PharMolix/UniProtQA huggingface dataset:
Protein: URAA_ECO57
Sequence: MTRRAIGVSERPPLLQTIPLSLQHLFAMFGATVLVPVLFHINPATVLLFNGIGTLLYLFICKGKIPAYLGSSFAFISPVLLLLPLGYEVALGGFIMCGVLFCLVSFIVKKAGTGWLDVLFPPAAMGAIVAVIGLELAGVAAGMAGLLPAEGQTPDSKTIIISITTLAVTVLGSVLFRGFLAIIPILIGVLVGYALSFAMGIVDTTPIINAHWFALPTLYTPRFEWFAILTILPAALVVIAEHVGHLVVTANIVKKDLLRDPGLHRSMFANGLSTVISGFFGSTPNTTYGENIGVMAITRVYSTWVIGGAAIFAILLSCVGKLAAAIQMIPLPVMGGVSLLLYGVIGASGIRVLIESKVDYNKAQNLILTSVILIIGVSGAKVNIGAAELKGMALATIVGIGLSLIFKLISVLRPEEVVLDAEDADITDK
What is the function of this protein?
Transport of uracil in the cell.
What are the official names of this protein?
Uracil permease, Uracil transporter, Uracil/H(+) symporter UraA.
What is the protein family that this protein belongs to?
Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ADCA_STRP6
Sequence: MKKKILLMMSLISVFFAWQLTQAKQVLAEGKVKVVTTFYPVYEFTKGVIGNDGDVSMLMKAGTEPHDFEPSTKDIKKIQDADAFVYMDDNMETWVSDVKKSLTSKKVTIVKGTGNMLLVAGAGHDHHHEDADKKHEHNKHSEEGHNHAFDPHVWLSPYRSITVVENIRDSLSKAYPEKAENFKANAATYIEKLKELDKDYTAALSDAKQKSFVTQHAAFGYMALDYGLNQISINGVTPDAEPSAKRIATLSKYVKKYGIKYIYFEENASSKVAKTLAKEAGVKAAVLSPLEGLTEKEMKAGQDYFTVMRKNLETLRLTTDVAGKEILPEKDTTKTVYNGYFKDKEVKDRQLSDWSGSWQSVYPYLQDGTLDQVWDYKAKKSKGKMTAAEYKDYYTTGYKTDVEQIKINGKKKTMTFVRNGEKKTFTYTYAGKEILTYPKGNRGVRFMFEAKEPNAGEFKYVQFSDHAIAPEKAEHFHLYWGGDSQEKLHKELEHWPTYYGSDLSGREIAQEINAH
What is the function of this protein?
Part of the ATP-driven transport system AdcABC for zinc.
What are the official names of this protein?
Zinc-binding protein AdcA.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 9 family.
Protein: RNH_POLSJ
Sequence: MTDTQAGTTTQTQVVIYTDGACKGNPGPGGWGVLLAMGDTEKELFGGEPVTTNNRMEMTAVIEALAALKRPCRVTLYLDSEYVRKGITEWIHGWKARGWRTAAKAPVKNVDLWQRLDALVTSSGHKIDWRWVKGHNGDPGNERADALANQGVERALGRR
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOD1_ANASK
Sequence: MEKLILRRVDRQNEEMILNFGPQHPSTHGVINFLVETDGEVLKRATPDVGYLHRSIEKIGEMVGYPGFMPYTDRVDYVAAMFANEGYAIAVERLLKIEVPQRAQWLRAISCELCRIASHLVSVGTMVMDIGAFTPMLHGIRERETINDLLEALCGARLTYNYHRIGGVAFDLPEGWRDKVLHFLDHFDKFLAEFDRLISFNEIYVKRLANVAVIPGPMAINYGLVGPNLRGSGVDWDVRRDLPYGAYPNFKFDVPVGKGFFGTSGDSFDRYYVRCLEMAESSKIVRQALDSLPEGEITAKVPRNIKPEAGEAIGRVESARGELAYYVISDGTNKAYRVRARTGSFTAMCIIEDISRGLMVADLVALISSLDVVAPEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D 1, NADH dehydrogenase I subunit D 1, NDH-1 subunit D 1.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: COX2_ORNAN
Sequence: MAYPLQLGFQDATSPIMEELLHFHDHTLMIVFLISSLVLYIISTMLTTKLTHTNTMDAQEVETIWTILPAIILILIALPSLRILYMMDEINNPNLTIKTLGHQWYWSYEYSDYEDLSFDSYMIPTQDLLPGQLRLLEVDNHLVLPIELPIRMLISSEDVLHSWALPSMGLKTDAIPGRLNQATITSTRPGLFYGQCSEICGSNHSFMPIVLEMVPLKYFENWTSSMMSTS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: AFDDT_HUMAN
Sequence: MGAAGSDGRCCVRSGRAGTGGAGSKWVVMDLWTGGAGSRRAVLGPDGRWVRWAVLGSVRMGGARSKWAAPDPMGGAGFGPDWRVRVWTGGAGSKWGCSAGSGRAVLGPNGRWVPWAVLGSVRTGGAGSKWAALGPMGGTGSGRAVLGLDGRCSIQMGAAGSGRAVLGSVRTGGAGSKWAVLGSAGDRWAWRHRYGAQGRWSALSEGPCAPRARCSSCPRIAPGLLRVSSRVIPFRWVTSKPTFSSCFLPRRTRC
What are the official names of this protein?
