PharMolix/UniProtQA huggingface dataset:
Protein: PALF_MAGO7
Sequence: MGGSSASRNQSSLLEDTHTSRSLISRLFSRSKTRHITDFHIRPVDPHRKYAKGDHVTGAVVLTVLRPIRITHLTVALHGFVKVFKSPNAAHEATINTAQIASGVTNRTRYLGNGLASLFQDEQVLSADGKLEAGRYEFNFDLVFPSKVNLPTSIDFERGTISYMISATLTRPTSITPTTVCDRKIYLVEKVDIGSIPAPRPRTISLEPISRRTRRRRTDRPSTLGGADRGSSLGDSHDVTSSDLDSSRAPESVAAESNIANDAAFEGQQAPQSPTRTEMPDVMSEVSTESAITSSSAGASVGYKVSEATGSSSGSQFGARTPTVEEKTITASVEMLKGGCLPGDFVPVKISVHHIKRIKSVHGVIVTLYRQGRIDSAPPISSFQGLSKEDVRRLEKEEYFPRSKTGLSGLSLSSAGSCSVFRKDLSQAFGPLIIDPITLDASVTISVRVPEDVFPTIKGVPGELISFKYQMEVIVDLGGKLASQISSVQSKAGGISAGGAMPSARNPYESGGSSIMGSWGNSIIDTDQLRRHKGVISVVFEVPVGSVDSSRQRTRGGSLRPNPQARQPSQATESSQIPTVGYGPEDKQRAQSEPAGQEDYVHSHGSQGNGPMGPSTEYVPSPYYTPHDPRQQHAPIYIPPPDVPNDMGLSEKERARRAEQRLLPSQPPAAPFASTLSETTLEDIYNVEDDAAAGPSSAPIVGNSNGVATAPTLDEVESGEAAVGNSEDKLERERHRLLQEASAPPDFPEDYDTGDPGPSNQGPVTSATAPALSFQPSAPILSEDDEDPGSSYFNQHTSTGDYMGAGALGRPITAPHEPLPRYQR
What is the function of this protein?
Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH.
What are the official names of this protein?
pH-response regulator protein palF/RIM8.
What is the protein family that this protein belongs to?
Belongs to the arrestin family. PalF/RIM8 subfamily.
Protein: ZN320_HUMAN
Sequence: MALSQGLLTFRDVAIEFSQEEWKCLDPAQRTLYRDVMLENYRNLVSLDISSKCMMNTLSSTGQGNTEVIHTGTLQRQASYHIGAFCSQEIEKDIHDFVFQWQEDETNDHEAPMTEIKKLTSSTDRYDQRHAGNKPIKGQLESRFHLHLRRHRRIHTGEKPYKCEECEKVFSCKSHLEIHRIIHTGEKPYKCKVCDKAFKHDSHLAKHTRIHRGDKHYTCNECGKVFDQKATLACHHRSHTGEKPYKCNECGKTFSQTSHLVYHHRLHTGEKPYKCNECGKTFARNSVLVIHKAVHTAEKPYKCNECGKVFKQRATLAGHRRVHTGEKPYRCEECDKVFSRKSHLERHRRIHTGEKPYKCKVCDKAFRSDSRLAEHQRVHTGERPYTCNECGKVFSTKAYLACHQKLHTGEKLYECEECDKVYIRKSHLERHRRIHTGEKPHKCGDCGKAFNSPSHLIRHQRIHTGQKSYKCHQCGKVFSLRSLLAEHQKIPFGDNCFKCNEYSKPSSIN
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 320.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NRLA_ALCFA
Sequence: MQTRKIVRAAAVQAASPNYDLATGVDKTIELARQARDEGCDLIVFGETWLPGYPFHVWLGAPAWSLKYSARYYANSLSLDSAEFQRIAQAARTLGIFIALGYSERSGGSLYLGQCLIDDKGQMLWSRRKLKPTHVERTVFGEGYARDLIVSDTELGRVGALCCWEHLSPLSKYALYSQHEAIHIAAWPSFSLYSEQAHALSAKVNMAASQIYSVEGQCFTIAASSVVTQETLDMLEVGEHNASLLKVGGGSSMIFAPDGRTLAPYLPHDAEGLIIADLNMEEIAFAKAINDPVGHYSKPEATRLVLDLGHREPMTRVHSKSVIQEEAPEPHVQSTAAPVAVSQTQDSDTLLVQEPS
What is the function of this protein?
