PharMolix/UniProtQA huggingface dataset:
Protein: RPOB_BAUCH
Sequence: MLYSYTEKKRIRKDFGKRSQVLDVPYLLSIQLESFQKFIERDNEGQHGLEAAFRSVFPIQSYSGNAELQYVSYHLGEPVFDVKECQTRGLTFSAPLRVILRLIIRDATTETPIKEQEVYMGEIPLMTENGTFVINGTERVIVSQLHRSPGVFFDSDKGKIHSSGKVLFNARIIPYRGSWLDFEFDQKDHLFVRIDRRRKLPATIILRALQLSTNQILDTFFEKVIFHLNDEHIQMELVPERLRGETASFDIIANGTIYVNKGRRITARHIHQLKIDSIDRINVPREYLVGKIIAIDYIHDNTGEIIVPANIEITLEILDKLGKANFKRIETLFTNDLDHGAYISETLRIDSTRDRLSALVEIYRMMRPGEPPTREAAENLFENIFFSEDRYDLSAVGRMKFNRALLREEIEGSGLLSKSDIIEVMKKLIDIRNGKGEVDDIDHLGNRRVRSVGEMAENQFRIGLVRVERAVKERLSLSDLESLMPQDIINAKPISAAIKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYAKTNEYGFLETPYRLVHNSVVTEEIHYLSAIEEGNFIIAQANTNLDDKGNFVEELVTCRHKGESGFFSREKVHYMDVSTQQIVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRTDKPLVGTGMERIVAVDSGVTVVAKRGGIVQYVDASRIVINVHSDEMYSGEAGIDIYHMTKYIRSNQNTCISQKPCVTLGELVERGNVLADGPSTDLGELALGQNMRIAFMPWNGYNFEDSMLVSERVVQKDCFTTIHIQELACMSRDTKLGPEEITSDIPNVGEAALCKLDESGIVYIGAEVTSGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGYSGTVIDVQIFTRDGVKKDKRTLEIEEMQLQQAKKDLTEERRIFEAALFTRIRHVLGSDITNIDIVKILKLKREDWSQFNIKDNNKYCQLEQLAEQYYELNKVFANKLEEKRRKITQGDDLSPGVLKIVKVYIAVKRQIQPGDKMAGRHGNKGVISKINPIEDMPYDEKGIPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINKMLKQHKNAEQLRQFIQKAYDIGDQVRQKVNLNLFSDQEILLLAENLKHGMPMATPVFDGAKEKEIKQMLQLAELPVSGQITLFDGRTGEPFERQVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDCNHTMEPAMPESFNVLLKEIRSLGINIELEKN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: ISPE_SALCH
Sequence: MMTHWPSPAKLNLFLYITGQRADGYHTLQTLFQFLDYGDTLHIEPRHDGEIHLLTPVNGVENEDNLIVRAARLLMKVASESGRLPAGSGADISIEKRLPMGGGLGGGSSNAATVLVALNHLWQCGLSIDELATLGLTLGADVPVFVRGHAAFAEGVGEILTPVNPPEKWYLVAPPGVSLPTPVIFKDPQLPRNTPKRSIDTLLKCEFSNDCEVIARKRFREVDAALSWLLEYAPSRLTGTGACVFAEFDTESCARQVLEQAPEWLNAFVAKGVNLSPLHRELL
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: RPOZ_PROMA
Sequence: MIKAGFDSKDLAKRGESLIRQASNRYLTTVRIAFRAKQRRFDDFDGLLEESSVKPVQRSIIELSDEQDQPDLLPG
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: PSRP_HAHCH
Sequence: MKRTAFFISDGTGITAEALGQSLLAQFEFIEFEKITLPYIDSLEKARKAVARIDKASEIDGNKPVIFDTIVNSEIRAEIRKSQGYMIDIFGTFLEPLEQELGSKSTYTVGKSHSIVSNSSYNRRIDAMNYALENDDGARVRYYNEADIILVGVSRSGKTPTCIYLALQYGIKAANFPLTEDDILDQRLPESLRSYREKIFGLTIDPERLAVIRNERKPNSKYASIKQCNYEVEEVELMYRRERIPYLNSTDYSVEEISTRIMMMTGIERHIR
