PharMolix/UniProtQA huggingface dataset:
Protein: MNTH_LACPL
Sequence: MKSAKTKDHAKMKAAEEKAIHSTGADSKSLDEVNGSVRVPKDASFWRTLIAYTGPGALVAVGYMDPGNWITSIAGGSQYKYALLSVILLSSLIAMLLQAMAARLGIVTGKDLAQLTRERTSKGMGIFLWIITELAIMATDVAEIIGSGIALKLLFGFPLIVGILITTADVLILLLLMKLGFRKIEAIVATLVAVILFVFLYEVIISQPNIPEMLKGYVPTSRIVSNRSMLFLALGIVGATVMPHNLYLGSSISQTRQVDRSDEKEVAKAVKFTTIDSNIQLSVAFVVNSLLLILGAALFFGTKGDLGRFVDLYNALGDSKVVGSIASPLLSMLFAIALLSSGQSSTITGTLSGQIIMEGFIRLKMPLWAQRLLTRLISVTPVLAFAIYYHGNEAKIEDLLTMSQVFLSIALPFAMIPLVMFTSNRALMGNFTNRVWVKWTAWIVTVILIILNIYLILQTVGLVK
What is the function of this protein?
H(+)-stimulated, divalent metal cation uptake system.
What are the official names of this protein?
Divalent metal cation transporter MntH.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RRF_MYCLB
Sequence: MIDEALFDAEEKMEKAVSVAREDLSMIRTGRANPGMFSRLVIDYYGSATPITQLASINVPEARLVVIKPYDAIQLHAIETAIRNSDLGVNPSNDGTLIRVAVPQLTEERRRELVKQAKCKGEDAKVSVRNIRRKVMEELHRIRKDGEAGEDEVSRAEKDLDKTTHQYVIQIDELVKHKEGELLEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PFKA_CLOB6
Sequence: MRTIAVLTSGGDAPGMNAAIRAVVRTGLEKGLKVMGIQRGYNGLINGEIFEMDTHSVSDIIQRGGTILRTARCEEFRTEQGREKAAKILKAFGIDGLVVIGGDGSFHGAQLLSKLGINTVGLPGTIDNDLAYTDYTIGFDTSINTVLDAINKLRDTSTSHERVSVVEVMGRNCGDIALYTGVAGGAESIIIPEKEYNADKLCKQILQGKLKGKMHNLVLLAEGVGGANELAKYIEEVTGIETRSTILGHIQRGGSPTCMDRILASRMAYKAVELLISGKSSRVVGIKNGEIIDMDIDEALAVERSFDQELYDIATILSK
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_MUSAL
Sequence: MTNIRKTHPLTKIINNSFIDLPAPSNISAWWNFGSLLGICLIIQILTGLFLAMHYTSDTATAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFLHVGRGLYYGSYMFSETWNIGIILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTSLVEWIWGGFSVDKATLTRFFAFHFILPFIISALAAVHLLFLHETGSNNPSGIPSDSDKIPFHPYYTIKDILGALFLILTLMLLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPAKLGGVLALVFSILVLAIIPLLHTSKQRSMTFRPLSQCLFWLLVADLLTLTWIGGQPVEHPFITIGQLASILYFMILLVLMPIISIIENNMLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RIMO_PARXL
Sequence: MSATPPIAPIATPKVGFVSLGCPKALVDSEQIITQLRAEGYEISGTYDGADLVVVNTCGFIDEAVQESLDAIGEALNENGKVIVTGCLGAKKSASGSGLIEEVHPKVLAVTGPHALGEVMQHVHMHLPKPHDPFVDLVPAAGVKLTPRHYAYLKISEGCNHRCTFCIIPSMRGDLVSRPVADVMLEAENLFKSGVKELLVISQDTSAYGVDVKYRTGFWNGKPIKTRMTDLVGALGELAAQYGAWVRLHYVYPYPSVDEVIPMMAEGPFKGHVLPYLDVPFQHAHPEVLKRMKRPANAEKVMERVKKWREMCPDLTIRSTFIAGFPGETEEQFQTLLDFIREAELDRVGCFAYSPVEGATANELDGALPDEVREERRARFMEVAEEVSAKRIAKKVGKTLKVLVDEINADGGIGRTAADAPEIDGVVYIAPAVKASKRYKVGDFVSVKITGADGHDLWGEV
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_SYNP2
Sequence: MATFEGTYNDNTQALKLAIVIGRFNDLVTSKLLAGCQDCLRRHGVNTDPEGAQIDYIWVPGCFEISLVAKKLADSGKYDAIICLGAVIRGDTPHFDYVAAEVSKGVAAAAFQTGVPVIFGVLTTDTMQQALERAGIKNNLGWGYALSALEMASLMGKI
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: UBIE_RHOPS
Sequence: MNQPGETTHFGFRDVPLNDKQTMVNDVFHSVASRYDLMNDLMSGGMHRLWKDVMITTLNPPRDDAPFRLLDVAGGTGDISFRAAKASGAGFQATVCDINTDMLEVGRQRAVQRHLDGQVDFVEGNAEALQFPDRSYDAYTIAFGIRNVPRIDLALKEAYRVLKPGSRFLCLEFSSVDVPGLNKIYDLFSFKVIPEIGRVVTGDAESYQYLVESIRKFPKPYDFAEMMRDAGFARVNWQMMSGGIVALHSGWRL
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: RBS_GLYTA
