PharMolix/UniProtQA huggingface dataset:
Protein: NOP16_CANAL
Sequence: MTSVRKRKMARSSVKKNTRRTKDKQRNINIHSNPIIEANWDKSLTLKQNYKRLGLRAKLGRSAGGDERKVESLSELQAKREKNQKNQSKHVPTVSEIENLDDPSRIPEGEARLIRDPETNEVIKVIYGTMKVDDKDESEEEIENPSVIKQLEEYAEKNSKIKKERHQSERENDWIKSLYEKYGDDYDKMKWDKKLNIYQQSAGDLKRRIIKWKKANGI
What is the function of this protein?
Involved in the biogenesis of the 60S ribosomal subunit.
What are the official names of this protein?
Nucleolar protein 16.
What is the protein family that this protein belongs to?
Belongs to the NOP16 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: HEM12_ANADF
Sequence: MLVAVGLNQKGATVADREVLALPAEGFQSTLAEYAALDAVDEIAVMSTCYRVEIYAATRCPAAATLSLRQALNARAGRELPLFELHGEEAYRHLVRVASSLESAILGEPQILGQVKEAFQRSIDQGVAAKELTSVLNRALSAAKRVRTDTAIGRAGISWGHAAATLAEKVLGKMQGRRVVVVGAGEMARLSAQHLRDQGARIVVLNRTLVNGEALAREVGGVARPLEALGEELAQADVVVSAAPVAPDAFQPEAMAELSRSRKRPIVLVDLAVPRAIPAATGAIRDVYLCDVDDLDRVMKAAMSERAAAVADADRIIAEEVGKFVRAEAERRAAPLIQEMRTRASAIAREEVERTLRRLGEDPEVERRLEAMAGSIVSKILHAPSARLRQAVCDGCSGEALVSAAVEIFELSADIRVHRGNAA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase 2, GluTR 2.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: Y03B_BPT4
Sequence: MKFSTFDINDEFIANIDYTEEDSRYVGIIYITSKTAQGVVCMAEFDEYFLDYDDMIEWSKRYIKRNLL
What are the official names of this protein?
Uncharacterized 8.2 kDa protein in Gp46-Gp47 intergenic region, ORF G.
Protein: CSPLB_ORYSJ
Sequence: MFSAKARWIVAVVLRVAAAGAAAVAAVLMAMSHDEVIVYGMEVQAKFRYTPSLVFFVAANAAVSACSLVVLLVPSSTSKLAARLLLMADVVLGMVLAGAFAAAGAMAELGKNGNSHAGWIAICVQVPLFCDRVRSALVAGSATIVLYYLMLMYSIYTLPMFP
What are the official names of this protein?
CASP-like protein 1C1, OsCASPL1C1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RIBB_ECOHS
Sequence: MNQTLLSSFGTPFERVENALAALREGRGVMVLDDEDRENEGDMIFPAETMTVEQMALTIRHGSGIVCLCITEDRRKQLDLPMMVENNTSAYGTGFTVTIEAAEGVTTGVSAADRITTVRAAIADGAKPSDLNRPGHVFPLRAQAGGVLTRGGHTEATIDLMTLAGFKPAGVLCELTNDDGTMARAPECIEFANKHNMALVTIEDLVAYRQAHERKAS
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: SYS_BLOFL
