PharMolix/UniProtQA huggingface dataset:
Protein: ACCA_AGRFC
Sequence: MHNYLDFEKPISDLEGKIIELKKLADEDESIDTSEEINRLESRVNDAMQDIYSKLNAWQKTQVARHPQRPHFVDYAKSLFTDFTPLAGDRKFSEDAAIQAGLARFNGQPVAIIGQEKGNDTKSRLKHNFGSARPEGYRKAIRVLELADRFSLPVVTLIDTAGAYPGVGAEERGQAEAIARSTEMCLNVKVPIVSVVIGEGGSGGAIAIATGNRVYMLEHSVYSVISPEGAASILWRDSTRAKEAATNMKITSEDLKSLGVIDGIIPEPIGGAHRAPETVISATGDVIAKALADLSQRSGTQLRAERRQKFLDIGRNL
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VRAS_STAS1
Sequence: MNHYFRAIGSMLILVYSTFFAIFFIDKVFVNIMYFQGMFYTQIFGIPVLLFLNLMVILLCIIVGSVLAYKINQQNHWLKDQIERSIEGQTVGINDQNIELYNETIELYQTLVPLNQEVHKLRMKTQNLTNESYNINDVKVKKIIEDERQRLARELHDSVSQQLFAASMMLSAIKETELKAPLDQQIPVLEKMIQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVVDLQKKVPMKVVHDIEEFKVPKGIEDHLFRITQEAISNTLRHSKGTKVTIELFNREEYLLLRIQDNGKGFNVDDKVEQSYGLKNMRERALEIGATFHIVSLPDAGTRIEVKAPLNKEDSNAD
What is the function of this protein?
Member of the two-component regulatory system VraS/VraR involved in the control of the cell wall peptidoglycan biosynthesis.  Probably activates VraR by phosphorylation (By similarity).
What are the official names of this protein?
Sensor protein VraS.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PMP20_SCHPO
Sequence: MVAVGSTLPKVTLWENKPEEVVEFPSQGKFIIVGVPGAFTPPCSSQVPGYIANEKQFAAKGISGIYVVAVNDVFVTKAWKKSFDGGEQSGVHFVADWNGEFTKAFDAGFDASGLLGPLRSKRYAAVVENGKVVKVFIENEVTDVDISSADKVLSSL
What is the function of this protein?
May act as a chaperone rather than a peroxidase.  Has no thioredoxin-dependent peroxidase activity.  Shows weak chaperone activity.
What are the official names of this protein?
Peroxisomal membrane associated protein 20, Peroxiredoxin homolog pmp20, Prx.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. Prx5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MDM12_ASPTN
Sequence: MSIEVDWKTATSGPDGEALAERIRSFIHDKFQQVALPRFIRSVQVHSFDFGTVPPDLEIKDFCEPFADFYEEDEDDETSEVSEELVSAHGNQWHRTHSELNEPPYRDEVTMNQPLRDPFDEGFHPSPLRSPMEHLNPHFLPRAGTPGIPGGTSTIGYHLMSLGGLSGTQTPLAAVAGGTPFANGWTDHNLGPGNRGHASGPAAGAMRQHRPEDIDSSNPTSRPSTSSTLPSHPSGSNRNSGDGSHPEEEHLDDPAEPDHPFRFPKMRERRPEDFQVMCRAKYAGDVRLSLTAEILLDYPMPSFVGLPLKLNITGVTFDGVAVVAYIRKRVNFCFLSAEDADALIGADDQETRDKDDHPRSGLDPTTSPKRQGGLLREIRVESEIGRKEDGKQVLKNVGKVERFVLAQVRRIFEEELVFPSFWTFLI
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  Mdm12 is required for the interaction of the ER-resident membrane protein mmm1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10.  The mdm12-mmm1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The mdm10-mdm12-mmm1 subcomplex further acts in the TOM40-specific pathway after the action of the mdm12-mmm1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 12, Mitochondrial inheritance component MDM12.
What is the protein family that this protein belongs to?
