PharMolix/UniProtQA huggingface dataset:
Protein: PA_I30A0
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDPRIETNKFAAICTHMEVSFMYSDFHFINERGESIIVESGDPNALLKHRFEIIEGRDRAMAWTVVNSICNTTGVGKPKFLPDLYDYKEDRFIEIGVTRREVHIYYLEKANKIKSEETHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSERGEETIEERFEITGTMRRLADQSLPPNFSSLENFRAYVDGFEPNGYIEGKLSQMSKEVNARIEPFLKTTPRPLRLPGGPPCFQRSKFLLMDALKLSIEDPSHEGEGIPLYDAIKCMKTFFGWKEPIIVKPHEKGINSNYLLAWKQVLAEIQDIESEKKVPRTKNIKKTSQLKWALGENMAPEKVDFDDCKDVSDLKQYDSDEPEFRSLASWIQSEFNKACELTDSSWIELDEIGEDVAPIEHIASMRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKWEKYCVLEIGDMLLRTSIGQVSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAESSVKEKDMTKEFFENKSETWPIGESPKGVEEGSIGKVCRTLLAKSVFNSLYASPQLEGFSAESRKLLLIVQALRDNLEPGTFDLGGLYESIEECLINDPWVLLNASWFNSFLTHALR
What is the function of this protein?
Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits.  The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching.  It consists in the hijacking and cleavage of host capped pre-mRNAs.  These short capped RNAs are then used as primers for viral mRNAs.  The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
What are the official names of this protein?
Polymerase acidic protein, RNA-directed RNA polymerase subunit P2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=PB1 and PA are transported in the host nucleus as a complex.
Protein: TSP_BPT4
Sequence: MTLLSPGIELKETTVQSTVVNNSTGTAALAGKFQWGPAFQIKQVTNEVDLVNTFGQPTAETADYFMSAMNFLQYGNDLRVVRAVDRDTAKNSSPIAGNIDYTISTPGSNYAVGDKITVKYVSDDIETEGKITEVDADGKIKKINIPTGKNYAKAKEVGEYPTLGSNWTAEISSSSSGLAAVITLGKIITDSGILLAEIENAEAAMTAVDFQANLKKYGIPGVVALYPGELGDKIEIEIVSKADYAKGASALLPIYPGGGTRASTAKAVFGYGPQTDSQYAIIVRRNDAIVQSVVLSTKRGEKDIYDSNIYIDDFFAKGGSEYIFATAQNWPEGFSGILTLSGGLSSNAEVTAGDLMEAWDFFADRESVDVQLFIAGSCAGESLETASTVQKHVVSIGDARQDCLVLCSPPRETVVGIPVTRAVDNLVNWRTAAGSYTDNNFNISSTYAAIDGNHKYQYDKYNDVNRWVPLAADIAGLCARTDNVSQTWMSPAGYNRGQILNVIKLAIETRQAQRDRLYQEAINPVTGTGGDGYVLYGDKTATSVPSPFDRINVRRLFNMLKTNIGRSSKYRLFELNNAFTRSSFRTETAQYLQGNKALGGIYEYRVVCDTTNNTPSVIDRNEFVATFYIQPARSINYITLNFVATATGADFDELTGLAG
What is the function of this protein?
Structural component of the bacteriophage tail which consists of a contractile sheath, a tube and a baseplate.  The central cylindrical segment of the tail consists of a rigid tube, composed of multiple copies of gp19, surrounded by the outer contractile sheath assembled from gp18 subunits.  A total of 138 copies of gp18 arranged into 23 hexameric rings constitutes the sheath.  During infection, contraction of the sheath drives the central tube through the host outer membrane, creating a channel for DNA ejection from the capsid into the host cell.
What are the official names of this protein?
Tail sheath protein, TSP, Gene product 18, gp18.
What is the protein family that this protein belongs to?
Belongs to the myoviridae tail sheath protein family.
What are the subcellular locations of this protein?
Virion.
Protein: RL28_METEP
Sequence: MSRRCELTGKAVQVGHLVSHSNRKTKCRFLPNLCNVTLQSDTLNRRVRLRVTAHALRSVEHRGGLDAFLVKAREIELSQTARLLKREIEKKIAEPATPAAA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: PX12A_XENLA
Sequence: MAERGAHITTTSASDDRPSIFEVVAQESLMAAARPALHHIVKVLAESNPSRYGTLWRWFDELYTLLDWLLQQHYLSWASASFSENFYGLKRITLGKEVGQRNLPRKEYWKSLLLLVLIPYLRVKLEKIVNRLREEQDYSIQNPTSFHKRCYKAILASYPFVKLGWEAWFLFYQLRYILWNGKNHSPLLRLAGVQLTRLTMEDLHAMEKQEEMTNTLSNAVSLSQRIRSILKKALGAVALSVSSSLSLGVFFLQFLDWWYSAENQETLKSLNNLPVPPPPIHFELETYSPLLPKLKTVCPLCRKVRVNDTALGTSGYVFCYRCAYYYVKTHQRCPVSGYPTELQHLIKLYTPDG
What is the function of this protein?
Component of a retrotranslocation channel required for peroxisome organization by mediating export of the PEX5 receptor from peroxisomes to the cytosol, thereby promoting PEX5 recycling (PubMed:35931083).  The retrotranslocation channel is composed of PEX2, PEX10 and PEX12; each subunit contributing transmembrane segments that coassemble into an open channel that specifically allows the passage of PEX5 through the peroxisomal membrane (By similarity).  PEX12 also regulates PEX5 recycling by activating the E3 ubiquitin-protein ligase activity of PEX10 (By similarity).  When PEX5 recycling is compromised, PEX12 stimulates PEX10-mediated polyubiquitination of PEX5, leading to its subsequent degradation (By similarity).
What are the official names of this protein?
Peroxisome assembly protein 12-A, Peroxin-12-A.
What is the protein family that this protein belongs to?
Belongs to the pex2/pex10/pex12 family.
Protein: SCD5_BOVIN
Sequence: MPGPAVDAEKVPFRSAKEEIRAGVGVEGSEGGGGGGGRERPGARGHRQDIVWRNVFLMSLLHLAAVYSLVLIPKAQPLTLLWAYFCFLLTALGVTAGAHRLWSHRSYKAKLPLRIFLAAANSMAFQNDIFEWSRDHRVHHKYSETDADPHNARRGFFFSHIGWLFVRKHRDVIEKGRKLDVTDLLADPVVRFQRKYYKITVVLMCFVVPTLVPWYIWGESLWNSYFLASILRYTISLNVTWLVNSVAHMYGNRPYDKHISPRQNPLVTLGAIGEGFHNYHHTFPFDYSASEFGLNFNPTTWFIDFMCWLGLATDRKRATKQMIEARKARTGDGSA
What is the function of this protein?
Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.  Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA.  Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids.  Involved in neuronal cell proliferation and differentiation through down-regulation of EGFR/AKT/MAPK and Wnt signaling pathways.
What are the official names of this protein?
