PharMolix/UniProtQA huggingface dataset:
Protein: PDXJ_CHLP8
Sequence: MRLAVNIDHIATLRNARNEGHPDPVEAAILAEQSGAAGIVCHLREDRRHIKDDDLERLREAIDTKLDLEMAMTSEMQSIALRVKPELVTLVPEKREELTTEGGFAIHTHFKRLTEFIKPLRDHGVEVSIFIEPEDDAIELAAEAGANLVELHTGPYSLATGDKQIAYELERIRTAARIAREAGLAVVAGHGLSVHNIAPFRELHDIEEVSIGHALIARAVLVGLPVAIQELLDHISR
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AAAT_RABIT
Sequence: MVADPPKGDPKGLAAVEPTANGAPAQDPLEDSGAAVGRCCSSRDQVRRCLRANLLVLLTVVAVVAGVALGLAVSGAGGALALGPARLIAFAFPGELLLRLLKMIILPLVVCSLVGGAASLDPSALGRLGAWALLFFLVTTLLASALGVGLALALQPGAAFAAMNASLSSTGAVEQTPSKQVLDSFLDLLRNIFPSNLVSAAFRSYSTSYEEKNFNGTLVKVPVAHEEEGMNILGLVVFAIVFGVALRKLGPEGEPLIRFFNSFNDATMVLVSWIMWYAPVGILFLVASKIVEMDDVGVLFASLGKYILCCLLGHAIHGLLVLPLIYFLFTRKNPYRFLWGILTPLAMAFGTSSSSATLPLMMKCVEERNGVAKHISRFVLPIGATVNMDGAALFQCVAAVFIAQLNRQSLDFVKIITILVTATASSVGAAGIPAGGVLTLAIILEAVSLPVSEISLILAVDWLVDRSCTIINVEGDAFGAGLLQHYVDRTEQRGSEPELTQVKSEVPLGSLPAPNEEGNPLLRHSPGAAGDAGACEKESVM
What is the function of this protein?
Sodium-coupled antiporter of neutral amino acids.  In a tri-substrate transport cycle, exchanges neutral amino acids between the extracellular and intracellular compartments, coupled to the inward cotransport of at least one sodium ion (By similarity) (PubMed:9227483).  The preferred substrate is the essential amino acid L-glutamine, a precursor for biosynthesis of proteins, nucleotides and amine sugars as well as an alternative fuel for mitochondrial oxidative phosphorylation.  Exchanges L-glutamine with other neutral amino acids such as L-serine, L-threonine and L-asparagine in a bidirectional way.  Provides L-glutamine to proliferating stem and activated cells driving the metabolic switch toward cell differentiation (By similarity).  The transport cycle is usually pH-independent, with the exception of L-glutamate.  Transports extracellular L-glutamate coupled to the cotransport of one proton and one sodium ion in exchange for intracellular L-glutamine counter-ion.  May provide for L-glutamate uptake in glial cells regulating glutamine/glutamate cycle in the nervous system (By similarity).  Can transport D-amino acids.  Mediates D-serine release from the retinal glia potentially affecting NMDA receptor function in retinal neurons (By similarity).  Displays sodium- and amino acid-dependent but uncoupled channel-like anion conductance with a preference SCN(-) >> NO3(-) > I(-) > Cl(-) (By similarity).  Through binding of the fusogenic protein syncytin-1/ERVW-1 may mediate trophoblasts syncytialization, the spontaneous fusion of their plasma membranes, an essential process in placental development (By similarity).
What are the official names of this protein?
Neutral amino acid transporter B(0), ATB(0), Sodium-dependent neutral amino acid transporter type 2, Solute carrier family 1 member 5.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. SLC1A5 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Melanosome.