Belongs to the MDM12 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: AGO2_ARATH
Sequence: MERGGYRGGRGDGRGRGGRGYGGGGGGGEQGRDRGYGGGEQGRGRGSERGGGNRGQGRGEQQDFRSQSQRGPPPGHGGRGTTQFQQPRPQVAPQPSQAPASYAGSVGGVAGRGAWGRKPQVPSDSASPSTSTTVVSEPVRVAEVMNLKPSVQVATSDRKEPMKRPDRGGVVAVRRVNLYVNHYKVNFNPESVIRHYDVEIKGEIPTKKVSRFELAMVRDKVFTDNPDEFPLAMTAYDGQKNIFSAVELPTGSYKVEYPKTEEMRGRSYTFTIKQVNVLKLGDLKEYMTGRSSFNPRDVLQGMDVVMKEHPSKCMITVGKSFFTRETEPDEDFRFGVIAAKGYRHTLKPTAQGLSLCLDYSVLAFRKAMSVIEYLKLYFNWSDMRQFRRRDVEEELIGLKVTVNHRKNKQKLTIVGLSMQNTKDIKFDLIDQEGNEPPRKTSIVEYFRIKYGRHIVHKDIPCLDLGKNGRQNFVPMEFCDLVEGQIYPKDNLDKDSALWLKKLSLVNPQQRQRNIDKMIKARNGPSGGEIIGNFGLKVDTNMTPVEGRVLKAPSLKLAERGRVVREEPNPRQNNQWNLMKKGVTRGSIVKHWAVLDFTASERFNKMPNDFVDNLIDRCWRLGMQMEAPIVYKTSRMETLSNGNAIEELLRSVIDEASRKHGGARPTLVLCAMSRKDDGYKTLKWIAETKLGLVTQCFLTGPATKGGDQYRANLALKMNAKVGGSNVELMDTFSFFKKEDEVMFIGADVNHPAARDKMSPSIVAVVGTLNWPEANRYAARVIAQPHRKEEIQGFGDACLELVKAHVQATGKRPNKIVIFRDGVSDAQFDMVLNVELLDVKLTFEKNGYNPKITVIVAQKRHQTRFFPATNNDGSDKGNVPSGTVVDTKVIHPYEYDFYLCSHHGGIGTSKPTHYYTLWDELGFTSDQVQKLIFEMCFTFTRCTKPVSLVPPVYYADMVAFRGRMYHEASSREKNFKQPRGASTSAASLASSLSSLTIEDKAIFKLHAELENVMFFV
What is the function of this protein?
Involved in RNA-mediated post-transcriptional gene silencing (PTGS).  Main component of the RNA-induced silencing complex (RISC) that binds to a short guide RNA such as microRNA (miRNA) or small interfering RNA (siRNA).  RISC uses the mature miRNA or siRNA as a guide for slicer-directed cleavage of homologous mRNAs to repress gene expression.  Associates mainly with siRNAs of 21 nucleotide in length and preferentially recruits small RNAs with a 5' terminal adenosine.  Probably involved in antiviral RNA silencing.  Associates with siRNA derived from cucumber mosaic virus (CMV).  Targeted by turnip yellows virus (TuYV) protein P0 (via F-box-like domain) for probable proteasome degradation and thereby inactivating AGO2 function in RNA silencing.  Required to direct NERD-dependent DNA methylation and silencing.
What are the official names of this protein?
Protein argonaute 2.
What is the protein family that this protein belongs to?
Belongs to the argonaute family. Ago subfamily.
Protein: DHPS_CLOB8
Sequence: MKIGSKEFNIGERTYIMGILNFTPDSFSDGGKFNDIDVAVKHVKEMIDNGADIIDVGGESTRPGYEIVSEEEEISRVVPIIKAIKEDFDIPVSIDTYKAKVAEQAIEAGANLINDIWGFKKDKDMAKVAAKYNVPCCLMHNRDNTEYKNLMEDILNDLKECINIAKDAGVKDENIILDPGIGFGKTYEQNLEAMNNLERIKELGYPILLGTSRKSMIGLALNLPVEERIEGTVATTVIGIMKDACDFVRVHDVLENSRAAKMTDIIVRR
What is the function of this protein?
Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
What are the official names of this protein?
Dihydropteroate synthase, DHPS, Dihydropteroate pyrophosphorylase.
What is the protein family that this protein belongs to?
Belongs to the DHPS family.
Protein: UBP22_BOVIN
Sequence: MDAELVVTPPGCAHLGSFKVDNWKQNLRAIYQCFVWSGSAEARKRKAKSCVCHVCGLHLNRLHSCLHCVFFGCFTKKHIHEHAKSKRHNLAIELMYGGIYCFLCQDYIYDKDIEIIAKEEQRKAWKMQGVGEKFSTWEPTKRELELLKHNPKRRKITSNCTIGLRGLINLGNTCFMNCIVQALTHTPLLRDFFLSDRHRCEMQSPSSCLVCEMSSLFQEFYSGHRSPHIPYKLLHLVWTHARHLAGYEQQDAHEFLIAALDVLHRHCKGDDNGKKANNPNHCNCIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGSSTPFWPLSPGSESSVVNGESHVSGTTTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKKLPIVACFHLKRFEHSAKLRRKITTYVSFPLELDMTPFMASSKESRMNGQYQQPTDSLNNDNKYSLFAVVNHQGTLESGHYTSFIRQHKDQWFKCDDAIITKASIADVLDSEGYLLFYHKQFLEYE
What is the function of this protein?
Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA.  Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator.  Recruited to specific gene promoters by activators such as MYC, where it is required for transcription.  Required for nuclear receptor-mediated transactivation and cell cycle progression (By similarity).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 22, Deubiquitinating enzyme 22, Ubiquitin thioesterase 22, Ubiquitin-specific-processing protease 22.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. UBP8 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL32_BACC0
Sequence: MAVPFRRTSKTVKRKRRTHFKLSVPGMVECPSCGEAKLAHRVCKACGTYKGKEVISK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: EFGM_ASPNC
Sequence: MRTPTLARLPCRAVSGLTRSSARLQSQNFLTRRCASTAVLRSPTLAPAYQSALSKHFQQRRNASSTAAAVLEAAAANPDTLSQEAIIENLDPVEAARLSRVRNIGIAAHIDSGKTTCTERVLFYTGRIKAIHEVRGRDAVGAKMDSMDLEREKGITIQSAATFCDWVKKDAEGKEQKYHLNLIDTPGHIDFTIEVERALRVLDGAVMILCAVSGVQSQTITVDRQMRRYNVPRISFVNKMDRMGANPFKAVDQINKKLKIPAAAVQVPIGAEDEFEGVVDLLRMKAIYNRGPSGEELFETDEIPEKVKALAEERRQMLIETLADVDDEIAEIFLMEEVPTEDQIRQAIRRATINLKFTPVFMGSALANKSVQPMLDGVIDYLPNPSEVQNLALDKKRNEASVKLVPYNSLPMVGLAFKLEESNFGQLTYIRVYQGTLRKGSFVYNARNDKKVKIPRIVRMHSNEMEDVTEVGAGEICAVFGVECASGDTFTDGQLGYTMSSMFVPEPVISLSIKPKNNKDGANFSKAMARFQREDPTFRVTFDAESEQTLISGMGELHLEIYLERMRREYRVDCETGPPQVAYRETLGERVEFDHLLKKQSGGPGDYARVVGWMEPTGNLGENVFEEQIVGGSISEKFLFACEKGFHLSCDKGPLIGHKVLGTKMVINDGATHMTDSSEMAFKNATQQAFRKAFKESNPAVLEPIMKTVVTAPSEFQGDVIALLNKRNATINDSEVGVDEFTVYADCSLNGMFGISSHLRAATQGKGEYTMEFSHYERAPPHLQKDLIAKYQKAQADRHKK
What is the function of this protein?
Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, mitochondrial, EF-Gmt, Elongation factor G 1, mitochondrial, mEF-G 1, Elongation factor G1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: STS9_POSPM
Sequence: MVRTRPTYIYLPDTAAGWPFPRTVNPYYEETKAESEAWISSLYPFDAYVQKKFNACDFTLLASMAYPWLSKDHIRTGADLMMLFFVFDEYSDVASVKDAQEMVDIVMDALRNPHKPRPKDENILGEIAKQFWERGVKTASAPSARRFVDYFEGYLKSVVEQAQDREHNRIRSIAEYFDVRRLTVGARPSYALMELGMNIPDEVWEDPAMEIMAVCVTDMIILDNDMLSWNVEQSRGDDAHNIVRIVMEANKTDVASAMKWVEDYHNLLKKTFLDVYNSVPSWGPEVDAQVQEYARGLGNWVICNISWSFESARYFGKEGRRIREERVVAILDKPVLVGVLESDA
What is the function of this protein?
Terpene cyclase that catalyzes the cyclization of farnesyl diphosphate (FPP) to a single major sesquiterpene scaffold whose chemical structure is still unknown.
What are the official names of this protein?
Sesquiterpene synthase 9, Terpene cyclase 9.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: MOMT_CATRO
Sequence: MELQSSEIRNAQAHFFTQVFSFTSMSSLKCAVQLGIPDAIHSHGKPMALSDLTNSLPINPSKAPYIYRLMRILVAAGYFSEEEKNVYSLTPFTRLLLKNDPLNSISMVLGVNQIAELKAWNAMSEWFQNEDLTAFETAHGKNFWDFGAEDKYGKNFDGVMAADSILVSKMLIPEFNYLFEGLDSLVDVGGGTGTIAKAIAKSFPDLKCTVFDLPHVVANLESTENLEFVGGDMFEKIPSANAILLKWILHDWKDEECVKVLKMCRKAIPEKEKGGKVILIETVLMDSKKHENEEAVKAQISSDIDMMVFFTAKERTEEEWATLFREAGFSGYKIFPMIDFRSPIEVYP
What is the function of this protein?
Methylates myricetin and dihydromyricetin at 2 sites.  Inactive towards 16-hydroxytabersonine, the phenylpropanoids 5-hydroxyferulate, caffeate and their CoA-esters, flavones and flavanones possessing 2 or 3 B-ring hydroxyl groups.
What are the official names of this protein?
Myricetin O-methyltransferase, CrOMT2, Flavonoid O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. COMT subfamily.
Protein: DAPA2_CLOAB
Sequence: MKIEGVLIPLITPFKDGKVDLASYEKLIRHYSKKGVAGFMPLATTGETPTLSDYEYQSILEKTVECNELNLPIYVGFGGNNTEKMTKDIKMLDKYNIKGILSVCPYYNRPDQRGIYEHFKRISESTSLDIVLYNIPYRTGRNIENDTIRRLSELDNIVGVKDACGDFTQTTELLLNRPDNFSILTGEDAFFYSTLMLGGDGGIMASAHLNTEKYVEVFNKSKQNDYKSALEIWKQVANMIPLLFEEPNPAPIKYCLSKTGVIASEALRLPLVPISENLKEKLNKFL
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase 2, HTPA synthase 2.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSRP_PHOPR
Sequence: MQRKSNFRDVFYVSDGTAITSETLGHAVLGQFPIEIHQTTHPFIETNERAKQVKTLVNQSHEKTGIKPLVFYSIVIPDVKVIIEQSNAHFYDVLNVLVEPLKHDLQLEPEPQLQRSHSINKDAASYQDRIAAIEYTLAHDDGISLNNLDQADVILLGVSRCGKTPTSLYLAMQFGIRAVNYPFIAEDMASLKLPAAIEPYRFKTYGLTIDIERLVAIRNERYANSDYASLEQCEKELHKVEGMFRREAIPYLNTSSLSVEEIATRLLDISGLKRKMC
