PharMolix/UniProtQA huggingface dataset:
Protein: TRPV4_HUMAN
Sequence: MADSSEGPRAGPGEVAELPGDESGTPGGEAFPLSSLANLFEGEDGSLSPSPADASRPAGPGDGRPNLRMKFQGAFRKGVPNPIDLLESTLYESSVVPGPKKAPMDSLFDYGTYRHHSSDNKRWRKKIIEKQPQSPKAPAPQPPPILKVFNRPILFDIVSRGSTADLDGLLPFLLTHKKRLTDEEFREPSTGKTCLPKALLNLSNGRNDTIPVLLDIAERTGNMREFINSPFRDIYYRGQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHIVNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLLKCARLFPDSNLEAVLNNDGLSPLMMAAKTGKIGIFQHIIRREVTDEDTRHLSRKFKDWAYGPVYSSLYDLSSLDTCGEEASVLEILVYNSKIENRHEMLAVEPINELLRDKWRKFGAVSFYINVVSYLCAMVIFTLTAYYQPLEGTPPYPYRTTVDYLRLAGEVITLFTGVLFFFTNIKDLFMKKCPGVNSLFIDGSFQLLYFIYSVLVIVSAALYLAGIEAYLAVMVFALVLGWMNALYFTRGLKLTGTYSIMIQKILFKDLFRFLLVYLLFMIGYASALVSLLNPCANMKVCNEDQTNCTVPTYPSCRDSETFSTFLLDLFKLTIGMGDLEMLSSTKYPVVFIILLVTYIILTFVLLLNMLIALMGETVGQVSKESKHIWKLQWATTILDIERSFPVFLRKAFRSGEMVTVGKSSDGTPDRRWCFRVDEVNWSHWNQNLGIINEDPGKNETYQYYGFSHTVGRLRRDRWSSVVPRVVELNKNSNPDEVVVPLDSMGNPRCDGHQQGYPRKWRTDDAPL
What is the function of this protein?
(Microbial infection) Facilitates Zika virus (ZIKV) replication, possibly through its action on DDX3X.
What are the official names of this protein?
Transient receptor potential cation channel subfamily V member 4, TrpV4, Osm-9-like TRP channel 4, OTRPC4, Transient receptor potential protein 12, TRP12, Vanilloid receptor-like channel 2, Vanilloid receptor-like protein 2, VRL-2, Vanilloid receptor-related osmotically-activated channel, VR-OAC.
What is the protein family that this protein belongs to?
Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV4 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane. Apical cell membrane; Multi-pass membrane protein. Cell junction, adherens junction. Cell projection, cilium. Note=Assembly of the putative homotetramer occurs primarily in the endoplasmic reticulum. SUBCELLULAR LOCATION: [Isoform 1]: Cell membrane. SUBCELLULAR LOCATION: [Isoform 5]: Cell membrane. SUBCELLULAR LOCATION: [Isoform 2]: Endoplasmic reticulum. SUBCELLULAR LOCATION: [Isoform 4]: Endoplasmic reticulum. SUBCELLULAR LOCATION: [Isoform 6]: Endoplasmic reticulum.
Protein: DTX14_ARATH
Sequence: MDSAEKGLLVVSDREEVNKKDGFLRETKKLSYIAGPMIAVNSSMYVLQVISIMMVGHLGELFLSSTAIAVSFCSVTGFSVVFGLASALETLCGQANGAKQYEKLGVHTYTGIVSLFLVCIPLSLLWTYIGDILSLIGQDAMVAQEAGKFATWLIPALFGYATLQPLVRFFQAQSLILPLVMSSVSSLCIHIVLCWSLVFKFGLGSLGAAIAIGVSYWLNVTVLGLYMTFSSSCSKSRATISMSLFEGMGEFFRFGIPSASMICLEWWSFEFLVLLSGILPNPKLEASVLSVCLSTQSSLYQIPESLGAAASTRVANELGAGNPKQARMAVYTAMVITGVESIMVGAIVFGARNVFGYLFSSETEVVDYVKSMAPLLSLSVIFDALHAALSGVARGSGRQDIGAYVNLAAYYLFGIPTAILLAFGFKMRGRGLWIGITVGSCVQAVLLGLIVILTNWKKQARKARERVMGDEYEEKESEEEHEYIS
What are the official names of this protein?
