PharMolix/UniProtQA huggingface dataset:
Protein: GLPK_MOUSE
Sequence: MAAAKKAVLGPLVGAVDQGTSSTRFLVFNSKTAELLSHHQVEIKQEFPREGWVEQDPKEILQSVYECIEKTCEKLGQLNIDISNIKAIGVSNQRETTVVWDKVTGEPLYNAVVWLDLRTQSTVENLSKRIPGNNNFVKSKTGLPLSTYFSAVKLRWLLDNVKKVQEAVEENRALFGTIDSWLIWSLTGGIHGGVHCTDVTNASRTMLFNIHSLEWDKELCEFFGIPMEILPNVRSSSEIYGLMKISHSLKAGALEGVPISGCLGDQSAALVGQMCFQDGQAKNTYGTGCFLLCNTGHKCVFSEHGLLTTVAYKLGRDKPVYYALEGSVAIAGAVIRWLRDNLGIIKSSEEIEKLAKEVGTSYGCYFVPAFSGLYAPYWEPSARGIICGLTQFTNKCHIAFAALEAVCFQTREILDAMNRDCGIPLSHLQVDGGMTSNKILMQLQADILYIPVVKPSMPETTALGAAMAAGAAEGVGVWSLEPEDLSAVTMERFEPQINAEESEIRYSTWKKAVMKSIGWVTTQSPESGDPSIFCSLPLGFFIVSSMVMLIGARYISGIP
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.
What are the official names of this protein?
Glycerol kinase, GK, Glycerokinase, ATP:glycerol 3-phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Bound to the mitochondrial surface or cytoplasmic.
Protein: CSST1_CONRO
Sequence: MQTAYWVMVMMMVWITAPLSEGGKPNDVIRGLVPDDLTPQLILRSLISRRRSDKDVREGYKCVWKTCMPALWRRHDLKGKD
What is the function of this protein?
Moderately activates human somatostatin receptors (SSTR) with a specific activation of SSTR1 (EC(50)=2. 9 uM) and SSTR4 (EC(50)=5. 1 uM).  In vivo, does not cause behavioral changes in mice within a few minutes of intracranial injection, but causes a progressive loss of movement thereafter.  Four to five hours after injection, mice recover, even with the highest dose tested (5. 4 mg/kg).  Shows antinociception and antihyperalgesia activities in two mouse models of acute pain, most probably by acting outside the central nervous system.
What are the official names of this protein?
Consomatin Ro1, ConSST Ro1, Somatostatin-related peptide, SSRP.
What is the protein family that this protein belongs to?
Belongs to the conotoxin C superfamily. Consomatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: YL750_MIMIV
Sequence: MELLINNKIKITINLPSKIDWINIPTFLDNYSDDESKITVLKKIVSKNQLTGTIYPTIINVLEMFGSDENKFRVFKIIKNHVLLIADINLLIDLIGLFIDDCFKMKLILEFNHHIYNVKHPFLEFMVKTINSDKNKIHVLSILVPKVLVLDNEDIIRTVHYLSDSFILVDFFKLISPKSKLSFDNVVDIMYTIKSDQQNLKILDVLVSNGFKVCPDQLLEMCRALKSTKSMTKMIGKIPLAKNISDTDKFCEKLAQIIIHPTDYINATDILNINQKISLQYKPHSQGNIIVSGFLTSHVVQKVFCEHEKTTIVYSNSTTMKWTKHSTEYTFINDNDAV
What are the official names of this protein?
Uncharacterized protein L750.
Protein: M2_I86A3
Sequence: MSLLTEVETPTRNGWECKCSGSSDPLVIAASIIGILHLILWILDRLFFKFIYRRLKYGLKGGPSTEGVPESMREEYRQEQQNAVDVDDGHFVNIELE
What is the function of this protein?
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry.  After attaching to the cell surface, the virion enters the cell by endocytosis.  Acidification of the endosome triggers M2 ion channel activity.  The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur.  Also plays a role in viral proteins secretory pathway.  Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation.
