PharMolix/UniProtQA huggingface dataset:
Protein: RUVB_HELAH
Sequence: MKERIVNLETLDFETSQEVSLRPDLWENYIGQEKIKNNLQISICAAKKRQESLDHMLFFGPPGLGKTSISHIIAKEMETNIKITAAPMIEKSGDLAAILTNLQAKDILFIDEIHRLSPAIEEVLYPAMEDFRLDIIIGSGPAAQTIKIDLPPFTLIGATTRVGMLSNPLRDRFGMSFRMQFYSPSELALIIKKAATKLNQDIKEESADEIAKRSRGTPRIALRLLKRVRDFALVKNSSLMDLNITLHALNELGVNELGFDEADLAYLSLLANAQGKPVGLNTIAASMREDESTIEDVIEPFLLANGYLERTAKGRIATPKTHALLKIPTLKSQSLF
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: MRPF_BACSU
Sequence: MFTLILQIALGIMAVSTFLYVIRVIKGPTVPDRVVALDAIGINLIAITALVSILLKTSAFLDIILLLGILSFIGTIAFSKFLEKGEIIENDRNR
What is the function of this protein?
Involved in cholate and Na(+) efflux activities, which may be mechanistically coupled.  Does not require other Mrp proteins for its own function.
What are the official names of this protein?
Na(+)/H(+) antiporter subunit F, Mrp complex subunit F, Multiple resistance and pH homeostasis protein F, Sodium-cholate efflux protein MrpF.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PG190_VACCC
Sequence: MKTISVVTLLCVLPAVVYSTCTVPTMNNAKLTSTETSFNNNQKVTFTCDQGYHSSDPNAVCETDKWKYENPCKKMCTVSDYISELYNKPLYEVNSTMTLSCNGETKYFRCEEKNGNTSWNDTVTCPNAECQPLQLEHGSCQPVKEKYSFGEYMTINCDVGYEVIGASYISCTANSWNVIPSCQQKCDIPSLSNGLISGSTFSIGGVIHLSCKSGFILTGSPSSTCIDGKWNPVLPICVRTNEEFDPVDDGPDDETDLSKLSKDVVQYEQEIESLEATYHIIIVALTIMGVIFLISVIVLVCSCDKNNDQYKFHKLLP
What is the function of this protein?
Plays a role in the dissolution of the outermost membrane of extracellular enveloped virions (EV) to allow virion entry into host cells.  Participates also in wrapping mature virions (MV) to form enveloped virions (EV).
What are the official names of this protein?
Protein OPG190, Plaque-size/host range protein.
What is the protein family that this protein belongs to?
Belongs to the receptors of complement activation (RCA) family.
Protein: EFP_BRUO2
Sequence: MKINGNEIRPGNVIEHEGGLWVAVKTNAVKPGKGGAYNQVELKNLINGTKLNERFRAAETVERVRLEQKDFSFLYEQGEALIFMDTETYEQLELQKDFVGDRAAFLQDGMMVTVELYEEKPIGIRLPDQVTLAITEADPVVKGQTAASSYKPAVLENGIRIPVPPFITSGERVIVDTNELTYISRA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OAT_BORPE
Sequence: MPAPAATRRDRIEDELGAHNYQPLDVVLARGSGVWLYDTAGRRYLDCLSAYSAVNQGHCHPRILAAMVEQAQRLTLTSRAFRHDQLAPLYEDLARLTGAHKVLPMNSGAEAVETALKAVRKWGYEARGVPAGQAEIIVCANNFHGRTLGIVGFSTDPDARGGYGPFAPGFTVVPFGDFAALQAAVTPRTVAFLVEPIQGEAGVILPPPGYFRQVRKLCSERDIVLILDEIQTGLGRTGAFLAEAHEGIEADVTLIGKALSGGFYPVSAVLSNQAVLGIFQPGQHGSTFGGNPLACAVARAALRVLHDEGMIDNAREQGAYFMQRLRALPGPVREVRGRGLMLALELEPDAGPARAYCERLMARGMLVKDTHGQTLRLSPPLIVTREQIDWACAQLAHVLAHSAPGSSGGPS
What is the function of this protein?