Protein DETOXIFICATION 14, AtDTX14, Multidrug and toxic compound extrusion protein 14, MATE protein 14.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HEM62_NOSS1
Sequence: MGRHSDNSLQESANHTVLLTSPTNTIPKDSRQRSQQFMQNLQDEICTALEQLDGKASFHQDHWERAEGGEGRTRVIREGRVFEQGGVNFSAVWGNSLPASILAQRPEAAGHEFFATGTSMVLHPRNPYVPTVHLNYRYFEAGPIWWFGGGADLTPYYAFKEDAVHFHQTLKNACDVHNPEYYPTFKRWCDEYFYLRHREEQRGIGGIFFDYQDASGKLYVESQTDSSVAIYSQKVGNVARNWEDIFAFVQSCGQAFLPAYLPIVERRQGIEYGDRQRNFQLYRRGRYVEFNLVYDRGTVFGLQTKGRTESILMSLPPLARWEYCYEPEAGSPEAELTEVFLQPRDWV
What is the function of this protein?
Key enzyme in heme biosynthesis.  Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity).
What are the official names of this protein?
Coproporphyrinogen-III oxidase, aerobic 2, Coprogen oxidase 2, Coproporphyrinogenase 2.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDGC_CUPNH
Sequence: MWFKNLQVHRFSAPWSLSADEVEASLAKHAFFPGTSLEMQTQGWASPRDNGQLVHTVGGQMLLTLRTEKKLLPTTVVNQVTRARAAEIEEQQGYKPGRKQMKELKEQVTEELLPRAFSIRRDTRVWIDPDNGWLAIDAAATAKADEVRGMLFKALDPLPLINLHVNQSPVAAMTEWLAGDAAPGGFTVDQEIELQSGAESKATVRYVRHPLDPEDLRRHIAAGKRCTRLAMTWNDRVSFVLTDGLVVKKVAPLDVIKEQADGTAHDEDERFDADFTMMAGELSGMLGDLTEALGGERKA
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: SAFA_SHIDS
Sequence: MHATTVKNKITQRDNYKGIMSVIVVVLLLTLTLIAIFSAIDQLGISEMGRIARDLTHFIINSLQD
What is the function of this protein?
Connects the signal transduction between the two-component systems EvgS/EvgA and PhoQ/PhoP, by directly interacting with PhoQ and thus activating the PhoQ/PhoP system, in response to acid stress conditions.
What are the official names of this protein?
Two-component-system connector protein SafA.
What is the protein family that this protein belongs to?
Belongs to the SafA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: BEGIN_RAT
Sequence: MWTGGRRPGRLRRAASAADMEKLSALQEQKGELRKRLSYTTHKLEKLETEFDSTRHYLEIELRRAQEELDKVTEKLRRIQSNYMALQRINQELEDKLYRMGQHYEEEKRAMSHEIVALNSHLLEAKVTIDKLSEDNELYRKDCNLAAQLLQCSQTYGRVHKVSELPSDFQQRVSLHMEKHGCSLPSPLCHPSYADSVPTCVIAKVLEKPDPGSLSSRMSDASARDLAYRDGVENPGPRPPYKGDIYCSDTALYCPDERDHDRRPSVDTPVTDVGFLRAQNSTDSLAEEEEAEAAAFPEAYRREAFQGYAASLPTSSSYSSFSATSEEKEHAQASTLTASQQAIYLNSREELFSRKPPSATYGSSPRYAKAAATLGSPLEAQVAPGFARTVSPYPAEPYRYPASQQALMPPNLWSLRAKPSGNRLAAREDIRGQWRPLSVEDVGAYSYQAGAAGRAASPCNFSERFYGGGGGGGSPGKNAEGRASPLYASYKADSFSEGDDLSQGHLAEPCFLRAGGDLSLSPSRSADPLPGYATSDGDGDRLGVQLCGPGSSPEPEHGSRDSLEPSSMEASPEMHPPTRLSPQQAFPRTGGSGLSRKDSLTKAQLYGTLLN
What is the function of this protein?
May sustain the structure of the postsynaptic density (PSD).
What are the official names of this protein?
