PharMolix/UniProtQA huggingface dataset:
Protein: VOPS_VIBPA
Sequence: MISFGNVSALQAAMPQARNEILNEGKLSIGGKEYTINAATQEFTRANPTSGAVARFFEATGKLFREGSTQSVAKAITKAVFDNEQGQAQRLQTSSSVEHGQMLFKDANLKTPSDVLNAFAKLDSKMVKSHAAELSQLAERAMTEVMLETDSGKNLKALIGDDAVKSLAVRVVKDYGGGVAAAQKNPEVRINQMQAVFDMEVMHLKAAQRHIEGLASTDLNQGVYAEGLPEDAFNKAGVTNNVERAAAWIINASNSKGNDAENITSLLKEYATNGKDLLNMDNLKELHARLVPNVERDYRGPNISGGTLPSSIGGEGMLKQHIEGFLKENPVADKDLGKHLFAGVIGYHGFTDGNGRMGRMLYAIAELRNDSFNPLAMNAENSLHGIK
What is the function of this protein?
Adenylyltransferase involved in virulence by mediating the addition of adenosine 5'-monophosphate (AMP) to specific threonine residue of host Rho GTPases RhoA, Rac and Cdc42.  The resulting AMPylation prevents the interaction of Rho GTPases with downstream effectors, thereby inhibiting actin assembly in infected cells.
What are the official names of this protein?
Protein adenylyltransferase VopS, AMPylator VopS, Vibrio outer protein S.
What are the subcellular locations of this protein?
Secreted. Note=Translocated into the host cell via the type III secretion system (TTSS).
Protein: MYRB_MICGR
Sequence: MSSIRRRHAAASLDTPAVGGRHELGQNFLVDRGVCTRIAEVVSSTTAHPVLELGAGDGAITRALVAANLPVTALELDPRRVRRLQRTFADGVTVVHGDMLRYDFGPYPHHVVSTVPFSITTPLLRRLIGQRFWHTAVLLVQWEVARKRAGVGGTTMLTAASWPWYEFTLVERVPKTSFDPVPSVDGGILVIERRSAPLLDDRCVGDYQNLVREVYTGPGRGLAAILRTRLPGREVDAWLRRERVDPAALPRDLKAGHWASLYRLYREVGTRPAPAGRSVRARPGSVGPDRSLPPRGLRSGPPRARRRGGGA
What is the function of this protein?
Confers resistance to macrolide, lincosamide and streptogramin B antibiotics.
What are the official names of this protein?
Mycinamicin-resistance protein MyrB.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
Protein: ATRF2_STAAC
Sequence: MTEKEKMLAEKWYDANFDQYLINERARAKDICFELNHTRPSATNKRKELIDQLFQTTTDNVSISIPFDTDYGWNVKLGKNVYVNTNCYFMDGGQITIGDNVFIGPNCGFYTATHPLNFHHRNEGFEKAGPIHIGSNTWFGGHVAVLPGVTIGEGSVIGAGSVVTKDIPPHSLAVGNPCKVVRKIDNDLPSETLNDETIK
What are the official names of this protein?
Putative acetyltransferase SACOL2570.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: LHY_ARATH
Sequence: MDTNTSGEELLAKARKPYTITKQRERWTEDEHERFLEALRLYGRAWQRIEEHIGTKTAVQIRSHAQKFFTKLEKEAEVKGIPVCQALDIEIPPPRPKRKPNTPYPRKPGNNGTSSSQVSSAKDAKLVSSASSSQLNQAFLDLEKMPFSEKTSTGKENQDENCSGVSTVNKYPLPTKQVSGDIETSKTSTVDNAVQDVPKKNKDKDGNDGTTVHSMQNYPWHFHADIVNGNIAKCPQNHPSGMVSQDFMFHPMREETHGHANLQATTASATTTASHQAFPACHSQDDYRSFLQISSTFSNLIMSTLLQNPAAHAAATFAASVWPYASVGNSGDSSTPMSSSPPSITAIAAATVAAATAWWASHGLLPVCAPAPITCVPFSTVAVPTPAMTEMDTVENTQPFEKQNTALQDQNLASKSPASSSDDSDETGVTKLNADSKTNDDKIEEVVVTAAVHDSNTAQKKNLVDRSSCGSNTPSGSDAETDALDKMEKDKEDVKETDENQPDVIELNNRKIKMRDNNSNNNATTDSWKEVSEEGRIAFQALFARERLPQSFSPPQVAENVNRKQSDTSMPLAPNFKSQDSCAADQEGVVMIGVGTCKSLKTRQTGFKPYKRCSMEVKESQVGNINNQSDEKVCKRLRLEGEAST
What is the function of this protein?
