PharMolix/UniProtQA huggingface dataset:
Protein: UREF_YERPS
Sequence: MNASDLIRIMQFGDSVLPVGAFTFSNGVESAIQTGIVHDVATLKGFVLTALKQAASCDGMGVVAAHRAVVADDRDGIIRADWAVNNRKLNEESRLMATRMGKKLAEMSIHVVEHPLISWWLEQIKNGNTAGTYPVTQAVVMAAQGIGQREVVVMHQYGVAMTILSAAMRLMRVTHFDTQHILFELNHDIEKFCDIAEIGDINQMSSYVPIVDVLAAVHVKAHVRLFSN
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTK_PROMH
Sequence: MQKYIKEARSLLALGIPVIIAQFSQTAMGVVDTVMAGAVNATEMSAVAVGTSIWLPTILLGQGILMALTPIVAQLNGSGQRKHIANRTQQGFWLATFLSIMVIAILYNSRFIIEAQHDIEPELAEKAIGFIHAIMWGAPGCLYYQVLRSQCEGLSKTKPGMIIGFIGLLINIPVNYAFIYGKFGAPQLGGIGCGVATASVFWAMFLMMRYYVRRAPTQRDVMPKKRLVLPEFHTIKRITLLGLPVGLALFFEVTLFAVVALLVSPLGVTAVASHQIALNFSSLMFMFPLSLGIAATIRVGYNLGQRSTEQARTSAITALAVGLMLASCTAIFSIIFREKIALMYNDNIEVVTLASHLMLFAALYQLSDSVQVIGSGVLRGYKDTRSIFFITFIAYWVIGLPSGYLLGRTDYIVEAMGPAGFWIGFILGLTASAIMMGTRIWWIQRQSDEVVLLRSER
What is the function of this protein?
Multidrug efflux pump that functions probably as a Na(+)/drug antiporter.
What are the official names of this protein?
Multidrug resistance protein MdtK, Multidrug-efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VM2_TRIST
Sequence: MIQVLLVTICLAVFPYQGNSIILESGNVNDYEVVYPRKVTALPKGAVQPKYEDAMQYEFKVNGEPVVLHLEKNKGLFSEDYSETHYSPDGREITTYPSVEDHCYYHGRIQNDADLTASISACNGLKGYFKLQGETYLIEPLKLPDSEAHAVFKYENVEKEDEAPKMCGVTETNWESDEPIKKASQLNLTPDEQRFIELVIVADHRMYTKYDGDETEISSKIYEIANDLNVIFRALYIHVALIGLEIWPSGELCNVTLSADDTLDSFAEWTKRDLQKRKRHDNAQLLTGMIFNEKIEGRAYKKTMCHWKRSVGIVRDHRTRPHFVANRMAHGLGHNLGINHDGDSCTCGANSCIMSATVSNDPSSRFSDCSLNQYSSDIIHNPYTSRCLYNGPWKTDIVSPPVCGNYYVEVGEDCDCGPPANCQNRCCDAATCRLTPGSQCAEGLCCEQCRFSTEGKLCREAKGDWNNDYCSGQSGDCPRNPFRA
What is the function of this protein?
Snake venom zinc metalloproteinase that inhibits ADP-induced platelet aggregation in human platelet-rich plasma (IC(50) is 175 nM) and cleaves alpha-(FGA) and subsequently the beta-chain (FGG) of bovine fibrinogen, leaving the gamma-chain unaffected.  It is also able to inhibit proliferatin of ECV304 cells by inducing apoptosis of these cells.
What are the official names of this protein?
Zinc metalloproteinase-disintegrin stejnitin, Snake venom metalloproteinase, SVMP.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-II subfamily. P-IIb sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TX1_GRARO
Sequence: YCQKWMWTCDSKRKCCEDMVCQLWCKKRL
What is the function of this protein?
Inhibits voltage-gated sodium channels Nav1. 1/SCN1A (IC(50)=630 nM), Nav1. 2/SCN2A (IC(50)=230 nM), Nav1. 3/SCN3A (IC(50)=770 nM), Nav1. 4/SCN4A (IC(50)=1290 nM), Nav1. 6/SCN8A (IC(50)=630 nM), Nav1. 7/SCN9A (IC(50)=15. 3-1000 nM) and potassium channels Kv11. 1/KCNH2 (IC(50)=4. 2 uM).