What are the official names of this protein?
Matrix protein 2, Proton channel protein M2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses matrix protein M2 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type III membrane protein. Note=Abundantly expressed at the apical plasma membrane in infected polarized epithelial cells, in close proximity to budding and assembled virions. Minor component of virions (only 16-20 molecules/virion).
Protein: RL7A_CHICK
Sequence: MPKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRSILYKRLKVPPAINQFSQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEQKAAGKGDTPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKSKARLGRLVHRKTCTCVAFTQVNPEDKGALAKLVEAVKTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L7a.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S2542_RAT
Sequence: MDNGVQEGSVRLGEDAEAVLAGAVSTKANHRQVLSSLLSGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRLLYFTYLNEGFLSLWRGNSATMVRVIPYAAIQFSAHEEYKRILGHYYGFRGEALPPWPRLLAGALAGTTAASLTYPLDLVRARMAVTPKEMYSNIFHVFIRISREEGLKTLYFGFTPTVLGVIPYAGLSFFTYESLKSLHREYSGRPQPYPFERMVFGACAGLIGQSASYPLDVVRRRMQTAGVTGHQHGSILSTLRSIVREEGAVRGLYKGLSMNWLKGPIAVGISFTTFDLMQILLRQLQS
What is the function of this protein?
Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3',5'-diphosphate.
What are the official names of this protein?
Mitochondrial coenzyme A transporter SLC25A42, Solute carrier family 25 member 42.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: FABH_YERPN
Sequence: MYTKILGTGSYLPVQVRSNADLEKMVDTSDEWIVTRTGIRERRIAGLDETVATMGFQAAEKALEMAGIDKDDIGLIIVATTSSSHAFPSSACQVQRMLGIKDAASFDLAAACAGFTYALSVADQYVKSGAVKHAIVIGSDVLSRALDPEDRGTIILFGDGAGAVVLGASEQPGIMSTHLHADGRYGELLALPYPDRQQDQPAYVTMAGNEVFKVAVTELAHIVDETLQANNLDRTALDWLVPHQANLRIISATAKKLGMGMDKVVITLDRHGNTSAASVPSAFDEAVRDGRIQRGQLVLLEAFGGGFTWGSALVRF
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEXA_BURM9
Sequence: MIKLTARQQQVFDLIRRAIERSGFPPTRAEIAAELGFSSPNAAEEHLRALARKGVIELAAGASRGIRLLGIDDAPHQLTLPHAALMQLSLPLVGRVAAGSPILAQEHISQHYACDPALFSSKPDYLLKVRGLSMRDAGILDGDLLAVQKRTEAKDGQIIVARLGDDVTVKRLKRRPGGVELIAENPDYENIFVKAGSAEFALEGIAVGLIRPGEF
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: KRA54_HUMAN
Sequence: MGCCGCSGGCGSGCGGCGSGCGGCGSGCGGCGSGCGGCGSGCGGCGSSCCVPICCCKPVCCCVPACSCSSCGSCGGSKGGYGSCGGSKGGCVSCGGSKGGCGSCGGSKGGCGSCGGSKGGCGSCGGSKGGCVSCGGSKGGCGSCGGSKGGCVSCGGSKGGCGSCGGSKGGCGSCGGSKGGCGSCGGSKGGCGSCGCSQCSCCKPCCCSSGCGSSCCQSSCCKPCCSSSGCGSSCCQSSCCKPYCCQSSCCKPCCSSSGCGSSCCQSSCCNPCCSQSSCCVPVCCQCKI
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Keratin-associated protein 5-4, Keratin-associated protein 5.4, Ultrahigh sulfur keratin-associated protein 5.4.
What is the protein family that this protein belongs to?
Belongs to the KRTAP type 5 family.
