PharMolix/UniProtQA huggingface dataset:
Protein: SYC_BARBK
Sequence: MGNLRFYNTLTRKKEDFIPIDSSKVRLYVCGPTVYDYAHIGNARPVIVFDILFRLLRHVYGKDHVIYARNVTDVDDKINARAIREYPKLTLNDAIHQLTERTYDQFQQDTEALGCLLPTYQPRATDHLEEMRSLIERLLEKGHAYIAENHVLFSVNSIKNNPLYGVFAKRSLNEMKAGARVDVAPYKRDDMDFVLWKPSTQQEPGWKSPAGISVLGRPGWHIECSAMSMAKLLTPYGGGLACDDLSVNVFDIHGGGIDLIFPHHENEIAQSCSVFGTERMANFWMHNGFLQVEGRKMSKSFGNFITIRSILESNFVEFSNAMTDDLKQSWAGLSARFSMLQTHYREPLNWTAQRLAQSSSELYRWYELLRCERSCLDNGGVIDASLISTLSDDLNTPNSFTLLRKFYKEENAVALVQGMDLFGLLRQEWVREIECPLFVKGIDLDSKFIDQRIAERLLFIQNKEWAAADEIRNELAKKGIALKDEKDSQTGERITTWEVK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVC_SHEAM
Sequence: MAIILGVDPGSRITGYGVIQCQGRHQLYLGSGCIRTSSDELPDRLKQIFDGLQEIIRQYQPSQFAIERVFMAKNADSALKLGQARGAAIVAATVAGLPVAEYSATQIKNAVVGTGRAQKAQVQHMVQQMLKLPAAPQADAADALAVAMCHYHTHQSLVALGGRASVRTYGRYR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: DEPD7_PONAB
Sequence: MATVQEKAAALNLSALHSPAHRPPGFSVAQKPFGATYVWSSIINTLQTQVEVKKRRHRLKRHNDCFVGSEAVDVIFSHLIQNKYFGDVDIPRAKVVRVCQALMDYKVFEAVPTKVFGKDKKPTFEDSSCSLYRFTTIPNQDSQSGRVNKLYSPARYADALFKSSDIKSASLEDLWENLSLKPANSPHVNISATLSPQVINEVWQEETIGRLLQLVDLPLLDSLLKQQEAVPKVPQPKRQSTIVNSSNYLDRGILKAYSDSQEDEWLSAAIDCLEYLPDQMVVEISRSFPEQPDRTDLVKELLFDAIGRYYSSREPLLNHLSDVHNGIAELLVNGKTEIALEATQLLLKLLDFQNREEFRRLLYFMAVAANPSEFKLQKESDNRMIVKRIFSKAIVDNKNLSKGKTDLLVLFLMDHQKDVFKIPGTLHKIVSVKLMAIQNGRDPNRDAGYIYCQRIEQRDYSNNTEKTTKDELLNLLKTIDEDSKLSAKEKKKLLGQFYKCHPDIFIEHFGD
What are the official names of this protein?
DEP domain-containing protein 7.
What is the protein family that this protein belongs to?
Belongs to the DEPDC7 family.
Protein: RL16_CHLFF
Sequence: MLMPKRTKFRKQQKGQFAGLSKGATFIDFGEFGMQTLERGWVTSRQIEACRVAINRYLKRKGKVWIRVFPDKSVTKKPAETRMGKGKGAPDHWVAVVRPGRILFEVANVSKEDAQDALRRAAAKLGIRTRFVKRVERV
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: GDL66_ARATH
Sequence: MQRNRVLAFLLLAAQLLVKIPETCAKFPALIVFGDSTVDSGNNNQISTVLKSNFQPYGRDYFDGKATGRFSNGRIAPDFISEGLGLKNAVPAYLDPAYNIADFATGVCFASAGTGLDNATSAVLSVMPLWKEVEYYKEYQTRLRSYLGEEKANEIISESLYLISIGTNDFLENYYLLPRKLRKYSVNEYQYFLIGIAADFVTDIYRLGARKMSLSGLSPFGCLPLERTTQLFYGSKCIEEYNIVARDFNIKMEEKVFQLNRDLNGIQLVFSNPYDLVSEIIYHPEAFGFENVRSACCGTGYYEMSYLCDKMNPFTCSDASKYVFWDSFHPTEKTNAIVANHVLKYDLSRFQ
What are the official names of this protein?