What are the official names of this protein?
Beta-theraphotoxin-Gr1a, Beta-TRTX-Gr1a, GrTx1.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 30 (phrixotoxin) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RECO_BIFLO
Sequence: MSLYRDEGVVLRTSKLGEADRIITILTRGHGKIRAVAKGVRRTKSRFGARLEPFMRVDVLIAEGRSLDVVSQAEAVAAYGAPIAADYAAYEAANVIVETIDKIASTEHEQLPNQYRLLIGALNALAKQSHAPQAIGDSYVMRALALAGWTPRLGTCVVCGKAEPAYLSIASGGVMCEADHTTDARRIAPFVLNQFDALIRGDWSVLDAAPVERVVQELVEDWGEYYLERPIRSLRLIDS
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: Y8137_DICDI
Sequence: MSALGRNLGNFIQTFSNKTSSIKTVNGLKRGLLPCCGSTVRPIAKDNHHQSPVLNVNRSSISGIRTELFNSNGLITQFQVRQYCSESKLQVSPTPKTLLSEICQREITDFKTIFEDNNNEVDSFLEEFGFELTKEGDQALLKKTFADGTNIVIRFETLEQPIEEDFDEQDENDQNERDEDDAEEQEEDEVEEEEEEQQEEEEGENDEELTEGAEEDSHEHPFEIEVTPKGNASGKLTFGCYASHDGNYTVSGFYKGGFGETVNPVDIGGTSMEFQDNILLVLQQYGINERLSFFIHDYVHNKKINDYVESFEALKDFVSKE
What are the official names of this protein?
Putative uncharacterized protein DDB_G0288137.
Protein: RUVA_SYNSC
Sequence: MVGWLKGLIVYKLQRGNRSQITLNCNGVGYEVQITQREWLTLENDQTIQLWIHQSISADNWQFFGFKSTQERDIFRELISVNGVGPQAGMALMQECKSQELVEAISNGDLRRLCKAQGIGKRTAERLAVELRASIAAFAGMDPAPSLAEGVSSEQMPESGADVEATLSMLGYDDLEVRRAIRAIAEGSDGPPPPGDDQDAWLRGCLQWLSRDSA
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: AKIP_MOUSE
Sequence: MFLARLTSRLARTVVPWAGFSRSCPGSGVIGSYAFRPLYSLQPASPSRAASLPGKRTQSELEEFLVPRKMAISPLESWLTAQYLLPRRNVEVPVTLAPSQFYECPPRQGEEEAQQGVREAWDATPVQCKNVLKIRRRKMNHHKYRKLVKRTRFLRRKVREGRLKKKQIKFEKDLKRIWLKAGLKEAPENWQTPKIYLKNK
What is the function of this protein?
May act as a negative regulator of Aurora-A kinase, by down-regulation through proteasome-dependent degradation.
What are the official names of this protein?
Aurora kinase A-interacting protein, AURKA-interacting protein, 28S ribosomal protein S38, mitochondrial, MRP-S38.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mS38 family.
What are the subcellular locations of this protein?
Mitochondrion. Nucleus.
Protein: EGTU_HELPG
Sequence: MLGMGVFKQLIKELYEWLLHSMDMATQHLVAIVLKISVVKYLIKEFHDRFIYFIDLLAQHFIIVALSGFLVLVFGVLIGVFAFYNSKARAFLLPVVNFLYTIPSLALFALFIPVIGVGLKNALLVLVLYGLLPIVYSTYNALKEVREEVIKAAIGLGCNPKELFFRVHFLLAIPQILAGLRIAVVMLVAMAGIGALIGAGGLGQAIFRGLNTQNTTLLVAGSLIIALFSVLADKFVSVFQHENALQRLFSQNATQKQKRRVYTNLAVFLFLLLASALWLIPRNAIEEKPLVVATKPSSEQYILGEILSLLLEKHHIPIKRAFGIGGGTMNIHPALIRGDFDLYMEYTGTAWVNTLKNPLTQKVDFETIKKRYEKEFNLLWVGLLGFNNTYSLAISKEDAQKYAIETFSDLALHSQNFDFGAEFDFFEREDAFKGLMKAYRFHFRSLHEMDINLRYKSFESHKINALDVFTTDAQIKELDLKVLKDDKGFFPNYQAGIVIRKEIIKKYPEALKILEKLDSKINDETMQDLNYQVEVLKKSPKIVAKDFLERLGL
What is the function of this protein?
