PharMolix/UniProtQA huggingface dataset:
Protein: Y4929_FRASN
Sequence: MSRPSAPRGRTELRSIHERGHERGSAGVGRTALATAWIRAGESERPDRLFDDWLAPAFVAAAGDALPLIPPDAGGRLGALAEMMNAYLAVRTRFFDDELLAAAEAGVRQVVLLAAGLDSRAFRLPWPAGTRLFEVDRPDILAFKEQVLAAGETGPRCERHAVSADLTEDWADEILDAGFRPAEPTAWLAEGIIVYLSAEEAERLLTDVTRLSAPGSRLALEDAKGLAEEMVEEARNIPPLGEFADLWKGGLEGASPAWLGDHGWRGREIDSTTVATELRRPIPAEMPVAGYFVTAQRAVGERAEGERAEG
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase Franean1_4929.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: RS19_SHEPA
Sequence: MPRSLKKGPFIDLHLLKKVEKAMEAGDKKPIKTWSRRSMIIPNMIGMTIAVHNGRQHVPVFVTDEMIGHKLGEFSPTRTYRGHAADKKAKKR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: ADIP_ORYLA
Sequence: MGDWGLTETSMDNYEISILSHVAMSPSRHNNLMSAYSLPSSKSSYSVISAFCTEDNIPQCISYINQELGSLGLAAHIQADPPGRASLNAAPALNAMYELLQIHRRSMNNVEELEKEQLKKTSTLEHMQTSNSRLKDQLELSIREKSGLHETERQLQLKLKTLQSCLKTEKDEVQKLQSIIASRASQYSHDAKRKEREAAKLKERLSQLLVDRKDKKLAIEMLNSVGRSDGKRSHWKTAKATASREAEMYKSLLSDYEASQRALMLENAELQKVLQQMKKEMMHILSPCPPLNRGGSAEESQELGDSDREERSAETSRETLDQSCEHAREQLTNSIRQQWRKLRNHVQKLDNQASLVQNQPPSNAEVIPLETHEHEVERMRLEVQQCKEFIHAQQQLLQQQLNTSFDDETAALLNGCYTLEEKERLKEEWRLFDEQKRNFEKERKNFTEAAIRLGREKRAFEEDRAAWLKHQFLSMTPFADRMRSSSSDGQSALSVKSEPEIRTSSSKAPPVKSSAYTTFSTPKSSKSAAVPSTIDVCRTLRLIPDYRESSATEDEESWLKSKSKVCSSDLSIFSLDEDKNPLT
What is the function of this protein?
Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs).  Involved in cell movement (By similarity).  Acts as a centrosome maturation factor, probably by maintaining the integrity of the pericentriolar material and proper microtubule nucleation at mitotic spindle poles.
What are the official names of this protein?
Afadin- and alpha-actinin-binding protein, ADIP, Afadin DIL domain-interacting protein, SSX2-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the ADIP family.
What are the subcellular locations of this protein?
Cell junction, adherens junction. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite.
