PharMolix/UniProtQA huggingface dataset:
Protein: PLSX_LEPBL
Sequence: MWIAVDVMSGDYGPEKIIEGAVNAVNQDGANVVLVGKEEEVGEILLKFEYDTSRVRNQHASEIIDMNDSPSIAVRALRDSSVVQATQLVADKTCVGMFSPGNTGATMASALLYLGRIPGVLRPPIAAPIPQENGPPMLLLDAGANVDCKPDYLAQFAVMGEIYSKLIFNISNPKIGILSNGEEDKKGNAVSLKAFEMIKKLPVCFVGNVEGRDLYGGGKDVDVVVCDGFIGNIVLKATEGLSKSIFNVLRESIKQSSLAQTGALLLKPTFGAIKKRLDYAEYGGALLLGVDGICLIGHGSSNALSVQRAVRVVTECAQRQINDRIAADIKKYDI
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: MURA_CORGL
Sequence: MKDKFLVTGGAQLQGAVKVYGAKNSVLKLMAAALLAEGTTTLTNCPEILDVPLMRDVLVGLGCDVTIDGSTVTITTPAELSSNADFPAVTQFRASVCVLGPLTARCGRAVVSLPGGDAIGSRPLDMHQSGLEKLGATTRISHGAVVAEAEKLVGANITLDFPSVGATENILTASVMAEGRTVLDNAAREPEIVDLCRMLRSMGANIEGEGSPTITIEGVEKLTPTQHEVIGDRIVAGTWAYAAAMTRGDITVGGIAPRYLHLPLEKLKIAGAKVETYENGFRVQMDKQPEATDYQTLPFPGFPTDLQPMAIGINAVSNGTSVITENVFESRFRFVDEMLRLGADANVDGHHVVIRGIEQLSSTSVWSSDIRAGAGLVLAALCADGVTEVHDVFHIDRGYPNFVENLQKLGATIERVSS
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXK_ELUMP
Sequence: MDLEKTRDNLKNNVFGRFFLYVLSKGYELGTIVNKFLYENGWRKSYSVNTRVVCVGNITAGGTGKTTAVLLAARTLAEAGIRTAIISRGYKRDKKNKNPVVLFDDELENNWVTAGDEPFMMSRALADVKVPIVIHEDRHLAATEALKRFKSQVLLLDDGFQHFRLKRDANIVLIDARNPFGGGQLLPYGTLREGLSGLKRANLVLLTHSNQADQRKKEDIKDQIRLQNEDIEILEAVHQPEHYFDICNSVKVPLNHLKGEAGVFSAIGEPGGFEDTLKDLGLKLVKVWRYPDHRRYTEEDLKTFVDLAGENPLVTTFKDFVKFPENWRDILKKNVYVLSVSMKIKGKKEFDIFAEALYPKFTNLNVKKESKSRK
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: DEOD2_VIBPA
Sequence: MATPHINAQPGDFAETVLMPGDPLRAKYIAETFLEDVKQVCDVRNMFGFTGTYKGKKVSVMGHGMGIPSCCIYVHELIAEYGVKNVIRVGSCGAVRDDVNLMDVVIGMGASTDSKVNRIRFNNHDFAAIADFSLLEEAVKQARAQEVPVKVGNVFSADLFYTPEADIFEKMEKLGILGVDMEAAGIYGVAADLGAKALTILTVSDHIIRGEKLSSEERQKSFNDMMKVALETAINI
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type 2, PNP 2.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: MMM1_MAGO7
Sequence: MTPDSCPVRPEPTLSFTQGLIVGQISVVFLIAAFIKFFIFGDPPSAEETASLRASERRSRTLAHKKSLLSLRTSNQRPGSQQQQSVLNRKKSSILRSGPPSLTIGSILNKTYYRVESHQPESLDWFNVLVAQTIAQFRSDAQHDDAILTSLTKALNGTSRPSFLDEIRVTELSLGEDFPIFSNCRIIPVDEDGLDFGPGKAFDANMATRDGGTLQARMDVDLSDMITLALETKLLLNYPKKLTAVLPVALAVSVVRFSGTLAISFIPSNPSQSTPTKMVFNFLDDYRLDFSIRSLVGSRSRLQDVPKIAQLVESRLHRWFDERCVEPRFQEIPLPSMWPRKKNARGGDDAIADVERSMSKAKGADVARDLRREVLVEAEARQAAQRDSLRYRRPRADDAFPMPGSLAVDD
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Maintenance of mitochondrial morphology protein 1.