GDSL esterase/lipase At4g26790, Extracellular lipase At4g26790.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family.
What are the subcellular locations of this protein?
Secreted.
Protein: CYB_ARCLU
Sequence: MTNIRKTHPLIKIINHSFIDLPTPSNISSWWNFGSLLGLCLIIQIMTGLFLSMHYTSDTTTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGMYYGSYTFMETWNIGVLLLFTIMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVIVHLLFLHETGSNNPTGLNSDADKIPFHPYYTIKDLLGVFILILSLMTLVLFFPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSILILALLPFLHTSKQRSLIFRPITQTLYWMLVANLLVLTWIGGQPVEHPFIIIGQLASISYFSIILILMPISGIIEDKLLKWSL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ATPE_STRPN
Sequence: MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAVLAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLRAERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: T2S1_STRFI
Sequence: MHQDYRELSLDELESVEKQTLRTIVQALQQYSKEAKSIFETTAADSSGEVIVLAEDITQYALEVAETYPINRRFAGFIDYKRVRWLPSPHGLLPQVLLVDAKASTEKNRDTLQRSQLPMDAEFRNTSSGEVVTMEAGVIPHLMLQSANDGVLPAVTTSIFVHFYYRELKDVEGRYRELKSIYVLSLPHARLKQRYNPDPDTSFFGAGKHSPARGEVARIRVYFDRLKEACPWRLQELHYSADSEYTQPRWRDLNDAGHEVTKEFLFLER
What is the function of this protein?
An F and P subtype restriction enzyme that recognizes the double-stranded sequence 5'-GGCCN(5)GGCC-3' and cleaves before N-9.
What are the official names of this protein?
Type II restriction enzyme SfiI, R.SfiI, Endonuclease SfiI, Type-2 restriction enzyme SfiI.
Protein: PLXA4_MOUSE
Sequence: MKAMPWNWTCLLSHLLVVGMGSSTLLPRQPPQLSQKPSFVTFRGEPAEGFNHLVVDERTGHIYLGAVNRIYKLSSDLKVLVTHQTGPDEDNPKCYPPRIVQTCNEPLASTNNVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFKLGEPFHKKEHYLSGVNESGSVFGVIVSYSNFDDKLFIATAVDGKPEYFPTISSRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTVIPDFDIYYVYGFSSGNFVYFLTLQPEMVSPPGSTTKEQVYTSKLVRLCKEDTAFNSYVEVPIGCERNGVEYRLLQAAYLSKAGAVLGRTLGVRPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQINDRIKDRLQSCYRGEGTLDLAWLKVKDIPCSSALLTIDDNFCGLDMNAPLGVSEMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKIRVDGPKGNALQYETVQVVDSGPVLRDMAFSKDHEQLYIMSERQLTRVPVESCGQYRSCGECLGSGDPHCGWCVLHNTCTRKERCERSREPRRFASEMKQCVRLTVHPNNISVSQYNVLLVLETYNVPELSAGVNCTFEDLSEMDGLVIGNQIQCYSPAAKEVPRIITENGDHHVVQLQLKSKETGMTFASTSFVFYNCSVHNSCLSCVESPYRCHWCKYRHVCTHDPNTCSFQEGRVKLPEDCPQLLRVDKILVPVEVIKPITLKAKNLPQPQSGQRGYECILNIQGIEQRVPALRFNSSSVQCQNTSYSYEGMEINNLPVELTVVWNGHFNIDNPAQNKVYLYKCGAMRESCGLCLKADPDFECGWCQSPGQCTLRQHCPAHESRWLELSGANSKCTNPRITEIIPVTGPREGGTKVTIRGENLGLEFRDIASHVKVAGVECSPLVDGYIPAEQIVCEMGEAKPSQHAGFVEICVAVCRPEFMARSSQLYYFMTLTLADLKPNRGPMSGGTQVTITGTNLNAGSNVVVMFGSQPCLFHRRSPSYIICNTTSSEEVLDMKVTVQVDRARIRQDLVFQYVEDPTIVRIEPEWSIVSGNTPIAVWGTHLDLIQNPQIRAKHGGKEHINICEVLNATEMTCQAPALALGPDHQSDLTERPEEFGFILDNVQSLLILNKTNFTYYPNPVFEAFSPSGILELKPGTPIILKGKNLIPPVAGGNVKLNYTVLVGEKPCTVTVSDVQLLCESPNLIGRHKVMARVGGMEYSPGMVYIAPDSPLSLPAIVSIAVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLESRVALECKEAFAELQTDIHELTSDLDGAGIPFLDYRTYTMRVLFPGIEDHPVLRDLEVPGYRQERVEKGLKLFAQLINNKVFLLSFIRTLESQRSFSMRDRGNVASLIMTVLQSKLEYATDVLKQLLADLIDKNLESKNHPKLLLRRTESVAEKMLTNWFTFLLYKFLKECAGEPLFSLFCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIEYKTLVLSCVSPDNVNSPEVPVKILNCDTITQVKEKILDAIFKNVPCSHRPKAADMDLEWRQGSGARMILQDEDITTKIENDWKRLNTVAHYQVPDGSVVALVSKQVTAYNAVNNSTVSRTSASKYENMIRYTGSPDSLRSRTPMITPDLESGVKLWHLVKNHEHGDQKEGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLDEQADKHGIHDPHVRHTWKSNCLPLRFWVNMIKNPQFVFDIHKNSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPSYKNWVERYYSDIGKMPAISDQDMNAYLAEQSRMHMNEFNTMSALSEIFSYVGKYSEEILGPLDHDDQCGKQKLAYKLEQVITLMSLDS
What is the function of this protein?
Coreceptor for SEMA3A.  Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton.  Plays a role in axon guidance in the developing nervous system.  Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin.  The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.
What are the official names of this protein?
Plexin-A4.
What is the protein family that this protein belongs to?
Belongs to the plexin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: UBIB_SALTY
Sequence: MTPGEVRRLYFIIRTFLSYGLDELIPRMRLTLPLRLWRYSLFWMPNRHKDKLLGERLRLALQELGPVWIKFGQMLSTRRDLFPPQIADQLALLQDKVAPFDGRLAKAQIEEAMGGLPVEAWFDDFDIQPLASASIAQVHTARLKSNGKEVVIKVIRPDILPVIQADLKLIYRLARWVPRLLPDGRRLRPTEVVREYEKTLIDELNLLRESANAIQLRRNFENSPMLYIPEVYSDYCSQNMMVMERIYGIPVSDVAALEKNGTNMKLLAERGVKVFFTQVFRDSFFHADMHPGNIFVSHEHPENPQYIGIDCGIVGSLNKEDKRYLAENFIAFFNRDYRKVAELHVDSGWVPPDTNVEDFEFAIRTVCEPIFEKPLAEISFGHVLLNLFNTARRFNMEVQPQLVLLQKTLLYVEGVGRQLYPQLDLWKTAKPFLESWIKDQVGIPALTRALKEKAPFWVEKMPEIPELVYDSLRQGKYLQHSVDKIARELQVNHVRQSQSRYLLGIGATLLLSGSFLLVNRPEWGLMPGWLMVGGVVVWLVGWRKTR
What is the function of this protein?
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
What are the official names of this protein?
Probable protein kinase UbiB, Ubiquinone biosynthesis protein UbiB.
What is the protein family that this protein belongs to?
Belongs to the ABC1 family. UbiB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AMIE_PSEAB
Sequence: MRHGDISSSNDTVGVAVVNYKMPRLHTAAEVLDNARKIADMIVGMKQGLPGMDLVVFPEYSLQGIMYDPAEMMETAVAIPGEETEIFSRACRKANVWGVFSLTGERHEEHPRKAPYNTLVLIDNNGEIVQKYRKIIPWCPIEGWYPGGQTYVSEGPKGMKISLIICDDGNYPEIWRDCAMKGAELIVRCQGYMYPAKDQQVMMAKAMAWANNCYVAVANAAGFDGVYSYFGHSAIIGFDGRTLGECGEEEMGIQYAQLSLSQIRDARANDQSQNHLFKILHRGYSGLQASGDGDRGLAECPFEFYRTWVTDAEKARENVERLTRSTTGVAQCPVGRLPYEGLEKEA
What is the function of this protein?
