PharMolix/UniProtQA huggingface dataset:
Protein: ARGR_EXIS2
Sequence: MTKGQRLIKIREIITQSEIETQDELVEELRNAGYKVTQATVSRDIKELHLVKVPLNDGRYKYSLPADQRFNPLGKLRRLLGDSFISIDSAQNLIVMHVLPGNANALGVLLDHLNWPELLGTVCGDDTILMITRNEEAATEVTERILGML
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UT1_HUMAN
Sequence: MEDSPTMVRVDSPTMVRGENQVSPCQGRRCFPKALGYVTGDMKELANQLKDKPVVLQFIDWILRGISQVVFVNNPVSGILILVGLLVQNPWWALTGWLGTVVSTLMALLLSQDRSLIASGLYGYNATLVGVLMAVFSDKGDYFWWLLLPVCAMSMTCPIFSSALNSMLSKWDLPVFTLPFNMALSMYLSATGHYNPFFPAKLVIPITTAPNISWSDLSALELLKSIPVGVGQIYGCDNPWTGGIFLGAILLSSPLMCLHAAIGSLLGIAAGLSLSAPFEDIYFGLWGFNSSLACIAMGGMFMALTWQTHLLALGCALFTAYLGVGMANFMAEVGLPACTWPFCLATLLFLIMTTKNSNIYKMPLSKVTYPEENRIFYLQAKKRMVESPL
What is the function of this protein?
Mediates the transport of urea driven by a concentration gradient across the cell membrane of erythrocytes (PubMed:7989337, PubMed:10514515, PubMed:7797558, PubMed:8997401).  Also mediates the transport of urea across the cell membrane of the renal inner medullary collecting duct which is critical to the urinary concentrating mechanism (By similarity).  Facilitates water transport in erythrocytes (By similarity).
What are the official names of this protein?
Urea transporter 1, Solute carrier family 14 member 1, Urea transporter, erythrocyte.
What is the protein family that this protein belongs to?
Belongs to the urea transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Note=Restricted to the basolateral membrane in various portions of the urothelium.
Protein: Y012_SFAVA
Sequence: MMSSVTSEIIHTDVSGQRVRPPLTYCNGELGLKNSEDAAYFCLEKFKSFNEVPDFQYIYLTLSLHVPPPTRKYLLKFHKRLLNVCRLCGETGDLVGGRVLVSGVSQKTADIVVSAKSNGEVLYDWSNFFKSTVRVRCRYTIAKLYNNKAAMREIAKQKNWQTTYPNLEAYRKLNDAAKNSKHTPIVSIQTPPPPAPTPNRPDVPASKNVVITQRYQKPVEKIEDSRLETTRISVIPLLSVLLLVIIIILL
What are the official names of this protein?
Uncharacterized protein ORF12.
What is the protein family that this protein belongs to?
Belongs to the ascovirus HvAV ORF18 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: AGAL_BACTN
Sequence: MKKLTFLLLCVLCTLSLQAQKQFTLASPDGNLKTTITIGDRLTYDITCNGRQILTPSPISMTLDNGTVWGENAKLSGTSRKSVDEMIPSPFYRASELRNHYNGLTLRFKKDWNVEFRAYNDGIAYRFVNQGKKPFRVVTEVSDYCFPSDMTASVPYVKSGKDGDYNSQFFNSFENTYTTDKLSKLNKQRLMFLPLVVDAGDGVKVCITESDLENYPGLYLSASEGANRLSSMHAPYPKRTVQGGHNQLQMLVKEHEDYIAKVDKPRNFPWRIAVVTTTDKDLAATNLSYLLGAPSRMSDLSWIKPGKVAWDWWNDWNLDGVDFVTGVNNPTYKAYIDFASANGIEYVILDEGWAVNLQADLMQVVKEIDLKELVDYAASKNVGIILWAGYHAFERDMENVCRHYAEMGVKGFKVDFMDRDDQEMTAFNYRAAEMCAKYKLILDLHGTHKPAGLNRTYPNVLNFEGVNGLEQMKWSSPSVDQVKYDVMIPFIRQVSGPMDYTQGAMRNASKGNYYPCYSEPMSQGTRCRQLALYVVFESPFNMLCDTPSNYMREPESTAFIAEIPTVWDESIVLDGKMGEYIVTARRKGDVWYVGGITDWSARDIEVDCSFLGDKSYHATLFKDGVNAHRAGRDYKCESFPIKKDGKLKVHLAPGGGFALKIK
What is the function of this protein?
