PharMolix/UniProtQA huggingface dataset:
Protein: G2OX4_ARATH
Sequence: MVKGSQKIVAVDQDIPIIDMSQERSQVSMQIVKACESLGFFKVINHGVDQTTISRMEQESINFFAKPAHEKKSVRPVNQPFRYGFRDIGLNGDSGEVEYLLFHTNDPAFRSQLSFSSAVNCYIEAVKQLAREILDLTAEGLHVPPHSFSRLISSVDSDSVLRVNHYPPSDQFFGEANLSDQSVSLTRVGFGEHTDPQILTVLRSNGVGGLQVSNSDGMWVSVSPDPSAFCVNVGDLLQVMTNGRFISVRHRALTYGEESRLSTAYFAGPPLQAKIGPLSAMVMTMNQPRLYQTFTWGEYKKRAYSLRLEDSRLDMFRTCKD
What is the function of this protein?
Catalyzes the 2-beta-hydroxylation of several biologically active gibberellins, leading to the homeostatic regulation of their endogenous level.  Catabolism of gibberellins (GAs) plays a central role in plant development.  Converts GA9/GA20 to GA51/GA29 and GA4/GA1 to GA34/GA8.
What are the official names of this protein?
Gibberellin 2-beta-dioxygenase 4, GA 2-oxidase 4, Gibberellin 2-beta-hydroxylase 4, Gibberellin 2-oxidase 4.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family. GA2OX subfamily.
Protein: FUR_NEIMC
Sequence: MEKFSNIAQLKDSGLKVTGPRLKILDLFETHAEEHLSAEDVYRILLEEGVEIGVATIYRVLTQFEQAGILQRHHFETGKAVYELDKGDHHDHIVCVKCGEVTEFHNPEIEALQDKIAEENGYRIVDHALYMYGVCSDCQAKGKR
What is the function of this protein?
Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.  Regulates the expression of the fbp protein.
What are the official names of this protein?
Ferric uptake regulation protein, Ferric uptake regulator.
What is the protein family that this protein belongs to?
Belongs to the Fur family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYA_SHIDS
Sequence: MSKSTAEIRQAFLDFFHSKGHQVVASSSLVPHNDPTLLFTNAGMNQFKDVFLGLDKRNYSRATTSQRCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKHDAIQFAWELLTSEKWFALPKERLWVTVYESDDEAYEIWEKEVGIPRERIIRIGDNKGAPYASDNFWQMGDTGPCGPCTEIFYDHGDHIWGGPPGSPEEDGDRYIEIWNIVFMQFNRQADGTMEPLPKPSVDTGMGLERIAAVLQHVNSNYDIDLFRTLIQAVAKVTGATDLSNKSLRVIADHIRSCAFLIADGVMPSNENRGYVLRRIIRRAVRHGNMLGAKETFFYKLVGPLIDVMGSAGEDLKRQQAQVEQVLKTEEEQFARTLERGLALLDEELAKLSGDTLDGETAFRLYDTYGFPVDLTADVCRERNIKVDEAGFEAAMEEQRRRAREASGFGADYNAMIRVDSASEFKGYDHLELNGKVTALFVDGKAVDAINAGQDAVVVLDQTPFYAESGGQVGDKGELKGANFSFVVEDTQKYGQAIGHIGKLAAGSLKVGDAVQADVDEARRARIRLNHSATHLMHAALRQVLGTHVSQKGSLVNDKVLRFDFSHNEAMKPEEIRAVEDLVNAQIRRNLPIETNIMDLEAAKAKGAMALFGEKYDERVRVLSMGDFSTELCGGTHASRTGDIGLFRIISESGTAAGVRRIEAVTGEGAIATVHADSDRLSEVAHLLKGDSNNLADKVRSVLERTRQLEKELQQLKEQAAAQESANLSSKAIDVNGVKLLVSELSGVEPKMLRTMVDDLKNQLGSTIIVLATVAEGKVSLIAGVSKDVTDRVKAGELIGMVAQQVGGKGGGRPDMAQAGGTDAAALPAALASVKGWVSAKLQ
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YHJY_ECOLI
Sequence: MIIKKSGGRWQLSLLASVVISAFFLNTAYAWQQEYIVDTQPGLSTERYTWDSDHQPDYNDILSQRIQSSQRALGLEVNLAEETPVDVTSSMSMGWNFPLYEQVTTGPVAALHYDGTTTSMYNEFGDSTTTLTDPLWHASVSTLGWRVDSRLGDLRPWAQISYNQQFGENIWKAQSGLSRMTATNQNGNWLDVTVGADMLLNQNIAAYAALTQAENTTNNSDYLYTMGVSARF
What are the official names of this protein?
