PharMolix/UniProtQA huggingface dataset:
Protein: IF2_ECOSM
Sequence: MTDVTIKTLAAERQTSVERLVQQFADAGIRKSADDSVSAQEKQTLIDHLNQKNSGPDKLTLQRKTRSTLNIPGTGGKSKSVQIEVRKKRTFVKRDPQEAERLAAEEQAQREAEEQARREAEESAKREAQQKAEREAAEQAKREAAEQAKREAAEKDKVSNQQDDMTKNAQAEKARREQEAAELKRKAEEEARRKLEEEARRVAEEARRMAEENKWTDNAEPTEDSSDYHVTTSQHARQAEDESDREVEGGRGRGRNAKAARPKKGNKHAESKADREEARAAVRGGKGGKRKGSSLQQGFQKPAQAVNRDVVIGETITVGELANKMAVKGSQVIKAMMKLGAMATINQVIDQETAQLVAEEMGHKVILRRENELEEAVMSDRDTGAAAEPRAPVVTIMGHVDHGKTSLLDYIRSTKVASGEAGGITQHIGAYHVETENGMITFLDTPGHAAFTSMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAAQVPVVVAVNKIDKPEADPDRVKNELSQYGILPEEWGGESQFVHVSAKAGTGIDELLDAILLQAEVLELKAVRKGMASGAVIESFLDKGRGPVATVLVREGTLHKGDIVLCGFEYGRVRAMRNELGREVLEAGPSIPVEILGLSGVPAAGDEVTVVRDEKKAREVALYRQGKFREVKLARQQKSKLENMFANMTEGEVHEVNIVLKADVQGSVEAISDSLLKLSTDEVKVKIIGSGVGGITETDATLAAASNAILVGFNVRADASARKVIEAESLDLRYYSVIYNLIDEVKAAMSGMLSPELKQQIIGLAEVRDVFKSPKFGAIAGCMVTEGVVKRHNPIRVLRDNVVIYEGELESLRRFKDDVNEVRNGMECGIGVKNYNDVRTGDVIEVFEIIEIQRTIA
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAM_ECOSM
Sequence: MSDWNPSLYLHFAAERSRPAVELLARVPLENIKYVADLGCGPGNSTALLHQRWPAARITGVDSSPAMIAEARSALPDCQFVEADIRNWQPEQALDLIFANASLQWLPDHYELFPHLVSLLNSHGVLAVQMPDNWLEPTHVLMREVAWEQNYPDRGREPLAGVHAYYDILSEAGCEVDIWRTTYYHQMPSHQAIIDWVTATGLRPWLQDLTESEQQHFLTRYHQMLEEQYPLQENGEILLAFPRLFIVARRTE
What is the function of this protein?
Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
What are the official names of this protein?
Trans-aconitate 2-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Tam family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_VIBVY
Sequence: MRHYEIVFMVHPDQSEQVAGMIERYTGSITEAGGKIHRLEDWGRRQLAYPINKLHKAHYVLMNVEADQAVIDELETAFRYNDAVLRNMIMRTKAAITEPSIMLKQKEERAPRREAEAKEFAAE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: PROF7_MAIZE
Sequence: MSWQAYVDEHLMCEIEGHHLTSAAIVGHDGAVWAQSTAFPQFKTEEMTNIMKDFDEPGFLAPTGLFLGPTKYMVIQGEPGAVIRGKKGSGGITVKKTGQAMVVGIYDEPMTPGQCNMVVERLGDYLLEQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity).
What are the official names of this protein?
