PharMolix/UniProtQA huggingface dataset:
Protein: HIS6_ELUMP
Sequence: MLAKRIIPCLDVKDGKTVKGVNFINFRDAGDPVALAAEYSRKGADEIVFLDITASHEKRKTLTDLARRVAAEVNIPFTIGGGVRELEDVSALLAAGADKVSLNSSALKNPNFITEIAKNFGSQVCVCAIDAKENNGKWTCYLNGGRIDTGKDLFVWAKEAENLGAGEILFTSMNHDGVKTGFANEALAKLGQIVNIPVIASGGAGSKEHFKDVFLLGHADAALAASVFHFGEIDISELKTYLRGNRIVVR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASTB_ECO5E
Sequence: MNAWEVNFDGLVGLTHHYAGLSFGNKASTRHRFQVSNPRLAAKQGLLKMKTLADAGFPQAVIPPHERPFIPVLRQLGFSGSDEQVLEKVVRQAPHWLSSVSSASPMWVANAATIAPSADTLDGKVHLTVANLNNKFHRSLEAPVTESLLKAIFNDEEKFSVHSALPQVALLGDEGAANHNRLGGHYGEPGMQLFVYGREEGNDTRPSRYPARQTREASEAVARLNQVNPQQVIFAQQNPDVIDQGVFHNDVIAVSNRQVLFCHQQAFARQSQLLANLRARVNGFMAIEVPATQVSVSDAVSTYLFNSQLLSRDDGSMMLVLPQECREHAGVWGYLNELLAADNPISELKVFDLRESMANGGGPACLRLRVVLTQEERRAVNPAVMMNDTLFNALNDWVDRYYRDRLTAADLADPQLLREGREALDVLSQLLNLGSVYPFQREGGGNG
What is the function of this protein?
Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
What are the official names of this protein?
N-succinylarginine dihydrolase.
What is the protein family that this protein belongs to?
Belongs to the succinylarginine dihydrolase family.
Protein: FABV_BURCJ
Sequence: MIIKPRVRGFICVTTHPVGCEANVKEQIDYVTSHGPIANGPKKVLVIGASTGYGLAARISAAFGSGADTLGVFFERAGSETKPGTAGWYNSAAFEKFATEKGLYARSINGDAFSDKVKQVTIDTIKQDLGKVDLVVYSLAAPRRTHPKTGETISSTLKPVGKAVTFRGLDTDKEVIREVSLEPATQEEIDGTVAVMGGEDWQMWIDALADAGVLADGAKTTAFTYLGEQITHDIYWNGSIGEAKKDLDKKVLSIRDKLAAHGGDARVSVLKAVVTQASSAIPMMPLYLSLLFKVMKEKGTHEGCIEQVYGLLKDSLYGATPHVDEEGRLRADYKELDPQVQNQVVAMWDKVTNENLYEMTDFAGYKTEFLRLFGFEIAGVDYDADVNPDVKIPGIIDTTV
What is the function of this protein?
Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II).  Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH], ENR.
What is the protein family that this protein belongs to?
Belongs to the TER reductase family.
Protein: GSHB_NEIMA
Sequence: MKVLFIADPMASFKTYKDTTYAMMREMAKRGWRLFHTLSGELSVKNGLVVADASAFEFLGAQDDHDKNWFAAADKVQTALKAFDAVIMRTDPPFDMQYLYATQLLTLAEQQGAKVFNSGQAMRDFNEKLAILNFSRFTAPTLVTTRSADVRAFLKEHGDIIIKPLDGMGGMGIFRLTEKDPNIGSILETLMQLDSRTIMAQRYIPEIVHGDKRILIIGGEVVPYALARIPQNGETRGNLAAGGRGVAQELSERDREIAETLAPELKRRGILLAGLDVIGSNLTEVNVTSPTGFQEIMKQKGFDVAAMFADAVAEWSVR
What are the official names of this protein?
Glutathione synthetase, GSH synthetase, GSH-S, GSHase, Glutathione synthase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic GSH synthase family.
