PharMolix/UniProtQA huggingface dataset:
Protein: VRK1_CAEBR
Sequence: MPPKKAAPKKLHELAPEVRVGLKIDDISKKTYIVGKQFATGGFGRIHTCTEDGKSQQMVMKIEPSTNGPLLTEVVVFNRILKKDMIENYKKAKKIQWIGLPHLIANGYFTYNNEKMRYMIIPKYATSLEAVREANGGSLSAKDSLTVADCVLGALEYLHDSDYAHADVKAANILLEKPNDFSSAVLVDFGLAHRTTNNVDKPDKKRAHNGTCIFTSTDAHRGNNPSFRGDVEILAYNLIMWISGSLPWLSLEASPDKVFEAKQKFVGGLPGTLQSILTNQPAPVAGCITTMFDVSRKTDYTHKVDMAKLRKKVTEAAQSASTGAQKKPKMTPSRDTTATPKRKSQRAPRVESEDEEEEEKKEVEIKPKKKVQRSRKVVEDDDEEEEVIIPKSTRSRKTKEEGTPRSFNLGMTSSTATSDRVAKKIEMKYKRLATNKPSLVPVTVADASSCESQYESNEPGPSSRVVKKRTSEERDANGEVQLKTPALVSPDVKKTKYKSGISSATKASPTELRRVPGVRNFPKGRRSMIIKETSARYQEKRATRNTKPTFDDSSCSSEV
What is the function of this protein?
Serine/threonine kinase that phosphorylates baf-1, thus regulating the association of baf-1 with chromatin and nuclear membrane proteins during nuclear envelope formation.  May act through the egl-17 signaling pathway.  Essential in hermaphrodites for formation of the vulva, uterus, and uterine seam cells and for development and maintenance of the somatic gonad and thus the germ line.  Acts to prevent cep-1 from triggering an inappropriate cell cycle arrest, thereby promoting germ cell proliferation.  Regulates anchor cell polarity and the timing of anchor cell invasion through the basement membranes separating vulval and somatic gonadal cells during the L3 larval stage (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase VRK1, Vaccinia-related kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. VRK subfamily.
What are the subcellular locations of this protein?
Nucleus. Note=Nuclear during interphase, accumulates at the nuclear rim in prophase and localizes to chromatin throughout metaphase, anaphase and telophase.
Protein: RRP7_SCHPO
Sequence: MDKLKEKGFVKLEIYLENKKRLHSIFLKEDTEDVEKKSLYLINVPITTTEKILKRAISQLGGRIVNIYPNISGLLKSGTHLRVKLVEPAEVKQVIKAASKKTTSLPWKFTQHTGLKRYVESYDRQFVNPRVLAESVDSYMKRVTKKEIAEKRRLFAMKNQPDEDGFVTVVRSGRAPVGRPQDAERQLEKKKDTGIHKDFYRFQLREKKKKALLDLAHKFEFDKQRIQQLKEKRQFKPY
What is the function of this protein?
Plays an important role in the synthesis of 18S rRNA but is not required for the 5. 8S and 25S pathway.  Is necessary for the cleavage at site A2 (By similarity).
What are the official names of this protein?
Ribosomal RNA-processing protein 7.
What is the protein family that this protein belongs to?
Belongs to the RRP7 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus.
Protein: YAE1_LODEL
Sequence: MQPSYKDLHCACQSNSQTNQSSVYSMSDDIWEDDDEDEEQEEYDRGDNSNDYNKDGVGSRQQNKQTQSLAMNEIARRHRKQGYVDGLAKHQEENLQKGFDFAYSIGADLGIKVGRLLARACIADGANNDLKDKSGGSGNDLGSLKECMNALNISKVLDLKYFDDHLNLKDGKHGLIEEWQNKSN
What is the function of this protein?
The complex LTO1:YAE1 may function as a target specific adapter that probably recruits apo-RPLI1 to the cytosolic iron-sulfur protein assembly (CIA) complex machinery.  May be required for biogenesis of the large ribosomal subunit and initiation of translation.
What are the official names of this protein?
Protein YAE1.
What is the protein family that this protein belongs to?
Belongs to the YAE1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RS20_SYNFM
Sequence: MANHKSALKRARQNEERRIRNRARKTRMKNVIRSLEEAIASNSRETALERLKMAVSVIDTTASRGVIHKNTASRKVARLSKRVNAL
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: INCD_CHLT2
Sequence: MTKVYAHSIQQERVVDRIALLERCLDLSNSLPTAKRLAAVAVATILAIALLVVAGLLFSGVLCSPVSVVAASLFFGVGAFLLGGALVGGVLTTEAVTRERLHRSQTLMWNNLCCKTAEVEQKISTASANAKSNDKLENSVSKKGAS
What is the function of this protein?
