PharMolix/UniProtQA huggingface dataset:
Protein: MOT12_XENTR
Sequence: MTQEKRNLHKAPPDGGWGWMIVIGCFFVTVCTRAVTRCISIFFVEFQSYFAQDYARTAWIHSIVDCSTMLCAPIGSYVSNHFSCQVGIILGGVLASTGLVLSSFATSLEYLYLTLGVLTGLGFALCYSPAIAMVGKYFEKRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVSNLCVCGALMRPITLKEDSLHYPLKQEQMENEPTQSGRLDSSCSPLCQDCSHKRLCYCTKKEYSFLLKPKFMVLAVSFLFLAYGCSPPFVYLVPYALNVGVSNQEAAFLMSILGIIDIVGNITFGWVTDTRFLKKHRYCCYLIAVGLDGLCCLFLPILTRFQLLVPFSVMFGYFDGAYVALIPVVTGDVVGTSSLSSALGVVFFLHAVPYLVSPPIAGWLVDTTGDYTAAFLLSGFSMIFCAVLLALAKIINRIKKRPKAVAVPTSDIKQEIWTNGDVSCANAINQKEV
What is the function of this protein?
Functions as a transporter for creatine and as well for its precursor guanidinoacetate.  Transport of creatine and GAA is independent of resting membrane potential and extracellular Na(+), Cl(-), or pH.  Contributes to the process of creatine biosynthesis and distribution.
What are the official names of this protein?
Monocarboxylate transporter 12, MCT 12, Solute carrier family 16 member 12.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PTH_DESVH
Sequence: MNISGLIIGLGNPGREYDRTRHNFGFMFIDALLEEAQRNPFARCEQLSGGKKKYDLWRCDIVEGQAPWLLAKPQTFMNLSGEAVLAIASFYRVKPAAMVVAHDELDLPLGRMRFKMGGGNAGHNGLKSITQCLGTPDFHRLRLGIGKPPAGGETTGWVLGRFSQSDTAMVDAVLEAAIQGIRTFATEGDVAATQYINAFRP
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUF1_LEIMA
Sequence: MKLCGVRGSGVSLMRSSNFPCFRAAHNGGAPTATRHQSLCGRCLDSHMGAGKRWCFRPLLAEPRRYGSASSASTTDAATAPVHGEDLYVSHYAIPEDARRLVGTPQLLPRNPAEEVAFKKNLIRSFPQACIRNVSVVAHVDHGKTTLSDAMLRFSNLLPADGATGTFTDRLKVEKERGITIKAQTCSVLLTVRETGTQYLVNLIDTPGHVDFQYEVSRSLCASEGAALLVDVRQGVEAQTMAQFYAALEQNLTILPVLTKMDNVMSDAEVEKTLLQLEDSTGLLSREVILTSAKSKQGIEQLFQQIIDKVPPPRGREGFSDMKQLPAMHPDSADRKKVEKELVPLRALLFDCWTSESSGMTDGAASAPVSTVSSVSSGTTAASGGQSVAKDGIYGLIRVMDGTVTPGTTVTFFHSGKKHEVREVGIIHPTLHPTAALTAGMVGFVFFPGLLKKDVFIGDTLCTLPTRKHTMRVVATGPPETASRTKPATAAETASSDDASGSSGSSVVEPIPGFKTVQPVVFAGFYPDEGVYITQLREAVDLLCVNDPSVTVEQLQCPALGPGLQLGFLGFLHMQVFKERLLMEFGQTVLVTPPQVQYMYVEQHGDPDDPAQRKPVSVSNWRWPHEGVGAYLEPFITATVLTPSEYLNEINSAALSAFRGEMQEMRVIDGARTLVRYRMPLADLARGFFSTVKSSSHGYATLEYDDPTYMTADLVKMDIVINKAHISALSTICLRHEATTHARRIIGSLKENLLRSSVDLPLQALVGSKIIARETVKAYRKDVTAKIHAGDISRKQKKWNDQKKGKERMARRSVGTVTLDQSVLAAALGATTAR
What is the function of this protein?
