PharMolix/UniProtQA huggingface dataset:
Protein: ATP23_NEOFI
Sequence: MSDSQPGSTSSTGGKSDSGYIPGDDTWTQWRNIFAILTGKMTDEGKEQFRIARDIRNEAADCKRCEDQRDYLLQYSPIIRFLSDNIRQLGGDLSSHNIYCRRCTSRKAGGFDPEYGILLCANEMKDQGHLEDTMAHEMVHAYDHLRFKVDWTDNLRHAACTEIRASSLSGECRWAREFFRRGQWKFTQQHQECVRRRAILSVRARPGCKDEAHAEKVVNEVWDSCFRDTRPFDEIYR
What is the function of this protein?
Has a dual role in the assembly of mitochondrial ATPase.  Acts as a protease that removes N-terminal residues of mitochondrial ATPase CF(0) subunit 6 at the intermembrane space side.  Also involved in the correct assembly of the membrane-embedded ATPase CF(0) particle, probably mediating association of subunit 6 with the subunit 9 ring (By similarity).
What are the official names of this protein?
Mitochondrial inner membrane protease atp23.
What is the protein family that this protein belongs to?
Belongs to the peptidase M76 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Note=Associates loosely with the inner membrane.
Protein: SPAT9_BOVIN
Sequence: MPIKPVGWICGQVLKNFSGRIEGIQKVIMDLIDEFKDEFPTILRLSQSNQKREPMQKPSKIRMAIALAKINRGTLIQGLNSISRSSKSVAKLLQPQLACRLLELRAISHRLLKEVNAPRQPLYNIQVRKGSLFEIISFPAKTALTSIMCASYAALIYLTVCVNAVLEKIMKIFQEEESIRQNREESENFRNAFSEPVLSEPLFPEGEIKAKPYRSLPEKPDSISDRPKLPANKLSNKIQVLHSVFDQSAEMNE
What is the function of this protein?
May play at role in testicular development/spermatogenesis and may be an important factor in male infertility.
What are the official names of this protein?
Spermatogenesis-associated protein 9.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: GET1_MALGO
Sequence: MYITNDEFRVFYVRIVRFSASSKLSSMKKELFETRQLMNMTSAQDEFSKWAKLRRRVDKLSSQVDEQNKSLASSQFVYSIMFKSFMFVLNSAIPFVLNWYYKRVPMFYLPPGDWFGPMGYLFSFPNAPAGAVSSTVWTTVCGRVLALVGEYARELFVKDAYLVAEPPMTTEKSSGDKETTSKLSTNKPAAMTGEKFDFGKEVKEADQPQGILKQRRANKSSD
What is the function of this protein?
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol (By similarity).
What are the official names of this protein?
Protein GET1, Guided entry of tail-anchored proteins 1.
What is the protein family that this protein belongs to?
Belongs to the WRB/GET1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MEND_SHELP
Sequence: MQIEKTAELNLLWGSLILEELARLEVQHVCMAPGSRSTPLTLAAAKQTKLKQHLHFDERGLGFLALGLAKASRAPVAIITTSGTAVANLYPAIVEAWLTQVPLIVLSGDRPPELLGCGANQAIVQPAIFADYAKQVNLPTPDMAIPPQALLTLLDESVANAKGPIHVNCMYREPLYPGSMSADFTHYLSPLGNWQHSALPYNQFADAQLVSAPTSDALARFVHGKGVIIAGTLAPEQQPEQLIELAQKLGWPLLTDAQSQLRQHGAAIGNIDQLLLQPKAKALLQEADTVLVFGGRLLSKRLISYLSEQKWKRYWQVLPQQTRLDPSHSAKQVWISPLAAFAQLPWPRSSEANWALQLIEANEQLATLFQQQIDDAEFGEAQVVRTIAGRGEQQLFIGNSLPVRLYDMYAPITPIAPRVFTNRGASGIDGLLATACGIAAHKASSTTLVIGDLSQLHDLNSLALAAKQQGTLVIVILNNDGGNIFNLLPVPDEKLRSGYYRLAHGLEFGYGAAMFGLPYNRVEDIVSFNEAYDDALAYPGASVIEVCVAQDQASEQIARLAAWIKQS
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: NEF_SIVS4
Sequence: MGGAISKKQYKRGGNLRERLLQARGETYGRLWEGLEEGYSQSLGASGKGLSSLSCEPQKYSEGQYMNTPWRNPATERAKLGYRQQNMDDVDDEDDDLIGVSVHPRVPLRAMTYKLAIDMSHFIKEKGGLEGIYYNERRHRILDMYLEKEEGIIPDWQNYTSGPGIRYPMHYGWLWKLVPVDVSDEAQEDETHCLVHPAQTYQWDDPWGEVLAWKFDPELAYSYKAFIKYPEEFGSKSGLSEEEVKRRLTARGLLKMADKKETS
What is the function of this protein?