Brain-enriched guanylate kinase-associated protein.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: RAX2_HUMAN
Sequence: MFLSPGEGPATEGGGLGPGEEAPKKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLPEVRVQVWFQNRRAKWRRQERLESGSGAVAAPRLPEAPALPFARPPAMSLPLEPWLGPGPPAVPGLPRLLGPGPGLQASFGPHAFAPTFADGFALEEASLRLLAKEHAQALDRAWPPA
What is the function of this protein?
May be involved in modulating the expression of photoreceptor specific genes.  Binds to the Ret-1 and Bat-1 element within the rhodopsin promoter.
What are the official names of this protein?
Retina and anterior neural fold homeobox protein 2, Q50-type retinal homeobox protein, Retina and anterior neural fold homeobox-like protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y3710_CLOAB
Sequence: MKISNSKTSLEFERNKDFFQVRLESTQFKEAVLKELSDKVIVNEDNETWVLSYPVPEAAKSLASATRLAKTRLERLKLAQKLATLSGLENQFKIPFLHPENILLMGETLFVVHFGLHKLLAPFDMTPVDFLKSYKALIFYIFNSKVPFESLVSGSLAMNDKFSQTINSFESTQEIAEFIDEELQKETEKINRNIAFVSKGRYRFFKYFGTLAIILALVLGWFTYYYYSNSQKQNAIITAQTDFLTNNYDKTQTDLQNYSPSKLPKSARYILAVSSVNLSDLTTTQKQAILNNISTKSDDNTLNYWVYSGRGDFKQALNLAQNLGDVQLTLLAYTNLYETTKLNTTMDGAKKQQLLDEYNKKIQELTKNLGK
What are the official names of this protein?
Uncharacterized protein CA_C3710.
Protein: RL2_THIDA
Sequence: MALIKVKPTSAGRRAVVKVVTPGLHKGKPLAALLEPKKRGSGRNNNGHITVRHKGGGHKQHYRVVDFRRNKDGIPAKVERIEYDPNRSAHLALLCYADGERRYIIAPRGIAVGAQLVNGVEAPIKAGNCLPLRSIPVGSTVHCVEMMPGKGAQIARSAGTSVQLLAREGSYAQLRLRSGEIRKVHVDCRATLGECGNEEHSLRSIGKAGASRWRGIRPTVRGVVMNPVDHPHGGGEGRTAAGRHPVSPWGTPTKGYRTRSNKRTSNMIVRRRHAR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: MURJ_CHLTR
Sequence: MRKDDEGSLVRSLFNLLSGTFFSRLTGMLREIVMATYFGADPLVASFWLAFRTIFFLRKLLGGPILGLAFIPHFEFLRAQNISRATFFFRSFSRFFCYSAILFTLIIELGLCVWCSCVTGSLFDTLLLTIILLPSGIFLMMYTVNSTLLHCEKKFFSVGLAPSVVNVSWIGTVFLARNYDPRNRIFGLAVVLVIGFILEWAVTLPGVMKFLGQSKEVPQERDSIRALIAPLSLGLLSMGIFQLNLLCDMWLARYINEVGPLYLMYSVRIQQLPVHLFGLGVFTVLLPAISRCVQDQEHQQGYDLLRFSLKLTVAVMVVMTMGLLLFALPGVRVLYEHGVFPKTAVHAIVEVLRGYSGSIIPMALAPLVSALFYARRNYKVPMLVGIIAAVVNMVLNVIGCLVCKQVAVLAYATSLVSWGQLAMLWYCAGKSLPTYKGLMWRTFKESGKTVITTILAAVITIGVNIVTHTTYVVFIEPLTVPTKPLVSFLDQCGVFFAESALFLSVLFGLAKLLKTEDLMNLISFQYWKGHQSILRN
What is the function of this protein?
Involved in peptidoglycan biosynthesis.  Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
What are the official names of this protein?
Probable lipid II flippase MurJ.
What is the protein family that this protein belongs to?
Belongs to the MurJ/MviN family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YHFC_BACSU
Sequence: MVSQEAVVFLALSGAIAFLLPIGLIVWFKRKYGASLKVFFIGALTFFVFAQLLEGGVHVYVLQVNEMTKEAMQHPLWYGIYGCLMAGIFEECGRYLMMRFFMKRHHTWADGLAFGAGHGGLEAILITGLSSISLIVYAFAINSGTFEQLLVNGDVKQALLPIQEQLLHTPSYEWMLGGIERISAIAVQIGLSLLVLYAVKNRRPLFLLYSILLHALFNVPAVLYQRGIIEHAAAVEIIVALIAALSVYWIVKAKRVFQ
What are the official names of this protein?
