PharMolix/UniProtQA huggingface dataset:
Protein: PA2A2_ASPSC
Sequence: NLYQFKNMIQCTVPNRSWWHFADYGCFCGYGGSGTPVDELDRCCQTHDNCYSEAEKLSGCKPYIKTYSYDCSQGKLTCSGNDDKCAAFVCNCDRVAAICFAGAPYIDDNYNVDLNERCQ
What is the function of this protein?
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Acidic phospholipase A2 CM-II, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PTH_STRPF
Sequence: MVKMIVGLGNPGSKYEKTKHNIGFMAIDNIVKNLDVTFTDDKNFKAQIGSTFINHEKVYFVKPTTFMNNSGIAVKALLTYYNIDITDLIVIYDDLDMEVSKLRLRSKGSAGGHNGIKSIIAHIGTQEFNRIKVGIGRPLKGMTVISHVMGQFNTEDNIAISLTLDRVVNAVKFYLQENDFEKTMQKFNG
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LYRM9_XENTR
Sequence: MPPLPGAELVHNPLQLYRYLLRCCKLLPTESLQHYYRHSVKQSFRVHADEDDPERIQQIIKRAIEDADWVLNKYKKES
What are the official names of this protein?
LYR motif-containing protein 9.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family. LYRM9 subfamily.
Protein: GRM7_MOUSE
Sequence: MVQLGKLLRVLTLMKFPCCVLEVLLCVLAAAARGQEMYAPHSIRIEGDVTLGGLFPVHAKGPSGVPCGDIKRENGIHRLEAMLYALDQINSDPNLLPNVTLGARILDTCSRDTYALEQSLTFVQALIQKDTSDVRCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYASTAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYGEKGVESFTQISKEAGGLCIAQSVRIPQERKDRTIDFDRIIKQLLDTPNSRAVVIFANDEDIKQILAAAKRADQVGHFLWVGSDSWGSKINPLHQHEDIAEGAITIQPKRATVEGFDAYFTSRTLENNRRNVWFAEYWEENFNCKLTISGSKKEDTDRKCTGQERIGKDSNYEQEGKVQFVIDAVYAMAHALHHMNKDLCADYRGVCPEMEQAGGKKLLKYIRNVNFNGSAGTPVMFNKNGDAPGRYDIFQYQTTNTTNPGYRLIGQWTDELQLNIEDMQWGKGVREIPPSVCTLPCKPGQRKKTQKGTPCCWTCEPCDGYQYQFDEMTCQHCPYDQRPNENRTGCQNIPIIKLEWHSPWAVIPVFLAMLGIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKPDVAVCSFRRVFLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSLISVQLLGVFIWFGVDPPNIIIDYDEHKTMNPEQARGVLKCDITDLQIICSLGYSILLMVTCTVYAIKTRGVPENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEKLYIQTTTLTISMNLSASVALGMLYMPKVYIIIFHPELNVQKRKRSFKAVVTAATMSSRLSHKPSDRPNGEAKTELCENVDPNSPAAKKKYVSYNNLVI
What is the function of this protein?
G-protein coupled receptor activated by glutamate that regulates axon outgrowth through the MAPK-cAMP-PKA signaling pathway during neuronal development (By similarity).  Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase that it inhibits (By similarity).
What are the official names of this protein?
