PharMolix/UniProtQA huggingface dataset:
Protein: SYP_XYLFA
Sequence: MRLSEFHLHTTKEIPADAELVSHRLMLRAGMIRKLASGLYTWSPLGLRVLRKVEAIVRDEMNRAGAVEMLLPTIQPRELWEESERWEKFGNQLLKIKDRKQAEYCYSPTAEEAVTDYVRQELTSYKQLPVNLYQIQTKFRDEIRPRFGVMRAREFVMKDAYSFHLNDADLVREYENMRATYTRIFTRLGLEFRAVQADSGAIGGDASQEFHVIADSGEDVLAFSTGSDYAANIEAAIAATPGPRLTANETLQKVSTPTQKRCEDVAALLDIPLQRVVKSIAVMTDSGFFLALLRGDHTLNDIKLSKLPGLANFRLANEVEIARHLGSEPGFLGPVCPGMPIRIIADCEVAVMADFVVGANEVGFHLVGVNWGRDLPEPEVVADIRNVIEGDRAVDGGKICIARGIEVGHVFQLGRKYAEAMKATVLDEYGKAVTMTMGCYGIGVSRIVAAAIEQNHDVAGIIWPASIAPWQVAVCVINPKKDPVITAAAEVLLAELQSADVDTVLDDRGLRPGVMFADMELIGIPHRIVVSERGLAAGTYEYRARHTAMVENLDKTTLLMRIKA
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIPIN_XENLA
Sequence: MMDPLDNGLFDLPDYEHTEDENFPPLPPPHSPGADDEAEDVANGDDWTENAGQTQREEAPKPARRVVKRPQPKLDGQRLASQRGLPALRHMFDDVKFKGKGHETEDLKILLRQMENWAHRLFPKLQFEDFLNRLESMGNKKEVQTCLKKIRMDLPIVHDDFLSEEVVVQTEDHAIDMPSEDFSFPDELHVPSPSQPVKVDLSEETLQRIERNRRLALERRMEKMQAQAESQALSQATQSDPNEIPDDAFDAEMLDAVESMTGIPTASQSPPHVDKDLSLVLHSHDLPVQDVSQSPAPCPKPQGDAPPEKALSLVHSALPSTSDPTSPRKPLTEQLPDDADTSSATPYTEAPACTNTKEEY
What is the function of this protein?
Plays an important role in the control of DNA replication and the maintenance of replication fork stability.  Important for cell survival after DNA damage or replication stress.  May be required for the replication checkpoint induced by hydroxyurea or ultraviolet light (By similarity).
What are the official names of this protein?
TIMELESS-interacting protein, XTipin.
What is the protein family that this protein belongs to?
Belongs to the CSM3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CH082_MOUSE
Sequence: MWPPSGAVRNLALVLARSQRARTCSGVERVSYTQGQSPEPRTREYFYYVDHQGQLFLDDSKMKNFITCFKDLQFLVTFFSRLRPNHSGRYEASFPFLSLCGRERNFLRCEDRPVVFTHLLASDSESPRLSYCGGGEALAIPFEPARLLPLAANGRLYHPAPERAGGVGLVRSALAFELSACFEYGPSSPTVPSHVHWQGRRIALTMDLAPLLPAAPPP
What are the official names of this protein?
UPF0598 protein C8orf82 homolog.
What is the protein family that this protein belongs to?
Belongs to the UPF0598 family.
Protein: LDH_BACVZ
Sequence: MMNERVNKVALIGAGFVGSSYAFALINQGITDELVIIDVNREKAMGDVMDLNHGKAFAPHPVKTSYGTYEDCKDADIVCICAGANQKPGETRLELVEKNLAIFKSIVGEVMASGFDGIFLVATNPVDILTYATWTFSGLPKERVIGSGTTLDSARFRYMLSEYFGAAPQNVHAHIIGEHGDTELPVWSHANIGGVPVQQLLEKHAAYKQDELDQIVDDVKNAAYHIIEKKGATYYGVAMSLARITKAILRNENSILTVSTYLDGQYGVNDVFIGVPAVVNRNGIAGVTELELNETEQAQFSRSANVLKDILAPHFAE
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECF_SYNY3
Sequence: MYLKKLYLRAFRNYLEEEVEFSAQKTILVGNNAQGKSNLLEAVELLATLKSHRTSRDQELVLDGAANGQIKALLERQYSVAELEIDLRRSGRRNLRINQNQCRRQLDFLGCLNAVEFSCLDLDLVRGAPDCRRQWLDTLLTQLEPLYAHLLGQYQHIVKQRNALLKSLRQQWETGLALGEESTASLSLWDQQLVEMGTRVVRRRARGLARLAPLAQEWHGRISGGNETLTVTYQPNVTWVGDDPEVVHQAFLEKLAQRRSAELHLGTTVVGPHRDEVGFVLDDTPARTYGSQGQQRTLVLALKLAELSLIETVIGEPPLLLLDDVLAELDLDRQGQLLMAIEDRFQTLITTTHLSRFDDRWRRSAQILKVNAGQLEERWPSEID
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP (By similarity).
