PharMolix/UniProtQA huggingface dataset:
Protein: NUON_ERWT9
Sequence: MTITPQQLIALLPLLIVGLTVVVVMLSIAWRRNHFVNATLAVVGLNLALFSLYFVGQAGPMDVTPLLRIDAYSMFYTGLVILASLATCTFAYPWLATYPDNREEFYLLVLIAALGGVVLASASHLASLFIGIELISLPLFGLVGYAFQQKRSLEAAIKYTILSAAASSFLLFGMALVYADSGNLGFMALGRSLNDDVIHQPLLLAGLGLMIVGFGFKLSLVPFHLWTPDVYQGAPAPVSTFLATASKIAIFGVLMRLFMYAPMANSEGVRTVLGIIAVASMLFGNLMAISQSNIKRLLGYSSIAHLGYLLVALIAVQSQQLSVETVGVYLAGYLFSSLGAFGVVSLMSSPYRGPDAESLYSYRGLFWHRPILAAVMTVMMLSLAGIPMTLGFIGKFYVIAVGVNAHLWWLTGAVVLGSAIGLYYYLRMTVSLYLSPPELMQRDSPANWAFTAGGVVVLISAILVLVLGIYPQPLISLVNLAQPLH
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TX32_LOXIN
Sequence: MKIELFLVVIFALAIHMATAEEVIESDIEPAERGCIKSGQRCGSPHGLPSNCCDDWKYKGRCGCTMGVCTCGKNCPSRGCDYRTKG
What is the function of this protein?
Toxin active against S. frugiperda larvae.  May act on sodium channels (Nav) (By similarity).
What are the official names of this protein?
U2-sicaritoxin-Li1b, U2-SCRTX-Li1b.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 39 family.
What are the subcellular locations of this protein?
Secreted.
Protein: DXS_NOSS1
Sequence: MHLSEITHPNQLHGLSIRQLQQIARQIRDKHLQTVAEFGGHLGPGLGVVELTLGLYQTLDLDRDKVIWDVGHQAYPHKLITGRYSDFHTLRQKDGIAGYLKRGENKFDHFGAGHASTSISAALGMALARDMNGEKFKAVAVIGDGALTGGMALEAINHAGHLPKTNLLVVLNDNEMSISPNVGAIPRYLNKMRLSPPVQFIKDNFEEQFKHIPFVGESLSPELGRIKEGMKRLAVPKVGAVFEELGFTYMGPVDGHNLEELIATFQQAHQIAGPVLVHVATIKGKGYELAEKDQVGYHAQTPFNLTTGKAIPSNKPKPPAYAKVFSHTLVKLAEQNPKIIGITAAMATGTGLDKLQAKLPNQYIDVGIAEQHAVTLAAGLATEGMRPVAAIYSTFLQRAYDQIIHDVCIQNLPVFFCLDRAGIVGSDGPTHQGMYDIAYLRCIPNIVMMAPKDEAEMQRMVVTGIEHTTGPIAMRFPRGNGYGVPLMEEGWEPLEIGKGEILRNGDDVLIIGYGTMVYPSMQAAEILSEHGIEATVINARFVKPLDTELIVPLAQKIGRVVTLEEGCVMGGFGSAVAEALLDADVVVPVKRIGIPDVLVEHATPDESKAELGLTSRQIAERVLQAYFQKQPSPVS
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: V_MEASC
Sequence: MAEEQARHVKNGLECIRALKAEPIGSLAVEEAMAAWSEISDNPGQDRATCKEEEAGSSGLSKPCLSAIGSTEGGAPRIRGQGSGESDDDAETLGIPSRNLQASSTGLQCYHVYDHSGEAVKGIQDADSIMVQSGLDGDSTLSGGDDESENSDVDIGEPDTEGYAITDRGSAPISMGFRASDVETAEGGEIHELLKLQSRGNNFPKLGKTLNVPPPPNPSRASTSETPIKKGHRREIGLIWNGDRVFIDRWCNPMCSKVTLGTIRARCTCGECPRVCEQCRTDTGVDTRIWYHNLPEIPE
What is the function of this protein?
