PharMolix/UniProtQA huggingface dataset:
Protein: PYRB_STRPJ
Sequence: MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHPIVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDVCVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVAIAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMMFLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVEAPKSRIVQQMTNGVFVRMAILESVLASRNAN
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: COTW_BACSU
Sequence: MSDNDKFKEELAKLPEVDPMTKMLVQNIFSKHGVTKDKMKKVSDEEKEMLLNLVKDLQAKSQALIENQKKKKEEAAAQEQKNTKPLSRREQLIEQIRQRRKNDNN
What are the official names of this protein?
Spore coat protein W.
Protein: MOAC_RHIME
Sequence: MSGPALTHIDSAGEASMVDVGDKAETVRVAVAEGFVRMKPETLALIRQGNAKKGDVIATARLAGIMAAKQTSSLIPLCHPLMLTKVSVDITPDDALPGLRVEAMAKLTGRTGVEMEALTAVSVACLTIYDMAKAADREMEIGGVRLVSKSGGRSGDYHRAGEMR
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: RL24_BACCR
Sequence: MHVKKGDKVQVITGKDKGKQGVILVAFPKQNRVIVEGVNIVKKHSKPSQLNPQGGIITKEAPIHVSNVMILDPKTGEPTRVGFKVEDGKKVRIAKKSGELLDK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: HISZ_CHRVO
Sequence: MRNWLLPEYIADILPATARQVESAKAAMLEGFRVAGYELVLPPLIEYIDSLVSEGDDTLDLKTFKLDDQLSGRQLGLRADITPQVARIDAHLLGERTGVTRLCYAGSVVHSRPSGLTSSREPLQVGAELYGYAGIEADQEIIELMLATLEKAGVKKLRLDVGHIAIYRGLAAAAGLSPEVSRELFGLLQNKDAAGIAARVAGVAEPYKSAFLALPELYGPAAVLEKARTRLPSLPEVELGLMQLSAIARAMEGRVELSFDLAELRGDFYHTGLMFAAYAPGWSDAIARGGRYDNVGRRFGRARPATGFSLDLRDLLRILPERDPSRGIRVSARHLPAAAAEVSRLRAEGEMVVVDYLGESAAALNCDRELVPAADGWQLAPFH
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YA64B_YEAST
Sequence: MAGEAVSEHTPDSQEVTVTSVVCCLDSVVEIGHHVVYSVVTPLIVAVLIDTMAGEAVLEHTSDSQEEIVTTVVCSVVPLVCFVVSVVCFVISVVEIGHHVVYSVVAPLTVTVAVETIAEEMDSVHT
What are the official names of this protein?
Uncharacterized membrane protein YAL064W-B.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MTGA_PSEPK
Sequence: MLSTLIRRLSRALLWFVAGSIVLVLVFRWVPPPGTALMVERKVQSWVNGEPIDLQRDWEPWENISDELKVAVIAGEDQKFASHWGFDLPAIQAALAHNERGGNIRGASTLTQQVAKNLFLWSGRSWFRKGLEAWFTALIELFWSKERILEVYLNSAEWGKGVFGAQAAARYHFGVDASRLSRQQAAQLAAVLPSPIKWSASRPSAYVASRAGWIRRQMSQLGGPSYLMQLDSSRKL
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: CARB_STRPJ
Sequence: MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEVVLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKEGPDALLPTLGGQTGLNMAMELSKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAATIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEYEVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALKIEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEVINPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEESLLKACRSLEIGVHHNEIPELAAVSDDTLIEKVVKAQDDRLFYVSEAIRRGYTPEEIAELTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQLRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIKSDKESVLVLGSGPIRIGQGVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDLEQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQPPGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDHPVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQETIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVATKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSDATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAAFFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEHGVPLFTALDTANAMLKVLESRSFVTEAI
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: RBMS2_MOUSE
Sequence: MLLSVTSRPGISTFGYNKNNKKLYVAQQMAPPSPRNSTPNSSGGGGGGSGGNDQLSKTNLYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSSAQKAVTALKASGVQAQMAKQQEQDPTNLYISNLPLSMDEQELEGMLKPFGQVISTRILRDTSGASRGVGFARMESTEKCEAIITHFNGKYIKTPPGVAAPSDPLLCKFADGGPKKRQSQGRYVQNGRAWPRNGDMGGMALTYDPTAALQNGFYAAPYSIAHSRMLAQSALAPYLPSPVSSYQGSVLTPGMDHPLSLQPASMMGPLTQQLGHLSLNSLGTFMPAAAAMHGAYISQYPAVPSSSVSAEESNGQQNQLAVEPPSDHGVYPFQFSK
What are the official names of this protein?
