PharMolix/UniProtQA huggingface dataset:
Protein: DMRT2_MOUSE
Sequence: MTEGQAVPGVGDWEIDVESLDLEEDSCGTPLRATPPQEPSPAAADGEEDEDEEEEDEDVEDEGDGEEPGVSSEVPGRPEQPGGLAPRPPPAAQALPAAAAAPERGATAGGGAEPRKLSRTPKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGLSGKQNNFDRKAVYQRQVRAPSLLAKSILEGYRPMTAETYLGGTLPLPPPVSDRMRKRRAFADKELENIMLEREYKEREMLETSQAAALFLPNRMVPGPEYSSYKGTYSPTAGELPSKDFCNFLPTCLDLTMQYSGSGNMELISSNVSVATTYRQYPLSSRFLVWPKCGPISDTLLYQQYLLNATTSVQALKPGTGWDLKGTRVQDGLSAEQDMMPPKLEGSLVLPHLPEVPASRTDLQVHQVVPERSAFSPPGRNFSPIVDMDCLAAQGHVLTKLSKENTRPSLPLKTNPFHSVFQQTLSDKSGPELNAPFVKEAFEETPKKHRECLVKESQKYTFTIDRCAKDLFVAKQVGTKLSANEPLSFSVESILKRPSSAVTHVSQ
What is the function of this protein?
Transcriptional activator that directly regulates early activation of the myogenic determination gene MYF5 by binding in a sequence-specific manner to the early epaxial enhancer element of it.  Involved in somitogenesis during embryogenesis and somite development and differentiation into sclerotome and dermomyotome.  Required for the initiation and/or maintenance of proper organization of the sclerotome, dermomyotome and myotome.  Is not required for sex determination and/or differentiation in embryonic development.  Also not involved in symmetric somite formation and hence does not regulate the laterality pathway that controls left-right asymmetric organ positioning.
What are the official names of this protein?
Doublesex- and mab-3-related transcription factor 2, Doublesex-like 2 protein, Terra.
What is the protein family that this protein belongs to?
Belongs to the DMRT family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS18_XANC5
Sequence: MSKFFRRRKFCKFTAEGVKEIDYKDLNTLRQYLTENGKIVPSRVTGTKSKYQRQLATAVKRARFLALIPYTDNHDV
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: BEV1K_BETPN
Sequence: MGVFNYESETTSVIPAARLFKAFILEGDTLIPKVAPQAISSVENIEGNGGPGTIKKITFPEGSPFKYVKERVDEVDHANFKYSYSMIEGGALGDTLEKICNEIKIVATPDGGSILKISNKYHTKGDHEMKAEHMKAIKEKGEALLRAVESYLLAHSDAYN
What is the function of this protein?
May be a general steroid carrier protein.
What are the official names of this protein?
Major pollen allergen Bet v 1-K, Allergen Bet v I-K.
What is the protein family that this protein belongs to?
Belongs to the BetVI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_STRA1
Sequence: MAKPTRKRRVKKNIESGVAHIHATFNNTIVMITDVHGNALAWSSAGALGFKGSRKSTPFAAQMAAEAAAKSAQEHGLKTVEVTVKGPGSGRESAIRALAAAGLEVTAIRDVTPVPHNGARPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: TIG_ANAMM
Sequence: MQRFYVVKEVLSDKLKRVYEFTVGNEYLEQQVDDRLREIAANVRMDGFRKGKVSLDLVRRNCGEDVVREVLSKVVDDASSQFMQEGGFGDVVTSEVRITSHPKVCSTEGKGGDLVYELQFELMPEVPSINPEEIALKEMEAEIGQEDVDKFIGELKTRYPNFVASDSPKQRAAAGDKVVIDYNSSFKGKALRGGSAKGFVAVLGGGHLPKEFEDKITGMKVGDVKEFKLGFPSDYRVRLFAGKEVEMSVKLVSIMVPKDVGDHEELAKSCGFGCAEDMVNFATESLKGRFAFMSDALMRKELFDHMETIYQGQVPESVVSQESARIRRELAPSELEAMGEDGILKEAERRVRLGMLLMKVSQDNNIAVEARDISAFVQSNYLNYGASLESVLKLLRSNQGVRDHIRGKVLEDKVVRYMVAKAKKERQNVPAGDLKSLFESI
