PharMolix/UniProtQA huggingface dataset:
Protein: SCX1_TITTR
Sequence: MKGMILFISCILLIGIVVECKEGYLMDHEGCKLSCFIRPSGYCGRECAIKKGSSGYCAWPACYCYGLPNWVKVWERATNRCGKK
What is the function of this protein?
Beta toxins modify sodium channel function in two ways: an excitatory effect (shifting the activation process to more negative potential) and/or a depressant effect (reducing the peak current).  At concentration of 500 nM this toxin produces channel opening at more negative potentials in hNav1. 2/SCN2A and hNav1. 3/SCN3A, which shows the biggest effect.  On the other hand the peak current is decreased in hNav1. 4/SCN4A and hNav1. 5/SCN5A channels, without apparent modification of the activation gate.  This toxin is active against mammals.
What are the official names of this protein?
Beta-mammal Tt1g, T.trivittatus toxin 1 gamma-like.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HPRK_PROA2
Sequence: MNLDQKGLKKRSMTVAYFFENISKSLDIKLRRLNEVDEQKRRIFERDLHRPGLALAGFTNLFTYKRVQILGNTETRFLNHLEDDDRKRAFESLIKFKLPCIILTSNNKLEPELLDMATRAGVPVFVTRHSSTKTIYLLTDFLDDQFSQYQQFHGSMVDVYGVGVMLIGNSGLGKSEVALDLVERGHRLVADDAVVINRKGENVLIASGNEIVDHFMEIRGLGVVDVKAIFGIRAIRDKKVVQVVVELLEWNEESDYERLGLDTKTTKILGVDIPLIQLPINPGKNITVIIEVVALNYLLKHYSGYVAAEALEQRIKRVITNESLKKSGKGRTYLAKDYEE
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: CHIB_ARAHY
Sequence: MTAQGNKPSSHDVITGRWTPSAADKAAGRVSGFGVITNIINGGLDC
What is the function of this protein?
Defense against chitin-containing fungal and bacterial pathogens.
What are the official names of this protein?
Endochitinase 1B, CHIT 1B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 19 family. Chitinase class I subfamily.
Protein: SGBU_HAEIN
Sequence: MKKHKIGIYEKALPKNITWQERLSLAKACGFEFIEMSIDESNDRLSRLNWTKSERIALHQSIIQSGITIPSMCLSAHRRFPFGSKDKKIRQKSFEIMEKAIDLSVNLGIRTIQLAGYDVYYEKQDEETIKYFQEGIEFAVTLAASAQVTLAVEIMDTPFMSSISRWKKWDTIINSPWFTVYPDIGNLSAWNNNIEEELTLGIDKISAIHLKDTYPVTETSKGQFRDVPFGQGCVDFVHFFSLLKKLNYRGAFLIEMWTEKNEEPLLEIIQARKWIVQQMEKAGLLC
What is the function of this protein?
Catalyzes the isomerization of L-xylulose-5-phosphate to L-ribulose-5-phosphate.
What are the official names of this protein?
Putative L-ribulose-5-phosphate 3-epimerase SgbU, L-xylulose-5-phosphate 3-epimerase.
What is the protein family that this protein belongs to?
Belongs to the L-ribulose-5-phosphate 3-epimerase family.
Protein: PFP2_TRIV3
Sequence: MSTEAPVLGILCGGGPAPGLNGVIAGATLYALRLGWKVIGFMEGFKYLCTGDIETVKAHTIDLTYDIVSRIHFQGGTIIQTSRANPRKSTELQENVRKCLRALKVRYFLTIGGDDTASSAVSVAQGMDGNEISVISCPKTIDNDLPLPADQSTFGFHTARSLGMEIIRNLMVDSKSAPRWFLVEAMGRSAGHLALGMAEASGAHLCLIPEEFKQDEIEFEDVVELVEATILKRLAYGKNYGVCVLAEGLVSKMSKKALYRLFGNREPPTDPHGHILLDDAELARSLSEELLKRLGNLGIRITPKKIGYELRCADPVAFDAVYTRELGYGAIDAFLNGHSAALIVRENGQVKPVQFKDLLDPATGRVRTRLVDVTSQSFKVARVYMWRMSKKDYENKDLVARVAAAGKMTPEAFTEKFAHLTDVVIE
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis.  Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis.  Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
What are the official names of this protein?
