PharMolix/UniProtQA huggingface dataset:
Protein: UPPP_PELTS
Sequence: MTVFQALVLGIIQGLGEFLPISSSAHLVLVPWLFGWQYAGLTFDVALHLGTLISIAAFFWKEWIVLIGSALRRRGTHEARMFWYLVLATVPGAVMGYLLEEQAETVFRTPLLIGIMLIVMGIFLYWADAKKPAVKGMREISMADSLLIGLSQAFAIIPGVSRSGVTMTAGRALGLSRETAARFSFLLSTPIIVGAGLFKLKDITPGDVNTAFITGVASSALVGFISISFLLKYLTGRSFALFVWYRLVAGLAVIVLAAARQFGF
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YDEM_ECOLI
Sequence: MHVTAKPSSFQCNLKCDYCFYLEKESQFTHEKWMDDSTLKEFIKQYIAASGNQVYFTWQGGEPTLAGLDFFRKVIHYQQRYAGQKRIFNALQTNGILLNNEWCAFLKEHEFLVGISIDGPQELHDRYRRSNSGNGTFAKVIAAIERLKSYQVEFNTLTVINNVNVHYPLEVYHFLKSIGSKHMQFIELLETGTPNIDFSGHSENTFRIIDFSVPPTAYGKFMSTIFMQWVKNDVGEIFIRQFESFVSRFLGNGHTSCIFQESCKDNLVVESNGDIYECDHFVYPQYKIGNINKSELKTMNSVQLTAQKKRIPAKCQQCAYKPICNGGCPKHRITKVNNETVSYFCEGYKILFSTMVPYMNAMVELAKNRVPLYHIMDVAKQMENN
What are the official names of this protein?
Anaerobic sulfatase-maturating enzyme homolog YdeM, AnSME homolog.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.
Protein: ARGD_OCEIH
Sequence: MSSTTKVSSAVMQTYNRFPITATKGKGSFLWDDNGEKYLDYTSGIATCNLGHVPDNVQHAISNQLKDLWHCSNLYHIPSQEKLAALLTEYSCLDQVFFCNSGAEANEAAIKIAKKYAKDKGYDDRTEIITFEQSFHGRTGSTMAATAQEKIHQGFTPLTEGFRYLPFNNKESLSEIDNGKTSAVLLEVIQGEGGIHTAEKDWLKQLAAICKQADILLMIDEIQTGIGRTGSLFAYQPYGIEPDVITVAKGLGSGFPIGAMLAKQHIAASFSPGTHGSTFGGNPVAAAAGIATLKEILSDGFLENCKEGQEELFNQLKSIKEISPLIKDIRGKGYLMGIEVMNQASAWIEKLREKQILVLPAGEKVVRILPPLTTTKEELQICIQALKEVALELGGNTNG
What are the official names of this protein?
Acetylornithine aminotransferase, ACOAT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DADA_SERP5
Sequence: MRVVILGSGVVGVASAWYLAKAGHEVTVIDRQPGPAMETSAANAGQISPGYAAPWAAPGVPLKAVKWMFQRHAPLAVRLDGSSFQLSWMWQMLKNCNTEHYMTNKGRMVRLAEYSRDCIKALRQETGIQYEGRQGGTLQLFRTQQQFESAAKDIAVLEDAGVPYKLLEASQLASVEPALAQVAHKLTGGLQLPNDETGDCQLFTQQLAKLAQQAGVTFLYNRSVDRLLVEGDKISGVQCGGEIFKADSYVVAFGSYSTALLRDLVSIPVYPLKGYSLTIPITDESAAPFSTVLDETYKIAITRFDQRIRVGGMAEIVGFNTQLEQKRRETLEMVVRDLYPNGGRVEDATFWTGLRPMTPDGTPIVGKTSLKNLFLNTGHGTLGWTMACGSGQLLSDLISGITPAIPSDDLGVARYSAGFRSLYTGPLNDVHPAR
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: LSRK_ECO24
Sequence: MARLFTPSESKYYLMALDAGTGSIRAVIFDLEGNQIAVGQAEWRHLAVPDVPGSMEFDLNKNWQLACECMRQALHNAGIAPEYIAAVSACSMREGIVLYNNEGAPIWACANVDARAAREVSELKELHNNTFENEVYRATGQTLALSAIPRLLWLAHHRSDIYRQASTITMISDWLAYMLSGELAVDPSNAGTTGLLDLTTRDWKPALLDMAGLRADILSPVKETGTLLGVVSSQAAELCGLKAGTPVVVGGGDVQLGCLGLGVVRPAQTAVLGGTFWQQVVNLAAPVTDPEMNVRVNPHVIPGMVQAESISFFTGLTMRWFRDAFCAEEKLIAERLGIDTYTLLEEMASRVPPGSWGVMPIFSDRMRFKTWYHAAPSFINLSIDPDKCNKATLFRALEENAAIVSACNLQQIADFSNIHPSSLVFAGGGSKGKLWSQILADVSGLPVNIPVVKEATALGCAIAAGVGAGIFSSMAETGERLVRWERTHTPDPEKHELYQDSRDKWQAVYQDQLGLVDHGLTTSLWKAPGL
What is the function of this protein?
Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon.  Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position.
What are the official names of this protein?
Autoinducer-2 kinase, AI-2 kinase.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MVPB_DICDI
Sequence: MATPVQASTVIRVKPHHYIHVLDNNTNVTRVEVGPQTFTRQDHERVLNPTPLPMILIPPRQYCIIENPIIRDKEGKLVVDKFNQPKLRHGDQEIRFSQDPFPLYPGEVVIAQPVPLQVIQTNSALRLKCLRDFVEVKADKTTVSHIAGDEWLFEGPGTYYPRVEVQVVEPVRAVIIKENQALKLRARLSFVDRRDVVRQVGEEWLVRESGAYLPGVSEEIVGFIQALVLTDRIAYQLLATRSFTDSFGKVRKAGEEWIITQKDCDTYIPDVNEKVIRDIKAITLTNRQYCIVENPIDPKTGKNKLGHKELLQGDRTFFLMPGESLVKGIQNVNVLSEDEALLLSAKEEFVEKKGTTTIVHKPGDLWMIYGPCDYIPPIQVDVVERRKRIPLDVNEGIYVRDIKTGKVRSVHGSSYMLLPNEERWAKPLAPIVEELLKKSASRDQNEEHNESDRDSTKVITYRVPHNAAVQIFDYRKKEARVVFGPELVMLEPDEEFTVLSLSGKIPKRPNHIRSLALFLGPDFMTDLITVETADHARLSLKLSYNWHFKVEQDNPSKLFATSDFTGDLCKATGSLVRAAVAASTFDNFHKHSSDIIQQAVFGSTDGSSNDCLYFETNGLVITNIDVQSVEPVDQRTLDSLQKSVQLAIEITTKSQEATARQEAERLEQMARGELERQKIIDEAKNEESRSKLVQLQAQSAAVESTGQAVAEARARAEAAIIEAESEIKQARLSTRAIEIEALSEIENLKAKHIVEIQHIKSLNNLELIKAKESATIETTKFENYVEALGSDTIKSIAQAPEETKAKLLAGLGLKSFMITDGKSPLNLFDTANGLIADAQRSEVDEE
What is the function of this protein?
Unknown, though MVP-beta is required for normal vault structure.
What are the official names of this protein?
Major vault protein beta, MVP-beta.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PDE6D_DROME
Sequence: MGSDDQSAGDRIQKGFQINYMILRDADSGKIIWQENKDFSAPDQEHEARVPVKILDMRAVSREINFSTIESMENFRLDQKVLFKGRIMEEWFFEMGFVGANTTNTWQSTIEAAPESQMMPAKVLNGNVTIQTSFYDNETLITKSVVRLYYI
What are the official names of this protein?
Probable cGMP 3',5'-cyclic phosphodiesterase subunit delta, DmPrBP.
What is the protein family that this protein belongs to?
Belongs to the PDE6D/unc-119 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Expressed predominantly in the nucleus, with less intense staining in the cytoplasm.
