PharMolix/UniProtQA huggingface dataset:
Protein: PDCL3_HUMAN
Sequence: MQDPNADTEWNDILRKKGILPPKESLKELEEEAEEEQRILQQSVVKTYEDMTLEELEDHEDEFNEEDERAIEMYRRRRLAEWKATKLKNKFGEVLEISGKDYVQEVTKAGEGLWVILHLYKQGIPLCALINQHLSGLARKFPDVKFIKAISTTCIPNYPDRNLPTIFVYLEGDIKAQFIGPLVFGGMNLTRDELEWKLSESGAIMTDLEENPKKPIEDVLLSSVRRSVLMKRDSDSEGD
What is the function of this protein?
Acts as a chaperone for the angiogenic VEGF receptor KDR/VEGFR2, increasing its abundance by inhibiting its ubiquitination and degradation (PubMed:23792958, PubMed:26059764).  Inhibits the folding activity of the chaperonin-containing T-complex (CCT) which leads to inhibition of cytoskeletal actin folding (PubMed:17429077).  Acts as a chaperone during heat shock alongside HSP90 and HSP40/70 chaperone complexes (By similarity).  Modulates the activation of caspases during apoptosis (PubMed:15371430).
What are the official names of this protein?
Phosducin-like protein 3, HTPHLP, PhPL3, Viral IAP-associated factor 1, VIAF-1.
What is the protein family that this protein belongs to?
Belongs to the phosducin family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Endoplasmic reticulum.
Protein: CAS4_METJA
Sequence: MENYLEEELIIGGIEINYLYVCKTKLWYFVRGITMEQESDFVDLGKFLHEKSYFGEEKEVQIGSIKIDFIKKRDVIEIHEVKRGKQMEKAHIMQVLYYIYYLNSLGIKSKAILHYPKLKEIKEIELKENNKEEIKRAIKEIEYIKSLKEPPEPIYQKICKNCAYYELCFI
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  This protein may be a 5' to 3' ssDNA exonuclease.
What are the official names of this protein?
CRISPR-associated exonuclease Cas4.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated exonuclease Cas4 family.
Protein: NUOB_PHOV8
Sequence: MEVKKPTIKSIPYEDFKDNEYLENMVKQLNEGGTKVLVGCLDDLINWGRSNSLWPLTFATSCCGIEFMAVGAARYDFARFGFEVARASPRQADMIMVAGTITHKMAPVLKRLYDQMADPKYVIAVGGCAISGGPFKKSYHVLNGVDKILPVDVYIPGCPPRPEALLYGMIQLQRKVKLEKFFGGVNRKENEPQNPEQA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: T179A_MOUSE
Sequence: MALNNFLFAQCVCYFLAFLFSFVVVVPLSENGHDFRGRCLLFTEGMWLSANLTMQGRERFTVQEWGPPAACRFSLLASLLSLLLAAAHAWRTLFFLCKGHEGSFFYAFLNLLVSAFVVFLVFIASTIVSVGFTMWCDTITEKGSTPHSCEEFQETDLELNVDNSAFYHQFAIAQFGLWASWLAWLAITTLAFLKVYHNYRQEDLLDSLVHEKELLLARPTSRTSFQGEKSAVI
What are the official names of this protein?
Transmembrane protein 179.
What is the protein family that this protein belongs to?
Belongs to the TMEM179 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: YEGS_ECODH
Sequence: MAEFPASLLILNGKSTDNLPLREAIMLLREEGMTIHVRVTWEKGDAARYVEEARKFGVATVIAGGGDGTINEVSTALIQCEGDDIPALGILPLGTANDFATSVGIPEALDKALKLAIAGDAIAIDMAQVNKQTCFINMATGGFGTRITTETPEKLKAALGSVSYIIHGLMRMDTLQPDRCEIRGENFHWQGDALVIGIGNGRQAGGGQQLCPNALINDGLLQLRIFTGDEILPALVSTLKSDEDNPNIIEGASSWFDIQAPHDITFNLDGEPLSGQNFHIEILPAALRCRLPPDCPLLR
What is the function of this protein?
