PharMolix/UniProtQA huggingface dataset:
Protein: CAHS4_HYPEX
Sequence: MSNYQQESSYQYSDRSNNGQQQEQQEKKEVEHSSYTHTDVKVNMPNLIAPFISSSAGLAQELVGEGFQASVSRITGASGELTVIDTEAETEEARRDLEAKAREQELLSRQFEKELERKTEAYRKQQEVETEKIRKELEKQHLRDVEFRKELMEQTIENQKRQIDLEARYAKKELERERNKVKRVLERSKFHTDIQVNMEAAAGSTHSGSSSVAVSESEKFQTNN
What is the function of this protein?
CAHS proteins are cytosolic heat soluble proteins that seem to contribute to the anhydrobiosis in tardigrades, but their specific mechanisms are yet to be identified (PubMed:28306513, PubMed:33545053).  It is possible that protection during anhydrobiosis might occur via the stabilization of vitrifying small molecules such as sugars, but not via the direct glass transition of CAHS proteins themselves (Probable).
What are the official names of this protein?
Cytosolic-abundant heat soluble protein 77611, CAHS 77611, Tardigrade-specific intrinsically disordered protein CAHS 77611, TDP CAHS 77611.
What is the protein family that this protein belongs to?
Belongs to the Cytosolic-abundant heat soluble protein (CAHS) family.
Protein: PA2A2_DABRR
Sequence: MRTLWIVAVCLIGVEGNLYQFGEMINQKTGNFGLLSYVYYGCYCGWGGKGKPQDATDRCCFVHDCCYGRVKGCDPKTATYSYSFENGDIVCGGDDPCLRAVCECDRVAAICFRENMNTYDKKYMLYSIFDCKEESDQC
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that is neurotoxic.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (By similarity).
What are the official names of this protein?
Acidic phospholipase A2 Drk-a2, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: IF3_STRP3
Sequence: MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADASNVDLVLIQPQAVPPVAKLMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPVIDKGDFETKLRNGRKFLEKGNKVKVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKMDGRQMFMQLAPISDKK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS1_THET2
Sequence: MRRFALTVALPKGRMFREAYEVLKRAGLDLPEVEGERTLLHGKEGGVALLELRNKDVPIYVDLGIAEIGVVGKDVLLDSGRDLFEPVDLGFGACRLSLIRRPGDTGPIRRVATKYPNFTARLLKERGWAADVVELSGNIELAAVTGLADAVVDVVQTGATLRAAGLVEVEVLAHSTARLVVNRQALKLKRAVLKPLIQRLRELSGS
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINE_STRM5
Sequence: MGLFDFLKAKKTTAETAKNRLQIIIAQERSNRGGPDYLPLLQRELLEVIKKYVNIDVDAVKVDLVKDGQHDVLDISVALPEGPDKP
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: Y3897_BACC2
Sequence: MARIGVENSLTDVQQALQQQGHEVVTLNSEQDAQGCDCCIVTGQDSNVMGIADASIKGSVITAHGLTTDEICQQVEIRT
What are the official names of this protein?
UPF0180 protein BCG9842_B3897.
What is the protein family that this protein belongs to?
Belongs to the UPF0180 family.
Protein: ZN682_HUMAN
Sequence: MELLTFRDVTIEFSLEEWEFLNPAQQSLYRKVMLENYRNLVSLGLTVSKPELISRLEQRQEPWNVKRHETIAKPPAMSSHYTEDLLPEQCMQDSFQKVILRRYGSCGLEDLHLRKDGENVGECKDQKEIYNGLNQCLSTLPSKIFPYNKCVKVFSKSSNLNRENIRHTTEKLFKCMQCGKVFKSHSGLSYHKIIHTEEKLCICEECGKTFKWFSYLTKHKRIHTGEKPYKCEECGKAFNWCSSLTKHKRIHTGEKPYKCEECGKAFHWCSPFVRHKKIHTGEKPYTCEDCGRAFNRHSHLTKHKTIHTGKKPYKCKECGKAFNHCSLLTIHERTHTGEKPYKCEECGKAFNSSSILTEHKVIHSGEKPYKCEKCDKVFKRFSYLTKHKRIHTGEKPYKCEECGKAFNWSSILTEHKRIHTGEKPYNCEECGKAFNRCSHLTRHKKIHTAVKRYKCEECGKAFKRCSHLNEHKRVQRGEKSCKYKKCGEAFNHCSNLTT
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 682.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EFP_PSEPG
Sequence: MKTGKELKPGTVLRIDNDPWLVQKAEFTKSGRNSAIMKTKLKNLLTGYKTETVYGADDKLDDVILDRKEATLSFISGDSYTFMDTTDYTMYELNAEDIDAVLPYIEEGMEDICEAVFFEGRLVSVELPTTISRQVVYTENAARGDTSGKVMKPAKLKNGTEIQVADFIQIDEWIDIDTRDNSFKGRSKK
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRP19_METS3
Sequence: MITVWPQYLDKNLSLNEGRKVSKEIAVEEPKLQDIEKALKRLNLPYSTQKERSYPGKWYEKSGRILVESDKPKLELLKEISLKLQEIKQ
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
What are the official names of this protein?