Sequence: MASSMISSPAVTTVNRAGAGTVAPFTGLKSMAGFPTRKTNNDIASIASNGGRVQCMQVWPTTGKKKFETLSYLPDLDDAQLAKEVEYLLRKGWIPCLEFELEHGFVYREHHRSPGYYDGRYWTMWKLPMFGCTDASQVLKELQEAKTAYPNAFIRIIGFDNVRQVQCISFIAYKPPSF
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, chloroplastic, RuBisCO small subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RNC_FRAT1
Sequence: MVPEYSRFYNILGYNFKDYTLLIRALTHRSKTKKNYERLEFLGDSVLSFVIAEVLYKQFIDLAEGKLSQLRSKLVKGATLAQLASSLKMDEYIILGASEQGGHKREKILEDVFEAVIGAIYLDSDFATVKKVILKWYQPIISSINLDTIKVKDSKSKLQEILLQNALSLPEYSIETIDGKDHEQQFTVVAVSKDLNLRVKAQGTSRKKAEQKTAEKMIEMLSQQGLHEKK
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MET_PANTR
Sequence: MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKYQLPNFTAETPIQNVILHEHHIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVWKDNINMALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSALGAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRFCSINSGLHSYMEMPLECILTEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSSCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNFLLDSHPVSPEVIVEHTLNQNGYTLVVTGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGWCHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIIISNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEFAVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKSCENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVSISIALLLLLGFFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSEDNADDEVDTRPASFWETS
What is the function of this protein?
Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand.  Regulates many physiological processes including proliferation, scattering, morphogenesis and survival.  Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules.  Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1.  Recruitment of these downstream effectors by MET leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC.  The RAS-ERK activation is associated with the morphogenetic effects while PI3K/AKT coordinates prosurvival effects.  During embryonic development, MET signaling plays a role in gastrulation, development and migration of muscles and neuronal precursors, angiogenesis and kidney formation.  In adults, participates in wound healing as well as organ regeneration and tissue remodeling.  Promotes also differentiation and proliferation of hematopoietic cells (By similarity).
What are the official names of this protein?
Hepatocyte growth factor receptor, HGF receptor, HGF/SF receptor, Proto-oncogene c-Met, Scatter factor receptor, SF receptor, Tyrosine-protein kinase Met.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: CLPP_YERPA
Sequence: MSYSGERDQFAPNMALVPMVVEQTSRGERSYDIFSRLLKERIIFLTGQVEDHMANLITAQMLFLEAENPEKDIFLYINSPGGVITAGMSIYDTMQFIKPDVSTICMGQACSMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGFQGQATDIEIHAKEILKVKSRMNELMAYHTGKSLEEIERDTERDRFLSAEQSVEYGLVDSVFTRRD
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBEAG_HBVB3
Sequence: MQLFHLCLIISCSCPTVQASKLCLGWL
What are the official names of this protein?
Truncated HBeAg protein.
