PharMolix/UniProtQA huggingface dataset:
Protein: AHPC_HELPJ
Sequence: MLVTKLAPDFKAPAVLGNNEVDEHFELSKNLGKNGVILFFWPKDFTFVCPTEIIAFDKRVKDFHEKGFNVIGVSIDSEQVHFAWKNTPVEKGGIGQVSFPMVADITKSISRDYDVLFEEAIALRGAFLIDKNMKVRHAVINDLPLGRNADEMLRMVDALLHFEEHGEVCPAGWRKGDKGMKATHQGVAEYLKENSIKL
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Alkyl hydroperoxide reductase C, 26 kDa antigen, Peroxiredoxin, Thioredoxin peroxidase.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METL4_MOUSE
Sequence: MSVVHHLPPGWLLDHLSFINKVNYQLCQHQESFCSKNNPTSSVYMDSLQLDPGSPFGAPAMCFAPDFTTVSGNDDEGSCEVITEKYVFRSELFNVTKPYIVPAVHKERQQSNKNENLVTDYKQEVSVSVGKKRKRCIAFNQGELDAMEYHTKIRELILDGSSKLIQEGLRSGFLYPLVEKQDGSSGCITLPLDACNLSELCEMAKHLPSLNEMELQTLQLMGDDVSVIELDLSSQIIENNSSFSKMITLMGQKYLLPPQSSFLLSDISCMQPLLNCGKTFDAIVIDPPWENKSVKRSNRYSSLSPQQIKRMPIPKLAAADCLIVTWVTNRQKHLCFVKEELYPSWSVEVVAEWYWVKITNSGEFVFPLDSPHKKPYECLVLGRVKEKTPLALRNPDVRIPPVPDQKLIVSVPCVLHSHKPPLTEVLRDYIKPGGQCLELFARNLQPGWMSWGNEVLKFQHMDYFIALESGC
What is the function of this protein?
N(6)-adenine-specific methyltransferase that can methylate both RNAs and DNA (PubMed:30982744).  Acts as a N(6)-adenine-specific RNA methyltransferase by catalyzing formation of N6,2'-O-dimethyladenosine (m6A(m)) on internal positions of U2 small nuclear RNA (snRNA): methylates the 6th position of adenine residues with a pre-deposited 2'-O-methylation (By similarity).  Internal m6A(m) methylation of snRNAs regulates RNA splicing (By similarity).  Also able to act as a N(6)-adenine-specific DNA methyltransferase by mediating methylation of DNA on the 6th position of adenine (N(6)-methyladenosine) (PubMed:30982744).  The existence of N(6)-methyladenosine (m6A) on DNA is however unclear in mammals, and additional evidences are required to confirm the role of the N(6)-adenine-specific DNA methyltransferase activity of METTL4 in vivo (By similarity).  Acts as a regulator of mitochondrial transcript levels and mitochondrial DNA (mtDNA) copy number by mediating mtDNA N(6)-methylation: m6A on mtDNA reduces transcription by repressing TFAM DNA-binding and bending (By similarity).  N(6)-methyladenosine deposition by METTL4 regulates Polycomb silencing by triggering ubiquitination and degradation of sensor proteins ASXL1 and MPND, leading to inactivation of the PR-DUB complex and subsequent preservation of Polycomb silencing (PubMed:30982744).
What are the official names of this protein?
N(6)-adenine-specific methyltransferase METTL4, Methyltransferase-like protein 4, N(6)-adenine-specific DNA methyltransferase METTL4, snRNA (2'-O-methyladenosine-N(6)-)-methyltransferase METTL4.
What is the protein family that this protein belongs to?
