PharMolix/UniProtQA huggingface dataset:
Protein: EX7L_PSEPK
Sequence: MIKDPFERLGLDREVLTVSQLNGRARVLLEDVFRSVWVEGEISNLARPASGHMYFTLKDSGAQVRCALFRQNATRVRQALRDGLAVRVRGKVSLFEGRGDYQLILDTVEPAGDGALRLAFEALKEKLGAEGLFSAERKKPLPAHPQRIGIITSPTGAVIRDIISVFGRRAPQVELNLIPTAVQGREAIAQIVRAIRLADSLGFDALILARGGGSLEDLWCFNEEAVARAVAACVTPIVSAVGHETDVSISDFVADVRAPTPSAAAELLAPDNSGLRQRLDGLQRRLLLRMQNRLTHDRLRLESLTRRLRHPGERLRQRAQRLDDLDMRLRRAFMLNLNQRRERLARLDARLAAQHPGRNLKLLNQRLDSLAERLPRAMREVLKDRRQRFQAQLQTLQVVSPLATLARGYSILLDEQGQAIRSAEQTRNGQRLTARLNEGELLVRVEDNHLTPVTLSLLD
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAB7B_DICDI
Sequence: MTKGRKIIKVVIIGEKSVGKTSILRRYVDKRFVTLKPTIGVDFVMVSENMVTLQLWDTSGQERFRSLEISYYRGADYCILVFDVTNEKTLYDLKLWRDDFIEKTEIRDPILFPFIILGNKIDDPNRVVTEKAAIQWCKDNIGGNLTYFDTSAKDNINIEQVFKHISNQCENQPQSNEIPPEQLISLTEKKSNQSSCC
What is the function of this protein?
Protein transport.  Probably involved in vesicular traffic (By similarity).
What are the official names of this protein?
Ras-related protein Rab-7B.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
Protein: YKGJ_ECOLI
Sequence: MSNLNPCMTCGACCAFFRVSFYWAEADDAGGTIPARLTEQISPFHRCMSGTNQKNPRCIALAGTPGKNACCTIYKNRSSTCREFAMSGENGVVNEACNRARAKYGLTPL
What are the official names of this protein?
Uncharacterized protein YkgJ.
What is the protein family that this protein belongs to?
To A.calcoaceticus putative ferredoxin.
Protein: TGT_HELPY
Sequence: MDFQLQATDNNARAGLLNLAHSQVATPVFMPVGTQGCIKSLDATDAQEILGAKLILANTYHMYLRPGEKVVEELGGLHRFAQFYGSFLTDSGGFQAFSLSDNVKLQEDGIVFKSHIDGSKHLFTPAKVLDIQYSLNSDIMMVLDDLVGLPAPLKRLEESIKRSAKWANMSLEYHKEKNRPSNNLFAIIQGGTHLKMRSLSVGLTHEGFDGYAIGGLAVGESADEMLETIAHTAPLLPKDKPRYLMGVGTPENILDAISLGVDMFDCVMPTRNARNATLFTHSGKISIKNAPYKLDNTPIEENCACYACKRYSKAYLHHLFRAKELTYARLASLHNLHFYLELVKNARNAILEKRFLSFKKEFLEKYNSRSH
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: THI13_YEAST
Sequence: MSTDKITFLLNWQPTPYHIPIFLAQTKGYFKEQGLDIAILEPTNPSDVTELIGSGKVDMGLKAMIHTLAAKARGFPVTSVASLLDEPFTGVLYLKGSGITEDFQSLKGKKIGYVGEFGKIQIDELTKHYGMKPEDYTAVRCGMNVAKYIIEGKIDAGIGIECMQQVELEEYLAKQGRPASDAKMLRIDKLACLGCCCFCTVLYICNDEFLKKNPEKVRKFLKAIKKATDYVLADPVKAWKEYIDFKPQLNNDLSYKQYQRCYAYFSSSLYNVHRDWKKVTGYGKRLAILPPDYVSNYTNEYLSWPEPEEVSDPLEAQRLMAIHQEKCRQEGTFKRLALPA
What is the function of this protein?
Responsible for the formation of the pyrimidine heterocycle in the thiamine biosynthesis pathway.  Catalyzes the formation of hydroxymethylpyrimidine phosphate (HMP-P) from histidine and pyridoxal phosphate (PLP).  The protein uses PLP and the active site histidine to form HMP-P, generating an inactive enzyme.  The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme.