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: VE2_HPV66
Sequence: METLSQRLDACQNKILDCYEKDSKCIIDHIDYWKAVRHEYVLYYKARENDINVLNHQMVPSLQVCKAKACSAIELQIALEAISNTIYKNEEWTLRDTCDELWRTEPKNCFKKEGQHIEVWFDGNKNNCMEYVVWKFIYYNGECGWCKVSSGVDYRGIYYMHDGHKTYYTDFEQEAKKYGCTNIWEVHMETESIYCPDSVSSTCRYNVPPVETVNEYNNHRTTTTASTFVGAQDAAVSHRPGKRPRASESEPDSSRESYAHCVTTDTDISNNANSRSPRINTQSHCGDKTTPVIHLKGEANRLKCCRYRFQKYKTLFTDVTTTYHWTSTDNKDSSIITILYKDETQRDTFLNVVKIPPSVQVILGQMSCP
What is the function of this protein?
Plays a role in the initiation of viral DNA replication.  A dimer of E2 interacts with a dimer of E1 in order to improve specificity of E1 DNA binding activity.  Once the complex recognizes and binds DNA at specific sites, the E2 dimer is removed from DNA.  E2 also regulates viral transcription through binding to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory regions of the viral genome.  Activates or represses transcription depending on E2RE's position with regards to proximal promoter elements including the TATA-box.  Repression occurs by sterically hindering the assembly of the transcription initiation complex.
What are the official names of this protein?
Regulatory protein E2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E2 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: AMPP2_ARATH
Sequence: MIPLTLSSPSLNRLVLSTSRYSHSLFLSNFNSLSLIHRKLPYKPLFGARCHASSSSSSSSSFTAKSSKEIRKAQTKVVVDEKLSSIRRLFSEPGVGIDAYIIPSQDAHQSEFIAECYARRAYISGFTGSAGTAVVTKDKAALWTDGRYFLQAEKQLNSSWILMRAGNPGVPTASEWIADVLAPGGRVGIDPFLFSADAAEELKEVIAKKNHELVYLYNVNLVDEIWKDSRPKPPSRQIRIHDLKYAGLDVASKLLSLRNQIMDAGTSAIVISMLDEIAWVLNLRGSDVPHSPVMYAYLIVEVDQAQLFVDNSKVTVEVKDHLKNAGIELRPYDSILQGIDSLAARGAQLLMDPSTLNVAIISTYKSACERYSRNFESEAKVKTKFTDSSSGYTANPSGIYMQSPISWAKAIKNDAELKGMKNSHLRDAAALAHFWAWLEEEVHKNANLTEVDVADRLLEFRSMQDGFMDTSFDTISGSGANGAIIHYKPEPESCSRVDPQKLFLLDSGAQYVDGTTDITRTVHFSEPSAREKECFTRVLQGHIALDQAVFPEGTPGFVLDGFARSSLWKIGLDYRHGTGHGVGAALNVHEGPQSISFRYGNMTPLQNGMIVSNEPGYYEDHAFGIRIENLLHVRDAETPNRFGGATYLGFEKLTFFPIQTKMVDVSLLSDTEVDWLNSYHAEVWEKVSPLLEGSTTQQWLWNNTRPLAKP
What is the function of this protein?
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro.
What are the official names of this protein?
