIAENRSIIQYLPYVTRWDYLATMFTEAITVNAPEFLENIQIPQRASYIRVIMLELSRIASHLLWLGPFMADLGAQTPFFYIFRERELIYDLFEAATGMRMMHNYFRIGGVAADLPYGWMDKCLDFCDYFLQGVVEYQQLITQNPIFLERVEGVGFISGEEAVNWGLSGPMLRASGIQWDLRKIDPYESYNQFDWKVQWQKEGDSLARYLVRVGEMRESIKIIQQAVEKIPGGPYENLEARRFKKAKNPEWNDFEYRFLGKKPSPNFELSKQELYVRVEAPKGELGIYLVGDDSLFPWRWKIRPPGFINLQILPQLVKKMKLADIMTILGSIDIIMGEVDR
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit H, chloroplastic, NAD(P)H dehydrogenase subunit H, NADH-plastoquinone oxidoreductase 49 kDa subunit, NADH-plastoquinone oxidoreductase subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: RPOA_YERPA
Sequence: MQGSVTEFLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTLNKSGIGPVTAADITHDGDVEIVKPQHVICHLTDENASINMRIKVQRGRGYVPASARIHSEEDERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETNGTIDPEEAIRRAATILAEQLEAFVDLRDVRQPEVKEEKPEFDPILLRPVDDLELTVRSANCLKAEAIHYIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLENWPPASIADE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: RPOA_RECAM
Sequence: MVHKTPSFRPIIHVLKHDFNSIQVLIGPLEKNFSGSFANLLRKIIFRYTSGVSIIGLKINGIDSLHSYSLIPGVKEDVLNVLNNLKHLLIQIDDYDYKPILLTIQKKGPYIIKSKDIICPSNIKILNDDLYICTLENDSQIDLTLIGDIGCGYVLSTYFGNRKSIVYSDTNFCPIKHVSYYVRSYTTYEELIFYIKTNGTCNPLFVMKNAFSFLKDKINITF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, mitochondrial, RNA polymerase subunit alpha, Transcriptase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NU1C_CHLAT
Sequence: MLLIIDLQTAFINWFVGLGVSKDISAALWIPLPILVVIVGATIGVLVIVWLERKISAGVQQRIGPEFAGPLGVLQPLADGLKLVFKEDIIPSKADIWLFTLGPALVVIPVFLAYLVVPFGHDLVVADISLGVFFWIAISSIAPIGLLMSGYGSNNKYSFLGGLRAAAQAISYEIPLSLCVLAICLLSNSLSTVEIVEQQSAYGILGWNVWRQPIGFVSFLIAALAECERLPFDLPEAEEELVAGYQTEYSGMKFGLFYVGSYVNLLLSSLFATILYLGGWTSPITFSIPFQTSEIEIFAAFLGIGMTLLKAYLFIFLSILTRWTLPRVRIDQLLDLGWKFLLPISLGNLLLTASLRLAFY
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic, NAD(P)H dehydrogenase subunit 1, NDH subunit 1, NADH-plastoquinone oxidoreductase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RR7_MANES
Sequence: MSRRGTAEEKTAKSDPIYRNRLVNMLVNRILKHGKKSLAYQIIYRAMKKIQQKTETNPLSVLRQAIRGVTPDIAVKARRVGGSTHQVPIEIGSTQGKALAIRWLLGASRKRPGRNMAFKLSSELVDAAKGSGDAIRKKEETHRMAEANRAFAHFR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SBCC_ECOLI