RNA-binding motif, single-stranded-interacting protein 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: DIAA_YERPE
Sequence: MLERIKGCFTESIQTQIAAAEALPDAISCAAMALVQSLLNGNKILCCGNGTSAANAQHFAASMINRFETERPSLPAIALNADNVVLTAITNDRLHDEVYAKQVRALGQAGDVLLAISTRGNSRDIVKAVEAAVTRDMTIVALTGYDGGELAGLLGQLDVEIRIPSHRGARVQELHMLTVNCLCDLIDNTLFPHQND
What is the function of this protein?
Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein.
What are the official names of this protein?
DnaA initiator-associating protein DiaA.
What is the protein family that this protein belongs to?
Belongs to the SIS family. DiaA subfamily.
Protein: GALT8_CAEEL
Sequence: MRRHVVLSIFVFAGIVFAAEEAEKLPKCEHVDPYENLEGWLDLKPLTERKCNHTLKENLTEAESKKSEWGIKSFAFDALSSEKLGPNRNVGKQAHKLCEEEKYDASYSTSVVVIHHNEALSTILRMINGIIEFTPKSLLKEIVLYEDASEEDHVLTKHLEKFAKIKGLEDKLIIKRSEYRQGLIRAKVHASRLATGEVIVFMDSHCEVAERWLEPLLQPIKEDPKSIVLPVVDLINPVSFDYSPSMVAKSGFDWGFTFKWIYLPWEYFETPENNVKPFNSPAMPGGLLAMRKEYFVELGEYDMGMEIWGSENIELSLKAWLCGGRVVVAPCSRVGHVFRMRRPYTSKPGMDTALYNAVRVAKTWLGEYESKFFAVKPRGAKMVFGDLTEPMQVKDRLKCKDMKWFIENVYPELEPKVHDEL
What is the function of this protein?
Potential glycopeptide transferase involved in O-linked oligosaccharide biosynthesis (By similarity).  In contrast to other members of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on peptides that have been tested.  Some peptide transferase activity is however not excluded, considering that its appropriate peptide substrate may remain unidentified.
What are the official names of this protein?
Probable N-acetylgalactosaminyltransferase 8, Protein-UDP acetylgalactosaminyltransferase 8, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 8, pp-GaNTase 8.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: GREB_VIBVU
Sequence: MKTKMITREGYNKLKQELDYLWKEHRPEITQKVSWAASLGDRSENADYTYNKRLLRQIDRRVRFLSKFLPEVKIVDYAPQQEGKVFFGAWVEIENEAGEVMKFRIVGPEEIYGDAKGYISIDSPMARALLKKEVDDEVQVPTPSGIKEWFINSIEYDKGE
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreB releases sequences of up to 9 nucleotides in length.
What are the official names of this protein?
Transcription elongation factor GreB, Transcript cleavage factor GreB.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family. GreB subfamily.
