PharMolix/UniProtQA huggingface dataset:
Protein: CRGA_CORGB
Sequence: MPKARVTKNETAPVSSNPSANRTPVKINSAGTPMWYKVIMFAFMIVGLAWLIVNYLVGPQIPFMADLGAWNYGIGFGLMIIGLLMTMGWR
What is the function of this protein?
Involved in cell division.
What are the official names of this protein?
Cell division protein CrgA.
What is the protein family that this protein belongs to?
Belongs to the CrgA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRPA_CAUVN
Sequence: MTKDRIDRRFAALKAENRAGFVTYVMAGDPDAATTLSVLKGLPAAGADLIELGFPFSDPMAEGPTIQRAAQRGLKSGMTLQGTLDLVAAFREGDQDTPIILMGYLNPVLNKGFETFAALAAKAGVDGLIIVDCPPEEADPLSDALEAEGIALIRLAAPTTDDARLPMVVRRTSGFVYYVSVAGVTGVKSADAADVAPAVERLRKASGLPVAVGFGIRTPDQAAAVAKVADAAVVGSALVDEIESAAQLNENVTEKVLLKASELAKAVRSARVGTK
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: SELD_RHIME
Sequence: MNTLAPRLTDLAHGGGCGCKLAPSVLQQLLANQPAARPFAQLLVGNDMADDAAVWQVDDNTCVIATTDFFMPIVDDPRDFGRIAATNAISDVYAMGGKPILALAIVGMPINKLDSTTIAKILEGGASICAEAGIPVAGGHSIDSVEPIYGLAVIGLCHPSEVRRNGGVKAGDALILTKGIGVGIYSAAIKKNALPPGCYEEMIGSTTLLNRIGADLAADPDVHALTDVTGFGVLGHGLEMARASQLSLTLRLSAIPFLSQAYMLAEQGFITGASGRNWASYGADVVLPDDLPDWQRLLLADPQTSGGLLVACAPEKAGALVEKVRLAGYPLAGIVGTAAAGAAQIKVIS
What is the function of this protein?
Synthesizes selenophosphate from selenide and ATP.
What are the official names of this protein?
Selenide, water dikinase, Selenium donor protein, Selenophosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the selenophosphate synthase 1 family. Class I subfamily.
Protein: VIE2_NPVOP
Sequence: MSRSNNANAPTPSNRRRNLSLVRGRRLTYSPPDAASAQRASPPRSAPRAAPRRVHAVGDPGAPLRASYALPNGVYNLHGDAHFNPPEEDDDILFVDTAAEQARQRAVNLHEAVNRHERLRRELGERMTRSPTLLNYSPSYSPTSPRSRSPDLIMPEDLQPAREQPLAPFNDSDDDERLLEQVMLESAEAPQLPQAPPAPQVDVSVLCHICSCTFTDIQNYNSNFVTSTECNHAVCFKCYVSIVFGKESYKCSICNRTTISCRAYNRDGYVELSTMSTVRDSQAIKRHWAQLSDSNMPHSNEMTTIQELQAELAELRAATARAHHDVNMARSDSQLLRQQLDVKEAELAHESNARLKLQKQNETLSANNLSLQHQLNTQVIESRVKMEQFKRQHDEFMEKFKLSLS
What is the function of this protein?
RING-finger E3 ubiquitin ligase that plays an important regulatory role during the initial stages of infection.  Migrates to specific nuclear foci early in infection supposely to prepare the sites for viral replication by targeting and ubiquitinating host proteins.
What are the official names of this protein?
E3 ubiquitin-protein ligase IE2, Immediate-early protein IE2, RING-type E3 ubiquitin transferase IE2.
What is the protein family that this protein belongs to?
