PharMolix/UniProtQA huggingface dataset:
Protein: TSAD_PSEPW
Sequence: MLVLGLETSCDETGVALYDSERGLLADALFSQIDLHRVFGGVVPELASRDHVKRMLPLIRQVLDEAGCVATEIDAIAYTAGPGLVGALLVGASCAQALAFAWDIPAIGVHHMEGHLLAPMLEENPPQFPFVALLVSGGHTQLVRVDGIGQYELLGESLDDAAGEAFDKTAKLIGLNYPGGPEIARLAERGVPGRFVFPRPMTDRPGLAFSFSGLKTFALNTWQQCRDAGDDNEQTRCDVSLAFQQAVVETLTIKCKRALKQTGLKRLVIAGGVSANKALRASLEDMLGSIKGNVYYARPQFCTDNGAMIAYAGCQRLLAGQQQDLAISVQARWPMEQLPPL
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_CUPNH
Sequence: MAVADINKSEVIKQFARGANDTGSPEVQVALLTTRINELTPHFKANMKDHHSRRGLLRMVSRRRRLLDYLKSNDADRYRALIEKLGLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: NSP2_ROTHD
Sequence: MAELACFCYPHLENDSYKFIPFNNLAIKCMLTAKVDKKDQDKFYNSIIYGIAPPPQFKKRYNTNDNSRGMNYETSMFNKVAALICEALNSTKVTQSDIASVLSRVVSVRHLENLVLRRENHQDVLFHSKELLLKSVLIAIGHSKEIETTATAEGGEIVFQNTAFTMWRLTYLEHKLMPILDPNFIEYKITVNEGKPISESHIKELIAELRWQYNKFAVITHGKGHYRVVKYSSVANHADRVYATYKSNNKNGNMLEFNLLDQRIIWQNWYAFTSSMKQGNTLDTCKKLLFQKIKRESNPFKGLSTDRKMDEVSQIGI
What is the function of this protein?
Participates in replication and packaging of the viral genome.  Plays a crucial role, together with NSP5, in the formation of virus factories (viroplasms) which are large inclusions in the host cytoplasm where replication intermediates are assembled and viral RNA replication takes place.  Displays ssRNA binding, NTPase, RNA triphosphatase (RTPase) and ATP-independent helix-unwinding activities.  The unwinding activity may prepare and organize plus-strand RNAs for packaging and replication by removing interfering secondary structures.  The RTPase activity plays a role in the removal of the gamma-phosphate from the rotavirus RNA minus strands of dsRNA genome segments.
What are the official names of this protein?
Non-structural protein 2, NSP2, NCVP3, Non-structural RNA-binding protein 35, NS35.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP2 family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Found in spherical cytoplasmic structures, called viral factories, that appear early after infection and are the site of viral replication and packaging.
Protein: AGUA_ASPTN
Sequence: MLRLPLVLVWSLWASLTVAENGLNGWLRYAPIPCDGRCHKALPSRIVALNSTQGSPLETAIEELQTGVRGMTGKRLSVAKENNCNLHATALIATVEEYRRTCRNSSDIPDLDVDGFWLRTEGNNVQILGQSERGALYGAFEYLSMLAQGDFSSVDYSTSPHAPVRWVNQWDNMDGSIERGYAGPSIFFAQGQIVPDLSRAKQYARLLASVRINGIIVNNVNANATLLTPQNMDGLARIANVFRPYGIRIGIALNFASPDTLGGLGTYDPLDPSVISWWGNITDSLYERIPDMAGYLVKASSEGQPGPDTYNRTLADGANLFARALKPHGGVMMFRAFVYDHHINESIWTNDRANAQVDFFKKLDGQFEDNVIVQIKYGPIDFQVREPVSPLFANLYHTNTAIELQVTQEYLGQQCHLVYLPPLWKTITDFDLRVDHSPSVVRDIISGERFNRPLGGWAAVVNVGTNDTWLGSHLSMSNLYAYGRMAWSPTDDSVEILQDWIRLTFGRDQHVLDTITDMSMASWPAYENYTGNLGIQTLTDILYTHYGPNPASQDGNGWGQWTRADHDSIGMDRTVKNGTGNAGQYPAEIAEIYEDIDKTPDDLLLWFHHVPYTHRLDSGKTVIQHFYDAHYAGAETAQGFVPQWESLRGRIDPERYDAMRTRLVYQAGHSIVWRDAINNFYWNLSGIADTNGRVGHHPWRVEAESMQLQGYQPYAVSPFETASNYTAVVTTSNSTTGTASTTLDFPSGTYDVGVNYFDMYGGKSRWSLYLNDKVVGKWEGNSEDVLGHTPSIYLDGHSAIRITFNGVKVRKGDRLKIVGVPDGVEPAPLDYVVFLPQGVID
What is the function of this protein?
