PharMolix/UniProtQA huggingface dataset:
Protein: RS12_LISMC
Sequence: MPTINQLVRKPRQSKIKKSTSPALNKGLNSFKRELTDVNSPQKRGVCTRVGTMTPKKPNSALRKYARVRLSNGIEVTAYIPGIGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGALDTAGVENRGQSRSKYGTKKPKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: FUCI_SALHS
Sequence: MKKISLPKIGIRPVIDGRRMGVRESLEEQTMNMAKATAVLITEKIRHACGAQVECVIADTCIAGMAESAACEEKFSSQNVGVTITVTPCWCYGSETIDMDPMRPKAIWGFNGTERPGAVYLAAALAAHSQKGIPAFSIYGHDVQDADDTSIPADVEEKLLRFARAGLAVASMKGKSYLSVGGVSMGIAGSIVDHNFFESWLGMKVQAVDMTELRRRIDQKIYDEAELEMALAWADKNFRYGEDQNASQYKRNEAQNRAVLKESLLMAMCIRDMMQGNKTLAGKGLVEESLGYNAIAAGFQGQRHWTDQYPNGDTAEALLNSSFDWNGVREPFVVATENDSLNGVAMLFGHQLTGTAQIFADVRTYWSPEAVERVTGQALSGLAEHGIIHLINSGSAALDGACKQRDSEGKPTMKPHWEISQQEADACLAATEWCPAIHEYFRGGGYSSRFLTEGGVPFTMTRVNIIKGLGPVLQIAEGWSVELPKAMHDQLDARTNSTWPTTWFAPRLTGKGPFTDVYSVMANWGANHGVLTIGHVGADFITLAAMLRIPVCMHNVEEAKIYRPSAWAAHGMDIEGQDYRACQNYGPLYKR
What is the function of this protein?
Converts the aldose L-fucose into the corresponding ketose L-fuculose.
What are the official names of this protein?
L-fucose isomerase, 6-deoxy-L-galactose isomerase, FucIase.
What is the protein family that this protein belongs to?
Belongs to the L-fucose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARK72_RAT
Sequence: MLRAVSRAVSRAAVRCAWRSGPSVARPLAMSRSPAPRAVSGAPLRPGTVLGTMEMGRRMDASASAATVRAFLERGLNELDTAFMYCDGQSESILGSLGLGLGSGDCTVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPRVDLFYLHAPDHGTPIVETLQACQQLHQEGKFVELGLSNYASWEVAEIYTLCKSNGWILPTVYQGMYNATTRQVETELLPCLRYFGLRFYAYNPLAGGLLTGKYRYEDKDGKQPEGRFFGNSWSETYRNRFWKEHHFEAIALVEKALKTTYGTSAPSMTSAALRWMYHHSQLQGTRGDAVILGMSSLEQLEQNLAATEEGPLEPAVVEAFNQAWNVVAHECPNYFR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate.  May have an important role in producing the neuromodulator gamma-hydroxybutyrate (GHB).  Has broad substrate specificity.  Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol.  Acts as a 2-carboxybenzaldehyde reductase.
What are the official names of this protein?
Aflatoxin B1 aldehyde reductase member 2, rAFAR2, Succinic semialdehyde reductase, SSA reductase.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack. Cytoplasm. Note=Its association with the Golgi stack may facilitate secretion of GHB.