Galactosidase that is able to hydrolyze the alpha-1,6 disaccharide melibiose and the synthetic p-nitrophenyl alpha-galactoside substrate (pNP-Gal), with retention of the anomeric configuration.  Does not hydrolyze DNP-Glc or pNP-Glc.
What are the official names of this protein?
Retaining alpha-galactosidase, BtGH97b, Melibiase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 97 family.
Protein: ABCGN_DICDI
Sequence: MGDNIVINLNNVSRSYGNVKVIEKLNFTINKGTINSLIGSSGSGKTTILKTILGKLKQDDGIVQVFGKEPCGKGSEIPGSSVGYAPQDVCLYNEITIEETLSFFASIHRMPKDEYIKKRDSLVEILELPSLSKIISELSGGQQRRVSLATALIHSPKLLILDEPTVGVCPLVSSKIWEHLIFLTKNFGVTIIITTHYLQECRSCDNIFLLRNGRILESGPPNYLLSKYECSLLEDVYYKLCRGDEEISLQLIDSKNNEKINRDINTSIPLEFISNGANINNDDILISNTNKPIIKKDAKIYKERLSDFKNKLQIWFSHSITISIRKLTQMYRLKFPLVFEIISPSLLITLFFLAIGNVPHDLKFGIKNIDSGSLSGDFINALSDGNNIFNFIQINDTSNAIQMIESSDLWGLIDIPVNFTNGMINKLFNPLEKSFENSEMEIYMDLSNFQMNLMVDVQFQKAFNKIANDSGIKLLPTNFHAVYGDQNANFNWFLAPAMICIITYVHCMNFLSITFVREKNDGTRDRILLYGVSPVSNVLGHILAHIPILLVQFSIQLLIAVFAFGVPIKGNIVLIYLFFILINTVGMCQGILISLISKAEVDAVQLCLAIFICSLCMAGIIWPTEAIITFGWISNLVPTKWSGLALRGIMIKDLPFSHQHIWKSLIIIISYIIGTFSLIVISTPIGDRNFNFKKLFKRIKK
What are the official names of this protein?
ABC transporter G family member 23, ABC transporter ABCG.23.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CC169_MOUSE
Sequence: MGEGHGDTFEGVSTDRLKLELLEEIHMKDVVQLSTLEIRHKIAELEANLNGDLAGSEWKTRYETQLELNDQLEKQIVSLKEKMEKMRGNPSDRLSSIRVYEKMPVESLNVLLKQLEKEKRSLESQVKEYAFRLEQESKAYHRTNNERRSYIAEMTQVSGSNQVSKRQQMDPLPRMKESPVKTGRHNSMNQKTTNAKKGPVKKVPRSNHLPKLNP
What are the official names of this protein?
Coiled-coil domain-containing protein 169.
What is the protein family that this protein belongs to?
Belongs to the CCDC169 family.
