PharMolix/UniProtQA huggingface dataset:
Protein: AQP6_RAT
Sequence: MEPGLCNRAYLLVGGLWTAISKALFAEFLATGLYVFFGVGSVLPWPVALPSVLQVAITFNLATATAVQISWKTSGAHANPAVTLAYLVGSHISLPRAVAYIAAQLAGATVGAALLYGVTPGGVRETLGVNVVHNSTSTGQAVAVELVLTLQLVLCVFASMDSRQTLGSPAAMIGTSVALGHLIGIYFTGCSMNPARSFGPAVIVGKFAVHWIFWVGPLTGAVLASLIYNFILFPDTKTVAQRLAILVGTTKVEKVVDLEPQKKESQTNSEDTEVSV
What is the function of this protein?
Forms a water-specific channel that participates in distinct physiological functions such as glomerular filtration, tubular endocytosis and acid-base metabolism.
What are the official names of this protein?
Aquaporin-6, AQP-6.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Protein: MO25_DROME
Sequence: MPLFGKSQKSPVELVKSLKEAINALEAGDRKVEKAQEDVSKNLVSIKNMLYGSSDAEPPADYVVAQLSQELYNSNLLLLLIQNLHRIDFEGKKHVALIFNNVLRRQIGTRSPTVEYICTKPEILFTLMAGYEDAHPEIALNSGTMLRECARYEALAKIMLHSDEFFKFFRYVEVSTFDIASDAFSTFKELLTRHKLLCAEFLDANYDKFFSQHYQRLLNSENYVTRRQSLKLLGELLLDRHNFTVMTRYISEPENLKLMMNMLKEKSRNIQFEAFHVFKVFVANPNKPKPILDILLRNQTKLVDFLTNFHTDRSEDEQFNDEKAYLIKQIKELKPLPEA
What are the official names of this protein?
Protein Mo25, dMo25.
What is the protein family that this protein belongs to?
Belongs to the Mo25 family.
Protein: SURE_CLOB1
Sequence: MNILLTNDDGIEAEGINTLAELLSKYHDVIMVAPENQRSASSHSITIYEPIIVKQVKKPYNIEAYSISGTPADCVRVALDKLVPDNIDMVISGINKGLNIGNDILYSGTVSAAIEGAMYKVPSMAVSAQFIKNKKENYKIAAKYALRMLNRLKKEDLKNDVVLNLNIPFCSEEEIKGIKVCKVGNKIFNTRFSEEIDEEGNKVLKLEGDINKDIYEGTDVYYIRNKYVTLTPLHYDLTNFNILEETEQLFLS
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LGT_NEIG1
Sequence: MIIHHQFDPVLISIGPLAVRWYALSYILGFILFTFLGRRRIAQGLSVFTKESLDDFLTWGILGVILGGRLGYVLFYKFSDYLAHPLDIFKVWEGGMSFHGGFLGVVIAIWLFSRKHGIGFLKLMDTVAPLVPLGLASGRIGNFINGELWGRITDINAFWAMGFPQAHYEDAEAAAHNPLWAEWLQQYGMLPRHPSQLYQFALEGICLFAVVWLFSKKPRPTGQTAALFLGGYGVFRFIAEFARQPDDYLGLLTLGLSMGQWLSVPMIVLGIVGFVRFGMKKQH
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LEPA_UREU1
Sequence: MDKKFIRNFSIIAHIDHGKSTLSDRIIEFTNTLSKREMTNQILDSMDIERERGITIKLNAVQIKYHARDNNEYLIHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLSNVYLALENNLEIVPTINKIDLPSADPERVKKEIEDVIGLDTSDIPLISAKTGLNIQDVLEAIIKHVPPPLDANDDAKLQALIFDSFYDSYKGVVCLVRIKQGTIKVGDKIRMMANNKDYIVSELGIRTPKIVNKTELVAGEVGWVAAAIKTVKDINVGDTITHANNPADKPLPGYKKILPMVYCGLYPIDTSQYDDLKEAMAKISLSDAALTYEYETSQALGFGIRCGFLGLLHMDVIRERIAREFNIELILTAPSVIYKIELTNNQEISIDSPAKMPEPTNIKAIKEPFVKLAIITPDNYVGAIMELCQSRRGSYQDLEVIDGTRRRLIYKMPLAEIMYSFFDSLKSITKGYATMDYELIGYQAEKLVKIDIMLNGNKVDALSIIAHRDFAYGKSKIICERLKEVIPKHQFEIPIQASIGSKIIARETIKAVRKDVIAKCYGGDVSRKKKLLEQQKEGKKRLKAIGNVDVPQDAFVKVLSEN
