PharMolix/UniProtQA huggingface dataset:
Protein: RL24_SALPC
Sequence: MAAKIRRDDEVIVLTGKDKGKRGKVKNVLSSGKVIVEGINLVKKHQKPVPALNQPGGIVEKEAAIQVSNVAIFNAATGKADRVGFRFEDGKKVRFFKSNSETIK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: SSRP_NITEU
Sequence: MSIVQNKKAFHDYFIEEKYEAGIVLEGWEVKAIRAGRAQLKEAYILIRKGELFLIGSHISPLATASTHVNPDPVKTRKLLLHASQIRELIGKVERAGYTLIPLDMHYKSGRIKLEIGLARGKKQYDKRETEKRKEWERDKQRLLRIRRSSD
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: FUR_STAEQ
Sequence: MNTNDAIKVLKENGLKYTDKRKDMLDIFVKEDKYLNAKHIQQQMDKDYPGISFDTVYRNLHLFKDLGIIESTELDGEMKFRIACTNHHHHHFICENCGETKVIDFCPIEKIKSQLPNVNIHTHKLEVYGICEECQRKAN
What is the function of this protein?
Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
What are the official names of this protein?
Ferric uptake regulation protein, Ferric uptake regulator.
What is the protein family that this protein belongs to?
Belongs to the Fur family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACYP_MYCTO
Sequence: MSAPDVRLTAWVHGWVQGVGFRWWTRCRALELGLTGYAANHADGRVLVVAQGPRAACQKLLQLLQGDTTPGRVAKVVADWSQSTEQITGFSER
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: SCNNG_MOUSE
Sequence: MAPGEKIKAKIKKNLPVRGPQAPTIKDLMHWYCLNTNTHGCRRIVVSRGRLRRLLWIAFTLTAVALIIWQCALLVFSFYTVSVSIKVHFQKLDFPAVTICNINPYKYSAVSDLLTDLDSETKQALLSLYGVKDVLDSTPRKRREAGSMRSTWEGTPPRFLNLIPLLVFNENEKGKARDFFTGRKRKISGKIIHKASNVMHVHESKKLVGFQLCSNDTSDCATYTFSSGINAIQEWYKLHYMNIMAQVPLEKKINMSYSAEELLVTCFFDGMSCDARNFTLFHHPMYGNCYTFNNRENATILSTSMGGSEYGLQVILYINEDEYNPFLVSSTGAKVLVHQQNEYPFIEDVGTEIETAMSTSIGMHLTESFKLSEPYSQCTEDGSDVPVTNIYNAAYSLQICLYSCFQTKMVEKCGCAQYSQPLPPAANYCNYQQHPNWMYCYYQLYQAFVREELGCQSVCKQSCSFKEWTLTTSLAQWPSEASEKWLLNVLTWDQSQQINKKLNKTDLAKLLIFYKDLNQRSIMESPANSIEMLLSNFGGQLGLWMSCSVVCVIEIIEVFFIDFFSIIARRQWQKAKDWWARRRTPPSTETPSSQQGQDNPALDTDDDLPTFTSAMRLPPAPEAPVPGTPPPRYNTLRLDSAFSSQLTDTQLTNEF
What is the function of this protein?
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride.  Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells.  Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus.  Controls the reabsorption of sodium in kidney, colon, lung and sweat glands.  Also plays a role in taste perception.
What are the official names of this protein?
Amiloride-sensitive sodium channel subunit gamma, Epithelial Na(+) channel subunit gamma, Gamma-ENaC, Gamma-NaCH, Nonvoltage-gated sodium channel 1 subunit gamma, SCNEG.
What is the protein family that this protein belongs to?
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. SCNN1G subfamily.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Note=Apical membrane of epithelial cells.
