PharMolix/UniProtQA huggingface dataset:
Protein: Y5401_FRAAA
Sequence: MTSTRHDGDTWDLASSVGATATMAAVARAIATRADRRLIDDPFAAPLVRAVGIDLLTRLATGDVPPDGLVEQVAIDVAKVRARFYDEFFLEATNTGITQVVILASGLDSRAYRLPWPIGTVVYELDQPRVVEFKTRTLAALGAVPTADRRVAAVDLRDDWPAALRAAGFDPARPTAWSAEGLLGYLPPEAQDRLLDTVTELSAPESRVATENRPNPKPGDEDRTKEALNRISERWRAHSFDPDMARLRYYGERNETAPYLADRGWALTGISVRDLLAAHGLPPLRDDDLRMGDVRYVSGVRNKTTK
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase FRAAL5401.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: CH10_PASMU
Sequence: MNIRPLHDRVIIKREEVETRSAGGIVLTGSAATKSTRAKVLAVGKGRILENGTVQPLDVKVGDTVIFNDGYGVKAEKIDGEEVLIISENDILAIVE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EF1A_CAEEL
Sequence: MGKEKVHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGITIDIALWKFETAKYYITIIDAPGHRDFIKNMITGTSQADCAVLVVACGTGEFEAGISKNGQTREHALLAQTLGVKQLIVACNKMDSTEPPFSEARFTEITNEVSGFIKKIGYNPKAVPFVPISGFNGDNMLEVSSNMPWFKGWAVERKEGNASGKTLLEALDSIIPPQRPTDRPLRLPLQDVYKIGGIGTVPVGRVETGIIKPGMVVTFAPQNVTTEVKSVEMHHESLPEAVPGDNVGFNVKNVSVKDIRRGSVCSDSKQDPAKEARTFHAQVIIMNHPGQISNGYTPVLDCHTAHIACKFNELKEKVDRRTGKKVEDFPKFLKSGDAGIVELIPTKPLCVESFTDYAPLGRFAVRDMRQTVAVGVIKSVEKSDGSSGKVTKSAQKAAPKKK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha, EF-1-alpha.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_HELMI
Sequence: MFAIIETGGKQYKVQQGDVLKVEKLEANPGDVVEIDRVFAVSKDGELKVGAPTVEGAKVLLKVEDHGKGKKIIIFKYKPKKNYRRKQGHRQAFTQVRVEAIQA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: ELFA_ECO57
Sequence: MITMKKSVLTAFITVVCATSSVMAADDNAITDGSVTFNGKVIAPACTLVAATKDSVVTLPDVSATKLQTNGQVSGVQTDVPIELKDCDTTVTKNATFTFNGTADTTQITAFANQASSDAATNVALQMYMNDGTTAIKPDTETGNILLQDGDQTLTFKVDYIATGKATSGNVNAVTNFHINYY
What is the function of this protein?
Part of the elfADCG fimbrial operon, which could be required for adherence to host epithelial cells.  ElfA is an accessory colonization factor that contributes to adherence of bacteria to human intestinal epithelial cells and to animal intestinal tissue in vitro.  Binds specifically to laminin, but not to fibronectin or collagen type IV.
What are the official names of this protein?
Laminin-binding fimbrial subunit ElfA, ELF.
What is the protein family that this protein belongs to?
Belongs to the fimbrial protein family.
What are the subcellular locations of this protein?
Fimbrium.
Protein: Y1183_PHOLL
Sequence: MNLQHHFLIAMPSLSDPYFKRSVVYICEHNANGAMGLVINKPIEQISVRKVLQKLKISPEDRDESVNLNKPVMTGGPLAEDHGFILHTPKPGFSSSIKISDDTMITTSKDVLETLGTPRQPKQILVTLGYTSWEKGQLEKEIMENSWLTTNADPHIIFNSPIADRWREAASLLGINIYNIAPQAGHA
What are the official names of this protein?
