PharMolix/UniProtQA huggingface dataset:
Protein: THII_STRP7
Sequence: MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVTADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMRDIYKEGMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAYLSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPGALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIREVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTFDISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAEKDEVDDLIDNLL
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIB_ARATH
Sequence: MNMSDLGWDDEDKSVVSAVLGHLASDFLRANSNSNQNLFLVMGTDDTLNKKLSSLVDWPNSENFSWNYAIFWQQTMSRSGQQVLGWGDGCCREPNEEEESKVVRSYNFNNMGAEEETWQDMRKRVLQKLHRLFGGSDEDNYALSLEKVTATEIFFLASMYFFFNHGEGGPGRCYSSGKHVWLSDAVNSESDYCFRSFMAKSAGIRTIVMVPTDAGVLELGSVWSLPENIGLVKSVQALFMRRVTQPVMVTSNTNMTGGIHKLFGQDLSGAHAYPKKLEVRRNLDERFTPQSWEGYNNNKGPTFGYTPQRDDVKVLENVNMVVDNNNYKTQIEFAGSSVAASSNPSTNTQQEKSESCTEKRPVSLLAGAGIVSVVDEKRPRKRGRKPANGREEPLNHVEAERQRREKLNQRFYALRSVVPNISKMDKASLLGDAISYIKELQEKVKIMEDERVGTDKSLSESNTITVEESPEVDIQAMNEEVVVRVISPLDSHPASRIIQAMRNSNVSLMEAKLSLAEDTMFHTFVIKSNNGSDPLTKEKLIAAFYPETSSTQPPLPSSSSQVSGDI
What is the function of this protein?
Transcription activator.  Regulates positively abscisic acid (ABA) response.  Confers drought tolerance and sensitivity to ABA.
What are the official names of this protein?
Transcription factor ABA-INDUCIBLE bHLH-TYPE, AtAIB, Basic helix-loop-helix protein 17, AtbHLH17, bHLH 17, Transcription factor EN 35, bHLH transcription factor bHLH017.
What are the subcellular locations of this protein?
Nucleus.
Protein: THIG_PROMM
Sequence: MVLTHSSPDLLTIGKRNFHSRLFAGTGKYPSLKVMQESLRSSGCEMVTVAVRRVQTMASGHAGLIEAIDWSKIWMLPNTAGCATAEEAIRVARLGRELAKLAGQEDNKFVKLEVIPDSRYLLPDPFGTLEAAEQLVKEGFEVLPYINADPLLAKRLEEVGCATVMPLGSPIGSGQGLRNAANISLIIENARVPVVVDAGIGVPSEAAQALEMGADAVLVNSAIALAGDPITMAEAMRWAIQAGRQAYRSGRLPERAAASPSSPTTGIIAEAKTK
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POLC7_PHLPR
Sequence: MADDMERIFKRFDTNGDGKISLSELTDALRTLGSTSADEVQRMMAEIDTDGDGFIDFNEFISFCNANPGLMKDVAKVF
What is the function of this protein?
May be involved in the regulation of pollen-tube growth.
What are the official names of this protein?
Polcalcin Phl p 7, Calcium-binding pollen allergen Phl p 7, Protein P7.
