PharMolix/UniProtQA huggingface dataset:
Protein: FTSZ_BUCAI
Sequence: MFEPSELSNNAIIKVIGVGGGGSNAVEHMVRERIEGVEFFAINTDAQALRKIEVGQTIQIGNNITKGLGAGANPEIGRTSAEEDKELLKSALDGSDMVFIAAGMGGGTGTGAAPVVAEIAKELGILTVAVVTKPFNFEGKKRMIVAEQGIIELSKYVDSLIIIPNDKLLKVLSRGISLLDAFSAANNVLKGAVQGIAELITRPGLMNVDFADVRTVMLEMGYAMMGTGISSGENRAEEASEIAISSPLLEDIDLSGARGVLVNITAGFDLKLDEFETVGNTIRSFSSDHATVVIGTSLDPDMNDTLRVTVVATGIGMEKNLDVNQIKNKSSREVLMDYRYQYLNISPKKTDKKIIKKEIKNTKEKINKEPEYLDIPSFLRKRAD
What is the function of this protein?
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site.  The regulation of the ring assembly controls the timing and the location of cell division.  One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells.  Binds GTP and shows GTPase activity.
What are the official names of this protein?
Cell division protein FtsZ.
What is the protein family that this protein belongs to?
Belongs to the FtsZ family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane.
Protein: BIOC_GALCS
Sequence: MNEFVIDKKAMRQAFSRAAEGYDASAVLQREVCMRMLERLEYIKLQPARLLDAGSGTGWGGRQLAEKYPAAQVISLDIAIGMLQTSKSRSSWWQKLFGGCRQLPVCADVEALPLAANSLDMVWSNLAVQWCNDLPATFVELHRVLKTEGLLMFSTLGPDTLKELRQAFKGVDERSHLNRFADMHDIGDMLVQAGFAEPVMDMEYLTLTYEDVRGVLQDLKAIGAHNTTAGRGQGLMGKAAWARLLENYEKLRRDGKLPATYEVVYGHAWKPAPRVNRDGAAIIKTSFKIK
What is the function of this protein?
Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM).  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.
What are the official names of this protein?
Malonyl-[acyl-carrier protein] O-methyltransferase, Malonyl-ACP O-methyltransferase, Biotin synthesis protein BioC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: MAZG_ECOLI
Sequence: MNQIDRLLTIMQRLRDPENGCPWDKEQTFATIAPYTLEETYEVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFADSSAENSSEVLARWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCANVGFDWTTLGPVVDKVYEEIDEVMYEARQAVVDQAKLEEEMGDLLFATVNLARHLGTKAEIALQKANEKFERRFREVERIVAARGLEMTGVDLETMEEVWQQVKRQEIDL
What is the function of this protein?
Involved in the regulation of bacterial cell survival under conditions of nutritional stress.  Regulates the type II MazE-MazF toxin-antitoxin (TA) system which mediates programmed cell death (PCD).  This is achieved by lowering the cellular concentration of (p)ppGpp produced by RelA under amino acid starvation, thus protecting the cell from the toxicity of MazF.  Reduction of (p)ppGpp can be achieved by direct degradation of (p)ppGpp or by degradation of NTPs, which are substrates for (p)ppGpp synthesis by RelA.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphohydrolase, NTP-PPase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside triphosphate pyrophosphohydrolase family.
Protein: PYRB_POLSJ
Sequence: MLYRRNPQLNKNGELIHLLSIEGLPKAILTQILDTAANFVSVNNREVKKVPLLRGKSVFNLFFENSTRTRTTFEIAATRLSADVINLDIARSSASKGESLLDTIANLSAMAADLFVVRHGESGAPYLIAQHVAPHVHVINAGDGRHAHPTQGLLDMYTIRHYKKDFSNLTVAIVGDVLHSRVARSDIHALTTLGCPEVRVVGPKTLVPADMAQMGVRVCNTLEEGIKGADVIIMLRLQNERMSGALLPSSQEFFKSFGLTNEKLQLAKPDAIVMHPGPINRGVEIDSAVVDGTQSVILPQVTFGIAVRMAVMGIVAGNEA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: RL5_STAAT
Sequence: MNRLKEKFNTEVTENLMKKFNYSSVMEVPKIDKIVVNMGVGDAVQNSKVLDNAVEELELITGQKPLVTKAKKSIATFRLREGMPIGAKVTLRGERMYEFLDKLISVSLPRVRDFQGVSKKAFDGRGNYTLGVKEQLIFPEIDYDKVSKVRGMDIVIVTTANTDEEARELLANFGMPFRK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: SH_MUMPL
Sequence: MPAIQPLLYLTFLLLILLYLIITLYVWVVSTITYKTAVRHAALYQRSLFRWSLDHSL
What is the function of this protein?
