PharMolix/UniProtQA huggingface dataset:
Protein: POLS_EEEV1
Sequence: MFPYPTLNYSPMAPVNPMAYRDPNPPRRRWRPFRPPLAAQIEDLRRSIANLTFKQRAPNPPAGPPAKRKKPAPKPKPAAPKKKRQPPPAKKQKRKQKPGKRQRMCMKLESDKTFPILLNGQVNGYACVVGGRVFKPLHVEGKIDNEQLAAIKLKKASIYDLEYGDVPQCMKSDTLQYTSEKPPGFYNWHHGAVQYENNRFTVPRGVGGKGDSGRPILDNRGRVVAIVLGGANEGSRTALSVVTWNQKGVTVKDTPEGSEPWSLTTVMCVLANITFPCDQPPCMPCCYEKNPHETLTMLEQNYDSQAYDQLLEAAVKCNSRRTRRDLETHFTQYKLARPYIADCSNCGHGRCDSPIAIEDVRGNAHAGYIRIQTSAMFGLKSDGVDLAYMSFMNGKTLKAIKIEHLYARTSAPCSLVSYHGYYLLAQCPPGDTVTVGFQDGANKHMCTIAHKVEFRPVGREKYRHPPAHGVELPCNKYTHKRADQGHYVEMHQPGLVADHSLLSLSSTKVKITVPSGSQVKYYCKCPDVQEGTTSGDHTTTCTDLKQCRAYLIDNKKWVFNSGKLPRGEGETFKGKLHVPFVPVTSKCTATLAPEPLVEHKHRSLILHLHPEHPTLLTTRALGNDARPTRQWVDQPTTVNFTVTGEGFEYTWGNHPPKRVWAQESGEGNPHGWPHEVVIYYYNRYPMTTIVGLCTCAAIIMVSCITSVWLLCRTRNLCITPYRLAPNAQVPILLAVLCCVKPTRADDTLQVLNYLWNNNQNFFWMQTLIPLAALIVCMRMLRCLLCCGPAFLLVCGALGAAAYEHTAVMPNKVGIPYKALVERPGYAPVHLQIQLVTTKIIPSANLEYITCKYKTKVPSPVVKCCGATQCTSKQHPDYQCQVFAGVYPFMWGGAYCFCDTENTQMSEAYIERAEECSVDQAKAYKVHTGTVQAVVNITYGSVSWRSADVYVNGETPAKIGDAKLTIGPLSSAWTPFDSKVVVYGHEVYNYDFPEYGTGKAGSFGDLQSRTLTSNDLYANTNLKLQRPQPGVVHTPYTQAPSGFERWKKDRGAPLNDIAPFGCTIALDPLRAENCAVGNIPLSIDIPDAAFTRISETPTVSDLECKITECTYASDFGGIATVAYKASKAGNCPIHSPSGIAVIKENDVTLADSGSFTFHFSTASIHPAFKMQICTSVVTCKGDCKPPKDHIVDYPAQHTETFTSAVSATAWSWLKVLVGSTSAFIVLGLIATAVVALVLFTHKH
What is the function of this protein?
Class II viral fusion protein.  Fusion activity is inactive as long as E1 is bound to E2 in mature virion.  After virus attachment to target cell and endocytosis, acidification of the endosome would induce dissociation of E1/E2 heterodimer and concomitant trimerization of the E1 subunits.  This E1 trimer is fusion active, and promotes release of viral nucleocapsid in cytoplasm after endosome and viral membrane fusion.  Efficient fusion requires the presence of cholesterol and sphingolipid in the target membrane.  Fusion is optimal at levels of about 1 molecule of cholesterol per 2 molecules of phospholipids, and is specific for sterols containing a 3-beta-hydroxyl group.
What are the official names of this protein?
Structural polyprotein, p130.
What are the subcellular locations of this protein?
