PharMolix/UniProtQA huggingface dataset:
Protein: CU07_LOCMI
Sequence: GVISAGYAAAPAYAAAPAYAAAAAPIEYDPNPHYSFEYSVSDAHTGDQKAQHETREGDVVQGSYSLVEPDGSVRTVEYTADPHNGFNAVVHRQAGAHPAPAPVAVAKVAAPVAYAAAPAYAAAPAYGYKHL
What is the function of this protein?
Component of the cuticle of migratory locust which contains more than 100 different structural proteins.
What are the official names of this protein?
Cuticle protein 7, LM-ACP 7, LM-7.
Protein: COX2_LUMTE
Sequence: MPNWGQVMFQDAASSVMLQLVSFHDHALLVLTLVLTVVGYALLALMLNKQVNRYIMEAQTVETIWTILPALILLVLALPSLRILYITDEVSQPSITVKTIGHQWYWSYEYTDFLNVEMDSYMLPTSDLLPGDYRLLEVDNRMVVPMQLEIRMLITAADVIHSWTVPALGVKVDAVPGRLNQIGFTTTQPGVFYGQCSEICGANHSFMPIAVEAINTKSFMSWVSNFKP
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RS15A_PARLI
Sequence: MVRMNVLAAALRCICNAEKRCKRQVLIRPCSKVTIKFLMVMIKHGYIGEFEVVDDHRGGKIIVNLNGRLNKCGVISPRFDVPINDMEKWTSNLLPSRQFGYVVLTTSGGIMDHEEARRKHVGGKILGFFF
What are the official names of this protein?
40S ribosomal protein S15a, Ribosomal protein S24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: MAOP3_ARATH
Sequence: MGTNQTQISDEYVTGNSSGVGGGISDVYGEDSATLDQLVTPWVTSVASGYTLMRDPRYNKGLAFTDKERDAHYITGLLPPVVLSQDVQERKVMHNLRQYTVPLQRYMALMDLQERNERLFYKLLIDNVEELLPVVYTPTVGEACQKYGSIYRRPQGLYISLKEKGKILEVLKNWPQRGIQVIVVTDGERILGLGDLGCQGMGIPVGKLSLYTALGGIRPSACLPITIDVGTNNEKLLNNEFYIGLKQKRANGEEYAEFLQEFMCAVKQNYGEKVLVQFEDFANHHAFELLSKYCSSHLVFNDDIQGTASVVLAGLIAAQKVLGKSLADHTFLFLGAGEAGTGIAELIALKISKETGKPIDETRKKIWLVDSKGLIVSERKESLQHFKQPWAHDHKPVKELLAAVNAIKPTVLIGTSGVGKTFTKEVVEAMATLNEKPLILALSNPTSQAECTAEEAYTWTKGRAIFASGSPFDPVQYDGKKFTPGQANNCYIFPGLGLGLIMSGAIRVRDDMLLAASEALASQVTEENFANGLIYPPFANIRKISANIAASVGAKTYELGLASNLPRPKDLVKMAESCMYSPVYRNFR
What are the official names of this protein?
