PharMolix/UniProtQA huggingface dataset:
Protein: HEM1_PROM4
Sequence: MNIAVVGLSHRTAPVEVREKLSISDDNIPSAFNTLNTNDQIIEVSILSTCNRLEIYSFVKNSDNGVKAIKDFLCKHSGLGIDELDPHLFSYDQAEAVKHVMRVAGGLDSLVLGEGQILSQVKKMVRLGQENHSMGPILNRLLTQAVSTGKRVRSETNLGTGAVSISSAAVELAQLKLGQSEGKDELMSLEREKVSIVGAGRMSRLLIQHLQSKGCSKLKLINRTFQRAEALALDFPDVDIHCQLLDDLDESLRNSTLIFTSTAAENPIIDAARLKEVVRDETLRLIDIGVPRNISSDVKGLTGFEAHDVDDLQEVVSRNQEARQQIALEAEALVDEEGRIFLEWWASLEAVPTINLLRSSLESVRKEELQKALSRMGPDFSARERKVVEALSKGIINKILHTPVTNLRAPQTSSNRKISLEVIETLFELGVSESE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: LFTR_SHEB5
Sequence: MKSLSFLNHEFEAFPSPELALTDPNGLLAIGGDLRPERLLSAYYNGIFPWFNSDDPILWWSPDPRAVFIPGEIHISTSLRKYLKKQPWRITINHAFTDVMAGCAQPREKQSGTWITQEIQMAYRELHHTGHAHSIEVWEGERLIGGLYGLAIGQVFCGESMFHRKTNASKAAVAALQQHLLKMGFKLIDAQVMNPHLESLGAKAIKRIDFITLLSELRNNPVDPTTWTTKEVILELE
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THY_BPT5
Sequence: MQQYLKILTDVILLGEPRNDRTGTGTVSIFDSYAKFDLREGFPAVTTKRLAWKSVVGELLWFLSGSTNLHDLRVFTFGRDEGQWTIWTPNYEDQAISMGYDKGNLGPVYGKQWRNFGGRDQILELIEGLKNNPHGRRHLVSAWNVAELDKMALPPCHYGFQCYVSNDGYLDLKWTQRSVDCFLGLPFNIASYALLTHILAKLTGLKPRYLIFSGGDTHIYNDHMEQVEEQVKRKPRPLPTLVMPEFVDLYDLLENNTAAWSFHLEGYDPHPALKAKMSS
What is the function of this protein?
Sythesizes the thymine necessary for the viral DNA replication.
What are the official names of this protein?
Probable thymidylate synthase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family.
Protein: SAHH_XANAC
Sequence: MNAVTKITPHTDYKIADISLADWGRKELDIAEHEMPGLMSIRRKHAQTKPLKDVRITGSLHMTIQTAVLIETLKDIGADVRWASCNIFSTQDHAAAAIAATGTPVFAWKGETLEEYWDCTLDALTFTLPDGTLTGPELVVDDGGDVTLLIHKGYELENGSTWVDEPASSHEEGVIKALLKRVAVERPGYWGRVVKDWKGVSEETTTGVHRLYQIAEAGKLLIPAINVNDSVTKSKFDNLYGCRESLADGLKRAMDVMLAGKVAVVCGYGDVGKGSAASLRAYGARVIVTEIDPICALQASMEGFEVNTIESTLGRADIYVTTTGNKDIITVEHLQAMKDQAIVCNIGHFDNEIQVDALKALKDVQKINIKPQVDKYVFPNGNAIFLLADGRLVNLGCATGHPSFVMSNSFANQTLAQIDLWEKRDTYEKKVYILPKHLDEEVARLHLEKIGVKLTTLTKDQADYLGVDVAGPYKPDHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COPZ_STAA8
Sequence: MSQEILNVEGMSCGHCKSAVESALNNIDGVTSADVNLENGQVSVQYDDSKVAVSQMKDAIEDQGYDVV
What is the function of this protein?
Chaperone that serves for the intracellular sequestration and transport of Cu(+).  Delivers Cu(+) to the copper-exporting P-type ATPase A (CopA) (By similarity).
