PharMolix/UniProtQA huggingface dataset:
Protein: CU63_LOCMI
Sequence: GLLGLGYGGYSGYGGYGGYGHGLALAAAPAAIAAPAVVAAPAIAHAPAVAVAPAVAHAPAAVSTVSQVSYGTTHYAPAVAKVAAAPVAVAAPAIAAAPAIAAAPAVGLGYGQGLSLGYGHGLGYGHGLSLGYAAAAPALSLGYGGYGHGLSLGYGHH
What is the function of this protein?
Component of the cuticle of migratory locust which contains more than 100 different structural proteins.
What are the official names of this protein?
Cuticle protein 63, LM-ACP 63, LM-63.
Protein: MUTL_SHEPW
Sequence: MAIEKLPPQLANQIAAGEVVERPASVIKELVENSLDAGATRVDIEIDKGGSKLIRIRDNGFGIPKQDLSLALSRHATSKLKSLDDLEAIMSFGFRGEALASISSVSRLTLTSRTETQAEAWQAKAEGTEMAVQILPAAHPVGTTIEAVDLFFNTPARRRFLKSDKTEFTHIDEWLKRIALVRRDIHFTLKHNGKSVRNYRPAMTEIQYLQRLGQVCGKAFAETCLHISCSHNDLTLSGYLQAPGAASGYCETQYFYVNGRLVKDRLVNHAVRQAFSEYAAGVSPGYVLMLELDPHQVDVNVHPAKHEVRFHQSRYVHDYILQALQSAMAQSSELGLEAQPEPTDESGAAFESNSTNSNVSSTSYSEPNTKPVAVNERPLTTTATSYNQGQSSYRTPLRPATHRADVELPSQSSLEAYASLLSRSSAEPASGKVVSNPHASAVSDASVKMPAVLADKYWVIVEEDSIRLLSIADVIKETARQQIQAKLAQGLVGQPLLMPVAVPVDDNWNEVIETREILLRKLGIELSIRLGQLIIKKVPPYLRDSQLAVLIPELLQWIRFEEPSDDALVHWLTTQASSRFTASAEAWLAFSTLDSSAKSALYNQSQELPWQQWMKESQSD
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: RO60_DEIRA
Sequence: MKNLLRAINPLNRPQTERLDERQVRNNAGGFVYTVSDESRLTRFLVLGVDGGTFYASAQKHTVQATDFVRELVQRDAALALRVTLDVVRGQRAPKADPALLVLALIAKTAPNAADRKAAWDALPEVARTGTMLLHFLAFADALGGWGRLTRRGVANVYETADVDKLALWAVKYKARDGWSQADALRKAHPKTDDAARNAVLKFMVDGVLPKVDSPALRVIEGHLKATEAQTDAAAAALMQEYRLPLEAVPTHVRGAEVYRAAMQTNGLTWLLRNLGNLGRVGVLTPNDSATVQAVIERLTDPAALKRGRIHPLDALKARLVYAQGQGVRGKGTWLPVPRVVDALEEAFTLAFGNVQPANTRHLLALDVSGSMTCGDVAGVPGLTPNMAAAAMSLIALRTEPDALTMGFAEQFRPLGITPRDTLESAMQKAQSMSFGGTDCAQPILWAAQERLDVDTFVVYTDNETWAGQVHPTVALDQYAQKMGRAPKLIVVGLTATEFSIADPQRRDMLDVVGFDAAAPNVMTAFARGEV
What is the function of this protein?
Binds to several small RNAs that accumulate during recovery from UV irradiation (PubMed:17392270).  Contributes to the resistance of D. radiodurans to ultraviolet irradiation (PubMed:10766734).
What are the official names of this protein?
RNA-binding protein RO60, 60 kDa SS-A/Ro ribonucleoprotein homolog, Ro sixty-related protein.
What is the protein family that this protein belongs to?