Interferes with TCR signaling from the cell membrane.  Interacts with CD247/TCRZ (TCR zeta chain) and exert potent down-regulation of cell surface TCR/CD3 complexes.
What are the official names of this protein?
Protein Nef, 3'ORF, Negative factor, F-protein.
What is the protein family that this protein belongs to?
Belongs to the lentivirus primate group Nef protein family.
What are the subcellular locations of this protein?
Host cell membrane; Lipid-anchor; Cytoplasmic side. Note=Associates with the inner plasma membrane through its N-terminal domain.
Protein: DDL_STAAB
Sequence: MTKENICIVFGGKSAEHEVSILTAQNVLNAIDKDKYHVDIIYITNDGDWRKQNNITAEIKSTDELHLENGEALEISQLLKESSSGQPYDAVFPLLHGPNGEDGTIQGLFEVLDVPYVGNGVLSAASSMDKLVMKQLFEHRGLPQLPYISFLRSEYEKYEHNILKLVNDKLNYPVFVKPANLGSSVGISKCNNEAELKEGIKEAFQFDRKLVIEQGVNAREIEVAVLGNDYPEATWPGEVVKDVAFYDYKSKYKDGKVQLQIPADLDEDVQLTLRNMALEAFKATDCSGLVRADFFVTEDNQIYINETNAMPGFTAFSMYPKLWENMGLSYPELITKLIELAKERHQDKQKNKYKID
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDM12_MALGO
Sequence: MSIELDWTGLEKSFADSLCERLNAALADMDMPTFLGPTRVQAIELGSEGPDVQVIHIGHVWREFREAAVHASSASDKYNARATTPPRMPMRLRTFRQYDDNDLPTSVHGGADADSIASEHEESLSRWSDTESETGTCDSSSLWEEQTRLSDIPSLQMHLSVQWLTSTMRLSLTTSLKIAYNNDTIMSLPISLVVTGMELFAQAIVALDGVHRCVYLSLSEDSTEECAPDGLRAVHDARIRTRHQGQRILPFLALESKVGESAKHVLENVGKVERFVGDMLRQWLEDELVYPHFYTLYL
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.  The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 12, Mitochondrial inheritance component MDM12.
What is the protein family that this protein belongs to?