Putative uncharacterized protein AFDN-DT, AFDN divergent transcript, Protein HGC6.4.
Protein: GRK6_HUMAN
Sequence: MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQPIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPEVPRQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLCSQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDIEQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWKGQPPAPPKKGLLQRLFSRQDCCGNCSDSEEELPTRL
What is the function of this protein?
Specifically phosphorylates the activated forms of G protein-coupled receptors.  Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization.  Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis (By similarity).  Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling (in vitro).
What are the official names of this protein?
G protein-coupled receptor kinase 6, G protein-coupled receptor kinase GRK6.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
What are the subcellular locations of this protein?
Membrane; Lipid-anchor.
Protein: FBK12_ARATH
Sequence: MRRRRCDLQPKRTRMCDLQPKRTSMCDLPPKLVGEKILTRIPITSLRAVRSTCKLWNALTKDRVLGKAAAQFLGFMTMDSKVCSVRFHLRRSKEEEEDTMDLSIKQVDLLNQVEISRVYHCDGLLLCVAKDNSRVVVWNPYLGQTRWIRPRTESNIGDSYALGYDINRNHKILRMVQTRNVSVYRYEIYDLRSNSWRVLEVTPNGEMDPNHPLYGVSVKGNTYFFAHEDSSSGEIDEDGDIIDLEDFLLCFDFTTETFGLRLPLPFHSTIDATVTLSCVRDQQLAVLYHNEGLHSDDRFTTVEFWVTTSIEPNSVSWSKFLTVDMRPLALTGVRFDNDMGATFFIDEDEKVAVVFDLDGYLSTESARYHTAFISGKDGFFKPVTLGVAPNVGEPCPRTGHIPTTYRPPLVCSSTYLPSLVQVNQQRKRKERHV
What are the official names of this protein?
F-box/kelch-repeat protein At1g25055.
Protein: TXBB_ANDCR
Sequence: ADVPGNYPLNSYGASYYCTI
What is the function of this protein?
Binds to sodium channels (Nav) and affects the channel activation process.
What are the official names of this protein?
Toxin b subunit beta.
What are the subcellular locations of this protein?
Secreted.
Protein: PURR_HAEI8
Sequence: MATIKDVAKMAGVSTTTVSHVINKTRFVAKDTEEAVLSAIKQLNYSPSAVARSLKVNTTKSIGMIVTTSEAPYFAEIIHSVEEHCYRQGYSLFLCNTQNDPEKVKNHLEMLAKKRVDGLLVMCSEYTQDSLDLLSSFSTIPMVVMDWGPNANTDVIDDHSFDGGYLATKHLIECGHKKIGIICGELNKTTARTRYEGFEKAMEEAKLTINPSWVLEGAFEPEDGYECMNRLLTQEELPTALFCCNDVMALGAISALTEKGLRVPEDMSIIGYDDIHASRFYAPPLTTIHQSKLRLGRQAVNILLERITHKDEGVQQYSRIDITPELIIRKSVKSIL
What is the function of this protein?
Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression.  PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.
What are the official names of this protein?
