PharMolix/UniProtQA huggingface dataset:
Protein: END8_SALA4
Sequence: MPEGPEIRRAADNLEAAIKGKPLTDVWFAFAQLKPYESQLTGQIVTRIETRGKALLTHFSNGLTLYSHNQLYGVWRVIDTGEIPKTTRILRVRLQTADKTILLYSASDIEMLTAEQLTTHPFLQRVGPDVLDARLTPEEVKARLLSPRFRNRQFSGLLLDQAFLAGLGNYLRVEILWQVGLTGQHKAKDLNEAQLNALSHALLDIPRLSYTTRGQADENKHHGALFRFKVFHRDGEACERCGGIIEKTTLSSRPFYWCPHCQK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine.  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Endonuclease 8, DNA glycosylase/AP lyase Nei, DNA-(apurinic or apyrimidinic site) lyase Nei, Endonuclease VIII.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: DNAJ_ACIBY
Sequence: MAKRDYYEVLGVSKTASDDEIKKAYRKLAMKYHPDRNPDNAEAEEKFKEASEAYEILSDSEKRSMYDRMGHNAFEGGFGGAGGGFGGFSAEDIFSQFGDIFGGAFGGGGRQQRQRRGSDLRYVMELTLEEAVKGVKKTITFTAPAPCDVCDGKGSKNPKDVETCKTCHGSGQVRMQQGFFSVQQTCGTCRGQGKIIKNPCHACHGSGVADRQQTLEVTIPAGVDNGDRVRLSGKGEAIRDGQAGDLYVEVVVREHEIFQRDGADLYMDVPVSIADAALGKEIEIPTLEGRVSLKIPEGTQTGKLFRLRGKGVRPVRSSMVGDLLCRIVVETPVNLTSRQRELLKELQASFDGEDSASSPKKKSFFDRLFD
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_PORGI
Sequence: MRKNIVAGNWKMNKTLQEGLALAKELDAALKGRTINCDVIIGTPFIHLASIAAAIDTTRIGVAAENCADKESGAYTGEVSAAMVASTGARYVIIGHSERRAYYHETSPILMEKVKLALSNGLTPIFCVGEVLEEREAGKHFEVVARQVEEALFTLDQTDFAKLILAYEPVWAIGTGKTATADQAQEMHAHIRKSIAAKYGKEVANGCSILYGGSCNAANAKELFSRADVDGGLIGGASLSVDKFLPIIEAF
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EGTC_MYCTU
Sequence: MCRHLGWLGAQVAVSSLVLDPPQGLRVQSYAPRRQKHGLMNADGWGVGFFDGAIPRRWRSPAPLWGDTSFHSVAPALRSHCILAAVRSATVGMPIEVSATPPFTDGHWLLAHNGVVDRAVLPAGPAAESVCDSAILAATIFAHGLDALGDTIVKVGAADPNARLNILAANGSRLIATTWGDTLSILRRADGVVLASEPYDDDSGWGDVPDRHLVEVTQKGVTLTALDRAKGPR
What is the function of this protein?
Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.  Ergothioneine is an antioxidant that protects mycobacteria from oxidative stress.
What are the official names of this protein?
Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase, Gamma-glutamyl hercynylcysteine S-oxide hydrolase.
Protein: YTJA_SALDC
Sequence: MFRWGIIFLVIALIAAALGFGGLAGTAAGAAKIVFVVGIVLFLVSLFMGRKRP
What are the official names of this protein?
UPF0391 membrane protein YtjA.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y658_METJA
Sequence: MLFNIFKKSNKKKLDEFLNENKDKVLTLKLDKPVDCLCDFTYNFIWQSKFNPETEIKENITFKTLVEHLKNGGVVYIKGNVGKRFCSSMGVDLKYFSGSGERIKVGTVIVDGDVDTRFGISMLSGTVYINEKNKIKEPMGNVIEVESDIKGYRKFISITEFVEERYKEEKLLKPNKFDKNKGILEINDKIKRDTVGARLNEDKTIVVNGDVDLSTGILMRKGKVIVNGNAGKNTGAVLNGGTVIINGNTNDFTGFEMRDGIIVVDGNAGKYLGAKKKEGVIYARDGKEVPPTKKYELNNDDIAFLKSLGYTGKFYKFI
What are the official names of this protein?
