PharMolix/UniProtQA huggingface dataset:
Protein: YDIM_ECOLI
Sequence: MKNPYFPTALGLYFNYLVHGMGVLLMSLNMASLETLWQTNAAGVSIVISSLGIGRLSVLLFAGLLSDRFGRRPFIMLGMCCYMAFFFGILQTNNIIIAYVFGFLAGMANSFLDAGTYPSLMEAFPRSPGTANILIKAFVSSGQFLLPLIISLLVWAELWFGWSFMIAAGIMFINALFLYRCTFPPHPGRRLPVIKKTTSSTEHRCSIIDLASYTLYGYISMATFYLVSQWLAQYGQFVAGMSYTMSIKLLSIYTVGSLLCVFITAPLIRNTVRPTTLLMLYTFISFIALFTVCLHPTFYVVIIFAFVIGFTSAGGVVQIGLTLMAERFPYAKGKATGIYYSAGSIATFTIPLITAHLSQRSIADIMWFDTAIAAIGFLLALFIGLRSRKKTRHHSLKENVAPGG
What are the official names of this protein?
Inner membrane transport protein YdiM.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NTPP_HELPY
Sequence: MELILGSQSSTRANLLKEHGIKFEQKALYFDEESLKTTDPREFVYLACKGKLEKAKELLANNCAIVVADSVVSVGNRMQRKAKNKQEALEFLKRQNGHEIEVLTCSALISPVLEWLDLSVFRARLKAFDPSEIEKYLESGLWQESAGCVRLEDFHKPYIKSSSENLSVGLGLNVEGLLGALKLGAKLSSL
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTOL1_MOUSE
Sequence: MWIFSSLCAVLTILAMDDVATEAKTTPYTKFTKKSEGKEMLKGLKPSSGFFLDGEETVHTETAAMAEPTTGSPALAMAESTAGPSASATTRLLPFESFSLDTTGFVLNCCHCCSFVTGQKGEPGKMGKQGPKGETGDTGSPGHPGTTGPQGPKGQKGEKGLKGDRGDQGAGGIPGYPGKPGEQGALGPKGDKGTIGPAGTKGQKGSKGELCGNGTKGEKGDPGASGAHGFIGEPGAKGEKGGVGEKGYRGDLGERGEKGQKGEKGMEGEKGSRGDVGSEGKRGSDGLPGLRGDSGPKGEKGEIGSPGFTGPAGPKGELGSKGVRGPTGKKGSRGVKGSKGEATQVPQSAFSALLSKPFPPPNVPIKFDKILSNDQGDYSPVTGKFNCSVPGTYIFSYHVTVRGRPARISLVARNRKQFKSRETLYGQQVDQASLLLILKLSAGDQVWLEVSKDWNGLYVGPEDDSIFSGFLLYPEETFSKSP
What is the function of this protein?
Collagen-like protein specifically expressed in the inner ear, which provides an organic scaffold for otoconia, a calcium carbonate structure in the saccule and utricle of the ear (PubMed:21655225, PubMed:24748133, PubMed:29076638).  Acts as a scaffold for biomineralization: sequesters calcium and forms interconnecting fibrils between otoconia that are incorporated into the calcium crystal structure (PubMed:21655225, PubMed:24748133, PubMed:29076638).  Together with OC90, modulates calcite crystal morphology and growth kinetics (PubMed:24748133).
What are the official names of this protein?
Otolin-1.
What is the protein family that this protein belongs to?
Belongs to the OTOL1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Note=Localized in both the surrounding otoconial matrix and otoconia.
Protein: TX51A_ETHRU
Sequence: MLSLGVSIFLLVFLIPENSGLECYQCTWMKNSQSPDNCYKNLPNATACAKDMIYCVTDERYEDDEFISIRRFCSSMPMDGRCTEVGKAKDCKYSCEVDACNFSTSIEPSKVFVFSILAMGLVLHT
What are the official names of this protein?