Promotes mitochondrial protein synthesis.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Binds to mitochondrial ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Translation factor GUF1 homolog, mitochondrial, Elongation factor 4 homolog, EF-4, GTPase GUF1 homolog, Ribosomal back-translocase.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: CB29_CHLRE
Sequence: MVFKFPTPPGTQKKAGTTATKPAPKATTKKVATSTGTRSGGVGYRKYQGDALWLPNTTRPEWLDGSLPGDRGFDPLGLSKPSEFVVIGVDENDQNAAKNNKGSVEAIVQATPDEVSSENRLAPYSEVFGLARFRECELIHGRWAMLACLGALVAEATTGVSWVEAGKVELDGASYAGLSLPFSITQLIWIEVILVGGAEFYRNSETNPEKRCYPGGVFDPLKLASEDEERAFRLKTAEIKHARLAMVSFFGYGVQALSTGEGALGSLAKFADGLNNGKGL
What is the function of this protein?
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.  CP29 facilitates the State 1 to State 2 transition, where State I is induced by excess photosystem I (PSI) light and State 2 is induced by excess photosystem II (PSII) light.
What are the official names of this protein?
Chlorophyll a-b binding protein CP29, Lhcbm4.
What is the protein family that this protein belongs to?
Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: FLII_RHIME
Sequence: MAREAAEKTATSTSLAALAGLVERYANPDFAIAPGGHVQTISPGHYTVSGLSRHVRLGDFVAHKSTTGTHLGEVVRVEPERVVVCPIEPGDPIGIHDVVIRKGAFRIAPTDNWCGRTINALAEPIDGLGALLQGDIRRSIANTAPPSMTRKRVEQGFRTGVRAIDIFSPLCLGQRLGIFAGSGVGKSTLLSMLARADAFDKVVIALVGERGREVREFIEDTLGDNLSKSVAVVATSDESPMLRKMAPLTAVTIAEHYRDKGDNVLLIVDSVTRFAHAIREVATAAGEPPIARGYPASVFTELPRLLERAGPGAEGAGTITAIISILVDGDNHNDPVADSARGILDGHIVLDRSLAEEGRYPPVNPLASISRLARKAWTPDQEKLVARLKSLIHRFEETRDLRLIGGYRPGGDADLDMAIKQVPVIYDVLKQMPGERPAFDAFTDLANALKAAAMGNQPGAAGLRGRG
What is the function of this protein?
Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum.
What are the official names of this protein?
Flagellum-specific ATP synthase.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_GEODF
Sequence: MKMNLEKLGERIIEGGDILVEEALELANLRGSALYPLFGAASRIKEHFVGDKVFLCSIVNAKSGRCPENCSFCAQSAHHKTDAPVYSLIDEERMVACAREAEKNGSSCYGIITSGTSIKKGEELERICNAVRRIRRETGITPSCSLGIINHETASALVEAGVETYHHNLETSRSFFPNVCTTHDYEEDVNTVRVAKKAGLKVCCGGIFGLGESVAQRIEMAYTLRELDVDSVPLNFLNPIAGTKLENAENITPMECLQTIALFRLILPTKRISICGGREKNLRDLQSWIFFAGASGTMIGNYLTTTGRAAEEDWQMLKDLNLSVASCCE
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: RUVC_PAEAT
Sequence: MTLRVLGVDPGLTRCGIGVVDIEKNRRATMVAVGVVGTSAELTLDKRLLVIAQAIDEWLDRHEPDVVAVERVFSQMNVSTVMGVAQASGVVIAAAARRGIPVALHTPSEVKAAVTGSGTANKDAVTKLVTKILRLDAPPKPADAADALALALTHAWRAGSGMGAASGNSSLTPAQKAWADAEAKARRKR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: PO2F2_MOUSE
Sequence: MVHSSMGAPEIRMSKPLEAEKQSLDSPSEHTDTERNGPDINHQNPQNKASPFSVSPTGPSTKIKAEDPSGDSAPAAPPPPQPAQPHLPQAQLMLTGSQLAGDIQQLLQLQQLVLVPGHHLQPPAQFLLPQAQQSQPGLLPTPNLFQLPQQTQGALLTSQPRAGLPTQPPKCLEPPSHPEEPSDLEELEQFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAETMSVDSSLPSPNQLSSPSLGFDGLPGRRRKKRTSIETNVRFALEKSFLANQKPTSEEILLIAEQLHMEKEVIRVWFCNRRQKEKRINPCSAAPMLPSPGKPTSYSPHLVTPQGGAGTLPLSQASSSLSTTVTTLSSAVGTLHPSRTAGGGGGGGGAAPPLNSIPSVTPPPPATTNSTNPSPQGSHSAIGLSGLNPSAGPGLWWNPAPYQP
What is the function of this protein?
