PharMolix/UniProtQA huggingface dataset:
Protein: SPDEF_HUMAN
Sequence: MGSASPGLSSVSPSHLLLPPDTVSRTGLEKAAAGAVGLERRDWSPSPPATPEQGLSAFYLSYFDMLYPEDSSWAAKAPGASSREEPPEEPEQCPVIDSQAPAGSLDLVPGGLTLEEHSLEQVQSMVVGEVLKDIETACKLLNITADPMDWSPSNVQKWLLWTEHQYRLPPMGKAFQELAGKELCAMSEEQFRQRSPLGGDVLHAHLDIWKSAAWMKERTSPGAIHYCASTSEESWTDSEVDSSCSGQPIHLWQFLKELLLKPHSYGRFIRWLNKEKGIFKIEDSAQVARLWGIRKNRPAMNYDKLSRSIRQYYKKGIIRKPDISQRLVYQFVHPI
What is the function of this protein?
May function as an androgen-independent transactivator of the prostate-specific antigen (PSA) promoter.  Binds to 5'-GGAT-3' DNA sequences.  May play a role in the regulation of the prostate gland and/or prostate cancer development.  Acts as a transcriptional activator for SERPINB5 promoter.
What are the official names of this protein?
SAM pointed domain-containing Ets transcription factor, Prostate epithelium-specific Ets transcription factor, Prostate-specific Ets, Prostate-derived Ets factor.
What is the protein family that this protein belongs to?
Belongs to the ETS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL2_HALMA
Sequence: MGRRIQGQRRGRGTSTFRAPSHRYKADLEHRKVEDGDVIAGTVVDIEHDPARSAPVAAVEFEDGDRRLILAPEGVGVGDELQVGVSAEIAPGNTLPLAEIPEGVPVCNVESSPGDGGKFARASGVNAQLLTHDRNVAVVKLPSGEMKRLDPQCRATIGVVAGGGRTDKPFVKAGNKHHKMKARGTKWPNVRGVAMNAVDHPFGGGGRQHPGKPKSISRNAPPGRKVGDIASKRTGRGGNE
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome (By similarity).
What are the official names of this protein?
50S ribosomal protein L2, Hl4, Hmal2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: CTAA_BARQU
Sequence: MAEKILNNDVLTSLQKKNRKQIQVWLYSILLLCLAIVLVGGATRLTGSGLSITDWRPIHGVIPPIGAEQWQEEFLKYQQIAQYKLLNRDMTLNAFKVIFWWEWAHRILGRLVGLLALLGLIWFWATKRIEKNILLKLTIVPILIAFQGAIGWWMVASGIGQSNLTSVSQYRLAFHLITACFIITFVTYLSRGFTEYSEKPANQRVQRFAGWLVVLILIEIYFGALVAGLHAGKVYNTWPLMDGQFIPDGLMQHNPVWLNLFENPLTIQFIHRFFAYFLFFVTIIHAFYVQKNIPHSTHSRRAFFICVMIVVQAFLGIITLLREVPIGLGLIHQSVALAILCFSVVHWRATKEAYRAVE
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EMRE_XENTR
Sequence: MAARVGVLSVAGFRAAARAGGLLRASKQSSAVSHVPCRTAIATSAGTVLPKPEKVSFGLLRVFTVVIPFLYIGTLISKNFAALLEEHDIFVPEDDDDDD
What is the function of this protein?
Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria.  Plays a central role in regulating the uniplex complex response to intracellular calcium signaling.
What are the official names of this protein?
Essential MCU regulator, mitochondrial, Single-pass membrane protein with aspartate-rich tail 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the SMDT1/EMRE family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: RS19_RUTMC
Sequence: MARSLRKGPFIDEHLIKKVLVAQEKNDRKPIKTWSRRSVVVPEMIGLTIAVHNGRVHVPVSINENMIGHKLGEFAITRTFKGHSGDRKV
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: E2ALA_AMOLO
Sequence: MFTLKKSMLLLFFLGTISLSLCEEERNADEDDGEKEVKRGIFALIKTAAKFVGKNLLKQAGKAGLEHLACKANNQC
What is the function of this protein?