Nitrilase that acts mostly on arylacetonitriles.
What are the official names of this protein?
Nitrilase, arylacetone-specific, Arylacetonitrilase.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.
Protein: SYR_PROMH
Sequence: MNIQAFLSEKISMAMSAAGAPADSEPLVRQSAKVQFGDYQANGVMGAAKKMGIPPRQLAEKILEHLDITDIADKVEIAGPGFINIFLSPVWVAQQAEFALADEHLNITKVTPETIVIDYSSPNVAKQMHVGHLRSTIIGDASARTLSFLGHNVIRANHLGDWGTQFGMLIAYLEKKQNENAADMALADLEEFYREAKKCYDEDEVFAERARNYVVRLQGGDEYCRTMWRKLVDITMQQNQLTYQRLNVTLTEDDIMGESLYNPMLPGIVADLKAKGLAVESEGATVVFLDEYKNKEGEPMGVIIQKKDGGYLYTTTDIACAKYRHEQLHANRVLYYIDSRQHQHLMQAWTIVRKAGYIPDSMSLEHHMFGMMLGKDGRPFKTRSGGTVRLTDLLDEAHERALTLIREKNPDMDEEELNNIARVVGIGAVKYADLSKNRTTDYIFDWDLMLSFEGNTAPYMQYAYTRVASIFKRADIDESALTQPISLTQPHEKQLALRLVQFDETITQVAREGTPHVMCAYLYDLAQSFSGFYENCPILSAEDDNVRQSRLKLARLTARTLKQGLETLGIETVDRM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXS_MYCSK
Sequence: MLEQIRGPADLQHLSQSALSELAGEIRQFLIHKVAATGGHLGPNLGVVELTLALHRVFDSPHDPLIFDTGHQAYVHKMLTGRSHEFDSLRKKDGLSGYPSRSESEHDWVESSHASAALSYADGLAKAFELTGHRNRHVVAVVGDGALTGGMCWEALNNIAAARRPVVIVVNDNGRSYAPTIGGFADHLAALRLQPGYERVLEEGRKAVRGLPVIGEFCYQCMHSVKAGIKDALSPQVMFTDLGLKYVGPIDGHDEHAVESALRHARGFNAPVIVHVVTRKGMGYAPAENDEAEQMHACGVIDVATGRATKVAAPGWTSSFSEALIDYGAKRRDIVAITAAMPGPTGLSAFRDRFPDRFFDVGIAEQHAMTSAAGLAMGGLHPVVAIYSTFLNRAFDQLMMDVALHKLPVTLVLDRSGVTGPDGASHNGMWDLSVLGIVPGMRVAAPRDGARLREELGEALDVNDAPTAIRFPKGDVGEDIPAVRRHRGVDVLAEPADGLSDDVLLVAVGPFASMALTVAERLRKQGIGVTVVDPRWVLPVPEVLTEFAAAHKLVVTVEDNGLHGGIGSSVSAALRHAEVDVPCRDVGLPQQFFDHASRGEVLADVGVTDRNISRQITGWVAALGATPADADEVSERLD
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: PSBH_CHAVU
Sequence: MATQIVEDTIKSKGRRTDVGDILKPLNSEYGKVAPGWGTTVLMGIFMALFAVFLVIILEIYNASVLLDGISVSWASLV
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein H, PSII-H, Photosystem II 10 kDa phosphoprotein.
What is the protein family that this protein belongs to?
Belongs to the PsbH family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: DFRA_SYNY3
Sequence: MEVNHWIAMADCFFVTGGTGFVGANLVRHLLEQGYQVRALVRASSRPDNLQNLPIDWVVGDLNDGDLHQQMQGCQGLFHVAAHYSLWQKDREALYRSNVLGTRNILACAQKAGIERTVYTSSVAAIGVKGDGQRADESYQSPVEKLIGAYKQSKYWAEQEALTAAQQGQDIVIVNPSTPIGPWDIKPTPTGEIILRFLRRQMPAYVNTGLNLIDVRDVAAGHLLAWQRGKTALTRGDRYILGHENISLQGILAHLSTITGLPAPKNTVPLWLPLTFAWVEEKVLAPLGRSPSVPMDGVKMSAQEMYYDASKAVQELGLPQSSIKQALADAVHWFQNHGYVKTQ
What are the official names of this protein?