[Capsid protein]: Virion. Host cytoplasm. Host cell membrane. Host nucleus. SUBCELLULAR LOCATION: [Spike glycoprotein E2]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [6K protein]: Host cell membrane; Multi-pass membrane protein. Virion membrane; Multi- pass membrane protein. SUBCELLULAR LOCATION: [Spike glycoprotein E1]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein.
Protein: MAO2_HAEIN
Sequence: MTEQLRQAALDFHEFPIPGKIEVTPTKSLATQRDLALAYSPGVAEPCLEIEKDPAASYKYTARGNLVAVISNGTAVLGLGNIGALAGKPVMEGKGVLFKKFAGINVFDIEVNEHDPDKLVDIIASLEPTFGGVNLEDIKAPECFYIEQKLRERMNIPVFHDDQHGTAIISAAAIINSLRIVGKKIEDVRLVASGAGAASIACLNLLLSLGMKRENITVCDSKGVVYKGRDDKMDQTKKEYAIEDNGWRKLADAIPNADIFLGCSAAGALTQDMVKSMAAHPIILALANPNPEITPPEAKAVRPDAIVCTGRSDYPNQVNNVLCFPFIFRGALDVGATTINEEMKRAAVYAIADLALEEQNEVVTSAYGGEGATFGADYVIPRPFDPRLIVRIAPAVAKAAMESGVATRPIQNWDAYVEKLTQFVYKTSLFMRPIFSQAKSAKQRIILAEGEENKALHATQEVISMGLANPILIGRRSVIEEKIKKLGLRLTAGVDFEIVDNEDNPRYEECWKHYYELTKRKGITPAIAKRVVRSNTTVLASTLLSLGYADALVCGLFGSYGKHLASIRDIIGLKDGVKTAAALNSLVLPTGNVFLTDTHVNSNPTAEELAEITLMAAEEIHRFGIEPAVALLSHSNFGSSDSLGAPKMREVLQIVKERNPHLMIDGEMRGDLAMNEAHRKELMPDSPLKGSANLLVFPDLSASRISYSLLRGTTTAITVGPILMGMNKSAHILNPGASVRRIINMIAYAAVKAQQE
What are the official names of this protein?
NADP-dependent malic enzyme, NADP-ME.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
Protein: FB259_ARATH
Sequence: MRIESLLQHDVVERILERLAVNSLPRFKAVSKQWKSTIESQFFQGKHLTHRQQSGDPVVLMVTVYNDDSPHVGSLLLGSRRTRNPTTLII
What are the official names of this protein?
Putative F-box protein At5g16285.
Protein: XKDW_BACSU
Sequence: MILYDAIMYKYPNAVSRKDFELRNDGNGSYIEKWNLRAPLPTQAELETWWEELQKNPPYEPPDQVELLAQELSQEKLARKQLEELNKTLGNELSDIKLSLLSLKGDYAE
What are the official names of this protein?
Phage-like element PBSX protein XkdW.
What is the protein family that this protein belongs to?
To B.subtilis YqcC.
Protein: LANLB_BACLI
Sequence: MKTMKNSAAREAFKGANHPAGMVSEEELKALVGGNDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC
What is the function of this protein?
Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria.  The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores.  When present individually, LchA2 exhibits activity towards B. subtilis L1 (IC(50)=30 uM), Rhodococcus sp.  SS2 (IC(50)=16. 6 uM), M. luteus B1314 (IC(50)=2. 6 uM), B. megaterium VKM41 (IC(50)=2 uM), S. aureus 209p (IC(50)=20 uM), B. pumilus 2001, B. globigii I, B. amyloliquefaciens I, M. smegmatis 1171 and M. phlei 1291.  However, when combined with LchA1, it displays much stronger activity against B. subtilis L1 (IC(50)=0. 64 uM), Rhodococcus sp.  SS2 (IC(50)=0. 64 uM), M. luteus B1314 (IC(50)=0. 09 uM), B. megaterium VKM41 (IC(50)=0. 12 uM) and S. aureus 209p (IC(50)=0. 64 uM).  The activity of the combined LchA1 and LchA2 peptides is strongest at a molar ratio of 1.  Even when applied at 17-fold concentration of the highest IC(50) values for Gram-positive bacteria, neither the individual nor the combined peptides display activity against Gram-negative bacteria P. aeruginosa PAO1, P. putida I-97 or E. coli C600.