Protein: EIF3C_ANOGA
Sequence: MSRFFAGGSDSDSDSSSDSEPVIRQQVAQFTFSDEEEDVKRVVRSKKEKRYEDLSNIIKSIRNHKKIKDMSSVLTSFEEFMRAYTKALPVVMKEENGVTPRIVVRALAELEDFVNESWDDKESRKNLSKNNNKALGTLRQKFRKYIKDFESDMKRFRAAPEDFAEEEEDDEREDEKGSDEEEEKVVVQVEPKAVSFKKEPEKAKPVKPVADSDSSDWGSDSDSDSTSSDEDAKYTSIRDRFLKKPEKGTEEIASAPSGVSGDDAFKKEKKKKTGEALSKKKKPKQDEMFDENEEEEEGWKVVNGTRSGASEQPKMFAKDAEIDTKLVVNKLNEVMAARGKKRTDRKMQIEFLRELRTVAETNNLGPAVAVKIRFNIVSAIFDYNPKVSGAMKLEHWSKLLEEIQELLKLLLAHEDVHLSESILDEYEEYDTAPFKIRGCMLTAVERLDDEFTKLLKECDPHSNEYVDRLKDEVPVTNIIEQVVTYVERLGNEMEICRIYLRKIDHLYYKFDPDVLKKRKGQLPANTITSVEEMDKLCRYIYAKDQTDRLRTRAILSHIFHHALHDNWFQARDLVLMSHLQETIHHSDPATQILYNRMMANLGLCAFRHGNIKDAHLCLVDLMMTGKPKELLAQGLVPQRQHERSLEQEKIEKQRQMPFHMHINLELLECVYLVSAMLLEIPYMAAHEFDARRRMISKTFYQQLRSSERQSLVGPPESMREHVVAAAKAMRHGDWNACANFIVNKKMNVKVWDLFYEANRVREMMIKFIKEESLRTYLFTYSNVFASISVPHLADMFKLPKSKVHSLISKMIINEELMASLDDPTETIVMHRSEPSRLQALSMQLADKVTNLVDANERIFEMKQGNFFQRGGNQGYNRDRQNYRNQNQNQNWNNNRRQDNRNRGNRGNQNRGEGREQREHHRDHHRDQREHREHQNREFREQREQMRNVEYQNKAE
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit C, eIF3c, Eukaryotic translation initiation factor 3 subunit 8.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYV_BLOPB
Sequence: MSNYIVEKIYNPKNIEEPIYKFWEYGDYFSPHGNTSQESYCIMMPPPNITGQLHLGHAFQQTIMDVLIRYQRMQGKNTLWQTGTDHAGIATQMLVEHKIYNNTGKTRHDYTRDELIKNIWAWKSQSEQFITYQMKRLGNSVDWKRQRFTMDTEMSYAVTEAFIRLYRKNLIYRGKRLVNWDCKLQTAISDLEVINKKTKGSIWYIYYKLDNATISSNSHHLIVATTRPETMLGDTAVAVHPEDTRYKNYIGQYVIAPITNRRIPIISDKNVDMFKGTGCLKITPAHDFNDYIIGKRHGLPMINIFSLNGKILKKLEVFNSSGQLTDQLYCKIPQIFHNLDSDNARKKIISECNALKLLHNIEPHDLTIPYSDRTGTIIEPMLTDQWYIRVKHLTQHAIDAVNLNIINFVPKQYKNMYFSWMNNLQDWCISRQIWWGHKIPAWYDDNNTIYVGYCEKDIRIKNKLNNNVILHREKDVLDTWFSSSLWTFAALGWPKNTNLLNVFHPTNIIISGFDIIFFWIARMIMLTMHFIKNDNGSAQIPFKTVYITGLIRDELGQKMSKSKGNIIDPIDIIDGISIENLLKKRTKNMLQPQLSKHIINNTIKQFPNGIKPHGTDALRFTLVALASSGRDIHWDMQRLTGYRNFCNKLWHASRFVLMHTKNQDCGISININEKSFSLADRWIITKFHQTVQIFHKKLEIYRFDEIANILHEFIWHQFCDWYLELTKPILYHGNALELRGTRYTLITLLESLLRLTHPIIPFITEKIWQEVKTVTGNNGTTIMLQPFPKYDESVIDMKSVIDIEWIKNAVLAIRTARVNMNISYNIPLQIVFRDTSSEVKKRITENSKILCHIAQLKSIHFISKGTIYPKSMTMPLDSSELLIRIPDTFNKENEINRLKKESELINRKIETIQKLLDDNNFINQAPKSVIKDKQALLNYYELIQNKLIDQCAIMKKL
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPT_FLATR