HTH-type transcriptional repressor PurR, Pur regulon repressor, Purine nucleotide synthesis repressor.
Protein: ECCE5_MYCMM
Sequence: MKAQRRFGLALSWARLTTVFVIDLLILIVASHCPDSWQGENRIAWWVGVGIAVLVTLLSVVTYRGITVTSGITAWLWDWSADPGTALGAGCTPAVDHQRRFGRDTVGVREHHGRLVTVITVDDGEGDAAGRHRHRTTQSAVVPVATVAENLRQFDVQLDGVDIVTVEVRGGAEAARASASLDEWGPEEWGMVGESPAANRRRTWLILRMNPQRNVAAIASRDSLASTLVTATERLAQVLDGQSCAARPLAADELAEVDSAILAELEPTWSRPGWRHLKHFNGYATSFWVTPADINAETLDEVWLSDAPEVGATVLTLRLVMRAGEPRLSAWVRYHSDERLPKELSVGLNRLTGRQLAAVRASLPVPSTRAQLVVSSRELLDHDELELPVGQTQEHATSATTGQ
What is the function of this protein?
Part of the ESX-5 specialized secretion system, which is responsible for the secretion of EsxN and a number of PE_PGRS and PPE proteins.
What are the official names of this protein?
ESX-5 secretion system protein EccE5, ESX conserved component E5, Type VII secretion system protein EccE5, T7SS protein EccE5.
What is the protein family that this protein belongs to?
Belongs to the EccE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS2_CERS1
Sequence: MTVLERLAATVEARKGADPDSSWTAKLLAKGPEKCAEKFGEEAVEAIIEAVRGDRARLASEAADVLYHLLVMLAARDVTLAEVMAVLEAREGTSGIAEKAGRG
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTTC1_METAC
Sequence: MASKEEIIAKAKDAITDFDEELAAEVAEEALAAGIDPVELIEKGFTAGMQEVGEQFEQGSLFLPHVLAAAEAMNTGMEVIKPEMEKRKSETKSLGTVVIGTIEGDIHSIGKDIVASMLNIAGFKVVDLGRDVPIKTFVEKAKEVKPQIIASSALMTTTMVNQIQIEEQLKEAGIRDQVKTMVGGAPVTQDWADKIGADLYGESATDVVSKVRAVLL
What is the function of this protein?
Acts probably as a methyl group carrier between MttB and either MtbA or MtaA.
What are the official names of this protein?
Trimethylamine corrinoid protein 1, TCP 1.
What is the protein family that this protein belongs to?
Belongs to the methylamine corrinoid protein family.
Protein: SIM15_HUMAN
Sequence: MFDIKAWAEYVVEWAAKDPYGFLTTVILALTPLFLASAVLSWKLAKMIEAREKEQKKKQKRQENIAKAKRLKKD
What are the official names of this protein?
Small integral membrane protein 15.
What is the protein family that this protein belongs to?
Belongs to the SMIM15 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: YECN_ECOL6
Sequence: MVSALYAVLSALLLMKFSFDVVRLRMQYRVAYGDGGFSELQSAIRIHGNAVEYIPIAIVLMLFMEMNGAETWMVHICGIVLLAGRLMHYYGFHHRLFRWRRSGMSATWCALLLMVLANLWYMPWELVFSLR
What are the official names of this protein?
Inner membrane protein YecN.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: PETG_NOSS1
Sequence: MVEPLLSGIVLGLIVVTLAGLFYAAYKQYKRPNELGG
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: SG1D_BOVIN
Sequence: MRLSVTALLVTLALCYYEANAIVCPTFAADLTEFFYFPDLLYRLSLAKYNAPPEAVAAKMEVKQCTDRFSVKNRLIITNILGKILLNCTVTDVKAVLNPSSA
What is the function of this protein?
May bind androgens and other steroids.  May be under transcriptional regulation of steroid hormones (By similarity).
What are the official names of this protein?
Secretoglobin family 1D member, LppAB.
What is the protein family that this protein belongs to?
