PharMolix/UniProtQA huggingface dataset:
Protein: ACRB_ASPCL
Sequence: MPRSSATARKNQSNRNENGASSGKKVAKQKSNGHLNGSLNGGSTPGSVSSSQVDLPSSRSTSDSAIAPAAAASSNLNGISDSSKEDCNGREKLNGYTKGNADMSYVQTNGAGSQNGGDHAGQASHRTDKSATGAKRSTSNASINPLQLASTILKSCPMYDTIAILIFLLQLPPMVLTLVQFLFASLTFMPPSGASAGSLSSNFDIFQGPAGTPSLSTMIAMDGFCLLIWALLMWTWAQNFALDLAHVQVAITLGGGGSGKNGGVNTLCVGIVLILHLIRSKGIQDFVIGHLLSSNIISPDLLAQYSHLLPTEFRRTESQTSPSWIRSLLAVHILAQAGTAMARRSMAKNRSPNPPRPGKRVDTEASAGSQTQIDSAFESGASVSSYLGPDGQLITPTAHKDGRDRLLSAKKRRRQANQVRSRQPFWAALASTKVTVMREYEHSRALSKTARGLPMTENDLQGVSFDDGLVWITDVDASTIKFAAGDFASADDSGLSGACEDGRLGNEEIEPFYVCVNGALWATATISRVPDAQKGSGMVHWRGEVSGLAPNCAYTCSFMRSDTDEEICAISVKTPVTNDTEQFSLVSPPPQPSYRPSSPTTTLKNSIVNAEAKLNEKRSRLRKAKNDHKLIISKIRKELDNYNHRLHSGTDENRQKQRSLQLERNIRQTEEATALLEGQLDSLENIPEEELREWSDQKAKYDQELQLLNSAKEELVSARSAVAREVSSLESDLGSTVQRRERLQSRRTRVNEQYERIVSANAQGLNERERRAAEQFAREQDQAKLEANFNEQFGSIGQSVQEYQLRAQQIWQQCDAIEQAIQQQQQRMLLDSAPLTPEGNLPGTNPFSETSALPLGALTSTAPNSRSLLGLSFPAIKSSPLQTISSALDASSSHPTSPVQPPSFLNFPASPLVNATSHLDSDFTYRDRSFSNRSARSSLYGSEFLDSSRRQPFQIDLPELLGEKRNSGSDSTALKSGLRPVSSPFQRAGSRGSGSGSNGSGGSGSGSGSPSSAYGKPN
What is the function of this protein?
Component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB.  Involved in resistance to acriflavine, and required for normal growth on a range of sole carbon sources, including fructose, cellobiose, raffinose, and starch, and reduced utilization of amino acids, including GABA and beta-alanine, as sole carbon and nitrogen sources (By similarity).
What are the official names of this protein?
Probable ubiquitination network signaling protein acrB, Acriflavine resistance protein B.
What is the protein family that this protein belongs to?
Belongs to the acrB family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RPOC_RICAH
Sequence: MSVVNFYGQLSNTQQFDQIRINIASPDQVRSWSFGEVTKPETINYRTFKPEKDGLFCARIFGPVKDYECLCGKYKRMKNRGITCEKCGVEVTVSRVRRERMGHIELAAPVAHIWFLKSLPSRISTLLDMTMRDVEKILYFENYVVIDPGLSILQKGELLTEEELQKAKDKYGEDAFTASIGAEVIQQMLKELDFAKLKHELYEELQTTSSEVKKKKIVKRLKLVEDFLESENKPEWMIMDVLPVIPPEIRPLVMLDGGRFATSDLNELYRRVINRNNRLKKLIESKAPDIIVRNEKRMLQEAVDALFDNGRRGRAAKNANKRPFKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLHQCGLPKKMALELFKPFIYSKLELYGIATTIKAAKRMVEAEKPEVWDVLEEVIREHPVLLNRAPTLHRLGIQAFEPLLIEGKAIQLHPLVCAAFNADFDGDQMAVHIPLSIEAQLEARVFMMSTNNILSPANGRPIIVPDKDIVLGLYYLTLAFDNEVGEGMMFSDLAEMEHALYNKFITIHTKIKYRRNQLNAEGKMVHVIIDTTYGRLMVGELLPSNPNIEFKFINKQLTKKDISLVIDLVYRHCGQKATVIFADQLMKLGFKYACSSGISFGMDDMVVPESKSTHINETQLEIKEFEQQYSNGLITYGEKYNKVVDAWSRCTDRVANDMMKEIATPRVSDEPNHQKINAIYMMAISGARGSFQQIKQLGGMRGLMTKSNGQIIQTPIISNFKEGLTEFECFNSANGMRKGQIDTALKTASSGYLTRKLVDVAQDCIITEKDCGTDKGIEVKSVIEGGEVIVPSSEKILGRTAAIDIFHPVTNALILNKGELINEAKLEQIESAGLDRIMIKSVLTCESTTGICSICYGRDLATGTLVSEGEAIGVIAAQSIGEPGTQLTMRTFHIGGAATKGAEVSSVEASYGAKVKIISRNVVINSEERKIVMSRNCELLLLDNNGNEKARHKIPYGARLLVDDGDMVVKTQKLAEWDPYTIPIITEKSGKVLFKDMVEGISIRDVTDEATGIPSKVIIESKQYSRGAELRPRIQLLDAEGAVITLSNGLEARYYLPVGAVLSVEDGVQISVGDIIARIPKESTTTKDITGGLPRVAELVEARRPKDHAVIAEVDGRVEFGKDYKSKRRIIIHPIDETMSIEYMVPKGKHVVVNEGDFVKKGDLLIDGNPVLQDILKVMGVEVLANYIVKEVQAVYRLQGVKIDDKHIEVIIRQMLQKVEITDSGGTTLLAGEKIDRHEFEEINKKAIKNGLKPAAAQLILQGITKASLQTRSFISAASFQETTRVLTEAAIAGKVDKLRGLKENVIVGRLVPAGTGYFMDKMRKAAVKLDEENI
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: BETA_ACIBY
Sequence: MNIKEYDYIIIGAGSAGNVLAARLTEDKDTTVLLLEAGGPDYRLDFRTQMPAALAYPLQGRRYNWAYLTDPEPHMNNRRMECGRGKGLGGSSLINGMCYIRGNAMDLEQWATHKGLENWTYADCLPYYKKAETRDIGGNDYHGDSGPVSVATPKNGNNVLFHAMVEAGVQAGYPRTDDLNGYQQEGFGPMDRTVTPKGRRSSTARGYLDMAKGRPNLTILTHATTNKILFNQKQAIGVEYIIGADQNNLQRALVKREVLLCAGAIASPQILQRSGVGQSTFLKSMDIDVVHDLPGVGENLQDHLEMYLQYKCKQPVSLYPALKWYNQPAIGAEWLFNGTGIGASNQFEAGGFIRSSDEFKWPNIQYHFLPVAINYNGSNAVKEHGFQAHVGSMRSPSRGRIKLKSKDPFAHPSILFNYMSTEQDWREFRDAIRITREIMHQPALDPYRGDEISPGKHLQTDAELDDFVRNHAETAYHPSCSCKMGEDEMAVVDGQGRVHGMNGLRVVDASIMPLIITGNLNATTIMIAEKIADQIRGREALPRSTAPFYVAS
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
What are the official names of this protein?
Oxygen-dependent choline dehydrogenase, CDH, CHD, Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: CYB_CHARD
Sequence: MTITRKSHPLMKMVNHAFIDLPAPSNISSWWNFGSLLGLCLMIQIASGLFLAMHYTSDTLTAFSSVAHICRDVNYGWLIRYIHANGASLFFVCLYLHIGRGIYYGSYMYKETWNIGIILLFLTMATGFMGYVLPWGQMSFWGATVITNLLSAIPYVGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIIAAMAMVHLLFLHETGSNNPLGIPSDSDKIPFHPYYTTKDLLGVFILLALFLTFVLFFPDLLGDPDNYSPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVIALVLSILVLALFPLLHTANQRSMMFRPISQILFWTLVSDLMILTWIGGQPVEPPFIIIGQIASILYFSIILVLMPMAGFIENKLMKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TRUA_AROAE
Sequence: MRIVLGVEYAGSAFEGFQSQAHGRTVQDHLEAAIGHIAAHPVRLHCAGRTDAGVHATAQVVHFDTESVRPNSGWVRGVNSRLSSPVVVRWATEAGDGFHARFCAVSRRYRYILHNSPVRPALLAGRVGWFHPPLDEIAMAEAARCLEGWHDFSAFRAAGCQAKSPVKLMHEVRVQRAGDYVVFDFWANAFLHHMVRNLVGALVYVGKGRHSAAWLAEVLAARDRSLAALTFSADGLYLCGVEYAPHWSLPGEGRIIVVPRIPFV
