PharMolix/UniProtQA huggingface dataset:
Protein: SUCC_NITHX
Sequence: MNIHEYQAKALLREFGVPVSRGVPVLKASEAEAAAETLGGPVWVVKSQIHAGGRGKGKFKEASAGDKGGVRLAKSIDEVKQFASQMLGATLVTVQTGPAGKQVNRLYIEEGSDIDKEFYLSALVDRETSRVAFVVSTEGGVNIEDVAHTSPEKIVSFSVDPATGVMSHHGRTVAKALGLRGDLGKQAEKLVAQLYNAFIAKDMALLEINPLVVTRQGELRVLDAKVSFDDNALYRHPDAVALRDESEEDAKEIEASRFDLSYVALDGQIGCMVNGAGLAMATMDIIKLYGMSPANFLDVGGGATKDKVAAAFKIITADPNVKGILVNIFGGIMKCDVIAEGVVAAVKQVGLNVPLVVRLEGTNVDAGKKIIRESGLNVLPADDLDDAAQKIVKAVKG
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: GU38_RAT
Sequence: MYLFFSNLSFNDICIITTTIPKMLMNVQSHDQSITYLGCLSQVYLIVNFGSIESCLLAVMAYDRYVAICHPLKYTVIMNHYFCVMLLLFACSLALHMCLFHILMVLILTFCTKTEIPHFFCELAHIIKLTCSDNFINYLLIYTVSVLFFGVHIVGIILSYIYTVSSVLRMSLLGGMYKAFSTCGSHLSVVSLFYGTGFGVHISSPLTDSPRKTVVASVMYTVVTQMHGPFIYSL
What is the function of this protein?
Possible taste receptor.
What are the official names of this protein?
Putative gustatory receptor clone PTE38.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VF122_ASFWA
Sequence: MKICKACSSCMVRTYVDGNIIFRCSCGESVQGDSQNLLVSSKVYHTGEMEDKYKIFIKNAPFDPTNCQIKKDCPNCHLDYLTQICIGSQKIIILVCRCGYTSNRG
What are the official names of this protein?
Uncharacterized protein C122R, pC122R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus C122R family.
What are the subcellular locations of this protein?
Virion.
Protein: RHAR_SHIF8
Sequence: MAHQLKLLKDDFFASDQQAVAVADRYPQDVFAEHTHDFCELVIVWRGNGLHVLNDRPYRITRGDLFYIHADDKHSYASVNDLVLQNIIYCPERLKLNLDWQGAIPGFSASAGQPHWRLGSVGMAQARQVIGQLEHESSQHVPFANEMAELLFGQLVMLLNRHRYTSDSLPPTSSETLLDKLITRLAASLKSPFALDKFCDEASCSERVLRQQFRQQTGMTINQYLRQVRVCHAQYLLQHSRLLISDISTECGFEDSNYFSVVFTRETGMTPSQWRHLNSQKD
What is the function of this protein?
Activates expression of the rhaSR operon in response to L-rhamnose.
What are the official names of this protein?
