PharMolix/UniProtQA huggingface dataset:
Protein: LRC8B_MOUSE
Sequence: MITLTELKCLADAQSSYHILKPWWDVFWYYITLIMLLVAVLAGALQLTQSRVLCCLPCKVEFDNQCAVPWDLLKGSENASSNSGLLLPLPLRIQNDLHRQQYSYIDAVCYEKQLHWFAKFFPYLVLLHTLIFAACSNFWLHYPSTSSRLEHFVSILHKCFDSPWTTRALSETVAEQSVRPLKLSKSKTLLSTSGGSADIDASKQSLPYPQPGLESPGIESPTSSVLDKKEGEQAKAIFEKVKRFRLHVEQRDIIYRVYLKQIIVKVILFVLIITYVPYFLSYITLEIDCSIDVQAFTGYKRYQCVYSLAEIFKVLASFYVILVMLYGLTSSYSLWWMLRSSLKQYSFEALREKSNYSDIPDVKNDFAFILHLADQYDPLYSKRFSIFLSEVSENKLKQINLNNEWTVERLKSKLVKNSQDKVELHLFMLNGLPDNVFELTEMEVLSLELIPEVKLPAAVAQLVNLRELHVYHSSLVVDHPALAFLEENLRILRLKFTEMGKIPRWVFHLKNLKELYLSGCVLPEQLSSLHLEGFQDLKNLRTLYLKSSLSRIPQVVTDLLPSLQKLSLDNEGSKLVVLNNLKKMVNLKSLELLSCDLERIPHSIFSLNNLHELDLKENNLKTVEEIISFQHLPSLSCLKLWHNNIAYIPAQIGALSNLEQLFLGHNNIESLPLQLFLCTKLHYLDLSYNHLTFIPEEIQYLTNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGRNSLTDLSPLVGELSNLTHLELTGNYLETLPVELEGCQSLKRSCLIVEDSLLNSLPLPVAERLQTCLDKC
What is the function of this protein?
Non-essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes.  The VRAC channel conducts iodide better than chloride and can also conduct organic osmolytes like taurine.  Channel activity requires LRRC8A plus at least one other family member (LRRC8B, LRRC8C, LRRC8D or LRRC8E); channel characteristics depend on the precise subunit composition.
What are the official names of this protein?
Volume-regulated anion channel subunit LRRC8B, Leucine-rich repeat-containing protein 8B.
What is the protein family that this protein belongs to?
Belongs to the LRRC8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane. Note=In the absence of LRRC8A, resides primarily in a cytoplasmic compartment, probably the endoplasmic reticulum. Requires LRRC8A for expression at the cell membrane.
Protein: RF3_SYNE7
Sequence: MGVHSFLCSSPWFRMVTDLQKEIQEAVQQRRNFAIISHPDAGKTTLTEKLLLYGGAIQEAGAVKAKRSQRAATSDWMELEKQRGISITSTVLQFNYHDCTINLLDTPGHQDFSEDTYRTLAAADNAVMLEDAAKGLEPQTRKLFEVCRMRNIPIFTFFNKMDRPGREPLELLDEIEQELGLQTYAVNWPIGSGDRFRGVFDRRKQQVHLFERSVHGKRQAKDTTLEWGDPQLADLIEPDLLQQLQDELELLEGVGTEFDLEAIHAGQLTPVFWGSAMTNFGVELFLEAFLDYALKPGARRSSVGDMAPDYPEFSGFVFKLQANMDPRHRDRIAFVRVCTGKFEKDMTVQHARSGRTLRLSRPQKLFGQDREVLDDAYPGDVIGLNNPGMFAIGDTIYTGKRLEYDGIPCFSPEIFAYLRNPNPSKFKPFRKGVSELREEGAVQIMYSADSAKRDPILAAVGQLQLEVVQYRLENEYGVETLLEPLPFSVARWVEGGWDVLEKVGRLFNTTTVKDTWGRPVLLFKNEWNLRQIEADHPELQLRSVAPVAAGQEPIEV
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTOX_ECOBW
Sequence: MKYDLIIIGSGSVGAAAGYYATRAGLNVLMTDAHMPPHQHGSHHGDTRLIRHAYGEGEKYVPLVLRAQTLWDELSRHNEEDPIFVRSGVINLGPADSTFLANVAHSAEQWQLNVEKLDAQGIMARWPEIRVPDNYIGLFETDSGFLRSELAIKTWIQLAKEAGCAQLFNCPVTAIRHDDDGVTIETADGEYQAKKAIVCAGTWVKDLLPELPVQPVRKVFAWYQADGRYSVKNKFPAFTGELPNGDQYYGFPAENDALKIGKHNGGQVIHSADERVPFAEVASDGSEAFPFLRNVLPGIGCCLYGAACTYDNSPDEDFIIDTLPGHDNTLLITGLSGHGFKFASVLGEIAADFAQDKKSDFDLTPFRLSRFQ
What is the function of this protein?