Protein: RS2_CHRSD
Sequence: MAQVNMRDLLKAGAHFGHQTRYWNPKMSKYIFGARNKIHIINLEHTLPALNDALAVIEKMVASNNKILFVGTKRAASKIVKEEARRAGQPFVNHRWLGGMLTNFKTIRVSIKRLRELEAMHEDGTFEKLTKKEVLMATREQDKLERSVGGIKDMGGLPDALFVVDVDHERIAINEANKLGIPVIGVVDTNSNPDGVDYVIPGNDDSIRAIQIYAQAVADVCVRAKDNSASEFVEVTETNENEAAAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: CLE13_MEDTR
Sequence: MGRYTTDQVQVYVLVIVLCTFFSTLQARSLRDHPLIHKNIDSRSLLQKLRIHISNHKQVRDISGDRLSPAGPDPQHNGRSPPRK
What is the function of this protein?
Signaling peptide involved in the regulation of nodulation (PubMed:20348212).  Moves from root to shoot to function with the receptor kinase SUNN, in a signaling pathway that plays roles during cellular differentiation, both at the onset of nodulation, and later during nodule meristem development and subsequent homeostasis (PubMed:20348212).  Interacts with SUNN signaling to control nodule numbers (PubMed:22168914).  SUNN is involved in the autoregulation of nodulation (AON), a long distance systemic signaling from root to shoot and back again, which allows legumes to limit the number of root nodules formed based on available nitrogen and previous rhizobial colonization (Probable).
What are the official names of this protein?
CLAVATA3/ESR (CLE)-related protein 13, MtCLE13.
What is the protein family that this protein belongs to?
Belongs to the CLV3/ESR signal peptide family.
What are the subcellular locations of this protein?
[CLE13p]: Secreted, extracellular space.
Protein: SRY_NEOSC
Sequence: MFGVLNSSDHRAAVQQRNIPAFGRTSFELWTDNPTSNYRCETGGNGRDSGQNRVRRPMNAFMVWSRDQRRRVALENPQMKNSEISKQLGYQWKMLTEAEKWPFFEEAQRLQAMHREKYPDYKYRPRPKALPQKSDKLLPAASSSMLCRQVLVDEKWYPFTYRDSCSRAAHPRMEDQLSSSQPVNIANSLLQQEHHYCSTSLRDSPETLAMHLSADPPFYPK
What is the function of this protein?
Transcriptional regulator that controls a genetic switch in male development.  It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells.  Involved in different aspects of gene regulation including promoter activation or repression.  Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.  SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending.  Also involved in pre-mRNA splicing (By similarity).  In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity).
What are the official names of this protein?
Sex-determining region Y protein, Testis-determining factor.
What is the protein family that this protein belongs to?
Belongs to the SRY family.
What are the subcellular locations of this protein?
Nucleus speckle. Cytoplasm. Nucleus.
Protein: TILS_XANAC