U-scoloptoxin(05)-Er1a, U-SLPTX(05)-Er1a.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-05 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS21_GEOMG
Sequence: MPGVKVKEAEPFELALKKFKKQCEKAGILSEVRKREHYEKPSIKKKKKAIAARKRAMKKQRKMMD
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: ATPA_PROM9
Sequence: MVSIRPDEISSILKQQITDYDQSVSVSNVGTVLQIGDGIARIYGLDQVMAGELLEFEDGTEGIALNLEDDNVGAVLMGEALGVQEGSNVKSTGKIASVPVGEAMQGRVVNPLGQPIDGKGEIPTSDTRLIEEMAPGIIKRRSVHEPMQTGITSIDAMIPVGRGQRELIIGDRQTGKSAIAIDTIINQKGQDVVCVYVAIGQKSASVANVVEVLREKGALDYTIVVSAGASEAAALQYLAPYTGAAIAEHFMYQGKATLVIYDDLTKQAQAYRQMSLLLRRPPGREAYPGDVFYCHSRLLERAAKLSDDMGGGSMTALPIIETQAGDVSAYIPTNVISITDGQIFLSADLFNSGLRPAINVGISVSRVGGAAQTKAIKKIAGTLKLELAQFDELAAFSQFASDLDEATQQQLERGKRLRELLKQAQFSPLNLAEQVAVVYAGVKGLIDEVPVEDVTKFAAELREYLKLNKAEFIEEILKEKKLNDGLEATLKEVIKEVKSSMLATV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: NU5C_ACOAM
Sequence: MEHTYQYAWIIPFLPFPVTISIGLGLLLVPTATKNLRRIWAFFSVLLLSIAMVFSADLAIQQINGSFIYQYSWSWTINNTFSLEFGYLIDPLTSIMLILITTVGIMVLIYSDNYMSHDQGYLRFFAYMSFFNTSMLGLVTSSNLIQIYIFWELVGMCSYLLIGFWFTRPTAANACQKAFVTNRVGDFGLLLGILGLYWITGSFEFRDLFEILKNLIHNNEVNSLFAALCASLLFVGAVAKSAQFPLHVWLPDAMEGPTPISALIHAATMVAAGIFLVARLLPLFTVIPYIMNFISLIGIITVLLGATLALAQRDIKRSLAYSTMSQLGYIMLAPGIGSYRAALFHLITHAYSKALLFLGSGSIIHSMEPIVGYSPEKSQNMILMGGLRRYVPITKTTFFLGTLSLCGMPPLACFWSKDEILNDTWLYSPIFAIIAWSTAGLTAFYMFRVYLLTFDGHLQVHFQNFSSTKNSSFYSISIWGKEVPKPLNVNLFLSTMNTNEKMSFFSKNTYQIDRNGKNRIRYFSTQFGNKYTSMYPHESDNTMLFPMLVLVLFTLFIGFIGIPFDQGVIDLDILSKWLTPSINLLHSNSGDSFDWYEFVTNAIYSVTISFLGIFLAYIFYGSVYSSFQNLDLINSFVRIDSKRILSDRIINGIYNWSYNRGYIDVFYGKVLSNTIRGLAELIHFFDRRVIDGITNGVGVVSFFVGEGIKSVGGGRISSYIFLYAFSVSICLIIYYFFSF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 5, chloroplastic, NAD(P)H dehydrogenase subunit 5, NADH-plastoquinone oxidoreductase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: NOSR_PSEAE
