PharMolix/UniProtQA huggingface dataset:
Protein: SYP52_ARATH
Sequence: MASSSDPWMREYNEALKLSEDINGMMSERNASGLTGPDAQRRASAIRRKITILGTRLDSLQSLLVKVPGKQHVSEKEMNRRKDMVGNLRSKTNQVASALNMSNFANRDSLFGTDLKPDDAINRVSGMDNQGIVVFQRQVMREQDEGLEKLEETVMSTKHIALAVNEELTLQTRLIDDLDYDVDITDSRLRRVQKSLALMNKSMKSGCSCMSMLLSVLGIVGLALVIWLLVKYL
What is the function of this protein?
Vesicle trafficking protein that functions in the secretory pathway.
What are the official names of this protein?
Syntaxin-52, AtSYP52.
What is the protein family that this protein belongs to?
Belongs to the syntaxin family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Single-pass type IV membrane protein. Prevacuolar compartment membrane; Single-pass type IV membrane protein.
Protein: CCR5_CANLF
Sequence: MNYQTSTPYYDIDYGTSEPCQKVNVRQIAARLLPPLYSLVFIFGFVGNVLVVLILIDCKKLKSMTDIYLLNLAISDLLFLLTIPFWAHYAADQWTFGNKMCQLLTGLYYIGFFTGNFFIILLTMDRYLAIVHAVSASKARTVTFGVVTSGIAWVVAVLASFPRIIFTRSQKEGSRFTCSPHFPPSQHHFWKNFQALKMSVLGLILPLLVMIIGYSAILKTLLRCRNEKKRHKAERLIFVIMIVYFLFWAPYNIVLLLSTFQEFFGLNNCNSSNRLDQAMQITETLGMTHCCINPIIYAFVGEKFRRYLSLFFRKHIARRFCKCCPIFQGELPDRVSSVYTRSTGEQEISVAL
What is the function of this protein?
Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level.  May play a role in the control of granulocytic lineage proliferation or differentiation (PubMed:16806494).  Participates in T-lymphocyte migration to the infection site by acting as a chemotactic receptor (By similarity) (PubMed:16806494).
What are the official names of this protein?
C-C chemokine receptor type 5, C-C CKR-5, CC-CKR-5, CCR-5, CCR5.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: T1S2_METJA
Sequence: MVIIMQFYKEENFKEMHGLRVPEDWEVVRIGDFIKYIKGKKPAVMVDEELEGYYPYLSTEYLRDGIASKFVKITNKEIIVNENDILLLWDGSNAGEIFLGKKGILSSTMVKLEQKNKIMDDLYLFYSLKLKESFLKSQTKGTGIPHVDKKIFENIKIPLPPLEEQKQIAKILSDFDNLIGTINKQIEVLNKAKKGMMKKLFTKGVFEHKSFKKSEIGEIPEDWEVVKLKEVVDIQSGKYFKYSEFCENGVKCLKIDNVGFGKIFWETVSFLPEDYLNKYPQLVLKSGDIVLALNRPIIGGKIKIGILKDIDEPAILYQRVGRFIFKSEKIDKQFLFYLLMSEYFKKELSKLLIGTDQPYIRTPVLLNIKIPLPHLEEQKAMAERLKSIDNLIEIKRKEKEQIEKAKKKIMNLLLTGKIRVKNLNF
What is the function of this protein?
The specificity (S) subunit of a type I restriction enzyme; this subunit dictates DNA sequence specificity.  The M and S subunits together form a methyltransferase (MTase) that methylates A-2 on the top and A-3 on the bottom strand of the sequence 5'-GAYN(5)GTAA-3'.  In the presence of the R subunit the complex can also act as an endonuclease, binding to the same target sequence but cutting the DNA some distance from this site.  Whether the DNA is cut or modified depends on the methylation state of the target sequence.  When the target site is unmodified, the DNA is cut.  When the target site is hemimethylated, the complex acts as a maintenance MTase modifying the DNA so that both strands become methylated.  After locating a non-methylated recognition site, the enzyme complex serves as a molecular motor that translocates DNA in an ATP-dependent manner until a collision occurs that triggers cleavage.