Uncharacterized protein MJ0658.
What is the protein family that this protein belongs to?
To M.thermoautotrophicum MTH238.
Protein: VF123_ASFWA
Sequence: MPSTGTLVIIFAIVLILCIMLLFFYKAAEARNPGVLPPPIPPPTPPPPKKKYDHNEYMEKTDLEPEVKKNHRKWANEAEHLISSSVKGLENLDETAFLANHKGHGFRTFDHAKSLFKEFLKKY
What are the official names of this protein?
Uncharacterized protein CP123L, pCP123L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus CP123L family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein. Virion.
Protein: DPNP4_ARATH
Sequence: MPYEKELAAAKKAVSLAARLSQEVQKSLLQSDVRSKSDKSPVTAADYGSQAVISHVLERELHPEPLYLVAEENAEDLHKNGAEEFLESITKLVNNALASDDSYANSSLSMDDVRKAIDHGRSQGGSSGRHWILDPVDGTRGFVKGEEYAVALALLVEGKVVLGVMACPKLENHKSSSSGCLFFATVGEGAYVQSLEGDSHPPQKVQVSNIENPEEATFVESSHKPIPIHSSIANKLGIKAPPLRIHSQVKYAALARGDAEIYLRFTLKGYREFIWNHAAGAIITTEAGGVVCDADGNPLDFSRGNHLEHKTGIVVSTKNLMPRLLKAIRESIEEEMLLSETQLKL
What is the function of this protein?
Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP.  Is also able to hydrolyze inositol 1,4-bisphosphate.
What are the official names of this protein?
Probable SAL4 phosphatase, 3'(2'),5'-bisphosphate nucleotidase 4, 3'(2'),5'-bisphosphonucleoside 3'(2')-phosphohydrolase 4, DPNPase 4, Inositol polyphosphate 1-phosphatase 4, IPPase 4, Inositol-1,4-bisphosphate 1-phosphatase 4.
What is the protein family that this protein belongs to?
Belongs to the inositol monophosphatase superfamily.
Protein: PYRF_ROSCS
Sequence: MNFFESLDTAAWRNQSRLCVGLDPEPARMPDCLPKDAEGIYTFCAAIMDATVDLVCAYKPNVAFFEAHGAAGWSALERLVKRRPGPPLILDAKRGDIGSTAEAYARSVFTTLGADAVTLSPYLGSDALEPFLRHADRGCFILCKTSNPGSGDLQDARLADGRPLYLAVAEMARDCWNMRGNVGLVVGATHPAALADIRRACPDMLILAPGVGAQGGDLEATVRAAAAGDDPRLIVNVSRTVLYADRGANFAAAARTAARQLRDAINAALRAV
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 2 subfamily.
Protein: NDH2_YARLI
Sequence: MLRLRPAVRAVSVARSVALTRSLHVSVAKFNKIEGTAPAGLPKEVKQTAGHQGHHQEIPKPDENHPRRKKFHFWRSLWRLTYLSAIASLGYIGYRIYVIRNPSDQLPADPSKKTLVVLGSGWGSVSFLKKLDTSNYNVIVVSPRNYFLFTPLLPSCPTGTIEHRSIMEPIRGIIRHKQAECQYLEADATKIDHEKRIVTIRSAVSENSKEEVIKEIPFDYLVVGVGAMSSTFGIPGVQENACFLKEIPDAQQIRRTLMDCIEKAQFEKDPEVRKRLLHTVVVGGGPTGVEFAAELQDFFEDDLRKWIPDIRDDFKVTLVEALPNVLPSFSKKLIDYTEKTFSDEKISILTKTMVKSVDENVIRAEQTKGDGTKETLEMPYGTLVWATGNTVRPVVRELMSKIPAQKGSRRGLLVNEYLVVEGTEGIWALGDCSATKYAPTAQVASQEGSYLANLLNGIAKTEDLNNEITNLEKQSEHTFDEQERKNIFAQLESKSRKLRRSRAMLPFEYSHQGSLAYIGSDRAVADLSFNFWGIMNWSSGGTMTYYFWRSAYVSMCFSMRNKILVCIDWMKVRVFGRDISRE
What is the function of this protein?
Alternative NADH-ubiquinone oxidoreductase which catalyzes the oxidation of mitochondrial NADH does not translocate protons across the inner mitochondrial membrane.