Antimicrobial peptide with activity against Gram-positive and Gram-negative bacteria and against fungi (PubMed:19843479).  Has been tested against S. aureus (MIC=2. 5 ug/mL), B. pumilus (MIC=2. 5 ug/mL), B. cereus (MIC=7. 5 ug/mL), E. coli (MIC=12. 5 ug/mL), B. dysenteriae (MIC=7. 5 ug/mL), A. cacoaceticus (MIC=25. 0 ug/mL), P. aeruginosa (MIC=50. 0 ug/mL) and C. albicans (MIC=2. 5 ug/mL) (PubMed:19843479).  Also shows a weak hemolytic activity (PubMed:19843479).
What are the official names of this protein?
Esculentin-2-ALa, Amolopin-9a.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Esculentin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NDHJ_ARATH
Sequence: MQGTLSVWLAKRGLVHRSLGFDYQGIETLQIKPEDWHSIAVILYVYGYNYLRSQCAYDVAPGGLLASVYHLTRIEYGVNQAEEVCIKVFTHRSNPRIPSVFWVWKSTDFQERESYDMLGITYDSHPRLKRILMPESWIGWPLRKDYIAPNFYEIQDAY
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit J, chloroplastic, NAD(P)H dehydrogenase subunit J, NADH-plastoquinone oxidoreductase subunit J.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: MTNB_PSE14
Sequence: MSREQLSVEIIEAGRFLYGRGWSPATSSNYSARLSATEALLTVSGKHKGQLGPDDVLATDMAGNSLEPGKKPSAETLLHTQLYSSRPQVGAVLHTHSVNATVLSRLTAADHLVFEDYELQKAFHGVVTHQSQVVVPIFDNDQDIARLAAKVQPWLDAHPECAGYLIRGHGLYTWGAKMSDALRQIEAFEFLFECELKMRAVLNR
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
What are the official names of this protein?
Methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
Protein: MURC_PSEAE
Sequence: MVKEPNGVTRTMRRIRRIHFVGIGGAGMCGIAEVLLNLGYEVSGSDLKASAVTERLEKFGAQIFIGHQAENADGADVLVVSSAINRANPEVASALERRIPVVPRAEMLAELMRYRHGIAVAGTHGKTTTTSLIASVFAAGGLDPTFVIGGRLNAAGTNAQLGASRYLVAEADESDASFLHLQPMVAVVTNIDADHMATYGGDFNKLKKTFVEFLHNLPFYGLAVMCVDDPVVREILPQIARPTVTYGLSEDADVRAINIRQEGMRTWFTVLRPEREPLDVSVNMPGLHNVLNSLATIVIATDEGISDEAIVQGLSGFQGVGRRFQVYGELQVEGGSVMLVDDYGHHPREVAAVIKAIRGGWPERRLVMVYQPHRYTRTRDLYEDFVQVLGEANVLLLMEVYPAGEEPIPGADSRQLCHSIRQRGQLDPIYFERDADLAPLVKPLLRAGDILLCQGAGDVGGLAPQLIKNPLFAGKGGKGA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA2_HUMAN
Sequence: MAFAETYPAASSLPNGDCGRPRARPGGNRVTVVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINPNVTAFIGNGVVIHLPGLFEEAEKNVQKGKGLEGWEKRLIISDRAHIVFDFHQAADGIQEQQRQEQAGKNLGTTKKGIGPVYSSKAARSGLRMCDLVSDFDGFSERFKVLANQYKSIYPTLEIDIEGELQKLKGYMEKIKPMVRDGVYFLYEALHGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQDNEIGELLQTRGREFGVTTGRKRRCGWLDLVLLKYAHMINGFTALALTKLDILDMFTEIKVGVAYKLDGEIIPHIPANQEVLNKVEVQYKTLPGWNTDISNARAFKELPVNAQNYVRFIEDELQIPVKWIGVGKSRESMIQLF
What is the function of this protein?
