PharMolix/UniProtQA huggingface dataset:
Protein: HCAD_ECO55
Sequence: MKEKTIIIVGGGQAAAMAAASLRQQGFTGELHLFSDERHLPYERPPLSKSMLLEDSPQLQQVLPANWWQENNVHLHSGVTIKTLGRDTRELVLTNGESWHWDQLFIATGAAARPLPLLDALGERCFTLRHAGDAARLREVLQPERSVVIVGAGTIGLELAASATQRRCKVTVIELAATVMGRNAPPPVQRYLLQRHQQAGVRILLNNAIEHVVDGEKVELTLQSGETLQADVVIYGIGISANEQLAREANLDTANGIVIDEACRTCDPAIFAGGDVAITRLDNGALHRCESWENANNQAQIAAAAMLGLPLPLLPPPWFWSDQYSDNLQFIGDMRGDDWLCRGNPETQKAIWFNLQNGVLIGAVTLNQGREIRPIRKWIQSGKTFDAKLLIDENIALKSL
What is the function of this protein?
Part of the multicomponent 3-phenylpropionate dioxygenase, that converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid-dihydrodiol (CI-dihydrodiol), respectively.
What are the official names of this protein?
3-phenylpropionate/cinnamic acid dioxygenase ferredoxin--NAD(+) reductase component.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase ferredoxin reductase family.
Protein: HSLU_ECO5E
Sequence: MSEMTPREIVSELDKHIIGQNNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAKNNWGQTEQQQEPSAARQAFRKKLREGQLDDKEIEIDLAAAPMGVEIMAPPGMEEMTSQLQSMFQNLGGQKQKARKLKIKDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKRGESSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLERLMEEISYDASDLSGQNITIDADYVSKHLDALVADEDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Heat shock protein HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTHS_ROSCS
Sequence: MRSDLDIAQAARLRPIRAVAADLGLTDDDIELYGRSIAKIDLGILQRLTDQPRGRYIVVTAITPTPLGEGKTTTTIGLGQALARLGKRSVVTIRQPSMGPTFGIKGGAAGGGYSQVLPMEQFNLHLTGDIHAIGAAHNLLAAMIDNHLHHGNQCGIDPYAIFWSRVVDISDRVLRNVVVGLGKKEDGPMRQTQFDITVASEVMAILALTTNLHDLRQRLGRIVAAYTRDGAPVTAEDLHAAGAMTVLLKEAIKPNLLQTLEGSPALVHCGPFANIAHGASSVLADMIGLHCADYVVTESGFGADIGFEKFCDIKCRASGLAPDAVVLVATVRALKAHSGRYTITAGRPLDPRLAEENPEDVADGAANLAAQVRIARLFGRPVVVAINRFPDDFPSEVEVIRQVARESGAFDVVESFVFAEGGAGGCDLARAAIQACEAPGTFTPLYPLDMSLREKIETLATKVYGATRVEYTPEASRRLAQFEHQGYGNLPICMAKTHLSISHDPKLRGAPSGYVFPIRDVRLAAGAGFIYPLAGDIRTMPGLPAHPAAERIDIDAEGRTRGLS
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: MRAZ_STAS1
Sequence: MFMGEYEHQLDTKGRMIVPSKFRYDLNERFIITRGLDKCLFGYTLEEWQVIEEKMKTLPMTKKDARKFMRMFFSGAVEVELDKQGRINIPQNLRQYANLSKECTVIGVSNRIEIWDRETWSSFYDESEESFEDIAEDLIDFDF
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: BASI_RABIT
Sequence: MAAVLFALLALALLRAGGASAAAGTVTTSVQSGDSWVQLTCTLNTSAAGVTGHRWLKGKEVVKEDQLQGLHTEHNVTGDDRFGKYSCLFLPKDTGEATLTVDGPPRIKAVKKSEHANEGDSVTLLCKSESFPFVTAWVWYKVADSGDQVIQNGSQSRFFISHSEAQSELHIKDLDLTSDPGEYACNGTSLQGTDAAVVTLRVRSRLAALWPFLGIVAEVLVLVTVIFIYEKRRKPDEVLDDEDAGAAPLKSSGHHVNDDKGKNVRQRNAS
What is the function of this protein?