Transcription factor involved in the circadian clock.  Binds to the promoter region of APRR1/TOC1 and TCP21/CHE to repress their transcription.  Represses both CCA1 and itself.  May recognize the promoter of JMJ14 to regulates its expression during the night in a circadian manner (PubMed:31429787).
What are the official names of this protein?
Protein LHY, MYB-related transcription factor LHY, Protein LATE ELONGATED HYPOCOTYL.
What are the subcellular locations of this protein?
Nucleus.
Protein: MIAB_FRACC
Sequence: MNGRSYEVRTFGCQMNVHDSERLCGLLESAGYSPVDPGGEADVVVFNTCAVRENADNRLYGNLGQLVPVKKGHPGMQIAVGGCLAQKDRAAILDRAPWVDVVFGTHNLHRLPVLLERARHNAAAQVEIAEALEVFPSSLPTRRASHHSAWVSISVGCDNTCTFCIVPSLRGRERDRRPGDVLAEVEALVAEGALEITLLGQNVNSYGRSLGDPGAFAKLLAACGRVDGLERVRFTSPHPRDFTDDVIEAMATTSNVCHQLHMPLQSGSDTVLRRMRRSYRRDRFLGIVERVRAAMPDAAITTDIIVGFPGETEADFADTLDVVRAARFSGAFTFQYSPRPGTPAATMDAQVDRATVADRYTRLVALQDEISWAENRALVGRRVEVLVSEGEGRKDGATGRMSGRARDGRLVHFRADEAASSSTGSGPRAGGAAPAVAVAVAPTVRPGDVVETVVTRAAPHHLTADGPLRSHRATRAGDAWALGRDGDGGGAAAAQQPADGRPIVTLGIPSLRPSSPDPVGPASADAASAGADACCTPVRR
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRAAH_CORGL
Sequence: MTQSAPEFIATADLVDIIGDNAQSCDTQFQNLGGATEFHGIITTVKCFQDNALLKSILSEDNPGGVLVIDGDASVHTALVGDIIAGLGKDHGWSGVIVNGAIRDSAVIGTMTFGCKALGTNPRKSTKTGSGERDVVVSIGGIDFIPGHYVYADSDGIIVTEAPIKQ
What is the function of this protein?
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.  Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
What are the official names of this protein?
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase, HMG aldolase, Oxaloacetate decarboxylase, OAA decarboxylase, Regulator of ribonuclease activity homolog, RraA-like protein.
What is the protein family that this protein belongs to?
Belongs to the class II aldolase/RraA-like family.
Protein: EAMB_ECO24
Sequence: MTPTLLSAFWTYTLITAMTPGPNNILALSSATSHGFRQSTRVLAGMSLGFLIVMLLCAGISFSLAVIDPAAVHLLSWAGAAYIVWLAWKIATSPTKEDGLQAKPISFWASFALQFVNVKIILYGVTALSTFVLPQTQALSWVVGVSVLLAMIGTFGNVCWALAGHLFQRLFRQYGRQLNIVLALLLIYCAVRIFY
What is the function of this protein?
Exporter of O-acetylserine (OAS) and cysteine.
What are the official names of this protein?
Cysteine/O-acetylserine efflux protein.
What is the protein family that this protein belongs to?
Belongs to the Rht family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ZFPL1_AEDAE
Sequence: MGLCKCPKRQVTTQFCFEHRVNVCENCMVVNHTKCTVQSYIQWLKDSDFDSSCPLCGSPLDNEDCVRLICYHVFHWKCLNAKQQSLPANTAPGGHTCPTCSDPIFPPVNLVSPVADVLRTRLGQVNWARNVLELPLLSEDKPDYYTTATTSAGVHNGNTFASSMSQTRSNERPESPHSIVNMESYVSNASPALDFHASSRRPLLARESPIGASDRDDNKYKRRTPQEIFSRWSRRLYAPSSKPPWRRTWFLVLGGCIGFVCIIYVLATLGRRGGDGEVGLIYNRNLPHEE
What are the official names of this protein?