Uncharacterized protein YhjY.
Protein: URE2_DEBHA
Sequence: MTNNNSNSNNNQTISNLSAGLKSVNLADQQQNEVNLNLLQQQLQNEATTQQSQSRISQFFQNQPTEGYTLFSHRSAPNGFKVAIILSELNLPFNTIFLDFNNGEQRAPEFVTINPNARVPALIDHFNENTSIWESGAIILYLVSKYLKDNGECALWSDNLIEQSQISSWLFFQTSGHAPMIGQALHFRYFHSCPVPSAVERYTDEVRRVYGVIEMALAERREALIMDLDVENAAAYSAGTTPLSQSRYFDYPVWLVGDRATVADLSFVPWNNVVDRIGINLKVEFPEVYKWTKYMMRRPAVIRALRGD
What is the function of this protein?
Plays an important role in the cellular response to the nitrogen source.  URE2 gene plays a major part in the repression of GLN1 and GDH2 genes by glutamine, and is required for the inactivation of glutamine synthetase.  URE2 gene product may catalytically inactivate GLN3 in response to an increase in the intracellular concentration of glutamine (By similarity).
What are the official names of this protein?
Protein URE2.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily.
Protein: CSPL1_PTEAA
Sequence: MDGSAHLRDPPGPAVLRWRLEDMHIIPGTSGSLALRICQFSAAIVSFSVMISAANFSSVTAFCFLVAAMVLQCMWSLSVATIEGYAMLVGRSLRDSPLLSLFAVGDWVTAVITFAGACASAGIAVLVGRDIHRGCDVNFCGRYAAAAGMAFLSWLLISTSFLFTFWLLATR
What are the official names of this protein?
CASP-like protein 5A2, PaCASPL5A2.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UMUD_SALTY
Sequence: MEFFRPTELREIIPLPFFSYLVPCGFPSPAADYIEQRIDLNELLVSHPSSTYFVKASGDSMIEAGISDGDLLVVDSSRNADHGDIVIAAIEGEFTVKRLQLRPTVQLIPMNGAYRPIPVGSEDTLDIFGVVTFIIKAVS
What is the function of this protein?
Involved in UV protection and mutation.  Essential for induced (or SOS) mutagenesis.  May modify the DNA replication machinery to allow bypass synthesis across a damaged template.
What are the official names of this protein?
Protein UmuD.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: NUOH_DINSH
Sequence: MADFFSTGPGIAVLIIAQCLAVLGFVMVSLLFLVYGDRKIWAAVQMRRGPNVVGAFGLLQTVADALKYVVKEVVVPAGADKPVFMLAPMTSFVLAMIAWAVIPFNDGWVLADINVAILYVFAVSSLEVYGVIMGGWASNSKYPFLGSLRSAAQMISYEVSIGLIIIGVILSTGSMNFSAIVAAQDGDFGFFSWYWLPHLPMVFLFFISALAETNRPPFDLPEAESELVAGYQVEYSSTPFLLFMAGEYIAIFLMCALITLLFFGGWLSPIPFLPDGPIWMVGKMAFFFFLFAMVKAIVPRYRYDQLMRLGWKVFLPFSLAWVVFVAFAAQFELFGGAYARWAIGG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PR1F1_ARATH
Sequence: MTTYGTNQKSSNDLAPKLEYITRGINQHKRSGLATRRPWKQMLDLGSFNFPRKLATVITRIRANTVYFQTNYTIVVLFSVFLSLIWNPFSLLVLLALLGAWLFLYFLRDEPLTVFDREIDHRIVLIIMSVITLSILFLTDAKLNIAVAIVAGALAVLSHAAVRKTEDLFQTDEETSLLNP
What is the function of this protein?