Metabotropic glutamate receptor 7, mGluR7.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KPRS_MYCBO
Sequence: MSHDWTDNRKNLMLFAGRAHPELAEQVAKELDVHVTSQDAREFANGEIFVRFHESVRGCDAFVLQSCPAPVNRWLMEQLIMIDALKRGSAKRITAVMPFYPYARQDKKHRGREPISARLIADLLKTAGADRIVTVDLHTDQIQGFFDGPVDHMRGQNLLTGYIRDNYPDGNMVVVSPDSGRVRIAEKWADALGGVPLAFIHKTRDPRVPNQVVSNRVVGDVAGRTCVLIDDMIDTGGTIAGAVALLHNDGAGDVIIAATHGVLSDPAAQRLASCGAREVIVTNTLPIGEDKRFPQLTVLSIAPLLASTIRAVFENGSVTGLFDGDA
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase, RPPK, 5-phospho-D-ribosyl alpha-1-diphosphate synthase, Phosphoribosyl diphosphate synthase, Phosphoribosyl pyrophosphate synthase, P-Rib-PP synthase, PRPP synthase, PRPPase.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_NATPD
Sequence: MSDRNIRVEPVVGRAVEEQDVEIVERKGLGHPDSLCDGIAEHVSQALARAYIDRVGKVLHYNTDETQLVAGTAAPAFGGGEVVDPIYLLITGRATKEYEGTKIPAETIALRAAREYINETLPFLEFGTDVVVDVKLGEGSGDLQEVFGEDGKQVPMSNDTSFGVGHAPLTETERIVLEAERALNGDYSDDNPAVGQDIKVMGKREGDDIDVTVAVAMVDRYVDDLDGYEAAVAGVREFVADLATDYTDRNVSVHVNTADDYDEGAIYLTTTGTSAEQGDDGSVGRGNRSNGLITPNRSMSMEATSGKNPVNHIGKIYNLLSTEIARTVVDEVDGIREIRIRLLSQIGQPIDKPHVADANLVTEDGIEIADIEDEVEAIIDAELENVTSITERVIDGELTTF
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase 2 family.
Protein: OBG_JANMA
Sequence: MKFIDEAKIEVIAGDGGNGVASFCREKFRPFGGPDGGDGGKGGSIYAVADRNINTLVDFRFAKMHKAKNGENGRGADCYGKGADDIKLRMPVGTLIIDNNDGELIADLTEHGQEVLIAKGGEGGWGNIHFKSSTNRAPRQKSEGKEGERRELRLELKVLADIGLLGMPNAGKSTFISAVSNARPKIADYPFTTLHPNLGVVRVSHEKSFVIADIPGLIEGASDGAGLGIQFLRHLQRTRLLLHIVDLAPFDNVDPVKEAKAIVKELKKYDEALFDKPRWLVLNKLDMVPEEERKKRVKDFIKRFGWKGPVFEISALTREGCSDLVTEIYEYIAVQRQAEQRTEETPQMVEEARGIDSIDPDDPRFKIID
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YKT6_RAT
Sequence: MKLYSLSVFYKGEPKAVLLKAAYDVSSFSFFQRSSVQEFMTFTSQLIVERSAKGSRASVKEQEYLCHVYVRSDSLAGVVIADSEYPSRVAFTLLEKVLDEFSKQVDRIDWPVGSPATIHYTALDGHLSRYQNPREADPMSKVQAELDETKIILHNTMESLLERGEKLDDLVSKSEVLGTQSKAFYKTARKQNSCCAIM
What is the function of this protein?
Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment.  Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5.  Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5.  Has a S-palmitoyl transferase activity.
What are the official names of this protein?
Synaptobrevin homolog YKT6.
What is the protein family that this protein belongs to?
Belongs to the synaptobrevin family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasmic vesicle membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side. Note=Probably cycles through vesicles between Golgi and endosomes.
Protein: CHER1_VIBCH
Sequence: MTAITISDQEYRDFCRFLESQCGIVLGDSKQYLVRSRLSPLVTKFKLSSLSDLLRDVVTGRNRDLRVAAVDAMTTNETLWFRDSYPFTVLADKLLPEMAANKRPIKIWSAASSSGQEPYSMAMTILEVQQKRPGLLPSVSITATDISASMLDMCRAGIYDNLALGRGLSPERRRVFFEDAGDGRMKVKDNVKRLVNFRPQNLMESYSLLGKFDIIFCRNVLIYFSPDMKSKVLNQMAASLNPGGYLLLGASESLTGLTDKFEMVRCNPGIIYKLK
What is the function of this protein?
Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
What are the official names of this protein?
Chemotaxis protein methyltransferase 1.