Aminopeptidase P2, AtAPP2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SYS_MICLC
Sequence: MIDVKDLIEQPEKYRASQEARGEDASLVDRVVEADAARRSSIAGFEQLRAEQKAFGKRVAQAKGEEKQALLAEVKDLAARVKEAESAAGAAEARLAELQRAFPNLIVDGVPAGGEDDFVVLKEVGTPRDFAAEGFEPRDHLELGELLGAIDMERGAKVSGARFSFLTGVGARLELALMQLGLDLALENGFVPVIPPTLVRPETMQGTGFDVEHDDEIYRLERDDLYLVGTSEVALAGFHAGEIMDVSAPVRYAGWSTCYRREAGSAGKDTRGIIRVHQFNKLEMFIYAAQEDAEAEHARLLAWEERMLGAIEVPYRVIDIAAGDLGLSAARKFDCEAWVPTQGTYRELTSTSNCTTFQARRLNIRERVRTEDGSKGGTRMVATLNGTLATTRWIVAILENHQNADGSVTVPAALRPYLGGMERFELV
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATA_HALSA
Sequence: MSQAEAITDTGEIESVSGPVVTATGLDAQMNDVVYVGDEGLMGEVIEIEGDVTTIQVYEETSGIGPGQPVDNTGEPLTVDLGPGMLDSIYDGVQRPLDVLEDEMGAFLDRGVDAPGIDLDTDWEFEPTVEAGDEVAAGDVVGTVDETVSIEHKVLVPPRSDGGEVVAVESGTFTVDDTVVELDTGEEIQMHQEWPVRRQRPTVDKQTPTEPLVSGQRILDGLFPIAKGGTAAIPGPFGSGKTVTQQSLAKFADADIVVYIGCGERGNEMTEVIEDFPELPDPQTGNPLMARTTLIANTSNMPVAARESCIYTGITIAEYYRDMGYDVALMADSTSRWAEAMREISSRLEEMPGEEGYPAYLAARLSEFYERAGYFENFNGTEGSISVIGAVSPPGGDFSEPVTQNTLRIVKTFWALDSDLAERRHFPAINWDESYSLYKDQLDPWFTDNVVDDWAEQRQWAVDILDEESELEEIVQLVGKDALPEDQQLTLEVARYIREAWLQQNALHDVDRYCPPEKTYAILSGIKTLHEESFEALDAGVPVEEITSIDAAPRLNRLGTTPDDEHEAEVAEIKQQITEQLRELY
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The archaeal alpha chain is a catalytic subunit (By similarity).
What are the official names of this protein?
V-type ATP synthase alpha chain, V-ATPase subunit A.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: ARP2_CAEBR
Sequence: MDSQGRKVIVVDNGTGFVKCGYAGTNFPAHIFPSMVGRPIVRSTQRVGNIEIKDLMVGEECSQLRQMLDINYPMDNGIVRNWDDMGHVWDHTFGPEKLDIDPKECKLLLTEPPLNPNSNREKMFQVMFEQYGFNSIYVAAVLTLYAQGLLTGVVVDSGDGVTHICPVYEGFALHHLTRRLDIAGRDITKYLIKLLLQRGYNFNHSADFETVRQMKEKLCYIAYDVEQEERLALETTVLSQQYTLPDGRVIRLGGERFEAPEILFQPHLINVEKAGLSELLFGCIQASDIDTRLDFYKHIVLSGGTTMYPGLPSRLEKELKQLYLDRVLHGNTDAFQKFKIRIEAPPSRKHMVFLGGAVLANLMKDRDQDFWVSKKEYEEGGIARCMAKLGIKA
What is the function of this protein?
Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.  Seems to contact the pointed end of the daughter actin filament (By similarity).
What are the official names of this protein?