HTH-type transcriptional activator RhaR, L-rhamnose operon transcriptional activator RhaR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU2M_SACBI
Sequence: MNPLIFTMIMLTVILGTTIVMMSSHWLMIWMGFEMNMLAVIPLLMKQYNPRSMEAATKYFLTQATASMLLMLAVIINLLYSGQWTFTKLMNPTASIIMTLALGMKMGLAPFHFWVPEVTQGISLSSGLILLTWQKLAPLSVLYVISPAINLDLILLMSMMSIAIGGWGGLNQTQLRKILAYSSIAHMGWMASILVFNPTMTLLNLLLYILMTTTTFMLFMVASATTTLSLSHMWNKMPLITTSTLTIMLSLGGLPPLTGFLPKWMIIQELTKNNNITLATLMAITALLNLFFYMRLTYATSLTMFPTTNNMKMKWQFNNKKQLKCLPVLIILSTITLPLAPAITLLN
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PAND_ECO5E
Sequence: MIRTMLQGKLHRVKVTHADLHYEGSCAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMKRTAKAIPVQVA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADE_CANAL
Sequence: MAQYECSEHMENFLRELPKCEHHVHLEGTLEPSLLFKLAKRNNITLPETFPKTVEECNDRYNRFADLQDFLDHYYIGMGVLITENDFYDLAMDYFTKAHSDGCLHSEVFFDPQGHVERNIDIDVVVQGFNRACKDANTKYGTTNKLIMCLLRHLPAENGLQTIHSASKYYQDGIIHGLGLDSSEKPFPPNLFTECYAHIKDNFPEVGLTAHAGEEGDHTFVSDALNLLKVSRIDHGVNSHQSEELMQRLAEQKTLLSLCPLSNVKLQVVKDVKELPIDKFFQMNVPFSINSDDPAYFGGYILDNYKAVHTRFGFTKDQWKIIALNGIKGSWCDDQRKNELISLVEEVYKKYNIEGC
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenine to hypoxanthine.  Plays an important role in the purine salvage pathway and in nitrogen catabolism.
What are the official names of this protein?
Adenine deaminase, ADE, Adenine aminohydrolase, AAH.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PEPT_CLOBH
Sequence: MKDVLERFLGYIKVDTQSSEESDTVPTTKTQLEFAKKLGEELKAIGLKDVSVDENGYVMATLESNIDKKVPTIGFIAHMDTSPDLSGTNINPRIVEKYDGQDIVLNKEKNIVLKINEFPEILEYKGQDIVVTDGNTLLGADDKAGIAEIITAMEYLINHPEIKHGTIKVGFTPDEEVGKGADHFDVKKFGADLAYTLDGGGIGELECETFNAAKAKVIIEGRNVHPGSAKNKMTNAVLVANKFINMLPENEVPERTEGYEGFFHLLSVKSEVETAELNYIIRDFDRKKFEERKEQIKEVGKKINEEYNKEIVCVKVEDQYYNMKEKIDEVKYVVDIAYDAMKAIDIEPILVPIRGGTDGSRLSFMGLPTPNLFAGGHNFHGRFEFVPVLSMEKAAELVVKIAELYANR
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6E_PYRAR
Sequence: MPTFKLVLSDPISGKAMQFEIKDPLAQRFVGLKIGDEIDGVILKDFISLPKGAKIKITGGSGIEGAPMVPGVPGPVKRYILAEGPPGYRPKKRGMRRKKLVRGDTISDSIVQINAVIVYPKDYSGPPAIPIGAKELEKLTKKEEAAAQ
What are the official names of this protein?
30S ribosomal protein S6e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS6 family.
