PharMolix/UniProtQA huggingface dataset:
Protein: IF2_BACFN
Sequence: MTIRLNKVTRDLNVGIATVVEFLQKKGYTVEANPNTKITEEQYAMLVKEFSTDKNLRLESERFIQERQNKDRNKASVSIDGYDKKEPEKTVADDVIKTVIPEDVRPKFKPVGKIDLDKLNRKVEKEPVKEEPKPQPVAAEEKKVAEEVKPVVNEVKKEEVTVTPATSEPKPVKEEPKPVVVEKPVETEKKVVEEVKKEEPKVVVSPEKTEKKEEKPVAEAPVTPVEKEEEGVFKIRPTEFVSKINVIGQIDLAALNQSTRPKKKSKEEKRKEREEKEKLRQDQKKQMKEAIIKEIRKEDSKQAKVVGKENLDPNGKKKRNRINNNKEKVDVNNVASNFAHPTPNSERTNNNRGGNQQGGGGQNRNRNNNNKDRFKKPVVKQEVSEEDVAKQVKETLARLTSKGKNKGAKYRKEKRDMASNRMQELEDQEMAESKVLKLTEFVTANELASMMNVSVNQVIGTCMSIGMMVSINQRLDAETINLVAEEFGFKTEYVSAEVAQAIVEEEDAPEDLEHRAPIVTVMGHVDHGKTSLLDYIRKANVIAGEAGGITQHIGAYHVTLEDGRKITFLDTPGHEAFTAMRARGAKVTDIAIIIVAADDDVMPQTKEAINHAAAAGVPIVFAINKIDKPHANPEKIKETLAQMNYLVEEWGGKYQSQDISAKKGLGVPELMEKVLLEAEMLDLKANPNRNATGSIIESTLDKGRGYVATVLVSNGTLKVGDIVLAGTSYGRVKAMFNERNQRVAQAGPSEPVLILGLNGAPAAGDTFHVIETDQEAREIANKREQLQREQGLRTQKLLTLDEVGRRIALGNFQELNVIVKGDVDGSIEALSDSLIKLSTEQIQVNVIHKAVGQISESDVTLAAASDAIIIGFQVRPSASARKFAEQEGVDIRLYSVIYAAIEEVKAAMEGMLAPEVKEVVTATIEVREVFHITKVGTVAGAVVKEGKVKRSDKARLIRDGIVIFSGSINALKRFKDDVKEVGTNFECGISLVNYNDLKVGDMIETYEEVEVKQTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XGPT_NITWN
Sequence: MSAHKTPDKAFPVSWDQFHRDCRALSWRLNETGPFHAVVAITRGGLVPAAIVARELGVRVIDTVCIASYDHLHKSELKVLKGISDMTVKLGGGSGRNLLVVDDLVDTGATARVVRGMIPDAHFATVYAKPLGKPLVDTFITEVSQDTWIYFPWDLDLAFAPPLRDGAA
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi.  To a lesser extent, also acts on hypoxanthine.
What are the official names of this protein?
