PharMolix/UniProtQA huggingface dataset:
Protein: ALT_BPT4
Sequence: MELITELFDEDTTLPITNLYPKKKIPQIFSVHVDDAIEQPGFRLCTYTSGGDTNRDLKMGDKMMHIVPFTLTAKGSIAKLKGLGPSPINYINSVFTVAMQTMRQYKIDACMLRILKSKTAGQARQIQVIADRLIRSRSGGRYVLLKELWDYDKKYAYILIHRKNVSLEDIPGVPEISTELFTKVESKVGDVYINKDTGAQVTKNEAIAASIAQENDKRSDQAVIVKVKISRRAIAQSQSLESSRFETPMFQKFEASAAELNKPADAPLISDSNELTVISTSGFALENALSSVTAGMAFREASIIPEDKESIINAEIKNKALERLRKESITSIKTLETIASIVDDTLEKYKGAWFERNINKHSHLNQDAANELVQNSWNAIKTKIIRRELRGYALTAGWSLHPIVENKDSSKYTPAQKRGIREYVGSGYVDINNALLGLYNPDERTSILTASDIEKAIDNLDSAFKNGERLPKGITLYRSQRMLPSIYEAMVKNRVFYFRNFVSTSLYPNIFGTWMTDSSIGVLPDEKRLSVSIDKTDEGLVNSSDNLVGIGWVITGADKVNVVLPGGSLAPSNEMEVILPRGLMVKVNKITDASYNDGTVKTNNKLIQAEVMTTEELTESVIYDGDHLMETGELVTMTGDIEDRVDFASFVSSNVKQKVESSLGIIASCIDIANMPYKFVQG
What is the function of this protein?
ADP-ribosyltransferase that efficiently ADP-ribosylates one of the two alpha subunits of host RNA polymerase RPOA on an arginine located in the C-terminal region (PubMed:16112649, PubMed:173540).  ADP-ribosylation of RPOA alpha subunit enhances the transcription of viral early genes (PubMed:11021939).  Also ribosylates RPOA subunits beta, beta' and sigma 70 and performs an autoribosylation reaction (PubMed:9193638, PubMed:173540).  Additional in-vitro identified targets include proteins involved in either translation or cellular metabolism such as elongation factor-Tu or GroeL (PubMed:16112649).  Mono-ADP-ribosylates host MAZF which may inactivate the latter (PubMed:26395283).
What are the official names of this protein?
NAD(+)--arginine ADP-ribosyltransferase, Alt protein.
What is the protein family that this protein belongs to?
Belongs to the Tevenvirinae NAD(+)--arginine ADP-ribosyltransferase family.
What are the subcellular locations of this protein?
Virion. Note=About 25- 50 copies per virion. This protein is injected into the bacterial cell along with the viral DNA.
Protein: RL9_PROMH
Sequence: MQIILLDKVANLGSLGDQVNVKSGYARNYLIPQGKAVSATKKNIEFFEARRAELEAKLAETLAAAEARAAKITALGSVTISSKAGDEGKLFGSIGTRDIADAVTAAGVEICKSEVRLPNGVLRTTGDHEVHFQVHSDVFAELNVIIVAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: RL27_RICRO
Sequence: MATKKAGGSSRNGRDSAGRRLGVKKADGQYVIPGNIIVRQRGTKIHPGMNVGLGKDHTIFALIEGRVEFLTKRNHKIVNVKEIAST
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: ROS3_ARATH
Sequence: MEEKSSGGGVRLHVGGLGESVGRDDLLKIFSPMGTVDAVEFVRTKGRSFAYIDFSPSSTNSLTKLFSTYNGCVWKGGRLRLEKAKEHYLARLKREWEAASSTSDNTIKAPSDSPPATHLNIFFPRLRKVKPMPLSGTGKHKYSFQRVPVSSSLPRSFCDCEEHSNSSLTPREIHLHDLEAVNVGRQEAEVNVMNSVMNKLFEKNNVDPEEDNEIEADQDNLIINVASSGNDMDSALDMLSRKRKSILNKKTPSEEGYSEGRKGNLTHPSKNRQTISLEETGRQESSQAIRGKKKPSEVVPDKSSDEPSRTKDLEQSIDNISWSQKSSWKSLMANGNSNDFSVSSFLPGVGSSKAVQPAPRNTDLAGLPSRENLKKKTKRKRVTSTIMAEDLPVSDDIKRDDSDTMADDIERDDSDAVEYYTACESMADDTASDSVAERDDSDAVEDDTAIDSMADDPASDSVAESDDGDAVENDTAIDSMADDTVSNSMAESDDGDNVEDDTAIDSMCDDTANDDVGSDDSGSLADTVSDTSVEAVPLEFVANTEGDSVDGKSNVEKHENVAEDLNAEKESLVVKENVVDEEEAGKGPLKASNKSTGGSSWLQKASWTQLVSDKNTSSFSITQLFPDLTSDKGEAAGVINNVGNQFSNSNQTASAMKQTDYASSSGGFVAAGVPVDSTPVRSLDENRQRLNGKNVSEGAKLGAKKKIIKRKVGSGDTCTFMRSSTSLKEWAKAKKALSEPRRKKNSEE
What is the function of this protein?
