PharMolix/UniProtQA huggingface dataset:
Protein: PDED_PLAF7
Sequence: MNEYNNDNMEQEKEKKKEEQKYKNIIKKEYFIFPRLYDKNKEIEYNKLRIHNIKEYICIHLTISLFIILIECFVFSFNLNIKDTTYVEICVVIFSILNCLMHIVVLIKMYFFTSESVYTKGVFIGYIVLNQVFQFLSLYFFTKRNEQSKNDIAHLKYYDNSFNLYVHFFVDSVFILCLPALSFFLSVLFMMMFLCLNILLINMIKFNKTNYGSDIYHICLLSVVLLMFLILRYMMEERNRLLFFFIKDMMFDNYKKWYSDYIGAHYDKDKDSTTINGDNNKYEKEKCEDYKFLFSNKCILFHDFTLNACYKDYYSMICFLNKLLKSCNIKEDMSSNTSVNINGDTYQNMNFHDNINSNIPKNYNSFYEELKKNLNESDILTIAYEVEVLKNIKKINCDEIGKNWDYSFIDSEYGKSTLVILEVGYHLISPYIENNENKKKKLQLFLLLINSMYFPNPYHNANHGATVCHLSKCLAHITDYDSYLNNTYMICYLIASIAHDVGHPGKTNSYLSETNHILSIRYNDMSILENYHCSITFSILQLIGFDFLINNEDTKLVEKNNYTNMRKFIIELIISTDMKLHFEYVDIFKKRKKSQNFDISDTDAINLGTINIKLADIGHTCLKWKDHAKWTMLVSEEFFSQKRVEELHKNKNIDPLNFSNFGKEDNIDEGMIFNYENIYINYINNINNINTYDYSYIKLNFIHHHDFVKSIPSTQVYFFEIIVMPLIKELQSMEKSKKEITQKVLHNLNINLQTWRLIEKNINLFYNTEKMTGTDYYKNLEKQKLLRGIRLLDIAEEDVISLTKNFKEEIKHGKL
What is the function of this protein?
Specifically hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes (PubMed:18452584).  Probably by regulating cGMP levels, required for activation of gametogenesis (PubMed:18452584).
What are the official names of this protein?
cGMP-specific 3',5'-cyclic phosphodiesterase delta, PfPDEdelta.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MSHA_PAEAT
Sequence: MAFLSLHTSPMEQPGAGDAGGMNVYVRALAMALAESGVEVEIFTRSTKAGQPAVEHPGPGVCVHNVMAGPRRKLPKEELPELLHHMVEEIDRIRLQQLHGRYDAIHSHYWVSGVAGLELSELWGVPLVHTMHTMAKVKNLVLESGERPEPRRREEGEQRIVDGAARLVANTPAEADELVSHYGADLDRIDVAPPGVDLKVFTPSFRRKSRSLRGVRPDSFHILFAGRIQRLKGPQVFVKAAGILRKRRPDIDLEMTILGSLSGAKDFNLQHFIEDAGLADVVTHRPPVVAPELASWFRSADVVVMPSFSESFGLVALEAQACGTPVVATNVGGLSRAISDGRTGILVDGHHPSDWADALEDLYDDVQTREDMGRLAATHAESFGWQRTAAITLESYREAVSGLLVPRR
What is the function of this protein?
Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
What are the official names of this protein?
D-inositol 3-phosphate glycosyltransferase, N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase, GlcNAc-Ins-P N-acetylglucosaminyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. MshA subfamily.