Signal recognition particle 19 kDa protein, SRP19.
What is the protein family that this protein belongs to?
Belongs to the SRP19 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LGT_BURP6
Sequence: MIIHPNFDPVAIHLGPLAVRWYGLMYLVGFIFAIVVGRLRLKLPHVAAQGWSAKDIDDMMFYGVLGVVLGGRLGYVLFYKAGYYFSHPLDIFRVWEGGMSFHGGFLGVTLAMALFAWQRKRHWLEVTDFVAPMVPTGLAAGRLGNFINGELWGRVTSPDAPWAMLFPGASRDDAAWLAAHQDIAAKWNLNEVFLSHQMLPRHPSQLYEIALEGIALFFVLWFFSRKPRPMGAISALFLIGYGAARFTVEFAREPDDFLGLLTFGLSMGQWLSLPMIVAGVLMMIWAYRRGGVAKQA
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ACDH7_RHOJR
Sequence: MTTKVAIIGSGNIGTDLMFKIQRLSQTLEVAALVGIDPESDGLQRAGRLGIPITADGVAGLLDIPGFDQISIVFDATSARAHVANAAALEPFGKQLVDLTPAAIGPYVVPAVNLEENLAARNVNMVTCGGQATIPMVAAVSHVAPVAYAEIVASIASRSAGPGTRANIDEFTETTSKAIEVVGGAHRGKAIIVLNPADPPLIMRDTILCLIGDADHDAIRDSVHRRVAEVSEYVPGYRLKQDVQITTVTDDVPLSTLGRVSQ
What are the official names of this protein?
Acetaldehyde dehydrogenase 7, Acetaldehyde dehydrogenase [acetylating] 7.
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: RF1_STRPD
Sequence: MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSREEANTRETVTAYREYKQVIQTISDAEEMIKDASGDPELEEMAKEELKESKAAKEEYEEKLKILLLPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAETQGWRFEVMESSVNGVGGIKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDIDQKDLRVDIYHASGAGGQNVNKVATAVRMVHIPTGIKVEMQEERTQQKNRDKAMKIIRARVADHFAQIAQDEQDAERKSTVGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTILSGKMDEVIDALVMYDQTKKLESLNN
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH1_MYCVP
Sequence: MTRSHNHSATITTARFDQARAEAAVRELLIAVGEDPDREGLRDTPARVARAYQEIFAGLYTDPDEVLKTMFDEQHDEMVLVKDIPMYSTCEHHLVSFHGVAHVGYIPGVDGRVTGLSKLARVVDLYAKRPQVQERLTGQIADALMRRLDPRGVIVVIEAEHLCMAMRGIRKPGAVTTTSAVRGQFKTDKASRAEALDLILRK
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: CINA_CLOB1
Sequence: MKAEILCVGTELLLGDIVNTNAQYISKELANIGIEVYHHSVIGDNENRLLKELERAFNYCDLVITTGGLGPTKDDLTKESVAKFFQEDLVLHEKSLKQIEKRLLCFNKSMTESNKKQAYFPKNCEILENPNGTAPGFIIEKDNKIAIILPGPPYEMQPMFENKVIPYLEKLTSSTIKSKVLRITGIGESDVADLISDILENQTNPTVAPYAKQGETTLRITAKANSEEKALNLIVPIEKKIRQILEDNIYGSGETSLEEVVANILVKRNLTIATAESCTGGLLAGKLINFPGISSVFLEGAITYSNESKINRLNVKKETLEKYTAVSKEVALEMAEGIAKSAGTNIGISTTGVAGPGGGTYDKPIGLIYIGLYINGKTFVKELNYSGNRQFIRNITVTRALDFLRRNLK
What are the official names of this protein?