What are the official names of this protein?
External alternative NADH-ubiquinone oxidoreductase, mitochondrial, External alternative NADH dehydrogenase, NADH:ubiquinone reductase (non-electrogenic).
What is the protein family that this protein belongs to?
Belongs to the NADH dehydrogenase family.
Protein: MURD_LACH4
Sequence: MKDIKTYSNKNILVLGLGKSGFAVSELLLKLGAKLTLNDKADLDKNEKAQELKAKGVRVIGGHHPVDLLEKEHFDYLVKNPGIPYENPMVKKAEELNIPIITEPEIALSCSDAPYVCVTGSNGKTTTVMLTQRILDHHLQKSGHHAYAVGNIGVPISEVVPKATKDDILVVEISSFQLLGVTDIDPKVAAIVDIYNNVHLDYHKTFENYVNAKLNVTRTQNSDDYFIANYDQKDILAKEKEVTPAKMQTFSETDSSADYFIGDEYLESQNEKIMKIVDIKLPGIHNLQNSLVAIAISKVMGADNDDIAAVLSTFTGAKHRLQYVTTLDGRKVYNDSKSTNIEAATVAIPSFKEPEVLIAGGLDRGFLFDDLVPLFKKHVKSIVLYGETKYLLADAARKAGIKDIVIVNTLQEAVPRAYELSEPGDVILFSPACASWDQFRTFEDRGDYFVKFVKELKTK
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_ZYGBA
Sequence: MARTFFVGGNFKLNGTKSSIKEIVERLNNAKLDPKVEVVLCPPAPYLDYTVSLVKKSQVSVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRQYFREDDQLIAEKTAFALSQGVGVILCIGETLDQKKAGTTLQVVERQLQAVIDKVKDWSNVVIAYEPVWAIGTGLAATPEDAQEIHHSIREFLAKKLGEKTAQETRILYGGSANGKNAVTFKDKPDVDGFLVGGASLKPEFVDIINSRS
What are the official names of this protein?
Triosephosphate isomerase, TIM, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
Protein: YCEI_ECO57
Sequence: MKKSLLGLTFASLMFSAGSAVAADYKIDKEGQHAFVNFRIQHLGYSWLYGTFKDFDGTFTFDEKNPAADKVNVTINTTSVDTNHAERDKHLRSADFLNTAKYPQATFTSTSVKKDGDELDITGDLTLNGVTKPVTLEAKLIGQGDDPWGGKRAGFEAEGKIKLKDFNIKTDLGPASQEVDLIISVEGVQQK
What are the official names of this protein?
Protein YceI.
What is the protein family that this protein belongs to?
Belongs to the UPF0312 family. Type 1 subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: RS21_FLAJ1
Sequence: MLIIPIKDGENIDRALKRYKRKFDKTGTVRQLRARTAFIKPSVVKRAQIQKAAYIQTLKDSLES
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: LPXD_RIPO1
Sequence: MKFNEISEKLSPLVTNSSLTTHPDLNPDITAVAAVDEAVTGQLSYIEGGKFAAMVQKTAASALILPRDEALQAQATEKDIAWITTPEPRLLFAHAIKLFYQPFHPSPGIHPTAVIDSSVKLGKDIYIGPHVVIEQGVTIGDNACIHANVVIYPGVSIGDRTILHANCTIHERSQIGDNCVIHSGAAIGSEGFGFVPTPDGWFKMEQSGYVVLEDGVEIGCNSAVDRPAVGTTRVGRNTKIDNLVQVAHNCQISENCVFASQVGLAGGVKVGKRVILAGQVGVANQANIGDGVIASAQTGIPHDIAPGEIVSSSPAVPNKLYLKASAIYKRLPEMYQTLKRLQKKLEES
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: APCE_SYNY3