Belongs to the secretoglobin family. Lipophilin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: EFG_GEOTN
Sequence: MAREFSLENTRNIGIMAHIDAGKTTTTERILFYTGRVHKIGETHEGSATMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGAITVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKIGADFLYAVKTLHDRLQANAYPVQLPIGAEDQFTGIIDLVEMCAYHYHDDLGKNIERIEIPEDYRDLAEEYHGKLIEAVAELDEELMMKYLEGEEITKEELKAAIRKATINVEFYPVFCGSAFKNKGVQLLLDGVVDYLPSPLDIPAIRGIIPDTEEEVAREARDDAPFSALAFKIMTDPYVGKLTFFRVYSGTLDSGSYVMNSTKRKRERIGRLLQMHANHRQEISTVYAGDIAAAVGLKETTTGDTLCDEKNLVILESMQFPEPVISVAIEPKSKADQDKMGQALQKLQEEDPTFRAHTDPETGQTIISGMGELHLDIIVDRMRREFKVEANVGAPQVAYRETFRQSAQVEGKFIRQSGGRGQYGHVWIEFTPNERGKGFEFENAIVGGVVPKEYVPAVQAGLEEAMQNGVLAGYPVVDIKAKLFDGSYHDVDSSEMAFKIAASMALKNAAAKCEPVLLEPIMKVEVVIPEEYLGDIMGDITSRRGRVEGMEARGNAQVVRAMVPMAEMFGYATSLRSNTQGRGTFSMVFDHYEEVPKNIADEIIKKNKGE
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_RICRO
Sequence: MNIFNNNLHETDKEINEIIKHEKLRQSSVIELIASENFVSPAVLEAQGALLTNKYAEGYPSKRFYNGCEEVDKAENLAIERVKKLFNCKYANVQPHSGSQANQAVYLALLQPGDTVLGMSLDSGGHLTHGAAPNMSGKWFNAVSYSVNKETYLIDYDEIERLADLHKPKLLIAGFSAYPRNIDFAKFREIVDKVGAYFMADIAHIAGLVATGEHQSPIPYAHAVTSTTHKTLRGPRGGLILSNDEEIGHKINSALFPGLQGGPLMHIIAAKAVAFLENLQPEYKSYIQQVISNAKALASSLQERGYDILTGGTDNHIVLVDLRKDGITGKLAANSLDRAGITCNKNAIPFDETSPFITSGIRLGTPACTTRGFKEKDFVLVGHMVADILDGLKNNEDNSALEQQVLNEVTKLIELFPFYG
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPF_DESAP
Sequence: MEFTKMHGLGNDFVIVNGFGQSLPDDPGALARRVCDRRLGVGADGLVLLLPSAAADLRMRVFNPDGSEPEMCGNAIRCVALYARRRGLVAKTQLEVETLAGLIRPEILLDGDRETVRVDMGRPRLERAEIPMRGPAGPVVGEVLDAGERSFMVTAVSMGNPHCVVFGADLDDAGFRKYGPLLEVHPAFPARTNVEFVEVLSPGEVAVRVWERGVGPTPACGTGACAVAVAGVLTGRTARRVHVRLPGGVLLIEWPDDAGPVYMSGPAEEVFDGKWVRA
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRXC5_ORYSJ
Sequence: MQYGAAAAEQAWYMPAAAMVVAAAAETAAERVERLASESAVVVFSVSSCCMCHAVKRLFCGMGVHPAVHELDLDPRGRDLERALARLVGAGGAAAAAVPVVFIGGKLVGAMDRVMAAHINGSLVPLLKEAGALWL
What is the function of this protein?
Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase.  Reduces low molecular weight disulfides and proteins (By similarity).
What are the official names of this protein?
Glutaredoxin-C5, Protein ROXY 1.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family. CC-type subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: LRKS7_ARATH
Sequence: MSLSRKLLVIFFTWITALSMSKPIFVSSDNMNFTFKSFTIRNLTFLGDSHLRNGVVGLTRELGVPDTSSGTVIYNNPIRFYDPDSNTTASFSTHFSFTVQNLNPDPTSAGDGLAFFLSHDNDTLGSPGGYLGLVNSSQPMKNRFVAIEFDTKLDPHFNDPNGNHIGLDVDSLNSISTSDPLLSSQIDLKSGKSITSWIDYKNDLRLLNVFLSYTDPVTTTKKPEKPLLSVNIDLSPFLNGEMYVGFSGSTEGSTEIHLIENWSFKTSGFLPVRSKSNHLHNVSDSSVVNDDPVVIPSKKRRHRHNLAIGLGISCPVLICLALFVFGYFTLKKWKSVKAEKELKTELITGLREFSYKELYTATKGFHSSRVIGRGAFGNVYRAMFVSSGTISAVKRSRHNSTEGKTEFLAELSIIACLRHKNLVQLQGWCNEKGELLLVYEFMPNGSLDKILYQESQTGAVALDWSHRLNIAIGLASALSYLHHECEQQVVHRDIKTSNIMLDINFNARLGDFGLARLTEHDKSPVSTLTAGTMGYLAPEYLQYGTATEKTDAFSYGVVILEVACGRRPIDKEPESQKTVNLVDWVWRLHSEGRVLEAVDERLKGEFDEEMMKKLLLVGLKCAHPDSNERPSMRRVLQILNNEIEPSPVPKMKPTLSFSCGLSLDDIVSEDEEGDSIVYVVS
What is the function of this protein?
