PharMolix/UniProtQA huggingface dataset:
Protein: RS2_PARUW
Sequence: MAQNKNQTLPISIKDLLEAGAHFGHQTSRWNPKMKRFIFEERNGLYIIDLAKTLQQIRNAVDIVRDVVAKHKSILFVGTKKQAKAVLRELSEQCGEFYVCERWLGGMLTNLSTIRQSVKKLERIEKRISTGGEGLTKKEISLLTKDQIKLEKNLSGVRSMRKPPGLVIVVDPSKEHLAVAEANKLGIPVMGLVDTNCDPDPIEHVIACNDDALKSIKLILETLAKAIIDKKNDIKVYASKEEQTEEAEEETLSSKYREQDFQEAKSGARGEK
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: ATGT_HALMA
Sequence: MTNFEVRQYDAAGRLGELTVPRAGVTVETPTILPVVNPHVQTVAPATLASEFGAEILITNSYILHGSDDLREPVLEQGLHDLLGFDGAIMTDSGSFQLAEYGDIDVTTEEILEFQHEIGSDIGTPVDIPTPPDVDRERATEELKTTQERLEHAATVDTGEMLVSAPVQGATYPDLRERAAADAVSTGLDVFPLGAVVPLMNEYRYADLADVVAACKRGLGEVGPVHLFGAGHPMMFAMAAALGCDLFDSAAYALYARDDRYLTVQGTELLDELSYFPCHCPVCTDHTPAELDAMDADAREELLARHNLHVTYGEIRTVKQAIRSGNLMELVDSRARGHPEMLDGYRALLDHSEQLERTDPVSKDAFFYTSTESARRPEVRRHQDRLERLPVEGEEVLLTEGSSSAQYDESWGVLPPFGPYPRELADTYPLTAETPDRTDRAAYEAAATGVRRLVELHPDVSFTLVHDDWPATALDRVPEGVRLRDLHARD
What is the function of this protein?
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
What are the official names of this protein?
tRNA-guanine(15) transglycosylase, 7-cyano-7-deazaguanine tRNA-ribosyltransferase, Archaeal tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the archaeosine tRNA-ribosyltransferase family.
Protein: DAPE_COXBN
Sequence: MSETLNLLKQLIERPSITPNDAGCQTILIDRLKSVGFQCEHLPFGEVHNFWAWHGHQSPFIIFAGHTDVVPPGDETQWHSPPFTPTEKNGYIYGRGAADMKSGLAAMVVAAENFVKQNPDHNGTIGFIVTSDEEGPAENGTQKVVDYLQQKNIKLDYCIVGEASSNEKLGDAIKIGRRGSMHGELTIIGKQGHIAYPHLADNPIHRSFQAFEALAKTKWDEGNEHFTPTSFQFYNVEAGAGAANVIPATLKAKFNFRFAPIHTTQQLQQKVERILNYYQLNYDIQWNVSSQPFFSGNGRLATFVRQAIQEICHLNTEPNTYGGTSDGRFIATTGCEVIELGPVNKTAHHVNENICIADLEKLTDIYFRTLQLLT
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: MTNN_SALEP
Sequence: MKIGIIGAMEEEVTLLRDKIDNRQTITLGGCEIYTGQLNGTEVALLKSGIGKVAAALGATLLLEHCKPDVIINTGSAGGLASTLKVGDIVVSDEARYHDADVTAFGYEYGQLPGCPAGFKADDKLIAAAESCIRELNLNAVRGLIVSGDAFINGSVGLAKIRHNFPDAVAVEMEATAIAHVCYNFSVPFVVVRAISDVADQQSHLSFDEFLAVAAKQSTLMVETLVQKLAHG
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.  Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: NUOH_LEPBP