Pyrophosphate--fructose 6-phosphate 1-phosphotransferase 2, 6-phosphofructokinase, pyrophosphate dependent 2, PPi-dependent phosphofructokinase 2, PPi-PFK 2, Pyrophosphate-dependent 6-phosphofructose-1-kinase 2.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Short' sub-subfamily.
Protein: XERC2_RALSO
Sequence: MKPAGPRKRAVDPLAHLVLTRYMEAHFEALLVTGYSADTVRARRISIRRFIVWCEERGIAQPADVTRAVLERYQRHLFYYRKPNGAPLTLGSQHGALAPLKTWFKWLARENHILYNPASELDLPKLPKHLPRAILSVQEVEAILAEADPATPYGLRDRAMLELLYSTGIRRMEVAGLALYDVDATRRLAFVRDGKGAKDRVVPVGVRALAWLDRYLLEARPQLIVAEREALFVTDYGEPVSPEYVASRVKRYMEFAGIQKPGATHLLRHAMATHMLEAGADVRVLQALLGHAQLNTTEIYTHVSIEHLRAIHDATHPARLQREDVLAADATDAARQALADALDRDEG
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.
What are the official names of this protein?
Tyrosine recombinase XerC 2.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEPD7_XENTR
Sequence: MATVREKAVSLNLCATYSPAQRPPGPNGSHRPFRATYIWSSIIQALTQVEVKKRRHHLKYHHDCFIGSEAVDVVFAHLVQHKYFGDTEIPRSKVVRVCQALMDCKVFEPIVTACMFGREKKRTVFEDSSCSLYRFINNSSHLGAQVEKSNGRCTPQRPKHSSFQSAPLKSPSLEDLWDNLSLTAADPTHINLTANLPPKVVGEVWQEQTIRRLLQLVDLPLLDSLLEYTPVAPRIPQVKEEELNLTSNYLDREILKAFSDAQADEWVSAAVDCLDFLPDHMVVDVSRNLPEQQAPDSKWKLLLFDTIGKHYQNRSPLLRNQLFDIHTGIAELLVNGKNEPALEATQLCLKLLDSPSREEFRRLLYFMALAADPSEFRLHEETDNRMTVKRMFSRAVVCNKNLSKGKCDLLVLFILDHHKDVFKIPGSLHKMVSDKLVAIQQGSDPDRDTGYTFCQRVDKREFDSATQNNTRTELCALLKTIYENTSLSPKEKKRLLGQFYKSHPETFIQYFGDRVSSVYT
What are the official names of this protein?
DEP domain-containing protein 7.
What is the protein family that this protein belongs to?
Belongs to the DEPDC7 family.