Plays a role in the inhibition of the host NF-kappa-B pathway.  This inhibition occurs at the receptor level, by preventing the signaling of TNFR1 as well as IL-1R and TLR3.
What are the official names of this protein?
Small hydrophobic protein.
What is the protein family that this protein belongs to?
Belongs to the rubulavirus small hydrophobic protein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass membrane protein. Host cell membrane; Single-pass membrane protein.
Protein: Y1830_SULTO
Sequence: MKVLRVRTYIPGFDEILYGGIPERNIVLISGGPGTGKSILGKQFLYNGLVKKDEPGIFVALEEHPVSVIRSFKHFGWDITKYEKEGKFAIVDAFTAGIGSTAQKEKYVVKDVDNVGELSGVLRDAIRNLNAKRVVIDSVSTLYLSKPAMARSIVMQLKRVIAGLGCTAMFISQVSAGERGFGGPGVEHAVDGIVRLDLDEYEGQLYRSVIVWKMRDSKISMVRHPMDITDEGIVIQWDKYLRITNVKAEIQPLPQKEIEEMKKAVEESEEEKESIQEAEIEEE
What are the official names of this protein?
UPF0273 protein STK_18300.
What is the protein family that this protein belongs to?
Belongs to the UPF0273 family.
Protein: COX1_PATPE
Sequence: MQLSRWFFSTNHKDIGTLYLIFGAWAGMAGTAMSVIIRTELAQPGSLLQDDQIYNVIVTAHALVMIFFMVMPIMIGGFGNWLIPLMIGAPDMAFPRMNNMSFWLIPPSFLLLLASAGVESGAGTGWTIYPPLSSGLAHAGGSVDLAIFSLHLAGASSILASINFITTVINMRTPGISFDRLPLFVWSVFVTAFLLLLSLPVLAGAITMLLTDRNVNTTFFDPAGGGDPILFQHLFWFFGHPEVYILILPGFGMISHVIAHYAGKSEPFGYLGMVYAIVSIGILGFLVWAHHMFTVGMDVDTRAYFTAATMIIAVPTGIKVFSWMATLQGSNLRWDTPLLWALGFVFLFTIGGLTGVILANSSIDVILHDTYYVVAHFHYVLSMGAVFAIFAGFTHWFPLFSGVGLHPLWGNIHFTLMFIGVNLTFFPQHFLGLAGMPRRYSDYPDAYTLWNTVSSIGSTISLIATLVFLFILWEAFTSQRTALQPEFSTSSLEWQYSSFPPSHHTFDEIPSTVYLIK
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y754_BACLD
Sequence: MGRKWNNIKEKKASKDANTSRIYAKFGREIYVAAKQGEPDPELNQNLKFVLERAKTYNVPKAIIERAIEKAKGGSEENYDELRYEGFGPNGAMVIVDALTNNVNRTAADVRSTFGKNGGNMGVSGSVAYMFDPTAVIGFEGKTADETLELLMEADIDVRDILEEDDAVIVYAEPDQFHAVQEALQNAGITEFTVAELTMLAQNDVALPEDARAQFEKLIDALEDLEDVQQVYHNVDLGA
What are the official names of this protein?
