PharMolix/UniProtQA huggingface dataset:
Protein: SYA_THEP1
Sequence: MRYMTSEEIREAFLKFFEKKGHKILPSASLIPDDPQLLFTVAGMVPFKPIFWGKVEPVYTRVATCQKCLRTVDIENVGKTPRHHTFFEMLGNFSFGDYFKEEAIEWAWEFLTQVLGVPEEKLWVSVYEEDEEAFRIWNEKIGLPEKKILRMGKEDNFWGPAGPTGPCGPDTEIFYDTGYSKGCPEGEECTPANSEGRFVEIWNLVFTEYYQDEEGKLHPLPRKNIDTGAGLERFCAMMQGVYSNFDTDLFQPIINRIEELTGVGYKTDEEKDVSIRVIADHMRAITFLISEGVFPSNEGRGYVLRRIIRRAMRHGILLGMSEPFLYRIVDAVAEKMGKVYPEIVRGESMVKEVLSAEESRFLKTLEQGMKVFDEIVEKKGRIDSEDAFKLYDTYGLPLELTLEIAREKGVEVDVKEFNKYMEEQQRKSRVALGDVEFARRYEYLEELPKDFRTEFTGYEKLEDEGEVVLIAKNEKAVEDATEDAVEVVFSKTPFYAEKGGQVSDTGTVEWEDGKALVEYVFEASEGVIVHRIKVLAGTLRRGQKVVLRVDKKRREATMRNHTATHLLHAALKKVLGDHVRQAGSLVAPDRLRFDFTHFKGLSMAEIEQVENLVNEWIMEAIPVEVRYTSYEEAVKSGVVALFTEKYGDVVRVVEVPGVSKELCGGTHVSNTGQIGLFKIISEESVSSGVRRIEAVTGFSTLELLRNQKKLIDQLKEILGAREDELTDRVLGLREKVKELEKKLSQGRISEEKIAMKQLEDGARVFYAVFEDVEAKHLGGIADNVLKKEREGIVILLSKFEDKVSLVVKVSENLLDKYDASSIARNIAKELGGSGGGRRNFAQAGGRHPEKIRGVLERLEEFLR
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1812_MYCTU
Sequence: MTRVVVIGSGFAGLWAALGAARRLDELAVLAGTVDVMVVSNKPFHDIRVRNYEADLSACRIPLGDVLGPAGVAHVTAEVTAIDADGRRVTTSTGASYSYDRLVLASGSHVVKPALPGLAEFGFDVDTYDGAVRLQQHLQGLAGGPLTSAAATVVVVGAGLTGIETACELPGRLHALFARGDGVTPRVVLIDHNPFVGSDMGLSARPVIEQALLDNGVETRTGVSVAAVSPGGVTLSSGERLAAATVVWCAGMRASRLTEQLPVARDRLGRLQVDDYLRVIGVPAMFAAGDVAAARMDDEHLSVMSCQHGRPMGRYAGCNVINDLFDQPLLALRIPWYVTVLDLGSAGAVYTEGWERKVVSQGAPAKTTKQSINTRRIYPPLNGSRADLLAAAAPRVQPRP
What are the official names of this protein?
NADH dehydrogenase-like protein Rv1812c.
What is the protein family that this protein belongs to?
Belongs to the NADH dehydrogenase family.
Protein: ATPD_METS4
Sequence: MAQNGSESGSTLGGVAGRYASALFELARDERAVDAVTEGLDRFDALLRESADLQRLVRSPVFSTEEQVKAVEAVLARAGITGLAANFIRLAAANRRLFVLPDMIRAYRVLVREAKGIVRAEVRLAEPPSDAVLEEIKASLRDVARAEVELDLRVDPSLIGGIVVKLGSRMVDASLRTRLNSIRLAMRDAR
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GMM_SALTY
Sequence: MFLRQEDFAAVVRATPLISLDFIVENGQGEILLGQRLNRPAQGYWFVPGGRVCKDETLEAAFARLTQAELGVRLPLAAGTFYGVWQHFYDDNFSGEDFSTHYIVLGFRLRVAESDLRLPDAQHGSYRWLTPEQLLASDNVHENSRAYFSPDAPAVGL
What is the function of this protein?