Protein: DPO3_STAAC
Sequence: MAMTEQQKFKVLADQIKISNQLDAEILNSGELTRIDVSNKNRTWEFHITLPQFLAHEDYLLFINAIEQEFKDIANVTCRFTVTNGTNQDEHAIKYFGHCIDQTALSPKVKGQLKQKKLIMSGKVLKVMVSNDIERNHFDKACNGSLIKAFRNCGFDIDKIIFETNDNDQEQNLASLEAHIQEEDEQSARLATEKLEKMKAEKAKQQDNNESAVDKCQIGKPIQIENIKPIESIIEEEFKVAIEGVIFDINLKELKSGRHIVEIKVTDYTDSLVLKMFTRKNKDDLEHFKALSVGKWVRAQGRIEEDTFIRDLVMMMSDIEEIKKATKKDKAEEKRVEFHLHTAMSQMDGIPNIGAYVKQAADWGHPAIAVTDHNVVQAFPDAHAAAEKHGIKMIYGMEGMLVDDGVPIAYKPQDVVLKDATYVVFDVETTGLSNQYDKIIELAAVKVHNGEIIDKFERFSNPHERLSETIINLTHITDDMLVDAPEIEEVLTEFKEWVGDAIFVAHNASFDMGFIDTGYERLGFGPSTNGVIDTLELSRTINTEYGKHGLNFLAKKYGVELTQHHRAIYDTEATAYIFIKMVQQMKELGVLNHNEINKKLSNEDAYKRARPSHVTLIVQNQQGLKNLFKIVSASLVKYFYRTPRIPRSLLDEYREGLLVGTACDEGELFTAVMQKDQSQVEKIAKYYDFIEIQPPALYQDLIDRELIRDTETLHEIYQRLIHAGDTAGIPVIATGNAHYLFEHDGIARKILIASQPGNPLNRSTLPEAHFRTTDEMLNEFHFLGEEKAHEIVVKNTNELADRIERVVPIKDELYTPRMEGANEEIRELSYANARKLYGEDLPQIVIDRLEKELKSIIGNGFAVIYLISQRLVKKSLDDGYLVGSRGSVGSSFVATMTEITEVNPLPPHYICPNCKTSEFFNDGSVGSGFDLPDKTCETCGAPLIKEGQDIPFETFLGFKGDKVPDIDLNFSGEYQPNAHNYTKVLFGEDKVFRAGTIGTVAEKTAFGYVKGYLNDQGIHKRGAEIDRLVKGCTGVKRTTGQHPGGIIVVPDYMDIYDFTPIQYPADDQNSAWMTTHFDFHSIHDNVLKLDILGHDDPTMIRMLQDLSGIDPKTIPVDDKEVMQIFSTPESLGVTEDEILCKTGTFGVPEFGTGFVRQMLEDTKPTTFSELVQISGLSHGTDVWLGNAQELIKTGICDLSSVIGCRDDIMVYLMYAGLEPSMAFKIMESVRKGKGLTEEMIETMKENEVPDWYLDSCLKIKYMFPKAHAAAYVLMAVRIAYFKVHHPLYYYASYFTIRASDFDLITMIKDKTSIRNTVKDMYSRYMDLGKKEKDVLTVLEIMNEMAHRGYRMQPISLEKSQAFEFIIEGDTLIPPFISVPGLGENVAKRIVEARDDGPFLSKEDLNKKAGLSQKIIEYLDELGSLPNLPDKAQLSIFDM
What is the function of this protein?
Required for replicative DNA synthesis.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.
What are the official names of this protein?
DNA polymerase III PolC-type, PolIII.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. PolC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRM6_ASHGO
Sequence: MDPLRQLVLNQHILVRLPSDNLKIVELKPNGVISLGKFGACHVNDIIGYPLGTTFEIWYEGDETEVVRGSTVVIGKVRVLENRAEAQVGSEGATPQPAELTQVESSKTNMELLDLGHKVQKLDHKEIERMKQDVTAGDSIISMMIQSHETFHKKTIHSQEKYLKRKKQKFAKFFTAEYLGSSGLLRYLIEKGDMQRIMDLSEESLGMALNLANIRSNGTYLCMDETGGLIVYAMLERMFGGHEAQHGGTIVVVHENEHPNLDLLKFSNYSEEFIGKHVKTVSLLQYFEPPTVEEVEASFTPLDDAQLREMKSNKKGAYYRRLKRYNSDLEVIRLASQITYDALIVASTLQLSTLVPRLAGKVHGSRPIVCYSQFRETLLELSHTLYDSLHFLAPTLLETRCRPYQTVRGKLHPLMTMRGGGGYLLWCHKVIPADNGAGKIDCDNAAAPACPAAQPDEAP
What is the function of this protein?