Probably phosphorylates lipids; the in vivo substrate is unknown.
What are the official names of this protein?
Probable lipid kinase YegS.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2625_HAEIG
Sequence: MTIENDYAKLKELMEFPAKMTFKVAGINREGLAQDLIQVVQKYIKGDYIPKEKRSSKGTYNSVSIDIIAENFDQVETLYKELAKVEGVKMVI
What are the official names of this protein?
UPF0250 protein CGSHiGG_02625.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.
Protein: Y2628_BORBU
Sequence: MSYYVLSKIFLYSGYLVIGFLSFTIFNKNLRNKIRDKLKNLYFLYYLTFFTLFIISSNLSYYFTEKQLLEDFNIFEKEFFEIHKINEQFFQKYLLNFPVPIRMELMSKFDPLYTVFNASFEKYAKNIGKSSYEIQTNYKNYIRTTNSEIKEKLEQIKENITPIYNKYKLPILNGENTEISIDENGNIIPVIKNTNGQITELLFYDQNYNLIPFKKFESYKVRFDLIPENKNINFKELINVYYLDEKNIITPIEYYKNNIDMSPYYIDLQENKDDFLKAIKIKKEYGLYIEKKKQLQNLTENDKLDDFKEFLLKNNNIFSLNTIFSNGNPIFTYAINVKAKSIINYLITKEFNINLTNQNSQTALHSAIIQKYDLNFIKSLIEKGANPNIRDGDNKLPIDYSDKTSEIYKYLIGI
What are the official names of this protein?
Putative ankyrin repeat protein BB_B28.
Protein: SMAD5_CHICK
Sequence: MTSMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHSEFNPQHSLLVQFRNLSHNEPHMPHNATFPDSFQQPNSTPFSISPNSPYPPSPASSTYPSSPASSGPSSPFQLPADTPPPAYMPPDDQMGQDNSQSMDTSNTMIPQIMPNISTRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS
What is the function of this protein?
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase.  SMAD5 is a receptor-regulated SMAD (R-SMAD) (By similarity).
What are the official names of this protein?
Mothers against decapentaplegic homolog 5, MAD homolog 5, Mothers against DPP homolog 5, SMAD family member 5, SMAD 5, Smad5.
What is the protein family that this protein belongs to?
Belongs to the dwarfin/SMAD family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4 (By similarity).
Protein: MASZ_MYCBT
Sequence: MTDRVSVGNLRIARVLYDFVNNEALPGTDIDPDSFWAGVDKVVADLTPQNQALLNARDELQAQIDKWHRRRVIEPIDMDAYRQFLTEIGYLLPEPDDFTITTSGVDAEITTTAGPQLVVPVLNARFALNAANARWGSLYDALYGTDVIPETDGAEKGPTYNKVRGDKVIAYARKFLDDSVPLSSGSFGDATGFTVQDGQLVVALPDKSTGLANPGQFAGYTGAAESPTSVLLINHGLHIEILIDPESQVGTTDRAGVKDVILESAITTIMDFEDSVAAVDAADKVLGYRNWLGLNKGDLAAAVDKDGTAFLRVLNRDRNYTAPGGGQFTLPGRSLMFVRNVGHLMTNDAIVDTDGSEVFEGIMDALFTGLIAIHGLKASDVNGPLINSRTGSIYIVKPKMHGPAEVAFTCELFSRVEDVLGLPQNTMKIGIMDEERRTTVNLKACIKAAADRVVFINTGFLDRTGDEIHTSMEAGPMVRKGTMKSQPWILAYEDHNVDAGLAAGFSGRAQVGKGMWTMTELMADMVETKIAQPRAGASTAWVPSPTAATLHALHYHQVDVAAVQQGLAGKRRATIEQLLTIPLAKELAWAPDEIREEVDNNCQSILGYVVRWVDQGVGCSKVPDIHDVALMEDRATLRISSQLLANWLRHGVITSADVRASLERMAPLVDRQNAGDVAYRPMAPNFDDSIAFLAAQELILSGAQQPNGYTEPILHRRRREFKARAAEKPAPSDRAGDDAAR
What is the function of this protein?