Zinc finger protein-like 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the ZFPL1 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PGP_BOVIN
Sequence: MAEAEAGGDDGRCVRLNAERAQALLADVDTLLFDCDGVLWRGETAVPGAPETLTALRARGKRLAFITNNSSKTREAYAEKLRCLGFGAPAGPDAGREVFGTAYCTALYLRQRLTGPPAPKAYVLGSVALAAELEAVGVSCVGVGPEPLLGDGPGAWLDAPLEPDVRAVVVGFDPHFSYMKLTKAVRYLQQPDCLLVGTNMDNRLPLENGRFIAGTGCLVRAVEMAAQRQADIIGKPSRFIFDCVSQEYGIHPERTVMVGDRLDTDILLGVTCGLKTILTLTGVSSLRDVKSNQESDCMAKKKMVPDFYVDSIADLLPALQG
What is the function of this protein?
Glycerol-3-phosphate phosphatase hydrolyzing glycerol-3-phosphate into glycerol.  Thereby, regulates the cellular levels of glycerol-3-phosphate a metabolic intermediate of glucose, lipid and energy metabolism.  Was also shown to have a 2-phosphoglycolate phosphatase activity and a tyrosine-protein phosphatase activity.  However, their physiological relevance is unclear.  In vitro, has also a phosphatase activity toward ADP, ATP, GDP and GTP.
What are the official names of this protein?
Glycerol-3-phosphate phosphatase, G3PP, Aspartate-based ubiquitous Mg(2+)-dependent phosphatase, AUM, Phosphoglycolate phosphatase, PGP.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
Protein: ROM1_RAT
Sequence: MAPVLPVVLPLQPRIRLAQGTWLLSWLLALAGGLTLLCSGHLLVQLWHLGTFLAPSCSFPALPQTALAAGAVALGTGLGGAGASRASLDAAQYPPWRGVLTPLLVVGTAAGGGLLTLGLGLALALPVSLHQGLEEGLQAALAHYKDTEVPGHCQAKRLMDELQLRYHCCGRHGYKDWFGVQWVSSRYLDPNDQDVVDRIQSNVEGLYLIDGVPFSCCNPHSPRPCLQSQLSDPYAHPLFDPRQPNLNLWAQGCHEVLVGHLQGLSGTLGSILAVTLLLQVLVLLGLRYLQTALEGLGGVIDGEGETQGYLLPGGLKDILQTAWLQGGLAHKPAPEEAPPDEEPPKEVLAEA
What is the function of this protein?
Plays a role in rod outer segment (ROS) morphogenesis (By similarity).  May play a role with PRPH2 in the maintenance of the structure of ROS curved disks (By similarity).  Plays a role in the organization of the ROS and maintenance of ROS disk diameter (By similarity).  Involved in the maintenance of the retina outer nuclear layer (By similarity).
What are the official names of this protein?
Rod outer segment membrane protein 1, ROSP1.
What is the protein family that this protein belongs to?
Belongs to the PRPH2/ROM1 family.
What are the subcellular locations of this protein?
Photoreceptor inner segment membrane; Multi-pass membrane protein. Photoreceptor outer segment membrane; Multi-pass membrane protein.
