PharMolix/UniProtQA huggingface dataset:
Protein: FBX5_XENTR
Sequence: MMCGFTSNQSPKKLSSKKLSATNVHLEISPVKCDSPCKGYENVQASYLDTANCTTVTRGADIKDDLPLHNKENLLHRFGDLETHSDEEYSGLQDSGYSSILQNDSPCQDETDNNVSDIQLRETPKNFVQFQKPLHTLSTKNLPALRFEEAMCSTLKKMRKTSKKIDWNAVDDVVCGGNYGLENLIGKNMGLERFDILAELFHRDFKHLLTKILRHLSAMDLINVISVSTTWRKILQKDNSAYNSYKLGCKELCEKKAKVSAHTATRDESLCRVPLASVQKVAASSLCTSKKQSKNRGLSNNRHAEFIEVAQTLKNDQCLKVCVDCSSPAKYDPYLHRATCTRESCKFDFCTLCSCKYHGSKCCQTSKPRSYRVPSEPLPGSKKSKQNLRRL
What is the function of this protein?
Regulates progression through early mitosis by inhibiting the anaphase promoting complex/cyclosome (APC).  Binds to the APC activators cdc20 to prevent APC activation.  Can also bind directly to the APC to inhibit substrate-binding.  Required to arrest unfertilized eggs at metaphase of meiosis II, by preventing their release from metaphase of meiosis II, through inhibition of APC-dependent cyclin B destruction leading to stabilization of cyclin B-cdk1 complex activity.
What are the official names of this protein?
F-box only protein 5.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=In interphase, localizes in a punctate manner in the nucleus and cytoplasm with some perinuclear concentration. In mitotic cells, localizes throughout the cell, particularly at the spindle. At metaphase, localized at mitotic centrosomes. Decreases centrosome localization as cells progressed through telophase.
Protein: RL1_LYSSC
Sequence: MAKKGKKLQDAAKLIDRNSLYSAQEAIELAQKTSTVNFDATVEVAFRLGIDTRKNDQQIRGAVVLPNGTGKTQRVLVFAKGEKLKEAEAAGADYVGDAEYIQKIQQGWFDFDVIVATPDMMGEVGKLGRVLGPKGLMPNPKTGTVTFDVTKAIEEIKAGKVEYRADKAGIIHAPIGKVSFSAAKLVENFLAVFDVVQKAKPAAAKGTYMKSVNITTTMGPAVKIDAANVVVK
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: ZN101_HUMAN
Sequence: MDSVAFEDVAVNFTQEEWALLSPSQKNLYRDVTLETFRNLASVGIQWKDQDIENLYQNLGIKLRSLVERLCGRKEGNEHRETFSQIPDCHLNKKSQTGVKPCKCSVCGKVFLRHSFLDRHMRAHAGHKRSECGGEWRETPRKQKQHGKASISPSSGARRTVTPTRKRPYECKVCGKAFNSPNLFQIHQRTHTGKRSYKCREIVRAFTVSSFFRKHGKMHTGEKRYECKYCGKPIDYPSLFQIHVRTHTGEKPYKCKQCGKAFISAGYLRTHEIRSHALEKSHQCQECGKKLSCSSSLHRHERTHSGGKLYECQKCAKVFRCPTSLQAHERAHTGERPYECNKCGKTFNYPSCFRRHKKTHSGEKPYECTRCGKAFGWCSSLRRHEMTHTGEKPFDCKQCGKVFTFSNYLRLHERTHLAGRSQCFGRRQGDHLSPGV
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 101, Zinc finger protein HZF12.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HBA_CHICK
Sequence: MVLSAADKNNVKGIFTKIAGHAEEYGAETLERMFTTYPPTKTYFPHFDLSHGSAQIKGHGKKVVAALIEAANHIDDIAGTLSKLSDLHAHKLRVDPVNFKLLGQCFLVVVAIHHPAALTPEVHASLDKFLCAVGTVLTAKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-A, Alpha-A-globin, Hemoglobin alpha-A chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: LMOD2_MOUSE