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: DXR_LISMF
Sequence: MKKIILLGATGSIGTQTLAIIRENPEKFQIVALSFGRNMERGRAIIKEFKPKMVAVWHTRDRVILEAEFPNVKFFNGLEGLREVATYLDGDVLLNAVMGSVGLLPTLDAIEAGKAIAIANKETLVTAGHLVMRAAKEKNISLLPVDSEHSAILQALNGENTERIEKLVLTASGGSFRDKTREQLSEVTVKEALKHPNWNMGNKLTIDSATMFNKGLEVMEAHWLFGVDYDDIEVVIQRESIIHSMVQFVDGSFIAQLGTPDMRMPIQYALTYPDRLYIPYEKEFRITDFSALHFEKVDYERFPALKLAYNAGKIGGTMPTVLNAANEIAVAGFLNGQVAFYNIEALVENAMNRHTSISDPDLDTILQVDQETRAYVKTLL
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: RLA2_PLAF7
Sequence: MAMKYVAAYLMCVLGGNENPSTKEVKNVLGAVNADVEDEVLNNFIDSLKGKSCHELITDGLKKLQNIGGGVAAAPAGAAAVETAEAKKEDKKEEKKEEEEEEEDDLGFSLFG
What is the function of this protein?
Plays an important role in the elongation step of protein synthesis.
What are the official names of this protein?
60S acidic ribosomal protein P2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein P1/P2 family.
Protein: WASC3_DANRE
Sequence: MDADGLPIVGSGVDLTKVPAIQQRRIVAFLNQFIVHTVRFLNRFSTVCEEKLSTVSLRIQQIETTLSILEAKLASIPGLEEVTVDGVRAPAETNGPAADTSRATAPPAEASQQTQAAPQEPKTEAPAENIMTVAKDPRYARYLKMVQVGVPVMAIKNKMMMEGLDPNLLDTPDAAVPDASKKRLEEQDDDSSGSESSFSD
What are the official names of this protein?
WASH complex subunit 3, Coiled-coil domain-containing protein 53.
What is the protein family that this protein belongs to?
Belongs to the CCDC53 family.
Protein: MRR1_CANAL
Sequence: MSIATTPIETPKSPKSTEPQVRKRKKVSTVCTNCRKRKIRCDRQHPCNNCIKSKKHNACVYDDGQVSPANFSTNGSSHGNTVPESRPYEESARIPIRFDAEAPRKKSKPNTPNNERKNSKKSPDNTVANNQQTASENEVTITLSELNMLKQRLQNIEANINAQSNPQSNPSYVPQTPAYPTQPNILPPPVSFNSWSPKQSNERVMFSPQQRLTTNYNVSHTRGQSPSIQLPPLSFKDTPRASIDSAPLYSEMSPPRSDLIASSLTSPESIQMSVSGDVVGVNPYLNETETINFYDGYTSICVRDFRRVNHGPFAWSSLMRKDKALSSLWNHILKKKEKKNVASQTFVFGQDVHEISQENTQLVASESNESETKFKKKTLETFGFNDVVPYDILKKKLQTQINKTTSPLGLTLYEEQVNMELQLVDRIHQQLPKKKVLWKLIDRFFSLLYPFMPFLDEIDFRESVTKIIGETEYKDEKIKELKVEKRLDLAVIGVLLIILRMSYLSLFCNKESVNEMRLKTTDPSPEAQDMKYLLQNPIGISLIDSAQNCLQYFDIFRKTSMPVLQCAYFLQLYHIFAPEDGDDGDGADTYALNSMVVRMAYSMGLNREPDNFKDVLNDKRQNHLGRKIWHFLVIGDVHNSYAFGTPKLIGDDFYDTKVPFIEEGNENLIDKSLDQYVTKSVFPGYFSIYNSVDQILKLILSVSRRSKVSEICKILNQFEIGIAEQYGTLSDCLKPKENLIHIFARNMPVKMYISLKSFLVSVYFHLFLYYEHKNDSLSFFYLRKILKTGAGDIMPHYFELLGNSEVVCDMVINPKLIQIIHKANQINIALIIRVNMSIYRMKNSQHHAENCKKDDFYYSYYKELCKFSSCLTRCAEVGIAAVSKLSTRYYYAWKITKGHNFLLKTITSMEFYEKESTNAQEITLPKYKLEQIADLENICEVALNKLGKTSVMGDEFCSNVNYKKYKGDQTYSTSSESSSTPNKDSPLDSRKYTNDFGLDLVNNQEIDKIWLQMLSLKSEEAQQQRQQESQPFTSSQSQSQSPLTSANQGYMPRPESRRGSYYGNTPFALENLNFDGFGGQSKSSNNGEADLSSFDFFVDLPFDQLFTN
What is the function of this protein?
