PharMolix/UniProtQA huggingface dataset:
Protein: MRAZ_SALA4
Sequence: MFRGATLVNLDSKGRLTVPTRYREQLIESATGQMVCTIDIHHPCLLLYPLPEWEIIEQKLSRLSSMNPVERRVQRLLLGHASECQMDGAGRLLIAPVLRQHAGLTKEVMLVGQFNKFELWDETTWYQQVKEDIDAEQSATETLSERLQDLSL
What is the function of this protein?
Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster.  Acts by binding directly to DNA.  May also regulate the expression of genes outside the dcw cluster.
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: GRPE_NEIMF
Sequence: MSEQTQQQNSEEAVENVEAVETVETVGNADGVQEQAAAEPAYEDLQARIAELEAQLKDEQLRALANEQNLRRRHQQEIADTHKFAGQKFAVEMLPVKDYLEMALLDQSGNFDALKMGVQMTLNELQKAFDATQIKEINPKAGDKLDPNIHQAMQAVASEQEPNTVVGVMKKGYTLSDRVLRPAMVTVAQKEA
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CFBA_META3
Sequence: MEALVLLGHGSRLPYSKEIVGKVAEKIKEKNIYDIVEIGMMEFNEPTIPQTINKVIAEGAKKIIIVPVFLAHGNHTKRDIPQILGLIECEEHHHEGEGGHHHHHHHHHGEKIEVPEGVEIIYRDPMGADDRVVDIVLDRAKGN
What is the function of this protein?
Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis.  Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation.  Catalyzes the insertion of Ni(2+) into sirohydrochlorin to yield Ni-sirohydrochlorin.
What are the official names of this protein?
Sirohydrochlorin cobaltochelatase, CbiXS, Sirohydrochlorin nickelchelatase.
What is the protein family that this protein belongs to?
Belongs to the CbiX family. CbiXS subfamily.
Protein: RL6_DEHM1
Sequence: MSRIGKMPIKVPPGVTVDIKGNDVTVKGPKGTLNRTFRPEVTITRDGDYLVVAPVGTDKAARSFFGLSRTLLDNMIVGVKDGFDKNLEIVGVGMRADKDGNNIIFKVGYSHTVTVAPPAGITLSVDGTTKVKVSGINKEEVSQMAAEIRSIRKPDHYMGKGIRYAGEYVRIKPGKAIGKGAK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RR11_LOLPR
Sequence: MAKAIPKIGSRKKVRIGLRRNARFSLRKSARRITKGVIHVQASFNNTIITVTDPQGRVVFWSSAGTCGFKSSRKASPYAGQRTAVDAIRTVGLQRAEVMVKGAGSGRDAALRAIAKSGVRLSCIRDVTPMPHNGCRPPKKRRL
What are the official names of this protein?
30S ribosomal protein S11, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RR12_TETOB
Sequence: MPTIQQLIRSARKKVSKKTKAPALKSCAQRRGICLRVYTVTPKKPNSALRKVARVRLTSGFEVTAYIPGIGHNLQEHAVVLVRGGRVKDLPGVRYHIVRGTLDTAGVKNRVQSRSKYGVKLAATKAAAKK
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits (By similarity).
What are the official names of this protein?
30S ribosomal protein S12, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SIR4_MONBE
Sequence: MAATKLHPALRNAIRAGANLPTEVISATFDVQEGIKLLSAFLLRHEPVCVLTGAGISTDSGIPDYRSPGRPPHRPLQHLEFLGSHERQQRYWARSLYGYPRIRDTMPNVGHQAINELQRRGLVGAIITQNVDGLHQRAGSQHVIDLHGRLDQVKCMNCHSITTRDELQSRLLADNKALLDQFSVVHDEAVRPDGDAVLDEDLYGRFTVAACASCGGVLKPNVVFFGGSLDPEDVKRASTAVSEASALFVVGTSLATWSAFRIVRQAVEEAKPVCVLNSGPTRADGVIPEYLRLCMPIGEVLPAALRQL
What is the function of this protein?
NAD-dependent protein deacylase.  Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues.
What are the official names of this protein?