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase isozyme 2, AMPSase 2, AdSS 2, Adenylosuccinate synthetase, acidic isozyme, Adenylosuccinate synthetase, liver isozyme, L-type adenylosuccinate synthetase, IMP--aspartate ligase 2.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Note=Partially associated with particulate fractions.
Protein: TRMB_YEAST
Sequence: MKAKPLSQDPGSKRYAYRINKEENRKELKHVKINESSLVQEGQKIDLPKKRYYRQRAHSNPFSDHQLEYPVSPQDMDWSKLYPYYKNAENGQMTKKVTIADIGCGFGGLMIDLSPAFPEDLILGMEIRVQVTNYVEDRIIALRNNTASKHGFQNINVLRGNAMKFLPNFFEKGQLSKMFFCFPDPHFKQRKHKARIITNTLLSEYAYVLKEGGVVYTITDVKDLHEWMVKHLEEHPLFERLSKEWEENDECVKIMRNATEEGKKVERKKGDKFVACFTRLPTPAIL
What is the function of this protein?
Methyltransferase that catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA, a modification required to maintain stability of tRNAs; its absence resulting in tRNA decay.  Both the D-stem and T-stem structures of tRNAs are required for efficient methyltransferase activity.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, Transfer RNA methyltransferase 8, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: REEP5_HUMAN
Sequence: MSAAMRERFDRFLHEKNCMTDLLAKLEAKTGVNRSFIALGVIGLVALYLVFGYGASLLCNLIGFGYPAYISIKAIESPNKEDDTQWLTYWVVYGVFSIAEFFSDIFLSWFPFYYMLKCGFLLWCMAPSPSNGAELLYKRIIRPFFLKHESQMDSVVKDLKDKAKETADAITKEAKKATVNLLGEEKKST
What is the function of this protein?
Plays an essential role in heart function and development by regulating the organization and function of the sarcoplasmic reticulum in cardiomyocytes.
What are the official names of this protein?
Receptor expression-enhancing protein 5, Polyposis locus protein 1, Protein TB2.
What is the protein family that this protein belongs to?
Belongs to the DP1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Sarcoplasmic reticulum membrane; Multi-pass membrane protein. Note=Localizes to endoplasmic reticulum tubular network (PubMed:23969831). In cardiomyocytes, localizes to the junctional sarcoplasmic reticulum membrane which is closely tethered to the cell membrane and contractile machinery (By similarity).
Protein: RL1_GEOSW
Sequence: MPKRGKKYLEAAKLVDRFKAYPIAEAIELVKKTNIAKFDATVEVAFRLGVDPKKADQQIRGAVVLPHGTGKVQRVLVFAKGEKAKEAEAAGADYVGDTEYINKIQQGWFDFDVVVATPDMMGEVGKLGRILGPKGLMPNPKTGTVTFDVAKAVQEIKAGKVEYRVDKAGNIHVPIGKVSFDNEKLAENFTTIYEAILKAKPAAAKGTYVKNVTITSTMGPGIKVDPSTVAVAQ
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: GALB_PSEPK
Sequence: MTSCAHPHCRSQRNMNTPQKSALVVSAHSADFVWRAGGAIALHAEQGYAMHVVCLSFGERGESAKLWRKGEMTEAKVKDARREEAMAAAEILGASVEFFDIGDYPMRADKDTLFRLADVYRRVQPEFVLSHSLKDPYNYDHPLAMHLAQEARIIAQAEGYKPGEKIVGAPPVYAFEPHQPEQCEWRPDTFLDITSVWDKKYAAIQCMAGQEHLWEYYTRVALQRGVQAKRNVGITSARNIVYAEGLQSVFPRVTENLA
What is the function of this protein?
