PharMolix/UniProtQA huggingface dataset:
Protein: PUR2_STRSU
Sequence: MKLLVVGSGGREHAIAKKLLESEQVEQVFVAPGNDGMTLDGIELINIGISEHSALINFAKENDIAWTFVGPDDALAAGIVDDFEQAGLKAFGPSRLAAELEWSKDFAKQIMVKYGIPTAAFGTFSNFEEAKAYIEEQGAPIVVKADGLALGKGVVVAETVEQAVEAAREMLLDNKFGDSGARVVIEEFLAGEEFSLFALVNGDQFYILPTAQDHKRAFDGDQGPNTGGMGAYVHVPHLPQSVVDTAVDTIVKPILEGMITEGRSYLGVLYAGLILTDQGPKVIEFNARFGDPETQIILPRLTSDFAQNIDDILHKRPTQLTWLNSGVTLGVVVASNGYPLDYEKGVTLPAKTEGDITTYYAGARFAENSRALLSNGGRVYMLVTTADTVQDAQEKIYSELKNQDTTGLFYRTDIGSKAVK
What are the official names of this protein?
Phosphoribosylamine--glycine ligase, GARS, Glycinamide ribonucleotide synthetase, Phosphoribosylglycinamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the GARS family.
Protein: RS15_BURO1
Sequence: MSVADIKKSEVVAQFARGTNDTGSPEVQVALLTARIVELTGHFKTHAKDHHSRRGLLRMVSRRRKLLDYLKGKDADRYRALIEKLGLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: PG170_MONPV
Sequence: MYLLFIILMYLLPFSFQTSEPAYDKSVCDSGNKEYMGIEVYVEATLDEPLRQTTCESEIHKYGASVSNGGLNISVDLLNCFLNFHTVGVYTNRDTVYAKFASLDPWTTEPMNSMTHDDLVKLTEECIVDIYLKCEVDKTKDFMKTNDNRLKPRDFKTVPPSNVGSMIELQSDYCVNDVTAYVKIYDECGNIKQHSIPTLRDYFTTKNGQPRKILKKKIDNC
What is the function of this protein?
May interact with several cellular chemokines to interfere with chemokine-glycosaminoglycan (GAG) interactions at the cell surface to alter chemotaxis of nearby responsive cells.
What are the official names of this protein?
Protein OPG170.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG170 family.
Protein: IF2_LACE2
Sequence: MANMRVHELAKELNITSKDITDMLSNSEKTYKPVSGLTDAEISSVRKKFAPAPKVENKPAAQPAKQSQPVKNDNRDNRQQNQAPKQPQQGTQNKSGNADDKKHISQVYFPQNSSRDKNSRRDNNNRDGQRDNNGGYRNNDRNNGGYRNNDRGNNGYRNNDRNNNGGYGNRDNNGGYRNNDRNNNGGYGNRDNNGGYRNNDRNNGGYRNNDRNNNGGYGNRDNNGGYRNNDRNNNGGYGNRDNNGGYRNNDRNNNGGFRNDRNGQSGNGGFRKDNDQNRGGFNGGQRRNNDRRDSAPKEEFDFSAKPDSRRHDSRIDSKKNDRKRDNEAKENLKFANSRFDKKPMTKPEKKEKEEETIKQLVLPDTLTIKELADKMKVAPAALVKKLFLQGKVVTINEEIDYDAAEEIALEFNCICEHEEKVDVIAELLKEDEEPEDKLVPRPPVVCVMGHVDHGKTSLLDAIRETHVTAKESGGITQKIGAYQVNVNGNLITFLDTPGHEAFTAMRMRGAQATDIAILVVAADDGVMPQTIEAINHAKAAGVEIIVAVNKIDKPNANIEKVKQELTEYGLIAEDWGGSTTFVPVSAHTKQGIDELLDMILLTAEVNELKANPDRKARGIVIEAELDKGRGPVASILVQKGTLHVGDAVSAGSCYGKIRAMIDDKGNRVKVAGPSTPVEILGLNDVPNAGEIIMAADSEKEARSIAETFISEGRKKLLDDTKHKVSLDALFEQIQAGNMKELNIIIKADVQGSVEAVKSSLVRLSNEEVVVKVIHGGVGNVNESDVVLASASNAIIIAFNVKPDNQARIVAEREKVDLRLYSVIYNAIEDVEAALKGMLEPIYEEKIIGHARIMQIFKASGVGNIAGCIVEEGRITRDSVVRITRGSEKVYEGPIASLKHFKDEVKEIKAGTECGMVFEKFNDIQPEDMIEAHIMVEVPR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VAPA_BOVIN