Protein: MIAA_SALHS
Sequence: MNDVSKASLPKAIFLMGPTASGKTALAIELRKVLPVELISVDSALIYRGMDIGTAKPNADELKAAPHRLLDIRDPSQAYSAADFRRDALAQMAEITSAGRIPLLVGGTMLYFKALLEGLSPLPSADPEVRSRIEQQAAELGWEALHQQLQEIDPVAAARIHPNDPQRLSRALEVFFISGKTLTELTQTSGDALPYQVHQFAIAPASRELLHQRIELRFHQMLASGFEAEVRALFARGDLHTDLPSIRCVGYRQMWSYIEGEISYDEMVYRGVCATRQLAKRQMTWLRGWEGVRWLDSENPDRARKEVLQVVGAIAD
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: SYL_CAMFF
Sequence: MEYNAKNIEYKWQQIWKKNGYSEPKDDYSLPKKYILSMFPYPSGRLHMGHVRNYSIGDALSRYYRNRGYNVLQPIGFDSFGMPAENAAIKHKIHPKIWTYDNIDYMTKELDALGFSFSKKRLFATSDPLYTRWEQEFFIRMYEKGLVYRKSAVVNWCENDQTVLANEQVEDGKCWRCGHEVIQKEMPGYYLKITDYANELLECLKDLEGKWPNQVLTMQENWIGKSYGLEFEFKFDSSSKILLDGMDGFKVFTTRPDTIYGVSYAAIAPEHIVVKKLLEKNILDDATSAKLKFILNQSPKQRQSIDKDGVSLGLNVIHPLTNELIPVWCANFVLAEYGGGAVMSVPAHDERDFEFASKFNLNIKQIIKSDTLPYCEKSGVYINSELINGLAYEEAREKIISKFEKEGWGNRVTNYKLRDWGISRQRYWGAPIPMIHCKKCGVVPENISNLPVKLPDDVVITGEGNPLDKHSEFKNCKCPKCGSQATRETDTMDTFFESSWYFARFASDEKTWEDVAFDKKSVDYWMSVDQYIGGIEHAILHLLYARFFQKALRDLGYLRDCEPFDSLLTQGMVLKDGSKMSKSKGNTVDPDDIINKFGADTARLFILFAAPPQKELEWNDSAVEGAFKFINRLYDRSDNAYKTEILPQINHSNLNKDEKYARLKVYEALKKSTDVFENSFAFNTLIAACMEALNGLNAQNNKDIWTEGYFIILNLLEPIIPHACHELSNELFGLKNFTKLSLKDEVFVKDSLNLAITVNGKRRSEIEVSAFESDDKILEIAKQEVSKWIEGKEILKEIYVPNKLVNLVIKG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VKT19_ANOSM
Sequence: MMLLVLSISAILQVSHSVSFCLLPIVPGPCTQYVIRYAFQPSISACRRFTFGGCEGNDNNFMTRRDCEHYCEELL
What is the function of this protein?
May exert inhibitory effects on serine proteases and on potassium and/or calcium channels and then participate in the long-term non-lethal paralysis on the prey.
What are the official names of this protein?
Kunitz-type serine protease inhibitor As-fr-19, Asfr19.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: HMPTM_METJA
Sequence: MEKKTLSLCPICLKRIPATILEEDGKIIIKKTCPEHGEFKDIYWGDAELYKKFDKYEFIGKIEVTNTKVKNGCPYDCGLCPNHKSTTILANIDVTNRCNLNCPICFANANKSGKVYEPSFEDIKRMMENLRKEIPPTPAIQFAGGEPTVRSDLPELIKLARDMGFLHVQLATNGIKLKNINYLKKLKEAGLSTIYLQFDGISEKPYLVARGKNLLPIKQKVIENCKKVGFDSVVLVPTLVRGVNDNEVGGIIRYAAENVDVVRGINFQPVSFTGRVDEKTLLEGRITIPDFIKLVEEQTDGEITEEDFYPVPSVAPISVLVEKLTNDRKPTLSSHQHCGTSTYVFVDEDGKLIPITRFIDVEGFLEIVKEKIEEIGKSKMHDVKVLGEIALKLPSLIDLDKAPKSVNIKKIIDLILSVLKSDYSALAELHYHMLMISCMHFMDAYNFDVKRVMRCCIHYATPDDRIIPFCTYNTLHRQEVEEKFSIPLEEWKRMHKIGGEDDREDY
What is the function of this protein?
Is responsible for the addition of methyl groups at C-7 and C-9 of the pterin ring during methanopterin (MPT) biosynthesis.  Catalyzes methylation of 7,8-dihydro-6-hydroxymethylpterin, likely using methylenetetrahydromethanopterin as a methyl group donor, via a radical-based mechanism.
What are the official names of this protein?
7,8-dihydro-6-hydroxymethylpterin dimethyltransferase, 6-hydroxymethyl-H(2)pterin dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily.