Uncharacterized membrane protein YhfC.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSB9_ORYLA
Sequence: MLGEEAEPQWISEEVKTGTTIIAIEFNGGVVLGSDSRVSAGDSVVNRVMNKLSPLHDKIYCALSGSAADAQTIAEMVNYQLDVHSLEIDEDPQVRSAATLVKNISYKYKEELSAHLIVAGWDRRDGGQVFATLGGLLTRQPFAIGGSGSSYVYGFVDAEYRRGMTKEECQKFVVNTLALAMNRDGSSGGVAYIVTIDEHSTDEKVILGNDLPTFFDQ
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.  This subunit is involved in antigen processing to generate class I binding peptides (By similarity).
What are the official names of this protein?
Proteasome subunit beta type-9, Low molecular mass protein 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: HSLV_HAEI8
Sequence: MTTIVSVRRNGQVVVGGDGQVSLGNTVMKGNARKVRRLYNGKVLAGFAGGTADAFTLFELFERKLEMHQGHLLKSAVELAKDWRTDRALRKLEAMLIVADEKESLIITGIGDVVQPEEDQILAIGSGGNYALSAARALVENTELSAREIVEKSLKIAGDVCVFTNTNFTIEELPN
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_CARHZ
Sequence: MNRHTARELAFKALFGLDFAPEKTLDTLESLWAEKIAEGKIPPEKLVDFSRELVRGVIEKKERLDEIIRRRAIGWDFKRLAKVDKTLLRLALYEMLYRPDIDIPVSIDEAVELAKVYGEEESPKFINGILGYVAEHIDEFWEES
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: PPR39_ARATH
Sequence: MVRMMIRRLSSQASRFVQPRLLETGTLRIALINCPNELLFCCERGFSTFSDRNLSYRDKLSSGLVGIKADDAVDLFRDMIQSRPLPTVIDFNRLFSAIAKTKQYELVLALCKQMESKGIAHSIYTLSIMINCFCRCRKLSYAFSTMGKIMKLGYEPDTVIFNTLLNGLCLECRVSEALELVDRMVEMGHKPTLITLNTLVNGLCLNGKVSDAVVLIDRMVETGFQPNEVTYGPVLNVMCKSGQTALAMELLRKMEERNIKLDAVKYSIIIDGLCKDGSLDNAFNLFNEMEIKGFKADIITYNTLIGGFCNAGRWDDGAKLLRDMIKRKISPNVVTFSVLIDSFVKEGKLREADQLLKEMMQRGIAPNTITYNSLIDGFCKENRLEEAIQMVDLMISKGCDPDIMTFNILINGYCKANRIDDGLELFREMSLRGVIANTVTYNTLVQGFCQSGKLEVAKKLFQEMVSRRVRPDIVSYKILLDGLCDNGELEKALEIFGKIEKSKMELDIGIYMIIIHGMCNASKVDDAWDLFCSLPLKGVKLDARAYNIMISELCRKDSLSKADILFRKMTEEGHAPDELTYNILIRAHLGDDDATTAAELIEEMKSSGFPADVSTVKMVINMLSSGELDKSFLDMLSTTRASLK
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At1g12775, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ALLB_ECOUT
Sequence: MSFDLIIKNGTVILENEARVVDIAVKDGKIAAIGQDLGDAKDVMDASGLVVSPGMVDAHTHISEPGRSHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDRASIELKFDAAKGKLTIDAAQLGGLVSYNIDRLHELDEVGVVGFKCFVATCGDRGIDNDFRDVNDWQFFKGAQKLGELGQPVLVHCENALICDALGEEAKREGRVTAHDYVASRPVFTEVEAIRRVLYLAKVAGCRLHVCHVSSPEGVEEVTRARQEGQDVTCESCPHYFVLDTDQFEEIGTLAKCSPPIRDLENQKGMWEKLFNGEIDCLVSDHSPCPPEMKAGNIMKAWGGIAGLQSCMDVMFDEAVQKRGMSLPMFGKLMATNAADIFGLQQKGRIAPGKDADFVFIQPNSSYVLTNDDLEYRHKVSPYVGRTIGARITKTILRGDVIYDIEQGFPVAPKGQFILKHQQ
What is the function of this protein?
Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring.
What are the official names of this protein?
Allantoinase, Allantoin-utilizing enzyme.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.
Protein: SND1_DANRE
Sequence: MASAVPAQVQSSQASAPQLQRGIVKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGALARRAIQGQPDTKDTPDEPWAFQAREFMRKKVIGKEVCFTVENKTPQGREYGMVYLGKDTSGENIAESLVAEGLAMVRREGIRGNNPEQVRLCDLEDQAKSSKKGLWSEGGGSHTIRDLKYTIENPRNFVDSLHQKPVNAIIEHVRDGCMVRALLLPDYYLVTVMLSGIKSPTFKREADGSETPEPFAAEAKFFTESRLLQRDVQIILESCPNQVILGTILHPNGNITELLLKEGFARCVDWSMAVYTQGAEKLRAAERSAKERKVRIWKDYVAPTANLDQKDRQFVAKVMQVVNADAIVVKLNSGEYKTIHLSSIRPPRLEGEEKNKDKDKRFRPLYDIPYMFEAREFLRKKLIGKKVNVTVDYIRAATNAMEMGVPAFPERTCATVTIGGINIAEALVSKGLATVIRYRQDDDQRSSHYDELLAAEARAIKNGKGLHSKKEVPIHRVADISGETQKAKQFFPFLQRAGRSEAVVEYVFSGSRLKLYMPKETCLITFLLAGIECPRGSRNMPGGMQVAEPYSEEAMLFTKELVLQREVEVEVESMDIAGNFIDWLHIDGVNLSVALVENALSKVHFTAERSSYYKTLVSAEESARQRKEKLWANYEEKPNEEVAQVTEAKERGRNTDPSTSLEITDGLHFYAQDVETGTKLENLMESMRGEIAAQPPVEGSFAPRRGEFCIAKFADGEWYRARVEKVESPAKVHVFYIDYGNREVLSSTRLAALPPAFSTRTLPPQATEYAFAYIQVPQDEDARADAVDSVVRDIHNTQCLLNVEYSGMVCPQVTLQFADTKEDVGLGLVKEGMVMVDIRKEKYLQKMVTEYLNAQESAKSARLNIWR
What are the official names of this protein?
Staphylococcal nuclease domain-containing protein 1, 100 kDa coactivator, 4SNc-Tudor domain protein, p100 co-activator.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPA_BURMA
Sequence: MTDLTATPAPAEPAASAYDPTAKQKAQAKTARIPIKIVPIEKLKKPEWIRVKAATSSSRFNEIKTILREHNLHTVCEEASCPNIGECFGKGTATFMIMGDKCTRRCPFCDVGHGRPDPLDADEPKNLARTIAALKLKYVVITSVDRDDLRDGGAGHFVECIREVREQSPATRIEILTPDFRGRLDRALAILNAAPPDVMNHNLETVPRLYKEARPGSDYAHSLKLLKDFKALHPDVATKSGLMVGLGETTDEILQVMRDLRAHDVDMLTIGQYLQPSEHHLPVREYVHPDTFKMYEEEAYKMGFTHAAVGAMVRSSYHADLQAHGAGVV
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCBJ_ECO57
Sequence: MEQLRAELSHLLGEKLSRIECVNEKADTALWALYDSQGNPMPLMARSFSTPGKARQLAWKTTMLARSGTVRMPTIYGVMTHEEHPGPDVLLLERMRGVSVEAPARTPERWEQLKDQIVEALLAWHRQDSRGCVGAVDNTQENFWPSWYRQHVEVLWTTLNQFNNTGLTMQDKRILFRTRECLPALFEGFNDNCVLIHGNFCLRSMLKDSRSDQLLAMVGPGLMLWAPREYELFRLMDNSLAEDLLWSYLQRAPVAESFIWRRWLYVLWDEVAQLVNTGRFSRRNFDLASKSLLPWLA
What are the official names of this protein?
Uncharacterized protein YcbJ.
Protein: HHA_SALTY
Sequence: MSDKPLTKTDYLMRLRRCQTIDTLERVIEKNKYELSDNELAVFYSAADHRLAELTMNKLYDKIPSSVWKFIR
What is the function of this protein?