Protein: MNMA2_CALS4
Sequence: MQKNNRVVVGMSGGVDSSVAAYLLKEQGYEVIGVTMQIWQDKDEEAVRVEGGCCSLAAVNDARRVANKIGIKYYVMNFKDVFKEKVIDYFVDEYLRGRTPNPCIACNKYIKFEELLKRAWMIDAYYVATGHYAIKEYDEERGRYLLKKSVDTSKDQTYVLYNLTQTQLEHILFPLGKYKKDKVRELAKNLGLPVASKPDSQEICFVTDNDYGKFIRENAKEEIKPGEFRDTRGRFLGYHKGIIHYTIGQRKGLGISVGKPLYVVDIDAENNVVVLGYGDEVYGDELISYNNNFISIDKLEKEMRVKAKIRYTAKEQDAVIRPLEDGRVFVKFDNPQRAITPGQSVVFYDGDIVVGGGIIERKVR
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA 2.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_HUMAN
Sequence: MLSVRVAAAVVRALPRRAGLVSRNALGSSFIAARNFHASNTHLQKTGTAEMSSILEERILGADTSVDLEETGRVLSIGDGIARVHGLRNVQAEEMVEFSSGLKGMSLNLEPDNVGVVVFGNDKLIKEGDIVKRTGAIVDVPVGEELLGRVVDALGNAIDGKGPIGSKTRRRVGLKAPGIIPRISVREPMQTGIKAVDSLVPIGRGQRELIIGDRQTGKTSIAIDTIINQKRFNDGSDEKKKLYCIYVAIGQKRSTVAQLVKRLTDADAMKYTIVVSATASDAAPLQYLAPYSGCSMGEYFRDNGKHALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDAFGGGSLTALPVIETQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTRAMKQVAGTMKLELAQYREVAAFAQFGSDLDAATQQLLSRGVRLTELLKQGQYSPMAIEEQVAVIYAGVRGYLDKLEPSKITKFENAFLSHVVSQHQALLGTIRADGKISEQSDAKLKEIVTNFLAGFEA
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Subunits alpha and beta form the catalytic core in F(1).  Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.  Subunit alpha does not bear the catalytic high-affinity ATP-binding sites (By similarity).  Binds the bacterial siderophore enterobactin and can promote mitochondrial accumulation of enterobactin-derived iron ions (PubMed:30146159).
What are the official names of this protein?
ATP synthase subunit alpha, mitochondrial, ATP synthase F1 subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. Cell membrane; Peripheral membrane protein; Extracellular side. Note=Colocalizes with HRG on the cell surface of T-cells (PubMed:19285951).
Protein: PYRH_CERS5
Sequence: MTSEAAPASTAVTYKRVMLKISGEALMGDQGYGLHPPTVQRIAREVQAVHRLGVEICMVIGGGNIFRGLQGSAQGMERTTADYMGMLATVMNALAMQAALESLGIFTRVISAIPMDQVCEPYIRRRAVRHLEKKRVCIFAAGTGNPYFTTDTAATLRANEMACQAIFKGTKVDGVYDKDPRKFADARRYETVSYDECLQKHLGVMDASAIALARDNDLPIIVFSLDEPGGFCGILRGEGTYTRVQG
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_RHORT
Sequence: MFAVIKTGGKQYKVAENDVIDIEKLEADEGATVEFDSVLALGDTVGLPTIAGAKVTGEVLSQFRGEKVIIFKKHRRQNYRRKNGHRQFLTRVRITGFAGV
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: NAC23_ORYSI
Sequence: MAMTPQLAFSRMPPGFRFQPTDEQLVVDYLQRRTAAQPCVTPDITDIDVYNVDPWQLPAMAMYGSDHDRYFFTMAAREAQARRTTPSGFWKPTGTKKTIFVVAGGHEVPTAVKRRFVFYLGHHQPSGSSNNNKTSWIMHEYRLMNSPRAAVPSSSSVNRLPTDDLTEEMVLCRISNKDLPKPPFIHNGLLQFSSVGLNGDGYNYLILDHLEPPAMEYPNVDIGNVDDAAAADDDPGDLDEEIDDSMQRNHGG
What is the function of this protein?
Transcription factor involved in the regulation of seed size (PubMed:27872632).  Possesses transactivation activity in yeast (PubMed:27872632).
What are the official names of this protein?
NAC domain-containing protein 23, ONAC023, OsNAC6, Protein THERMOSENSITIVE MALE STERILITY 5.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: GIP_RAT
Sequence: MVALKTCSLLLVLLFLAVGLGEKEEVEFRSHAKFAGPRPRGPRYAEGTFISDYSIAMDKIRQQDFVNWLLAQKGKKNDWKHNLTQREARALELAGQSQRNEEKEAQGSSLPKSLSDEDVLRDLLIQELLAWMADQAELCRLRSQ
What is the function of this protein?
Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion.
What are the official names of this protein?
Gastric inhibitory polypeptide, GIP, Glucose-dependent insulinotropic polypeptide.
