PharMolix/UniProtQA huggingface dataset:
Protein: RL5_BUCAI
Sequence: MATLYDYYKSKVITQLMHELNYSSVMQVPKIDKITLNMGVGGAASDKKILDNAILDLTAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGQKKWHFFERLIIIAVPRIRDFRGLSSHSFDGQGNYSLGIREQIIFPEIDYDKIDRVRGLDITITTTAKSNHEARLLLSAFNFPFRK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: RNPH_RHILO
Sequence: MRPSKRQFDEMRAISFERGVSKHAEGSCLVKFGDTHVLCTASLEEKVPGWMRNSGKGWVTAEYGMLPRSTGERMRREASAGKQGGRTLEIQRLIGRSLRAVVDLQALGEQQITVDCDVIQADGGTRTASITGGWVALYDCLRWMEARQMASVSKVLKDHVAAISCGIHDGQPVIDLDYLEDSAAGTDANFVMTGKGGIVEIQGTAEGEPFSEDQFAELMGLAKKGIQRLVSLQQMAVA
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: TPS2_DICDI
Sequence: MDIKNLSLKDIKFPKSWETKPSKIEYMQFVYQEAIDMKVWRKDNEIDILTHHHVTDLSRFFWPNADFEGLVLGAELMVWFFAFDDLFDGGFIDDNENEQYRLVNRMNKVFLEGTIEDDSTGAERMGYYLRNKVRAICGEKRQSTFHRFNSSCVQWVDSIIPFIKLKRNQKSLDFNLYIHHRKFNIGAIPCFLVSEIILDPMSNIECFIWLDSRWIKMSEIICEIIALVNDCVSYEKEIKENGAPLNSLKFIQIEKNLNLQESFEYISNYLNELINQYIELETSFIKSYKPITSNYNSNFIAIVEHLHNMSFANVSWSTQTPRYLSQTQPFLELRRNKKIITKIYDLKNK
What is the function of this protein?
Terpene synthase that converts its substrate farnesyl diphosphate (FPP) into the sesquiterpene (3S)-(+)-asterisca-2(9),6-diene (PubMed:27790999, PubMed:27862766).  Is also able to convert geranyl diphosphate (GPP) into a mixture of monoterpenes including (Z)-beta-ocimene, allo-ocimene and linalool (PubMed:27790999).
What are the official names of this protein?
Terpene synthase 2.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: NUOD_NEIG1
Sequence: MANKLRNYTINFGPQHPAAHGVLRMILELDGEQIVRADPHIGLLHRGTEKLAETKTYLQALPYMDRLDYVSMMVNEQAYCLAVEKLAGIDVPIRAQYIRVMFAEVTRILNHLMGIGSHAFDIGAMTAILYAFRDREELMDLYEAVSGARMHAAYFRPGGVYRDLPGFMPKYESSKFRNAKVLKQLNESREGTMLDFIDAFCERFPKNIDTLETLLTDNRIWKQRTVGIGVVSPERAMQKGFTGVMLRGSGVEWDVRKTQPYEVYDKMDFDIPVGVNGDCYDRYLCRMEEMRQSVRIIKQCADWLRVNPGPVITANHKFAPPKRTEMKTGMEDLIHHFKLFTEGMHVPEGETYTAVEHPKGEFGVYIISDGANKPYRLKIRAPGFAHLQGMDEMAKGHMLADVVAIIGTQDIVFGEVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CDK8_HUMAN
Sequence: MDYDFKVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQIEGTGISMSACREIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKREFLTEEEPDDKGDKKNQQQQQGNNHTNGTGHPGNQDSSHTQGPPLKKVRVVPPTTTSGGLIMTSDYQRSNPHAAYPNPGPSTSQPQSSMGYSATSQQPPQYSHQTHRY
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors.  Phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex.  Phosphorylates CCNH leading to down-regulation of the TFIIH complex and transcriptional repression.  Recruited through interaction with MAML1 to hyperphosphorylate the intracellular domain of NOTCH, leading to its degradation.
What are the official names of this protein?
