PharMolix/UniProtQA huggingface dataset:
Protein: ZHD6_ORYSI
Sequence: MEFRGHDEPVDEMGVAYGRTPPSSSSSPAASASAGNGAGAAEVRYHECLRNHAAAMGGHVVDGCGEFMPMPGDAADALKCAACGCHRSFHRKDDGQQQQQLRLLIPSPPTPRVPLLMPPPQPQPHPHPHPQHPYLHPPFPYHHTPSGSGGTTTESSSEERGPPSSSAAAAQGRRKRFRTKFTPEQKEQMLAFAERVGWRMQKQDEALVEQFCAQVGVRRQVFKVWMHNNKSSIGSSSGGGSRRQPQEQQSQQQQQQQ
What is the function of this protein?
Putative transcription factor.
What are the official names of this protein?
Zinc-finger homeodomain protein 6.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL12_PYRAB
Sequence: MEYVYAALLLHSVGKEINEDNLKAVLQAAGVEPDEARIKALVAALEGVNIDEVIEKAAMPVAVAAAPAAAPAEAPAEEKKEEEKKEEEKEEEVSEEEALAGLSALFG
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L12.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein P1/P2 family.
Protein: MED28_XENTR
Sequence: MFSAQQPGPPPPNQPGAPAGLMSTPPGAKNPSSTLVDDLESSFEACFASLVSQDYVNGTDQEEIRTGVEQCIQKFLDVARQTECFFLQKRLQLSVQKPEQVIKEDVSELRNELQRKEALIQKHLTKLRSWQQVLEEINGQHKKTSEMPQGPLAYLEQASANIPAPMKPT
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 28, Mediator complex subunit 28.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 28 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MESH1_HUMAN
Sequence: MGSEAAQLLEAADFAARKHRQQRRKDPEGTPYINHPIGVARILTHEAGITDIVVLQAALLHDTVEDTDTTLDEVELHFGAQVRRLVEEVTDDKTLPKLERKRLQVEQAPHSSPGAKLVKLADKLYNLRDLNRCTPEGWSEHRVQEYFEWAAQVVKGLQGTNRQLEEALKHLFKQRGLTI
What is the function of this protein?
ppGpp hydrolyzing enzyme involved in starvation response.
What are the official names of this protein?
Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1, HD domain-containing protein 3, Metazoan SpoT homolog 1, MESH1, Penta-phosphate guanosine-3'-pyrophosphohydrolase, (ppGpp)ase.
What is the protein family that this protein belongs to?
Belongs to the MESH1 family.
Protein: RS16_ACIBS
Sequence: MVVIRLARGGAKKRPFYQIVVTDSRNARDGRFIERIGFFNPTAQGQAEKLRLDADRFAHWVSQGAQPSERVASLAAQAKKATA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: ACKA_VIBC1
Sequence: MSKLVLVLNCGSSSLKFAVVDAETGAEHLTGLAECLGLPEARMKWKLDGKHEAQLGAGAAHVEALSFMVETILASKPELKANLGAIGHRIVHGGEQFTQSALITDDVLKGIQDAATFAPLHNPAHLIGIEAAKVNFPGLQNVAVFDTAFHQTMPEESYLYALPYNLYKEHGIRRYGMHGTSHLFITREVANLLDKPVEEVNIINCHLGNGASVCAIKNGKSVDTSMGLTPLEGLVMGTRCGDIDPAIVFHLHDALGYSVEQINNMLTKESGLAGLTEVTSDCRFVEDNYGEKEEATRAMDVFCHRLAKYVAGYTASMEGRLDAITFTGGIGENSGPIREMVLNRLGIFGIEVDGEANLKARFGGEGTITTANSRIPAMVISTNEELVIAEDAARLAGL