Involved in resistance response to the pathogenic oomycetes Phytophthora infestans and Phytophthora capsici.
What are the official names of this protein?
Probable L-type lectin-domain containing receptor kinase S.7, LecRK-S.7.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the leguminous lectin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: NUBP2_DROWI
Sequence: MLDKVKNVIVVLSGKGGVGKSTVSTQLALALRHTGHKVGLLDIDLCGPSVPYLLGLEGSDIYQCDDGWVPIYTDESKTLAVMSIGFLLKSRTDPVIWRGPKKTMMIKQFLQDVKWDELDYLIIDTPPGTSDEHITVMECLREVPCNGAIIVTTPQGVALDDVRKEITFCKKTGIKLLGIVENMSGFVCPHCTTCTNIFSSNGGIELANLAQIPHLGTLPIDPRVGILAGTTASVLSELPESSTAEVLKGLVQHLDTLTAQG
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery.  Required for maturation of extramitochondrial Fe-S proteins.  The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor NUBP2 homolog.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_STRTD
Sequence: MTNEFHHVTVLLHETVDMLDIKPDGIYVDATLGGAGHSSYLLSQLSEKGHLYCFDQDQKAIDNAQVRLKDYIDKGMVTFIKDNFRNLKSNLEALGVSEIDGILYDLGVSSPQLDERERGFSYKQDAKLDMRMNEEASLTAYDVVNTYPYNDLVRIFFKYGEDKFSKQIARKIEQARQVKPIETTTELAEIIKSAKPAKELKKKGHPAKQIFQAIRIEVNDELGAADESIQEALDLLAVDGRISVITFHSLEDRLTKQLFKEASTVDVPKGLPFIPEDLQPKVALVNRKPILPSQEELEANNRSHSAKLRVAKKIRK
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PKHG2_HUMAN
Sequence: MPEGAQGLSLSKPSPSLGCGRRGEVCDCGTVCETRTAPAAPTMASPRGSGSSTSLSTVGSEGDPAPGPTPACSASRPEPLPGPPIRLHLSPVGIPGSARPSRLERVAREIVETERAYVRDLRSIVEDYLGPLLDGGVLGLSVEQVGTLFANIEDIYEFSSELLEDLENSSSAGGIAECFVQRSEDFDIYTLYCMNYPSSLALLRELSLSPPAALWLQERQAQLRHSLPLQSFLLKPVQRILKYHLLLQELGKHWAEGPGTGGREMVEEAIVSMTAVAWYINDMKRKQEHAARLQEVQRRLGGWTGPELSAFGELVLEGAFRGGGGGGPRLRGGERLLFLFSRMLLVAKRRGLEYTYKGHIFCCNLSVSESPRDPLGFKVSDLTIPKHRHLLQAKNQEEKRLWIHCLQRLFFENHPASIPAKAKQVLLENSLHCAPKSKPVLEPLTPPLGSPRPRDARSFTPGRRNTAPSPGPSVIRRGRRQSEPVKDPYVMFPQNAKPGFKHAGSEGELYPPESQPPVSGSAPPEDLEDAGPPTLDPSGTSITEEILELLNQRGLRDPGPSTHDIPKFPGDSQVPGDSETLTFQALPSRDSSEEEEEEEEGLEMDERGPSPLHVLEGLESSIAAEMPSIPCLTKIPDVPNLPEIPSRCEIPEGSRLPSLSDISDVFEMPCLPAIPSVPNTPSLSSTPTLSCDSWLQGPLQEPAEAPATRRELFSGSNPGKLGEPPSGGKAGPEEDEEGVSFTDFQPQDVTQHQGFPDELAFRSCSEIRSAWQALEQGQLARPGFPEPLLILEDSDLGGDSGSGKAGAPSSERTASRVRELARLYSERIQQMQRAETRASANAPRRRPRVLAQPQPSPCLPQEQAEPGLLPAFGHVLVCELAFPLTCAQESVPLGPAVWVQAAIPLSKQGGSPDGQGLHVSNLPKQDLPGIHVSAATLLPEQGGSRHVQAPAATPLPKQEGPLHLQVPALTTFSDQGHPEIQVPATTPLPEHRSHMVIPAPSTAFCPEQGHCADIHVPTTPALPKEICSDFTVSVTTPVPKQEGHLDSESPTNIPLTKQGGSRDVQGPDPVCSQPIQPLSWHGSSLDPQGPGDTLPPLPCHLPDLQIPGTSPLPAHGSHLDHRIPANAPLSLSQELPDTQVPATTPLPLPQVLTDIWVQALPTSPKQGSLPDIQGPAAAPPLPEPSLTDTQVQKLTPSLEQKSLIDAHVPAATPLPERGGSLDIQGLSPTPVQTTMVLSKPGGSLASHVARLESSDLTPPHSPPPSSRQLLGPNAAALSRYLAASYISQSLARRQGPGGGAPAASRGSWSSAPTSRASSPPPQPQPPPPPARRLSYATTVNIHVGGGGRLRPAKAQVRLNHPALLASTQESMGLHRAQGAPDAPFHM
