PharMolix/UniProtQA huggingface dataset:
Protein: GCSP_BURP1
Sequence: MKLEHPDRLMNRTPLSLAALETHDAFAERHIGPDAASQQAMLDTLGFATRAALIDAVIPASIRRAETLPLGPFAQPKSEAEALAALRALADKNQVFRSYIGQGYYDTHTPAVILRNVLENPAWYTAYTPYQPEISQGRLEALLNFQQMVADLTGLEISNASLLDEATAAAEAMTLLQRVGKPQSNVFYVADDVLPQTLEVIKTRAKPIGIEVKSGPAADAAAANAFGVLLQYPGANGDVRDYRALADAIHAAGGHVVVAADILALTVLMPPGEWGADVAVGNTQRFGVPMGFGGPHAAYMAVRDEFKRQMPGRLVGVTVDAQGKPALRLALQTREQHIRREKATSNVCTAQALLAIMASMYAVYHGPRGLKTIALRVNRIAALLAAGIRHLGYATVNDTFFDTLTIDTGARTAQLHAFAQAKRINLRRAGDTRVGVSVDETTTRADLADLLTIFAQAAGATAPDIDALDAGLLPAPALPPSLERTSAYLTHHVFNRHHSETEMLRYLRSLSDKDLALDRSMIPLGSCTMKLNATSEMLPVTWPEFGRIHPFAPAEQTVGYREMIDQLEQMLVAATGYAAVSLQPNAGSQGEYAGLLIIHAYHESRGESHRDVCLIPASAHGTNPASAHMAGMKVVVVACDAQGNVDIADLKAKADAHSHDLAAIMITYPSTHGVFEQNVREICEIVHAHGGQVYVDGANMNAMVGLTAPGQFGGDVSHLNLHKTFCIPHGGGGPGVGPVAVGPHLAKFLPNQRSTGYARGEDGIGAVSAAPYGSASILPISWMYIAMMGAKNLTAATETAILNANYIAKRLAPHYPVLYSGPGGLVAHECILDLRPIKDSSGITVDDVAKRLMDYGFHAPTMSFPVPGTLMVEPTESESQEELDRFIAAMIAIRDEIRAVEEGRADREDNPLRHAPHTAAVVTANEWPHAYSREQAAFPVASLVANKYWPPVGRADNAYGDRNLFCSCVPVSDYA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: TPIS_BOMMO
Sequence: MGRKFVVGGNWKMNGDKNQINEIVNNLKKGPLDPNVEVIVGVPAIYLSYVKTIIPDNVEVAAQNCWKSPKGAFTGEISPAMIKDVGVNWVILGHSERRTIFGEKDELVAEKVAHALESGLKVIACIGETLEERESGKTEEVVFRQLKALVSAIGDKWENIVLAYEPVWAIGTGKTATPQQAQDVHHALRNWLSANVSGSVSDAVRIQYGGSVTAANAKELASCKDIDGFLVGGASLKPEFVEIVNANQ
What are the official names of this protein?
Triosephosphate isomerase, TIM, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
Protein: PSB_METMS
Sequence: MDNDKHLKGTTTVGIVCSDGVVLATEKRATMGNFIASKTAKKIYQIDDLVGMTTAGSVGDAQQLVRMISVESKLYKMRRQESITIKGLTTLLSNILGGQRYFPLMVQLLVGGVDKNGPAIFSLDAMGGNIEETKAVATGSGSPMAYGVLEDRYHEGINVDEGMELAVRALYNAMKRDSASGNGIDVVKITADGYKRIETGEVDKILENLK
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta, 20S proteasome beta subunit, Proteasome core protein PsmB.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCAKD_BOVIN
Sequence: MFLVGLTGGIASGKSSVIQVFQQLGCAVIDVDIIARHIVQPGYPAHRRIVEAFGTEVLLENGDIDRKVLGDLIFNQPDRRHLLNSITHPEICKEMMKETFKYFLRGYRYVILDIPLLFETKKLLKYMKHTVVVYCDRDTQLARLMRRNNLSREDAEARIKAQLPLKDKARMARHVLDNSGEWSVTKRQVVLLHAELEHSLEYLPLRLGVLTGLAGIVGLLYLLTHYLLPSP
What are the official names of this protein?