Sequence: MSTFGYRRGLSKYESIDEDELLASLSPEELKELERELEDIEPDRNLPVGLRQKSLTEKTPTGNFSREALMAYWEKESQKLLEKERLGECGKVAEEDKEESEEELIFTESNSEVSEEVCTEDEEESQEEEEDSEEEEDSEEEEETTEATKHINGTVSYNSVNTDNSKPKTFKSQIENINLTNGNSGRTQRNSESPAAIHPCGNPTVIEDALEKIRNNDPDTTEVNLNNIENITTQTLSRFAEALKENTVVKTFSLANTHADDAAAIAIADMLKVNEHITSVNVESNFITGKGILAIMRALQHNTVLTELRFHNQRHIMGSQVEMEIVKLLKENTTLLRLGYHFELPGPRMSMTSILTRNMDKQRQKRMQEQKQQEGHDGGAALRTKVWQRGTPGSSPYASPRQSPWSSPKVSKKVHTGRSRPPSPVAPPPPPPPPPLPPHMLPPPPPPPAPPLPEKKLITRNIAEVIKQQESAQRALQNGQRKKKGKKVKKQPNNILKEIKNSLRSVQEKKMEDSSRPSTPQRSVHENLMEAIRGSSIRQLRRVEVPEALR
What is the function of this protein?
Mediates nucleation of actin filaments and thereby promotes actin polymerization (By similarity).  Plays a role in the regulation of actin filament length (PubMed:26487682).  Required for normal sarcomere organization in the heart, and for normal heart function (PubMed:26487682, PubMed:27274810).
What are the official names of this protein?
Leiomodin-2, Cardiac leiomodin, C-LMOD, Leiomodin.
What is the protein family that this protein belongs to?
Belongs to the tropomodulin family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere. Cytoplasm, myofibril. Cytoplasm, myofibril, sarcomere, M line. Cytoplasm, cytoskeleton. Note=Colocalizes with actin filaments in sarcomeres. Detected close to the M line.
Protein: IOVO_ANSIN
Sequence: VATVDCSDYPKPACTVEYMPLCGSDNKTYDNKCNFCNAVVDSNGTLTLSHFGKC
What are the official names of this protein?
Ovomucoid.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1109_DESHY
Sequence: MFMERQDRYYQTYLNILKEELVAAMGCTEPIAIAYGAAKAREVLGAVPHKVVLEVSSNIIKNVKSVVVPNTDGLKGIEAATAAGIIAGRSDKILEVIAEVCQAEKQQIKTYLSETDIEVKLADSQIIFDIMITMFHQDSYVKLRIADYHTHIVHIEKNGEIIFGTGDLDAGISSLTDRKLLSVSKIIEFADSVRIEDVKELLDKQIEYNSAIARAGMEGNYGANVGRVLLKTYGNDVKIRAKAMAAAGSDARMSGCELPVIINSGSGNQGMTASLPVIEYAAELQSGEEKLYRALVVSNLITLHLKTGIGRLSAFCGVICAGCGSGAGIAYLHGGGYDEIAHTIVNAAAIVSGIVCDGAKPSCAGKIAAAVDAGILGYLMYKEGQQFRGGDGIVAKGIENTIANIGYLGKVGMKETDKEIINIMLNQCSS
What are the official names of this protein?
UPF0597 protein DSY1109.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.
Protein: LMAN2_HUMAN
Sequence: MAAEGWIWRWGWGRRCLGRPGLLGPGPGPTTPLFLLLLLGSVTADITDGNSEHLKREHSLIKPYQGVGSSSMPLWDFQGSTMLTSQYVRLTPDERSKEGSIWNHQPCFLKDWEMHVHFKVHGTGKKNLHGDGIALWYTRDRLVPGPVFGSKDNFHGLAIFLDTYPNDETTERVFPYISVMVNNGSLSYDHSKDGRWTELAGCTADFRNRDHDTFLAVRYSRGRLTVMTDLEDKNEWKNCIDITGVRLPTGYYFGASAGTGDLSDNHDIISMKLFQLMVEHTPDEESIDWTKIEPSVNFLKSPKDNVDDPTGNFRSGPLTGWRVFLLLLCALLGIVVCAVVGAVVFQKRQERNKRFY
What is the function of this protein?
Plays a role as an intracellular lectin in the early secretory pathway.  Interacts with N-acetyl-D-galactosamine and high-mannose type glycans and may also bind to O-linked glycans.  Involved in the transport and sorting of glycoproteins carrying high mannose-type glycans (By similarity).
What are the official names of this protein?
Vesicular integral-membrane protein VIP36, Glycoprotein GP36b, Lectin mannose-binding 2, Vesicular integral-membrane protein 36, VIP36.
Protein: RNPA_CAMJD
Sequence: MKNFDKFSTNEEFSSVYKVGKKWHCEGVIIFYLNSYEKKIAVVASKKVGKAVVRNRSKRILRALFAKFERYLQDGKYIFVAKNEITELSFSRLEKNLKWGLKKLECFK
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: C2C4A_BOVIN
Sequence: MRLLGKLRASAASSAPLEPAFSNVLTPNRIPEFFIPPRLPTPYAPESSPPAAALPRRCAAEPDLWLRGADDGAGRTDWDPRSQAALSLPHLPRALTAYGFCALLESPHTRRKESLFLGSPSSAALPPAPRPRAHTYGGGGGDAPLAPGARSPIATPAARGGPSPSLDTLAPPPRCRRLLRAPEGLLRRALRAGRSRGLARARSVSSGDGEDDDEDESRASPGSPTQAPVTSLSPHRDPRPERLEAEGTVTLGRAGGALRLAAEYNRASGRLRVRLLRAEGPAGGAAEPRAPVGCRISFVLKPRGAVVRRSRRAVLEQDLCLDGLSEDEVRRLAVRVKAENRGRGLERGRLLGQGELLLGPLLLL
What is the function of this protein?
May be involved in inflammatory process.  May regulate cell architecture and adhesion (By similarity).
What are the official names of this protein?
C2 calcium-dependent domain-containing protein 4A, Nuclear-localized factor 1, Protein FAM148A.
What is the protein family that this protein belongs to?
Belongs to the C2CD4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FRDA_DROME
Sequence: MFAGRLMVRSIVGRACLATMGRWSKPQAHASQVILPSTPAIAAVAIQCEEFTANRRLFSSQIETESTLDGATYERVCSDTLDALCDYFEELTENASELQGTDVAYSDGVLTVNLGGQHGTYVINRQTPNKQIWLSSPTSGPKRYDFVGTVAAGRWIYKHSGQSLHELLQQEIPGILKSQSVDFLRLPYCS
What is the function of this protein?
Promotes the biosynthesis of heme as well as the assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways (PubMed:18540637).  May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe(2+) to Fe(3+) (PubMed:18540637).  May be able to store large amounts of the metal in the form of a ferrihydrite mineral by oligomerization (PubMed:18540637).  Required for ecdysteroidogenesis in the prothoracic gland which is necessary for larval to pupal transition (PubMed:25628335).
What are the official names of this protein?