Protein: RPOC_VARPS
Sequence: MKSLLDLFKQFTPDEHFDAIKIGMASPEKIRSWSFGEVKKPETINYRTFKPERDGLFCAKIFGPIKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIDLAAPCAHIWFLKSLPSRLGLVLDMTLRDIERVLYFEAYVITDPGMTPLKKFGIMSEDDYDAKRKEYGDEFVAKMGAEGIKDLLEGIELDSEIERLRGDLTGSEVKVKKNSKRLKVLEAFRKSGIKPEWMVLDVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNSRLRRLLELKAPEIIARNEKRMLQEAVDSLLDNGRRGKAMTGANKRALKSLADMIKGKSGRFRQNLLGKRVDYSGRSVIVVGPTLKLHQCGLPKLMALELFKPFIFSRLEAMGIATTIKAAKKEVESGTPVVWDILEEVIKEHPVMLNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSVEAQMEARTLMLASNNVLFPASGEPSIVPSQDVVLGLYYTTRDRINGKGEGLIFSDIGEVQRALDANEVELTAKVAVRITEYTKDKETGEFTPSTSLVDTTVGRALLSEILPKGLPFSNINKALKKKEISKLINVSFRKCGLKETVVFADKLLQNGFRLATKAGISIAIDDMLVPAEKHGIIERSAKEVKEIEQQYVSGLVTSGERYNKVVDIWGKAGDEVSKVMMAKLSKQKVIDRHGKEVEQESFNSIYMMADSGARGSAAQIRQVAGMRGLMAKPDGSIIETPITANFREGLNVLEYFISTHGARKGLADTALKTANSGYLTRRLVDVTQDLVVTEQDCGTHGGYLMRAIVEGGEVIESLRDRILGRSAADDVLHPENRSVLLKAGEMFDEDNIEELEAQGVDEVKVRTALTCETRFGICATCYGRDLGRGGLINIGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAVASSVEAKSNGVIGFNATMRYVTNSKNELVVIARSGEIVIHDEHGRERERHKVPYGAILAVKADQQIKAGHVLANWDPLTRPIITEFAGKTQFENVEEGLTVAKQVDEVTGLSTLVVIDPKRRGAAKVVRPQVKLIDASGAEVKIPGTDHSVTIGFPIGALVQIRDGQDVGPGEVLARIPVEGQKTRDITGGLPRVAELFEARSPKDKGMLAEMTGTVSFGKETKGKIRLQITDPEGTVWEDLVPKEKNILVHEGQVVNKGESVVDGPADPQDILRLLGSEELARYIVDEVQDVYRLQGVKINDKHIEVIVRQMLRRVVVDNIGETGYISGEQVERSEMLNTNDALRAEGKIPATFTNLLLGITKASLSTDSFISAASFQETTRVLTEAAIMGKRDELRGLKENVIVGRLIPAGTGMAYHQARKAKDQMDEAERRAIAESEAAELAGSTSDVSTTADASEGAASE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: RS10_ROSDO
Sequence: MAQSQNIRIRLKAFDYRVLDTSTQEIVNTAKRTGASVRGPIPLPNKIEKFTVLRGPHVDKKSRDQFEIRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKLQS
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: LPLA_PECCP
Sequence: MSSLRLLISDSYDPWFNLAVEECIFRQMPTTQRVLFLWRNAETVVIGRAQNPWKECNTRRMEEDGIKLARRSSGGGAVFHDLGNTCFTFMAGKPEYDKSVSTQIVLDALSALGLKASASGRNDLVVETADGVRKVSGSAYRETKDRGFHHGTLLLNADLNRLADYLNPDIKKLQAKGITSVRSRVANLVELLPSVDHQVICQAVTQAFFDYFGEQCEPEIISPSAYPDLPGFSEQFARQSSWEWNFGQAPDFSHLLDNRFTWGGIELHFDVERGVIIRAQVYTDSLNPAPLEALACALQGTAYRPENMAATCQALITAFPEQQNELQELAEWLEQSLR
What is the function of this protein?
Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.
What are the official names of this protein?
Lipoate-protein ligase A, Lipoate--protein ligase.
What is the protein family that this protein belongs to?
Belongs to the LplA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBS_NOSS1
Sequence: MQTLPKERRYETLSYLPPLTDVQIEKQVQYILSQGYIPAVEFNEVSEPTELYWTLWKLPLFGAKTSREVLAEVQSCRSQYPGHYIRVVGFDNIKQCQILSFIVHKPSRY
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, RuBisCO small subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Carboxysome. Note=This cyanobacterium makes beta-type carboxysomes (PubMed:24907906). In the carboxysome RuBisCO is organized into a paracrystalline array (By similarity).
Protein: LPTE_ECOBW
Sequence: MRYLATLLLSLAVLITAGCGWHLRDTTQVPSTMKVMILDSGDPNGPLSRAVRNQLRLNGVELLDKETTRKDVPSLRLGKVSIAKDTASVFRNGQTAEYQMIMTVNATVLIPGRDIYPISAKVFRSFFDNPQMALAKDNEQDMIVKEMYDRAAEQLIRKLPSIRAADIRSDEEQTSTTTDTPATPARVSTTLGN
What is the function of this protein?
Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.  Required for the proper assembly of LptD.  Binds LPS and may serve as the LPS recognition site at the outer membrane.
What are the official names of this protein?
LPS-assembly lipoprotein LptE.
What is the protein family that this protein belongs to?
