PharMolix/UniProtQA huggingface dataset:
Protein: PYRC_NEIM0
Sequence: MQTLTIIRPDDMHLHLRDGDALKAVVPYTARQMGRAVIMPNLKPPVVSVADALAYKARIMAALPEGSAFEPLMTLYLTDNATSELVREAKAAGIVAFKLYPAGATTNSDSGVTDLFKLIPVLEEMAKQGILFLVHGEVTDPEIDIFDREAAFIGRVMKPVLAQVPNLKVVFEHITTAEAARLVLEAGDNVAATVTPQHLLLNRNDLLVGGVRPHHFCLPVLKRETHRQALVAAVTGEKAHKFFLGTDSAPHAKSAKENACGCAGMFSAMTAVELYAEVFEKAGALDKLEAFASKNGARFYGIPENAGTITLVKQSQTVPASVPYGDGELVPMRAGGEIGWTVQY
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: DJC10_HUMAN
Sequence: MGVWLNKDDYIRDLKRIILCFLIVYMAILVGTDQDFYSLLGVSKTASSREIRQAFKKLALKLHPDKNPNNPNAHGDFLKINRAYEVLKDEDLRKKYDKYGEKGLEDNQGGQYESWNYYRYDFGIYDDDPEIITLERREFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFAKEVDGLLRIGAVNCGDDRMLCRMKGVNSYPSLFIFRSGMAPVKYHGDRSKESLVSFAMQHVRSTVTELWTGNFVNSIQTAFAAGIGWLITFCSKGGDCLTSQTRLRLSGMLDGLVNVGWMDCATQDNLCKSLDITTSTTAYFPPGATLNNKEKNSILFLNSLDAKEIYLEVIHNLPDFELLSANTLEDRLAHHRWLLFFHFGKNENSNDPELKKLKTLLKNDHIQVGRFDCSSAPDICSNLYVFQPSLAVFKGQGTKEYEIHHGKKILYDILAFAKESVNSHVTTLGPQNFPANDKEPWLVDFFAPWCPPCRALLPELRRASNLLYGQLKFGTLDCTVHEGLCNMYNIQAYPTTVVFNQSNIHEYEGHHSAEQILEFIEDLMNPSVVSLTPTTFNELVTQRKHNEVWMVDFYSPWCHPCQVLMPEWKRMARTLTGLINVGSIDCQQYHSFCAQENVQRYPEIRFFPPKSNKAYHYHSYNGWNRDAYSLRIWGLGFLPQVSTDLTPQTFSEKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIKGKVKAGKVDCQAYAQTCQKAGIRAYPTVKFYFYERAKRNFQEEQINTRDAKAIAALISEKLETLRNQGKRNKDEL
What is the function of this protein?
Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins.  Required for efficient folding of proteins in the endoplasmic reticulum by catalyzing the removal of non-native disulfide bonds formed during the folding of proteins, such as LDLR.  Also involved in endoplasmic reticulum-associated degradation (ERAD) by reducing incorrect disulfide bonds in misfolded glycoproteins recognized by EDEM1.  Interaction with HSPA5 is required its activity, not for the disulfide reductase activity, but to facilitate the release of DNAJC10 from its substrate.  Promotes apoptotic signaling pathway in response to endoplasmic reticulum stress.
What are the official names of this protein?