Transcription factor that acts as the central regulator of the MDR1 efflux pump.  Other target genes include those encoding oxidoreductases, whose up-regulation in fluconazole-resistant isolates may help to prevent cell damage resulting from the generation of toxic molecules in the presence of fluconazole and thereby contribute to drug resistance.
What are the official names of this protein?
Multidrug resistance regulator 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: CLS_ORYSJ
Sequence: MPPSVATHASLLLKAAAAAAHLHPKPFFSPRAAPPRIPSAPAPPAAGGSRYRPTTTTTAAATATSATAACRWFRWPPPAQAPVRGLCSLPHSGGGGGGGEGMGSEGVGRRRRVVAPAVNGVAKDGAPQPPPPKLLTLPTVLTIGRVAAVPLLISTFYMEGPWAATATTGIFLAAAVTDWLDGYIARKMQLGTPFGAFLDPVADKLMVAATLVLLCTKPLEISLLRDGPWLLTVPAIAIIGREITMSAVREWAASQNTKVLEAVAVNNLGKWKTATQMTALTILLASRDKSLPAQDALVTSGIALLYVSAGLAIWSLVVYMRKIWRILLK
What is the function of this protein?
Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG).  CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions.
What are the official names of this protein?
Cardiolipin synthase (CMP-forming), mitochondrial, CLS.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GSA_GEMAT
Sequence: MTEMVPHARSAEIMARARMRFPGGVNSPVRAFRGVGGEPFVAARGKGARIWDVDGNEYFDYVLSWGPLVLGHAPDVVLHAVSQAMLEGTSFGMPTAREVELADAIAGRMPHLEMVRFTSSGTEATMSIARLARAVTKREHILKFDGCYHGHGDSFLVRAGSGVATLGLPDSPGVPEALAKLTLTCAFNDLDAVERIARDVPLAAIMLEPIVGNSGFIEPTPGFIQGLRRIADETGALLVFDEVMTGFRIAFGGATEYFGVTPDLTALGKVIGGGLPVAAYGGSRTLMEHIAPTGPVYQAGTLSGNPLAMAAGIATLGALTRSVHDEITNQTAALVDGLRGIATRRGVPLSARHVGSMWGFFFRDGDVHSFDDAKQSDVALFRRFFHAARTRGVSLAPSAFEAAFMSAAHGPAEVGETLSRLDDALGAALTDTAGH
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LGL1_ENTH1
Sequence: MIILVLLISYSFGKTQDGKDQLSPNYPYGKMNKDVNFNKPFTSAVDSYQIQQYAENGVFSANQENYVRAKCKTCCRVIFASDYNYKTNTQFTDEDDKKGDERYVMDMEFDDKRSVRFRNGGYEQNILLRPLKQGNELQFFEFAPYRMYTSYAIPKRVHDIRGGANEGATLIIWPKNPPLSDAPGTRNQRFVYVHPYPTEWYPEYNSTTKYTQNGKTVIKTLKWPTYKRHFYLPYRLDVDLCYQARKATDGRSTWTGNKNLNTTSKSYQIIASRCSATEARQIFIPVFA
What is the function of this protein?
Light subunit of a heterodimeric lectin; the heavy subunit binds galactose and N-acetyl-D-galactosamine of host glycoproteins and thus mediates adhesion to host cells.
What are the official names of this protein?
