PharMolix/UniProtQA huggingface dataset:
Protein: RL6_PARPJ
Sequence: MSRVGKSPVALQGAEVALSDDRITVKGPLGTITQAANRLVKVVNDNGTLNFEPVDESREANAMSGTMRALVANMVNGVTKGFERKLTLVGVGYRAQAQGDKLNLSLGFSHPVVHQMPEGVKAETPTQTEIVIKGINKQQVGQVAAEVRGYRPPEPYKGKGVRYANEVVILKETKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RL15_NOSP7
Sequence: MRLHDVKPQKGSKKRKKRVARGISAGQGASAGLGMRGQKSRSGSGTRPGFEGGQQPLYRRLPKLKGFPIVNQKIYTTINVEKLASLPANTEVTLASLKAAGILTAVKGPLKILGNGELSTPLKVQAAAFTGTARSKIEAAGGSCEVL
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: H4_DIAPU
Sequence: MTGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFWQNVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H4.
What is the protein family that this protein belongs to?
Belongs to the histone H4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: ENGB_LIMF3
Sequence: MQVHDVELTISAVEENQYPATALPELALVGRSNVGKSSLTNVLINRKNYAHTSGQPGKTQTLNFYEVEHKLYFVDVPGYGYAKVSKKQREKFGKMIENYLTTREQLRGVVQLVDGRHAPTEDDRMMFQWLAYYHIPTLVVATKVDKVKPNAHNRIVKVVKEGLGAAKDQDLILFSATTKKGAESVWQWIEERTGVSD
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: CCS1_PAUCH
Sequence: MKHVLKWISDLRVAIFLLLIIALSSSLGTALPQKESAESYYEAYNSSPWLKVFSGESIIQLQLDHVYSSDWFLSLLLWLGIALVFCSWRRQLPALQFTLRWIDYCNPRQLSKLALAETIISTDASASIKRLEQLLKNQGWQVQAKSGRLAARRGIAGRVGPLMVHTGLVILMLGAVWGVLGGHRLERFLAPGREMELLNSHGKSQLNIALESFQIERDPVGRPEQYRSQLRLRELGNSRENNSGSIDKSLNREISVNHPLRYGGMTVYQADWALAAITVQLGRSPLLQLPLEQFPQLGEQVWGVVLPTQQDGSNPVLLALSSEKGPIEVFASDGSLITTLRPGGVAATINDVKVRVESILPASGLLLKRDPGVPLVYIGFAVALMGGGLSLISTRQIWAIAELEQQRFHVGGLCNREFTNFAQELPQFISEIQQI
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsB.
What is the protein family that this protein belongs to?
Belongs to the Ccs1/CcsB family.
What are the subcellular locations of this protein?
Plastid, organellar chromatophore thylakoid membrane; Multi-pass membrane protein.
Protein: FADI_ECO45
Sequence: MGQVLPLVTRQGDRIAIVSGLRTPFARQATAFHGIPAVDLGKMVVGELLARTEIPAEVIEQLVFGQVVQMPEAPNIAREIVLGTGMNVHTDAYSVSRACATSFQAVANVAESLMAGTIRAGIAGGADSSSVLPIGVSKKLARVLVDVNKARTMSQRLKLFSRLRLRDLMPVPPAVAEYSTGLRMGDTAEQMAKTYGITREQQDALAHRSHQRAAQAWSEGKLKEEVMTAFIPPYKQPLVEDNNIRGNSSLADYAKLRPAFDRKHGTVTAANSTPLTDGAAAVILMTESRAKELGLVPLGYLRSYAFTAIDVWQDMLLGPAWSTPLALERAGLTMGDLTLIDMHEAFAAQTLANIQLLGSERFARDVLGRAHATGEVDESKFNVLGGSIAYGHPFAATGARMITQTLHELRRRGGGFGLVTACAAGGLGAAMVLEAE
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, ACSs, Acetyl-CoA acyltransferase, Acyl-CoA ligase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_BURCM