Sequence: MASASGTMAKHEQILVLDPPTDLKFKGPFTDVVTTNLKLRNPSDRKVCFKVKTTAPRRYCVRPNSGIIDPGLTVTVSVMLQPFDYDPNEKSKHKFMVQTIFAPPNISDMEAVWKEAKPDELMDSKLRCVFEMPNENDKLNDMEPSKAVPLNAAKQDGPVPKPHSVSLSDTETRKLVEECKRLQGEMMKLSEENRLLRDEGLRLRKVAHSEKPGSTSAVSFRENVTSPLPSLLVVIAAIFIGFFLGKFIL
What is the function of this protein?
Binds to OSBPL3, which mediates recruitment of VAPA to plasma membrane sites.  The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1 (ITGB1) activation at the cell surface.  With OSBPL3, may regulate ER morphology.  May play a role in vesicle trafficking.
What are the official names of this protein?
Vesicle-associated membrane protein-associated protein A, VAMP-A, VAMP-associated protein A, VAP-A.
What is the protein family that this protein belongs to?
Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Cell junction, tight junction. Cell membrane; Single-pass type IV membrane protein. Note=Present in the plasma membrane and in intracellular vesicles, together with SNARE proteins. May also associate with the cytoskeleton. Colocalizes with OCLN at the tight junction in polarized epithelial cells.
Protein: RF1_LISMO
Sequence: MYDRLQAVEDRYDELNELLSDPDVVSDPKRLRDLSKEQSGITATVETYREYKNVNEQINETKELLGEKLDDEMREMAKEEFAELQKEKTDLEERLKLLLVPKDPNDDKNVILEIRGAAGGDEAALFAGDLFRMYSKYAESRGWKVEIMDANPTGIGGYKEIIAMMNGNDAFSRMKYENGAHRVQRVPETESGGRIHTSTATVAILPEAEEVEIELHDKDIRTDTFASTGAGGQSVNTTMSAVRLTHIPTGIVVSMQDERSQLKNKDKAMKVLRARVYDKFEREAREEYDANRKSAVGTGDRSERIRTYNYPQNRVTDHRIGLTIQKLDQIMEGKLDEIIDALILEDQTSKLEHLNDAN
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN485_HUMAN
Sequence: MAPRAQIQGPLTFGDVAVAFTRIEWRHLDAAQRALYRDVMLENYGNLVSVGLLSSKPKLITQLEQGAEPWTEVREAPSGTHAVEDYWFETKMSALKQSTSEASVLGERTKSVMMEKGLDWEGRSSTEKNYKCKECGKVFKYNSSFISHQRNHTSEKPHKCKECGIAFMNSSSLLNHHKVHAGKQPYRCIECGKFLKKHSTFINHQRIHSREKPHKCIECGKTFRKNSILLSHQRIHTGQKPYKCNDCGKAFAQNAALTRHERIHSGEKPFKCNKCGRAFRDNSTVLEHQKIHTGEKPYQCNECGKAFRKSSTLISHQRMHTGEKPYHCSKCGKSFRYSSSFAGHQKTHSGNKPYQCRDCGKAFTKSSTLTGHQRIHTGEKPYHCKKCGKAFRHSSGLVEHQRLHTGEKPYKCNECGKAFPRSSALKQHKKIHNKERAMKCS
