PharMolix/UniProtQA huggingface dataset:
Protein: ELP3_BOVIN
Sequence: MRQKRKGDLSPAQLMMLTIGDVIKQLIEAHEQGKDIDLNKVKTRTAAKYGLSAQPRLVDIIAAVPPQYRKVLVPKLKAKPIRTASGIAVVAVMCKPHRCPHISFTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPYLQTRHRIEQLKQLGHSVDKVEFIVMGGTFMALPEEYRDYFIRNLHDALSGHTSNNIYEAVKYSERSLTKCIGITIETRPDYCMKRHLSDMLTYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHLAKDSGFKVVAHMMPDLPNVGLERDIEQFTEFFENPAFRPDGLKLYPTLVIRGTGLYELWKSGRYKSYSPSDLIELVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELAFARMKDLGIQCRDVRTREVGIQEIHHKVRPYQVELVRRDYVANGGWETFLSYEDPDQDILIGLLRLRKCSEETFRFELVGGVSIVRELHVYGSVVPVSSRDPTKFQHQGFGMLLMEEAERIAREEHGSGKIAVISGVGTRNYYRKIGYRLQGPYMVKTLE
What is the function of this protein?
Catalytic tRNA acetyltransferase subunit of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) (By similarity).  In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (By similarity).  May also act as a protein lysine acetyltransferase by mediating acetylation of target proteins; such activity is however unclear in vivo and recent evidences suggest that ELP3 primarily acts as a tRNA acetyltransferase.  Involved in neurogenesis: regulates the migration and branching of projection neurons in the developing cerebral cortex, through a process depending on alpha-tubulin acetylation (By similarity).  Required for acetylation of GJA1 in the developing cerebral cortex (By similarity).
What are the official names of this protein?
Elongator complex protein 3, tRNA uridine(34) acetyltransferase.
What is the protein family that this protein belongs to?
Belongs to the ELP3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PETD_ACOCL
Sequence: MGVTKKPDLNDPVLRAKLAKGMGHNYYGEPAWPNDLLYIFPVVILGTIACNVGLAILEPSMIGEPADPFATPLEILPEWYFFPVFQILRTVPNKLLGVLLMASVPLGLFTVPFLENVNKFQNPFRRPVATTVFLIGTAVALWLGIGATLPIDKSLTLGLF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 4, 17 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetD subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ATP6_ESCF3
Sequence: MASENMTPQDYIGHHLNNLQLDLRTFSLVDPHNPPATFWTINIDSMFFSVVLGLLFLVLFRSVAKKATSGVPGKFQTAIELVIGFVNGSVKDMYHGKSKLIAPLALTIFVWVFLMNLMDLLPIDLLPYIAEHVLGLPALRVVPSADVNVTLSMALGVFILILFYSIKMKGIGGFTKELTLQPFNHWAFIPVNLILEGVSLLSKPVSLGLRLFGNMYAGELIFILIAGLLPWWSQWILNVPWAIFHILIITLQAFIFMVLTIVYLSMASEEH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS16A_ARATH
Sequence: MTVKIRLARLGCKHRPFYRVVVADEKSRRDGKQIEVLGFYDPLQGKEDADRVSLKFDRIKYWLSVGAQPTDTVESMLFRAGLIPPKPMVVVGSKNGQKSTSQHVSPITGEILN
What are the official names of this protein?
30S ribosomal protein S16-1, chloroplastic, Small subunit ribosomal protein 16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YQJG_ECOLI
Sequence: MGQLIDGVWHDTWYDTKSTGGKFQRSASAFRNWLTADGAPGPTGTGGFIAEKDRYHLYVSLACPWAHRTLIMRKLKGLEPFISVSVVNPLMLENGWTFDDSFPGATGDTLYQNEFLYQLYLHADPHYSGRVTVPVLWDKKNHTIVSNESAEIIRMFNTAFDALGAKAGDYYPPALQTKIDELNGWIYDTVNNGVYKAGFATSQEAYDEAVAKVFESLARLEQILGQHRYLTGNQLTEADIRLWTTLVRFDPVYVTHFKCDKHRISDYLNLYGFLRDIYQMPGIAETVNFDHIRNHYFRSHKTINPTGIISIGPWQDLDEPHGRDVRFG
What is the function of this protein?