Host inclusion membrane protein probably involved in early modification events of the chlamydial inclusion.
What are the official names of this protein?
Inclusion membrane protein D.
What are the subcellular locations of this protein?
Secreted. Host vacuole, host pathogen-containing vacuole, host pathogen-containing vacuole membrane; Multi-pass membrane protein. Note=Secreted, probably by a type III secretion system (Probable). Localized in the inclusion membrane (PubMed:10447885). Inclusion membrane staining is punctate (PubMed:10447885).
Protein: RUVC_ALIB4
Sequence: MKILGIDPGTRNCGYAIVEKNGRDLKLIEAGLIKIKTKILQEQIVEMTEGLDLLFKNHKIDQVSIEDMFYAFNPKTVIKLAQFRGAISLKILQEFGNFSEYTPLQVKQAVTGNGKATKEQVAFMVKRLLNVKKEIKPLDITDAIAIALTHAQRL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: DAPE_BURP1
Sequence: MSATLALTEQLIARASVTPDDQHCQQLMIERLAALGFECETIASHGVTNFWAVKRGTAGRAGKLLAFAGHTDVVPTGPLEQWRSPPFVPTHRDGKLYGRGAADMKTSLAGFVVAAEEFVAAHPQHRGSIGFLITSDEEGPATDGTVKVVEALAARGERLDYCIVGEPTSTATLGDVVKNGRRGSMSGELVVKGVQGHIAYPHLAKNPIHLLAPALAELAAEQWDEGNEYFPPTTWQVSNLRAGTGATNVIPGHADLLFNFRFSTASTVEGLQARVHAILDRHGLDYTLNWSVSGLPFLTPRGELSNALDAAIRAETGVSPELSTTGGTSDGRFIARICPQVIEFGPPNASIHKIDEHIDVRFVDPLKNVYRRVLEQLIA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: LOLA_PSEE4
Sequence: MRAIRMLLVSALAMGAVSAHADEKDVARLTQLLEKSQTITARFSQLTLDASGTSLQEANGEMAVKRPGLFYWHTDAPQEQVVVSDGQKVTLWDPDLEQATIKKLDVRLSQTPALLLSGDVSKISQSFDISSKEQGEVTDFTLKPKTKDTLFDSLRVSFRKGLINDMQLVDSVGQRTNILFNGVKANEAIPASKFKFDVPKGADVIQE
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MRAZ_STAAM
Sequence: MFMGEYDHQLDTKGRMIIPSKFRYDLNERFIITRGLDKCLFGYTLDEWQQIEEKMKTLPMTKKDARKFMRMFFSGAVEVELDKQGRINIPQNLRKYANLTKECTVIGVSNRIEIWDRETWNDFYEESEESFEDIAEDLIDFDF
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: CCMC_PSEAE
Sequence: MMNWTWFHKLGSPKWFYEISGRWLPWFAVAAALLIVTGCVWGLAFAPPDYQQGNSFRIIYIHVPAAFLAQSCYVMLAVAGAVGLIWKMKIADVAVQCAAPIGAWMTFVALLTGAVWGKPTWGAWWVWDARLTAMLILLFLYFGIIALGQAISNRDSAAKACAVLAIVGVVNIPIIKYSVEWWNTLHQPATFTITEKPAMPVEMWLPLLIMVLGFYCFFAAMLLVRMRLEVLKRESRTAWAKAEVKALVEKAR
What is the function of this protein?
Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.
What are the official names of this protein?
Heme exporter protein C, Cytochrome c-type biogenesis protein CcmC.
What is the protein family that this protein belongs to?