Protein: RLMN_MYCTO
Sequence: MVPELMFDEPRPGRPPRHLADLDAAGRASAVAELGLPAFRAKQLAHQYYGRLIADPRQMTDLPAAVRDRIAGAMFPNLLTASADITCDAGQTRKTLWRAVDGTMFESVLMRYPRRNTVCISSQAGCGMACPFCATGQGGLTRNLSTAEILEQVRAGAAALRDDFGDRLSNVVFMGMGEPLANYARVLAAVQRITARPPSGFGISARAVTVSTVGLAPAIRNLADARLGVTLALSLHAPDDGLRDTLVPVNNRWRISEALDAARYYANVTGRRVSIEYALIRDVNDQPWRADLLGKRLHRVLGPLAHVNLIPLNPTPGSDWDASPKPVEREFVKRVRAKGVSCTVRDTRGREISAACGQLAAVGG
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OMPD_SALPA
Sequence: MKLKLVAVAVTSLLAAGVVNAAEVYNKDGNKLDLYGKVHAQHYFSDDNGSDGDKTYARLGFKGETQINDQLTGFGQWEYEFKGNRTESQGADKDKTRLAFAGLKFADYGSFDYGRNYGVAYDIGAWTDVLPEFGGDTWTQTDVFMTGRTTGVATYRNTDFFGLVEGLNFAAQYQGKNDRDGAYESNGDGFGLSATYEYEGFGVGAAYAKSDRTNNQVKAASNLNAAGKNAEVWAAGLKYDANNIYLATTYSETLNMTTFGEDAAGDAFIANKTQNFEAVAQYQFDFGLRPSIAYLKSKGKNLGTYGDQDLVEYIDVGATYYFNKNMSTFVDYKINLLDDSDFTKAAKVSTDNIVAVGLNYQF
What is the function of this protein?
Forms pores that allow passive diffusion of small molecules across the outer membrane.
What are the official names of this protein?
Outer membrane porin protein OmpD.
What is the protein family that this protein belongs to?
Belongs to the Gram-negative porin family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: GLYA_ALKEH
Sequence: MFSRDMTIASFDPELSEAMEAERRRQEDHIELIASENYASPRVLEAQGSVLTNKYAEGYPGKRYYGGCEHVDEAERLAIERAKQLFGADYANVQPHSGSQANAAVYLALLQPGDTILGMSLDHGGHLTHGAKVNFSGRLFNAVQYGVCPDTGELDYAQLERLAKEHQPKMIIGGFSAYSRVVDWQRLRDIADSVGAYLLVDMAHVAGLVAAGVYPSPVQIADVTTTTTHKTLRGPRGGLILARANAEVEKKLNSLVFPGTQGGPLMHAIAGKAVAFKEALEPEFKAYQQQVVANARAMAQGLIERGYKVVSGGTDNHLFLIDLVDKGLTGKAADAALGKAHITVNKNTVPNDPQSPFVTSGLRIGTPAITTRGFKEEECRELAGWMADVLDDIENEDVIARVREQVTQVCRRLPVYQQG
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSH1_AQUAE
Sequence: MWTDRLYRVEPYRMLFQWVKDEGNGIYSVGMASILAALAYPLYSIKIKPVGTKLEYDEALAIIEAGKRVATFPTPLSGIVVDVNEEVIKNPELINKKPYSSWIAKLKATNLEEVKNLQSAKEIVKTVKDFIILEDVDCSIVEE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein 1.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: HIS8_ECOSM
Sequence: MSTVTITDLARENVRNLTPYQSARRLGGNGDVWLNANEYPTAVEFQLTQQTLNRYPECQPKAVIENYAQYAGVKAEQVLVSRGADEGIELLIRAFCEPGKDAILYCPPTYGMYSVSAETIGVECRTVPTLKNWQLDLQGISDKLDGVKVVYVCSPNNPTGQLINPQDFRTLLELTRGKAIVVADEAYIEFCPQASLAGWLAEYPHLAILRTLSKAFALAGLRCGFTLANEEVINLLMKVIAPYPLSTPVADIAAQALSPQGIVAMRERVAQIIAEREYLMAALKEIPCVEQVFDSETNYILARFKASSAVFKSLWDQGIILRDQNKQPSLSGCLRITVGTREESQRVIDALRAEQV
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: SAE2_XENTR
Sequence: MAMIGALPKELAEAVSTSRLLVVGAGGIGCELLKNLVLTGFINLDVIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFCPEANITAYHDSIMNPDYNVEFFKQFTMVMNALDNNAARNHVNRMCLAAGIPLIESGTAGYLGQVTVVKKGVTECYECQPKPTQKTFPGCTIRNTPSEPIHCIVWAKYLFNQLFGEEDADQEVAPDIADPEAAWDPTQAAERANASNVDGDIKRVSTKQWAKSTGYDPIKLFNKLFRDDIKYLLTMDRLWRKRKPPVPLEWSSLHNKENCSETQNESSLQGLKDQKVLDVTSCAQLFSKSVETLREQLREKGNGAELVWDKDDPPAMDFVTAAANLRMHIFSMNMKSRFDVKSMAGNIIPAIATTNAVISGLIVLEGLKILSGNTEQCRTVFLNKQPNPRKKLLVPCSLDPPNPSCYVCAIKPEVTVKLNVHKVTVQMLQDKILKEKFAMVAPDVQIEDGKGTILISSEAGETDANNNRKISEFGIRNSSQLQADDFLQDYTLMINILHSDEMEKDVDFEVVGDVPEKGPQKPSEQSVKNITNGSDDGAQPSTSKAQDQDDVLIVDSDEESPSSSNADINMDSASLKRKLPEEETISSTKRKRLEPPVEEDDDIIALD
What is the function of this protein?
