PharMolix/UniProtQA huggingface dataset:
Protein: PETL_LOBMA
Sequence: MPTITSYFGFLLAALTITSVLFIGLSKIRLI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 6, Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PetL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: YRKQ_BACSU
Sequence: MAHLKFTLTKKLALLIMVAAIVSGVIFLTLQKITDDLIEGYLSSEEYYHEESARYIQKFSKYVSENELSTSDRKAFGEWVKKENYINLTIFKDQELQYDSIYSESDYGKEKLTQYAQNHSHPVKFSDGEGRVIIDGFYSSRYYDLAFALDLLGATLIFLIIVLFGIRQSLRYLKTIHQEIHILEGGELDYEMTIKGHDELAMIAKSIEDLRKAFLDKLKAIEELQAESRSLVTEMSHDMRTPLTSLIMNLEFAKKEGGEAGASKDRYVANAYGKALQLKSLSDNLFAYFLLNKEYEADLETVAVKEVIYDLISDQIAILHQEHFRVHISGELPETYINVNLEELGRVFDNVMSNLLKYADPEEKISITFVSDQEIFEIHVSNTIKLADITPESNGLGERSIARMMSRMQGQFHSIQKNSKYYIVLRFWNTKM
What is the function of this protein?
Member of the two-component regulatory system YrkQ/YrkP.  Probably activates YrkP by phosphorylation.
What are the official names of this protein?
Sensor histidine kinase YrkQ.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: METE_STRA5
Sequence: MVKVSNLGYPRLGEQREWKQAIEAFWAGNLEQKDLEKQLKQLRINHLKKQKEAGIDLIPVGDFSCYDHVLDLSFQFNVIPKRFDEYERNLDLYFAIARGDKDNVASSMKKWFNTNYHYIVPEWEVETKPHLQNNYLLDLYLEAREVVGDKAKPVITGPITYVSLSSGIVDFEATVQRLLPLYKQVFQDLIDAGATYIQIDEPIFVTDEGELLVDIAKSVYDFFAREVPQAHFIFQTYFESAVCLDKLSKLPVTGFGLDFIHGRAENLAAVKQGLFREKELFAGIVNGRNIWAVNLEETLALLEEIGPFVKRLTLQPSSSLLHVPVTTKYETHLDPVLKNGLSFADEKLKELELLASAFDGNKTKGYHEALSRFSALQAADFRHVALESLAEVKLERSPYKLRQALQAEKLQLPILPTTTIGSFPQSPEIRKKRLAWKRGNLSDSDYKDFIKTEIRRWIAIQEDLDLDVLVHGEFERVDMVEFFGQKLAGFTTTKLGWVQSYGSRAVKPPIIYGDVKHIQPLSLEETVYAQSLTKKPVKGMLTGPITITNWSFERDDISRSDLFNQIALAIKDEIQLLEQSGIAIIQVDEAALREGLPLRQQKQQAYLDDAVAAFKIATSSVKDETQIHTHMCYSKFDEIIDSIRALDADVISIETSRSHGDIIESFETAVYPLGIGLGVYDIHSPRIPTKEEIIVNIQRSLKCLSKEQFWVNPDCGLKTRREAETIAALEVLVSATKEVRQQLDN
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: RPOC_BORT9
Sequence: MKEIKDFEKIRIKIASPDQIRSWSYGEVKKSETINYRTLRPEKDGLFCERIFGTTKEWECYCGKFKSIRYKGIICDRCNVEVTHFKVRRERMGHIELSAPVAHIWYYKYIPSRIGLLLDITASNLNSILYYEKYIVIEPGDTDLKKMQLLNEDEYSEAKERYGMSFSASMGAEAIKTLLENLDLDELSSKLRLQMIDKDDKTDKKLLRRLEIIENFKVSGNKPEWMIMDVLPVIPPEIRPMVQLDGGRFATSDLNDLYRRVINRNNRLRKLLLLNAPEIIVRNEKRMLQESVDSLFDNSHKRKVVKGTSNRPLKSLSDALKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLHQCGIPAKMALELFKPFVIRKLIESESVFNIKRAKSLIEQEVDEVWQILDNVIKEHPVLLNRAPTLHRLGIQAFEPVLVEGKAIKLHPLVCHAYNADFDGDQMAVHVPLTPAAQAESWALMLSTNNLLNPANGHPIVFPSQDIVLGLYYLTMERKNVVGEGRKFSNFNHVLLAINNKSLDYNARIYVKVDGEYIETTAGCVVFNEALPGKISFVNKTLSDYELQNLISEVYVVYGSSIVIEMLDIIKELGFKYATKFGCTISMSDIIVPEEKKVYVDKANREIAKIQNDYTKGVITGEERYNNVVSVWSKTNEELTNKMMEILKKDRDGFNVIYMMADSGARGSRNQIRQLAGMRGLMAKTSGDIIELPIISNFKEGLSVIEFFISTNGARKGLADTALKTADAGYLTRRLVDIAQDVVVRIEDCGTINGIKVEALKNGEEIVEPLREKAVGSYSIERIKSPITGEIILDVNEEITEDKIKLLETVGIDKLVIRSVLTCEAEHGVCQKCYGRDFSNNKPVNIGEAVGIIAAQSIGQPGTQLTMRTFHIGGVAQAGSEDDKIALKNSFILNGLEGFNVQVDGGLLFTRKGTLRVINVIYEEDIKDIKEFKVLDSQKVIKGMPLFTSKDGIDVLSSHIGYVRIKDNKLMIVSEEQEISLKTGTKLEVNVGDYVEAGRVIGTFDPFAEPIIAEVRGKVKFKDIILGTTLKEEINLETGNIEKRITDQVFESLDPRILIINDRGIEIASYVLPGDAYLQVEDGQDIDIGDIIAKLSKGSEKTQDITGGLPRVNDLFETRIPKNLTEMAKVSGVVQFKAIQKGKRLINVLDEYGVEHKHYIPAGKHLLVRDGDVVKAGDMLCDGRINPHDVLEILGGISLQEFLLAEIQDVYRKQGVSINDKHIGVIIKQMMKKVKIVSVGDTNFVYNQKVDKHTFYEQNKRVIEQGGEPAVASPILIGITKASLNIDSFISAASFQETTKVLTDASIAGSVDDLKGLKENVVIGHLIPTGTGMNLYKRVKVRENSSSEM
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: RS6_CLOB8
Sequence: MRKYETIFILNPSFDEETVKANIEKFKGVIENGGGTVENVDFWGKRKLAYEISKVSEGFYTLVNFTANPELPRELDRIFRITDGVIRHIIVNEQV
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: RT07_DICCI
Sequence: MVNTFDKTFEKRLINAFMRKGNYIKAERIYFTVLNRLTTLGIQNPYKFLRETLIKMTPIMGVVKKKRGVKEKIYPKYLEPRMGEKYAIKWLLKKLEKSKGDLLINNIVDEFLKASKDQGEVLKEKWALYKEVRYALSFNKAKKKKVSFIESKIKATKRRKWY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S-like rRNA where it nucleates assembly of the head domain of the small subunit.
What are the official names of this protein?
Ribosomal protein S7, mitochondrial, MRP-S7, S7mt.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: THII_LISMO
Sequence: MEFDRMLIRYGELSTKGKNRKQFVTKLAQNVKRAMTDLPEVRIHGERDRMYIILNGADYQLAEERLKPIFGIQSFSPAVRVNLDVEEVKAAALALVQDAHEENGTFKVAARRSHREFPLDSNEINQEIGAYVLQNMEDLTVNVKNPDVKLTIDVRKEGVFLSCRTILGAAGLPVGSSGRAMLMLSGGIDSPVAGYLAQKRGVEIEAVHFHSPPYTSEQAKQKAIDLAAKLAKYSGQVQMHIVPFTEIQEVIKQQIPESVIMTVTRRMMLRITDELRRKRNGLAIVNGESLGQVASQTLESMLAINAVTATPIIRPVVSMDKNEIIQIAQKIDTYNLSVQPFEDCCTIFTPPSPKTKPKLDKIEHYESFTDFDALIAKALDNIETISVNVAETAQVKDEFADLF
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CF50_DICDI
Sequence: MNKMNNIFLIISSIILSIVIFVSGECAIDFSSEISVGISDSQWSCLASNNQRVIIQVWSGGGQYNSNISSVVSAAEQAGFDNIDLYAFLCSECDGNYPASSAIQSLVSSLKSDGINFNMLWIDVEQCDGCWGAESDNADYVQEAVETAQGLGVLVGVYSSEGEWPQTVGNLSTLSQYPLWYAHYDDNPSFSDTAFYEFGGWTSPAMKQYIGNTNQCGVSVDLDFYGSGSGCSTSSGSASGSASGSASGSASGSNSGSSNSGSSNSGSSNSGSNSGSSNSGSGNSGSSNSGSASGSGTGSGSSI
What is the function of this protein?