UPF0301 protein plu1183.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: RL14_PECCP
Sequence: MIQEQTMLNVADNSGARRVMCIKVLGGSHRRYAGVGDIIKITIKEAIPRGKVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVILNNNSEQPIGTRIFGPVTRELRNEKFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: GLGC_THENN
Sequence: MGNVVAMILAGGQGTRLGVLTERIAKPAVPFGGKYRLIDFTLSNCVNSGIYRVGVLTQYRPHVLAKHIGIGRPWDLDRKDGGVEILPPYVGRNESDWYKGTANAVYQNLEFLEENDAELVLVLSGDHVYAMNYNDLIDYHLLKGADGTIACMEVPLEEASRFGIMITDVEGRIVDFEEKPPKPRSNLASLGIYVFNYEFLKRVLIEDENDPNSSHDFGKDVIPKILRENKGSLYAFRFDGYWRDVGTIRSYWEANLELVLPVPPFNLYDPNWRFFTHSEEMPPAYVAPEARTSTSLISEGAEVYGEVTNSVIFQGVRIGKGTVVKNSVIMTRTEIGENCYLENVIVAENVKIGNNVKMGVGEDAKSKLDPKIYTGLLTVVGMNSTIPDDVVIGKNCVIGVGVKPEDFKTKKLESGDFVLPREE
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: PVK1_KARBI
Sequence: EAAGLLPFPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
CAPA-Periviscerokinin-1, CAPA-PVK-1.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y4007_SERP5
Sequence: MDYEFLRDVTGQVIVRFSMGHEVIGHWINEELKGDFNLLDRIEAGAAEVKGSERQWQLEGHEYTLLMDGEEVMIRANLLEFEGEEMEEGMNYYDEESLSFCGVEDFLQVLKAYRSFMLKY
What are the official names of this protein?
UPF0231 protein Spro_4007.
What is the protein family that this protein belongs to?
Belongs to the UPF0231 family.
Protein: CD37_HUMAN
Sequence: MSAQESCLSLIKYFLFVFNLFFFVLGSLIFCFGIWILIDKTSFVSFVGLAFVPLQIWSKVLAISGIFTMGIALLGCVGALKELRCLLGLYFGMLLLLFATQITLGILISTQRAQLERSLRDVVEKTIQKYGTNPEETAAEESWDYVQFQLRCCGWHYPQDWFQVLILRGNGSEAHRVPCSCYNLSATNDSTILDKVILPQLSRLGHLARSRHSADICAVPAESHIYREGCAQGLQKWLHNNLISIVGICLGVGLLELGFMTLSIFLCRNLDHVYNRLARYR
What are the official names of this protein?
Leukocyte antigen CD37, Tetraspanin-26, Tspan-26.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SYP_ACIF5
Sequence: MRASQIFIPTLKETPAEAELVSHQLLLRGGFIRRLASGLYTWMPLGLRVLRKVERVVREEMDRSGAQELLMPVVQPAELWQESGRWEQYGPELLRLRDRHDREFCLGPTHEEVISDLARREIHSYRQLPVNFYQIQTKFRDEIRPRFGLMRGREFIMKDAYSFHMDHSSLEITYQAMYEAYQRVFTRLGLSFRAVEADNGAIGGKRSHEFHVLADSGEDAIVSCHHCDYAANMEKAASRPDLAETEIPLAAERVRTPGIRTVAEQAEHLGIPTAKIVKTVLVVADGKTVMLLLRGDDELNLVKAGHALNAQDVQMARPEEAISATGAPLGFIGPKEPLLSIPILADHRALGVANFSTGANAADLHWINLNWDRDLPRPAAADLRNVRAGDACPHCAEGTLSIRRGIEVGHVFQLGERYSESMGITVLDETGRDATVTMGCYGIGVSRVVAAAVEQHFDDRGIIWPVALAPFEVGIVAINARKSPDVAAAAQALHDRLEAEGYSVLLDDRDERPGVQFATMDLVGLPHRIVVSDTVLAQGVWEYRARRTTENVLLDETQLMERLRKEHARG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3579_MYCTU
Sequence: MPGNSRRRGAVRKSGTKKGAGVGSGGQRRRGLEGRGPTPPAHLRPHHPAAKRARAQPRRPVKRADETETVLGRNPVLECLRAGVPATALYVALGTEADERLTECVARAADSGIAIVELLRADLDRMTANHLHQGIALQVPPYNYAHPDDLLAAALDQPPALLVALDNLSDPRNLGAIVRSVAAFGGHGVLIPQRRSASVTAVAWRTSAGAAARIPVARATNLTRTLKGWADRGVRVIGLDAGGGTALDDVDGTDSLVVVVGSEGKGLSRLVRQNCDEVVSIPMAAQAESLNASVAAGVVLAEIARQRRRPREPREQTQNRMI
What are the official names of this protein?
