PharMolix/UniProtQA huggingface dataset:
Protein: MTNA_OSTLU
Sequence: MSSLEAIRYARGNLELLDQLALPLETKYIDVRDCNACWRCIKDMNVRGAPAIAIAAALALAVELEAKRGTLTTCEAAEAFVRERFDHMYTSRPTAVNLGEAKNRIQALAKRLSESGDVSGMIEGVIEGCEAMHAEDVASCRAIGDKGAAALLRACGAKDGENIKVMTCCNTGSLATAGYGTALGVIRALWESGRLERAYCLETRPYNQGSRLTAYELVYEKIPGTLICDNMAAALMARGDVDAIVVGADRVAANGDFANKIGTYSLAVNAKHHGVPMFTAAPVTTLDPETATGADIHIEERPGEEVTHSLGKRVAAEGIDVWNPSFDVTPAALLTGVITEHGVIEKNASGLFPVADFVAQAKGGT
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase, Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PYRB_PROMM
Sequence: MSGWSHRHILDLASFSLEDYSSVLELAHRFRSMPVTGARKLPALQGRLVATLFFEPSTRTRSSFELAARRLSADVQSFTPASSSLSKGETLLDTARTYVAMGADVLVVRHGSTSVPEQLACALDRSGERTAVLNGGDGLHSHPSQGLLDLYTLAHHFDPDHPLPEAIQGRRIVIVGDVLHSRVARSNLWALTACGADVVLCGPPSLVPQDFVAFVEAPPPGQAHDPVLHRGCVEVVRTLEEALPGADAVMTLRLQKERMHQHLLTDLNRFHRDYGLTHERLKLCGKPVPLLHPGPVNRGVELGGSLLDDHSISLVEEQVRNGIPIRMALLYLMAAFESSPDPSLEAIG
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: CCMA_XANC8
Sequence: MIDPLHTAPPLLAARALAFSRNEEPVFGPLDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVERGEILIDGKTARRGDRSRFMAYLGHLPGLKADLSTLENLHFLCGLHGRRAKQMPGSALAIVGLAGYEDALVRQLSAGQRKRLALARLWLSPAPLWLLDEPYANLDLEGITLVNRMISAHLRGGGAALVTTHGAYAAPPVRTRMLTLEAAA
What is the function of this protein?
Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NUOD_MYCTU
Sequence: MTAIADSAGGAGETVLVAGGQDWQQVVDAARSADPGERIVVNMGPQHPSTHGVLRLILEIEGETVVEARCGIGYLHTGIEKNLEYRYWTQGVTFVTRMDYLSPFFNETAYCLGVEKLLGITDEIPERVNVIRVLMMELNRISSHLVALATGGMELGAMTPMFVGFRAREIVLTLFEKITGLRMNSAYIRPGGVAQDLPPNAATEIAEALKQLRQPLREMGELLNENAIWKARTQGVGYLDLTGCMALGITGPILRSTGLPHDLRKSEPYCGYQHYEFDVITDDSCDAYGRYMIRVKEMWESMKIVEQCLDKLRPGPTMISDRKLAWPADLQVGPDGLGNSPKHIAKIMGSSMEALIHHFKLVTEGIRVPAGQVYVAVESPRGELGVHMVSDGGTRPYRVHYRDPSFTNLQSVAAMCEGGMVADLIAAVASIDPVMGGVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YB035_HUMAN
Sequence: MGLLSQRKWTLSGSQQTGCVALTVPSFPWVASRMHYGRKQVSWIIFLKIGAGCQVHVGHDCSTLRRQQGAPWSFASSFRPAASPLAPPSPGVSGLFPPHERWSGGSQTRCGKCVKMQILGSTLKLFRHPPSQVTRLWGRHHLKTPAPFLQSPGIQLNPGKVPASLLRLATWKPL
What are the official names of this protein?
Putative uncharacterized protein FLJ33534.