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_SALAR
Sequence: MTAIAPVITIDGPSGAGKGTLCKAMAEALQWHLLDSGAIYRVLALAALHHHVGLASEDALVPLASHLDVRFVSTDGNLEVILEGEDVSGEIRTQEVANAASQVAAFPRVREALLRRQRAFREAPGLIADGRDMGTVVFPDAPVKIFLDASSEERANRRMLQLQEKGFSVNFERLLAEIKERDDRDRNRAVAPLVPAADALVLDSTRLSIEQVIEKALQYARQKLALA
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVC_NOSP7
Sequence: MEKRILGLDPGLATLGFGVITCTQIANKVPETTVNMLDFGVIKTSADVEMGLRLCTLFDDLHTVMEEFQPDLVAIEKLFFYRMSSTILVAQARGVLILVLGQRRLPYVEFTPAQIKQALTGYGNADKLDVQEAVARELDLDEIPKPDDAADALAVALTASYQL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: MUTS_FLAJ1
Sequence: MAAKEKVAKETPLMKQYNEIKRKYPDACLLFRVGDFYETFGEDAIRASKILGITLTKRGAGSDTETALAGFPHHSINTYLPKLVKAGLRVAICDQLEDPKMTKTIVKRGVTELVTPGVSLNDEVLQSKTNNFLASVCFANKNIGISFLDVSTGEFLTAQGNAEYIDKLLQNFNPSEVLVPKNCKSEFKDAFGEDFHSFYLEDWIYKEDYALETLTKHFQTNSLKGFGVEELKEGIISAGAILYYLSETQHNRVQHITAIQRIAEDAYVWMDRFTIRNLELYHSYNPNAVTLLDVIDKTLSPMGGRLLKRWLALPLKDTNKIKGRHAVVSYLKSNPEILHNIQYQIKQISDLERLISKIAAGKVSPREIVYLKESLDAIIPIKTLALESPQEAVKVIGDSLHSCDLLREKIKTTLNQDAPVAISKGNAIATGVNEELDELRAISTSGKEFLEGIERRESERTGISSLKISFNNVFGYYIEVRNTHKDKVPEEWIRKQTLVNAERYITEELKEYETKILGAEEKIHKIESELFEQLVNWIATYIKPVQMNAYLVAQLDCLCSFTQMAVENQYVCPEIDDTFELDIKNGRHPVIEKQLPVGTPYIANDVFLDREKQQIIMITGPNMSGKSAILRQTALIVLLAQMGSFVPADSVRMGIVDKIFTRVGASDNISMGESTFMVEMNETASILNNISDRSLVLLDEIGRGTSTYDGISIAWAIAEFLHEHPSKAKTLFATHYHELNEMTESLPRIQNYNVAVKELKDTVLFVRKLVKGGSAHSFGIHVAKMAGMPQLVISKAQKLLKKLEKNHSSDALNGIKSANDEMQMSFFNLDDPLLEEIKEEILSLDINAITPVEALMKLNEIKRMLVKK
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: BGL12_ORYSJ
Sequence: MAAAGAMPGGLLLTFLLLAVVASGAYNGAGEPPVSRRSFPKGFIFGTASSSYQYEGGAAEGGRGPSIWDTFTHQHPEKIADRSNGDVASDSYHLYKEDVRLMKDMGMDAYRFSISWTRILPNGSLRGGVNKEGIKYYNNLINELLSKGVQPFITLFHWDSPQALEDKYNGFLSPNIINDFKDYAEICFKEFGDRVKNWITFNEPWTFCSNGYATGLFAPGRCSPWEKGNCSVGDSGREPYTACHHQLLAHAETVRLYKAKYQALQKGKIGITLVSHWFVPFSRSKSNDDAAKRAIDFMFGWFMDPLIRGDYPLSMRGLVGNRLPQFTKEQSKLVKGAFDFIGLNYYTANYADNLPPSNGLNNSYTTDSRANLTGVRNGIPIGPQAASPWLYVYPQGFRDLLLYVKENYGNPTVYITENGVDEFNNKTLPLQEALKDDARIEYYHKHLLSLLSAIRDGANVKGYFAWSLLDNFEWSNGYTVRFGINFVDYNDGRKRYPKNSAHWFKKFLLK
What is the function of this protein?
Hydrolyzes p-nitrophenyl beta-D-glucoside, p-nitrophenyl beta-D-galactoside, p-nitrophenyl beta-D-xyloside, p-nitrophenyl beta-D-fucoside, p-nitrophenyl beta-L-arabinoside, cello-oligosaccharides and laminaribiose.