What is the protein family that this protein belongs to?
Belongs to the glucagon family.
What are the subcellular locations of this protein?
Secreted.
Protein: CAIC_SALHS
Sequence: MDIVGGQNLRQMWDDLAGVYGDKTALIFESCEGIVRQFSYASLNEEINRTANLFYSLGIRKGDRVALHLDNCPEFIFCWFGLAKIGAIMVPINARLLGEESAWILQNSQVSLLVTSAQFYPMYREIRQDNSTPLNHICLIGEQLPADDGVSHFTQLQARQSATLCYTPVLSTDDTAEILFTSGTTSRPKGVVITHYNLRFAGYYSAWQIALRDDDVYMTVMPAFHIDCQCTAAMPAFSAGSTFVLLEKYSARAFWDQVRKYQATVTECIPMMIRTLMVQPAAPTDRQHHLREVMFYLNLSEQEKDDFTERFGVRLLTSYGMTETIVGIIGDRPGDKRRWPSIGRVGFSYEAEIRDDQNRPLPAGEIGEICIKGIPGKTIFKEYYMQPEATAKALEPEGWLHTGDSGYQDEDGYFYFVDRRCNMIKRGGENVSCVELENIISAHPKIQDIVVVGIKDAIRDEAIKAFIVLNEGETLSEAEFFSFCENNMAKFKVPSFMEIRTDLPRNCSGKIIKKNLK
What is the function of this protein?
Catalyzes the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the CaiB reaction cycle.  Also has activity toward crotonobetaine and gamma-butyrobetaine.
What are the official names of this protein?
Crotonobetaine/carnitine--CoA ligase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: RL3_AZOPC
Sequence: MPGLIGKKIGMTSIFSVEGKNLPCTVMEVGPCVVTQVKTVDKDGYEAVQVGFEDKKEKHTTKPERGHFKRAGVSFKRYLAEFKEQGKYKEGDVITVDFFNKGIYVDVVGISKGKGFQGVVKRHGFRGVGEATLGQSDRQRHPGSIGACSYPAKVFKGTRMAGQMGNTKVTIQNLEVIELISKYNLLIVKGSVPGSKGSILIVKK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: DNAK_THET8
Sequence: MAKAVGIDLGTTNSVIAVLEGGKPVVLENAEGERVTPSVVAFRDGETLVGRMAKRQAVLNPEGTIFEIKRFIGRRFEEVQEEAKRVPYKVVPGPDGGVRVEVKGKLYTPEEISAMILRKLVEDASKKLGEKITKAVITVPAYFNNAQREATANAGRIAGLEVLRIINEPTAAALAYGLDKKGNETVLVFDLGGGTFDVTILEIGEGVFEVKATSGDTHLGGSDMDHAIVNWLAEEFKKEHGVDLKADRQALQRLIEAAEKAKIELSSTLETTISLPFIALDPASKTPLHLEKKLTRAKFEELIQPLLKRLRGPVEQALKDAGLTPAQIDEVILVGGATRVPAVQQVVRELLGKEPNRSVNPDEVVAMGAAIQAGVLMGEVRDVVLLDVTPLSLGVETKGGVMTVLIPRNTTIPTRKCEIFTTAEHNQTAVEIHVLQGERPMAQDNKSLGRFRLEGIPPMPAGVPQIEVCFDIDANGILHVTAKERSTGREASITIQNTTTLSEEEIQRIIEEAKRHAEEDRRRREHAELKNALDSARVQAERVLQERQGAPEARARLEAAIGKAKELVERDAPDPELKAATEELLKAVEEYEKGAQAASGKGPDDVIDADYKPAD
What is the function of this protein?
Cooperates with DnaJ, GrpE and ClpB to reactivate heat-inactivated proteins.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: SHTX5_STIHA
Sequence: MASFRTLFACVVILCCVLWSSMARYGEDMEVETEMNKRDEGVRCTGQHASSFCLNGGTCRHIASLGEYYCICPGDYTGHRCDQKSG
What is the function of this protein?
Has both toxic and EGF activity.  Its EGF activity consists of rounding cells (morphological change) and inducing tyrosine phosphorylation of the EGFR in A431 cells, but with a lower potency that human EGF.
What are the official names of this protein?
OMEGA-stichotoxin-Shd4a, OMEGA-SHTX-Shd4a, EGF-like peptide SHTX V, SHTX-5.