Profilin-7, Pollen allergen Zea m 12, Pollen profilin variant 2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: HBB_RABIT
Sequence: MVHLSSEEKSAVTALWGKVNVEEVGGEALGRLLVVYPWTQRFFESFGDLSSANAVMNNPKVKAHGKKVLAAFSEGLSHLDNLKGTFAKLSELHCDKLHVDPENFRLLGNVLVIVLSHHFGKEFTPQVQAAYQKVVAGVANALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta-1/2, Beta-1/2-globin, Hemoglobin beta-1/2 chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RS19_STRP8
Sequence: MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSFIGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: 5055R_ASFP4
Sequence: MFSLQEICRKNIYFLPDWLSEHVIQRLGLYWEKHGSLQRIGDDYVLIQQDLIIPINEALRMAGEEGNDEVVQLLLLWEGNIHYAIIGALEGDHYSLIRKLYDQIKDCHNILPLIQDPKTFEKCHELDESCNISCLVLHAVKNDMLCILQEYKMRLSGGDIQEVFETACRSQKYDIVTWMGENIAIYNPGVVFDIAFDLMNVSLLSIGYTLLFNHHINNMNENIDSLLAQHLEWAAGMGLLHFMLETLKYGGDVTITVLSEAVKYDHRKVLDYFLRRKNLYQEDLEELLLLAIRADCSKKTLNLLLSYLNYSINNIRKKILQCVKEYETTIIIKILWKRKINLIGPILADFIGYHSYTYMVDFMREFSIHPEKMIKMAARESREDLIIKFSKNVYKEPKDRLHYLKSLVYTMRHKEGKQLLIYTIHNLYKACHLESKEMFNLARFYARHNAVIQFKSICHDLSKLNINIKNLLLECLRIAIKKNYPQLIRTIKTDMSYE
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 505-5R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 505 family.
Protein: MUTH_SALTY
Sequence: MSALCPLLTPPASEALLLAQARQLSGYTLGELAAMAGITTPKDLKRDKGWIGVLLEIWLGASAGSKPEQDFAALGVELKTIPVDSLGRPLETTFVCVAPLTGNSGVTWETSHVRHKLKRVLWVPVEGDRSIPLAERRVGSPLLWSPSEEEDRQLRLDWEELMDMIVLGQVERITARHGEVLQLRPKAANARALTEAIGARGEPILTLPRGFYLKKNFTQALLARHFLLQNP
What is the function of this protein?
Sequence-specific endonuclease that cleaves unmethylated GATC sequences.  It is involved in DNA mismatch repair.
What are the official names of this protein?
DNA mismatch repair protein MutH, Methyl-directed mismatch repair protein.
What is the protein family that this protein belongs to?
Belongs to the MutH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IGS11_RAT
Sequence: MTRRRSALASWLLLSLLGVAASLEVSESPGSVQVARGQTAVLPCAFSTSAALLNLNVIWMVIPLSNANQPEQVILYQGGQMFDGALRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDRGGRNIGVTGLTVLVPPSAPNCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRSVGVIAGAVGTGAVLIVICLALTSGAFFYWRSKNKEEEEEEIPNEIREDDLPPKCSSAKAFHTEISSSENNTLTSSNTYNSRYWNNNPKPHKNTESFNHFSDLRQSFSGNAVIPSIYANGNHLVLGPHKTLVVTANRGSSPQVMPRNNGSVSRKPWSQHTHSYTVSQMTLERIGAVPVMVPAQSRAGSLV
What is the function of this protein?
Functions as a cell adhesion molecule through homophilic interaction.  Stimulates cell growth (By similarity).
What are the official names of this protein?
Immunoglobulin superfamily member 11, IgSF11.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: BL1S1_LACTC
Sequence: MSKASKEALLERALNKITKSQTNTNVAEAHEEIESNYAYINEKQLKRLVELHDTEFKDKCVVPLQRLYYKYSDTVLCDGDLQNWAELIDRDIRVLETTLAKVRDNQSGG
What is the function of this protein?
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1), a complex involved in endosomal cargo sorting.
What are the official names of this protein?
Biogenesis of lysosome-related organelles complex 1 subunit BLS1, BLOC-1 subunit BLS1, BLOS1-homolog.
What is the protein family that this protein belongs to?
Belongs to the BLOC1S1 family.
What are the subcellular locations of this protein?
Endosome.
Protein: RL6_MYCTA
Sequence: MSRIGKQPIPVPAGVDVTIEGQSISVKGPKGTLGLTVAEPIKVARNDDGAIVVTRPDDERRNRSLHGLSRTLVSNLVTGVTQGYTTKMEIFGVGYRVQLKGSNLEFALGYSHPVVIEAPEGITFAVQAPTKFTVSGIDKQKVGQIAANIRRLRRPDPYKGKGVRYEGEQIRRKVGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: MCR1_AJECN
Sequence: MFARYTFRCSQPLAQSVRKYSSEAPAKSSRIPLIGGITLAAGAGYYYYWQTTSAKSEPKERSTVFKGGDQGWIGLKLAHIDNVNHNVKKLRFEFEDPESVSGLHIASALLTKYKGLTDEKPTIRPYTPVSDEGMWASLGYLDLLVKRYPNGPMSNHLHNMAVGQRLDFKGPLPKYPWEPSKHDHICLIAGGTGITPMYQLVRKIFSNPEDKTKVTLVFANVTEEDILLRKEFEHLENTYPRRFRAFYTLDKPPKNWAQGTGFITKDLLKTVLPEPKTENIKIFVCGPPAMYKAISGQKVSPKDQGELSGILKELGYSKEQVYKF
What is the function of this protein?
