PharMolix/UniProtQA huggingface dataset:
Protein: YHEC_BACSU
Sequence: MITLGFMSLSRQHEADYSAELAKRAPEFGIRFIRFTPFDISPDTLRVKASVYHSASSTWNETEMAIPDYIYDRCFYGKDSHSQKAKPIVEWLKKYPKTEFIGRGLPDKWTVLHDLQQHSVINPYIPETIKVSRYEQIHSFLSKEKACILKPAFGAGGRGVILLKLGKKNITATYHIGKDKQTKTFSNQTSFKTWCKKVLQHQYLLQPYLNIQDKEQYPCDIRLFMEKNEAGEWNTVGKAVRRGYKHGLLANLSGGSDALTFDSWFEDIPKKQQVVLLDDVFSITQSVPYYLDERYGPLFELGLDICLAKDGRIWILDINSKPGRKSILRVSPEQKEQLYTCPLKRCQYLFSEQSQKGVLPRES
What is the function of this protein?
Involved in sporulation.
What are the official names of this protein?
Endospore coat-associated protein YheC.
What is the protein family that this protein belongs to?
Belongs to the YheC/YheD family.
What are the subcellular locations of this protein?
Forespore outer membrane; Peripheral membrane protein. Spore coat.
Protein: HSLV_CHLPB
Sequence: MERYGKPELRATTVLGVIRNGKAALGSDGQMTLGNTVIKHSTRKIRRLRQAQIVTGFAGATADAVTLLDRFEEKLQTYGGLLERAAVELARDWRTDKYLRRLEAMLAVVSPEKALIISGTGDVIEPEDGIVAIGSGSMFALAAARSLMKHTDLNAADIVRESLLIAADICIYTNDHIVLEEV
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_PSE14
Sequence: MQLNVNDAQAIEVSELTFGGEFNETLVHQAVVAYMAGGRQGSKQQKTRSDVRGGGKRPWRQKGTGRARAGTIRSPIWRGGGTTFAARPQDHTQKLNKKMYRAALRSILAELVRTDRLVVVQDFAVEAPKTKDLLSKLTGMGLTDVLIVSDAVDQNLYLAARNLPHVDVRDVQGSDPVSLIAYDKVLITVSAVKKFEELLG
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: TRUA_RICAH
Sequence: MYRYKITIEYLGTNLAGWQRQAGVMSVQQILEEAIYKFSGEQVILFGSGRTDAGVHAIGQVAHFDLSKYLEPHKIITAINYFARPYAVVVWHCAIVLNDFHARFSATSRHYIYRIINRPYPSVIDLNRAWWISSPLDVLAMQKAAAYLLGKHDFTSFRASSCQSKSPIKTLTELNIVKGDEEIKLYLSAPSFLHHMVRNIVGSLVLVGKNIWQAEHIKDVLEAKDRKAAGLTAPAYGLYFVKTEY
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: Y456_MYCPN
Sequence: MKFQRKYWGLLSTLGVSSAVALSACAAQARDVYVTSSASDLLKNNSVPMSMFNVSPTSSFFGSKYAGLTTYIATGSNKDDGVNVATQTQEKLVLELATSVKGYKKKDKATSSQKTSTNSSCTTTSSGTSTSGEDDWECIGEIKRQSSSNGQNNQQSKSITEEEKFQEISQKATRYEFAIDTGIKWVDNNGKPVKDASGNDVKLSSKDFERGFEAYILSSELRFNRNGYFIDLMGLDVKKTVGMTKKNGAQVQMKVASSDEKDGEEKTVKITDDAYNPEDYQSTDDSKFNVYLTSPFPFLLSMMSKEFFFPIPHTHPKVKAIKVGKDSPLVYNEKNGSKILDQTKTNFDGIYGGGVNAWRDTWSVGPYYVESFNQSQIVFKRNSEYDTHITPNLPKTREDNEKPIPTMINYFQPGATPEVFYSNYIAGGLSSAEVPYSQQEDARSRFAGTGDLRWVKVQKTAQSAQITYSSRPYVVEGETVKTNSNITETEAKFLYNSESEEALTIRAGINGLINWQNLAIILLPNSGDLNYSIVPFGIFKEKGKNGASVQQKAVSTTEGSDLMNDYYYKIEKEQRLGLIPQREGNYEKNKNVLESATVKINYYSSKATSGQAGAAASAAFAKNNNTSDNTQQNQTSSVEAKSVNVTKHSFVQALKKVGFSGSNPLHFNMKLGNSSLSANGVDYYNAVKQALTELGTADNGEKLIVPEIILGDAQGPTRNEWYIGLSSVLGFSSWSPDYDGVGTWLDAATQLNDQGGGDVITYSSGAHIVRTLLLAASQKDVHSKFTQKIDQQNTASTTSDVTVKKADSSQDSSKSNTEEEKWDDVTSADLFKDDPYVLKNFGDAKAQAAQRSTGSTTSGNGTQASLEFTKKALSLLKFLVDNGILDKEKVKEAIKDPNKYLGKRDKIENGTNKPSKNEDFIGYELKDIYKKAAQLNRFNSIWAEKDTDNAKFLITVVDSYFPVLPVPAAGLNETSPTLLKPWFQFRSAPSGNGTIRDYGFIPENK
What are the official names of this protein?