Belongs to the CcmC/CycZ/HelC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS20_RALSO
Sequence: MANTAQARKRARQAVVQNAHNSALRSRLRTAVKAVRKAIAGGDKAAAANVFKQAQSTIDSIADKKIVHKNKAARAKSRLSAAIKAMGA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: GP105_HHV6G
Sequence: MATARLGVMRPPRSCALIFLCAFSMATAPTNATAHRRAGTVKSTPPPEDKGNYTAKYYDKNIYFNIYEGRNSTPRRRTLWEIISKFSTSEMLSLKRVKAFVPVDDNPTTTLEDIADILNYAVCDDNSCGCTIETQARIMFGDIIICVPLSADNKGVRNFKDRIMPKGLSQILSSSLGLHLSLLYGAFGSNYNSLAYMRRLKPLTAMTAIAFCPMTTKLELRQNYKVKETLCELIVSIEILKIRNNGGQTMKTLTSFAIVRKDNDGQDWETCTRFAPVNIEDILRYKRAANDTCCRHRDVQHGRRTLESSNSWTQTQYFEPWQDIVDVYVPINDTHCPNDSYVVFETLQGFEWCSRLNKNETKNYLSSVLGFRNALFETEELMETIAMRLASQILSMVGQQGTTIRDIDPAIVSALWHSLPENLTTTNIKYDIASPTHMAPALCTIFVQTGTSKERFRNAGLLMVNNIFTVQGRYTTQNMFERKEYVYKHLGQALCQDGEILFQNEGQKFCRPLTDNRTIVYTMQDQVQKPLSVTWMDFNLVISDYGRDVINNLTKSAMLARKNGPRYLQMENGPRYLQMETFISDLFRHECYQDNYYVLDKKLQMFYPTTHSNELLFIPRKLRCPHLGRNLRFPHLGRNLRFPHVGIGSY
What are the official names of this protein?
Glycoprotein 105, gp105.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type II membrane protein.
Protein: GLO2_BUCAP
Sequence: MILTSISVLKDNYVWILYNDNCSCIIIDPGVSEDIIKKIEKKNWKLIAILLTHNHIDHVGGVEEIIRRYPNVTVFGPEETKTRNVNKIVKQGDVIKLLKSEIHVFLTPGHTLGHVSYYLKPYIFCGDTLFSGGCGRVFKNKFFDMYQSINFIKSLPKKTILCCSHEYTLSNLNFAMSILPFDKKIKKYYKKIKKHISQNKTSLPVSLETEKKINIFLRTNEKTIKKAMGLKKDTSSFEVFILLRKEKDDF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: RRP42_AERPE
Sequence: MSITPHRLPVAPVIVREAYLSLLRKGWRPGDRDLKTPRNVKIETGIIEKAEGSALVKLGKTQVIAGVKAGVGAPFKDTPNQGVLTVHAEFVPLASPVFEPGPPDENAIELARVVDRSLREVGAVDLESLVIRPGEKVWVLWVDLYIIDHDGNLFDASMLATMAVLLTARLPRYEESETGEIIISKEGEGEELKVKTRVVTVTTAKIDRYIVVDPNIEEEAVSDVRLVTAVDENGRIVGLQKTGMGSLTEADIETMIGYSLEASKVYFKALEEAIKP
What is the function of this protein?
Non-catalytic component of the exosome, which is a complex involved in RNA degradation.  Contributes to the structuring of the Rrp41 active site.
What are the official names of this protein?
Exosome complex component Rrp42.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family. Rrp42 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBA_EULFU
Sequence: VLSPADKTNVKTAWNAVGGQAGEHGAEALERMFLSFPTTKTYFPHFDLSHGSGQVKAHGKKVADALTNAVSHLDDMPGALSALSDLHAHKLRVDPVNFKLLSHCLLVTLASHHPAEFTPAVHASLDKFFAAVSTVLTSKYR
What is the function of this protein?
Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1.  Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.
What are the official names of this protein?
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: SIR5_XENTR
Sequence: MILLPFHTRRLVSHVYCGLKPASKKKGIALEMARPSSNLADFREAFAKAKHIAVITGAGVSAESGVPTFRGAGGYWRKWQAQHLATPEAFARNPSRVWEFYHYRREVMLTKNPNPAHLAIAECETRLRKQGRKLVVITQNIDELHRKAGSRNLFEIHGSLFKTRCTSCGSVKENYKSPICPALAGKGAPEPDVQDAKIPVEQLPRCDENGCNGLLRPNVVWFGETLDSNLLGEVEKELEICDLCVVVGTSSVVYPAAMFAPQVAARGVPVAEFNMENTPATTSFTFHFQGPCGTTLPPAIARHETELIS
What is the function of this protein?
NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins.  Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.
What are the official names of this protein?
NAD-dependent protein deacylase sirtuin-5, mitochondrial, Regulatory protein SIR2 homolog 5.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class III subfamily.
What are the subcellular locations of this protein?
