PharMolix/UniProtQA huggingface dataset:
Protein: 236L_IIV6
Sequence: MKKTRRSSFSGVLMFCKSLFRRFSGVTDVNIVIKIIFYGIYVLLERRSVVEGRPNKRRCPFGTDTFLRCNFRY
What are the official names of this protein?
Uncharacterized protein 236L.
Protein: SECA_FRATF
Sequence: MLSLVQKIIGSRNERFIKKVSRIVQKINSLEPEFEKLSDEQLKAKTFEYRERLANGEILDNLLPEAFATVREAGKRTKNMRHYDVQLIGGIVLHQGKVAEMKTGEGKTLVATLPAYLNALTGDGVHVITVNDYLAKRDAELMSDIYEFLGMSVGVIVADLNPQQRKEAYACDITYGTNNEFGFDYLRDNMAYEKEQQVQRSRNYVIIDEVDSILIDEARTPLIISGASDDSSEMYNLFNRLVPYLEKQEKEEVENEQEQRDFYVDEKSKNAYLTEKGYAKIENMLKKEGILEEDDNLYSPHNITKMHYLNACLRAHSLYQLNIDYIVRDQEIVIIDESTGRAMPGRRWSDGLHQAIEAKEGVKINAENQTMASITFQNFFKLYNKIAGMTGTADTEAFELHSIYGLEVIIIPTNKPMIRKDHHDEIYGSVREKFDAIVEDIKERISKGQPVLVGTASIEASEVLSTLLKKKKIRHNVLNAKQHEKEASIIAMAGYPDNVTIATNMAGRGTDIILGGNLEVEIAQLEDPTPEDIAQIKAEWLKRNEAVKKAGGLCIIGSERHDSRRIDNQLRGRAARQGDPGESKFYLSMDDNLLRIFASQSMAERVKKGLKGGESLAFGFMSKVISKAQGKVESYHFDIRKNLLEYDNVVNTQRKVIYEQRQSFLEAEDVSDILADIRIDVAEQLFHDYVSAGSMHELWDLEGLEKALKSDFMIELDLQKLYEEDDSLGEEDLKRLVREAIEIEFVEKTKNLDSGAVRQFEKFSLLQSLDTHWREHLSSIDHLRNSINLRGYAQKDPKNEYKKEAFELFSTMLDNFKYEVISSLAKIRIATEEETQRAQQEWQESMSDIKAEHESVIDNNQRHDEDEQEEAPKVQQVRREGPKVKRNDPCPCGSGKKYKQCHGKVE
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: DF288_ARATH
Sequence: MSNLRLTIAVFLAALFQTLWWKPRGKRPQSNFHAKRIRTVLQTLLVMLCTDYRCDKGLCKCHGFGGEKENPTAAPLTA
What are the official names of this protein?
Putative defensin-like protein 288.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: LACB_STAAN
Sequence: MKIALGCDHIVTDTKMRVSEFLKSKGHEVIDVGTYDFTRTHYPIFGKKVGEQVVSGNADLGVCICGTGVGINNAVNKVPGVRSALVRDMTSALYAKEELNANVIGFGGRIIGELLMCDIIDAFINAEYKATEENKKLIAKIKHLETSNADQADPHFFDEFLEKWDRGEYHD
What are the official names of this protein?
Galactose-6-phosphate isomerase subunit LacB.
What is the protein family that this protein belongs to?
Belongs to the LacAB/RpiB family.