NADP-dependent malic enzyme 3, AtNADP-ME3, NADP-malic enzyme 3.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_STRP2
Sequence: MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: SEC23_ASPCL
Sequence: MDYEALKDQWSDVEERDGIRLSWNTFPSTRMEASRLVVPIAAVYTPLKEKPESPLLQYEPVTCKAPCRAVLNPYANVDVRARIWICPFCLMRNPLPPHYKDITENAIPPELHPQSTTIEYQLARPAPAPPIFVYVVDTCQEEDSLKALKDTLILSLSLLPPNALVGLITFGTMAQVHELGYTECAKSYVFRGSKDYAAKQVQEMLGLLAPGPRPNVPQQPARPPVGPAARFLLPVQQAEFQITNVLEQLQRDPWPVANDKRPLRCTGVALSVAVGLLETSFQNAGGRVMVFTSGPATEGPGHVVGPELKEPIRSHHDIDRDNIKYYKKAVKFYDALAKRAANNGHVVDIFAGCLDQVGLLEMKNLSNFTGGHMLLTDSFTSSQFKQSFVRVFDKDANDNLLMGFNASLEVLTTKELKVTGLIGHAVSLNKKSSSVGETECGIGNTCAWKMCGIDPASSYGVYFEIANQGGPAAVQPGPQRGMMQFLTYYQHSSGHYHLRVTTVARPLSGPTGDPALAQSFDQEAAAVLMARIAVYKADVDDGPDVIRWVDRMLIRLCSRFADYRKDDPTSFRLEKNFTLYPQFMFHLRRSQFLQVFNNSPDETAFYRHVLNHEDVGDSLVMIQPTLDSYSLEHEGSQPVLLDSASIQPTHILLLDTFFHILIFHGETIAEWRKAGYQDQEGYENLKALLEQPKEDARELIADRFPLPRFIVCDAGGSQARFLLSKLNPSTTHTTGGYGGGVTSQTIFTDDVSLQTFMDHLMK
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
What are the official names of this protein?
Protein transport protein sec23.
What is the protein family that this protein belongs to?
Belongs to the SEC23/SEC24 family. SEC23 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ALLT_AGRIP
Sequence: MNFSMHLVLAVAAAACLCVVTAAPEGRLTRTKQQRPTRGFKNVEMMTARGFGKRDRPHTRAELYGLDNFWEMLEAAPEREGQESTDEKTLESIPLDWFVNEMLNNPDFARSVVRKFIDLNQDGMLSSEELLRNVA
What is the function of this protein?
Neuropeptide stimulator of juvenile hormone synthesis.
What are the official names of this protein?
Allatotropins.
What are the subcellular locations of this protein?
Secreted.
Protein: SPA31_BOVIN
Sequence: MRAERTSFLLALGLLVAGIRSVHCLPENVVVKDQHRRVDGHTLASSNTDFAFSLYKQLALKNPNKNVILSPLSVSIALAFLSLGARGSTLTEILEGLKFNLTEIQEKEIHHSFQHLLQALNQPSNQLQLSVGNAMFVQEELKLLDKFIEDAQVLYSSEAFPTNFRDSEAARSLINDYVKNKTQGKIEELFKYLSPRTELVLVNYIYFKAQWKTPFDPKHTEQAEFHVSDNKTVEVPMMTLDLETPYFRDEELGCTLVELTYTSNDSALFILPDEGKMRDLEAKLTPETLTRWRNSLQPRRIHELYLPKFSIKSNYELNDILSQLGIRKIFANADLSGITGTADLVVSQVVHGAALDVDEEGTEGAAATGISMERTILRIIVRVNRPFLIAIVLKDTQSIIFLGKVTNPSEA
What is the function of this protein?
Potent inhibitor of the serine proteases elastase and trypsin.  Moderately inhibits the serine proteases plasmin and chymotrypsin, and the thiol protease proenkephalin-processing enzyme.  Does not inhibit the serine proteases cathepsin G, furin, kallikrein, thrombin, tissue plasminogen activator and urokinase, or the cysteine proteases cathepsin B, cathepsin L and papain.
What are the official names of this protein?
Serpin A3-1, Endopin-1A, Muscle endopin-1A, mEndopin-1A.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, chromaffin granule. Secreted. Note=In longissimus muscle myocytes highest levels are found between the plasma membrane and the myofibrils and lower levels are found within the myofibrils. Localized to the chromaffin granules of the adrenal medulla and secreted in response to nicotine or KCL depolarization.