May mediate the reduction of outer membrane cytochrome b5.
What are the official names of this protein?
NADH-cytochrome b5 reductase 2, Mitochondrial cytochrome b reductase.
What is the protein family that this protein belongs to?
Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: BIK1_YEAST
Sequence: MDRYQRKIGCFIQIPNLGRGQLKYVGPVDTKAGMFAGVDLLANIGKNDGSFMGKKYFQTEYPQSGLFIQLQKVASLIEKASISQTSRRTTMEPLSIPKNRSIVRLTNQFSPMDDPKSPTPMRSFRITSRHSGNQQSMDQEASDHHQQQEFGYDNREDRMEVDSILSSDRKANHNTTSDWKPDNGHMNDLNSSEVTIELREAQLTIEKLQRKQLHYKRLLDDQRMVLEEVQPTFDRYEATIQEREKEIDHLKQQLELERRQQAKQKQFFDAENEQLLAVVSQLHEEIKENEERNLSHNQPTGANEDVELLKKQLEQLRNIEDQFELHKTKWAKEREQLKMHNDSLSKEYQNLSKELFLTKPQDSSSEEVASLTKKLEEANEKIKQLEQAQAQTAVESLPIFDPPAPVDTTAGRQQWCEHCDTMGHNTAECPHHNPDNQQFF
What is the function of this protein?
Required for nuclear fusion, chromosome disjunction, and nuclear segregation during mitosis.  Probably required for the formation or stabilization of microtubules during mitosis and for spindle pole body fusion during conjugation.
What are the official names of this protein?
Nuclear fusion protein BIK1.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Cytoplasm, cytoskeleton, spindle. Cytoplasm. Note=And mitotic spindle.
Protein: PTYBC_ALIF1
Sequence: MAKITTSMIQEILTAIGGKSNVIKCGNCMTRLRLTLHDDNLADRDTIKRIAGVMGLVESDDQFQIVLGPGKAQTAAEMMNEMMEGEEDNSASTTAESRDLKDVASEHKQKLKKKQTSAAQRFLSKFATIFTPLIPGFIAAGLLLGFATLLDQIYIIGNESPNANLVDLILYMKVFSKGLFSFLSILIGYNAQQAFGGSGVNGAILASLFVLGYNPDATSGIYSGMTDFFGHGIDPRGNIIGVLIAAIIGAGVEKKVRQYMPDNLDMILTSVVTLLIMGAVTFVVIMPIGGVLFQGMSWLFMNLNGNPIGSAILAGLFLISVMFGIHQGFVPVYFALMDAQGFNSLFPILAMAGAGQVGAALALYAKANKDALLRTQVKGSIIPGFLGIGEPLIYGVTLPRVKPFITACVGGAAGGFFIGLVSYMGLPVGLNTVFGPSGIVALPLMTSNAGIFAGMLVFAAGLVISYVAGFLATWFFGTKNVDLS
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  This system is involved in N-acetylmuramic acid (MurNAc) transport, yielding cytoplasmic MurNAc-6-P.  Is also able to take up anhydro-N-acetylmuramic acid (anhMurNAc), but cannot phosphorylate the carbon 6, probably because of the 1,6-anhydro ring.
What are the official names of this protein?