Belongs to the LptE lipoprotein family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: ZNT5_XENTR
Sequence: MEEKYSSNVMSSGRLGPVDAPESRLTRYIVLLCFTKFLKALGIFESYDLLKVVHIVQFIFILKLGSTCFMVLFQKPFSSGKSITKRQWVSIVKHAFVSCIISLLWFFGLTLCGPLRTLLLFEHSDIVVISLLTVLFTGSGGGPSKTRGAAFFIIAVICLLLFDNDDLMAKIAEHPEGHHDSALTHFLYRAFFLLGVADHKGGVLLLVLALCFNVGFHTASRKLSLDIGGAKRLQALSHLVSVIILSPWVIILSATTESKIESWSALIMPFMTVIFSVMIMDFYVESVCSVKMEPSKCARYGSFLIFASALLLGNFWTHPITDQLRAMNKPAHQLHTEHVLSGGVVVSAIFFILSAQILASSSRKGQRGTLVGYSPEGTPLYNFMGDALHNTSPSMPRFLKDSLKQILEEYDSRQIFYFLCLNLAFTFVEIFYGVWTNSLGLLSDGFHMLFDCSALVMGLIAALMTRWKATRIFSYGYGRVEILSGFINGLFLVVIAFFVFIEAVARIYDPPDINTDMLTPVSVGGLIVNLVGICAFSHAHSHGAARGGCPSHDHGHSHHGHGHSHGHNHGHSHSDHGHNHGHTHNHGHSHGSAGVGMNANMRGVFSHVLADTLGSVGVIVSTILIRQFGWLIADPLCSLFIAVLIFGSVLPLLKDACQVILLRIPQETEKGINIALEKISNLDGLISYRDPHFWRHSASLVAGTIHVQVMSDVVEQRIIQQVTSLLKDAGVNNLTVQVEKEAYFQHMSGLSTGFQDVLIMTKQMDTIKYYKDGTYIM
What is the function of this protein?
Together with SLC30A6 forms a functional proton-coupled zinc ion antiporter mediating zinc entry into the lumen of organelles along the secretory pathway.  By contributing to zinc ion homeostasis within the early secretory pathway, regulates the activation and folding of enzymes like alkaline phosphatases and enzymes involved in phosphatidylinositol glycan anchor biosynthesis.
What are the official names of this protein?
Proton-coupled zinc antiporter SLC30A5, Solute carrier family 30 member 5, Zinc transporter 5, ZnT-5.
What is the protein family that this protein belongs to?
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein.
Protein: RL9_ANASK
Sequence: MKLILREDVENLGKGGDLVDVKPGYGRNFLLPRGLAVTANPKNVKELEHQKAVAAAKAAKLKASAQAVAKRLSETPVTLKRKVGEQDKLYGSVTALDVAEALAARGVQLDRRSIVLDEPIKTVGEFEVPVKLHSEVAGKVKVTVEAEAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: HAPX_ASPFU
Sequence: MSTPSIAPAPAPLVPALAAKPAISPSPGPGTPGSITSKEWVIPPRPKPGRKPATDTPPTKRKAQNRAAQRAFRERRAARVNELEEQIKKIEDEHEIHIAAFKEQITNLSREVEQCRSEMTWWRDRCHALEKEVSVERSAKEAIVKEFRSSLSDREAVRSDKGLAPLTTSTPQARSSDRPDNGDASNNDSGEGREEVPLGCNDCSTSHCQCIEDAFTMPGVVAQEQSRRLDTTKPGLSEPQIKPDPEEMEIDFTSRFAATQQQDQSPTSVSSPAVDPCGFCSDGTPCICAEMAAQEEQRPRRNSFENNRLAPIQNLSQFTPPPSDGDVRSDVTLPPISQATNPCANGPGTCAQCLADPRRTLFCKTLAASRSPSAAPSGCCGGKGADGGCCQSRNTNVSRGRSGSNNNTSSGSSAAPSLTLSCADAYTTLSRHPNFSRATDELSTWLPKLHTLPKPRDFPLTDRGVPRAALEVEAASVMGVLRYFDRRFADK
What is the function of this protein?