Sequence: MESRVLSSGATAISGVPRLTKPAGRITTTTVAVAFPARLNATGGNVVWGRQLRPSLLNLDHSSPVSLVTKPVKRDVLKPCSATASDSAGDAAPVGFLAKYPFLVTGFFFFMWYFLNVIFNILNKKIYNYFPYPYFVSVIHLAVGVVYCLGSWTVGLPKRAPVDSNILKLLIPVGFCHALGHVTSNVSFAAVAVSFTHTIKALEPFFNAAASQFVLGQSIPISLWLSLAPVVIGVSMASLTELSFNWLGFISAMISNISFTYRSIYSKKAMTDMDSTNLYAYISIIALLFCIPPAVLFEGPQLLKHGFNDAIAKVGMIKFISDLFWVGMFYHLYNQIATNTLERVAPLTHAVGNVLKRVFVIGFSIIVFGNKISTQTAIGTSIAIAGVAIYSLIKARIEEEKRRMKSA
What is the function of this protein?
Mediates the export of fixed carbons from the chloroplasts into the cytosol in the form of triose phosphates.  In addition, it can also bind and transport phosphoenolpyruvate, thereby increasing the photosynthetic efficiency of C4-plants.
What are the official names of this protein?
Triose phosphate/phosphate translocator, chloroplastic, cTPT.
What is the protein family that this protein belongs to?
Belongs to the TPT transporter family. TPT (TC 2.A.7.9) subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein. Note=Located in zones of contact between the inner and outer membrane of the chloroplast.
Protein: HSLO_STRPS
Sequence: MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGRTLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATGEVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNVLLDEEDKVKIAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIYGDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYNFDEKDLEELIRDKS
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCD_PANGI
Sequence: MERWWFNSILFKKEFEHRCGLSKSTGSLGPIENTSESEDPNINDMKKNIHSWGGRDNSNYSNVDHLFGVKDIRNFISDETFLVRDSNGNSYSIYFDIENHIFEIDNGHSFQSELESSFYSYQNSSYRNNGSNSDDPHYDHYMYDTQYSWNNNINSCIDNYLQSQIFIETDIVSGSDNYSNSYIYSSICGEIAGSGIRTRTDGSDLTIRESSNDLDVTQKYRHLWVQCENCYGLNYKKSFKSKMNLCEQCGYHLKMSSSDRIELLIDPGTWDPMDEDMVSLDPIEFHSEEEPYKDRVDSYQRKTGLTEAVQTGIGQLNSIPVAIGVMDFQFMGGSMGSVVGEKITRLIEYATKKFLPLIIVCASGGARMQEGSLSLMQMAKISSALYDYQSNKKLFYVPILTSPTTGGVTASFGMLGDIIIAEPNAYIAFAGKRVIEQTLNKTVPEGSQAAEYLFQKGLFDLIVPRNPLKSVLSELFQLHAFFPLNQN
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: GLNP_BACSU
Sequence: MDFIGAYSQEHLAFLWDGFLVTLYVAFISIILSFFFGLIAGTLRYAKVPVLSQLIAVLVETIRNLPLLLIIFFTFFALPEIGIKLEITAAAITALTIFESAMLSEIIRSGLKSIDKGQIEAARSSGLSYTQTLFFIVMPQALRRMVPPIVSQFISLLKDTSLAVVIALPELIHNAQIINGQSADGSYFFPIFLLAALMYFAVNYSLSLAARRLEVRQT
What is the function of this protein?