Protein: RIMO_SULNB
Sequence: MPSRKKLHLISLGCTKNLVDSEVMLGRLKEYEITDDNTEADVIIVNTCGFIDAAKEESINTVLNLHDERKEDSILVMSGCLSERYKEELQQDMPEIDIFTGVGDYEKIDELIASKQSTFSPEVYLATETSGRVITGSNYHAYIKIAEGCNQACSFCAIPSFKGKLHSRSLSSIEKEVRMLAEQGYYDFSFISQDSSSYGRDMDLKDGLIDLIKVVEAIEGVRSARILYLYPSTTTFELIDTIADSKIFQTYYDMPIQHIDDAVLKTMKRGFGEQKTIELLEHMKSKPNAFLRTSVIAGHPGESQRSFEKLCSFMEEFGFDRFNTFHYSNEETTTAYQMEQIPQDIINERAEILGEIAERSTLRSLEKMVGKTVELVIDGESDEHEYLLSARPLQWAVDIDGEILINDTSDLPVKYGKVYEAKVTELVGMQLLATLIKEC
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPX_BURMA
Sequence: MFNWVKTAMLMAAITALFIVIGGMIGGSRGMTIALLIALGMNFFSYWFSDKMVLRMYNAQEVDEATAPQFYRMVRELATRANLPMPRVYLIDENQPNAFATGRNPEHAAVAATTGILRVLSEREMRGVMAHELAHVKHRDILISTISATMAGAISALANFAMFFGGRDENGRPANPIAGIAVALLAPIAGALIQMAISRAREFEADRGGAQISGDPQALASALDKIHRYASGIPFQTAEEHPATAQMMIMNPLSGGGLQNLFSTHPATEERIARLMDMARTGRFD
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CRVP_PSETE
Sequence: MIAFLVLLSLAAVLQQSSGTVDFASESSNKNDYQKEIVDKHNDLRRSVKPTARNMLQMKWNSRAAQNAKRWANRCTFAHSPPYTRTVGKLRCGENIFMSSQPFAWSGVVQAWYDEVKKFVYGIGAKPPSSVTGHYTQVVWYKSHLLGCASAKCSSTKYLYVCQYCPAGNIVGSIATPYKSGPPCGDCPSACDNGLCTNPCKHNDDLSNCKTLVKKHKCQTEWIKSKCPATCFCRTEII
What is the function of this protein?
Blocks olfactory (CNGA2) and retinal (CNGA1) CNG channel currents.  Does not affect neither depolarization- nor caffeine-induced contraction of smooth muscle (By similarity).
What are the official names of this protein?
Cysteine-rich venom protein pseudechetoxin-like, CRVP.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Secreted.
Protein: UBIE_PSYIN
Sequence: MSNQAENTTHFGFKTVQEDTKADLVAGVFHSVAAKYDIMNDVLSMGVHRIWKRFTVDCSGIRKGQKVLDLAGGTGDLTAKFSRIVGQTGQVTLADINDSMLKVGRSKLRDLGIVGNVSYVQANAEELPFPDNHFDLITIAFGLRNVTDKDKALASMYRVLKPGGRLLVLEFSTPLYEPLSKFYDFYSFNVLPKLGKLIANDSESYQYLAESIRMHPGQEILKEMMNSANFEGCEYFNLSGGIVALHRGYKY
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: RF3_LACDA
Sequence: MNKELLDKVNKRRTFAIISHPDAGKTTITEQMLLLGGVIRSAGTVKARKTGNYATSDWMEIEKKRGISVTSSVMQFEYQGKRINILDTPGHQDFSEDTYRTLMAVDAAVMVIDSARGIEPQTKKLFKVVRQRGIPVFTFMNKLDRDGREPLDLVAELEEVLGIEGVAMNWPIGMGQSLLGLYDLANQRVELYHPEEGQDRFIALADGKAPAGSPLADDPQFEETLGEIELLEGAGASFDRAKVLAGQQTPVFFGSALTNFGVETFLEQFVDLAPAPGEHEVNGDEELKPDDDEFSGFIFKIQANMNPQHRDRIAFVRVCSGEFSKGLDVTLARTGKQVRLNNAVEFESSARVQVSEAVAGDIVGLYDTGNFQIGDSVYAGKRKLEFPPLPEFTPELFMRVSPKNVMKQKSFHKGMNQLVQEGAVQLYRNYQTDDYILGAVGQLQFEVFQYRMKNEYNSEVEMTSIGHRVARWINPDQLDPKMSSSRNLLVKDRFGNPLFLFENAFAERWFHDKYPDVELTEKL
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX41A_ETHRU
Sequence: MTRHLIFAAVLLVCLFVCWNAIGAQDARSAFSSEETAQDQHVMEERIFINPAGNREKNACLENCRSSPNCKNYEFCSK
What are the official names of this protein?