Uncharacterized tRNA/rRNA methyltransferase Rv3579c.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
Protein: GATZ_ECO24
Sequence: MKTLIARHKAGEHIGICSVCSAHPLVIEAALAFDRNSTRKVLIEATSNQVNQFGGYTGMTPADFREFVFTIADKVGFARERIILGGDHLGPNCWQQENADAAMEKSVELVKEYVRAGFSKIHLDASMSCAGDPIPLAPETVAERAAVLCFAAESVATDCQREQLSYVIGTEVPVPGGEASAIQSVHITHVEDAANTLRTHQKAFIARGLTEALTRVIAIVVQPGVEFDHSNIIHYQPQEAQPLAQWIENTRMVYEAHSTDYQTRTAYWELVRDHFAILKVGPALTFALREAIFALAQIEQELIAPENRSGCLAVIEEVMLDEPQYWKKYYRTGFNDSLLDIRYSLSDRIRYYWPHSRIKNSVETMMVNLEGVDIPLGMISQYLPKQFERIQSGELSAIPHQLIMDKIYDVLRAYRYGCAE
What is the function of this protein?
Component of the tagatose-1,6-bisphosphate aldolase GatYZ that is required for full activity and stability of the Y subunit.  Could have a chaperone-like function for the proper and stable folding of GatY.  When expressed alone, GatZ does not show any aldolase activity.  Is involved in the catabolism of galactitol.
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit GatZ.
What is the protein family that this protein belongs to?
Belongs to the GatZ/KbaZ family. GatZ subfamily.
Protein: ENGB_STRP2
Sequence: MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINTMLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYLTTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESAIKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: RRF_WOLSU
Sequence: MELNEVYQYTKEHMEKTIDAMKRDFATLRTGKVSTAIVEPIRVDYYGTPTPLSQVGSVIASDATTLVISPWEKNLLKGIEKAIQEANIGVNPNNDGDVIKLFFPPMTSEQRKEIAKDAKALGEKAKVAVRNIRKESNDKIKKLEKDKLITEDQSKKAHDEVQKYTDDYVKKIDDMVKSKEEEILKV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_FRATO
Sequence: MSLENKNIIITAGGTGGHIYPALAIAELLRQNKANVTWVGTPNSMEASIVPEYFNIQFIKSSGVRRKGIIKKITFPLKLAYNTLKSRSLLKKLKANLVIGFGGYVSGPICLAAAQINIPVIIHEQNAKIGLTNRILAKFATTICLAFEIENLHKQFSSKQLAKTKIVGNPVRKDIVALNDKARIYTDSSTLKILVLGGSQGAKAINEIIPKLIQKSNEQGINIKVWHQTGKLSLEETKDAYKDISQNHIKDIAAFIDDMAIAYNWADLVICRAGALTVSECAIAGLPAIFIPLPSAVDDHQFFNAQNIVNNNAGFCLRQQQMTLENLLAIIKPLNQDRSKLEQMSKMAKKTLIKNSSEQILDCVKKILNNK
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TIG_MESH7
Sequence: MIKREFLPESAELKIKLTADSKKWAEFYQKAEQKQAAKVSLRGFRKGKVPLEKARAYLNPQAVFELALRMFLPELEKQAATNIIDSDNVIESPIFNIVNMDKNNLEIEFLYPVYPEIKLPDYKNLKTKFAIKKITKEDIELQKQKLLEAKGRFIEVNRPVKIGDVINFNFKGFIDDEPFDGGEGENFDLRIGSNSFIAGFEEQLVGLEIKKEADIYVTFPENYQVHTYANKKARFRVKINKIKENKPAKLTNEFVASLKIQNVETISQLEVYLENLTERENIERAKIDFQKNALTEIGEQVEVPLAKKLINLEIERLNEVFHSTLKQQEIPLKEYLKITKFTEKDIYDQFEVEAKKLLKNSFIFAEIAKLEGLVPTQQEYESHVEKLAKFTGKSVQEISETVSYNEIQINITNQKVIDKLIEFNHEAKDEEIVNKNQNDNEI