Belongs to the MT-A70-like family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GREA_BRUSU
Sequence: MEKFPMTPRGFEKLKEELRWRQQSERPRIIEAIAEARAHGDLSENAEYHAAKEAQSLNEGRINELEDLVARAEVIDVSKLTGDRIKFGATVTMIDEDTEEEKIYQIVGDQEADVKEGRISISSPIARALIGKGEGDTIEVNAPGGSRSYEIIALKFV
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: DEF21_ANTMA
Sequence: MGRGKIEVKRIENNTSRQVTFSKRRSGLMKKTHELSVLCDAQIGLIVFSTKGKLTEYCTPPFSMKQIIDRYVKAKGILPEMENRAGPHADNDQVIKELTRMKEETLNLQLNLQRYKGDDLSTVRFEELTELEKLLDQSLNKVRARKLELLHEQMENLKRTEFMLEKENQEMYHWLMSNQIQRQAEVEHHHQQQVMTELKLVEQQQPLMNEFPFFGEDLHLGTLPLLDTHSYRLQPTQPNLQDPAQIN
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
MADS-box protein defh21, DEFICIENS homolog 21.
What are the subcellular locations of this protein?
Nucleus.
Protein: IL8_CAVPO
Sequence: MPSQLRVAVLAAFLLSAVLCEGMVVTKLVSELRCQCIKIHTTPFHPKFIKELKVIESGPRCANSEIIVKLSDNRQLCLDPKKKWVQDVVSMFLKRTESQDS
What is the function of this protein?
Chemotactic factor that mediates inflammatory response by attracting neutrophils, basophils, and T-cells to clear pathogens and protect the host from infection.  Also plays an important role in neutrophil activation.  Released in response to an inflammatory stimulus, exerts its effect by binding to the G-protein-coupled receptors CXCR1 and CXCR2, primarily found in neutrophils, monocytes and endothelial cells.  G-protein heterotrimer (alpha, beta, gamma subunits) constitutively binds to CXCR1/CXCR2 receptor and activation by IL8 leads to beta and gamma subunits release from Galpha (GNAI2 in neutrophils) and activation of several downstream signaling pathways including PI3K and MAPK pathways.
What are the official names of this protein?
Interleukin-8, IL-8, C-X-C motif chemokine 8, Chemokine (C-X-C motif) ligand 8, Neutrophil attractant protein 1, NAP-1.
What is the protein family that this protein belongs to?
Belongs to the intercrine alpha (chemokine CxC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: BTS_ARATH
Sequence: MATPLPDFETARGGGAVASSSTTVLPSSVSSSSSSSRPLPVANSFSDDAEEISPILIFLFFHKAVCSELEALHRLALEFATGHHVDLRLLRERYRFLRSIYKHHCNAEDEVIFSALDIRVKNVAQTYSLEHKGESNLFDHLFELLNSATETDESYRRELARSTGALQTSVSQHLAKEQKQVFPLLIEKFKYEEQAYIVWRFLCSIPVNMLAVFLPWISSSISVDESKEMQTCLKKIVPGEKLLQQVIFTWLGGKSNTVASCRIEDSMFQCCLDSSSSMLPCKASREQCACEGSKIGKRKYPELTNFGSSDTLHPVDEIKLWHKSINKEMKEIADEARKIQLSGDFSDLSAFDERLQYIAEVCIFHSLAEDKIIFPAVDGEFSFSEEHDEEENQFNEFRCLIENIKSAGASSTSAAEFYTKLCSHADQIMETIQRHFHNEEIQVLPLARKNFSFKRQQELLYQSLCIMPLRLIERVLPWLTASLTEDEAKNFLKNLQAGAPKSDVALVTLFSGWACKGRKAGECLSPNGNGLCPVKTLSNIKEVNLQSCNACASVPCTSRSTKSCCQHQDKRPAKRTAVLSCEKKTTPHSTEVANGCKPSGNGRSCCVPDLGVNNNCLELGSLPAAKAMRSSSLNSAAPALNSSLFIWEMDSNSFGTGHAERPVATIFKFHKAISKDLEFLDVESGKLIDCDGTFIRQFIGRFHLLWGFYKAHSNAEDDILFPALESKETLHNVSHSYTLDHKQEEKLFGDIYSVLTELSILHEKLQSDSMMEDIAQTDTVRTDIDNGDCNKKYNELATKLQGMCKSIKITLDQHIFLEELELWPLFDKHFSIQEQDKIVGRIIGTTGAEVLQSMLPWVTSALSEDEQNRMMDTWKQATKNTMFDEWLNECWKGSPDSSSTETSKPSPQKDNDHQEILDQSGELFKPGWKDIFRMNQNELEAEIRKVYQDSTLDPRRKDYLVQNWRTSRWIAAQQKLPKEAETAVNGDVELGCSPSFRDPEKQIYGCEHYKRNCKLRAACCDQLFTCRFCHDKVSDHSMDRKLVTEMLCMRCLKVQPVGPICTTPSCDGFPMAKHYCSICKLFDDERAVYHCPFCNLCRVGEGLGIDFFHCMTCNCCLGMKLVNHKCLEKSLETNCPICCEFLFTSSEAVRALPCGHYMHSACFQAYTCSHYTCPICGKSLGDMAVYFGMLDALLAAEELPEEYKNRCQDILCNDCERKGTTRFHWLYHKCGSCGSYNTRVIKSETIPPDCSTSS
What is the function of this protein?