Cyclin-dependent kinase 8, Cell division protein kinase 8, Mediator complex subunit CDK8, Mediator of RNA polymerase II transcription subunit CDK8, Protein kinase K35.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Protein: BPP7C_BOTFO
Sequence: QRWPSPK
What is the function of this protein?
This peptide both inhibits the activity of the angiotensin-converting enzyme (ACE) and enhances the action of bradykinin by inhibiting the peptidases that inactivate it.  It acts as an indirect hypotensive agent.
What are the official names of this protein?
Bradykinin-potentiating peptide 7c, BPP-7c.
What is the protein family that this protein belongs to?
Belongs to the bradykinin-potentiating peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: BCSB1_KOMXY
Sequence: MKMVSLIALLVFATGAQAAPVASKAPAPQPAGSDLPPLPAAASQAATPAAASADQPATTAPAADAASASAADAVVDNAENAIAASDVATVHTYSLKELGAQSALKMQGAATLQGLQFGIPADQLVTSARLIVSGAMSPSLQPDTSAVTITLNEQFIGTLRPDPTHPTFGPLSFDINPIFFITGNRLNFSFASSSKGCTDPSNGLLWASVSEHSELQITTIPLPPRRQLSRLPQPFFDKNVKQKIVIPFVLAQTFDPEVLKATGILASWFGQQTDFRGVTFPVFSTIPQTGNAVVVGVADELPSALGRQAVNGPTLMEVANPSDPNGTVLLVTGRDRDEVITASKGIGFGSSALPTANRMDVAPIDVGARVAYDAPSFIPTNRPVRLGELVPDSALQAQGYAPGALSVPFRVSPDLYTWRDRPYKLNVRFRAPPGPIVDVSRSSLNVGINDTYLEAYPLREPDSTLDQILRRVGLGRGDDSVQKHTMPIPPYRVFGQNQLLFYFEMAAMAEPGCKPGPSTFHMSVDPDSTIDLSNSYHITRMPNLAFMASAGYPFTTYADLSRSAVVLPDHPNGMVVSAYLDLMGFMGATTWYPVSGVDVVSSDHVNDVADRNLIVLSTLANSGDVSQLLSKSSYQISDGRLHMGLRSTLSGVWNLFQDPMSGISNTAPTDVESTLTGGVAAMIEAESPLASGRTVLALLSGDGQGLNNLVQILAQRKNQAKIQGDLVLAHGDDLTSYRSSPLYTVGTVPLWLEPDWYMHNHPSRVIVVGLLGCILIVAVMVRALAKHALRRRRELQEERQRT
What is the function of this protein?
Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP).
What are the official names of this protein?
Cyclic di-GMP-binding protein, CDGBP, Cellulose synthase regulatory subunit, Cellulose synthase protein B.
What is the protein family that this protein belongs to?
Belongs to the AcsB/BcsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type I membrane protein.
Protein: CM3A_CONCT
Sequence: GRCCEGPNGCSSRWCKDHARCC
What is the function of this protein?
Mu-conotoxins block voltage-gated sodium channels (Nav).  This synthetic toxin inhibits tetrodotoxin-resistant and -sensitive voltage-gated sodium channels.  This block is very slowly reversible.  Causes seizures and paralysis, when injected intracranially into mice.
What are the official names of this protein?
Mu-conotoxin CIIIA.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPD_HALOH
Sequence: MINNEVSRKYSSALLEVALESDNLSRFKEELEGISKALKQYDDLKKILYHPRVLPDDKKEVIHQVFSDKVSEPVFNFLNLIVDKRREVYLDFIIRDFIKQANRKEGLVKIEVVSAIELSEKQREQLKNKLKKALNKKIELKTKIDPGIIGGIIIKIGDRLIDGSIKHQLDSIKESIEKIPVTELGVIQNES
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: YOY8_CAEEL
Sequence: MPLPIYKHVSFFCISKCMDKSRNFQPNEGEEEMKKSWVRHEKLCAQLEACSLDLKQNEAQMTILTATGGELKEKHKKIRGLLDEAKANGQQKELEELSKEIENVETQTRIWLNELHDVHDKRVDIDCQMIRLGSEVKKNETYVQLACIDIERMELRHEIRWKKFLQNNPCK
What are the official names of this protein?