RNA-binding protein required for DNA demethylation and to eluviate siRNA-mediated transcriptional gene silencing (TGS), probably by guiding ROS1 (PubMed:18815596).  Can bind specifically single stranded G-rich RNAs of 21-, 24- or 26-nt corresponding to promoter sequence of target genes; this interaction directs demethylation of target sequences (PubMed:18815596).
What are the official names of this protein?
Protein REPRESSOR OF SILENCING 3.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Nucleus, nucleoplasm. Note=Localized in discrete foci dispersed throughout the nucleus.
Protein: ISPH_RUEPO
Sequence: MTKSPLTLYLAAPRGFCAGVDRAIKIVEMAIEKWGAPVYVRHEIVHNKFVVDGLRAKGAVFVEELDECPDDRPVIFSAHGVPKAIPAEAERRQMVYVDATCPLVSKVHIEAERHAEHGLQIIMIGHRGHPETIGTMGQLPEGEVLLVETVADVARIAVRDPARLAFVTQTTLSVDDTRDIVAALQARFPQIVGPHKEDICYATTNRQEAVKAVAPKSDALLVVGAPNSSNSRRLVEVAAKAGCSYAQLVQRADDIDWRALDGIATIAVSAGASAPELLVNEVIDAFRARFDVTVEVVETAVEHVEFKVPRVLRQPA
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: PAX6_BOVIN
Sequence: MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMGTSGATSTGLISPGVSVPVQVPGSEPDMSQYWPRLQ
What is the function of this protein?
Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas.  Required for the differentiation of pancreatic islet alpha cells.  Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters.  Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity).  Acts as a transcriptional repressor of NFATC1-mediated gene expression (By similarity).
What are the official names of this protein?
Paired box protein Pax-6, Oculorhombin.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: URK_SHIFL
Sequence: MTDQSHQCVIIGIAGASASGKSLIASTLYRELREQVGDEHIGVIPEDCYYKDQSHLSMEERVKTNYDHPSAMDHSLLLEHLQALKRGSAIDLPVYSYVEHTRMKETVTVEPKKVIILEGILLLTDARLRDELNFSIFVDTPLDICLMRRIKRDVNERGRSMDSVMAQYQKTVRPMFLQFIEPSKQYADIIVPRGGKNRIAIDILKAKISQFFE
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBF_GNEGN
Sequence: MTTEKIYPIFTVRWLAVHGLAVPTVFFLGSISAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: LEPA_HAES1
Sequence: MKNIRNFSIIAHIDHGKSTLSDRLIQSCGGLSDREMEAQVLDSMDLERERGITIKAQSVTLNYRAKDGETYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAGQGVEAQTLANCYTAIEMDLEVVPILNKIDLPAAEPERVAEEIEDIVGIDAIDAVRCSAKTGVGIEDVLEEIVRKIPAPEGDPNAPLQALIIDSWFDNYLGVVSLVRVKNGILRKGDKIKVMSTGQSYNVDRLGIFTPKQVDTTELKTGEVGWLVCAIKDILGAPVGDTLTSHHNPATSVLPGFKKVKPQVYAGLFPISSDDYESFRDALGKLSLNDASLFYEPENSTALGFGFRCGFLGLLHMEIIQERLEREYDLDLITTAPTVVYEVEQTNGEVIYVDSPAKLPPLNNIAEIREPIAECNMLLPQSYLGNVITLCVEKRGVQTNMVYHGNQVALTYEIPMGEVVLDFFDRLKSTSRGYASLDYGFKRFQAADMVRVDIMINGERVDALALIVHKDNAQYRGRELVEKMRELIPRQQFDIAIQAAIGNHIIARSTVKQLRKNVLAKCYGGDVSRKKKLLQKQKEGKKRMKSLGNVEVPQEAFLAILHVGKDK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DSBB_YERE8
Sequence: MLQFLNRCSKGRGAWLLMALTALVLELVALYFQHVMLLQPCVMCIYERAALFGILGASLLGAIAPKSPLRYLAIFIWIYSAWKGVQLAWTHTMLQLHPSPFTTCDFFVSFPSWLPLDKWFPAVFVASGDCAVKQWEFLSLEMPQWLVGIFAAYLFIAILVLISQFVKPKRRDLFSR
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by oxidizing the DsbA protein.