Uncharacterized lipoprotein MG321 homolog.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: MUTA_BOVIN
Sequence: MLRAKNQLFLLSPHYLRQVKESSGSRLIQQRLLHQQQPLHPEWAALAKKQLKGKNPEDLIWHTPEGISIKPLYSKRDTMDLPEELPGVKPFTRGPYPTMYTFRPWTIRQYAGFSTVEESNKFYKDNIKAGQQGLSVAFDLATHRGYDSDNPRLRGDVGMAGVAIDTVEDTKILFDGIPLEKMSVSMTMNGAVIPVLATFIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMKIIADIFQYTAKHMPKFNSISISGYHMQEAGADAILELAYTIADGLEYCRTGLQAGLTIDEFAPRLSFFWGIGMNFYMEIAKMRAGRRLWAHLIEKMLQPKNSKSLLLRAHCQTSGWSLTEQDPYNNIIRTTIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYMMESLTNDIYDAALKLINEIEEMGGMAKAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYQLEKEESVDVLAIDNTSVRNKQIEKLKKVKSSRDQALAERCLDALTACAASGDGNILALAVDATRARCTVGEITYAMKKVFGEHKANDRMVSGAYRQEFGESKEIAFAIKRVEKFMEREGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHTVGVSTLAAGHKTLVPELIKELNALGRPDILVMCGGVIPPQDYEFLFEVGVSNVFGPGTRIPKAAVQVLDDIEKCLEKKQQSI
What is the function of this protein?
Catalyzes the reversible isomerization of methylmalonyl-CoA (MMCoA) (generated from branched-chain amino acid metabolism and degradation of dietary odd chain fatty acids and cholesterol) to succinyl-CoA (3-carboxypropionyl-CoA), a key intermediate of the tricarboxylic acid cycle.
What are the official names of this protein?
Methylmalonyl-CoA mutase, mitochondrial, MCM, Methylmalonyl-CoA isomerase.
What is the protein family that this protein belongs to?
Belongs to the methylmalonyl-CoA mutase family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Mitochondrion. Cytoplasm.
Protein: YGAV_ECOLI
Sequence: MTELAQLQASAEQAAALLKAMSHPKRLLILCMLSGSPGTSAGELTRITGLSASATSQHLARMRDEGLIDSQRDAQRILYSIKNEAVNAIIATLKNVYCP
What is the function of this protein?
Functions as transcription repressor.
What are the official names of this protein?
Probable HTH-type transcriptional regulator YgaV.
Protein: LYTT_OCEIH
Sequence: MKIHIMIAEDERLAREELMYLLQQENDIILCPSAENGDQLLNLYQEYNPNVIFLDIHMPGINGIEVAKKIRNEFEDKDIIIIFTTAYESYGVQAFEIQATDYLLKPFSEERFKIAMNRIRKTLSTKKVRKPKVDKLVVNLDEKMMVIDPNQIGFAAREGRTVKIHFISNEVIETKMNLKELEEKLSGFPFYRPHRSYLVNMDCIKEITPWFNGAYNLVIKDLAESTIPVSRTAAKGLFDALQGVHH
What is the function of this protein?
