PharMolix/UniProtQA huggingface dataset:
Protein: PP4R2_XENTR
Sequence: MDVDRLQEALKDFEKRGKKEASSELDQFLCHVAKTGETVVQWPQFKEYFVFKLEKVMDDFRSSAPDQRGSPNPNVEYIPFDEMKQRILKIVTGFNGTPFTIQRLCELLTDPRRNYTGTDKFLRGVEKNVMVVSCVYPSSEKNSSTSLNRMNGVMFPSNSQSYTDRSNVNGPGTPRPVNRPKFSLSSPMTTNGLPDSMENNESDLQQKEKSQSDSVASEDESQATTPKNKHSAEDSAETEEHEVKRLKFDTEEEEAACANPDASSEVSTEMAEEAESASASADKDKESCQSAQAADEESLMTPSESTEADSGERDSETVSVTEESSEESHQMEESEQSETACSLNSEEQNSAAAAASTVGTDTSEEEHLGTFGVKSTETLTLSPMENSEEATDAPEEPMDQD
What is the function of this protein?
Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4).
What are the official names of this protein?
Serine/threonine-protein phosphatase 4 regulatory subunit 2.
What is the protein family that this protein belongs to?
Belongs to the PPP4R2 family.
Protein: GATA3_XENLA
Sequence: MEVSAEQPRWVSHPHHPALLNGQHTDSHHQVHNYMDPSQYPPPEDMDVLFNIDAQGNHVPSYYSNSVRTVPRYPPPHHGSLVCHPSILQSWTDGRKSLGGPHAASAWNLPFTKPSIHHNSPGGLSVYPPASSASLATGHSSPHLFTFPPTPPKDVSPDPSISTSGSTSSSRHEEKECVVSKYQVSLGDTGMKLESLHPRNSMSGIGGVSAHHPITTYPDYYGAGLFQPGSILDGSPTHFSSNARPKTRSSTEGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRNRKMSSKSKKSKKFHDSLEDYPKSSSFSPAALSRHMSSLSHIPFSHSSHMLTTPTPMHPPSSLSFGPHHPSSMVTAMG
What are the official names of this protein?
GATA-binding factor 3, Transcription factor xGATA-3.
What are the subcellular locations of this protein?
Nucleus.
Protein: 5MP2B_DANRE
Sequence: MSYQKQQKPTLTGQRFKTRKRDEKERFDPSQFQESIVQGLNQTGTDLEAVAKFLDSSGAKLDYRRYAETLFDILVAGGMLAPGGALSDDMTRTKYCVFTAQEDIKTMKAYAQVFNKLIRRYKYLEKGFEEEIKKLLLFLKGFSESERNKLAMLTGVLLGNGSLSAAILSSLFNDNLVKEGVSPAFAVKLFKSWISEKDINSVAGSLRKVSMDNRLMELFPVNKRSYEHFSRYFTGAGLKEISDFARNQQSLGARKELQKELQEQISLGVSFKEIIDYCKEEMKRSSISEQLMIGIMWTSLMSDMEWNKKEELVTEQAIKHLKQHSPLLKAFSTQAQSELSLLQRIQEFCYDNIHFMKTFQKMVLLLYKVDVLSEEAVLKWFTEAHLAKGKSVFLEQMKTFVEWLKNAEEESESEEESD
What is the function of this protein?
Translation initiation regulator which may repress repeat-associated non-AUG (RAN) initiated translation probably by acting as a competitive inhibitor of eukaryotic translation initiation factor 5 (EIF5) function (By similarity).  Enhances histone H4 gene transcription but does not seem to bind DNA directly (By similarity).
What are the official names of this protein?
eIF5-mimic protein 2-B, Basic leucine zipper and W2 domain-containing protein 1-B.
What is the protein family that this protein belongs to?
Belongs to the BZW family.
Protein: PURA_DESAL
Sequence: MANIVVVGTQWGDEGKGKIVDMLAEKADMVTRFQGGNNAGHTVVVDGTQTITHLIPSGILQNKTCLIGNGVVVDPKVLLEEVDKLLGMGVEINADNLLISERAQIIMPYHQAMDHAREAKKGAQKIGTTGRGIGPCYEDKAARKGVRFVDLLDPAVFDSMVREACEEKNFLLTEFFKADPVDPDAIIAEYTEYAKRLAPHVVDVSVVLNQGVKDGKQVLFEGAQGTHLDIDHGTYPFVTSSNTVAGNVCAGSGVGPGQVNEVLGIVKAYTTRVGMGPFPTELEDEVGNRIQEKGAEFGATTGRRRRCGWLDMVLLEATARLNGLTGVAITKLDVLGGLDSLNICTAYECEGETLNFFPADLKVLAKCKPVYETMPGWTEDISGVRNFDDLPENARNYLNRVEELLGAPIKIISVGPGRDETMVVKDPFAG
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OCE8_LEPPU
Sequence: MAFLKKSLFLVLFLGLVSLSICDEEKRQDEDDDDDDDEEKRGVFDIIKGAGKQLIARAMGKIAEKVGLNKDGN
What is the function of this protein?