Putative dihydroflavonol 4-reductase, DFR, Dihydrokaempferol 4-reductase.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.
Protein: PYRC_ARCFU
Sequence: MIRGKVFYKGEFVEAGIEVENGRIKRIGKLVEGKEVKGVILPAGIDVHVHLRDFAEKRKETIETGTLSALHGGICLVVDQPNTKPPVDDAETYFRRMGKAEKSVYVDYALNLALTNSNHGKIGSIMRKISERYFVPAVGEVFIQHDSEDLQIDYETLSSVYKRFEGVVFTIHAEDPAYVARGSPNFVFRRREAEVLAVERLVELGKFHFCHISTKDSAKEILNSNSTYEVTPHHMLLSVEDYGRLGNLVNVNPPLREREDVEWLFRNFHRIDVLASDHAPHTLEDKEAGASGFPGVETMYPLFVNLASKGYISFKTLVEKIASNPARIFGFKGYGEIEVGNYANFAVFDLKKVDEIRAERLHSKCGWTPFEGFEAVFPDKVYLRGKELLENEMKAGNVLKKRV
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: KDPB_PHOLL
Sequence: MTNKQQTLFEPVLIRNALMDSVKKCHPAAQWRNPVMFVVYLGSGLTTILWIAMLAGQFKGNALFTGNIALWLWFTVLFANFAEALAEGRSKAQAASLKGVRKTSWATKLHSANRNGSREKAPSDSLRKGDIVIIEAGETIPCDGEVIEGGASVDESAITGESAPVIRESGGDFSSVTGGTHVLSDWLVVECSVNPGETFLDRMISMVEGAKRRKTPNEIALTILLTALTIIFLLVCVTLLPFSIFSVEINHSGQPITVTVLIALLVCLIPTTIGGLLSAIGVAGMSRMLSANVIATSGRAVEAAGDVDVLLLDKTGTITLGNRQASQFLPVPGITEQRLADAAQLSSLADETPEGRSIVILAKQRFNLRERDLRSLNATFVPFSAMTRMSGVNVENRMIRKGAVDAIRRHIEANHGKFPEAVEILVQTVARKGGTPLVVAENQQVLGVVALKDIVKGGIKERFSEMRRMGIKTVMITGDNRLTAAAIAAEAGVDDFLAEATPEAKLALIRQYQSEGRLVAMTGDGTNDAPALAQADVAVAMNSGTQAAKEAGNMVDLDSNPTKLIEVVHIGKQMLMTRGSLTTFSIANDIAKYFAIIPAAFAVTYPQLNILNIMHLHSPTSAVLSTVIFNALIIVFLIPLALKGVSYRPMNASALLRRNLWIYGLGGLIAPFIGIKLIDLLLTLLILK
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
What are the official names of this protein?
Potassium-transporting ATPase ATP-binding subunit, ATP phosphohydrolase [potassium-transporting] B chain, Potassium-binding and translocating subunit B, Potassium-translocating ATPase B chain.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CVNH_TUBBO
Sequence: MSYADSSRNAVLTNGGRTLRAECRNADGNWVTSELDLDTCIGNPNGFLGWGMQNFSHSSEDIKLEEGGRKLTCRPKTVDGGFRERQGIDLNRIQNVNGRLVFQ
What is the function of this protein?
Mannose-binding lectin.
What are the official names of this protein?
Cyanovirin-N homolog, CV-N homolog.
What is the protein family that this protein belongs to?
Belongs to the cyanovirin-N family.
