PharMolix/UniProtQA huggingface dataset:
Protein: ECPC_ECO27
Sequence: MPLRRFSPGLKAQFAFGMVFLFVQPDASAADISAQQIGGVIIPQAFSQALQDGMSVPLYIHLAGSQGRQDDQRIGSAFIWLDDGQLRIRKIQLEESEDNASVSEQTRQQLMTLANAPFNEALTIPLTDNAQLDLSLRQLLLQLVVKREALGTVLRSRSEDIGQSSVNTLSSNLSYNFGVYNNQLRNGGSNTSSYLSLNNVTALREHHVVLDGSLYGIGSGQQDSELYKAMYERDFAGHRFAGGMLDTWNLQSLGPMTAISAGKIYGLSWGNQASSTIFDSSQSATPVIAFLPAAGEVHLTRDGRLLSVQNFTMGNHEVDTRGLPYGIYDVEVEVIVNGRVISKRTQRVNKLFSRGRGVGAPLAWQIWGGSFHMDRWSENGKKTRPAKESWLAGASTSGSLSTFSWAATGYGYDNQAVGETRLTLPLGVAINVNLQNMLASDSSWSNIASISATLPGGFSSLWVNQEKTRIGNQLRRSDADNRAIGGTLNLNSLWSKLGTFSISYNDDRRYNSHYYTADYYQSVYSGTFGSLGLRAGIQRYNNGDSSANTGKYIALDLSLPLGNWFSAGMTHQNGYTMANLSARKQFDEGTIRTVGANLSRAISGDTGDDKTLSGGAYAQFDARYASGTLNVNSAADGYINTNLTANGSVGWQGKNIAASGRTDGNAGVIFDTGLENDGQISAKINGRIFPLNGKRNYLPLSPYGRYEVELQNSKNSLDSYDIVSGRKSHLTLYPGNVAVIEPEVKQMVTVSGRIRAEDGTLLANARINNHIGRTRTDENGEFVMDVDKKYPTIDFRYSGNKTCEVALELNQARGAVWVGDVVCSGLSSWAAVTQTGEENES
What is the function of this protein?
Part of the ecpRABCDE operon, which encodes the E. coli common pilus (ECP).  ECP is found in both commensal and pathogenic strains and plays a dual role in early-stage biofilm development and host cell recognition (By similarity).
What are the official names of this protein?
Probable outer membrane usher protein EcpC.
What is the protein family that this protein belongs to?
Belongs to the EcpC/MatD family.
Protein: TUSD_ERWT9
Sequence: MRFCLMVTGPAYGSQHASSAWLFARELLAQGHSVESVFFYREGVLNASELTAPASDEVDMTRNWQQLHQQHGVALNVCVAAALRRGVSDKQEAANLGLAAANLAEGFQLTGLGALAEAALSCDRLVQF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.  Accepts sulfur from TusA and transfers it in turn to TusE.
What are the official names of this protein?
Sulfurtransferase TusD, tRNA 2-thiouridine synthesizing protein D.
What is the protein family that this protein belongs to?
Belongs to the DsrE/TusD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBS_HELAN
Sequence: MASISSSVATVSRTAPAQANMVAPFTGLKSNAAFPTTKKANDFSTLPSNGGRVQCMKVWPPLGLKKYETLSYLPPLTETQLAKEVDYLLRKKWVPCLEFELEHGFVYRENARSPGYYDGRYWTMWKLPMFGCTDSAQVMKELAECKKEYPQAWIRIIGFDNVRQVQCIMFIASRPDGY
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, chloroplastic, RuBisCO small subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CSK2A_THEPA
Sequence: MDQMDLVDTDKSRKYPAKDLKIILPKTYADVNSKKGPEYWDYENITLKWNVPDSYEIVRKIGRGKFSEVFEGINTVTKDKCVIKILKPVKKKKIKREIKILQNLRGGPNIIKLLDIVKDPQSRTPSLIFEHVNNTDFKTLYPTLSIQDIKYYIYQLLKAMNYCHSQGIMHRDIKPHNVMIDHEKKILRLIDWGLAEFYHPEQEYSVRVATRYYKGPELLVDMRYYDYSLDIWSIGCMLAGIIFKKEPFFYGHDNYDQLVKIAKVLGTEDLHRYFEKYGLKFAPAYQEILGNHSKKPWTKFVHHENQHLVSPEVMDLLDRMLVYDHTKRITPLEAMEHPFFNEIKNNSV
What is the function of this protein?