Protein: VSP2_GLOHA
Sequence: MVLIKVLANLLILQLSYAQKSSELIIGGDECNINEHRFLVALYTSRTLFCGGTLINQEWVLTAAHCNMEDIQIKLGMHSKKVPNEDEQKRVPKEKFFCLSSKNYTLWDKDIMLIRLDSPVKNSAHIAPLSLPSSPPSVGSVCRTMGWGRISSTKETYPDVPHCVNINLLEYEMCRAPYPEFELPATSRTLCAGILEGGKDTCVGDSGGPLICNGQFQGIASWGDDPCAQPHKPAAYTKVFDHLDWIENIIAGNTDASCPP
What is the function of this protein?
Snake venom serine protease that may act in the hemostasis system of the prey.
What are the official names of this protein?
Snake venom serine protease pallabin-2, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DCUP_MICAN
Sequence: MTDSPEIPYLLRAAKGEILPRPPVWMMRQAGRYMQIYRELRDKYPSFRERSENADLAIEISLQPWRAFQPDGVIMFSDILTPLAGIGIPFDIIESKGPIIDSPIRTQAQVDQLNPLDPDQSLPFIKTILKTLRQEVGNKSTVLGFVGAPWTLAAYAVEGKGSKSYSVIKGMAFSEPSVLHQFLDKLADMIATYVRYQIDCGAQVVQMFDSWAGQLTPQDYDVFALPYQQKVVRLVKETHPDTPLILYISGSAGVLERMGKSGVDIISVDWTVDLAEARQRLGKAMMVQGNIDPGVLFGSQSFIRERIIDTIRKAGNQGHILNLGHGVLVGTPEDNVRFFFETAKQFSYQD
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF3_SALAR
Sequence: MTLSPYLQEVAKRRTFAIISHPDAGKTTITEKVLLFGQAIQTAGTVKGRGSSQHAKSDWMEMEKQRGISITTSVMQFPYHDCLVNLLDTPGHEDFSEDTYRTLTAVDCCLMVIDAAKGVEDRTRKLMEVTRLRDTPILTFMNKLDRDIRDPMELLDEVENELKIGCAPITWPIGCGKLFKGVYHLYKDETYLYQTGKGHTIQEVRIVKGLNNPDLDAAVGEDLAQQLRDELELVQGASNEFDKDLFLAGEITPVFFGTALGNFGVDHMLDGLVEWAPAPMPRQTDTRTVEASEEKFSGFVFKIQANMDPKHRDRVAFMRVVSGKYEKGMKLRQVRTGKDVVISDALTFMAGDRSHVEEAYPGDILGLHNHGTIQIGDTFTQGEMMKFTGIPNFAPELFRRIRLKDPLKQKQLLKGLVQLSEEGAVQVFRPISNNDLIVGAVGVLQFDVVVARLKSEYNVEAIYESVNVATARWVESTDAKKFEEFKRKNETQLALDGGDNLTYIAPTMVNLNLTQERYPDVQFRKTREH
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPS_MYCMM
Sequence: MGIVGVGIDLVSIPDFAEQVDQPGTAFAATFTPGERRDASDKSSSAARHLAARWAAKEAVIKAWSGSRFAQRPVLPEDIHRDIEVVTDMWGRPRVRLTGEIAKHLADVTIHVSLTHEGDTAAAVAILETS
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S6A15_RAT
Sequence: MPKNSKVVKRDLDDDVIESVKDLLSNEDSVEDVSKKSELIVDVQEEKDTDAEDGSEVDDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLLVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWTLFYFSQSFQQPLPWDQCPLVKNASHTYIEPECEKSSATTYYWYREALAISSSISESGGLNWKMTGCLLAAWVMVCLAMIKGIQSSGKIMYFSSLFPYVVLICFLIRSLLLNGSIDGIRHMFTPKLEMMLEPKVWREAATQVFFALGLGFGGVIAFSSYNKRDNNCHFDAVLVSFINFFTSVLATLVVFAVLGFKANIVNEKCISQNSEMILKLLKTGNVSWDVIPRHINLSAVTAEDYHVVYDIIQKVKEEEFAVLHLKACQIEDELNKAVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLINLGLGSMFGTIEGIITPVVDTFKVRKEILTVICCLLAFCIGLMFVQRSGNYFVTMFDDYSATLPLLIVVILENIAVSFVYGIDKFLEDLTDMLGFAPSKYYYYMWKYISPLMLVTLLIASIVNMGLSPPGYNAWIKEKASEEFLSYPMWGMVVCFSLMVLAILPVPVVFVIRRCNLIDDSSGNLASVTYKRGRVLKEPVNLDGDDASLIHGKIPSEMSSPNFGKNIYRKQSGSPTLDTAPNGRYGIGYLMADMPDMPESDL
What is the function of this protein?