Member of the two-component regulatory system LytS/LytT that probably regulates genes involved in cell wall metabolism.
What are the official names of this protein?
Sensory transduction protein LytT.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQRA_HAEDU
Sequence: MITIKKGLDLPIAASPAQVIHNGNTVNEVAMLGEEYVGMRPSMKVREGDLVKKGQVLFEDKKNAGVVFTAPASGTVVAINRGEKRVLQSVVIKVEGDEQITFTRYEAAQLASLSAEQVRANLIDAGLWIAFRTRPFSKVPAVDATPASIFVNAMDTNPLSADPAVIINEYKNDFEYGLTVLIRLGVKVNLVKAAGVNIPTVDGITVHEFAGKHPAGLVGTHIHFIDPVNLTKTVWHLNYQDVIAFGKLFTTGELFTDRVVALAGPQVKTPRLVRTRLGANLSQLTTGELNVGENRIISGSVLSGATASGPVDFLGRYALQVSVLLEGCEKELLGWVMPGSDKYSITRTVLGHFRKKLFNFTTAVHGGERAMVPIGAYERVMPLDIIPTLLLRDLAAGDTDSAQNLGCLELDEEDLALCTYVCPGKNNYGPMLRTALDKIEKEG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit A, Na(+)-NQR subunit A, Na(+)-translocating NQR subunit A, NQR complex subunit A, NQR-1 subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrA family.
Protein: YDGH_BACSU
Sequence: MRAIIKFKWAIAAIVLALTVVLSLFSPNLTELANQKGQAQLPADAVSERANAILKQAGEDNNSISVVFTLDNAIKKETENQLRIIIDKIKKIDGVEEVTSPLSAEKEVKDQLMSKDKKTVLMPVTITGSDKKAEKIADEIYQIVPDDLTAYITGASLINQDFAHSSEEGLKKTEVITVCLIIGLLLIVFRSVVTPFIPIVVVGFSYLISQSILGILVYNVDFPISTFTQTFLVAILFGIGTDYCILLLTRFREELANGHDKKEAALIAYRTGGKTLFISGFAVLIGFSALGFAKFAIFQSAVGVAVGVGILMIILYTLLPLFMVTLGEKLFWPSKKVLSHSDNKLWAFLGRHSVARPFLFIVITVVITLPFILTYDDQISFDSTAEISSDYKSIKALEAIKDGFGEGKAFPINVVVKGDKDLTTADTIPYLGNISKAIEKVDHVDSVMTITQPTGKKIKDLYIDNQLGSVSDGLDKTVKGIADVQSGLTDIENGLNQMAGQTGSASNGGSGGSLGDAADGLGKINQQLQLVSKQISQTGNTAQTVQQLTAISGQLGQIQTGLEQANQQLSGQQAQAGTLTESLKKLSEGVKSANEGLTKVSDGITASSDILEDMSKSPTVRDTGIFIPDQVMKDKDFKKSIDQYSFADGKGVQLSVVLDSNPYSEQAITTINQIKKAVANEVDGTPLENAQIVYGGVTSMNADLKELSTTDFSRTMVIMIIGLFIVLTILFRSMIMPIYMIASLLLTYYTSISITELIFVNGLGNAGVSWAVPFFSFVILIALGVDYSIFLLDRFKEEVHLGIEQGVVRSMSKMGSVIITAAIILAGTFAAMMPSGVNTLMQVASVIIIGLLLYGLVILPLFIPAIIATFGEGNWWPFGRKKGKE
What are the official names of this protein?