Sequence: MRALRFSAGSWRCVFAWMLLLVGLAAQGAELSELERLRIAQVFPAVERIGDPEGDYGVRRLSKGEETLGYAFQTLSVTDIPAYSGKPINLQVILDPQAVIRDAYVLEHHEPILLIGIPEEKLHAFSARYDGVRADQRVVVGRSSDPQAVTVDAVSGATVTVMVVNEIVMRAAHTVAVALGLIEDRGNVRPKPAQVRQQPAATASWSELLGNGAIRRLQLSRGQIDDAFKGSEAEGIGEADAAHRDEPFIDLYSALLNPPAVGRSLLGDNQYRELMASLKPGEYAFVVLGDGEYSFKGSGYVRGGIFDRVQLRQFGDIISFRDLDYQRLSDVYAEGMPEFREMAIFVARASQRFDPGSPWTLELLVRRQTGPVAGVFTSFELACQTPEEYLERPQPTAEELAALEEAARPLWLRVWYQKSFQVGVLCTALVLLLAILFLQDRLVRRPRLMQRLRTGYLAFTLVYLGWYSLGQLSVVNVLTFVHALFEGFRWELFLSDPLLFILWTFTAASLLLWGRGVFCGWLCPFGALQELLNELARKLRVPQFQVPFAVHERLWAIKYIILLVLFGLSLESLALAEQAAEVEPFKTAITLGFDRQWWFVAYAVALLVVNLFTRKVYCRYLCPLGAALAIPAKARLFDWLKRRAECGRPCQLCARECEIQAIHPDGRIEANECHYCLDCQMTYHDQDKCPPLVNKRKKRAKSAPADNARIPAENL
What is the function of this protein?
Transcriptional activator of the nitrous-oxide reductase gene NosZ.
What are the official names of this protein?
Regulatory protein NosR.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: LEU3_GLOVI
Sequence: MGGRYKIAVLPGDGIGTEIVQVGVAMLEAAARRFDFAFDFEEAPIGGAAIDATGEPLPAATLELCKASDAVFLGAVGGPQWDTLPSDKRPEKALLGLRAGLGLFANLRPARILPQLVAASALKPEVVEGVDILVVRELTGGLYFGIPKGIFPEKKGGRRGVNTMSYSAFEIERIGRVAFEAARERRGKLCSVDKANVLEVSQLWREVLVGLAPEYPDVELTHMYVDNCAMQLVRRPRQFDTIVTENMFGDILSDEAAMLTGSIGMLPSASLGSGGPGLYEPVHGSAPDIAGQDKANPLAQVLSGAMLLRHSLRQPEAAQAVERAVQTVLEQGYRTGDIAAPGAQIVGCRAMGEQLLAAFERA
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPS_PEDPA
Sequence: MIYGIGIDITNIDRFKTLHNPATFIQKVLTPTEFDEFEAKKGQRAYEFLAGHFSVKESYSKAYGTGLGKKLNFQDIEINYDGVGKPKIVKHPFSGTVHVSISHSDHHVVTQVILEGDN
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_BACAN
Sequence: MNKEERAKRQSKIRNFSIIAHIDHGKSTLADRILEKTNALTQREMKAQLLDSMDLERERGITIKLNAIQLNYKAKDGEEYILHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNNLEILPVINKIDLPSADPERVRQEVEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDSEEPLQCMIFDSLYDPYRGVIAYIRVVNGTVKVGDKVRMMATGKEFEVTEVGVFTPKTTQRDELTVGDVGFLAASIKNVGDTRVGDTITHAKRPAAEPLAGYRKLNPMVFCGLYPIDSARYNDLRDALEKLELNDSALEFEPETSQALGFGFRCGFLGLLHMEILQERIEREFKIDLITTAPSVIYKVFLTNGEDMIVDNPSNMPDPQTIDRVEEPFVKAAIMVPNDYVGAVMEICQGKRGTFIDMQYLDETRVTLTYEIPLSEIVYDFFDQLKSNTKGYASFDYELIGYKPSKLVKMDILLNSEQVDALSFIVHRDSAYDRGKVIVEKLKELIPRQQFEVPIQATIGNKVVARSTIKAMRKNVLAKCYGGDISRKRKLLDKQKEGKKRMKSVGSVEVPQEAFMAVLKMDDN