Frataxin homolog, mitochondrial, Dfh.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NUOH_HELPH
Sequence: MSAYIIETLIKILILVAVFSALGGFATYIERKVLAYFQRRLGPCYVGPFGLLQVAADGIKLFTKEDIIPQGANKFIFTLAPIIAMVSAFVSMAPIPFFPNFTLFGYEIKPLISDINIGFLFFLAVGAAGIYAPILAGLASNNKYSLIGSARATIQLLSFEVVSTLTILAPLMVVGSLSLVEINHYQSGGFLDWLVFKQPLAFVLFLIASYAELNRTPFDLLEHEAEIVAGYCTEYSGLKWGMFFLAEYAHLFAFSFVISIVFFGGFNAWGFIPGGIAILIKAGFFVFLSMWVRATYPHVRPDQLMNMCWKIMLPLALLNIVLTGIIILI
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FBX44_MOUSE
Sequence: MAVGNINELPENILLELFIHIPARQLLLRCRPVCSLWRDLIDLVTLWKRKCLQEGFITEDWDQPVADWKIFYFLRSLQRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSKDQRKEFPNDQVKKYFVTSYYTCLKSQVVDLKAEGYWEELMDTTRPDIEVKDWFAARPDCGSKYQLCVQLLSSAHAPLGTFQPDPVMIQQKSDAKWSEVSHTFSNYPPGVRYIWFQHGGVDTHYWAGWYGPRVTNSSITIGPPLP
What is the function of this protein?
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
What are the official names of this protein?
F-box only protein 44, F-box only protein 6a.
Protein: Y1285_SULAC
Sequence: MTRVIVEAVVKPSEDKDKVINAIRNFFDFDKIREEEHGMEKLLIAESNSLTSLLKLHRLLREQRILDAARKYLMKSIVGSRITFMLNKQVAAIGKLSFIDKEHESPLGPIKVTIDYKDPVIVVDWLTPKTAKGVPLWENAIPPEE
What are the official names of this protein?
UPF0201 protein Saci_1285.
What is the protein family that this protein belongs to?
Belongs to the UPF0201 family.
Protein: CALGL_HOPST
Sequence: MAATLTPEQITEYKGIFEMFDEEGNGLVKTDDLESLMSLIGINPTKRDLANMAKDVDKDKKGTFNCDGFLVLMGIYHEKSKNQDEELRAAFKVFDKEHKGYIEWDTLKYVLMNAGEPLNEHEAELMMKEADKDGDGTIDYEEFVAMMTGESFKLTQ
What is the function of this protein?
May be involved in the cellular control mechanism of the secretion of toxins from the gland into the venom.
What are the official names of this protein?
Calglandulin.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family. Calglandulin subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Not found in venom.
Protein: UNG_ACIBY
Sequence: MQLTEQQQDKLSKVQLEESWKRSLTPFLLSPYMDSLRDFLFQQKQAQKTIYPPSKQIFNALNITPLDHVKVVILGQDPYHGPNQANGLSFSVQRGVALPPSLRNIFHELHTDLGVPISRHGDLTKWAEQGVLLLNSVLTVEAGQPTSHQKQGWEEFTDAVIDVLNEQREHIVFILWGAYAQRKGQRINREKHLVLTAAHPSPLAANRGGFFGCKVFSKTNQYLKQHGIEPIDWQLDA
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WZYE_ECOBW
Sequence: MSLLQFSGLFVVWLLCTLFIATLTWFEFRRVRFNFNVFFSLLFLLTFFFGFPLTSVLVFRFDVGVAPPEILLQALLSAGCFYAVYYVTYKTRLRKRVADVPRRPLFTMNRVETNLTWVILMGIALVSVGIFFMHNGFLLFRLNSYSQIFSSEVSGVALKRFFYFFIPAMLVVYFLRQDSKAWLFFLVSTVAFGLLTYMIVGGTRANIIIAFAIFLFIGIIRGWISLWMLAAAGVLGIVGMFWLALKRYGMNVSGDEAFYTFLYLTRDTFSPWENLALLLQNYDNIDFQGLAPIVRDFYVFIPSWLWPGRPSMVLNSANYFTWEVLNNHSGLAISPTLIGSLVVMGGALFIPLGAIVVGLIIKWFDWLYELGNREPNRYKAAILHSFCFGAIFNMIVLAREGLDSFVSRVVFFIVVFGACLMIAKLLYWLFESAGLIHKRTKSSLRTQVEG
What is the function of this protein?
Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units.
What are the official names of this protein?