Protein: RFTRM_RICFE
Sequence: MQYSIKQVLSKASDKLNKIGISSSQLEARILLRYVINKPIEYLLINLDEQLNEVEIEAFEKLLERRLKHEPIAYIIGIKEFYSREFIVNKHVLIPRADTEVLVDVCVHKSSLRATKRSVAISGILSKIASSTPMASSRNDEYTKILELGTGSGCIAISLLCELPNARVVATDISLDAIEVARNNALKYHVTDRIQIIHSNWFENLGKQKFDVIVSNPPYISTDEKPEMALETLNHEPYIALFAEEDGLQAYRIIAENAKKFLKPNGKIVLEIGFKQEEAVTQIFLSNGYNIESVYKDLQGHSRVILFSPINLNRSYARRIGKSLSGLQQNLLDNELPKYLFSKEKLIDEKRKIFLEIGFGMGEHFINQAKMNPDALFIGVEVYLNGVANVLKLASEQNITNFLLFPNNLDFILNDLPNNSLDGIYILFPDPWIKNKQKKKRIFNKERLKILQDKLKDNGNLVFASDIENYFYEAIELIEQNSNFKIMNKNNYLKPHDNYVITKYHQKAIKANRIPRFIILQHVSGDH
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
Bifunctional methyltransferase.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
Protein: GLYA_CROS8
Sequence: MLKREMNIADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGGCEYVDIVEQLAIDRAKELFGADYANVQPHSGSQANFAVYTALLQPGDTVLGMNLAQGGHLTHGSPVNFSGKLYNIIPYGIDESGKIDYEDMAKQAKEHKPKMIIGGFSAYSGIVDWAKMREIADSIGAYLFVDMAHVAGLIAAGVYPNPVPHAHVVTTTTHKTLAGPRGGLILAKGGSEELYKKLNSAVFPSAQGGPLMHVIAAKAVALKEAMEPEFKTYQQQVAKNAKAMVEVFLNRGYKVVSGGTENHLFLLDLVDKNLTGKEADAALGRANITVNKNSVPNDPKSPFVTSGIRIGSPAVTRRGFKEAEVKELAGWMCDILDNINDEAVIERVKGKVLDICARFPVYA
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTH_PROMT
Sequence: MLSDELKLLVGLGNPGTEYEKTRHNVGFMVLEEIARKNNCSFRESKKLFGRTCEYGSGIEKTRLLMPNTYMNESGKSVRSAKDWFDFQNNQLIVLVDDMDLPLGKIRVRSKGSSGGHNGLKSIINHLGTAEFKRLKIGIGAPSNDQQERKSKTVSHVLGRFSKEEFIILNFIIQEIISCIESITSNNWEKISTRLNSYKPDN
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PED1A_MOUSE
Sequence: MVFCLENEMPHRLLGSAMVHFHASEVQQLLHNKFVVILGDSIQRAVYKDLVLLLQKDTLLTASQLKAKGELSFEQDQLVAGGQLGELHNGTQYREVRQFCSGSGHHLVRFYFLTRVYSEYLEDILEELSYGPAPDLVIINSCLWDLSRYGRCSMESYRENLERVFVRMDQVLPDSCLLVWNLAMPLGERVTGGFLLPELQPLAVSLRQDVVEGNFYSATLAGKHCFDVLDLHFHFRHAVRHRHRDGVHWDQHAHRHLSHLLLAHVADAWGVELPKHDRLPDPWIEDWSEMDHSFQGSHKQPPDFREKLALPLLPPFHLPPPMSFPYPLEPSPPPLFPPLPQDTPFFQGQPFPPYEFKYNAMEDFSMPGCGPGMNFVPGPLPPSVSGPVSHGQHRGPVVHRGKPRCVLNNPYHVPRIGGPCRHRLRHSDRLIHTYKQDRRGHAHSGTWPG
What are the official names of this protein?
PC-esterase domain-containing protein 1A, Protein FAM113A.
What is the protein family that this protein belongs to?
Belongs to the PC-esterase family.
Protein: CAPSD_ICRSV
Sequence: MSFDYTDPTFRNYPFPHYCDFDRHQHCDHDLRTNPPPTEPPSRKSKLMSTSENKGKQPLHPPPTEGFPKPPPPPSSTPTTPTPPDQTKAPEPIEKRIIHAFHAEPKTHTNGEAPPAFNPNNMNAVPLNLLNINLKYSPVTNSIANPKQTEAIGKAWVRILQIDPANVFLYAIDLARACADAGSSPEADIIGANEDLNPVVERNALAGVVRDFCPLRAFCAYYSRVVWNLMIKADQPPANWMKSGIDEGAKFAAFDFFHGVLSPASLYVPLERHPTAAERIANQAMFAVKIANAPGNGSELTMDHVAFTKGRITADSKPRPTPFNT
What is the function of this protein?