Sequence: MSNSRQHQGHFARKRFGQNFLVDHGVIDSIVTTIGPARGQRMVEIGPGLGALTEPLIARLATPESPLHAVELDRDLIGRLQQRFGPLLELHAGDALAFDFRSLAAPGDKPSLRIVGNLPYNISSPLLFHLMTFADAVIDQHFMLQNEVVERMVAEPGTKAFSRLSVMLQYRYVMEKMLDVPPESFQPPPKVDSAIVRMIPYEPHELPDVDPVLLGELVTAAFSQRRKMLRNTLGDYRETIDFDGLGFDLARRAEDVSVAEYVGVAQALAARRKAAE
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COMT1_SACOF
Sequence: MGSTAEDVAAVADEEACMYAMQLASASILPMTLKNALELGLLEVLQAEAPAGKALAPEEVVARLPVAPTNPDAADMVDRMLRLLASYDVVKCQMEDKDGKYERRYSAAPVGKWLTPNEDGVSMAALTLMNQDKVLMESWYYLKDAVLDGGIPFNKAYGMTAFEYHGTDPRFNRVFNEGMKNHSVIITKKLLEFYTGFEGVSTLVDVGGGIGATLHAITSHHPQIKGINFDLPHVISEAPPFPGVQHVGGDMFKSVPAGDAILMKWILHDWSDAHCATLLKNCYDALPENGKVIIVECVLPVNTEAVPKAQGVFHVDMIMLAHNPGGRERYEREFHDLAKGAGFSGFKATYIYANAWAIEFIK
What is the function of this protein?
Catalyzes the conversion of caffeic acid to ferulic acid and of 5-hydroxyferulic acid to sinapic acid.  The resulting products may subsequently be converted to the corresponding alcohols that are incorporated into lignins.
What are the official names of this protein?
Caffeic acid 3-O-methyltransferase, CAOMT, COMT, S-adenosysl-L-methionine:caffeic acid 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. COMT subfamily.
Protein: DAPD_PSEA7
Sequence: MSQSLFSLAFGVGTQNRQDAWLEVFYALPLLNPSAEIVAAVAPILGYSSGNQALAFTSQQAYQLADALKGIDAAQSALLSRLAESQKPLVATLLAEDAAPSSTPEAYLKLHLLSHRLVKPHGVNLSGIFPLLPNVAWTNIGAVDLAELAELQLEARLKGKLLEVFSVDKFPKMTDYVVPAGVRIADTARVRLGAYIGEGTTVMHEGFVNFNAGTEGPGMIEGRVSAGVFVGKGSDLGGGCSTMGTLSGGGNIVISVGEGCLIGANAGIGIPLGDRNIVEAGLYITAGTKVALLDEQNTLVKVVKARDLAGQPDLLFRRNSQNGAVECKTNKTAIELNEALHAHN
What is the function of this protein?
Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EST3_PONAB
Sequence: MRLHRLRARLNAVAFGLLLLLVHGQGPEIVQPEVDTTLGRVRGRQVGVKGTDRLVNVFLGIPFAQPPLGPDRFSAPHPAQPWEGVRDASAAPPMCLQDVESMNNSRFVLNGKQQIFSVSEDCLVLNIYSPAEATAGAGRPVMVWVHGGALITGAATSYDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVVAALRWVQGNITPFGGDLNCVTVFGGSAGGSIVSGLVLSPMAAGLFHRAITQSGVITTPGIIESHPWPLAQKITNTLACSSSSPAEMVQCLRQKEGEELVLSKKLKSTIYPLTVDGTVFPKSPKELLKEKPFHSVPFLMGVNNHEFSWLIPRGWGLLDTMEQMSREDMLAISTPVLTSLDVPPEMMPTVIDEYLGSNSDAQAKCLAFQEFMGDVFINVPTVSFSRYLRDSGSPVFFYEFQHRPSSFAKIKPAWVKADHAAEGAFVFGGPFLMDESSRLAFPEATEEEKQLSLTMMAQWTHFARTGDPNSKGLPPWPRFNQAEQYLEINPVPRAGQKFRETRMQFWSETLPSKIQQWHQKQKNRKAQEDL
What is the function of this protein?
Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs.
What are the official names of this protein?
Carboxylesterase 3, Liver carboxylesterase 31 homolog.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: FABH_PROM5
Sequence: MEVINSNQIGVSFKGSGSYVPHQILTNHEISKKVDTSDEWIKSRTGISQRRISGLSENVSEMGYKAGLAAIEMAKWDIETIDLIILATSTPHDLFGSAPEIQSKLGANNAVAFDLTAACSGFLFAVITATQFLKAGSYRRAIVIGSDQLSSYVDWNDRRSCILFGDGAGALAIEATNEFDNLIGFSMRTDGQRGSFLNLPSQKNNDQIIDNINFSSGGFSTIAMNGQEVYKFAVREVPLIIDNLFKKTNFNSEKINWLLLHQANQRILDSVGDRLNISSEKILSNLSNYGNTSAATIPLMLDEAIRNKKIKENDIIATSGFGAGLSWGAALIRWG
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_XANAC
Sequence: MATTLNPSEISDLIKTRIEAVKLSAESRNEGSVTSVSDGIVRIFGLADVMQGEMIELPNNTFALALNLERDSVGAVVLGDYESLREGDVAKTTGRILEVPVGPELLGRVVNALGEPIDGKGPLGATQTAPVERVAPGVIWRKSVDQPVQTGYKSVDAMIPIGRGQRELVIGDRQTGKTALAIDAVINQKGTGIKCVYVAIGQKASTVANIVRKLEENGALAHTVVVAATASESAAMQYISPYAGCTMGEYFMDRGEDALIVYDDLSKQAVAYRQISLLLKRPPGREAYPGDVFYLHSRLLERAARVSEEYVEKFTNGAVTGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLFNAGIRPAVNAGISVSRVGGAAQTKIIKKLSGGIRISLAQYRELAAFAQFASDLDEATRKQLERGQRVTELMKQKQYAPMSIANQALSIYAVNEGYLDDVPVNKLLAFEEGLHAHFANTQGELVSKINSTGGWDNDIEASFKKGIEEFKTTGSW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RADA_BACSU
Sequence: MAKTKSKFICQSCGYESPKWMGKCPGCGAWNTMVEEMIKKAPANRRAAFSHSVQTVQKPSPITSIETSEEPRVKTQLGEFNRVLGGGVVKGSLVLIGGDPGIGKSTLLLQVSAQLSGSSNSVLYISGEESVKQTKLRADRLGINNPSLHVLSETDMEYISSAIQEMNPSFVVVDSIQTVYQSDITSAPGSVSQVRECTAELMKIAKTKGIPIFIVGHVTKEGSIAGPRLLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEMGIFEMREEGLTEVLNPSEIFLEERSAGSAGSSITASMEGTRPILVEIQALISPTSFGNPRRMATGIDHNRVSLLMAVLEKRVGLLLQNQDAYLKVAGGVKLDEPAIDLAIVISIASSFRDTPPNPADCFIGEVGLTGEVRRVSRIEQRVKEAAKLGFKRMIIPAANLDGWTKPKGIEVIGVANVAEALRTSLGG
What is the function of this protein?
Plays a role in DNA repair (PubMed:9141693, PubMed:11810266).  Might stabilize or process Holliday junction intermediates (PubMed:15317759).  May work with DisA following methyl methanesulfonate (MMS) but not H(2)O(2) damage; DisA is a DNA integrity scanning protein with c-di-AMP synthase activity.
What are the official names of this protein?
DNA repair protein RadA, Branch migration protein RadA, DNA repair protein Sms.
What is the protein family that this protein belongs to?
Belongs to the RecA family. RadA subfamily.