Catalyzes glutathione (GSH)-dependent reduction of glutathionyl-hydroquinones (GS-HQs) to the corresponding hydroquinones.  Can use a variety of GS-HQs as substrates, such as GS-p-hydroquinone (GS-HQ), GS-hydroxy-p-hydroquinone (GS-HHQ), GS-methyl-p-hydroquinone (GS-MHQ), GS-menadiol, and GS-trichloro-p-hydroquinone (GS-TriCH).  Also displays GSH-dependent disulfide-bond reduction activity toward HED (2-hydroxyethyl disulfide), and is able to catalyze DMA (dimethylarsinate) reduction.  Exhibits no GSH transferase activity with 1-chloro-2,4-dinitrobenzene (CDNB).
What are the official names of this protein?
Glutathionyl-hydroquinone reductase YqjG, GS-HQR.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Xi-class GSH transferase family.
Protein: CYVD_LEOCM
Sequence: GFPCGESCVFIPCISAAIGCSCKNKVCYRN
What is the function of this protein?
Probably participates in a plant defense mechanism.  Has anti-HIV activity.
What are the official names of this protein?
Cycloviolin-D.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Bracelet subfamily.
Protein: SRTM1_HUMAN
Sequence: MSEPDTSSGFSGSVENGTFLELFPTSLSTSVDPSSGHLSNVYIYVSIFLSLLAFLLLLLIIALQRLKNIISSSSSYPEYPSDAGSSFTNLEVCSISSQRSTFSNLSS
What are the official names of this protein?
Serine-rich and transmembrane domain-containing protein 1.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: HTPX_HAEIG
Sequence: MMRILLFLATNMAVMLVLGIILSVTGIAGNSTGGILIMALLFGFAGSLISLFLSKTMALRSVDGEVITQPRNQTERWLIDTVSRQAQKAGIPMPDVAIYHSPDVNAFATGATKSNSLVAVSTGLLNNMTEAEAEAVLAHEISHISNGDMVTMALLQGVLNTFVIFLSRVIATAVASSRNNNGEETRSSGIYFLVSMVLEMLFGVLASIIAMWFSRYREFRADAGSASLVGKEKMIMALQRLQQLHEPQNLEGSLNAFMINGKRSELFMSHPPLEKRIEALRNL
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VIE1_HCMVT
Sequence: MESSAKRKMDPDNPDEGPSSKVPRPETPVTKATTFLQTMLRKEVNSQLSLGDPLFPELAEESLKTFERVTEDCNENPEKDVLAELVKQIKVRVDMVRHRIKEHMLKKYTQTEEKFTGAFNMMGGCLQNALDILDKVHEPFEEMKCIGLTMQSMYENYIVPEDKREMWMACIKELHDVSKGAANKLGGALQAKARAKKDELRRKMMYMCYRNIEFFTKNSAFPKTTNGCSQAMAALQNLPQCSPDEIMAYAQKIFKILDEERDKVLTHIDHIFMDILTTCVETMCNEYKVTSDACMMTMYGGISLLSEFCRVLSCYVLEETSVMLAKRPLITKPEVISVMKRRIEEICMKVFAQYILGADPLRVCSPSVDDLRAIAEESDEEEAIVAYTLATRGASSSDSLVSPPESPVPATIPLSSVIVAENSDQEESEQSDEEEEEGAQEEREDTVSVKSEPVSEIEEVAPEEEEDGAEEPTASGGKSTHPMVTRSKADQ
What is the function of this protein?
