PharMolix/UniProtQA huggingface dataset:
Protein: KCY_THEVO
Sequence: MRITIAGKIGSGKSTVSQEISKITGYSVYSSGTFFRESAKKMGMSIEDFNRYAETHPEADYATDGMQKDFMETHDNIIVEGRLAGWICKIYSISAFKVFLYATRYTRLVRFSNREGIEIDEAAKLLDEREISEKKRYLDLYGIDIDDLSIYDIVVNTEFMKPEEVAVLVLNRIDEMSRKEVYTPRILKGM
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XKS1_ASPTN
Sequence: MAISAAQNPLYIGFDLSTQQLKGLVVNSDLKVVYLSKFDFDADSRGFPIKKGVITNEAEHEVYAPVAMWLQALDTVLDGLRQQGLDFSRVKGISGAGQQHGSVYWGDRAEDLLQNLDPSKSLEAQLSDAFSHPYSPNWQDASTQKECDEFDAYLGSQEALAQATGSKAHHRFTGPQILRFQRKYPDVYRHTQRISLVSSFLASLFLGRFAPFDISDVCGMNLWNIKQGAYDEKLLKLCAGSFGVDDLKRKLGPVYEDGGLNLGSIHRYYVDRYGFNPDCTIIPATGDNPATILALPLRPSDAMVSLGTSTTFLMSTPSYQPHPATHFFNHPTTAGLYMFMLCYKNGGLAREQIRDAVNDKLGSSDDVWANFDRTALQTPPLGQKADSDPMKMGLFFPRPEIVPNLRSGQWRFDYNPADGSLHETTAGWDQPLDEARAIIESQMLSLRLRSRGLTSSPGDGKPPQPRRVYLVGGGSKNKAIAKIAGEILGGSEGVYKLEIGDNACALGAAYKAVWALERSNGQTFEDLIGQRWKEEDFIEKIADGYQPGVFEKYGQAVEGFEKMELQVLQQEKK
What is the function of this protein?
Highly specific D-xylulose kinase which participates in the catabolism of xylose.  Xylose is a major component of hemicelluloses such as xylan.  Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway (By similarity).
What are the official names of this protein?
Probable D-xylulose kinase A, Xylulokinase A.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y9182_DICDI
Sequence: MNKTVGPPTITPTGLSGGMNSTTGSSSTSNIYSSYYKAIDQFQNKNTTDKDLHETLKQGPISSNLFYNNFLNELNNKNNNFNNNNNNNNNNNSNSNNNNNNNSNIVYSNNMSNNYNNNYNNRFKK
What are the official names of this protein?
Putative uncharacterized protein DDB_G0277407.
Protein: CO3A1_MOUSE
Sequence: MMSFVQSGTWFLLTLLHPTLILAQQSNVDELGCSHLGQSYESRDVWKPEPCQICVCDSGSVLCDDIICDEEPLDCPNPEIPFGECCAICPQPSTPAPVLPDGHGPQGPKGDPGPPGIPGRNGDPGLPGQPGLPGPPGSPGICESCPTGGQNYSPQFDSYDVKSGVGGMGGYPGPAGPPGPPGPPGSSGHPGSPGSPGYQGPPGEPGQAGPAGPPGPPGALGPAGPAGKDGESGRPGRPGERGLPGPPGIKGPAGMPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGDNGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGSPGQRGEPGPQGHAGAQGPPGPPGNNGSPGGKGEMGPAGIPGAPGLIGARGPPGPAGTNGIPGTRGPSGEPGKNGAKGEPGARGERGEAGSPGIPGPKGEDGKDGSPGEPGANGLPGAAGERGPSGFRGPAGPNGIPGEKGPPGERGGPGPAGPRGVAGEPGRDGTPGGPGIRGMPGSPGGPGNDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGLPGPAGKNGETGPQGPPGPTGPAGDKGDSGPPGPQGLQGIPGTGGPPGENGKPGEPGPKGEVGAPGAPGGKGDSGAPGERGPPGTAGIPGARGGAGPPGPEGGKGPAGPPGPPGASGSPGLQGMPGERGGPGSPGPKGEKGEPGGAGADGVPGKDGPRGPAGPIGPPGPAGQPGDKGEGGSPGLPGIAGPRGGPGERGEHGPPGPAGFPGAPGQNGEPGAKGERGAPGEKGEGGPPGPAGPTGSSGPAGPPGPQGVKGERGSPGGPGTAGFPGGRGLPGPPGNNGNPGPPGPSGAPGKDGPPGPAGNSGSPGNPGIAGPKGDAGQPGEKGPPGAQGPPGSPGPLGIAGLTGARGLAGPPGMPGPRGSPGPQGIKGESGKPGASGHNGERGPPGPQGLPGQPGTAGEPGRDGNPGSDGQPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPSGKSGDRGETGPAGPSGAPGPAGARGAPGPQGPRGDKGETGERGSNGIKGHRGFPGNPGPPGSPGAAGHQGAIGSPGPAGPRGPVGPHGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGGAAAIAGVGGEKSGGFSPYYGDDPMDFKINTEEIMSSLKSVNGQIESLISPDGSRKNPARNCRDLKFCHPELKSGEYWVDPNQGCKMDAIKVFCNMETGETCINASPMTVPRKHWWTDSGAEKKHVWFGESMNGGFQFSYGPPDLPEDVVDVQLAFLRLLSSRASQNITYHCKNSIAYMDQASGNVKKSLKLMGSNEGEFKAEGNSKFTYTVLEDGCTKHTGEWSKTVFEYQTRKAMRLPIIDIAPYDIGGPDQEFGVDIGPVCFL
What is the function of this protein?
Collagen type III occurs in most soft connective tissues along with type I collagen.  Involved in regulation of cortical development.  Is the major ligand of ADGRG1 in the developing brain and binding to ADGRG1 inhibits neuronal migration and activates the RhoA pathway by coupling ADGRG1 to GNA13 and possibly GNA12.
What are the official names of this protein?
Collagen alpha-1(III) chain.
What is the protein family that this protein belongs to?
Belongs to the fibrillar collagen family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: TGT_ECO5E
Sequence: MKFELDTTDGRARRGRLVFDRGVVETPCFMPVGTYGTVKGMTPEEVEATGAQIILGNTFHLWLRPGQEIMKLHGDLHDFMQWKGPILTDSGGFQVFSLGDIRKITEQGVHFRNPINGDPIFLDPEKSMEIQYDLGSDIVMIFDECTPYPADWDYAKRSMEMSLRWAKRSRERFDSLGNKNALFGIIQGSVYEDLRDISVKGLVDIGFDGYAVGGLAVGEPKADMHRILEHVCPQIPADKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGHLFVTDGVVKIRNAKYKSDTGPLDPECDCYTCRNYSRAYLHHLDRCNEILGARLNTIHNLRYYQRLMAGLRKAIEEGKLESFVTDFYQRQGREVPPLNVD
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: DAPE_CAMJ8
Sequence: MNAKEFLIELLKFKSVTPNDDGALNFIAMELSDFEAFFIEKEGIKNLLLTKKFNDEGEHLAFGGHVDVVPAGEGWKNDPFEPLEEEGFIYARGAQDMKSGVAAFIDAVKDVSFKGRRLSLILTSDEEGEAKYGTKAVLEWMKEKNMLPDYAVVAEPTCVKKMGDSIKIGRRGSINGKLLIRGKQGHVAYPEKCINPVHDFAPVLKLLAGFDLDPGSAEFSPSKIVITDIRGGMGVCNVTPNDLKLMFNVRNSPDTSLEDVKSYVEKICHGLNYELELKQSSEAFLTNIDNKIVQKMNESVQKITHEVPELNTKGGTSDARYFAKYGVKVVEFGVCNDRIHAIDERVSIEEFEKLCLVFKDLIENF
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: PYRG_CROS8
Sequence: MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTRMTRRNNFTTGRIYSEVLRKERRGDYLGATVQVIPHITNAIKERILAGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEVGREHTMFMHLTLVPYMAAAGEVKTKPTQHSVKELLSIGIQPDVLICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIYEEANPVGEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVTVNIKLIDSQDVETRGEELLKGLDAILIPGGFGYRGVEGKIATARYARENNIPYLGICLGMQVAMIEYARNVAGMENANSTEFVPDCKYPVVALITEWRDENGNVETRSEKSDLGGTMRLGAQQCQLSDDSLVRKLYGEPVITERHRHRYEVNNMLLKPIEAAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEYQKRQAK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: RF1_YERP3