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: AROK_METJA
Sequence: MEGKAYALASGTIINAIATGKGSAFGLDLKVYAKVKLIDDGKNKIEGKVLDNPNIKPNLIVRCVKNTLDYFGLNYSAYVETKTEIPIKSGLSSSSATSNAVVLATFDALGEKIDDELILNLGIKSSFDEKLTVTGAYDDATASYYGGITITDNIERKILKRDKMRDDLNVLILIPNLEKNVDVNRMKLIKDYVEIAFNEAINGNYFKALFLNGILYASALNFPTNIAIDALDAGAITAGLSGTGPSYIAMVEDENVEKVKEKLNRYGKVILTKPNNDGASIY
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR9_LEPBA
Sequence: MIQIKRALVSVSDKTGITEICSFLTKHGVEILSTGGTYDALSKAGIAVKKVDEFTGFPEILHGRVKTLHPKIHGGLLGDTTNPDHVKQMESNGIVPITLVIVNLYPFVKTVMKPDVTLEDAIENIDIGGPSMLRSAAKNHKNVVVLTDPKDYESFQNEFTTNNGKISRETAFGYAAKVFSETASYDSAISSYFNKRLGIKYPDKITFAFNKKQKLRYGENPHQDAAFYEPLFLKSQFEALQGKELSFNNMLDFDAAFHVASLLPKNAVSIVKHLNPCGIAFGETVLESFELARKTDPISAFGGIIGIHGRVEKESAEEITKNFVEGVIAESFSNEALEIFAKKPNIRLIPIAKFDEALDELDLRSLHHGLLIQNRDYDLITKDKLKIVSKKQPTEDDLEGLMFAWNCVKFIKSNAIVYTDQNSTLGIGAGQMSRVDSVELGAMKAQKVGLSVVGSYVGSDAFFPFRDGIDAIAKVGAKAIIQPGGSIRDEEVIQAADEHGLIMVFTGMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: DDL_BRASO
Sequence: MTSERIRVAILFGGRSAEHDVSRASAANIFRSLDAGRYALTLIGITHDGRWVLADAVNDATSAALIVPADGPQIVLLPAGRGRALAIDGSAAAPRELAFDVIFPVLHGPNGEDGTVQGALELADVAYVGGRVLGSAAAMDKDVAKRLLRDAGLPIVPFVTMTAASPVSYDDAARAVGSSELFVKPANLGSSVGISKTRDAAEFEAACQLALRFDRKILIERCIAPVREIECAVLEHADGQIKASELGEIVPANSHGFYSYEAKYTDANGAALHVPAQVEPAVAQRIRKMATEVFGALCCESLARVDFFVRGDEIYVNEVNTLPGFTNISMYPKMWEAAGLPQPALMDELVAHALARHARLRELASQR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REP_ABMVW
Sequence: MPPPKKFRVQAKNYFLTYPQCSLTKDEALSQLQNLETPVNKKFIKICRELHENGEPHLHVLIQFEGKYQCTNNRFFDLVSPTRSAHFHPNIQGAKSSSDVKSYIDKDGDTAEWGEFQIDGRSARGGQQTANDSYAKALNAGDVQSALNILKEEQPKDYVLQNHNIRSNLERIFAKAPEPWVPRFPLSSFTAVPEEMQEWADDYFGSGSAARPDRPLSLIVEGDSRTGKTMWARALGPHNYLSGHLDFNGRVYSNEVEYNVIDDVAPHYLKLKHWKELLGAQKDWQSNCKYGKPVQIKGGIPAIVLCNPGEGSSYKEYLDKEENTGLRNWTLKNAIFITLTAPLYQEGTQAGQEEGH
What is the function of this protein?