What are the official names of this protein?
Copper chaperone CopZ.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FEN1_LODEL
Sequence: MGVKGLNQLIKEHSPHAYKEFELKNLFGRKVAIDASMCLYQFLIAVRQSDGQQLTNDEGETTSHLSGIFYRTIRMVENNIKPVYVFDGKPPVLKGGELEKRLLKREEAQKQIDNLKDDASVSDMTKYQKRLVRVSRDQNDEAKKLLELMGIPYVNAPCEAEAQCAELARGGKVFAAASEDMDTLCYEPPQLLRHLTFAEARKMPIDQITYKEAIQGLDMTKEQFIDLCILLGCDYCETIKGVGPVTAYKLIKEHGSLDNIVKYLQENPDKTKYKVPENWPYNEARQLFMKPEVLPALEVELKWKEPDLDGLIEYMVKNKGFSEDRIRSGAEKLKKGLKAGIQGRLDGFFTVVPKYSNTSPLGKDDKKRKTNDKKGAAAKKTKRR
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: VPS10_DEBHA
Sequence: MRIELRSWSSIAFLFTLFIAYVVSESNFKPDIKLTKEGEIAKEYNYFDDSSNILVLRKDKLAISFDDGVSWKNVKETENERVIRYQFDPFNNNRAFAFTIDKFQYVTNDKGETWSKFEIYDPKNEKEHLTLNSIPHILFNAKNPDLAIFVVYHCPEDKKISNQCVNYHFLTTDGFKSNPKSLQTDASICTFAKSTKSYDVGKDETIYCSRNKLNSFGHIVESYIVASDDFFKTESKINHALAKSGSIIDIRVLQNFAIVVVQNDKFNTKSKVSLLVSKDGKNFNEADLKVDISYGIMTFLESSSSSIFLAVMDYSNSFRKFSLSTVYSSDSSGLSFSKVLDKVQGGSIQKVETIDGVWLANIADEIKDNKGKSKTLLDMLMGGGIDKNIKSRISYNDGEDWNLLKINNDGSCTTESECSLHLLNPTEKSGDGKFVTGPTPGILLSVGNKGSKLEKDINRMNTWISRDGGISWDFALDEPCLFSFGDQGNIIVAIPYYGKNKMNSSNMYFSLDQGKSWENVALEIPIFPLTLTTTVDGTSQRFILSGLIDSTPKDKADYSFAETLYAIDFSKAFGGKKCDSKKDFEDIYTRLDPSNDKPICIYGHKEKFRRRKQNSQCFVNELFEDVKVYDDPCECTVIDFECASGFSRSKEKECKPDKKKLANICRDKKSKKISLPDKALASGNKCKNPKEAAKEFVKTKEFKCSDYLDEDDKDKNKGNKHDIVSTFNEFDSELQQYTYVEQGETYSGENIILRTKANVAYASNNGGVEFVKIPVSDEIVTYYPGLVPGQVILITDSEKFYFSIDGGNTFQKKTAPAKPNVIGARIISFDKKDTEKFIWYSSENCDNPFSRDCSLVAYITEDGGENFQKLKEDVRSCDFVADVFEDVSDEIKNMIYCTVEDKSSRKLMLLSSTDYFKQSKKVFDNVVGYAITGNFLVAATIDDAEQSLKAKVTVDGQIFADADFPPDFHVDSQQAYTVLDSASKAIFIHVTTNNENGHEFGSILKSNSNGTSYSLTLDKVNRNRIGYVDYDRIEGIEGVIVSNIVANDHSKDRKKLKTQITHNDGGEWSYITPPVIDSKGKKYKCNGKSLSKCSLNLHGFTERADYRDTFSSASAIGLMMAVGNVGEYLEDFDKCSTFISRDGGITWKEIKKGVYMWEYGDRGTILVLVNAEKTTDKLMYSLDEGDTWHDYKFAEEPIDVLDLATVPSDTSRKFLIFGKSDRKMVSYSIDFTNIHKRQCQLDLDNPNDDDFEYWSPTHPSTPDNCLFGREAKYLRRAIGHDDCFIGSAPLIEGFKVTRNCSCTRKDYECDYNFFRDSDDTCKLVKGLSPSNRKKEMCKKENAFEYFEPTGYRKIPLSTCVGGKNFDTWKVHPCPGKQKEFNKHHGKELNSGSLLAVIGIPIAVFLLATWFVYERGIRRNGGFKRFGQIRLDLDDDDFHPIENNEVDKAINKIVKGGIVIVAASIAGFKTLRKVDRMLFDKVTSSLFRRRPGHRNYVHVPEMDEEEELFGNFRDNYEEELEEGTNNINEDFNDEPNDYEYEEETNDEVDSRLFNIDDQSDEELQSATPEDN
What is the function of this protein?
Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A.  Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment (By similarity).
What are the official names of this protein?
Vacuolar protein sorting/targeting protein 10, Carboxypeptidase Y receptor, CPY receptor, Sortilin VPS10, Vacuolar carboxypeptidase sorting receptor VPS10.
What is the protein family that this protein belongs to?
Belongs to the VPS10-related sortilin family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Prevacuolar compartment membrane; Single-pass type I membrane protein. Note=Cycles between the Golgi apparatus and the prevacuolar compartment.
Protein: RK2_LEMMI
Sequence: MAIHLYKTSTPSTRNGAVDRKVKSNPRNNLIYGQHRCGKGRNARGIITAGHRGGGHKRLYRKIDFRRNEKDIYGRIVTIEYDPNRNAYICLIHYGDGEKRYILHPRGAIIGDTIVSGTEVPISMGNALPLTDMPLGTAIHNIEITLGKGGQLARAAGAVAKLIAKEGKSATLRLPSGEVRLISKNCLATVGQVGNVGVNQKSLGRAGSKCWLGKRPVVRGVVMNPVDHPHGGGEGRAPIGRKRPMTPWGYPALGKRSRKKKRYSDRFILRRRK
What are the official names of this protein?
50S ribosomal protein L2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PURA_BRUA2
Sequence: MANVVVVGSQWGDEGKGKIVDWLSERADVIVRYQGGHNAGHTLVIDGVSYKLSLLPSGLVRGKLSVIGNGVVVDPHHFVAEVEKLRGQGIDVTPDVLRVAENAPLILSIHRELDAMREGSNSGLKIGTTKRGIGPAYEDKVGRRAIRVIDLTEPETLRPKVERLLAHHNSLRRGMGLEEIAVETILTELTSVADQILPYIDQVWRVLDERRKAGARILFEGAQGALLDNDHGTYPFVTSSNTVAGQAAAGSGLGPTAIGYVLGITKAYTTRVGEGPFPTELNDEIGEFLGTKGHEFGVVTGRKRRCGWFDAVIVRQTVRTSGINGIALTKLDVLDGLEEIKICVAYELDGKRIDYLPSSMGAQARVKPIYETLPGWSETTAGARSWNDLPAQAVKYVRHIEELIGAPVAMLSTSPEREDTILVTDPFHD
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURC_PSEPW
Sequence: MVESQKAMPQPKMGRIHRIHFVGIGGVGMCGIAEVLLNLGYEVSGSDLKVSPVTQRLESFGAEIFVGHRAENAAHADVLVVSSAINPANPEVATALERRIPVVPRAEMLAELMRYRHGVAVAGTHGKTTTTSLLASVFAAGGLDPTFVIGGRLTAAGTNAQLGTSRYLIAEADESDASFLHLQPMVAVVTNIDADHMATYEGDFNKLKKTFVEFLHNLPFYGLAVMCLDDPVVREILPQVKRPTVTYGFCEEADIRAINVSQKGMQTHFTVLRRDREPLEVSVNMPGNHNVLNALATIAIATDEGISDEAIVQGLSGFQGVGRRFQVYGELPVEGGSVMLVDDYGHHPTEVAAVIKAVRGGWPSRRLVIVYQPHRYSRTRDLYDDFVQVLGDANVLLLMEVYPAGEEPIPGADSRQLCHSIRQRGKLDPIYIERGAELAPLVKPLLRAGDILLCQGAGDVGGLAPQLMKSPLFAGAKQEKSK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_BACCZ
