PharMolix/UniProtQA huggingface dataset:
Protein: ENO_MYCUA
Sequence: MPIIEQVGAREILDSRGNPTVEVEVALIDGTFARAAVPSGASTGEHEAVELRDGGDRYGGKGVKKAVEAVLDEIGPAVIGLNADDQRLVDQALVDLDGTPDKSRLGGNSILGVSLAVAKAASESAELPLFRYIGGPNAHILPVPMMNILNGGAHADTGVDIQEFMVAPIGAPSFSEALRWGAEVYHALKAVLKKAGLSTGLGDEGGFAPDVASTTAALDLISQAIEAAGFKPGVDVALALDAAANEFHADGSYTFEGTPRTAAQMTEFYAGLLGSYPVVSIEDPLYENDWDGWAALTAEIGDRVQIVGDDVFVTNPERLEEGIDRGVANALLVKVNQIGTLTETLDAVALAHHSGYRTMISHRSGETEDTIIADLAVAVGSGQIKTGAPARSERVAKYNQLLRIEEALGDAARYAGDLAFPRFVADPK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: Y094_STAA8
Sequence: MKKLATVGSLIVTSTLVFSSMPFQNAHADTTSMNVSNKQSQNVQNHRPYGGVVPQGMTQAQYTELEKALPQLSAGSNMQDYNMKLYDATQNIADKYNVIITTNVGVFKPHAVRDMNGHALPLTKDGNFYQTNVDANGVNHGGSEMVQNKTGHMSQQGHMNQNTHEPTATHATRSYAIIKPSNDESKSKYAFIKSSNEPK
What are the official names of this protein?
Uncharacterized protein SAOUHSC_00094.
What are the subcellular locations of this protein?
Secreted. Note=Suggested to be cell wall associated in the paper, however the bioinformatics evidence however is poor for cell wall localization.
Protein: NODG_AZOBR
Sequence: MSQKIALVTGAMGGLGTAICQALAKDGCIVAANCLPNFEPAAAWLGQQEALGFKFYVAEGDVSDFESCKAMVAKIEADLGPVDILVNNAGITRDKFFAKMDKAQWDAVIATNLSSLFNVTQQVSPKMAERGWGRIINISSVNGVKGQAGQTNYSAAKAGVIGFTKALAAELATKGVTVNAIAPGYIGTDMVMAIREDIRQAITDSVPMKRLGRPDEIGGAVSYLASEIAGYVTGSTLNINGGLNYQ
What is the function of this protein?
Proposed to modify Nod factor fatty acyl chain.
What are the official names of this protein?
Nodulation protein G.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: XPOT_ASPFC
Sequence: MEEQVANAIEIASNPSADPALKTQAFDFVNQLRSDPSGWQVCLSLFTQTPQRSGIVRHVALEVVNSAAQGGLIDLQALAYVKDGLLAYLRQVYGQDAGASDPPNIQNKIAQTITFLFSALYASGWESFFDDLLGLTQKSPSSTTRDNASGIIFYLRVINSIHDEIGDVLVSRSRNEQDKANALKDLIRQRDMQKITSSWQQILSEWRDGNDVIVEMCLKAVGSWVSWIDIGLVVNQTMLDLLFRQLGRAQKEDLRQGEEKVRDAAVDVFTEIIGKKMKPEDKIDMIIFLNLDTIVSQLSNSPPLHGNRFTFKYDTDLAETVAKLVNITVIDIVRALEQEGVSTECKEKANGLLQAFLPHILRYFSDEYDEVCSTVIPCVSDLLTYLRRIAKVNPALASQHSSILLPILKAIIAKMRYDETSSWGEEDEQTDEAEFQELRKRLGILQQMIASINEQLYMEVVSEMVATTFENLRQSGSQMDWRDLDLALHEMFLFGDLAVKAGSLYTKGNPNNQAAERLIEMMLRMVESDIRSFTHPATQLQYTEICVRYSSFFHHHTHLIPGVLENFLQLVHHPIKKVKTRSWYLFQRLVKQLRQYVGNVAQTVVEALGDLLVIRAELPSEVSEGDEMSSEDHELADAIFNSQLYLFEAVGIICSTPTISPDKQVLYLQAVLNPIFLDMEKNLEAAKSQDERAILQIHHDIMALGTLARGFSDWMPGTNTPATLPAPEVSAAFNQVAEATLVALESLKSSFNVRTAARFAFSRLIGVLGSRILPQLPRWIDGLLTQTSSRDEMALFLRLLDQVIFGFKGEIFSILDTLLTPFLQRVFSGIADPTTGTDDEIQLAELKREYLNFLLAVLNNDLGAVIISERNQPIFETVISTIEHFSKDIDDFTTAKMAFSVLSKMSSSWGGPDVIAEASNGTPPSQAPLPGFGQFMITRFSPLCWALPSTPSFNSKDAQAKQVLAEAGGLQRTIYAKTGMEYLTYLRDRELPGMGMGGELIEEFVGALSRLDLKGFRQFFPVCLSNFHILSI
What is the function of this protein?
tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.  Involved in pre-tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease (By similarity).
What are the official names of this protein?
Exportin-T, Exportin(tRNA), Karyopherin-beta, tRNA exportin.
What is the protein family that this protein belongs to?
Belongs to the exportin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm.
Protein: Y1554_LISMF
Sequence: MSGHSKWNNIQGRKNAQDSKRSKVFQKLAREIFVAAKKGPDPNLNPSLRLVMDKAKAVNMPNDNIKRAIDKAAGNTSGENYDEVTYEGYAPGGIAVLVHALTDNKNRTSTNVRVAFNKNGGSLGETGSVSYMFDRKGYLVILREGLDVDEEEFMLEAIEAGADDVEVSEDVFEIFTDPATFPEVKEALQEAGYTFATAELSMFPTVYNEVAENNQTQFDKMLEALEDDDDVQEVYTNAEIN
What are the official names of this protein?
Probable transcriptional regulatory protein LMOf2365_1554.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSTT7_ANOGA
Sequence: MTPVLYYLPPSPPCRSVLLLAKMIGVELELKALNVMEGEQLKPDFVELNPQHCIPTLDDHGLVLWESRVILAYLVSAYGKDENLYPKDFRSRAIVDQRLHFDLGTLYQRVVDYYFPTIQLGAHLDQTKKAKLAEALGWFEAMLKQYQWSAANHFTIADIALCVTVSQIEAFQFDLHPYPRVRAWLQKCKDELQGHGYKEINETGAETLAGLFRSKLKQ
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
What are the official names of this protein?
Glutathione S-transferase D7, Aggst1-7, GST class-theta, Gst1-beta.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Theta family.
Protein: GCST_SYNR3
Sequence: MLHTPLFELCREAGGRMVPFAGWEMAVQFEGLMAEHRAVRQRCGVFDISHMGVLTLTGSGVKDKLQGLVPSDLQRIGPGEAQYTVLLNEAGGIRDDLIVYDRSDTEVVVVINAACADSDTAWIKQQLEPQGVSVSDRKAGGVLLALQGPEAVGRLERLCGESLAGVPRFGHRDLTIKGEPVFAARTGYTGEDGFELLLTASAGQSLWRQLLEDGVAPCGLGARDSLRLEAAMHLYGNDMDANTSPLECGLGWLVHLEMPIEFVGREALERQTAEGVSRKLVGLQLQGRAIARHDYPVLHNGEPVGVVTSGTFSPTLEHPVALASVRADLAKLGNELMVEIRGRQEPAVVVKRPFYRRQG
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: Y6541_BACAN
Sequence: MSNEQGKGMGFFGNKGKPASEKKDEKKTKLDLDYKPDLNPSTPYDPTLPVKATLVNGDKRGTLRIPLETKHEFDALLEISEYQYTYELLGEMLDTWMKKLTPEQLRLFHASLENIKRKAAIKEAKKKK
What are the official names of this protein?
Uncharacterized protein pXO2-40/BXB0041/GBAA_pXO2_0041.