Hydrolyzes GDP-mannose.
What are the official names of this protein?
GDP-mannose mannosyl hydrolase, GDPMH.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
Protein: TRIM9_BOVIN
Sequence: MEEMEEELKCPVCGSFYREPIILPCSHNICQACARNILVQTPESESPQSRRASGSGVSDYDYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPATHLSPALASVPRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAALKCQLCEKAPKEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSPRKVSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDFDLSLDNSPLLQSIHQLDFVQMKASSPVPATPILQLEDCCTHNNSATLSWKQPPLSTVPAEGYILELDDGNGGQFREVYVGKETMCTVDGLHFNSTYNARIKAFNKTGVSQYSKTLVLQTSEVAWFAFDPGSAHSDIIFSNDNLTVTCSSYDDRVVLGKTGFSKGVHYWELTVDRYDNHPDPAFGVARIDVMKDVMLGKDDKAWAMYVDNNRSWFMHNNSHTNRTEGGITKGATIGVLLDFNRKTLTFFINDEQQGPIAFENVEGLFFPAVSLNRNVQVTLHTGLQVPDFYSSRASIA
What is the function of this protein?
E3 ubiquitin-protein ligase which ubiquitinates itself in cooperation with an E2 enzyme UBE2D2/UBC4 and serves as a targeting signal for proteasomal degradation.  May play a role in regulation of neuronal functions.  May act as a regulator of synaptic vesicle exocytosis by controlling the availability of SNAP25 for the SNARE complex formation.
What are the official names of this protein?
E3 ubiquitin-protein ligase TRIM9, RING-type E3 ubiquitin transferase TRIM9, Tripartite motif-containing protein 9.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, dendrite. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Synapse. Cytoplasm, cytoskeleton. Note=Enriched at synaptic terminals where it exists in a soluble form and a synaptic vesicle-associated form. Associated with the cytoskeleton (By similarity). Found in proximal dendrites of pyramidal neurons in the cerebral cortex and hippocampus, and Purkinje cells in the cerebellum (By similarity).
Protein: PYRB_RHOP2
Sequence: MTPALKSTFVLAHRHLLGIEGLSAADITGLLDLSEEYVELNRQVDKKRASLRGRTQVNLFFEASTRTQSSFEIAGKRLGADVMNMSVSSSSMRKGETLMDTAVTLNAMHPDILVVRHHASGAVELLARKVDGSVINAGDGAHEHPTQALLDALTIRRNKGRLEGLVVAICGDVMHSRVARSNILLLNTMGARVRVVAPSTLLPRGIERMGVEVARDMREGLDGADIVMMLRLQRERMNGSFVPSSGEYFHYFGLDQKKLAYAKPDALVMHPGPMNRGVEIDSIVADGAQSVIREQVEMGVAVRMAVLEALARNLPNA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: SNU13_SCHPO
Sequence: MSVNPKAFPLADSGLTQQILDLVQQASHYKQLRKGANEATKTLNRGISEFIVMAADTEPIEILLHLPLLCEDKNVPYVFVPSKAALGRACGVSRPVISASITTNEASDLLPQIQAIKLAIEKLLI
What is the function of this protein?
Common component of the spliceosome and rRNA processing machinery.  In association with the spliceosomal U4/U6. U5 tri-snRNP particle, required for splicing of pre-mRNA.  In association with box C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and site-specific 2'-O-methylation of substrate RNAs.  Essential for the accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs (By similarity).
What are the official names of this protein?
