PharMolix/UniProtQA huggingface dataset:
Protein: RL2_DESAL
Sequence: MAVRKTKPTSPGRRFQEFGTFEEITKKKPEKSLIKVVKKSGGRNANGRVTCRHRGGGSRRQLRIVDFKRNKTGIPAKVAAIEYDPNRGARLALLHYVDGEKRYIIAPVNLTVGDMVESGPEADIKPGNALPLNNIPLGTQIHNIELKVGKGGQVVRGAGTFAQLVAKEGKYAQVRLPSGEVRLVLLKCMATIGQVGNVEHENLALGKAGRKRWLGRRPSVRGVAMNPVDHPMGGGEGRSSGGRHPCSPWGMPTKGYKTRKNKTTDKFIVRKRNKR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: FTHS_STRA1
Sequence: MKTDIEIAQSVALKPIAEIVEQVGIGFDDIELYGKYKAKLSFDKIEAVRSQKVGKLILVTAINPTPAGEGKSTMSIGLADALNKIGKKTMIALREPSLGPVMGIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELDIDQRRVIWKRVVDLNDRALRQVIVGLGSPVNGIPREDGFDITVASEIMAILCLATDLSDLKKRLSNIVVAYSRDRKPIYVKDLKIEGALTLILKDAIKPNLVQTIYGTPALVHGGPFANIAHGCNSVLATSTALRLADYVVTEAGFGADLGAEKFLDIKTPNLPTSPDAIVIVATLRALKMHGGVSKEDLSQENVEAVKRGFTNLERHVNNMRQYGVPVVVAINQFTADTESEIATLKTLCSNIDVAVELASVWEDGADGGLELAQTVANVIETQSSNYKRLYNDADTIEEKIKKIVTKIYGGNKVHFGPKAQIQLKEFSDNGWDKMPICMAKTQYSFSDNPNLLGAPTDFDITVREFVPKTGAGFIVALTGDVLTMPGLPKKPAALNMDVLEDGTAIGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: HIS8_MYCBO
Sequence: MTRSGHPVTLDDLPLRADLRGKAPYGAPQLAVPVRLNTNENPHPPTRALVDDVVRSVREAAIDLHRYPDRDAVALRADLAGYLTAQTGIQLGVENIWAANGSNEILQQLLQAFGGPGRSAIGFVPSYSMHPIISDGTHTEWIEASRANDFGLDVDVAVAAVVDRKPDVVFIASPNNPSGQSVSLPDLCKLLDVAPGIAIVDEAYGEFSSQPSAVSLVEEYPSKLVVTRTMSKAFAFAGGRLGYLIATPAVIDAMLLVRLPYHLSSVTQAAARAALRHSDDTLSSVAALIAERERVTTSLNDMGFRVIPSDANFVLFGEFADAPAAWRRYLEAGILIRDVGIPGYLRATTGLAEENDAFLRASARIATDLVPVTRSPVGAP
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: LEUC_SALRD
Sequence: MSTGTLYDKVWNRHAVRELPTGETQLFVGLHLIHEVTSPQAFGMLEERDLSVAFPARTFATTDHIIPTADLERPFGDDQAETMLQVLERNTEAYDITFFDPSSGAQGIVHVVGPEQGLTQPGMTIVCGDSHTSTHGAFGTLGFGIGTSQIRDVLATQCIAMEKQDVRRIQVDGALGEGVYAKDIILKIIGELGVEGGIGYVYEYGGPAIKGLSMEGRMSICNMSVEGGARAGYVNPDLTTFEYMKGRPHAPSGAAWERAVDCWQQIQSDPDATYDDTVTFDGSAIEPMVTWGITPGQALGISEPIPDPARMDSGDRATAEKALDHMDLRPGRTMEGVNVDVAFLGSCTNARITDLREAASLLERLGRPVADDVRAMVVPGSQGVKQQAEDEGLADTFREAGFDWRGAGCSMCLGMNQDQLEGRELCASSSNRNFIGRQGSKDGRTVLMSPAMVVAAAVEGEVTDVRRLMRET
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: NEST_MOUSE