Protein: RPPH_KLEP7
Sequence: MIDDDGYRPNVGIVICNRQGQVMWARRYGQHSWQFPQGGINPGESAEQAMYRELFEEVGLSRKDVRILASTRNWLRYKLPKRLVRWDTKPVCIGQKQKWFLLQLIGNDADINMQTSSTPEFDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFASVTMSLAESAPKPQNAPAYRRKRG
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: CH076_MOUSE
Sequence: METGCWVLGGEFEDSVFEQRPERRPEPPSPYRAKLCEPQWFYEETECSDDIEVLTLKKFRGDLAYRRQEYEKALQEYSSISEQLPSTNFAMKRDVQEGQARCLAHLGRHEEALEMAADLESKATNTDHLTVVLHLHLAVFSSLQSREHTILCLHKLIALHPLNPWSWCKLAEAYLSPGPGLPAGVSPQGQKSSASSDKAVGPSSVHSGTGSLLSLPTTLPENALLSVEASGSAQENMPSLARRREEAQMEARRKACASLLRARLLLQLAQSQQTSFALEKNLRTQQEIAGKVKDFNFREDTLLLMEEAMGEDIVPEKIKEELHSEVKCVGPGALTAMVVASSKEFEDKWFRKIKDHFCPLGNQFHVEVEIIA
What are the official names of this protein?
Uncharacterized protein C8orf76 homolog.
Protein: RECF_STRP6
Sequence: MWIKELELKHYRNYDHLLASFSSGLNVFIGNNAQGKTNFLEAIYFLSLTRSHRTRADKELIHFDHSTVSLTGKIQRISGTVDLEINLSDKGRVTKINALKQAKLSDYIGTMMVVLFAPEDLQLVKGAPSLRRKFIDIDLGQIKPVYLSELSHYNHVLKQRNSYLKSAQQIDAAFLAVLDEQLAGYGARVMEHRIDFINALEKEANTHHQAISNGLESLSLSYQSSVVFDKKTNIYQQFLHQLEKNHQKDFFRKNTSVGPHRDDLAFYINGMNANFASQGQHRSLILSLKMAEVSLMKALTGDNPILLLDDVMSELDNTRQTKLLETVIKENVQTFITTTSLDHLSQLPEGIRIFHVTKGTVQIDSDIH
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVC_BLOFL
Sequence: MNNYFNKLTFIQKIKHLGQCRLMKKNEFSDGVRALLSKKIVIIGCGSQGLNQGLNMRDSGLNITYALRRDSIINQSQSYIRAMKYGFSVGTYDELIPEADFVINLIPDKYHESLIQKIEPLMKYKAVLGYSHGFHIVEIGVKIRQDITVIMVAPKCPGTEVRQEYQRGFGVPALIAVHEENNAYGTGMELAKSWACSIGSNKAGVLESSFVAEVKSDLMGEQTVLCGMLQVGSIFCFDKMVEDGLDSGYAGKLVQNGWEVITEALKQGGITLMMDRLSNVSKLRAFELSDQLKNILTPVFEKHMEDILDGSFSKNMMLDWINKDCKLLSYRQNNSQLLFEKAPVYCETILEQTYFDHGVLMVAIIKASVELAFDIMVKSGIKPESAYYESLHELPLIANTIARKRLYEMNMVISDTAEYGNYLFSDFVLPLLKKEFVPYLKRGDLDLSHVNNIVHIDNILLRDINEMIRTHPIEKVGVQLRSYMKDMVSLSF
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: VATA_CHLT2
Sequence: MVATSKQTTQGYVVEAYGNLLRVHVDGHVRQGEVAYVSVDNTWLKAEIIEVVGDEVKIQVFEETQGISRGALVTFSGHLLEAELGPGLLQGIFDGLQNRLEILADTSLFLRRGEYVNAICRETVWAYTQKASVGSVLSRGDVLGTVKEGRFDHKIMVPFSCFEEVTITWVISSGNYTVDTVVAKGRTSTGEELEFTMVQKWPIKQAFLEGEKVPSHEIMDVGLRVLDTQIPVLKGGTFCTPGPFGAGKTVLQHHLSKYAAVDIVVLCACGERAGEVVEILQEFPHLKDPHTGQSLMHRTCIICNTSSMPVAARESSIYLGITIAEYYRQMGLHILLLADSTSRWAQALREISGRLEEIPGEEAFPAYLASRIAAFYERGGAVKMKDGSEGSLTICGAVSPAGGNFEEPVTQATLSVVGAFCGLSKARADARRYPSIDPMISWSKYLDSVAEILEKKVPGWGESVKQASRFLEEGAEIGKRIEVVGEEGISMEDMEIFLKSELYDFCYLQQNAFDAEDCYCPFDRQIELFSLMNHIFNSRFCFDCPDNARSFFLELQSKIKTLNGQKFLSEEYQKGLEVIYKLLESKMVQTA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type alpha chain is a catalytic subunit.