Protein: CCA_VIBC1
Sequence: MQVYLVGGAVRDHLLGIDIYDRDWVVVGATPEIMLSQGYTAVGKDFPVFLHPKTKEEHALARTERKSGAGYTGFECFFDQSVTLEEDLIRRDLTINAMAMDEDGNLYDPYGGQKDIDAKVLRHVSQAFVEDPLRVLRVARFAAKLAHLGFSVAEETMQLMRDMAESGELSTLTPERVWQEWHKSLSTSRPDVFLSVLRDCGALAVVLPEIDALFGVPQPEKWHPEIDTGIHTLMVAQQAAKLSDSLPVRFAAQVHDLGKGVTPESEWPSHKMHCHTGLKLIKKLCDRVRVPNEFRDLALMVCEQHSNIHRAAELKPQTIIKILNKFDVWRKAERLQDILICCQADHAGRKGLEDQPYPQAELFMRAYQAAASVDVQAIIKDGFKGPAIRDEQEKRRAEAVKVALGK
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: COX2_APILI
Sequence: MSTWFMFMFQESNSYYADNLISFHNMVMMIIIMISTLTVYIILDLFMNKFSNLFLLKNHNIEIIWTIIPIIILLIICFPSLKILYLIDEIVNPFFSIKSIGHQWYWSYEYPEFNNIEFDSYMLNYNNLNQFRLLETDNRMVIPMKIPLRLITTSTDVIHSWTVPSLGIKVDAVPGRINQLNLISKRPGIFFGQCSEICGMNHSFMPIMIESTSFQYFLNWVNKQI
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SLX1_BOTFB
Sequence: MLRQQMPIDRPIPSFYGCYLLRSTIRHSALYVGSTPNPVRRLRQHNGLVKGGAVRTSRGNLRPWEMACIVTGFPTSIAALQFDRWAWQNPHITLHIPPSSRISHATQKKRSGHPKRPRHTLQSLLSNLHILLTVPSFSRWPLEIKFFAPDVHRAWLKWSKAATGSLRDTLPIITDFPPAESQVNDEDGEITDRPYGIEALNVAYEDTKSHLEKGERIFHSEMKESCNICNQDLQHNSGLYTICPNINCHSITHMTCLSQHFLRAEKNEQSGEELIPVQGMCPGCRMDIRWNDVVKELSLRMRGQKVVEKLLGAKRVKKGKGIATSQEVVESEGDEEEEEEEEKEQELVDYFDADEFHARNVAQEENGFVDYLDDDDSDAVSNISMESSKSPKRKRTIGPFSKAKLIAVIEDSDVDEEIEGEELER
What is the function of this protein?
Catalytic subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination.  Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
What are the official names of this protein?
Structure-specific endonuclease subunit slx1.
What is the protein family that this protein belongs to?
Belongs to the SLX1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y755_PROMM
Sequence: MLIESMGLACFARPLQWFKSQWLWLLLSIAAFCLLMRVQVEWLWFGQFDWQGMLLRRWLWQLGGLLLALLVVATCQLWQRNWIKLEVASNLGESSLSLHGWRYGLGLLGCFVVVVGDLVLLSRLAWLACFKPFDLGHWWSEPFEDIWALVIPLSCVFISICVMLGNARGGRIAHLIGCFCFSISIARGWGLWALALAIPPTGIKEPLLGGDVSFGLGQFPALAFALVVLLAQLILTTCTTIWMKLAQPESLSDWVFKGLSPRQCNFLRPLIGIILLTLSALLWLSRHELLWTQNGTVAGAGWLDAHLILPLRSLASLAILVFAFLVIPFTWIQQRRLLRLIASIIGVGAILLEVLLAPFVQWMVVKPRELKLETPYIIRAIKATRKAFQLDSITTTLINPQPQLTQLDLEQGASTLRNIRLWDSQPLLATNRQLQQLRVYYRFSNAAVDRYRFVPDVANRQQVMITARELDQAALPKRSRTWLNRHFVFTHGYGFTLSPVNTRAPDGLPDYFISDLGTSTRLEGSSELGITREDVKEAVPIGRAALYFGMLPSPYALAPSKLKELDYPVGDKNIYNHYLGSGGVPVGQPWQQLAAAMYLFEPRLLNTGSLTINSKLLIRREVRQRVRAIAPFLEVIGDPYLVSTSVSSKDLNYEAKQNQYWIVEAYTSSRTYPYAANLPDGRPLRYLRNSVKAIVDAYSGRVHLYVSEPRDPIILGWQRLFPDLFKPLEEMPSSLREHLKVPTDLFNVQVQQLLRYHVTDPRIFYSGDDVWQVPKELYGRRQVPVDPYHITAQLGTQESSEFLLLQPLTPLARPNLSAWLAARSDGEHYGKLVLLRFPSQTPIFGPEQIQALINQDPQISQQFGLWDRAGSEVVQGNLLVVPLGKALLYVEPVYLRARQGGLPTLTRVVVSDGKRIAMAEDLGEGLRALVDGSSNKAVYLNRNDLPPIKAADQLN
What are the official names of this protein?
