PharMolix/UniProtQA huggingface dataset:
Protein: NTAQ1_DROSI
Sequence: MTTDFLFPKIADCSYVSCYCEENVWKLCEQVKRTRPEELSKCYAVFVSNEGRTVPLWRQKAGRGDDQVVIWDYHVFFIHNPLLNRCLVFDLDTTLPFPTYFHKYVTETFRSDLALRPEHHRFFRVIPADTYLIEFSSDRRHMRRPDGSWIKPPPSYPPILSNSNMHCLGDFICMSAGKGPGAVYSLSEFVQNFYKSPHVMAQNNK
What is the function of this protein?
Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation.  Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule.  Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position.
What are the official names of this protein?
Protein N-terminal glutamine amidohydrolase, Protein NH2-terminal glutamine deamidase, N-terminal Gln amidase, Nt(Q)-amidase, Protein tungus.
What is the protein family that this protein belongs to?
Belongs to the NTAQ1 family.
Protein: CAPZA_CANGA
Sequence: MSNDFDTIIKNIIKDSPAGELEEVYQDLITIAGENSKETIIDAIAEYNVENSIPIDVDGKDVIISKYNKQGTKFVDPVNGIQFSVDHLHQKGLDVEEYSADIDADQKKAITDLGNYLSTNFPGRATFAVLPLEEQSKTAIIIVSTKYNPSNFWNGHWKSEYVYDKTEGKLSGTIDIDVHYYEDGNVKFHSSKLVEETNIKDPVASIKELEHKFEQDLQESFTDLNEKQFKSLRRRLPITRARVNWGKAIGNYRLGRDAAQGK
What is the function of this protein?
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends.  Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity).
What are the official names of this protein?
F-actin-capping protein subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the F-actin-capping protein alpha subunit family.
Protein: RS27_ENTH1
Sequence: MPLIEVDLLNPTAASEAKAHKMKRLVPTPNSYFLEIKCPKCGATTTTFSHAHRQILCQKCGQPLGQPTGGKLKLTQQCKFRIKK
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  Required for proper rRNA processing and maturation of 18S rRNAs.
What are the official names of this protein?
40S ribosomal protein S27, EHZC3 protein.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS27 family.
Protein: MLTF_ECOLC
Sequence: MKKLKINYLFIGILALLLAVALWPSIPWFGKADNRIAAIQARGELRVSTIHTPLTYNEINGKPFGLDYELAKQFADYLGVKLKVTVRQNISQLFDDLDNGNADLLAAGLVYNSERVKNYQPGPTYYSVSQQLVYKVGQYRPRTLGNLTAEQLTVAPGHVVVNDLQTLKETKFPELSWKVDDKKGSAELMEDVIEGKLDYTIADSVAISLFQRVHPELAVALDITDEQPVTWFSPLDGDNTLSAALLDFFNEMNEDGTLARIEEKYLGHGDDFDYVDTRTFLRAVDAVLPQLKPLFEKYAEEIDWRLLAAIAYQESHWDAQATSPTGVRGMMMLTKNTAQSLGITDRTDAEQSISGGVRYLQDMMSKVPESVPENERIWFALAAYNMGYAHMLDARALTAKTKGNPDSWADVKQRLPLLSQKPYYSKLTYGYARGHEAYAYVENIRKYQISLVGYLQEKEKQATEAAMQLAQDYPAVSPTELGKEKFPFLSFLSQSSSNYLTHSPSLLFSRKGSEEKQN
What is the function of this protein?
Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product.  Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus.  Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase F, Murein lyase F.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane.
Protein: TAUR_RHOCB
Sequence: MAIPVESFFLAPGGQGSLQHRLRQMVTEGILSGRFRPGDRMPSTRALAAHLGVARITVTLAYADLVASDYLLARGRSGTFVSAAAPDARKARPLPRDGARTDWARLLHPRAQGLPRPDRPRDWSLYRYPFIYGQADPELFDHQNWRACALQALGRREFHRLSADCYDEDDPLLVEYILRHILPRRGIAAVPSEVLITMGAQNGLWLAAQVLLGPGERAAMENPGYPGTRAVLGTTGAEVLSVDVDDRGLVPAQLPARLKLVVTTASHHCPTNATLPVERRLALLAAAEAGDFLILEDDYEFEMSFLQSAAPSLKSLDAGGRVVHVGSFSKSLFPGLRLGYLVAPAPFVAAVRALRATVLRHPPGQLQRTLALFLSLGHYDALVARMKAAYRLRREVMTKAIEDNGLQIAGQGGFGGSSFWMQAPGAVDTEDLALRLRAEGVLIEPGRVFFDPARERRNFYRLAYSSIGPAAIPEGIARIARALR
What is the function of this protein?