Required for genome encapsidation.  Forms ribonucleoprotein complexes along with TGB1 helicase and viral RNA (By similarity).
What are the official names of this protein?
Capsid protein, CP, Coat protein.
What is the protein family that this protein belongs to?
Belongs to the potexviruses coat protein family.
What are the subcellular locations of this protein?
Virion.
Protein: Y1895_CHRSD
Sequence: MRRPQLLDRRWLTIILRSLRELIQRFDAHDGLKTASALTYTTLFAVVPFMTVLYAMLSAIPSFQGISEQLQALIFSQFVPATGSALVEHLRDFSRQARSLTLIGLMFLLVTAVMMMVTVERAFNNIWHVSRSRRGVSSFLLYWAVLTLGPLLLGSGFLLSSYLASLTLVRGAAEVLGGPVAFLRLLPLTLSFTAFVFIYMAVPNCRVRFRHAVAGAGLAALALELAKGAFSLYVTYFPSYQVIYGTFAAVPLFLVWVFLSWAIVLVGAELAAWLGERRRAEWRYWAPFWQALGVVSHLYDAHRRGQAVYDRELAMRLGARYSDVMAPLQTLGVAVQLDNDRWMLGRDLGALSLWDFQRAMPWAVPLGESSPAPEMQAIHAALQEAERHRQQVLTQPMEHLLAEGARNDSP
What are the official names of this protein?
UPF0761 membrane protein Csal_1895.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PHM5_PYRSX
Sequence: MAVKSSTVDVRAALQSAGAHYMNLIEFGILKVFIDHQIFDHIPAEGSISVTDLATRTKAEVSLLQRFSDYLVASEVLASPAPHELAHTTRSLSYRSEEIAAGFVSHVYHFFLRPMATWTAYFEENGLREPKDAKTIPLGLATGHPEEDLYGVLDKEPRLAYMFNVAQARSAAIFPMKGLYDFAWLREALEDHIGAESPAIVDIGGSHGLALKELLAENPFIPSKRCAVLDFPQTVEQAQQNLDEDLRDIHFIGGSMLEPLPVALHAAGIYQFRRVLSDFVDKDIILALEQVRRVCAPYSRVLIIEELVKASRDKFAIAQDISVLNFGGKRRSEADWHQLASQAGLQVRHVFEQTETAFAVVELGLA
What is the function of this protein?
Methyltransferase; part of the gene cluster that mediates the biosynthesis of the trans-fused decalin-containing tetramic acid phomasetin, the stereochemical opposite of the HIV-1 integrase inhibitor equisetin (PubMed:29972614).  The PKS module of phm1 together with the enoylreductase phm4 catalyze the formation of the polyketide unit which is then conjugated to L-serine by the condensation domain of the phm1 NRPS module (PubMed:29972614).  Activity of the Dieckmann cyclase domain (RED) of phm1 results in release of the Dieckmann product intermediate (PubMed:29972614).  The Diels-Alderase phm7 then uses the Dieckmann product of phm1 as substrate and catalyzes the Diels-Alder cycloaddition to form the decalin ring of N-desmethylphomasetin (PubMed:29972614, PubMed:34121297).  N-desmethylphomasetin is further methylated to phomasetin by the methyltransferase phm5 (PubMed:29972614).
What are the official names of this protein?
Methyltransferase phm5, Phomasetin biosynthesis cluster protein 5.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.
Protein: CT54_CONSP
Sequence: MRCLPVFVILLLLIASAPSVDAQLKTKDDVPLASFHDNAKGTQHKRIINWCCLVFYQCC
What are the official names of this protein?
Conotoxin Sr5.4.
What is the protein family that this protein belongs to?