Uncharacterized protein ZK652.8.
Protein: ISCS_ECO24
Sequence: MKLPIYLDYSATTPVDPRVAEKMMQFMTMDGTFGNPASRSHRFGWQAEEAVDIARNQIADLVGADPREIVFTSGATESDNLAIKGAANFYQKKGKHIITSKTEHKAVLDTCRQLEREGFEVTYLAPQRNGIIDLKELEAAMRDDTILVSIMHVNNEIGVVQDIAAIGEMCRARGIIYHVDATQSVGKLPIDLSQLKVDLMSFSGHKIYGPKGIGALYVRRKPRVRIEAQMHGGGHERGMRSGTLPVHQIVGMGEAYRIAKEEMATEMERLRGLRNRLWNGIKDIEEVYLNGDLEHGAPNILNVSFNYVEGESLIMALKDLAVSSGSACTSASLEPSYVLRALGLNDELAHSSIRFSLGRFTTEEEIDYTIELVRKSIGRLRDLSPLWEMYKQGVDLNSIEWAHH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur and selenium atoms from cysteine and selenocysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.  Also functions as a selenium delivery protein in the pathway for the biosynthesis of selenophosphate.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABA_ECOSE
Sequence: MVDKRESYTKEDLLASGRGELFGTKGPQLPAPNMLMMDRVVKMTETGGNFDKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEGKGRALGVGEVKFTGQVLPTAKKVTYRIHFKRIVNRRLIMGLADGEVLVDGRLIYTASDLKVGLFQDTSAF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UROK_RABIT
Sequence: MRVLLVCLLLCALVVSDSEGSHELHGVSDASNCGCLNGGTCVTYKYFSNIWRCNCPKKFQGEHCEIDTLKTCYHGDGHSYRGKANTDIMDRPCLAWNSANVLTKTYHAHRPDALQLGLGKHNYCRNPDHQRRPWCYVQVGLKQLIQECKVHDCSSGKKPALPPGKLEFQCGQKALRPRFKIIGGEFTIIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVVSATHCFINHQKKEDYIVYLGRSRLNSMTPGEMKFEVEQLILHEGYRADTLAHHNDIALLKILSNNGQCAQPSRSIQTICLPPWNADPNFGTSCEITGFGKENSTDYLYPEQLKMTVVKLVSYQECQQPHYYGSEVTTKMLCAADPQWETDSCQGDSGGPLVCSVQGRMTLTGIVSWGRGCALKNKPGVYTRVSRFLPWIRSHIGEENGLAL
What is the function of this protein?
Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin.
What are the official names of this protein?
Urokinase-type plasminogen activator, U-plasminogen activator, uPA.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: CSM2_METJA
Sequence: MSKIGKCILNPNEINLILNINSQNANEIIDIAENLAKEFEQIPATKMRDFYDYVLRIDEKNENWYKELVLLKPKLAYNYGKETNRRKKEALEKLAGTFSEIIDKIDNDLNKFKNFKTFFEALVAYHKIYAKSQ
What is the function of this protein?
This subunit may be involved in monitoring complementarity of crRNA and target RNA.
What are the official names of this protein?
CRISPR system Cms protein Csm2, CRISPR type III A-associated protein Csm2.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated Csm2 family.
Protein: ALG11_DICDI
Sequence: MDELIMMVFVLFTIVLLLTVSMTLAALISTIVVLVVPLIICIIALLIALRIKYGSKKDLSEVSIGFFHPYCTAGGGGERVLWCAIKSIQEEYPYVRCVVYTGDKESDDEIFNKVKKTFDIELGRDNLEFIRLKKRKWVEASTYPRFTLIGQSLGSMILGWEALTKFVPTIFLDSMGYAFTFPIFSLIGGSTVACYVHYPTISSDMISSVKSSSYSFNNDVSISSNKFKTISKLIYYNIFSKIYQIVGSFSKLVMVNGTWTGNHIRDIWKKQFGYDLFIVYPPVDVKGRKQLKLGWMDGTRKNMILSIAQFRPEKNHQLQLRTLAHLLEKYPSHREQPLNTKLVLVGGVRDQADRDRVEQLRNLSKELNIEDHVEFQIGISSDQLNQLLSEASVGIHTMYNEHFGIGVVELMAAGVIPVANNSAGPKEDIVRHEDTGFLASTIQEYAEYIHEILAYREKYVEMQKKARDSTDRFSESNFSNQFLKYIKPLINQSLRNNNSSSKKRN
What are the official names of this protein?
