PharMolix/UniProtQA huggingface dataset:
Protein: NU2C2_NUPAD
Sequence: MIWHVQNENFILDSTRIFMKAFHLLLFNGSFIFPECILIFGLILLLMIDSTSDQKDTPWLYFISSTSLVMSITALLFRWREEPMISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDLITIFVAPECFSLCSYLLSGYTKRDVRSNEATTKYLLMGGASSSILVYGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALISITVGIGFKLSPAPFHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNDGYASMITYMLFYISMNLGTFACIVLFGLRTGTDNIRDYAGLYTKDPFSALSSALCLLSLGGIPPLAGFFGKLYLFWCGWQAGLYFLVSIGLLTSVVSIYYYLKIIKLLMTGRNKEITPHVRNYRRSPLRSNNSIELSMIVCVIASTIPGISMNPIIAIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 B, chloroplastic, NAD(P)H dehydrogenase, subunit 2 B, NADH-plastoquinone oxidoreductase subunit 2 B.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: SCP34_ARATH
Sequence: MGSHSVEFSVLVLFLVSFLLGSTSAEKLCSDNDGDNGCFRSRVLAAQRADRVKELPGQPPVKFRQYAGYVTVNETHGRALFYWFFEATQNPSKKPVLLWLNGGPGCSSIGFGAAEELGPFFPQNSSQPKLKLNPYSWNKAANLLFLESPVGVGFSYTNTSRDIKQLGDTVTARDSYNFLVNWFKRFPQYKSHDFYIAGESYAGHYVPQLSELIYKENKIASKKDFINLKGLMIGNALLDDETDQKGMIEYAWDHAVISDALYEKVNKNCDFKQKLVTKECNDALDEYFDVYKILDMYSLYAPKCVPTSTNSSTSHSVAGNRPLPAFRSILRPRLISHNEGWRRMAAGYDPCASEYTEKYMNRKDVQEALHANVTNISYPWTHCSDTVSFWSDAPASMLPTLRTLVSAGLRVWVFSGDTDGRIPVTATRYSLKKLGLKIVQDWTPWYTKLQVGGWTVEYDGLMFVTVRGAGHQVPTFKPREALQLIHHFLGNKKLPTFPF
What is the function of this protein?
Probable carboxypeptidase.
What are the official names of this protein?
Serine carboxypeptidase-like 34.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Secreted.
Protein: IKZF1_MOUSE
Sequence: MDVDEGQDMSQVSGKESPPVSDTPDEGDEPMPVPEDLSTTSGAQQNSKSDRGMGSNVKVETQSDEENGRACEMNGEECAEDLRMLDASGEKMNGSHRDQGSSALSGVGGIRLPNGKLKCDICGIVCIGPNVLMVHKRSHTERPFQCNQCGASFTQKGNLLRHIKLHSGEKPFKCHLCNYACRRRDALTGHLRTHSVGKPHKCGYCGRSYKQRSSLEEHKERCHNYLESMGLPGVCPVIKEETNHNEMAEDLCKIGAERSLVLDRLASNVAKRKSSMPQKFLGDKCLSDMPYDSANYEKEDMMTSHVMDQAINNAINYLGAESLRPLVQTPPGSSEVVPVISSMYQLHKPPSDGPPRSNHSAQDAVDNLLLLSKAKSVSSEREASPSNSCQDSTDTESNAEEQRSGLIYLTNHINPHARNGLALKEEQRAYEVLRAASENSQDAFRVVSTSGEQLKVYKCEHCRVLFLDHVMYTIHMGCHGCHGFRDPFECNMCGYHSQDRYEFSSHITRGEHRYHLS
What is the function of this protein?
Transcription regulator of hematopoietic cell differentiation.  Binds gamma-satellite DNA.  Binds with higher affinity to gamma satellite A.  Plays a role in the development of lymphocytes, B- and T-cells.  Binds and activates the enhancer (delta-A element) of the CD3-delta gene.  Repressor of the TDT (terminal deoxynucleotidyltransferase) gene during thymocyte differentiation.  Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes.  Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus in adult erythrocytes.  Increases normal apoptosis in adult erythroid cells (By similarity).  Confers early temporal competence to retinal progenitor cells (RPCs).  Function is isoform-specific and is modulated by dominant-negative inactive isoforms (By similarity).
