PharMolix/UniProtQA huggingface dataset:
Protein: LEPA_NITMU
Sequence: MQHIRNFSIIAHIDHGKSTLADRIIHLCGGLSDREMEEQVLDSMELERERGITIKAQTAALEYKSRDGSSYLLNLIDTPGHVDFSYEVSRSLAACEGALLVVDASQGVEAQTVANCYTAIEQGVEVIPVLNKIDLPAAEPERVIKEIEDIIGIEAQDAVRASAKTGVGVEDILEAVISRIPPPKGNPEAPLKALIIDSWFDNYVGVVMLVRVMDGVLKPKDRILLMASKTTHLCEQVGVFTPKSRNRESLSAGEVGFIISGIKELKSAKVGDTVTLVDRPAPQPLLGFKEIKPQVFAGLYPVESNQYDALRDALEKLKLNDSSLQYEPETSQALGFGFRCGFLGLLHLDIVQERLEREYDMNLITTAPTVVYQVVLRDGSVIEIENPSRLPDLSKIEQIREPIITATILVPQEYVGSVITLCISKRGIQKNMQYMGRQVMLTYEIPLNEVVMDFFDRLKSTSRGYASLDYEFKEFRASDLVKLDILINGERVDALSLIVHRASSQYRGRELAQKMRELIPRQMFDIAVQAAIGSHIIARESIKALRKNVLAKCYGGDITRKRKLLEKQKAGKKRMKQVGNVEIPQEAFLAILQVGEK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SARX_STAAR
Sequence: MNTEKLETLLGFYKQYKALSEYIDKKYKLSLNDLAVLDLTMKHCKDEKVLMQSFLKTAMDELDLSRTKLLVSIRRLIEKERLSKVRSSKDERKIYIYLNDDDISKFNALFEDVEQFLNI
What is the function of this protein?
Involved in the regulation of virulence genes.  Acts as a repressor of the agr locus and consequently targets genes regulated by the agr system such as sspA, hla and hlb.  Binds directly to the agr promoter region (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator SarX, Staphylococcal accessory regulator X.
What is the protein family that this protein belongs to?
Belongs to the SarA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RARG_NOTVI
Sequence: MMKFSDTASCRDGGERPEEEGKGAGGRSKLRMGKEEFTGSVGKEEAAAVASMSSSKDRICSTSTQLSQLHGFPPSMYPFAFSSNMRGSPPFDLTNGGAYFRSFPTDLPKEMASLSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCQINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEIKEEVVTDSYEMPPEMEALIQKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWHKFSELATKCIIKIVEFAKRLPGFATLTIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFAEQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEALKIYARRRRPNKPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPEAFEDDASPPPKSEQKPIKVEEKPGEKTSTKDP
What is the function of this protein?
Receptor for retinoic acid.  Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes.  The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5 (By similarity).
What are the official names of this protein?
Retinoic acid receptor gamma, RAR-gamma, Nuclear receptor subfamily 1 group B member 3, Retinoic acid receptor delta, RAR-delta.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1141_STRMU
Sequence: MTKNYAYPLDLSWSTEEITSVLSFLNLVEKAYENRVEAALLLKSYQNYKTIVSSKLQEKQIDRNFERVSGYSTYRAVQAAKAKEKGFISLEN
What are the official names of this protein?
UPF0223 protein SMU_1141c.
What is the protein family that this protein belongs to?
Belongs to the UPF0223 family.
Protein: DHQS_METM7
Sequence: MKFGWIKTTGNDSEERIDSVKDALESSIPGILVKREEINSVRELGNIKIVSDSLDADVVLINKGEDLEILKSAKLSGKETAVYVVINTKDDEIYATEVSKLDFVDYVILEGSDWTIIPLENIIADLFGEEIKLVSVVTNVKDAEAAYEILEKGVDGVVLIPKDINEVKDFSKLIERMNSESVKLDYATVTKIEPVGSGDRVCIDTCSMMEMGEGMLIGSYSRGMFLVHSETVENPYVATRPFRVNAGPVHAYILCPENKTKYLSDLKAGDKVLVVNKNGETRESIIGRVKIEKRPLFLVEAEYNGENLRTILQNAETIRLVGEDGKPVSVVDLKVGTKVLIKPDENARHFGMAIKETIIEK
What is the function of this protein?
Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3-dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis.
What are the official names of this protein?
3-dehydroquinate synthase, DHQ synthase, 3-dehydroquinate synthase II.
What is the protein family that this protein belongs to?
Belongs to the archaeal-type DHQ synthase family.
Protein: RBFA_STRM5
Sequence: MPKTFHRTDRVSAQLRRELGTLVHNAVREHGLPSVSVSDVEITRDMAHAKVFVTALMPERSAEAVAGLKELGYRLRMDLARAMKLRHVPELHFHYDDSVDRGEHIDNILRDLPDTLAAEKRREGDDE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPX1_CHLRE
Sequence: MLLTRKNVAVRPARAARRDVRAMSLLGNLFGGGSKPTSSTSNFHQLSALDIDKKNVDFKSLNNRVVLVVNVASKUGLTAANYKEFATLLGKYPATDLTIVAFPCNQFGGQEPGTNAEIKAFASARGFSGAGALLMDKVDVNGANASPVYNFLKVAAGDTSDIGWNFGKFLVRPDGTVFGRYAPTTGPLSLEKYIVELINSR
What is the function of this protein?
May constitute a glutathione peroxidase-like protective system against oxidative stresses.  Hydrogen peroxide, tert-butyl hydroperoxide and cumene, but not phosphatidylcholine hydroperoxide, can act as acceptors.
What are the official names of this protein?
Glutathione peroxidase 1, mitochondrial, CrGPx1.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: VL2_HPV51
Sequence: MVATRARRRKRASVTQLYSTCKAAGTCPPDVVNKVEGTTLADKILQWSGLGIFLGGLGIGTGSGSGGRTGYIPLGGGGRPGVVDIAPARPPIIIDLWHHTEPSIVNLVEDSSIIQSGSPIPTFTGTDGFEITSSSTTTPAVLDITPSAGTVHVSSTNIENPLYIEPPSIEAPQSGEVSDIYLLVHYSGTHGYEEIPMEVFASNVSTGTEPISSTPTPGVSRIAAPRLYSKSYTQVKVTNPDFISKPSTFVTFNNPAFEPIDTSITFEEPDAVAPDPDFLDIITLHRPALTSRRGTVRFSRLGQKATMRTRSGKQIGARVHYYHDISRIAPADELEMQPLLSPSNNYSYDIYADLDEAETGFIQPTHTTPMSHSSLSRQLPSLSSSMSSSYANVTIPFSTTYSVPIHTGPDVVLPTSPTVWPYVPHTSIDTKHSIVILGGDYYLWPYTHLLRKRRKRIPYFFTDGIVAH
What is the function of this protein?
Minor protein of the capsid that localizes along the inner surface of the virion, within the central cavities beneath the L1 pentamers.  Plays a role in capsid stabilization through interaction with the major capsid protein L1.  Once the virion enters the host cell, L2 escorts the genomic DNA into the nucleus by promoting escape from the endosomal compartments and traffic through the host Golgi network.  Mechanistically, the C-terminus of L2 possesses a cell-penetrating peptide that protudes from the host endosome, interacts with host cytoplasmic retromer cargo and thereby mediates the capsid delivery to the host trans-Golgi network.  Plays a role through its interaction with host dynein in the intracellular microtubule-dependent transport of viral capsid toward the nucleus.  Mediates the viral genome import into the nucleus through binding to host importins.  Once within the nucleus, L2 localizes viral genomes to host PML bodies in order to activate early gene expression for establishment of infection.  Later on, promotes late gene expression by interacting with the viral E2 protein and by inhibiting its transcriptional activation functions.  During virion assembly, encapsidates the genome by direct interaction with the viral DNA.
What are the official names of this protein?
Minor capsid protein L2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L2 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host early endosome. Host Golgi apparatus.
