PharMolix/UniProtQA huggingface dataset:
Protein: NS1_INBBA
Sequence: MADNMTTTQIEVGPGATNATINFEAGILECYERLSWQRALDYPGQDRLNRLKRKLESRIKTHNKSEPESKRMSLEERKAIGVKMMKVLLFMNPSAGIEGFEPYCMKNPSNSNCPNCNWADYPPTPGKCLDDIEEEPENVDDPTEIVLRDMNNKDARQKIKEEVNTQKEGKFRLTIKRDIRNVLSLRVLVNGTFLKHPNGYKTLSTLHRLNAYDQSGRLVAKLVATDDLTVEDEEDGHRILNSLFERFNEGHSKPIRAAETAVGVLSQFGQEHRLSPEEGDN
What is the function of this protein?
Binds and inhibits the conjugation of the ubiquitin-like G1P2/ISG15 protein to its target proteins.  Since G1P2/ISG15 is an early antiviral protein, NS1 may inhibit the host antiviral response.  Prevents EIF2AK2/PKR activation, either by binding double strand RNA or by interacting directly with EIF2AK2/PKR.  Also binds poly(A) and U6 snRNA.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza B viruses NS1 family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: Y5717_BRADU
Sequence: MTILKWALIFLLVSIVAGVLGFTGISAASADIARFLFYVFVVIFLVLLILGLTIFRA
What are the official names of this protein?
UPF0391 membrane protein bsl5717.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYP_ENDTX
Sequence: MFFSKMLIPTLKEAPSDADIVSVKLMVRSGMIRKLASGFYELLPLGLKVLRKVENIIRQEMNSAGGQEVIFPLVFPKALWLETDRWNAYGKELFKLKDRKDAEFCLAPTAEEVVTDLIRKDIKSYKQLPVMLYQFGTKFRDEIRPRFGVMRSREFLMKDAYSFHADEADLEKYYKTMFDAYTNICIKCGFQFRAVEAASGVIGGSFSHEFMVLTDTGEEEMTWCSCGYGANSAKTECLKIEQSKEEPLPSEEIFTTDVCAIEDVAKLLNLSPKKFIKTMIYIADKKPVAVLVRGDYEINEIKLQTLLGADGMLLADEQTVISVTNAPIGFAGPAGLKNIKIIADLSVAELSNALTGANKKDYHLKNVNFKRDYNADIVADIRKVKRGDTCPRCKKEELKFSRGIEIGHTFKLGDKYSKSMNASYLDANGKEKFIIMGCYGIGVTRILAAIIEQSHDDDGIIWTNNIAPFEVVIVPLNYADEKTKETTEKIYKELSSKGLDVLIDDRDERAGIKFKDADLIGIPYRITISEKNLANGNVELKARRDGKDDAVRLFKPEGVVIELLKIFKK
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYOE_YERPN
Sequence: MMIKQYLQVTKPGIIFGNLISVIGGFLLASKGDIDYPLFLSTLLGVSLVVASGCVFNNYIDRDIDKIMERTKNRVLVKGLIDPKVSLIYASVLGIAGMLLLYVAANALAMMLAVIGFVIYVGVYSLYMKRKSVYGTLIGSLSGAAPPVIGYCAVTGQFDTGALILLLIFSLWQMPHSYAIAIFRFKDYQAANIPVLPVIKGISVTKNHITLYILAFMVATLMLTLSGYAGYKYLVVAAAVSVWWLGMALRGYKATNDSVWARKLFVFSIIAITSLSVMMSVDFNVHSSAVLLTYAG
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GATA_ASHGO
Sequence: MKRALERLRQLPRANERFNIFNSVNLSAAQQVMPSEKPLGNLVVGIKDNIVTKKLPTTCSSGVLAGYMSPYDATVVELLDEAGAVTAGKTNMDEFGMGSGGIHSFFGPTLNPAFPERPTVAGGSSSGSAAAVAAGVVDFALGTDTGGSVRMPAAYTSTVGFKPSYGRVSRHGVIAYAQSLDTVGIGARDVGLVRRVFEVLDRHDPKDPTSLPDELRQQAAALRREKKHLKIGIPAELLHGSVAAEIRERLLVVLDKLQAQGHELYPVSVPAVKNSLLVYYMLAPAEAASNLARYDGIRYGCRDEDLDMSDEVLFAPTRGKFGKEVKNRIVLGNYNLCSGAFKNNYMKAQKLRVELINQFDSIFAFENICTGNKPNPAGVDVLLSLTCMAPPPSLEAFTSKENKSPVNSYINDVFTVPMSLAGLPCISVPLAGMKGVGIQLTAQFADDYGLLDAAEDVMQEQLN
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial, Glu-AdT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: 3SA1_NAJAT
Sequence: MKTLLLTLVVVTIVCLDLGYTLKCNKLIPIASKTCPAGKNLCYKMFMMSDLTIPVKRGCIDVCPKNSLLVKYVCCNTDRCN
What is the function of this protein?