What are the official names of this protein?
Lantibiotic lichenicidin VK21 A2, LchA2.
What are the subcellular locations of this protein?
Secreted.
Protein: ARGC_METLZ
Sequence: MDIAIIGASGYAGGDLIRLLLTHKEADIVCATSRKLAGTPVTKDHIHLKNLIDLEYTNPDVENIDADFAFLAVPHTAAMQYAGKLKERGIKTVDFSADYRLPREIYEKTYGVKHSDYFKAPYGIPELHRNEVKNASFVANPGCFPTGATLAAAPVAKLAHTIIYDSKSGVSGAGDSISETTHFPNVAENILPYKITAHRHLPEMRQEAAFLGSKANVYFTPHLLPAIRGIITTAHILFNEPMELEMIQKLYQDFYKNEPFVRLQPAKLGGVRGSNFCDINFELENDGTRLVAVSAIDNLVKGAAGQAVQNMNIMCGFDEAEGIRMPGMFP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POTA_STRPM
Sequence: MTKPIITFNNVSKTFEDSGTQVLKNINFDLEEGKFYTLLGASGSGKSTILNIMAGLLDASSGDIYLDGERINDLPINKRDIHTVFQNYALFPHMTVFENVAFALKLKKVDKKEIAKRVKETLKMVQLEGYENRSIQKLSGGQRQRVAIARAIINQPRVVLLDEPLSALDLKLRTEMQYELRELQQRLGITFVFVTHDQEEALAMSDWVFVMNEGEIVQSGTPVDIYDEPINHFVANFIGESNIINGTMIEDYLVSFNGKEFESVDGGMRPNEPVEVVIRPEDLQITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIEGEVIGLDFTPEDLHIMRLNETEEEFDARIEEYVEMDEPEDGLINAIEEERNEENL
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GPX4_CALJA
Sequence: MSLGRLCRLLKPALLCGALAAPGLAGTMCASQDDWRSARSMHEFSAKDIDGHTVNLDKYRGFVCIVTNVASQUGKTQVNYTQLVDLHARYAECGLRILAFPCNQFGKQEPGSNEEIKEFAAGYNVKFDMFSKICVNGDDAHPLWKWMKIQPKGKGTLGNAIKWNFTKFLVDKNGCVVKRYGPMEEPQVIEKDLPCYF
What is the function of this protein?
Essential antioxidant peroxidase that directly reduces phospholipid hydroperoxide even if they are incorporated in membranes and lipoproteins (By similarity).  Can also reduce fatty acid hydroperoxide, cholesterol hydroperoxide and thymine hydroperoxide (By similarity).  Plays a key role in protecting cells from oxidative damage by preventing membrane lipid peroxidation (By similarity).  Required to prevent cells from ferroptosis, a non-apoptotic cell death resulting from an iron-dependent accumulation of lipid reactive oxygen species (By similarity).  The presence of selenocysteine (Sec) versus Cys at the active site is essential for life: it provides resistance to overoxidation and prevents cells against ferroptosis (By similarity).  The presence of Sec at the active site is also essential for the survival of a specific type of parvalbumin-positive interneurons, thereby preventing against fatal epileptic seizures (By similarity).  May be required to protect cells from the toxicity of ingested lipid hydroperoxides (By similarity).  Required for normal sperm development and male fertility (By similarity).  Essential for maturation and survival of photoreceptor cells (By similarity).  Plays a role in a primary T-cell response to viral and parasitic infection by protecting T-cells from ferroptosis and by supporting T-cell expansion (By similarity).  Plays a role of glutathione peroxidase in platelets in the arachidonic acid metabolism (By similarity).  Reduces hydroperoxy ester lipids formed by a 15-lipoxygenase that may play a role as down-regulator of the cellular 15-lipoxygenase pathway (By similarity).