Protein: HPPA_CARHZ
Sequence: MENGMTLAYYGLGAGILAILFALYLFSSVLKEDMGNEKMREISQAIFEGAMAYLNRQYKTLIPFALVVFVLLVVGFGYKEGDFGYGLKVGVSFLVGAIASALAGYAGMTSTTKANARTTQAARKSLNAALNVAFRAGGVMGMSVAGLGLLGVSALYIIFKDVHVIDSFAFGASAIAFFARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDTAGMGADLFESYGATTMAAMLLGLTFAKNHGFSEVLGATFPLLLGAAGIVAAIISTFFVRTSEDGNPQMALNIGLWSTNFITAIFTYIIAQYVFGSEWAPKIFIAVVSGLVVNVAIGSLTEYYTSNLKPPAQKIAEASTTGPATNIISGIAVGMRSTYLPIIVIVAAIMVGYWAAGFYGIALAAMGMLATAAMVVAVDSFGPVADNAGGIAEMAELGPEIRNKTDKLDAVGNTTAAVAKGFAIGSAALTALALFSAYTDLAKTNPNLQKYLVNGKFDLNITDPWVLVGLFLGGTVAFLVAALTMESVGKAAFDMIEEVRRQFREIPGLMEGKARPDYARCVSISTAAAIRQMIAPGLLAVGAPLAIGFILGFKALTGYLAGVTATGVLLAIYMANAGGAWDNAKKYIEAGNLGGKGSDTHKAAVVGDTVGDPFKDTSGPAMNPLMKVAGTFALIIVPLLLF
What is the function of this protein?
Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.
What are the official names of this protein?
K(+)-stimulated pyrophosphate-energized proton pump, Membrane-bound proton-translocating pyrophosphatase, Pyrophosphate-energized inorganic pyrophosphatase, H(+)-PPase.
What is the protein family that this protein belongs to?
Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LEU3_GEOMG
Sequence: MSQVFKVAVLPGDGIGPEVMAEALRVLDAIEKKYDVKFERTHANVGGAGIDLEGKALPETTITICKTSDAILFGSVGGPKWETLPPDEQPERGALLPLRKIFGLYANLRPAIIFPSLTGASSLKEEVIAGGFNVLVIRELTGGIYFAQPKGIEGEGRDRVGFDTMRYSVPEIERITHVAFQAARKRGKKVCSIDKANVLSSSVLWREVVTGIAKEYPDVELSHMYVDNAAMQLVRWPKQFDVILCENMFGDILSDEAAMLTGSLGMLPSASLAEGTFGMYEPSGGSAPDIAGQGIANPIAQILSMGMMLRFSFGMVDAADAIDNAVAKVLDQGCRTRDIFQEKPGEKLVNTKEMGDAIIVAL
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_PHEZH
Sequence: MTKLNELAPREGSTKNRMRVGRGPGSGKGKTAGRGVKGQKARTGVSIAGFEGGQMPLHMRMPKRGFNSRNRKDFAEVNLWRIEQAIAAGKLDAKAAIDAEALLKAGVIRRAKDGVKLLGKGELKSKLNLTVYSATASARAAVEKAGGKLTTTKPEAAQDASAEA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: Y387_CROS8
Sequence: MSAVSKTVDGLVLRLYIQPKASRDSIIGLHGDELKVAITAPPVDGQANAHLVKYLAKQFRVAKSQVVIEKGELGRHKQVKIIEPQQIPTEVAAVTD
What are the official names of this protein?
UPF0235 protein ESA_00387.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: Y1415_STRR6
Sequence: MKLAVFTDSSAYLSAETLQREDLFVLDIPVNIDGEEYVEGINLSAEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQSIQYMVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIMVDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEIIKETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIALGYIPVI
What is the function of this protein?
May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.
What are the official names of this protein?
DegV domain-containing protein spr1415.
