PharMolix/UniProtQA huggingface dataset:
Protein: HBB_CHLAE
Sequence: VHLTPEEKTAVTTLWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFAQLSELHCDKLHVDPENFKLLGNVLVCVLAHHFGKEFTPQVQAAYQKVVAGVANALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: CBHA_ASPCL
Sequence: MYQRALLFSALATAVSAQQVGTQKAEVHPALTWQKCTAAGSCTDQKGSVVIDANWRWLHSTEDTTNCYTGNEWNAELCPDNEACAKNCALDGADYSGTYGVTADGSSLKLNFVTSANVGSRLYLMEDDETYQMFNLLNNEFTFDVDVSNLPCGLNGALYFVSMDADGGLSKYPGNKAGAKYGTGYCDSQCPRDLKFINGEANVEGWKPSDNDKNAGVGGYGSCCPEMDIWEANSISTAYTPHPCDGMEQTRCDGNDCGGTYSSTRYAGTCDPDGCDFNSFRMGNESFYGPGGLVDTKSPITVVTQFVTAGGTDSGALKEIRRVYVQGGKVIGNSASNVAGVEGDSITSDFCTAQKKAFGDEDIFSKHGGLEGMGKALNKMALIVSIWDDHASSMMWLDSTYPVDADASTPGVARGTCEHGLGDPETVESQHPDASVTFSNIKFGPIGSTYKSV
What is the function of this protein?
The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose.
What are the official names of this protein?
Probable 1,4-beta-D-glucan cellobiohydrolase A, Beta-glucancellobiohydrolase A, Cellobiohydrolase D, Exocellobiohydrolase A, Exoglucanase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 7 (cellulase C) family.
What are the subcellular locations of this protein?
Secreted.
Protein: VP5_IBDV5
Sequence: MVSRDQTNDRSDDKPARSNPTDCSVHTEPSDANNRTGVHSGRHPGEAHSQVRDLDLQFDCGGHRVRANCLFPWIPWLNCGCSLHTAEQWELQVRSDAPDCPEPTGQLQLLQTSESESHSEVKHTPWWRLCTKRHHKRRDLPRKPE
What is the function of this protein?
Plays a role in the release of virion progenies by disrupting the host plasma membrane.
What are the official names of this protein?
Protein VP5.
What is the protein family that this protein belongs to?
Belongs to the avibirnavirus/aquabirnavirus VP5 protein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: DNAK_MYCA1
Sequence: MARAVGIDLGTTNSVVAVLEGGDPVVVANSEGSRTTPSIVAFARNGEVLVGQPAKNQAVTNVDRTIRSVKRHMGTDWSIEIDGKKYTAQEISARVLMKLKRDAEAYLGEDITDAVITVPAYFNDAQRQATKEAGQIAGLNVLRIVNEPTAAALAYGLDKGEKEQTILVFDLGGGTFDVSLLEIGEGVVEVRATSGDNHLGGDDWDDRIVNWLVDKFKGTSGIDLTKDKMAMQRLREAAEKAKIELSSSQSTSINLPYITVDADKNPLFLDEQLTRAEFQRITQDLLDRTRQPFKSVIADAGISVSDIDHVVLVGGSTRMPAVTDLVKELTGGKEPNKGVNPDEVVAVGAALQAGVLKGEVKDVLLLDVTPLSLGIETKGGVMTKLIERNTTIPTKRSETFTTADDNQPSVQIQVYQGEREIAAHNKLLGSFELTGIPPAPRGVPQIEVTFDIDANGIVHVTAKDKGTGKENTIKIQEGSGLSKEEIDRMIKDAEAHAEEDRKRREEADVRNQAESLVYQTEKFVKDQREAEGGSKVPEETLSKVDAAIADAKTALGGTDITAIKSAMEKLGQESQALGQAIYEATQAESAQAGGPDGAAAGGGSGSADDVVDAEVVDDDRESK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: GLSA_ACAM1
Sequence: MSELQVLLESFHQTYHQQDAGQLACYIPELCKADPNWFAISIVTTDGQTFQVGNCQQTFTIQSISKVFVYGMALADHGQDALLAKVGVEPTGDPFNSLIRLDEDSKRPDNPMINAGAIATTSLIRGNGPTDRLNRLLEMFRRYVGHEVFIDMPVFMSERDTGHRNRAIAHLMLNFGMIDKNIDEALDLYFQQCSVLVNCHDLAVMAATLAHKGINPITQERAVESGYVKDILSVMYTCGMYDFAGEWAYKVGLPAKSGVSGGIMAVVPNRAGIAVFSPLLDEYGNSIRGRRVLEALSQKLGLHLFDLSMGGCGLQAAMDSN