Stearoyl-CoA desaturase 5, Acyl-CoA-desaturase 4, Stearoyl-CoA 9-desaturase.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RL25_PSEMY
Sequence: MTDFALNAEVRSDLGKGASRRLRRNVSMVPAVIYGGDKAPQSISLLAKDLAKLLENEAAFSHVLAVNVAGATENVVIKALQRHPAKGFVLHADFQRVVAGQKLTAHVPLHFINEATAVGVKQQGGEISHTINEVEVSCLPKDLPEFIEVDMAAVEVGQTVHMSDLKLPKGVELVALAHGNDLAVSNIHASRVKAEDEGAAE
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: HXA2B_DANRE
Sequence: MNYEFERETGFINSQPSLAECLTSFPPVGDAFQSSSIKSSTLSHSTLIPPPFEQTIPSLNPGSHPRHSRPKQNPNGSCPLPAASLPPEYPWMKEKKASKKNQTTSTAATTDPGPLYFSPQGSPEISDGGSGATRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKENHHGDGKPPSLEEAGGRGDGKSFFEQVANNVSGALLEREGYPFQQNTLTSQQSQNGHNSDSQSATVSPLGSNDKHLKHFPNPSPTVPICTTTMAPDCASAQDNGSPSALDVSLQDFNVFSNDSCLHLSDAVSPSLSESVDSPIGLTTEAFDFFSETLTTIDLQHLSY
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-A2b, Hox-A2.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family. Proboscipedia subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: LMX1A_HUMAN
Sequence: MLDGLKMEENFQSAIDTSASFSSLLGRAVSPKSVCEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPLETTCFYRDKKLYCKYDYEKLFAVKCGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCKGDYEKERELLSLVSPAASDSGKSDDEESLCKSAHGAGKGTAEEGKDHKRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRQQQQQQDQQNTQRLSSAQTNGGGSAGMEGIMNPYTALPTPQQLLAIEQSVYSSDPFRQGLTPPQMPGDHMHPYGAEPLFHDLDSDDTSLSNLGDCFLATSEAGPLQSRVGNPIDHLYSMQNSYFTS
What is the function of this protein?
Acts as a transcriptional activator by binding to an A/T-rich sequence, the FLAT element, in the insulin gene promoter.  Required for development of the roof plate and, in turn, for specification of dorsal cell fates in the CNS and developing vertebrae (By similarity).
What are the official names of this protein?
LIM homeobox transcription factor 1-alpha, LIM/homeobox protein 1.1, LMX-1.1, LIM/homeobox protein LMX1A.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACCA_STRZP
Sequence: MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAVVGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVTFINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRVWMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEIGLSSKELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YL045_MIMIV
Sequence: MYDKLPLELWVKITNYSQEFGLLLTNKNFFELLYLMKFETNIIEYVVENNLLDILRHIIFLKNINHPIIMENIIDIRCLEESLNASCKNGKLEIVKLLVDLGANIFHNENCAMMLASEYGHIEIVEYLVSKGSDVRADNDYAVIYASKNGHLEIVKYLVSQGCDVRSCDSYAVRLASEYGHLEIVKFLVKKGANYRALNHHAVIEASKNKHYEIVEFLMNYSTGITK
What are the official names of this protein?
Putative ankyrin repeat protein L45.
Protein: YK18_SCHPO
Sequence: MMTRMELRPLEIGFSKALTEVAPVTCQCECWDHNLCSSQASEMDLIYQSQDTHSCASKQDAVFQLLSETKIPVPNRYRKISHRLSTLSNKKTLKSQLDRFLSSSKKLHNDDVNRGDYCFLLSTPVECSASTNSHSYDCLWNFSCNSFPEYSSYSASETSSVASYSYYSGPNPATPSSSSCNLVNANSLDIYLNINNLKKSKSVPRLRGQFMEPVEHNHPLSKSLEEQSSFLEQSKDASSNLTACNRSGSSLSSNFYSSRLSKKTSLASLNKSRASLQHKIMSLSRNIIRRVFHKPEVHLDPSASILNLSSSHGESNLTNGLLCQNFKLFQDDWLMEDCAPDANFTLYTPLQPWEKRSVKPEIRRPRLNPNFFRVFVLEAQMRRAGKLSANTAGRAQLIYLPKPAVTFSTSPLHVEL
What is the function of this protein?
May have a role in meiosis and sporulation.
What are the official names of this protein?
Meiotically up-regulated protein PB1A10.08.
What are the subcellular locations of this protein?
Cytoplasm. Note=Barrier septum.