May be involved in both secretory and endocytic intracellular trafficking in the endosomal/prevacuolar compartments.
What are the official names of this protein?
PRA1 family protein F1, AtPRA1.F1.
What is the protein family that this protein belongs to?
Belongs to the PRA1 family.
What are the subcellular locations of this protein?
Endosome membrane; Multi-pass membrane protein.
Protein: AGRL2_RAT
Sequence: MVSSGCRMRSLWFIMIISFSPNTEGFSRAALPFGLVRRELSCEGYSIDLRCPGSDVIMIESANYGRTDDKICDADPFQMENTDCYLPDAFKIMTQRCNNRTQCVVVTGSDVFPDPCPGTYKYLEVQYECVPYMEQKVFVCPGTLKAIVDSPSIYEAEQKAGAWCKDPLQAADKIYFMPWTPYRTDTLIEYASLEDFQNSRQTTTYKLPNRVDGTGFVVYDGAVFFNKERTRNIVKFDLRTRIKSGEAIINYANYHDTSPYRWGGKTDIDLAVDENGLWVIYATEQNNGMIVISQLNPYTLRFEATWETTYDKRAASNAFMICGVLYVVRSVYQDNESEAGKNVIDYIYNTRLSRGEHVDVPFPNQYQYIAAVDYNPRDNQLYVWNNNFILRYSLEFGPPDPAQVPTTAVTITSSAELFKTTVSTTSSTSQRGPVSSTVAGPQEGSRGTKPPPAVSTTKIPPVTNIFPLPERFCEALEMKGIKWPQTQRGMMVERPCPKGTRGTASYLCMASTGTWNPKGPDLSNCTSHWVNQLAQKIRSGENAASLANELAKHTKGTVFAGDVSSSVRLMEQLVDILDAQLQELKPSEKDSAGRSYNKLQKREKTCRAYLKAIVDTVDNLLRAETLDCWKHMNSSEQAHTATMLLDTLEEGAFVLADNLLEPTRVSMPTDNIVLEVAVLSTEGQVQDFTFHLGFKGAFSSIQLSANTVKQNSRNGLAKVVFIIYRSLGPFLSTENATVKLGADLLGRNSTIAVNSHVLSVSINKESSRVYLTDPVLFSMPHIDSDNYFNANCSFWNYSERTMMGYWSTQGCKLVDTNKTRTTCACSHLTNFAILMAHREIVYKDGVHKLLLTVITWVGIVVSLVCLAICIFTFCFFRGLQSDRNTIHKNLCINLFIAEFIFLIGIDKTQYTIACPVFAGLLHFFFLAAFSWMCLEGVQLYLMLVEVFESEYSRKKYYYVAGYLFPATVVGVSAAIDSKSYGTLEACWLHVDNYFIWSFIGPVTFIILLNIIFLVITLCKMVKHSNTLKPDSSRLENINNYRVCDGYYNTDLPGYEDNKPFIKSWVLGAFALLCLLGLTWSFGLLFVNEETVVMAYLFTAFNAFQGLFIFIFHCALQKKVRKEYAKCFRHWYCCGGLPTESPHSSVKASTSRTSARYSSGTQSRIRRMWNDTVRKQSESSFISGDINSTSTLNQGMTGNYLLTNPLLRPHGTNNPYNTLLAETVVCNAPSAPVFNSPGHSLNNTRDTSAMDTLPLNGNFNNSYSLRKADYHDGVQVVDCGLSLNDTAFEKMIISELVHNNLRGSNKTHNLELKLPVKPVIGGSSSEDDAIVADASSLMHGDNPGLEFRHKELEAPLIPQRTHSLLYQPQKKVKPEATDSYVSQLTAEADEHLQSPNRDSLYTSMPNLRDSPYPESSPDMAEDLSPSRRSENEDIYYKSMPNLGAGRQLQMCYQISRGNSDGYIIPINKEGCIPEGDVREGQMQLVTSL
What is the function of this protein?
Calcium-independent receptor of low affinity for alpha-latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells.  Receptor probably implicated in the regulation of exocytosis.
