PharMolix/UniProtQA huggingface dataset:
Protein: COLH_HATHI
Sequence: MKRKCLSKRLMLAITMATIFTVNSTLPIYAAVDKNNATAAVQNESKRYTVSYLKTLNYYDLVDLLVKTEIENLPDLFQYSSDAKEFYGNKTRMSFIMDEIGRRAPQYTEIDHKGIPTLVEVVRAGFYLGFHNKELNEINKRSFKERVIPSILAIQKNPNFKLGTEVQDKIVSATGLLAGNETAPPEVVNNFTPILQDCIKNIDRYALDDLKSKALFNVLAAPTYDITEYLRATKEKPENTPWYGKIDGFINELKKLALYGKINDNNSWIIDNGIYHIAPLGKLHSNNKIGIETLTEVMKVYPYLSMQHLQSADQIKRHYDSKDAEGNKIPLDKFKKEGKEKYCPKTYTFDDGKVIIKAGARVEEEKVKRLYWASKEVNSQFFRVYGIDKPLEEGNPDDILTMVIYNSPEEYKLNSVLYGYDTNNGGMYIEPEGTFFTYEREAQESTYTLEELFRHEYTHYLQGRYAVPGQWGRTKLYDNDRLTWYEEGGAELFAGSTRTSGILPRKSIVSNIHNTTRNNRYKLSDTVHSKYGASFEFYNYACMFMDYMYNKDMGILNKLNDLAKNNDVDGYDNYIRDLSSNYALNDKYQDHMQERIDNYENLTVPFVADDYLVRHAYKNPNEIYSEISEVAKLKDAKSEVKKSQYFSTFTLRGSYTGGASKGKLEDQKAMNKFIDDSLKKLDTYSWSGYKTLTAYFTNYKVDSSNRVTYDVVFHGYLPNEGDSKNSLPYGKINGTYKGTEKEKIKFSSEGSFDPDGKIVSYEWDFGDGNKSNEENPEHSYDKVGTYTVKLKVTDDKGESSVSTTTAEIKDLSENKLPVIYMHVPKSGALNQKVVFYGKGTYDPDGSIAGYQWDFGDGSDFSSEQNPSHVYTKKGEYTVTLRVMDSSGQMSEKTMKIKITDPVYPIGTEKEPNNSKETASGPIVPGIPVSGTIENTSDQDYFYFDVITPGEVKIDINKLGYGGATWVVYDENNNAVSYATDDGQNLSGKFKADKPGRYYIHLYMFNGSYMPYRINIEGSVGR
What is the function of this protein?
Clostridial collagenases are among the most efficient degraders of eukaryotic collagen known; saprophytes use collagen as a carbon source while pathogens additionally digest collagen to aid in host colonization.  Has both tripeptidylcarboxypeptidase on Gly-X-Y and endopeptidase activities; the endopeptidase cuts within the triple helix region of collagen while tripeptidylcarboxypeptidase successively digests the exposed ends, thus clostridial collagenases can digest large sections of collagen (PubMed:3002446).  The full-length protein has collagenase activity, while both the 116 kDa and 98 kDa forms act on gelatin (PubMed:7961400).  In vitro digestion of soluble calf skin collagen fibrils requires both ColG and ColH; ColG forms missing the second collagen-binding domain is also synergistic with ColH, although their overall efficiency is decreased (PubMed:18374061, PubMed:22099748).  Digestion of collagen requires Ca(2+) and is inhibited by EDTA (PubMed:9452493).  The activator domain (residues 119-388) and catalytic subdomain (330-601) open and close around substrate allowing digestion when the protein is closed (PubMed:23703618).
What are the official names of this protein?
Collagenase ColH, Class II collagenase, Gelatinase ColH, Microbial collagenase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M9B family. Collagenase subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: KDPC_CAUSK
Sequence: MLSHLRPAIVSAGLFTVLLGLAYPLAVTGVAQAAFPAQANGSLVKDAKGTVVGSTLIAQAFAKPEYLHPRPSAAGAGYDASASSGSNMGPLNDTLIKREKTDADALRAENPGVVIPADAVTTSGSGLDPEISPANARFQAPRVAKARGLRLAQVQAVIDGQAQGPLLGFIGQPRVNVLTVNRTLDARFPAHGQKGG
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: ARF4_BOVIN
Sequence: MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERIQEGAEELQKMLQEDELRDAVLLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNELSKR
What is the function of this protein?
GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase.  Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity).
What are the official names of this protein?
ADP-ribosylation factor 4.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
What are the subcellular locations of this protein?
Golgi apparatus. Membrane; Lipid-anchor.
Protein: PP230_ARATH
Sequence: MILRRLVLSATSNSNPRRSQSLSSSGVRILSSSSSDRYTSSSQRYSGDDRLARLRHKDWLAPNEVLKIFDNVKDPSFLLPAYQHYSKRKDYQPTESLYALMINKFGQAKMYDEIEEVMRTIKLEKRCRFSEEFFYNLMRIYGNLAGRINRAIEILFGMPDFGCWPSSKSFNFILNLLVSAKLFDEIHKIFVSAPKLGVEIDACCLNILIKGLCESGNLEAALQLLDEFPQQKSRPNVMTFSPLIRGFCNKGKFEEAFKLLERMEKERIEPDTITFNILISGLRKKGRVEEGIDLLERMKVKGCEPNPGTYQEVLYGLLDKKRNLEAKEMMSQMISWGMRPSFLSYKKMVLGLCETKSVVEMDWVLRQMVNHGFVPKTLMWWKVVQCVVSKNNDDSQANLDRITAC
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At3g14580, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SYR_COLP3
Sequence: MNIKNILSERVSAAMVAAGLPEGTNPAISLSNRPQFGDYQANGVMGAAKKLKTNPRELATKVVAELDLDGIASKIELAGPGFINIHLDESWLAAQLNEVAQDDFIGVAQRGTTPGDESQTVVVDYSAPNLAKEMHVGHLRSTIIGDAVVRALEFRGDKVIRQNHMGDWGTQFGMLIAHLSDKLASDEVAETALADLENFYREAKVRFDNEEGFADRARADVVKLQSGDEACAKLWQQFIDISITHSEEIYAKLNVSLKRSDIMGESAYNDDLSTVVDELMAKKIAEESQGAKVVFINEMANKDGEAPVFIVQKSGGGFLYATTDLSACRYRSGKLAANRIIIFTDARQALHFKQVEIVARKAGLLPENVGYQHCPFGMMMGDDGKPFKTRTGGTIKLAELLDESIVRAAALIKEKNPDITDTDLTEISKKVGIGAVKFADLSKNRTSDYIFDWKTMLSFEGATAPYLQYAYSRIQSIFSKAGTVKNDAVINIIEPQEKALALKLLQLEDVVDAVISECTPNLLCNYLYELASLYMSFYEACPILKEGISGEVKASRLALCNVVADTLKQGLDILGIETMERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECF_YERP3
Sequence: MALTRLLIKDFRNIESADLALAAGFNFLVGPNGSGKTSVLEAVYTLGHGRAFRSLQAGRVIRHECAEFVLHGRVDANEREASVGLSKSRQGDTKVRIDGTDGHKVAELAQMLPMQLITPEGFTLLNGGPKFRRAFLDWGCFHNEPGFFTAWSNLKRLLKQRNAALRQVSRYTQIRAWDQEIIPLAERISEWRAAYSDAIAADISATCALFLPEFALSFSFQRGWDKESDYGELLERQFERDRALTYTAVGPHKADFRIRADGTPVEDLLSRGQLKLLMCALRLAQGEFLTRQSGRRCLYLLDDFASELDTGRRRLLAERLKATQAQVFVSAVSAEQVADMVGEKGKMFRVEHGKIEVQPQD
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAI_EMIHU
Sequence: MSASFLPSILTPVVTLVFPGLMFALFFVLIEQEEIA
What is the function of this protein?
May help in the organization of the PsaL subunit.
What are the official names of this protein?
Photosystem I reaction center subunit VIII, PSI-I.
What is the protein family that this protein belongs to?