Transcriptional activator, which is essential for taurine-dependent expression of the tpa-tauR-xsc operon.  Acts by binding to direct repeats in the promoter region.
What are the official names of this protein?
HTH-type transcriptional regulator TauR.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
Protein: RL11_ICTPU
Sequence: MADQGEKKENPMRELRIRKLCLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEILEKGLKVREYELRKNNFSDSGNFGFGIQEHIDLGIKYDPSIGIYGLDFYVVLGRPGFSIADKKRKRGRIGFKHRIRKREAMRWFQQKYDGVILPGK
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: RS4A_ALKOO
Sequence: MARYTEAVCRLCRREGMKLYLKGDRCYTDKCAISKRTYAPGQHGQSRKKLSNYGLQLREKQKAKRFYGVLESQFRKYFEIADKQAGITGENLLRLLETRLDNVAYRLGFGSSRAEARQLVVHGHFTVNGKKVDIPSYLVSAGDTIAVAEKSKSSAKFKALAENAKGNTPNWLTVDVEKLEGKVVALPSREDIDLEIAENLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4 A.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: DNAA_BURCJ
Sequence: MNDFWQHCSALLERELTPQQYVTWIKPLAPVAFDASANTLSIAAPNRFKLDWVKSQFSGRIADLAREFWNTPIEVQFVLDPKAGMRSAPAGAAPAAPRAPLAPNGPAATVAAIAANLTANASAAPAAPADVPMTPSAAAARHLNADDADIDLPSLPAHEAAAGRRTWRPGPGAAPANGGEADSMYERSKLNPVLTFDNFVTGKANQLARAAAIQVADNPGISYNPLFLYGGVGLGKTHLIHAIGNQLLLDKAGARIRYIHAEQYVSDVVKAYQRKAFDDFKRYYHSLDLLLIDDIQFFSGKSRTQEEFFYAFEALVANKAQVIITSDTYPKEISGIDDRLISRFDSGLTVAIEPPELEMRVAILMRKAQSEGVNLSEDVAFFVAKHLRSNVRELEGALRKILAYSKFHGREISIELTKEALKDLLTVQNRQISVENIQKTVADFYNIKVADMYSKKRPANIARPRQIAMYLAKELTQKSLPEIGELFGGRDHTTVLHAVRKIADERSKDAQLNHELHVLEQTLKG
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPD_RICTY
Sequence: MSDIIKEIEEAWQIKENILNDSLKLIKLKSILNESIKSLNQGIIRVCEKQGNQWKVNEWVKKAILLYFITTESQLYNNNYNSWYDKVAPKFPADTDKNIFKEAAIRKVPGAIVRTGTYIAKNVVIMPSFINIGAYIDEGTMIDTWATIGSCAQIGKNCHISGGSGIGGVLEPLQAKPVIIEDNCFVGARSEIAEGIIVEEGSVISMGVFIGSSTKIVYRDTGKIIYGRIPAYSVVVPGVLPSPEAGKPGLYCVVIVKQVDKTTRAKVSINDLLR
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBN_ECO45
Sequence: MELIFLGTSAGVPTRTRNVTAILLNLQHPTQSGLWLFDCGEGTQHQLLHTAFNPGKLDKIFISHLHGDHLFGLPGLLCSRSMSGIIQPLTIYGPHGIREFVETALRISGSWTDYPLEIVEIGAGEIFDDGLRKVTAYPMEHPLECYGYRIEEHDKPGALNAQALKAAGVPPGPLFQELKAGKTIMLDDGRQINGADYLAVPVPGKALAIFGDTGPCDAALELAKGVDVMVHEATLDMAMEAKANSRGHSSTRQAAALAREAGVGKLIITHVSSRYDDKGCQHLLRECRSIFPATELANDFAVFSI
What is the function of this protein?
