PharMolix/UniProtQA huggingface dataset:
Protein: LIPA_PSEFS
Sequence: MTTDAVQTMIPTLDITERPAPAPRAKVEAGVKLRGAEKVARIPVKIIPTTELPKKPDWIRVRIPVSPEVDRIKALLRKHKLHSVCEEASCPNLGECFSGGTATFMIMGDICTRRCPFCDVGHGRPKPLDVNEPESLAIAIADLKLKYVVITSVDRDDLRDGGAQHFADCIREIRKLSPNVMLETLVPDYRGRMDVALEITAAEPPDVFNHNLETVPRLYKAARPGSDYQWSLTLLQKFKQMMPHIPTKSGLMLGLGETDEEVIEVMKRMREHDIDMLTLGQYLQPSRSHLPVQRFVHPDTFAWFAEEGYKMGFKNVASGPLVRSSYHADEQAKLVKASLVS
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KHSE_PROM5
Sequence: MSIPNLGKKIIVTVPSTTANLGPGFDCLGAALDLYNEFIFTRIEGDGDRFDLIMESTDGNHLRGGPENLVFRAAQKVWESADVSPFALEARVKLAVPPARGLGSSATAIVAGLIGANAIMNSPLPKEKLLELAIDIEGHPDNVVPSLLGGLCLTARSSSQRWRIIRCDWHDSIKAVIAIPAIRLSTSEARRVMPKNIPISDAVTNMGALTLLLNGLKTGNDELIKEGMFDKLHEPYRWKLIKGGLEVKEAALQAGALGCAISGAGPSILALCKSNNGKVVSQAMVKAWENLGIASRAPFLNVQTKGSQFKTISGK
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_KOSOT
Sequence: MRFSQLYAPTLKEAPSDADLVSIKLLIRGGFVRKNAAGVYTYLPLGLRVLKKVEQIVREEMAAIGCQEILMPIIQPAELWFESGRWDDYGPEMMKFKDRHERDFTLGPTHEELLTSIVRNELRSYRQFPLSLFQIANKYRDEIRPRFGLIRAREFLMKDAYSFHTDWESLDKAYKDFYKAYGRIMERIGLKYLVVEADTGAIGGDESHEFNALADTGESTLLYCDCGYAASDEKAEYMMLSDEDPDVQEEKALELVETPGVRTVQEVADFLKVTPEQIVKSLLYRGKEGFVMALIRGDQELNESKLKAHLKDQTLTMATLEEVLENFGVPIGFIGPVGMNDKVKIVADFTVKPLRNFVVGGMKEGYHYKGVCLGRDFSVDEWFDLKLAVEGDPCPKCGKPMKMTKGIELGHIFKLGTKYSEKMNGYFTDENGENHPYIMGCYGWGISRTMSAVVEQMHDEHGMIWPLSIAPFHIIITMVNPSQEQISKVGEELYELLKEKYEVLLDDRQASPGVKFKDADLIGIPLRITVGKKLTKGLIELKLRTEKQLVEVSISEGYDSVLETVEKLLKKYDPAKVAEVD
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUC_AERS4
Sequence: MAKTLYQKVFDAHVVREVDGETPLIYIDRHLVHEVTSPQAFDGLRAMNRPLRRPDLTWATMDHNVSTTTKDIAASGEMARIQMETLADNCKEFGVRLYDLNHKYQGIVHVMGPELGITLPGTTIVCGDSHTATHGAFGSLAFGIGTSEVEHVMATQTLKQGRAKTMRISVNGKLAEGISAKDVVLAIIGQVGHAGGTGYVVEFAGEAIAGLSMEGRMTVCNMAIELGAKAGMIAPDQTTIDYIRGKEFAPKGESLDQAIAYWLSLKSDQGAHFDAEVILDAADIAPQVTWGTNPGQVIAVNEPIPAPESFSDLMEQQSARKALAYMDLQPGQKLTDVAIDKVFIGSCTNSRIEDLRAAAAIARGRKVAAGVQALVVPGSEQVKAQAEAEGLDKIFLEAGFEWRLPGCSMCLAMNNDRLQPGERCASTSNRNFEGRQGRAGRTHLVSPAMAAAAAVTGRFADIRAL
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: MDM34_PARBP