Dephospho-CoA kinase domain-containing protein.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
Protein: PBP2A_BACSU
Sequence: MRRNKPKKQNHKEKKKSLPIRLNILFLAAFVIFTWIIVELGIKQIVQGDDYKNQANKQEQSEVSSAVPRGKIYDRNFNAIVTNKALNAITYTRSKSTTQEQRLKIAKKLSDMIKVDTKKVTERDKKDYWILTRPKEAKKLISSKERQQVEDKKISDDDLYQLQLKRITDKQLNELTDKDMQILAIKRQMDSGYALTPQYIKNEDVSAKEMAVVSEHLDELPGVDVTSDWEREYPYKNLLRSVLGSVSSSNEGLPSNLLDHYLSLGYSRNDRVGKSYLEYQYESLLQGQKAKVENITDSKGNVTGTKTVSEGKAGKDLVLTIDIDLQKSVEKIIEKKLKAAKARPSTELLDRAFVVMMDPRNGEVLTMAGKQIKRENGAYKFDDYALGAMTSSYAMGSAVKGATVLTGLQTGAINLNTVFKDEPLYIGQDKRGKKSWQNLGPVGIQTALEKSSNVFMFKTAIAVGKGEYKPHQALPLDTSAFDTFRNYFSQFGLGVKTGIDLPNEMTGYKGTSRLSGFLLDFAIGQYDTYTPLELAQYVSTIANGGYRMKPQLVKEVRDSNAKKGIGAVVDSVQPEVLNKVDMKSSYIEEVQAGFRRVATKGTAAGQLASASYKPAAKTGTAQSFYDGPDKSKTGTDTYNTTLVAYAPADNPEIAISVVVPWTYIDYNQRYSITNEIGREVMDKYFELKSKQDKEGTQQKNKDKIEENAENTTSSDN
What is the function of this protein?
Involved in the synthesis of peptidoglycan associated with cell wall elongation, especially following spore germination (PubMed:9139922).  Has a partially redundant function with PBP 1 (ponA) or PBP 4 (pbpD) during spore outgrowth (PubMed:9851991).  Plays a redundant role with PbpH in determining the rod shape of the cell during vegetative growth and spore outgrowth (PubMed:12896990).
What are the official names of this protein?
Penicillin-binding protein 2A, PBP-2B.
What is the protein family that this protein belongs to?
Belongs to the transpeptidase family.
What are the subcellular locations of this protein?
Cell membrane. Forespore inner membrane; Single-pass membrane protein.
Protein: ADA2B_HUMAN
Sequence: MDHQDPYSVQATAAIAAAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADILVATLIIPFSLANELLGYWYFRRTWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEYNSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQGPQPRGRPQCKLNQEAWYILASSIGSFFAPCLIMILVYLRIYLIAKRSNRRGPRAKGGPGQGESKQPRPDHGGALASAKLPALASVASAREVNGHSKSTGEKEEGETPEDTGTRALPPSWAALPNSGQGQKEGVCGASPEDEAEEEEEEEEEEEECEPQAVPVSPASACSPPLQQPQGSRVLATLRGQVLLGRGVGAIGGQWWRRRAQLTREKRFTFVLAVVIGVFVLCWFPFFFSYSLGAICPKHCKVPHGLFQFFFWIGYCNSSLNPVIYTIFNQDFRRAFRRILCRPWTQTAW
What is the function of this protein?
Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.  The rank order of potency for agonists of this receptor is clonidine > norepinephrine > epinephrine = oxymetazoline > dopamine > p-tyramine = phenylephrine > serotonin > p-synephrine / p-octopamine.  For antagonists, the rank order is yohimbine > chlorpromazine > phentolamine > mianserine > spiperone > prazosin > alprenolol > propanolol > pindolol.
