PharMolix/UniProtQA huggingface dataset:
Protein: SODM_STAXY
Sequence: MAFELPNLPYGFDALEPHIDQQTMEIHHGKHHNTYVTKLNAAVEGTDLESKSIEEIVANLDSVPENIQTAVRNNGGGHLNHSLFWELLTPNSEEKGTVVDKIKEQWGSLDAFKEEFADKAAARFGSGWAWLVVNNGNLEIVTTPNQDNPITEGKTPILGLDVWEHAYYLKYQNKRPDYISAFWNVVNWEKVDELYNAAK
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.  Catalyzes the dismutation of superoxide anion radicals into O2 and H2O2 by successive reduction and oxidation of the transition metal ion at the active site.  Also contributes to the inhibition of lipid oxidation.  Manganese-preferring enzyme, less active with iron than with manganese.
What are the official names of this protein?
Superoxide dismutase [Mn/Fe].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: DCD_COXB2
Sequence: MPIKSDKWIRRMAESHQLIYPFEPKQVRETPSGKVISYGTSSYGYDVRCADEFKIFTNINASIVDPKNFDPNGFIDLKANVCIIPPNSFVLARTVEYFKIPRNILTICLGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTNLPAKIYANEGVAQMLFLESDEVCDISYKDRGGKYQGQKGVTLPVA
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: SEPT7_BOVIN
Sequence: MSVSARSAAAEERSVNSSTMVAQQKNLEGYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSPEYPGPSHRIKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESRVNRRQMPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFKKQIMKEIQEHKIKIYEFPETDDEEENKLVKKIKDRLPLAVVGSNTIIEVNGKRVRGRQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDNNKNKGQLTKSPLAQMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAELQRRHEQMKKNLEAQHKELEEKRRQFEDEKANWEAQQRILEQQNSSRTLEKNKKKGKIF
What is the function of this protein?
Filament-forming cytoskeletal GTPase.  Required for normal organization of the actin cytoskeleton.  Required for normal progress through mitosis.  Involved in cytokinesis.  Required for normal association of CENPE with the kinetochore.  Plays a role in ciliogenesis and collective cell movements.  Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (By similarity).
What are the official names of this protein?
Septin-7, CDC10 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Cleavage furrow. Midbody. Cytoplasm, cytoskeleton, cilium axoneme. Cell projection, cilium, flagellum. Note=Distributed throughout the cytoplasm in prometaphase cells. Associated with the spindle during metaphase. Associated with the central spindle and at the cleavage furrow in anaphase cells. Detected at the midbody in telophase. Associated with actin stress fibers. Found in the sperm annulus (By similarity).
Protein: NADE_HELPY
Sequence: MQKDYQKLIVYLCDFLEKEVQKRGFKKVVYGLSGGLDSAVVGVLCQKVFKENAHALLMPSSVSMPENKTDALNLCEKFSIPYTEYSIAPYDAIFSSHFKDASLTRKGNFCARLRMAFLYDYSLKSDSLVIGTSNKSERMLGYGTLFGDLACAINPIGELFKTEVYELARRLNIPKKILNKPPSADLFVGQSDEKDLGYPYSVIDPLLKDIEALFQTKPIDTETLAQLGYDEILVKNITSRIQKNAFKLELPAIAKRFNPE
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: IOLC_CLOTE
Sequence: MNYIKFDEKKPLDVIPIGRVTIDFNPNEINRPLEESRTFTKYLGGSPGNIAVGLARLGKKVGFLSTVSDDQFGNFVVNYLKNEGIDISQINRAKNGEKLGLTFTEILSPKESSILMYRKGIADLQLSSKEVSEDYIKSAKAIVISGTALSKSPSREAAFVALEYAKKHNTRIIFDLDYREYTWNCKEEIAIYYSLAARMSDVIMGSREEFNLMEGLISPEESNDKETAERWIGYGNKIVVIKHGKDGSTAYLHDGTSYKIKPFPVKLLKSFGGGDAYASAFIYGIMEGWDVIDALEFGSASAAMLVASHSCSEAMPKVEEIKQFIKEKKEEHGEMVVRG
What is the function of this protein?
Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D-gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP).
What are the official names of this protein?
5-dehydro-2-deoxygluconokinase, 2-deoxy-5-keto-D-gluconate kinase, DKG kinase.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family.
Protein: DAPD_DECAR
Sequence: MTHPLQATIEELWERRTELSPQSPPTTIAAINSVIGDLDSGKLRVAEKIAGEWFTHQWIKKAVLLSFRVRDNRVQEAGDIRFYDKVDTKFEGWTEEQFRQGGFRVVPGTIVRKGSYVAKNAVLMPSFVNIGAYVDESTMVDTWVTVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIEDNCFIGARSEVVEGVVIGENSVLSMGVYIGQSTPIYDRETGEVTYGRVPPGSVVISGTLPKADGKYSLYAAIIVKKVDAQTRSKTSINELLRP
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 7DLH_CATRO
Sequence: MELNFKSIIFLVFVSLTLYWVYRILDWVWFKPKKLEKCLREQGFKGNPYRLFLGDQYDSGKLIRQALTKPIGVEEDVKKRIVPHILKTVGTHGKKSFMWVGRIPRVNITDPELIKEVLTKYYKFQKNHHDLDPITKLLLTGIGSLEGDPWAKRRKIINAAFHFEKLKLMLPAFYLSCRDMVTKWDNKVPEGGSAEVDVWHDIETLTGDVISRTLFGSNFEEGRRIFELMKELTALTIDVIRSVYIPGQRFLPTKRNNRMRAIDKEVRVRITEIINKKMKVMKSGEAASAADDFLGILLECNLNEIKEQGNNKSAGMTIGEIIGECKLFYFAGQDTTSTLLVWTMVLLSRFPEWQTRAREEVFQVFGNKTPDYDGISHLKVITMILYEVLRLYTPVAELTKVAHEATQLGKYFIPAGVQLMMPQILLHHDPEIWGEDVMEFKPERFAEGVLKATKSQGSFFPFSLGPRMCIGQNFALLEAKMAMSLILRRFSFELSPSYVHAPFTLITMQPQYGAHLILHKL
What is the function of this protein?
Component of the seco-iridoid and derivatives monoterpenoid indole alkaloids (MIAs, e. g.  vincristine, quinine, and strychnine) biosynthesis pathway.  Catalyzes the conversion of 7-deoxyloganic acid into loganic acid (PubMed:24710322, PubMed:24103035).  Not active on 7-deoxyloganetic acid (PubMed:24710322).
What are the official names of this protein?
7-deoxyloganic acid hydroxylase, Cr7DLH, Cytochrome P450 72A224, CYP72A224.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: RL11_STAHJ
Sequence: MAKKVEKVVKLQIPAGKANPAPPVGPALGQAGVNIMGFCKEFNARTQEQAGLIIPVEISVYEDRSFTFITKTPPAPVLLKKAAGVEKGSGEPNKTKVATVTKDQVREIAQTKMQDLNAADEEAAMRIIEGTARSMGITVQ
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RR3_EUGLO
Sequence: MGQKTNPNGLRFGKFKKHFSCWYTENKNYSHFVKQDIFIRKFLMEKIKNVFISLIEIEKDNKETVIFIHYLNFSKFNKVETNSEKNEINLFKLKNLLLKSLNSFFNVKINFNEFIIKLIEIENPILDVRFIANDIRYKLEKRMNFRKIVNSTIANIINKGIKGIKIKLSGRLNDAEMAREESFREGKVPLNTLKANIDYFHCTAKTLSGSLGIKVWLNK
What are the official names of this protein?
Plastid 30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Plastid.