Protein: SELA_SALEP
Sequence: MTSETRTLYSQLPAIDRLLHDSAFLSLRDRYGHTQVVDLLRRMLDDARDVIRNTQTLPDWYADWAQEAKLRLENAAQSALRPVINLTGTVLHTNLGRALQAQEAVEAVTQAMRAPVTLEYDLDGAGRGHRDRALATLLCRITGAEDACIVNNNAAAVLLMLAATASGKEVVVSRGELVEIGGAFRIPDVMRQAGCTLHEVGTTNRTHAKDYRQAVNENTGLLMKVHTSNYSIEGFTKTVEEAELAEIGRELDIPVVADLGSGSLVDLSQYGLPKEPMPQQLIAAGVSLVSFSGDKLLGGPQAGIIVGKKAMIAQLQSHPLKRALRADKMTLAALEATLRLYLHPEALAEKLPTLRLLTRSEASIREQAQRLQARLAARYGDEFALEVKPCLSQIGSGSLPVDRLPSAAMTFTPHDGRGSRLEALAARWRMLPVPVIGRIYDGRLWLDMRCLEDESRFMEMMLK
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS5_SULTO
Sequence: MAEEVPVINPEEWKPRTKVGQLVKEGKITSMKEIFEKNYPITEPEIVDVLLPKLKYEVMDIKIVQKQTDAGEISKYKVLIVMGNMDGYVSYGTGKAKQLRVAIQKAIKNAKMNIIPVRRGCGSWECTCGEAHSLPFKVYGKAGSVEVLLMPAPKGTGLVVGPALKTLLTYAGIKDAWSLTRGSTYTTENFIKAGYNALYNTYKFVTPVDWMRRK
What is the function of this protein?
With S4 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: SHCH1_CAEEL
Sequence: MLNVEPSFAEELRSSGVSLSATYLGSVPVVESINVMVSEMRVQVVSECIQHVAATVGVTAAREINPVVSRVIGEVKKENFPVDINISSKMIKIIKQSRLIQRHPFSFFSFGAQGQKGTDTELMFGYIAKNKDGTDRRCHVVFIEDVHKLIDVLTTAINVNTFDAQANASTSNDGFTVPAPPMRHRSSLHRQSFVSNCRAPTVTEDVVGKVWYHGNLSREDAQALLKTEGDFLVRQSDHTPGKYVLSGRTAENEHKHLILLDNHNRVRTRDRTFSNISELIDYHVNNGMAVRSEGRDRETSLNLIRPVPCPGSDDIE
What is the function of this protein?
Scaffold protein which plays an important role in the activation of the JNK pathway composed of mlk-1, mek-1 and kgb-1; by bringing together mek-1 and mlk-1, promotes mlk-1-mediated phosphorylation and activation of mek-1 which in turn phosphorylates kgb-1 (PubMed:18832074, PubMed:18809575, PubMed:22916022).  In addition, negatively modulates the activation of the insulin/IGF-1-like signaling (IIS) probably by inhibiting the insulin receptor daf-2 (PubMed:18832074, PubMed:22916022).  Positively regulates the activity of the transcription factor daf-16/FOXO by both inhibiting IIS and activating the JNK pathway (PubMed:18832074, PubMed:22916022).  Plays a role in maintaining gonadal basement membrane integrity through activation of the JNK pathway components mek-1 and jnk-1 (PubMed:22916022).  Involved in the response to several environmental stresses including heavy metal ions (Cu(2+) and Cd(2+)), heat, oxidative and protein misfolding (ER) stresses (PubMed:18832074, PubMed:18809575).  Plays a role in gonad and germline development following the L1 diapause (PubMed:24746511).  Plays a role in life span and egg laying (PubMed:18832074, PubMed:23072806).  Plays a role in axon regeneration after injury (PubMed:23072806, PubMed:27984580).
What are the official names of this protein?
SHC-transforming protein homolog 1, Src homology 2 domain adapter homolog 1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein. Note=In intestinal cells, enriched in the nucleus.