Part of the ABC transporter complex GlnHMPQ involved in glutamine transport.  Probably responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
Probable glutamine ABC transporter permease protein GlnP.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GLND_YERPP
Sequence: MSDNHTEHSLSLTLTPTISEQPALPSTYLDSDIHCPILKQRLDAFQRWQAEAFNSGTSAEVLIAARSDYIDHLLQRLWTFYGFDKVPETALVAVGGYGRGELHPLSDIDVLVLSKQRLNDEQAQRVGQLITLLWDLKLEVGHSVRTLEECLLEGLADLTIATNMIESRLICGDVALFLQMQKHIFSDSFWPSPQFFHAKVVEQQERHKRYHGTSYNLEPDIKSSPGGLRDIHTLLWVARRHFGATSLSEMVDFGFLTNAERNELNESQSFLWRIRFALHLVLTRYDNRLLFDRQLSVAQLLRYEGEGNEPVEHMMKDFYRMTRRVSELNNMLLQLFDEAILALDANEKPRPLDEEFQLRGDLIDLRDENLFVRQPEAIMRMFYLMVRNQDIKGIYSTTVRRLRHARRHLKAPLCHIPEARKLFMAILRHPGAVSRALLPMHRHSVLWAYMPQWGSIVGQMQFDLFHAYTVDEHTIRVLLKIESFADEDTRPRHPLCVELYPRLPQPELLLLAALFHDIAKGRGGDHSILGAHDAVEFAEQHGLNSRESQLVAWLVRCHLLMSVTAQRRDIQDPAVIQQFSAEVQSETRLRYLVSLTVADICATNENLWNSWKQSLLRELYFATEKQLRRGMQNSPDLRERVRHHRLQALALLRMDNIDEEALHRIWSRCRADYFLRHSPNQLAWHARHLLEHDSTKPLVLVSRQATRGGTEIFIWSPDRPSLFAAVVGELDRRNLSVHDAQIFTNRDGMAMDTFIVLEPDGSPLAQDRHPIISHALQQAINRSDYQHPPRVRRLSPKLRHFSVPTEANFLPTHNERRTYLELIALDQPGLLARVGKIFADLGLSLHSARITTIGERVEDLFVLADKDRRALSLETRRELAQRLADTLNPNDKL
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: MFA1_YEAST
Sequence: MQPSTATAAPKEKTSSEKKDNYIIKGVFWDPACVIA
What is the function of this protein?
The active factor is excreted into the culture medium by haploid cells of the A mating type and acts on cells of the opposite mating type (type alpha).  It mediates the conjugation process between the two types by inhibiting the initiation of DNA synthesis in type alpha cells and synchronizing them with type A.
What are the official names of this protein?
Mating hormone A-factor 1.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: SOG2_YEAST
Sequence: MVATSSKRTLDPKEEHLPADKTSTNSSNTIISELATQEKSSSSGTTLKLIALNIKSISDEDVGYIQNVERLSLRKNHLTSLPASFKRLSRLQYLDLHNNNFKEIPYILTQCPQLEILDLSSNEIEALPDEISSFWQDNIRVLSLKDNNVTSIRNLKSITKLNKLSILDLEDNKIPKEELDQVQSYTPFHTGIPKEEYWAIAISRYLKDHPNLPTPEPKISRAAKRMGFINTNLSNGAMNENNIISLAPSANTTISASTAMVSSNQTSATSFSGTVNAESEQSGAVNGTELYNHTKYNDYFKRLSILPEESMSNGHQKISHAELVVSCRKLLFSFTECQQAIRKIASFCKEKAVAVNVVSLLYSVRSHTDNLVEVLQQTENEDESHDQALIKLCLTIITNFKQIITLLRKNFEIFFKEDDLCFIRMFYMTLMCAYMEMYNAWSFIKEDDQVSGSASKAPKKHSFSRHETSSSSITSGGGPAASTTSTHCSGNIKLLPKTRSTRTPSASALLSNSNILTGDTTAVPLLSPNLNGAHTHGPILGHQNAISNGSSQTNMNEVKTTSDTIPRQQLLQHNKSISDSKKESQAHEPKQHPVMTSSIINASNSNNVSNVNITPPPMNGGGAANSSANVVETNIDIQLYQTLSTVVKMVSVVYNQLTSEISKIAIASTMGKQILTDSLAPKIRDLTETCRQAMDLSKQLNERLNVLIPNDSNSEKYLTSLEKLKTWEIMNSFLKVIISILANTKIVMSDVPNLNELRPNLANLAKITKDVTVILDLSSYKAVSVSANSPE
What is the function of this protein?