Actin-related protein 2, Actin-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the actin family. ARP2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: FBRL_CAEEL
Sequence: MGRPEFNRGGGGGGFRGGRGGDRGGSRGGFGGGGRGGYGGGDRGSFGGGDRGGFRGGRGGGDRGGFRGGRGGGDRGGFGGRGSPRGGFGGRGSPRGGRGSPRGGRGGAGGMRGGKTVVVEPHRLGGVFIVKGKEDALATKNMVVGESVYGEKRVSVDDGAGSIEYRVWNPFRSKLAASIMGGLENTHIKPGTKLLYLGAASGTTVSHCSDVVGPEGIVYAVEFSHRSGRDLLGVAKKRPNVVPIVEDARHPHKYRMLVGMVDVIFSDVAQPDQARIVALNAQNFLRNGGHAVISIKANCIDSTAEPEAVFAGEVNKLKEEKFKPLEQVTLEPYERDHAVVVAVYRPVKGKKV
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins (By similarity).  Involved in pre-rRNA processing.  Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA (By similarity).  Site specificity is provided by a guide RNA that base pairs with the substrate.  Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA (By similarity).  Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ105me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus (By similarity).  Plays a role in modulation of nucleolus size most likely through regulating the ribosomal RNA (rRNA) pool (PubMed:26492166).
What are the official names of this protein?
rRNA 2'-O-methyltransferase fibrillarin, Histone-glutamine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Fibrillarin family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Note=Fibrillar region of the nucleolus. Predominantly localizes to the nucleolus, but also localizes to small punctate structures throughout the nucleoplasm. Co-localizes with dao-5 in nucleoli.
Protein: GPDA_ANASK
Sequence: MRATVLGAGSWGTALASLLAGKGYTVTSWDKDAAVLDDIARNHRNERYLPGLQLPPTLHASGEVAKALEGAELVVLAVPSHAVRPVVIEAKRHVHAGTPIVCVAKGIELDTLMTMTEVVEDVLPVPLHPYLAVLSGPSFAKEVAKGLPTAVTVAARWERIAKQVQDAFHTKTFRPYTSGDVVGCEVGGCVKNVVAIAAGISDGMGFGANAMAALVTRGLAEITRLAVRKGANPLTLSGLAGLGDLVLTCSSDLSRNRTVGRGLAAGKTADAIQRELGQVAEGVRNARSARELAKRLGVDMPITEAIYRVLYEGLAPREAVTALMMRETKPEL
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLMA_ECO57
Sequence: MKLPRSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAAFMAYESGK
What is the function of this protein?
Toxic component of a type I toxin-antitoxin (TA) system (By similarity).  Part of the plasmid maintenance system, encodes a toxic protein that collapses the transmembrane potential and arrests respiration (By similarity).  When the adjacent non-translated flmB (sok) gene is disrupted FlmA no longer functions in plasmid maintenance (i. e.  FlmB probably encodes an antisense antitoxin RNA) (By similarity).  Translation of FlmA may be coupled to the upstream flmC gene (By similarity).
What are the official names of this protein?
