PharMolix/UniProtQA huggingface dataset:
Protein: MURB_LIGS1
Sequence: MTTNDLRELFLDLNVKFDEELKKYTNTKTGGKADVLAFPDSIEETEKLIKIAKKNNVPLTILGNASNLIVKDGGIRGLVVILQHLDQITVDGTKVTAQAGASLIGTTRVAAKHSLTGMEFASGIPGSIGGAIFMNAGAYGGEIKNIVESVKLLTRDGEYKTYTVDELDFGYRHSRLQSEDDIVVAATFKLEHGDIKKIRERMEELSFLRASKQPLEYPSCGSVFKRPAGHFTGKLVYDSGLQGYTVGGVQVSKKHAGFIVNIGNGTGKDYLDVIHHVQAVVKEKFDVELETEVRIIGED
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UTP18_ARATH
Sequence: MSLSQNAPKSKGIKREELKKQYEDVEDEEEIGSDDDLTRGKRRKTEKEKQKLEESELVEMKKLENLIFGSLYSPVTFGKEEEEDGSALFHVDRSAVRQIPDYEDDGDDDEELSDEENGQVVAIRKGEAAWEDEEEKQINVDIASVNRLRKLRKEENEGLISGSEYIARLRAHHAKLNPGTDWARPDSQIVDGESSDDDDTQDGGVDDILRTNEDLVVKSRGNKLCAGRLEYSKLVDANAADPSNGPINSVHFHQNAQLLLTAGLDRRLRFFQIDGKRNTKIQSIFLEDCPIRKAAFLPNGSQVIVSGRRKFFYSFDLEKAKFDKIGPLVGREEKSLEYFEVSQDSNTIAFVGNEGYILLVSTKTKELIGTLKMNGSVRSLAFSEDGKHLLSSGGDGQVYVWDLRTMKCLYKGVDEGSTCGTSLCSSLNGALFASGTDRGIVNIYKKSEFVGGKRKPIKTVDNLTSKIDFMKFNHDAQILAIVSTMNKNSVKLVHVPSLTVFSNWPPPNSTMHYPRCLDFSPGSGFMAMGNAAGKVLLYKLHHYQNA
What is the function of this protein?
Involved in nucleolar processing of pre-18S ribosomal RNA.
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 18 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat UTP18 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ACKA_CROS8
Sequence: MSSKLVLVLNCGSSSLKFAIIDALNGDEYLSGLAECFHLPEARIKWKMDGGKHEAALGAGAAHSEALNFIVNTILAQKPELSAQLTAIGHRIVHGGEKYTSSVVIDETVIQGIKDSASFAPLHNPAHLIGIAEALKSFPHLADKNVAVFDTAFHQTMPEESYLYALPYKLYKEHGIRRYGAHGTSHFYVTQEAAKMLNKPVEEVNIITCHLGNGGSVSAIRNGKCVDTSMGLTPLEGLVMGTRSGDIDPAIVFHLHDALGMSVDDINKLLTKESGLLGLTEVTSDCRYVEDNYATKEDAKRAMDVYCHRLAKYIGSYTALMEGRLDAVVFTGGIGENAAMVRELSLGKLGVLGFEVDHERNLAARFGKSGFINKEGTTLAMVIPTNEELVIAQDACRLTA
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOD_LEGPL
Sequence: MIELKNYTLNFGPQHPAAHGVLRLVLELEGETIVRADPHIGLLHRATEKLAETKPYIQSIGYMDRLDYVSMMCNEHAYVMAIEKLLGIEPPLRAKYIRTMFDEVTRILNHLLWLGATALDIGAMTVFLYCFREREDLFDCYEAVSGARMHATYYRPGGVARDLPDTMPQYKPSRWHSEREIEKKNHNRQGSLLDFLWDFTERFPHCVDEYETLLTDNRIWKQRTVDIGVVSPENALQWGFTGPMLRGSGIAWDLRKKQSYAAYDRVEFDIPVGKTGDCYDRYLVRVEELRQSNRIIRQCIEWLRKHPGPVKVDDYKVSPPRRVVMKHDMEALIHHFKLFTEGFCLPRGEVYSSVEAPKGEFGIYMVSDGANKPYRLKIRAPGFAHLSSFDDMVRGHMLADGVAILASQDIVFGEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SPX_BACSU
Sequence: MVTLYTSPSCTSCRKARAWLEEHEIPFVERNIFSEPLSIDEIKQILRMTEDGTDEIISTRSKVFQKLNVNVESMPLQDLYRLINEHPGLLRRPIIIDEKRLQVGYNEDEIRRFLPRKVRSFQLREAQRLAN
What is the function of this protein?