What are the official names of this protein?
Type I restriction enzyme MjaVIII specificity subunit, S protein, Type I specificity subunit S.MjaVIII, S.MjaVIII.
What is the protein family that this protein belongs to?
Belongs to the type-I restriction system S methylase family.
Protein: NU4LC_HUPLU
Sequence: MFGHALLLGAFPFCIGIYGLITSRNTVRALMCLELIFNAVNVNFVTFPNYLDIQQIKGEILSVFVIAVAAAEAAIGSAIVLAIYRNRESIRIDQFNLLKW
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic, NAD(P)H dehydrogenase subunit 4L, NADH-plastoquinone oxidoreductase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: TAT_HV1AN
Sequence: MDPVDPEVPPWHHPGSQPQIPCNNCYCKRCCYHCYVCFVRKGLGISYGRKKRGRPAAASHPDHKDPVPKQSPTITKRKQERQEEQEEEVEKKAGPGGYPRRKGSCHCCTRTSEQ
What is the function of this protein?
Extracellular circulating Tat can be endocytosed by surrounding uninfected cells via the binding to several surface receptors such as CD26, CXCR4, heparan sulfate proteoglycans (HSPG) or LDLR.  Neurons are rarely infected, but they internalize Tat via their LDLR.  Through its interaction with nuclear HATs, Tat is potentially able to control the acetylation-dependent cellular gene expression.  Modulates the expression of many cellular genes involved in cell survival, proliferation or in coding for cytokines or cytokine receptors.  Tat plays a role in T-cell and neurons apoptosis.  Tat induced neurotoxicity and apoptosis probably contribute to neuroAIDS.  Circulating Tat also acts as a chemokine-like and/or growth factor-like molecule that binds to specific receptors on the surface of the cells, affecting many cellular pathways.  In the vascular system, Tat binds to ITGAV/ITGB3 and ITGA5/ITGB1 integrins dimers at the surface of endothelial cells and competes with bFGF for heparin-binding sites, leading to an excess of soluble bFGF.
What are the official names of this protein?
Protein Tat, Transactivating regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the lentiviruses Tat family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Secreted. Note=Probably localizes to both nuclear and nucleolar compartments. Nuclear localization is mediated through the interaction of the nuclear localization signal with importin KPNB1. Secretion occurs through a Golgi-independent pathway. Tat is released from infected cells to the extracellular space where it remains associated to the cell membrane, or is secreted into the cerebrospinal fluid and sera. Extracellular Tat can be endocytosed by surrounding uninfected cells via binding to several receptors depending on the cell type.
Protein: FLAB1_METVO
Sequence: MNIKEFLSNKKGASGIGTLIVFIAMVLVAAVAASVLINTSGFLQQKASTTGKESTEQVASGLQVTGVTGVNSTDSENITHIVAYITPKAGSSAIDLSQAKLFVTYNGVSAVLKANESAIDGTSGTPDVLSATLLSNTSATEYQVVSLQDFDGSVAKNQVINKGDLVAIRISTGQVFSSTKGIPTRAHVSGKLQPEFGAPGIIEFTTPATFTTKVVELQ
What is the function of this protein?
Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.
What are the official names of this protein?
Flagellin B1.
What is the protein family that this protein belongs to?
Belongs to the archaeal flagellin family.
What are the subcellular locations of this protein?
Archaeal flagellum.
Protein: MNTR_BACCQ
Sequence: MPTPSMEDYIEQIYLLIDEKGYARVSDIAEALSVHPSSVTKMVQKLDKDEYLIYEKYRGLVLTSKGKKIGERLVYRHELLEQFMRIIGVDESKIYNDVEGIEHHLSWEAIDRIGDLVQYFEQDEVRVETLRGVQKANEEKSN
What is the function of this protein?
Central regulator of manganese homeostasis.
What are the official names of this protein?
HTH-type transcriptional regulator MntR, Manganese transport regulator.
