PharMolix/UniProtQA huggingface dataset:
Protein: SSRP_SODGM
Sequence: MTKKKEHKPGSATIAQNKRARHEYFIEQEFEAGLSLQGWEVKSLRAGKANIGDSYVLLKDGEAYLFGATFQPLTVASSHVVCDPMRTRKLLLNKRELDSLFGRVNREGYTVVALSLYWKNAWVKVKIGVAKGKKEYDKRTDIKEREWQLDKSRIMKHASR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: LIPA_CHLPD
Sequence: MSNVLARKPDWLKLRLSAHGEFAATRQLLEQRNLNTVCRSAMCPNLQECWSRGTATFLLLGNICTRTCRFCAVGTASIPPMPDSLEPENIAEAVEIMNLNHVVLTSVNRDDLADGGARHWQKTMQAVRQRNPKVTLECLIPDFQAQTEALDIVLAEAPEVLNHNIETVPSIYHIVRPEANYSSSLNIIRRAKEHFNLTTKSGLMVGMGETFDEVVQSLHDLVQHGCDMVTIGQYLQPSASHIPVNRYVTPEEFDRYKTVAESLGLRNVRSGPFVRSSYLAETLSPDH
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_MAGMM
Sequence: MSSIVEIHGREVIDSRGNPTVEVDVYTEDGGFGRAAVPSGASTGSREAVELRDGDKSRFLGKGVRKAVDAVNTVLAEVVLGMEVADQKGIDAAMIALDGTHNKSRLGANAILGISMAVAKAAADECDLPLYRYLGGTNTSLLPVPMMNIINGGAHADNNVDIQEFMIMPVAATSCTEAIRMGAEVFHSLKKVLKSKGLNTAVGDEGGFAPNLGSNEEALKVIVEAIEAAGYKPGEDIKLALDCASSEFYNKETGNYDLTGEGRVLTKQELVAFYEDLVAKYPIISIEDGFDESDWDGWKLMTEALGNKIQLVGDDLFVTNSKILAEGISKGIANSILVKVNQIGTLTETFEAVEMAQRAGYTAVISHRSGETEDATIADIAVALNAGQIKTGSMSRSDRIAKYNQLIRIEEELGGMARFEGMKVFYNLR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: TYSY_WIGBR
Sequence: MKEYLDLLNLILKNGYPKIDRTKTGTLSMFGYQIRINLNEGFPLLTTKYCHFKSIVYELLWFLRGDTNISFLKKNNISIWNKWADKNGNLGPIYGKQWRAWEDKKNNTIDQIEIALNKLKKEPSSRRILVSSWNVGELDLMSIPPCHVLFQLYVINNKLSCQVYQRSCDIFLGLPFNIGSYALLTHIFANQCDLLVEDLIWTGGDIHLYKNHLNQAKLQLTRSPLPLPKIFIKKKPKNLFNYAFNDFLLIDYNHHPKIKAPISI
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NHAB_YERPP
Sequence: MDITNRQAVLKNFLGNSPDWYKLAIMGFLIINPLVFFFVSPFVAGWMLVIEFIFTLAMALKCYPLQPGGLLAIQAVAIGMTSPHQVAEEIANNLEVLLLLVFMVAGIYFMKQLLLFVFTKLLLNIRSKTILSLAFCLASAFLSAFLDALTVIAVVISVSVGFYTIYHNVTSNHSDKDITDDSGIDNQDSHETLEQFRAFLRSLMMHAGVGTALGGVMTMVGEPQNLIIAKSAGWNFADFFIRMLPVTLPVFIFGLLVCLLVEKFKLFGYGAQLPERVRQVLTEYDQQANAKRTKQEKMKLIVQAIIGVWLVLALALHLAEVGLVGLSVIILATSFCGITNEHSLGKAFQEALPFTALLTVFFAVVAVIIEQSLFTPIIQFVLQASPSAQLSLFYLFNGLLSSVSDNVFVGTVYINEARSAFEHGIVSLQQFELLAVAINTGTNLPSVATPNGQAAFLFLLTSALAPLIRLSYGRMVYMALPYTLVMTIVGLLGVEFLLVPMTEWLTQAGWISLPHITNGVAIPH
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaB, Sodium/proton antiporter NhaB.
What is the protein family that this protein belongs to?
Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS28B_SCHPO
Sequence: MDSSKVPVKLAKVIKVLGRTGSRGGVTQVRVEFMDDTSRSIIRNVKGPVREDDILVLLESEREARRLR
What are the official names of this protein?