Sequence: MLDTNLLFNHFEWVAKKLARKNFVLNFDELNQYNDLRKILQKKIEKLQIDRKNLSKTIILAKSQQINLQSLQKQARLLNQKLILIKSEIRTLKSKIKQYQLSIPNIPDDEIPNGFKDQDNIEIMRWGKVHKYDFKLLDHITLGKLIGGIDLSSASKITGTRFIILKGEIAYLHRALSQFMIDIHIQNHGYIEYYLPYLINVESLYGSGQLPKFYDDLFHTQSVVSVNSSKCSTYTLIPTAEVPLVNIMRSVTVHKNELPIKMVAHTPCFRLEAGTYGYRAHGLIRTHQFDKVELVQVVHPDQSVQALEEITNHAEKILQLLELPYRKMLLCAGNISFTSCKTYDLEVWLPARNEYCEISSCSNIRDFQSRRINARFKDGINKRSKLLHTLNASGVAVGRALVAILENYQLENGCIKIPEVLSPYMNGMTHIHYQNK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPHS1_ARATH
Sequence: MAEPEKKRDQPFSQEKDEEKDLYLVHDEHESPLPLTVTSRVLYMLGDIASGPAYRFTQWLDLVRKRSATYGSSGFPHRLHRIDDMVTSAGERNTDPKSPPSRQSSEISLWERLGKASTVDIDSSCFSWNMLSSLHHTEHSSSTDHSEEDQSKPLEVTVNSGGVVFFALFNSSSSEDASRKEEAAVIKFASSRMATQSERLGYEFSKWLGVQIPQARVIHSCNPEWTLIKEATEKAQAKATSEGDEVGEMTCSELLEALELSRCLLLMSYVHGCPMLESMSSFETEEKAERAAAALGRILVLDLVIRNEDRLPCRQLRWRGNPANLLLTDRIVSSAKHHECSFDEAFDSAIKRYHPKDYRSIQRERRASSVDSRSRLSISDQMLVSQASDFSDITESPRSYDTGLMSPMSDRSVAADFHLVAIDSGVPRRPPAGKRASDQEIYPRLVELLLNSSQYSSNLLHEITEGSLGYPQAEDGEETSNVRSVVTPVVREFRNGFRAGLRDLQEFHIFLVTLHQKLDVLLRAFFSMMDKTMCADFDREDFAVPESPSHTHGHEVNHYPSPSKDRVPSDNSSDHSESDMQKSVPRTPNSENKEDGSSPKSRESWHGRSGKGGESLSSQRLAAKLRDFHKFAKVDAESNKELDQWNETLRNEVMKLCQENGFNTGFFEGSDNNSCTDAYELKVRLEHILERISLISKAANTEKPSMIQENLFIGGGLAARSIYTLQHLGITHVLCLCANEIGQSDTQYPDLFEYQNFSITDDEDSNIESIFQEALDFIKHGEETGGKILVHCFEGRSRSATVVLAYLMLQKKLTLLEAWSKLRKVHRRAQPNDGFARILINLDKKCHGKVSMEWRQRKPTMKVCPVCGKNAGLSSSSLKLHLQKSHRKLSSGSVDSAMNMEIQKALEALKLSTGRGSSASSNSFQSHPG
What is the function of this protein?
Probable dual specificity phosphatase that binds and dephosphorylates MPK18, modulating the organization and dynamics of cortical microtubules.  Acts as negative regulator of abscisic acid (ABA) signaling during seed germination and light-induced stomata aperture.
What are the official names of this protein?
Dual specificity protein phosphatase PHS1, Protein PROPYZAMIDE-HYPERSENSITIVE 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUS5_ASHGO
Sequence: MNRWAVPILHEHKHYYIVNKVHGIVCQPPDLRTWYKYHDYEPPVLLDLLRKQHPNFGGEVWRTVHRLDEPVTGGVLVSRNKRAAAMFSRSLALGGNRGFPLTRRYVALLAREAKGLPSEGRITMGDMITDYKRLENDLVLLQLQTGRKHQIRKQMAQVFGQPVVNDKMYGGDSVDGIVDNLIGLHSAFIGAQCGLQARTYLIPIPRTQDAFKLWDKYIDEQGGFIPSVQKELRDFSLPSKLENTITLLSGGQGGIQISYK
What is the function of this protein?
Pseudouridylate synthase responsible for the pseudouridine-2819 formation in mitochondrial 21S rRNA.  May modulate the efficiency or the fidelity of the mitochondrial translation machinery.
What are the official names of this protein?