What are the official names of this protein?
Adhesion G protein-coupled receptor L2, Calcium-independent alpha-latrotoxin receptor 2, CIRL-2, Latrophilin-2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HSS_RHILO
Sequence: MLDKMANENWPVYGEITGPVVMIGFGSIGRGTLPLIERHFKFDKSRMTVLDPRDTDRKLLDERGIAFVQEAVTENNYKKLLTPLLTNGGGQGFCVNLSVDTGSVDLMRLCRKLGVLYIDTVVEPWLGFYFDAKADNASRTNYALREAMIKEKHDKPGGATVVSTCGANPGMVSWFVKQALVNLATDLGLEFSEPAQEDREGWAKLMKKAGVKGIHIAERDTQRTKKPKPMDVFWNTWSVEGFISEGLQPAELGWGTHEKWMPKNGKKHKHGSKAAIYLEQPGANTRVRSWCPTPGAQYGLLVTHNEAISIADFFTVRSKKGKVQYRPTCHYAYHPSNDAMLSLDEMFGAAGKPQPVHHVLDENELVDGVDELGVLLYGHDKNAYWYGSQLSLAEARKLAPYQNATGMQVTSAVLAGMVWALENPDAGIVEADEMDYKRCLDVQSPYLGPVKGYYTDWTPLDRRPGLFPEDLDRSDPWQFRNILVR
What is the function of this protein?
Involved in the NAD(+)-dependent synthesis of the polyamine homospermidine from putrescine.
What are the official names of this protein?
Homospermidine synthase, HSS.
What is the protein family that this protein belongs to?
Belongs to the saccharopine dehydrogenase family.
Protein: LPXC_CITK8
Sequence: MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDLNPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVDAPEIPIMDGSAAPFVYLLLDAGIDELNCAKKFVRIKETVRVEDGDKWAEFKPYNGFTLDFTIDFNHPAIDSSSQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVVDDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVLAKQEAWEYVTFQDDAELPLAFKAPSTVLA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: Y1821_LISW6
Sequence: MFEKTNRMNLLFDFYQELLTTKQKAYVSFYYLDDYSLGEIAEEFEVSRQAIYDNIKRTEESLEKYEEKLGMLKKYQQREKLFSELEAQLTKKNFLDEQVKDTLEQLKNID
What is the function of this protein?
Might take part in the signal recognition particle (SRP) pathway.  This is inferred from the conservation of its genetic proximity to ftsY/ffh.  May be a regulatory protein.
What are the official names of this protein?
UPF0122 protein lwe1821.
What is the protein family that this protein belongs to?
Belongs to the UPF0122 family.
Protein: RT12_BOVIN
Sequence: MSWSGLLRGLSMSLNYGLALAPRPWGTRPMATLNQLHRRGPPKFPPSKPGPTEGRPQLKGVVLRTFIRKPKKPNSANRKCCRVRLSTGREAVCFIPGEGHNLQEHHVVLVQGGRTQDLPGVKLKVVRGKYDCGHVQKKK
What are the official names of this protein?
28S ribosomal protein S12, mitochondrial, MRP-S12, S12mt.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: KDSA_BRUC2
Sequence: MVTANSTVKVGNVTFSNSAPLALIAGPCQMETRDHAFEMAGHLKEMTDKLGIGLVYKSSFDKANRTSLKAARGIGLEKALEVFSDLKKEYGFPVLTDIHTEEQCAAVAPVVDVLQIPAFLCRQTDLLIAAARTGRVVNVKKGQFLAPWDMKNVLAKITESGNPNVLATERGVSFGYNTLVSDMRALPIMAGLGAPVIFDATHSVQQPGGQGGSTGGQREFVETLARAAVAVGVAGLFIETHEDPDNAPSDGPNMVPIDKMPALLEKLMAFDRIAKAL
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIKC_STAAC
Sequence: MHKIFSKNNLIFFVFVAFIFVVIVLQFFVSSENATKVNLSQTFEPISWLHLLGTDDYGRDLFTRIIIGARSTLFVTVLTLIAIVVIGVTLGLFAGYKKGWIERLVLRFIDVGLSIPEFIIMIALASFFQPSLWNLVISITLIKWMNYTRLTRSIVNSEMNKPYIKMAQLFHVPTRTILIRHLTPKIIPAIIVLMVVDFGKIILYISSLSFIGLGAQPPTPEWGAMLQQGRDFISSHPIMLIAPASVIAITILIFNLTGDALRDRLLKQRGEYDESH
What is the function of this protein?