Plays an essential role in the inhibition of host immune response.  Prevents the establishment of cellular antiviral state by blocking interferon-alpha/beta (IFN-alpha/beta) production and signaling pathway.  Interacts with host IFIH1/MDA5 and DHX58/LGP2 to inhibit the transduction pathway involved in the activation of IFN-beta promoter, thus protecting the virus against cell antiviral state.  Blocks the type I interferon signaling pathway by interacting with host TYK2 and thereby inhibiting downstream STAT1 and STAT2 phosphorylation.  Moderately affects the type II interferon signaling.
What are the official names of this protein?
Non-structural protein V.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses V protein family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: KDGT_CARHZ
Sequence: MKIKATLERVPGGMMVIPLFLGTLINTLFPNAANTFGSFTGALLTGALPILAVFFVCMGATIDFKATPYILKKGGALWITKILIGVIVGVIGAKFLGEGMIKSGPFVGLSVLALVASMNDTNGGLYMALMGQFGKKEDVAAYSVMSLESGPFFTMVTLGVAGLSAFPWQMLVGAILPLIIGMILGNLDKELREFFGRAVPVLIPFFAFGLGAKMNLLDVWKAGLVGILVGVAVVVITGTALFIADRLTGGNGIAGLAAASTAGNAAAVPAVVASANHAYAPVAPAATAIVASSVIVTAFLVPIITAWWAKRIGVVNNNAA
What is the function of this protein?
Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell.
What are the official names of this protein?
2-keto-3-deoxygluconate permease, KDG permease.
What is the protein family that this protein belongs to?
Belongs to the KdgT transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NORV_CITK8
Sequence: MSILVKNNIHWVGQRDWEVRDFHGTEYKTLRGSSYNSYLIREEKNVLIDTVDHKFSREFVQNLRSEIDLADIDYIIINHAEEDHAGALTELMAQIPDTPIYCTANAIDSITGHHHHPEWNFNVVKTGDTLDIGNGKQLIFVETPMLHWPDSMMTYMTGDAVLFSNDAFGQHYCDERLFNDEVDQTELFEQCQRYYANILTPFSRLVTPKITEILGFNLPVDMIATSHGVVWRDNPTQIVELYLKWAADYQEDRITIFYDTMSNNTRMMADAIAQGINEVDPNVAVKIFNVARSDKNEILTNVFRSKGVLVGTSTMNNVMMPKIAGLVEEMTGLRFRNKRASAFGSHGWSGGAVDRLSTRLQDAGFEMSLSLKAKWRPDIDALELCRQHGRDIARQWALAPLPETNVKATTQEEECACAAAAAADLGPSMQCSVCQWIYDPAKGEPLQDVAPGTPWSDVPDNFLCPECSLGKDVFDVLATEAK
What is the function of this protein?
Anaerobic nitric oxide reductase; uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes.  Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified.  NO probably binds to the di-iron center; electrons enter from the NorW at rubredoxin and are transferred sequentially to the FMN center and the di-iron center.  Also able to function as an aerobic oxygen reductase.
What are the official names of this protein?
Anaerobic nitric oxide reductase flavorubredoxin, FlRd, FlavoRb.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STU1_KLULA
