PharMolix/UniProtQA huggingface dataset:
Protein: ATAT1_CAEBR
Sequence: MQVNADLRPILGPQLVRLDPMRIKQLQDPQVYDAIDSLAKLSAHCLQLRTPLTTCEKLINSDSTLYLSWKYDEEEKVSRLLGFAKVGRKKLFLYDAQMQTYEGEVLCLLDFYVHFSTQRQGVGKQILDYMFSQEHAEPYQLALDNPSVTLLGFMSQKYGMNRPVWQNTNFVVFDELFQSLSAENGVGTVDFQSCKYRIFNSEKSPPDGWRRPMTPRRLGTGMTDTRWLQHAVSGHQSKGNAMAAPVDADMTPQGALSNRAHQAKARKAHILSSKPLW
What is the function of this protein?
Specifically acetylates 'Lys-40' in alpha-tubulin/mec-12 on the lumenal side of microtubules.  Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity.  Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer.  Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules.  Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released.  Required for the maintenance of touch receptor neurons and possibly other type of neurons involved in locomotion.
What are the official names of this protein?
Alpha-tubulin N-acetyltransferase 1, Alpha-TAT 1, TAT 1, Mechanosensory abnormality protein 17.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase ATAT1 family.
Protein: PTMA_STRMU
Sequence: MEFQKDLIKLNQHFPDKEAAIRFCGQLLADGGYVEPAYIDAMIQRDKELSVYMGNFIAIPHGTDDAKKDVLKSGITVVQVPDGVNFGTEDDPQVATVLFGIAGIGDEHLQIIQNISIFCADVDNVVKLADAQTEDEVVKLLSQVN
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II CmtAB PTS system is involved in D-mannitol transport.
What are the official names of this protein?
Mannitol-specific phosphotransferase enzyme IIA component, EIIA, EIII, PTS system mannitol-specific EIIA component.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YEAL_ECOBW
Sequence: MFDVTLLILLGLAALGFISHNTTVAVSILVLIIVRVTPLSTFFPWIEKQGLSIGIIILTIGVMAPIASGTLPPSTLIHSFLNWKSLVAIAVGVIVSWLGGRGVTLMGSQPQLVAGLLVGTVLGVALFRGVPVGPLIAAGLVSLIVGKQ
What are the official names of this protein?
UPF0756 membrane protein YeaL.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CETN2_TOXGM
Sequence: MQRGALRGASPTARRRLVDRPGLTEDEIEEIREAFNLFDTDGSGMIDPKELKAAMQSLGFETKNPTIYQMIADLDRDSGGPIDFEEFLDAITAKLGDKESREGIQKIFSLFDDDRTGTITLKNLKRVAKELGETMSEDELREMLERADSNGDGEISFEDFYAIMTKKTFP
What is the function of this protein?
In tachyzoites, plays an essential role in microneme secretion that ensures parasite motility and attachment to, invasion of and egress from host cells (PubMed:31182647, PubMed:31206964).  Also involved in the architecture of the peripheral annuli where it appears to regulate the localization of PAP2 (PubMed:31206964).  In association with the myosin motor MyoJ, involved in the constriction of the basal complex at the end of daughter cell division in an actin-dependent manner; the basal complex is a cytoskeletal structure formed at the tachyzoite basal pole during daughter cell formation (PubMed:28593938).  May be involved in parasite replication (PubMed:31182647).
What are the official names of this protein?
Centrin-2, TgCEN2.
What is the protein family that this protein belongs to?
Belongs to the centrin family.