What is the protein family that this protein belongs to?
Belongs to the MMM1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: IF3_GEOSL
Sequence: MAKPTVNINQAIRAREVRVVGADSEQLGIMSLQEALALAEARQLDLVEVSPTAVPPVCRIMDYGKFKYQQSKKLQEARKKQSHVQVKEVKLRPKTDEHDLMTKIKHVRRFIEEGNKAKVTLVFRGREITHLEFGSRALDRVAAELEDIAVVEFKPKMEGRSMFMIVAPKVKK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRB_AGARV
Sequence: MEFKLHSKYKPTGDQPQAIEQLVKGFKEGNQFETLLGVTGSGKTFTMANVIAALNKPTLIISHNKTLAGQLYGEMKEFFPENAVEYFVSYYDYYQPEAYVPQSDTYIAKDSSVNDEIDKLRLSATAALTERKDVIVVASVSCIYGLGSPDEWTGMSISLRPGQERDRDDLARALIDLQYTRNDMDFHRGTFRVHGDVLDIFPANADDTAIRVEFFGDEIDRIVEVDVLTGEVKCSLEHTMIFPASHYVVSQEKINEACLNIEKELDERVKYFKGEDKLIEAQRIAERTNFDIEMMRETGFCSGIENYTRHLNFAKPGEPPMTLIDFFPDDFLIIVDESHITIPQIGGMYAGDRSRKTTLVDYGFRLPSALDNRPLNFEEFEGKIDQMLFVSATPNKYENEHELLRAEQIIRPTGLLDPEISVRPVEGQIDDLVSEVNKETANHHKVLITTLTKRMAEDLTNYMAELGIRVKYLHSDIDTLERAEIIRDLRLDVFDVLVGINLLREGLDIPEITLVAILDADKEGFLRSETSLIQTIGRAARNSEGHVIMYADKITDSMRVAIDETKRRRKVQEEYNEAHGITPQTIQKSVRDLIAISKKVAADENALDKDPESMSKKELEKHIADIEKKMKKAAAELNFEAAAEYRDKLIMLKNTLRDIR
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_COREF
Sequence: MANPKNEAALAELKAQFAETDSIVLTEYRGLTVAQTTELRRALGDDVQYSVAKNTLVKIAAQEAGVEGLDDLLTGPTAVAFIKGEAVDTAKVLKKFGDDNKAFVVKGGYMDGNALTADQVKAIAELDNRETTLAKLAGAMKGNLAKAAGLFNAPASQVARLAAALQEKKDA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: ILVC_NITSB
Sequence: MALPIYYDKDCDINLIKSKKVAIIGFGSQGHAHAENLRDSGVEVKIGLYPGGRSWKKAEAKGFDVLEVADASEWADVVMILIPDEIQSEVYYRDIEPNLKESDTIAFGHGFNIHYGRIKPRADINVMMVAPKAPGHTVRSEFVKGGGIPDLIAVAQDPSGNTLELAKSYASAIGGGRTGIIHTTFKDETETDLFGEQAVLCGGVSALIQAGFETLTEAGYPEEMAYFECLHELKLIVDLIYEGGLANMRYSISNTAEYGDYVSGPRVINEASRQAMKDILKEIQNGKFAKDFILEGMAGYPRMTAERRNCEAHPIEQVGKRLRAMMPWITANKIVDQEKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: RL25_BDEBA
Sequence: MKTRIDLTVEPRETGKHNSRGLRTSRNVPAVIYGAVTPTNVSVGEKEIVKYNTRAYENALFNLKSSDKTANGIVVLIKSVDVHPLTRRPQHVDFFALDLKKAVRVNVEVRLEGKAIGLSEGGLLNVVLRSVEVECLPTEIPEFFTADISNLAVGDALHVSDIKVSGSVKMITGAEQTIAVVNAQEEEVAAAPAAAAAPAAAAPAAKAPAAKK
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: NIFA_AZOBR
Sequence: MPGAMRQSTSNLELLTIYEVSKILGSSLDLQQTLREVLRALAYQLQMHRGRVYLVGEDNVLRLVAANGLSNEAAAQIEFRDGEGITGRILKTGMPAVVPNLAEEPLFLNRTGGREDLDEQVASLVGVPIKAAGVVVGVLTIDRISDEGPQGHFGSDVRFLTMVANLIGQTVRLHRTVAEERRFMMRETFRMQKELRPVAAPINDVVCTSPNMLEVMAQVHRVAPFKSTVLIRGESGTGKELIARAIHNMSPRKDAPFIRVNCAALPESLLESELFGHEKGAFTGAQKDHKGRFELASGGTLFLDEIGDISPNFQAKLLRVLQEQEFERVGGSKTIKTDVRLICATNLNLEEAVGHGKFRADLYFRINVVTIHLPPLRERRQDIGPLARHFVAKFAKDNGMALVMEDEALEVLNRCTWPGNVRELENCIERAATQSRDGIIRTESLSCSLNLCNSSVLFQYRTLGASVGGLAPSMGPGAINRVPPGRPGGPAAANAPKTPAMPAPVPEPAGAAAARGRPARRVVPRPLAGLRRRPAGGSGPPDPACPCPSRAPLPPQAPPPSPAAAPPPAAEVPLDEPESGSLRDRLLWAMERTGWVQAKAARLLGMTTRQVSYALRKYNIEIKRF
What is the function of this protein?