Protein: YCF2_CUSEX
Sequence: MKKMMRHQVKLGILELREIMREIHNYYYLLLLDSWTKLNSVGSLIHLFFHQERFLKLFDPRIFSILLSRNLQGSPSNRYFTIKGVILFVVGVLIYRINNQNMVERKNLYLTGLFPIPMNSTGPIKDRLEEAIGSSNINRLSVLLLYFPKGKNISERYFLNPKETAGVLTITKKGSVPESNWGSRRWRNFIGVKRGNFSCPIANETVGGIDILFKDKFRKNMEFTFVYYMDDLTHNDPDWEFFYRLSTRKSENRINWNSGPLFKILVKDCISYLMSAFREKRPKGEGPESTIQSNKIRHVFHLFSIKRGTISLQNCTHFYMWQFRRDLFRSWGNNPPESSFLRNVSREISSNAWLGNKGRFFSKGRNVLSNLQYDSTGSSLVNVTDSSQLKGSEDQSIERLASIRNEDSEYHALINKREVQQLEESSMTLESDRLPKSLSGYCSTSQLFKERENPMINFMFPGEMEEFIGNPTRSVRSFCSDRWSELHLWSNPTEKSTLDHKFVKNHLSFVRGAENKEIKNLRRIITYLQKTVSIHSISSDPRWDRVPKHDPDMDSFKKNSLFFLFHRFHERNRGAYPLRHDFESEERLQEMTELFTLLISEPDLVYHKGFSFYIYIDSYGLDKKNLLNEVLNARAESKNKSLWVLSPILFRYEEIEYFFKRIRQKRVWWISCGNGLVDLKQNDDGYIRNLFNILFLMNKSDRNFEHRMQGDRKGTAIFNQRTIMKCMIKQDHTYIYKRSNGTKNFQEHLEHFLSQQKSDFKVQKRYFQVLFDQLRICLTKNLIHWFEVRKKVEKKVEKNVYKLVTFLLSKSLRFFFLPQSLHFFFIKVLRFVTEVILFLSNSFPSLCVSFGNTPIQRSEIYISELKSSNEQLCNKLFESIGFQIVHLKKLNPFLLEEFDTSNFVINVGTRSPFLLNKIPKRIFDSLPTRTNHSKYFDNKDSYFSKIFHDKDNWLNHPKPFHRSSLISSFYKANQLRFRNHLHHFLFYCNKRFPFSVEKARNTNSHFLYGQFLNILLFRKKIFSLCVGQKKHVFWSRATLSPIESQVSNIFIPKDFPQSGDEGYNLDKYFNFLIQPDPVIRRAISSIVETSGTPLTEAQKGDLERTYCKPLSDINLSDSEVNNFHEYPNFNSNMGLVHILFSGKYLSSEKHSLCLKKGAGVHKERMFTTFQRDSSFSILSETWNLFQTYLPSFFTSTGYKYLTSIFSENFSYLLSILSSRVSLFQDILGLSWRILQIRLSKMPLFLRREISSKWLHNLFLSKEMIRRKTQSSLISKHLRSTKFWEFFYSLLFLLLVAGYLVSIHFFFISRAFSELQTEFKSLKSLMTPSSAIELRKLLDKYPRSEPNSFWLKNIFLVVMEQLRDSLEEIKGFVFGLNRIGLTSGVKSIRFKNFKNKDFNIKGIGIIELILRPITRIAFSLNTRHISHTSKEIYSLIIKRKNVNGVWIDDKIESWVANSDSIHEEERKLLVQLSALTTEKRILLSLTHSDHFSKNDSGYQMIEQPGAIYLRYLVDIHQKHLMNYEFNTSCLAERRIFLAHSQTITYSQTSYGTNSFHFPSHGKPFSLRLALSPSRGILVIGSIGTGRSYLVKYLATNSYVPFITVFPNKFLDKNPQFIDDIDIDNSNNIDASDDIDMDNSDNIDDDIDRDLATELELLTWMNALTMDREMKAEIARLFITLQFELARAMSPCIIWIPNIHDLDVNESNYLSLGLLVNHLSRDCERCSPINILVIASTHIPQKVDPALIAPKKLNTCIKLRRLLIPQQRKYFFTLSYTRGFHLENKMFHTNGFGSITMGPNARDIVALTNEVLSISITQKKSIIDTNTIRSALHRQTWDLQSQVRLVQDHGILFYQIGRAVAQNVLLSNLSNCPIDPISIYLKKKSCNEGDSYLYKWYFELGTSMKKLTILLYLLSCTAGSVAQDLWSLPGPDEKNGITSYGLVENDSDLVHGLLEVEGALVGSSRTEKNCSKFENDRVTLLLRPEPRNPLERRQNGSCSILDQRFLSEKDESEFEEGALAPQQIEEDLFNHIVWAPTIWRPWGFLCIERPNELGFSYWSRSFRGKRILYDEEDELEENDSEFLQSGTMQYKTRDRSSKEKGLFRISQFIWDPADPLFFLFKDRPPGSVFSRLELFADEEMSKGLLTSQTSQIEHLFRYKYPRWFINKTQEKHFEFLIHRQRCLRTNSSLSNRSFRSNTLSESYQYLSNLFLSNGTLLDQMTKTLLRKRWLFPDEMKIGFM
What is the function of this protein?
