PharMolix/UniProtQA huggingface dataset:
Protein: SYL_PARXL
Sequence: MHEKYVPSDVESAAQGQWRAIDAYKTTEVTDKPKFYCVSMLPYPSGKLHMGHVRNYTINDVMYRYLRMNGYNVLMPMGWDAFGMPAENAAMANNVPPAKWTYDNIAYMKKQMQSMGLAIDWSREVATCSPDYYKWNQWLFLKMLEKGIAYKKTGTVNWDPVDQTVLANEQVIDGRGWRSGALVEKREIPMYYMRITQYADELLNDLEGLGWPERVKIMQQNWIGKSFGVNFGFPYEIDGEQKLLRVFTTRADTIMGVTFCAIAAEHPLATRLAKDKPELQAFIEECKRGGVAEADVATMEKKGMATGFTVTHPLTQEQVEVWIGNYVLMSYGEGAVMGVPAHDERDFAFVKKYGLPVRQVVAVEGKEFSTEAWQEWYGEKTGTLINSGKYDGLNYEQAVDRIAADLKELGLGDKQITWRLRDWGVSRQRYWGTPIPIIHCPTCGDVPVPEKDLPVVLPEDLVPDGTGNPLARSEAFVNCTCPTCGGAAKRETDTMDTFVDSSWYFYRYASPGAKTMVDERTDYWAPMDQYIGGIEHAILHLLYSRFWAKVMRDLGLIRFGEPAKNLLTQGMVLNETYYRENEAGKKTWYNPAEVTVSFDDKGRPVGAILNEDGQPVVLGGVEKMSKSKNNGVDPQLLIDQHGADTARLFVMFAAPPEQSLEWSGSGVEGASRFLRRVWSFSQANEAALRQGGTFDAAQLSDVEKVLRREIYSVLKQADFDYQRLQYNTVVSAAMKMLNALDSAKGARPAVLRETCSVMLRVLYPVVPHLTFQLWQELGYADELGSLLDAPWPKVDEKALEQSEIELVLQVNGKVRGAITVAKDASREAIEQLAAAHEMVAKFSEGKAPKKIVVVPGRLVNVVV
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBL2_STRCI
Sequence: MTEVRSCFSSALRRRQCASTSAAVSATSSPKTCGCRCTSFVTSVPATSSIANGSSASSWAIRAWKTTWSRTSPNSSRSSPRSPASMASTSSYISSTPYLTRSWWVRRALHGHARRIRSMTSTTSSRRAPGRS
What are the official names of this protein?
Uncharacterized 14.2 kDa protein in blaB 3'region.
Protein: IGJ_EQUAS
Sequence: MKNHLFFWGVLAIFVQAVLVTAGDEGERIVLADNKCKCVRVTSRIIPSPENPNEDILERHIRIIIPVNSRENISDPTSPVRTKFVYHLSDLCKKCDPVEVELDNQVVTASQSNICDEDSETCYAYDRNKCYTNRVPLTYGGQTKIVETALTPDSCYPD
What is the function of this protein?
Serves to link two monomer units of either IgM or IgA.  In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces dimers and/or larger polymers.  It also helps to bind these immunoglobulins to secretory component.
What are the official names of this protein?
Immunoglobulin J chain, Joining chain of multimeric IgA and IgM.
What are the subcellular locations of this protein?
Secreted.
Protein: SHOX2_HUMAN
Sequence: MEELTAFVSKSFDQKVKEKKEAITYREVLESGPLRGAKEPTGCTEAGRDDRSSPAVRAAGGGGGGGGGGGGGGGGGGVGGGGAGGGAGGGRSPVRELDMGAAERSREPGSPRLTEVSPELKDRKEDAKGMEDEGQTKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKGVLIGAASQFEACRVAPYVNVGALRMPFQQDSHCNVTPLSFQVQAQLQLDSAVAHAHHHLHPHLAAHAPYMMFPAPPFGLPLATLAADSASAASVVAAAAAAKTTSKNSSIADLRLKAKKHAAALGL
What is the function of this protein?