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR7_STAAW
Sequence: MTLLYEGKAKRIFSTNQENELRVEYKDEVTAGNGAKKDTMAGKGRLNNQITSIIFKYLQENGIESHFIKQLSETEQLVKPVKIIPLEVVVRNIASGSITKRLGFENGEVFREPLVEFFYKNDALNDPLITDDHVKLLNIASDEDIEILKSKALKINNVLKQLMDAMNLKLVDFKIEFGKTETGQILLADEISPDTCRIWDKATNANFDKDVYRNNTGSLIETYQIFLNKLEDLK
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: RL2_LEUMM
Sequence: MAIKSYKPTSAGRRNMTTSDFAEITKTTPEKSLLAKKSKTGARNASGRMTVRHHAGGHKQAYRIVDFKRTKDDKTATVKAIEYDPNRTANIALLVYEDGIKSYILAPKGLKVGDKVQSGPDADIKPGNALPLSAIPEGTLIHNIELKPGKGGQLARSAGASAQILGRDGKYIIVRLTSGEVRLVLATNRATIGEVGNAEHSLINWGKAGRNRWRGKRPHVRGSVMNPNDHPHGGGEGKAPVGRPSPMSPWGKKTAGKKTRDKKKASTKFIVRGRKSK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: DPOL_ADE07
Sequence: MQEATEPPPPKRKNKGTVVAPKGHGTLQAIDISTNGPVEIKYHLNLPHALEKIMQVNLLTLPTNLTPQRLRTLDSSGLRALVLELRPCRAEVWTCLPRGLVSMTTIETEDGHADADNIVEREVQAPSLNFPLKFLVKGSQVQLIHEVHPVNRCEYCGRLYKHKHECSARRREFYFHHINSHSSNWWQEIQFFPIGSHPRTERLFLTYDVETYTWMGSFGKQLIPFMLVMKLSGDQRLVNIAYDIAMKLKWDRWRQDPQTFYCITPEKMAVGQHFRQYRDQLQTALAVDLWSSFLKANPHMHEWALEHYALTDPTDLTFEELKKLPHVRGTPRFLELYIVGHNINGFDEIVLAAQVINNRAEVPQPFKITRNFMPRAGEILFNDVTFALPNPAYKKRADFQLWEQGACDDIDFKYQFLKVMVRDTFALTHTSLRNAAQAYSLPVEKGCCPYKAVNQFYMLGSYRAEKDGFPLEEYWKDHEEYLLNRELWEKKSQPRYDIIQETLNYCALDVLVTAELVAKLQESYAHFIRDSVGLPHVHFNIFQRPTISSNSHAIFRQIVYRAEKPNRTNLGPGLLAPSHELYDYVRASIRGGRCYPTYIGILEEPLYVYDICGMYASALTHPMPWGTPLNPYERALAVREWQMTLDDPATISYFDKDLLPGIFTIDADPPDEFMLDPLPPFCSRKGGRLCWTNEPLRGEVATTVDLITLHNRGWRVRIVPDELTTIFPEWKCVAREYVQLNIAAKERADKEKNQTMRSIAKLLSNALYGSFATKLDNKKIVFSDQMDESLIKGISAGTVNIKSSSFLETDNLSAEVMPAFEREYLPQQLALLDSDPEDSEDEQRSAPFYTPPAGTPGHVAYTYKPITFLDVEEGDMCLHTVEKVDPLVDNDRYPSHVASFVLAWTRAFVSEWAGFLYEEDRGTPLEDRPIKSVYGDTDSLFVTQRGHELMETKGKKRIKKHGGKLVFDPDEPDLTWLVECETVCVSCGADAYSPESIFLAPKLYALKCIYCPACHKTSKGKLRAKGHAAEALNYELMVNCYLADMQGADRQRFSTSRMSLKRTLASAQPGAHPFTVTETTLTRTLRPWKDRTLAALDAHRLIPYSRSRPNPRNEEVCWIEMP
What is the function of this protein?
