PharMolix/UniProtQA huggingface dataset:
Protein: ODC_RAT
Sequence: MSASNVSLLHETCRQVAAGGCAGLVEICLMHPLDVVKTRFQVQRSVTDPQSYKSLRDSFQVIFRTEGLFGFYKGIIPPILAETPKRAVKFSTFELYKKFLGYMSLSPGLTFPIAGLGSGLTEAVVVNPFEVVKVGLQVNRNMFTEQPSTFAYARQIIKKEGWGFQGLNKGFTATLGRHGIFNMTYFGFYYNVKDNIPSSKDPTLEFLRKFGIGFVSGTVGSVFNIPFDVAKSRIQGPQPVPGEIKYRGCFKTMETVYREEGILALYKGLLPKVMRLGPGGGVMLLVYEYTYAWLQENW
What is the function of this protein?
Transports dicarboxylates across the inner membranes of mitochondria by a counter-exchange mechanism.  Can transport 2-oxoadipate (2-oxohexanedioate), 2-oxoglutarate, adipate (hexanedioate), glutarate, and to a lesser extent, pimelate (heptanedioate), 2-oxopimelate (2-oxoheptanedioate), 2-aminoadipate (2-aminohexanedioate), oxaloacetate, and citrate.  Plays a central role in catabolism of lysine, hydroxylysine, and tryptophan, by transporting common metabolite intermediates (such as 2-oxoadipate) into the mitochondria, where it is converted into acetyl-CoA and can enter the citric acid (TCA) cycle.
What are the official names of this protein?
Mitochondrial 2-oxodicarboxylate carrier, Solute carrier family 25 member 21.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RS6_LEIMA
Sequence: MKLNIAYPRNGTVKQFEISDEVLRRVQLQDYRLGNEVDGAIFGSEFKGYIFRLRGGSDKDGFPMVPGVLASSRVSLLVKRGAIGFNTFRGYQGERRRKNVRGCVLASDIALVNVTISKVGDQPIEGVTDTTAPRRLGPKRASKIRKLFNLSRTEDVRKYVVRRRVVKSGKKDRLKAPKIQRLITPRVKARRAKKAKDAIAKVRASAAERREYLRLIASNRRALRQRDHSKKHTRKVHAQRAEVAAFQKK
What is the function of this protein?
Component of the 40S small ribosomal subunit (By similarity).  Plays an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA (By similarity).
What are the official names of this protein?
40S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS6 family.
Protein: SPEB_SHIF8
Sequence: MSTLGHQYDNSLVSNAFGFLRLPMNFQPYDSDADWVITGVPFDMATSGRAGGRHGPAAIRQVSTNLAWEHNRFPWNFDMRERLNVVDCGDLVYAFGDAREMSEKLQAHAEKLLAAGKRMLSFGGDHFVTLPLLRAHAKHFGKMALVHFDAHTDTYANGCEFDHGTMFYTAPKEGLIDPNHSVQIGIRTEFDKDNGFTVLDACQVNDRSVDDVIAQVKQIVGDMPVYLTFDIDCLDPAFAPGTGTPVIGGLTSDRAIKLVRGLKDLNIVGMDVVEVAPAYDQSEITALAAATLALEMLYIQAAKKGE
What is the function of this protein?
Catalyzes the formation of putrescine from agmatine.
What are the official names of this protein?
Agmatinase, Agmatine ureohydrolase, AUH.
What is the protein family that this protein belongs to?
Belongs to the arginase family. Agmatinase subfamily.
Protein: DTDA_PYRHO
Sequence: MKVIMTTKVDKASMNIMNKLIENFGFKETEYVFDGNPVYKRGDVLILTTNDEMIYYDYLDREIENQLGFKPEIIAFASRHSSKQKLPALTTHVTGNWGKAMYGGKDESFAVAIPSAMKLSLLKMSELNDLGWTVCYEATHHGPTELEVPSFFIEIGSSEEEWINDRAGEIIAETIIYVLDNYEKGRSKFKVALGIGGGHYAPKQTKRALEGDLAFGHILPKYAQPVSRDVMIKALNRFGEKVEAIYVDWKGSRGETRQLAKSLAQELGLEFIKD
What is the function of this protein?