What are the official names of this protein?
Alpha-2B adrenergic receptor, Alpha-2 adrenergic receptor subtype C2, Alpha-2B adrenoreceptor, Alpha-2B adrenoceptor, Alpha-2BAR.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA2B sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Interaction with RAB26, GGA1, GGA2 and GGA3 mediates transport from the Golgi to the cell membrane.
Protein: HIS1_ALISL
Sequence: MSAQRLRIAIQKKGRLSKECQELFKRCGMKFNISGERLVVHSENMPIDLLLVRDDDIPSLIMDGVVDLGVIGENELEEVRLERKALGEPSAFTTLRRLDFGGCRLSIAIDKDAVYNGPQDLAGKRIATTYSQLLKSFMDEKNIPFSTCILNGSVEVAPRAGLSDAIADLVSTGATLEANGLKEAEVIFRSKATLIQREGEFDADKAALIDKLLTRMQGCIQAKESKYIMLHAPTDKLEAIKSLLPGAEDPTVLPLSSDGAKVAVHLVSTENLFWETMEQLKALGASSILVLPIEKMME
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LGT_STAAR
Sequence: MGGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYAENPGEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGPVSRAFLEQLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTRKVK
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HIP14_ARATH
Sequence: MTAKNAVLQLSIHEERTRKKALVTVSRFSGVTSITMDKSGKMTIVGEVDVPAVVMKLRKLCNTEIVSVDDVKPPVKKPEPEKPAESIAYPVPMNYAYQFNPAYANSYYHQPYGNCRVVDEPNCVIM
What is the function of this protein?
Probable heavy-metal-binding protein.
What are the official names of this protein?
Heavy metal-associated isoprenylated plant protein 14, AtHIP14.
What is the protein family that this protein belongs to?
Belongs to the HIPP family.
Protein: RECO_ACISJ
Sequence: MAARRIADEPAYVLHSYDWSESSLILETFTRHYGRVALVAKGAKKPTSNFRPVLLPLQPLRVTYTLGGEGHGEIHALKGAEWAGGHVMPTGDALLSGLYLNELLLRLLAREDTHAPLFDTYAGVVRVLATVDHEGEHGDALEPVLRSFELLLLREIGLLPGLDAETSTLAPLHAAARYALVPEAGLRPAVPADRAALSGGQWLALQGALDEPARYTATLRAIATAEAPVAADLKTQLRALLQYHCGSPLLRTRQLMMDLQKL
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: RPC3_CANGA
Sequence: MDILSDIKASVKGAPAPQQNPAAIKSENGNVDVSVSNEIHQQTAASTEELMSVSSLEQRTLHAEKFLYTEVIKSYLGERASTVISLLISLGRLTVREIYEKLNFTMSIDSIRRTLVSLTQLRCVRYLEEPKRGSAKYNTYYYYNKDGVYLLLYSGLIINDISSRFSEQKRPIVAEIIQNILSLGSLSLNDYLENVTYNIPKHEMSGLFVELCEMGFLVRLTKFDYTPIKDLWNLLYEKEYNQLPRNSTQSDLKKRTEAKNKAKTEFHNLMEASTDLSKLIKLDPSTSLRTVIPTATLTINIKRFLKSRRSLQLTNYARSRVGPVSAQLYKLALKLTENKAPYFNDILSETGLLQDLDELTAMSDEMELLEEKSPGVTFTANDILKIVPKNYKIENSLVYEKKSGKRSQNQEKSANTKRLKTEDGFVIPSLPTDNNHSNEKEIDDAEVEDGINEGDEMDADSVSIINSHLKILASSPVPFLKETQPNVYYIPYSNLIPELKSSIYDHIIVSTLGPPSLRIRRCIKENKLVSEKVINGTALMKEKDIRTTIGSLIKYNAVEIQEVPRTVDRSASRAVFLFRCNESHSYNFMKQNLAWNLANLLYKKEKIEDENKTLLMKANRDDVKGKERELLLPSELNQLKMVNERELNIFTRSFRLMSLWEVFEFF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase III subunit RPC3, RNA polymerase III subunit C3.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNY_STRA3