What is the protein family that this protein belongs to?
Belongs to the EGF domain peptide family.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: CTBP2_MOUSE
Sequence: MALVDKHKVKRQRLDRICEGIRPQIMNGPLHPRPLVALLDGRDCTVEMPILKDLATVAFCDAQSTQEIHEKVLNEAVGAMMYHTITLTREDLEKFKALRVIVRIGSGYDNVDIKAAGELGIAVCNIPSAAVEETADSTVCHILNLYRRNTWLYQALREGTRVQSVEQIREVASGAARIRGETLGLIGFGRTGQAVAVRAKAFGFSVIFYDPYLQDGIERSLGVQRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFAQGPLKDAPNLICTPHTAWYSEQASLEMREAAATEIRRAITGRIPESLRNCVNKEFFVTSAPWSVIDQQAIHPELNGATYRYPPGIVGVAPGGLPPAMEGIIPGGIPVTHNLPTVAHPSQAPSPNQPTKHGDNREHPNEQ
What is the function of this protein?
Corepressor targeting diverse transcription regulators.  Isoform 2 probably acts as a scaffold for specialized synapses (By similarity).  Functions in brown adipose tissue (BAT) differentiation.
What are the official names of this protein?
C-terminal-binding protein 2, CtBP2.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
What are the subcellular locations of this protein?
Nucleus. Synapse.
Protein: YCO6_SCHPO
Sequence: MVENVNINNKRAGKMSAAPTPHNTPSGTSAPNFGAKAPQVNTIDEGDENLEAIDGKLGSLLHLTSEGVSELPEAVQRRISGLRGLQKRYSDLESQFQKELFELEKAYAKKYAPIFKRRSEVVRGADEPTEEEIKKGEAADENEKKEPTSSESKKQEGGDDTKGIPEFWLTAMKNVLSLSEMITPEDEGALSHLVDIRISYMEKPGFKLEFEFAENPFFTNKILTKTYYYMEESGPSNVFLYDHAEGDKVDWKENADLTVRTVTKKQRNKNTKQTRVVKVSVPRDSFFNFFNPPTPPSEEDEESESPELDELLELDYQIGEDFKEKLIPRAVEWFTGEALALENYDGFSDLDVEEDEDDVESSSNEEVSDSDEEDSDSKHTAHGQQNAAECRQQ
What are the official names of this protein?
Putative nucleosome assembly protein C364.06.
What is the protein family that this protein belongs to?
Belongs to the nucleosome assembly protein (NAP) family.
What are the subcellular locations of this protein?
Nucleus.
Protein: AROK_SALA4
Sequence: MAEKRNIFLVGPMGAGKSTIGRQLAQQLNMEFYDSDQEIEKRTGADVGWVFDVEGEDGFRNREEKVINELTEKQGIVLATGGGSVKSRETRNRLSARGVVVYLETTIEKQLARTQRDKKRPLLQVEAPPREVLEALANERNPLYEEIADVTIRTDDQSAKVVANQIIHMLESN
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase 1, SK 1.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPX_ALIF1
Sequence: MTDKRKDENSGKLLYCSFCGKSQHEVRKLIAGPSVYVCDECVDLCNDIIREELKDNTLSPKESSEELPTPRNIREHLDDYVIGQEHAKKVLAVAVYNHYKRLRNGDTTKDGVELGKSNILLIGPTGSGKTLLAETLARFLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDPAKAERGIVYIDEIDKISRKSENPSITRDVSGEGVQQALLKLIEGTIASVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVIEQRVATGTGIGFGADVRSKENEATIGDLFKQIEPEDLVKFGLIPEFIGRLPVTTTLTELDEEALVQILSQPKNALTKQYGALFDLEGAELEFREDALKAIAKKAMDRKTGARGLRSILEAVLLETMYELPSKEGVSKVVIDESVINGESEPLLIFENTETKAISAE
