PharMolix/UniProtQA huggingface dataset:
Protein: LASP1_BOVIN
Sequence: MNPNCARCCKIVYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGLECERRDPQESSYRRPQEQQQPHHIPASTPVYQQPQQQPAAQSYGGYKEPAAPASIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEAI
What is the function of this protein?
Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities.  Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity).
What are the official names of this protein?
LIM and SH3 domain protein 1, LASP-1.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Note=Associated with the F-actin rich cortical cytoskeleton.
Protein: CC191_MACFA
Sequence: MLMAPQGRSSSKKRMGLNRWKRFTRKPSPQHAFGPDNVEHWIKRVEKASEFAVSNAFFTRNSDLPRSPWGQITDWKTSEQIEDHDEIYAEAQELVNDWLDSKLKQELASDEEGDAKNTVSSVSLVPEANDHLKYDKFDDLCGYLEEEEESTTVQKFIDHLLHKNVVDSAVMEDLGRKENQDKKQQKDPRLTMEMRHKQVKENRLRREKELEYQRIQKTLKKSAFLEAQCLVQEEKKRKALEAKKEEEEIQREMVKLRREIIERRRTVKEAWKIEKKRQEENSQNSSEKLMFQSTHILLDEEKMAKERKRKLKELLIQIFKENQQCQKRYFSAWHKLILDHRIKLGKAGTLSDWKIQLKVLRAWRDYTRSQKLQRETQALENDLREENRKQQLAAEHNRKQVLRHCFTEWQHWCGAELLKRELALTKEENRKKMDALLKAASLGKLSASESSGISLPEEATAVVGPPVRNGQVTAVPPLWEKPPLGSSDCMLSPPLGRTTGNLQGSLQNVPLSAPGNKQHKTLGVEPPQLPGSNETLRTTSQKAEPLCLGHFHSRHVFQQQLIEKQKKKLQEQQKTILELKKNQRLAEAQWAAEHASAVTDTQSHLLSKPRGEEEPRTCQMLVNSPVASPGTEGSRSDSRNCLSGRKRKPKQLMTPHPILKAMEERAIQRAERRRILAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLEAIAKEHYEGVLLRKKGLEPWKILRMQSKQNVQVAEEHYCLFLQRKYLLTWFQCSQESLARKMAQADQFYSQILLKRVIRSWLQYMTDLQEEVRKFCVRFLQKKIFRAWFNMVREVKIDSRGKHEIAAEHSDRRILWITFRTWKKFVKFMKEERVKEERRQQLRRKVVEILPDFQVPGSDHELYQQSDTWSLSKTSLL
What are the official names of this protein?
Coiled-coil domain-containing protein 191.
Protein: PSRP_SHEPA
Sequence: MLRKVFYISDGTAITAEVFGHAVLSQFPLEFDALTIPFVETQEKAEAVKAQINDCFITTGERPLVFHSIVKAEIRDIIYSSEGLDYDFLNTFVAPLEKQLGVAAAPALHRTHGKANESYEARIDAINYAMENDDGQTMKHMDKADLILLGVSRCGKTPSSLYLSMQFGIKAANYPFTEDDMDNLKLPEALKRNKHKLFGLTIDPERLHEIRHSRMSNSRYSSLRQCRVEVKEVEMLYKKERIPYVNTTNHSVEEIATKILEETGLKRHMF
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: MLTF_METFK
Sequence: MRLLVIFLLALLLMACKEAPKPLADPRTTKEIIVVTHNGPSTYYYSGNNQYAGLEHDLVRNFVRELGPEYSVKFLVVNNISQVIPTLLKHKAHFAAADLSITRTREHLVRFTRPYQKVQQQIVFNNELTKAPKNIKELLNRQIAVPSGTSYSERLQRLKEQEPLLSWTETPHANSDELMAQVAEGELDFTVADGHLIALVQNYYPNLGATLALGKPEEIAWAFPKTGDTWLYEKANAFFTRISQDGTLNHLIDRYYGHADRLKPVDVTTFMQRSETLLPQYKRLFYEAQELTGLDWRLVAAIAYQESHWDRFNTSPTNVRGMMMLTEDTADRLGVTDRLDARQSIIAGARYVLMLKDLIPDSVHEPDRTWMALAAYNIGYAHLQDARILAKRLKLNPDRWVDVKKALPLLSKEEYFSTLKYGFARGGAPVVFVESVRTYHKILARREPRHTPIFPSFEVANLNGFGNTLSQE
What is the function of this protein?
Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product.  Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus.  Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase F, Murein lyase F.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane.
Protein: RHAA_SALPA
Sequence: MTTQLEQAWELAKQRFAAVGIDVEEALRQLDRLPVSMHCWQGDDVAGFENPEGSLTGGIQSTGNYPGKARNATELRADLEQALRLIPGPKRLNLHAIYLESDTPVARDQIKPEHFKNWVEWAKANRLGLDFNPTCFSHPLSADGFTLSHPDAKIRQFWIDHCKASRRVSAYFGEQLGTPSVMNIWIPDGMKDITVDRLAPRQRLLEALDEVISEKFDPAHHIDAVESKLFGIGAESYTVGSNEFYMGYATSRQTALCLDAGHFHPTEVISDKISAAMLYVPRLLLHVSRPVRWDSDHVVLLDDETQAIASEIVRHNLFDRVHIGLDFFDASINRVAAWVIGTRNMKKALLRALLEPTDQLRQLEASGDYTARLALLEEQKSLPWQAVWEMYCQRHDTPAGSQWLDSVRAYEKEILSKRS
What is the function of this protein?
Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
What are the official names of this protein?
L-rhamnose isomerase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURC_BURP6
Sequence: MKHIVKHIHFVGIGGAGMSGIAEVLVNLGYQVSGSDLARNAVTERLEALGARVSIGHDAANIEGANAVVVSTAVRSDNPEVLAARRLRVPIVPRAVMLAELMRLKQGIAIAGTHGKTTTTSLVASVLAAGGLDPTFVIGGRLTSAGANARLGTGDFIVAEADESDASFLNLYPVIEVITNIDADHMDTYGHDFARLKQAFIEFTQRLPFYGSAVVCIDDANVRQIVPLISKPVVRYGFAADAQVRAENVEARDGRMHFTVRREGREPLPVVLNLPGLHNVQNALAAIAIATDLDVADAAIQQALAEFNGVGRRFQRYGEIAAAGGGAYTLIDDYGHHPVEMAATIAAARGAFPGRRLVLAFQPHRYTRTRDCFDDFVNVLSTVDALVLTEVYAAGEAPISTANGDALSRALRAAGKVEPVFVATVDEVPDALAKLARDGDVVITMGAGSIGGVPGKLAQDTQQKG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_RUTMC
Sequence: MNIKQIKAREVLDSRGNPTVEVDVILDDDTIGSAMVPSGASTGQREALELRDGGTRYLGKGVLKAVEFVNTEICNTLINFGIEDLGKIDQAMIDLDGTETKSRLGANAILAVSLAVAHANANRQHKPLYMSLNQGENYKLPVPMMNIINGGEHANNNVDIQEFMIIPAGAPSFKEALRYGAEVFHHLKAVLEAKNMNTTVGDEGGFAPDLSSNEDAIKVILEAIDNAGYKAGKDIFIGIDAASSEFYENGTYNLVSENKSLNSEEFVDYLANWVENYPIISIEDGMDENDWNGWNLLTKKIGDKVQLVGDDLYVTNSKFLKQGIEKNITNSILIKVNQIGTLTETFQVMKMATDAGYTSVMSHRSGETEDTTIADLAVATGCGQIKTGSLSRSDRLAKYNRLLRIEEELGAKAVYPGLDAFNHLN
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RL28_HELHP
Sequence: MARKCFFTGKGPMVGNNVSHANNKTKKRSLPNLRSIRLKLEDGTSVRVKVAASTLRTIKKYS
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: MGAT1_HUMAN