Sequence: MSVKASGGSSLARPQLYQTVPVSAISQAEQQDRFLEGSELNELTAYFQSGALRLEIAETLTQNADLIVSRAANRIFTGGSPLSYLEKPVERQPALVGASSDSRNGSVTYAESNGSGGLFGGLRSVFSSTGPIPPGFRPINIARYGPSNMQKSLRDMSWFLRYTTYAIVAGDPNIIVVNTRGLKEVIENACSIDATIVAIQEMRAASADYFRNNAQAKEIVLQYFDILLSEFKAPTPANKVRQGPSNDIQGLELPQSYFNAAAKRQKYAMKPGLSALEKNAVIKAAYRQIFERDITKAYSQSISYLESQVRNGDISMKEFVRRLAKSPLYRKQFFEPFINSRALELAFRHILGRGPSSREEVQKYFSIVSSGGLPALVDALVDSQEYADYFGEETVPYLRGLGVEAQECRNWGMQQDLFSYSAPFRKVPQFITTFAQYDRPLPDQHVYGSGNDPLEIQFGAIFPKETRNPSKRPAPFNKDTKRILIHRGPAVNNQVGNPSAVGEFPGSLGAKVFRLNGGLPGAKVGKNTGTSVKFGESSTQALIRAAYRQVFGRDLYEGQRLSVAEIQLENGDISVREFIKRLAKSELFLKLYWAPHYVCKAIEYMHRRLLGRPTYGRQEMNQYFDIASKQGFYAVVEAMIDSKEYSDAFGEDTVPYERYLTPGGLQMRSARVGSLREDIGQRVDKEVTPRFVELGQVSAIRTEPEIAYRSNQGVTRQRQQTKVFKLVSTYDKVAVKNAIRAAYRQVFERDLEPYIINSEFTALESKLSNNEINVKEFIEGLGTSELYMKEFYAPYPNTKVIEMGTKHFLGRAPLNQKEIQQYNQILASQGLKAFIGAMVNGMEYLQTFGEDTVPYRRFPTLPAANFPNTERLYNKLTKQDKELVVPSFTPVVKVGG
What is the function of this protein?
This protein is postulated to act both as terminal energy acceptor (by its phycobilin-like domains) and as a linker polypeptide (by its repeats and arms) that stabilizes the phycobilisome core architecture.  Has intrinsic bilin lyase activity (By similarity).
What are the official names of this protein?
Phycobiliprotein ApcE, Phycobilisome LCM core-membrane linker polypeptide, Phycobilisome core-membrane linker phycobiliprotein ApcE.
What is the protein family that this protein belongs to?
Belongs to the phycobilisome linker protein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=Anchors the phycobilisome perpendicularly to the cytoplasmic surface of the thylakoid membrane.
Protein: CITG_ECO27
Sequence: MSMPATSTKTTKLATSLIDEYALLGWRAMLTEVNLSPKPGLVDRINCGAHKDMALEDFHRSALAIQGWLPRFIEFGACSAEMAPEAVLNGLRPIGMACEGDMFRATAGVNTHKGSIFSLGLLCAAIGRLLQLNQPVTPTTVCSTAASFCRGLTDRELRTNNSRLTAGQRLYQQLGLTGARGEAEAGYPLVINHALPHYLTLLDQGLDPELALLDTLLLLMATNGDTNVASRGGEGGLRWLQREAQTLLQKGGIRTPADLDYLRQFDRECIERNLSPGGSADLLILTWFLAQI
What is the function of this protein?
Catalyzes the formation of 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A, the precursor of the prosthetic group of the holo-acyl carrier protein (gamma chain) of citrate lyase, from ATP and dephospho-CoA.
What are the official names of this protein?
2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase, 2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase.
What is the protein family that this protein belongs to?
Belongs to the CitG/MdcB family.
Protein: LYSY_THET2
Sequence: MDKKTLSIVGASGYAGGEFLRLALSHPYLEVKQVTSRRFAGEPVHFVHPNLRGRTNLKFIPPEKLEPADILVLALPHGVFAREFDRYSALAPILIDLSADFRLKDPELYRRYYGEHPRPDLLGCFVYAVPELYREALKGADWIAGAGCNATATLLGLYPLLKAGVLKPTPIFVTLLISTSAAGAEASPASHHPERAGSIRVYKPTGHRHTAEVVENLPGRPEVHLTAIATDRVRGILMTAQCFVQDGWSERDVWQAYREAYAGEPFIRLVKQKKGVHRYPDPRFVQGTNYADIGFELEEDTGRLVVMTAIDNLVKGTAGHALQALNVRMGWPETLGLDFPGLHP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of [LysW]-aminoadipate 6-phosphate to yield [LysW]-aminoadipate 6-semialdehyde.
What are the official names of this protein?