Transcription factor required for repression of genes during iron starvation (PubMed:21062375).  Represses iron-dependent and mitochondrial-localized activities including respiration, TCA cycle, amino acid metabolism, iron-sulfur-cluster and heme biosynthesis (PubMed:21062375).  Iron starvation causes a massive remodeling of the amino acid pool and hapX is essential for the coordination of the production of siderophores and their precursor ornithine (PubMed:21062375).
What are the official names of this protein?
bZIP transcription factor hapX, Iron acquisition regulator hapX.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. YAP subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: 5HT1B_CAVPO
Sequence: MGNPEASCTPPAVLGSQTGLPHANVSAPPNNCSAPSHIYQDSIALPWKVLLVVLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAFTDLLVSILVMPISTMYTVTGRWTLGQALCDFWLSSDITCCTASIMHLCVIALDRYWAITDAVGYSAKRTPRRAAGMIALVWVFSICISLPPFFWRQAKAEEEVLDCLVNTDHVLYTVYSTGGAFYLPTLLLIALYGRIYVEARSRILKQTPNKTGKRLTRAQLITDSPGSTSSVTSINSRAPEVPCDSGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGVILGAFIVCWLPFFIISLVMPICKDACWFHMAIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCTT
What is the function of this protein?
G-protein coupled receptor for 5-hydroxytryptamine (serotonin).  Also functions as a receptor for various alkaloids and psychoactive substances.  Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase.  Signaling inhibits adenylate cyclase activity.  Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways.  Regulates the release of 5-hydroxytryptamine, dopamine and acetylcholine in the brain, and thereby affects neural activity, nociceptive processing, pain perception, mood and behavior.  Besides, plays a role in vasoconstriction of cerebral arteries (By similarity).
What are the official names of this protein?
5-hydroxytryptamine receptor 1B, 5-HT-1B, 5-HT1B, Serotonin receptor 1B.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ILVD_METSB
Sequence: MPPYRSRTTTHGRNMAGARGLWRATGMKDGDFGKPIIAVANSFTQFVPGHVHLKDLGQLVAREIEAAGGVAKEFNTIAVDDGIAMGHDGMLYSLPSREIIADSVEYMVNAHCADAIVCISNCDKITPGMLMASLRLNIPVVFVSGGPMEAGKVLLGGKTKALDLVDAMVAAADDKVSEADVAAIERSACPTCGSCSGMFTANSMNCLTEALGLALPGNGSMLATHGDRKRLFVEAGHLIVDLARRYYEQDDSSVLPRSIASFAAFENAMTLDISMGGSTNTVLHLLAAAHEGEIDFTMADIDRLSRRVPVLCKVAPAVADVHVEDVHRAGGVMAILGELERAGLIHGDLPVVHAPSLKEALERWDLRRTSSESVTEFFRAAPGGVPTQVAFSQNARWKETDVDRAGGVIRDVEHAFSKDGGLAVLYGNLAEDGAIVKTAGVDASILVFSGPARVFESQDAAVEAILANQIKPGDVLVIRYEGPRGGPGMQEMLYPTSYLKSKGLGKACALITDGRFSGGTSGLSIGHVSPEAAEGGLIGLVEEGDSIQIDIPNRRLHLDISDEALAHRRTAMAEKGKGAWKPAHRTRKVSTALRAYAAMATSAARGAVRDVDQLFH
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: Y2247_MYCBO
Sequence: MAAMWRRRPLSSALLSFGLLLGGLPLAAPPLAGATEEPGAGQTPGAPVVAPQQSWNSCREFIADTSEIRTARCATVSVPVDYDQPGGTQAKLAVIRVPATGQRFGALLVNPGGPGASAVDMVAAMAPAIADTDILRHFDLVGFDPRGVGHSTPALRCRTDAEFDAYRRDPMADYSPAGVTHVEQVYRQLAQDCVDRMGFSFLANIGTASVARDMDMVRQALGDDQINYLGYSYGTELGTAYLERFGTHVRAMVLDGAIDPAVSPIEESISQMAGFQTAFNDYAADCARSPACPLGTDSAQWVNRYHALVDPLVQKPGKTSDPRGLSYADATTGTINALYSPQRWKYLTSGLLGLQRGSDAGDLLVLADDYDGRDADGHYSNDQDAFNAVRCVDAPTPADPAAWVAADQRIRQVAPFLSYGQFTGSAPRDLCALWPVPATSTPHPAAPAGAGKVVVVSTTHDPATPYQSGVDLARQLGAPLITFDGTQHTAVFDGNQCVDSAVMHYFLDGTLPPTSLRCAP
What are the official names of this protein?
