PharMolix/UniProtQA huggingface dataset:
Protein: ATX9_TETTH
Sequence: MRVSSIEAEMENPIDVDKTDVEGELKIKQVTLLRENIVKKIVFFLVAIFCSDRPSVLKKVFYEEVSKQEEATHVYVLASDLTDYIEEASLKENPEEGGEKSIYFVNRLQKYIYHKKQNKFRAIEYFIQGKSYSEIANNKPLATGRVDQLLAYYGKSEIEINVPSFLTLMWREFKKPINFLLYFGIIVWGIEQMYVSTAITVVFTTTINSLICIYIRGVMQKLKDACLNNTSVIVQRHNGQGYQEITVASNMIAPGDIVLFKREVTLPFDCVILEGSCQVTEANITGENVAIGKCQIPTDHHNDIFKYESSKSHTLFQGTQLMKIEDDILKVIVVRTGFGSYKGQIIRALLYPKPFNKKFQQQAVKLTILMATLLLIGFLSTLSRLLDIELPPLFIAFRFLDILIYSAPPGMPMLIAITNFVGLKRLKNNQILGQDPNSASQAGRIQTLCFDKTGTLTEDKVDLIGYQLKGQNQTFDKIQCQDPNNISIEHKLFSICHEVTKINNKLLGDLMDVKMAEFSTLDIDYDHEAKQHYSKSGNKRFYCIQVNQFHSEYQSMSVVCKEVDMITKEFKHYFFIKGSPEKIQSLSHVQSSEKAQLSTLINEGYRILGFGYKEIPQSEIDAFLDLSREQQEANVQSLGFLIYKNNLKPDTQEVIKEFKEACYNIKVISGDNPITTLKISQELEIVNRKNPTVIINFEETENVKSHLIITEIQPDNSTQVIDFSSAQNEQDYINKQMSYCCDAFLNNKSFCFSGKAHYYFQLKAKTDHISFKPEWVKMQDKSVQKIISFYQMLIINTNVFARTQPEQKQTIVRLLKESDQIVCMVGDGANDCSAIREADVGISFAEADGQFSSSYVSLSTSLSCVKRVLLEGRVNLSNSVEIFKGYLQVALLRYLGFLTLAYFYSSYSSGQMDWQALASGYFLVYLILGCNTPLKKLEKSVFDDNLFSIYNVTSVLFGFTLHILSIVGCVESLHASPIYKEVNSLDAENNFQFETQHNTVLNFNILINFFYVIISNHIGKPMKDRYYKNTIAIYYDLGLIYTCKCMILQVLLILEHTHHGLIFLILLLDQEFSSSLTVQVYFSLPMNLFLPEEFSLNFTQEVKKEKELLICNSSSTILEVDYNLRLNYFQQNF
What are the official names of this protein?
Probable cation-transporting ATPase 9.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NADA_LISIN
Sequence: MNLLEKVEQDTMPARYKHMTSQEMIARVTEIKAQLGEDLFIPCHHYQKDEVVPFADAIGDSLQLAQIAANNKKAKHIVFCGVHFMAETADMLTTNEQIVTLPDMRAGCSMADMADIHQLTNAWPKLQHLFGDTILPVTYINSTAAIKSFVGEHGGTTVTSSNATKIVSWALQQKERIFFLPDQHLGRNTAFELGIPLEHMAIWNPIKNELEYDGNLDDCKVILWKGYCSVHQHFTVKNIENIRKNHPNMRIIVHPECTHEVVSLADDSGSTKKIVTEISNAAPGTEWAVGTEANLVGRIIQENPDKKIVSLNPFMCPCMTMNRIDLPHLLWTLEAIQNGEQRNQIKVDEHTTKFALKALERMLQLS
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPF_SHEPC
Sequence: MIQFTKMHGLGNDFMVVDGVTQNVFFSPEQIRRLADRNFGIGFDQLLLVEPPYDPDLDFHYRIFNADGSEVEQCGNGARCFARFVRNKGLTNKNKIRVSTSSGKMTLRLERDGTVTVNMGVPILEPSLIPFKAKKPEKTYLLQTAQQTFLCGAASMGNPHCVLDVEDVASAAVAEIGALLTKHERFPRGVNVGFMQVINSGHIKLRVYERGAAETLACGTGACAAVVVGQIQGKLDQQVRVDLPGGTLTINWEGEGKPLWMTGPAQHVYDGQIQL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y211_AQUAE
Sequence: MLSEETIRVIKSTVPLLKEHGTEITARMYELLFSKYPKTKELFAGASEEQPKKLANAIIAYATYIDRLEELDNAISTIARSHVRRNVKPEHYPLVKECLLQAIEEVLNPGEEVLKAWEEAYDFLAKTLITLEKKLYSQP
What are the official names of this protein?