Sequence: MLKKQSAGLVLWGAILFVAWNALLLLFFWTRPAPGRPPSVSALDGDPASLTREVIRLAQDAEVELERQRGLLQQIGDALSSQRGRVPTAAPPAQPRVPVTPAPAVIPILVIACDRSTVRRCLDKLLHYRPSAELFPIIVSQDCGHEETAQAIASYGSAVTHIRQPDLSSIAVPPDHRKFQGYYKIARHYRWALGQVFRQFRFPAAVVVEDDLEVAPDFFEYFRATYPLLKADPSLWCVSAWNDNGKEQMVDASRPELLYRTDFFPGLGWLLLAELWAELEPKWPKAFWDDWMRRPEQRQGRACIRPEISRTMTFGRKGVSHGQFFDQHLKFIKLNQQFVHFTQLDLSYLQREAYDRDFLARVYGAPQLQVEKVRTNDRKELGEVRVQYTGRDSFKAFAKALGVMDDLKSGVPRAGYRGIVTFQFRGRRVHLAPPLTWEGYDPSWN
What is the function of this protein?
Initiates complex N-linked carbohydrate formation.  Essential for the conversion of high-mannose to hybrid and complex N-glycans.
What are the official names of this protein?
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase, N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I, GNT-I, GlcNAc-T I.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 13 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein. Cytoplasm, perinuclear region. Note=Co-localizes with BRI3 isoform 1 at the perinuclear region.
Protein: MURG_STRT1
Sequence: MAKSKKIVFTGGGTVGHVTLNLILIPKFLKDGWEVHYIGDKHGVEHEQIDKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGILQSIAIIAKIRPQALFSKGGFVSVPPVIASKLLRVPVYVHESDLSMGLANKIAYKFATTMFTTFEQSKTLVKTRHVGAITKVGMTRFDNSDQLDKIKEQFDEKLKTVLFIGGSAGAKVFNDFISKTPELIENYNIINISGDSSLNTLERHLYRVDYVTDLYQPLMDMADLVVTRGGSNTIFELLAMKKLHLIVPLGKEASRGDQLENADYFERKGYARQLQEPELSWETLKHELEQLVEHAETYKEAMAKSEEITSPDDFYNLLVTSISNK
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y1015_BURTA
Sequence: MAGHSKWANIKHKKAAADAKRGKIWTRLIKEIQVAARLGGGDANSNPRLRLAVDKAADANMPKDNVKRAIDRGVGGADGANYEEIRYEGYGIGGAAIIVDTLTDNRTRTVAEVRHAFSKFGGNMGTDGSVAFMFDHVGQFLFAPGTSEDALMEAALEAGANDVNTNDDGSIEVLCDWQEFSKVKDALEAGGFKAELAEVTMKPQNEIEFTGEDAVKMQKLLDALENLDDVQDVYTNAVVIEE
What are the official names of this protein?
Probable transcriptional regulatory protein BTH_I1015.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RM20_HUMAN
Sequence: MVFLTAQLWLRNRVTDRYFRIQEVLKHARHFRGRKNRCYRLAVRTVIRAFVKCTKARYLKKKNMRTLWINRITAASQEHGLKYPALIGNLVKCQVELNRKVLADLAIYEPKTFKSLAALASRRRHEGFAAALGDGKEPEGIFSRVVQYH
What are the official names of this protein?