Sequence: MRCEVAPVLTGTPLLPATPPGPVLLAYSGGMDSSVLLHLLAARPRYRHAGLRALHVHHGLHADADAWAAHCQRTCDALQVPLQIVRVQVARDSGLGLEAAARNARHAAFAQALIAGEWLALAHHRDDQAETFLLRALRASGPEGLAAMRPQRPFASGTLWRPMLAHARADLLAYAHAHRLRWIDDPSNTDPRHDRNFLRSQVLPLLQQRWPQATDALARSAQLSADASALLLQQDMALLPGVLTASGALDLQALRAQSVERRARLLRAWVSAAHAPPLPAHGVAALEQEIDNHAADRHACFAWQQVEVRRWRQCLFLHRPAAAWPSDWHAQWDGAAPLQLPDGAQLRLLGAPGLRFAQPLLVRARQGGERIVLPQRGHSHQLKHLLQALDLPPWERERLPVLWEGAQVLAAGDCIISGTLDAWLQANAAALQWRTAADAN
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_STAAR
Sequence: MIKIPRGTQDILPEDSKKWRYIENQLDELMTFYNYKEIRTPIFESTDLFARGVGDSTDVVQKEMYTFKDKGDRSITLRPEGTAAVVRSYIEHKMQGNPNQPIKLYYNGPMFRYERKQKGRYRQFNQFGVEAIGAENPSVDAEVLAMVMHIYQSFGLKHLKLVINSVGDMASRKEYNEALVKHFEPVIHEFCSDCQSRLHTNPMRILDCKVDRDKEAIKTAPRITDFLNEESKAYYEQVKAYLDDLGIPYIEDPNLVRGLDYYTHTAFELMMDNPNYDGAITTLCGGGRYNGLLELLDGPSETGIGFALSIERLLLALEEEGIELDIEENLDLFIVTMGDQADRYAVKLLNHLRHNGIKADKDYLQRKIKGQMKQADRLGAKFTIVIGDQELENNKIDVKNMTTGESETIELDALVEYFKK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CEP89_DANRE
Sequence: MSSKFNFSLRRKEKREFRNIAHGLIPAATIAPRPAVPRTPPPRSPNPSPERPRSALAAAILSSSLTGRTVAIPSPRQRSYSESDCSRADSQADFEPYATALYTRDRWPGSVTGRPPVPSPGRTDEDDDEDDEGNDIDELEGLEGDEDHVYQSLERQSRADDINVVYAVPLKHKKSEIDSDVDEETEDSAFDIVSPLQTEEETVVPEGAGQTQPSSLPQPRSVSRRSMASPELDDWSSPRSLKTSKRKSSRTNKESPVRVNERDRSSEDSEVLRSTLEVQHALVKELKEQNQILSQEKETLEKRCLQQSQHMKHLQQELCHTHRERGNSTGEGSELSSLRQQAQELVDENDGLKMTVHRLNVELSRYQARFRPLTKDENAQLKGLPVKGPAPPWLLDMKYLSPLLLAYEDHLNAKDKLLKSCEEELQSLRVRAEEVIQENEKLHTQVSKSSTVSNKEWRQLQEQARLVLEENQVLIEQLELQHAKAKEAHSKHAQEVCKVSKKVMLLEAEKQSLEKELEVERKEHRALKTEFQRVRLALEHSLSLAEHQTVTDKLKRQLQDHEKVKTCEVEDLQVRLSALEVERKTLLLDKTNLNTHIKHLETELQLSQQANRKAQRRVSVLKQQVEDSLEKELIAHQYLANIVTLAEKTTHERDQLMLMASTLEKDKQGVLTRIIESTVNLGKLQEKVKVFLLQS
What is the function of this protein?
Required for ciliogenesis.  Also plays a role in mitochondrial metabolism where it may modulate complex IV activity (By similarity).
What are the official names of this protein?
Centrosomal protein of 89 kDa, Cep89, Coiled-coil domain-containing protein 123.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Mitochondrion intermembrane space. Note=Localizes to the distal appendage region of the centriole, which anchors the mother centriole to the plasma membrane.
Protein: SURE_THESQ
Sequence: MRILVTNDDGIQSKGIIVLAELLSEEHEVFVVAPDKERSATGHSITIHVPLWMKKVFISERVVAYSTTGTPADCVKLAYNVIMDKRVDLIVSGVNRGPNMGMDILYSGTVSGAMEGAMMNIPSIAISSANYESPDFEGAARFLIDFLKEFDFSLLDPFTMLNINVPAGEIKGWRFTRQSRRRWNDYFEERVSPFGEKYYWMMGEVIEDDDRDDVDYKAVREGYVSITPIHPFLTNETCLKKLREVYD
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLIG_MALRE
Sequence: MKSLQTICLLFIFIARGTSDKCEICHGFGDDCDGYQEECPSPEDRCGKILIDIALAPVSFRATHKNCFSSSICKLGRVDIHVWDGVYIRGRTNCCDNDQCEDQPLPGLPLSLQNGLYCPGAFGIFTEDSTEHEVKCRGTETMCLDLVGYRQESYAGNITYNIKGCVSSCPLVTLSERGHEGRKNDLKKVECREALKPASSD
What is the function of this protein?