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates.  The alpha chain contains the catalytic site (By similarity).
What are the official names of this protein?
Casein kinase II subunit alpha, CK II.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KBAY_ECO27
Sequence: MSIISTKYLLQDAQANGYAVPAFNIHNAETIQAILEVCSEMRSPVILAGTPGTFKHIALEEIYALCSAYSMTYNMPLALHLDHHESRDDIRRKVHAGVRSAMIDGSHFPFAENVKLVKSVVDFCHSQDCSVEAELGRLGGVEDDMSVDAESAFLTDPQEAKRFVELTGVDSLAVAIGTAHGLYSKTPKIDFQRLAEIREVVDVPLVLHGASDVPDEFVRRTIELGVTKVNVATELKIAFAGAVKAWFAENPQGNDPRYYMRVGMDAMKEVVRNKINVCGSANRISA
What is the function of this protein?
Catalytic subunit of the tagatose-1,6-bisphosphate aldolase KbaYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6-bisphosphate (TBP).  Requires KbaZ subunit for full activity and stability.
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit KbaY, TBPA, TagBP aldolase, D-tagatose-bisphosphate aldolase class II, Ketose 1,6-bisphosphate aldolase class II, Tagatose-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class II fructose-bisphosphate aldolase family. TagBP aldolase KbaY subfamily.
Protein: PURA_CAMC1
Sequence: MRKADLVVGVQWGDEGKGKIVDMLGLNYDMICRSQGGHNAGHTIWVDGVRYALHLVPSGILHKNIINIIGNGVVVSPEVLITEMAQFDNLEGRLYISDKAHLNLSYHSQVDQAKERLKGEKAIGTTGKGIGPTYADKISRSGHRVGELLEPERLCDALMHDFETNKPVFDALGVKIPEENELLEELKRYKEVLAPFIANTTNLVWKALDEDKKVLLEGAQGTLLDIDHGTYPYVTSSNTISAGACTGLGLNPKEIGKVIGVIKAYTTRVGHGPFPTEDKGTNGDKMCEIGKEFGTTTGRRRRCGWFDAVSVKYASRLDGVDTYALMKLDVLDGFEVVKICKAYQYNGETIDYVPTDLENATPIYEELAGWDSVKGISRYEDLPANARAYIERIEELTGVKVGYISTSPERSDTIIR
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECF_THEFY
Sequence: MHVSHLQLADYRSYEAAYLELEPGVSTFIGPNGQGKTNLVEAIGYVATHSSHRVAHDAPLVRRGAQRAVIRAAVVRHGQTALIELEINPGRANRARLNRSPNTRMRDVLGILHTVLFAPEDLALVKGDPGERRRFLDELLTARAPRYAGVRSDYERVLKQRNALLKSAAAQNLHHRGGRDLPTLDVWDEHLAQIGAELLAARLALVAELQPLAAKAYGELTATQDPISLRYRCSATDEELDTTNRPQLVEILRAALLRARPDELRRGVSLVGPHRDDLQLWLNDLPAKGYASQGESWSYALALRLAGFELLRADGDDPVLLLDDVFAELDAERRRRLASYVRTAEQVLVTAAVPDDVPQELSGARFRVTGGSVERER