May be a growth regulator and have a role in specifying neural systems involved in processing somatosensory information, as well as in face and body structure formation.
What are the official names of this protein?
Short stature homeobox protein 2, Homeobox protein Og12X, Paired-related homeobox protein SHOT.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family. Bicoid subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: YRAN_SALEP
Sequence: MAQIPARGDCSRQLTRKQAGDAWEAAARRWLESKGLRFIAANVRERGGEIDLIMRDGKTTVFVEVRYRRSGLYGGAAASVTRSKQHKLLHTARLWLARQNGSFDTVDCRFDVLAFTGNEIEWFRDAFNDHS
What are the official names of this protein?
UPF0102 protein YraN.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: YBOX3_HUMAN
Sequence: MSEAGEATTTTTTTLPQAPTEAAAAAPQDPAPKSPVGSGAPQAAAPAPAAHVAGNPGGDAAPAATGTAAAASLATAAGSEDAEKKVLATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSRYAADRRRYRRGYYGRRRGPPRNYAGEEEEEGSGSSEGFDPPATDRQFSGARNQLRRPQYRPQYRQRRFPPYHVGQTFDRRSRVLPHPNRIQAGEIGEMKDGVPEGAQLQGPVHRNPTYRPRYRSRGPPRPRPAPAVGEAEDKENQQATSGPNQPSVRRGYRRPYNYRRRPRPPNAPSQDGKEAKAGEAPTENPAPPTQQSSAE
What is the function of this protein?
Binds to the GM-CSF promoter.  Seems to act as a repressor.  Binds also to full-length mRNA and to short RNA sequences containing the consensus site 5'-UCCAUCA-3'.  May have a role in translation repression (By similarity).
What are the official names of this protein?
Y-box-binding protein 3, Cold shock domain-containing protein A, DNA-binding protein A, Single-strand DNA-binding protein NF-GMB.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SIVA_HUMAN
Sequence: MPKRSCPFADVAPLQLKVRVSQRELSRGVCAERYSQEVFEKTKRLLFLGAQAYLDHVWDEGCAVVHLPESPKPGPTGAPRAARGQMLIGPDGRLIRSLGQASEADPSGVASIACSSCVRAVDGKAVCGQCERALCGQCVRTCWGCGSVACTLCGLVDCSDMYEKVLCTSCAMFET
What is the function of this protein?
Induces CD27-mediated apoptosis.  Inhibits BCL2L1 isoform Bcl-x(L) anti-apoptotic activity.  Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis.
What are the official names of this protein?
Apoptosis regulatory protein Siva, CD27-binding protein, CD27BP.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=In the nucleus, accumulates in dot- like structures.
Protein: SUCA2_ARATH
Sequence: MSRQVTRLLGSLRHSGGGCSGSSKVCSLTSLVQSRSFGTTPPPPAAVFVDKNTRVICQGITGKNGTFHTEQAIEYGTKMVAGVTPKKGGTEHLGLPVFNTVAEAKAETKANASVIYVPAPFAAAAIMEGLAAELDLIVCITEGIPQHDMVRVKAALNSQSKTRLIGPNCPGIIKPGECKIGIMPGYIHKPGKIGIVSRSGTLTYEAVFQTTAVGLGQSTCVGIGGDPFNGTNFVDCLEKFFVDPQTEGIVLIGEIGGTAEEDAAALIKENGTDKPVVAFIAGLTAPPGRRMGHAGAIVSGGKGTAQDKIKSLRDAGVKVVESPAKIGAAMFELFQERGLLK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA.  The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit alpha-2, mitochondrial, Succinyl-CoA synthetase subunit alpha-2, SCS-alpha-2.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase alpha subunit family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: Y3697_METBF
Sequence: MSDPINEHANEPASFPIKEHFQLKETIVTIAADNLAHIEAAKEAIRIHRAALETYIFSDPYFQLTLEPYECPENAPEVVRRMVKAGNTMGIGPMSAVAGTISALAVESMVKAGAKYAIVDNGGDIALINDRPVVVGIYAGQSTIKNLGLVFEPRGSITGVCTSAGTVGPSISFGMADAAAVFSDDVSLADAAATALGNEVNIGKESVEASFKAVKGIPEIKGALVIQGEYIGMWGQVPRVTRADVRYEYITKA
What are the official names of this protein?