Protein: TRMD_ECO8A
Sequence: MWIGIISLFPEMFRAITDYGVTGRAVKNGLLSIQSWSPRDFTHDRHRTVDDRPYGGGPGMLMMVQPLRDAIHAAKAAAGEGAKVIYLSPQGRKLDQAGVSELATNQKLILVCGRYEGIDERVIQTEIDEEWSIGDYVLSGGELPAMTLIDSVSRFIPGVLGHEASATEDSFAEGLLDCPHYTRPEVLEGMEVPPVLLSGNHAEIRRWRLKQSLGRTWLRRPELLENLALTEEQARLLAEFKTEHAQQQHKHDGMA
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPG_PSE14
Sequence: MHGESPIKRRESRKIWVGSVPVGGDAPIAVQSMTNSDTNDVAATVAQINRLEAAGVDIVRVSVPDMDAAEAFGRIKQLVKVPLVADIHFDYRIALRVAELGVDCLRINPGNIGREDRVRAVVDAARDRGIPIRIGVNAGSLEKDLQKKYGEPTPEALVESALRHVEHLERLNFQDFKVSVKASDVFMAVAAYRLLAKQIVQPLHLGITEAGGLRSGTVKSAVGLGMLLAEGIGDTIRISLAADPVEEVKVGYDILKSLRLRSRGINFIACPSCSRQNFDVVKTMNELEGRLEDLLVPLDVAVIGCVVNGPGEAKEAHIGLTGGTPNLIYIDGKPAQKLTNDNLVDELERLIREKAAEKAEADASVIVRG
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: NUOB_PSEPG
Sequence: MQYNLTRIDPDAPNEQYPVGERETVTDQLLEDQVHKNIYMGKLEDVLRGAVNWGRKNSLWPYNFGLSCCYVEMTTAFTAPHDIARFGAEVIRASPRQADFMVIAGTCFVKMAPIIQRLYEQMLEPKWVISMGSCANSGGMYDIYSVVQGVDKFLPVDVYVPGCPPRPEAFLQGLMLLQESIGQERRPLSWVVGDQGIYRAEMPAQKDLRREQRIAVTNLRSPDEV
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PSAE_YERPE
Sequence: MSHCVVLNKLESVLIIGDSRYALSKNEVLLLECLYLRAGDVISHDELLTTCWPDRVVSPTSLPVAIKHIRDVFRKITRSEVIKTYKNEGYSYQKDSVLIIIDDGSTEKESHSAAYTRKEKPDIPIKLVGLQILSHLNSTFFIAIMMVIIIIFFMVGGNDIVSFIDSDTNSVIITNVTTKMNGPTAGLPKVKNSMIFKDDFGLVIICDQSECKQQ
What is the function of this protein?
Required for expression of pH 6 antigen.
What are the official names of this protein?
Protein PsaE.
Protein: FPVA_PSEAE
Sequence: MPAPHGLSPLSKAFLMRRAFQRRILPHSLAMALSLPLAGYVQAQEVEFDIPPQALGSALQEFGRQADIQVLYRPEEVRNKRSSAIKGKLEPNQAITELLRGTGASVDFQGNAITISVAEAADSSVDLGATMITSNQLGTITEDSGSYTPGTIATATRLVLTPRETPQSITVVTRQNMDDFGLNNIDDVMRHTPGITVSAYDTDRNNYYARGFSINNFQYDGIPSTARNVGYSAGNTLSDMAIYDRVEVLKGATGLLTGAGSLGATINLIRKKPTHEFKGHVELGAGSWDNYRSELDVSGPLTESGNVRGRAVAAYQDKHSFMDHYERKTSVYYGILEFDLNPDTMLTVGADYQDNDPKGSGWSGSFPLFDSQGNRNDVSRSFNNGAKWSSWEQYTRTVFANLEHNFANGWVGKVQLDHKINGYHAPLGAIMGDWPAPDNSAKIVAQKYTGETKSNSLDIYLTGPFQFLGREHELVVGTSASFSHWEGKSYWNLRNYDNTTDDFINWDGDIGKPDWGTPSQYIDDKTRQLGSYMTARFNVTDDLNLFLGGRVVDYRVTGLNPTIRESGRFIPYVGAVYDLNDTYSVYASYTDIFMPQDSWYRDSSNKLLEPDEGQNYEIGIKGEYLDGRLNTSLAYFEIHEENRAEEDALYNSKPTNPAITYAYKGIKAKTKGYEAEISGELAPGWQVQAGYTHKIIRDDSGKKVSTWEPQDQLSLYTSYKFKGALDKLTVGGGARWQGKSWQMVYNNPRSRWEKFSQEDYWLVDLMARYQITDKLSASVNVNNVFDKTYYTNIGFYTSASYGDPRNLMFSTRWDF
What is the function of this protein?
Receptor for the siderophore ferripyoverdine.
What are the official names of this protein?
Ferripyoverdine receptor.
