PharMolix/UniProtQA huggingface dataset:
Protein: ULA1_XENLA
Sequence: MAQVVHIKEQKYDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGLFTIVDGNVVAGEDVGNNFFLQKESIGKNRAQTSMELLQELNDDVTGNFVPESPEQLLDKDPSFFCKFTMVISTQLPESTLLRLAETLWDSNIPLLVCRAYGFVGYMRIIVKEHTVIESHPDNALEDLRLDQPFPELREHLQSYDLDHMERKDHSHTPWIIVVAKYLDKWRSENGGQMPKSYKEKESFRDLIRQGILKNENGVPEDEENFEEAIKNVNTALNITKVSSSVEEILNDDRCTNLTHQSTSFWILARAVKEFMAMEGKGNLPLRGTIPDMIADSDKFIKLQNIYREKAKKDASAVESCVSKLLQSVGRPPESISERDIRLFCRNCAFLRVVRCRSLEEEYGLDTAKKDDIVSLMENPDNEIVLYLMLRAVDRFQKQLGRYPGIYNYQIESDIGKLKSCLNGLLQEYGLSLTVKDEYIQEFCRYGAAEPHTIASFLGGAAAQEAIKIITKQFVIFNNTFIYNAMLQTSATFQL
What is the function of this protein?
Regulatory subunit of the dimeric uba3-nae1 E1 enzyme.  E1 activates nedd8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a nedd8-uba3 thioester and free AMP.  E1 finally transfers nedd8 to the catalytic cysteine of ube2m (By similarity).
What are the official names of this protein?
NEDD8-activating enzyme E1 regulatory subunit, APP-BP1, Amyloid protein-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
Protein: RL17_HERAR
Sequence: MRHRHGLRKLNRTSSHRLAMLRNMTVSLLRHEAIKTTLPKAKELRRVIEPILTLGKTDSLANKRLAFNRLRDREMVVKLFAELGPRYANRNGGYLRILKMGFRAGDNAPMAFIELLDRPETTEAVEDNSGE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: NTPPA_GEOMG
Sequence: MPENSRIVLASASPRRLELLASAGIEFDVFASDIPEEPIPGEAPADFSVRLAKDKAVATAARSEGRWFIGADTIVVCDGEIMGKPADGADAVRMLKKLSGVPHEVITGYAIYDKARDGILCKAVVTKVFFKPLRDEEITAYVATGCPMDKAGAYAIQGGAACMVERIDGSYTNVVGLPLCEVVEDLRTMGAL
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYI_KLEP3
Sequence: MSDYKSTLNLPETGFPMRGDLAKREPGMLARWTDDDLYGIIRAAKKGKKTFILHDGPPYANGSIHIGHSVNKILKDIIVKSKGLTGYDSPYVPGWDCHGLPIELKVEQQYGKPGEKFTAAEFRSKCREYAAEQIDGQRKDFIRLGVLGDWSRPYLTMDFKTEANIIRALGKIIGNGHLHKGAKPVHWCVDCRSALAEAEVEYYDKTSPSIDVAFHAVDKAAVLAKFGVADVNGPVSLVIWTTTPWTLPANRAISLSPEFDYALVQVDGQALILAKDLVESVMKRVGATDYTILAAVQGSELELMRFKHPFLDFDVPAILGDHVTLDAGTGAVHTAGGHGPDDYTISQKYGLEIANPVGPDGAYLPGTYPSLDGINVFKANDIIVEMLRDSGALLHVEKMQHSYPCCWRHKSPIIFRATPQWFVSMDQKGLRAQSLKEIKGVQWIPDWGQARIESMVANRPDWCISRQRTWGVPMSLFVHKETHELHPRTLELMEEVAKRVEVDGIQAWWDLDSRDILGDDADSYEKVPDTLDVWFDSGSTHSSVVDVRPEFAGHAADMYLEGSDQHRGWFMSSLMISTAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVMNKLGADILRLWVASTDYTGEMAVSDEILKRAADSYRRIRNTARFLLANLNGFDPAKDMVKPEEMVVLDRWAVGCAQAAQEDILKAYESYDFHEVVQRLMRFCSIEMGSFYLDIIKDRQYTAKADSVARRSCQTALFHIVEALVRWMAPIMSFTADEIWGYLPGDREKYVFTGEWYKGLFGLADDEAMNDGFWDELLKVRGEVNKVIEQARADKKVGGSLEAAVTLYADADLAAKLNALGDELRFVLLTSGANVADYAQAPADAWQSDLLKGLKVVLSKAEGEKCPRCWHYTSDVGKVAEHAEICGRCVSNVAGNGEQRKFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDIA6_PONAB
Sequence: MALLVLGLVSCAFFLEVNGLYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGQSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQKGESPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIISEDIAKRTCEEHQLCVVSVLPHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFGYPAMAAINARKMKFALLKGSFSEQGINEFLRELSFGRGSTAPVGGGAFPTIVEREPWDGRDGELPVEDDIDLSDVELDDLGKDEL
What is the function of this protein?