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: AROA_GEOKA
Sequence: MQLPTNVSSLRGMIEVPGDKSISHRAVMLGALASGRTVIDHFLPGADCLSTIDCFRKLGVDIRQDGTTVVVEGAGPGGLREPAAVLDVGNSGTTARLLLGILAGQPFHACLVGDESIAKRPMGRVTKPLREMGARIDGREGGNYTPLSIRGGALRPLRYTSPVASAQVKSAILLAGLFADGVTSVAEPHRSRDHTERMVRLFGGEVNVDGLTVSVAGPQRLRGTHIYVPGDISSAAFFLVAGAIVPNSEITLKNVGLNPTRTGIIDVLTQMGADIAIDNVRNEETEPVGDITVRTSTLRAVEIGGDLIPRLIDEIPIIALLATQAEGTTVIKDASELKVKETNRIHTVVTELKKLGADIEATDDGMMIRGKTPLYADGIVVDSHGDHRIGMMLAVAACIAKGTVRLERSEAVAVSYPAFFADLRSLL
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KHSE_BUCAI
Sequence: MIKIYAPASIGNVGVGFDILGAAIIPVNGSLLGDFVTVKLSNKFNLVNKGIFSNKLPKNTEQNIVWKCWLKFCNTIKRNIPVSIILEKNMPIGSGLGSSACSIVATLVAMNEFCDKPLNSKELLLLMGEVEGEISGSIHYDNVAPCYLGGLQLILEDSKIISQTIPNFKNWFWIVAWPGTKVPTAEARDILPKKYKKETCIKNSRYLAGFIHASYSQQPHLAARLMQDFIAEPYRIKLLPNYLYVKEKIKKIGAISSGISGSGPTIFSISDNINTAQKISAWLTENYLQNTTGFVHICFLDSKGVRKIG
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLME_RHOPT
Sequence: MAKDTTGRMRVTVKSGGRMKLSSKLWLERQLNDPYVAQAKRDGYRSRAAYKLTEIDDKFRLLKSGMAVVDLGAAPGGWSQVAAKKVGAADGRGKVVAIDLLEMGEVPGVTFAQLDFLDPSAPERLREMLGGGADIVMSDMAANTTGHRKTDQLRIVGLVETAAMFASEVLKPGGTFLAKVFQSGADASLMTELKRDYASVKHVKPAASRKDSSERYLLATGFRGGAARDAEAAAEAE
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHL1_ARATH
Sequence: MVRASSSKKGGSKGGDKDDAESKQRKRLKTLALDNQLLSDSPAKSHSSLKPSKQVLKHHGTDIIRKSQRKNRFLFSFPGLLAPISAATIGDLDRLSTKNPVLYLNFPQGRMKLFGTILYPKNRYLTLQFSRGGKNVLCDDYFDNMIVFSESWWIGTKEENPEEARLDFPKELAQAENTEFDFQGGAGGAASVKKLASPEIGSQPTETDSPEVDNEDVLSEDGEFLDDKIQVTPPVQLTPPVQVTPVRQSQRNSGKKFNFAETSSEASSGESEGNTSDEDEKPLLEPESSTRSREESQDGNGITASASKLPEELPAKREKLKSKDSKLVQATLSNLFKKAEEKTAGTSKAKSSSKA
What is the function of this protein?
Component of the DNA topoisomerase VI complex involved in chromatin organization and progression of endoreduplication cycles.  Binds to DNA.  Required for endoreduplication beyond 8C.
What are the official names of this protein?
DNA-binding protein RHL1, Protein ELONGATED HYPOCOTYL 7, Protein ROOT HAIRLESS 1.