[LysW]-L-2-aminoadipate 6-phosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCA_ACISJ
Sequence: MQIYMVGGAVRDRLLGRPVNDHDWVVVGATPDDMVARGYLPVGRDFPVFLHPETREEYALARTERKSGRGYRGFVVQTSPDVTLEEDLSRRDLTINAIAASAAWTGAEDLFDPYGGARDLQARVLRHVTDSFREDPVRILRVARFAARFTDFTVAPETMQLMREMVHDGEADHLVPERVWQELARGLMEPQPSRMFDVLRDCGALAVVLPEVERLWGVPQRPEYHPEVDTGVHLMMVLDMAAHLQAPLTVRFACLTHDLGKGTTPHDVLPRHIGHEQRSARLLKAVCERLRVPVECRELADVVAREHGNIHRSGDLGAAALVRLLERCDAIRKPARLDEILLACECDARGRLGFADRPYPQRARINAALAAVQSVTTSSVAAHAAQLGLSGPKVGEMIHAARVQAVADWLHATAQPAPEPQGNAG
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: CO2A1_CHICK
Sequence: LQGLPGKDGETGAAGPLDPGPVGERGEQGAPGPSGFQGLPGPPGPPGESGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGATGPAGPNGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGARGLTGPIGPPGPAGPNGEKGESGPPGPSGAAGARGAPGERGEPGAPGPAGFAGPPGADGQPGAKGEQGEPGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGPNGNPGPPGPPGSAGKDGPKGVRGDAGPPGRAGDPGLQGPAGPPGEKGEPGEDGPAGPDGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGSAGDRGPPGPVGPPGLTGPAGEPGREGNPGADGPPGRDGAAGVKGDRGETGPVGAPGAPGAPGAPGPVGPTGKQGDRGETGAQGPMGPSGPAGARGMPGPQGPRGDKGETGEAGERGLKGHRGFTGLQGLPGPPGPSGDQGAAGPAGPSGPRGPPGPVGPSGKDGSNGMPGPIGPPGPRGRSGEPGPAGPPGNPGPPGPPGPPGTGIDMSAFAGLGQTEKGPDPIRYMRADEAAGGLRQHDVEVDATLKSLNNQIESIRSPEGSKKNPARTCRDIKLCHPEWKSGDYWIDPNQGCTLDAIKVFCNMETGETCVYPTPSSIPRKNWWTSKTKDKKHVWFAETINGGFHFSYGDENLSPNTASIQMTFLRLLSTEGSQNVTYHCKNSIAYMDEETGNLKKAILIQGSNDVEIRAEGNSRFTYSVLEDGCTKHTGKWGKTVIEYRSQKTSRLPIVDIAPMDIGGADQEFGVDIGPVCFL
What is the function of this protein?
Type II collagen is specific for cartilaginous tissues.  It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces.
What are the official names of this protein?
Collagen alpha-1(II) chain, Alpha-1 type II collagen.
What is the protein family that this protein belongs to?
Belongs to the fibrillar collagen family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: Y1811_STAAS
Sequence: MNDQWYKHLIGARTIKTGIAIFLTAVFCMALDLTPIYAILTAVVTIEPTAKASLIKGYRRLPATVIGAGFAVLFTYLFGDQSPFTYALSATFTILFCTKLKLQVGTNVAVLTSLAMIPGIHDAYIFNFLSRTLTAIIGLVTSGLINFMVFPPKYYGQVEEKLSKTDALMYKLFYNRCQELILSRLQSDKSEKAYKNIFNLNNQVETLISYQRDELSYHKKKECDWKLLNQLTKRAYTNRLFITHLSNIIYLPKNTRVNFSGDEKMALLKISSSIKDIFYDGSFKREDDSVETLRSTIKALEISGENQIKSHILYEVLMIYRLLDSRYA
What are the official names of this protein?
UPF0421 protein SAS1811.
What is the protein family that this protein belongs to?