What is the protein family that this protein belongs to?
Belongs to the DtxR/MntR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDGC_PSEU2
Sequence: MWFKNLLVYRLTQDVPFDAEALETALATKPARACASQEVATYGFVAPFGKGEDAPLVHISQDFMLIAARKEERILPGSVVRDALKEKVDEIEAEQMRKVYKKERDQLKDEIIQAFLPRAFIRRSATFAAIAPKQGLILVNASSPKRAEDLLSTLREVIGSLPVRPLTVKVSPSATMTDWVKTQKAADNFFVLDECELRDTHEDGGIVRCKRQDLTGDEIQLHLSTGKVVTQLSLAWQDKLSFVLDDKLVVKRLKFEDLLQDQAEQDGGDEALGQLDASFTLMMLTFGEFLPELFEALGGEEIPQGI
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: OPPB_LACLS
Sequence: MWKVIIRRILLMIPQLFILSILVFFFAKLMPGDPFSGLIGPHTDPHEVEALRRAAGLYDPWWEQYLRWLGNAIHGNLGMSYNLKEPVMTVIGHRAINTFWMSLLSVILTYLFAIPMSIVAARNEGKWQDQLWLTYNSITFGIPPYVFYLLIIFIFGYSLNWFPTGGTVSPDAMGIIPVFFSKIYHMILPAFSLAVFGTVGIFTYFRSGILDEQTQDYVRTARAKGVKEKVIFRRHILRNASLPIASNFGFVITGLLGGAIFAETIFGYPGLGQLFITSISGRDYSMITALILLNGFLGLLGALLSDIIMAMVDPRIRIQ
What is the function of this protein?
Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Oligopeptide transport system permease protein OppB.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HLDE_PSEA8
Sequence: MKLSMPRFDQAPVLVVGDVMLDRYWHGATSRISPEAPVPVVRVEQHEDRPGGAANVALNIAALGAQALLVGVTGRDEAADSLANSLKAAGVDARFQRIDSQPTIVKLRVMSRHQQLLRVDFEEPFRTDAAALAVDVESLLAKVKVLVLSDYGKGALQNHQVLIQAARARNIPVLADPKGKDFAIYRGASLITPNLSEFETIVGRCADEAELVAKGQALMSELDLGALLVTRGEHGMTLLRDGQPALHLPARAREVFDVTGAGDTVISTLAAALAAGEELPSAVGLANLAAGIVVGKLGTAAISAPELRRAVQREQGSERGVLGLEQLLLAIEDARAHGEKIVFTNGCFDILHAGHVTYLEQARAQGDRLIVGVNDDASVTRLKGVGRPINSVDRRMAVLAGLGAVDWVVSFAEDTPERLLEQVRPDVLVKGGDYGVEQVVGAQIVKAYGGEVRVLGLVENSSTTAIVEKIRQR
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: SPZ9_ORYSJ
Sequence: MQVSSYLRRALRRPPFPAGDANHRRLSSAPAPKPEAPAEAMPPPPMPTRPWGEALAAAQRAFCLPLAGRVLAAAGTGNAAVSAPAVHVSLALAAGGARGATRRQVLQALGCGGGGRGGAADAANVASRVVKRVLRDRSTSGGPRLAFAGGVWADASRSLSPEFVGLAGNVYGSAAKKADFKNKPEDAPDQINSWVKDSTKGTVTTLLPAGTIDQNTGLVLGSALYFRGRWLDRDDLRRTTEQKFYCLDGTSVEVPFVEYDRTRLFAVHDNFKVIKLPYKQGKNERKFSMYIFLPDDHDGLFELTQKIFSEPMFLEQHLPTEKCHVGISVPNFKISFQIDVKDFLKDMGLELPFLREAEFSDMIKEDDSSGPLFLSDVLHKAVLEVDQKGIEETSVSMGLGKPLPAQHFKADHPFFFMIREEVSGTVIFMGHVLDPSSRT
What are the official names of this protein?