Interacts with H-NS and in this complex might contact DNA, which could provide an additional surface for DNA binding to the H-NS-Hha complex; may not bind DNA in the absence of H-NS (PubMed:23515315).  In vitro improves the ability of H-NS to bind DNA under a precise set of conditions (PubMed:23515315).
What are the official names of this protein?
Hemolysin expression-modulating protein Hha.
What is the protein family that this protein belongs to?
Belongs to the Hha/YmoA/Cnu family.
Protein: GHRB_YERP3
Sequence: MKPSIVLYKSIPTDLHQRLAQHFTVNSFDGLTPDNQPELLAALQQAEGLIGSGGKIDQDFLQLAPNLRAASTISVGYDNFDVEALSQRGIALMHTPTVLTETVADTMMALMLSTARRVVELAERVKAGEWQESIGDDWFGVDVHHKTIGILGMGRIGMALAQRAHFGFSMPVLYTSRRPHEAAEQRFGARHCSLDTLLAEADFLCITLPMTEQTYHMIGREQLAKMKSSAILINAGRGPVVDEQALIAALQDGTIHAAGLDVFEQEPLPVDSPLLTLRNVVAVPHIGSATHETRYNMAACAVDNLINALTGTVKENCVNPQVLITH
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
What are the official names of this protein?
Glyoxylate/hydroxypyruvate reductase B.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CENPQ_HUMAN
Sequence: MSGKANASKKNAQQLKRNPKRKKDNEEVVLSENKVRNTVKKNKNHLKDLSSEGQTKHTNLKHGKTAASKRKTWQPLSKSTRDHLQTMMESVIMTILSNSIKEKEEIQYHLNFLKKRLLQQCETLKVPPKKMEDLTNVSSLLNMERARDKANEEGLALLQEEIDKMVETTELMTGNIQSLKNKIQILASEVEEEEERVKQMHQINSSGVLSLPELSQKTLKAPTLQKEILALIPNQNALLKDLDILHNSSQMKSMSTFIEEAYKKLDAS
What is the function of this protein?
Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation.  May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex (PubMed:16622420).  Plays an important role in chromosome congression and in the recruitment of CENP-O complex (which comprises CENPO, CENPP, CENPQ and CENPU), CENPE and PLK1 to the kinetochores (PubMed:25395579).
What are the official names of this protein?
Centromere protein Q, CENP-Q.
What is the protein family that this protein belongs to?
Belongs to the CENP-Q/OKP1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Note=Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex.
Protein: MTB5_NEIGO
Sequence: MQQIKFIDLFSGMSGIRKGFEQACRKQSVACECVFTSEIKPAALEVLKQNYPDEVPYGDITKIETGDIPDFDILLAGFPCQAFSFAGKRLGFEDTRGTLFFDVARILKAKKPKGFILENVEGLVTHDRKDSTQKIGRTLTVILETLEALGYYVSWKVLNAKEFGIPQNRKRIYLTGSLKSKPDLSFETSPSPKLKNILESGLPTESSPFIKKLLKKFPPSELYGKSVKDKRGGKNNIHSWDIELKGAVTEEEKQLLNILLKERRKKNGLQKIGIDWMDGMPLTKAQISTFYKHPDLQNILDSLTDKGYLVLEHPKQKIGGQRIKDESLPKGYNIVSGKKSFEINKILDPNDVAPTLFAMDMEHLFVVDNGGLRTLTGKEGLRLFGYPDDYPFDIPKKDRCDLLGNTVAVPVIKAVSERLLHTL
What is the function of this protein?
A methylase, recognizes the double-stranded sequence 5'-GGNNCC-3', methylates C-5 on both strands, and protects the DNA from cleavage by the NgoBV endonuclease.
What are the official names of this protein?