Protein: ATPE_ATRBE
Sequence: MTLNLSVLTPNRIVWDSEVEEIVLSTNSGQIGILSNHAPIATAVDIGILRIRLNDQWLTMALMGGFARIGNNEITVLVNDAEKGSDIDPQEAQQTLEIAEANVKKAEGRRQKIEANLALRRARTRVEAINPIS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, chloroplastic, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: CYF_TRIV2
Sequence: MRNACTRARLTRTARAMVKTLFIAIASVTFFFTSDLALPQSAAAYPFWAQQTYPETPREPTGRIVCANCHLAAKPTEVEVPQSVLPDTVFKAVVKIPYDTSVQQVGADGSKVGLNVGAVLMLPEGFKIAPEDRIPEELKEEIGDVYFQPYGEDKDNIVIVGPLPGEQYQEIVFPVLSPNPANDKNIHFGKYSVHVGGNRGRGQVYPTGEKSNNNLYSAAATGTISKIAKQEGEDGSVKYLVDIKTESGEVVSDTIPAGPELIVSEGQAVKAGDALTNNPNVGGFGQLDAEIVLQDANRVGWLIAFVALVMLAQVMLVLKKKQVEKVQAAEMNF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome f family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: STK10_BOVIN
Sequence: MAFANFRRILRLSTFEKRKSREYEHVRRDLDPNEVWEIVGELGDGAFGKVYKAKNKETGALAAAKVIETNSEEELEDYIVEIEILATCDHPYIVKLLGAYYYDGKLWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALTFLHGKKIIHRDLKAGNVLMTLEGDIRLADFGVSAKNLKTLQKRDSFIGTPYWMAPEVVMCETMKDTPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLLSPSKWSAEFRDFLKTALDKNPETRPSAAQLLEHPFVSSVTSNKALRELVAEAKAEVMEEIEDGRDEGDEEDAVEAASPLENHTRDSSEVSQLSIDADKLLKESPFTPPPPSQPQDGANGPSEPPGHGALPATSPLDVAPGNENGQAVPVPLRKFRPVSMGARIQVSEEKQAADQGGDLSPAASRSQKASQSRPNSSALETLRSELTNGSLELPTPGAQSLSKRDSDCGSVSTSGSTDFGTSLSADMSVNKESGSLSIKDSRLHNKTLKRTRKFVVDGVEVSITTSKIISEDEKKDEEMRFLRRQELRELRLLQKEEHRNQTQLSSKHELQLEQMHKRFEQEINAKKKFFDIELENLERQQKQQVEKMEQDHAVRRREEAKRIRLEQERDYAKFQEQLKLMKKEVKNEVEKLPRQQRKESMKQKMEEHTQKKQLLDRDFLAKQKEDLELAMKRITADNRREICDKERECLTRKQELLRDREAALWEMEEHHLQERHQLVKQQLKDQYFLQRHELLRKHEKEREQMQRYNQRMIEQLKVRQQQEKARLPKIQRSEGKTRMAMYKKSLHINGGGSAAEQREKIKQFSQQEEKRQKAERLQQQQKHENQMRDMLAQCESNMSELQQLQNEKCHLLIEHETQKLKALDESHNQNLKEWRDKLRPRKKALEEDLNQKKREQEMFFKMNEESECANPTSPNKVTKFFPYSSADAA
What is the function of this protein?