What are the official names of this protein?
4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase THI13, HMP-P synthase, Hydroxymethylpyrimidine phosphate synthase, Thiamine biosynthesis protein 13, Thiamine pyrimidine synthase.
What is the protein family that this protein belongs to?
Belongs to the NMT1/THI5 family.
Protein: COXX_STAAC
Sequence: MSKEHTLSQNISRVNFKELQQIIKMGLVQGNLIPAFAGAWLAVVMTNHSFLSSIPQILLMLFGSTLIMGGACALNNYYDQDIDRIMPSKQNRPTVNNRITDQNLLLLSFGMMLVGEICLFLLNIPSGVLGLMGIVGYVSYYSIWSKRHTTWNTVIGSFPGAVPPLIGWVAIEGQISLTAIALFLVVFCWQPIHFYALAIKRKDEYALANIPMLPSVKGFKRTRVSMFIWLIILLPVPLLLINLGVVFVVLATLLNLGWIALGLTTFKKNSDQTKWATQMFIYSLNYLVIFFVLAVIVSLLTLI
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DBHB_ECOL6
Sequence: MNKSQLIDKIAAGADISKAAAGRALDAIIASVTESLKEGDDVALVGFGTFAVKERAARTGRNPQTGKEITIAAAKVPSFRAGKALKDAVN
What is the function of this protein?
Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
What are the official names of this protein?
DNA-binding protein HU-beta, HU-1, NS1.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: Y3397_YERE8
Sequence: MSIENTLPTYQSLALALNQQAVALTPAEMHGLISGMLCGGSKDDGWRALVHDLTNEGIAFSQALGLPLQQLHEATQEALENEGFMFQLLIPEGEEVTVFDRADALSGWVNHFLLGLGMLQPKLAQVKDEVGEAIDDLRNIAQLGYDEDEDQEELAQSLEEVIEYVRVAAILCHIEFTQEKPTAPEIRKPTLH
What are the official names of this protein?
UPF0149 protein YE3397.
What is the protein family that this protein belongs to?
Belongs to the UPF0149 family.
Protein: UBIQP_AGLNE
Sequence: MQIFVKTLTGKTITLEVESSDTIENVKTKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNNQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIENVKTKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTITGKTITLEVESSDTIENVKTKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIENVKTKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNLQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIENVKTKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIENVKTKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGM
What is the function of this protein?
Ubiquitin exists either covalently attached to another protein, or free (unanchored).  When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains).  Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involved in protein degradation via the proteasome.  Linear polymer chains formed via attachment by the initiator Met lead to cell signaling.  Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed.  When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling (By similarity).
What are the official names of this protein?
Polyubiquitin.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RS20_PHOV8
Sequence: MANHKSSLKRIRQEEKRRLHNRYYAKTMRNTVKKLRATTDKAEAVAMYPGVQKMLDKLAKTNIIHKNKAANLKSKLAAYISKLA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: RS18_HISS2
Sequence: MARYFRRRKFCRFTAENVVEIDYKDIATLKNYITESGKIVPSRITGTRAKYQRQLARAIKRARYLALLPYTDNHQ
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: CCMG_PARDP
Sequence: MARFSPMMLLPVAIFAGFAGLSGWALLRDDPDALPSAMIGREAPSVGEATLPGKVQLTDEMLRQPGVKLVNFWASWCPPCRAEHPTLTELSARLPVYGVDLKDPEGAALGFLSEHGDPFHALAADPRGRVAIDWGVTAPPETFIIDGSGRILHRHAGPLVREDYTNRFLPELEKALAAE
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Also acts as a disulfide oxidoreductase in cytochromes c biogenesis.  The cysteines of apocytochromes c must be in the reduced state for covalent linkage between the two moieties to occur.
What are the official names of this protein?
Thiol:disulfide interchange protein DsbE homolog, Cytochrome c biogenesis protein CcmG.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. DsbE subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: RB8NL_HUMAN
Sequence: MESFMESLNRLKEIHEKEVLGLQNKLLELNSERCRDAQRIEELFSKNHQLREQQKTLKENLRVLENRLRAGLCDRCMVTQELARKRQQEFESSHLQNLQRIFILTNEMNGLKEENETLKEEVKRLRGLGDRPKPRAKEGTSDPPSPLLLPSPGGWKAITEKPPGGHEEAEEDHQGVGLRGEEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPHSSPLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASEPGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNSSPWEET
What are the official names of this protein?