Probable ATPase of unknown function.  Its presence in a non-photosynthetic plant (Epifagus virginiana) and experiments in tobacco indicate that it has an essential function which is probably not related to photosynthesis.
What are the official names of this protein?
Protein Ycf2.
What is the protein family that this protein belongs to?
Belongs to the Ycf2 family.
What are the subcellular locations of this protein?
Plastid.
Protein: RPO10_NANEQ
Sequence: MLPPIRCFSCGKPLGHLWEEFNERVNKGEDPKKVLDDLGLERYCCRRTLLSAVVVFPVIAKFKKV
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo10, DNA-directed RNA polymerase subunit N.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL33_CITBB
Sequence: MPRDIITLGCTECKQRNYTTTKNKKNTPQKLEFNKYCRFCQKHTLHKETK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: XPT_BACAN
Sequence: MKVLQEKILNEGKVLSGDVLKVDAFLNHQIDPVLMQEIGKEFAKRFKEENITKIVTIESSGIAPAVMAALELGVKVIFARKRKSLTLQDNMYVANVYSFTKQETNEISLSRNHIDESDRVLIIDDFLANGQAALGLMSLVEQAGASIAGIGIVIEKAFQDGGKKLREQGIRVESLAEIASLDNNAVTFVQQETAEVK
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOD_CYAP4
Sequence: MFTLLITGTDTDAGKTVLTTALAAYWRTYFPSQSVALLKPLQSGVGDRELYRELFALNQPPEEINPLYFQAPLAPPLAAELEQRSIDLSLPWQTLVKLRQSYDRVLVEGVGGLGSPITWELTVADLARDWGLATLLVVPVKLGAIGQAVANVALARQAGVNLKGIVLNCVQPRSETEIAQWAPADLITNLTQIPVLGVLPYLGDRTNLAQLAAAAAQLDLEAFLSA
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring (By similarity).  This cyanobacterium does not encode bioA (which catalyzes the formation of the precursor for this reaction in the cannonical pathway), instead it encodes bioU, which replaces bioA and also performs the first half of the cannonical BioD reaction.  Thus in this organism BioD has a different substrate (By similarity).
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIFB2_HAEIF
Sequence: MGKTMFKKTLLFFTALFFAALCAFSANADVIITGTRVIYPAGQKNVIVKLENNDDSAALVQAWIDNGNPNADPKYTKTPFVITPPVARVEAKSGQSLRITFTGSEPLPDDRESLFYFNLLDIPPKPDAAFLAKHGSFMQIAIRSRLKLFYRPAKLSMDSRDAMKKVVFKATPEGVLVDNQTPYYMNYIGLLHQNKPAKNVKMVAPFSQAVFEAKGVRSGDKLKWVLVNDYGADQEGEAIAQ
What is the function of this protein?
Mediates assembly of pili by forming soluble multimeric complexes with pili subunits as an intermediate step in the assembly process.  This protein is involved in type B pili (HifA) assembly.