Uncharacterized globin-like protein aq_211.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: PTN1_MOUSE
Sequence: MEMEKEFEEIDKAGNWAAIYQDIRHEASDFPCKVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRIMEKGSLKCAQYWPQQEEKEMVFDDTGLKLTLISEDVKSYYTVRQLELENLTTKETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSLEHGPIVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRRFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSREDLDLPPEHVPPPPRPPKRTLEPHNGKCKELFSSHQWVSEETCGDEDSLAREEGRAQSSAMHSVSSMSPDTEVRRRMVGGGLQSAQASVPTEEELSSTEEEHKAHWPSHWKPFLVNVCMATLLATGAYLCYRVCFH
What is the function of this protein?
Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response.  Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK.  May play an important role in CKII- and p60c-src-induced signal transduction cascades.  May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion.  May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET (By similarity).
What are the official names of this protein?
Tyrosine-protein phosphatase non-receptor type 1, Protein-tyrosine phosphatase 1B, PTP-1B, Protein-tyrosine phosphatase HA2, PTP-HA2.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=Interacts with EPHA3 at the cell membrane.
Protein: VP3_EUMPO
Sequence: MRFTFVLVIAATVAVLGFFGINAEPMPDPHAEPYPDAAINPKSVQSLLG
What are the official names of this protein?
Venom peptide 3, EpVP3, VP3.
What are the subcellular locations of this protein?
Secreted.
Protein: ENO_EHRRG
Sequence: MANVKINNISARQILDSRGYPTIEVQITLSNNVFAKASIPSGASVGKFEAVELRDHDTNYYHGYGVTKAVNLINSEIGQKIIKLETLDQEKIDNALIEIDGTNNKSRVGANSILAISLAVAKAAASTLNIPLYQYLGGITAKILPTPLINIINGGMHADNNLDFHEFMIIPHGANSFEDAIRMSSEVFHTLKKILKQKQYNTNVGDEGGFAPNIKDNTEVFDIIIDAIEKSGYKVYKDFSLGLDVAASTFYKNEKYKFSDYQFSTHELVEYYKNIVTQYPIISLEDPIAEEDTLGWKMITKELGDKIQIVGDDLFVTNCKLIKNGIDNNMANAVLIKPNQIGTLTETLNAIRLAQKNNYKVILSHRSGETNDTTISHIAVAVNCGQIKTGSLSRSERLAKYNELLYIEKLLNTSAIYQGML
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RNFD_SHEFN
Sequence: MAFKIASSPHVSTTLHTNTVMKRVALCLIPGIAVQSYYFGYGTLVQLLLAITVAYLAEAAVMKLRNRNITATLTDNSALVTASLLAVAIPPLAPWWLIVIGTLFAIVIVKQLYGGLGNNVFNPAMAAYVLLLISFPVQMTSWVAPQTLTVNYADMLHTFNSIFQLNAGYAADFFHLAIDGTTMATPLDTLKTDLSMGLTTTESMTKTIFSGSVGEGWFWVNMAYLVGGLVMLKLKVIRWHISGAIVLTLFVCASIGFLISPDTFVSPIMHLFSGGTMLAAFFIATDPVTAATSPRGRLIFGAMIGLLIYLIRTFGGYPDAVAFAVLLANMCAPFIDYYVRPRSYGHRVGN
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit D, Rnf electron transport complex subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MDHC_TAESO
Sequence: MPGPLRVLITGAAGQIAYNLSNMVANGNLFGKDQKIILHLLDIPEAKTVLEGVVMELQDCAFTVLEGIVPTHCLKEAFTDIDVALMVGAMPRKQGMERRDLLSSNVKIFKDQGEALEKYAKKTVKVLVVGNPANTNCLIMSKYAPSIPKENFTALSRLDHNRAIYQVAAKVGVPSECVKNVCIWGNHSNKQFPDLAHAVVTKGGKQHPAKELINDEKWVKEVFTPCVQNRGAAVIGLRKLSSAASAAKAIVDQMHDWWFGTKEGEWVSMSVYSTGEHYGAPKDIYFSFPVTIKNGHYKVVDGLAMDEWGKGLFKITADELVDEREVALSSFK
What is the function of this protein?