Protein: MDH_VIBVY
Sequence: MKVAVIGAAGGIGQALALLLKNRLPAGSDLALYDIAPVTPGVAADLSHIPTPVSIKGYAGEDPTPALEGADVVLISAGVARKPGMDRADLFNVNAGIVKSLAERIAVVCPNACIGIITNPVNTTVPIAAEVLKKAGVYDKRKLFGVTTLDVIRSETFVAELKGQDPGEVRVPVIGGHSGVTILPLLSQVEGVEFSDEEIAALTKRIQNAGTEVVEAKAGGGSATLSMGQAACRFGLALVKALQGEEVIEYAYVEGNGEHASFFAQPVKLGKEGVEEILPYGELSDFEKAALDGMLETLNGDIQIGVDFVK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: ATP7_KLULA
Sequence: MSLAKSAANKLDWAKVISSLKLTGKTATQLSSFKKRNDEARRQLLELQSQPTSVDFSHYRSVLKNTEVVDKIEQFYKSYKPVSVDVSKQLSTIEAFESQAIENAAETEKLVAQELKDLKETLNNIESARPFDQLTVDELTKARPEIDAKVEEMVKKGRWDVPGYKEKFGDLTIM
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements (By similarity).
What are the official names of this protein?
ATP synthase subunit d, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ATPase d subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein.
Protein: ESR2_BOVIN
Sequence: MDVKNSPSSLNSPVSYNCGQSILPLEPGPIYLPSSYVESRHEYSAVTFYSPAVMNYSIPNNSEDGPGRQTTSPNVLWPTPGHLSPLAIHCQPSVLYAEPQKSPWRETRSLEHTLPVNRETLKRKASGSSCASPATSPSSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRIVRRQRNSDEQLHCLSKTKRNGGPMTRVKELLLSALSPEQLVLTLLEAEPPHVLISRPSTPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLYDQVRLLESCWLEVLMVGLMWRSIDHPGKLIFAPDLILDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPSATAPQEADSGRKLTHLLNAVTDALVWVIAKSGMSSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAHTLRGNKSLVTGSERNLVEDSESKEGSQKPQAQ
What is the function of this protein?
Nuclear hormone receptor.  Binds estrogens with an affinity similar to that of ESR1ESR1/ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner.
What are the official names of this protein?
Estrogen receptor beta, ER-beta, Nuclear receptor subfamily 3 group A member 2.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNPC3_PONAB
Sequence: MAAPEQPLAISRGCTSSSSLSPPRGDRTLLVRHLPAELTAEEKEDLLKYFGAQSVRVLSDKGRLKHTAFATFPNEKAAIKALTRLHQLKLLGHTLVVEFAKEQDRVHSPCPTSGSEKKKRSDDPVEDDKEKKELGYLTVENGIAPNHGLTFPLNSCLKYMYPPPSSTILANIVNALASVPKFYVQVLHLMNKMNLPTPFGPITARPPMYEDYMPLHAPLPPTSPQPPEEPPLPEEDEELSSEESEYESTDDEDRQRMNKLMELANLQPKRPKTIKQRHVRKKRKIKDMLNTPLCPSHSSLHPVLLPSDVFDQPQPVGNKRIEFHISTDMPAAFKKDLEKEQNCEEKNHDLPATEVDASNIGFGKIFPKPNLDITEEIKEDSDEMPSECISRRELEKGRISREEMETLSVFRSYEPGEPNCRIYVKNLAKHVEEKDLKYIFGRYVDFSSETRRIMFDIRLMKEGRMKGQAFVGLPNEKAAAKALKEANGYVLFGKPMVVQFARSARPKQDPKEGKRKC
What is the function of this protein?
Participates in pre-mRNA U12-dependent splicing, performed by the minor spliceosome which removes U12-type introns.  U12-type introns comprises less than 1% of all non-coding sequences.  Binds to the 3'-stem-loop of m(7)G-capped U12 snRNA (By similarity).
What are the official names of this protein?