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: TR2M_AGRRH
Sequence: MAGSSFTLPSTGSAPLDMMLIDDSDLLQLGLQQVFSKRYTETPQSRYKLTRRASPDVSSGEGNVHALAFIYVNAETLQMIKNARSLTEANGVKDLVAIDVPPFRNDFSRALLLQVINLLGNNRNADDDLSHFIAVALPNSARSKILTTAPFEGSLSENFRGFPITREGNVACEVLAYGNNLMPKACSDSFPTVDLLYDYGKFFESCAADGRIGYFPEGVTKPKVAIIGAGFSGLVAASELLHAGVDDVTVYEASDRLGGKLWSHGFKSAPNVIAEMGAMRFPRSESCLFFYLKKHGLDSVGLFPNPGSVDTALFYRGRQYIWKAGEEPPELFRRVHHGWRAFLQDGYLHDGVMLASPLAIVDALNLGHLQQAHGFWQSWLTYFERESFSSGIEKMFLGNHPPGGEQWNSLDDLDLFKALGIGSGGFGPVFESGFIEILRLVVNGYEDNVRLSYEGISELPHRIASQVINGRSIRERTIHVQVEQIDREEDKINIKIKGGKVEVYDRVLVTSGFANIEMRHLLTSSNAFFHADVSHAIGNSHMTGASKLFLLTNEKFWLQHHLPSCILTTGVAKAVYCLDYDPRDPSGKGLVLISYTWEDDSHKLLAVPDKRERFASLQRDIGRAFPDFAKHLTPADGNYDDNIVQHDWLTDPHAGGAFKLNRRGNDVYSERLFFQPFDVMHPADDKGLYLAGCSCSFTGGWVHGAIQTACNATCAIIYGSGHLQELIHWRHLKEGNPLAHAWKRYRYQA
What are the official names of this protein?
Tryptophan 2-monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the tryptophan 2-monooxygenase family.
Protein: GATC_METJA
Sequence: MDEKTIEKIKKEAEEIINKFSEVLEKFNLEMEESYYIIDTRNVLREDEAVESNPEFREKFLKIAPKVNKEGYVVVEKGSWLK
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity).
What are the official names of this protein?
Probable glutamyl-tRNA(Gln) amidotransferase subunit C, Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: CA14A_CONQU
Sequence: SDGRNTAANDKASDLMALRDGCCSNPSCSVNNPDICGGGR
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.
What are the official names of this protein?
Alpha-conotoxin-like Qc1.4a, Qu-5.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL17_SYNS9
Sequence: MRHQCRVPQLGRPADQRKAMLRALTTQLIREGRVTTTKARAKALRDEAERMITLAKDGSLASRRRAIGYIYDKQLVHALFDKAPTRYGERKGGYTRITRTVPRRGDNAEMAIIELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: SECY_AERPE
Sequence: MGVIDVLAAVGERFPAVRKPERKPTLYRRLAWTGVILVLYFIMSNIPLYGIPPQNIGGQVDLQRIIFASSAGTLMELGIGPIVTASLIIQVLVGAKIIKLDLADPEGRRKFTSAQKVLALAFAALEAVAFTVGGRYWVGTAIEPGPLDYALVSLQLFLGALLVIYFDEVMQKGWGIGSAISLFILAGVAQGVVWSIFGTIPGVAQDYGLVPAIISNPDLTLLARPNGFPDLTGFFTTLAAIILLVYLQAMRVEIPITSERFKGIRSRVPLQFIYVTNIPILLVGILVSDLLLVQRLLADYLGVESRAYQIYSSIVYYLSPPRGVVQSIADPVKTAVFIASWTVLSIVFGYMWVEIAGLNPREQAERLIKGGLAIPGMRSDPRVLERVLRRYIYPLTFLSSLIVAALVIVADIFGAYGTGTGLLLAVGIINQYYAMITRERALETYPLLRRILGEEVV
What is the function of this protein?