Protein: NRDR_MYCLB
Sequence: MHCPFCRHSDSRVIDSRETDEGQAIRRRRSCPECGRRFTTVETAVVAVVKRSGVTEPFSRGKVIRGVRRACQGRQVDDDALNLLAQQVEDTVRAAGLPEVPSHEVGLAILGPLRELDEVAYLRFASVYRSFSSADDFEREIEALRAHRRVSTSR
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: NU2C1_PIPCE
Sequence: MIWHVQNENFILDSTRIFMKAFHLLLFHGSFIFPECILIFGLILLLMIDSTSDQKDIPWLYFISSTSLVMSITALLFRWREEPMISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDLITIFVAPECFSLCSYLLSGYTKRDVRSNEATTKYLLMGGASSSILVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGIGFKLSPAPFHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNDGYASMITYMLFYISMNLGTFACIVLFGLRTGTDNIRDYAGLYTKDPFLALSSALCLLSLGGLPPLAGFFGKLYLFWCGWQAGLYFLVSIGLLMSVVSIYYYLKIIKLLMTGRNQEITPHMRNYRRYPLRSNNSIELSMILCVIASTIPGISMNPIIAIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 A, chloroplastic, NAD(P)H dehydrogenase, subunit 2 A, NADH-plastoquinone oxidoreductase subunit 2 A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: CSN6_NEUCR
Sequence: MAAATVNPLMSTLKSDSSLQVALHPLPILEISDYITRSYLRGYKGAIVGALIGQQNGRQITIEHSFSVKTEHTGQNYKVDSEWFTARLDQMKAVHKDRALDFVGWYTLVPKSGPTDAHLPIHSYFYSQNESAVLLGFHIHEILNPVAGDPLPLTIYESNLEIVDGTEASTVEVEGEDREMKDVTAEPSRSIKFRELPYTTETGEAEMIALEFVREGGSANVTTTATNITATEDEGSDKPLMKKVVDTNKGSKRRAVSSDDAAAEAPTTSSAAKGTATDKNRDANLTKAELDYMSALQAKYNAVQMMKKRLDTVISYLQRLPPDYLSSGDASSQQQQQQQQQQQTEGLDQPQYTVPSNKILRQIQALVTNVQLVMSNSTSGQGQGQGERDTDLGALEKELLKETNDVKLVELIADLMSSVKDMKEVGKKFHVVETAKNSKRREQASHGGGERFNPHHPYPGGGGGSSMMREHAGLVGEGSASGSGGSGPAGDLARFDH
What is the function of this protein?
Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes (By similarity).  The CSN complex is involved in the regulation of the circadian clock through its control of the stability of the SCF(FWD1) complex.
What are the official names of this protein?
COP9 signalosome complex subunit 6, Signalosome subunit 6.
What is the protein family that this protein belongs to?
Belongs to the peptidase M67A family. CSN6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PDRP_STRU0
Sequence: MDDRLTIFIISDSLGVTARTIAKACIQQFPNHDNWQFERYSNINNKELLDKVLEKAKDKNVCLMFSLVDDDLARYAQERSEEEHFVYVDLLSNVIKAMSKLSGVEPLGQPGLLRKLDKHYFKRVEAIEFAVKYDDGKDPRGILKADLILLGISRTSKTPLSMYLADKHLKVVNIPIVPEVPLPKELNEVSPKKIVGLTNSVERLSQVRKERLRSLGVSGTASYANKDRIYEEAAYAEEVMRKLKCPIINVSDKAIEETATIILEMIKENQL
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: RL3_METCA
Sequence: MAIGLVGRKCGMTHIFTDAGAAVPVTVIHVEPNRVVQVKTLESDGYRAIQVTTGSKKRSRLTKADAGHYSKAGVEAGRGLWEFRLEDSDQDYTVGTELGVGVFAEGQFVDARARSIGKGFAGVVKRHNFRTQDATHGNSLSHRAPGSIGQNQTPGRVFKGKRMAGHMGDKNITVPNLRIVGIDAERSLLLVKGAVPGTKGADVIVRPAAKK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: SARG_MOUSE
Sequence: MPKRELWPAGLCSEPVTHIGSCGDMMSTTSTRSGSSDSSYDFLSAEEKECLLFLEKTIGSLEAEADSGLSTDESEPATSPRSFRALPTATQQAPQGKPEATDIQQVPVPKRVAQPSCPPESHSLGLRAGSYSLPRNLHLGRSQNLRESATQANSPVSEASEVFLEEPEKGQTSQGAKAKTIQPPAPSQKGTLDLSTVLIPPPEAFQDIRPKESGEESPPKKPGEQTHTPQVHSLERSPHSQKKVEMSSETVSHKATEKGWTEGLQQPQQPPAQSSQPTKAEELSLPSGVKPSIQQTPLTASKARKLPPNIVLKSSRSSFHSHPQNWLSNHTEATDSGPVSSLQEQRKARREALEKLGLPQDQDDPSLLVNKHTSTLKVREAQPQTPSQARAPARPASPALVSGTASAAGKVSPKKAVAPMDSLSKGWIPTQETPPGKVAEAKSMPIPIPKTLKENSSRTQPKPDPRLTLQESSIPGLRQMNFKSNTLERSGVGLSSYLSAAEKKDPSCQTSTSLGKSPFLDKVSPSAFRNSRPRPASLGMGKDFAGIQGGKLVGLEQDQCSQQPSFKGQSYDKLPRPPCISVKISPKGIPDGHRREALKKLGLLKE
What is the function of this protein?