Plays an important role in transactivating viral early genes as well as activating its own promoter, probably by altering the viral chromatin structure (PubMed:17331553, PubMed:8876134, PubMed:23878222, PubMed:15572445, PubMed:26812545).  Expression of IE1 and IE2 proteins is critical for the establishment of lytic infection and reactivation from viral latency (By similarity).  Disrupts PML-associated ND10 nuclear bodies by interfering with host PML and SP100 sumoylation thereby altering the regulation of type I and type II interferon-induced gene expression (PubMed:9151854, PubMed:15163746, PubMed:17367754, PubMed:10233977).  Promotes efficient viral growth by interacting with and directing host SP100 to degradation, leading to enhanced acetylation level of histones (PubMed:21880768).  In addition, functions in counteracting the host innate antiviral response.  Inhibits the type I interferon pathway by directly interacting with and sequestrating host STAT2 (PubMed:18701593, PubMed:19812155, PubMed:16497831).  Also targets type II interferon pathway by repressing IL6- and STAT3 target genes (PubMed:27387064).  Repression of STAT3 genes is due to STAT3 nuclear accumulation and disruption of IL6-induced STAT3 phosphorylation by IE1 (By similarity).  This repression is followed by phosphorylation and activation of STAT1 (PubMed:27387064).  Inhibits host ISG transcription by sequestering host ISGF3 in a PML- and STAT2- binding dependent manner (PubMed:25812002).  Alters host cell cycle progression, probably through its interaction with host E2F1 or RB1 that overcomes the RB1-mediated repression of E2F-responsive promoters (PubMed:8892909).
What are the official names of this protein?
Immediate early protein IE1, IE1, 55 kDa immediate-early protein 1, IE1p72, IE72.
What is the protein family that this protein belongs to?
Belongs to the HHV-5 IE1 protein family.
What are the subcellular locations of this protein?
Host nucleus. Note=Colocalizes with host PML-associated nuclear bodies very early post infection.
Protein: MRS21_ARATH
Sequence: MSELKERLLPPRPASAMNLRDASVTRPSASGRPPLLGVDVLGLKKRGQGLRSWIRVDTSGNTQVMEVDKFTMMRRCDLPARDLRLLDPLFVYPSTILGREKAIVVNLEQIRCIITADEVLLLNSLDNYVLRYVVELQQRLKTSSVGEMWQQENSQLSRRRSRSFDNAFENSSPDYLPFEFRALEIALEAACTFLDSQASELEIEAYPLLDELTSKISTLNLERVRRLKSRLVALTRRVQKVRDEIEQLMDDDGDMAEMYLTEKKRRMEGSMYGDQSLLGYRSNDGLSVSAPVSPVSSPPDSRRLDKSLSIARSRHDSARSSEGAENIEELEMLLEAYFVVIDSTLNKLTSLKEYIDDTEDFINIQLDNVRNQLIQFELLLTTATFVVAIFGVVAGIFGMNFEIDFFNQPGAFRWVLIITGVCGFVIFSAFVWFFKYRRLMPL
What is the function of this protein?
Magnesium transporter that may mediate the influx of magnesium.
What are the official names of this protein?
Magnesium transporter MRS2-1, Magnesium Transporter 2, AtMGT2.
What is the protein family that this protein belongs to?
Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35.5) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ARSC_BACC3
Sequence: MENKKTIYFLCTGNSCRSQMAEAWGKQYLGDKWNVYSAGIEAHGVNPNAIKAMNEVNIDITNQTSDMIDINILNNADLVVTLCSHADSVCPSTPPHVNRVHWGFDDPAGKEWSEFQRVRDEIRERIKRFSEIGE
What is the function of this protein?
Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)].
What are the official names of this protein?
Arsenate reductase.
What is the protein family that this protein belongs to?
Belongs to the low molecular weight phosphotyrosine protein phosphatase family. Thioredoxin-coupled ArsC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHAS_SALDC
Sequence: MTVLHSVDFFPSGKAPVAIEPRLPQAAFPEHHHDFHEIVIVEHCTGIHVFNGQPYTISGGTVCFVRDHDRHLYEHTDNLCLTNVLWRSPDAFQFLAGLEQLLPQEQDGYYPSHWRVNQSALQQVRQLVGLMERAGDGMDAPAVANREILFMQLLVLLRRSSLMEGATNNDAKLNQLMAWLEDHFAEEVCWEAVAEQFSLSLRTLHRQLKQHTGLTPQRYLNRLRLIKARHLLRHSDHSVTEIAYRCGFGDSNHFSTLFRREFNWSPRDIRQGRDAIIQ
What is the function of this protein?