Sequence: MAAKWEKLEGNVGVLTIEVDAKEVNNSIDAAFKKVVKTINVPGFRKGKMPRPLFEQRFGIESLYQDALDIILPKAYGEAIDEAGIFPVAHPEIDIEKFEKNANLIFTAKVTVKPEVKLGEYKGLAVEKVETTVTDEDVENELKSLQERQAELVVKEEGTVENGDTAVIDFEGFVDGEAFEGGKGENYSLAIGSGTFIPGFEEQVIGLKSGESKDVEVSFPEEYHAAELAGKPATFKVTVHEIKTKELPELNDEFAKEADEAVATLDELKAKLRTNLEEGKKHEAEHKVRDEVVELAAANAEIDIPEAMIDTELDRMVREFEQRLSQQGMNLELYYQFTGTDADKLKEQMKEDAQKRVRINLVLEAIIEAENIEVTEEEVTAEVEKMAEMYGMPVDAIKQALGSVDALAEDLKVRKAVDFLVENAA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: RL17_BORBR
Sequence: MRHGNGLRKLNRTSSHRLAMFRNMAVSLITHEAIKTTLPKAKELRRVIEPLITLGKEPTLANKRLAFARLRDRDAVVKLFAEIGPRYANRNGGYTRVLKMGFRQGDNAPMAFMELVDRPEVDASEADSDAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: TADA1_RAT
Sequence: MATFVSELEAAKKNLSEALGDNVKQYWANLKLWFKQKISKEEFDLEAHRLLTQDNVHSHNDFLLAILTRCQILVSTPEGAGSLPWTGGSAAKPGKPKGKKKLSSVRQKFDHRFQPQNPLSGAQQFVAKDPQDDDDLKLCSHTMMLPTRGQLEGRMIVTAYEHGLDNVTEEAVSAVVYAVENHLKDILTSVVSRRKAYRVRDGHFKYAFGSNVTPQPYLKNSVVAYNNLVEGPPAFPAPCASQNPASHPHTDDAEQQAAFLLACSGDTLPASLPPVNMYDLFEALQVHREVIPTHTVYALNIERIIMKLWHPNHEELQQDKVHRQRLAAKEGLLLC
What is the function of this protein?
Probably involved in transcriptional regulation.
What are the official names of this protein?
Transcriptional adapter 1, Transcriptional adapter 1-like protein.
What is the protein family that this protein belongs to?
Belongs to the TADA1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RTCA_SHIDS
Sequence: MKRMIALDGAQGEGGGQILRSALSLSMITGQPFTITGIRAGRAKPGLLRQHLTAVKAATEICRATVEGAELGSQRLVFRPGTVRGGDYRFAIGSAGSCTLVLQTVLPALWFADGPSRVEVSGGTDNPSAPPADFIRRVLEPLLAKIGIHQQTTLLRHGFYPVGGGVVATEVSPVASFNTLQLGERGNIVQMRGEVLLAGVPRHVAEREIATLAGSFPLHEQYIHNLPRDQGPGNTVSLEVESENITERFFVVGEKHVSAEVVAAQLVKEVKRYLASPAAVGEYLADQLVLPMALAGAGQFTVAHPSCHLLTNIAVVERFLPVRFTLAETNGVTRVMITKLTD
What is the function of this protein?
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA.  The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product.  The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
What are the official names of this protein?
