PharMolix/UniProtQA huggingface dataset:
Protein: NR2CA_MOUSE
Sequence: MTQSLVCPDTVSRVSSVLNRNSRQFGKKHLFDQDEETCWNSDQGPSQWVSLEFPQCVQITQLQVQFQGGFSSRHSCLEGSRGGEALSKIVDFYPEDTNALQTFSIPTMEVDRLKLTFEDTTDFFGRVVIYHLRVLGEKAG
What is the function of this protein?
May act as a repressor of NR2C2-mediated transactivation by suppressing the binding between NR2C2/TR4 and the TR4-response element in target genes.
What are the official names of this protein?
Nuclear receptor 2C2-associated protein, TR4 orphan receptor-associated 16 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the NR2C2AP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYT_ACIAD
Sequence: MPIITLPNGDQKSFDQPVSVMQVAQSIGPGLAKNTVAGRVNDRLVDACDLITEDATLQIITPKDPEGVEIIRHSCAHLVGHAVKQLFPDVQMVIGPVIEEGFYYDIFSPKPFTLDDMAAIEARMKQLIDQDYDVVKKMTPREQVIQEFTTRGETYKLRLIDDMPEETQMGLYYHQEYVDMCRGPHVPNTKFLKNFKLTKISGAYWRGDAKNEQLQRIYGTAWSDKKELAAYIKRIEEAEKRDHRKIGKALDLFHMQEEAPGMVFWHANGWTIYQALEQYMRKVQQDNGYQEVRTPQIVDFTLWEKSGHAANYAENMFTTHSESRNYAVKPMNCPCHVQVFNQGLKSYRDLPVRLAEFGSCHRNEPSGSLHGIMRVRGFTQDDGHIFCTKEQIGKEVADFIQLTLDVYKDFGFEDVQMKLSTRPEKRVGDDRLWDLAEKSLADALDAAGLEWELQPGEGAFYGPKIEFSLKDCLGRVWQCGTIQCDFNLPIRLDASFVTEDNERDQPVMLHRAILGSFERFIGILIEHYAGFMPPWLAPVQACVMNITDSQAEACQQVVAKLKENGLRAISDLRNEKIGFKIRERTLERIPYLLVLGDREVEEGTVNVRTRSGKNLGTMSIDAFVDLVKSAVAERGRYIVE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABP4_CAEEL
Sequence: MSVPDKFFGRYQLDKSENFDEFLSSKGVNWFVRQMIKLAGLTKIISQNQEAGKYNMENLTSKKNTNYQAWELGKKFEAPGLDGNQHEITFDFKDEILSEHHIRLNEPETSAETYFYTIDDQNQLVMRMENNGIVCRRWFKRVEQK
What are the official names of this protein?
Fatty acid-binding protein homolog 4.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Protein: FBD18_ARATH
Sequence: MEESVKRCRGFSDAREDLMSKLTDALISQVLFYLPTKEAVSTSVLSSRWKSVWLLIPDLDLNSSAFPSNNAFVGFIDKFIDFSKIENSCLHKLKLSIRKEHENDNKSCVTRWIGFVATHKLKHLDVECLLWKKKCLEVMPLTLYITQTLFYLRLHRVLLGNVESISLPCLKTMHLEQNVYANETCLEFFISSCPVLEDLSIVRKVDDNVKVLRVLSQTLTSLFVAFDYGEHRRGFHGYYSLDFGVLIDAPRLKYLKIGDDISRSKIVSNMDSLAKIEIVGLFYIERAFHNKVARNFFIGISRVRDMIISDRAMWFMSFYFLREESTPQFCNLSSLEVKISWSRGINLSMFLDNSPNLKSMVLVIYCKNLEKSVSFSSVPQCLLSSLEFVEIKISRFGIISLGIGIARFFVENSVVLKKLVVHSSRPMRKKSLVAFENLLALPRRSSMCQIISVVDAGSCGGENERCSLAADDAYLLEPSGR
What are the official names of this protein?
