PharMolix/UniProtQA huggingface dataset:
Protein: TPS12_SOLLC
Sequence: MASSSANKCRPLANFHPTVWGYHFLSYTHEITNQEKVEVDEYKETIRKMLVEAPEGSEQKLVLIDAMQRLGVAYHFDNEIETSIQNIFDASSKQNDNDNNLYVVSLRFRLVRQQGHYMSSDVFKQFINQDGKFKETLTNDVQGLLSLYEASHLRVRDEEILEEALTFTTTHLESTVSNLSNNNSLKAEVTEAFSQPIRMTLPRVGARKYISIYENNDAHNHLLLKFAKLDFNMLQKLHQRELSDLTRWWKDLDFANKYPYARDRLVECYFWILGVYFEPKYSRARKMMTKVIQMASFFDDTFDAYATFDELEPFNNAIQRWDINAIDSVPPYLRHAYQALLDIYSEMEQALAKEFKSDRVYYAKYEMKKLVRAYFKEAQWLNNDNHIPKYEEHMENAMVSAGYMMGATTCLVGVEEFISKETFEWMINEPLIVRASSLIARAMDDIVGHEVEQQREHGASLIECYMKDYGVSKQEAYVKFQKEVTNGWMDINREFFCPDVEVPKFVLERVLNFTRVINTLYKEKDEYTNSKGKFKNMIISLLVESVEI
What is the function of this protein?
Sesquiterpene synthase involved in the biosynthesis of volatile compounds (PubMed:21813655, PubMed:20431087, PubMed:21818683).  Mediates the conversion of (2E,6E)-farnesyl diphosphate (FPP) into (1E,4E,8E)-alpha-humulene and (-)-(E)-beta-caryophyllene, and of (2Z,6Z)-farnesyl diphosphate ((ZZ)-FPP) into beta-bisabolene, gamma-curcumene and (Z)-gamma-bisabolene (PubMed:21813655, PubMed:20431087, PubMed:21818683).  Can act with a low efficiency as a monoterpene synthase with geranyl diphosphate (GPP) as substrate, thus producing beta-myrcene, (E)-beta-ocimene, limonene and terpinolene (PubMed:21818683).
What are the official names of this protein?
Sesquiterpene synthase 12, SlTPS12, Terpene synthase 12, (E)-beta-ocimene synthase TPS12, (Z)-gamma-bisabolene synthase TPS12, Alpha-humulene synthase TPS12, Beta bisabolene synthase TPS12, Beta caryophyllene synthase TPS12, Beta-myrcene synthase TPS12, Gamma-curcumene synthase TPS12, Limonene synthase TPS12, Terpinolene synthase TPS12.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsa subfamily.
Protein: ATPE_MYCTA
Sequence: MAELNVEIVAVDRNIWSGTAKFLFTRTTVGEIGILPRHIPLVAQLVDDAMVRVEREGEKDLRIAVDGGFLSVTEEGVSILAESAEFESEIDEAAAKQDSESDDPRIAARGRARLRAVGAID
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL20_WOLWR
Sequence: MARVKRGVTTHARHKKILKLAKGYRGRAKSCYRIALQRVEKALQYAYRDRRTRKRDFRSLWIIRINAAAREHGLTYGRFMHGLTLAGIDLNRKILAEMAVNYKDDFAKLVETVSGKLAENS
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: RS10_SYNE7
Sequence: MATLQQQKIRIRLKAFDRRLLDTSCDRIVETANRTNATAIGPIPLPTRRRIYCVLRSPHVDKDSREHFETRTHRRIIDIYQPSSKTIDALMKLDLPAGVDIEVKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RL23_CHLPD
Sequence: MKNPLLRPWLTEKSTGLTEKKGQYVFKVKLDADKTDIKKAIEEKFGVVVKSVRTVNCLGKSKRQFTRKGVLQGKKSDWKKAIVTLAKDQSIDYYSGSTQKGEG
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: CDPAS_PYRHO
Sequence: MKMNQLLEAFWYILPAYFANSSPVVLGGGTPIDFGKKWRDGRRILGDGKTWRGFFGGLIVGTIIGIVQYFLLPEYYGSLGIAIELAFLLSLGTLVGDLIGSFIKRRLNMPRGYPAVGLDQWGFLIAALCFAYPVKTIPTGEVLFLLVITPLIHWGANIFAYKMGWKKVPW
What is the function of this protein?