Zinc phosphodiesterase, which has both exoribonuclease and endoribonuclease activities.
What are the official names of this protein?
Ribonuclease BN, RNase BN, Ribonuclease Z homolog, RNase Z homolog.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family. RNase BN subfamily.
Protein: YCGR_ECOLI
Sequence: MSHYHEQFLKQNPLAVLGVLRDLHKAAIPLRLSWNGGQLISKLLAITPDKLVLDFGSQAEDNIAVLKAQHITITAETQGAKVEFTVEQLQQSEYLQLPAFITVPPPTLWFVQRRRYFRISAPLHPPYFCQTKLADNSTLRFRLYDLSLGGMGALLETAKPAELQEGMRFAQIEVNMGQWGVFHFDAQLISISERKVIDGKNETITTPRLSFRFLNVSPTVERQLQRIIFSLEREAREKADKVRD
What is the function of this protein?
Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner.  When bound to c-di-GMP it binds to elements of the flagellar motor (MotA (PubMed:20303158) and/or FliG and FliM (PubMed:20346719), binding to FliM also occurs in the absence of c-di-GMP), causing the motor to slow down.  Thus, increasing levels of c-di-GMP lead to decreased motility.  Probably binds 1 c-di-GMP dimer per subunit.
What are the official names of this protein?
Flagellar brake protein YcgR, Cyclic di-GMP binding protein YcgR.
What is the protein family that this protein belongs to?
Belongs to the YcgR family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: RLMKL_CITK8
Sequence: MNSLFASTARGLEELLKTELENLGAADCQVVQGGVHFQGDTRLVYQSLMWSRLASRIMLPMGECKVYSDLDLYLGVQAINWTEIFNPDATFAVHFSGLNDTIRNSQYGAMKVKDAIVDAFTRKNLPRPNVDRESPDIRVNVWLNKDTASIALDLSGDGLHLRGYRDRTGLAPIKETLAAAIVMRSGWQPGTPLLDPMCGSGTLLIEAAMWATDRAPGLHRGHWGFSGWAQHDEAIWQEVKAEAQTRARKGLAEYSSHFYGSDSDARVIERARSNARRAGIGELITFEVKDVAQLSNPLPKGPYGTVISNPPYGERLDSEPALIALHSLLGRTMKNQFGGWSLSLFSASPDLLNCLQLRADKQFKAKNGPLDCVQKNYHLAEKTPDSKPATVAEDYANRLRKNIKKLEKWARQEGIECYRLYDADLPEYNVAVDRYGEWVVIQEYAPPKTVDAQKARQRLFDIIAATLLVLEIAPNKLVLKTRERQKGKSQYQKMNEKGEFIEVSEYNARLWVNLTDYLDTGLFLDHRIARRMLGQMSKGKDFLNLFSYTGSASVHAGLGGARSTTTVDMSRTYLEWAERNLRLNGLSGRAHRLIQADCLGWLREANEQFDLIFIDPPTFSNSKRMDESFDVQRDHLVLMKDLKRLLRKGGTIMFSNNKRGFRMDLDGLAALGLKAQEITQKTLSQDFARNRQIHNCWLITAA
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNFA_SHEB2
Sequence: MNEYLLLLISTVLVNNFVLVKFLGLCPFMGVSSKLESAIGMSMATTFVLTLASILSYLVNQYLLLPFDLSYLRTMSFILVIAVVVQFTEMVVQKTSAALHRALGIYLPLITTNCAVLGVALLNVNEKHDFIQSAIFGFGAALGFSLVLILFSAMRERLAAADVPLPFKGGAIAMITAGLMSLAFMGFTGLVK
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit A, Rnf electron transport complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PAND_TRIEI
Sequence: MTTIKLMHAKLHRVRVTDAKPDYVGSVTIDSDLLEKVGILPLEEVQIVNLNNGQRWLTYVLPGQAGSGMVCPNGGAALLCKKDDILIIWANEQCDRAEVLENGHKAKIFVADENNHCREFLYQILNPNQGSVEFHSLPVIPEGKTSEYLQQMIETNKI