Protein: RIBB_SHIDS
Sequence: MNQTLLSSFGTPFERVENALAALREGRGVMVLDDEDRENEGDMIFPAETMTVEQMALTIRHGSGIVCLCITEDRRKQLDLPMMVENNTSAYGTGFTVTIEAAEGVTTGVSAADRITTVRAAIADGAKPSDLNRPGHVFPLRAQAGGVLTRGGHTEATIDLMTLAGFKPAGVLCELTNDDGTMARAPECIEFANKHNMALVTIEDLVAYRQAHERKAS
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: SYY_PSEPF
Sequence: MKSVEEQLALIKRGAEELLVESELIEKLKRGQPLRIKAGFDPTAPDLHLGHTVLINKLRQFQELGHQVIFLIGDFTGMIGDPSGKSATRPPLTREQVLENAETYKTQVFKILDPAKTEVAFNSTWMDQMGPADFIRLTSQYTVARMLERDDFDKRYTTNQPIAIHEFLYPLVQGYDSVALRADVELGGTDQKFNLLMGRELQRGYGQEAQCILTMPLLEGLDGVKKMSKSLGNYVGIQEAPGVMYSKLVSIPDALMWRYFELLSFRSMDEINAFRADVEAGANPRDIKIKLAEEIVARFHGEEAAANAHRGAGNRMKDGELPDDLPEVELTAAEDMPIAAVLNKAGLVKNSAAARDLLASGGVRVDGEVVDRSFIYVLGATHVCQAGKKAFARITLKSE
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_MYCSK
Sequence: MPNPLPLVFDAPRRAKPPRHFADLDATARAAAVAELGLPAFRAKQLATQYYGRLTADPQQMTDLPAAVREQVAEALFPDLLTAVREIETDAGETRKVLWRAVDGTTFESVLMRYSDRNTVCISSQAGCGMACPFCATGQGGLQRNLSTAEILEQVRAAAVELRDRDGEGIAPAARGGRLSNIVFMGMGEPLANYNRVIAAVRRIVAPPPDGFGISARSVTVSTVGLAPAIRKLADERLNVTLALSLHAPDDELRDTLVPVNNRWKVSEALDAARYYADVTGRRVSIEYALIRDVNDQPWRADLLGKRLHGALGPLVHVNVIPLNPTPGSEWDASPKPAEREFVRRVRERGVSCTVRDTRGREIAAACGQLAAEG
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WHIA_MYCVP
Sequence: MAMTAEVKDELSRLVVNSVSARRAEVASLLRFAGGLHIVSGRVVVEAEVDLGIIARRLRKDIYDLYGYNAVVHVLSASGIRKSTRYVVRVAKDGEALARQTGLLDLRGRPVRGLPAQVVGGSVGDAEAAWRGAFLAHGSLTEPGRSSALEVSCPGPEAALALVGAARRLGVSAKAREVRGSDRVVVRDGEAIGALLTRMGAQDTRLTWEERRMRREVRATANRLANFDDANLRRSARAAVAAAARVERALQILGDTVPDHLAAAGNLRVAHRQASLEELGRLADPPMTKDAVAGRIRRLLSMADRKAKQDGIPDTESAVTPDLLEDA
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: AKTR2_ALTAL
Sequence: MLQCAPKKNERLRGSCDFCTQSKLRCNKNKPSCRRCTIQQQVCVYSVARRTGRPPKHPRRADDSQETSGQHGHQDPMTSAPADSCEQQSSHLDLEGDDTDFTLVDGRTTAEGRATVAPPVLDNAFLMGETFEFNSLLDDPLVQSEDIFSFSPHIPRGEKGVHMASFHALNESTSPCSPSALLSIDVPQLPTNFRFLESFIGSELHGRNEPHPVEQPDEMEKTYDKGSILLGLDSAINAITNNGKDEPSISGWTVARPHSKHLCFCSMSMSKLQVLVSHPALCRQNSRTPFDMVLFLEEFVFGIHSDVLRCLICQSRSLHSLASLCICTDWVVEALVDVAQDLSLGQDNLGGLRAEICPPKNGSSIYVGRLILADQFRESCTRSLVKYRLRKLIPIMDTMIKLNYRGAGGALSQAIRTMVEDVRHKIESALGMMEL
What is the function of this protein?
Transcription factor that regulates the expression of the gene clusters that mediate the biosynthesis of the host-selective toxins (HSTs) AK-toxins responsible for Japanese pear black spot disease by the Japanese pear pathotype (Probable).  AK-toxins are esters of 9,10-epoxy 8-hydroxy 9-methyldecatrienoic acid (EDA) (PubMed:22846083).  On cellular level, AK-toxins affect plasma membrane of susceptible cells and cause a sudden increase in loss of K(+) after a few minutes of toxin treatment (PubMed:22846083).