13 kDa ribonucleoprotein-associated protein.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: NU6C_SOLTU
Sequence: MDLSEPIHDFLLVFLGSGLILGGLGVVLLPNPIYSAFSLGLVLICTSLFYILSNSYFVAAAQLLIYVGAINVLIIFAVMFMNGSEYYKDFHLWTVGDGITSMVCISLFISLITTISDTSWYGIIWTTRSNQIIEQDFLSNSQQIGIHLSTDFFLPFELISIILLVALIGAIAVARQ
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 6, chloroplastic, NAD(P)H dehydrogenase subunit 6, NADH-plastoquinone oxidoreductase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: SELO_GLOVI
Sequence: MEGGLDTDASVHNNPLLQLDYEPAFASLGDDYYDLVAAAPFPEHRLRFRGDGVLRLLGLDPATVGEEHFIEAFGRFAGRGPFLAMRYHGYQFGEYNPYLGDGRGFLYGQVRGLDGELYDFGTKGSGTTPYSRGGDGRLTLKGGVREVLASEALHHLGVRTSRSLSLIETGEALWRGDEPSPTRSAVLVRTSRSHVRFGTFERLHHFKRKDLIQKLLDYVIAVYYPHYGAEPERYALFYRELVGRTAELAAQWMAVGFTHAVLNTDNMSITAESFDYGPYAFIDRFDPGFTAAYFDHYGRYSYGNQPLVCRINLEALQLPLSMVIPIADLEAGLAIFDTHYAAHYTARMLAKLGFGALGPVLGPELVKATLNYLEAAQAGYHGFFQALAASFDRSWQSDQGAIPAPVVGAPEAFELWRESYFRALASLSDSELLRVGERLNRHNPTTVLLRPAIEAVWAAIDQNDDWQPFYDLIGRLRKPYAIA
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: NUF2_YEAST
Sequence: MSRNQDVFPILDLQELVICLQSCDFALATQENISRPTSDYMVTLYKQIIENFMGISVESLLNSSNQETGDGHLQEENENIYLDTLNVLVLNKICFKFFENIGVQDFNMTDLYKPEAQRTQRLLSAVVNYARFREERMFDCNSFILQMESLLGQLRSKFDDYNLIQQQLKQYEDVDGDNIPDEQELQKLEEQNKELEIQLKKLTKIQETLSIDYNDYKISKQSIFKDLEALSFQIVELESNRDKLIKISNTDMEELSEGIKELNDLLIQRKKTLDDLTAQQKNLQDTVTTFETIISELYDVLRIISSEVQESNRTETELVGLKQNLINNKLKLMNVLETGIMYKLEILQEQLDLQLKNLEKLSQDTKEESRLNDTKLMDLQIKYENEIKPKIDKTDIFIQEELISGKINKLNDEIKQLQKDFEVEVKEIEIEYSLLSGHINKYMNEMLEYMQ
What is the function of this protein?
Acts as component of the essential kinetochore-associated NDC80 complex, which is involved in chromosome segregation and spindle checkpoint activity.
What are the official names of this protein?
Kinetochore protein NUF2.
What is the protein family that this protein belongs to?
Belongs to the NUF2 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with kinetochores.