UPF0280 protein Mbar_A3697.
What is the protein family that this protein belongs to?
Belongs to the UPF0280 family.
Protein: LKTC_PASSP
Sequence: MNQHYFNLLGNITWLWMNSPLHREWSCELLARNVIPAIENQQYMLLIDNDVPIAYCSWADLSLETEVKYIKDISSLTPEEWQSGDRRWIIDWVAPFGHSQLLIKNVSEIPDYSRQIYTLLSKTKRTGKIAYFKGGNLDKKTAKKRFDTYQERLGAALKNEFNFTK
What is the function of this protein?
Involved in fatty acylation of the protoxin (LktA) at two internal lysine residues, thereby converting it to the active toxin.
What are the official names of this protein?
Leukotoxin-activating lysine-acyltransferase LktC, Leukotoxin C, Toxin-activating protein C.
What is the protein family that this protein belongs to?
Belongs to the RTX toxin acyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPB4_DROME
Sequence: MSFMNPVDMVDEDAADLQFPKEFENAETLLISEVHMLLDHRKRQNESADEEQEFSEVFMKTYAYTDSFRKFKNKETIMSARSLLMQKKLHKFELAALGNLCPEAPEEAKALIPSLEGRFEDEELRQILDDIGTKRSLQY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Associates with POLR2G.
What are the official names of this protein?
DNA-directed RNA polymerase II subunit Rpb4.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RR8_PINTH
Sequence: MGNDTITNLITSIRNADMVEKGTVRVTATNITKNIGRILLREGFIEDVREHQEGQKYFLISTSKYRRRKKRTYMTTSKRTSKPGLRIYSNYREIPKVLGGMGIVILSTSQGILTDREARQKKIGGEILCYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL4_STRP3
Sequence: MANVKLFDQTGKEVSSVELNDAIFGIEPNESVVFDVVISQRASLRQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLPQKVRRLALKSVYSAKVAEDKFVAVEGLSFAAPKTAEFAKVLSALSIDTKVLVLVEEGNEFAALSARNLPNVTVATAATASVLDIVNADKLLVTKEAISTIEEVLS
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: EX7L_ECODH
Sequence: MLPSQSPAIFTVSRLNQTVRLLLEHEMGQVWISGEISNFTQPASGHWYFTLKDDTAQVRCAMFRNSNRRVTFRPQHGQQVLVRANITLYEPRGDYQIIVESMQPAGEGLLQQKYEQLKAKLQAEGLFDQQYKKPLPSPAHCVGVITSKTGAALHDILHVLKRRDPSLPVIIYPAAVQGDDAPGQIVRAIELANQRNECDVLIVGRGGGSLEDLWSFNDERVARAIFTSRIPVVSAVGHETDVTIADFVADLRAPTPSAAAEVVSRNQQELLRQVQSTRQRLEMAMDYYLANRTRRFTQIHHRLQQQHPQLRLARQQTMLERLQKRMSFALENQLKRTGQQQQRLTQRLNQQNPQPKIHRAQTRIQQLEYRLAETLRAQLSATRERFGNAVTHLEAVSPLSTLARGYSVTTATDGNVLKKVKQVKAGEMLTTRLEDGWIESEVKNIQPVKKSRKKVH
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSM6_MYCTU
Sequence: MILFSPIGTADPITALGDGPMLHIVRHYRPIVVVLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSAEFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLELMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRLPDQVSNLIRGAMHRSRLEHLVAPKFFKDTAFTYDPANKVAEYISALALLAKREQWAEFARSATPAITIVLRAAVAKHLPEDRYLDDMGRVDRRKLEREPEIRCALKHPPKSPNAEWYLYTKDWLALLRQFAPDRVGALEVLGRFESRVRNTAAHEIVSISEDRITKDGGLLPEQLLKILARETGADLTLYDRLNDEIIRQIDMAPLG
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  The type III-A Csm effector complex binds crRNA and acts as a crRNA-guided RNase, DNase and cyclic oligoadenylate synthase; binding of target RNA cognate to the crRNA is required for all activities (Probable).  This CRISPR-Cas system protects bacteria against transformation with plasmids containing DNA homologous to its spacer regions (PubMed:29979631).  This subunit is a single-strand-specific endoribonuclease (ssRNase) that is stimulated by cyclic oligoadenylates (cOA) produced by the Cas10 subunit of the Csm effector complex (By similarity).