RNA-binding region-containing protein 3, RNA-binding motif protein 40, RNA-binding protein 40.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYK_KINRD
Sequence: MVDGPDEEFEDVPEQVRVRREKRDRILAAGGEAYPVSVPRTDSLADLRERYAHLEAGEETTDQVGVTGRVVFLRGTGKLAFATLQEGDGTRLQVMVSRDGVGEDALAAWKSDVDLGDIVFVHGNVISSRRGELSVLADSWRMASKSLRPLPVLHKELSEETRVRQRYVDLIVREAARTNVRARSNVVRALRRTLEDRGFLEVETPMLQTLHGGASARPFVTRSNAFDTELYLRIAPELFLKRCVVGGIERVFEINRNFRNEGADSTHSPEFAMLETYQAWGDYDSIGELTRALVQNAATEAFGTQLVTLADGSEYDLGGEWTSISMYPSLSASLGEEITPETPREHLIGIAERLGISVDTVRWTHGKLVEELWEHRIADSLHSPTFVRDFPVETSPLVRGHRELPGVVEKWDLYVRGFELATGYSELVDPVVQRERFVEQARLADLGDDEAMRIDEDFLRAQEHGMPPTGGMGMGIDRLLMALTGLGIRETITFPLVKPR
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_PSEPW
Sequence: MPKMKTKSGAAKRFLKTATGFKHKHAFKSHILTKMSTKRKRQLRGSSLLHPSDVAKVARMLRVR
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: PURA_ECOSM
Sequence: MGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMKELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAEKLKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLDVLDGLKEVKLCVAYRMPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPFDA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FUCO1_ARATH
Sequence: MNSQITLFFFFFSILSLSQISNSSSLLKPHPCPILPLPSSQQLQWQLGSMAMFLHFGPNTFTDSEWGTGKANPSIFNPTHLNASQWVQIAKDSGFSRVILTAKHHDGFCLWPSEYTDYSVKSSQWRNGAGDVVAELASAAKEAGIGLGLYLSPWDRHEQCYGKTLEYNEFYLSQMTELLTKYGEIKEVWLDGAKGDGEKDMEYFFDTWFSLIHQLQPKAVIFSDAGPDVRWIGDEAGLAGSTCWSLFNRTNAKIGDTEPSYSQEGDGYGQDWVPAECDVSIRPGWFWHASESPKPAVQLLDIYYNSVGRNCLFLLNVPPNSSGLISEQDIKVLEEFSEMKNSIFSNNLARKAFVNSSSIRGDQSSQFGPKNVLEEGLDKYWAPEENQNEWVLYLEFKDLVSFNVLEIREPIHMGQRIASFHLETRKTGSGEWERVVSGTTVGNKRLLRFLNVVESRSLKLVVDKARTDPLISYLGLYMDKFSGSSRNTTKITITRTLKEEQQLHDL
What is the function of this protein?
Hydrolyzes both 3- and 4-linked fucoses in Lewis determinants.  Not active on neither 2-linked fucose nor on fucose in alpha-1,3-linkage to the innermost GlcNAc.
What are the official names of this protein?
Alpha-L-fucosidase 1, Alpha-1,3/4-fucosidase, AtFUC1, Alpha-L-fucoside fucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 29 family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: SIM10_HUMAN
Sequence: MEALGSGHYVGGSIRSMAAAALSGLAVRLSRPQGTRGSYGAFCKTLTRTLLTFFDLAWRLRKNFFYFYILASVILNVHLQVYI
What are the official names of this protein?
Small integral membrane protein 10.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: TF2B_CAEEL
Sequence: MSAPVQCPIHPDVHLIEDHRAGDLVCPACGLVVGDRLVDVGTEWRSFSNERSGNDPSRVGAPENPLLSGGDLSTTIAVGFGGSDSDNSLANAQRKSMNNTDRQMTAAMSLIREMSERIHLPRNIQDSASRIFKDVLESKALRGKNNEAQAAACLYIACRKDGVPRTFKEICAVSRVSKKEIGRCFKIIVRSLETNLEQITSADFMSRFCGNLSLPNSIQAAATRIAKCAVDMDLVAGRTPISIAAAAIYMASQASAEKRSAKEIGDVAGAAEITVRQTYKLLYPKALELFPKDFRFVTPIDALPNS
What is the function of this protein?