What are the official names of this protein?
Beta-glucosidase 12, Os4bglu12.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: INAR1_MOUSE
Sequence: MLAVVGAAALVLVAGAPWVLPSAAGGENLKPPENIDVYIIDDNYTLKWSSHGESMGSVTFSAEYRTKDEAKWLKVPECQHTTTTKCEFSLLDTNVYIKTQFRVRAEEGNSTSSWNEVDPFIPFYTAHMSPPEVRLEAEDKAILVHISPPGQDGNMWALEKPSFSYTIRIWQKSSSDKKTINSTYYVEKIPELLPETTYCLEVKAIHPSLKKHSNYSTVQCISTTVANKMPVPGNLQVDAQGKSYVLKWDYIASADVLFRAQWLPGYSKSSSGSRSDKWKPIPTCANVQTTHCVFSQDTVYTGTFFLHVQASEGNHTSFWSEEKFIDSQKHILPPPPVITVTAMSDTLLVYVNCQDSTCDGLNYEIIFWENTSNTKISMEKDGPEFTLKNLQPLTVYCVQARVLFRALLNKTSNFSEKLCEKTRPGSFSTIWIITGLGVVFFSVMVLYALRSVWKYLCHVCFPPLKPPRSIDEFFSEPPSKNLVLLTAEEHTERCFIIENTDTVAVEVKHAPEEDLRKYSSQTSQDSGNYSNEEEESVGTESGQAVLSKAPCGGPCSVPSPPGTLEDGTCFLGNEKYLQSPALRTEPALLC
What is the function of this protein?
Together with IFNAR2, forms the heterodimeric receptor for type I interferons (including interferons alpha, beta, epsilon, omega and kappa) (PubMed:14532120, PubMed:1533935, PubMed:24075985).  Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves (By similarity).  STAT proteins are then phosphorylated by the JAKs, promoting their translocation into the nucleus to regulate expression of interferon-regulated genes (By similarity).  Can also act independently of IFNAR2: form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (PubMed:23872679).
What are the official names of this protein?
Interferon alpha/beta receptor 1, IFN-R-1, IFN-alpha/beta receptor 1, Type I interferon receptor 1.
What is the protein family that this protein belongs to?
Belongs to the type II cytokine receptor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Late endosome. Lysosome. Note=Interferon binding triggers internalization of the receptor from the cell membrane into endosomes and then into lysosomes.
Protein: FABH2_VIBVY
Sequence: MTNYYAEITGWGKCLPPAVLSNDDLSTFLDTSDEWIRTRTGIENRRISHVNTSDLATVAAKQALARAGITAQDIDLIIVATCSPDSLIPNIASMVQKNLEIEAAAAFDLNAACTGFVYGLETGTRLIQSGAYRHALIIGAERLSFYIDWAMRDTAVLFGDGAGAVVLSRTEEAVGLQNAKIGCDAQGRDILSVPKFGTSMDRFAADNGYWDFNFVGKEIFKRAVKGMGSAAAHVLAHAGMSKDDINVVIPHQANIRIIQTLCDLSGIDQSKAFVNIQKYGNTSAATVPIALCEAVEQGHIKAGDNILLAAFGAGLTWGAGLVKWGQRVEAISESDAALPECDKSALELLKNAIELCNARRDK
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III 2, Beta-ketoacyl-ACP synthase III 2, KAS III 2, 3-oxoacyl-[acyl-carrier-protein] synthase 3 2, 3-oxoacyl-[acyl-carrier-protein] synthase III 2.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAS2_MYCTU
Sequence: MPTRSREEYFNLPLKVDESSGTIGKMFVLVIYDISDNRRRASLAKILAGFGYRVQESAFEAMLTKGQLAKLVARIDRFAIDCDNIRIYKIRGVAAVTFYGRGRLVSAEEFVFF
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  The type III-A Csm effector complex binds crRNA and acts as a crRNA-guided RNase, DNase and cyclic oligoadenylate synthase; binding of target RNA cognate to the crRNA is required for all activities (Probable).  This CRISPR-Cas system protects bacteria against transformation with plasmids containing DNA homologous to its spacer regions (PubMed:29979631).
