PharMolix/UniProtQA huggingface dataset:
Protein: SYL_YERPP
Sequence: MQEQYRPEDIETQVQLHWQEKQTFKVTEDASKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVISRYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIEYMKNQLKLLGFGYDWDREIATCKPDYYRWEQWFFTKLYEKGMVYKKTSAVNWCPHDLTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITDYAEQLLNDLDTLESWPEQVKTMQRNWIGRSEGVDIVFDVVDSEEKLSVYTTRPDTFMGVTYVAVAAGHPLSLQAAATNPALADFVAECRNTKVAEAEMATMEKKGMATGLYAIHPLTGEKLPIWAANFVLMDYGTGAVMAVPGHDARDWEFATKYNLPIKPVILAADGSEPDLSQEAMTEKGTLFNSGEFDGLNHEDGFNAIADKLVALGVGQRKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVVPTPEDQLPVILPEDVVMDGISSPIKADPEWAKTTVNGIPGLRETDTFDTFMESSWYYARYTCPQYDDGMLDPAAANYWLPVDQYVGGIEHAIMHLMYFRFFHKLLRDAGLVDSDEPAKRLLCQGMVLADAFYYTGNNGERIWVSPVDAIVERDDKGRIVKAVDAEGHELVYAGMSKMSKSKNNGIDPQVMVEKYGADTVRLFMMFASPAEMTLEWQESGVEGANRFLKRVWRLAFDHTAKGAVKPLDIASLTEEQKSLRRDLHKTIAKVTDDVGRRQTFNTAIAAVMELMNKLGRAPQETEQDRALMQEALLAVVRMLYPFTPHVCFSLWQALGGEGDIDTAPWPIADEQAMVEDSKLVVVQVNGKVRGRITVPADATEQQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_BLAVI
Sequence: MSGHSSYQPSTGIERWLDTRLPIVRMMYDQFVAFPVPKNINYAYAFGAILAVFLIIQIVSGVVLAMHYVAQDTLAFASIEHIMRDVNYGWLIRYIHMNGASFFFFAVYAHTFRGMYYGSYKEPREVLWILGVIIIILMMATAFMGYVLPWGQMSFWGATVITNLFSAIPYIGDPIVTWLWGGYSVGNPTLTRFYSLHYLLPFVIVGVVMLHVWALHVTGQTNPTGVEVKSEKDTVRFTPFALTKDAVALGVCFIAFAWFVFFVPNYLGHADNYIPANPGVTPAHIVPEWYLLPFYAILRAVPDKLGGVIAMFGALVVLLFLPWLDGSKVRSAAYRPLYRIFFWLFVADCIFLGWLGAMPAEGIYPTLSQVGTVWYFAHFLVIVPALGYFEKPKPLPESISAAVLEAHSRPSLLARLINR
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
What are the official names of this protein?
Cytochrome b.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ASPGA_ARATH
Sequence: MVGWAIALHGGAGDIPIDLPDERRIPRESALRHCLDLGISALKSGKPPLDVAELVVRELENHPDFNAGKGSVLTAQGTVEMEASIMDGKTKRCGAVSGLTTVVNPISLARLVMEKTPHIYLAFDAAEAFARAHGVETVDSSHFITPENIARLKQAKEFNRVQLDYTVPSPKVPDNCGDSQIGTVGCVAVDSAGNLASATSTGGYVNKMVGRIGDTPVIGAGTYANHLCAISATGKGEDIIRGTVARDVAALMEYKGLSLTEAAAYVVDQSVPRGSCGLVAVSANGEVTMPFNTTGMFRACASEDGYSEIAIWPNN
What is the function of this protein?
Acts in asparagine catabolism but also in the final steps of protein and degradation via hydrolysis of a range of isoaspartyl dipeptides.  The affinity for Asn and at least 4 isoaspartyl dipeptides (L-beta-Asp-Ala, L-beta-Asp-Gly, L-beta-Asp-Leu, L-beta-Asp-Phe) is quite low, KM being greater than 4. 0 mM.  The enzyme is inactive on alpha-aspartyl dipeptides.
What are the official names of this protein?
Isoaspartyl peptidase/L-asparaginase 1, L-asparagine amidohydrolase 1.