Putative hydrolase Mb2247c.
What is the protein family that this protein belongs to?
Belongs to the peptidase S33 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RS2_ACIAD
Sequence: MADYNVSMRDLLQAGAHFGHQTRFWNPKMRQYIFGARNKIHIINLEHTVPALNDALNFANQLASKKNKVLFVGTKRAASNIIREQAQRAGQPYVDHRWLGGMLTNWKTLRQSINRLKDLQTQSQDGTFAKLTKREALERTREMEKLERSLGGVKNMGGLPDALFVIDVDHEAIAIKEAKNLGIPVIGIVDTNSNPDNVDYVIPGNDDAIRAVTLYASAMADAILAGKEYAQSQANAQAKGEEAPAASEA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: DOA10_SCHPO
Sequence: MNADDEICRVCRCEGAPDSPLFHPCKCTGSIRYVHQECLVEWLGHSKKTHCELCKAKFEFTKVYSESMPRTIPFTILCRKLASTLKQRVIFFTRVLLTFFCWTVLLPLIFKHVWNLNFKIGDTYTIHARNKTFTAPQKPGYFESISQITSSPRLNTLIANTAEGQVLTFVVTFILITAFLVREWVLQNAVQVADELQGQQFENVNQNNQAQAAAAAAQNLREVREARQRLAMVMEHLRERQEQRNLELQRNGSFEEIERARQRFALLGDNIREPQEEENDVDVDEIFNRQQLNQPALDLNDANSSNSVPVEFNSLHSQNVDYRDEVDSLRPQFNVDEQSSISHSSNASENIVDGAVTQANGIESDFTRVDHEPIIVNNDDENGNNESENEEVIEEDNLNRNVIAEAQNQVVADEERNAVARAAQIAEADDADDFDGILEFLGLRGPITGFLQNCLVIAFVVSVFLTTAVGIPYMSGRLMVEWILFIIHRPTFILRFILSFVNILFDWTVGGAFNIVKILTKLPLLSTVFVKLKLQGIFSSSFQQVSNNMYSWIYDHVFSSSDHAYESLIYYMKTGHKQVVQSFSIFPVFRVCQMFAVILKDFVENYSNRPVDRVFTTLIGYCMFTFLGISYLNRKQFLFNDPQIRNVELAFREVLRQCGSIAKFGIIFSIELVVFPIFCGILLSMCLIGTFKKLAAENLLNVMTVYPAQSIFLAWFIGITFMFEFAVFISMVRKIVRPGVLYFLRDPNDPQFHPIREILEKPMLFQLKKIGFSAILYFAFIIGCVGSVIHLLKSTGIIFPIEFTTKPAVFEAPIDLLALEILIFLSIKLFKPLELTRSFWRTLVSTFCRCLRLSSYVMGQRYSDEEGYYPKQYFSFLRRIISKPSDTENQDDGDKQKAKKDFVQDGFFLWCPSKDVVPVRQGAMLIPVTENGYEIFGEKKKVEENADYTITYAPSNFYKRLIALLLFCWICSTLVTVLLVFVPLSLGRAIYAWCFPNVVKHDFYAYAIGFYSISFPMYAIHASVKFLKLDYLRSLMNKLNLKIVMRSLVMALKYLLLAFLGIFILPLLLGAIWELYVAIPFRTIFNRGTLALDAFQNWVIGLFMLRMIYFTVTSNEERFVSRLFQDAFRDRWTNPQILPLLKNVLIPFTSALIAAVVLPSVFTYVTYPFLSSIFPSASKTLMYRLMHPIFLALLGLALLGRRFVETSSKWSQGIRDDLYLVGTRLHNFGESAPPAISESAEK
What is the function of this protein?