Catalyzes the interconversion of ornithine to glutamate semialdehyde.
What are the official names of this protein?
Ornithine aminotransferase, OAT, Ornithine--oxo-acid aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOAA_CLOP1
Sequence: MKDKYGREIDYLRISLTDKCNLRCAYCMEKDHNDFIHNDKLMTLDEILRVVKECASIGIKKVRLTGGEPLVREGVVDLIKNINKIPEIEEICLTTNGILLGDKVKELSENGLKRVNISLDTLKEDRFKEITRIGTLDKVLYSIEKCLENNVKVKINTIILEDFNKDEILDLINLAYKNPIDLRFIELMPIGEGKKFKGVTNSEILEIIKKEKKVLSDGKTLRLNGPAKYISIEGFKGKIGFISAMSDCFCEDCNRIRVTPEGFMKQCLHWKYGINLRDKMRNGISDEELREIIKKSIYEKPEKHNFKMKEKDEDKRFMYEIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: DHE4_UNKP
Sequence: MEYAVSVESFLSSLQRHNPHQPEYLQAVREVFTSLWPFIERNPAYREQALLERLVEPERIIQFRVSWVDDRGQVQVNRAFRVQFNSAIGPYKGGMRFHPSVNLSILKFLGFEQTFKNALTTLPMGGGKGGSDFDPKGKSQGRIMRFCQALMTELYRHLGPDTDVPAGDIGDGGREVGFMAGMMKKLSNNTACVFTGKGLSFGGSLIRPEATGYGLVYFTDAMLQRHGLGFEGMRVAVSGSGNVAQYTIEKALELDARVITVSDSGGTLVDEDGFTTEKLAHLAEIKNQRYGRVADYAAERGLTYLAGQQPWNVPVDIALPCATQNELDLEAARVIRNGVKAVAEGANMPTTIQATDAFLDAGVLFAPGKAANAAGLATSGLEMAQNAARIGWRAEKVDVRLQHIMADIHHACVEYGGEGKQTHYVHGANIAGFVKVAEAMLAQGVL
What is the function of this protein?
Catalyzes the reversible oxidative deamination of glutamate to a-ketoglutarate and ammonia.
What are the official names of this protein?
NADP-specific glutamate dehydrogenase, NADP-GDH.
What is the protein family that this protein belongs to?
Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
Protein: CUL3_CAEEL
Sequence: MSGRSGNGGQQKMRIRPFMATIDEQYVTQTWELLKRAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGERLYNGLKDVIQDHMASVRIRIIESMNSGSFLETVAESWADHTVAMVMIRDILMYMDRIYVAQNNHVLPVYNLGLDAYRTEILRQNGIGDRIRDALLELIKLDRKSNQINWHGIKNACDMLISLGIDSRTVYEDEFERPLLKETSDYYRDVCKNWLSGDNDACFYLAQVEIAMHDEASRASRYLDKMTEAKILQVMDDVMVAEHIQTIVYMQNGGVKFMLEHKKIEDLTRIFRIFKRIGDSVTVPGGGLKALLKAVSEYLNETGSNIVKNEDLLKNPVNFVNELLQLKDYFSSLLTTAFADDRDFKNRFQHDFETFLNSNRQSPEFVALYMDDMLRSGLKCVSDAEMDNKLDNVMILFRYLQEKDVFEKYFKQYLAKRLLLDKSCSDDVEKALLAKLKTECGCQFTQKLENMFRDKELWLTLATSFRDWREAQPTKMSIDISLRVLTAGVWPTVQCNPVVLPQELSVAYEMFTQYYTEKHTGRKLTINTLLGNADVKATFYPPPKASMSNEENGPGPSSSGESMKERKPEHKILQVNTHQMIILLQFNHHNRISCQQLMDELKIPERELKRNLQSLALGKASQRILVRKNKGKDAIDMSDEFAVNDNFQSKLTRVKVQMVTGKVESEPEIRETRQKVEDDRKLEVEAAIVRIMKARKKLNHNNLVAEVTQQLRHRFMPSPIIIKQRIETLIEREYLARDEHDHRAYQYIA
What is the function of this protein?