Probable ECA polymerase.
What is the protein family that this protein belongs to?
Belongs to the WzyE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ALMA7_EMIHU
Sequence: MAGKDRKTIEKNYPGAEVDEGGRFKPLPPADDDAKLLVCEYPSLGVIRLDYDYPPALGDIDHPGSFYYDVFYRVVPGLTFGMCQKGEMPDEIKQRFIDAIKWLDAQGVAGITSDCGFFMNFQDLARTVTDKPVFMSSLCQLPAVVCAYAAHEHIALFTANGESLKPMRDLIKKECGVDPEESRFIIVGCQDVPGFEAVANGDRVDVDSVMPHIVRLAKETVAKYADTAKPIRAILFECTELPPYSDAVRAATRLPVFDAITSCNSFLAALMDNPRFGVNNWHLSWDGSQTDYRYGDNLSADLKAKLVNAEHAENVAAAERKLAKDRQKPKPATGTGTAFDA
What is the function of this protein?
Mediates cleavage of dimethylsulfonioproprionate (DMSP) into dimethyl sulfide (DMS) and acrylate.  DMS is the principal form by which sulfur is transported from oceans to the atmosphere and is a key component of the ocean sulfur cycle.
What are the official names of this protein?
Dimethylsulfonioproprionate lyase 7, DMSP lyase 7, Dimethylpropiothetin dethiomethylase 7.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family. ALMA1 subfamily.
Protein: OLFL3_XENTR
Sequence: MAGIVACILLVFVTVITAQQQAVFLEYIQGRMGVLEERLSQWHDQSSRYSGELRDFKNQVLKMLENIEKERESLRNEMENTNVRVDRLEREVDYIETQNPAPPCVEIDEKLTELHDAKKKKKEKYEKITGCPAADIPGKEETDEILIPPVIRKPYCSDTISQVTAMKILKRFGSSAGLWTKDLAGNSDRIYVFDGAGNDTVYVYPRMKEFTLSSSTRKAAKIKLPFPWIGTGHIVYDGNLYYIRQDNEFQVIKFNLANKTIIDSAVLPIEQQVPVYGLSKFNYIDIVADEEGLWVIYATKENEKNICLAKLDPSSLSIEQMWDTPCPIENAESAFVVCGSLYVVYNTKLPSRSRIQCVFDVSGTISSENVPIVYFPKRYGSHSSMKYNPKEKQIYAWDDGYQMLYKLNMKHRDELY
What is the function of this protein?
Secreted scaffold protein that plays an essential role in dorsoventral patterning during early development.  Stabilizes axial formation by restricting chordin (CHRD) activity on the dorsal side.  Acts by facilitating the association between the tolloid protease BMP1 and its substrate chordin (CHRD), leading to enhance chordin (CHRD) degradation by BMP1 (By similarity).
What are the official names of this protein?