Signaling receptor for cyclophilins, essential for PPIA/CYPA and PPIB/CYPB-dependent signaling related to chemotaxis and adhesion of immune cells (By similarity).  Plays an important role in targeting the monocarboxylate transporters SLC16A1/GLUT1, SLC16A3, SLC16A8, SLC16A11 and SLC16A12 to the plasma membrane (By similarity).  Acts as a coreceptor for vascular endothelial growth factor receptor 2 (KDR/VEGFR2) in endothelial cells enhancing its VEGFA-mediated activation and downstream signaling (By similarity).  Promotes angiogenesis through EPAS1/HIF2A-mediated up-regulation of VEGFA and KDR/VEGFR2 in endothelial cells (By similarity).
What are the official names of this protein?
Basigin.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single- pass type I membrane protein. Basolateral cell membrane; Single-pass type I membrane protein.
Protein: RS6_MESH7
Sequence: MPKYEIMTILDPKAEMAIIDNLLKTVFGDNSTEKLRKLETTNLAYPIRKSKIAQYFLVELNAPTNLIEEFVRRANITREIWRYLIVNLDSEKGLNKKPKIRERNRKYTPRRDRFDKPNFRGNPKSRFDQQDQQATKNQQNFQQNQQNQTSQYRENSRQNQDDFQQVSSNQQNFRQNQQNQSGYHRENNRQNQENIHQNNKNHQNQTSQTQRSRRQYQPIKNPKFNQKEKENYNNKKPQSSN
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: PYRR_BACCL
Sequence: MQKAVVMDEQAIRRALTRIAHEIIERNKGIDGCVLVGIKTRGIYLARRLAERIEQIEGASVPVGELDITLYRDDLTVKTDDHEPLVKGTNVPFPVTERNVILVDDVLFTGRTVRAAMDAVMDLGRPARIQLAVLVDRGHRELPIRADFVGKNVPTSRSELIVVELSEVDGIDQVSIHEK
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: BH168_ARATH
Sequence: MERAREIGEGSASSLREQRNLREKERRMRMKHLFSILSSHVSPTRRLPVPQLIDQAVSYMIQLKEKVNYLNEMKRRMLGGEVKNRSEGSSLLPKLSIRSLDSIIEMNLVMDLNMKGVMLHKLVSVFEEEGAQVMSANLQNLNDRTFYTIIAQAIICRIGIDPSRIEERLRDIIS
What are the official names of this protein?
Transcription factor bHLH168, Basic helix-loop-helix protein 168, AtbHLH168, bHLH 168, bHLH transcription factor bHLH168.
What is the protein family that this protein belongs to?
Belongs to the bHLH protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPG_STRS7
Sequence: MAGSLSEIKAKIISTEKTSKITSAMRMVSSAKLVKSEQAARDFQIYASKIRQITTDLLKSDLTTGSDNPMLVSRPVKKTGYIVITSDKGLVGGYNSKILKSIMDMIQEYHAAGDYEIISIGSIGSDFFKARGMNVAFELRGLADQPSFDQVGRIISQSVGMFVNEIFDELYVCYNHHVNSLTSQVRVQRMLPISDLVAEEAAEEGVTGFELEPNRHVILEQLLPQFTESLIYGAIIDAKTAEHAAGMTAMQTATDNAKHVINDLTIQYNRARQAAITQEITEIVAGANALE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RDRP_PLRVW