Protein: Y2411_MYCTO
Sequence: MRRVSLPNQLNETRRRSPTRGERIFGGYNTSDVYAMAFDEMFDAQGIVRGPYKGIYAELAPSDASELKARADALGRAFIDQGITFSLSGQERPFPLDLVPRVISAPEWTRLERGITQRVKALECYLDDIYGDQEILRDGVIPRRLVTSCEHFHRQAVGIVPPNGVRIHVAGIDLIRDHRGDFRVLEDNLRSPSGVSYVMENRRTMARVFPNLFATHRVRAVDDYASHLLRALRNSAATNEADPTVVVLTPGVYNSAYFEHSLLARQMGVELVEGRDLFCRDNQVYMRTTEGERQVDVIYRRIDDAFLDPLQFRADSVLGVAGLVNAARAGNVVLSSAIGNGVGDDKLVYTYVPTMIEYYLHEKPLLANVETLRCWLDDEREEVLDRIRELVLKPVEGSGGYGIVFGPEASQAELAAVSQKIRDDPRSWIAQPMMELSTVPTRIEGTLAPRYVDLRPFAVNDGNEVWVLPGGLTRVALVEGSRVVNSSQGGGSKDTWVLAPRASAAARELGAAQIVRSLPQPLCDPTVDASGYEPHDQQPQQQQQQQQQAFH
What are the official names of this protein?
Uncharacterized protein MT2484.
What is the protein family that this protein belongs to?
To Synechocystis PCC 6803 sll0335 and to M.tuberculosis Rv2567.
Protein: PLIN5_SHEEP
Sequence: MSEDEAAQAPGPSLSEQDQQSAVQRVAALPLIRATCTAVSEAYSAAKDRHPLLGSACRLAEHCVCDLTTRALDHAQPLLSHLQPQLATVNDLACRGLDKLEEKLPFLQQPSETVVTSAKGVVASSVTGMVGLARQGRRWSVELKRSVSHAMDVVLEKSEELVDHFLPMTEEELAALAAEAEGPEVGSVEEQRKHQGYFVRLGSLSTRLRHLAYEHSLGKLRQKKHHAQDTLAQLQETLELIHRMQCGVTPITPARPGKVHELWEDWSQRPLENGRRRHSQAELETLVLSRNLMRELQSTVDALETSVRGLPPSAQEKVAEVRRSVDALQAAFADARRFGDLPAAVLAEGRGSMARAHACVDELLELVVQAMPLPWLVGPFAPILVERPEPPPDLEALVDEVIGGPDPRWAHLDWPAQQRAWQAQHGEGTVLSGNIPEEEPEPPSRPKHTLMPELDF
What is the function of this protein?
Lipid droplet-associated protein that maintains the balance between lipogenesis and lipolysis and also regulates fatty acid oxidation in oxidative tissues.  Recruits mitochondria to the surface of lipid droplets and is involved in lipid droplet homeostasis by regulating both the storage of fatty acids in the form of triglycerides and the release of fatty acids for mitochondrial fatty acid oxidation.  In lipid droplet triacylglycerol hydrolysis, plays a role as a scaffolding protein for three major key lipolytic players: ABHD5, PNPLA2 and LIPE.  Reduces the triacylglycerol hydrolase activity of PNPLA2 by recruiting and sequestering PNPLA2 to lipid droplets.  Phosphorylation by PKA enables lipolysis probably by promoting release of ABHD5 from the perilipin scaffold and by facilitating interaction of ABHD5 with PNPLA2.  Also increases lipolysis through interaction with LIPE and upon PKA-mediated phosphorylation of LIPE (By similarity).
What are the official names of this protein?
Perilipin-5, Lipid storage droplet protein 5.
What is the protein family that this protein belongs to?
Belongs to the perilipin family.
What are the subcellular locations of this protein?
Lipid droplet. Cytoplasm. Mitochondrion. Note=Lipid droplet surface-associated. Exchanges between lipid droplets and the cytoplasm.
Protein: TPGS1_MOUSE
Sequence: MAALPVPLPPTKMAAVEKRRPAVAPAANFPDSGRTSVSQAAAAAESEEDFLRQLGVTEMLRAALLKVLEIRPEEPIAFLAHYFENMGLRSPTNGGAGEPPGQLLLQQQRLGRALWHLRLAHHSQRTAFNNNVSVAYECLSASGRKKKPGLDGRTYSELLKRVCRDGGAPEEVVAPLLRKIQCRDHEAVPLGIFRTGMLSCFVLLEFVARAGALFQLLEDPGQAVADRRVGQAVLDTLEGALSAGDMATAPTHYLEAGSRLGPDNLARALDRAASGRRPSVPMAREEFLEKAAALFIAKVKPVG
What is the function of this protein?