The heterodimer acts as an E1 ligase for sumo1, sumo2, and sumo3.  It mediates ATP-dependent activation of sumo proteins followed by formation of a thioester bond between a sumo protein and a conserved active site cysteine residue on uba2/sae2 (By similarity).
What are the official names of this protein?
SUMO-activating enzyme subunit 2, Ubiquitin-like 1-activating enzyme E1B, Ubiquitin-like modifier-activating enzyme 2.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-activating E1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the cytoplasm and the nucleus, sumoylation is required either for nuclear translocation or nuclear retention.
Protein: Y691_CHLTR
Sequence: MQVLASLFGQSPFAPLQAHLELVSSTINVLFPLFSALKEGDYERVGVLAQLVSSKERQADGMKNDVRRHLASGVFLPVSRAALLEIISIQDSLADCAEDIAILLTVKELQFYPEFEELFFEFLQKTVQSFEAVAKTIREMDRLLESSFGGNRADKTRVLVSEVSNLEHECDLLQRELMKVFFSDDFAIGTKGFVLWMQIIKGISGISNNSEKLAYRVSMTLEEK
What are the official names of this protein?
UPF0111 protein CT_691.
What is the protein family that this protein belongs to?
Belongs to the UPF0111 family.
Protein: LAP1_ASPFM
Sequence: MKVLTAIALSAIAFTGAVAAVITQEAFLNNPRIHHDQEKYLIELAPYRTRWVTEEEKWALKLDGVNFIDITEEHNTGFYPTLHSASYVKYPPKMQYAEEVAALNKNLSKENMKANLERFTSFHTRYYKSQTGIRSATWLFDQVQRVVSESGAAEYGATVERFSHPWGQFSIIARIPGRTNKTVVLGAHQDSINLFLPSILAAPGADDDGSGTVTILEALRGLLQSDAIAKGNASNTVEFHWYSAEEGGMLGSQAIFSNYKRNRREIKAMLQQDMTGYVQGALNAGVEEAIGIMVDYVDQGLTQFLKDVVTAYCSVGYLETKCGYACSDHTSASKYGYPAAMATEAEMENTNKKIHTTDDKIKYLSFDHMLEHAKLSLGFAFELAFAPF
What is the function of this protein?
Extracellular aminopeptidase that allows assimilation of proteinaceous substrates.
What are the official names of this protein?
Leucine aminopeptidase 1, Leucyl aminopeptidase 1, LAP1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family. M28E subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NSP6_ROTHT
Sequence: MNRLLQRRLFLENLLVGVNSTFHQMQKHSINTCCRSLQRILDHLILLQTIHSPAFRLDRMQLRQMRTLACLWIHRRNHDLQATLDAINWISP
What are the official names of this protein?
Non-structural protein 6, NSP6.
What is the protein family that this protein belongs to?
Belongs to the rotavirus A NSP6 family.
What are the subcellular locations of this protein?
Host cytoplasm. Host mitochondrion. Note=Found in spherical cytoplasmic structures, called viral factories, that appear early after infection and are the site of viral replication and packaging.