Functions as a sodium-dependent neutral amino acid transporter.  Exhibits preference for the branched-chain amino acids, particularly leucine, valine and isoleucine and methionine.  Can also transport low-affinity substrates such as alanine, phenylalanine, glutamine and pipecolic acid.  Mediates the saturable, pH-sensitive and electrogenic cotransport of proline and sodium ions with a stoichiometry of 1:1.  May have a role as transporter for neurotransmitter precursors into neurons.  In contrast to other members of the neurotransmitter transporter family, does not appear to be chloride-dependent.
What are the official names of this protein?
Sodium-dependent neutral amino acid transporter B(0)AT2, Solute carrier family 6 member 15, Transporter v7-3, sodium- and chloride-dependent neurotransmitter transporter NTT73.
What is the protein family that this protein belongs to?
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A15 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PANB_HYPNA
Sequence: MSKQTQTTRKTVKDIAAAKGATPLVMLTAYDAPTAAILDPHCDILLVGDSLGMVVHGLPSTVGVTMEMMILHGQAVMRGASQAMVVVDMPFGSYETNADQAFLNAVRIMKETGCQAIKIESGAYAAGQIAHLVERGIPVMGHIGLRPQAINVDGGFRAKGRTEDERDRVIAEARAAADAGAFCIVIEGVAEDLAAAITAEVSCPTIGIGASAACDGQVLVTQDMLGLFDWTPKFVRRYADLREVVDKAAAEYAADVRARRFPGTAETYSLRKQGS
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBD_METTH
Sequence: MSEVSVLLLAVILDLLIGEPPHRLHPVVWMGSAVEWMRNILGNSRISGIILTIAVAAPFTLPLFLINHLQDPLNLIISSILLSAVISIRMLVTSALEVGGSLKEDIEDARRKLSMLVSRDTTSLSDEQITSAAIETLTENITDSVTAPIFYFILLGLPGAFLYRVVNTLDAMVGYLDSENRDIGWFPARLDDILNYIPSRITGVLMVPAALLLGMNWRGSFRILLRDARRTPSPNSGFTMAAAAGALSVQLEKPGVYVLGDPCDGLDNEKLLDAVKLSSLTLILFTLAAAGVMLVIP
What is the function of this protein?
Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
What are the official names of this protein?
Probable cobalamin biosynthesis protein CobD.
What is the protein family that this protein belongs to?
Belongs to the CobD/CbiB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CATZ_HUMAN
Sequence: MARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCEGGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRIVTSTYKDGKGARYNLAIEEHCTFGDPIV
What is the function of this protein?
Exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity (PubMed:10504234).  Capable of producing kinin potentiating peptides (By similarity).
What are the official names of this protein?