Sequence: MDWALILAWGIKILSLFFVILTGVAYYTLAERKFAGFIQDRPGPNRAGPFGIFQPLADGIKFIAKEEIFPKNVSKGMYLLAPTISMTCAIMAWAVIPFGGTLPAPEWLTTLTGVATIDLQIANPDSGVLYMLAISSLSVYGIMIAGWSSNNKYSLLGGVRSTAQMISYELPMGLSIVAIVIMTGSLKLTDISDSQKDMWNILSPPGFVAFFIYVTAMFAETNRLPFDLAEAESELVVGFHTEYGAFKFALFFLAEYMNMITMSCLTTLLFFGGYNVPFQLGAGSEYQAFIGLGFFILKVLFFAFLFIWVRWTLPRFRYDQLMKLGWKKMIPWGLFVVMFASIYTVYWKEGWMKLFI
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ODR4_HUMAN
Sequence: MGRTYIVEETVGQYLSNINLQGKAFVSGLLIGQCSSQKDYVILATRTPPKEEQSENLKHPKAKLDNLDEEWATEHACQVSRMLPGGLLVLGVFIITTLELANDFQNALRRLMFAVEKSINRKRLWNFTEEEVSERVTLHICASTKKIFCRTYDIHDPKSSARPADWKYQSGLSSSWLSLECTVHINIHIPLSATSVSYTLEKNTKNGLTRWAKEIENGVYLINGQVKDEDCDLLEGQKKSSRGNTQATSHSFDVRVLTQLLLNSDHRSTATVQICSGSVNLKGAVKCRAYIHSSKPKVKDAVQAVKRDILNTVADRCEMLFEDLLLNEIPEKKDSEKEFHVLPYRVFVPLPGSTVMLCDYKFDDESAEEIRDHFMEMLDHTIQIEDLEIAEETNTACMSSSMNSQASLDNTDDEQPKQPIKTTMLLKIQQNIGVIAAFTVAVLAAGISFHYFSD
What is the function of this protein?
May play a role in the trafficking of a subset of G-protein coupled receptors.
What are the official names of this protein?
Protein odr-4 homolog, hODR-4, LAG1-interacting protein, Transactivated by transforming growth factor beta protein 1.
What is the protein family that this protein belongs to?
Belongs to the ODR-4 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL4_HAEIN
Sequence: MELQVVGANALTVSETTFGREFNEALIHQVVVAYAAGARQGTRAQKTRAEVSGSGKKPWRQKGTGRARAGDIKSPIWRSGGTTFAAKPQDHSQKVNKKMYRGAIKSILSELVRQDRLVVVEKFELDAPKTKVLVQKLKDLAVEDALIITASLDENLFLAARNLYKVDVRDVQGIDPVSLIAFDKVIVTVDAVKQIEEILA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: COAD_THIDA
Sequence: MLTAVYPGTFDPITRGHEDLVRRAVRLFDRVVVAVAESRNKRPFFSMDERVAMTREVLADVPQVRVEGFSGLLIDFVAEQGAIAVLRGLRAASDFEYEFQLAGMNRNLKPDIETLFLTPSEQYMFISASMIREIAQFGGDVTPFVHPLVARRLSEKIREN
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFSA_METRJ
Sequence: MQFAAPLVPGRLVQRYKRFLADIDTDDGRVTVHCPNPGAMLGLNAPGARVLLSRSSNPARKLPLTWELVEAELPGGAQWVGINTQRPNALVAEAFRAGAIAALAGHDALRPEVRYAEASRVDFLASGAEAGPCHVEVKNCHLMRRAGLAEFPDCKAARSARHMRDLAQVVADGGRALVVIVVQMRAEAFDVARDIDPAFDRAFREARAAGVAVRAYRCAVGPEGVAIAEEIPVITPP