RNA 3'-terminal phosphate cyclase, RNA cyclase, RNA-3'-phosphate cyclase.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALR_STRMU
Sequence: MIASYHRPTTALVHLDRIKFNIEQVQHHIPKSAKTFAVVKANAYGHGAVQVAQAIQKQVDGFCVSNLDEALELRQAGLNDFILILGVLLPEEVALAKKENITITVADLDWFDKVQTENIDLAGLSVHVKVDSGMGRIGVRSTAEANQLIAGLQKAGATVNGIFTHFATADEASTVKFSQQLEMFTTLISQLDYKPQTVHASNSATSIWHSDTVMNAVRLGIVMYGLNPSGNALELPYEVKPALELTSALVQVKEVQAGDTVGYGATYTASQAEIIGTVPVGYADGWTRDLQGFHVLVNGHYCEIVGRVSMDQITIRLPKAYPLGTKVTLIGQDGHETISATDVAEKRETINYEVLCLISDRVPRKYDKKFS
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: MEND_CROS8
Sequence: MSTSTFNRRWAGVILEALSRHGVRHLCIAPGSRSTPLTLAAAQHPAFTPHTHFDERGLGHLALGLAKASGEPVAVIVTSGTAVANLYPAVIEAGLTGEKLVVITADRPPELIDCGANQAIRQHSIFGSHPAATLDLPRPTPSIPAAWLISAIDETMGALAAGALHINTPFAEPLYGELDETDLTWQQAPGEWWQTTTPWLRYEKIQAVSAQADWPFWREQRGVVLAGRLTAQEGEAVAQWAARLGWPLIGDVLSQTGQPLPCADLWLAHPRAAALLAQAPVVVQFGGSLTGKRVLQWQSECRPQEYWVVDPLPGRLDPAHHRGRRIVADISAWLEQHPAHPMMPWDEPLEGLAAQTQRIVARELTEWGEAQVAHRLPELLPPDGQLFLGNSLTVRLVDALAQLPAGYPVYGNRGASGIDGLVSTAAGVQRATGKPTLAVLGDLSTLYDLNALALLRDAPAPFVLIVVNNNGGQIFSMLPTPAREREKFYCMPQNVCFAPAAAMFSLNYDAPESLAALKEAVTRAWRSSVATVIELRVPETAGAQVFSRLLKAVCA
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: RHAA_ECOL5
Sequence: MTTQLEQAWELAKQRFAAVGIDVEEALRQLDRLPVSMHCWQGDDVSGFENPEGSLTGGIQATGNYPGKARNASELRADLEQAMRLIPGPKRLNLHAIYLESDTPVSRDQIKPEHFKNWVEWAKANQLGLDFNPSCFSHPLSADGFTLSHADDRIRQFWIDHCKASRRVSAYFGEQLGTPSVMNIWIPDGMKDITVDRLAPRQRLLAALDEVISEKLNPAHHIDAVESKLFGIGAESYTVGSNEFYLGYATSRQTALCLDAGHFHPTEVISDKISAAMLYVPQLLLHVSRPVRWDSDHVVLLDDETQAIASEIVRHDLFDRVHIGLDFFDASINRIAAWVIGTRNMKKALLRALLEPTAELRKLEAAGDYTARLALLEEQKSLPWQAVWEMYCQRHDTPAGSEWLENVRTYEKEILSRRG
What is the function of this protein?
Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
What are the official names of this protein?
L-rhamnose isomerase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y132_THEON
Sequence: MVRYPAVAGSFYPGDETLIEMLEKFFRDLGEHGSERKITAGVVPHAGYVFSGYTASRTFKAIYEDGLPETFVILGPNHTGIGSPIAVYPSGSWLTPLGEIEVDSEMAKTIAKLSGIADLDELAHKYEHSIEVQLPFIQYLAEKARTDVRIVPITLGIQDEEVVEDLGKAIYEAANELDRDVVIIASTDFMHYGPAYGYVPFRARADELPHRVKEWDFRVIQKILDFDVKGMFGELRKMDHTMCGPGGVGTAIVYSRLAGALEAELLHYTTSFEVSRSTDAIVGYASIVFRK
What are the official names of this protein?
MEMO1 family protein TON_0132.
What is the protein family that this protein belongs to?
Belongs to the MEMO1 family.