Sequence: MEGCVGEESFQMWELNRRLEAYLTRVKTLEEQNQLLSAELGGLRAQSGDASWRARADDELAALRVLVDQRWREKHEAEVQRDNLAEELESVAGRCQQVRLARERTIEEAACSRRALEAEKNARGWLSTQAAELERELEALRASHEEERAHLNAQAACTPRRPPAPAHASPIRAPEVEELARRLGEVWRGAVRDYQERVAHMESSLGQARERLGQAVRGARESRLEVQQLQADRDSLQERREALEQRLEGRWQDRLQATEKFQLAVEALEQEKQGLQSQIAQILEGGQQLAHLKMSLSLEVATYRTLLEAENSRLQTPGRSSQASLGFPDPKLKLHFLGIPEDQHLGSVLPVLSPTSFSSPLPNTLETPVTAFLKTQEFLKARTPTLASTPIPPMSEAPYPKNAEVRAQDVPHSLLQGGRQQAPEPLWAEATVPSSTGVLPELEEPGGEQPDHFPDDPTSLAPPLNPHHSILEAKDRESSESRVSSIFQEEEGQIWELVKKEAATEVKVENSLAQEIQESGLDTEEIQDSQGPLQMETLEALGDEPLMSLKTQNHETPGKENCNSSIEENSGTVKSPEKEKQTPLKSLEEKNVEAEKTLENGVLELSKPLGEEEPRMEDQELMSPEHTLETVSFLGKENQEVVRSSEEQNLESLITFKEESQYPLGGPEAEDQMLERLVEKEDQRFPRSPEEDQQAFRPLEKENQEPLRFEEAEDQVLERLIEKERQESLKSPEEEDQQAFRLLEKENQEPLRFEDAEDQVLERLIEKERQESLKSPEEEDQQAFRLLEKENQEPLRFEEAEDQVLERLVEKESQESLKSPEEEDQRTGKPLEKENQESLRSLDENQETIVLLESKNQRPLRSLEVEEEEQRIVKPLEKVSQVSLESLEKENVQSPRYLEEDDHMIKSLLEDKTHEILGSLEDRNGENFIPPENETQGSLRPPEEEDQRIVNHLEKESQEFLRSPEAEEEEEQVMVRSLEGENHDPLSSVVKEEQMAESKLENESQDSRKSLEDESQETFGSLEKENLESLRSLAGQDQEEQKLEQETQQPLRAVEDEQMTVNPPEKVDPELPKPLRNDQEVVRSLDKENQESLVSLNEGGMETVKSSETENIESLETVGECLGRRKSVDTQEPLWSTEVTSETIEPLEDETQEPLGCVDENQEVLTPLERESQELRSLGKWNPETVESPGGVEDSQQCLEVEEGPEREQHQESLRSLGEVEWELPGSGSQQRWEDVVEDGEGQEASLGATGVETEDKAELHLRGQGGEEKAVEEGELLQDAVGEAWSLGSSEPKEQRVPAEPLDDLEGQPEQTGTLEVPVAQGMPEATEQDEDRAQAGEQDSVEVTLGLEAARAGLELEQEVVGLEDPRHFAREEAIHPSLGEESVKAKIDQGLEEPGKEPKEAGALDSGIPELPKTSSETLECKGWEESGEGWGEEEASLETSDHEGSHAPQPRPPKTEEDEGLQAALTVPGPKLLEPCSPIPILTDAHELQPQAEGIQEAGWQPEAGTEALGRVEDEPEFGRGEIPEGLQDWEEGREDSEADELGETLPDSTPLGLYLKSPASPKWEQAGEQRLFPQGEARKEGWSPAALAAQGLSDPPEEEQQGHDSDLSSEEFEDLGTEASLLPGVPKEVSDHLGQEPPVLQPACWDQGGESDGFADEEESGEEGEEEDADEEEGAESGTQWWGPGPSGGGVKVQDVTQRGDLEHESVGDSGLWDDGLSGAAANVLVTALETVSQDSAEPSGSEGSESASLEGEEGQAIDHLDAPQEVTSVVPGAGDTFDISGQGPNLESEQVNGRMENGLEQAEGQVVLHGDEDQGIPLQEQGTLKAPLVGSPVHLGPSQPLKFTLSGVDGDSWSSGED
What is the function of this protein?
Required for brain and eye development.  Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division (By similarity).  Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells.
What are the official names of this protein?