UPF0182 protein PMT_0755.
What is the protein family that this protein belongs to?
Belongs to the UPF0182 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GPMA_STRA1
Sequence: MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIQAAGIEFDLAFTSVLKRAIKTTNLALEAADQLWVPVEKSWRLNERHYGGLTGKNKAEAAEQFGDEQVHIWRRSYDVLPPDMAKDDEHSAHTDRRYASLDDSVIPDAENLKVTLERALPFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKQLSDDEIMDVEIPNFPPLVFEFDEKLNLVSEYYLGK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: THYX_THET2
Sequence: MEGPLTIPVLDKGFVRLVDQMGDDRAIVQAARVSYGEGTKTVREDAALIDYLMRHRHTSPFEMVVFKFHVKAPIFVARQWFRHRTASVNEISGRYSILKEEFYEPEAFRKQAKRNKQASEGALLDEEALALLRKVEQEAYGAYRALLEKGVAREMARMVLPLNLYTEFYWKQDLHNLFHFLKLRLAPEAQWEIRQYARAIAEIVKERVPLAWAAFEEHLLEGAFLSRTELRALRGLLTPEVYEKALSSLGLGGSRLKEALEKVFGPGEAL
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
What are the official names of this protein?
Flavin-dependent thymidylate synthase, FDTS, FAD-dependent thymidylate synthase, Thymidylate synthase ThyX, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase ThyX family.
Protein: VTU3_DROME
Sequence: MKCIAIVSTICLLAAFVAADKEDKMLGSSYGGGYGKPAAAPAPSYSAPAAAPQAYAAPAAPSYAAAPVSIPAPPCPKNYLFSCQPNLAPVPCSAPAPSYGSAGAYSQYAPVYAPQPIQW
What is the function of this protein?
Major early eggshell protein.
What are the official names of this protein?
Vitelline membrane protein Vm34Ca.
What is the protein family that this protein belongs to?
Belongs to the vitelline membrane protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: SRA31_CAEEL
Sequence: MEIPGKCTSEEIRLTLTSSFMMGNHCFILLIIISSVFLTVFAIRKLWKNNIFPNCTRTLLFSAIINGVVHHWSIAGIRIRTVYRALVYGSDRCSILFQSSECLIESNLYYYTNLFSSLCCISLFFDRLLSLNAKTSYNTKHFSKIFLLFQSISPFGILYWIFYDSVYTGFVPMCSYPPATSSLKFHKVNEFRLYILGTFFVLSFVIFFYNRTQEKGIIHNVYDTESRYKSYENLLATRAVCIIIATQITCLVTTASTTEILSAYKSSIPNTILLPSIAFMTGLTYSNFFLPIIIIYQTNRIINQRYNAIKRIQNEKSFATHFASLDLSWKSSKIDNSS
What are the official names of this protein?
Serpentine receptor class alpha-31, Protein sra-31.
What is the protein family that this protein belongs to?
Belongs to the nematode receptor-like protein sra family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: VE4_HPV54
Sequence: MADNQVPKRHCQYPLLALLNTPDQPIPHHVPTTPQKQSRARRRLENELESTAQTSNHTAPQTPWAVTTTGTSVTITTRTKDGTQVVVTLHL
What is the function of this protein?
Contributes to multiple aspects of the viral life cycle including viral genome amplification, suppression of suprabasal cell differentiation and egress of newly formed virions.  Induces host cell cycle arrest at the G2 phase by associating with and preventing the nuclear entry of host CDK1/cyclin B1 complexes.  Inhibits cellular DNA replication by preventing loading of host replication licensing proteins MCM2 and MCM7 onto chromatin.  Within the cytoplasm, associates with host kinase SRPK1, a splicing factor regulator, and inhibits its activity.  Therefore, E4 favors expression of late viral transcripts by inhibiting SRPK1-mediated phosphorylation of host serine-arginine (SR) proteins that have critical roles in mRNA metabolism.  Late in the infectious cycle, E4 also acts to diminish the integrity of the keratinocyte by disrupting the keratin cytoskeleton and inducing apoptosis through alteration of mitochondrial function to facilitate egress of the newly formed virions.
What are the official names of this protein?