Sequence: MSDEFNGLDGLSDELLSAERKLDILTQFKAHVKKTLVNEQVCVKYFENLSRLLVERGSNRRRGNDGDDVVFALAHSALCYLIKRVAMQAQHKFQHDLIELIVSTLFSIPFADKKVWQSSVKALEAIYLAKPNEFCQVLNESIAYNGSIRTNVLLLIDELARMESSNGRNGSMFLQKFIPFWVQEMNTNDSISNTDIELIYDIVANRCPEPMVRSMVDSVIRESAAKVFKSRLVGKLNNHGSESDMKDDFDRSITHTNSINSQVFNLQNELQSIMHQAPQFPTVPAPEPISYSNLSYLIKDLESMLPAFEGSRETEQNWKIRQTNVTKLRSIVLGNVSIEFPDKFLELWKDLNLQYCVTKSALSLRTSLCTHGCSLVKDLCCVFNSMLDISIIENLWSCLAKLMSNTKKIANQNAFICLITLLSTVPFHSRLFNHCFALIRDKNNVSRLYSSTFLRILIVRFHKRLISQHHVYVEEWLQKGLTDAQTTIRESMRITFWYWFKVSPMSGKKMLNLFQPQIKRALENSIPTHLDINYEAAIPPQSKESSRRSSLLPKRFPSYAAPTQSSHLPRSSIKRSLTDLAQGTQSFSKRSLRTPPDHDMNIDLTSELTNSQTNPLLNRYMKREEVEPEPLHVILSKDPKLGLDLLQKYLLSDTKIGDEEKVQSAIVSLIRTNPKAFKPLLHLPKFYQLIPLNFSMVLLPLNDLDISMIETQFKTYDIINNVISILQSLEDKNSEWSIFYVRFKYQIYNFCFNTIAKMLNTVTLSDQLINELINACGKDMDAEKYYKLILNIYLADKTKFVRLLKSTSTASTKLKIANVIQKKDSEFKIKSILNYPSVPEPIVSPEEHHLLEMTMVNPLGKRTVSSNTVIHNSLEGLDESESNPNIIADEDNHSEKEDLVTVPPVAKNSVNTVSFVADSPSDSDNDDTKKNGSDVVDHEEIRDHEESHGFTKFGGFSKLTEMTKVHSVFQPETVDENVDPMEVDSPDESNLDQKSLLTDIFLKNQHQEGSVSPIFKPQELNNDPRHDYDSDMLSDAINGIEIKTNDGSVANRSEDDIKTLGTNMGSVSDPKTFKPINLAHFANDSLFSFELKFIDASIGIVNLTQLKLIVQSIINNGTFKMNELQYILKCFLCYDQEVLEWIHDQHELKDVWAITELLLSSSSSESQIPTNIAYKSIILTACLLTIDDELEHTVLKDSSISQLFEHIISLVAKLDTFENEIYFACTELRTLLLSQDNNKHLPSFLEKCLKALCDTKEQYIVKISFLLETINGIISSMGNLLSVDVLRDLAKTISRYTPSDVAEWRFASCTALATIYSQLISRSTPVGYIRSLMPLLDPSDFEVVRSLSTTKDATRRLG
What is the function of this protein?
Microtubule binding protein that promotes the stabilization of dynamic microtubules.  Required for mitotic spindle formation (By similarity).
What are the official names of this protein?
Protein STU1.
What is the protein family that this protein belongs to?
Belongs to the CLASP family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Nucleus. Cytoplasm, cytoskeleton, spindle.
Protein: HTPX_AERS4
Sequence: MKRIMLFLVTNLAVMLVLGVVLNILFSVLGINKSSISGLLMFCAVFGFGGSFISLLMSKWMAKRSYGVQVIEQPRNETEHWLVSTVARQAREAGIKMPEVGIYDSPEMNAFATGARRDDSLVAVSSGLLYSMSRDEAEAVLAHEVSHVANGDMVTLTLIQGVVNTFVMFFARIVAGVISNFFSSNNDEESSSSGGFAYMITVFVLEMAFGVLASMIVMWFSRQREFRADAGAAKLAGRDKMIAALQRLSRGAEPQMEGSMMAFGINGKRSMSELFMSHPPIEQRIAALRG
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NPRL3_HUMAN
Sequence: MRDNTSPISVILVSSGSRGNKLLFRYPFQRSQEHPASQTSKPRSRYAASNTGDHADEQDGDSRFSDVILATILATKSEMCGQKFELKIDNVRFVGHPTLLQHALGQISKTDPSPKREAPTMILFNVVFALRANADPSVINCLHNLSRRIATVLQHEERRCQYLTREAKLILALQDEVSAMADGNEGPQSPFHHILPKCKLARDLKEAYDSLCTSGVVRLHINSWLEVSFCLPHKIHYAASSLIPPEAIERSLKAIRPYHALLLLSDEKSLLGELPIDCSPALVRVIKTTSAVKNLQQLAQDADLALLQVFQLAAHLVYWGKAIIIYPLCENNVYMLSPNASVCLYSPLAEQFSHQFPSHDLPSVLAKFSLPVSLSEFRNPLAPAVQETQLIQMVVWMLQRRLLIQLHTYVCLMASPSEEEPRPREDDVPFTARVGGRSLSTPNALSFGSPTSSDDMTLTSPSMDNSSAELLPSGDSPLNQRMTENLLASLSEHERAAILSVPAAQNPEDLRMFARLLHYFRGRHHLEEIMYNENTRRSQLLMLFDKFRSVLVVTTHEDPVIAVFQALLP
What is the function of this protein?
As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway.  The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling.  The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway.
What are the official names of this protein?