40S ribosomal protein S28-B, S33.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS28 family.
Protein: 4HYPE_CERS4
Sequence: MRVQDVYNVIYTHTEGEPLCIIYSGVPYPAGSTILEKRAFLEENYDWLRKALMREPRGHADMFGVFLTPPSSRDYDAGLIYIDGKEYSHMCGHGTIAVAMAMVANGLVARDPSGLTRIRFETTAGLVVAEVAHEGDRVLWTRFENVPAYVAAQDIAFELPGYGPLKADLVWGGNYFGIIDLRGTSLRIAPENGSELSRMGLIAREEIRKKVKVQHPTEAHINNLNFVTFWHEPTIEGCLYKNVHVFSAGQLDRSPGGTGTSAMMAYFEARGVIGLNQPITSEGLLGSGTFEGCLIGETTLGTVRAVRPTVKGTAGMLGTASWTINREDPVDAGFLVL
What is the function of this protein?
Catalyzes the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp).  Is involved in a degradation pathway that converts t4LHyp to alpha-ketoglutarate, which allows R. sphaeroides to grow on t4LHyp as a sole carbon source.  Displays no proline racemase activity.
What are the official names of this protein?
4-hydroxyproline 2-epimerase, 4Hyp 2-epimerase, 4HypE.
What is the protein family that this protein belongs to?
Belongs to the proline racemase family.
Protein: AROE_PYRNV
Sequence: MYFAVIGTHVRGKSASPAMHNASFKALGVNAVYIAVDVPREELPCFLKLARLNLRGFNVTIPHKEEVVKHLDGVAADARAIGAVNTVLVERNLLVGYNTDASAVYQLAGSHMRGADVLIVGAGGAARAALFAAIKAEARAVYIANRTYERAEALAREFAEKFKREVKAVRSPVKADVVVNATPVYDAMVADLSGASLYVDFAYIPTPRTKMVEEAQRLGIKVVDGVDLLVEQGAQAEKIWLGVEPDRTVMKRAVLEFLGI
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: ASSY_ECOLI
Sequence: MTTILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEEDYDAIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNTTPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDTDFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEYLNSSVKIVNPIMGVKFWDESVKIPAEEVTVRFEQGHPVALNGKTFSDDVEMMLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHAHGRQLGRLLYQGRWFDSQALMLRDSLQRWVASQITGEVTLELRRGNDYSILNTVSENLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFGYAKTGLLSSSAASGVPQVENLENKGQ
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_BORDL
Sequence: MKIAILLSGGVDSSVALYTMIQKGYKNIKCYYLKIWLEDELSYIGECPWKEDITYVDSVCKKFNVPYEIINLQEEYYNRVVTYAIEELKMGNTPSPDIFCNQRIKFGAFFEKINEKYDLIVTGHYAKIENKNNSYTLKQAKDKIKDQSYFLSHLSKKQISKLHFPLGDLLKSEIRQIAHEIDLPNKNRKDSQGICFLGKIKYNEFIKYHLGELKGNIIEQETGKILGTHNGYWFFTIGQRKGIKLSHGPWFVTEKDIQNNIIYISNSTNYLKQGKEQFLVHKTNWINKPLKNDNLSAKIRHGEKKIKCKIETLKDEIIRVNLEEKDYGISPGQFCIFYKEDECLGGAKILKTLI
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HYPA_SYNAS
Sequence: MHELSLVSSILDIIEDYAAQDGFRRVNNLRLSCGRLSGVDLQCLRFAFEVLSRETRSEGATLEIDFLPIVISCLNCGEDTEVEYVEASCPECGSENVLLAGGTEELRLLELDVD
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: ASP39_ARATH
Sequence: MELRRKLCIVVAVFVIVIEFASANFVFKAQHKFAGKKKNLEHFKSHDTRRHSRMLASIDLPLGGDSRVDSVGLYFTKIKLGSPPKEYHVQVDTGSDILWINCKPCPKCPTKTNLNFRLSLFDMNASSTSKKVGCDDDFCSFISQSDSCQPALGCSYHIVYADESTSDGKFIRDMLTLEQVTGDLKTGPLGQEVVFGCGSDQSGQLGNGDSAVDGVMGFGQSNTSVLSQLAATGDAKRVFSHCLDNVKGGGIFAVGVVDSPKVKTTPMVPNQMHYNVMLMGMDVDGTSLDLPRSIVRNGGTIVDSGTTLAYFPKVLYDSLIETILARQPVKLHIVEETFQCFSFSTNVDEAFPPVSFEFEDSVKLTVYPHDYLFTLEEELYCFGWQAGGLTTDERSEVILLGDLVLSNKLVVYDLDNEVIGWADHNCSSSIKIKDGSGGVYSVGADNLSSAPRLLMITKLLTILSPLIVMAFTSLA
What is the function of this protein?