Nestin.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: TRIM2_BOVIN
Sequence: MASEATNIPSPVVRQIDKQFLICSICLERYKNPKVLPCLHTFCERCLQNYIPAHSLTLSCPVCRQTSILPEKGVAALQNNFFITNLMDVLQRSPGSSAEESSILETVTAVAAGKPLSCPNHDGNVMDFYCQSCETAMCRECTEGEHAEHPTVPLKDVVEQHKASLQVQLDAANRRLPEIDSALQFISEIIHQLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKVLQSQLDTLLEGQESIKSCSNFTAQALNHGTETEVLLVKKQMSEKLNELADQDFPLHPRENDQLDFIVETEGLKKSIHNLGTILTTNAVASETVATGEGLRQTIIGQPMSVTITTKDKDGELCKTGNAYLTAELSTPDGSVADGEILDNKNGTYEFLYTVQKEGDFTLSLRLYDQHIRGSPFKLKVIRSADVSPTTEGVKRRVKSPGSGHVKQKAVKRPASMYSTGKRKENPIEDDLIFRVGTKGRNKGEFTNLQGVAASTNGKILIADSNNQCVQIFSNDGQFKSRFGIRGRSPGQLQRPTGVAVHPSGDIIIADYDNKWVSIFSSDGKFKTKIGSGKLMGPKGVSVDRNGHIIVVDNKACCVFIFQPNGKIVTRFGSRGNGDRQFAGPHFAAVNSNNEIIVTDFHNHSVKVFNQEGEFMLKFGSNGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDGSGSFLSYINTSADPLYGPQGLALTSDGHVVVADSGNHCFKVYRYLQ
What is the function of this protein?
UBE2D1-dependent E3 ubiquitin-protein ligase that mediates the ubiquitination of NEFL and of phosphorylated BCL2L11.  Plays a neuroprotective function.  May play a role in neuronal rapid ischemic tolerance.  Plays a role in antiviral immunity and limits New World arenavirus infection independently of its ubiquitin ligase activity.
What are the official names of this protein?
Tripartite motif-containing protein 2, E3 ubiquitin-protein ligase TRIM2, RING-type E3 ubiquitin transferase TRIM2.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHO80_YEAST
Sequence: MESTSGERSENIHEDQGIPKVILPADFNKCSRTDLVVLISRMLVSLIAINENSATKKSDDQITLTRYHSKIPPNISIFNYFIRLTKFSSLEHCVLMTSLYYIDLLQTVYPDFTLNSLTAHRFLLTATTVATKGLCDSFSTNAHYAKVGGVRCHELNILENDFLKRVNYRIIPRDHNITLCSIEQKQKKFVIDKNALGSLDLDSYSYVNRPKSGYNVLDKYYRRIVQLVGSFNASPDKSRKVDYVLPPNIDIVSESGSQTTQLKGSSSPNSHSSQKRYSEAKDAHIYNKRSKPD
What is the function of this protein?
Cyclin partner of the cyclin-dependent kinase (CDK) PHO85.  Negatively regulates the expression of phosphate-starvation-responsive genes under phosphate-rich conditions.  The PHO80-PHO85 cyclin-CDK holoenzyme phosphorylates and inactivates the transcription factor PHO4, by preventing its association with the transcription factor PHO2 and the nuclear import receptor PSE1, and by promoting association with the nuclear export receptor MSN5, excluding PHO4 from the nucleus.  PHO80-PHO85 phosphorylates and inactivates protein kinase RIM15 by retaining it in the cytoplasm, antagonizing RIM15-induced entry into stationary phase.  PHO80-PHO85 also phosphorylates and inactivates the calcineurin-responsive transcription factor CRZ1, linking PHO85 to calcium signaling.
What are the official names of this protein?
PHO85 cyclin PHO80, Aminoglycoside antibiotic sensitivity protein 3, Phosphate system cyclin PHO80.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. PHO80 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes predominantly to the cytoplasm under phosphate-rich conditions and concentrates in the nucleus upon phosphate starvation.