Mitochondrion. Cytoplasm, cytosol. Nucleus. Note=Mainly mitochondrial. Also present extramitochondrially, with a fraction present in the cytosol and very small amounts also detected in the nucleus.
Protein: TM207_HUMAN
Sequence: MSRSRLFSVTSAISTIGILCLPLFQLVLSDLPCEEDEMCVNYNDQHPNGWYIWILLLLVLVAALLCGAVVLCLQCWLRRPRIDSHRRTMAVFAVGDLDSIYGTEAAVSPTVGIHLQTQTPDLYPVPAPCFGPLGSPPPYEEIVKTT
What are the official names of this protein?
Transmembrane protein 207.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: OTC_AKKM8
Sequence: MNNLLSIEQLTGDEIRDLLALGHRLKAERGHHERLPLKGQTWALIFSKSSTRTRVSFEVGISELGGRPMFLSVHDIQLGRGEPIKDTARVLGRMIHGAAIRTYGQQEVEEFASFSGIPTINALTDEEHPCQILADLLTIEEIYGPGSWKDMKIAFVGDGDNNMSRSWMWAAKRLGFTLAIGAPTNYLPLEDFRRHLDCENVIFTTDPVEAVKGASVINTDVWLSMGQESEGLSKEKHFYPYQVNRELLEHAASGHSVFHCLPAYRGKEITEDVLEHFAPVIFREAENRVHAQKAVLATLADARRG
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRAM_AGRFC
Sequence: MESEDATLTKKVELRPLVGLTRGLHPADLEKLTIDAIRAHRRLVEKADELFQALPESYKSGKEVGGPQHLCYIEASIEMHAQMSAVSTLISILGYIPNATVN
What is the function of this protein?
Negatively regulates conjugation and the expression of tra genes by antagonizing TraR/AAI-dependent activation.  TraM may either bind or modify TraR or AAI making them unavailable.  Alternatively, TraM may bind tra promoters preventing TraR activation.
What are the official names of this protein?
Transcriptional repressor TraM.
Protein: SYM_LEPBA
Sequence: MSKHILVTSALPYANGSIHLGHILEAVQTDIWVRFQKLIGNECYFFCADDTHGTPIMIAAKKAGKTPESMIEEVQKEHYKDLTSFGVEYDNYYTTNSEENKKFSESIYLTLKKNGHIVARNIEQSYCEHDKMFLPDRFIKGTCPKCGAKDQYGDSCEVCGTSYSPKDLKDSYCSICGTTPVLRESKHLFFKLQDFQNQLKNWMEEGNRLNEGAQKKLQEWFTSGLQEWDISRDGPYFGFAIPEEENKYFYVWLDAPIGYMASSLNHLKDERKFNEFWKEGKGEIVHFIGKDILYFHGLFWPAMLMGSGYKAPSQLNVHGFLTVNGEKMSKSRGTFINASTFAKYLDVEHFRFYLACRLGSGMEDVDISFDDFVSRVNSDLIGNLVNLVSRVSTSILDKMDRKLGILSTEGKSLVSELLSKETEIREAYVSRNYSKVMRDITGLGDKVNKYVNDYAPWNLIKTDVEKAREVVTTSLNCAKILFTYLAPVTPKIVHSLADLFQIPNLSFLNLTETIENKVLGPYQMLSKRVEEKNITIMITETKETFEKSNPEKAKQDPSKSNTNEVKSATVSEDGFITIDELSKVELRVGLIKEANPVEGADKLLFVKVDLGEKGIKNVFAGIKASYTAEELVGKKVVVVANLKPRQMKFGLSEAMLLASGKDKTLSLFVPDRDASPGDLLK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPC25_DROYA
Sequence: MAIIMAESSYERRVKALYEKQIRMEALEGKFIKKVYKFNSNLLDVKEAVLRHQRKVGKLQKVVMERREELEKRVSFMEELAQELEATKLRNLAMKDQIKQRKMLARQRKNEIMERIHTLSKTTGTYVNHEALPARVKGVTVLRGDKRDQLIPFDLNATDAEGLDSLCQHLESLNVDVSQWQQLVSLAMDVAMEARAPITPPKEAANCKSIIEIDLTSPTSHQA
What is the function of this protein?
Acts as a component of the essential kinetochore-associated Ndc80 complex, which is required for chromosome segregation and spindle checkpoint activity during meiosis and mitosis.  Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.  Participates in SAC signaling that responds specifically to disruptions in spindle microtubule dynamics.  The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules.
What are the official names of this protein?