Galactose/N-acetyl-D-galactosamine lectin light subunit 1, Gal/GalNAc lectin light subunit 1, Galactose-inhibitable lectin 35 kDa subunit.
Protein: CEAS1_HUMAN
Sequence: MFCLLHLCFYLANFASSIKRTHAVNGCCGLQMIALWAQSSGNADARVEEILAGEERRLAALLGSQGMRFWVCLAACRAMWGLAARRGRAEDSSSSPVDASKFPWRGGQHRTTMMPCLLRVGVFRPCHVRPTGDPSCDVQPPRLGFSRVPDTQVAFYGSGHWDPTPFSVHSCFFNFQVRKIIFLL
What are the official names of this protein?
Putative uncharacterized protein CELF2-AS1, CELF2 antisense RNA 1, CELF2 antisense gene protein 1.
What are the subcellular locations of this protein?
Secreted.
Protein: DXR_CHLTB
Sequence: MKHLALIGSTGSIGRQVLQVVRSIPDTFIIETLAAYGRNQEALISQIREFNPRVVAVREETTYKELRKLFPHIEILLGEEGLVSVATEPSVTITIVASSGIDALPAVIAAIRQKKTIALANKESLVAAGELVTTLARENGVQILPIDSEHNALFQCLEGRDSSTIKKLLLTASGGPLRNKSKEELQKVSLQEVLRHPVWNMGPKITVDSSTLVNKGLEIIEAFWLFGLEAVEIEAVIHPQSLVHGMVEFCDGTILSVMKPPSMLFPIQHVLTFPERSPAIGPGFDFLSNRTLEFFPIDEDRFPSVHLAKRVLLEKGSMGCFFNGANEALVHRFLAGEISWHQIVPKLQALVDQHRVQSCLSLEEILSVDAEARARAQEC
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: GATC_STRR6
Sequence: MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEVDTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEQDNYYIKVPAILDDGGDA
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit C, Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: GABR_BACSU
Sequence: MDITITLDRSEQADYIYQQIYQKLKKEILSRNLLPHSKVPSKRELAENLKVSVNSVNSAYQQLLAEGYLYAIERKGFFVEELDMFSAEEHPPFALPDDLKEIHIDQSDWISFSHMSSDTDHFPIKSWFRCEQKAASRSYRTLGDMSHPQGIYEVRAAITRLISLTRGVKCRPEQMIIGAGTQVLMQLLTELLPKEAVYAMEEPGYRRMYQLLKNAGKQVKTIMLDEKGMSIAEITRQQPDVLVTTPSHQFPSGTIMPVSRRIQLLNWAAEEPRRYIIEDDYDSEFTYDVDSIPALQSLDRFQNVIYMGTFSKSLLPGLRISYMVLPPELLRAYKQRGYDLQTCSSLTQLTLQEFIESGEYQKHIKKMKQHYKEKRERLITALEAEFSGEVTVKGANAGLHFVTEFDTRRTEQDILSHAAGLQLEIFGMSRFNLKENKRQTGRPALIIGFARLKEEDIQEGVQRLFKAVYGHKKIPVTGD
What is the function of this protein?
Activates the transcription of the gabTD operon.  Is also a repressor of its own expression, both in the presence and absence of GABA.  Binds specifically to the DNA region overlapping the -35 region of the gabT promoter and the -10 and +1 regions of the gabR promoter.  Principally regulates the utilization of gamma-aminobutyrate.
What are the official names of this protein?
HTH-type transcriptional regulatory protein GabR.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
Protein: RL22_CAMJ8
Sequence: MSKALIKFIRLSPTKARLIAREVQGMNAELAMASLKFMPNKGAKYIANAISSAVANGGFEANEVIVKSCRVDAAAVLKRFRPRARGSASRIRKPTSHILVEVAKAEVKAEEKKTVAKKAPAAKKTTTTKAPAKKTTSTKKATAKKES
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: GHRB_SALDC
Sequence: MKPSIILYKTLPDDLLHRLEAHFTVTQVPNLHPETVARHAQAFASAQGLLGASETVNRALLEKMPALRAASTISVGYDNVEVDALTARKIVLMHTPAVLTETVADTVMALMLATARRVVDVAERVKAGEWTESIGPAWFGVDVHHKTLGIVGMGRIGMALAQRAHFGFTMPVLYHARRRHQEAEDRFNARYCDLDTLLQEADFVCVILPLTAETRHLFGATQFARMKSSAIFINAGRGPVVDENALIAALQNGEIYAAGLDVFEQEPLSVDSPLLNMSNVVAVPHIGSATHETRYNMMACAVDNLIDALQGKIEKNCVNPQAAG
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
What are the official names of this protein?