Belongs to the Ro 60 kDa family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STA10_HUMAN
Sequence: MEKLAASTEPQGPRPVLGRESVQVPDDQDFRSFRSECEAEVGWNLTYSRAGVSVWVQAVEMDRTLHKIKCRMECCDVPAETLYDVLHDIEYRKKWDSNVIETFDIARLTVNADVGYYSWRCPKPLKNRDVITLRSWLPMGADYIIMNYSVKHPKYPPRKDLVRAVSIQTGYLIQSTGPKSCVITYLAQVDPKGSLPKWVVNKSSQFLAPKAMKKMYKACLKYPEWKQKHLPHFKPWLHPEQSPLPSLALSELSVQHADSLENIDESAVAESREERMGGAGGEGSDDDTSLT
What is the function of this protein?
May play metabolic roles in sperm maturation or fertilization (By similarity).  Phospholipid transfer protein that preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl chain (18:1 or 18:2) on the sn-2 position.  Able to transfer phosphatidylcholine (PC) and phosphatidyetanolamline (PE) between membranes.
What are the official names of this protein?
START domain-containing protein 10, StARD10, Antigen NY-CO-28, PCTP-like protein, PCTP-L, Serologically defined colon cancer antigen 28, StAR-related lipid transfer protein 10.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum. Cytoplasm. Membrane. Note=In testis was predominantly detected at the flagella of elongated spermatids, with a strong signal also found at the tail of epididymal sperm (By similarity). Mainly cytosolic.
Protein: SPRTL_STRMU
Sequence: MNLTDYVKEVSRQDFGIEFQHTASWNSRLQTTGGRFFPEDGHLDFNPKFCKKGDAGTFRKIVRHELCHYHLYYAGKGYRHGDKDFKDLLLQVNGVRYAPSIQSNTFYHYYQCESCGQVYQRKRRMNTKKYACGNCHGKLRHQNQS
What are the official names of this protein?
Protein SprT-like.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIE_STRS2
Sequence: MNRKMLQVYFICGTSDCPKGKFLDVLEKALQAGITCFQFREKGEQGLTGADKLLLAKQVQHLCHRYQVPLIINDDVELARAIDADGIHLGQEDLSVVEARQLFPGKIIGLSVGTKEEYLNSPIDLVDYIGSGPVFPTLSKDDASPAIGMDGLKQLRKLNSDIPMVAIGGLSAKDCKEVLQAGADGIAVISAISHAEDPYKATKILVDGMQAMILKFNQVESNKQILKNP
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: NOP2C_ARATH
Sequence: MSKARVLLKPSSLTTCLTRAKAFFSSVSQSRSISHQMEMGPSDSERYCYDPVLRWNPEVEDYFTKAYGPDHFARISKALTRPSSYSCIRVNTVKTTSDAVIEKLTKILNDSEEGLKLVQPDGSSPVTKCQIPGLDYVVFVNGSGPHKIEYDSGLENPPKEVLVSRKCAEAVLRGAQVYVPGVLACTAHVEKGDAVAVCVAMEQPGDEGDWSVNMTRGTTLQGLPTDPYYRERSGLYIGMGTAMLSRAGMFRVPNGIAVDLNHRVFRLPSLHNILEGEIFLQNLPSIIVAHALDPQKGERILDMCAAPGGKTTAIAILMNDEGEIVAADRSHNKVLVVQNLSAEMGFTCITTCKLDALKSVCLPTTLNESTILINGDNSSSMTSHSELSSNEEMTSVTSRRSEADKSCEKNDSTEQPNGGDNVSQAYIRKNKGRLKNGRGRTQCQGGRAGKSQGFPPNSFDRVLLDAPCSALGLRPRLFAGLETVVSLRNHGWYQRKMLDQAVQLVRVGGILVYSTCTINPSENEAVVRYALDKYRFLSLAPQHPRIGGPGLVGRCEFPDGYIEEWLKPGEEELVQKFDPSSELDTIGFFIAKFSVGPKD
What is the function of this protein?
Involved in ribosomal large subunit assembly (By similarity).  S-adenosyl-L-methionine-dependent methyltransferase that may methylates the C(5) position of cytosine in rRNA (By similarity).  May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation (By similarity).  Seems involved in the regulation of cell proliferation (By similarity).