Protein E4.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E4 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: SYVC_TAKRU
Sequence: MATLYVSPHLDDFRSLLALVAAEYCGNAKQQSQVWQWLSFADNELTPVSCAVVFPLMGMTGLDKKIQQNSRVELMRVLKVLDQALEPRTFLVGESITLADMAVAMAVLLPFKYVLEPSDRNVLMNVTRWFTTCINQPEFLKVLGKISLCEKMVPVTAKTSTEEAAAVHPDAAALNGPPKTEAQLKKEAKKREKLEKFQQKKEMEAKKKMQPVAEKKAKPEKRELGVITYDIPTPSGEKKDVVSPLPDSYSPQYVEAAWYPWWEKQGFFKPEFGRKSIGEQNPRGIFMMCIPPPNVTGSLHLGHALTNAIQDTLTRWHRMRGETTLWNPGCDHAGIATQVVVEKKLMREKGTSRHDLGREKFIEEVWKWKNEKGDRIYHQLKKLGSSLDWDRACFTMDPKLSYAVQEAFIRMHDEGVIYRSKRLVNWSCSLNSAISDIEVDKNELSGRTLLPVPGYKEKVEFGVLVSFAYKVDGSDEEVVVATTRIETMLGDTAVAVHPSDSRYQHLKGKTVLHPFCDRKIPVVFDDFVDMSFGTGAVKITPAHDHNDYEVGVRHNLAFINILDENGFVINVPPPFLGMKRFDARKAVLQALKDRDQFKEIKDNPMVVPVCSRSKDIVEPLMKPQWYVSCSDMGKQAADAVREGRLKIIPDHHSQTWFNWMDNIRDWCISRQLWWGHRIPAYFITVSDPSVKPGEDMDGHYRVSGRTPEEAREKAAKRFNVSPDKIALRQDEDVLDTWFSSGINPFSILGWPNETEDLNVFYPGTLLETGHDILFFWVARMVMMGLKLTGKLPFKEVYHCAVVRDAHGRKMSKSLGNVIDPLDDHIGIALEGLHAQLMDTNLDPLEVEKPKKVQKADYPNCIPECGTDALRFALCAYTSQGRDINLDVNRILGYRHFCNKLWNAVKFAMRTLGDQFVPADTSPAEREESVSDRWILSRLSTAVAQCDAAFRTYDFPAITTAIYNFWLYELCDVYLESVKPVFIKAKEDGSCERPAAVCRQTLYTCLEVGLRLLAPLMPFVTEELYQRLPRRRPQSDPPSICVTPYPDAAEFCWQCEDVDRDIDFIMGVVRTIRSLRSDYKLTKTAADCYLQCTDAATVSLVQKYSLQIQTLSYSQAIVPLMAPQPAPEGCAVAIASDRCTVNMMLKGLIDVEKEVPKLMGKKTDLEKQIEKLSEKISKGDYKEKVPVKVQEQDTEKLRQSQTELEKVKEAMDNFQKMM
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
Protein: HUB1_DEBHA
Sequence: MIEVLANDRLGKKIKVKCMPTDTIGDLKKIISLQIGTSYEKIVLKKGYQVYKDHITLDDYEVHNGFNFELYYS
What are the official names of this protein?
Ubiquitin-like modifier HUB1.