Essential protein (PubMed:20675571, PubMed:25452667).  Negatively regulates the response to iron deficiency and thus contributes to iron homeostasis (PubMed:20675571, PubMed:25794933).  Exhibits E3 ubiquitin-protein ligase activity in vitro (PubMed:24253678, PubMed:25452667).  Plays a role in root growth, rhizosphere acidification, and iron reductase activity in response to iron deprivation (PubMed:25452667, PubMed:27359166).  Facilitates 26S proteasome-mediated degradation of PYEL proteins in the absence of iron (PubMed:25452667).
What are the official names of this protein?
Zinc finger protein BRUTUS, Protein EMBRYO DEFECTIVE 2454.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Nucleus.
Protein: RS30_ARATH
Sequence: MGKVHGSLARAGKVRGQTPKVAKQDKKKKPRGRAHKRLQHNRRFVTAVVGFGKKRGPNSSEK
What are the official names of this protein?
40S ribosomal protein S30.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS30 family.
Protein: RSMA_XANC8
Sequence: MNSSFSAPAKKSLGQHFLADRYYIDRIVQAVDPRPGQHLVEIGPGQGAITFPLLRKHGALTVIEFDRDLIAPLTDAAAPIGQLQIIHRDVLAVDFTAVADGTPIRLVGNLPYNISSPILFHALDHAGAVADMHFMLQKEVVDRMAAGPGSKVYGRLSVMLQAYCEVTALFVVPPGAFRPPPKVDSAVVRLVPRDAASVLIKDRKRFADVVRAGFGQRRKTLRNALSTVCEPAHFEAAGVRPDARAEQLEVADFIRLANVELA
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1184_MICAN
Sequence: MDIQLINIGFGNIVSANRVIAIVSPESAPIKRIISDARDKGCLIDATYGRRTRAVIITDSSHVVLSAIQPETVAHRFVVNKEAPVNSSN
What are the official names of this protein?
Putative regulatory protein MAE_11840.
What is the protein family that this protein belongs to?
Belongs to the RemA family.