Protein: HIS4_AERS4
Sequence: MIIPAIDLINGQVVRLYQGDYDQKTEYSSSPQARFDEYVSQGAVQLHLVDLDGAKETQARQLPLLTQLLSATEAPVQVGGGVRTEQDVADLLAAGASRVVIGSTAVKSPDLVASWMEKYGPEQIVLALDVNIDAQGNRHIAVAGWQENSGVTIEALIERFLPAGLKHVLCTDISRDGTLSGTNVELYRDLCARYPSVGFQASGGIGGIADIEALKGTGVKGIILGRALLEGKFSVGDAIACWANGTQD
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_BUCBP
Sequence: MIGIREIRSKMKSINNTKKITKAMEMVSISKLRKIKKRMCSSRPYFNIINQVISHVITGNLEHYHTYFNQRNVKRIGVIIVSTDRGLCGNLNTLLFKKVLEVLTEHINEHILNNLFVIGTKALTFFKSFTNNIVFSLSNLKNDFKIIDLMEMIRISLEMYISGKIDKLFLAYNKFNSTIIQTPTLVQLLPILKPKLGKKEVKKTWDYIYESNSKVLLNVVLNRYIEFQIYQSILENLVCEQASRMLAMKQATDNSADLLKALQMNYNKVRQSSITQELTEIISGAAAVSLN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: LOLD_FRATH
Sequence: MNDVVLSCKNVSKKYTEFKTDIAILKDVNLEIKKGEKVAILGLSGSGKTTLLNVLGGLDKCSAGEVYLMGERFDNQSVNKRAKMRNKHLGFIYQLHHLLPEFTAIENVMIPLAITKKYTKKESIKLANEILKKVGLDHRADHKPAELSGGERQRVAIARALVTNPNCILADEPTGNLDSQRSESIFALMQQLSDDFGTSFVIVTHDEKLASRMNKIYRLVDGELELVINSN
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PCBP3_HUMAN
Sequence: MGEGDAFWAPSVLPHSTLSTLSHHPQPQFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPKGATIPYRPKPASTPVIFAGGQAYTIQGQYAIPHPDQLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLINARLTSEVTGMGTL
What is the function of this protein?
Single-stranded nucleic acid binding protein that binds preferentially to oligo dC.
What are the official names of this protein?
Poly(rC)-binding protein 3, Alpha-CP3, PCBP3-overlapping transcript, PCBP3-overlapping transcript 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCD12_MOUSE
Sequence: MMLLLPFLLGLLGPGSYLFISGDCQEVATVMVKFQVTEEVPSGTVIGKLSQELRVEERRGKAGDAFQILQLPQALPVQMNSEDGLLSTSSRLDREKLCRQEDPCLVSFDVLATGASALIHVEIQVLDINDHQPQFPKDEQELEISESASLHTRIPLDRALDQDTGPNSLYSYSLSPSEHFALDVIVGPDETKHAELVVVKELDRELHSYFDLVLTAYDNGNPPKSGISVVKVNVLDSNDNSPVFAESSLALEIPEDTVPGTLLINLTATDPDQGPNGEVEFFFGKHVSPEVMNTFGIDAKTGQIILRQALDYEKNPAYEVDVQARDLGPNSIPGHCKVLIKVLDVNDNAPSILITWASQTSLVSEDLPRDSFIALVSANDLDSGNNGLVHCWLNQELGHFRLKRTNGNTYMLLTNATLDREQWPIYTLTVFAQDQGPQPLSAEKELQIQVSDVNDNAPVFEKSRYEVSTWENNPPSLHLITLKAHDADLGSNGKVSYRIKDSPVSHLVIIDFETGEVTAQRSLDYEQMAGFEFQVIAEDRGQPQLASSISVWVSLLDANDNAPEVIQPVLSEGKATLSVLVNASTGHLLLPIENPSGMDPAGTGIPPKATHSPWSFLLLTIVARDADSGANGELFYSIQSGNDAHLFFLSPSLGQLFINVTNASSLIGSQWDLGIVVEDQGSPSLQTQVSLKVVFVTSVDHLRDSAHEPGVLSTPALALICLAVLLAIFGLLLALFVSICRTERKDNRAYNCREAESSYRHQPKRPQKHIQKADIHLVPVLRAHENETDEVRPSHKDTSKETLMEAGWDSCLQAPFHLTPTLYRTLRNQGNQGELAESQEVLQDTFNFLFNHPRQRNASRENLNLPESPPAVRQPLLRPLKVPGSPIARATGDQDKEEAPQSPPASSATLRRQRNFNGKVSPRGESGPHQILRSLVRLSVAAFAERNPVEEPAGDSPPVQQISQLLSLLHQGQFQPKPNHRGNKYLAKPGGSSRGTIPDTEGLVGLKPSGQAEPDLEEGPPSPEEDLSVKRLLEEELSSLLDPNTGLALDKLSPPDPAWMARLSLPLTTNYRDNLSSPDATTSEEPRTFQTFGKTVGPGPELSPTGTRLASTFVSEMSSLLEMLLGQHTVPVEAASAALRRLSVCGRTLSLDLATSGASASEAQGRKKAAESRLGCGRNL
What is the function of this protein?