May function as a chaperone that inhibits aggregation of misfolded proteins.  Negatively regulates the unfolded protein response (UPR) through binding to UPR sensors such as ERN1, which in turn inactivates ERN1 signaling.  May also regulate the UPR via the EIF2AK3 UPR sensor.  Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin.
What are the official names of this protein?
Protein disulfide-isomerase A6.
What is the protein family that this protein belongs to?
Belongs to the protein disulfide isomerase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen. Cell membrane. Melanosome.
Protein: CEMA_MARPO
Sequence: MKKNFSYWRIFHHIFALPYCSLEKAYKASKRIQKIKKDYFLYKNILFSSKRSWQSILFYIDTELNNSVFKIYLSLLEYKLSLWLIQLFLIFSLFFKKNSKFDLILPNINEKKKKRKINRKLAWIRATLNDLESWRRYYLFSSFLSLDKKEKNNFSFLQMKSSRLTAIAYESIGLVPRSITRTFSRFKAELTNQSSSLVLKEFRLAKYQALASLQYIGCLFFIPLGVSFFFQKCFLEPWIQNWWNIYQSQIFLTSFQEEKALKKLQEIEELFWLDKVMTYSSNKIQLQDLTKEIHQQTIELVQIYNNDSIKIVLHLLTDLIWFITLSCLFILGKERLVILNSWAQELFYSLSDTMKAFFILLLTDLCIGFHSPHGWEIVISSCLEHFGFVHNKHVISCFVSTFPVILDTVFKYLIFRHLNRISPSIVATYHTMNE
What is the function of this protein?
May be involved in proton extrusion.  Indirectly promotes efficient inorganic carbon uptake into chloroplasts.
What are the official names of this protein?
Chloroplast envelope membrane protein.
What is the protein family that this protein belongs to?