Part of the ABC transporter complex NikABCDE (Opp2) involved in nickel import.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Nickel import system permease protein NikC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATP6_RICPR
Sequence: MTHSPLIQFNIKKLIDIKMFGFDVSFTNSSIYMLLATTLSLTYLYLAFYNRKLIPSRLQVSAEIVYNLVADMLNQNIGIKGRKFIPLVFSLFIFILFCNLLGMTPYSFTATSHIIVTFTLALLIFLTVTIVGFIKHGVSFLTLFLPHGTPVWLAPLMIVIELFTYLARPVSLSLRLAANMMAGHVLLKVIASFTVSLMIYLKFLPIPLMVILIGFEIFIAILQAYIFTILSCMYLNDAINLH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1519_ALKCK
Sequence: MSNAYDKAHELKEALAETQEFKSLYDLHRQIDADDIAKKMLENFRKLQLDLQQKQMQGVQISEEEAQQAQQQFELVSQHELISKLMDAEQRLSVIITDLNKIITEPLERIYGEPPQEQ
What are the official names of this protein?
UPF0342 protein ABC1519.
What is the protein family that this protein belongs to?
Belongs to the UPF0342 family.
Protein: RL16_LACE2
Sequence: MLLPKRVKHRRQFRGSMAGKATRGNKITNGEFGIVATEPCWIKSNQIEAARVAMTRYIKRGGKVFIKIFPDKPVTGKPIGVRMGKGKGNLECWVAVVKPGRVMFEISGVAEETAREALRLATHKLPCKCKIVSRADLEGGDNSEN
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: ACPS_RENSM
Sequence: MIIGIGIDVVDVERFRRQLERTPGLLDRLFVPAERSLNTRSLAARFAAKEAVAKALGAPAGMNWQDCWIGLDVNGPTVQTKNTVAAVAEAQGVKRWHLSMSHDGGISTAFVIAES
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MESD_MOUSE
Sequence: MAASRWLRAVLLFLCASDLLLLPPPNAYAADTPGEATPPPRKKKDIRDYNDADMARLLEQWEKDDDIEEGDLPEHKRPSAPIDFSKLDPGKPESILKMTKKGKTLMMFVTVSGNPTEKETEEITSLWQGSLFNANYDVQRFIVGSDRAIFMLRDGSYAWEIKDFLVSQDRCAEVTLEGQMYPGKGGGSKEKNKTKPEKAKKKEGDPKPRASKEDNRAGSRREDL
What is the function of this protein?
Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs) (PubMed:31564437).  Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane.  Essential for specification of embryonic polarity and mesoderm induction (PubMed:12581525, PubMed:21397183).  Plays an essential role in neuromuscular junction (NMJ) formation by promoting cell-surface expression of LRP4 (PubMed:24140340).  May regulate phagocytosis of apoptotic retinal pigment epithelium (RPE) cells.
What are the official names of this protein?
LRP chaperone MESD, LDLR chaperone MESD, Mesoderm development candidate 2, Mesoderm development protein.
What is the protein family that this protein belongs to?
Belongs to the MESD family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Note=Released from apoptotic cells and shed photoreceptor outer segments (PubMed:27184668).