Sequence: MFNIILAMVCALIGLIIGYVAISMKMKSSKEAAELTLLNAEQDAVDLRGKAEIEAEHIRKAAERESKAHQKELLLEAKEEARKYREEIEKEFKSDRQELKQMEARLTDRASSLDRKDENLSNKEKMLDSKEQSLTDKSRHINEREQEIATLETKKVEELSRIAELSQEEAKDIILADTEKDLAHDIATRIKEAEREVKDRSNKIAKDLLAQAMQRLAGEYVTEQTITTVHLPDDNMKGRIIGREGRNIRTLESLTGIDVIIDDTPEVVVLSGFDPIRREIARMTLESLIQDGRIHPARIEELVEKNRLEMDQRIREYGEAAAYEIGAPNLHPDLIKIMGRLQFRTSYGQNVLRHSVEVGKLAGILAGELGENVDLARRAGFLHDMGKAIDREVEGSHVEIGMEFARKYKEHPIVVNTIASHHGDVEPDSVIAVIVAAADALSSARPGARNESMENYIKRLRDLEEIANGFEGVQNAFALQAGREIRIMVQPGKVSDDQVVIMSHKVREKIEQNLDYPGNIKVTVIREMRAVDFAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RAB8A_RAT
Sequence: MAKTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVNDKRQVSKERGEKLALDYGIKFMETSAKANINVENAFFTLARDIKAKMDKKLEGNSPQGSSHGVKITVEQQKRTSFFRCSLL
What is the function of this protein?
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes.  Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion.  That Rab is involved in polarized vesicular trafficking and neurotransmitter release.  Together with RAB11A, RAB3IP, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis (By similarity).  Regulates the compacted morphology of the Golgi (By similarity).  Together with MYO5B and RAB11A participates in epithelial cell polarization (By similarity).  Also involved in membrane trafficking to the cilium and ciliogenesis (By similarity).  Together with MICALL2, may also regulate adherens junction assembly (By similarity).  May play a role in insulin-induced transport to the plasma membrane of the glucose transporter GLUT4 and therefore play a role in glucose homeostasis (PubMed:21041651).  Involved in autophagy (By similarity).
What are the official names of this protein?
Ras-related protein Rab-8A.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus. Recycling endosome membrane. Cell projection, cilium. Cytoplasmic vesicle, phagosome membrane; Lipid- anchor; Cytoplasmic side. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body. Midbody. Cytoplasm. Note=Colocalizes with OPTN at the Golgi complex and in vesicular structures close to the plasma membrane. In the GDP-bound form, present in the perinuclear region. Shows a polarized distribution to distal regions of cell protrusions in the GTP-bound form. Colocalizes with PARD3, PRKCI, EXOC5, OCLN, PODXL and RAB11A in apical membrane initiation sites (AMIS) during the generation of apical surface and lumenogenesis. Localizes to tubular recycling endosome. Recruited to phagosomes containing S.aureus or Mycobacterium (By similarity). Non-phosphorylated RAB8A predominantly localizes to the cytoplasm whereas phosphorylated RAB8A localizes to the membrane (By similarity).
Protein: PRS4_YEAST
Sequence: MGQGVSSGQDKKKKKGSNQKPKYEPPVQSKFGRKKRKGGPATAEKLPNIYPSTRCKLKLLRMERIKDHLLLEEEFVSNSEILKPFEKKQEEEKKQLEEIRGNPLSIGTLEEIIDDDHAIVTSPTMPDYYVSILSFVDKELLEPGCSVLLHHKTMSIVGVLQDDADPMVSVMKMDKSPTESYSDIGGLESQIQEIKESVELPLTHPELYEEMGIKPPKGVILYGAPGTGKTLLAKAVANQTSATFLRIVGSELIQKYLGDGPRLCRQIFKVAGENAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDDRGDVKVIMATNKIETLDPALIRPGRIDRKILFENPDLSTKKKILGIHTSKMNLSEDVNLETLVTTKDDLSGADIQAMCTEAGLLALRERRMQVTAEDFKQAKERVMKNKVEENLEGLYL
What is the function of this protein?