Putative membrane protein YdgH.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AMPN_PLAF7
Sequence: MKLTKGCAYKYIIFTVLILANILYDNKKRCMIKKNLRISSCGIISRLLKSNSNYNSFNKNYNFTSAISELQFSNFWNLDILQKDIFSNIHNNKNKPQSYIIHKRLMSEKGDNNNNNHQNNNGNDNKKRLGSVVNNEENTCSDKRMKPFEEGHGITQVDKMNNNSDHLQQNGVMNLNSNNVENNNNNNSVVVKKNEPKIHYRKDYKPSGFIINNVTLNINIHDNETIVRSVLDMDISKHNVGEDLVFDGVGLKINEISINNKKLVEGEEYTYDNEFLTIFSKFVPKSKFAFSSEVIIHPETNYALTGLYKSKNIIVSQCEATGFRRITFFIDRPDMMAKYDVTVTADKEKYPVLLSNGDKVNEFEIPGGRHGARFNDPHLKPCYLFAVVAGDLKHLSATYITKYTKKKVELYVFSEEKYVSKLQWALECLKKSMAFDEDYFGLEYDLSRLNLVAVSDFNVGAMENKGLNIFNANSLLASKKNSIDFSYARILTVVGHEYFHNYTGNRVTLRDWFQLTLKEGLTVHRENLFSEEMTKTVTTRLSHVDLLRSVQFLEDSSPLSHPIRPESYVSMENFYTTTVYDKGSEVMRMYLTILGEEYYKKGFDIYIKKNDGNTATCEDFNYAMEQAYKMKKADNSANLNQYLLWFSQSGTPHVSFKYNYDAEKKQYSIHVNQYTKPDENQKEKKPLFIPISVGLINPENGKEMISQTTLELTKESDTFVFNNIAVKPIPSLFRGFSAPVYIEDNLTDEERILLLKYDSDAFVRYNSCTNIYMKQILMNYNEFLKAKNEKLESFNLTPVNAQFIDAIKYLLEDPHADAGFKSYIVSLPQDRYIINFVSNLDTDVLADTKEYIYKQIGDKLNDVYYKMFKSLEAKADDLTYFNDESHVDFDQMNMRTLRNTLLSLLSKAQYPNILNEIIEHSKSPYPSNWLTSLSVSAYFDKYFELYDKTYKLSKDDELLLQEWLKTVSRSDRKDIYEILKKLENEVLKDSKNPNDIRAVYLPFTNNLRRFHDISGKGYKLIAEVITKTDKFNPMVATQLCEPFKLWNKLDTKRQELMLNEMNTMLQEPNISNNLKEYLLRLTNKL
What is the function of this protein?
Displays aminopeptidase activity with a broad substrate specificity (PubMed:9879894, PubMed:12166515, PubMed:21659511, PubMed:22359643, PubMed:34133730, PubMed:33536500, PubMed:19196988, PubMed:21844374, PubMed:23897806).  Preferentially, cleaves after Leu and Met, but cleaves also after Ala and Arg (PubMed:12166515, PubMed:22359643, PubMed:33536500, PubMed:21844374).  Low activity towards Lys, Phe, Tyr, Trp, Gln, Ser and Gly and negligible activity towards Glu, Asp, Pro, Ile, Thr, Val, His and Asn (PubMed:22359643).  Has dipeptidase activity (PubMed:21659511, PubMed:23897806).  Plays a role in the terminal stages of host hemoglobin digestion by cleaving the N-terminal residue of small hemoglobin-derived oligopeptides (PubMed:21659511, PubMed:34133730, PubMed:21844374).
What are the official names of this protein?
Aminopeptidase N, M1 alanyl aminopeptidase, PfM1AAP, M1 family aminopeptidase, PfA-M1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
Protein: YBEY_STRSV
Sequence: MYIEMVDETGQVSEEILKQTQEILEFAAQKTGKENKEMAVTFVSNERSHELNLEYRDTDRPTDVISLEYKPELDIAVDEEDLLDHPELAEMLEDFDAYIGELFISVDKAREQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAYGLTRK
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDUV1_PANTR
Sequence: MLATRRLLGWSLPARVSVRFSGDTTAPKKTSFGSLKDEDRIFTNLYGRHDWRLKGSLSRGDWYKTKEILLKGPDWILGEIKTSGLRGRGGAGFPTGLKWSFMNKPSDGRPKYLVVNADEGEPGTCKDREILRHDPHKLVEGCLVGGRAMGARAAYIYIRGEFYNEASNLQVAIREAYEAGLIGKNACGSGYDFDVFVVRGAGAYICGEETALIESIEGKQGKPRLKPPFPADVGVFGCPTTVANVETVAVSPTICRRGGTWFAGFGRERNSGTKLFNISGHVNHPCTVEEEMSVPLKELIEKHAGGVTGGWDNLLAVIPGGSSTPLIPKSVCETVLMDFDALVQAQTGLGTAAVIVMDRSTDIVKAIARLIEFYKHESCGQCTPCREGVDWMNKVMARFVRGDARPAEIDSLWEISKQIEGHTICALGDGAAWPVQGLIRHFRPELEERMQRFAQQHQARQAAS
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial, Complex I-51kD, CI-51kD, NADH-ubiquinone oxidoreductase 51 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I 51 kDa subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: RL35_SALA4
Sequence: MPKIKTVRGAAKRFKKTGKGGFKHKHANLRHILTKKATKRKRHLRPKAMVSKGDLGLVIACLPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: HSTN_VIBCL
Sequence: MRNLFIALMLLFSSIAFSQTVENNKKTVQQPQQIESKVNIKKLSENEECPFIKQVDENGNLIDCCEICCNPACFGCLN
What are the official names of this protein?