What is the protein family that this protein belongs to?
Belongs to the Ntn-hydrolase family.
Protein: RB11B_DIPOM
Sequence: MGTRDDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADNNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNNLSFIETSALDSTNVEEAFKNILTEIYRIVSQKQISDRSAHDESPGNNVVDISVPPTTDGQKSNKLQCCQNM
What is the function of this protein?
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes.  Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion.  That Rab plays a role in endocytic recycling, regulating apical recycling of several transmembrane proteins including cystic fibrosis transmembrane conductance regulator/CFTR, epithelial sodium channel/ENaC, potassium voltage-gated channel, and voltage-dependent L-type calcium channel.  May also regulate constitutive and regulated secretion, like insulin granule exocytosis.  Required for melanosome transport and release from melanocytes.  Also regulates V-ATPase intracellular transport in response to extracellular acidosis (By similarity).
What are the official names of this protein?
Ras-related protein Rab-11B, ORA3.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Recycling endosome membrane; Lipid- anchor; Cytoplasmic side. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side.
Protein: SFSA_SYNJA
Sequence: MPAQEGPPPYCFSTPLRRGVLRSRYRRFFAEVELENGQPVTAHCPNTGPMTGVCQVGAPVYLSYHPDPKRKLAYTWEMIQVEGVWVGINTGLPNRLVEWGLARGWFPQLAEFSRWQREVTCGRSKIDFLLMGDSGLAYLEVKNTTWAVGSRALFPDTVTTRGQKHLEDLIEIRRQGQRALLLYWINRADCTEFAPGEERDPRYAHLFRQALQAGVEVLPYRIAVSPQGIRPLGLAKIVA
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: VPS36_DANRE
Sequence: MDRFMWTNGLLEMNETLVIQQRGVRLYDGEDKAKLDVGGVVLSTHRLLWRDQKNHECCICIPLSQVIFFEEQAAGIGKSAKIVIHLHPAPENKEPGPYQHSKYSYIKLSFKEHGQIEFYRRLTEEMTQKRWENTPVSQPIPTGTGPKAGRTRAVGIVGIERKLEEKRKETDKNISEAFEDLSKLMEKAKEMVELSRSIANKIKDKQGDITEDETIRFKSYLLSMGIANPVTRETHGSGTQYHIQLAKQLGDMLQAPLEERGGMMALTEVYCLVNRARGMELLSPEDLVNACKIFESLKLPLRLRVFDSGVMVVQLQSHSEEEMIASALDNVSDKGSLTAEEFAKLLGLSVLLAKERLLLAEKMGHLCRDDSVEGLRFYPNLF
What is the function of this protein?
Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.  The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation.  The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex.
What are the official names of this protein?
Vacuolar protein-sorting-associated protein 36, ESCRT-II complex subunit VPS36.
What is the protein family that this protein belongs to?
Belongs to the VPS36 family.
What are the subcellular locations of this protein?
Cytoplasm. Endosome.
Protein: ARNT_SHESH
Sequence: MDKSKINLAVIVPLFFIMLYLLPLGLRDLWSPDELRYAEIAREMVDSGNWIVPTFNDIRYFEKPVMGHWMNAISQVLFGENNFSVRAASAFSTLGAAFCLFLLVGRFANRKQAWVTVSVFLSLFLVSNLGTYSVLDGMLNLWLTAAFTAFFYAADSPTTSQRCRFYGLAGLFCACALLTKGFLALALPVIVVVPFMIWQRQLVDILRWGWWVMLVALIVTLPWALAIHAAEPDYWHYFFWVEHIQRFAAEDAQHTSPAWYYLPYLLLGTLPWLFLAPSAIKHLKGHWQSPLLRYALLWALIPFIFFSAAKGKLVTYILPCMAPLAIILAQGIISAFENRAKGLKIGSVINCAFFSLISVAVIVLFYMGRLPLEAEEFYRPWLLVVVCGSWAVLAYISIKAKSLEGKIASYMLMPLSLFLLAWAIIPNISIDSKMPGRFLEQVSPLVSDDAILIADYPSTMSAFNWYFKRRDVYLTGNTGEVSYGIGYDDAKHKYVAPSLLGEFIRKQSVPVVILFREMDVPQSLPEPDKRIERGKFTLVYYDRVKR
What is the function of this protein?
Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase, 4-amino-4-deoxy-L-arabinose lipid A transferase, Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase, Undecaprenyl phosphate-alpha-L-Ara4N transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 83 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BIOB_PSEA8
Sequence: MSATASVATRHDWSLAEVRALFEQPFNDLLFQAQTVHRAHFDPNRVQVSTLLSIKTGACPEDCKYCPQSGHYNTGLDKEKLMEVQKVLEAAAEAKAIGSTRFCMGAAWKHPSAKDMPYVLEMVKGVKKLGLETCMTLGRLTQEQTQALADAGLDYYNHNLDTSPEFYGNIITTRTYSERLQTLAYVREAGMKICSGGILGMGESVDDRAGLLIQLANLPEHPESVPINMLVKVKGTPLAEEKDVDPFDFIRTLAVARIMMPKSHVRLSAGREQMNEQMQALAFMAGANSIFYGEKLLTTKNPQAEKDMQLFARLGIKPEEREEHADEVHQAAIEQALVEQRESKLFYNAASA
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: PKNI_MYCTU
Sequence: MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRETEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTAVAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQPSYPAPELSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGPLQPPKLSAFRPDLARLDGVLSRALATAPADRFGSCREFADAMNEQAGVAIADQSSGGVDASEVTAAAGEEAYVVDYPAYGWPEAVDCKEPSARAPAPAAPTPQRRGSMLQSAAGVLARRLDNFSTATKAPASPTRRRPRRILVGAVAVLLLAGLFAVGIVIGRKTNTTATEVARPPTSGSAVPSAPTTTVAVTAPVPLDGTYRIEIQRSKQTYDYTPTPQPPDVNTWWAFRTSCTPTECLAAATMLDDNDHTQAKTPPVRPFLMQFGEGQWKSRPETVQFPCVGPNGSPSTQATTQLLALRPQPQGDLVGEMVVTVHSNECGQQGAVIRIPAVASRSGDLPPAVTVPDPATIPDTPDTTSTATLTPPTTTAPGPGR
What is the function of this protein?
Plays an important role in slowing down the growth of mycobacteria within the infected host.
What are the official names of this protein?
Serine/threonine-protein kinase PknI.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Single-pass membrane protein. Note=More abundant in the cytosol than in the cell membrane.
Protein: AZOR_PELUB
Sequence: MKIYQIDSSARKEGSSSRALAKKLLNKIKKPGDEVIYRDLDDDMLFVSGLTESGMKIAEKDQTEEHKKMFELSDKLVSELKESDIIIISAPIYNYGPPATLKAWCDLAARIGETFKFKPNGRREGLLKNKQAYLVITSGGTKLNSSEDFLTPWLKFILNFFGIEKVEVISADQMALDYEKSIKEAEKQIENII
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: PYRD_METFK
Sequence: MLYSIVKPWLFRLDAERAHDFTLKNLKRLERSGLLNLYPRPPKCKQRQVMGINFPNPVGLAAGLDKNGAYIDALAGLGFGFIEIGTITPRPQPGNPKPRMFRLPEAQGVINRFGFNNLGVDVLLRNVAATKYKGVLGINIGKNFDTPNERAVDDYLHCLRKVYPYAHYVTVNISSPNTKNLRALQEKEALGQLLHALKQEQQVLADQHGRYVPIALKIAPDLDEGQVADIAALLMKHQFDGVIATNTTLARDMVQALPCAQEAGGLSGAPLRDRSTAVIQSLSNHLAGALPIIGVGGILSGEDAEQKIKAGASLVQVYSGLVYRGPVLVDDICRTLG
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PTER_DROPE
Sequence: MTAVETVLGSITPNLLGRTLTHEHVALDFEHFYRPPPADFESELKAKISMSTLGYVRLYPYSSKENVRFYDEEALEAAKKDVLLYKKHGGGSIVENSSYGLKRNLEFIVELAKSTGVHFIAGTGHYIHAVQDASHASLTVEQMSDLYTKDILTGIEIKGKMVKCGFIGEVASVYPIHEFEKNSIKATGEIQEVLGCGVSFHPHRDAQAPFDIMRLYLEAGGRAQKCVMSHLDRTLFKIEQLVELSELGCYLQYDLFGTECSYYQLNTNVDMISDGQRIENLMKLIEEGLLDRLLMSHDIHTKHRLTSYGGHGYHHIHTNILPRMFARGVTLEQVEQMTVTNPANWLSFDP
What are the official names of this protein?