What are the official names of this protein?
Chaperone protein HifB.
What is the protein family that this protein belongs to?
Belongs to the periplasmic pilus chaperone family.
What are the subcellular locations of this protein?
Periplasm.
Protein: ISPT_LEPIC
Sequence: MGLFESNLPKHIAVIMDGNGRWATSRGKSRSEGHREGAQAIDRLMDASLELGLKNISLYAFSTENWKRPVTEIRSIFSLLIEFIETRLDTIHKRGIRILHSGSRKKLTRGVLDKIDFAVDKTQKNKNLTVNFCLNYGSRDELLRAAQELFLERKRSKVALEKPLKEKEFEKFLYTSILPPVDLLIRTAGEQRLSNFLLWQSAYAELYFTDTLWPEFDKNSLVDSLKWYETRTRKFGGLTNG
What is the function of this protein?
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
What are the official names of this protein?
Isoprenyl transferase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: ALBU_MESAU
Sequence: MKWVTFLLLLFVSDSAFSRGLFRRDAHKSEIAHRFKDLGEQHFKGLVLIAFSQFLQKCPYEEHVKLVNEVTDFAKTCVADESAENCDKSLHTLFGDKLCAIPTLRDSYGELADCCAKKEPERNECFLKHKDDHPNLPPFVRPDAEAMCTSFQENAVTFMGHYLHEVARRHPYFYAPELLYYAEKYSAIMTECCGEADKAACITPKLDALKEKALASSVNQRLKCSSLQRFGQRAFKAWAVARMSQKFPKADFAEITKLATDLTKLTEECCHGDLLECADDRAELAKYMCENQASISSKLQACCDKPVLKKSHCLSEVENDDLPADLPSLAADFVEDKEVCKNYAEAKDVFLGTFLYEYARRHPDYSVALLLRLAKKYEATLEKCCAEADPSACYGKVLDEFQPLVEEPKNLVKANCELFEKLGEYGFQNALIVRYTQKAPQVSTPTLVEAARNLGKVGSKCCVLPEAQRLPCVEDYISAILNRVCVLHEKTPVSEQVTKCCTGSVVERRPCFSALPVDETYVPKEFKAETFTFHADICSLPEKEKQMKKQAALVELVKHKPKATGPQLRTVLGEFTAFLDKCCKAEDKEACFSEDGPKLVASSQAALA
What is the function of this protein?
Binds water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs.  Its main function is the regulation of the colloidal osmotic pressure of blood.  Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity).  Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity).  Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (By similarity).  The shared binding site between zinc and calcium at residue Asp-273 suggests a crosstalk between zinc and calcium transport in the blood (By similarity).  The rank order of affinity is zinc > calcium > magnesium (By similarity).  Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E. coli from ferric transferrin, and may thereby limit the utilization of iron and growth of enteric bacteria such as E. coli (By similarity).  Does not prevent iron uptake by the bacterial siderophore aerobactin (By similarity).
What are the official names of this protein?
Albumin.
What is the protein family that this protein belongs to?
Belongs to the ALB/AFP/VDB family.
What are the subcellular locations of this protein?
Secreted.
