PharMolix/UniProtQA huggingface dataset:
Protein: CE63B_XENLA
Sequence: MEALLQGLQRQDRMGALQDSCEAELQELMKQIDIMLDHKRSQWEAETETMKTRLELKEQELNCALDSEERLNQEVRRLRQQLIQQEEETQNKTTQYEAQLSGFKEELNRLKKSYEKVQKKHLRSEMKAKAEEERSEVSRLTRRLEEFRQRSLDWEKQRLLYQQQLSGLEAQRKTLIEQTEMYQQQSHNRKQMLEQTNLVGRSELQNLSGQLHRANDSLCAKEEELETLKIQLRCAVEGQKRAEHETELSKQAVQALKEKAELRATLQAHTEFLQGSRVQKHELLPEGYRGSEVLRENNSIRSLEERLQETGQVGGETEVEAIRSKLSVSRMNEQRLQAEVTCLEDSVESVTSQCQLLAKELKGKEEYLHGVKEDHQKCLSENKKLKGQLSQAELTHKSVLDGMRKEISQLTQELHQRDIRMASSAGIDWERKIKAERQRAEREAAEHRMSLNALENLRQENCRLSELLQTQEPDVAQALVNLEQANQRLQRELLQTQEKLELIAQRRESEIQNAVDSISQELLNKQEQELRIMQERLKVYEQEMQTFRSQQDAASSGSSLESIFSEVWKEQATGSPISAASVDSAIEPVEDLASSLPVPPTSPANAVASRFLQEEEQRSHELLQRLNAHIEELKQESQRTVEHFTQAR
What is the function of this protein?
Required for normal spindle assembly.  Plays a key role in mother-centriole-dependent centriole duplication.  Plays a role in DNA damage response.  Following DNA damage, such as double-strand breaks (DSBs), is removed from centrosomes; this leads to the inactivation of spindle assembly and delay in mitotic progression.
What are the official names of this protein?
Centrosomal protein of 63 kDa-B, Cep63-B.
What is the protein family that this protein belongs to?
Belongs to the CEP63 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole.
Protein: SYW_STRP8
Sequence: MTKPIILTGDRPTGKLHLGHYVGSLKNRVFLQNENKYKMFVFLADQQALTDHAKESELIQESIGNVALDYLSVGLDPKQSTIFIQSQIPELAELSMYYMNLVSLARLERNPTVKTEIAQKGFGESIPSGFLVYPVSQAADITAFKANLVPVGNDQKPMIEQTREIVRSFNHTYHTDCLVEPEGIYPENEKAGRLPGLDGNAKMSKSLGNGIYLSDDADTVRKKVMSMYTDPNHIKIEDPGQIEGNMVFHYLDIFARKEDQADIEAMKEHYQRGGLGDVKTKRYLLDILERELAPIRERRLEYAKDMGEVFRMLQEGSQKARTVAAKTLSEVKSAMGINYF
What is the function of this protein?
Catalyzes the attachment of tryptophan to tRNA(Trp).
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_MANSM
Sequence: MATNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTMMKLDPYINVDPGTMSPTQHGEVFVTQDGAETDLDLGHYERFIRTKMTKRNNFTTGKIYSEVLRKERRGDYLGATVQVIPHITNEIKARVIEGAAGHDVAIVEVGGTVGDIESLPFLEALRQLAVQVGREKTIFMHLTLVPYIPTAGEVKTKPTQHSVKELLSIGIQPDVLICRSDRMVPPNERAKIALFCNVPEKAVISLKDVDSIYRIPALLQSQGLDDLICQRFRLACKEADLSEWEQVLYRQANPTGDVTIGMVGKYVELPDAYKSVNEALKHAGLTNRLNVHIKYIDSQDVETKGIDVLKGVDGILVPGGFGYRGVEGKILTAQYARENNIPYLGICLGMQVAFIEYARHVAGLTQANSSEFDKNCPQPVVGLITEWQDADGSVEQRSENSDLGGTMRLGAQQCHLIEGSKARELYGKETIEERHRHRYEVNNTLLPQIEAAGLKVTGLSADKKLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAAKENQKK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: GLNE_MANSM