Belongs to the MDM12 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: RL2_ALIB4
Sequence: MAIKKFRPITPARRFMSVMDTSDITSKPTVRSLLVKVKASAGRNNNGRITSRHKEAGAKKLYRIIDFKRNKFGIEGTVATVEYDPYRNCRICLVSYLDGDKRYIIQPSGLKVGDKVQAAESGLDILPGNAMQLSNIPVGTMVHNIELKPGKGAQIARAAGGYAQIMGREDKYVILRLPSGEMRKILGVCMATVGVVGNEDYTNMVVGKAGRSRHLGIRPQTRGSAMNPIDHPHGGGEGKTNSGRHPVTPWGMPTKGYKTRKKKASDKLIISKRKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RS9_PSEFS
Sequence: MSATQNYGTGRRKTATARVFLRPGTGNISINNRTLDNFFGRETARMVVRQPLELTETVEKFDIYVTVIGGGVSGQAGAIRHGITRALMQYDETLRGALRKAGFVTRDAREVERKKVGLRKARKRPQYSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: GPDA_ORITB
Sequence: MKIAIIGAGAWGTAIAMLLARNNYRVTLYTRHSAHTQEINQLHTNKKYLPNIILPNIIKATSNFSDIVDHEIIIIVTPSDQVRATIENLKQHSISNNAIIGIASKGLDHNQSKLLSDVVKDYLANNPLFIIAGPNLANEVAQGLPCALTIAAIQKEVQFNISTLFHSTNVITSTTEDIITIQVASAFKNIIAIIAGIIIAKQYGQNCKASIITQGIKEIVAFARAAGSTNPDISQFGVIGDLILTSYAITSRNTKFGYDLGQHEYYTNLINNTNPNLIEGIKAAKILYPLTVKQNLNCHIIDCAYSILHNGSKISYAIECMLKKINHETK
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVC_METSB
Sequence: MRVYYDRDADINLIKSKKVAIIGYGSQGHAHALNLRDSGVMDVSVALREGSATAAKAAGEGLKVLSVADAAKWADVVMMLTPDELQGDIYSEHLAPNLKQGAALLFAHGLNIHFNLIEPRKDLDVAMVAPKGPGHTVRSEYKRGGGVPCLIAIAQDASGNAHDIALSYASAIGGGRAGIIETTFREECETDLFGEQVVLCGGLVELIRGGFETLVEAGYAPEMAYFECLHEVKLIVDLIYEGGIANMNYSISNTAEYGEYVTGPRIVTPETKAEMKRVLTDIQSGKFTRDWMLENKVNQTSFKATRAKAASHQIEEVGAKLRAMMPWIGANKLVDKAKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: SEC31_ASPTN
Sequence: MVRLREIPRTATFAWSPGADSPLIATGTRAGAVDVDFSNETCLELWDLGLSREDVSGELQPAAKIDTDSGFNDIAWTESDDNKRGVIAGALENGSLDLWDADKLLNGSSDSVISRSTKHSGAIKALQFNPKHSNLLATGGAKGELYISDLNNVANPYRLGTAARADDIECLDWNKKVAHILVTGSNAGFVTVWDVKSKKESLTLNNVGRKAVSAVAWDPEKPTRLVTATPLESDPMICVWDLRNSHAPERTLRGHESGVLSLSWCTQDPDLLLSSGKDNRTLCWNPQTGYAYGEFPVVTNWTFQTRWNPHNPNFFATASFDGRISIQTIQNTSTDTAKAIADQNQALDGEDFFAKAQSQPQVSSFSLPKAPKWLERPCGATFGFGGRVVSVGLTEKGSRTSTIKITPFEVDEAVGKSTETFENALKEGDLRSICETRATNAATEEEKADWKVIEALISENPRKSLVDYLGFQDKADEAADSLAKLGLGKDEDVNGEPAKESRGPGAKKHKRLQSMFDANPEGDSFLSDLAASKGAKTNNPFQIFNGSESEAEKGITRALLVGDFEKALDVALKEDRMSDAFMIAICGGQKCIEKAQEHYFSKQTDSPNYVRLLASIVGKNLWDVVHNADLSNWKEVMAALCTFAEEKEFADLCEALGDRLEEQVRSSDEKSARKDASFCFLAGSKLEKVVAIWIEELAENEQKAIETGANDTTFSIHVHALQSLIEKVTIFRQVSKFQDTEHTKDSDWKLGMLYDKYIEYADVVATHGRLQVAQKYLDLVPEKHPEAEIARNRIKLAMRQAAPQRTQTTAPATRATRTPMGRPMPQPSAYQPQSTFAPAAPAAPNTYAPPTAAPNPYAPAAPAAAAPAPPQPVNPLLPHRRMAVFLLLLRANNQSPATVTTYTTATNLPAWNDLPEGFMKPPTSRRATPATAAAPITSPFPNQSPPIGHGPPPPGAPPTQRTPSVPPPPKGTAPPPRMSSPLAGAPPMASMAPPPAAAPAPAPPANPYATLPQSPPMASSMAPPASIPRGPSPYNAPPTAPPPSNRYAPSPAAQAASPQLQTRAPVPPPPQAAASPYAPQPMAQPPAANPYAPSTPPMVAPPMQQGPPPPQAGGSRPSTANSQRKAAPPPPKYPPGDRSHIPAEAMPVFEILSADMQRVKSRAPSSFKAQVDDAERRLNILFDHLNNEDLLKPNTIADMAELARAIQARDYDTARAIHVDIMTNRMDECGQWMVGVKRLISMSRATP
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
What are the official names of this protein?