U-scoloptoxin(04)-Er1a, U-SLPTX(04)-Er1a, U-scoloptoxin-Er1.1a2a, U-SLPTX-Er1.1a2a.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-04 family.
What are the subcellular locations of this protein?
Secreted. Note=The mature toxins are clearly liberated from the multidomain precursors in the venom gland prior to venom expulsion and not by venom proteases upon secretion.
Protein: VAPC9_MYCTU
Sequence: MIVVDASAALAALLNDGQARQLIAAERLHVPHLVDSEIASGLRRLAQRDRLGAADGRRALQTWRRLAVTRYPVVGLFERIWEIRANLSAYDASYVALAEALNCALVTADLRLSDTGQAQCPITVVPR
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  An RNase.  The cognate antitoxin is VapB9 (By similarity).
What are the official names of this protein?
Ribonuclease VapC9, RNase VapC9, Toxin VapC9.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: ENO_STAA9
Sequence: MPIITDVYAREVLDSRGNPTVEVEVLTESGAFGRALVPSGASTGEHEAVELRDGDKSRYLGKGVTKAVENVNEIIAPEIIEGEFSVLDQVSIDKMMIALDGTPNKGKLGANAILGVSIAVARAAADLLGQPLYKYLGGFNGKQLPVPMMNIVNGGSHSDAPIAFQEFMILPVGATTFKESLRWGTEIFHNLKSILSKRGLETAVGDEGGFAPKFEGTEDAVETIIQAIEAAGYKPGEEVFLGFDCASSEFYENGVYDYSKFEGEHGAKRTAAEQVDYLEQLVDKYPIITIEDGMDENDWDGWKQLTERIGDRVQLVGDDLFVTNTEILAKGIENGIGNSILIKVNQIGTLTETFDAIEMAQKAGYTAVVSHRSGETEDTTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDELFETAKYDGIKSFYNLDK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: END4_MYCMS
Sequence: MDKILLGCHVSMNKQNNYLVGSVNEAISYKANTFMIFTGPPQSTLRTNTNHLYINQMHELMNSYKIDAKDLVVHAPYIINIANSVDQNKWKFTVDFLIQEIKRCEEIKIPTLVLHPGSYTTGNYKDSLNQIIKALNIVSNYQVNVKIALETMSGKGTEVCSRLEDFKYILDNVKNKDKVGVCLDTCHLHDAGYDLSKWTEFKEQMKQNFSLDKVLCIHLNDSKNMISSHKDRHANIGYGYVGFDTLVNVVFDKDFSNISKILETPYIDKTPPYKIEIEDLLNKTFTNRL
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: CAPSD_PAVBP
Sequence: MPPTNKANSKKGLTLPGYNYLGPFNSLFAGAPVNKADAAARKHDFGYSDLLKEGKNPYLYFNTHDQNLIDELKDDTSFGGKLARGVFQIKKALAPALPGTSKGGDRALKRKLYFARSNKGAKKANREPAPSTSNQQNMEVSNDIPNDEAGNQPIELATRSVVGSGSVGGGGRGGSGVGYSTGGWTGGTIFSENIVVTKNTRQFICDIKNGHLYKSEVLNTGDTAHRQYAITTPWSYFNFNQYSSHFSPNDWQHLVNDYERFRPKAMIVRVYNLQIKQIMTDGAMGTVYNNDLTAGMHIFCDGDHRYPYVQHPWDDQCMPELPNSIWELPQYAYIPAPISVVDNNTTNTVEEHLLKGVPLYMLENSDHEVLRNGRIYRIYIQLWRLRMDRKQHHIQHASDDVQSTGQKQKNLLIQRTKQPNKQRFQNAALRTSNWMSGPGIARGTHNATLQTQSAGALVTMVTNGADVSGVRAVRVGYSTDPIYGGQQPESDLLRLRYSASAAEGQQNPILENAARHTFTREARTKLITGSNGADGDYKEWWMLPNQMWDSAPISRYNPIWVKVPRVNRKTLLDTQDGSIPMSHPPGTIFIKLARIPVPGNGDSFLNIYVTGQVSCEVVWEVEKRGTKNWRPEYMHSATNMSVDAYTINNAGVYAGAVQNADVMQTRFNHHKVL
What is the function of this protein?