Kinetochore protein Spc25.
What is the protein family that this protein belongs to?
Belongs to the SPC25 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore.
Protein: RL9_DESDA
Sequence: MKLILRADVENLGSLGDVVDVKPGYGRNFLLPQGLAMVASQANLKVFEQERKKLQAHMDALRAEAQDMQARLEALDVVITMHVGDNDKLYGSVTTTIIGDAIAALGVDVDRRRILMDAPIRTLGEHPVRVRLHPSVIALVPVKVVSDHQSFEEEPAPEAPAEEAEAAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: ISPH_WOLPP
Sequence: MEIILAEPRGFCAGVKRAVDILAITLEKYKNERQVYVLHEIVHNKYIVEGFKKQGVVFVSSIEDIKDNRGILIFSAHGVSKSIEDEAKRKGVQVIDATCPLVSKVHKEAKRYEDSGKELILIGHENHPEVKGIIGRVSNPISLVQTMQDVYNLQIKDPDNLSYVTQTTLSIDDTKEIIATLKLRFPSITGPDLKDICYATQNRQNAVKKLAKITDVVLIVGSKNSSNSNRLLDLCISTGKRAYLIDNYKCMNKNWLQGAEKIGITAGASAPDILVDELVNYLKINMNTKVSVMPDGFTENVQFKYTKW
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: AP3D1_HUMAN
Sequence: MALKMVKGSIDRMFDKNLQDLVRGIRNHKEDEAKYISQCIDEIKQELKQDNIAVKANAVCKLTYLQMLGYDISWAAFNIIEVMSASKFTFKRIGYLAASQSFHEGTDVIMLTTNQIRKDLSSPSQYDTGVALTGLSCFVTPDLARDLANDIMTLMSHTKPYIRKKAVLIMYKVFLKYPESLRPAFPRLKEKLEDPDPGVQSAAVNVICELARRNPKNYLSLAPLFFKLMTSSTNNWVLIKIIKLFGALTPLEPRLGKKLIEPLTNLIHSTSAMSLLYECVNTVIAVLISLSSGMPNHSASIQLCVQKLRILIEDSDQNLKYLGLLAMSKILKTHPKSVQSHKDLILQCLDDKDESIRLRALDLLYGMVSKKNLMEIVKKLMTHVDKAEGTTYRDELLTKIIDICSQSNYQYITNFEWYISILVELTRLEGTRHGHLIAAQMLDVAIRVKAIRKFAVSQMSALLDSAHLLASSTQRNGICEVLYAAAWICGEFSEHLQEPHHTLEAMLRPRVTTLPGHIQAVYVQNVVKLYASILQQKEQAGEAEGAQAVTQLMVDRLPQFVQSADLEVQERASCILQLVKHIQKLQAKDVPVAEEVSALFAGELNPVAPKAQKKVPVPEGLDLDAWINEPLSDSESEDERPRAVFHEEEQRRPKHRPSEADEEELARRREARKQEQANNPFYIKSSPSPQKRYQDTPGVEHIPVVQIDLSVPLKVPGLPMSDQYVKLEEERRHRQKLEKDKRRKKRKEKEKKGKRRHSSLPTESDEDIAPAQQVDIVTEEMPENALPSDEDDKDPNDPYRALDIDLDKPLADSEKLPIQKHRNTETSKSPEKDVPMVEKKSKKPKKKEKKHKEKERDKEKKKEKEKKKSPKPKKKKHRKEKEERTKGKKKSKKQPPGSEEAAGEPVQNGAPEEEQLPPESSYSLLAENSYVKMTCDIRGSLQEDSQVTVAIVLENRSSSILKGMELSVLDSLNARMARPQGSSVHDGVPVPFQLPPGVSNEAQYVFTIQSIVMAQKLKGTLSFIAKNDEGATHEKLDFRLHFSCSSYLITTPCYSDAFAKLLESGDLSMSSIKVDGIRMSFQNLLAKICFHHHFSVVERVDSCASMYSRSIQGHHVCLLVKKGENSVSVDGKCSDSTLLSNLLEEMKATLAKC
What is the function of this protein?
Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated.  The complex is associated with the Golgi region as well as more peripheral structures.  It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes.  Involved in process of CD8+ T-cell and NK cell degranulation (PubMed:26744459).  In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals (By similarity).
What are the official names of this protein?