Catalyzes the oxidative demethylation of N-methyl-L-tryptophan.
What are the official names of this protein?
N-methyl-L-tryptophan oxidase, MTOX.
What is the protein family that this protein belongs to?
Belongs to the MSOX/MTOX family. MTOX subfamily.
Protein: PUM13_ARATH
Sequence: MDNKFYVNTNGERNIWSTAAEENMTTAASSSQSQPPQMQSSKFHQPENHIHINDGFSSGAFDLQTLESSFRGLSFADSNVHQNGNPILPAHQYNQVFNGGGGSYGDGYLFPPSGSYHHYELKDLQRFNQNQQRLSYQNDYVNQSYRYDTIGGGNGMLNNSFLNGVPCASRNNVSDYYTNIFGYGVNNSWRSNEGCTYNQDQAASSMENGRGSYFSIATDRVWSKELEKTIFVGTKETIDMIFDGLIVGICELMVDPFGNDVVKLLIGKCSSEQIILIVDVVTRHISKFVNICFNPIGTLAIQVLLTSIHERANNQIPRIMDAISSVALQLTRNTNAKYVILACFRMFTSSQCRRLLEVVSQHCYQIAIDQNGCCLLQQCFDKERVPNHEIRQRLISEVIEHALKLCLNCHGNYVVQYVVELDNQHETDLLVNKLLRNYAHLARNKYGSHVVQKLLKLRGIDSKLIVVDLLRGIDTLLLDPFGNYVIQTAWFVSKEDVRQMLRYYIERNIRLMRCNKFGNKILEKLNI
What is the function of this protein?
Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs.
What are the official names of this protein?
Putative pumilio homolog 13, APUM-13, AtPUM13.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMS_GEOSL
Sequence: MCGIVGYIGAQEATPIILDGLKRLEYRGYDSAGICTLLEGKADKRRSEGKLINLERLIQSTPLAGRIGIGHTRWATHGPPSERNAHPHQAGSIIVVHNGIIENYLELKQRLVTSGRVFNSDTDTEVIAHLIDDKFAGTGDFERAVREALAEVRGAYALCILCEREPGVLIAAKQGSPMVVGLGEGEFFVASDIPAILSHTREMVFMEDGEIVVFRDGHPTFSTVAGAPLDKKSRHIDWSPLMAEKGGYKHFMLKEIFEQPRAVQDTITGRLLEEQGDVRLEEMKLADEQLRGIGRICIVACGTSWHSALVGKFLMEEHCRIPVEVDIASEFRYRNPVIDSKTLLLVISQSGETADTLAALREAKARGAMTAAICNVVDSSIAREAHGVLYTHAGPEIGVASTKAFVTQLVALYLFTIRLGRAVGTIDCEQGRTMIGGLLKVPALLEQALETNEQVERIARRYMNARDFLYLGRGMNYPIALEGALKLKEISYIHAEGYPAGEMKHGPIALIDENMPVVVLVPKNSTYEKVLSNMEEVIARGGRVIAICSAGDEAIAKKAEVTLEVPTDGEELAPIILSVPLQLLAYHVAVLKGTDVDQPRNLAKSVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S36A3_MOUSE
Sequence: MGNVPLLREVGKCQRNMFGRSTASSKGSSNSRSSSSTSPKKGPRREADALMFIQIFIHLLKSNIGTGFLGLPLAVKNAGLLVGPVSLLAIGALTVHCMDILLNCACHLTQRLQRSFVNYEETTMYSLETCPSPWLRTHSVWGRYVVSFLLIVTQLGFCSVYFMFLADNLQQIMEEAHFTSNVCQPRQSLVMTSILDTRFYMLTILPFLILLVLIQNPQVLSIFSTLATITTLSSLALIFEYLIQTPHHSNLPLVANWKTFLLFFGTAIFTFEGVGMVLPLKSQMKSPQQFPAVLYLGMSFVIFLYICLGTLGYMKFGTDTQASITLNLPICWLYQSVKLMYSVGIFFTYALQFHVPAEIIVPYVVSRVSENWALFVDLTVRTALVCLTCFSAVLIPRLDLVISLVGSVSSSALAIIIPPLLEIATFYSENISCATIVKDIMISILGLLGCVLGTYQALYEMTQQTHFYMANSTRVHI
What are the official names of this protein?