Required for activation of most nif operons, which are directly involved in nitrogen fixation.
What are the official names of this protein?
Nif-specific regulatory protein.
Protein: PPIA1_RHIO9
Sequence: MSNPKVFFDVSANSKPLGRIVMELRADVVPQTAENFRALCTGEKGFGYKGCSFHRVIPEFMLQGGDFTNHNGTGGKSIYGNKFRDENFTLKHTGPGDLSMANAGPNTNGSQFFITTIKCSWLDGKHVVFGRVTEGMDVVQNIESLGSPNGTPRAKIIIDNCGQL
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase A1, PPIase A1, Cyclophilin A1, Cyclosporin A-binding protein, Rotamase A1.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TNNC2_CHICK
Sequence: MASMTDQQAEARAFLSEEMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELANCFRIFDKNADGFIDIEELGEILRATGEHVTEEDIEDLMKDSDKNNDGRIDFDEFLKMMEGVQ
What is the function of this protein?
Troponin is the central regulatory protein of striated muscle contraction.  Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C.  The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments.
What are the official names of this protein?
Troponin C, skeletal muscle.
What is the protein family that this protein belongs to?
Belongs to the troponin C family.
Protein: YL324_MIMIV
Sequence: MDYIVSPTSSEPYEFYRDRTFRGGANGNQTNMDTSPEDITDSDEQNDTTTTTSEMSSTSSVPSIGENKVSKNNKSAGISKISDSKLIFDSDNKDQDDEDDEDDEELEGLDTEGGFVLSNSDITTSDLYNLQMRIFRSETETDDDTDSETTENVRRALNNINSRKNIFDTEDRKILNMNSTEKWTRKTIKKNNKYH
What are the official names of this protein?
Uncharacterized protein L324.
Protein: FUMC_XYLFT
Sequence: MEMQMSNSDRYRIEHDSMGDLRVPIDALWGAQTQRAIENFPISGRSMPQGFIHALGFIKAAAAKVNAELGLLPKSMAKEIEAAALDVAAGRYDAEFPVDIYQTGSGTSSNMNANEVIATLAMRATKGPIHPNDHVNLGQSSNDVVPTAIRISATLAVQGRLLPALKHLRKMINKRARGLGSVVKTGRTHLMDAMPLTFAQEFGAWSAQIVSAEARLNDTLKRLHRLPLGGTAIGTGINTDPHFGRNAVKVLSALTGIHFESANNKFEGLAAQDDLVELSGQFNTLAVALMKIANDLRWMNAGPLAGLGEIELPALQPGSSIMPGKVNPVIPEAVVMVASQVIGHHTAVTVAGQSGNFQLNVTLPLIAYNLLESATLLGNVVMLLADKVIVGLKVRQDRVQEVLERNPILVTALNPIIGYEKAAVIAKRAYKEHRPVLEVACEESNLNPVELARLLDPAALTEGGIHVVGGGGG
What is the function of this protein?
Involved in the TCA cycle.  Catalyzes the stereospecific interconversion of fumarate to L-malate.
What are the official names of this protein?
Fumarate hydratase class II, Fumarase C, Aerobic fumarase, Iron-independent fumarase.