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 485.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL35_BRUAB
Sequence: MPKMKTKSAAKKRFKITGTGKVKAAAAGKRHGMIKRSNKFIRDARGTMVLADADAKIVKQFLPNGL
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: TRMD_LEPCP
Sequence: MRFDVLTLFPELFEPFLHAGVTRRAFESGQVDVKLWQLRDFAEDNYKRVDDRPYGGGPGMVMLVEPLERALRAVRAQAGDAAPLIHFTPAGAPMTQKRVRELAAGPGAVLLCGRYEGIDQRFISRHVDEEISLGDFVLSGGELPALALLDAVTRLQPGVLNDAASHQQDSFSDGLLDCPHYSRPERLGEAAADAVPAVLLSGHHARVASWRREQQLRITALRRPDLIDAARAAGALSPADERLLASLQL
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPB_THEM4
Sequence: MKFGVIGYKGKMGKLITKTFSNRGHNCVLFVDKDEIEQIDIPEVIVDFSLKDALDKTINLCKKNKSNLVIGTTGFSNEDLEKLQKLSKEVALIQSYNFSLGVNIIVEILNKLNNILKDWDCEIFEIHHSQKKDKPSGTALMFKDALKKEVNINSSRLGGIPGDHTIFFANQGELISISHRTISREVFALGALKAAEWILNKKNGFYTFKDILKEELE
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP61_VIBC1
Sequence: MAAPGEALTSSGYIAHHLSNLSLAKLGLVADEASFWNVHIDSLFFSWFTGLIFLGIFYKVAKRTTAGVPGKLQCAVEMIVEFVAENVKDTFHGRNPLIAPLALTIFCWVFLMNVMDLVPIDFLPYPAEHWLGIPYLKVVPSADVNITMAMALGVFALMIYYSIKVKGLGGFAKELALHPFNHPLMIPFNLLIEVVSLLAKPLSLGMRLFGNMFAGEVVFILCAAMLPWYLQWMGSLPWAIFHILVITIQAFVFMMLTIVYLSMAHEDSDH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a 1, ATP synthase F0 sector subunit a 1, F-ATPase subunit 6 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RECX_CLOBB
Sequence: MAKITKLEVQKRNKERVNVFLDEDYAFSISAELIYKEGIKVKDSVNSEKLKVLANKDAIIKCREAAIKTIERNLKTEKQVRDKLNLKGYDEDSITKAIDFLKEYNFLDDKDYANKFVKDKLKCQGSNKIRYSLMQKGVSKDVIEEELSSIDKENEKESALILAQKKLNSLRKTEDDTYKISNKLYRFLLSKGYGYDIIKDVVKEAINFELYD
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATY_ECO8A
Sequence: MYVVSTKQMLNNAQRGGYAVPAFNIHNLETMQVVVETAANLHAPVIIAGTPGTFTHAGTENLLALVSAMAKQYHHPLAIHLDHHTKFDDIAQKVRSGVRSVMIDASHLPFAQNISRVKEVVDFCHRFDVSVEAELGQLGGQEDDVQVNEADAFYTNPAQAREFAEATGIDSLAVAIGTAHGMYASAPALDFSRLENIRQWVNLPLVLHGASGLSTKDIQQTIKLGICKINVATELKNAFSQALKNYLTEHPEATDPRDYLQSAKSAMRDVVSKVIADCGCEGRA
What is the function of this protein?
Catalytic subunit of the tagatose-1,6-bisphosphate aldolase GatYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6-bisphosphate (TBP).  Requires GatZ subunit for full activity and stability.  Is involved in the catabolism of galactitol.