What are the official names of this protein?
V-type ATP synthase alpha chain, V-ATPase subunit A.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: GO_HHV6Z
Sequence: MLHISRLGLFLALFAIVMHSVNLIKYTSDPLEAFKTVNRHNWSDEQREHFYDLRNLYTTFCQRNLSLDCFTQILTNVFSWNIRDLQCKSAVNLSPLQNLPRAETKIVLSSTAANKSIVASSFSLFYLLFATLSTYTADPPCVELLPFKILGTQLFDIKLTDESLQMAISKFSNSNLTRSLTPFTPEIFFNYTSFVYFLLYNTTSCIRSNDQYFEHSPKPINVTTSFGRAIVNFHSILTTTPSSTPSSTSASITSPHIPSTNTPTPEPSPVTKNFTELQTDTIKVTPNTPTITAQTTESIKKVVKRSDFPRPMYTPTDIPTLTIRRNATIKTEQNTENPTENPKSPPKPTNFENTTIRIPETFESTTVATNTTQKLESTTFATTIGIEEISDNIYSSPKNSIYLKSKSQQSTTKFTDTEHTTPILKFTTWQDAARTYMSHNTEVQNMTENFIKISLGETMGITPKEPTNPTQLLNVKNQTEYANETHSTEVQTVKTFKEDRFQRTTLKSSSEPPTVQTLSVTPKKKLPSNVTAKTEVQVTNNALPSSNSSHSITKVTEEPKQNRMSASTHGEINHTEIPRMTPILNAHTWEKSTTPQWPFTAETSLTTSSKSAILTWSNLLTTPKEPLTNTSLRSTNHITTQLTTSNRTQSAKLTKAHVSSQTTNIYPQTITERSTDVKKKSSTESREANKTLPGNDYRVTDKNSHNHPDNLTTKAYSTQNATHYTYNERHDLNNTDST
What are the official names of this protein?
130 kDa Glycoprotein O, gO-130K, Glycoprotein U47.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae U47 family.
What are the subcellular locations of this protein?
[80 kDa Glycoprotein O]: Virion. Host cell membrane.
Protein: DUT_ACIBS
Sequence: MKVQVKLLDPRLGKEWPLPSYATAGSAGLDLRACLDEAIEIEPGQTVLVKTGMAIYIHDVNFAGLILPRSGLGHKHGIVLGNLVGLIDSDYQGELMVSVWNRGQTTFRLEPGERLAQYVLVPVVQAEFEQVEEFEETLRGAGGFGHTGKQ
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: GPR_BACP2
Sequence: MEKQKLDLSAYQIRTDLAVETKEILEQENDPNVITKDGIQGIVEKEKEEHGIRIRTVEITKEGEALTSKKAGTYLTLEAQGIREKDSEMQEKVVEVFAHHFAQFLKDRGIQTDASCLVVGLGNWNVTPDALGPLTVESLLVTRHLFELQPENVQEGYRPVSSLSPGVMGLTGIETSDIIQGVIERSKPDFVIAIDALAARAVERVNTTIQISDTGIHPGSGVGNKRKELSKETLGIPVIAIGVPTVVDAVTIASDTIDYVLKHFGRELKDDRPSRSLVPAGLTFGKKKVLNEEDLPDEETRQSFLGIVGTLPEEEKRQLIHEVLAPLGQNLMVTPKEVDTFIDDMANVLANGLNTALHQKISQDNMGSYNH
What is the function of this protein?