Putative competence-damage inducible protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: LPXK_BACTN
Sequence: MDEHFIKIHKWLYPVSWIYGAVVTVRNKLFDWGFLRSKSFGVPVICIGNLSVGGTGKTPHTEYLIKLLRDNYHVAVLSRGYKRHSRGYVLATPQSTARSIGDEPYQMHTKFPSVTLAVDENRCHGIEQLLSIKEPSIEVVLLDDAFQHRYVKPGLSILLTDYHRLFCDDTLLPAGRLRESVNGKNRAQIVIVTKCPQDIKPIDYNIITKRLNLYPYQQLYFSSFRYGNLQPVFPSANSEIDSTVNELPLSALTNTDILLVTGIASPAPILEELKMYTDQIDSLSFDDHHHFSHRDIQQIKERFGKLKGEHKLIVTTEKDATRLIHHPVLSEELKPFIYALPIEIEILQNQQDKFNQHIIGYVRENTRNSSFSERENAHQS
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: MNMA1_BACFN
Sequence: MMEKNKRVLLGMSGGTDSSVAAMLLLEAGYEVTGVTFRFYEFNGSTEYLEDARALAARLGIGHITYDARKVFQEQIIDYFIDEYMSGHTPVPCTLCNNQLKWPLLAKIADEMGIFYLATGHYVRKQWIDGNYYIAPAEDVDKDQSFFLWGLRQEILQRMLLPMGGMTKSEARAYAAGRGFEKVSKKKDSIGVCFCPLDYRSFLKKCLCDESGDKNRNIYRKVERGRFLDESGNFIAWHEGYPFYTIGQRRGLGIQLNRAVFVKEIHPETNEVVLASLKSLEKSEMWLKDWNIVDESRLLGCDDVIVKIRYRKQENHCSVTITPEGLLHIRLHEPLSAIAEGQAAAFYKDGLLLGGGIITMTDQR
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA 1.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPD_PHOV8
Sequence: MNRHVIIVAGGKGLRMGGDIPKQFLPVGGKPVLMRTIEAFYAFDSSMHIILVLPVSQQAYWKDLCETYHFALRHDIADGGETRFHSVKNGLAYVKGEGLVGVHDGVRPFVSREVIAGCYEAAQTKQAVIPVIDVVETVRHLTKPGSETVPRNDYKLVQTPQVFEVQLLKEAYQQEYTDAFTDDASVVEAMGREVCLVQGNRENIKLTTPFDLKIAEVLI
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: GL_MUHVK
Sequence: MMPLLLLILLSTRNLLGAAQSQESPVAGERRALDLTTVYVLPRSEPINATVEHKCREALASCYNGSEFQPLHDDGPIRPDPYRFSTMIRFKRSYGELPLPIELNDEFLEQLSLLHNNTDQLRVLLTLMRTSRASDWMSFLGGYTQCDAPKSVVFTCVESVCYEHDLMRLNYTTDLFTENVLGLDVSPPVLSVLVLLRNNHTKAESVVRVPTSSMSMLDGTYNLLRTILGHMSLDTDLIGVLRSYRDRFPAVFSVSDQIKITRQHYRPQYQRKRP
What is the function of this protein?
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell.  Acts as a functional inhibitor of gH and maintains gH in an inhibited form.  Upon binding to host integrins, gL dissociates from gH leading to activation of the viral fusion glycoproteins gB and gH.
What are the official names of this protein?
Envelope glycoprotein L, gL.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein L family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Extracellular side. Host cell membrane; Peripheral membrane protein; Extracellular side. Host Golgi apparatus, host trans- Golgi network. Note=gL associates with the extravirion surface through its binding to gH. During virion morphogenesis, this protein probably accumulates in the host trans- Golgi where secondary envelopment occurs.
Protein: RL31_DESDA
Sequence: MKKDIHPKVFNATITCACGNEEKVLSTKGEQVNVEVCSACHPFFTGKQRFLDTAGRIDRFRKKYAKFEQK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: PSTB_SULDN
Sequence: MATIIEINKKKALEVKNFEFTYAKADVPSVKKLSMPVAKHNITALIGPSGCGKTTLLRSFNRMHDLYPNNKYSGEITFKDRNILTSKEDLIKLRIQIGMIFQKPTAFPMSIFDNVAYGLKLQGIKNRTELSGRVEKALKDAAIWNEVKDRLKHDANGLSGGQQQRLCIARAVAVEPEVLLFDEPTSALDPISTGGIEELIVELRERVSIIIVTHNMQQAARVSDYTGFMYLGELIELGKTEEIFVTPKEKLTEEYITGKFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RNAS_ARTBC
Sequence: MVSFKAILTLSLIGAAFATPIEQRAAEPVEDSGAVANSPEGSGMDLGGTDPTADAIEERGLLVRNILRQLLNNKQSGLTIISSTSNAITWLSRPPRRGRSLREYPVFQQHHKVYNYNSRPKENPGPFRLIATKDSRHFCGIISHDGIGHNPNAGLFHLCK
What is the function of this protein?