FBD-associated F-box protein At5g44490.
Protein: NEMO_RAT
Sequence: MSRHLWKNQLSEMVQPSGGPAEDQDMLGEESSLGKPAMLHLPSEQGTPETLQRCLEENQELRDAIRQSNQMLRERCEELLHFQVSQREEKEFLMCKFQEARKLVERLSLEKLDLRRQREQALEDLEHLKKCQQQMAEDKASVKAQVTSLLGELQESQSRLEAATKERQTLEGRIRAVSEQVRQLESEREVLQQQHSVQVDQLRMQNQSVEAALRMERQAASEEKRKLAQLQAAYHQLFQDYDSHIKSSKGMQLEDLRQQLQQAEEALVAKQELIDKLKEEAEQHKIVMETVPVLKAQADIYKADFQAERHAREKLVERKELLQEQLEQLQREFNKLKVGCHESARIEDMRKRHVETSQPPLLPAPAHHSFHLALSNQRRSPPEEPPDFCCPKCQYQAPDMDTLQIHVMECIE
What is the function of this protein?
Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor.  Its binding to scaffolding polyubiquitin plays a key role in IKK activation by multiple signaling receptor pathways.  Can recognize and bind both 'Lys-63'-linked and linear polyubiquitin upon cell stimulation, with a much highr affinity for linear polyubiquitin.  Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity.  Essential for viral activation of IRF3.  Involved in TLR3- and IFIH1-mediated antiviral innate response; this function requires 'Lys-27'-linked polyubiquitination.
What are the official names of this protein?
NF-kappa-B essential modulator, NEMO, IkB kinase-associated protein 1, IKKAP1, Inhibitor of nuclear factor kappa-B kinase subunit gamma, I-kappa-B kinase subunit gamma, IKK-gamma, IKKG, IkB kinase subunit gamma, NF-kappa-B essential modifier.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Sumoylated NEMO accumulates in the nucleus in response to genotoxic stress.
Protein: DXS1_ZYMMO
Sequence: MFPNDKTPLLDKIKTPAELRQLDRNSLRQLADELRKETISAVGVTGGHLGSGLGVIELTVALHYVFNTPKDALVWDVGHQTYPHKILTGRRDRIRTLRQRDGLSGFTQRAESEYDAFGAAHSSTSISAALGFAMASKLSDSDDKAVAIIGDGSMTAGMAYEAMNNAKAAGKRLIVILNDNEMSISPPVGALSSYLSRLISSRPFMNLRDIMRGVVNRMPKGLATAARKADEYARGMATGGTFFEELGFYYVGPVDGHNLDQLIPVLENVRDAKDGPILVHVVTRKGQGYAPAEAAKDKYHAVQRLDVVSGKQAKAPPGPPSYTSVFSEQLIKEAKQDDKIVTITAAMPTGTGLDRFQQYFPERMFDVGIAEQHAVTFAAGLAAAGYKPFCCLYSTFLQRGYDQLVHDVAIQNLPVRFAVDRAGLVGADGATHAGSFDLAFMVNLPNMVVMAPSDERELANMVHSMAHYDQGPISVRYPRGNGVGVSLEGEKEILPIGKGRLIRRGKKVAILSLGTRLEESLKAADRLDAQGLSTSVADMRFAKPLDEALTRQLLKSHQVIITIEEGALGGFATQVLTMASDEGLMDDGLKIRTLRLPDRFQPQDKQERQYAEAGLDADGIVAAVISALHRNSKPVEVVEMANMGSIARA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase 1, 1-deoxyxylulose-5-phosphate synthase 1, DXP synthase 1, DXPS 1.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: LDLR_RAT