Proton-coupled amino acid transporter 3, Proton/amino acid transporter 3, Solute carrier family 36 member 3, Tramdorin-2.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CITX_ECOBW
Sequence: MHLLPELASHHAVSIPELLVSRDERQARQHVWLKRHPVPLVSFTVVAPGPIKDSEVTRRIFNHGVTALRALAAKQGWQIQEQAALVSASGPEGMLSIAAPARDLKLATIELEHSHPLGRLWDIDVLTPEGEILSRRDYSLPPRRCLLCEQSAAVCARGKTHQLTDLLNRMEALLNDVDACNVN
What is the function of this protein?
Transfers 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A on a serine residue to the apo-acyl carrier protein (gamma chain) of the citrate lyase to yield holo-acyl carrier protein.
What are the official names of this protein?
Probable apo-citrate lyase phosphoribosyl-dephospho-CoA transferase, Apo-ACP nucleodityltransferase, Holo-ACP synthase, Holo-citrate lyase synthase.
What is the protein family that this protein belongs to?
Belongs to the CitX family.
Protein: NRFA_PORGI
Sequence: MKNKERKLKSWQGWLIFSSSMVVVFCLGLLAASVTERRAEIQSIYANKKDKIAPFEARNEMYRGNYPREYETWTYTADTSFRSEFNGSQAIDVLEQRPNMVIFWAGYAFSRDYTSPRGHMHAIQDMQRTLRTGNPGIDGAGDMQPATCWVCKSPDVPRMMQAIGVDEFYKNKWSSLGSDIVNPIGCADCHDPETMDLHISRPALIEAFQRRGLDITKASHQEMRSLVCAQCHVEYYFKGEGKYLTFPWDKGMTMEDAERYYDEAEYYDYIHTLSRAPILKAQHPDFEISQHGIHAQRGVSCADCHMPYISEGGVKFSDHHITSPLAHMDRTCQTCHRESEEELRKNVYERQRKANEVRNQLENELAKAHLEAQFAWDKGATEKEMTPILKYIRQSQWRWDYGVASHGASFHAPQEITRILSNGLERAMQARIEIARVLARHGYTDEVPLPDVSTKEKAQKYIGLDMDGLHKNKEKFLETVVPKWVKKAKGKGLLIAAK
What is the function of this protein?
Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process.
What are the official names of this protein?