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: PBPA_NEICI
Sequence: MIKKIVTTCFGLVLGLCVFGVGLVAIAILVTYPKLPSLDSLQHYQPKMPLTIYSADGEVIGIYGEQRREFTKIGDFPEVLRNAVIAAEDKRFYQHWGVDVWGVARAVVGNIVAGGVQSGASTITQQVAKNFYLSSEKTFTRKFNEALLAYKIEQSLSKDKILELYFNQIYLGQRAYGFASAAQIYFNKDVRELTLAEVAMLAGLPKAPSAYNPIVNPERAKLRQKYILNNMLEEKMITLQQRDQALNEELHYERFVQKIDQSALYVAEMVRQELYEKYGEDAYTQGFKVYTTVRTDHQKVATEALRKALRNFDRGSSYRGAESYIDLSKGEDVEETVSQYLSGLYTVDKMVPAIVLDVTKRKNVVIQLPSGKRVTLDGRSLGFAARAVNNEKMGESRIRRGSVIRVRNNGGRWVVVQEPLLQATLVSLDAKTGAVRALVGGYDFHSKTFNRAAQAMRQPGSTFKPFIYSAALSKGMTASTMVNDAPISLPGKGANGSVWTPKNSDGRYSGYITLRQALTASKNMVSIRILMSIGVGYAHEYIQRFGFKPSELPASLSMALGTGETTPLKIAEAYSVFANGGYRVSSHVIDKIYGSDGRLRAQMQPLVAGQNAPQAIDPRNAYIMYKIMQDVVRVGTARGAAALGRSDIAGKTGTTNDNKDAWFVGFNPDVVTAVYIGFDKPKSMGRAGYGGTIAVPVWVDYMRFALKGGQGKGMKVPEGVVSSNGEYYMKERMVTDPGLVVDNSGIAAQPSRRIREDKEAGAEDVERGAADEVRQEVQETPVLPSNTGSKQPQLDSLF
What is the function of this protein?
Cell wall formation.  Synthesis of cross-linked peptidoglycan from the lipid intermediates.  The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
What are the official names of this protein?
Penicillin-binding protein 1A, PBP-1a, PBP1a.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transpeptidase family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: CH10_HAEIE
Sequence: MNIRPLHDRVIIKREEVETRSAGGIVLTGSAATKSTRAKVLAVGKGRILENGTVQPLDVKVGDTVIFNDGYGVKSEKIDGEEVLIISENDILAIVE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHAM_BURO1
Sequence: METIAFRMHLHPGKRDEYRRRHDAIWPELADALRAAGISDYWIFLDDDTHHLFAVLKRPADHRIAQLAETDVMRRWWAYMADLMATGPDGRPVEKALEPMFHLE
What is the function of this protein?
Involved in the anomeric conversion of L-rhamnose.
What are the official names of this protein?
L-rhamnose mutarotase, Rhamnose 1-epimerase, Type-3 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose mutarotase family.
Protein: Y3385_CAUVN
Sequence: MTPRKPFWQTKTLAEMTVPEWESLCDGCGLCCLVRFEDEDTGEIIPTRVHCQLFDERLCRCKDYPNRKKTVPDCIKLTPYNIEDLEWMPPSCAYRRLHEGKDLPLWHPLVTGDPESTHKAGVSIRNQTVSELSFKDAEDAMDFVATDLMRDRGDDLYEPEEG
What are the official names of this protein?
UPF0260 protein CCNA_03385.
What is the protein family that this protein belongs to?
Belongs to the UPF0260 family.