Induces the expression of a large number of genes in response to a variety of stress conditions, such as disulfide, heat and cell wall stress, while concurrently repressing transcription of genes involved in various developmental and growth-related pathways during periods of extreme stress (PubMed:12642660, PubMed:14597697).  Functions in the oxidative stress response via induction of the transcription of thioredoxin (trxA) and thioredoxin reductase (trxB) during thiol-specific oxidative (disulfide) stress (PubMed:14597697, PubMed:15659166, PubMed:18687074).  Mediates response to oxidative stress caused by paraquat (PQ) via induction of the methionine sulfoxide reductase genes, msrA and msrB (PubMed:18662407).  Also acts as a transcriptional activator of the bacillithiol (BSH) biosynthesis genes in response to oxidizing conditions and thio-reactive compounds (PubMed:23894131).  Involved in heat stress response and thermotolerance development, which results in diminished cellular protein aggregates (PubMed:24417481).  Plays an important adaptive role in the cell wall stress response (PubMed:29271514).  Participates in sulfate-dependent control of organosulfur metabolism.  Negatively controls, via CymR, the expression of the organosulfur utilization operons ytmI, yxeI and ssu, and directly activates yrrT operon expression during growth in medium containing methionine as sole sulfur source (PubMed:16885442).  Negatively affects competence and sporulation (PubMed:11703662, PubMed:12028382).  Inhibits biofilm formation in response to disulfide stress by repressing biofilm matrix genes (PubMed:30718304).
What are the official names of this protein?
Global transcriptional regulator Spx, Redox-responsive transcription factor Spx, Suppressor of clpP and clpX, Spx.
What is the protein family that this protein belongs to?
Belongs to the ArsC family. Spx subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADD_YERPY
Sequence: MPIKSSDHSLYALFGGTFDPIHYGHLKPVEALAQQVGLQHIILLPNHVPPHRPQPEANAQQRLKMVELAVAGNPLFSVDSRELLRDSPSFTIETLEALRKERGAEQPLAFIIGQDSLLSLHKWHRWQALLDVCHLLVCARPGYSQSLETPELQQWLESHKVMDPQALSQRPHGAIYLADTPLLDISATDIRRRRHNGESCDDLLPQAVQRYIELQGLYRG
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: RL35_LEVBA
Sequence: MPKMKTNRAAAKRFKVTAKGGIKSANAYTSHRFHGKTKKQRRNLRGTRMMNETTIKTYHELLQK
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: EFG_ALKEH