Phosphotriesterase-related protein, Parathion hydrolase-related protein.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
Protein: PSUG_HERA2
Sequence: MTKLILAPEVQAAFANGQPVVALESTVISHGLPYPHNREIALQLEATVRAGGAVPATIAVIQGQVHVGLTNEQIEHFATATDVLKLSRRDIGYAVAAGRDGATTVAATMAIAELAGIQVFATGGIGGVHRGARDTWDVSADLGELGKSSVLVVCAGAKSILDLPATLEVLETYGVPVVGYTTEELPAFYSAHSGLQLGRRVDDPTQAAAAWAAHRLYGGGSGMVLAVPPPVEKALDPQFVEAAIGRAIAQAEAAGIRGAAVTPFLLSAMARETEGESIATNTALLNNNAQVAAQVAVALFQSV
What is the function of this protein?
Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil.  Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
What are the official names of this protein?
Pseudouridine-5'-phosphate glycosidase, PsiMP glycosidase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine-5'-phosphate glycosidase family.
Protein: MUKB_VIBVU
Sequence: MIERGKYQSLTMVNWNGFFARTFDIDGLVTTLSGGNGAGKSTTMAAFITALIPDQSLLHFRNTTEAGSSQASRDKGLYGKLQPGACYAALDVVNSRNQRLLFAVKLQQVAGRDKKVDIKPFVIQGLPSHVKPTDVLIESVSATQARVRQINEVKESVAQYEGVQFKSFSSIVDYHAQMFEFGVIPKKLRNSSDRSKFYRLIEASLYGGISSAITRSLRDYLLPQNGGVKKAFQDMESALRENRMTLEAIKTTQADRDLFKHLITESTNYVAADYMRHANERHKKLEQSLSLRSELFSSRETLIEQNRLLNQVQQELEMLVESESALEQDYQGASDHLQLVQNALRQQEKIERYQEDLEELNERLEEQSMVVEEAQERVLMAEEQSTVAENEVDSLKTQLADYQQALDVQQTRALQYQQAVQALEKAKVLLSDSTLTAESAQALVAQLTQSEAEQTQALLALKHKLDMSSAAAQQFENALKLVHSIAGQVERAEASRHAKAAIQQARSAQQVVQNENQWRAQHRDLERSLNQQNQAQALVAEYQKAHQVTLDDEVMFEQERERHHAQLDSLEIALEENRELRSEQRRQEQDLQSDITQLQAIAPKWIAANDALEKLREQSGAELADSQSVMSQMQQVLEQEKQLSQAKDKLAERRSQLESEIERLASPGGSNDPRLKGLADTLGGVLLSEIYDDITIDDAPYFSAMYGPARHAIVVSDLSGIEEKLVELDDCPEDLYIIEGDVDAFDDSSIKAEELEGAVCVRLNDRQMRYSRFPVIPLFGRAAREQRLELLRSEREEVVEKHAKAAFDAQKMQRLFQAFNQFVAEHIQVAFAADPEQALVIARDKRNQLTRTLAELEAKELQMRSQIQNSKQALTMLDKLAPMMAVISDDTIGERFAELEEKIAQLADAKQFLGAHAKAVEQLESQLAVLDADPEQFDALEAQYQSADSQLQALKKQIFALSDLVERRHYFAYADSVDLLSKSSELSEQLKAKLVEAERARSRYRDELKQQQEQMNQYNQVLASLKSSYQAKLETVQEFKQELAEFGVSADEGALERAIRRRDELHERLHTSRSRKSEYERTLTSTELGMKELAKRLKKVQKEYVELRTFVVAAKAGWCSVLRLARENDVERRLHKRELAYLSAGELRSMSDKSLGALRLAVANNDDLRDALRLSEDNARPERKVLFYIAVYQHLRERIRQDIIHTDDPVEAIEEMEVELARLTEELTMRENRLAISSESVASIIKKTIQREQNRIRMLNQGLSNISFGQVKGVRLNVKVRESHEVLLNGLATQQEQHKDLFETARYTFSEAMAKLFQRVNPHIDMGQRSPQVLGEELLDYRNYLELSIEVNRGSDGWLQAESGALSTGEAIGTGQSILLMVVQSWEEESRRLRSKDIVPCRLLFLDEAARLDAKSISTLFELCDRLDMQLLIAAPENISPEKGTTYKLVRKVFKDHEHVHVVGLRGFGQEQKPKSEAQQMIEEFEA
What is the function of this protein?