Cellular adhesion molecule that may play an important role in cell-cell interactions at interendothelial junctions (PubMed:9651350).  Acts as a regulator of cell migration, probably via increasing cell-cell adhesion (By similarity).  Promotes homotypic calcium-dependent aggregation and adhesion and clusters at intercellular junctions (PubMed:9651350).  Unable to bind to catenins, weakly associates with the cytoskeleton (PubMed:9651350).
What are the official names of this protein?
Protocadherin-12, Vascular cadherin-2, Vascular endothelial cadherin-2, VE-cad-2, VE-cadherin-2.
What are the subcellular locations of this protein?
[Protocadherin-12]: Cell membrane; Single-pass type I membrane protein. Cell junction. SUBCELLULAR LOCATION: [Protocadherin-12, secreted form]: Secreted. Note=The secreted form is produced following cleavage by ADAM10.
Protein: WCAF_ECOLI
Sequence: MQDLSGFSVPKGFRGGNAIKVQLWWAVQATIFAWSPQVLYRWRAFLLRLFGAKIGKNVVIRPSVKITYPWKLTLGDYAWVGDDVNLYTLGEITIGAHSVISQKSYLCTGSHDHASQHFTINATPIVIGEKCWLATDVFVAPGVTIGDGTVVGARSSVFKSLPANVVCRGNPAVVIRERVETE
What are the official names of this protein?
Putative colanic acid biosynthesis acetyltransferase WcaF.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: GLNE_PASMU
Sequence: MSFPLAHVDATLNQLAKQLIAHFPEQYQDQIFQHIATDKEKPTSNIGQLRYAIAMSDFFAETLQKQPHFLHQCWQQCPRLQDCEQYAERLTPLLAQVENEEQLYKVLRQFRHREMAKLSFCQSLNLGSVEDIFIRLSQLAESVIIGARDWLYQRACAEMGTPVDEQGTPLQLYILGMGKLGGFELNFSSDIDLIFTYASNGETVGARRSIDNAKFFTRLGQRLINALDQYTCDGFVYRTDMRLRPFGENGALALSFAAMELYYQEQGRDWERYAMIKGRILGANAQDPHVNTLQQLLRPFVYRRYIDFSVLQALRDMKHKIEREVRRRGLVDNIKLGAGGIREIEFIVQVFQLIRGGRESALQQPALLKVLPEISALELISAQQQEDLRQAYLFLRRTENILQAIHDQQTQQLPENTLDQQRLVLATQRFTQWDTQNKLETVTYPIHDWASFCEVLQQHQQNVRTVFDHLIGEEKEELSETETLWHDFLENEIEESEIEQMLIEHHIEERDFHEIIEKLMQFRNEVTRRPIGTRGRIALTQVMPTLLPQIFAHTAYLHLLPRMLNIVDKILTRTTYLELLVENPQALTQLIELCAQSRMIAEQVARHPILLDELLDRNALLNPPPYDHYASELRQYLLRLTPDDEEQMIDGLRQFKQATLLRIAAADILGALPVMKVSDHLTFLAEAIIHVVVELAWQQVTTRFGTPAHLAEGEKGFLVIGYGKLGGIELGYKSDLDLVFLYQSDEQSQTCGGKRSIESNQFYLRLAQKIISIFSINTFAGVLYEVDMRLRPSGESGLLCSSISAFKAYQLHDAWTWEKQALVRSRAIYGEARLQTEFNAIRAEVLSAPRDLATLQQDVVAMRQKMYAHLAHPDSDTFNIKTDRGGITDIEFIAQYLVLAHAPQNPALTRWSDNVRIFEIMAESAVISQEICDQLKQCYVDLRNRIHHLNLLGELSIVPQTEFQTERQFIQTIWHRLFEHNDKYEE
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia.  When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity.  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity.  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.