Heat-stable enterotoxin ST, Non O1-ST, Non-agglutinating cholera vibrios ST, NAG-ST.
What is the protein family that this protein belongs to?
Belongs to the heat-stable enterotoxin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL7_HALHL
Sequence: MAASKDEILESIANMSVMEVVELIEAMEEKFGVTAAAAVAAAPAAGGGGGDEGGAAEEQTEFDVILSSHGDNKVGVIKAVRGVTGLGLKEAKEVVEGCPAPIKEGASKEEADDIKAKLEEAGASVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: RN138_RAT
Sequence: MSEELSADTSYTEDDFYCPVCQEVLKTPVRTAACQHVFCRKCFLTAMRESGIHCPLCRGSVTRRERACPERAIDLENIMRRVSGSCRCCSKKIKFYRMRHHYKSCKKYQDEYGVSSVIPNVKISQDSVRSSNRSETSASDNTETYQEDTSSSGHPTFKCPLCQESNFTRQRLLDHCNSNHLFQIVPVNLQLDEETQYQTAVEESFQVNM
What is the function of this protein?
E3 ubiquitin-protein ligase involved in DNA damage response by promoting DNA resection and homologous recombination.  Recruited to sites of double-strand breaks following DNA damage and specifically promotes double-strand break repair via homologous recombination.  Two different, non-exclusive, mechanisms have been proposed.  According to a report, regulates the choice of double-strand break repair by favoring homologous recombination over non-homologous end joining (NHEJ): acts by mediating ubiquitination of XRCC5/Ku80, leading to remove the Ku complex from DNA breaks, thereby promoting homologous recombination.  According to another report, cooperates with UBE2Ds E2 ubiquitin ligases (UBE2D1, UBE2D2, UBE2D3 or UBE2D4) to promote homologous recombination by mediating ubiquitination of RBBP8/CtIP.  Together with NLK, involved in the ubiquitination and degradation of TCF/LEF.  Also exhibits auto-ubiquitination activity in combination with UBE2K.  May act as a negative regulator in the Wnt/beta-catenin-mediated signaling pathway.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF138, RING finger protein 138, RING-type E3 ubiquitin transferase RNF138.
What are the subcellular locations of this protein?
Chromosome. Note=Recruited at DNA damage sites. Localizes to sites of double-strand break: localization to double-strand break sites is mediated by the zinc fingers.
Protein: EME2_XENTR
Sequence: METKQERETGRSSPDPSPRKLIRRAATWEISDSDNEEETNKPQTESRKGPIVNIEATDQLLGVQKDPAQQPDVEEKTKNLVLPPPTSTTPSPTRRSRKKKTPEQVAAEQEQAEEKKRQRELKRQEKAQKKELEKIERERRKETNLALKLLRPDQCGKYMVVKVDAGLLEDAGSEDVLEALRVAEYNYSIEPHSVPQSISWRREMPADWTCIEGMDMKEEEEDQLLVLVEPKSYLSSVRTYAQAPYYFCVGNEMEEIPGSVFSIPAKNPHKKVTLVIIGLQEYRWCERLSRQIQRQSLDAAEGRDSNKDQSATRATRQQIQEALVFLQLHYNTEVLCLDTWKELGQHVCAVTKSIAQRPFRKHWEAQTFSFCTSAGSWRGWGPRGVLTGLPLTWRRQIQQLNRVSPAMAAVVSQAYPSPQLLMQAYSACGSDRERMSLLTDLRIPQDNNTGVTQKAEDPREVADIAQEGDQVPGRERRIGPDLSRRIWLLMTSKNPELVLDLNS
What is the function of this protein?