Involved in the glycolate utilization.  Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
What are the official names of this protein?
Malate synthase G.
What is the protein family that this protein belongs to?
Belongs to the malate synthase family. GlcB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_WOLSU
Sequence: MLNIYDYTLEELKRRLHPPFRAKQLYHWLYHRYEEEFEKMHNLSKEIRQKLTQDYSATLTKVVREEVSEDGSRKYLFQTHDGLTYEAVLLKMKEKKEDEEGRIVEGEKYTICVSSQVGCKVGCSFCFTAKGGFVRNLSAGEIVYQIVALKRLNALAPEKRVNIVYMGMGEPLDNFENLIQAIRILSELDGLSISTKRQTISTSGIAPKIEKLGALDLGVQLAISLHAVDDELRTRLIPMNKAYNIASIIEAVRRFPIDSRKRVMFEYLVIKGVNDDEKSAKTLLKLLNGIKSKVNLIYFNPHEGSEFERPLESKMVAFQKYLTDRGLLCTIRESKGIDISAACGQLREKIIKEENCGNR
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UROK_HUMAN
Sequence: MRALLARLLLCVLVVSDSKGSNELHQVPSNCDCLNGGTCVSNKYFSNIHWCNCPKKFGGQHCEIDKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHNYCRNPDNRRRPWCYVQVGLKLLVQECMVHDCADGKKPSSPPEELKFQCGQKTLRPRFKIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRSHTKEENGLAL
What is the function of this protein?
Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin.
What are the official names of this protein?
Urokinase-type plasminogen activator, U-plasminogen activator, uPA.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYK_RAT
Sequence: MLMQAAVRLVRGSLRQTSWAEWGQRELRLGQLAPFTTLRKDKPLSDRRSELKRRLKAEKKLAEKEAKQKELSEKQLNQTTAAAATNHTADNGVGAEEETLDPNQYYKIRSQAVQQLKVSGEDPYPHKFHVDISLTQFIQEYSHLQPGDHLTDITLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFVHINNKLRRGDIIGVEGNPGKTKKGELSIVPREMTLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNDFVRQKFIIRSKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYHDLMEITEKMLSGMVRSITGSYKITYHPDGPEGQAYEIDFTPPFRRISMVEELEKVLGVKLPETSLFETEETRKILDDICVARAVECPPPRTTARLLDKLVGEFLEVTCISPTFICDHPQIMSPLAKWHRCKEGLTERFELFVMKKEICNAYTELNDPVRQRQLFEEQAKAKAAGDDEAMFIDENFCTALEYGLPPTAGWGMGIDRVTMFLTDSNNIKEVLLFPAMKPEDKKETATATETPESTEASPSV
What is the function of this protein?
Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA (PubMed:6315704).  When secreted, acts as a signaling molecule that induces immune response through the activation of monocyte/macrophages (By similarity).  Catalyzes the synthesis of the signaling molecule diadenosine tetraphosphate (Ap4A), and thereby mediates disruption of the complex between HINT1 and MITF and the concomitant activation of MITF transcriptional activity (PubMed:3988754, PubMed:2995387, PubMed:19524539).
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein. Secreted. Note=Secretion is induced by TNF-alpha (By similarity). Cytosolic in quiescent mast cells. Translocates into the nucleus in response to mast cell activation by immunoglobulin E (PubMed:19524539, PubMed:23159739).