Sequence: MKSSIVAKLEALQERHEEVLAYLGDASVIADQDRFRALSREYAQLTDVTRCFKEWRSAQDDIEAAEMMLDDLEMREMAQEELKIAKARSEELEQQLQVLLLPKDPDDERDCFLEIRAGTGGDEAAIFAGDMFRMYSRYAETRRWKVEIMSASEGEHGGYKEIIAKISGDGVFGQLKFESGGHRVQRVPETESQGRIHTSACTVAVMPAIPEAELPEINAGDLRIDTFRSSGAGGQHVNTTDSAIRITHIPTGIVVECQDERSQHKNKAKAMSVLGARIRAAEMQKRQLAEASERRNLLGTGDRSDRNRTYNFPQGRVTDHRINLTLYRLDEVMEGKLDMLIQPIVQEYQADQLSALSEQD
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CFM9_ARATH
Sequence: MNQVFKGWSRGMSTSRGRSMRSKVESRMRKESGKTLREIRRAKKLKKKLMTDEERLIYNLKRAKKKVALLLQKLKKYDLPELPSPVHDPELFTSEQVQAFKKIGFKNKNYVPVGVRGVFGGVVQNMHMHWKFHETVQVCCDNFPKEKIKEMASMIARLSGGVVINIHNVKTIIMFRGRNYRQPKNLIPVNTLTKRKALFKARFEQALESQKLNIKKTEQQLRRMGVNPEDPVAMASIHRVASTFFNAIDKKEGTPYVFHGDKQSERGTSVDNREESEPGDEDSDQEELDRFIAEIEEAADKEWEEEEAAEQEESGRIRYWNREEFAGRSRTPELRSYGDASHGFRRNDRDTHSQRRPNDSDDDDDDGELDSEDDEIPKRFDRARSSNTNTRRPREDFKRRSPDPRPRPRAQVRSDDDVLSDLDNTMWDSEDEEDAPPANYISSSDDDEDENRTVSASSSKQSRFRNNSSRDGINNSKSKSGKQRDEDWDSD
What is the function of this protein?
Involved in the splicing of group II introns in mitochondria (PubMed:31359042).  Required for the splicing of mitochondrial introns found in nad1, nad2, nad4, nad5, nad7, rps3 and cox2 genes (PubMed:31359042).  Splicing of mitochondrial introns is crucial for mitochondrial biogenesis and function, plant growth and development, and plant response to abiotic stresses (PubMed:31359042).
What are the official names of this protein?
CRM-domain containing factor CFM9, mitochondrial, Protein CRM FAMILY MEMBER 9.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ADF1_CAEEL
Sequence: MSSGVMVDPDVQTSFQKLSEGRKEYRYIIFKIDENKVIVEAAVTQDQLGITGDDYDDSSKAAFDKFVEDVKSRTDNLTDCRYAVFDFKFTCSRVGAGTSKMDKIIFLQICPDGASIKKKMVYASSAAAIKTSLGTGKILQFQVSDESEMSHKELLNNCPDNAPVRRRMLYASSVRALKASLGLESLFQVQASEMSDLDEKSVKSDLMSNQRI
What is the function of this protein?
Depolymerizes growing actin filaments in muscle cells; required for the assembly of actin filaments into the functional contractile myofilament lattice of muscle (PubMed:8107682).  Competes with unc-87 for actin binding and inhibits the actin-bundling activity of unc-87 (PubMed:17684058).
What are the official names of this protein?
Actin-depolymerizing factor 1, isoforms a/b, Uncoordinated protein 60.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family.