Substrate-binding subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
What are the official names of this protein?
tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6, tRNA(m1A58)-methyltransferase subunit TRM6, tRNA(m1A58)MTase subunit TRM6.
What is the protein family that this protein belongs to?
Belongs to the TRM6/GCD10 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: XPT_MOOTA
Sequence: MVALSVVELLKEKIRQEGRVISDDVLKVDSFLNHQIDPVLMLKVGEEFARRFAGSAITKVLTVEASGIAVALMTGLSLKVPVVFAKKKQPSTMDGETYCGRVRSFTKEEVIDIVVAGSYLGPEDRVLIIDDFLASGEAARGLLKIITQAGATLVGVGTVIEKVFQTGGEALRDQGIRVESLVQIGSLAGGQIEFLN
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_BURM9
Sequence: MARVCQVTGKAPMSGNNVSHANNKTKRRFLPNLQNRRFWVESENRWVRLRVSNAGLRLIDKNGIDSVLADLRARGEA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: XGAT3_POPTR
Sequence: MNRFFYTVGLIFLFSFFILYSPKTSDLSNNVDLHQQLLISLQKEEERCDLFSGYWVQDLRGSQYTNVSCSSIPESKNCFMQGRPDAGFSQWRWKPDGCELPRFDPGTFFEIVRGKTMAFIGDSVARNHVESLLCLLSSEEMPLGIYKDTEDRTRTWYFPHSNFTLMVIWTRFLVLDEERVINGSVTGVFDLHLDKMDKNWANKLPEIDYAILSDAHWFFRKNYLYEKGKNIGCIFCGEPGIKSLDIDSALQMVIKVVLNYINNCKKCRNILTVLRTFSPAHFADGAWDTGGSCNRTHPLGEKEIDLASLDWKIRSIQVEEIKRVRPVARRRKKFEVLDVTKAMLMRPDGHPNSYWGNKWMKGYNDCVHWCMPGPIDAWNDFLIALLRRHAFTDFTWS
What is the function of this protein?
Xyloglucan acetyltransferase that catalyzes the acetylation of fucosylated Gal residues on xyloglucan side chains (PubMed:30083810).  Predominantly catalyze 6-O-monoacetylation of Gal residues in the Fuc-Gal-Xyl trisaccharide side chains of xyloglucan oligomers (PubMed:30083810).
What are the official names of this protein?
Xyloglucan O-acetyltransferase 3, PtrXGOAT3.
What is the protein family that this protein belongs to?
Belongs to the PC-esterase family. TBL subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: PTH_SCHPO
Sequence: MAIKHLPKILIARKNKAEVNHCDLKRRVSIKIIYGLGNPGSAFVKSRHSLGKLMVSMYADSMAFPKNWPSTKENLTLVLSTSYMNDSGKQLKKISNDFVRKVSPLDKIVYVVVHDELELDLGKVKLRLPGGSHRGHNGIRSCQEFLGKESFYRIGLGIGRCESRNREDVSDYVLSKFNSNEMKLIETDIFHKFCNILQQLQLSIET
What are the official names of this protein?