Protein: QUEC_NEIMF
Sequence: MSNQKALVIFSGGQDSTTCLIQAIQIYGRENVQAITFQYGQRHAVELERARWIAQDLGVKQTVLDLSLMRQITHNALMDDTAAIETAENGVPNTFVDGRNALFLLYAAIYAKGQGIRHIIAGVCETDFSGYPDCRDVFVKSMNVTLNLAMDYDFQIHTPLMYLTKAQTWALADEMGVLDYIREQTHTCYNGIVGGCRECPSCILRERGLAEYLESKKAV
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: SYR_LISMO
Sequence: MNVMQENQIKLIEHIKQAVVQAVGLEETEVPEILLEVPKDKKHGDYSTNIAMQLARVAKKAPRQIAESIVPELKKDNKLIKEVEIAGPGFINFYLDNAYLTDLVPVILTEDKKYGESDFGKGEKFQIEFVSANPTGDLHLGHARGAAIGDSLANIMKMAGFDVSREYYINDAGNQINNLVLSAEARYFEALGLESEFPEDGYRGADIISLGKDLAAKYGDKYVHTSEEERRSIFRVDALAFETGKLRADLEEFRVSFDEWFSETSLYEENKVLPALERLRENGYIYEQDGATWLRTTDFEDDKDRVLIKSDGSYTYFLPDIAYHLNKLERGFDVLIDIWGADHHGYIPRMRAAIEALGYSPNQLEVEIIQLVHLFEDGVQVKMSKRTGKSVTMRDLIEEVGLDATRYFFAMRSSDTHMNFDMSLAKSTSNDNPVYYVQYAHARISSILRSGKEQGLEVTKDADMSLLQTEAEYDLLKVLGEFADVVAEAAAKRAPHRIVRYLNDLASAFHRFYNSNKVLDMDNLEVTKARLALIKTAQITLRNGLTLLGVSAPEKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIC_YERPY
Sequence: MFIGDASILKPIQWCATEHPELPADIADWLMELGSMTRRFEQHCQRVHVEPQRECFITRDALGEEAEHLPVSQRYWLREIVLFGDNVPWLLGRTVIPEETLSGPDRALVDLGTLPLGRYLFSGDALTRDYIHVGRQDNLWARRSLLRLSGNPLLLTEVFLPASPLYTHCDSIPK
What is the function of this protein?
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
What are the official names of this protein?
Chorismate pyruvate-lyase, CL, CPL.
What is the protein family that this protein belongs to?
Belongs to the UbiC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLF2_PONAB
Sequence: MTRRCMPARPGFPSSPAPGSSPPRCHLRPGSTAHAAAGKRTESPGDRKQSIIDFFKPASKQGRHMLDSPQKSNIKYGGSRLSITGTERFERKLSSPKKSKTKRVPPEKSPIIEAFMKGVKEHHEDHGIHESCRPCVSLASKYLAKGTNIYVPSSYHLAKEMKSLKKNHRSPERRKSLFIHENNEKNDRDRGKTNADSKKQTTVAEADIFKNSSRSLSSRSSLSRHHPGESPLGAKFQLSLASYCRERELKRLRKEQMEQRINSENSFSEASNLSLKSSSIERKYKPRQEQRKQNDVIPGKNNLSNVENGHLSRKRSSSDSWEPTSAGSKQNKFPEKRKRNSVDSDLKSTRESMIPKARESFLEKRPDGPHQKEKFIKHIALKTPGDVLRLEDISKEPNDETDCSSAGLAPSNSGSSGHHSTRNSDQIRVAGTKETKMQKPHLPLSQEKSAIKKASNLQKNKTTSSMTKEKETKLPLLSHVPSAGSSLVPLNAKNCALPVSKKDKERSSSKECSGHSTESTKHKEHKAKTNKADSNVSSGKISGGPLCSEYGAPTKSPPAALEVVPCVPSPAAPSDKAPSERESSGNSNAGSSALKRKLRGDFDSDEESLGYNLDSDEEEETLKSLEEIMALNFNQTPATTGKPPALSKELRSQSSDYTGHDHPGTYTNTLERLVKEMEDTQRLDELQKQLQEDIRQGRGIKSPIRIGEEDSTDDEDGLLEEHKEFLKKFSVTIDAIPDHHPGEEIFNFLNSGKIFNQYTLDLRDSGFIGQSAVEKLILKSGKTDQIFLTTQGFLTSAYHYVQCPVPVLKWLFRMMSVHTDCIVSVQILSTLMEITIRNDTFSDSPVWPWIPSLSDVAAVFFNMGIDFRSLFPLENLQPDFNEDYLVSETQTTSRGKESEDSSYKPIFSTLPETNILNVVKFLGLCTSIHPEGYQDREIMLLILMLFKMSLEKQLKQIPLVDFQSLLINLMKNIRDWNTKVPELCLGINELSSHPHNLLWLVQLVPNWTSRGRQLRQCLSLVIISKLLDEKHEDVPNASNLQVSVLHRYLVQMKPSDLLKKMVLKKKAEQPDGIIDDSLHLELEKQAYYLTYILLHLVGEVSCSHSFSSGQRKHFVLLCGALEKHVKCDIREDARLFYRTKVKDLVARIHGKWQEIIQNCRPTQGQLHDFWVPDS
What is the function of this protein?