What are the official names of this protein?
CRISPR system endoribonuclease Csm6, CRISPR type III-A associated protein Csm6.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated Csm6 family.
Protein: TM104_DROME
Sequence: MPRLVNGREAAPTYSNLVGFIFIFNLIVGTGALTLPGVFARAGWMLSLIVIVLLAIISYMTVTFIIEAMACANAIRNWQTLQALRQSRSSAENSENDDNADDVSLASGAEQVGDFERVPLTIQNREFHYYQLSHKFELGEMATLFFNEFGRVMFYLCLIVYLYGDLSIYSAAVARSLRDVVCDQTNGTDTNNLMYWPGDFENNTSLACWKEHTISRLNMYRVLLIGFTLIFGPFVYFNVQKTKYLQMLTAAFRWMAFTLMICISLKLLISRGAKGHPATFNVYGIPSLFGACVYSFMCHHSLPSLLAPIRHKSMVSKILSIDYIIICAFYILLAMTGIFAFERIEDLYTLDFLPYDVAYVDFWSGLLICIDYFLALFPIFTLSTSFPIVAITLKNNLQSLFLDMSQYESYSVILRLCFPLLAIIPPFCITYFTESLSSLVAFTGTYAGTGIQYIIPVFLVYFARRTCSELLGSGVVNRFKSPFKSSAWLVFVFIWSILCVCLVSINLFS
What are the official names of this protein?
Transmembrane protein 104 homolog.
What is the protein family that this protein belongs to?
Belongs to the TMEM104 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: COBT_SHEB5
Sequence: MSQSAVSFQISPVSKTQDPLIQQKIDLKTKPPGALGQLESLALQIARVQATDSQQTDQPQNTVLKIVQPTMLVFAGDHGIAAEGVSIAPSEVTRQMVQNFAHGGAAINVFCRQVGFTLEVIDCGILTPVEGVEGIIDQRLGAGTGAIHLEPAMALETVDKGFAMARDLIERHHQAGCNLVAFGEMGIGNTSAAAAIMAAIMQLDVIDCVGRGTGINSETLERKLMLIELALLLHQSALTGPKSVLACLGGFEIVQMTGAMLAAAERKMLVVVDGFIATAAALVAVQIAPNVRDYLIFAHQSDEQGHKRMLEFLQAKPLLSLGLRLGEGTGAALALPLIQASVNFYNQMASFSDAGIEAVV
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: NHAP2_VIBCM
Sequence: MDAVTINSFFMIGALLIGISVLLSPVSSKLGIPILLVFLAVGMLAGEDGIGQIAFDNYPVAYLVSNLALAIILLDGGMRTRVASFRVAFWPSVSLATLGVAVTTLLTGLLAMWLFNLSLLQGVLVGAIVGSTDAAAVFSLLKGRSLNERVGATLEIESGTNDPMAVFLTVTLIAVLGSAETNLSAGFLLLSFIQQFGVGALLGLAGGWILWWLINRNQLPEGLYSILAVSGGLMIFALSNALGGSGILSIYLTGLLLGNRPTRSRHAILNVLDGMTWLAQIGMFLVLGLLVTPSELMEIALPGLALAVGMILFARPIAVWIGLAPFKSFTAREKWFVSWVGLRGAVPIILAVFPMMAGLPNAQLYFNLAFFVVMVSLVVQGGTLTKAMSLAKVELPPKPEPISRTGVEIYPTSEWELFIYKLKADKWCIGEPLRNLFMPEGTRIAAVFRDNQLLHPSGSTELCEGDTLCVMAQERDLESLSRLFSEAPEKASLARFFGDFFLDIEAKLQDVALLYGLDLGELEADAKLKDLVLEHLGETPVLGDYFEWHGLQWVVADVVDWKVTKIGLRLPPEEELQEGAE
What is the function of this protein?