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP.  This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
CDP-archaeol synthase, CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-archaeol synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EAF3_KLULA
Sequence: MAIVLDGKCLCYHGPLLYEAKVLRVYDEKNQTITSKDYKDVSIDDEKVEFDRPPEHMRQGQCYFVHYQGWKSSWDEWVGLDRIRPYNDENLELKKSLVEKARELKNNGGKKKSGSRPVGRPSKVEKGKKAASRTSNSGSGTNTSASSTSASNPASSSSSGTTAAASSSDKSDRKKATPVLNKRSHPKIHIKVPISLRSVLVDDWENVTKDRKLVQLPSERPIEHILSQFYADTSNSTSSVVEQAQLSEFLQGIKLYFNLSLGKLLLYRLERIQYAELLKAHSEKQYTEIYGIIHLLRLVTLLPEMMESSNVDDQTAKILVKQCDILLEWIAINIARKNFPVDPYINTSSQYEGVALSM
What is the function of this protein?
Involved in deacetylation of histones, chromatin assembly and chromosome segregation.  May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains.  Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A.  The NuA4 complex is also involved in DNA repair (By similarity).
What are the official names of this protein?
Chromatin modification-related protein EAF3.
What is the protein family that this protein belongs to?
Belongs to the MRG family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPOZ_ECOSM
Sequence: MARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPEENDKTTVIALREIEEGLINNQILDVRERQEQQEQEAAELQAVTAIAEGRR
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: MCFS_DICDI
Sequence: MSTERGLKDSIAGTVAGAACLFTGHPFDTIRVRLQTSNTPIGIMECFRNTIKYEGFSGLYKGVTSPLFGMMFETAVLFAGYGQMKVLLQKDENTPLTVGQCAIAGGFAGVGASVVLTPVELVKCRLQVQTTGPQKYKGSLDCLVQILKEGGIRGAYRGFTPTIAREFVGNMAFFSTYETCKRYFKNKENKPNDDDELNLPALIISGGLGGMAYWTVLYPVDVAKSKIQISEGAGPSPSIVKVLKEIYSKEGVKGLFRGYTPTIIRSFPANAAMFSVYELVIKLLG
What is the function of this protein?
Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane.  Mediates the transport of acylcarnitines of different length across the mitochondrial inner membrane from the cytosol to the mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway (By similarity).
What are the official names of this protein?
Mitochondrial substrate carrier family protein S, Carnitine/acylcarnitine translocase, CAC, Solute carrier family 25 member 20 homolog B.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CCPA_NOVHA
Sequence: MSASGSDEVAGGGQAGSPQDFQRVLRSFGVEGGQYSYRPFVDRSFDVTGVPEAVERHFDQAEHDTAVEEQVTPAPQIAVAPPPPPVVPDPPAIVTETAPPPPVVVSAPVTYEPPAAAVPAEPPVQEAPVQAAPVPPAPVPPIAEQAPPAAPDPASVPYANVAAAPVPPDPAPVTPAPQARVTGPNTRMVEPFSRPQVRTVQEGATPSRVPSRSMNAFPRTSASSISERPVDRGVADEWSPVPKARLSPRERPRPGDLSFFFQGMRDTRDEKKFFPVASTRSVRSNVSRMTSMTKTDTNSSQASRPGSPVASPDGSPTMAEVFMTLGGRATELLSPRPSLREALLRRRENEEES
What are the official names of this protein?
Cellulose-complementing protein.