Sequence: MTMPLPSIEQTLIQLADNLITHFPEQFNSQIYQQIQKDISNIKTPVGALMRAVSMSDFVTEILQKQPHFLAECWHKTPQLADCDSYAARLSVQLADIREETGLYKTLRDFRNQEMAKLSICQSLNSATVEEIFIRLSQLAEALIIGARDWLYQRACLDWGTPTDNQGNVQQLYILGMGKLGGFELNFSSDIDLIFTYPANGETVGSRKPIDNQKFFTRLGQRLISALDEFTEDGFVYRTDMRLRPFGDSGALALSFNAMESYYQEQGRDWERYAMIKGRILGADEQDPNVKTLRQLLRPFIYRRYIDFSVIQSLRDMKSKIEREVLRRGLVDNIKLGAGGIREIEFIVQVFQLIRGGREISLQQHELLKLLPEIEKLNLITADQHQDLLQAYLFLRRVENVLQAINDKQTQLLPADELNRCRLISATCEFTQWDNNHRPQKIQYPIHDWESFYQVLQQHQQKVRSVFNNLIGFNNENEADDSDNAWSDFLDADLEQGEIADILAQQGVSEEERDEIIGRLEAFRHSVSHRSIGIRGREVLTQLMPLLLLQIFSNKKYRTLLPRMLNIVEKILTRTTYLELLLENPQALTQLIELCAKSQLIAEQVAQHPILLDELLDREALLNPPSFEQYPAELQQYLLRLPEDDDEQFITALRQFKQATLLRIAAADILGALPVMKVSDHLTFLAETILHTVVNLAWQQITARFGKPEHLQNNEKGFLVAGYGKLGGIELGYRSDLDLVFLCDEIHSGQTVGGKKVIDSHQFYLRLAQKIISIFSMTTSAGILYEVDLRLRPSGEAGPLCCSFKAFEDYQMNEAWTWEKQSLVRSRAVYGEPALREKFELIRTGILASPRDLTQLKIDVREMREKMYRHFAGADDNKFNIKKDQGGITDIEFIAQYLVLAHAPENPNLAYWSDNVRIFDIMAEHGIITLNEAEKLKNCYTGLRNQIHHLNLLGEPPIVSKEEFADERRFIHQIWQKLFFE
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia.  When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity.  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity.  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.
Protein: Y1464_PARXL
Sequence: MLRYAAIFFIIAIIAAVFGFGGIAAGATEIAKVLFFIFVVIFLVTLLMGVMRR
What are the official names of this protein?
UPF0391 membrane protein Bxeno_A1464.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PRMA_BRUSI
Sequence: MAQSRLFFSADKAEAERTYNILEQAFEDDGFPIAITEIDEDRQIFEVSVYVEDDAEEVAARVDALVGPGLFDTEELPDIDWVTHSLEGLKPVRAGHFFVHGSHDRDKIEPGDIAIEIDAGLAFGTGHHGTTAGCLELIEETVQTEHPTNALDLGTGSAVLAIAIARLAPIPILATDIDPIAVTVAAENAAKNGVAEHIVTATAEGFGHPIFRSYSPFDLIVANILANPLIELAPSIKEHLAPGGSIILSGILDSQHDAVLAAYQTQGLTHQKTLHREGWVAIHLK
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACSF2_THEVB
Sequence: MVAIAPNPHSGQSVKTIRENLLTPRFYTTDFEQAAKLDLSRQQEQLEAMLAEMRADYNRHHFVRDDSFKGTWDLLDAQTRKAFIDYLERSCVSEFSGFLLFKELSRKLKDRNPLLAEIFHLMARDEARHAGFLNKAMMDFGHAMDLGYLSKTRTYTFFPLPWVLYTVYLSEKIGYWRYIIIYRHLEKHPEHSFYPLFNYFERWCQDENRHGDIFKALIHSQPQLIQGWGAKLWMRFFLLTVFATHTLTVHERAKFYEALGLDATAFDREVIAKTNETAARTFSVVLNVDHPEFYSRLQRCVEISNKLQAIEATHQPKWLKALRKLPHQLAIAGHLLRIYLLPPVNAQQEWGTVH
What is the function of this protein?
Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis.  Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME).
What are the official names of this protein?
Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase 2, Mg-protoporphyrin IX monomethyl ester oxidative cyclase 2.
What is the protein family that this protein belongs to?
Belongs to the AcsF family.
