PharMolix/UniProtQA huggingface dataset:
Protein: ACSA_BRUA2
Sequence: MSEKLYPVLPEAKKNTLIDNETYLEWYEESVSDPDGFWAKHGRRIDWFKPFTKVKNTDFNGDVTIKWYEDGVTNVSYNCIDRHLKSRGDKVAIIWEGDNPYIDKKITYRELYENVCRMANVLKKHGVKKGDRVTIYLPMIPEAAYAMLACARIGAVHSVVFAGFSPEALAGRIVDCESTFVITADEGVRGGKPVALKENTDTAIDIAAKQYVMVNKVLVVRRTGGKVSWGRGRDLWYHQEVASVEPHCEPEPMNAEDPLFILYTSGSTGKPKGVLHTTGGYLVYASMTHQYVFDYHDGEIYWCTADVGWVTGHSYIVYGPLANGATTLMFEGVPNFPDQGRFWEVVDKHHVNIFYTAPTALRALMGAGDEFVTRSSRSTLRLLGSVGEPINPEAWEWYYNVVGDQKCPIVDTWWQTENGGILITPLPGATDLKPGSATRPFFGVKPVLVDNEGNVQEGVADGNLCISDSWPGQMRTVYGDHKRFIETYFSTYKGMYFSGDGCRRDEDGYYWITGRVDDVLNISGHRLGTAEIESALVSHHSVSEAAVVGYPHPIKGQGIYCYVTLMTGADAQDPDELRKELVQHVRKEIGPIATPDKIQFAPGLPKTRSGKIMRRILRKIAEDEFGALGDTSTLADPGVVDDLIENRQNKK
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: Y1916_ACIB5
Sequence: MHCDIYRSSKKDEMYIYIARPNYPDETEQADPFEKVPEAVLQAFGRATFVMHLELAPTRKLARVNVLHVLDSLQTKGFFIQMPPEGLINPNAVEPEGLRGA
What are the official names of this protein?
YcgL domain-containing protein AB57_1916.
Protein: CH601_PROM1
Sequence: MAKLLSFSDESRGALEKGVNNLANALKVTIGPKGRNVVIEKKFGAPDIVNDGVTIAKEIDLEDPFENIGAKLIEQVASKTKEKAGDGTTTATVLAQFMVQEGLRNTAAGASPIELRRGMEKAVAQIVDDLKKKSKSVSGDAIKQVATVSAGGDEEIGSMIADAIDKVSFDGVITVEESKSLATELDITEGMAFDRGYSSPYFVTDEDRLICEFENPSILITDKKISSIADLIPVLETVQKNGTPLIILAEEVEGEALATLVVNKNRGVLQVAAVRAPSFGERRKAALGDIAVLTGGTLISEDKAMSLEKVQISDLGQARRVTITKDSTTIVANDNQNTELSNRIASIKRELDETDSEYDQEKLNERIAKLAGGVAVIKVGAPTETELKNRKLRIEDALNATRAAIEEGIVAGGGTTLLELSEGLGDLAKKLEGDQKTGVEIIKRALTAPTKQIAINAGFNGDVVVSDIKRLGKGFNAQTGEYVDLLEAGILDASKVIRLALQDAVSIASLLITTEVVIADKPEPPSAPGAEGGDPMGGMGGMGGMGGMGGMGGMGGMGMPGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 1, 60 kDa chaperonin 1, Chaperonin-60 1, Cpn60 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KITH_STRA1
Sequence: MAQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRDEFGVVSSRIGMRREAVPISDDMDIFSYIQNLPQKPYCVLIDECQFLSKKNVYDLARVVDDLDVPVMAFGLKNDFQNNLFEGSKHLLLLADKIDEIKTICQYCSKKATMVLRTENGKPVYEGDQIQIGGNETYIPVCRKHYFNPDI
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_VESOH
Sequence: MSINIQEIIKEYQSKIGDTGSTNVQVALLTARIRHLTKHFKTHKKDHHSRRGLLHLVSQRKKLLTYLRGNNKTAYSKLISHLELRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: RL32_VIBPA
Sequence: MAVQKNRKTRSKRGMRRSHDALTTAALSVDATSGETHLRHNVTAEGYYRGQKVINK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: YIDD_YERPP
Sequence: MASPLSPGSRILIGLIRGYQLVISPLLGPRCRFHPTCSHYGIEALRRFGMIKGSWLTLKRVLKCHPLNSGGDDPVPPKLDDNREH
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y1146_STRMK
Sequence: MLLHIPDILSADQVADFRRRLDAADWTDGRETVGHLGAQAKHNQQLPEGSPLRRELGEIILVALARHPLFFSAALPLKYLPPRFNRYSGGGTYGFHVDGAVMNLANGEQLRSDISCTLFLSAPYEYEGGELIISDTYGEHEVKLPAGDLIVYPSSSLHQVRPVTAGARVASFFWVQSMVRDDVQRRLLWEMDGSIERLRQTGGDAEAVLQLTGVYHNLLRRWSEV
What are the official names of this protein?