Protein: URE3_YERP3
Sequence: MQLTPREVEKLMIYTLSDVAFKRKARGLKLNYPEAVSIITVTAMEGARDGKSVEDVMKEASKVLTKDDVMDGVADLIPNVQVEAIFTDGSRLVTVHDPIK
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ODP2_FUSO4
Sequence: MLSAALRRRVLAPTHSALRTGFAAHVVRHYASFPEHQVIKMPALSPTMQAGNIGAWQKKPGDSIAPGDVLVEIETDKAQMDFEFQEEGVIAKILKDAGEKDIPVGSPIAVLVEEGTDISAFEKFSIEDAGGDAAKPAAPKKEEKSESKSESASAPEPTPEPQQYQSQGRLQTALDRLPNISASAKRLAREKGISIDGLKGTGKNGQITEEDVKKAISSPAASSAPSATYEDIPISGMRKTIANRLVESTQTNPHFYVTSSISVSKLLKLRQALNSSADGKYKLSVNDFLIKAIAVASRKVPQVNSSWRDGNIRQFNNVDVSVAVSTPTGLITPIVTGVEGRGLEAISSQVKSLAKKARDGKLKPEEYQGGTISISNMGMNPAVDHFTAVINPPQAAILAVGTTKKVAIPAENEAGVEFDDQITLTASFDHKVVDGAVGAEWLKELKQVLENPLELLL
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (PubMed:34927582).  High pyruvate dehydrogenase complex activity is required for sufficient energy production during germination of conidia (PubMed:34927582).
What are the official names of this protein?
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial, FoDLAT, DLAT.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoacid dehydrogenase family.
Protein: END4_LACPL
Sequence: MLRLGSHVSMKAPDMLLGSANEAASYGANTFMIYTGAPQNTRRKPIDELKIDEAQPIIEAHDLRQIVVHAPYIINLGNTKKPGYFEFATDFLYQEIQRADAVGATQLTLHPGAHIGAGANVAITQIIKGLNAVIRPEQHVQIALETMAGKGTEVGRTFEELAQMIDGVTYNEKLSVTFDTCHTSDAGYAIKDDFDGVLNEFDHVIGLDRLKVIHLNDSKNPQGAHKDRHTNIGMGTIGFDTLNKVAHHPQLPDISKILETPYVGEDKKHQLPPYKYEIAMLRAGQFNPHLIEDIEQQR
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: NEPI_SHIDS
Sequence: MSEFIAENRGADAITRPNWSAVFSVAFCVACLIIVEFLPVSLLTPMAQDLGISEGVAGQSVTVTAFVAMFASLFITQTIQATDRRYVVILFAVLLTISCLLVSFANSFSLLLIGRACLGLALGGFWAMSASLTMRLVPPRTVPKALSVIFGAVSIALVIAAPLGSFLGELIGWRNVFNAAAVMGVLCIFWIIKSLPSLPGKPSHQKQNTFRLLQRPGVMAGMIAIFMSFAGQFAFFTYIRPVYMNLAGFGVDGLTLVLLSFGIASFIGTSLSSFILKRSVKLALAGAPLILAVSALVLTLCGSDKIVATGVAIIWGLTFALVPVGWSTWSTRSLADQAEKAGSIQVAVIQLANTCGAAIGGYALDNIGLTSPLMLSGTLMLLTALLVTAKVKMK
What is the function of this protein?
Involved in the efflux of purine ribonucleosides, such as inosine and guanosine.
What are the official names of this protein?
Purine ribonucleoside efflux pump NepI.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. NepI (TC 2.A.1.2.26) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NANM1_ECOL6
Sequence: MITMKVKNFIYLPFCLFIGTSVAGALPEIPEPFKYGVGGIENGKIYIGLGSLGNNWYMIDTNQSEKKWTKIAQWPTVPREQATATIIDGKIYVFGGIGKDTSGVITLQKDVYSYDIAKDKWEKLMTRPPVSLAGHVSFIHNGHAVSTGGVNENIFNGYFSDVELSKGNSALTEKVNRDYFSKPADDYFLNNHIISYDPSKNQWKNLGTTPFPGTAGSSVIFAEQQIYILGGERKPGLRSVRSWTGELSHDRIKWSELPPVASPEGVSGAYASVIDGNIFLAGGAYFPGAAEKYSNGEYWSHKGLDKAYSKEIYQLIKNDWKKVGSLPEGLAYGVSLPWQGGMLILGGEKKDGKAVSDVIYLKKNDKQIKIVK
What is the function of this protein?
Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers.  Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer.  In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses.