Protein: TOP3B_DROME
Sequence: MKSVLMVAEKPSLAASLAGILSNGRCTAKRGTGNGCSTHEWTGNFRNEGSVHFRMTSVCGHVMSLDFNKKYNCWDKVDPIQLFGCATEKKETNPKQNMRKFLAHEARGCDYLVLWLDCDKEGENICFEVMDAVKHVINNVYSDQVTYRAHFSAITEKDIKKAMETLGHPNENEAKSVDARQELDLRIGCAFTRFQTKFFQDRYGDLDSSLISYGPCQTPTLGFCVKRHDDIQTFKPESFWHLQLLAGQPEVTLEWARGRVFKKDIAIMLLNRVKEHKKATVESVASKEAYKSKPQALNTVELMRICSSGLGIGPFQAMQIAERLYTQGYISYPRTETNQYPTNFDLPAVLHVLKPSADFGEEARSILGDIQTPRKGKDAGDHPPITPMKLGNRSDFDRDTWRVYEFICRHFMGTVSRDLKYRVTTAKLSVGMETFSCTASVLIDAGFTKVMTWSAFGKDEPQPPFVQGTQVAINDVRLIESQTGPPDYLTESELITLMEEHGIGTDASIPVHINNICQRNYVHIENGRKLMPTTLGIVLVHGYQKIDPELVLPTMRTEVERMLTLIAQGSANFQDVLRHAIKIFKLKFMYFVKNIDSMDALFEVSFSPLAESGKAHSRCGKCRRYMKYIQTKPARLHCSHCDETYALPIGNVKVYREFKCPLDDFDLLAFSTGVKGRSYPFCPYCYNHPPFSDMPHLGGCNTCTNANCPHSLNTLGISSCVECPTGVLVLDCTLAPTWKLGCNRCDVIINCFKGATKITVEEAKCQECGAQQVNVVYKSDKSKFKDGSEEKSGCIFCSADFSHLVEKHRAVASRPVRSGGGFRGGKAGRGGGGMGGAAFGSGGAVTAGGGPNAGGGVRGSRVAKDKMGQLASYFV
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.  The free DNA strand than undergoes passage around the unbroken strand thus removing DNA supercoils.  Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity).  Weakly relaxes negative supercoils and displays a distinct preference for binding single-stranded DNA.
What are the official names of this protein?
DNA topoisomerase 3-beta, DNA topoisomerase III beta.
What is the protein family that this protein belongs to?
Belongs to the type IA topoisomerase family.
Protein: Y1003_BACVZ
Sequence: MAVHFYDAAYDLEKALRNSDEYSRLRGLYDQVNADESAKRMFDNFRNVQLQLQQKQMSGEEITQEEVEQAQKTVALVQQHELISQLMEAEQRMSMLIGELNKIIMKPLEELYGSQQ
What are the official names of this protein?
UPF0342 protein RBAM_010030.
What is the protein family that this protein belongs to?
Belongs to the UPF0342 family.
Protein: RL28_BIFLD
Sequence: MAARCAVCGKGPQTGFTVSHSHRRTKRSFRPNLQSVRTTIDGENTRLRVCVKCLKAGKVQRVAA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: Y1931_DICDI
Sequence: MNKKFIFILLIVFICFLNISQSIRINNNKNNNINNNYNNNNNNNIQTKEKRERNLIKFKEIEKIRKFLGNVESLTTIPLVSNEKIILEKLYSDWNGKDWDDNTNWLNGDPCMNQWYGIECNSFDGGITNNVISIKMSLNNIVGEMSTEIKNLVHLQTLDISNNGFYGEIPIGIFQQMNNLSYISLNENEFQGDLEWASYLPDSIVTLWIAMNQFQGTIPTFFSKYPILDLLFLEENLLIGTIPPEVGDLKKIKLLDFGLNTITGTLPSSIGNLSYLEQFWLYDNQLEGSIPLTMGNLQNLKLFEVTRNQLGGDLSGVFLNNPNLKSLRFSGNSFYGDLDWICQLDGLRDVHFDINRFESLPNCLGKAPLQMNELLLADNLISGTIPSSIGNMIGIEYINLARNNLTGTIPSSFNNFSNLNRIDISSNKFNCSLSEILDPIKHQTHLTIISAQYNEIHGEFFENMVWDGVQQIELLTKIFIINLSHNKLSGPIPEYLSWMPNLNDLDLSYNNLSGTVPNQLSFLSTMYLENNPFLGSSDGSLPLFMEPSVIFIHKDTESYACPSIIGKGFDIRISLDSTYYNNSFCLCDYNYRGVNGSCKICPQDSYCPGGGNDILIPSGYYPMPSNENPEYLLKCIISNFGYTSCNPDSSYNYTCQDGYQGRLCSKCVDGYFHKGTECSVCPTGPQSIVIFIVVVVVFIALFLFFVMTDPKRSLPSSTRKTVMYYYQVFNLLLSKLSPWPSFFSIFYSGSSWLNFSFGFLCINNLSRWPNLFIVMICLPFAFLVISIVFIASMQLFHYVKSSLNGVDYIFNKKLIYSGVRVNLLALNFLYLPLCIYIFQNYPCTKDQVTGESFMSFFPWQECGDNSTHNRIMRLTIAFTIIYVIGIPLLFAILLFYNRKRLDNPMILTMIGSIYIDYRKSVYWYELVALGRRFFMAVSLALIDPKSSFSIFVVLLVIGSSIISQIIFKPYVYRISNYSETIGNSVLLFSYVCILILSSLATTKLYDSQGIEIILSVVVVVYTVLLLLLFLFSLKYFLPKKWQTVIDYHIIKFITWVRITSNNLISDIKDINSIDGDDSFETTKEPIFERTVSNNLNVLGSFELKRRNSQINSNCNNNNNNNNNNNNNNNNNNNNNNNNINNNIISAKQLDCNNNNNNYNGEKITPGDGQDCLISLSIDNSGTNFNHNNDNNNNDDNNDNNINNNEEFNKNN
What are the official names of this protein?