Protein: MDH_SHEPW
Sequence: MKVAVLGAAGGIGQALALLLKTQLPAGSKLSLYDIAPVTPGVAVDLSHIPTDVEVKGFAGEDPTAALEGADVVLISAGVARKPGMDRSDLFNINAGIVRNLVEKCAATSPKALIGIITNPVNTTVAIAAEVLKKAGVYDKNRLFGVTTLDVIRSETFVAAAKGLNVADVKVNVIGGHSGVTILPLLSQIEGVSFTDEEVAALTTRIQNAGTEVVEAKAGGGSATLSMGQAACRFGLSLVRGLQGEANVVECAYVDGGSEHAEFFAQPVVLGKNGVEQVLAYGDVSAFEANARDAMLDTLKADIDLGIEFVK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: RF1_PICTO
Sequence: MESEDYKRYEFKKALEELKDLHGRGTELISLYIPPDKQISDVVQYLREEYSTSSNIKSKSTRKNVLAAIESIMSRLKYYKQPPETGLVFFVGHIATRGDQTEMYTKIIEPPEPIQTFMYKCDSNFHLEQLESQLKEKDIYGLIVIDRKEATVGFLKGTRIEVVDYEQSLVPSKHHQGGQSSRRFERLIEIAANDFFKKIGEIANNAFMPLIKDINAVFIGGPGATKEYFLEKDYLRNEIKQKVKDLFDIGYTDESGLRELVEKASESIKDMKISREKDIINRFLREIKKPEGGLGVYGEDAIINALKSKNLDLLIISDTLKKRRYTYKCPVCNDTKTFTEKPRETPLCDKDNSEMELVDEDDLVEDLYKLADEAGTNVVFVSEDSDEGRLIKTAFGGLAGIMRYVPAIAP
What is the function of this protein?
Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
What are the official names of this protein?
Peptide chain release factor subunit 1, Translation termination factor aRF1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALGL_AZOVD
Sequence: MHKTRLALSCLLGSLLLSGAVHAAEALVPPKGYYAPVDIRKGEAPACPVVPEPFTGELVFRSKYEGSDAARSTLNEEAEKAFRTKTAPITQIERGVSRMVMRYMEKGRAGDLECTLAWLDAWAEDGALLTTEYNHTGKSMRKWALGSLAGAYLRLKFSSSQPLAAYPEQARRIESWFAKVGDQVIKDWSDLPLKRINNHSYWAAWAVMAAGVATNRRPLFDWAVEQFHIAAGQVDSNGFLPNELKRRQRALAYHNYSLPPLMMVAAFALANGVDLRGDNDGALGRLAGNVLAGVEKPEPFAERAGDEDQDMEDLETDAKFSWLEPYCALYSCSPALRERKAEMGPFKNFRLGGDVTRIFDPAEKSPRSTVGKRD
What is the function of this protein?
Catalyzes the depolymerization of alginate by cleaving the beta-1,4 glycosidic bond between two adjacent sugar residues via a beta-elimination mechanism.  May serve to degrade mislocalized alginate that is trapped in the periplasmic space.
What are the official names of this protein?
Alginate lyase, Poly(beta-D-mannuronate) lyase.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 5 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: VATA_CLOBA
Sequence: MKTGKIIKVSGPLVVAEGMDEANIYDVCKVGEKGLIGEIIEMRGDKASIQVYEETSGIGPGDPVVTTGEPLSVELGPGLIESMFDGIQRPLDAFMEAAKSSFLTRGVSVPSLNREKKWDFKPTAKVGDEVKSGDVIGTVQETPVVEQRIMIPIGIEGKIKEINAGSFTVTETIAIVETEKGDREVQLMQKWPVRKGRPYSAKINPVEPMLTGQRVIDTFFPVAKGGAAAIPGPFGAGKTVTQHQIAKWGDAEIVVYVGCGERGNEMTDVVNEFPELIDPKTGESLMKRTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYAVSIMADSTSRWAEALREMSGRLEEMPGDEGYPAYLGSRLADYYERAGKVECLGNDGRIGSITAIGAVSPPGGDISEPVSQSTLRIVKVFWGLDAQLAYQRHFPTINWLTSYSLYADTIDKWMNGNVAENWGALRLEAMTILQDEAQLQEIVRLVGIDALSEKDRLKLDVAKSIREDYLQQNGFHEIDTYTSLKKQYKMLSLILGYRKEAERALEAGVYLNDILAMEDLKDRIARSKYIHEDDLEKMDQIVVDLKNAIDNLINKGGVANA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type alpha chain is a catalytic subunit.
What are the official names of this protein?