Protein: ILVD_LISMF
Sequence: MRSDKIKKGVEQAPARSLLHATGQIKSPGDMDKPFIAICNSYIDIVPGHVHLRELADVAKEAIREAGGIPFEFNTIGVDDGIAMGHIGMRYSLPSREVIADAAETVINAHWFDGVFYIPNCDKITPGMLLASVRTNVPAIFCSGGPMKAGLSAHGKALTLSSVFEAVGAFKDGSMSQEDFLDMEANACPTCGSCAGMFTANSMNCLMEILGMAVPGNGTTLAVSDARRDLIRESAFHLMDLVKKDIRPRDIITKDAIDDAFALDMAMGGSTNTVLHTLALANEAGIEDYDLERINDIAKRVPYLSKIAPSSSYSMHDVHEAGGVSAIVKELVDLGGAIHPDRITVTGKTIRENVADAKINNTDVIHPKENPYSPVGGLSMLFGNIAPKGAAIKVGGVDPSVQVFKGEAICFSSHDEAVEAIDNHTVREGHVVVIRYEGPKGGPGMPEMLAPTSSIVGRGLGKDVALITDGRFSGATRGIAVGHISPEAAAGGPIALVHDGDIITIDLPNRTLNVDVSDEVLEERRKELPKFKAKVKTGYLARYTALVTSAHTGGILQIPEDLID
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: COI1A_ORYSI
Sequence: MGGEVPEPRRLNRALSFDDWVPDEALHLVMGHVEDPRDREAASRVCRRWHRIDALTRKHVTVAFCYAARPARLRERFPRLESLSLKGKPRAAMYGLIPDDWGAYAAPWIDELAAPLECLKALHLRRMTVTDADIAALVRARGHMLQELKLDKCIGFSTDALRLVARSCRSLRTLFLEECHITDKGGEWLHELAVNNSVLVTLNFYMTELKVAPADLELLAKNCKSLISLKMSECDLSDLISFFQTANALQDFAGGAFYEVGELTKYEKVKFPPRLCFLGLTYMGTNEMPVIFPFSMKLKKLDLQYTFLTTEDHCQIIAKCPNLLILEVRNVIGDRGLEVVGDTCKKLRRLRIERGDDDPGLQEEQGGVSQLGLTAVAVGCRELEYIAAYVSDITNGALESIGTFCKNLYDFRLVLLDRERQVTDLPLDNGVCALLRNCTKLRRFALYLRPGGLSDDGLSYIGQYSGNIQYMLLGNVGESDHGLIRFAVGCTNLQKLELRSCCFSERALSLAVLQMPSLRYIWVQGYRASQTGLDLLLMARPFWNIEFTPPSPESFNHMTEDGEPCVDSHAQVLAYYSLAGRRSDCPQWVIPLHPA
What is the function of this protein?
Involved in jasmonate (JA) signaling.  Required for jasmonate signaling in plant defense responses.  Can complement Arabidopsis coi1-1 mutant and restore jasmonate signaling.  Required for JA-regulated defense responses to infestation by the leaffolder Cnaphalocrocis medinalis.  May act on an initial response of jasmonate-regulated gene expression toward drought tolerance as part of a BHLH148-TIFY11D/JAZ12-COI1A complex (By similarity).  Component of SCF(COI1) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins, including TIFY/JAZ family (By similarity).
What are the official names of this protein?
Coronatine-insensitive protein homolog 1a.
Protein: HMT3_ARATH
Sequence: MGSFVKEETSSLMTDFLEKCGGYAVVDGGFATELQRHGADINDPLWSAKCLITSPHLVTKVHLDYLESGANIIITASYQATIQGFVAKGLSVGEAENLLRRSVEITYEAREIFYNRCTKGSWDFAYAGKASRRPILVAASVGSYGAYLADGSEYSGIYGDSVSKETLKDFHRRRVQILAKSGADLIAFETIPNKLEAEAYADLLEEEDIDIPAWFSFTSKDGVSVPRGDSVVECAKVADSCKNVVAIGINCTAPRYIHALIISLRQMTRKPIVVYPNSGEVYDGLNKKWIKSEGESEEDFVSYVSKWRDAGASLFGGCCRTTPNTIRAIAKVLSDEPSAASKPKFGQ
What is the function of this protein?