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: SYNRG_RAT
Sequence: MALRPGAGASGAAGAGTGPGGAGSFMFPVAGGMRPPQGLIPMQQQGFPMVSVMQPNMQGMMGMNYSSQMSQGPIAMQAGIPMGPMPAAGVPFLGQPPFLGMRPAAPQYTPDMQKQFAEEQQKRFEQQQKLLEEERKRRQFEEQKQKLRLLSSVKPKTGEKNRDDALEAIKGNLDGFSRDAKMHPTPASHPKKPDCPTSSHSTKTVSPSSAFLGEDEFSGFMQGPVELPTCGPSSTAQPFQSFLPSTPLGQLHTQKAGAQPLPPGQAPVSFAVHGVHGQIPCLSAASASHSMQKAGPSLEEKLLVSCDISASGQEHIKLSSPEAGHRAVVPGSSKNSPGLMAHNGGAVDGCVSGPTTAVAEKTSDQNLSKEESGVGVFPSQDPVQPRMPPWIYNESLVPDAYKKILETTMTPTGIDTAKLYPILMSSGLPRETLGQIWALANRTTPGKLTKEELYTVLAMVAVTQRGVPAMSPDTLNQFPAAPIPTLSGFPMTLPTPVSQPTAMTSGPAGSIPLSLGQPIMGINLVGPVGGAAAPTSSGFMPAYPSNQVGKTEEDDFQDFQDASKSGSIDDSFTDFQEVPASSKTSNSQHGNSAPSLLIPLPGTKASTDKYAVFKGISAEKPSENPASFGESGDKYSAFRELEPTADSKPLGESFAEFRSTGTDDGFTDFKTADSVSPLEPPTKDSFPSAFASGAAQQTQTQVKTPLNLADLDMFSSVDCSGEKPVPFSAAFSTSKSVSSRPQPAGSAAAPASLASTKASSLADDFGEFNLFGEYSNPASVGEQDDFADFMAFGNSSIPSEPKADDKYEALREEGSPGALSTSTVEGAHNPPVSSSKYDVFKQLSLEGAGLAIEEFKENTPSTKSDGDFADFHSSKFSSTSSDKSLGEKAVAFRHAKEDSASVKSLDLPSIGGSSVGKEDSEDALSVQFDMKLADVGGDLKHVMSDSSLDLPTVSGQHPPAAGSALASEDALPETPFPAFASFKDMMPQTTEQKEYESGDFQDFTRQDMPMVDRSQENTCPSPASSVASHETPKEGADDFGEFQSEKPKISKFDFLVANSQSKMKSSEEMIKSELATFDLSVQGSHKRSLSLGDKEISRSSPSPALEQPFRDRSNTLSERAALPVIRDKYKDLTGEVEENERYAYEWQRCLGSALDVIKKANDTLNGISSSAVCTEVIQSAQGMEYLLGVVEVYRVTKRVELGIKATAVCSEKLQQLLKDIDKVWNNLIGFMSLTTLTPDENSLDFSSCMLRPGIKNAQELACGVCLLNVDSRSRKEETPAEEQPKKAFNSETDSFKLAYGGHQYHASCANFWINCVEPKPPGLLLPDLL
What is the function of this protein?
Plays a role in endocytosis and/or membrane trafficking at the trans-Golgi network (TGN) (By similarity).  May act by linking the adapter protein complex AP-1 to other proteins (By similarity).  Component of clathrin-coated vesicles (By similarity).  Component of the aftiphilin/p200/gamma-synergin complex, which plays roles in AP1G1/AP-1-mediated protein trafficking including the trafficking of transferrin from early to recycling endosomes, and the membrane trafficking of furin and the lysosomal enzyme cathepsin D between the trans-Golgi network (TGN) and endosomes (By similarity).
What are the official names of this protein?
Synergin gamma, AP1 subunit gamma-binding protein 1, Gamma-synergin.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Cytoplasm, perinuclear region. Cytoplasmic vesicle, clathrin-coated vesicle. Note=Localization at clathrin-coated vesicles depends on AFTPH/aftiphilin (By similarity). Associates with membranes via the adapter protein complex AP-1 (PubMed:10477754). Colocalizes with AP1G1 (PubMed:10477754).