NAD-dependent protein deacylase SIR4, Regulatory protein SIR2 homolog 4.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class II subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: LEXA_LISW6
Sequence: MKISKRQQDIYEFIKSEVKEKGYPPSVREIGEAVGLASSSTVHGHLARLEGKGLIRRDPTKPRAIEILSLEDEAETPNVVNIPIIGKVTAGMPITAIENIEEYFPLPEYMAAGETNVFMLEIDGESMINAGILDGDKVIVRQQNSAINGEIVVAMTDENEATCKRFYKEANHFRLQPENDALEPIILNNVTILGKVIGLYRDIR
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: PGK_THET8
Sequence: MRTLLDLDPKGKRVLVRVDYNVPVQDGKVQDETRILESLPTLRHLLAGGASLVLLSHLGRPKGPDPKYSLAPVGEALRAHLPEARFAPFPPGSEEARREAEALRPGEVLLLENVRFEPGEEKNDPELSARYARLGEAFVLDAFGSAHRAHASVVGVARLLPAYAGFLMEKEVRALSRLLKDPERPYAVVLGGAKVSDKIGVIESLLPRIDRLLIGGAMAFTFLKALGGEVGRSLVEEDRLDLAKDLLGRAEALGVRVYLPEDVVAAERIEAGVETRVFPARAIPVPYMGLDIGPKTREAFARALEGARTVFWNGPMGVFEVPPFDEGTLAVGQAIAALEGAFTVVGGGDSVAAVNRLGLKERFGHVSTGGGASLEFLEKGTLPGLEVLEG
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCME2_PSEPF
Sequence: MNPLRKKRLVIILAILVGVGAAVGLALSALQQNINLFYTPTQIANGEAPKDTRIRAGGMVEKGSLVRSGDSLDAKFNVTDFNKTVTITYRGILPDLFREGQGIVALGKLNADDVVVADEVLAKHDEKYMPPEVAKALKDSGQSAPAPGKEG
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE 2, Cytochrome c maturation protein E 2, Heme chaperone CcmE 2.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: WAPC_OXYMI
Sequence: MSSGGLLLLLGLLTLWAEVTPISGQDRPKKPGLCPPRPQKPCVKECKNDWSCPGQQKCCNYGCIDECRDPIFVN
What is the function of this protein?
Damages membranes of susceptible bacteria.  Has antibacterial activity against the Gram-positive bacteria B. megaterium and S. warneri.  After 45 minutes of treatment with this protein, B. megaterium have no visible pili and are smooth.  Has no antibacterial activity against the Gram-positive bacteria B. thuringiensis, S. aureus, S. clavuligerus and B.  anthracis, or the Gram-negative bacteria E. coli and A. tumefaciens.  Has no hemolytic activity.  Does not inhibit the proteinases elastase and cathepsin G.  Is not toxic to mice.
What are the official names of this protein?
Omwaprin-c, Oxywaprin-c.
What is the protein family that this protein belongs to?
Belongs to the snake waprin family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y381_PSYIN
Sequence: MIYSTTETIPGKEITEIVGVVTGNVVQAKHIGRDIMAGLKSIVGGEIRGYTEMLTEARDLAIQRLVASANEKGADAVVGIRFTTSAIMDGSSEIMAFGTAVKLKK
What are the official names of this protein?
UPF0145 protein Ping_0381.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: PANC_BRUA1
Sequence: MQIIHTIEELRQALAPARQQGKKIGFVPTMGYLHKGHLELVRRARVENDVTLVSIFVNPLQFGANEDLGRYPRDLERDAGLLHDAQVDYLFAPTVSDMYPRPMQTVVDVPPLGNQIEGEARPGHFAGVATVVSKLFNIVGPDAAYFGEKDFQQLVIIRRMVDDMAIPVRIVGVETVREDDGLACSSRNVYLTPEQRRAAIIVPQALDEADRLYRSGMDDPDALEAAIRTFIGRQPLAVPEVIAIRDPETLERLPALQGRPILVALFVRVGATRLLDNRVIGHAAPQITQERAA
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VG38_BPOX2
Sequence: MAVVGVPGWIGSSSVNETGQRWMSQAAGQLRLGVPCWMSQFAGRSREIIHTLGADHNFNGQWFRDRCFEAGSAPIVFNITGDLVSYSKDVPLFFMYGDTPNEYVVLNIHGGVHMWGRGGNGGYTHSGGDGNGTQGGHVIQNDIGGRLRIWNYGVIAAGGGGGGGIAYRPHSGAKWQDIGGGGGRPFGGAGGGRYSGGAASYEGPGGGYDYGNAHSGAGGNAGAAGQNAWSDGGKVLKVGVGGASGHAVFGSSPTWGVVGTIYGPRV
What is the function of this protein?
Vg38 is at the tip of the long tail fibers and serves as the phage recognition site for the cellular receptor.