Probable non-inhibitory serpin-Z9, OrysaZ9.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
Protein: DEF2_VICFA
Sequence: LLGRCKVKSNRFNGPCLTDTHCSTVCRGEGYKGGDCHGLRRRCMCLC
What is the function of this protein?
Fabatins have antibacterial activity against Gram-positive and Gram-negative bacteria.  High activity against P. aeruginosa.  No activity against S. cerevisiae and C. albicans.
What are the official names of this protein?
Defensin-like protein 2, Fabatin-2.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
Protein: PSD_POLSJ
Sequence: MSHRFSVLPQYLLPKQALTAFAGFVASRERGWITTEIIRRFVAKYQVNMEEAARSDIASYLTFNDFFTRALKPGVRPLADADLISPVDGAISQFGRIEHDQIFQAKGHHYSTTALVGGDAALAAQFQNGSFATLYLSPKDYHRIHMPCDGRLARMVHVPGELFSVNPVTARGVPGLFARNERVVCVFDSPRGPFVLILVGATIVGSMATVWHGVVNPPRGKQVRAWDYDPNAEAAVVLRRGEEMGRFLLGSTVVMLFPAGPLHFNPDWAPGRLIRLGEAMANYA
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ISPD_PECCP
Sequence: MQTPSLSPPDIVAVLPAAGNGSRMQNDRPKQYLTIGNDATGHKTILEHTIDALLRHSRVRRVVVVISPDDAFFHTLAIASDPRICTVTGGRQRADSVLAGLSAVADGAWALVHDAARPCLHQDDLTRLLAIVEQSDVGGILAAPVRDTMKRSTDGFIDRTVERNDLWHALTPQLFPAALLKQCLQRALQDGVAVTDEASALEYCGYRPQIISGRADNIKVTRPEDLALAEFYLTSLQ
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: REG5_DROME
Sequence: MTTAAKVILACCLLGAFHIQISSSSAIPIWEFLTRNEKMSHLYSTFAQLVSVHCKSTAAVGGLPVNQCKHNLLGYGSAKLQTLSDVQLEALDPYQRDANELIWSSIMGDHPSGASLVTTRQPLQQPLPTPPASSLIILTRQQLPHGASHAHPIQSSGSATNPIFESGEQKHKYAMDMDKAYGYGPQSSSELPMAAALTSEPSKRFLTGPLVIRVRPDGSPVEEDKMMPLPRDEDLPYFHLGLAAAQPNRHRKIATISSLKQQHFASILQSDLQPPHQTQRRLFRQQQA
What is the function of this protein?
Involved in the generation of biological rhythms (Potential).  In the head, oscillates in abundance with a daily peak during early night, even under constant darkness.  Oscillation is dependent on period (per) function.
What are the official names of this protein?
Rhythmically expressed gene 5 protein, dReg-5.
Protein: HIS3_METM7
Sequence: MDLDTKEIIKNMDLKFRNIDGKKLLLAISTDKDRNILMTAFMNEESLEKSIETGFMHYYSTSRNKLWRKGEESGNVQKIIDVFRDCDGDALLFTVEQTGWACHEGYMSCFHNKIDLNTGKFTVVGNKLD
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: O3619_CONVE
Sequence: MSGLGIMVLTLLLLVSMATSHQDGGGKQATQRDAINVRRRRSITRRVVTEACEEYCEDRDKKTCCGLENGEPFCATLCFG
What are the official names of this protein?