Unable to bind to the octamer motif, but can still activate the beta-casein gene promoter at low levels.
What are the official names of this protein?
POU domain, class 2, transcription factor 2, Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2, Octamer-binding protein 2, Oct-2, Octamer-binding transcription factor 2, OTF-2.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=In alveolus epithelial cells of mammary glands, present in the nucleus and cytoplasm. In HC11 mammary epithelial cells, present in the nucleus and preinuclear regions.
Protein: PSTB1_ENTFA
Sequence: MGKEIISSKDLHLYYGKKEALKGIDLTFNQGELTAMIGPSGCGKSTYLRCLNRMNDLIPDVTITGSVVYKGKDIYGPKTDNVELRKEIGMVFQQPNPFPFSVYENVIYGLRLKGVKDKQVLDEAVETSLKAAAVWEDVKDKLHKSALSLSGGQQQRVCIARVLAVEPDIILLDEPTSALDPVSSGKIENMLLTLKEKYTMIMVTHNMSQASRISDKTAFFLQGDLIEFNDTKKVFLNPKEKQTEDYISGKFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB 1, ABC phosphate transporter 1, Phosphate-transporting ATPase 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RS12_HYPNA
Sequence: MPTIQQLIRNPREPKRTRTKTPALKACPQRRGVCTRVYTTTPKKPNSALRKVAKVRMTSGFESLCYIPGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGALDTQPVKNRKQRRSHYGAKKPK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: OCTB2_DROME
Sequence: MLLCDGLGPEPPRQRHRNRTSAARIRKRPKCCCGDGGSGNQAEQPGGIVSNPISYGQSLTTLARVTAAALTTAAMLHTTNALAATGSSSASNSSTGGIALPLGTATPATHELNATQPFGGSGLNFNESGAGLSDHHHHQQHNPDEDWLDNIVWVFKAFVMLLIIIAAICGNLLVIISVMRVRKLRVITNYFVVSLAMADIMVAIMAMTFNFSVQVTGRWNFSPFLCDLWNSLDVYFSTASILHLCCISVDRYYAIVKPLKYPISMTKRVVGIMLLNTWISPALLSFLPIFIGWYTTPQHQQFVIQNPTQCSFVVNKYYAVISSSISFWIPCTIMIFTYLAIFREANRQEKQLMMRHGNAMLMHRPSMQPSGEALSGSGSSKTLTLHEVEQEHTPTKDKHLIKMKREHKAARTLGIIMGTFILCWLPFFLWYTLSMTCEECQVPDIVVSILFWIGYFNSTLNPLIYAYFNRDFREAFRNTLLCLFCNWWKDRHLPLDIDIRRSSLRYDQRAKSVYSESYLNSTTPSHRRQSQMVDNL
What is the function of this protein?
Autoreceptor for octopamine (OA), which is a neurotransmitter, neurohormone, and neuromodulator in invertebrates (PubMed:15998303, PubMed:21186359).  Essential for ovulation and fertilization (PubMed:25099506, PubMed:25353988).  During ovulation it mediates the OA-induced relaxation of the oviduct visceral muscles, by increasing cAMP levels and activating effectors such as calmodulin-dependent kinase II (CaMKII) and cAMP-dependent protein kinase A (PKA) pathways (PubMed:25353988).  Positively regulates synaptic growth; an action that is antagonized by Octbeta1R (PubMed:21186359, PubMed:22553037).