Protein: RS3_ROSDO
Sequence: MGNKVNPIGMRLQVNRTWDSRWYADTKDYGDLLLEDLAIRDFIKKECHQAGVARVIIERPHKKCRVTIHTARPGVIIGKKGADIEGLRQKIAKMTASELHLNIVEVRKPELDAALVGESIAQQLERRVSFRRAMKRAVQNAMRMGALGIRVNVAGRLGGAEIARTEWYREGRVPLHTLRADIDYAHVEAATAYGIIGIKTWIFKGEIMEHDPAARDRKAQELQDGPAPRGAGGRR
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: DGTL1_CORDI
Sequence: MFSYSSSDWQRRFDEPEKPSRIIAHHDERGPFAKDRARVLHSAALRRLADKTQVVGPRDGDNPRTRLTHSLEVAQIARGIGTGLGLDADLCEMAGLTHDIGHPPYGHNGEKALAEIAQDCGGFEGNAQTLRILSKLEPKIVDDHDQSYGLNLTRAALDAACKYPRTKTNPDGSVNKKYGCYDEDAHILQWVRQGHEDTSACVEAQAMDFSDDIAYSVHDVEDGIVSGRVHLGVLWDFVELAELAEKGARAFGGTPEALVDAADHLRELPIISAAADFDGSLRGYVDLKAMTSQLVGRYVGAVIEASRAANPTGVFGRSTGQVVVPDQVLAEVTLLKTIAVLYVMDDPTHRQRQDRQRERIYRVYDYLVAGGRGALDPMFRLWWEQAESEAQRQRVIIDNISSMTESRLERVAKQSAELSSFMG
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 2 subfamily.
Protein: ML1P_MANSE
Sequence: MAALHWLLLAALLGCTLAEEQAIFYNCEEASEAVCSVKEVRINPCNPNKKCIFKKGVNASISFDFEPNFASSKLVTTLYGPFDVEFDEMTNVDACQYTKCPTEPGKSQVLDYTLYIGKKLPQGTYTFKWKLWNPEETSQLCCFKTTIKIRK
What is the function of this protein?
Binds to lipopolysaccharide from a variety of Gram-negative bacteria and to lipid A.
What are the official names of this protein?
MD-2-related lipid-recognition protein, MsML-1.
What is the protein family that this protein belongs to?
Belongs to the NPC2 family.
Protein: SUCC_MYCA9
Sequence: MDLFEYQAKELFAKHNVPTTPGRVTTTAEDAKAIAEEIGKPVMIKAQVKVGGRGKAGGVKYAATPDDALTHAQNILGLDIKGHIVKKILVAEASDIAEEYYISFLLDRANRTYLAMCSVEGGVEIEVTAEENPDALAKVPVDAVKGVDLALAREIAEKGKLPAEVLDSAAVTIQKLWEVFVGEDATLVEVNPLVRTPDNQILALDGKVTLDGNADFRQPGHAEFEDKDATDPLELKAKEHDLNYVKLDGQVGIIGNGAGLVMSTLDVVAYAGENHNGVKPANFLDIGGGASAEVMAAGLDVILGDSQVKSVFVNVFGGITACDAVANGIVGALKTLGNTASKPLVVRLDGNKVEEGRAILAEFNHPLVIQAETMDAGADKAAALAAASN
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: AGLB1_PYRHO
Sequence: MVKSKVKKVEKGKEGEEKRSTYVLLKKVLIPILVFGFAIYAFYLRHLTAGKYFPDPDTFYHFEIYKLVLKEGLPRYYPMSDAPFGSLIGEPLGLYLLPAAFYKVVSLFGYNELQAFLLWPPFVGFLGVIAVYLLGRKVLNEWTGLWGAVVLTVSTANFSRTFSGNARGDGPFMALFIFASVAMLYYLKESNKTRKIIYGTLFVLLTVISLGAWNGSPFGLMVLLGFASLQTIILFIFGKLEELKKFVKEFYPAYLAILAFGYALTFPGIVKIGGFIRFAFEVFLGLIFLLVIMLYGGRYLNYSDKKHRFLVVTIIVLLGFGGAYAYVGPKLFRLMGGAYQSTQVYETVQELAKTTIGDVKAYYGVESGNGLIFFLSIPGLLILLTKYLYDLFKKAKSDNETLFALVFYTMSLYLLYLAVRFLFLASYAVALFFGIFIGFSMDVIEKMKENIGIKAALGIVLSLMILVIPFVHAPVLARSARALKNTEIEVTGWEQALKWLRSNTSKYATATSWWDYGYWIESSLLGNRRASADGGHARDRDHILALFLARDGNISEVDFESWELNYFIIYLNDWAKFNAISYLGGAITRKEYNGDENGRGRVTTILLTQAAGNVYVNPYARIVIKVIQQNKTRRIAVNIGQLECSPILSVAFPGNIKIKGSGRCSDGSPFPYVVYLTPSLGVLAYYKVATSNFVKLAFGIPTSSYSEFAEKLFSNFIPVYQYGSVIVYEFRPFAIYKIEDFINGTWREVGKLSPGKHTLRLYISAFGRDIKNATLYVYALNGTKIIKRIKVGEIKYMNHLEEYPIIVNVTLPTAQKYRFILAQKGPVGVLTGPVRVNGKITNPAYIMREGESGRLELKVGVDKEYTADLYLRATFIYLVRKGGKSNEDYDASFEPHMDTFFITKLKEGIKLRPGENEIVVNAEMPKNAISSYKEKLEKEHGDKLIIRGIRVEPVFIVEKEYTMIEVSASAPHHSSE
What is the function of this protein?