PKHD-type hydroxylase Smlt1146.
Protein: HOBOT_DROME
Sequence: MAPYIMIVEFLCLWSSVSAVNCPFFVFYDAITSLLGFSIIWKPKEKVTIMAEAADFVKNKINNGTYSVANKHKGKSVIWSILCDILKEDETVLDGWLFCRQCQKVLKFLHKNTSNLSRHKCCLTLRRPTELKIVSENDKKVAIEKCTQWVVQDCRPFSAVTGAGFKNLVKFFLQIGAIYGEQVDVDDLLPDPTTLSRKAKSDAEEKRSLISSEIKKAVDSGRASATVDMWTDQYVQRNFLGITFHYEKEFKLCDMILGLKSMNFQKSTAENILMKIKGLFSEFNVENIDNVKFVTDRGANIKKALEGNTRLNCSSHLLSNVLEKSFNEANELKKIVKSCKKIVKYCKKSNLQHTLETTLKSACPTRWNSNYKMMKSILDNWRSVDKILGEADIHVDFNKSSLKVVVDILGDFERIFKKLQTSSSPSICFVLPSISKILELCEPNILDLSAAALLKERILENIRKIWMANLSIWHKAAFFLYPPAAHLQEEDILEIKVFCISQIQVPISYTLSLESTETPRTPETPETPETPETPETPETPETPETPETPESLESPNLFPKKNKTISSENEFFFPKPVTESNSNFNESPLDEIERYIRQRVPLSQNFEVIEWWKNNANLYPQLSKLALKLLSIPASSAELKECFP
What is the function of this protein?
Essential for hobo transposase activity.
What are the official names of this protein?
Transposable element Hobo transposase.
What are the subcellular locations of this protein?
Nucleus.
Protein: MNME_POLNA
Sequence: MLARHHHPIVAIATAPGRGGVGIVRLSGQRIAPVVQALCGRKLSPRQATYLPFRDAHGQIIDKGLAIFFPAPHSYTGEDVLELQAHGGPVVLQLLLARCLEAGAALDPATGQPVLAQLRVAEPGEFTERAFLNDKIDLAQAEAIADLIDASTETAARSAARSMSGEFSQAVNTLLEQLIHLRMLVEATLDFPEEDIDFLQQADAQGQLLRLQATLASVLARATQGAILREGIKVVIAGQPNVGKSSLLNALAGAELAIVTPVAGTTRDKVSQLIQIEGVPLHVVDTAGLREALDEVEKIGIQRAWTEIESADAVLFLHDLARHDATENPLYAINYIADDARLQSALALKLPKNTAIIDVWNKSDMAGPELLRQVNGGVLISAKTGAGLQALREQLLRVVGWQAAPEGVFMARERHVSALRSVQIQLLTAQNQLQAAVPALDLLAEDLRQAQLHLSSITGAFNADDLLGEIFSKFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRM5_HUMAN
Sequence: MVLWILWRPFGFSGRFLKLESHSITESKSLIPVAWTSLTQMLLEAPGIFLLGQRKRFSTMPETETHERETELFSPPSDVRGMTKLDRTAFKKTVNIPVLKVRKEIVSKLMRSLKRAALQRPGIRRVIEDPEDKESRLIMLDPYKIFTHDSFEKAELSVLEQLNVSPQISKYNLELTYEHFKSEEILRAVLPEGQDVTSGFSRIGHIAHLNLRDHQLSFKHLIGQVMIDKNPGITSAVNKINNIDNMYRNFQMEVLSGEQNMMTKVRENNYTYEFDFSKVYWNPRLSTEHSRITELLKPGDVLFDVFAGVGPFAIPVAKKNCTVFANDLNPESHKWLLYNCKLNKVDQKVKVFNLDGKDFLQGPVKEELMQLLGLSKERKPSVHVVMNLPAKAIEFLSAFKWLLDGQPCSSEFLPIVHCYSFSKDANPAEDVRQRAGAVLGISLEACSSVHLVRNVAPNKEMLCITFQIPASVLYKNQTRNPENHEDPPLKRQRTAEAFSDEKTQIVSNT
What is the function of this protein?