What are the official names of this protein?
Disulfide bond formation protein B, Disulfide oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the DsbB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS6_BUCA5
Sequence: MRHYEIIFMVHPDQSDKIPLLIEKYKKIINDNNGIIHRLEDWGRRQLSYSINKLQKAHYILMNIEVFPKTITLLETDFRFNNIILRNMIMSVKKAIVELSPILKLKDDKKEKK
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: TPIS_DEBHA
Sequence: MARQFFVGGNFKMNGTRESVSKIVDGLNKAELPSNVEVVIAPPAPYIALAVNENKQKTIEVSAQNCFDKASGAYTGEISPEQIKDLGATWTLTGHSERRTIIKESDDFIASKTKFALDQGLSVILCIGETLEERKANVTLDVCARQLDAVARVVSDWSKIVVAYEPVWAIGTGLAATPEDAQETHKAIREHLSKSIGADAAEKTRILYGGSVNGKNAPEFKDKADVDGFLVGGASLKPEFVDIIKSRL
What are the official names of this protein?
Triosephosphate isomerase, TIM, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
Protein: LPHN_DROME
Sequence: MILSKYQTAYACEGKKLTIECDPGDVINLIRANYGRFSITICNDHGNVEWSVNCMFPKSLSVLNSRCAHKQSCGVLAATSMFGDPCPGTHKYLEAHYQCISAAQTSTTTNRPSPPPWVLSNGPPIFGNGSGLIHPPGVGAGAPPPPRLPTLPGVVGISGNPGLFNVPPQHTAVTHSTPSSSTTAVGGGRLKGGATSTTTTKHPAGRHDGLPPPPQLHHHHNHHGEDTASPTKPSSKLPAGGNATSPSNTRILTGVGGSGTDDGTLLTTKSSPNRPPGTAASGSVVPGNGSVVRTINNINLNAAGMSGGDDESKLFCGPTHARNLYWNMTRVGDVNVQPCPGGAAGIAKWRCVLMKRIPDSGYDEYDDDISSTTPAPSGGDCLHNSSSCEPPVSMAHKVNQRLRNFEPTWHPATPDLTQCRSLWLNNLEMRVNQRDSSLISIANDMSEVTSSKTLYGGDMLVTTKIIQTVSEKMMHDKETFPDQRQREAMIMELLHCVVKTGSNLLDESQLSSWLDLNPEDQMRVATSLLTGLEYNAFLLADTIIRERSVVQKVKNILLSVRVLETKTIQSSVVFPDSDQWPLSSDRIELPRAALIDNSEGGLVRIVFAAFDRLESILKPSYDHFDLKSSRSYVRNTAILSNDSDVNAGEIQQRLRILNSKVISASLGKGRHIQLSQPITLTLKHLKTENVTNPTCVFWNYIDHAWSANGCSLESTNRTHSVCSCNHLTNFAILMDVVDEHQHSLFTMFDGNMRIFIYISIGICVVFIVIALLTLKLFNGVFVKSARTSIYTSIYLCLLAIELLFLLGIEQTETSIFCGFITIFLHCAILSGTAWFCYEAFHSYSTLTSDELLLEVDQTPKVNCYYLLSYGLSLSVVAISLVIDPSTYTQNDYCVLMEANALFYATFVIPVLVFFVAAIGYTFLSWIIMCRKSRTGLKTKEHTRLASVRFDIRCSFVFLLLLSAVWCSAYFYLRGAKMDDDTADVYGYCFICFNTLLGLYIFVFHCIQNEKIRREYRKYVRQHAWLPKCLRCSKTSISSGIVTGNGPTAGTLCSVSTSKKPKLPLGVSEEAHDDPQQQQQTPVPITEDAIMGATSDCELNEAQQRRTLKSGLMTGTLQAPPQTLGGHVVLERGSTLRSTGHASPTSSAGSTHLIFAHKQQQQQQQQGPLGESYYHQPDYYSWKQPSTGTGGLKTPREYYNNAGAAASSPQQAHEVFYWTQKPNSGHNGKKKRGAGGVPASPSGSLHSRTAAASQVLFYPSYKKTKPGQPTGYPQYAEALDPPLATGNAAAYYQQQQQLRRQQLHQQQQQQQQQQLSSDEEQAEQHAHLLHLQRRAGSQQQLPAPPPHMAQYQQEFMQRQYRNKHSNCDLGMGDAYYNQGSVGGADGGPVYEEILSNRNSDVQHYEVGDFDVDEVYNNSVGTGVFNNMRAAVAAGGSRYGGGSLSGGSVSSRSQQQQLKKQQQQQSLAQQRSARRCTADDDDDEDEEEDEEATAAEQLHDSVCDEDEEEDESDLEDDAHGLPPQSDERMRRLMAMQDEDFKRRFQRQLRKHGAPLDYGALPPGAGPQPEHNGAVFGVSGGVGEGSLRGAFRQQQQQALNAKSPGGRLAVNELFGHGNSGPPLPPANQTPAQKRQQLQKLSPQSTTSSSSHTSHSNPNPHPHQLTHPHPHQHPPHHQQRHLSAMLDENNTVRCYLEPLAK
What are the official names of this protein?
Latrophilin Cirl.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y3663_MYCPA
Sequence: MAVTDIFARRATLARSVRLLSQFRYERSEPARFYGALAADTAAMVDDLWRAGHGESAAGRTLLDVGGGPGYFAAAFTDAGVRYLGVEPDPGEMHAAGPVVAADTGTFVRASGMALPFADDSVDICLSSNVAEHVPRPWQLGAEMLRVTRPGGLAVLSYTVWLGPFGGHEMGLTHYLGGARAAERYARKHGHPAKNNYGSSLFEVSVADGLAWAASTGAALAAFPRYHPRWAWSLTSVPVLREFLVSNLVLVLQPQ
What are the official names of this protein?
Uncharacterized methyltransferase MAP_3663c.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: RL21_STAA2
Sequence: MFAIIETGGKQIKVEEGQEIFVEKLDVNEGDTFTFDKVLFVGGDSVKVGAPTVEGATVTATVNKQGRGKKITVFTYKRRKNSKRKKGHRQPYTKLTIDKINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: SRRB_STAAU
Sequence: MMSRLNSVVIKLWLTIILIVTTVLILLSIALITFMQYYFTQETENAIREDARRISSLVEQSHNKEEAIKYSQTLIENPGGLMIINNKHRQSTASLSNIKKQMLNEVVNNDHFDDVFDKGKSVTRNVTIKEKGSSQTYILLGYPTKAQKNSHSKYSGVFIYKDLKSIEDTNNAITIITIITAVIFLTITTVFAFFLSSRITKPLRRLRDQATRVSEGDYSYKPSVTTKDEIGQLSQAFNQMSTEIEEHVDALSTSKNIRDSLINSMVEGVLGINESRQIILSNKMANDIMDNIDEDAKAFLLRQIEDTFKSKQTEMRDLEMNTRFFVVTTSYIDKIEQGGKSGVVVTVRDMTNEHNLDQMKKDFIANVSHELRTPISLLQGYTESIVDGIVTEPDEIKESLAIVLDESKRLNRLVNELLNVARMDAEGLSVNKEVQPIAALLDKMKIKYRQQADDLGLNMTFNYCKKRVWSYDMDRMDQVLTNLIDNASRYTKPGDEIAITCDENESEDILYIKDTGTGIAPEHLQQVFDRFYKVDAARTRGKQGTGLGLFICKMIIEEHGGSIDVKSELGKGTTFIIKLPKPE
What is the function of this protein?