Protein: EGS1_PETHY
Sequence: MAEKSKILIIGGTGYIGKFVVEASAKAGHPTFVLVRESTVSDPAKGKIVESFNNSGVTILYGDLYDHESLVKAIKQVDVVISTVGQMQLADQTKIIAAIKEAGNIKRFFPSEFGMDVDKVNAVEPAKSTFAIKVQIRRAIEAEGIPYTYVSSNCFAGYFLPTLVQPGATDPPRDKVIISGDGNAKAVFNEEHDIGTYTIKAVDDPRTLNKTLYIKPPKNTLSFNELVAIWEKLIGKTLEKIYIPEEQILKDIATSPIPINIILAINHSTFVKGDQTNFVIEPSFGVEASELYPDVKYTTVEEYLSHFA
What is the function of this protein?
Involved in the biosynthesis of the floral volatile eugenol (PubMed:18208524).  Catalyzes the synthesis of the phenylpropene eugenol from coniferyl acetate (PubMed:18208524).  Phenylpropenes are produced by plants as defense compounds with antimicrobial and antianimal properties, or as floral attractants of pollinators (PubMed:18208524).
What are the official names of this protein?
Eugenol synthase 1, PhEGS1.
What is the protein family that this protein belongs to?
Belongs to the NmrA-type oxidoreductase family.
Protein: CD302_BOVIN
Sequence: MPRAAPPALLLPLLGLAAAAAADCPSSTWVQFQDSCYIFLQEAIKVESIEDVRNQCTNHGADMISIHNEEENAFILDTLKKQWKDPADILLGMFFDTDDASFKWFDNSNMTFNKWSDQEDDEELVDTCAFLHTKTGDWKKGNCEVSSVEGTLCKAAIPYEKKYLSDNRILISALVIASTVILTVLGAVVWFLYKRSLDSGFTTVFSAAHQSPYNDDCVLVVAEENEYDIQFN
What is the function of this protein?
Potential multifunctional C-type lectin receptor that may play roles in endocytosis and phagocytosis as well as in cell adhesion and migration.
What are the official names of this protein?
CD302 antigen, Type I transmembrane C-type lectin receptor DCL-1.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Cell projection, filopodium. Cytoplasm, cell cortex. Cell projection, microvillus. Note=Colocalizes with F-actin in filopodia, cellular cortex and microvilli of the apical cell surface.
Protein: LPXA_CAMC5
Sequence: MKNIHQTAVVEDGARIGEDVKIEAYAFVSKDAVLGDNVTIKQGARVIGNTQIGDNSKIFSYAIVGDIPQDISYHDEENTGVIIGKNATIREFCTINSGTHKGDGLTRIGENAFIMAYCHIAHDCLIGNNIILANNATLAGHVELGDYAVVGGLTPIHQFVKVGESCMIAGASALSQDVVPFCLAEGNRAYIRSLNLVGIRRRFEKEQVEELVKAYKFLFNQGVSLKDQAGELFEKTNDTNVKKMCKFILETTRGIPLAKGRD
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR11_CERDE
Sequence: MTKAIQKIGSRRNGRIASRKNGRRIPKGVIHVQASFNNTIVTVTDVRGQVVSWSSAGTCGFRGTRRGTPFAAQTAAANAIRTVVDQGMQRAEVMIKGPGLGRDAALRAIRRSGILLSFVRDVTPMPHNGCRPPKKRRV
What are the official names of this protein?
30S ribosomal protein S11, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TOPK_HUMAN
Sequence: MEGISNFKTPSKLSEKKKSVLCSTPTINIPASPFMQKLGFGTGVNVYLMKRSPRGLSHSPWAVKKINPICNDHYRSVYQKRLMDEAKILKSLHHPNIVGYRAFTEANDGSLCLAMEYGGEKSLNDLIEERYKASQDPFPAAIILKVALNMARGLKYLHQEKKLLHGDIKSSNVVIKGDFETIKICDVGVSLPLDENMTVTDPEACYIGTEPWKPKEAVEENGVITDKADIFAFGLTLWEMMTLSIPHINLSNDDDDEDKTFDESDFDDEAYYAALGTRPPINMEELDESYQKVIELFSVCTNEDPKDRPSAAHIVEALETDV
What is the function of this protein?