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGT_NEIMA
Sequence: MLKFTLHKKDGYARRGTLELNHGKIETPVFMPVGTYGSVKAMNPQNLHDIKAQIILGNTYHLWLRPGLEVVEQFGGLHGFIGWDKPILTDSGGFQVFSLSDMRKLTEEGCTFKSPINGDKLFLSPEISMKIQTVLNSDIAMQLDECTPGEATREQARKSLQMSLRWAERSKKAFEDLKNPNALFGIVQGAMYEDLREESLKGLEELDFPGLAIGGLSVGEPKPEMYRMLRAVGPILPEHKPHYLMGVGTPEDLVYGVAHGVDMFDCVMPTRNARNGWLFTRFGDLKIKNAKHKLDKRPIDESCTCYACQNFSRAYLHHLHRAGEILGAQLNTIHNLHFYQVIMAEMREAVEQGKFADWQAQFHENRARGTD
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: NUOCD_ECOLC
Sequence: MVNNMTDLTAQEPAWQTRDHLDDPVIGELRNRFGPDAFTVQATRTGVPVVWIKREQLLEVGDFLKKLPKPYVMLFDLHGMDERLRTHREGLPAADFSVFYHLISIDRNRDIMLKVALAENDLHVPTFTKLFPNANWYERETWDLFGITFDGHPNLRRIMMPQTWKGHPLRKDYPARATEFSPFELTKAKQDLEMEALTFKPEEWGMKRGTENEDFMFLNLGPNHPSAHGAFRIVLQLDGEEIVDCVPDIGYHHRGAEKMGERQSWHSYIPYTDRIEYLGGCVNEMPYVLAVEKLAGITVPDRVNVIRVMLSELFRINSHLLYISTFIQDVGAMTPVFFAFTDRQKIYDLVEAITGFRMHPAWFRIGGVAHDLPRGWDRLLREFLDWMPKRLASYEKAALQNTILKGRSQGVAAYGAKEALEWGTTGAGLRATGIDFDVRKARPYSGYENFDFEIPVGGGVSDCYTRVMLKVEELRQSLRILEQCLNNMPEGPFKADHPLTTPPPKERTLQHIETLITHFLQVSWGPVMPANESFQMIEATKGINSYYLTSDGSTMSYRTRIRTPSYAHLQQIPAAIRGSLVSDLIVYLGSIDFVMSDVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ATPF_RICPR
Sequence: MNFLDESFWLTISFVIFVYLIYRPAKKAILNALDTKISEIQEKVLKAKKLKEDAALLFEQTKLQIQKLETLRSQMIEESDKATKQIIQDKTKEMEEFLERKKADAIQLIQNQKSTASKDLQDEFCDEVITLVSKYFRSAKLSEKSIAKNLMDKSDFVHNDSKATYLH
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: VPS51_DICDI
Sequence: MSQSISDIKLVKFYYRHYKLGPQDFCREYGGNVDGLNKFLTGNYDSLAARDALRSFWERFNTNQLMKSQAGDEDDGDEFNSTFGGGDSMLLSPIKVTSPMSSSSSSTNTTNSNGQIIGNRSFSSLAEATSNATTTTTSTTTTGGKPESKRVRNLLKTYYGPGIGEGSDSSSMNDPLNIDGPSFNLNSYFDSIVKSSTLNQLIQKDNQMVSEIRTLDGDMKTLVYDNYTKFINATDIIKKMKTNVENMEEGMALLSKNMDLITNCSEKINSTLSVRRDRIDQLSGLQKFFQKLQFLTALPSSLNHCLAMQAYNQAVRYYNSNSGILKQYSHIPSFQNIQNECDSIMKTMKDKLYERLSSLSTSQTDCVESAEVLMDLLEPVELVRSKYLESRKHHTITLLENLEKKSVEHITDYIKELNANFLSEYSYNITSYKSLFINRLDGSDSKKERQQSLLQLEDFSKDLFNKYLNIAKSKLSSFKDPIEKIMALEIINSDVSRLGSELSSHEKITNIINSTVHDQIDFYFDNLQKTIKEHIHQLNSTLNERRDEVLEGHNLQELSDATSKAIVNDIILLFANLKPFFLPTETQFLSSYQDTIFTKIQVKLQQFFLFLVNIHFLEYLDIIATTSNREQFSGRFLLVLSSICLYFENKGITLVVQLMSEFITVAKQGAKKELNVFSFNAPDLCKRVRETGLQILNVFTRLSSQKLDKILKKGLESIPNNNWLVLKEPRDVRSVNDIYLEEILKFQNETSKLLPVINHHHHSLKSHSRTGSGGNSVSSNNSSSNTPDGHRRNPSASSSSSSNNTNTTLFEKKVDHVDFNTLSVLIAIIKLSLKSFNESLRLKTFGTNGCHQIQIDLHYLKLSLYDLFGSNSFDNLLQECENTVTERCVDPLPLAKSIVSKICETKMNKKKNNEAES
What is the function of this protein?
