PharMolix/UniProtQA huggingface dataset:
Protein: AROC_POLSJ
Sequence: MSGSTFGNLFAVTNFGESHGPAIGCVIDGCPPGLALTEADIQTDLDRRRPGTSRHVTQRNEPDAVEILSGVYEGKTTGTPICLLIRNTDQRSKDYGNILETFRPGHADYSYLHKYGRRDPRGGGRASARLTAPMVAAGAVAKKWLAEKYGTSFRGCMAQIGDIAIPFESWEHVPRNPFFAPVADVSHLEDYMDALRKAGDSCGARIRVTASGVPVGLGEPLFDKLDADIAFAMMGINAVKGVEIGAGFASVTQRGTTHGDSLSPEGFLSNNAGGVLGGISTGQDLEVSIAIKPTSSIITPRQSIDTAGNPAEVVTKGRHDPCVGIRATPIAEAMLALVVMEHALRQRAQNADVTVSTPDIMRARG
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: BIOB_BACVZ
Sequence: MNQWMDLAERVLDGAEVTNQEALAILNCPDEDLLLLMHAAFHIRKRFYGKKVKLNMIMNAKSGLCPENCGYCSQSSISKAPIESYRMVDKHILLKGAKRAHDLNIGTYCIVASGRGPSNREVDQVVDAVKEIKETYGLKICACLGLLKPEQAERLKQAGVDRYNHNINTSQRNHSNITTSHTYDDRVNTVETAKQSGMSPCSGVIVGMKETKQDVIDMANSLKALDADSIPVNFLHAIDGTPLEGVSELHPVYCLKVLALFRFINPSKEIRISGGREVNLRSLQPLGLYAANSIFVGDYLTTAGQQETEDHQMLHDLGFEVESVEEMKAGLQSACNTEV
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: ICIC_HIRME
Sequence: TEFGSELKSFPEVVGKTVDQAREYFTLHYPQYDVYFLPEGSPVTLDLRYNRVRVFYNPGTNVVNHVPHVG
What is the function of this protein?
Inhibits both elastase and cathepsin G.
What are the official names of this protein?
Eglin C.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I13 (potato type I serine protease inhibitor) family.
Protein: THIG_ECO8A
Sequence: MLRIADKTFDSHLFTGTGKFASSQLMVEAIRASGSQLVTLAMKRVDLRQHNDAILEPLIAAGVTLLPNTSGAKTAEEAIFAAHLAREALGTNWLKLEIHPDARWLLPDPIETLKAAETLVQQGFVVLPYCGADPVLCKRLEEVGCAAVMPLGAPIGSNQGLETRAMLEIIIQQATVPVVVDAGIGVPSHAAQALEMGADAVLVNTAIAVADDPVNMAKAFRLAVEAGLLARQSGPGSRSHFAHATSPLAGFLEASA
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPS_DESVH
Sequence: MIVGIGIDITEIDRIAKGWGRFGDRFARRILHPHEVVRMPAANPVAFLAGRFAVKEAAVKALGTGFSGGIGPRDIEVGVAPAGAPQLVLHGKAAARMEALGATRTHVSLTHGRDTAAAVVILES
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYDND_ACIBT
Sequence: MMRTHYCGSLTEAQIDQTVTLCGWVHRRRDHGGVIFLDMRDRDGLVQVVIDPDTPEAFATADKARSEYVLKITGRVRRRYEGTENPNMVSGQIEVLGKEIEVLAASETPPFPLNDDTINVSEEHRLKYRFLDIRRPEMLERLRFRSKVTNLIRNYLDDHGFLDVETPILTRATPEGARDYLVPSRVQNGSFYALPQSPQLFKQLLMVGGIDRYYQIAKCFRDEDLRADRQPEFTQIDIETSFLNDDDIMDLMEGMTIKLFNDLLGVKFEKFRRMPYSEAMRDYASDKPDLRIPLKLVDVADLMQEVEFKVFAGPAKDPKGRIAALRVPGAGSLTRSQIDEYTKFVGIYGAKGLAYIKVNEIEKGIEGLQSPIVKFIEPIVMQLLERVGAENGDIVFFGADKAKIVNDAMGALRVKIGHDLNLATCEWAPLWVVDFPMFEETDDGKWTSVHHPFTLPKSSVEDVKSNPGEALSVAYDMVLNGTEVGGGSLRIYTLEMQKAIFEALGISDEEAEEKFSFLLNALRYGAPPHGGLAFGLDRLVMLMTGATSIRDVIAFPKTKTAECPLTQAPAPVEANQLRDLGIRLREQQKKEA
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AHPC_STAAC
Sequence: MSLINKEILPFTAQAFDPKKDQFKEVTQEDLKGSWSVVCFYPADFSFVCPTELEDLQNQYEELQKLGVNVFSVSTDTHFVHKAWHDHSDAISKITYTMIGDPSQTITRNFDVLDEATGLAQRGTFIIDPDGVVQASEINADGIGRDASTLAHKIKAAQYVRKNPGEVCPAKWEEGAKTLQPGLDLVGKI
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Alkyl hydroperoxide reductase C, Peroxiredoxin, Thioredoxin peroxidase.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUON_SYNC1