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: MEND_STAAN
Sequence: MGNHKAALTKQVFTFASELYAYGVREVVISPGSRSTPLALAFEAHPNIKTWIHPDERSAAFFAVGLIKGSERPVAILCTSGTAAANYTPAIAESQISRIPLIVLTSDRPHELRSVGAPQAINQVNMFNNYVSYEFDMPIADDSKETINAIYYQMQIASQYLYGPHKGPIHFNLPFRDPLTPDLNATELLTSEMKILPHYQKSIDASALRHILNKKKGLIIVGDMQHQEVDQILTYSTIYDLPILADPLSHLRKFDHPNVICTYDLLFRSGLDLNVDFVIRVGKPVISKKLNQWLKKTDAFQILVQNNDKIDVFPIAPDISYEISANDFFRSLMEDTTINRVSWLEKWQCLEKKGRKEIKCYLEQATDESAFVGELIKKTSEKDALFISNSMPIRDVDNLLLNKNIDVYANRGANGIDGIVSTALGMAVHKRITLLIGDLSFYHDMNGLLMSKLNNIQMNIVLLNNDGGGIFSYLPQKESATDYFERLFGTPTGLDFEYTAKLYQFDFKRFNSVSEFKNATLLSETSTIYELITNREDNFKQHQILYQKLSEMIHDTL
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: ARGB_PSEAB
Sequence: MTLSRDDAAQVAKVLSEALPYIRRFVGKTLVIKYGGNAMESEELKAGFARDVVLMKAVGINPVVVHGGGPQIGDLLKRLSIESHFIDGMRVTDAATMDVVEMVLGGQVNKDIVNLINRHGGSAIGLTGKDAELIRAKKLTVTRQTPEMTKPEIIDIGHVGEVTGVNVGLLNMLVKGDFIPVIAPIGVGSNGESYNINADLVAGKVAEALKAEKLMLLTNIAGLMDKQGQVLTGLSTEQVNELIADGTIYGGMLPKIRCALEAVQGGVTSAHIIDGRVPNAVLLEIFTDSGVGTLISNRKRH
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_SALPA
Sequence: MKPSIVAKLEALHERHEEVQALLGDAGIIADQDRFRALSREYAQLSDVSRCFTDWQQVQDDIETAQMMLDDPEMREMAQEELREAKEKSEQLEQQLQVLLLPKDPDDERNAFLEVRAGTGGDEAALFAGDLFRMYSRYAEARRWRVEIMSMSEGEHGGYKEIIAKISGDGVYGRLKFESGGHRVQRVPATESQGRIHTSACTVAVMPELPEAELPDINPADLRIDTFRSSGAGGQHVNTTDSSIRITHLPTGIVVECQDERSQHKNKAKALSVLGARIHAAETAKRQQAEASTRRNLLGSGDRSDRNRTYNFPQGRVTDHRINLTLYRLDETMEGKLDMLIEPIVQEHQADLLAALSEQE
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NOP53_HUMAN
Sequence: MAAGGSGVGGKRSSKSDADSGFLGLRPTSVDPALRRRRRGPRNKKRGWRRLAQEPLGLEVDQFLEDVRLQERTSGGLLSEAPNEKLFFVDTGSKEKGLTKKRTKVQKKSLLLKKPLRVDLILENTSKVPAPKDVLAHQVPNAKKLRRKEQLWEKLAKQGELPREVRRAQARLLNPSATRAKPGPQDTVERPFYDLWASDNPLDRPLVGQDEFFLEQTKKKGVKRPARLHTKPSQAPAVEVAPAGASYNPSFEDHQTLLSAAHEVELQRQKEAEKLERQLALPATEQAATQESTFQELCEGLLEESDGEGEPGQGEGPEAGDAEVCPTPARLATTEKKTEQQRRREKAVHRLRVQQAALRAARLRHQELFRLRGIKAQVALRLAELARRQRRRQARREAEADKPRRLGRLKYQAPDIDVQLSSELTDSLRTLKPEGNILRDRFKSFQRRNMIEPRERAKFKRKYKVKLVEKRAFREIQL
What is the function of this protein?