Protein: Y264_CERS4
Sequence: MVEPVQEYRLVLVTGPSGAGRTTAINALEDMGYEVIDNLPLSFVPRLIEGPSIGRPIALGLDVRNRDFNATALIELIDRLTQDPRVALEVLYVDCSASELIRRYNQTRRRHPLAPAETPAEGVEREIDLLAPVRVRADHLIDTSEMSPHDLKAELSRWFDRGAATRLAVSVQSFSYKRGVPRGVDMIFDCRFLKNPYWVESLRALDGREASVADYISSDPRFAPFFEKLRDLVLFLLPAQLEEGKAHLSLGFGCTGGQHRSVAVAELLGNALAEAGWPVSKRHRELERRAAAVLPTHQGEKA
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein RHOS4_02640.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: IPYR_MALP2
Sequence: MKLNVTIEIPKKSNVKYEYDRKTNQISVDRILFGTEVYPHNYGFIKEALDWDGDELDALVIADQSFLPGIIVPAKIIGAMEMIDDGETDTKLISVIDCDPRYKHINNLSDLGEHTLKEIQNFFETYKLLQNKKVVIKGFKDSAWATKEYNECVELMKKYGKMDKDEFVNKMKKEHPEKYKA
What is the function of this protein?
Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
What are the official names of this protein?
Inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCA32_ARATH
Sequence: MTEQEICVRVTRAAAKRKASTAMGIDGDRVNKKRVVLGELLNVSNVNLLANLNQKKETQKPKRNLKPPPAKQIKSAPVAIIDLESKSDIDSRSDDPQMCGPYVADIYEYLRQLEVKPKQRPLPDYIEKVQKDVTPSMRGVLVDWLVEVAEEYKLGSETLYLTVSHIDRFLSLKTVNKQKLQLVGVSAMLIASKYEEISPPKVDDFCYITDNTFSKQDVVKMEADILLALQFELGRPTINTFMRRFTRVAQDDFKVPHLQLEPLCCYLSELSILDYKTVKFVPSLLAASAVFLARFIIRPKQHPWNQMLEEYTKYKAADLQVCVGIIHDLYLSRRGGALQAVREKYKHHKFQCVATMPVSPELPVTFWEDVTI
What are the official names of this protein?
Cyclin-A3-2, G2/mitotic-specific cyclin-A3-2, CycA3;2.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
Protein: RIBF_ECOLI
Sequence: MKLIRGIHNLSQAPQEGCVLTIGNFDGVHRGHRALLQGLQEEGRKRNLPVMVMLFEPQPLELFATDKAPARLTRLREKLRYLAECGVDYVLCVRFDRRFAALTAQNFISDLLVKHLRVKFLAVGDDFRFGAGREGDFLLLQKAGMEYGFDITSTQTFCEGGVRISSTAVRQALADDNLALAESLLGHPFAISGRVVHGDELGRTIGFPTANVPLRRQVSPVKGVYAVEVLGLGEKPLPGVANIGTRPTVAGIRQQLEVHLLDVAMDLYGRHIQVVLRKKIRNEQRFASLDELKAQIARDELTAREFFGLTKPA
What is the function of this protein?
Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.
What are the official names of this protein?
Bifunctional riboflavin kinase/FMN adenylyltransferase, Riboflavin biosynthesis protein RibF.
What is the protein family that this protein belongs to?
Belongs to the RibF family.