Capsid proteins self-assembles to form an icosahedral capsid with a T=1 symmetry, about 26 nm in diameter, and consisting of 60 copies of three size variants of the capsid proteins, VP1, and VP3, which differ by the presence of an N-terminal extension in the minor protein VP1.  The capsid has a channel at the 5-fold axis and there are densities extending the 5-fold axis into the interior of the capsid.  The capsid encapsulates the genomic ssDNA (By similarity).  Binding to the host receptors also induces capsid rearrangements leading to surface exposure of VP1 N-terminus, specifically its phospholipase A2-like region.  The additional N-terminal region of isoform Minor capsid protein VP1, called VP1u, may serve as a lipolytic enzyme to breach the endosomal membrane during entry into host cell and might contribute to virus transport to the nucleus (By similarity).
What are the official names of this protein?
Minor capsid protein VP1.
What is the protein family that this protein belongs to?
Belongs to the parvoviridae capsid protein family.
What are the subcellular locations of this protein?
[Isoform Minor capsid protein VP1]: Virion. Host nucleus. Host cytoplasm. Note=Slightly detected in the cytoplasm, mainly seen in the nucleus. SUBCELLULAR LOCATION: [Isoform Minor capsid protein VP2]: Virion. SUBCELLULAR LOCATION: [Isoform Major capsid protein VP3]: Virion. Host nucleus. Host cytoplasm. Note=Slightly detected in the cytoplasm, mainly seen in the nucleus.
Protein: CUTC_YERPP
Sequence: MTKLEVCCYSVDCAQIAEKAGADRVELCCGQSEGGVTPSVGALMQARETVTIPVHPIVRPRGGDFCYSSNDFTIMKNDIARIRDLGFAGVVVGVLDTDGHIDMPRMREIMSVSGSLAVTFHRAFDMCQNPMIALKQLAELNVARILTSGQQQNAELGLALLKDLVAATKDQGPIIMAGAGVRLTNMQKFIDAGIRELHSSAGRTVPSTMRYRKAGVTMCADSDVDEFSHYCVDGEVVEAMKSLLVMGSPLAKHT
What are the official names of this protein?
PF03932 family protein CutC.
What is the protein family that this protein belongs to?
Belongs to the CutC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCH_METMJ
Sequence: MLSVNELALDIFEELFEYAEELHAVPHELDNGARIVDCGVSTSGGYLTGRRFTEICMGGLGEVDISMGKIRDFPIPFIEVSTDFPSIACLGAQKAGWTVNVNKYFAMGSGPARALSLKPKHTYEVIEYEDEFDYAVICLESDHLPNAAVMENIAEACNVDVANTCAVVAPTASLVGSIQVAGRCVETAVYKLNELGFDTKKITAGIGHAPIAPVKKDGTKAMGSTNDATIYHGSIMLTMNAPEIKDYLDKIPSNKSKGYGKPFYDIFKEANFDFYQIDTSLFSPAEVVINELSEGKVYHVGAVNPEVTLKSFGFI
What is the function of this protein?
Catalyzes the reversible interconversion of 5-formyl-H(4)MPT to methenyl-H(4)MPT(+).
What are the official names of this protein?
Methenyltetrahydromethanopterin cyclohydrolase, Methenyl-H4MPT cyclohydrolase.