This purine-specific ribonuclease cleaves 28S RNA in eukaryotic ribosomes, inhibits protein synthesis, and shows antitumor activity.
What are the official names of this protein?
Ribonuclease ARB_07070, Major allergen Asp f 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease U2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RNZ_STRPG
Sequence: MELQFLGTGAGQPAKQRNVSSLALKLLDEINEVWMFDCGEGTQRQILETTIKPRKIRKIFITHLHGDHIFGLPGFLSSRSFQASEEQTDLDIYGPIGIKTYVLTSLKVSGARVPYQIHFHEFDDKSLGKIMETDKFVVYAERLAHTIFCMGYRVVQKDLEGTLDAEALKAAGVPFGPLFGKIKNGQDVELEDGRLICAKDYISAPKKGKIITIIGDTRKTSASVKLAKDADVLVHESTYGKGDERIARNHGHSTNMQAAQIAHEAGAKRLLLNHVSARFLGRDCRQMEKDAATIFENVKMVQDLEEVII
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: PDUF_SALTY
Sequence: MNDSLKAQCGAEFLGTGLFLFFGIGCLSALKVAGASLGLWEICIIWGLGISLAVYLTAGISGGHLNPAVTIALWLFACFPKQKVLPYIIAQFAGAFGGALLAYVLYSSLFTEFETAHHMVRGSVESLQLASIFSTYPAAALNVWQAALVEVVITSILMGMIMALTDDGNGIPKGPLAPLLIGILVAVIGASTGPLTGFAMNPARDFGPKLFTWLAGWGNMAMSGGREIPYFIVPIVAPVIGACAGAAIYRYFIGKNLPCNRCEL
What is the function of this protein?
The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low.
What are the official names of this protein?
Propanediol uptake facilitator PduF.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL18_MYCA1
Sequence: MGQSVSATRRVSRLRRHARLRKKIAGTPERPRLVVNRSARHIHVQLVNDENGTTVAAASSIEDDVRSLQGDKKARSVRVGQLIAERAKAAGIDSVVFDRGGYTYGGRIAALADAARENGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: Y1056_PYRHO
Sequence: MKFEAFKIVPVGYIRKEKNVFIEILPEFREGMEGLREGDWIKLILWFHKSDTPELRRILKVHPHGNPENPLTGVFATRSPFRPNPYTVKVHKIEGNRIYIDWIDAEDGTPVSDIKIFPERYDCPKENYQSTSRLKS
What are the official names of this protein?
Probable S-adenosyl-L-methionine-binding protein PH1056.
What is the protein family that this protein belongs to?
Belongs to the tRNA methyltransferase O family.
Protein: RS9_RHORT
Sequence: MAEEIKSFEDLKDVAAPAALQQKREPKRDAQGRSYATGRRKDAVARVWIKAGSGRITVNGRELENYFPRPVLRMVINQPFVVTNTTNQFDVVCTVTGGGLSGQAGALRHGISRALTYFDPDMRPALKAEGFMTRDPRTVERKKYGRAKARRSFQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: TGT_STRPG
Sequence: MTDYPIKYRLIKTEKHTGARLGEIITPHGTFPTPMFMPVGTQATVKTQSPEELKAIGSGIILSNTYHLWLRPGDELIARSGGLHKFMNWDQPILTDSGGFQVYSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYDYVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAADLVAMDFPGYSIGGLAVGESHEEMNAVLDFTTPLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTRIARNGTCMTSEGRLVIKNAKFAEDFTPLDHDCDCYTCQNYSRAYIRHLLKADETFGIRLTSYHNLYFLVNLMKKVRQAIMDDNLLEFRQDFLERYGYNKSNRNF
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: ACCD2_MYCTU
Sequence: MLQSTLDPNASAYDEAAATMSGKLDEINAELAKALAGGGPKYVDRHHARGNLTPRERIELLVDPDSPFLELSPLAAYGSNFQIGASLVTGIGAVCGVECMIVANDPTVKGGTSNPWTLRKILRANQIAFENRLPVISLVESGGADLPTQKEIFIPGGQMFRDLTRLSAAGIPTIALVFGNSTAGGAYVPGMSDHVVMIKERSKVFLAGPPLVKMATGEESDDESLGGAEMHARISGLADYFALDELDAIRIGRRIVARLNWIKQGPAPAPVTEPLFDAEELIGIVPPDLRIPFDPREVIARIVDGSEFDEFKPLYGSSLVTGWARLHGYPLGILANARGVLFSEESQKATQFIQLANRADTPLLFLHNTTGYMVGKDYEEGGMIKHGSMMINAVSNSTVPHISLLIGASYGAGHYGMCGRAYDPRFLFAWPSAKSAVMGGAQLSGVLSIVARAAAEARGQQVDEAADAAMRAAVEGQIEAESLPLVLSGMLYDDGVIDPRDTRTVLGMCLSAIANGPIKGTSNFGVFRM
What is the function of this protein?