Catalyzes methyl transfer from S-methylmethionine (SMM) to adenosyl-L-homocysteine (AdoMet).  SMM degradation (by HMT-1, HMT-2 and HMT-3) and biosynthesis (by MMT1) constitute the SMM cycle in plants, which is probably required to achieve short term control of AdoMet level.
What are the official names of this protein?
Homocysteine S-methyltransferase 3, S-methylmethionine:homocysteine methyltransferase 3, AtHMT-3, SMM:Hcy S-methyltransferase 3.
Protein: PURA_MALGO
Sequence: MASMPKPNQSARGRVTVVLGSQWGDEGKGKLTDMLAGEMDICARCAGGNNAGHTIVANSGPDNVKTKFDFHLLPSGLVNPKCIGFIGSGVVMHVPSFFSELDTIEKKGLKCDNRLFVSDRTHLVFDFHQVVDGLKEVELGGSSIGTTKKGIGPAYSSKASRSGLRVHHLYDFDTFAAKFRKLVEGRFKRYGNFEYDTEGEIARYRAFAERLRPFVVDGVTFIHSMLSSNRRVLVEGANALMLDLDYGTYPFVTSSSTGIGGVCTGLGIPPQCIGGVIGVMKAYTSRVGAGPFPTELNDEIMTHLQEVGAEYGTTTGRRRRCGWLDLVMMRYSCLINGYTCLNLTKLDVLDNLPEIKVATTYMLGDKELSSFPADLNILAKVDVQYKTFKGWRGPISNCTSYEQLPDTCREYIEFIENFLGVHIEWIGVGPGREAMVHRPLPPHEM
What is the function of this protein?
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_BACNA
Sequence: MFKLDLQPTEKLFIPFITAGDPVPEVSIELAKSLQKAGATALELGVAYSDPLADGPVIQRASKRALDQGMNIVKAIELGGEMKKNGVNIPIILFTYYNPVLQLNKEYFFALLQENHIDGLLVPDLPLEESNSLQEECKSHEVTYISLVAPTSESRLKTIIEQAEGFVYCVSSLGVTGVRNEFNSSVYPFIRTVKNLSTVPVAVGFGISNREQVIKMNEISDGVVVGSALVRKIEELKDRLISAETRNQALQEFEDYAMAFSGLYSLK
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: RECA_SHEPC
Sequence: MKVDPNKEKALAAVLSQIEKQFGKGSIMKLGEDRSMDVETISTGSLSLDVALGAGGLPMGRIVEIYGPESSGKTTLTLEVIAAAQREGKTCAFIDAEHALDPIYAKKLGVDIDNLLCSQPDTGEQALEICDALTRSGAVDVIVVDSVAALTPKAEIEGEIGDSHMGLAARMMSQAMRKLAGNLKQSNTLLIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRTGAIKDGDEVVGNETRVKVVKNKVAAPFKQAEFQILYGQGINRTGELVDLGVAHKLIEKAGAWYSYKGDKIGQGRANAGKYLTENPAIAAEIDKTLRELLLSNPSALASSASDDESTEGNIDLETGEIF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBSB_PARMW
Sequence: MDQTLIQEILEVVEQAAIASAKLSGKGLKNEADAAAVEAMRKRMGQIQMQGRIVIGEGERDEAPMLYIGEEVGSGTGPGVDFAVDPCEGTNLCAFNQRGSMAVLAASDRGGLFNAPDFYMKKLAAPPAAKGKVDIRKSATENIKILSECLGLAVDELTIVVMDRARHKDLIAEIRATGARIQPISDGDVQAAIACGFAGTGTHCLMGIGAAPEGVISAAAMRALGGHFQGQLVYDPAVAQTSEWADMTKEGNLARLAEMGITDPDKVYEAEELACGEHVCFAGSGITDGLLFHGVKFERDCTRTSSLVISNLDNTCRFTNTVHIKDGAQSIALS
What is the function of this protein?