Protein: METN3_BACCR
Sequence: MILLENVKKIYKAKSGDVTAVDNANLKIEKGEIFGVIGYSGAGKSSLIRLFNQLEKPTSGQITIANRVISAITGSELRKARQEIGMIFQHFNLLWSRTVRENIEFPLEIAGVDKAKRRKRVDELIHLVGLEGRGDAYPSQLSGGQKQRVGIARALANNPQVLLCDEATSALDPETTDQILDLLLDINKRLGLTIVLITHEMHVIRKICNRVAVMEKGKIVETGPVLDVFRNPKQDITKRFVQQLTDSEDTNETIESLIEKYPDGKVIRLQFIGEAVERPVLQRLMQRSDIEVSILQGNIAQTNNGSYGSLVVHLNGEETAIQQAIEGIHQDQVELEVIAHG
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN 3.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TBB_ENCCU
Sequence: MREIIHLQTGQCGNQVGCKFWETISGEHGIDQTGRYVGTSDNQLERINVYYNEASSKKYVPRAVLIDLEPGTMDAVRQGPFGELFRPDNFVFGQSGAGNNWAKGHYTEGAELIDSVMDVVRKEAESSDCLQGFQITHSLGGGTGAGMGTLLLSKIREDFPDRMICTFSVVPSPKVSDTVVEPYNATLSIHQLVENADETFCIDNEALYDICFRTLKLNNPGYGDLNHLVSLVMSGVTTCLRFPGQLNADLRKLAVNMIPFPRLHFFVAGFAPLIAIGTQKFKTYSVSELTQQMFDSKNMMTACDPRKGRYLTVAAMFRGKISMKDVDEQMSMVQSKNSSLFVEWIPSNVKTAVCDIAPTGLEMSATFVGNTTSIQELFKRISDQFTVMFRRKAFLHWYTGEGMDEMEFSEAESNMNDLLSEYQQYQDATIEDAEEFLVN
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta chain, Beta-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: GSHR_PSEAE
Sequence: MSFDFDLFVIGAGSGGVRAARFAAGFGARVAVAESRYLGGTCVNVGCVPKKLLVYGAHFSEDFEQARAYGWSAGEAQFDWATLIGNKNREIQRLNGIYRNLLVNSGVTLLEGHARLLDAHSVEVDGQRFSAKHILVATGGWPQVPDIPGKEHAITSNEAFFLERLPRRVLVVGGGYIAVEFASIFNGLGAETTLLYRRDLFLRGFDRSVREHLRDELGKKGLDLQFNSDIARIDKQADGSLAATLKDGRVLEADCVFYATGRRPMLDDLGLENTAVKLTDKGFIAVDEHYQTSEPSILALGDVIGRVQLTPVALAEGMAVARRLFKPEEYRPVDYKLIPTAVFSLPNIGTVGLTEEEALSAGHKVKIFESRFRPMKLTLTDDQEKTLMKLVVDAHDDRVLGCHMVGAEAGEILQGIAVAMKAGATKQAFDETIGIHPTAAEEFVTLRTPTR
What is the function of this protein?
Maintains high levels of reduced glutathione in the cytosol.
What are the official names of this protein?
Glutathione reductase, GR, GRase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU1_XANC8
Sequence: MARAKFLREKLHVNVGTIGHVDHGKTTLTAALTKIGAERFGGEFKAYDAIDAAPEEKARGITISTAHVEYESAVRHYAHVDCPGHADYVKNMITGAAQMDGAILVCSAADGPMPQTREHILLSRQVGVPHIVVFLNKADMVDDAELLELVEMEVRELLSKYDFPGDDTPIIHGSARLALEGDQSDIGVPAILKLVEALDTFIPDPTRDVDRPFLMPVEDVFSISGRGTVVTGRIERGIIKVGDEIEIVGIRDTQKTTVTGVEMFRKLLDQGQAGDNAGLLLRGTKRDDVERGQVLCKPGSIKPHTEFEAEVYVLSKDEGGRHTPFFKGYRPQFYFRTTDITGACQLPEGVEMVMPGDNVKMVVTLINPVAMDEGLRFAIREGGRTVGAGVVAKIVK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu 1, EF-Tu 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLK6A_PLARH
Sequence: MKVFLLTILLCFLIAYCAGTNIFDPDNNPMCIPQGEKCVMRDFGCCLPYQCDWMKNRCK
What is the function of this protein?
Binds reversibly and blocks P/Q-type voltage-gated calcium channels (Cav).
What are the official names of this protein?
U-reduvitoxin-Pr6a, U-RDTX-Pr6a.
What is the protein family that this protein belongs to?
Belongs to the venom Ptu1-like knottin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PHNC2_PSE14
Sequence: MNDAIHVQGLNKTFSHKSALVDLALSIQPGEMVALIGASGSGKSTLLRHLAGLACCDRSNGGQVQVLGREVQSSGRLNSQVRRLRADIGYIFQQFNLVNRLSVLDNVLLGCLGRMPRWRGSLALFNREEKQRAMAALDRVGLADLATQRASTLSGGQQQRVAIARALTQRAEVILADEPIASLDPESARRVMEILADINRSDGKTVVVTLHQVDYAVRYCPRAVALKGGRIHFDGLAQDLSKQFLNDLYGADADASLMITERSRRVRQKPRLELAKV
What is the function of this protein?
Part of the ABC transporter complex PhnCDE involved in phosphonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphonates import ATP-binding protein PhnC 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.