Cell-counting factor that limits the maximum size of the multicellular structure during aggregation.  Has a very low lysozyme activity.
What are the official names of this protein?
Counting factor 50, 1,4-beta-N-acetylmuramidase 1, GH family 25 lysozyme 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 25 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PARP1_CRIGR
Sequence: MAEASERLYRVEYAKSGRASCKKCSESIPKDSLRMAIMVQSPMFDGKVPHWYHFSCFWKVGHSIRQPDVEVDGFSELRWDDQQKVKKTAEAGGVAGKGQDGSGGKSEKTLGDFAAEYAKSNRSTCKGCMEKIEKGQVRLSKKMLDPEKPQLGMIDRWYHPTCFVKNREELGFRPEYSASQLKGFSLLSAEDKEVLKKQLPGVKSEGKRKGDEVDGADEVAKKKSKKGKDKDSKLEKALKAQNDLIWNIKDELKKACSTSDLKELLIFNQQQVPSGESAILDRVADGMAFGALLPCKECSGQLVFKSDAYYCTGDVTAWTKCMVKTQTPSRKEWVTPKEFREISYLKKLKVKKQDRIFPPETSAPAPPHLPPSVTSAPTAVNSSCPADKPLSNMKILTLGKLSQSKDEAKATIEKLGGKLTGSANNASLCISTKKEVEKMGKKMEEVQAANVRVVCEDFLQDVAASTKSLQELLSAHSLSSWGAEVKVEPVEVAAPKGKSAAPSKKSKGLYKEEGVNKSEKRMKLTLKGGAAVDPDSGLEHSAHVLEKGGKVFSATLGLVDIVKGTNSYYKLQLLEDDKESRYWIFRSWGRVGTVIGSNKLEQMPSKEDAVEHFMKLYEEKTGNAWHSKNFTKYPKKFYPLEIDYGQDEEAVKKLTVKPGTKSKLPKAVQELVGMIFDVESMKKALVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEVIRKYVKNTHATTHNAYDLEVMDIFKIEREGESQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSASITLEGVEVPLGTGIPSGVNDTCLLYNEYIVYDIAQVNLKYLLKLKFNFKTSLW
What is the function of this protein?
This cleavage form irreversibly binds to DNA breaks and interferes with DNA repair, promoting DNA damage-induced apoptosis.
What are the official names of this protein?
Poly [ADP-ribose] polymerase 1, PARP-1, ADP-ribosyltransferase diphtheria toxin-like 1, ARTD1, DNA ADP-ribosyltransferase PARP1, NAD(+) ADP-ribosyltransferase 1, ADPRT 1, Poly[ADP-ribose] synthase 1, Protein poly-ADP-ribosyltransferase PARP1.
What is the protein family that this protein belongs to?
Belongs to the ARTD/PARP family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Chromosome. Note=Localizes to sites of DNA damage.
Protein: HDA_SALTI
Sequence: MSSWVEVSLNTPAQLSLPLYLPDDETFASFWPGDNASLLAALQNVLRQEHSGYIYLWAREGAGRSHLLHAACAELSQRGDAVGYVPLDKRTWFVPEVLDGMEHLSLVCIDNIECVAGDELWEMAIFDLYNRILESGKTRLLITGDRPPRQLNLGLPDLASRLDWGQIYKLQPLSDEDKLQALQLRARLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDHASITAQRKLTIPFVKEILKL
What is the function of this protein?
Mediates the interaction of DNA replication initiator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN).  Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinitiation, a process called regulatory inhibition of DnaA or RIDA (By similarity).
What are the official names of this protein?
DnaA regulatory inactivator Hda.