Sequence: MAFNFNWSPLMADAGFYTRAQDLLTAALNKSPKPPIIVDDIVVTELNLGSNPPELEILEIGDLAEDRFRGIFKMSYAGDAVLTLKTCVQANPLNTYLLTRHPFTSPQPLAAATGLTIPLQITLSDIKLSGFVILVFSKQKGITVVFRNDPLESLKVSSTFDSIPFVRDYLQKEIEGQLRILFMDELPAIIHRLSLRLWSTEYSELETTCDQVTNPSLEGPGQDPLLNPPQDPVDSFGNVLSTSEIASLSLDSGVEMHSLFSRKNALRIAALTDSQRTLSLFTPSIREVVFRAWTGSIEQADGPSGLVSPMSPPLSRTQSHITVASAPLSSQDTASVASSQSRPGLPSSGYSGYGLSLGAARHSKAHACKRKKRVIDLRPHRKPTDDIASISGESSCTDSTITTTTKSAASVYSSSIIPEENNDDDPVTPPVSPVRNSTVRRRQTLRDRIVDRDDAERTNIRRPPIPAEFGHEFPLRPTQPLPSNEIDRNVTSPNPKPEDSHHFQPPRQDTAPIRNIPSAPLGPPAQAPIPASASASASAYPPEKPTYTQSFPPSFMEVAQNGSILEQAWMMKMASEIARRIQDENSSAMGSYVGSGSGSGGFWDRSHTPPPAYRH
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 34.
What is the protein family that this protein belongs to?
Belongs to the MDM34 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria- endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: MURB_THIDA
Sequence: MRHDYRMSEVEVAGGTAPVLRGRFLYNEPMSRHVSWRAGGSARRLYVPADLEDLVWLVRSVPADEAIHMVGLGSNLLVRDGGVAGVVILLHGVLTKLALESRTHGLPPAPPARDTAVVYAQAGVASPKLARFAATHGLVGGEFLAGIPGTVGGAIAMNAGCYGSETWDTLVQLHTLDRQGQLNERLPEEYVTGYRHAALKRPHEEWFIGGWFRLERGDGAASRERIRSLLKTRIASQPLNLPNAGSVFRNPPGDFAARLIEACGLKGHRIGDAQVSTKHANFIVNVGKATATDIERLIEHVEDSVEARTNVRLMREVRIIGERQ
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPIA_XANC5
Sequence: MSEAKRLAAEKAIDYVEDGMIVGVGTGSTVAYFIDALGRIGHRIKGAVSSSEQSTARLRQHGVEVLDLNHTGNLSLYVDGADECDPNRCLIKGGGAALTREKIIAEASERFICIVDPSKQVPVLGKFPLPVEVIPMARSLVARQILALTGGQPVWRDGVVTDNGNVVLDVHHLQITDPVGLERSLNQIPGVVCVGLFARRPADVVIVGGEPPQVI
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: MSRA_PHOLL
Sequence: MPTSANKSLSIDPHSALPGRTEPLKVSPNHAVTDHTIEPVPENMEVAYFGMGCFWGVERLFWQQPDIYTTSAGYSGGTTANPTYEEICSGLTGHAEVVRIVYDPAKNSYENLLKLFWENHDPAQGMRQGGDIGSQYRSAIYTVSPQQHELALASREHFQKAMQQQSDNRPITTEITEAGPFYFAEDYHQQYLFKNPEGYCGLGGIGVCLPKMNEN
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: BORC7_XENTR
Sequence: MTASTEGQARYGQSVKGLLTEKVSTCGADVIALTKQVLKGSHSSELLGQAARNMVMQEDSILHSEDSLRKMAIITTHLQYQQEAIQKNVEQSSNLQDQLKHLLK
What is the function of this protein?
As part of a BORC-like complex may play a role in lysosomes movement and localization at the cell periphery.  Associated with the cytosolic face of lysosomes, this complex may couple lysosomes to microtubule plus-end-directed kinesin motor.
What are the official names of this protein?
BLOC-1-related complex subunit 7.