What are the official names of this protein?
Phospholipid hydroperoxide glutathione peroxidase, PHGPx, Glutathione peroxidase 4, GPx-4, GSHPx-4.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
What are the subcellular locations of this protein?
[Isoform Mitochondrial]: Mitochondrion. SUBCELLULAR LOCATION: [Isoform Cytoplasmic]: Cytoplasm.
Protein: PPR18_MACMU
Sequence: MATIPDWKLQLLARRRQEEASVRGREKAERERLSQMPAWKRGLLERRRAKLGLSPGEPSPVPGTAEAGPPDPDESSVLLEAIGPVHQNRFIRQERQQQQQQQQRSEELLAERKPVPLEARERRPSPGEMRDQSPKGRESREERLSPRETRERRLGIGGAQESSLRPLEARDWRQSPGEVGDRSSRLSEPWKWRLSPGETPERSLRLAESREQSPRRKEVESRLSPGESAYQKLGLTEAHKWRPDSRESQEQSLVQLEATEWRLRSGEERQGYSEKCGRKEEWPVPGVAPEETTELSETLTREAQGSSSTGMEAAEQRPVEDGERGMKPAEGWKWTLNSGKAREWTPRDIEAQTQKPEPSESAEKRLESPSVEAGEGEAEKEEAGAQGRPLRALQNCCSVPSPLPPEDAGTGGLRQQEEEAVELQPPPPAPLSPPPPAPTAPQPPGDPLMSRLFYGVKAGPGVGAPRRSGHTFTVNPRRSVPPTTPATPTSPATADAAVPGAGKKRYPTAEEILVLGGYLRLSRSCLAKGSPERHHKQLKISFSETALETTYQYPSESSVLEELGPEPEVPSAPNPPAAQPDDEEDEEELLLLQPELQGGLRTKALIVDESCRR
What is the function of this protein?
May target protein phosphatase 1 to F-actin cytoskeleton.
What are the official names of this protein?
Phostensin, Protein phosphatase 1 F-actin cytoskeleton-targeting subunit, Protein phosphatase 1 regulatory subunit 18.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: NRTR_ACIAD
Sequence: MSLRVNFSSEQAFLAQYQKSDYPSPLMTVDMAIFSVDQGQLQILLIQRSNYPQKSYWALPGGFVDLEQDQNLMACAHRKLLEKTGIDSPYLEQVASIGNAKRDPRGWSVTVLYFALINFKAYQQQIQHSEHSEWVTLEQALKLDLAFDHHDLLQQAFARLNNKTRYTALPISLMPPLFTLTELQNIYEIILGHNLEKKAFRRRMIESGVVEETDQSKIAGKRPAQLYRFALQDYDFNFPRMLEYPRHHED
What is the function of this protein?
Involved in the transcriptional regulation of the nondeamidating salvage pathway for production of NAD from nicotinamide (PubMed:20926389).  Represses expression of the prs-nadV-nrtR operon by binding to the DNA region located upstream of the operon, thus blocking the nondeamidating pathway (PubMed:20926389).
What are the official names of this protein?
ADPR responsive transcriptional repressor NtrR, Nudix-related transcription repressor.