What is the protein family that this protein belongs to?
Belongs to the DnaA family. HdA subfamily.
Protein: TRPC_MYCSJ
Sequence: MSSATVLDSIIEGVRADVAAREAVVSLTEIKERAQRAKPPLDVMAALREPGIGVIAEVKRASPSRGALAQIGDPADLARAYQDGGARVISVLTEQRRFNGSLDDLDAVRAAVSIPVLRKDFIVRPYQIHEARAHGADMLLLIVAALEQPVLESLLERTESLGMTALVEVHTEAEADRALQAGARVIGVNARNLKTLEVDRDCFARIAPGLPSNVIRIAESGVRGPADLLAYAGAGADAVLVGEGLVTSRDPRSAVADLVTAGTHPSCPKPSR
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: MNTP_XANOM
Sequence: MSPFSIVLIGFAMSTDAFAAAIGKGAAMRKPQWRDALRAGLIFGCIEAITPVIGWVLGRAASSYLSAYDHWIAFVLLGALGTHMMIAGLRNGPDDANDAEAKTPKRHGLLGLATTGFATSIDAMAVGVSLAFLDVHIGVVAVVVGLCTFSMVTAGVMLGRALGNLIGKRAEILGGLILVIVGSVILYEHLGAAT
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: OR6T1_HUMAN
Sequence: MNPENWTQVTSFVLLGFPSSHLIQFLVFLGLMVTYIVTATGKLLIIVLSWIDQRLHIQMYFFLRNFSFLELLLVTVVVPKMLVVILTGDHTISFVSCIIQSYLYFFLGTTDFFLLAVMSLDRYLAICRPLRYETLMNGHVCSQLVLASWLAGFLWVLCPTVLMASLPFCGPNGIDHFFRDSWPLLRLSCGDTHLLKLVAFMLSTLVLLGSLALTSVSYACILATVLRAPTAAERRKAFSTCASHLTVVVIIYGSSIFLYIRMSEAQSKLLNKGASVLSCIITPLLNPFIFTLRNDKVQQALREALGWPRLTAVMKLRVTSQRK
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 6T1, Olfactory receptor OR11-277.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL17_RHOJR
Sequence: MPKPKKGARFGGSASHQKAIFANLATALFEHGRITTTESKAKALRPYAEKLVTHAKAGTLAHRREVLKVIRNKDVVHTLFAEIGPFYADRDGGYTRIIKTVPRKGDNAPMAIIELVKEKTVTSEADRARRVKASQDAPAAAPAEENVVEAVEAEATDAEVENADAVVEAIEDETATAADAPEAEEAKKD
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: MYC2_OTOBE
Sequence: MRSCTVSTMPRMICRNADLEFDWLQPCFYPDEDDFYFSGPNSTPPGEDIWKKFELLPTPPLSPSCAFLELSTEPSDWASEMMLTEADLWGNPDEEDVFGPGGLGSLTPNPVILRDCMWSGFSAREKLERAMSEKMQHGHEPAATGPATQVPGAGAASTAGRGHSGTAGAALPAELAHPAAECVDPAVVFLLPVSKRNPVPVRVAPARAPARAPAVGAAVARAAAPASAAVAAPPGLSSRPPNGGDHKVLSTSGEDALSDEVDEEEDEEEEIDVVTVEKSCKTGGTTFTLTVSPKNTALGLRREQSRELILQRSVPIYQQHNYAAPSPYVENEDAPPQKKIKREVSPHPLKSVIHPKGKSFSPRKSDSEDSVRRRNHNILERQRRNDLRSSFTTLRDHVPELVKNEKAAKVVILKKACEYVHYLQAKEHQLLMEKEKLQARQQQLLKIIELAWTF
What are the official names of this protein?