AP-3 complex subunit delta-1, AP-3 complex subunit delta, Adaptor-related protein complex 3 subunit delta-1, Delta-adaptin.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes large subunit family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MURD_STRPZ
Sequence: MKVISNFQNKKILILGLAKSGEAAAKLLTKLGALVTVNDSKPFDQNPAAQALLEEGIKVICGSHPVELLDEDFEYMVKNPGIPYDNPMVKRALAKEIPILTEVELAYFVSEAPIIGITGSNGKTTTTTMIADVLNAGGQSALLSGNIGYPASKVVQKAIAGDTLVMELSSFQLVGVNAFRPHIAVITNLMPTHLDYHGSFEDYVAAKWMIQAQMTESDYLILNANQEISATLAKTTKATVIPFSTQKVVDGAYLKDGILYFKEQAIIAATDLGVPGSHNIENALATIAVAKLSGIADDIIAQCLSHFGGVKHRLQRVGQIKDITFYNDSKSTNILATQKALSGFDNSRLILIAGGLDRGNEFDDLVPDLLGLKQMIILGESAERMKRAANKAEVSYLEARNVAEATELAFKLAQTGDTILLSPANASWDMYPNFEVRGDEFLATFDCLRGDA
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_DICNV
Sequence: MSTKPKPRYRRILLKMSGEALMGNQAFGLDPKVVNRIADEVRQLHEAGVQVAIVIGGGNLFRGAQLAALGMERVTGDHMGMLATLMNSLAMQDALEQIGVPVRTVSALRVDEICEPYIRRRAIRHLEKGNVVISAAGTGNPFFTTDSAASLRAIELEVDAMFKATKVDGIYTKDPNRYDDAVKYHDLSYQKALTDNLGVMDATSIVMCRDNHMPLIVFDMTKAGEIIRAVFGEDVGTIVHA
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINE_COLP3
Sequence: MALLDYFLRKKEKQVTTASKAKERLQIIVAHERNSRNKQPDYLPQLTEDILKVLRKYIKVSDESFSINLDKKDGDLNVLELNIELHDEQTAD
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: SKIP_ARATH
Sequence: MKSLNDLPAPKSTTTTYYDHSNDAWFKNRVTESETVKSSSIKFKVVPAYLNRQGLRPKNPEDFGDGGAFPEIHLPQYPLLMGKNKSNKPGAKTLPVTVDAQGNVVFDAIVRQNENSRKIVYSQHKDIIPKFLKNEGDLGTVVDEEEELQKEIQETAEETKAAIEKIVNVRLSAAQPSNIARQSGDSQYIKYKPSQQSSAFNSGAKERIIRMVEMPVDPLDPPKFKHKRVPRASGSPPVPVMHSPPRPVTVKDQQDWKIPPCISNWKNPKGYTIPLDKRLAADGRGLQDVQINDNFAKLSEALYVAEQKAREAVSMRSKVQKEMVMKDKERKEQELRALAQKARSERTGAAMSMPVSSDRGRSESVDPRGDYDNYDQDRGREREREEPQETREEREKRIQREKIREERRRERERERRLDAKDAAMGKKSKITRDRDRDISEKVALGMASTGGKGGGEVMYDQRLFNQDKGMDSGFAADDQYNLYDKGLFTAQPTLSTLYKPKKDNDEEMYGNADEQLDKIKNTERFKPDKAFTGASERVGSKRDRPVEFEKEEEQDPFGLEKWVSDLKKGKKPLDKIGSGGTMRASGGGGSSSRDDDHGGSGRTKINFERSDRR
What is the function of this protein?
Splicing factor involved in post-transcriptional regulation of circadian clock and flowering time genes.  Associates with the pre-mRNA of PRR7, PRR9, ELF3 and GI, and is necessary for the regulation of their alternative splicing and mRNA maturation.  Probably involved in splice site recognition.
What are the official names of this protein?
SNW/SKI-interacting protein, AtSKIP, Protein EARLY FLOWERING AND INSENSITIVE TO PHOTOPERIOD 1, SNW domain-containing protein.
What is the protein family that this protein belongs to?
Belongs to the SNW family.
What are the subcellular locations of this protein?
Nucleus speckle.
Protein: SPEH_NITSB
Sequence: MKSLGKHLLAEYYRCDENAINDVQKVEEALVKAAEIAGATVIGKSFHRFEPYGVSGVVVISESHLTIHTWPEYGFAAVDVFTCGDHVDPMKAHEYLKEVFQTQNATVETILRGVLNIPDLRHKPGGSCITGNCGDKKIG
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.