Essential for the replication of viral ssDNA.  The closed circular ssDNA genome is first converted to a superhelical dsDNA.  Rep binds a specific region at the genome origin of replication.  It introduces an endonucleolytic nick within the conserved sequence 5'-TAATATTAC-3' in the intergenic region of the genome present in all geminiviruses, thereby initiating the rolling circle replication (RCR).  Following cleavage, binds covalently to the 5'-phosphate of DNA as a tyrosyl ester.  The cleavage gives rise to a free 3'-OH that serves as a primer for the cellular DNA polymerase.  The polymerase synthesizes the (+) strand DNA by rolling circle mechanism.  After one round of replication, a Rep-catalyzed nucleotidyl transfer reaction releases a circular single-stranded virus genome, thereby terminating the replication.  Displays origin-specific DNA cleavage, nucleotidyl transferase, ATPase and helicase activities (By similarity).
What are the official names of this protein?
Replication-associated protein, Rep, Protein AC1, Protein AL1.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae Rep protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: RIMK_PASMU
Sequence: MKLLMLCREPRLYSCQRLKEAAENSGHQMDILDPNRCLLKLSENSPHFELIYQATMEHEPSRLLNYDAVIPRFGSQSTKMGCAVLRHFEAQNIPCLNSATAFLQARDKWQSLQMLMAQGIAIPHSLLAGPEFQAPSTMQYVQSPTILKTLSGAQGIGVILAEKRQSAVSILETLKQADVSVLAQEFIEEANGADLRCFVIGERVVASMQRISQNGEFRANFHRGGLAEKVSLSEAEKTMAVKATKALGLDVAGVDLIRAKRGTLVLEVNASPGLEMIEKTSGIDIALQMIVHLEKKYQALQNVTKTIELRSHK
What are the official names of this protein?
Probable alpha-L-glutamate ligase.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: RS2_ECOLU
Sequence: MATVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLEKTVPMFNEALAELNKIASRKGKILFVGTKRAASEAVKDAALSCDQFFVNHRWLGGMLTNWKTVRQSIKRLKDLETQSQDGTFDKLTKKEALMRTRELEKLENSLGGIKDMGGLPDALFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPGNDDAIRAVTLYLGAVAATVREGRSQDLASQAEESFVEAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: CLC10_RAT
Sequence: MTMAYENFQNLGSEEKNQEAGKAPPQSFLCNILSWTHLLLFSLGLSLLLLVVISVIGSQNSQLRRDLETLRTTLDNTTSNTKAELQALASRGDSLQTGINSLKVEVDDHGQELQAGRGLSQKVASLESTVEKKEQTLRTDLSEITDRVQQLGKDLKTLTCQLASLKNNGSAVACCPLHWMEHEGSCYWFSQSGKPWPEADKYCQLENSNLVVVNSLAEQNFLQTHMGSVVTWIGLTDQNGPWRWVDGTDYEKGFTHWAPKQPDNWYGHGLGGGEDCAHFTSDGRWNDDVCQRPYRWVCEMKLAKDS
What is the function of this protein?
Recognizes terminal galactose and N-acetylgalactosamine units.
What are the official names of this protein?