Probable transcriptional regulatory protein BLi00754/BL02339.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family. YeeN subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_ANADE
Sequence: MTSRRTRARERALQALYQIDVAAEGIDDALSRFWKSFEPVEREVMDLAEGLVRGVAQHRRAVDEAIEAVSTNWRLDRMAKVDRNVLRLAVFELLRTDVPVKVVINEAIELGKKYGSESSGAFVNGVLDKVASGLPPARRGER
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: EBM_ARATH
Sequence: MAEIGKTVLDFGWIAARSTEVDVNGVQLTTTNPPAISSESRWMEAAVPGTVLGTLVKNKAIPDPFYGLENEAITDIADSGRDYYTFWFFTKFQCQRLLNQYVHLNFRAINYSAQVFVNGHKTELPKGMFRRHTLDVTDILHPESNLLALIVHPPDHPGTIPPEGGQGGDHEIGKDVAAQYVQGWDWICPIRDRNTGIWDEVSISVTGPVRIIDPHLVSTFFDDYKRAYLHVTAELENKSTWNTECSVNIQITAELENGVCLVEHLQTENVLIPAQGRIQHTFKPLYFYKPELWWPNGMGKQNLYDILITVVVNEFGESDSWMQPFGFRKIESVIDSVTGGRLFKINGEPIFIRGGNWILSDGLLRLSKERYRTDIKFHADMNMNMIRCWGGGLAERPEFYHFCDIYGLLVWQEFWITGDVDGRGVPVSNPNGPLDHELFLLCARDTVKLLRNHPSLALWVGGNEQVPPKDINEALKQDLRLHSYFETQLLSDKDSDPSVYLDGTRVYIQGSMWDGFADGKGNFTDGPYEIQYPEDFFKDTYYKYGFNPEVGSVGMPVAETIRATMPPEGWTIPLFKKGLDGFIKEVPNRMWDYHKYIPYSNPGKVHDQILMYGTPENLDDFCLKAQLVNYIQYRALFEGWSSQMWTKYTGVLIWKNQNPWTGLRGQFYDHLLDQTASFYGCRSAAEPVHVQLNLASYFVEVVNTTSKELSDVAIEASVWDLDGNCPYYKVFKIVSAPPKKVVKISEFKYPKAANPKHVYFLLLKLYTVSDKAVISRNFYWLHLPGKNYTLLEPYRKKQIPLKITCNAVMVGSRYELEVNVHNTSRANLAKNVVQEDEKRDLGLLQKLFSRCVVSADSNRGLKVVEMKGSDSGVAFFLRFSVHNAETEKQDTRILPVHYSDNYFSLVPGESMSFKISFAAPTGMKKSPRVMLQGWNYPDRFSVFG
What is the function of this protein?
Glycosidase that specifically hydrolyzes the Man-beta-1,4-GlcNAc linkage in the trimannosyl core structure of N-glycans.  Does not hydrolyzes pyridylamino derivatives sugar chains containing Man-alpha-1,3-Man-beta or Xylose-beta-1,2-Man-beta.
What are the official names of this protein?
Mannosylglycoprotein endo-beta-mannosidase, AtEBM, Endo-beta-mannosidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 2 family.
Protein: COA7_XENTR
Sequence: MAGLVDLKNEEEVKEYLDNLGTEYSYQCLKEKQPDGCNRLAEYLENIKKNFESAAQILKINCDQNEHSESCYKLGAYYVTGKGGLPVDLKAAYGCFLKSCNKGGKKSIDSCHNVGLLSHDGRVNDDKPDALKARDYYNKACDGNFAASCFNLSAIYLQGAPGIPKDMNMALHFSEKACSLGHMWGCANASRMYKLGDGVAKNDEKAESLKNKARDLHRMQQERTQQISFGE
What is the function of this protein?
May be required for assembly of mitochondrial respiratory chain complexes.
What are the official names of this protein?
Cytochrome c oxidase assembly factor 7, Beta-lactamase hcp-like protein SELRC1, Sel1 repeat-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the hcp beta-lactamase family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space.
Protein: TR135_RAT
Sequence: MGPIMSTGETSTAHTVLGCQITDKTVITLFVILVFSCLVAVVGNGFIIIALGMKWLLRRTLSAHNKLLISLAASRFCLQCVVIGKNIYVFLNPSSFPYNPVIQLLNLMWDFLTAATIWFCSLLGFFYCVKIATLTHPVFVWLKYRLPGWVPWMLLSAVGMSSLTSILCFIGNHMIYQNYARRGHQPWNATGNSLRHSLEKFYFISIKIIMWTVPTVIFSIFMSLLLVSLVRHMKKTLLALSELRDVWAQAHFKALLPLLSFIILFISCFLTLVLSSASSTPYQEFRYWMWQVVIHLCTVIHPIVILLSNPVLRVVMKRGCC
What is the function of this protein?
Putative taste receptor which may play a role in the perception of bitterness.
What are the official names of this protein?