Also exhibits in vitro acyl transferase activity, transferring the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates.
What are the official names of this protein?
Aliphatic amidase, Acylamide amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family.
Protein: URE1_BURM7
Sequence: MTLRLSRRAYAEMYGPTTGDRIRLADTELLIEVERDHTLYGEEVKFGGGKVIRDGMGQSQLPAADVADTVITNAVILDHWGIVKADIAIKHGRIAAIGKAGNPDIQPGVTIAIGAATEIIAGEGLIVTAGGIDTHIHFISPQQIDEALASGVTTMIGGGTGPATGTNATTCTPGPWHMERMLQAADGWPINLGFLGKGNASRPQPLVEQIEAGAIGLKLHEDWGTTPAAIDNCLTVADDTDTQVAIHTDTLNEAGFVEATVAAFKGRTIHTYHTEGAGGGHAPDILKVCGEANVLPSSTNPTRPYTINTLDEHLDMLMVCHHLDPSIAEDLAFAESRIRRETIAAEDILHDLGALSMLSSDSQAMGRVGEVIIRTWQTAHKMKVQRGALAGDGARNDNFRAKRYVAKYTINPALTHGIAHEVGSIEPGKWADLVLWEPAFFGVKPAMIVKGGMIAVAQMGDPNASIPTPQPVHYREMFATRGGALARTSLTFVSQLALDAGIGARYGLAKRLVPVRGCRTVTKRDMIHNAWQPAIRVDPETYDVVADGALLTCEPAAVLPMAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TORD_ECO81
Sequence: MTTLTAQQIACVYAWLAQLFSRELDDEQLTQIASAQMAEWFSLLKSEPPLTAAVNGLENSIATLTVRDDARLELAADFCGLFLMTDKQAALPYASAYKQDEQEIKRLLVEAGMETSGNFNEPADHLAIYLELLSHLHFSLGEGTVPARRIDGLRQKTLTALRQWLPEFVARCHQYDRFGFYAALSQLLQVLVECDNQKG
What is the function of this protein?
Involved in the biogenesis of TorA.  Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor.
What are the official names of this protein?
Chaperone protein TorD.
What is the protein family that this protein belongs to?
Belongs to the TorD/DmsD family. TorD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSPB_FRATM
Sequence: MVIFEKTRGKNSPSVMPSKKGDVSNIPTDMLRTKKPILPEQAELDVVRHYTQLSRKNFCIDTNFYPLGSCTMKYNPRAAHKYASLAGFLERHPYASAQSVQGTLECLYDLQNLIKELTGMTGVSLAPMAGAQGEFAGVAMIKAYHHKRSDFERDEIIVPDAAHGTNPATAKVCGLKVIEIPTKKDGDIDIEALDKVLGPKTAGIMLTNPSTVGVFERNIAVIAKKVHEAGGLLYYDGANLNAIMGKARPGDMGFDVLHMNLHKTFATPHGGGGPGAGPVAVNDKLKEFLPVPMVGKKDDKFVWLEEKDVSNTIGRLSAFNGNIGVLIRAYIYGAMLGGNGLTEASEIATLNANYMMARLKEEGFTIAYPDRRASHEFIVTLKPEFLNYGVTATDFAKCLIDKGVHAPTMYFPLLVPECLLIEPTETENVDSMEKFIQAMVEIRDIAKKDPQYLKGAPYNLPARRLDDVKAAKELDIVWQPK
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 2, Glycine cleavage system P-protein subunit 2, Glycine decarboxylase subunit 2, Glycine dehydrogenase (aminomethyl-transferring) subunit 2.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. C-terminal subunit subfamily.
Protein: FLPA_HALLT
Sequence: MSEPNLPAGVERREIGGETRLATRGPPVYGEPTADGWRAWDPGRSKLGGMFELGFETGLSGGETVLYLGAASGTTVSHVADFAGPTYAVEFAPRPARDLVEAAEPRDRLFPLLKDARTPKRYAHVVESDVDAIVQDVATRGQAEVAVRNARFLADDGRLLLAIKARSEDVTVEPETVFEGALDRLRETYEILETQRLDRFHEDHLGVVATPK
What is the function of this protein?