Catalyzes the conversion of oxalomesaconic acid enol (OMAenol) to 4-carboxy-4-hydroxy-2-oxoadipic acid (CHA).  Mediates the third step of gallate degradation pathway.
What are the official names of this protein?
4-oxalmesaconate hydratase, OMA hydratase, Gallate degradation protein B.
What is the protein family that this protein belongs to?
Belongs to the MshB deacetylase family.
Protein: PHB_RALPI
Sequence: MVRRLWRRIAGWLAACVAILCAFPLHAATAGPGAWSSQQTWAADSVNGGNLTGYFYWPASQPTTPNGKRALVLVLHGCVQTASGDVIDNANGAGFNWKSVADQYGAVILAPNATGNVYSNHCWDYANASPSRTAGHVGVLLDLVNRFVTNSQYAIDPNQVYVAGLSSGGGMTMVLGCIAPDIFAGIGINAGPPPGTTTAQIGYVPSGFTATTAANKCNAWAGSNAGKFSTQIAGAVWGTSDYTVAQAYGPMDAAAMRLVYGGNFTQGSQVSISGGGTNTPYTDSNGKVRTHEISVSGMAHAWPAGTGGDNTNYVDATHINYPVFVMDYWVKNNLRAGSGTGQAGSAPTGLAVTATTSTSVSLSWNAVANASSYGVYRNGSKVGSATATAYTDSGLIAGTTYSYTVTAVDPTAGESQPSAAVSATTKSAFTCTATTASNYAHVQAGRAHDSGGIAYANGSNQSMGLDNLFYTSTLAQTAAGYYIVGNCP
What is the function of this protein?
This protein degrades water-insoluble and water-soluble PHB to monomeric D(-)-3-hydroxybutyrate.
What are the official names of this protein?
Poly(3-hydroxybutyrate) depolymerase, PHB depolymerase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: NSF1C_DICDI
Sequence: MSDHSEAIATFQSITGASKEESTFYLESHDWDLEKAAQTFTTLQEEENQRNDQPQIEEDYEDEEEEDDHRDPMPASRPVYSKPVAKTVSKKAPAGGRVGGIRTLSDFNNDDHDDHDHSDGDDDEDDRSQQYFTGGEKSGLVVESAPKKGKNGGSGDIVNDVFDSAKRHGAVASNEKKVEKPDSFDSVGYQLGATDQGNRNVSKPKEKDPNSQVVEVKVTFWNQGFTIDDGPLRKYDNPENKELLDDIQRGIVPRELQKKATTPNGLSVTLINNHNQDYVEPAKPKYVAFSGGGQTLGSSSTSTNNNNNNNNNNNNRATTTSTTTTSTPNVSSINVDQSQPTTTVQIRLANGSRLSTTFNHSHTLQDVINYINSSSGSNQSFDLLTGFPQKPVTNPTSTTLKDAGLLNALLIQKLK
What is the function of this protein?
Reduces the ATPase activity of VCP.  Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis.  May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER).  Regulates the centrosomal levels of kinase aurK/Aurora during mitotic progression by promoting aurK removal from centrosomes in prophase.  Also, regulates spindle orientation during mitosis.
What are the official names of this protein?
NSFL1 cofactor p47 homolog.
What is the protein family that this protein belongs to?
Belongs to the NSFL1C family.
What are the subcellular locations of this protein?