Basic protein that binds to cell membrane and depolarizes cardiomyocytes.  It also shows lytic activities on many other cells, including red blood cells.  Interaction with sulfatides in the cell membrane induces pore formation and cell internalization and is responsible for cytotoxicity in cardiomyocytes.  It targets the mitochondrial membrane and induces mitochondrial swelling and fragmentation (By similarity).  It binds to the integrin alpha-V/beta-3 (ITGAV/ITGB3) with a moderate affinity and inhibits protein kinases C (PubMed:8448165).  It also binds with high affinity to heparin (PubMed:17685633).  It also causes skeletal muscle necrosis after intramuscular injection into mice (PubMed:8342169).
What are the official names of this protein?
Cytotoxin 1, CX1, Cardiotoxin 1, CTX-1, CTX1, Cardiotoxin A1, CTX A1, Cardiotoxin I, Cardiotoxin analog I, CTX I.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type IA cytotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: OTC_RHOP5
Sequence: MSNAPRHFLDLDEMPTKELRAVLDAGVALKAKLKSQKARNTLREKPLEGKTLAMIFERPSTRTRVSFDVGMRQLGGESIMLTGAEMQLGRGETIADTARVLSRYVDAIMIRILNHDALLELAEFATVPVINGLTRRSHPCQVMADLMTFEEHRGPIEGRTIAWTGDDNNVLASWAHAAERFNFTLRIATPPELAPGKPMRDWIKSSGASIVLGTDPEEAVRGADCVLTDTWVSMGDKDGEHRHNLLKPYQVNTQLMSLAKPDALFMHCLPAHRGEEVTDEVIDGPQSVVFDEAENRLHAQKGILAWCFGAVG
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPA_ALIF1
Sequence: MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISGGYISSLLRRGDLEGKPGQMLLLHQVPNILSERVLLVGCGKERELGERQYKDIIKKTISTLNETGSMEAVCFLTELHVKGRDTYWKVRQAVESTKDSLYTFNQFKSNKPETRRPLRKLVFNVPTRRELNLGEKAIAHGLSIASGVKASKDLGNMPPNVANPAYLASQARRLADDYETVTTKIIGEEEMKKLGMTSYLAVGQGSHNESMMSIMEYKGHPDPAAKPIVLIGKGLTFDSGGISIKPSEGMDEMKYDMCGAASVFGAMKALAKLNLPLNVVGVLAGCENMPSSNSYRPGDILTTMSGQTVEVLNTDAEGRLVLCDALTYVERYEPECVVDVATLTGACVVALGHHISGLISNHNPLAHELINASEQSGDRAWRLPMAEEYNEQLSSPFADMGNIGGKAAGTITAGCFLSRFAKKYHWAHIDSAGTAWVSGANKGSTGRPVSLLVQFLLNRSGQENEE
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARNB_ECOL5
Sequence: MSGFLPFSRPAMGVEELAAVKEVLESGWITTGPKNQALEQAFCQLTGNQHAIAVSSATAGMHITLMALEIGKGDEVITPSLTWVSTLNMISLLGATPVMVDVDRDTLMVTPEAIEAAITPRTKAIIPVHYAGAPADIDAIRAIGERYGIAVIEDAAHAVGTYYKGRHIGAKGTAIFSFHAIKNITCAEGGLIVTDNENLARQLRMLKFHGLGVDAYDRHTWGRAPQAEVLTPGYKYNLTDINAAIALTQLVKLEHLNTRRREIAQQYQQALAALPFQPLSLPAWPHVHAWHLFIIRVDEQRCGISRDALMEALKERGIGTGLHFRAAHTQKYYRERFPTLSLPNTEWNSERICSLPLFPDMTTADADRVITALQQLAGQ
What is the function of this protein?
Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase, UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase, UDP-Ara4O aminotransferase, UDP-4-amino-4-deoxy-L-arabinose aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.