RBBP8 N-terminal-like protein.
Protein: UVRB_GLOC7
Sequence: MNLFHLQAPFQATGDQPQAIAQLVNSIEKGNRFQTLLGATGTGKTFTIAATIEKIGKPTLVLAHNKTLAAQLCNELRQFFPENAVEYFISYYDYYQPEAYIPVSDTYIEKSASINDEIDMLRHSATRSLFERRDVVVVASISCIYGLGMPSEYLKASIGLEVGKEINQRQLLRDLVSVQYSRNDLDLQRGRFRLRGDVLELVPAYEDRVIRVEFFGDEIDAIRYLDPVTGNSLQSLERVNIYPARHFVTPDDQLEAACQGIELELEDRLEELEKQGKLLEAQRLGQRTRYDLELLREVGYCNGVENYSRYLAGREPGQPPECLIDYFPKDWLLVIDESHVTIPQLRGMYNGDQARKKVLIEHGFRLPSAADNRPLKAEEFWEKVNQCVFVSATPGNWEIEQSQGQVIEQIIRPTGVLDPEIFVRPTEGQVDDLLGEIKQRIKRKERVLITTLTKRMAEDLTEYFQERGVKVQYLHSEISSIERIEILQNLREGEFDVLIGVNLLREGLDLPEVSLVAILDADKEGFLRAERSLIQTIGRAARHIQGQAILYADNLTDSMIKAMEETERRRNIQMAHNKRHGITPQPIVTRSSNAILSFLDISRRLNAQQLEKVYDQADELPLEKVPELIGQLEEQMKEAAKKLEFEEAAKYRDRIQHLRDKLLGH
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_PHEZH
Sequence: MLSPKKTKYRKQFKGRIHGTAKGGFTLNFGSYGLKSMEPERITARQIEAARRAITRQMKRQGRVWIRVFPDVPVTGKPAEVRMGSGKGSVEYWAARVHPGRIMFEIDGVPDDVAREALRLGAAKLPVKTRIVTRIDAAVEHA
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: IAAC1_WHEAT
Sequence: MASKSSISPLLLATVLVSVFAAATATGPYCYAGMGLPINPLEGCREYVAQQTCGISISGSAVSTEPGNTPRDRCCKELYDASQHCRCEAVRYFIGRRSDPNSSVLKDLPGCPREPQRDFAKVLVTSGHCNVMTVHNAPYCLGLDI
What is the function of this protein?
Alpha-amylase/trypsin inhibitor.  It could be involved in insect defense mechanisms.
What are the official names of this protein?
Alpha-amylase/trypsin inhibitor CM1, Chloroform/methanol-soluble protein CM1.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I6 (cereal trypsin/alpha-amylase inhibitor) family.
What are the subcellular locations of this protein?
Secreted.
Protein: FK153_ARATH
Sequence: MSPSESAKKNEKISEEATVESKAFSISVEKQTPDLDGLIVEELCMGNPNGKKAEPGKRVSVHYTGKLQGNGKIFDSTVGKSRYKFRLDAGKVIKGLDVGLNGMLVGGKRKLTIPPEMGYGAEGAGSIPPDSWLVFDVELLNVK
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase FKBP15-3, PPIase FKBP15-3, 15 kDa FK506-binding protein, 15 kDa FKBP, FK506-binding protein 15-3, AtFKBP15-3, Immunophilin FKBP15-3, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family.
Protein: H16A7_CYRHA
Sequence: MNTVRVTFLLVFVLAVSLGQADKDENRMEMQGKTEQGKSYLDFAENLLLQKLEELEAKLLEEDSEESRNSRQKRCIGEGVPCDENDPRCCSGLVCLKPTLHGIWYKSYYCYKK
What is the function of this protein?
Probable ion channel inhibitor.
What are the official names of this protein?