Serine/threonine-protein kinase involved in regulation of lymphocyte migration.  Phosphorylates MSN, and possibly PLK1.  Involved in regulation of lymphocyte migration by mediating phosphorylation of ERM proteins such as MSN.  Acts as a negative regulator of MAP3K1/MEKK1.  May also act as a cell cycle regulator by acting as a polo kinase kinase: mediates phosphorylation of PLK1 in vitro; however such data require additional evidences in vivo (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase 10.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MURC_SHISS
Sequence: MNTQQLAKLRSIVPEMRRVRHIHFVGIGGAGMGGIAEVLANEGYQISGSDLAPNPVTQQLMNLGATIYFNHRPENVRDASVVVVSSAISADNPEIVAAHEARIPVIRRAEMLAELMRFRHGIAIAGTHGKTTTTAMVSSIYAEAGLDPTFVNGGLVKAAGVHARLGHGRYLIAEADESDASFLHLQPMVAIVTNIEADHMDTYQGDFENLKQTFINFLHNLPFYGRAVMCVDDPVIRELLPRVGRQTTTYGFSEDADVRVEDYQQIGPQGHFTLLRQDKEPMRVTLNAPGRHNALNAAAAVAVATEEGIDDEAILRALESFQGTGRRFDFLGEFPLEPVNGKSGTAMLVDDYGHHPTEVDATIKAARAGWPDKNLVMLFQPHRFTRTRDLYDDFANVLTQVDTLLMLEVYPAGEAPIPGADSRSLCRTIRGRGKIDPILVPDPAQVAEMLAPVLIGNDLILVQGAGNIGKIARSLAEIKLKPQTPEEEQHD
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAT_HV1MV
Sequence: MDPVDPEMPPWHHPGSKPQTPCNNCYCKRCCYHCYVCFTKKGLGISHGRKKRRRPAAAASYPDNKDPVPEQHTGRKQKRQEEQEKKVEKETGPSGQPCHQDSCNSCTRISGQ
What is the function of this protein?
Extracellular circulating Tat can be endocytosed by surrounding uninfected cells via the binding to several surface receptors such as CD26, CXCR4, heparan sulfate proteoglycans (HSPG) or LDLR.  Neurons are rarely infected, but they internalize Tat via their LDLR.  Through its interaction with nuclear HATs, Tat is potentially able to control the acetylation-dependent cellular gene expression.  Modulates the expression of many cellular genes involved in cell survival, proliferation or in coding for cytokines or cytokine receptors.  Tat plays a role in T-cell and neurons apoptosis.  Tat induced neurotoxicity and apoptosis probably contribute to neuroAIDS.  Circulating Tat also acts as a chemokine-like and/or growth factor-like molecule that binds to specific receptors on the surface of the cells, affecting many cellular pathways.  In the vascular system, Tat binds to ITGAV/ITGB3 and ITGA5/ITGB1 integrins dimers at the surface of endothelial cells and competes with bFGF for heparin-binding sites, leading to an excess of soluble bFGF.
What are the official names of this protein?
Protein Tat, Transactivating regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the lentiviruses Tat family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Secreted. Note=Probably localizes to both nuclear and nucleolar compartments. Nuclear localization is mediated through the interaction of the nuclear localization signal with importin KPNB1. Secretion occurs through a Golgi-independent pathway. Tat is released from infected cells to the extracellular space where it remains associated to the cell membrane, or is secreted into the cerebrospinal fluid and sera. Extracellular Tat can be endocytosed by surrounding uninfected cells via binding to several receptors depending on the cell type.
Protein: RL33_SHEB9
Sequence: MAKAKGNREKIKLVSTAKTGHFYTTEKNKRNMPEKMEIKKFDPVIRQHVIYKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: APAG_BRUSI
Sequence: MYSAVTRGIEVTVEPFYLEVQSEPEENRYVWGYRVTIVNNSSETVQLCSRYWQITDANGHVQEVRGSGVVGEQPVLDPGDSYQYSSGCPLTTSSGVMVGRYQMKGEDGAQFEIEIPAFSLDVPEQRRTLN
What are the official names of this protein?
Protein ApaG.
Protein: LANC3_MOUSE
Sequence: MDTKRCFANRFDDYQGSLLAGQCEEAVAPLVTSTIERILQELPPLGGGAEARGATGAGSSCQGGLYSGVAGVAYMLYHVSQSPLFAAARERYLRFAKRLIDACLRAEEWGETDADTRAAFLLGGAGVYAVATLVYHALGRPDYVQPLGKFRALCAVCAPVSFLDCGSDELFVGRAGYLCAALVLKQKLAQEVLTPTQIKAICQAILDSGKQYALKKRKPFPLMYSYYGTEYLGAAHGLSSILQMLLSYQEHLKPSDRELVWQSVDFLMEQEQNCNWPPELGETIERENELVHWCHGAPGIAYLFAKAYLISKKPQYLDTCIRCGELTWQKGLLKKGPGICHGVAGSAYVFLLLYRLTGNSKYIYRAQRFAQFLFTEEFKSGSRVLESIYSLYEGFSGTVCFLIDLLQPNQAEFPLFSVFV
What are the official names of this protein?