Protein: IF5A1_NICPL
Sequence: MSDEEHHFESKADAGASKTYPQQAGTIRKNGHIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFTGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDGFVSLLTENGNTKDDLRLPTDDNLLALIKDGFAEGKDLVLSVMSAMGEEQICGIKDVGPK
What is the function of this protein?
The precise role of eIF-5A in protein biosynthesis is not known but it functions by promoting the formation of the first peptide bond.
What are the official names of this protein?
Eukaryotic translation initiation factor 5A-1, eIF-5A-1, eIF-4D.
What is the protein family that this protein belongs to?
Belongs to the eIF-5A family.
Protein: AFG32_BOVIN
Sequence: MAHRCLLLWGRGACRPRGMPPMLLPGGRTGSTERLYLRMLYRYATTQAKTSRNSLLTDVIAAYQRLCSRPPKGFEKYFPNGKNGKKTSEPKEVMGEKKEPKPAAAPRPSGGGVGGGGKRGGKKDDSHWWSRFQKGDIPWDDKEFKMYFLWTALFWGGFLFYFLFKSSGREITWKDFANNYLSKGVVDRLEVVNKRFVRVTFTPGKTPVDGQYVWFNIGSVDTFERNLETLQQELGIEGENRVPVVYIAESDGSFLLSMLPTVLIIAFLLYTIRRGPAGIGRTGRGMGGLFSVGETTAKVLKDEIDVKFKDVAGCEEAKLEIMEFVNFLKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATAGEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRGNFGGQSEQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALMRPGRFDRQIFIGPPDIKGRASIFKVHLRPLKLDSTLEKEKLARKLASLTPGFSGADVANVCNEAALIAARHLSDSINQKHFEQAIERVIGGLEKKTQVLQPEEKKTVAYHEAGHAVAGWYLEHADPLLKVSIIPRGKGLGYAQYLPREQYLYTREQLLDRMCMTLGGRVSEEIFFGRITTGAQDDLRKVTQSAYAQIVQFGMNEKVGQISFDLPRQGDMVLEKPYSEATARLIDDEVRILINDAYKRTVALLTEKKADVEKVALLLLEKEVLDKNDMVELLGPRPFAEKSTYEEFVEGTGSLDEDTSLPEGLKDWNREREGSEEPSGEKVTSPVQGAGPA
What is the function of this protein?
ATP-dependent protease which is essential for axonal and neuron development.  In neurons, mediates degradation of SMDT1/EMRE before its assembly with the uniporter complex, limiting the availability of SMDT1/EMRE for MCU assembly and promoting efficient assembly of gatekeeper subunits with MCU.  Required for the maturation of paraplegin (SPG7) after its cleavage by mitochondrial-processing peptidase (MPP), converting it into a proteolytically active mature form.  Required for the maturation of PINK1 into its 52kDa mature form after its cleavage by mitochondrial-processing peptidase (MPP) (By similarity).  Involved in the regulation of OMA1-dependent processing of OPA1 (By similarity).  Contributes to the proteolytic degradation of GHITM upon hyperpolarization of mitochondria (By similarity).  Progressive GHITM degradation upon persistent hyperpolarization leads to respiratory complex I degradation and broad reshaping of the mitochondrial proteome by AFG3L2 (By similarity).
What are the official names of this protein?