Stable plasmid inheritance protein, F leading maintenance protein.
What is the protein family that this protein belongs to?
Belongs to the Hok/Gef family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RS7_RHOOB
Sequence: MPRKGPAPKRPLINDPVYGSPLVTQLVNKILLDGKKSTAERIVYEALEVAREKTGTDPVVTLKRALDNVKPALEVRSRRVGGATYQVPVEVRPGRSTTLALRWLVTFSRQRREKTMVERLANELLDASNGLGAAVKRREDTHKMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: G6PI_NOSS1
Sequence: MDAKALWQRYQEWLYFHEGLGLYLDVSRMRFDDAFVKSLLPKFDKAFADMAELEKGAIANPDENRMVGHYWLRNPDLAPTPEIAQEIVQTLEQIEAFAEKIQTGAIHPPKANRFTDIISIGIGGSALGPQFVAEALAPEFPPLKIHFIDNTDPAGIDRILTHLRNHLASTLVLVISKSGGTPEPRNGMIEVKKAYAGQNLDFAQYAVAITSTGSNLDKVAQSEGWLATFPMYDWVGGRTSEMSSVGLVPAALQGIDVRAMLEGAKEMDDATRVPEVKNNPAALLALSWYYSGNGKGEKDMVVLPYKDSLLLFSRYLQQLVMESLGKEKDLDGNTVYQGIAVYGNKGSTDQHAYVQQLREGVPNFFATLIEVLEDRHGASPEIDPGVTSGDYLSGFLLGTRQALYENQRDSITVTIPQVNARTVGALVALYERTVGLYASLVNINAYHQPGVEAGKKAAAVILDLQTKVVGLLQKEKTALSLEQIAEKIGAADQVEAIYKILRHLQANQRGVVFQGNLGQPSSLKISLS
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SALAT_PAPSO
Sequence: MATMYSAAVEVISKETIKPTTPTPSQLKNFNLSLLDQCFPLYYYVPIILFYPATAANSTGSSNHHDDLDLLKSSLSKTLVHFYPMAGRMIDNILVDCHDQGINFYKVKIRGKMCEFMSQPDVPLSQLLPSEVVSASVPKEALVIVQVNMFDCGGTAICSSVSHKIADAATMSTFIRSWASTTKTSRSGGSTAAVTDQKLIPSFDSASLFPPSERLTSPSGMSEIPFSSTPEDTEDDKTVSKRFVFDFAKITSVREKLQVLMHDNYKSRRQTRVEVVTSLIWKSVMKSTPAGFLPVVHHAVNLRKKMDPPLQDVSFGNLSVTVSAFLPATTTTTTNAVNKTINSTSSESQVVLHELHDFIAQMRSEIDKVKGDKGSLEKVIQNFASGHDASIKKINDVEVINFWISSWCRMGLYEIDFGWGKPIWVTVDPNIKPNKNCFFMNDTKCGEGIEVWASFLEDDMAKFELHLSEILELI
What is the function of this protein?
Involved in biosynthesis of morphinan-type benzylisoquinoline alkaloids.  Catalyzes the conversion of the phenanthrene alkaloid salutaridinol to salutaridinol-7-O-acetate, the immediate precursor of thebaine along the morphine biosynthetic pathway.  Conversion of 7-O-acetylsalutaridinol into thebaine is spontaneous.
What are the official names of this protein?
Salutaridinol 7-O-acetyltransferase, salAT.
What is the protein family that this protein belongs to?
Belongs to the plant acyltransferase family.
Protein: ATL47_ARATH
Sequence: MSERRIHYSQLKNDNLNQISPSSAPSPITLNHQLTDSSSSSSSGGNNRISPIILFIIVLLSVIFFICSILHLLVRYYLKKKRSNLSSSPNESNQNPEFSDSDTYQRQLQQLFHLHDSGLDQALIDALPVFLYKEIKGTKEPFDCAVCLCEFSEDDKLRLLPNCSHAFHIDCIDTWLLSNSTCPLCRGTLFSLGHQFEYPDFNFGFFAGDDGGGGVRVSPVQKPAENEIGKRVFSVRLGKFRSSNIVNNGEVVVGGGGETSSSSLDNRRCFSMGSYQYIVAESDLVVALCPNNEGLKNNKDVEGKKINMRSKGESFSVSKIWQWSNKRSKFPNNHPSETNLVVGGSSSSSSYVCSGSDGLSLNGRRFQGP
What are the official names of this protein?
RING-H2 finger protein ATL47, RING-type E3 ubiquitin transferase ATL47.
What is the protein family that this protein belongs to?