Plays a role in the DNA damage response (DDR) pathway by regulating postreplication repair of UV-damaged DNA and genomic stability maintenance.  The SLF1-SLF2 complex acts to link RAD18 with the SMC5-SMC6 complex at replication-coupled interstrand cross-links (ICL) and DNA double-strand breaks (DSBs) sites on chromatin during DNA repair in response to stalled replication forks.  Promotes the recruitment of the SMC5-SMC6 complex to DNA lesions.
What are the official names of this protein?
SMC5-SMC6 complex localization factor protein 2.
What is the protein family that this protein belongs to?
Belongs to the FAM178 family.
What are the subcellular locations of this protein?
Nucleus. Note=Mainly localizes in the nucleus. Colocalizes with PCNA on replication sites. Associates with chromatin. Accumulates with RAD18 and the SMC5-SMC6 complex at replication-coupled DNA interstrand repair and DNA double-strand breaks (DSBs) sites on chromatin in a ubiquitin- dependent manner.
Protein: RCA2_LARTR
Sequence: MAAAYSTVGAVNRAPLSLNGSGARASLVPSTAFFGSSLKKSAAKFPKASSGNFKIVAQEISEDQQTDKDKWKGLAYDISDDQQDITRGKGMVDTLFQAPMQSGTHYAVMSSYDYISQGLRQYNLDNNMDGFYIAPAFMDKLVVHITKNFLSLPNIKIPLILGIWGGKGQGKSFQCELVFAKMGINPIMMSAGELESGNAGEPAKLIRQRYREAADIIKKGKMCCLFINDLDAGAGRMGGTTQYTVNNQMVNATLMNIADNPTNVQLPGMYNKEENPRVPIIVTGNDFSTLYAPLIRDGRMEKFYWAPTREDRIGVCKGIFRTDNVPEEDIVKVVDQFPGQSIDFFGALRARVYDDEVRKWVSEVGVDTIGKKLVNSKEGPPTFEQPKMTIDKLLQYGNMLVEEQENVKRVQLADKYMSEAALGDANQDAIKRGTF
What is the function of this protein?
Activation of RuBisCO (ribulose-1,5-bisphosphate carboxylase/oxygenase; EC 4. 1. 1. 39) involves the ATP-dependent carboxylation of the epsilon-amino group of lysine leading to a carbamate structure.
What are the official names of this protein?
Ribulose bisphosphate carboxylase/oxygenase activase 2, chloroplastic, RA 2, RuBisCO activase 2, RuBisCO activase beta form.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO activase family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: GATC_PARMW
Sequence: MSRISADDVRKVAKLARLDLPEEKIATYTGQLESILEYVGQLESIDTEGVPETTRAVEVTNVTREDGVTPTPVREDILNQAPQREGDFFRVPKILAD
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: COAX_PELTS
Sequence: MILVFDVGNTNIVLGVFSGSRLVANWRLSTDRYRTSDEYGIMLRELFAFSGLEMKQIKAVVVSTVVPPLTFTLERLCQKYFNLTPLVVGPGIKTGLSIKIDNPREVGADRIVNAVAGYEQYGGPLVIVDFGTATTFCAVSARGEYLGGAIAPGISISTEALFARAAKLPRVEVVKPLSVIGRNTVASMQAGIFYGFVGQVDEIVKRMKKELGENTRVIATGGLAGLIAQESATIEQVDPFLTLKGLRLIYERNAQR
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIKE_BRUME
Sequence: MSLISADNIVKIYQSHSLVGASARKTMLHDISISIGQGETVALLGRSGCGKSTLARLLVGLERPTSGEVRFRGVPLTKLDRSGMKAFRREVQLIFQDSPGAVNARSSVRAIIGEPLRHLTSLDETRREERIQELLRLVELPPEIADRLPAQVSGGQLQRICIARALAVNPKLIILDEAVSNLDIHLQASALALLTKLQQEGGIAYLFVTHDLRLVQKFAARCLVMDEGQIVEEIKTADLDSMRHPASRLLREAVLPPLPVRAVETN
What is the function of this protein?