Belongs to the alphabaculovirus IE2 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: MPS2_YEAS2
Sequence: MSNGAFDAIFEYAWGQIDKPISGDFIYGKDLPKLIEIIENIFQKAQKSGSYELRLPLFSEINKDLFRTFSNTKTFFKIHKEEFDDIFFNLVNHPLREILENAFIGVDSIPSDFIVSMNLNSPSKFLVENKSKNTEGAGISTPRKKLTESPIKLLSRNNIGKALEVQVEELKRELTAKQSLLQENERQVSELKIRLETYQEKYASIQQRFSDLQKARQVEDNQNSSRTSDPGSPLVTGIDQKAILEEFRRRLQRQTDTISFLKDQIRRERGLNCSNDKVSHSKRKHATTDGDGTFKNFISAVPSNIWVKATIRIIVCFALLAGVLPYIRKYVYAHDTPSQNSRLQLSWWENSGILSKIVWFFEDQTDLETEYRSNANVDDAYSRVFGI
What is the function of this protein?
Component of the spindle pole body (SPB) required for insertion of the nascent SPB into the nuclear envelope and for the proper execution of spindle pole body (SPB) duplication.
What are the official names of this protein?
Monopolar spindle protein 2.
What is the protein family that this protein belongs to?
Belongs to the MPS2 family.
What are the subcellular locations of this protein?
Nucleus membrane; Single-pass membrane protein. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body.
Protein: Y1519_MYCTO
Sequence: MRCGCLACDGVLCANGPGRPRRPALTCTAVATRTLHSLATNAELVESADLTVTEDICSRIVSLPVHDHMAIADVARVVAPFGEGLARGG
What are the official names of this protein?
Uncharacterized protein MT1569.
What is the protein family that this protein belongs to?
To M.tuberculosis Rv3402c.
Protein: RPO11_THEAC
Sequence: MQRERTAESSLRVISKEKNSITVEMINYDNTLLRTLVEEILKDDQVDEARYYIKHPVIDNPQIYVRVKSGKPQSAIKRAVRKLSKLYEDLGTQFQKEFQRYESDHMIKAVE
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo11, DNA-directed RNA polymerase subunit L.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: R3HC1_MOUSE
Sequence: MALLCLDGVFLSSAENDFVHRVQEELDRFLLQKQLSKVLLFPPVSSRLRYLIHRTAENFDLLSSFSVGEGWKRRTVICHLDIRVPSSDGPSGPCRPPASHPSKYRGPRYTSHQGAAAGPRGAPAGRWHRGRKPDQPLYVPRVLRRQGGPVAASIPGIKGEDPAGAVSEEEPREAGAGDAEADQGIAMLVTQELLKSPDPGHANEPQMGLGDTEPSENPEKEQGAETAVQQGSGAQLAMEEENRSHGMRSLVDQEEEEIEGEEEEKVDEKEEDTGKQKERVDEEEEKTDAQEGKVDSEGERMDEGEDKVDAEEEDEDEADADHGDFSELLQEITANLTEKEIKIEKIHLDTSAFTEELPGERDLTHLVEIYDFKPTLKTEDLLATFSEFQEKGFRIQWVDDTHAIGIFPCPASALEALAKDFSVLKIRPLTQGTKQSKLKALQRPKFLRLSKERPQTDSAVARRLVARALGLQHNRKKELPTPPSVLPS
What are the official names of this protein?
R3H and coiled-coil domain-containing protein 1.