What is the protein family that this protein belongs to?
Belongs to the BORCS7 family.
What are the subcellular locations of this protein?
Lysosome membrane.
Protein: RL25_PSEA7
Sequence: MVDFILNAQVRSDLGKGASRRLRRNAAQVPAVIYGGDKEPQSVTLELREIAKLLENEAAFSHVIALNVGGAKETVLIKALQRHPAKGFVMHADFLRVVADHKLTAHVPLHFINEDVAVGVKQAGGEISHTISEVEVSCLPKDLPEFIEVDMAKVELGQIVHLSDLKAPKGVELVQLAHGNDLAVANIHASRVVKEEGSEEGAAE
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: NAGB_SALNS
Sequence: MRLIPLSTAEQVGKWAARHIVNRINAFKPTADRPFVLGLPTGGTPLTAYKALVEMHKAGEVSFKHVVTFNMDEYVGLPKEHPESYHSFMHRNFFDHVDIPAENINLLNGNAPDIDAECRQYEEKIRSYGKIHLFMGGVGNDGHIAFNEPASSLASRTRIKTLTHDTRVANSRFFDGDVNQVPKYALTVGVGTLLDAEEVMILVLGHQKAQALQAAVEGNVNHMWTISCLQLHPKAVVVCDEPSTMELKVKTLKYFNELEAENIKGL
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: MTF1A_MOUSE
Sequence: MASRNIWCVRRNFLFDLRDWMLQYSAEVFLKSISFRPFSAECDSKDKESLEEEREDLLSNLVTMGVDIDMARRRQPGVFNKAVTNEQELKLFLLSKGASDKVIGSIISRYPRAITRTPESLSKRWDLWRKIMASDLEIVNILERSPESFFRSNNNLNLENNIKFLCSVGLTHKCLCRLLTNAPRTFSNSLNLNKQMVEFLQETGMSLGHNDPRDFVRKIISKNPSILIQSTKRVKTNIEFLQSTFNLNKRDLLLLICGPGARILDLSNDCTKKNYTNIRERLLSLGCSEEEVQRFVLSYLNMVFLSEKKFNDKIDCLIEEKISASQIIENPRILDSSINTLKTRIRELSHAGYDLSTSSIALLSWSQRRYEAKLKRLCG
What is the function of this protein?
Transcription termination factor.  Binds to a 28 bp region within the tRNA(Leu(uur)) gene at a position immediately adjacent to and downstream of the 16S rRNA gene; this region comprises a tridecamer sequence critical for directing accurate termination.  Binds DNA along the major grove and promotes DNA bending and partial unwinding.  Promotes base flipping.  Transcription termination activity appears to be polarized with highest specificity for transcripts initiated on the light strand.
What are the official names of this protein?
Transcription termination factor 1a, mitochondrial, Mitochondrial transcription termination factor 1a, mTERF1a.
What is the protein family that this protein belongs to?
Belongs to the mTERF family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: BIOH_SHIBS
Sequence: MNNIWWQTKGQGNVHLVLLHGWGLNAEVWRCIDEELSSHFTLHLVDLPGFGRSQGFGALSLADMAEAVLQQAPDKAIWLGWSLGGLVASQIALTHPERVQALVTVASSPCFSARDDWPGIKPDVLAGFQQQLSDDFQRTVERFLALQTMGTETARQDARALKKTVLALPMPEVDVLNGGLEILKTVDLRQPLQNVPMPFLRLYGYLDGLVPRKVVPMLDKLWPRSKSYIFAKAAHAPFISHPVEFCHLLVALKQRL
What is the function of this protein?
The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete.  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.
What are the official names of this protein?