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBB_OENBI
Sequence: MGLPWYRVHTVVLNDPGRLLAVHIMHTALVAGWAGSMALYELAVFDPSDPVLDPMWRQGMFVIPFMTRLGITNSWGGWSITGGTVTNPGIWSYEGVAGSHILFSGLCFLAAIWHWVYWDLAIFSDERTGKPSLDLPKIFGIHLFLSGLACFGFGAFHVTGLYGPGIWVSDPYGLTGEVQPVNPAWGVEGFDPFVPGGIASHHIAAGTLGILAGLFHLSVRPPQRLYKGLRMGNIETVLSSSIAAVFFAAFVVAGTMWYGSATTPIELFGPTRYQWDQGYFQQEIYRRVGAGLAKNQSLSEAWSKIPEKLAFYDYIGNNPAKGGLFRAGSMDSGDGIAVGWLGHPIFRDKEGRELFVRRMPTFFETFPVVLVDGDGIVRADVPFRRAESKYSVEQVGVTIEFYGGELNGVSYSDPATVKKYARRAQLGEIFELDRATLKSDGVFRSSPRGWFTFGHASFALLFFFGHIWHGARTLFRDVFAGIDPDLDTQVEFGAFQKLGDPTTRRQAV
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP47 reaction center protein, PSII 47 kDa protein, Protein CP-47.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: DNAA_STAAR
Sequence: MSEKEIWEKVLEIAQEKLSAVSYSTFLKDTELYTIKDGEAIVLSSIPFNANWLNQQYAEIIQAILFDVVGYEVKPHFITTEELANYSNNETATPKEATKPSTETTEDNHVLGREQFNAHNTFDTFVIGPGNRFPHAASLAVAEAPAKAYNPLFIYGGVGLGKTHLMHAIGHHVLDNNPDAKVIYTSSEKFTNEFIKSIRDNEGEAFRERYRNIDVLLIDDIQFIQNKVQTQEEFFYTFNELHQNNKQIVISSDRPPKEIAQLEDRLRSRFEWGLIVDITPPDYETRMAILQKKIEEEKLDIPPEALNYIANQIQSNIRELEGALTRLLAYSQLLGKPITTELTAEALKDIIQAPKSKKITIQDIQKIVGQYYNVRIEDFSAKKRTKSIAYPRQIAMYLSRELTDFSLPKIGEEFGGRDHTTVIHAHEKISKDLKEDPIFKQEVENLEKEIRNV
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPA_NATPD
Sequence: MSSRRRKPEWLRTRPPSGRRFTEIKETLRDRDLNTVCEEANCPNLGDCWSGRDGPGTATFMLLGDRCSRGCNFCDVATGGMDPLDPDEPANVAEAVAEIGLDYVVLTSVDRDDLDDGGAGHFAETIREIKRRDTSVLVEALIPDFQGDTDAVDRIIDADPDVVAHNVETVERLQWPVRDRRAGYEQSLDVLRQIAAADGCYAKTSLMLGVGEYAHEVYRTLGDLSEVGVDIVTFGQYLQPSRSHLEVFEYVTPDTFDVWKRVAETEFGFLYCASGPMVRSSFKAGELFVEALERDGLDIEAARAAAERQ
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y523_METJA
Sequence: MGEMENIIYSIYHPTILVGFAIGILSLLAIGFQKNDLHALILTDVVECAMLIIIAGVGTDLAEALILPGLVVSLAELLAVSEVLITRKYLKSKRPKPKSYKLFEEFKLPLYTGELKYDIHMEILKTSPKFLAIILIVYGAILSGFTGGAVIATGLLFYALSQRVIGVEISEELKTMWEGISGLSGIAWALWIFGFIGFFVFPDKWLLCLLMAGLGLVIKVGSKLGLIGYIGEVR
What are the official names of this protein?