Activates expression of the rhaBAD and rhaT operons.
What are the official names of this protein?
HTH-type transcriptional activator RhaS, L-rhamnose operon regulatory protein RhaS.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GMT1_YEAS2
Sequence: MSELKTGHAGHNPWASVANSGPISILSYCGSSILMTVTNKFVVNLKDFNMNFVMLFVQSLVCTITLIILRILGYAKFRSLNKTDAKNWFPISFLLVLMIYTSSKALQYLAVPIYTIFKNLTIILIAYGEVLFFGGSVTSMELSSFLLMVLSSVVATWGDQQAVAAKAASLAEGAAGAVASFNPGYFWMFTNCITSALFVLIMRKRIKLTNFKDFDTMFYNNVLALPILLLFSFCVEDWSSVNLTNNFSNDSLTAMIISGVASVGISYCSGWCVRVTSSTTYSMVGALNKLPIALSGLIFFDAPRNFLSILSIFIGFLSGIIYAVAKQKKQQAQPLRK
What is the function of this protein?
Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.  Defective copy causes severe glycosylation defect and abnormal retention of soluble endoplasmic reticulum proteins.  Involved in vanadate sensitivity (By similarity).
What are the official names of this protein?
GDP-mannose transporter 1, GMT 1, Low dye-binding protein 3, Morphogenesis checkpoint-dependent protein 3, Vanadate resistance glycosylation protein 4.
What is the protein family that this protein belongs to?
Belongs to the TPT transporter family. SLC35D subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Recycles between the Golgi apparatus and the endoplasmic reticulum.
Protein: MPH2_YEAST
Sequence: MKNLSFLINRRKENTSDSNVYPGKAKSHEPSWIEMDDQTKKDGLDIVHVEFSPDTRAPSDSNKVITEIFDATEDAKEADESERGMPLATALNTYPKAAAWSLLVSTTLIMEGYDTAILGAFYALPIFQRKFGSQNDKTGEWEISASWQIGLTLCYMAGEIVGLQLTGPSVDLVGNRYTLIIALFFLAAFTFILYFCNSLGMIAVGQALCGMPWGCFQCLTVSYASEICPLALRYYLTTYSNLCWLFGQLFAAGIMKNSQKKYADSELGYKLPFALQWILPVPLALGIFFAPESPWWLVKKGRFDEARRSLRRTLSGKGPEKEILVTLEVDKIKVTIDKEKRLTSKEGSYSDCFEDKINRRRTRITCLCWAGQATCGSILIGYSTYFYEKAGVSTEMSFTFSIIQYCLGICATFLSWWASKYFGRYDLYAFGLAFQTIVFFIIGGLGCSSTHGSKMGSGSLLMAVAFFYNLGIAPVVFCLVSEMPSSRLRTKTIILARNTYNVVSIICSVLILYQLNSKKWNWGAKSGFFWGVLCFCTLIWAVVDLPETAGKTFVEINELFKLGVSARKFKSTKVDPFVVKTPLKTSLITTPREISKLPLQRNSNVSHHL
What is the function of this protein?
High-affinity uptake of maltose and maltotriose.  Also transports alpha-methylglucoside, glucose and turanose but not melezitose or trehalose.
What are the official names of this protein?