Cathepsin Z, Cathepsin P, Cathepsin X.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: PSTB_CORGL
Sequence: MSKLKLNDVNIYYGDFHAVQNVNLEVPARSVTAFIGPSGCGKSTVLRSINRMHEVTPGAYVKGEILLDGENIYGSKIDPVAVRNTIGMVFQKANPFPTMSIEDNVVAGLKLSGEKNKKKLKEVAEKSLRGANLWEEVKDRLDKPGGGLSGGQQQRLCIARAIAVEPEILLMDEPCSALDPISTLAVEDLIHELKEEFTIVIVTHNMQQAARVSDQTAFYSLEATGRPGRLVEIGPTKKIFENPDQKETEDYISGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: DCNL5_BOVIN
Sequence: MPVKKKRKSGVAAAAAEDGGLKKCKISSYCRSQPPARLISGEEHFSSKKCLAWFYEYAGPDEVVGPEGMEKFCEDIGVEPENIIMLVLAWKLEAESMGFFTKEEWLKGMTSLQCDCTEKLQNKFDFLRSQLNDISSFKNIYRYAFDFARDKDQRSLDIDTAKSMLALLLGRTWPLFSVFYQYLEQSKYRVMNKDQWYNVLEFSRTVHADLSNYDEDGAWPVLLDEFVEWHKVRQAS
What is the function of this protein?
Contributes to the neddylation of all cullins by transferring NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes which is necessary for the activation of cullin-RING E3 ubiquitin ligases (CRLs).  May play a role in DNA damage response and may participate in cell proliferation and anchorage-independent cell growth.
What are the official names of this protein?
DCN1-like protein 5, DCUN1 domain-containing protein 5, Defective in cullin neddylation protein 1-like protein 5, Squamous cell carcinoma-related oncogene 5.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Note=Subcellular localization is independent of the interaction with cullins.
Protein: EFM4_SCHPO
Sequence: MSGLPESKLGTKQYWDNVYEREVSNFTEFNDEGEVWFGEEAEERIVQWLEDHISTSFREVSEAAPFRVLDLGTGNGHLLFRLLEEEDTLLPSPCQLVGVDYSEAAIVLAKNIARHRQFSDKVKFQQLDIIKDSKFCSKDWDLILDKGTFDAISLSGELLDGRPLNSVYVDRVRGMLSPNGIFLITSCNWTIQELEERFTKNGFIVHSTVPVPVFEFQGSTGSSTSVIAFQIDPSFNRK
What is the function of this protein?
S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that mono- and dimethylates elongation factor 1-alpha at 'Lys-316'.  May play a role in intracellular transport.
What are the official names of this protein?
Protein-lysine N-methyltransferase efm4, Elongation factor methyltransferase 4, Secretion and early endocytosis protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MCH1_ASHGO
Sequence: MSLSSLEHKLTYHVRNWLHGSGFAWNTLHMSAFLVALCACIPAGFISQISLYSEPWREHLGYSVVEVNVLFSAVNLGGYITPPLLGLLSDAHGPVMLSWLSFVGFVPTYAYAAWVFASGEPHFYASVLCFTLIGISTNALYFSALFTASKLYPASKLCSISLPATFYGMASVLGSQLLKIPWFRNGLPYLDLSRVFRTLAVAYTLISFCMWFATSIVTMLKVKAATLTFAGMQSPTEPLLPQDIRRRLRNFFHDPAAYFMALVLLLSLGPMEMFLTNMGSLSSLLGQASVLPEFAIASTCSRFLSGLIIDLCIHNGVSTMSVQWAVLLLGVVGQWIVVLATRASDGPLLSLASALSGACYGGLFTVSPILTLAVWGDAVFGTAYGSFMITPAVGSILFGLTYAHIFDANCTPSGVLPVCIQHVFWSSTSALAIALLFSVLMYLVFWRRKV
What is the function of this protein?
Probable transporter.
What are the official names of this protein?