AFG3-like protein 2.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RSMA_NITHX
Sequence: MSTIDDLPPLRDVIKRHALSARKSLGQNFLLDLNLTARIARAAGPLEDATVIEIGPGPGGLTRALLAMGAQRVIAIERDARALGALEEISGRYPGRLTIVNADATQFDSRPLLGTTRAKIVANLPYNIATALLIDWLSVEPWPPWYDTMVLMFQREVAERIVARENEEAYGRLAVLSNWRAETKILFDISPAAFVPQPKITSSVVRLVPRDKPETCERRLLEQVAAAAFGQRRKMLRQSLKSLPADPARLTAAAGIEPTQRAETVPISGFAAMARELADIRNRTNRA
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_BURMA
Sequence: MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGSVYVIADRNINTLIDYRYAKKHMARNGENGRGSDCYGKGGDDITLRMPVGTVINDMDTGELIADLTEHDQKVLVAKGGAGGLGNLHFKSSTNRAPRQKTDGKPGERRMLKLELKVLADVGLLGMPNAGKSTFISSVSNAKPKIADYPFTTLAPNLGVVRVGPGKSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGLLLHLVDLAPFDERVDPVAEARAIVGELRKYDESLYEKPRWLVLNKLDMVPEDERRARVADFIERFGWTGPVFEISALTGQGCEGLVYAIHDYLVEHSDAHRAELAEDLASDVRFRDAPGAGGEPHERDAGAH
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR5_SYMTH
Sequence: MTEKGLTYADAGVNRERHYELVRRIAAHTARTLRRPGTLGNIGAFGGLFQLDPARYPEPVLVSGTDGVGTKLRLAFLSGRHDTVGIDLVAMSVNDILCQGAEPLFFLDYIGIGQKDLAVLEQVVKGIADGCLQAGCALIGGETAELPGMYPPGEYDLAGFAVGIVNRDRLLTGEKVAPGDALVGLASSGLHANGYSLARRVLLKVDGGAFDLDDRPPELGGRTVLEVMLTPTRIYVRTVLRLLARFDVHGIANITGGGLHENIPRMLPEGTAAVLRRGAWKEPPVFDLIRRLGPVAQAEMEATFNLGLGMVLAVPADQAEAVAAAARELGEEAWVVGEVAAAEPGGPRVVVRR
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_EIMTE
Sequence: MAFVKAIKNKAYFKRFQVKYRRRREGKTDYAARRRLILQDKNKYNAPKYRFVVRVTNSRVLCQVMYATLQGDRLVCSADSQELTRYGIKVGLTNYSAAYATGLLLARRLLKQKGLADEFKGLEKPSGEEYHIEEVSEERRPFKCVLDVGIVATTVGNRVFGAMKGACDGGLHIPHSNKRFPGFTKGEDGADDSYNPEVHRARIYGLHVAEYMRTLKEEDPERYQAQFSAYIRNKIDPDSIEKMYEEAFQKIRANPDPVKKEAREVKRVRQGAMIKTAKSQYVRNVKLDKETRKERVLKKIQMVADKMAEEE
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y491_GEOTN
Sequence: MGIKYSSKINKIRTFALSLIFVGVIVMYLGLFFRTSPIIMTLFMVLGLLFLVASGIVYFWIGTLSTRAVQVVCPSCGKVTKMLGRVDLCMFCREPLTLDRELEGKEFDEKYNKKRKN
What are the official names of this protein?
UPF0295 protein GTNG_0491.
What is the protein family that this protein belongs to?
Belongs to the UPF0295 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ENOB_RABIT
Sequence: MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKSRYLGKGVLKAVEHINKTLGPALLEKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGNHDLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFREAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKVVIGMDVAASEFHRNGKYDLDFKSPDDPARHITGQKLGELYKSFIKNYPVVSIEDPFDQDDWATWTSFLSGVDIQIVGDDLTVTNPKRIAQAVEKKACNCLLLKVNQIGSVTESIQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEALGDKAVFAGRKFRNPKAK
What is the function of this protein?
Glycolytic enzyme that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate.  Appears to have a function in striated muscle development and regeneration.
What are the official names of this protein?
Beta-enolase, 2-phospho-D-glycerate hydro-lyase, Enolase 3, Muscle-specific enolase, MSE, Skeletal muscle enolase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localized to the Z line (By similarity). Some colocalization with CKM at M-band.
Protein: CMOA_YERPN
Sequence: MPNRDTQSQNDTPRHSPEAAEPQRDSLFAAPIAKLGDWTFDEKVAEVFPDMIQRSVPGYSNIISMIGMLAERFVQPNSQIYDLGCSLGAATLSMRRNIKAEGCKIIAVDNSPAMVERCRRHIDAFRAETPVDVVEADILDIKLENASMVVLNFTLQFLEPANRQRLLNQVYQGLRPGGALVLSEKFSFADHNVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVETHKNRLHQAGFEHAEVWFQCFNFGSLIALKAGEAQ
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: LOT5_KLULA
Sequence: MVVHPNEKQFCQLILTKPTVENVATIGQYQLTQPRLKGINLLEQSDLPILYGGGRDFMFGELNSELEQAEHATTNSPPQMILSDLFVLNTCVLIWFQDWERSLQIPYRNIMYHAIRKIDDRHLTEGHRLELMIAIERDPIINELFPLPNVSKANNFTGTGSYLQETTLSSVELILRPKYANFDRHYNVEVEDLFTFKEFGLNRGDTMVKNCHNAILTCMDFYPEEEPTNQQCTQPHSTTTEISAMPDIGHLQNVYVNSGTADDLDGDSTMDIYAQDGFDASMALQFYADQPLAGQKHRV
What are the official names of this protein?