Belongs to the PsaI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: ACPS_SINMW
Sequence: MIIGIGSDLIDIRRIENSLQRFGERFVNRCFTDIEIAKSDGRKNRAASYAKRFAAKEACSKALGTGLAQGVFWKEMGVVNLPGGKPTMQLTGGAAARLREMLPVGHRAAIHLTITDDFPLAQAFVIIEALPVAPAEGTV
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_CLAM3
Sequence: MSIEINNESAIEVDEPVIQRLVTYALDTLHVHPDAELAIVMVDEGAMEQLHVQWMDEPGPTDVLSFPMDELRPGTEDRPTPAGLLGDIVVCPQVAAEQAVTAGHSTMEEILLLTAHGILHLLGFDHAEPDEEREMFGLQRDILIGFAMSERGR
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU1_SYNAS
Sequence: MDSPEKRIYIFDTTLRDGEQSPGSSMNPAEKLRIARQLEKMGVDIIEAGFPIASEGDFLSVQQIAQEIRGAQIAGLARANNADIDRAWEAIRDAANPRIHTFISSSDIHLKYQLRKSREQVLKEAVAAVERARSYTPNVEFSPMDATRTDRGYLCEMVEAVIAAGASTVNIPDTVGYAIPQEFGELIAYLRANVPNISQAIISVHCHNDLGLAVANSLSAILNGARQVECTINGIGERAGNTAMEEVVMALRTRKDLFGFYTGIKTESIYQSSRLLTQITGVAVQPNKAIVGANAFAHESGIHQDGLIKEKITYEIMTPQSVGISDSHIVLGKHSGRHAVSEHLKKLGFNLSDTELNKIFVRFKELADAKKNVFDEDLEAIVYEELYRVEDKYKLIYLNVVSGNVAIPTATMQMEVDREIVQDAGFGVGPVDATFDAIRKITGTNYDLLRYVVNAISGGTDAQGEVTVQLKFNGRSVVGHGADLDVIVASARAYINALNRLEFLKRDAGKIKSEYE
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: U119A_RAT
Sequence: MKVKKGGGGTGPGAEPVPGASNRSVEPTREPGAEAESGSESEPEPGPGPRLGPLQGKQPIGPEDVLGLQRITGDYLCSPEENIYKIDFVRFKIRDMDSGTVLFEIKKPPVSERLPINRRDLDPNAGRFVRYQFTPAFLRLRQVGATVEFTVGDKPVNNFRMIERHYFRNQLLKSFDFHFGFCIPSSKNTCEHIYDFPPLSEELISEMIRHPYETQSDSFYFVDDRLVMHNKADYSYSGTP
What is the function of this protein?
Involved in synaptic functions in photoreceptor cells, the signal transduction in immune cells as a Src family kinase activator, endosome recycling, the uptake of bacteria and endocytosis, protein trafficking in sensory neurons and as lipid-binding chaperone with specificity for a diverse subset of myristoylated proteins.  Specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization.  Binds myristoylated GNAT1 and is required for G-protein localization and trafficking in sensory neurons.  Probably plays a role in trafficking proteins in photoreceptor cells.  Plays important roles in mediating Src family kinase signals for the completion of cytokinesis via RAB11A.
What are the official names of this protein?
Protein unc-119 homolog A, Retinal protein 4, rRG4.
What is the protein family that this protein belongs to?
Belongs to the PDE6D/unc-119 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=ocalizes to the centrosome in interphase cells and begins to translocate from the spindle pole to the spindle midzone after the onset of mitosis; it then localizes to the intercellular bridge in telophase cells and to the midbody in cytokinetic cells.