Alpha-glucosides permease MPH2, Maltose transport protein 2.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYGA_HAEDU
Sequence: MSTKFNVKTFQGMILALQEYWANVGCTIVQPFDMEVGAGTSHPMTALRALGPEPMAFAYVQPSRRPTDGRYGENPNRLQHYYQFQVVIKPSPDNIQELYLGSLKMLGFDPTQHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECKPVTGEVTYGLERLAMYIQGVDSVYDLVYSDGPLGKTTYGDVFHQNEVEQSTYNFEYADVDFLFKAFEQYEKEAQELLALEKPLPLPAYERVLKAAHSFNMLDARKAISVTERQRYILRIRALTKGVAEAYYASREALGFPGCNK
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXA_SYNY3
Sequence: MDCMSLPRLILTLGDPAGIGPEVVLKALAEPGLASICQLTAIGSRSVLDQTRRQLLAQNPGLNLADPETINLLEVDLSYLGKITVGQGDAVSGAISFAYLNEAITRTLAGEFDAIVTAPIAKSAWQAAGHNYPGQTEVLAHRAGVESFAMAFVGRSPFTGWTLRTLLATTHIPLKEVPQALTPQLMTAKLELLLTCLAQDFGISNPSVAIAGLNPHSGEEGKLGSEEQDWLIPWLEQARKKYPQAQLIGPIPPDTMWVGPGKAWLTDGQTTVSDAYLALYHDQGLIPVKLLAFDQAINTTIGLPFVRTSPDHGTAFDIAGQGIARADSLIAAIKLAAELVEQRCRPRAQ
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS_MARMS
Sequence: MSKTPADNHTPMMRQYFGLKSQHPNQLLFYRMGDFYELFYDDAKRASRLLDITLTARGHSGGIPIPMAGIPYHAAENYIARLVRMGESVVVAEQTGDPATSKGPVERQIARIVTPGTISDEAFLEEKRENLLLSLAHQSRKGLDIFGFSYLDMASGRFCLFEVDGHEALSSELQRLSPREILISEDFPARATLKLEKGISELGPWHFDYESSYRQLIQQFSTKDLSGFGCEAMTAAIASAGALLQYAKDTQRSALPHIQSIMVEHKDDSVLIDGATRRNLEIDINLTGGTSNTLVEVLDKCSTPMGSRLLKRWLHTPIRDLNEIQARQQVVAELQQNQSYNAFEAPLKKVGDLERILSRVALRSARPRDLLRLRFALEAAPEINGLLANATSERLQELNLRILAQPIITETLAKALVENPPSVVRDGGIFAKGYDEELDELLALSTNATDFLAEMERSEKARTGISSLKVGFNRVHGYYIEISRLHSDQAPVEYIRRQTLKNAERFITPELKAFEDKALSAKSKSLAREKELYEALLEQLNEILGELQTTSQALAQLDVLNNFAERANALSFTCPELHNRGGIQIVGGRHPVVESVISEPFVPNDLDLNDKRSLLMITGPNMGGKSTYMRQIALITLLAHTGCFVPAESASISVVDRIFTRMGSSDDLAGGRSTFMVEMTETANILNNASKNSLVLMDEVGRGTSTFDGLSLAWAAVDYLANKLKCYVLFATHYFELTTLADQLENAANVHLTATEYEDEIVFLHKVHEGPASQSYGLQVAQLAGVPRDVIGHAKQKLKELEVVTGIDLDTKTIETKANSSSIKAKTKEHLVKESKNGYQPQQVDMFAQAEQNALKNALEELDLDNMTPLEAISALYKLKSQL
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: ATPG_STRU0
Sequence: MAGSLSEIKAKINSTEKTSKITSAMRMVSSAKLVKSEQSARDFQIYASKIRQITTDLLKAELTSGSTNPMLVSRPVKKTGYIVITSDKGLVGGYNSKILKSVMEMIEEYHADGSYSIISIGSVGSDFFKARGMNVSFELRGLADQPSFEEVGKIISQSVAMYQNEIFDELYVCYNHHVNSLTSQVRVQQMLPISDLVAEEANDEGVVGFELEPDRDTILNQLLPQFTESLIYGAIIDAKTAEHAAGMTAMQTATDNAKNVINDLTIQYNRARQAAITQEITEIVAGANALE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ACKA_METBF