Protein LOT5.
What is the protein family that this protein belongs to?
Belongs to the LOT5 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SYT_DESAL
Sequence: MINITLPDGKIVESDGPVSGEDVAKGISEGFARNCVAVEVDGKLTDLSTPIETDASVVFITTKDEQGLDIMRHSAAHVMAEAILNLYPDAKLTIGPVIEDGFYYDIDMPPISEDDFPKIEQEINKIIKAKKPFVRKTLSKAEALDFYKDNAFKTELISELEDGTISIYEQGGFTDLCRGPHVPNTGLVKTLKLMKVSGAYWRGDSERPMLQRLYGTAFFDKKELKSYLHLLEEAKKRDHRKLGTALDLFSFHEEAAGMPFFHARGMELWNALLAYWREEHKKAGYVETKTPIMLNKSLWERSGHWENYRENMYTSLIEDFDYAIKPMNCPGGMLLYKTKHHSYNDLPIRAGEIGLVHRHELSGVLSGLFRVRAFHQDDAHIFMTEEMIEDEILGVLQLVERMYSTFGLGFHLELSTRPEKTIGTDEQWEKATEGLRAALDKSGRDYKINEGDGAFYGPKIDIHIKDALGRTWQCGTIQLDMNLPERFDLTYVGADNQRHRPVMIHRVIYGSIERFLGILIEHYAGKFPLWLSPCQAVVLAMNDDVAGYAKEVKARLEEAGLRMEIDLRAESINKKVRDAQLSKIPLMLTVGGKEEAAQTLAVRTLDGKVKYGVTIDNFLDKVLPHIETRNPDLVEF
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACL4_YEAST
Sequence: MSELEATIRQAKEALAENNAKKALKILKPFKSSLKKENANNVILNEVFADAYLDNGQVEKAYPILARACELDPEGQVGGPDKFFTMGQIMGGQDGVSIITRGIMNISNTGGEMLTNVQVEKIVGGLLSVIEIWMTDLCMEPNAEEQCEELIQKAMELTEGKSPETWSTLGSIKISQQKFGEAYEAFSQAWNFFELKKQEIGSGINENGDTTQKAGLQSEYVDLLQPLLSLTKMCLEVGAYEVALKVIAAVRDIDEDNIEGYYLEGFTYYLMSKLEIFKLNNPEVSLRPENIYEFNQLIQEVPLDLSHEPISQLIYDSRLALSFALQAGVNADSKDEIVQELLGGANALLQEIGGPLDPSELTQIKKGDLVNENEDLEELDIEEEYSD
What is the function of this protein?
Acts as a chaperone for the L4 ribosomal subunit encoded by RPL4A and PRPL4B, required for hierarchical ribosome assembly.  Shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.
What are the official names of this protein?
Assembly chaperone of RPL4.
What is the protein family that this protein belongs to?
Belongs to the ACL4 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Distributed throughout the cell but is enriched in the nucleus.