Plays a central role in chromosome condensation, segregation and cell cycle progression.  Functions as a homodimer, which is essential for chromosome partition.  Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes.  May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
What are the official names of this protein?
Chromosome partition protein MukB, Structural maintenance of chromosome-related protein.
What is the protein family that this protein belongs to?
Belongs to the SMC family. MukB subfamily.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: NHAP2_YERP3
Sequence: MDAITINSLFLVGAVLVAASILLSSFSSRLGIPILVIFLAIGMLAGTDGLGGIAFDNYPAAYLVSNLALAVILLDGGMRTRASSFRVALWPALSLATFGVIITAGLTGLVAAWLFNLDIIQGLLIGAIIGSTDAAAVFSLLGGKGLNERVSATLEIESGSNDPMAVFLTVTLIAMIAAGETSLSWMFLVHLIQQFGLGIIIGLLGGGLLLLLINRMELANGLYPLLAVSGGILVFALATALNGSGILAVYLCGLLLGNRPIRNRAGILQTFDGLAWLSQIGMFLVLGLLLNPSDLLPIAIPALLLSLWMILFARPLSVFIGLLPFRSFNLRERVFISWVGLRGAVPVILAVFPMMAGLPNANLFFNVAFFVVLVSLLLQGTTLSFAARKAKLVVPPTLAPVSRIGLDIDMNNQWEQFIYQLSCDKWCIGATLRDLKMPQGTRIAALFRGKDLLHPTGSTRLKEGDILCVIGQEHDLPALGKLFSQSPNIQLDERFFGDFILDADAKLQDISQIYGLNLEPTVDKQQTLGQFVLYLFGGEPVIGDQIEWDGLTWTIAEMESDRVSRVGVKIVTDKA
What is the function of this protein?
K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.
What are the official names of this protein?
K(+)/H(+) antiporter NhaP2, Potassium/proton antiporter NhaP2.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYAS_METB6
Sequence: MIPKYRIRCISGGEIVPDITSLSCPAGHDSLLRTEYTSRRLQLSYHSGIFRYLCWLPVTAPLLPSGGPVTFTSDELSRELGLSRLAISFSGYSPEHHASLTTGSFKELEALATLQRLWELGKKIPVIASAGNTGRAFAGLSAQYGKPVVVVVPSSAVSRLWTTTPAQDVFLVAVDGDYTDAIAVSTALATVPGCVPEGGARNVARRDGMGTTVLDAAVTLGRIPDHYFQAVGSGTGAIAAWEAALRLIGDGRYGTKLPRLHLAQNKPFTPIVLAWQQRRRTFKPELDMPDAPNAIKEVMSPVLTNRSPPYGIGGGLFDALQATEGQMYAVSNDEGKKGMALIRDTLGIDPDPAAAVATAALVQAAAAGTVGPDDSILLNITGGGYERIREDYTLYPIEPSVTVNQHETGDTLKAELSRWVAHYG
What is the function of this protein?
Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate.
What are the official names of this protein?
Cysteate synthase, CS, Cya synthase.
What is the protein family that this protein belongs to?
Belongs to the threonine synthase family. Cysteate synthase subfamily.
