PharMolix/UniProtQA huggingface dataset:
Protein: FABH_CLOP1
Sequence: MKNAKMIGFGLYTPKNLVENERLQEFLETSDEWIRTRTGIERRYISLDENTSDLAVEASKKALNQAGLSAEDIDLIILATVTPDNFTPSTACIVQDKLGAKNAWAFDINAACTGFIYALKLGRSLIRSGEAKNALIIGAETLSKALNWEDRGSCVLFGDGAGATVLTSTEEDCGIKCVNVKSDGSKGDSLVIQGLPLNSPFKDGREVSENYINMNGREIFKFATKVMEESIVEILEKENIKIEDIDAIIPHQANLRIIDYVVKRLGIPREKFITNLQNYGNTSGASIPIALCESINEGNLKKGDNIIMVGFGGGLTWGAALIKL
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSDA_MYCBO
Sequence: MREFGNPLGDRPPLDELARTDLLLDALAEREEVDFADPRDDALAALLGQWRDDLRWPPASALVSQDEAVAALRAGVAQRRRARRSLAAVGSVAAALLVLSGFGAVVADARPGDLLYGLHAMMFNRSRVSDDQIVLSAKANLAKVEQMIAQGQWAEAQDELAEVSSTVQAVTDGSRRQDLINEVNLLNTKVETRDPNATLRPGSPSNPAAPGSVGNSWTPLAPVVEPPTPPTPASAAEPSMSAGVSESPMPNSTSTVAASPSTPSSKPEPGSIDPSLEPADEATNPAGQPAPETPVSPTH
What is the function of this protein?
An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigD.  ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP).  RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses.  The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P), while cytoplasmic proteases finish degrading the regulatory protein, liberating the sigma factor.  Neither S1P nor S2P proteases have been so far identified for this anti-sigma factor (By similarity).
What are the official names of this protein?
Anti-sigma-D factor RsdA, Regulator of SigD, Sigma-D anti-sigma factor RsdA.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RECA_VIBA7
Sequence: MDENKQKALAAALGQIEKQFGKGSIMRLGDNRTMDVETISTGSLSLDIALGAGGLPMGRIVEVYGPESSGKTTLTLELIAAAQRVGKTCAFIDAEHALDPIYAKKLGVNIDELLVSQPDTGEQALEICDALARSGAIDVIVIDSVAALTPKAEIEGEMGDSHMGLQARMLSQAMRKLTGNLKQSNCMCIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRTGSIKEGDEVVGNETRIKVVKNKIAAPFKQADTQILYGQGFNREGELVDLGVKHKLVEKAGAWYSYNGDKIGQGKANACKFLRENPAAAMALDTKLREMLLNPAELIVEEPILSEMPQEEEL
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX2_SITGR
Sequence: MSTWKNLFLQDSASPLMELLMCFHDHAMLILILITIMVSQMLLSMLFNKLSHRYLLEGQLIETIWTIIPAIILILIALPSLRLLYILDEINNPQLLIKIIGHQWYWSYEYSDYKNIEFDSYMIPTKELNSFNFRLLEVDNRTPIPYKTQIRILVTSADVIHSWTIPSMSIKIDGTPGRLNQANLIANRSSIFFGQCSEICGANHSFMPIVLESITPNLFLNWVISKA
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DNLJ_KINRD
Sequence: MDTVDGGDVPSEARHRWEDLVAQIEAARFAYYVRNSSPLSDGQYDALERELRALEEQHPQLRTPDSPTQTVGGTFSTEFTTVDHPERMLSLDNAFSTDELSAWAARVEREVGAGARYLCEPKIDGLAIDLVYEDGRLVRGVTRGDGRTGEDVTFNVRTVEDVPHRLTGADVPEFLEVRGEVFFHLDGFAAINAGLVEAGKPPFANPRNAAAGSLRQKDPRVTATRPLRMLVHGVGARRGMENDTQSGAYEKLAAWGLPTSPRVKVVDTLDEVAEYVRFYGEHRHDVEHEIDGVVVKVDQVPLQRRLGSTSRAPRWAIAYKYPPEEVTTSLLDIQVNVGRTGRVTPFAVLEPVKVAGSTVAMATLHNASEVVRKGVLIGDTVVVRKAGDVIPEVLGPVVESRTGAEREFVMPTVCPECGTPLAHQRADDVDIRCPNSRSCPAQLRERVFHLAGRGSFDVEALGDKAAAALLQAGVIADEGDLFTLTEDDLVGVPLFTTKAGTVSANGRRLLANLHDRKDQPLWRVLVGLSIRHVGPTAARALADRFGSMEAIEAATAEDIASAEGVGPTIAEAVVEWLAVDWHRDVVRKWREAGVRMADERDESTPRTLEGLTIVVTGSLSGFSRDEAKEAVLSRGGKASSAVSKKTSFVVVGEAAGSKADKAEQLGVPVLDEEGFVALLEGGPDAVARPAEEPGQG
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: Y4175_RICAH
Sequence: MAGHSKFKNIQHRKCAQDKKRAKVFTKLIREIVTAVKTGSSNIPENNPRLRNALTAARSQNLPKERIDKAINSADDANTENYTEIRYEGYAPNGIAIIVEALTDNKNRTAAEVRSSFTKYGGSLGETGSVNYLFKHCGVIQYPTNIASNEDIFEAAIEAGGDDIVSDAIFHTICTDIENFSKVLEFLTGKYGIPEDSYIGWIPLNTIIIDDTEKAEKLLKLVEALEESDDVQRVFSNYEFSDDVYEIIQGEE
What are the official names of this protein?