Protein: EFTU_STAES
Sequence: MAKEKFDRSKEHANIGTIGHVDHGKTTLTAAIATVLAKNGDTVAQSYDMIDNAPEEKERGITINTAHIEYQTDKRHYAHVDCPGHADYVKNMITGAAQMDGGILVVSAADGPMPQTREHILLSRNVGVPALVVFLNKVDMVDDEELLELVEMEVRDLLSEYDFPGDDVPVIAGSALKALEGDAEYEQKILDLMQAVDDYIPTPERDSDKPFMMPVEDVFSITGRGTVATGRVERGQIKVGEEVEIIGMHETSKTTVTGVEMFRKLLDYAEAGDNIGALLRGVAREDVQRGQVLAAPGSITPHTKFKAEVYVLSKDEGGRHTPFFTNYRPQFYFRTTDVTGVVNLPEGTEMVMPGDNVEMTVELIAPIAIEDGTRFSIREGGRTVGSGVVTEIFE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_ACIF2
Sequence: MPKMKSNRGAAKRFKRTGSGKFKHRQAFLNHILTKKTTKRKRHLRHTLVTSGSDQAALRRMLPYG
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: RL30_STRPF
Sequence: MAQIKITLTKSPIGRKPEQRKTVVALGLGKLNSSVVKEDNAAIRGMVTAISHLVTVEDVK
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: Y052_RICCN
Sequence: MLSRDSSQLTSFNNKDSHDIIEVSQTLNALISIIAKHDHDIARHAQAIADIKKCYNLQMLGILQI
What are the official names of this protein?
Uncharacterized protein RC0052.
Protein: DEOD_LIMRD
Sequence: MSTHINAKMGDYADTVLLPGDPLRAKYIAENFLENVKQVNSVRNAFGYTGEYKGHRISVQGSGMGIPSMSIYINELVREFGVKTIIRVGSCGGIAPDVHVRDVLLAQGSSTDSAVTVNTFGPGFHYAPLADFKLLDTAYHVAGKLGIETKVGDIFAADRFYNDELDMEKLRDYGILGTEMESAGLYLLAAKLHFRALSVLTVSDLIFGDEKATAEERERTFNDMINISLETAIAGK
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: M2OM_RAT
Sequence: MAATASPGAGRMDGKPRTSPKSVKFLFGGLAGMGATVFVQPLDLVXNRMQLSGEGAKTREYKTSFHALTSILKAEGLRGIYTGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTPPGFLLKALIGMTAGATGAFVGPPAEVALIRMTADGRLPADQRRGYKNVFNALIRIAREEGVPTLWRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYFSDNILCHFCAIMISGLVTTAASMPVDIVKTRIQNMRMIDEKPEYKNGLDVLLKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNKAYKRLFLSG
What is the function of this protein?
Catalyzes the transport of 2-oxoglutarate (alpha-oxoglutarate) across the inner mitochondrial membrane in an electroneutral exchange for malate (PubMed:5083502, PubMed:3355813, PubMed:7703504).  Can also exchange 2-oxoglutarate for other dicarboxylic acids such as malonate, succinate, maleate and oxaloacetate, although with lower affinity (PubMed:3355813, PubMed:7703504).  Contributes to several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism (PubMed:5083502, PubMed:3355813).  Maintains mitochondrial fusion and fission events, and the organization and morphology of cristae (By similarity).  Involved in the regulation of apoptosis (PubMed:16291728).  Helps protect from cytotoxic-induced apoptosis by modulating glutathione levels in mitochondria (PubMed:16291728).
What are the official names of this protein?