GATOR complex protein NPRL3, -14 gene protein, Alpha-globin regulatory element-containing gene protein, Nitrogen permease regulator 3-like protein, Protein CGTHBA.
What is the protein family that this protein belongs to?
Belongs to the NPR3 family.
What are the subcellular locations of this protein?
Lysosome membrane. Note=Localization to lysosomes is amino acid-independent.
Protein: CRCB2_NATPD
Sequence: MALLTALAVGAGGAAGAVARYAVGLSVGRRAVDTGLVNVFGSLLFGVAIGADFGGAPAVAVTVGFCGAFTTFSSFAVETVRLAEDGQRLAAAGNAVGTLAAALLAVFLGIALGAAL
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 2.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: APGM_METLZ
Sequence: MTASKILLLIIDGVGDRPCGVLGNKTPLQAAKIPNLDRLATEGICGIMDPIAPGVRGGSDTSHLSLLGYDPHIYYTGRGPLEAAGCGIKMEPGMIGFRANYATIDDDGNVIDRRAGRIPDTTEITAAVKNGVDLSKYGVEIEFSPGTGHRAALALKGKGLSAAVSSNDPKKTGVQPKTIHPDDDSKEAAFTAEVCNEFSRQAAEILKNHPVNLERKARGEFPANVVLIRGAGEMGVYETFEEKHELSGSVVAAAALIAGIGSSVGLERIPVLPTTPLDEQVRLVCRELEKKDFVLFNVKTADEYGHDGKAVEKTKYLEEVDAALLPFFDMPELMIAVCGDHSTPCTIKEHSADPVPLILHGDGTRIDLVTNYDEISCAAGGLCRISGGSLMPILLDLIDKTHKYGA
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, aPGAM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
Protein: HPRK_PARXL
Sequence: MDTSSINAQSIFDDNAATLKLSWLTGHEGWERGFSSESVANATSSADLVGHLNLIHPNRIQVLGDAEIDYYKRQTDEDRSRHMAELIALEPPFLVVAGGVPAPPELVLRCTRSSTPLFTTPMSAAAVIDSLRLYMSRILAPRATLHGVFLDILGMGVLLTGDSGLGKSELGLELISRGHGLVADDAVDFVRLGPDFVEGRCPPLLQNLLEVRGLGLLDIKTIFGETAVRRKMKLKLIVQLVRRPDGEFQRLPLESQTVDVLGLPISKVTIQVAAGRNLAVLVEAAVRNTILQLRGIDTLRDFMDRQRLAMQDPDSQFPGKLI
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: HIS6_ECOSE
Sequence: MLAKRIIPCLDVRDGQVVKGVQFRNHEIIGDIVPLAKRYAEEGADELVFYDITASSDGRVVDKSWVSRVAEVIDIPFCVAGGIKSLDDAAKILSFGADKISINSPALADPTLITRLADRFGVQCIVVGIDTWYDGETGKYHVNQYTGDESRTRVTQWETLDWVQEVQKRGAGEIVLNMMNQDGVRNGYDLEQLKKVREVCHVPLIASGGAGTMEHFLEAFRDADVDGALAASVFHKQIINIGELKAYLATQGVEIRIC
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHMT_MYCBO
Sequence: MAFSRTHSLLARAGSTSTYKRVWRYWYPLMTRGLGNDEIVFINWAYEEDPPMDLPLEASDEPNRAHINLYHRTATQVDLGGKQVLEVSCGHGGGASYLTRTLHPASYTGLDLNQAGIKLCKKRHRLPGLDFVRGDAENLPFDDESFDVVLNVEASHCYPHFRRFLAEVVRVLRPGGYFPYADLRPNNEIAAWEADLAATPLRQLSQRQINAEVLRGIGNNSQKSRDLVDRHLPAFLRFAGREFIGVQGTQLSRYLEGGELSYRMYCFTKD
What is the function of this protein?
Catalyzes the methylation of the lipid moiety of the intermediate compounds phthiotriol and glycosylated phenolphthiotriol dimycoserosates to form phthiocerol dimycocerosates (DIM A) and glycosylated phenolphthiocerol dimycocerosates (PGL).
What are the official names of this protein?
Phthiotriol/phenolphthiotriol dimycocerosates methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Phthiotriol/phenolphthiotriol dimycocerosates methyltransferase family.