Protein: TGRM2_MOUSE
Sequence: MDTRDDVTLAKVPAPVAVYCGSVPRTSVGLRAPPPGGIDSSLLAHDEASLQPVSSVLPSSEKPSQLSREHEDQSSLMLNAPLKGWQARNGYPRGLGVLPLGHHLGAAIPSLESEASSVARDTIQIKDKLKKRRLSEGMAASSQASLDPVGGPRGVPLRSTIPRTTSQRLLRVPRPMPPIQSIPTTPEANSAKEKDLDPPGGRQDLQDPGASAQEVQISRQYLHCADEKMHKSLGGLVIPPIPKARMPTGTSSCRPGSLPSPLCPSQDVLMGPKAPHTRLTCENGPLEKTPKSPASKPLVPVVKAKSAEAPETSLASSQSTFTLTAFSSHAKETRSLENEEDQKESSTKVQVTISKSAQEKMRLKQMKEMELLRRAKEPEWERELVSQGLGTRRTSAKEGLLPLRGSGALSEPAGMSSPRRNNMGALQRKRANRASLPSIPVSKQEPGFARHASANSLPAVLTLGSPEWEEEEEEMDLRALRELRPFSNPELGLTDALQCLNSNDWQMKEKGLVNIQRLAACHSEVLGTRLHDVSLAVTAEVTNLRSKVSRLAISTLGDLFRVLKKNMDQEAEEIVRCLLQKMGNTSEFIQRAANRALGAMVENVTPARALVALTSAGVYHRNPLVRKCTAKHLSAVLEQIGAEKLLSGSRDNTDMLVHNLVRLAQDSNQDTRFYGRKMVNILMANAKFDAFLKQSLPSHDLRKVMAAIKQRGIQDNHELQSAKGRKVSKSLVVCENGLPSHEGVETSEQLRELTRLLEAKEFQARMEGVGKLLEYCKAKPELVAANLVQVFDVFTPRLHDSNKKVNQWALESLAQMLPILKESIHPMLLSLIIAAADNLNSKNSGISTAASTVLDAMMGSLDHLCLLQAFAGRVRFLTGPAVLDITDRLSVLVASVYPRKPQAVERHILPVLWYFLNKMSGNGVLPGRGGNVRTAVCRLARSLQEQMGSRLQDFAASQPQQVLKALQGLLASESLGANDKVIGGRMAPDIQMTGTTCPQQLD
What are the official names of this protein?
TOG array regulator of axonemal microtubules protein 2, Crescerin-2, Protein FAM179A.
What is the protein family that this protein belongs to?
Belongs to the Crescerin family.
Protein: PYRD_PHOLL
Sequence: MCYPLARKALFQLDPEHAHELTFRQLKRITGTPFEFFIRQSIATKPVTCMGLSFKNPLGLAAGLDKDGDCIDAFGAMGFGFIEIGTVTPRAQAGNDKPRLFRIVEAEGLINRMGFNNLGVDNLVENVKKAKYGGVIGINIGKNKDTPVEHGKDDYLICMDKIYPHAGYITINISSPNTPGLRTLQYGEALDDLLSAIKNKQGELQQKYQKYVPVAVKIAPDLSEEELIQIADSLIRHNIDGAIATNTTLDKRLVEGLNYCQQAGGLSGRPVQLRSTEVIRQLSQELRDKIPIIGVGGIDSLTAAREKIAAGASLIQIFSGFIYHGPKLIKDIVNHI
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: APNO_CUPNN
Sequence: MKEKIALFGAGGKMGVRLAKNLLKSDYRVSHVEVSEVGKKRLKDELGLECVSTEAALDNVDVVILAVPDTIIGKIAAQIAPQLRPGTMVMTLDAAAPFAGHLPDRPDLTYFVAHPCHPLIFNDETDPEARRDYFGGGAAKQSITSALMQGPEEAFDLGEAVAKVIYAPILRSYRLTVDQMALLEPGLSETICATLLQVMREAMDETVRRGVPKEAARDFLLGHMNILGAVIFNEIPGAFSDACNKAIEFGKPRLMRDDWIKVFDREEIAESIRRIT
What is the function of this protein?
Involved in catabolism of D-apiose.  Catalyzes the conversion of D-apionate to 3-oxo-isoapionate.
What are the official names of this protein?
D-apionate oxidoisomerase.
What is the protein family that this protein belongs to?
Belongs to the ApnO family.
Protein: COX17_SCHPO
Sequence: MSSSTEPSTATKVSEPAPIASEEKPKPCCACPETKQARDACMLQSSNGPIECAKLIEAHKKCMAQYGYEV
What is the function of this protein?
Copper chaperone for cytochrome c oxidase (COX).  Binds two copper ions and deliver them to the Cu(A) site of COX (By similarity).
What are the official names of this protein?
Cytochrome c oxidase copper chaperone.
What is the protein family that this protein belongs to?
Belongs to the COX17 family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space.