N-myc 2 proto-oncogene protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: TTCA_RUEST
Sequence: MLDQDLDDIHPLFQGAPQTTEFKKLRKRIVRYTREAVEQYGMVERREDGSLPKWLVCLSGGKDSYTLLAVLYELKWRGLLPVDLLACNLDQGQPGFPATVLPEFLEKMQVPHRIEYQDTYSIVMDKVPQGRTYCALCSRLRRGNLYRIAREEGCSAVVLGHHRDDILETFFMNLFHGGRLATMPPKLVNEEGDLFVFRPLAHVAEADCEKFARAMNYPIIPCDLCGSQDGLQRQQVKQILDTWESNSPGRRQVMFRALMNARPSHLLDPKLFDFTGLALKNIDNSTETEEIPELR
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_ROSS1
Sequence: MSLFVTFEGPEGSGKSTQARLLYESLHARRFPVILTREPGGTRIGDLIRRIVLDLQHTEMAPTAEMLLFSAARAQLVSEVIRPYLEQGGIVLCDRYADSTFAYQGYGLGRDLAELRVITAAATGGLRPDITFYLDISAAEGLERKRRKGARSTGQRGANNDEWNRLDARELEYHQRVEAGYRELIAADPERWRVLDARQSIEALAEQIGAIVEPYLASITRLETVL
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: WHIA_BEUC1
Sequence: MSLTAAVKDELARVRVDKISSRKAEVSATLRFAGGLHIISGRIVIEAELDAAIAARRLRVAIAEVYGHVSDIIVVSGGALRKGNRYVVRVVRDGEALARQTGLLDSRGRPVRGLPPQVVSASIGDTVAAWRGAFLAHGSLTEPGRSSALEVTCPGPEAALALVGAARRLGITSKAREVRGVDRVVIRDGDAISAILTRMGAHDAVLAWEERRMRREVRGTANRLANFDDANLRRSARAAVAASARVERAFEILAEDVPDHLVEAGRLRLENKQASLEELGQLSDPPLTKDAVAGRIRRLLAMADKKASDLGIPDTESILTPEMLDL
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: SYV_XANOR
Sequence: MTTLASSYDPSSFESRLYAQWEAAGYFVPSDTGEPYTVLLPPPNVTGTLHMGHAFQQTLMDALVRYHRMRGYDTLWQVGTDHAGIATEMVVSRNLALEGKGETRDSLGREGFIAKVWEWKAASGDTIERQMRRLGTSSDWSRSTFTMDPQPSAAVNEAFVRWYEQGLIYRGQRLVNWDPVLKTAISDLEVENVEEDGFLWSIRYPLADGVTYEHIEHDADGNETLRETRDYLVVATTRPETMLGDTAVMVHPEDARYLTLHTARIVLPLTGRHVPVITDDYVDRAFGTGVVKVTPAHDFNDYQVGERHNLPLVNLFTADAKIIDPRKQYPDDESPFVNAGIDWRELDQIQRKRLGQHLAYKIPAQYIGLDRYDARKLVLSELEDLSILVETKPHKLQVPRGDRTGQVIEPYLTDQWFVKMDALAKRGLELVESGQIQFVPPNWINTYRHWMENIQDWCISRQLWWGHRIPAWFDDAGHCHVGHDEAEVRAKHGLGAEIALHQDSDVLETWFSSQLWPFSTLGWPDSQAMAERGFARYLPSSVLVTGFDIIFFWVARMIMATDSFTGQVPFRDVYITGLIRDAQGQKMSKSKGNVLDPLDIIDGISIEDLVAKRTNGLMQPRMAEKIEKATRKEFPDGIIAHGADALRFTIAALATHGRDIKFDLGRAEGYKNFCNKLWNATRFVLMNTEGARFTGVPQPRTEAEKWILARLDKVTAETHAHYANYRFDLLAQSLYEFAWNAFCDWFVELAKPALNNQDTDAAASTRHTLLYVLESLLRLLHPLTPFVTEELWQQVVPRLGITTATISLQRFPQVGDVDTSGYATAEADVEWLKSMVSALRRVRSELNVPPSKQVRLLLQADTADERPRVARFASQLSFLLKLERIDWLDAGQDTPPSAAAIVGELTLLVPLEGLVDMDAERMRLDKEIKRVKGEIGKCNGKLGNATFVQNAPAVVVDQERARLADWTTQLAGLREQRGKL
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TEF_MOUSE
Sequence: MSDAGGGKKPPVEPQAGPGPGRAAGERGLSGSFPLVLKKLMENPPRETRLDKEKGKEKLEEDESAAASTMAVSASLMPPIWDKTIPYDGESFHLEYMDLDEFLLENGIPASPTHLAQNLLLPVAELEGKESASSSTASPPSSSTAIFQPSETVSSTESSLEKERETPSPIDPSCVEVDVNFNPDPADLVLSSVPGGELFNPRKHRFAEEDLKPQPMIKKAKKVFVPDEQKDEKYWTRRKKNNVAAKRSRDARRLKENQITIRAAFLEKENTALRTEVAELRKEVGKCKTIVSKYETKYGPL
What is the function of this protein?