What are the official names of this protein?
Receptor-recognizing protein, Protein Gp38.
What are the subcellular locations of this protein?
Virion.
Protein: APBA2_HUMAN
Sequence: MAHRKLESVGSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEEQECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEEYLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQEEDGHYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMTSITSASEASPEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGFKPKTRTPEERLKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGPCEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANSEGDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSASQDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQKEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSVGEIHMKTMPAAMFRLLTGQETPLYI
What is the function of this protein?
Putative function in synaptic vesicle exocytosis by binding to STXBP1, an essential component of the synaptic vesicle exocytotic machinery.  May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta.
What are the official names of this protein?
Amyloid-beta A4 precursor protein-binding family A member 2, Adapter protein X11beta, Neuron-specific X11L protein, Neuronal Munc18-1-interacting protein 2, Mint-2.
Protein: MTNN_VIBCM
Sequence: MKIGIIGAMQQEVAILKDLIEDVQEVNQAGCTFYSGQIQGVDVVLLQSGIGKVSAALGTALLISQYAPDVVINTGSAGGFDASLNVGDVVISSEVRHHDADVTAFGYEIGQMAGQPAAFKADEKLMTVAEQALAQLPNTHAVRGLICTGDAFVCTAERQQFIRQHFPSVVAVEMEASAIAQTCHQFKVPFVVVRAISDVADKESPLSFEEFLPLAAKSSSAMVLKMVELLK
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: RLMH_PROMH
Sequence: MKLQLIAVGTKMPDWIQTGFMDYLNRFPKDMPLELIEIPAGKRGKNADIKRILEKEGEQMLAAVGKGNRIVTLDIPGARWDTPKLAEQLDRWKLDGRNVSLLIGGPEGLAPACKAAAEQSWSLSPLTMPHPLVRVVVAESLYRAWSITTNHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNM51_LIGS5
Sequence: MNENDKMKIKEVIVVEGKDDTKRIQMAVNADTLETRGSAISDETLDQIEDLYDKRGVIVFTDPDFSGEKIRKIITEAVPGVKHAFLTKHDAAPSHKGSLGVEHASPEAIREALAHLYTEVPDGEPLISREDLAVAGLTSGPQAKEYRRRLGEYLRIGYTNGKQLYKRLKLFQITPDELKKALEYIKNEDNY
What is the function of this protein?
Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor.  Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.
What are the official names of this protein?
Ribonuclease M5 1, RNase M5 1, Ribosomal RNA terminal maturase M5 1.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease M5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS_STRZJ
Sequence: MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAAQILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTLVCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQTASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLFWLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYDIERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELESLISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTLKIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSANLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQIDIRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQLGSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDELGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQDGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQTSAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: PEX12_DICDI
Sequence: MFMFNFDNGHDPNRPSFFEMLNQHQMMPSFKPALKYIFTVLSQRNPKFRYIVNYYDECFYSLLLLLEYHYLKYYEGSFSENFYNLKRIKPRNNNANGDGDTLFSLLKRLVVTPSNAGQGPETYTKSQILKKSFAMIRRNRAAASSSQQAKDDLNTMIQDSDRKESLIYLVLIPYFKGKLDEYYKKESDPLAELGLVSSDNNNNNNDNINDQIQQLEEQIQQQQTIVNGNNNSNNNNKKLKIKFLILIRFLKGSKTLKKLKTIFLKVYPFISAIYEALFFIYQLLYLYEYTNYYTPFFHFQNIQLKRLNHKDIESHRVVISNRRRDRINFVRDWPGSSFFVRLVSILDSILDYSKYILPLSVFIFKSLEWWYSENRISAPTLPIPTPPTPSKRAPGGLEIPRDKRLCPLCLKERTNPTICGSGFVFCYPCIFGYVNEHSKCPITFLPTNTEQLRKIYETV
What is the function of this protein?
Component of a retrotranslocation channel required for peroxisome organization by mediating export of the PEX5 receptor from peroxisomes to the cytosol, thereby promoting PEX5 recycling (By similarity).  The retrotranslocation channel is composed of PEX2, PEX10 and PEX12; each subunit contributing transmembrane segments that coassemble into an open channel that specifically allows the passage of PEX5 through the peroxisomal membrane (By similarity).  PEX12 also regulates PEX5 recycling by activating the E3 ubiquitin-protein ligase activity of PEX10 (By similarity).  When PEX5 recycling is compromised, PEX12 stimulates PEX10-mediated polyubiquitination of PEX5, leading to its subsequent degradation (By similarity).