21S rRNA pseudouridine(2819) synthase, Pseudouridine synthase 5, Pseudouridylate synthase PUS5, Uracil hydrolyase PUS5.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RluA family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: LDHA_DISEL
Sequence: MSTKEKLISHVMKEEPVGSRNKVTVVGVGMVGMASAISILLKDLCDELAMVDVMEDKLKGEVMDLQHGSLFLKTKIVGDKDYSVTANSKVVVVTAGARQQEGESRLNLVQRNVNIFKFIIPNIVKYSPNCILMVVSNPVDILTYVAWKLSGFPRNRVIGSGTNLDSARFRHLIGEKLHLHPSSCHAWIVGEHGDSSVPVWSGVNVAGVSLQGLNPQMGTEGDGENWKAIHKEVVDGAYEVIKLKGYTSWAIGMSVADLVESIIKNMHKVHPVSTLVQGMHGVKDEVFLSVPSVLGNSGLTDVIHMTLKAEEEKQLQKSAETLWGVQKELTL
What is the function of this protein?
Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+).
What are the official names of this protein?
L-lactate dehydrogenase A chain, LDH-A.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTH_STRSV
Sequence: MTHVINLDGEHLTLEDVIAVARHGATCEIDQEAKKAVEASRKIVDDIVREKRVVYGVTTGFGSLCNVSISPEDTTQLQENLIRTHSSGYGDPLPEDAVRAIMLIRINSLVKGYSGIRLSTVEKLLELLNKGVVPYIPEKGSLGASGDLAPLAHMVLPMLGLGRAYYQGQLLSGQEALDKAGIEKIALAAKEGLALINGTTVLTGIGALATYDAIQLLKLSDVAGALSMEVHNGITSPFEEDLHTIRPQSGQLATARNIRNLLEGSGNTTVATQQRVQDPYTLRCIPQIHGASKDSIAYVKTKVEIEINSVTDNPIITKEGHVISGGNFHGEPMAQPFDFLGIAISEIGNVSERRVERLVNSQLSKLPSFLVKHPGLNSGFMITQYACASLASENKVLSHPASVDSIPSCENQEDFVSMGTTAARKAAEILKNSRRIVATEIMAACQALDLKPENHELGKGTKPAYDLFRQHVRFIEFDKDIEIYEELNKASELIENEEFLAAVEKAVDLSIQF
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VG030_BPPF1
Sequence: MLRYLSLFAVGLATGYAWGWIDGLAASLTV
What are the official names of this protein?
3.2 kDa protein, ORF 30.
Protein: SUFS_ECOLU
Sequence: MTFSVDKVRADFPVLSREVNGLPLAYLDSAASAQKPSQVIDAEAEFYRHGYAAVHRGIHTLSAQATEKMENVRKRASLFINARSAEELVFVRGTTEGINLVANSWGNSNVRAGDNIIISQMEHHANIVPWQMLCARVGAELRVIPLNPDGTLQLETLPTLFDEKTRLLAITHVSNVLGTENPLAEMITLAHQHGTKVLVDGAQAVMHHPVDVQALDCDFYVFSGHKLYGPTGIGILYVKEALLQEMPPWEGGGSMIATVSLSEGTTWTKAPWRFEAGTPNTGGIIGLGAALEYVSALGLNNIAEYEQNLMHYALSQLESVPDLTLYGPQNRLGVIAFNLGKHHAYDVGSFLDNYGIAVRTGHHCAMPLMAYYNVPAMCRASLAMYNTHEEVDRLVTGLQRIHRLLG
What is the function of this protein?
Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules.  Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation.  Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine.  Selenocysteine lyase activity is however unsure in vivo.
What are the official names of this protein?
Cysteine desulfurase, Selenocysteine beta-lyase, SCL, Selenocysteine lyase, Selenocysteine reductase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GALR2_MOUSE
Sequence: MNGSDSQGAEDSSQEGGGGWQPEAVLVPLFFALIFLVGAVGNALVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDDWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLALLFSGPYLSYYSQSQLANLTVCHPAWSAPRRRAMDLCTFVFSYLLPVLVLSLTYARTLHYLWRTVDPVAAGSGSQRAKRKVTRMIVIVAVLFCLCWMPHHALILCVWFGRFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRKICAGLLRRAPRRASGRVCILAPGNHSGGMLEPESTDLTQVSEAAGPLVPAPALPNCTTLSRTLDPAC
What is the function of this protein?
