PharMolix/UniProtQA huggingface dataset:
Protein: ZFP91_MOUSE
Sequence: MPGETEEPRSPEQQDQEGGPAAAADAASEELRPGAAAAPAAPAETASSRVLRGGRDRGRTAAAAAAAAAAVSRRRKAEYPRRRRSSPSNRPPDGPGHQPAAAKPPSPAQGKKSPRLQCIEKLTTDKDPKEEKEDDSVLPQEVSITTTRASRSWRSSSRTSISRLRDSENTRSSRSKTGSLQLVCKTEPITDQLDYDVPEEHQSPGGISSDEEEEEEEEMLISEEEIPFKDDPRDETYKPHLERETPKPRRKSGKVKEEKEKKEIKVEVEVEVKEEENEIREDEEPPRKRGRRRKDDKSPRLPKRRKKPPIQYVRCEMEGCGTVLAHPRYLQHHIKYQHLLKKKYVCPHPSCGRLFRLQKQLLRHAKHHTDQRDYICEYCARAFKSSHNLAVHRMIHTGEKPLQCEICGFTCRQKASLNWHMKKHDADSFYQFSCNICGKKFEKKDSVVAHKAKSHPEVLIAEALAANAGALITSTDILGTNPEPLTQPADGQGLPLLPEPLGNSTAGECLLLEAEGMSKSYCSGTERVSLMADGKIFVGSGSSGGTEGLVMNSDILGATTEVLIEDTDSTGP
What is the function of this protein?
Atypical E3 ubiquitin-protein ligase that mediates 'Lys-63'-linked ubiquitination of MAP3K14/NIK, leading to stabilize and activate MAP3K14/NIK.  It thereby acts as an activator of the non-canonical NF-kappa-B2/NFKB2 pathway.  May also play an important role in cell proliferation and/or anti-apoptosis.
What are the official names of this protein?
E3 ubiquitin-protein ligase ZFP91, Penta Zf protein, RING-type E3 ubiquitin transferase ZFP91, Zinc finger protein 91 homolog, Zfp-91, Zinc finger protein PZF.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NU4LM_ALLTR
Sequence: MPSISINIILAFAAALLGMLMFRSHMMSSLLCLEGMMLSMFILSTLIISNTQLTMSFMMPIMLLVFSACEAAIGLALLVMVSNTYGLDYIQNLNLLKC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: HSLO_GEOMG
Sequence: MGNSTDSIITDYLVRVIARDGSIRALACVTTGLVGELCRRHGTWPTASAALGRAVTGGALMGALLKTGQRVALRFEGNGPLKNILVEADANGAVRGCVGNPEANPLREDGKLDVAAAIGQAGLLTVTKDLGLKEPYTGTVLLYTSEIAEDLAYYLTDSEQVPSAVGLGVFVEPDGAVAAAGGFLIQSLPPHNDEAVDRLMERIGAMPPVTELLRQGKSPEGLLEYLFEGIPYDTLEKRALAFVCSCSRERIERVLISLGRDDLASLLAEQGETEVTCEFCREHYHFGRDDLERLLAGISAM
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBT_CHLP8
Sequence: MTDRFQQLLASIKPVDMNLTSAVKAHLDDLTKPQGSLGRLEEIAMKYCIATGTSKPSLSKKKVFCFAGDHGVAAEGVSAFPAEVTPQMVYNMLGGGAAINVLSRHAGADLEVVDMGVNHDFAEHPMLRRCKVKHGSANMAEGPAMSIDETLQAIMAGAELAIEAREQGYELLATGEMGIANTTPATALYSVLLDMSVNAITGRGTGIDDERLHHKIAVIEKAIEVNRANLATPLEVLAALGGFEIAGICGLILGAASVGMPVVVDGFISSSAAVCAIKLSCKVSDYLFFSHLSNEQGHRAVMQKLGARPILDLDLRLGEGTGAAMAMQVIEASLKIYNEMATFSSAGVSGKND
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: HV05_CARAU
Sequence: MEFWLSWVFLVAILKGVQCEVQLVESGGGLIQPGGSLRLSCAASGFTVSSNYMSWVRQPPGKGLEWVSVIYSGGSTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAR
What are the official names of this protein?
