PharMolix/UniProtQA huggingface dataset:
Protein: CR31_RANSP
Sequence: GLWQKIKDKASELVSGIVEGVK
What is the function of this protein?
Antibacterial peptide, that adopts an alpha helical conformation which can disrupt bacterial membranes.  Each caerin displays a different antimicrobial specificity.
What are the official names of this protein?
Caerin-3.1.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Caerin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ZEN_DROSU
Sequence: MSSVMHYYPVHHPTAPPVVKYSDLLYGHHHSANLQPTSLQNYTQHSVSSIPEHPSLQQHHHQHHQQQQLSSDENLPSQPSQDMQRVKLKRSRTAFTSVQLVELENEFKSNMYLYRTRRIEIAQRLSLCERQVKIWFQNRRMKFKKDIQGHREAKASAKLAQPQAEQSAHRGIVQRLMSYSQDPREAAASAAEKRPAVAAAPAAPVVAAPPVVAAATSTASFYGQAKIKPQAIPSNNNNSMCSSDLSEILEHLAQSTAXPAATVTPPGPSIGPTCGSTGVSSSGHYSYNVDLVLQSIKQDLEAAAQAWSKSKAGPVLANAQSWHPSGVGSSSVPAVSHATPSMNLSWGEPAAKSRKLSISHINPCVAGGYNYQN
What is the function of this protein?
Required for the differentiation of the dorsal-ventral pattern, and does not appear to be involved in the process of segmentation.
What are the official names of this protein?
Protein zerknuellt.
What are the subcellular locations of this protein?
Nucleus.
Protein: DAPE_CAMJR
Sequence: MNAKEFLIELLKFKSVTPNDDGALNFIAMELSDFEAFFIEKEGIKNLLLTKKFKDEGEHLAFGGHVDVVPAGEGWSSDAFVPMEKEGFIYARGAQDMKSGVAAFVDAVKNADFKGARLSLILTSDEEGEAIYGTKAVLEWMQERDMLPDYAVVAEPTCVKKIGDSIKIGRRGSINGKLLIRGKQGHAAYPEKCINPVHDFAPVLKLLAGFDLDPGSAEFSPSKIVITDIRGGMGVCNVTPNDLKLMFNVRNSPDTSLEDVKSYVEKICHGLNYELELKQSSEAFLTNIDNKIVQKMNESVQKITHEVPELNTKGGTSDARYFAKYGVKVVEFGVCNDRIHAIDERVSIEEFEKLCLVFKDLIENF
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: KS6A6_DANRE
Sequence: MISFGPAQESSLKMEVQSVSSEVNGHQIMDEPMEEESYTHCDEGAYKEIPITHHVKEGCEKADPSQFELLKVLGQGSFGKVFLVRKLMGPDAGQLYAMKVLKKASLKVRDRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVMFTEEDVKFYLAELALALDHLHNLGIVYRDLKPENILLDEAGHIKLTDFGLSKESVDQDKKAYSFCGTVEYMAPEVVNRRGHTQSADWWSLGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSLEAQGLLRMLFKRNPSNRLGAGPDGVEEIKRHTFFSTIDWNKLYRRELQPPFKPASGKPDDTFCFDPEFTAKTPKDSPGIPPSANAHQLFKGFSFVAPVSLEESKSAPLVNILPIVQVHGSSAQFSDVYELKEDIGVGSYSICKRCIHRVTAMEFAVKIIDKSKRDPSEEIEILMRYGQHPNIITLKDVYDEGRFVYLVTELMKGGELLDKILRQKFFSEREASAVLYTITKTVDYLHCQGVVHRDLKPSNILYMDDSGNPDSIRICDFGFAKQLRGDNGLLLTPCYTANFVAPEVLMRQGYDAACDIWSLGVLLYTMLAGYTPFANGPNDTPEEILLRIGSGKFSLSGGNWDSVSDSSKDLLSHMLHVDPHHRYTAEQVLKHSWIACRDQNPHFQLTRHEAPHLVKGAMAATYSALNHKTCKPVLEPVAASSLAQRRNMKKLTSTDMS
What is the function of this protein?
Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.
What are the official names of this protein?
Ribosomal protein S6 kinase alpha-6, S6K-alpha-6, S6K-alpha 6-like.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
Protein: DPS_SALEP
Sequence: MSTAKLVKTKASNLLYTRNDVSESDKKATVELLNRQVIQFIDLSLITKQAHWNMRGANFIAVHEMLDGFRTALTDHLDTMAERAVQLGGVALGTTQVINSKTPLKSYPLDIHNVQDHLKELADRYAVVANDVRKAIGEAKDEDTADIFTAASRDLDKFLWFIESNIE
What is the function of this protein?
During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages.  It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction.  One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.
What are the official names of this protein?
DNA protection during starvation protein.
What is the protein family that this protein belongs to?
Belongs to the Dps family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ST2B1_RAT
Sequence: MDGPQPPALWGSLENRVSELSQKLQGEYFRYKGIPFPVGMYTPESLSLAENTSNVRDDDIFIVTYPKSGTNWMIEIICLILKDGDPSWIRSEPIWQRAPWCETTISAFSLPERPSPRLMCSHLPIELFTKAAFSSKAKVIYLGRNPRDVVVSLYYYSKIAVQLKDPGTPEQFLQNFLKGEVQFGSWFDHIKGWIRMRGRENFLFITYEELQQDLRGSVQLICEFLGRPLGEEALSSVVAHSAFAAMKANNMSNYTLLPASLLDHRQGAFLRKGISGDWKNHFTVAQSETFDQVYREQMHGLPSFPWDRSAEDGSPDGETEPSPSPSPGLASDDPNPGSSQ
What is the function of this protein?
Prefers pregnenolone over DHEA as a substrate and does not sulfate cholesterol.
What are the official names of this protein?
Sulfotransferase 2B1, Alcohol sulfotransferase, Hydroxysteroid sulfotransferase 2, Sulfotransferase family cytosolic 2B member 1, ST2B1.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Microsome. Nucleus.
Protein: VKT40_CYRSC
Sequence: MGIARILSAVLFLSVLFVVTFPTLLSADHHDGRIDTCRLPSDRGRCKASFERWYFNGTTCTKFVYGGYGGNDNRFPTEKACMKRCAKA
What is the function of this protein?
Dual-function toxin that inhibits both serine proteases and voltage-gated potassium channels (Kv).
What are the official names of this protein?
Kunitz-type kappaPI-theraphotoxin-Hs1d, KappaPI-TRTX-Hs1d, Huwentoxin HW11c40, Kunitz-type serine protease inhibitor HWTX-XI-IS40.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family. 01 (intermediate) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: KTHY_ERWT9
Sequence: MNSKFIVIEGLEGAGKTTAREAVVSELQRHGINDIIFTREPGGTPLAEKLRELIKQGVEGERVTDSAELLMLYAARVQLVENVIKPALARGAWVVGDRHDLSSQAYQGGGRGMDAGLMNSLKQAVLGDFAPDLTLYLDVTPQIGLQRARARGELDRIEQESLNFFTRTRERYLALASADSRIKTVDATRPLEQVTAALQQTLTQWLQEQR
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: TRI27_HUMAN
Sequence: MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETFPQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPCVLGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYGKEYWALTSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLSYSGGKSAAPLIICPMSGIDGFSGHVGNHGHSMETSP
What is the function of this protein?
(Microbial infection) Positively regulates hepatitis C virus replication by suppressing type I IFN response during infection.
What are the official names of this protein?