May act as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN).
What are the official names of this protein?
Vacuolar protein sorting-associated protein 51 homolog, Protein fat-free homolog.
What is the protein family that this protein belongs to?
Belongs to the VPS51 family.
Protein: MSHA_THEFY
Sequence: MASQTPGTEAQSQTVQPGRIAAISLHTSPLDQPGTGDAGGMNVYIVEVAKRLAERGIAVDIFTRATSFEQPPEVELAPGVTVRNIAAGPYGTLDKTALINYLCPFVHGMLRAEAEHLGGSYDLVHTHYWLSGQAGWPVAREWGVPLVHSMHTMARVKNMSLAEGDTPEPEERVRGEDALVALADRLIANTDDEAAQLINYYGASPSRVSTVFPGVDLTTFTPGSRAESLRRLGLPEDTILLLFVGRVQRLKAPDVLLRAAARLLELNPSLRDRLVVAVVGGQSGTGYREPWLLSDLADSLGIADLVRLEPPCPRAELVHYYRAATVTVVPSHSESFGLVAVESQACGTPVVAARVGGLPTAVRDGVSGVLIDGHDPHDYANVLHRMITEPRWRERMGAAGIHHASGLSWESTVDGLLAAYRDALHQCRLTVPCR
What is the function of this protein?
Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
What are the official names of this protein?
D-inositol 3-phosphate glycosyltransferase, N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase, GlcNAc-Ins-P N-acetylglucosaminyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. MshA subfamily.
Protein: RBGP1_HUMAN
Sequence: MDDKASVGKISVSSDSVSTLNSEDFVLVSRQGDETPSTNNGSDDEKTGLKIVGNGSEQQLQKELADVLMDPPMDDQPGEKELVKRSQLDGEGDGPLSNQLSASSTINPVPLVGLQKPEMSLPVKPGQGDSEASSPFTPVADEDSVVFSKLTYLGCASVNAPRSEVEALRMMSILRSQCQISLDVTLSVPNVSEGIVRLLDPQTNTEIANYPIYKILFCVRGHDGTPESDCFAFTESHYNAELFRIHVFRCEIQEAVSRILYSFATAFRRSAKQTPLSATAAPQTPDSDIFTFSVSLEIKEDDGKGYFSAVPKDKDRQCFKLRQGIDKKIVIYVQQTTNKELAIERCFGLLLSPGKDVRNSDMHLLDLESMGKSSDGKSYVITGSWNPKSPHFQVVNEETPKDKVLFMTTAVDLVITEVQEPVRFLLETKVRVCSPNERLFWPFSKRSTTENFFLKLKQIKQRERKNNTDTLYEVVCLESESERERRKTTASPSVRLPQSGSQSSVIPSPPEDDEEEDNDEPLLSGSGDVSKECAEKILETWGELLSKWHLNLNVRPKQLSSLVRNGVPEALRGEVWQLLAGCHNNDHLVEKYRILITKESPQDSAITRDINRTFPAHDYFKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSFLAAVLLLHMPEEQAFSVLVKIMFDYGLRELFKQNFEDLHCKFYQLERLMQEYIPDLYNHFLDISLEAHMYASQWFLTLFTAKFPLYMVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLTDFEGALKFFRVQLPKRYRSEENAKKLMELACNMKISQKKLKKYEKEYHTMREQQAQQEDPIERFERENRRLQEANMRLEQENDDLAHELVTSKIALRKDLDNAEEKADALNKELLMTKQKLIDAEEEKRRLEEESAQLKEMCRRELDKAESEIKKNSSIIGDYKQICSQLSERLEKQQTANKVEIEKIRQKVDDCERCREFFNKEGRVKGISSTKEVLDEDTDEEKETLKNQLREMELELAQTKLQLVEAECKIQDLEHHLGLALNEVQAAKKTWFNRTLSSIKTATGVQGKETC
What is the function of this protein?