What are the official names of this protein?
Transcription activator AKTR-2, AK-toxin biosynthesis regulator 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: ORN_MANSM
Sequence: MQLDNQNLIWIDLEMTGLDPENERIIEIATIVTDKDLNILAEGPVLAVHQSDELLAKMSDWCIKTHSANGLVDRVKASKLTERAAELQTIDFLKKWVPKGASPICGNSVAQDKRFLFKYMPELADYFHYRHLDVSTLKELARRWKPELLNGFEKKNTHLALDDIRESIAELAYYRDHFIKLDGDQK
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIFB_SINFN
Sequence: MSAPIISLESLTNTTSSGQLLTTAKSGGCASSSCGSSSRPTDMDSATWEKIKDHPCFSEEAHHYFARMHVAVAPACNIQCNYCNRKYDCANESRPGVVSEKLTPDQALRKVVAVANEVPQLSVLGIAGPGDACYDWNKTRATFERVASEIPDIKLCISTNGLALPEHVDKLAEMNVSHVTITINMVDPAVGEKIYPWIFYGHRRYTGVDAAKILHEQQMLGLEMLTARGILTKINSVMIPGVNDLHLIEVNKWVKERGAFLHNVMPLISDPAHGTSFGLTGQRGPNALELKALHDRLEGGAKLMRHCRQCRADAVGLLGTDRGQEFTLDHVPLEPHYDGAKRQAYREVVARIRDDHLEAKEKAIATVASANIRGSLQVAVATKGGGRINEHFGHAKEFQVYEASQTGIKFVGHRKVEPYCHGGWGEDAALAGIIAALDGIDIVLCARIGDCPKERLMEAGIRATDTYGYDYIEAAISALHATEFGTAPSQATA
What is the function of this protein?
Involved in the biosynthesis of the iron-molybdenum cofactor (FeMo-co or M-cluster) found in the dinitrogenase enzyme of the nitrogenase complex in nitrogen-fixing microorganisms.  NifB catalyzes the crucial step of radical SAM-dependent carbide insertion that occurs concomitant with the insertion of a 9th sulfur and the rearrangement/coupling of two [4Fe-4S] clusters into a [8Fe-9S-C] cluster, the precursor to the M-cluster.
What are the official names of this protein?
FeMo cofactor biosynthesis protein NifB, Nitrogenase cofactor maturase NifB, Radical SAM assemblase NifB.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. NifB family.
Protein: G6PI_PSEPW
Sequence: MAYYRTPHDVTALPAWQALQQHRDAMQDFSMREAFAADSKRFDEFSLSCCGLFLDYSKNLINEQSRDLLVQLAEQVGLQDAIKSMFSGEIINASEGRPVLHTALRRPVGDKLSVNGVNVMPEVHKVLNQITELVGRIHDGLWRGYSEKPITDVVNIGIGGSFLGPELVSEALLPYAQRGVRCHYLANIDGSEFHELSANLRAETTLFIVSSKSFNTLETLKNAMAARTWYLAQGGSEAELYRHFIAVSSNKAAAVAFGIREENIFPMWDWVGGRYSLWSAIGLPIALAIGTANFKELLSGAYTMDQHFQTAPFEKNMPVLLALLGVWYGNFWGARSHAILPYDHYLRNITKHLQQLDMESNGKSVLTDGTPVKTDTGPVIWGGVGCNGQHAYHQLLHQGTQLIPADFIVPVVSFNPVADHHQWLYANCLSQSQALMLGKTREEAEAELRQKGLNEADIEKLAPHKVIPGNRPSNTLVVERISPRRLGALVAMYEHKVFVQSVIWGINAFDQWGVELGKELGKGVYQRIVGSLEDSAEDGSTQGLINYFRGRHRG
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PECA1_BOVIN