The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins.  The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity).  Has ATPase activity.
What are the official names of this protein?
26S proteasome regulatory subunit 4 homolog, Tat-binding homolog 5.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PX24C_DICDI
Sequence: MSNSKPLSLTDAVTTWYMKKLKSKPIQTKALTSATLSFISSVVAQKFIEKKKINWNAVVKFTVWGLISSPLVHYWHIILDRLFKNIKDKYQSWGKLIVDQLVFAPFINIAFYSVLAILDGKPKSILFKLYFDLFPTLKASWKVWPLAQLINFRFVPSHLRVLFGNLVGFCWGIYLSILATKKRN
What are the official names of this protein?
PXMP2/4 family protein 3.
What is the protein family that this protein belongs to?
Belongs to the peroxisomal membrane protein PXMP2/4 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y295_UREPA
Sequence: MPRKHLIASGINKKQQQQAKIWMKCAKEIKAAAKMGGPNPEANSRLKVAIERALNNNLSRDSIERNINGASKDIDNLKELTYEGYGPNGLAIIVRALTDNEQRTISAIRGYFSKLQGQIAKPNSVSMLFNECGQLLINKETKSLDEWFEILIDQSIIDINEDDKIIEILVKPEDFSTVKLILEKNNADIKSAEIKLIPNDFISLDEYARERLVRFVNACENDDDISWVITNYEEEL
What are the official names of this protein?
Probable transcriptional regulatory protein UU295.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STR9_ARATH
Sequence: MAGIISPSPTALYFTSNVGGRRLKAVSWAGKSVSGNVIRRRSLRIAAELKFVNAEEAKQLIAEEGYSVVDVRDKTQFERAHIKSCSHIPLFIYNEDNDIGTIIKRTVHNNFSGLFFGLPFTKVNPEFLKSVRNEFSQDSKLLLVCQEGLRSAAAASRLEEAGYENIACVTSGLQSVKPGTFESVGSTELQNAGKAGLITIQGKISAVLGTVLVCAYLFIQFFPDQAEKLFPPTS
What are the official names of this protein?
Rhodanese-like domain-containing protein 9, chloroplastic, Sulfurtransferase 9, AtStr9.
What are the subcellular locations of this protein?
Plastid, chloroplast. Membrane; Single-pass membrane protein.
Protein: CH60_STRT1
Sequence: MAKDIKFSSDARAAMVRGVDTLADTVKVTLGPKGRNVVLEKAFGSPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREGLKNVTAGANPIGIRRGIEAAVAAAVEELKVIAQPVANKEAIAQVAAVSSRSEKVGEYISEAMERVGNDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDNEKMVADLENPYILVTDKKISNIQDILPLLEEVLKTSRPLLIIADDVAGEALPTLVLNKIRGTFNVVAVKAPGFGDRRKAMLEDIAVLTGATVITEDLGLELKDATMESLGQASKVTVDKDSTVIVEGAGSAEAIANRVNLIKSQLETTTSEFDREKLQERLAKLSGGVAVIKVGAATETALKEMKLRIEDALNATRAAVEEGIVAGGGTALVNVIAKVAELDLEGDDATGRNIVLRALEEPVRQIAYNAGYEGSVIIDKLKNSPVGTGFNAANGEWVDMVESGIIDPVKVTRSALQNAASVASLILTTEAVVADKPEQKAPAAPATDPGMMGY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LUXS_ACTP2
Sequence: MPLLDSFKVDHTRMNAPAVRVAKTMTTPKGDTITVFDLRFCRPNIDILPVRGIHTMEHLFAGFMRDHLNSESVEIIDISPMGCRTGFYMSLIGAPSEADVVSAWTKSMEDALNKVPDVSKIPELNEYQCGSYKEHSLEEAHQIARDVLAKGIGVNRNEDLALDEKLLNP