Sequence: MNRFTAYAALFFIFSLCSTAKEAGFQHPAFNFRGTSTMSALSGDYSAAPTPLYKSWALPSSLNLTTQPPPLLTDRSYYELVQALISKMRLDCQTVGDMTWRHLSEMLFASWNSVKEVSLKAASVTLWAIISIWFGLYWTLARLITLFLWTFSIEALCLILLGCITSLIYKGALSLSEHLPVFLFMSPLKIIWRAAFSKRNYKNEKAVEGYKGFSVPQKPPKSAVIELQHENGSHLGYANCIRLYSGENALVTAEHCLEGAFATSLKTGNRIPMSTFFPIFKSARNDISILVGPPNWEGLLSVKGAHFITADKIGKGPASFYTLEKGEWMCHSATIDGAHHQFVSVLCNTGPGYSGTGFWSSKNLLGVLKGFPLEEECNYNVMSVIPSIPGITSPNYVFESTAVKGRVFSDETVKELEREASEAVKKLARFKSLTGKNWANDYDSDEDYGLEKEAATNAPAEKTAQTNSAEKTAPSTSAEKTAPTNKPFKWASGTARQNKRQLRHPRRRYKRTTNGQNGRTDHHSYGGENQSLGDRGEDSEQGVSESPAEAQTKQTRKTWREEQAKQFTSYFDAIYKWGAQEEGCPPGFRKCGNIPGYYHPRTKGETKWGQKLCQVHPELADKTAGFGWPKAGFEAELQSLNLQAARWLQRAESATIPGAEARKRVIEKTVEAYRNCITNAPLCSLKSKLDWAGFQQDIREAVQSLELDAGVGIPYIAYGLPTHRGWVEDHKLLPVLTQLTFDRLQKMSEASFEDMSAEELVQEGLCDPIRLFVKGEPHKQSKLDEGRYRLIMSVSLVDQLVARVLFQNQNKREISLWRSVPSKPGFGLSTDTQTAEFLECLQKVSGAPSVEELCANHKEHTRPTDCSGFDWSVAYWMLEDDMEVRNRLTFNNTQLTERLRAAWLKCIGNSVLCLSDGTLLAQTVPGVQKSGSYNTSSSNSRIRVMAAYHCGADWAMAMGDDALEAPNSDLEEYKTLGFKVEVGRELEFCSHIFRNPTLAVPVNTNKMLYKLIHGYNPECGNPEVIQNYLAAVFSVLQELRHDRELVAKLHQWLVPSATTKEH
What is the function of this protein?
Precursor from which the RNA-dependent RNA polymerase (RdRp) is probably released.  RNA-dependent RNA polymerase plays an essential role in virus replication (Potential).
What are the official names of this protein?
Protein P1-P2.
What are the subcellular locations of this protein?
[Protein P1-P2]: Membrane; Multi- pass membrane protein.
Protein: CL004_RAT
Sequence: MKKNRERFSSKEREFVYKFQIGSERLELRVPLRFPVDENASHLHGRLMLLHSLPCFIENDLKEALARFIEEESLRDHDSDAEACLEAVKSGEVDLHQLASTWAKAYAETTLEHARPEEPNWDEDFADVYHDLIHSPASETLLNLEHNYFVSISELIGERDVELKKLRERQGIEMEKVMQELGKSLTDQDVNSLAAQHFESQQDLENKWSNELKQSTAIQKQEYQEWVIKLHQDLKNPNNSSLSEEIKVQPSQFRESADAAGRIYEEQRKLEESFTIHLGAQLKTMHNLRLLRADMLDFCKHKRTQGSGVKLHRLQTALSLYSTSLCGLVLLVDNRINSYSGIKRDFATVCQECTDFHFPRIEEQLEVVQQVALYARTQRRSKCKEARDSGNQNGGSDEKSKNAERNYLNILPGEFYITRHSNLSEIHVAFHLCVDDNVKSGNITARDPAIMGLRNILKVCCTHDITTISIPLLLVHDMSEEMTIPWCLRRAELVFKCVKGFMMEMASWDGGISRTVQFLVPQSISEEMFYQLSNMLPQIFRVSSTLTLTSKH
What is the function of this protein?
Plays a role in mast cell degranulation.
What are the official names of this protein?