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit GatY, TBPA, TagBP aldolase, D-tagatose-bisphosphate aldolase class II, Tagatose-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class II fructose-bisphosphate aldolase family. TagBP aldolase GatY subfamily.
Protein: Y594_MYCLE
Sequence: MTAVEGSSLTALNKGRLFASFDVDAFEVPGGRDEIWRFTPLRRLRGLHDGSAVANGKVHIRVSQQSGVQTEIVGRGDGRLGQGGIPTDRVAAQAFSSFQSATVVTVGRDMQIATPINIAVTGPDKGAVVYGHLQIRVCKFGEAVVVIDHRGSGTYADNVEFIVEAAARLTVVWIADWADDMVHLSAHHALLGKDAVLRHITVTLGGEVVRVSANVRFSGPGGDAELLGLYFADDGQHLESRLLVDHAHPDCKSNVLYKGALQGDPVSSRPDAHTVWVGDVLIHPEATGTDTFEVNRNLVLTNGVRADSVPNLEIETDEIVGAGHASATGRFDDEQLFYLRSRGIGEEQARRLLVRGFFGEIISKIAVPQVRERLIAAIEHELTITESRSTAS
What are the official names of this protein?
UPF0051 protein ML0594.
What is the protein family that this protein belongs to?
Belongs to the UPF0051 (ycf24) family.
Protein: FUMC_MYCTU
Sequence: MAVDADSANYRIEHDTMGEVRVPAKALWRAQTQRAVENFPISGRGLERTQIRALGLLKGACAQVNSDLGLLAPEKADAIIAAAAEIADGQHDDQFPIDVFQTGSGTSSNMNTNEVIASIAAKGGVTLHPNDDVNMSQSSNDTFPTATHIAATEAAVAHLIPALQQLHDALAAKALDWHTVVKSGRTHLMDAVPVTLGQEFSGYARQIEAGIERVRACLPRLGELAIGGTAVGTGLNAPDDFGVRVVAVLVAQTGLSELRTAANSFEAQAARDGLVEASGALRTIAVSLTKIANDIRWMGSGPLTGLAEIQLPDLQPGSSIMPGKVNPVLPEAVTQVAAQVIGNDAAIAWGGANGAFELNVYIPMMARNILESFKLLTNVSRLFAQRCIAGLTANVEHLRRLAESSPSIVTPLNSAIGYEEAAAVAKQALKERKTIRQTVIDRGLIGDRLSIEDLDRRLDVLAMAKAEQLDSDRL
What is the function of this protein?
Involved in the TCA cycle.  Catalyzes the stereospecific interconversion of fumarate to L-malate.
What are the official names of this protein?
Fumarate hydratase class II, Fumarase C, Aerobic fumarase, Iron-independent fumarase.
What is the protein family that this protein belongs to?
Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRX_PSEPU
Sequence: MTISILGARVIDPKTGLDQVTDLHLDGGRIAAIGAAPAGFSASRTIQADGVVAAPGLVDLGVSLREPGYSRKGNIRSETRAAVAGGVTSLCCPPQTRPVLDTLAVAELILDRAREAANSKVYPIGALTKGLEGEQLAELVALRDTGCVAFGNGLKQIPNNRTLARALEYAATFDLTVVFHSQDRDLAEGGLAHEGAMASFLGLPGIPESAETVALARNLLLVEQSGVRAHFSQITSARGAQLIAQAQELGLPVTADVALYQLILTDESVRQFSSLYHVQPPLRTAKDRDGLRAAVKSGVIQAISSHHQPHERDAKLAPFGATEPGISSVELLLPLAMTLVQDGLLDLPTLLARLSSGPAAALRVPAGELKVGGAADLVLFDPQASTVAGEQWSSRGENCPFIGHCLPGAVRYTLVDGHVCHGPE
What is the function of this protein?
Non-functional DHOase.
What are the official names of this protein?
Dihydroorotase-like protein, Aspartate carbamoyltransferase 44 kDa non-catalytic chain.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. PyrC' subfamily.