What is the protein family that this protein belongs to?
Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVC_NEIMF
Sequence: MQVYYDKDADLSLIKGKTVAIIGYGSQGHAHAANLKDSGVNVVIGLRQGSSWKKAEAAGHVVKTVAEATKEADVVMLLLPDETMPAVYHAEVTANLKEGATLAFAHGFNVHYNQIVPRADLDVIMVAPKGPGHTVRSEYKRGGGVPSLIAVYQDNSGKAKDIALSYAAANGGTKGGVIETTFREETETDLFGEQAVLCGGVVELIKAGFETLTEAGYAPEMAYFECLHEMKLIVDLIFEGGIANMNYSISNNAEYGEYVTGPEVVNASSKEAMRNALKRIQTGEYAKMFIQEGNVNYASMTARRRLNADHQVEKVGAQLRAMMPWITANKLVDQDKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: GLTB_SPIOL
Sequence: MALQSAPKLLYSSPSPSVFSANERRVAFSDFVGLSKKRSRRRRIAGTFRNFPALSAVSSAIKAVVDVDRAHHSTDSGSPTVSTSSHPLDQQVVNLEDILAERGACGVGFIANLDNKGSFQIVKDALTALGCMEHRGGCGSDNDSGDGSGVMTAIPWDLFNDWGKDQGIGPFDRSHTGVGMVFLPKDDLLAEEAKKVVLDTFAQEGIEVIGWRSVPTNVSVVGRNAKETMPNIQQVFVRIIKEDSTDDIERELYICRKLIERAASSHTWASELYFCSLSNQTIIYKGMLRSEVLGMFYYDLQNERYTSPFAIYHRRYSTNTSPRWPLAQPMRFLGHNGEINTIQGNLNWMRSREPSIQSPVWRGRENEIRPYGNPKASDSANLDSAAELLIRSGRTPEEALMILVPEAYKNHPTLMIKYPEAVDFYDYYKGQMETWDGPALLLFSDGKTVGACLDRNGLRPARYWRTVDNVVYVASEVGVLPMDESKVTMKGRLGPGMMISVDLSSGQVYENTEVKKRVASSNPYGKWVKENLRSLKAVNFLSRALLENDTILRNQQAFGYSSEDVQMVIESMASQGKEPTFCMGDDIPLAVMSQKPHMLYDYFKQRFAQVTNPAIDPLREGLVMSLEVNIGKRGNILEVGPENASQVILPSPVLNEGELEALVNDPLLKAQMLPIFFDIRKGVEGTLEKRLNRLCEAADEAVRNGSQMLVLSDRSEELEPTRPAIPILLAVGAVHQHLIQNGLRMYTSIVVDTAQCFSTHQFACLIGYGASAICPYLALETCRQWRLSNKTVNLMRTGKIPTVTIEQAQKNFCKAVKSGLLKILSKMGISLLSSYCGAQIFEIYGLGKDVVDIAFQGSVSKMGGLTLDELARETLSFWVKAFSEDTAKRLENFGFIQFRPGGEYHVNNPEMSKLLHKAVRNKSESAYAVYQQHLANRPVSVLRDLLEFKSDRAPISVGKVEPATSIVERFCTGGMSLGAISRETHEAIAIAMNRLGGKSNSGEGGEDPIRWRPLTDVVDGYSSTLPHLKGLQNGDTATSAIKQVASGRFGVTPTFLVNADQIEIKIAQGAKPGEGGQLPGKKVSAYIARLRNSKPGVPLISPPPHHDIYSIEDLAQLIYDLHQINPKEKVSVKLVAEAGIGTVASGVAKGNADIIQVSGHDGGTGASPISSIKHAGGPWELGLSETHQTLISNGLRERVILRVDGGLKCGVDVMMAAAMGADEYGFGSLAMIATGCVMARICHTNNCPVGVASQREELRARFPGVPGDLVNFFLYVAEEVRGILAQLGFEKLDDIIGRTDILKPRDISLMKTQHLDLSYILASAGLPTMSSTAIRKQEVHTNGPVLDDQILSDPEIIDAIENEKIVNKTVKIFNVDRAVCGRIAGVIAKKYGDTGFAGQLNLTFEGSAGQSFAVFLTPGMNIRLVGESNDYVGKGMAGGELIVTPAENPGFRPEDATIVGNTCLYGATGGQIFVRGKAGERFAVRNSLAEAVVEGTGDHCCEYMTGGCVVILGKVGRNVAAGMTGGLAYILDEDDTLIPKVNKEIVKIQRVTAPVGQMQLKNLIEAHVEKTGSSKGASILKDWDKYLPLFWQLVPPSEEDTPEASAMFEQMTSEGASLQSA
What is the function of this protein?