Protein transport protein sec31.
What is the protein family that this protein belongs to?
Belongs to the WD repeat SEC31 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PAKD_DICDI
Sequence: MSRLQPQQQQRGRSSSFKDNFQIQKPLQSLTPSEQQQQQQQQQQQQQQQQQQQQQQQQQNNANNNNNNNNNKFNNQYIQQMKNVENDIKKWIGEKCSSSLSDDFLEKDLMESLCTGTILCVLINMIKQGTIQKIHLQPNYLQRVENIRNYLRACWLFGLHSKYFFPSSYLLSMTIENNDNSNSSKTTTNNNNNNNNNNNNNNNNNNNNNNNNNNRAIITSPNKNGGVNTMIVNLEYKEKIMINLTELCKISLKIKNFGSFLQLSSSSSSTPPPPINNNNNNNNNNNNNNNNNNDLLISNNSSNISSPNSFSDSPMGFSSSINSSSNNSNLNTPNNYNNTNNNNNNNNNNNNNNNNNINNLTPQMIISSPTSTSSTPPLPPCANNINNNNLKKRTKIPKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKIIIKRDCKKVYRKRKSSNCDNDDNGSNSDSDSSDSSDSSDSDSDSLLSSDGTPIILSQSSNPESVSFKSFIKEILHLKNIISKQDKTITSQKQTIETLEKDLEFQKQLTKKLLSSPIDLSNFIETSSDPNGAIPVSIQAFTRQIQQIQTLQQQNLSLETELSKTNEHLSTNIRKNSKLENEVLSIETELLNLRMKYANTLSSSNSNGNNNSNNNSLGCNNSINGSSSGGGGNNSSTSKGTLSRTISQPFPLRKSISHSNIITSPVNSHQQQQQQNQLSQSQTTSPKNTSASYNNGILSKSSIVSNTNTNSTYKFGSSTGILKVSATLQQKQQQQQQQQNQQQQQNQQQQQQNQQQQNQQQQNQQKQNQQQQNQQQQQQQQQQQQQNQQQQQQQQQQQQQQQQQQNQQQQQNNQLSQSQQLQQQQNQQINNLIDSPLIISNSSNQQIESESIESDSDYDKDMVDFGKKIVSALISSSNHVEMSEIYKMNDILTNETSRRQICIVLEEETKINQLKLPMNENSFEVTLYLVNTILQCIHEAPSKDYFSLKLIMESSRILNRKKVNGSCEFIQEFIKDHPTWKDIKFWEEQYWDELIIKHQQFSGSGSSSSSNTGGSIVTTMTTTTTVTSAITSSSSTTSDDFDVDYTELVNTLLISYVYNLASWGLSKSDVKEFTISMSKKSFLKSNELEKLIEQVTSTVELSFTSDHNVCKGPHSFVLKSFRIISECNYCRQYIWGVRGIVAREAFECVGCKYKTHKKCLKEASEKTFCSSPNVGAPFNVKHEMHVGLAIQGLPSGWRTLLLQSGFQDYEIQQHQEDVLDVLEFHHVYNEKQQNSIKLLTNNSNNNNNNNNSNNNLQQQQQQNQQLKQKLNITNNQQNNTIININITSPSISVNNNTYNNNNNNNNNNEINPSSPNNNNNYYDSLLEIEEPSFTLKDLVSLENPIDLYKVREVVGGGSTGKVYVGENSITGEKVAIKKMKVDNNNIKNIINEISTMKNSKHKNVIKYVSSHLVINHIWLIMEYMSYGSLTDLISNCINIQCNGNNQQQQQQQQQQQTYFIESHIAYICQQVLQGMDYIHKGHRTHRDIKSDNILLGKDGSVKIADFGFVANLTRKKLQRNSVVGTPYFMAPELIRGNQYNHKVDIWSLGILARELSEGEPPYAKYPPVRALFLLTLEGVPDFKEPNKWSSDFIEFVNLCLNLDDKRRPDAHYLLRHPFLKKACSSREFADKVEEIYNTRKNQFSDINFNF
What are the official names of this protein?