Protein: ASSY_BURP0
Sequence: MTTILENLPAGQKVGIAFSGGLDTSAALHWMRIKGAVPYAYTANLGQPDEDDYDAIPKRAIQYGAEGARLIDCRAQLVAEGIAALQCGAFHISTAGVTYFNTTPIGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLVNPDLKIYKPWLDQQFIDELGGRAEMSEFMRQAGFEYKMSAEKAYSTDSNLLGATHEAKDLESLESGIKIVNPIMGVAFWRDDVKIDKEEVTIRFEEGRPVALNGVEYKDAVALLLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGLALLYIAYERLVTGIHNEDTIEQYRENGRRLGRLLYQGRWFDPQAIMLRETAQRWVARAVTGEVTVELRRGNDYSIIGTRSPNLTYQPERLSMEKVQSMFSPRDRIGQLTMRNLDITDTRDKLRIYSQVGLLAAGESSALPKLKEDESGN
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK31_TRICV
Sequence: MPKPEIHPTWFNETPIVCDGKPLCYIGSTKSELQVDIWLANHPFYTDSQTIIDSEGRVERFMKKYGINSTND
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LFTR_SALRD
Sequence: MPDDLTPDLLIRAYANGVFPMGDDDTGIVRWHAPDPRAYLPLDAFHIPHNLRRRVRRREFSVTADRAFASVIEACADRARTWITPRIIRVYTELHERGYAHSVECWQEGDLAGGLYGVGLKGAFFGESMFYRVSNASKVALVHLVRQLRAGGFTLLDTQYSTEHLERFGVTTVPRPAFEQKLIRALDVSPDWWPLADAEAADLDTPVSEFSAAAPTLRGNESPPNG
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURT_BURL3
Sequence: MQIGQRLGTPLSPSATRVMLLGAGELGKEVIIALQRLGVEVVAVDRYPDAPGHQVAHRAHVIDMTDAAALRAIVEAERPHLIVPEIEAIATDALAAIEAAGLAEVIPTARATQLTMNREGIRRLAAEELGLPTSPYAFADSFEAFSAAIAKIGMPCVVKPVMSSSGKGQSVVKTEADVKPAWDYAMAGGRVNHGRVIVEGFIDFDYEITQLTVRAIDPATDATRTYFCEPVGHVQVAGDYVESWQPQPMSAVALEKSREIAHKVTEALGGRGMFGVELFVNGDDVWFSEVSPRPHDTGLVTLASQRQSEFELHARAILGLPVDPALGTPAASAVIYGGLDERGIAFEGVREALAVPGADLRLFGKPESFAKRRMGVALATGATVDEARERAKRAAAAVRPVSAR
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: DEF2_GALME
Sequence: DKLIGSCVWGATNYTSDCNAECKRRGYKGGHCGSFWNVNCWCEE
What is the function of this protein?
Has antibacterial activity against the Gram-positive bacterium S. lutea (MIC=1. 9 uM).  Lacks antibacterial activity against the Gram-positive bacteria L. monocytogenes and M. luteus, and the Gram-negative bacteria E. coli D31, E. coli ATCC 25922, and S. typhimurium.  Has antifungal activity against A. niger (MIC=2. 9 uM), C. albicans (MIC=2. 9 uM), C. fructus (MIC=2. 9 uM), C. wickerhamii (MIC=2. 9 uM), P. pastoris (MIC=2. 9 uM), P. stiptis (MIC=2. 9 uM), P. tannophilus (MIC=2. 9 uM), T. harzianum (MIC=2. 9 uM), and Z. marxianus (MIC=2. 9 uM), but lacks antifungal activity against C. albidus, F. oxysporum, and S. cerevisiae.
What are the official names of this protein?
Defensin-like peptide.
What is the protein family that this protein belongs to?
Belongs to the invertebrate defensin family. Type 2 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HDAC9_XENLA
Sequence: MLQTIYESESYFSSDGVAGREQLLAEQRMHAMIGKDIKSEFPIGLESISPLDLRTDLRTAVPVGDPGLREKQLQQELLIIKQQQQIQKQLLIAEFQKQHENLTRQHQVQLQEHLKLQQELLAMKQQQELLEREKEQKMEQQRKEQEAERHRQEQQLCHPRSKDRVKERAVASTEVKQKLQEFILSKSATKEPLTNGTSHSMGRHPKLWYTAAHHTSLDQSSPPPSGTSPTYKCPPPGNQDDFPLRKTASEPNLKVRSRLKQKVVERRSSPLLRRKDSIVSSSYKKRIFEVAESSVSSSSPVSGPSSPNNGPVAMEAEHETPVLSVNSRIENLVSHHHLVHHERSLSLLNLYTSPSLPNITLGLHATATQLNTSSSLKEQQKYDPQAPRQGVSMAGQYAGGIPTSSNHVSLEGKANSHQAILQHLLLKEQMRQQKILASGGTPVLHQSPLAAKDRVSPAGRVAHKLPRHRPLHRTQSAPLPQSTLAQLVIQQQHQQFLEKQKQYQQQIHMNKILSKSIEQLRQPEGHLEEAEEDLHGDNLMQEKSSSIDNTRSYSSTDLRTGPFGSVKVKEEPPDSENEIKTHLQSEQKSVFAQQVT
What is the function of this protein?