Transcription factor that binds to and transactivates the TSHB promoter.  Binds to a minimal DNA-binding sequence 5'-[TC][AG][AG]TTA[TC][AG]-3' (By similarity).  Also activates the telokin promoter in smooth muscle-specific and calcium-dependent manner.
What are the official names of this protein?
Thyrotroph embryonic factor.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. PAR subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: TCAA_STAA8
Sequence: MKSCPKCGQQAQDDVQICTQCGHKFDSRQALYRKSTDEDIQTNNIKMRKMVPWAIGFFILILIIILFFLLRNFNSPEAQTKILVNAIENNDKQKVATLLSTKDNKVDSEEAKVYINYIKDEVGLKQFVSDLKNTVHKLNKSKTSVASYIQTRSGQNILRVSKNGTRYIFFDNMSFTAPTKQPIVKPKEKTKYEFKSGGKKKMVIAEANKVTPIGNFIPGTYRIPAMKSTENGDFAGHLKFDFRQSNSETVDVTEDFEEANISVTLKGDTKLNDSSKKVTINDHEMAFSSSKTYGPYPQNKDITISASGKAKDKTFTTQTKTIKASDLKYNTEITLNFDSEDIEDYVEKKEKEENSLKNKLIEFFAGYSLANNAAFNQSDFDFVSSYIKKGSSFYDDVKKRVSKGSLMMISSPQIIDAEKHGDKITATVRLINENGKQVDKEYELEQGSQDRLQLIKTSEK
What is the function of this protein?
Plays a major role in decreasing resistance to glycopeptide antibiotics.
What are the official names of this protein?
Membrane-associated protein TcaA.
What is the protein family that this protein belongs to?
Belongs to the TcaA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: ACP_ERWT9
Sequence: MSTIEERVKKIIGEQLGVKQEEVVNTASFVEDLGADSLDTVELVMALEEEFDTEIPDEEAEKITTVQAAIDYINGHQA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCS2_ECOHS
Sequence: MPLPDFHVSEPFTLGIELEMQVVNPPGYDLSQDSSMLIDAVKNKITAGEVKHDITESMLELATDVCRDINQAAGQFSAMQKVVLQAVTDHHLEICGGGTHPFQKWQRQEVCDNERYQRTLENFGYLIQQATVFGQHVHVGCASGDDAIYLLHGLSRFVPHFIALSAASPYMQGTDTRFASSRPNIFSAFPDNGPMPWVSNWQQFEALFRCLSYTTMIDSIKDLHWDIRPSPHFGTVEVRVMDTPLTLSHAVNMAGLIQATAHWLLTERPFKHQEKDYLLYKFNRFQACRYGLEGVITDPHTGDRRPLTEDTLRLLEKIAPSAHKIGASSAIEALHRQVVSGLNEAQLMRDFVADGGSLIGLVKKHCEIWAGD
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: PHOX2_ARATH
Sequence: MGKSGGRKKKSGGSNSNSSQVNSSETSGLSKPSTIVNGGVDFDASIFLKRAHELKEEGNKKFQARDYVGALEQYENGIKLIPKSHPDRAVFHSNRAACLMQMKPIDYESVISECSMALKSQPGFTRALLRRARAFEAVGKFDLAVQDVNVLLGSDPNHKDAGEISKRLKTALGPHQDLQSRPSPAALGASAALGGPIAGLGPCLPSRNVHKKGVTSPVGSVSLPNASNGKVERPQVVNPVTENGGSVSKGQASRVVLKPVSHSPKGSKVEELGSSSVAVVGKVQEKRIRWRPLKFVYDHDIRLGQMPVNCRFKELREIVSSRFPSSKAVLIKYKDNDGDLVTITSTAELKLAESAADCILTKEPDTDKSDSVGMLRLHVVDVSPEQEPMLLEEEEEEVEEKPVIEEVISSPTESLSETEINTEKTDKEVEKEKASSSEDPETKELEMDDWLFDFAHLFRTHVGIDPDAHIDLHELGMELCSEALEETVTSEKAQPLFDKASAKFQEVAALAFFNWGNVHMCAARKRIPLDESAGKEVVAAQLQTAYEWVKERYTLAKEKYEQALSIKPDFYEGLLALGQQQFEMAKLHWSYLLAQKIDISGWDPSETLNLFDSAEAKMKDATEMWEKLEEQRMDDLKNPNSNKKEEVSKRRKKQGGDGNEEVSETITAEEAAEQATAMRSQIHLFWGNMLFERSQVECKIGKDGWNKNLDSAVERFKLAGASEADIATVVKNHCSNEAAATEGDEKKVPAP
What is the function of this protein?