Zinc finger protein RFP, RING finger protein 76, RING-type E3 ubiquitin transferase TRIM27, Ret finger protein, Tripartite motif-containing protein 27.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Nucleus, PML body. Early endosome. Note=Nuclear or cytoplasmic depending on the cell type (By similarity). Colocalized with PML and EIF3S6 in nuclear bodies. Recruited to retromer-containing endosomes via interaction with MAGEL2 (PubMed:23452853).
Protein: FRDD_ALISL
Sequence: MVNLNPKRSDEPVWWGLFGAGGTWFAMLTPVTILVLGILVPLGVIGPESMNYLRVAGFVTSIIGALFVIGSISMPMWHAMHRVHHGMHDLKFHTGTAGKIACYATAALATVLSIVFIFMI
What is the function of this protein?
Anchors the catalytic components of the fumarate reductase complex to the cell membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit D, Quinol-fumarate reductase subunit D, QFR subunit D.
What is the protein family that this protein belongs to?
Belongs to the FrdD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CH60_DESOH
Sequence: MAGKEIKYSTKAREAMLAGVRTLADAVAVTLGPRGRNVVIEKSWGSPTVTKDGVTVAKEIELEDKFENMGAQMVKEVASKTSDTAGDGTTTATVLARAIYEEGQKLVAAGNNPMAIKRGIDKACEVAVKELAGMSKPTKNQREIAQVGTISANSDETIGNIIAEAMEKVGKEGVITVEEAKSMDTTLDVVEGMQFDRGYLSPYFVTDAEKMVVSLENAYILINEKKLSNMKELLPILEQTAKAGRPLLIIAEDIEGEALATLVVNKLRGTLNVAAVKAPGFGDRRKAMLEDIATLTGGQVVSEDVGINLEGITLGDLGHAKRITIDKDNTTIVDGAGKKADIEGRVKQIRAQIEDTTSDYDREKLQERLAKLVGGVAVINVGAATETEMKEKKARVEDALNATRAAVEEGVLPGGGVALVRCLDALSKIKIKSEEKLGVKVVMRAIEEPLRRIANNAGVEGSVVIEKVKNETGSFGYNAATGDYGDLIAAGVIDPTKVVRFALQNACSVASVMLTTEAMIAEKPSKEEPAAMPGGGMGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_PROMS
Sequence: MPNSIFKKQLSPIKPGDPIDYKDVELLKKFITERGKILPRRMTGLTSKQQRDLTLAVKRARIVALLPFVNPEG
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: COXX_BURMA
Sequence: MDTTLSHTPGSRLSQYLALTKPRVTQLAVFCAVIGMFLATPGMVPWKVLLGGTIGIGLLAGSAFAINCLVEQKIDAMMRRTAWRPSARGEITTLQILAFSTVLGGLGAWTLYTFTNPLTIWLTIATFVGYAVIYTLLLKPMTPQNIVIGGASGAMPPALGWAAVTGAVPGDAWILVLIIFVWTPPHFWVLALYRRKDYENAGLPMLPVTHGEQFTRLHILLYTVILFAVTMMPFISGMSGAVYLTSAVLLGALFLAYAWKIYRDYSDALARRAFRYSIVYLSLLFAALLVDHYARPVIGM
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYK_HAHCH