Conotoxin VnMSGL-0121.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O3 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: IML2_ASPFU
Sequence: MFRVGSWLYGKKPAANASTQSLDSLVELRDLEDAMRAATLILNDDVDGAEAGLAEGTSAFHNLGRGVVAFIRATLGFEQDIMRQASERLNEAETSASVDQHRAQHNSYAPNTYHSPMYLPGTEFALCQAIAQLMSAIVGVLNESLTESIKAFYRLRKAYITLDAILKMEQKYMEESRAATLVESTTSGSVPSSLRHSSSNLHSSSSSISSAKGKEAAADTLAAPSNDTDVQERLADLNLSGEPAVAEDPGQTPTPINTDILDHDPDSDIFQNQIDVFVHSGSNFCFGVLLLLISMVPPSFSKLLSIIGFHGDKERGLKMLWQASKFHNLIGGIAAFAILGYYNGFVRYCDIMPDSIPGKDGDVQGYPQKRLELLLAKMRERFPKSQLWLLEESRMSGANKNLDRALELLCGEERSPLKQVEALRVFERSLNAMYLHKYELCADSFLECVDLNSWSRSLYYYIAGSCHLSLYRDAKETDSAKAAKHAELAEKYFRMAPTVAGKKRFMARQLPFDVFVARKFAKWEARAKEWKVSLVDAVGVDPIEEMIFFWNGHSRMTDEQLQESLQKLAWSESSANTTWSREGPEEKAILKLLRAAVHRSLRKHTQAKEMLEDILGQDRTLFKGHLKDDWICPVAHFEMAANLWMERPTYIATHGGAKQDSNKESARPASVNDALQYEREKVRKCKEYLEKAAKWESYELDARIGLKVTAAMEAVQKWESTHPTL
What is the function of this protein?
Inclusion body (IB) resident protein that interacts strongly with lipid droplet (LD) proteins.  Involved in LD-mediated IB clearing after protein folding stress, probably by enabling access to the IBs of an LD-stored soluble sterol derivative that acts as chaperone in inclusion clearing.
What are the official names of this protein?
Inclusion body clearance protein iml2.
What is the protein family that this protein belongs to?
Belongs to the IML2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localized exclusively in cytoplasmic inclusion bodies under protein folding stress conditions.
Protein: RT12_DICDI
Sequence: MITINQITDRKARGPKKKRKTLLTGYPQKKGYCMRVYETKPKKPNSAIRKVAKVTIKLKNKRKNLIAYIPGFGPHNLQPLSTVLVKGGRCQDLPGVKYRLVRKHYDFLAAERFVRKNRRSKFSVKNLETKAKKGKAVRIE
What are the official names of this protein?
Ribosomal protein S12, mitochondrial, MRP-S12, S12mt.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ADSL2_ARATH
Sequence: MSETTKDDGSSQKKSVRKEKRAYVLRKWTQFDVGRASTVGTVHLLCLLAPFNYKWEAFRFGIILAILTNLCITFSYHRNLTHRSFKLPKWLEYPFAYSALLALQGDPLDWVSIHRFHHQFTDSDRDPHSPIEGFWFSHVLWIFDTDYIREKCGRRNNVMDLKQQWFYRFLKKTLVLHILAFWTLIYLWGGLPYLTWTVGFGGVIGYHGTWLVNSACHICGSQAWQTNDTSRNVWWLALLTMGESWHNNHHAFETSARHGLEWYQLDITWYLIWFFQALGLATNVKLPTDAQKRKMAIRR
What are the official names of this protein?
Delta-9 desaturase-like 2 protein.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: GCST_YERP3
Sequence: MAKQTPLYDQHVACGARMVDFHGWMMPLHYGSQIDEHHLVRQDAGMFDVSHMTIVDLHGNRTREFLRYLLANDVAKLTQPGKALYTGMLNESGGVIDDLIVYFLSEDYFRLVVNSATRDKDLAWISQHAEPYQVEVTVRDDLALIAVQGPQAQQKVATLLTTEQQQAIAGMKPFFGIQTGDLFIATTGYTGEAGYEIALPKQQVVAFWQQLLAAGVKPAGLGARDTLRLEAGMNLYGQEMDEKTSPLAANMGWTVAWQPEDRQFIGRAALERQRMKGTEQLVGLIMTEKGVLRNELPVYFFDAAGNQHVGVITSGSFSPTLGFSIALARVPAGIGEHAVVQIRNREMPVRVTKPGFVRAGKAIVL
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: RL10E_NANEQ
Sequence: MARLRRWHCYRKLEVPYTRVSRSKNKNYIPGAKPTMVRLFHMGELTRNPSEWQYEASLVAKENHQIRDNAIEAIRVMVNKYLESTLGKKRYLFIIRKYPHHIYREKPVVGGYAGADRISQGMRLSFGRPKGRAVQIYEGEKLLSIFFDDITKAKDIKYFLQVARSKLPWRYREEIVEVKSGKPLAL
What are the official names of this protein?