Belongs to the Cema family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: SELO_ERWT9
Sequence: MQFNNTWLNELNGFHTTLRPMPLKNARLLYYSAELAQDLGLDERLFDAQNVGLWSGERLAEGMQPLAQVYSGHQFGVWAGQLGDGRGLLLGEQQLPDGRKFDWHLKGAGLTPYSRMGDGRAVLRSTLREFLAGEAMYHLGIPTSRALTVVTSDEPVYRETTEAGAMLLRVAESHVRFGHFEHYYYQGQTEKVTQLADYVIRHHWPELVQEKDRYLLWFSDVVQRTARMIAGWQSVGFAHGVMNTDNMSILGLTFDYGPYGFLDDYRPDLICNHSDHQGRYSFENQPMIGLWNLNRLAHALSGLMSPQQLKQALAGYEPELMRCWGEKMRAKLGLLTPAKDDNNILTGLLSLMTKEGSDYTRTFRQLSQSEQLQLRSPMRDEFIDRDAFDSWYNVWRQRVLQEERSDEERQQTMKLANPALVLRNYLAQQAIERAEQDDISVLARLHQALSRPFDDAPEYADLAQRPPDWGKKLEVSCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: ATPB_BACP3
Sequence: MTRGRVIQVMGPVVDVKFENGHLPAIYNALKIQHKARNENEVDIDLTLEVALHLGDDTVRTIAMASTDGLIRGMEVIDTGAPISVPVGQVTLGRVFNVLGEPIDLEGDIPADARRDPIHRPAPKFEELATEVEILETGIKVVDLLAPYIKGGKIGLFGGAGVGKTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYHEMKDSGVISKTAMVFGQMNEPPGARMRVALTGLTMAEYFRDEQGQDGLLFIDNIFRFTQAGSEVSALLGRMPSAIGYQPTLATEMGQLQERITSTAKGSITSIQAIYVPADDYTDPAPATTFSHLDATTNLERKLAEMGIYPAVDPLVSTSRALAPEIVGEEHYQVARKVQQTLERYKELQDIIAILGMDELSDEDKLVVHRARRIQFFLSQNFHVAEQFTGQPGSYVPVKETVRGFKEILEGKYDHLPEDRFRLVGRIEEVVEKAKAMGVEV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SDF2B_DROWI
Sequence: MLRQILSSAVAKSTRGLSFTVNRLASNLDKSEYTTPGEIIDYDDPTHLPVPEYPLRPDEPLETRKQRLLYQSRKRGMLENDLLLSTFVAKYLRDFNADQTAQYDKLINGVSNDWDIFYWATETKATPAEYDNEIMQMLKQHVKNEERVQRIRQPDL
What is the function of this protein?
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.
What are the official names of this protein?
Succinate dehydrogenase assembly factor 2-B, mitochondrial, SDH assembly factor 2-B, SDHAF2-B.
What is the protein family that this protein belongs to?
Belongs to the SDHAF2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RS5_STRR6
Sequence: MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGRVGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGSGVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISVSDLA
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: APOC4_COLGU
Sequence: MSLLRNRLQDLPALCLCVLVLACIGACQSEAHEETPSPPPKLKMSHWSLVTGRMKELLEPVVNRTRDRWQWFWSPSTFRGFMQTYYDDHLRDLGPRTKAWLLKSKDSLLNKTHSLCPRIVCGDKDQG
What is the function of this protein?
May participate in lipoprotein metabolism.
What are the official names of this protein?
Apolipoprotein C-IV, Apo-CIV, ApoC-IV, Apolipoprotein C4.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein C4 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RECX_STAA9