Protein: MALT_ECOBW
Sequence: MLIPSKLSRPVRLDHTVVRERLLAKLSGANNFRLALITSPAGYGKTTLISQWAAGKNDIGWYSLDEGDNQQERFASYLIAAVQQATNGHCAICETMAQKRQYASLTSLFAQLFIELAEWHSPLYLVIDDYHLITNPVIHESMRFFIRHQPENLTLVVLSRNLPQLGIANLRVRDQLLEIGSQQLAFTHQEAKQFFDCRLSSPIEAAESSRICDDVSGWATALQLIALSARQNTHSAHKSARRLAGINASHLSDYLVDEVLDNVDLATRHFLLKSAILRSMNDALITRVTGEENGQMRLEEIERQGLFLQRMDDTGEWFCYHPLFGNFLRQRCQWELAAELPEIHRAAAESWMAQGFPSEAIHHALAAGDALMLRDILLNHAWSLFNHSELSLLEESLKALPWDSLLENPQLVLLQAWLMQSQHRYGEVNTLLARAEHEIKDIREDTMHAEFNALRAQVAINDGNPDEAERLAKLALEELPPGWFYSRIVATSVLGEVLHCKGELTRSLALMQQTEQMARQHDVWHYALWSLIQQSEILFAQGFLQTAWETQEKAFQLINEQHLEQLPMHEFLVRIRAQLLWAWARLDEAEASARSGIEVLSSYQPQQQLQCLAMLIQCSLARGDLDNARSQLNRLENLLGNGKYHSDWISNANKVRVIYWQMTGDKAAAANWLRHTAKPEFANNHFLQGQWRNIARAQILLGEFEPAEIVLEELNENARSLRLMSDLNRNLLLLNQLYWQAGRKSDAQRVLLDALKLANRTGFISHFVIEGEAMAQQLRQLIQLNTLPELEQHRAQRILREINQHHRHKFAHFDENFVERLLNHPEVPELIRTSPLTQREWQVLGLIYSGYSNEQIAGELEVAATTIKTHIRNLYQKLGVAHRQDAVQHAQQLLKMMGYGV
What is the function of this protein?
Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides.  Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.
What are the official names of this protein?
HTH-type transcriptional regulator MalT, ATP-dependent transcriptional activator MalT.
What is the protein family that this protein belongs to?
Belongs to the MalT family.
Protein: CYB_PHOFA
Sequence: MTNIRKTHPLMKIINSSFIDLPAPSNISAWWNFGSLLGICLILQILTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWIIRYLHANGASMFFICLYMHVGRGLYYGSYTFTETWNIGIILLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVQWIWGGFSVDKATLTRFFAFHFILPFVVSALAAVHLLFLHETGSNNPSGIVSDSDKIPFHPYYTIKDILGALLLILVLMLLVLFSPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILAIVPLLHTSKQRGMMFRPISQCLFWLLVADLLTLTWIGGQPVEHPYITIGQLASILYFMILLVLMPIASIIENNILKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MURG_VIBPA
Sequence: MKQNKRLMVMAGGTGGHVFPGLAVAKQLQEQGWEIRWLGTADRMEADLVPKHGIEIDFIKVKGLRGQGVKRLLAAPFQIINAIMQARAHMKRWQPDAVLGMGGYVSGPGGIAAWLSGIPVVLHEQNAVAGLTNQWLSKIAKKVFQAFPGAFPSAAVVGNPVREDVTQLDEPAQRMQEREGPIRILVMGGSQGARILNQTLPAVMANLGQDYCIRHQAGKGAAQEVQAAYQANNVANAEVTEFIDDVAQAYAWADLLVCRSGALTVSEVSAAGVGAIFIPFMHKDRQQALNADHLVECGAAKMIEQPDLTVESLTQQIQQLDRQALLSMAQKARSAAKLDADKVVAQAIVALTEKR
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SYS_SULSY
Sequence: MIDIKLLRENPDFVKERLKTRDESYLKLIDRLLEIDEERRKIIKEIESLRAERNEKSKLFPILKKEGKDTTEIQQRVKQIGEIIKNLEDKLQEIENEFNNILYYIPNLPAPDVPIGKDENDNVEIRRWGKPRKFDFEPLSHYEIGERLGILDFERGAKLSGSRFTVMFKEAARLERALINFMLDVHTKQHGYTEVWTPALVKPEILFGTGQLPKFKDDLYKIEDEDLYLIPTAEVTLTNLHADEILNEEDLPKYYTAYTPCFRKEAGSHGKDVKGILRQHQFDKVELVKIVKPEDSYNELEKLVNEAEKILQLLEIPYRVVLLCTGDMGFSAAKTYDIEVWIPSQNRYREISSCSNTEDFQARRAKIRYKDKDGKNHYVHTLNGSGLAVGRTLIAIMENYQKPDGTFEIPKVLKDYL