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: COA3_PICST
Sequence: MAVIGAPKGHDRYRDPKTHQMTPALYRVRAPFFWKNTIGLAICTAIPLGVYMYTLHMLSKDEFGDIPIPPISDTELTKLKKEYEASKNQN
What is the function of this protein?
Required for assembly of cytochrome c oxidase (complex IV).
What are the official names of this protein?
Cytochrome c oxidase assembly factor 3, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the COA3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: RLMH_BRUAB
Sequence: MRVSVFAVGRMKSGPERELVERYFDRFAKAGPPLGLEFAGVSEIPESRGQTAQLRKAEEAQRIHEALDNAKSGGTSSGGAALILLDERGKTLGSEAFAAIVGRMRDDGKRQLIVAIGGPDGHDPALRSRADLVLALGELTWPHQIARILIAEQLYRAATILAGHPYHRS
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LITD_LATHA
Sequence: DEEDGEMTLEERFSEWSEPXTVQGAVDEAEALLIEKINHXXDVNAKDNLTPLHSAAKTALHAINDDLDMVR
What is the function of this protein?
Insecticidal presynaptic neurotoxin that induces massive neurotransmitter release at insect (but not vertebrate) neuromuscular junctions.  Native toxin forms cation-permeable pores (with high permeability to calcium) in lipid membranes locust muscle membrane and artificial lipid bilayers (By similarity).  May bind to insect neurexin-1 homolog, insect adhesion G protein-coupled receptor L1 homolog, and insect receptor-type tyrosine-protein phosphatase S homolog, and induces neurotransmitter exocytosis both by forming tetrameric pores in membranes and signaling via G protein-coupled receptor (By similarity).  Oligomerization is a process independent of divalent cations (By similarity).
What are the official names of this protein?
Delta-latroinsectotoxin-Lh1a, Delta-LIT-Lh1a, Delta-latroinsectotoxin, Delta-LIT.
What is the protein family that this protein belongs to?
Belongs to the cationic peptide 01 (latrotoxin) family. 04 (delta-latroinsectotoxin) subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Forms a membrane channel in the prey.
Protein: MANI_MARM1
Sequence: MSYPAFDSKTFLEAHIEKTMAFYFPTCIDPEGGFFQFFKDDGSVYDPNTRHLVSSTRFIFNFAQAYLHTNIAEYKHAAVHGIQYLRQRHQSQSGGYVWLLDGGTNLDETNHCYGLAFVILAYSNALQIGLSEAEVWIEVTYDLLETHFWENKHGLYLDEISSDWKTVSPYRGQNANMHMCEALMSAFDATQNPKYLDRAKLLAKNICQKQASLSNSNEVWEHYTNDWQIDWDYNKNDPKHLFRPWGFQPGHQTEWAKLLLMLDKRSPENWYLPKAKYLFDLAYKKAWDTKKGGLHYGYAPDGTVCDPDKYFWVQAESFAAAWLLYKATKDETYYKQYLTLWEFSWNHMIDHTFGAWYRILDENNAQYDNNKSPAGKTDYHTMGACYEVLKTLTL
What is the function of this protein?