Protein: SFSA_CALS4
Sequence: MIIKNPIIKGKFIERLNRFEAYVEIDGIKTLVHVPNTGRLKEILVKGADVLLEVREKKGRKTPYELAFAYKGKRLISIDSQVPNKVFLESIKKGIVEEFRGYELVEKEKSFGNSKFDIKLTNGKEICYIEVKGVTLEVDGVAKFPDAPTERGRKHLKELIKVKEEGMRAAVVFLIQMDDIKYFTPNDEQDPQFGQFLREAFTKGVEVYAYTCDVGENFINLKNRVQVVL
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: TRMA_SHEB2
Sequence: MNLAAMDPQTYDTQLEHKRIKLEQAFAQFETPSVEVFASEPANYRMRAEFRMWHDGDDLYYYMFDKVLNEKVRCDQYLPASVLINQMMSALIAELKPNPSLRHKLFQVDFLSTLSGEILVSLLYHRQLDDQWRADATALKAKLSSQFNVNIIGRARKQKIDLDKDFVVESLQVNDKTFLYKQIENSFTQPNAKVSVKMLEWAIDATQNSQGDLLELYCGNGNFSIALAQNFNRVLATELAKPSVDAAQYNIEVNGIENLQIIRMSAEDFSDAMAKKRSFRRLEGIDLDSYVCNTIFVDPPRAGIDPDTLALVQGYERILYISCNPETLKDNLQQLNETHKVTRFALFDQFPYTDHMETGVLLERR
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: FMT_ECOL6
Sequence: MSESLRIIFAGTPDFAARHLDALLSSGHNIVGVFTQPDRPAGRGKKLMPSPVKVLAEDKGLPVFQPVSLRPQENQQRVADLQADVMVVVAYGLILPKAVLEMPRLGCINVHGSLLPRWRGAAPIQRSLWAGDAETGVTIMQMDVGLDTGDMLYKLSCPITAEDTSGTLYDKLAELGPQGLITTLKQLADGTAKPEVQDETLVTYAEKLSKEEARIDWSLSAAQLERCIRAFNPWPMSWLEIEGQPVKVWKASVIDTTTKAAPGTILEANKQGIQVATGDGILNLLSMQPAGKKAMSVQDLLNSRREWFVPGNRLA
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: T2E5_ECOLX
Sequence: MSLRSDLINALYDENQKYDVCGIISAEGKIYPLGSDTKVLSTIFELFSRPIINKIAEKHGYIVEEPKQQNHYPDFTLYKPSEPNKKIAIDIKTTYTNKENEKIKFTLGGYTSFIRNNTKNIVYPFDQYIAHWIIGYVYTRVATRKSSLKTYNINELNEIPKPYKGVKVFLQDKWVIAGDLAGSGNTTNIGSIHAHYKDFVEGKGIFDSEDEFLDYWRNYERTSQLRNDKYNNISEYRNWIYRGRK
What is the function of this protein?
A P subtype restriction enzyme that recognizes the double-stranded sequence 5'-GATATC-3' and cleaves after T-3.
What are the official names of this protein?
Type II restriction enzyme EcoRV, R.EcoRV, Endonuclease EcoRV, Type-2 restriction enzyme EcoRV.
Protein: UST_MOUSE
Sequence: MKKKQQQHPGGGTDPWPHGAPVGGAPPCLGSCKRRIPLLPFLRFSLRDYGFCMATLLVFCLGSLFYQLSGGPPRFLLDLRQYLGNSTYLDDHGPPPSKVLPFPSQVVYNRVGKCGSRTVVLLLRILSEKHGFNLVTSDIHNKTRLTKNEQMELIKNISTAEQPYLFTRHVHFLNFSRFGGDQPVYINIIRDPVSRFLSNYFFRRFGDWRGEQNHMIRTPSMRQEERYLDINECILENYPECSNPRLFYIIPYFCGQHPRCREPGEWALERAKLNVNENFLLVGILEELEDVLLLLERFLPHYFKGVLSIYKDPEHRKLGNMTVTVRKTVPSPEAVQILYQRMRYEYEFYHYVREQFHLLKRKLGLKSRVSGPPVRPQFFIPTPLETEEPIDDEEQDDEKWLEDIYKR
What is the function of this protein?
Sulfotransferase that catalyzes the transfer of sulfate to the position 2 of uronyl residues.  Has mainly activity toward iduronyl residues in dermatan sulfate, and weaker activity toward glucuronyl residues of chondroitin sulfate.  Has no activity toward desulfated N-resulfated heparin (By similarity).
What are the official names of this protein?