Protein: RL8B_YEAST
Sequence: MAPGKKVAPAPFGAKSTKSNKAKNPLTHSTPKNFGIGQAVQPKRNLSRYVKWPEYVRLQRQKKILSIRLKVPPTIAQFQYTLDRNTAAETFKLFNKYRPETAAEKKERLTKEAAAIAEGKSKQDASPKPYAVKYGLNHVVSLIENKKAKLVLIANDVDPIELVVFLPALCKKMGVPYAIIKGKARLGTLVNQKTSAVAALTEVRAEDEAALAKLVSTIDANFADKYDEVKKHWGGGILGNKAQAKMDKRAKTSDSA
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L8-B, L4, L4-1, Large ribosomal subunit protein eL8-B, RP6, YL5.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_CROCR
Sequence: MTNIRKSHPLIKIVNESFIDLPTPSNISAWWNFGSLLGICLILQILTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLYMHIGRGMYYGSYTLPETWNIGILLLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWVWGGSSVDKATLTRFFALHFILPFIILAVATVHLLFLHETGSNNPSGMTSDTDKIPFHPYYTTKDILGLLLLILMLLLLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALTLSILILAMVPLLHTSKQRGMTFRPISQCLFWLLVVDLLTLTWIGGQPVEHPYTIIGQLASIMYFSIILILMPISGIIENHLLNW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RS17_HAEIN
Sequence: MTDKIRSVQGKVVSDKMEKSFVVAIERKVKHPLYGKFIRRTTKLHVHDENNEAKVGDTVEIRECRPLSKTKSWTLVRVVEKAVIA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: Y474_CHLTR
Sequence: MGIEGRGSGAMQSKKTIKWLKQALVLSSIVNILLLLLIYSTVFRKDIYKLRVFPGNLIAKSSRIGKIPEDILERLENASFADLLALLQEERMVFGHPLKSWALGVSIQKYFVDIAPMLTHPLTFIRLKSPERTWLLPDINDQEFTRICQYLLTERFPFSSRGFFRIMVRDCEAGMVDEDVLYRFCHLPEFLYVRSLLFGAEIEAASVASLARMIIQGGEDLFFSLCCLENRQTAISDHQRRCFLKAYVDRQEPLAALLLLVHDADWVLHEFSDSDLQSFIQLLPREAHYTKKFLGCVAQSCRLGILLEG
What are the official names of this protein?
Uncharacterized protein CT_474.
What is the protein family that this protein belongs to?
Belongs to the chlamydial CPn_0593/CT_474/TC_0759 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: AZOR3_BACCR
Sequence: MATVLFVKANNRPAEQAVSVKLYEAFLANYKEANPNDTVVELDLYKEELPYVGVDMINGTFKVGKGFDLTEEEAKAVAVADKYLNQFLEADKVVFGFPLWNLTIPAVLHTYIDYLNRAGKTFKYTPEGPVGLIGDKKIALLNARGGVYSEGPAAEVEMAVKYVASMMGFFGATNMETVVIEGHNQFPDKAEEIIAAGLEEAAKVASKF
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase 3, Azo-dye reductase 3, FMN-dependent NADH-azo compound oxidoreductase 3, FMN-dependent NADH-azoreductase 3.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: MURB_AMOA5
Sequence: MDLQENIPLQSLNTFGIAATARYYSLVKSQAMLKQLLNNSSLHSLLKLTIGGGSNILFVKDFDGWVIHMDIKGIEKLGEDNNHIWLHVGAGVNWHSLVLYCIEKGYAGIENLSLIPGTVGAAPIQNIGAYGVEFSEVFESLEALEISTGLIKKFNKEACAFSYRDSIFKSSLKGQYIILQVTLRLNKQPTFQTNYGAIQEVLASMKPRTLSIKAISDAVIYIRQQKLPNPAYIGNAGSFFKNPIIDQAKATLLRNKYPNIPVHILANGYAKLPAAWLIEQSGWKGYRHDAVGVHLHQPLVIVNYGGATGKAVYKLAQAIQASVAENFSVMLEPEVNIIQ
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_BEII9
Sequence: MSDLDTLLMETLAQVAFAADEGELENVRVGALGKKGTISALLATLGKMSPDERKVQGAAINALKDKVNEALAERRLILKEQKLEARLAAEIIDVTLPVLPRPEELGRIHPITQVMDELAAIFAEMGFAIAEGPDIETDDYNFTKLNFPPDHPARDMHDTFFFEPDAQGQRKVLRTHTSPVQVRTMLTQKPPIRVICPGRTYRCDSDQTHTPMFHQVEGLVIDKSAHLGHLKWILEEFCKAFFEVPDVKMRFRPSYFPFTEPSMEVDIQCSRKGGEIRFGEGEDWLEILGCGMVHPNVLRNCGLDPDVYQGFAWGMGIDRIAMLKYGMPDLRAFFEADIRWLNHYGFRPLDMPSLLSGLSS
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNC_NEIMB