Interacts with mus81 to form a DNA structure-specific endonuclease which cleaves substrates such as 3'-flap structures.
What are the official names of this protein?
Probable crossover junction endonuclease EME2.
What is the protein family that this protein belongs to?
Belongs to the EME1/MMS4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FENR_STRP8
Sequence: MKDKAYDITIIGGGPIGLFAAFYAGLRGVTVKIIESLSELGGQPAILYPEKMIYDIPAYPSLTGVELTENLIKQLSRFEDRTTICLKEEVLTFDKVKGGFSIRTNKAEHFSKAIIIACGNGAFAPRTLGLESEENFADHNLFYNVHQLDQFAGQKVVICGGGDSAVDWALALEDIAESVTVVHRRDAFRAHEHSVELLKTSTVNLLTPYVPKALKGIGNLAEKLVIQKVKEDEVLELELDSLIVSFGFSTSNKNLKNWNLDYKRSSITVSPLFQTSQEGIFAIGDAAAYNGKVDLIATGFGEAPTAVNQAINYIYPDRDNRVVHSTSLID
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: KIBRA_DROWI
Sequence: MSNLPQTQAHHLQPHPQHPQHLLHHHQQQQQQQQQQQQQQHGHHNHSDFPLPDGWDIAKDFDGKTYYIDHINKKTTWLDPRDRYTKPQSFEDCVGDELPVGWEEAYEPNIGRYYINHIAQSTQLEDPRQEWKSVQEQMLSDYLSAAQDQLENKREMYDVKQQRLLLAQEEYNHLNKLAASRSSLCSSSSSMSRHDPELLRADLMLARERVRQLKQELNHITNDISHTERGMNTLYSVGEKINARENGCYDIAEVQAIREEMLKVHKSLVSGEKVREELMRSLVQIKNELSRQQMNEENADLLNAASPFDRVCVASQTDLCGAGESLNGGARFAEMAKTKLQYAEWRKHIKKLQQQLADHVERIEPGQLESDKDRILLIQEKEKLLNDLNSISLKSRSLEETQVIQQTRQKLEDDLKEAYEANNTCIANRLRFHEEKQHLLDKLQEALKSTKLLEERLKSFSSESTFSISSGSSLGSLSTASSKSALSFTDIYVDHFAVDSPIDVVDLQRRSQRFFQQQQQQQQHRLPPVHGHPVLQQQQSSEVSLSPRSSLSMETPPASPMKYNAGADQPQLPPAAASLAPPKEEPTYANALPAPPAYTAPPPAPIAAVRAPHAYDLDSTVLDCMILEAKLKKLNLNSPLNLAAPLSPISEKPSLLDLPQEMLSRSSSTSNTRSVSAAVSNESVAGDSGVFEASRAHLPRRELAQVQIGLKYLKQEGVLVVSLERANNLLALWTASSDNSQVYLRAALLPNSLTSIRTKALGDFQKPVFNDTFAVPISLDKLLTKSLQVTVVSMTGQKEEIIGTVQISMAEFNPDDSTLKWYNVLSSKFMPSFESLDIPSTSAAAAAAAVAANNTNAMNSNSNNNREESSDESTITSSQTSTLTRNQAPPLELQAQIAEELPEHVRLNEQECSDDDDDDDDDDDEEEEDEQQLIGTEELTNSSGMLDTYLKIMKQQYADKETNTECAFPPEKSRAQSQLLDDRPVKRSQTFTPSAAVSKSRYNCRLNRSDSDSAMHFGVTPHTFHRGAAERRSLRFHTKAPKTATKLHHTHIPRTSLDLELDLQAQHSKLFFLNDQIAKLQNLKDVLQKGCESKDPLIAAWAIENEEFQRLVARADPAKCPEERQLQKLLMKTAKEIHKLRKTKVPKGCPDLVSFKEKITFFTRKGLSVPELPSEFILADGDAIEEEEEEDDNAAETAIAINTALVASSNRNKNLSEHHHRAACNSGAVPKRSATPTPITAATTADASASSAPATAAVAPTTAATVSDDKPDQQRFDYVVDRNYGVEV
What is the function of this protein?
Regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.  The core of this pathway is composed of a kinase cascade wherein Hippo (Hpo), in complex with its regulatory protein Salvador (Sav), phosphorylates and activates Warts (Wts) in complex with its regulatory protein Mats, which in turn phosphorylates and inactivates the Yorkie (Yki) oncoprotein.  Kibra acts synergistically along with Ex and Mer to regulate the Hippo signaling pathway (By similarity).
What are the official names of this protein?
Protein kibra.
What is the protein family that this protein belongs to?
Belongs to the WWC family. KIBRA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Apical cell membrane. Note=Localizes at the apical cortex of epithelial cells and cytoplasmic, punctate.
Protein: PUR4_XYLFT
Sequence: MIVLKGASALSPFRLARFESRLQTTVPELRIVGAWHCYLIQIKSGHTLDMSALHRILQAESVSELPQKHVVSRYVMPRLGTHSPWSSKTTELLHGADQPIARIERGTRIDLLGWSANAATCPAIAKQLYDPMTQSLLESEDEVKTLFNVPEPRPLERIALIDLEHANTRLGLALTADEIDYLRTRYTELNRVPSDVELMMFAQANSEHCRHKIFNATWTIDDKEQPYSLFQMIKHTHQHTPQYTLSAYADNAAVIEGHPTTRYRPDPITGEYRHEAVLPGAFQIKVETHNHPTAIAPFPGASTGAGGEIRDEGATGRGGKPKAGLSGFSVSHLRIPTLPHPWETPRALNPRMASALDIMLEGPLGSAAFNNEFGRPNLLGYFRSFELSASKTLTRAYDKPIMLAGGLGAIDRIHIKKLRLQPGDVIIVLGGPAMLIGLGGGAASSVTSGTSTEALDFASVQRDNPEMQRRCQEVIDHCVALGTNNPIRSFHDVGAGGLSNAIPELLHDSEVGGVIDLAKIPSDDPSLSPLELWCNESQERYVLGISAPHLQAFAAICSRERCPFAAVGVATATEQLIVGYGVTLPAALHVTEQQTPQRANRTETSPTPNTLVSPVREAFAIDLPMDVLFGKAPKMHRNTAHPPPPQWPTLDSTQLDLHHAGLRVLAHPTVAAKNFLVTIGDRSIGGLTAREQMIGPWQLPLADCAITLAGFSSYAGEAFAIGERAPLALLNSAAAARMAVGEAITNLCAAPVESLSMVKLSANWMAAAEYPGEDALLYDAVKAIGIELCPALDISIPVGKDSLSMQSRWQGDGATHTCISPVSLVISAFTPVADARRQLTPLLHHQTNSELWLIALDGGKQRLGGSVLAQVHADSAALPAFGGECPDLDTPETLRAFFALMNDARNAGLLLAYHDRSDGGAFAALCEMAFASHLGLDITCDNRTEHLFPHLFNEELGAIVQVADEHRTAFADLVEHHGLTAYTQRIAHPTTAPSIRVMHNDQCLAQWTWETLFDAWWSVTHAIQRLRDNPECADEEREIARTFTAPGLKPTLSFDPAADVAMPFISTGIRPKVAILREQGINGHIEMALCFERAGFHSVDIHMNDLITGRVHLDEFVGLAACGGFSYGDVLGAGRGWATSILERTALRDQFAAFFTRTDRFALGVCNGCQMLSQLKSMIPGAEHWPRFVRNRSEQFEARTALLEVIQSPSIFLSGMAGSRLPVAVAHGEGYAMFDTPADQAAAHVALRYINGHGQAATHYPLNPNGSPNGITGLTTTDGRITILMPHPERTPRTINLSWCPNEWGEDAPWLRLFRNARAWVG
What is the function of this protein?
Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase, FGAM synthase, FGAMS, Formylglycinamide ribonucleotide amidotransferase, FGAR amidotransferase, FGAR-AT.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMYP_HUMAN
Sequence: MKFFLLLFTIGFCWAQYSPNTQQGRTSIVHLFEWRWVDIALECERYLAPKGFGGVQVSPPNENVAIYNPFRPWWERYQPVSYKLCTRSGNEDEFRNMVTRCNNVGVRIYVDAVINHMCGNAVSAGTSSTCGSYFNPGSRDFPAVPYSGWDFNDGKCKTGSGDIENYNDATQVRDCRLTGLLDLALEKDYVRSKIAEYMNHLIDIGVAGFRLDASKHMWPGDIKAILDKLHNLNSNWFPAGSKPFIYQEVIDLGGEPIKSSDYFGNGRVTEFKYGAKLGTVIRKWNGEKMSYLKNWGEGWGFVPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKMAVGFMLAHPYGFTRVMSSYRWPRQFQNGNDVNDWVGPPNNNGVIKEVTINPDTTCGNDWVCEHRWRQIRNMVIFRNVVDGQPFTNWYDNGSNQVAFGRGNRGFIVFNNDDWSFSLTLQTGLPAGTYCDVISGDKINGNCTGIKIYVSDDGKAHFSISNSAEDPFIAIHAESKL
What are the official names of this protein?
Pancreatic alpha-amylase, PA, 1,4-alpha-D-glucan glucanohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: MAP2_PUCGT
Sequence: MTIPVPKPAHPAAPDTNTDGLPNPKVVVPVEADEEEDDDDEEGKEDADGAVPAASHFSTHALDGTKKKKKKKKKPKKKKTGEAGAGGQSEPPRVPVSKLFPNGNYPSGEESAYLGENSYRTTSSEKRELERLAAQEDPESAENYNSIRRAAEVHRQVRRYVQQTVKPGMSMTEIAEMVEDGTRALVEVDGLQRGIGFPTGVSLNHCAAHYTPNAGDTIVLSADDVLKVDFGVQIGGRIVDSAFTMTFNNKYDKLLEAVRAATNTGIREAGIDARLSDIGASIQETMESYEVEVDGKVHKVKSIRNLTGHNILPYHIHGGKSVPIVANSDESAIMEEGDHFAVETFGSTGRGYVMDDGECSHYAKNPDVNKPIRLARAKTLLNTINKHFDTLPFCKRYLDRLGESRYYAALDNLVNLGIVQAYPPLSDIQGCMTAQYEHTIILRPTCKEVVSRGDDY
What is the function of this protein?
Cotranslationally removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
What are the official names of this protein?
Methionine aminopeptidase 2, MAP 2, MetAP 2, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_AZOC5
Sequence: MITAPFFTLDRRDLLGIEGLSAPEIVGLLDLAEEFVVLNRQIEKKRSTLRGRTQVNLFFEASTRTQSSFELAGKRLGADVMNMSVGNSSVKKGETLIDTAMTLNAMRPDILVVRHHASGAVALLARKVDCCVVNAGDGAHEHPTQALLDALTIRRNKGRIEGLTVAVCGDVLHSRVARSNILLLHTLGARVRVVAPSTLLPTGIENFGVEVHRSMESGLEGADIVMMLRLQRERMAGSFIPSVKEYFHYYGLDEAKLKRAKPDALVMHPGPMNRGVEIDSAVADGAQSLIREQVEMGVAVRMAVLDALARKLPNATGAERD
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: PDHR_SALTY
Sequence: MAYSKIRQPKLSDVIEQQLEFLILEGTLRPGEKLPPERELAKQFDVSRPSLREAIQRLEAKGLLLRRQGGGTFVQSSLWQSFSDPLVELLSDHPESQFDLLETRHALEGIAAYYAALRSTDEDKDRIRELHHAIELAQESGDLDAESEAVLQYQIAVTEAAHNVVLLHLLRCMEPMLAQNVRQNFELLYARREMLPLVSTHRTRIFEAIMAGKPEEAREASHRHLAFIEEIMLDRSREESRRERALRRLEQRKN
What is the function of this protein?
Transcriptional repressor for the pyruvate dehydrogenase complex genes aceEF and lpd.
What are the official names of this protein?
Pyruvate dehydrogenase complex repressor.