PharMolix/UniProtQA huggingface dataset:
Protein: COPG1_MOUSE
Sequence: MLKKFDKKDEESGGGSNPLQHLEKSAVLQEARVFNETPINPRKCAHILTKILYLINQGEHLGTTEATEAFFAMTKLFQSNDPTLRRMCYLTIKEMSCIAEDVIIVTSSLTKDMTGKEDNYRGPAVRALCQITDSTMLQAVERYMKQAIVDKVPSVSSSALVSSLHLLKCSFDVVKRWVNEAQEAASSDNIMVQYHALGLLYHVRKNDRLAVSKMISKFTRHGLKSPFAYCMMIRVASKQLEEEDGSRDSPLFDFIESCLRNKHEMVVYEAASAIVNLPGCSAKELAPAVSVLQLFCSSPKAALRYAAVRTLNKVAMKHPSAVTACNLDLENLVTDSNRSIATLAITTLLKTGSESSIDRLMKQISSFMSEISDEFKVVVVQAISALCQKYPRKHAVLMNFLFTMLREEGGFEYKRAIVDCIISIIEENSESKETGLSHLCEFIEDCEFTVLATRILHLLGQEGPKTNNPSKYIRFIYNRVVLEHEEVRAGAVSALAKFGAQNEEMLPSILVLLKRCVMDDDNEVRDRATFYLNVLEQKQKALNAGYILNGLTVSIPGLEKALQQYTLEPSEKPFDLKSVPLATTPMAEQRPESTATAAVKQPEKVAATRQEIFQEQLAAVPEFQGLGPLFKSSPEPVALTESETEYVIRCTKHTFSDHLVFQFDCTNTLNDQTLENVTVQMEPTEAYEVLSYVPARSLPYNQPGTCYTLVALPTEDPTAVACTFSCVMKFTVKDCDPNTGEIDEEGYEDEYVLEDLEVTVADHIQKVMKVNFEAAWDEVGDEFEKEETFTLSTIKTLEEAVGNIVKFLGMHPCERSDKVPENKNTHTLLLAGVFRGGHDILVRSRLLLLDTVTMQVTARSSEELPVDIILASVG
What is the function of this protein?
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.  Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.  In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity).  Required for limiting lipid storage in lipid droplets.  Involved in lipid homeostasis by regulating the presence of perilipin family members PLIN2 and PLIN3 at the lipid droplet surface and promoting the association of adipocyte triglyceride lipase (PNPLA2) with the lipid droplet surface to mediate lipolysis.
What are the official names of this protein?
Coatomer subunit gamma-1, Gamma-1-coat protein, Gamma-1-COP.
What is the protein family that this protein belongs to?
Belongs to the COPG family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it. Predominantly located in the cis- Golgi apparatus.
Protein: CMOB_SHEB2
Sequence: MISFSSFYQQIADSNLQHWLETLPSILGKWQRDHKHGNLPKWEKVLNKLHYPAPDQVDFVDSVTVGSGEQLSPGEKEKLENLLRLFMPWRKGPFHIHGIHIDTEWRSDWKWDRVKQHISPLKNRTVLDVGCGSGYHMWRMLGSGAKRVVGIDPSPLFLCQFEAVKRLAGTHHPVHLLPLGIEELPPLDAFDTVFSMGVLYHRRSPIDHLLQLRDQLRTGGELVLETLVIDGDENAVLVPQDRYGKMNNVWFIPSVAALMLWLKKCDFTDIRCVDTDVTALAEQRRTDWMPNESLVEYLDPNDITKTVEGYPAPKRATIIAVKNQPNQDLIS
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: LPXC_PECAS
Sequence: MIKQRTLKRIVQATGVGLHTGKKVTLTMRPAPANTGVIYRRTDLNPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIDVDAPEIPIMDGSASPFVYLLLDAGIEELNCAKKFVRIKQSVRVEDGDKWAEMKPFNGFSLDFTIDFNHPAIDAGNQRYRLDFSADAFVRQISRARTFGFMRDIEYLQSRGLCLGGSMDCAIVVDDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFSAFKSGHALNNKLLQAVLANQEAWEYVTFEDEAEMPLAFKAPSIVLA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: YDGA_ECOLI
Sequence: MNKSLVAVGVIVALGVVWTGGAWYTGKKIETHLEDMVAQANAQLKLTAPESNLEVSYQNYHRGVFSSQLQLLVKPIAGKENPWIKSGQSVIFNESVDHGPFPLAQLKKLNLIPSMASIQTTLVNNEVSKPLFDMAKGETPFEINSRIGYSGDSSSDISLKPLNYEQKDEKVAFSGGEFQLNADRDGKAISLSGEAQSGRIDAVNEYNQKVQLTFNNLKTDGSSTLASFGERVGNQKLSLEKMTISVEGKELALLEGMEISGKSDLVNDGKTINSQLDYSLNSLKVQNQDLGSGKLTLKVGQIDGEAWHQFSQQYNAQTQALLAQPEIANNPELYQEKVTEAFFSALPLMLKGDPVITIAPLSWKNSQGESALNLSLFLKDPATTKEAPQTLAQEVDRSVKSLDAKLTIPVDMATEFMTQVAKLEGYQEDQAKKLAKQQVEGASAMGQMFRLTTLQDNTITTSLQYANGQITLNGQKMSLEDFVGMFAMPALNVPAVPAIPQQ
What are the official names of this protein?