Oligosaccharyl transferase (OST) that catalyzes the initial transfer of a defined glycan (ManNAcXyl(2)GlcAMan(2)GalNAc in Pyrococcus) from the lipid carrier dolichol-monophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.
What are the official names of this protein?
Dolichyl-phosphooligosaccharide-protein glycotransferase 1, Archaeal glycosylation protein B, AglB-L, AglB-Long, Oligosaccharyl transferase, OST, OTase.
What is the protein family that this protein belongs to?
Belongs to the STT3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SELA_ECOK1
Sequence: MTTETRSLYSQLPAIDRLLRDSSFLSLRDTYGHTRVVELLRQMLDEAREVIRDSQTLPAWCENWAQEVDARLTKEAQSALRPVINLTGTVLHTNLGRALQAEAAVEAVTKAMRSPVTLEYDLDDAGRGHRDRALAQLLCRITGAEDACIVNNNAAAVLLMLAATASGKEVVVSRGELVEIGGAFRIPDVMRQAGCTLHEVGTTNRTHANDYRQAVNENTALLMKVHTSNYSIQGFTKAIDEAELVALGKELDVPVVTDLGSGSLVDLSQYGLPKEPMPQELIAAGVSLVSFSGDKLLGGPQAGIIVGKKEMIARLQSHPLKRALRADKMTLAALEATLRLYLHPEALSEKLPTLRLLTRSAEVIQIQAQRLQAPLAAHYGAEFAVQVMPCLSQIGSGSLPVDRLPSAALTFTPHDGRGSHLESLAARWRELPVPVIGRIYDGRLWLDLRCLEDEQRFLEMLLK
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAM_ECO8A
Sequence: MSDWNPSLYLHFAAERSRPAVELLARVPLENIKYVADLGCGPGNSTALLHQRWPAARITGIDSSPAMIAEARSALPDCQFVEADIRNWQPEQALDLIFANASLQWLPDHYELFPHLVSLLNPQGVLAVQMPDNWLEPTHVLMREVAWEQNYPDRGREPLAGVHAYYDILSEAGCEVDIWRTTYYHQMPSHQAIIDWVTATGLRPWLQDLTESEQQLFLKRYHQMLEEQYPLQENGQILLAFPRLFIVARRME
What is the function of this protein?
Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
What are the official names of this protein?
Trans-aconitate 2-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Tam family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FREY_AILME
Sequence: MVRTMPGALYPRAGLSLFLLYLVLAAVLLRPQPLRPQRSVPEEFSAPLELSQPLSGLVDDYGVRPKHPWPRGPRPLLSRAQQRKRDGPDMAEYYYNAHL
What is the function of this protein?
Key regulator for male fertility expressed transiently in round spermatids where it recruits IZUMO1 at the endoplasmic reticulum (ER) membrane and coordinates the oolemmal binding multimeric complex (IZUMO1 complex) assembly.  Upon complete assembly of the IZUMO1 complex, its ER retention is released, facilitating IZUMO1 complex export to the acrosome.  Through the interaction with SPPL2C, inhibits its intramembrane protease activity directly accessing the catalytic center of an I-CLiP.
What are the official names of this protein?
Protein Frey, Frey regulator of sperm-oocyte fusion 1, FREY1.