Protein: RL21_PROA2
Sequence: MQALIEISDKQYLVQPGDELFIPRQQAEVGDVLDIKPMVAIDQENTTLQPSGNVQVKVLEHLKGEKVVVFKKKRRKRYQCRNGHRQQMTKVEVLSM
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: NODU_RHIFR
Sequence: MKTACFPVFRNRLPDLDRDLDRDTKRVCGIKLTHDGAIAVVEDGRLVFCTEQEKRNNNSRYQEINNLDAVVAALAENGVNARDVDQFVIDGWDGEAESRFKVLSGETPVILRGAPYVERHAEGLLDWIGGSGLTLGDRVFSYRSYPHVTSHVASAYCTSPFAKSGDPALCLVWDGCIFPQLYHVEGKRASFVKSLFPVTGQAYAAAGHYFGPYKQTSRGGWDLGVAGKLMAFVALGSVHVRIVAVFQKLYQEHFAGDTALACAFRANINNSESSLAAVHDFFAASALQLGQRRPKTCLHRLIFSSNVSSLTKWRTLQHHPLPGARNLCIAGGCGLNIKWNSALRQTGLFDSVWVPPFPNDSGSAIGAACCEIVAQQGFVPLDWSVYSGPSLQDRQVPAGWHASPCSISEVAAILASNKPVVFLSGRTELGPRALGGRSILAAATSPEMKDHLNEIKFREHFRPVAPICLEDRAPDIFSPGTPDPYMLFDHQTKMPWQDKVPAVVHLDGSARLQTISRNSQHKVAEVLVEYEKLTGIPLLCNTSANYHGRGFFPSAAAACEWGRVEHVWCDGMLYRKPSATA
What is the function of this protein?
Involved in 6-O-carbamoylation of Nod-factors.
What are the official names of this protein?
Nodulation protein U.
What is the protein family that this protein belongs to?
Belongs to the NodU/CmcH family.
Protein: GPTC4_BOVIN
Sequence: MSITPEVKSRGMKFAEEQLLKHGWTQGKGLGRKENGITQALRVTLKQDTYGVGHDPAKEFTNHWWNDLFNKTAANLVVETRQDGVQIRRLSKETTRQDHAKPNLLYQKFVKTATLTSSGEKPDKDWESCSDDDSQEPKPPNVLTDEMLLQACEGRTAHKAARLGITMKAKLARLEAQEQAFLAQLKGQDPGVPQLQSESKSPKKKKKKRKQKEEEEPTTTERSAEKYSEHTDESIRKSKKKKRQHQEERVTDEREGTAIENEEETIRTGGLGELKNREHVDRSFRKKKRRGQHHEERAELAVLDNEGGKVAVSEVGTEEAERRVYTHPCGRSKKRRQHEEEDLNTEDEEVEEALVDSGTREAESRSCSDQKRGRSKKKRRQYQEEEVLDGPGVNTAQKAKKKKQKKRD
What are the official names of this protein?
G patch domain-containing protein 4.
Protein: PYRE_LEPBP
Sequence: MSHSHRDALFQWMKTYVYRHSETPFRLASGLESQHYFNCKEITLHPERLSILAECFIEEIIPKLNIEFQAVGGLTLGADPIAYAISLGYQKRGKNVFPLVVRKESKGHGTGQQIEGFWKDIKTCLVVDDVITTGGSTLKAVKVLREVGINVTKGICILDREEGGSENLQTENVTMTSIFAKSEFF
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: MO4L1_RAT
Sequence: MAPKQDPKPKFQEGERVLCFHGPLLYEAKCVKVAIKDKQVKYFIHYSGWNKNWDEWVPESRVLKYVDANLQKQRELQKANQEQYAEGKMRGAAPGKKTSGLQQKNVEVKTKKNKQKTPGNGDGGSTSETPQPPRKKRARVDPTVENEETFMNRVEVKVKIPEELKPWLVDDWDLITRQKQLFYLPAKKNVDSILEDYANYKKSRGNTDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEILADHPDAPMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLNYLHDFLKYLAKNSATLFSASDYEVAPPEYHRKAV
What is the function of this protein?
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A.  This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription.  This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair.  The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400.  NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage.  Also a component of the mSin3A complex which acts to repress transcription by deacetylation of nucleosomal histones.  Required for homologous recombination repair (HRR) and resistance to mitomycin C (MMC).  Involved in the localization of PALB2, BRCA2 and RAD51, but not BRCA1, to DNA-damage foci (By similarity).
What are the official names of this protein?
Mortality factor 4-like protein 1, MORF-related gene 15 protein, Transcription factor-like protein MRG15.
What are the subcellular locations of this protein?
Nucleus.