V-type ATP synthase alpha chain, V-ATPase subunit A.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: OXYR_RAT
Sequence: MEGTPAANWSVELDLGSGVPPGEEGNRTAGPPQRNEALARVEVAVLCLILFLALSGNACVLLALRTTRHKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLGTWLGCLVASAPQVHIFSLREVADGVFDCWAVFIQPWGPKAYVTWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAAAAEGNDAAGGAGRAALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWDVNAPKEASAFIIAMLLASLNSCCNPWIYMLFTGHLFHELVQRFFCCSARYLKGSRPGETSVSKKSNSSTFVLSRRSSSQRSCSQPSSA
What is the function of this protein?
Receptor for oxytocin.  The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.
What are the official names of this protein?
Oxytocin receptor, OT-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GREA_STRPN
Sequence: MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDLSENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDEEEVYIIVGSAGADAFVGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: THEGL_MOUSE
Sequence: MEEGDFSGSSVRSEVTDGRNTTTTTETRTTSELQPKPLVLRLLEVQNGDEAEAVGEEGQEEDYEGSKTHKSHEVSASFRSHNSSDPPQSRKASDSLRSRKGIEPLEPRKTSDSFRSLMGSDPLQSSERQEDGKDDLFPNAVIMTSPSLIARYLPRLQLASLRAHPVTRDLVKKCFYSRKRVQDLSKPKKQWGTPDRRLFWGNQDPIRPVSEAALKAKLSKRIEDLAQPRLVSRHYVPNRIQYYYSCGRESVIWEISPPALVTRPSKRIQKLAKPNKFKAQSLIKRETVPGTTRYSDPSPRILRLSIAKGTNPSYLPPKTLETKISFSTLSAVATPRIVDLAHPRIKIEGLCYERERSELPIRPVAPAALLANPSKRTIFLAKSKRVHEDYLPIRDARWPVSYAATHSQVSERVQELANPHTRGPANLVYYDPNVFKVKPSALKAHCSDRVKELAEPIVR
What are the official names of this protein?
Testicular haploid expressed gene protein-like.
Protein: Y803_CHLPN
Sequence: MAAKTKTLELEDNVFLLLEGNLKRIFATPIGYTTFREFQNVVFNCANGQQEIANFFFEMLINGKLTQELAPQQKQAAHSLIAEFMMPIRVAKDIHERGEFINFITSDMLTQQERCIFLNRLARVDGQEFLLMTDVQNTCHLIRHLLARLLEAQKNPVGEKNLQEIQEEITSLKNHFDELTKALQ
What are the official names of this protein?
Protein CPn_0803/CP_1068/CPj0803/CpB0832.
What is the protein family that this protein belongs to?
Belongs to the chlamydial CPn_0803/CT_584/TC_0873 family.
Protein: Y475_MYCLE
Sequence: MSGHSKWATTKHKKAVIDARRGKMFARLIKNIEVAARVGGGDPVGNPTLYDAIQKAKKSSVPNGNIERARKRGAGEEVGGADWQVITYEGYAPNGVAVLIECLTDNRNRAAGEVRVAMTRNGGAMADPGSVAYLFSRKGVVTLEKNGLTEDDVLAAVLDAGAEEVNDLGDSFEVIAEPGDLVAVRTALQDAGIDYESAEASFQPSVSMPVDLDGARKVFKLVDALEDSDDVHNVWTNADVSDEVLAALDGE
What are the official names of this protein?