Required for proper cell morphogenesis and cell separation after mitosis.  Functions in the RAM (regulation of ACE2 activity and cellular morphogenesis) signaling network and is required for proper ACE2 localization and CBK1 kinase activity.
What are the official names of this protein?
Leucine-rich repeat-containing protein SOG2.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to cortical sites of growth during both budding and mating pheromone response. Localized prominently to incipient bud sites and small buds and weakly to the cortex and bud necks of large budded cells. Also localized to the growing tips of mating projections.
Protein: TRUB_BACLD
Sequence: MYNGVLLLHKPVGMTSHDCVMKIRKLLKTKKVGHTGTLDPEVSGVLPICVGRATKIVEYLTEKSKTYDAEVTLGCSTETEDQTGEVTEKKPVLAPPDEQTVQSVLRSLEGTIEQVPPMYSAVKVGGKKLYEYARAGIEVERPKRTITIHHIELTSEIRHEGDKARFRFVVTCSKGTYVRTLAVTIGEKLGYPAHMSNLVRTASGPFTLDECLTFEDVEGLIADGTLSEKLVPIERALDHLPKWIISDTLAKKVENGAVLETPGSFSHLTSEDRIAVFTEAGRCTAVYYPHPTKTGLLKPAKVLVQKSEQ
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: MFTC_MYCS2
Sequence: MTSVQPVPRLVEQFERGLDAPICLTWELTYACNLACVHCLSSSGKRDPRELSTQQCKDIIDELERMQVFYVNIGGGEPTVRSDFWELVDYATAHHVGVKFSTNGVRITPEVAAKLAASDYVDVQISLDGANAEVNDAVRGKGSFDMAVRALENLSNAGFTDAKISVVVTRQNVDQLDEFAALAARYGATLRITRLRPSGRGADVWDDLHPTAEQQRQLYDWLVAKGDRVLTGDSFFHLSGLGAPGALAGLNLCGAGRVVCLIDPVGDVYACPFAIHDKFLAGNILSDGGFQNVWQHSELFRELREPQSAGACASCGHFDACRGGCMAAKFFTGLPLDGPDPECVEGWGAPALEKERVKPKPSGDHSRGTKQGPVALKLLTKPPARFCNESPV
What is the function of this protein?
Radical S-adenosylmethionine (SAM) enzyme responsible for the first step of the biosynthesis of the enzyme cofactor mycofactocin (MFT).  Catalyzes two reactions at the C-terminus of the mycofactocin precursor (the MftA peptide).  The first one is the oxidative decarboxylation of the C-terminal L-tyrosine of MftA, forming an unsaturated tyramine moiety (PubMed:27158836).  The second reaction is the cross-linking of the tyramine with the penultimate L-valine residue, forming a five-membered lactam ring (By similarity).  Its activity requires the presence of the MftB chaperone (PubMed:27158836).  Is required for the in vivo ethanol assimilation in M. smegmatis (PubMed:31113891).
What are the official names of this protein?
Mycofactocin maturase MftC, [Mycofactocin precursor peptide]-pyrrolidinone derivative synthase, [Mycofactocin precursor peptide]-tyrosine decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MftC family.