What is the protein family that this protein belongs to?
Belongs to the MCH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBAS1_HUMAN
Sequence: MAQDFSQHPQTGIIRRHRFYSPKPLSTTPRGQSFLLSRQAKVATWDPMLSPDFQPKSAFKLTWTAQPPCLSVTPSQGQTFHPNSPEGELPPDLTENTCPSQA
What are the official names of this protein?
Putative uncharacterized protein encoded by RBM12B-AS1, RBM12B antisense RNA 1, RBM12B antisense gene protein 1.
Protein: COQ7_PSEFS
Sequence: MTTQRHYSPIDRLLLQADMAMRTLLPFSGQPYRPSPAIVQPDAQMSETETRHVAGLMRINHTGEVCAQALYQGQALTAKLPQVRAAMEHAAEEEIDHLAWCEQRIRQLGSHPSVLNPLFYGLSFGIGAAAGLISDKVSLGFVAATEHQVCKHLDEHLEQLPAEDEKSRAILEQMRIDEEHHAESALDAGGFRFPAPVRFGMSLLAKVMTKSTYRI
What is the function of this protein?
Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
What are the official names of this protein?
3-demethoxyubiquinol 3-hydroxylase, DMQ hydroxylase, 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the COQ7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PHF23_HUMAN
Sequence: MLEAMAEPSPEDPPPTLKPETQPPEKRRRTIEDFNKFCSFVLAYAGYIPPSKEESDWPASGSSSPLRGESAADSDGWDSAPSDLRTIQTFVKKAKSSKRRAAQAGPTQPGPPRSTFSRLQAPDSATLLEKMKLKDSLFDLDGPKVASPLSPTSLTHTSRPPAALTPVPLSQGDLSHPPRKKDRKNRKLGPGAGAGFGVLRRPRPTPGDGEKRSRIKKSKKRKLKKAERGDRLPPPGPPQAPPSDTDSEEEEEEEEEEEEEEMATVVGGEAPVPVLPTPPEAPRPPATVHPEGVPPADSESKEVGSTETSQDGDASSSEGEMRVMDEDIMVESGDDSWDLITCYCRKPFAGRPMIECSLCGTWIHLSCAKIKKTNVPDFFYCQKCKELRPEARRLGGPPKSGEP
What is the function of this protein?
Acts as a negative regulator of autophagy, through promoting ubiquitination and degradation of LRSAM1, an E3 ubiquitin ligase that promotes autophagy in response to starvation or infecting bacteria.
What are the official names of this protein?
PHD finger protein 23, PDH-containing protein JUNE-1.
What is the protein family that this protein belongs to?
Belongs to the PHF23 family.
Protein: TSAC_COXBN
Sequence: MDDYTQSINDAVKCLRQGGVIAYPTEAVYGLGCDPFNHDAVAQLLTIKKRSIKKGFILIASEWKQVEPLTEPIDPKALARVFDTWPGPFTWTFPASKEAPHWITGQHSTIAIRVTAHPLAKLLCQRFAGPLISSSANQEGGPPIRDVKILRLVFGNKIDKILEGPLGPTHRPTPIRDAITGEILRL
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: A30BL_HUMAN
Sequence: MERLSAAPVKGQTGPERPSPFSQLVYTNNDSYVIHHGDLRKIHKAASRGQAWKLERMMKKTTMDLNIRDAKKRTALYWACANGHAEVVTLLVDRKCQLDVLDGENRTILMKALQCQREACANILIDSGADPNIVDVYGNTAVHYAVNSENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEEIVEFLLTKNANANAVDKFKCVHQQLLEYKQKISKNSQNSNPEGTSEGTPDEAAPLAERTPDTAESLVERTPDE
What are the official names of this protein?
Putative ankyrin repeat domain-containing protein 30B-like.