Sequence: MARKTPIERYRNIGIMAHIDAGKTTATERILFYTGISHKIGETHEGAAVMDWMSQEQERGITITSAATTAFWQGMDQQYPQHRINIIDTPGHVDFTIEVERSLRVLDGAIAVFCAVGGVEPQSETVWRQATKYEVPRMAFVNKMDRAGANFGRVVEQIRTRLKATPVPLQLPIGAEDEFKGVVDLVRMKAIYWNEEDMGVTYEQTDVPAELADEAAEAREFLVEAAAEADEELMDKYLEGGELTVEEINRGLRARTLANEIVPAFCGSAFKNKGVQALLDGVIEYLPSPVDVPAIEGELDDADGTVATRKPGDDQPFAALAFKIATDPYVGTLTFFRVYSGVVQTGDTVFNPVKGKKERLGRIVQMHANSREEIKEVRAGDIAAAVGLKDVTTGDTLCDINNKITLERMEFPDPVISVAVEPKTKGDQEKMGMALGKLAQEDPSFQVRTDEESGQTIISGMGELHLDIIVDRLKREFKVEANVGAPQVAYRETIRKTVEQEGKFVRQSGGRGQYGHVHLRISPQERNAGYEFVNSIVGGVVPKEYIPSVDKGAYEALENGILAGFPAIDVKVELYDGSYHDVDSSEAAFKIAGSMAMKEGFMKADPVLLEPIMRVEVVTPEEYMGDVMGDLNRRRGTVQGMEDGPSGKIIRAQVPLKEMFGYATDLRSATQGRASYVMFFDEYQEAPASIADEIIKKAS
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCGN_SALEP
Sequence: MADTLMSDTPFWQRKTLDEMTDAEWESLCDGCGQCCLHKLMDEDTDEIYFTNVACRQLNIKTCQCRHYERRFEFEPDCIKLTRENLPDFEWLPMTCAYRLLAEGKPLPTWHPLLTGSKAAMHGERISVRHIAVKESEVRDWQDHILNKPSWAE
What are the official names of this protein?
UPF0260 protein YcgN.
What is the protein family that this protein belongs to?
Belongs to the UPF0260 family.
Protein: 3SX2_MICFR
Sequence: LICYVSKDGETATCPPGQKCEKYAVSASHTGHWFYMYDCTSTCHIGPYNVCCSTDLCNR
What is the function of this protein?
Neurotoxin.  Blocks muscular nicotinic acetylcholine receptors (nAChR).
What are the official names of this protein?
Frontoxin II, FTx II, Three-finger toxin, 3FTx.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: VE1_HPV19
Sequence: MAESKGSTSKEGFGDWCILEAECSDVENDLEKLFDEDTDSDISDLLDDNDLEQGNSRELFHQQECQESEEHLQKLKRKYLSPKAVAQLSPRFESISLSPQQKSKRRLFAEQDSGLELTLTNEAEDVSSEVEVPALDSQPVAGEQSGDIDIHFTALLRANNNRAILMAKFKEAFGVGFYDLTRQFKSYKTCCNAWVISVYAVHDDLLESSKQLLQQHCDYVWIRQTAAMSLFLLCFKVGKNRGTVHKLMMSMLNVHEKQILSEPPKLRNTAAALFWYKGCMGSGGFTYGPYPDWIAQQTILGHQNAEASSFDLSEMIQWAFDNNHMDESDIAYQYAKLAPENSNAVAWLAHNNQARFVRECAAMVRFYKKGQMKEMSMSEWIYARIHEVDGEGHWSTIAKFLRYQQVNFIMFLAALKDLLHAVPKRNCILIYGPPNTGKSAFTMSLIRVLKGRVISFVNSKSQFWLQPLSECKIALLDDVTDPCWIYMDTYLRNGLDGHVVSLDCKHKAPIQTKFPALLLTSNINVHNEVNYRYLHSRIQGFEFPNPFPMKADNTPQFELTDQSWKSFFTRLWQQLELSDHEEEGENGESQRTFQCSTRSANEHL
What is the function of this protein?
ATP-dependent DNA helicase required for initiation of viral DNA replication.  It forms a complex with the viral E2 protein.  The E1-E2 complex binds to the replication origin which contains binding sites for both proteins.  During the initial step, a dimer of E1 interacts with a dimer of protein E2 leading to a complex that binds the viral origin of replication with high specificity.  Then, a second dimer of E1 displaces the E2 dimer in an ATP-dependent manner to form the E1 tetramer.  Following this, two E1 monomers are added to each half of the site, which results in the formation of two E1 trimers on the viral ori.  Subsequently, two hexamers will be created.  The double hexamer acts as a bi-directional helicase machinery and unwinds the viral DNA and then recruits the host DNA polymerase to start replication.