Member of the two-component regulatory system SrrA/SrrB, which is involved in the global regulation of staphylococcal virulence factors in response to environmental oxygen levels as well as biofilm formation.  Also plays an essential role in host-derived nitric oxide resistance by regulating hmp/flavohemoglobin, an enzyme that detoxifies nitric oxide by converting it to nitrate.  Functions as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to SrrA.  In turn, SrrA binds to the upstream promoter regions of the target genes to positively and negatively regulate their expression.
What are the official names of this protein?
Sensor protein SrrB, Staphylococcal respiratory response protein B.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FUCDH_XANCP
Sequence: MAADRTAAGTAVRRRQCRGGVRRQRTHVLSSATAGGPHPRNLIGMTVSIPTTPNTRLQGKRCLITAAGAGIGRESALACARAGAHVIATDIDAAALQALAAESDAITTQLLDVTDAAAITALVAAHGPFDVLFNCAGYVHQGSILDCDEPAWRRSFSINVDAMYYTCKAVLPGMLERGRGSIINMSSVASSIKGVPNRFVYGVTKAAVIGLSKAIAADYVAQGVRCNAICPGTIKTPSLGQRVQALGGDEQAVWKSFTDRQPMGRLGDPREIAQLVVYLASDESSFTTGQTHIIDGGWSN
What is the function of this protein?
Plays a role in the catabolism of L-fucose.  Catalyzes the NAD(+)-dependent oxidation of 2-keo-3-deoxy-L-fuconate to 2,4-diketo-3-deoxy-L-fuconate.
What are the official names of this protein?
2-keto-3-deoxy-L-fuconate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: RS12_BACAA
Sequence: MPTINQLVRNGRTDKVWKSKSPALNKGFNSLKKKSTDISAPQKRGVCTRVGTMTPKKPNSALRKYARVRLTNGIEVTAYIPGIGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGALDTAGVDKRMQGRSKYGTKKPKAAKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RS11_HERAR
Sequence: MAKAPNNAAAARVRKKVKKNVAEGIAHIHASFNNTIITITDRQGNALSWATSGGAGFKGSRKSTPFAAQVAAEAAGKVAIECGIKNLEVRIKGPGPGRESSVRALNNLGIKITQIQDVTPVPHNGCRPPKRRRI
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: NSP3_ROTHP
Sequence: MESTQQMVSSIINTSFEAAVVAATSTLELMGIQYDYNEVFTRVKSKFDYVMDDSGVKNNLLGKAITIDQALNGKFGSAIRNRNWMTDSKTVAKLDEDVNKLRMTLSSKGIDQKMRVLNACFSVKRIPGKSSSIIKCTRLMKDKIERGEVEVDDSYVDEKMEIDTIDWKSRYDQLEKRFESLKQRVSEKYNTWVQKAKKVNENMYSLQNVISQQQNQIADLQQYCNKLEADLQGKFSSLVSSVEWYLRSMELSDDVKNDIEQQLNSIDLINPINAIDDIESLIRNLIQDYDRTFLMLKGLLKQCNYEYAYE
What is the function of this protein?
Plays an important role in stimulating the translation of viral mRNAs.  These mRNAs are capped but not polyadenylated, instead terminating in a conserved sequence 'GACC' at the 3' that is recognized by NSP3, which competes with host PABPC1 for EIF4G1 binding.  The interaction between NSP3 and host EIF4G1 stabilizes the EIF4E-EIF4G1 interaction, thereby facilitating the initiation of capped mRNA translation.
What are the official names of this protein?
Non-structural protein 3, NSP3, NCVP4, Non-structural RNA-binding protein 34, NS34.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP3 family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: Y2464_STAAS
Sequence: MRKDAKENRQRIEEIAHKLFDEEGVENISMNRIAKELGIGMGTLYRHFKDKSDLCYYVIQRDLDIFITHFKQIKDDYHSNYEVMQVSLDYLLQFKIDNKALLQCIEAGNNKLRFYQSAFYQELFDFYYDLFKSDDDTYTKFKTDMLLQSLSTSVFAFQIEHRHISIEAYRNYLLNIYLDEVERND
What are the official names of this protein?
HTH-type transcriptional regulator SAS2464.