What are the official names of this protein?
Putative peroxisome assembly protein 12, Peroxin-12.
What is the protein family that this protein belongs to?
Belongs to the pex2/pex10/pex12 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Single-pass membrane protein.
Protein: RL35_AROAE
Sequence: MPKMKTKSGAAKRFKVRASGGIKRSQAFKRHILTKKTTKSKRQLRGMTGVHAADEKLIRAMLPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: KUP_LACCB
Sequence: MASGLTANKKLRHKITAAALLVTLGVVYGDIGTSPLYVMKSIVAGNGGMGHFDTDFLVGSVSLIFWTLLIITTVKYVLIALRADNNGEGGIFALYTLVRQRARWLVLPAMVGGAALLADGMLTPAVTVTTAIEGLKGVHINGNILIDNQQQVIWVTILIITFLFFIQRFGTDLIGKAFGPIMFVWFTFLGVAGFIALSKDWSMLRALNPYYALHLLVSPDNKMGLFILGSIFLATTGAEALYSDMGHVGRGNIYLSWPYVNICLVLNYFGQAVWLDQNSKVTAFNKITDFNPFFQMLPESIRLGAIILATLAAIIASQALISGSYTLVSEAIKLRFLPRLHIIYPTRLKGQLYIPVVNTILWLACLAIIGYFKTSAEMEGAYGLAITITMLMTTLLLYQYLRSRHAPAVIAIGTLIFFSAIETVFFISSAVKFLHGGYVTAMIAFIILAVMYVWQYGGRIRDDNTYRAEMASLFAYKNQLSELRNDPDYPTYTTNLVYMTQIANDHYIKKEILYSILDKRPKRARVYWFVTVNVTDEPYTAEYTTDTYGTDYMVNVQLYLGFRMEQQVNVFLRQIVNDMMREGELPTQPQKYTTIPDRQVGDWTFVLLHEELSPQTQIKGFQKAIIQARLRLQHIAVSPAQWFGLEYADTIDETVPLVLGKIPITKLNRLTRSQAEAQPEDEDD
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: R18A3_ARATH
Sequence: MGGFRFHQYQVVGRALPTENDEHPKIYRMKLWGRNEVCAKSKFWYFMRKLKKVKKSNGQMLAINEIFEKNPTTIKNYGIWLRYQSRTGYHNMYKEYRDTTLNGGVEQMYTEMASRHRVRFPCIQIIKTATVPAKLCKREITKQFHNSKIKFPLVFRKVRPPSRKLKTTYKASKPNLFM
What are the official names of this protein?
60S ribosomal protein L18a-3.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL20 family.
Protein: YD187_YEAST
Sequence: MQVASILQVRPPFFPQIHFLLFFFCFFVSKSRVASQRGTHFLVRICFEPPLQGCRMGKLCRPHLNHLLYLCYTAYFSNISWLSVSKSTSRNRVHKYIPYKSTELRSVAN
What are the official names of this protein?
Putative uncharacterized protein YDL187C.
Protein: EPHA7_RAT
Sequence: MVVQTRYPSWIILCYIWLLGFAHTGEAQAAKEVLLLDSKAQQTELEWISSPPSGWEEISGLDENYTPIRTYQVCQVMEPNQNNWLRTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNLYYYETDYDTGRNIRENLYVKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSKKGFYLAFQDVGACIALVSVKVYYKKCWSIIENLAVFPDTVTGSEFSSLVEVRGTCVSSAEEEAENSPRMHCSAEGEWLVPIGKCICKAGYQQKGDTCEPCGRRFYKSSSQDLQCSRCPTHSFSDREGSSRCECEDGYYRAPSDPPYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGECVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQAAPSQVSGVMKERVLQRSVELSWQEPEHPNGVITEYEIKYYEKDQRERTYSTLKTKSTSASINNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEASGKMFEATAVSSEQNPVIIIAVVAVAGTIILVFMVFGFIIGRRHCGYSKADQEGDEELYFHFKFPGTKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPSSLKTPLGTCSRPISPLLDQSTPDFTAFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTIDDVMSLGITLVGHQKKIMSSIQTMRAQMLHLHGTGIQV
What is the function of this protein?
Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.  The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling.  Among GPI-anchored ephrin-A ligands, EFNA5 is a cognate/functional ligand for EPHA7 and their interaction regulates brain development modulating cell-cell adhesion and repulsion.  Has a repellent activity on axons and is for instance involved in the guidance of corticothalamic axons and in the proper topographic mapping of retinal axons to the colliculus.  May also regulate brain development through a caspase(CASP3)-dependent proapoptotic activity.  Forward signaling may result in activation of components of the ERK signaling pathway including MAP2K1, MAP2K2, MAPK1 and MAPK3 which are phosphorylated upon activation of EPHA7.
What are the official names of this protein?
Ephrin type-A receptor 7, EPH homology kinase 3, EHK-3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: MBCA_MYCBO
Sequence: MGVNVLASTVSGAIERLGLTYEEVGDIVDASPRSVARWTAGQVVPQRLNKQRLIELAYVADALAEVLPRDQANVWMFSPNRLLEHRKPADLVRDGEYQRVLALIDAMAEGVFV
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system.  Neutralizes the activity of cognate toxin MbcT by blocking access to the toxin active site.
What are the official names of this protein?
Mycobacterial cidal antitoxin MbcA.
What is the protein family that this protein belongs to?
Belongs to the MbcA/ParS/Xre antitoxin family.
Protein: LEU3_GEOKA
Sequence: MGNYRIAVLPGDGIGKEVTSGAVEVLKAVGIRFGHEFTFEYGLIGGAAIDEAGTPLPEETLRLCRESDAVLLGAVGGPKWDDNPPHLRPEKGLLAIRKQLDLYANLRPVVCYDSLVSASPLKPDLVQGVDFVIVRELTGGIYFGQPSGRVVENGEEKAVDTLLYKKEEIERIVRMAFILARGRKKKVTSVDKANVLSSSRLWREVAEEVAKQFPDVTLEHMLVDNAAMQLIRAPKQFDVIVTENMFGDILSDEASMLSGSLGMLPSASLSASGPSLYEPVHGSAPDIAGMNKANPIAAILSAAMMLRLSFGLTAEAEAVEHAVRQALDQGLRTADLAPSGGRIVSTNEMVEEIKTAVLDYTAIAQIMTVYA
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTJ_YERPN
Sequence: MIYWIFLGLAIIAEIIGTLSMKYASVSGEMTGHIVMYFMITGSYVMLSLAVKKVALGVAYALWEGIGILIITIFSVMWFGETLSPLKIAGLVTLIGGILLVKSGTRKPKQPNCHRGNRPPSVQELKTQTTGHHKGVAVESGEHHAAA
What is the function of this protein?
Catalyzes the excretion of spermidine.
What are the official names of this protein?
Spermidine export protein MdtJ.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtJ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ROCA_GEOSW
Sequence: MVQPYKHEPLTDFTVEANRKAFEEALKKVEAELGKDYPLIIGGERVTTDEKIVSINPANKTEVIGRVSKANKELAEKAMKVADEAFKWWSKTKPEARADILFRAAAIVRRRKHEFSALMVKEAGKPWKEADADTAEAIDFMEYYARQMLKLKDGVPVESRPGETNRFFYIPLGVGVVISPWNFPFAIMAGTTVASLVTGNTVLLKPASATPVVAYKFAEVLEEAGLPAGVLNYIPGSGAEVGDYLVDHPRTRFISFTGSRDVGIRIYERAAKVHPGQIWLKRVIAEMGGKDGIVVDKEADLELAAQSIVASAFGFSGQKCSACSRAIIVEDVYDQVLNRVVELTKQLKVGDPADQSTFMGPVIDQSAYNKIMEYIEIGKKEGRLMTGGEGDDSKGFFIQPTVFADVDPNARIMQEEIFGPVVAFTKAKDFDHALEIANNTEYGLTGAVISRNRANLEKAREEFHVGNLYFNRGCTGAIVGYQPFGGFNMSGTDSKAGGPDYLILHMQAKTVSEMF
What are the official names of this protein?
1-pyrroline-5-carboxylate dehydrogenase, P5C dehydrogenase, L-glutamate gamma-semialdehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. RocA subfamily.
Protein: SIM23_HUMAN
Sequence: MATQQVDSRRQVAAEQVAAQLLERRRGSHCDDEKQTLLALLILVLYLSTEIWGSSWEVSERIRECNYYQNLAVPQGLEYQTNEPSEEPIKTIRNWLKEKLHVFSEKLEEEVQQLEQLAWDLELWLDALLGEPHQEEHCSTYKSHLWEWAWALGREHKGGEGLLEISLSGAEL
What are the official names of this protein?
Small integral membrane protein 23.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.