Mitochondrial 2-oxoglutarate/malate carrier protein, OGCP, alpha-oxoglutarate carrier, Solute carrier family 25 member 11, SLC25A11.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SYP_BURM7
Sequence: MKASRFFIGTLKEAPADAEIVSHKLMVRAGMIRRVAGGIYNYLPVGLRSIRKVEAIVREEMNRAGAIELLMPAVQPAELWQESGRWEQYGPELLRFKDRKQNEFVIGPTHEEVVTDIARNQIKSYRQMPVNFYQIQTKFRDEIRPRFGVMRGREFIMKDAYSFDKDHESLKESYKKMYDAYVRIFTRIGLEFRPVAADNGSIGGSGSHEFHVIADTGEDAIAYCPTSDFAANVEAAEALPLLASRAAPAEAMQKVATPGKAKCEAVAELMGIPLERTIKSIVLATDNEGAEPTIWLLMLRGDHDLNEIKTAKLPGLAGHRFATEAEIVEWFGTPPGYLGPIGTKKPVRVVADRTVANMSDFVVGANEVDYHIAGVNWGRDLPEPVVADIRNVKAGDPSPDGKGALDICRGIEVGHVFQLGTKYSDAMGATFIDESGKAQPMVMGCYGIGITRILGAAIEQNFDDKGIVWPEAIAPFEVVLCPMGYDRSDAVREAADKLYADLAAAGIDVILDDRGERPGVMFADWELIGVPHRLVIGERGLKDGKIEYQGRRDAEATLLPADSAAAAVAEKVRAALAR
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THPR_AQUAE
Sequence: MKVVRAFVGFFTSKSINEVAERIKKEVDLKIMGKWVEPQNVHMTLQFLGDITEAQAIEVIKNLQEISKKNIPFRIKYKGLGVFPDVKRPRVLWIGVSEGANKLTNLAKEVARLNAKKGIIPKNSKNFVPHVTICRIKSYDRKTLNELLRKYRTVEFGEDEVNKIALISSTLTSVGPIYTVVEEFYLGG
What is the function of this protein?
Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.
What are the official names of this protein?
RNA 2',3'-cyclic phosphodiesterase, RNA 2',3'-CPDase.
What is the protein family that this protein belongs to?
Belongs to the 2H phosphoesterase superfamily. ThpR family.
Protein: PAND1_PAEAT
Sequence: MKRTMFKSKIHRATVTHADLHYVGSVTVDLDLLDAANILPGEQVAIVDVTNGARLETYTIAGERGSGVIGINGPAAHLVHENDTVILITYAQMTHEEARAHEPRVVHVNQDNRVIQLGNDPAQGIIPGLLRPPFALNNPAL
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase 1, Aspartate alpha-decarboxylase 1.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COXZ_RHIL3
Sequence: MSENAGTPKKQGRNNGAVVMMCLSFVFGMGAMSYAAVPLYRIFCQVTGYNGTTQRVDQVSSVVLDRTMRVTFDANVAPGLQWDFKPVEREVNPKIGETIQVNFTAENRSNETQRGQAVFNVTPGEAGVYFNKVQCFCFTETDLKPGEKLDMPVVFYIDPEIVKAVESKNIHTVTLSYTFYPKEGPKPVASNEGGAEKIEKKL
What is the function of this protein?
Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.
What are the official names of this protein?
Cytochrome c oxidase assembly protein CtaG.
What is the protein family that this protein belongs to?
Belongs to the COX11/CtaG family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: CYSN_ECO24
Sequence: MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYSEETFTRIRKDYLTFAEQLPGNLDIRFVPLSALEGDNVASQSESMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAVQSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARVDGIRYQVDINNLTQREVENLPLNGIGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPVSQATAAPSEFSAFELELNALVRRHFPHWGARDLLGDK
What is the function of this protein?
With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 1, ATP-sulfurylase large subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
Protein: YABA_STRPB
Sequence: MNKKELFDAFDGFSQNLMVTLAEIEAMKKQVQSLVEENTILRLENTKLRERLSHLEHETVAKNPSKQRKDHLEGIYDEGFHICNFFYGQRRENDEECMFCRELLDRK
What is the function of this protein?
Involved in initiation control of chromosome replication.
What are the official names of this protein?
Initiation-control protein YabA.
What is the protein family that this protein belongs to?
Belongs to the YabA family.