Putative leucine-rich repeat-containing protein DDB_G0281931.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PPAC_BACHK
Sequence: MEKVLVFGHKNPDTDAICSAIAYAELKKELGMNAEPVRLGEISGETQFALDYFKVEGPRFVETVANEVDNVILVDHNERQQSANDIESVRVLEVIDHHRIANFETSDPIYYRCEPVGCTATILNKMYKENGVTIRKEVAGLMLSAIISDSLLFKSPTCTEQDVAAARELAEIAGVDADKYGLEMLKAGADLSGKTMEQLISLDAKEFQMGNAKVEIAQVNAVDTNDVLVHQAELEKVISAVVEEKGLDLFLFVVTDILTNDSVGLAIGKAANIVEKAYNVSLENNTATLKGVVSRKKQIVPVLTEAFQA
What are the official names of this protein?
Probable manganese-dependent inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase class C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YP57_BRUA2
Sequence: MRTLVMVACAVSLAACSSPPKPPTVSGRHRIPINSPAAQEELRLQVFPQEPTAQATMWPARPPKQTVNVYFPQDVTVFRPTSAQINQLHTLLWPVPKHINVRGLTDNNCPPPGDTQVARVRALAIYNWLINQGVPASRITISYAPVKDYASNAPLSPGRVLNRRVDIEILRK
What is the function of this protein?
The virB operon is essential for intracellular survival and is not involved in the invasion process.  Constitutes a major determinant of virulence in mice.  This protein is essential for pathogenesis in mice but is not required for intracellular survival.
What are the official names of this protein?
Type IV secretion system putative outer membrane lipoprotein BAB2_0057.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: Y1700_STAA9
Sequence: MMDNKDYKKFYLIREDVLPESVVKTLKIKDALKSDPTLSIYDAVKQFDLSRSAFYKYRETIFPVDDKMLDHREFTLILYVTDIVGMLARVLDVISKLELSVLTIHQSIPMEEKATITLSLNAKSKETSVEDVIGALRNLDYVSKVELISMSM
What are the official names of this protein?
UPF0735 ACT domain-containing protein SaurJH9_1700.
What is the protein family that this protein belongs to?
Belongs to the UPF0735 family.
Protein: MET3_CRYNH
Sequence: MANAPHGGVLKDLLVRDAALHDSLLEEARSLNDIFLTERQLCDLELILNGGFSPLEGFMDEQDYTSVVETLRLAPFNGHKYGHVFPIPITLDVSQEDINTLGLKQGARVALRDPRDDAALAILTVSDIYRPNKATEAEKVMGADDIAHPSVAYLRNNVKEFYVGGKVQAIQAPTHFDYVPLRYTPAELRAHFHKLAWRKVVAFQTRNPMHRAHRELTVRAARQRRANVLIHPVVGLTKPGDVDHYTRVRAYQALMPSYPEGMAHLALLPLAMRMAGPREAVWHAVIRKNFGATHFIVGRDHAGPGKNSQGKDFYGPYDAQELVTQFKDELQIEMVPFQAMTYLPGSDEYQPVDEVPKGTPTADISGTELRKRLRTGASIPDWFSYTGVVKVLRESYPPRPQQGFTILLTGLHNSGKDTIARALQVTLQQQGSRSVSLLLGEELRSDLDPQIGRAITPEQKHINLERIGFVAAELTKAGAAVIAAPTAPYERSRQAFKKQVVGSGGGNYFLVHVATPLEWCEKVDRRGLYKAARAGEIKNLTGVDDVYEAPENADLVCDLRIDTVPEIVHSIIMILESQNLV
What is the function of this protein?
Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP.  Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids.
What are the official names of this protein?
Sulfate adenylyltransferase, ATP-sulfurylase, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the APS kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_AZOC5
Sequence: MAKEAARVKRRERKNIASGVAHVNASFNNTMITITDAQGNTISWSSAGAMGFKGSRKSTPYAAQLAAEDAARKAAEHGMRTLEVEVSGPGSGRESALRALQAAGFLVTSIRDVTPIPHNGCRPRKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: HACD2_BOVIN
Sequence: MAAAAAIAASKGNGGGGGRAGAGEASSSRRKKGPGPLTTAYLVIYNVVMTAGWLVIAVGLVRAYLAKGSYHSLYYSIEKPLKFFQTGALLEILHCAIGIVPSSVVLTSIQVMSRVFLIWAVTHSVKEVQSEDSVLLFVIAWTITEIIRYSFYTFSLLNHLPYLIKWARYTLFIVLYPMGVSGELLTIYAALPFVRQAGLYSISLPNKYNFSFDYYAFLILIMISYIPLFPQLYFHMIHQRRKILSHTEEHKKFE
What is the function of this protein?
Catalyzes the third of the very long-chain fatty acids (VLCFA) elongation four-step cycle (condensation, reduction, dehydration, and reduction).  This endoplasmic reticulum-elongation process is characterized by the addition of two carbons to the lipid chain through each cycle.  This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of elongation.  Therefore, it participates in the production of various VLCFAs involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
What are the official names of this protein?
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2, 3-hydroxyacyl-CoA dehydratase 2, HACD2, Protein-tyrosine phosphatase-like member B.
What is the protein family that this protein belongs to?
Belongs to the very long-chain fatty acids dehydratase HACD family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MMP12_MOUSE
Sequence: MSCTLLKGVCTMKFLMMIVFLQVSACGAAPMNDSEFAEWYLSRFYDYGKDRIPMTKTKTNRNFLKEKLQEMQQFFGLEATGQLDNSTLAIMHIPRCGVPDVQHLRAVPQRSRWMKRYLTYRIYNYTPDMKREDVDYIFQKAFQVWSDVTPLRFRKLHKDEADIMILFAFGAHGDFNYFDGKGGTLAHAFYPGPGIQGDAHFDEAETWTKSFQGTNLFLVAVHELGHSLGLQHSNNPKSIMYPTYRYLNPSTFRLSADDIRNIQSLYGAPVKPPSLTKPSSPPSTFCHQSLSFDAVTTVGEKIFFFKDWFFWWKLPGSPATNITSISSIWPSIPSGIQAAYEIESRNQLFLFKDEKYWLINNLVPEPHYPRSIYSLGFSASVKKVDAAVFDPLRQKVYFFVDKHYWRYDVRQELMDPAYPKLISTHFPGIKPKIDAVLYFKRHYYIFQGAYQLEYDPLFRRVTKTLKSTSWFGC
What is the function of this protein?
May be involved in tissue injury and remodeling.  Has significant elastolytic activity.  Can accept large and small amino acids at the P1' site, but has a preference for leucine.  Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3 (By similarity).
What are the official names of this protein?
Macrophage metalloelastase, MME, Matrix metalloproteinase-12, MMP-12.
What is the protein family that this protein belongs to?
Belongs to the peptidase M10A family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: DENR_YARLI
Sequence: MTEVVPRTVLYCGVCTLPPEYCEFGGAFKRCKAWLEDNDQELFAQLYSVEALTNAVQASSISAEKQEEIDRKLQKQQQKDEAKAERELLKKLASKVVIKRIERSKRKRIISVSGLEVFELDLKKLSKTFSSKFATGASVTKTADGKEEIVIQGDVGDGVEELITQMLKEKGLNQVKVEQIDEKKKKKE
What are the official names of this protein?
Translation machinery-associated protein 22.
What is the protein family that this protein belongs to?