Catalyzes the hydrolysis of fructose 1,6-bisphosphate (Fru 1,6-P2) and sedoheptulose 1,7-bisphosphate (Sed 1,7-P2) to fructose 6-phosphate and sedoheptulose 7-phosphate, respectively.
What are the official names of this protein?
D-fructose 1,6-bisphosphatase class 2/sedoheptulose 1,7-bisphosphatase, FBPase class 2/SBPase.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 2 family.
Protein: RR4_HYPLA
Sequence: MSRYRGPRVRIIRRLGALPGLTNKTPQLKSSSINQSTSNKKISQYRIRLEEKQKLRFHYGITERQLLNYVRIARKAKGSTGEILLQLLEMRLDNVIFRLGMTPTIPGARQLVNHRHILVNGYIVDIPSYRCKPQDFITIKNQRKSEAIISKNIEFYQKYKIPNHLTYSSLEKKGLVNQILNRKSIGLKINELLVVEYYSRQA
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FLA2_CAMJU
Sequence: MGFRINTNVAALNAKANADLNSKSLDASLSRLSSGLRINSAADDASGMAIKDSLRSQANTLGQAISNGNDALGILQTADKAMDEQLKILDTIKTKATQAAQDGQSLKTRTMLQADINRLMEELDNIANTTSFNGKQLLSGNFINQEFQIGASSNQTVKASIGATQSSKIGLTRFETGSRISVGGEVQFTLKNYNGIDDFKFQKVVISTSVGTGLGALADEINKNADKTGVRATFTVETRGMGAVRAGATSDDFAINGVKIGKVDYKDGDANGALVSAINSVKDTTGVEASIDENGKLLLTSREGRGIKIEGNIGRGAFINPNMLENYGRLSLVKNDGKDILISGTNLSAIGFGTGNMISQASVSLRESKGQIDANVADAMGFNSANKGNILGGYSSVSAYMSSTGSGFSSGSGFSVGSGKNYSTGFANTIAISAASQLSAVYNVSAGSGFSSGSNLSQFATMKTSAGNTLGVKDETAGVTTLKGAMAVMDIAETAITNLDQIRADIGSVQNQVTSTINNITVTQVNVKAAESQIRDVDFAAESANYSKANILAQSGSYAMAQANSVQQNVLRLLQ
What is the function of this protein?
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
What are the official names of this protein?
Flagellin A.
What is the protein family that this protein belongs to?
Belongs to the bacterial flagellin family.
What are the subcellular locations of this protein?
Secreted. Bacterial flagellum.
Protein: E2F8_RAT
Sequence: MENQKENLFSEPHKRGLVKSPLQESSKANVVLAEIQPDLGPLTTPTKPKEVSQGEPWTPTANLKMLISAVSPEIRSRDQKRGLSDNRSGLPEARDCLHEPQAKTNEKSQPSRKEKSLGLLCHKFLARYPKYPNPAVNNDICLDEVAEELDVERRRIYDIVNVLESLHMVSRLAKNRYTWHGRHNLTKTLGTLKSVGEENKYAEQIMMIKRKEHEQEFDFIKSCGLEDHHVIKSTAGQNGHSDMCFVELPGVEFRAASANSRKDKSLRVMSQKFVMLFLVSTPQIVSLEIAAKILIGEDHVEDLDKSKFKTKIRRLYDIANVLSSLDLIKKVHVTEERGRKPAFKWTGPEISPNNSGSSPVMPLTASLEAEQSAKENCAKNLFSTRGKPSFTRHPSLIKLVKSIENDRRKISSAPSSPVKSSKAESSQNSPPVPNKMAQLAAICKMQLEEQSSEPRKRVKVNLTRSGHYKPLAPLDPAVNTELELLAPSLIQPLGMVPLIPSPLSSAVPVILPQAPSGPSYAIYLQPAQAQMLTPPHGLSPTVCPTQSSNATGSKDPTDAPTEKTATDATKPGSLQPAPERQGAKNRSKETTGDRGTKRTGALEDGGPGPIKKPKEDLKALENVPTPTTLFPSGYLIPLTQCPSLGPDPMLSNTENSGTLSPNHRIYGSPIAGVIPVASSELTAVNFPPFHVTPLKLMVSPTSMAAVPVGNSPALSSSHPAPTQNPSSAIVNFTLQHLGLISPGVQMSASPGPGAGTVPLSPRVEADNLSSRQGRATIHDSPVLGQSQLNGQPVAGTGAQQPVPVTPKGSQLVAESFFRTPGGPTKPTSSSFMDFDGANKTSFGTLFVPQRKLEVSTEDVH
What is the function of this protein?