Pimeloyl-[acyl-carrier protein] methyl ester esterase, Biotin synthesis protein BioH, Carboxylesterase BioH.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3MGH_CHLFF
Sequence: MLPESFFLNDDVLYLAKELLGHSLVTQIEGKTTSGIIIETEAYRGPDDKACHAYNYRKTQRNLPMYSRGGIAYIYQCYGMHALFNVVTGSQNLPHAVLIRAIAPQKGEDIMIQRRQWQNKPKHLLTNGPGKVCQALNLTLEHNTQSLTSPQIHISQKKISGTITQTPRIGIDYAEEYRDLPWRFLLNIKKSKKI
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: ISPE_YERPA
Sequence: MTTANQPICPSPAKWPSPAKLNLFLYITGQRADGYHQLQTLFQFLDYGDQLTIEPRDDNQIRLLTPIAGVENEQNLIVRAAKMLQKHPGNTPVPRGADISIDKCLPMGGGLGGGSSNAATVLVALNLLWQCGLTDEQLADLGLTLGADVPVFVRGHAAFAEGIGEKLQPAEPVEKWYLVIHPGVNIPTPIIFSDPELKRNTPIRPLAALLSTPYANDCEPIARKRFREVEQALSWLLEYAPSRLTGTGACVFAEFDTESSARQVLSIAPEWLHGFVARGVNVSPLHRVRSGKIESSERR
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: ELF4_HUMAN
Sequence: MAITLQPSDLIFEFASNGMDDDIHQLEDPSVFPAVIVEQVPYPDLLHLYSGLELDDVHNGIITDGTLCMTQDQILEGSFLLTDDNEATSHTMSTAEVLLNMESPSDILDEKQIFSTSEMLPDSDPAPAVTLPNYLFPASEPDALNRAGDTSDQEGHSLEEKASREESAKKTGKSKKRIRKTKGNRSTSPVTDPSIPIRKKSKDGKGSTIYLWEFLLALLQDRNTCPKYIKWTQREKGIFKLVDSKAVSKLWGKQKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKEMPKDLVVIEDEDESSEATAAPPQASTASVASASTTRRTSSRVSSRSAPQGKGSSSWEKPKIQHVGLQPSASLELGPSLDEEIPTTSTMLVSPAEGQVKLTKAVSASSVPSNIHLGVAPVGSGSALTLQTIPLTTVLTNGPPASTTAPTQLVLQSVPAASTFKDTFTLQASFPLNASFQDSQVAAPGAPLILSGLPQLLAGANRPTNPAPPTVTGAGPAGPSSQPPGTVIAAFIRTSGTTAAPRVKEGPLRSSSYVQGMVTGAPMEGLLVPEETLRELLRDQAHLQPLPTQVVSRGSHNPSLLGNQTLSPPSRPTVGLTPVAELELSSGSGSLLMAEPSVTTSGSLLTRSPTPAPFSPFNPTSLIKMEPHDI
What is the function of this protein?
Transcriptional activator that binds to DNA sequences containing the consensus 5'-WGGA-3'.  Transactivates promoters of the hematopoietic growth factor genes CSF2, IL3, IL8, and of the bovine lysozyme gene.  Acts synergistically with RUNX1 to transactivate the IL3 promoter (By similarity).  Transactivates the PRF1 promoter in natural killer (NK) cells and CD8+ T cells (PubMed:34326534).  Plays a role in the development and function of NK and NK T-cells and in innate immunity.  Controls the proliferation and homing of CD8+ T-cells via the Kruppel-like factors KLF4 and KLF2 (By similarity).  Controls cell senescence in a p53-dependent manner.  Can also promote cellular transformation through inhibition of the p16 pathway.  Is a transcriptional regulator of inflammation, controlling T-helper 17 (Th17) cells and macrophage inflammatory responses.  Required for sustained transcription of anti-inflammatory genes, including IL1RN (PubMed:34326534, PubMed:35266071).  Is a negative regulator of pro-inflammatory cytokines expression including IL17A, IL1B, IL6, TNFA and CXCL1 (PubMed:34326534, PubMed:35266071).  Down-regulates expression of TREM1, a cell surface receptor involved in the amplification of inflammatory responses (By similarity) (PubMed:34326534, PubMed:35266071).
What are the official names of this protein?
ETS-related transcription factor Elf-4, E74-like factor 4, Myeloid Elf-1-like factor.
What is the protein family that this protein belongs to?
Belongs to the ETS family.
What are the subcellular locations of this protein?
Nucleus, PML body. Note=Accumulation into PML nuclear bodies is mediated by PML.