Glyoxylate/hydroxypyruvate reductase B.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRP1_HUMAN
Sequence: MALRGFCSADGSDPLWDWNVTWNTSNPDFTKCFQNTVLVWVPCFYLWACFPFYFLYLSRHDRGYIQMTPLNKTKTALGFLLWIVCWADLFYSFWERSRGIFLAPVFLVSPTLLGITMLLATFLIQLERRKGVQSSGIMLTFWLVALVCALAILRSKIMTALKEDAQVDLFRDITFYVYFSLLLIQLVLSCFSDRSPLFSETIHDPNPCPESSASFLSRITFWWITGLIVRGYRQPLEGSDLWSLNKEDTSEQVVPVLVKNWKKECAKTRKQPVKVVYSSKDPAQPKESSKVDANEEVEALIVKSPQKEWNPSLFKVLYKTFGPYFLMSFFFKAIHDLMMFSGPQILKLLIKFVNDTKAPDWQGYFYTVLLFVTACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPVNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLSAVGTFTWVCTPFLVALCTFAVYVTIDENNILDAQTAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRPVKDGGGTNSITVRNATFTWARSDPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGSVAYVPQQAWIQNDSLRENILFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARDGAFAEFLRTYASTEQEQDAEENGVTGVSGPGKEAKQMENGMLVTDSAGKQLQRQLSSSSSYSGDISRHHNSTAELQKAEAKKEETWKLMEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFMCNHVSALASNYWLSLWTDDPIVNGTQEHTKVRLSVYGALGISQGIAVFGYSMAVSIGGILASRCLHVDLLHSILRSPMSFFERTPSGNLVNRFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVILLATPIAAIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSSWPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLLQQRGLFYSMAKDAGLV
What is the function of this protein?
Mediates export of organic anions and drugs from the cytoplasm (PubMed:7961706, PubMed:16230346, PubMed:9281595, PubMed:10064732, PubMed:11114332).  Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics (PubMed:7961706, PubMed:16230346, PubMed:9281595, PubMed:10064732, PubMed:11114332).  Confers resistance to anticancer drugs by decreasing accumulation of drug in cells, and by mediating ATP- and GSH-dependent drug export (PubMed:9281595).  Hydrolyzes ATP with low efficiency (PubMed:16230346).  Catalyzes the export of sphingosine 1-phosphate from mast cells independently of their degranulation (PubMed:17050692).  Participates in inflammatory response by allowing export of leukotriene C4 from leukotriene C4-synthezing cells (By similarity).  Mediates ATP-dependent, GSH-independent cyclic GMP-AMP (cGAMP) export (PubMed:36070769).  Thus, by limiting intracellular cGAMP concentrations negatively regulates the cGAS-STING pathway (PubMed:36070769).
What are the official names of this protein?
Multidrug resistance-associated protein 1, ATP-binding cassette sub-family C member 1, Glutathione-S-conjugate-translocating ATPase ABCC1, Leukotriene C(4) transporter, LTC4 transporter.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MAD51_ORYSJ
Sequence: MARRGRVQLRRIEDKASRQVRFSKRRAGLFKKAFELALLCDVEVALLVFSPVGKLYEYSSSSIEGTYDRYQQFAGARRDLNEGSTSINSDENASIHSRLRDITAWSLQNNADESDANQLEKLEKLLTNALRDTKSKKMLAKQNGEGSRSRANSSGSRGQEEGSA
What is the function of this protein?