Protein: CHLE_USTMD
Sequence: MRLPNLTLLVWAATSVGLVSALPQVSYKADATASAPTVKLHQGTVRGLADDNYGLEQFFGIPYAKPPVGSLRFAKPQPLGPASSHKTVIDATRFGDICMQTVAPSPLYNMSEDCLNLNVVRPKGTTAKDKLPVLVWIYGGAFRQGSTPIYNASELVQKSVEIGKPIVFVAISYRVGPFGFIGGSEIADSDSATSNAGLYDQRLGLKWIRHNIGKFGGDKNRVTLFGQSAGAMSIALQNFAYDGNNHGLWHAAIMNSGGIAPGPLLTPKHPTVEQSFKRLANGVGCTGGSLLRCLRKANASEVQTVASNLTAQAGGTFPIPGALAWLPLVDYELITNYPSVNLPQGKLADIPVIQGNALDEGTSFAQKQLNSSADFERWVRSAAVIHNTSYTEQALQKVFELYPDVPEQGSPFYNAETATSAATTSDLNSRQYPPLTSNQYKRSAAFFGDFTFQAQRRTYLKAATLGWKKNKAKVWSYEFQQNDKFANGTGSLLGPYHGADVKYYFIRPDGRQKDPVLADRMPRAYISFVYHHDPTVLGGFEWPPYGKGKKLLQMKGDNTTVIEDAYRKEAMDALTNRKAAKVFGF
What is the function of this protein?
Extracellular chlorogenic acid esterase that displays a surprisingly broad substrate profile (Ref. 1).  The enzyme's unique properties may contribute to the specific environmental interaction between the pathogenic fungus and its host, Zea mays (Ref. 1).  Additionally, the release of caffeic, p-coumaric, and ferulic acids from agroindustrial by-products such as destarched wheat bran (DSWB) and coffee pulp (CP) renders this enzyme an attractive candidate for the generation of natural aroma precursors and antioxidants (Ref. 1).
What are the official names of this protein?
Chlorogenic acid esterase.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS5_XANP2
Sequence: MAREREQRHEREDRDNTFVDKLVHINRVAKVVKGGRRFGFAALVVVGDQKGRVGFGHGKAREVPEAIRKATESAKRALIRVPLREGRTLHHDVHGHHGAGKVILRAAPAGTGIIAGGPMRAVFETLGMHDVVAKSFGSSNPYNMVRATFDALKNQDSPRSVAARRGIKVSQLQSRRRVEDAEATD
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: COA3_LACTC
Sequence: MAFEPSRYQDPRTWKMTPAMIRARRPFFKKNLLGLGILVSVTGGIYVYTHRFLNRDNDFADVPIPPIDPKELEQLKKEYEQHKRDVAARDE
What is the function of this protein?
Required for assembly of cytochrome c oxidase (complex IV).
What are the official names of this protein?
Cytochrome c oxidase assembly factor 3, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the COA3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: RL7A_METAR
Sequence: MAKPTYVKMDFPQELQDKALEALELARDTGKIRKGTNEVTKAIERGVAQLVIVGEDVTPEEIVAHIPALSDEKKIPYVFVKKQQELGAASGLEVGCATSAIVDAGKAKALVDEITQKFSALKA
What is the function of this protein?
Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
What are the official names of this protein?
50S ribosomal protein L7Ae, Ribosomal protein L8e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPH11_ARATH
Sequence: MNCFSFSFIIIVLCAGSSNAKFREKNSVVFKNSLGVKNVLKIHCTSKDDDLGYHYLRPGVQIYEFRFHDSVLKTKFDCELWQGRGPTYKFYANFRAYKSGGLIAHYGKKNIWEAREDGIYFTHGKEIPKLEYKWSPIGKPPSP
What are the official names of this protein?
S-protein homolog 11.
What is the protein family that this protein belongs to?