Subunit of the tubulin polyglutamylase complex (TPGC).  The complex mediates cilia and flagella polyglutamylation which is essential for their biogenesis and motility (PubMed:12242242, PubMed:12972506, PubMed:15890843).  May act in the targeting of the tubulin polyglutamylase complex.  Required for the development of the spermatid flagellum.
What are the official names of this protein?
Tubulin polyglutamylase complex subunit 1, PGs1, p32.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, flagellum basal body. Cell projection, axon. Cell projection, dendrite. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Associated with microtubules from neurites, centrosomes, basal bodies and axonemes.
Protein: NCAP_RABVH
Sequence: MDADKIVFKVNNRVVSLKPEIIVDQYEYKYPAIKDLKKPCITLGKAPDLNKAYKSVLSGMNAAKLDPDDVCSYLAAAMQFFEGTCPEDWTSYGILIARKGDKITPDSLVEIKRTDVEGNWALTGGMELTRDPTVSEHASLVGLLLSLYRLSKISGQNTGNYKTNIADRIEQIFETAPFVKIVEHHTLMTTHKMCANWSTIPNFRFLAGTYDMFFSRIEHLYSAIRVGTVVTAYEDCSGLVSFTGFIKQINLTAREAILYFFHKNFEEEIRRMFEPGQETAVPHSYFIHFRSLGLSGKSPYSSNAVGHVFNLIHFVGCYMGQVRSLNATVIAACAPHEMSVLGGYLGEEFFGKGTFERRFFRDEKELQEYEAAELTKTDVALADDGTVNSDDEDYFSGETRSPEAVYTRIMMNGGRLKRSHIRRYVSVSSNHQARPNSFAEFLNKTYSSDS
What is the function of this protein?
Encapsidates the genome in a ratio of one protein N per nine ribonucleotides, protecting it from nucleases.  If expressed without protein P it binds non-specifically RNA and therefore can bind it's own mRNA.  Interaction with protein P abolishes any non-specific RNA binding, and prevents phosphorylation.  The soluble N-P complex encapsidates specifically the genomic RNA, with protein N protecting the genome like a pearl necklace.  The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for viral transcription and replication.  Protein N binds protein P in the NC through a different interaction, and can be phosphorylated.  Subsequent viral replication is dependent on intracellular concentration of newly synthesized protein N.  During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).
What are the official names of this protein?
Nucleoprotein, NP, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the lyssavirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: NH114_CAEEL
Sequence: MTPQSSPSSSRDHVCLVCQDFASGYHYGVPSCVGCKTFFRRTIMKKQKYICQFEGNCPVDKTIRCACRYCRFEKCLSVGMDRNALQQNRDPIGYTKRTRRPKKELKTTSDCSSDEGASTPPSVSPLQLSPPPISPLLFQAAPLKPRRCILQTLAEREKCANDLRLSEYLPIRSLHEALCSKALLNDTAFLEKWGQPSERHQIFDLRFVNHDDYHYWHERDWFLLTEYAKTFDVFEALDYQDKAELVRHAAITVPVLVQVWNSPDYGPDTIVFPDGAYFDRTPEPTRPAGLNRKKYQMLDLVLKPFRDLQLDATEFAAFKAVTFLNPDADISLPARKLVNNERVRITKQLYGYMAMKDDVDTAIERFARLVLMGTSMSKMACESKEAVWIADFFENIGFSAFARQLFFGDTTSVVAHKL
What is the function of this protein?
Probable transcription factor which may have a role in detoxifying dietary metabolites arising from bacterial tryptophan metabolism (PubMed:23499532).  Required for fertility and involved in proper postembryonic germline development, especially germline stem cell (GSC) proliferation (PubMed:23499532).  Required for activation of the methionine/S-adenosylmethionine (Met/SAM) cycle in response to low levels of SAM (PubMed:33016879).