What is the protein family that this protein belongs to?
Belongs to the TonB-dependent receptor family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: GP180_XENLA
Sequence: MLWSLFVVLQLVHTGRARTVHGSLDSDVAWHGRGQHIVTFLFHGDQAVLRVKINNVAAAAGKESALYLYQDEQWVQIHSSLEEYSCPERLSLAQDTIPLNQTEYNYTLPQMAYPKAWYVIYVDKFTCLVKYEDQKSDAITFEVAMLNPDAAGNPFDHFGADESGLHEFFFLLVLIYFVAACIYIQALWQMMKKGGPMHTVLKVLSTALLLQVVSALANYLHLSRYATDGKGAPLVGSLAELCDIASEVQMLYLLLSLCMGWTLSRKKKSQGKPLQWDRTPASTGIAVLAVSAQVILLVWELFEDANHHSFHAHQSLAENLLIAMKICLAISLACGLYQIITVERSTMKRQFYITFAKGCFLWFLCHPCFVAISFLFKEYQREKVITVGVIVSQSVSMIILYRLFLSHSLYWEVSSLSSVTLPLTVSSGHRSRYYS
What are the official names of this protein?
Integral membrane protein GPR180.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GPMA_LEPCP
Sequence: MYKLVLIRHGESTWNLENRFTGWTDVELTPTGVSQAQQAGRLLKEGGYEFDIAYTSVLKRAIWTLWHALDQMDRTWLPVAHSWRLNERHYGALQGLNKGDMAKQYGDAQVLIWRRSYDTPPPALEADDPRGQRQDVRYAKLDAEQVPLTECLKDTVARVLPFWNDSIAPAILSGKRVLIAAHGNSIRAMVKYLDGISDADIVNLNIPNGVPLVYELDADLKPIRSYYLGDAEAVAKAAAAVANQGKA
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: CCKAR_XENLA
Sequence: MESLRSLSNISALHELLCRYSNLSGTLTWNLSSTNGTHNLTTANWPPWNLNCTPILDRKKPSPSDLNLWVRIVMYSVIFLLSVFGNTLIIIVLVMNKRLRTITNSFLLSLALSDLMVAVLCMPFTLIPNLMENFIFGEVICRAAAYFMGLSVSVSTFNLVAISIERYSAICNPLKSRVWQTRSHAYRVIAATWVLSSIIMIPYLVYNKTVTFPMKDRRVGHQCRLVWPSKQVQQAWYVLLLTILFFIPGVVMIVAYGLISRELYRGIQFEMDLNKEAKAHKNGVSTPTTIPSGDEGDGCYIQVTKRRNTMEMSTLTPSVCTKMDRARINNSEAKLMAKKRVIRMLIVIVAMFFICWMPIFVANTWKAFDELSAFNTLTGAPISFIHLLSYTSACVNPLIYCFMNKRFRKAFLGTFSSCIKPCRNFRDTDEDIAATGASLSKFSYTTVSSLGPA
What is the function of this protein?
Receptor for cholecystokinin.  This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.  Has high affinity for CCK-8 and low affinities for gastrin-17-I, CCK-4, and unsulfated CCK-8.
What are the official names of this protein?
Cholecystokinin receptor, CCK-XLR.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HTF_CRYDW
Sequence: QLNFSPNW
What is the function of this protein?
Hypertrehalosaemic factors are neuropeptides that elevate the level of trehalose in the hemolymph (trehalose is the major carbohydrate in the hemolymph of insects).
What are the official names of this protein?
Hypertrehalosaemic factor, Adipokinetic hormone 1, CryDa-AKH-1, Hypertrehalosaemic neuropeptide.
What is the protein family that this protein belongs to?
Belongs to the AKH/HRTH/RPCH family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y2183_ALISL
Sequence: MDMTNAQRLILSNQYYLMSQMDPENAEKYQRQQLIVERGYELQIRELDKDFGSISETECREIIDFMEMYHAMQESYNMLIPECQAKVDARRLQFLGFDIATEAQQVNYVRFLTNSEGLYPQFDKADHHFNSQMPMMDKYRRMLTTWRNCPRQYHLCSTEMAQIFNA
What are the official names of this protein?