Protein: FADJ_VIBVY
Sequence: MSEQKAFNLKIDEQNIAWLGIDVPNEKMNTLQAAFADEMKAIFAQLKDSSGLKGLIVHSLKPDNFVAGADVRMLEACKTAPEAEALARQGQELFQQLSDLPYPVVAAIHGPCLGGGLELALACDFRVCSDDDATRLGLPEVQLGLLPGSGGTQRLPRLIGLLPSLDLILTGKQLRAKKAKKLGVVDACVPQTILLDVAKQFVEKGKKRAKQKVTTKEKLLSGSGLGRKFVFEQAAKKTHEKTRGNYPATVAILQVIQHGLEKGMKQGLELEAKRFGELVMSNESKALRSIFFATTEMKKETGSEAKPSKVGMVGVLGGGLMGAGISHVSVAKAKVPVRIKDVSNDGVLNALKYNYKLFDKQRKRRILSKAQLQSKMLQLSGGTDFTSFNRTDVVIEAVFEDLSLKQQMVADIEANAKPETIFATNTSSLPIHKIAEKAQRPENIVGLHYFSPVEKMPLVEVIPHESTSEETIATVVALAKKQGKTPIVVKDQAGFYVNRILAPYMNESAHILLANEPIDKIDTALLDFGFPVGPITLLDEVGVDIGAKIMPILVAELGARFKGPDVFDVLLNDGRKGRKSGKGFYTYKGKKKEVDKSVYKLLKLTPESKLSDNDIALRCVLPMLNEAVRCLDDGIIRSPRDGDIGAIFGIGFPPFLGGPFRYMDQFGLKELVEKMNQFAEKYGDRFAPCDGLLTRAGEGRRFYDN
What is the function of this protein?
Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA.  Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPB_LEPIN
Sequence: MSQPSKTQIALIGASGRMGRAIVSVLSTSVKSTLSSSVVSQSSVFLGMDSGLHSGIKQNGVNFSSDLEAAVRSADCVIDFSTHQNLDFTLKACIQYQKPVVIGITGLTELQKDALQVASKEIGIVYSPNMSIGVNLLFKLTEIAAKVMGEISDIEIQDIHHRHKKDAPSGTAEKLKSILLETLGRTSKNVVHGRHGILKERDSKEIGIHTFRAGEVIGDHTVYFFTPEERIEITHKAQDRKTFAVGSVHAAEFLVGRKPGLYDMFAVLGL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HISX_XANC5
Sequence: MKILDWSQLDGAARTDALTRPVQTVATQTRDAVAALIADVRARGDAALREITARFDGVSLESFAVSEADFAAAEAAVAPELRQAMQDAVARIDAFHRAGMSEGYAVETAPGVVCEKIVRPIGRVGLYVPAGSAPLPSTALMLGVPARLAGCREVVLCTPPRKDGSVDPAVLVAAQLTGVRRVFKLGGAQAIAAMAYGTESVPSCDKLFGPGNSYVTEAKQQVAQSGAAAIDMPAGPSEVLVIADAGAQPAFVAADLLSQAEHGPDSQVLLLSDSDGLIDAVQVQLEVQLAQLSRADIARQALAQSRMIKVQALDEAFAISNRYAPEHLILALREPRAWLAQVEAAGSVFLGDYTPEALGDYCSGTNHVLPTSGAARAYSGVSVASFQNMVSVQAASKAGIDGIGQCALILARAEGLDAHANAVALRMGVAA
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: YIDC_BEII9
Sequence: MKQDSRNLYLAIGLSLLVLIGWNYFFAGPQVEKARQAQIVREQQAQTQTTSDTTARSDLNVPGQRSLPGESPQTQLSRPEALAASPRVKLDTPNLFGSINLRGARIDDVSLKAYRETVAKDSPNIVLLSPSGTPAPYYADAGFVAPAEAGLLLPKSDTLWSADREVLTPEAPVTLTYDNGQGLIFHRTISVDDRFMFTLTDKVENKTDKPVTLYPYSLVSRHGRPVTAGYAVLHEGMVGVIGDNGLQEITYDKIHKEENATKSFKGTGGWLGFTDKYWAAVIAPDQATPFEGRFSERGTTTPLYQTDALGPALTIAPGGTGGDMSRLFAGAKETQTLDDYRNELGIKKFDLLIDWGYFYFITRPMFWILHTIYQVVGNFGVAILCITVLVKAVFFPLANRSYLSMAKMKAIQPQMLALRERYADDKVKQQQELMELYKREKINPVAGCLPMLIQIPVFFALYKVLFVTIEMRQAPFFGWIRDLSAPDPTNIFNLFGLLPFDPTHLPMIGHFLAIGIWPLIMGVSMFFQMKMNPEPADPVQKQMFSWMPVIFTFMLGTFPSGLVIYWTWNNTLSVLQQSLIMKRAGVKVELWDNLMSTFRKKAVT