Sequence: MKVLVINAGSSSLKYQLIDMINESPLAVGLCERVGIDNSIITQKRFDGKKLEKQVDLPTHRVALEEVVKALTDPEFGVITDMGEINAVGHRVVHGGEKFTTSALFDAGVEEAIRDCFDLAPLHNPPNMMGISACAEIMPGTPMVIVFDTAFHQTMPAYAYMYALPYDLYEKYGVRKYGFHGTSHKYVAGRAALMLGKPIEDTKIITCHLGNGSSIAAVKGGKSIDTSMGFTPLEGVAMGTRCGSIDPAVVPFVMDKESLSSREVDTLMNKKSGVLGVSGISNDFRDLDEAASHGNERAELALEIFAYSVKRVIGEYLAVLNGADAIVFTAGIGENSASIRKRILTGLEGLGIKIDEEKNKIRGQEIDISTPDSSIRVFVIPTNEELAIARETKEIVETEAKLRKSVPV
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS21_NEIMA
Sequence: MPAIRVKENEPFEVAMRRFKRAVEKTGLLTELRAREAYEKPTTERKRKKAAAVKRLQKRLRSQQLPPKMY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: REXO4_DICDI
Sequence: MRKTVRKNKQVKRELALLEKEKEEIESFTKVSKTVENKQSINSNWNVTKEKIKNKNNAYQKKKEAKLKLKSATPYTSTKVIEEKKPHIKDFNQLCQEHNIISPIDDNLVSPTQKEIDNLNESSKFFSIDCKIIEIEGNKGTLGKVCIANQNGQIIYEKIVKPMDKIVDFRTKFTGLTRDKVQREGTDFLQVQKEVEKILRHKILVGHDLVHDLKNLKLAHKKKLLRDATQFTKFFNPDTNSEDSLKSIAKRELNFSPDNWDPNGKRDTIINVILYKQNQKEWEAFINNKFYGQPIDKN
What are the official names of this protein?
RNA exonuclease 4.
What is the protein family that this protein belongs to?
Belongs to the REXO4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: AKR1_NAUCC
Sequence: MSDINTESGESTSLPNSTDPPLSDVNIDVEDDDTAESISSLQPIVSNTTNPPEEPINPVLGQYHQACQKGDLATVKQLLDSGVLDLNTDLTGDITGLHWASINNRLSVVKYLISQGIDVNAKAGDLEATPLHWAARYGYVHIVDCLLNKGADPTMCDMQGFNLLHLAVNSSNVMLVAYVLFFVVAKGIIDIDCQDPKGRTPLLWAAYQGDSLSVMLLLKFGASTKIVDEGGFTPLHWATVKGQPYVLTHLIRDGADFFLKTNDGKDCFTIAQEMNTSHSFKDALSICGFNQDGYPKRKLFKKSDHAKVITFFVPLVALSIIFILFTHLHPLFALLISLIFGLAVNKALKELILPSYSNYGLHSTSLLKSPFLSGTFFGSLLLLTIVWIFKIAPFTIFKSRLLTNFFMFLILMQIYYLFIKLIFSDPGCVPIETDHENVRGTIKELLDTGKFDIKNFCLETWIRKPLRSHFSTLNTHNVARFDHFCPWIYNDIGLKNHKNFMWFILLTEVGIWFFISLTMKYFDILEDTNEDVACFLLGDDELCAGFVYDRFTFLIALWALIQSVWVGFLIVVQVFQTFTGVTNKEFNKYVKEKKNQHAFDPIFFNDTFNTTPEELRNDDDDTAASRTGNNPNHSNGTTIPSEGSRINTRKPRTCFNLCFAITGLDQVRTIVRETLGIGGANEMSRMQLLSSIPTNYGWKRNLADFWLTSDVMAPIWRRLFYSPVESRALLNGVEVDYFKLYDFPEKTYPEPTGPESV
What is the function of this protein?
Palmitoyltransferase specific for casein kinase 1.
What are the official names of this protein?
Palmitoyltransferase AKR1, Ankyrin repeat-containing protein AKR1.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.
What are the subcellular locations of this protein?
