PharMolix/UniProtQA huggingface dataset:
Protein: VIBB_VIBC3
Sequence: MAIPKIASYPLPVSLPTNKVDWRIDASRAVLLIHDMQEYFVHYFDSQAEPIPSLIKHIQQLKAHAKQAGIPVVYTAQPANQDPAERALLSDFWGPGLSEETAIIAPLAPESGDVQLTKWRYSAFKKSPLLDWLRETGRDQLIITGVYAHIGILSTALDAFMFDIQPFVIGDGVADFSLSDHEFSLRYISGRTGAVKSTQQACLEIAAQHSKLTGLSLRTMQHDVAAALNLSVDEVDVQENLLFLGLDSIRAIQLLEKWKAQGADISFAQLMEHVTLQQWWQTIQANLHQPCSA
What is the function of this protein?
Involved in the biosynthesis of the catechol siderophore vibriobactin.  Vibriobactin is a chelating compound involved in transporting iron from the bacterial environment into the cell cytoplasm (By similarity).
What are the official names of this protein?
Vibriobactin-specific isochorismatase, 2,3 dihydro-2,3 dihydroxybenzoate synthase, Isochorismate lyase-ArCP.
What is the protein family that this protein belongs to?
Belongs to the isochorismatase family.
Protein: RS20_BORBR
Sequence: MANTAQARKRARQSVQRNKHNSSLRSMLRTAIKRVRQSIATGDKAAAGETLRKATSVIDSVADKNIIHKNKAARHKSRLAAAVKALA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: SYQ_RAT
Sequence: MATPDSLALFTGLGLSENKARETLKNAALSTQLREAATQAQQTLGSTIDKATGTLLYGLASRLRDTRRLSFLVGYIANKKIHTELQLSAALEYVRSHPLDPIDTKDFEQECGVGVVVTPEQIEEAVEATINRHRPQLLVERYRFSMGLLMGEARAALRWADGKMIKNEVDMQVLHLLGPKMEADLEKKPKVAKARLEETDRKTAKDVVENGEVAGQTLSLMEQLRGEALKFHKPGENYKTPGYVTTPHTMDLLKQHLEITGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAIYDMVTWLGYTPYKVTYASDYFDQLYAWAVELIRRGQAYVCHQRGEELKGHNPLPSPWRDRPIEESLLLFEAMRKGKFAEGEATLRMKLVMEDGKMDPVAYRVKYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPVQWEYGRLNLHYAVVSKRKILQLVAAGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVGVTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLEPLQVVITNFPAPKPLDIRVPNFPADETKGFHQVPFASTVFIERTDFKEESEPGYKRLAWGQPVGLRHTGYVIELQHVVRGSSGCVECLEVTCRRADAGEKPKAFIHWVSQPLVCEIRLYERLFQHKNPEDPVEVPGGFLSDLNPASLQVIKGALVDCSVALAKPFDKFQFERLGYFSVDPDSHQGQVVFNRTVTLKEDPGKV
What is the function of this protein?
Glutamine--tRNA ligase.  Plays a critical role in brain development.
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm.
Protein: SODM_ENTFA
Sequence: MTYTLPELPYAYDALEPYIDVETMHLHHDKHHNTYVTNLNAAIEKHPELGEKSVENLISDMNAIPEDIRTAVRNNGGGHANHTFFWEIMAPNAGGQPTGAIKEAIDETFGSFDEMKAAFKTAATGRFGSGWAWLVVNNGKLEITSTPNQDSPLMDGQTPVLGLDVWEHAYYLKYKNVRPDYIEAFWNVVNWDKVNELFAAAK
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Fe].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: COMD8_HUMAN
Sequence: MEPEEGTPLWRLQKLPAELGPQLLHKIIDGICGRAYPVYQDYHTVWESEEWMHVLEDIAKFFKAIVGKNLPDEEIFQQLNQLNSLHQETIMKCVKSRKDEIKQALSREIVAISSAQLQDFDWQVKLALSSDKIAALRMPLLSLHLDVKENGEVKPYSIEMSREELQNLIQSLEAANKVVLQLK
What is the function of this protein?
May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237).  May down-regulate activation of NF-kappa-B (PubMed:15799966).
What are the official names of this protein?