What are the official names of this protein?
rRNA (cytosine-C(5))-methyltransferase NOP2C, Nucleolar protein 2C, tRNA methyltransferase 4f, AtTRM4f.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: NU6M_PAPHA
Sequence: MTYVLFTLSVMLVMGFVGFSSKPSPIYGGLALVVSGVVGCMIILNYGGAYLGLVMFLIYLGGMMVVFGYTAAMAIEEYPETWGSGFEVLACFLVGLMMEVGLVLWVLDFDEVVVMVGFNDMGNWVVFEGEGSGLVRSDSIGAGALYDYGRWLVVVAGWTLFVGVYVVIEITRGN
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: EFG_FRATH
Sequence: MPRNTALEKYRNIGICAHVDAGKTTTTERILFYTGLSHKIGEVHDGAATMDWMEQEQERGITITSAATTTFWSGMDQQFEKHRINIIDTPGHVDFTIEVERSLRVLDGAVVVFCGSSGVEPQSETVWRQANKYGVPRIVFVNKMDRSGADFERVCAQIKTRLKANVVPVQLNIGAEEDFKGVIDLIRMKAIMWNEEDMGLTYELVDIPADLQDRAEELRMEMIEAAAEASEELMEKYLEGGELSEDEIHQGLRARVLNNEIVLAFCGSAFKNKGVQAVLDGVVRYLPAPNQVPAIKCETEDGEPASRPSSDDAPFAALAFKLATDPFVGNLTFIRVYSGVLKSGDAVYNPVKGKKERVGRIVQMHANKRDEIKEVRAGDIAACIGLKDVTTGDTLCDQEDVVILEKMDFPEPVISVAVEPKSKADQEKMSIALGKLAAEDPSFRVKTDEESGQTIISGMGELHLDIIVDRMRREFKVEANVGNPQVAYRETIRSKVEQEAKFVRQSGGRGQYGHVFVRFEPLDEVDENGEAKVFKFVDEVVGGVVPKEYIGSVAKGIEEQLNNGVLAGYPMIGVKATLYDGSYHDVDSSEMAFKIAGSMALKEGAKKANACILEPIMKVEVVTPEDYLGDVMGDLNRRRGIIEGMDENPSGRVINALVPLAEMFGYATNVRSISQGRASFSMEFKKYAEVPNNIADEIIKSRNS
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASIP_FELCA
Sequence: MNILRLLLATLLVCLCLLTAYSHLAPEEKPRDDRNLRSNSSMNMLDLSSVSIVALNKKSKKISRKEAEKKRSSKKKASMKNVAQPRRPRPPPPAPCVATRDSCKPPAPACCDPCASCQCRFFRSSCSCRVLNPTC
What is the function of this protein?
Involved in the regulation of melanogenesis.  The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity).
What are the official names of this protein?
Agouti-signaling protein, ASP, Agouti switch protein.
What are the subcellular locations of this protein?
Secreted.
Protein: Y158_GLAP5
Sequence: MSEIALTVSLLSLVAVIGLWIGHIKVRGVSLGIGGVLFGGILVSHFMTQYGVKLDGHTLHFIQEFGLILFVYTIGIQVGPGFFASLRQSGLKLNAFAVMIVGISGILVILLHKIFDVPLPVILGIFSGAVTNTPSLGAGQQILTELGGESITAVMGMGYAIAYPFGIIGILLAMWLIRIIFKINVDKEADEFDSATNNKKDGLSTMNVRITNPNLNGLMLQEFPDFELHEVVYSRIKRNDELFVPKVHTQIQIGDILHLVGTKTALHKMQLILGEEVNVSLSTKGTMYRTERAVVTNEKVFGKQIRQLMLKGKYDVVISRLNRAGVELVPNGQMTLQFGDVLNLVGRQEDIEAVMAIIGNAQQKLQQVQMLPIFIGVGLGVLLGSIPIYLPGFPVALKLGLAGGPLVVALILARIGSIKKLYWFMPPSANLALREIGIVLFLAVVGWKAGGNFLNTLLSNDGLAWIGYGAIITFVPLIVTGLVARIYGKLNYLSLCGLLAGSMTDPPALAFANGIKEGNGAAALSYATVYPLVMFCRIILPQILAILLWVAG
What are the official names of this protein?