Serine/threonine-protein kinase pakD.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
Protein: TSX_RAT
Sequence: MSEEQEPKTSEAEYGTMDFPEFENEEEWLFKVLGIKPRPSSDLDDADKQEDEPLGHTEFLRLQDILQEDKVSSTNDSDTCQAGYTEENDEASHSDSDIDDNVNVIIGDIKANSSMYMEMFTNMNSQADQDLKLTESDNAMYPTD
What is the function of this protein?
May have an RNA/DNA binding role.
What are the official names of this protein?
Testis-specific protein TSX.
Protein: YBEY_COREF
Sequence: MSIEVFNESGYDGVNEEMLIDVLSFALGEMDIHPDAEASIHIVDSDTIAELHVKWLDLEGPTDVMSFPMDELTPGYSRPDGGAPGPAMLGDIVLCPEFAEKQATKAGHDLSHELALLTVHGCLHLLGYDHVEPAQEREMFALQNELLADWYDDVDRRGVVYQPKPTGPGAFPTAADRLELDQTMIAEEQGEPGESGASAR
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_LOCMI
Sequence: MNKPLRIKHPMIKIINNSLNDLPAPTNISMWWNLGSLLGMCLMIQIVTGLFLTMHYTPNIEMAFSSVVHICRDVNNGWLIRTLHANGASMFFICMYLHVGRGIYYGSYMYMNTWMTGTIILFLVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDIVQWVWGGFAVDNATLNRFYTFHFVLPFIVMAMVMIHLFFLHQTGSNNPIGLNSNIDKIPFHPYFTYKDMITFIILMMILIMLCLIDPYMLGDPDNFVPANPLVTPIHIQPEWYFLFAYAILRSIPNKLGGVIALVMSISILMIMPFYNKTKFRGNQFYPMNQIMFWIMVIVICLLTWIGKRPVEEPYIMTGQILTIIYFSYFLFNVHIAKMWDTLIKT
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: REX_STRPB
Sequence: MVIDKSIPKATAKRLSLYYRIFKRFHADQVEKASSKQIADAMGIDSATVRRDFSYFGELGRRGFGYDVTKLMNFFADLLNDHSTTNVILVGCGNIGRALLHYRFHDRNKMQIAMGFDTDDNALVGTKTADNIPVHGISSVKERIANTDIETAILTVPSIHAQEVTDQLIEVGIKGILSFAPVHLQVPKGVIVQSVDLTSELQTLLYFMNQNHLD
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_DESVM
Sequence: MSTIVSVWAREILDSRGNPTVEVEVSLESGHTGRAAVPSGASTGSREALEMRDGDKGRYKGKGVEKAVDNVMGEIAEAIVGLDSLRQVQVDNTLLDLDGTDNKSRLGANAMLGVSLATARAASSFLGLPLYQYLGGVNAKVLPVPLMNIINGGAHAPNNLDIQEFMIMPIGAATFRDALRMGAETFHTLKALLAADGHVTSVGDEGGFAPNLKNHDEAFRYIMKAIEEAGYIPGAEIALAIDAAASEFHKDGKYVLAGEGKNLSNSEMVEWLGEFTTRYPLISIEDGLAEADWDGWRELTYKLGDTIQLVGDDIFVTNPDILAEGIDEGVANSILIKLNQIGTLTETLDTIEMAKQAAYTTVISHRSGETEDHFISDLAVGLNAGQIKTGSLCRSDRLAKYNQLLRIEEDLDDTGIYFGPMMSSHFGFEEEGEE