Probable peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: FOLD_CHLAD
Sequence: MSARILDGRVLAQALRHELAAQIAELRERIDRAPVIAVVQVGEDPAATRYVRSIDRLSQSLGAACRTIILPDVVTQAELEATVSRLSADDRVDGILLQLPLPAGLSLDGVLSRLIPEKDLDGIHPINAGLLAQGRPALIPNTPAGGMELLRRYEIEVRGKRAAVVGRSAIVGRPMALLLLQADATVTICHSRTSDLGAVLRECDIIVAAAGRPQLITAEMIKPGATIIDFGTNVLADGSMVGDVDFAAAVEVAGAITPVPGGTGPVTNVMLIQNLIKATRSRLGI
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: RSMA_XANOM
Sequence: MNSSFSAPAKKSLGQHFLADRYYIDRIVQAVDPRAGQHLVEIGPGQGAITFPLLRKHGALTVIEFDRDLIAPLTEAAAPIGALSIIHRDVLSVDFTALADGTPIRLVGNLPYNISSPILFHALDHAAVVADMHFMLQKEVVDRMAAGPGSKVYGRLSVMLQAYCDVTALFVVPPGAFRPPPKVDSAVVRLVPRDPATVHINDRRRFADVVRAGFGQRRKTLRNALSTVCEPAHFEAAQVRPDARAEQLEVADFIRLANVEPA
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CASP6_BOVIN
Sequence: MSSEPPPRRARGPGEEQNMTEIDAFPRREIFDPTEKYKMDHKRRGIALIFNHERFFWHLTLPNRPGTSADRDNLRRRFSDLGFEVKCFDDLRAEELLLKIHEASTASHVDADCFLCVFLSHGEGNHIYAYDAKIEIQTLTGLFKGDKCQSLVGKPKIFIIQACRGSQHDVPVIPLDVVDHRTDTPDANLTQVDAASVYTLPAGADFLMCYSVAEGYYSHRETVNGSWYIQDLCEMLGKFGSSLEFTELLTLVNRKVSQRRVDFCRDPNAIGKKQVPCFASMLTKKLHFSPKSK
What is the function of this protein?
Cysteine protease that plays essential roles in programmed cell death, axonal degeneration, development and innate immunity (By similarity).  Acts as a non-canonical executioner caspase during apoptosis: localizes in the nucleus and cleaves the nuclear structural protein NUMA1 and lamin A/LMNA thereby inducing nuclear shrinkage and fragmentation.  Lamin-A/LMNA cleavage is required for chromatin condensation and nuclear disassembly during apoptotic execution (By similarity).  Acts as a regulator of liver damage by promoting hepatocyte apoptosis: in absence of phosphorylation by AMP-activated protein kinase (AMPK), catalyzes cleavage of BID, leading to cytochrome c release, thereby participating in nonalcoholic steatohepatitis.  Cleaves PARK7/DJ-1 in cells undergoing apoptosis (By similarity).  Involved in intrinsic apoptosis by mediating cleavage of RIPK1.  Furthermore, cleaves many transcription factors such as NF-kappa-B and cAMP response element-binding protein/CREBBP (By similarity).  Cleaves phospholipid scramblase proteins XKR4 and XKR9.  In addition to apoptosis, involved in different forms of programmed cell death.  Plays an essential role in defense against viruses by acting as a central mediator of the ZBP1-mediated pyroptosis, apoptosis, and necroptosis (PANoptosis), independently of its cysteine protease activity.  PANoptosis is a unique inflammatory programmed cell death, which provides a molecular scaffold that allows the interactions and activation of machinery required for inflammasome/pyroptosis, apoptosis and necroptosis.  Mechanistically, interacts with RIPK3 and enhances the interaction between RIPK3 and ZBP1, leading to ZBP1-mediated inflammasome activation and cell death.  Plays an essential role in axon degeneration during axon pruning which is the remodeling of axons during neurogenesis but not apoptosis.  Regulates B-cell programs both during early development and after antigen stimulation (By similarity).
What are the official names of this protein?