Putative transport protein HAPS_0158.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family. YidE subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRYB2_HUMAN
Sequence: MLNLLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPKKP
What is the function of this protein?
Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type.  May play a role in innate immunity.
What are the official names of this protein?
Tryptase beta-2, Tryptase-2, Tryptase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Tryptase subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Released from the secretory granules upon mast cell activation.
Protein: Y1146_STRPM
Sequence: MTTKKAYMYVLECADKTLYTGYTTDLKKRLATHNAGKGAKYTRYRLPVSLLYYEVFDSKEAAMSAEALFKKRKTRSQKLAYIATHQKEKKNH
What are the official names of this protein?
UPF0213 protein M28_Spy1146.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: RLMH_NITHX
Sequence: MRLVVIAIGRLKQGPERELADRYRGRFDDIGRKLGFRGFDVHEIPESRARDAKQRIREEAAAILALAPEGAVLVALDEKGKNIDSAAFADHLGRWRDESVTSTVFAVGGADGLSPELRRKARLSVAFGAATWPHQIVRVMLLEQIYRAATILAGHPYHRG
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3386_BACCZ
Sequence: MPIWLGILVGVVALVAGVALGFFIARKYMMNYLQKNPPINEQMLKMMMMQMGQKPSQKKINQMMSAMNKQQMK
What are the official names of this protein?
UPF0154 protein BCE33L3386.
What is the protein family that this protein belongs to?
Belongs to the UPF0154 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: NGFV_CRYNI
Sequence: MSMLCYTLIIAFLIGIWAAPKSEDNVPLGSPTTSDLSDTSCAQTHEGLKTSRNTDQRHLAPKKAEDQELGSAANIIVDPKLFQKRRFQSPRVLFSTQPPPLSRDEQSVEFLDNEDTLNRNIRTKRETHPVHNLGEHSVCDSISVWVTNKTKATDIKDNMVTVMVDINLNNEVYKQYFFETKCRNPNPVPSGCRGTDSRHWNSYCTTTQTFVKALTMEGNRASWRFIRIDTACVCVISRKTDNF
What is the function of this protein?
Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems.  It stimulates division and differentiation of sympathetic and embryonic sensory neurons as well as basal forebrain cholinergic neurons in the brain.  Its relevance in the snake venom is not clear.  However, it has been shown to inhibit metalloproteinase-dependent proteolysis of platelet glycoprotein Ib alpha, suggesting a metalloproteinase inhibition to prevent metalloprotease autodigestion and/or protection against prey proteases (By similarity).  Binds a lipid between the two protein chains in the homodimer.  The lipid-bound form promotes histamine relase from mouse mast cells, contrary to the lipid-free form (By similarity).
What are the official names of this protein?
Venom nerve growth factor, v-NGF, vNGF.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: TFE_SULIL
Sequence: MVNAEDLFINLAKSLLGDDVIDVLRVLLEKGTEMTDEEIANQLNIKVNDVRKKLNLLEEQGFVSYRKTRDKDSGWFIYYWKPNIDQINEILLNRKRLILDKLKSRLEYEKNNTFFICPQDNSRYSFEEAFENEFKCLKCGSQLTYYDTEKIKSFLEQKIRQIEEEIDKETKLGANKSH
What is the function of this protein?
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase.  Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment.  Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal.  It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes.  Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
What are the official names of this protein?
Transcription factor E, TFE, TFIIE subunit alpha homolog, Transcription initiation factor TFIIE.
What is the protein family that this protein belongs to?
Belongs to the TFE family.
Protein: RADA_PYRAR
Sequence: MSSKKKKTDAEAAQVQAAVEVSPDLDVEELEGVGKVTGAKLKEKGFYTVKDVAFASVKELAEIIGNEERALQIIESARKMLGLHSFISALEVYERRKKIRRISTGVRSLDELLGGGIETRAVTEVVGEFGSGKTQLCHQLAVMVQLPEERGGLGAKAIYIDTENTFRPERIMQMARARGLDPDQALNNIFYARAYSSDHQMILVEHAKSIVKQHNVALIVVDSVIAHFRSEFPGRENLAERQQKLNKHVADLLRLADAYDVAVVITNQVMAQPDVFFGNPLRPAGGNILAHGATYRLWLRKSKENIRIVKIFDSPYHPEGEVSFRITEEGLID
What is the function of this protein?