C-type lectin domain family 10 member A, MMGL, Macrophage asialoglycoprotein-binding protein 1, M-ASGP-BP-1, Macrophage galactose/N-acetylgalactosamine-specific lectin.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: SUCC_HALMA
Sequence: MRLHEYQAKQVFADAGIPTPASQLAETVDEAVDAAEEIGYPVAIKAQVHVGGRGKAGGIKLVESKEEAREAAEDIIGMDLKGYHVSKVLVEEAVDFVNELYVGVTMDRGEGRPVAMVSTKGGVNIEEVAEEDPDAIAREHIDPAFGMHPFQARKVVYEAGVDREVANDVASVLTTLYQLWDDRDGADTEINPLMITSDDEVIAADAVMNVDGDALFRQPEIAEMGEEAAEGDELEQKADEYGFDYVRLDGNVGIIGNGAGLVMTTLDLVDYYDGEPANFLDVGGGAKADRIANALDMVFSDENVDSVVFNIFGGITRGDEVANGINQALEQFDEIPKPVTVRLAGTNAEEGMEILNEDLVTVEHTLEDAVQRAVEYAKEVEA
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: YBEY_NEIMA
Sequence: MKRTKKYPFLTLQRQRFHLNFENASSAAGIPAERDFYRWAWSALKSGYRRADISLILLDEEEARAYNRDYRGKDYATNVLSFALNEGEILPCQVSEKLYGDLIICPQVVLKEAAEQGKTPERHFAHLTIHGVLHLMGYDHIEDDEAEIMEAEEIRLMLAAGFPNPYQEDGH
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARP6_KLULA
Sequence: MSEPVLVIDNGSYEIKFGESGWDQPLRALNCLTKDKYSRFHLSNQTKKMRDISQALIRRPHELGQLVSWELESEVWDYCFYNEDDFHWNLTHDNDTKDHHLVVSETLMTIPELSKNMDQVIFEEYDFKSMFKGPVAQYIPFYQGQYQDDAMTAAEDKKTSSYKDFQLVIDSGFNCTWAVPIIKGVPYYKAIKKLDIGGRFLTGLLQETISFRHYNVMEETILVNNIKEQCTFVPPESYFSSFHNKMNTKVEYVLPDFQTSFLGYVKKPGKEKLTDDAQTLLLTDEVFSVPETFFHPEIAQILKPGIVETILECINMCPEVVRPLLVANIVCTGGNFNIPNFHERLQTELQRQCPIDWSCKVHSPQEKDKSLHGWESMKDFANSDQFRSARVTREEYLEHGLDWCTKNRFGYQQWL
What is the function of this protein?
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling.  Involved in chromosome stability (By similarity).
What are the official names of this protein?
Actin-like protein ARP6.
What is the protein family that this protein belongs to?
Belongs to the actin family. ARP6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Nucleus.
Protein: QAX_NEUCR
Sequence: MTSRTTTATELDEIYTFAVQLGKDAGNLLMEAARLRFSNNNANHDKESTTQEFTEKDSAVDIVTQTDEDVEAFIKSAINTRYPSHDFIGEETYAKSSQSTRPYLVTHTTPTWVVDPLDGTVNYTHLFPMFCVSIAFLVDGTPVIGVICAPMLGQLFTACKGRGAWLNETQRLPLVRQPMPKSAPGGCVFSCEWGKDRKDRPEGNLYRKVESFVNMAAEVGGRGGKGGMVHGVRSLGSATLDLAYTAMGSFDIWWEGGCWEWDVAAGIAILQEAGGLITSANPPEDWATAEIPDVKLGSRLYLVVRPAGPSEGETAREGQERTIREVWRRVRALDYTRPGA
What is the function of this protein?
Not known.  Probably involved in quinate metabolism.
What are the official names of this protein?
Protein QA-X.
What is the protein family that this protein belongs to?
Belongs to the inositol monophosphatase superfamily.
Protein: CH10_SALAR
Sequence: MSIRPLHDRVIVKRKEVESKSAGGIVLTGSAAGKSTRGEIIAVGKGRILDNGTVQPLDVKVGDIVIFNDGYGVKSEKIDNEEVLIMSESDILAIVEA
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPIR2_HUMAN
Sequence: MARAGSCGGAAAGAGRPEPWELSLEEVLKAYEQPLNEEQAWAVCFQGCRGLRGSPGRRLRDTGDLLLRGDGSVGAREPEAAEPATMVVPLASSEAQTVQSLGFAIYRALDWGLDESEERELSPQLERLIDLMANNDSEDSGCGAADEGYGGPEEEEEAEGVPRSVRTFAQAMRLCAARLTDPRGAQAHYQAVCRALFVETLELRAFLARVREAKEMLQKLREDEPHLETPRAELDSLGHTDWARLWVQLMRELRRGVKLKKVQEQEFNPLPTEFQLTPFEMLMQDIRARNYKLRKVMVDGDIPPRVKKDAHELILDFIRSRPPLKQVSERRLRPLPPKQRSLHEKILEEIKQERRLRPVRGEGWAARGFGSLPCILNACSGDAKSTSCINLSVTDAGGSAQRPRPRVLLKAPTLAEMEEMNTSEEEESPCGEVTLKRDRSFSEHDLAQLRSEVASGLQSATHPPGGTEPPRPRAGSAHVWRPGSRDQGTCPASVSDPSHPLLSNRGSSGDRPEASMTPDAKHLWLEFSHPVESLALTVEEVMDVRRVLVKAEMEKFLQNKELFSSLKKGKICCCCRAKFPLFSWPPSCLFCKRAVCTSCSIKMKMPSKKFGHIPVYTLGFESPQRVSAAKTAPIQRRDIFQSLQGPQWQSVEEAFPHIYSHGCVLKDVCSECTSFVADVVRSSRKSVDVLNTTPRRSRQTQSLYIPNTRTLDFK
What is the function of this protein?
Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament (PubMed:21620703).  Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport (By similarity).  Required for asymmetric spindle positioning and asymmetric cell division during meiosis (PubMed:21620703).  Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis (PubMed:21620703).  Also acts in the nucleus: together with SPIRE1 and SPIRE2, promotes assembly of nuclear actin filaments in response to DNA damage in order to facilitate movement of chromatin and repair factors after DNA damage (PubMed:26287480).
What are the official names of this protein?
Protein spire homolog 2, Spir-2.
What is the protein family that this protein belongs to?
Belongs to the spire family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Detected at the cleavage furrow during asymmetric oocyte division and polar body extrusion.
Protein: DPO4_MARMS
Sequence: MQNRKIIHIDADCFYAAIEMRDDPNLRDIPMAIGGPASGRSVLSTANYAARVYGVRSAMPTSVAKRLCPALLVIPGNMNKYRLASEQMHAIFREFTDIIEPLSLDEAYLDVTNSSSFQGSATRIAEEIRSRILKEVGITVSAGVATNKFIAKVASDWDKPDGLTVVTPEKQFEFVSNVPVKFISGIGRVAQEKLASLGVFKCSDLQALDFSVLQKSFGSMSFRLSQFALGIDDRPVTVSRERKSISVEHTFSKDLLDLKECQAVLPILLTDLKKRMSGRDFESQLSKYYLKVKFDDFKQTTIEQPIKAKLSDDVFSQLLQQAYSRSRRPVRLIGVGYRLSPPELHQLNLPFV
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCT5_CAEBR
Sequence: MGIFLGLVDSSSPKSSTSCSLMTSCAVEKCLNKDMVRKIVIESSREEVFGNLVEKFDMVCIAAKCGNECSQCKHCHYALEQMSALAQGEKTSGLCPKLETCVFNCLTEDVSKVLSCVATRCNVHCYDGDCPSCKMISRRIFSTICKQHSMTSQPQIKYEGTCPNLFMELADHYVAKKKL
What is the function of this protein?
Acts downstream of daf-16/foxo to suppress tumors induced by disruption of gld-1.  Potentially a direct target of daf-15/foxo (By similarity).
What are the official names of this protein?
Protein dct-5, Daf-16/foxo controlled, germline tumor affecting protein 5.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: GSTZ_EUPES
Sequence: MASVEQPNKPKLKLYSYFRSSCSFRVRIALNLKGLDYEYVPVNLLKGEQFTPEFLKINPIGYVPALVDGEDVISDSFAILMYLEEKYPEHPILPADIHKKAINYQAANIVSSSIQPLQNLAVLNFIGEKVSPDEKVPWVQRHISKGFAALEKLLQGHAGRFATGDEVYLADLFLEPQIHAAITRFNVDMTQFPLLLRLHEAYSQLPEFQNAMPDKQPDSTSPTAS
What are the official names of this protein?
Glutathione S-transferase zeta class.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Zeta family.
What are the subcellular locations of this protein?
Cytoplasm.