PTS system N-acetylmuramic acid-specific EIIBC component, EIIBC-MurNAc.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYY_AERPE
Sequence: MVRVDVEERFNRIARNTVEIVTEEELKGLLASGARIKGYIGYEPSGVAHIGWLVWMYKVKDLVEAGVDFSVLEATWHAYINDKLGGDMDLIRAAARIVRRVMEAAGVPVERVRFVDAEELASDKDYWGLVIRVAKRASLARVRRALTIMGRRAEEAEVDASKLIYPLMQVSDIFYMDLDIALGGMDQRKAHMLARDVAEKLGRKKPVAIHTPIISSLQGPGRMEASQGEIDDVLAEVKMSKSKPETAVFVVDSDDDIRRKIRKAYCPAKQVQGNPVLEIARYILFARDGFTLRVDRPAKYGGPVEYTSYEELERDYTDGRLHPLDLKNAVAESLIEVVRPIRGAVLGDPAMKRALEAIEGKVTR
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIPK3_MOUSE
Sequence: MASQVLVYPPYVYQTQSSAFCSVKKLKVEPSGCVFQERTYPQIHVNGRNFGNSHPSTKGSAFQTKIPFTKPRGHSFSLQAGAIVVKDTAGATKVLAAQAQQAGVEAPRAVVWRNRLHFLEGPQRCGLKRKSEELENHSGAMQIVDELSILPAMLQTNMGNPVTVVTATTGSKQNCTSGEGDYQLVQHEVLCSMKNTYEVLDFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTENADEYNFVRAYECFQHRNHTCLVFEMLEQNLYDFLKQNKFSPLPLKVIRPVLQQVATALKKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGALEYDQIRYISQTQGLPGEQLLNVGTKSTRFFCRETDMSHSGWRLKTLEEHEAETGMKSKEARKYIFNSLDDIVHVNTVMDLEGGDLLAEKADRREFVNLLKKMLLIDADLRITPIETLNHPFVNMKHLLDFPHSNHVKSCFHIMDICKSPSSCETNNHSKMSLLRPVASNGTAALAANFTKVGTLRSQALTTSAHSVVHHGIPLQAGTAQFGCGDAFHQTLIICPPAIQGIPAAHGKPTSYSIRVDNTVPLVTQAPAVQPLQIRPGVLSQQTWSGRTQQMLIPAWQQVTPMAPAAATLTSEGMAGSQRLGDWGKMIPHSNHYNSVMPPPLLTNQITLSAPQPISVGIAHVVWPQPATTKKNKLCQNRSNSLQNTNIPHSAFISPKIISGKEVEEVSCVDTQDNHTSEGEAGTCREASVRQDSSVSDKQRQTIIIADSPSPAVSVITISSDSDDEETSPRPSLRECKGSLDCEACQSTLNIDRMCSLSSPDSTLSTSSSGQSSPSPCKRPNSMSDDEQESGCETVDGSPTSDSSGHDSPFAENSFVEDAHQNTELGTCAGPEAKPAVGTAVEPPVGRESGLSVDEHMANTDSTCQPLRKGQPAPGKLHQPPALGARQQKPAAAFPQQHLNLSQVQHFGTGHQEWNGNFGHRRQQAYIPTSVTSNPFTLSHGSPNHTAVHAHLAGSTHLGGQPTLLPYPSSASLSSAAPVAHLLASPCTSRPMLQHPTYNISHPSGIVHQVPVGINPRLLPSPTIHQTQYKPIFPPHSYIAASPAYTGFPLSPTKLSQYPYM
What is the function of this protein?
Serine/threonine-protein kinase involved in transcription regulation, apoptosis and steroidogenic gene expression.  Phosphorylates JUN and RUNX2.  Seems to negatively regulate apoptosis by promoting FADD phosphorylation.  Enhances androgen receptor-mediated transcription.  May act as a transcriptional corepressor for NK homeodomain transcription factors.  The phosphorylation of NR5A1 activates SF1 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.  In osteoblasts, supports transcription activation: phosphorylates RUNX2 that synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE).
What are the official names of this protein?