Sequence: MQLRWTQRGMMWLGALLTLLLCSSLKGQENSFTINSIHMQILPHSTVQNGENLTLQCLVDVSTTSRVKPLHQVLFYKDDVLLHNVSSRRNTESYLIPHVRVCDSGRYKCNVILNNKEKTTPEYEVWVKGVSDPRVTLDKKEVIEGGVVVVNCSVPEEKAPVHFTIEKFELNIRGAKKKREKTSQNQNFVTLEFTVEEQDRTIRFQCQAKIFSGSNVESSRPIQSDLVTVRESFSNPKFHIIPEGKVMEGDDLQVKCTVQVTHQAQSFPEIIIQKDREIVAHNSLSSEAVYSVMATTEHNGNYTCKVEASRISKVSSVVVNVTELFSKPKLESSATHLDQGEDLNLLCSIPGAPPANFTIQKGGMTVSQTQNFTKRVSEWDSGLYTCVAGVGRVFKRSNTVQITVCEMLSKPSIFHDSRSEVIKGQTIEVSCQSVNGTAPIFYQLSNTSKPVANQSVGSNKPAIFRVKPTKDVEYCCSADNCHSHSKMFSEVLRVKVIAPVDEAQLVVLKGEVEPGEPIVFYCSVNEGSFPITYKFYKEKESKPFYQDTINATQIMWHKTTASKEYEGQYYCTASNRANLSKHVIQSNTLTVRVYLPLEKGLIAVVVIGVIIVTLVLGAKCYFLKKAKAKQMPVEMSRPAVPLLNSNNEKTLSDAGTEADRHYGYNEDVGNHAMKPLNENKEPLTLDVEYTEVEVTSPEPHQGLGTKGTETETVYSEIRKADPDFVENRYSRTEGSLDGS
What is the function of this protein?
Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions.  Tyr-689 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes.  Trans-homophilic interaction may play a role in endothelial cell-cell adhesion via cell junctions.  Heterophilic interaction with CD177 plays a role in transendothelial migration of neutrophils.  Homophilic ligation of PECAM1 prevents macrophage-mediated phagocytosis of neighboring viable leukocytes by transmitting a detachment signal.  Promotes macrophage-mediated phagocytosis of apoptotic leukocytes by tethering them to the phagocytic cells; PECAM1-mediated detachment signal appears to be disabled in apoptotic leukocytes.  Modulates bradykinin receptor BDKRB2 activation.  Regulates bradykinin- and hyperosmotic shock-induced ERK1/2 activation in endothelial cells.  Induces susceptibility to atherosclerosis.
What are the official names of this protein?
Platelet endothelial cell adhesion molecule, PECAM-1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Membrane raft. Cell junction. Note=Localizes to the lateral border recycling compartment (LBRC) and recycles from the LBRC to the junction in resting endothelial cells. Cell surface expression on neutrophils is down-regulated upon fMLP or CXCL8/IL8-mediated stimulation.
Protein: TMPPE_HUMAN
Sequence: MAIFRQLSLGAKATLAAVTVFVSMIASRSYLAESLELRAWRWLLRLQLALFVNSLLLIGSLYIWRSTVSNLCHSPAAESTCFQLWKVVVLAFLALAHSSFFTMFFLVAEEPYLFSLAAYSCLGAYIIMLFFLFILSGMEQAYQLLAWRSGRVVGSLEKTRKLVLRPALAVGVTAVLSVAGILNAAQPPAVKTVEVPIHQLPASMNNLKIVLLSDIHLGPTVGRTKMEMFVRMVNVLEPDITVIVGDLSDSEASVLRTAVAPLGQLHSHLGAYFVTGNHEYYTSDVSNWFALLESLHVQPLHNENVKISATRAQRGGGGSGSGSEDEDWICLAGVDDIEADILHYSGHGMDLDKALEGCSPDHTIILLAHQPLAAKRALQARPDINLILSGHTHAGQIFPLNVAAYLLNPFFAGLYQVAQATFVYVSPGTAYYGIPMRLGSRAEITELILQRSP
What are the official names of this protein?
Transmembrane protein with metallophosphoesterase domain.