Involved in pre-rRNA and tRNA processing.  Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA.  Site specificity is provided by a guide RNA that base pairs with the substrate.  Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.
What are the official names of this protein?
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Fibrillarin family.
Protein: PROB1_HUMAN
Sequence: MLTALAPPALPGIPRQLPTAPARRQDSSGSSGSYYTAPGSPEPPDVGPDAKGPANWPWVAPGRGAGAQPRLSVSAQNSRQRHGPGSGFPRGPGSGPRPPQPQLRTLPSGEMEVIFGVGPLFGCSGADDREAQQQFTEPAFISPLPPGPASPAAVPRQSQVPDGGSRWATYLELRPRGPSPAAPAQFECVEVALEEGAAPARPRTVPKRQIELRPRPQSPPRAAGAPRPRLLLRTGSLDESLGPLQAAAGFVQTALARKLSPEAPAPSSATFGSTGRSEPETRETARSTHVVLEKAKSRPLRVRDNSAPAKAPRPWPSLRERAIRRDKPAPGTEPLGPVSSSIFLQSEEKIQEARKTRFPREAPDRTVQRARSPPFECRIPSEVPSRAVRPRSPSPPRQTPNGAVRGPRCPSPQNLSPWDRTTRRVSSPLFPEASSEWENQNPAVEETVSRRSPSPPILSQWNQCVAGERSPSLEAPSLWEIPHSAVADAVEPRSSPSPPAFFPWEAPDRPIGTWGPSPQETWDPMGPGSSIAFTQEAQNGLTQEELAPPTPSAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGSHPVGTLDADKCPEVLGPGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPAPPADPCGEEGGESKTQEPPALGPPAPAHYTSVFIKDFLPVVPHPYEPPEPSFDTVARDASQPNGVLRRRAENSTAKPFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLGGARSSSQRSPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTAPEPAAAVQAPLPREPLALAGRTAPAQPRAASAPPTDRSPQSPSQGARRQPGAAPLGKVLVDPESGRYYFVEAPRQPRLRVLFDPESGQYVEVLLPPSSPGPPHRVYTPLALGLGLYPPAYGPIPSLSLPPSPGPQALGSPQLPWVSEAGPLDGTYYLPVSGTPNPAPPLLLCAPPSSSGPTQPGKGSLFPL
What are the official names of this protein?
Proline-rich basic protein 1.
Protein: COX2_TAMCI
Sequence: MAYPFELGFQDATSPIMEELLHFHDHTLMIVFLISSLVLYIISLMLTTKLTHTSTMDAQEVETIWTILPAIILILIALPSLRILYMMDEINDPSLTVKTMGHQWYWSYEYTDYEDLNFDSYMIPTSDLSPGELRLLEVDNRVVLPMELPIRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQATLTSTRPGLYYGQCSEICGSNHSFMPIVLELVPLKHFENWSSSML
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ENGB_PSEPF
Sequence: MQLKNPILGLCQQSTFMLSAAKVDQCPDDEGFEVAFAGRSNAGKSSALNTLTHASLARTSKTPGRTQLLNFFKLDDERRLVDLPGYGYAKVPIPLKQHWQRHLEAYLGGRESLKGLILMMDIRHPMTDFDLLMLDWAVAAGMPMHILLTKADKLTYGAAKNTLLKVQSEIRKGWGDQVTIQLFSAPKRMGLEEAYTVLAGWMELADKGAELPAE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: RL29_NITHX
Sequence: MAAMKTSDIRAMSPDQMDDAVANLKKERFNLRFQRATGQLENTSRMREARRDIARIKTIAAQKRDAKK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: SYDP_ECOUT
Sequence: MDDLTAQALKDFTARYCDAWHEEHKSWPLSEELYGVPSPCIISTTEDAVYWQPQPFTGEQNVNAVERAFDIVIQPTIHTFYTTQFAGDMHAQFGDIKLTLLQTWSEDDFRRVQENLIGHLVTQKRLKLPPTLFIATLEEELEVISVCNLSGEVCKETLGTRKRTHLASNLAEFLNQLKPLL
What is the function of this protein?