Probable transcriptional regulatory protein A1C_04175.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPC6_HUMAN
Sequence: MSQSPAFGPRRGSSPRGAAGAAARRNESQDYLLMDSELGEDGCPQAPLPCYGYYPCFRGSDNRLAHRRQTVLREKGRRLANRGPAYMFSDRSTSLSIEEERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRVGDALLLAISKGYVRIVEAILSHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCNDCNQKQKHDSFSHSRSRINAYKGLASPAYLSLSSEDPVMTALELSNELAVLANIEKEFKNDYKKLSMQCKDFVVGLLDLCRNTEEVEAILNGDVETLQSGDHGRPNLSRLKLAIKYEVKKFVAHPNCQQQLLSIWYENLSGLRQQTMAVKFLVVLAVAIGLPFLALIYWFAPCSKMGKIMRGPFMKFVAHAASFTIFLGLLVMNAADRFEGTKLLPNETSTDNAKQLFRMKTSCFSWMEMLIISWVIGMIWAECKEIWTQGPKEYLFELWNMLDFGMLAIFAASFIARFMAFWHASKAQSIIDANDTLKDLTKVTLGDNVKYYNLARIKWDPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYIGAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYGVYNVTMVIVLLNMLIAMINSSFQEIEDDADVEWKFARAKLWFSYFEEGRTLPVPFNLVPSPKSLFYLLLKLKKWISELFQGHKKGFQEDAEMNKINEEKKLGILGSHEDLSKLSLDKKQVGHNKQPSIRSSEDFHLNSFNNPPRQYQKIMKRLIKRYVLQAQIDKESDEVNEGELKEIKQDISSLRYELLEEKSQNTEDLAELIRELGEKLSMEPNQEETNR
What is the function of this protein?
Thought to form a receptor-activated non-selective calcium permeant cation channel (PubMed:19936226, PubMed:23291369).  Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors.  Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C (PubMed:26892346).  Seems not to be activated by intracellular calcium store depletion.
What are the official names of this protein?
Short transient receptor potential channel 6, TrpC6, Transient receptor protein 6, TRP-6.
What is the protein family that this protein belongs to?
Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC6 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TAM_STRGL
Sequence: MALTQVETEIVPVSVDGETLTVEAVRRVAEERATVDVPAESIAKAQKSREIFEGIAEQNIPIYGVTTGYGEMIYMQVDKSKEVELQTNLVRSHSAGVGPLFAEDEARAIVAARLNTLAKGHSAVRPIILERLAQYLNEGITPAIPEIGSLGASGDLAPLSHVASTLIGEGYVLRDGRPVETAQVLAERGIEPLELRFKEGLALINGTSGMTGLGSLVVGRALEQAQQAEIVTALLIEAVRGSTSPFLAEGHDIARPHEGQIDTAANMRALMRGSGLTVEHADLRRELQKDKEAGKDVQRSEIYLQKAYSLRAIPQVVGAVRDTLYHARHKLRIELNSANDNPLFFEGKEIFHGANFHGQPIAFAMDFVTIALTQLGVLAERQINRVLNRHLSYGLPEFLVSGDPGLHSGFAGAQYPATALVAENRTIGPASTQSVPSNGDNQDVVSMGLISARNARRVLSNNNKILAVEYLAAAQAVDISGRFDGLSPAAKATYEAVRRLVPTLGVDRYMADDIELVADALSRGEFLRAIARETDIQLR
What is the function of this protein?