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: RL18_PYRFU
Sequence: MAHGPRYRVPFRRRREGKTNYRKRLKLLKSGKPRLVVRKSLNHHIAQIIVYDPKGDRTLVSAHTRELIRDFGWKGHCGNTPSAYLLGLLIGYKAKQAGIEEAILDIGLHPPVRGSSVFAVLKGAVDAGLNVPHSPEIFPDEYRIRGEHIAEYAKMLKEQDEEKFRRQFGGYLVKGLDPEKLPEHFEEVKARIIEKFEGEGARE
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18, Large ribosomal subunit protein uL18, PfL18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: DNAK1_SYNY3
Sequence: MGKVIGIDLGTTNSCASVLEGGKPIVITNTEGGRTTPSIVGFTKGSQRLVGQLAKRQSVTNAENTVYSIKRFIGRRWDDTVEERSRVPYNCVKGRDDTVSVSIRGQSYTPQEISAMILQKLKADSEAFLGEPVTQAVITVPAYFTDAQRQATKDAGTIAGLEVLRIINEPTAAALAYGLDKQETEELILVFDLGGGTFDVSLLQLGNGVFEVLSTSGNNHLGGDDFDNCVVQWMAESFKQKENIDLSTDKMAIQRLREAAEKAKIELSSMLNTTINLPFITADESGPKHLEMELARSQFEELTKQLLEDTRVPLTQALDDGEIRASDVHRVILVGGSTRIPAIQRVIQEFFPDSQLERSVNPDEAVALGAAIQAGVIGGEVEDVLLLDVTPLSLGLETLGEVTTKIIERNTTIPTSRSEVFSTAVDGQTSVEIHVIQGERAMARDNKSLGKFLLAGIPPAPRGMPQIEVSFEIDVNGILKVSAQDQGTGKEQSIVISHTGGLSGGEIEKMRQEAQQYAAQDQLRLRMMELQNQADSLFHTYETTLQESGELVREELKSSGKQKKDQLAIALRTPNTPVEKLQTLVEEFRQIILLIGTEVYQQGKGAASNEFANFVQGTSSGTSQMIESLETNLNPIQASSGITMTPGTMINGTVNPGGMDYVETAPVYGLDDGEEFDFDADETVYSDYEAID
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein dnaK1, HSP70-1, Heat shock 70 kDa protein 1, Heat shock protein 70-1.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: ZNTB_ECOBW
Sequence: MEAIKGSDVNVPDAVFAWMLDGRGGVKPLENTDVIDEAHPCWLHLNYVHHDSAQWLATTPLLPNNVRDALAGESTRPRVSRLGEGTLITLRCINGSTDERPDQLVAMRVYMDGRLIVSTRQRKVLALDDVVSDLEEGTGPTDCGGWLVDVCDALTDHSSEFIEQLHDKIIDLEDNLLDQQIPPRGFLALLRKQLIVMRRYMAPQRDVYARLASERLPWMSDDQRRRMQDIADRLGRGLDEIDACIARTGVMADEIAQVMQENLARRTYTMSLMAMVFLPSTFLTGLFGVNLGGIPGGGWQFGFSIFCILLVVLIGGVALWLHRSKWL
What is the function of this protein?
Zinc transporter.  Acts as a Zn(2+):proton symporter, which likely mediates zinc ion uptake.
What are the official names of this protein?
Zinc transport protein ZntB.
What is the protein family that this protein belongs to?
Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RIBL_PYRHO
Sequence: MGSDRKIRVVVGGVFDIIHAGHVHFLKMAKELGDELIVIVAHDETVKKRKGRPPINPAEDRAEVLKAIRYVDDVVIGKPGEISLDLIKRLKPDVIALGPDQDFDCEDLKRKLKSIGLNVEVIRLPYLYKKDRAKTSKIIERITEIFCD
What is the function of this protein?
Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
What are the official names of this protein?
FAD synthase, FMN adenylyltransferase, Flavin adenine dinucleotide synthase.
What is the protein family that this protein belongs to?
Belongs to the archaeal FAD synthase family.