Part of the ABC transporter complex EgtUV involved in the uptake of ergothioneine (EGT), a natural low-molecular weight (LMW) thiol antioxidant which protects H. pylori against bleach stress (PubMed:36347253).  Responsible for the translocation of the substrate across the membrane (Probable).  Also contains a C-terminal periplasmic solute-binding domain (SBD) which binds to ergothioneine with low-micromolar affinity (PubMed:36347253).  Cannot bind the structurally similar compounds glycine betaine, choline, proline, carnitine or histidine (PubMed:36347253).
What are the official names of this protein?
Ergothioneine transport permease/ergothioneine binding protein EgtU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the OsmX family.
Protein: RL331_STAAN
Sequence: MRVNVTLACTECGDRNYITTKNKRNNPERVEMKKFCSRENKQTLHRETK
What are the official names of this protein?
50S ribosomal protein L33 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RL7_ECO24
Sequence: MSITKDQIIEAVAAMSVMDVVELISAMEEKFGVSAAAAVAVAAGPVEAAEEKTEFDVILKAAGANKVAVIKAVRGATGLGLKEAKDLVESAPAALKEGVSKDDAEALKKALEEAGAEVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: ATPB_THISH
Sequence: MSAGNIVEIIGAVVDVEFPRDAVPNVYDALRVEDSGLTLEVQQQLGDGVVRTIAMGSTDGMRRGVTVANTGAPISVPVGKGTLGRVMDVLGNPVDNAGDVQTEERWSIHRPAPSFDEQAGSTELLETGIKVIDLLCPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMKDSNVLDKVALVYGQMNEPPGNRLRVALTGLTMAEFFRDEGRDVLMFIDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKKGSITSIQAVYVPADDLTDPSPATTFAHLDATVVLSRQIAELGIYPAVDPLDSTSRQLDPQVIGNEHYDTARAVQNTLQRYKELKDIIAILGMDELSEDDKLIVARARKIQRFLSQPFFVAEVFTGAPGKYVSLKDTIRGFQAIVAGEYDHLPEQAFYMVGTIDEAVEKAGKLK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS8_DANRE
Sequence: MGISRDNWHKRRRTGGKRKPVHKKRKYELGRPAANTKIGPRRIHTIRVRGGNKKYRALRLDVGNFSWGSECCTRKTRIIDVVYNASNNELVRTKTLVKNCVVLVDSTPYRQWYESHYALPLGRKKGAKLTPEEEEILNKKRSKKVQKKFTLRRKTAKISPLLEEQFLQGKLLACISSRPGQCGRADGYVLEGKELEFYLRKIKAKKGK
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
40S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS8 family.
Protein: RL29_SALAR
Sequence: MKAKELREKSVEELNTELLNLLREQFNLRMQAASGQLQQSHLLKQVRRDVARVKTLLTEKAGA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: MCH1_EMENI
Sequence: MTGSIGQAPAIDKRDFDINRRSSTPHETAAQEDEALLHSRPRSRLSVGNRFSDNDDGLLSDVVEEIVERDRQRMRREVVRVGSFVWGVITCLGAGSITAFSLYGPLLLTRLNYTQLRVNEVSIAAGISMYLPVSLAGYLCDRYSPSPLTLFAGIAFGLGYSLAAFVYKSGPPPDAGGNGWPFWVMVVAFIAIGVATCSMYLAAVTTCAKNFGRGKHKGIILAVPIAAFGLSGMWQSQVGTYFLCERLKDSNCGDVDVYKYFLFLAILLLTIGVIGTFALRIVDDEEEKYIDEAVEELERSGLLAESEFFRPRSEVQAAYGTFSDDHEDNGSVDDQSVTISEELREAARREKEREEEERRKKNWLLNYETRIFLADHTMWWLALGFFLVTGPGEAYLNNLGTIVQTLNLDTTAIVDSHPAGLPSTHVTIIALTSTIARLLTGSLSDLFAPTARRHFTVDQETAGPDPFTKQRPALSRLAFLIPSALLLSLGFLLLASPLPTHHPELSHLTTALVGLGYGSIFSLVPIIISVVWGVENFGTNWGIVAMFPAAGAAMWGVIYSRAYQSAADGSPTDDGQCHGWKCFGFWSIGCTFSVWVAIVAWLVAWTSWRRRGVVV
What is the function of this protein?