Belongs to the conotoxin T superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GATA_RHOP2
Sequence: MTDLTSLTLAEARDGLVNKSFTAVELTDAHLAAIEAARVLNAYVLETPDQARQMAQAADAQIAKGEGGPLAGIPLGIKDLFATKGTRTTACSKILGDFKPPYESTVTSQLWRDGAVLLGKLNNDEFAMGSSNETSCFGPVVNPWRRAGSETKLVPGGSSGGSAAAVAAGLCLGATATDTGGSIRQPAAFTGTVGIKPTYGRCSRWGIVAFASSLDQAGPIARTVRDSAILLGSMAGFDPKDTTSVDRPVPNYEAAIGGSVKGMKIGIPKEYRLDGMPAEIEKLWMQGAEWLKAAGAELVEVSLPHTKYALPAYYIVAPAEASSNLARYDGVRYGTRVNGRNIVEMYENTRAAGFGAEVKRRIMIGTYVLSAGYYDAYYLRAQKVRTLIKRDFEQCFDQGVSAILTPATPSAAFGIGEKGGADPVEMYLNDIFTVTVNMAGLPGIAVPAGSDSQGLPLGLQLIGRPFDEETLFSLGDVIEQSAGRFTPAKWWA
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: THIG_COXB2
Sequence: MWAIGGVQLNSRLLLGTAQYPSPQLMSDAVKAAGVEIITVSLRRQLSPQKENYFWDLLRSLPCHLLPNTAGCSSVKEAVNTARAARELFNTHWIKLEIIGDEYTLQPNPFELVNAATILVKEGFEVFPYCTEDLILCQRLVDAGCRVLMPWAAPIGSGRGLMNTYALQLLRERFPKNILIIDAGLGRPSHAAQVMEMGFDAVLLNSAVALAMDPVVMAAGFAKAVEGGRLGYEGGMIKARNVAKATTPLIGKPFLIEKP
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1957_NATTJ
Sequence: MFHEIVVLLFIFLIALIGKNDLVATAGALLFVMKFSPLSNVFPFLTERGIELGILLLTLSVLTPFAAGDIMPRDLLSTLKSPAGLIAVFSGIVASYLTGHGVELLRSRPEVMVGLIVGSIIGASFLKGVPAGPLVAAGLAAVLIKSLNL
What are the official names of this protein?
UPF0756 membrane protein Nther_1957.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CYB_OECBI
Sequence: MTIMRKTHPLIKIINHSFIDLPTPSNISSWWNFGSLLGICLMVQITTGLFLAMHYTSDTATAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFIHVGRGIYYGSYMLNETWNIGIILLLTTMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITAMVLVHLLFLHETGSNNPSGLNSDSDKIPFHPYYTFKDLLGILLLLMVLMILVLFFPDVLGDPDNYTPANPLNTPAHIXPXXYFLFAYAILRSIPNKLGGVLALLLSILILAAFPLLNSSKQHGLTYRPLTQIIYWIFIANLLILTWIGGQPVEYPFTTIGQIASISYFTIIIILMPIASMIENNILKLHA
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ARI12_ARATH
Sequence: MDNNSVIGSEVDAEADESYVNAALEDGQTGKKSVQRNYATVLTEEDIRALMEIDVQSVSDFTSLSKAEATLLLSHLRWNVDCICKQWSAGAQSVRDSVGLLELDPPSDDNEYFCGACGESHPHKNLASVSCGHRICTRCWTSHINKIISEKPAAEWNLWLKCPVRVGLHASCPASVGLDTIERFASKREKFNYNQYLLRSYVDNRETMKWHPIQGSRCAIDLSPGSGNASVSCHRLVRFCWNCREDAHSPVDCKTAAKWLLENAVPCPKCKLRIPRNQDNSLKMKCLPCNYVFCWFCHVDWIEDMEGTGGDLHFCTFDAVLSDQRGKMSESDSNRYEDCYENWDSNELLMQKEQANLPKLDTIIQELSNTQLENVSQLKFILEAGLQIIECRRVLEWTYVYGYYLREDEVGKQNLLKDTQERLKKFVENLKHCLETNLQPFRYEEEPSKDFNAFRIKLTELTSLTRNHYENVVKDVENGLASVVSEGEASGSGRNQ
What is the function of this protein?
Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates.
What are the official names of this protein?
Probable E3 ubiquitin-protein ligase ARI12, ARIADNE-like protein ARI12, Protein ariadne homolog 12, RING-type E3 ubiquitin transferase ARI12.