Nucleolar protein which is involved in the integration of the 5S RNP into the ribosomal large subunit during ribosome biogenesis (PubMed:24120868).  In ribosome biogenesis, may also play a role in rRNA transcription (PubMed:27729611).  Also functions as a nucleolar sensor that regulates the activation of p53/TP53 in response to ribosome biogenesis perturbation, DNA damage and other stress conditions (PubMed:21741933, PubMed:24120868, PubMed:27829214).  DNA damage or perturbation of ribosome biogenesis disrupt the interaction between NOP53 and RPL11 allowing RPL11 transport to the nucleoplasm where it can inhibit MDM2 and allow p53/TP53 activation (PubMed:24120868, PubMed:27829214).  It may also positively regulate the function of p53/TP53 in cell cycle arrest and apoptosis through direct interaction, preventing its MDM2-dependent ubiquitin-mediated proteasomal degradation (PubMed:22522597).  Originally identified as a tumor suppressor, it may also play a role in cell proliferation and apoptosis by positively regulating the stability of PTEN, thereby antagonizing the PI3K-AKT/PKB signaling pathway (PubMed:15355975, PubMed:16971513, PubMed:27729611).  May also inhibit cell proliferation and increase apoptosis through its interaction with NF2 (PubMed:21167305).  May negatively regulate NPM1 by regulating its nucleoplasmic localization, oligomerization and ubiquitin-mediated proteasomal degradation (PubMed:25818168).  Thereby, may prevent NPM1 interaction with MYC and negatively regulate transcription mediated by the MYC-NPM1 complex (PubMed:25956029).  May also regulate cellular aerobic respiration (PubMed:24556985).  In the cellular response to viral infection, may play a role in the attenuation of interferon-beta through the inhibition of RIGI (PubMed:27824081).
What are the official names of this protein?
Ribosome biogenesis protein NOP53, Glioma tumor suppressor candidate region gene 2 protein, Protein interacting with carboxyl terminus 1, PICT-1, p60.
What is the protein family that this protein belongs to?
Belongs to the NOP53 family.
Protein: PIMT_ANADE
Sequence: MSRELAEWLGHMGIRDRRVLDAIAELDRARFVPPHLVAEAYADRPLPIGFGQTISQPFVVAFMTEALGLDGGERVLEVGTGSGYQTALLARLAGEVWSVEIVPGLAARARALLLGDLGLANVHLREGDGALGWPEAAPFDRILVTAAAPQVPPPLRAQLAPGGRMVLPVGEAESEQVLRVLERAADGIEEIEDLLPVRFVPLTHLPPAV
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRF_SHEON
Sequence: MTTKPILVALDYDNKNHALQLIDQLDPNMCRLKVGKEMFTLFGPQLVKDIHERGFDLFLDLKFHDIPNTVAKAVTAAAELGVWMTNVHASGGLAMMEAAKKALQPYGKEAPMLIAVTVLTSMSDEDLKLIGIDVPAFEHVQRLAKLTKQAELDGVVCSAQEASILKSLLGQDFKLITPGIRPVGSDVGDQHRVMTPPEALAAGADYLVIGRPITKATDPLAALQAIHQSLV
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: MINE_AZOSB
Sequence: MSLLARLFGEKKKTAEIAKNRLSLLIAHERSGGAGTADFLPALQKDLIDVISKYVNVNPDDIKVQLDKQDNVEVLEVNIVLPEHGR
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: IDI2_BACCQ
Sequence: MVRAKRKLDHIEYALSTGQSRTHGFHDIDFVHQSLPNSNYDTITCETKIGELSLSSPIFINAMTGGGGEKTLHINEQLAYVAKHHNLAMAVGSQMAALKDESEAASYKIIRKVNPNGIFFANLGSEATVEQAERAVDMVEANALQIHLNVIQELTMPEGDRDFTGVLQRIEKIVLNSKVPVIVKEVGFGMSKETMQQLASVGVTAIDIGGQGGTNFAAVENERRQRMLSYFNNWGIQTATSIIEATSTNNNLSFIASGGIQTALDVAKAIALGANTTAFAGYFLRILMQDGIEKLVDEIDLLHADLKFIMTALGAKTIEELQSVPLVVKGETYHWLTQRGIDTTHYSRR
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASTD_ECOUT
Sequence: MTLWINGDWVTGQGALRVKRNPVSGEVLWQGNDADAAQVGQACRAARAAFPRWARLSFGDRQVRVERFAGLLESNKAELTAIIARETGKPRWEAATEVTAMINKIAISIKAYHVRTGEQRSEMPDGAASLRHRPHGVLAVFGPYNFPGHLPNGHIVPALLAGNTIIFKPSELTPWSGDAVMRLWQQAGLPPGVLNLVQGGRETGQALSALEDLDGLLFTGSANTGYQLHRQLSGQPEKILALEMGGNNPLIIDEVADIDAAVHLTIQSAFVTAGQRCTCARRLFLKSGTQGDAFLARLVAVSQRLTPGTWDDEPQPFIGGLISEQAAQQVVTAWQELEAMGGRTLLAPRLLQAGTSLLTPGIIEMTGVTGLPDEEVFGPLLRVWRYDNFDEAIRMANNTRFGLSCGLVSPEREKFDQLLLEARAGIVNWNKPLTGAASTAPFGGIGASGNHRPSAWYAADYCAWPMASLESDSLTLPATLNPGLDFSDEVVR
What is the function of this protein?