Sequence: MTENQNPAIDENKLIAERRGKLGKLREKGLAFPNDFRRDSYCADLQARYGDKSKEELEEASVRAKVSGRIMAMRGPFVVIQDMTGRIQLYIDRKGLPPEQLENVKLWDLGDIVAAEGALHKSDKGDLYVNMENPRLMVKALRPLPDKHKGLTNTEMRYRQRYLDLITNEEARETFRIRSKVIESIRYFLTKRDFIEAETPMLQVIPGGATARPFVTYHNALDIEMFLRIAPELYLKRLVVGGFERVFEINRNFRNEGLSTRHNPEFTMIEFYQAFADYKDLMNLTEEMLRWVAQEALGTTEVRNTSKNTDGDVVDEIIYDFGKPFIRMTVVESILHFNPELTLGDIDNMDGAKKVATGLGIPLKASWGLGKIQIEIFEKTVEHRLMQPTFITEYPTEVSPLARRNDDNPFVTDRFEFFVGGREIANGFSELNDPEDQAERFRKQVAEKEAGDDEAMFFDEDYITALEHGMPPTAGEGIGIDRLVMLLTDSPSIRDVILFPHMRPLAD
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_LIMRJ
Sequence: MGIRKYKATTNGRRNMNGYDFAEITKTTPEKSLLAPLKHTAGRNSYGHITVRHRGGGTKRQYRIIDFKRIKDDVPATVKAIEYDPNRTANIALLVYADGTKSYIIAPKGLKVGMTVQSGPDADIKVGNALPLKNIPVGTVIHNIELKPGKGGQLARSAGASAQLLGKEEKYVLVRLSSGEVRMVLATCRATIGTVGNDEHALIIKGKAGRTRYAGQRPHVRGSVMNPNDHPHGGGEGKQPVGLPSPLSPWGKKTVGKKTRSHKARSNKFIVRGRKRGPHTR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: SSB_CHLCV
Sequence: MMFGYFVGYLGADPEERMTSKGKRVVVLRLGVKSRIGTKDETVWCKCNVWHNRYDKMLPYLKKGSGVIVAGDISVESYMSKDGTPQSSLVISVDTIKFSPFGRNESRSLSLLEESSAQTTSYDNVSLGFEGESLDAEAIADKDMYAGYGQGQQYVSEDVPF
What are the official names of this protein?
Single-stranded DNA-binding protein, SSB.
Protein: DOCK1_HUMAN
Sequence: MTRWVPTKREEKYGVAFYNYDARGADELSLQIGDTVHILETYEGWYRGYTLRKKSKKGIFPASYIHLKEAIVEGKGQHETVIPGDLPLIQEVTTTLREWSTIWRQLYVQDNREMFRSVRHMIYDLIEWRSQILSGTLPQDELKELKKKVTAKIDYGNRILDLDLVVRDEDGNILDPELTSTISLFRAHEIASKQVEERLQEEKSQKQNIDINRQAKFAATPSLALFVNLKNVVCKIGEDAEVLMSLYDPVESKFISENYLVRWSSSGLPKDIDRLHNLRAVFTDLGSKDLKREKISFVCQIVRVGRMELRDNNTRKLTSGLRRPFGVAVMDVTDIINGKVDDEDKQHFIPFQPVAGENDFLQTVINKVIAAKEVNHKGQGLWVTLKLLPGDIHQIRKEFPHLVDRTTAVARKTGFPEIIMPGDVRNDIYVTLVQGDFDKGSKTTAKNVEVTVSVYDEDGKRLEHVIFPGAGDEAISEYKSVIYYQVKQPRWFETVKVAIPIEDVNRSHLRFTFRHRSSQDSKDKSEKIFALAFVKLMRYDGTTLRDGEHDLIVYKAEAKKLEDAATYLSLPSTKAELEEKGHSATGKSMQSLGSCTISKDSFQISTLVCSTKLTQNVDLLGLLKWRSNTSLLQQNLRQLMKVDGGEVVKFLQDTLDALFNIMMENSESETFDTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLKNYVDGAEKPGVNEQLYKAMKALESIFKFIVRSRILFNQLYENKGEADFVESLLQLFRSINDMMSSMSDQTVRVKGAALKYLPTIVNDVKLVFDPKELSKMFTEFILNVPMGLLTIQKLYCLIEIVHSDLFTQHDCREILLPMMTDQLKYHLERQEDLEACCQLLSHILEVLYRKDVGPTQRHVQIIMEKLLRTVNRTVISMGRDSELIGNFVACMTAILRQMEDYHYAHLIKTFGKMRTDVVDFLMETFIMFKNLIGKNVYPFDWVIMNMVQNKVFLRAINQYADMLNKKFLDQANFELQLWNNYFHLAVAFLTQESLQLENFSSAKRAKILNKYGDMRRQIGFEIRDMWYNLGQHKIKFIPEMVGPILEMTLIPETELRKATIPIFFDMMQCEFHSTRSFQMFENEIITKLDHEVEGGRGDEQYKVLFDKILLEHCRKHKYLAKTGETFVKLVVRLMERLLDYRTIMHDENKENRMSCTVNVLNFYKEIEREEMYIRYLYKLCDLHKECDNYTEAAYTLLLHAKLLKWSEDVCVAHLTQRDGYQATTQGQLKEQLYQEIIHYFDKGKMWEEAIALGKELAEQYENEMFDYEQLSELLKKQAQFYENIVKVIRPKPDYFAVGYYGQGFPTFLRGKVFIYRGKEYERREDFEARLLTQFPNAEKMKTTSPPGDDIKNSPGQYIQCFTVKPKLDLPPKFHRPVSEQIVSFYRVNEVQRFEYSRPIRKGEKNPDNEFANMWIERTIYTTAYKLPGILRWFEVKSVFMVEISPLENAIETMQLTNDKINSMVQQHLDDPSLPINPLSMLLNGIVDPAVMGGFANYEKAFFTDRYLQEHPEAHEKIEKLKDLIAWQIPFLAEGIRIHGDKVTEALRPFHERMEACFKQLKEKVEKEYGVRIMPSSLDDRRGSRPRSMVRSFTMPSSSRPLSVASVSSLSSDSTPSRPGSDGFALEPLLPKKMHSRSQDKLDKDDLEKEKKDKKKEKRNSKHQEIFEKEFKPTDISLQQSEAVILSETISPLRPQRPKSQVMNVIGSERRFSVSPSSPSSQQTPPPVTPRAKLSFSMQSSLELNGMTGADVADVPPPLPLKGSVADYGNLMENQDLLGSPTPPPPPPHQRHLPPPLPSKTPPPPPPKTTRKQASVDSGIVQ
What is the function of this protein?
Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility.  Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen (PubMed:19004829).  Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP.  Its GEF activity may be enhanced by ELMO1 (PubMed:8657152).
What are the official names of this protein?
Dedicator of cytokinesis protein 1, 180 kDa protein downstream of CRK, DOCK180.
What is the protein family that this protein belongs to?
Belongs to the DOCK family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane. Note=Recruited to membranes via its interaction with phosphatidylinositol 3,4,5-trisphosphate.
Protein: KATG1_MYCVP
Sequence: MTDTSDARPPHSDDKTRSHSESENPAIDSPEPKVHAPLTNKDWWPEQVDVSVLHKQNEKGNPLGEDFDYATEFAKLDVEAFKRDVIDLINTSQDWWPADYGSYAGLFIRMSWHAAGTYRIFDGRGGAGQGSQRFAPLNSWPDNANLDKARRLLWPIKRKYGNKISWADLIAYAGNAALESAGFQTFGFAFGREDIWEPEEMLWGQEDTWLGTDKRYGGTNDSDTRELAEPFGATTMGLIYVNPEGPEGKPDPLAAAHDIRETFGRMAMNDEETAALIVGGHTLGKTHGAADVNVGPEPEGAPIEQQGLGWKCPFGTGNAGDTVTSGLEVVWTTTPTKWSNAYLELLYGYEWELTKSPGGAWQFEAKDAEAIIPDPFGGPPRKPTMLVTDVSMRVDPIYGPITRRWLDHPEEMNEAFAKAWYKLMHRDMGPVSRYLGPWVAEPQLWQDPVPAVDHELIDESDIAALKAAVLQSGLSVPQLVKTAWASASSFRGTDKRGGANGARLRLEPQRSWEANEPSELDKVLPVLERIQQDFNASATGGKKVSLADLIVLAGSAAVEKAAKDGGYEISVHFAPGRTDASQEQTDVDSFAVLEPRADGFRNFARPGEKTPLEQLLVDKAYFLDLTAPEMTALIGGLRTLNANHGGSKHGVFTERPGVLSNDFFVNLLDMGTEWKPSELTENVYDGKDRATGQPKWTATAADLVFGSNSVLRAVVEVYAQDDNQGKFVEDFVAAWVKVMNNDRFDLG