What is the protein family that this protein belongs to?
Belongs to the RBR family. Ariadne subfamily.
Protein: NUD17_HUMAN
Sequence: MAEVRVQLLLSRRPESVSFARSVCGLLGAGPGLGTWPIHCSLKRGRLVLSSRPFPGASARLPLQRPPFCPFAALEERPRVPGAELPTDRGVDLGVAVILQSSDKTVLLTRRARTLSVSPNLWVPPGGHVELEEELLDGGLRELWEESGLHLPQGQFSWVPLGLWESAYPPRLSWGLPKYHHIVLYLLVISQESQQQLQARIQPNPNEVSALMWLTPDVAAAVAAAEDGTETPGLLPQDLPPSVLAVELEEDGRARPLVLHMSTLLRMIPTMAEDKERVSTGTKFALKLWLQHLGRTPPPCKSAAYLDPGPAKEEWNMDPLPPNQGSGK
What is the function of this protein?
Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.
What are the official names of this protein?
Nucleoside diphosphate-linked moiety X motif 17, Nudix motif 17.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
Protein: PSAC_LOLPR
Sequence: MSHSVKIYDTCIGCTQCVRACPTDVLEMIPWDGCKAKQIASAPRTEDCVGCKRCESACPTDFLSVRVYLGPETTRSMALSY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: LOLB_FRATO
Sequence: MSKLKIDTKRRFSLLIALVLIISLSSCATTQTNVTAITTKTVFNQETTYHNLLKLKKWQANGFIGIIYDNQAESANYTYLQDGDNFSIKLYGPLGIGSIEIKGDTNSVSLANSKGQKLTAKDAKTLMLEQLGWYVPVEGLKYWIKAIAIPNIRQTSELNTNNLLSKLSQNGWSISYSNYQLVDSKYPLPTKIRMSRDNLTLKIVIKSWQI
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: RL15_MARMM
Sequence: MRLNELRDNDGATKIRTRVGRGIGSGKGKTGGRGVKGQKSRSGVAIKGFEGGQMPLHMRLPKRGFNKPNRKAWAEVNLGRLEKAIAEGKIDAKKPIDADVLIAAGLVRRALDGVRLLAKGELKSKVEITLAGASKAAIAAVEKAGGKVTLTAVADDAAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: PSRP_XANCB
Sequence: MSTIRPVFYVSDGTGITAETIGHSLLTQFSGFNFVTDRMSFIDDADKARDAALRVRAAGERYQVRPVVVNSCVDPQLSMILAESGALMLDVFAPFIEPLERELNAPRHSRVGRAHGMVDFETYHRRINAMNFALSHDDGIALNYDEADVILVAVSRAGKTPTCIYLALHYGIRAANYPLTEEDLESERLPPRLRNYRSKLFGLTIDPERLQQIRQERRANSRYSAAETCRREVATAERMFQMERIPTLSTTNTSIEEISSKVLSTLGLQREMF
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: CDPAS_PYRAR
Sequence: MDLFVFFALIWPPYVANGSAVLASRLKWRHPVDFGHNFVDGRRLFGDGKTYEGLAIGVVLGTVVGYLPNLLHPTLTLLDALILSVAALLGDLLGAFIKRRLCMPRGHPAFPLDQLDFILMAMLVRSLYADVPVEYIIAASVVTPIIHRATNIAAYILRLKKEPW
What is the function of this protein?