Protein YdgA.
What is the protein family that this protein belongs to?
To E.coli YihF and H.influenzae HI_1236.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Periplasmic side. Note=Has been isolated in association with the inner membrane, suggesting it may be tethered to the membrane.
Protein: CASA2_RABIT
Sequence: MKFFIFTCLLAVALAKPKIEQSSSEETIAVSQEVSPNLENICSTACEEPIKNINEVEYVEVPTEIKDQEFYQKVNLLQYLQALYQYPTVMDPWTRAETKAIPFIRTMQYKQEKDATKHTSQKTELTEEEKAFLKYLDEMKQYYQKFVFPQYLKNAHHFQKTMNPWNHVKTIIYQSVPTLRYL
What is the function of this protein?
Important role in the capacity of milk to transport calcium phosphate.
What are the official names of this protein?
Alpha-S2-casein, Alpha-S2B-casein.
What is the protein family that this protein belongs to?
Belongs to the alpha-casein family.
What are the subcellular locations of this protein?
Secreted.
Protein: LPTD_ECOUT
Sequence: MKKRIPTLLATMIATALYSQQGLAADLASQCMLGVPSYDRPLVQGDTNDLPVTINADHAKGDYPDDAVFTGSVDIMQGNSRLQADEVQLHQKEAPGQPEPVRTVDALGNVHYDDNQVILKGPKGWANLNTKDTNVWEGDYQMVGRQGRGKADLMKQRGENRYTILDNGSFTSCLPGSDTWSVVGSEIIHDREEQVAEIWNARFKVGPVPIFYSPYLQLPVGDKRRSGFLIPNAKYTTTNYFEFYLPYYWNIAPNMDATITPHYMHRRGNIMWENEFRYLSQAGAGLMELDYLPSDKVYKDEHPNDDSSRRWLFYWNHSGVMDQVWRFNVDYTKVSDPSYFNDFDNKYGSSTDGYATQKFSVGYAVQNFNATVSTKQFQVFSEQNTSSYSAEPQLDVNYYQNDVGPFDTRIYGQAVHFVNTRDDMPEATRVHLEPTINLPLSNNWGSINTEAKLLATHYQQTNLDWYNSRNTTKLAESANRVMPQFKVDGRMVFERDMEMLAPGYTQTLEPRAQYLYVPYRDQSKIYNYDSSLLQSDYSGLFRDRTYGGLDRIASANQVTTGVTSRIYDDAAVERFNISVGQIYYFTESRTGDDNITWENDDKTGSLVWAGDTYWRISDRWGLRGGIQYDTRLDNVATSNSSIEYRRDEDRLVQLNYRYASPEYIQATLPKYYSTAEQYKNGISQVGAVASWPIADRWSIVGAYYYDTNANKQADSMLGVQYSSCCYAIRVGYERKLNGWDNDKQHAVYDNAIGFNIELRGLSSNYGLGTQEMLRSNILPYQNTL
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: ATPF_PARDP