Sequence: MTWNMLLALLPLLVLFGGSITVLFLSERRALLSAAMCAVVAAGFAWWPASLEAAGTPLVASNLFARGCLTLWALLGAATCLLSDRYRGSRKLAAREYAALTLFAVLGMAILSASTSLVSLFLGLESMTLAFYVLIAVDRENPTGAEAGLKYLLPGFLASALLAFGIALVYAATGTFELSAAISLSMAGAPMPSIALLGWTLIMAAAAFKASLAPFHLWTPDVYQGASAPIAGFLASGSKGAVFAVLLGSAPLALIVPLRPLLGGLAALSMIWGTLAALRQTNLKRMLAYSSVVHMGYLVLAVLSNRSAGMEAGLFYLLTYSAATVGTFGLLASMVDSGGEPQDYAALEGLAGRSPWRAVLLTGLLLSLAGFPPLAGFMGKFVLFGAALQSGYVGLVVLALLSSLISCYYYLRPVLYLFRVRQGAPTVPAFNNCERLIFVLCAGVTLVAGLYPGPFFRWFGAMLP
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VPU_HV1JR
Sequence: MQPLQILAIVALVVAGIIAIIVWSIVLIEYRKILRQRKIDRLIDKIRERAEDSGNESEGDQEELSALVERGHLAPWDINDL
What is the function of this protein?
Enhances virion budding by targeting host CD4 and Tetherin/BST2 to proteasome degradation.  Degradation of CD4 prevents any unwanted premature interactions between viral Env and its host receptor CD4 in the endoplasmic reticulum.  Degradation of antiretroviral protein Tetherin/BST2 is important for virion budding, as BST2 tethers new viral particles to the host cell membrane.  Mechanistically, Vpu bridges either CD4 or BST2 to BTRC, a substrate recognition subunit of the Skp1/Cullin/F-box protein E3 ubiquitin ligase, induces their ubiquitination and subsequent proteasomal degradation.  The alteration of the E3 ligase specificity by Vpu seems to promote the degradation of host IKBKB, leading to NF-kappa-B down-regulation and subsequent apoptosis.  Ion channel activity has also been suggested, however, formation of cation-selective channel has been reconstituted ex-vivo in lipid bilayers.  It is thus unsure that this activity plays a role in vivo.
What are the official names of this protein?
Protein Vpu, U ORF protein, Viral protein U.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 VPU protein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass type I membrane protein.
Protein: I1BD_CONRA
Sequence: GCKKDRKPCSYHADCCNCCLSGICAPSTNWILPGCSTSTFT
What is the function of this protein?
Iota-conotoxins bind to voltage-gated sodium channels (Nav) and act as agonists by shifting the voltage-dependence of activation to more hyperpolarized levels (By similarity).  Both natural (L-Thr form) and synthetic (D-Thr form) peptides cause paralysis and death following intracranial injection and grooming and hypersensitivity upon intraperitoneal injection into mice.  The L-Thr form of the peptide is 7-fold more potent than the D-Thr form.  Both natural peptide (L-Thr form) and synthetic peptide (D-Thr form) are active on nerve, and on muscle.
What are the official names of this protein?
Iota-conotoxin-like r11d, R11.8.
What is the protein family that this protein belongs to?