Cytochrome c-552, Ammonia-forming cytochrome c nitrite reductase, Cytochrome c nitrite reductase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c-552 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: FIB11_BPE32
Sequence: MARELMPKSGIMMPHVVVTRDAAVVGVSTVDGQAGAIDLTGKYLQKTDAAATYQTKTEGASKDFVLDSIQPIMSGALFREDPWVVNDTPFRSTGANGVESVDMMKVTPDNSIKIGSYASSVQGVEIHSAGRLQVVDQNDSGVETKYPVYSKRYRPEIEDLPFAAIGSYVKDSKGRTIGVNRTGINSDIKQLTQKVTFTQPVTVPDAVGDYDAVTLRQLRNSGGGSGGPTMSGISNFGIGDFHLRDSRAFIPAFEVVSDGQLLNRADYPDLWAYAQLLSPIEDSEWVSNVYQRGKYSKGNGTTTFRVPDRNGVQSGSIQGLFGRGDAGSSGSNGVVSDSGAPNITYSSPHTMVTLASASGQVATNGAIQSITSTDDVAPVGTGGKYISTNFDASRSSAVYGRSLSEVVPRNFIGVWTIRAHGGFTAANTSWSVINSDASEQPTGTPITGGLVSSKYVVGGVDKYRSSIQLLGSNEVDLSTRITTINDRYAIGAATWDFKLDGKLLFNKSLTPKGTGESPGNTYLTLANTWMSAAYSGYIGFVGGGVGVSNGGWRNFISLGSLIFPDSSHPTAVISQVYDYDLSTGSQPNGDIVRNTYFSAESYDITFGNNSGTTNYIFSKSPVSDERLKHSIKEEGTATALSNLNKMEYKTFIYNYDEKATVRRGFIAQQLEAIDPQYVRKYKTFKGTDTLALDENVLLLDAIAAIQELTKKVEVLEAKLAEK
What is the function of this protein?
Probable tail fiber protein.
What are the official names of this protein?
Probable tail fiber protein, Gene product 11, gp11.
What are the subcellular locations of this protein?
Virion.
Protein: DGOT_ECOLI
Sequence: MDIPVNAAKPGRRRYLTLVMIFITVVICYVDRANLAVASAHIQEEFGITKAEMGYVFSAFAWLYTLCQIPGGWFLDRVGSRVTYFIAIFGWSVATLFQGFATGLMSLIGLRAITGIFEAPAFPTNNRMVTSWFPEHERASAVGFYTSGQFVGLAFLTPLLIWIQEMLSWHWVFIVTGGIGIIWSLIWFKVYQPPRLTKGISKAELDYIRDGGGLVDGDAPVKKEARQPLTAKDWKLVFHRKLIGVYLGQFAVASTLWFFLTWFPNYLTQEKGITALKAGFMTTVPFLAAFVGVLLSGWVADLLVRKGFSLGFARKTPIICGLLISTCIMGANYTNDPMMIMCLMALAFFGNGFASITWSLVSSLAPMRLIGLTGGVFNFAGGLGGITVPLVVGYLAQGYGFAPALVYISAVALIGALSYILLVGDVKRVG
What is the function of this protein?
Involved in D-galactonate metabolism (PubMed:211976, PubMed:30455279).  Catalyzes the proton-dependent uptake of galactonate into the cell (PubMed:31083648).
What are the official names of this protein?
D-galactonate transporter, D-galactonate/H(+) symporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Phthalate permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL18_THEP1
Sequence: MIKKESKKEQRLRRHRRVRKKVFGTPERPRLCVFRSNKHIYAQIIDDTIGHTLVSASTLDPELREKLQKTWNVEAAKEVGLLIGKRALEKGIKKVVFDRGGYKYHGRVKALADGAREAGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: Y1380_XANP2
Sequence: MTLPAFLFAALGEIAGCFAVWHVVRLGGSHWWLLPGIVSLAAFAYALTFVEAEAAGRAFAAYGGIYILSSLVWMWTVEGVRPDRWDATGAALCLAGAAVIVFGPRG
What are the official names of this protein?