Initiates the rapid degradation of small, acid-soluble proteins during spore germination.
What are the official names of this protein?
Germination protease, GPR endopeptidase, Germination proteinase, Spore protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase A25 family.
Protein: PANC_XANAC
Sequence: MIQTLTDLSALRALVNGWKREGLRVALVPTMGNLHAGHYSLVMLARQYADRVVSSVFVNPTQFGPNEDFARYPRTPEADLRGLEDAGCDALWLPDVDTMYPLGTALATPIHAPGVSDVLEGECRPGHFDGVCTVVARLFNQVQPDVAAFGKKDYQQLAVIRQMVADLAFPIEILGGSIVREADGLAMSSRNQYLSAEDRPISSTIRKVLLQMRDSYAAGTPRAQVEDAASHTLEQAGFRVDYAVVRLPDLSEPGDSHAGARVALIAARLGNTRLIDNLEF
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUB12_ORYSJ
Sequence: MPKRVADEIAALPEPRGPLRRPCADLSRRVRLLAPLLDHLPASSSSSSSTPLADALGAARDLLRKTRDGSKIDQAMRGDAFLDEFAGVNRQIHLALDALPYNTFHMPQEVQEQVALVHSQFQRASTRTDPPDTQLSMDLAWALTDNPSDPALLTRISHKLQLHTMADMKNESIALHNMVISTAGEPDGCVDQMSSLLKKLKDCVVTEDHANDALTTRSASIKHRSPIIPDEFRCPISLELMQDPVIVSSGQTYERSCIQKWLDSGHKTCPKTQQPLSHTSLTPNFVLKSLISQWCEANGIELPKNKQNSRDKKAAKSSDYDHAGLVSLMNRLRSGNQDEQRAAAGEIRLLAKRNVNNRICIAEAGAIPLLVNLLSSSDPRTQEHAVTALLNLSIHENNKASIVDSHAIPKIVEVLKTGSMETRENAAATLFSLSVVDENKVTIGAAGAIPPLINLLCDGSPRGKKDAATAIFNLCIYQGNKVRAVKAGIVIHLMNFLVDPTGGMIDEALSLLSILAGNPEGKIVIARSEPIPPLVEVIKTGSPRNRENAAAILWLLCSADTEQTLAAKAAGVEDALKELSETGTDRAKRKASSILELMHQANEDSLKGNGH
What is the function of this protein?
Possesses E3 ubiquitin-protein ligase in vitro.
What are the official names of this protein?
U-box domain-containing protein 12, Plant U-box protein 12, OsPUB12, RING-type E3 ubiquitin transferase PUB12.