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase, Asparagine-linked glycosylation protein 11 homolog, Glycolipid 2-alpha-mannosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PARG_BOVIN
Sequence: MSAGPGCEPCTKRPRWDAAATSPPAASDARSFPGRQRRVLDSKDAPVQFRVPPSSSGCALGRAGQHRGSATSLVFKQKTITSWMDTKGIKTVESESLHSKENNNTREESMMSSVQKDNFYQHNMEKLENVSQLGFDKSPVEKGTQYLKQHQTAAMCKWQNEGPHSERLLESEPPAVTLVPEQFSNANVDQSSPKDDHSDTNSEESRDNQQFLTHVKLANAKQTMEDEQGREARSHQKCGKACHPAEACAGCQQEETDVVSESPLSDTGSEDVGTGLKNANRLNRQESSLGNSPPFEKESEPESPMDVDNSKNSCQDSEADEETSPGFDEQEDSSSAQTANKPSRFQPREADTELRKRSSAKGGEIRLHFQFEGGESRAGMNDVNAKRPGSTSSLNVECRNSKQHGRKDSKITDHFMRVPKAEDKRKEQCEMKHQRTERKIPKYIPPHLSPDKKWLGTPIEEMRRMPRCGIRLPPLRPSANHTVTIRVDLLRIGEVPKPFPTHFKDLWDNKHVKMPCSEQNLYPVEDENGERAAGSRWELIQTALLNRLTRPQNLKDAILKYNVAYSKKWDFTALIDFWDKVLEEAEAQHLYQSILPDMVKIALCLPNICTQPIPLLKQKMNHSITMSQEQIASLLANAFFCTFPRRNAKMKSEYSSYPDINFNRLFEGRSSRKPEKLKTLFCYFRRVTEKKPTGLVTFTRQSLEDFPEWERCEKLLTRLHVTYEGTIEGNGQGMLQVDFANRFVGGGVTSAGLVQEEIRFLINPELIVSRLFTEVLDHNECLIITGTEQYSEYTGYAETYRWARSHEDRSERDDWQRRTTEIVAIDALHFRRYLDQFVPEKIRRELNKAYCGFLRPGVSSENLSAVATGNWGCGAFGGDARLKALIQILAAAVAERDVVYFTFGDSELMRDIYSMHTFLTERKLTVGEVYKLLLRYYNEECRNCSTPGPDIKLYPFIYHAVESCTQTTNQPGQRTGA
What is the function of this protein?
Poly(ADP-ribose) glycohydrolase that degrades poly(ADP-ribose) by hydrolyzing the ribose-ribose bonds present in poly(ADP-ribose) (PubMed:15658938).  PARG acts both as an endo- and exoglycosidase, releasing poly(ADP-ribose) of different length as well as ADP-ribose monomers.  It is however unable to cleave the ester bond between the terminal ADP-ribose and ADP-ribosylated residues, leaving proteins that are mono-ADP-ribosylated.  Poly(ADP-ribose) is synthesized after DNA damage is only present transiently and is rapidly degraded by PARG.  Required to prevent detrimental accumulation of poly(ADP-ribose) upon prolonged replicative stress, while it is not required for recovery from transient replicative stress.  Responsible for the prevalence of mono-ADP-ribosylated proteins in cells, thanks to its ability to degrade poly(ADP-ribose) without cleaving the terminal protein-ribose bond.  Required for retinoid acid-dependent gene transactivation, probably by removing poly(ADP-ribose) from histone demethylase KDM4D, allowing chromatin derepression at RAR-dependent gene promoters.  Involved in the synthesis of ATP in the nucleus, together with PARP1, NMNAT1 and NUDT5.  Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming (By similarity).