What are the official names of this protein?
N-acetylneuraminate epimerase 1, N-acetylneuraminate mutarotase 1, Neu5Ac mutarotase 1, Sialic acid epimerase 1.
What is the protein family that this protein belongs to?
Belongs to the NanM family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PG176_VACCC
Sequence: MAFDISVNASKTINALVYFSTQQNKLVIRNEVNDTHYTVEFDRDKVVDTFISYNRHNDTIEIRGVLPEETNIGCAVNTPVSMTYLYNKYSFKLILAEYIRHRNTISGNIYSALMTLDDLAIKQYGDIDLLFNEKLKVDSDSGLFDFVNFVKDMICCDSRIVVALSSLVSKHWELTNKKYRCMALANIYLIVFQYLSYLDYDTIYVSIYAGTLRA
What is the function of this protein?
BCL2-like protein which disrupts the host immune response by inhibiting the TLR4 signaling pathway leading to NF-kappa-B activation.  Acts close to the plasma membrane and targets several host TIR-domain containing adapter proteins including MYD88, TIRAP, TRIF and TICAM2.  In turn, blocks the host NF-kappa-B and TRIF-mediated IRF3 activation.
What are the official names of this protein?
Protein OPG176.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG176 family.
Protein: LEU1_XYLFT
Sequence: MNTSISSQPPCIRIFDTTLRDGEQSPGCSMPAQQKLVMARALDALGVDIIETGFPASSQSDYEAMTLIARELRRPTLAVLSRCLQADIETSARALESATKPRLHVFLSTSPLHREHKLRMSKEQVLESVHKHVSLSRTLIDDVEFSAEDATRTEEDFLIEVTRVAIAAGATTINLPDTVGFSTPEEIRNMFTRVIANVEGANKVIFSAHCHDDLGLAVANSLAAIEGGARQIECTINGIGERAGNCALEELTMVLKVRNAFYNIDTSIHTSRIVSTSQLLQRLVGMPVQRNKAVVGANAFAHESGIHQHGMLRHRGTYEIMRPQEVGWVCSHMVLGRHSGRAAVEQRLRALGYLLEEEDLKLVFEEFKQLCEKQRLVTDVDLQVLMQDTTVQHGYRLASMTISDVGNRANALVELSDPQGQRVAETAQGNGPVDALFGALAAATGVKLELDSYQVHSVGIGADARGEANLSVRHNDTQYEGTGTSKDIIEASALAWLEVANRLLRNPENMQNKQNTALA
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: MMPS4_MYCLE
Sequence: MSKRQRGKGISIFKLLSRIWIPLVILVVLVVGGFVVYRVHSYFASEKRESYADSNLGSSKPFNPKQIVYEVFGPPGTVADISYFDANSDPQRIDGAQLPWSLLMTTTLAAVMGNLVAQGNTDSIGCRIIVDGVVKAERVSNEVNAYTYCLVKSA
What are the official names of this protein?
Probable transport accessory protein MmpS4.
What is the protein family that this protein belongs to?
Belongs to the MmpS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TMCAL_GEOKA
Sequence: MKAVGVIVEYNPFHNGHFHHLNETRQKTDADCLIAVMSGNFLQRGEPAIVSKWARAKMALAAGVDVVIELPYAFAVQAAEQFAHGAVQLLAAIGCQELCFGSESGEISAFLSAAKTWLEQKETFDSLIRTGLARGQSFPKAAAEAWQKFGAAPLDLSKPNNVLGFAYVKAIWQNKLAMMPRTIPRLAAGYHDESFSHPSIASATSLRKTLRQTGRLESIAAYVPPATLEQLRQYRETYGRFHDWEVYFPLLKYRLLTATEADLRRIAGVEEGIEHRLKQHIAHAETFAAFIAAVKTKRYTWTRLQRLCAHVLTNFTKEEQAKAANPTYIRLLGMSEAGRRYLKQVKKSAALPLVARASKLNGDSLYEQEKRAAAVYAAAFPEPLYSAALKEEYATAPIYVSGIERK
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDV3_DROME
Sequence: MAELDDFFAKKDKKKSKNKTKFVTADEMVKNLEDGTKREVVKPKKPEVAAGGVAVVGENENSGTKVPESAPPVEEEWKEFEEEQRKDYSGLKIGQLSTISSARSRTAQESSESQAARVPSAPDGGNYNEDDEDSNGYDNADVNKERVGHGPWKKVVPAEEVMQIPVPVEVEKHSSKTYVSPALRYSQQAGSGLGGGPTGGALRPRRAAPDITNTEFFPTLSAARPEEQRKKKNEPAFEEVRHGSRFQRVQESTAAPVAASNRFQSLDDEAS
What are the official names of this protein?