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase 1, CP 1, Peroxidase/catalase 1.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: RUVC_ACICJ
Sequence: MPIRARIIGIDPGLRFTGFGIIEADGNRLRHVADGVIATDGAAAVAERLHTLDAALARLLATYAPDHAAVEETYVNRNATATLKLGYARGVALLAPARAGIAVAEYGAKTVKRAVVGTGAAEKDQVALMVRRLLPGAAITRADAADALAVAICHAHHLATASRVPAA
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: SYE1_LEVBA
Sequence: MSENSTVKKNVRVRYAPSPTGFLHIGNAQSALFNYLFARHYHGTMVLRIEDTDVKRNVPHGEDSQIDNLHWLGIDWDEGPDKPNPKYAPYHQTERQDLYHRYITQLLDQGLAYKDYATEDELTTMRDQQRAAGEAPHYDGRWYGRSVADQQAAEARGLKPSIRLHLPANHEYAWDDIIKGHVAFNSDNMGGDFIIEKSNGMPTYNFAVVIDDYLMDITDVLRGDDHIANTPKQIAVYEALGLKHPNFGHITLIYNPKTRKKLSKRDKETLQFISQYKNQGYLSEAIFNFIAFLGWSPEGEDELFSREELIERYDPARMSKSPAYFDQSKLDWINAAYIKRLDLDDMTDRVLELVDEGQTDVARQVKALQLPDLRTLTSQVCKIYQTEIHQLSEIMDKVLFYVTILQEPLDYDQLRQFDRTATLAVLTAFRKHVQALPVDVATPDFKKMIQTVSQETGVTGRNLYFPLNVAFTGDHSAPQIDEVLRLFANSTIIELLTKAIAHV
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 1, Glutamyl-tRNA synthetase 1, GluRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTXBC_STAA3
Sequence: MTKEQQLAERIIAAVGGMDNIDSVMNCMTRVRIKVLDENKVDDQELRHIDGVMGVIHDERIQVVVGPGTVNKVANHMAELSGVKLGDPIPHHHNDSEKMDYKSYAADKAKANKEAHKAKQKNGKLNKVLKSIANIFIPLIPAFIGAGLIGGIAAVLSNLMVAGYISGAWITQLITVFNVIKDGMLAYLAIFTGINAAKEFGATPGLGGVIGGTTLLTGIAGKNILMNVFTGEPLQPGQGGIIGVIFAVWILSIVEKRLHKIVPNAIDIIVTPTIALLIVGLLTIFIFMPLAGFVSDSLVSVVNGIISIGGVFSGFIIGASFLPLVMLGLHHIFTPIHIEMINQSGATYLLPIAAMAGAGQVGAALALWVRCKRNTTLRNTLKGALPVGFLGIGEPLIYGVTLPLGRPFLTACIGGGIGGAVIGGIGHIGAKAIGPSGVSLLPLISDNMYLGYIAGLLAAYAGGFVCTYLFGTTKAMRQTDLLGD
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  This system is involved in the uptake and phosphorylation of MurNAc-GlcNAc, the principle peptidoglycan turnover product of S. aureus, yielding cytoplasmic MurNAc 6P-GlcNAc.
What are the official names of this protein?