What are the official names of this protein?
Poly(ADP-ribose) glycohydrolase.
What is the protein family that this protein belongs to?
Belongs to the poly(ADP-ribose) glycohydrolase family.
What are the subcellular locations of this protein?
Nucleus. Note=Colocalizes with PCNA at replication foci. Relocalizes to the cytoplasm in response to DNA damage (By similarity).
Protein: SYGB_RHOCS
Sequence: MAELLIELFMEEIPARMQVRAGEDFRRLVTDRLAAAGIQFQRAEVHTTPRRIALVVEGIPARQADVREERKGPRVGSPEQALQGFLRAAGLTDISQAEQRDTGKGVFYFAVIEKPGGATIDALPALIDGAIRDLPWPKSMRWGTNQFRWVRPLHGILALFDGQVVPGGLTIGTAEPPPETSEGNACLAGEATARVIRYGNETKGHRFLSPDTLTVTSFEDYKAKLRGAHVILDREERKQLILAGARAAAEAEGLVLKDDPGLLEEVAGLVEWPVVLVGGIDEQFMDVPAEVLTTSMRTHQRYFALETTQGKLAPRFVVVANRPTVDGGAAVVAGNERVLRARLSDAKFFWDQDLATPLETRRQALADIKFHEKLGTMLERAERIEALAVEIARTLGLDTGALERVRIAARLCKADLVTGVVGEFPEVQGILGGHVARAQDLPADVADAIADHYRPLGPSDRVPADPVAVAVALADKIDTLVAFFAIDEKPTGSRDPFALRRAALGVIRLIVENGLRASLLPLFGRAAVAVPAAAGETVGGDLLSFFADRLKVALKEKGVRHDLIDAVFGLGGQDDLVLLLKRVDALAGFVASEDGANLLVAYRRAANILRIEEKKDGVSYSGGGIDAGRLEQAEERALAAALDATAADLAPLLAAEDFTGAMRLLSALRGPVDAFFDKVTVNAPDAVLRANRLRLLARIRDTLNGVADFSRIEG
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIM_DESVV
Sequence: MFSTGTVWKNVAAVRQRAPIIHSITNFVVMNTTANALLAAGASPIMAHAPEEMAEMAGIASALVLNIGTLTKPWVESMMLAGMAARERRLPVVLDPVGAGASSLRTTTALEILEKVRPAVVRGNGSEILALAGAAGDTRGVDSARTAHEAVDGARALARRYGAVVVVSGAEDVVTDGDALWLVRGGSPLMPRVTGMGCTATVLVAAHVAVAADVLEGAVTGMAAMSAAGALAARRSQGPGSFQVAFLDVLHSLDLVTVRDEVEVVRA
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: RIMM_MYCGI
Sequence: MDLVVGRVAKAHGVTGELTVEVRTDDPQGRFVRGAVLRGRPPRGGAEREYVIESVRTHGDRLLVRFDGVADRDAADALRGTVFLVDSADLPPIEDPDEFYDHQLEGLTVITTSGGEVGKVAEVLHTAAGELLAVRTADDTEVLVPFVSAIVLSVSLDDQLITIDPPDGLLELD
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_MYCTA
Sequence: MTERTLVLIKPDGIERQLIGEIISRIERKGLTIAALQLRTVSAELASQHYAEHEGKPFFGSLLEFITSGPVVAAIVEGTRAIAAVRQLAGGTDPVQAAAPGTIRGDFALETQFNLVHGSDSAESAQREIALWFPGA
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KLF14_PANTR
Sequence: MSAAVACLDYFAAECLVSMSAGAVVHRRPPDPEGAGGAAGSEVGAAPPESALPGPGPPGPASVPPLPQVPAPSPGAGGAAPHLLAASVWADLRGSSGEGSWENSGEAPRASSGFSDPIPCSVQTPCSELAPASGAAAVCAPESSSDAPAVPSAPAAPGAPAASGGFSGGALGAGPAPAADQVPRRRPVTPAAKRHQCPFPGCTKAYYKSSHLKSHQRTHTGERPFSCDWLDCDKKFTRSDELARHYRTHTGEKRFSCPLCPKQFSRSDHLTKHARRHPTYHPDMIEYRGRRRTPRIDPPLTSEVESSASGSGPGPAPSFTTCL
What are the official names of this protein?