Alpha-glucuronidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.  Releases 4-O-methylglucuronic acid from xylan (By similarity).
What are the official names of this protein?
Probable alpha-glucuronidase A, Alpha-glucosiduronase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 67 family.
What are the subcellular locations of this protein?
Secreted.
Protein: HYDRA_RHIML
Sequence: MHIHLINPNSTASMTAQALESALLVKHAHTHVSASNPTDTPASIEGGADEAMSVPGMLAEIRQGEAQGVDAYVIACFDDPGLHAAREVAKGPVIGICQAAVQVAMTISRRFSVITTLPRSVPIIEDLVSDYGAERHCRKVRAIDLPVLALEEDPQRAERLLLKEIEIAKAEDGAEAIVLGCAGMSSLCDRLQKATGVPVIDGVTAAVKMAEALLGAGYATSKVNTYAYPRIKAAAGHKVCA
What is the function of this protein?
May be involved in the asymmetric conversion of racemic 5-substituted hydantoins to the corresponding L-amino acids.  Catalyzes the racemization via enolization of D- and L-5-monosubstituted hydantoins.  It shows a slight preference for hydantoins with short rather than long aliphatic side chains or those with aromatic rings.
What are the official names of this protein?
Hydantoin racemase.
What is the protein family that this protein belongs to?
Belongs to the HyuE racemase family.
Protein: CDPAS_THEPD
Sequence: MRISVYACFLGLYFLVFSLIVYVILGAEFLVSVLQPGNVARSMLWVLPAYVANASPVVFSRLVRKRWRLHPMDFGLTFVDGQRLLGDNKTFEGFLGGMLSGVLVGILLAYARFVDGVSAFLLPLGALLGDLGGAFVKRRLRIKPGEPAILLDQLDFVAGALILQGLFSKLPAAEVVVAVVLLTPIVHLLTNMAAFVLGLKDVPW
What is the function of this protein?
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP.  This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
CDP-archaeol synthase, CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-archaeol synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HIS6_METS3
Sequence: MLTKRIIPCLDCDLQVPEGRVVKGVEFKEIKYAGNPVDLATRYYEMGADEIVILDITASYERRATMADVIDRLTENVFIPICVGGGIRKVEDYTKMLKAGADKCSTNTAAIKNPELLTEASKVVGSQAVVVGIDAKRRYVDNPSDAPDKNVVETDEGYCWFDCSIYGGREFTGMDAIEWAVKCQELGAGEILLTSMDGDGTKEGYDIALNKAINDAIDIPVIASGGGGNPAHILDVFQKTDVSAALAASIFHFNQYSINDVKQYLKENNVPVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPS_YERPS
Sequence: MSPVKEDRANLSPRSPRHVAIIMDGNGRWAKNKGKLRVFGHKAGVKSVRRAVSFAAKHNLDALTLYAFSSENWNRPDQEVTALMELFVRALDSEVKSLHKHNVRLSIIGDISRFSGRLQERIRRSEKLTANNDGLKLNIAANYGGRWDIIQGVRHLAEQVQKGELQPTDISEESLNSYICLHEQSQVDLVIRTGGEHRISNFLLWQIAYAELYFTDVLWPDFDENVFEGALNAFAQRERRFGGTTPIDATAS
What is the function of this protein?
Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP).  UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
What are the official names of this protein?
Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific), Ditrans,polycis-undecaprenylcistransferase, Undecaprenyl diphosphate synthase, UDS, Undecaprenyl pyrophosphate synthase, UPP synthase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: AMZA_ARCFU
Sequence: MKIYIQPLSVNSHTVEVLANSLPKIFNAEVFVLPASDVSLKCYNASRRQYNSTCILRMLPPIKVTLGVTGKDIYAKGMNFVFGEAELGGARAVLSVFRLTTADSELYRERVVKEAVHEIGHVLGLKHCSNNCVMRFSNSVQDVDRKPVSFCRECASKIRY
What is the function of this protein?
Probable zinc metalloprotease whose natural substrate is unknown.
What are the official names of this protein?
Archaemetzincin.
What is the protein family that this protein belongs to?
Belongs to the peptidase M54 family.
Protein: LGT_CROS8
Sequence: MNSGYLHFPDFDPVIFSLGPVSLHWYGLMYLVGFVFAMWLAVRRANRPGSGWTKNEVENLLYAGFLGVFLGGRIGYVLFYNLPLFLENPLYLFRVWDGGMSFHGGLIGVICVMIWFAKRTKRNFFQVSDFIAPLIPFGLGAGRLGNFINGELWGRVDPGFPYAMLFPGSRSEDIGLLASHPEWQSLFNTYGVLPRHPSQLYELFLEGIVLFIILNLFIRKPRPMGAVSGLFLIGYGAFRIIVEFFRQPDAQFTGEWVQYISMGQILSIPMIVAGAAMMIWAYRRRPQQQLS
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL22_XANC5
Sequence: MEAKAILRTARISPQKARLVADQVRGLSAERAVNLLKFSDKKAAHLIKKVVESAIANAENNQGADVDELKVKTIMVDEGPSLKRFMARAKGRGTRILKRTSHITVVVGAAK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: STOX2_HUMAN
Sequence: MKKTRSTTLRRAWPSSDFSDRASDRMRSRSEKDYRLHKRFPAAFAPQASRGYMTSGDVSPISMSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFPGVPTPSQEILRHTLNTLVRERKIYPTPDGYFIVTPQTYFITPSLIRTNSKWYHLDERIPDRSQCTSPQPGTITPSASGCVRERTLPRNHCDSCHCCREDVHSTHAPTLQRKSAKDCKDPYCPPSLCQVPPTEKSKSTVNFSYKTETLSKPKDSEKQSKKFGLKLFRLSFKKDKTKQLANFSAQFPPEEWPLRDEDTPATIPREVEMEIIRRINPDLTVENVMRHTALMKKLEEEKAQRSKAGSSAHHSGRSKKSRTHRKSHGKSRSHSKTRVSKGDPSDGSHLDIPAEREYDFCDPLTRVPREGCFIIEHKGDNFIMHSNTNVLESHFPMTPEWDVSGELAKRRTEMPFPEPSRGSSHSKVHRSHSHTQDRRSRNERSNKAKERSRSMDNSKGPLGASSLGTPEDLAEGCSQDDQTPSQSYIDDSTLRPAQTVSLQRAHISSTSYKEVCIPEIVSGSKEPSSACSLLEPGKPPESLPSYGELNSCPTKTATDDYFQCNTSSETVLTAPSPLGKNKEDHDTLTLAEGVKKLSPSDRQVPHSSREPVGHKEESPKGPGGGPAASGGVAEGIANGRLVQHHGAEPSSLDKRKEIFSKDTLFKPLHSTLSVNSYHKSSLSLLKSHPKTPADTLPGRCEKLEPSLGTSAAQAMPASQRQQESGGNQEASFDYYNVSDDDDSEEGANKNTEEEKNREDVGTMQWLLEREKERDLQRKFEKNLTLLAPKETDSSSNQRATHSARLDSMDSSSITVDSGFNSPRTRESLASNTSSIVESNRRQNPALSPAHGGAGPAFNFRASAEPPTNEAEKLQKPSNCLQASVTSV
What are the official names of this protein?
Storkhead-box protein 2.