Protein: CAPP_PSEPG
Sequence: MTDIDVRLREDVHVLGELLGETIRQQHGDAFLQKIEDIRHSAKADRRGPGEQLSSTLADLAEDDLLPVARAFNQFLNLANMAEQYQLIRRRDADQPEPFEARVLPELLARLKQAGHSNDALARQLAKLDIQLVLTAHPTEVARRTLIQKYDAIAGQLAAQDHRDLSPAERQQVRERLRRLIAEAWHTEEIRRTRPTPVDEAKWGFAVIEHSLWHAIPSHLRKVDKALLEATGLRLPLEAAPIRFASWMGGDRDGNPNVTAAVTREVLLLARWMAADLFLRDIDALAAELSMQQANDALRERVGDSAEPYRAVLKQLRDRLRATRAWAHSALASNQPAGAEVLVDNRDLIAPLELCYQSLHDCGMGVIAEGPLLDCLRRAVTFGLFLGRLDVRQDAARHRDALTEITDYLGLGRYADWDEEQRIGFLQAELKNRRPLLPAHFKPQADTAEVLATCREVAAAPAASLGSYVISMAGAASDVLAVQLLLKEAGLTRPMRVVPLFETLADLDNAGPVMQRLLGLPGYRAGLRGPQEVMIGYSDSAKDAGTTAAAWAQYRAQENLVRICAEHQVELLLFHGRGGTVGRGGGPAHAAILSQPPGSVAGRFRTTEQGEMIRFKFGLPGIAEQNLNLYLAAVLEATLLPPPPPQPAWRELMDQLAADGVKAYRSVVRENPDFVEYFRQSTPEQELGRLPLGSRPAKRRAGGIESLRAIPWIFGWTQTRLMLPAWLGWETALSNALARGQGELLAQMREQWPFFRTRIDMLEMVLAKADAQIAEAYDERLVQPHLLPLGAHLRDLLSQSCQVVLGLTGQPVLLAHSPETLEFISLRNTYLDPLHRLQAELLARSRSREAALDSPLEQALLVTVAGIAAGLRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: SUCC_PSEFS
Sequence: MNLHEYQGKQLFAEYGLPVSKGYAVDTPEAAAEACDKIGGTEWVVKAQVHAGGRGKAGGVKLVRSKEDAKAFAQQWLGKRLVTYQTDANGQPVTKILVESCTDIAKELYLGAVVDRSSRRIVFMASTEGGVDIEKIAEETPEKILKATIDPLVGAQPFQGRELAFQLGLEGKQVAQFAKIFVGLAKLFQDHDLALLEVNPLVIKADGDLHCLDAKINIDANAMYRQPKLKTFHDPSQDDPREAHAAKFELNYVALEGNIGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVTEAFKIILSDSNVAAVLVNIFGGIVRCDMIAEGIIGAVKEVGVKIPVVVRLEGNNAELGAKVLAESGLNIIAATSLTDAAQQVVKAAEGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: BSSC_THAAR
Sequence: MTTCKDCAFFFSIPEDADDFEKSKGDCVTQKDDEKGRYWLSKPVFENDQCCGAFHKR
What is the function of this protein?
Catalyzes the addition of fumarate to the methyl group of toluene, leading to the formation of benzylsuccinate.
What are the official names of this protein?
Benzylsuccinate synthase gamma subunit.
Protein: PAK3_PANTR
Sequence: MSDGLDNEEKPPAPPLRMNSNNRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGGGDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTPDLYGSQMCPGKLPEGIPEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHPSSTKTASEPPLAPPVSEEEDEEEEEEEDENEPPPVIAPRPEHTKSIYTRSVVESIASPAVPNKEVTPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLIIAAKEAIKNSSR
What is the function of this protein?
Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, or cell cycle regulation.  Plays a role in dendrite spine morphogenesis as well as synapse formation and plasticity.  Acts as downstream effector of the small GTPases CDC42 and RAC1.  Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues.  Phosphorylates MAPK4 and MAPK6 and activates the downstream target MAPKAPK5, a regulator of F-actin polymerization and cell migration.  Additionally, phosphorylates TNNI3/troponin I to modulate calcium sensitivity and relaxation kinetics of thin myofilaments.  May also be involved in early neuronal development (By similarity).  In hippocampal neurons, necessary for the formation of dendritic spines and excitatory synapses; this function is dependent on kinase activity and may be exerted by the regulation of actomyosin contractility through the phosphorylation of myosin II regulatory light chain (MLC) (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase PAK 3, Beta-PAK, p21-activated kinase 3, PAK-3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_MYCTU