50S ribosomal protein L10e.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: RD19B_ARATH
Sequence: MDYHLRVLFSVSLIFVFVSVSVCGDEDVLIRQVVDETEPKVLSSEDHFTLFKKKFGKVYGSIEEHYYRFSVFKANLLRAMRHQKMDPSARHGVTQFSDLTRSEFRRKHLGVKGGFKLPKDANQAPILPTQNLPEEFDWRDRGAVTPVKNQGSCGSCWSFSTTGALEGAHFLATGKLVSLSEQQLVDCDHECDPEEEGSCDSGCNGGLMNSAFEYTLKTGGLMREKDYPYTGTDGGSCKLDRSKIVASVSNFSVVSINEDQIAANLIKNGPLAVAINAAYMQTYIGGVSCPYICSRRLNHGVLLVGYGSAGFSQARLKEKPYWIIKNSWGESWGENGFYKICKGRNICGVDSLVSTVAATTS
What is the function of this protein?
Probable thiol protease.
What are the official names of this protein?
Probable cysteine protease RD19B, RD19-like protein 1, Thiol protease A1494.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Lytic vacuole. Note=Predominantly vacuolar. From the Golgi apparatus, probably transported to the lytic vacuole (LV) in clathrin-coated vesicles (CCVs) via the prevacuolar compartment (PVC).
Protein: YQAE_ECOL6
Sequence: MGFWRIVITIILPPLGVLLGKGFGWAFIINILLTLLGYIPGLIHAFWVQTRD
What are the official names of this protein?
UPF0057 membrane protein YqaE.
What is the protein family that this protein belongs to?
Belongs to the UPF0057 (PMP3) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SEM4C_MOUSE
Sequence: MAPHWAVWLLAAGLWGLGIGAEMWWNLVPRKTVSSGELVTVVRRFSQTGIQDFLTLTLTEHSGLLYVGAREALFAFSVEALELQGAISWEAPAEKKIECTQKGKSNQTECFNFIRFLQPYNSSHLYVCGTYAFQPKCTYINMLTFTLDRAEFEDGKGKCPYDPAKGHTGLLVDGELYSATLNNFLGTEPVILRYMGTHHSIKTEYLAFWLNEPHFVGSAFVPESVGSFTGDDDKIYFFFSERAVEYDCYSEQVVARVARVCKGDMGGARTLQKKWTTFLKARLVCSAPDWKVYFNQLKAVHTLRGASWHNTTFFGVFQARWGDMDLSAVCEYQLEQIQQVFEGPYKEYSEQAQKWARYTDPVPSPRPGSCINNWHRDNGYTSSLELPDNTLNFIKKHPLMEDQVKPRLGRPLLVKKNTNFTHVVADRVPGLDGATYTVLFIGTGDGWLLKAVSLGPWIHMVEELQVFDQEPVESLVLSQSKKVLFAGSRSQLVQLSLADCTKYRFCVDCVLARDPYCAWNVNTSRCVATTSGRSGSFLVQHVANLDTSKMCNQYGIKKVRSIPKNITVVSGTDLVLPCHLSSNLAHAHWTFGSQDLPAEQPGSFLYDTGLQALVVMAAQSRHSGPYRCYSEEQGTRLAAESYLVAVVAGSSVTLEARAPLENLGLVWLAVVALGAVCLVLLLLVLSLRRRLREELEKGAKASERTLVYPLELPKEPASPPFRPGPETDEKLWDPVGYYYSDGSLKIVPGHARCQPGGGPPSPPPGIPGQPLPSPTRLHLGGGRNSNANGYVRLQLGGEDRGGSGHPLPELADELRRKLQQRQPLPDSNPEESSV
What is the function of this protein?
Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling.  PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'.  Required for normal brain development, axon guidance and cell migration.  Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.
What are the official names of this protein?
Semaphorin-4C, M-Sema F, Semaphorin-C-like 1, Sema I, Semaphorin I.
What is the protein family that this protein belongs to?
Belongs to the semaphorin family.
What are the subcellular locations of this protein?
Postsynaptic density membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type I membrane protein.
Protein: BGLS_WICAO
Sequence: MLLPLYGLASFLVLSQAALVNTSAPQASNDDPFNHSPSFYPTPQGGRINDGKWQAAFYRARELVDQMSIAEKVNLTTGVGSASGPCSGNTGSVPRLNISSICVQDGPLSVRAADLTDVFPCGMAASSSFNKQLIYDRAVAIGSEFKGKGADAILGPVYGPMGVKAAGGRGWEGHGPDPYLEGVIAYLQTIGIQSQGVVSTAKHLIGNEQEHFRFAKKDKHAGKIDPGMFNTSSSLSSEIDDRAMHEIYLWPFAEAVRGGVSSIMCSYNKLNGSHACQNSYLLNYLLKEELGFQGFVMTDWGALYSGIDAANAGLDMDMPCEAQYFGGNLTTAVLNGTLPQDRLDDMATRILSALIYSGVHNPDGPNYNAQTFLTEGHEYFKQQEGDIVVLNKHVDVRSDINRAVALRSAVEGVVLLKNEHETLPLGREKVKRISILGQAAGDDSKGTSCSLRGCGSGAIGTGYGSGAGTFSYFVTPADGIGARAQQEKISYEFIGDSWNQAAAMDSALYADAAIEVANSVAGEEIGDVDGNYGDLNNLTLWHNAVPLIKNISSINNNTIVIVTSGQQIDLEPFIDNENVTAVIYSSYLGQDFGTVLAKVLFGDENPSGKLPFTIAKDVNDYIPVIEKVDVPDPVDKFTESIYVDYRYFDKYNKPVRYEFGYGLSYSNFSLSDIEIQTLQPFSENAEPAANYSETYQYKQSNMDPSEYTVPEGFKELANYTYPYIHDASSIKANSSYDYPEGYSTEQLDGPKSLAAGGLGGNHTCGMLVTLSLLKSQIKVLMLVGLHLNCMLDIQIMMNSQHLQCNYVDLKRCFWIKIILKLFLLN
What are the official names of this protein?
Beta-glucosidase, Beta-D-glucoside glucohydrolase, Cellobiase, Gentiobiase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
Protein: HRCA_FRASN
Sequence: MLEERRLEVLRAIVEDFVLSNEPVGSKTLAERHALGVSPATVRNDMSALEEEGYITQPHTSAGRIPTDKGYRLFVDRLSGVKPLSRAERRAIQSFLEGAVDLDDVVRRSVRLLAQLTRQVAVVQYPSLSSSSVRHIEIVTLNPNRLLLVLITDTGRVEQRVVDIPTPVDDGVVGELRGLLNGSLRGRRVVDATEVAADLPETVRPDLRPHLTTLTTVVLEALLERQEERVALAGTANLTRSSVDFADSLRFILEALEEQVVLLKLIGSARETGTVTVRIGRETDVDALRSTSVIATGYGLGPAVLGGMGVVGPMRMDYPGTMAAVRAVAKYVGELLGAD
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: DAPB_CHLTE
Sequence: MKITLVGNGRMGRQIADVVAASGAHVVNRVLDVNDTIDAAAFSGSDVIIDFTVRSAFLANYPALIASGVPVVVGTTGWDDVMPQVREEVVKARSTMLYSANYSLGVNIFFRTLREAARLIAPFEQFDIALSEQHHTGKADFPSGTAIKAADEILNSNPRKRTIVRELQEGRKLQSDELQVASIRLGSVFGVHSAIIDSESDTIELTHTAKNRTGFASGAVRAAEWLVQRHATSPGFYTMDDFLNDLFSA
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.