Sequence: MKDDVLKQQAHAAIQKKLGYAFRDISLLRQALTHRSHHAKHNERFEFVGDSILNYTVARMLFDAFPKLTEGELSRLRASLVNEGVLAEMAAEMNVGDGLYLGAGELKSGGFRRPSILADAMEAMFAAVSFDADFNTAEKVVRHLFADRVRRADFQNQAKDGKTALQEALQARRFALPKYRIEEQIGYANDSMFVISCDLGELGFVCRAKGTSRKAAEQEAAKEALKWLEEKLPLKRKKK
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUT_BURP6
Sequence: MKLDLKILDARMRDYLPKYATTGSAGLDLRACLDAPVTLKPGDTALVPTGLAIHLADPGYAALILPRSGLGHKHGIVLGNLVGLIDSDYQGELMISTWNRGQTEFALNPFERLAQLVIVPVVQARFNLVDDFAQSERGAGGFGSTGRG
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: RL19_PELPB
Sequence: MDQLIKLVEATQAVTDFPEINPGDTVKIQLKVIEGEKERLQAFEGVVISDRGAGGNKTITVRKISHGVGVERIIPVNSPNIESVTVVKHGKARRAKLFYLRKRTGKAALKVKERKMAERV
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: RL33_SINFN
Sequence: MAKATTIKIKLLSTADTGYFYVTTKNSRTMTEKMTKTKYDPVVKKHVEFKETKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: LEUC_BUCUH
Sequence: MSKTLYQKIYDSHIVYEDKKNISVLYIDLHLIHEVTSPQAFDSLRNKKRKVRQPEKTFATMDHNVSTQKRDINASGSMAKKQMQQLIRNCDEFNISLYDINNPNQGIVHVIAPEKGMTLPGMIIVCGDSHTSTHGAFGALSFGIGTSEVEHVLATQTLKQQCFKNMKVEIVGDIPKFVTAKDIILFIIRRLGSSGGSGYVIEFCGNVIEKMSMEERMTVCNMAIEMGAKSGIIAPDETTYAYLKNKIYSPSGACWEXSISYWKTLKSDKDAFFDKCFTIDISNLAPQVTWGTSPDQVISINEKIPHYNEFNSITQKNSAKSALKYMGLNEGAYLTNISIDKVFIGSCTNARIEDLRSASKILKNRKISSNVKAIVVPGSGSVKQQAEREGLDKIFINSGFEWRLPGCSMCLGMNRDQLNIGERCASXSNRNFEGRQGRGGRT
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: PTN20_MOUSE
Sequence: MSSPRKVRGKTGRDNDEEEGNSGNLNLRNSLPSSSQKMTPTKPIFGNKMNSENVKPSHHLSFSDKYELVYPEPLESDTDETVWDVSDRSLRNRWNSMDSETAGPSKTVSPVLSGSSRLSKDTETSVSEKELTQLAQIRPLIFNSSARSAMRDCLNTLQKKEELDIIREFLELEQMTLPDDFNSGNTLQNRDKNRYRDILPYDSTRVPLGKNKDYINASYIRIVNHEEEYFYIATQGPLPETIEDFWQMVLENNCNVIAMITREIECGVIKCYSYWPISLKEPLEFEHFSVFLETFHVTQYFTVRVFQIVKKSTGKSQCVKHLQFTKWPDHGTPASADFFIKYVRYVRKSHITGPLLVHCSAGVGRTGVFICVDVVFSAIEKNYSFDIMNIVTQMRKQRCGMIQTKEQYQFCYEIVLEVLQNLLALY
What is the function of this protein?
Tyrosine-protein phosphatase targeted to sites of actin polymerization in response of varied extracellular stimuli.  Has tyrosine phosphatase activity towards various tyrosyl phosphorylated substrates.
What are the official names of this protein?
Tyrosine-protein phosphatase non-receptor type 20, Testis-specific tyrosine phosphatase.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Colocalizes with the microtubule-organizing center and intracellular membrane compartments.
Protein: SLX1_VANPO
Sequence: MMNSSQFSDSQTTSLHRIPTFYCCYLLQSINKKQSFYIGSTPNPVRRLRQHNGNLSNGGAYRTKREGTRPWEMVLVVYGFTSKIAALQFEHAWQHGYKTHYIPMDDRIMKNANSGRTVHHKLGLVRQLLANVYFRHMNLKVHFFSMPILDVWNLNKFNIKMGSNEISVDVSQVSQETKTNLEQASDDDDDNGACSRDERNLQLVTELYDNTVTKENEIKEIIKDILVLGERNCNLCGQCYDYTSEDDTMKMHIFICPNSTCHYEAHLNCLYEKFIEEESGIDSKNILLPNFCMCPGCLDEMSWSDFVKISTMIKNSFSN
What is the function of this protein?
Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination.  Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
What are the official names of this protein?
Structure-specific endonuclease subunit SLX1.
What is the protein family that this protein belongs to?