Protein: PLSX_BORPA
Sequence: MIRIAIDCMGGDFGLPVTIPAAIEFARQFPDTRLLLVGLPDAIEAALAERRDAPRDRLDIVPATEVVSMDDPVEVALRRKKDSSMRLAAQAVKDGRADACISAGNTGAWMAISRYVLKTLDGIDRPAIATSIPNQTGRATTVLDLGANVDCSAEHLLQFAIMGAALSQAVDHRDRPTVGLLNIGEEIIKGNEVVKEAAELLRASPLNFYGNVEGNDIFKGTVDVVVCDGFVGNVVLKSVEGLAKMLSSVIREEFKRNFITLLAGAFAKPVLNRLRNRVDNRRYNGAALLGLRGVVIKSHGSADAYAFGFALQRAREAVASKLLERTAQTVAQITQRVQSGEAVAPGAAGDTA
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: KPCI_DANRE
Sequence: MPTLRDSTMSHPGENPHQVRVKAYYRGDIMITHFEPSISYEGLCNEVRDMCSMDNDQLFTMKWIDEEGDPCTVSSQLELEEALRLYELNKDSELIIHVFPCVPEKPGMPCPGEDKSIYRRGARRWRKLYYATGHAFQAKRFNRRAHCAICTDRIWGLGRQGYKCINCKLLVHKKCHKLVTVECGRQVIQDPMIGRIDPGSTHPEHPDQVLGKKNSTESINHEGEEHEAVGSRESGKAVSSLGLIDFDLLRVIGRGSYAKVLLVRLKKTERIYAMKVVKKELVNDDEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRSLSVKAASVLKGFLNKESKERLGCHPQTGFADIMAHPFFRNVDWDLMEQKQVVPPFKPNISGEFGLDNFDAQFTNEPIQLTPDDDDAVKKIDQSEFEGFEYINPLLMSAEECV
What is the function of this protein?
Calcium- and diacylglycerol-independent serine/ threonine-protein kinase that plays a general protective role against apoptotic stimuli, is involved in NF-kappa-B activation, cell survival, differentiation and polarity, and contributes to the regulation of microtubule dynamics in the early secretory pathway (By similarity).  Is required for the formation and maintenance of the zonula adherens during early epithelial development and plays a critical role in organ morphogenesis and in regulating the orientation of cell division.
What are the official names of this protein?
Protein kinase C iota type, Atypical protein kinase C-lambda/iota, aPKC-lambda/iota, Heart and soul protein, nPKC-iota.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
Protein: SYM8_PEA
Sequence: MAKSNEEPNSNLNTNKPPLKRTKTLAQQPSLNLRVSIAAADNGIGNSSSSSTKTDFEQQQRNYPSFLGIGSTSRKRRPPPPPKPSNITPNVKPPASDFQTKPHSEPKTSPSSSSPPSLPIAITKQQQQQHSISSPIFYLFVITCVIFVPYSAFLQYKLAKLKDMKLQLCCQIDFCSGNGKTSLQKDVVDDGSFSYYILNADSRTISLYIVLFTLVLPFILYKYIDYLPQMINFSRRTNSNKEDVPLKKRVAYMVDVFFSIYPYAKLLALLFATLFLIAFGGLALYAVTGGSMAEALWHSWTYVADAGNHAETEGMGQRIVSVSISAGGMLIFAMMLGLVSDAISEKVDSLRKGKSEVIERNHVLILGWSDKLGSLLKQLAIANKSVGGGVIVVLAEKEKEEMEMDIAKLEFDFMGTSVICRSGSPLILADLKKVSVSKARAIIVLASDENADQSDARALRVVLSLTGVKEALRGHVVVEMSDLDNEPLVKLVGGELIETVVAHDVIGRLMIQCALQPGLAQIWEDILGFENAEFYIKRWPELDGLLFKDILISFPDAIPCGVKVSADGGKIVINPDDNYVLRDGDEVLVIAEDDDTYAPGPLPEVRKGYFPRIRDPPKYPEKILFCGWRRDIDDMIMVLEAFLAPGSELWMFNEVPEKQRERKLAAGELDVFGLENIKLVHREGNAVIRRHLESLPLETFDSILILADESVEDSVAHSDSRSLATLLLIRDIQSRRLPYRDTKSTSLRLSGFSHNSWIREMQQASDKSIIISEILDSRTRNLVSVSRISDYVLSNELVSMALAMVAEDKQINRVLEELFAEEGNEMCIKPAEFYLFDQEELCFYDIMIRGRTRKEIVIGYRLASQERALINPSEKSMTRKWSLDDVFVVIASGE
What is the function of this protein?