Catalyzes the reductive conversion of 2-oxoglutarate plus glutamine to two molecules of glutamate, using reduced ferredoxin as the electron donor (PubMed:9507092).  Contains one FMN but no FAD (PubMed:8651698).  The FMN-binding domain is also involved in the delivery of sulfite to the reaction center of SQD1 (PubMed:15752726).
What are the official names of this protein?
Ferredoxin-dependent glutamate synthase, chloroplastic, Fd-GOGAT, SoFdGOGAT.
What is the protein family that this protein belongs to?
Belongs to the glutamate synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: PRMA_AERHH
Sequence: MPWIQIRINATAKTADKVSNMLLGRGAQAVTFMDAKDVPVYEPMPGETPLWGETEVMGLFDAETDPAPTIAFFQQIFGEDVGYKVEQLEDKDWVREWMDHFHPMQFGERLWICPSWRDVPNPDAVNVMLDPGLAFGTGTHPTTALCLQWLDGLDLAGKTVVDFGCGSGILGIAALKLGAARVIGIDIDPQAIQASRDNAERNGVADQIELYLPADQPQDVEADVVVANILAGPLRELAPLIAGHGKAGSLMALSGVLESQAPELETIYGQWFEMDPTAVKEEWCRLSGRKLG
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA2G5_MOUSE
Sequence: MKGLLTLAWFLACSVPAVPGGLLELKSMIEKVTGKNAFKNYGFYGCYCGWGGRGTPKDGTDWCCQMHDRCYGQLEEKDCAIRTQSYDYRYTNGLVICEHDSFCPMRLCACDRKLVYCLRRNLWTYNPLYQYYPNFLC
What is the function of this protein?
Secretory calcium-dependent phospholipase A2 that primarily targets extracellular phospholipids.  Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity), preferentially releasing fatty acyl groups with a low degree of unsaturation such as oleoyl (C18:1) and linoleoyl (C18:2) groups (PubMed:14962950).  Hydrolyzes low-density lipoprotein (LDL) phospholipids releasing unsaturated fatty acids that drive macrophage polarization toward an M2 phenotype (PubMed:14962950, PubMed:24910243).  May act in an autocrine and paracrine manner.  Contributes to lipid remodeling of cellular membranes at different subcellular locations and generation of lipid mediators involved in pathogen clearance.  Cleaves sn-2 fatty acyl chains of cardiolipin, a major component of the inner membrane of mitochondria and bacterial membranes (By similarity).  Promotes phagocytosis of bacteria in macrophages through production of lysophosphatidylethanolamines (By similarity).  Displays bactericidal activity against Gram-positive bacteria by directly hydrolyzing the phospholipids of the bacterial membrane (PubMed:11694541, PubMed:16407308).  Promotes phagocytosis and killing of ingested fungi likely through controlling phagosome-lysosome fusion and phagosome maturation (PubMed:19342668).  Plays a role in biosynthesis of cysteinyl leukotrienes (CysLTs) in myeloid cells (By similarity).  In eosinophils, triggers perinuclear arachidonate release and LTC4 synthesis in a PLA2G4A-independent way (By similarity).  In neutrophils, amplifies CysLTs biosynthesis initiated by PLA2G4A (By similarity).  Promotes immune complex clearance in macrophages via stimulating synthesis of CysLTs, which act through CYSLTR1 to trigger phagocytosis (PubMed:20432503).  May regulate antigen processing in antigen-presenting cells (PubMed:20817863).  In pulmonary macrophages regulates IL33 production required for activation of group 2 innate lymphoid cells (PubMed:29346348).  May play a role in the biosynthesis of N-acyl ethanolamines that regulate energy metabolism.  Hydrolyzes N-acyl phosphatidylethanolamines to N-acyl lysophosphatidylethanolamines, which are further cleaved by a lysophospholipase D to release N-acyl ethanolamines (By similarity).
What are the official names of this protein?
Phospholipase A2 group V, PLA2-10, Phosphatidylcholine 2-acylhydrolase 5.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family.