Protein: BGAL1_THESP
Sequence: MLGVCYYPEHWPKARWKEDARRMREAGLSYVRVGEFAWALLEPEPGRLEWGWLDEALATLAAEGLKVVLGTPTATPPKWLVDRYPEVLPVDREGRRRRFGGRRHYCFSSPAYREEARRIVTLLAERYGGLEAVAGFQTDNEYGCHGTVRCYCPRCQEAFRGWLKARYGTIEALNEAWGTAFWSQRYRNFTEVELPHLTVAEPNPSHLLDYYRFASDQVRAFNRLQVEILRAHAPGKFITHNFMGFFTDLDAFALAQDLDFASWDSYPLGFTDLMPLPPEEKLRYARTGHPDVAAFHHDLYRGVGRGRFWVMEQQPGPVNWAPHNPSPTPGMVRLWTWEALAHGAEVVSYFRWRQAPFAQEQMHAGLHRPDSAPDQGFFEAKQVAEELAALALPPVAQAPVALVFDYEAAWVYEVQPQGAEWSYLGLIYLFYSALRRLGLDVDVVPPGASLRGYALTVVPSLPIVRGEALKAFQEAEGIVLFGPRSGSKTETFQIPRELPPGPLQALLPLKVVRVESLPPGLLEVAEGPMGRFSLGLWREWVESPLRPWLAFADGGGALYREGRYLYLAAWPSPELLGVLLAGLAQEAGLRPVFLPEGLRLRRRGPWVFAFNYGPEAVEAPAPEGARFLLGGKRVGPYDLAVWEEA
What is the function of this protein?
Hydrolyzes chromogen 5-bromo-4-chloro-3-indolyl-beta-D-galactopyranoside (X-Gal) and p-nitrophenyl-beta-D-galactoside (pNPGal).
What are the official names of this protein?
Beta-galactosidase BgaA, Beta-gal.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 42 family.
Protein: CODY_OCEIH
Sequence: MDLLSRARKINAMLQTATGKSVNFNEMSASLRDVIRGNVYIVSRRGKLLGFAVNQEIENERMKSMLEERQFPEEYTRGLHDIRETTPNLDIESTHTVFPVENKELFKDGLTTIVPIIGGGERLGTLILGRVNESFSDDDLLLGEYGATVVGMEILHEKTEEIEMEARSKAVVQMAISSLSYSELEAIDHIFEELNGKEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGTYIKVLNDKFLVELEKLRSR
What is the function of this protein?
DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability.  During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.
What are the official names of this protein?
Global transcriptional regulator CodY.
What is the protein family that this protein belongs to?
Belongs to the CodY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPR31_HUMAN
Sequence: MPFPNCSAPSTVVATAVGVLLGLECGLGLLGNAVALWTFLFRVRVWKPYAVYLLNLALADLLLAACLPFLAAFYLSLQAWHLGRVGCWALHFLLDLSRSVGMAFLAAVALDRYLRVVHPRLKVNLLSPQAALGVSGLVWLLMVALTCPGLLISEAAQNSTRCHSFYSRADGSFSIIWQEALSCLQFVLPFGLIVFCNAGIIRALQKRLREPEKQPKLQRAQALVTLVVVLFALCFLPCFLARVLMHIFQNLGSCRALCAVAHTSDVTGSLTYLHSVLNPVVYCFSSPTFRSSYRRVFHTLRGKGQAAEPPDFNPRDSYS
What is the function of this protein?
Proton-sensing G protein-coupled receptor.
What are the official names of this protein?
12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor, 12-(S)-HETE receptor, 12-HETER, G-protein coupled receptor 31, GPR31/12-HETER.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RRF_ECO8A
Sequence: MISDIRKDAEVRMDKCVEAFKTQISKIRTGRASPSLLDGIVVEYYGTPTPLRQLASVTVEDSRTLKINVFDRSMSPAVEKAIMASDLGLNPNSAGSDIRVPLPPLTEERRKDLTKIVRGEAEQARVAVRNVRRDANDKVKALLKDKEISEDDDRRSQDDVQKLTDAAIKKIEAALADKEAELMQF
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
Protein: USF2_RAT
Sequence: MDMLDPGLDPASSATAAAAASHDKGPEAEEGVELQEGGDGPGAEEQTAVAIASVQQAAFGDHNIQYQFRTESNGGQVTYRVVQVTDGQLDGQGDAAGAVSVVSTAAFAGGQQAVTQVGVDGAAQRPGPAAASVPTGPAAPFPLAVIQNPFSNGGSPAAEAVSGEARFAYFPASSVGDTTAVSVQTTDQSLQAGGQFYVMMTPQDVLQTGTQRTIAPRTHPYSPKIDGTRTPRDERRRAQHNEVERRRRDKINNWIVQLSKIIPDCHADNSKTGASKGGILSKACDYIRELRQTNQRMQETFKEAERLQMDNELLRQQIEELKNENALLRAQLQQHNLEMVGESTRQ
What is the function of this protein?
Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters.
What are the official names of this protein?
Upstream stimulatory factor 2, Major late transcription factor 2, Upstream transcription factor 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: YQY2_CAEEL
Sequence: MSEVSYDILENPEPNSHLWKQWKNLVDTEGWTSDDNSVTALTPSMPSTRSVWAVSKTAENDFVGCVIWNEYNKICFLGFFLLAPEYRGKGVGSVIWDIAMSRMPADHTLGLRGVPSMVDKYRKKATPFVGATLENYKMKVAEYHASMEKMTGDNFKLVSHLTPVEFDQLVRYDSDVNGRNRREFLELYYKLDCVLGVVLFDQHHKIIAHISAVRTSHKEDNVFKIAPLYADSPSIAMSALRVFSGVMFELHPEADVLFHLLDVGSGAFLQSFFQSLEIIPAVSGVTLFSNEWPNKGDLSKVFIAHNNSCHFDY
What is the function of this protein?
To the C-terminal of C. elegans F21C10. 9.
What are the official names of this protein?
Uncharacterized protein F36G3.2.
Protein: CBID_PSESM
Sequence: MREETAEQPAPLRSGLTTGSCATATSLAAARLLLSGQISDAVEIVLPKGKQVQMRLEFCRRVDNFAEAGTLKDAGDDPDVTHGALVFARVRQEAAPGVRFVAGAGVGSVTRPGLVLAVGEPAINPVPRRMMTEHLLRLAEELGYSGGFEVTIGVEGGEALALKTMNPRLGILGGLSILGTSGIVRPFSCAAYIASIHQGIDVATTNGYRHIAACTGNASEDTMRRVYNIPDIALIEMGDFVGAVLKHLRKVPVDKLSLCGGFGKISKLAAGHMDLHSRHSSIDLPQLALWAAQVGADAALQQQILHANTSQQALAMCAAAGVPLGDEVCRHALAFARSVVPATVEVEVFAIDRQGGVVGQAGVALSKEHT
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: MED24_XENLA
Sequence: MKLVNLKQAILQAWKERWSDYQWAINMKKFFPKGVTWDILNLAEALLDQAMIGPAPNPLILSYLKYAINSQMVSYSTVLTAISKFDDFSRDLCIQSLLEIMDMFCDNLSCHGKAEECIGLCRALMSALNWLLRCATFYTDKLKDVLDPVAGENHLSMCLQRLKSILGSTKNRALIHIAKLEEPTSWTSVEQSQLRLSESISLLPSVQLRNQAEECVSLIRSIPSMLSVHSDQLQTNGFPTVHAVVMLEGTMNLTGDAQPLVEQMNTVKRMQRIPLHLFLLEVWKACIVGLIESPEGTEELKWTAFTFLKIPQALAKLKKLSSMEQDFNEDMKCAFEYLLKLTPLLDKADQRCNCDCVSLLLQECNKLGLLSEQNMENLMAKRTADREQAPRLKSSENSTIQPNPGLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFIQLNEFTRHIGVESSKAANVRALLFDISFLMLCHVAQTYGSEMILSEGCPGGEMPFFESWMQTCMPGEGRVLNPDHPCFRHPDIAKVEALVALLNTSTEMKLAQTKWHEVCLSIPAAILEIHNAWENGVLSSEAIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDERDKSLQMIRQLGSPMFGDNTLQFYSERVIIMSSILDNMCSEVLQQTTTQIKFSAAGSEPMPYIHRLPPKTPIKEVLRGAFSSTLEKGWVDSRTLHNFDTLLHMGGVYWFCNNLVKELLRETRLEFALRAVELLYAIFCLDMQQLTLTLLGHVLPSLLTDSAKWHMLMDPPGRALAKLSVWCAMTSYSTQNKGQPSPRQRKRHREDIEDYSSLFPLDDTQQSKLMRLLSSNEEEHNVQANPVDRPMNSSLSASQIHNISSKEPLNRVLANLFLLISSVLGAKTAGAQTQFVQWFMEECVESLELGGKGCILQFMPFSMVSELVKVSTLSSPKIVLAITDLTLPLGRRVAAKALTAL