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: COBS_PYRCJ
Sequence: MQCLRALLSFFTIIPAGVAKLDFKCAWALPYVVPPLVAGPAAAALWLGASPHVAYLLLLLMTGLNHLDGLADVADALMVRDRERARAVLEDPRRGTGGIFAVVATYAVATASTASPLQLLLAEVFSKALIVTVAAFSKPFKPGLGALFIDGARSTWPLALPALAVIICLRPAATLAALAVALALYAVAYQHLGGANGDVFGYLLEVSRVAYIVTWHM
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSBI_SINAL
Sequence: MLTLKLFVYTVVIFFVSLFIFGFLSNDPGRNPGREE
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.8 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: PSIE_PECAS
Sequence: MAGSARSAMAAKALQTILNIGLLALATILVIFLVKETFHLAKVLLISSEKDSSYQLIEGIVIYFLYFEFIALIVKYFQSGYHFPLRYFIYIGITAIIRLIIVDHKSPSDTLVYSAAILLLVVTLYLANSNRLKRE
What are the official names of this protein?
Protein PsiE homolog.
What is the protein family that this protein belongs to?
Belongs to the PsiE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSBF_PSINU
Sequence: MTLDRTYPIFTVRWLAIHGLAVPTVFFLGSISAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: PA2BC_CRODU
Sequence: MRALWIVAVLLVGVEGHLLQFNKMIKFETRKNAIPFYAFYGCYCGWGGRGRPKDATDRCCFVHDCCYGKLAKCNTKWDIYPYSLKSGYITCGKGTWCEEQICECDRVAAECLRRSLSTYKYGYMFYPDSRCRGPSETC
What is the function of this protein?
Monomer CBc: The basic subunit of crotoxin is a snake venom phospholipase A2 (PLA2) that exhibits weak neurotoxicity (10-fold less than the heterodimer) and very strong anticoagulant effects by binding to factor Xa (F10) and inhibiting the prothrombinase activity (IC(50) is 0. 7 nM) (PubMed:18062812).  In addition, it shows the same effects described for the heterodimer and binds the nucleotide-binding domain (NBD1) of CFTR chloride channels and increases the channel current (PubMed:27241308).  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Phospholipase A2 crotoxin basic subunit CBc, CB1, CTX subunit CBc, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TPMT_VIBCH
Sequence: MRDPEFWHNKWAANQIGFHLEDVNPLLIRFWSDLAPKRSEKVLVPLCGKSEDLIWLANQHDSVQGVELSQIAVRSFFAEHFYTPTVTRLNAQHELYQFDELTLFTGDFFTAPVESVDLVYDRAALVALPEEMRAEYAQRVLQLLKPGGRILLVSMDYVQTELSGPPFSVPEAEIRTLFMGCEVRRVYQDTSIDPHLNKRTQAGLSRFAEEVWVIEKSE
What are the official names of this protein?