Malate dehydrogenase.  Has no activity with NADPH as substrate.  Does not show lactate dehydrogenase activity.
What are the official names of this protein?
Malate dehydrogenase, cytoplasmic, Cytosolic malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBX7_SCHPO
Sequence: MKMLQNKGPLQELTLNAMAPNGIFQDEPMIQKFENHYVFKKDMKSKRNKEVKNQMNDWLAYGYLCSVHEAKKWLEEETNNEYQNLDDFVDALVNGKVLCQLAFKYYPKLASNWKPRYQISERNTVYLNAFFHFLDFIGMFTPFRFETKDLVRRFNIPKVIYCLHALSYLLDFLEVTRHVPSLYGKLRIKKSQLNTATKEISLLKKAKKFPNFPKLKNFFCSYSHRHETATSNKQVSCFREVPAWIKQCQSQCRGFLTRKCVSIEKLRRDDMSERLGWLPKLETKLSSISDEERLILLKESHQIYRKMVSLHLELLHLPQLEMSLDFCGFSSDDSSIAISSQLVPPILNNLIFKLEESPQIWILIISRFSSDGIDKIDVQNFILLILKFFGFAISASDRRSFLNLIMSCVMVSIQQSSAEVGHSTSDSLISWASRLFTKGFCLQLQSFFEKHLGNVVDKFFLEHLCETTIESDAMRVVTEMLVSCYENRERIPNELPMVLKQIYYSRSESFKPSAIKEFIEYFLCDQLMNCLSVYYSKYFEGKDSKKFTLVKHFMNSLFGRVKLNEQTEIIWHTRNYRIVEALVRKLIHLSTPKIIPVYGGRTLSCTHKDIFDLQNILRYCDERGDFSSFPSFKKLISLLGSPKLFKKHENQILLLESKNEVIHSSLPCSKSSLYQLSLSLCIPLIEGHLRNSLEEILFGVPTELENQKFMSVLRNDKLIKSIHPGSLSGISNSFVNSKHPIEQWQSRLRKILHLFSGRNEDIASLQCVLQFGSSERIHLEDIQNSHRYLCSLKKNNSQKDIHRNPLLSHVFDTNTKSFDTLKTLNYKHAILKKSMGELYKMEMIHECPRQLFGQILVVYLNRERTLLNFYLIENSKTIDEATLQLTDLIQAIKTGIYYLRMFNLPFHVKQLYTWLAPISKYDSEISFNQKKERRKTFLSFERRGKNRKF
What are the official names of this protein?
Uncharacterized protein C17D1.07c.
What are the subcellular locations of this protein?
Nucleus.