Protein: ADDB_BACC7
Sequence: MSLRFVIGRAGSGKSTLCLHEVQEELKQRPRGETILYLVPEQMTFQTQQALIGSEDVRGSIRAQVFSFSRLAWKVLQEVGGASRLHIDEAGVHMLLRKIVESRKDGLSVFQKAAEQNGFFEHLGSMIAEFKRYNVTPSNVYEMWQQLDAHSSSAEQKLLANKVYDLQLLYDDFERALIGKYLDSEDYLQLLVEKLPQSEYVKGAEIYIDGFHSFSPQELEIVRQLMICGARVTITLTIDEKTLAQPVNELDLFYETTLTYEKIKQVAREEKIEIEKTIPLMEQPRFHSPALAHLEAHYEARPNEKFNGEASVTIHTAANLRAEVEGVAREIRRLVADENYRYRDIAVLLRNGESYYDVMRTLFTDYNIPHFIDEKRPMSHHPLVECIRSALEIISGNWRYDAVFRCVKTELLYPLDVRKETMREEMDEFENYCLAYGVQGKRWTSEDPWMYRRYRSLDDTDGMITDSEREMEEKINRLRGVVRTPVIRMQKRLKRAGTVMQMCEAVYLFLEELDVPKKLEALRIRAEESGDFLFATDHEQVWEEVMSLLDTFVEMLGEEKMSLSMFTDVMSTGLEALQFANIPPSLDQVLIANIDRSRLSNVKATFVIGVNEGVIPAAPMDEGMLSDEERDVLSAAGIELAPTTRQTLLEEQFVMYQMVTRATEKLYISCPLADEEGKTLLASSFIKKIKRMFPDVKDTFITNDVNDLSRSEQISYVATPEVTLSYVMQQLQTWKRYGFEGNLDFWWDVYNFYVTSDEWKQKSSRVLSSLFYRNRAQKLSTAVSRDLYGDKIKGSVSRMELFNRCAYAHFAQHGLSLRERDIFKLDAPDIGELFHAALKRIADRLLRENRTWADLSIKECEHLSAVVIEEIAPLLQRQILLSSNRHFYLKQKLQQIIFRTSIILREHAKSSGFVPVDLEVPFGMGGTGSLPPMEFSLPNGVKMEVVGRIDRVDKAEDENGTFLRIIDYKSSSKALDLTEVYYGLALQMLTYLDVVTSNAHTWMKKGGTASPAGVLYFHIHNPIVEVKGDASEAEIEKEILKKFKMKGLVLGDADVVRLMDNKLSTGSSDIISAGLKKDGSFSARSSIASEQEFNVLQKYVHHTFENIGKDITEGVIDIAPYKKGNKAACTFCNFKSVCQFDESLEDNQFRTLKDMKDSEAMEKIREEVGGE
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease AddB, DNA 3'-5' helicase AddB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 1 subfamily.
Protein: FOLD_SULSY
Sequence: MILLDGKSLAEKIKNQIKQEIDQLTQKGYRQPVLSVILVGENPASQIYVNKKIKDCASVGIKSKPFFLPENITQTELLELIGDLNGDEEVDGILVQLPLPSHINTLEIIEAINPYKDVDGFHPINVGKLATGRNDAILPCTPYGIMKLLHEYNIDHFGKDVVVVGASNIVGKPMSLLFLKDEKSTVTICHKNTKDLKSHTLKADILVVAVGKPKLITEDMVKEGAVVIDVGINRVDGKIVGDVDFENVKKKAYAITPVPGGVGPMTVAMLLYNTLEIYKRKLIEI
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: G3P1_NOSS1
Sequence: MAKLKVGINGFGRIGRLVLRAGINNPNIEFVGINDLVPPDNLAYLLKYDSTHGRLRSQVETKDDGIVIDGHFIPCVSVRNPAELPWGKLGADYVVESTGLFTDSEGASKHLQAGARRVIISAPTKDPDRVRTLLVGVNHDLFDPSKDLIVSNASCTTNCLAPIAKVINDNFGLTEGLMTTVHAMTATQPTVDGPSKKDWRGGRGAAQNIIPSSTGAAKAVALVLPELKGKLTGMAFRVPTPDVSVVDLTFKTAKATSYKEICAAMKQASEGSLAGILGYTDEEVVSTDFQGDTHSSIFDAGAGIELNSNFFKVVAWYDNEWGYSNRVVDLMLSMVQKEQLAAV
What is the function of this protein?
Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD.  The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH.  The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase 1, GAPDH 1, NAD-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OX2V_HHV6U
Sequence: MSSLMLRLLPLLYIISAHFVLHPETSPSLIYEIGSIVTFHCRLETTTNIRSVSWYNKNRLISNHEVQNMDNLSFTDDGYVLIHELNKINNLAVDSKLYFHIKHNRTTSLLKIKAKSAYDATCLTCTFTVDNEKTSATSCLKLFMKPIVVLYFRYLDNFLDVTCTVTSYPKPNVVIKFLGEVYKRDIPIVRQNENGSSTVSVNFTFKRRTKLEFVGKTVSCLASSWFTNQKASALVTSGEHTVQNHDEYSKEGVKSSNSDETVFTWTVPLILILISVIVLLISVCIVAFKS
What are the official names of this protein?