Protein: NAHB_PSEPU
Sequence: MGNQQVVSITGAGSGIGLELVRSFKSAGYYVSALVRNEEQEALLCKEFKDALEIVVGDVRDHATNEKLIKQTIDRFGHLDCFIANAGIWDYMLSIEEPWEKISSSFDEIFDINVKSYFSGISAALPELKKTNGSVVMTASVSSHAVGGGGSCYIASKHAVLGMVKALAYELAPEVRVNAVSPGGTVTSLCGSASAGFDKMHMKDMPGIDDMIKGLTPLGFAAKPEDVVAPYLLLASRKQGKFITGTVISIDGGMALGRK
What is the function of this protein?
Catalyzes the oxidation of naphthalene dihydrodiol into 1,2-dihydroxynaphthalene.
What are the official names of this protein?
1,2-dihydroxy-1,2-dihydronaphthalene dehydrogenase, Cis-naphthalene dihydrodiol dehydrogenase, Dibenzothiophene dihydrodiol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: RPOA_TUPAK
Sequence: MIKIIIKETFSFKSVLMHFLKEKVSNNKISKKNKIMPSYTLLSCIDSRVENLTKFYGRFELGPFAPGQALTVANALRRSLLSQLPGTSITLVEVRGASNEYEIITGVRESILDILLNLKQIVLTSDFEIFSPQIGFLSVEGPGVIRANDLKLPSFIYAVDPNQYIATLSNSGRLNMKFLICCGKNYITYNPNDSQYFEWLSLLKKSKPLIKSNSPKLNKGNINSEIDSDISIDKKNDEVIFFQNANTRVVDSQTALKKGLVLKNTLRINKSSFLINSNYQSFFPKTQQKAFSIFRKNSKTFLSTMGFYKEWKKEREFLKKDLYKNQEDFNKSYDFQETKKKLQTKLIKNFETPKKKLFKVQNSANPFNKAFIPLTEEKVDYDSDFNLDHKSTKIGYFPIDAIFMPINRVNYLIESTEDIKLKIKDRVILEVWTNGSIHPRHAIHKAAKALIQLFLPLQQIRTNLFLISDNSHFEEGQDKIKKRIDNFKKEALLKANPQIQANPQLKKRNFDHRLLELDIANLELTARPYSCLKLANINTIEDLISYSQEDLLSIKNFGRRSLIEVQKALQLMKLTLK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TRPC_BRUAB
Sequence: MSTDILRKIEAYKREEIAAAKARLALDELKARTRDQSAPRGFLKALEAKRAAGQFALIAEIKKASPSKGLIRPDFDPPALAKAYEEGGAACLSVLTDTPSFQGAPEFLTAARQACSLPALRKDFLFDPYQVYEARSWGADCILIIMASVDDDLAKELEDTAFALGMDALIEVHDEAEMERALKLSSRLLGVNNRNLRSFEVNLAVSERLAKMAPSDRLLVGESGIFTHEDCLRLEKSGIGTFLIGESLMRQHDVAAATRALLTGAEKL
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: MAEL_AEDAE
Sequence: MPKKPAAKGPFFFFMLEFRRREESRGKSFPGGMDQVMREAGPHWNQLNEAEREVYKDRAKSYKELPKQNYGEKYTAQGIAFSQVEMEKQQLLKKHETIRKTISEMIQTAVLNNALEKLEVFFMSCNYFCKTSTEAFVPAEIALIKYNLELGVLDKLHELINPVRLPLGLAHEALTYSEQTHELPTPPNAMGETDFYTVLQKILSFTDYNSKPHKKLAIMTDAKEVPVIESLLSQLNDDVKLEYQFLVIPLGEFFFHLKRATEKYGLDICTFPTKTVADILLKKDAYEYTSGIACDFHEKLGNQRFCALSKVVRWSYIISDNCCLDLSIDLIAGRHLPSNADTTLCSDLYETTSKTNQSQSDGMSFVSSSELTHFTLPKIQKVQSKSAFRSVEDKNGSVIYSSRTVPKKDVKTETTEPHAPINPFYMVDGNDSVYAPSYPTKSNGTRPGTSYNPFSRQKKLDEVREPHGLDVKGKGRGTLLVTANNSFSSMLKGAGRGSGLFAGLSSVGSNSSVRLSDDEN
What is the function of this protein?
Plays a central role during gametogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity.  Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the repression of transposons (By similarity).
What are the official names of this protein?
Protein maelstrom homolog.
What is the protein family that this protein belongs to?
Belongs to the maelstrom family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis.