Belongs to the DENR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUT_RHILW
Sequence: MTIHHDLRPTLNLIRLANGEGLDLPAYESKGAAGMDLRAAVDEAAPLTLQPGKRALVPTGFIFEIPEGFEGQVRPRSGLAFKHGITCLNSPGTVDSDYRGEVKVLLANLGDEAFTVERGMRIAQMVIAPVTQMRVAESAAASETTRGAGGFGSTGV
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: SUCC_WOLPM
Sequence: MNIHEYQAKEVFHKFNVPVPKGFVATSAEEVKTQVSQLKSDVFVVKAQIHAGGRGKAGGVKLAKSVEEAQQFVKDMIGMTLVTHQTGPSGQQVRKVYVEEGSSIKKEYYLSLVIDPKLSRPIFIFSSEGGMDIEEVAKNSPAKIVKFDIDPATSFDSSKLSSRFHLSPEQIEKISNIAKKIYDAFIATDASQIEINPLVETNSGDFIALDAKINFDDNALYRHPEIMELRDYDEEVKEEIEASKYGLSYIKMDGSIGCMVNGAGLAMATMDIIKYYGAEPANFLDVGGGASKETVTEAFKIILSDSNVKGILVNIFGGIMRCDIIASGIVAAAKEMSIKVPLVVRLSGTNFEEGKKILEESGLNIIAADELDEAAQKIVKEVK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: RS14_CUPNH
Sequence: MAKLALIEREKKRAKLVAKYAAKRANLKAIIDDQEKSEEERYSARLELQQLPRNANPTRQRNRCAITGRPRGTFRKFGLARNKIREIAFKGEIPGLTKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: BIOH_CHRVO
Sequence: MNLFVETLGQGPDVVMLHGWGLHGGVFARVAEQLATRFCVHLVDLPGHGASPALPRFDADAVADLLAAHFPLPAQVVGWSLGGLIAQHWAARHPDKVKSLALVATSPRFVRDETWPHAQARASIEAVAQSLDGAFEQTLERFLALQMMGAPSARDTLKALRGELFSHGRPQGLLPALGLLLEADARALAGRIQCPAALFYGARDAITPIGAGRWLAESLPDAVLYEFPQASHAPFLSHEQDFVRALAEHLETQA
What is the function of this protein?
The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete.  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.
What are the official names of this protein?
Pimeloyl-[acyl-carrier protein] methyl ester esterase, Biotin synthesis protein BioH, Carboxylesterase BioH.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_GLUDA
Sequence: MAKATKPADLRAKTAEELEALLIDLKREQFNLRFQRATGQNEGQARVRTVRREIARVKTIASQALKKNAVGAGAPAAKS
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: BTUF_PECCP
Sequence: MIVRFLCWLTGLLLCTAAYALPQRVISLAPHATEMAYAAGMGEQLIAVSAWSDYPPEAKKLEQVASWQGINLERILALKPDLILAWREGNPQRPLEQLANFSIPIVYLDAKTLDDIPASLRQLATYSRHPEQAERAATDFQQEIGRLRHTGEGQNAASLRVFIQFGTQPLFTSSQATLQSQIVSLCGAENIFSDSPVPWPQVSREQVLRRQPQAIIIGGSPDKIASVQTFWQPQLAVPVITVNEDWFSRSGPRLLLAAQQICSQLTALSPGSSSAK
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Binds vitamin B12 and delivers it to the periplasmic surface of BtuC.
What are the official names of this protein?
Vitamin B12-binding protein.
What is the protein family that this protein belongs to?
Belongs to the BtuF family.
What are the subcellular locations of this protein?
Periplasm.
Protein: TRMFO_RUEPO
Sequence: MTDRLHIVGGGMAGSEAAWQAAQQGIDVVIHEMRPTVGTFAHQTGNLAEMVCSNSFRSDDDEQNAVGLLHWEMRAAGGLIMSAADAHRLPAGGALAVDRDPFAETVTARLHAHPRVSVTAEEVTELPRDGHWIFATGPLTSPALGAAIQAETGAEALAFFDAIAPIVYADTIDMSRAWMQSRYDKGETEEERTAYLNCPMDRDQYEAFIDALLAADKTEFHEGETATYFDGCLPIEVMAERGRETLRHGPMKPVGLTNPHQPDVKAYAVVQLRRDNALGTLYNIVGFQTKMKYGAQTAVFKTIPGLENASFARLGGIHRNTFLNSPTLLDAQMRMKSRPNIRFAGQITGVEGYVESAAMGLLAGRLAAAEIQGRALPEVPQDSAMGALIHHITGGAEAKTFQPMNVNFGLFRPVDGLKGGRRGRKDRYKAYTDRAKEAWTSWLAEAENG
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.