E3 ubiquitin-protein ligase which accepts ubiquitin specifically from endoplasmic reticulum-associated E2 ligases, and transfers it to substrates promoting their degradation.  Mediates the degradation of a broad range of substrates, including endoplasmic reticulum membrane proteins (ERQC), soluble nuclear proteins and soluble cytoplasmic proteins (CytoQC).  Component of the doa10 ubiquitin ligase complex, which is part of the ERAD-C pathway responsible for the rapid degradation of membrane proteins with misfolded cytoplasmic domains.  Also recognizes the N-terminally acetylated residue of proteins as degradation signal (degron).
What are the official names of this protein?
ERAD-associated E3 ubiquitin-protein ligase doa10, RING-type E3 ubiquitin transferase doa10.
What is the protein family that this protein belongs to?
Belongs to the DOA10/MARCH6 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SUC9_ARATH
Sequence: MSDIQAKEDAAPVDRQSSSSVVVPDEPSPLRKMISVASIAAGIQFGWALQLSLLTPYVQLLGVPHKWSSFIWLCGPISGLLVQPTVGYFSDRCKSRFGRRRPFIATGALLVALAVILIGFAADFGHTMGDKLDEAVKIRAVGFFVVGFWILDVANNTLQGPCRAFLGDLAAGDAKKTRTANAIFSFFMAVGNVLGYAAGSYTNLHKIFPFTVTKACDIYCANLKSCFIISITLLIVLTIIALWYVEDKQWSPNADSDNEKTPFFGEIFGAFKVMKRPMWMLLAVTALNWIAWFPFLLYDTDWMGREVYGGDSAGDDKMKKLYNHGIQVGSLGLMLNSIVLGVMSLVIGVISKKIGAKRLWGAVNIILAVCLAMTVLVTKKAEEHRKIAGRMALPTNAIRDGALSLFAILGIPLAITFSIPFALASIISSSSGAGQGLSLGVLNMAIVIPQMIVSFGVGPIDALFGGGNLPGFVVGAIAALISSVVALTVLP
What is the function of this protein?
High-affinity sucrose transporter.  Responsible for the transport of sucrose into the cell, with the concomitant uptake of protons (symport system).  Can also transport a wide range of glucosides, such as helicin, salicin, arbutin, maltose, fraxin, esculin, uranose, alpha-methylglucoside, alpha-phenylglucoside and beta-phenylglucoside.  Plays a role in flowering time transition delay.
What are the official names of this protein?
Sucrose transport protein SUC9, AtSUC9, Sucrose permease 9, Sucrose-proton symporter 9.
What is the protein family that this protein belongs to?
Belongs to the glycoside-pentoside-hexuronide (GPH) cation symporter transporter (TC 2.A.2.4) family.
Protein: CCA_STRPC
Sequence: MKLMTMPSEFQKALPILTKIKEAGYEAYFVGGSVRDVLLERPIHDVDIATSSYPEETKAIFNRTVDVGIEHGTVLVLENGGEYEITTFRTEDVYVDYRRPSQVSFVRSLEEDLKRRDFTVNALALDENGQVIDKFRGLIDLEQKRLRAVGKAEERFEEDALRIMRGFRFAASLDFDIEAATFEAMRSHSPLLEKISVERSFTEFDKLLMAPHWRKGISAMIACQAYDYLPGLKQQEAGLNHLIVSLKDNFTFSDHHQAWAYVMISLAIEDPKSFLKAWKTSNDFQRYVTKLIALYRIRQERSFEKLDIYQYGKEMASLVEGLRKAQSLSVDMDHIEALDQALAIHNKYDIVLNGSHLIKDFGMKPGPQLGLMLEKVELAIVEGRLDNDFTTIEAFVREELAT
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
Protein: PHLG_PSESP
Sequence: MEARNMTPFTYFSLPMQKLFLRNQAAVRNKPYAKYFRTEMRVPLSAVRKIQQGPMALEDTLTPSIEDINRLLEPDFVSEESGYALLPGPMAYVQSRKFFPGCTAQMFKWWFIWHPAESERYTLWFPYAHVSNPCVHHQRLCDESLSFEERLYGNTFCASEYVGDRLMHLHIDFQQPASLGLNTDLYREAKIDGSVSALMSLADHPEVPVSLMVHLFKEVPGGMYLTSRYWVGAHPSMARFPGAEKAASLLKENGFGEAELETLAYEFAVHDMCEFNHLASFLPDLYREFGTPAA
What is the function of this protein?
