PharMolix/UniProtQA huggingface dataset:
Protein: TF2LX_MACFA
Sequence: MEAAADGPAETRSRVEKDSRRAKKDSPAKTQSPAQDTSIMLRNNADTGKVPALPEHKKKRKGYLPAESVKILRDWMYKHRFRAYPSEAEKRMLSKKTNLSLSQISNWFINARRRILPDMLQRRGNDPIVGHKTGKDAHATHLRSTDASVPAKSGPRGSDNVQSLPLRSSPKGQMSGEKIPEPGSAPSQKLTVIAQPKKKVKVSNITSLSSPERVSTEEYADFSSFQLLVDAAVQRAAELELEKKQESNP
What is the function of this protein?
May have a transcription role in testis.
What are the official names of this protein?
Homeobox protein TGIF2LX, TGF-beta-induced transcription factor 2-like protein, TGFB-induced factor 2-like protein, X-linked, TGIF-like on the X.
What is the protein family that this protein belongs to?
Belongs to the TALE/TGIF homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: 084R_FRG3G
Sequence: MLWEAVTDKPVKLKGLLELLLNNMDSARLVVTSQSVSVVDYQSNMAVTASMPSSVFTSYVYKSDAECLYAGLPHAALPDLKSFKAKCNVTLRLMGDPECGQYTMKIIIANASHMSTSINMVVDHGKKEADRGHPEGAGKPFTLTQQEFNTLCKTFKQGPVNLGVFGGVLVASGGVDGIKVKEVAFGAPDCVTPHVKLCVHAEKMSRLVKMGPFSAGSLTVCVAQGSVTVSTCGHLGSLTVTLFEG
What are the official names of this protein?
Uncharacterized protein 084R.
Protein: FPG_PSEPW
Sequence: MPELPEVETTRRGIAPHLEGQRVSRVVVRDRRLRWPIPEDLDVRLSGQRILSVERRAKYLLINAEVGTLISHLGMSGNLRLVQLGLPAAKHEHVDIELESGLMLRYTDPRRFGAMLWSLDPLNHELLLRLGPEPLTDLFDGERLFQLSRGRTMAVKPFIMDNAVVVGVGNIYATEALFAAGIDPRREAGGISRTRYLKLAIEIKRVLAAAIEQGGTTLRDFIGGDGQPGYFQQELFVYGRGGMPCKLCGTTLREAKLGQRASVYCPRCQR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: ATR_CITFR
Sequence: MYRIYTRTGDNGTTALFGGSRIDKDDIRVEAYGTVDELISQLGVCYASTRQAELRQELHAMQKMLFVLGAELASDQKGLTRLKQRIGEEDIQALEQLIDRNMAQSGPLKEFVIPGKNLASAQLHVARTLTRRLERILIAMGRTLTLRDEARRYINRLSDALFSMARIEETTPDVCA
What are the official names of this protein?
Corrinoid adenosyltransferase, Cob(II)alamin adenosyltransferase, Cob(II)yrinic acid a,c-diamide adenosyltransferase, Cobinamide/cobalamin adenosyltransferase, ORFW.
What is the protein family that this protein belongs to?
Belongs to the Cob(I)alamin adenosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHLC_CLOPF
Sequence: MKRKIYKLLICATIATSLWAVRTTKVYAWDGKADGTGTHAMIATQGVTILENDLSSNEPEVIRNNLEILKQNMHDLQLGSTYPDYDKNAYDLYQDHFWDPDTDNNFTKDSKWYLSYSIPDTAESQIRKFSALARYEWKRGNYKQATFYLGEAMHYFGDADTPYHAANVTAVDSPGHVKFETFAEDRKDQYKINTTGSKTNDAFYSNILTNEDFNSWSKEFARSFAKTAKDLYYSHANMSCSWDEWDYAAKVALANSQKGTSGYIYRFLHDVSDGKDSSANKNVNELVAYITTGGEKYAGTDDYMYFGIKTKDGQTQEWTMDNPGNDFMTGSQDTYTFKLKDKNLKIDDIQNMWIRKSKYTEFGDDYKPANIKVIANGNVVLNKDINEWISGNSTYNIK
What is the function of this protein?
Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture.  Constitutes an essential virulence factor in gas gangrene.  Binds to eukaryotic membranes where it hydrolyzes both phosphatidylcholine and sphingomyelin, causing cell rupture.  The diacylglycerol produced can activate both the arachidonic acid pathway, leading to modulation of the inflammatory response cascade and thrombosis, and protein kinase C, leading to activation of eukaryotic phospholipases and further membrane damage.
What are the official names of this protein?
Phospholipase C, PLC, Alpha-toxin, Hemolysin, Lecithinase, Phosphatidylcholine cholinephosphohydrolase.
What are the subcellular locations of this protein?
Secreted.
Protein: TNFB_CANLF
Sequence: MTPPGRLYLLRVRSAPVLLLLGLLLGLPPGAQGFPGVGISPSAARTAYQHPQKHFIQGTLKPAAHLIGDPSIQNSLRWRANTDRAFLRHGFSLSNNSLLVPTSGLYFVYSQVVFSGEGCFPKATPTPLYLAHEVQLFSSQYPFHVPLLSAQKSVCPGPQGPWVRSVYQGAVFLLTQGDQLSTHTDGISHLLLSPSSVFFGAFAL
What is the function of this protein?
Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (By similarity).  In its heterotrimeric form with LTB binds to TNFRSF3/LTBR.  Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo (By similarity).
What are the official names of this protein?
Lymphotoxin-alpha, LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1.
What is the protein family that this protein belongs to?
Belongs to the tumor necrosis factor family.
What are the subcellular locations of this protein?
Secreted. Membrane. Note=The homotrimer is secreted. The heterotrimer is membrane- associated.
Protein: ABCB6_MESAU
Sequence: MVTVGNYCEAEGPLGPAWAQNGLSPCFFFTLVPSTLMALGALALVLVLPCRRRDVPSGTEELFWAADSRVAPYALQLFLATLQVALPLAGLAGRVGTARGVRLPGYLLLASMLGSLASACGLWLLVAERRQARQSLAMGVWMKFRHSSGLLLLWTVAFAAENLALVSWNSPQWWWARADLGQQVQFGLWVLRYVISGGLFILGLWAPGLRPQSYTLRVHEADQDVERNQAQSTDRTSTWRDLGRKLRLLSSYLWPRGSPALQFIVLICLGLMGLDRALNVLVPIFYRDIVNLLTSKAPWSSLAWTVTTYVFLKFLQGGGTGSTGFVSNLRTFLWIRVQQFTSRGVELRLFSHLHELSLRWHLGRRTGEVLRVVDRGTSSVTGLLSYLVFNIIPTLADIIIGIIYFSMFFNAWFGLIVFLCMSLYLFLTIVVTEWRAKFRRAMNTQENITRARAVDSLLNFETVKYYNAEGYEVERYREAIIKYQGLEWKSSASLVVLNQTQNLVIGLGLLAGSLLCAYFVSEQKLQVGDFVLFGTYITQLYMPLNWFGTYYRMIQTNFIDMENMFDLLKEETEVKDVPGAGPLRFHKGQIEFENVHFSYADGRETLQDVSFTVMPGQTVALVGPSGAGKSTILRLLFRFYDISSGCIRIDGQDISQVTQISLRSHIGVVPQDTVLFNDTIANNIRYGRIAAGDSEVEAAAQAAGIHDAILSFPEGYETQVGERGLKLSGGEKQRVAIARTILKAPDIILLDEATSALDTSNERAIQASLAKVCTNRTTIVVAHRLSTVVSADQILVIKDGCIIERGRHEALLSQGGVYAEMWQLQQKGQETVSEDSKPQDIA
What is the function of this protein?