D-aminoacyl-tRNA deacylase with broad substrate specificity.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, D-tyrosyl-tRNA(Tyr) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DtdA deacylase family.
Protein: SPAG6_MOUSE
Sequence: MSQRQVLQVFEQYQKARTQFVQMVAELATRPQNIETLQNAGVMSLLRPLLLDVVPTIQQTAALALGRLANYNDDLAEAVVKGDILPQLVYSLAEQNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLEDFDPGVKEAAAWALGYIARHNTELSQAVVDAGAIPLLVLCIQEPEIALKRIAASALSDISKHSPELAQTVVDAGAIAHLAQMILNPDAKLKRQVLSALSQIAKHSVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNACTLIREIAKHTPELSQLIVNAGGVAAVIDCIGSCKGNIRLPGIMMLGYVAAHSENLAMAVIISKGVPQLSICLSEEPEDHIKAAAAWALGQLGRHTPEHARAVAVTNTLPVLLSLYMSPESSEDLQLKSKKAIKNILQKCTYLPALEPFLYDAPPNILKHVVGQFSKVLPHDSKARRLFVTSGGLKKVQEIKAEPGSLLQEYINSINNCYPEEIVRYYSPGYSDTLLQRVDSYQPL
What is the function of this protein?
Important for structural integrity of the central apparatus in the sperm tail and for flagellar motility.
What are the official names of this protein?
Sperm-associated antigen 6, Axoneme central apparatus protein, Protein PF16 homolog.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, cilium, flagellum. Cytoplasm, cytoskeleton, cilium axoneme. Note=Associated with microtubules. Detected on the sperm flagellum (PubMed:10684790). Localizes in the cilium axoneme in a SPEF1-dependent manner (PubMed:30535028).
Protein: RB_CHICK
Sequence: MPPKPLRRAGAARSQRTSPEGGAGTASPPGGTRLEVGEAEFVALCDALKAPDSVREKAWMTYQSLAAADGASAYNKKKKETWGVCIFIVAIDLDEMTFTFTELLKSLSISVCTFFQFLKEVDVNMDTVSTKVDSTVSRLKKKYDVLLALYHKFERTCGLIYLEQPSSEISAELSSVLVLKNYWITFLLAKGKVLQMEDDLVISFQLLLCVLDYFIKLSPPAMLKEPYKSAVTALTVNGSTRTPRRGQNRNARASKQIDTDTKVIEILCKEHDCNLDEVKNVYFTSFIPFLNSLGVVASNGLPEVDVLSKQYDELYLKNKDIDARLFLDHDETLQPDVIACSQLERTPRKNNPDEEVNHVLPQTPVRAAMNTIQQLMMILNSATDKPSDTLIAYFNNCTVNPEDSILKRVESLGHIFKKKFAEAVGQGCAEIGSQRYQLGVRLYYRVMESMLKSEEERLSVHNFSKLLNDNIFHTSLLACALEIVMATYGRTASQSDGTSAETDLSFPWILNVFDLKAFDFYKVIESFIKVEPSLTRDMIKHLERCEHRIMESLAWQSDSPLFDLIKQSKEREGQTDQPEPTSTLNLPLQHNHTAADLYLSPVRSPKKKASGHPQSGTSNPDAQPSATSQTQKPQKSTSLSLFYKKVFRLAYLRLHTLFFRLLSEHPDLEPLIWTLFQHTLQNESELMRDRHLDQIMMCSMYGICKVKNVDLRFKTIVSAYKELPNTNQETFKRVLIREEQYDSIIVFYNLVFMQKLKTNILQYASNRPPTLSPIPHIPRSPYQFSNSPRRVPAGNNIYISPLKSPYKFSDGFHSPTKMTPRSRILVSIGETFGTSEKFQKINQMVCNSESHVKRSAEPSDAPKPLKRLRFDIEGQDEADGGKHLPQESKFQQKLAEMTSTRTRMQKQKLNDGNDTSANEEK
What is the function of this protein?