Protein: TREY_MYCTU
Sequence: MAFPVISTYRVQMRGRSNGFGFTFADAENLLDYLDDLGVSHLYLSPILTAVGGSTHGYDVTDPTTVSPELGGSDGLARLSAAARSRGMGLIVDIVPSHVGVGKPEQNAWWWDVLKFGRSSAYAEFFDIDWELGDGRIILPLLGSDSDVANLRVDGDLLRLGDLALPVAPGSGDGTGPAVHDRQHYRLVGWRHGLCGYRRFFSITSLAGLRQEDRAVFDASHAEVARWFTEGLVDGVRVDHLDGLSDPSGYLAQLRELLGPNAWIVVEKILAVDEALEPTLPVDGSTGYDVLREIGGVLVDPQGESPLTALVESAGVDYQEMPAMLADLKVHAAVHTLASELRRLRRCIAAAAGADHPLLPAAVAALLRHIGRYRCDYPGQAAVLPCALAETHSTTPQLAPGLQLIAAAVARGGEPAVRLQQLCGAVSAKAVEDCMFYRDARLVSLNEVGGEPRRFGVGAAEFHHRAATRARLWPRSMTTLSTHDTKRGEDVRARIGVLSQVPWLWAKFIGHAQAIAPAPDAVTGQFLWQNVFGVWPVSGEVSAALRGRLHTYAEKAIREAAWHTSWHNPNRAFEDDVHGWLDLVLDGPLASELTGLVAHLNSHAESDALAAKLLALTVPGVPDVYQGSELWDDSLVDPDNRRPVDYGTRRVALKALQHPKIRVLAAALRLRRTHPESFLGGAYHPVFAAGPAADHVVAFRRGDDILVAVTRWTVRLQQTGWDHTVLPLPDGSWTDALTGFTASGHTPAVELFADLPVVLLVRDNA
What is the function of this protein?
Catalyzes the conversion of maltooligosaccharide into the non-reducing saccharide, maltooligosyl trehalose (alpha-maltooligosyl alpha-D-glucoside) by intramolecular transglycosylation.
What are the official names of this protein?
Putative maltooligosyl trehalose synthase, (1,4)-alpha-D-glucan 1-alpha-D-glucosylmutase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: SYLM_MOUSE
Sequence: MASTCQRLSFYVSPLKRQLVSRPPVILWERLIPGCSRSIYSATGKWTKEYTLQTRKDVEKWWHQQIKEQASRVSEEDKLKPKFYLLSMFPYPSGKLHMGHVRVYTLSDTIARFQKMRGMQVINPMGWDAFGLPAENAAIERNLHPESWTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVNEYGCSWRSGAKVEKKYLRQWFIKTTAYAKAMQDALADLPEWYGIKGMQAHWIGDCVGCHLDFTLKVDGEDTGEKLTAYTATPEAIYGISHVAISPSHGLLHGCSSVKKALQKALVPGRDCLTPVMAVSMLTLQEVPIVIMANPDLEGSLDSKIGIPSTSSEDTRLAQALGLPYSEVIEASPDGTERLSGSAEFTGMTRQDAFVALTRKARGMRVGGHVTSNKLKDWLISRQRYWGTPIPIVHCPACGPVPVPLQDLPVILPSIASLTGRGGSPLATALEWVNCSCPRCKGSAKRETDTMDTFVDSAWYYFRYTDPHNTQSPFGSALADFWMPVDLYIGGKEHAVMHLFYARFLSHFCHDQKMVKHREPFHKLLAQGLIKGQTFRLPSGQCLKKEDIDFTGPAPVCAKTKEKLEVTWEKMSKSKHNGVDPEEIVAQYGIDTIRLYILFAAPPEKDILWDVKTDALPGVLRWQQRLWSLTTRFIEARTSGTVPQPQLLNSKEKTKAQNLWEYKNAVIAQVTTHFTEDFALNSVVSQLMGLSSALSQASQRVVLHSPEFEDALCALLVMAAPLAPHVTSELWAGLTLVPSKLCDHYAWDSGVMLQAWPTVDSQFLQKPDMVQMAVLINNKACGKIPVPQHVAQDQDKVHELVLQSELGMKLLQGRSIKKAFLSPRTALINFLVQE
What are the official names of this protein?