Involved in mitochondrial tRNA methylation (PubMed:26189817).  Specifically methylates the N1 position of guanosine-37 in various tRNAs.  Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside.  This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.
What are the official names of this protein?
tRNA (guanine(37)-N1)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase, tRNA methyltransferase 5 homolog.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Nucleus. Cytoplasm. Note=Predominantly in the mitochondria and in the nucleus.
Protein: ESP1_ARATH
Sequence: MASSGDDLRLLSLIDVGDNVFSSFSDYLKPFSTLSTSRKKQDRATTIRALAKQFLPFLNKSISLLPKRLSVANSDKEARESALDLFRAYELCLDCLELVSAQLACKPHTVQSQRLRMIHCLDVWGLYENVYTEAFKVLEKLRGSDSKSRKSRLLPEVQDGDAEMALVVVDAVAAIFRAVAMSQQLDDKRYRKVLLLLEEVGGWLRVLDAKVYEKLHRAMVTSMGKCAVSLVREAERFNGDLVISFCDLTVKEHYKSALSKDRVYKFAREVLSVLFGFKDRKMSVTIDISMSVLRSLSCQFEDESNENLMEFFDLVDYCAHKFRAAGDMYCAKVSKKLNEMAAIFVEAIPQLNLVLRLYSTGLSITVCNSKLGEIKLEDSTDDWKIQAMFDDDARWQSLVSLLGMVDSYSGDEGNQTGSSSIGGHRNYNNKTHDSCKDRNKITCWPQYVDALKFLCQPLADFIYSVKRKIVLETEMSCASAHLITIHDAFLQFCDGCLFLQRCTSDKGDREIANNKAFLNAAMGAFIVSLRTQLKLEISAHLVEDVIGSPWIQSQELKYLIATLYNIGIVLYRNKELNKACEALKLCSKVSWRCVELHCHMFVNQSSSSDNDLSEDAIMDFVGEACNRCAFYLDILQKCSRRKIRQNIVHILENWLSAEHLIRRLPGPEAIVKQWVKIERECHTDLDAAGSCTTLYSLLSSSQKKSKRGIGKILEQELLAYDRVLPLRSNLGQQTRIKIADILLKDVYVTEDMHIERARILIWKARMTRTSGTEHITECICFLSEAISILGELHHGPNEEGSPSSHMLPIAYCLRAFCTQEADPNSKKVFQDISTSLNLWLRILSLDDSGDSLPTENIIPLLYNMIDLMSVKGCTELHHHIYQLIFRLFKWKNVKLEVCLAMLWECRRLSHALCPSPISDAFIQTLSENCADKSTCIDFWMDCLKDSKAKLIGFQQNFHDLHNKDEGPFQSDITIDDIKDAASELISSASLSGNSSFAAAYLYYDLCERLISFGKLSEALSYAKEAYRIRTLIFQDKFKYTAEKHIEKHNEDGKISEIRTFSIKNFQVYRLLATDFWPCGNFLWDINRCYLSPWSVLQCYLESTLQVGILNELIGNGLEAETILSWGKAFSCSQSLFPFVVAFSSALGNLYHKKQCLDLAEKELQNAKEILIANQRDFSCVKCKLKLEVTLDKQLGDISRKQIDRVSQTDGFLHAESLFSAALGKFCCSAWKSCIRSHGEEIAEEIVIDRNGGEGLGHNSSKTKLSIKEPPGNRGSRRGGRANKTCLSKDQDLISEPTSRLTRSMRHSLREQCQNRSNVPEVVSKKPNLCDRSVGSRGERVLLDTSNALPGFCICYKEKRQQCLSEEVTESGSLNNLVSLKWELCHRKLASSILVSLGKCLGDSGRIHLAHEALLHSISVLFKSTWSSHNQPSVSQLLEFIGKEVTRDVFAVDRAIILYNLCWLNLRNYHCRKSRSICCDLFHIPFTKLVSWLMLAFVLSGEVPILFQKVSRLLASLYLLSSSNSEFTFESDGNELSASHWVSFFHQASLGTHLSYHFISNLSQKHKSQCLSDKECTEATCSSCMVPEDLDLPRLAPDRTQDLVQFAKEFFINLPSSTIICISLLGGALNQLLQELMHIRSPVCAWVLISRLNPESQPVATLLPVDSIVEDMSDDSANLSSTEATQVKSLKGPWLCPWGTTVVDEVAPAFKSILEESHSSSSTTEEDTIESRGLWWKKRKKLNHRLGIFLRNLEASWLGPWRCLLLGEWSNYKLPDSAQKKLVNDLKSKCKMEVNEMLLKVILGGGTDNFKGEACVAQLSLRNGCYVGRGGYLYEEDSCKTPTAASNISESRHELALKLIHDAASKLGQQDGHENREPIILVLDPEVQMLPWENIPILRKQEVYRMPSVGCISAVLKKRSLQGEPAKSHVASFPLIDPLDSFYLLNPGGDLTDTQVTFESWFRDQNFEGKAGSEPSAIELTEALETHDLFLYFGHGSGAQYIPRREIEKLDNCSATFLMGCSSGSLWLKGCYIPQGVPLSYLLGGSPAIVATLWDVTDRDIDRFGKALLEAWLQERSDSSSEGGCSQCESLANDLAAMTLKGTKRSRKPSSRNKPAQSDVDGSGKIECNHKHRRKIGSFIAAARDACNLQYLIGAAPVCYGVPTGITRKKGIDALLPSSSR
What is the function of this protein?
Cleaves SYN1, releasing sister chromatid cohesion.  Required for the release of cohesin at anaphase I and anaphase II, whereas the release of cohesin during diplotene and diakinesis occurs in a separase-independent process.  Essential for embryo and endosperm development.  May play a role in centromeric heterochromatin structure/formation during early meiosis, non-homologous centromere association and radial microtubule system (RMS) formation.  May regulate the mitosis-specific cyclin CYCB1-1.
What are the official names of this protein?
Separase, Protein EXTRA SPINDLE POLES, AtESP, Protein RADIALLY SWOLLEN 4.
Protein: T23O_XANCB
Sequence: MPVDKNLRDLEPGIHTDLEGRLTYGGYLRLDQLLSAQQPLSEPAHHDEMLFIIQHQTSELWLKLLAHELRAAIVHLQRDEVWQCRKVLARSKQVLRQLTEQWSVLETLTPSEYMGFRDVLGPSSGFQSLQYRYIEFLLGNKNPQMLQVFAYDPAGQARLREVLEAPSLYEEFLRYLARFGHAIPQQYQARDWTAAHVADDTLRPVFERIYENTDRYWREYSLCEDLVDVETQFQLWRFRHMRTVMRVIGFKRGTGGSSGVGFLQQALALTFFPELFDVRTSVGVDNRPPQGSADAGKR
What is the function of this protein?
Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine.  Catalyzes the oxidative cleavage of the indole moiety.
What are the official names of this protein?
Tryptophan 2,3-dioxygenase, TDO, Tryptamin 2,3-dioxygenase, Tryptophan oxygenase, TO, TRPO, Tryptophan pyrrolase, Tryptophanase.
What is the protein family that this protein belongs to?
Belongs to the tryptophan 2,3-dioxygenase family.