Protein CDV3 homolog, Protein anon-2C9.
What is the protein family that this protein belongs to?
Belongs to the CDV3 family.
Protein: DFB11_MOUSE
Sequence: MRTLCSLLLICCLLFSYTTPAVGDLKHLILKAQLARCYKFGGFCYNSMCPPHTKFIGNCHPDHLHCCINMKELEGST
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Beta-defensin 11, BD-11, mBD-11, Defensin, beta 11.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: A1LB2_LOXAR
Sequence: MGHMVNANYQIDEFVNLGANSIETDVSFDSSANPEYTYHGVPCDCRRWCKKWEYFNNFLKALRKATTPGDSKYHEKLVLVVFDLKAGSLYDNQAYDAGKKLAKNLLQHYWNNGNNGGRAYIVLSIPNLAHYKLITGFKETLKTEGHPELMEKVGYDFSGNDSIDQVANAYKKAGVTGRVWQSDGITNCVASFIRGLDRAKKAVKNRDSSNGYINKVYYWTVDKYATTREALDIGVDGIMTNYPDVIANVLNESAYKEKFRLATYDDNPWETFKN
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LarSicTox-alphaIB2bii, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: STAD3_OPHAA
Sequence: MALRSLFLPNAFPNASSFRGGSRRGAAPRAMPIVMKSNVEVGARNEIAKKPFTPPFEIHEQITHSLPPEKIEIFKSLEGWATDNILIHLRPVEKSWQPQDYLPDPSAESFHDQVKELRQRSKEIPDDYFVALVGDMITEEALPTYQTMLNTLDGVRDETGASLTSWAVWTRAWTAEENRHGDLLNKYLYLTGRVDMRQIEKTIQYLIGSGMDPRTENNPYLGFIYTSFQERATSISHGNTARHAKDYGDLSLAQVCGIIASDEKRHEKAYTKIIEKLFEIDPDATVLAFADMMKKKISMPAHLMYDGRDDNLFKHFSSVAQRLGVYTAKDYADILEFLVERWNVEELTGLSSEGRKAQDYVCTLVPRIRKVDERAQGMAKKGGQTMRFSWIHDREVML
What is the function of this protein?
Converts palmitoyl-ACP to (4Z)-hexadec-4-enoyl-ACP by introduction of a cis double bond between carbons 4 and 5 of the acyl chain.
What are the official names of this protein?
Palmitoyl-[acyl-carrier-protein] 4-desaturase 3, chloroplastic, Acyl-[acyl-carrier-protein] desaturase 3.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: HIP_RUBGE
Sequence: APVDEKNPQAVALGYVSDAAKADKAKYKQFVAGSHCGNCALFQGKATDAVGGCPLFAGKQVANKGWCSAWAKKA
What is the function of this protein?
Specific class of high-redox-potential 4Fe-4S ferredoxins.  Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria.
What are the official names of this protein?
High-potential iron-sulfur protein, HiPIP.
What is the protein family that this protein belongs to?
Belongs to the high-potential iron-sulfur protein (HiPIP) family.
Protein: PPNP_PSEA7
Sequence: MFKVNEYFDGTVKSIAFDMTAGPATIGVMAAGEYEFGTSQLEVMHVIAGALTVRLPGSDEWQNFASGSQFTVPANSKFQLKVAQDTAYLCEYR
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: ARNF_PSE14
Sequence: MCALTSVALVSSAQLGMRWSMSRLPSPGQWLDLQDIGQVQSSAIAVICASITAYALSMLFWLLALRDLPLSRAYSLLSISYALVYTLAATLPFFHETFTVSKTVGVTLIVAGVLTINLRRISSPSLQDLSHENQRFR
What is the function of this protein?
Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
What are the official names of this protein?
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF, L-Ara4N-phosphoundecaprenol flippase subunit ArnF, Undecaprenyl phosphate-aminoarabinose flippase subunit ArnF.
What is the protein family that this protein belongs to?
Belongs to the ArnF family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.