The central subunit of the protein translocation channel SecYEG.  Consists of two halves formed by TMs 1-5 and 6-10.  These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back.  The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug.  The plug probably moves laterally to allow the channel to open.  The ring and the pore may move independently.
What are the official names of this protein?
Protein translocase subunit SecY, Protein transport protein SEC61 subunit alpha homolog.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RBSA1_BURO1
Sequence: MSRSESPRPLLEMRGISKTFPAVRALDNVSLTVYPGEIHSLMGENGAGKSTLMKILSGAYRADAGGEILIDGQRIEIDGPLAARDAGVAVIYQELCLSPNLTVAENIYVGRELRRGNRRWGTIDRAAMARGCQDVLARLGAPFGPDTLVDTLSIAEQQLVEIARAVHTRARILVMDEPTTPLSSRETEHLFRLIRQLREEGLAIIYISHRMAEIYELSDRVSVLRDGAYVGTLERASLSAERLVAMMVGRDISGFYKKEHAPYDPGHLLLSVRDIADGTRVRGCSLDLHAGEVLGIAGLVGAGRTELARLIFGAEPRVRGDVKLGERTFGAHSPRDAIDAGLVYLTEDRKRQGLFLDMSVRDNINISVCNRDARLGALDLARGAERARDAIASLSIRVPHANVNVGALSGGNQQKVLLSRLLETKPRVLILDEPTRGVDIGAKSEIYRIINELARAGVGVIVISSELPEIIGVADRVLVMREGEIAGELGGHTHTPITQEAIIALATGSQAELADAH
What is the function of this protein?
Part of the ABC transporter complex RbsABC involved in ribose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Ribose import ATP-binding protein RbsA 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
Protein: PCDGL_PANTR
Sequence: MLRKVRSWTEIWRWATLLFLFYHLGYVCGQIRYPVPEESQEGTFVGNVAQDFLLDTDSLSARRLQVAGEVNQRHFRVDLDSGALLIKNPIDREALCGLSASCIVPLEFVTEGPLEMYRAEVEIVDVNDHAPRFPRQQLDLEIGEAAPPGQRFPLEKAQDADVGSNSISSYRLSSNEHFALDVKKRSDGSLVPELLLEKPLDREKQSDYRLVLTAVDGGNPPRSGTAELRVSVLDVNDNAPAFQQSSYRISVLESAPAGMVLIQLNASDPDLGPSGNVTFYFSGHTPDRVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNAPYITVTSELGTLPESAEPGTVVALISVQDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEPRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLDLNDNAPAVLRPRARPGSLCPQALPPSVGAGHLITKVTAVDLDSGYNAWVSYQLLEAPDPSLFAVSRYAGEVRTAVPIPADLPPQKLVIVVKDSGSPPLSTSVTLLVSLEEDTHPVVPDLRESSAPREGESRLTLYLAVSLVAICFVSFGSFVALLSKCLRGAACGVTCFPAGTCACLTRSRRREGLPPSNGILRIQLGSDDPIKFVDVGGHSHGCTPLASAPTRSDSFMMVKSPSAPMAGEPVRPSCPPSDLLYGLEQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.  May be involved in the establishment and maintenance of specific neuronal connections in the brain.
What are the official names of this protein?