Nucleus. Golgi apparatus, Golgi stack. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: SYGB_HISS2
Sequence: MTAQNFLAEIGTEELPPKALKKLATAFAENVEQELNQAGLAFEKVEWFAAPRRLAVKVLGLAEAQPSKQVEKRGPAVSAAFDAEGKPTKAAEGWARGCGITVEQAERLATDKGEWLVHRAVIEGQPTKNLLVGIIDKALAGLPIPKTMRWGDKTEQFVRPVHTVTLLFGADLIEGEILGVASGRTVRGHRFLGEREFSLDHADQYPQLLKERGSVVADFNERKALILATSQEKATALGGVADIEEELLEEVTSLVEYPNVLTAKFEERFLAVPAEALVYTMKGDQKYFPIYDKDGKLLPHFIFVSNINPDDPSKIIEGNEKVVRPRLTDAEFFFKTDLKQKLEDRLPRLETVLFQQQLGTLRDKTARIEALAGEIAAQIGADQTKAKRAGLLSKCDLMTNMVFEFTDTQGVMGMHYARHDGEDEDVAVALNEQYMPRFAGDTLPNSLVACSVALADKIDTLTGIFGIGQSPKGSADPFALRRAALGCLRIIVEKNLPLDLVDIVAKATALFGDKLTNKNVVDEVVDFMLGRFRAWYESEGIAVDVIQSVLARRPTKPADFDARVRAVSHFRTLDSAEALAAANKRVSNILAKADIAIGEIDLGVCVESAEKTLAEAVIALKGEVQPLIAQGDYTAVLDKLANLRQPIDAFFDGVMVNVEEQTLRQNRLAILSTLQNLFLQVADISVLQ
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAY_ANADE
Sequence: MLYHLLYPLAYKLSLLNVLRYPSFRIVAAGLTAMVLGLLLGPIFIERMRVLQYGSTNVREDTPDTHKKKAGTPSMGGALILASVAIATLLFADLANRFVWAALLVTLGYGAIGFTDDWLKISKKNSKGLAGKKKLVLQVLVVVVVYYACLTDWRFHVEHRFPWVFVGSYVDLHVTLPFVPSRLFNPDLGFLYLPFMVFVVIATSNAVNLTDGLDGLAIGPTVVSAMTFLALSYVAGATIAGFSLAEYLRVPYIPGAEELGVFCSAIFGAGVAFLWYNTYPASVFMGDVGSLALGGGLGMMAVLTKNEFASAILHGVFLTETVSVILQVWSFKTTGKRIFRMAPIHHHYELKGWAEPKIIVRFWIISVMLALVALLSIKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EBNA5_EBVB9
Sequence: MGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQEPRRVRRRVLVQQEEEVVSGSPSGPRGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQEPRRVRRRVLVQQEEEVVSGSPSGPRGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQEPRRVRRRVLVQQEEEVVSGSPSGPRGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQEPRRVRRRVLVQQEEEVVSGSPSGPRGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQEPRRVRRRVLVQQEEEVVSGSPSGPRGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQEPRRVRRRVLVQQEEEVVSGSPSGPRGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQEPRRVRRRVLVQQEEEVVSGSPSGPLRPRPRPPARSLREWLLRIRDHFEPPTVTTQRQSVYIEEEEDED
What is the function of this protein?
Plays an important role in the establishment of B-cell immortalization by acting as an EBNA2 coactivator.  This transcriptional activation preferentially enhances the expression of the major viral protein LMP1.  The interaction between EBNA-LP and host SP100 correlates with coactivation of EBNA2 and the relocalization of SP100 from PML nuclear bodies into nucleoplasm.
What are the official names of this protein?
Epstein-Barr nuclear antigen leader protein, EBNA-LP, EBV nuclear antigen leader protein, Epstein-Barr nuclear antigen 5, EBNA-5, EBV nuclear antigen 5.
What is the protein family that this protein belongs to?
Belongs to the lymphocryptovirus EBNA-LP family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: GET3_CHAGB
Sequence: MSATLINVDDGDAMEPTLQSILDQRSLRWIFVGGKGGVGKTTTSCSLAIQLAKVRRSVLLISTDPAHNLSDAFSQKFGKEARLIDGFENLSAMEIDPNGSIQDLLAGQGEGDAGADMGGMGGMMQDLAFAIPGIDEAMSFAEVLKQVKSLSYETIIFDTAPTGHTLRFLQFPSVLEKALAKVSQLSNQYGPLLNGFLGSNGTLPNGQNLNEMMEKLETLRATISEVNTQFKDERLTTFVCVCIPEFLSLYETERMIQELASYGIDTHSIVVNQLLFPKPGSDCEQCTARRRMQKKYLEQIEELYDEFNVVKMPLLVEEVRGKERLERFSEMLVTPFVPPS
What is the function of this protein?
ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion.  This process is regulated by ATP binding and hydrolysis.  ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins.  ATP hydrolysis is required for insertion.  Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
What are the official names of this protein?
ATPase GET3, Arsenical pump-driving ATPase, Arsenite-stimulated ATPase, Golgi to ER traffic protein 3, Guided entry of tail-anchored proteins 3.
What is the protein family that this protein belongs to?
Belongs to the arsA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum.
Protein: SYL_BRUSI
Sequence: MAAERYNPRVAEAHWQKVWEENRTFETDNSDSREKYYVLEMFPYPSGRIHMGHVRNYAMGDVVARYKRAKGFNVLHPMGWDAFGMPAENAAMQNKVHPKEWTYQNIATMKRQLKSMGLSLDWSREFATCDVEYYHRQQMLFIDLYEKGLVTRKTSKVNWDPVDNTVLANEQVVDGRGWRSGALVEQRELTQWFFKITDFSEELLAGLDTLDQWPEKVRLMQRNWIGKSEGLQVRFALAAGTAPAGFSEVEVYTTRPDTLFGAAFVAISADHPLAKKLSEGNAALSSFIEECHQQGTSLAALETAEKKGFDTGIKVKHPFDDNWELPVYVANFVLMEYGTGAVFGCPAHDQRDLDFANKYKLKVTPVVLPKGEDAASFSIGETAYTDDGVMINSRFLDGMTPEAAFNEVASRLEKTDLVGRPQAVRKVQFRLRDWGISRQRYWGCPIPMIHCESCGVNPVPRADLPVKLPDDVEFDRPGNPLDRHATWRHVKCPKCGGDARRETDTMDTFVDSSWYYTRFTAPWENEPTDRKAADHWLPVDQYIGGIEHAILHLLYSRFFTRAMKVAGHVGVDEPFKGLFTQGMVVHETYKANGQWVSPADIRIEEIDGKRVATMLDSGAPVEIGSIEKMSKSKKNVVDPDDIIASYGADTARWFVLSDSPPERDVIWTEAGAEGAHRFVQRIWRLVAEAAPALKDVAPKAGTQGEALGVSKAAHKAVKAVGDDIEKLAFNRGVARLYELVNTLSGALQQAADGKADAEMKGALREATEMLVLMTAPMMPHLAEQCLAELGGKVAGKETLVARAPWPVFDPALVVENEIVLPVQINGKKRGDLTIARDADQASIQQAVLELDFVKAALNGGSPKKIIVVPQRIVNVVA
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYV_ACIAD
Sequence: MIFIMTDAHAQSAQNIATTYDPTDIERKWYQIWEEKGYFKPSGQGDSFCIMIPPPNVTGSLHMGHGFNNAIMDALTRYNRMMGKNTLWQPGTDHAGIATQMVVERQLAAQNISRHDLGREQFIDKVWEWKEQSGGTITKQIRRLGSSVDWSRERFTMDDGLSNAVKEVFVKLHEDGLIYRGKRLVNWDPKLQTALSDLEVESVEEKGSLWHFKYFFEDKSLKTQDGHDFLVVATTRPETLLGDTAVAVHPEDERYAHLIGKNIVLPITGRLVPIVADEYVEKDFGTGCVKITPAHDFNDYDLGKRHDLPIINIFNKNAEVLAEFEYIAKAGEQISDAIAAPADYVGLERFAARKKLVAQAEAEGWLDQIQPYDLKAPRGDRSGVIVEPLLTDQWYVKIAPLAQPAIEAVQDGRIKFVPEQYTNMYMAWMNNIQDWCISRQLWWGHRIPAWYDAEGNVYVGRNEEEVRAKNNLAADLALQQDEDVLDTWFSSGLWTFSTLGWTGDAKKDAENYFLNTFHPTDVLVTGFDIIFFWVARMIMMTMHFMKNEDGTPQVPFKTVYVHGLVRDGEGQKMSKSKGNVLDPLDLIDGIDLESLVQKRTFGLMNPKQAEKIEKATRKEFPEGINSYGTDAVRFTFCALANTGRDIKFDLKRVEGYRNFCNKIWNATRFVLMNVEGQTVAQEARPELWELPEQWIMSRLQKAEQAVHQAFATYRLDLAAQTIYDFIWNEYCDWYVELTKPVLNDAEVSEERKAEVRRVLLAVMEASLRLAHPLMPYLTEEIWQTLAPMIGKGGDTIMTAKYPVPEAAKMNEQAEADMQWLQGLIGAVRNIRGEMGLGNARLLPVLLQNISDSERTQIERIQPLFKALAKVESITFLAQGEEPPLSSSSVVGHASVFVPMKGLIDPKAELGRLQKDLDKVQKQHDQIASKLANEGFVAKAPAAVVEGEKVKLAEFADQLVKIKQSMEQIAAL