Belongs to the conotoxin I1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GREA_HALH5
Sequence: MAEEKKHYMTLEGKKKLEEELEYLKTERRKEVVERIKIARSFGDLSENSEYDSAKEEQAFVEGRISQIEKMIRNAEIIEESEGDANVVSLGKTVKFVEIPDGEEEEYTIVGSAESDPFEGKISNDSPMAQSLLGHTIDDVVIVNTPGGEMEVKILEIR
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: RDRP_SCV23
Sequence: MHHKVNVKTQREVHFPMDLLQACGASAPRPVARVSRATDLDRRYRCVLSLPEERARSVGCKWSSTRAALRRGLEELGSREFRRRLRLADDCWRAICAAVCTGRKFPSFSVTDRPARARLAKVYRMGRRLLVGVVCRGESVVSDLKQECADLRRVIFEGSTRIPSSSLWGLVGVLGWTSPERAMQLTFIGRALPYGSPDVERRALASHAATLSIPAECHPNYLVAAEQFAKSWADDNLPRKFRIYPIAVQESSCMEYSRAQGGLLQSFRKGFVGYDPAAPSADPDDLELAKERGFSRIRASWYSTFRYRGELKSTNQSLEARVAVVPERGFKARIVTTHSASRVTFGHQFRRYLLQGIRRHPALVDVIGGDHRRAVETMDGDFGLLRPDGRLLSADLTSASDRIPHDLVKAILRGIFSDPDRRPPGTSLADVFDLVLGPYHLHYPDGSEVTVRQGILMGLPTTWPLLCLIHLFWVELSDWAPARPNHSRGFVLGESFRICGDDLIAWWRPERIALYNQIAVDCGAQFSAGKHLESKTWGIFTEKVFTVKPVKMKVRVRSEPSLKGYVFSRSSAFSCRMGGKGITGIRAARLYTIGAMPRWSRRIRDVYPGSLEHRTASQRYGEPVTVYRFGRWSSAIPLRWAVRAPTRTVGNPVQSLPDWFTVGPAASSVAADSNAFGAVSRVLRRMFPGLPRKLASAGIPPYLPRVFGGGGLVKSTGLTTKIGAVASRRWMSRIGHDLYRSRERKSTLGRVWTLSTSPAYAASLHEVEKFMDRPDIILTRKCRNPMLKHARELGLFEEVFESRVGGGILWASLNGKALVESHSPSILQVSRNLRRSLACPSGGFLRPSAPIGKLVQRHTLPRGTVWFLESSATDSARQGGMGLPPPPPPPLGGGGMAGPPPPPFMGLRPESSVPTSVPFTPSMFSERLAALESLFGRPPPS
What is the function of this protein?
RNA-directed RNA polymerase that replicates the viral (+) and (-) genome.
What are the official names of this protein?
RNA-directed RNA polymerase, p104.
What are the subcellular locations of this protein?
Host cytoplasm. Note=The virus has no extracellular transmission pathway. It exists as a ribonucleoprotein viral particle in the host cytoplasm and can be transmitted through mating or cytoplasmic mixing (cytoduction).
Protein: RL18_FRAT1
Sequence: MDKKTARLSRSKRTRIKLRELGHTRLCVYRTPRHVYAQVISGDGSTVLVAASTVEKDVKAKCKYTGNVESAAIVGEIIADRCKEKGISQVAFDRSGYKYHGRVKALVEAAREHGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: Y050_SERP5
Sequence: MSEIALTVSMLALVAVLGLWMGNWKIYGVGLGIGGVLFGGIIVGHFAQSWQLNLNGDMLHFIQEFGLILFVYTIGIQVGPGFFSSLRVSGLRLNGFAILLVLVGGLVAAVVHKLFAVPLPIILGVFSGAVTNTPALGAGQQILTDLGSDPALVDRMGMGYAMAYPFGICGILLVMWLIRLFFRINIEQEAQAFASSLGNQRELLHTMNVAVRNPNLQGMAIKNVPLLNGEDIICSRLKRGDLLMVPAPLEKLELGDYLHLVGKRESLENARLVIGEEVDVSLSTRGTELQVVRAVVTNEKVLGSKIRDLNLKQKYDVVISRLNRSGVELVAGSNVTLQFGDILNLVGRPESIEAVAAIVGNAQQKLQQVQMLPVFIGIGLGVLLGSIPLFIPGFPAALRLGLAGGPLVAALILGRIGSIGKLYWFMPPSANLALRELGIVLFLAVVGLKSGGNFVDTLINGEGLAWIGYGALITAIPLFSVGVLARMVGKMNYLTLSGMLAGSMTDPPALAFANGLHPTSGAAALSYATVYPLAMFLRIMSPQLLAVLFWAM
What are the official names of this protein?