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: THIC_CLOBL
Sequence: MNYTTQMDAAKKGIVTKEMEIVAKKENMNVKDLMELVSKGKVAIPANKNHKSLDPEGIGQGLRTKINVNLGISKDCYNIDMELEKVQKAIDMKAEAIMDLSCFGKTEEFRKRLIDMSPAIIGTVPIYDAVGFYDKELKDITSEEFLKVAEKHAENGADFLTIHVGMNRKTAATFKKNPRRMNIVSRGGSLLYAWMELNNKENPFYEGFNKLLDICEKYDVTLSLGDACRPGCIEDSTDASQIEELIALGELTKRAWERNVQVIIEGPGHMTLDEIETNMKIEKKLCHGAPFYVLGPIVTDIAPGYDHITSAIGGAIAATHGADFLCYVTPAEHLRLPNLDDMKEGIIATKIAAHAADLAKGVKGARDWDNAMAKARRDLDWERMFELSIDEEKARRYREESKAKSKDSCTMCGKMCAVRNMNRVTEGKDLNMLRDDD
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: HYPA_PARDP
Sequence: MHEMSLCEGIRGIVEDQARRHGFSRVTRMRLEIGRFAGVEKAALSFAFDVVMRGSPAEGAVLEMIDLPGRAMCFDCAEQVELDDRLSPCPLCGGGRLMPETGDEMRIRDMEVI
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: PHAM_PHAVU
Sequence: MASSNLLSLALFLVLLTHANSASQTFFSFDRFNETNLILQGDASVSSSGQLRLTNVNSNGEPTVGSLGRAFYSAPIQIWDYTTGNVASFDTNFTFNILVPNNAGPADGLAFALVPVGSQPKDKGGFLGLFDGSNSNFHTVAVEFDTLYNKDWDPRERHIGIDVNSIKSIKTTPWDFVNGENAEVHITYESSTKLLVASLVYPSLKTSFTVSDTVDLKSVLPEWVSVGFSATTGITKGNVETNDILSWSFASKLSDGTTSEGLNLANLVLNQIL
What are the official names of this protein?
Leucoagglutinating phytohemagglutinin, PHA-L.
What is the protein family that this protein belongs to?
Belongs to the leguminous lectin family.
Protein: NTF3_ANISC
Sequence: IQSTSMDQGSLSEDSMNSFIRTLIQAGIWKNKVPRQMTRTQDGIQTIVKKTEDEPDATASKDISLGFQPIVSMDAELLRQQRRFSSPRVLLSENTPLEPPPLYLMEEPMVLNRTSRRKRFAEGKSHRGEYSVCDSESRWVTDKSSAVDIRGHQVTVLGEIRMGPS
What is the function of this protein?
Seems to promote the survival of visceral and proprioceptive sensory neurons.
What are the official names of this protein?
Neurotrophin-3, NT-3.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: ZFP37_MOUSE
Sequence: MATSEPAESDAVRAKEWEQLEPVQRDVYKDTKLENCSNPASMGNQDPKQDIVSVLEEEEPSSGKGKKASPSSLKKIARPKTAGTSAKLQQDDEHREEKQKSQSKLTKEVTLRKKSSNSKKSSEYGLLENKSLHSKHTPSEKKLLKSSSRGKNSNQNSDSLKKKPDTANDHRKSLSHSASDVNKDEIPTRKKCDKLPNNKLSDKGDKNQTSKKCEKVCRHSASHTKEDKIQTGEKRKSHCRTPSKPEKAPGSGKPYECNHCGKVLSHKQGLLDHQRTHTGEKPYECNECGIAFSQKSHLVVHQRTHTGEKPYECEQCGKAHGHKHALTDHLRIHTGEKPYKCNECGKTFRHSSNLMQHLRSHTGEKPYECKECGKSFRYNSSLTEHVRTHTGEIPYECNECGKAFKYGSSLTKHMRIHTGEKPFECNECGKTFSKKSHLVIHQRTHTKEKPYKCDECGKAFGHSSSLTYHMRTHTGDCPFECNQCGKAFKQIEGLTQHQRVHTGEKPYECVECGKAFSQKSHLIVHQRTHTGEKPFECYECGKAFNAKSQLVIHQRSHTGEKPYECIECGKAFKQNASLTKHMKIHSEEQSEEED
What is the function of this protein?