DnaJ homolog subfamily C member 10, Endoplasmic reticulum DNA J domain-containing protein 5, ER-resident protein ERdj5, ERdj5, Macrothioredoxin, MTHr.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: RPOB_PROM3
Sequence: MSSSAIQVAKTATYLPDLVEVQRASFKWFLDEGLIEELDSFSPITDYTGKLELHFVGNEYRLKRPRHDVEEAKRRDATFASQMYVTCRLVNKETGEIKEQEVFIGELPLMTERGTFIINGAERVIVNQIVRSPGVYFKDEQDKNGRRTYNASVIPNRGAWLKFETDKNDLLHVRVDKTRKINAHVLMRAMGLSDNDVIDKLRHPEYYKKSIEAANEEGISSEDQALLELYKKLRPGEPPSVSGGQQLLQTRFFDPKRYDLGRVGRYKINKKLRLTIPDTVRTLTHEDVLSTLDYLINLELDVGGASLDDIDHLGNRRVRSVGELLQNQVRVGLNRLERIIKERMTVGETDSLTPAQLVNPKPLVAAVKEFFGSSQLSQFMDQTNPLAELTHKRRISALGPGGLTRERAGFAVRDIHPSHYGRLCPIETPEGPNAGLINSLATHARVNQYGFIETPFWKVENGRLIKEGDPIYLSADLEDECRVAPGDVATDADGQILAELIPVRYRQDFEKVPPEQVDYVQLSPVQVISVATSLIPFLEHDDANRALMGSNMQRQAVPLLRPERPLVGTGLETQVARDSGMVPISRVNGMVTFVDATAIIVRDEDGVDHTHYLQKYQRSNQDTCLNQRPIVCQGDPVIVGQVLADGSACEGGEIALGQNVLVAYMPWEGYNYEDAILVSERLVKDDLYTSVHIEKYEIEARQTKLGPEEITREIPNVAEESLGNLDEMGIIRIGAFVESGDILVGKVTPKGESDQPPEEKLLRAIFGEKARDVRDNSLRVPSTERGRVVDVRIYTREQGDELPPGANMVARVYVAQRRKIQVGDKMAGRHGNKGIISRILPREDMPFLPDGTPVDIVLNPLGVPSRMNVGQVFECLMGWAAANLDCRVKVVPFDEMYGAEKSQQTVEAYLKEAAKQPGKEWVYNPENPGKLQLIDGRSGEPFDQPVTVGYAQILKLVHLVDDKIHARSTGPYSLVTQQPLGGKAQQGGQRLGEMEVWALEAYGAAYTLQELLTVKSDDMQGRNEALNAIVKGKPIPRPGTPESFKVLMRELQSLGLDIAVYTDEGKEVDLMQDVNPRRSTPSRPTYESLGVADYDED
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: RL20_LEUCK
Sequence: MRVKGGTVSRARRKKMVKLAKGYRGQRRINFKVAKQQVWKSYLYAYRDRKNTKRNFRKLWIARINAAARMNGLSYSKLMHGLTLAGVELNRKMLAEIAVTDFDTFAKLADQAKAALASDNVLVQERVAATLETTVKVDR
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: RL33_CLAM3
Sequence: MAKQQDVRPIIKLRSTAGTGYTYVTRKNRRNNPDRLVLKKYDPVVRKHVDFREER
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: ISPT_BACTN
Sequence: MSYIEKIDKNRIPQHIAIIMDGNGRWAKQRGKERTYGHQAGAETVHKIIEDAARLGVKYLTLYTFSTENWNRPQEEVAALMNLLVDSIEEETLMKNNIRFRIIGDIKKLPAEVQEGLSRCIEHTANNTGTCLVLALSYSSRWEMTEAVRQIATLAKTGEISPEQITDEYITAHLTTNFMPDPDLLIRTGGEIRLSNYLLWQCAYSELYFCDTFWPDFDKEEFCKAIYEYQQRERRFGKTSEQIS
What is the function of this protein?
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
What are the official names of this protein?
Isoprenyl transferase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: LPXB_ECODH
Sequence: MTEQRPLTIALVAGETSGDILGAGLIRALKEHVPNARFVGVAGPRMQAEGCEAWYEMEELAVMGIVEVLGRLRRLLHIRADLTKRFGELKPDVFVGIDAPDFNITLEGNLKKQGIKTIHYVSPSVWAWRQKRVFKIGRATDLVLAFLPFEKAFYDKYNVPCRFIGHTMADAMPLDPDKNAARDVLGIPHDAHCLALLPGSRGAEVEMLSADFLKTAQLLRQTYPDLEIVVPLVNAKRREQFERIKAEVAPDLSVHLLDGMGREAMVASDAALLASGTAALECMLAKCPMVVGYRMKPFTFWLAKRLVKTDYVSLPNLLAGRELVKELLQEECEPQKLAAALLPLLANGKTSHAMHDTFRELHQQIRCNADEQAAQAVLELAQ
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: TNAA_VIBVY
Sequence: MDNFKHLPEPFRIRVIEPVKRTTREYREEAILKAGMNPFLLDSEDVFIDLLTDSGTGAITQDMQAAMFRGDEAYSGSRSYHALANAVKDIFGYEFTIPTHQGRGAEQIYIPVLIKKREIEKGLDRSKMVALSNYFFDTTQGHTQINCCVAKNVYTEEAFDTGVKADFKGNFDLEKLEEAILEAGPANVPYIVSTITCNSAGGQPVSLANLKAVYEIAKRYDIPVIMDSARFAENAYFIQQREKDYQNWSIEEITRESYKYADGLAMSAKKDAMVQMGGLLCFKDESFLDVYTECRTLCVVQEGFPTYGGLEGGAMERLAVGLYDGMRQDWLAYRINQVEYLVNGLESIGVVCQQAGGHAAFVDAGKLLPHIPADQFPAHALACELYKVAGIRAVEIGSLLLGRDPATGKQHPCPAELLRLTIPRATYTQTHMDFIIEAFGKVKANAANVKGLEFTYEPQVLRHFTARLKEIDA
What are the official names of this protein?