Eukaryotic-type DNA polymerase involved in viral genomic replication.  DNA synthesis is protein primed, and acts in a strand displacement replication.  Assembles in complex with viral pTP, DBP, host NFIA and host POU2F1/OCT1 on viral origin of replication.  The polymerase covalently transfers dCMP onto pTP, thereby initiating complementary strand synthesis.
What are the official names of this protein?
DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: HIR2_DEBHA
Sequence: MRVLVFPSVLHSGQIHSIDINKDNSKILTSGLDKEINVWNLQEFVQLTTEGKDTVKDDIENVKPLLRITAHEDLVNIVKWCPQNENVFVSGDIQGKVYMHDISKNTHELIFPFGWKEDGTSRVVDLAWSDDGRMLAWSSGDCKIHIYDTEKATYQELTSLSNLEKLTVQRSIAFDPTNHYLISMGDDTSIYLYQYQYEPTTRNYQFRLINRISKLINKTSMNVDYKRISWSPDGEYVSVPTASKNQTSLISLLSRSNGWNNILSLVGHNLDCEVVQYNPMIYNSSENNDNPKLFNVIATAGSDMTLVVWNTTKDKPIFILQEISKKPIVDLCWDKTGNSLFVASLDGHLSIVSFHPQELGNTVSEELWKELFEAGEASIKPFNEKPDQDITPSTKKSSHNVIDILDQKNSINVHEAKAKKPTEGIKDLSSISPEEENADTESPLKQDLQAHDKQVTNFVPEVIPAIIEDAPETQTEDILHSAMSTTRSTKSQVKNPKEKPTKVTPEKAKVTTKNGKKRIQPMLISSMNENSSNNSVKKSNTSESNGTSNLVSSGKVLMEFDKPSYSISDDLYKQNKRTKTQDENSNKKLKRELEPVKFIGSVVLNPSTTFARIRLSIPKIRLNFQLSSTVEDNSFILDVKNGLGNETKPSRITYFKKEKQIWCDFIPRFIQLVAEGSTFWAVSTADGQILTYSHTSGKKLLPPIILGSPLSFLESHGNFLMAVTSIGELYVWNIEQKKIHLQSPSSLSSLLDLSNKYQEDGLSKSDNITMCSITNNGIPLITLSNGAGYLFNKDLGTWQTISESWWAFGSHYWDSLGNDDGSKPQSYGLFCDSNDSSIVGLLEQKTNESILRKTRAGRGKYFNKISKNMLMKEGFENLENTISLSHLENRILCCELLGEFKDFHDFFIIYVKRICELGFKAKLFEVCDQLLGPSEPNSTATKDGEANWNSEICGIKKHDLLKEVILSCAKNRDCQRILIHFGKKIGVIDIDEFN
What is the function of this protein?
Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.
What are the official names of this protein?
Protein HIR2.
What is the protein family that this protein belongs to?