Protein: TYPH_YERPE
Sequence: MFLAQEIIRKKRDGQPLSEEEIRFFINGIRDNVVSEGQIAALAMTIYFHDMSMPERVALTMAMRDSGTVLNWKSLNLNGPLVDKHSTGGVGDVTSLMLGPMVAACGGYVPMISGRGLGHTGGTLDKLEAIPGFDIFPDDNAFRKIIQNVGVAIIGQTSSLAPADKRFYATRDITATVDSIPLITASILAKKLAEGLDALVMDVKVGSGAFMPTYSLSADLAQAIVGVANGAGCKTTALLTDMNQVLASSAGNGVEVREAVRFLTGEYRNPRLLEVTMALCVEMLLSGGLAHDEADARAKLQAVLDNGKAAEVFGRMVAAQKGPADFVERYDSYLPVATLSKPVFAEQTGIITAMDTRALGMAVVALGGGRRRATDPIDYSVGLTEMARLGTRVDGQQPLAVIHANNEDDWQQEAEVVRAAITLGNNTPEETPVIYRRITE
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: Y202_ENCCU
Sequence: MSITSIPQPHETNEQHHTEIQHHRSAILNNDLVVLISIAFSALLYFIFDKDNFEKNPCLRLITTLFPLSYLAAQHLLLFHTSWKGNNKPEDTLHKALRYFFSALFITFATIFILSIIILTNDNWSKDDDPLFFSIVLPSFFIPPTYLLSISCSLVPGQTGFTDTGINILIDVLILLCFIVNFIFMHEKSKYRLYSAVTFPLLVLVRLLTEKYYPSGKSSLPTTTWRVVAFVLIFILVIYTYTDMGCEAILTLDYYFTYLTR
What are the official names of this protein?
UPF0328 protein ECU02_0020/ECU04_1700.
What is the protein family that this protein belongs to?
Belongs to the UPF0328 family.
Protein: HENMT_BOMMO
Sequence: MIIAIQTLIFFRQSLLTALDRLLRPYFQKFALSLTKSSFESDDDEPDENVFAEYDDEKGVIFFPPMYVQRYAAIVDCLLDERWSGKLDKVVDLGYHDMSFIKYLKEVSGIKSILGVDLETIPLQCSSDLLSCNEYAPKRETPLQISLLQGNAADPDYRLIGCDAVIAIEMIEHMLPHDLERLVHTVFAFIKPWIVIFTTPNDFKDVITGDINICKFNEKYLHRLNCTTLQVKKFSKTTQGLMAKNKVDALVHTREVVEEIKHLTKMLNFNKSGLNQQDEKTHIWYNFNWGENAPYWNQYYKIVREYNYPFETKSDDCRILDLISDEMNRLIDLQYDDILSVDLNKLEIPLQHLMQTVQHITDDVENVRELLEWNGYEVVDDMVIYSRLAIDNVTIDSQIDDWQENESVSDVKKFN
What is the function of this protein?
Methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements.  This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation.  Stabilization of piRNAs is essential for gametogenesis.
What are the official names of this protein?
Small RNA 2'-O-methyltransferase, HEN1 methyltransferase homolog 1, BmHen1.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. HEN1 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Component of the meiotic nuage, also named P granule, a germ-cell- specific organelle required to repress transposon activity during meiosis.
Protein: LCK_AOTNA
Sequence: MGCGCSSHPEDDWMENIDVCENCHYPIVPLDGKATLLFRNGSEVRDPLVRYEGSNPPASPLQDNLVIALHSYKPSHDGDLGFEKGEQLRILEQNGEWWKAQSLTTGQEGFIPFNFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITFPGLHELVRHYTNASDGLCTRLSRPCQTQKPQKPWWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNDHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYHLMMLCWKERPEDRPTFDYLRSVLEDFFTATEGQYQPQP
What is the function of this protein?
Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T-cells in the thymus and in the function of mature T-cells.  Plays a key role in T-cell antigen receptor (TCR)-linked signal transduction pathways.  Constitutively associated with the cytoplasmic portions of the CD4 and CD8 surface receptors.  Association of the TCR with a peptide antigen-bound MHC complex facilitates the interaction of CD4 and CD8 with MHC class II and class I molecules, respectively, thereby recruiting the associated LCK protein to the vicinity of the TCR/CD3 complex.  LCK then phosphorylates tyrosine residues within the immunoreceptor tyrosine-based activation motifs (ITAM) of the cytoplasmic tails of the TCR-gamma chains and CD3 subunits, initiating the TCR/CD3 signaling pathway.  Once stimulated, the TCR recruits the tyrosine kinase ZAP70, that becomes phosphorylated and activated by LCK.  Following this, a large number of signaling molecules are recruited, ultimately leading to lymphokine production.  LCK also contributes to signaling by other receptor molecules.  Associates directly with the cytoplasmic tail of CD2, which leads to hyperphosphorylation and activation of LCK.  Also plays a role in the IL2 receptor-linked signaling pathway that controls the T-cell proliferative response.  Binding of IL2 to its receptor results in increased activity of LCK.  Is expressed at all stages of thymocyte development and is required for the regulation of maturation events that are governed by both pre-TCR and mature alpha beta TCR.  Phosphorylates other substrates including RUNX3, PTK2B/PYK2, the microtubule-associated protein MAPT, RHOH or TYROBP (By similarity).  Interacts with UNC119; this interaction plays a crucial role in activation of LCK (By similarity).