Probable core component of multiple cullin-RING-based BCB (BTB-CUL3-BTB) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:13679922).  Probably acts as a scaffold protein which may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme (PubMed:13679922).  Required to target mei-3/katanin for degradation at the meiosis to mitosis transition via its neddylation and deneddylation (PubMed:12781129).  Functions in ubiquitin-mediated degradation of CKIs to target cki-1 for degradation (PubMed:12781129).  Regulates microtubule stability in the early embryo (PubMed:12781129).  In body wall muscles, involved in the organization of myosin thick filaments, likely by regulating the degradation of microtubule severing protein mei-1 downstream of unc-89 (PubMed:22621901).  Together with spop-1, may promote the ubiquitination and proteasomal degradation of target bromodomain-containing proteins such as bet-1 (PubMed:34593637).
What are the official names of this protein?
Cullin-3, CUL-3.
What is the protein family that this protein belongs to?
Belongs to the cullin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: HSP71_CANAL
Sequence: MSKAVGIDLGTTYSCVAHFANDRVEIIANDQGNRTTPSFVAFTDTERLIGDAAKNQAAMNPANTVFDAKRLIGRKFDDPEVINDAKHFPFKVIDKAGKPVIQVEYKGETKTFSPEEISSMVLTKMKEIAEGYLGSTVKDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKGSRGEHNVLIFDLGGGTFDVSLLAIDEGIFEVKATAGDTHLGGEDFDNRLVNFFIQEFKRKNKKDISTNQRALRRLRTACERAKRTLSSSAQTSIEIDSLYEGIDFYTSITRARFEELCADLFRSTLDPVGKVLADAKIDKSQVEEIVLVGGSTRIPKIQKLVSDFFNGKELNKSINPDEAVAYGAAVQAAILTGDTSSKTQDILLLDVAPLSLGIETAGGIMTKLIPRNSTIPTKKSETFSTYADNQPGVLIQVFEGERAKTKDNNLLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVSALEKGTGKTQKITITNDKGRLSKEEIDKMVSEAEKFKEEDEKEAARVQAKNQLESYAYSLKNTINDGEMKDKIGADDKEKLTKAIDETISWLDASQAASTEEYEDKRKELESVANPIISGAYGAAGGAPGGAGGFPGAGGFPGGAPGAGGPGGATGGESSGPTVEEVD
What is the function of this protein?
May play a role in the transport of polypeptides both across the mitochondrial membranes and into the endoplasmic reticulum.
What are the official names of this protein?
Heat shock protein SSA1.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted, cell wall.
Protein: ATP8_RAT
Sequence: MPQLDTSTWFITIISSMATLFILFQLKISSQTFPAPPSPKTMATEKTNNPWESKWTKTYLPLSLPPQ
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, Chargerin II, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: RLMN_BURCH
Sequence: MTSETSVNLLDFDAEGLVAYCGSLGEKPFRAKQLQRWIHQYNAGDFDGMTDLAKSLREKLKGRASIVMPDIASDHVSTDGTRKWLIDVGNGNAVETVFIPEETRGTLCVSSQAGCAVNCRFCSTGKQGFSRNLSTAEIIGQLRMAEFALRASLGRAPGPNGKAERVVTNVVMMGMGEPLLNYSAVVPAMRLMLDDNAYGLSRRRVTLSTSGVVPMMDRLGAELPVALAVSLHAPNDALRDELVPLNKKYPLRELMAACQRYLKVAPRDFITFEYCMLDGVNDTEAHARELLAVTRDVPCKFNLIPFNPFPESGLIRSKPEQIKRFAQVLIDAGVVTTVRKTRGDDIDAACGQLAGAVKDRTRLAERTGAAGKIIEVRAV
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YSFE_BACSU
Sequence: MALNTRESARDITALDIPDTSASNTFEIGFVTENVEAVIKRMREQGVSIIGEPKVKPWGQTVAYIADPDGHYIEICSPME
What are the official names of this protein?