LanC-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the LanC-like protein family.
Protein: FDHE_SHESM
Sequence: MSHTAEIPMVPGSESPLELKPLKAVDPKTVYHRRAQRLLSLAKDSPLADYFELCRRVVAIQARLAAEADFGQLLAWGKDEAIPLSHLGSEADSYWQGLLQQLLSDLLPQVDEDMARVLRLLMQQSPEQLTSWGSALRQGHMSEVPARFSLFIWAAMGVYWSHWAPMVIKRIDQRKVVQQNLCPICGCHPVASVIVDQPRAGLRYLHCSLCESEWHYIRAHCTSCGQDKGTTLWSFDDAKAQVRIESCDECHGYTKMLFVEKSPLMDVAADDLATLMLDSELNAKGFGATTVNPLLLAHETEQ
What is the function of this protein?
Necessary for formate dehydrogenase activity.
What are the official names of this protein?
Protein FdhE homolog.
What is the protein family that this protein belongs to?
Belongs to the FdhE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI_CLOBB
Sequence: MKKGLTLDLSKTQAFVKDYELDYMEGMVKDSHDRLHSKTGQGNDFLGWIDLPVDYDKEEFARIKKAAEKIQSDSDVLIVIGIGGSYLGARAAIEMLTSNFHNVLDDNKRKVPKIFYAGNNISSTYMAELLEAIDGKDVSVNVISKSGTTTEPAIAFRIFKSYLEKKYGVEEARKRIYATTDKAKGALKGLADVEGYETFVIPDDVGGRFTVLTPVGLLPIAVAGINIDEMMQGAADAREAYSNPSLKENDCYKYAVTRNALYNKGKEIEVLVNYEPCIHYFNEWWKQLYGESEGKDKKGLFPAAVDFSTDLHSMGQYIQDGRRNLFETVINVEKARKEITIEFSEGDLDGLNFLTGKTMDFVNNKAFQGTLLAHNDGEVPNMVLNVPELSPYYFGHMVYFFEKACGISGYLLGINPFDQPGVEAYKKNMFALLGKPGYEDMKDELEKRL
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31_CAMC1
Sequence: MKKDIHPEYVDCTVTCACGNTFKTKSNKSEIRIDICDKCHPFFTGSEKIVDSAGRVEKFKKKYAQK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: TAA7C_RAT
Sequence: MATDDDSFPWDQDSILSRDLLSASSLQLCYENLNRSCVRSPYSPGSRLILYAVFGFGAVLAVCGNLLVMTSILHFRQLHSPANFLVASLACADLLVGLTVMPFSMVRSVEGCWYFGNTYCKFHSCFEGSFCYSSLFHLCFISLDRYIAVSDPLIYPTRFTASISGKCITFSWLLSIIYSFSLLYTGANEAGLEDLVSALTCVGGCQVAVNQSWVFINFLLFLVPALVMMTVYSKIFLIAKQQAQNIEKMSKQTARASESYKDRVAKRERKAAKTLGIAVAAFLLSWLPYFIDSIIDAFLGFITPTYMYEILVWIVYYNSAMNPLIYAFFYPWFRKAIKLIVTGKILRENSSTINLFPE
What is the function of this protein?
Orphan receptor.  Could be a receptor for trace amines.  Trace amines are biogenic amines present in very low levels in mammalian tissues.  Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative.  Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood (By similarity).
What are the official names of this protein?