UPF0060 membrane protein Xaut_1380.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DXR_BUCA5
Sequence: MKKITILGSTGSIGINALSIIQKNPDLFKVIALVANKNFSIMLRQCELFSPDWVAMRDEKSAHILRKKLKHSKINTQVLTGEKDICALAALEETDHVISAIVGMAGLLPTLSAIHAGKTILLANKESLITSGYFFMKALSSSGAKIIPIDSEHNAIFQVLPLEIQKNLGKTTLEKNSIKHLVLTGSGGPFYKFSSSDLSNVTPDQACSHPNWLMGKKISVDSATMMNKGLEYAEARWLFNALESEIKILIHPESIIHSMVQYYDGSLLAQLSAPDIRTSISYAMSWPDRICTEVDYLNFYKINNLTFFEPDFTQFPCLKLAIDAFSQGQASMTVLNAANEIAVSSFLDSKISFTKIYEINMEILMSSCFSEPKCIQDILEIDRKVRILAKNKVSSLIF
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: ATPE_ECO45
Sequence: MAMTYHLDVVSAEQQMFSGLVEKIQVTGSEGELGIYPGHAPLLTAIKPGMIRIVKQHGHEEFIYLSGGILEVQPGNVTVLADTAIRGQDLDEARAMEAKRKAEEHISSSHGDVDYAQASAELAKAIAQLRVIELTKKAM
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y1461_MYCTU
Sequence: MTLTPEASKSVAQPPTQAPLTQEEAIASLGRYGYGWADSDVAGANAQRGLSEAVVRDISAKKNEPDWMLQSRLKALRIFDRKPIPKWGSNLDGIDFDNIKYFVRSTEKQAASWDDLPEDIRNTYDRLGIPEAEKQRLVAGVAAQYESEVVYHQIREDLEAQGVIFLDTDTGLREHPDIFKEYFGTVIPAGDNKFSALNTAVWSGGSFIYVPPGVHVDIPLQAYFRINTENMGQFERTLIIADEGSYVHYVEGCLPAGELITTADGDLRPIESIRVGDFVTGHDGRPHRVTAVQVRDLDGELFTFTPMSPANAFSVTAEHPLLAIPRDEVRVMRKERNGWKAEVNSTKLRSAEPRWIAAKDVAEGDFLIYPKPKPIPHRTVLPLEFARLAGYYLAEGHACLTNGCESLIFSFHSDEFEYVEDVRQACKSLYEKSGSVLIEEHKHSARVTVYTKAGYAAMRDNVGIGSSNKKLSDLLMRQDETFLRELVDAYVNGDGNVTRRNGAVWKRVHTTSRLWAFQLQSILARLGHYATVELRRPGGPGVIMGRNVVRKDIYQVQWTEGGRGPKQARDCGDYFAVPIKKRAVREAHEPVYNLDVENPDSYLAYGFAVHNCTAPIYKSDSLHSAVVEIIVKPHARVRYTTIQNWSNNVYNLVTKRARAEAGATMEWIDGNIGSKVTMKYPAVWMTGEHAKGEVLSVAFAGEDQHQDTGAKMLHLAPNTSSNIVSKSVARGGGRTSYRGLVQVNKGAHGSRSSVKCDALLVDTVSRSDTYPYVDIREDDVTMGHEATVSKVSENQLFYLMSRGLTEDEAMAMVVRGFVEPIAKELPMEYALELNRLIELQMEGAVG
What are the official names of this protein?
UPF0051 protein Rv1461.
What is the protein family that this protein belongs to?
Belongs to the UPF0051 (ycf24) family.
Protein: LEPA_STREM
Sequence: MNSQELKKRQENIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYKAKNGQDYIFHLIDTPGHVDFTYEVSRSLAACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVIGLDASEAVLASAKSGIGIEAILEQIVEKVPAPSGDVDKPLQALIFDSVYDAYRGVILQVRVVNGMVKPGDTIQMMSNGKTFDVTEVGIFTPKAIGRDFLATGDVGYIAASIKTVADTRVGDTVTLATNPAAEPLHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNTTDGDMLEVSNPSEFPDPTKVDSIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVNVIYHIPLAEIVFDFFDKLKSSTRGYASFDYEIAEYRRSQLVKMDILLNGDKVDALSFIVHREFAYERGKLIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDESKK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DHS3_CAEEL
Sequence: MPYVFLLSPQLEIASQWDGYYEKTFEVSDHVHKEIILKVSGQTVLITGSGSGLGRLMAFEFGKLGARLVLWDINEQGNKETLKELEAMGVEAKAYTVDLSEYKEINRTADLVKSEVGKVDILVNNAGIVTGKKLLQCPDELMVKTVSVNTNALFFTTKNFLPGMLESNKGHIVTIASMAGKCGVAGLVDYCASKHGAVGFNDSLASELYALKKDVKTTVVCPIYINTGMFDGIATKWPTLLPILSPEYVVDCIMEAVLTDRAFLAIPKFSYIFIALAGLLPTEVLNLYGDHFGITHSMDHFKGRQSRQA
What is the function of this protein?