May act as a GTPase-activating protein of RAB6A.  May play a role in microtubule nucleation by centrosome.  May participate in a RAB6A-mediated pathway involved in the metaphase-anaphase transition.
What are the official names of this protein?
Rab GTPase-activating protein 1, GAP and centrosome-associated protein, Rab6 GTPase-activating protein GAPCenA.
Protein: IF1A_DICDI
Sequence: MPKNKGKGGKNRRRGKNENEQKRELQFKEEGQEYAQVLRMLGNGRLEASCFDGEKRLCHISGRLRKKEWINNGDIILIQLRDYQNDKADVILRYNVDEARNLKTYGELPETARINETDAFDDVEDIPFEFVAEDDIDIDTL
What is the function of this protein?
Seems to be required for maximal rate of protein biosynthesis.  Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity).
What are the official names of this protein?
Eukaryotic translation initiation factor 1A, eIF-1A, Eukaryotic translation initiation factor 4C, eIF-4C.
What is the protein family that this protein belongs to?
Belongs to the eIF-1A family.
Protein: TSCT1_CAEEL
Sequence: MFIFAAAFQQNTIIMSTTSNEASVIEVVPPNANCDKPKKKFQVVPVPGEFTRGRWKVIDTRFGSAMGEFGNYPPEDEYKMIVTSKNNVITVRKKFPRPTTVTSAPILGAEEADSIRVLQKSQPRFEQVPVTNQIKILIMDPETAVVTAGNTGSTASEVGTDFALTNDMTSSPSSVALLSGDPTKMEDSAKLATATSNTVVAIDNKIVQAMDLVKTHLTFAVREEVETLRTTITDLEARLNALREENRLLRENVSPEVLAFITANKQLCE
What are the official names of this protein?
Protein tsct-1.
What is the protein family that this protein belongs to?
Belongs to the TSC-22/Dip/Bun family.
Protein: XGPT_HISS2
Sequence: MSEKYVVTWDMFQMHTRKLSERLLPATQWKGIIAVSRGGLFPAAVIARELGIRHIETVCISSYDHNQQGNLNVLHAAQVKNGGEGFIVVDDLVDTGNTARAIRELYPNARFVTVFAKPAGANLVDDYVIDIPQNTWIEQPWDMGITFVPPLARK
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi.  To a lesser extent, also acts on hypoxanthine.
What are the official names of this protein?
Xanthine-guanine phosphoribosyltransferase, XGPRT, Xanthine phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NTAL_CHICK
Sequence: MAQPELLWAAAGLMLLGVAVSACVRCQLYATKRGKDGSQGSRLERPQRFEVIRSCSAVTRRPERIKEPEHLARKAPEELSTSCHVGFESSAEPRYQNFLTEDCLHEDAAYVEPVPLDYYSHNRFFSPPNDEDSHSYQNVIIGDPCSSELDDAEDYENSTAIEVWKVQQAKAMLYAESQDEEPDYVNTDPTIDAVVLSK
What is the function of this protein?
Involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells.  May also be involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells.  Couples activation of these receptors and their associated kinases with distal intracellular events such as calcium mobilization through the recruitment of GRB2.
What are the official names of this protein?
Linker for activation of T-cells family member 2, Linker for activation of B-cells, Non-T-cell activation linker.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type III membrane protein. Note=Present in lipid rafts.
Protein: SUCC_SHESW
Sequence: MNLHEYQAKSLFAEYGLPVSEGFACDTAQEAVEAAGRIGGNLWVVKCQVHAGGRGKAGGVKVTGDKEEIRAFAEHWLGKNLVTYQTDEKGQPVAKILVESCTDIANELYLGAVVDRSTRRVVFMASTEGGVEIEKVAEETPELIHKAIIDPLTGPQPYQARDLGFKLGLNPTQMKQFTKIFMGLATMFVDHDFALLEINPLVITTEGNLHCLDGKIGIDGNALFRQPKVKAMHDPSQDDAREAHAAMFELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAEAFKIILSDSNVKAVLVNIFGGIVRCDMIAEGIIGAVKEVGVKVPVVVRLEGTNAELGREVLAKSGLDIIAATSLTDAAERVVKAAEGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.