Catalyzes the reversible isomerization of D-mannose to D-fructose.  Can also isomerize D-lyxose, with lower efficiency.  In longer reaction with a higher concentration of enzyme, it can isomerize 4-OH D-mannose derivatives (D-talose and 4-O-monosaccharyl-D-mannose).  Cannot use D-glucose.
What are the official names of this protein?
D-mannose isomerase, MI.
What is the protein family that this protein belongs to?
Belongs to the N-acylglucosamine 2-epimerase family.
Protein: KTHY_YERPN
Sequence: MNSKFIVIEGLEGAGKTTTRDTVVAVLRAQGINDIVFTREPGGTPLAEKLRDLIKQGIDGEVLTDKAEVLMLYAARVQLVENVIKPALARGSWVVGDRHDLSSQAYQGGGRGIDSQLMASLRDTVLGEFRPDLTLYLDLPPAVGLARARARGELDRIEQESLAFFERTRARYLELAASDASIKTIDASQPIEQVSASISQALAQWLTNQEPV
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: MAMB6_DENVI
Sequence: RPSFCNLPVKPGPCSGFFSAFYYSQKTNKCHSFTYGGCRGPGNRFRTIEECRRTCVG
What is the function of this protein?
Interacts with vasopressin V2 receptor (V2R/AVPR2), probably in a selective manner (PubMed:35122240).  Inhibits vasopressin binding human V2R in the nanomolar range (Ki=21. 5 nM), and also moderately inhibits vasopressin-induced cAMP production (IC(50)=574 nM).  In vivo, intraperitoneal injection of this protein into rats increases diuresis by 2-fold, without any loss of electrolytes (PubMed:35122240).
What are the official names of this protein?
Mambaquaretin-6, MQ6, Upsilon-Dv2d.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
Protein: Y1595_HAEIN
Sequence: MIKQITERFTPRQYLAEFLLGLTALFGLYLIVAWSSYTPLDNSWATVSAYGNTINKVGSFGAWIIDLFFVFLGYVAHIIPFTAFLVPIYLLKTKAVKQLSCTRIILR
What are the official names of this protein?
Uncharacterized protein HI_1595.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EMC2_YEAST
Sequence: MLKDLVREKLLTIMNTKAYTQFNPEQLLQLENEMKIYMKSGDSALTEGNYFFLMEMLFYVLVYRNQDVDAQVVYNTLRDRLGENSYKMVIMKATLLQINGNDKGAIEYLENLLNDDLEYETDFVTYVSIAKKLIAIKTTSKNLSQESVLKEVVALTDKFPLDAELWWYASEIYFEMGQFEKACYCLEQVLCITPFNYACFGRLSETLYYEALRSKKQTKTELLEKALKNALRSVELSELYLKGWALVNIISRELGRNKQNDLIKLSASKLKEISAKSNNKDKITAELILNKI
What is the function of this protein?
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins (PubMed:29809151).  Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues (PubMed:29809151).  Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices (PubMed:29809151).  It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes.  By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins (By similarity).
What are the official names of this protein?
ER membrane protein complex subunit 2.
What is the protein family that this protein belongs to?
Belongs to the EMC2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: 5052R_ASFB7
Sequence: MFSLQDLCRKHLFILPDVFGEHVLQRLGLYWRCHGSLQRIGDDHILIRRDLILSTNEALRMAGEEGNNEVVKLLLLWKGNLHYAVIGALQGDQYDLIHKYENQIGDFHFILPLIQDANTFEKCHALERFCGVSCLLKHATKYNMLPILQKYQEELSMRAYLHETLFELACLWQRYDVLKWIEQTMHVYDLKIMFNIAISKRDLTMYSLGYIFLFDRGNTEATLLTQHLEKTAAKGLLHFVLETLKYGGNIDTVLTQAVKYNHRKLLDYFLRQLPRKHIEKLLLLAVQEKASKKTLNLLLSHLNYSVKRIKKLLRYVIEYESTLVIKILLKKRVNLIDAMLEKMVRYFSATKVRTIMDELSISPERVIKMAIQKMRTDIVIHTSYVWEDDLERLTRLKNMVYTIKYEHGKKMLIKVMHGIYKNLLYGEREKVMFHLAKLYVAQNAATQFRDICKDCYKLDVARFKPRFKQLILDCLEIVTKNLAIVSWKS
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 505-2R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 505 family.