Tryptophanase, L-tryptophan indole-lyase, TNase.
What is the protein family that this protein belongs to?
Belongs to the beta-eliminating lyase family.
Protein: NSS_BUNLC
Sequence: MMSHQQVQMDLILMQGIWTSVLKMQNHSTLLQLGSSSSMPQRPRLLSRVSQRGRLTLNLESGRWRLSIIIFLETGTTQLVTTILPSTDYLGI
What is the function of this protein?
Inhibits host transcriptional machinery, by producing modifications to the phosphorylation state of the C-terminal domain (CTD) of RNA polymerase II.  Inhibits phosphorylation at serine 2 in the heptapeptide repeat (YSPTSPS) of the CTD of RNA polymerase II, suggesting that the elongation step of transcription and/or 3'-end processing is prevented.  Inhibition of host transcription machinery leads to shut off of host cell protein synthesis and inhibition of the host innate immune response.  NSs also seems to be involved in the nuclear relocalization of host PABP1 (By similarity).
What are the official names of this protein?
Non-structural protein NS-S.
What is the protein family that this protein belongs to?
Belongs to the orthobunyavirus NS-S protein family.
Protein: BETB_PSEAE
Sequence: MARFEEQKLYIGGRYVEASSGATFETINPANGEVLAKVQRASREDVERAVQSAVEGQKVWAAMTAMQRSRILRRAVDILRERNDELAALETLDTGKPLAETRSVDIVTGADVLEYYAGLVPAIEGEQIPLRETSFVYTRREPLGVVAGIGAWNYPVQIALWKSAPALAAGNAMIFKPSEVTPLTALKLAEIYTEAGVPDGVFNVLTGSGREVGQWLTEHPLIEKISFTGGTSTGKKVMASASSSSLKEVTMELGGKSPLIIFPDADLDRAADIAVMANFFSSGQVCTNGTRVFIHRSQQARFEAKVLERVQRIRLGDPQDENTNFGPLVSFPHMESVLGYIESGKAQKARLLCGGERVTDGAFGKGAYVAPTVFTDCRDDMTIVREEIFGPVMSILVYDDEDEAIRRANDTEYGLAAGVVTQDLARAHRAIHRLEAGICWINTWGESPAEMPVGGYKQSGVGRENGLTTLAHYTRIKSVQVELGDYASVF
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.  In P. aeruginosa this reaction is a compulsory step in the assimilation of carbon and nitrogen when bacteria are growing in choline or choline precursors.  Can use NADP(+) with similar efficiency to NAD(+), a property that can be used by the bacterium to produce the NADPH needed to combat the oxidative stress imposed by the host defenses.
What are the official names of this protein?