Inhibits the enzymatic activity of phospholipase A2 (PA2) (PubMed:10924158).  Binds to the major PLA2 toxin of D. russelli siamensis (Daboiatoxin, AC Q7T2R1, and AC Q7T3T5) at 1-2-fold molar excess of inhibitor to toxin (PubMed:10924158).  It exhibits broad spectra in neutralizing the toxicity of various snake venoms and toxins and inhibits the formation of edema in mice (PubMed:10924158).  May bind to PLA2 through its proline-rich hydrophobic core region (Probable).
What are the official names of this protein?
Phospholipase A2 inhibitor PIP, Phospholipase inhibitor from python, PIP, gamma-PLI.
What is the protein family that this protein belongs to?
Belongs to the CNF-like-inhibitor family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted in blood plasma.
Protein: NAC_METM5
Sequence: MFPGGGKFNPRMMKQMQKMMKDFGMDAEDLKAVKVTIELEDTILVFEKPKVQVMDMLGNKTYSITGKAKKVAKAEEKIEDVEVKVEVTEEDIEMVSSQCGVSKEEAKKALEEANGDLAEAILKLGN
What is the function of this protein?
Contacts the emerging nascent chain on the ribosome.
What are the official names of this protein?
Nascent polypeptide-associated complex protein.
What is the protein family that this protein belongs to?
Belongs to the NAC-alpha family.
Protein: UVRB_ECOLI
Sequence: MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLHLTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQIVSTIPRFTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLENNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGEPPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYELEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDIDTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPSMAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVPMDMSPKALQQKIHELEGLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RT14_VICFA
Sequence: MSEKRNIRDHKRRLLAAKYELRRKLYKAFCKDSDLPSDMRDKLRYKLSKLPRNSSFARVRNRCISTGRPRSVYELFRISRIVFRSLASRGPLMGIKKSSW
What are the official names of this protein?
Ribosomal protein S14, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RIBL_METST
Sequence: MASGTFDIIHPGHGFYLSESKKLGGDNAILMVVVATDKTVKNHKRVPIVGEKQRCEMVSMLKGVDEAYVGDEKDPFKIVKEKKPDIITIGPDQNFNPDSLHKSLLKKGLDIKVVKINDYKKFELDSSCKIIRKIKQTDFDMDYLENCQ
What is the function of this protein?
Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
What are the official names of this protein?
FAD synthase, FMN adenylyltransferase, Flavin adenine dinucleotide synthase.
What is the protein family that this protein belongs to?
Belongs to the archaeal FAD synthase family.
Protein: F16P1_BRANA
Sequence: MAATAGATPSSHLLLSSSRHVAASPQPRILFPSLSGKRVAVGKNHHATGVRCMAVAADATAETKPAAKKKSGYELQTLTSWLLRQEMKGEIDTELTIVMSSIAMACKQIASLVQRAGISNLTGVQGAVNIQGEDQKKLDVVSNEVFSNCLRSSGRTGIIASEEEDVPVAVEESYSGNYVVVFDPLDGSSNIDAAVSTGSIFGIYSPNDECLPDSDDTSALGSEEERCIVNVCQPGNNLLAAGYCMYSSSVIFVLTLGKGVFAFTLDPMYGEFVLTQENIEIPKAGKIYSFNEGNYQMWDENLKKYIDDLKDPGPSGKPYSARYIGSLVGDFHRTLLYGGIYGYPRDAKSKNGKLRLLYECAPMSFIVEQAGGKGSDGHHRVLDIQPTEIHQRVPLYIGSKEEVEKLEKYLA
What are the official names of this protein?