Protein: RL24_XYLFA
Sequence: MASRIKKGDQVIVIAGKDKGKQGEIIRIDGHRVVVSNVNIVKRHTKPNPQRSISGGLIDREAPIHVSNIQVLNPMTGKGDRVGFKILDDGCKLRIFRSTGEVIGA
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: GCSH_AZOSB
Sequence: MSTIPNDLKYTKSHEWIRLEADGTLTVGVTDHAQAALGDVVFLELPEAGRVVSAGEACAVIESVKAASDIYAPVAGEVIARNDSVTDAPESVNADAYAAWLFKLKPANAGDTSALLDAAGYATEIAD
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: KDSA_ECO45
Sequence: MKQKVVSIGDINVANDLPFVLFGGMNVLESRDLAMRICEHYVTVTQKLGIPYVFKASFDKANRSSIHSYRGPGLEEGMKIFQELKQTFGVKIITDVHEPSQAQPVADVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQFVSPGQMGNIVDKFKEGGNEKVILCDRGANFGYDNLVVDMLGFSIMKKVSGNSPVIFDVTHALQCRDPFGAASGGRRAQVAELARAGMAVGLAGLFIEAHPDPEHAKCDGPSALPLAKLEPFLKQMKAIDDLVKGFEELDTSK
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NFUA_YERPY
Sequence: MITITDAAQSHFAKLLANQEEGTQIRVFVINPGTPTAECGVSYCPPDAVEATDTELKFEQLSAYVDELSVPYLQDAEIDFVTDQLGSQLTLKAPNAKMRKVDDSAPLMERVEYVLQSQINPQLAGHGGRVTLMEITPEGLAILQFGGGCNGCSMVDVTLKEGIEKELLQKFPELKGVRDLTEHQRGEHSYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: VPS72_SCHPO
Sequence: MSATESLVAGRTRRANAGNKMRELLEKEHLRMTQQNAEIEKEDEEYNIEEEEEAERDIEISSESSDEEAELKKLEEEGEEVEKILRDEERIKKRKIQKNRAANLQRTLQPPKRPTPSAASEVPKKKYKKIKVDPSARRTSSRMHTVLMAQSTETRLQEAKPRRKYTVSASANRQKGTMTQQQRFEEAAKTEAQNLSSLRNYVHLEEQRRLRLKRNAAKHRQLREPILKFISKTISTEDGREASNYYVAPLEHPLCHSAPPLQMPQHRAVECVITGKPAIYLDPVTQLPISNVQAFQQVREVYNQRYSWSAMLNLFH
What is the function of this protein?
Participates in the catalytic exchange of histone H2A for the H2A variant pht1, an euchromatin-specific factor, leading to chromatin remodeling and changes in transcription of targeted genes.
What are the official names of this protein?
SWR complex protein 2.
What is the protein family that this protein belongs to?
Belongs to the VPS72/YL1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DHB4_HUMAN
Sequence: MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL
What is the function of this protein?
Bifunctional enzyme acting on the peroxisomal fatty acid beta-oxidation pathway.  Catalyzes two of the four reactions in fatty acid degradation: hydration of 2-enoyl-CoA (trans-2-enoyl-CoA) to produce (3R)-3-hydroxyacyl-CoA, and dehydrogenation of (3R)-3-hydroxyacyl-CoA to produce 3-ketoacyl-CoA (3-oxoacyl-CoA), which is further metabolized by SCPx.  Can use straight-chain and branched-chain fatty acids, as well as bile acid intermediates as substrates.
What are the official names of this protein?
Peroxisomal multifunctional enzyme type 2, MFE-2, 17-beta-hydroxysteroid dehydrogenase 4, 17-beta-HSD 4, D-bifunctional protein, DBP, Multifunctional protein 2, MFP-2, Short chain dehydrogenase/reductase family 8C member 1.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: YGR8_SCHPO
Sequence: MASEFSGQIQELLSRIPPVTRYILLGTAATTILTLCQLLSPSMLVLHYPLVVRQKQWYRLFTNYLYAGTGFDFIMNIYFFYQYSTYLENFVFARNAKKYIIYLVKVALLIDAFSLISGLGSALNQSLAAAIAYNWSLFNSFSKIQFLFGFHVQGKYLPYVLLGFSFLTGGLPSLVVLGFGIISAMIVNFFDSIHTPVVHRSNSPKLNSQKVSGTFIGKGKKLGT
What are the official names of this protein?
Uncharacterized derlin-like protein C365.08c.
What is the protein family that this protein belongs to?
Belongs to the derlin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: LIPB_ECO27
Sequence: MYQDKILVRQLGLQPYEPISQAMHEFTDTRDDSTLDEIWLVEHYPVFTQGQAGKAEHILMPGDIPVIQSDRGGQVTYHGPGQQVMYVLLNLKRRKLGVRELVTLLEQTVVNTLAELGIEAHPRADAPGVYVGEKKICSLGLRIRRGCSFHGLALNVNMDLSPFLRINPCGYAGMEMAKISQWKPEATTNNIAPRLLENILALLNNPDFEYITA
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.