Taste receptor type 2 member 135, T2R135, T2R35, Taste receptor type 2 member 28, T2R28.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL2_RHOE4
Sequence: MAIRKYKPTTPGRRGSSVSDFAEITRSTPEKSLVRPLHGRGGRNAHGRITTRHKGGGHKRAYRLIDFRRNDKDGIPAKVAHIEYDPNRTANIALLHYADGEKRYIIAPKGLVQGSPVESGAGADIKPGNNLPLRNIPTGTTIHGVELRPGGGAKMARSAGASIQLLGKEGSYATLRMPSGEIRRVDVRCRASVGEVGNAEQSNINWGKAGRMRWKGKRPTVRGVVMNPVDHPHGGGEGKTSGGRHPVSPWGKPEGRTRKNKASDKMIVRRRRTGKNKR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: CYSP_PLAVS
Sequence: MAQDIKIMNLTKSSLEALNRNQMLSKKSSRKILKICMYAILTFAMCGVVLICLTAMSNSDGSLTQSGSHNQSGSLKGLSSTPGDGEILNKAEIETLRFIFSNYPHGNRDPTGDDVEKPADAALPNEEDQKVKIADAGKHIKLMKQYNEIVADMSEDNKEQLAKMLRELLKKKINERKKKREDPNGNNEEGKEVINISVPSFNYKRVSANQDDSDDEEEVSVAQIEGLFVNLKYASKFFNFMNKYKRSYKDINEQMEKYKNFKMNYLKIKKHNETNQMYKMKVNQFSDYSKKDFESYFRKLVPIPDHLKKKYVVPFSSMNNGKGKNVVTSSSGANLLADVPEILDYREKGIVHEPKDQGLCGSCWAFASVGNVECMYAKEHNKTILTLSEQEVVDCSKLNFGCDGGHPFYSFIYAIENGICMGDDYKYKAMDNLFCLNYRCKNKVTLSSVGGVKENELIRALNEVGPVSVNVGVTDDFSFYGGGIFNGTCTEELNHSVLLVGYGQVQSSKIFQEKNAYDDASGVTKKGALSYPSKADDGIQYYWIIKNSWSKFWGENGFMRISRNKEGDNVFCGIGVEVFYPIL
What is the function of this protein?
Probably degrades erythrocyte hemoglobin.
What are the official names of this protein?
Cysteine proteinase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
Protein: CH10_STREI
Sequence: MLKPLGDRVVLKVEEEKEQTVGGFVLAGASKERTQVATVVAVGDGARTLTGELVAPSVAAGDKVIIENGVGIEVKDDDNTVTIVREADILAILA
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_AYWBP
Sequence: MQTKIKKLIAQFHTSLQKNKYDLDKLMILDKEFLGKKGILFELTQELKNLPHAQKSVAGKLINFLKQEIIFTLQKEKETLKRNQLNAKILQEEIDPTLPAFNFCQGSTHPLNQIIEKIEDLFLSLGYEIKEGNEIETLFYNFEMLNMGKGHPAREMQDSFYIDSQKLLRTHTSNIQVKEMKARQGKPLKIISSGKVYRKDDDDATHSHQFMQLEGLVIDKNINFSVLKETLLLITKELFGNSQEIHLRPSYFPFTEPSIEVDLVITKKDGTKEYLEILGAGLVHPQVLKNANYDPEKYQGFAFGIGIERIAMIKYQIENIRYFYANDIRFLKQFARNADNENY
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPND_ECO57
Sequence: MTNFTTSTPHDALFKSFLMHPDTARDFMEIHLPKDLRELCDLDSLKLESASFVDEKLRALHSDILWSVKTREGDGYIYVVIEHQSREDIHMAFRLMRYSMAVMQRHIEHDKRRPLPLVIPMLFYHGSRSPYPWSLCWLDEFADPTTARKLYNAAFPLVDITVVPDDEIVQHRRVALLELIQKHIRQRDLMGLIDQLVVLLVTECANDSQITALLNYILLTGDEERFNEFISELTSRMPQHRERIMTIAERIHNDDCRANS
What is the function of this protein?
A low activity DNA endonuclease probably yielding 3'-hydroxyl ends.  Involved in RecA-independent recombination and horizontal gene transfer (By similarity).
What are the official names of this protein?
Recombination-promoting nuclease RpnD.
What is the protein family that this protein belongs to?
Belongs to the Rpn/YhgA-like nuclease family.