Hydrolase that specifically degrades the potent antimicrobial compound 2,4-diacetylphloroglucinol (DAPG) to equimolar amounts of mildly toxic monoacetylphloroglucinol (MAPG) and acetate.
What are the official names of this protein?
2,4-diacetylphloroglucinol hydrolase, DAPG hydrolase.
What is the protein family that this protein belongs to?
Belongs to the DAPG/phloretin hydrolase family.
Protein: NUDT5_ARATH
Sequence: MGLTKNFAFLVFCCQRYCSMDGEAFEISLLDGEEDRFGGTVVNLMEVESMTIGDFDSKLDVSLKAWKDQGKKGIWIKLPSELSSLVDTAIKKGFTYHHAENEYVMLTFWLPEPPSTLPCNASHRIGIGAFVLNKNGEMLVVQENSGYFKDKNVWKVPTGTIKEGESIWAGAVREVKEETDIDAEFVEVLSFMESHQAVWQRKTDIFFVCELEARTFEIQKQDSEIHAAKWMPVEEYVNQPYHNKEGNEMFKLIANICLKRSREKYTGFVLTTNSAKKSLYCSVDHANLLKETADQASTSLSD
What is the function of this protein?
Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.
What are the official names of this protein?
Nudix hydrolase 5, AtNUDT5.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
Protein: BIOD_BURO0
Sequence: MSAPLSVFVTGTDTEIGKTFVSAAMLHGFARHGLRAAALKPIAAGAYERDGVWRNEDADQLDAAANVALPPELRTPFLLKAPAAPHIVAAQEGVTLDLDTIVACHREALTRADVVVVEGVGGFRVPLNDTQDTADLAVALGLPVVLVVGVRLGCISHALLTADAIRQRGLTLAGWVANHVDPAMSFADENVATIRDWLARERRAPLIGRIAHMTPAAPESAAAMLDIAALVESLRTARH
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
Protein: RPOA2_STRAW
Sequence: MLIAQRPSLTEEVVDEFRSRFVIEPLEPGFGYTLGNSLRRTLLSSIPGAAVTSIRVDGVLHEFTTVPGVKEDVTDLILNIKQLVVSSEHDEPVVMYLRKQGPGLVTAADIAPPAGVEVHNPDLVLATLNGKGKLEMELTVERGRGYVSAVQNKQVGQEIGRIPVDSIYSPVLKVTYKVEATRVEQRTDFDKLIVDVETKQAMRPRDAMASAGKTLVELFGLARELNIDAEGIDMGPSPVDAALAADLVMPIEELELTVRSYNCLKREGVHSVGELVARSEADLLDIRNFGAKSIDEVKAKLAGMGLGLKDSPPGFDPTAAALGADDDADAGFLETEHY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: RL9_ORYSJ
Sequence: MKTILASETMEIPEGVTVQVAAKVVTVEGPRGKLTRNFKHLNLDFQLLEGGRKLQVDAWFGTRRTMAAIRTAISHVQNLITGVTKGYRYKMRFVYAHFPINASITNSNTAIEIRNFLGEKKVRKVDMLEGVTILRSEKVKDELVLDGNDIELVSRSAALINQKCHVKNKDIRKFLDGIYVSDKGTITEDA
What are the official names of this protein?
60S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: K1C16_HUMAN
Sequence: MTTCSRQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSRFSSGGACGLGGGYGGGFSSSSSFGSGFGGGYGGGLGAGFGGGLGAGFGGGFAGGDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPSEIKDYSPYFKTIEDLRNKIIAATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRVLDELTLARTDLEMQIEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEKNRRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQSQLSMKASLENSLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKTRLEQEIATYRRLLEGEDAHLSSQQASGQSYSSREVFTSSSSSSSRQTRPILKEQSSSSFSQGQSS
What is the function of this protein?
Epidermis-specific type I keratin that plays a key role in skin.  Acts as a regulator of innate immunity in response to skin barrier breach: required for some inflammatory checkpoint for the skin barrier maintenance.
What are the official names of this protein?
Keratin, type I cytoskeletal 16, Cytokeratin-16, CK-16, Keratin-16, K16.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.