UPF0304 protein VSAL_I2183.
What is the protein family that this protein belongs to?
Belongs to the UPF0304 family.
Protein: DAPD_LARHH
Sequence: MTPIQALIEDAFERRADITPATVTPETKAAIDAVIADIDAGRLRVAEKIAGEWVTHQWLKKAVLLSFRIRDNAVLDDGVSRYFDKVDTKFADWDAARFQAAGFRAVPGAVVRKGSYIAKNTVLMPSFVNIGAFVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIEDNCFIGARSEIVEGVIVEEGSVISMGVYIGQSTRIFDRETGEVSYGRVPAGSVVVSGNLPSKDGSYSLYCAVIVKKVDAKTRGKVGINELLRGI
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS9_BARHE
Sequence: MAEINSLTELSVVTNTAETHENIAPVHVQKLDSQGRAYATGKRKDAVARVWIKPGSGKITINNKEFDKYFARPVLRMILRQPIVATNRDTQFDIIATVAGGGLSGQAGAVRHGISKALTYYEPELRTILKKGGFLTRDSRVVERKKYGKAKARRSFQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: RAD51_SCHPO
Sequence: MADTEVEMQVSAADTNNNENGQAQSNYEYDVNVQDEEDEAAAGPMPLQMLEGNGITASDIKKIHEAGYYTVESIAYTPKRQLLLIKGISEAKADKLLGEASKLVPMGFTTATEYHIRRSELITITTGSKQLDTLLQGGVETGSITELFGEFRTGKSQICHTLAVTCQLPIDMGGGEGKCLYIDTEGTFRPVRLLAVADRYGLNGEEVLDNVAYARAYNADHQLELLQQAANMMSESRFSLLVVDSCTALYRTDFSGRGELSARQMHLARFMRTLQRLADEFGIAVVITNQVVAQVDGISFNPDPKKPIGGNILAHSSTTRLSLRKGRGEQRICKIYDSPCLPESEAIFAINSDGVGDPKEIIAPV
What is the function of this protein?
Required both for recombination and for the repair of DNA damage caused by X-rays.  Binds to single and double-stranded DNA, in the presence of magnesium, and exhibits DNA-dependent ATPase activity.  Promotes DNA strand annealing and strand exchange via DNA recombinase activity and forms helical nucleoprotein filaments.
What are the official names of this protein?
DNA repair protein rhp51, RAD51 homolog.
What is the protein family that this protein belongs to?
Belongs to the RecA family. RAD51 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYF_LEMMI
Sequence: MQNRNTFFGVKQQITRFISVSIGIYVITQTSISNAYPIFAQQGYENPREATGRIVCANCHLASKPVDIEVPQSVLPDTVFEAVVRIPYDTQVKQVLANGKKGGLNVGAVLILPEGFELAPPDRISPELKEKIGNISFQSYSPTKKNILVIGPVPGQKYREIVFPILSPDPATSKDVHFLKYPIYVGGNRGRGQIYPDGSKSNNTVYNATSAGVVSKIVRKEKKGYEIIITDPSDGREVVDIIPPGPELLVSEGESIKLDQLLTSNPNVGGFGQGDAEIVLQDPSRVQGLLFFLASVVLAQIFLVLKKKQFEKVQLFEMNF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome f family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: QUEC_BORPE
Sequence: MFRCLMQNHQRRALVLFSGGQDSTTCLAWALERYAHVETLGFDYGQRHRVELDARQVVLRELRANFPDWAQRLGDDHLLDLGILAQVGDTAMTSDREIEMQANGLPNTFVPGRNLLFLTLAAALGYRRQLDVLVGGMCETDFSGYPDCRDDTIKSQQVTLGLGLGTRVTIETPLMWLDKAQTWELADRLGGQALVDMVIEHSHTCYLGERGQRHDWGYGCGHCPACALRKNGWERWVAGAAHAD
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: C5IT2_DERAN
Sequence: MRTLVASLCVFAVFSAVCCDVQERGHTYRTRNVTVEDGACVFERNVIPDGETKALNSPCVLSTCYAAAREVNSTLCPNIGVEQGCRVEWTPVGEYPNCCPKHVCPTTS
What is the function of this protein?