What are the official names of this protein?
Nuclear hormone receptor 114.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS3_LEIXX
Sequence: MGQKVNPYGFRLGITTDHVSRWFSDSTKKGQRYSDYLAEDVKIRTLLKTSLDRAGVSRIEIERTRDRVRVDIHTARPGIVIGRRGAEAERIRADLEKLSGKQIQLNILEVKNPEADAQLVAQGIAEQLAARVAFRRAMRKGLQGAQRAGSKGVRIQVSGRLGGAEMSRSEFYREGRVPLHTLRANIDYGFYEAKTTFGRLGVKVWMYKGDITNKELARVQANVKPSRERNDRPRRGGRGSNAPEASTVPAAAGVEA
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RL17_ONYPE
Sequence: MPFSKLGRNKSQRRALLRTLMTDLIVQEKIMITESKAKELQKLADKMVTLSKKNTLHTRRQAKRHLFDEKINDDTTVLQKLFKDISSKYLDRQGGYTRVIKTVPRRGDGAPMAIIAFV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: AL5AP_HORSE
Sequence: MDQETVGNVVLLAIVTLISVIQNGFFAHKVEHESKTQNGRSFQRTGTLAFERVYTANQNCVDAYPTFLVMLWSAGLLCSQVPAAFAGLMYLFVRQKYFVGYLGERRQSTPGYIFGKRIILFLFLMSLAGIFNYYLILFFGSDFENYIKTITTT
What is the function of this protein?
Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase).  Anchors ALOX5 to the membrane.  Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5.  Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes (By similarity).
What are the official names of this protein?
Arachidonate 5-lipoxygenase-activating protein, FLAP, MK-886-binding protein.
What is the protein family that this protein belongs to?
Belongs to the MAPEG family.
What are the subcellular locations of this protein?
Nucleus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: THIG_CORA7
Sequence: MLTIADTTFSSHLIMGTGGATSHEALERALVASGTELTTVAMRRHAGTRGGESIFDLLRRLDIAPLPNTAGCRTAREAVLTARMAREALGTTWVKVEVIADEHTLLPDVVETLDATELLAAEGFTVLAYTSDDPVAAQRLEDAGAAAVMPLGAPIGTGLGILNPHNLELICSRASVPVLVDAGIGTASDAALAMELGCSGVLLASAVNRCQNPEAMATAMRHAVEAGRLARSAGRIPEREHAQASSTFEGLASWADQVL
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LAC16_ARATH
Sequence: MEIPRRFCICVLTFFVFVLLSPTTVHSIIRHYKFNVMTNTTKLCSSKPIVTVNGQFPGPTIVAREGDTILIKVVNHVKYNVSIHWHGIRQLRTGWADGPAYITQCPIQPGQNYLHNFTLTGQRGTLWWHAHILWLRATVHGAIVILPKLGVPYPFPKPYKEKTIVLSEWWKSDVEELINEASRIGTAPSASDAHTINGHSGSISNCPSQSSYGLPVRAGKTYMLRIINAALNEELFFKIAGHVLTVVEVDAVYTKPYKTDTVFIAPGQTTNVLLTANANAGSNYMVAATTFTDAHIPYDNVTATATLHYIGHTSTVSTSKKTVLASLPPQNATWVATKFTRSLRSLNSLEYPARVPTTVEHSLFFTVGLGANPCQSCNNGVRLVAGINNVTFTMPKTALLQAHFFNISGVFTDDFPAKPSNPYDYTAPVKLGVNAATMKGTKLYRLPYNATVQIVLQNTAMILSDNHPFHLHGFNFFEVGRGLGNFNPEKDPKAFNLVDPVERNTVGVPAGGWTAIRFIADNPGVWFMHCHLELHTTWGLKMAFVVDNGHGPDQSLLPPPADLPKC
What is the function of this protein?
Lignin degradation and detoxification of lignin-derived products.
What are the official names of this protein?