Probable transporter MCH1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: U71D2_ARATH
Sequence: MRNAELIFIPTPTVGHLVPFLEFARRLIEQDDRIRITFLLMKQQGQSHLDSYVKTISSSLPFVRFIDVPELEEKPTLGTQSVEAYVYDFIETNVPLVQNIIMGILSSPAFDGVTVKGFVADFFCLPMIDVAKDASLPFYVFLTSNSGFLAMMQYLAYGHKKDTSVFARNSEEMLSIPGFVNPVPAKVLPSALFIEDGYDADVKLAILFTKANGILVNTSFDIEPTSLNHFLGEENYPSVYAVGPIFNPKAHPHPDQDLACCDESMKWLDAQPEASVVFLCFGSMGSLRGPLVKEIAHGLELCQYRFLWSLRTEEVTNDDLLPEGFMDRVSGRGMICGWSPQVEILAHKAVGGFVSHCGWNSIVESLWFGVPIVTWPMYAEQQLNAFLMVKELKLAVELKLDYSVHSGEIVSANEIETAISCVMNKDNNVVRKRVMDISQMIQRATKNGGSSFAAIEKFIHDVIGTRT
What are the official names of this protein?
UDP-glycosyltransferase 71D2.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: PYRF_STRU0
Sequence: MREQRPIIALDFPDFDTLKDFLNQFPKDEALYVKIGMELYYAVGPEIVRYVKSLGHSVFLDLKLHDIPNTVKSTMKVLAKMGIDMTTVQAAGGVEMLEAAREGLGDDPILIAVTQLTSTSEEQMREDQNIQTTLTESVLHYAKRTALAKLDGVVCSAHEVEAIKSVTSKDFLCLTPGIRPKGTDIGDQKRVMTPQEAKAIGSDFIVVGRPITQAPDPLAAYHAIKADWNA
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: BPIFC_HUMAN
Sequence: MCTKTIPVLWGCFLLWNLYVSSSQTIYPGIKARITQRALDYGVQAGMKMIEQMLKEKKLPDLSGSESLEFLKVDYVNYNFSNIKISAFSFPNTSLAFVPGVGIKALTNHGTANISTDWGFESPLFQDTGGADLFLSGVYFTGIIILTRNDFGHPTLKLQDCYAQLSHAHVSFSGELSVLYNSFAEPMEKPILKNLNEMLCPIIASEVKALNANLSTLEVLTKIDNYTLLDYSLISSPEITENYLDLNLKGVFYPLENLTDPPFSPVPFVLPERSNSMLYIGIAEYFFKSASFAHFTAGVFNVTLSTEEISNHFVQNSQGLGNVLSRIAEIYILSQPFMVRIMATEPPIINLQPGNFTLDIPASIMMLTQPKNSTVETIVSMDFVASTSVGLVILGQRLVCSLSLNRFRLALPESNRSNIEVLRFENILSSILHFGVLPLANAKLQQGFPLSNPHKFLFVNSDIEVLEGFLLISTDLKYETSSKQQPSFHVWEGLNLISRQWRGKSAP
What are the official names of this protein?
BPI fold-containing family C protein, Bactericidal/permeability-increasing protein-like 2, BPI-like 2.
What is the protein family that this protein belongs to?
Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
What are the subcellular locations of this protein?
Secreted.
Protein: HEMH_THIDA
Sequence: MKYAEEPEYAHGTPLCAGVLLVNLGTPEAPTAAALRPYLKEFLSDPRVVEIPRALWWLVLNGIILNTRPRKSAEKYAAIWTSEGSPLKVHTEKQAKLLKGWLGEHAAAPVVVDYAMRYGRPGIPEVLARMKAAGCDRILVLPAYPQYAASSTATAFDAAFDWLRRTRNQPALRTLKHYHDHPEYIRALAANLRDYWQMHGRPDVLVMSFHGVPRYTLDKGDPYHCECQKTARLLAAALGLEPGQFRVTFQSRFGRAEWLKPYTDKTLEALGREGVGRVDVVAPGFTADCLETLEELAMEGRASFLAAGGKEFHYVPALNEHPQWIAALGRIALANLAGWLDEGWTPDADEASRQLSRSRALALGAQR
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.