What are the official names of this protein?
DNA-binding protein Ikaros, Ikaros family zinc finger protein 1, Lymphoid transcription factor LyF-1.
What is the protein family that this protein belongs to?
Belongs to the Ikaros C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Note=In resting lymphocytes, distributed diffusely throughout the nucleus. Localizes to pericentromeric heterochromatin in proliferating cells. This localization requires DNA binding which is regulated by phosphorylation / dephosphorylation events. SUBCELLULAR LOCATION: [Isoform V]: Nucleus. Note=In resting lymphocytes, distributed diffusely throughout the nucleus. Localizes to pericentromeric heterochromatin in proliferating cells. This localization requires DNA binding which is regulated by phosphorylation / dephosphorylation events. SUBCELLULAR LOCATION: [Isoform I]: Cytoplasm.
Protein: SUCC_RICBR
Sequence: MNIHEYQAKEILRKYGVPTSTGVVVTKTESINAAIDELNTKVYVVKAQIHAGGRGKAGGVKVVKSKEEAKKVAHDMFGINLVTHQTGPQGQKVNRLYIESGCDILKEYYFSVVFDRSASCITFIASTEGGVDIEEVAEKTPEKIIKFSVDPATGLQNFHAQGIAYELGFKDHQVKQMKEIVKATYKAFIETDAAQIEINPLIVNKEGNLLALDAKFTFDDNGLFKHPEIMALRDQDEEDPLETRAADAGLSYVKMDGSIGCMVNGAGLAMATMDIIKLYGATPANFLDVGGGADRERVKEALKIILSDKEVKGILVNIFGGIMRCDIIAEGIIAAAKDIGIKVPLVVRLAGTNVEKGKEILSNSGLEIIPAHDLADAASKIVEAI
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: HEMH_LEGPL
Sequence: MRRGLLLLNLGTPDNADIRAVKLYLREFLTDKRVIDLPTIPRYILVYCLILPFRSPKSAQAYQSIWTEKGSPLLYHSQNLVTKLQSALKDEYKIALGMRYGTPSITTALAELKDCHSLTILPLFPQYSSAATGSAIEKTLSYLANQEIIPSIKIIRDFYQRPEYIQAQAKIMKPYIKDNFHVLFSYHGIPERHIHKSGCDTLCPQTCTPIYDKNQACYRAQCYQTSLLLAKELQLGTHQYTTAFQSRLGKTPWIKPYTDEIFAELISKGIKNIVVSCPSFVADCLETLEEIGIRAKEQWEKLGGEQFILTPCMNDHPEWIKAIQSIVNEQF
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ESXB_MYCTU
Sequence: MAEMKTDAATLAQEAGNFERISGDLKTQIDQVESTAGSLQGQWRGAAGTAAQAAVVRFQEAANKQKQELDEISTNIRQAGVQYSRADEEQQQALSSQMGF
What is the function of this protein?
A secreted protein.  Acts as a strong host (human) T-cell antigen (PubMed:11940590).  Involved in translocation of bacteria from the host (human) phagolysosome to the host cytoplasm (PubMed:17604718).  Might serve as a chaperone to prevent uncontrolled membrane lysis by its partner EsxA; native protein binds poorly to artificial liposomes in the absence or presence of EsxA (PubMed:17557817, PubMed:26260636).  EsxA and EsxA-EsxB are cytotoxic to pneumocytes (PubMed:19906174).  EsxB (and EsxA-EsxB but not EsxA alone) activates human neutrophils; EsxB transiently induces host (human) intracellular Ca(2+) mobility in a dose-dependent manner, monocytes and lymphocytes do not respond (PubMed:25332123).  Neutrophils respond to EsxB by chemotaxis and primed neutrophils treated with EsxB produce reactive oxygen species (ROS); Ca(2+) release and the ROS burst via are induced by an unidentified G-protein coupled receptor (PubMed:25332123).  May help regulate assembly and function of the type VII secretion system (T7SS) (PubMed:25865481).