39S ribosomal protein L20, mitochondrial, L20mt, MRP-L20, Mitochondrial large ribosomal subunit protein bL20m.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: HIS1_LEPIN
Sequence: MLTLALPKGRLAEESIDLMISKGWLSSKPDPNSKELIYNDPKGKIRILLVRSQDVATYVEQCAADAGISGWDVLKEGGYDLATPLDLKIGKCRLSLAAPNGFTLEAHHRKIRVATKYPNLAREFFFLKGLSCEIFKLYGSIELAPLVGLSDCIVDLVSTGGTLKANGLKELDIILESSARLVFNRSSLYGKRKEAVEFMDSLSKI
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRP75_CRIGR
Sequence: MISATRAAAARLVGTAASRTPAAARHQDGWNGLSHEAFRFVSRRDYASETIKGAVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTNPNNTFYATKRLIGRRYDDPEVQKDTKNVPFKIVRASNGDAWVEAHGKLYSPSQIGAFVLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALAYGLDKSEDKIIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQALLRHIVKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDASGPKHLNMKLTRAQFEGIVTDLIKRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDLFGRAPSKAVNPDEAVAIGAAIQGGVLAGDVTDVLLLDVTPLSLGIETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIEVTFDLDANGIVHVSAKDKGTGREQQIVIQSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAVNMAEGIIHDTETKMEEFKDQLPADECNKLKEEISKMRELLARKDSETGENIRQAASSLQQASLKLFEMAYKKMASEREGSGSSGTGEQKEDQKEEKQ
What is the function of this protein?
Chaperone protein which plays an important role in mitochondrial iron-sulfur cluster (ISC) biogenesis.  Interacts with and stabilizes ISC cluster assembly proteins FXN, NFU1, NFS1 and ISCU.  Regulates erythropoiesis via stabilization of ISC assembly.  May play a role in the control of cell proliferation and cellular aging.
What are the official names of this protein?
Stress-70 protein, mitochondrial, 75 kDa glucose-regulated protein, GRP-75, Heat shock 70 kDa protein 9.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Mitochondrion. Nucleus, nucleolus.
Protein: RMT2_KLULA
Sequence: MSDLHHLLTFPERPISESSYLPELTRLLSAGIPATYTLEQAAAFERGEEVTEEDSNTTPLHILCRSLPSFEGSSKLSEDEESVVLKLMDTLLEYGAGWNFLDYENKHIGDLVLERKYPQDHCIYQRIVDAGVSAELLLRKIDGGEIEFIEDPEDAATEAATEAATEAEVIEGVTKGSEEAPFEDATAADQATYLKTDLEYTDDALVTKENRDGVMMDWETDIMSMAAKSLVSTRSTDECVVLNIGFGMGIIDNFIQDEKVTKHYICEAHPDVLAKMKETGWFDKENVVILEGRWQSRLNELLDQGEVFFDGIYYDTFSEHYQDMLDLYDVIVGLLKPEGTFSFFNGLGADRPVCYDVYRKIVELDVANYGMECRYQVINLRTLPNWNDVKRSYFNCTYYYHPEIRFA
What is the function of this protein?
S-adenosyl-L-methionine-dependent protein-arginine N-methyltransferase that methylates the delta-nitrogen atom of arginine residues to form N5-methylarginine (type IV) in target proteins.  Monomethylates ribosomal protein L12.
What are the official names of this protein?
Protein arginine N-methyltransferase 2, Protein-arginine N5-methyltransferase, Type IV protein arginine N-methyltransferase, Type IV PRMT.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CLPX_BRUC2
Sequence: MSKVSNGGGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSMVKSREGVPTPQEIMAVLDDYVIGQKDAKRVLSVAVHNHYKRLAHQSKNSDIELAKSNILLVGPTGCGKTYLAQTLARIIDVPFIMADATTLTEAGYVGEDVENIILKLLQAADYNVERAQRGIVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTNILFICGGAFASLDRIISARGEKTSIGFGATVKSVDERRIGEVFKELEPEDLLKFGLIPEFVGRLPVIATLEDLDVDALVQILTEPKNALVKQYQRLFDMENVELVFHDDALRAIANKVVEHKTGARGLRSIMEKILLDTMFELPTLEGVREVVISGDVVDGSARPLYIYAERQDEKGNVSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: GLPE_YERPP
Sequence: MEQFEAISVEQAYLRWKEGKTALVDIRDPQSYEAGHAPGAFHLTNSSLHTFMQQTDFDQPVMVMCYHGNSSKGAAQYLLQQGFDVVYSIDGGFEAWARSYPQDITSESR
What is the function of this protein?
Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
What are the official names of this protein?
Thiosulfate sulfurtransferase GlpE.
What is the protein family that this protein belongs to?
Belongs to the GlpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERA_LACPL
Sequence: MAEQQAFHSGFVAIIGRPNVGKSTLLNRVVGQKVAIMSDKAQTTRNRIQGIYTTADTQMVFIDTPGIHKPHSRLGDFMVKSALSTLGEVDAVLFMINADERRGAGDNFIIDRLKTVKQPIYLVINKIDQVHPDHLLEIMDQYKDALPWKEVYPISALEGNNVDELLTTLKGQLPEGPQYYPSDQITDHPERFIISELIREKVLELTRQEVPHSTAVVIDSIKRQDEEKIHVQATIIIERSSQKGIIIGKGGSMLKKIGSLARRDIEHLLGDKVYLELWVKVQENWKDRQDLLASYGYRQDDY
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: QUEC_LEGPL
Sequence: MKKAVVLLSGGLDSTTCLALAKSQGFACYALSFSYGQRHSAELCAATRIAKHMGAADHKIVTLDIALFGGSALTDASIEVPEFKESPEIPVTYVPARNTIFLAMALGYAESIGARDIFIGASSVDYSHYPDCRPEFIESFQSLANLATKAGIEGDRFTINAPLQYLSKVQTIQLGAELGVDYGLTVSCYQANEAGEACGQCDSCTFRKRGFKSAGVDDPTRYQKCVHI
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: IMPCT_DICDI
Sequence: MNEEQENEILAISSIYPDSFSEIETIVGEEENDGFEDNDSQYSKIYQVIITPNISCLDENSLEDNNNSNNNNNNNNNNNNNGLIIDTSYDYLIYFKFKYTKEYPSNEPPIISIKATWLQKSDQSILLSHLEDLWNQNELVIFQMISWLQEESIEILNNHYKSIKKFSHYHLKKSLNTQQLNQNQNQFENQNQNQNQNQNQNQNKEKEKEKVPTIYTGQSVTEKKSKFQAHLAIVHSEREVQLVLNQLLSFKKIYEATHNMYAYRFQLENGEINEYYNDDGEDGAGDKMLFTLSKNQAKEILIVCTRWFGGILLGGRRYVHIVNTTKDILNLYNTNSLSQCSLEFN
What is the function of this protein?
Translational regulator that ensures constant high levels of translation under amino acid starvation.  Plays a role as a negative regulator of the EIF2AK4/GCN2 kinase activity; impairs GCN1-mediated EIF2AK4/GCN2 activation, and hence EIF2AK4/GCN2-mediated eIF-2-alpha phosphorylation and subsequent down-regulation of protein synthesis.
What are the official names of this protein?
Protein IMPACT homolog.
What is the protein family that this protein belongs to?
Belongs to the IMPACT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2007_ROSCS
Sequence: MTGRRTRLGDWGETMAARFLARRGYEVLARKWRCAAGEIDIVARHDGDLVFVEVRTRRGRDPGMAAESITNAKRARLMALADAFLAAHDLPSNTPWRIDVVAISVGLRAQEVSIEHIPYAVEEA
What are the official names of this protein?