Phosphorylates MAP kinase p38.  Seems to be active only in mitosis.  May also play a role in the activation of lymphoid cells.  When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage.
What are the official names of this protein?
Lymphokine-activated killer T-cell-originated protein kinase, Cancer/testis antigen 84, CT84, MAPKK-like protein kinase, Nori-3, PDZ-binding kinase, Spermatogenesis-related protein kinase, SPK, T-LAK cell-originated protein kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
Protein: RL16_ACHLI
Sequence: MLMPKRTKYRRPHRVSYEGKAKGRNEIINGDFALVAKEGAWITNRQIEAARIAMTREMKRLGKVWINIFPHLAKTKKPMEVRMGSGKGAPDSWVAVVKEGKIMFEINGVSEATAREALRKAGHKLPIKVKIVKRGEEA
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: TTCA_TOLAT
Sequence: MQDLSAKQQYNNNKLQKRLRRHIGQAIADFNMIEEGDRVMVCLSGGKDSFAMLDILRNLQASAPINFDIVAVNLDQKQPGFPPEVLPQYLDSIGVEYKIVEEDTYSIVKEKIPEGKTTCSLCSRLRRGILYRTASELGATKIALGHHRDDILETLMLNMFYAGKLKAMPPKLVSDDGKHVVIRPLAYCHEKDLIRYAEWKEFPIIPCNLCGSQENLQRKAMKEMLNEWDRRFPGRIETMFNAIQNITPSHLMDHKLFDFKSINSSSGVIDGGDIAFDKPDIPAVPQLMVIEPDDRVEIIELN
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THA_ONCMY
Sequence: PEDIGQSPGVPTPDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLSGEMAVKREQLKNGGLGVVSDAIFDLGKSLAQFNLDDSEVALLQAVLLMSSDRSGLTSVDKIEKCQETYLLAFEHYINHRKHNIPHFWPKLLMKVTDLRMIGACHASRFLHMKVECPNELFPPLFLEVFEDQEV
What is the function of this protein?
Nuclear hormone receptor that can act as a repressor or activator of transcription.  High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
What are the official names of this protein?
Thyroid hormone receptor alpha, Nuclear receptor subfamily 1 group A member 1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1196_METJA
Sequence: MGHLTLKDAVFLTITSIVGGGIFVLSPLTYLLFGKSIIWGWALLIFVSLIMASPFAYASTKISESGGVYKFVMKILGREIGVFSAYILWLSGVFALSGVVSFFEIVFNTKFNVSYVGLCLIVILTALILGGLRIVGNFVRIFGILTITIILYIVFSNGIKIDSIGEFNLKNAILTIYFGLWTATGWEGITMPLSAFKNQKAIAYGLLVGTFIIGVLYLLFSLTIVSLNVKTNNLDEILKILIGDNLFLLAGMLLIISSCAFSVLFTLSYMPYGMGKDRIFPKAFIKLRKEIPYYGVILNTLLVIILLIFDAKTLVDMSMFSTLIAYFLLYLAVFKESSGKIKAISLISMLITGLLILFRVYNFIIL
What are the official names of this protein?
Putative amino-acid transporter MJ1196.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FABP_BLOTA
Sequence: MPIEGKYKLEKSDNFDKFLDELGVGFMVKTAAKTLKPTLEVDVQGDTYVFRSLSTFKNTEIKFKLGEEFEEDRADGKRVKTVVNKEGDNKFIQTQYGDKEVKIVRDFQGDDVVVTASVGDVTSVRTYKRI
What is the function of this protein?
FABPs are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.  Binds the natural fluorescent fatty acid cis-parinaric acid and oleic acid by competition, but not retinol, retinoic acid, cholesterol, dansylated or anthroxylated fatty acids such as dansyl-DL-aminocaprylic acid and 12-(9-anthroyloxy)-stereate.