Uncharacterized protein MJ0523.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: COF_SHIF8
Sequence: MARLVAFDMDGTLLMPDHHLGEKTLSTLARLRERDITLTFATGRHALEMQHILGALSLDAYLITGNGTRVHSLEGELLHRDDLPADVAELVLYQQWDTRASMHIFNDDGWFTGKESPALLQVFVYSGFRYQIIDVKKMPLGSVTKICFCGDHDDLTRLQIQLYEALGERAHLCFSATDCLEVLPVGCNKGAALTVRTQHLGLSLRDCMAFGDAMNDREMLGSVGSGFIMGNAMPQLRAELPHLPVIGHCRNQAVSHYLTHWLDYPHLPYSPE
What is the function of this protein?
Catalyzes the hydrolysis of 4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5-hydroxymethylpyrimidine phosphate (HMP-P).
What are the official names of this protein?
HMP-PP phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. Cof family.
Protein: SLEB_BACSU
Sequence: MKSKGSIMACLILFSFTITTFINTETISAFSNQVIQRGATGDDVVELQARLQYNGYYNGKIDGVYGWGTYWAVRNFQDQFGLKEVDGLVGAKTKQTLICKSKYYREYVMEQLNKGNTFTHYGKIPLKYQTKPSKAATQKARQQAEARQKQPAEKTTQKPKANANKQQNNTPAKARKQDAVAANMPGGFSNNDIRLLAQAVYGEARGEPYEGQVAIAAVILNRLNSPLFPNSVAGVIFEPLAFTAVADGQIYMQPNETAREAVLDAINGWDPSEEALYYFNPDTATSPWIWGRPQIKRIGKHIFCE
What is the function of this protein?
Could be a lytic transglycosylase.  Required for spore cortex hydrolysis during germination.  Interacts strongly but noncovalently with spore components.
What are the official names of this protein?
Spore cortex-lytic enzyme, SCLE.
What is the protein family that this protein belongs to?
Belongs to the SleB family.
What are the subcellular locations of this protein?
Forespore. Note=Expressed in the forespore and then transported across the inner forespore membrane and deposited on the outside of the cortex.
Protein: CU187_LOCMI
Sequence: GYLSLPADTPEVAAAKVAHFAAYNAAAARSAGVVAVAPSYGYAAYGPANIVIGADGVPLDTPEVAARKAADAVAHARAAAGLPAVGPVPAAVVPAVVGSVPADTPEVAAAKVAHAAAHVEANVRNAAEAVGIHGLYGVVPSVYSYGVVPGAYSVHYDGTLLTPDGVPLDTPAVAAGKVANAVAHIKAKSGLIV
What is the function of this protein?
Component of the cuticle of migratory locust which contains more than 100 different structural proteins.
What are the official names of this protein?
Cuticle protein 18.7, LmNCP18.7.
Protein: PSD2_CLOAB
Sequence: MSITIFNRDLKEIYYEKQYKNGQLKFLYNTILGRMLLKLFISTRLFSKINAIFNNNKGSIKKIEPFINEYKIDMSEYEKKEYTSFDDFFTRKILEGKRSFSKEKSHLISPADSKLMVYEIDDDLKMNIKNSIYTVGELLNDEKLSREYKNGTCLIFRLTVDDYHRYCFIDDGSLKYRKVINGRLHTVGPISSKRYKVYSENNREYSVLKTRNFGKVIQIEVGALLVGKIKNHSIKVFKKGDEKGYFCFGGSTIVLLFKEKVIKMDEDILEYSKAGIETKIKMGEKIGETND
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme 2.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type II sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: DMR14_CRYX8
Sequence: MEEAETNTQVDSVPSNSVRSGAELSSKSKLRDSCHACARSKVRCPKQKPSCSRCEARGTTCQYFFSRRPGRRRETSKSPNPEKQIAIGSSHANNRNSPSFSSTRSTLPSPIASDSNSNFTQPQNSSITTVHNGPENSIESPCWEDFSCEFSDTDFVMPTIDTPFDLSPAYSGSVVQEMNDTAPFPLSSSRISMGTTPSGKSSISSYSQILPSITPTTTPVAHISSCRCLATALDLLKTLSLAGLADADSLVSAPIILAENKQSIESVNNLMACPLCSGDSFPLTIFSMIALKILERYAVAARTQHQGTRPQEAEGTVEIKLADIVISNNEDQTRLPSHSNIVCCDDKTQARAAAQLVLGELHHMQRLVNQLSSMIKRSAERDGRKLEILNGYNDSIDSGNSMLASFSASTLELVESDVRKSLRSLSTDIIKELRQH
What is the function of this protein?