What are the official names of this protein?
Replication protein E1, ATP-dependent helicase E1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E1 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: Y3406_METJA
Sequence: MNIDDYIEKLEIQKEGFFYKCPYCNYTNADVKAIKKHIKSKHYDIIAKEVENLNKQNKPQRKPMKKQPKKKDDDYKDYMLLFAHKKKCKIYLDNGMIVEGTVKAKDRFNIMVLDAKVDDKEVERIIIQKGHIVALIPLEE
What are the official names of this protein?
Uncharacterized protein MJECS06.
What is the protein family that this protein belongs to?
To M.jannaschii MJECL27.
Protein: H2B1_CANAL
Sequence: MAPKAEKKPASKAPAEKKPAAKKTASTDGAKKRTKARKETYSSYIYKVLKQTHPDTGISQKAMSIMNSFVNDIFERIATEASKLAAYNKKSTISAREIQTAVRLILPGELAKHAVSEGTRAVTKYSSASS
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.1.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: Y7I8_ENCCU
Sequence: MIGRMVGLEPSSRSGVLEECRECRAIVMKGDGVQTPLHKGDSILGGEGACLMRYAAWTLISAVDVVYCSLETRESVSLTFNPDGQVIVVPFMFKGYNIAALPTTKFGDLKKDTKQIENVVSFLRSDICYAVWEFLVSSVQYKDDDRFERLFDERMRGYLRNISEGTSKVYMRGNKTFSELLEMVCGRMLECSGRVAGGGHSKIWKRCHENA
What are the official names of this protein?
UPF0329 protein ECU07_1880/ECU10_0020.
What is the protein family that this protein belongs to?
Belongs to the UPF0329 family.
Protein: HYPA_ECOLI
Sequence: MHEITLCQRALELIEQQAAKHGAKRVTGVWLKIGAFSCVETSSLAFCFDLVCRGSVAEGCKLHLEEQEAECWCETCQQYVTLLTQRVRRCPQCHGDMLQIVADDGLQIRRIEIDQE
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase (PubMed:12081959, PubMed:15995183).  Mediates transfer of nickel, but not zinc, from the low-affinity metal-binding site in the GTPase domain of HypB to HypA (PubMed:23899293, PubMed:27951644).  HypA is involved in maturation of hydrogenase 3.  It may partially substitute for the function of HybF and vice versa (PubMed:12081959).  May act as a scaffold for assembly of the nickel insertion proteins with the hydrogenase precursor protein after delivery of the iron center (PubMed:22016389).
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: YMFI_BACSU
Sequence: MNKTALITGASGGIGKSISETLAARGYNLLLHYNTNQNAAAELAEKLSQMFGVNAEILQADLSAQDGADKLTSSIVQPIDAIVLNSGRSHFGLITDVDNATVQEMVQLHVASPYMLTRNLLPGMIRNKSGAIVAVSSIWGETGASCEVLYSMAKGAQHSFVKGLAKELAPSGIRVNAVAPGAVDTNMMNQFTPAEKEEIADEIPIGRLARPQEIADATAFLLSEKASYITGQILSVNGGWHC
What are the official names of this protein?
Uncharacterized oxidoreductase YmfI.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: CECA1_AEDAL
Sequence: MNFTKLFAIVLLAALVLLGQTEAGGLKKLGKKLEGVGKRVFKASEKALPVAVGIKALGK
What is the function of this protein?
Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria.
What are the official names of this protein?
Cecropin-A1, AalCecA, Cecropin-A.
What is the protein family that this protein belongs to?
Belongs to the cecropin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRY1_GADMO
Sequence: MKSLIFVLLLGAVFAEEDKIVGGYECTKHSQAHQVSLNSGYHFCGGSLVSKDWVVSAAHCYKSVLRVRLGEHHIRVNEGTEQYISSSSVIRHPNYSSYNINNDIMLIKLTKPATLNQYVHAVALPTECAADATMCTVSGWGNTMSSVADGDKLQCLSLPILSHADCANSYPGMITQSMFCAGYLEGGKDSCQGDSGGPVVCNGVLQGVVSWGYGCAERDHPGVYAKVCVLSGWVRDTMANY
What are the official names of this protein?