Protein: RM04_YEAS7
Sequence: MWKRSFHSQGGPLRARTKFTKPKPKQPVLPKDKIRPPTQLTHHSNNLRITEPIPPTTSNLRCPDDHPLWQFFSNKKFIRSADDLPPSSHIRPWSIPELRHKSFNDLHSLWYNCLREQNVLARENHLLKNIVGSTHDEFSELSNSIRTTMWQIRHVLNERELAYSASREFLQDESERKKFLDTLANDYFLNKDIPDDEVASMLTRFQLAIFGISETIQDNTVDINFIDGIKFLANLKLQRFKDSNDLISEISQEPITDVGESFILFTSDFEPHAVQEACVAIKDLRKSPDNKVPKLDELPTVRKYLKQLIHASSVEQATA
What are the official names of this protein?
54S ribosomal protein L4, mitochondrial, YmL4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: P20L1_RAT
Sequence: MSKKPPNRPGITFEIGARLEALDYLQKWYPSRIEKIDYEEGKMLVHFERWSHRYDEWIYWDSNRLRPLERPSLRKEGLKDEEDLFDFKAGEEVLARWTDCRYYPAKIEAINKEGTFTVQFYDGVIRCLKRMHIKAMPEDAKGQVKSQHPLSWCCPIDPAGSCNQSMGSEDWIALVKAAAAAAAKNKTGSKPRTSANSNKEKERDGGKWFKVPSKKAETSTCIVTAEIEKKEELPTSSEPFGLHIDSVPKIVFPQPESTLTNKRKNNQGNSFQAKRARLNKITGLLASKAVGVDGAEKKEDCSATAPVLEQAISPKPQSQKKNEAVISSSANTQKPALLSSTLSSGKARSKKCKHESGESSGCIKAPKSPLAPELIQAKDLTLVSQLSSVINKTSSPQPVNPPRPCKHSERRRRSQRLATLPMPDDSLEKLSSSSSATDGKVFSISSQNQQESSVPEVPAIAYVPLQKLGPCLPLDLSCGSEVTGSQAPDSSYPGGECPREEKEETPLFANPTSKVVSDVKGAAAATGILKTEKKVKLEEKTSTAFGKRKEKDKERKEKRDKDHYKPKQKKKKKKKKKSKQHDYSDYEDSSLDFLERCSSPLTRSSGSSLAPRSTFTEKTTTYQYPRAILSVDLSGENLSDVEFLDDSSTESLLLSGDEYNQDFDSTNFEESQDEDDALNEIVRCICELDEENGFMIQCEECLCWQHSVCMGLLEDSIPEQYICYICRDPPGQRWNAKYRYDKEWLNNGRMYGLSFVKENYSHLNAKKIVSTHHLLADVYGITEVLHGLQLKIGILKNKHHPDLRLWAYSGKRKDQDQVVAGAERKVILQDTANSEGRKYVQNHKEPPLKMEETYITSEHSYQKPQSFSQDCHSLTDPGSSDDDDVSSFEEDGELHVADNSHLLYSVKERGVSEKNPASENKVFVYNDKKGMEGPGDAHLQWQLNLLTHIENVQNEVTSRMDLIEKEVDVLESWLDFTGELEPPDPLARLPQLKRHIKQLLLDMGKVQQIATLCSV
What is the function of this protein?
Is a negative regulator of proteosomal degradation of a set of methylated proteins, including DNMT1 and SOX2 (By similarity).  Involved in the maintainance of embryonic stem cells pluripotency, through the regulation of SOX2 levels (By similarity).
What are the official names of this protein?
PHD finger protein 20-like protein 1.