Protein: XYLF_SULAC
Sequence: MAKSKDEIKEEIAKAIINQVSKTDLSRRRALSTLAKGGIIAGVLAAFGAGFGSGYVTAPKGSSSSGVAPPQPGFMYGQVPEHPTWKIVFINHVTTNPFFVPTQYGIQDACLLLDCNYQWTGSETSDTTTMVNDMEAAISQGANGIAVSVISPNAFDKPTQDALNAGIPVFAYNAYIPTDDPSYSQYHNPPYLGYIGQSLYASGQLFGQRILNLVPSGSRVALFIATPGTANIQPRIDGIQSVIEGHYTIDVVATGALVSDEQSAIESYFNSHPDVKGMFAVDAGSTQGVGNVLREHGIKTVSNGGTIAAGGYDLLPATIQNIVDGYLDFTIDQQPYLQGFLPTLAIYLYLISDTLVYPLNIDTGSKFITNSNIQPYLLASRYEGSSTAYKPTSTTSSSSSSG
What is the function of this protein?
Part of the ABC transporter complex XylFGH involved in the uptake of xylose and arabinose.
What are the official names of this protein?
Xylose/arabinose-binding protein XylF, D-xylose/L-arabinose substrate binding protein, SBP.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 2 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: CRCB2_STAAN
Sequence: MISIILVMIGGGFGAIARSAITDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISWFPAFFVTGFLGGLTTFSTLAKELTLMMTPKFDINLFLNYSLLQFIIGFIACYIGYHI
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 2.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NCAP_I76A7
Sequence: MASQGTKRSYEQMETGGERQDATEIRASVGRMIGGIGRFYIQMCTELKLSDYEGRLIQNSITIERMVLSAFDERRNKYLEEHPSAGKDPKKTGGPIYKRIDGKWMRELILYDKEEIRRVWRQANNGEDATAGLTHIMIWHSNLNDATYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTIAMELIGMIKRGINDRNFWRGENGRRTRIAYERMCNILKGKFQTAAQRAMMDQVRESRNPGNAEIEDLIFLARSALILRGSVAHKSCLPACVYGLAVASGHDFEREGYSLVGIDPFKLLQNSQVFSLIRPNENPAHKSQLVWMACHSAAFEDLRVSGFIRGKKVVPRGRLSTRGVQIASNENVEAMDSSTLELRSRYWAIRTRSGGNTNQQKASADQISVQPTFSVQRNLPFERATVMAAFIGDNEGRTSDMRTEIIRMMESAKPEDLSFQGRGVFELSDEKATNPIVPSFDMNNEGSYFFGDNAEEYDN
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: PYL7_ARATH
Sequence: MEMIGGDDTDTEMYGALVTAQSLRLRHLHHCRENQCTSVLVKYIQAPVHLVWSLVRRFDQPQKYKPFISRCTVNGDPEIGCLREVNVKSGLPATTSTERLEQLDDEEHILGINIIGGDHRLKNYSSILTVHPEMIDGRSGTMVMESFVVDVPQGNTKDDTCYFVESLIKCNLKSLACVSERLAAQDITNSIATFCNASNGYREKNHTETNL
What is the function of this protein?
Receptor for abscisic acid (ABA) required for ABA-mediated responses such as stomatal closure and germination inhibition.  Inhibits the activity of group-A protein phosphatases type 2C (PP2Cs) when activated by ABA.
What are the official names of this protein?
Abscisic acid receptor PYL7, ABI1-binding protein 7, PYR1-like protein 7, Regulatory components of ABA receptor 2.
What is the protein family that this protein belongs to?
Belongs to the PYR/PYL/RCAR abscisic acid intracellular receptor family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell membrane. Note=Localizes at the plasma membrane in the presence of a CAR protein.