Protein: TPPC3_RAT
Sequence: MSRQANRGTESKKMSSELFTLTYGALVTQLCKDYENDEDVNKQLDRMGYNIGVRLIEDFLARSNVGRCHDFRETADVIAKVAFKMYLGITPSITNWSPAGDEFSLILENNPLVDFVELPDNHSALIYSNLLCGVLRGALEMVQMAVEAKFVQDTLKGDGVTEIRMRFIRRIEDNLPAGEE
What is the function of this protein?
May play a role in vesicular transport from endoplasmic reticulum to Golgi.
What are the official names of this protein?
Trafficking protein particle complex subunit 3.
What is the protein family that this protein belongs to?
Belongs to the TRAPP small subunits family. BET3 subfamily.
What are the subcellular locations of this protein?
Golgi apparatus, cis-Golgi network. Endoplasmic reticulum.
Protein: EFP_MYCTU
Sequence: MATTADFKNGLVLVIDGQLWTITEFQHVKPGKGPAFVRTKLKNVLSGKVVDKTFNAGVKVDTATVDRRDTTYLYRDGSDFVFMDSQDYEQHPLPEALVGDAARFLLEGMPVQVAFHNGVPLYIELPVTVELEVTHTEPGLQGDRSSAGTKPATLQTGAQINVPLFINTGDKLKVDSRDGSYLGRVNA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity).
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WNT9B_MOUSE
Sequence: MRPAPALALAALCLLVLPAAAAAAAYFGLTGREVLTPFPGLGTAAAPAQAGAHLKQCDLLKLSRRQKQLCRREPGLAETLRDAAHLGLLECQFQFRQERWNCSLEGRTGLLQRGFKETAFLYAVSAAALTHALARACSAGRMERCTCDDSPGLESRQAWQWGVCGDNLKYSTKFLSNFLGPKRGSKDLRARADAHNTHVGIKAVKSGLRTTCKCHGVSGSCAVRTCWKQLSPFRETGQVLKLRYDTAVKVSSATNEALGRLELWAPAKPGGPAKGLAPRPGDLVYMEDSPSFCRPSKYSPGTAGRVCSRDSSCSSLCCGRGYDTQSRMVVFSCHCQVQWCCYVECQQCAQQELVYTCKR
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors (Probable).  Functions in the canonical Wnt/beta-catenin signaling pathway (PubMed:22461561, PubMed:16054034, PubMed:17537789).  Required for normal embryonic kidney development, and for normal development of the urogenital tract, including uterus and part of the oviduct and the upper vagina in females, and epididymis and vas deferens in males (PubMed:16054034).  Activates a signaling cascade in the metanephric mesenchyme that induces tubulogenesis (PubMed:16054034, PubMed:17537789).  Acts upstream of WNT4 in the signaling pathways that mediate development of kidney tubules and the Muellerian ducts (PubMed:16054034).  Plays a role in cranofacial development and is required for normal fusion of the palate during embryonic development (PubMed:16054034, PubMed:22461561, PubMed:25257647).
What are the official names of this protein?
Protein Wnt-9b, Protein Wnt-14b, Protein Wnt-15.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Secreted.
Protein: NHAA_ECOK1
Sequence: MKHLHRFFSSDASGGIILIIAAVLAMIMANSGATSGWYHDFLETPVQLRVGTLEINKNMLLWINDALMAVFFLLVGLEVKRELMQGSLASLRQAAFPVIAAIGGMIVPALLYLAFNYADPITREGWAIPAATDIAFALGVLALLGSRVPLALKIFLMALAIIDDLGAIIIIALFYTNDLSMASLGVAAVAIAVLVVLNLCGVRRTGVYILVGVVLWTAVLKSGVHATLAGVIVGFFIPLKEKHGRSPAKRLEHVLHPWVAYLILPLFAFANAGVSLQGVTLEGLTSILPLGIIAGLLIGKPLGISLFCWLALRLKLAHLPEGTTYQQIMAVGILCGIGFTMSIFIASLAFGSVDPELINWAKLGILVGSISSAVIGYSWLRVRLRPSV
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UBE2W_HUMAN
Sequence: MASMQKRLQKELLALQNDPPPGMTLNEKSVQNSITQWIVDMEGAPGTLYEGEKFQLLFKFSSRYPFDSPQVMFTGENIPVHPHVYSNGHICLSILTEDWSPALSVQSVCLSIISMLSSCKEKRRPPDNSFYVRTCNKNPKKTKWWYHDDTC
What is the function of this protein?