Protein: DPO3A_CAUVC
Sequence: MSDAEGQGFVHLRVRSAYSLLEGAIKADQIGKLAAEAKMPAAGLADRANLFGALEYSSYAKDAGVQPIIGCAIPVVGIGGGPTERWARAPTLMLLAQNERGYLNLSELSSIAYLDSAELPEPVVPWAKVAEHSEGLILLSGGTDGPVDALFAAGKTAEASAALAEMHRVFGDRFYVELQRHGLPRQAAAEPGLVNWAYDHDVPLVATNDVYFAKPGFYDAHDALLCISDGAFVGQDERRRVTPEHWFKPAEEMRKLFADLPEACDNTLDIARRCAFMVHKRDPILPSFPTGDGRNEAEELEHQAREGLKMRLEGLTLSAPEEEYWKRLDFELGIIKKMGFPGYFLIVSDFIKWGKAHGIPVGPGRGSGAGSLVAWVLTITDLDPLRFGLLFERFLNPERVSMPDFDVDFCQERREEVISYVQEKYGRDRVAQIITFGSLQARAVLRDVGRVMQLPLGLVDRLCKMVPNNPAAPVTLAQAIDLEPRLKQAKKEDANVSACLDVALQLEGLFRNASTHAAGLVIGDRPLTQLTPLYKDPRSDLPATQFNMKWVESAGLVKFDFLGLKTLTVLDRAVKHLKKRGFEIDLGKLPFDDAKTYELLASGQTVGVFQLESQGMRDTLRKMRCGSIEEITALISLYRPGPMDNIDTFVDCKFGRKPVDTLHPSLEAVLKETYGVIVYQEQVMQIAQILAGYSLGEADLLRRAMGKKKKEEMDLQKIRFVSGAKEKNVPEEQSGSIFELVAKFAGYGFNKSHAAAYAFISYQTAWLKANTPVEFFAASMSLDLSNTDKLAVFHQDARRFGITVRAPDVNRSGADFEVENGEVLYALGAIRNVGLEAMKHLVAVRAEGGPFRDVFDFVERIDPRQVNKRAIENLARAGAFDSIHKNRAQIVASADVLIAHAQSCHADRQGGQGGLFGSDPGAGRPRLSKTENWNQVDLLDEELSAVGFYLTGHPLEDMVGMLRRRRTVMLAEAMAQAEAGAEAFRMCGVVRRRQERASQSGEKFAFVSLSDPTGEYEVLYPPESLRKCRDVLEPGKAVAIKVRAKARDGEVRFFGDDAEPIEKAVENVVAGLRVHLSPSAAEIDALKRRLEPAQAQKGGEVTFVAAIGGGREIELRLPGRYTLDAALRGALKTAPGVALLEDV
What is the function of this protein?
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.  The alpha chain is the DNA polymerase (By similarity).
What are the official names of this protein?
DNA polymerase III subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. DnaE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_BACC2
Sequence: MNKGRVTQIMGPVVDVKFDGGKLPEIYNALTVKQSNENGSMNLTFEVALHLGDDTVRTVAMSSTDGLVRGTEVEDTGKAISVPVGDVTLGRVFNVLGDAIDLDGELPADVHRDPIHRQAPAFEELSTKVEILETGIKVVDLLAPYIKGGKIGLFGGAGVGKTVLIQELINNIAQEHGGISVFAGVGERTREGNDLYHEMSDSGVIKKTAMVFGQMNEPPGARQRVALTGLTMAEHFRDEQGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTNKGSITSIQAVYVPADDYTDPAPATTFAHLDATTNLERRLTQMGIYPAVDPLASTSRALSPEIVGEEHYEVARQVQQTLQRYKELQDIIAILGMDELSEEDKLVVHRARRIQFFLSQNFHVAEQFTGQKGSYVPVKNTVSGFKEILEGKYDDLPEDAFRLVGGIEEVIENAKKMMA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MSRA_DROME
Sequence: MSLTITSSVTHPELKDLSTVRNEQKELNISPVHDVNVTKATATFGMGCFWGAESLYGATRGVLRTTVGYAGGSSDLPTYRKMGDHTEVLEIDYDPTVISFKELLDLFWNNHEYGLTTPIKRQYASLILYHDEEQKQVAHASKLEEQERRAPEIITTEIASKENFYPAEAYHQKYRLQGHKDLASSLNLSPKLLQTSYVATKLNGYLAGVGGIEQFKAEAETMGLTPTQRQYCYYHVEQNEGQGLYC
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reduction of methionine sulfoxide in proteins to methionine (PubMed:12145281, PubMed:30529269).  Does not catalyze the reverse reaction involving the oxidation of methionine residues (PubMed:30529269).