What are the official names of this protein?
Tyrosine-protein kinase Lck, Lymphocyte cell-specific protein-tyrosine kinase, Proto-oncogene Lck, p56-LCK.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytosol. Note=Present in lipid rafts in an inactive form.
Protein: MDM12_LACTC
Sequence: MSFEINWQDLGEDEAVNDSIKSFLNSHLQSISLPSYVSSLQVTDFCLGGIPPNITLREISDPLDEFYNHIEKEELPKDKIPEESDSGCQSADGENGDLLPEVQAESDLQFLVEVDYKGDMRIGVSAELALNYPSPSFMTLPVKLSITDLGIHALCLVAYISKQLFVSFLCDVADPILDARESLIDLGSSAILGKKSLERISLIRSIKIDSEIGEQNNVEGSVLRSVGKLEQFLLEVFRTILKKEAAWPSWINLDFNEDPSGNESSDED
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.  The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 12, Mitochondrial inheritance component MDM12.
What is the protein family that this protein belongs to?
Belongs to the MDM12 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: UXUB_ECOLI
Sequence: MTTIVDSNLPVARPSWDHSRLESRIVHLGCGAFHRAHQALYTHHLLESTDSDWGICEVNLMPGNDRVLIENLKKQQLLYTVAEKGAESTELKIIGSMKEALHPEIDGCEGILNAMARPQTAIVSLTVTEKGYCADAASGQLDLNNPLIKHDLENPTAPKSAIGYIVEALRLRREKGLKAFTVMSCDNVRENGHVAKVAVLGLAQARDPQLAAWIEENVTFPCTMVDRIVPAATPETLQEIADQLGVYDPCAIACEPFRQWVIEDNFVNGRPDWDKVGAQFVADVVPFEMMKLRMLNGSHSFLAYLGYLGGYETIADTVTNPAYRKAAFALMMQEQAPTLSMPEGTDLNAYATLLIERFSNPSLRHRTWQIAMDGSQKLPQRLLDPVRLHLQNGGSWRHLALGVAGWMRYTQGVDEQGNAIDVVDPMLAEFQKINAQYQGADRVKALLGLSGIFADDLPQNADFVGAVTAAYQQLCERGARECVAAL
What are the official names of this protein?
D-mannonate oxidoreductase, Fructuronate reductase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family. UxuB subfamily.
Protein: DYTN_HUMAN
Sequence: MDPDKQDALNSIENSIYRTAFKLQSVQTLCQLDLIDSSLIQQVLLRPSFWEARKHSLSVQQLSQALQELFQKAREENPGQVHPRAPELTLSLLTTMYNSKGTGFLQLMPAAAALITLSGDSPLSKYRALFQLYAENSRGGYDSGPRMTRRVLRKLLTDLQQIPTFVGESRALCPVESATRSCFQGVLSPAIKEEKFLSWVQSEPPILLWLPTCHRLSAAERVTHPARCTLCRTFPITGLRYRCLKCLNFDICQMCFLSGLHSKSHQKSHPVIEHCIQMSAMQNTKLLFRTLRNNLLQGRCRKKEAARRQQLLDQVNPKGVPHHAQARLLKKQLNQYKDKLQAIYTSQEERICRFETRIHKLKTNQDSLWTKLQQIRRDLQARLQPPGPSSSSFQNVGNKVDHSSTEKVPKGGDYLQIKNATEDASTGEPLPKLDEVDRSHRSHTNAEHALRNPESPETTLHSTRAQSQTQKMPQKVISALPSYQEGLKQDIPKMVPAEMSSPALAAVEKKEAGNIKERKDELEEEELQELLSKLMDAFNLETPSGPESSVNMDLYSGAQRVCRAFSALVDQIALPNLK
What are the official names of this protein?