UPF0102 protein Rcas_2007.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: TIM16_NEUCR
Sequence: MAYRLITQVVVVGSRVLGRAFAEAYKQAAASSQYQRAQQKNGNAATGRASLTSGMTLDEACKILNVNKPADGTAANMEEVMERFKRLFDANDPEKGGSFYLQSKVVRARERLEAEIKPKMEEKQAEEEVKEGWNPKIYKDR
What is the function of this protein?
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.  In the complex, it is required to regulate activity of mtHSP70 (hsp70-5) via its interaction with tim14/pam18.  May act by positioning tim14/pam18 in juxtaposition to mtHSP70 at the translocon to maximize ATPase stimulation (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit tim16, Presequence translocated-associated motor subunit pam16.
What is the protein family that this protein belongs to?
Belongs to the TIM16/PAM16 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein.
Protein: PSBN_STAPU
Sequence: METATLVVIFISCLLVSFTGYALYTAFGQPSKELRDPFEEHED
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: YT43_CAEEL
Sequence: MNEDNHESSSSGCDNQIEFLVSEAEQRRRRVNHLDTEVHGLGYDPFSYCGRRVHVLLLTKLISVLTIPFYVAIIIFISFFGNATSVMFSVIILGSVLISTCYGAFRGAKMCLIPFVIIQLVFLIYDLILITILLLAVVFPKMFLSALLRLPLEDIPFGTDQVLLGCSLLLALLLAPLVWTTHVVYIDFLFISQVDETLHMLKEANQKVSQDDVSPNRMMF
What are the official names of this protein?
Uncharacterized protein B0416.3.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HIUH_DANRE
Sequence: MNRLQHIRGHIVSADKHINMSATLLSPLSTHVLNIAQGVPGANMTIVLHRLDPVSSAWNILTTGITNDDGRCPGLITKENFIAGVYKMRFETGKYWDALGETCFYPYVEIVFTITNTSQHYHVPLLLSRFSYSTYRGS
What is the function of this protein?
Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
What are the official names of this protein?
5-hydroxyisourate hydrolase, HIU hydrolase, HIUHase, Transthyretin-related protein.
What is the protein family that this protein belongs to?
Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
What are the subcellular locations of this protein?
Peroxisome.
Protein: COAE_NEIMA
Sequence: MTVWVGLTGGIGSGKSAAAQCFADLGVPRIDADAAAHSLTASDGIALPEIRRLFGDTVFDTQGLLRRDILRKEVFASPSRKALLESVMLPLIFSEIKKQQETFTDAAYGIVEIPLLTEKRQFISLIRRVLTISAPLEKRIGRVMARSGLTRGEVAAVISHQASESERLLLADDVLLNDGSLKSLREKTMRLHAFYSGIFASKPTQGKHNG
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABZ_RHIWR
Sequence: MSEDAPKILGPLDVRRVMAALPHRYPLLLVDRVEELVVDERITAIKAVTINENFFQGHFPGRPIMPGVLIVEAMAQAAGVLAVESLGLAGSGKLVYFMTIDEVKFRTPVEPGVLLRLEVAFAQKRGSVCKFEGKAYIGDKLAAQANFTAMIADPPTD
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_STRPQ
Sequence: MANAIIETAKERFAQSHQSLSREYASIRAGRANASLLDRIQVDYYGAPTPLNQLASITVPEARVLLISPFDKSSIKDIERALNASDLGITPANDGSVIRLVIPALTEETRKELAKEVKKVGENAKIAIRNIRRDAMDDAKKQEKAKEITEDELKTLEKDIQKATDDAIKEIDRMTAEKEKELLSV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_ROSCS
Sequence: MARGNGIERVVADNRKARHDYFIEETYEAGVVLTGSEIKSIRAGQVNLRGGYVRIVNGEAWLYDVHIAPYEQSGKYFNHEPTRPRKLLLHRREISRIAGQVERQGYTLVPLRLYLRGSRAKVEIGLARGKKLYDKREDIARREARRTIDRALKERARH
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.