Putative OX-2 membrane glycoprotein homolog, Protein U85.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MUTS_THEYD
Sequence: MEVSQEELTPLMRQYLRVKEQYKDAIVFFRLGDFYEMFGEDAVIASKILGITLTSRDKSKEKAIPMCGIPYFSADSYIEKLLREGYKVAICEQIGDPKTSKGIVEREVIKVLTPGTYLPEGVRENIYIMSIYPSKGKIGIALADITTGQFFLYETDKNITDEIERFEPKEILIPASFEDSLKFEISSYNKTFIEDWKFDYLLAYKTLLEHFKVASLKSYGAEEFSNAISAGGALLKYLEENKQQTEFKGIKILNLSEFMLLDASTKKNLEIFVSLDGSREGSLIWVLDETLTPMGARFLKNTLSCPLLNISEIEKRFDGIEAFCGDYLLREKLEKILKDFPDIERIALKIKGKSINPKELNSLKNALKRIPELREVLRNKTEILNSLYNSLYELNELVTKIENALTENPPPVITEGGIFRDGYNSTIDELRALRTESKKYILNMEAEERKKTGINSLKIGYNRVFGYYIEVTKPNLHLVPSHYIRKQTLANAERFITEELKELELKIMSAEEKLKILEQELFIELVNSILPFTDKILNNGETIGFIDFLLSLAKVASKYNYVRPEINEEDIIEIKDGRHPVIERLIQLGKLYEGRFIPNDLLIGPADQRIIILTGPNMAGKSTYMRQNALIVLMAQIGSFVPAKYAKIGIVDRIFTRIGASDYLAKGQSTFMVEMIETANILNNATPKSFIILDEVGRGTSTFDGISIAWSVVEYIAEKIKARTLFATHYHELTDLAFNLDCIKNFTVVVKEWGDEIIFLRKIQEGGADKSYGIQVARLAGLPLEILNRAREILHRLEKKEFQVFPIRARQLDLFFQGDPIKAELSKIDIDSLNPQKALKKLKELKEMLKND
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: Y3679_CUPPJ
Sequence: MNTIALYLLTAVAEILGCYLPYLWLRQGASAWVLLPGALSLALFAWLLSLHPDASGRVYAAYGGVYIGVAVLWLWLVDGVRPSAWDLAGVGVAFGGMAIIVFQPR
What are the official names of this protein?
UPF0060 membrane protein Reut_B3679.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PDXA_NEIMB
Sequence: MKQPVFAVTSGEPAGIGPDICLDLAFARLPCRCAVLGDKNLLRARAEALGKSVVLRDFDPESGGAAYGELEVLHIPAVEAVEAGKLNPANAAYVLQLLDTALAGISDGIFDGIVTAPLHKGIINDARASTGFFSGHTEYLAEKSGTGQVVMMLAGKGLRVALVTTHLPLKDVAAAITQPLIESVARILHHDLKHKFGIKNPKILVAGLNPHAGEGGHLGHEETDTIIPALENLRREGINLAGPYPADTLFQPFMLEGADAVLAMYHDQGLPVLKYHSFGQGVNITLGLPFIRTSVDHGTALDLAATGRADSGSLITAVETAVEMARGSL
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UL07_HCMVA
Sequence: MASDVSSHLLTVTQSRWTIHHMYNKLLILALFTPVILESIIYVSGPQGGNVTLVSNFTSNISARWFRWDGNDSHLICFYKRGEGLSTPYVGLSLSCAANQITIFNLTLNDSGRYGAEGFTRSGENETFLWYNLTVKPKPLETTTASNVTTIVTTTPTVIGTKSNVTGNASLAPQLRAVAGFLNQTPRENNTHLALVGVIVFIALIVVCIMGWWKLLCSKPKL
What is the function of this protein?
Plays a role in modulating the host immune response and affecting host cytokine production.  Structurally and functionally homolog of host CEACAM1, induces endothelial cell angiogenesis (PubMed:21670740).  Ligands for host FLT3 receptor, activates the PI3K/AKT and MAPK/ERK pathways.  In turn, triggers hematopoietic progenitor cell and monocyte differentiation leading to virus reactivation (PubMed:29691342).