Probable transcriptional regulatory protein ML0475.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: A1BG_MOUSE
Sequence: MSLLATVLLLWGFTLGPGNTLMLDSGSEPKLWAEPQSLLEPWANLTLVCAVDLPTKVFELIQNGWFLSQVRLETQVLSYRFSLGAITSNNSGIYRCRCGVEPPVDIHLPALNKWTMLSNAVEVTGKEPLPRPLAHADPVDWITPGGLPVYVMCQVAMRGVTYLLRQEGVDGVQKPDVQHKGTAGFLIYKPGNYSCSYLTHAAGEPSEPSDIVTIKMYASQAPPTLCLMGNYLMIYPQKTYETLACKAPRNAAEFQLRQGGKVLKIHGFSPTRDAILYYVNLKELDNPGPFTCRYRMHKYMHVWSEDSKPVELMWSDETLQAPVLTAEPSSRDLEPGSTVQLRCTAPVSGLRFGLQRQGKPELVVVQMLNSSGTEAVFELHNISTIDSGNYSCIYMEQAPPFSGSSSSEPVELRVNGPPPKPRLEALWKSTVHLGQEAIFRCHGHVPRVSMELVREGFKTPFAVASTRSTSAYLKLLFVGPQHAGNYSCRYTALPPFTFESGISDPVEVIVEG
What are the official names of this protein?
Alpha-1B-glycoprotein, Alpha-1-B glycoprotein.
What are the subcellular locations of this protein?
Secreted.
Protein: AZR1_YEAST
Sequence: MKGEPKTYSMSDLSYYGEKAQQQNEKQQKQYVVRRNSTQSTSKQNVSVVLEDNASESNELPKGFILYASLIALALSLFLAALDIMIVSTIIEEVAKQFGSYSEIGWLFTGYSLPNALLALIWGRIATPIGFKETMLFAIVIFEIGSLISALANSMSMLIGGRVIAGVGGCGIQSLSFVIGSTLVEESQRGILIAVLSCSFAIASVVGPFLGGVFTSSVTWRWCFYVNLPIGGLAFFLFLFFYNPGLSTFQETMDNIRKFPSQFIEIVRNVAYHLLKIKGFSKLNGWRKPFMELIFMYDIIEFVFCSAGFTCILLAFTFGGNRYAWNSASIIILFIIGIVLVVLAGIYDFLVFPKFNIVKATPHYQPLMSWTNIKKPGIFTVNIALFLTCAGYISQFTYIVQYFQLIYNDSAWRAAVHLVACIISTVVTAILCGAITDKTRQIKPIIVISSIFGVVGAGILTLLNNNANNSAHIGLLILPGVAFGGLAQSSMLASQIQLDKKSPTFRSDFVSITTFNTFCKNLGQALGGVISNTVFSAAAIKKLTKANIQLPDGTTVDNLVIYRQTNFDGSHSKLGNIISESLTDVFYMALGFYALSLIFAVFASNKKVTASLR
What is the function of this protein?
Transporter protein required for adaptation to high stress imposed by low-chain organic acids, in particular by acetic acid, and for resistance to azoles, especially to ketoconazole and fluconazole.
What are the official names of this protein?
Azole resistance protein 1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MKCC_DICDI
Sequence: MDVEFTPSDTNKFEANITKQHQVIELNNQEEQQQPEQQEQPEQQEELKDNNEKIKTSEDSTTTTTTTATITTTGENSISITVTEANNNTNQLNKSTSSSSSLNNNKNEDNKSVTASIAPSSPVIESSAIESAIDSPYISSASVFSNATNNNNNTTTTNVVVPPPQLLESSTENITSAAEITPVTTTTTEETINIPKESIEVQKQLAETTTTAAITTTNSTQVTSTTVTNPDKLKCKMHRSNFIMTQIGGKKFTEMTLEQLLDEDDPQTGMGFKNPGPQGFLEYVGDTAPPPTPPPISTSNTTGKNTGKNSTTGKSEGKKATSNSSNVPPSPVLASSASPSPKLKSSSSSIRNSGAISGTSENGGGGNGSGTISKNTAPTTGNSTTTTTTTTSTTTSSSKDRKSVVQKQSTLGRLQKNEEERRKRKEQKRSRAREKPILIAGIEDLPAECLKMVKKSKIPEDKLIQHLNILLPILRFRTGYNLRHVPIVSSNNSTNSLGSSINKNNSNNTTTTTTTTNTNNKSPEVSTNSLDVNIINQNQNQTNSVQNNQINTSSNVITTNVIPTTTASQSSQAPYHPSHNGNEEDDYDDGSRLENAILPKGTVDLIETDRDVKKLYKNLKQIGSGGFGSVFLAKSTVDKCEIAIKKIAHVSAKAQRTNLNEIGFLNFCKHPNIVSYLRSHLVDDTIWIAMEYMQGGTLTEASQGHTFNESCIAYVAKGMLEGLMYLHAHNIVHRDIKSGNIMMTIDGKIKIVDFGLCVDANERKLVHMAGSPFWMSPEMIRGESYGCPTDIWSFAICLLELANGEPPHRKSSLTAMFTTATEGCAGLDKPERWTEHFTHFLNLCLEMDPSKRSTAEQLLKHPWINLSENPETMKKILAQIFIANVMNHLDN
What are the official names of this protein?