What are the official names of this protein?
Peptide methionine sulfoxide reductase, Ecdysone-induced protein 28/29 kDa, Methionine-S-sulfoxide reductase, Peptide-methionine (S)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: RPOZ_RUEPO
Sequence: MARVTVEDCVDKVPNRFELVLLAAHRAREISAGAAITVDRDNDKNPVVSLREIADETQSADDLRERLIEANQTQIEVDEPEEDQMALLMGAESDRPVEDDMSEERLLRALMEAQGQG
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: IF2G_SACS2
Sequence: MAWPKVQPEVNIGVVGHVDHGKTTLVQAITGIWTSKHSEELKRGMTIKLGYAETNIGVCESCKKPEAYVTEPSCKSCGSDDEPKFLRRISFIDAPGHEVLMATMLSGAALMDGAILVVAANEPFPQPQTREHFVALGIIGVKNLIIVQNKVDVVSKEEALSQYRQIKQFTKGTWAENVPIIPVSALHKINIDSLIEGIEEYIKTPYRDLSQKPVMLVIRSFDVNKPGTQFNELKGGVIGGSIIQGLFKVDQEIKVLPGLRVEKQGKVSYEPIFTKISSIRFGDEEFKEAKPGGLVAIGTYLDPSLTKADNLLGSIITLADAEVPVLWNIRIKYNLLERVVGAKEMLKVDPIRAKETLMLSVGSSTTLGIVTSVKKDEIEVELRRPVAVWSNNIRTVISRQIAGRWRMIGWGLVEI
What is the function of this protein?
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
What are the official names of this protein?
Translation initiation factor 2 subunit gamma, aIF2-gamma, eIF-2-gamma.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
Protein: LUC8_FUSSX
Sequence: MMHAFHHLAVLLIGSLPASASTLPHPDGYRHVNGSCSKSVAVPAVWNGFGYLFNITVGTPPQELTMLSDWTWMSLFVRSGRCLNQYDPSLCLGTSGQTWFDERASTSFANTSLPQLSWPLTAFAPNFTVDYGTDDVCIGDLCSAGTVLQVSDFPYPGEGIPKVPFSGIFGMAPVTAGLNETFHPANYQAWKAGRLGSRVGWNSCAALASSDPCLGGEAKLVFGGTDSSLYDDDTLRIYEIQNPDWLSDAFYPLTPPRENYWTTPLTGSWILGTSEEESRNFAVPFSGSNGSNVTPLAVLDEGSEGLGAPLSLNAYNWLVDQVRGTLASNDTIEEIHAQGSSGFNTAEQNWYTVSCDDIDSYPELVYELNGHTNYTVPPQDYVTKLSDSSTCYLNINLWKYGRTEDGNAKVALLGLAFLKRLYVVLDFETQSFGLAPLSM
What is the function of this protein?
Secreted aspartic protease; part of the gene cluster that mediates the biosynthesis of the mycotoxin lucilactaene and the lucilactaene-related compound NG-391 that act as cell cycle inhibitors with potent growth inhibitory activity against malarial parasites, moderate growth inhibitory activity against cancer cells, and no activity against bacteria and fungi (PubMed:32043422, PubMed:35484225).  Within the cluster, LUC7 and LUC8 encode proteins which are not commonly involved in the biosynthesis of secondary metabolites and are not essential for lucilactaene biosynthesis (Probable).
What are the official names of this protein?