Uncharacterized protein YsfE.
Protein: MNMA_SHEB8
Sequence: MTSIEPTHTGKKVIVGMSGGVDSSVSAYLLMQQGYQVEGLFMKNWEEDDNNEYCAAAEDLKDAQAVCDKLGIKLHTVNFAAEYWDNVFEYFLAEYKAGRTPNPDIMCNKEIKFKAFLEFADEILDADYIAMGHYVRRRDNSDGSTQMLRGVDGNKDQSYFLYTLSHEQVARSLFPVGELEKHEVREIAKEMGLITHDKKDSTGICFIGERKFTEFLGTYLPAQPGNIETPEGEVIGTHQGLMYHTLGQRKGLGIGGMKNSNDDPWYVVDKDLERNVLIVGQGGHHPRLMSTGMTVNQLHWVDRTGPVDGCHIAVKTRYRQQDVPCTLTYTDEHTLRVVFDEPVAAVTPGQSAVFYDGEVCLGGGIIDQLIRG
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE1_POLNA
Sequence: MATIGRRAYAEMFGPTVGDRLRLADTDLMVEVEADYTLRAGGYGEEVKFGGGKTIRDGMAQSQRTNAEGAMDTVMTNALILDHWGIVKADIGLKGGRIAAIGKAGNPDVQPGVDIIIGPGTEIISCEGMIVTAGGIDSHIHFICPQQIEEALTSGVTTMMGGGTGPATGTFATTCTPGPWNIARMLQAADAFPMNLGFLGKGNASLPAALHEQVNAGVIGLKLHEDWGTTPAAISNCLDVAEETDVQVAIHSDTLNESGFVENTIAATKGRSLCAFHTEGAGGGHAPDILRVVGEANFLPSSTNPTMPYTVNTLDEHVDMLMVCHHLDPAIAEDLAFAESRIRKETIAAEDILHDLGAISMMSSDSQAMGRVGEVIIRTWQNAHKMKQQRGKLPGDTERHDNFRVKRYIAKYTINPAIAHGISHEVGSIEVGKFADLVVWKPAFFGIKPSIILKGGFIAMAAMGDPNASIPTPQPVHYRPMFGAFGGATARGSLTFVSQAGLAAGIKERFGLAKTLSAVKNIRGVRKQHMIHNNYLPKMEIDAQTYLVRADGQLLTCEPASSLPMTQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y020_HAEIN
Sequence: MALSKNTKLVILMAIPLITFLLPAPDGLSLIAWRLLGVYIATIVGLVLKPYGEPVILLAAIAVSGVIIGNTEGAKELVKVGNMLDGYKSGTTWLIFTAFTLSSAFVITGLGKRIAYHMIGAMGSTTLRLGYVTMFLDLLLSPATPSNTARSGGIIFPIINSVVVALGSDPEKSPKKAGRYLMMNVYMVVKTTSYIFLTAMAPNALALSLMAPILGFETTWIKWFLAASVPGLLCLFLIPLICYWVSPPELKKVDNKAIAKKGLEELGPMSFREKALSVLFVIALFGWIFSNSLHINATIVAIIVMVLCIVLSIVTWDDILKSKGAWNTLVWYGGIIGMSGLLEKSGFFKWLANTLSTILQFEGHGMMALIVILTLSVSVRYLFASGGAYVAAMVPVFATVGHVTGAPTELLALGLVFANSYGGSVTHYGGGPGPIAFGAGYNDIKSWWITGAIIAFGSLIIHLTIGMAWWKLLMSLGWL
What are the official names of this protein?
Uncharacterized transporter HI_0020.
What is the protein family that this protein belongs to?
Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RR7_PAUCH
Sequence: MSRRNAAEKRPVLPDPQFNSRLATMIVARLMKHGKKSTAQRILSDAFQLISQRSNGADPLEVFETAVRNATPLVEVRARRVGGATYQVPMEVRQERGTAMALRWLVNFSRTRNGRSMAQKLAGELIDAANEAGNTVRKREETHKMAEANKAFAHYRY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, organellar chromatophore.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, organellar chromatophore.