Sequence: MKILSLRLKNLNSLKGEWKIDFTREPFASNGLFAITGPTGAGKTTLLDAICLALYHETPRLSNVSQSQNDLMTRDTAECLAEVEFEVKGEAYRAFWSQNRARNQPDGNLQVPRVELARCADGKILADKVKDKLELTATLTGLDYGRFTRSMLLSQGQFAAFLNAKPKERAELLEELTGTEIYGQISAMVFEQHKSARTELEKLQAQASGVTLLTPEQVQSLTASLQVLTDEEKQLITAQQQEQQSLNWLTRQDELQQEASRRQQALQQALAEEEKAQPQLAALSLAQPARNLRPHWERIAEHSAALAHIRQQIEEVNTRLQSTMALRASIRHHAAKQSAELQQQQQSLNTWLQEHDRFRQWNNEPAGWRAQFSQQTSDREHLRQWQQQLTHAEQKLNALAAITLTLTADEVATALAQHAEQRPLRQHLVALHGQIVPQQKRLAQLQVAIQNVTQEQTQRNAALNEMRQRYKEKTQQLADVKTICEQEARIKTLEAQRAQLQAGQPCPLCGSTSHPAVEAYQALEPGVNQSRLLALENEVKKLGEEGATLRGQLDAITKQLQRDENEAQSLRQDEQALTQQWQAVTASLNITLQPLDDIQPWLDAQDEHERQLRLLSQRHELQGQIAAHNQQIIQYQQQIEQRQQLLLTTLTGYALTLPQEDEEESWLATRQQEAQSWQQRQNELTALQNRIQQLTPILETLPQSDELPHCEETVVLENWRQVHEQCLALHSQQQTLQQQDVLAAQSLQKAQAQFDTALQASVFDDQQAFLAALMDEQTLTQLEQLKQNLENQRRQAQTLVTQTAETLAQHQQHRPDDGLALTVTVEQIQQELAQTHQKLRENTTSQGEIRQQLKQDADNRQQQQTLMQQIAQMTQQVEDWGYLNSLIGSKEGDKFRKFAQGLTLDNLVHLANQQLTRLHGRYLLQRKASEALEVEVVDTWQADAVRDTRTLSGGESFLVSLALALALSDLVSHKTRIDSLFLDEGFGTLDSETLDTALDALDALNASGKTIGVISHVEAMKERIPVQIKVKKINGLGYSKLESTFAVK
What is the function of this protein?
SbcCD cleaves DNA hairpin structures.  These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions.  The complex acts as a 3'->5' double strand exonuclease that can open hairpins.  It also has a 5' single-strand endonuclease activity.
What are the official names of this protein?
Nuclease SbcCD subunit C.
What is the protein family that this protein belongs to?
Belongs to the SMC family. SbcC subfamily.
Protein: GET1_COCP7
Sequence: MPSLLIIVLIIHVVTYLINTIGANTIDSLLWLLYLKLPNQTSQTADEQRRLKREVMQLKREMNATSSQDEFAKWAKLRRRHDKTMEEYEAKNKALGKHKSSFDLAVKSVRFFSTTGLKLFLQFWFSKTPIFELPRGWIPWQVEWVLSFPRAPLGTVSIQIWGGVCATVVSLAGDAIGVVNVYLTSKAPKQKEPATSGENSARPMAIKKEL
What is the function of this protein?
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.
What are the official names of this protein?
Protein GET1, Guided entry of tail-anchored proteins 1.
What is the protein family that this protein belongs to?