Fructose-1,6-bisphosphatase, chloroplastic, FBPase, D-fructose-1,6-bisphosphate 1-phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: GLND_RHILO
Sequence: MAKISLKLDELIDGEALRREMTALTTATAGDGSGAAARAGVLQLLKARLAEGRKIAEAMLKEDGGGNACAERLSHLMDELIRALYDFAATHVYRVKNRSSAERMAVVAVGGYGRGTLAPGSDIDLLFLLPYKQTPWGEQTVEYMLYMLWDLGLKVGHATRNIDECLRLSRTDITIRTSILEARFLWGERKLYDELMLRFDHEVVRTTGPEYVQAKLAERDERHAKAGESRYLVEPNVKDGKGGLRDLQTLFWIGKYFYRVRTGEELVEKGVFTEAEYREFQKAEDFLWAVRCHMHFLTGKAEERLHFDIQREIAERLGYTTHPGLSAVERFMKHYFLVAKDVGDLTRIFCAALEEEQAKHVPGFNRIFLTFQRRKRKLAGTSDFIVDNHRINIADDQVFERDPVNLLRLFWFADKHGLEFHPDALKLLTRSLGLVNKSLRRDEEANRLFLDILTSDRNAELNLRRMNEAGLLGRLIPDFGKIVAMMQFSMYHHYTVDEHLIRCIGVLAEIERGDGEKVHPLSHSLMPGLKKSREALYVAVLLHDIAKGRPEDHSEAGARIARRICPHMGLSAADTETVAWLVENHLAMSMTAQTRDLNDRKTIEDFASIVQSVERLKLLLVLTVCDIRGVGPGVWNGWKGQLLRTLYYETELLLTGGFSEVSRAQRTAAARERLAEALADWPDKDRKRYVGLHYENYLLTVDLPDQLRHAEFVREADAAGKKLATMVKTHQFEAVTEITVLAQDHPRLLSVIAGACVGAGGNIVDAQIFTTADGRALDTILISREFDRDEDERRRAERVGRLIEDVLSGKSWLPEMIEKRTKPKRGAKVFKIPPRAEIRNTLSNRFSVIEVEGLDRPGLLSEITGTLSDLSLDIASAHITTFGEKVIDTFYVTDLTGQKIDSPARIATIRNRLMATLEGIAPERGGKAKAAAE
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: SYC_ROSDO
Sequence: MTIKLYNTKTRRKEDFEPINKDDVRMYVCGPTVYDRAHLGNARPVIVFDVLYRLLRHTYGPDHVTYVRNFTDVDDKINARAAESGRSIAEITAETTQWFLDDMAAVGALEPSIKDRDHQRAMPRATQYIAQMVTMIEDLIAKGHAYAAEGHVLFAVESYSKYGALSGRSIDDMIAGARVEVAPYKRNPMDFVLWKPSDDATPGWAGPVVGGKSIGRGRPGWHIECSAMAHDLLGATFDIHGGGNDLMFPHHENEIAQSTCAGHNFANVWMHNEMLQVEGKKMSKSLGNFFTVRDLLDQGVPGEVIRFVMLSTHYRKPMDWTEKKREEAEETLWKWKKLTDGAESSRRPHLEIIAALKDDLNTPLAISILHRKFAEAKSDDDKNRFLSTLLLLGIGETWRDGVDVAVEEAFQTVSLIEALIESIEKARAQKDWATSDRTRDGLESAGVKVQISKDGVSWERGPSFDPAKLEALK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HMGD_EUBBA
Sequence: MEKSIKIGFIGLGAMGKPMAINLLKEGVTVYAFDLMEANVAAVVAQGAQACENNQKVAAASDIIFTSLPNAGIVETVMNGPGGVLSACKAGTVIVDMSSVSPSSTLKMAKVAAEKGIDYVDAPVSGGTKGAEAGTLTIMVGASEAVFEKIQPVLSVIGKDIYHVGDTGAGDAVKIVNNLLLGCNMASLAEALVLGVKCGLKPETMQEIIGKSSGRSYAMEAKMEKFIMSGDFAGGFAMDLQHKDLGLALEAGKEGNVPLPMTAMATQIFEGGRAMGLGREDMSAVIKVWEQMTGVSVSGGQ
What is the function of this protein?
Catalyzes the conversion of 2-formylglutarate to (S)-2-hydroxymethylglutarate.  Has very low activity with (S)-3-hydroxyisobutyrate.
What are the official names of this protein?
2-(hydroxymethyl)glutarate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the HIBADH-related family.