K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.
What are the official names of this protein?
K(+)/H(+) antiporter NhaP2, Potassium/proton antiporter NhaP2.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FMT_CHLCH
Sequence: MRIIVMGTPDFAVPSLQAIAAMGNGFDIVLVVTGQDKPRKSKHAAAEASPIKQAALALNLPVHEVDDVNDPHFAEIVAAYKPDVIVVAAFRILPPAVYSQARLGAFNLHASLLPAYRGAAPVNWAIMNGEEETGVTTFFLQQRVDTGTIIMQQKTAIAPEENATELIVRLANIGADVVVETLRRIAAKNAATAPQDDSLASRAPKLTRINTRINWEQPVATLHNFIRGLALKPSAWTTFNDKTLKIFRTTLSTPEHDHPSAPAGSLLVSHGKLYVHGSDGWLELLALQLEGRKPMEAADFARGLHVEGEALRLV
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: FUMC_LISIN
Sequence: MERIERDTLGEISVDATKYWGAQTERSRRNFAIGDNYMPKEIIYAFAQLKKAAAKVNALEGKLSEAKSVAIGNVCDQIIQGELDEHFPLVVWQTGSGTQSNMNVNEVIAHVANLTLGEEKVHPNDDVNMSQSSNDTFPTAMHIAAYQALVTKLLSEITKMEEVLTTKKNQYMQLVKIGRTHLQDATPLTLGQEISGWEACLTNNKNYLESSMKAILPLAIGGTAVGTGLNASKDFGDKVAEELRKQTGYPFTSDSNKYFALTSHSPINFVHGAIRSLASDLMKIANDIRLLASGPRSGIGELTLPANEPGSSIMPGKVNPTQCEAITMVAAQVMGNDTTINIAASQGNFELNVYKPVIIFNFLESITLLSDSMRSFRIHCLEGLTANESVIEAKVNDSLMLVTALNPHIGYEKAAKIAKLAFDENTTLKEAAIKTGFVTEKEFDLWIDPLKMTNL
What is the function of this protein?
Involved in the TCA cycle.  Catalyzes the stereospecific interconversion of fumarate to L-malate.
What are the official names of this protein?
Fumarate hydratase class II, Fumarase C, Aerobic fumarase, Iron-independent fumarase.
What is the protein family that this protein belongs to?
Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_CAUVN
Sequence: MARIAGVNIPTNKRVLIALQYIHGIGQKSAREIITKVGIEDARRVNQLTDAEVLQIRETIDRDYTVEGDLRRENSMNIKRLMDLACYRGLRHRKGLPVRGQRTHTNARTRKGPAKPIAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: NDUB8_PONPY
Sequence: MAVARTGVLGVQWLQRASWNMMPLGARTASHMTKDMFPGPYPRTPEERAAAAKKYNMRVEDYEPYPDDGMGYGDYPKLPDRSQHERDPWYSWDQPDLRLNWGEPMHWHLDMFNRNRVDTSPIPVSWNVMCMQLFGFLAFMIFMCWVGEVYPVYQPVGPKQYPYNNLYLERGGDPSKEPERVVHYEI
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial, Complex I-ASHI, CI-ASHI, NADH-ubiquinone oxidoreductase ASHI subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFB8 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
Protein: FER_BUCAI
Sequence: MPKVLFLPHKILLPKSIECEAQTGETILTVALRNNIKLEHACEQSCACSTCHCIIKKGFFSLSGWSEKEDDILDKAWGLQSESRLSCQAVIGKSDIEVEIPLYNLNYTVEY
What is the function of this protein?
Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
2Fe-2S ferredoxin.
What is the protein family that this protein belongs to?
Belongs to the adrenodoxin/putidaredoxin family.
Protein: PREP_GIBZE
Sequence: MLRNAAAGARKAVTELSQFPKPGEKLHGFTLVRSKHVPELELTALHLQHDKTGADYLHIARDDSNNVFSIGFKTNPPDDTGIPHILEHTTLCGSEKYPIRDPFFKMLPRTLSNFMNAFTASDHTFYPFATTNAQDFKNLMSVYLDSTLHPLLKKSDFTQEGWRIGPENPLAEDEASKKLVFKGVVYNEMKGQMSDAGYLYYIRFHDHIFPDINNSGGDPQKITDLTYEQLQKFHAEHYHPSNAKVFTYGDMPLIDHLKQVDTQLQAFEKIQGDKQVHEPVTLNGPKEVTLYGPLDPLVDQDRQYKTSVSWIMGDTTDVLESFSLALLSTLLMDGYGSPLYRGLIEAGMGADWSPNAGYDSSAKKGIFSIGLTGVQEGDVPKLKEKVQQILRDARNKGFDKTKIDGSLHQLELSLKHKTANFGFSMLNRLKPKWFNGVDPFDSLAWNDTINGFQAKMAEGNYLEGLIDKYLLNDNTLTFTMAPSTTYGEDLVKEEQERLSTRIQAAIKEAGSEEKARKHFEKQEQELLVEQNKTNTEDLGCLPTVHVKDIPRSKEAVVVRDENANGTKIQWHEAPTNGLTYFRAINTLENLPDELRELVPLFTDSIMRLGTKDLNMEQLEDLIKLKTGGVSVGYHCTPSPTDFHAASEGIIFTGMALDHNVPVMFDIIQKLVLGTDFDSPEAALRIRQLLQASADGVVNDIASTGHRFAMGSAESGLTRSAWLRQQVSGLSQVQLVTSLASRPETDKLEDVISKLKQIQNLALVGGNLRTAITCGSESVAANGASLQNFVGNLSRDPLNLKNPSPRQLPKDSKTFYPLPYQVYYGGLSLPTTSYTSAEGAPLQILSQLLTHKHLHHEIREKGGAYGGGAYSRALDGLFGFYSYRDPNPQNTLSIMRNAGQWAVDKKWSDRDLEEAKISVFQGVDAPKSVNQEGMGRFLSGITEEMKQKKREQFLDVTKDQVREAAQRYLVDGLAKGEGRVAFLGEKQAWVDGEWQIREMDVKGAE
What is the function of this protein?
Degrades mitochondrial transit peptides after their cleavage in the intermembrane space or in the matrix, and presequence peptides; clearance of these peptides is required to keep the presequence processing machinery running (By similarity).  Preferentially cleaves the N-terminal side of paired basic amino acid residues (By similarity).  Also degrades other unstructured peptides (By similarity).  May function as an ATP-dependent peptidase as opposed to a metalloendopeptidase (By similarity).
What are the official names of this protein?
Presequence protease, mitochondrial, PreP, Pitrilysin metalloproteinase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M16 family. PreP subfamily.