What are the official names of this protein?
Fatty acid-binding protein, Bt6.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRAA_SALG2
Sequence: MKYDTSELCDIYQEDVNVVEPLFSNFGGRSSFGGQIITVKCFEDNGLLYDLLEQNGRGRVLLVDGGGSVRRALVDAELARLATQNEWEGLVIYGAVRQVDDLEELDIGIQAIAAIPVGAAGEGIGESDVRVNFGGVTFFSGDHLYADNTGIILSEDPLDIE
What is the function of this protein?
Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity.  Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.  Modulates RNA-binding and helicase activities of the degradosome.
What are the official names of this protein?
Regulator of ribonuclease activity A.
What is the protein family that this protein belongs to?
Belongs to the RraA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURI_HALOH
Sequence: MRIGIFDSGVGGITVLKEALNLLPGEDYIYYADTANVPYGTKDKNEVRQYIFKAVEFLINRGIEALVVACNTATSIAIKDLRETYQFPIVGMEPAVKPAVERSRNKKVLVLATPLTIREEKFRNLVSRVKAEDIVDSLGLPGLVEYAEGFVFDENIIIPYLKDRLSPFNLQEYGTLVLGCTHFLYFRDIFNKIIPDHIDIIDGNKGTVRHLKNLLLQSGFKTGSEGSGEIIFYSSGKKDERRLKKYLDILKEI
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: YR549_MIMIV
Sequence: MSNPCLTMNITKDNLKFFVLNGKYILESNNDMMFAINTKRIIADKYDFGIIINSSIYNKYLQNIGCPLYSPTEIFNYYQLIVNHQFTQADGKLFEDRIKFIFVNLETICDRSNYTDFVSWYLTVIDDIDNYKNVFIVINELNVQDDIDSENMDDLDDMDHYVSNFLNLLLATVNKNTYVLSSDSEYFAHVSLYGKISCDESLNMILCGNIFDNSDCKYFLTNGTSYKFFNGYFVIHRSDNLSGFVGITKDSKNINIDYHYLNMLTVSQIVVHSVIRLLEGYKSSDKKNEVDLYLLRSYHSYIEQNGLISIYKNNLANKNIRSYFLKCKVIDDVMIELTNLLE
What are the official names of this protein?
Uncharacterized protein R549.
Protein: BR1C_LITSH
Sequence: FFPIVAGVAGQVLKKIYCTISKKC
What is the function of this protein?
Antibacterial activity against Gram-negative bacterium E. coli.
What are the official names of this protein?
Brevinin-1Sc.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
Protein: CHFR_DANRE
Sequence: MTNQDSDQAWGKLVKVDASPGSEIVLINSECTVGRKKDCDLSFPANKLVSGNHCKITHDQNSGKVWLEDMSTNGTVINMSKVVKKQTHLLQNGDVIYFVYRKNEPEQNIAYVYQSITPQESASHDVEDAGREEDSDLTETESEPAPVEPVIVKPLPQSGHEDPQPSTSSSSLHFYNMPLSTCSDVSARKNPVSSSAVCKGDSTSSGSPAQTRLKWTCWTDGEPEEEMQRKRRKTDRDDPGFGSAHSDASADIPLRGASGKEKTEGATTDKMEESLTCIICQDLLYDCISVQPCMHTFCAACYSGWMERSSFCPTCRCPVERIRKNHILNNLVEAYLLQHPEKCRTEDDLRSMDARNKITQDMLQPKVERSFSDEEASSDYLFELSDNDSDISDMSQPYMMCRQCPGYRKELSSALWICESAQSESLAKTAGDGPSTSSDSTTAAPQEFRCPPQASHLICTCCLQPMPDRRFEHLPPQVSPQHCLVCQKPFCHVYWGCPRIGCHGCLARFSELNLNDKCLDGVFNGNQYESEVLQNYLSCRGMSWRHLLQDSLQALQQGLYHLSDYRITANSFLCYCCGLRTFRELAYKYRERIPPSELPDAVTNRPNCYWGRNCRTQVKAHHALKFNHICEQTRFKN
What is the function of this protein?