Displays aspartic proteolytic activity (PubMed:27872247).  Together with A36, contributes to pollen and ovule development, including the apical cell wall constitution of the growing pollen tubes (PubMed:27872247).
What are the official names of this protein?
Aspartic proteinase 39.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Cytoplasm, cytosol. Note=Displays punctate cytosolic localization and colocalizes with the GPI-anchored protein COBL10 at the plasma membrane and in the cytosol (PubMed:27872247). In pollen grains, mainly present at the plasma membrane and in reticular structures in the cytosol (PubMed:27872247). In pollen tubes, exhibits a punctate localization in the cytosol and occurs weakly at the plasma membrane (PubMed:27872247).
Protein: ULAE_SHIB3
Sequence: MLSKQIPLGIYEKALPAGECWLERLRLAKTLGFDFVEMSVDETDERLSRLDWSREQRLALVNAIVETGVRVPSMCLSAHRRFPLGSEDDAVRAQGLEIMRKAIQFAQDVGIRVIQLAGYDVYYQEANNETRRHFRDGLKESVEMASRAQVTLAMEIMDYPLMNSISKALGYAHYLNNPWFQLYPDIGNLSAWDNDVQMELQAGIGHIVAVHVKDTKPGVFKNVPFGEGVVDFERCFETLKQSGYCGPYLIEMWSETAEDPAAEVVKARDWVKARMAKAGMVEAA
What is the function of this protein?
Catalyzes the isomerization of L-xylulose-5-phosphate to L-ribulose-5-phosphate.  Is involved in the anaerobic L-ascorbate utilization.
What are the official names of this protein?
L-ribulose-5-phosphate 3-epimerase UlaE, L-ascorbate utilization protein E, L-xylulose-5-phosphate 3-epimerase.
What is the protein family that this protein belongs to?
Belongs to the L-ribulose-5-phosphate 3-epimerase family.
Protein: SSRP_RHILW
Sequence: MAPKGSQRVVNKVVAENRKARFNYEIIDTYEAGLVLMGTEVKSLREGKANIAESYASDEGGEIWLINSYLPEYLQANRFNHEPRRRRKLLLSGREIHRLRSAVNREGMTLIPLKIYFNDRGRAKMELALAKGKKLHDKRESEKERDWNRQKSRLLKDNG
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: P19_TBSVB
Sequence: MERAIQGNDAREQAYGERWNGGSGSSTSPFKLPDESPSWTEWRLHNDETISNQDNPLGFKESWGFGKVVFKRYLRYERTETSLHRVLGSWTGDSVNYAASRFLGFDQIGCTYSIRFRGVSVTISGGSRTLQHLSEMAIRSKQELLQLTPVEVESDVSRGCPEGIETFKEESE
What is the function of this protein?
Viral suppressor of RNA silencing which binds specifically to silencing RNAs (siRNAs).  Acts as a molecular caliper to specifically select siRNAs based on the length of the duplex region of the RNA (By similarity).
What are the official names of this protein?
RNA silencing suppressor p19, 19 kDa symptom severity modulator.
What is the protein family that this protein belongs to?
Belongs to the tombusvirus protein p19 family.