Protein: SPED_ECOBW
Sequence: MKKLKLHGFNNLTKSLSFCIYDICYAKTAEERDGYIAYIDELYNANRLTEILSETCSIIGANILNIARQDYEPQGASVTILVSEEPVDPKLIDKTEHPGPLPETVVAHLDKSHICVHTYPESHPEGGLCTFRADIEVSTCGVISPLKALNYLIHQLESDIVTIDYRVRGFTRDINGMKHFIDHEINSIQNFMSDDMKALYDMVDVNVYQENIFHTKMLLKEFDLKHYMFHTKPEDLTDSERQEITAALWKEMREIYYGRNMPAV
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
Protein: GMHA_BURMA
Sequence: MENRELTYITNSIAEAQRVMAAMLADERLLATVQKVADACIASIAQGGKVLLAGNGGSAADAQHIAGEFVSRFAFDRPGLPAVALTTDTSILTAIGNDYGYEKLFSRQVQALGNKGDVLIGYSTSGKSPNILAAFREAKAKGMTCVGFTGNRGGEMRELCDLLLEVPSADTPKIQEGHLVLGHIVCGLVEHSIFGKQ
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_SALTI
Sequence: MTAIAPVITIDGPSGAGKGTLCKAMAEALQWHLLDSGAIYRVLALAALHHHVDLASEDALVPLASHLDVRFVSTDGNLEVILEGEDVSGEIRTQEVANAASQVAAFPRVREALLRRQRAFREAPGLIADGRDMGTVVFPDAPVKIFLDASSEERAHRRMLQLQENGFSVNFERLLAEIKERDDRDRNRAVAPLVPAADALVLDSTRLSIEQVIEKALQYARQKLALA
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARFN_ORYSJ
Sequence: MGIDLNTVEEEAEEGAAAAVCGELWHACAGPGVALPRRGSALVYLPQAHLAADGGGGEVPPAGAAAVPPHVACRVVGVELRADAATDEVYARLALVAEGEMLQRNFREGGGEDGAGEMEGCDAEKKPRMPHMFCKTLTASDTSTHGGFSVPRRAAEDCFPPLDYKTVRPSQELIAVDLHGTQWKFRHIYRGQPRRHLLTIGWSSFVNRKKLVSGDAVLFLRGDDGQLRLGVRRAVQLRNEALFEPVNSSDSKLRILSSVASSLENKSVFHICFNPRSGASEFIVPYWRLLKSLNHPFSIGMRFRVCYESEDANERSAGLISGISEVDPIRWPGSRWKCLLVRWDDSTDSSHQNRVSPWEIERVGGSVSVTHSLSSGSKRTKLHFPQGSLDTPFLNGNGHPDSMGTENFHRVLQGQEFRGSRSHGVVCSESPGVPNFQSPDNRRFSADMRGYMMPASGPPQRNTEFTYQPIGFSESLGFPEVLQGQEMSQVVPLFRGATFGARTQNDRVVSANSVHRSAAQSGLLASTLGHPISQFTLSSSKVSSPSSVLMFNQATAPNHETVSGTNNKGMHVSQFASQEMLSETVTWPGTQRQTPSEITSNQFALARIPAPPSGAESGLPKRDAGRSSCRLFGFSLTGNMLGEDGEGLDDGAIEAGCENPPVLELFGHSHSTPGALHALCAAAPLGM
What is the function of this protein?
Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs).
What are the official names of this protein?
Auxin response factor 14.
What is the protein family that this protein belongs to?
Belongs to the ARF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GUAA_GEOSL
Sequence: MSTDIHTEKILILDFGSQYTQLIARRVREAHVYCELHPFDMGLEAIRAFAPKGIILSGGPKSVYEEGAPAVEEALFDLGVPVLGICYGMQLMSRHFGGEVVPAGKREFGHADLLAAGTPGPLFEGFFVEGKSPVWMSHGDHVSRMPQGFQVVAETANAPVCAIQDTARNLYGVQFHPEVNHTPRGEILIDTFVRKICGCTGQWTPGHIIEDAVNRIRAQVGRERVILGLSGGVDSSVAAALIHRAIGDQLTCVFVDNGLLRLAEGDQVMATFAENLGVKVIRVDAEQRFLTALADEADPEKKRKIIGNLFVEIFEEESSRIEGATWLAQGTIYPDVIESAGAKTGKAHNIKSHHNVGGLPEYMKLKLLEPLRELFKDEVRAIGEELGLPRQMVWRHPFPGPGLGVRILGEVKKEYADILRRADAIYIEELYAAGHYDKISQAFAVFLPVKSVGVMGDGRTYEYVIALRAVETKDFMTAGWYPLPYEDMARISGRIINEVKGVNRVVYDISSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: RL16_PARP8
Sequence: MLQPKRRKYRKEQKGRNTGVATRGNAVSFGEYGLKAIGRGRLTARQIEAARRAMTRHIKRGGRIWIRIFPDKPISQKPAEVRMGNGKGNPEYYVAEIQPGKMLYEMDGVSEELAREAFRLAAAKLPLKTTFMVRQLGA
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: KITH_CLOB6
Sequence: MYGPKDHGWIEVVAGPMYSGKTEELIRRIRRAEIAKQKVQVFKPEIDNRYSKQDVVSHAGDKIQSVPVKSSKEILEKLLDDTDVIGIDEAQFFDDSLVEIVSKIANNNRRVICAGLDMDFKGEPFGPMPKLMAIAEFVDKIQAVCMVCNNPATRTQRLINGKPAKKSDPVVLIGAQESYEARCRKCHCVPR
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSRP5_SPIOL
Sequence: MALLSPLLSLSSVPPITSIAVSSSSFPIKLQNVSVALLPSFGQRLVAHGPVIAQKRGTVVAMVSAAAEETAGEDGDQSKVEEANISVQNLPLESKLQLKLEQKIKMKMAKKIRLRRNRLMRKRKLRKRGAWPPSKMKKLKNV
What is the function of this protein?