ATP-dependent transporter that catalyzes the transport of a broad-spectrum of porphyrins from the cytoplasm to the extracellular space through the plasma membrane or into the vesicle lumen.  May also function as an ATP-dependent importer of porphyrins from the cytoplasm into the mitochondria, in turn may participate in the de novo heme biosynthesis regulation and in the coordination of heme and iron homeostasis during phenylhydrazine stress.  May also play a key role in the early steps of melanogenesis producing PMEL amyloid fibrils.  In vitro, it confers to cells a resistance to toxic metal such as arsenic and cadmium and against chemotherapeutics agent such as 5-fluorouracil, SN-38 and vincristin (By similarity).  In addition may play a role in the transition metal homeostasis (By similarity).
What are the official names of this protein?
ATP-binding cassette sub-family B member 6, ABC-type heme transporter ABCB6, Mitochondrial ABC transporter 3, Mt-ABC transporter 3, P-glycoprotein-related protein, Ubiquitously-expressed mammalian ABC half transporter.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Mitochondrion outer membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Lysosome membrane. Late endosome membrane. Early endosome membrane. Secreted, extracellular exosome. Mitochondrion. Endosome, multivesicular body membrane. Melanosome membrane. Note=Present in the membrane of mature erythrocytes and in exosomes released from reticulocytes during the final steps of erythroid maturation. Traffics from endoplasmic reticulum to Golgi during its glycans's maturation, therefrom is first targeted to the plasma membrane, and is rapidly internalized through endocytosis to be distributed to the limiting membrane of multivesicular bodies and lysosomes. Localized on the limiting membrane of early melanosomes of pigment cells (By similarity). Targeted to the endolysosomal compartment (By similarity).
Protein: THII_SHEWM
Sequence: MKFIVKLFPEIMMKSKPVRMRFTKMLETNIRNVLKKVDETAKVKREWDKIMVLVPDDRQDLVEAFAERLACIPGIAHVLQVSESTFESVDDIYQQTLAVYKDELAGKTFCVRVKRVGNHDFRSIEVERYVGGGLNQFTEAAGVRLKNPDMTINLEIDKESLYLVSKRIEGLGGYPMATQEDVLSLISGGFDSGVSSYQFIKRGSRTHYCFFNLGGDQHEIGVKQVAYHLWQKYGESHKVKFISIPFDPVVTEILEKIDNGQMGVILKRMMMRAAAKVARKMGIQALVTGEAMGQVSSQTLTNLSIIDRCTDQLILRPLIAMDKQDIINLSRKIGTEDLSKSIPEYCGVISQRPTVKAVLSKIEAEELKFSEDLIDRVIEAAEVIDIREIATSMDTKITSTETVGDINSGEVIIDVRAPEEEEQSPLEVEGVEVKAIPFFRLATKFADLDKSKTYLLYCDRGVMSKLQALYLQEQGYDNVKVYRP
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_ACTP7
Sequence: MYAVFQSGGKQHRVSEGQVVRLEKLEIATGEKFEFDSVLMVVNGEDVKIGAPVVAGAKVVAEVVAQGRGDKVKIVKFRRRKHSRKQQGHRQWFTEVKITGIQA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: YCGN_ECOSM
Sequence: MAEHLMSDVPFWQSKTLDEMSDAEWESLCDGCGQCCLHKLMDEDTDEIYFTNVACRQLNIKTCQCRNYERRFEFEPDCIKLTRENLPTFEWLPMTCAYRLLAEGKDLPAWHPLLTGSKAAMHGERISVRHIAVKESEVIDWQDHILNKPDWAQ
What are the official names of this protein?
UPF0260 protein YcgN.
What is the protein family that this protein belongs to?
Belongs to the UPF0260 family.