Part of the ABC transporter complex NikABCDE involved in nickel import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Nickel import ATP-binding protein NikE.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RHAT_KLEP3
Sequence: MNHAITMGIFWHLIGAASAACFYAPFKKVKHWSWETMWSVGGIVSWLILPWAISATLLPDFWAYYRSFNASTLLPVFLFGAMWGIGNINYGLTMRYLGMSMGIGIAIGITLIVGTLMTPIINGQFSVLMHTQGGQMTLLGVLVAVIGVGIVTRAGQLKERKMGIKAEEFNLKKGLLLAVMCGIFSAGMSFAMNAAKPMHDAAAALGVDPLYAALPSYVVIMGGGALVNLGFCFIRLAKVKNLSVKADFSLAKPLIISNLLLSALGGLMWYLQFFFYAWGHASIPAQYDYMSWMLHMSFYVLCGGLVGLVLKEWNNAGRRPVSVLSLGCVVIIIAANIVGLGMAS
What is the function of this protein?
Uptake of L-rhamnose across the cytoplasmic membrane with the concomitant transport of protons into the cell (symport system).
What are the official names of this protein?
L-rhamnose-proton symporter, L-rhamnose-H(+) transport protein.
What is the protein family that this protein belongs to?
Belongs to the L-rhamnose transporter (TC 2.A.7.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LIS1_DROER
Sequence: MKMVLSQRQREELNQAIADYLGSNGYADSLETFRKEADLSTEVEKKFGGLLEKKWTSVIRLQKKVMELEAKLTEAEKEVIEGAPTKNKRTPGEWIPRPPEKFSLTGHRASITRVIFHPIFGLMVSASEDATIRIWDFETGEYERSLKGHTDSVQDVAFDAQGKLLASCSADLSIKLWDFQQSYECIKTMHGHDHNVSSVAFVPAGDYVLSASRDRTIKMWEVATGYCVKTYTGHREWVRMVRVHIEGSIFATCSNDQTIRVWLTNSKDCKVELRDHEHTVECIAWAPEAAASAINEAAGADNKKGHHQGPFLASGSRDKTIRIWDVSVGLCLLTLSGHDNWVRGLAFHPGGKYLVSASDDKTIRVWDLRNKRCMKTLYAHQHFCTSIDFHKAHPYVISGSVDQTVKVWECR
What is the function of this protein?
Positively regulates the activity of the minus-end directed microtubule motor protein dynein.  May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end.  Required for several dynein- and microtubule-dependent processes.
What are the official names of this protein?
Lissencephaly-1 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LIS1/nudF family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localizes to the plus end of microtubules and to the centrosome.
Protein: RS4_ONYPE
Sequence: MSRYTGSLWKVSRRLNYSVSETGKELRKRAYGPGQHGQKKLKLSDYGLQLQEKQKLRFTYGVSEKQFRKTFDNASKLKGIHGEMFLVLLESRLDNVVYRLGFAKTRAQARQLANHGHILVDGKKVDIASYRLKPGQTVTLREKSKNLNIVQEAVNSKFVRADYVSLDKELVGKYVRYPQRNEFLPDINEQLIVEYYNR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: TUSC_ECOL5
Sequence: MKRIAFVFSTVPHGTAAGREGLDALLATSALTDDLAVFFIADGVFQLLPGQKPDAVLARDYIATFKLLGLYDIEQCWVCAASLRERGLDPQTPFVVEATPLEADALRRELANYDVILRF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
What are the official names of this protein?