Protein C12orf4 homolog.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPO4_DEHM1
Sequence: MAIRRVMHVDLDAFFVSVEQSLRPELKSKPVIVGGKPERRGVVAAASYEARKFGIHSGMPLLSAKHLCPQAVFIEGNHRLYREYSEKFMQILSDFSPFLEPMGLDEAYLEVTGFESLHGSIGEMALKIRRRITAELSINASIGIANSKVVAKIATERAKPNGQCEVPAGEEAAFLAPLDISIMPGIGKKTEYHLKSLGINTLGRLAGIPATFLKIHLGTYAPYLLNAAAGIDNRPVEMPAEAKSISRETTFETDTRNHTFLEAKLGYLSEKIAATLRKRGKQARVVQIKIRFADFTTLTRQKHLNHPCSGNQEIFQTALKLMNGILDSDRRSVRLLGVGISDFCGPEKQLEIDPARARLEKLDASLDKIRQKYGFGSVQTGRTYKLKDLF
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANB_PAEAT
Sequence: MAPSNLPESTTPAEVPAPYGTGPAAAAQAASAAGRKPISRVRIHHLQQAKDNGEHFAMLTAYEQYTAEIFDQAGIEVLLVGDSASNNVYGNETSLPVTVDELLPLTRAVSRSAKRALIVADLPFGSYEVSPGQAVATGVRFLKEGLAHAVKIEGTAYYADTVRAMVQAGIPVMAHIGFTPQSEHSLGGYRVQGRGDDAQRLVDDAVALQDAGAFSVLMEMVPAETAAAVDAALRVPTVGIGAGKTTTGQVLVWQDMAGLRGGKMAKFVKQYADLRTTLSDAAAAYGEDVRSGQFPGPEHSF
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FER2_APHSA
Sequence: MATYKVTLINEEEGINAILEVADDQTILDAGEEAGLDLPSSCRAGSCSTCAGKLVSGAAPNQDDQAFLDDDQLAAGWVMTCVAYPTGDCTIMTHQESEVL
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
Ferredoxin-2, Ferredoxin II.
What is the protein family that this protein belongs to?
Belongs to the 2Fe2S plant-type ferredoxin family.
Protein: RL17_SALA4
Sequence: MRHRKSGRQLNRNSSHRQAMFRNMAGSLVRHEIIKTTLPKAKELRRVVEPLITLAKTDSVANRRLAFARTRDNEIVAKLFNELGPRFASRAGGYTRILKCGFRAGDNAPMAYIELVDRSEKTEAAAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: S41A2_MACFA
Sequence: MTNSKGRSITDKTSGGPSNGGGFVDWTLRLNTIQSDKFLNLLLSMVPVIYQKNQEDRHKKANGIWQDGLSTAVQTFSNRSEQHMEYHSFSEQSFHANNGHASSSCSQKYDDYANYNYCDGRETSETTAMLQDEDVSSDGDEDAIVEVTPKLPKESSGIMALQILVPFLLAGFGTVSAGMVLDIVQHWEVFRKVTEVFILVPALLGLKGNLEMTLASRLSTAVNIGKMDSPIEKWNLIIGNLALKQVQATVVGFLAAVAAIILGWIPEGKYYLDHSILLCSSSVATAFIASLLQGIIMVGVIVGSKKTGINPDNVATPIAASFGDLITLAILAWISQGLYSCLETYYYISPLVGVFFLALTPIWIIIAAKHPATRTVLHSGWEPVITAMVISSIGGLILDTTVSDPNLVGIVVYTPVINGIGGNLVAIQASRISTYLHLHSIPGELPDEPKGCYYPFRTFFGPGVNNKSAQVLLLLVIPGHLIFLYTIHLMKSGHTSLTIIFIVVYLFAAVLQVFTLLWIADWMVHHFWRKGKDPDSFSIPYLTALGDLLGTALLALSFHFLWLIGDRDGDVGD
What is the function of this protein?
Acts as a plasma-membrane magnesium transporter.
What are the official names of this protein?
Solute carrier family 41 member 2.
What is the protein family that this protein belongs to?