Belongs to the UPF0421 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PBPA_NEIG1
Sequence: MIKKILTTCFGLFFGFCVFGVGLVAIAILVTYPKLPSLDSLQHYQPKMPLTIYSADGEVIGMYGEQRREFTKIGDFPEVLRNAVIAAEDKRFYRHWGVDVWGVARAAVGNVVSGSVQSGASTITQQVAKNFYLSSEKTFTRKFNEVLLAYKIEQSLSKDKILELYFNQIYLGQRAYGFASAAQIYFNKNVRDLTLAEAAMLAGLPKAPSAYNPIVNPERAKLRQKYILNNMLEEKMITVQQRDQALNEELHYERFVRKIDQSALYVAEMVRRELYEKYGEDAYTQGFKVYTTVRTDHQKAATEALRKALRNFDRGSSYRGAENYIDLSKSEDVEETVSQYLSGLYTVDKMVPAVVLDVTKKKNVVIQLPGGRRVALDRRALGFAARAVDNEKMGEDRIRRGAVIRVKNNGGRWAVVQEPLLQGALVSLDAKTGAVRALVGGYDFHSKTFNRAVQAMRQPGSTFKPFVYSAALSKGMTASTVVNDAPISLPGKGPNGSVWTPKNSDGRYSGYITLRQALTASKNMVSIRILMSIGVGYAQQYIRRFGFRPSELPASLSMALGTGETTPLKVAEAYSVFANGGYRVSSHVIDKIYDRDGRLRAQMQPLVAGQNAPQAIDPRNAYIMYKIMQDVVRVGTARGAAALGRTDIAGKTGTTNDNKDAWFVGFNPDVVTAVYIGFDKPKSMGRAGYGGTIAVPVWVDYMRFALKGKQGKGMKMPEGVVSSNGEYYMKERMVTDPGLMLDNSGIAPQPSRRAKEDDEAAVENEQQGRSDETRQDVQETPVLPSNTDSKQQQLDSLF
What is the function of this protein?
Cell wall formation.  Synthesis of cross-linked peptidoglycan from the lipid intermediates.  The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).  Essential for cell wall synthesis.
What are the official names of this protein?
Penicillin-binding protein 1A, PBP-1a, PBP1a.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transpeptidase family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: IRC4_YEAST
Sequence: MREYTSKKELKEEIEKKYEKYDAEFETISESQKDEKVETVDRTPSENLSYQLGWVNLLLEWEAKEIAGYNVETPAPGYKWNNLGGLYQSFYKKYGIYSIKEQRAKLREAVNEVYKWISTLSDDELFQAGNRKWATTKAMWPVYKWIHINTVAPFTNFRGKIRKWKRLVPEEQRIKRRKI
What are the official names of this protein?
Uncharacterized protein IRC4, Increased recombination centers protein 4.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: YGIB_SHIDS
Sequence: MKRTKSIRHASFRKNWSARHLTPVALAVATVFMLAGCEKSDETVSLYQNADDCSAANPGKSAECTTAYNNALKEAERTAPKYATREDCVAEFGEGLCQQAPAKAGMAPENQAQAQQSSGSFWMPLMAGYMMGRLMGGGAGFAQQPLFSSKNPASPAYGKYTDATGKNYGAAQPGRTMTVPKTAMAPKPATTTTVTRGGFGESVAKQSTMQRSATGTSSRSMGG
What are the official names of this protein?
UPF0441 protein YgiB.
What is the protein family that this protein belongs to?
Belongs to the UPF0441 family.
Protein: POLS_IPNVJ
Sequence: MSTSKATATYLRSIMLPENGPASIPDDITERHILKQETSSYNLEVSESGSGLLVCFPGAPGSRVGAHYRWNLNQTALEFDQWLETSQDLKKAFNYGRLISRKYDIQSSTLPAGLYALNGTLNAATFEGSLSEVESLTYNSLMSLTTNPQDKVNNQLVTKGITVLNLPTGFDKPYVRLEDETPQGPQSMNGARMRCTAAIAPRRYEIDLPSERLPTVAATGTPTTIYEGNADIVNSTAVTGDITFQLEAEPVNETRFDFILQFLGLDNDVPVVTVTSSTLVTADNYRGASAKFTQSIPTEMITKPITRVKLAYQLNQQTAIANAATLGAKGPASVSFSSGNGNVPGVLRPITLVAYEKMTPQSILTVAGVSNYELIPNPDLLKNMVTKYGKYDPEGLNYAKMILSHREELDIRTVWRTEEYKERTRAFKEITDFTSDLPTSKAWGWRDLVRGIRKVAAPVLSTLFPMAAPLIGAADQFIGDLTKTNSAGGRYLSHAAGGRYHDVMDSWASGSEAGSYSKHLKTRLESNNYEEVELPKPTKGVIFPVVHTVESAPGEAFGSLVVVIPEAYPELLDPNQQVLSYFKNDTGCVWGIGEDIPFEGDDMCYTALPLKEIKRNGNIVVEKIFAGPAMGPSSQLALSLLVNDIDEGIPRMVFTGEIADDEETVIPICGVDIKAIAAHEHGLPLIGCQPGVDEMVANTSLASHLIQGGALPVQKAQGACRRIKYLGQLMRTTASGMDAELQGLLQATMARAKEVKDAEVFKLLKLMSWTRKNDLTDHMYEWSKEDPDAIKFGRLVSTPPKHQEKPKGPDQHTAQEAKATRISLDAVKAGADFASPEWIAENNYRGPSPGQFKYYMITGRVPNPGEEYEDYVRKPITRPTDMDKIRRLANSVYGLPHQEPAPDDFYQAVVEVFAENGGRGPDQDQMQDLRDLARQMKRRPRPAETRRQTKTPPRAATSSGSRFTPSGDDGEV
What is the function of this protein?