COMM domain-containing protein 8.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y378_METVS
Sequence: MIEEIIKKTEKGVLIDIEVTTNAKKNEIGKINKWRKRLEVKIKEQPIEGRANKAILKFLKEIFKTDVELNPVTTSPQKTVLISCDTKEYVVNILKREIKSV
What are the official names of this protein?
UPF0235 protein Mevan_0378.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: CLPB_STAAW
Sequence: MDINKMTYAVQSALQQAVELSQQHKLQNIEIEAILSAALNESESLYKSILERANIEVDQLNKAYEDKLNTYASVEGDNIQYGQYISQQANQLITKAESYMKEYEDEYISMEHILRSAMDIDQTTKHYINNKVEVIKEIIKKVRGGNHVTSQNPEVNYKALAKYGRDLVEEVRQGKMDPVIGRDEEIRNTIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPESLLDKTVFELDLSALVAGAKYRGEFEERLKAVLKEVKESDGRIILFIDEIHMLVGAGKTDGAMDAGNMLKPMLARGELHCIGATTLNEYREYIEKDSALERRFQKVAVSEPDVEDTISILRGLKERYEVYHGVRIQDRALVAAAELSDRYITDRFLPDKAIDLVDQACATIRTEMGSNPTELDQVNRRVMQLEIEESALKNESDNASKQRLQELQEELANEKEKQAALQSRVESEKEKIANLQEKRAQLDESRQALEDAQTNNNLEKAAELQYGTIPQLEKELRELEDNFQDEQGEDTDRMIREVVTDEEIGDIVSQWTGIPVSKLVETEREKLLHLSDILHKRVVGQDKAVDLVSDAVVRARAGIKDPNRPIGSFLFLGPTGVGKTELAKSLAASLFDSEKHMIRIDMSEYMEKHAVSRLIGAPPGYIGHDEGGQLTEAVRRNPYSVILLDEVEKAHTDVFNVLLQILDEGRLTDSKGRSVDFKNTIIIMTSNIGSQVLLENVKETGEITESTEKAVMTSLNAYFKPEILNRMDDIVLFKPLSIDDMSMIVDKILTQLNIRLLEQRISIEVSDDAKAWLGQEAYEPQYGARPLKRFVQRQIETPLARMMIKEGFPEGTTIKVNLNSDNNLTFNVEKIHE
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_PROMA
Sequence: MNIIFWGTPIFCVPILEKLLKSNHNVLAVITQPDRRRGRGNKVLPSPIKQKALEENLPIYTPVNITKEKDIQAKIKQYNADIFVVVAFGQILPKSVLKLPKYGCWNIHASLLPRWRGAAPIQWSILSGDSETGVGLMAMEEGLDTGAVLLEKKLKLKLLENAEQLSQRLKDLSCNLIIEGIEILEKVREQSQSLSKLNLTKQEDINRTYSYARLLMKEDYLINWNDSGYNIHKQILGLYPNCYTYINSKRLKVLESIPINNKYDEFLDFRYKDIILKSQSIINNNGLIIDIIENIGIIVQTKDVPLLITKVKLEGKKESSQNALIQQLTLTNSQNKLGE
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: GRPE_GEOSM
Sequence: MDKKKHDSHQHEKKADASQEKVEVAQPVSDADRIKELEEALAAKGLESAANWDKYLRERADLENYRKRVQKEKEEILKYGKEEIIVEILPALDNLERAIDHANEESAIVEGVRLTLSMLLSALKKFGVTPVDTPPGTPFNPEYHQAMGQVESADQEPNTVVAVFQKGYLLNERLLRPAMVTVAVKA
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEG6_MAIZE
Sequence: MVKNTDDVSVSTPAKEGIMQGNGAWCVVGFPPCKDNKCYCCIGGRTHARYSTMAECRHACF
What are the official names of this protein?
Protein MATERNALLY EXPRESSED GENE 6.
What is the protein family that this protein belongs to?
Belongs to the MEG family.