Receptor for the hormone galanin, GALP and spexin-1.  The activity of this receptor is mediated by G proteins that activate the phospholipase C/protein kinase C pathway (via G(q)) and that inhibit adenylyl cyclase (via G(i)).
What are the official names of this protein?
Galanin receptor type 2, GAL2-R, GALR-2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SPRE_CHLTE
Sequence: MKHILLITGAGKGIGRAIALEFARAARHHPDFEPVLVLSSRTAADLEKISLECRAEGALTDTITADISDMADVRRLTTHIVERYGHIDCLVNNAGVGRFGALSDLTEEDFDYTMNTNLKGTFFLTQALFALMERQHSGHIFFITSVAATKAFRHSSIYCMSKFGQRGLVETMRLYARKCNVRITDVQPGAVYTPMWGKVDDEMQALMMMPEDIAAPVVQAYLQPSRTVVEEIILRPTSGDIQDD
What is the function of this protein?
Catalyzes the final reductions in tetra-hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin.
What are the official names of this protein?
Sepiapterin reductase, SPR, cSR.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUCEN_RAT
Sequence: MRLLQVTALFFLLSNSLCRGENSKALTETSTTKASATTPDMVSITNKSTGGTPPKGTTNSATPKTPLMPALDSPTTPKHETTTRGVIKNEVSTIKTTVANPTISNAVSTLSSPQNKTENQSSIRTTEISGTNQLPDDQKPKTTETPSASLTTAKTISQIQDTEDGKITATTSTTPSYSSVILPVVIALIVITVLVFTLVGLYRICWKRDPGTPESGNDQPQSDKESVKLLTVKTISHESGEHSAQGKAKN
What is the function of this protein?
Endothelial sialomucin, also called endomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix.
What are the official names of this protein?
Endomucin.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: YQGF_BACAC
Sequence: MRILGLDVGTKTVGVAISDEMGWTAQGLETIKINEERGQFGFDRISELVKQYDVDKIVVGLPKNMNGTIGPRGEACQQFAENLRELLQLDVVMWDERLSTMAAERLLISADVSRKKRKQVIDKMAAVVILQGFLDSK
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPG_EHRRW
Sequence: MQCDFVDRILNEYDLLNAIVYRSKFTHEVKVGDVIIGGNNPIVVQSMALGGSGDVYQDAREVLELAQAGSELVRIAINSDKAIKSVPYIRDVLINHGFNSKMIIGCGQYEIARLVKQYPECALALGKIRINPGNIGFGDKRDKNFEDIIEFAIKNDIPIRIGVNWGSLDKYLAAKLMHDNSLRGTPDPDYVVLRKALVISAITSAKHAEKVGLPANKIVISCKVSKVRDLISVYTMLSKICDYPLHLGLTEAGSGVKGIVGSSAGISYLLLHGIGNTIRVSLTQQPGESRTNEVKLCQEILQSIGLRNFSVQVTSCPGCNRTNPKYFHQLVSDVNKYVADRMSVWKNANPGVENMTIAVMGCVVNGPGESKHANLGISMPGYGERSVAAVYQNGEKLCTLEGNNIFEQFVSIIENYVSIYYH
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: PTH_UREP2
Sequence: MEKYLIVGLGNPGSNYAKTRHNVGFMVINEICNKLNLSLDSSKFNGIFTKTIYNNSIVFFCQPTTYMNLSGEFVIKMLNFYNIPIKNLIVIYDDVDTKLGTIKLRKKGSSGGQNGIKNIINILKTDEIKRIRIGIDKDPHIKLDQYVLSNFKIDELVIIKPAIIKGALATLAAIGEDFDKVMNKFN
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1081_THEMA
Sequence: MFPYKIVDDVVILMPNKELNIENAHLFKKWVFDEFLNKGYNKIFLVLSDVESIDSFSLGVIVNILKSISSSGGFFALVSPNEKVERVLSLTNLDRIVKIYDTISEAMEEVRRK
What is the function of this protein?