Required for both rhizobial and mycorrhizal symbiosis.  Involved in Nod-factor-induced calcium spiking.  May induce a change in membrane polarization that activates the opening of a calcium channel required for calcium spiking.  Might be calcium gated.
What are the official names of this protein?
Probable ion channel SYM8, DMI1 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the castor/pollux (TC 1.A.1.23) family.
What are the subcellular locations of this protein?
Nucleus membrane; Multi-pass membrane protein.
Protein: Y2620_STAA3
Sequence: MTNFTFDGAHSSLEFQIKHLMVSKVKGSFDQFDVAVEGDINDFSTLKATATIIPSSINTKNEARDNHLKSGDFFGTDEFDKITFVTKSVSESKVVGDLTIKGITNEETFDVEFNGVSKNPMDGSQVTGIIVTGTINREKYGINFNQALETGGVMLGKDVKFEASAEFSISE
What are the official names of this protein?
UPF0312 protein SAUSA300_2620.
What is the protein family that this protein belongs to?
Belongs to the UPF0312 family.
Protein: RL5_IDILO
Sequence: MAKLHDFYRESVVPELMKEFSYNSVMQVPRIDKITLNMGVGEALADKKVLDNAVADLEAISGQKPIRTVARKSVAGFKVREGFPIGCKVTLRGERMWDFLQRLISIAIPRIRDFRGLNPKSFDGRGNYSMGVREQIIFPEVDYDKVDKVRGLDITITTNAGTDDEARALLAAFNFPFRK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: FOLD_RHOP5
Sequence: MSARIIDGKVISAELRARVAAEVTRIKTDHGITPGLAVVLVGADPASEVYVRSKHKQTQEAGMASFEHRLPADVPQAELLALIAKLNADPTVHGILVQLPLPKGLDSNAVIDAIDPAKDVDGLNPVNAGRLASGLFALTPCTPLGCIIMAKQVHASLEGMNAIVVGRSNLVGKPLVQLLLNENATVTIAHSRSRDLPALCRQADLVFAAVGKPEMIRGDWIKPGATVIDVGINRTPSPDGGKDKLVGDVAFAEAKEVAGAITPVPGGVGLMTVACLLVNTVRAASAIHGLPKPAV
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: TX19A_MOUSE
Sequence: MCPPVSVRHGARGMSCLYEAWLYHLVHGEQTKICFACFKAAFLLNKLYLEMGDWQEEEEEEEEEDADLLEYLSESESESEQEPGPEQDAWRGLGSLYVPQSVSEGSGVLLPTPVWTQGILFSIFVPTELFPQEAVPLDLGPEDAEWTQALPWRLDGLFPCSHQLIPPLTWWDIFDVMPSPGQPVLLELRCHWPLDQTVAQSWLQDQKFVLLLDSVQSRCHLLSMRVRWVVRTQVQHWQVLLDPGEMWVAHFRKEVGQHGLYHQSLNPWRLSILTASELGMELLPATCYLWNKGFWVGSFLPWHINMPETWSWEPGERLFITDATICGTDYHLAQSFLDSHPTPHPLLTLTP
What is the function of this protein?
Required during spermatogenesis and placenta development, participating in the repression of retrotransposable elements and preventing their mobilization (PubMed:18802469, PubMed:21103378, PubMed:23364048, PubMed:23674551, PubMed:28254886).  With its paralog, Tex19. 2, collaborates with the Piwi-interacting RNA (piRNA) pathway, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins.  Interacts with Piwi proteins and directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements (PubMed:28254886).  Also during spermatogenesis, promotes, with UBR2, SPO11-dependent meiotic recombination (PubMed:28708824).  Interacts with LINE-1 retrotransposon encoded LIRE1, stimulates LIRE1 polyubiquitination, mediated by UBR2, and degradation, inhibiting LINE-1 retrotransposon mobilization (PubMed:28806172).
What are the official names of this protein?
Testis-expressed protein 19.1, mTex19.1, Testis-expressed protein 19A.