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
What are the official names of this protein?
N-succinylglutamate 5-semialdehyde dehydrogenase, Succinylglutamic semialdehyde dehydrogenase, SGSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. AstD subfamily.
Protein: RF1_ACAM1
Sequence: MAEAYLLEKLKSVEQTFHELTRRLGDPEVATNPTEFQEVAKARASLEETVNTFEDWKATQQELADAQQMAKDGDEDPELKEMAAMEAAELTEKLDGLETKLKVLLLPRDPNDEKNIMLEIRAGAGGDEASIWAGDLVRIYSKYAESQKWRVKLLSESGGEMGGFKEAILEIQGERVYSKLKYEAGVHRVQRVPATEASGRVHTSTATVAVMPEVDDVEIEIDPKDIEMSTARSGGAGGQNVNKVETAVDLVHKPTGIRIFCTEERSQLQNKERAMQILRAKLYEMELQEQQASVTSMRRSQVGTGARSEKIRTYNYKDNRATDHRLNQNFPLEKVLVGDIELILETCIAQDQQAQLADLAAAV
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4860_BACAN
Sequence: MKVSYHGHSVVKIETNGKVILIDPFLTGNPKTDLKAEDVKVDAILLSHGHGDHVGDTVELAKKNNAVVVAPFELATFLSWQGVNTHPMHIGGSHEFDFGKVKFTQAFHGSSYIDEENKTITYTGMPAGILFTAEEKTLYHAGDTALFSDMKLIGELNNIDVAFLPIGDNFTMGPEDAVLAAKWVQAKTVVPMHYNTFPVIEQDPYQFVEKLQNCTGKVLEAGESITL
What are the official names of this protein?
UPF0173 metal-dependent hydrolase BA_4860/GBAA_4860/BAS4507.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: NUOH_PARDP
Sequence: MAEFWASPYGFALSMLLQGLAVIAFVMGSLIFMVYGDRKIWAAVQMRRGPNVVGPWGLLQTFADALKYIVKEIVIPAGADKFVYFLAPFLSMMLALFAFVVIPFDEGWVMANINVGILFIFAASSLEVYGVIMGGWASNSKYPFLASLRSAAQMISYEVSLGLIIIGIIISTGSMNLTAIVEAQRGDYGLLNWYWLPHLPMVVLFFVSALAECNRPPFDLVEAESELVAGFMTEYSSTPYLLFMAGEYIAMYLMCALLSLLFFGGWLSPVPFIADGWWWMVIKMWFWFYMFAMVKAIVPRYRYDQLMRIGWKVFLPLSLGWVVLVAILARYEILGGFWARFAVGG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit 8, NADH dehydrogenase I subunit H, NADH-quinone oxidoreductase subunit 8, NQO8, NDH-1 subunit 8, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MRAZ_DESHD
Sequence: MFMGEYLHTIDGKGRLIVPARFREALGERFIATKGLDHCLFVYPLDEWKVLEEKLRALPFTQPEARAFVRFFFSGATECELDKQGRILLPANLREYAQLDKDAVLVGVSSRVEIWSQALWANYSRQAEDAYASAAESLVNLGI
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: AP1S1_YEAST
Sequence: MTQLKYLLLVSRQGKIRLKKWYTAMSAGEKAKIVKDLTPTILARKPKMCNIIEYNDHKVVYKRYASLYFIVGMTPDVDNELLTLEIIHRFVETMDTYFGNVCELDIIFNFSKVYDILNEMIMCDGSIAESSRKEVLHHVTVMDTMESNDNLERVLS
What is the function of this protein?