Sequence: MPKITKIEVQKKNKERFNLFLDEQFEMGIDIDTLVKFNLKKGQQLEAADMAEIQKYDHYRIGLNKAIQYLSYKKRTEKEVIQYLQKEEISEQAISEVIEYCYREKLIDHQDYAESLKNTMIRTTDKGPKIYQQKLYQLGIEPNIIEMFTELYREQQELDDIIQIAEKISKTKKGPQNKVKEKVMQSLIQKGFEMETIHAVLNEMDFTQDEAVLDDLLQRDLEKIYNKNRKKYTQQKLISKTIEGLMRKGYKYDKIKAKLEESGIADGTEEIE
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRB_PSEE4
Sequence: MQKIDKTLEEWRAMLDPAQYQVCRLKGTERPFSGKYNSERRDGVYHCICCDLPLFDSKAKFDSGCGWPSFYEPIEEAAMIEIRDTSHGMIRTEVTCAQCDAHLGHVFPDGPPPTGLRYCINSVCLDLKPRD
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: SYFB_COLP3
Sequence: MKFSESWLREWVNPALSSDDLAHQITMAGLEVDGVDPVAGEFSGVVIGEVVECGPHPDADKLQVTKISLGDYSSTTVEKGELVTIVCGAKNCRLGLKVAVATVGAVLPGDFKIKKAKLRGVPSFGMLCSESEIGLADDSDGIMELASDAPLGQCVREYLDLNDVTIDVDLTANRGDCLGLKGLAREVGVLNSLEVSEPTITAVAPTIDDVITINIEANEACPRYLGRVIKGINPNATTPLWMVEKLRRCGTRSIDPVVDVTNYILLELGHPMHAFDLAKLDGGINVRFANKDEKLTLLDENEVTLKEGTLVIADENKALAMAGIFGGLESGVTNNTTDLFLESAFFAPLAILGKARQYGLHTDSSHRYERGIDPTLQHDAIERATELLLSIVGGQAGPVVEAKSDADIPQTKDVNLRRKMLDSRIGHHIEDAQVSEILTRLGFTVTTTGEGEAKVWQVIVPAYRFDIKIEVDLIEEVARIFGYNNIPNIAPKATLKMCEQKEANLSLSNLKQTLVNRDYQEAITYSFVDPKVQALLHPGQEVMTLPHPISSEMSVMRLSLWTGLLQSMVYNQNRQQGRIRLFETGLRFVPDESAENGVRQQNMIAGVISGLRVDEHWSMEKAATDFYDIKGDVEALLALTCDAQGYEFSKAEVDALHPGQTAQITKNGVFVGCVGTLHPELERKLGLNGRTLIFELLLSEVLVQKIPEATDISRFPANRRDLAIVVKEDVDAKNVLQLIEKVGGNYLIDLNLFDVYKGQGIDDGFKSLAIALVLQDTSKTLEEKDITDVIDRVVATLKTELNASLRD
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_TERTT
Sequence: MAIEKTLSIVKPNAVKKNVIGDIYSRFEKAGLKIVAAKMTQLDDDRAGGFYEEHKARPFFGELVEFMTSGPVLIQVLEGENAVALNREIMGATNPENAAEGTIRKDFADSLSENAVHGSDSTESAAREIAYFFDAAEIFSR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHS_RHOPA
Sequence: MNRLSASERQAALRELPGWLELEEREAIGRSYQFKDFSEAFGFMTRVALAAEKADHHPEWRNVYRTVDVVLTTHDAGGVTERDVKLAKAMDAIAERCGAR
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: MIAA_ECOSE
Sequence: MSDISKASLPKAIFLMGPTASGKTALAIELRKILPVELISVDSALIYKGMDIGTAKPNAEELLAAPHRLLDIRDPSQAYSAADFRRDALAEMADITAAGRIPLLVGGTMLYFKALLEGLSPLPSADPEVRARIEQQAAEQGWESLHRQLQEVDPVAAARIHPNDPQRLSRALEVFFISGKTLTELTQTSGDALPYQVHQFAIAPASRELLHQRIEQRFHQMLASGFEAEVRALFARGDLHTDLPSIRCVGYRQMWSYLEGEISYDEMVYRGVCATRQLAKRQITWLRGWEGVHWLDSEKPEQARDEVLQVVGAIAG
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: UFOG_HORVU
Sequence: MAPPPPHIAVVAFPFSSHAAVLFSFARALAAAAPAGTSLSFLTTADNAAQLRKAGALPGNLRFVEVPDGVPPGETSCLSPPRRMDLFMAAAEAGGVRVGLEAACASAGGARVSCVVGDAFVWTADAASAAGAPWVAVWTAASCALLAHLRTDALRRDVGDQAASRADELLVAHAGLGGYRVRDLPDGVVSGDFNYVISLLVHRQAQRLPKAATAVALNTFPGLDPPDLIAALAAELPNCLPLGPYHLLPGAEPTADTNEAPADPHGCLAWLDRRPARSVAYVSFGTNATARPDELQELAAGLEASGAPFLWSLRGVVAAAPRGFLERAPGLVVPWAPQVGVLRHAAVGAFVTHAGWASVMEGVSSGVPMACRPFFGDQTMNARSVASVWGFGTAFDGPMTRGAVANAVATLLRGEDGERMRAKAQELQAMVGKAFEPDGGCRKNFDEFVEIVCRV
What is the function of this protein?