Required for plastid separation and partitioning during cell division (PubMed:22025705).  Not involved in plastid constriction or in the organization of cytoplasmic actin cables (PubMed:22025705).  Contributes to polar growth of root hairs (PubMed:28096376).
What are the official names of this protein?
Protein CLMP1, CLUMPED CHLOROPLASTS 1, Protein MADB2, Protein PHOX2, Putative myosin adapter B2.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localized to distinct foci in the cytoplasm, which frequently colocalize with the cell periphery and with chloroplasts.
Protein: NRG2_YEAST
Sequence: MSIGYKDNLMSTILAKDRKCEFPINFECSPSQITLMPEMFSFNNERKYQTLIPLMKTSHLIDDDLKDKLNKCAFDFFSGKQANRTSDGTISRLTASGKTSPILPLQNINIVKAENTGNGKSDPYSSIKISKPTKTVIKLKSTKTNTAGQRTRHFCKICSTGFTTSGHLSRHNRIHTGEKNHICPHEGCGQRFSRHDNCNQHYRTHANKKKRNWKRREASS
What is the function of this protein?
Transcriptional repressor.
What are the official names of this protein?
Probable transcriptional regulator NRG2.
What are the subcellular locations of this protein?
Nucleus.
Protein: MIAB_ALIB4
Sequence: MSSNKKLFIQTLGCQMNDTDSQHIQAELEKHKGYVTTQNIEDADLIIINTCSVRERPVQKLFSEIGQFNKKKKEGAKIGVCGCTASHLGQDIIKRAPYVDFVVGARNISKIKDVVDVKGAVEVSIDNDESTYEFSTAKTNKYRASVNISVGCDKKCTYCIVPSTRGEEISIPPEMIVEQVRKSVEQGAVEVMLLGQNVNSYGRKFSDKREKYTFTKLLQDVSKIDGLERIRFTSPHPLHMDDEFIEEFAKNPKISKCIHMPLQSGSTSVLKAMKRGYSKEWFLNRASKMRELVPNLRITTDIIVAFPGETQEDFLDTLDVVEQVKFDQIFNFKYSPRPGTEALNLKDKELPDEIGSQRLIDLIELHKRYLEESMPKLIGETLNILVESLKPNGEVCGYTDNYLQVFAKGSDELLGKFVNVKITDVTRTSLKGEVVN
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECB_NITEC
Sequence: MTEPQQQPVFVIEKVYVKDLSLEIPHAPQVFLERESPEINLQLATSDNVIEGEIHEVIVTATVTARLKEKDKVMFLVEAHQAGIFRIRNVPGNEIEPVLGVLCPNILFPYLRETISDTVTRAGFPPVILNPVNFEAIYQQKQQEAAVSQPDQPVDNTTRH
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEC_ALISL
Sequence: MSTAIVVFSGGQDSTTCLIQALTHYDHVHCITFDYGQRHNQEIEVAKSVALDLGATSHKVMDVGLLNELAVSSLTRDNIPVSHELQENGLPNSFVPGRNILFLTLAGIYAYQLGAESVITGVCETDFSGYPDCRDEFVKSINQSLVLGMDRKLKIDTPLMWLNKAETWALADKYGKLDYVRNQTLTCYNGVIGDGCGDCPSCDLRKNGLDDYLANKESVMADLESKI
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.