Probable transcription factor involved in the regulation of flowering time under short day (SD) conditions.  Functions as promoter of flowering under SD conditions, upstream of EHD1, HD3A and MADS14, but downstream of GIGANTEA (GI).  May transmit a SD promotion signal from GI to EHD1.  Functions independently of MADS50 to control flowering time.
What are the official names of this protein?
MADS-box transcription factor 51, OsMADS51, OsMADS65.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y4442_HALS3
Sequence: MRVIGTVGMPGSGKSEAATVAANAGIPVLVMGDVIRQECRDRGLDPAQHHGRIAQALRDEHGPGAIAHQSLPIIEDHLTDATTVLVDGIRSDVEVTTFRDAFGDDFTLVHVSAPRELRKARIEDRDRPGDTDGEPLDAREDRERGFGMDDAIDLADVRIENTDSLDAFHDAVRDLLAADTPHTEVPDNHD
What are the official names of this protein?
UPF0200 protein OE_4442F.
What is the protein family that this protein belongs to?
Belongs to the UPF0200 family.
Protein: RL22_AZOPC
Sequence: MGVRKRISAEKRKESRRTMYFARLRHIPVSARKVRLVADMIRGIEVFKALGILRFSNKKISLFLEKLLKLAISNWEQKTGRQAENGELFITMVNVDVSTILKRIRPAPQGRAHRVRKRFSHVVIFVNTKNEIQN
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: GATA_STRP1
Sequence: MSFNHKTIEELHDLLVAKEISATELTQATLEDIKSREEAVGSFITVSEEVALKQAAAIDAKGIDADNLMSGIPLAVKDNISTKEILTTAASKMLYNYEPIFNATSVANAYAKDMIVIGKTNMDEFAMGGSTETSYFKKTKNAWDHTKVPGGSSGGSATAVASGQVRLSLGSDTGGSIRQPAAFNSVVGLKPTYGTVSRYGLIAFGSSLDQIGPFAPTVKENAQLLNVIASSDVKDATSAPVRIADYTSKIGRDIKGMKIALPKEYLGEGIDPEIKETVLASVKQFEALGATVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGFRADDAKNLDEIYVNTRSQGFGDEVKRRIMLGTFSLSSGYYDAYFKKAGQVRTLIIQDFDKVFADYDLILGPTTPTVAFGLDTLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFVDGLPVGLQLIGPKYAEETIYQAAAAFEAVTDYHKQQPIIFGGDK
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: CAID_SALPK
Sequence: MSESLHLTRNGPILEITLDRPKANAIDAKTSFAMGEAFLNFRDDPELRVAIITGGGEKFFSAGWDLKAAAEGEAPDADFGPGGFAGLTEIFDLDKPVIAAVNGYAFGGGFELALAADFIVCAENASFALPEAKLGIVPDSGGVLRLPKLLPPAIVNEMVMTGRRMSAEEALRWGIVNRVVSQSELMDSARELAQQLVNSAPLAIAALKEIYRATSEMPVEEGYRYIRSGVLKHYPSVLHSEDALEGPQAFAEKRDPVWKGR
What is the function of this protein?
Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA.
What are the official names of this protein?