Tumor suppressor that is a key regulator of the G1/S transition of the cell cycle.  The hypophosphorylated form binds transcription regulators of the E2F family, preventing transcription of E2F-responsive genes.  Both physically blocks E2Fs transactivating domain and recruits chromatin-modifying enzymes that actively repress transcription.  Cyclin and CDK-dependent phosphorylation of RB1 induces its dissociation from E2Fs, thereby activating transcription of E2F responsive genes and triggering entry into S phase.  RB1 also promotes the G0-G1 transition upon phosphorylation and activation by CDK3/cyclin-C.
What are the official names of this protein?
Retinoblastoma-associated protein, p104, pRb, Rb.
What is the protein family that this protein belongs to?
Belongs to the retinoblastoma protein (RB) family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MOBA_RHILW
Sequence: MTEFSIGRSEIAGVVLAGGRSQRMGRDKAGAMLGAESLLRHVLTRLSQQVLPVAVNADAAAEDVPVIPDRFRGKAGPLAGIHAAMVYAAGLPGITHVVTVSVDCPFFPADLVARLAAALERQSQIAIAASEGRSHPVFGLWPVTLAADLEAWMVTDEKRRVRDFLLRHDVTEVTFPLHPTRASLLDPFFNINTPDDLAEAERWLEALRA
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBD_NOSP7
Sequence: MTIAVGRAPSRGWFDVLDDWLKRDRFVFVGWSGILLFPCAFLALGGWLTGTTFVTSWYTHGLASSYLEGANFLTVAVSTPADSMGHSLLLLWGPEAQGDLTRWFQLGGLWPFVALHGAFGLIGFMLRQFEIARLVGIRPYNALAFSAPIAVFVSVFLMYPLGQSSWFFAPSFGVAAIFRFLLFLQGFHNWTLNPFHMMGVAGVLGGALLCAIHGATVENTLFEDGDGANTFRAFNPTQSEETYSMVTANRFWSQIFGIAFSNKRWLHFFMLFVPVTGLWMSAVGIVGLALNLRAYDFVSQELRAAEDPEFETFYTKNILLNEGIRAWMAPQDQPHEQFVFPEEVLPRGNAL
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.  D2 is needed for assembly of a stable PSII complex.
What are the official names of this protein?
Photosystem II D2 protein, PSII D2 protein, Photosystem Q(A) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: PHOSP_VSNJM
Sequence: MDSIDRLKTYLATYDNLDSALQDANESEERREDKYLQDLFIEDQGDKPTPSYYQEEESSDSDTDYNAEHLTMLSPDERIDKWEEDLPELEKIDDDIPVTFSDWTQPVMKENGGEKSLSLFPPVGLTKVQTDQWRKTIEAVCESSKYWNLSECQIMNSEDRLILKGRIMTPDCSSSIKSQNSIQSSESLSSSHSPGPAPKSRNQLGLWDSKSTEVQLISKRAGVKDMMVKLTDFFGSEEEYYSVCPEGAPDLMGAIIMGLKHKKLFNQARMKYRI
What is the function of this protein?
Essential component of the RNA polymerase transcription and replication complex.  Binds the viral ribonucleocapsid and positions the L polymerase on the template.  May act as a chaperone for newly synthesized free N protein, so-called N(0).  Plays a role in virion assembly (By similarity).
What are the official names of this protein?
Phosphoprotein, Protein P, Protein M1.
What is the protein family that this protein belongs to?
Belongs to the vesiculovirus protein P family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: KAIB2_SYNY3
Sequence: MENLNALSGNQNLEVWQLRLYVAGQTPKSVTAFINLKKICEEYLNGQYQIEIIDLTQQPELAIEDSILALPTLVRKLPEPIKKIIGDLSNTEKVLVGLQILPSMDWKI
What is the function of this protein?
An paralog of KaiB1, the major clock oscillator protein in this species.  A metamorphic protein which may reversibly switch between an inactive tetrameric fold and a rare thioredoxin-like monomeric fold (KaiB(fs)).
What are the official names of this protein?
Circadian clock protein KaiB2.
What is the protein family that this protein belongs to?
Belongs to the KaiB family.