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_PICTO
Sequence: MIRIGMVVAEFNYDITMMMLERARSYAEFLGVEVHKILRVPGSFDMPLAIKKLLMDNDIDGVVTIGAVIKGETDHHKIIMDNVSRKITDLSLEYNKPVALGISGPGESRLQAEARIDMAKEAVESCVKMIKLLKSN
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: ORB2_DROME
Sequence: MDSLKLPKANSATSSASGSNSNLSGSTSASASAATSPTSSGTAVGGILSGAPKSPPGLGSSTPISVRFNANEESLDDILQSFHHSKHSPSGGASGGGDASPTSNLLGMKNNGLGLVVGNCDSLSSSPSQPQMHAGSASLFGNDEVSLRNNFMQAGGFFNRKSCGGLPNLNLNKPPQLHQQQHQQQHQQHQQHQQQQQLHQHQQQLSPNLSALHHHHQQQQQLRESGGSHSPSSPGGGGGGSPYNGSQAGCSSGGISPIPPQMGVSPKYRRSISFPIKGNSPTAIYGNMHMDGMGSGHMNIPTLSIGNGGGGGSTGMVSAGATGGGDAPYLGNSYGNMMTSNGQMHHGGGLDNSLCDYMRNMSLGGNGGGDGSNSMSLMQDRMRVMGGPKHLSEADAMAIAASGNDPSVYLNALKMGSPSRLSPHSPHSPIQGGNGGNVGDGTARFSRKVFVGGLPPDIDEDEITTSFRRFGPLVVDWPHKAESKSYFPPKGYAFLLFQDESSVQQLIDSCITDEDKLYLCVSSPTIKDKAVQIRPWRLADADYVLDATMSLDPRKTVFVGGVPRPLKAFELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQLQHGDIDKRVEVKPYVLDDQMCDECEGQRCGGKFAPFFCANVTCLQYYCEHCWAVIHSRPGREYHKPLVKEGADRPRAVPFRWC
What is the function of this protein?
Required for initial memory acquisition (PubMed:26095367, PubMed:28525754).  Following subsequent late dopaminergic pathway activation, recruits isoform B into a complex to activate translation of CaMKII which is required for long-term memory consolidation (PubMed:26095367).
What are the official names of this protein?
Translational regulator orb2.
What are the subcellular locations of this protein?
Perikaryon. Cell projection, axon. Cell projection, dendrite. Synapse. Cytoplasm. Cytoplasm, perinuclear region. Note=In embryonic and larval nervous system, concentrated in the perikaryon (PubMed:21900268). In the adult central nervous system, localizes to synaptic terminals (PubMed:21900268). In the ovary, localizes to the cytoplasm of nurse cells (PubMed:21900268). Localizes to neuromuscular junctions (PubMed:29105522). In spermatocytes, localizes throughout the cytoplasm with higher levels concentrated in a ring around the nucleus (PubMed:23209437). The oligomeric form is enriched in the synaptic region (PubMed:22284910). SUBCELLULAR LOCATION: [Isoform A]: Synapse. SUBCELLULAR LOCATION: [Isoform B]: Perikaryon. Cell projection, axon. Synapse.
Protein: TRM61_CANGA
Sequence: MVEVFDKYKDLIQEGDLALIWISRDNIKPVTINANETFNTRYGSFPHKDMIGKPYGSQIAIRTKVAKKFAFVHVMQPSPELWTLSLPHRTQIVYTPDSSYIMQRLNCSPNSRVIEAGTGSGSFSHAFARSVGQLYSYEFHPVRYEQATEEFKEHGLLDKNTIITHRDVCKDGFTIKKTDETSYQFKADEEQLQIKADVIFLDLPAPWEAIPHIDSVIDNDEKVGLCCFSPCIEQVDKTLEVLEKHGWFNVEMVEIQGRQYESRRQMVRSLDDALERLSDIKKRKLAMVERRQKAEEELEKKIEANEKNLPELPPKSIEKSKFNPFGKGYRVKEGDANFQWKEVTKVESEIKSHTSYLTFAYKIKRNEDENLDKN
What is the function of this protein?
Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
What are the official names of this protein?
tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61, tRNA(m1A58)-methyltransferase subunit TRM61, tRNA(m1A58)MTase subunit TRM61.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DRD5_RAT
Sequence: MLPPGRNRTAQPARLGLQRQLAQVDAPAGSATPLGPAQVVTAGLLTLLIVWTLLGNVLVCAAIVRSRHLRAKMTNIFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGTFCDIWVAFDIMCSTASILNLCIISVDRYWAISRPFRYERKMTQRVALVMVGLAWTLSILISFIPVQLNWHRDKAGSQGQEGLLSNGTPWEEGWELEGRTENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSRGAYEPDPSLRASIKKETKVFKTLSMIMGVFVCCWLPFFILNCMVPFCSSGDAEGPKTGFPCVSETTFDIFVWFGWANSSLNPIIYAFNADFRKVFAQLLGCSHFCFRTPVQTVNISNELISYNQDTVFHKEIATAYVHMIPNAVSSGDREVGEEEEEGPFDHMSQISPTTPDGDLAAESVWELDCEEEVSLGKISPLTPNCFDKTA
What is the function of this protein?
Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
What are the official names of this protein?
D(1B) dopamine receptor, D(5) dopamine receptor, Dopamine D5 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EFP_METCA
Sequence: MAIVSTSEFKNGLKVMLDGDPCTMLESEFVKPGKGQAFNRVKLRNLKTGRVVERTFKSGETLETADVVDVEMQYLYNDGELWHFMVPESFEQYAADQNAVADAKKWLKEQDICILTLFNNVPLAVQPPNFVELTITETDPGVRGDTSGGGGKPATLETGAVVRVPLFVQTGEVIKVDTRTGEYVSRVK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_TAXTA
Sequence: MTNIRKTHPLAKIINNSFIDLPAPSNISTWWNFGSLLGVCLIIQILTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFLHVGRGLYYGSYMFPETWNIGIILLLTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIILALAAIHLLFLHETGSNNPSGIPSNSDKIPFHPYYTIKDILGALLMALLLMVLVLFSPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLFSILILAIIPLLHTSKQRSMMFRPLSQCMFWLLVADLLILTWIGGQPVEHPYITIGQLASILYFTILLALMPTISIIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: COXX_POLNS
Sequence: MSDSKKSATVVMPRWRQYWVLTKPRVTQLAVFCAVIGMFLATPGMVPYPVLFGGIVGIWLLAGAAFAVNCLIEQAVDAKMKRTSWRPSATGEVTPLHIIIFSIILGSLGMIILWNFCNPLTMWLTLATFVGYAVIYTWLLKPATPQNIVIGGLSGAMPPALGWAAVTNTLSAEAWHLVLIIFVWTPPHFWALALYRRDDYVQSGLPMLPVTHGERFTLLNIVLYTLILIAATMLPYIYGMSGMVYLISAIILGLLFLAYVVALFISYSDALAKKTFRFSITYLSLLFAALLVDHYFL
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRPF_XANCP
Sequence: MNRSLYRTRIKFCGMTRAGDIRLAGELGVDAVGFIFAHGSPRRVAPAEARAMRQATAPMVDVVALFRNNSKEEVREVVRTVRPTLLQFHGEEDDAFCRSFNLPYLKAVPMGASGVNGEDANARTLQLAYPNTAGFLFDSHAPGEGGGTGKTFDWSRLPTGLHRPFLLAGGITADNVFDAIVATLPWGVDVSSGVELAPGIKDGHKMRKFVEEVRRADCHEMS
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.