Putative transport protein Spro_0050.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family. YidE subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MPP3_MOUSE
Sequence: MPVLSEDSGLHETLALLTSQLRPDSNHREEMGFLRDVFSEKSLSYLMKIHEKLRYYERQSPTPVLHSAMALAEDVMEELQAASVHSDERELLQLLSTPHLRAVLMVHDTVAQKNFDPVLPPLPDNIDEDFEEESVKIVRLVKNKEPLGATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNGIAVLHKRPDEISQILAQSQGSITLKIIPATQEEDRFKDSKVFMRALFHYDPREDRAIPCQEAGLPFQRRQVLEVVSQDDPTWWQAKRVGDTNLRAGLIPSKQFQERRLSYRRTTGTLPSPQNFKKPPYDQPCDKETCDCDGYFKGHYVAGLRRSFRLGCRERLGGSQEAKVPTGAESQVLLTYEEVARYQHQPGERPRLVVLIGSLGAHLHELKQRVVAEDPQQFAVAVPHTTRPRKSHERDGVEYHFVSKQAFEADVHHNKFLEHGEYKENLYGTSLEAIQAVMAKNKVCLVDVEPEALRHLRTPEFKPYVIFVKPAIQERRKTPPVSPDSEDIASSLDEQQQEMAASAAFIDQHYGHLIDTVLVRQDLQEPAASSELS
What is the function of this protein?
Participates in cell spreading through the phosphoinositide-3-kinase (PI3K) pathway by connecting CADM1 to DLG1 and the regulatory subunit of phosphoinositide-3-kinase (PI3K) (By similarity).  Stabilizes HTR2C at the plasma membrane and prevents its desensitization (PubMed:16914526).  May participates in the maintenance of adherens junctions (PubMed:23893895, PubMed:23658188).
What are the official names of this protein?
MAGUK p55 subfamily member 3, Discs large homolog 3, Protein MPP3.
What is the protein family that this protein belongs to?
Belongs to the MAGUK family.
Protein: PURA_RHOJR
Sequence: MPAIVLIGAQWGDEGKGKATDLLGGRLQWVVRYQGGNNAGHTVVLPNGDKFALHLIPSGILTPGVTNVIGNGVVVDPGVLLTELAGLDERGVDTSRLLLSADAHLIMPYHVAIDKVTERFLGAKKIGTTGRGIGPCYQDKLARVGVRVQDVLDEKILTQKVEAALEFKNQVLVKIYNRKALDPQQVVDEVLEQADGFKHRIADTRLQLNEALERGETVLLEGSQGTLLDVDHGTYPYVTSSNPTSGGAAVGSGIGPTKITTVLGILKAYTTRVGSGPFPTELFDQNGEYLAKTGGEVGVTTGRARRTGWFDAVIARYATRVNGITDYFLTKLDVLSSLDTIPICVGYDVDGVRYDEMPMSQTDVHHAKPIYEEMPGWWEDISHARTFEELPKNAQNYVLRLEELSGAYISCIGVGPGRDETIVRRDVVR
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYF5_BOVIN
Sequence: MDMMDGCQFSPSEYFYDGSCIPSPDGEFGDEFEPRVAAFGAHKADLQGSDEDEHVRAPTGHHQAGHCLMWACKACKRKSTTMDRRKAATMRERRRLKKVNQAFDTLKRCTTTNPNQRLPKVEILRNAIRYIESLQELLREQVENYYSLPGQSCSEPTSPTSSCSDGMPECNSPIWSRKSSSFDSVYCPDVPNVYATDKSSLSSLDCLSSIVDRITNSEQPGLPLQDPASLSPVASTDSQPATPGASSSRLIYHVL
What is the function of this protein?
Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation.  Together with MYOG and MYOD1, co-occupies muscle-specific gene promoter core region during myogenesis.  Induces fibroblasts to differentiate into myoblasts.  Probable sequence specific DNA-binding protein (By similarity).
What are the official names of this protein?