U11-theraphotoxin-Hhn1a, U11-TRTX-Hhn1a, Hainantoxin-XVI.7, HNTX-XVI.7, Peptide F4-19.87.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 14 (magi-1) family. 01 (HNTX-16) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CARB_METBA
Sequence: KLGVPQPEGGYATSQKEAIEVAKRIGFPVLVRPSYVLGGRAMEIVYDEMDLERYMKEAVRVSHEHPILIDDFLEAASEIDVDAVCDQKDVIIGAIMEHIEEAGVHSGDSACVIPPQSLSPEVLDQVRDYTRKIALALRVKGLINIQMAEKGGKVYVLEANPRSSRTIPFVSKAVGIPLAKIAAKVIVGHSLKSLGYMDEPKPKHVSIKEVLLPFDKLPGADPVLGPEMKSTGEVMGIDYDFGRAYYKAELAADNVLPLTGKVFLSIRNADKTELVDVAKKLQAAGLELMGTEGTVNYLAQHGVFMDVVKKVHDGSPNVIDMMRRDEVNLIINTPTSKQSRRDGSRIRRAAVDFKVPYITTMQAAIAAAAAIETMKKGEELTIKSINEYHKEMEEENKV
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: YETN_BACSU
Sequence: MDFEIRFLSFYVIQVEGKDEQANKQFKHFQTLDTGEFEESELKDFLDGELKKIVKRKADRHPQSEQVPTKIGHFIVEPGHELDSNPNYNMFNRARLAETKEDFNELSEQFVRTYLDTSAVRGGVFLVASAVPRKYFDESFVFIMKCDFEPKVARISDASSLIKKVEMAITTKNMKSIQYPYMPEEGMVEEGELKIHQASHARYFEDFLKFVEYGESMPEIMKNQVMNMVQEHVYETFEDNSEELKQFEHDIEIWEASEKREIQERLDTHQVIEASAQIIEHTPEAQLKMKVGETEIKGLLADFGDSIHLAKVNGRYVALIEAETISFEKGSSPVEFYKPEGLHEVIERIRNKTEQD
What are the official names of this protein?
Uncharacterized protein YetN.
Protein: LIPA_BACC4
Sequence: MTKQTEYKRKPEWLKIKLNTNENYTGLKKMMRSKNLHTVCEEAKCPNIHECWAVRKTATFMILGAVCTRACRFCAVKTGLPTELDLQEPERVADSVVQMGLKHVVITAVARDDLKDGGAAVFAETVRAVRRKNPFTSIEVLPSDMGGVEENLKMLMDAKPDILNHNIETVRRLSDRVRARAKYERSLEFLRRAKEMQPDIPTKSSIMVGLGETREDLIEAMDDLRANNVDILTLGQYLQPSKKHLPVLKYYPPAEFAELKEIALSKGFSHCEAGPLVRSSYHADEQVRSAKEKTAEAK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PERT_RAT
Sequence: MRTLGAMAVMLVVMGTAIFLPFLLRSRDILGGKTMTSHVISVVETSQLLVDNAVYNTMKRNLKKRGVLSPAQLLSFSKLPESTSGAISRAAEIMETSIQVMKREQSQFSTDALSADILATIANLSGCLPFMLPPRCPDTCLANKYRPITGVCNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPNFLYHGFPLPPVREVTRHLIQVSNEAVTEDDQYSDFLPVWGQYIDHDIALTPQSTSTAAFWGGVDCQLTCENQNPCFPIQLPSNSSRTTACLPFYRSSAACGTGDQGALFGNLSAANPRQQMNGLTSFLDASTVYGSSPGVEKQLRNWSSSAGLLRVNTLHLDSGRAYLPFASAACAPEPGAPHANRTPCFLAGDGRASEVPALAAVHTLWLREHNRLATAFKAINTHWSANTAYQEARKVVGALHQIITMRDYIPKILGPDAFRQYVGPYEGYNPTVNPTVSNVFSTAAFRFGHATVHPLVRRLNTDFQDHTELPRLQLHDVFFRPWRLIQEGGLDPIVRGLLARPAKLQVQEQLMNEELTERLFVLSNVGTLDLASLNLQRGRDHGLPGYNEWREFCGLSRLDTGAELNKAIANRSMVNKIMELYKHADNIDVWLGGLAEKFLPGARTGPLFACIIGKQMKALRDGDRFWWENSHVFTDAQRQELEKHSLPRVICDNTGLTRVPVDAFRIGKFPQDFESCEEIPSMDLRLWRETFPQDDKCVFPEKVDNGNFVHCEESGKLVLVYSCFHGYKLQGQEQVTCTQNGWDSEPPVCKDVNECADLTHPPCHSSAKCKNTKGSFQCVCTDPYMLGEDEKTCIDSGRLPRASWVSIALGALLIGGLASLSWTVICRWTHADKKSTLLITERVTMESGFRKSQESGISPQKAEVQDAEQEPAYGSRVLLCE
What is the function of this protein?
Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4).
What are the official names of this protein?
Thyroid peroxidase, TPO.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. XPO subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RIMK_ALKEH
Sequence: MNILILSRNSRLYSTRRLVEAGRERGHQVRVVDPLRCYMNISPHKPEIHYKGETLENFDGVIPRIGASITFYGTAVLRQFEIMGTFPLNESVAISRSRDKLRSTQLLARKGIGLPMTTFGYSPDDTEDLINLVGGPPMVIKLLEGTQGKGVVLAETQQAAESLIDAFRGLNVHFLAQEYIKEAGGSDIRCFVVGERVVASMRRQAKEGEFRSNIHRGGQASTVRITPEERSMAVRAARIMGLNVAGVDLIRSAHGSLVLEVNSSPGLEGIEKATGKDIAGTIYAFLEKNARQGKTRTRGRG
What are the official names of this protein?
Probable alpha-L-glutamate ligase.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: SYS_JANSC
Sequence: MHDIRAIRETPAAFDAALALRGLSAASADILAIDEARRAAITQAETAQADRNAASKEVGKAKASGDEAEFERLRALVSTKKDEIARLDEEAKAKDAELTAILEALPNLPSPDVPAGADEDDNVEQHRRGTPRAFDFKPLEHFDIPGIAASMDFETAAKLSGARFVTLKGAVARVHRALAQFMLDTHTEENGLTEINAPVLVRDETMYGTGQLPKFAEDSYQTTNGWWLIPTSEVTLTSLDSGNIVDEATLPHRYAAHSLCFRSEAGSAGRDTAGMLRQHQFEKVEMVSVTHPDQSNAEQQRMLACAEGILDKLEIPYRTVLLCAGDMGFGATRTYDIEAWLPGQDTYREISSVSTCGAFQARRMNARFKPSDGGKPEFVHTLNGSGLAVGRCLIAVLENGQNADGSVTLPAALHPWLGGKTRITAEGNLA
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_CHLPD
Sequence: MALEDMEKRYRISDLSRELQVSPQEVLQFIRMNGGKVGSTSSMVNEEMRGMIFGNFSVEKKMVDEAMKIRAEKQRRLTRLEEQSRKTYEKEQQLRDSMHVAPLVPVAPLHVAQDVIVEVAAPPSAQADHTVQAEPAVQTESAVQTESAVQTESAVQTEPAVQTEPAVQTEPEVQTEPAAQTEPEVQTEPAAQTEPAAQTEPAAQTESAVQTEADLSDVGEVSIVPENVEVIDVPELPMVPVMPVKEEPSVNDQLVSFDIPQNIGGLTVVGTLDMMNPFDRSESGKMKARKKNFKEQADALKSEFDTPAGEEKLVDDKLVVKKKPVKAAGDGDTAPAADDALAGKKKPGKKKKKPDVDEKVISANIRTTISGMDDSAGSVSRQKFRKMRRMEREKEHEAAEAFRESQRAIVRVTEYASPHELAELMGVTAKEIIQKCFALGKFVTINQRLDKESLELIALEFGFEAEFISEIEATAVVAEVDDAEDLLIRPPVVTIMGHVDHGKTSLLDYIRNSNVVAGESGGITQHIGAYEVTVEGNRKITFLDTPGHEAFTAMRARGAQVTDIVILVVAADDSVMPQTIEAINHAKAAGVPIVVAINKIDKPAANPEKIKTQLSEAGVLVEDWGGEYQCQEISAKQGIGIEELMGKLLTEAEIRELKGNFSEDVLASGIIIESELDKGKGVISTVLVQRGYLRVGDPFVAGNTMGRVRALMDERSKRIHEAGPSQPVRVLGFEALPQSGDVLTVMASDRDARELAQKRQVIRREHEFRRSTRVKLDSIARQIREGLMKELSVIIKADTDGSIQALADGLMKIHNEEVKVQIIHQGVGQITETDVLLAAASDAIIIGFRVRPNVNAKKLAEKEDLDVRFYSVIYHVLEDVEKALEGMLSPELHEESLGSLEIRQVFRVPKVGNVGGCYALEGKVFRDSKVRLLRDGVQVYDGQLDTLRRFKDDVKEVDAGYECGLSLKNYDDIKVGDIVEAYKIVEKKRKL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOEZ_MYCTO
Sequence: MSTSLPPLVEPASALSREEVARYSRHLIIPDLGVDGQKRLKNARVLVIGAGGLGAPTLLYLAAAGVGTIGIVDFDVVDESNLQRQVIHGVADVGRSKAQSARDSIVAINPLIRVRLHELRLAPSNAVDLFKQYDLILDGTDNFATRYLVNDAAVLAGKPYVWGSIYRFEGQASVFWEDAPDGLGVNYRDLYPEPPPPGMVPSCAEGGVLGIICASVASVMGTEAIKLITGIGETLLGRLLVYDALEMSYRTITIRKDPSTPKITELVDYEQFCGVVADDAAQAAKGSTITPRELRDWLDSGRKLALIDVRDPVEWDIVHIDGAQLIPKSLINSGEGLAKLPQDRTAVLYCKTGVRSAEALAAVKKAGFSDAVHLQGGIVAWAKQMQPDMVMY
What is the function of this protein?