Protein: HIS6_CARHZ
Sequence: MLTVRIIPCLDVNKGRVVKGVNFLNLVDAGDPVELAAFYDREGADEVVFLDITASFEGRQTMVEVAKRTATTLSIPFTIGGGIRNIDDIRALLASGADKVSINSAAVKNPELVREAALKFGSQCIVVAIDAKRKKDGGFEVYIHGGRTPTGIDAVEWAKEVERLGAGEILLTSMDRDGTKDGYDLELTREIADAVKIPVIASGGVGELSHFYEGVVLGHASALLAASVFHFGKFTIKEVKRYLKERGIPVRLGDTENGT
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_CERSK
Sequence: MANVVVVGAQWGDEGKGKIVDWLSERADVIARFQGGHNAGHTLVIDGKVYKLSLLPSGIVRPGKLSVIGNGVVLDPWHLVQEIAKLRADGVEISPESLMIAENAVLILPLHGELDRARESQNSVAKIGTTGRGIGPAYEDKVGRRAIRVADLADEATLALRVDRLMVHHDALRRGLGIEPVDREALLAQLREIAPQVLPYAKPVWKVMNEMRKAGKRILFEGAQGALLDIDFGTYPYVTSSNVIAGQAATGTGIGPGAIGFVLGIVKAYTTRVGEGPFPAELQDADGERLGERGREFGTVTGRKRRCGWFDAVLVRQTCATSGVSGIALTKLDVLDGFETLKICVGYELDGERLDHLPIAADQQARCTPIFEELEGWSESTAGARSWADLPGAAVKYVRRIEELIQCPVALLSTSPERDDTILVTDPFED
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASSY_CAUSK
Sequence: MANKPVKKVVLAYSGGLDTSIILKWLQTEYGAEVVTFTADLGQGEEIEPARAKALAAGVKPENIFIEDVREEFVRDYVFPMFRANTVYEGQYLLGTSIARPLIAKKQIEIARKVGADAVSHGATGKGNDQVRFELGYYALEPDIHVIAPWREWDFKSREALLDFAEKHQIQIAKDKRGEAPFSVDANLLHSSSEGKVLEDPAVEAPEFVHMRTIAPEDAPDKPHIFTLDFERGDAVAIDGVAMSPATILTKLNELGHDNGVGRLDLVENRFVGMKSRGVYETPGGTILLAAHRGIESITLDRGSMHLKDELMPKYASLVYNGFWFSPEREMLQAAIDYSQAKVAGQVRVKLYKGNVSIIGRTSPYSLYDQDLVTFEEGKVAYDHRDAGGFIKLNALRLRVLAKRDKR
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSB_RHIEC
Sequence: MGDSNFDDVLVLIPARMASTRLPGKPLADICGLPMIVQVAMRAKEAEIGRVVVAVDDPQVFDTVAAAGFEVVMTSKDHQSGSDRIFEALKKIDPDGKAKFIVNVQGDLPTIEPETVRAALRPLENEAVDIGTLTIEIDNEEDKTAPHIVKVIGSPISDNRLRGLYFTRATAPYGKGPLYHHIGLYAYRRAALERFVSLGPSTLERRESLEQLRALEAGMRIDAEIVDTVPLGVDTPADLEKARRILSARQN
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VG40_BPPH8
Sequence: MENTGLHDVNFSLRYDGLDAEKHEIELSSLGESLKGFSKILATAGTFALTQKYSRRPSTQEVKIYATEARANCFSLDTIMNFISQSQLFSGSAGAILGALVPYIFAKNSQKKEEMKYLKEALEKAIEALGNKDKDTISGLISVIDKMASELRPSVRQAVSPIGTTCNKISVTPGNGFKPAVIDEQDKAVIDQLDDDEVLGLREYRILPY
What are the official names of this protein?
Protein 40A.