Thiopurine S-methyltransferase, Thiopurine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAC1F_HUMAN
Sequence: MSESEGGKDTTPEPSPANGAGPGPEWGLCPGPPAVEGESSGASGLGTPKRRNQHSKHKTVAVASAQRSPRALFCLTLANPLRRSCISIVEWKPFDILILLTIFANCVALGVYIPFPEDDSNTANHNLEQVEYVFLVIFTVETVLKIVAYGLVLHPSAYIRNGWNLLDFIIVVVGLFSVLLEQGPGRPGDAPHTGGKPGGFDVKALRAFRVLRPLRLVSGVPSLHIVLNSIMKALVPLLHIALLVLFVIIIYAIIGLELFLGRMHKTCYFLGSDMEAEEDPSPCASSGSGRACTLNQTECRGRWPGPNGGITNFDNFFFAMLTVFQCVTMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKQREKQQMEEDLRGYLDWITQAEELDMEDPSADDNLGSMAEEGRAGHRPQLAELTNRRRGRLRWFSHSTRSTHSTSSHASLPASDTGSMTETQGDEDEEEGALASCTRCLNKIMKTRVCRRLRRANRVLRARCRRAVKSNACYWAVLLLVFLNTLTIASEHHGQPVWLTQIQEYANKVLLCLFTVEMLLKLYGLGPSAYVSSFFNRFDCFVVCGGILETTLVEVGAMQPLGISVLRCVRLLRIFKVTRHWASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDQTHTKRSTFDTFPQALLTVFQILTGEDWNVVMYDGIMAYGGPFFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLASGDAGTAKDKGGEKSNEKDLPQENEGLVPGVEKEEEEGARREGADMEEEEEEEEEEEEEEEEEGAGGVELLQEVVPKEKVVPIPEGSAFFCLSQTNPLRKGCHTLIHHHVFTNLILVFIILSSVSLAAEDPIRAHSFRNHILGYFDYAFTSIFTVEILLKMTVFGAFLHRGSFCRSWFNMLDLLVVSVSLISFGIHSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYTCTDEAKHTPQECKGSFLVYPDGDVSRPLVRERLWVNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDAYAEDHGPIYNYRVEISVFFIVYIIIIAFFMMNIFVGFVIITFRAQGEQEYQNCELDKNQRQCVEYALKAQPLRRYIPKNPHQYRVWATVNSAAFEYLMFLLILLNTVALAMQHYEQTAPFNYAMDILNMVFTGLFTIEMVLKIIAFKPKHYFTDAWNTFDALIVVGSIVDIAVTEVNNGGHLGESSEDSSRISITFFRLFRVMRLVKLLSKGEGIRTLLWTFIKSFQALPYVALLIAMIFFIYAVIGMQMFGKVALQDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLASLPGNRCDPESDFGPGEEFTCGSNFAIAYFISFFMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPGAKGRIKHLDVVALLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVTFNATLFALVRTSLKIKTEGNLEQANQELRIVIKKIWKRMKQKLLDEVIPPPDEEEVTVGKFYATFLIQDYFRKFRRRKEKGLLGNDAAPSTSSALQAGLRSLQDLGPEMRQALTCDTEEEEEEGQEGVEEEDEKDLETNKATMVSQPSARRGSGISVSLPVGDRLPDSLSFGPSDDDRGTPTSSQPSVPQAGSNTHRRGSGALIFTIPEEGNSQPKGTKGQNKQDEDEEVPDRLSYLDEQAGTPPCSVLLPPHRAQRYMDGHLVPRRRLLPPTPAGRKPSFTIQCLQRQGSCEDLPIPGTYHRGRNSGPNRAQGSWATPPQRGRLLYAPLLLVEEGAAGEGYLGRSSGPLRTFTCLHVPGTHSDPSHGKRGSADSLVEAVLISEGLGLFARDPRFVALAKQEIADACRLTLDEMDNAASDLLAQGTSSLYSDEESILSRFDEEDLGDEMACVHAL
What is the function of this protein?
Voltage-dependent L-type calcium channel activates at more hyperpolarized voltages and exhibits a robust calcium-dependent inactivation (CDI), due to incoming calcium ions, during depolarizations.
What are the official names of this protein?
Voltage-dependent L-type calcium channel subunit alpha-1F, Voltage-gated calcium channel subunit alpha Cav1.4.
What is the protein family that this protein belongs to?
Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. CACNA1F subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PSBK_ANTAG
Sequence: MFYIHLENTFDLSSTILVKLPEAYAIFDPIVDVMPIIPLFFFLLAFVWQASVSFR
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein K, PSII-K.
What is the protein family that this protein belongs to?
Belongs to the PsbK family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.