Protein: RL24_METC4
Sequence: MAAKIKKGDTVVVLTGRDAGRSGEVIQVMPKEDKAFVRGVNLVKKHQRQTQNQEGGIISKEAAIQLSNIAVADANGKPTRVGFRILDDGRKVRFAKTTGDQIDG
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: MSRA_CORML
Sequence: MAWFFAPEPVMVTADEALKGGRHTVLENPAPHTVLGTPVTGPWKEGQQRIWIGLGCFWGVEQMYWQMDGVEGTSVGYAGGFTPNPTYREVCSGRTGHTEIVEVVYDPSKISLEQLVARGLEAHDPTQGFRQGNDVGTQYRSAYYTENEEGAARVKAVVDAYGETLKQHGFGEITTEIGVISPSEYFLAEDYHQQYLDKNPDGYCPHHSTGIPCGVEA
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: NPH2_RFVKA
Sequence: MENHLPNIFYFPNCVTTFPYRYTQKELDDMKPDERERFKYATFPIIKHRWSHAYVVKDNHVFKLNVETSKRLRRATPPTLSVPVSMNTMLREYITQDGTKISFECYSYLTCKKATSLHDLDDNAIRGLVEGGNRLQLFTNSVGSVKDTVGIFGNPNPFMKVPLKSLHPSMQCKIFESWIHHVPVVLTGDTGVGKTSQVPKLLLWFNYLFGGFVNLSTITFDVQEKPIVLSLPRVALVKLHSETLLTSLGFNEIHKSPVSLKFGNMQEQFVNTRFRRYGIVFSTHKITLNTLFNYSTVILDEVHEHDQTGDIIIAVCRKYIRKLDSLFLMTATLEDDRQRIEEFFTESVFVHIPGGTLFSISEAYVKNSNDSLNKFMYIEEEKRNLVNAIKTYTPPKQSSGIVFVSTVSQCDVYKQYLSERLPYKFYIIHGKIQNINDLLSDIYDNEGVSIIISTPYLESSVTVQNATHVYDTGRVYIPSPYGGREVFISKSMRDQRKGRVGRVKPGMYIYFYDVSELRPIKRIDFEFLHNYVLYSKVFDLQLPEDLFVKPTNMTRLRDVIEYIRSFNISDGVWTRLLSSYYIHILEYAKVYARGGQSAAALDSFERTGNLTDDALDAIKSLNMRAKIISHRKASTHTYALMCRLLFGVYAGKTFIAYHKRPLTGYITMITEHSFIPEY
What is the function of this protein?
NTP-dependent helicase that catalyzes unidirectional unwinding of 3'tailed duplex RNAs and plays an important role during transcription of early mRNAs, presumably by preventing R-loop formation behind the elongating RNA polymerase.  Might also play a role in the export of newly synthesized mRNA chains out of the core into the cytoplasm.  Required for replication and propagation of viral particles.
What are the official names of this protein?
RNA helicase NPH-II, Nucleoside triphosphatase II, NTPase II, Nucleoside triphosphate phosphohydrolase II, NPH II.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
What are the subcellular locations of this protein?
Virion. Note=Localizes to the virion core.
Protein: THII_STRSY
Sequence: MNYSEIMIRYGELSTKGKNKMRFVNKLRNNIKHVLSVYPEVTVYFDRDRGHVYLNGADYQEVSASLKKIFGIQNFAPSYKIEKSVPALKEAVVEIMQTIYKEGMTFKIAARRSDHSFELDSRDLNQVLGDAVFTAIPNVQVQMKSPDITLRVEIRPDAAYISHEEIKGAGGLPVGTSGKGTLMLSGGIDSPVAGYLALKRGVEIEALHFASPPYTSPGALKKAHDLTRKLTAFGGNITFIEVPFTEIQEEIKEKAPEAYLMTLTRRFMMRITDRVREERGAMVIINGESLGQVASQTLESMQAINAVTNTPVIRPVVTMDKLEIIDIAQEIDTFDISIQPFEDCCTIFAPDRPKTNPKIKNVEQYEARMDVEGLVERAVAGIIVTEITPKEEVKDEVDSLIEDLL
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBE_GRATL
Sequence: MSGGSTGERPFSDIITSIRYWVIHSITIPSLFVAGWLFVSTGLAYDVFGTPRPNEYFTQDRQQVPLVNDRFSAKQELEDLTKGI
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit alpha, PSII reaction center subunit V.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: BANP_BOVIN