What are the official names of this protein?
ESAT-6-like protein EsxB, 10 kDa culture filtrate antigen CFP-10, CFP-10, Secreted antigenic protein MTSA-10.
What is the protein family that this protein belongs to?
Belongs to the WXG100 family. CFP-10 subfamily.
What are the subcellular locations of this protein?
Secreted. Secreted, cell wall. Host cell surface. Host endoplasmic reticulum. Note=Probably secreted via the ESX-1 / type VII secretion system (T7SS) (PubMed:19876390). Binds to CD14+ and CD19+ host (human) cells (PubMed:19265145). Localized on the cell surface of host (human) cell monocytes and macrophages (often in patches), but not fibroblasts (PubMed:15973432). Exogenous EsxA and EsxA-EsxB complex can enter host (human and mouse) endoplasmic reticulum (PubMed:25356553).
Protein: NU2M_RAT
Sequence: MNPITLIIIYFTILMGPVITMSSSNLLLMWVGLEMSLLAIIPLLANKKSPRSTEAATKYFLTQATASMIILLVIILNYKQSGMWTLQQQTNNMLLNMMLISLAMKLGLAPFHYWLPEVTQGIPLHIGLILLTWQKIAPLSILYQFYQLLNPTITTILAISSVFVGAWGGLNQTQTRKIMAYSSIAHMGWMTAILPYNPNLTLLNLTIYILLTVPMFITLMTNSATTINTLSLAWNKTPMILTMTSIILLSLGGLPPLTGFLPKWAIISELLKNNCSTLSTLMAIMALLSLFFYTRLIYSMSLTMFPTNNNSKMISHHHQNPKHNFILPTLTVLSTLTLPLSSQLIT
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: LEU1_METNO
Sequence: MTETAASSAERVLIFDTTLRDGEQCPGATMTFEEKLAVAEMLDGMGVDIIEAGFPIASNGDFDAVAEIARRTKTSVVAGLARAISADIARAGEAVRLAKRGRIHTFVSTSPIHLAHQMRKSEEEVLEIIQKTVAQARDLVEDVEWSAMDATRTPIDYLCRCVEMAIKMGATTINLPDTVGYATPDEYRAMFRSVRERVPNADRAIFSVHCHNDLGLAIANSLAGIEGGARQVECTINGIGERAGNAALEEVVMALRTRADVLPYTTGIDTTQIMRASKLVAAATHFPVQYNKAVVGRNAFAHESGIHQDGMLKNQSTYEIMTPESVGVQKTSLVMGKHSGRAAFRSKLEELGYRLSDNQFQDAFERFKALADRKKNVYDEDIEALVDENLATAHDRIRLLSLTVIAGTRGPQRATMRLDIDGRQATEEADGNGPVDAVFNAIHALVPHEAKLELYDVHAVTEGTDAQAEVSVRLRQGERSVTARGADPDTLVASAKAYLAALNKLLAGANRLHAQHAAAE
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: MES3_ARATH
Sequence: MSEEERKQHVVLVHGACHGAWCWYKVKPQLEASGHRVTAVDLAASGIDMTRSITDISTCEQYSEPLMQLMTSLPDDEKVVLVGHSLGGLSLAMAMDMFPTKISVSVFVTAMMPDTKHSPSFVWDKLRKETSREEWLDTVFTSEKPDFPSEFWIFGPEFMAKNLYQLSPVQDLELAKMLVRANPLIKKDMAERRSFSEEGYGSVTRIFIVCGKDLVSPEDYQRSMISNFPPKEVMEIKDADHMPMFSKPQQLCALLLEIANKYA
What is the function of this protein?
Methylesterase shown to have carboxylesterase activity, methyl indole-3-acetic acid (MeIAA) esterase activity and methyl jasmonate (MeJA) esterase activity in vitro.
What are the official names of this protein?
Methylesterase 3, AtMES3.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Methylesterase family.