Early endosome membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: TIG_YERPN
Sequence: MQVSVETTQGLGRRVTITVAADSIEKAVKSELVKAAKNVRIDGFRKGHVPMNIVEQRYGASVRQDVLGDLMQRNFVDAIIKEKINPAGAPNYVPGEYKQGEDFTYSVEFEVYPEVELKDLESIEVEKPVVEVNDADVDTMLETLRKQQATWKETDAAATAEDRATLDFTGSIDGEEFEGGKATDFVLAMGQGRMIPGFEEGVIGHKAGEEFTIDVNFPEDYHAENLKGKSAKFAIVLKKVEVRELPELTEEFIKRFGVADGSLAGLRAEVRKNMERELKGAVRNRVKTQAIDGLVSANNIDVPTALVDGEIDVLRRQAAQRFGGNEKQAAELPRELFEEQAKRRVVVGLLLGEVISQHELKADEDRVKALIEEMASAYEDPQEVIEFYSKNKELMNNMRNVALEEQAVETLLAKAKVTEKPTTFSELMNQTTAA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: RSGA_CLOBK
Sequence: MKGTIIKGIGGFYYIKIDNSEEIIECKARGKFRHTELTPMIGDYVEISIDKNNKGAIEKIYERRSELFRPAVANVTQALVVFSFKNPDINIDLLNKFLLLCEYNNLKAIVCFNKMDLVNKEDYKDIISMIEQAGYDIIFLNAEKERNMDIIKKLIKDNVTVFCGPSGVGKSTMLNKIIGKETMITGNISEKLKRGKHTTRHSELIYVDEGLLVDTPGFSSLDINFMEKEDLLHCIPEFRDFIGECKFTGCLHHREPNCAVKKAVEEGHIHKNRYDFYIKTLEEFMNRRKKKW
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYI_HYDS0
Sequence: MDYKDTINLPKTDFPMKANLSEKELEILKKWEGLYEKLRAQRKGKQLFVLHDGPPYANGNIHIGHALNKILKDIICKVALIEGFDVDYKPGWDCHGLPIEQQVEKELKAKKINKESMPKDEFRRLCREYASKFVSIQKEEFLRLGVLGDWENPYLTMDPKYEAQEVREIGRCLQNGVLYKGNKPVYWCIYDKTAEAEAEVEYKEKKDISIYVRFELLKQSENVLRQKLDLPDKPISIVIWTTTPWTLPANLGVMSSEDIEYVVVEEDNYLLLLEKQSQYVKNKEFIASLKGKELTGLEYQHPFIERTGKIYPSEFVEAGTGTGFVHMAPGHGMEDYIVGLRYGLEPFSPVDESGRFTEEAPEFIRGLNVFEANTVIIEHLKQTGFLLKEEEILHSYPHCWRCKNPVIYRATPQWFIGVDRAITSHFASCEDEKIDTSDVKKLQNKSIREKAIEETYNVKWVPKTGQNRMLSMLQNRPDWCISRQRFWGVPITIFYCKRCGEPLLESHIFEHVAKIFESSPYGADEWFKKDEKELLPPDTVCKKCGSKDFVKETDILDVWFDSGSSHASVLRPRGIEKADVYLEGSDQHRGWFQASLLESIASYGEAPFKSVVTHGFTVDEKGHKMSKSQGNVISPLEIIKEYGADILRLWVISEDYTEDIKLGKSILKRLAEDYKKIRNTLRYCLGNLYDFKYEFSIAPDKLHHFDRYMYAYASKVFEELFSFYKNYQYHRFYHRLMEFVSIDLSALYFDVLKDRLYMYKSGSFERLSAQTVLYFLLKNLTILLSPVLSFTAEETYSYMKSIENHLPESIFMNEYKASDFTDEELLKDYQKLLLLRKDVLKAIEIERKNDIIKHPYEARVVIKPNEEFYKLLEKYKDYLHSFFTVSQVEIAENDGEEGEYTKLRIKVEKAKGEKCPRCWLYVETMINGVCPRCSQNI
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.