Involved in the biosynthesis of the enediyne antitumor antibiotic C-1027.  Catalyzes the MIO-dependent deamination of L-tyrosine generating the corresponding alpha,beta-unsaturated acid, (S)-beta-tyrosine.
What are the official names of this protein?
MIO-dependent tyrosine 2,3-aminomutase, Tyrosine ammonia-lyase.
What is the protein family that this protein belongs to?
Belongs to the TAL/TAM family.
Protein: TRMB_LACPL
Sequence: MRVRNKPWAPKLIAAHPELITEDPTQLKGRWQSRFAKPQPLQIEVGSGKGQFIIEMAKRHPEINYVAIEIQTSVIAIILKKLVEAPLPNLQLAHADGQAVTAFFEPHEVDRLYLNFSDPWPKSRHEKRRLTYKSFLSSYREVLKPNGQIEFKTDNRGLFEFSLTSMNNFGMQFEQVWLDLHAVATPEDNVETEYEQKFSAAGPIYKIIATFPAK
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: PYRH_SYNSC
Sequence: MTYTRVLLKLSGEALMGSQGYGIDPAIVQSIASDVAKVVANGTQLAIVVGGGNIFRGLKGSAAGMERATADYVGMLATVMNAITLQDGLERAGVPTRVQTAIAMQEVAEPYIRRKAIRHLEKNRVVVFGAGCGNPFFTTDTTAALRAAEINADVVFKATKVDGVYDKDPAKHADAVKHPQLSYQDVLSGELGVMDSTAIALCKDNNIPIVVFNLFEPGNIGRAVAGEPIGSRIGDPA
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINC_BRUA4
Sequence: MNQVLTQSRPIRLKGRSFLALVLSPELPLDGWLDKLDDLAARSVGFFLNRPIVLDLENVSIERPQLVQLLEDLVKRGVWITGFENARPSLLGPGMPPAMRGGQPAADFDPEITEPKSQERTPVAPASVQLVKAVPSMVVTEPVRSGQSVYFPDGDVTIVGSVASGAEVVAGGSIHVYGALRGRAMAGTAGNADARIFCRKMEAELVAIDGLYKTAEDMESRLRGQAVQLWLDGDYMMAETLN
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: ARTQ_BACSU
Sequence: MNLDFSATIPQIPFILEGLAITLKIVVVSAIIGLILGIVLSLCKISTFRPFIWIADFYTSVFRGTPLVLQLMIVYFGLPQLLGFQIDQFWAAVVALSLNSAAYVSEIIRAGINAIDKGQKEAAVALGVPYGKMMKDLLLPQAFKNISPAIVNELITLTKESAIVTVIGLGDVMRRAYQAGAATYNYLEPLIIAGLIYYVLVLILTFIGKAVERKLKSND
What is the function of this protein?
Part of a binding-protein-dependent transport system for arginine.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Arginine transport system permease protein ArtQ.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HAT7_ARATH
Sequence: MYMYEEERNNINNNQEGLRLEMAFPQHGFMFQQLHEDNAHHLPSPTSLPSCPPHLFYGGGGNYMMNRSMSFTGVSDHHHLTQKSPTTTNNMNDQDQVGEEDNLSDDGSHMMLGEKKKRLNLEQVRALEKSFELGNKLEPERKMQLAKALGLQPRQIAIWFQNRRARWKTKQLERDYDSLKKQFDVLKSDNDSLLAHNKKLHAELVALKKHDRKESAKIKREFAEASWSNNGSTENNHNNNSSDANHVSMIKDLFPSSIRSATATTTSTHIDHQIVQDQDQGFCNMFNGIDETTSASYWAWPDQQQQHHNHHQFN
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
Homeobox-leucine zipper protein HAT7, HD-ZIP protein ATHB-3, Homeodomain transcription factor ATHB-3, Homeodomain-leucine zipper protein HAT7, HD-ZIP protein 7.
What is the protein family that this protein belongs to?
Belongs to the HD-ZIP homeobox family. Class I subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: US426_GAHVG
Sequence: MLLVVADVILTSLYLSSSGDFKYESLKLLGKFETCCIDVSTTIGRCLPPFRSSHCFTFSSWALGVPVRTMSNSRVVPLTKKLNGLHSLLSFIPRLEKLHVPLTVSNMSLEMGSPLIIIKRVYNPLSSRLGAAIINFNSSRSI
What are the official names of this protein?