Protein: YBEY_MYCLB
Sequence: MSVEVSNESGFDVSEVELVSVARFVIIKMDVNPAAELSMVLLDTAAMADLHMRWMDLPGPTDVMSFPMDEFEPGGRPDAAEPGPSMLGDIVLCPEFAAQQAAAEGHSLGHELALLTIHGVLHLLGYDHGEPDEEKEMFALQGRLLEEWVAEQVRAYQHDRQNEKDCRLLYKSGYFGYL
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTLD_BACSU
Sequence: MIALHFGAGNIGRGFIGALLHHSGYDVVFADVNETMVSLLNEKKEYTVELAEEGRSSEIIGPVSAINSGSQTEELYRLMNEAALITTAVGPNVLKLIAPSIAEGLRRRNTANTLNIIACENMIGGSSFLKKEIYSHLTEAEQKSVSETVGFPNSAVDRIVPIQHHEDPLKVSVEPFFEWVIDESGFKGKTPVINGALFVDDLTPYIERKLFTVNTGHAVTAYVGYQRGLKTVKEAIDHPEIRRVVHSALLETGDYLVKSYGFKQTEHEQYIKKIIGRFENPFISDDVTRVARSPLRKLGENDRLVGPAKKIKEPNALAEGIAAALRFDFTGDPEAVELQALIEEKGYSGVLQEVCGIQSHEPLHAIILKKLNQ
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: LUKL2_STAAM
Sequence: MKNKKRVLIASSLSCAILLLSAATTQANSAHKDSQDQNKKEHVDKSQQKDKRNVTNKDKNSTVPDDIGKNGKITKRTETVYDEKTNILQNLQFDFIDDPTYDKNVLLVKKQGSIHSNLKFESHKEEKNSNWLKYPSEYHVDFQVKRNRKTEILDQLPKNKISTAKVDSTFSYSSGGKFDSTKGIGRTSSNSYSKTISYNQQNYDTIASGKNNNWHVHWSVIANDLKYGGEVKNRNDELLFYRNTRIATVENPELSFASKYRYPALVRSGFNPEFLTYLSNEKSNEKTQFEVTYTRNQDILKNRPGIHYAPSILEKNKDGQRLIVTYEVDWKNKTVKVVDKYSDDNKPYKEG
What are the official names of this protein?
Uncharacterized leukocidin-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the aerolysin family.
Protein: OXR2_MAGO7
Sequence: MKSFSLLASAGLATLASLPLTMAGVITPSYFDKHPLSRRQLSDAQVQRELGPQLSRGATIIGPGGPGWDDAIERFDNESRPTIRLVVVPAVESDIATVVKLANRFGIPFLVKNRGHALTNTIGRFRGIQIDMSRLTTITIQPGEPAESAWFQGGAWDKQAIEYLWDRGYVTVTGSCDCVGMMGPGLGGGHGRYQGLYGLISDNLINMNVVLADGSAVRVNATSNPDLWWGMQGAGHNLGIVTSFQSKIYPRKIDTWHYHSYTYTQDKLEAVFGALNTFHGNGDGSTPVLMGLNTGGFYIDPSVSQTEPVVSWVFGYAGPASEAEALLEPFSRLGPAAEQSGDVPYPGVATAMGTGQDQPLCQPGDAHVQVTSQFNVYNATAERALYQLFNRTIAAHPQLADSVAFHEGYSTAAVDRADPSASAVAFRDRKLLMFFDARLKPADAADPEVLGMAREFGRQVRRIWNEGAPDLKPATYVNYAAGDEPLESMYGYDAARLRRLRNIKRKYDPHGRFVYYNPIA
What is the function of this protein?
FAD-linked oxidoreductase; part of the gene cluster that mediates the biosynthesis of pyriculol and pyriculariol, two heptaketides that induce lesion formation upon application on rice leaves but are dispensable for pathogenicity (PubMed:27902426).  The highly reducing polyketide synthase synthesizes the heptaketide backbone of pyriculol and pyriculariol (PubMed:27902426).  Pyriculol and pyriculariol contain several hydroxyl moieties and double bonds, so it can be assumed that several reduction steps occur during biosynthesis.  These reactions could be executed by PKS19 itself or partly by the tailoring enzymes OXR1, OXR2, RED1, RED2 or RED3, identified within the cluster (Probable).  The FAD-linked oxidoreductase OXR1 is the only tailoring enzyme for which the function has been determined yet, and is involved in the oxidation of dihydropyriculol and dihydropyriculariol into pyriculol and pyriculariol, respectively (PubMed:27902426).
What are the official names of this protein?
FAD-linked oxidoreductase OXR2, Pyriculol/pyriculariol biosynthesis cluster protein OXR2.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
Protein: SOST_CHLAE
Sequence: MQLPLALCLVCLLVHAAFRVVEGQGWQAFKNDATEIIPELGEYPEPPPELENNKTMNRAENGGRPPHHPFETKDVSEYSCRELHFTRYVTDGPCRSAKPVTELVCSGQCGPARLLPNAIGRGKWWRPSGPDFRCIPDRYRAQRVQLLCPGGAAPRARKVRLVASCKCKRLTRFHNQSELKDFGPEAARPQKGRKPRPRARGAKANQAELENAY
What is the function of this protein?
Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.
What are the official names of this protein?
Sclerostin.
What is the protein family that this protein belongs to?
Belongs to the sclerostin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: G3P_GEOSE
Sequence: MAVKVGINGFGRIGRNVFRAALKNPDIEVVAVNDLTDANTLAHLLKYDSVHGRLDAEVSVNGNNLVVNGKEIIVKAERDPENLAWGEIGVDIVVESTGRFTKREDAAKHLEAGAKKVIISAPAKNEDITIVMGVNQDKYDPKAHHVISNASCTTNCLAPFAKVLHEQFGIVRGMMTTVHSYTNDQRILDLPHKDLRRARAAAESIIPTTTGAAKAVALVLPELKGKLNGMAMRVPTPNVSVVDLVAELEKEVTVEEVNAALKAAAEGELKGILAYSEEPLVSRDYNGSTVSSTIDALSTMVIDGKMVKVVSWYDNETGYSHRVVDLAAYIASKGL
What is the function of this protein?
Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD.  The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH.  The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, NAD-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTH_AROAE
Sequence: MSAAAPRLVVGLGNPGAEYTETRHNAGFRFCERLADKLGVRFSHESRFHGFVANARDAGVWLLMPQTYMNRSGQAVGALARFYRIAPAEILVVHDELDIPPGQLRLKFGGGLGGHNGLKDTSAHLATNDYWRLRIGIGHPGDRNEVVNYVLKPARREEQGQIDEALDRALAAWPMIARGEWNAATTRLNARPAALK
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YFFP_ECOLI
Sequence: MSLIRTETRDTKRAADPLHDLRSKPFSEWGEDEIRRFNLIDALLEFVYTDTSSPFGIGMTFDYTECWEIGVRDDCLVMTRVKPVHPEYAKHWNMKGVMNDKTRFHADKWVGYSKVLAWVSLSHKDTFTGAKRFQYFQTMYDMERQINANLPVGGLPNVDTERTGKLFQRDDFSEDSHANDPKLVGDDYVPQAPEQIN
What are the official names of this protein?
Uncharacterized protein YffP.
Protein: RL36_METNO
Sequence: MKIRNSLKSLRGRHRDNQIVRRKGRVYVINKTQKRYKARQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: YFEF9_CAEEL
Sequence: MLIQILFLIILTLNCSYSTSYSTSNGIRLMTFNIWNSGANVENGQQKIAKHILMVNPDVVALQEVYANVTRNLTLMLGHPWVAVERNHEYPDTAILTRHVLIPNTNLSTSGAVGVKIMLRTGFMIHFWSLHLDYTSYGPYAANNKLVDKLDQIMAGENVGRGPQIYEILNLPMMKKWMEKVEDVPIFIAGDFNGPSHLDWTEQTKKIHGDWVIRWPATKELEEREFSDTFREIYPNVVSDPGITWSTVNKFNPEWNYTIPEPQDRIDFLFYKGPVVPYQILTYSGCEKPQRIPFHSKNDYPSDHFAVFADYTFI
What are the official names of this protein?