Protein: MUTS_ECOBW
Sequence: MSAIENFDAHTPMMQQYLRLKAQHPEILLFYRMGDFYELFYDDAKRASQLLDISLTKRGASAGEPIPMAGIPYHAVENYLAKLVNQGESVAICEQIGDPATSKGPVERKVVRIVTPGTISDEALLQERQDNLLAAIWQDSKGFGYATLDISSGRFRLSEPADRETMAAELQRTNPAELLYAEDFAEMSLIEGRRGLRRRPLWEFEIDTARQQLNLQFGTRDLVGFGVENAPRGLCAAGCLLQYAKDTQRTTLPHIRSITMEREQDSIIMDAATRRNLEITQNLAGGAENTLASVLDCTVTPMGSRMLKRWLHMPVRDTRVLLERQQTIGALQDFTAGLQPVLRQVGDLERILARLALRTARPRDLARMRHAFQQLPELRAQLETVDSAPVQALREKMGEFAELRDLLERAIIDTPPVLVRDGGVIASGYNEELDEWRALADGATDYLERLEVRERERTGLDTLKVGFNAVHGYYIQISRGQSHLAPINYMRRQTLKNAERYIIPELKEYEDKVLTSKGKALALEKQLYEELFDLLLPHLEALQQSASALAELDVLVNLAERAYTLNYTCPTFIDKPGIRITEGRHPVVEQVLNEPFIANPLNLSPQRRMLIITGPNMGGKSTYMRQTALIALMAYIGSYVPAQKVEIGPIDRIFTRVGAADDLASGRSTFMVEMTETANILHNATEYSLVLMDEIGRGTSTYDGLSLAWACAENLANKIKALTLFATHYFELTQLPEKMEGVANVHLDALEHGDTIAFMHSVQDGAASKSYGLAVAALAGVPKEVIKRARQKLRELESISPNAAATQVDGTQMSLLSVPEETSPAVEALENLDPDSLTPRQALEWIYRLKSLV
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: KCY_CAUVC
Sequence: MGFVIAVDGPAASGKGTVAGRLAALYGYPLLDTGLLYRAVGVAILDGAGDLDDPIAAEAVARALDLSALDRAEVRTRAAGEAASRCAVHPGVRAALLDLQQTFAAREPGSVIDGRDIGTVIAPHAPAKLYVTARPEVRAERRWKQLVGQGEDVAFEDILADIHKRDARDGGRKDAPMTQAPDAVLLDTSEMTIEQAFDAARRIVEDARARHRL
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP_SOLTU
Sequence: MPIGVPKVLFRNPGDPISSWVDVYNRLYRERLLFLGQGISTDLSNQLIGLMMYLSMEDENKELYLFVNSPGGWVIPGIAIYDTMQFVRPDIHTICIGLAASMGSFILAGGQLTKRIAFPHARVMIHEPYSAFYMAQVGEFVMEAVELMKLRETLTRVYAERTGKPFWVVHEDMERDIFMSATEAQAYGIVDFVAVQGK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: TRMD_RHOBA
Sequence: MRFDVVTLFPAIFDGYLTQSLLDKAIVRGLVEIQRHNLRDWAEDTPHRKVDDRPFGGGPGMLLQVEPTVTCVRDVDAMADVPARKILLTPQGRRLDQRLAEDLATSDRIMLMCGRYEGFDQRVLDILQPEEISIGDFVLNGGEVAAMTIIDAVVRLLPGVLGDEQSSLDDSFSRGNRMLEFPQYTRPREFEGHTVPDVLLSGDHAAIAAWRAEQSRARTIDRRRDLLPEHSKNNPEQTNKLS
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_CAMJE
Sequence: MTEITAAMVKELRESTGAGMMDCKNALSETNGDFDKAVQLLREKGLGKAAKKADRLAAEGLVSVKVSDDFTSATVSEINSETDFVAKNDQFIALTKDTTAHIQSNSLQSVEELHSSTINGVKFEEYLKSQIATIGENLVVRRFATLKAGANGVVNGYIHTNGRVGVVIAAACDSAEVASKSRDLLRQICMHIAAMRPSYLSYEDLDMTFVENEYKALVAELEKENEERRRLKDPNKPEHKIPQFASRKQLSDAILKEAEEKIKEELKAQGKPEKIWDNIIPGKMNSFIADNSQLDSKLTLMGQFYVMDDKKTVEQVIAEKEKEFGGKIKIVEFICFEVGEGLEKKTEDFAAEVAAQL
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_CAUVC
Sequence: MARKSFGQHFLLDLNVTRKIARLAQVGEGDTVVEVGPGPGGLTRALLETGARVVAIEKDSRFLPLLAEVAEVAEGRLELVEGDALKVDAAQAAGGPAHVVSNLPYNVGTQLLINWLTGPFRPLSMTLMFQKEVADRIVAQPGDDAYGRLAVIAQTLCEARTVMDLPAKAFTPPPKVASAVVRLVPKAEPPPAEVVAALERVTAAAFGQRRKMLRSSLKALGGADLCERAGVSPDARAEVIDLAGFLDLARATLGGADQ
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRI72_XENTR
Sequence: MSTPQLMQGMQKDLTCPLCLELFRAPVTPECGHTFCQGCLTGAPKNQDQNGSTPCPTCQTPSRPETLQINRQLEHLVQSFKQVPKGHCLEHLDPLSVYCEQDKELICGVCASLGKHKGHNIITAAEAYAKLKRQLPQQQVILQEARLKKEKTVAVLDRQVAEVQDTVSRFKGNVKHQLNAMRSYLSIMEASLSKEADNAEHTATEALLVERKTMGHYLDQLRQMDGVLKDVESQEQTEFLRKYCVVAARLNKILAESPPPGRLDIQLPIISDEFKFQVWRKMFRALMPALENLTFDPDTAQQNLVVFSDGKSVECSEQKQSVSDEPNRFDKSNCLVSKESFTEGEHYWEVLVEDKPRWALGVISETANRKGKLHASPSNGFWLIGCKEGKVYEAHTEQKEPRVLRVEGRPEKIGIYLSFSDGVVSFFDSSDEDNIKLLYTFNERFSGRLHPFFDVCWHDKGKNAQPLKIFYPPAEQL