In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts an anti-sigma factor and thus releases a sigma factor from inhibition.
What are the official names of this protein?
Putative anti-sigma factor antagonist TM_1081.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-factor antagonist family.
Protein: PIP12_MUSAM
Sequence: MEGKEEDVRLGANKFTERQPIGTAAQSQDKDYKEPPPAPLFEPGELSSWSFYRAGIAEFVATFLFLYITILTVMGVVKSSTKCSTVGIQGIAWAFGGMIFALVYCTAGISGGHINPAVTFGLFLARKLSLTRALFYMVMQCLGAICGAGVVKGFQKGLYENNGGGANVVAPGYTKGDGLGAEIVGTFILVYTVFSATDAKRSARDSHVPILAPLPIGFAVFLVHLATIPITGTGINPARSLGAAIIYNKGHAWDDHWIFWVGPFIGAALAALYHQVVIRAIPFKSRS
What is the function of this protein?
Water channel required to facilitate the transport of water across cell membrane; mercury-insensitive (By similarity).  Contributes to the tolerance to multiple abiotic stresses including salt (NaCl), cold and water deprivation, by modulating cytosolic K(+)/Na(+) ratio, maintaining osmotic balance, and reducing membrane injury (e. g.  oxidative injury) (By similarity).
What are the official names of this protein?
Aquaporin PIP1-2, Plasma membrane intrinsic protein 1-2, MusaPIP1-2, MusaPIP1;2.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family. PIP (TC 1.A.8.11) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NCTR1_MOUSE
Sequence: MLPTLTALLCLGLCLSQRINTEKETLPKPIIWAKPSIMVTNGNSVNIWCQGAQSASEYQLYFEGSFFALERPKPSRSMNKVRFFISQMTSHTAGIYTCFYQSGELWSKSSNPLKLVVTGLYDTPNLWVYPRPEVTLGENVTFFCQLKTATSKFFLLKERGSNHIQNKYGNIQAEFPMGPVTRAHRGTYRCFGSYNDYAWSFPSEPVTLLITGGVENSSLAPTDPTSSLDYWEFDLSTNESGLQKDSAFWDHTTQNLIRIGLACIILITLVWLLTEDWLSKRKDHEEANRLTNWECRRRWRMQHYFEEEQRNAISMMELKATPGAL
What is the function of this protein?
Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
What are the official names of this protein?
Natural cytotoxicity triggering receptor 1, Activating receptor 1, mAR-1, Lymphocyte antigen 94, Natural killer cell p46-related protein, NK-p46, NKp46, mNKp46.
What is the protein family that this protein belongs to?
Belongs to the natural cytotoxicity receptor (NCR) family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: NORV_SHISS
Sequence: MSIVVKNNIHWVGQRDWEVRDFHGTEYKTLRGSSYNSYLIREEKNVLIDTVDHKFSREFVQNLRNEIDLADIDYIVINHAEEDHAGALTELMAQIPDTPIYCTANAIDSINGHHHHPEWNFNVVKTGDTLDIGNGKQLIFVETPMLHWPDSMMTYLTGDAVLFSNDAFGQHYCDEHLFNDEVDQTELFEQCQRYYANILTPFSRLVTPKITEILGFNLPVDMIATSHGVVWRDNPTQIVELYLKWAADYQEDRITIFYDTMSNNTRMMADAIAQGIAETDPRVAVKIFNVARSDKNEILTNVFRSKGVLVGTSTMNNVMMPKIAGLVEEMTGLRFRNKRASAFGSHGWSGGAVDRLSTRLQDAGFEMSLSLKAKWRPDQDALELCREHGREIARQWALAPLPQSTVNTVVKEETSATTKSDLGPRMQCSVCQWIYDPAKGEPMQDVAPGTPWSEVPDNFLCPECSLGKDVFDELASEAK
What is the function of this protein?