Belongs to the WRB/GET1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: UVRB_SYMTH
Sequence: MKPFKVVAPFEPTGDQPQAIERLSEGVRRGAREQILLGATGTGKTFTIAKVIEQVQKPTLVLAHNKILAAQLCSEFQQFFPENAVEYFVSYYDYYQPEAYIPTTDTYIEKDALINDEIDKLRHSATMALFERRDVIIVASVSCIYGLGSPEDYRDLAVSLRVGNQVDRDYILRRLVDIQYERNDHNFVRNKFRVRGDVVEIFPAGATDRAIRCEWWGDEIERISEFDPLTGEITGTMTHVAIYPASHYVVADEKREQALRSIEEELEERLKELRAQGKLLEAQRLEQRTRNDLEMIREIGFCSGIENYSRHLTGRKPGEPPYTLLDFFPDDWLLVIDESHVTIPQVAAMYNGDRSRKETLIEYGFRLPSAADNRPLKFAEFEERINQVIYVSATPGPYELERVPPSLVVEQIVRPTGLLDPEVEVRPTKGQIDDLYAEIRARVKKNQRVLVTTLTKRMAEDLTEYLKELGVKVRYMHSDVETIERMQIVRDLRLGVFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRAERSLIQTIGRAARNAEGKVIMYADRITQSMQKAINETNRRRAIQEAYNRKHGIVPKTIVKPVRDVIQAVKPVAEAGPANILDTPPHEIPKVVAKLRKEMMQAAKDLDFERAAEIRDIIFELEKKKRGA
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPK_DECAR
Sequence: MQDRSDQFVLALDQGTTSTRAILFGRKGDIHGVAQQEITQHYPQPGWVEHDAEEIWQAQLAVARAALRDNGILAKQIVAVGMTNQRETTVLWDRSSGEPLHRAIVWQDRRTAGLCDELTTAGHAGLFRERTGLVLDAYFSGTKLKWLLDHIPGARSRAERGELAFGTIDSWLTWKLSGGRAHVTDPSNASRTLLFDIHRCCWDEELLALLDIPMALLPRIVDSSGEIATIAAEWLGAEIPLSGIAGDQQAATFGQVCLQHGMAKNTYGTGCFLLMNTGQAPMASCHRLLTTIGWQRQGKTTYLLEGSVFMGGATVQWLRDGLGLISSADQIESLAASVADNGGVYLVPAHTGLGAPYWDPFARGALFGMTRGTTRAHIARAALEAIAFQSADVLQAMEKDAGQSLSELRVDGGAARNDLLMQFQADLLGVPVVRPQVTETTALGAAYLAGLAVGFWQDEAELTALWRADRRFEPSMAEDRRSALFADWHRAVERSLHWANAT
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: PUR6_SCHOC
Sequence: MDNKIVGILGGGQLGRMIVEAANRLNIKTVVLDVPNSPAKQINSNEHVDGSFTDLKSIIQLAEKCDILTVEIEHVDVEALKYVKEKFGVEIYPLPDTIKLIQDKYLQKEHLIQHGISVTESVAVPSNDEQSLIEIGNKFNYPFMLKSRTLAYDGRGNYVVKTKESIPEALEFLKDRPLYAEKWCPFNKELAVMVVRSIEGEVFAYPTVETIHKNNICHVVYAPARVSDSIAVKASVLAKNAVKSFPGCGIFGVEMFLLPNNEILINEIAPRPHNSGHYTIDACVTSQFEAHVRAVVGLPMPKNFTSLSTTTTNAIMLNVLGDEESNKELEICRRALETPNASVYLYGKSTRPNRKMGHINIVSSSMEDCESRLDYIIGKSSKIPENLIPKEKPLVSIIMGSDSDLPVMSVGANILKRFGVPFELTIVSAHRTPHRMTQYAIEAPKRGLKVIIAGAGGAAHLPGMVAAMTPLPVIGVPVKGSTLDGVDSLHSIVQMPRGIPVATVAINNSTNAALLAVRILGAYDYKWLNEMNQYMNNMENEVLAKAERLEEVGYEKY
What are the official names of this protein?
Phosphoribosylaminoimidazole carboxylase, AIR carboxylase, AIRC.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily.