Component of the chloroplast ribosome (chloro-ribosome), a dedicated translation machinery responsible for the synthesis of chloroplast genome-encoded proteins, including proteins of the transcription and translation machinery and components of the photosynthetic apparatus.
What are the official names of this protein?
50S ribosomal protein 5 alpha, chloroplastic, 50S ribosomal protein L40, CL40, Chloroplastic large ribosomal subunit protein cL37, Plastid-specific 50S ribosomal protein 5 alpha, PSRP-5.
What is the protein family that this protein belongs to?
Belongs to the chloroplast-specific ribosomal protein cL37 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CYSD_KLEP3
Sequence: MDQKRLTHLRQLEAESIHIIREVAAEFSNPVMMYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTELDIWQYIYLENIEIVPLYLAAERPVLERDGMLMMIDDDRIDLQPGEVIEKRMVRFRTLGCWPLTGAVESEAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: ATG3_RAT
Sequence: MQNVINTVKGKALEVAEYLTPVLKESKFKETGVITPEEFVAAGDHLVHHCPTWQWATGEELKVKAYLPTGKQFLVTKNVPCYKRCKQMEYSDELEAIIEEDDGDGGWVDTYHNTGITGITEAVKEITLESKDSIKLQDCSVLCDEEEEEEEGEAADMEEYEESGLLETDEATLDTRRIVEACKAKADAGGEDAILQTRTYDLYITYDKYYQTPRLWLFGYDEQRQPLTVEHMYEDISQDHVKKTVTIENHPHLPPPPMCSVHPCRHAEVMKKIIETVAEGGGELGVHMYLLIFLKFVQAVIPTIEYDYTRHFTM
What is the function of this protein?
E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt), autophagy, and mitochondrial homeostasis.  Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A).  The ATG12-ATG5 conjugate plays a role of an E3 and promotes the transfer of ATG8-like proteins from ATG3 to phosphatidylethanolamine (PE).  This step is required for the membrane association of ATG8-like proteins.  The formation of the ATG8-phosphatidylethanolamine conjugates is essential for autophagy and for the cytoplasm to vacuole transport (Cvt).  Preferred substrate is MAP1LC3A.  Also acts as an autocatalytic E2-like enzyme, catalyzing the conjugation of ATG12 to itself, ATG12 conjugation to ATG3 playing a role in mitochondrial homeostasis but not in autophagy.  ATG7 (E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with ATG3 (By similarity).
What are the official names of this protein?
Ubiquitin-like-conjugating enzyme ATG3, Autophagy-related protein 3, APG3-like, Preconditioning-inducible gene 1 protein.
What is the protein family that this protein belongs to?
Belongs to the ATG3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_LACLA
Sequence: MLDIKKIRADFDGVAAKLATRGVEKEKLEKLHDLDIKRRELIVKSEALKAERNSVSDEISQVKRAKGDASAQIAAMQKVSAEIKAIDAELAEIEENLNEIIIMLPNLPHESTPIGADEDDNVEVRRVGQTPTFNFEPKAHWDLGEDLGILDWERGGKVTGSRFLFYKGAGARLERALYNFMLDEHGKEGYTEMITPYMVNQESMFGTGQYPKFKEDTFELKDDRGFVLIPTAEVPLTNYYRGEILDGAELPIKFTAMSPSFRSEAGSAGRDTRGLIRLHQFHKVEMVKFAKPDQSYDELEKMTANAENILQKLGLAYRVVALSTGDMGFSAAKTYDLEVWIPAQNTYREISSCSNCEDFQARRAQIRYRDEEGKVQLLHTLNGSGLAVGRTVAAILENYQNEDGSITVPEVLRPYMGGLEVIK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DMSB_SHIFL
Sequence: MTTQYGFFIDSSRCAGCKTCELACKDYKDLTPEVSFRRIYEYAGGDWQEDNGVWHQNVFAYYLSISCNHCEDPACTKVCPSGAMHKREDGFVVVDEDVCIGCRYCHMACPYGAPQYNETKGHMTKCDGCYDRVAEGKKPICVESCPLRALDFGPIDELRKKHGDLAAVAPLPRAHFTKPNIVIKPNANSRPTGDTTGYLANPKEV
What is the function of this protein?
Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.
What are the official names of this protein?
Anaerobic dimethyl sulfoxide reductase chain B, DMSO reductase iron-sulfur subunit.
Protein: SRY_FELCA
Sequence: MLRVLSSDEHREAVQQQNILAVEGTSCELCTESPTSNYRCETRGKGRDRGQDRVKRPMNAFMVWSRDQRRKVALENPQTQNSEISKQLGYQWKMLTQAEKWPFFEEAQRLQALHREKYPGYRYRPRRKARPEKSDKLPPADASSTLCSQLHAGERLYAFPYKDGCTKAAHSGMKDQLYSSSEPMSITSSLLEPGPHRTSTTLQDSPEDLAMQLSADAPLYRTLELGVSEAYFAW
What is the function of this protein?
Transcriptional regulator that controls a genetic switch in male development.  It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells.  Involved in different aspects of gene regulation including promoter activation or repression.  Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.  SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending.  Also involved in pre-mRNA splicing (By similarity).  In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity).
What are the official names of this protein?
Sex-determining region Y protein, Testis-determining factor.
What is the protein family that this protein belongs to?
Belongs to the SRY family.
What are the subcellular locations of this protein?
Nucleus speckle. Cytoplasm. Nucleus.
Protein: LPXD_CHLTB
Sequence: MSRSTYSLEQLADFLKVEFQGNGATLLSGVEEIEEAKTAHITFLDNEKYAKHLKSSEAGAIIISRTQFQKYRDLNKNFLITSESPSLVFQKCLELFITPVDSGFPGIHPTAVIHPTAIIEDHVCIEPYAVVCQHAHVGSACHIGSGSVIGAYSTVGQHSYIHPRVVIRERVSIGKRVIIQPGAVIGSCGFGYVTSAFGQHKHLKHLGKVIIEDDVEIGANTTIDRGRFKHSVVREGSKIDNLVQIAHQVEVGQHSMIVAQAGIAGSTKIGNHVIIGGQAGITGHICIADHVIMMAQTGVTKSITSPGIYGGAPARPYQEIHRQVAKVRNLPRLEERIAALEKLVQKLEALSEQH
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: TRMA_YERPB
Sequence: MTPNILPIESYDHQLAEKSARLKAMMLPFQAPEPEIFRSPADHYRMRAEFRVWHDEDDLYHIMFDQQTKQRIRVEQFPVASRLINRLMDALMTAIRAEPLLRRKLFQIDYLSTLSGKLIASLLYHRQLDEEWQQKALELRDQLRAQGFDLQLIGRAAKTKIMLDHDYIDEVLPVAGREMIYRQVENSFTQPNAAVNIHMLEWALDVTQGATGDLLELYCGNGNFSLALARNFERVLATEIAKPSVAAAQYNIAANNIDNVQIIRMSAEEFTQAMQGVREFNRLKGIDLGSYNCETIFVDPPRSGLDHETVKLVQAYPRILYISCNPETLCANLEQLQHTHKISRLALFDQFPYTHHMECGVLLEKRH
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: DAPD_LEPCP
Sequence: MSSQLQQVIEAAWEDRANLSVASAPAAVREAVAHVLGELDAGRIRVAERQAVGQWQVNQWVKKAVLLSFRLNDNVVMGDGALTFFDKVPSKFGGMDEAALRATGVRVVPPAVARRGSFIARGAILMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQAGPTIIEDNCFIGARSEVVEGVVVEENSVISMGVYIGQSTKIYDRATGEVTYGRIPSGSVVVSGNLPSADGKYSLYCAVIVKRVDAQTRAKTSINDLLRG
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.