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: FTHS_TREDE
Sequence: MKTDIEIAREAKLKKIAEIADGLGIHDDNVIPYGKYIAKVPYSVIDDAKVKKNNLILVTAITPTKAGIGKTTVSIGLALGLNKIGKKAVAALREPSLGPCFGMKGGAAGGGYAQVLPMEDINLHFTGDFHAITSAHNMISALFDNYIFRAQGTPKAIKTVLWKRVLDVNDRNLRQVVTGLGEGNGVVMESGFDITPASEIMAIFCLAKDIEDLRRRIENIILGYDTENNAVKVKDLGIAGSIVVLLKNAINPNLVQTTENTPAFIHGGPFANIAHGCNSVIATKTALTYGEYVITEAGFAADLGAEKFFDIKCRKAGLNPKLTIIAATTGGLKMHGDVPEKEISKPNAEALKKGLANLDKHIENMKKFGQTVVVALNRYGYDIDSELELVRKHCEAQGVGFAVNNAFVEGGKGAVELAELVVKTIETNPSKPLKFVYEDKDSIKTKIGKICKEIYGAADVTYSGAADKMIKKIEEAGMADFPVCVAKTQYSFSSDPKLYGVPTGFEMNVRDIVLNSGSEMIVAIMGDMMRMPGLPKDPQAVRIDLVNGNVEGLS
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: PYRF_LISMH
Sequence: MNKPIIALDFQTYEEVEQFLAKFSGEALSVKVGMELFYSNGPIIVEKIKQQNHEIFLDLKLHDIPNTVKSAMVGLAKLGVDMVNVHAAGGKNMMEAALEGLEIGSGSGKRPKIIAVTQLTSTSEASMQSEQLIKTSLLESVLHYSALTNQAGLNGVVCSALEAEAIKQQNGADFLRVTPGIRLASDAADDQIRVVTPEKARLIGSTDIVVGRSITRANDPVAAYNQVLKEWNV
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: RL6_SYNSC
Sequence: MSRIGKNPVPVPEKVTVSLDGLTVKVKGPKGELERTLPEGVSVSVSQDNNTIVVSPTSTKRISRERHGLSRTLVANMIEGVSNGYSKALEIVGVGSRAQVKGKTLVVSAGYSHPVEMEAPEGITFKVENNTRVIVSGIDKELVGNEAAKVRAIRPPEPYKGKGIKYEGERILRKAGKSGKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: SELU_NITEC
Sequence: MNNPNIDSDELTALFTADTPLIDVRAPLEFILGSLPGSVNLPILNNEERALVGTTYKQQGSEAAVMLGHEMISGQAKQDRLQQWLDFIRQHPRTVLYCFRGGKRSQITQQWLKDAGVDRPLIIGGYKQARQFLINTIDRFSENHTLLVITGPTGSGKTQLIQEIRNSYPVLDIEALARHRGSAFGGMSLPQPTQIDFENQLAVNLLKLKQNYLFDPVVVEDESRHTGRVYLPASFFEHMRSSEIIWVDEPLNTRVDNIFGDYIVATPIGQAQQARRNTQPLSSATEIQEILCQQALLLFDKYASALQAISKKLGGVRFQEVSQDLENARSSFVNRNEIQSNKTWIEKLVRYYYDPLYLGSLQRRQVNPCFKGSRQAAIDYLRARKQHA
What is the function of this protein?