Protein: FENR_CHLP8
Sequence: MLDIHNPTTDHQDIRDLTIIGGGPTGIFAAFQCGMNNISCRIIESMSQLGGQLAALYPEKHIYDVAGFPEVPAIDLVESLWAQAERYNPDVVLGEAVTKYTKLDDGTFETRTNAGNVYRSRAVLIAAGLGAFEPRKLPQLGNIDHLTGSSVYYAVKSVDNFKGKRVVIVGGGDSALDWTVGLLKNAESVTLVHRAKEFQGHGKTAHEVEQAKADGLIDVHLQTEVASIEESNGALTHVHLRSSNGEEWTVEADRLLILIGFKSNLGPLAGWDLELAENALVVDSHMKTSVDGLYAAGDIAHYPGKLKIIQTGLSEATMAVRHSLSYIKPGEKIRNVFSSVKMAKEKKAAEQEKKAE
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: CTNA_DROME
Sequence: MLKPDKMGTLTDFGQIALKWDPKNLEIRTMSVEKTLEPLVLQVTTLVNTKGPSKKKKGKSKRASALVAAVEKATENFIQKGEQIAYENPDITQEMLTAVDEVKKTGDAMSIAAREFSEDPCSSLKRGNMVRAARNLLSAVTRLLILADMVDVHLLLKSLHIVEDDLNKLKNASSQDELMDNMRQFGRNAGELIKQAAKRQQELKDPQLRDDLAAARAMLKKHSTMLLTASKVYVRHPELDLAKVNRDFILKQVCDAVNTISDVAQGKSSQPTDIYSGAGELAAALDDFDEGIVMDPMTYSEKRSRQLLEERLESIISAAALMADADCTRDERRERIVAECNAVRQALQDLLSEYMSNMSQKDNSPGLSRAIDQMCRKTRDLRRQLRKAVVDHVSDSFLETTTPLLDLIEAAKSGNEKKVREKSEIFTKHAEKLVEVANLVCSMSNNEDGVKMVRYAAAQIESLCPQVINAASILTVRPNSKVAQENMTTYRQAWEVQVRILTEAVDDITTIDDFLAVSENHILEDVNKCVMALQVGDARDLRATAGAIQGRSSRVCNVVEAEMDNYEPCIYTKRVLEAVKVLRDQVMMKFDQRVGAAVGALSNNSNKDVDENDFIDASRLVYDGVREIRRAVLMNRSSEDLDTDTEFEPVEDLTLETRSRSSAHTGDQTVDEYPDISGICTAREAMRKMTEEDKQKIAQQVELFRREKLTFDSEVAKWDDTGNDIIFLAKHMCMIMMEMTDFTRGRGPLKTTMDVINAAKKISEAGTKLDKLTREIAEQCPESSTKKDLLAYLQRIALYCHQIQITSKVKADVQNISGELIVSGLDSATSLIQAAKNLMNAVVLTVKYSYVASTKYTRQGTVSSPIVVWKMKAPEKKPLVRPEKPEEVRAKVRKGSQKKVQNPIHALSEFQSPADAV
What is the function of this protein?
Associates with the cytoplasmic domain of a variety of cadherins.  The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties.
What are the official names of this protein?
Catenin alpha.
What is the protein family that this protein belongs to?
Belongs to the vinculin/alpha-catenin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell junction, adherens junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction. Note=Found only at cell-cell boundaries.
Protein: RS11_AGRVS
Sequence: MAKEATRVRRRERKNISSGVAHVNSTFNNTMITITDAQGNAIAWSSAGAKGFKGSRKSTPFAAQIAAEDCAKKAQEHGMKSLEVEVCGPGSGRESALRALQAAGFMITSIRDVTPIPHNGCRPRKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: Y003_CHLMU
Sequence: MKNNSAQKIIDSIKQILSIYKIDFDPSFGAVLTDDNDLDYQMLIEKTQEKIQELDKRSQEILQQTGMTREQMEVFANNPDNFSPEEWRALETIRSSCNEYKKETEELIKEVTQDISHTSGKSPTPKAKSSSPKKSKKKNWIPL
What are the official names of this protein?
Uncharacterized protein TC_0003.
What is the protein family that this protein belongs to?
Belongs to the chlamydial CPn_0742/CT_635/TC_0003 family.