Protein: YAFD_ECO45
Sequence: MRKNTYAMRYVAGQPAERILPPGSFASIGQALPPGEPLSTEERIRILVWNIYKQQRAEWLSVLKNYGKDAHLVLLQEAQTTPELVQFATANYLAADQVPAFVLPQHPSGVMTLSAAHPVYCCPLREREPILRLAKSALVTVYPLPDTRLLMVVNIHAVNFSLGVDVYSKQLLPIGDQIAHHSGPVIMAGDFNAWSRRRMNALYRFAREMSLRQVRFTDDQRRRAFGRPLDFVFYRGLNVSEASVLVTRASDHNPLLVEFSPGKPDK
What are the official names of this protein?
UPF0294 protein YafD.
What is the protein family that this protein belongs to?
Belongs to the UPF0294 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_GEOUR
Sequence: MELNSLKPAAGASKNRKRIGRGTGSGHGKTATKGHKGQKARSGGSIKAGFEGGQMPMHRRLPKRGFTPLAKKIYSVVNLSQLDVFETGSCVDIEAMQKSGLVKNVCDGIKILATGELTKALTVKAHKFSATARNKITSVGGTVEEI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: EA47_LAMBD
Sequence: MTKKPWERRLKDLSHLLKCCIDTYFDPELFRLNLNQFLQTARTVTFIIQKNKNQIIGYDIWYNNNVIEKWKNDPLMAWAKNSRNTIEKQGDLEMYSEAKATLISSYIEENDIEFITNESMLNIGIKKLVRLAQKKLPSYLTESSIIKSERRWVANTLKDYELLHALAIIYGRMYNCCNSLGIQINNPMGDDVISPTSFDSLFDEARRITYLKLKDYSISKLSFSMIQYDNKIIPEDIKERLKLVDKPKNITSTEELVDYTAKLAETTFLKDGYHIQTLIFYDKQFHPIDLINTTFEDQADKYIFWRYAADRAKITNAYGFIWISELWLRKASIYSNKPIHTMPIIDERLQVIGIDSNNNQKCISWKIVRENEEKKPTLEISTADSKHDEKPYFMRSVLKAIGGDVNTMNN
What are the official names of this protein?
Protein ea47.
Protein: H32_ORYSI
Sequence: MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRFRPGTVALREIRKYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVAALQEAAEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.2.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: DNJA1_BOVIN
Sequence: MVKETTYYDVLGVKPNATQEELKKAYRKLALKYHPDKNPNEGEKFKQISQAYEVLSDAKKRELYDKGGEQAIKEGGAGGGFGSPMDIFDMFFGGGGRMQRERRGKNVVHQLTVTLEDLYNGATRKLALQKNVICDKCEGRGGKKGAVECCPNCRGTGMQIRIHQIGPGMVQQIQSVCMECQGHGERISPKDRCKSCNGRKIVREKKILEVHIDKGMKDGQKITFHGEGDQEPGLEPGDIIIVLDQKDHAVFTRRGEDLFMCMDIQLVEALCGFQKPISTLDNRTIVITSHPGQIVKHGDIKCVLNEGMPIYRRPYEKGRLIIEFKVNFPENGFLSPDKLSLLEKLLPERKEVEETDEMDQVELVDFDPNQERRRHYNGEAYEDDEHHPRGGVQCQTS
What is the function of this protein?
Co-chaperone for HSPA8/Hsc70.  Plays a role in protein transport into mitochondria via its role as co-chaperone.  Functions as co-chaperone for HSPA1B and negatively regulates the translocation of BAX from the cytosol to mitochondria in response to cellular stress, thereby protecting cells against apoptosis.  Stimulates ATP hydrolysis, but not the folding of unfolded proteins mediated by HSPA1A (in vitro).  Promotes apoptosis in response to cellular stress mediated by exposure to anisomycin or UV (By similarity).
What are the official names of this protein?
DnaJ homolog subfamily A member 1.
What are the subcellular locations of this protein?
Membrane; Lipid-anchor. Cytoplasm. Microsome. Mitochondrion. Nucleus. Cytoplasm, perinuclear region. Note=Primarily cytoplasmic and associated with microsomes. A minor proportion is associated with nuclei and mitochondria (By similarity).