Secreted aspartic protease LUC8, Lucilactaene biosynthesis cluster protein 8.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: BCAT_NEMVE
Sequence: MAARVGLLQTIGKLQSSFLYRAWPKHSINAKQLARQLSSYHDIKSSNLLIEKTNKPKPKPDPNTLVFGKEFTDHALILKWSDEDGWDNPQIIPYGNLSLPPAASALHYGLECFEGMKAYRGDDGKIRMFRPLMNMKRMNNSAARACLPTFNSGEMVECIRKLIHLEREWVPHSNTCSLYIRPTMIGTQASLGVNKANSAMLFVILSPVGPYFRTGTFNPVALLADPQYVRAWPGGVGDCKMGGNYAPTILAQQNAERQGLQQVLWLFGEDHQITEVGTMNMFMFWINENGEKELVTPPLNGLILPGVTRDSLLALAKRWGEFKVTERTFNMQDVLMATEENRMLEMFGSGTACVVCPINRIFYQGKNIMIPTMENLNVTKRVYDELTGIQYGRQEGPKDWIVMVD
What is the function of this protein?
Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine.
What are the official names of this protein?
Branched-chain-amino-acid aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
Protein: INS_ATRSP
Sequence: AANQHLCGSHLVEALYLVCGEKGFFYNPNKVGIVEQCCHKPCTIYELENYCN
What is the function of this protein?
Insulin decreases blood glucose concentration.  It increases cell permeability to monosaccharides, amino acids and fatty acids.  It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
What are the official names of this protein?
Insulin.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TSAD_SHIF8
Sequence: MRVLGIETSCDETGIAIYDDEKGLLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQAALKESGLTAKDIDAVAYTAGPGLVGALLVGATVGRSLAFAWNVPAIPVHHMEGHLLAPMLEDNPPEFPFVALLVSGGHTQLISVTGIGQYELLGESIDDAAGEAFDKTAKLLGLDYPGGPLLSKMAAQGTAGRFVFPRPMTDRPGLDFSFSGLKTFAANTIRDNGTDDQTRADIARAFEDAVVDTLMIKCKRALDQTGFKRLVMAGGVSANRTLRAKLAEMMKKRRGEVFYARPEFCTDNGAMIAYAGMVRFKAGATADLGVSVRPRWPLAELPAA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRXB_SCHPO
Sequence: MTHNKVVIIGSGPAGHTAAIYLARGELKPVMYEGMLANGIAAGGQLTTTTDVENFPGFPDGINGTTLTENFRAQSLRFGTEIITETVSKLDLSSRPFKYWLEGAEEEEPHTADSVILATGASARRLHITGEDTYWQAGISACAVCDGAVPIYRNKPLAVVGGGDSAAEEAQFLTKYGSKVYVLVRRDKLRASPIMAKRLLANPKVEVLWNTVAEEAQGDGKLLNNLRIKNTNTNEVSDLQVNGLFYAIGHIPATKLVAEQIELDEAGYIKTINGTPRTSIPGFFAAGDVQDKVFRQAITSAGSGCQAALLAMHYLEELEDTD
What are the official names of this protein?
Thioredoxin reductase, Caffeine resistance protein 4.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX821_LYCSI
Sequence: MKLMIFTGLVLFAIVSLIEAQAENEKPCLPEYKVRTHAPGNCCSDLVCDCYGRYKSGAQIGRNCFCLQKGVIYKREN
What are the official names of this protein?
U8-lycotoxin-Ls1l, Toxin-like structure LSTX-H21.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 08 (U8-Lctx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NRDI_BACSU
Sequence: MVQIIFDSKTGNVQRFVNKTGFQQIRKVDEMDHVDTPFVLVTYTTNFGQVPASTQSFLEKYAHLLLGVAASGNKVWGDNFAKSADTISRQYQVPILHKFELSGTSKDVELFTQEVERVVTKSSAKMDPVK
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: PIR3_YEAS7
Sequence: MQYKKPLVVSALAATSLAAYAPKDPWSTLTPSATYKGGITDYSSSFGIAIEAVATSASSVASSKAKRAASQIGDGQVQAATTTAAVSKKSTAAAVSQITDGQVQAAKSTAAAASQISDGQVQAAKSTAAAVSQITDGQVQAAKSTAAAVSQITDGQVQAAKSTAAAVSQITDGQVQAAKSTAAAVSQITDGQVQAAKSTAAAASQISDGQVQAAKSTAAAASQISDGQVQAAKSTAAAASQISDGQVQAAKSTAAAASQISDGQVQATTSTKAAASQITDGQIQASKTTSGASQVSDGQVQATAEVKDANDPVDVVSCNNNSTLSMSLSKGILTDRKGRIGSIVANRQFQFDGPPPQAGAIYAAGWSITPEGNLALGDQDTFYQCLSGDFYNLYDKHIGSQCHEVYLQAIDLIDC
What is the function of this protein?