Uncharacterized 15.7 kDa protein.
Protein: LECA_CYMRO
Sequence: ADTIVAVELDSYPNTDIGDPSYPHIGIDIKSIRSKSTARWNMQTGKVGTAHISYNSVAKRLTAVVSYSGSSSTTVSYDVDLNNVLPEWVRVGLSATTGLYKETNTILSWSFTSKLKTNSIADANALHFSFHQFTQNPKDLILQGDATTDSDGNLELTKVSSSGSPQGSSVGRALFYAPVHIWESSAVVASFDATFTFLIKSPDSEPADGITFFIANTDTSIPSGSSGRLLGLFPDAN
What is the function of this protein?
D-mannose/D-glucose-binding lectin.  Also binds derivatives of glucose and mannose such as more complex glycans.
What are the official names of this protein?
Mannose-specific lectin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the leguminous lectin family.
Protein: Y057_BUCAP
Sequence: MKKKLINFKNALVLVVGDLILDCYWYSKNYYVVLEESLPIASINKIKKQPGGAANVAKNIAEIGGNSKIIGFIGMDYEGLTLKKLLNHTRIYPDLISIKKNKTITKIRILSEKKQLIRLDFQEKYISKKFNLLYEKIISSLTYYKVLVLSDYAKGTLVNVKKIITLAKKMSIPILIDPKGLDFKKYSGATLLTPNLSEFEQIVGKCHQEKQILQRGIKLVSELNLSALLVTRSKNGMTLFQPEKQPIHFPALSKTASDVTGAGDTVISIIASSLATGYSLEEACFYANVGASIVIQKIGTETLTINQLNTVLNI
What are the official names of this protein?
Uncharacterized sugar kinase BUsg_057.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family.
Protein: YACG_SHIFL
Sequence: MSETITVNCPTCGKTVVWGEISPFRPFCSKRCQLIDLGEWAAEEKRIPSSGDLSESDDWSEEPKQ
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: RECA_STRP3
Sequence: MAKKLKKNEEITKKFGDERRKALDDALKNIEKDFGKGAVMRLGERAEQKVQVMSSGSLALDIALGAGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGIAAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVAALVPRAEIDGDIGDSHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGVMFGNPETTPGGRALKFYASVRLDVRGTTQIKGTGDQKDSSIGKETKIKVVKNKVAPPFKVAEVEIMYGEGISRTGELVKIASDLDIIQKAGAWFSYNGEKIGQGSENAKRYLADHPQLFDEIDRKVRVKFGLLEESEEESAMAVASEETDDLALDLDNGIEIED
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPAC_BACAC
Sequence: MEKVLVFGHKNPDTDAICSAIAYAELKKELGMNAEPVRLGEISGETQFALDYFKVEGPRFVETVANEVDNVILVDHNERQQSANDIESVRVLEVIDHHRIANFETSDPIYYRCEPVGCTATILNKMYKENGVTIRKEVAGLMLSAIISDSLLFKSPTCTEQDVAAARELAEIAGVDADKYGLEMLKAGADLSGKTMEQLISLDAKEFQMGNAKVEIAQVNAVDTNDVLVHQAELEKVISAVVEEKGLDLFLFVVTDILTNDSVGLAIGKAANIVEKAYNVSLENNTATLKGVVSRKKQIVPVLTEAFQA
What are the official names of this protein?
Probable manganese-dependent inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase class C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: K22O_MOUSE
Sequence: MSRQACKKSFSCGSQGFSGHSAVVSGSSRSSCVARSGAASGGACGFRSGAGSLGSHSLYSLGGSKSISISVAAGGSRAGGFSGGRSSCGSGFGSGYGGSLGGSRGMGAGFGGPSGFGGAGGFGRPGSFGPGSCPGGIQEVTINQSLLQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWELLQQQTIRSGSGPQNLEPFFESYISCLRKQLDSLLGAKGSLEGELKSMQDLVEDFKKKYEEEINRRTAAENEFVGLKKDVDGAFMNKVELQAKVDSLTDEINFLRTLYDMELSQIQSHVSDTSVVLSMDNNRCLDLDSIIAEVKAQYEDIAQKSKAEAEALYQTKLGELQTTAGRHGDDLRSTKSEIMDLNRMIQRLRAEIENVKKQNTNMQTSIAEAEQRGERALKDADTKFQDLQVALQKAKEDMARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLSGEFQNAVSISVVSNVTSTSSSGSFRGTGGSNYGGDSSGRSGGSSSSSSRGSSSRGSSGSRLGSGGSISVSQQRMGFNSGGSQTSVGSSYKSGRGGSSSVQFSQTTSSSQQRSK
What is the function of this protein?