Probable transporter.
What are the official names of this protein?
Probable transporter mch1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: GPMI_AYWBP
Sequence: MTKKFVGLIILDGLGLTDQKENNAFHLAKTPYLDYLLKNFPNTTLKASGEEVGLPQGQMGNSEVGHLNLGAGRVVYQSLTQINKAIRDKTFFTNKQFLQAIEHVKKNNSKIHLLGLISDGGIHSHLDHFKALFDLLKENNLANNTFLHAFTDGRDTGTHSGINYIKNLLDYGFNIASVAGRYYALDRDNNWDRINLVYNMLTSKQAPVITLSLEKTMQNFYNQGITDEFITPFITDPNGLIDDNDAVIFVNFRPDRAMRLATALSNPCATNAFCSEGKTNFCGNKLVNNLFLVTMTQYNVQVKSVVAFEKKTLKNIYGEVIANLGMHQLRISETEKYPHVTFFFDGGKELQLKNADRILIPSPKVKTYDLKPEMSALEITNAAKTAIFSRKYDTLILNFANPDMVGHTGFLDATIKAVQTVDSCLKEVLNAIFAVKGKACIVADHGNAEKMKDNQGNPHTAHTTNLVPFIVTDKNVVLKPGSLCDVAPTMLDLLEIKKPQEMTGNSLIKKLV
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: PEPVL_STAAR
Sequence: MWKEKVQQYEDQIINDLKGLLAIESVRDDAKASEDAPVGPGPRKALDYMYEIAHRDGFTTHDVDHIAGRIEAGKGNDVLGILCHVDVVPAGDGWDSNPFEPVVTEDAIIARGTLDDKGPTIAAYYAIKILEDMNVDWKKRIHMIIGTDEESDWKCTDRYFKTEEMPTLGFAPDAEFPCIHGEKGITTFDLVQNKLAEDQDEPDYELITFKSGERYNMVPDHAEARVLVKENMTDVIQDFEYFLEQNHLQGDSTVDSGILVLTVEGKAVHGMDPSIGVNAGLYLLKFLASLNLDNNAKAFVAFSNRYLFNSDFGEKMGMKFHTDVMGDVTTNIGVITYDNENAGLFGINLRYPEGFEFEKAMDRFANEIQQYGFEVKLGKVQPPHYVDKNDPFVQKLVTAYRNQTNDMTEPYTIGGGTYARNLDKGVAFGAMFSDSEDLMHQKNEYITKKQLFNATSIYLEAIYSLCVEE
What are the official names of this protein?
Putative dipeptidase SAR1836.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family.
Protein: MLEN_BACSU
Sequence: MKDVRLPTLFEIIIVLGVFLALVLSFTVFLDLPIQLALFVSWFIAMLLGIRLGYSYKDLQNAIVHGISNGLEAVLILVSVGALIGTWIAGGVVPTLIYYGLEFIHPSIFLLATLIICSIMSVATGTSWGTVGTAGIAMIAIGEGLGIPLPLVAGAILSGAYFGDKLSPLSDSTVLASSLSKVDVLAHVRAMLYLSIPAYVITAILFTVVGFMYGGKNIDLDKVEFLKSSLQNTFDIHIWMLIPAVLVIVLLAMKKPSMPVIVIGALLGAIWAVVFQGMDIAHAIATAYNGFSIKTDVEFLNGLLNRGGIVGMLDSLVVIIFGLGFGGLLEKLGVLKVIVSTFEKKLTSAGNVTLSTLIVAFLANIFGCAMYVSLILTPKIMEDSYDRLHLDRRVLSRNSEVGGTLTSGMVPWSDNGIYMAGILGVSTFSYLPFMWLSFVAIGLAIIYGYTGKFIWYTKNNTVKAEKLG
What is the function of this protein?