Protein: COX7A_DROME
Sequence: MMNLSRAVVRSFATTAGRRSAAVPKDQIEKGYFEIRKVQEHFQKKDGKPVFLKGSVVDNVLYRVTVALALVGIGGMGKLFYELSVPKKE
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 7A, mitochondrial, Cytochrome c oxidase subunit VIIa.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase VIIa family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: RK5_EMIHU
Sequence: MKKDTKNLYKEKIVPSLMEEYGYKNVQLVPKLLKISINRGLGEEARSSKEMDANLKELAVIAGQQPTVNKARKSIAGFKIRDGMPVGASVTLRQDRMYAFLERLIHITLPRVRDFRGISAEGFDGRGNYNLGIKDQLIFPEISYDDVNQLQGFDISIVTSANTDEEAYSLLKKFGMPLQARA
What is the function of this protein?
Binds 5S rRNA, forms part of the central protuberance of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L5, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CTXL_ACRMI
Sequence: RWLGWQKFCWISCLFSSISSGLDPGEQAKVTTALDTAQFAINAINEEYIAQAKAIEEALKVSTQARSADLLRRQTELAKFGSKVGKALKAVQAASAIASFVFTFFMPSELDVITSLINERFNEVNAKLDRIDEKLDEMEKSIKADTAFNVFLSAWIKWEYKVRNGAKKLSDIRKAMGTKTQRIDQVKLAEEYVKYYETNNLDGNVLSLYRMAALPESITQRNIFDRFIAQFGCDITKLSELMILVQNIMTSAGQQKLTYYYFKGDQSRANSSFKDIQMYFFKIRQGFDDRVWHCRRNSLDYAKRDANKILKNMRGSSRESIVRAIFNELKVKYPWYTWAVAAVKSDRPRIRGLELRGSTYFRLEDRSDAKKVKGYFVVYEDTRSSASCSDITQAKTLLVFKKCDGCNSDYIYAADNILSKKRCGESTLERLVDFKQQCPVCHRWPYSITCYCANRVKQDSQNMGLYCISSQHH
What are the official names of this protein?
Cephalotoxin-like protein.
What are the subcellular locations of this protein?
Secreted.
Protein: MCRA_METTE
Sequence: AADIFAKFKTSMEVK
What is the function of this protein?
Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2-(methylthio)ethanesulfonate) using coenzyme B (CoB or 7-mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB).  This is the final step in methanogenesis.
What are the official names of this protein?
Methyl-coenzyme M reductase subunit alpha, Coenzyme-B sulfoethylthiotransferase alpha.
What is the protein family that this protein belongs to?
Belongs to the methyl-coenzyme M reductase alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F16PA_BURTA
Sequence: MSITRRTTLSKYLIEQQRETHNLPADLRLLIEVVARACKAISYNVSKGALGDALGTAGSENVQGEVQKKLDILSNEILLDANEWGGNLAAMASEEMETFFPIPANYPRGEYLLVFDPLDGSSNIDVNVSIGTIFSVLRCPDGQQATEQSFLQPGTEQVAAGYAVYGPQTVFVLTTGNGVNCFTLDREVGSWVLTQSNLRIPEDTREYAINASNARHWYDPVKRYVDELNAGAEGPRGENFNMRWIASMVADVHRILNRGGIFMYPADKRTPDRPGKLRLMYEANPMSFIVEQAGGAATTGLKRILDVQPTGLHQRVPVILGSKNEVERVARYHQEAQS
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOC_CALS4
Sequence: MLKKEESLMNIAKMIDHTLLKPNATKEEIKKVCEEAREYGFASVCINPCFVDLAYEMLKDTDVKVCTVVGFPLGANTIETKVVEAVEAVKKGATEIDMVLNISMLKSGEYDYVKKEIGEVVKAVKSHGDIVVKVILETCYLSDEEKIKACEISKEAGADFVKTSTGFGPGGATVEDVKLMRKVVGENFGVKASGGIRSYEDAKAMIEAGANRIGASAGVKIVEEWKKQGLG
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YES_CHICK
Sequence: MGCIKSKEDKGPAMKYRTDNTPEPISSHVSHYGSDSSQATQSPAIKGSAVNFNSHSMTPFGGPSGMTPFGGASSSFSAVPSPYPSTLTGGVTVFVALYDYEARTTDDLSFKKGERFQIINNTEGDWWEARSIATGKTGYIPSNYVAPADSIQAEEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDWDEVRGDNVKHYKIRKLDNGGYYITTRAQFESLQKLVKHYREHADGLCHKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMMPEAFLQEAQIMKKLRHDKLVPLYAVVSEEPIYIVTEFMTKGSLLDFLKEGEGKFLKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGDNLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMVNREVLEQVERGYRMPCPQGCPESLHELMKLCWKKDPDERPTFEYIQSFLEDYFTATEPQYQPGDNL
What is the function of this protein?