Component of the outer cell wall layer.  Required for stability of the cell wall and for optimal growth.  Required for resistance against several antifungal and cell wall-perturbing agents (By similarity).
What are the official names of this protein?
Cell wall mannoprotein PIR3, Covalently-linked cell wall protein 8, Protein with internal repeats 3.
What is the protein family that this protein belongs to?
Belongs to the PIR protein family.
What are the subcellular locations of this protein?
Secreted, cell wall. Note=Covalently attached to the cell wall.
Protein: DYL1_YEAST
Sequence: MSDENKSTPIVKASDITDKLKEDILTISKDALDKYQLERDIAGTVKKQLDVKYGNTWHVIVGKNFGSYVTHEKGHFVYFYIGPLAFLVFKTA
What is the function of this protein?
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function.  Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.  May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity).  Also a component of the nuclear pore complex where it may contribute to the stable association of the Nup82 subcomplex with the NPC (PubMed:17546040, PubMed:23223634, PubMed:25646085).
What are the official names of this protein?
Dynein light chain 1, cytoplasmic.
What is the protein family that this protein belongs to?
Belongs to the dynein light chain family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Nucleus, nuclear pore complex.
Protein: NIFW_AZOVI
Sequence: MTVQPFSPDSDLTLDEAMDELVSAEDFLEFFGVPFDQDVVHVNRLHIMQRYHDYLSKAGDLDEHDDQARYAVFQKLLARAYLDFVESDALTEKVFKVFRMHEPQKTFVSIDQLLS
What is the function of this protein?
May protect the nitrogenase Fe-Mo protein from oxidative damage.
What are the official names of this protein?
Nitrogenase-stabilizing/protective protein NifW.
What is the protein family that this protein belongs to?
Belongs to the NifW family.
Protein: NRDR_PAEAT
Sequence: MYCPFCRNPDSRVVDSRMADDGSSIRRRRQCPECGRRFTTVETTSLSVIKRSGVGEPFSRIKVISGVRKACQGRPVTEDDLAMLAQEVEENIRSSGAAEIDAHEVGLAILGPLRKLDEVAYLRFASVYQAFESLEDFESAISLLRHEAEAAKAGAKKATGSEKSQL
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: AROB_BARQU
Sequence: MQTKTVTVKLDKHCYDIIIGPGLVAQAVWQIKHSLHKKDLHQTRFALVTDSNVASLHLDTLQAELTKNKIHTVPIIVEAGEQSKSFLTLQIVIDRILAARLERGDCVIAFGGGVIGDLGGFAASIIRRGMNFIQMPTTLLAQIDSSVGGKTGINSRYGKNLIGAFYQPQCVIADTCFLDTLPLREFRAGYAEIVKYGLISQPDFFEWLEKNWQKIFSNGPTRTEAIVRSCQFKADIVARDEHETGERALLNLGHTFGHMLETATAYDSNRLIHGEAVAIGMVLAHQFSAQLNLINPTLIQRVEAHLKAVGLPTQLKDIPGKLPEAETLMTLIAQDKKVSQNNLTFILTRGLGQSFIAKTVSPEAVLAFLEQKLAEIR
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_NITSB
Sequence: MVDIDYYELLEVDRNASFEEIKKAYRKLALKYHPDRNPDNPEAEEKFKLINEAYQVLSDEEKRALYDQYGKAGLENQGFSGFNQKSFDDIMDFFESVFGETFGGGFGSRRRSDEKYPLDLSIEMEISFQEALFGTQKEVHYSFKVPCSACKGTGAKDGKLTACPECHGRGQIYYRQGFMTFSQTCPRCHGQGEVAQEHCEECSGKGYRIEKEKITIDIPEGIDSGNRIRAQSRGNVSASGMRGDLYITVFVQEDDHFVRYNDDIYMEVPIFFTQAALGETITIPTPRGERELQLNVGTKDKEQFVFKGEGFKNVHTGKKGNLIAQVKIIYPTSLNDEQKELLHKLQESFGVESKPHEEKFSSIFEKVKNWFTK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_RHOPB
Sequence: MARVKRGVTAHAKHKKVYKLAKGFRGRRKNTIRTAKAAVDKAGQYAFRDRKRKKRTFRALWIQRINAAVRPLGMTYSVFINGLAKSGVMVDRKVLSDLAITEPAAFLAIAEKAKAALAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.