Xanthine-guanine phosphoribosyltransferase, XGPRT, Xanthine phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: L_PIV5W
Sequence: MAGSREILLPEVHLNSPIVKHKLYYYILLGNLPNEIDLDDLGPLHNQNWNQIAHEESNLAQRLVNVRNFLITHIPDLRKGHWQEYVNVILWPRILKLLPDFKINDQLPLLKNWDKLVKESCSVINAGTSQCIQNLSYGLTGRGNLFTRSRELSGDRRDIDLKTVVAAWHDSDWKRISDFWIMIKFQMRQLIVRQTDHNDPDLITYIENREGIIIITPELVALFNTENHTLTYMTFEIVLMVSDMYEGRHNILSLCTVSTYLNPLKKRITYLLSLVDNLAFQIGDAVYNIIALLESFVYAQLQMSDPIPELRGQFHAFVCSEILDALRGTNSFTQDELRTVTTNLISPFQDLTPDLTAELLCIMRLWGHPMLTASQAAGKVRESMCAGKVLDFPTIMKTLAFFHTILINGYRRKHHGVWPPLNLPGNASKGLTELMNDNTEISYEFTLKHWKEVSLIKFKKCFDADAGEELSIFMKDKAISAPKQDWMSVFRRSLIKQRHQHHQVPLPNPFNRRLLLNFLGDDKFDPSVELQYVTSGEYLHDDTFCASYSLKEKEIKPDGRIFAKLTKRMRSCQVIAESLLANHAGLLMKENGVVMNQLSLTKSLLTMSQIGIISEKARKSTRDNINQPGFQNIQRNKSHHSKQVNQRDPSDDFELAASFLTTDLKKYCLQWRYQTIIPFAQSLNRMYGYPHLFEWIHLRLMRSTLYVGDPFNPPADTSQFDLDKVINGDIFIVSPRGGIEGLCQKAWTMISIAVIILSATESGTRVMSMVQGDNQAIAVTTRVPRSLPTLEKKTIAFRSCNLFFERLKCNNFGLGHHLKEQETIISSHFFVYSKRIFYQGRILTQALKNASKLCLTADVLGECTQSSCSNLATTVMRLTENGVEKDICFYLNIYMTIKQLSYDIIFPQVSIPGDQITLEYINNPHLVSRLALLPSQLGGLNYLSCSRLFNRNIGDPVVSAVADLKRLIKSGCMDYWILYNLLGRKPGNGSWATLAADPYSINIEYQYPPTTALKRHTQQALMELSTNPMLRGIFSDNAQAEENNLARFLLDREVIFPRVAHIIIEQTSVGRRKQIQGYLDSTRSIMRKSLEIKPLSNRKLNEILDYNINYLAYNLALLKNAIEPPTYLKAMTLETCSIDIARNLRKLSWAPLLGGRNLEGLETPDPIEITAGALIVGSGYCEQCAAGDNRFTWFFLPSGIEIGGDPRDNPPIRVPYIGSRTDERRVASMAYIRGASSSLKAVLRLAGVYIWAFGDTLENWIDALDLSHTRVNITLEQLQSLTPLPTSANLTHRLDDGTTTLKFTPASSYTFSSFTHISNDEQYLTINDKTADSNIIYQQLMITGLGILETWNNPPVNRTFEESTLHLHTGASCCVRPVDSCIISEALTVKPHITVPYSNKFVFDEDPLSEYETAKLESLSFQAQLGNIDAVDMTGKLTLLSQFTARQIINAITGLDESVSLTNDAIVASDYVSNWISECMYTKLDELFMYCGWELLLELSYQMYYLRVVGWSNIVDYSYMILRRIPGAALNNLASTLSHPKLFRRAINLDIVAPLNAPHFASLDYIKMSVDAILWGCKRVINVLSNGGDLELVVTSEDSLILSDRSMNLIARKLTLLSLIHHNGLELPKIKGFSPDEKCFALTEFLRKVVNSGLSSIENLSNFMYNVENPRLAAFASNNYYLTRKLLNSIRDTESGQVAVTSYYESLEYIDSLKLTPHVPGTSCIEDDSLCTNDYIIWIIESNANLEKYPIPNSPEDDSNFHNFKLNAPSHHTLRPLGLSSTAWYKGISCCRYLERLKLPQGDHLYIAEGSGASMTIIEYLFPGRKIYYNSLFSSGDNPPQRNYAPMPTQFIESVPYKLWQAHTDQYPEIFEDFIPLWNGNATMTDIGMTACVEFIINRVGPRTCSLVHVDLESSASLNQQCLSKPIINAIITATTVLCPHGVLILKYSWLPFTRFSTLITFLWCYFERITVLRSTYSDPANHEVYLICILANNFAFQTVSQATGMAMTLTDQGFTLISPERINQYWDGHLKQERIVAEAIDKVVLGENALFNSSDNELILKCGGTPNARNLIDIEPVATFIEFEQLICTMLTTHLKEIIDITRSGTQDYESLLLTPYNLGLLGKISTIVRLLTERILNHTIRNWLILPPSLRMIVKQDLEFGIFRITSILNSDRFLKLSPNRKYLIAQLTAGYIRKLIEGDCNIDLTRPIQKQIWKALGCVVYCHDPMDQRESTEFIDININEEIDRGIDGEEI
What is the function of this protein?
RNA-directed RNA polymerase that catalyzes the replication of viral genomic RNA.  The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N).  The replicase mode is dependent on intracellular N protein concentration.  In this mode, the polymerase replicates the whole viral genome without recognizing transcriptional signals, and the replicated genome is not caped or polyadenylated.
What are the official names of this protein?
RNA-directed RNA polymerase L, Protein L, Large structural protein, Replicase, Transcriptase.
What is the protein family that this protein belongs to?
Belongs to the paramyxovirus L protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: FETP_ECO45
Sequence: MSRTIFCTFLQREAEGQDFQLYPGELGKRIYNEISKEAWAQWQHKQTMLINEKKLNMMNAEHRKLLEQEMVNFLFEGKEVHIEGYTPEDKK
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: GATE_PYRHO
Sequence: MMQMSDKFNYEELGLKVGLEIHRQLDTKKLFSPVPTKFSDEVDFTFQRRLRPTMSELGEVDPAALEEFKKGRVFIYEGNYQLTDLVYMDEEPPRGPDKEALEVALQIAYLLNAKPVDEVYYMRKIVIDGSNVSGFQRTAIIATDGKVETPWGTVGIPTICLEEDAARIIERKEKEVIYRLDRLGVPLVEISTTPDIHHPEQAKVVAKFIGDALRATRKVKRGLGTIRQDLNVSIKGGARIEIKGVQELDMIPLIIEREVERQLNLLKIRDELQRRGVRPEDIKEEFYDVTDVFTNTKSKIIARAIKKGGKVLAIKLPKFRGLIGREIQPGRRLGTEFADRARKYVPGIFHIDELPNYGITQEEVNEVIKRLGLGEEDAFVLVAAEEERAKNALREVIKRAKEAIIGVPEETRRALPDGNTEYMRPLPGKARMYPETDIPPIRIPDELKRKIKENLPELPQVKVEKYVREYKLDRSLAQTLVDDERDELFEELVQMGVKPSLAASILVVVLKGLRKEVPIENISDEHIKEAFSLYLEGKIAKEAFEEIFKEIARNPNKTARQIAEEKGLTLLSEDEVRKIIDEVIEQNIEVVKNKGMGAMGLIMGRVMAKVRGKADGKLVSQIVKKRLQEIVGGGV
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).  The GatDE system is specific for glutamate and does not act on aspartate.
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit E, Glu-ADT subunit E.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatE subfamily.
Protein: KC1G2_HUMAN
Sequence: MDFDKKGGKGETEEGRRMSKAGGGRSSHGIRSSGTSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSATEGVPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGTKRQHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRSGFVFDYEYDWAGKPLPTPIGTVHTDLPSQPQLRDKTQPHSKNQALNSTNGELNADDPTAGHSNAPITAPAEVEVADETKCCCFFKRRKRKSLQRHK
What is the function of this protein?
Serine/threonine-protein kinase.  Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates.  It can phosphorylate a large number of proteins.  Participates in Wnt signaling.  Phosphorylates COL4A3BP/CERT, MTA1 and SMAD3.  Involved in brain development and vesicular trafficking and neurotransmitter releasing from small synaptic vesicles.  Regulates fast synaptic transmission mediated by glutamate.  SMAD3 phosphorylation promotes its ligand-dependent ubiquitination and subsequent proteasome degradation, thus inhibiting SMAD3-mediated TGF-beta responses.  Hyperphosphorylation of the serine-repeat motif of COL4A3BP/CERT leads to its inactivation by dissociation from the Golgi complex, thus down-regulating ER-to-Golgi transport of ceramide and sphingomyelin synthesis.  Triggers PER1 proteasomal degradation probably through phosphorylation.
What are the official names of this protein?
Casein kinase I isoform gamma-2, CKI-gamma 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
Protein: QUEF_ACIF2
Sequence: MPSQPSRELERFSNPHPERDYVVHMDLPEFTCLCPLTGQPDFAHFMLDFIPDQHNVELKSLKLYLWSFRDEGAFHEAMTNRIADDLIGLINPRYLRLLGRWYVRGGITTDVLIEHRQPGWQNPDILGQLPTVRWAQHQPGH
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_EHRCR
Sequence: MANVVVTGEQLDKSIREVVRILEDAVGCTAGPKGLTVAIGKSYGAPEVTKDGYKVIKSIKPEDPLALAIANIITQSASQCNDKVGDGTTTCSILTAKVIEEVSKAKAAGADIVCIKEGVLKAKEAVLEALMSMKREVLSEEEIAQVATISANGDKNIGSKIAQCVQEVGKDGVITVEESKGFKELDVEKTDGMQFDRGYLSPYFVTNSEKMLVEFENPYILLTEKKLNIIQPILPILENVARSGRPLLIIAEDVEGEALSTLVLNKLRGGLHVAAVKAPGFGDRRKDMLGDIAILTGAKHVISDDLAIKMEDLTLAELGTAKNIRITKDTTTIIGSVDNSSANVQSRINQIKMQIEASTSDYDKEKLRERLAKLSGGVAVLKVGGSSEVEVKERKDRVEDALHATRAAVEEGVVPGGGAALLYTLSVLENLKSKNDDEQLGINIVKRALQAPIKRIIKNSGSENAPCVIAHLLKQNDKELIFNVDTMNFANAFTSGVIDPLKVVRIAFDFAVSLAAVFMTLNAIVVDVPSKDDANAGAGGMGGMGGMGGF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAK_HALMA
Sequence: MASNKILGIDLGTTNSAFAVMEGGDPEIIVNGEGERTTPSVVAFDDGERLVGKPAKNQAVKNPDETIQSIKRHMGEDDYSVELDGEEYTPEQVSAMILQKIKHDAEEYLGDEIEKAVITVPAYFNDRQRQATKDAGEIAGFEVERIVNEPTAAAMAYGLDDESDQTVLVYDLGGGTFDVSILDLGGGVYEVVATNGDNDLGGDDWDHAIIDYLADEFEAEHGIDLRDDRQALQRLTEAAEEAKIELSSRKETRINLPFIATTDDGPLDLEQKITRAKFESLTEDLIERTVGPTEQALADADYTKSDIDEVILVGGSTRMPQVQDQVEEMTGQEPKKNVNPDEAVALGAAIQAGVLSGDVDDIVLLDVTPLSLGVEVKGGLFERLIDKNTTIPTEESKIFTTAQDNQTQVQIRVFQGEREIAEENELLGAFALSGIPPAPAGTPQIEVSFNIDENGIVNVEAEDKGSGNKEDITIEGGAGLSDDQIEEMQQEAEQHAEEDEQRRERIEARNEAEASVRRAETLLDENEEEIDEDLQSDIEAKIEDVEEVLEDEDATKEDYEAVTETLSEELQEIGKQMYQDQAQQAAGGAAGAGPGGAAGPGGAAGPGGAAGGAAEQGEEYVDADFEDVEESDEDE
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: LON_ACIB3
Sequence: MSELIMNEKTDLEPQVPSVLPLLALRDVVVYPHMQIALFVGREKSINAVDVARNSDNLVFVVAQKDSLTEEIDHDNLYQYGTVAKIVQVVNHENDENCIKVLIEGLHRSKLKKIIDEDSYLTAEHELSPMTINVDKATQETRLQELRNLFAQYAEAKLRNARELVAAANKIEDLLQLMFFVATRVPLNIEIKQKFLEYDEFEAHLQELMNYLMNQSAEQQIEQTLHDSVKRQMEKNQREYFLNEKMKVIQRELSDMNGGAEDDVAEIEKRLAEADLPEHVRKKAEAEFRKLKAMQPASSEAAVVRNYLEVILDTPWNKASKVSINLNKAQEILDADHYGLDDVKDRIVEYLAVQSRVKKLKGPILCLVGPPGVGKTSLGESVAKATGREFVRMALGGVRDEAEIRGHRRTYIGAMPGKIVQSLTKVGVKNPLFLLDEIDKMAQDYRGDPASALLEVLDPSQNSKFNDHYLDLDLDLSEVMFICTANSMNIPEALLDRMEVIRLPGYTEDEKVNIAERYLVPKAIKNNGLRPKELTIHEEAIRDIVQRYTREAGVRNLEREVSKIARKVVKEAVSKKSKNLQLDVTSANLPEYLGPHKFDFGMAEDEAQVGRVNGLAWTSVGGELLTIEVAAVKGKGKFITTGSLGDVMKESITTAMTVVRTRADELGIEASRFEETDVHVHLPEGATPKDGPSAGLALTTALVSAFTGIAIRPDIAMTGETSLGGRAMRIGGLKEKLLAAHRGGIKLVFIPQDNVRDLAEIPDNVKEGLEIKAVKSIDEILPLALTSMPKPLPKTPIVKPVEGSKAARH
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner.
What are the official names of this protein?
Lon protease, ATP-dependent protease La.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_NOCFA
Sequence: MTQTSERKSSAVEVEPGVFESVALIDNGSYGTRTVRFETGRLARQAAGSVVAYLDDETMLLSATTAGKTPKDQFDFFPLTVDVEERMYAAGRIPGSFFRREGRPSTDAILTCRLIDRPLRPSFVDGLRNEVQVVVTVLSLDPKDLYDVVAINAASASTQIAGLPFSGPVGGVRVALIPDQGANSAGGGQWVAFPTVEQLEGAVFDMVVAGRVVESGDVAIMMVEAEATEKVIELVEGGAQAPTEAVVAEGLEAAKPFIARLCRAQQDLAELAAKPTEEFPLFPPYGPDVYEAVEGAAEAELGEALSIAGKQEREEKIDEIKLAVLDRLAEQFAGREKELGAAFRSVTKKLVRQRILTDGFRIDGRGLADIRALSAEVAVVPRAHGSALFERGETQILGVTTLDMVKMAQQVDSLGPETSKRYMHHYNFPPFSTGETGRVGSPKRREIGHGALAERALIPVLPSQEDFPYAIRQVSEALGSNGSTSMGSVCASTLSLLNAGVPLKAPVAGIAMGLVSDTVTNDKGEQEVRYVALTDILGAEDAFGDMDFKVAGTREFVTALQLDTKLDGIPSQVLAGALSQAHDARTTILDVMAEAIATPDEMSPYAPRVTAIKIPVDKIGEVIGPKGKVINQITEDTGANISIEDDGTVFVGATDGPSAQAAIDAINAIANPQLPKVGERFLGTVVKTTAFGAFVSLLPGRDGLVHISKLGNGKRVAKVEDVVNVGDKLRVEIADIDNRGKISLVPVDENADEPAADAVDAGTE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP_WOLTR
Sequence: MTLIPIVIEQTSRGERAYDIYSRLVKERIIFVTGPVEDNMASVIVAQLLFLESENPDKDIYMYINSPGGVVTAGLSIYDTMQYIKPDVSTLCIGQAASMGSLLLAAGTEGKRYSLPHSRIMIHQPSGGYQGQATDIEIHANEILRVKRKLNQIYEKHTGNSLKKIEGMMERDKFMDPEEARRIGLIDRVIAERKDIKVENIKVEQKVG
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDGC_SHEB5
Sequence: MWFKNLTLYRFNKPFAVETEALETALADFTFSPCSSQDVSKFGFSNALGKKGSSLVHSADNRHLICVTKEEKILPGQVIKEALEEKVALIEDEENRKMAKKEKDALKDEIITSLLPRAFSRRSQTHALILPELEMILVDSSSATKAEELLALLRKALGSLPVIPLSFKAPVESNLTEWLKLGSAPLPFEMQDEAELKSEADEGGIVRFKQQDLKEDEVLAHLATGKQVHKLALHFGQSIALLLQSDASVKRLKFSEEFRAGNDEVGTDDPMARLDADFALMGSELVALMHALVAALGGLEEAQV
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: PVDR_PLAVS
Sequence: MKGKNRSLFVLLVLLLLHKVNNVLLERTIETLLECKNEYVKGENGYKLAKGHHCVEEDNLERWLQGTNERRSEENIKYKYGVTELKIKYAQMNGKRSSRILKESIYGAHNFGGNSYMEGKDGGDKTGEEKDGEHKTDSKTDNGKGANNLVMLDYETSSNGQPAGTLDNVLEFVTGHEGNSRKNSSNGGNPYDIDHKKTISSAIINHAFLQNTVMKNCNYKRKRRERDWDCNTKKDVCIPDRRYQLCMKELTNLVNNTDTNFHRDITFRKLYLKRKLIYDAAVEGDLLLKLNNYRYNKDFCKDIRWSLGDFGDIIMGTDMEGIGYSKVVENNLRSIFGTDEKAQQRRKQWWNESKAQIWTAMMYSVKKRLKGNFIWICKLNVAVNIEPQIYRWIREWGRDYVSELPTEVQKLKEKCDGKINYTDKKVCKVPPCQNACKSYDQWITRKKNQWDVLSNKFISVKNAEKVQTAGIVTPYDILKQELDEFNEVAFENEINKRDGAYIELCVCSVEEAKKNTQEVVTNVDNAAKSQATNSNPISQPVDSSKAEKVPGDSTHGNVNSGQDSSTTGKAVTGDGQNGNQTPAESDVQRSDIAESVSAKNVDPQKSVSKRSDDTASVTGIAEAGKENLGASNSRPSESTVEANSPGDDTVNSASIPVVSGENPLVTPYNGLRHSKDNSDSDGPAESMANPDSNSKGETGKGQDNDMAKATKDSSNSSDGTSSATGDTTDAVDREINKGVPEDRDKTVGSKDGGGEDNSANKDAATVVGEDRIRENSAGGSTNDRSKNDTEKNGASTPDSKQSEDATALSKTESLESTESGDRTTNDTTNSLENKNGGKEKDLQKHDFKSNDTPNEEPNSDQTTDAEGHDRDSIKNDKAERRKHMNKDTFTKNTNSHHLNSNNNLSNGKLDIKEYKYRDVKATREDIILMSSVRKCNNNISLEYCNSVEDKISSNTCSREKSKNLCCSISDFCLNYFDVYSYEYLSCMKKEFEDPSYKCFTKGGFKDKTYFAAAGALLILLLLIASRKMIKNDSEEATFNEFEEYCDNIHRIPLMPNNIEHMQPSTPLDYS
What is the function of this protein?
Binds to the human erythrocytes Duffy blood group determinant.
What are the official names of this protein?
Duffy receptor, Erythrocyte-binding protein.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: L83L_ASFB7
Sequence: MIMDTSLKNNDGALEADNKNYQDYKAEPDKTSDVLDVTKYNSVVDCCHKNYSTFTSEWYINERKYNDVPEGPKKAVVHRCTIL
What is the function of this protein?
May subvert the host innate immune response by interacting with host IL1B and interfering with its function.
What are the official names of this protein?
Protein L83L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus L83L family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: PEX2_DANRE
Sequence: MAGAGGDKPFAKAGPSPLSRVLRISQLDAFELDGALEQLVWSQFTQCFQHFKPGILTPVEPELKALLQLLLWRFTIYSNSATVGQSLLNIRYKNALIPGQKYRPMSRPQKFWFALLTVGEKWFRERSHSLFLNHPAESNARKARKVLSILLGLTKAASLVNFLLFLQRGTFPTLTERLLGVQPVFSRPQGPRDINFQYLNRELLWHGFAEFLIFLLPLINVWKLKAGVSALFSPLSDLTGTQSSEETHLTECAICGEWPTMPHSIGCKHVFCYYCVKSNVIADIYFTCPKCGAETGQIEPVRLQVGTELLQS
What is the function of this protein?
E3 ubiquitin-protein ligase component of a retrotranslocation channel required for peroxisome organization by mediating export of the PEX5 receptor from peroxisomes to the cytosol, thereby promoting PEX5 recycling (By similarity).  The retrotranslocation channel is composed of PEX2, PEX10 and PEX12; each subunit contributing transmembrane segments that coassemble into an open channel that specifically allows the passage of PEX5 through the peroxisomal membrane.  PEX2 also regulates peroxisome organization by acting as a E3 ubiquitin-protein ligase (By similarity).
What are the official names of this protein?
Peroxisome biogenesis factor 2, Peroxin-2.
What is the protein family that this protein belongs to?
Belongs to the pex2/pex10/pex12 family.
Protein: QUEC_SHIBS
Sequence: MKRAVVVFSGGQDSTTCLVQALQQYDEVHCVTFDYGQRHRAEIDVARELALKLGARAHKVLDVTLLNELAVSSLTRDSIPVPDYEPEADGIPNTFVPGRNILFLTLAAIYAYQVKAEAVITGVCETDFSGYPDCRDEFVKALNHAVSLGMAKDIRFETPLMWIDKAETWALADYYGKLDLVRNETLTCYNGIKGDGCGHCAACNLRANGLNHYLADKPTVMAAMKQKTGLR
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: HV323_HUMAN
Sequence: MEFGLSWLFLVAILKGVQCEVQLVESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAK
What is the function of this protein?
V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170).
What are the official names of this protein?
Immunoglobulin heavy variable 3-23, Ig heavy chain V-III region LAY, Ig heavy chain V-III region POM, Ig heavy chain V-III region TEI, Ig heavy chain V-III region TIL, Ig heavy chain V-III region TUR, Ig heavy chain V-III region VH26, Ig heavy chain V-III region WAS, Ig heavy chain V-III region ZAP.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: TRPF_XANC8
Sequence: MNRSLYRTRIKFCGMTRAGDIRLAGELGVDAVGFIFAHGSPRRVAPAEARAMRQATAPMVDVVALFRNNSKEEVREVVRTVRPTLLQFHGEEDDAFCRSFNLPYLKAVPMGASGVNGEDANARTLQLAYPNTAGFLFDSHAPGEGGGTGKTFDWSRLPTGLHRPFLLAGGITADNVFDAIVATLPWGVDVSSGVELAPGIKDGHKMRKFVEEVRRADCHEMS
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: RL5_CORK4
Sequence: MSENYTPRLKTRYRSEIRETLNKEFEYANVMQIPGVTKVVVNMGVGDAARDSKLINGALNDLTLITGQKPQIRRAKKAIANFKLREGMPIGARVTLRGDRMWEFLDRLLTVALPRIRDFRGLSDKQFDGHGNYTFGLSEQSMFYELDVDKIDRPRGMNITVVTSATNNEEGRALLRELGFPFKK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: HIS5_RENSM
Sequence: MMATVTVLDYGSGNVRSAVRALERAGAEVTLSAKADDVLNADGLVVPGVGAFATVMKELKSVDALRMIGRRVAGGRPVLAICVGLQILFEAGVEHGNSEPGMGEWPGTVELLPADVVPHMGWNTVQAPADSMLFDGVRDERFYFVHSYGVQHWDFDVTQPKMKPPAVTWSEHGAKFIAAVENGPLCATQFHPEKSDDAGARLLKNWVDSLPATGRNQVA
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.