Protein: NU4M_OVOOK
Sequence: PIAGSMVLAAILLKLGGYGIIRMMQILPTTKTDLFLPFMVLALWGAILANLTCLQQTDLKSLIAYSSISHMGLVVAAIIIQTPWGLSGAMALMIAHGFTSSALFCLANTTYERTHTRILILTRGLHNILPMATTWWLLTNLMNIATPPTMNFTSELLIMSALFNWCPTTIIMLGLSMLITASYSLHMFLSTQMGSALTNNQTEPTHSREHLLITLHIIPLVMVSLKPELII
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: LCL3_PARBA
Sequence: MRWLFWSSGSQQAPNNKDNNNSNNNDDDDDDYDNNINKRPPLTPESPSPSHPPCASCSTQATASFSNPRRDWNTSLTAHDWAGEFKDPRNLIPTLLLTGGILFCVRIHRQYLRRIPLATNISPTYFHKRSLFGRVTSVGDGDNFRMYHTPGGRLAGWEWLPFRRVPRVKKELKDRTIHIRLAGIDAPELPHFGRPAQPYSHAAHTWLTNYLLNKRVRVFPYRQDQYGRVVATVYVRRFPWIFLRRDVGLQMLRAGMATVYEAKSGVEFGGEGKESKYRRAEEVAKRRGRGLWKGWKGVGWESPREYKNRMAGVEGEKAAAAAAAAAAAAAAAAGVGGMGELGVNGEKN
What are the official names of this protein?
Probable endonuclease LCL3.
What is the protein family that this protein belongs to?
Belongs to the LCL3 family.
What are the subcellular locations of this protein?
Mitochondrion. Membrane; Single- pass membrane protein.
Protein: KAD6_ARCFU
Sequence: MLIALTGTPGTGKSSVAERLRERGYKVATVVELAEKHGCIIDEEDGEIVIDVESLAARIDFEGIVEGHLSHLLKPDVAIVLRCNPAVLRERLKGRNWSEEKLLENLEAEMLDVILVEALEHASEVYEIDTTEMSLEEVIEAVEAIIRGDREARKRYKPGGIDWLSELEDRIEEFMRKV
What is the function of this protein?
Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.
What are the official names of this protein?
Putative adenylate kinase, AK, ATP-AMP transphosphorylase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family. AK6 subfamily.
Protein: BET5_NEOBT
Sequence: MKSFATTVLLVTPGIYAAALSGRQGQAINSSCKVIPGDTAWPSRQIWSQLNDTLDGRLIQSTPQAAVCRPGGYGSISENGTECTTLKEDWDYAKAFLDSAVEIMNPWYQNTSCSPFYRVDQPCTLGNYVSYAIPVSGPEDVVTAINFTQTHNVRLVIKNTGHDYLGKSTGTGGLSLWTHNLQSKQIVNYTSPAYSGPAIKVGAGVTGGEALLHASQFGYRLVSGDCSTVGYAGGYSSGGGHSLLNSVHGMAADNVLEWEVVTADGRHLVASATQNSDLYWALSGGGAGNLAVVLSMTAKVHPDGLVGAATLSFNATSSPSNTSYISAINAWWTFLPTLIDAGASPSFNIYTNNFLIYNTTAPGKSAQDMSTLYAPYLSTLSSLSIPYTFQTYTAPSFLQHYNATDGPLPYGPYVASQLFNSRMIPRSLSSSPSNLTTAILSSVATDAPGIWQLGCLGINVNSTRISHPDNAVAPHWRTAMAVCLEFSLYDWAIPEEEMVARRQHLADVIHPAIVKVTPGSGAYLNEADPLVYPVGEDGWKDAFYGANYERLRGLKREWDPERVFYAYTAPGSEEWVSDAEGRLCRV
What is the function of this protein?