Protein: HN_PI3HW
Sequence: MEYWKHTNHGKDAGNELETSMATHGNKLTNKIIYILWTIILVLLSIVFIIVLINSIKSEKAHESLLQDINNEFMEITEKIQMASDNTNDLIQSGVNTRLLTIQSHVQNYIPISLTQQMSDLRKFISEITIRNDNQEVLPQRITHDVGIKPLNPDDFWRCTSGLPSLMKTPKIRLMPGPGLLAMPTTVDGCVRTPSLVINDLIYAYTSNLITRGCQDIGKSYQVLQIGTITVNSDLVPDLNPRISHTFNINDNRKSCSLALLNTDVYQLCSTPKVDERSDYASSGIEDIVLDIVNYDGSISTTRFKNNNISFDQPYAALYPSVGPGIYYKGKIIFLGYGGLEHPINENVICNTTGCPGKTQRDCNQASHSPWFSDRRMVNSIIVVDKGLNSIPKLKVWTISMRQNYWGSEGRLLLLGNKIYIYTRSTSWHSKLQLGIIDITDYSDIRIKWTWHNVLSRPGNNECPWGHSCPDGCITGVYTDAYPLNPTGSIVSSVILDSQKSRVNPVITYSTATERVNELAIRNRTLSAGYTTTSCITHYNKGYCFHIVEINQKSLNTFQPMLFKTEIPKSCS
What is the function of this protein?
Neuraminidase activity ensures the efficient spread of the virus by dissociating the mature virions from the neuraminic acid containing glycoproteins.
What are the official names of this protein?
Hemagglutinin-neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses hemagglutinin-neuraminidase family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type II membrane protein. Host cell membrane; Single-pass type II membrane protein.
Protein: HISX_BUCMH
Sequence: MKNCLKIIHWDRCSIEEREKILSRPILDDLSAIKKQVKTIISDVNSLGDQALYNYTNIFDKIKLNNIKISHQDLVKAELCIDVKAKNAIQVAIDNIRTFHISQNISTLNIEINKGIYCQQIVRPIGSVGLYIPGGSAPLLSTVLMLAIPARIAGCKKIVLCSPPPITNEVLYASKICGVQEIFQVGGAQAIAALGFGTETI
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: RS13_MYCSP
Sequence: MARVLNIEIPNNKKARISLTYIFGIGPTIAKQILADANVDGEKRVKELTEEELTRIRDEAKKYTTEGDLKREINLNIKRLMEIKSYRVIRHRKDTCKRSTKKNARTRKGPKKDNRWKER
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: RNH2B_BOVIN
Sequence: MARGADGGDGASVWQHVFLLPEYLKDDSKKMKSGLVFVKLANPCSGEGTIYLFNMCLPQLFEIKVFKEKNHSWFINESVQSGGLLHFATPVDPLFLLLHYLIKADKESFQGKFQPLDQVVMDDMFPDCILLLKLPELEKLLQHVTEEKEVDKKKYYKYSKEKTLKWLGKKVNQTMAALKTNKVNVSARVQSTAFFSGGQVSSDKDEDYVRYAHGLISDYIPKQLSDDLSKYLKLPEPPASVRNPPSKKAKLSDEPVMAKEDYTKFNSKDFKTVKKNSKMTAAQKALAKVDKSGMKSIDSFFGTKHVKKK
What is the function of this protein?
Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids.  Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication.  Mediates the excision of single ribonucleotides from DNA:RNA duplexes (By similarity).
What are the official names of this protein?
Ribonuclease H2 subunit B, RNase H2 subunit B, Ribonuclease HI subunit B.
What is the protein family that this protein belongs to?
Belongs to the RNase H2 subunit B family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS25_HUMAN
Sequence: MPPKDDKKKKDAGKSAKKDKDPVNKSGGKAKKKKWSKGKVRDKLNNLVLFDKATYDKLCKEVPNYKLITPAVVSERLKIRGSLARAALQELLSKGLIKLVSKHRAQVIYTRNTKGGDAPAAGEDA
What is the function of this protein?
Component of the small ribosomal subunit (PubMed:23636399).  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399).
What are the official names of this protein?
40S ribosomal protein S25, Small ribosomal subunit protein eS25.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS25 family.