Uronyl 2-sulfotransferase.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 3 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: DCP2_YEAST
Sequence: MSLPLRHALENVTSVDRILEDLLVRFIINCPNEDLSSVERELFHFEEASWFYTDFIKLMNPTLPSLKIKSFAQLIIKLCPLVWKWDIRVDEALQQFSKYKKSIPVRGAAIFNENLSKILLVQGTESDSWSFPRGKISKDENDIDCCIREVKEEIGFDLTDYIDDNQFIERNIQGKNYKIFLISGVSEVFNFKPQVRNEIDKIEWFDFKKISKTMYKSNIKYYLINSMMRPLSMWLRHQRQIKNEDQLKSYAEEQLKLLLGITKEEQIDPGRELLNMLHTAVQANSNNNAVSNGQVPSSQELQHLKEQSGEHNQQKDQQSSFSSQQQPSIFPSLSEPFANNKNVIPPTMPMANVFMSNPQLFATMNGQPFAPFPFMLPLTNNSNSANPIPTPVPPNFNAPPNPMAFGVPNMHNLSGPAVSQPFSLPPAPLPRDSGYSSSSPGQLLDILNSKKPDSNVQSSKKPKLKILQRGTDLNSIKQNNNDETAHSNSQALLDLLKKPTSSQKIHASKPDTSFLPNDSVSGIQDAEYEDFESSSDEEVETARDERNSLNVDIGVNVMPSEKDSRRSQKEKPRNDASKTNLNASAESNSVEWGPGKSSPSTQSKQNSSVGMQNKYRQEIHIGDSDAYEVFESSSDEEDGKKLEELEQTQDNSKLISQDILKENNFQDGEVPHRDMPTESNKSINETVGLSSTTNTVKKVPKVKILKRGETFASLANDKKAFDSSSNVSSSKDLLQMLRNPISSTVSSNQQSPKSQHLSGDEEIMMMLKRNSVSKPQNSEENASTSSINDANASELLGMLKQKEKDITAPKQPYNVDSYSQKNSAKGLLNILKKNDSTGYPRTEGGPSSEMSTSMKRNDATNNQELDKNSTELLNYLKPKPLNDGYENISNKDSSHELLNILHGNKNSSAFNNNVYATDGYSLASDNNENSSNKLLNMLQNRSSAINEPNFDVRSNGTSGSNELLSILHRK
What is the function of this protein?
Catalytic component of the decapping complex necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay (PubMed:10508173, PubMed:11139489, PubMed:11741542).  Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP (PubMed:12554866).  Decapping is the major pathway of mRNA degradation in yeast and occurs through deadenylation, decapping and subsequent 5' to 3' exonucleolytic decay of the transcript body (PubMed:10508173, PubMed:11139489, PubMed:11741542).  Blocks autophagy in nutrient-rich conditions by repressing the expression of ATG-related genes through degradation of their transcripts (PubMed:19779198).
What are the official names of this protein?
m7GpppN-mRNA hydrolase, Protein PSU1, mRNA-decapping enzyme subunit 2.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. DCP2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, P-body.
Protein: RFCL_PYRHO
Sequence: MPDVPWIEKYRPRKLSEIVNQEQALEKVRAWIESWLHGNPPKKKALLLAGPPGSGKTTTVYALAHEYNFEVIELNASDERTYNKIARYVQAAYTMDIMGKRRKIIFLDEADNIEPSGAPEIAKLIDKARNPIIMAANHYWEVPKEIRDRAELVEYKRLNQRDVISALVRILKREGITVPKEILTEIAKRSSGDLRAAINDLQTIVAGGYEDAKYVLAYRDVEKTVFQSLGMVFSSDNAKRAKLALMNLDMSPDEFLLWVDENIPHMYLKPEEMARAYEAISRADIYLGRAQRTGNYSLWKYAIDMMTAGVAVAGTKKKGFAKFYPPNTLKMLAESKEERSIRDSIIKKIMKEMHMSKLEALETMKILRTIFENNLDLAAHFTVFLELTEKEVEFLAGKEKAGTIWGKTLSIRRRIKETEKIEEKAVEEKVEEEEAEEEEEEERKEEEKPKAEKKKGKQVTLFDFIKKN
What is the function of this protein?
Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.
What are the official names of this protein?
Replication factor C large subunit, RFC large subunit, Clamp loader large subunit.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family. RfcL subfamily.