Protein: FETP_BAUCH
Sequence: MSKNIYCVFLRKQAEGQDFQSYPGELGKHIFNNISKEAWAKWQQKQTMLINENKLNLISNTDRNFLEKEMIKFLFKS
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: RNH2_AGRFC
Sequence: MKRTATPDSPALFDLVDTGPDFAFELEAKKKGFWPVAGTDEAGRGPLAGPVVAAAVILDPDNIPKGMDDSKKLTRQKRESLFVQIMETSIVSVASSGPGLIDSVNILRASLDAMRRAVLGLEIPPALVLADGRDRPPGIPCEAKAVIKGDSRSLSIAAASIIAKVTRDRMMERAGVVHTSYGFEGHAGYGTPAHLRAIESHGPCALHRMSFRPLKRD
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIF3C_ASPFU
Sequence: MSSRFFYGGGSDSDSSSSDEEELYSDREEEEKSEEEESSEEEDETSEEEESDEETGARKFLKDVASDSEEEEEEEKVTVVKSAKDKRLDELENTIKLIENAKKINDWAVISTEFDKLNRQVAKITQSGPTPKIYIKAVADLEDFVNETVAKQKSGDKKLNASQAKGFNAAKQRIKKNNKDYGNLIDKYRKDKEDFMESDDEEAIPVIAAPRITKLERIEAPAAAIDDDGFATVGRGGKTLQYTPESILKHLRVIVESRGKKNTDRMEQIRTMEKLLEVAQTPYQRIRVYLTLISTRFDLTSTSSANYMAVDQWKSAEQDFSSLLSVLENNRDHVVFEGAEEWEDDEKQPTIAPGETLYIPGSIVSFAERLDDELTRSLQHIDPHTAEYIERLSDEKLLYTDLVRAQAYVEGLNEVEKTDPRQDSVNRVVMRRLEHVYFKPSQVITILEDATWKSLPSELDSSITPRASSGNVENLVLSLCNYLFKYSDGIIRARAMLCQIYFLALHDQYYRSRDLMLMSHLTENISNFDVSTQILFNRTLVQIGLCAFRSGLIYEAQNTLSEVCGSGRQKELLAQGIIMQRYSTVSPEQERLERQRQLPFHMHINLELLECIYLTSSMFLEVPLMAQTSSSPEMKRRVISKTFRRMLDYNERQVFTGPPENTRDGVIMSAKFLAAGDWKKAAEMLNSIKIWDLMPQPDKIKEMLSQQIQEEGLRTYLFTYAPFYDSLSIATLSNMFELSEKKISAIISRMISHEELAAALDQVNNAIVFRKGVELSRLQSQIVTLADKSMNLLEANEKTLEQRTQGMANAFQRDQGAGARGGRGSGRGGQARGGPRFPGGQQGRRPGGQQFGGGALGGAIKA
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit C, eIF3c, Eukaryotic translation initiation factor 3 93 kDa subunit homolog, eIF3 p93, Translation initiation factor eIF3, p93 subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALG2_YEAST
Sequence: MIEKDKRTIAFIHPDLGIGGAERLVVDAALGLQQQGHSVIIYTSHCDKSHCFEEVKNGQLKVEVYGDFLPTNFLGRFFIVFATIRQLYLVIQLILQKKVNAYQLIIIDQLSTCIPLLHIFSSATLMFYCHFPDQLLAQRAGLLKKIYRLPFDLIEQFSVSAADTVVVNSNFTKNTFHQTFKYLSNDPDVIYPCVDLSTIEIEDIDKKFFKTVFNEGDRFYLSINRFEKKKDVALAIKAFALSEDQINDNVKLVICGGYDERVAENVEYLKELQSLADEYELSHTTIYYQEIKRVSDLESFKTNNSKIIFLTSISSSLKELLLERTEMLLYTPAYEHFGIVPLEAMKLGKPVLAVNNGGPLETIKSYVAGENESSATGWLKPAVPIQWATAIDESRKILQNGSVNFERNGPLRVKKYFSREAMTQSFEENVEKVIWKEKKYYPWEIFGISFSNFILHMAFIKILPNNPWPFLFMATFMVLYFKNYLWGIYWAFVFALSYPYEEI
What is the function of this protein?
Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.
What are the official names of this protein?