Atypical E2F transcription factor that participates in various processes such as angiogenesis and polyploidization of specialized cells.  Mainly acts as a transcription repressor that binds DNA independently of DP proteins and specifically recognizes the E2 recognition site 5'-TTTC[CG]CGC-3'.  Directly represses transcription of classical E2F transcription factors such as E2F1: component of a feedback loop in S phase by repressing the expression of E2F1, thereby preventing p53/TP53-dependent apoptosis.  Plays a key role in polyploidization of cells in placenta and liver by regulating the endocycle, probably by repressing genes promoting cytokinesis and antagonizing action of classical E2F proteins (E2F1, E2F2 and/or E2F3).  Required for placental development by promoting polyploidization of trophoblast giant cells.  Acts as a promoter of sprouting angiogenesis, possibly by acting as a transcription activator: associates with HIF1A, recognizes and binds the VEGFA promoter, which is different from canonical E2 recognition site, and activates expression of the VEGFA gene (By similarity).
What are the official names of this protein?
Transcription factor E2F8, E2F-8.
What is the protein family that this protein belongs to?
Belongs to the E2F/DP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: IF6_METS3
Sequence: MLRRINIVDNPNIGVFILATDDLAVVPYNLLDEKVKLIEETLEVDAVKSSISGCNLIGSLAVANSNGIVVSPHVLDREVKQFEELGLNVATIPGNYTAVGNIVAANDTGAIVSPFLSDEAVKVIEDTLDVNVESTSMVGSDIIGSLITVTNKGFLMDKNATETEVDFARDVFGVEGDIGTVGRGISLVGACSLANSSGAIVAKESTGPEMARVEEALGFLDDL
What is the function of this protein?
Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.
What are the official names of this protein?
Translation initiation factor 6, aIF-6.
What is the protein family that this protein belongs to?
Belongs to the eIF-6 family.
Protein: TIM9_YEAST
Sequence: MDALNSKEQQEFQKVVEQKQMKDFMRLYSNLVERCFTDCVNDFTTSKLTNKEQTCIMKCSEKFLKHSERVGQRFQEQNAALGQGLGR
What is the function of this protein?
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane.  Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane.  Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.  Compared to TIM10, it may have a strong structural role.
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit TIM9.
What is the protein family that this protein belongs to?
Belongs to the small Tim family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Mitochondrion intermembrane space.