Homeodomain-interacting protein kinase 3, Androgen receptor-interacting nuclear protein kinase, ANPK, Fas-interacting serine/threonine-protein kinase, FIST, Nuclear body-associated kinase 3, Nbak3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. HIPK subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TRPA_MARSD
Sequence: MSITKLADKINEAKAEGRLGLIPFLPGGYPNRDQFWKEILELDEHGADVIEIGMPFSDPVADGPVVEAASLKCLEDGINLKWILAGLSEHRAKISAGVLLMGYYNPVLQYGLEEFAKDASAAGVNGLIIADLPYEEGVEFRDLLAKYDIALIPLVGLNTEADRMALYSKGGNGFCYYVSVLGTTGGTATLPEEIKQGLAKAQEVFDIPVALGFGLKEPSQLKELEGLVDAAVFGSALIKHIDSGKSSAEFMKVWK
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: SYL_BRASB
Sequence: MTSERYNAREAEPRWQRQWDEKAIFATKNDDPRPKYYVLEMFPYPSGRIHIGHVRNYTLGDVLARFMRAKGFNVLHPMGWDAFGLPAENAAIERKVAPKAWTYDNIAAMKKQLRSIGLSLDWAREFATCDPSYYKHQQKMFLDFMQAGLVEREQRKVNWDPVDMTVLANEQVIDGRGWRSGAVVEQREMNQWVFKITKYSQELLDALDGLDRWPDKVRLMQRNWIGRSEGLLIRFALDPQTTPAGETELKIFTTRPDTLFGAKFMAISADHPLAQAAAAKNPELAAFIAEIKRIGTAQEAIDTAEKQGFDTGIRAVHPFDPSWTLPVYVANFVLMEYGTGAIFGCPAHDQRDLDFVNKYGLGNTPVVCPEGQDPASFVITDTAFDGDGRLINSRFLDGMTIAQAKDEVAKRLEAEQRGGAAVGERQVNFRLRDWGISRQRYWGCPIPVIHCPTCDVVPVPAKDLPVVLPDDVTFDKPGNALDHHPTWKHVTCPKCGGKATRETDTMDTFVDSSWYFARFTDPWNETAPTTPDVANRMMPVDQYIGGVEHAILHLLYSRFFTRAMKATGHVAMDEPFAGMFTQGMVVHETYQKADGTYVNPAEVKIEVGGNGRRAVLTATGEDITIGPIEKMSKSKKNTVDPDDIIESYGADVARWFMLSDSPPDRDVIWSDERVQGAARFVQRLWRLVNESVAAGQEAPSSRPATFGPDALALRKAAHGALDKVTGGIERLHFNVCLAHIREFANALAEVLARPAKPAPDLAWAIREAAQILVQLFSPMMPHLAEECWQVLGQGGLISEASWPQIERDLLVEDSVTLVVQVNGKKRGEVTVASNAQNPEIESAVLALDAVKLALDGKPVRKVIIVPKRIVNVVG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_RALSO
Sequence: MASGKIAAFRDFSAAAMPNVLRLTDLISEGKLAGKRVFIRADLNVPQDDAGNITEDTRIRASVPAIRAALDAGAAVMVTSHLGRPTEGEFKPEDSLAPVAVRLSELLGCEVKLVQNWVDGVDVAPGQVVLLENCRVNKGEKKNSDELAQKMAKLCDVYVNDAFGTAHRAEATTHGIAKFAPIACAGPLLGAELDALGKALGQPARPLVAIVAGSKVSTKLTILKSLADKVDNLIVGGGIANTFMLAAGLKIGKSLAEADLVGDAKAIIDLMAARGASVPIPVDVVCAKEFSATAAATVKDVKDVADDDMILDIGPKTAAQLADQLKASGTIVWNGPVGVFEFDQFGNGTKVLAEAIAASSGFSIAGGGDTLAAIAKYGIADRVGYISTGGGAFLEFLEGKTLPAVEILEQRAQRQEALA
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_RHOP2
Sequence: MSTTKRCYYETLEVERSADESTLKSAFRKLAMKWHPDRNPGDASSEIKFKEINEAYEVLKDGDKRAAYDRYGHAAFEQGMGGGGPGFGAGFASSFSDIFEDLFGMAGQRGRGTGRERGADLRYNMEITLEDAYKGKTAQIEIPVSVTCESCSGTGAKAGTKPKTCSTCGGAGRVRQAQGFFTLERTCPSCQGRGQIIEDPCPSCTGSGRVTKERTLSVNIPQGVEDGTRIRLAGEGEAGVRGGPPGDLYIFLSLASHAIFQRDGADLHCRVPISMVTAALGGEFEVPTIERGKTKVKVPSGTQTGRRFRIAGKGMPVLRSRQVGDMYVQVAVETPQNLTKKQQELLAEFEKLSSGATQPEAAGFFSKVKDFFGSRANTP
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KMO_LEGPL
Sequence: MKHITIIGAGLAGTLCGLYLARRGYEVELFESRPDIRNSPTDYGRSINLALSCRGITALKAMNLLSEVNKIMVPMRARAIHEANGEIHYQPFGRHIDEYINAISRSDLNALLLNKAKLCPNIKLHFNMKLHSLDIHNKKIKFENKNGDFVEASYHRLIGADGAPSHVRDMLKNEGIVSASRDFLSHGYKELSISKKHTKGMAREHLHLWPRDSFMLLGNPNPDDSITGSLFLANEGKDSFAELNNEEKLHLFFKTQFPDAYAAMPNLVQEFFGNPTGHLSTIQCSPWYYKDECLLIGDAAHGIIPFFGQGMNSAFEDCRILDELLDEYQDDWSRVNSVFYEHRKVNTDAIAKMSMDNYHEIHSDIRNPKFILQKQIERELMLRYPEHYVSMHVLVMFTNTPYAKAMAIGELQSGLLEQICFPITDIKELNWQEVEKLLSLYDKKLAKII
What is the function of this protein?
Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn).  Required for synthesis of quinolinic acid.
What are the official names of this protein?
Kynurenine 3-monooxygenase, Kynurenine 3-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
Protein: ARGC_RHOCB
Sequence: MTQKIAILGASGYTGAELARIIATHPEMEITALSGDRKAGMRMGEVFPHLRHIGLPDLVKIEEIDFSGIDLAFCALPHATSQAVIAELPRDLKVVDLSADFRLRDAAEYEKWYGKPHAAMDLQAEAVYGLTEFYREELKTARLCAGTGCNAAAGQYAIRPLIEAGVIDLDEIVIDLKAGVSGAGRSLKENLLHAELAGGTMPYSAGGKHRHLGEFDQEFSKVAGRPVRVQFTPHLMPFNRGILATVYVRGTPEDIHAALASRYENEVFLEVLPFGQLASTRSVAGSNFVHLGVIGDRLPGRAVVTVALDNLTKGSSGQAIQNANLMLGLPETLGLMLAPVFP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_STRPJ
Sequence: MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKDMQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQAEAVADYKHQASLKSDLVRTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGTGAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDAIAKIVACLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLVLPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHIETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALDKAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHLAEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREELQEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TES_HORSE
Sequence: MDLETKVKKMGLGHGQGFGAPCLKCKEKCEGFELHFWRKICRNCKCGQEEHDVLLSNEEDRKVGKLFEDTKYTTLIAKLKSDGIPMYKRNVMILTNPVAAKKNISINTVTYEWAPPVQNQALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPKEVKEMEQFVKKYKNEALGVGDVKLPREMDAQDPNRMCIPGGDRSTTAAVGAKENKLAENKRTQYSCYCCNLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNGKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKKMMS
What is the function of this protein?
Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton.  Plays a role in the regulation of cell proliferation.  May act as a tumor suppressor (By similarity).
What are the official names of this protein?
Testin.
What is the protein family that this protein belongs to?
Belongs to the prickle / espinas / testin family.
What are the subcellular locations of this protein?
Cytoplasm. Cell junction, focal adhesion. Note=Detected along actin stress fibers.
Protein: IL4_BOVIN
Sequence: MGLTSQLIPVLVCLLVCTSHFVHGHKCDITLAEIIKTLNILTTRKNSCMELPVADVFAAPKNTTEKETFCRVGIELRRIYRSHTCLNKFLGGLDRNLNSLASKTCSVNEAKTSTSTLKDLLERLKTIMKEKYSKC
What is the function of this protein?
Participates in at least several B-cell activation processes as well as of other cell types.  It is a costimulator of DNA-synthesis.  It induces the expression of class II MHC molecules on resting B-cells.  It enhances both secretion and cell surface expression of IgE and IgG1.  It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.  Positively regulates IL31RA expression in macrophages.  Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4.
What are the official names of this protein?
Interleukin-4, IL-4, B-cell stimulatory factor 1, BSF-1, Lymphocyte stimulatory factor 1.
What is the protein family that this protein belongs to?
Belongs to the IL-4/IL-13 family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y100_UREU1
Sequence: MDFQKLAQELKKMQNTLSKKQKEFEEKVFDFDYKGYVLIKIKGNLTIESIEVKTEIVDPEDKETLQDILRAAVNEAISKTCKERDAIMNSTIPKGTGFF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein UUR10_0100.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.