Sequence: MSTADLMLRWAIALLLAAAGVAAEDSCGKNEFQCRDGKCIVSKWVCDGSRECPDGSDESPETCMSVTCRSGEFSCGGRVSRCIPDSWRCDGRTDCENGSDELDCSPKTCSLDEFRCQDGKCISRQFVCDQDWDCLDGSDEAHCAATTCGPAHFRCNSSSCIPSLWACDGDRDCDDGSDEWPQNCGAEDTAAEVVSSPCSSLEFHCGSSECIHRSWVCDGAADCKDKSDEENCAVTTCRPDEFQCADGSCIHGSRQCDREHDCKDMSDELGCINVTQCDGPNKFKCHSGECISLDKVCNSARDCRDWSDEPIKECKTNECLDNNGGCSHICKDLKIGYECLCPSGFRLVDGHQCEDIDECQEPDTCSQLCVNLEGSFKCECRAGFHMDPHTRVCKAVGSIGFLLFTNRHEVRKMTLDRSEYTSLIPNLKNVVALDTEVANNRIYWSDLSQRKIYSAVMDQGTSLSYDAIISGDLHAPDGLAVDWIHGNIYWTDSVPGTVSVADTKGVRRRTLFREKGSRPRAIVVDPVHGFMYWTDWGTPAKIKKGGLNGVDIYSLVTEDIQWPNGITLDLPSGRLYWVDSKLHSISSIDVNGGGRKTILEDEKQLAHPFSLAIYEDKVYWTDVLNEAIFSANRLTGSDVNLVAKNLMSPEDIVLFHNVTQPRGVNWCEATVLPNGGCQYMCLPAPQISAHSPKFTCACPDGMLLAKDMRSCLPEVDTVPTTQGTSTIGPVVTTSAAVSLKRKEDPSATRHKEDPSATRHNEDPSATSTSRQPGDTPELSTVESVTVSSQVQGDMAGRGDEVQRHGVGFLSIFLPIALVALLVFGAILLWRNWRLRNINSINFDNPVYQKTTEDEIHICRSQDGYTYPSRQMVSLEDDVA
What is the function of this protein?
Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis.  In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits.
What are the official names of this protein?
Low-density lipoprotein receptor, LDL receptor.
What is the protein family that this protein belongs to?
Belongs to the LDLR family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Membrane, clathrin-coated pit. Golgi apparatus. Early endosome. Late endosome. Lysosome. Note=Rapidly endocytosed upon ligand binding.
Protein: GCH1_COXBR
Sequence: MSNTIADHVKAILIALGEDPNREGLRDTPKRYEKALEHLTKGYHEKLPSVVKKAVFQSGMDEMVILKDIELYSLCEHHLLPFIGRCHVAYLPSGKIIGISKLARIVDMFAKRLQVQENLTKQIAEAILTATEAKGVGVIIEAKHLCMMMRGVEKQNSEMTTSVMLGTFRKDDRTRSEFLSLIRK
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: RR2_PSINU
Sequence: MQQTNWNIELIEMLKAGVHFGHQTRKWNPKMAPHIFMERKGVHILNLIQTARFISEACDLVYNAASEGKQFLLVGTKPRIAHLISSAAIKARCHYVNYKWIGGMLTNWSTIEKRLQKLRSLEIRKRMGGLDNLSKEEAAILRGQLSKLHKYLGGILYMKNLPDIVIIVDQHKELTAIRECMILDIPTICVVDTDCDPDLTNIPIPANDDAQSSIRWILNQLTLAIREGRCHSMSPKNSK
What are the official names of this protein?
30S ribosomal protein S2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SCRK2_ORYSJ
Sequence: MAPLGDGAAAAAAAEPNLVVSFGEMLIDFVPDVAGVSLAESGGFVKAPGGAPANVACAISKLGGSSAFVGKFGDDEFGHMLVDILKKNGVNAEGCLFDEHARTALAFVTLKSNGEREFMFYRNPSADMLLTEAELNLDLIRRAKIFHYGSISLITEPCRSAHVAAMRAAKSAGILCSYDPNVRLPLWPSEDAARAGILSIWKEADFIKVSDDEVAFLTQGDANDEKNVLSLWFDGLKLLIVTDGEKGCRYFTKDFKGSVPGFSVNTVDTTGAGDAFVGSLLVNVAKDDSIFHNEEKLREALKFSNACGAICTTKKGAIPALPTVAVAQELISKAAN
What is the function of this protein?