Protein: COXX_RHIL3
Sequence: MTVIDNHGVLAKDGELSEASARDYFELLKPRVMSLVVFTAFAGLVLAPGHIHPVLGTIAILCIAVGAGASGALNMWYDADIDAIMSRTANRPIPAGRIAPSEALAFGLVLSGFSVVILGLAVNWLSAGILAFTIFFYAVVYTMWLKRSTPQNIVIGGAAGAFPPMIGWACVTNSVTIESTVLFLIIFLWTPAHFWALALFKMRDYEAVGVPMLPNVAGERVTKHQIVAYAVLTAVCAVLPSFLGFASLGYGLVAAALGAIFIYCSIAVWRMPDGDLKMIPAKKLFGFSIFYLFAVFSALMIDRLAPVLVSHAGGWF
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYIC_ENCCU
Sequence: MYRKNANFVECEEEVLEYWRRNKSFERSCERSRGREKFTFYDGPPFATGLPHYGHLLSGTIKDTVTRFFYQQGYDVDRRFGWDCHGLPVEYEIDKKLGISSRAEVLEMGIGKYNAECRGIVMKYSSEWEAVVERLGRWVSFRDGYRTMDMTFMESVWNIFKELFSRGLIYRGFRVMPFSTACSTPLSNFESNQNYKDVSDPSVLIAFPLLKPLGGYMLSLVAWTTTPWTLPSNCGLAVNPGFLYGVFEHKEKFYLMHVDRIGEYFKDARILQRVSGRELEGLEYEQPFDYFEEYRKKGFFRVLASGFVTDTDGTGVVHCAPGFGECDYNAFVEKGLIRENDLVPCPVDENGRYTSEVRRYAGRYVKDCDKAILSDIRDKVLMNQRIVHKYPFCWRSDTPLLYKLVPNWFVKVKDHVDSLLRNNEKINWVPPDIKYKRFHNWLENARDWSISRNRFWGTPIPLWVTEDYSDMICIGSVGELEELSGRKIDDIHREFIDGIVIHRNGREYRRVEEVLDCWFESGSMPYAQDHWPFCKESGVDLGSLSVSGGEERNKKLVKENFPAHFIGEGLDQTRGWFYTLHVISSLLFGQPAFLNVVVNGIVLAEDGRKMSKRLRNYPDPSHIFNTYGADSLRMYLISSPVVEAENLKFSEGGVKEVLKTLIIPWYNSLGFYLENRDVEPDGRSLPMDGWITASFDNFAWSLTRKMRKYELSSVLTLALRFIDDLSNWYIRMYRKEIRAGHHAVLGEILKKFSIVMGPFTPFFSEYSYQSLNPGESVHFQEYPVCKNGTHPFEMAKSIIAAVRRLRETNSISLKTPLKSATLMSSSSLYEGIKDYIDAIKTECNVLELLYKEEDRSMFDITVKPNFLSLKKDKATMKKKMKVIQGLTGDQAYSLLSSPLVVDGLEILRDDVLIVKKIRCEGIAQEFGDFSIIIDNTLDEGMVKMKIAREFHSYIQKLRKSAGLRVGDDVVVDIQCPDLKGIVSKYFDISFGSLGALSGRGEYEFDGTLYPVSLYKKL
What are the official names of this protein?
Probable isoleucine--tRNA ligase, cytoplasmic, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPA12_PANTR
Sequence: MSVMDLANTCSSFQSDLDFCSDCGSVLPLPGAQDTVTCIRCGFNINVRDFEGKVVKTSVVFHQLGTAMPMSVEEGPECQGPVVDRRCPRCGHEGMAYHTRQMRSADEGQTVFYTCTNCKFQEKEDS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Component of RNA polymerase I which synthesizes ribosomal RNA precursors.
What are the official names of this protein?
DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit H.
What is the protein family that this protein belongs to?
Belongs to the archaeal RpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
Protein: Y1721_STAA8
Sequence: MENFDKTMKFDYEELPTQDVRDVLNNVYRTLDERGYNAVNQIVGYLLSGDPAYIPRQNEARNQIRHIDRDVIMEELVSYYLKEQNK
What are the official names of this protein?
UPF0297 protein SAOUHSC_01721.
What is the protein family that this protein belongs to?
Belongs to the UPF0297 family.
Protein: NUOH_CAMJJ
Sequence: MSDFAFFALETLIKCIIIIAIFASLAGLATYAERKVLAYFQRRIGPDMVGPFGLIQLVADMIKLFTKEDIIPSNSQKFIFAIAPLISAICAFVSLAAIPMLPEFTLFGRVIQPIVADINVALLFVIGTSGLCFYAVFLGGLASNNKWSILGAARGLVSIISYESVGALALIAIIMLVGSFSLVDINNYQSDGFFSWLIFKQPLAFVLFIIALFIETNRTPLCLTENDAEIVAGYGTEYSGLRWGIFFIGEYTSMIAGAILVTLLFLGGFNSFWIIPGWIMMIVKSSFIFFWYFWARAAFPQLRPDQVMKMCYLILIPLAVLNLLITALTVLL
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.