Protein: PLSX_COXBU
Sequence: MLKTIALDAMGGDNGPKVIVPAALSILKKHPKVKLILVGKEDQLALLIPEKNRKSFGQRLEIIHASEEVGMDEPPSQALRTKKNSSMRVAINLVKEGQAHACVSAGNTGALMATARYVLKTLPGIDRPAIIAAFPTKNEREVRVLDLGANVDSTPENLYQFAVMGSILSSAAHNIRNPRIGLLNVGEEEIKGNELVKKANELFETRKTINYIGYVEGNTIFNNIADVVVCDGFVGNAVLKASEGVAQLIKQHAKEAFSEAWWTKLALLPAIPILKRLIRRVDPERYNGATFLGLNGIVVKSHGSANIKAFVCAVEEAIFQVDKNIPQLIKEEVAHILKEFENK
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: DAPB_ECOSE
Sequence: MHDANIRVAIAGAGGRMGRQLIQAALALEGVQLGAALEREGSSLLGSDAGELAGAGKTGVTVQSSLDAVKDDFDVFIDFTRPEGTLNHLAFCRQHGKGMVIGTTGFDEAGKQAIRDAAADIAIVFAANFSVGVNVMLKLLEKAAKVMGDYTDIEIIEAHHRHKVDAPSGTALAMGEAIAHALDKDLKDCAVYSREGHTGERVPGTIGFATVRAGDIVGEHTAMFADIGERLEITHKASSRMTFANGAVRSALWLSGKESGLFDMRDVLDLNSL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIM39_KLULA
Sequence: MYLARSGVFISRIRVLSILNPRFVLLSRRLNHTDSKHYFTDPKTNEIKKPPTFFQHHDSKVNASADDVAQAIAESVRAHKKRRQKVFFSAMLTGIIGVTLGFSISYKVLYKKQESFIPLVPSRKWHRLSAYDAQRVNIDEMKMLGKMRCLSVLTNHEMIREQFGIPLKTDTGEVPSVKSFEVWCEDQDPGVLGIVVRPIDATRDNDSRYHRTHGWHTIPGLFQWRMGTKPIKIRDKFDSFLKFIGVNTGDLLEVINPDREVGDFKYEYPLRKGDSFDGDDDRAMHIWFFGEIDLSQDAMVVFKGKYHVNVKLEQVDLLKKENDQLIRYVLYKNENDKKNG
What are the official names of this protein?
Altered inheritance of mitochondria protein 39, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AIM39 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: Y102_MYCPN
Sequence: MASSTSLGNVGDTTALTPLLRGATTTTTVQLKQTDSNSQDQQKFQKYLNTAQALHQMGVIVPELSQGGWQSQTARHSSTRGLQSAGANRGASLAARTTTTVGVGRRDSTSTTLELPNVITQLYHTSTSQLAYLNGQIVVMGSNAVPSLWYWVVDERTTSGRATWWAKTHLNFGTEVQKNFVENQLGFKSEDNSNTSLTNFKSQGLTQPAYLISGLDVVADHLVFAAFKAGAVGYDMTTDSNASTYNQALTWSTTAGLDSDGGTTTWWRILRG
What are the official names of this protein?
Putative MgpC-like protein MPN_102.
What is the protein family that this protein belongs to?
Belongs to the MgpC family.
Protein: RS13_HAHCH
Sequence: MARIAGVNIPDNKHTEVSLTYIYGIGRTTSRGLCERTGISPQAKVKDLSEEQLDVLRNEIAKMVVEGDLRREVQMNIKRLKDLGCYRGLRHRHSLPVRGQRTKTNARTRKGPRKPIRK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: CCMA_NITMU
Sequence: MPTLEGIDLTCIRGDRKLFSGVNFLLESGGLMQVQGPNGSGKTSLLRMLCGLASPAEGEIRWDGTQIRSLGGDYFGAMTYLGHLGGVKDDLTAIENLRISSALGGVDLDERKAHDALQHMGLGGRELLPAKVLSQGQRRRVTLARLLVCGTVLWILDEPLTALDTSAVKLVQGLIERHLEHGGMIVMTTHQEIEIAGAAIQRLQLT
What is the function of this protein?
Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL3_NITEC
Sequence: MKLGLIGKKVGMTRIFTESGSSVPVTVLDVSKNRVVQIKTAERDGYSAIQLTQGYRRKNRITKALSGHFARAGVEAGKVIKEFRIEQQAINSDLKLGSEINVEIFLTGSKVDVSGVSIGKGYAGTIKRHNFSSSRASHGNSRSHNVPGSIGMAQDPGRVFPGKKMTGRLGGVNSTIQNIEVVRVDTVRGLIFLKGSVPGSKGNGVFIRPSVKHANKQ
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.