Putative androgen-specific receptor.
What are the official names of this protein?
Specifically androgen-regulated gene protein.
What is the protein family that this protein belongs to?
Belongs to the SARG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AAEB_SALEP
Sequence: MGIFSIANQHIRFAVKLACAIVLALFIGFHFQLETPRWAVLTAAIVAAGPAFAAGGEPYSGAIRYRGMLRIIGTFIGCIAALIIIISMIRAPLLMILVCCVWAGFCTWISSLVRIENSYAWGLSGYTALIIVITIQTEPLLTPQFALERCSEIVIGIGCAILADLLFSPRSIKQEVDRELDSLLVAQYQLMQLCIKHGDSEEVDNAWGDLVRRTAALEGMRSNLNMESSRWVRANRRLKALNTLSLTLITQSCETYLIQNTRPELITDTFRELFETPVETVQDVHRQLKRMRRVIVWTGERETPVTLYSWVGAATRYLLLKRGVISNTKISATEEEILQGEPVVKVESAERHHAMVNFWRTTLSCILGTLFWLWTGWTSGNGAMVMIAVVTSLAMRLPNPRMVCIDFIYGTLAALPLGLLYFLVIIPNTQQSMLLLCLSLAVLGFFIGIEVQKRRLGSMGALASTINIIVLDNPMTFHFSQFLDSALGQIVGCMLAFIVILLVRDKSKDRTGRVLLNQFVSAAVSAMTTNVVRRKENRLPALYQQLFLLMNKFPGDLPKFRLALTMIIAHQRLRDAPIPVNEDLSVFHRQLRRTADHVISAGSDDKRRRYFGQLLDELDIYQEKLRIWEAPTQVTEPVKRLTGMLHKYQNALTDS
What is the function of this protein?
Forms an efflux pump with AaeA.  Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeB, pHBA efflux pump protein B.
What is the protein family that this protein belongs to?
Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LOLD_FUSNN
Sequence: MKMWRHLDMNNIIMKLEDIDKFYMETGNKLHILRKLNLEVKRGEFVSILGKSGSGKSTLLNIMGLLDKIDGGKIWIDDKEVSSLNEMERNNIKNHFLGFVFQFHYLMSEFTALENVMIPALLNNFKNKTEIEKEAKELLEIVGLAERMKHKPNQLSGGEKQRVAIARAMINKPKLILADEPTGNLDEDTGELIFSLFRKINKEHNQSIVVVTHARDLSQVTDRQIFLKKGVLE
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HLDE_PSESM
Sequence: MKLSMPRFDQAPVLVVGDVMLDRYWHGGTSRISPEAPVPVVKVDQIEDRPGGAANVALNIAALGAPASLVGVTGDDEAAESLTNSLKAAGVVARFQRIADQPTIVKLRVMSRHQQLLRIDFEEPFNTDPLALSAEVYSLLDGIKVLVLSDYGKGALKNHQALIQAARKRGIPVLADPKGKDFAIYRGASLITPNLSEFEAIVGHCEDEAQLVTKGAQLMQELDLGALLVTRGEHGMTLLRPDQQALHLPARAREVFDVTGAGDTVISTLAAAIAAGEELPHAVALANLAAGIVVGKLGTAAISAPELRRAIQREEGSERGVLGLEQLLLAVDDARAHKEKIVFTNGCFDILHAGHVTYLEQARAQGDRLIVAVNDDASVSRLKGPGRPINSVDRRMAVLAGLGAVDWVISFPEGTPENLLTHVKPDVLVKGGDYGIDQVVGADIVQAYGGEVRVLGLVENSSTTAIVEKIRGQG
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: RIR2_BHV1C
Sequence: MAEAADAATLTRKYKYFYETECPDLDHLRSLSVANRWLETEFPLADDAKDVARLSGAELEFYRFLFAFLSAADDLVNVNLGDLSELFTQKDILHYYIEQESIEVVHSRVYSAIQLLLFRNDAVARAGYVEGALGDPAVRRKVDWLERRVAAAESVAEKYVLMILIEGIFFSSSFAAIAYLRTHNLFVVTCQTNDLISRDEAVHTAASCCIFDNYLGGERPPPARIYELFREAWKLSASLFGCAPRGSHILDVEAISAYVEYSADRLLAAIQLPPLFGTPPPGTDFPLALMTAEKHTNFFERRSTNYTGTVINDL
What is the function of this protein?