Couples proton uptake and Na(+) efflux to the substrate-product malate/lactate antiport, in an electroneutral malate-2H(+)/Na(+)-lactate exchange.  Plays a role in supporting growth to high density on malate at reduced protonmotive force.
What are the official names of this protein?
Malate-2H(+)/Na(+)-lactate antiporter.
What is the protein family that this protein belongs to?
Belongs to the NhaC Na(+)/H(+) (TC 2.A.35) antiporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GLRX2_ECTVM
Sequence: MKNVLIIFGKPYCSICENVSEAVEELKSEYDILHVDILSFFLKDGDSSMLGDVKRGTLIGNFAAHLSNYIVSIFKYNPQTKQMAFVDINKSLDFTKTDKSLVNLEILKSEIEKATYGVWPPVTE
What is the function of this protein?
Glutaredoxin necessary for virion morphogenesis and virus replication.  Functions as a thiol-disulfide transfer protein between membrane-associated OPG128 and substrates OPG095 or OPG053.  The complete pathway for formation of disulfide bonds in intracellular virion membrane proteins sequentially involves oxidation of OPG072, OPG128 and OPG088.  Exhibit thioltransferase and dehydroascorbate reductase activities in vitro.
What are the official names of this protein?
Glutaredoxin-2.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: RR16_GRATL
Sequence: MLKIRLKRFGRKRQPSYRIIVIDSRKPRDGRPIEEIGFYSPLNNKSKINLIQVKKRIYQGAQPTKKVQQIISQFEKQN
What are the official names of this protein?
30S ribosomal protein S16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TPIS_PYRAB
Sequence: MELKEPIIAINFKTYIEATGKRALEIAKAAERVWKDTGVTIVVAPQLVDLRMIAENVEIPVFAQHIDPIKPGSHTGHVLPEAVKEAGAVGTLLNHSENRMILADLEAAISRAKEVGLITMVCSNNPAVSAAVAALDPDYVAVEPPELIGTGIPVSKAKPEVITDTVELVRKVNPKVKVLCGAGISTGEDVKKAIELGTVGVLLASGVTKAKDPEKAIRDLVSGIIRKD
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S35E3_HUMAN
Sequence: MALLVDRVRGHWRIAAGLLFNLLVSICIVFLNKWIYVYHGFPNMSLTLVHFVVTWLGLYICQKLDIFAPKSLPPSRLLLLALSFCGFVVFTNLSLQNNTIGTYQLAKAMTTPVIIAIQTFCYQKTFSTRIQLTLIPITLGVILNSYYDVKFNFLGMVFAALGVLVTSLYQVWVGAKQHELQVNSMQLLYYQAPMSSAMLLVAVPFFEPVFGEGGIFGPWSVSALLMVLLSGVIAFMVNLSIYWIIGNTSPVTYNMFGHFKFCITLFGGYVLFKDPLSINQALGILCTLFGILAYTHFKLSEQEGSRSKLAQRP
What is the function of this protein?
Putative transporter.
What are the official names of this protein?
Solute carrier family 35 member E3, Bladder cancer-overexpressed gene 1 protein.
What is the protein family that this protein belongs to?
Belongs to the TPT transporter family. SLC35E subfamily.