May play a role in lipid droplet formation.  May modulate triglyceride levels.
What are the official names of this protein?
Protein dhs-3, Alcohol dehydrogenase dhs-3.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Lipid droplet.
Protein: HEMH_PSEMY
Sequence: MTDHALLLANLGSPASTEVADVRRYLNQFLMDPYVIDLPWPLRRLLVSLILIKRPAASAHAYASIWWDEGSPLVVLSRRLQEAMKTHWSHGPVELAMRYGEPSIEATLQRLADQGVRQVTLAPLYPQFADSTTTTVIEEAKRVVRQRSLDLRFSVLPPFYDQPEYLDALVASAKPYLEQGFDHLLLSFHGLPERHLHKLDPSGHCLKGDDCCRTASPAVLATCYRAQCLRSAELFAERMGLRPEQWSVSFQSRLGRAKWIEPYTETRLDELAAQGVKKLLVMCPAFVADCIETLEEIGDRGREQFVEAGGESLQLVPCLNDHPDWVAALKVLCERAPQAL
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAP2_AJECH
Sequence: MGSKTPGNHRRDPNESSRPPAIDAINPPKQAAASGLVHGSLEGESQKRNKRKKKKKKKNTKELEILQTTPPRVALANIFRSQRYPEAEIVKYSSDNDNLQRTTAEELRHLSVLNAMDDEFLNDYRNAAEVHRQVRQYVQTIIKPGIALSQLAQEIEDGVRALTNHQGLETGDALKAGMAFPTGLCLNNIAAHWTPNPGAKEVILQYDDVLKIDFGVHVNGRIVDSAFTMAFNPVYDNLLAAVKNATNTGLKEAGIDARIAHISETIQEVMESYEVELNRKVIPVKAVRNITGHNILHYKIHGDKQVPFVKTQTNQRMEEGDVFAIETFGSTGKAYLDDATGIYGYGYDENASTAGLHHSSAKSLLKTIKENFGTLVFSRRYLERLGVQRYHLGMRSLVTNGIVQSYAPLVDVPGSYVAQFEHTVLLRPNCKEVISRGDDY
What is the function of this protein?
Cotranslationally removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
What are the official names of this protein?
Methionine aminopeptidase 2, MAP 2, MetAP 2, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_BACC1
Sequence: MARVCAITGRKARSGNSRSHAMNATKRKWGANLQKVRVRIDGKVQRVYVSARALKSGKIERV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: MFS4B_HUMAN
Sequence: MLCASFLGLGLSVAIVGPTFQDLATNVNRNISSLSFIFVGRALGYLSGSVIGGFLVDVMNYFLLLGISMSATTVGLYLVPFCKTAILLTVMMSIFGVSIGILDTGGNVLILAIWGDKGAPHMQALHFSFALGAFLAPLLAKLALGPTASAENHTESDFHPALNQSSDADSEALFGVPNDKNLLWAYAVIGTYMFLVSVIFFCLFLKNSSKQEKARASAETFRRAKYHNALLCLLFLFFFFYVGAEVTYGSYVFSFATTHAGMKESEAAGLNSIFWGTFAACRGLAIFFATCLQPGTMIVLSNIGSLTSSLFLVLFDKNPICLWIATSVYGASMATTFPSGVSWIEQYTTIHGKSAAFFVIGASLGEMAIPAVIGILQGKYPDLPVVLYTSLGASIATGILFPVLYKLATSPLDRQRKEDRKSEDQKALLSSSGLNEYEEENEEEDAEKWNEMDFEMIETNDTMRHSIIETSRSSLTEPTAEVYNQYPSNALVFESSPFNTGSAHVKHLPETRTKGTNV
What is the function of this protein?