E3 ubiquitin-protein ligase that functions in the antephase checkpoint by actively delaying passage into mitosis in response to microtubule poisons.  Acts in early prophase before chromosome condensation, when the centrosome move apart from each other along the periphery of the nucleus.  Probably involved in signaling the presence of mitotic stress caused by microtubule poisons by mediating the 'Lys-48'-linked ubiquitination of target proteins, leading to their degradation by the proteasome.  May also promote the formation of 'Lys-63'-linked polyubiquitin chains and functions with the specific ubiquitin-conjugating ubc13-mms2 (ube2n-ube2v2) heterodimer.  Substrates that are polyubiquitinated at 'Lys-63' are usually not targeted for degradation, but are rather involved in signaling cellular stress.
What are the official names of this protein?
E3 ubiquitin-protein ligase CHFR, Checkpoint with forkhead and RING finger domains protein, RING-type E3 ubiquitin transferase CHFR.
What is the protein family that this protein belongs to?
Belongs to the CHFR family.
What are the subcellular locations of this protein?
Nucleus, PML body.
Protein: PETN_LOTJA
Sequence: MDIVSLAWAALMVVFTFSLSLVVWGRSGL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 8, Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PetN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: TRPD_IDILO
Sequence: MKALQTLMSGESLTQDQTREFFQRLIKGELNDIQVSAALIAMKMRGETPAELAGAAEAILSAAKPFLRSDTTVIDSCGTGGDGSNTINISTTAALVAASMGLAVAKHGNRSVSSRSGSADVLEALKLRVNLDPSDASTQLADNGFCFLFAPHYHPGIKHAMPVRQTLKTRTLFNLIGPLVNPARPDAQLLGVYSEEWVRPMAETLQRLGVKRAMVVHGSGLDELALHGPTRVIELRNGELNDYHVTPNDFGVPSAPLDELKGGDADFNARILEDILAGGGSPAQRHSVAMNVAALLYLSGQYNDMKAATAATMEHLDTGQPLLHLRRVQDAQETYHV
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: GCS2_DECAR
Sequence: MTTKALGDFKDSAAFSLGVELELQLVSKRDFDLTRGATDLLGSLDYDERFGEIKLEITESMIEISTQPQSTVDGIAADLSGLRDTLRQHCERNNIGICGGGTHPFHHWPERRICPGDRFNDLYQRYGYLAKQFTVFGQHVHIGCTSADEAIWLTQAFGVYVPAFIALSASSPFVDGVDSFYQSARLNAVSAFPLSGQCPPLGSWQEFTEHFAFLQACGIAQSIKDLYWDVRPKPEFGTVEIRVCDTPLTIEQATSLAALAQSLARWLLRTRPPLHTAKQAHVARYNKFQACRYGFEAMISDPVNLCQTPLKQTLADLLEAVSEDARELDCADWLSPLKQAVAENTGDAAWLRARENQHGNLNDVVREASKRLMGKNDQFQEKTK
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: TASY_TAXBR