Protein: KCND1_MOUSE
Sequence: MAAGVATWLPFARAAAVGWLPLAQQPLPPAPEVKASRGDEVLVVNVSGRRFETWKNTLDRYPDTLLGSSEKEFFYDAESGEYFFDRDPDMFRHVLNFYRTGRLHCPRQECIQAFDEELAFYGLVPELVGDCCLEEYRDRKKENAERLAEDEEAEQAGEGPALPAGSSLRQRLWRAFENPHTSTAALVFYYVTGFFIAVSVIANVVETIPCRGTPRWPSKEQSCGDRFPTAFFCMDTACVLIFTGEYLLRLFAAPSRCRFLRSVMSLIDVVAILPYYIGLFVPKNDDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGTSKTNFTSIPAAFWYTIVTMTTLGYGDMVPSTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQQKVRLARIRLAKSGTTNAFLQYKQNGGLEDSGSGDGQMLCVRSRSAFEQQHHHLLHCLEKTTCHEFTDELTFSEALGAVSLGGRTSRSTSVSSQPMGPGSLFSSCCSRRVNRRAIRLANSTASVSRGSMQELDTLAGLRRSPAPQTRSSLNAKPHDSLDLNCDSRDFVAAIISIPTPPANTPDESQPSSPSGGGGSGGTPNTTLRNSSLGTPCLLPETVKISSL
What is the function of this protein?
Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels.  May contribute to I(To) current in the heart and I(Sa) current in neurons.  Channel properties are modulated by subunit assembly.
What are the official names of this protein?
Potassium voltage-gated channel subfamily D member 1, Voltage-gated potassium channel subunit Kv4.1, mShal.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. D (Shal) (TC 1.A.1.2) subfamily. Kv4.1/KCND1 sub-subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell projection, dendrite.
Protein: NQRF_NEIG1
Sequence: MEIILGIVMFTVIVLALALMILFAKSKLVSEGDITIKVNDEKELTMPAGGKLLGALASQGIFVPSACGGGGSCGQCRVVVKSGGGDILPTELSHISKREAREGCRLSCQVNVKTDMDIEVPEEVFGVKKWECTVISNDNKATFIKELKLAIPEGEEVPFRAGGYIQIEAPPHTVAYKDFDIPKEYHEDWDKYNLWQYVSKVNEPILRAYSMASYPEEKGIIMLNVRIATPPPRVPNAPPGQMSSYIWSLKPGDKVTISGPFGEFFAKDTDAEMVFIGGGAGMAPMRSHIFDQLKRLHSKRKITFWYGARSKREMFYVEDFDQLAAEFPNFTWHVALSDPLPEDNWDGYTGFIHNVVYENHLKNHEAPEDCEFYMCGPPIMNQSVIKMLKDLGVEDENILLDDFGG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit F, Na(+)-NQR subunit F, Na(+)-translocating NQR subunit F, NQR complex subunit F, NQR-1 subunit F.
What is the protein family that this protein belongs to?
Belongs to the NqrF family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: CYSH_STAEQ
Sequence: MSIERITYDNFQNDPFINELDINDETKGAYEILKWAYQTYENDIVYSCSFGAESMVLIDLISQIKPDAQIVFLDTDLHFQETYDLIDRVKDKYPQLRIKMKKPELTLEEQGEKYNPALWKNDPNQCCYIRKIKPLEDVLSGAVAWISGLRRAQSPTRAHTNFINKDERFKSIKVCPLIYWTEEEVWSYIRDKDLPYNELHDQNYPSIGCIPCTSPVFDSNDSRAGRWSNSSKTECGLHVTDKP
What is the function of this protein?
Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
What are the official names of this protein?