Protein: SDHF2_RAT
Sequence: MAVVTLIPTLARVLSKHSLLSPLLSVTSFRRFYRGDSPTDSQKDMIEIPLPPWQERTDESIETKRARLLYESRKRGMLENCILLSLFAKEYLHNMTEKQLNLYDRLINEPSNDWDIYYWATEAKPAPEIFENEVMELLREFTKNKNKEQRLRAPDLEYLFEKPR
What is the function of this protein?
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer.
What are the official names of this protein?
Succinate dehydrogenase assembly factor 2, mitochondrial, SDH assembly factor 2, SDHAF2.
What is the protein family that this protein belongs to?
Belongs to the SDHAF2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: KTHY_BACVZ
Sequence: MSGLFITFEGPEGAGKTTVLQEMKEILSAEGLPVTATREPGGIDIAEQIREVILNKNNTLMDAKTEALLYAAARRQHLAEKVQPALKEGRIVLCDRFIDSSLAYQGYARGLGIDEVLSINQFAIGDTMPDVTIYFSIEPEEGLKRITSNDSREKNRLDLEALHFHTKVREGYQKVMQRFPERFHTIDASKKKELVIQDALQVINEALKKIQL
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: EIF3D_ANOGA
Sequence: MSDTISCTPETATFEAPQLQFNEDGWGPCELPDAFKDIPYQPFSKSDRLGKISDWTGTAQTDKKFSNKYASQFGGGSQYAYFHEEDETTFHLVDSARIQKPPHQRGRFRGNMRNNRSGRGRGARGGVQVGGMTTLSKSANKMRDQRRGTTRKWGMRGPPPKIRDASVTVRPDWVTIEEMDFPRLAKLSLPSVKEGEDIMTCGTLEYYDKTYDRVNVKNERPLQSVDRIFHTVTTTDDPIIRQLSKTHGNVYATDAILATIMCCTRSNYSWDIVIDKIGGKLFMDKRDNTEFDLLTVNETASEPPQEDGNSLNSPRNLAIEATFINHNFSQQVLKSGEKEPKYKFQQPNPFIGDDEDGEVASVAYRYRKWDLNNGITLVARCEHDAVLKMPQGDTQFLTIKALNEWDSKIANAVEWRQKLDTQRGAILANELRNNSCKLAKWTVQALLAGSDQLKFGYVSRAHVRDSSKHVILGTQQFKPQEFANQINLSMDNAWGILRCIIDICMKQKDGKYLIMKDPNKPMVRLYDIPDNTFDSDGEGEEGDDGEAFQPMYGYSAAASTSANVTAAQSNTSATVPDQSEKASA
What is the function of this protein?
mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.  In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit D, eIF3d, Eukaryotic translation initiation factor 3 subunit 7.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit D family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_AROAE
Sequence: MRHRSGLRKLNRTSSHRQAMFRNMANSLLRHEVIKTTLPKAKELRRVVEPLITLGKKPSLSNRRLAFNRMRDREMVVKLFDVLGPRFAERNGGYLRILKFGFRDGDNAPLALIELLDRPDEGEEGANVSEAAAA
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: KDPA_METB6
Sequence: MSVNDWAFLVLIGVILALLLIPTGEFMFRVYTGKKTFLSPLFVPVEAWILKACGAGSDEEMDWKSFAVAMMIFSVIGIVFVFILQEVQQFLPLNPLGATAVPWDLSLNTAVSFATNTNWQFYVPETTVSYLTQMIGLTVQNFMSAAVGMVVLVAFIYGFSRRSSHTIGNFWVLLLRSIWILLPLSFVIALVLVSQGAPQTLSGPVTVPLLNATNDSGGNIITTQLISLGPAASQIAVKMLGTNGGGFFNANSAHPFENPTWFTDLVEIVAILLIPVSLCFMFGKMIGSVKKGIAILIAMMILFVPLLGLGIWSEIGGNPAFTPLGISQAPSHLQSGGNMEGKEVRFGPVQSAAFSVITTVTSCGAVNSMHDSFMPLGGLVQIFDIQLGEIVFGGVGSGLYCMLVFVIIAMFIAGLMVGRTPELYGKKIEPYEMKLSTIHILIPIFLILIGTAIAVSITAGTSMTANPGPHGFSEILYAFSSVSQNNGSAFAGLSSDTFYNLTTAFCMFVGRYAIAIITLALAGAFVAKKIVPPGEGTLQDHRPLFIIWVVFTILIIGALSFLPALSLGPVVEFLIQMGRGVIHV
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: 3S11_HEMHA
Sequence: LECHNQQSSQPPTTKSCPGDTNCYNKRWRDHRGTIIERGCGCPTVKPGINLKCCTTDRCNN
What is the function of this protein?
Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.
What are the official names of this protein?
Short neurotoxin 1, Toxin II.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type I alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SYI_METBU
Sequence: MIKEVTDQYNAKEIETKVHEFWEANNAYRSVREHRKGAKKFYFVDGPPYTTGHIHLGTAWNKIIKDSILRYMSMNDHDILDRAGWDMHGLPIEVKVEGALGFESKKDIETYGVGNFIEKCKEFALRQKDDMTEQFQTLGVWLDWEDPYMTLKDEYIEAAWWTLKQAQDKNLLETGKRVVNWCPRCETAIADAEVEYEDREDPSTYIKFKLKDEDNTFVVIWTTTPWTIPSNIAVAVHPEFEYSKVKAISENSATEILIIASELVENVLRIGRYLDYEILSTMSGKDLEGTVYEHPLADLVPLQAEIEHRICNADYVTADSTGCVHIAPGHGVDDFEVGVKNEFPIFCPVGPNGSYTHEAGKYCGMNILDANRVVMDDLLERGLLMAERMISHRYGHCWRCKTAIIYLATEQWFLKIGELKEDMLEEIKKVNWTPEWAGSARFKDWIEGARDWCISRQRYWGIPIPVWKCSSCNSLTVVGTRKELIERSGADPHIELHRPYVDKVTIPCECGGTMKRVEDVFDVWFDSAVASWATLRFPHQKEKFNEWWPADFITEGHDQTRGWFYSQLGASMVAFGKAPYKNVLMHGFTLDGSGKKMSKSIGNVIQPAEVIDKFGADTLRSYVLSASAPWEDLKFNWDELATVHRTNNILWNVYRFPLPYMALDDFDPQKVSYESVEAYLRSEDKWILSRMQTVIAEVNKAMDARLLHKAMRSINEFVLEDLSRWYIQLIRPRTWVEADNPDKLAVYRVLYDVFVTTAKLIAPFMPHLAEEMYQNLVRNIDENAPVTIHLCDWPVVNEALVDTSLEAQMKVARSIVEASSNARQKVGRKLRWPVSRIVVSPTDENTIAAVEGLRSVLMDQTNAKDIETTKVGESWNELGVESTPNPGAIGPVFKGNAGNISAAIGAMDAYDLKKGLAGGEMEISLADGTNVTITEKMVNFSETVPEDVGSAEFNCGVVFVDAKLTHEIESEGYSREVIRRIQDMRKELDLDVDDSIRGHIQISDERVLDLVLDFENYIAKEVRANVLVIGLDVETTGELAKEWNVEGIPMTIAISKEE
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: USP_ORYSJ
Sequence: MASDGDGAAAVAALGISGGGGDDWAPPLRRNLPLLAPHEVKLAKLLLSEGQSHLFEHWPEPGVDDDKKRNFFDQVCRLNSSYPGGLASYIQNARKLLADSKAGKNPYDGFSPSVPSGEVLTFGDDNFVSLEEAGVKEARHAAFVLVAGGLGERLGYKGIKVALPRETTTGKCFLQHYIESILALQEASCKLVEGECNTKIPFVIMTSDDTNALTVKLLESNSYFGMEPSQVHILKQEKVACLADNDARLALDPNDKYKIQTKPHGHGDVHALLYSSGLLEQWKSTGRKWVLFFQDTNGLLFNAIPSALGVSATKGYNVNSLAVPRKAKEAIGGITKLTHVDGRTMVINVEYNQLDPLLRATGHPDGDANCETGYSPYPGNINQLILEIGPYMEELQKTHGAISEFVNPKYTDSTKTAFKSSTRLECMMQDYPKTLPPSAKVGFTVMDAWLTYAPVKNNPEDSAKVPKGNPYHSATSGEMAIYRANSLILRKAGAQIADPVIDTFNGQEVEVWPRITWIPRWGLIFKDVKAKVHSNSSVSQRSALVINGKNITIQGLSLDGTLIVNAKDEAKFNVTGHIENKGWTIQHVDHKDTSEKEEIRIRGFKFNKVEQLELNY
What is the function of this protein?