May function as a sodium-dependent glucose transporter.  Potential channels for urea in the inner medulla of kidney.
What are the official names of this protein?
Sodium-dependent glucose transporter 1, Major facilitator superfamily domain-containing protein 4B.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
Protein: ASP1_TOXGO
Sequence: MSPSSRFRNLVSVDSSSQDFGKRSSLYASLLDSASVSSLPGICSTAEDRDVEDESWKDPSSSSHCAKTEGGACAFPRLNQVLSSLRDPMGVFSRAKRRRSLGKAVGLSTSVICVVALFGIVCLCLYGLVNFSFTSVETSPLDDPRNSPVMGELGNPQASTPSSARADTPARHDRQNQMFSPWSVQNEQFLGEDSDALPHAGPLFRSGVMVMPLRKMKSLRRIGWDKNTITVPDLQAHLVAALRMQEGLSKKDDGNLSGLSDGDDISIHDYMNSQYYTEIYVGSPGQKVRVVVDTGSSDLWVCSASCGILLNILHKTYNHGKSDTYHADGTPYHVQYASGPVGGFLSADDVALASLKTKNFLLAEAVDLKGLGTAFFFGKFDGILGMGFPSLATKGLKPFMQAAVEQNVVKNWVFVFYLASANGVDGELAIGGVDQERFIGDINFSPVVDFRYWMINTKGLKSDGDLIAPTTKMIIDSGTSLIVGPLDEVKRIATMMGAFSVPLMPEGMFFISCEKAKVLRDLQLEIEGQDYPIKIKDLLISASAAAGTPCLFGMMGLKALEGGRPTPQKNGFGIFPPSQLVASAKGPIGRTWILGDLFMRNVYTVFDYDNKQIGFARLKN
What is the function of this protein?
Aspartyl protease which is dispensable for protein degradation in the vacuolar compartment (VAC) or for tachyzoite and bradyzoite viability.
What are the official names of this protein?
Aspartic protease 1, TgASP1, Toxomepsin 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
Protein: THIE_AGRFC
Sequence: MNKVDYRLNALVDASLADVAPLPELALAAALNGATILQYRDKHGSTREMIENARAIREAIGGTGVPLVINDRVDVALASGADGVHLGADDMDAKTARRILGEKAIIGLTVKNRADAERAASMPADYACIGGVFETVSKVNPDKPVGIEGFTTLRALLKEWQPDMPVGAIAGIDLDRVPAVIAAGADGVAVISAIFRAANIASATSDFRSAIDAALKARQP
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: NDK_MYCPA
Sequence: MTERTLVLIKPDGVQRQLVGEIIGRIERKGLTLVALELRHVSQDLAAQHYAEHEGKPFFASLLEFITSGPVVAAIVEGPRAIAAFRQLAGGTDPVEKAIPGTIRGDFGLETQFNLVHGSDSVESAKREIGLWFPDA
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSB_VIBCM
Sequence: MSFTVVIPARYQSTRLPGKPLADIGGKPMIQWVYEQAMQAGADRVIIATDDERVEQAVQAFGGVVCMTSPNHQSGTERLAEVVAKMAIPADHIVVNVQGDEPLIPPAIIRQVADNLAACSAPMATLAVEIEDEAEVFNPNAVKVITDKSGYALYFSRATIPWDRDNFAKADKAIVQPLLRHIGIYAYRAGFINTYLDWQPSQLEKIECLEQLRVLWHGEKIHVAVALEAPPAGVDTPEDLEVVRRIVAERAQ
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_SALEP
Sequence: MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVVARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSREIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYDNTLTVYTTRPDTFMGATYLAVAAGHPLAQKAAANNAELAAFIDECRNTKVAEAEMATMEKKGVDTGFKATHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKPVILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIADKLAEKGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQELGGEGDIDNAPWPVADEQAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.