Olfactomedin-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the OLFML3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: IF1_HELPY
Sequence: MARDDVIEVDGKVIEALPNATFKVELDNKHVVLCRISGKMRMHYIRIALGDRVKLELTPYSLDKGRITFRYK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPE_STRM5
Sequence: MSAVLDLTCELIARPSVTPDDAGCQTLLAARLKQAGFQCDHLRLGEVDNLWATHGQGAPVLVLLGHTDVVPPGPREAWASDPFTPQIREGVLYGRGTADMKGSVAAFVVAAEQFVAAHPDHTGTLAVLLTSDEEGDAIDGVRHVARLFAERGQRIDWCITGEPSSTATLGDLLRVGRRGSLSAKLRVQGVQGHVAYPEKARNPIHQAAPALAELSARRWDDGYESFPPTSLQISNIHAGTGANNVIPGELEVDFNIRYNPHWDAPKLEAEITALLDQHGLQYTLKWHRSGEPFYTPEGTLRATARAVLAEHIGRAPEESTGGGTSDARFIAPLGAQCIEVGPVNASIHQVDENVRVDELEALPGLYQRLVERLLV
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: SYL_STRPS
Sequence: MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTSENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKDMQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQAEAVVDYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGTGAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDAIAKIVACLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLVLPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHIETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALDKAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHLAEELWQTVAETDKSISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREELQEIALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ODPA_YEAST
Sequence: MLAASFKRQPSQLVRGLGAVLRTPTRIGHVRTMATLKTTDKKAPEDIEGSDTVQIELPESSFESYMLEPPDLSYETSKATLLQMYKDMVIIRRMEMACDALYKAKKIRGFCHLSVGQEAIAVGIENAITKLDSIITSYRCHGFTFMRGASVKAVLAELMGRRAGVSYGKGGSMHLYAPGFYGGNGIVGAQVPLGAGLAFAHQYKNEDACSFTLYGDGASNQGQVFESFNMAKLWNLPVVFCCENNKYGMGTAASRSSAMTEYFKRGQYIPGLKVNGMDILAVYQASKFAKDWCLSGKGPLVLEYETYRYGGHSMSDPGTTYRTRDEIQHMRSKNDPIAGLKMHLIDLGIATEAEVKAYDKSARKYVDEQVELADAAPPPEAKLSILFEDVYVKGTETPTLRGRIPEDTWDFKKQGFASRD
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
What are the official names of this protein?
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial, Pyruvate dehydrogenase complex component E1 alpha, PDHE1-A.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: VATI_METTH
Sequence: MSDMFLPARMRKLKIITLDQYSDSVVRSLHEEGVTQIDDISERIQQDAEWRQILKPSRATPYTGRVSSLLMKTSGILDFLGSVAAEEKGLRDTIREFINPPIFEKREVEELDTESLIERAEETLGRVESETRVMEEKLNELDSERSAVESSLSVAEKLKDFDIDFSDLQDSEYITGIAGRITAENLPELRDKLADITDELVISDREGENKAERILIIVTLKKHADSIASVLRRMEFERFEISELQGRPSEIISSSKTRLEEISRERKEIISKLRDINAEWEDELLVLREQLEIEKERNEVFSLFGETRKTVMLEAWVPLKEADRVIAVVEESSEGTALTDLEDPDPEEVPVLLDNPRFAKPYETFVEMYSPLKYNEIDPTIFMAFVFPFFFGFCLTDAGYGIIDALIGFILYRGLGKVNNFMRNFGIIMMSCGVWAFILGMVTNGFIGDFFPRFFNITLPTVIPAIDAFVNPQNILIMALTVGVLHINFGLILGARNNIRLGNMREALGSQIVWLILELGIILYLVGGMIFGAPLIILAFAMLLYYNGLFGLMDVSGFLGTLLSYARLLALCLSTGGIAMTVNILTGLSYEMIPVIGVVLAPIIFVFGHIANNAFQSLGAFINSLRLHYVEFFAQFYMGGKNKFNAFRAERNFTKIRR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit I, V-ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase 116 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KPRS_CHLTE