Protein: S2611_MOUSE
Sequence: MAPDTCCCSATALRRRLPVLAWVPDYSLQWLRLDFIAGLSVGLTVIPQALAYAEVAGLPPQYGLYSAFMGCFVYFFLGTSRDVTLGPTAIMSLLVSFYTFREPAYAVLLAFLSGCIQLAMGLLHLGFLLDFISCPVIKGFTSAASITIGFGQIKNLLGLQKIPRQFFLQVYHTFLHIGETRVGDAVLGLASMLLLLVLKCMREHMPPPHPEMPLAVKFSRGLVWTVTTARNALVVSSAALIAYAFEVTGSHPFVLTGKIAEGLPPVRIPPFSVTRDNKTISFSEMVQDMGAGLAVVPLMGLLESIAVAKSFASQNNYRIDANQELLAIGLTNVLGSLVSSYPVTGSFGRTAVNAQTGVCTPAGGLVTGALVLLSLNYLTSLFSYIPKSALAAVIITAVTPLFDVKIFRSLWRVQRLDLLPLCVTFLLSFWEIQYGILAGSLVSLLILLHSVARPKTQVSEGQIFVLQPASGLYFPAIDALREAITNRALEASPPRSAVLECTHISSVDYTVIVGLGELLEDFQKKGVALAFVGLQVPVLRTLLAADLKGFRYFTTLEEAEKFLQQEPGTEPNSIHEDAVPEQRSSLLKSPSGP
What is the function of this protein?
Exhibits sodium-independent sulfate anion transporter activity that may cooperate with SLC26A2 to mediate DIDS-sensitive sulfate uptake into high endothelial venules endothelial cells (HEVEC).
What are the official names of this protein?
Sodium-independent sulfate anion transporter, Solute carrier family 26 member 11.
What is the protein family that this protein belongs to?
Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein.
Protein: VATA_PARUW
Sequence: MKTLETRKEKKAQGKVLKAFGNLLQVTFEGNIRQGEVAMVHVDNLQLKSEVIEILGNQAKIQVFEDTKGVRLGSLVSFTGDLLEAELGPGLLSSIFDGLQNPLVDVADQAGLFLPKGIYLSALDRQRKWDFESSAKVGDVLFRGDRIGSTKEGRFHHFIMVPFSLYGKYRLTWVINSGSYTVDTVVAKAIDESGQEHSFTMVQKWPVKNALIHGEKIKPTKMMDTGERIIDTQFPLMKGGTFCTPGPFGAGKTVLQHHLSKYAAVDIVLFVACGERAGEVVEVLREFPHLIDPHTDEALMKRTVIICNTSSMPVAARESSIYMGITIAEYYRQMGLDVLVLADSTSRWAQALREMSGRLEEIPGEEAFPAYLSSRIAEFYERSGVVSLRHGKPGSITIGGAVSPAGGNFEEPVTQATLSVVGAFLGLSRARSDSRRYPAIDPLLSWSKYVDTVGNELSHQVDGWDQMVKRARHILFNGNEIGKRMEVVGEEGISMEDMLTYLKAELYDFSYLQQNAFDKEDAYCPLKRQIALFQLINQIFDTTFDFHTHDQAREFFLDLQNRIKNMNFISFDTEQYRKVFAEIKSIIEQQSRK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type alpha chain is a catalytic subunit.
What are the official names of this protein?
V-type ATP synthase alpha chain, V-ATPase subunit A.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: RIR1_CRYPV
Sequence: MYVVNRKGEEEPVSFDQILSRITKLSYGLHPLVDPARVTQAVINGLYSGIKTSELDELASQTCAYMAATHNDFSKLAARISTSNLHKNTSSDIGDVASQLYNFKDNQGCPAPLISKPVYDFIMENRERINSKIDFSKDFEYDYFAFKTLERSYLLKIDNKVVERPQHLLMRVSCGIHCGDIEAALETYELLSQKYFTHATPTLFNSGTPRPQMSSCFLLRIPEDSINGIFDTLTKCANISKTAGGLGVAVSNIRGTGSYIRGTNGRSNGLIPMLRVYNDTARYIDQGGGKRKGAIAIYLEPWHVDVVEFIEIRKNHGKEEMRCRDLFPALWVPDLFMERVEKDQDWTLMCPDECRGLQDVWGDDFKKLYEEYEKQGRGRKTMKAQKLWFLILQAQIETGTPFICYKDAANSKSNQKNLGTIVSSNLCTEIIEYTSTDEVAVCNLASIGLPKFVDKNNKTFDFDKLKEVTKVITRNLNKLIDVGYYSLKECKKSNLRHRPLGIGIQGLADCFMMLRMPYESEGAKKLNKQIFEVIYYAALDASCELAEKYGPYETYSGSPASKGILQFDMWGVTPDSGLCDWDLLKDRISKHGIRNSLLISPMPTASTSQILGNNESFEPFTSNIYHRRVLSGEFFVVNPHLLNDLLELGLWDDRLKQNIIANNGSIQNILTIPEDIRELYKTVWEIKQKTVIDMAADRGPYVCQSQSLNIHMENANFAKLSSMHFYGWKKGLKTGIYYLRTQSATRPIQFTVDQQLLKSETKEKDSLETNKRQALEPEAQKLIACPLRPTNMKDDEECMMCSG
What is the function of this protein?