May play an important role in maintaining the flux of carbon towards starch formation in endosperm.  May also be involved in a sugar-sensing pathway.
What are the official names of this protein?
Fructokinase-2, Fructokinase II, OsFKII.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family.
Protein: OPS6_DROME
Sequence: MASLHPPSFAYMRDGRNLSLAESVPAEIMHMVDPYWYQWPPLEPMWFGIIGFVIAILGTMSLAGNFIVMYIFTSSKGLRTPSNMFVVNLAFSDFMMMFTMFPPVVLNGFYGTWIMGPFLCELYGMFGSLFGCVSIWSMTLIAYDRYCVIVKGMARKPLTATAAVLRLMVVWTICGAWALMPLFGWNRYVPEGNMTACGTDYFAKDWWNRSYIIVYSLWVYLTPLLTIIFSYWHIMKAVAAHEKAMREQAKKMNVASLRNSEADKSKAIEIKLAKVALTTISLWFFAWTPYTIINYAGIFESMHLSPLSTICGSVFAKANAVCNPIVYGLSHPKYKQVLREKMPCLACGKDDLTSDSRTQATAEISESQA
What is the function of this protein?
Visual pigments are the light-absorbing molecules that mediate vision.  They consist of an apoprotein, opsin, covalently linked to cis-retinal.
What are the official names of this protein?
Opsin Rh6, Rhodopsin Rh6, long-wavelength.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: UBP11_RAT
Sequence: MAAVAADPAAAAVPASAEDRETQPEAMPDLDQQWRQIGNGRERPLRAGESWFLVEKHWYKQWEAYVKGGDQDASTFPGSINNSGLFEDQISWHLRERLVEGDDYVLLPAPAWNYLVSWYGLKDDQPPIERKVIELPGIRKVEVYPIELLLVQHSDMETALTIQFSYSDSVDLVLQTAREQFLVEPQEDTRLWTKNSEGSLDRLCNTQITLLDACLETGQLVIMETRNKDGTWPSAQLCGMNNMPDEDEDFQGQPGICGLTNLGNTCFMNSALQCLSNVPQLTEYFLNNRYLEELNFRNPLGMKGELAEAYADLVKQTWSGYHRSIVPNVFKNKVGHFASQFLGYQQHDSQELLSFLLDGLHEDLNRVKKKEYVELCNGAGRPDLEVAQEAWQNHKRRNDSVIVDTFHGLFKSTLVCPDCGNVSVTFDPFCYLSVPLPVCSRRVLEVFFVPMDPRRKPEQHRVVVPKKGNISDLCVALSTHTSVAPDKMIVADVFSHRFYKLYQLEDPLSGILDRDDIFVYEVTGRIEPVEGSRDDIVVPVYLRERTPSRDYNNSYYGLILFGHPLLVSVPRDRFSWEGLYNILMYRLSRYVTKPTSDDDDGDEKGDENEDEDVEDDSSSEEEKEEMSGPTDNDGTQESEQEQAGTSSGVTGRCPSLLDNSLHTSQWPPRRRRKQLFTLQTVNSNGTSDRTTSPEEAQTQPYIAMDWEPEMKRRYYDEVEAEGYVKHDCVGYMLKKNPVQLKECIKLFTTVETLEKENPWYCSSCKQHQLATKKLDLWMLPEVLIIHLKRFSFSKFSREKLDTLVQFPIRDLDFSEFVIKPKNESAPDLYKYDLIAVSNHYGGMRDGHYTTFACNKDSGQWHYFDDNSVSPVNENQIESKAAYVLFYQRQDVGRRQSQTASSETPTSPASSSTPNSDIMDVN
What is the function of this protein?
Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains.  Inhibits the degradation of target proteins by the proteasome.  Cleaves preferentially 'Lys-6' and 'Lys-63'-linked ubiquitin chains.  Has lower activity with 'Lys-11' and 'Lys-33'-linked ubiquitin chains, and extremely low activity with 'Lys-27', 'Lys-29' and 'Lys-48'-linked ubiquitin chains (in vitro).  Plays a role in the regulation of pathways leading to NF-kappa-B activation.  Plays a role in the regulation of DNA repair after double-stranded DNA breaks.  Acts as a chromatin regulator via its association with the Polycomb group (PcG) multiprotein PRC1-like complex; may act by deubiquitinating components of the PRC1-like comple.  Promotes cell proliferation by deubiquitinating phosphorylated E2F1x.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 11, Deubiquitinating enzyme 11, Ubiquitin thioesterase 11, Ubiquitin-specific-processing protease 11.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Chromosome. Note=Predominantly nuclear. Associates with chromatin.
Protein: ISPE_METRJ
Sequence: MTLLADRAPAKVNLTLHVLGRRVGDGYHVLESLVAFAGTADRLTLDPDAPLGLTVSGPTAGPAGPTDDNLVLRAARGLAARVPGLRAGAFHLVKRLPVAAGIGGGSSDAAAALRLLARLNGLPLDHAAVGAVARETGADVPVCLDPRARMMRGAGEEIGAALGLEPLPAVLINPGVPVPTAPVFRALGLSVGQDLAGAPHPTIPQATATDTLLQALAGARNDLEAPALTVAPVIGDALAALRAQGCRLARMSGSGATVFALFADRRAAVRAAAALRAAHPGWWVAPTFLR
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: ASPC1_MOUSE
Sequence: MAAPAGGGGSAVSVLAPNGRRHTVKVTPSTVLLQVLEDTCRRQDFNPSEYDLKFQRTVLDLSLQWRFANLPNNAKLEMVPVSRSREGPENIVRIAFQLDDGSRLQDAFCSRQTLWELLSHFAQTRERLQQLGEKTPVCVYMRNEVTGRAALQNTTLQSLGLTGGSATIRFVIKQCDTAGKQESIAVRSKAPGSPVSSLSADQASSSTLLPLNSGEFSRGDLNHEGDANTSGTGLEGGPKPTDAQTKQSTSEPASAPFVPFSGGGQRLGGPSASLRPLTSPSANSSKSFSGPGGPSKPKKPKPGEEPQQEPEPPVDRDPVVYHPDLEDLLQPWPAEVPDEFFEVTVDDVRRRLAQLKSERKRLEEAPLVTKAFREAQMKEKLERYPKVALRVLFPDRYILQGFFRPSETVGDLRDFVRSHLGNPELSFYLFIAPPKMVLDDHTLTLFQANLFPAALVHFGAEEPTGLYLEPGLLEHTVSPSTADVLVARCMSRASGSPPLLPAPDPVSLESEPIAEDGALGPPEPIQGTAQPVKRSLGKVPKWLKLPASKR
What is the function of this protein?
Enhances VCP methylation catalyzed by VCPKMT (By similarity).  Tethering protein that sequesters GLUT4-containing vesicles in the cytoplasm in the absence of insulin.  Modulates the amount of GLUT4 that is available at the cell surface.
What are the official names of this protein?
Tether containing UBX domain for GLUT4, Alveolar soft part sarcoma chromosomal region candidate gene 1 protein homolog.
What are the subcellular locations of this protein?
Endomembrane system; Peripheral membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Peripheral membrane protein. Cytoplasm. Nucleus.