Belongs to the SLC41A transporter family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ENOB_DICDI
Sequence: MSIESIKAREILDSRGNPTLEVEVWTSEGMFSAKVPSGASTGIHEAFELRDGDKSRYFGYGVLNAIVNVNNLISPTLKGMRVDNQKAIDDKMIELDGTKNKSKLGSNAIVGVSMAVARAAASIKGVPLYRYISQLAGNSNIRLPVPCFNVINGGKHAGNRLPFQEFMLVPIGAPKFKEALRYGSEVYHSLKEIIKERYGLDATNVGDEGGFAPNLTSPEEALTLLVDAINHSGYQDVIKIGIDSAASEFWNPKTSKYDMDFKNIGSSHLKSSLNSGEQLMSRYLEILKKYPIAFFEDPFGEDDWENHGKITAAIGNKIQIIGDDLLCTNPERIKKAISEKTVNSLLLKINQIGTLTETIEAAKLAKEAGWGCLVSHRSGETDDHFIADLVVGLGTGEIKSGAPCRFERLSKYNRLMKIEEELEKLHRSNGNSFEYAGEEFYHF
What are the official names of this protein?
Enolase B, 2-phospho-D-glycerate hydro-lyase B, 2-phosphoglycerate dehydratase B.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CUA2B_TENMO
Sequence: GLIGSPVATYAAAPVAVAKTVVADEYDPHPQYQYGYDVQDGLTGDSKSQIESRSGDVVQGSYSLVDPDGTRRTVEYTADPINGFNAVVHREPLVAKAVVAAHAPVVHAAPVAKIAHF
What is the function of this protein?
Component of the cuticle of the larva of Tenebrio molitor.
What are the official names of this protein?
Larval cuticle protein A2B, TM-LCP A2B, TM-A2B.
Protein: AMNLS_CANLF
Sequence: MGALGRALLWLQLCALARAAYKLWVPTTDFEAAANWSQNRTPCAGAVVQFPADKAVSVVVRASHGFSDMLLPRDGEFVLASGAGFGAADAGRDPDCGAGAPALFLDPDRFSWHDPRLWRSGDAARGLFSVDAERVPCRHDDVVFPPDASFRVGLGPGARPARVRSVQVLGQTFTRDEDLAAFLASRAGRLRFHGPGALRVGPGACADPSGCVCGDAEVQPWICAALLQPLGGRCPPAACPDALRPEGQCCDLCGAIVSLTHGPTFDIERYRARLLRAFLPQYPGLQAAVSKVRRRPGPHTEVQVVLAETGPQPGGAGRLARALLADVAEHGEALGVLSATARESGAPVGDGSAAGPLGSGSRAGLAGGVAAGLLLLLLALAAGLLLLRRAPRLRWTKRERLVATPVEAPLGFSNPVFDVAGSVGPVPRTPQPPPAQQAGSSSTSRSYFVNPLFAEAEA
What is the function of this protein?
Membrane-bound component of the endocytic receptor formed by AMN and CUBN.  Required for normal CUBN glycosylation and trafficking to the cell surface.  The complex formed by AMN and CUBN is required for efficient absorption of vitamin B12.  Required for normal CUBN-mediated protein transport in the kidney.
What are the official names of this protein?
Protein amnionless.
What are the subcellular locations of this protein?
Apical cell membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein. Endosome membrane. Membrane, coated pit. SUBCELLULAR LOCATION: [Soluble protein amnionless]: Secreted.