Protein: RR8_NICTO
Sequence: MGRDTIAEIITSIRNADMDRKRVVRIASTNITENIVQILLREGFIENVRKHRENNKYFLVLTLRYRRNRKRPYRNILNLKRISRPGLRIYSNYQRIPRILGGMGIVILSTSRGIMTDREARLEGIGGEILCYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YCIB_RALSO
Sequence: MKFLFDLFPVILFFAAFKVAGIYVATTVAMVATVAQIAWVWFKHRKVDAMQWLSLLIIVVFGGATLIFHNDTFIKWKPTVLYWMFGVVLLGSAVLLRKNLIRAMMEQQVSLPEPMWGRLNLVWSLFFLAMGGLNLYVAYHFDTDVWVNFKLFGSMGLMVVFILVQSVWLARHMQERPAGANPQDDR
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SKP1_CAVPO
Sequence: MPSIKLQSSDGEIFEVDVEIAKQSVTIKTMLEDLGMDDEGDDDPVPLPNVNAAILKKVIQWCTHHKDDPPPPEDDENKEKRTDDIPVWDQEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMIKGKTPEEIRKTFNIKNDFTEEEEAQVRKENQWCEEK
What is the function of this protein?
Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription.  In the SCF complex, serves as an adapter that links the F-box protein to CUL1.  The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component.  SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and participate in Wnt signaling.  SCF(FBXW11) directs ubiquitination of phosphorylated NFKBIA.  SCF(BTRC) directs ubiquitination of NFKBIB, NFKBIE, ATF4, SMAD3, SMAD4, CDC25A, FBXO5, CEP68 and probably NFKB2.  SCF(SKP2) directs ubiquitination of phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition.  SCF(SKP2) directs ubiquitination of ORC1, CDT1, RBL2, ELF4, CDKN1A, RAG2, FOXO1A, and probably MYC and TAL1.  SCF(FBXW7) directs ubiquitination of cyclin E, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1.  SCF(FBXW2) directs ubiquitination of GCM1.  SCF(FBXO32) directs ubiquitination of MYOD1.  SCF(FBXO7) directs ubiquitination of BIRC2 and DLGAP5.  SCF(FBXO33) directs ubiquitination of YBX1.  SCF(FBXO11) directs ubiquitination of BCL6 and DTL but does not seem to direct ubiquitination of TP53.  SCF(BTRC) mediates the ubiquitination of NFKBIA at 'Lys-21' and 'Lys-22'; the degradation frees the associated NFKB1-RELA dimer to translocate into the nucleus and to activate transcription.  SCF(CCNF) directs ubiquitination of CCP110.  SCF(FBXL3) and SCF(FBXL21) direct ubiquitination of CRY1 and CRY2.  SCF(FBXO9) direct ubiquitination of TTI1 and TELO2.  SCF(FBXO10) direct ubiquitination of BCL2.
What are the official names of this protein?
S-phase kinase-associated protein 1, Cyclin-A/CDK2-associated protein p19, Organ of Corti protein 2, OCP-2, Organ of Corti protein II, OCP-II, S-phase kinase-associated protein 1A, p19A, p19skp1.
What is the protein family that this protein belongs to?
Belongs to the SKP1 family.
Protein: AZOR_NOSS1
Sequence: MANILHIDSSPRGDRSISRKLSYEFITSWKDTHPGDTVTYRDLGHNPVPHVDEPWIAAAFSSPESHTPELKTAIELSDTLIDEFLAADRLVFGVPMYNLNIPSTFKAYIDQIVRAGKTFTVDANGYKGLVDSSKKVLIITSRGGSYPPGTPYAAYDYQEPYLRAILGFMGLTDVTFIHAESLNMGEDAREKSLAGAKDAIAQAVANW
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: GCSH_MYCSS
Sequence: MSEIPAELYYTDEHEWVLRTGDDTLRVGITDYAQAALGDVVFVQLPDVGAELTSGESFGEVESTKSVSDLYAPVSAKVLAVNGNLEASPDLVNSDPYGEGWLVDLQLDADDMEAALGGLLDADGYRGVVTE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.