Belongs to the SLX1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: BTBD9_RAT
Sequence: MSNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQYFRALLYGGMRESQPEAEIPLQDTTAEAFTMLLRYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLASDGFLSLSKTALLNIVLRDSFAAPEKDIFLALLNWCKHNAKENHAEIMQAVRLPLMSLTELLNVVRPSGLLSPDAILDAIKVRSESRDMDLNYRGMLIPEENIATMKYGAQVVKGELKSALLDGDTQNYDLDHGFSRHPIDDDCRSGIEIKLGQPSIINHIRLLLWDRDSRSYSYFIEVSMDELDWIRVIDHSHYLCRSWQKLYFPARVCRYIRIVGTHNTVNKIFHIVAFECMFTNKAFTLEKGLIAPMENVATIADCASVIEGVSRSRNALLNGDTKNYDWDSGYTCHQLGSGAIVVQLAQPYMIGSIRLLLWDCDDRSYSYYVEVSTNQQQWTMVADRTKVSCKSWQSVTFERQPASFIRIVGTHNTANEVFHCVHFECPEQQSTQKEDSSEEPGTGDLSTPSQQLDPHAPRAPSASSLPPSPGPNLHSPNQQNQ
What are the official names of this protein?
BTB/POZ domain-containing protein 9.
Protein: PRG4_HUMAN
Sequence: MAWKTLPIYLLLLLSVFVIQQVSSQDLSSCAGRCGEGYSRDATCNCDYNCQHYMECCPDFKRVCTAELSCKGRCFESFERGRECDCDAQCKKYDKCCPDYESFCAEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTSDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDETNICNGKPVDGLTTLRNGTLVAFRGHYFWMLSPFSPPSPARRITEVWGIPSPIDTVFTRCNCEGKTFFFKDSQYWRFTNDIKDAGYPKPIFKGFGGLTGQIVAALSTAKYKNWPESVYFFKRGGSIQQYIYKQEPVQKCPGRRPALNYPVYGETTQVRRRRFERAIGPSQTHTIRIQYSPARLAYQDKGVLHNEVKVSILWRGLPNVVTSAISLPNIRKPDGYDYYAFSKDQYYNIDVPSRTARAITTRSGQTLSKVWYNCP
What is the function of this protein?
Isoform F plays a role as a growth factor acting on the primitive cells of both hematopoietic and endothelial cell lineages.
What are the official names of this protein?
Proteoglycan 4, Lubricin, Megakaryocyte-stimulating factor, Superficial zone proteoglycan.
What are the subcellular locations of this protein?
Secreted.
Protein: FMT_RUMCH
Sequence: MKIIFMGTPEFAVPSLEMLINEGYNVIAVVTQPDKPKGRGKKLAAPPVKEFALEHGIKVLQPAKIKTPEFVEQIRELGPDLLITAAYGKIISKDMLDVPPLGCINVHGSLLPAYRGAAPIHWSIINGEKVTGITTMFTDVGLDTGDMLLKRELEISSDMTAGELHDEMAILGAEVLKDTLIHLKNGTLVRSPQDDALSSYAPIITKEVGLIDWNKTVQQVHNLVRGTNPWPGAFTFINESKMRVWKTCIVDFGNSQEHCPGEIVSVDDKGILVKCCDGYIMIKELQFDSSKRMKVRDYIRGNKIDTGEKLGK
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: PTH_PELPD
Sequence: MSMHIIAGLGNPGSHYQWTRHNAGFLFLDRLAHLENVSITRKSFSGLAGEWSRANCRHILLKPQTFMNLSGRSVMQALQFYKLPLSQAIVVHDDLDLPFGTVRLKQGGGHGGHNGLRSIMEQLGKGDFIRLRVGIGRPLHGDTVNYVLGSMPPEQMELLPRILDGGLEMLEMLLDQGLPKAMSLFNNRNFLEK
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TFDB_DELAC
Sequence: MNEKATVIETDVLVVGSGPAGAASTLLLATYGVKTLCVSKYATTSRTPRSHITNQRTMEVMRDLGLELECEAMASPAELMGENVYCTSLVGDELGRVLTWGTHPQRRADYELASPTHMCDLPQNLLEPIMINHAARRGADVRFHTEFVSLKQDETGVTATVRDHLLDRQYDIRAKYLIGADGANSQVVDQVGLPMEGKMGVSGSINVVFEADLTKYVGHRPSVLYWVIQPGSSVGGLGIGVIRMVRPWNKWLCIWGYDIAGGPPDLNEAHARQIVHSLLGDSTIPVKIESTSTWTVNDMYATRLFDNRVFCMGDAVHRHPPTNGLGSNTSIQDAFNLCWKLSHVLQGKAGPELLATYNEERAPVARQVVQRANKSLGDFPPILAALGLFDTKDPEQMQRNIARLKEQSPEAQEQRAALRAAIDGTQYVYNAHGVEMNQRYQSAAIVPDGTPDPGFRRDSELYHAHSGRPGAPVPHVWVTRHGRRVSTLDLCGKGRFSLLSGIAGSPWVEAAVHAAESLGIDLDVHIIGPGQELEDLYGDFARVREIEESGALLVRPDNFICWRAMRWQEGSGDELRAALKRVLSVH
What is the function of this protein?