Protein: DLPC_DICDI
Sequence: MSHQQQQAHFDISSNSTLTTNTIATTTNASVSSSPQLNKAQMAIAEAMALKMHEEEKKKREEKKRKRDNEELLSKQVRTKLENERKKLDDSESINASTNQELYSLFNDLQMISHDHNISFDTPELVVVGMQSDGKSSFIESLLGFQFNIVETNIGTRRPLIIQMINNPSKQQPSCRFKKEDYSNSYGGSSSSTSTTSGNSNHNTDKQQNVSSSQGGGGGSNNLNEDKWEEYETPVNELTEEIIRRTNERTGRAGDRVSSIPIFLRVEFAHCSNLNIYDTPGFRKGGDERLKYEISEMVKKLIEPKNRIIVCLEQSNVEWANTISRPLVKKIDPDFSRTILVNTKFDNRVKELRNRESAHKYLEGEGIIAQKKPFFISLPLKRNLETHRFKDAMKETFLDDYRKLLEIGFDENRFGGQIGIYKVRQYVENLLHEKYQQNLLPSMLQLESICKKTEADIVRVKKELSDNNIVTLKEKVMRFVSNFNGQIERLLEGSVVGDPDEFGQTLLQEKENCSVQPWPGYNFDFDIQNSNYSLYGGAQYERLLNEFEFVIHSKEFPETSINEVASAIGVSKSHNSPIYELAATNIFQTKSKKVLLPLIDIVLQRSSYIMKRLFDISVSILGKDENESSHTVSLYEHFLKELQSQYEKFIQTIESECKSRLKDDFEMFTKIVDWNLLSGLTEIKPYNYLKVSPEETKQRVISIMDCKKLEDEPLSRSRNIDDDTYQKVCMIAGRLFSGIRFFFSKLIRNKLNAFFLDPMFQKLGSFVTDYFSKLNDQKYEEMFQLGLKELENKLHKLEFQLIDCKKNRDKFKDVYNRMKQSLNQNQNQNSSSSSNSASSSNNNVIIKHQQSLNGKFSTPDKNSLTMSPFTSPFTQSNYHQHNNNNYQINQQPLDINNDHYFDQN
What is the function of this protein?
Involved in cytokinesis.  May hydrolyze GTP.
What are the official names of this protein?
Dynamin-like protein C.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS21_BURL3
Sequence: MTIIRVKENEPFEVAMRRFKRTIEKNGLLTELRAREFYEKPTAERKRKKAAAVKRHYKRIRSQTLPKKLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: Y1441_METTH
Sequence: MVGLVFVGMDHGTTGVSFTILGDDAEHFKIGREDLSTGRASALDELKDRVPLNEIDLMAITYAMGDAISTIKPIERVKNRGIISIGGAGKVTGGGTAVYSEIESSGIPTLLIPGLHRNTPCLDERFRAAYSHHASPEKVSICYNAYLETGWENMIVSDISSNTVTMLIQDGRIVGAMDACVGAMGVIHGPLDLEMLRKIDDGEKTANECFSHAGAVKIAGIDTKVSRAREELLEMYRAGRDEARLALDTMMMTIAMEIWGLAGISSGIDGIVLTGSVGAMREPYDFHGKLKDMVKEIADVRCTDSHLRLHGKCQIARDIYNGKREILGIEVEV
What are the official names of this protein?
UPF0285 protein MTH_1441.
What is the protein family that this protein belongs to?
Belongs to the UPF0285 family.
Protein: RHG42_MOUSE
Sequence: MGLPTLEFSDSYLDSPDFRERLQCHEIELERTNKFIKELLKDGSLLIGALRNLSMAVQKFSQSLQDFQFECIGDAETDDEISIAQSLKEFARLLIAVEEERRRLIQNANDVLIAPLEKFRKEQIGAAKADSQIGREHQNFYEASLEYVFKIQEVQEKKKFEFVEPLLSFLQGLFTFYHEGYELAQEFAPYKQQLQFNLQNTRNNFESTRQEVERLMQRMKSANQDYRPPSQWTMEGYLYVQEKRPLGFTWTKHYCTYDKGSKMFTMSVSDVKASGKMNGLVTGSPEMFKLKSCIRRKTDSIDKRFCFDIEVVERHGIITLQAFSEANRKLWLEAMDGKEPIYTLPAIISKKEEMYLNEAGFNFVRKCIQAVEMRGITILGLYRIGGVNSKVQKLMNTTFSPKSPPDMDIDIELWDNKTITSGLKNYLRCLAEPLMTYKLHKDFIIAVKSDDQNYRVEAVHALVHKLPEKNREMLDILIKHLLKVSLHSQQNLMTISNLGVIFGPTLMRAQEETVAAMMNIKFQNIVVEILIEHYEKIFHTAPDPNIPLPQPQSRSGSRRTRAICLSTGSRKPRGRYTPCLAEPDSDSYSSSPDSTPMGSIESLSSHSSEQNSTTKSTACQPREKSGGIPWITTPSSSNGQKSQGLWTTSPESSSREDATKTDVESDCQSVASITIPGNVSPPIDLVKKGPYGLSGLKRSSASSSLRSISAAEGNKSYSGSIQSLTSIGSKESPKAIPNPELPPKMCRRLRLDTASSNGYQRPGSVVAAKAQLFENAGSPKPVSSGRQAQAMYSCKAEHSHELSFPQGAIFSNVHPSVEPGWLKATYEGRTGLVPENYVVFL
What is the function of this protein?