Ig heavy chain V region 5A.
Protein: SYIC_MOUSE
Sequence: MVQQVPENISFPAEEEKILEFWSKHNCFQECLKQSKLRPKFTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIKGPEDVAKMGIAEYNKQCRAIVMRYSAEWKSTVTRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMPFSTACGTPLSNFESNQNYKDVQDPSVFVTFPLEEDENTSLVAWTTTPWTLPSNLALCVNPEIQYVKIKDVARGKLFILTEARLSALYKQESDYEILERFPGASLKGKKYKPLFDYFIKCKENGAFTVLVDHYVKDEEGTGVVHQAPYFGADDHRVCMDFNIIQKDSVPVCPVDASGCFTEEVTHFVGQYVKDADKNIIRMLKEQGRLLAAGTFTHSYPFCWRSDTPLIYKSVPSWFVRVEPMVDQLLKNNDLCYWVPEFVREKRFGNWLKEARDWAISRNRYWGTPIPLWVSEDLEEVVCIGSVAELEELSGTKISDLHRESIDHLTIPSRCGKAPLRRVSEVFDCWFESGSMPYAQVHYPFESKREFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLILASDGQKMSKRKKNYPDPVSIIDKYGADALRLYLINSPVVRAENLRFKEEGVRDVLKDVLLPWYNAYRFFIQNVFRLHKEEEVKFLYNEHTVRESPNITDRWVLSFMQSLLGFFETEMAAYRLYTVVPRLVKFVDILTNWYVRMNRRRLKGESGVEDCVMALETLFSVLLSLCRLMAPYTPFLTELMYQNLKLLIDPASLRDKDTLSIHYLMLPRVREELIDKKTENAVSRMQSVIELGRVIRDRKTIPIKYPLKEIVVIHQDPEALEDIRSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMVLGKRLKGAFKAVMMAIKRLSNEELERFQKSGSIVVEGHELHEEDIRLMYTFDQATGGTAQFEAHSDAQALVLLDVTPDQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYNAKSEGRYLNNVIESHTDFIFATIKAPLKPYPVPTSDNILIQEQTQLKGSELEITLTKGSCVPGPACAYVNLNICANGTEQGGVLLLENPKGDNQLNLVKLKTVVTSVFGVKNAKLSVFHGETEIQNQTDLLSLSGRTLCVTAGASPSPISSPSTLLCQYLNLQLLNAEPQECLTGTVGTLLLENPLGQNGLTHQGLVHEAAKVFGLRSRRLRLFLNETQTQEITEDIPMKTLNMKTVYVSVLPTTADG
What is the function of this protein?
Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA.
What are the official names of this protein?
Isoleucine--tRNA ligase, cytoplasmic, Isoleucyl-tRNA synthetase, IRS, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytosol.
Protein: TIG_GLUOX
Sequence: MQVTPTLNEGLKRAFTVVVPSADLQARRDARLAEVAKTIKLPGFRPGKVPASLVKQRYGESVNAELLEEAVNDATAKLFEEQKIRPAMQPKIEVVSAIEDGKDLEFKVETEVLPEIEVPDLSGLKLTRLGAKVSEETVDKALNDVARRSRKFETIEEDRPAAKGDVLCVDFVGKLDGTPFDGGTADDVNVEIGGEGFIPGFAEQMEGMKAGEERVINVTFPADYQAEELAGKAVTFDIKAKSLKKAVDPAIDDELAKTIGFENLEQIRKIITEQAEGEYQQLSRLRIKRDLLDALSEKTDFEAPSSMVDAEFNQIWARVEEDRKVGRLDEEDAGKDEETLKADYRRIAERRVKLGLLLAEIGRKQEIQVSREELLGAMQQEARRYPGQEQMVFEFFSKNPQAVEGLRGPILENKVVDYLIELADVTDKEVTPEELAEIPPAEL
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: BL1S6_HUMAN
Sequence: MSVPGPSSPDGALTRPPYCLEAGEPTPGLSDTSPDEGLIEDLTIEDKAVEQLAEGLLSHYLPDLQRSKQALQELTQNQVVLLDTLEQEISKFKECHSMLDINALFAEAKHYHAKLVNIRKEMLMLHEKTSKLKKRALKLQQKRQKEELEREQQREKEFEREKQLTARPAKRM
What is the function of this protein?
Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes.  In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.  The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension.  May play a role in intracellular vesicle trafficking, particularly in the vesicle-docking and fusion process.
What are the official names of this protein?
Biogenesis of lysosome-related organelles complex 1 subunit 6, BLOC-1 subunit 6, Pallid protein homolog, Pallidin, Syntaxin 13-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the BLOC1S6 family.
Protein: LSPA_SHIF8
Sequence: MSQSICSTGLRWLWLVVIVLIIDLGSKYLILQNFALGDTVPLFPSLNLHASAYYGAAFSFLADSGGWQRWFFAGIAIGISVLLAVMMYRSKATQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYVGDWHFATFNLADTAICVGAALIVLEGFLPSKAKKQ
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATG12_PHANO
Sequence: MSAQEERIPEDDDTTEAPLTMAASVVLTNLPRDASKALETAGSLNVQKITVRLHPIGSAPALTQRVFKLSTNQRFDTIVRFLRKRLGVKEHESVFCYVGSVFAPGLDEGVGGLWSGEELVVGYAMAPAFG
What is the function of this protein?
Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.  Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function.  The ATG12-ATG5 conjugate functions as an E3-like enzyme which is required for lipidation of ATG8 and ATG8 association to the vesicle membranes (By similarity).
What are the official names of this protein?
Ubiquitin-like protein ATG12, Autophagy-related protein 12.
What is the protein family that this protein belongs to?
Belongs to the ATG12 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: PEPT_STRSY
Sequence: MKYPTLLDRFLVYVKENTRSDENSTTTPSTQNQVEFAQNILLPEMERIGLQNVHYLPNGFAVGTLPANDPSLTRKIGFIAHMDTADFNAEGVNPQIIENYDGNPIALGTSGYELHPKDFPQLANYHGQILITTDGTTLLGSDDKSGIAEIMTAIEFLIQNPDIKHCEIRVGFGPDEEIGVGADKFDVKDFDVDFAYTMDGGPLGELQYETFSAAGAKIDFLGRNVHPGSAKDQMINAFQMAIDFHNALPETDRPEKTEGYEGFFHLMNMEGSVDTASTTYIIRDFEEEDFQARKQLMLDIAEKMNANFDTPRVIVNLHDQYYNMKKIIEKDMTPINIAKDVMENLGIKPLIEPVRGGTDGSKISFMGIPTPNIFAGGENMHGRFEFVSLETMEKAVDVILGIVAYK
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBK_PROMM
Sequence: MAAFTLDLMAQLPEAYQAYAPAVDVLPLIPIFFFLLVFVWQASVGFR
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein K, PSII-K.
What is the protein family that this protein belongs to?
Belongs to the PsbK family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: METW_YEAST
Sequence: MTEIEFGQPLPSNLDYAVSFGIPTWDSAIGYAEKVPEVIGKMATGYPRYFPQPPVQRLCAYFVKKFGRGSENCRPFPSVNLGLKCFEYVKSVSGPESKAHLEVETVTIKNRGAKTSKEPAELVLTIAAVLASEEEFETVKEYWKLRGECVSSRLALSVNQLLDCANHGSEQVLRELEAGVFAAKKGEEKAKNLIKGRIVENRFRPFGLEKKTPNWEGLNLNPNEDVYLVSSGMSAISTARNLLTFWEEKKNSGDSLNKTTSDQKKKPLLCDTVGIFGFPFKDTQVIMTKFGKCKFFGFGNSRDVVELQKFLETSKQRILAVFVETPSNPLLNMPDLKKLRSLADQYGFFIVIDDTIGGLNVDILPYADIVSTSLTKLFNGASNVMGGSVVLNPKSSLYPYAREYFRSANFEDLLWCEDAIVLERNSRDFEDRTLRANANTGILLNDLLLPEEGKICKKIYYPTVTSKETFENYESVRNERGGYGCLFSVAFFNEGDAKAFYDSLKVFKGPSNGTNFTLACPYVHLAHHSELEEVSKFGADPNIIRVSVGLEDIQWLLKVFSSALDVVKSRGSKHS
What is the function of this protein?