Protein: HIR1_CANAL
Sequence: MQILKIPWFGHKTENKTVECYAVTINKDGTRLASGGLDGNVKIWDLTTINVFYKMADQPHKSKKDSTSTKLEESLPDKSLRRPLCSMSRHNGVVTSLKFSPDGRWLASGSDDKICLIWEKDNTQIAKSFGTDEHDLEHWTVRKRLVAHDNDIQDICWSPDGNLLVTVGLDRSVIIWNALTFEKIKRYDIHQSMVKGIVFDPANKFFATASDDRTVRIFRYYKKLNEYNNYEFQMEHVVVDPFKKSPLTSYFRRMSWSPDGQHIAVPNATNGPVPSVAIINRGNWGSDISLIGHEAPVEVCSFSPTLFQIADTPANEEIKFQTVVATGGQDRTLAIWSTCNSRPIVVCSDIVDSSITDICWSPDGETLYFSCLDGSITGVKFGARELGQPVKEDLIDQQLNRYGADRESTILPESVEQLQLEEQSKDSRAISIRRMMPIQEAKPEQTPPISTPASAAIDIERLRKQTVTMTKSGKKRVAPLLVSTSAAPKNVLQKPLEKKRRTKSSSKISQAAYLLPKMGVQTTVHGIKKKAESMSNDTEVEENNDNDDIGENVMANTNSVSDAALKRQRNRRKRKLMELKYPSSFKYISNLPEGLFNNHTLQNIEINKIYKAHSKHKDISAEISSSTAVEIDEDLVFSVVFRVFDHMRKENEVLGQTSGRIRTTIEVRNGKPWDDDISDRDFDDATKVIVTEEGNDKREYCLFFPFRVQHVLPIILNDVLKYYVLCSFHGSVQIISADTGSYRCPTFELGESVVTMRHSQGYMLVLTSSGLFYSWDLKAMKVTMTGISIAAILNNYEIGGKIVVSPIVRGLEINPQDGSPLVLLDMTNDIYGYSIDLQCWVKTVDSWYYGVGADKDLDVVLTGLVKKSKMSYEEDKVTEKIFTYKFDSSNDLEDAMRKRGQELLDLI
What is the function of this protein?
Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.
What are the official names of this protein?
Protein HIR1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat HIR1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PER_COPC7
Sequence: MKLSLLSTFAAVIIGALALPQGPGGGGSVTCPGGQSTSNSQCCVWFDVLDDLQTNFYQGSKCESPVRKILRIVFHDAIGFSPALTAAGQFGGGGADGSIIAHSNIELAFPANGGLTDTIEALRAVGINHGVSFGDLIQFATAVGMSNCPGSPRLEFLTGRSNSSQPSPPSLIPGPGNIVTAILDRMGDAGFSPDEVVDLLAAHSLASQEGLNSAIFRSPLDSTPQVFDTQFYIETLLKGTTQPGPSLGFAEELSPFPGEFRMRSDALLARDSRTACRWQSMTSSNEVMGQRYRAAMAKMSVLGFDRNALTDCSDVIPSAVSNNAAPVIPGGLTVDDIEVSCPSEPFPEIATASGPLPSLAPAP
What are the official names of this protein?
Peroxidase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Ligninase subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MPIP3_MESAU
Sequence: MSTGPFPSSRREESSVSAPSFRFSQRKMLNLLLERNTSFTQDFPRSPGDKLLDSTNLSILSGGTPKRCLDLSNLSNGEMSASPLITSADFDDTGSLDSSGPQDVQLTEKNHHQDPMKGIPVQLLCSTPNALDHSHRKKDAVRGLSANKENINTNLKTLQWESPRIPRFQNTPGDPLASPLPLLGNGVSMDTEVRSLGSPITAVPKLSKNLNLEDQEEISEEPMEFSLEDHDTKECVLPTVSGKHQDLKYITPDTVAALLSGKFQGLIEKFYIIDCRYPYEYLGGHILGAINLCSQKELHEFFLKKPIVPLDIQKRVIIVFLCEFSSERGPRMCRSLRRKDRALNQYPALYYPELYILKGGYRDFFPEYTELCEPQGYCPMHHQDHQAELLMWRNQSKAQEGERQLSEQIALLMKKGVSLP
What is the function of this protein?