Uncharacterized protein F14F9.5.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS4_FLAPJ
Sequence: MRIIPAIDIIDGKCVRLSKGDYNTKIIYNENPLEVAKKFEAHGVQYLHLVDLDGAKSSQIINYKILEKIASQTALKIDFGGGLKSDNDLRIAFESGANQITGGSIAVKNPEVFNEWIIKYGADKIILGADANNEKVAISGWLEESKEELIPFIQNYQNQGIEYVICTDIAKDGMLAGPSFNLYAKILSETKGIKLIASGGISTFDELPKLAQLGCEGTIIGKAIYENRITLKQLENFILNK
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2A_MYTCA
Sequence: MSGRGKGGKAKAKAKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYLAAVLEYLAAEVLELAGNAARDNKKSRIIPRHLQLAIRNDEELNKLLSGVTIAQGGVLPNIQAVLLPKKTQKAAK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: ACP_PHATC
Sequence: MKDNFTRLQSIVGKQLGIDPSKVKLESDFGRELGADSLDVVELVMAIEDEFEVNIEDQSASQIATVQDVLNYLERN
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CLC4M_HYLLA
Sequence: MSDSKEQRVQPLGLLEEDPTTSGIRLFPRDFQFQQTHGHKSSTGCLGHGPLVLQLLSFTLLAGVLVAILVQVYKVPSSLSQEQSEQDVIYQNLTQLKAAVGELSEKSKLQEIYQELIQLKAAVGELPEKSTLQEIYQELTRLKAAVGELPEKSRLQEIYQELTRLKAAVGELPEKSKQQEIYQELTRLKAAVGELPEKSKQQEIYQELTRLKAAVGELPEKSKQQEIYQELTRLKAAVGELPDQSKQQQIYQELTDLKTAFERLCCRCPKDWTFFQGNCYFISNSQRNWHDSVTACREVGAQLVVIKSAEEQNFLQLQSSRSNRFAWMGLSDLNQEGTWQWVDGSPLSSSFQRYWNSGEPNNSGDEDCAEFSGSGWNDNRCNVDNYWICKKPTACFRDE
What is the function of this protein?
Probable pathogen-recognition receptor involved in peripheral immune surveillance in liver.  May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments.  Probably recognizes in a calcium-dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens.  Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates (By similarity).
What are the official names of this protein?
C-type lectin domain family 4 member M, CD209 antigen-like protein 1.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: GRK_DROME
Sequence: MMQIPFTRIFKVIFVLSTIVAVTDCCSSRILLLREHTLKIVQHQHSHMHEHAHELQQQIQETAVELLNRLELQRKQLEASAQEEADQLHPDTDPNPDSGGQLPNADDSIAADPEQDGIILGSSTDTWLASESSTPITDSETVTTPETVTHTGEPPPDPSSSSTPDSTTPSPNDKETEIQMLPCSEAYNTSFCLNGGHCFQHPMVNNTVFHSCLCVNDYDGERCAYKSWNGDYIYSPPTAQRKVRMAHIVFSFPVLLMLSSLYVLFAAVFMLRNVPDYRRKQQQLHLHKQRFFVRC
What is the function of this protein?
Critical for defining the anterior-posterior and dorsal-ventral axes of the egg.  May signal directly to dorsal follicle cells through the receptor torpedo (top).  During oogenesis this signaling pathway instructs follicle cells to follow a dorsal pathway of development rather than the default ventral pathway.
What are the official names of this protein?
Protein gurken.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=Associates with the membranous cortex of yolk granules. Transiently inserted into the cell membrane, and then reinternalized during yolk uptake. cni is required for its transport to the oocyte cell membrane.
Protein: RK2_PELHO
Sequence: MAIHLYKTSTPSTRKRAVDSQGKSNPRNHLIYGQHRCGKGRNARGIITAGHRGGGHKRLYRQIDFRRNENNIYGRIVTIEYDPNRNAYICLIHYGDGEKRYILHPRGARIGDTIVSGTEVPIKMGNALPLTNIPLGTAIHNIEITLGKGGQLARAAGAVAKLISKEGKSAAVKLPSGEVRLISQNCSATVGQVGNVGVNRKSLGRAGSKRWLGKRPVVRGVAMNPVDHPHGGGEGKAPIGRKKPATPWGRPALGIRTRKRKKYNDNLILRRRSK
What are the official names of this protein?
50S ribosomal protein L2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MCBE_ECOLX
Sequence: MVTLKMAIIFLMEQIRTPFSLIWTIMSPTVLFFFLHFNEIELHYGDTAWLGKQISWFVGYISFSVVLFNYCLYLVGRRESGFIATFVHNMDGRLLFIRSQLIASLIMSILYVFFFILVVLTGFQASPDYQIVMIILKSIYINAFMMVSLTFMASFRVTFQTASTIYSVLITVCMVSGIVSLKYNEGIVYWINQVNPIAIYSTILQSDQELSLMTIFFYSIMLIISIISALTFKTEPVWSSQ
What is the function of this protein?
Together with two further proteins McbF and McbG this protein causes immunity to the peptide antibiotic microcin B17 (MccB17), which inhibits DNA replication in enterobacteriaceae.  Immunity is determined by two different mechanisms.  McbE is involved in the production of extracellular MccB17 and, in a complex with McbF it also serves as 'pump' for the export of active MccB17 from the cytoplasm to the periplasmic space.