Plays a role in inorganic sulfur assimilation during sulfur-limited conditions; catalyzes the conversion of O-acetyl-L-homoserine (OAH) into homocysteine in the methionine biosynthesis pathway (PubMed:36455053, PubMed:36379252).  Also catalyzes the conversion of O-acetylserine (OAS) into cysteine, the last step in the cysteine biosynthesis pathway (PubMed:36455053).  However, it seems that in S. cerevisiae cysteine biosynthesis occurs exclusively through the cystathionine pathway and not via direct incorporation of sulfur into OAS (By similarity).  It therefore has no metabolic role in cysteine biosynthesis and may only have a regulatory role controlling OAS levels (By similarity).
What are the official names of this protein?
Homocysteine/cysteine synthase, Hydrogen sulfide utilizing 1, O-acetylserine/O-acetylhomoserine sulfhydrylase, OAS-OAH SHLase, OAS-OAH sulfhydrylase.
What is the protein family that this protein belongs to?
Belongs to the trans-sulfuration enzymes family. MET7 subfamily.
Protein: IL5_CAVPO
Sequence: MRVLLQLGLLALGAVCVCAIPKQSATLRALVRETLTLLSTHRTLLKGNETLRISVPAHKNHQLCIEEIFQGIDTLKNQTTQGEALATLFQNLSLIKKHIDLQKQKCGEERRRVKQFLDYLQEFLAVINTEWTIEG
What is the function of this protein?
Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils.  Acts also on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation (By similarity).  Mechanistically, exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB.  Binding to the receptor leads to activation of various kinases including LYN, SYK and JAK2 and thereby propagates signals through the RAS-MAPK and JAK-STAT5 pathways respectively (By similarity).
What are the official names of this protein?
Interleukin-5, IL-5, Eosinophil differentiation factor, T-cell replacing factor, TRF.
What is the protein family that this protein belongs to?
Belongs to the IL-5 family.
What are the subcellular locations of this protein?
Secreted.
Protein: DAPA_STAAN
Sequence: MTHLFEGVGVALTTPFTNNKVNLEALKAHVNFLLENNAQAIIVNGTTAESPTLTTDEKERILKTVIDLVDKRVPVIAGTGTNDTEKSIQASFQAKALGADAIMLITPYYNKTNQRGLVKHFEAITDAVKLPVVLYNVPSRTNMTIEPETVEILSQHPYIVALKDATNDFEYLEEVKKRIDTNSFALYSGNDDNVVEYYQRGGQGVISVIANVIPKEFQALYDAQQSGLDIQDQFKPIGTLLSALSVDINPIPIKALTSYLEFGNYELRLPLVSLEDTDTKVLREAYDTFKAGENE
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EMRA_ECOLI
Sequence: MSANAETQTPQQPVKKSGKRKRLLLLLTLLFIIIAVAIGIYWFLVLRHFEETDDAYVAGNQIQIMSQVSGSVTKVWADNTDFVKEGDVLVTLDPTDARQAFEKAKTALASSVRQTHQLMINSKQLQANIEVQKIALAKAQSDYNRRVPLGNANLIGREELQHARDAVTSAQAQLDVAIQQYNANQAMILGTKLEDQPAVQQAATEVRNAWLALERTRIISPMTGYVSRRAVQPGAQISPTTPLMAVVPATNMWVDANFKETQIANMRIGQPVTITTDIYGDDVKYTGKVVGLDMGTGSAFSLLPAQNATGNWIKVVQRLPVRIELDQKQLEQYPLRIGLSTLVSVNTTNRDGQVLANKVRSTPVAVSTAREISLAPVNKLIDDIVKANAG
What is the function of this protein?
Part of the tripartite efflux system EmrAB-TolC, which confers resistance to antibiotics such as CCCP, FCCP, 2,4-dinitrophenol and nalidixic acid.  EmrA is a drug-binding protein that provides a physical link between EmrB and TolC.