What is the protein family that this protein belongs to?
Belongs to the metallophosphoesterase superfamily. LOC643853 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: VE2_HPV25
Sequence: MENLSERFNVLQDQLMNIYETAAQTLEAQIEHWQILRREAVLLYFARQKGVTRLGYQPVPALMVSEAKAKEAIGMVLQLQSLQKSEFGKEPWSLVDTSTETYKSPPENHFKKGPMPIEVIYDKDADNANAYTMWRYIYYVDDDDKWHKSASGVNHTGIYFMHGSFRHYYVLFADDARRYSNTGHWEVKVNKDTVFTPVTSSTPPESPGGQADSNTSSKTPTTDTASRLSPTGSGERSQQTSTKGRRYERRPSSRTRRQQAQARQRRSRSKSRSRSRSQSRSRIRSRSRSRSRSESQSSKRRSRSRSRRKTSATRGRGPGSPTTTTSDRAARSPSTTSSATSQRSQRSRSRAGSSRGGRGRGGRRRHRLSESPTSKRSRRESGSVRLHGVSADAVGTSVHTVSSRHTGRLGRLLEEALDPPVILVRGDANTLRSFRNRAKHMYTGLFSSFSTAWSWVAGDGIERLGRSRMLISFISNSQRKHFDDAVRYPKGVDRSFGSFDSL
What is the function of this protein?
Plays a role in the initiation of viral DNA replication.  A dimer of E2 interacts with a dimer of E1 in order to improve specificity of E1 DNA binding activity.  Once the complex recognizes and binds DNA at specific sites, the E2 dimer is removed from DNA.  E2 also regulates viral transcription through binding to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory regions of the viral genome.  Activates or represses transcription depending on E2RE's position with regards to proximal promoter elements including the TATA-box.  Repression occurs by sterically hindering the assembly of the transcription initiation complex.
What are the official names of this protein?
Regulatory protein E2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E2 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: ATPH_ORYSJ
Sequence: MNPLIAAASVIAAGLAVGLASIGPGVGQGTAAGQAVEGIARQPEAEGKIRGTLLLSLAFMEALTIYGLVVALALLFANPFV
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, chloroplastic, ATP synthase F(0) sector subunit c, ATPase subunit III, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: AROB_YERPA
Sequence: MEKITVTLGERSYPITIAAGLFNDPASFKPLKAGDQVMLVTNQTLAPLYLDSLRAVLEHGGIKVDQVILPDGEQYKSLSVMEQVFSALLEKPHGRDTTLVALGGGVVGDLTGFAAACYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVVDLNCLKTLPPRELASGLAEVIKYGIILDAAFFDWLENNIDALLALDMSALAYCIRRCCELKADVVAADEREESGARALLNLGHTYGHAIEAEMGYGVWLHGEAVAAGMVMAAQTSRRLGQLSVSDVERIKKLLLRAGLPVCGPKEMAPESYLPHMMRDKKVLAGELRLVLPTAIGKSEIRGGVAHDMVLASIADCRP
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_BORRA
Sequence: MINKIYGKIVDKKESSIIILAFPFEFEILVSSFCKMELRLLEDVEILTYFHFRDDDVKLFGFLNISEREVFENLIGVDGIGPKAALKILSGIKYDAFRLAIAKEDINLISKVKGIGNKIAGKIFLKLRGKLVKGDESSSYMLKFKELEQSIVNMGFDRKLVVVAFREIMLSDKFLILKEAEQEQFLFTETLKRLSV
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: SCRB_VIBC3
Sequence: MLLDTLLELAGGINNVTRILAPQGQVVLALKHPPHAPHLPDDVSLQSVLGEWQLSVQRTAEVSDQQLAAIGKAIAERQKRATLPYQTALDCPYRPQWHISPPQGLLNDPNGFIYHQEEYHLFYQWHPFACEHKDKYWVHLKSLDLVHWQWQSVALTPSDWFDSHGVFSGHAVSHQQDLWLFYTGNTRLGTERQRQTMQCAARMNANGEFEKLGPVIRCLPEGVTEHIRDPKVIYTQGKWQMLLGAQTLAHQGRLAVYHSDDLLHWHFDKLYGDELGDYGYMWECPDWFELQGEAFFVFGPQGIASANPHHTIEHQNRIFRATQNAQGEIALLQGWPLDEGFDFYAPQTAQTADGRRVLCGWMGLPDETQHPSCDQGWIHQLTALRELEWREGKIYQHPLRELDTLQSEPHTLLLSDTVTELKTKSFDLQVTLPWGCELRLMQNAQYCVTLTLDAENRLLRLDRSATQIRQGDTIRELKLDSPTVELRILADQSSLEIFINQGEHVMTSRIFTPLDATGISLHGASVDAKLYYMAPASAPFNLEVNV
What is the function of this protein?