May influence blood pressure by functioning as a GTPase-activating protein for RHOA in vascular smooth muscle.
What are the official names of this protein?
Rho GTPase-activating protein 42, Rho-type GTPase-activating protein 42.
Protein: ENO_STAAR
Sequence: MPIITDVYAREVLDSRGNPTVEVEVLTESGAFGRALVPSGASTGEHEAVELRDGDKSRYLGKGVTKAVENVNEIIAPEIIEGEFSVLDQVSIDKMMIALDGTPNKGKLGANAILGVSIAVARAAADLLGQPLYKYLGGFNGKQLPVPMMNIVNGGSHSDAPIAFQEFMILPVGATTFKESLRWGTEIFHNLKSILSKRGLETAVGDEGGFAPKFEGTEDAVETIIQAIEAAGYKPGEEVFLGFDCASSEFYENGVYDYSKFEGEHGAKRTAAEQVDYLEQLVDKYPIITIEDGMDENDWDGWKQLTERIGDRVQLVGDDLFVTNTEILAKGIENGIGNSILIKVNQIGTLTETFDAIEMAQKAGYTAVVSHRSGETEDTTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDELFETAKYDGIKSFYNLDK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: CPG2_PORG3
Sequence: MKKNFSRIVSIVAFSSLLGGMAFAQPAERGRNPQVRLLSAEQSMSKVQFRMDNLQFTDVQTSKGVAQVPTFTEGVNISEKGTPILPILSRSLAVSETRAMKVEVVSSKFIEKKDVLIAPSKGVISRAENPDQIPYVYGQSYNEDKFFPGEIATLSDPFILRDVRGQVVNFAPLQYNPVTKTLRIYTEIVVAVSETAEAGQNTISLVKNSTFTGFEDIYKSVFMNYEATRYTPVEEKENGRMIVIVAKKYEGDIKDFVDWKNQRGLRTEVKVAEDIASPVTANAIQQFVKQEYEKEGNDLTYVLLVGDHKDIPAKITPGIKSDQVYGQIVGNDHYNEVFIGRFSCESKEDLKTQIDRTIHYERNITTEDKWLGQALCIASAEGGPSADNGESDIQHENVIANLLTQYGYTKIIKCYDPGVTPKNIIDAFNGGISLVNYTGHGSETAWGTSHFGTTHVKQLTNSNQLPFIFDVACVNGDFLFSMPCFAEALMRAQKDGKPTGTVAIIASTINQSWASPMRGQDEMNEILCEKHPNNIKRTFGGVTMNGMFAMVEKYKKDGEKMLDTWTVFGDPSLLVRTLVPTEMQVTAPANISASAQTFEVACDYNGAIATLSDDGDMVGTAIVKDGKAIIKLNESIADETNLTLTVVGYNKVTVIKDVKVEGTSIADVANDKPYTVAVSGKTITVESPAAGLTIFDMNGRRVATAKNRMVFEAQNGVYAVRIATEGKTYTEKVIVK
What is the function of this protein?
Thiol protease.  Acts synergistically with RgpA to catalyze the maturation of fimbrial subunits, such as FimA (PubMed:9786913).  Its proteolytic activity is a major factor in both periodontal tissue destruction and in evasion of host defense mechanisms (By similarity).
What are the official names of this protein?
Gingipain R2, Arg-gingipain.
What is the protein family that this protein belongs to?
Belongs to the peptidase C25 family.
What are the subcellular locations of this protein?
Secreted.