Non-receptor protein tyrosine kinase that is involved in the regulation of cell growth and survival, apoptosis, cell-cell adhesion, cytoskeleton remodeling, differentiation, G2/M progression and cytokinesis.
What are the official names of this protein?
Tyrosine-protein kinase Yes, p61-Yes.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytosol.
Protein: ISPH_CHLTA
Sequence: MRKIILCSPRGFCAGVIRAIQTVEVALEKWGRPIYVKHEIVHNRHVVDKLREKGAIFIEDLQEVPRNSRVIFSAHGVPPSVREEAAERGLIAIDATCGLVTKVHSAVKMYAKKGYHIILIGKRKHVEIIGIRGEAPDQITVVENIAEVEALPFSAQDPLFYVTQTTLSMDDAADIVAALKARYPRIFTLPSSSICYATQNRQGALRNILPQVDFVYVIGDSQSSNSNRLREVAERRGVTARLVNHPDEVTEEILQYSGNIGITAGASTPEDVVQACLMKLQELIPDLSIEMDLFVEEDTVFQLPKEL
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: Y1201_ARCFU
Sequence: MQLCSWNLRGSEQRFHPTTSCVDYYLRIEFKKLFELCKIMKNMKTKMVRLGTYVSQDAYKLLRELTELYGNQSNVLDQAIRLLYDVSKYGSKADRILIREKLINEFENILISKKNFMHLLEGKKEGLFDEDVITAVILSFVDESMDSKSFFPKMMDALKKIYVEGNRWFTNIEYKETESGYKVTFYHNLNSEFSDFASEYFRRFFKIGYKIVEEQKLNKLFILQVSEF
What are the official names of this protein?
Uncharacterized protein AF_1201.
Protein: YQGF_DEHMC
Sequence: MGDKWIGAALSDPLRILASPLVILRRDDDTKTLENIESLVKTHQPDLLIIGLPISLNGTIGPQAEKVKSFSELLSRHLNIEIIYRDERFSTDEARRKMNDSGKNNKTVRDDAAAAAVILQDYLDETNPPCCQP
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_CALS8
Sequence: MEQKRGMRKTRIGVVVSDKMDKTVVVAVETLVQHPLYKKTIKRTTKFKAHDENNECRVGDKVLIMETRPLSKEKRWRVVQILERAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: GPI14_ASPFU
Sequence: MTSFFDSPSKVIGASIALRAVLLVYGAWQDAHSPIKYTDIDYFVFTDAARYVSRGASPYARDTYRYTPLLAWLLLPTTWDSIPGFFAFGKALFALADVVAGWLIAKVLVSAYGMSPSRALKYASVWLLNPMVANISTRGSSEGLLGVLVVGLLWAVLSRRVSLAGVILGLGVHFKIYPFIYGPAVVWWFDAERDGSGSPRGTATARAAREKDDGQDGQGILSKAVDFLTPARIHLTLVALATFSALNVSMYILYDLPFAQNTYLHHLTRIDHRHNFSPYSTLLYLSAAGGARTAFESLAFIPQLLLSVVVIPLVLGKKSLAGTMLAQTFAFVTFNKVCTSQYFLWYLIFLPFYLPSSSLMKNPRKGILVGLLWVIAQALWLQQGYNLEFLGLSSFVPGLFLASLFFFAVNVWILGIIVEDVGGSA
What is the function of this protein?
Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.  Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly.  Required for cell wall integrity (By similarity).
What are the official names of this protein?
GPI mannosyltransferase 1, GPI mannosyltransferase I, GPI-MT-I, Glycosylphosphatidylinositol-anchor biosynthesis protein 14.
What is the protein family that this protein belongs to?
Belongs to the PIGM family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MYADM_RAT
Sequence: MPVTVTRTTITTTSSSSTTVGSARALTQPLGLLRLLQLVSTCVAFSLVASVGAWTGPMGNWAMFTWCFCFAVTLIILIEELGGFQARFPLSWRNFPITFACYAALFCLSSSIIYPTTYVQFLPHGRSRDHAIAATTFSCVACLAYATEVAWTRARPGEITGYMATVPGLLKVFETFVACIIFAFISEPSLYQQRPALEWCVAVYAICFILAAVTVLLNLGDCTNMLPIPFPTFLSGLALLSVLLYATAIVLWPLYQFDQRYNSQPRRSMDPSCSRSYVQPNEVCNWDRRLAVSILTGINLLAYVSDLVYSTRLVFVKV
What are the official names of this protein?
Myeloid-associated differentiation marker, Myeloid up-regulated protein.
What is the protein family that this protein belongs to?
Belongs to the MAL family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SAM_RICFE
Sequence: MNDALKTYLTGIGWFLLSLVSSSANDVMSKYLGTRLHSFEVAFFRFFFSSIVLLPFVFYHGKNTLKTSRPFVHILRGLLLFFGMTSWTYGLTIAPVTTATVVSFSIPLFTLILAVFFLNENIIWQRWVVTVVGFIGLVVTLKPHTEDFNPEILYFVLAAISFAMLDIINKKFVIKESMISMLFYSAIVTAVVSLPVASQYWLTPSGFELALLFVLGSSGSLILFFLLKAFSMVDATATAPYRYLELVISAIAAYFIFSEFPDKSTLHGAVIIIPATLFIIYSEKKAMSRKHESQ
What is the function of this protein?
Transports S-adenosylmethionine.
What are the official names of this protein?
S-adenosylmethionine uptake transporter.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. 10 TMS drug/metabolite exporter (DME) (TC 2.A.7.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ENO_BUCAP
Sequence: MSKILKIIGREIIDSRGNPTIECEVLLEGGFVGLASVPSGASTGSFETWELRDQDKNRFMGKGVQKAVEIINNKIFYSLKNKNAIDQFDIDQTMINLDGTENKSNLGSNSILSVSLATAKAAASSKGMPLYQHIAEINNTPGVFSMPLPMINIINGGKHANNNIDIQEFMIQPISAKSITEAIRIGAEIFHSLGNLLKDKGMSTTVGDEGGYAPNFKSNEEALNVIQDAVHKTKYKLGKDITLAIDCAASELYNKTRKKYQFIGEGTEFSSQELTHYLKKLSNKYPIISIEDGQDESDWEGFLYQTKELGNSLQLVGDDLFVTNKNILKKGIKKGVANAILIKLNQIGTLTETIETIKIAKKFNYGVIISHRSGETEDTSIADLSVGTASGQIKTGSMSRSDRTSKYNQLIRIEEILNKKRAPFYGLKEVKSSF
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: PDRP_STAAT
Sequence: MEKIKIIVASDSIGETAELVARAGISQFNPKQCKNELLRYPYIESFEDVDEVIQVAKDTNAIIVYTLIKPEMKQYMSEKVAEFQLKSVDIMGPLMDLLSASVEEKPYNEPGIVHRLDDAYFKKIDAIEFAVKYDDGKDPKGLPKADIVLLGISRTSKTPLSQYLAHKSYKVMNVPIVPEVTPPDGLYDINPKKCIALKISEEKLNRIRKERLKQLGLGDTARYATEARIQEELNYFEEIVSEIGCPVIDVSQKAIEETANDIIHYIEQNKSK
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.