Protein: F210A_CHICK
Sequence: MQRSVLHTASQLAHGMCLLFPRTGAFRGLKGPSVSSNVGCKVILALDPPKRCLHAGAALFASKSSAVSSQPADTPRKVPEEREPLTSATEVPKQSPVESDASDPDPLQDKSISLVQRFKKTFKQYGKVMIPVHLVTSTVWFGSFYYAAMKGVNVVPFLELIGLPDSIVDILKNSQSGNALTAYALYKIATPARYTVTLGGTSITVKYLRKNGYMSTPPPVKEYLQDRMEETKDKITEKMEETKDKITEKMEETKDKITEKIQETKDKVSFKKIKD
What is the function of this protein?
May play a role in the structure and strength of both muscle and bone.
What are the official names of this protein?
Protein FAM210A.
What is the protein family that this protein belongs to?
Belongs to the FAM210 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Mitochondrion. Cytoplasm.
Protein: YCF22_NEOYE
Sequence: MRTRYKNTYKEFLGACFLGSVTLLSISLWNIINQAGKNHSYKAFIEFDSAYGIQEGTAVRLRGLPVGKVVGISQSSNSILTSIEIKSSSTIIPKTSLIETNQTGLLNDTVIDIIPLSKLSIDYSSIKAGPLSGACDNSQIICNLNYLKGERGLNYDDLIRATTRISQRFDDPKLFYGLYYLIGNMIKLSNNFVDLTEQIAYMSLFIRLQLENLKEQ
What are the official names of this protein?
Uncharacterized protein ycf22.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DUS18_PONAB
Sequence: MTAPSCAFPVQFRQPSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNTLYEDIQYLQVPVADAPDSRLCDFFDPVADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLLDAHTWTKSCRPIIRPNSGFWEQLIHYEFQLFGKNTVHMVSSPMGMIPDIYEKEVRLMIPL
What is the function of this protein?
Can dephosphorylate single and diphosphorylated synthetic MAPK peptides, with preference for the phosphotyrosine and diphosphorylated forms over phosphothreonine.  In vitro, dephosphorylates p-nitrophenyl phosphate (pNPP).
What are the official names of this protein?
Dual specificity protein phosphatase 18.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Note=Translocates to cytoplasm in response to apoptotic stimuli such as staurosporine treatment.
Protein: MDTA_ECOBW
Sequence: MKGSYKSRWVIVIVVVIAAIAAFWFWQGRNDSRSAAPGATKQAQQSPAGGRRGMRSGPLAPVQAATAVEQAVPRYLTGLGTITAANTVTVRSRVDGQLIALHFQEGQQVKAGDLLAEIDPSQFKVALAQAQGQLAKDKATLANARRDLARYQQLAKTNLVSRQELDAQQALVSETEGTIKADEASVASAQLQLDWSRITAPVDGRVGLKQVDVGNQISSGDTTGIVVITQTHPIDLVFTLPESDIATVVQAQKAGKPLVVEAWDRTNSKKLSEGTLLSLDNQIDATTGTIKVKARFNNQDDALFPNQFVNARMLVDTEQNAVVIPTAALQMGNEGHFVWVLNSENKVSKHLVTPGIQDSQKVVIRAGISAGDRVVTDGIDRLTEGAKVEVVEAQSATTPEEKATSREYAKKGARS
What is the function of this protein?
The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate.
What are the official names of this protein?
Multidrug resistance protein MdtA, Multidrug transporter MdtA.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.