Protein: MNMA_METNO
Sequence: MNSLDLPKAPQDTRVVVAMSGGVDSSVVAGLLKRQGYDVVGITLQLYDHGAATHRRGACCAGQDIHDARRAAETLGIPHYVLDYEDRFREAVIDRFADSYIHGETPIPCVECNRSIKFRDLLATALDLGADALATGHYVASRPRPGGSRALYRALDPARDQSYFLYATTAEQLDVLRFPLGELPKDETRRLAREFGLSVADKPDSQDICFVPQGRYQDVIARLRPDSVRPGEIVHLDGRTLGRHDGIIGFTVGQRRGLKLATGEPLYVVRLDPETARVVVGPREALATSVIRLAETNWLGDEPLTELDGMPVAVRVRSTREPRPATLRWNRAASCAEVMLATPEDGVSPGQACAIYADEGPRARVLGGGTILRVEASRREAA
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRCA_EXIS2
Sequence: MLTDRQLLILRAIVDDYIKTAQPVGSRTLSKRSDVTFSSATIRNEMADLEEMGLIEKPHTSAGRIPSELGYRFYVDHLIRPESISPQEAKALKSLFAHSVNENDRLIRHTADLLSELTHYTTLVLGPKEEGQRLHHLELIPLAEGRVVIVLVTETGHVEHKTLQLAEALSREAASRLMERLNQTLRGTPLRQLRLRLLEEIRRFRSEHSEQTTLLSKALDIVLTDQHEERPLIYLGGKANMFDQPEFQDVAKLRPVLELIEQQEALFDFLSPSLDNQILITIGSENNVDALKDCSVIRAHYSVDGVSLGTLALIGPKRMDYNRGINSIIHLLQAFQTELRKNSLD
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: Y058_HVAVE
Sequence: MSLTERIGQTPKAYELANERGPFSVEVYLNPGTSNTYQYVATTRNKFNNTDYDDLPWNYTSGKKVVTATGVVSGGERYVFLLRSEIAQDIQVTMYNTNGGSNPLNNSNVTRSNVDSSSYYQQPPQVVYNNGDLYGSRTGYSGAELGASIDKGIASLWGYLKQPLVMVGIAAVVGYLIYRYYYMSRPIGFGSSGAYDVPLLDTPLLRDSYRLPQSFTRDPLFRNSV
What are the official names of this protein?
Uncharacterized protein ORF58.
What is the protein family that this protein belongs to?
Belongs to the ascovirus HvAv ORF58 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: YMDA_SALTY
Sequence: MSVIKKNIPAIGLCICAFFIHSAVGQQTVQGGVIHFRGAIVEPLCDISTHAENIDLTCLREGKKQMHRIDLRQASGLPQDIQSIATVRLHYLDAQKSLAVMNIEYR
What are the official names of this protein?
Uncharacterized protein YmdA.
What is the protein family that this protein belongs to?
To the N-terminal of the FimA/PapA family of fimbria proteins.
Protein: ACTP5_ACTEQ
Sequence: MSRLIIVFIVVTMICAATALSSKKSINEDEKDEKRSVAVAGAVIEGATLTFNVLQTVLKALGDISRKIAVGIDNESGMTWTAMNTYFRSGTSDVILPHTVPHGKALLYNGQKDRGPVATGVVGVLAYAMSDGNTLAVLFSIPFDYNLYSNWWNVKVYKGHRRADQRMYEELYYNLSPFRGDNGWHNRDLGYGLKGRGFMNSSGQSILEIHVTKA
What is the function of this protein?
Pore-forming protein that forms cations-selective hydrophilic pores of around 1 nm and causes cytolysis.  Pore formation is a multi-step process that involves specific recognition of membrane sphingomyelin (but neither cholesterol nor phosphatidylcholine) using aromatic rich region and adjacent phosphocholine (POC) binding site, firm binding to the membrane (mainly driven by hydrophobic interactions) accompanied by the transfer of the N-terminal region to the lipid-water interface and finally pore formation after oligomerization of monomers.
What are the official names of this protein?
DELTA-actitoxin-Aeq1b, DELTA-AITX-Aeq1b, Equinatoxin V, Eqt V, EqtV, Equinatoxin-5.
What is the protein family that this protein belongs to?
Belongs to the actinoporin family. Sea anemone subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst. Target cell membrane. Note=Forms an alpha-helical membrane channel in the prey.