May function as the terminal enzyme of the myo-inositol oxidation (MIO) pathway.  May also play a role in the salvage pathway for synthesis of nucleotide sugars (By similarity).
What are the official names of this protein?
UDP-sugar pyrophosphorylase.
What is the protein family that this protein belongs to?
Belongs to the USP family.
Protein: REP_BPM13
Sequence: MIDMLVLRLPFIDSLVCSRLSGNDLIAFVDLSKIATLSGMNLSARTVEYHIDGDLTVSGLSHPFESLPTHYSGIAFKIYEGSKNFYPCVEIKASPAKVLQGHNVFGTTDLALCSEALLLNFANSLPCLYDLLDVNATTISRIDATFSARAPNENIAKQVIDHLRNVSNGQTKSTRSQNWESTVTWNETSRHRTLVAYLKHVELQHQIQQLSSKPSAKMTSYQKEQLKVLSNPDLLEFASGLVRFEARIKTRYLKSFGLPLNLFDAIRFASDYNSQGKDLIFDLWSFSFSELFKAFEGDSMNIYDDSAVLDAIQSKHFTITPSGKTSFAKASRYFGFYRRLVNEGYDSVALTMPRNSFWRYVSALVECGIPKSQLMNLSTCNNVVPLVRFINVDFSSQRPDWYNEPVLKIA
What is the function of this protein?
Isoform G10P protein binds to double-stranded DNA and prevents hydrolysis by nucleases.  Additionally, G10P is an inhibitor of DNA replication and may have a role in the transition from semiconservative replicative form DNA replication to single-stranded DNA synthesis in the life cycle.
What are the official names of this protein?
Replication-associated protein G2P, Rep, G2P, Gene 2 protein.
What is the protein family that this protein belongs to?
Belongs to the inovirus G2P protein family.
Protein: SYS_METMA
Sequence: MLELKFVRNNPDIVGRALISRNMGTELIDSLLEYDAAWRECLIEGDDLKHKRNVVTREIAQLKKENKDAASRINEMQGINSRIKELDDKIRDYKSKINEIMLSIPNIPSETTPVGKDENDNPVVRVVGEPREFTFTPKPHWEIGESLDILDFERAAKISGQGFAVYKGMGAKLERALINFMLDVHTRQGYLEVFPPVLINEKAMTGTGQLPKFKDDMYGCTDGFYLAPTAEVPVTNLFMDEYMENLPVFLTAYTACFRREAGKHGQDTRGIIRNHQFNKVELVKFVMPETSYEELEKLTLDAEEILKLLKLPYRVVSLCTGDLGFSAAKTYDLEVWVPTQEKYREISSCSNFDNFQARRANIRYRTPEGPQFVHTLNGSGLAVGRTVVAILENYQREDGSVEIPEVLRPYMGGAEEIRKVCH
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UMP1_YEAST
Sequence: MNIVPQDTFKSQVSTDQDKSVLSSAVPSLPDTLRQQEGGAVPLSTQLNDRHPLESTLKNWETTQRQRQMEQYRQIFGIAEPMKRTMEMEIVNRTDFNPLSTNGSIHRDILLNKECSIDWEDVYPGTGLQASTMVGDDVHSKIEKQLGI
What is the function of this protein?