Protein TusC, tRNA 2-thiouridine synthesizing protein C.
What is the protein family that this protein belongs to?
Belongs to the DsrF/TusC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLOT1_RAT
Sequence: MFFTCGPNEAMVVSGFCRSPPVMVAGGRVFVLPCIQQIQRISLNTLTLNVKSEKVYTRHGVPISVTGIAQVKIQGQNKEMLAAACQMFLGKTEAEIAHIALETLEGHQRAIMAHMTVEEIYKDRQKFSEQVFKVASSDLVNMGISVVSYTLKDIHDDQDYLHSLGKARTAQVQKDARIGEAEAKRDAGIREAKAKQEKVSAQCLSEIEMAKAQRDYELKKATYDIEVNTRRAQADLAYQLQVAKTKQQIEEQRVQVQVVERAQQVAVQEQEIARREKELEARVRKPAEAERYRLERLAEAEKAQLIMQAEAEAESVRMRGEAEAFAVGARARAEAEQMAKKAEAFQMYQEAAQLDMLLEKLPQVAEEISGPLTSANKITLVSSGSGTMGAAKVTGEVLDILSRLPESVERLTGVSISQVNHNKPLRTA
What is the function of this protein?
May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles.
What are the official names of this protein?
Flotillin-1, Reggie-2, REG-2.
What is the protein family that this protein belongs to?
Belongs to the band 7/mec-2 family. Flotillin subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Endosome. Membrane, caveola; Peripheral membrane protein. Melanosome. Membrane raft. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Membrane-associated protein of caveola.
Protein: ACPS_SHESH
Sequence: MIVGLGTDIVEIERIEQKVPQAGDHEALAKCRLAKRVLTESEMAIFVASSKPGRYLAKRFAAKEAAAKALGTGIGRGVSFQHIEISNDANGAPQVNFSGGAAERLALLSGVRGHLSIADEKHYATATVILES
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIMT_AERPE
Sequence: MKSPVAGAVLDPSTPPPTTGTSWRWPGLRDADPYREARLRMVEQLRRSGLVTSRRVLEAMARVPRHLFVPPEYRGMAYEDRPLPIGHGQTISAPGVVGRMLQLLDPQPGEKVLDVGAGSGYQSALLAELVTPGGRVYAVERIPELAEYARENLEKTGYRGVVEVVVGDGSKGLPQHAPYHRIKVAAAAPKPPKPLVEQLAPGGRMVIPIGTPDLQILTIIEKTPDGRVRERRDIEVLFVPLIGEHGYREDWRKQYWQWWR
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins (By similarity).
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_NITHX
Sequence: MTRRNNGHSARFLVASASWFSHHSGMIREPSRDRPGRSPAVAPSFQHERALLKRGVWPVAGCDEVGRGPLAGPVVAAAVVLDPKRIPKGIDDSKRLTAARREELFEEITATASFAVAFASTARIDRDNILRASLWALARAVHALPDMPRHVFVDGRDRIEIACACEPVIGGDGIVLSIAAASIVAKVTRDRLMCKLAQDCPGYGFETHKGYGVPAHLEALGRLGPSPHHRSFFAPVVAARERHRAPPIGESASATETSAGISIEATI
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPX_SYNSC
Sequence: MAKFDAHLKCSFCGKSQDQVRKLIAGPGVYICDECIDLCNEILDEELVDGQGNSRHSHEPSRKAMPAARKSSKPAPTLASIPRPQDIKSFLDQQVVGQDAAKKVMSVAVYNHYKRLAWQGDGQGETEETATRLHKSNILLIGPTGCGKTLLAQTLAEMLDVPFAVADATTLTEAGYVGEDVENILLRLLQKAEMDVDQAQRGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKMLEGTVANVPPQGGRKHPYQDCIQIDTSQILFICGGAFVGLEDVVQKRMGRNAIGFMPSDGRGRSRANRDLQAAQVLRHLEPDDLVRYGLIPEFIGRMPVSAVLEPLDESALQSILTEPRDALVKQFRTLLSMDNVQLQFADDAIEAIAQEAHRRKTGARALRGIVEELMLDLMYDLPSQTSVKEFTVTRAMVEEHTGGKVLPLPGAEQQKTA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: NMU_RAT
Sequence: MSRAANRRPGLSAGQLAAATASPLLSLLLLLACCADACRGTPISPQRLPPEQELQLWNEIPEACASFLSVDSQPQASVALRKLCRVLMEIFQKPQEQTEKDNAKRFLFHYSKTQKLGNSNVVSSVVHPLLQLVPQLHERRMKRYKVNEYQGPVAPSGGFFLFRPRNGKRSTSFI
What is the function of this protein?