Trypsin-1, Trypsin I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: Y1248_METJA
Sequence: MKMEVIEKLSELSGIDKKSLRRILIILEFSLRKKDGSPTSFAEKFNIKSFGDLYNYIRDVKSNLKRDHEIEGFNGLTEMWKSVAPRAQYWIMDTFGEENPRDALFSASVFTMRTFGIMLDNLLLLKKIIKTLDEYQKEVTEYVSAQKFEAEDLE
What are the official names of this protein?
Uncharacterized protein MJ1248.
Protein: CSHB_STAA8
Sequence: MAKHPFEQFNLESSLIDAVKDLNFEKPTEIQNRIIPRILKRTNLIGQSQTGTGKSHAFLLPLMQLIDSEIKEPQAIVVAPTRELAQQLYDAANHLSQFKAGVSVKVFIGGTDIEKDRQRCNAQPQLIIGTPTRINDLAKTGHLHVHLASYLVIDEADLMIDLGLIEDVDYIAARLEDNANIAVFSATIPQQLQPFLNKYLSHPEYVAVDSKKQNKKNIEFYLIPTKGAAKVEKTLNLIDILNPYLCIIFCNSRDNANDLARSLNEAGIKVGMIHGGLTPRERKQQMKRIRNLEFQYVIASDLASRGIDIEGVSHVINFDVPNDIDFFTHRVGRTGRGNYKGVAITLYSPDEEHNISLIEDRGFVFNTVDIKDGELKEVKAHNQRQARMRKDDHLTNQVKNKVRSKIKNKVKPGYKKKFKQEVEKMKRQERKQFSKQQNRQKRKQNKKG
What is the function of this protein?
Probable DEAD-box RNA helicase.  May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures.
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase CshB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. CshB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TXNIP_PIG
Sequence: MVMFKKIKSFEVVFNDPEKVYGCGEKVAGRVIVEVCEVTRIKAVRILACGVAKVLWMQGSQQCKQTLDYLRYEDTLLLDDHPTGENEMVIMRPGNKYEYKFGFELPQGPLGTSFKGKYGCVDYWVKAFLDRPSQPTQETKKHFEVMDLVDVNTPDLMAPVSAKKEKKVSCMFIPDGRVSVSARIDRKGFCEGDEINIHADFENTCSRIVVPKAAIVARHTYLANGQTKVLTQKLSSVRGNHIISGTCASWRGKSLRVQKIRPSILGCNILRVEYFLLIYVSVPGSKKVILDLPLVIGSRSGLSSRTSSMASRTSSEMSWVDLNIPDTPEAPPCYMDIIPEDHRLESPTTPLLDDTDGSQDSPIFMYAPEFKFMPPPTYSEVDPCILNNNVQ
What is the function of this protein?
May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability.  Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm.  Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1) (By similarity).  Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest.  Required for the maturation of natural killer cells.  Acts as a suppressor of tumor cell growth (By similarity).
What are the official names of this protein?
Thioredoxin-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the arrestin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1098_METJA
Sequence: MYEKYIVEGLSDREIAYLIGCGKATVVRARQKHGIYREDVKMCDDYTLDNISEDLRTFIDGLLLGDACITEKGNLLITQNKRYDWLEYVKHRFQQFGLNVYFHCYKYKRRTSEVIADLYVLSTSRYELFRQLRERWYPDGIKRIPNDLVINDEGLAQWYLGDGSLTKQKNGYKLELSTHGFTLDENKFLQQKLKLLYGFDFRISKKHQYRYLRLFKSKQVHAFCSIVEPFIPPSYRNKVRCLHDYQWLKSWDVI
What are the official names of this protein?
Uncharacterized protein MJ1098.