Trace amine-associated receptor 7c, TaR-7c, Trace amine receptor 7c.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GLYA_MESH7
Sequence: MYKKIKLRDQQISELINLESKRQNSQIELIASENYASEDVILANGTSLSNKYGEGYPGKRYYGGCTFIDQIEKIAIERVKKLFKIEYANVQPYSGSSANAAVFAALLKPGDKILGLDLNAGGHLSHGYKINFSGMFYSGISYFLDENELLDYEAIEKIALKTKPNLIICGYSAYSRKIDFARFRQIADKVNAFLLADIAHIAGLIAAGQHPSPVGYAHIITSTTQKTLRGPRGGLILTSSKEIAAKIDKVVFPGIQGGPFFHTIAAKAVAFKEALEPWFKEYCAQIVKNAAHFASEFIKKGIRIVSQGTENHLFTIDVLSSYNLNGKQAQILLESVNIITNKNTIPNDTLSPFVTSGLRLGTPAMTSRGFKEQEFSQMAEIIDFVLRKKELNALEIKEIKKKVKILTKNFPIKKSYWP
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.
What are the official names of this protein?
Probable serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBPB1_BOVIN
Sequence: MLAFLILVTVTLASAHHSGEHFEGDKVFRVHVEDENHISLLHELASTRQMDFWKPDSVTQVKPHSTVDFRVKAEDTVAVEDFLGQNGLRYEVLISNLRSMLEAQFDSRVRTTGHSYEKYNNWETIEAWTEQVASENPDLISRSAIGTTFLGNTIYLLKVGKPGSNKPAVFMDCGFHAREWISPAFCQWFVREAVRTYGREIHMTEFLDKLDFYVLPVVNIDGYIYTWTTNRMWRKTRSTRAGSSCTGTDLNRNFDAGWCSIGASNNPCSETYCGSAAESEKESKAVADFIRNHLSSIKAYLTIHSYSQMMLYPYSYDYKLPKNNVELNTLAKGAVKKLASLHGTTYTYGPGASTIYPASGGSDDWAYDQGIKYSFTFELRDKGRYGFVLPESQIQPTCEETMLAIKYVTSYVLEHLY
What are the official names of this protein?
Carboxypeptidase B.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
Protein: KTHY_PSEA8
Sequence: MTGLFVTLEGPEGAGKSTNRDYLAERLRERGIEVQLTREPGGTPLAERIRELLLAPSDEPMAADTELLLMFAARAQHLAGVIRPALARGAVVLCDRFTDATYAYQGGGRGLPEARIAALESFVQGDLRPDLTLVFDLPVEIGLARAAARGRLDRFEQEDRRFFEAVRQTYLQRAAQAPERYQVLDAGLPLAEVQAGLDRLLPNLLERLNG
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: RSMI_MYCPN
Sequence: MPALKVIATPIGNIEEVSPRVKAALTKCEVLFCEDTRVTKKLLGLLGIDFSNKQFIINNEFKEKQNLSKVANLIHQYHCGLVSDAGYPSVSDPGHILVEYVRTQLPQIAIEVINGPSALVCGLVTSGFPESPLLFLGFLDHKPTQVTQTLKHYQNFQGTIVLFEAVHRLQQTLEVIQTVFSNTEVFVGRELTKLHESHYWFNTSAPLPDITLKGEFVIVINNHHTQPVGQYSDQLLKQEITQLVQMGVKVKDACHYLAKRLQLKSNKLYTLFHESD
What is the function of this protein?
Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase I, 16S rRNA 2'-O-ribose C1402 methyltransferase, rRNA (cytidine-2'-O-)-methyltransferase RsmI.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAZ_THET8
Sequence: MPFGEYQYSLDDKGRVVIPAPFRDFVEDGLVLTRGMEGCLYVFPLDRWKKIEEQLVNLPLTDAEARAFVRFFYSGAHKTRMDSASRVLIPPPLRLFAGLKEGGEVVIAGAPGRLEIWSQERWWKAIEEVLAKPPAPEALKGLVG
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RUVA_LEPBL
Sequence: MISGLKGTLKKLEVGYAHIETGGITYEVTISFKTYLELKSLPSHNEVQFQIFHAMNERGQKLFGFLTEQDKEFFKVIKGLQGIGELTALKILSFFSAEELYRIAQSGEAKELEKIPKVKGKTSEKIFFEVKQNLKKLELFLSGTSKEPSISLSSFSETPEEAALSRKREIAILGLVQLGFEEKTASKEVDKILKSSSPTDPGEIIREILKSL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: SODC_PEA
Sequence: MVKAVAVLSNSNEVSGTINFSQEGNGPTTVTGTLAGLKPGLHGFHIHALGDTTNGCISTGPHFNPNGKEHGAPEDETRHAGDLGNINVGDDGTVSFTITDNHIPLTGTNSIIGRAVVVHADPDDLGKGGHELSKTTGNAGGRVACGIIGLQG
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn].