Dystrotelin.
What are the subcellular locations of this protein?
Cell membrane.
Protein: GATC_BACAA
Sequence: MSRISVENVKHVAHLARLAITDQEAEKFQKQLDAIVTFAEQLNELDTTDVKPTTHVLTMKNVMREDVPEKGLPVEEVLKNAPDHKDNQIRVPAVLE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: RL6_COLP3
Sequence: MSRVAKAPVVVPAGVTITLSGQDITVKGPIGELSRTIHSDVVVSQEENNIITNIVADVKGAWAQAGTTRALINNMVEGVSKGFEKKLVLQGVGYRAKAAGKSLDLSLGFSHPIKHAIPEGITCETPSQTEVTLKGCDKHLVGQTAANIRAYRKPEPYKGKGVRYVDEYVRRKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: PROP1_THEGE
Sequence: MEAERRRQAEKPKKGQVGSSLLPERHPAAGTLTTMVDSSAPPCRRLPGAGVGRPRFSPQGGQRGRPHSRRRHRTTFSPVQLEQLESAFGRNQYPDIWARESLARDTGLSEARIQVWFQNRRAKQRKQERSLLQPLAHLSPAAFSSFLPESSACPYSYAPPPPPVTCFPHPYSHALPSQPSTGGAFALPHQSEDWYPTLHPTPAGHLPCPPPPPMLPLSLEPSKSWN
What is the function of this protein?
Possibly involved in the ontogenesis of pituitary gonadotropes, as well as somatotropes, lactotropes and caudomedial thyrotropes.
What are the official names of this protein?
Homeobox protein prophet of Pit-1, PROP-1, Pituitary-specific homeodomain factor.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RSMG_HALHL
Sequence: MPRKYLESRLEDLQIELDAPALERLEGFLSLLMRWNRAYNLTAARDVETLIDRHLLDSLVVRRYLPAGALADVGSGAGFPGLVLALIEPDRSVTLIDSNGKKTRFLRQCATELGLHRVQVRQARMEALDDGDFAVVTARAVAPLATLIPGTRGLLAPDGALLALKGERIQEELAELPEALVEALDVHELPAIAGQGRACLVACRAAVHL
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1276_ARCFU
Sequence: MRAAIAVLFIALVGLATYHLVMSQANPELRTVDIEGKKLILRGFENPAVKVKGCGEEALLHGSIVEIPLNCSKVKVEVYSEGRLVFSSSLSLNP
What are the official names of this protein?
Uncharacterized protein AF_1276.
Protein: RL15_SODGM
Sequence: MRLNTLSPAEGSKHASKRPGRGIGSGLGKTGGRGHKGQKSRSGGGVRRGFEGGQMPLYRRLPKFGFTSRKSMVTAEIRLSDLAHVEGDVVDLNTLKAANIVGIQTEFAKIMLSGEVKRAVTIRGLRVSKGARAAIEAAGGKIEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: F16A3_CUPNH
Sequence: MPEVQRMTLTQFLIEERRRYPDASGGFNGLILNVAMACKEIARAVAFGALGGLHGKASTQAGEEGAVNVQGEIQQKLDVLSNTTFLRVNEWGGYLAGMASEEMEAPYQIPENYPRGKYLLVFDPLDGSSNIDVNVSVGSIFSVLRAPEGADTVTEQDFLQPGSAQVAAGYALYGPTTMLVLTVGNGVNGFTLDPNLGEFFLTHPHLRVPPDTQEFAINASNSRFWEAPVQRYIGECMAGKSGPRGKDFNMRWIASMVAEAHRILMRGGVFMYPRDTKDPAKPGRLRLLYEANPIAFLMEQAGGRASTGRQTLMSVAPGALHQRIGVIFGSRNEVERIEGYHTNQTDPDLPSPLFNERSLFRASA
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1 3, FBPase class 1 3, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 3.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.