What are the official names of this protein?
CRISPR-associated endoribonuclease Cas2.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Protein: EFPL_XANAC
Sequence: MKANDIKKGNVVEYNGGIYQIRDIERSSPQGRGGNVRFRFIMYSVPGGVKTDASFDADDNLPEVELLRRQSTFSYKDGEAFVFMDDEDFTPYTLDADVIGTDAGYITDGLTGIYVQVIDEQPVAVQLPQTVTLEVVETPPELKGGTATKRPKPAKLNTGMEIMVPEYITNGERVLVNTTTGEFAGRAD
What are the official names of this protein?
Elongation factor P-like protein.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
Protein: Y2443_LISMC
Sequence: MASKQLKLVIITGMSGAGKTVAMQSLEDLGYFCVDNLPPSLLPKFWELMKESDKMDKIALVMDLRGREFFDSIEPALDELDNTNFITTKILFLEADDKVLVSRYKETRRHHPLEPNGSVLDGINAERELLSDLKGRSQLVINTSNMAPRELRERINNEFQTEDKDIFNVQLMSFGFKYGIPIDADLVFDVRFLPNPHYIDKMRPLTGLDEDVYEYVMKWPETQTFLDKLVDLLMFTLPFYKREGKTQLVIAIGCTGGQHRSVALTEFVGKAIQQKYETTISHRDMKRRKGR
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Lm4b_02443.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: RLMH_LEUCK
Sequence: MNIKLITVGKLKEHYLKDGIAEYSKRIARFAKVELIEVPDEKTPEHASQAQNQQIMAKEGERIADKIGSRDYVIVLAIEGKQLPSETFSKKMSDITLSGYSTITFIIGGSLGLDERIKQRADMAISFGLLTLPHQLMRLVLIEQIYRAFMIQQGSPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPNP_SALPC
Sequence: MLQSNEYFSGKVKSIGFTSSSTGRASVGVMAEGEYTFGTAEPEEMTVVSGALKVLLPGTVEWKVYTAGEVFNVPVHSEFHLQVAEPTSYLCRYL
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: SYL_FRAP2
Sequence: MSEYNFTQIEQQAQEYWRENNSFKAVEDKNKEKFYCLSMLPYPSGTLHMGHVRNYTIGDVIARYQKMQGKNVLHPMGWDAFGLPAENAAIKHKKSPYEWTKSNIAYMRSQLDSLGFSFDWSREVATCDESYYKWEQWFFIQLYKKGLAYRKNSVVNWDPVDQTVLANEQVVDGRGWRSGALIEKKEIPQWFLKITDYADELLKDINQLDGWPEAVKTMQTNWIGKSKGLTVKFKIQNSDKEIEVFTTRPDTLMGVSYLGIAPEHPLALEEAKTNSQLKSFIDECKRISTMEADLATQEKKGFKTSIQAIHPISGETVNVWVANFVLMGYGSGAVMSVPAHDQRDWEFAQKYNIALKQVIKPSDNKSKLDLDKEAFTEKGILINSGEFDGLNFKSAYQAIKKYLFDNDKGYETTNFRIHDWGISRQRYWGCPIPMIHCNDCGLVPEKEENLPVKLPTNVTLTEAGSPLKDIPEFLNVACPNCGKPATRETDTFDTFFESSWYYARYTCPTADKMLSEEANYWLPVDKYIGGIEHAIMHLLYARFFHKLMRDQGLVTSDEPFKNLLTQGMVLKDGAKMSKSKGNTVDPQELIDKYGADTVRLFSMFAAPPEQSLEWSDTGVDGANKFLRKVYNYAYTNKEILAKNITIDVTKLSKNDKKARYEIYANLKQAIFDFDKSQFNTVVSACMKILNTLNNYDNLSDSVKLEGFSILLRILSPFTPHICHYLWQEIGLGEDILHTQFPTVDDIALEKDEFLLVVQINGKVKVKLELDASLTKEQVEQEVLSDEQIKTFIKDKQIVKVIYVPQKLINIVVK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL37A_PYRAE
Sequence: MPFSHTKIVGPAGRYGARYGMGLRRKVTAIEVKQRGKHRCPSCRSLVRLERIAFGIWRCPKCGFTFAGGAWTPQTIMGKALAPEELKEVEAQKAKWKEAVK
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L37Ae, Ribosomal protein L43e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily.