Protein: SECA_PSYIN
Sequence: MITGLITKIIGSRNDRYLKKLRKVADEINKLEPQMKALSDEELKAKTIEFKERLASGESLDKILVEAFAVVRNASERVFGMRQFDVQLIGGMVLNDNKIAEMRTGEGKTLTATLPAYLNALSGKGVHIITVNDYLAGRDAKWNAKLFEFLGLTVGINISGMSGDQKRAAYAADITYGTNNEFGFDYLRDNMAFEAQQRVMRSLHYAIIDEVDSILIDEARTPLIISGPTDGDATLYTELNTVIPMLTQQDKEDTEEYIGEGDFTVDEKNKQVLLTERGQEKVEVILQERGLLDENQSLYSAASISLLHHVNAALRAHTLFEKDVEYIVTEKGEVVIVDEHSGRTMPGRRWSEGLHQAVEAKEGVQIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFQSIYGLETIVIPTNQAMIRKDGGDLVYLTEQEKYQAIVDDIKPRLEKGQPILVGTVSIEHSELLSDLMDKAKIKHSVLNAKFHAKEADIIAQAGALGSVTIATNMAGRGTDIVLGGNLEARLDKLGDVSPKEIEAEKELWKEEHKKVLKAGGLYIVGTERHESRRIDNQLRGRSGRQGDPGESRFYLSMEDSLMRIFASEKVSNMMKKLGMEKGEAIEHPWVSRAIENAQRKVEGRNFDMRKSLLDFDDVSNEQRKVIYQQRNGVIDSEEITETIEQIWDDVFHNCVNEYVPPHSLTEQWDLEGLEQRLKADFLVDLPVRQWSIDDANLQEGSIREKVVEHAKASYLAKKEQVGPAIIGSFEKSVMLQTIDTLWKEHLAAMDHLRQGIHLRGYAQKDPKQEYKRESFELFLQMLENLKREVVVILSKVQVQSKEEADVIQEQRRQAEAKAQLEMKHAQVNKGEVVSDENTGDDTFVRNEKKVGRNEPCPCGSGKKYKQCHGKLD
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: LEUC_CERS5
Sequence: MTAPRTLYDKIWDDHVVHQAEDGTCLLYIDRHLVHEVTSPQAFEGLRMTGRKVRAPEKTIAVPDHNVPTTEGRDTKIDNEESRIQVEALDKNAKDFGINYYPVSDIRQGIVHIVGPEQGWTLPGMTVVCGDSHTATHGAFGALAHGIGTSEVEHVLATQTLIQKKSKNMKVEITGSLRPGVTAKDITLSVIGLTGTAGGTGYVIEYCGQAIRELSMEGRMTVCNMAIEGGARAGLIAPDEVTFAYVMGRPHAPKGAAWEAALSYWKTLYTDKGAHFDKVVTIRGEDIAPVVTWGTSPEDVLPITATVPSPEEFSGGKVEAARRSLDYMGLTPGMKLTDIKIDTVFIGSCTNGRIEDLRAAAAILKGKKIAPGMRAMVVPGSGLVRAQAEEEGLAQIFIDAGFEWRLAGCSMCLAMNPDQLSPGERCASTSNRNFEGRQGRNGRTHLVSPGMAAAAAITGHLTDVREMMAETV
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: Y1167_SYNY3
Sequence: MAPSISPVTQPLVSMAIAPTVVIRSALAKAGEHLQKLGSKGLVVTGSHSAELGEKSLQTLQKNYGLTLPLASYLPDCAESSLEQLRRRVHQEQPDFILGIGGGKALDTAKLLAHQTQLAIATVPTSAATCAGWTALANVYSETGAFRYDVALDRCPDLLIVDYELIQRAEPRLLVAGIGDAIAKWYEASVSSGQSSDTFTVAAVQQARILRDILFQKSAEALAQPGSETWREVVDASLLMAGVIGGLGGANCRTVAAHAVHNGLTQLPQAHHALHGEKVAYGILVQLRLEELVSGNQLAATARRQLLSFYDEIGLPKTLQDLGLGRISLEELRQTAEFTCLPNSDIHRLPFTVTPETLMAAMVSTLVEEQGTRQLFAQIQDNSGL
What are the official names of this protein?
Uncharacterized oxidoreductase slr1167.
What is the protein family that this protein belongs to?
Belongs to the iron-containing alcohol dehydrogenase family.