Protein: PVHE_TALVA
Sequence: MSVLNIAVSRCSPTVAFCSLVILCILFKVLTRVREDRKIRSLGKYGHQIQSKLPLGIGFLYSMVKAVRAQKNFEFWRDNIFGASGRWTVETRIMNERTIFTADPGNIKAMLATQFSDYGKGAAFHAMWKDFLGNSIFATDGERWSASRKLIRPQFTRDRLSDLQCFEAHMQTLFRVLDAGGSPLDSKHAEETPMSQGKAIDIRDLLYRFTFDVSTDFLLGQDVQSLTTPRQEFAHAFDEVQRMQTIFVRSRHFSKFMSKKSFRDSLKVMNGFIHKHVRRALSLSPQETQQKSQSGSKYTFLEAIAGFTRDPTMLRDQIVGVLLAGRDTTAATLSWALYELSRHPEAVDALRREILQTVGSDAPTYDQLKNMPYLKAVLNETLRIYPAVPYNVRIALEDTTLPHGGGPDGSEPIAVLKNTKIAYSTLILHRRRDLYPATSEKFADPAIFSPDRWLHWHPSAHDYIPFSAGPRLCTGQQFALMEMSYVLCRLFQRFERVESHMQHIDGGNPTLKADIILSPGDGVWVSFHEPKQIDSNQLL
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of varicidin A, an antifungal natural product containing a cis-octahydrodecalin core (PubMed:30609896).  The PKS module of pvhA together with the enoylreductase pvhC catalyze the formation of the polyketide unit which is then conjugated to L-isoleucine by the condensation domain of the NRPS module (PubMed:30609896).  Activity of the Dieckmann cyclase domain (RED) of pvhA results in release of an acyclic tetramate (PubMed:30609896).  The cytochrome P450 monooxygenase pvhE then catalyzes the oxidation of the C21 methyl group to a to carboxylate group (PubMed:30609896).  The methyltransferase pvhD then further methylates the pvhE product (PubMed:30609896).  The Diels-Alderase pvhB is able to catalyzes Diels-Alder cycloaddition using both pvhE and pvhD products as substrates to form the decalin ring, yielding varicidin B and A, respectively (PubMed:30609896).
What are the official names of this protein?
Cytochrome P450 monooxygenase pvhE, Varicidin biosynthesis cluster protein E.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RSIW_GEOKA
Sequence: MECPKEIVLLMHSYFDGDLQPEGEQQLKEHLRSCAACAAHFHELKKTVAFLQYAAHVAAPPSFAAKVMEAMPKERKTARLRRFLHRHPLLTAASLFLALTLGSLASSWGERGAFSVSADEHVIIRDHTVIVPKGETVKGDIVVRNGSIRIEGTVDGDVTVIHGKKYMASAGQVTGEVEEINQVFEWIWYNIKERFNRALQSIE
What is the function of this protein?
Is the anti-sigma factor for SigW.  The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation (By similarity).
What are the official names of this protein?
Anti-sigma-W factor RsiW.
What is the protein family that this protein belongs to?
Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Note=Site-2 clipped RsiW is released from the membrane to the cytoplasm.
Protein: EIF3F_MAGO7
Sequence: MAVDHDDFLHLSKPLAPSAVGFNANVAPLTVTIQPQAILSILDHAVRRDIRDTQATRVIGALVGVRSEDGTDVEVRSTFAIPHTENEDQVEVDVEYQKNMLALTLKASPRESLLGWYTTSHELNSFSALIQNFFASPETGTFPHPAVHLTMSTDPGADIEPRCYISAPAAVSPDRAAESCFFIQVPHRTPPTNESDRAALEAIAAGKDDEARTAPVLSDVEALARSLEQTIDMLDRTSEYVGAVLDEEREPSHALGQYLMNNLSLAPKVDSVSIEHDFNNHIQDVLMVSYLTNTIRTQVDLAQRLALANLTDKDEKKEGEDGKAERGGGGRGGRGGKRGGGRGGGQQREPREPREPRESREPREPRESGE
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit F, eIF3f.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit F family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLNA_VITSX
Sequence: TLSGPVSDPAKNDGGFEVIKKHKEHIAAYGEGNERHETADINTFLWGVANR
What are the official names of this protein?