Belongs to the WD repeat HIR1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PURA_EDWI9
Sequence: MGKNVVVLGTQWGDEGKGKVVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVVSIIANGVVLAPDALLREMTELEARGVPVRERLLLSEACPLILPYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKASFAVKLKEIMEYHNFQLVNYYHVDAVDYQSVLDEVMAVADLLTSMVVDVADLLNKAYRNGEYVMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGIGPRCVDYVLGIVKAYSTRVGAGPFPTELFDSVGEFLCEKGNEFGATTGRRRRTGWLDAVAVRRAVELNSLSGFCLTKLDVLDGLDEVKICVGYRLPDGREVDVTPLAAEGWEGIEPIYEVLPGWKESTFGVKLRDGLPQAALNYIKRIEEVTGVPVDIISTGPDREETIVLRHPFDA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_THEP1
Sequence: MWKHVKQVDPEIYEVLVNELKRQEYGLELIASENFASLAVIETMGSMLTNKYAEGYPQKRYYGGCEWVDRAEELAIERAKRLFGAKFANVQPHSGSQANMAVYLALAQPGDTIMGMSLSHGGHLTHGAPVNFSGKIFKVVPYGVNLETETIDYDEVRRLALEHKPKIIVAGGSAYARIIDFKRFREIADEVGAYLMVDMAHFAGLVAAGIHPNPLEYAHVVTSTTHKTLRGPRGGLILTNDPDIAKAVDKTIFPGIQGGPLMHVIAAKAVCFKEAMTEEFKEYQKQVVKNAKKMAEEFQKRGYRIVSGGTDTHLFLVDLTPKDITGKAAEKALESCGITVNKNTIPNEKRSPFVASGIRIGTPAVTTRGMKEEEMEEIAEMIDLVLSNVTDENGTVKPEVREEVSKRVRELCERFPLYRDKIEGVEI
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WDR76_RHIFE
Sequence: MSGSCAAAEEKEGSRQRLQMKVNEYKENQNMSSVSLRSIQKTVLEKTVKVCLVPFSLSNYKSGQFKLPKSLLDKNSKNEVACKKYKKTEIKKACTRILTSKMEATASSKAESTLQKSSIDVHTENNQRQHKSTSDTVSLGVDTESSQDGDSDEDTTSSLDDFSGLSPYERKRLKNISENANFFASLQLSESAARLREMIEKRQPPETKRKKPKKKENETGCRRSMRLLNVDPSGVSLPVTPTEPTLVADENPLLPPGPLEMIPENRDDNSELFKEFLQTWAEVSKTSSKNIEKELSSLKTYKANLSGMVISEDTVYKVTKGAIFSIAFHPSEIKTLVAAGAKSGQVGLWDLTHQPKEDGVYVFQPHSQPVSCLYFSPANPAHMLSLSYDGTLRCGDISSAVFEEVYRNERSSLSSFDFLAEDASTFIVGHWDGSISLVDRRTPGASYEKLISSSLRKIRTVHVHPVQRQYFITAGLRDTHIYDARRLTPSGSQPLISLTEHTKSIASAYFSPLTGNRIVTTCADCKLRFFDSSCISSQIPLLTTIRHNTITGRWLTRLRAVWDPKQEDCVIIGSMAHPRQVEIFHETGEQVHSFLGGECLVSVCSINAVHPTRYILAGGNSSGKIHVFMN
What is the function of this protein?
Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.
What are the official names of this protein?
WD repeat-containing protein 76.
What is the protein family that this protein belongs to?
Belongs to the WD repeat DDB2/WDR76 family.
Protein: RECO_PROMH
Sequence: MEGWQRAFVIHARPYSETSLLLDFFTENEGRVRILSKGARGRRSPLKGALQPFTPLLIRWSGRGEIKTLRDAEPISLALPLTGTVLYSGLYLNELLSRVLENGTSYSTLFFEYLSCLQILAASETTPEAALRRFELALLTQLGYGLDFLHCAGSGEPVSDTMTYRYREEKGFIASLVVDHYSFTGLELKSLAKREFPTAGTLKAAKRFTRMALKPYLGGKPLKSRELFRQFAIKKCAKKSVLIEDK
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: SACA1_PIG
Sequence: MSPGGAGCSAGLLLTVGWLLLAGLQSTCGINVTAVQDPSLVSEGENEGEEEAENDSEVENEPQAEAEQDVSNKTVVKEVEFGMCTVTCGVGIREVLLTNGCPGGESKCIVRVEECRGPVDCGWGKPISENLESVRLSCVHTSPVNRFKYVWRLLRPNQQAVILANDSAILEVQRETHPMAFQCETLDNNEIVATVKFTVYTTAELQMKRSSRPDTDAVLVFVLTIGVIICIFVIFVLIFIIVNWATVKDFWASKASTTEIQSELSSMKYKDSTSLDQSPTEIPGHEDDALSEWNE
What is the function of this protein?
Plays a role in acrosome expansion and establishment of normal sperm morphology during spermatogenesis.  Important for male fertility.
What are the official names of this protein?
Sperm acrosome membrane-associated protein 1.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, acrosome inner membrane; Single-pass type I membrane protein. Note=Primarily found in the equatorial segment of the acrosome (PubMed:18448843). The tyrosine phosphorylated protein localizes to a smaller region within the equatorial segment (PubMed:18448843). Also expressed weakly in the principal segment (By similarity).