Belongs to the RING-type zinc finger family. ATL subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: FABH_BARHE
Sequence: MIRSVVRGIGGALPKKSLSNDDIAKFVETSDSWIVQRTGIRQRYIANEKETTVSLGVEAAQAALINAGLTIKDIDCIILATSTPNHTFPASAVEIQHALGMSHGFAFDIQAVCSGFIFALTTGDAYLRCGTAKRILVIGSDTFSRILDWQDRTTCVLFGDGAGAAVLEAQEIERGVASDHGILSTKLRSNGAYMDKLYVDGGPSTTQKTGYLRMEGREVFKYAVGMITDVVDECFAAAGMDSSQLDWFVPHQANKRIIEASAKKLGISIDKVVITVDRHGNTSAASVPLALTMAICDGKIKKGDLVMLEAMGGGFTWGAILIRW
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WDR91_MOUSE
Sequence: MAEAVERTDELVREYLLFRGFTHTLRQLDAEIKADKEKGFRVDKIVDQLQQLMQVYDLAALRDYWSYLERRLFSRLEDIYRPTINKLKTSLFRFYLVYTIQTNRNDKAQEFFAKQATELQNQAEWKDWFVLPFLPSPDTNPTFATYFSRQWADTFIISLHNFLSVLFQCMPVPVILNFDAECQRTNQVQEENEVLRQKLFALQAEIHRLKKEEQQQEEEAAALVQHKLPPYVSSMDRLGDSELALVCSQRPASLSQSPRVGFLSSLLPQSKKSPSRLSPAQGPPQAQSSAKKDSFSSQATKGKDSVPGAKDGKSLLSGPVPGEASWTHQRQRRLQDHGKERRELLSTSSSQSQCAERKPEVSGAEAEPCLELHMGPVEVLARVSTAGSEGDRPEQPFIVLSQEEYGEHHSSIMHCRVDCSGRRVASLDVDGVIKVWSFNPIMQTKASSISKSPLLSLEWATKRDRLLLLGSGVGTVRLYDTEAKKNLCEININDDMPRILSLACSPNGASFVCSAAAPSLTSQTDSSAPDIGSKGMNQVPGKLLLWDTKTMKQQLQFSLDPEPIAINCTAFNHNGNLLVTGAADGVIRLFDMQQHECAMSWKAHCGEVYSVEFSCDENAVYSIGEDRKFIQWNIHKSGLKVSESNLPSDATGPFVLSGYSGYKQVQVPRGRLFAFDSEGNYMLTCSATGGLIYKLGSEEKVLENCLSLGGHRAPVVTVDWSTAMDCGTCLTASMDGKIKLTTLLAHKL
What is the function of this protein?
Functions as a negative regulator of the PI3 kinase/PI3K activity associated with endosomal membranes via BECN1, a core subunit of the PI3K complex.  By modifying the phosphatidylinositol 3-phosphate/PtdInsP3 content of endosomal membranes may regulate endosome fusion, recycling, sorting and early to late endosome transport.  It is for instance, required for the delivery of cargos like BST2/tetherin from early to late endosome and thereby participates indirectly to their degradation by the lysosome (By similarity).  May play a role in meiosis (PubMed:27346680).
What are the official names of this protein?
WD repeat-containing protein 91.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR91 family.
What are the subcellular locations of this protein?
Early endosome membrane; Peripheral membrane protein. Late endosome membrane.
Protein: SYA_SHEWM
Sequence: MYQTTAALRSAFLEYFRTNGHQVVDSSSLVPVNDPTLLFTNAGMNQFKDVFLGEDKRSYTRATSSQRCVRAGGKHNDLDNVGYTARHHTFFEMLGNFSFGDYFKREAISFAWNFLTQELKLPKERLCVTIYETDDEAFDIWTKEIGVPAESLIRIGDNKGAPYASDNFWQMGDTGPCGPCSEIFYDHGDHIWGGRPGTPEEDGDRFIEIWNIVFMQYNRQASGEMLPLPKPSVDTGMGIERIAAIMQGVHSNYEIDIFQALIKKTAEILGVTDLENKSLRVISDHIRSCAFLIADGVMPSNEGRGYVLRRIIRRAVRHGNKLGATSSFFYKLVPTLIEVMGDAAKGLVETQAIVEKSLKAEEEQFARTLERGLGILDGALNELKGDVLDGETAFKLYDTYGFPVDLTADVCREREITVDEAGFEVAMAEQRSRAQAAGQFDTDYNDSLKIDEETHFSGYTELTAQGKVTAIYKAGESTDSLNAGEDAVIVLDSTPFYGESGGQCGDKGLLTAKGVEFDVKDTQKYGQAVGHQGTVNSGSISVGDTLEAIVDKKLRHRTELNHSVTHLLHAALRQLLGTHVTQKGSLVDAERLRFDFSHFEGVKPEELKAVEDLVNTQIRRNHKLSADVMDMDQAKERGAMALFGEKYTDEVRVVTMGDFSIELCGGTHVGRTGDIGLFKITSEGGIAAGVRRIEAVTGAAAMAYVAAQKAELDQAAALLKADSNSVVTKLKAQLDRTKLLEKELSQLKDKLAAATSADLAGEAKQVNGAKVLIKKLEGVDAGALRGLQDELKQKLGSGVVVLAIAGEAKVNLIVGVTKDLTAKVKAGELVASIAAQVGGKGGGRPDMAQAGGTEPEKLDGALEQVLPWLEERLA