Devoided of intrinsic deacetylase activity, promotes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) by recruiting other histone deacetylases.  Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.  Represses MEF2-dependent transcription.
What are the official names of this protein?
Histone deacetylase 9, Histone deacetylase-related protein, MEF2-interacting transcription repressor MITR.
What is the protein family that this protein belongs to?
Belongs to the histone deacetylase family. HD type 2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: GD_BHV1C
Sequence: MQGPTLAVLGALLAVAVSLPTPAPRVTVYVDPPAYPMPRYNYTERWHTTGPIPSPFADGREQPVEVRYATSAAACDMLALIADPQVGRTLWEAVRRHARAYNATVIWYKIESGCARPLYYMEYTECEPRKHFGYCRYRTPPFWDSFLAGFAYPTDDELGLIMAAPARLVEGQYRRALYIDGTVAYTDFMVSLPAGDCWFSKLGAARGYTFGACFPARDYEQKKVLRLTYLTQYYPQEAHKAIVDYWFMRHGGVVPPYFEESKGYEPPPAADGGSPAPPGDDEAREDEGETEDGAAGREGNGGPPGPEGDGESQTPEANGGAEGEPKPGPSPDADRPEGWPSLEAITHPPPAPATPAAPDAVPVSVGIGIAAAAIACVAAAAAGAYFVYTRRRGAGPLPRKPKKLPAFGNVNYSALPG
What is the function of this protein?
Envelope glycoprotein that binds to host cell entry receptors.  May trigger fusion with host membrane, by recruiting the fusion machinery composed of gB and gH/gL (By similarity).
What are the official names of this protein?
Envelope glycoprotein D, gD, Glycoprotein IV.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein D family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs.
Protein: 5HT5A_HUMAN
Sequence: MDLPVNLTSFSLSTPSPLETNHSLGKDDLRPSSPLLSVFGVLILTLLGFLVAATFAWNLLVLATILRVRTFHRVPHNLVASMAVSDVLVAALVMPLSLVHELSGRRWQLGRRLCQLWIACDVLCCTASIWNVTAIALDRYWSITRHMEYTLRTRKCVSNVMIALTWALSAVISLAPLLFGWGETYSEGSEECQVSREPSYAVFSTVGAFYLPLCVVLFVYWKIYKAAKFRVGSRKTNSVSPISEAVEVKDSAKQPQMVFTVRHATVTFQPEGDTWREQKEQRAALMVGILIGVFVLCWIPFFLTELISPLCSCDIPAIWKSIFLWLGYSNSFFNPLIYTAFNKNYNSAFKNFFSRQH
What is the function of this protein?
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen.  The activity of this receptor is mediated by G proteins.
What are the official names of this protein?