Protein: RECR_STRP2
Sequence: MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFAKNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHGLYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLLKPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: LEUC_ALISL
Sequence: MSNAKTLYEKVYDAHVAVAAKGETPILYIDRHLVHEVTSPQAFDGLREKGRNVRQVGKTFATMDHNVSTQTKDINASGEMARIQMETLSKNCEEFGVTLYDLNHKYQGIVHVMGPELGITLPGMTIVCGDSHTATHGAFGSLAFGIGTSEVEHVLATQTLKQARAKTMKIEVKGKVTEGITAKDIVLAIIGKTTAAGGTGYVVEFCGEAITDLTMEGRMTVCNMAIELGAKAGLIAPDATTFDYITGRKFSPQGEDLTAAIEYWSSLKTDDDAKFDAVVSLDASEIKPQVTWGTNPGQVIAIDQPIPAPESFSDPVEKVSAEKALAYMGLEAGKSLTDYNVDKVFVGSCTNSRIEDIRAAAAVAKGNKVAAHVQALIVPGSEQVKAQAEKEGLDIIFKEAGFEWRLPGCSMCLAMNNDRLGPQERCASTSNRNFEGRQGRDGRTHLVSPAMAAAAAIAGHFVDIRTITEKA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: TATB_AZOSB
Sequence: MFDFGFSELVVIGVVMLIVVGPERLPKVARTAGHLLGRLQRYVSDVKSDIQREMQLEELKKLQQQVQQQAQALESSVRTEVAQVESSVDQVVAAIKADAAPPDNTTSAESQAAADPAAVDSSQQLELRLDTTPKQVVGSDKA
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: CDYL2_HUMAN
Sequence: MASGDLYEVERIVDKRKNKKGKWEYLIRWKGYGSTEDTWEPEHHLLHCEEFIDEFNGLHMSKDKRIKSGKQSSTSKLLRDSRGPSVEKLSHRPSDPGKSKGTSHKRKRINPPLAKPKKGYSGKPSSGGDRATKTVSYRTTPSGLQIMPLKKSQNGMENGDAGSEKDERHFGNGSHQPGLDLNDHVGEQDMGECDVNHATLAENGLGSALTNGGLNLHSPVKRKLEAEKDYVFDKRLRYSVRQNESNCRFRDIVVRKEEGFTHILLSSQTSDNNALTPEIMKEVRRALCNAATDDSKLLLLSAVGSVFCSGLDYSYLIGRLSSDRRKESTRIAEAIRDFVKAFIQFKKPIVVAINGPALGLGASILPLCDIVWASEKAWFQTPYATIRLTPAGCSSYTFPQILGVALANEMLFCGRKLTAQEACSRGLVSQVFWPTTFSQEVMLRVKEMASCSAVVLEESKCLVRSFLKSVLEDVNEKECLMLKQLWSSSKGLDSLFSYLQDKIYEV
What are the official names of this protein?
Chromodomain Y-like protein 2, CDY-like 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: THIM_LACCB
Sequence: MSKVITDVFYTAFKTALPLTSSPLVQCITNEITVESMANALLYIDAKPVMADDQREFPEFFAQSDALLLNLGHISEVRQQNLLAAGKFAQATNQPTVIDLVGVSATQLRYDLGHQLLANHPNVVKGNISEMRRFADLKSTGRGVDGSQLDQSATALGELAASLQQLTQAFPTTTFLATGKIDLVVSAKGTWYLKNGVPQLDRFTGTGDIVGALIAALLGTGLDNDAAVVVAVSYFNCCGEVAAAQNRTGGLAAFREGTLNQLSLLAATADWLQMVKGEAL
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: ACT_OXYRB
Sequence: KIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEG
What is the function of this protein?
Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth.
What are the official names of this protein?
Actin.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: MDTK_SALTI
Sequence: MQKYTSEARQLLALAIPVILAQVAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLVMIVLWNAGYIIRSMHNIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFLGLLVNIPVNYIFIYGHFGMPELGGIGCGVATAAVYWVMFIAMLSYIKHARSMRDIRNEKGFGKPDSVVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLGVGICMAVVTAIFTVTLRKHIALLYNDNPEVVALAAQLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFFITFTAYWVLGLPSGYILALTDLVVDRMGPAGFWMGFIIGLTSAAVLMMLRMRYLQRQPSAIILQRAAR
What is the function of this protein?
Multidrug efflux pump that functions probably as a Na(+)/drug antiporter.
What are the official names of this protein?