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3844_BACCR
Sequence: MLEKTTRMNYLFDFYQSLLTQKQRSYMSLYYLDDLSLGEIAEEFDVSRQAVYDNIKRTEAMLEEYEEKLVLLQKFQERQRLVAKLKQLISEEEHVNEEMKQVVEAIEKLD
What is the function of this protein?
Might take part in the signal recognition particle (SRP) pathway.  This is inferred from the conservation of its genetic proximity to ftsY/ffh.  May be a regulatory protein.
What are the official names of this protein?
UPF0122 protein BC_3844.
What is the protein family that this protein belongs to?
Belongs to the UPF0122 family.
Protein: RBL_AMOTI
Sequence: TKASVGFKAGVKDYKLTYYTPDYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVVGEENQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFEGPPHGIQSERDKLNKYGRPLLGCTIKPKLGLSAKNYGRACYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEALYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKYHGMHFRVLAKALRMSGGDHIHAGTVVGKLEGEREMTLGFVDLLRDDYIEKDRSRGIFFTQDWVSMPGVIPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIREASKWSPELAAACEIWKAIKFEFEPVDKLDIKK
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HEMA_CDVA4
Sequence: MLSYQDKVGAFYKDNARANSSRLSLVTEDQGGRRPPYLLFVLLILLVGIMALLAITGVRFHQVSTSNMEFSRLLKEDMEKSEAVHHQVIDVLTPLFKIIGDEIGLRLPQKLNEIKQFILQKTNFFNPNREFDFRDLHWCINPPSKIKVNFTNYCDTIGIRKSIASAANPILLSALSRSRGDIFPPYRCSGATTSVGSVFPLSVSLSMSLISRTSEIINMLTAISDGVYGKTYLLVPDYLEGEFDTQKIRVFEIGFIKRWLNNMPLLQTTNYMVLPENSKAKVCTIAVGELTLASLCVDESTVLLYHDSNGSQGGILVVTLGIFGATPMDQVEEVIPVPHPSVEKIHITNHRGFIKDSIATWMVPALVSEKQEEQKNCLESACQRKSYPMCNQTSWEPFGGGQLPSYGRLTLPLDPSIDLQLNISFTYGPVILNGDGMDYYESPLLDSGWLTIPPKNGTVLGLINKASRGDQFTVIPHVLTFAPRESSGNCYLPIQTSQIMDKDVLTESNLVVLPTQNFIYVIATYDISRGDHAIVYYVYDPIRTISYTHAFRLTTKGRPDFLRIECFVWDDDLWCHQFYRFEADSTNSTTSVENLVRIRFSCNRSKP
What is the function of this protein?
Attaches the virus to cell receptors and thereby initiating infection.  Binding of H protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion.  The cellular receptor might be SLAM, and may explain the lymphotropism of the virus (By similarity).
What are the official names of this protein?
Hemagglutinin glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses hemagglutinin-neuraminidase family. Non-sialidase subfamily.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type II membrane protein. Host cell membrane; Single-pass type II membrane protein.