5-hydroxytryptamine receptor 5A, 5-HT-5, 5-HT-5A, 5-HT5A, Serotonin receptor 5A.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NU5M_CHOCR
Sequence: MYLLILFLPLLGSLISGFGGRWLGCRGTNTFSTLCVVVSSLFSLLAFFEIGLTNTTCTIFLVSWIKSGAFYVSWGFLFDSLTVTMLVVITLVSSLVHIYSIKYMENDPHQPRFMSYLEIFTFFMLILVTADNLIQMFLGWEGVGLASYLLINFWYTRLAANQSAIKALIVNRVGDFGLSLGIFLIFWVFNSVDYSVIFSLVPLFDNQFLTFLGFKLHVLTLISLFLFIGAIGKSAQLGLHTWLPDAMEGPTPVSALIHAATMVTAGVFLMIRFSPLLEFSPTILFILITFGSLTAFFAAVTGVFQHDLKRVIAYSTCSQLGYMIFSCGMSCYDVSLFHLANHAFFKALLFLSAGSVIHAVSNEQDMRRMGSLLKFMPLTYSVMLIGTLALIGFPFLTGFYSKDFILELTQISSYSNLQMSYISFACWLGTMSVFFTSFYSFRLIYLTFLNNTNLAKSSLNLVHESSLLMIFPLIILSIGSIFAGYLIRDLFVGSGSDFWGAAIFILPKHSTFIEAEELPIVVKWLPFILSLLGIFFASFVQIFLKTFYFKSNLQNLLSFFTFLINKKWYWDVLYNRLIVLPILNFGYSISFKILDRGFIELSGPYGFTKFVSFWSQILIKLQTGQITHYLFFMIFTFCSFSIILVYSYINLTFNLLLLFFTLFFFI
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 5, NADH dehydrogenase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CB29_MAIZE
Sequence: MASSTMALSSTAFAGKAVNVPSSLFGEARVTMRKTAAKAKPAASSGSPWYGPDRVLYLGPLSGEPPSYLTGEFPGDYGWDTAGLSADPETFAKNRELEVIHSRWAMLGALGCVFPELLARNGVKFGEAVWFKAGSQIFSEGGLDYLGNPSLIHAQSILAIWACQVVLMGAIEGYRVAGGPLGEVVDPLYPGGTFDPLGLADDPEAFADVKVKELKNGRLAMFSMFGFFVQAIVTGKGPLENLADHLADPVNNNAWAYATNFVPGK
What is the function of this protein?
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.
What are the official names of this protein?
Chlorophyll a-b binding protein M9, chloroplastic, LHCII type I CAB-M9, LHCP.
What is the protein family that this protein belongs to?
Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein.
Protein: DTD_DICNV
Sequence: MIGLIQRVERASVCVEGKEIGAIDRGLLVFVGIERADSAQQAEKLAQKLLNYRVFEDELGKMNLNVQQIGGELLLVSQFTLAANTQKGNRPSFDPAMAPQEAEPLFDYFCQTVHTHYPHTATGRFGADMRVHLINDGPVTFWLHV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UB2Q2_MOUSE
Sequence: MSVSGLKAELKFLASIFDKNHERFRIVSWKLDELHCQFLVPPPPPPPGSSLSPPPPLTLHCNITESYPSSSPIWFVDSDDPNLTSVLERLEDTKNNSSLRQQLKWLICDLCRLYNLPKHLDVEMLDQPLPTGQNGTTEEVTSEEEEEEEMAEDIEDLDHYEMKEEEPINGKKSEDEGIEKENLAILEKIRKTQRQDHLNGAVSGSVQASDRLMKELRDVYRSQSYKAGIYSVELINDSLYDWHVKLHKVDSDSPLHSDLQILKEKEGIEYILLNFSFKDNFPFDPPFVRVVLPVLSGGYVLGGGALCMELLTKQGWSSAYSIESVIMQINATLVKGKARVQFGANKNQYNLARAQQSYNSIVQIHEKNGWYTPPKEDG
What is the function of this protein?
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.  In vitro catalyzes 'Lys-48'-linked polyubiquitination.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 Q2, E2 ubiquitin-conjugating enzyme Q2, Ubiquitin carrier protein Q2, Ubiquitin-protein ligase Q2.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_MYCGI
Sequence: MARVKRALNAQKKRRTVLKASKGYRGQRSRLYRKAKEQQLHSLTYAYRDRKARKGDFRKLWITRINAAARLNGITYNRLIQGLKAAGVEVDRKNLAEIAVSDAAAFAALAEVAKAALPADVNAPSGEAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.