Protein: ENPP4_DANRE
Sequence: MQISAYLCALIACCGLTLSAPTANNKSSSEAPPLLLVSFDGFRADYLNKYSFPNLEKFFSDGVLVHELTNVFTTKTFPNHYSLVTGLYAESHGMLASIMYDPVAKKHFSIKNDSDPFWWDEATPIWVSVEESGYHAASAMWPGSDVNIQNHTLKYTFKYDSRVSFKERLGNITQWMTTDKSLKFASLYWEEPDFSGHTYGPDNTTEMARVLKEVDGHVGYLMEELDRMELWGKINVIITSDHGMAQCSEERIIRLDDCVSPSSYTLVDLTPVAAIIPLEDKTTVYNNLSSCHVHLKAYMKNDVPDRLHYKNNERIQPIILVADEGWTIVKNGRLPRLGDHGYDNTLPSMHPFLAAHGPAFRKGYKMSSFNSVDLYPLMCHLIGIPPKANNGSFAHVRCTLVNEQCGELALAVGLVMGVLIILTTFTCLFKLMKNRNVSSPRPFARLELDDDGDDEPLLE
What is the function of this protein?
Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP.  Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells.  Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors (By similarity).
What are the official names of this protein?
Bis(5'-adenosyl)-triphosphatase enpp4, AP3A hydrolase, AP3Aase, Ectonucleotide pyrophosphatase/phosphodiesterase family member 4, E-NPP 4, NPP-4.
What is the protein family that this protein belongs to?
Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: FIS_SALPC
Sequence: MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.
Protein: YVDE_BACSU
Sequence: MATLSDVAKKANVSKMTVSRVINHPETVTDELKKLVHSAMKELNYIPNYAARALVQNRTQVVKLLILEEMDTTEPYYMNLLTGISRELDRNHYALQLVTRNSLNIGQCDGIIATGLRKNDFEGVIKAFEKPLVVFGQNEMGYDFIDVNNEKGTFMATRHVMGLGEREVVFFGIDLDEPFERAREQGYIRAMNKSFKKSNMFRIDNSSKKSECLARELLKSMDNQAAFVCASDRIALGVIRAAQSLGKRIPEDVAVTGNDGVFLDRISSPRLTTVRQPVVEMGEACAKMLLKKMNEDGAAQGSLFFEPELIVRESTL
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator YvdE.
Protein: RL5_MYCTO
Sequence: MTTAQKVQPRLKERYRSEIRDALRKQFGYGNVMQIPTVTKVVVNMGVGEAARDAKLINGAVNDLALITGQKPEVRRARKSIAQFKLREGMPVGVRVTLRGDRMWEFLDRLTSIALPRIRDFRGLSPKQFDGVGNYTFGLAEQAVFHEVDVDKIDRVRGMDINVVTSAATDDEGRALLRALGFPFKEN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: RL13_WOLTR
Sequence: MKTFFLKEGQIDKKWFVINAEGLVVGRLAAFVATLLRGKHKPEYTPHMDCGDNIIIINAEKVHFTGKKFKEKVYYKHTGYPGGLKKTTPNNVLNGKFPERVIKMAVKRMLDDGPMARKRFGNLYVYSGPEHKHQGQQPKKIDFASLNRKNKK
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: PETD_AMPOP
Sequence: MVVRLPYVKGSILCSALAKGCGHNYYGEPAWPNDILYIFPVVILGTISFSLGLGVIENQAIGEPANPFATPLEILPEWYFFPTFNLLRILPDKLVGVLSLASVPVILVLTAFIENINRYQNPFRRPVASLVYLTSTCYALWLGYGSVLGISEALPFV
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 4, 17 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetD subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: LEUD_ACTSZ