Protein: RPOA_ALKMQ
Sequence: MIEMEKPKVEVFEISDDSTYGKFVVEPLERGYGTTLGNSLRRIMLSSLPGAAVTSVKIEGILHEFSTIPGVKEDVTEIILNLKDLSIGIDGNEPKTLRIEMEGPGTVTAGDIIADADVEVLNPDMYIATLDDNSKLNMEINIAKGRGYVSAENNKTAGMPIGVIPVDSIFTPVRKVSYFVGNTRVGQVTDYDKLEIEVFTDGSIKPDEAISLAAKVMSEHLNLFITLKEDVSDVEIMVQKEEDKKEKVLEMTIEELDLSVRSYNCLKRAGINTVEELSLKSEEDMMKVRNLGKKSLEEVDKKLEELGLGLRPSDE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: FRDC_SHIDS
Sequence: MTTKRKPYVRPMTSTWWKKLPFYRFYMLREGTAVPAVWFSIELIFGLFALKNGPEAWAGFVDFLQNPVIVIINLITLAAALLHTKTWFELAPKAANIIVKDEKIGPEPIIKSLWAVTVVATIVILFVALYW
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit C, Fumarate reductase 15 kDa hydrophobic protein, Quinol-fumarate reductase subunit C, QFR subunit C.
What is the protein family that this protein belongs to?
Belongs to the FrdC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRMA_WOLSU
Sequence: MICPHQGTCGGCALALPYEEQWKLKESEFRELLPLSKDTPTDLYPSAPHSFRARAEFRLYRNESGRLSYAMSQKGSKQPLPIQSCPILLPSIQALMPSLLEALESDEILTQKLFGVEFLSGLSQEVLVSLLYHKRLDHAWEERALGLLSSLPTLSSLIGRSKGQKIVLGESFITETLTIDSKPWRFLHYEGSFTQPNPKVNEKMIEWIISAPPQGDLLELYCGAGNFTLPLSSRYAKILATEVSKTSIHAAKQNCELNSVRHISFVRLNAQETQSALEGEREFYRLRELDLPSYDFQAVFVDPPRAGLGAEVASFLRRFDQILYISCNPKTLQSDLEVLQLSHDVERFALFDQFPYTPHLESGVILRQRR
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: IMPA2_ARATH
Sequence: MSLRPNAKTEVRRNRYKVAVDAEEGRRRREDNMVEIRKSKREESLQKKRREGLQANQLPQFAPSPVPASSTVEKKLESLPAMVGGVWSDDRSLQLEATTQFRKLLSIERSPPIEEVIDAGVVPRFVEFLTREDYPQLQFEAAWALTNIASGTSENTKVVIEHGAVPIFVQLLASQSDDVREQAVWALGNVAGDSPRCRDLVLGQGALIPLLSQLNEHAKLSMLRNATWTLSNFCRGKPQPPFDQVRPALPALERLIHSTDEEVLTDACWALSYLSDGTNDKIQSVIEAGVVPRLVELLQHQSPSVLIPALRSIGNIVTGDDLQTQCVISHGALLSLLSLLTHNHKKSIKKEACWTISNITAGNRDQIQAVCEAGLICPLVNLLQNAEFDIKKEAAWAISNATSGGSPDQIKYMVEQGVVKPLCDLLVCPDPRIITVCLEGLENILKVGEAEKVTGNTGDVNFYAQLIDDAEGLEKIENLQSHDNSEIYEKAVKILETYWLEEEDETLPPGDPSAQGFQFGGGNDAAVPPGGFNFQ
What is the function of this protein?
Binds to conventional NLS motifs and mediates nuclear protein import across the nuclear envelope (By similarity).  Acts as cellular receptor for the nuclear import of the virD2 protein of Agrobacterium, but is not essential for Agrobacterium-mediated root transformation (PubMed:18836040).
What are the official names of this protein?
Importin subunit alpha-2, IMPa-2.
What is the protein family that this protein belongs to?
Belongs to the importin alpha family.
What are the subcellular locations of this protein?
Nucleus envelope.