May have a role in regulating spermiogenesis.
What are the official names of this protein?
Zinc finger protein 37, Zfp-37, Male germ cell-specific zinc finger protein.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYAC_MOUSE
Sequence: MDATLTAREIRERFINFFRRNEHTYVHSSATIPLDDPTLLFANAGMNQFKPIFLNTIDPSHPMAKLSRAANTQKCIRAGGKHNDLDDVGKDVYHHTFFEMLGSWSFGDYFKELACKMALELLTQEFGIPVERLYVTYFGGDEAAGLEPDLECRQIWQNLGLDEARILPGNMKDNFWEMGDTGPCGPCSEIHYDRIGGRDAAHLVNQDDPNVLEIWNLVFIQYNRESDGVLKPLPKKSIDTGMGLERLVSVLQNKMSNYDTDLFMPYFEAIQKGTGARPYTGKVGAEDADGIDMAYRVLADHARTITVALADGGRPDNTGRGYVLRRILRRAVRYSHEKLNASRGFFATLVDVVVQSLGDAFPELKKDPEMVKDIINEEEVQFLKTLSRGRRILDRKIQSLGDCKTIPGDTAWLLYDTYGFPVDLTGLIAEEKGLVVDMNGFEEERRLAQLKSQGKGAGDEDLIMLDIYAIEELRAKGLEATDDSPKYNYQSDSSGSYVFECTVATVLALRREKMFVDEVVTGQECGVVLDKTCFYAEQGGQIYDEGYLVKVDDSSEDKTEFTVKNAQVRGGYVLHIGTIYGNLKVGDQVRLFIDEPRRRPVMSNHTATHILNFALRSVLGEADQKGSLVAPDRLRFDFTAKGAMSTQQIKKAEEIVNGMIEAAKPVYTQDCPLAAAKAIQGLRAVFDETYPDPVRVVSIGVPVSELLDDPCGPAGSLTSVEFCGGTHLRNSSHAGAFVIVTEEAIAKGIRRIVAVTGAEAQKALRKSETLKKSLSAMEAKVKAQTAPNKDVQREIADLGEALATAVIPQWQKDEQRETLKSLKKVMDDLDRASKADVQKRVLEKTKQLIDSNPNQPLVILEMESGASAKALNEALKLFKTHSPQTSAMLFTVDNEAGKITCLCQVPQNAANRGLKASEWVQQVSGLMDGKGGGKDMSAQATGKNVGCLQEALQLATSFAQLRLGDVKN
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala) (PubMed:16906134, PubMed:20010690, PubMed:25422440, PubMed:27622773).  Also edits incorrectly charged tRNA(Ala) via its editing domain (PubMed:16906134, PubMed:20010690, PubMed:25422440, PubMed:29769718).
What are the official names of this protein?
Alanine--tRNA ligase, cytoplasmic, Alanyl-tRNA synthetase, AlaRS, Protein sticky, Sti.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_MESH2
Sequence: MKISIISFGSSPREWLGLYKKEINKIKQFKYQIEFINLSEHSQENIELKKMLETKDILQKIPKNSSCYLFTERGKTVTSKEFSQLLNFSNICFIIGGSYGVDEKLIAKSRPDIGFLSFGKLTFAHKIFKLIVLEQIYRGFSIKFNRKYHHAD
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.