Krueppel-like factor 14.
What is the protein family that this protein belongs to?
Belongs to the Sp1 C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL14_HELPY
Sequence: MIQSFTRLNVADNSGAKEIMCIKVLGGSHKRYASVGSVIVASVKKAIPNGKVKRGQVVKAVVVRTKKEIQRKNGSLVRFDDNAAVILDAKKDPVGTRIFGPVSREVRYANFMKIISLAPEVV
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RNH2_STAS1
Sequence: MSETIKDIKSKLQHMLSISELERSEYNNDARKGVQNAMIQRRKQLEKEQVLLDNYVKMTEFENSILAENPDALICGIDEVGRGPLAGPVVTCAVILNKNHHFTGLNDSKKLSAKQRHSIESKLLNDVYAYAYGYASVEEIDEINIYEATKLAMHRAIEGLRIKPTHLLVDAMTLDIDIPQTSLIKGDAKSVSIAAASVLAKEHRDQYMRDLGRKYPGYSFENNVGYGTQQHLDGIKKYGILNEHRKTFEPIKSLVN
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PATM2_SOLTU
Sequence: MATTKSFLILFFMILATTSSTCAKLEKMVTVLSIDGGGIKGIIPAIILEFLEGQLQEVDNNKDARLADYFDVIGGTSTGGLLTAMITTPNENNRPFAAAKDIVPFYFEHGPHIFNYSGSIIGPMYDGKYLLQVLQEKLGETRVHQALTEVAISSFDIKTNKPVIFTKSNLAKSPELDAKMYDICYSTAAAPIYFPPHYFITHTSNGDIYEFNLVDGGVATVGDPALLSLSVATRLAQEDPAFSSIKSLDYKQMLLLSLGTGTNSEFDKTYTAQEAAKWGPLRWMLAIQQMTNAASSYMTDYYISTVFQARHSQNNYLRVQENALTGTTTEMDDASEANMELLVQVGETLLKKPVSKDSPETYEEALKRFAKLLSDRKKLRANKASY
What is the function of this protein?
Probable lipolytic acyl hydrolase (LAH), an activity which is thought to be involved in the response of tubers to pathogens.
What are the official names of this protein?
Patatin group M-2.
What is the protein family that this protein belongs to?
Belongs to the patatin family.
What are the subcellular locations of this protein?
Vacuole.
Protein: TATB_PHOLL
Sequence: MFDIGFGELLLVMVIGLVVLGPERLPVAVKTVAGWIRALRSLAANVQNELVQELKLQELQESLKKVQEEAGLQNLSPELKASMDELKEAAESLKKAYQNEPDAGSMKASEINEVAQKPAASQVVASSGPSALVDDQAASATKKKTSD
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: FLOA_STAES
Sequence: MFSIGFIIIAVIIVVALLILFSFVPVGLWISALAAGVHVGIGTLVGMRLRRVSPRKVIAPLIKAHKAGLNLTTNQLESHYLAGGNVDRVVDANIAAQRADIDLPFERGAAIDLAGRDVLEAVQMSVNPKVIETPFIAGVAMNGIEVKAKARITVRANIARLVGGAGEETIIARVGEGIVSTIGSSEHHTEVLENPDNISKTVLSKGLDSGTAFEILSIDIADVDISKNIGADLQTEQALADKNIAQAKAEERRAMAVASEQEMKARVQEMRAKVVEAESEVPLAMAEALRSGNIGVKDYYNLKNIEADTGMRNAINKRTDQNDDESPQQ
What is the function of this protein?
Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts.  FMMs are highly dynamic and increase in number as cells age.  Flotillins are thought to be important factors in membrane fluidity.
What are the official names of this protein?
Flotillin-like protein FloA.
What is the protein family that this protein belongs to?
Belongs to the flotillin-like FloA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Membrane raft; Multi-pass membrane protein.