Does not function as a ligand for either NMUR1 or NMUR2.  Indirectly induces prolactin release from lactotroph cells in the pituitary gland, probably via the hypothalamic dopaminergic system.
What are the official names of this protein?
Neuromedin-U.
What is the protein family that this protein belongs to?
Belongs to the NmU family.
What are the subcellular locations of this protein?
[Neuromedin-U-23]: Secreted.
Protein: YAO2_SCHPO
Sequence: MSNLEFVYKYFNSLDVKELYDIYLLRTNVFVVEQKCAYPEVDEIDLKCGHLMLRNANGKLVAYARLIPEQQQTVRIGRVVVDPDERKNGYGRKLMLQALETSKQEFSSSKTFVLSSQEYAQPLYRSVGFKKCSDAYLEDGIPHVEMRLEL
What are the official names of this protein?
UPF0039 protein C11D3.02c.
What is the protein family that this protein belongs to?
Belongs to the UPF0039 (ElaA) family.
Protein: MTA1_THAGE
Sequence: MKTIDLFCGAGGLGEGFRQAGFSALYANDHETPALATYKENHPDAVCSTDSIETVDPKKIREDLGVAPGQVDVVMGGPPCQGFSTYGQRRDDDARNQLYVPYFGFVEEFRPKAFLIENVVGLLSMSGGAVLADMVARAEALGYAADVVTLDACEYGVPQHRRRVFIFGAADGQRIDPPQPSHVNGKRSGVVLNDQPSLFFDGPSIQPALTVRDAISDLPDEVLVPRDTQKPMEYPEPPKTEYQRLMRGNSTELTHHSAKRMLGIRRLRLAMLHPGDYGTKIEERLADGGLNDELIDLMMGGAGMRDAAECRTQDREKEAALREVLKGGHTTPAKVMEFLDSQGFANKYRRLRWDAPSHTVVAHMARDCSDFVHPGIDRFVSVREAARFQSFPDTYRFPGSQFRQFRQIGNAVPPLLGRAMAETIKVAIS
What is the function of this protein?
A methylase, recognizes the double-stranded sequence 5'-ACCGGT-3', methylates C-3 on both strands, and protects the DNA from cleavage by the AgeI endonuclease.
What are the official names of this protein?
Type II methyltransferase M.AgeI, M.AgeI, Cytosine-specific methyltransferase AgeI, Modification methylase AgeI.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
Protein: FOLD_CALS8
Sequence: MAQRIKEEVKSEIEKLKEKGIESTLAVVIVGNDPASRSYVNSKKRTCLELGINSVEYALDTTTTQEQLENLIEKLNQDPKINGILVQLPLPNGLDESRVCKKILPQKDVDGFHPMNVGMLATGIDFEYSIKPCTPFGVIELLKRENIEIKGKHAVVIGRSNIVGKPLALLLLRENATVTICHSYTRDLKDICKTADILVAAVGKPKFVTADMVKEGAVVIDVGINRDETTKKIVGDVDFETVRRVASYITPVPGGVGPMTVAMLMKNTLFATLLQNGLI
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.