Anaerobic nitric oxide reductase; uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes.  Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified.  NO probably binds to the di-iron center; electrons enter from the NorW at rubredoxin and are transferred sequentially to the FMN center and the di-iron center.  Also able to function as an aerobic oxygen reductase.
What are the official names of this protein?
Anaerobic nitric oxide reductase flavorubredoxin, FlRd, FlavoRb.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2590_BRUA1
Sequence: MTADVPNARLVDVELDESIGRSTPDVEHERAVAIFDLIEENSFHPVGDQKGGPYRLKLSLMESRLIFSITRENGDAVATHILSLTPLRRVVRDYFMICESYYQAIRSATPSKIEAIDMGRRGLHNEGSQTLQARLKGKIEVDFDTARRLFTLVCVLHWRG
What are the official names of this protein?
UPF0262 protein BAbS19_I02590.
What is the protein family that this protein belongs to?
Belongs to the UPF0262 family.
Protein: TYDP2_XENTR
Sequence: MEKEDAGAVQCGTGEGEAVVLNERSEQCSAFASIAGCDEAVAQCFLAENDWDMERAINSFFEPGVESALQNKAAADIADPLKQETMSGTASDSCIDLTGDDLVVTKSEATTSNSSTVKQEDESHFSFLTWNIDGLDESNVAERARGVCSYLALYSPDVVFLQEVIPPYYEYLKKRAVSYTIITGNEDEYFTAMMLKKSRVKLISQEIVPYPSTVMMRNLLVANVNISGNSICLMTSHLESTKDHSKERLKQLDIVLKKMMDAPPLATVIFGGDTNLRDQEVAKIGGMPNNILDVWDFLGKPEHCRYTWDTKVNKNLRAPYICRLRFDRIFFRASQEGSQVIPQSLYLAGTEKLDCGRFPSDHWGLLCDFAIIL
What is the function of this protein?
DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate.  Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (top2) active site tyrosine residue.  Hydrolyzes 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals.
What are the official names of this protein?
Tyrosyl-DNA phosphodiesterase 2, Tyr-DNA phosphodiesterase 2, 5'-tyrosyl-DNA phosphodiesterase, 5'-Tyr-DNA phosphodiesterase, TRAF and TNF receptor-associated protein homolog.
What is the protein family that this protein belongs to?
Belongs to the CCR4/nocturin family. TTRAP/TDP2 subfamily.
What are the subcellular locations of this protein?
Nucleus. Nucleus, PML body.
Protein: Y2343_ARCFU
Sequence: MNEALLREIYSEVKKIREKIEQLEELIIPAEKVSEEELLEIRKLKEESLKGEHVDWDELKRELGV
What are the official names of this protein?
Uncharacterized protein AF_2343.
Protein: RL36_HELPS
Sequence: MKVRPSVKKMCDKCKIIKRRGVIRVICATPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: RAD25_YEAST
Sequence: MTDVEGYQPKSKGKIFPDMGESFFSSDEDSPATDAEIDENYDDNRETSEGRGERDTGAMVTGLKKPRKKTKSSRHTAADSSMNQMDAKDKALLQDTNSDIPADFVPDSVSGMFRSHDFSYLRLRPDHASRPLWISPSDGRIILESFSPLAEQAQDFLVTIAEPISRPSHIHEYKITAYSLYAAVSVGLETDDIISVLDRLSKVPVAESIINFIKGATISYGKVKLVIKHNRYFVETTQADILQMLLNDSVIGPLRIDSDHQVQPPEDVLQQQLQQTAGKPATNVNPNDVEAVFSAVIGGDNEREEEDDDIDAVHSFEIANESVEVVKKRCQEIDYPVLEEYDFRNDHRNPDLDIDLKPSTQIRPYQEKSLSKMFGNGRARSGIIVLPCGAGKTLVGITAACTIKKSVIVLCTSSVSVMQWRQQFLQWCTLQPENCAVFTSDNKEMFQTESGLVVSTYSMVANTRNRSHDSQKVMDFLTGREWGFIILDEVHVVPAAMFRRVVSTIAAHAKLGLTATLVREDDKIGDLNFLIGPKLYEANWMELSQKGHIANVQCAEVWCPMTAEFYQEYLRETARKRMLLYIMNPTKFQACQFLIQYHERRGDKIIVFSDNVYALQEYALKMGKPFIYGSTPQQERMNILQNFQYNDQINTIFLSKVGDTSIDLPEATCLIQISSHYGSRRQEAQRLGRILRAKRRNDEGFNAFFYSLVSKDTQEMYYSTKRQAFLVDQGYAFKVITHLHGMENIPNLAYASPRERRELLQEVLLKNEEAAGIEVGDDADNSVGRGSNGHKRFKSKAVRGEGSLSGLAGGEDMAYMEYSTNKNKELKEHHPLIRKMYYKNLKK
What is the function of this protein?