Caspase-6, CASP-6.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: B1R1_LOXSN
Sequence: FALAQMVNDLEMVDEFVGKGANGLEIDVTFSSSGQPQYTYHGVPCDCFRSCKRREDFDTYIKYIRHLTTPGDPKFRSNLIMLIFDLKLNGLSQDALRKAGVEMADKLVGNYWQDLAEARAYIVLSMPSIEQSAFVTAFKDELKDFGYDKNLDRIGYDFSGNEDLDETAKVYKQLNINGHIWQADGITNRLPRGDSRLKEAISKRDTPGYQYINKVYTWTIDKASSIANALRLGVDGVMTNYPERVIDALNDSEFSGKFRLATYEDNPWETFKG
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LspiSicTox-betaIE1i, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class I subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: EX7L_SHIBS
Sequence: MLPSQSPAIFTVSRLNQTVRLLLEHEMGQVWISGEISNFTQPASGHWYFTLKDDTAQVRCAMFRNSNRRVTFRPQHGQQVLVRANITLYEPRGDYQIIVESMQPAGEGLLQQKYEQLKAKLQAECLFDQQYKKPLPSPAHCVGVITSKTGAALHDILHVLKRRDPSLPVIIYPTSVQGDDAPGQIVRAIELANQRNECDVLIVGRGGGSLEDLWSFNDERVARAIFASRIPVVSAVGHETDVTIADFVADLRAPTPSAAAEVVSRNQQELLRQVQSTRQRLEMAMDYYLANRTRRFTQIHHRLQQQHPQLRLARQQTMLERLQKRMSFALENQLKRTGQQQQRLTQRLNQQNPQPKIHRAQTRIQQLEYRLAETLRVQLSATRERFGNAVTHLEAVSPLSTLARGYSVTTATDGNVLKKVKQVKAGEMLTTRLEDGWIESEVKNIQPVKKSRKKVH
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BP11B_CROVV
Sequence: QGGAPWNPIPP
What is the function of this protein?
This peptide both inhibits the activity of the angiotensin-converting enzyme (ACE) and enhances the action of bradykinin by inhibiting the peptidases that inactivate it.  It acts as an indirect hypotensive agent (By similarity).
What are the official names of this protein?
Bradykinin-potentiating peptide 11b, BPP-11b.
What is the protein family that this protein belongs to?
Belongs to the bradykinin-potentiating peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: NAGB_SHESH
Sequence: MQIVILKDSAEVAAYGANIFIKQLQKKTNSVLGLATGSTPVSLYRGLIEACDAELISFKDVTSFNLDEYLGLKGTHPQSYRYFMNEQLFNHIDIIKAQTYVPPGDAENPLEACVGYEEKIKAAGGIDIQLLGIGRNGHIGFNEPSSGLMSRTRVKTLTKATIEDNARFFHDDEYQPHLSITMGIGTILDAKKVVLLATGENKADAILATVEGPLMAACPASALQLHTDAVLVIDEAAASKLSDRDFYKHIENENQKLMAKLP
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: ALR_SYMTH
Sequence: MDLDGMRPTWAEVDLNAVRANIRALKRISKAPRLMAVVKANGYGHGAVPVATAAIEAGADWLGVASVEEGVTLRRHGISAPILVLGYVSPGQAEAVLTEGLRVALFDGELGQALNREGRRLGRWARVHLKVDTGMGRIGLQPAEVGRLGRELARLDHVEVEGVFTHLATADEPGNPYTRLQLERYEAALAELAAAGVRPAIRHAANSAGLMLHPEAHYDMVRSGIAVVGLPPAPGVAWPVKLAPALTWKTRVGLVKWLEAGHSISYGCTYTTARREQIATLPVGYADGYPRRLSNRAQVLIRGRRCPVVGVVTMDQMMVRVPDDLPVRVGDEVVLIGRQGGEEITATELAGLADTISYEIVCGISRRVPRFYGGETA
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: DNLJ_CITBB