NAD/NADP-dependent betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: PTH_STAA3
Sequence: MKCIVGLGNIGKRFELTRHNIGFEVVDYILEKNNFSLDKQKFKGAYTIERMNGDKVLFIEPMTMMNLSGEAVAPIMDYYNVNPEDLIVLYDDLDLEQGQVRLRQKGSAGGHNGMKSIIKMLGTDQFKRIRIGVGRPTNGMTVPDYVLQRFSNDEMVTMEKVIEHAARAIEKFVETSRFDHVMNEFNGEVK
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_BRUME
Sequence: MGKAKAPRQLKDNEAKAVARTLRVSPQKLNLVASMIRGKKVNAALADLTFSRKRIAGTVKKTLESAIANAENNHDLDVDALIVAEAYVGKSIVMKRFHVRDRGRASRIEKPFSHLTIVVREVAEKGKAA
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: BIOD_BRUO2
Sequence: MNSRLIVTGTDTGIGKTVFSAALCHALGAAYWKPVQSGLEEETDSEIVARLAQASPQRILPEAWRLNTPASPHLSARLDGVEIRPEEMHIPATSLPLVIEGAGGLLVPLNDKTLFADLFAIWRIPAILCARAALGTINHTLLSLEAMRSRDIPVLGVAFIGEANEDTETTIAHLGRVKRLGRLPLLDDLSPEKLHHSFARNFHIDDFAGVAR
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARFB_METFA
Sequence: MELRLSSGNILDEKVHKVGIIALGSFLENHGAVLPIDTDIKIASYIALKAAILTGAKFLGVVIPSTEYEYVKHGIHNKPEDIYYYLRFLINEGKKIGVEKFLIVNCHGGNILIEKFLKDLEYEFGVKVEMINIAFTHAATEEVSVGYVIGIAKADEKSLKEHNNFEKYPEVGMVGLKEARENNKAIDEEAKAVEKFGVRLDKNLGEKILNDAIEKVVDKVKEMIR
What is the function of this protein?
Catalyzes the hydrolysis of the formamide of 2-amino-5-formylamino-6-ribosylamino-4(3H)-pyrimidinone 5'-monophosphate (FAPy) to form 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (APy).
What are the official names of this protein?
2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5'-monophosphate deformylase, FAPy deformylase, Formamide hydrolase.
What is the protein family that this protein belongs to?
Belongs to the creatininase superfamily. FAPy deformylase family.
Protein: FABA_BRUA4
Sequence: MAEQKSSYGYEELLACARGEMFGPGNAQLPLPPMLMVHRITDISETGGEFDKGYIRAEYDVRPDDWYFPCHFMGNPIMPGCLGLDGMWQLTGFFLGWLGEPGRGMALSTGEVKFKGMVRPHTKLLEYGIDFKRVMRGRLVLGTADGWLKADGETIYRASDLRVGLSKDSEGQ
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_BARBK
Sequence: MTNKKVVVLVAGGTGGHLFPAEALAVELRQRGYDVHLATDERAKRFVRHFDEKHIHIISSATLVRHHPFALIKTFWLLLRGMVQSWILFRKLRPVLVGGFGGYPTVPPVWVAALTGRVTFIHEQNAVMGRANRVLATRVNAIASGLLLENKIHIHKTFVTGNPVREAILKAAEIPYCASTSKQPFYFLVFGGSQGASAFSRIVPEAVKLLDHDIRERLHIVQQVRGEEIDLAKIYQDMGVQAEVAPFFDNMVEHIARSHFIMSRAGASTVCEIAIIGRPALLIPYPHALDHDQAANAALLAARGGAQIMLEKDLNAQILSSLLTKFCCEPHSLEQRALAAKKVGKPQATRVLADMAEALIVGRSLLDMKREFFDENTT
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RSGA_HALH5
Sequence: MPKGTIVKALSGFYYVQNEDGLFQCRGRGNFRNRNIKPLVGDEVVFEAENKTDGYVLEIMERKNELLRPPIANVDRAILVFSAAEPTFSPLLLDRFLVHVEANGIEPLIVISKIDLLTEEELETIKQYRNDYEQLGYKVYLTSTIEQLGLDAIRKEFDDHVSVIAGQSGVGKSSLLNAINPALDIETNQISSHLGRGKHTTRHVELIPFGSGLVADTPGFSSLDFIDMEPEELSHYFPEMRDRLPSCKFRGCTHTQEPKCAVKEALAQGEIREFRYEHYVTFLEEVKTQHKRRF
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
Protein: DLTC_LACCB
Sequence: MADEAIKNGVLDILADLTGSDDVKTNLDLNLFETGLLDSMGTVQLLLELQSQFGVEAPVSEFDRSQWDTPNKIIAKVEQAQ
What is the function of this protein?
Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA).  The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA.  The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanyl carrier protein, DCP, D-alanine--poly(phosphoribitol) ligase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the DltC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PXPA_VIBCM
Sequence: MSKRTIQLNCDMGESFGVWTMGADEEVMPWIDMANIACGFHASDPHVMSRTIDLALEHEVMIGAHPSYPDLQGFGRRSLAMNEQEVSEIILYQVGALKALCESKNGQLSYVKPHGALYNDMMSDPSIFRAVVDAVSCFNLPLMVLASANNQDYLDIADRFDVPLLFEAFADRTYLANGKLTPRSQPNAVLSSEEAILNQVRQIARYGKVTSSDGFVIPIEADTLCVHGDNPNAVSLIARIRAALDE
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: KTHY_PSEPW
Sequence: MFITLEGPEGAGKSTNRDYLAARLREQGLDVVLTREPGGTPLAEKVRELLLAPSDEVMAADTELLLVFAARAQHLAQVIRPALARGAVVLCDRFTDATYAYQGGGRGLSVERIAALEQFVQGELRPDLTLVFDLPVEVGLARAAARGRLDRFEQEGQAFFEAVRQAYLQRARREPQRYDLLDAAQPLEAVQRAIDALLPGILERCRG
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: IHFB_PARPJ
Sequence: MTKSELVAQLAARFPQLVLKDADFAVKTMLDAMSEALANGHRIEIRGFGSFGLNRRPSRVGRNPKSGEKVLVPEKYVPHFKPGKELRERVDRRAGEPLKAEEPDDDL
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: PPX_ECOLI
Sequence: MPIHDKSPRPQEFAAVDLGSNSFHMVIARVVDGAMQIIGRLKQRVHLADGLGPDNMLSEEAMTRGLNCLSLFAERLQGFSPASVCIVGTHTLRQALNATDFLKRAEKVIPYPIEIISGNEEARLIFMGVEHTQPEKGRKLVIDIGGGSTELVIGENFEPILVESRRMGCVSFAQLYFPGGVINKENFQRARMAAAQKLETLTWQFRIQGWNVAMGASGTIKAAHEVLMEMGEKDGIITPERLEKLVKEVLRHRNFASLSLPGLSEERKTVFVPGLAILCGVFDALAIRELRLSDGALREGVLYEMEGRFRHQDVRSRTASSLANQYHIDSEQARRVLDTTMQMYEQWREQQPKLAHPQLEALLRWAAMLHEVGLNINHSGLHRHSAYILQNSDLPGFNQEQQLMMATLVRYHRKAIKLDDLPRFTLFKKKQFLPLIQLLRLGVLLNNQRQATTTPPTLTLITDDSHWTLRFPHDWFSQNALVLLDLEKEQEYWEGVAGWRLKIEEESTPEIAA
What is the function of this protein?
Degradation of inorganic polyphosphates (polyP).  Releases orthophosphate processively from the ends of the polyP chain.  Has a strong preference for long-chain polyphosphates and has only weak affinity for smaller size polyP of about 15 residues.
What are the official names of this protein?
Exopolyphosphatase, ExopolyPase, Metaphosphatase.
What is the protein family that this protein belongs to?
Belongs to the GppA/Ppx family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CCME_HYPNA
Sequence: MRARTRRLYTFGIAAALIVAAAALAFFALRENANLFYTPEVLAEKGLPREGREVKVGGWVEPGSLTYADGGATMRFTVIDNSPSTITVSFNGVAPDLFREGQGVVATGTFTPEGEFTARQLLAKHDENYQPRELKPLEAGG
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: Y852_CHLTR
Sequence: MLHSLFRLTLLFYALFNALGSLPVFIALLKNFSFKKQQHIILRESIFALLLLLLFVTFGRGFFRLLGIILPAFQFTGSLLLGSIAIDMMKALPPQTETLERDKDEPIFFPLAFPVITGPAMITSTLGHMEEGIFPKKIVLGAIVLAWLFSLITLLLSSSINRLFGQMGLLALERLFGISLALMAGNLMLKALSTAFNIGYYVTP
What are the official names of this protein?
UPF0056 membrane protein CT_852.
What is the protein family that this protein belongs to?