Adenosine 5'-phosphosulfate reductase, APS reductase, 5'-adenylylsulfate reductase, Thioredoxin-dependent 5'-adenylylsulfate reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_CHLAD
Sequence: MLTRRIIPCLDVKAGRVVKGVKFLNHRDAGDPVALAAAYNAAGADELVFYDITASSDERAIMVEVVERTAAEVFIPLTVGGGLRSVEDMYRMLRAGADKVSLNTAAVYNPHLIAEGARRFGSQCIVLSVDAKRVNAPGEPPRWEVFTHTGANPRPTGLDAIEWIKRGIDLGAGEICINSMDADGARTGYDLELLQAITAISPVPVIASGGAGSPADMYRGIVEGGADAVLAASIFHFGDYSIADVKRYLAERGVPVRQTFGSEVGTSTGA
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PARL_DANRE
Sequence: MAWRSCFMKWTQINSINASSLCPKSTRLNIHPQQRCGFRKTERPSESKKGVQETEAEAGGHNRAVPPKPVPPLPPRRPHQLFRPLVFTVGFTGCSFGAAAILQYESVKSRVQLAIEEAKEEKRDTLLEGHDTTYWHNWWNQLSNFQKQVILLISAVDDFWSGLSEGQKTVTGIIALNTVVLCCWRVPAMQRFLVKYFTSNPASKTRCLPMVLSSFSHYSVIHMVVNMYVLWTFSSSIVSLLGREQFLALYLSGGVISTFVSYVFKTATGRLGPSLGASGSIMTVLAAVCTKIPEAKLGIVLLPVISFSAGNALKALVALDIAGLVLGWRFFDHAAHLGGALFGVWYIGYGHELIWRKREPLIKFWHELRNMSPGRPGPGGGGG
What is the function of this protein?
Required for the control of apoptosis during postnatal growth.  Essential for proteolytic processing of an antiapoptotic form of opa1 which prevents the release of mitochondrial cytochrome c in response to intrinsic apoptotic signals (By similarity).
What are the official names of this protein?
Presenilins-associated rhomboid-like protein, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: COX3_HORSE
Sequence: MTHQTHAYHMVNPSPWPLTGALSALLMTSGLAMWFHFNSTLLLAMGLLTNILTMYQWWRDIIRESTFQGHHTSIVQKGLRYGMILFIISEVFFFSGFFWAFYHSSLAPTPELGGCWPPTGIHPLNPLEVPLLNTSVLLASGVSITWAHHSLMEGNRKNMLQGLFITISLGVYFTLLQASEYYEASFTISDGVYGSTFFVATGFHGLHVIIGSTFLIVCFLRQLKFHFTSSHHFGFEAAAWYWHFVDVVWLFLYVSIYWWGS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MOTB_ECO57
Sequence: MKNQAHPIIVVKRRKAKSHGAAHGSWKIAYADFMTAMMAFFLVMWLISISSPKELIQIAEYFRTPLATAVTGGDRISNSESPIPGGGDDYTQSQGEVNKQPNIEELKKRMEQSRLRKLRGDLDQLIESDPKLRALRPHLKIDLVQEGLRIQIIDSQNRPMFRTGSADVEPYMRDILRAIAPVLNGIPNRISLSGHTDDFPYASGEKGYSNWELSADRANASRRELMVGGLDSGKVLRVVGMAATMRLSDRGPDDAVNRRISLLVLNKQAEQAILHENAESQNEPVSALEKPEVAPQVSVPTMPSAEPR
What is the function of this protein?
MotA and MotB comprise the stator element of the flagellar motor complex.  Required for the rotation of the flagellar motor.  Might be a linker that fastens the torque-generating machinery to the cell wall (By similarity).
What are the official names of this protein?
Motility protein B, Chemotaxis protein MotB.
What is the protein family that this protein belongs to?