Involved in DNA repair and in homologous recombination.  Binds and assemble on single-stranded DNA to form a nucleoprotein filament.  Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
What are the official names of this protein?
DNA repair and recombination protein RadA.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RecA-like protein family.
Protein: IDI2_RICCK
Sequence: MLKNQDLDIERKQEHIEINLTKNIESTLKSGFESIQFIHNALPEINYDNIDTTTTFLGKALQAPILISSMTGGTARARDINYRLAEAAQKAGIAMGLGSMRVLLAAADTIKTFAVRHIAPDILLLANIGAVQLNYGVTPKECQYLVDATKADALILHLNVLQELTQPEGNRNWANLLPKIREVINYLSVPVIVKEVGYGLSKQVAKSLIDVGVKTLDIAGSGGTSWSQVEAYRAKNSLQNRIASSFINWGIPTLDSLKMVREISKNVSIIASGGLKSGIDGAKAIRMGANIFGLAGQLLKAVDNSEYLVSEEIQLIIKQLKITMLCTGSRTLKDLTKAEIKL
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BACH_HALHS
Sequence: MTAVSTTATTVLQATQSDVLQEIQSNFLLNSSIWVNIALAGVVILLFVAMGRDLESPRAKLIWVATMLVPLVSISSYAGLASGLTVGFLQMPPGHALAGQEVLSPWGRYLTWTFSTPMILLALGLLADTDIASLFTAITMDIGMCVTGLAAALITSSHLLRWVFYGISCAFFVAVLYVLLVQWPADAEAAGTSEIFGTLKILTVVLWLGYPILWALGSEGVALLSVGVTSWGYSGLDILAKYVFAFLLLRWVAANEGTVSGSGMGIGSGGAAPADD
What is the function of this protein?
Light-driven anion pump.
What are the official names of this protein?
Halorhodopsin, HR.
What is the protein family that this protein belongs to?
Belongs to the archaeal/bacterial/fungal opsin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: METI_SALTY
Sequence: MSEAMMWLLVRGVWETLAMTFVSGFFGFVIGLPVGVLLYVTRPGQIMENARLYRSLSAVVNIFRSIPFIILLVWMIPFTRIIVGTSIGLQAAIVPLTVGAAPFIARMVENALLEIPAGLIEASRAMGATPLQIVRKILLPEALPGLVNAATITLITLVGYSAMGGAVGAGGLGQIGYQYGYIGYNATVMNTVLVLLVVLVYLIQLSGDRIVRAVTHK
What is the function of this protein?
Part of the binding-protein-dependent transport system for D-methionine and the toxic methionine analog alpha-methyl-methionine.  Probably responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
D-methionine transport system permease protein MetI.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NCAP_RVFV
Sequence: MDNYQELAIQFAAQAVDRNEIEQWVREFAYQGFDARRVIELLKQYGGADWEKDAKKMIVLALTRGNKPRRMMMKMSKEGKATVEALINKYKLKEGNPSRDELTLSRVAAALAGRTCQALVVLSEWLPVTGTTMDGLSPAYPRHMMHPSFAGMVDPSLPGDYLRAILDAHSLYLLQFSRVINPNLRGRTKEEVAATFTQPMNAAVNSNFISHEKRREFLKAFGLVDSNGKPSAAVMAAAQAYKTAA
What is the function of this protein?
Encapsidates the genomic RNA, protecting it from nucleases (Probable) (PubMed:20547879).  Displays high affinity for single-stranded nucleic acid (PubMed:23129612).  The encapsidated genomic RNA is termed the nucleocapsid (NC) or ribonucleoprotein (PubMed:20547879).  The ribonucleoprotein has a non-helical structure (PubMed:20547879).  Serves as template for viral transcription and replication (By similarity).  After replication, the nucleocapsid is recruited to the host Golgi apparatus by glycoprotein Gn for packaging into virus particles (By similarity).