What are the subcellular locations of this protein?
Secreted. Cell membrane. Cytoplasmic vesicle, phagosome. Recycling endosome. Golgi apparatus, cis-Golgi network. Golgi apparatus, trans-Golgi network.
Protein: RS3A_HALLT
Sequence: MSERSVSKSREQKRWYSVLAPEQFDRQELGETLAEEPDQVVGRTITTTLGELTGDSGANNTKLTFKITDVGSDTAYTEFIKYELTRDYLRSLVRRGASKVEASITVLTTDDYRIRVQPVALTTKKADRSQEKAIRRVMIDKVHAAAEDRTFESFVDAIVEGNLSSAIYGDAKLIYPLRRVEIQKLTLEARPSEVAAEEETAVDVDADEVAVDADE
What are the official names of this protein?
30S ribosomal protein S3Ae, Ribosomal protein S1e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
Protein: GATA_PARPJ
Sequence: MHEKSLTELRAALTAKECSAVELAQLYLKRIDAANSLNAFIQVDPDLTLAQAKAADALLHTGHAGPLVGLPIAHKDVFVTKGWRSTAGSKMLSNYESPFDATVVARLQNAGMVCVGKTNMDEFAMGSSNENSYFGPVQNPWDVKAVPGGSSGGSAAAVAARLAPAATGTDTGGSIRQPASFSGITGIKPTYGRVSRYGMIAFASSLDQGGPMAQSAADCATLLNAMAGFDERDSTSLVRDDEDYTRYLGKPWKEESAAKPLAGLRIGLPKEYFGAGLADDVRASVDAALKQYEALGATLVDVSLPKTELSIPVYYVIAPAEASSNLSRFDGVRFGHRAAEYRDLLDMYKKSRAEGFGPEVKRRILVGAYVLSHGYYDAYYLQAQKIRRIIAQDFQEAFKQCDVIMGPVAPSVAWDLGAKGDDPVQMYLADIYTLSVSLAGLPGMSVPCGFGAGANAQRPVGLQIIGNYFNEARMLQVADAFQRATDWHRKAPAGV
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: GSA1_LISW6
Sequence: MLNYSKSEKAFKEAKKVLPGGVNSPVRAFNSVDATPVFMDHGKGAYITDIDGNEYIDYVLSWGPLILGHANPSVVDAITKAAMKGTSFGTPTEIETELAKLVIERVPSIEIVRMVSSGTEATMSAIRLARGYTKREKILKFEGSYHGHGDSLLIKAGSGVATLGLPDSPGVTKGLAADTITVPYNDVEGAKLAFEKYGEEIAAVIVEPVAGNMGVVPPIEGFLEGLRDLTTKYGALLIFDEVMTGFRVDYYSAQGYYVVTPDITCLGKVIGGGLPVGAYGGKKEIMEQIAPAGSIYQAGTLSGNPLAMNAGFETVRQLTPQHYDVFRSLIKRMEEGLTEISTRREVPISINKAGSMFGFFFTDQKVINFDTAKTSNLEFFRNYYREMLNQGIFLPPSQFEGVFISTMHTEKEIDKTLEAFDHTCKTLRG
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase 1, GSA 1, Glutamate-1-semialdehyde aminotransferase 1, GSA-AT 1.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMU_LEGPA
Sequence: MNLQIIILAAGQGKRMYSDTPKVLHHLAGKPLLTHVVETAQQLNPDAIHVIYGHGGEQIKSSLPNLPVHWVHQAEQLGTGHAVLQAMPHIPDDAYVLVLSADVPLIQVGTLQSLIECSQRQNPDHSVLALLVAELENPSGLGRIIRNNQGEIYSIVEEKDANEQVKNIKEIYSGVCCTLANNLKKWLPQLSNSNAQGEYYLTEIISLAVQNKTPITSLTAKNSFEVQGINNRQQLQQLERTWQQRAANQLMEKGATLADANRFDLRGELYCGKDVYIDINCIFTGKVVLGNGCKIGPNCSLTNVTLGDGCEVYANSVLEGCHIANDCHIGPFARLRSGTQLASHCKIGNFVETKKAIFDEGTKASHLSYLGDVLLGKNVNVGAGTITCNYDGVNKHQTIIEDGVFIGSDTQLVAPVTVGANATIGAGSTIRRNVPPDELTLTESRQKTIYGWKRPVKRERD
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.