Protein: MUTS_SHEPC
Sequence: MNVIDTDDLEKHTPMMRQYLTMKAEHHDMLLFYRMGDFYELFYDDAKRASELLGISLTARGKSGGDPIPMAGIPYHAVEGYLAKLVQIGQSVAICEQIGDPATAKGPVERKVVRIVTPGTLTDEALLQERQDNLLAAVYQGKVGFGYATLDVSSGRFVIAELDTKESLEAELQRTNPVEILYSEDFGELGLLSHFKGKRRRPEWEFDYDTSIKLLLAQFGTKDLHGFGISDARLSLQAAGCLMQYVKDTQRTTLPHINAIIRFNQADSIVLDAATRRNLELTQNLAGGRDNTLAAVLDNTATAMGSRMLQRWIHQPLRDPNQIIARQTAVNELLKTGTHEPLHEQLKALGDIERIMARLALRTARPRDFARLRQALSLLPELQQSLSVLNAPHTVKLCQYLGEFPEEQALLERAIVDNPPMLIRDGGVIREGYNNELDEWRGLSEGASDYLVQLEAREKERTGINTLKVGYNRVHGYYIEVSRLQSSQVPLNYQRRQTLKNMERYITPELKEYEEKVLSSQGKALALEKQLWEQLFDLILPKLHELQAFARAAAELDVLSNFAERAETLGYICPQLSQDIGVQIDAGRHPVVERVSQTPFIANPVTLHNQRRMLIVTGPNMGGKSTYMRQVALITLMAHIGCFVPAERAVIGPIDRIFTRIGASDDLASGRSTFMVEMTETANILHNATAQSLVLMDEIGRGTSTYDGLSLAWSAAEYLAQQIGAMTLFATHYFELTQLPDLMAGVYNVHLDAIEHEDTIAFMHAVQEGAASKSYGLQVAALAGVPAKVIKAAKHKLQQLESRDHQLEGTKTPIQTLLALPEPAENPALTKLQAINPDNLTPKQALDLLYELKRLS
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: GLO2_ACTSZ
Sequence: MLKPISALNDNYIWVYGRENCPVIVVDITEIEPLLPFLRENKFAVEAVLLTHKHDDHVGGVAAFKRYFPDVPVYGPQECADKGATRIVNEGEIVTANYRIRVIPTGGHTAQHVSYVTDGCLFCGDTLFSAGCGRVFTGNYGQMYDSVQRLKTLPDDTLVCPAHEYTLANLAFAESVMKDKSAVKNQRVLVEKKRAENRPSVPTTLGLEKQINPFLIAENPAQFETWRKAKDQF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: NQRF_PSEAB
Sequence: MIGFEIFLAIGMFTAIVLGLVAIILVARAKLVSSGDVTIQINGEHSLTVPAGGKLLQTLATNNVFLSSACGGGGTCAQCKCVVVEGGGEMLPTEESHFTRRQAKEGWRLSCQTPVKQDMQIRVPEEVFGVKKWECTVESNPNVATFIKELTLRLPDGESVDFRAGGYVQLECPPHVVEYKDFDIQPEYRGDWDKFNMWRYVSKVDETVIRAYSMANYPEEQGVVKFNIRIASPPPGSDLPPGQMSSWVFNLKPGDKVTVYGPFGEFFAKDTEAEMVFIGGGAGMAPMRSHIFDQLRRLKSNRKISFWYGARSLREAFYTEEYDQLQAENPNFQWHLALSDPQPEDNWTGLTGFIHNVLFENYLKDHPAPEDCEFYMCGPPMMNAAVIKMLTDLGVERENILLDDFGG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit F, Na(+)-NQR subunit F, Na(+)-translocating NQR subunit F, NQR complex subunit F, NQR-1 subunit F.
What is the protein family that this protein belongs to?
Belongs to the NqrF family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RL10_STRA1
Sequence: MSEAIIAKKAEQVELIAEKMKAAASIVVVDSRGLTVEQDTNLRRSLRESDVEFKVIKNSILIRAAEKAGLEDLKELFVGPSAVAFSNEDVIAPAKVISDFAKDAEALEIKGGSVDGKFTSVEEINALAKLPNKEGMLSMLLSVLQAPVRNVAYAVKAVAEKDEEVA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: K22E_MOUSE
Sequence: MSCQISCRSRRGGGGGGGGGFRGFSSGSAVVSGGSRRSNTSFSCISRHGGGRGGSGGGGFGSQSLVGLGGYKSISSSVAGNSGGYGGSSFGGSSGFGGGRGFGGGQGFGGSGGFGGGSGFGGGQGFGGGSRFGGGSGFGGGGFGGGSFGGGRFGGGPGGFGGPGGFPGGGIHEVSVNQSLLQPLDVKVDPEIQNVKSQEREQIKTLNNKFASFIDKVRFLEQQNQVLRTKWELLQQLDVGSRTTNLDPIFQAYIGMLKKQVDRLSAERTSQESELNNMQDLVEDFKKKYEDEINKRTSAENDFVTIKKDVDSCYMDKTELQARLDILAQEVNFLRTLYDAELSQLQQDVTDTNVILSMDNNRNLDLDSIIAEVQNQYEMIAHKSKAESEELYHSKYEELQVTAVKHGDSLKEIKMEISELNRTIQRLQGEISHVKKQCKGVQDSIADAEQRGEHAIKDARGKLTDLEEALQQCREDLARLLRDYQELMNTKLSLDVEIATYRKLLEGEECRMSGDFSDNVSVSITSSTISSSVASKTGFGSGGQSSGGRGSYGGRGGGGGGGSTYGSGGRSSGSRGSGSGSGGGGYSSGGGSRGGSGGGYGSGGGSRGGSGGGYGSGGGSGSGGGYSSGGGSRGGSGGGGVSSGGGSRGGSSSGGGSRGGSSSGGGGYSSGGGSRGGSSSGGAGSSSEKGGSGSGEGCGSGVTFSFR
What is the function of this protein?