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 24, Mediator complex subunit 24.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 24 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CAPC_BACSU
Sequence: MFGSDLYIALILGVLLSLIFAEKTGIVPAGLVVPGYLGLVFNQPVFILLVLLVSLLTYVIVKYGLSKFMILYGRRKFAAMLITGIVLKIAFDFLYPIVPFEIAEFRGIGIIVPGLIANTIQKQGLTITFGSTLLLSGATFAIMFVYYLI
What is the function of this protein?
Required for PGA (gamma-polyglutamic acid) biosynthesis.
What are the official names of this protein?
PGA biosynthesis protein CapC.
Protein: SCRL1_ORYSJ
Sequence: MIRYQIRNEYGLSDPELYAPGEKDDPEALLEGVAMAGLVGVLRQLGDLAEFAAEIFHDLHEDVMATASRGHGLMLRLRQLEAEFPAVEKAIISQSDHSNYPHDDGVEWHTNLQIDQNMITQGDMPRFILDSYEECRGPPRLFTLDKFDVAGAGASLKRYSDPSFFKTEHSSDMIETDAVIEKKPRKIKKKALRWRKGETLESLLIANSESHTTSKDRSSRKVPPRTTKLKYRYPRESDHKNISRICREHLQEIISSQQKIFSNYSSRYYHPKFRLTESSETASSFGEIDNFSARAQSSAKLELTKVVPINEFDTKGIAPTHINGSDCLEALEADDRQLQATQHEPDKVEDVCKRSLVEQNAMLSNSDRMQSVQEENLLSAMVPADQNDDRCRPDDTGSDQENFVDALNNMESEGEAHAEMKIKKDPGAKMELDELNFHRDEGENERHTEFSELGHVIDSSPWLNDSYNGGEPNHAISSNTNFSGVDCTNDEEPSNDVDLMEMDVSSSSSVFSDDNDVFRTNGNMNGFQQYQEASLSNDHHAVIAHSSDKQSSQKSSGLDGSSIESNDFIEKPFHSLEDDKNFAPDGTSVILGRPNDVSQCEEEIEVGNADDSLLQPTISNQEVHRSNNQLEGVAMHASISSGKVASFPDMDPGMCTKDLELDNVLVPKETVANTPPTGLGTDHIHEHVDELDSGVAPINSSIQSDSTYESDDDDMAEDLNSLPEDDLYKHDVEDLYKHVLEDDGIIALGKGPCSTRANMHQEDPMEVSDVRGDFSNGQELPVLTETASPQGELVGGGELPLLTETASPQGGEEDLADEVVVISSRDLNDEKKPSLAEVPLACGDASLLDSSASCLEHDESTETGEIAKSDEVLVNVEVAEESITGRFTDDMTPFQEDLPDGAKYSEDAEFLANPRVDNSRHDVQLQSSSPCREELETVKAPCENLCALDESREHIFEKSVLQINNLPQHIETKNTGEACSDIDDIQHLSALHCPKNPVCQEELPDETNLSADVQYHCDVEKGGAVILNSKMVEEQPENIDLVREPRAQDSFGTNPFMDPGYKANHALADPCPSYQPCFSEEEQDFISELLIPHGNMGIEDLNPVPVADSLWEPATPPDEVPLPSEVMTEEDFRSFCHEYHEMDLTATPESIDDKPASDSNVVSSSLVTSESEFLYCVSAVRTGVDQEESRDAPDDTLMHFSAKADPDDKAANSDLKSDEPFIDEKIHELGVPSVPMELEVEQHALHEVDSHGDSQLLDNDMIDETCSSPSGNSIAVKDKQETCANLVSRAFINERTDELEVPVSNSVLLEPSEEVHDSDEYNYQDVPWSSTDEGRDEVDAHPLSKRIQTQGSEALVLGELDSRAVPSCSVNEMADHVDAPPLSTVLEAEQEPEDCISGEHNSQVTKSSLVDEKIGELDDASPLSNTLLAEMEREVCVPGKSASQIASCSPTPSNEKIDELNAPPLSSSGLIELESEDSVSGDLDSQIIPCSSPNDKTNEPDGATSTHVLPVELEQEVCSFPELDSLVAPCSLNDDKVCELDEPPCKQLESENGSYCLPQVDCQIEPCYSESVVLSEASTMSSANAMPSTEETYRLSSPVPPPNEPFSNVSYEDPQKPPPLPPLLWRLGKPRLGIASTKGHMLEPERGKGPVLHTSDAGMDNMPGCLSGMTESIEPVSSQEIKERHLDPILDNNERGVEFRRLATPPTANDVAVTEHVQLFSDACENIKHQERVSSSETEAEEHQNGTGITDVMDSHPPKPLFLVPSISQQGLQGSVFPSDTSDNGEHSSYTSRAVSEDEKTVDDHNAACAMDLHITSSSASSHVSENGCNQQSHGESLPVTSVDKVHTSDASCEDNKLKNHFITSEVCSDATNLSASGLLTEEENIHNVEDQYEGPLPSEESSGCLDYPHDDHNSEKEDIHQPDGYAASPGNNNHFDSSHEGGYLHAEQPPVMGWTVRPQMLHPNYGISMEENQFEPKVEDHLLIKKPVSIRNIPRNPLVDAVAAHDRSTMRKVSELVAPTDKSKPNERNLLLEQIRNKTFNLKPVSSAKQPTIRTPPRASTRNLKVAAIIEKANAIRQAVGSDDEDGDNWSESSDT
What is the function of this protein?
Involved in regulation of actin and microtubule organization.  Part of a WAVE complex that activates the Arp2/3 complex (By similarity).
What are the official names of this protein?
SCAR-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the SCAR/WAVE family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RS4_ECO57
Sequence: MARYLGPKLKLSRREGTDLFLKSGVRAIDTKCKIEQAPGQHGARKPRLSDYGVQLREKQKVRRIYGVLERQFRNYYKEAARLKGNTGENLLALLEGRLDNVVYRMGFGATRAEARQLVSHKAIMVNGRVVNIASYQVSPNDVVSIREKAKKQSRVKAALELAEQREKPTWLEVDAGKMEGTFKRKPERSDLSADINEHLIVELYSK
What is the function of this protein?
Also functions as a rho-dependent antiterminator of rRNA transcription, increasing the synthesis of rRNA under conditions of excess protein, allowing a more rapid return to homeostasis.  Binds directly to RNA polymerase (By similarity).
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: CYTC_MOUSE
Sequence: MASPLRSLLFLLAVLAVAWAATPKQGPRMLGAPEEADANEEGVRRALDFAVSEYNKGSNDAYHSRAIQVVRARKQLVAGVNYFLDVEMGRTTCTKSQTNLTDCPFHDQPHLMRKALCSFQIYSVPWKGTHSLTKFSCKNA
What is the function of this protein?
As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity.
What are the official names of this protein?
Cystatin-C, Cystatin-3.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL14_LISMH
Sequence: MIQQESRMKVADNSGAREVLTIKVLGGSGRKTANIGDVVVCTVKQATPGGVVKKGEVVKAVIVRTKSGARRQDGSYIKFDENACVIIRDDKSPRGTRIFGPVARELRENNFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.