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the phlebovirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Host nucleus. Host endoplasmic reticulum-Golgi intermediate compartment. Host Golgi apparatus.
Protein: QUEA_SHEHH
Sequence: MRVADFSFELPDELIARYPTAERTASRLLSLDGNSGELTDLQFTDILEQVNLGDLMVFNNTRVIPARMFGQKQSGGKLEILVERMLDDKRVLAHVRCSKSPKVDSIICLDGGYEMIMVARHDALFELELQSDKTILEVLEDVGHMPLPPYIDRPDEDADKERYQTVYNQNPGAVAAPTAGLHFDDAMLAALKDKGVNTAFVTLHVGAGTFQPVRVDNILDHKMHSEWAEVPQNVVDLIAETKTRGNRVIAVGTTSVRSLESAAKASPEQLEAFSGDTDIFIYPGYQFQVVDAMVTNFHLPESTLIMLLSAFAGFDEVKNAYQHAIAQKYRFFSYGDAMFVTKKAN
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASPD_THESQ
Sequence: MTVLIIGMGNIGKKLVELGNFEKIYAYDRISKDIPGVVRLGEFQVPSDVSTVVECASPEAVKEYSLQILKSPVNYIIISTSAFADEVFRERFFSELKNSPARVFFPSGAIGGLDVLSSIKDFVETVRIETIKPPKSLGLDLKGKTVVFEGSVEEASKLFPRNINVASTIGLIVGFEKVKVTIVADPAMDHNIHIVRISSAIGNYEFKIENIPSPENPKTSMLTVYSILRALRNLESKIVFG
What is the function of this protein?
Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
What are the official names of this protein?
L-aspartate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the L-aspartate dehydrogenase family.
Protein: ASB13_HUMAN
Sequence: MEPRAADGCFLGDVGFWVERTPVHEAAQRGESLQLQQLIESGACVNQVTVDSITPLHAASLQGQARCVQLLLAAGAQVDARNIDGSTPLCDACASGSIECVKLLLSYGAKVNPPLYTASPLHEACMSGSSECVRLLIDVGANLEAHDCHFGTPLHVACAREHLDCVKVLLNAGANVNAAKLHETALHHAAKVKNVDLIEMLIEFGGNIYARDNRGKKPSDYTWSSSAPAKCFEYYEKTPLTLSQLCRVNLRKATGVRGLEKIAKLNIPPRLIDYLSYN
What is the function of this protein?
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
Ankyrin repeat and SOCS box protein 13, ASB-13.
What is the protein family that this protein belongs to?
Belongs to the ankyrin SOCS box (ASB) family.
Protein: GLYA_PELPB
Sequence: MDTDILQKQDSELFEAIAKETGRQTETLELIASENFTSRAVMQACGSVMTNKYAEGYPGKRYYGGCEFVDIAENLARDRAKKLFGCDYVNVQPHSGSSANMAVLFSVLKPGDRIMGLDLSHGGHLTHGSSVNFSGQMYEAHSYGVDRETGCIDMNKVEELALQVRPKLIICGASAYSQGFDVKAFRVIADKVGAFLMADIAHPAGLIAAGLLGNPLPHCHFVTTTTHKTLRGPRGGMIMMGSDFENPMGITIKTKTGSRLKMMSEVMDAEVMPGIQGGPLMHIIAGKAVAFGEALQPAFRDYAAQVIKNAAAMAEKFTELGYKIVSGGTKNHLMLLDLRSKNVTGKVAENLLHSAGITVNKNMVPFDDKSPFVTSGIRVGTPAMTTRGMNEADSVLIAELIDRVITSAEKPDVADLCRSVREEIKALCLRNPIDGYTV
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPS_DESVM
Sequence: MIVGLGIDIAELSRIARAWERHGRRFAARVLHPAELACLPAAPVAFLAARFAAKEAAVKALGTGFSQGIGPRDIEVRPLPTGQPQLVLHGKAAARCAALGATATHVSLTHGRDTAAAVVVLER
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.