Protein: YM04_YEAST
Sequence: MCGRFALAYDSGDLPQLLRDWNLPVNTPKDASSNSQHPHDEEDTKDQPTVSKDIFKASYNISPTNYSAVYRPDTKAIQFMRWGLVPFWTKDVSQFKTYRTFNARLENLQESKMWMRPCEKKRCAVLMSGYFEWKTVGKKKTPYFISRRDGRLMFVAGMYDYVEKDDLYTFTIITAQGPRELEWLHERMPCVLEPGTESWDAWMDVDKTTWSTEELVKLLKPDYDESKLQFYQVTDDVGKTTNTGERLIKPLLKEDSDMFSVKREKEEALLENDNEQGIDNRGVKGDKSLKGEDVFNQKKSLKRNSYDGLKKNEEQEETTLPEEGSIGDRVKREEANLSPKREGNREKRNIVNMLGNQKDSRGKKKIKK
What is the function of this protein?
Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites.  Recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA: forms a stable thiazolidine linkage between a ring-opened abasic site and the alpha-amino and sulfhydryl substituents of its N-terminal catalytic cysteine residue (By similarity).  Acts as a protease: mediates autocatalytic processing of its N-terminal methionine in order to expose the catalytic cysteine (By similarity).
What are the official names of this protein?
Abasic site processing protein YMR114C.
What is the protein family that this protein belongs to?
Belongs to the SOS response-associated peptidase family.
What are the subcellular locations of this protein?
Note=Localizes to replication forks.
Protein: LE25_SOLLC
Sequence: MQTGKDAASAAKAGMEKTKANVQEKAERMTTRDPLKKEMATEKKEDRVAAAEMGKRDAKAQHAAEKQGAATTGTGTTGYGATGNHTTF
What are the official names of this protein?
Protein LE25.
What is the protein family that this protein belongs to?
Belongs to the LEA type 1 family.
Protein: PINH_ECOLI
Sequence: MWHLVVLLEELCERGINFRALAQSIFAQQWGDECCKSKTICDLKVIV
What are the official names of this protein?
Putative protein PinH, Putative DNA-invertase from prophage CP4-44.
What is the protein family that this protein belongs to?
Belongs to the site-specific recombinase resolvase family.
Protein: LIPM_SYMTH
Sequence: METNWRLLDTGHRPGPENMAIDEAIAMAHGRGEVPPTLRFYGWNPPAVSIGYFQSMLGEVDLDAVRAGGYGYVRRPTGGRLIFHHMELTYSVVIREELLPGGVIETYREISRGLLAGMAELGVPAALSGGDRDPRRADPDGFHTACFDTASAYELQVGGRKVAGSAQTRRDGVILQHGSILLDIDVPLLFRLMRLPEGIPAERLMARFRAKSTTLAEALGRPVSWAEARDAFAAGFARALGLTLTPGQLTEREEKEAQTLVEAKYGCDNWNMRK
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation.
What are the official names of this protein?
Octanoyltransferase LipM, Octanoyl-[acyl-carrier-protein]:[GcvH] N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the octanoyltransferase LipM family.