Protein: FOLD_PETMO
Sequence: MLIEVDNIIDEIKAEISSLKEKVPYEPKLVSLVVEPDESTKSYLNSQKRNAKKFGINLEIVESNDLTNDLRKYNEDDDTDAIFIARPLKKGYTELDIAKYINPEKDVEGVSLHNIGSMFYEKELFVPCTAEAVVKIIEDTTDVRGKNIVILGRSTTVGKPAAIMLQRHGRDATVTVTHTKTKNLKEITKEADILVAAIGKANFVDSTFVKEGMIVIDVGINVVDGKIVGDVNKDVSEICQLTPVPGGVGSVTTAILMRNVFRAANNKKGDMQL
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: SYY_XANCP
Sequence: MATIDESLALIGRGAEEILKLEQLEARLTSGVPLRVKAGFDPTAPDLHLGHTVLLNKMRQFQELGHQVIFLIGDFTGMIGDPSGKNVTRKPLSREDVLANARTYEEQVFKILDRTRTEVRFNSEWFGQMSAADMIKLSAQHTVARMLERDDFAKRFAGQQPIAIHEFLYPLVQGYDSVALKADVELGGTDQTFNLLMGRGLQEHYGQAPQVVLTMPLLEGLDGVAKMSKSLGNYIGINEPAIDIVTKTMKIGDTLTWRWIDLLSFDISVAEAARFKEDVAAGNLHPRDVKLRLARELATRFHDAATAEQAIAGWHAVVTGQGDTSVLPLQQVSVPAEGLRIASLLTAAGLTPSNSEATRKLKERAVKIDGEVVDDLARQFGPGFEGVIQVGKRNFARVALVTS
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NHAA_BIFAA
Sequence: MMATSKRGTWATIRRIAASDRISGLIMLGFALAGLLLANLPFTAHAFEQLENFHIAIPHTNIDMGLGHWVQDGLLTVFFLTVGLELKQELTTGSLSNPKAAAVPMLCAVGGMLAPPVLFIGVISLFAAAGSGQLVIASGTSFSFAQMSNGWAVPTATDIAFSLAVLALFAKALPGSIRAFLMTLATVDDLLAIILIAVFFSSVNAWYWFLGIAVCAVVWYFLVRMRKVPWLAVAIVGVLAWVMMFEAGVHPTLAGVLVGLLTPAHERFGEKTPRAERYADKLQPFSALLALPIFALFATGVHFESLTLALFVSPVVVAVMVALVVGKPLGIMTTAWLSTHVGGLKMAKGLRVRDMFPAACACGIGFTVSFLIASLAYQDAELSAEARFGVLVGSMVAAVISGILLSRQSKRFELEDGTKHKHHTGDEDAMNEVETVLEDGTVVVSQIIGTHQEQ
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CREE_STRCM
Sequence: MSVRRLTVCIVGAGPRGLSVLERFCAHERKSASHPAVTVHVVDPARPGAGRVWRTGQPRQLLMNTVASQVTVFTDGSVDMAGPVEAGPSLHEWARELAALTPVEELLGGHDDATLAEARALGADSYPTRAFYGCYLEEMFRRVVCGAPAHLEVRVHRSTAVSLADETPGSGGAQSLLLADGTRLAGLDAVVLALGHVRAEEPGAPDPRAAALGLAHFPPANPADLDLSGIAPGTPVLLRGLGLNFFDHMALFTLGRGGAFSRRPHGLRYHPSGLEPRLYAGSRRGVPYHARGENEKGVDGRHTPLLLTPERIAELTGRHREGPGLSFLRTLWPLIAREVECVYYGTLLASRGRAAERDAFVTAYLAGGDDTDRGGVLERFGIGPADRWCWERTASPHPRHGFTGPDGHRRWLLEHLAQDVRRARAGNVSDPHKAALDVLRDLRNEIRLVVDHGGLDGLSHRDDLDGWYTGLNAFLSIGPPASRIEEMAALIEAGVLDVVGPGLEVDIDEADAAFVARSPLVPGRPVRAHVLIEARLPVTDLRRTADPLLRDLLRSGQCRSYRIPAGRAPEGYETGGLEVTRRPYRLVDALGRAHPRRFAFGVPTEAVHWVTAAGARPGVNSVTLGDADAIAHAVASLTPAAAPRLPAYEDPGVRCPSDDRLTEVTA
What is the function of this protein?