Sequence: MAGLKQHSGLVVPLDAANVDTDAIIPKQFLQAITRVGFGKHLFHEWRYLDAEETRPNPEFVLNFPQYQGATILLARKNLGCGSSREHAPWALADYGFKVMIAPSFADIFYNNSLNNHMLPIKLSEQEVDEIFHWVWANPGKQIHVDLEAKTVTVGDKVYHFELDEFRRHCLLEGLDNIGLTLQHEDAIAAYEKKIPAFLR
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: PYRC_STAAC
Sequence: MKLIKNGKVLQNGELQQADILIDGKVIKQIAPAIEPSNGVDIIDAKGHFVSPGFVDVHVHLREPGGEYKETIETGTKAAARGGFTTVCPMPNTRPVPDSVEHFEALQKLIDDNAQVRVLPYASITTRQLGKELVDFPALVKEGAFAFTDDGVGVQTASMMYEGMIEAAKVNKAIVAHCEDNSLIYGGAMHEGKRSKELGIPGIPNICESVQIARDVLLAEAAGCHYHVCHVSTKESVRVIRDAKRAGIHVTAEVTPHHLLLTEDDIPGNNAIYKMNPPLRSTEDREALLEGLLDGTIDCIATDHAPHARDEKAQPMEKAPFGIVGSETAFPLLYTHFVKNGDWTLQQLVDYLTIKPCETFNLEYGTLKENGYADLTIIDLDSEQEIKGEDFLSKADNTPFIGYKVYGNPILTMVEGEVKFEGDK
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: PANB_SALRD
Sequence: MPRVTTKTVQEMKEEGVPIAALTAYDYTSARLLDRAGADVLLVGDSAANVMAGHETTLPMTLDQMIYHAQCVVRGIDRSLVVVDLPFGAYQGDPTEALDSAIRVMKEAGAHAVKLEGGAPVVEAVERMVTAGIPVMGHLGLTPQSIYDYGTYQVRARDEEEADELRADAKRLEEAGCFAVVLEKIPAELAAEVTASLSIPTIGIGAGDQTDGQVLVSHDALGLSTDFEPRFVRRYARLDETIIDAIGAYVSDVRDRSFPDEDESY
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_NOSS1
Sequence: MAIISSKKQPPEPNGQPNKRPESAPSVPKEKVLQPEAAIDEQGKQEESIRPQRFADYIGQKDLKDVLDIAIKAAKSRGEVLDHLLLYGPPGLGKTTMAMILASEMGVNYKITSAPALERPRDIVGLLVNLKPGDILFIDEIHRLSRMTEEILYPAMEDYRLDITVGKGSSARIRSIPLSKFTLVGATTRVGALTSPLRDRFGLIQKLRFYEVDELSQIVLRSAQLLQTQVTDDGATEIARRSRGTPRIANRLLKRVRDYAQVKSCAEVSQNIAAEALQLFQVDPCGLDWTDRRMLSVIIEQFNGGPVGLETIAAATGEDTQTIEEVYEPYLMQIGYLSRTPRGRTATKAAYKHMGFTPPNEQLSLL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: SMZ_ARATH
Sequence: MLDLNLKIFSSYNEDQDRKVPLMISTTGEEESNSSSSSTTDSAARDAFIAFGILKRDDDLVPPPPPPPHKETGDLFPVVADARRNIEFSVEDSHWLNLSSLQRNTQKMVKKSRRGPRSRSSQYRGVTFYRRTGRWESHIWDCGKQVYLGGFDTAYAAARAYDRAAIKFRGLDADINFVVDDYRHDIDKMKNLNKVEFVQTLRRESASFGRGSSKYKGLALQKCTQFKTHDQIHLFQNRGWDAAAIKYNELGKGEGAMKFGAHIKGNGHNDLELSLGISSSSESIKLTTGDYYKGINRSTMGLYGKQSSIFLPMATMKPLKTVAASSGFPFISMTSSSSSMSNCFDP
What is the function of this protein?
Probably acts as a transcriptional activator.  Binds to the GCC-box pathogenesis-related promoter element.  May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).  Repressor of flowering.
What are the official names of this protein?
AP2-like ethylene-responsive transcription factor SMZ, Protein SCHLAFMUTZE.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. AP2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS16_CITK8
Sequence: MVTIRLARHGAKKRPFYQVVVTDSRNARNGRFIERVGFFNPIASEKEEGTRLDLDRIAHWVGQGATISDRVAALIKAANKAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.