What are the official names of this protein?
Octopamine receptor beta-2R, DmOct-beta-12, DmOct-beta-2R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CSBB_BACSU
Sequence: MKQGLISIIIPSYNEGYNVKLIHESLKKEFKNIHYDYEIFFINDGSVDDTLQQIKDLAATCSRVKYISFSRNFGKEAAILAGFEHVQGEAVIVMDADLQHPTYLLKEFIKGYEEGYDQVIAQRNRKGDSFVRSLLSSMYYKFINKAVEVDLRDGVGDFRLLSRQAVNALLKLSEGNRFSKGLFCWIGFDQKIVFYENVERKNGTSKWSFSSLFNYGMDGVVSFNHKPLRLCFYTGIFILLLSIIYIIATFVKILTNGISVPGYFTIISAVLFLGGVQLLSLGIIGEYIGRIYYETKKRPHYLIKEANIPNKDLPETNELKSMRRLTKMH
What are the official names of this protein?
Putative glycosyltransferase CsbB.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. GtrB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PCRB_LISIN
Sequence: MKHLFKLDPAKNLPRNSVTKLIHSGTDGFIIGGTDNLEIEAVENLYELLAETDLPIFLEVSDESMILPEAEHFLIPVVLNTENSKWTHGLHKELIKELGDFIPWKRITSEGYVILNKDAKVAQLTEAKTDLTDEDIIAYARLAENIFRLPIFYVEYSGMYGDPEAVRKVSEVLSDTEFWYGGGIRSKEQAAEMAKYADTIIVGNIIYEDLEKALETATIFRKKTV
What is the function of this protein?
Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP).  This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales.
What are the official names of this protein?
Heptaprenylglyceryl phosphate synthase, HepGP synthase, Glycerol-1-phosphate heptaprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GGGP/HepGP synthase family. Group I subfamily.
Protein: KATG_SHEHH
Sequence: MANKKCPVMHGGATEISMSNMEWWPKALNLDILHQHDSKTNPMGAGFNYREQVKLLDVEALKKDLHALMTDSQPWWPADWGHYGGLMIRLSWHAAGTYRTADGRGGAGRGNQRFAPLNSWPDNVNLDKARRLLWPLKKKYGNKLSWADLIAYAGTIAYESMGLKTFGFAFGREDIWHPEKDIYWGAEKEWLAPSGSEGSRYSGERDLENPLASVMMGLIYVNPEGVDGHPDPLKTANDVRVTFERMAMNDEETVALTAGGHTVGKCHGNGDAELLGPVPEGADVEDQGLGWINKSQRGIGRDTVSSGLEGAWTTHPTQWDNGYFTLLLNHEWQLNKSPAGAWQWEPINIKEEDKPVDVEDLTQRYNPIMTDADMAMKLDPDYQIISARFDKDPEYFSDVFARTWFKLTHRDMGPKTRYIGPDVPAVDLLWQDPVPKGRSDYDVEAVKAQIAASSLSVSDMVTTAWDSARTFRGSDLRGGANGARIRLAPQRDWQANEPERLNRVLAVLEPIAAKSGVSVADVIVLAGNLAVEQAAKAAGFAIKVPFSPGRGDATADMTDVESFHVLEPLHDGYRNWLKKDYAVSAEELMLDQTQLLGLTAQEMTVLLGGMRVLGTNYNGESHGAFTEHQGALTNDFFVNLTDMNNTWQPVSNNLYEISDRETAKLKWTATRVDLVFGSNSILRAYAEVYAQDDNQQKFVEDFVTTWAKVMNSDRFDLD
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: PEX3_DEBHA
Sequence: MPIFSSLNSFLRRHKKKLIVTATLTFSAYFLVNQFIIKKLKNFQNSLRQELFVKEQIKRRFVQTQNDCYLTILALLPVLTQPIINHLPIELITQALKLKKTNSNPTPQEISDSLLTTDNLTMHQNTNDSSDLSHYMSLSKTELWKLLKIKTLTRTLTLMYSISGLLLLTRLQLNILARRSYLESAIILAGGKVNDTETSQDYFIEQSYLSLSWWLLNKGWLKISDLVEKVVTEKFNTINARTELSINKFDDLLCEMVNELSTNHNQEILNAVFPISYDNLIESLLNTNPELIKELDIEDSIMLKLINETTYLVSNEAFGDILINMVDSCKSTLIENLLLSLDPENAYTNQEKVIDISNIKQFKLANLLAQLSIQCGVLCDNNNLMNDTFSNELSGNIYMNNLNEIESLDEFSASIYSNFE
What is the function of this protein?