FAD-linked oxidoreductase; part of the gene cluster that mediates the biosynthesis of betaenones, phytotoxic polyketides involved in leaf spot disease in sugar beets (PubMed:25530455).  The first step of the pathway is the synthesis of dehydroprobetaenone I by the polyketide synthase bet1 and the enoyl reductase bet3 via condensation of one acetyl-CoA starter unit with 7 malonyl-CoA units and 5 methylations (PubMed:25530455).  The C-terminal reductase (R) domain of bet1 catalyzes the reductive release of the polyketide chain (PubMed:25530455).  Because bet1 lacks a designated enoylreductase (ER) domain, the required activity is provided the enoyl reductase bet3 (PubMed:25530455).  The short-chain dehydrogenase/reductase bet4 then catalyzes reduction of dehydroprobetaenone I to probetaenone I (PubMed:25530455).  The cytochrome P450 monooxygenase bet2 catalyzes successive epoxidation, oxidation (resulting from epoxide opening) and hydroxylation to install a tertiary alcohol in the decaline ring to yield betaenone C from dehydroprobetaenone I and betaenone B from probetaenone I (PubMed:25530455).  The FAD-linked oxidoreductase (orf1) is probably responsible for the conversion of betaenone C to betaenone A via an intramolecular aldol reaction between C-1 and C-17 to form the bridged tricyclic system in betaenone A (By similarity).
What are the official names of this protein?
FAD-linked oxidoreductase orf1, Betaenone biosynthesis cluster protein B, FAD-dependent BBE enzyme-like protein.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
Protein: RL2_SOLUE
Sequence: MPIKSYRPTTPTRRFQTVVSREDITKQTPEKSLVESKKRSGGRNSTGRVTSRFIGGGAKKAYRVVDFKRDKAGIPAVVAAIEYDPNRSSRIALLNYVDGEKRYILQPDGLKVGMKIMSGPNADILIGNALPLKNIPAGTIVHNIELKPGKGGQMARSAGSQAQLVSREGGLALLKLPSGEIRRVAVECMATVGQVGNVDHENVSLGKAGRKRWMGKTPHNRGVSMNPVDHPHGGGEGKTSGGRHPVTPWGQPTRGFKTRNNKRTDKWIVNRKSKKR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: KDSA_ACIBC
Sequence: MSQLKPQEVVRLGDIQMANHLPFVLFGGMNVLESKDLAFEIAETYIDICKRLDIPYVFKASFDKANRSSLHSFRGPGLEKGIEWLGDIKKHFNVPIITDVHEPYQAAPVAEVADIIQLPAFLSRQTDLVEAMAKTQAIINIKKAQFLAPHEMRHILHKCLEAGNDKLILCERGSAFGYNNLVVDMLGFDIMKEMNVPVFFDVTHALQTPGGRSDSAGGRRAQITTLARAGMATGLAGLFLESHPDPDKAKCDGPSALRLSQLEPFLAQLKELDTLVKGFKKLDTH
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOI2_RHOP5
Sequence: MGVTTAARSLLLTEFVSAFFLAMRYFFKPKPTLNYPFEKGPISPRFRGEHALRRYPNGEERCIACKLCEAVCPAQAITIEAGPRRNDGTRRTERYDIDMVKCIYCGLCQEACPVDAIVEGPNFEFATETREELYYDKAKLLANGDRWEREIAKHMALDAPYR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I 2, NADH dehydrogenase I subunit I 2, NDH-1 subunit I 2.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RPOZ_ACTSZ
Sequence: MARVTVQDAVEKIGNRFDLILTAARRARQLQLNHREPLVPEDNDKPTVIALREIEKGLINNDIMDAQERQDALMQHQAEDAAVSLLTA
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: MENE_LISMF
Sequence: MTNWLQKRVRLSPKETALVFEGKEETFEEISEAVKQLAGKLFALGIRKDEMVALLGKNDRMTFLLIHALQQLGAVTLFLNNRLTKKEISFQLANAEVKHVIVADSLVDKVATGISYATLAETDYEAPALLETWDLSRAASVMYTSGTTGKPKGVVQTYENHWWSAVASVLNLGLTEKDSWLCAVPIFHISGLSIMMRSVIYGIPVYLEEHFDEEKITQLLESGKISTISVVTSMLERLLKIHSGSYHPNVRTVLLGGGPASKAVLEICKQRDIPLVQSFGMTETASQIVTLPPKDALNKIGSSGKALFPAEVKIADDGEILLKGPSITPGYLHNKKATEASFVDGWFKTGDIGYLDEEGFLFVLERRSDLIISGGENIYPTEIEHVISEYEGVKEVAVIGKPDDKWGSVPVAFIVAEETFDEAELRLICETNLAGYKIPKQITIVEKLPKTASGKIQRNKLKERHSM
What is the function of this protein?
Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).
What are the official names of this protein?
2-succinylbenzoate--CoA ligase, o-succinylbenzoyl-CoA synthetase, OSB-CoA synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.