In the presence of other necessary color factors, this glycosylation reaction allows the accumulation of anthocyanin pigments.
What are the official names of this protein?
Anthocyanidin 3-O-glucosyltransferase, Bronze-1, Flavonol 3-O-glucosyltransferase, UDP-glucose flavonoid 3-O-glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: PYRC_ECOLU
Sequence: MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHDFSPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRNGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVKQ
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: YBK0_YEAST
Sequence: MLFKPKTRAIPSPTARTLPVSFKLASSDTPLILSSKMEETSVGCALVEANLLVEAKAAAAGLAALVELIRVLDRERIAAVRANIIICACFFYLFCYCSCDSYES
What are the official names of this protein?
Putative uncharacterized protein YBL100C.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MDTK_SALPK
Sequence: MQKYTSEARQLLALAIPVILAQVAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLVMIVLWNAGYIIRSMHNIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFLGLLVNIPVNYIFIYGHFGMPELGGIGCGVATAAVYWVMFIAMLSYIKHARSMRDIRNEKGFGKPDSVVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLGVGICMAVVTAIFTVTLRKHIALLYNDNPEVVALAAQLMLLAAVYQISDSIQIIGSGILRGYKDTRSIFFITFTAYWVLGLPSGYILALTDLVVDRMGPAGFWMGFIIGLTSAAVLMMLRMRYLQRQPSAIILQRAAR
What is the function of this protein?
Multidrug efflux pump that functions probably as a Na(+)/drug antiporter.
What are the official names of this protein?
Multidrug resistance protein MdtK, Multidrug-efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CST12_RAT
Sequence: MLWKSVLPVALIVLGIHDCSFKFIEIDKNEEEFAMSMEHVLFHFNENQNDDFAYKFLRVRRSLRKKYTQKYLVDLEMGRTLCGKYDEDIDNCPLQEGPGEKKVRCTYIVETRVWVTEFTILNSTCVQT
What is the function of this protein?
May play a specialized role in spermatogenesis.
What are the official names of this protein?
Cystatin-12, Cystatin TE-1.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRAK2_HUMAN
Sequence: MSQSQNAIFTSPTGEENLMNSNHRDSESITDVCSNEDLPEVELVSLLEEQLPQYRLKVDTLFLYENQDWTQSPHQRQHASDALSPVLAEETFRYMILGTDRVEQMTKTYNDIDMVTHLLAERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQAFDQVNQLQHELCKKDELLRIVSIASEESETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRSRSGPTAHLYFSQSYGAFTGESLAAEIEGTMRKKLSLDEESSLFKQKAQQKRVFDTVRIANDTRGRSISFPALLPIPGSNRSSVIMTAKPFESGLQQTEDKSLLNQGSSSEEVAGSSQKMGQPGPSGDSDLATALHRLSLRRQNYLSEKQFFAEEWQRKIQVLADQKEGVSGCVTPTESLASLCTTQSEITDLSSASCLRGFMPEKLQIVKPLEGSQTLYHWQQLAQPNLGTILDPRPGVITKGFTQLPGDAIYHISDLEEDEEEGITFQVQQPLEVEEKLSTSKPVTGIFLPPITSAGGPVTVATANPGKCLSCTNSTFTFTTCRILHPSDITQVTPSSGFPSLSCGSSGSSSSNTAVNSPALSYRLSIGESITNRRDSTTTFSSTMSLAKLLQERGISAKVYHSPISENPLQPLPKSLAIPSTPPNSPSHSPCPSPLPFEPRVHLSENFLASRPAETFLQEMYGLRPSRNPPDVGQLKMNLVDRLKRLGIARVVKNPGAQENGRCQEAEIGPQKPDSAVYLNSGSSLLGGLRRNQSLPVIMGSFAAPVCTSSPKMGVLKED
What is the function of this protein?