Protein: METB_MYCTU
Sequence: MSEDRTGHQGISGPATRAIHAGYRPDPATGAVNVPIYASSTFAQDGVGGLRGGFEYARTGNPTRAALEASLAAVEEGAFARAFSSGMAATDCALRAMLRPGDHVVIPDDAYGGTFRLIDKVFTRWDVQYTPVRLADLDAVGAAITPRTRLIWVETPTNPLLSIADITAIAELGTDRSAKVLVDNTFASPALQQPLRLGADVVLHSTTKYIGGHSDVVGGALVTNDEELDEEFAFLQNGAGAVPGPFDAYLTMRGLKTLVLRMQRHSENACAVAEFLADHPSVSSVLYPGLPSHPGHEIAARQMRGFGGMVSVRMRAGRRAAQDLCAKTRVFILAESLGGVESLIEHPSAMTHASTAGSQLEVPDDLVRLSVGIEDIADLLGDLEQALG
What is the function of this protein?
Catalyzes the formation of L-cystathionine from O-succinyl-L-homoserine (OSHS) and L-cysteine, via a gamma-replacement reaction (By similarity).  In the absence of thiol, catalyzes gamma-elimination to form 2-oxobutanoate, succinate and ammonia.
What are the official names of this protein?
Cystathionine gamma-synthase, CGS, O-succinylhomoserine (thiol)-lyase.
What is the protein family that this protein belongs to?
Belongs to the trans-sulfuration enzymes family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YAE1_ASPTN
Sequence: MDNSLDDIFGSSPPHETAHPIAPPSNPSPSNPAEPSELPSLRRQHVTAGYRDGISASKGEHVQAGFDAGFPVGAQLGMRAGTVLGILEGVLRGYESRTSSVVKKPARTAAGGATKSENPNEADAEARNAKRAEILTLYQQALKDLDVQAVFAGLQGAEGEKPETQLGRKGDVAVSGWEKRVLVAHWEENMEALEAKDDGEGEGAAEEGEASKAAPAPALS
What is the function of this protein?
The complex LTO1:YAE1 may function as a target specific adapter that probably recruits apo-RPLI1 to the cytosolic iron-sulfur protein assembly (CIA) complex machinery.  May be required for biogenesis of the large ribosomal subunit and initiation of translation.
What are the official names of this protein?
Protein yae1.
What is the protein family that this protein belongs to?
Belongs to the YAE1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: AC18_NPVAC
Sequence: MERLLNQLNLGVLPYITTKDIEDRLRDKIVAKAKLAFIKDCFEAVVCENGGLFVLTGGAAVTCHIDDDRSALKCIDFDYYGFCAKMFCNLQTNLQKCVDQHYAELDVLTRQVYMSDPLVVLKCYQNGAYRLNGQINLHLNRHIKCIKTQYNDEFDLVRFALQIDITSADGVDEYTDNGVKITTAPLSFNVFFVNVRIMKRPFNADRCIKNFSLFGNEYHVLVSSLQRVLNDQLMCLLKDIFTNKFDYKIERRLKHLKRLFANLPAESYNSCVNDHTDMCLYKEQNETITNFVKKILDISGPALGCRKLMHIYLTTDTFSGQLPAYLTHYVNYPHKSLCDQNWKRFMSCIFSLY
What is the function of this protein?
May play a role in occlusion-derived virions (ODV) formation and/or regulation of late viral gene expression.
What are the official names of this protein?
Protein AC18.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=Localizes within the host nucleus few hours after infection while in the late phase of virus infection mainly localizes into the intranuclear ring zone where occlusion-derived virions (ODVs) formation occurs.
Protein: RL32_RHIEC
Sequence: MAVPKRKTSPSKRGMRRSADALKAPTYVEDKNSGELRRPHHIDLKTGMYRGRQVLTPKESA
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: NDK_LISIN
Sequence: MEQTYVMVKPDGVERGLIGEIVAKIEKKGIKLVAGKLMQIDRTLAEQHYAEHIGKPFFEDLIGFITSGPVFAMVLEGDDVIKTARRMMGKTNPLEADPGTIRAEYAIHTNRNVIHGSDSPESAKREIQLFFEPHEILSYEKAVDTWI
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_SYNY3
Sequence: MALSIECQQRPEKVNPRALRREGLIPATLYGHNGAESISLVVDHKTAITMLRSVTVKETPIEVKIPHLSWEGEAVVQEIQCHPWRRNLYHLAFFAGKK
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: MYCOS_MOUSE
Sequence: MVAFFSKATKCGNGHLPADLRFGGAVYLKPSIGPSEAVVQRNSMDKLDFQNIDLVSEINKRRKAMATRDETITKKSGEGEEMLPSMGMDHESPSKAHLMVPPAPPPSPADAADINGFSFKIWEAGTSVNSDFNSWKANVSKFH
What are the official names of this protein?