Transcriptional regulator; part of the gene cluster that mediates the biosynthesis of the dimeric xanthones cryptosporioptides.
What are the official names of this protein?
Transcriptional regulator dmxR14, Dimeric xanthone biosynthesis cluster protein R14.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y916_DESAP
Sequence: MTMTSEEVITLIDEEGVEHDFTVLDILEVDGTEYAILIPVDDEEQEDEVVIFKFTEDDEGNEILVEIEDDEWEKVADAWQEKVGREH
What are the official names of this protein?
UPF0473 protein Daud_0916.
What is the protein family that this protein belongs to?
Belongs to the UPF0473 family.
Protein: IL2RB_HUMAN
Sequence: MAAPALSWRLPLLILLLPLATSWASAAVNGTSQFTCFYNSRANISCVWSQDGALQDTSCQVHAWPDRRRWNQTCELLPVSQASWACNLILGAPDSQKLTTVDIVTLRVLCREGVRWRVMAIQDFKPFENLRLMAPISLQVVHVETHRCNISWEISQASHYFERHLEFEARTLSPGHTWEEAPLLTLKQKQEWICLETLTPDTQYEFQVRVKPLQGEFTTWSPWSQPLAFRTKPAALGKDTIPWLGHLLVGLSGAFGFIILVYLLINCRNTGPWLKKVLKCNTPDPSKFFSQLSSEHGGDVQKWLSSPFPSSSFSPGGLAPEISPLEVLERDKVTQLLLQQDKVPEPASLSSNHSLTSCFTNQGYFFFHLPDALEIEACQVYFTYDPYSEEDPDEGVAGAPTGSSPQPLQPLSGEDDAYCTFPSRDDLLLFSPSLLGGPSPPSTAPGGSGAGEERMPPSLQERVPRDWDPQPLGPPTPGVPDLVDFQPPPELVLREAGEEVPDAGPREGVSFPWSRPPGQGEFRALNARLPLNTDAYLSLQELQGQDPTHLV
What is the function of this protein?
Receptor for interleukin-2.  This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.  Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15 (PubMed:15123770, PubMed:31040185).
What are the official names of this protein?
Interleukin-2 receptor subunit beta, IL-2 receptor subunit beta, IL-2R subunit beta, IL-2RB, High affinity IL-2 receptor subunit beta, Interleukin-15 receptor subunit beta, p70-75, p75.
What is the protein family that this protein belongs to?
Belongs to the type I cytokine receptor family. Type 4 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: OXDA_TRIVR
Sequence: MAKIVVIGAGVAGLTTALQLLRKGHEVTIVSEFTPGDLSIGYTSPWAGANWLTFYDGGKLADYDAVSYPILRELARSSPEAGIRLISQRSHVLKRDLPKLEVAMSAICQRNPWFKNTVDSFEIIEDRSRIVHDDVAYLVEFRSVCIHTGVYLNWLMSQCLSLGATVVKRRVNHIKDANLLHSSGSRPDVIVNCSGLFARFLGGVEDKKMYPIRGQVVLVRNSLPFMASFSSTPEKENEDEALYIMTRFDGTSIIGGCFQPNNWSSEPDPSLTHRILSRALDRFPELTKDGPLDIVRECVGHRPGREGGPRVELEKIPGVGFVVHNYGAAGAGYQSSYGMADEAVSYVERALTRPNL
What are the official names of this protein?
D-amino-acid oxidase, DAAO, DAMOX, DAO.
What is the protein family that this protein belongs to?
Belongs to the DAMOX/DASOX family.