Involved in peroxisome biosynthesis.
What are the official names of this protein?
Peroxisomal biogenesis factor 3, Peroxin-3.
What is the protein family that this protein belongs to?
Belongs to the peroxin-3 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Single-pass membrane protein.
Protein: ACSA_ALCBS
Sequence: MSQVHIHPVPADYKKQTLMDRETYDRWYSQSINDPGTFWAERAEQLLDWKTPWDTVSEWDFNEGRAAWFKGATLNACYNCVDRHLPERANQTAIIWEGDEPDQDKHISYQQLFEEVSKFGNVLKNRGVKKGDRVVIYMPMIPEAAYAMLACARIGAIHSVVFGGFSPEALKDRILNAEACALITADEGVRGGKTIPLKVNADKALDGIDCVHTCLTVKRTGGDVDWQAPRDVWYHEAMADASSDCEPEWVEAEDPLFTLYTSGSTGKPKGVVHTTAGYLLNTALTHKYVFDYQDGDIYWCTADVGWITGHSYIVYGPLANGATTLMFEGVPTYPDASRCWQVVDKHKVNIFYTAPTAIRALMGLGDAPVEQTSRASLKLLGTVGEPINPEAWEWYYRVVGDSRCPIVDTWWQTETGAIMIAPLPGAVDLKAGSATLPMFGVQPGLMDPDGNELDGAASGNLVLKASWPSQIRTVYGDHQRLIDTYFSAYKGCYFTGDGARRDEDGYYWITGRVDDVLNVSGHRLGTAEIESALVLHPSISEAAVVGYQHDVKGQGIYAYVSLMAGKEGSEELVKALRDLVTQEIGPIAKPDLIHFAPGLPKTRSGKIMRRILRKIAADELDSLGDTSTLADPSVVDQLIDNRQNK
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: TUEI_GEMSP
Sequence: CEDGGVPSASCRANTEDYRYCNACYLQEVIGK
What are the official names of this protein?
Turripeptide XIV-18, Turripeptide IX-18.
What are the subcellular locations of this protein?
Secreted.
Protein: PTLI_STRAW
Sequence: MSQHTFVAGTAPGAVPVVGHAWQMMRRPLHFMSSLSAHGDLVKIRIGPTSAYVPCHPELLRQVLTNDRVFDKGGVFYDRARDIAGNGLVTCPYRDHRRQRRLMQSAFQRTQLERYSTAMRAEIDATAARWHDGTVIDAFPELYGMALRTVARTLYSTPVTEELAQRVEQAFDTVLNGLFRQMFLPHSLRRLPTPANLRYRNNLRFLHDTVQDLITEYRRDDTQRDDLLSALLASRDEDGGRLGDTEIHDQVITVMAAGTETVAGTLTWIFHLLSRHPEIEARLYEEIDTVLDGKPPHWDDLPSLSLTDRIITEALRMYPPAWIFTRLTASDVDLAGVRLPEGTTIVFSPSSVQRHSEAYDDASRFDPDRWLPDRTSAVARQAFTAFGTGARKCIGDLFARTEATLALATMLSQWRVTVEPDADVRPVALATVYHPRRLRLRLTARTPGQ
What is the function of this protein?