Functions as a dosage-dependent inducer in mitotic control.  Tyrosine protein phosphatase required for progression of the cell cycle.  Directly dephosphorylates CDK1 and activates its kinase activity.  When phosphorylated, highly effective in activating G2 cells into prophase (By similarity).
What are the official names of this protein?
M-phase inducer phosphatase 3, Dual specificity phosphatase Cdc25C.
What is the protein family that this protein belongs to?
Belongs to the MPI phosphatase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPA_BIGNA
Sequence: MLNIATDEICSLIRYRIQNYNSELKLNNVGVVFKVGDGIVRVFGLQGAMAGELLLFEEGSVGIAFNLEKNNIGVVLLGDCTLIQEGMIVKGTGKIGEVPVGDKFLGRIVDSLANPIDGKGDIVSSQTRLIEPPAPGIVDRRSVYEPLQTGITAIDAMIPIGRGQRELIIGDRQTGKTAVAIDTILNQKGKDVKCVYVAVGQKSSSIAQVVTTLQDKGALDYTILVSAAADTTATMQYIAPYSGTALAEYFMYNGSHALVVYDDLSKQAQAYREMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDSLGGGSLTALPIVETQEGDVSAYIPTNVISITDGQIFLSSDIFNAGFRPAINVGISVSRVGSAAQPKAMKRVAGKLKLELAQFAELEAFSQFASDLDQATQNQLARGKRLREILKQPQYSPLSLENQVGIIFAGTNGYLDKVSIENIPSYITSLTESLKNEKSKFGDVILSTKDFTKDEENVLRNILEAS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, chloroplastic, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: ISDB_STAAB
Sequence: MNKQQKEFKSFYSIRKSSLGVASVAISTLLLLMSNGEAQAAEETGGTNTEAQPKTEAVASPSTTTEKAPEAKSVANAVSVSNKEVEAPTSETKEVKPAAKSDNNTYPILNQELREAIKNPAIKDKDHSAPNSRPIDFEMKKENGEQQFYHYASSVKPARVIFTDSKPEIELGLQSGQFWRKFEVYEGDKKLPIKLVSYDTVKDYAYIRFSVSNGTKAVKIVSSTHFNNKEEKYDYTLMEFAQPIYNSADKFKTEEDYKAEKLLAPYKKAKTLERQVYELNKIQDKLPEKLKAEYKKKLEETKKALDEQVKSAITEFQNVQPTNEKMTDLQDTKYVVYESVENNESMMDTFVKHPIKTGMLNGKKYMVMETTNDDYWKDFMVEGQRVRTISKDAKNNTRTIIFPYVEGKTLYDAIVKVHVKTIDYDGQYHVRIVDKEAFTKANADKTNKKEQQDNSAKKETTPATPSKPTTPPVEKESQKQDSQKDDNKQSPSVEKENDASSESGKDKTPATKPAKGEVESSSTTPTKVVSTTQNAAKPTTASSETTKDVVQTSAGSSEAKDSAPLQKANIKNTNDGHTQSENNKNTQENKAKSLPQTGEESNKDMTLPLMSLLALSSIIAFVLPRKRKN
What is the function of this protein?
Cell wall-anchored surface receptor that extracts heme from oxidized metHb to enable growth on hemoglobin as a sole iron source.  Rapidly extracts heme from hemoglobin and transfers it to IsdA or IsdC, which then relays it to the membrane transporter/IsdEF for internalization.  Promotes also resistance to hydrogen peroxide and killing by neutrophils.
What are the official names of this protein?
Iron-regulated surface determinant protein B, Fur-regulated protein B, Staphylococcal iron-regulated protein H, Staphylococcus aureus surface protein J.