Protocadherin gamma-C4, PCDH-gamma-C4.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: NUP98_HUMAN
Sequence: MFNKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKALTTPTHYKLTPRPATRVRPKALQTTGTAKSHLFDGLDDDEPSLANGAFMPKKSIKKLVLKNLNNSNLFSPVNRDSENLASPSEYPENGERFSFLSKPVDENHQQDGDEDSLVSHFYTNPIAKPIPQTPESAGNKHSNSNSVDDTIVALNMRAALRNGLEGSSEETSFHDESLQDDREEIENNSYHMHPAGIILTKVGYYTIPSMDDLAKITNEKGECIVSDFTIGRKGYGSIYFEGDVNLTNLNLDDIVHIRRKEVVVYLDDNQKPPVGEGLNRKAEVTLDGVWPTDKTSRCLIKSPDRLADINYEGRLEAVSRKQGAQFKEYRPETGSWVFKVSHFSKYGLQDSDEEEEEHPSKTSTKKLKTAPLPPASQTTPLQMALNGKPAPPPQSQSPEVEQLGRVVELDSDMVDITQEPVLDTMLEESMPEDQEPVSASTHIASSLGINPHVLQIMKASLLTDEEDVDMALDQRFSRLPSKADTSQEICSPRLPISASHSSKTRSLVGGLLQSKFTSGAFLSPSVSVQECRTPRAASLMNIPSTSSWSVPPPLTSVFTMPSPAPEVPLKTVGTRRQLGLVPREKSVTYGKGKLLMDMALFMGRSFRVGWGPNWTLANSGEQLNGSHELENHQIADSMEFGFLPNPVAVKPLTESPFKVHLEKLSLRQRKPDEDMKLYQTPLELKLKHSTVHVDELCPLIVPNLGVAVIHDYADWVKEASGDLPEAQIVKHWSLTWTLCEALWGHLKELDSQLNEPREYIQILERRRAFSRWLSCTATPQIEEEVSLTQKNSPVEAVFSYLTGKRISEACSLAQQSGDHRLALLLSQFVGSQSVRELLTMQLVDWHQLQADSFIQDERLRIFALLAGKPVWQLSEKKQINVCSQLDWKRSLAIHLWYLLPPTASISRALSMYEEAFQNTSDSDRYACSPLPSYLEGSGCVIAEEQNSQTPLRDVCFHLLKLYSDRHYDLNQLLEPRSITADPLDYRLSWHLWEVLRALNYTHLSAQCEGVLQASYAGQLESEGLWEWAIFVLLHIDNSGIREKAVRELLTRHCQLLETPESWAKETFLTQKLRVPAKWIHEAKAVRAHMESDKHLEALCLFKAEHWNRCHKLIIRHLASDAIINENYDYLKGFLEDLAPPERSSLIQDWETSGLVYLDYIRVIEMLRHIQQVDCSGNDLEQLHIKVTSLCSRIEQIQCYSAKDRLAQSDMAKRVANLLRVVLSLHHPPDRTSDSTPDPQRVPLRLLAPHIGRLPMPEDYAMDELRSLTQSYLRELAVGSL
What is the function of this protein?
(Microbial infection) Interacts with HIV-1 capsid protein P24 and nucleocapsid protein P7 and may thereby promote the integration of the virus in the host nucleus (in vitro) (PubMed:23523133).  Binding affinity to HIV-1 CA-NC complexes bearing the capsid change Asn-74-Asp is reduced (in vitro) (PubMed:23523133).
What are the official names of this protein?
Nuclear pore complex protein Nup98-Nup96.
What is the protein family that this protein belongs to?
Belongs to the nucleoporin GLFG family.
What are the subcellular locations of this protein?
Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Nucleus, nuclear pore complex. Nucleus, nucleoplasm. Note=Localized to the nucleoplasmic side of the nuclear pore complex (NPC), at or near the nucleoplasmic basket (PubMed:11839768). Dissociates from the dissasembled NPC structure early during prophase of mitosis (PubMed:12802065). Colocalized with NUP153 and TPR to the nuclear basket of NPC (PubMed:11839768). Colocalized with DHX9 in diffuse and discrete intranuclear foci (GLFG-body) (PubMed:11839768, PubMed:28221134). SUBCELLULAR LOCATION: Nucleus membrane. Note=(Microbial infection) Remains localized to the nuclear membrane after poliovirus (PV) infection.
Protein: RNH3_STRP7
Sequence: MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVSIYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVATFVTPDQHDFLRKLGVGDSKTLTDQKIRQITPILKEKIQHQALLLSPSKYNEVIGDRYNAVSVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEGKYLSVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLSFCAKLHFKNTEKAKKRLER
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HIII, RNase HIII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family. RnhC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.