Protein: TDA7_YEASZ
Sequence: MNSNSTIGRTTLGESDTISLSFSEPSSSLNSRSTDVVFASTSTLVPQQGSLTSLPPVSSTATPTYYSTSLTYDETLHTSIDVSSTSTLVSSTDSSSSSEQDTYSSQYDPATSSYSIITPSMSIFSSTSPMSSSSSITSEWSSLTSTTPTLSSSATSLSSSWSSLSSPSSLLVSSSLSLSLSSSYSDTKLFSFDSRSSIFSPSTPTVISPSYTYLSSISATSFQISTTSELSSSWFSTISSPSTTSNKDTTFPSSSRNTSTSFYSSSLSSTNDFSTISKSSKLSPSASSSTVSISTISVPTSSSVSSSSSKVPSNRPSSSSSSDDTTSAYSSTYTFQSLQSTTSSSIPPTTQTPSTSTISTSPIPTSSQVFNTVAISSSEDSKTIYYFYTQTYDITDSSTTFVTGLPTTIAVAKSEVTSFSAPSSTITADMSFYQHWLDGSLDNNKNQGTSKTNTGTIVGSVVGSVGGILICVLVVWFMLVRKRKAKRHFKENDSFCHEIGRRTGFPTTAQAKEASLQAQDSGSQQRNTETASANNPFSNEFNFKARGNPPPVPPPRNVTAMNGSFQNMRSNFMDQENRFSYGSSFTYSSLGSSTQGGFSTLSSNSIRLGRGLDNDISHDERNTVQNNSQGFLREII
What are the official names of this protein?
Topoisomerase I damage affected protein 7.
What is the protein family that this protein belongs to?
Belongs to the TDA7 family.
What are the subcellular locations of this protein?
Vacuole membrane; Single-pass membrane protein.
Protein: LYSY_DEIRA
Sequence: MSTEKKTVAIVGGSGYAGGEFLRLALGHPHLEVTQVTSERSAKLPVSMVHPNLRGATNLKFRKAAELEEADIIVLALPHNSAAKRITEFEAKGKVIVDLSADFRLKDPEVYERFYGEPHPAPEQLGQWVYGNPELHREDLRGATRIACAGCFATSVILALYPLLRLGALAPKDIIATGLVGSSAAGASASESSHHPERAGSLRVYKPVGHRHTAEAQQELPGKFPLHLTAISTPRVRGILTTIQAWVPDGWSDKDVWSAYREVYGQEPFIRIVKVAKGIHRYPDPMLLDGTNFCDIGFEMDVDTGRVVLMSAIDNLVKGTAGHAIQSLNVAQGWDERAGLGFLGLHPT
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of [LysW]-aminoadipate 6-phosphate to yield [LysW]-aminoadipate 6-semialdehyde.
What are the official names of this protein?
[LysW]-L-2-aminoadipate 6-phosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XPT_BACAC
Sequence: MKVLQEKILNEGKVLSGDVLKVDAFLNHQIDPVLMQEIGKEFAKRFKEENITKIVTIESSGIAPAVMAALELGVKVIFARKRKSLTLQDNMYVANVYSFTKQETNEISLSRNHIDESDRVLIIDDFLANGQAALGLMSLVEQAGASIAGIGIVIEKAFQDGGKKLREQGIRVESLAEIASLDNNAVTFVQQETAEVK
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXB_ECOK1
Sequence: MTEQRPLTIALVAGETSGDILGAGLIRALKERVPNARFVGVAGPRMQAEGCEAWYEMEELAVMGIVEVLGRLRRLLHIRADLTKRFGELKPDVFVGIDAPDFNITLEGNLKKQGIKTIHYVSPSVWAWRQKRVFKIGRATDLVLAFLPFEKAFYDKYNVPCRFIGHTMADAMPLDPDKNGARDVLGIPYDAHCLALLPGSRGAEVEMLSADFLKTAQLLRQTYPDLEIVVPLVNAKRREQFERIKAAVAPDLSVHLLDGMGREAMVASDAALLASGTAALECMLAKCPMVVGYRMKPFTFWLAKRLVKTDYVSLPNLLAGRELVKELLQEECEPQKLAAALLPLLANGKTSHAMHDTFRELHQQIRCNADEQAAQAVLELAQ
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: SYDND_THESQ