Sequence: MLRWITAGESHGRALVAVVEGMVAGVHVTSADIADQLARRRLGYGRGARMTFERDAVTVLSGIRHGSTLGGPIAIEIGNTEWPKWETVMAADPVDPAELADVARNAPLTRPRPGHADYAGMLKYGFDDARPVLERASARETAARVAAGTVARAFLRQALGVEVLSHVISIGASAPYEGPPPRAEDLPAIDASPVRAYDKAAEADMIAQIEAAKKDGDTLGGVVEAVALGLPVGLGSFTSGDHRLDSQLAAAVMGIQAIKGVEIGDGFQTARRRGSRAHDEMYPGPDGVVRSTNRAGGLEGGMTNGQPLRVRAAMKPISTVPRALATVDLATGDEAVAIHQRSDVCAVPAAGVVVETMVALVLARAALEKFGGDSLAETQRNIAAYQRSVADREAPAARVSG
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: FTSB_HAEI8
Sequence: MRLLILILLSVLVLFQYNFWFGSNGFLDYRQNAEKIKENQAENEKLSQRNQRINAEIQGLTKGFEAIEERARMQHGLVKENEVFYHIVKESK
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: IF1_STRP3
Sequence: MAKEDVIEIEGKVVETMPNAMFTVELENGHQILATVSGKIRKNYIRILVGDRVTVEMSPYDLTRGRITYRFK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_BURPS
Sequence: MKSTRPFHPTPVITIDGPTASGKGTVAALVAAHLGFHLLDSGALYRLAALASIRYQVEPDDADALASLVDGLHITFREGCAQLDGVDVSDEIRAEAVGNRASAIAVHASVRAALVARQRAFRKTPGLVADGRDMGTVIFPDAVLKVFLTASVEARAARRHKQLMQKGFSANMDNLLQDLRERDARDSNRAAAPLKPAADAKPLDTSALTIEQSVEQVLAWYRELGQPA
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DGTL2_PSEA7
Sequence: MDWQTLLTRERLGKPVHSNDELGRSAFHKDHDRIIFSGAFRRLGRKTQVHPVSSNDHIHTRLTHSLEVACVGRSLGMRVGEILRDELPEWCDPSDLGVIVQSACLAHDIGNPPFGHSGEDAIRNWFQQAAGRGWLDEMSDAERSDFLHFEGNAQGFRVLTQLEYHQFDGGTRLTYATLGTYLKYPWTSRHAESLGYKKHKFGCYQSELPLLEQITQKLGMPQLDDEQWARHPLVYLMEAADDICYGLIDLEDGLEMELLEYSEVEALLLGLVGDDLPDTYRQLGPRDSRRRKLAILRGKAIEHLTNAAARAFVDQQQALLAGRLGGDLVEHMHGPAKLCVQRAKAIAREKIFQDKRKTLHEIGAYTTLEILLNAFCGAALEQYGGHTPSFKSRRILDLLGRNAPDPQWPLYRAFLQVIDFIAGMTDSYATEMAREMTGRSSPV
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 3 subfamily.
Protein: GET1_LODEL
Sequence: MLTLDIDPYTILVTSFLILAIQKLVTVIGKQKIQLYIWQIYTKYLSHSQSIKQFNLKQKEIKDLTKQQKLISAQDEYAKWTKINRALDKLKLEVQELNETIAGEKTRIDSITKLAITLILTLPIWFLRIFCRKTALLYIRKGILPAYLEWWLALPFFKSGTIGLTCWMFVVNSVLSNLIFLISFPFTQKVERPIKPKNEQKTES
What is the function of this protein?
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Together with GET2, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.
What are the official names of this protein?
Golgi to ER traffic protein 1, Guided entry of tail-anchored proteins 1.
What is the protein family that this protein belongs to?
Belongs to the WRB/GET1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: MATK_EICCR
Sequence: MEELQSFLEKDRSWXQHFLYPLLFQEYIYVFAHDHGLNGSIFYEPVNFLGYDKKSSAVLVKRLIIRMYQQNHLICSFNESNRNRFVGHNYYSYFYSLMISEGVSLIVEIPFSLQLKSSIEEIHNLRSIHSIFPFLEDKLSXLNYLXDILIPHPIHMXILVQILQSRSPDAPSLHFLRLFLHQYHNWNSLITPKKSISVISKENKRLFXXLYNSYISECEFLLVFLRKQSSYLPLTSSGVFLERTYYYGKIQRILVWQNFFQKTLWVFKDPXMHYVRYQGKVILGSKGTNFLMKKWKFYFVNLWQYYFHFWSQPCRIHINQLSNYSFYFLGYFSNVLKNPLSVRNQMLENSFLMDTLTKKFDTLVPVIPLISSLSKAKFCTVSGHPISKPIWTDLSDCDIINRFGRICRNLSHYHSGSSKKQSLYRIKYILRLSCARTLARKHKSTVRIFMQRVSSGLLEEFFTEEERVLSLIFPQTTFFSLRGSQRERIWYLDIIRINDLVTNF
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y217_VIBCH
Sequence: MSLKQLPTESMPREKLLQRGPQSLSDAELLAIFLRTGTQGMNVLALADLLLRDFGSLRALFCASKEQFCRHKGLGEAKFVQLQAVLEMTQRYLAETLKRGDALTSPQQTKLYLSSVLRDRQREAFYILFLDNQHRVIRDEILFEGTIDAASVYPREVVKRALHHNAAAVILAHNHPSGVAEPSQADRRITDRLRDALGLVEIRVLDHFVVGDGEVVSFAERGWI
What are the official names of this protein?