What is the function of this protein?
Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites.  Specifically binds phosphatidylserine.  Acts as a sensor of oxidation: upon membrane damage, entry of extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site.  This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation.  Probably acts upstream of the Ca(2+)-dependent membrane resealing process (By similarity).
What are the official names of this protein?
Tripartite motif-containing protein 72, Mitsugumin-53, Mg53.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cell membrane, sarcolemma. Cytoplasmic vesicle membrane. Note=Tethered to plasma membrane and cytoplasmic vesicles via its interaction with phosphatidylserine.
Protein: ALR_STRZJ
Sequence: MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAYGHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFTLTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVCVEGIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVRMGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIATVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNGDKEITATQVATYRVTINYEVVCLLSDRIPREYY
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: YBEY_METCA
Sequence: MIDLTLQRASTSAVPDSAAFRLWAEAALEKPHAEVVIRIVDREESAALNSTYRGKTGPTNVLSFPFVVPEGVPNDLLGDLVICAPVVEREAAEQGKPVEAHWAHMVVHGMLHLQGYDHIEEAEAEIMENREIAILRGLGMENPYREIRPE
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_VIBA3
Sequence: MIGRLRGTLIEKQPPELLIEVSGVGYEVQMPMSCFYELPNVGEEAIIYTHFVVREDAQLLYGFNTVKERALFREVIKANGVGPKLGLGILSGMTASQFVQSVEREDISTLVKLPGVGKKTAERLVVEMKDRLKGWGAGDLFTPATDAAPMDSMPTVHDAEEEAVSALLALGYKPTQASKVVSQVAKDGMTSEQLIREALKSMV
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: BRD3_MOUSE
Sequence: MSTTAAAPTGIPAVPGPVNPPPPEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMPQEEVELLPPAPKGKGRKPAAGAQNAGSQQVAAVSSVSPATPFQNIPPTVSQTPVIAATPVPTITANVTSVPVPPPAAPPPPATPIVPVVPPTPPVVKKKGVKRKADTTTPTTSAITASRSESPPPLSEPKQAKVVARRESGGRPIKPPKKDLEDGEVPQHAGKKGKLSEHLRHCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDSREYPDAQGFAADIRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPMEAPALPAPTAPIVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKDKDKEKEKHKAKSEEEKKAKAAPAAKQAQQKKAPTKKANSTTTASRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKKQRKPLSTSGKKQAAKSKEELAQEKKKELEKRLQDVSGQLNSKKPTKKEKSGSAPSGGPSRLSSSSSSESASSSSSGSSSDSSDSE
What is the function of this protein?
Chromatin reader that recognizes and binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling and interaction with transcription factors (PubMed:21536911).  Regulates transcription by promoting the binding of the transcription factor GATA1 to its targets (PubMed:21536911).