Probable serine/threonine-protein kinase mkcC, MAP kinase cascade C.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
Protein: LPXB_FRATM
Sequence: MRIGIVAGELSGDQLGGTLVEALKQKYPNAIIEGIGGPKMAAAGFKSLYPMDALSLIGFLEIISKGLRILSIRRKIINYFKQNKPDIFIGIDAPDFNLTVEKELRSAGIKTIHYVSPKIWVWREYRIKKIRKATDKILAILPFETEYYKNRHKFEAIYVGHPLAKNIPIHIDRAKYRDKLGLKGSSLPILSVLPGSRTTEVSRLLPLFLLALQKLVDAGYKFKAIMPLAKPSLKPLFAKYKEQIDSLGIEVFETNSHDVLKASDLSLLASGTATLEAMLCKLPMVVGYKLSWLSALIGRMLIGNHSYWAFPNILHKNEIIKELIQEDCTVDNLFSELKRLFDDKRRNDYIVEEFEKIHKEMVIDTESKIIQVLDTMIEKS
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: STX1B_MOUSE
Sequence: MKDRTQELRSAKDSDDEEEVVHVDRDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSAILAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDMLESGKLAIFTDDIKMDSQMTKQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRKKIMIIICCVVLGVVLASSIGGTLGL
What is the function of this protein?
Potentially involved in docking of synaptic vesicles at presynaptic active zones (By similarity).  May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm.
What are the official names of this protein?
Syntaxin-1B.
What is the protein family that this protein belongs to?
Belongs to the syntaxin family.
What are the subcellular locations of this protein?
Membrane; Single-pass type IV membrane protein.
Protein: MTNA_YERPP
Sequence: MQTLNTLDLQTTSLKIVNGQLWILDQQALPQRQEWLLADTVASLIEHIQALRVRGAPLIGLSASLLLALLAERGLSQALLEQALIALRESRPTAVNLMNNLARMQQALLQPNWVTAMAAEALRLVDEDRELCERIAQHGAALVKPGSNLLTHCNTGGLATAGIGTAIGVLLRAHQQGNLRQVWVDETRPLLQGGRLTAWELGELGIPYQLICDSMAASLMAQGQVDAIWVGADRIAANGDVANKIGTYSLAVLAHYHRIPFYVAAPHTTHDPDCPDGAAIPIEQRAASEVTGVSGGFGHCQWAPEDAAVYNPAFDVTPAALISGWVLDSGVITPEQVAAGFFQPHR
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: RL34_HYPNA
Sequence: MKRTFQPSNLRRARTHGFRERMSTKNGRKVLARRRAKGRKTLTA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: CBIT_SULIL
Sequence: MEWKYVIPGIPDNFFERDEEIPMTKEEIRALALSKLRIRKGDMILDIGCGTGSVTVEASLLVGSTGKVYGVDKEEKAINLTRRNAEKFGVLNNIVLIKGEAPEILFTINEKFDRIFIGGGSEKIKEIISASWEIIKKGGRVVIDAILLETVNNAISAMENIGFMNLEITEVIIAKGMKTKVGTAMMTRNPIFIISGEKQ
What is the function of this protein?
Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7.
What are the official names of this protein?
Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating).
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Archaeal-type CbiT family.