Sequence: MDKTAAAQRIKWLSSEIERHNRLYYEQDMPEITDAEYDALFRELKELEASYPDLALPDSPTGRVGGRPVAKFTQVRHTTPMLSLENAFTEKDIVDFDDRMKRFLGLSGAEEIGYVCEPKMDGVAVELVYRDGLLAIGSTRGDGLVGEEVTQNLKTIKDIPLRLQTEEPPGLLTVRGEVYLPLEPFRKFNQEREEAGEPPFANPRNAAAGSLRQLDSKITAKRPLSIFCYAPGEVDGVAFQSQSDFLSTIPTWRIPVNPLTRLVPGVQGVLDYYNEMMEKRDDLPYEIDGVVVKVDRFSLQRDLGEKSRSPRWAIAWKFPPRQATTVVNDIVPQVGRTGVITPVAHLEPVNVSGVMVSRATLHNWEEMERKDIRRGDTVVVERAGDVIPAVVQVLVEKRQGSETLLPVPQACPVCGGEVVRIPGEVAVRCVGLNCPAQALERVKHFAARRAMDIDGLGEKFIEQLLNLKLIRNVADIYRLTEEDFMQFERMGKKLAENLLNSIAASKERELSRLIFALGIRHVGEHTAKLLASAFGSMENLAAASEEELTSIREVGPQVAASIADFFKSEENLEVLRELKEHGVNPRVEEKRVGGRFTGKTFVFTGALEKFTRDEAKKMVELEGGHAAGSVSKKTDYVVAGADAGSKLDKAQQLGVRVLSEDDFLELMQ
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: SUS2_DAUCA
Sequence: MAQPLLSLRQRFESTFSSHRQEIFMFLSRIQSLGNGILKPHQLFSEFQAISKIDRLKLEDSALVQLLNSAQEAIVCSPWIALAIRLRPGVWEYVRLNVHQLVVEELTVPDYLYLKEELVNASSNGNFVLELDFAPFTASIPRPTLTKSIGNGVEFLNRHLSAKMFQDKDSMHPLLDFLRLHHHNGRTLMLNNRVQTVNGLQDILRIAGEYLSKLPSDTPYSDFEHKFQEIGFERGWGDTAEHVSEMFHMLLDLLEAPDACTLETFLGKIPMIFNVVILSPHGYFAQENVLGYPDTGGQVVYILDQVPAMEREMTKRIKEQGLDIIPRILIVTRLLPDAVGTTCNLRLEKVFGAEHSHILRVPFRTEKGILRKWISRFEVWPYMETFTEDVAKEIALELKAKPDLIIGNYSEGNLVASLLANKLGVTQCTIAHALEKTKYPDSDIYWEKFDKKYHFSSQFTADLIAMNHTDFIITSTFQEIAGSKDTVGQYESHTAFTMPGLYRVVHGIDVFDPKFNIVSPGADTSVYYPYTEKKRRLTALHPEIEDLLFSSVENKEHICVLKDRYKPILFTMARLDNVKNLTGIVEWYAKNPKLRELVNLVVVGGDRRKESKDLEEQAQMKKMYGLIDTYKLNGQFRWISAQKNRVRNGELYRCIADTKGAFVQPAFYEAFGLTVIEAMTCGLPTFATIHGGPAEIIVHGTSGFHIDPYHGEKAAELIVNFFERCKTEPSHWETISAGGLKRIQEKYTWQIYSERLLTLGGVYGFWKHVSKLDRIEIRRYLEMFCALKYRNLAESVPLAVD
What is the function of this protein?
Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways.
What are the official names of this protein?
Sucrose synthase isoform 2, Sucrose synthase isoform II, Sucrose-UDP glucosyltransferase 2, Susy*Dc2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Plant sucrose synthase subfamily.
Protein: URE1_STAA9
Sequence: MSFKMTQNQYTSLYGPTVGDSIRLGDTNLFAQIEKDYAVYGEEATFGGGKSIRDGMAQNPRVTRDDVNVADLVISNAVIIDYDKVVKADIGIKNGYIFAIGNAGNPDIMDNVDIIIGSTTDIIAAEGKIVTAGGIDTHVHFINPEQAEVALESGITTHIGGGTGASEGSKATTVTPGPWHIHRMLEAAEGLPINVGFTGKGQATNPTALIEQINAGAIGLKVHEDWGATPSALSHALDVADEFDVQIALHADTLNEAGFMEDTMAAVKDRVLHMYHTEGAGGGHAPDLIKSAAFSNILPSSTNPTLPYTHNTVDEHLDMVMITHHLNAAIPEDIAFADSRIRKETIAAEDVLQDMGVFSMISSDSQAMGRVGEVITRTWQVAHRMKEQRGPLDGDFEHNDNNRIKRYIAKYTINPAITHGISEYVGSIEPGKLADIVLWDPIFFGVKPELVVKGGLINSAVNGDANGSIPTSEPMKYRKMYGQYGGNLTSTSMTFVSKTAYENGINRALNLKRMVRPVKNIRQLSKADMKNNSATPKLDVDPQTYEVYVDGENITSNAATELPLTQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBAR2_MOUSE
Sequence: MNVVLSRDSQVRAMENTVTNAERYFGQFCSLLASYTRKTARLRDKADQLVKQLIDFANTENPELRATIRDFAEDLAKVQDYRQAEVERLEAKVISPLKLYGAQIKQTRADIKKCKRVQNNEIKQLEKLEKLRQKSPSDRQMISQAETSAQRASVDTNRSTLHLVETVDAFQEQKLKDLRRIFSDFVTIEMVFHAKAVEVYSSAFQTLENYDLERDLQDFRAKTRGIYGHGEARPLTDTNPAPSVPWPLASQSAQSTMARQGKEAGGEEDSETDSVEEIPLEDLKGQQQGPRD
What is the function of this protein?