Component of a biotin-dependent acyl-CoA carboxylase complex.  This subunit transfers the CO2 from carboxybiotin to the CoA ester substrate.
What are the official names of this protein?
Probable biotin-dependent acyl-coenzyme A carboxylase beta2 subunit.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
Protein: MKNK1_XENTR
Sequence: MVSSQPVPIDDGGKRRKKKRRTRAMESFTGKFADLYRLTDELLGEGAYAKVQGCVSLQNGKDYAVKIVEKKAGHSRSRVFREVETLYQCQGNKNILELIEFCEDDARFYLVFEKLRGGSILSHIQKRKHFNEREASKVVKDIASALDFLHTKGIAHRDLKPENILCEFKDKVSPVKICDFDLGSGVKLNSACTPITTPELTTPCGSAEYMAPEVVEVFTEEATFYDKRCDLWSLGVILYIMLSGYPPFVGNCGADCGWDRGEMCRVCQNKLFESIQEGKYEFPEKDWSHISNSAKDLISKLLVRDAKERLSAAQVLQHPWLQGDAPERGLPTPLVLQRNSSTKDLTIFAAEAVALNRQLSQHDSDLNEEHESFIHTVCSMRLSPPSKSRLAKRRAQAHARKGGSHLTHTTVTSQGAT
What is the function of this protein?
May play a role in the response to environmental stress and cytokines.  Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap (By similarity).
What are the official names of this protein?
MAP kinase-interacting serine/threonine-protein kinase 1, MAP kinase signal-integrating kinase 1, MAPK signal-integrating kinase 1, Mnk1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
Protein: BIOB_ACIBY
Sequence: MTLRNDWTREEIQALYEQPFLDLVFKAQQVHREHFTANTIQVSTLLSIKTGKCPEDCKYCSQSAHYDSKLEAEKRIAVEKVISEAKAAKDSGSSRFCMGAAWRNPHERDMPYVLEMVREVKALGMETCMTLGMLNQSQAERLKDAGLDYYNHNLDTSREYYSHIISTRTFDDRLNTLDYVRQAGMKVCSGGIVGLGESREDRIGLLHELATLPIHPESVPINMLVPIEGTPLADVEKLDVIEWIRTIAVARIIMPHSYIRLSAGRESLSDSDQALAFMAGANSLFSGDKLLTTPNAGEGKDQALFNKLGLTAEKPKPTVSDLSVDAMSA
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: ACYP_BACP2
Sequence: MIHYHAIITGRVQGVGFRYFVQGEAVNRGMKGWVRNTDEGHVELKVEGEQQEVLDFLKTVRKGSPFSKVTDMQMEQLPEFAHYQDFRIKG
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: CRCB_LEGPA
Sequence: MVVAPYLAVAIGGSLGAMSRYLVTIMAQNAWGIKFPYGTLLVNTLGSFLAGFFLIVLVGRFSAEESFRLFLFTGFLGAFTTFSSFAAESLFMFEQGYWFKLITNILVNNVGSLSMVFIGTLVAKYVLLGHQGSN
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MNMA_SYNJB
Sequence: MVISPHSSVSPVASPSRPRIVAALSGGVDSSTVAALLQEQGYAVEGVTLWLMRGKGQCCTEGLVDAAAVCEQLGIPHHVVDSRELFQANIVDYLVAGYAEGITPLPCSQCNKLVKFGPLLAYAREKLGISQMATGHYARVRFNAELGRYQLLRAVDRQKDQSYFLYDLSQEHLAHSLFPLGEYTKAQTRQLAARYGLVTADKPESQDLCLIETYGSMRSFLDQYLGQRPGEIVDTQGRVLGSHEGIHHYTVGQRKGLGIASSRPLYVVRIDAAMNRVVVGEREEATQAEAWVSQVNWVSIPAPTGSLAVEVQVRYRTPPVPAMVIPESPERVKLQFAEPQFGVTPGQAAVWYHGDLLLGGGILERPSP
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.