What are the official names of this protein?
CEACAM1-like protein UL7.
What is the protein family that this protein belongs to?
Belongs to the RL11 family.
What are the subcellular locations of this protein?
Secreted. Host cell membrane; Single-pass membrane protein.
Protein: GLGC_RHORU
Sequence: MDQITEFQLDINRALKETLALVLAGGRGSRLRDLTNRESKPAVPFGGKYRIIDFPLSNCMNSGIRRMCVITQYRAHTLIHHIQRGWGFLRAEIGEFVELWPAQQQTDKESWYLGTADAVHQNLDLIRMHDPRFVLILAGDHIYKQDYSKLLAHHIARGSDCTVACVDVPREEATGYGCVEVDNDDNIVHFLEKPANPPGIPGRPDRAFASMGIYIFNADFLYEILESDALNEASQHDFGRDIIPSQVGKARIVAHRFSQSCVYSVGRREPYWRDVGTVDAYWSANIDLVSVTPALDLYDADWPIWTYQMQRPPAKFVFDTDERRGMAKDSLVSAGCIVSGGAVTGSLLFNDVRVNSYSSVIDTVILPMGDIGRHARLTKCILDTGCRIPEGLVIGEDPILDAKRFHVTEQGITLVTPDRLALL
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: PSBD_BUXMI
Sequence: MTIALGRFTKDENDLFDIMDDWLRRDRFVFVGWSGLLLFPCAYFALGGWFTGTTFVTSWYTHGLASSYLEGCNFLTAAVSTPANSLAHSLLLLWGPEAQGDFTRWCQLGGLWTFVALHGAFGLIGFMLRQFELARSVQLRPYNAIAFSAPIAVFVSVFLIYPLGQSGWFFAPSFGVAAIFRFILFFQGFHNWTLNPFHMMGVAGVLGAALLCAIHGATVENTLFEDGDGANTFRAFNPTQAEETYSMVTANRFWSQIFGVAFSNKRWLHFFMLFVPVTGLWMSALGVVGLALNLRAYDFVSQEIRAAEDPEFETFYTKNILLNEGIRAWMAAQDQPHENLIFPEEVLPRGNAL
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.  D2 is needed for assembly of a stable PSII complex.
What are the official names of this protein?
Photosystem II D2 protein, PSII D2 protein, Photosystem Q(A) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: FEN_SULTO
Sequence: MDLAELVEEIKKELSFAELKGKKISIDAYNALYQFLAAIRQPDGTPLMDSQGRVTSHLNGLFYRTISILEEGIIPIYVFDGKPPEQKAQELERRKKVKEEAEKKLEQAKTEGSIKTSELKKYAQMSIRLTNEMAEESKELLKAMGIPVVQAPSEGEAEAAYINILGLSWATASQDYDSLLFGAKRLIRNLTLSGKRKLPGKDVYVEIKPELIELDTLLKKLGLTREQLIDIGIIVGTDYNPDGIKGYGVKTAYRIIKKYGSLEKAIEKGEIPKIKVNFNVEEIRSLFLKPQVVEPKENLELVDCDSNKILDILVKTHDFNEERVKNGIERLEKAKREAKGASRQTGLDQWF
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity.  Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation.  Also involved in the base excision repair (BER) pathway.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA (By similarity).