Myogenic factor 5, Myf-5.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS28_METJA
Sequence: MEDEFVYKEAVAAEVIEVIGRTGVTGGIIQVRCKILGGKDTGRVLVRNVKGPVKVGDIIMLRETEREARPLDRRR
What are the official names of this protein?
30S ribosomal protein S28e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS28 family.
Protein: CAEH2_ORYSJ
Sequence: MGMAAAGGYGRVLWLHGSGQTGEESRAQVAPYFAAPELASVRFSFPTAPTSSIPCYGGEVITAWFAIPEVPITARTARDEKEVLKAVERVHEMLDGEVAAGTSPSNIFVCGLSQGGALAIASVLLYPMTLGGCVVFSGSLPLSKTFAESIPSEARKTPVLWFHGMADGVVLFEAGHAGCAFLQEIGMHCEFKAYPALGHTLVDEELQYFRQWIKDRLSQGTGVPVPSLSDKMDLQ
What is the function of this protein?
Possesses carboxylesterase activity in vitro.
What are the official names of this protein?
Probable carboxylesterase Os04g0669600.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.
Protein: RRF_THISH
Sequence: MTDSIKKDAKARMGKSIESLRNELAKIRTGRAHTSLLDHVMVEYYGSDVPISQVANVNVEDARTLTVTPWEKTMVSKVEKAIMTSDLGLNPSSMGTVIRVPMPALTEERRRDLVKVVRGEAENARVAIRNIRRDANNALKALVKGKEISEDDERRAQDEIQKLTDSHIEEVDKVLAEKEKELMEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIA_FRATH
Sequence: MNKQQLKAYFMLMRLHRPIPILLILWPTLTALVLASHGLPDISYLVIFTIGVVVMRTVGCIINDIADVDFDKHVARTNTRPLTSGQLSIKNAIWLCISLTLVAFICVLFLNLYTILLSFVALFLAILYPFCKRFFAIPQLILGLAFNFGIFMAFSAIQNQIPVEAWIFYIATICWTIAYDTIYALADREFDLEIGIKSSAVLFGNKVFRYILLFNFLSLLLLIILGIYCDFNSFFYLGVVICSLFFVRNYFLYKKLGITNCINAFSANHWIGLIIFIIAVIQYI
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UBP11_SCHPO
Sequence: MSTTPLSISRAKKYKTVFKGAAILTTFAALYIVTSPSTGKRLVKNASIKGLYNVSGNDCFLNCVLQSLASQESLLEILKLRCSSSTLYATLYELLQKLNSGPGNPITPGSFLNSLEIATNKKLVRSIQQDAQEFLQHLVETLELQKPHTYKWSKVLSFPVDSPFIGTMEQKVQCCQCLAISISYSTATSIQLCLPPEYSGNSNVSLLSLMEADREQHISDYKCDSCFKSSPKHSKTSCIRTVDWKNPPTILQIQLERTSYTCQGLTRNNVSISFPSKLILKNKHHYILRSLITHSGSVTYGHYLCYRLQDDIWWKANDSLITKSSLNEALSQTRSACLLFYEMESPLALD
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 11, Deubiquitinating enzyme 11, Ubiquitin thioesterase 11, Ubiquitin-specific-processing protease 11.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
Protein: YBEY_STRPG
Sequence: MYIEMIDETGQVSQEIMEQTLDLLNFAAQKTGKEEKEMSVTFVTNERSHELNLEYRDTDRPTDVISLEYKPETPILFSQEDLAADPSLAEMMAEFDAYIGELFISIDKAREQSQEYGHSFEREMGFLAVHGFLHINGYDHYTLEEEKEMFTLQEEILTAYGLTRQ
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NANR_ECOLC
Sequence: MGLMNAFDSQTEDSSPAIGRNLRSRPLARKKLSEMVEEELEQMIRRREFGEGEQLPSERELMAFFNVGRPSVREALAALKRKGLVQINNGERARVSRPSADTIIGELSGMAKDFLSHPGGIAHFEQLRLFFESSLVRYAAEHATDEQIDLLAKALEINSQSLDNNAAFIRSDVDFHRVLAEIPGNPIFMAIHVALLDWLIAARPTVTDQALHEHNNVSYQQHIAIVDAIRRHDPDEADRALQSHLNSVSATWHAFGQTTNKKK
What is the function of this protein?
Transcriptional repressor that controls expression of the genes required for the catabolism of sialic acids.