Protein: TILS_FRATM
Sequence: MSISKSLVLNEIKKFSPSHIIIGYSGGVDSSVLLNISKELDIPLIAIYINHNLHRDSLKWQIHCQQTCQKYNLQFISHSLDKVPKGESFEAWASKQRMAFFQKIMQQYSKPLLLLGHHQDDQAETFLIQAIRGSGLAGLAGIPHYKELHHGGVLRPLLKYSKIEIEGFAKLNNISYIYDDSNEDIKYRRNLIRNQIIPILQQVNPNISQTLSRSANICAESNNILQKLLTERLQSISQDTNLIISELIKLDDDIQKNLLHLWFKQNTQQSLKSKQIKELHLAVNNPSTGWQIDISNYYQIHIQYNQLIIKYPTTINDISKKDIISWLSKNLNEEIDLTKIVIRDRKPDDKCKYRGRNKPNKLKILFQELQIPTTERSKAKIILKDQQIIAVYPFFICG
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_ECO5E
Sequence: MAKLTKRMRVIREKVDATKQYDINEAIALLKELATAKFVESVDVAVNLGIDARKSDQNVRGATVLPHGTGRSVRVAVFTQGANAEAAKAAGAELVGMEDLADQIKKGEMNFDVVIASPDAMRVVGQLGQVLGPRGLMPNPKVGTVTPNVAEAVKNAKAGQVRYRNDKNGIIHTTIGKVDFDADKLKENLEALLVALKKAKPTQAKGVYIKKVSISTTMGAGVAVDQAGLSASVN
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: ALR2_SALTY
Sequence: MTRPIQASLDLQVMKQNLAIVRRAAPEARVWSVVKANAYGHGIERVWSALGATDGFAMLNLEEAITLRERGWKGPILMLEGFFHAQDLEAYDTYRLTTCIHSNWQLKALQNARLNAPLDIYVKVNSGMNRLGFQPERAQTVWQQLRAMRNVGEMTLMSHFAQADHPEGIGEAMRRIALATEGLQCAYSLSNSAATLWHPQAHYDWVRPGIILYGASPSGQWRDIADTGLKPVMTLSSEIIGVQTLSAGERVGYGGGYSVTQEQRIGIVAAGYADGYPRHAPTGTPVLVDGIRTRTVGTVSMDMLAVDLTPCPQAGIGTPVELWGKEIKVDDVASAAGTLGYELLCAVAPRVPFVTT
What is the function of this protein?
Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA.
What are the official names of this protein?
Alanine racemase, catabolic.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: RLMF_ALIF1
Sequence: MTNTKSNVTKKSLHPRNKHTGNYDFPALIKACAELKPFVETNQYGNESINFSDPQAVKALNKALLAHFYNVPFWDIPQGYLCPPIPGRADYIHNIADLLAITNEGTIPTGKKVKGLDVGVGANCVYLIIGNREYQWSFVGSDIDPQSIKMASFIANNNPSLKGIECRLQKNEENIFKGIIKPTEFFDFTMCNPPFHASEAEATAGTERKQKNLAANKAKKGHAFQEMQNAKALNFGGQKAELWCEGGELAFILKMAQQSREFSLQVQWFTTLISKKENVAELYKELEKIGVKTIKTIEMAQGQKISRFVAWTYQANVNL
What is the function of this protein?
Specifically methylates the adenine in position 1618 of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase F, 23S rRNA mA1618 methyltransferase, rRNA adenine N-6-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL16/RlmF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRRS6_ARATH
Sequence: MTRIIDVSLFCFFLFSLGAMSQPSQNLTDCNQFPDTYQSNRNTVLSTLRNHSSLGSYYFNATAGLSPNTVYGMFLCIGNISKTSCSNCVHSATLEMDKSCESHDTSFMFSDECMVRYSDNSFFSLVEDSPATFSYSQNDSLSYPQFYNQTLPGKLDELILKAPSSFSSPVPYFVEDKEHVTQVEGSYDLEAMAQCSPDLDPSSCTVCLGLVVEKFSECCSQSRWARIHFPKCLLRYDISALQPNLTSLGVTTKGDDIFGRTFIAIMIGLLMGL
What are the official names of this protein?
Probable cysteine-rich repeat secretory protein 6.
What is the protein family that this protein belongs to?
Belongs to the cysteine-rich repeat secretory protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPD_XANP2
Sequence: MAAQGARHGLQVRERCGVADTIVSGMAGRYATALFELATEAGAVDSVKADLDRLSALIAESADLARLVKSPVFSAEEQLKAISAVLDQAGISGLAGNFVRRVAQNRRLFALPRMVADYASLVAAMRGETTAQVTVPAPLSDAHFFALKDALAQQTGKDVILDVTVDPSILGGLIVKLGSRMVDASLKTKLNSIRHAMKEVR
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.