Protein: LEPA_CHLPM
Sequence: MAPSSPEVSRIRNFCIIAHIDHGKSTLADRLLEMTHTLDRTQMDSAQVLDDMDLERERGITIKSHAVQMKYCSVAGDDYTLNLIDTPGHVDFSYEVSRSLAACEGALLVVDATQGVEAQTIANLYLAIEAGLEIIPVINKIDLPSSDVEGVASQIIDLIGIEREEILQVSAKAGLGVPELMEAIIARVPSPADNGHLPLRALIFDSVFDAYRGAVVYLRIVDGVLRKGDRVRFFANNKVFLADEIGTMSMKRQPKQVLEAGDVGYLICSIKDVKDAKVGDTVTHADAPADKRLAGYKDVKPMVFSGLYPVNSNEFEDLRESLEKLSLNDASLVYTPETSVALGFGFRCGFLGLLHMEIIQERLEREYNMNIITTVPNVEYRVLMTNGETVIVDNPSKMPDTARITNVEEPYVSMQIITLADYIGNIMKLGMERRGEYRNTDYLDTKRVCMHFEFPLSEIVFDFHDRLKSISKGYASMDYEYIGYRESELVKLDVLLNGEPVDALSIIVHRSKAYDWGRKLCGKLKGIIPKQMYEVAIQAAIGSRIISRETISAMRKNVLAKCYGGDISRKRKLIEKQKEGKKRMKQVGRVEVPQEAFLAILNIDE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PXPA_ECODH
Sequence: MKIDLNADLGEGCASDAELLTLVSSANIACGFHAGDAQIMQACVREAIKNGVAIGAHPSFPDRENFGRSAMQLPPETVYAQTLYQIGALATIARAQGGVMRHVKPHGMLYNQAAKEAQLADAIARAVYACDPALILVGLAGSELIRAGKQYGLTTREEVFADRGYQADGSLVPRSQSGALIENEEQALAQTLEMVQHGRVKSITGEWATVAAQTVCLHGDGEHALAFARRLRSAFAEKGIVVAA
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: GON1_HAPBU
Sequence: MAAKILALWLLLAGTVFPQGCCQHWSYGLSPGGKRDLDNFSDTLGNMVEEFPRVEAPCSVFGCAEESPFAKMYRVKGLLASVAERENGHRTFKK
What is the function of this protein?
Stimulates the secretion of gonadotropins.  May be responsible for the regulation of the hypothalamic-pituitary-gonadal axis.
What are the official names of this protein?
Progonadoliberin-1, Progonadoliberin I.
What is the protein family that this protein belongs to?
Belongs to the GnRH family.
What are the subcellular locations of this protein?
Secreted.
Protein: TYSY_MYCPU
Sequence: MKQYLDFLKWVLEKGKHKENRTSVDTISAFGYQMRFDLSKGFPLVTTKKTNFSAIAHELLWFIKGDTNIKYLVDNKVNIWNQWPYESYKKSQDFQSESLKEFIQKIKDDNEFAQKHGNLGPVYGKQWRDFLGIDQLKKVIEQIKNNPNSRRLIVSSWNPSEIDTMLLPPCHTLFQFYVNDNKLSCHLYQRSADAFLGIPFNIASYALLTFLLAQETNLEVGDFVHSIGDAHIYVNHLEQVKTQLKRNPKELPKLIIKNKNIFEINFEDIELVDYEFDPIIKGEVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_XANAC
Sequence: MSTLLEQLIEAFRVLPGVGQKSAQRMAYHVLEREREGGRRLAAALGSAVEKVGHCVQCRDFTESEICTICASSSRDRQQLCVVESPADRLAIEHATGYRGLYFILQGRLSPLDGIGPRELGLDRLSERLAAGEVTEMIIATNATVEGEATAHYLAQLARQHAVRPSRLAQGMPLGGELEYVDRGTLSHAFGTRSEVL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: RL6_LEPBA
Sequence: MSRVGKSIIKLPAKVEVKADAEALTIKGPLGELKTPIYEGVSANVENGELVFTRKSEDQKTVALHGLVRSLAMNCVKGVTSGWEKNLEITGVGYRAQKRGKDLVMALGYSHEVVFPEPNGIKIEVADQLKIKVSGIDRQLVGQVAADIRSKRPPEPYKGKGIKYQNEYIRRKAGKTGKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.