Probable leucine--tRNA ligase, mitochondrial, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RLP53_ARATH
Sequence: MEGFWNSKSIIRITLSFIFLFICHFLDVLAAPTRNLCRPEQRDALLAFKNEFEIGKPSPDHCKIYGIESPRKTDSWGNNSDCCNWEGVTCNAKSGEVIELDLSCSSLHGRFHSNSSIRNLHFLTTLDLSFNDFKGQITSSIENLSHLTYLDLSSNHFSGQILNSIGNLSRLTYLNLFDNQFSGQAPSSICNLSHLTFLDLSYNRFFGQFPSSIGGLSHLTTLSLFSNKFSGQIPSSIGNLSNLTTLDLSNNNFSGQIPSFIGNLSQLTFLGLFSNNFVGEIPSSFGNLNQLTRLYVDDNKLSGNFPNVLLNLTGLSLLSLSNNKFTGTLPPNITSLSNLMDFDASDNAFTGTFPSFLFTIPSLTYIRLNGNQLKGTLEFGNISSPSNLYELDIGNNNFIGPIPSSISKLVKLFRLDISHLNTQGPVDFSIFSHLKSLLDLNISHLNTTTRIDLNYFLSYFKRLLLLDLSGNHVSATNKSSVSDPPSQLIQSLYLSGCGITEFPEFVRTQHELGFLDISNNKIKGQVPDWLWRLPILYYVNLSNNTLIGFQRPSKPEPSLLYLLGSNNNFIGKIPSFICGLRSLNTLDLSDNNFNGSIPRCMGHLKSTLSVLNLRQNHLSGGLPKQIFEILRSLDVGHNQLVGKLPRSLSFFSTLEVLNVESNRINDTFPFWLSSLPKLQVLVLRSNAFHGPIHEATFPELRIIDISHNRFNGTLPTEYFVKWSAMSSLGKNEDQSNEKYMGSGLYYQDSMVLMNKGVAMELVRILTIYTAVDFSGNRFEGEIPKSIGLLKELLVLSLSNNAFSGHMPSSMGNLTALESLDVSKNKLTGEIPQELGDLSFLAYMNFSHNQLAGLVPGGQQFLTQNCSAFEDNLGLFGSSLEEVCRDIHTPASHQQFETPETEEEDEDLISWIAAAIGFGPGIAFGLMFGYILVSYKPEWFMNPFDRNNRRQKRHKTTH
What are the official names of this protein?
Receptor-like protein 53, AtRLP53.
What is the protein family that this protein belongs to?
Belongs to the RLP family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: GDS1_YEAST
Sequence: MDYEEILFGLQPILNASSIKDVPMNDVYLGSYLAVMDQLAVSLREPSNRDIVGKTGLLLNLVRVLEQALDICFHDTSISINDKIAFYEISSEVIRCIANAIIDNDDNREILLDSGGKKLLNYYIGGVLQLDEISSDKSEDSLVDKLQMRSVVLLRNFCIGNLKYTENLAPFIRGPLFVLLKTTQYSYLSSPEKVVLGSDLLNDILKVNYSNVQISDLFFLSQYIKKISSNVQNKELQAMEDGAVEAYSNTETQKFAGQGNQEYIEKEEEDDEEDVNCELLLNLSTCLETIVAKDETINFTNEEQLVLSMQKNLILSLVCLESKTFNNKLIVMRRLISCAGNISANLTNSNKREQSLCIETIKSSASSYALAAALMILCNSVASKSDAVALLKLISLSELIQVGSLLQDPLQYQGFLDLLRKLLNLENTMWLDIKDLFTLFQIMRRCHEQTKYYNNLRSLLTNLLNKTLTVLPSSKIHNSISSDPTIISFIAEHGTLTSCIAMDKLLVSKKALPKEAITSLWDSIFKFQNLGQAEQLSISDLFHITKTVGIYLKDSSVTADVNPIENILFKDYIQKLTLILETILSFKENKDKGSESCFNNGKFIAGIILNIVKNTKCLTPEEQNLEALAKSFF
What is the function of this protein?
Probably acts as a GEF (guanine nucleotide exchange factor) for the Rho family of small GTP-binding proteins (G proteins) that stimulates the dissociation of GDP to enable subsequent binding of GTP (By similarity).  May also chaperone the processing and/or trafficking of small GTPases independently of GEF activity (By similarity).  Involved in the control of polarized cell growth via CDC42-mediated signaling (PubMed:8754839).  Involved in the control of cell-wall organization via RHO1-mediated signaling (PubMed:8754839, PubMed:8754840).  May also function via RHO2 and RHO4 (PubMed:8754839).
What are the official names of this protein?
GTPase-GDP dissociation stimulator BEM4, Bud emergence protein 4.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.