Complement inhibitor (PubMed:31871188).  Prevents complement-mediated activation of C5 by sterically preventing direct binding of C5 to its convertase (binding with domains MG4 and MG5) (PubMed:31871188) (By similarity).  Binds C5 at a different binding site than the other tick complement inbibitors OmCI and RaCI3, and the drug eculizumab (By similarity).  Inhibits the complement in human, rat and guinea pig, and also shows a reduced inhibition in rabbit and pig (By similarity).
What are the official names of this protein?
Complement inhibitor CirpT2.
What is the protein family that this protein belongs to?
Belongs to the CirpT family.
What are the subcellular locations of this protein?
Secreted.
Protein: INBD_SHIDY
Sequence: MIVCAEMDEQWGYVGAKSRQRWLFYAYDRLRKTVVAHVFGERTMATLGRLMSLLSPFDVVIWMTDGWPLYESRLKGKLHVIRKRYTQRIERHNLNLRQHLARLGRKSLSFSKSVELHDKVIGHYLNIKHYQ
What is the function of this protein?
Absolutely required for transposition of IS1.
What are the official names of this protein?
Insertion element iso-IS1d protein InsB.
What is the protein family that this protein belongs to?
Belongs to the transposase 27 family.
Protein: UBP3_MOUSE
Sequence: MECPHLSSSVCIAPDSAKFPNGSPSSWCCSVCRSNKSPWVCLTCSSVHCGRYVNGHAKKHYEDAQIPLLNHKRSEKQEKAQHTVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVREHLQNLENSAFTADRHRKRKLLENSSLNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQSLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDSNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSAILQENSTLSASNKCCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQENGPVCSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKALCLHLKRFHWTAYLRNKVDTYVQFPLRGLDMKCYLLEPENSGPDSCLYDLAAVVVHHGSGVGSGHYTAYAVHEGRWFHFNDSTVTVTDEETVGKAKAYILFYVERQARAGAEKL
What is the function of this protein?
Hydrolase that deubiquitinates monoubiquitinated target proteins such as histone H2A and H2B.  Required for proper progression through S phase and subsequent mitotic entry.  May regulate the DNA damage response (DDR) checkpoint through deubiquitination of H2A at DNA damage sites.  Associates with the chromatin (By similarity).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 3, Deubiquitinating enzyme 3, Ubiquitin thioesterase 3, Ubiquitin-specific-processing protease 3.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. USP3 subfamily.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes preferentially with monoubiquitinated H2A to chromatin.
Protein: CHIT_YEAST
Sequence: MSLLYIILLFTQFLLLPTDAFDRSANTNIAVYWGQNSAGTQESLATYCESSDADIFLLSFLNQFPTLGLNFANACSDTFSDGLLHCTQIAEDIETCQSLGKKVLLSLGGASGSYLFSDDSQAETFAQTLWDTFGEGTGASERPFDSAVVDGFDFDIENNNEVGYSALATKLRTLFAEGTKQYYLSAAPQCPYPDASVGDLLENADIDFAFIQFYNNYCSVSGQFNWDTWLTYAQTVSPNKNIKLFLGLPGSASAAGSGYISDTSLLESTIADIASSSSFGGIALWDASQAFSNELNGEPYVEILKNLLTSASQTATTTVATSKTSAASTSSASTSSASTSQKKTTQSTTSTQSKSKVTLSPTASSAIKTSITQTTKTLTSSTKTKSSLGTTTTESTLNSVAITSMKTTLSSQITSAALVTPQTTTTSIVSSAPIQTAITSTLSPATKSSSVVSLQTATTSTLSPTTTSTSSGSTSSGSTSSDSTARTLAKELNAQYAAGKLNGKSTCTEGEIACSADGKFAVCDHSAWVYMECASGTTCYAYDSGDSVYTQCNFSYLESNYF
What is the function of this protein?
Chitinase is required for cell separation during growth of S. cerevisiae.
What are the official names of this protein?
Endochitinase, Soluble cell wall protein 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.
What are the subcellular locations of this protein?
Secreted. Secreted, cell wall. Note=Most of the enzyme is secreted, but a significant amount of chitinase is also found associated with the cell wall through binding of C-terminal domain to chitin.