Belongs to the plant self-incompatibility (S1) protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS1_SYNR3
Sequence: MLTVALPKGALLKDSVARFAAAGLDFSAITAADNRQLMLPSACGRARALLVRNGDVPVYVAYGQAQLGVVGYDVLKEQQRTVAQLLDLGFGGCRMAVAVKESSPYRRASDLPAHCRVASKFTSSAQEFFNQLDLPVELIHLTGSVELGPITGISEAIVDLVATGRTLRDNGLIAIEDLFHSTARLIGNPLALRLDTGELNELVQAMEGQGVTP
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBBP4_CHICK
Sequence: MADKEAAFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKDFSIHRLVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIKINHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENINNDEDPEGSVDPEGQGS
What is the function of this protein?
Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA.  Component of several complexes which regulate chromatin metabolism.
What are the official names of this protein?
Histone-binding protein RBBP4, Chromatin assembly factor 1 subunit C, CAF-1 subunit C, Chromatin assembly factor I p48 subunit, CAF-I 48 kDa subunit, CAF-I p48, chCAF-1 p48, Retinoblastoma-binding protein 4, RBBP-4, Retinoblastoma-binding protein p48.
What is the protein family that this protein belongs to?
Belongs to the WD repeat RBAP46/RBAP48/MSI1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: AVEN_MOUSE
Sequence: MQAERGARGGRGRRGGRERPGGDREPVGAATALARGGCGDGGGRRGRGRGFRRGRGGGGLRGGRWEPGGRGGGASTRVEEDSDSETYGEENDEQGNFSRRKIVSNWDRYQDTEKEVNGESGESQRGTDFSVLLSSAGDSFSQFRFAEEKEWDGETSCPKQNSALYVDSESLVRALEQLPLAVRLNVASELIQTTIPLELPQVKPRRNDDGKELGMHLRGPISELRSAAGACPRSLGRGSLRQSPLEGLQKAPTPTQSVADHLEEELDMLLHLDAPVQEEGNISPDQTSRDQEPEKDGQVAQEETGPEKPSVTREKNVEPEQPSTSKNVTEEELEDWLDSMIS
What is the function of this protein?
Protects against apoptosis mediated by Apaf-1.
What are the official names of this protein?
Cell death regulator Aven.
What are the subcellular locations of this protein?
Endomembrane system; Peripheral membrane protein. Note=Associated with intracellular membranes.
Protein: SYEP_MOUSE
Sequence: MAALCLTVNAGNPPLEALLAVEHVKGDVSISVEEGKENLLRVSETVAFTDVNSILRYLARIATTSGLYGTNLMEHTEIDHWLEFSATKLSSCDRLTSAINELNHCLSLRTYLVGNSLTLADLCVWATLKGSAAWQEHLKQNKTLVHVKRWFGFLEAQQAFRSVGTKWDVSGNRATVAPDKKQDVGKFVELPGAEMGKVTVRFPPEASGYLHIGHAKAALLNQHYQVNFKGKLIMRFDDTNPEKEKEDFEKVILEDVAMLHIKPDQFTYTSDHFETIMKYAEKLIQEGKAYVDDTPAEQMKAEREQRTESKHRKNSVEKNLQMWEEMKKGSQFGQSCCLRAKIDMSSNNGCMRDPTLYRCKIQPHPRTGNKYNVYPTYDFACPIVDSIEGVTHALRTTEYHDRDEQFYWIIEALGIRKPYIWEYSRLNLNNTVLSKRKLTWFVNEGLVDGWDDPRFPTVRGVLRRGMTVEGLKQFIAAQGSSRSVVNMEWDKIWAFNKKVIDPVAPRYVALLKKEVVPVNVLDAQEEMKEVARHPKNPDVGLKPVWYSPKVFIEGADAETFSEGEMVTFINWGNINITKIHKNADGKITSLDAKLNLENKDYKKTTKITWLAESTHALSIPAVCVTYEHLITKPVLGKDEDFKQYINKDSKHEELMLGDPCLKDLKKGDIIQLQRRGFFICDQPYEPVSPYSCREAPCILIYIPDGHTKEMPTSGSKEKTKVEISKKETSSAPKERPAPAVSSTCATAEDSSVLYSRVAVQGDVVRELKAKKAPKEDIDAAVKQLLTLKAEYKEKTGQEYKPGNPSAAAVQTVSTKSSSNTVESTSLYNKVAAQGEVVRKLKAEKAPKAKVTEAVECLLSLKAEYKEKTGKDYVPGQPPASQNSHSNPVSNAQPAGAEKPEAKVLFDRVACQGEVVRKLKAEKASKDQVDSAVQELLQLKAQYKSLTGIEYKPVSATGAEDKDKKKKEKENKSEKQNKPQKQNDGQGKDSSKSQGSGLSSGGAGEGQGPKKQTRLGLEAKKEENLAEWYSQVITKSEMIEYYDVSGCYILRPWSYSIWESIKDFFDAEIKKLGVENCYFPIFVSQAALEKEKNHIEDFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPVRLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATFEEAADEVLQILELYARVYEELLAIPVVRGRKTEKEKFAGGDYTTTIEAFISASGRAIQGATSHHLGQNFSKMCEIVFEDPKTPGEKQFAYQCSWGLTTRTIGVMVMVHGDNMGLVLPPRVASVQVVVIPCGITNALSEEDREALMAKCNEYRRRLLGANIRVRVDLRDNYSPGWKFNHWELKGVPVRLEVGPRDMKSCQFVAVRRDTGEKLTIAEKEAEAKLEKVLEDIQLNLFTRASEDLKTHMVVSNTLEDFQKVLDAGKVAQIPFCGEIDCEDWIKKMTARDQDVEPGAPSMGAKSLCIPFNPLCELQPGAMCVCGKNPAKFYTLFGRSY
What is the function of this protein?
Multifunctional protein which is primarily part of the aminoacyl-tRNA synthetase multienzyme complex, also know as multisynthetase complex, that catalyzes the attachment of the cognate amino acid to the corresponding tRNA in a two-step reaction: the amino acid is first activated by ATP to form a covalent intermediate with AMP and is then transferred to the acceptor end of the cognate tRNA (By similarity).  The phosphorylation of EPRS1, induced by interferon-gamma, dissociates the protein from the aminoacyl-tRNA synthetase multienzyme complex and recruits it to the GAIT complex that binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin), suppressing their translation.  Interferon-gamma can therefore redirect, in specific cells, the EPRS1 function from protein synthesis to translation inhibition (PubMed:23071094).  Also functions as an effector of the mTORC1 signaling pathway by promoting, through SLC27A1, the uptake of long-chain fatty acid by adipocytes.  Thereby, it also plays a role in fat metabolism and more indirectly influences lifespan (PubMed:28178239).
What are the official names of this protein?
Bifunctional glutamate/proline--tRNA ligase, Bifunctional aminoacyl-tRNA synthetase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Membrane; Peripheral membrane protein. Note=Translocates from cytosol to membranes upon phosphorylation at Ser-999.
Protein: RM44_YEAST
Sequence: MITKYFSKVIVRFNPFGKEAKVARLVLAAIPPTQRNMGTQIQSEIISDYNKVKPLVKVTYKDKKEMEVDPSNMNFQELANHFDRHSKQLDLKHMLEMH
What is the function of this protein?
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain.  The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
What are the official names of this protein?
54S ribosomal protein L44, mitochondrial, Mitochondrial large ribosomal subunit protein mL53, YmL44.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mL53 family.
What are the subcellular locations of this protein?
Mitochondrion. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1.
Protein: Y631_ARCFU
Sequence: MIKLVEPLKKLIIDGVGVSGEEVEEQLFGGFCECGGVMYQRFWFTRDSEKILVSECEKCWKHKAMIFNSHSFVSHQSVEVLGKYDFVELLKETLGEKEFESLVRKAKNEEFDPVSYTRAKKMLTSMNLDIDEILDQVR
What are the official names of this protein?
Uncharacterized protein AF_0631.