What are the official names of this protein?
HTH-type transcriptional repressor NanR.
What is the protein family that this protein belongs to?
Belongs to the NanR family.
Protein: YFB9_YEAST
Sequence: MIVELYSNIIEVRRYTTKDSLCSIFESGSTSHFEINQLQVKRLNLLQNQFASVFTSFHPKDNTKGIHINFFSPVTRITDLQYSFFYTNQILFGTRYLIKMIQNFVTGKVFTRTNQSK
What are the official names of this protein?
Uncharacterized protein YFL019C.
Protein: HYPF2_CUPNH
Sequence: MLMPRRPRNPRTVRIRIRVRGVVQGVGFRPFVYRLARELGLAGWVRNDGAGVDIEAQGSAAALVELRERLRRDAPPLARVDEIGEERCAAQVDADGFAILESSRSDAAVHTAIGHDTAVCPDCLAELFDPANRRYRYAFINCTQCGPRYTLTWALPYDRATTSMAPFPQCRPCLDEYNAPEHRRFHAEPNACPDCGPSLALLNAQGMPVEDVDPIAETVARLQRGEIVAIKGLGGFHLACDAHNADAVARLRSRKQREEKPFAVMVANLATAAQWGDIGSGEAALLTASERPIVLLRKRSGVDGRFAGVAPGLVWLGVMLPYTPLQYLLFHEAAGRPEGLGWLAQPQSLVLVMTSANPGGEPLVTGNDEAAQRLTGIADAFLLHDREILVRCDDSVVRGDGEPAPHVQFIRRARGYTPRAIKLARSGPSVLALGGSFKNTVCLTRGDEAFVSQHVGDLGNAATCEALIEAVAHLQRVLEIRPQLVAHDLHPDFFSTRHAAELAAQWGVPAVAVQHHHAHIAAVLAEHGSDEPAIGLALDGVGLGDDGQAWGGELLLVDGGACKRLGHLRELPLPGGDRAAREPWRMAAAALHAMGRGEEIEGRFPRQPGAPMVNRMLAQRLNAPLSSSMGRWFDAAAGLLGTRETMAYEGQAAMLLEGLAESWGEQPSPGRPKTVAHSLGGVPRSGGGTYKALALPDAWRIDAGNTLDLLPLLEALSAETNAARGAAQFHATLVAALEAWTVATVQVTGVRTVVFGGGCFLNHILARNLCRRLAARGLTVLTARQLPPNDGGIALGQVWVALQRAPN
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases.  HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
What are the official names of this protein?
Carbamoyltransferase HypF2, Carbamoyl phosphate-converting enzyme hypF2, [NiFe]-hydrogenase maturation factor hypF2, Hydrogenase maturation protein hypF2.
What is the protein family that this protein belongs to?
Belongs to the carbamoyltransferase HypF family.
Protein: MOAC_HELPY
Sequence: MPLTHLNEENQPKMVDIGDKETTERIALASGRISMNKEAYDAIINHCVKKGPVLQTAIIAGIMGAKKTSELIPMCHPIMLNGVDIDILEEKETCSFKLYARVKTQAKTGVEMEALMSVSIGLLTIYDMVKAIDKSMTISGVMLEHKSGGKSGDYNAKK
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: MAP1_SALTY
Sequence: MAISIKTSEDIEKMRVAGRLAAEVLEMIEPYIKPGVTTGELDRICNDYIVNEQHAISACLGYHGYPKSVCISINEVVCHGIPDDAKHLKDGDIVNIDVTVIKDEFHGDTSKMFIVGKPTILGERLCRVTQESLYLGIKMVKPGIRLRTIGAAIQKYAEGEGFSVVREYCGHGIGRGFHEEPQVLHYDADDGGVVLQPGMTFTIEPMLNAGDYRIRTMKDGWTVKTKDRSLSAQYEHTIVVTENGCEILTLRKDDTIPAIITHDE
What is the function of this protein?
Removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).  Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.
What are the official names of this protein?
Methionine aminopeptidase, MAP, MetAP, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
Protein: URE3_ACIB5
Sequence: MELNPTEKDKLLIFTAGLVAERRKARGLKLNYPEAVAFISAALLEGARDGMTVSELMHFGTTLLKREDVMDGVPEMIAEVQVEATFPDGSKLVTVHQPIV
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.