Glutamine synthetase, Glutamate--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPH_OLEA2
Sequence: MHVKRAATAGFCMGVGLALKKLDRELDNNAKDIATLGPIIHNPQVLRRYEQKGVRCYTDPAEARSGQRVVIRAHGIPEETESALAAAGVDLVDATCPKVKRAQLGIARQREKGRTLLLFGEHDHPEVQGLLSYAGEGAVVFGSLEELQNGPLEDDRHYFLAAQTTQDKHAFTSVIEWVRRRFGDHVPVLDTICDATRERQDEAIAIARSVDVMVVVGGFASGNTRRLAEVAQAQGVPTYHVETPDQLPLDAIRGYGAAGLTAGASTPKSIIDETQKLLESL
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: DF262_ARATH
Sequence: MEKTSLKLIFLFSLTVIAFCSSLGDAREMVKAEVNCIGGKCPEGKKNCNCMPPIAHVMDDIRPCNTDGDCYKFCPRECELGTCYCRCDYGCTCTC
What are the official names of this protein?
Putative defensin-like protein 262.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: LANNU_STRUB
Sequence: MNNEDFNLDLIKISKENNSGASPRITSKSLCTPGCKTGILMTCPLKTATCGCHFG
What is the function of this protein?
Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria.  The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores.
What are the official names of this protein?
Lantibiotic nisin-U.
What is the protein family that this protein belongs to?
Belongs to the type A lantibiotic family.
What are the subcellular locations of this protein?
Secreted.
Protein: RK14_SOLBU
Sequence: MIQPQTHLNVADNSGARELMCIRIIGASNRRYAHIGDVIVAVIKEAVPNMPLERSEVVRAVIVRTCKELKRDNGMIIRYDDNAAVVIDQEGNPKGTRIFGAIARELRELNFTKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DLTA_STRE4
Sequence: MVNDMIETIEYFAQAQPDFPVYDCLGERRSYGQLKEDSDSIAALIESLKLGEKSPVLVFGAQSYDMLASFVALTKTGHAYIPVDVHSAPERVLSIIEIAQPSLIIAIEELPVSIDAIRVVSLAEIEAAKAAKAAFTMTSPVKGDDNYYIIFTSGTTGQPKGVQISHANLLSFTNWMIEDAEFAIPERPQMLAQPPYSFDLSVMYWAPTLALGGTLFALPKEMVSDFKRLFSTIAELPIGIWTSTPSFADMAMLNDDFCQEKMPRLTHFYFDGEELTVSTARKLFERFPDARIINAYGPTEATVALSAISITKDMIETYTRLPIGYPKPDSPTYIIDEAGNALEPGQQGEIIVTGPAVSKGYLNNPEKTAEAFFTFNGMPAYHTGDLGSFTEDNVLLYGGRLDFQIKYAGYRIELEDVSQQLNQSPLVESAVAVPRYNKEHKVQNLLAYVVLKDGVREQFARDLDITKAIKASVKDHMMAYMMPSKFIYREKLPLTPNGKIDIKFLINEVNHQ
What is the function of this protein?
Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC.  In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanine--D-alanyl carrier protein ligase, DCL, D-alanine--poly(phosphoribitol) ligase subunit 1, D-alanine-activating enzyme, DAE.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. DltA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_GLOVI
Sequence: MERTFIAIKPDGVQRGLVGEILQRFERRGFKLVGLKLMQVSEALAQKHYAEHKERPFFGGLVAFITSSPVVAVVLEGKGVVATARAMMGVTNPLNSPLGTIRGDYGIDIGRNIIHGSDSLESAEREIALWFAPAELLEWQATLGSWVYE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_HELPH
Sequence: MAHKKGQGSTQNNRDSAGRRLGVKKFGSEFVRAGNIIVRQRGTKMHPGNNVGMGKDHTLYALIDGVVKFEHKDRNRKKVSVVSQNFGE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.