ATP-dependent 3'-5' DNA helicase, component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II.  In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment.  The ATPase activity of XPB/SSL2, but not its helicase activity, is required for DNA opening.  In transcription, TFIIH has an essential role in transcription initiation.  When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.  The ATP-dependent helicase activity of XPB/SSL2 is required for promoter opening and promoter escape.  Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription (PubMed:8269516, PubMed:7693549, PubMed:7961739, PubMed:8202161, PubMed:7813015, PubMed:8631896).  XPB/SSL2 acts as a double-stranded DNA translocase promoting DNA opening by tracking along the nontemplate promoter strand, rotating and inserting DNA into the Pol II active site cleft, leading to DNA unwinding.  May also use this translocase mechanism during DNA repair rather than physically wedging open damaged DNA (PubMed:25775526).
What are the official names of this protein?
General transcription and DNA repair factor IIH helicase subunit XPB, TFIIH subunit XPB, DNA repair helicase RAD25, RNA polymerase II transcription factor B subunit SSL2, TFB subunit SSL2, Suppressor of stem-loop mutation 2.
What is the protein family that this protein belongs to?
Belongs to the helicase family. RAD25/XPB subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: GST28_SCHHA
Sequence: MTGDHIKVIYFNGRGRAESIRMTLVAAGVNYEDERISFQDWPKIKPTIPGGRLPAVKITDNHGHVKWMLESLAIARYMAKKHHMMGETDEEYYNVEKLIGQVEDLEHEYHKTLMKPEEEKQKITKEILNGKVPVLLDIICESLKASTGKLAVGDKVTLADLVLIAVIDHVTDLDKEFLTGKYPEIHKHRENLLASSPRLAKYLSDRAATPF
What is the function of this protein?
GST isoenzymes appear to play a central role in the parasite detoxification system.  Other functions are also suspected including a role in increasing the solubility of haematin in the parasite gut.
What are the official names of this protein?
Glutathione S-transferase class-mu 28 kDa isozyme, GST 28, Sh28GST.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Mu family.
Protein: CA12_CONPE
Sequence: MFTVFLLVVLATTVVSFTSDRASDGGNAAMSDLIALTIKGCCSHPPCFLNNPDYCG
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.  This toxin inhibits human alpha-7/CHRNA7 and alpha-9-alpha-10/CHRNA9/CHRNA10 AChR (complete inhibition at 3 uM of toxin).  In addition, this toxin inhibits high voltage-activated (HVA) calcium channel currents in rat DRG neurons (22% inhibition at 1 uM toxin) probably by activating GABA(B) receptors (GABBR1 and/or GABBR2) (PubMed:26948522).
What are the official names of this protein?
Alpha-conotoxin Pn1.2.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CA13_CONLT
Sequence: MGMRMMFTMFLLVVLTTTVVSFNLDRESNHENRRTSNQITRGMWDECCDDPPCRQNNMEHCPAS
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them (By similarity).  Has possibly a distinct nAChR binding mode from other alpha-conotoxins, due to a different three residue motif (lacks the Ser-Xaa-Pro motif) (By similarity).
What are the official names of this protein?
Alpha-conotoxin-like Lt1.3, Lt1c.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.