Sequence: MAQLSFNAALKMNALGNKAIHDPTNCRAKSERQMMWVCSRSGRTRVKMSRGSGGPGPVVMMSSSTGTSKVVSETSSTIVDDIPRLSANYHGDLWHHNVIQTLETPFRESSTYQERADELVVKIKDMFNALGDGDISPSAYDTAWVARLATISSDGSEKPRFPQALNWVFNNQLQDGSWGIESHFSLCDRLLNTTNSVIALSVWKTGHSQVQQGAEFIAENLRLLNEEDELSPDFQIIFPALLQKAKALGINLPYDLPFIKYLSTTREARLTDVSAAADNIPANMLNALEGLEEVIDWNKIMRFQSKDGSFLSSPASTACVLMNTGDEKCFTFLNNLLDKFGGCVPCMYSIDLLERLSLVDNIEHLGIGRHFKQEIKGALDYVYRHWSERGIGWGRDSLVPDLNTTALGLRTLRMHGYNVSSDVLNNFKDENGRFFSSAGQTHVELRSVVNLFRASDLAFPDERAMDDARKFAEPYLREALATKISTNTKLFKEIEYVVEYPWHMSIPRLEARSYIDSYDDNYVWQRKTLYRMPSLSNSKCLELAKLDFNIVQSLHQEELKLLTRWWKESGMADINFTRHRVAEVYFSSATFEPEYSATRIAFTKIGCLQVLFDDMADIFATLDELKSFTEGVKRWDTSLLHEIPECMQTCFKVWFKLMEEVNNDVVKVQGRDMLAHIRKPWELYFNCYVQEREWLEAGYIPTFEEYLKTYAISVGLGPCTLQPILLMGELVKDDVVEKVHYPSNMFELVSLSWRLTNDTKTYQAEKARGQQASGIACYMKDNPGATEEDAIKHICRVVDRALKEASFEYFKPSNDIPMGCKSFIFNLRLCVQIFYKFIDGYGIANEEIKDYIRKVYIDPIQV
What is the function of this protein?
Catalyzes the cyclization of the ubiquitous isoprenoid intermediate geranylgeranyl diphosphate to taxa-4,11-diene, the parent olefin with a taxane skeleton.
What are the official names of this protein?
Taxadiene synthase, Taxa-4(5),11(12)-diene synthase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: EIN3_ARATH
Sequence: MMFNEMGMCGNMDFFSSGSLGEVDFCPVPQAEPDSIVEDDYTDDEIDVDELERRMWRDKMRLKRLKEQDKGKEGVDAAKQRQSQEQARRKKMSRAQDGILKYMLKMMEVCKAQGFVYGIIPENGKPVTGASDNLREWWKDKVRFDRNGPAAITKYQAENNIPGIHEGNNPIGPTPHTLQELQDTTLGSLLSALMQHCDPPQRRFPLEKGVPPPWWPNGKEDWWPQLGLPKDQGPAPYKKPHDLKKAWKVGVLTAVIKHMFPDIAKIRKLVRQSKCLQDKMTAKESATWLAIINQEESLARELYPESCPPLSLSGGSCSLLMNDCSQYDVEGFEKESHYEVEELKPEKVMNSSNFGMVAKMHDFPVKEEVPAGNSEFMRKRKPNRDLNTIMDRTVFTCENLGCAHSEISRGFLDRNSRDNHQLACPHRDSRLPYGAAPSRFHVNEVKPVVGFPQPRPVNSVAQPIDLTGIVPEDGQKMISELMSMYDRNVQSNQTSMVMENQSVSLLQPTVHNHQEHLQFPGNMVEGSFFEDLNIPNRANNNNSSNNQTFFQGNNNNNNVFKFDTADHNNFEAAHNNNNNSSGNRFQLVFDSTPFDMASFDYRDDMSMPGVVGTMDGMQQKQQDVSIWF
What is the function of this protein?
Transcription factor acting as a positive regulator in the ethylene response pathway, by promoting histone acetylation in an ENAP1-dependent manner, thus accelerating the expression of ethylene-responsive genes (PubMed:28874528).  Binds DNA (PubMed:26352699).  Is required for ethylene responsiveness in adult plant tissues.  Binds a primary ethylene response element present in the ETHYLENE-RESPONSE-FACTOR1 promoter with consequence to activate the transcription of this gene.
What are the official names of this protein?
Protein ETHYLENE INSENSITIVE 3.
What is the protein family that this protein belongs to?
Belongs to the EIN3 family.
What are the subcellular locations of this protein?
Nucleus.