Sequence: MKRLSVLFALVASPALAASGPFFSLRNTDFIVTLAFLLFVGILVYFRVPQIVGGLLDKRAEGIRNDLAEARRLREEAQEIYASYERRQREVKSQADDIVANAKREAVAEAEKAKKALQLSIERRLKAAEEQIAGAEAEAVRAVRDRAIQTAIAAATEILGKQASPAERSAGIDKAIDEVAQRLN
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: GLYA2_AGRFC
Sequence: MLNRLSHNTVSDTVIADAIAEELDRQKTQIELIASENIVSADVLAAQGSVLTNKYAEGYPGKRYYGGCEFVDKVEQVAIDRLKQLFGAEFANVQPHSGAQANQAVFLALLQPGDRIMGLSLAHGGHLTHGSPVTMSGKWFDVVSYEVDPETHLIDMEKVREKALETKPKLIVAGASAYPRQIDFAGFREIADEVGAYLMVDMAHYAGLIAGGHYPNAVPHAHVTTSTTHKTLRGPRGGVILTNDADLAKKLNSAVFPGNQGGPLMHVIAAKAVAFGEALRPEFSDYAGQVIANAQALAKVLIQGGLGIVSGGTDSHMVLVDLRPKGVTGKIAEIALERAGLTCNKNSIPNDPEKPFVTSGIRLGSSAGTTRGFGVLEFEKIGALILRVIDALATNAEGDSAVEAEVREEVAALCEAFPIYVS
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase 2, SHMT 2, Serine methylase 2.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 5S_PROFR
Sequence: MSPREIEVSEPREVGITELVLRDAHQSLMATRMAMEDMVGACADIDAAGYWSVECWGGATYDSCIRFLNEDPWERLRTFRKLMPNSRLQMLLRGQNLLGYRHYNDEVVDRFVDKSAENGMDVFRVFDAMNDPRNMAHAMAAVKKAGKHAQGTICYTISPVHTVEGYVKLAGQLLDMGADSIALKDMAALLKPQPAYDIIKAIKDTYGQKTQINLHCHSTTGVTEVSLMKAIEAGVDVVDTAISSMSLGPGHNPTESVAEMLEGTGYTTNLDYDRLHKIRDHFKAIRPKYKKFESKTLVDTSIFKSQIPGGMLSNMESQLRAQGAEDKMDEVMAEVPRVRKAAGFPPLVTPSSQIVGTQAVFNVMMGEYKRMTGEFADIMLGYYGASPADRDPKVVKLAEEQSGKKPITQRPADLLPPEWEKQSKEAATLKGFNGTDEDVLTYALFPQVAPVFFEHRAEGPHSVALTDAQLKAEAEGDEKSLAVAGPVTYNVNVGGTVREVTVQQA
What is the function of this protein?
The 5S subunit specifically catalyzes the transfer of the carboxyl group from biotin of the 1. 3S subunit to pyruvate to form oxaloacetate and 1. 3S biotin.
What are the official names of this protein?
Methylmalonyl-CoA carboxyltransferase 5S subunit, Transcarboxylase 5S subunit.