Sequence: MLRTHTCGELRAADEGKKVKLCGWVDRIRDLGGVRFIDLRDRYGETQIVCDVNSKAYSVVDELTRESVVLVEGTVRKRPEGTENPNIETGEIEVVAERIEILSLADPLPFYPGETPKEEMRLKYRYIDLRSERMKRNIILRYRISKIIRDYFDELGFLEIETPFLTKSTPEGARDFLVPSRLRPGKFYALPQSPQLFKQILMISGFDRYFQIVRCFRDEDLRADRQPEFTQVDVEMSFVDVEDVLNVSEGMVSRVFRESSGIDLKVPFDRIPYDEAMEKYGTDKPDRRYGMELRDFGYAFETTEFKVIRNVLDEGGSVKGFIVPGFASEMSRKKGEELMERMKELGLGGLIWFKLDGGITSPHLKHLEKEFRKIAETENMNEGDVCLIAAHTDRNLLNEALGTLRLEIGKEHFSHLAKGFDVLWVVDFPYFEWSEEEERFVARHHPFTMPVLETLGDDYTKVRAKAYDLVINGYEVGGGSIRIHRRDIQEKIFELLGLSEEEAQKKFGFFLEAFRYGVPPHGGIAFGLDRLVSIIAGESSIREVIAFPKTGNGVCLLTGAPAEVDERQLRELRIRIEEG
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YE0C_SCHPO
Sequence: MSSSTYRKLPKILAAGLAIGCAGGYYAYKNSNKPPGLNPEIYAPFTVNKITELTSDASLFSLVPQSPSEHLTTLEPIAKVTIRDPSMQVQRPYTPLYLDANELKFFIRKYEEGPVSSYIHSKKEGDTIELRGPFKTTKLDCTKYPRIVAIVAGTGIAPIYQLAQSVKSPVDIVYCSRPGQPPLLKEELEKECPNVRVKSVQNRLVNIHDILDWDNVTVPLKDTLCIVCGSQKFVSTIAGPKADYGARQGEVKGLLSNNPFGKVWKL
What are the official names of this protein?
Uncharacterized FAD-binding protein C17H9.12c.
What is the protein family that this protein belongs to?
Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: EIF3I_KLULA
Sequence: MRPIVLKGHERPLTQVKFNRDGDLVFACSKDSVASIWYAINGERLGTLDDHSGTIWSIDVDESTTYALTGGADFCFKIWKVATGVAVHSVSTRSPVLRVEFSPDGSKLLIVLDAVMGHIGSIVVYSLIRNENGEIVNVKEEPDYEITTIEQATKVFVASWSYNGKYIIAGHEDGQISAYYGENGEFVQAKKIHEKSIKDIQFSPDRTYFITSSRDSVASLVDVDTFEVLKTYKADCPLNSASITPLKEFVILGGGQDAKDVTTTSAREGKFEARIYHKVFQDEIGRVKGHFGPLNYVAVSPTGTSYASGGEDGYIRLHHFDKSYFDFKYDVEKTFEVERRQQLQKQE
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit I, eIF3i, Eukaryotic translation initiation factor 3 39 kDa subunit homolog, eIF-3 39 kDa subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit I family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NSUN4_XENTR
Sequence: MAACRGFLLRRINDSCLTFRRHKFKKKWATTLPKIPCSRLALQYFDMNYSMQFGDLWPSIRISLLTEQKYGALVNNFSHKETVLKNLSAFNAKDFISEAQHVISLLQIQNNLDTSEKMTSGEASLNLVGQKNNAEKTQATNLLSSLSNTKLTCFKFSRGDISRFPQSRSDSFGLLEYYLMDAASLLPVLALDVQHGHSVLDLCAAPGGKTLALLQTENCQYLAANDLSTSRSSRLHRVLRSYVPRAQRTEHKVCITSQDGRLWGDAEANTYDRVLVDVPCTTDRHSLLEEENNIFHRIRTKQRQMLPLLQAELLVAGLRAVRPGGEVVYSTCSLSQLQNECVVERAVELAASDHGVHVKPQDLSCFREVFKNTFNFFQGCRVGELVLPHLTANFGPMFFCKLLRIE
What is the function of this protein?
Involved in mitochondrial ribosome large subunit biogenesis.
What are the official names of this protein?
5-methylcytosine rRNA methyltransferase NSUN4, 5-methylcytosine tRNA methyltransferase NSUN4, NOL1/NOP2/Sun domain family member 4.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Mitochondrion.