UPF0758 protein VC_0217.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: TMC5_MOUSE
Sequence: MSSFHQNSSYMEDADYPGYSGSRNHTHNYLETQDYPEFPGSQNNPGFHHPRSNPHSSGSRTNPDYPYFQEEPDYPGSLSNTVYQDTRSHPFSAHSRTRPDYESSIEPDYNDFRSESYHAGLPMEPDYPGSQSHPGFAGVGRSSMNYTGPRTNLGYLGSLEEPDYPGAQDNSYYHSGSRPHSNLPGSRRDAGYAGSRINSYPDDLGEPDYPGAENQPNSPRFYGKPDYPGAEEGDGYSSSKSLAVIRRGNGPFGMLGRRNEDYPEGIGMVSMEMAGDPRNGYVNPAYTRRISPVCPDRNLLLCAHDWHTSVQGQKLIASLIPMTTRDRIKTIRNQPRTMQEKRELRKIVDKEKNKQSHGILEANCCAQCLGSLSLTYRRTRNGLSELLNYITLWQKRFKVIGGKFGTSVLSYFSFLRWLLKFNIFSFVMNFSFIIIPQFTVGAKNTLQFTGLEFFTGAGYFGDTVMYYGFYTNSTIRHRMGGASYNMQLAYIFTIGACLVVCFFSLLFSMAKYFRNNFINPHIYSRGIAKLIFCWDFTVTHEKAVKLKQKNLSTEIRENLSELRQENYRLTFNQQLTRFSAHVAAWLVSTGVTAACCVAVYYLAEYNSEFLKTHRNPGAVLLLPFVVSCINLAVPRFYSMFRLVERYEIPRQEVYVLLVRNIFLKISIVGILCYYWLNIVALSGEECWETLIGQDIYRLLLMDFVFSLADSLLGEFLRRLIGMKFTSLSLQEFDIARNVLELIYAQTLTWLGIFFCPLLPFIQMITLFIMFYVKNVSLMMNFQPPSKAWRASQMITFFIFLLFFPSFTGVLCTLAITIWRLKPSADCGPFRGLPSFIQSIYSWIDTLSRRPGYLWVVWIYQNLIGSVHFFFILTLIVLIITYLYWQITEGRKVMIRLLHEQIINEGKDKMFLIEKLTKLQDMEKRVNPSALDLERREVEPQIPLHLEELGAAPDLRLRRSAQEENPIA
What is the function of this protein?
Probable ion channel.
What are the official names of this protein?
Transmembrane channel-like protein 5.
What is the protein family that this protein belongs to?
Belongs to the TMC family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RBFA_VIBA3
Sequence: MSKEFSRTQRVSQQLQKELALILQREVRDSRIGMVTISDVEVSRDLAYAKVFVTFLCIGEQTPESCLAALKEHEVPVRMALGKRIRHRLTPEVRFTYDNTLVEGMRMSNLVSEVLNDDKRKQEESGRTDETQSKGEE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSBV_STAA8
Sequence: MNLNIETTTQDKFYEVKVGGELDVYTVPELEEVLTPMRQDGTRDIYVNLENVSYMDSTGLGLFVGTLKALNQNDKELYILGVSDRIGRLFEITGLKDLMHVNEGTEVE
What is the function of this protein?
Positive regulator of sigma-B activity.  Non-phosphorylated RsbV binds to RsbW, preventing its association with sigma-B.  When phosphorylated, releases RsbW, which is then free to complex with and inactivate sigma-B (By similarity).
What are the official names of this protein?
Anti-sigma-B factor antagonist, Anti-anti-sigma-B factor.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-factor antagonist family.