Protein: DNAJ_LIMF3
Sequence: MAEEDLYDVLGVKKDASEAEIKRAYRKLAAKYHPDVNHEPGAEKKFKKINEAYETLSDDQKRAQYDQFGTTGSQAGGFGGQGGFGGFGQGGFSQGGFGDFSDIFGDIFGGGRARRDPSAPQQGRDLQYTMTLDFMDAVFGKETSIKYNRSAECHTCHGSGAKPGKSAHTCSTCHGQGYVLRQRQTMMGMMQSQEVCPTCGGKGQVIDPADQCDTCHGAGVTEERHELKVKVPQGIDDGQQMRLQGQGEAGKNGGPYGDLYIVFRVTPSRDFKRDGNTIYVDQDISISQATLGDHVQAKTVHGDVDLKIPAGTQSETKFRLRGKGVPRVNGNGNGDEYVTVHVKTPKTLNKRQREAMLAFAAASGEDVKGVKAGFFDKLKDAFEDNK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EF1A_BLAAD
Sequence: MGKEKTHVNVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERERVITIDIALWKFETPKYYVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGTGEFEAGISKDGQTREHALLAFTLGVRQLIVAINKMDSVNWSEDRYNEIVKETSNFIKKVGFNPKAVPFVPISGWNGDNMIEATTNASWYKGWHKETKEGKATGKTLLEAIDAVDPPTRPSDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLPEGLPGDNVGFNVKNVSVKEIRRGNVAGDSKNDPPKGCDSFTAQVIIFNHPGQISAGYSPVLDCHTAHIACRFDELIEKIDRRSGKKVEDSPKFVKAGDAAIVRMIPSKPMCVETFTEYPPLGRFAVRDMRQTVAVGVIKSVEKSDKGAGKVTKAAQKAAKK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha, EF-1-alpha.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPH_BURVG
Sequence: MTSSLSRPSGRRADELRKVALTRHYTKHAEGSVLVEFGDTKVICTASVVERVPEFLRERGQGWLTAEYGMLPRATHTRSDREAARGKQTGRTQEIQRLIGRALRAVFDLEALGPRTINIDCDVIQADGGTRTASITGAFVAAHDAVSKLIAAGKLARSPITDHVAAISVGVYEGAPVLDLDYAEDSRCDTDMNVVMTGAGGFVEVQGTAEGVPFSRAEMNALLDLAQAGIGRLVQLQKDVLGADHV
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: RISB_HELPY
Sequence: MQIIEGKLQLQGNERVAILTSRFNHIITDRLQEGAMDCFKRHGGDEDLLDIVLVPGAYELPFILDKLLESEKYDGVCVLGAIIRGGTPHFDYVSAEATKGIAHAMLKYSMPVSFGVLTTDNIEQAIERAGSKAGNKGFEAMSTLIELLSLCQTLKG
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: RF1_STAA1
Sequence: MFDQLDIVEERYEQLNELLSDPDVVNDSDKLRKYSKEQADLQKTVDVYRNYKAKKEELADIEEMLSETDDKEEVEMLKEESNGIKAELPNLEEELKILLIPKDPNDDKDVIVEIRAAAGGDEAAIFAGDLMRMYSKYAESQGFKTEIVEASESDHGGYKEISFSVSGNGAYSKLKFENGAHRVQRVPETESGGRIHTSTATVAVLPEVEDVEIEIRNEDLKIDTYRSSGAGGQHVNTTDSAVRITHLPTGVIATSSEKSQIQNREKAMKVLKARLYDMKVQEEQQKYASQRKSAVGTGDRSERIRTYNYPQSRVTDHRIGLTLQKLGQIMEGHLEEIIDALTLSEQTDKLKELNNGEL
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P32K_ADEO7
Sequence: MYVTNNTALAGGAYRKRKKKFQRPKPRKRARKSKKPPKSENTYVQRFWKNPPRNYILKEPTKPISSYARWIPPEIVDVNNITVNIPNTITASRLPKTEFQETEVFKDARDQWYFPIRPSDGEHDTDVKVKKKWSLDTVLQFLQSSPKHIRQLLLTSLFGSLLGLILDTLFGGPWNLTSRLLRLIISVVPGGRILLTALDGLGYFLGNSANPIHLIENPMMQAFGNSIQKQISPRLAEDIIKAADEQIGGGFMRTIASILSAAASAGTHFTMALPAIPIAAVRPFMR
What are the official names of this protein?
Structural protein p32K.
What is the protein family that this protein belongs to?
Belongs to the atadenoviridae p32K protein family.
What are the subcellular locations of this protein?
Virion.
Protein: ICP22_VZVO
Sequence: MFCTSPATRGDSSESKPGASVDVNGKMEYGSAPGPLNGRDTSRGPGAFCTPGWEIHPARLVEDINRVFLCIAQSSGRVTRDSRRLRRICLDFYLMGRTRQRPTLACWEELLQLQPTQTQCLRATLMEVSHRPPRGEDGFIEAPNVPLHRSALECDVSDDGGEDDSDDDGSTPSDVIEFRDSDAESSDGEDFIVEEESEESTDSCEPDGVPGDCYRDGDGCNTPSPKRPQRAIERYAGAETAEYTAAKALTALGEGGVDWKRRRHEAPRRHDIPPPHGV
What is the function of this protein?