Short-lived chaperone present in the precursor form of the 20S proteasome and absent in the mature complex.  Required for the correct assembly and enzymatic activation of the proteasome.  Also prevents premature processing of the PRE2 propeptide.
What are the official names of this protein?
Proteasome maturation factor UMP1.
What is the protein family that this protein belongs to?
Belongs to the POMP/UMP1 family.
Protein: RL28_STRT1
Sequence: MAKVCYFTGRKTVSGNNRSHAMNKTKRVVKPNLQKVTVLIDGKPKKVWASARALKSGKVERV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: ALIS3_ARATH
Sequence: MSSNTASSSAGAAGSGDSSAARKNSKRPKYSKFTQQELPACKPILTPGWVISTFLIVSVIFIPLGVISLFASQDVVEIVDRYDTECIPAPARTNKVAYIQGDGDKVCNRDLKVTKRMKQPIYVYYQLENFYQNHRRYVKSRSDSQLRSTKYENQISACKPEDDVGGQPIVPCGLIAWSLFNDTYALSRNNVSLAVNKKGIAWKSDKEHKFGNKVFPKNFQKGNITGGATLDPRIPLSEQEDLIVWMRTAALPTFRKLYGKIESDLEMGDTIHVKLNNNYNTYSFNGKKKLVLSTTSWLGGKNDFLGIAYLTVGGICFILALAFTIMYLVKPRRLGDPSYLSWNRNPGGR
What is the function of this protein?
Required for the lipid transport activity of the ALA/ALIS P4-ATPase complex.
What are the official names of this protein?
ALA-interacting subunit 3, AtALIS3.
What is the protein family that this protein belongs to?
Belongs to the CDC50/LEM3 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Prevacuolar compartment membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=In a heterologous system, the final intracellular localization after exit from the endoplasmic reticulum is the prevacuolar compartment in the presence of ALA2 and the Golgi in the presence of ALA3.
Protein: A622L_TOBAC
Sequence: MVVSEKSKILIIGGTGYIGKYLVETSAKSGHPTFVLIRESTLVNPEKSKLIDTFKSYGVTLLFGDISNQESLLKAIKQVDVVISTVGGQQFADQVNIIKAIKEAGNIKRFLPSEFGFDVDHAHAIEPAASLFALKVKIRRMIEAEGIPYTYVICNWFADFFLPNLGQLEAKTPPRDKVVIFGDGNPKAIYVKEEDIATYTMKAVDDPRTLNKTLHMRPPANILSFNEIVSLWEEKIGKTLEKLYLSEEDILHIVQEGPMPLRVNLAICHSVFVNGDSANFEIQPSTGVEATELYPKVKYTTVDEYYNKFV
What is the function of this protein?
Involved in the biosynthesis of pyridine alkaloid natural products, leading mainly to the production of anabasine, anatabine, nicotine and nornicotine, effective deterrents against herbivores with antiparasitic and pesticide properties (neurotoxins); nornicotine serves as the precursor in the synthesis of the carcinogen compound N'-nitrosonornicotine (NNN) (PubMed:19002761).  Reductase that may be involved in a late step of tobacco alkaloid biosynthesis (PubMed:19002761).  Maybe involved in either the formation of a nicotinic acid-derived precursor or the final condensation reaction of tobacco alkaloids (PubMed:19002761).
What are the official names of this protein?
Isoflavone reductase homolog A622-like, NtA622L.
What is the protein family that this protein belongs to?
Belongs to the NmrA-type oxidoreductase family. Isoflavone reductase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.