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP.  This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
CDP-archaeol synthase, CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-archaeol synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GATC_PSEPF
Sequence: MALERSDVEKIAHLASLGLNDADLPHITSALNSILGLVDEMQAVNTDGIEPLAHPLEASQRLRADVVTESNNREAYQSIAPAVENGLYLVPKVID
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: NPT2B_HUMAN
Sequence: MAPWPELGDAQPNPDKYLEGAAGQQPTAPDKSKETNKTDNTEAPVTKIELLPSYSTATLIDEPTEVDDPWNLPTLQDSGIKWSERDTKGKILCFFQGIGRLILLLGFLYFFVCSLDILSSAFQLVGGKMAGQFFSNSSIMSNPLLGLVIGVLVTVLVQSSSTSTSIVVSMVSSSLLTVRAAIPIIMGANIGTSITNTIVALMQVGDRSEFRRAFAGATVHDFFNWLSVLVLLPVEVATHYLEIITQLIVESFHFKNGEDAPDLLKVITKPFTKLIVQLDKKVISQIAMNDEKAKNKSLVKIWCKTFTNKTQINVTVPSTANCTSPSLCWTDGIQNWTMKNVTYKENIAKCQHIFVNFHLPDLAVGTILLILSLLVLCGCLIMIVKILGSVLKGQVATVIKKTINTDFPFPFAWLTGYLAILVGAGMTFIVQSSSVFTSALTPLIGIGVITIERAYPLTLGSNIGTTTTAILAALASPGNALRSSLQIALCHFFFNISGILLWYPIPFTRLPIRMAKGLGNISAKYRWFAVFYLIIFFFLIPLTVFGLSLAGWRVLVGVGVPVVFIIILVLCLRLLQSRCPRVLPKKLQNWNFLPLWMRSLKPWDAVVSKFTGCFQMRCCCCCRVCCRACCLLCDCPKCCRCSKCCEDLEEAQEGQDVPVKAPETFDNITISREAQGEVPASDSKTECTAL
What is the function of this protein?
Involved in actively transporting phosphate into cells via Na(+) cotransport.
What are the official names of this protein?
Sodium-dependent phosphate transport protein 2B, Sodium-phosphate transport protein 2B, Na(+)-dependent phosphate cotransporter 2B, NaPi3b, Sodium/phosphate cotransporter 2B, Na(+)/Pi cotransporter 2B, NaPi-2b, Solute carrier family 34 member 2.
What is the protein family that this protein belongs to?
Belongs to the SLC34A transporter family.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Note=Localized at the brush border membranes of enterocytes.
Protein: NHAB_CROS8
Sequence: MEISYGRALYRNFLGQSPDWYKLCLLGFLILNPLVFWVSPFTAGWLLVIEFIFTLAMALKCYPLLPGGLLAVEALFIGMTSAEHVREEVANNLAVVLLLIFMVAGIYFMKQLLLLIFTRLLLGIRSKTLLSLAFCFAAAFLSAFLDALTVVAVVISVAVGFYGIYHRVASNRDEGQELVDDAQLDDERRATLERFRAFLRSLMMHAGVGTALGGVMTMVGEPQNLIIAHAAGWSFGDFLLRVAPVSVPVFICGIVTCILVEKTKSFGYGEPLPEPVRKILREYDDKSRQKRTRQDTMKLIIQGLIGVWLITALALHLAEVGLIGLSVIILASSLCGVTDEHAIGKAFTEALPFTALLTVFFAVVAVIIDQHLFAPIIAYVLEASPHNQLSLFYLFNGLLSSISDNVFVGTVYINEAKSALQQGVIDAKQFEMLAVAINTGTNLPSVATPNGQAAFLFLLTSALAPLIRLSYGRMVWMALPYTIVLTLVGLACVQFTLVPFTDWLLQSGWVSTPATTALLH
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaB, Sodium/proton antiporter NhaB.
What is the protein family that this protein belongs to?
Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PHAD2_AMAPH
Sequence: MSDINTTCLPAWLATCPCTGDDVNPTLTCGESLC
What is the function of this protein?
Toxin that belongs to the bicyclic heptapeptides called phallotoxins (PubMed:27978833).  Although structurally related to amatoxins, phallotoxins have a different mode of action, which is the stabilization of F-actin (PubMed:6452160).  Phallotoxins are poisonous when administered parenterally, but not orally because of poor absorption (PubMed:27978833).
What are the official names of this protein?
Phalloidin proprotein.
What is the protein family that this protein belongs to?
Belongs to the MSDIN fungal toxin family.