Protein: HDFR_YERPA
Sequence: MDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLENQLGANLFTRHRNNIRLTPAGERLVPYAEMLLNTWRLAKKEVIHSLQHTELSIGATASLWEAYLTPWLQQLYEQQEELRLEARIALRNSLVKQLHERQLDLLITTEPPKMDELACLLLGHFSLRLYSSFSLDLPKEDDTPNEHKNASEVPYIKLEWGADFHQQENRLLDSEQAPILTTTSAHLTRQLLETTGGCAFLPEHWQKEYPQLVIHPDIPPIVRPLYAVWLQNSDQQALIRQLLKTPMNNATQSVTRE
What is the function of this protein?
Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.
What are the official names of this protein?
HTH-type transcriptional regulator HdfR, H-NS-dependent flhDC regulator.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: RL13_SHIBS
Sequence: MKTFTAKPETVKRDWYVVDATGKTLGRLATELARRLRGKHKAEYTPHVDTGDYIIVLNADKVAVTGNKCTDKVYYHHTGHIGGIKQATFEEMIARRPERVIEIAVKGMLPKGPLGRAMFRKLKVYAGNEHNHAAQQPQVLDI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RBFA_BUCAP
Sequence: MDKLFNRSFRIAQELQKNIAFIIQHSLKDPRIKTIITVSEVRLSKDLSYAQVFVSFLETNSNLTVKKVLILLNRASGYIRKLLCKKMNLRIIPIIVFFHDDSFFKGNKISKLLNILTEKNNITL
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_WOLWR
Sequence: MECNLVNLSNDNVGTAQLNPLIFSAKQKLSILHDIVRWQLAKRRAGTHKTKGISDVSGTTAKPYGQKRTGRARQGSLRSPQFRGGGIIFGPVVRSHTYSLNKKVRKFGLKIALSLKYLNNQVIILDNLNIDVKKTSEMCKCIKNFKFSSFLIVGDYGDDLLRAAKNLHYVDLIKPIGLNVFDILNHECVMLTKDTLKHLEGRLL
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: END4_MESHJ
Sequence: MIKIGSHVRFRKPDYLFGAIQESLENKANTAMIFLGPPQSTFRVKPENYKLQDYQKHFFKQIPPEDIIVHAPYIINPASPIKAQFSNDFLVKEIEKINYIGAKFLVLHPGFFTSFTKEVAKKQLISSLKSILEKTKNVILLLETMSGKGSEMCANFEEIVEIVEAVESPRIGICLDTCHVWDAGYDLKNFPEFCKEIRRTRLINYLKVIHLNDSLSPLGSKKDRHANIGKGFIGLESLRKIIFDPLFANIPKILETPYVDNKPIYDQEIALLLKKV
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: RECF_LIMRD
Sequence: MILTELHLHHFRNYQDLTVHFNPGVNVLIGHNAQGKTNMLEAIYVLSLTKSHRTSNDHELINWQEKSALISGTVEKSIGKIPLELQFSSKGKKAKVNHLEQARLSQYVGQLNAILFAPEDLSLVKGSPALRRHFMDREFSQMSSKYLYNAGQYRTLLRQKNKYLKQLKYRQQTDRVLLGVLSDQLAAFGAEVIIARQHFLKHLEGWAADLHQEISLNKESLRLEYVNQLKVSDDTTVEEAYQALFKLYQDNEQREIEQGTTIYGPHRDDIRFLVNDKNVQAFGSQGQQRTTALSVKLAEIDLMKEQTGEYPLLLLDDVLSELDTIRQTHLLTAIQNKVQTFLTTTSLSDVARQLINEPTIFEIEHGTLNKEEVK
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRAF6_HUMAN
Sequence: MSLLNCENSCGSSQSESDCCVAMASSCSAVTKDDSVGGTASTGNLSSSFMEEIQGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQLFPDNFAKREILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALMDCPQCQRPFQKFHINIHILKDCPRRQVSCDNCAASMAFEDKEIHDQNCPLANVICEYCNTILIREQMPNHYDLDCPTAPIPCTFSTFGCHEKMQRNHLARHLQENTQSHMRMLAQAVHSLSVIPDSGYISEVRNFQETIHQLEGRLVRQDHQIRELTAKMETQSMYVSELKRTIRTLEDKVAEIEAQQCNGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHLEALRQRTFIKDDTLLVRCEVSTRFDMGSLRREGFQPRSTDAGV
What is the function of this protein?