Probably contributes to terminal cornification.
What are the official names of this protein?
Keratin, type II cytoskeletal 2 oral, Keratin-76, K76, Type-II keratin Kb9.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: ARFE_ORYSJ
Sequence: MASMKQQQTPASSAVTAAAAASSSATAAVAACEGERKAAAINSELWHACAGPLVSLPPVGSLVVYFPQGHSEQVAASMQKDVDAHVPSYPNLPSKLICLLHGVNLHADPDTDEVYAQMTLQPVNTYGKEALQISELALKQARPQMEFFCKTLTASDTSTHGGFSVPRRAAEKIFPPLDFSMQPPAQELQARDIHDNVWTFRHIYRGQPKRHLLTTGWSLFVSGKRLFAGDSVIVVRDEKHQLLLGIRRANRQPTNISSSVLSSDSMHIGVLAAAAHAAANSSPFTIFYNPRASPTEFVIPFAKYQKALYSNQISLGMRFRMMFETEELGTRRYMGTITGISDLDPVRWKNSQWRNLQVGWDESAAGERRNRVSIWEIEPVAAPFFLCPQPFFGVKRPRQLDDESEMENLFKRAMPWLGEEVCIKDTQNQNSTAPGLSLVQWMNMNRQQSSSLANTAAQSEYLQALGNPAMQNLAADELARQLYVQNNLLQQNCIQFNSPKLPQQMQTMNDLSKAAIPLNQLGAIINPQDQKQDAVNHQRQQNSIQVIPLSQAQSNLVQAQVIVQNQMQQQKPSPTQNPQRINGQRLLLSHQQKDQNLQLQQQLLLQQKQQLQQQQQQQQQNQQQLNKSLGQLVNLASQQSKLFDEELQLQILQKLQQQSLMSQSTSTLSQPPLIQEQQKLITDMQKQLSNSHSLAQQQMMPQQEIKPSLQATPLLPTVQQEQQQKLLQKQVSLADVSGVAFQPISSTNVIPKTGGAMIISGATQSVVTEEMPSCSTSPSTANGNHFTQSTKNRHCINTERLPPSTAPMLIPTSIDAVTATPLMTKELPKPNNNVKQSVVNSKLPNVAPGPQNCINHALQTDNLETSSSATSLCPSRTDGLVHQGFPSSNFNQHQMFKDALPDVEMEGVDPSNSGLFGINNDNLLGFPIETEDLLINALDSVKYQNHISTDVENNYPMQKDALQEISTSMVSQSFGQSDMAFNSIDSAINDGAFLNKNSWPAAPLLQRMRTFTKVYKRGAVGRSIDIGRYSGYEELKHALARMFGIEGQLEDRQRIGWKLVYKDHEDDILLLGDDPWEEFVNCVRCIRILSPQEVQQMSLDGDLGSNVLPNQACSSSDGVNGWRPRCDQNPGNPSIGPYDQFE
What is the function of this protein?
Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs).
What are the official names of this protein?
Auxin response factor 5.
What is the protein family that this protein belongs to?