PTS system MurNAc-GlcNAc-specific EIIBC component.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS3_STAAE
Sequence: MGQKINPIGLRVGIIRDWEAKWYAEKDFASLLHEDLKIRKFIDNELKEASVSHVEIERAANRINIAIHTGKPGMVIGKGGSEIEKLRNKLNALTDKKVHINVIEIKKVDLDARLVAENIARQLENRASFRRVQKQAITRAMKLGAKGIKTQVSGRLGGADIARAEQYSEGTVPLHTLRADIDYAHAEADTTYGKLGVKVWIYRGEVLPTKNTSGGGK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: DAPA_THEYD
Sequence: MFKGSMVAIVTPFKKGKIDEKAFEKLIEWHIKEGTHGIVPCGTTGEASTLDYEEHYKVIEITVKVVNKRIPVIAGTGSNSTDEAIMITKKAEKLGADAALLVTPYYNKPTQEGLYRHYKEIADKTGIPLILYNVPGRTSVNILPQTVARLAEHPRIVGIKEATGDMKQVSELIRLCGDKITVLSGDDFTNLTLLALGGKGAISVTANICPKDMAELFNAWEKGDIEHARKLHYKLEPLNKAMFIETNPIPVKTALAMMGKIKEEFRLPLCEMSQTNKEKLAEVLRSAGLIK
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIR1_EHV4
Sequence: MALDFLSTDCPLGIVSDIISNVNTIKEYGYSSELSTTLAPRPSREQVLEYITRVVDKLKPLCRVDERLYIACGELVHLRIKARNTDLKYWLKSSEIDLSDVVEQAILEHIDFVQKTLNSFETSEYRDLCSLGLQSALKYEEMYLAKMRGGRLESMGQFFLRLATTATHYTMEQPAMARVLVSGEVGWTYIFRAFFTALAGQVVIPATPIMLFGGRDCGSMASCYLLNPRVTDMNSAIPALMEEVGPILCNRGGIGLSLQRFNTPPTEGCSRGVMALLKLLDSMTMAINSDGERPTGVCVYFEPWHADIRAILNMRGMLARDETVRCDNIFACMWTPDLFFDRYQRYVDGESGIMWTLFDDTASHLCHMYGNDFTREYERLERCGFGIDAIPIQDMAFIIVRSAVMTGSPFLMFKDACNRHYHFDMRQRGAIMGSNLCTEIIQHADETQNGVCNLASINLPKCLALPPPNIAGVPYFDFAALGRAAATATIFVNAMMCASTYPTVKSQKGVEENRSLGLGIQGLHTTFLMLDLDMASPEAHQLNKQIAERLLLNSMKASATLCKLGMQPFKGFEDSKYSRGELPFDAYPNVTLTNRNAWRRLRTDIKQYGLYNSQFVAYMPTVSSSQVTESSEGFSPVYTNLFSKVTATGEVLRPNVLLMRTIRSIFPQECARLQALSTLEAAKWSVVGAFGDLPVGHPLSKFKTAFEYDQTMLINMCADRAAFVDQSQSMSLFITEPADGKLPASRIMNLLVHAYKRGLKTGMYYCKIKKATNNGVFVGGDLVCTSCSL
What is the function of this protein?
Ribonucleoside-diphosphate reductase holoenzyme provides the precursors necessary for viral DNA synthesis.  Allows virus growth in non-dividing cells, as well as reactivation from latency in infected hosts.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
What are the official names of this protein?
Ribonucleoside-diphosphate reductase large subunit, R1, Ribonucleotide reductase large subunit.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase large chain family.
Protein: YIDD_CLOB8
Sequence: MKKLLIRLIKFYRKYISPGRSSCCRFVPTCSQYAIDAINKYGAFKGSALAVYRILRCNPFCKGGYDPVR
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS3_ECOHS
Sequence: MGQKVHPNGIRLGIVKPWNSTWFANTKEFADNLDSDFKVRQYLTKELAKASVSRIVIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAGVPAQINIAEVRKPELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRLGAKGIKVEVSGRLGGAEIARTEWYREGRVPLHTLRADIDYNTSEAHTTYGVIGVKVWIFKGEILGGMAAVEQPEKPAAQPKKQQRKGRK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.