General transcription factor that plays a role in transcription initiation by RNA polymerase II (Pol II) (By similarity).  Involved in the pre-initiation complex (PIC) formation and Pol II recruitment at promoter DNA (By similarity).  Essential for early embryonic development (PubMed:11566890).
What are the official names of this protein?
Transcription initiation factor IIB, General transcription factor TFIIB.
What is the protein family that this protein belongs to?
Belongs to the TFIIB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CLPP_NITOC
Sequence: MIDSLNTLVPMVVEQTARGERAYDIYSRLLKERVVFLVGPVEDHMANLVVAQLLFLESENPDKDIHLYINSPGGSVTAGLSIYDTMQFIKPDVSTLCVGQAASMGAVLLAGGAGGKRHCLPHSRLLIHQPLGGFQGQATDIDIHAREILLVRERLNHILAKHTGQPIEKIQHDTDRDYFMSATESLAYGLVDSVLKQRAEISL
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F16PA_GEOUR
Sequence: MFSEPGKSKFQIDLRRHLRSQNICDNLIHLICEIAEASKYVINAVRTGDLGVAGTSNLYGEEQLALDVLSDRIMRKRLIHSGVVCNIASEEMDEIYQVTTDSNGLYSVAYDPLDGSSLVDVNLAVGTIVSIFSGCDLLQEGRKQVAAMYILYGPRVSLVYTVGDGVHEFTMNQLMEFNLTRENIRMQPDGNIYSPGGLRNKYNEGDEKFIRYLEAKGCKLRYSGGFVPDINQVLMKGKGLFMYPALNGSPNGKLRLLFELNPMAFIIEHAGGAATNGKIPILDIKPEGLDQRAPIYIGCVEDVNRAMEYVYKS
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y7004_CUPNH
Sequence: MQPKRSQAFVDTMHPLPEVLPSVWWHPGVSRRVSVHSGCFLSSHYLKPLGLSQPHARCLLRIAKRRLHEIINWNSRQAWKGACSSFRVSVARRTVHGSLFR
What are the official names of this protein?
Uncharacterized protein PHG004, ORF4.
Protein: CBIX_PRIMG
Sequence: MGGHYMKSVLFVGHGSRDPEGNDREFISTMKHDWDASILVETCFLEFERPNVSQGIDTCVAKGAQDVVVIPIMLLPAGHSKIHIPAAIDEAKEKYPHVNFVYGRPIGVHEEALEILKTRLQESGENLETPAEDTAVIVLGRGGSDPDANSDLYKITRLLWEKTNYKIVETSFMGVTAPLIDEGVERCLKLGAKKVVILPYFLFTGVLIKRLEEMVKQYKMQHENIEFKLAGYFGFHPKLQTILKERAEEGLEGEVKMNCDTCQYRLGIMEHIDHHHHHDHDHDHDHGHHHHDHHHDHHEDKVGELK
What is the function of this protein?
Chelates cobalt to the cobalamin precursor as part of the anaerobic pathway to cobalamin biosynthesis.
What are the official names of this protein?
Sirohydrochlorin cobaltochelatase, CbiXL.
What is the protein family that this protein belongs to?
Belongs to the CbiX family. CbiXL subfamily.