Component of the adapter complexes which link clathrin to receptors in coated vesicles (PubMed:10564262).  Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration (PubMed:10564262).  AP19 is probably a subunit of the Golgi membrane adapter (PubMed:10564262).  Component of the AP-1-related (AP-1R) complex, an adapter protein complex that mediates sorting of cargo SNARE SNC1 (PubMed:26658609).  In contrast to the APM1-containing AP-1 complex, AP-1R is incapable of sorting CHS3 (PubMed:26658609).
What are the official names of this protein?
AP-1 complex subunit sigma-1, Clathrin assembly protein complex 1 sigma-1 small chain, Clathrin coat assembly protein AP19, Clathrin coat-associated protein AP19, Golgi adaptor AP-1 19 kDa adaptin, HA1 19 kDa subunit, Sigma1-adaptin.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes small subunit family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasmic vesicle, clathrin-coated vesicle membrane. Endosome. Golgi apparatus.
Protein: YL437_MIMIV
Sequence: MNYNKFELMEFDLNKMVIDPSIVMIAKRGSGKSWIVRDVMYHYRHLPCGVVIAPTDRMNSFYKYFFPDLFIHYEITEAILKNILLRQQMIIDKQKQKKKQGLKIDPSGILIMDDCLSQKKNWSKIQEITEILMNGRHYRLTYVLTMQTPLGLTPDLRLNFDYIFLLKDDTQVNKKKLYNNYAGMFPSQLAFEKVLAKCTEGHKCMVIDNRKPADKIQDKVFWFKARDRKFSFGAREFKDMHKKYYNPEYGRDRYRKLMEGEDVLFGLKKNDTNLKVNLREIPTH
What are the official names of this protein?
Uncharacterized protein L437.
Protein: RS20_STAAB
Sequence: MANIKSAIKRVKTTEKAEARNISQKSAMRTAVKNAKTAVSNNADNKNELVSLAVKLVDKAAQSNLIHSNKADRIKSQLMTANK
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: HIS6_NITWN
Sequence: MFKVRVIPCLDVKDGRVVKGVNFVDLRDAGDPVEAAIAYDAAGADELTFLDITATHENRGIMLDVVRRTAEACFMPVTVGGGVRTIEDIRTLLRSGADKVSINSAAVSRREFVKEASEKFGDQCIVVAIDAKRVSRTGGTDRWEIFTHGGRRSTGIDAIEYAQEVASLGAGEILLTSMDRDGTRQGFDLPLTRRVADSVPVPVIASGGVGNLDHLVDGIREGHATAVLAASIFHFGEFTIRQAKEHMVRAGLAMRLDP
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPO_MYCGE
Sequence: MQTIDVLIVGGGVIGTSCAYELSQYKLKVALLEKNAFLGCETSQANSGVIHSGIDPNPNKLTAKYNILGRKIWIEDWFKKLIFPRKKIATLIVAFNNEEKLQLNLLKERGIKNSIPVENIQILDQQQTLLQEPFINPNVVASLKVEGSWLIDPLIATKCLALASLQNNVAIYSNKKVTKIEIDSDDDFLVFINNETTPQFKTKKLIDAAGHYADWLAETTQVDNFKQTTRKGQYLVLKNQNNLKINTIIFMVPTIHGKGVVVAEMLDGNILVGPNAVEGIEKNKTRSIDLDSINQIKTIGKKMVPSLQFENSIYSFAGSRAIDIETNDFVIRTAKSNPNFIILGGMKSPGLTSSPAIAKRAVELLNLKLKKKINWNPNYNLSWI
What is the function of this protein?
Catalyzes the oxidation of glycerol 3-phosphate to dihydroxyacetone phosphate (DHAP), with a reduction of O2 to H2O2.  The formation of hydrogen peroxide by this enzyme is crucial for cytotoxic effects on host cells.  Does not show any dehydrogenase activity with NAD(+).
What are the official names of this protein?
Glycerol 3-phosphate oxidase, GlpO, L-alpha-glycerophosphate oxidase.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Lipid-anchor.