Protein: QUEC_PYRHO
Sequence: MKRGVVLFSGGLDSTACLYWAKRHYDEVIMLTINYGSREESVMNKVAEFFSKELKIPLKIIRVNFLNEFSKLSGSALVEGNVPRVSASELEVIERAKETARSVWVPARNLVLISIAASLLDALGGGDIIVGFNKEEGETFPDNTKEFVERVNKALEYATMNKVRVVAPLIELDKRGIARLLKELGAKYEYSNSCYDPKGFTEDGKPIHCGRCESCVRRHRGLMEGIGEDKTVYLVTPKL
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, Archaeosine biosynthesis protein QueC, PreQ(0) synthase.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: GREA_LACLA
Sequence: MEKTFPMTQEGLDKLKLELENLKLVKRPEVIDRIKVARSYGDLSENSEYEAAKDEQAFIEGRISTVETMIRYAEIVDNAKIAKDEVALGKNVTFVEVGETDEESYQIVGTAEADPFSGKISNESPIARVLIGKKVGDIVNVPLPVGEMTVKIVKVD
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: NADK_MANSM
Sequence: MSQDSVKSLQSTFKTVGVVGRPRNDSTLQMHKNIFHWLCEQGYQVLVENEIGKALNLSENHLASLDQIGQHAQLAIVIGGDGNMLSHARILCKYNTPLIGINRGNLGFLTDIDPKNAYAQLEACLNGEFFVEERFLLEAVVKRHGETVARGNAINELVIHPAKIAHMIDFHVYIDDKFAFSQRSDGLIVATPTGSTAYSLSAGGPILTPQLNAIALVPMFPHTLSSRPLVVDGNSKISVNFAEYNIPQLEISCDSQLALDICCNDVVHIQKSPYKLRLLHLHNYNYYNVLSSKLGWLKKLF
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK1_RHOPB
Sequence: MREHCVTSESVTEGHPDKVCDQISDGILDACVAQDPASRVAVETLVSGNIAVIAGEITTTAQIDAERTARAVIKAIGYDDPALGFDSDSCFILTNLRTQSPDINLGVSRGDELGAGDQGVFYGYACDETANLMPIPIALAHTLSLRLTMMRRDGTLPWLRPDGKVQVTMRYGRDGRPCGLDSVVVSAQHDEAVDRDTLVRGLVEGVIYPELHDWLQPGTRVLINPTGRFVVGGPAGDTGVTGRKLMVDTYGGCAQHGGGAFSGKDATKVDRTAAYMARYAAKNVVAAGLAGRCQLALAYAIGQIDPEMISVETFGTETVDGDRICAAVREVFPWTVSGMIAALELRQPRFRKTAAYGHFGREDQGFQWEKTDRSGELLALCTR
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase 1, AdoMet synthase 1, MAT 1, Methionine adenosyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1428_PYRHO
Sequence: MIEYLILTCLAISVTFNMLGSIALHRFPDVYTRLHGATKCTTFGTIFATFAVVIFALARLNETRNPKYLQMALHSLIALLALLLTNPVGAHAIARASHLSGYLPKRAVVDAYLERRREKDE
What are the official names of this protein?
UPF0091 protein PH1428.
What is the protein family that this protein belongs to?
Belongs to the UPF0091 family.
Protein: MQO_RHOJR
Sequence: MSDQNAVETRTDVVLVGAGIMSATLGAILRQVQPDWSITTFERLDAVAAESSDPWNNAGTGHSALCELNYTPQNADGTVDITKAVNVNEQFQVSRQFWAHGVESGVLTQPKEFINPIPHVSFVHGEANAKYLRARYDALAGHPLFAGMEYIDAPDEFTRRLPLMAKGRDFSDPVALNWTQDGTDVDFGALTKQLLGYVGASGGVVHFGHEVTDLTKQSDGSWVVKVTNRRNGVKKVVRAKFVFVGAGGGALHLLQKSGIEEAKGFGGFPVSGAFLRCTNPELIDQHRAKVYGKAAVGAPPMSVPHLDTRVIGNKPGLLFGPYAGWSPKFLKQGRVTDLPSSVKPDNLLSMLGVGVSELGLVKYLISELAMSEAGRIETLREFVPKALGKDWELITAGQRVQVIRRAKGKGGVLEFGTAVVNAADGTIAGLLGASPGASTAVPAMLDVLQRCFPAQYESWKPKLQEMVPSLGVKLSDDTALFSQVWDWTSKVLQLDTSKVEDASVAV
What are the official names of this protein?
Probable malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.