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF1_STAEQ
Sequence: MAKQDVIELEGTVLDTLPNAMFKVELENGHEILAHVSGKIRMNYIRILPGDKVTVEMSPYDLSRGRITYRYK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y037_THEVO
Sequence: MIPAIIGTRPNNSIALHKSGIRLLGVDDSPFRRGQQKSFIVGVIMRLDGYIEKVMKAQITIDGNDVTERISNMALKFKDIVRVIVLSGISFGGFNICDIELLFKLTGIPVISLFEKGGSASEMINAINKHLGDQEKIGILKRLKPIALNNNGYTIMANLAGIESESASRIIRMNTVRGKMPEAVRVPDLIAKIL
What are the official names of this protein?
UPF0215 protein TV0037.
What is the protein family that this protein belongs to?
Belongs to the UPF0215 family.
Protein: IXTPA_TREPA
Sequence: MRAVDFLRRATVCWYMRIYLASNNAHKHAEFSSLFPMHTILLPKDEGIDFFSPEDGSTFFANARQKADALYDVVHAPVLADDSGLCVDALDGDPGVHSARFGAQHGVHTDTARMQLLLERMHGRQDRACSFVCVAVLKLGSVPLCVGRGVCRGVLTTEMSGVEGFGYDPIFLLPHLGRTFAQLSIEEKNRVSHRALAALRLAQVLAMMQLPRALRYELKLLRGARRMTRGGVLRPGAPCAQRKGQTAQTARRHKFYARARRCARRIHRA
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: PYRE_ENTFO
Sequence: MTKVAKKIAKDLLDIEAVFLNPNEPFTWASGIKSPIYCDNRITMSYPAVRKEIAEGLAAKIKETFPEVEVIAGTATAGIPHAAWVADILGLPMVYIRSKAKDHGKGNQIEGRISEGQKMVVIEDLISTGGSVLEAAEAAEREGATVLGVAAIFTYELPKGTANFADKQMTLLTLTNYSTLIDAALEANYIEEKDVTLLQEWKKDPENWGK
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: MDH_YERPE
Sequence: MKVAVLGAAGGIGQALALLLKTQLPSGSDLSLYDIAPVTPGVAVDLSHIPTAVNIKGFSGEDATPALQGADIVLISAGVARKPGMDRSDLFNVNAGIVRNLVEQIARTCPNALIGIITNPVNTTVAIAAEVLKKAGVYDKNKLFGITTLDTIRSNTFVAELKGKQPQDIEVPVIGGHSGVTILPLLSQIPGVSFTEQEVADLTKRIQNAGTEVVEAKAGGGSATLSMGQAAARFGLSLVRALQGESNVVECSYVEGDGKYARFFAQPILLGKNGVAERKDIGKLSAFEQQALENMLDVLHKDIELGEKFVNQ
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: HPCR_SHIFL
Sequence: MHDSLTIALLQAREAAMSYFRPIVKRHNLTEQQWRIVRILAESPSMDFHDLAYRACILRPSLTGILTRMERDGLVLRLKPINDQRKLYISLTKEGQALYNRAQTQIEEAYRQIEAQFTAEKMQQLTHLLEEFIALGNSRQEDIPGDNE
What is the function of this protein?
Repressor for the homoprotocatechuate catabolic pathway hpc operon.
What are the official names of this protein?
Homoprotocatechuate degradative operon repressor.