Sequence: MMSEQDLADVVQIAVEELSPGHPVVLENHVVTDEDEPALKRQRLEINCQDPSIKSFLYSINQTICLRLDSIEAKLQALEATCKSLEEKLDLVTNKQHSPIQVPMVAGSPLGATQTCNKVRCVVPQTTVILNSDRQNAVVAKMEDPLSGRAPEPLENVISNAVPGRRQNTIVVKVPGQEDSHNEDGESGSEASDSVSNCGQSGSQNIGNNVTLITLNSEEDYPNGTWLGDENNPEMRVRCAIIPSDMLHISTNCRTAEKMALTLLDYLFHREVQAVSNLSGQGKHGKKQLDPLTIYGIRCHLFYKFGITESDWYRIKQSIDSKCRTAWRRKQRGQSLAVKSFSRRTPSSSSYGASETMMSTPPPSSELQQPPPQALHYALANAQQVQIHQIGEDGQVQVGHLHIAQVPQGEQVQITQDSEGNLQIHHVGQDGQVLQGAQLIAVASSDPAATGVDGSPLQGSDIQVQYVQLAPVTDHTAAAQAADALQPTLQPEMQLEHGAIQIQ
What is the function of this protein?
Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function.  Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer.  Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels.  Promotes TP53 activation, which causes cell cycle arrest (By similarity).
What are the official names of this protein?
Protein BANP.
What is the protein family that this protein belongs to?
Belongs to the BANP/SMAR1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NANE_STRPM
Sequence: MPDKPTKEKLMEQLKGGIIVSCQALPGEPLYSETGGIMPLLAKAAQEAGAVGIRANSVRDIKEIQAITDLPIIGIIKKDYPPQEPFITATMAEVDQLAALNIAVIAMDCTKRDRHDGLDIASFIRQVKEKYPNQLLMADISTFDEGLVAHQAGIDFVGTTLSGYTPYSRQEAGPDVALIEALCKAGIAVIAEGKIHSPEEAKKINDLGVAGIVVGGAITRPKEIAERFIEALKS
What is the function of this protein?
Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).
What are the official names of this protein?
Putative N-acetylmannosamine-6-phosphate 2-epimerase, ManNAc-6-P epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanE family.
Protein: MED11_HUMAN
Sequence: MATYSLANERLRALEDIEREIGAILQNAGTVILELSKEKTNERLLDRQAAAFTASVQHVEAELSAQIRYLTQVATGQPHEGSSYSSRKDCQMALKRVDYARLKLSDVARTCEQMLEN
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 11, Mediator complex subunit 11.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 11 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: AROD_STAS1
Sequence: MTEVKVAVTIAPEQELSQSTIDDLIQFQDSIDIIELRIDQWTNLNEIAIEKVVEDLQSLKLNKKLLVTYRTSNQGGLGDFGEDDYIQILRKIANCQNIDMLDIEFDQTRSLNILQELIELAHKNQVQVVLSHHNFKETPKLEALKHLFYKMQQLESDYIKVAVMPHGKQDVLNLLNAMSDTADVVSQHVVGIAMSKIGLISRTAQGVFGGSISYGCLDTPKAPGQIHVSTLKKQLSMYE
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: AROF_STRLI
Sequence: LQYIERLDPEREPGRLTFIVRMGADKIRDKLPELVERSPPPATVAWITDPMHGNTYEAAPVHKTRRFDDVLDEVKGFFEVHKSLGTHPGGIHVELTGDDVTECVGGGDEIFVDDLHQRYETACDPRLNRSQSLDLAFLVAEMYRDQ
What are the official names of this protein?
Phospho-2-dehydro-3-deoxyheptonate aldolase, 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase, DAHP synthase, Phospho-2-keto-3-deoxyheptonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class-II DAHP synthase family.
Protein: CH10_DICDI
Sequence: MSGVKKFIPLLDRILVEKISNQATKTSGGIFIPTNKDAPTNNAKVIAVGTGSVKLDGSFIDPIVKEGDIVLINPKARSNTVPWGDKTYHLLSENDILGIIEN
What is the function of this protein?