Protein: METK_BUCAT
Sequence: MTEYLFTSESVSEGHPDKIADQISDALLDEILKQDLKARVACETYVKTGMVLIGGEITTTAWVDVEEITRKTINDIGYVNSDAGFDANSCAVLSAIGKQSPDINQGINRFDPLKQGAGDQGIIFGYATNETEFFMPAPITYAHLLMQKQSELRKKNILPWLRPDAKSQVTFKYNNGNIIAIDTVVLSTQHQENITQKYLKEAVMDEIIKPVLPDKWLTKNTKFFINPTGRFVIGGPMGDCGVTGRKIIVDTYGGMSRHGGGAFSGKDPSKVDRSAAYAARYVAKNIVASGLAARCEIQLSYAIGIAEPISIMIDTFNTGKISNSALISLVRSIFDLRPYGLIKMLNLLQPIYLKTAVYGHFGRKEFPWENLDKVNELS
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_CARHZ
Sequence: MDLLKSLEEEQLRKDLPEFRPGDTVKVYFKVIEGNRERIQPYEGVVIRKRGSGLSATFTVRRVSYGIGVERTFPLHSPRIEKIEVIRRGKVRRARLYYLRKLTGKAARIAERR
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: PREB_HUMAN
Sequence: MGRRRAPELYRAPFPLYALQVDPSTGLLIAAGGGGAAKTGIKNGVHFLQLELINGRLSASLLHSHDTETRATMNLALAGDILAAGQDAHCQLLRFQAHQQQGNKAEKAGSKEQGPRQRKGAAPAEKKCGAETQHEGLELRVENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGRGPELLGSHETALFSVAVDSRCQLHLLPSRRSVPVWLLLLLCVGLIIVTILLLQSAFPGFL
What is the function of this protein?
Was first identified based on its probable role in the regulation of pituitary gene transcription.  Binds to the prolactin gene (PRL) promoter and seems to activate transcription.
What are the official names of this protein?
Prolactin regulatory element-binding protein, Mammalian guanine nucleotide exchange factor mSec12.
Protein: YACG_NEIMA
Sequence: MAESRQTRLQVKCPTCQTAVVWEPENAFRPFCSQRCKLIDLGGWADGKYTVSGQTESLPEISEPDMAYR
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: ACSA_BARHE
Sequence: MSEKIYPIPDNIKKNALIDEETYQQWYQESINDPESFWAKHGQCIEWFKPYTKVKNTSFNGDVSIQWYEDGITNVAYNCIDRHLKTHGDKIALIWEGDNPYHDKKITYNELYEHVCRFANILKNHGVKKGDKVTIYLTMIPEAAYAMLACARIGAIHSVIFAGFSPEAIAGRIVDCESTFIITANQGLRGGKQINLKDSVDHAIEIAARQNVHVDQVMVIRRTCGPIHWVEGRDFWYHEEVSHTKTDCPAEKMNAEDPLFILYTSGSTGKPKGVLHTTAGYLVYASMTHKYVFDYHAGEIYWCTADIGWITGHSYLVYGPLCNAATTLMFEGTPTFPDNGRFWEIVDKHQVNIFYTAPTAIRALMGAGNSFVERSKRTSLRLLGSVGEPINPEAWEWFYHTVGNNHCPILDTWWQTETGGHMITPLPGATPLKAGSATRPFFGVQLQIIDAEGNVLEGETEGNLCIIDSWPGQMRTLYNDHERFIQTYFSTYKGKYFTGDGCRRDSDGYYWITGRVDDILNVSGHRLGTAEIESALVSHPAVSEAAVVGYPHTIKGQGIYSFITLMEGTAPSEELHQELIRHVRKEIGSIAILDKVQFAPQLPKTRSGKIMRRILRKIAENNFDNLGDISTLSEPQVIDDLIANRQNREITA
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: Y6755_BRADU
Sequence: MPIHIIDRRLNPGGKSLENRQRFLRRAKSLVQGAVKKTSQERDIKDVLEGGEVTIPLDGMHEPRFRREGGTRDMVLPGNKKFVEGDYLQRSGQGSAKDSGPGEGDSEDAFRFVLSRDEFVDLFLDDLELPDLAKRKIAQTESEGIQRAGYTTSGSPANISVSRTVKLALARRIALKRPRKDEIEELEAAIAACTDEDERVVLLAELEKLMAKTKRIPFIDPLDIRYRRFETVPKPVAQAVMFCLMDVSGSMSEHMKDLAKRFYMLLYVFLKRRYKHVEIVFIRHTDRAEEVDEQTFFYGPASGGTLVSSALQAMHDIVRERFNPSDWNIYAAQASDGDNSYSDGELTGLLLTDKILPVCQFFAYLEVGESGGSAFDLSDSSLWTLYERLRNSGAPLSMRKVSERSEIFPVFHDLFQRRETSQEKAAP
What are the official names of this protein?
UPF0229 protein bll6755.
What is the protein family that this protein belongs to?
Belongs to the UPF0229 family.