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
Protein: TNPO1_ORYSI
Sequence: MAAAALWQPQEEGLREICTLLDAHISPNSDQARIWQQLQHYSQFPDFNNYLVFLLARGEGKSFEARQAAGLLLKNNLRATFSSMPPASQQYVKSELLPCIGATNKAIRSTVGTVISVLFQIVRVAGWIELFQALHQCLDSNDLDHMEGAMDAIYKICEDVPEELDVDVPGLPERPINVFMPRLLQFFQSTHAILRKLALGCINQYIVVMPAALYMSMDQYLQGLFNLAKDPSADVRKLVCSAWVQLIEVRPSILEPHLKNVTELMLQANKDSDDEVALEACEFWSAYCDVSMPPEGLREFLPRLIPTLLSNMSYSDDDESLADAEEEESFPDRDQDLKPRFHASRLHGSETGEDDDDDDAVNVWNLRKCSAAGLDVLSNVFGDDILPTLMPLIQQNLARTDDDAWKEREAAVLSIGAIAEGCITGLYPHLPQIVAFLIPLLDDKFPLIRSITCWTLSRYSKFIVQSLEHPNGREQFDKILLGLLRRVLDTNKRVQEAACSAFATLEEEAAEELVPHLGIILQHLMCAYGKYQRRNLRILYDALGTLADAVGAELNQAKYLDIFMPPLITKWQQLANSDKDLFPLLECFTSIAQALGPGFSQFAEPVFQRCINLIQSQHLAKVDPAAAGALYDKEFIVCALDLLSGLAEGLGAGIESLVSQSSLRDILLQCCMDEAADVRQSALALLGDLSRVCPIHLHPRLQEFLNVAAKQLNPQCVKEAVSVANNACWAIGELAIKIGKEISPVVITVVSCLVPILKSPEGLNKSLLENSAITLGRLCWVCPDIVAPHMDHFMQAWCNALCMIRDDFEKEDAFHGLCAMVAANPTGAVGSLTFICQACASWNEIKSEGLHNEVCQILNGYKQMLGSGGWEQCMSTLEPAVVQRLGRYGV
What is the function of this protein?
Functions in nuclear protein import as nuclear transport receptor.  Serves as receptor for nuclear localization signals (NLS) in cargo substrates.  Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism.  At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran.  The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity).
What are the official names of this protein?
Transportin-1, OsTRN1, Importin beta-2, Karyopherin beta-2.
What is the protein family that this protein belongs to?
Belongs to the importin beta family. Importin beta-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleoplasm. Note=Shuttles continuously between the nucleus and the cytoplasm.
Protein: HUTI_LEGPL
Sequence: MFACDELLLNASTIDATGLQLYNQAIVIRKGRIEWCGSEDQLPVHFQESAKSRKDCHGQLITPGLIDCHTHLVYAGHRAAEFRLKSQGVSYADIAKSGGGILSTVQMTRDASEEELIDQSLPRLLALKNEGVTTVEIKSGYGLDLQNELKMLRVARQLGDMAGVRVKTTFLGAHAVGPEFKGNSQAYVDFLCNEMLPAAKNMDLVDAVDVFCESIAFSIRQAEQIFQAAKNLNLPIKCHAEQLSNMGASSLAARYGALSCDHLEFLDENGALNMVKANTVAVLLPGAFYFLKEKQKPPVDLLRQVGVGMAIATDSNPGSSPTTSLLLMMSMACQFFSMSIPEVLSAVTYQASRALGMEKDIGSIEAGKIADLVLWSIKDSAALCYYFAYPLPHQTMVAGEWVS
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_CHLAA
Sequence: MPPLIESVVLQPLIAPIDPGADGRRSRRIERRSFARIKDAIDLPLLIETQLKSFEWFKREGLRELFDEISPITDFTGKNLELHFRDYTFGEPRYDEFECRERDLTYAAPLRVRVELRILTTGEIKESEIFLGDFPIMTDNGTFVYNGAERVVVSQLIRSPGVYFKDEKEPTSGRSLHTAKLIPNRGAWLEFETNKRDVISVKVDRKRKIPVTILLRAITAWIAEENGNGRWVPDNELDKFGHNDQIIELFRHVDTVPEHPYIHATLDKDPSRNAKEALLELYKRLRPGDPPTLENARSLIESLLFSPRRYDLAKVGRYKLNKNLWERDVRRDGAKAPDLSVRVLLPRDIFRIVEQLILLNNGHGRPDDIDHLGNRRVRTVGELIQQQFRVGLLRLERVVKERMSLQDPASATPNGLINIRPVVAAMREFFGGSQLSQFMDQTNPLAELTNKRRLSALGPGGLSRDRAGFEVRDVHHSHYGRICPVETPEGPNIGLIGTMSTFARVNEMGFLETPYRKVYNSVDNVQVWKEKGILLRDVRDLRTGDLIAAKGTRVNDEIARQITIGLLRGQILREDIVDPDTDELIAEAGTEINRALAERIVELPIKHIKIRPVVSQEVDYLSADEEDRFVIVQANAPLDQHNRFLDTIVSCRFGEDFVSERVERVDYMDVSPKQVVSVSTSLIPFLEHDDANRALMGSNMQRQAVPLLRPDAPIVGTGMEYRAARDSGQVIVARRDGVVVSTTSERIVIEEDDGNQTEYRLRKFMRSNQDTCINQRPAVVRGQRVKAGDVIADSSSTDQGELALGQNVLVAYMPWEGGNFEDAILVSERLVREDIFTSIHIEKYEVEARDTKLGPEEITRDIPNVGQESLRNLDERGIIYIGAEVQPNDILVGKITPKGETDLTAEERLLRAIFGEKAREVKDSSLRVPNGVRGKVIDVKVFSRSEGAELPVGVNQTVRVLLCQKRKISAGDKMAGRHGNKGVVSRVLPIEDMPFLPDGRPVDIILNPIGVPSRMNIGQILETHLGWAAARLGFRVATPVFDGAHEDQIKDLLVQAGLPADGKVTLYDGRTGERFDNPVTVGYAYMLKLAHLVEDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVVGRVKTYEAIVKGEPIQEAGVPESFKVLIKELQSLGLSVEVLSADEKPVELSDDLDSDIGALEGINLSGMERGEF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: FBL64_ARATH
Sequence: MDFVSRDRISSLPNPVVSHILSFLPTKEAASTSVLSKKWRYLFAYVTNLDFDDSDYQDGKPKSDVELSRSFMEFVDRVLALQGNGSVNKFSLECSNYDVDLARVTGWILNVLGRGVSELDLSILEYPLPSEIFVSKTLVRLKLGPANDLTLTLDRKDVFLPKLKTLYIDCVDVQERGFGFVKLLSGCPVLEELVLMNIGWENWKFCSVSVKTLKRLTFFCEETYENPKSVSFDTPNLVYLEYSDAIASKYPKVNFNSLVEAHIGLRLTEDQSGDADFSEEDYFSEGDEKKQMVGNATDFLKGISTVQILYLSAQAIEVLTFCCEPIPVFNNLIQLTIENNSEIRWDSLPGLLKNCPNLETLVLKRLLHKYNKACGNVCCCKRPKQPSCLSSSPVKVLKIFLFDDNDEEDGSEMRQIKYFLEKMPRLEELVVYYNTAYDPAVLELSKKLQKIPKIASPKCKIQVISENLSLSSTVPSFLTTRWSSLPPEEAYPWVDSPPPQIIDPMLEYGSPPEDDDSWLY
What are the official names of this protein?
F-box/LRR-repeat protein At3g59200.
Protein: RS21_COXBN
Sequence: MPMIDVPDNNAFDVAMRRFKRACEKAGILSKLRQIEYYEKPTSKRKRKRAAAVKRYAKKLQKEQEALERERTRY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: PDXH_SODGM
Sequence: MTEQLIDIAALRREYTRGGLRRADLTAEPMDLFEQWLKQACAAQLPDATAMSVGTVDENGQPYQRLVLLKHFDRQGMVFYTNLGSRKAAHLAHNPRISLHFPWHVLERQVLVLGRAERLSVIEVMKYFHSRPRDSQIGAWVSRQSSRISSRGVLESKFLELKQKFAQGDVPLPSFWGGYRVSIEAMEFWQGGEHRMHDRFLYRRENGGWHIDRLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: HEMA_I83A4
Sequence: MEKIVLLFAIVSLVRSDQICIGYHANNSTKQVDTIMEKNVTVTHAQDILEKTHNGKLCSLNGVKPLILRDCSVAGWLLGNPMCDEFLNVPEWSYIVEKDNPVNGLCYPGDFNDYEELKHLLSCTKHFEKIRIIPRDSWPNHEASLGVSSACPYNGRSSFFRNVVWLIKKNNAYPTIKRSYSNTNKEDLLILWGIHHPNDAAEQTKLYQNPTTYVSVGTSTLNQRSIPKIATRPELNGQSGRMEFFWTILKPSDTINFESNGNFIAPEYAYKIVKKGDSAIMKSGLEYGNCNTKCQTPIGAINSSMPLHNIHPLTIGECPKYVKSDRLVLATGLRNTPQRKRKKRGLFGAIAGFIEGGWQGMVDGWYGYHHSNEQGSGYAADKESTQRAIDGITNKVNSIIDKMNTQFEAVGKEFNNLERRIENLNKKMEDGFLDVWTYNAELLVLMENERTLDFHDANVKSLYDKVRLQLKDNARELGNGCFEFYHKCDNECMESIRNGTYNYPQYSEEARLNREEISGVKLESMGIYQILSIYSTVASSLALAIMIAGLSFWMCSNGSLQCRICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.