Alpha-1,3/1,6-mannosyltransferase ALG2, Asparagine-linked glycosylation protein 2, GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase, GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase, GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PCRB_LISMO
Sequence: MKHLFKLDPAKNLPTNDVTKLIHSGTDGFIIGGTDNVQIEAVQNLYELLVETDLPIFLEISNESMILPEADHFLIPVVLNTENSKWTHGLHKELIKEMGEFIPWKRVTSEGYVILNKDAKVAHLTEAKTDLTDEDIVAYARLAENIFHLPIFYVEYSGMYGDPEVVRKASAALSNTKFWYGGGIRSKEQAAEMAKYADTIIVGNIIYEDLEKALETATIFRKKTV
What is the function of this protein?
Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP).  This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales.  To a much lesser extent, is also able to use geranylgeranyl diphosphate (GGPP; C20) as the prenyl donor.
What are the official names of this protein?
Heptaprenylglyceryl phosphate synthase, HepGP synthase, Glycerol-1-phosphate heptaprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GGGP/HepGP synthase family. Group I subfamily.
Protein: AIPS_AERPE
Sequence: MGVFNRLRSFYEARIAPTVASFLSRISPDPNIYTLASPVAAAAALPAWLYISPVASLLLIALSLLLDAVDGAVARFTGRVSPLGSFLDSSLDRISDSLYHATLYIAGVHPLIVIAMLSGGLIVPYLRAKGESLGLEVRGRGLMERGERSIAILAILAISIYNLQTALALASAAAVLVWITVIQRMVYIAGELRR
What is the function of this protein?
Catalyzes the formation of archaetidylinositol phosphate (AIP) from CDP-archaeol (CDP-ArOH or CDP-2,3-bis-(O-phytanyl)-sn-glycerol) and 1L-myo-inositol 1-phosphate (IP or 1D-myo-inositol 3-phosphate).  AIP is a precursor of archaetidyl-myo-inositol (AI), an ether-type inositol phospholipid ubiquitously distributed in archaea membranes and essential for glycolipid biosynthesis in archaea.
What are the official names of this protein?
Archaetidylinositol phosphate synthase, AIP synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DEF_CHLTA
Sequence: MIRDLEYYDSPILRKVAAPVTEITDELRQLVLDMSETMAFYKGVGLAAPQVGQSISLFIMGVERELEDGELVFCDFPRVFINPVITQKSEQLVYGNEGCLSIPGLRGEVARPDKITVSAKNLDGQQFSLALEGFLARIVMHETDHLHGVLYIDRMSDKDKTKQFKNNLEKIRRKYSILRGL
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: RL17_BACTN
Sequence: MRHNKKFNHLGRTASHRSAMLSNMACSLIKHKRITTTVAKAKALKKFVEPLITKSKEDTTNSRRVVFSNLQDKIAVTELFKEISVKIADRPGGYTRIIKTGNRLGDNAEMCFIELVDYNENMAKEKVAKKATRTRRSKKSAEAAAPAAVEAPATEEPKAESAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: ACEK_BURM7
Sequence: MNHFPKLLSSQIGFDVAQTILENFDRHYRIFREAAVEAKDLFERADWHGLQRLARERITSYDDRVRECVELLEDEYDAENIDNEVWPQIKLHYIGLLTSHRQPECAETFFNSVCCKILHRAYFNNDFIFVRPAISTEYIENDEPAAKPTYRAYYPGSEGLAATLERIVTNFQLNPPFEDLERDIACIMQAIHDEFGAFDEAVNFQIHVLSSLFYRNKTAYVVGRIINGDRVLPFAVPIRHARAGILALDTVLLRRDQLKIIFSFSHSYFLVDMNVPSAYVQFLRSIMPGKPKAEIYTSVGLQKQGKNLFYRDLLHHLSHSSDRFIVAPGIKGLVMLVFTLPSFPYVFKMIKDHFPPPKDTTREQIMAKYLLVKRHDRLGRMADTLEYSSVALPLARLDDALVRELEKEVPSLIEYEGENLVIKHLYIERRMVPLNLYLQNGSDAEIEHGVREYGNAVKELMQANIFPGDMLYKNFGVTRHGRVVFYDYDEIEYLTDCNVRRVPPPRNDEDEMSGEPWYTVGPHDIFPETYAPFLLGDPRVREHFLAHHADFFDPQLWQDSKDRLLRGELPDFFAYEPALRFCIRYPERFAPGDAADGGKLAAA
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.