Belongs to the UPF0056 (MarC) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KDSA_BRASB
Sequence: MTTAATAAAIVTAGSVRFGNDLPLAVIAGPCQLESRGHALEVASALKEIATRLNIGLVYKTSFDKANRTSGSAARGLGLAQSLPIFAEIRSSLGLPVLTDIHDASQCAEVAQAVDVLQIPAFLCRQTDLLLAAAATGKVVNVKKGQFLAPWDMANVVAKITGAGNPNVLATERGVSFGYNTLISDMRSLPIMARTTGAPVIFDATHSVQQPGGQGTSSGGQREFVPVLARAAVAVGVAGVFIETHPDPDHAPSDGPNMVPLAEFEGLLRRLMAFDKLAKAPATDTR
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCLJ_BACSU
Sequence: MKILMIEDNVSVCTMTEMFFFKEGFEAEFVHDGLEGYQRFTEENWDLIILDIMLPSMDGVTICRKIRETSTVPIIMLTAKDTESDQVIGFEMGADDYVTKPFSPLTLVARIKAVIRRYKATGKAVIDEDMIETECFTINKKTREVLLNGEPVENLTPKEFDLLYYLVQNPRQVFSREQLLEQVWGYQFYGDERTVDVHIKRLRKKLASEDKPFLYTVWGVGYKFDED
What is the function of this protein?
Could be member of the two-component regulatory system YclK/YclJ.
What are the official names of this protein?
Uncharacterized transcriptional regulatory protein YclJ.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BRNQ_SALTY
Sequence: MTHQLKSRDIIALGFMTFALFVGAGNIIFPPMVGLQAGEHVWTAAIGFLITAVGLPVLTVVALAKVGGGVDSLSTPIGKVAGLLLATVCYLAVGPLFATPRTATVSFEVGIAPLTGDSAMPLLIYSVVYFAIVILVSLYPGKLLDTVGNFLAPLKIIALVILSVAAIVWPAGPISNALDAYQNAAFSNGFVNGYLTMDTLGAMVFGIVIVNAARSRGVTEARLLTRYTVWAGLMAGVGLTLLYLALFRLGSDSATLVDQSANGAAILHAYVQHTFGGAGSFLLAALIFIACLVTAVGLTCACAEFFAQYIPLSYRTLVFILGGFSMVVSNLGLSHLIQISIPVLTAIYPPCIALVVLSFTRSWWHNSTRIIAPAMFISLLFGILDGIKASAFGDMLPAWSQRLPLAEQGLAWLMPTVVMVILAIIWDRAAGRQVTSSAH
What is the function of this protein?
Liv-II branched chain amino acid transport system, which transports leucine, valine and isoleucine.
What are the official names of this protein?
Branched-chain amino acid permease BrnQ, BCAA permease, Branched-chain amino acid transport system 2 carrier protein, LIV-II.
What is the protein family that this protein belongs to?
Belongs to the branched chain amino acid transporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RPPH_LEGPA
Sequence: MVIDRAGYRLNVGIILVNDSDRVFWGRRSGHDAWQFPQGGLAPGETAMQAMYRELHEEVGLDKGDVEILGSTRRWLKYRLPKQYLRHGSEPLVIGQKQKWYLLKLVTSEQKVRLDLSDSPEFDSWRWVDFHEPEQQVIFFKRQVYIQALKELEPLLKKERRTPYGLKRKRGNQRA
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: FENR_RHORT
Sequence: MSQSTPLRTDVVVIGAGPVGLSAVFQCGMLKLRCHVVDALEAPGGQLTALYPEKPIYDVPGFPSIPAGELIDRLLEQVAPFTPEFHLSQQVIALEAVAGAEPAAWRLTTSRGVVLEAAAVIIAAGAGAFGPNRPPLDRLEAFEGTSVFYMVSKREAFRGRKVVIAGGGDSAVDWAISLSDVAERVHVVHRRPKFRCAPESAARLDQLAAEGKIDLVIPYQLKALGGTEGRLESVTVADLDGAERQLDADVLLPFFGLAANLGPIAEWGLGVERQTIPVTQATCRTARPGIYAVGDVASYPGKLKLILTGFAEASAAAHNAFHDCRPGEALHFEHSTTTGVPGIPA
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.