Interacts with the SecY protein in vivo.  May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.
What are the official names of this protein?
Protein Syd.
What is the protein family that this protein belongs to?
Belongs to the Syd family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Loosely associated with the cytoplasmic side of the inner membrane, probably via SecY.
Protein: KGUA_PSEPK
Sequence: MNHSSGTLYIVSAPSGAGKTSLVTALTKDDQQIRVSVSHTTRAMRPGEQHGVNYHFVVHEEFKALIAQGDFLEHAEVFGNFYGTSRSALQQTLDQGYDLILEIDWQGAQQVRKLMPQALSVFILPPSQEALRHRLDGRGQDSEEIIAGRMKEAVSEMVHYDEYDYVIINDDFDTALADLKAVFRSNRLLLKKQQQRHAALLKQMIG
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MET3_ASPCL
Sequence: MSNPPHGGVLKDLLARDAPRHDQLETEAEQLPAIVLTERQLCDLELIMNGGFSPLEGFMNQKDYDNVCENVRLADGNLFSMPITLDVSKAVIDESQLKAGSRVTLRDFRDDRNLAILTIDDIYRPDKAREAKLVFGGDKEHPAIKFLNNTVQEFYIGGKVEAINKLNHYDYVALRYTPAELRVHFDKLGWSRVVAFQTRNPMHRAHRELTVRAARARQANVLIHPVVGLTKPGDIDHFTRVRAYQALLPRYPNGMAVLGLLGLAMRMGGPREAIWHAIIRKNHGATHFIVGRDHAGPGKNSKGEEFYGPYDAQHAVEKYREELGIEVVEFQQVTYLPDTDEYKPKDEVPAGVKTLDISGTELRNRLRTGAPIPEWFSYPEVVKILRESSRPRSTQGFTIFLTGYMNSGKDAIARALQVTLNQQGGRSVSLLLGDTVRHELSSELGFSREDRHTNVQRIAFVAGELTRAGAAVIAAPIAPYEESRNAARDAVTQGGGNFFLVHVATPLEYCEKTDKRGIYAKARRGEIKGFTGVDDPYETPSNAHLTVDVSKQTVRSIVHEIILMLETEGFFDRA
What is the function of this protein?
Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP.  Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids.
What are the official names of this protein?
Sulfate adenylyltransferase, ATP-sulfurylase, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the APS kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APOC1_ROULE
Sequence: MRLILSLPVLAVVLAMVLEGPAPAQAAPDVSSTLESISEKLTEFGRTVADKFRTAVDQIKKSDFPEKTRNWFSEMFNKLKEKF
What is the function of this protein?
Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor.  Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL.  Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP).  Binds free fatty acids and reduces their intracellular esterification.  Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein.
What are the official names of this protein?
Apolipoprotein C-I, Apo-CI, ApoC-I, Apolipoprotein C1.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein C1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PB1F2_I49A1
Sequence: MEQEQDTPWTQSTEHINTRKRGSGQQTQKLERPNSIQLMDHCLRTMNQVDMHKRTASWKQWLSLKNPTPESLKIRVLKRWKLFNKQEWTN
What is the function of this protein?
Plays an important role in promoting lung pathology in both primary viral infection and secondary bacterial infection.  Promotes alteration of mitochondrial morphology, dissipation of mitochondrial membrane potential, and cell death.  Alternatively, inhibits the production of interferon in the infected cell at the level of host mitochondrial antiviral signaling MAVS.  Its level of expression differs greatly depending on which cell type is infected, in a manner that is independent of the levels of expression of other viral proteins.  Monocytic cells are more affected than epithelial cells.  Seems to disable virus-infected monocytes or other host innate immune cells.  During early stage of infection, predisposes the mitochondria to permeability transition through interaction with host SLC25A6/ANT3 and VDAC1.  These proteins participate in the formation of the permeability transition pore complex (PTPC) responsible of the release of mitochondrial products that triggers apoptosis.
What are the official names of this protein?
Protein PB1-F2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB1-F2 family.
What are the subcellular locations of this protein?
Host mitochondrion inner membrane. Host nucleus. Host cytoplasm, host cytosol. Note=Inner mitochondrial membrane in most cells types. Otherwise is detected in the nucleus and cytosol.