Myocilin opposite strand protein.
Protein: ATG9_CANAL
Sequence: MSSSSYNPYKNNVNDRLINNSTDSFQDNDQGIPNNNDTFLSRIFGLNSIYNQLQDNYQYYDPEFDSSLNQQLQQSIQENDEAEDESLLPQHQQQQQQAAPMDLSIQDKSAKQKSKSSSLLNSDSDSDLSSSEDSYVRPNIPQIPSTPIETENQGSSSKIKFSIPQRAKNFVGKLHPHHEPTLPVYQTPQEFRRNLPQQQRASATVNTNYQRTRNNNRRFIIPPKERALYLWANITNMDEFLSDVYYYYRGRGLLNIVLSRGFDLIILIFILIFTVFLKWGIDYSIFFDNLHQEESKHITLNDMIIPNYFATIPLSIKFILFGFSVYILLRSVQLYLDYNYKLKELKNFYHYLLDVTDDELMTISWKTIVEKLMLLKDYNSLTSTTKSNNFSENHYVNDLSSKVRLNAHDIANRIMRRENYMIALINKDILDLSVLFMNEKSLLTKTLEWNLKLCIDNFIYNQQGQINGKILKEYNRNQLARELTSRFKLAAIINLILSPFIVIYFVLLYFFRYFNEYKSNPASILGLRQYTPYAEWKLREYNELSHLFNKRLIMSMGPANTYIDQFPKGFLVVNLMRLINFISGSILAVLVIMGILLEDENHSFWSFEITDGRSALFYISIFGTIWAITASSATGTSHESTISTTSQSSNSNSNSNAASTFVYDPEASLRYVAQFTHYLPSSWNKKLHTIQVKNEFCQLYCLKIIIIINEILSSVLTPFILWFKISHNSGNIIDFYREYSIHVDGLGYVCYFAMFNFEEKDKNMMSDLNKSKKRRKRMKNKMNKYGKTKMVNPISGKTVNSEIEMTKISKSESERSSDDESGNEQDYDNDEELDYLSYKKDDKMIKSYMYFLESYGGSKQPQPQPPQQQQHPQNQNQTVGGLRNRNPIQSIDPAIMTGNYYDQQSLNSSIYNINYKFDDSGLLQDETMNSSSRKKGGVLGMLNQFYKQDINR
What is the function of this protein?
Phospholipid scramblase involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation (PubMed:17185534).  Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome.  Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through atg2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.  Required for mitophagy.  Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress.  Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking (By similarity).
What are the official names of this protein?
Autophagy-related protein 9.
What is the protein family that this protein belongs to?
Belongs to the ATG9 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: GLMM_THEVB
Sequence: MLVWREESTMTGQQPIRFGTDGIRGRAGELLTPNLALSLGYWVGEVLRQTTDAPQRPFIIGQDSRNSSDMLATALAAGLTAAGFEVWHVGLCPTPCIAYLTATTEAIGGAMISASHNPPADNGIKIFGSDGSKLCPDLQKEIEAHLNAGRSLPYREDWGHLHHRPELVQRYRHAVQAPLQDRQPLRGLRVVLDLAWGSAVAVTPTVFHALGAEVIALHDRADGNRINVNCGSTYLEPLQQAVREARAAMGFAFDGDADRVLAVDSQGRVVDGDHILYFWGQQLQSQAQLPKDLIVATVMSNLGFERAWQARGGQLVRAAVGDQYVHAEMLRHGAMLGGEQSGHILCRHYGVGGDGLLTAVHLATLVQDSGLSLAQLRDQSFTPYPQILRNVRVEDRQRRLRWQECEPLQRMIAKAQLDMGDRGRVLVRASGTEPVIRVMVEAEQQNIADYWTETLVQTVSAHLAA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.