What is the function of this protein?
May be a transforming oncogene with exchange activity for CDC42 (By similarity).  May be a guanine-nucleotide exchange factor (GEF) for RAC1 and CDC42.  Activated by the binding to subunits beta and gamma of the heterotrimeric guanine nucleotide-binding protein (G protein) (PubMed:18045877).  Involved in the regulation of actin polymerization (PubMed:26573021).
What are the official names of this protein?
Pleckstrin homology domain-containing family G member 2, PH domain-containing family G member 2.
Protein: T38B1_CAEEL
Sequence: MVVPESFQLDQEILLDAGAQLHRLKMYPYFDVAHYLLMIIEVRDDLGSAASIFSRKHPLSCWLSSMLMCFADAFLANFLLGEPVIAPFKRHDDIILATIIWYLVFYAPFDGIYKIAKITPVKCVLAVMKEVKRAYKVSHGVSHAAKLYPNSYIVQVLVGTAKGAGSGIVRTLEQLVRGVWLPTHNELLRPSFATKACVVAASVLALEKSGTYLTAPHDLVYLVIVGFFVYFKLSAVILHVTDPFAPIENLFCAIFMGGIWDAVSRALAASRDRRAAGAHSNENGSSISTPEKKDQ
What is the function of this protein?
Potassium channel that mediates transmembrane potassium transport (PubMed:27698420).  Might be required for maintenance of rapid intracellular calcium release (By similarity).  May act as a counter-ion channel that functions in synchronization with calcium release from intracellular stores (By similarity).  Binds phosphatidylinositol 4,5-bisphosphate (PIP2) (PubMed:27698420).
What are the official names of this protein?
Trimeric intracellular cation channel type 1B.1, TRIC-1B.1, TRIC-B1.
What is the protein family that this protein belongs to?
Belongs to the TMEM38 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: DCTN5_MOUSE
Sequence: MELGELLYNKSEYIETASGNKVSRQSVLCGSQNIVLNGKTIIMNDCIIRGDLANVRVGRHCVVKSRSVIRPPFKKFSKGVAFFPLHIGDHVFIEEDCVVNAAQIGSYVHVGKNCVIGRRCVLKDCCKILDNTVLPPETVVPPFTVFSGCPGLFSGELPECTQELMIDVTKSYYQKFLPLTQV
What is the function of this protein?
Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules.
What are the official names of this protein?
Dynactin subunit 5, Dynactin subunit p25.
What is the protein family that this protein belongs to?
Belongs to the dynactin subunits 5/6 family. Dynactin subunit 5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Chromosome, centromere, kinetochore.