Carnitinyl-CoA dehydratase, Crotonobetainyl-CoA hydratase.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
Protein: PLXD1_HUMAN
Sequence: MAPRAAGGAPLSARAAAASPPPFQTPPRCPVPLLLLLLLGAARAGALEIQRRFPSPTPTNNFALDGAAGTVYLAAVNRLYQLSGANLSLEAEAAVGPVPDSPLCHAPQLPQASCEHPRRLTDNYNKILQLDPGQGLVVVCGSIYQGFCQLRRRGNISAVAVRFPPAAPPAEPVTVFPSMLNVAANHPNASTVGLVLPPAAGAGGSRLLVGATYTGYGSSFFPRNRSLEDHRFENTPEIAIRSLDTRGDLAKLFTFDLNPSDDNILKIKQGAKEQHKLGFVSAFLHPSDPPPGAQSYAYLALNSEARAGDKESQARSLLARICLPHGAGGDAKKLTESYIQLGLQCAGGAGRGDLYSRLVSVFPARERLFAVFERPQGSPAARAAPAALCAFRFADVRAAIRAARTACFVEPAPDVVAVLDSVVQGTGPACERKLNIQLQPEQLDCGAAHLQHPLSILQPLKATPVFRAPGLTSVAVASVNNYTAVFLGTVNGRLLKINLNESMQVVSRRVVTVAYGEPVHHVMQFDPADSGYLYLMTSHQMARVKVAACNVHSTCGDCVGAADAYCGWCALETRCTLQQDCTNSSQQHFWTSASEGPSRCPAMTVLPSEIDVRQEYPGMILQISGSLPSLSGMEMACDYGNNIRTVARVPGPAFGHQIAYCNLLPRDQFPPFPPNQDHVTVEMSVRVNGRNIVKANFTIYDCSRTAQVYPHTACTSCLSAQWPCFWCSQQHSCVSNQSRCEASPNPTSPQDCPRTLLSPLAPVPTGGSQNILVPLANTAFFQGAALECSFGLEEIFEAVWVNESVVRCDQVVLHTTRKSQVFPLSLQLKGRPARFLDSPEPMTVMVYNCAMGSPDCSQCLGREDLGHLCMWSDGCRLRGPLQPMAGTCPAPEIHAIEPLSGPLDGGTLLTIRGRNLGRRLSDVAHGVWIGGVACEPLPDRYTVSEEIVCVTGPAPGPLSGVVTVNASKEGKSRDRFSYVLPLVHSLEPTMGPKAGGTRITIHGNDLHVGSELQVLVNDTDPCTELMRTDTSIACTMPEGALPAPVPVCVRFERRGCVHGNLTFWYMQNPVITAISPRRSPVSGGRTITVAGERFHMVQNVSMAVHHIGREPTLCKVLNSTLITCPSPGALSNASAPVDFFINGRAYADEVAVAEELLDPEEAQRGSRFRLDYLPNPQFSTAKREKWIKHHPGEPLTLVIHKEQDSLGLQSHEYRVKIGQVSCDIQIVSDRIIHCSVNESLGAAVGQLPITIQVGNFNQTIATLQLGGSETAIIVSIVICSVLLLLSVVALFVFCTKSRRAERYWQKTLLQMEEMESQIREEIRKGFAELQTDMTDLTKELNRSQGIPFLEYKHFVTRTFFPKCSSLYEERYVLPSQTLNSQGSSQAQETHPLLGEWKIPESCRPNMEEGISLFSSLLNNKHFLIVFVHALEQQKDFAVRDRCSLASLLTIALHGKLEYYTSIMKELLVDLIDASAAKNPKLMLRRTESVVEKMLTNWMSICMYSCLRETVGEPFFLLLCAIKQQINKGSIDAITGKARYTLSEEWLLRENIEAKPRNLNVSFQGCGMDSLSVRAMDTDTLTQVKEKILEAFCKNVPYSQWPRAEDVDLEWFASSTQSYILRDLDDTSVVEDGRKKLNTLAHYKIPEGASLAMSLIDKKDNTLGRVKDLDTEKYFHLVLPTDELAEPKKSHRQSHRKKVLPEIYLTRLLSTKGTLQKFLDDLFKAILSIREDKPPLAVKYFFDFLEEQAEKRGISDPDTLHIWKTNSLPLRFWVNILKNPQFVFDIDKTDHIDACLSVIAQAFIDACSISDLQLGKDSPTNKLLYAKEIPEYRKIVQRYYKQIQDMTPLSEQEMNAHLAEESRKYQNEFNTNVAMAEIYKYAKRYRPQIMAALEANPTARRTQLQHKFEQVVALMEDNIYECYSEA
What is the function of this protein?
Cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E.  Plays an important role in cell-cell signaling, and in regulating the migration of a wide spectrum of cell types.  Regulates the migration of thymocytes in the medulla.  Regulates endothelial cell migration.  Plays an important role in ensuring the specificity of synapse formation.  Required for normal development of the heart and vasculature (By similarity).  Mediates anti-angiogenic signaling in response to SEMA3E.
What are the official names of this protein?
Plexin-D1.
What is the protein family that this protein belongs to?
Belongs to the plexin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Cell projection, lamellipodium membrane.