Belongs to the ARF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: UBIA_ACTP2
Sequence: MTTFFQQHFSRNKWLAYAQLMRFDKPIGTLLLLHPTLWALFAAAGGMPPLSVLVIFVLGVIVMRAAGCVINDYADRHIDGEVKRTSQRPLATGRVTTTEAKILFVLLLCIAFVLDLLLNRYTFLLSFVAVALAIIYPFMKRFTHLPQVVLGMAFGWAIPMAYGAVSESLPLECWLLFFANIFWTVAYDTQYAMVDRDDDLRIGVKSTAILFAQYDNKIIALLQFITLVLLVIFGWISQYHWGYFVVLGLSASLFSHQCWLTKQRVREQCFKAFLNNHYFGLGVFFAILVGIYA
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PAIR3_ORYSJ
Sequence: MEVELTNIQKATSSDYWSLASNQYPCGKFPKVSVGVTIPRTSSVSRGRDAASTAAFEKNLSQGTDGRSRPPKMDNASLQVSPEAANHGGSAKEVPKPVPAKVSVSQPDDNAIEQTGTFSFGTRREQDSHLDQLDRPPLVSSQGKRQVESADKNKPNSEMLRMKLWEILGGTSQNKEAVASPNPEDIETPCQPKSQIANGPSSGRQKVFTSPVPYNIKTPAQFNSQTANKPSSDPIESDSDSPQVVEVRPITRSLGRKKEPTGSTHQDKSGSAKKPLSTHRSTPKQKILDNVFAFNDKCTPKTVGKSANGESGSLRNLRSLSRRAKVEPKKAHCSDRISHKTTQDDMERKVPSKYIPSEKKGEKTNSFSSLSRTGKTAESCSRSPKRERRVNTMANVGARKMQLSENLLVKTLNDGEHKLSSPQLTSFKSKGKCSSISPQQKENDNTHIPEASDRTAARNSFNSTPSPAANPSPVLRKYSWEHDENPAINGKSGQKDASPLADRFSDMPDDFASPTFAANIKISPHRSKMLDDDLFSSKYPKGVNRSRSTSFTSDPESEPLDKMEKTNELPGSESPNSQEERQNRKQPHLSPLSPIESEGAQISIPSFRKGYKSHKWLSDVDSPDKSSIEHLGRKSHLKEGRKGKRQLTSPTHFATSGTQETMSDKEPEKVPENYLTRAFDQLVVVLGRFQTKIKSETRNKSSKILAATGEIIRQHLEGVEGQMQADVDKLVNAGKSKRKRLESTFEEQQEKLRILHEKFKEEVNQQLLGCKNSVEDFEAYHAELKGVADKQKASHKKLLQNAEKTVGAQLSDAETKIAEVQKRARKRMKGLKFVLKELIAETAE
What is the function of this protein?
Plays a crucial role in homologous chromosome pairing and synapsis in meiosis.  Does not seem required for cytokinesis (PubMed:19392701).  Is essential for meiotic bouquet formation, homologous chromosome pairing and normal recombination, and synaptonemal complex (SC) assembly.  Required for the proper association of PAIR2 with chromosomes (PubMed:21119003).
What are the official names of this protein?
Meiosis-specific protein PAIR3, Protein HOMOLOGOUS PAIRING ABERRATION IN RICE MEIOSIS 3.
What are the subcellular locations of this protein?
Chromosome. Nucleus. Note=During interphase-early leptotene, distributed as numerous punctuate foci throughout the chromatin. Associates with chromosomal axes at leptotene, zygotene and pachytene (PubMed:21119003). Associates with chromosomal axes at zygotene (PubMed:27436711).
Protein: CATB2_ARATH
Sequence: MADNCIRLLHSASVFFCLGLLISSFNLLQGIAAENLSKQKLTSWILQNEIVKEVNENPNAGWKASFNDRFANATVAEFKRLLGVKPTPKTEFLGVPIVSHDISLKLPKEFDARTAWSQCTSIGRILDQGHCGSCWAFGAVESLSDRFCIKYNMNVSLSVNDLLACCGFLCGQGCNGGYPIAAWRYFKHHGVVTEECDPYFDNTGCSHPGCEPAYPTPKCARKCVSGNQLWRESKHYGVSAYKVRSHPDDIMAEVYKNGPVEVAFTVYEDFAHYKSGVYKHITGTNIGGHAVKLIGWGTSDDGEDYWLLANQWNRSWGDDGYFKIRRGTNECGIEHGVVAGLPSDRNVVKGITTSDDLLVSSF
What is the function of this protein?
Thiol protease that plays a central role in plant programmed cell death (PCD).  In addition to its role in protein degradation, may cleave and/or degrade a number of target proteins, activating signaling towards PCD.  Contributes to the increase of caspase-3-like activity after UV-C-induced PCD and is required for abiotic stress-induced PCD (PubMed:27058316).  Functions redundantly with CATHB1 and CATHB3 in basal defense and distinct forms of plant programmed cell death (PCD).  Participates in the establishment of basal resistance against the bacterial pathogen Pseudomonase syringae pv.  tomato DC3000.  Required for full levels of PCD during resistance (R) gene-mediated hypersensitive response (HR).  Involved in the regulation of senescence, a developmental form of PCD in plants (PubMed:19453434).
What are the official names of this protein?
Cathepsin B-like protease 2, Cathepsin B2, AtCathB2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Vacuole.
Protein: RL4_STRR6
Sequence: MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASLRQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLPQKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGNEFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.