What are the official names of this protein?
Protein McbE.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TUAG_BACSU
Sequence: MTNWKPLVSVITPSYNARDYIEDTVHSVLDQSHPHWEMIIVDDCSTDGTRDILQQYEKIDERIHVVYLEENSGAAVARNKALERAQGRYVAFLDSDDKWKKDKLEKQLEFMMERSCAFSFTGYSLMAQDGTPLDKFIHAPESLTYDDALKNTIIGCLTVMIDREQTGQIQMPNIRTRQDLATWLSLLKKGFTAYGMNECLAEYRLVNNSISSNKWKAAKKTWFVYREIERLHFMKATWCFVQYAKNAVKKRL
What are the official names of this protein?
Putative teichuronic acid biosynthesis glycosyltransferase TuaG.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
Protein: GLGA_ECOK1
Sequence: MQVLHVCSEMFPLLKTGGLADVIGALPAAQIADGVDARVLLPAFPDIRRGVTDAQVVSRRDTFAGHITLLFGHYNGVGIYLIDAPHLYDRPGSPYHDTNLFAYTDNVLRFALLGWVGAEMASGLDPFWRPDVVHAHDWHAGLAPAYLAARGRPAKSVFTVHNLAYQGMFYAHHMNDIQLPWSFFNIHGLEFNGQISFLKAGLYYADHITAVSPTYAREITEPQFAYGMEGLLQQRHREGRLSGVLNGVDEKIWSPETDLLLASRYTRDTLEDKAENKRQLQIAMGLKVDDKVPLFAVVSRLTSQKGLDLVLEALPGLLEQGGQLALLGAGDPVLQEGFLAAAAEYPGQVGVQIGYHEAFSHRIMGGADVILVPSRFEPCGLTQLYGLKYGTLPLVRRTGGLADTVSDCSLENLADGVASGFVFEDSNAWSLLRAIRRAFVLWSRPSLWRFVQRQAMAMDFSWQVAAKSYRELYYRLK
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: AMPA_PSEPK
Sequence: MELVVKSVAAASVKTATLVLPVGENRKLGTVAQAVDQACEGAISAVLKRGDLAGKPGQTLLLQNLSGLKAERVLLVGSGKEEALGDRAWRKLVASVAGVLKGLNGADAVLALDDIAVSNRDAHYGKYRLLAETLLDGEYVFDRFKSQKAEPRALKKVTLLADKAGQAEVERAVKHASAIASGMAFTRDLGNLPPNLCHPSYLAEQAKELGKAHKALKVEVLDEKKIKDLGMGAFYAVGQGSDQPPRLIVLNYQGGKKADKPFVLVGKGITFDTGGISLKPGAGMDEMKYDMCGAASVFGTLRAVLELQLPINLVCLLACAENMPSGGATRPGDIVTTMSGQTVEILNTDAEGRLVLCDTLTYAERFKPQAVIDIATLTGACIVALGSHTSGLMGNNDDLVGQLLDAGKRADDRAWQLPLFEEYQEQLDSPFADMGNIGGPKAGTITAGCFLSRFAKAYNWAHMDIAGTAWVSGGKDKGATGRPVPLLTQYLLDRAGA
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYK_CLOBH
Sequence: MSKEDNVMNSFEEQANELMKERFQKLKELQSNGKDPFDVYKVERTHTSKEVKENYEDLEGKTVTVAGRLMSKRVHGKAGFSDIHDRYGKIQLYIKINDVGEEKLKEYKTFDIGDIISVTGTVFKTKTGETSIHITDFQLVCKSLRPLPEKWHGLKDPDLRYRQRYVDLIINQDVRDTFMKRTAIIKTMREYLDNKGFLEVETPILSPIAGGAAAKPFITHHNALNIDMYLRIATELYLKRLIVGGFEKVYEIGRNFRNEGMDIRHNPEFTVIELYEAYADYNDMMEITENMIAYICEKVLGTTKVQYEGTEIDFTPPWRRLTMVDAVREYAGVDFNTIKDDIEARTIAKEKHIEFKKELKDCTKGDVLIGLFEEFCEDKLMQPTFICDYPVENSPLTKKKRGNEAFTERFEGFVFGREVCNAYSELNDSIVQKERFMQQLKERELGDDEAYMMDDDFITSLEVGMPPTGGLGIGIDRLIMFLTDTHSIRDVILFPTMKPQPNNQ
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.