Immediate early (EI) protein that functions as a transcriptional regulator of cellular and viral mRNAs mainly by interacting with several general transcription factors thereby disorganizing the preinitiation complex at certain promoters.  May additionally help to regulate levels of histones in virus-infected cells by interacting with host ASF1.  By inhibiting host transcriptional program, IE63 plays a major role in the ability of VZV to overcome the innate immune response to the virus (By similarity).
What are the official names of this protein?
Transcriptional regulator ICP22 homolog, Immediate-early protein 63, IE63, Transcriptional transactivator IE63.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae ICP22 family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Virion tegument. Note=During the first stage of infection, IE63 is mostly expressed in the nucleus and also slightly in the cytoplasm, and during latency, IE63 localizes in the cytoplasm quite exclusively.
Protein: IF1_GLUOX
Sequence: MSKEDLIEFTGTVMELLPNAMFRVTLDNEHTILAHTSGKMRKNRIRVLAGDRVNVEMTPYDLSKGRITFRFK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POL_FMVD
Sequence: MTSSSLFREGELGHFCLNKQEMLHLNVTNPNSIYIEGKLSFEGYKSFNIHCYVDTGASLCIASRYIIPEELWENSPKDIQVKIANQELIKITKVCKNLKVKFAGKSFEIPTVYQQETGIDFLIGNNFCRLYNPFIQWEDRIAFHLKNEMVLIKKVTKAFSVSNPSFLENMKKDSKTEQIPGTNISKNIINPEERYFLITEKYQKIEQLLDKVCSENPIDPIKSKQWMKASIKLIDPLKVIRVKPMSYSPQDREGFAKQIKELLDLGLIIPSKSQHMSPAFLVENEAERRRGKKRMVVNYKAINQATIGDSHNLPNMQELLTLLRGKSIFSSFDCKSGFWQVVLDEESQKLTAFTCPQGHFQWKVVPFGLKQAPSIFQRHMQTALNGADKFCMVYVDDIIVFSNSELDHYNHVYAVLKIVEKYGIILSKKKANLFKEKINFLGLEIDKGTHCPQNHILENIHKFPDRLEDKKHLQRFLGVLTYAETYIPKLAEIRKPLQVKLKKDVTWNWTQSDSDYVKKIKKNLGSFPKLYLPKPEDHLIIETDASDSFWGGVLKARALDGVELICRYSSGSFKQAEKNYHSNDKELLAVKQVITKFSAYLTPVRFTVRTDNKNFTYFLRINLKGDSKQGRLVRWQNWFSKYQFDVEHLEGVKNVLADCLTRDFNA
What is the function of this protein?
Encodes for at least two polypeptides: protease (PR) and reverse transcriptase (RT).  The protease processes the polyprotein in cis.  Reverse transcriptase is multifunctional enzyme that converts the viral RNA genome into dsDNA in viral cytoplasmic capsids.  This enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes in a partially processive 3'- to 5'-endonucleasic mode.  Neo-synthesized pregenomic RNA (pgRNA) are encapsidated, and reverse-transcribed inside the nucleocapsid.  Partial (+)DNA is synthesized from the (-)DNA template and generates the relaxed circular DNA (RC-DNA) genome.  After budding and infection, the RC-DNA migrates in the nucleus, and is converted into a plasmid-like covalently closed circular DNA (cccDNA) (By similarity).
What are the official names of this protein?
Enzymatic polyprotein.
What is the protein family that this protein belongs to?
Belongs to the caulimoviridae enzymatic polyprotein family.