Protein: CMOA_ECOLC
Sequence: MSHRDTLFSAPIARLGDWTFDERVAEVFPDMIQRSVPGYSNIISMIGMLAERFVQPGTQVYDLGCSLGAATLSVRRNIHHDNCKIIAIDNSPAMIERCRRHIDAYKAPTPVDVIEGDIRDIAIENASMVVLNFTLQFLEPSERQALLDKIYQGLNPGGALVLSEKFSFEDAKVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVETHKARLHKAGFEHSELWFQCFNFGSLVALKAEDAA
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: DUT_DICNV
Sequence: MIAVPYKILDPRLGGEIPLPTYATSGSAALDIRAVFAEESIVLAADECRLIGSGLAFHIADPNYCGIVLPRSGLGYKHGIVLGNLVGLIDSDYQGELKIPLWNRSQTPYTVTLGERIAQLLFLPIAQAQLFPVESFDQKQSTRGSGGFGHTGRF
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: GNAS2_BOVIN
Sequence: MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQDDYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs).  Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP (PubMed:2022671, PubMed:9395396, PubMed:11087399, PubMed:15591060, PubMed:16766715, PubMed:19243146).  GNAS functions downstream of several GPCRs, including beta-adrenergic receptors.  Stimulates the Ras signaling pathway via RAPGEF2 (By similarity).
What are the official names of this protein?
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Adenylate cyclase-stimulating G alpha protein.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family. G(s) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: YEEJ_ECOLI
Sequence: MATKKRSGEEINDRQILCGMGIKLRRLTAGICLITQLAFPMAAAAQGVVNAATQQPVPAQIAIANANTVPYTLGALESAQSVAERFGISVAELRKLNQFRTFARGFDNVRQGDELDVPAQVSEKKLTPPPGNSSDNLEQQIASTSQQIGSLLAEDMNSEQAANMARGWASSQASGAMTDWLSRFGTARITLGVDEDFSLKNSQFDFLHPWYETPDNLFFSQHTLHRTDERTQINNGLGWRHFTPTWMSGINFFFDHDLSRYHSRAGIGAEYWRDYLKLSSNGYLRLTNWRSAPELDNDYEARPANGWDVRAESWLPAWPHLGGKLVYEQYYGDEVALFDKDDRQSNPHAITAGLNYTPFPLMTFSAEQRQGKQGENDTRFAVDFTWQPGSAMQKQLDPNEVAARRSLAGSRYDLVDRNNNIVLEYRKKELVRLTLTDPVTGKSGEVKSLVSSLQTKYALKGYNVEATALEAAGGKVVTTGKDILVTLPAYRFTSTPETDNTWPIEVTAEDVKGNLSNREQSMVVVQAPTLSQKDSSVSLSTQTLNADSHSTATLTFIAHDAAGNPVVGLVLSTRHEGVQDITLSDWKDNGDGSYTQILTTGAMSGTLTLMPQLNGVDAAKAPAVVNIISVSSSRTHSSIKIDKDRYLSGNPIEVTVELRDENDKPVKEQKQQLNNAVSIDNVKPGVTTDWKETADGVYKATYTAYTKGSGLTAKLLMQNWNEDLHTAGFIIDANPQSAKIATLSASNNGVLANENAANTVSVNVADEGSNPINDHTVTFAVLSGSATSFNNQNTAKTDVNGLATFDLKSSKQEDNTVEVTLENGVKQTLIVSFVGDSSTAQVDLQKSKNEVVADGNDSVTMTATVRDAKGNLLNDVMVTFNVNSAEAKLSQTEVNSHDGIATATLTSLKNGDYRVTASVSSGSQANQQVNFIGDQSTAALTLSVPSGDITVTNTAPQYMTATLQDKNGNPLKDKEITFSVPNDVASKFSISNGGKGMTDSNGVAIASLTGTLAGTHMIMARLANSNVSDAQPMTFVADKDRAVVVLQTSKAEIIGNGVDETTLTATVKDPSNHPVAGITVNFTMPQDVAANFTLENNGIAITQANGEAHVTLKGKKAGTHTVTATLGNNNTSDSQPVTFVADKASAQVVLQISKDEITGNGVDSATLTATVKDQFDNEVNNLPVTFSSASSGLTLTPGVSNTNESGIAQATLAGVAFGEKTVTASLANNGASDNKTVHFIGDTAAAKIIELAPVPDSIIAGTPQNSSGSVITATVVDNNGFPVKGVTVNFTSNAATAEMTNGGQAVTNEQGKATVTYTNTRSSIESGARPDTVEASLENGSSTLSTSINVNADASTAHLTLLQALFDTVSAGETTSLYIEVKDNYGNGVPQQEVTLSVSPSEGVTPSNNAIYTTNHDGNFYASFTATKAGVYQLTATLENGDSMQQTVTYVPNVANAEITLAASKDPVIADNNDLTTLTATVADTEGNAIANTEVTFTLPEDVKANFTLSDGGKVITDAEGKAKVTLKGTKAGAHTVTASMTGGKSEQLVVNFIADTLTAQVNLNVTEDNFIANNVGMTRLQATVTDGNGNPLANEAVTFTLPADVSASFTLGQGGSAITDINGKAEVTLSGTKSGTYPVTVSVNNYGVSDTKQVTLIADAGTAKLASLTSVYSFVVSTTEGATMTASVTDANGNPVEGIKVNFRGTSVTLSSTSVETDDRGFAEILVTSTEVGLKTVSASLADKPTEVISRLLNASADVNSATITSLEIPEGQVMVAQDVAVKAHVNDQFGNPVAHQPVTFSAEPSSQMIISQNTVSTNTQGVAEVTMTPERNGSYMVKASLPNGASLEKQLEAIDEKLTLTASSPLIGVYAPTGATLTATLTSANGTPVEGQVINFSVTPEGATLSGGKVRTNSSGQAPVVLTSNKVGTYTVTASFHNGVTIQTQTTVKVTGNSSTAHVASFIADPSTIAATNTDLSTLKATVEDGSGNLIEGLTVYFALKSGSATLTSLTAVTDQNGIATTSVKGAMTGSVTVSAVTTAGGMQTVDITLVAGPADTSQSVLKSNRSSLKGDYTDSAELRLVLHDISGNPIKVSEGMEFVQSGTNVPYIKISAIDYSLNINGDYKATVTGGGEGIATLIPVLNGVHQAGLSTTIQFTRAEDKIMSGTVSVNGTDLPTTTFPSQGFTGAYYQLNNDNFAPGKTAADYEFSSSASWVDVDATGKVTFKNVGSNSERITATPKSGGPSYVYEIRVKSWWVNAGEAFMIYSLAENFCSSNGYTLPRANYLNHCSSRGIGSLYSEWGDMGHYTTDAGFQSNMYWSSSPANSSEQYVVSLATGDQSVFEKLGFAYATCYKNL
What are the official names of this protein?
Uncharacterized protein YeeJ.
What is the protein family that this protein belongs to?
Belongs to the intimin/invasin family.
Protein: WWP1_HUMAN
Sequence: MATASPRSDTSNNHSGRLQLQVTVSSAKLKRKKNWFGTAIYTEVVVDGEITKTAKSSSSSNPKWDEQLTVNVTPQTTLEFQVWSHRTLKADALLGKATIDLKQALLIHNRKLERVKEQLKLSLENKNGIAQTGELTVVLDGLVIEQENITNCSSSPTIEIQENGDALHENGEPSARTTARLAVEGTNGIDNHVPTSTLVQNSCCSYVVNGDNTPSSPSQVAARPKNTPAPKPLASEPADDTVNGESSSFAPTDNASVTGTPVVSEENALSPNCTSTTVEDPPVQEILTSSENNECIPSTSAELESEARSILEPDTSNSRSSSAFEAAKSRQPDGCMDPVRQQSGNANTETLPSGWEQRKDPHGRTYYVDHNTRTTTWERPQPLPPGWERRVDDRRRVYYVDHNTRTTTWQRPTMESVRNFEQWQSQRNQLQGAMQQFNQRYLYSASMLAAENDPYGPLPPGWEKRVDSTDRVYFVNHNTKTTQWEDPRTQGLQNEEPLPEGWEIRYTREGVRYFVDHNTRTTTFKDPRNGKSSVTKGGPQIAYERGFRWKLAHFRYLCQSNALPSHVKINVSRQTLFEDSFQQIMALKPYDLRRRLYVIFRGEEGLDYGGLAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASTINPDHLSYFCFIGRFIAMALFHGKFIDTGFSLPFYKRMLSKKLTIKDLESIDTEFYNSLIWIRDNNIEECGLEMYFSVDMEILGKVTSHDLKLGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQWLQYFDEKELEVMLCGMQEVDLADWQRNTVYRHYTRNSKQIIWFWQFVKETDNEVRMRLLQFVTGTCRLPLGGFAELMGSNGPQKFCIEKVGKDTWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE
What is the function of this protein?