Catalyzes the conversion of the sulfur carrier protein CysO to CysO-thiocarboxylate.  The reaction is thought to proceed in two steps: first, ATP-dependent activation of CysO as acyl-adenylate (CysO-COOAMP), followed by sulfur transfer to give CysO-thiocarboxylate (CysO-COSH) (By similarity).
What are the official names of this protein?
Probable adenylyltransferase/sulfurtransferase MoeZ.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the HesA/MoeB/ThiF family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PTLD_BORPE
Sequence: MAGLSRILLSCTLACLLAGQAAQASVDDPTRAGGDNRVRALRADQARRDVLLTACRDDPGHRRGEPDCVNAERAQALQQWQAAAMTSVDAAFSDLAGALRNAAPRRMEAAIVRLTRQLQPLVYSMMTLLVLLTGYALLARRDRPFEWHIRHALLVAVVTSLALSPDRYLSTVVAGVQDVAGWLSGPWTAPDGAAGRGGLAQLDQFAAQAQAWVAQLAGQAANDANPGSAVNWLLCAMIVAASAGGWLCLAASLLIVPGLIVTLLLSLGPLFLVLLLFPALQRWTNAWLGALVRALVFMALGTPAVGLLSDVLAGALPAGLPQRFATDPLRSTMLAATLCATATLMLLTLVPLASSVNAGLRRRLWPNAAHPGLAQAHRQAAARQYAPRPAAAAAAAGPHQAGTYAASATPAPAPARPAPSFPAHAYRQYALGGARRPPPRVRRDDRPAPAPDRRVLPRKPNLP
What is the function of this protein?
Component of the type IV secretion system ptl required for secretion of assembled pertussis toxin (PTX) through the outer membrane.
What are the official names of this protein?
Type IV secretion system protein PtlD, Pertussis toxin liberation protein D.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL16_CAMLR
Sequence: MLMPKRTKYRKMMKGRNRGYANRGTEFTFGDFALKATEAGRINSRQIEAARIALTRFVKRQGKTWIRVFPDKPLTKKPLETRMGKGKGAVEEWVMNIKPGRIIYEMAGVNEEMARQALTLAMHKLPFKTKFVTRESQNEIY
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: DNJC7_SCHPO
Sequence: MTEVETTHMNAGTESQQEPAELAEKQKAIGNAFYKEKKYAEAIKAYTEAIDLGSDSALAIYYSNRAATYMQIGEFELALCDAKQSDRIKPDVPKTQSRIRQAYEGLSILNEAEVYLKNKQAGLALNALDRLQRRIDSTTQPPMSWMYLKAQVYIFQNDMDRAQKIAHDVLRLNPKNVEALVLRGKVMYYSGENAKAITHFQEALKLDPDCTTAKTLFKQVRKLENTKNQGNDLFRQGNYQDAYEKYSEALQIDPDNKETVAKLYMNRATVLLRLKRPEEALSDSDNALAIDSSYLKGLKVRAKAHEALEKWEEAVRDVQSAIELDASDANLRQELRRLQLELKKSKRKDHYKILGVSKEATDIEIKKAYRKLALVYHPDKNAGNLEAEARFKEVGEAYTILSDPESRRRFDSGVDLEPGMEGGAGMDPFDILRAYQAGGSFPGGGFPGGGFPGGSYNSQGFGMGGGFPGFTSFQFS
What are the official names of this protein?
DnaJ homolog subfamily C member 7 homolog.
What are the subcellular locations of this protein?
Cytoplasm.