Protein: DAPF_XANC5
Sequence: MSADGRSGRLRFTKMHGAGNDFVVLDLRDGTPPPDAALAAQLADRHFGVGCDQILTIEAPRSEGAVAAYGIWNSDGSAARQCGNGARCVAAWLVRDGTAQGERFIIDSPMSAHAVERLDGDRYAVAMGVPQFEPAQIPLAGFAHARDEYALPVHGETVRFGAVSMGNPHAVVEVGRVDAAPVERVGALLQQNAAFPDSVNVGFVQVVDPAHVRLRVFERGVGETLACGSGACAAAVVLMQRGRVERDVQVSLPGGELRIRWPGDQEQVVMSGPAVFVFDGEWNR
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAY_VESOH
Sequence: MFLELINFITQFDTKFNVLNYLTIRALLAMLSALFIGLMLGRIFIKRLQQCHINQVIRTDGPKSHLIKVGTPTMGGILILFAFIVSILIWGDWSNIYLWIIIVTSIIFSAIGFTDDYLKIKHKSSNGLSSSIKFLTQSLSAIVISTWIILISQKTTQPQLLIPFFNDIILPLSVFDFLILSYFVIVGSSNAVNLTDGLDGLAIMSVILISGALAIFAYFSGNYNFSNYLNMPYITGINELFIICAALIGSSLGFLWFNAYPAEIFMGDVGSLSLGAILAVIAILIRQEILLFIMGGVFVAETLSVIIQVGYYKLYKKRIFLMTPLHHHFEKQNISEPKIIVRFWIVTLILVLIGLASIKIH
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: E4PD_ECOLU
Sequence: MTVRVAINGFGRIGRNVVRALYESGRRAEITVVAINELADAAGMAHLLKYDTSHGRFAWEVRQERDQLFVGDDAIRVLHERSLQSLPWRELGVDVVLDCTGVYGSREHGEAHIAAGAKKVLFSHPGSNDLDATVVYGVNQDQLRAEHRIVSNASCTTNCIIPVIKLLDDAYGIESGTVTTIHSAMHDQQVIDAYHPDLRRTRAASQSIIPVDTKLAAGITRFFPQFNDRFEAIAVRVPTINVTAIDLSVTVKKPVKANEVNLLLQKAAQGAFHGIVDYTELPLVSVDFNHDPHSAIVDGTQTRVSGAHLIKTLVWCDNEWGFANRMLDTTLAMATVAFR
What is the function of this protein?
Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
What are the official names of this protein?
D-erythrose-4-phosphate dehydrogenase, E4PDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_XANOR
Sequence: MSVVVRHDWDHKELQALFDLPFPELLHRAASVHRAHFDPAEVQVSTLLSVKTGGCPEDCAYCPQAQRYDTGVTAQKLLETEEVVAKARQAKAAGASRFCMGAAWRSPKERDIPKVAAMIREVKAMGLETCATLGMLDAGQARALKDAGLDYYNHNLDTAPDYYDTIIHTRQYQDRLNTLEHVRDVGLKTCCGGIVGMGETRDHRIGLLLALATLPAHPDSVPINQLVQVPGTPLHGTQQLDPFEFVRMIAVARIAMPKSMVRLSAGREAMSDELQALCFLAGANSIFYGEKLLTTGNPDTERDQTLFQRLGLRPMQITVDAAEHDHPATVHAEITRSAACEHTA
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: YBEY_SYNSC
Sequence: MELDLALDREEGALQASEIGDLLDETVWLQQLEHWLQIVCGDESLDCPTLVRSAEELSLGLRFIDDATIADLNSTWRQKTGPTDVLSFAALDDAGDWMEGPSIELGDIVVSLETARRQAQEQGHSLQQELRWLVSHGLLHLLGWDHPDEKSLATMLALQERLLGDG
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMPA_TREPH
Sequence: MKLKSLVFSLSALFLVLGFTGCKSKAQAKAEQEAQERKAFMAENAKIEKRLMQAKNAATEAEANVYYPEKFAQIEDLEKQSSEAKEQDDLKKANSLGSAAADKYETLANKMKIANQRSKIEANKLAKYDEESYRLGEEAEKKIDGLYKSDSVAALQTSNESLMYYNKVIDAGYKSLSQDAKKTADDAKAALTAVKVAASLKPQQEEADGIYAKAEEAENSAQYEQSYGGYTSAAQAYNDLTQIIKAKRLEAQKAMQAAKTKQELSAKLANEADKESPLPENAEGFSKEPIEVEPLPTDVLNAPQDEKAEETVPVEEMNENSSEEVNGNAEKIESTEEPIEGGVQ
What are the official names of this protein?
Treponemal membrane protein A, Antigen TmpA, Membrane protein A.
What is the protein family that this protein belongs to?
To T.pallidum TmpA.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.