Structural peptide 3 is a small peptide derived from pre-VP2 C-terminus.  It is not essential for virus viability, but viral growth is affected when this protein is absent (By similarity).
What are the official names of this protein?
Structural polyprotein, PP.
What are the subcellular locations of this protein?
[Capsid protein VP2]: Virion. Host cytoplasm. SUBCELLULAR LOCATION: [Capsid protein VP3]: Virion. Host cytoplasm. SUBCELLULAR LOCATION: [Structural peptide 1]: Virion. Host cytoplasm. SUBCELLULAR LOCATION: [Structural peptide 2]: Virion. Host cytoplasm. SUBCELLULAR LOCATION: [Structural peptide 3]: Virion. Host cytoplasm.
Protein: SGT1_SOLTU
Sequence: MVATCNNGEILHVLFLPFLSAGHFIPLVNAARLFASRGVKATILTTPHNALLFRSTIDDDVRISGFPISIVTIKFPSAEVGLPEGIESFNSATSPEMPHKIFYALSLLQKPMEDKIRELRPDCIFSDMYFPWTVDIADELHIPRILYNLSAYMCYSIMHNLKVYRPHKQPNLDESQSFVVPGLPDEIKFKLSQLTDDLRKSDDQKTVFDELLEQVEDSEERSYGIVHDTFYELEPAYVDYYQKLKKPKCWHFGPLSHFASKIRSKELISEHNNNEIVIDWLNAQKPKSVLYVSFGSMARFPESQLNEIAQALDASNVPFIFVLRPNEETASWLPVGNLEDKTKKGLYIKGWVPQLTIMEHSATGGFMTHCGTNSVLEAITFGVPMITWPLYADQFYNEKVVEVRGLGIKIGIDVWNEGIEITGPVIESAKIREAIERLMISNGSEEIINIRDRVMAMSKMAQNATNEGGSSWNNLTALIQHIKNYNLN
What is the function of this protein?
Glucosyltransferase involved in the glucosylation of the steroidal alkaloid aglycons solanidine, solasodine and tomatidine to produce their corresponding glycoalkaloids.
What are the official names of this protein?
Solanidine UDP-glucose glucosyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: RBFA_NOCFA
Sequence: MVDQARARRLAKRISEIVATAIEYEVKDPRLRFVTITDAKVTGDLREATVYYTVMGETIDAEPDYDAAAAGLAKAKGVLRSKVGAGTGVKFTPSLAFVLDKVPDAAREMEELLARARAADAEVARVAAEARHAGEPDPYKTDRDDAE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIM_METS3
Sequence: MTNKEKLLQKIPELLNEVKSKNPLTHCITNFVTVNDCANAVLAIGASPIMSEDIEEVAEVVSIADALVINIGKLSHEQVEAMKISSAQANKINTPVILDPVGVGISQLRNKVTLEIIENYKLAAIRGNITEIKTIAKLTGIISESNTAKGVDVSESDIITQDNLNENADVISKLAAKLDTVILASGPIDILSDGETTIAIDNGDEMMPYITGSGCMLSSIVGSCIGATNPLEGTMVAALLMTIAGEKARSKVDSENAGTGSFRAYLIDYLYKLDGQTLINKSNIEIL
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.