Protein: RHG36_BOVIN
Sequence: MPPLLLLSALIFLVNVLGGAPGHNPNRRAKMISIHSLSELERLKLQEAAYHELVARQFLSEFKPERALPTDRSNTFEKWFLILRGQERAVSLKTFGIRLEEVLVNELTRRKQVELRATMQMQEAAGPATSGRRRGNAVQRMFGRIRRIFSGRRDEPFLPREFTRRGRRGAVSADSLAELEGGALLLQTLQLSRISFPIGQRLLGSKRKMSLNPIAKQIPHVVEACCSFIEKHGLSTVGIFTLEYSEKRVRKLREEFDQGLDVVLDDSQNVHDVAALLKEFFRDMKDSLLPDDLYMSFLQTATLKPQDQLSALQLLVYLMPPCHSDTLERLLKVLHKVAENCEDSIGIDGQLVSGNRMTSTNLALVFGSALLKKGASAKRESRKTRLGIDHYVASVSVVRAMIDNWDVLFQVPPHIQKQVAKRVWKSSPEALDFIRRRNLRKIQSERIKMEEDALLSDPVETSAEARAAILGQSKPFDEGSSEEPAVPPGTARSHDDEEGAGNPLILEQDRPLLRVPREKEAKTGIGYFFP
What is the function of this protein?
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
What are the official names of this protein?
Rho GTPase-activating protein 36.
Protein: BIOF_PHOLL
Sequence: MDWSSYLSRQLSERRSTSLWRQRQVNQKSDGRFLYAADGKYLNFSSNDYLGLSANPAIISAWQRGAEQYGVGSGGSGHITGYTKAHQLLEQQLADWLGYPKALLFISGYSANQGVIAALMTEQDRIIADRLSHASLMEAAMHSPAQLRRFLHNQPESLANLLATPCVGKTLVVTEGVFSMDGDCAPLADIHQQTRISGNWLMVDDAHGIGVCGEQGRGSCWQQKVKPEILIVTFGKAFGLSGAAVLCDEQTAEYLIQYARHLIYSTSMPPAQAQALSEAVRQIQSGDELRQRLQQNINYFRRQAQKLPFNLTDSTTAIQPLIVSDNELSVSLSQSLQQKGIWVKAIRPPTVPPGSARLRITLTASHMPQDIDMLMEALHGFRS
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: EXE4_HELSC
Sequence: MKIILWLCVFGLFLATLFPISWQMPVESGLSSEDSASSESFASKIKRHGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPSG
What is the function of this protein?
Venom protein that mimics the incretin hormone glucagon-like peptide 1 (GLP-1).  It stimulates insulin synthesis and secretion, protects against beta-cell apoptosis in response to different insults, and promotes beta-cell proliferation It also promotes satiety, reduces food intake, reduces fat deposition, reduces body weight and inhibits gastric emptying.  Interacts with GLP-1 receptor (GLP1R).  Induces hypotension that is mediated by relaxation of cardiac smooth muscle.
What are the official names of this protein?
Exendin-4.
What is the protein family that this protein belongs to?
Belongs to the glucagon family.
What are the subcellular locations of this protein?
Secreted.
Protein: MLIC_CUPNH
Sequence: MTTRPILSCARAVALLATLGACAAAHAARAPGIDGVRFPDVRAVRYQCDGGKTLSVRYFNSPDNQAAVFRIDGKPVLAVSTVSASGARYAGGRYEWWTKGEEGTLRDLMQAENAAPALANCQAKP
What is the function of this protein?
Specifically inhibits C-type lysozymes.
What are the official names of this protein?
Membrane-bound lysozyme inhibitor of C-type lysozyme.
What is the protein family that this protein belongs to?
Belongs to the MliC family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Note=Anchored to the periplasmic side.
Protein: RISB_PECAS
Sequence: MNVIEGVVATPDARVAIAIARFNHFINDSLLQGAIDALKRIGQVKDENITVVWVPGAYELPLAVRALTKSAKNGGYDAVIALGTVIRGGTAHFEFVAGECSSGLSSVAMDSEIPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVLKAIK
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: MURQ_FRATT
Sequence: MNILENINTEKRNPRSLNLDSMSIAEAVSLMIDEEYGVIEALKEQHRNITEVILATSYSLRNGGRIIYIGAGTSGRLGILDAVECPPTFSVDYNTIVGLIAGGEKAFIQAQEGAEDDANFGKEDLQSINLTAKDIVIGIAASGRTPYVIGALEYANSIGATTVAISCTKQAKISKYAKYSIEAVPGPEVLTGSTRLKAGTTQKLILNMISTLSMVSVGKVYQNLMVDVKPTNQKLIERSKNIVCEATGVDYTTAEKFYLKANKSVKVAIVMILNNCDYEKALAILKNNNNFIKS
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.  Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.