Type II methyltransferase M.NgoBV, M.NgoBV, Cytosine-specific methyltransferase NgoV, M.NgoV, Modification methylase NgoBV.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
Protein: PYRH_RHIEC
Sequence: MSLEPVYKRVLLKASGEALMGAQGFGIDVTVADRIASDIAEARHMGVEVGVVVGGGNIFRGVAVASKGGDRVTGDHMGMLGTIINALALATSLRKLNIDTVVLSAISMPEICESFSQRATLYHLSMGRVVIFAGGTGNPFFTTDSAAALRAAEMGAQAIFKGTQVDGIYTADPKKYPDATRFDRLTHQEVLDRGLAVMDVAAVALARENSIPIIVFSIHEKGGFAEILTGGGLKTIVSDN
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_LEIXX
Sequence: MAAIEAVGAREILDSRGNPTVEVEVLLEDGTVSRAAVPSGASTGAFEAYELRDGDKGRYLGKGVEKAVDAVLDEIGPAIEGFEASDQRIVDEAMIELDGTDNKKRLGANAMLGVSLAVAKAAADSADLPLFRYLGGPNAHVLPVPMMNIINGGAHADTGVDIQEFMILPIGAETFSEGLRWGVETYHSLKALLKSKGLNTGLGDEGGFAPELEHNRAALDLIAEAIEKAGFTVGSQIALGLDVASTEFFENGVYRFEGQDRTAAEMSAYYTDLANNYPLVSIEDPLAEDDWEGWAHLNAEIGSTLQLVGDDLFVTNPKRLAQGIQQKAANSILVKVNQIGTLTETLDAVSLAQRSGMTAVLSHRSGETEDTTIADLAVATDSGQIKTGAPARSERVAKYNQLLRIEEELGEAAVYAGRSAFPRYQG
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: LIPS_BOVIN
Sequence: MDLRTMTQSLVTLAEDNMAFFSSQGPGETARRLTGVFAGIREQALGLEPALGRLLSVAHLFDLDTETPANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRTSHNLAELEAYLAALTQLRALAYYAQRLLTTNQPGRLFFEGDERVIADFLREYVTLHKGCFYGRCLGFQFTPAIRPFLQTISIGLVSFGEHYKRNETGISVTASSLFTDGRFAIDPELRGAEFERIIQNLDVHFWKAFWNITEIQVLSSLANMASTTVRVSRLLSLPPVAFEMPLTSDPELTVTISPPLAHTGPGPVLVRLISYDLREGQDSKELSSFVRSEGPRSLELRLRPQQAPRSRALVVHIHGGGFVAQTSKSHEPYLKSWAQELGAPILSIDYSLAPEAPFPRALEECFYAYCWAVKHCALLGSTGERICLAGDSAGGNLCFTVSLRAAAYGVRVPDGIMAAYPATMLQSTASPSRLLSLMDHLLPLSVLSKCVSTYAGAETEDHPDSDQKALGVMGLVQRDTALLLRDLRLGASSWLNSFLELGGQKSHLKSVSKTEPMRRSVSEAALTQPEGSLGTDSLKSLKLHDLGLRNSSDTTDTPELSLSAETLGPSAPSTINFLLGSEDGSEMSKAPEELNNKDRVRGVGAAFPEGFHPRRCSQGAMWMPLYSAPIVKNPSMSPLLAPDSMLQTLPPVHIVACALDPMLDDSVMFARRLRGLGQPVTLRVAEDLPHGFLSLAALCRETRQAAALCVERIRLILNLPGPPV
What is the function of this protein?
Lipase with broad substrate specificity, catalyzing the hydrolysis of triacylglycerols (TAGs), diacylglycerols (DAGs), monoacylglycerols (MAGs), cholesteryl esters and retinyl esters (By similarity).  Shows a preferential hydrolysis of DAGs over TAGs and MAGs (By similarity).  Preferentially hydrolyzes fatty acid (FA) esters at the sn-3 position of the glycerol backbone in DAGs and FA esters at the sn-1 and sn-2 positions of the glycerol backbone in TAGs (By similarity).  Catalyzes the hydrolysis of 2-arachidonoylglycerol, an endocannabinoid and of 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor (By similarity).  In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production (By similarity).
What are the official names of this protein?
Hormone-sensitive lipase, HSL, Monoacylglycerol lipase LIPE, Retinyl ester hydrolase, REH.
What is the protein family that this protein belongs to?
Belongs to the 'GDXG' lipolytic enzyme family.
What are the subcellular locations of this protein?
Cell membrane. Membrane, caveola. Cytoplasm, cytosol. Lipid droplet. Note=Found in the high-density caveolae. Translocates to the cytoplasm from the caveolae upon insulin stimulation. Phosphorylation by AMPK reduces its translocation towards the lipid droplets.