Provides the precursors necessary for DNA synthesis.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
What are the official names of this protein?
Ribonucleoside-diphosphate reductase large chain, Ribonucleotide reductase R1 subunit.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase large chain family.
Protein: DDH_ZYMMO
Sequence: MRVAIFSSKNYDHHSIEKENEHYGHDLVFLNERLTKETAEKAKDAEAVCIFVNDEANAEVLEILAGLGIKLVALRCAGYNNVDLDAAKKLNIKVVRVPAYSPYSVAEYAVGMLLTLNRQISRGLKRVRENNFSLEGLIGLDVHDKTVGIIGVGHIGSVFAHIMTHGFGANVIAYKPHPDPELAKKVGFRFTSLDEVIETSDIISLHCPLTPENHHMINEETLARAKKGFYLVNTSRGGLVDTKAVIKSLKAKHLGGYAADVYEEEGPLFFENHADDIIEDDILERLIAFPNVVFTGHQAFLTKEALSNIAHSILQDISDAEAGKEMPDALV
What are the official names of this protein?
2-hydroxyacid dehydrogenase homolog.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
Protein: ORF1_SPV1C
Sequence: MRKSLSLFSIFILIFLGLVIPFITLTAFRPLNEEQYTLKQESSTGKGINETDFINTMFLRSSFFENWSETNYFINPTLKTSKNLLFNDKWYLDFLQDSYSTGVVYDKPNEVFLNYYQQWHSLKNRYMVEKFYDVKKENFLNDLIDFIYAFAVKYKMFNVSKEIVKNVDRYKENHYPRVKLNQDNWKLIDDIENVDKYKWEDETYIGITKIWKNKEWNWIIEDWKLHPPFSNVYLSSYKAIYRWTGVGKPQLPTIDKNTGEITDWNSYQQTRVKEFIDLSLYSVLLENTRVQQGGSADYENPNKVGTKRIIFDFETVDELDVKNIKKAIYRMILTVDEANLIISGSLELNNINNDDLSFNFSFMRTGMGEVFNFNGSIYSSLNSKDLKYYQQFSGQFDLSKFLQSFFASALVPVFQNRSSFIENGYIDNLQYDTVLVNFFALKLQNFNNILLSENINDKLQFDKLLNSMFKISQKFYTNYLRTIFDLENNTYVQGYNKKYGLLVNNGFKIYPRYFYFSDKYKQLDIKLYSAFKNRFYTINNYGSVFNYDFSVANNYNISLNSGYVFGGDLQNKYGLQYKKIEEQKIGYNVFELQAQKENDMYRYYDFNFGIYNWQEINNGGLFPDKQWWQVQYITPKGWWDFGAHIKNAVIWIVNTIPGVKQVNELASGVGKVFETVYSFFSQIFEVWKFNPALYSTITNIFLLIIFMKFVRLI
What are the official names of this protein?
Uncharacterized protein ORF1.
What is the protein family that this protein belongs to?
Belongs to the plectrovirus ORF1 family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: HYPA_STRAW
Sequence: MHEMSVALAVIDQVEQAAQQAGDVTAVRSVRLQVGELAGVVPDSLSFCFELACAGTVLEGADLVTEEVPGRARCAPCAREWSVGMPPRLSCPECGGARVDLLSGRELQIVSVHWEDGRTHAQTREPISEER
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.