Probably contributes to terminal cornification (By similarity).  Associated with keratinocyte activation, proliferation and keratinization (By similarity).  Required for maintenance of corneocytes and keratin filaments in suprabasal keratinocytes in the epidermis of the ear, potentially via moderation of expression and localization of keratins and their partner proteins (PubMed:24751727).  Plays a role in the establishment of the epidermal barrier on plantar skin (PubMed:26603179).
What are the official names of this protein?
Keratin, type II cytoskeletal 2 epidermal, Cytokeratin-2e, CK-2e, Epithelial keratin-2e, Keratin-2 epidermis, Keratin-2e, K2e, Type-II keratin Kb2.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CMOB_NAUPA
Sequence: MDINKVLKERQKWFEWKNIKPIYEKIVQWQIENKQLNVKNVKLNDIIEITLDENKEKLKEIEQIAKMLKPWRKGPFKINDLFIDTEWRSFIKWNIIKPHINLENKDVLDVGCNNGYYMFRMLEMNPKSITGFDPSALFNLQFEFINNFIKSDIEYKLLGVEHIPFYDKKFDTIFCLGVLYHRPDPITMLKELKAGLNPGGEVILDTLIIEGDEEIALCPVRYQKMKNVYFIPTLKALYNWIEKAKFKDVKFIGKRYTDLEEQRKTDWIEGESLNNFLNEDLTKTVEGYPPPLRVYLKLKN
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: LPXD_HAEDU
Sequence: MAVFRLSELAEQIGATLKGNADLAITSIAALNNAEPTHITFISNAKYRSQLSQSKAGAIIVTAEDVEFCQATQNLLIVKDPYLAYALLAQYMDDLPKSANEISESAVISATAKLGKNVSIGANVVIESGVELADDITIGAGCFIGKNTKIGARSHLWANISVYHNVEIGSDCLIQSSAVIGSDGFGYANDKGRWIKIPQTGGVIIGNRVEIGACTCIDRGALDPTIIEDNVIIDNLCQIAHNVHIGFGTAIAGGVILAGSLKIGRFCQIGGASVINGHMEICDGAIITGMSMIMKPITEKGVYSSGIPAQTNKEWRKTAALTMNIADMNKRLKAIEKQLTE
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: VATE_CHLTR
Sequence: MADLSAQDKLKQICDALREETLKPAEEEAGSIVHNAREQAKRIVEEAKEEAQRIIRSAEETADQTLKKGEAALVQAGKRSLENLKQAVETKIFRESLGEWLDHVATDPEVSAKLVQALVQAVDAQGISGNLSAYIGKHVSARAVNEALGKEITSKLKEKGVSVGNFSGGAQLKVEERNWVLDMSSEVLLDLLTRFLQKDFREMIFQSC
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: HIS5_CORJK
Sequence: MNSSLSSRRPHVALLDYGSGNVRSAQRAVERAGAEVEVTRDPETVQRADGLLVPGVGAYSACMKQLHSVYGDRLIGQRLAGGRPVLGICVGMQILFDRGVEFAEGTGEAGAGEAAFTEGMGEWPGTVEKLDADVLPHMGWNTVEVGDGSSASALGKPAAEPTKMFAGIEETERFYFVHSYGVQEWELLTDGRTEPPLVHWASHGRSRFVAAVENGPLWATQFHPEKSGDAGLKLLQNWVDTL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_DINSH