What are the official names of this protein?
Multidrug export protein EmrA.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein; Periplasmic side.
Protein: NUOK_PSEAE
Sequence: MNAIPLEHGLALASVLFALGLVGLMVRRNILFVLMSLEVMMNAAALAFVVAGSRWGQPDGQVMFILVLSLAAAEASIGLAILLQLYRRFHTLDIDAASEMRG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VM39_DRYCN
Sequence: MIEVLLVTICFTVFPYQGSSIILESGNVNDYEVVYPQKVPALPKGGVQNPQPETKYEDTMQYEFHVNGEPVVLHLERNKGLFSEDYTETHYAPDGREITTSPPVQDHCYYHGYIQNEADSSAAISACDGLKGHFKHRGETYFIEPLKLSNSESHAIYKDEHVEKEDEIPKICGVTQTTSESDEPIEKISQLTNTPEQDRYLQVKKYIELYVVVDNRMYRNYNSNRDAINERVYEMVNTLNVMYRPLNFFIALIGLEIWSNQDEINIEPEVAVTLRSFGEWRNTTLLPRKRNDNAQLLTGIDFNGATVGLAYVGTLCRPTQSVAVIQDHSKRTSMVASTMAHELGHNLGINHDSASCNCNAGPCIMSATISNQPLSEFSSCSVQEHQRYLLRVRPQCILNKPLSTDIVTPPVCGNYFVERGEECDCGSPQDCQDACCNAATCKLQHDCDSGECCEQCKFKKAGAECRAAKDDCDLPESCTGQSAECPTDSFQRNGHPCQNNQGYCYNGKCPIMTNQCIALKGPGVNVSPDECFTLKQNDPECGFCRIENGTKIPCAEKDKMCGKLLCQEGNATCICFPTTDDPDYGMVEPGTKCGDGKVCINRQCVDVQTAY
What is the function of this protein?
Snake venom zinc metalloproteinase that may impair hemostasis in the prey.
What are the official names of this protein?
Zinc metalloproteinase-disintegrin-like MTP9, Snake venom metalloproteinase, SVMP.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-III subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RPIA_STRP8
Sequence: MEALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRVKQEGLQVVGVTTSSVTSKQAEVLGIPLKSIDDIDSIDLTVDGADEVDKDFNGIKGGGAALLMEKIVATPTKEYIWVVDASKMVEHLGAFKLPVEVVQYGADRLFRVFEKAGYKPSFRMKGDSRLVTDMQNYIIDLDLGCIKDPVAFGHLLDGTVGVVEHGLFNGMVDKVIVASKDGVTVLEAPKAG
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: RS8_PROM9
Sequence: MSNHDPISDMLTRIRNASQKKHTTTTIPGSKMSLSIAKVLQKEGFISDINEEGEGYKSQIILSLKYSGKNKFPTIRSMQRVSKPGLRIYKNTRGLPKVLGGLGVAIISTSKGVMSDRDARKQGIGGEVLCYVY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RPAP2_HUMAN
Sequence: MADFAGPSSAGRKAGAPRCSRKAAGTKQTSTLKQEDASKRKAELEAAVRKKIEFERKALHIVEQLLEENITEEFLMECGRFITPAHYSDVVDERSIVKLCGYPLCQKKLGIVPKQKYKISTKTNKVYDITERKSFCSNFCYQASKFFEAQIPKTPVWVREEERHPDFQLLKEEQSGHSGEEVQLCSKAIKTSDIDNPSHFEKQYESSSSSTHSDSSSDNEQDFVSSILPGNRPNSTNIRPQLHQKSIMKKKAGHKANSKHKDKEQTVVDVTEQLGDCKLDSQEKDATCELPLQKVNTQSSSNSTLPERLKASENSESEYSRSEITLVGISKKSAEHFKRKFAKSNQVSRSVSSSVQVCPEVGKRNLLKVLKETLIEWKTEETLRFLYGQNYASVCLKPEASLVKEELDEDDIISDPDSHFPAWRESQNSLDESLPFRGSGTAIKPLPSYENLKKETEKLNLRIREFYRGRYVLGEETTKSQDSEEHDSTFPLIDSSSQNQIRKRIVLEKLSKVLPGLLVPLQITLGDIYTQLKNLVRTFRLTNRNIIHKPAEWTLIAMVLLSLLTPILGIQKHSQEGMVFTRFLDTLLEELHLKNEDLESLTIIFRTSCLPE
What is the function of this protein?
Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes.  Recognizes and binds phosphorylated 'Ser-7' of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of 'Ser-5' of the CTD, thereby promoting transcription of snRNA genes (PubMed:17643375, PubMed:22137580, PubMed:24997600).  Downstream of EIF2AK3/PERK, dephosphorylates ERN1, a sensor for the endoplasmic reticulum unfolded protein response (UPR), to abort failed ER-stress adaptation and trigger apoptosis (PubMed:30118681).
What are the official names of this protein?
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2, RNA polymerase II-associated protein 2.
What is the protein family that this protein belongs to?
Belongs to the RPAP2 family.
Protein: AMP2_TITDI
Sequence: KDGYLVGNDGCKYSCFTRPGTYCANECSRVKGKDGYCYAWMACYCYSMPNWVKTWNRATNRCGR
What is the function of this protein?
Shows antibacterial activity against both Gram-positive bacteria (B. subtilis, M. luteus, E. faecalis) and Gram-negative bacteria (P. aeruginosa, Y. enterocolitica, A. calcoaceticus).  Modifies membrane sodium permeability on Y. enterocolitica.  Is toxic to mice, but is not to crabs.  Induces concentration dependent haemolysis in human erythrocytes (PubMed:19540868).  Acts by inhibiting the sodium (Nav) currents (By similarity).
What are the official names of this protein?
Bactridin-2, Bact2, Bactridine 2, P-Mice-Antm-beta* NaTx14.8.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NADD_CLAM3
Sequence: MTTPAAPRLRIGVMGGTFDPIHNGHLVAASEVQQHLQLDEVIFVPTGQPWQKQTVTDGEHRYLMTVIATAANPRFTVSRVDIDRAGTTYTIDTLRDIRRTHPDAELFFITGADAIQQILGWKDVAELWDLAHFVAVTRPGHDLTESGLPHADVRLLEVPALAISSTDCRARVGRGFPVWYLVPDGVVQYISKHHLYRSPQ
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: ADC_CHRVO
Sequence: MKQQEVRQRAFAMPLTSPAFPPGPYRFVNREYMIITYRTDPAAIEAVLPEPLQMAEPVVRYEFIRMPDSTGFGDYSESGQVIPVTFRGERGSYTLAMFLDDQPPLAGGRELWGFPKKAGKPRLEVHQDTLVGSLDFGPVRIATGTMGYKYEALDRSALLASLAEPNFLLKIIPHVDGSPRICELVRYHTTDVAIKGAWSAPGSLELHPHALAPVAALPVLEVLSARHFVCDLTLDLGTVVFDYLRQ
What is the function of this protein?
Catalyzes the conversion of acetoacetate to acetone and carbon dioxide.
What are the official names of this protein?
Acetoacetate decarboxylase, AAD, AADase, ADC.
What is the protein family that this protein belongs to?
Belongs to the ADC family.
Protein: RF1_SHESM
Sequence: MKESVIRKLEGLLERNEEVLALLGDASVIADQERFRALSKEYSQLEEVVAGFKAYQQALADLESAKEMLEEDDAEMREMAQEEIKAAKAELERLEAELQILLLPKDPNDDTNAFIEIRAGAGGDEAAIFAGDLFRMYSRYAEANRWQLEIMSSNEGEHGGFKEIIVKVSGEGAYGKLKFESGGHRVQRVPETESQGRVHTSAVTVVVMHEVPEAEAISINPADLKVDTFRSSGAGGQHVNKTDSAIRITHIPTGIVVECQDQRSQHKNRAQAMSVLAARIQAVEDEKRRSAEESTRRSLVASGDRSERVRTYNFPQGRVSEHRINLTLYRLNEVMEGDLDAILGPLMQEHQADLLAALADEQG
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.