Multidrug resistance protein MdtK, Multidrug-efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYB_ABRAN
Sequence: MTIMRKTHPLLKIINHSFIDLPAPSNISSWWNFGSLLGICLMIQILTGLFLAMHYTSDTATAFSSVTHICRDVNYGWLIRYLHANGASMFFICMFIHVGRGIYYGSYMLSETWNIGIILLLTTMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTSLVEWIWGGFSVDKATLTRFFAFHFILPFIITAFVLVHLLFLHETGSNNPSGLNSNSDKIPFHPYYTIKDLLGVIFLLMVLMILVLFFPDVLGDPDNYTPANPLNTPAHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILATFPLLKSSKQHGLMYRPITQTLYWVFISNLLILTWIGGQPVEYPFTTIGQIASISYFTIIVILMPIANMIENNILKLYY
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PUR5_ACET2
Sequence: MTTYKDAGVDVEAGYEAVRLMRNDVKRTFRPEVLTDIGGFGGLFGLNKDKYSEPVLVSGTDGVGTKLKIAFLLDKHDTVGIDCVAMCVNDIVCSGAEPLFFLDYIALGKNRPEKVAQIVKGIADGCVEAGCALIGGETAEMPGFYPEDEYDLAGFAVGIVEKSKIIDGSKIKAGDKLIGLASSGIHSNGYSLVRKILAPTAKKLAEEIKMLGTTLGEELIKPTRLYVKTILDLKEKFEIKGIAHITGGGFIENIPRMLPQGLGVKVVRGSWPVLPIFTLLKDLGNLDEMDMYNTFNMGIGMTIAVDAEIANSVVEYLNKDKEQAYIIGEVVSDKEGLEIC
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_PRIM3
Sequence: MNKKTLKDIDVKGKRVFCRVDFNVPMKDGKVTDETRIRAAIPTIQYLVEQGAKVILASHLGRPKGEVVEELRLNAVAERLQALLGKDVAKADEAFGEEVKKTIDGMSEGDVLVLENVRFYPGEEKNDPELAKAFAELADVYVNDAFGAAHRAHASTEGIAQHIPAVAGFLMEKELDVLSKALSNPERPFTAIVGGAKVKDKIGVIDHLLDKVDNLIIGGGLSYTFIKALGHEVGKSLLEEDKIELAKSFMEKAKKNGVNFYMPVDVVVADDFSNDANIQVVSIEDIPSDWEGLDAGPKTREIYADVIKNSKLVIWNGPMGVFELDAFANGTKAVAEALAEATDTYSVIGGGDSAAAVEKFNLADKMSHISTGGGASLEFMEGKELPGVVALNDK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSGA_CLOBB
Sequence: MKGKIIKGIAGFYYVKVEENLIECKARGKFRHKDVKPMVGDNVVIQVENGKGVIESIEKRSSELLRPAVANISLAFVVFAIKSPDINFDLLNKFLVLCEYNHIEAIVCLNKVDLVSEEERENVKKRINDIGYEVLYINAKEGLGTDILKEKINGNITVLCGPSGAGKSTLINKLTNKEHMLTGIVSEKIGRGKHTTRHSELIEVSNGYIVDTPGFSTLEIKELMNKEDLKYCFPEFEEHNESCKYRGCLHNKEPKCTVKQAVEEGKINKYRYEFYIKTLEEIIEGEKNKW
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y066_AFV2P
Sequence: MSDVDDTIVDSIAIVGAILIGIFLIVVSVSNTSLFNNTEYDSMINSVLVIISSVIAYTLGKRRSKS
What are the official names of this protein?
Putative transmembrane protein ORF66.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: PURA_LACDA
Sequence: MTSIAVVGSQWGDEGKGKITDFLGTTADLSVRANGGNNAGHTIDFDGKEFKMRLIPSGIFAAKLGAVISNGVVINPKVLLGELNNLEKSGIDTSNLKISNRAHIIMPYHIMQDTYEEEAKGNLKVGTTKNGIGPTYMDKASRIGIRVCDLIDPETFAEKLRFNLERKNALFTKVYGKPAMDFDEIYNEYVEYGKRIAKYVCDTSLYVNDALDRNEKVLFEGAQGIMLDIDQGTYPFVSSSNSVSGGIASGSGIGANRIKTVLGICKAYTTRVGAGPFPTELHDETGDKIRDIAHEYGTVTGRPRRVGWFDSVALRHAKRVAGINALSLNLLDVFSGFDKIKICVAYDLNGKQIDYYPASLKEVEACQPIYEELPAWEEDITGAKSWEDLPEKAQAFVKRISEITGIPVVTVSVGPDREQTIVLQDPWTL
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCO1_PETHY
Sequence: MENFPIISLDKVNGVERAATMEMIKDACENWGFFELVNHGIPREVMDTVEKMTKGHYKKCMEQRFKELVASKALEGVQAEVTDMDWESTFFLKHLPISNISEVPDLDEEYREVMRDFAKRLEKLAEELLDLLCENLGLEKGYLKNAFYGSKGPNFGTKVSNYPPCPKPDLIKGLRAHTDAGGIILLFQDDKVSGLQLLKDGQWIDVPPMRHSIVVNLGDQLEVITNGKYKSVMHRVIAQKDGARMSLASFYNPGSDAVIYPAPALVEKEAEENKQVYPKFVFDDYMKLYAGLKFQAKEPRFEAMKAMETDVKMDPIATV
What are the official names of this protein?
1-aminocyclopropane-1-carboxylate oxidase 1, ACC oxidase 1, ACCO, Ethylene-forming enzyme, EFE.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.