Sequence: MARILITSAIPYINGIKHLGNLVGSQLPADLYARYARARGHEVMFICATDEHGTPAELAAAKAGKPVAEYCAEMHAVQSDIAKRFGLSFDHFGRSSSERNKALTQYFAGKLAENGLIEEVSEKQVYSHADGRFLPDRYIEGTCPNCGYDKARGDQCENCTKQLDPTDLIDPRSAISGSTDLEVRETKHLYLRQSALKDQLDAWIDSKTDWPILTTSIAKKWLHDGDGLQDRGITRDLDWGVPVKKGTEDWPGMEGKVFYVWFDAPIEYIAGTAEWADANGLDDAAWERWWRTDKGADEVRYVQFMGKDNVPFHTLSFPATIMGSGDPWKLVDYIKSFNYLTYDGGQFSTSQGRGVFMDQALEILPADYWRWWLLSHAPENSDSEFTWENFQASVNKDLADVLGNFASRVTKFCRSKYGEEVPAGGAYGPAEEALIAELTTKLRAYEGHMDAMEVRKAAAELRAIWVAGNEYLQAAAPWSVFKTDPDAAAAIIRLGLNLVRFYAVLSQPFIPDASAALLRAMKAEDAGWPGDVAEALAALPAGHAFAVPEVTFAKISDADREAWAEKFSGTRD
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN382_HUMAN
Sequence: MPLQGSVSFKDVTVDFTQEEWQQLDPAQKALYRDVMLENYCHFVSVGFHMAKPDMIRKLEQGEELWTQRIFPSYSYLEEDGKTEDVLVKFKEYQDRHSRPLIFINHKKLIKERSNIYGKTFTLGKNRISKTILCEYKPDGKVLKNISELVIRNISPIKEKFGDSTGWEKSLLNTKHEKIHPAVNLHKQTERVLSGKQELIQHQKVQAPEQPFDHNECEKSFLMKGMLFTHTRAHRGERTFEYNKDGIAFIEKSSLSVHPSNLMEKKPSAYNKYGKFLCRKPVFIMPQRPQTEEKPFHCPYCGNNFRRKSYLIEHQRIHTGEKPYVCNQCGKAFRQKTALTLHEKTHIEGKPFICIDCGKSFRQKATLTRHHKTHTGEKAYECPQCGSAFRKKSYLIDHQRTHTGEKPYQCNECGKAFIQKTTLTVHQRTHTGEKPYICNECGKSFCQKTTLTLHQRIHTGEKPYICNECGKSFRQKAILTVHHRIHTGEKSNGCPQCGKAFSRKSNLIRHQKTHTGEKPYECKQCGKFFSCKSNLIVHQKTHKVETTGIQ
What is the function of this protein?
Functions as a sequence-specific transcriptional repressor.
What are the official names of this protein?
Zinc finger protein 382, KRAB/zinc finger suppressor protein 1, KS1, Multiple zinc finger and krueppel-associated box protein KS1.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PLSY_NEIG2
Sequence: MFNIPAVAVSYLIGSLSFAVIVSKYYGMDDPRTYGSGNPGATNVLRSGKKKAAALTLLGDAAKGLVAVLLARVLQEPLGLSDSAIAAVALAALVGHMWPVFFGFKGGKGVATALGVLLALSPATALVCALIWLVMAFGFKVSSLAALVATTAAPLAALFFMPHTSWIFATLAIAILVLLRHKSNILNLIKGKESKIGEKR
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RRP36_PYRTR
Sequence: MVLANKLDRNLRAAEESSDGEDYYEVTDRSSSASVIEADEGGNVISSDDDMSDASDHDDDKIKAQMSKVSFGALAKAQDALSSKQSVDRKRKRGDDTSKSQEDKLEALRERLRQIKAEKLANGTQPSKKAKKSKTKTKTTQDDNVEEKEDSDSDAAPHARSSKHAPAVQSSKRMVSRKRNVVEVKKPVFRDPRFDNVSGPRPEDYVVEKRYSFLKDYRASEIAELRNTIKKTKNEGEKEQLKKKLLSMESQQKARENKERLQDVTREHKKKEKELVKEGKKPFFLKKSEQKKIALVDRFQNMKAKQRDKVIERRRKKVTAKERKNMPDERRTA
What is the function of this protein?
Component of the 90S pre-ribosome involved in the maturation of rRNAs.  Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity).
What are the official names of this protein?
rRNA biogenesis protein RRP36, Ribosomal RNA-processing protein 36.
What is the protein family that this protein belongs to?
Belongs to the RRP36 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.