Sequence: METPIKIVAGRSNPELAKKIAAYLGTPLCDAKAENFSDGEISVNYFESIRGSDMFIIQSTNPPADNLMELLIMIDAAKRSSAYRITAVLPYYGYARQDRKDKPRVAITAKLVANLLTQAGADRILTMDLHAPQIQGFFDIPFDHLYSSVVLIDHVKNMDIADNLVVASPDVGGVKLARKFASELGTELVIVDKRRPKANVAEVMNIIGDVKGKNVLLVDDMIDTAGTIVNAAKAIKEAGGLKIYAAATHPILSGPAIERINTSVFEKVIVTDSLVSEHDFCSKIETVTISNLFGEAIKRIYDGESVSYLFDSKNISQKITNHH
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase, RPPK, 5-phospho-D-ribosyl alpha-1-diphosphate synthase, Phosphoribosyl diphosphate synthase, Phosphoribosyl pyrophosphate synthase, P-Rib-PP synthase, PRPP synthase, PRPPase.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T39AA_XENLA
Sequence: MPGGRRGPSRQQLSRSALPSLQTLVGGTCGNGTGLRNRNGSAIGLSAPPITALITPEPVRHCRIPELPVDGGLLFEFLFFIYLLVALFIQYINIYKSVWWYPYNHPASCTSLNFHLIDYHLAAFITVMLARRLVWALISEASQVGTSSVVHYTTLIIGRLVLLTLCGWIFCWTLVNLFRNHSLLNLLFLGYPFGVYVPLCCFHQDNRSQPLPTDCGYLVPDSLVDEGANGAGSLVRPKDFLSLLRESLREQLNSAPSVPSHSCPLSPDLIRNEVECLKSDFNRRIKEVLFNSLFSAYYVAFLPLCFVKSTQYYDMRWSCEHLIMVWINAFVMLSTQLLPPKYCDLLHRSASHLGKWQKLEHGAYSNAPQHIWSENTVWPQGVLVRHSRSLYKAVGPYNVAVPSEVSHARFYFLFHRPLRLLNLLLVIEGSLVLYQLYSLLRAEKWNHTLSIALILFCNYYVLFKLLRDRIVLGRAYSYPFSSYGLKPH
What are the official names of this protein?
Transmembrane protein 39A-A.
What is the protein family that this protein belongs to?
Belongs to the TMEM39 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: VSX1_BOVIN
Sequence: MTGRDALSDGRARSRALVPGGPSTGSRPRGFAITDLLGLEAELPAPEGPGPGSGCEGPAAAPRAGPGLGGSCPARGALPLGLGLLCGFGAQPPAAARAPCLLLADVPFLPPEGPEPLAPRFPGRPPPSAARQKRSESVSTSDEDSPSEDRSDRKASPAPSKRKKRRHRTVFTAHQLEELEKAFSEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRAKWRKREKRWGGSSVMAEYGLYGAMVRHCIPLPDSVLGSGEGGLLGSCAPWLLGMHKKSAGTIRKAESEEKLAGLWGSDHLKEGSSPHQAGPQRGLEEGSPVSGVEDVVIDLSSSTRQETDRAQQGVGAQGRPDSEGLEGLQPGKEGAL
What is the function of this protein?
Binds to the 37-bp core of the locus control region (LCR) of the red/green visual pigment gene cluster (By similarity).  May regulate the activity of the LCR and the cone opsin genes at earlier stages of development (By similarity).  Dispensable in early retinal development (By similarity).
What are the official names of this protein?
Visual system homeobox 1, Homeodomain protein RINX, Retinal inner nuclear layer homeobox protein, Transcription factor VSX1.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYE_STAAN
Sequence: MSDRIRVRYAPSPTGYLHIGNARTALFNYLYAKHYNGDFVIRIEDTDKKRNLEDGETSQFDNLKWLGLDWDESVDKDNGYGPYRQSERQHIYQPLIDQLLAEDKAYKCYMTEEELEAEREAQIARGEMPRYGGQHAHLTEEQRQQFEAEGRQPSIRFRVPQNQTYSFDDMVKGNISFDSNGIGDWVIVKKDGIPTYNFAVAIDDHYMQISDVIRGDDHISNTPKQIMIYEAFGWEPPRFGHMSLIVNEERKKLSKRDGQILQFIEQYRDLGYLPEALFNFIALLGWSPEGEEEIFSKEEFIKIFDEKRLSKSPAFFDKQKLAWVNNQYMKQKDTETVFQLALPHLIKANLIPEVPSEEDLSWGRKLIALYQKEMSYAGEIVPLSEMFFKEMPALGEEEQQVINGEQVPELMTHLFSKLEALEPFEAAEIKKTIKEVQKETGIKGKQLFMPIRVAVTGQMHGPELPNTIEVLGKEKVLNRLKQYK
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.