May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR.
What are the official names of this protein?
Trafficking kinesin-binding protein 2, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein.
What is the protein family that this protein belongs to?
Belongs to the milton family.
What are the subcellular locations of this protein?
Cytoplasm. Early endosome. Mitochondrion. Note=Colocalizes with MGARP at the mitochondria. Translocates from the cytoplasm to the mitochondria in a MGARP-dependent manner (By similarity).
Protein: LPXB1_LEGPA
Sequence: MPNASRVVIVAGEESGDHHAAELVKQLKAVYPNLKISGIGGKHLRAAGVHLISDLTRYAVTGLTEIIPFLKIFHKAFQDIKQHLSTQKPDLLILVDYPAFNLRLAKYAKKKLGLKIIYYISPQIWAWKGKRIHLIKDSIDKMAVIFPFEKTIYENAGVPVSFVGHPLVKKIASAKDKHSSRTFLGLPLDEPIIALLPGSRHSEIERHIPILVNTAKLLTLDNPKLRFVVPIAGTINPDKVKAYFSNQNLTVTFIQGQAIECMSAADFVIVASGTASLECALLEKPMCIIYKSSFLTYVAAMYFIKVKFLGLCNLLANKMMVPEFLQYDCNEIELSRYISNFHSDPNQPKSMINQLAKLKESLSSSQADCSLFDLVVAELPEKNA
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase 1.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: MATK_KALBU
Sequence: MEQFKIDLNLGRSQQHDFIYPLIFQEYIYALAHDRGLNRSIFLENAGYDNKFSLLIVKRLITHLITQMYQQNHFLFSVNDSNQKKILGYNTNLYSQMIFEGFAVVVEIPFYLRLLSFLEGKERMKSHNLRSIHSIFPFLEDKFAFLNYVLDIQIPHPIHLEILIQTLRYWVKDASSLHLLRFFLHEYPIWNSFLIRKKSSFSFSKRNQRFFFFLYNFHVCEYESIFVFLRNQSSHLRSISYETFLERISFYRKIELEEVFTKDFKAILWVFKEPFLHYVRYRGNALLASKGTSLLMNKWKHYIVNFWQCYFYIWSQPRRIDINQLSNHSLDFLGYLSSVRLKHLMVRSQMIENSFLIENASKKFDTLMPITPMIGSLSKAKFCNVLGHPMSKPAWSALSDSDIIERFGCIYRNLSHYYSGSLKKRNLYRIKYILRLSCARTLARKHKSTVRLFLKRLGMGLLEEFFTGEEQVFYLTLPKASSTSGELYRRRVWYLDIICINHISNYE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SAHH_MYCTO
Sequence: MTGNLVTKNSLTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISGSLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWKGETLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAEWKVFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSVTKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEIDPINALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNEIDMAGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFANQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEGPYKPDHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENPL_PONAB
Sequence: MRALWVLGLCCVLLTFGSVRADDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALSGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFCSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADDKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPTDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDESEKTKESREAIEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRIKEDEDDKTVLDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNIDPDAKVEEEPEEEPEETTEDTTEDTEQDEDEEMDVGTDEEEQETAKESTAEKDEL
What is the function of this protein?
Molecular chaperone that functions in the processing and transport of secreted proteins.  When associated with CNPY3, required for proper folding of Toll-like receptors.  Functions in endoplasmic reticulum associated degradation (ERAD).  Has ATPase activity.  May participate in the unfolding of cytosolic leaderless cargos (lacking the secretion signal sequence) such as the interleukin 1/IL-1 to facilitate their translocation into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) and secretion; the translocation process is mediated by the cargo receptor TMED10 (By similarity).
What are the official names of this protein?
Endoplasmin, Heat shock protein 90 kDa beta member 1.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen. Sarcoplasmic reticulum lumen. Melanosome.