Belongs to the MotB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: KARG_ARTSF
Sequence: MVDAGTLEKLEAGFQKLQAATDCKSLVKKYLTREVFDQLKTLKTSLGATLLDVIQSGVENLDSGVGIYAPDAESYTLFAPLFDPIIEDYHIGFTKNDSHPPSDFGDVNTLGDLDPDNKFVISTRVRCGRSLQGYPFNPCLTEAQYKEMEDKVSSTLNGLDGELKGTFYPLTGMAKEVQQQLIDDHFLFKEGDRFLQAANACRYWPTGRGIYHNDAKTFLVWCNEEDHLRIISMQKGGDLKAVYARLVNAVNEIEKRIPFSHHDRLGYLTFCPTNLGTTIRASVHIQLPKLAADRKRLEEVASKYNLQVRGTRGEHTEAEGGIYDISNKRRMGLTEYQAVKEMYDGIAELIKLEQSA
What are the official names of this protein?
Arginine kinase, AK.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.
Protein: CWC15_DROME
Sequence: MTTAARPTFDPARGGSGRGEKDLSALSKQYSSRDLPGHTKLKYRETGQGTSDENRNRDFRKELEEREREARSGTGATSSSSGKALPSIVRKAIEANNAGGGSSAAKRSKPDAGQQQAQQAAQQQAANMDADEPLDNDSSDSDSDSDDDDAALLAELQKIKQERLQETARRESEKKQEDERIRMENILSGNPLMNYEPGTAASAAGRASGLGGDLKIKRRWDDDVVFKNCARSAPDKKTHFVNDALRSDFHKKFMDKYIK
What is the function of this protein?
Involved in pre-mRNA splicing.
What are the official names of this protein?
Protein CWC15 homolog.
What is the protein family that this protein belongs to?
Belongs to the CWC15 family.
Protein: ATPA_FRATO
Sequence: MQLSPSEISGLIKQRIEKFDNSVELKSEGTIVSVADGIVTIYGLNDVTAGEMIKLPGDVYGLALNLNTDSVGAVVLGDYEHIKEGDKAYCTGRILEVPVGEALLGRVVDALGNPIDGKGEVATDLTSPIEKIAPGVIWRKSVDQALQTGIKSIDSMVPIGRGQRELIIGDRQIGKTAIAVDTIINQKGTGVKCIYVAIGQKASTIANIVRQLEEYGAMEHTIIVAATASDSAALQYIAPYAGCSMGEYFRDRGQDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVNEEYVEKFTNGEVKGKTGSLTALPIIETQAGDISAFVPTNVISITDGQIFLETDLFNSGLRPAINPGNSVSRVGGAAQTKIIKKLGGGIRLALAQYRELEAFSQFASDLDEATRAQLNRGQRVTELLKQKQFSTLSVALMALSLYAADNGYLDNLEVSEVIPFESALHALAETKYSDVIAEINETDKYDADIADKLKIIVEDCKANQAW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SYP_SOLM1
Sequence: MRLSRYYAPTLKETPAEAEVISHKLLLRAGMIRKLTAGIYTYLPLGLKALNNVAKIVREEMDRAGALEILMPAVQPADLWKESGRWDFYGRELLRFVDRHDRESCLGPTHEEVVTDLVRHEIRSYRQLPVNLYQIQTKFRDEIRPRFGLMRGREFVMKDAYSFDKDDSGADASYWGMYEAYARIFKRLGLKFRAVAADSGAIGGSFSHEFMVLADTGEDTIVACPACDYGANVEKAEAICPPAGDLAPCPAAEKIATPGQHTVEELAAFLKVPVASVIKTLLYVADGKTVAALVRGDRELNEVKFKNLLDAKEDLRLATPEEVTAATGAPVGFAGPVGLSLPVYADRELALANDWVVGANAADAHLLHVDLGRDANVVSYTDLREVAPGDPCPKCGALLDFTKGIEVGHVFKLGLKYSKALNATFLDEAGKEQFMIMGCYGIGVSRIVASAIEQNHDDGGIVFPPTIAPFEAALINLSPKDETACAKADEIYAALTAAGIETLLDDRDERPGVKFKDADLMGHPIQLTLGGKGLARGIVETKDRRTGEKGELPLEGFFEAFAAWRAGVREGWGLE
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.