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA).  Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
What are the official names of this protein?
tRNA 2-selenouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the SelU family.
Protein: NCAM2_MOUSE
Sequence: MSLLLSFYLLGLLVRSGQALLQVTISLSKVELSVGESKFFTCTAIGEPESIDWYNPQGEKIISTQRVMLQKEGVRSRLTIYNANIEDAGIYRCQATDAKGQTQEATVVLEIYQKLTFREVVSPQEFKQGEDAEVVCRVSSSPAPAVSWLYHNEEVTTIPDNRFAVLANNNLQILNINKSDEGIYRCEGRVEARGEIDFRDIIVIVNVPPAIMMPQKSFNATAERGEEMTLTCKASGSPDPTISWFRNGKLIEENEKYILKGSNTELTVRNIINKDGGSYVCKATNKAGEDQKQAFLQVFVQPHILQLKNETTSENGHVTLVCEAEGEPVPEITWKRAIDGVMFSEGDKSPDGRIEVKGQHGRSSLHIRDVKLSDSGRYDCEAASRIGGHQRSMHLDIEYAPKFVSNQTMYYSWEGNPINISCDVTANPPASIHWRREKLLLPAKNTTHLKTHSVGRKMILEIAPTSDNDFGRYNCTATNRIGTRFQEYILELADVPSSPHGVKIIELSQTTAKISFNKPESHGGVPIHHYQVDVKEVASETWKIVRSHGVQTMVVLSSLEPNTTYEIRVAAVNGKGQGDYSKIEIFQTLPVREPSPPSIHGQPSSGKSFKISITKQDDGGAPILEYIVKYRSKDKEDQWLEKKVQGNKDHIILEHLQWTMGYEVQITAANRLGYSEPTVYEFSMPPKPNIIKDTLFNGLGLGAIIGLGVAALLLILVVTDVSCFFIRQCGLLMCITRRMCGKKSGSSGKSKELEEGKAAYLKDGSKEPIVEMRTEDERITNHEDGSPVNEPNETTPLTEPEKLPLKEENGKEVLNAETIEIKVSNDIIQSKEDDIKA
What is the function of this protein?
May play important roles in selective fasciculation and zone-to-zone projection of the primary olfactory axons.
What are the official names of this protein?
Neural cell adhesion molecule 2, N-CAM-2, NCAM-2, Neural cell adhesion molecule RB-8, R4B12.
What are the subcellular locations of this protein?
[Isoform Long]: Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform Short]: Cell membrane; Lipid-anchor, GPI-anchor.
Protein: TRPA_DESPS
Sequence: MTLEKILREKKKDKDILLMTHIVLGYPSFAANREVIEQMVKNGVDCIEMQIPFSEPMADGPVILKANQESLARGTRVAQCFDFAREMTRKHQIPFLFMTYYNIVFKYGEERFFQDAKEAGIKGLIVPDLPPEMGEDYFAYAEQYQLAPIIIYAPTSTPERMKTLAGSATGFIYCAARRGVTGNNSALDENFDNYLSNCRAATTLPLAVGFGIKSKADVQALIGKADMAVIGSQTIRLVDENGPKAVGPFVASLR
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: REX_LACLA
Sequence: MTDHKPSKSLPKATAKRLPQYYRLFKSLVEENVTRTNSQLISEKIGVDAATIRRDFSLFGELGRRGYGYETKVLRDFFGELLGQDQETHIALIGVGNLGRALLHYQFQDRNKMRITQAYDISGNPLVGTQTDDGIPIYNISDLEKNVKKSDIKTAILSVRKENAQEVVDTLVKAGIKVSLNFAPIRLKVPSDVVVQSIDLTKELQTLLFFMNDNKQ
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.