What is the protein family that this protein belongs to?
Belongs to the IsdB family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor. Note=Anchored to the cell wall by sortase A.
Protein: RL29_DESVM
Sequence: MNAAELRKLSAEQLKDKLAESRKELFDMRFRHATAQLEKTSNLPATKRDIARILTILKEKG
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: WDR46_CANLF
Sequence: METASKPGRDVQPKKARLQTKKKKPRRYWEKEATLTAAGASPGPPRNKKRNRELRPQRPKNINLPKKSRIPGKPQFPKKPREQRNLEPQRNLSGAQDPFPGPAPIPEEVARKFRRIDKSKKLPHSKSKTRSRLEVAEAEEEEISIKAARSELLLAEEPGFLEGEDGEDTAKIRQAEIVEAVDIASAAKHFDLNLRQFGPYRLNYSPVGRHLAFGGHRGHVATLDWVTKRLMCEINVMEAVRDIRFLHSEALFAVAQNRWLHIYDNQGIELHCIRRCDRVTRLEFLPFHFLLATASETGFLTYLDVSVGKIVAALNARAGRLDVMTKNPYNAVIHLGHSNGTVSLWSPAMKEPLAKILCHRGGVRAVAVDSTGTYMATSGLDHQLKIFDLRGMFQPLSARTLPQGAGHLAFSQRGLLAAGMSDVVNIWMGQGMASPPSLEQPYLTHRLSGHVHGLHFCPFEDVLGLGHSGGITSMLVPGAAEPNFDGLENNPYRSQKQRQEWEVKALLEKVPAELICLDPRALAEVDVISLEQEKKERIERLGYDPEAKAPFQPKPKQKGRSSTASLVKRRRKVMDKEHRDKVRQSLEQQPQKQEKKAKPLKARPSALDRFVR
What is the function of this protein?
Scaffold component of the nucleolar structure.  Required for localization of DDX21 and NCL to the granular compartment of the nucleolus.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
WD repeat-containing protein 46.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RL29_ACIBT
Sequence: MKTKDLREKSVEELKALLDEQQLNQFRLRMAKATGQLGKSHEVQVARKTIARIKTLLTEKQGNGQ
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: TRI39_PANTR
Sequence: MAETSLLEAGASAASTAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTSRYRSLRPNRQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYEDQEAVCLICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEGKCLQSGFEMLKDVKSTLEKNIPRKFGGSLSRICPRDHKALLGLVKEINRCEKVKTMEVTSVSIELEKNFSNFPRQYFALRKILKQLIADVTLDPETAHPNLVLSEDRKSVKFVETRLRDLPDTPRRFTFYPCVLATEGFTSGRHYWEVEVGDKTHWAVGVCRDSVSRKGELTPLPETGYWRVRLWNGDKYAATTTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVTDRSHIYTFTDTFTEKLWPLFYPGIRAGRKNAAPLTIRPPTDWE
What is the function of this protein?
E3 ubiquitin-protein ligase (By similarity).  May facilitate apoptosis by inhibiting APC/C-Cdh1-mediated poly-ubiquitination and subsequent proteasome-mediated degradation of the pro-apoptotic protein MOAP1 (By similarity).  Regulates the G1/S transition of the cell cycle and DNA damage-induced G2 arrest by stabilizing CDKN1A/p21 (By similarity).  Positively regulates CDKN1A/p21 stability by competing with DTL for CDKN1A/p21 binding, therefore disrupting DCX(DTL) E3 ubiquitin ligase complex-mediated CDKN1A/p21 ubiquitination and degradation (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase TRIM39, RING-type E3 ubiquitin transferase TRIM39, Tripartite motif-containing protein 39.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Mitochondrion. Nucleus. Note=Found predominantly in the cytosol. Partial shift from the cytosol to the mitochondria when colocalized with MOAP1. Colocalizes with CDKN1A in the nucleus.