Ribonucleoside-diphosphate reductase holoenzyme provides the precursors necessary for viral DNA synthesis.  Allows virus growth in non-dividing cells, as well as reactivation from latency in infected hosts.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
What are the official names of this protein?
Ribonucleoside-diphosphate reductase small subunit, Ribonucleotide reductase small subunit.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: PURL_GLUOX
Sequence: MSVTIDAQLAQSFGLTGEEYDKLVTIMGRTPSFTELGIFSVMWSEHCSYKSSRIHLKTLPTKAPWVIHGPGENAGVVDIGEGLAAVFKMESHNHPSFIEPYQGAATGVGGILRDVFTMGARPVANLNALRFGDPKHAGTRRIVDGVVRGVGGYGNCVGVPTVGGEVNFHKAYDGNPLVNAMTVGVAKQDKIFLSAAAGVGNPVVYVGSKTGRDGIHGATMSSAEFDEEAASKRPTVQVGDPFIEKLLIEACLELMATDAIVAIQDMGAAGLTSSAVEMAGKGGVGIELNLDAVPQREPNMSAYEMMLSESQERMLMVLKPERTEVARAIFAKWELDFAVIGELTDTGRITIRHKGEVEADIPLAPLADEAPVYNRPTVPLKAPARIETPADPEGIEKALLTLVGCPDLASRAWVWNQYDGSVGGNTARRPGAADAAVVRVEGTRLGLALTTDCTPRYCQADPKTGGAQAVAEAWRNITATGATPLAVTDNLNFGNPERPEIMAQFADAIKGMGDACRALDFPVVSGNVSLYNETRSPSGEAQAILPTPAIGALGVLADASKSIGLAMPDAHDLVLVGGIRGELGQSLWLREICQREDGAPPVVDLAVERRNGDFVRSQIGAGAVAACHDIADGGLLVTVAEMVMASGVGCTLEAAPTDVAAHAFWFGEDQGCYVIATSDGAALVAAAEKANVLAMRLGRSGGTDLELPGTVRVSAERLREINAAFFPRFMGEGA
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOF_PSEAE
Sequence: MTLTSIGPANRMARSAETHPLTWRLREDAQPVWLEEYQSKDGYAAARKALTQMAQDDIVQTVKDSGLKGRGGAGFPTGVKWGLMPKDESLNIRYLLCNADEMEPNTWKDRMLMEQLPHLLVEGMLISARALKAYRGYIFLRGEYVDAARNLNRAIDEAKAAGLLGKNILGSGFDFELFVHTGAGRYICGEETALINSLEGRRANPRSKPPFPAAVGVWGKPTCVNNVETLCNVPAIVGNGVDWYKTLARPGSEDMGTKLMGFSGKVKNPGLWELPFGVSARELFEDYAGGMRDGFQLKAWQPGGAGTGFLLPEHLDAQMFAGGIAKVGTRMGTGLAMAVDDSINMVSLLRNMEEFFARESCGWCTPCRDGLPWSVKLLRALERGEGQPGDLETLEQLVNFLGPGKTFCAHAPGAVEPLGSALKYFRAEFEAGISRQPSAAPRPATVGA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit F, NADH dehydrogenase I subunit F, NDH-1 subunit F.
What is the protein family that this protein belongs to?
Belongs to the complex I 51 kDa subunit family.