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOT9_PONAB
Sequence: MELKKSPDGGWGWVIVFVSFFTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASGVGLLASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYTATVTITCLYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILACGSLMRPLQSSDCPLPKKIAPEDLPDKYSIYNEKGKNLEENINILEKSYSSEEKCRTTLANGDWKQDSLLHKNPTVTHTKEPETYKKKVAEQTYFCKQLAKRKWQLYKNYCGETVALFKNKVFSALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMPLISIIGIMTAVGKLLLGILADFKWINTLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTGNWSIFPYVTTKTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYEIAFYFSGFCVLLGGFILLLAALPSWDTCNKQLPKPAPTTFLYKVASNV
What is the function of this protein?
Extracellular pH-and Na(+)-sensitive low-affinity creatine transporter.  Functions also as a pH-independent carnitine efflux transporter.
What are the official names of this protein?
Monocarboxylate transporter 9, MCT 9, Solute carrier family 16 member 9.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YHI1_AZOBR
Sequence: MTDVTVERIDTLKTGDLHDLCDAADDAVKAGGGFGWVAPPAREIMERYWKGVLVVPERILFVGRLDGVIAGSAQLVKPARNNEAQAHAATLTTSFVAPWARCHGLARRLTVAVEEEARASGFRVLNLDVRETQRRQPSRCTRIWASAVGARIPSMRWWTAKGWPDISM
What are the official names of this protein?
Uncharacterized N-acetyltransferase in hisH-hisA intergenic region, ORF1.
Protein: MSHB_NOCSJ
Sequence: MTFDQRLLLVHAHPDDESIGQGATMAKYAAEGRGVTLVTCTGGEMGEILVPELTHLAADQEDRLGEHRRGELDAAMAELGVTDHRYLGGFGTYRDSGMKWHEDGHAVPADDIHQNAFWHADLTEAADHLVAVIREVRPQVLVTYDQFGGYGHPDHIQAHRVATYAAALAAVPSYRKDLGAAWDIAKIYWGAMSESRMRAALRALREAGDTTAFEGMDPDGPLPPFVTADEDLSAVVDAQEHVEAKLAAMRAHATQITTDGPFFALSNNVGNVAWGLEFFRLAKGERGELNQDGLETDLFAGL
What is the function of this protein?
Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.
What are the official names of this protein?
1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase, GlcNAc-Ins deacetylase, N-acetyl-1-D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase.
What is the protein family that this protein belongs to?
Belongs to the MshB deacetylase family.