Laccase-16, Benzenediol:oxygen oxidoreductase 16, Diphenol oxidase 16, Urishiol oxidase 16.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: REP_MSVSE
Sequence: MTSSSSNRPFSHRSPNTFLTYPQCPEQPEIISQRIWDLCSHWTPLYIICAREAHRDGNQCLHALIQTEKPVRTTDSRFFDIDGFHPNIQSAISPNKVRDYITKEPLALFERGTFIPRKKSFLGNSSKGNSDKKPSKDEIMRDIISHATSKQEYLSMVQKSLPYDWSTKLQYFEYSANKLFPDIQEEFINPHPTSEPDLLCNESIKDWLQPNIYQADYGTRKRSLYIVGPTRTGKSTWARSLGRHNYWQNNVDWSSYNEDTIYNIVDDIPFKYCPCWKQLVGCQKEFVVNPKYGKKKKVQMKSKPTIILANSDEDWMKEMTPGQLEYFEANCMIYVMQPGEKWYSPPELPPTEEV
What is the function of this protein?
Essential for the replication of viral ssDNA.  The closed circular ssDNA genome is first converted to a superhelical dsDNA.  Rep binds a specific region at the genome origin of replication.  It introduces an endonucleolytic nick within the conserved sequence 5'-TAATATTAC-3' in the intergenic region of the genome present in all geminiviruses, thereby initiating the rolling circle replication (RCR).  Following cleavage, binds covalently to the 5'-phosphate of DNA as a tyrosyl ester.  The cleavage gives rise to a free 3'-OH that serves as a primer for the cellular DNA polymerase.  The polymerase synthesizes the (+) strand DNA by rolling circle mechanism.  After one round of replication, a Rep-catalyzed nucleotidyl transfer reaction releases a circular single-stranded virus genome, thereby terminating the replication.  Displays origin-specific DNA cleavage, nucleotidyl transferase, ATPase and helicase activities.  Acts as an inhibitor of C-sense gene transcription (By similarity).
What are the official names of this protein?
Replication-associated protein, Rep.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae Rep protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: RL22_CAMJE
Sequence: MSKALIKFIRLSPTKARLIAREVQGMNAELAMASLKFMPNKGAKYIANAISSAVANGGFEANEVIVKSCRVDAAAVLKRFRPRARGSASRIRKPTSHILVEVAKAEVKSEEKKTVAKKTTTTKAPAKKTTSTKKATVKKES
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: DML1_ASPCL
Sequence: MHEIITLQLGQRANYLATHFWNLQESYFTYNEGEESPIDHDVHFRAGVGADGSETYTPRTLIYDLKGAFGTLRKQNALYELSTDSEYGQGLWDGKEVIQKQTPIIPSEYQLNLEQGLPAPALSSETVRYWSDYNRVFYHPRSIIQLNDYELNSKIMPFEDWDVGEDLFNDLDKEHDLLDRDVRPFAEECDQLRAFQLFAGSDDAWGGFAAKYLDRIRDEYGKKAVWVWAMEGGSKLQRRNQLKRDINKARSIHAMAPQSSLYVPIKDPPGHVPSTINLDAQSEWQTSALISSALETVTLPTRLRPYHDFETSLAGEDGMHKIFELQSTILPEDKTPTGAAGGNEASTEATSKVKTEFDMDFTYDDPQNRNSHIFNQVQITRGYSPVTDEASIREDLGLSRKKRFYNSEPMLESFYTPLAFPTLDSFPHNLFPVKESNAKINILASLTASSRTAGKLRAMEVVARRVVGVDERENLVNGLGEIRESYETGWMSDSDFDDD
What is the function of this protein?
Involved in the partitioning of the mitochondrial organelle and mitochondrial DNA (mtDNA) inheritance.
What are the official names of this protein?
Protein dml1.
What is the protein family that this protein belongs to?
Belongs to the misato family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL30_ANASK
Sequence: MAAIKVKLVRGLAGCPWPHRVIVEGLGLKKRESTKLLPDTPQTLGMIAKVSYLVEWERVDAAPPPGRKARKAAARS
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.