Eukaryotic CPN10 homolog which is essential for mitochondrial protein biogenesis, together with CPN60.  Binds to CPN60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity).
What are the official names of this protein?
10 kDa heat shock protein, mitochondrial, Hsp10, 10 kDa chaperonin, Chaperonin 10, CPN10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: ANMK_SALPA
Sequence: MKSGRFIGVMSGTSLDGVDVVLAAIDETMVAQQASLTWPIPVHLKKGILDICQGQPLTLSQLGQLDTQLGRLFAQAVNALLAQQRLQPRDIVAIGCHGQTVWHEPTGEAPHTLQIGDNNHIVAHTGITVVGDFRRRDIALGGQGAPLVPAFHHALLGHPTEKRMVLNIGGIANLSLLFPGQAVRGYDTGPGNMLMDAWIWRQCAQPYDKDAAWAKEGQVILPLLQKMLRDPYFAASAPKSTGREYFNYGWLERHLAAFPGADARDVQATLAELTAVSIAQQVLLNGGCERLMVCGGGGRNPLVMARLAALLTGIEVSTTDKAGISGDDMEALAFAWLAWRTLAGLPGNLPSVTGATEASVLGAIYPANPITQS
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: CSE2_THET8
Sequence: MSPGERFLDWLKRLQGQKAWTAARAAFRRSLAFPPGAYPRAMPYVEPFLAKGDWRQEEREAHYLVAALYALKDGDHQVGRTLARALWEKAQGSASVEKRFLALLEADRDQIAFRLRQAVALVEGGIDFARLLDDLLRWFSPERHVQARWAREYYGAGASEEEKKKEVEA
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) (By similarity).
What are the official names of this protein?
CRISPR-associated protein Cse2, CRISPR type I-E/ECOLI-associated protein CasB/Cse2.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated CasB/Cse2 family.
Protein: CH10_CHLT3
Sequence: MNLKPLADRVIVKPSPAEEKTKGGLYIPDSGKEKPQHGEVVAVGPGKAADNGTVVAMEVQVGQKVLYGKYSGTEVTVDGEDYLIMRESDIFAIIG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: END4_AKKM8
Sequence: MPYIGCHLSSAKGYEAMGRVALSIGANTFQFFTRNPRGSKAKAIDEQDIARFLELARNNGFGTLLAHAPYTLNPCSADPSVARFAAQVLKEDLELMEHLPGNLYNFHPGCHVGQGVEKGIELVADQLNDVLSPEQKTIVLLETMSGKGSEVGRTFEELAAIMERVDLKDKLGVCLDTCHVYSAGYDIVNRLDSVLEHFDAVLGLERLRAIHLNDSMTPFSSFKDRHETIGKGSLGEQAFINIINHPVLRELPFFLETPRDDAGHGEEITWLKEHYRN
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: MTR1_TRYCC
Sequence: MSEVTDKTVEFLLRHSASRRPPDIGSLKEKAFERVNWRDAFDRFQETERLTLWETKSELDGVDEGAYRVARDALFPFAVSGSQGAVSFGNRAGHKLREVMEATGVWEHLQRETSGQKGAVVFADVCGGPGAFSQALFEMSRQYKLRMRGFGMTLRNVRGLDWYSSLPLGKFLPTYGIDGTGDIFNLANIEALLSLTIRERLKLVVADGGFNVPFNIANYQETLSGRILFGQWLAALKLLRPGGCFILKLFDTFSPLSRALLYLSTYLYDRVHVVKPRHSRVVNSERYLVCLGFLGTPGPWMEYFEHCYQVGFSDNDSIPKIMPTSWVMEDKTFMKDLKQMNSTIASNQTLALKMVLAKLQPS
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that mediates RNA cap1 2'-O-ribose methylation to the 5'-cap structure of spliced leader and U1 small nuclear RNAs.  Methylates the ribose of the first nucleotide of a m(7)GpppG-capped RNA to produce m(7)GpppNmp (cap1).  Cap1 modification is linked to higher levels of translation.  Recognizes a guanosine cap on RNA independent of its N(7) methylation status.
What are the official names of this protein?
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1, Cap1 2'O-ribose methyltransferase 1, MTr1.
What are the subcellular locations of this protein?
Nucleus.