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins (PubMed:20061386, PubMed:21229326).  Specifically monoubiquitinates the N-terminus of various substrates, including ATXN3, MAPT/TAU, POLR2H/RPB8 and STUB1/CHIP, by recognizing backbone atoms of disordered N-termini (PubMed:23560854, PubMed:23696636, PubMed:25436519).  Involved in degradation of misfolded chaperone substrates by mediating monoubiquitination of STUB1/CHIP, leading to recruitment of ATXN3 to monoubiquitinated STUB1/CHIP, and restriction of the length of ubiquitin chain attached to STUB1/CHIP substrates by ATXN3.  After UV irradiation, but not after mitomycin-C (MMC) treatment, acts as a specific E2 ubiquitin-conjugating enzyme for the Fanconi anemia complex by associating with E3 ubiquitin-protein ligase FANCL and catalyzing monoubiquitination of FANCD2, a key step in the DNA damage pathway (PubMed:19111657, PubMed:21229326).  In vitro catalyzes 'Lys-11'-linked polyubiquitination.  UBE2W-catalyzed ubiquitination occurs also in the presence of inactive RING/U-box type E3s, i. e.  lacking the active site cysteine residues to form thioester bonds with ubiquitin, or even in the absence of E3, albeit at a slower rate (PubMed:25436519).
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 W, E2 ubiquitin-conjugating enzyme W, N-terminal E2 ubiquitin-conjugating enzyme, N-terminus-conjugating E2, Ubiquitin carrier protein W, Ubiquitin-conjugating enzyme 16, UBC-16, Ubiquitin-protein ligase W.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: RPIA_ROSS1
Sequence: MDDNLYRQRAAEHALRHVESGMTIGLGTGSTATFMLYGLAARLADGRLQRVTGVPTSEVTAALARELGIPLTTLDRQPHLDLALDGADEIDPQLRLIKGLGGAMLREKIVAASAARFVVMAAVSKCVERLGERSPLPVEVVAFGLPLCARRLKALGGAPALRRDRSGAPFVTDEGNLILDCNFGIIADPEALAASICAIPGVVAHGLFLGMASLAVIAGPDGIVELHAPSARQ
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: DNLJ_POLNS
Sequence: MSSNSPTNLAERYAFLQAELARLEHAYYVLDNPLLPDIEYDRLYRELLDIEAVHPEWVTSESLSQRVGGAALKEFDSVTHAVPMLSLNNAFEDAELIAFDRRCREVLHAEHMAYAGELKFDGLAISLRYENGLLVTAATRGDGASGEDVTANIKTIRAIPLKLTRKNIPQVLEVRGEVFMYLKDFEKMNRQAAELGEKEFANPRNAAAGSLRQLDSKITAKRPLSFFAYGLGALEPQSWLPKTHEELLNAYIELGLPVCSERKVLHSVQEILAFYSEIDDKRDSLPYDIDGVVYKVNSFAEQAKLGFASRAPRFALAHKYPAQEALTTVLGIDVQVGRTGAITPVARLAPVEVGGVTVTNATLHNEDEIKRKDVRIGDTVSVRRAGDVIPEVVSVIKDRRPADAKEFQMPSRCPVCDSHIERLADEAVARCSGGLFCGAQRKQALIHFAHRRAMDIEGLGEKIVDQLVDQNLVRTPADLYRLGFTALANLERMGEKSADNLIKAINQSRNTTLARFIFALGIRHVGETTAKDLANHYQSMHALMDAGVEDLLTVKDVGPVVADSITSFMQEAHNREVIEQLLASGMRLAVEEKVISAAVAGKTFVLTGTFPTMTRDEAKDLLEKAGAKVAGSVSKKTDYVVAGTDAGSKLTKAEELGVPVIDEAAMLDLLK
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.