Protein: ATS12_MOUSE
Sequence: MPCARGSWLAKLSIVAQLINFGAFCHGRQTQPWPVRFPDPRQEHFIKSLPEYHIVSPVQVDAGGHVLSYGLHHPVTSSRKKRAAGGSGDQLYYRISHEEKDLFFNLTVNWEFLSNGYVVEKRYGNLSHVKMVASSGQPCHLRGTVLQQGTTVGIGTAALSACQGLTGFFHLPHGDFFIEPVKKHPLTEEGSYPHVVYRRQSIRAPETKEPICGLKDSLDNSVKQELQREKWERKTLRSRSLSRRSISKERWVETLVVADTKTVEYHGSENVESYILTIMNMVTGLFHSPSIGNLVHIVVVRLILLEEEEQGLKIVHHAEKTLSSFCKWQKSINPKSDLNPVHHDVAVLITRKDICAGVNRPCETLGLSQLSGMCQPHRSCNINEDSGLPLAFTIAHELGHSFGIQHDGKENDCEPVGRHPYIMSQQIQYDPTPLTWSKCSKEYITRFLDRGRGFCLDDIPSKKGLKSNVIAPGVIYDVHHQCQLQYGPNATFCQEVENVCQTLWCSVKGFCRSKLDAAADGTRCGEKKWCMAGKCITVGKKPESIPGGWGRWSPWSHCSRTCGAGAQSAERLCNNPEPKFGGKYCTGERKRYRLCNVHPCRSDTPTFRQMQCSEFDTVPYKNQFYRWFPVFNAAHPCELYCRPIDEQFSERMLEAVIDGTPCFEGGNSRNVCINGICKRVGCDYEIDSNATEDRCGVCLGDGSACQTVKKLFRQKEGSGYVDIGLIPKGARDIRVMEIKAAGNFLAIRSEDPEKYYLNGGFIIQWNGNYKLAGTVFQYDRKGDLEKLIAPGPTNESVWLQLLFQVTNPGIKYEYTVRKDGLDNDVEKLLYFWQFGRWTECSVTCGTGIRRQAAHCVKKGHGIVKTTFCNPETQPSVRQKKCHEKDCPPRWWAGEWEACSTTCGPYGEKKRTVLCIQTMGSDEQALPATDCQHLLKPKALVSCNRDILCPSDWTVGNWSECSVSCGGGVRIRSVTCAKNLNEPCDKTRKPNSRALCGLQQCPFSRRVLKPNKDIAPSGKNQSTAEHDPFKPIPAPTSRPTPLSTPTVPESMSTSTPTINSLGSTIASQEDANGMGWQNNSTQAEEGSHFPTSSGSTSQVPVTSWSLSIQPDDENVSSSAIGPTSEGDFWATTTSDSGLSSSDAMTWQVTPFYSTMTTDPEVEIHSGSGEDSDQPLNKDKSNSVIWNKIGVPEHDAPMETDAELPLGPPPTSYMGEEPSWPPFSTKMEGSLPAWSFKNETPRDDGMIAEKSRKIPLPLAGDHHPATSEKLENHDKLALPNTTNPTQGFGPVLTEEDASNLIAEGFLLNASDYKHLMKDHSPAYWIVGNWSKCSTTCGLGAYWRSVECSSGVDADCTTIQRPDPAKKCHLRPCAGWRVGNWSKCSRNCSGGFKIREVQCMDSLDHHRSLRPFHCQFLAGAPPPLSMSCNLEPCGEWQVEPWSQCSRSCGGGVQERGVSCPGGLCDWTKRPATTVPCNRHLCCHWATGNWELCNTSCGGGSQKRTIHCIPSENSTTEDQDQCLCDHQVKPPEFQTCNQQACRKSADLTCLKDRLSISFCQTLKSMRKCSVPSVRAQCCLSCPQAPSIHTQRQRKQQLLQNHDML
What is the function of this protein?
Metalloprotease that plays a role in the degradation of COMP (By similarity).  Cleaves also alpha-2 macroglobulin and aggregan.  Has anti-tumorigenic properties (By similarity).
What are the official names of this protein?
A disintegrin and metalloproteinase with thrombospondin motifs 12, ADAM-TS 12, ADAM-TS12, ADAMTS-12.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.