Protein: ADO1_ORYSJ
Sequence: MEWDSESDGAGSIGAGEEEEEEEEEEEGGFGGGGGGGGGGGGMFSFAIEGMLRASGPCGLVVTDALEPDCPIIYVNCGFEEATGYRAEEVLGRNCRFLQCRGPFAQRRHPLVDAMVVSEIRKCIDNGTEFRGDLLNFRKDGSPLMNKLHLTPIYGDDETITHYMGIQFFTNANVDLGPLPGSLTKEPVRSTRFTPDNFFRPISTGPGQSNFCREYSSLFQLTDEVLCQSILSRLSPRDIASVSSVCRRLYLLTRNEDLWRMVCQNAWGSETTRALETVPAAKRLGWGRLARELTTLEAVAWRKLTVGGAVEPSRCNFSACAVGNRVVLFGGEGVNMQPMNDTFVLDLNASNPEWRHVNVSSAPPGRWGHTLSCLNGSLLVVFGGCGRQGLLNDVFTLDLDAKQPTWREIPGVAPPVPRSWHSSCTLDGTKLVVSGGCADSGVLLSDTYLLDVTMDKPVWREVPASWTPPSRLGHSMSVYGGRKILMFGGLAKSGPLRLRSSDVFTMDLSEEEPCWRCLTGSGMPGAGNPAGAGPPPRLDHVAVSLPGGRVLIFGGSVAGLHSASQLYLLDPTEEKPTWRILNVPGRPPRFAWGHSTCVVGGTKAIVLGGQTGEEWMLTEIHELSLASSTV
What is the function of this protein?
Component of an E3 ubiquitin ligase complex that plays a central role in blue light-dependent circadian cycles.  Acts as a blue light photoreceptor, due to the presence of FMN, that mediates light-regulated protein degradation of critical clock components by targeting them to the proteasome complex (By similarity).
What are the official names of this protein?
Adagio-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the ADAGIO family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RBSA1_BURCM
Sequence: MSRSESSRPLLEMRRISKTFPAVRALDNVSLTVYPGEIHSLMGENGAGKSTLMKILSGAYRADAGGEILIDGERIDVDGPLAARDAGVAVIYQELCLAPNLTVAENIYVGRELRRGNRRWGTIDRAAMARGCEDVLARLGAPFGPDTLVGTLSIAEQQLVEIARAVHTRARILVMDEPTTPLSSRETEHLFGLIRQLREEGLAIIYISHRMAEIYELSDRVSVLRDGSYVGTLERESLSAERLVAMMVGRDISGFYKKEHAPYDPGHLLLSVRDIADAERVRGCSLDLHAGEVLGIAGLVGAGRTELARLIFGAEPRTRGDVKLGDRAFGAHSPRDAIDAGLVYLTEDRKRQGLFLDMSVRDNINISVCNRDARLGALDLARGAQRARDAIASLSIRVPNANVNVGALSGGNQQKVLLSRLLETKPRVLILDEPTRGVDIGAKSEIYRIINELARAGVGVIVISSELPEIIGVADRVLVMREGEIAGELGGHTHTPITQEAIIALATGSQAELADAH
What is the function of this protein?
Part of the ABC transporter complex RbsABC involved in ribose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Ribose import ATP-binding protein RbsA 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RRP41_PYRFU
Sequence: MMLKPEGLKLIDENGRRLDGRKKYELRPIKMKVGVLKNANGSAYIEWGKNKIIAAVYGPREIHPKHLQRPDRAILRVRYNMAPFSVEERKKPGPDRRSIEISKVIRGALEPALILEMFPRTAIDVFIEVLQADAGTRVAGITAASLALADAGIPMRDLVAACSAGKIEGEIVLDLNKEEDNYGEADVPVAIMPIKNDITLLQMDGYLTKEEFIEAVKLAIKGAKAVYQKQREALKEKYLKIAQEVEGSEQ
What is the function of this protein?
Catalytic component of the exosome, which is a complex involved in RNA degradation.  Has 3'->5' exoribonuclease activity.  Can also synthesize heteromeric RNA-tails.
What are the official names of this protein?
Exosome complex component Rrp41.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family. Rrp41 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX1_DORPE
Sequence: IGTLYFMFGIWAGLVGTSLSLMIRTELGKPGSLLNDDQLYNVVVTAHGFIMIFFMVMPIMIGGFGNWLVPLMLGAPDMAFPRMNNMSFWLLPPSLTLLLASSAVESGAGTGWTVYPPLSSNLSHAGPSVDLAIFSLHLAGISSILGAINFITTIMNMRWEGLLMERLSLFVWSVFITAILLLLSLPVLAGAITMLLTDRNFNTTFFDPSGGGDPILYQHLFWF
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.