Part of a gene cluster involved in the biosynthesis of cremeomycin, a light-sensitive o-diazoquinone with antibacterial and antiproliferative effects (PubMed:26278892, PubMed:26689788).  Catalyzes the iterative oxidation of L-aspartic acid to nitrosuccinic acid (2-nitrobutanedioate) via N-hydroxyaspartic acid and nitrososuccinic acid (PubMed:26689788).
What are the official names of this protein?
L-aspartate N-monooxygenase (nitrosuccinate-forming), Nitrosuccinic acid synthase.
Protein: RSMB_SCHPO
Sequence: MGTTKMVSLLNHSLNVTTKDGRTFVGQLLAFDGFMNLVLSDCQEYRHIKKQNVPSNSVYEEKRMLGLVILRGEFIVSLSVQGPPPMDPSMRGSLLSGPGVARPAGRGIPLGQAPVGLAGPVRGVGYTAPPPPAGFGRGAPPPGFRPV
What is the function of this protein?
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (By similarity).
What are the official names of this protein?
Small nuclear ribonucleoprotein-associated protein B, snRNP-B, Sm protein B, Sm-B, SmB.
What is the protein family that this protein belongs to?
Belongs to the snRNP SmB/SmN family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Localizes to the nucleus predominantly.
Protein: CAPZA_YEAST
Sequence: MSSSKFEEVINKIINDSPPGELREVYDDLIKITSENSKNTILDAIENYNVQNCIPIEVNGNSVIISKYNKEGAKFFDPVNSVIFSVNHLERKGLDIEPYEFTHAKIEKGQLKELHDKLHEYLLQSFPGDVSFAVYPVPEEISKISIIIVSTKYNPNNFWNGHWRSSYIYDLETRELSGQISTQVHYYEDGNVSFQSGKDINQSNVDDVVCTIRDIETNFENDLDLSFFDLNEKQFKALRRRLPVTRSKINWGSAIGSYRLGKNAAEGK
What is the function of this protein?
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends.  Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
What are the official names of this protein?
F-actin-capping protein subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the F-actin-capping protein alpha subunit family.
Protein: PPBN_MOUSE
Sequence: MWGACLLLLGLSLQVCPSVIPVEEENPAFWNRKAAEALDAAKKLKPIQTSAKNLVILMGDGMGVSTVTATRILKGQQQGHLGPETQLAMDRFPHMALSKTYNTDKQIPDSAGTGTAFLCGVKTNMKVIGLSAAARFNQCNTTWGNEVVSVMHRAKKAGKSVGVVTTTSVQHASPAGTYAHTVNRGWYSDAQMPASALQDGCKDISTQLISNMDIDVILGGGRKFMFPKGTPDQEYPTDTKQAGTRLDGRNLVQEWLAKHQGARYVWNRSELIQASLNRSVTHLMGLFEPNDMKYEIHRDPAQDPSLAEMTEVAVRMLSRNPKGFYLFVEGGRIDHGHHETVAYRALTEAVMFDSAVDKADKLTSEQDTMILVTADHSHVFSFGGYTQRGASIFGLAPFKAEDGKSFTSILYGNGPGYKLHNGARADVTEEESSNPTYQQQAAVPLSSETHSGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAACLEPYTDCGLASPAGQSSAVSPGYMSTLLCLLAGKMLMLMAAAEP
What is the function of this protein?
Alkaline phosphatase that can hydrolyze various phosphate compounds.
What are the official names of this protein?
Alkaline phosphatase, germ cell type, Alkaline phosphatase 5, Alkaline phosphatase, placental-like, Embryonic alkaline phosphatase, EAP, Embryonic-type alkaline phosphatase.
What is the protein family that this protein belongs to?
Belongs to the alkaline phosphatase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: PETG_PINTH
Sequence: MIEALPSGIVLGLIPITLAGLFVTAYSQYRRGDQLDI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.