Protein: GATA_OLEA2
Sequence: MAQIYAQTLTETAAALAQGTLTAEEAVRACIDRIEATEPAVHALLATRCEEALAEARAMDAAGYDPAKPLWGVPVTVKDVLSTSGVATTCGSRILENYVPFFDAAAVSRLKDAGAVILAKTNMDEFAMGSSTEKSAFKTTHNPWDLQRVPGGSSGGSAASVAAGQCFASLGTDTGGSVRQPASFCGCVGLKPTYGRVSRYGLVAYGSSLDQIGPVTRSVEDAARVLAVIAGHDARDTTCSDRPVDDYLAALGSRSDLAGLRIGVPAEYWGEGLSGEVDSCCREALKKAEELGATLVDISLPNSRHAIAVYYIVAMAEASSNLARFDGVRFGHRSDNAASLPELYINSRSEGFGDEVQRRIMLGTYVLSSGYYDAYYRKAAQVRRLILQDFEKAFEQCDVICGPASPVTAWKHGAMSGDPLTMYLLDIFTISLNLAGLPGLSLPVGTGTESGMPVGLQILGKAFDEATLLSVAHVLEQRIGRTPVAQI
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: RECA_WOLWR
Sequence: MASNPEERNSDKQKALDNAISQIEKAFGKGAIMKLKQNPVEKIDTISTGSIALDSALGVGGLPKGRIIEIFGPESSGKTTLALHVIAEAQKKGGSCAFIDAEHALDVLYARKLGVSTDDLVISQPDTGEQALHIVEYLVCSGAVDVIVIDSVAALTPRAEIEGDMGDQHMGLQARLLSHGLRKLTSAVSKANCILIFINQIRMKIGVVYGNPETTTGGNALKFYTSVRLDIRKIGVIKDKENITGNETRVKVVKNKVAPPFREAKFDIMYNEGISKLGEIIDMGAKLGVLEKAGAYYSYNNTRLGQGRENVKTYLKTNKEVANEIETKIRDLLRNHDNSIIIDEDSEQLLEESVF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NSP6_ROTH3
Sequence: MNHLQQRQLFLENLLVGVNNTFHQMQKRSVSTCCQSLQKILDHLILLQTIHSPVFRLDRMQLRQMQTLACLWIH
What are the official names of this protein?
Non-structural protein 6, NSP6.
What is the protein family that this protein belongs to?
Belongs to the rotavirus A NSP6 family.
What are the subcellular locations of this protein?
Host cytoplasm. Host mitochondrion. Note=Found in spherical cytoplasmic structures, called viral factories, that appear early after infection and are the site of viral replication and packaging.
Protein: HEAT1_HUMAN
Sequence: MTSLAQQLQRLALPQSDASLLSRDEVASLLFDPKEAATIDRDTAFAIGCTGLEELLGIDPSFEQFEAPLFSQLAKTLERSVQTKAVNKQLDENISLFLIHLSPYFLLKPAQKCLEWLIHRFHIHLYNQDSLIACVLPYHETRIFVRVIQLLKINNSKHRWFWLLPVKQSGVPLAKGTLITHCYKDLGFMDFICSLVTKSVKVFAEYPGSSAQLRVLLAFYASTIVSALVAAEDVSDNIIAKLFPYIQKGLKSSLPDYRAATYMIICQISVKVTMENTFVNSLASQIIKTLTKIPSLIKDGLSCLIVLLQRQKPESLGKKPFPHLCNVPDLITILHGISETYDVSPLLHYMLPHLVVSIIHHVTGEETEGMDGQIYKRHLEAILTKISLKNNLDHLLASLLFEEYISYSSQEEMDSNKVSLLNEQFLPLIRLLESKYPRTLDVVLEEHLKEIADLKKQELFHQFVSLSTSGGKYQFLADSDTSLMLSLNHPLAPVRILAMNHLKKIMKTSKEGVDESFIKEAVLARLGDDNIDVVLSAISAFEIFKEHFSSEVTISNLLNLFQRAELSKNGEWYEVLKIAADILIKEEILSENDQLSNQVVVCLLPFMVINNDDTESAEMKIAIYLSKSGICSLHPLLRGWEEALENVIKSTKPGKLIGVANQKMIELLADNINLGDPSSMLKMVEDLISVGEEESFNLKQKVTFHVILSVLVSCCSSLKETHFPFAIRVFSLLQKKIKKLESVITAVEIPSEWHIELMLDRGIPVELWAHYVEELNSTQRVAVEDSVFLVFSLKKFIYALKAPKSFPKGDIWWNPEQLKEDSRDYLHLLIGLFEMMLNGADAVHFRVLMKLFIKVHLEDVFQLFKFCSVLWTYGSSLSNPLNCSVKTVLQTQALYVGCAMLSSQKTQCKHQLASISSPVVTSLLINLGSPVKEVRRAAIQCLQALSGVASPFYLIIDHLISKAEEITSDAAYVIQDLATLFEELQREKKLKSHQKLSETLKNLLSCVYSCPSYIAKDLMKVLQGVNGEMVLSQLLPMAEQLLEKIQKEPTAVLKDEAMVLHLTLGKYNEFSVSLLNEDPKSLDIFIKAVHTTKELYAGMPTIQITALEKITKPFFAAISDEKVQQKLLRMLFDLLVNCKNSHCAQTVSSVFKGISVNAEQVRIELEPPDKAKPLGTVQQKRRQKMQQKKSQDLESVQEVGGSYWQRVTLILELLQHKKKLRSPQILVPTLFNLLSRCLEPLPQEQGNMEYTKQLILSCLLNICQKLSPDGGKIPKDILDEEKFNVELIVQCIRLSEMPQTHHHALLLLGTVAGIFPDKVLHNIMSIFTFMGANVMRLDDTYSFQVINKTVKMVIPALIQSDSGDSIEVSRNVEEIVVKIISVFVDALPHVPEHRRLPILVQLVDTLGAEKFLWILLILLFEQYVTKTVLAAAYGEKDAILEADTEFWFSVCCEFSVQHQIQSLMNILQYLLKLPEEKEETIPKAVSFNKSESQEEMLQVFNVETHTSKQLRHFKFLSVSFMSQLLSSNNFLKKVVESGGPEILKGLEERLLETVLGYISAVAQSMERNADKLTVKFWRALLSKAYDLLDKVNALLPTETFIPVIRGLVGNPLPSVRRKALDLLNNKLQQNISWKKTIVTRFLKLVPDLLAIVQRKKKEGEEEQAINRQTALYTLKLLCKNFGAENPDPFVPVLNTAVKLIAPERKEEKNVLGSALLCIAEVTSTLEALAIPQLPSLMPSLLTTMKNTSELVSSEVYLLSALAALQKVVETLPHFISPYLEGILSQVIHLEKITSEMGSASQANIRLTSLKKTLATTLAPRVLLPAIKKTYKQIEKNWKNHMGPFMSILQEHIGVMKKEELTSHQSQLTAFFLEALDFRAQHSENDLEEVGKTENCIIDCLVAMVVKLSEVTFRPLFFKLFDWAKTEDAPKDRLLTFYNLADCIAEKLKGLFTLFAGHLVKPFADTLNQVNISKTDEAFFDSENDPEKCCLLLQFILNCLYKIFLFDTQHFISKERAEALMMPLVDQLENRLGGEEKFQERVTKHLIPCIAQFSVAMADDSLWKPLNYQILLKTRDSSPKVRFAALITVLALAEKLKENYIVLLPESIPFLAELMEDECEEVEHQCQKTIQQLETVLGEPLQSYF
What is the function of this protein?
Ribosome biogenesis factor.  Involved in nucleolar processing of pre-18S ribosomal RNA.  Required for optimal pre-ribosomal RNA transcription by RNA polymerase I (PubMed:17699751).  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797).
What are the official names of this protein?
HEAT repeat-containing protein 1, Protein BAP28, U3 small nucleolar RNA-associated protein 10 homolog.
What is the protein family that this protein belongs to?
Belongs to the HEATR1/UTP10 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: NEP1_NEPDI
Sequence: IGPSGVETTVYAGDGEYLMXLSIGTPAQPFSAIMDTGSDLIWTQXQPXTQXFXQSDPQGSSSFSTLPCGYGDSETQGSMGTETFTFGSVSIPNITFGXGEGPLPLPXQLDVAKYITLDLPIDPSAFDLCFQTPSDPSNLQIPTFVMHFDTGNSVVSFVSAQCGA
What is the function of this protein?
Extracellular proteinase found in the pitcher fluid of carnivorous plants.  Digest prey for nitrogen uptake.
What are the official names of this protein?
Aspartic proteinase nepenthesin-1, Nepenthesin-I.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted.