PharMolix/UniProtQA huggingface dataset:
Protein: YQGE_SALNS
Sequence: MNLQHHFLIAMPALQDPIFRRSVVYICEHNQDGAMGIIINKPLENLQIEGILEKLKITPEPRDSAIRLDKAVMLGGPLAEDRGFILHTPPSRFASSIRISDNTVITTSRDVLETLGTQQQPSDVLVALGYASWDKGQLEQELLDNAWLTAPADLNILFKTPIAERWREAAKLIGIDILTMPGVAGHA
What are the official names of this protein?
UPF0301 protein YqgE.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: ATPA_METS4
Sequence: MDIRAAEISAILKEQIKNFGQEAEVTEVGQVLSVGDGIARVYGLDNVQAGEMVEFESGVRGMALNLEQDNVGVVIFGVDRDIKEGQTVKRTGAIVDVPVGKGLLGRVVDALGNPIDGKGPIVSTERRRVDVKAPGIIPRKSVHEPMATGLKSVDALIPIGRGQRELIIGDRQTGKTAIALDTILNQKPAHEGTDEKAKLYCVYVAVGQKRSTVAQFVKVLEDNGALDYSIVIAATASDPAPMQFLAPFSGCAMGEFFRDNGMHAVIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMGDAAGAGSLTALPVIETQANDVSAYIPTNVISITDGQIFLETDLFYQGVRPAVNVGLSVSRVGSAAQTKAMKKVAGKIKGELAQYREMAAFAQFGSDLDAATQRLLNRGSRLTELLKQPQFSPLKMEEQVAVIYAGVNGYLDAIPVNRVRAFEDGLLSTLRGRHADLLETIRTSKDLGDDAAAKLKGVVESFAKSFS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL14_CLOBB
Sequence: MIQPQTLLKVADNSGAKEIMCIRVLGGSKRKFGNISDVIVASVKSATPGGVVKKGEVVKAVIVRSAKGLRRADGSYIKFDENAAVIIKDDKQPRGTRIFGPVARELRDKEFNKILSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: HIS4_LEGPL
Sequence: MLVIPAIDLQSGRCVRLKQGRFDQVTQFSVFPIERALHFAKLGAKRLHVVDLDGARSGKMQQLELICSMQKTGIAIQAGGGIRSIEQALECSNAGISQLVIGSLAITNPDLTIQIIEKIKPENIVLALDVRVDTKVPLLAINGWQNNSTSSLWEVVSYYENHGIKHILCTDIACDGMMNGPNFDLYQQAVEYFPQIAWQASGGIRHMQDITTLGSLGISAVILGLMLYQDNVNFEELLC
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_SHIFL
Sequence: MGLSTLEQKLTEMITAPVEALGFELVGIEFIRGRTSTLRIYIDSEDGINVDDCADVSHQVSAVLDVEDPITVAYNLEVSSPGLDRPLFTAEHYARFVGEEVTLVLRMAVQNRRKWQGVIKAVDGEMITVTVEGKDEVFALSNIQKANLVPHF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COFH_GLOVI
Sequence: MRDWKRLHATLDAAREGREMTVPEAAFLLGQTDPAARELVRSAADRLRAELVGERVSYVINRNINFSNICVQHCSFCAFRRDAQEAGAYSLDFAHILQKTAEAVASGATEICMQGGLNPAVRGAGGRVLDYYLQLVDAIKAPFPRIHLHAFSPQESFFIAREDRLPIETVLAELRAAGVDSMPGTAAEVLHEPVRRRLCPEKLSTLAWVRTVEAAHRTGLPMTSTMLSGHIETAMHRAIHLGVLRTIQKRTGGFTEFVLLPYVGLAAPRALRARVGRDQPELADALLTQAVARLFFGRSLVNHQPSWVKLGLEGAGEALRWGCNDIGGTLMEEHITSMAGARGGTCQTPEALRAAVFQAERTAYQRDTLYQEVAAESIQPAASLKSAAR
What is the function of this protein?
Catalyzes the radical-mediated synthesis of 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
What are the official names of this protein?
5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase, FO synthase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. CofH family.
Protein: PRP5_CHAGB
Sequence: MTITEAVAVMEEAIETVVGHATEAQTERDRQIAEDNGAEMVTGTTAPAKSTPTQAQTEAEKKAERLRKLQAMKEKHAQKEAKEAAVTAGSTRMLLAEMDQKASGTPGPNSPVAGAMSPAPTSPAPPMPYAGKFDPKAIAKSSKAARPQSPTRLGDVKLAAPAPKPLGLKKEANLKGAGLLPANRAKSSTKRKIDMDDEEVIKRKLVKLPDFVPENADSTPDAEGEGEEEADDLDLLMAQNEEEMAEAHRVLQERRDERIQKEGMAMDVDTETPNGETKDEAENEANVESKDEAVLPAPSMDVDEDVDPLDAFMADLEQTGSAGGIGSVPARQKQKAGKGFEPEAYFSDDDYGYEEDKADPSSILAMASKKKKKDIPTIDYSKIELNQIRKNFWVEPQELSQMTEDDIADLRLELDGIKVSGKNVPKPVQKWSQCGLTRPILDVVEGLGYEKPTSIQMQALPVIMSGRDVIGVAKTGSGKTMAFVLPMLRHIKDQDPVTGDDGAIALIMTPTRELCTQIYSDLLPFAKALKLRAIAAYGGNAIKDQIAELKRGAEIIVATPGRMIDLLAANSGRVTNLKRATYLVLDEADRMFDMGFEPQVMKIFNNVRPDRQTILFSATMPRIIDALTKKVLREPVEIQVGGRSVVAPEITQIVEILDEGKKFVRLLELLGELYADDDDVRALIFVERQEKADDLLREVLRRGYGCMSIHGGKDQEDRNSTISDFKKGVCPIMIATSVAARGLDVKQLKLVVNYDAPNHLEDYVHRAGRTGRAGNTGTAVTFITEEQENCAPGIAKALEQSGQPVPEQLNEMRKAWKEKVKTGKAKDASGFGGKGLERLDKEREAARVRERKTHKAEGEEDDFKEEETAEDAAKKDKAKSAILAAASAIVSRESAKADASEAKPLPAAAEGAVKGGVTVNAGKGGALDKAASAISEINARLARAGQLRPGQPIDNKGPDAGAFHATLEINDFPQKARWAVTNRTNVAKILEATSTSITTKGNYYPPGKEPPSGSDPKLYILIEGDTELAVGKALSELTRLLREGTIAAADAESRAPASGRYTIA
What is the function of this protein?
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing.  Catalyzes an ATP-dependent conformational change of U2 snRNP.  Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
What are the official names of this protein?
Pre-mRNA-processing ATP-dependent RNA helicase PRP5.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: COW_CONLV
Sequence: ILLLVAAVLLSTQVMVQGDGDQPAYRNAVPRDDNTGGASRKFLNVPRESECPWRPWCG
What is the function of this protein?
Its target is unknown, but this toxin may modulate voltage-activated calcium channels (Cav) or calcium-dependent potassium channels (KCa).
What are the official names of this protein?
Contryphan-Lnv.
What is the protein family that this protein belongs to?
Belongs to the O2 superfamily. Contryphan family.
What are the subcellular locations of this protein?
Secreted.
Protein: IOLA3_BACCZ
Sequence: MTVQTAQIVKNYIGGEWVESISTKMEAVYNPATGEVIAQVPLSTKVDVEQAVLAANEAFKSWSKTAVPKRARILFKYQQLLVDNWEDLAKLITIENGKSYNEAYGEVLRGIECVEFAAGAPTLMMGKQLPDIATGIESGMYRYPIGVIGGITPFNFPMMVPCWMFPLAIACGNTFVLKPSERTPLLAAKLVELAEEAGLPKGVLNIVNGAHDVVNGLLEHKLVKAISFVGSQPVAEYVYKKGTENLKRVQALAGAKNHSIVLSDANLELATKQIISAAFGSAGERCMAASVVTVQEEIADQLVGRLVEEANKIVIGNGLDEDVFLGPVIRDNHKERTIGYIDSGVEQGATLVRDGREDTAVKGAGYFVGPTIFDHVTQEMKIWQDEIFAPVLSIVRVKSLDEAIEIANESRFANGACIYTDSGASVRQFRETIESGMLGVNVGVPAPMAFFPFSGWKDSFYGDLHANGTDGVEFYTRKKMLTSRWEK
What is the function of this protein?
Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively.
What are the official names of this protein?
Malonate-semialdehyde dehydrogenase 3, MSA dehydrogenase 3, Methylmalonate-semialdehyde dehydrogenase 3, MMSA dehydrogenase 3, MSDH 3.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. IolA subfamily.
Protein: NUOI_SHISS
Sequence: MTLKELLVGFGTQVRSIWMIGLHAFAKRETRMYPEEPIYLPPRYRGRIVLTRDPDGEERCVACNLCAVACPVGCISLQKAETKDGRWYPEFFRINFSRCIFCGLCEEACPTTAIQLTPDFEMGEYKRQDLVYEKEDLLISGPGKYPEYNFYRMAGMAIDGKDKGEAENEAKPIDVKSLLP
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HIS1_SYNP6
Sequence: MLTIALPKGALLKDSIRLLQSAGLDFSAFLEPGNRQLQILDRQERAKALLVRNSDVPVYVEYGQAQLGVVGYDVLREKTARVAQLIDLRFGGCRMSIAVKASSPYRSVLDLPAHCRIASKFVHCARDYFHNLDLPVEIVPLSGSVELGPITGMSEAIVDLVATGQTLRENGLVEIETLFDSTARLIANPLAYRINADGISELIEELRQSVTQAIAATC
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COQ8B_MOUSE
Sequence: MWLELGAMLRRTCGPLGRAVRLPCGGALGPRPHWWGPCRSCLAQSVHQDQPGRGLSEDDIRRAREARLRKAPRPQLSDRSRERKVPASRISRLASFGGLAVGLGLGALAEVTKKSLPGGSLQHEGVSGLGSSPFLSEANAERIVQTLCTVRGAALKIGQMLSIQDNSFISPQLQRIFERVRQSADFMPRWQMMRVLEEELGKDWQDKVASLEEVPFAAASIGQVHQGLLKDGTEVAVKIQYPGVAQSIQSDVENLLALLKMSVGLPEGLFAEQSLQTLQQELAWECDYRREAACAQTFRKLLADDPFFRVPAVVQELCTTRVLGMELAGGIPLDQCQGLSQDIRNQICFQLLRLCLRELFEFRFMQTDPNWANFLYDASSHQVTLLDFGASRAFGTEFTDHYIEVVKAAADGDRDRVLQKSQDLKFLTGFETKAFSDAHVEAVMILGEPFAASGPYDFGAGETARRIQGLIPVLLRHRLRPPPEETYALHRKLAGAFLACARLHAHIACRDLFQDTYHRYWASRQTLPLPAAS
What is the function of this protein?
Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.  Its substrate specificity is unclear: does not show any protein kinase activity.  Probably acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway.  Required for podocyte migration.
What are the official names of this protein?
Atypical kinase COQ8B, mitochondrial, AarF domain-containing protein kinase 4, Coenzyme Q protein 8B.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. ADCK protein kinase family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein. Cytoplasm, cytosol. Cell membrane.
Protein: CA074_HUMAN
Sequence: MLLLDLMSSPSPQLLVAAAQQTLGMGKRRSPPQAICLHLAGEVLAVARGLKPAVLYDCNCAGASELQSYLEELKGLGFLTFGLHILEIGENSLIVSPEHVCQHLEQVLLGTIAFVDVSSCQRHPSVCSLDQLQDLKALVAEIITHLQGLQRDLSLAVSYSRLHSSDWNLCTVFGILLGYPVPYTFHLNQGDDNCLALTPLRVFTARISWLLGQPPILLYSFSVPESLFPGLRDILNTWEKDLRTRFRTQNDFADLSISSEIVTLPAVAL
What are the official names of this protein?
UPF0739 protein C1orf74.
What is the protein family that this protein belongs to?
Belongs to the UPF0739 family.
Protein: NOVP1_PITAZ
Sequence: FLFFAFPHPL
What are the official names of this protein?
Novel peptide 1, PRP-HA1.
What are the subcellular locations of this protein?
Secreted.
Protein: RL3_SALEP
Sequence: MIGLVGKKVGMTRIFTEDGVSIPVTVIEVEANRVTQVKDLANDGYRAVQVTTGAKKANRVTKPEAGHFAKAGVEAGRGLWEFRLAEGEEYTVGQSISVELFADVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKKMAGQMGNERVTVQSLDVVRVDAERNLLLVKGGVPGATGCDLIVKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: C1331_XYLFT
Sequence: MKLTDLSNPAFLENPYPLYETLRAQAPFVSIGPNALMTGRYSLVDSLLHNRNMGKKYIESIRLRYGDTAADMPLFQAFSRMFITINPPAHTHLRGLVMQAFTGRESESMRPLAIDTAHQLIDNFEQKPSVDLVAEFAFPFPMQIICKMMDVDIGDAVTLGMAVSKIAKVLDPSPMSADELVHASTAYEELAQYFTKLIELRRTHPGTDLISMFLRAEEDGEKLTHDEIVSNVIMLLIAGYETTSNMIGNALIALHRHPEQLALLKSDLSLMPQAVSECLRYDGSVQFTMRAAMDDIEVEGELVPRGTVVFLMLGAANRDPAQFTHPDQLDITRKQGRLQSFGAGIHHCLGYRLALIELECALTTLFERLPHLRLAHLDALNWNQRSNLRGVNTLIVDLHAKN
What are the official names of this protein?
Putative cytochrome P450 133B1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: DADA_VIBCM
Sequence: MMEVLVLGSGVVGLTSAWYLAQAGHDVTVVDRQPRGAEETSFANAGQISYGYSSPWAAPGIPQKALKWMLEKHAPLKIQPSLDPALLSWMGKMLLNCQLSRYQVNKSRMLAIANYSRECLKALNQTYSLDYQGRQRGTLQVFRDEKQLTAIEKDMQLLAQSGVRFELLNVAQCLTHEPGLAPVQEKLVGGLWLPDDETGDCYLFCQQLTELAKQQGVRFHFDCHIQQLVCEGKKIIGVQTDLGLLKADAYVVALGSYSTSLLKPLGIEIPVYPVKGYSLTLPIIDEKFAPQSTVMDETYKVALTRFSDRIRVAGTAELAGFDPAIPEARKATIEMVARDLFPHGGDFAKGQFWTGFRPMTPDGTPIIGATPYTNLYTNTGHGTLGWTMACGSASILADVLTHGESPLSRLGLDLFRYPKAS
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: YO34_BPHC1
Sequence: MQKRNPSVQLALNGTPIYLNNILMSVSVKREEKDMSGQKSSTKKSDKGVKAKELSVTGFIPYNRKEWLTQLFNLAEAETGKGEQTKYRVSCTVAEAVNMREVQFSGEVSATEQNGQLGWSISFRLREVNSVAEKKDQRKKKPKVKTQGENAPVAKSAGENSGKLEEQKDERKGIAKDIDDFFGGIDG
What are the official names of this protein?
Uncharacterized 20.8 kDa protein in lys 3'region, ORF34.
Protein: RS17_PARMW
Sequence: MAVKERVGTVVSDKMEKTVVVAVESRFPHPIYQKTVSRTTRYKAHDEDNSCRVGDRVRITETRPMSRHKRWAIAEVLSHSPKADKSAGSTAPAPEAAAKEVSE
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: Y2716_DICDI
Sequence: MENNNSLTIIKKADPKTKSNGEAFQIAFDSMDKIKTMLTQQNDKEKLVLKKLMIEMSINNSLLNELLTSFSTRVNIIDVEIIVLESQISTIERLTLENKKEIQSNDQEKIKEISSMIDKLIDPLLKNIDGLTNKFTEKNVNDEELKKKIDVFFENSKKLFQGIDKAEKSQFLTKFSSLFGVISGFLGIGSVTAIGATEAVGVTSLIAVGATSLSVVAPICAPVLLTFGCLVGAFISFYKQSVARDKKLKTLKSLLSYYMENIELISQVTDETTKLIYHELKEKVLEFKKLEANLKIDFDLSPIKDQFKSITSKQNLIKDKVEEIANYQLDLIQECQKLKKKSLKNKTINKK
What are the official names of this protein?
Transmembrane protein DDB_G0272716.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RDRP_PAV
Sequence: MEEHIPLPSQYESPKALPPRVPSSRWLRSLRPRLANSCLALKIRAHESLVKIRLCKPYDAQSRSKIIEKVIERRETRKTLAHQLKDLKLVPVARDHTHGRAAKFRTSANIWMNEAMRAAGYEPYNVSMSNHDIERGNRYFYFAKDLTIPYRNDPVSDNTGFVFCDVDYYADMEKWMQHFKPMLLYTLVPESLSYHCDDHSFHVNDDRVFFDVRGGASYSHQLWDYTGDTICVRGKNKELLVFTIEQKCIQGDPHRRIIFLEPAARVAWPFYKPMKVEVGLKRKCMTAGQVNVLYEPIDDKISLSASGSRHTVETTGRTLAAITARMKNKTSPPMVADVERILRDAGDKEACVNAPILFELIPEAKFRVNVVKTTATPTHFQPLGPLRTEDGETCGHAVTTTLATAPALLPMRGVNSDVATVNGRVKKPANTVIPFKEYKEYASEFVEFLVPEPGVGHPWDTAAVREVQDNRQQKARINMVAATVSTHSSNRLKAFIKAEAYAATNDPRNITTMAPELTLMMSCFTYAFKEKILYEQPWYGPGKTPKQVGRRLQSIAKHGTLESDYSRFDGSISEWLQKNVVKAAYMRFFKEHQRTEFQSWFSKVFMQMGTTTAGVRYEAGWGTRSGSPITTDGNTMLNAFVVYCCYRKLCHTPAEAWRKLSQGALLTGDDAVLAHENGLEPALLDVVKNLGLKVEAKVNGPDDPVSFCGRIYPRLSDCITSFQDPLRTIPKLHLTTNKGVSPEQAAANRAHGYLATDKATPIIGTWARRVIELTGDLKVKGATREEQYKLSNAHQQLDPSLIETAMANILGIDVGELKALDKAVSEAKALDQMPVVLGNCYKHKIEAVVGGEVVGPGPRVETVEPNHEQSSGTPEVVPEMAGHSERRDKSSNPRPGGKAEGLSSKAGKPRVPTRPAADRKAAAGSGNRRGPTNGRRPIRDRAPRGGGRPNPGTTPPVSNSETTTTTAVVHASA
What is the function of this protein?
RNA-dependent RNA polymerase which replicates the viral genome composed of 2 RNA segments, RNA1 and RNA2.
What are the official names of this protein?
RNA-directed RNA polymerase, RdRp, RNA replicase, Protein A.
What is the protein family that this protein belongs to?
Belongs to the nodaviridae RNA polymerase family.
Protein: ISPG_PHOPR
Sequence: MHSESPIIRRQSTRIYVGDVPIGDGAPIAVQSMTNTLTTDVAATVAQIRALEKVGADIVRVSVPTMDAAEAFKLIKQQVNIPLVADIHFDYRIALKVAEYGVDCLRINPGNIGNEERIRSVVECARDYNIPIRIGINGGSLEKEIQLKYGEPTPDALVESAMRHVDILDRLNFDQFKVSVKASDVFLAVESYRRLAKQIKQPLHLGITEAGGARAGSVKSAVGLGMLLAEGIGDTLRISLAADPVEEIKVGFDILKSLRIRSRGINFIACPTCSRQEFDVIGTVNELEQRLEDITTPMDVSIIGCVVNGPGEAEVSHLGVAGSSRKSAFYEDGIRQKERFDNDNVIDQLETKIRAKAAMLDVNNRINVQEVEK
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: PDXS_PASMU
Sequence: MNTILGSDTVKRGMAQMQKGGVIMDVVNAEQARIAEAAGAVAVMALERVPSDIRAAGGVARMANPKIVKEVMNAVSIPVMAKARIGHITEARVLEAMGVDYIDESEVLTPADDEFHLLKCEFTVPFVCGCRDLGEALRRIGEGASMLRTKGEPGTGNIVEAVRHIRKVNAQIRKVVAMNHDELMTEAKNLSAPFELLLQIKALGKLPVVNFAAGGVATPADAALMMELGADGVFVGSGIFKSEHPEKFAKAIVQATTHYQDYDLIARLSEELGEPMKGIEISRLQQHERMQERGW
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: ADE_RHIE6
Sequence: MTSHLKKVELHCHLEGAAPPALTEAQARKYGIDMSEQLRDGAYVWHDFASFLECYDKVSEVYKTEEDYALLTETYLDELAAINTIYSELIVSPDHGKRIGLGADAYISGVCEGIRRAKEKSGIEARLIVTGERHFGPDSVIGAAEYAAKAGNPLITGFNLAGEERMGRVADYSRAFDIARDAGLGLTIHAGEVCGAFSVADALDAVRPARIGHGVRAIEDLDLVKRLADLGTVLEVCPGSNIALRVYPDFASHPLRRLKEAGVPVTISSDDPPFFHTSLEREYALAAEAFGFDNAEIDAMTRTAIEAAFVDAQTRKALLARL
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenine to hypoxanthine.  Plays an important role in the purine salvage pathway and in nitrogen catabolism.
What are the official names of this protein?
Adenine deaminase, ADE, Adenine aminohydrolase, AAH.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
Protein: MURB_BACSU
Sequence: MEKVIQELKEREVGKVLANEPLANHTTMKIGGPADVLVIPSSVDAVKDIMDVIKKYDVKWTVIGRGSNLLVLDEGIRGVVIKLGAGLDHLELEGEQVTVGGGYSVVRLATSLSKKGLSGLEFAAGIPGSVGGAVYMNAGAHGSDMSEILVKAHILFEDGTIEWLTNEQMDFSYRTSVLQKKRPGVCLEAVLQLEQKDKESIVQQMQSNKDYRKNTQPYSSPCAGSIFRNPLPNHAGNLVEKAGLKGYQIGGAKISEMHGNFIVNAGGASAKDVLDLIDHVKKTIREKYEIDMHTEVEIIGGNR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBL5_DROME
Sequence: MIEITCNDRLGKKVRVKCNPDDTIGDLKKLIAAQTGTKHEKIVLKKWYTIFKDPIRLSDYEIHDGMNLELYYQ
What are the official names of this protein?
Ubiquitin-like protein 5.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LACC_STRPB
Sequence: MILTVTLNPAIDVSYPLDELKCDTVNRVVDVTKTPGGKGLNVSRVLNDFGETVKATGCVGGESGDFIINHLPDSILSRFYKISGDTRTCIAILHEGNQTEILEKGPLLSVDEIDGFTHQFKYLLNDVDVVTMSGSLPAGMPDDYYQKLIKIANLNGKKTVLDCSGNALEAVLKGDSKPTVIKPNLEELSQLLGKEMTKDFEALKEVLQDELFEGIEWIIVSLGADGVFAKHKDTFYNVDIPKIKIVSAVGSGDSTVAGIASGLANDEDDRALLTKANVLGMLNAQEKTTGHVNMANYDKLYQSIKVKEV
What are the official names of this protein?
Tagatose-6-phosphate kinase, Phosphotagatokinase.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
Protein: Y589_BACAA
Sequence: MGFPKEGEKVQIHSYKHNGSIHRMWKETTILKGTQSLVIGANDRTVVTESDGRTWITREPAICYFHENYWFNVIGMLREEGVYYYCNLSSPFAYDSEALKYIDYDLDIKVYPDMTYTLLDEDEYEKHSQIMQYPPVIDTILKRNVAQLTQWIHQRKGPFAPDFVDMWYERYLMYRN
What are the official names of this protein?
UPF0374 protein BAA_0589.
What is the protein family that this protein belongs to?
Belongs to the UPF0374 family.
Protein: RNC_EHRCJ
Sequence: MIETISKTIKYHFKNPQLLHEALTHPSIISKDSLKFNYERLEFLGDAVLNIVISEMLFNIFPKDTEGNLAKKKTALVCGNQLVKVAQSINLGQFIIMSDGERTCGGANNHNNLENALEALIGAIYLDGGLTAAQNFIHSFWKHTAIHMDIPPQDAKTILQEFIQGKRLPAPTYHIIDKSGPDHNPIFTVELRIPLYKTIQATGNNKKLAEQKAASLMLNQIKDQIK
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OCLN_HUMAN
Sequence: MSSRPLESPPPYRPDEFKPNHYAPSNDIYGGEMHVRPMLSQPAYSFYPEDEILHFYKWTSPPGVIRILSMLIIVMCIAIFACVASTLAWDRGYGTSLLGGSVGYPYGGSGFGSYGSGYGYGYGYGYGYGGYTDPRAAKGFMLAMAAFCFIAALVIFVTSVIRSEMSRTRRYYLSVIIVSAILGIMVFIATIVYIMGVNPTAQSSGSLYGSQIYALCNQFYTPAATGLYVDQYLYHYCVVDPQEAIAIVLGFMIIVAFALIIFFAVKTRRKMDRYDKSNILWDKEHIYDEQPPNVEEWVKNVSAGTQDVPSPPSDYVERVDSPMAYSSNGKVNDKRFYPESSYKSTPVPEVVQELPLTSPVDDFRQPRYSSGGNFETPSKRAPAKGRAGRSKRTEQDHYETDYTTGGESCDELEEDWIREYPPITSDQQRQLYKRNFDTGLQEYKSLQSELDEINKELSRLDKELDDYREESEEYMAAADEYNRLKQVKGSADYKSKKNHCKQLKSKLSHIKKMVGDYDRQKT
What is the function of this protein?
(Microbial infection) Acts as a coreceptor for hepatitis C virus (HCV) in hepatocytes.
What are the official names of this protein?
Occludin.
What is the protein family that this protein belongs to?
Belongs to the ELL/occludin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, tight junction.
Protein: TIG_THESQ
Sequence: MEVKELERDKNRVVLEYVFGAEEIAQAEDKAVRYLNQRVEIPGFRKGRIPKNVLKMKLGEEFQEYTLDFLMDLIPDTLKDRKLILSPIVTERELKDVTARVVVEVHEEPEVRIGDISKIEVEKVDEEKVLEKYVERRIEDLRESHALLEPKEGPAEAGDLVRVNMEVYNEEEKKLTSREYEYVISEDEDRPFVKDLVGKKKGDVVEIEREYEGKKYTYKLEVEEVYKRTLPEIGDELAKSVNNEFETLEQLKESLKKEGKEIYDVEMKESMREQLLEKLPEIVEIEISDRTLEILVNEAINRLKREGRYEQIVSSYESEEKFREELKERILDDIKRDRVIEVLAQEKGISVNDEELEKEAEELAPFWGISPDRAKSLVKARQDLREELRWAILKRKVLDLLLQEVKVKVVEPKGEGDDSEGKEDN
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: EX7L_NITSB
Sequence: MNVYTVSQLNEQIKNLLESHFVEVYVEGEVSRPTYHTSGHLYFSLKDEKSVIRCVMFRSALAKVPFRVEDGQKLIVAGKIGVYKPRGEYQLYATELHPSGVGSLQLAFEQLKAKLEKKGYFASELKKPLPDFIQTIALVTSQTGAALQDMLRIIQNRWPLVKVYVVDTLVQGSDAAPMIARSIAYADGLGVDVIVVGRGGGSLEDLWPFNEEIVADAIFEAKTPIVSAVGHEIDFLISDFVADLRAPTPSAAMEMILPDRQEMLMHLDLLMQRLTKRMQTILQLKTQELGHLQNSLFQLSPQKRLEFYEKEITIMNERMNETITAILKNSSHEIPHLKALFDQKIEWIWKQKKQDLTSLQQKLTMTMEAKKIPKNSAQMVKNGKPVSLEDIDVGDEVELQDVHYKALAKILSKDAL
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_SALHS
Sequence: MTHWPSPAKLNLFLYITGQRADGYHTLQTLFQFLDYGDTLHIEPRRDGEIHLLTPVNGVENEDNLIVRAARLLMKIASESGRLPAGSGADISIEKRLPMGGGLGGGSSNAATVLVALNHLWQCGLSIDELATLGLTLGADVPVFVRGHAAFAEGVGEILTPVNPPEKWYLVAHPGVSIPTPVIFKDPQLPRNTPKRSIDTLLKCEFSNDCEVIARKRFREVDAALSWLLEYAPSRLTGTGACVFAEFDTESCARQVLEQAPEWLNAFVAKGVNLSPLHRELL
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.