Catalyzes the conversion of pentalenene to pentalen-13-al by stepwise oxidation via pentalen-13-ol, a precursor of neopentalenolactone antibiotic.
What are the official names of this protein?
Pentalenene oxygenase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: NRDI_BRUA1
Sequence: MSLIVYFSSRSGNTHRFVERLGVRSSRIPLEASGALQVREPFVLVTPTYGGGSTKGAVPNPVIRFLNDADNRALIRGVIAAGNSNFGEAFCIAGNIISAKCGVPYLYRFELLGTAEDVGNVRNGMEQFWTRQTQA
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: PDXS_FRATN
Sequence: MSDINIKIGLAEMLKGGVIMDVVNAEQAEIAQQAGAVAVMALERVPADIRKDGGIARMSDPKLIKEIMSVVSIPVMAKARIGHFVEAQILESLGVDFIDESEVLTPADELNHIDKDSFKVPFVCGCTNLGEALRRIGEGAALIRTKGEAGTGNIVEAVRQLRQVNKDINYIKNADKSELMAIAKNLQAPYDLVTYVHKNGKLPVPNFSAGGVATPADAALMMQLGAESVFVGSGIFKSADPLKRARAIVSAVTYYNDAKILAEVSEDLGEPMTGINCDFEKFSQRGW
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: UCK1_DANRE
Sequence: MNSSGLLCDNERPRHRPFLIGVSGGTASGKSTVCAKIMELLGQNKVDHHQRKVTIVSQDSFYRVLTPEQKAKALKGQYNFDHPDAFDTEFMCQTLKDIVEGKVVEVPTYDFVTHSRLPEKICVYPADVVLFEGILVFYTQEVRDMFHMKQFVDTDSDVRLSRRVLRDMNRGRDLEQILTQYTTFVKPAFEEFCLPTKKYADVIIPRGVDNMVAINLIVQHIQDILNGDICKWQRGSVNGHNHGRSLKRGVAEHGENPSGSSSNLTKRPLLEPSTRPH
What is the function of this protein?
Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate.  Does not phosphorylate deoxyribonucleosides or purine ribonucleosides.  Can use ATP or GTP as a phosphate donor.
What are the official names of this protein?
Uridine-cytidine kinase 1, UCK 1, Cytidine monophosphokinase 1, Uridine monophosphokinase 1.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
Protein: BTBD8_MOUSE
Sequence: MAHCGAGGAAPVALLSSPGHGRKGLPRKGPGERRRLKAAVSEQLSRDVLRLLREEIHTDTILSVSGSLFKVHKAVLLARAPGFHSHIIEHTSSDLTNELVPVDGVEASEFKAFLQIVYSSNKNIKNYEEEIVKKLKVGSLMPEKGPDVSFPRYRTSSDCFLGKGEIPEDITGGGDCFISKADSDLEPASELGGDLLKLYLSQHYPDIDICVDGRSFRAHRAILSARSSYFAAMLSGCWAESSQECITLQGITHVEMNVMMHFIYGGTLDFPEKANVGQILNVADMYGLEGLREVAIYVLRRDYCNFFQKPVPRTWASILECLIIAHSVGVESLFADCMNCIISHFARFWSERSFANVPPEIQKTCLSMQIQSLNHGNAAFLLMESDRLIMGLPRVKWTEAALSMASQLQEECVTFIVENFSQIIESENFTLLLQSQAMSSTAHLLDKIFKAIEDNITAENSCSLLMALDTLLNSESTKEMGFTCRIQAVRGKLWAFLVQSFYAVRHTGSWKLMHLDDQQKIQVAALDKGDDRRLGRKPVLTSSQQRRQGSDVDVLKIKPWTENNKKPCQTSLSTNQKMRSDGLGASGHASSTNRNSINKVSKHGDSTKMSKVVKEMKTGGKYVSGKSKTMVKPQTENSDHTKIEGLSSTVVGRPSRVTAAGRKDPVHGKGVQNQEVETTGARPKVLTANLNVQARAKPLQTLRGKDSTCPASVGPSSRSTHSSTELLASMGSVDETKENGSVEDKCRDGKPYVSDSPGQMVSNGVMSTAAVKSRAVARITNGTASNKSFTHEQDSHGNSSVIKRGDGKGLSASAPQTAAKKRGSSNGCTAAQPRTKSAPPTLAQAQGSQGESPHSVKSSVSSRQSDENVTRLRHGTDKQIPKRKVVKQGHTTLQKVNAKLVPMPKIPSQPKKGGTVNSKDSKQKVLPGQIMLQSHASQRPSKPEVAEKSVLHGVSDSRNHVSKQRPHESPCTLACDTSGPEVSQIPCRPQPQSPLGSQEKKRLELACQDRSTLGDSVKRELRSELAGIEQSHTSAYKDSSQCNGNPNCGSIAALKSVISNPNENLINSNPVHNSDSANTEQAYLSDRERETGRENTDTEPSMSCINGKAFLCVPEGTSSTLNPTQSDRRLTFHGAAQSQLPDDCATEDSKCATVTSAVSSKCLLGQPSEKNCKNMEMSETPESHGTPEAPFVGPWDLNTGATHQRESPESDTGSATTSSDDIKPRSEDYDAGGSQDDEGSHDRGISKCSTALCHDFLGRSSSDTSTPEELKVHEGDLRTEVRVRKQGGGDHQIHSASDDEIPRKKPEPWSRSTIGYPREKGSTPRGSIPSAQEGDQVSSSADETEDERSEAENVGENSSPCSSGTQQVQGIINLAFDDGAEHESREFSATKKFRRSVLLSVDECEEVGSDEGEGHTPFQPSLDSLSPSDVFDGVSYEHHGRTGYSRFFKENEATTAEHNHNKGNGGYKNESFLLNSRSKDFEKQDKQCVSTDQKTRLDVPPKGSQQLFPENEEVISKREAAHSFQQHSTFMDGDTKSQERPCHLELHQRELSSNIPKISSVKSLDSCPSQGLPQEGQVKESRPTPPKGANNAVFSGDIDDCDTMAQTSMYDHRPSKTLSPIYEMSLTAACEQEVESETHVADRGSEDEQHFAKQDWTLLRQLLSEQDANLNITSSLPEDLSLAQYLINQTLLLARDSSKPQGSAHADTWNRWSELSSPLDDSATSATTASVSSTDCSPQGEWTILELETQH
What is the function of this protein?
Involved in clathrin-mediated endocytosis at the synapse.  Plays a role in neuronal development and in synaptic vesicle recycling in mature neurons, a process required for normal synaptic transmission.
What are the official names of this protein?
BTB/POZ domain-containing protein 8, AP2-interacting clathrin-endocytosis protein, APache.
What are the subcellular locations of this protein?
Nucleus. Note=Localized to nucleus in fetal cells.
Protein: KTHY_CHLPD
Sequence: MLITFEGIDGAGKSTQIKKLQTVLNKAGVESVTLREPGGTEVAEKIRSILLESRHEISAVGELLLFSATRAELVQQVIIPALQTDAVVILDRFYDSTRAYQGYGRGIDLTILETIIAFSTFNLIPDVTFYLDIKPEDAMIRKNSKKSLPLAFENSDLDRMERSGLEFYSKVRNGYFEIIRSEQHRFKVLNALEHPDDLHRQILETLRKKKPALKALNRY
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: UBIG_SALPK
Sequence: MNTEKPSVAHNVDHNEIAKFEAVASRWWDLEGEFKPLHRINPLRLGYITERSGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLRALESGIEVEYVQETVEEHAAKHAQQYDVVTCMEMLEHVPDPQSVVHACAQLVKPDGEVFFSTLNRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLSWVDETVLKEQHITGLHYNPITNTFKLGPGVDVNYMLHTRAKKA
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.