Protein: THIE_PELUB
Sequence: MKQNKINKKFVYLISPNKIPDINFYDDLALVLSSKKISFFQLRLKKETNLNKLIIGKKIKKICNKHKVKFLINDDPLLAKKLNADGCHLGQKDMDLIKARKILKNKIIGVTCHNSINLAKKAINDGADYLAFGAFYATKTKTVKYRASLTVLKSIKKITSLPIVAIGGIKLSNYKKLLLNKANFLAISGYIWNNKKYKPLEAIRKLK
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: LEXA_MYCTU
Sequence: MNDSNDTSVAGGAAGADSRVLSADSALTERQRTILDVIRASVTSRGYPPSIREIGDAVGLTSTSSVAHQLRTLERKGYLRRDPNRPRAVNVRGADDAALPPVTEVAGSDALPEPTFVPVLGRIAAGGPILAEEAVEDVFPLPRELVGEGTLFLLKVIGDSMVEAAICDGDWVVVRQQNVADNGDIVAAMIDGEATVKTFKRAGGQVWLMPHNPAFDPIPGNDATVLGKVVTVIRKV
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  Has been shown to bind to the 14 bp palindromic sequence 5'-CGAACNNNNGTTCG-3'.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: MSBA_FRATH
Sequence: MANMIDKIDLKSQGSSNLSGEMTNHQKVGTLYKRLLLQVKHLWHFLLLAAIGSIFFSAADASMIYLINPILNYGFGPGGGITKQSATILMLMGVGMVGLLALRSVGSFVSQYFIGSLGQKVVYKFRKDIYKRLMGLPASFFDKHSTGQIISRLLYNVDQVTEATSTAIITVVQDGTFVIGLIVVMFVSSWQLSLFLIVVGPFLGLFISIINKKFRNLSRNTQSSMGNVTHTAEETIRNYKEIRIFGAQQKQQNKFFKNLDYTYSQQIRTIALDALTSPVIQIIASLVLAFSLFTIAIFGTNEGDGSSWLTAGSFASFFAAAAAILKPIKNLTKVNVVIQKAVAATEDIFYILDYPAEKETGSKELAKVDGNVTIKDLSFAFGEHKVLSGVSVDIKAGQTVAFVGKSGSGKTTLTSIISRFYTQHEGEILLDGVDTRELTLENLRSHLSIVSQNVHLFDDTVYNNIAFGLSREVSEEEVIDALKRANAYEFVQELSDGINTNIGNNGSKLSGGQRQRISIARALLKNAPVLIFDEATSALDNESERVVQQALESLTKSCTTIVIAHRLSTVENADKIVVMDGGMVVESGKHQELLEQGGLYTRLYQSGLQ
What is the function of this protein?
Involved in lipopolysaccharide (LPS) biosynthesis.  Translocates lipid A-core from the inner to the outer leaflet of the inner membrane.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
What are the official names of this protein?
ATP-dependent lipid A-core flippase, Lipid A export ATP-binding/permease protein MsbA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRMD_MYCCT
Sequence: MKFSIITLFPKIINSYIEESIIKRAINKQAIQIEIIDLRNFSTLNHNQVDDYQYGGGSGMVLMIEPLIKAIESVKTTKSIVLLTTPQGKTLNQSIVKTYSNNYEHIIIVCGHYEGYDERVLDYIDDEISIGDYVITGGELASLILVDSISRLLPNVIKQESYENESFENNLLDHPVYTKPYEFRNKKVPDVLLSGHHQNIKKWREEQQVIKTLKKRPDLIDITKLNKHQLEIYKKMKGEQ
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPD_STACT
Sequence: MAIIAKKYAQALYETSLDKDVLDLMYDEFAAVDEAVIPNQDKLKAFDSDPKNIAEDRNSLVESAFKGINEYLKNMLFVMAENRHLSILPEVFKAFEGLYNQYYNQDFATVESVHELSQDELDKVGEALIQRTGLSKLIITNVINKSLIGGIRAKVGTKVFDGSIQNDLAQIERKFIRTK
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: DPO3B_RICFE
Sequence: MLKLIVETKTLVQSLGFASSVVEKRNVIPEYANIKLSAKDGNLELSSTNMDLYLSQKIAVQVVSEGELTVSTKTLNDIVRKLPDSELTLTDLGTTGLEIKGKNCKFNLFTLPVSSFPPMDSINPEASFKISCTDFAKIIESTKFSISLDETRYNLNGVYLHIKDKEFCSASTDGHRLSISWVTLEKQIKNFGVILPQKSAEEILKIVKDPKNINEDIEILLSSNKIKFICNENTIMLSKLIDGTFPDYSAFIPESSSSKLVINRKIFADSIERIAIITVEKFRAVKLSLSRETLEISAVGEARGNAKEVINSSQDKESFYEYNSDESLAIGFNPQYLEDVLKAVKSDLVELYFSDVSAPVLIKFPENPKDIFVVMPVKV
What is the function of this protein?
Confers DNA tethering and processivity to DNA polymerases and other proteins.  Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA.  Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity.  The beta chain is required for initiation of replication as well as for processivity of DNA replication.
What are the official names of this protein?
Beta sliding clamp, Beta clamp, Sliding clamp, Beta-clamp processivity factor, DNA polymerase III beta sliding clamp subunit, DNA polymerase III subunit beta.
What is the protein family that this protein belongs to?
Belongs to the beta sliding clamp family.
What are the subcellular locations of this protein?
Cytoplasm.