Transforms 2,4-dichlorophenol (2,4-DCP) into 3,5-dichlorocatechol.
What are the official names of this protein?
2,4-dichlorophenol 6-monooxygenase, 2,4-dichlorophenol hydroxylase, 2,4-DCP hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the PheA/TfdB FAD monooxygenase family.
Protein: ENO_LACDA
Sequence: MTKVVIENVHAREIFDSRGNPTVEVEVTLSNGVVGRAEVPSGASTGENEAVELRDGGSRLGGKGVMKAVNNVNTAINNELQGADPFNQPAIDKAMIELDGTPNKGKLGANAILGTSMATAVAAAKATHQPLYRYLGGTDLSMPQTFHNVINGGEHADNGIDIQEFMITPVKKTSFRDGFEKIVNTYHTLKKVLEEKGYETGLGDEGGFAPNMKDSEEALKALHEAIERAGYVPGEDIAIACDCAASYYYNKEDGKYHLEGKVLDGDQLAEYYDKLLAEFPELISMEDPYDENDTEGMVKFTQSHKDRLQIVLDDFICTNPRLLEKAIKEGAGNASLIKLNQIGTVTETLETIRISRKHGYNTMISHRSGETGDTFIADFAVATNGGQLKTGAPARSERVEKYNQLLRIEEQLGDGERLDFFPAQD
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: LEPA_FRAT1
Sequence: MKNIRNFSIIAHIDHGKSTLSDRFIQVCNGLSEREMKEQVLDSMDIERERGITIKAQSVTLDYTARDGQTYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAAQGVEAQTVANCYTAIEQNLEVIPILNKIDLPSAEPDRVAQEIEEIIGIDATGATTCSAKIGIGVEDVLETIVAKVPAPEGDVNAKLQALIIDSWFDNYLGVVSLVRVKNGTIKKGEKFKVMSTGVAYQVDRLGVFTPKMKDLDHLKAGEVGFIVAGIKDIHGAPVGDTLTHAHNPTDKPVPGFKKVQPQVYAGMFTISSDDYPDFREALEKLSLNDASLFFEPEVSQALGFGFRCGFLGMLHMEIIQERLEREYNLDLITSAPTVVYKAIKKDGEIIEVDNLSKLPEPGAIAEIQEPIVRANILVPKDYVGSVITICIEKRGVQVDLNYVGNQVSITYDLPMIEVVSDFFDTLKSVTKGYGSLDYELIRYEPANMVCLDVLINGDKVDALASIVHKDQAKYKGRELVERLKELIPRQMFEVAIQAAIGGTIVARSTVKALRKNVLAKCYGGDVSRKKKLLEKQKEGKKRMKNIGSVEIPQEAFLSVLKK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL14_ACIB5
Sequence: MIQTETMLDVADNSGARRVQCIKVLGGSHRRYASVGDIIKVTVKEAIPRARVKKGDVMNAVVVRTKFGIRRPDGSVIRFDDNAAVILNNNKAPIATRIFGPVTRELRTEQFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RL6_THEM4
Sequence: MSRIANKPIVIPNGVEVKVENNVFKVKGPKGELSQEFLPYIKIEVNENEIYVKPNLEFMKRKSDLKKMKMFTGTYWRLFNNMIIGVTQGFRKELEIIGIGYRAQLQGKKLVMNLGYAHPVEMEIPSDVAVEVPSPNRIVVSGIDKQRVGQVAADIRRWREPNVYSGKGIRYVGEVVRLKEGKKA
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: PPAC_BACP2
Sequence: MGKTLVFGHKNPDTDTICSAIAYADLKNKIGVEAEAVRLGEINGETQFALDFFKQEAPRFIETAANETKQVILVDHNEFQQSVSDIDQVQVTEVIDHHRIANFETSEPLYYRAEPVGCTATILNKMYKENQVKIEKEIAGLLLSAIISDSLLFKSPTCTQQDIDAAHELAEIAGVDPEVYGLDMLKAGADLSQKTVQELITIDAKEFALGNSKVEIAQVNTVDIAEVTARQTDIEAKINEVIAAKGLDLFVLVITDILENDSLALALGAEAAKVEKAFHVTLENNTALLKGVVSRKKQVVPALTDALS
What are the official names of this protein?
Probable manganese-dependent inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase class C family.
What are the subcellular locations of this protein?
Cytoplasm.