May play a role in ciliogenesis.  In cooperation with CBY1 may facilitate ciliogenesis likely by the recruitment and fusion of endosomal vesicles at distal appendages during early stages of ciliogenesis.
What are the official names of this protein?
CBY1-interacting BAR domain-containing protein 2, Protein FAM92B.
What is the protein family that this protein belongs to?
Belongs to the CIBAR family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body. Note=Extensive colocalization with CBY1 at mother centrioles (PubMed:27528616).
Protein: Y1257_PSEA7
Sequence: MSEATAATVALGKSWSVYLVRAANGALYCGISDDPLRRFDTHCSGKGARFFHSSPARALVYVEACASKGDALRRERAIKALSKRAKERLLVGVPVLREVGEPAI
What are the official names of this protein?
UPF0213 protein PSPA7_1257.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: SYS_NEIM0
Sequence: MLDIQLLRSNTAAVAERLAARGYEFDAARFNALEEQRKAVQVKTEELQASRNSISKQIGALKGQGKHEEAQAAMDQVAQIKTDLEQAAADLDAVQKELDAWLLSIPNLPHESVPAGKDETENVEVRKVGTPREFDFEIKDHVDLGEPLGLDFEGGAKLSGARFTVMRGQIARLHRALAQFMLDTHTLQHGYTEHYTPYIVDDTTLQGTGQLPKFAEDLFHVTRGGDETKTTQYLIPTAEVTLTNTVADSIIPSEQLPLKLTAHSPCFRSEAGSYGKDTRGLIRQHQFDKVEMVQIVHPEKSYETLEEMVGHAENILKALELPYRVITLCTGDMGFGAAKTYDLEVWVPAQNTYREISSCSNCEDFQARRMKARFKDENGKNRLVHTLNGSGLAVGRTLVAVLENHQNADGSINIPAALQPYMGGVAKLEVK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBQ_THEVB
Sequence: MKAKSLMVVGTTSHAGKSLLAAVICRWLAQQGYRVTPFKGQNMALNAYVTREGGEIGYAQAMQAWAAGIEPEVAMNPILLKPQGNMTSQVILRGQVVGVTRAADYYRDYFERGWQAITEALADLQQRFDWIVCEGAGSPAEINLKHRDLTNMRVATYLGAPTILVADIDRGGVFAHIVGTLMLLEPAERALIQGIVINKFRGQRSLLDSGLQWLEETTGVPVLGVIPWLERHYAAEDSLDLWDPRPQRQGADLKITVIRLPRIANFTDIDPLLAEPSVAVEFLPPHRPLGRPDAVILPGTKTTIADLQVLRETGMAEQLKTYAAQGGTILGICGGWQMLGTAISDPLGLEGCPGTYEGLGLMPLHTQLGPTKCTQQQQTQSLYFNCPEPILGYEIHQGQSEYTGDRQGWHPLFAAPELGLVNRAGTLWGTYLHGLLENGPWRRHWLNGLRSRRQLPPLPTAIPHYGEQRTVALDELTKTVMAHLNLRGICKLC
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.