What are the official names of this protein?
Bromodomain-containing protein 3, Bromodomain-containing FSH-like protein FSRG2.
What are the subcellular locations of this protein?
Nucleus. Note=Detected on chromatin.
Protein: VM2TO_ERIMA
Sequence: QEEPCATGPCCRRCKFKRAGKVCRVARGDWNDDYCTGKSCDCPKNPWNG
What is the function of this protein?
Is a potent inhibitor of ADP-induced platelet aggregation.  Acts by binding to alpha-IIb/beta-3 (ITGA2B/ITGB3) receptor on the platelet surface.  Binds with the same high affinity to resting and activated platelets.  Also binds the alpha-4/beta-1 (ITGA4/ITGB1) integrin.  Is a potent inhibitor of human and murine melanoma metastases in mouse model systems, also due to the inhibition of binding between the alpha-4/beta-1 integrin and the vascular cell adhesion protein VCAM1.  Reacts neither with the integrin alpha-V/beta-3 (ITGAV/ITGB3) vitronectin receptor nor with the integrin alpha-5/beta-1 (ITGA5/ITGB1) fibronectin receptor.  Has no effect on cell proliferation or angiogenesis.  Specifically inhibits cell migration on fibronectin, but not that on collagen IV or laminin.  May involve fibronectin-binding integrins that mediate cell migration.
What are the official names of this protein?
Disintegrin eristostatin.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-II subfamily. P-IIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PAT_ECO7I
Sequence: MNRLPSSASALACSAHALNLIEKRTLDHEEMKALNREVIEYFKEHVNPGFLEYRKSVTAGGDYGAVEWQAGSLNTLVDTQGQEFIDCLGGFGIFNVGHRNPVVVSAVQNQLAKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGTESVEAALKLAKAYQSPRGKFTFIATSGAFHGKSLGALSATAKSTFRKPFMPLLPGFRHVPFGNIEAMRTALNECKKTGDDVAAVILEPIQGEGGVILPPPGYLTAVRKLCDEFGALMILDEVQTGMGRTGKMFACEHENVQPDILCLAKALGGGVMPIGATIATEEVFSVLFDNPFLHTTTFGGNPLTCAAALATINVLLEQNLPAQAEQKGDMLLDGFRQLAREYPDLVQEARGKGMLMAIEFVDNEIGYNFASEMFRQRVLVAGTLNNAKTIRIEPPLTLTIEQCELVIKAARKALAAMRVSVEEA
What is the function of this protein?
Catalyzes the aminotransferase reaction from putrescine to 2-oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline.  This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate (gamma-aminobutyrate or GABA) via 4-aminobutanal.  Also functions as a cadaverine transaminase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
What are the official names of this protein?
Putrescine aminotransferase, PAT, PATase, Cadaverine transaminase, Diamine transaminase, Putrescine transaminase, Putrescine--2-oxoglutaric acid transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. Putrescine aminotransferase subfamily.
Protein: CH60_HAES1
Sequence: MTAKDVKFGNDARVKMLAGVNVLADAVKVTLGPKGRNVILDKAFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIVSEGLKAVAAGMNPMDLKRGIDKAVNAVVEELKILSKPCETSKEIEQVGTISANADETVGKLIAQAMEKVGKEGVITVEDGSGLSDELDVVEGMQFDRGYLSPYFINKPEAATVELDNPFILLVDKKISNIRELLPVLEGVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIAILTAGTVISEEIGMELEKATLEDLGQAKRVVINKDNTTIIDGIGDEAQIKGRVAQIRQQIEEATSDYDKEKLQERVAKLAGGVAVIKVGAATEVEMKEKKDRVDDALHATRAAVEEGIVAGGGVALIRAATKVATTLKGDNEDQDVGIKLALRAMEAPLRQIVTNAGEEASVVASAVKNGEGNFGYNAGTEQYGDMIAMGILDPTKVTRSALQFAASIAGLMVTTECMVADLPKEEKADLTGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZAPA_HAEI8
Sequence: MSLKLVEILVLGQVLRLNVPIEQEELLRQAARNLDILVSEMKEKTGLIQLDRVLSIVALNLSFELSQEKNKTAKIEEVLRTGIQQLDHSLENIRVTKEPH
What is the function of this protein?
Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring.  It is recruited early at mid-cell but it is not essential for cell division (By similarity).
What are the official names of this protein?
Cell division protein ZapA, Z ring-associated protein ZapA.
What is the protein family that this protein belongs to?
Belongs to the ZapA family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes at mid- cell.
Protein: RL29_METFK
Sequence: MKASELRNKTVEELNNELIELRRAQFSLRMQLATQQLNKVDQVGKVRRDIARVRSVLAEKAKAANASQA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: Y577_BURP6
Sequence: MRIVLITGISGSGKSVALNALEDAGYYCVDNLPPHVLPELARYLAHEGQNRLAVAIDARSSASLDEMPGLIRALSREHDVRVLFLNASTQALIQRFSETRRRHPLSGSPSHDADVGLLVSLEEAIERERELVAPLAEFGHQIDTSNLRANVLRTWVKRFIEQKNDDLVLMFESFGFKRGVPLDADFMFDVRALPNPYYDHELRPLTGLDQPVVAFLDALPVVHQMLDDIETFLVKWLPHFREDNRSYLTVAIGCTGGQHRSVFLAETLAARLSRQASVIVRHRDAPVAVDASSRLVT
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein BURPS668_0577.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: SYS1_YEAST
Sequence: MVSIRRYLRVPNELKPSQIFKQDSLSPSKIGLQIVLLQIFYYTTAIVLFYCWAKLAGYDLNIKEWLFSWENIDFTNAYGLSISLLWLLDSLICVFFLTVIVGRSKLAWDFAITIHAINFIVVFLYTRKFPSFSWFFLQILSSLILIFLGTWTTRWRELRDTFFEGLVDPNEGEVGLVTPSQQHSNHSELEQSPIQLKDLESQI
What is the function of this protein?
Necessary for the targeting of ARL3 to the Golgi.  Involved in protein trafficking.  May serve as a receptor for acetylated ARL3.
What are the official names of this protein?
Protein SYS1.
What is the protein family that this protein belongs to?
Belongs to the SYS1 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: CPSM_MOUSE
Sequence: MTRILTACKVVKTLKSGFGFANVTTKRQWDFSRPGIRLLSVKAKTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEALTDPAYKGQILTMANPIIGNGGAPDTTARDELGLNKYMESDGIKVAGLLVLNYSNDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTMLGKIEFEGQSVDFVDPNKQNLIAEVSTKDVKVFGKGNPTKVVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFTQMEYDGLLIAGGPGNPALAQPLIQNVKKILESDRKEPLFGISTGNIITGLAAGAKSYKMSMANRGQNQPVLNITNRQAFITAQNHGYALDNTLPAGWKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVSPGPTDTEYLFDSFFSLIKKGKGTTITSVLPKPALVASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADAVYFLPITPQFVTEVIKAERPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESMEDALKAADTIGYPVMIRSAYALGGLGSGICPNKETLIDLGTKAFAMTNQILVERSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSVNVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSVDGFTPRLPMNKEWPANLDLKKELSEPSSTRIYAIAKALENNMSLDEIVRLTSIDKWFLYKMRDILNMDKTLKGLNSDSVTEETLRKAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDIKFDEHGIMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEACNGCIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFANSVGYPCLLRPSYVLSGSAMNVVFSEDEMKRFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKEGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGESIDEKRLPTLEQPIIPSDYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPNNNTKFVHDNYVIRRTAVDSGIALLTNFQVTKLFAEAVQKSRTVDSKSLFHYRQYSAGKAA
What is the function of this protein?
Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell.
What are the official names of this protein?
Carbamoyl-phosphate synthase [ammonia], mitochondrial, Carbamoyl-phosphate synthetase I, CPSase I.
What are the subcellular locations of this protein?
Mitochondrion. Nucleus, nucleolus.