Protein: UVRC_CORGB
Sequence: MADPTTYRPAPGTIPTEPGVYKFRDENRRVIYVGKAKNLRSRLSNYFQDVTQLHPRTRQMVFAASSVEWTVVSSEVEALQLEYTWIKRFDPRFNVKYRDDKTYPMLAVSTGERFPRAFFFRGPRRKGVRYFGPYSHAWAVRETLDLLTRVFPMRTCSKGVFNRHESLGRPCLLGYIDKCAAPCVGRVSEEEHREIVDGFTSFMAGHTDKVTRKLNADMMAAAEELDFERAARLRDDLEAIDKVMEKQAVVLGDGTDADIIAFATDQLEAAVQVFNIRGGRIRGQRGWVVDKPGDYAGLLVDATTQPEGDAPETDPALPFLMQDFLVQFYGDAVERAETEAKEDAAVIERRGVDKHSFEEAAPVTRASVVPREILVQVAPNEAEQTLKVLEELRGAGVDARVPQRGDKRALMETVERNAKELLKQHKLKRVGDLTARSAALQELQEALDMEQAPLRIECTDISHIQGTDVVASLVVFEDGLPRKSDYRRYRVKEAAGDGHSNDVASIAEITRRRFLRHNQDKLAVPEAEEFDGSTFSDEKVEEMSTDARRFAYPPQIFIVDGGAPQVAAAQEVFDELGIVDVVLIGLAKRLEEIWLPGDPDPVILPRNSQALFLLQQIRDEAHRFAITYHRQQRSKRMRVSELDSIKGLGQSRRTELVKHFGSVAKLKEASVEDISQVKGFGPKLAEAVYEGLHASK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_STUS1
Sequence: MLDSKLVRTQLQDVAARLATRGYQLDVARIEALEAQRKTVQTRTEQLQAERNARSKSIGQAKQRGEDIAPLLADVDRMGSELESGKQELDRIQSELDQLMLSIPNLPHDSVPVGADEEENVEVRRWGTPKAFDFPVQDHVALGEQHGWLDFETAAKLSGARFALMRGPIARLHRALAQFMIDLHTREHGYEEAYTPYLVQAPALQGTGQLPKFEDDLFKISREGEADFYLIPTAEVSLTNIVAGEILDAKQLPLKFVAHTPCFRSEAGASGRDTRGMIRQHQFDKVEMVQIVEPSKSFEALEELTGNAEKVLQLLELPYRVLSLCTGDMGFGATKTYDLEVWVPSQDKYREISSCSNCGDFQARRMQARYRNPETGKPELVHTLNGSGLAVGRTLVAVLENYQQADGRILVPEVLKPYMGGIEVIG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
Protein: CENPL_MOUSE
Sequence: MDSCDFRGLTSRRRTSNLKNYFVGATPLQKRLELVRRQNSDFPSPSRRKIPQCSQLQEDIDPQKVAFLLHKQWTIYSLTPLYKFSYSNLKDYSRLLSAFIVAEKQKGVAVEVGEDFNIKVIFSTLLGVKGTQRDHEAFLVQILSKSQSSREHREDKVLWTGWFCCVFGESLQETVSEDFTCLPLFLANGAESNTSLIRDWFQKTFDCCFSPLAISAFNLSWMAAMWTACKMDRYMATTEFLWSVPCSPQSLDISYAIHPEDAKALWESVHKTPGEVTQEEVDLFMNCLYSHFHRHFKIHLAATRLVRVSTSVASAHTDGKIKVSLNRSN
What is the function of this protein?
Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation.  May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex (By similarity).
What are the official names of this protein?
Centromere protein L, CENP-L.
What is the protein family that this protein belongs to?
Belongs to the CENP-L/IML3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Note=Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex (By similarity).
Protein: CARA_BRUC2
Sequence: MTETTPKTAPWTVQKRTAVLVLADGTVIEGKGLGATGAVEAEVVFNTALTGYEEILTDPSYAGQIVTFTFPHIGNVGANAEDIEDLTPANRHGAVGAIFKADITAPSNFRAAEDLDSWLKHRGIIALAGIDTRALTALIRERGAQNAVIAHDPNGNFDLDALKARAANWCGLENLDLAKDVTIGQSLVWKELPWTLQDGYGEQDAPQYHVVALDFGVKRNILRLLTGLGAKVTVLPATATAEDVLAHNPDGVFLSNGPGDPAATGEYAVPTIGKLVETGIPLFGICLGHQMLALALGGRTEKMHQGHHGANHPVKDYTTGKVEIVSMNHGFAVDSDSLPENVEETHVSLFDGTNCGLRVVGKPVFSVQHHPEASPGPQDSHYLFRRFINLIRERKGQAPLPEREQAA
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.