Protein: TRPC2_MOUSE
Sequence: MLMSRTDSKSGKNRSGVRMFKDGDFLTPASGESWDRLRLTCSQPFTRHQSFGLAFLRVRSSLGSLADPVVDPSAPGSSGLNQNSTDVLESDPRPWLTNPSIRRTFFPDPQTSTKEISELKGMLKQLQPGPLGRAARMVLSAARKAPPASVVSPNNSHGEPGPSRAESAEPRAEEPNRKTAVGRRKRRKVQEPRRSLSNSSSQPNRRTGRTRQRQHRPQTKSDDGGVQAAGQCPICAGFFSIETLPQHAATCGESPPPQPASPASLSSSESVLRRHHVALTPVPLVPKPQPNWTEIVNKKLKFPPTLLRAIQEGQLGLVQQLLESSSDASGAGPGGPLRNVEESEDRSWREALNLAIRLGHEVITDVLLANVKFDFRQIHEALLVAVDTNQPAVVRRLLARLEREKGRKVDTKSFSLAFFDSSIDGSRFAPGVTPLTLACQKDLYEIAQLLMDQGHTIARPHPVSCACLECSNARRYDLLKFSLSRINTYRGIASRAHLSLASEDAMLAAFQLSRELRRLARKEPEFKPQYIALESLCQDYGFELLGMCRNQSEVTAVLNDLGEDSETEPEAEGLGQAFEEGIPNLARLRLAVNYNQKQFVAHPICQQVLSSIWCGNLAGWRGSTTIWKLFVAFLIFLTMPFLCIGYWLAPKSQLGRLLKIPVLKFLLHSASYLWFLIFLLGESLVMETQLSTFKGRSQSVWETSLHMIWVTGFLWFECKEVWIEGLRSYLLDWWNFLDVVILSLYLASFALRLLLAGLAYMHCRDASDSTTCRYFTTAERSEWRTEDPQFLAEVLFAVTSMLSFTRLAYILPAHESLGTLQISIGKMIDDMIRFMFILMIILTAFLCGLNNIYVPYQESEKLGNFNETFQFLFWTMFGMEEHTVVDMPQFLVPEFVGRAMYGIFTIVMVIVLLNMLIAMITNSFQKIEDDADVEWKFARSKLYLSYFREGLTLPVPFNILPSPKAAFYLVRRIFRFLCCGSSCCKAKKSDYPPIGTFTNPGARAGSAGEGERVSYRLRVIKALVQRYIETARREFEETRRKDLGNRLTELTKTVSRLQSEVASVQKNLAAGGAPRPPDGASILSRYITRVRNSFQNLGPPTSDTPAELTMPGIVETEVSLGDGLDGTGEAGAPAPGEPGSSSSAHVLVHREQEAEGSGDLLLEGDLETKGES
What is the function of this protein?
Thought to form a receptor-activated non-selective calcium permeant cation channel.  Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors.  May also be activated by intracellular calcium store depletion.  Plays a role in mediating responsivity to pheromones that elicit aggressive and mating behaviors.  Required for response to the Esp1 pheromone which enhances female sexual receptive behavior and to the Esp22 pheromone which inhibits adult male mating behavior.
What are the official names of this protein?
Short transient receptor potential channel 2, TrpC2, Transient receptor protein 2, TRP-2, mTrp2.
What is the protein family that this protein belongs to?
Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC2 sub-subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ARC2A_ARATH
Sequence: MILLQSHSRFLLQTLLTRAQNLDKAVELDYQWIEFDDVRYHVQVTMKNPNLLLLSVSLPNPPPEAMSFDGLPLGAIEAIKTTYGTGFQILDPPRDGFSLTLKLNFSKVRPDEELLTKLASIREVVMGAPLKIIFKHLASRTVAPELDRLVAIMHRPNETFFLVPQADKVTVAFPMRFKDSVDTILATSFLKEFVEARRAAALNTAPSCSWSPTAPQELEGAPKETLSANAGFVTFVIFPRHVEGKKLDRTVWNLSTFHAYVSYHVKFSEGFMHTRMRRRVESMIQALDQAKPLEKTRSMNNKSFKRLGLNEVNHTNSK
What is the function of this protein?
Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.  Seems to contact the mother actin filament (By similarity).  Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.
What are the official names of this protein?
Actin-related protein 2/3 complex subunit 2A, Actin-related protein C2A, Arp2/3 complex 34 kDa subunit, p34-ARC, Protein DISTORTED TRICHOMES 2.
What is the protein family that this protein belongs to?
Belongs to the ARPC2 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection.
Protein: EFG_GRAFK
Sequence: MAQRDLKFTRNIGIAAHIDAGKTTTTERILYYTGISHKIGEVHDGAATMDWMEQEQERGITITSAATHCKWMYRDQEFTVNIIDTPGHVDFTVEVERSLRVLDGVVALFSAVDGVEPQSETVWRQADKYRVPRLGFVNKMDRQGADFFNVCRQVREMLGGNPVPLQVPIGDEIDFKGVVDLISKKAIIWNDEDHGMTYDTIEIPEELLDDVNKYRAELVEAVAEYDEALMEKFFEDESSITEDEIIAALRAATIDMSIIPMMCGSAFKNKGVQAMLDAVMRYLPSPADVEAIEGTNPDTGEEESRKPHVDSPFAALAFKIATDPFVGRLAFFRAYSGTLDAGSYVLNVRSGKKERISRIYQMHSNKQEPIDSIEAGDIGAAVGFKDIKTGDTLTDMKHPIVLESMSFPAPVIGIAVEPKTKADVEKMGMALGKLAEEDPTFTVKTDENSGQTIISGMGELHLEIIIDRMKREFKVEVNVGEPQVEYKETITKSADHREVYKKQSGGRGKFADIVFEMGPIDEDFEGTGLQFVDVIKGGRIPKEFVPSVEKGFKEAMKNGPLAGFTMDSLKVTLKDGSFHPVDSDQLSFELAAKMGYKDAAKKAGAVILEPIMKVEVVTPEENMGDIVGDLNRRRGQVNNMSDRSGAKVIKAEVPLSEMFGYVTTLRTLSSGRATSTMEFSHYAETPSNISEEVIKAAKGAANE
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRHO_STAA9
Sequence: MNYQVLLYYKYTTIDDPEQFAQDHLAFCKAHHLKGRILVSTEGINGTLSGTKEETEQYMAHMHADERFKDMVFKIDEAEGHAFKKMHVRPRKEIVALDLEDDVDPRHTTGQYLSPVEFRKALEDDDTVIIDARNDYEFDLGHFRGAIRPDITRFRDLPDWIKENKALFTDKKVVTYCTGGIRCEKFSGWLLKEGFEDVAQLHGGIATYGKDPETKGQYWDGKMYVFDDRISVDINQVEKTIIGKDWFDGKPCERYINCANPECNKQILVSEENETKYLGACSYECAKHERNRYVQANNISDNEWQQRLTNFDDLHQHA
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: HEXR_ECOLI
Sequence: MNMLEKIQSQLEHLSKSERKVAEVILASPDNAIHSSIAAMALEANVSEPTVNRFCRSMDTRGFPDFKLHLAQSLANGTPYVNRNVNEDDSVESYTGKIFESAMATLDHVRHSLDKSAINRAVDLLTQAKKIAFFGLGSSAAVAHDAMNKFFRFNVPVVYSDDIVLQRMSCMNCSDGDVVVLISHTGRTKNLVELAQLARENDAMVIALTSAGTPLAREATLAITLDVPEDTDIYMPMVSRLAQLTVIDVLATGFTLRRGAKFRDNLKRVKEALKESRFDKQLLNLSDDR
What is the function of this protein?
Represses the expression of the hex regulon (zwf, eda, glp and gap).
What are the official names of this protein?
HTH-type transcriptional regulator HexR, Hex regulon repressor.