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.  Ubiquitinates ERBB4 isoforms JM-A CYT-1 and JM-B CYT-1, KLF2, KLF5 and TP63 and promotes their proteasomal degradation.  Ubiquitinates RNF11 without targeting it for degradation.  Ubiquitinates and promotes degradation of TGFBR1; the ubiquitination is enhanced by SMAD7.  Ubiquitinates SMAD6 and SMAD7.  Ubiquitinates and promotes degradation of SMAD2 in response to TGF-beta signaling, which requires interaction with TGIF.
What are the official names of this protein?
NEDD4-like E3 ubiquitin-protein ligase WWP1, Atrophin-1-interacting protein 5, AIP5, HECT-type E3 ubiquitin transferase WWP1, TGIF-interacting ubiquitin ligase 1, Tiul1, WW domain-containing protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein. Nucleus.
Protein: CAPZB_MESAU
Sequence: RLPPQQIEKSPWSNKYDPPLEDGAMPSARGCWDSIHVVEVQEKSGSGTMNLGGSLTRQMEKDETVSDCSPHIANIGRLVEDMENKIRSTLNEIYFGK
What is the function of this protein?
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends.  Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.  Plays a role in the regulation of cell morphology and cytoskeletal organization (By similarity).  Forms, with CAPZB, the barbed end of the fast growing ends of actin filaments in the dynactin complex and stabilizes dynactin structure.  The dynactin multiprotein complex activates the molecular motor dynein for ultra-processive transport along microtubules (By similarity).
What are the official names of this protein?
F-actin-capping protein subunit beta, CapZ beta.
What is the protein family that this protein belongs to?
Belongs to the F-actin-capping protein beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere.
Protein: ACSF_BRASO
Sequence: MIAMEGGSGNISTKMALEDTILTPRFYTTDFAAMDRLNVDLVRREWDAVMAELRADHNRKHFVRTPEFDKDLNELPEALRAEFKDFLVSSLTAEFSGCVLYAEIKKRITNPDIRELFQFMSRDEARHAGFINEILKDHGIGVDLGFLTKTKKYTYFKPKFIFYATYLSEKIGYARYITIYRQMERHPERQFHPIFKWFERWCNDEFRHGEAFALLMRADPKLLSGYNKLWIKFFLLAVFATMHVRDHMRPAFYEALGMPPDEYDMRVFRITSEISRQVFPVMLDIDNPRFWEGLKRLREISEAIAEAKAQGGIMGTLKRAVLPLKAALTFGRLYMLPAKNNELPREIRLQPAW
What is the function of this protein?
Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis.  Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME).
What are the official names of this protein?
Aerobic magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase, Aerobic Mg-protoporphyrin IX monomethyl ester oxidative cyclase.
What is the protein family that this protein belongs to?
Belongs to the AcsF family.
Protein: PVK2_EUBSB
Sequence: GSSGLISMPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-2, EubSp-PVK-2.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYC_ACIAD
Sequence: MQPFVLYNSEQRKKVEFVPRKPGHIDMYVCGMTVYDYCHIGHARVMVAFDYIIRFLRSQGWDVRYIRNITDIDDKIIKRANENNETIQQLTSRFIDAMNEDAAKLGCAEPDEAPKATEYIGEMQNMISTLVDKGSAYPASNGDVYFEVSKFEKYGRLSGRKLEDMQAGASERVDIEVEKKHPFDFVLWKGAKPNEPSWVSPWGNGRPGWHIECSAMSTCCLGNHFDIHGGGSDLTFPHHENEIAQSEASTGEQYVNYWMHVGFINVDGEKMSKSLGNFFTIRDVMEKFHPEVIRYFIVSSHYRSPVNFSDVALKEAKTALTRFYHAFKAYEQVYGQNDSTQKDEQFIERFNIAMRDDFNTPEAIAVLFELNRELNRAVKEQQAEQAAIYYVTLRHLTQILGLVQHDVDEFLKSDIGQEVLSLSDDEIQAMIQQRADAKKAKDFSGADAIRQALLDQGVVLEDTRQGTLWRRAD
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.