Enables the bacterium to metabolize sucrose as a sole carbon source.
What are the official names of this protein?
Probable sucrose-6-phosphate hydrolase, Sucrase, Invertase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 32 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_PHYMT
Sequence: MAKLTKKNFIDSLREMSLLEVKELVDGLKEEFGIDPNALFVSGSNQDNNKIQVEEKTEFSVIVKDFGDSSNKIPIIKTVKEITGFGLYDIQKLLNTPDAVIQEKISKEKAEEIKNKLELIGAVVEIQ
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: ICP27_HCMVM
Sequence: MELHSRGRHDAPSLSSLSERERRARRARRFCLDYEPVPRKFRRERSPTSPSTRNGAAASEYHLAEDTVGAASHHHRPCVPARRPRYSKDDDTEGDPDHYPPPLPPSSRHALGGTGGHIIMGTAGFRGGHRASSSFKRRVAASASVPLNPHYGKSYDNDDGEPHHHGGDSTHLRRRVPSCPTTFGSSHPSSANNHHGSSAGPQQQQMLALIDDELDAMDEDELQQLSRLIEKKKRARLQRGAASSGTSPSSTSPVYDLQRYTAESLRLAPYPADLKVPTAFPQDHQPRGRILLSHDELMHTDYLLHIRQQFDWLEEPLLRKLVVEKIFAVYNAPNLHTLLAIIDETLSYMKYHHLHGLPVNPHDPYLETVGGMRQLLFNKLNNLDLGCILDHQDGWGDHCSTLKRLVKKPGQMSAWLRDDVCDLQKRPPETFSQPMHRAMAYVCSFSRVAVSLRRRALQVTGTPQFFDQFDTNNAMGTYRCGAVSDLILGALQCHECQNEMCELRIQRALAPYRFMIAYCPFDEQSLLDLTVFAGTTTTTASNHATAGGQQRGGDQIHPTDEQCASMESRTDPATLTAYDKKDREGSHRHPSPMIAAAAPPAQPPSQPQQHYSEGELEEDEDSDDASSQDLVRATDRHGDTVVYKTTAVPPSPPAPLAGVRSHRGELNLMTPSPSHGGSPPQVPHKQPIIPVQSANGNHSTTATQQQQPPPPPPVPQEDDSVVMRCQTPDYEDMLCYSDDMDD
What is the function of this protein?
Immediate early (EI) protein that plays many roles during productive infection including regulation of host cell cycle progression, regulation of viral gene expression or nuclear export of intronless viral RNAs.  Acts as a transcriptional transactivator via interaction with the cellular transcription elongation factor SUPT6H and as a nuclear RNA export factor via interaction with UAP56, a component of the cellular mRNA export machinery (By similarity).
What are the official names of this protein?
mRNA export factor ICP27 homolog.
What is the protein family that this protein belongs to?
Belongs to the HHV-1 ICP27 protein family.
What are the subcellular locations of this protein?
Virion tegument. Virion. Host nucleus. Host cytoplasm. Note=Shuttles between host nucleus and cytoplasm.