Protein: HTS1_COCCA
Sequence: MTMPHHSSGPAKDSPLCRFPPFPGGNPVFTNIRREKVNFQLPPPDHALLAAAWAVLLRLYTGHVKTCFESATSDQEANLVTYEARDSDTLQTIVLRGACVSSTAEEKAGLRDLNTAVVRTTVSIDSWTDEMLQDKIAALLQPGKEIVLFQTPSGCVLVYMQSFMSAMEVKNVSSTLTYIMSSDPDKTAIRNLSISPRDLAQIMRWNDRKLKSERTNLVYDLFSARAHEQDANMAIDAWDGRMSYTELERVSSTWARQLQKQGISQGSWVLFCFEKSRLAVVSMIAILKAGGVCVPIDPRYPVERIRDIIRTTNATIALVGAGKTAALFKSADTAVQTIDITKDIPHGLSDTVVQSNTKIDDPAFGLFTSGSTGVPKCIVVTHSQICTAVQAYKDRFGVTSETRVLQFSSYTFDISIADTFTALFYGGTLCIPSEEDRMSNLQDYMVSVRPNWAVLTPTVSRFLDPGVVKDFISTLIFTGEASREADTVPWIEAGVNLYNVYGPAENTLITTATRIRKGKSSNIGYGVNTRTWVTDVSGACLVPVGSIGELLIESGHLADKYLNRPDRTEAAFLSDLPWIPNYEGDSVRRGRRFYRTGDLVRYCDDGSLICVGRSDTQIKLAGQRVELGDVEAHLQSDPTTSQAAVVFPRSGPLEARLIALLVTGNKDGTPHNQQSLPKPAFAQCPPDLVKYATSSLQQRLPSYMVPSVWLGIDFLPMSVSGKLDRAVLQDQLESLSPSDYAEILGTTGLEVDPGGAASSVASDSDLRDMNDDSLLLTACSRVLNLPAGKISYSQSFIHAGGDSITAMQVSSWMKRFTGKRIGVKDLLVSPSISTAASCIKSAQDGSRNFVAVRPGQRIPVSPIQKLFFQTAEASKSWNHYHQSFLFRIDQPIKPQTIEDAISLVMQRHPMLQARFERTEEGDWYQYIPIDVERRASVEVIGSLSTDDREAAMLRARQSIDLTEGPLIRCQLFNNNVDEASRLFFVVIHHAVVDLVSWRIIMEELEAHLATDSTPDRGEAYQESVPFLAWCQVQAEAVKDIPVDRTVPLIPKIPTADFGYWGLKHDENVYGNTVERKIPLGHSITEDLLYKCHDSLHTKTIDVLLAAVLVSFRRSFLDRPVPAVFNEGHGREPGGEDAVDLSRTVGWFTTISPVYVPEVSPGDILDVVRRVKDYRWATPNNGFDYFSTKYLTQSGIKLFEDHLPAEILFNYEGRYQAMESEQTVLKPESWHAGEASKDQDPGLRRFCLFEISTAVLPDGQLHLTCSWNKNMRHQGRIRLWLDTLLPAAIGEIVSSLALASPQLTLSDVELLRLYDYSSLDILKKSILSIPAVQTLDDLEGVYPGSPMQDALFLSQSKSQDGAYEVDFTWRVATSLQNSQPAVDIGCLVEAWKDTVALHAALRTVILESSLPATGILHQVVLRSHDPDIVILDVRDVTAAITILDSYPPPTEEGIALIKRPPHRLLICTTIEGSVLIKFQVNHLVFDGMSTDKIIQDLSKAYTCRHSNKLPDHSESKLHDGTYGNRPTKPPLAEFIRYIRDPQRKQDSINYWKNALRGATTCSFPPLFDQITSEKAMPRQSWASVPIPLCVDSKELSKTLANLGITMSTMFQTVWAIVLRIYSQNGQSVFGYLTSGRDAPVDGIDSAVGNFIAMLVCFFDFDDDGVHTVADMARKIHNASANSISHQACSLAEIQDALGLSTSTPLFNTAFTYLPKRPTNVKAGEPEHHLCFEELSMSDPTEFDLTLFVEPTQESNEVSAHLDFKLSYISQAYATSIASTVAHILSELVHDPYRALNTLPIVSEHDTAIIRSWNDHLFPPATECIHETFSRKVVEHPQREAICSWDGSLTYAELSDLSQRLSIHLVSLGIKVGTKIPICFEKSMWTIVTILAVVQAGGVFVLLEPGHPESRLSGIIKQVQAELLLCSPATSRMGALQNISTQMGTEFKIVELEPEFIRSLPLPPKPNHQPMVGLNDDLYVVFTSGSTGVPKGAVATHQAYATGIYEHAVACGMTSLGAPPRSLQFASYSFDASIGDIFTTLAVGGCLCIPREEDRNPAGITTFINRYGVTWAGITPSLALHLDPDAVPTLKALCVAGEPLSMSVVTVWSKRLNLINMYGPTEATVACIANQVTCTTTTVSDIGRGYRATTWVVQPDNHNSLVPIGAVGELIIEGSILCRGYLNDPERTAEVFIRSPSWLHDLRPNSTLYKTGDLVRYSADGKIIFIGRKDTQVKMNGQRFELGEVEHALQLQLDPSDGPIIVDLLKRTQSGEPDLLIAFLFVGRANTGTGNSDEIFIATSTSSLSEFSTVIKKLQDAQRAMEVLPLFMVPQAYIPIEGGIPLTAAGKIDRRMLRKLCEPFNRNDLISFTSKALSTSVKDAETTDTVEDRLARIWEKVLGVKGVGRESDFFSSGGNSMAAIALRAEAQRSGFTLFVADIFTNPRLADMAKLFSHGQSVSPSSSTLRTKVPISSLQKRSSGLQTAAPVSNGSPVRRCQKENIIDCPVAFEYEEGPSDTQLKEASRICGISSRSIEDVFPCTPMQEALVALSLIPGAQASYALHAAFELRPGLDRNRFRSAWESTVKAQPILRSRIISGSNGSSVVVTSATDSIPQLDVSGLDTFLEQQLQVGFAPGAPLFRLAFVYSKADDCDYFVISAHHAIYDGWSLNLIWSQVLALYTNGELPPPGPSFKHFARNLNLVQSKLDSEDFWRKLLVKPDQESFRFPDVPVGHKPATRCTTNFHFPFSMQSKIGTTANTCINAAWAITLAQYSSNKTVNFGVTLWGRDFPMIDIEHMTGPTIVTVPRQVNVIPESSVAEFLQDLQKSLAVVLPHQHLGLHRIQALGPIARQACDFSTLLVVNHGSSISWSELEAADIVPVPLRSSDLYAYPMVVEVENASSDTLDIRVHSDPDCIEVQLLERLMEQFGHNLQTLCRAASFDPGKRIAELMDDTATTHLRTLFSWNSRVKDSPDVAAIAVHKLLEETAQSQPAESAIVAHDGQLSYMQMDRCADVLARQIRKTNMISAQSPFVCIHLLRSATAVVSMLAVLKAGGAFMPVDISQPRSRLQNLIEESGAKLVLTLPESANALATLSGLTKVIPVSLSELVQQITDNTTKKDEYCKSGDTDPSSPAYLLYTSGTSGKPKGVVMEHRAWSLGFTCHAEYMGFNSCTRILQFSSLMFDLSILEIWAVLYAGGCLFIPSDKERVNNLQDFTRINDINTVFLTPSIGKLLNPKDLPNISFAGFIGEPMTRSLIDAWTLPGRRLVNSYGPTEACVLVTAREISPTAPHDKPSSNIGHALGANIWVVEPQRTALVPIGAVGELCIEAPSLARCYLANPERTEYSFPSTVLDNWQTKKGTRVYRTGDLVRYASDGTLDFLGRKDGQIKLRGQRIELGEIEHHIRRLMSDDPRFHEASVQLYNPATDPDRDATVDVQMREPYLAGLLVLDLVFTDEVMGIPCTSLTSANTSENLQTLVTELKKSLRGVLPHYMVPLHFVAVSRLPTGSSGKLDHAFVRACLRELTAPLDGNFPKVEQVLTTNESVLRQWWGTVLAMDPHSIQRGDDFFSLGGSSISAMRLVGLARSSGHKLQHEDIFMCPRLADMAGQISFVQEASVSPTTSPTIKFDLLDDCEVDEVIDHILPQLDMNKELIEDVYPCTPLQESLMAATARHGEAYTMIQSITVLASQLAQLKKAMDVVFRDFEVLRTRIALGPSQQALQVVVKHEELSWESFPSIQSFKDHFYRSLGYGKPLARLAVITQALDTKQPISHGTREARTKNSQDTVMVVVGAHHSIYDAHVLSMIWRRLYREFIGSQADGILEAETSRSEGVVPFKSYVEKLLRGKDNDESLLFWKEKLRGVSSSQFPPASWPRVLEHQPSATQTLITKVSLPTSSRKKLGATVATVAYAAWALTIAHYTADPDVVFGATLSGRETMAGSISHPESIAGPTIITVPLRIIIDFQTVVSDFLSTLQKDIVRAAYFGQMMGLNSIAHIDNDCRDACGFKSIIVVQVPDEGENHDGRAANPFQMSLESIGHFPAPLVVEVEQSESTDVLIRMAYDPVLVPEKLAHFISDTFTTTMSNLSAANPKAKVESIPALSEAHLAELDVTCPEWILGKAKDEKIRTESHQCLQDLVCRRAQQSPNSQAIDSWDGSISYHELDGLSSILAEHLSQLGVRPEAPVCLLFEKSKWAVVAMIGIIKAGGCFVPLDPSYPHERLEHIISETGSSVIVTSAAYSKLCLSLSVRGIVCDGSVFSSTKKPLPSTADSPPSFSVRPNQAAYILFTSGSTGKPKGVVMEHHSVCSALIALGKRMGLGPQSRVLQFNSYWFDVMLLDIFGTLVYGGCLCIPKEEQRMSNLSGWVQKFKVNTMLLSTSVSRLMQPADTPSLETLCLTGEAVLQSDVDRWAPKLHLIAGYGPTETCIMSVSGELTPSSPANLIGKPVSCQAWVINPLKETELAPYGATGELYIQGPTVARGYLHDDVLTSKAFIVDPQWLTGYKTNENQWSRRAYKTGDLVFWGPQSNLYYVRRKDSSQVKIRGQRVELAEIEEVIRQHIPPDVTVCVDLLSSDDQNTRIILGAVLGIGDRALGGPEDLEVIGYMDDLKSHIIPALEASLPHHMIPEAYVPFVQLPTLGSGKLDRKTVRRVAGPLAFSLPQASARHPNQPTVTHTQKLLRQLWCKILPQLDESAVNKQDNFLGIGGDSIAAIKLVALLRQHGISLAVAEIFTRPTLEAMSSLIDEHNFVVSHAGILSDVTRNTSGVMRQTTNLIAGRHSMAVEKSRECDNSTLPCTEYQQMFLAGTEAFTGAHSAQFIFRLPEKIDLDRLQAAFDHCADWYPNLRTQIHKDADTGRLLHDISPIGVKVPWSCHYSDDLNTVLSHDKKFPPGLDGPLHRVTIMRHRDPTESMLVWTLNHAAYDAWSLRMMLEHITEAYANPDYEPSYSLGWTAFVLHTENTKEASRSFWSSYLSDVKPARLMFNYNLVSNPRQDRLYEARINIPKRVLSQATAATVLLAGLTLLVARVCDTRDVILAHLLTGRTLPLAGIENCPGPTITKVPLRIPLMDQDLVTLELDSVAKKITAELMRVMPHEHSGLSAIREFIPQAEGTTTSSGKFHAGSVLGRLPLDLVIHPKGGLDLLGKHGLGLQNEGFRLVAPPSGGLSMECALVDDDDDKRSDTISVDVSVLWDQRAATQEDVIELVHSLQGIFTKRNLAASICLMYK
What is the function of this protein?
Non-ribosomal peptide synthetase, able to activate proline and AEO (2-amino-9,10-epoxi-8-oxodecanoic acid), and epimerize L-Pro.  Catalyzes the production of HC-toxin: a cyclic tetrapeptide.  Activates and thioesterifies L-Pro, and epimerizes it to D-Pro; also uses D-Ala as a substrate but this is epimerized from L-Ala by TOXG.
What are the official names of this protein?
HC-toxin synthetase, HTS.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.