E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2 (PubMed:11057907, PubMed:18347055, PubMed:19713527, PubMed:19465916).  Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation (PubMed:19675569).  Leads to the activation of NF-kappa-B and JUN (PubMed:16378096, PubMed:17135271, PubMed:17703191).  Seems to also play a role in dendritic cells (DCs) maturation and/or activation (By similarity).  Represses c-Myb-mediated transactivation, in B-lymphocytes (PubMed:18093978, PubMed:18758450).  Adapter protein that seems to play a role in signal transduction initiated via TNF receptor, IL-1 receptor and IL-17 receptor (PubMed:8837778, PubMed:19825828, PubMed:12140561).  Regulates osteoclast differentiation by mediating the activation of adapter protein complex 1 (AP-1) and NF-kappa-B, in response to RANK-L stimulation (By similarity).  Together with MAP3K8, mediates CD40 signals that activate ERK in B-cells and macrophages, and thus may play a role in the regulation of immunoglobulin production (By similarity).  Participates also in the TCR signaling by ubiquitinating LAT (PubMed:25907557, PubMed:23514740).
What are the official names of this protein?
TNF receptor-associated factor 6, E3 ubiquitin-protein ligase TRAF6, Interleukin-1 signal transducer, RING finger protein 85, RING-type E3 ubiquitin transferase TRAF6.
What is the protein family that this protein belongs to?
Belongs to the TNF receptor-associated factor family. A subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cell cortex. Nucleus. Lipid droplet. Note=Found in the nuclei of some aggressive B-cell lymphoma cell lines as well as in the nuclei of both resting and activated T- and B-lymphocytes. Found in punctate nuclear body protein complexes. Ubiquitination may occur in the cytoplasm and sumoylation in the nucleus. RSAD2/viperin recruits it to the lipid droplet (By similarity).
Protein: CK096_MOUSE
Sequence: MAFAVIRACSRVGRGGLYKRLGGPPRGTRRQRQRPRQGRQGASRSIAEQRSAAPRPPTGPPARYPSPAASARASEARRHPAADLDPPPGEPQAVASRGTPEPRPPPESPGAPPPPGSAPADGAMAAAKPGELMGICSSYQAVMPHFVCLTDEFPQPVRPAKLPKGKGRLRRPRQSRFKTQPVTFDEIQEVEEEGVSPMEEEKAKKSFLQSLECLRRSTQSLSLQREPLGQLQTEEQPGLQRLRLGPVRR
What are the official names of this protein?
Uncharacterized protein C11orf96 homolog, Protein Ag2 homolog.
Protein: RECR_CALS4
Sequence: MSYYSTSVAKLIEELSKLPGIGPKTAQRLAFFIINMPLDEVRSLSQAIIEAKEKLRYCKICFNITDKEVCDICSDENRDHSTICVVSHPMDVVAMEKVKEYKGVYHVLHGVISPIEGVGPEDIRIKELLERVRDGSVKEVILATNPDIEGEATAMYIAKLLKPFGVKVTRIAHGIPVGGDLEYTDVVTLSKALEGRREV
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: YHCO_ECO57
Sequence: MNIYTFDFDEIESQEDFYRDFSQTFGLAKDKVRDLDSLWDVLMNDVLPLPLEIEFVHLGEKTRRRFGALILLFDEAEEELEGHLRFNVRH
What are the official names of this protein?
Uncharacterized protein YhcO.
What is the protein family that this protein belongs to?
Belongs to the barstar family.