Has antibacterial activity against Gram-negative bacteria E. coli ATCC 25922 (MIC=60 uM), K. pneumoniae ATCC 700603 (MIC=240 uM) and S. choleraesuis ATCC 14028 (MIC=240 uM) and against Gram-positive bacterium S. aureus ATCC 29313 (MIC=240 uM).  Shows no hemolytic activity and no cytotoxicity.
What are the official names of this protein?
Ocellatin-PT8.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Ocellatin subfamily.
Protein: VNP_PSEPC
Sequence: GENEPPKKKAPDGCFGHKIDRIGSHSGLGCNKFKPGH
What is the function of this protein?
Increases urine flow and decreases blood pressure when administered to rats by intravenous injection.  Inhibits thrombin-induced platelet aggregation.  Stimulates cGMP production via the natriuretic peptide receptor-A (NPR1).
What are the official names of this protein?
Natriuretic peptide PNP.
What is the protein family that this protein belongs to?
Belongs to the natriuretic peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: ILVC_ECO24
Sequence: MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVGCGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLVVNLTPDKQHSDVVRTVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKLVEEGTDPAYAEKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADWANDDKKLLTWREETGKTAFETAPQYEGKIGEQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFSYACVPLLKPFMAELQPGDLGKAIPEGAVDNAQLRDVNEAIRSHAIEQVGKKLRGYMTDMKRIAVAG
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: FBX7_MOUSE
Sequence: MKLRVRLQKRTQPLEVPESEPTLGQLRAHLSQVLLPTLGFSSDTRFAITLNNKDALTGDEETLASYGIVSGDLICLVLEDDMPAPNLPSSTDTEHSSLQDNDQPSLAATPSQTNIPDEQGTDSSQGQATPFDAWTDDSMEGPSQNVEAESIQDAMSMEEVSGFHPLEPMLCNETEDGQVPHSLETLYQSAGCSNISDALIVLVHLLMLESGYIPQGTETKAVTMPEKWKSSGVYKLQYTHPLCEGGFAVLTCVPLGNLIIINATIKVNGGIKNVKSVQLQPGSYVAAGVEPGESAAKVYKDLKKLSRLFKDQLVYPLLAFTRQVLNLPDVFGLVVLPLELKLRIFRLLDVHSVLALSAVCHDLLIASNDPLLWRCLYLRDFRDGTVRGPDTDWKELYRKKHIQRKEAQRMRHAMFLPSAHPIPFCPIPVYPRAYLPTSLLPPGIIGGEYDERPILPSVGDPVTSLIPRPGELPGQFRPLRPRFDPVDPLPGPHSLLPGRAIPNNRFPFRPGRGRSADSRLPFL
What is the function of this protein?
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins and plays a role in several biological processes such as cell cycle, cell proliferation, or maintenance of chromosome stability.  Recognizes and ubiquitinates BIRC2 and the cell cycle regulator DLGAP5.  Plays a role downstream of PINK1 in the clearance of damaged mitochondria via selective autophagy (mitophagy) by targeting PRKN to dysfunctional depolarized mitochondria.  Promotes MFN1 ubiquitination.  Mediates the ubiquitination and proteasomal degradation of UXT isoform 2, thereby impairing the NF-kappa-B signaling pathway.  Inhibits NF-kappa-B pathway also by promoting the ubiquitinatioin of TRAF2 (By similarity).  Affects the assembly state and activity of the proteasome in the cells including neurons by ubiquitinating the proteasomal subunit PSMA2 via 'Lys-63'-linked polyubiquitin chains (PubMed:27497298).  Promotes 'Lys-48'-linked polyubiquitination SIRT7, leading to the hydrogen peroxide-induced cell death (By similarity).
What are the official names of this protein?
F-box only protein 7.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion. Cytoplasm, cytosol. Note=Predominantly cytoplasmic. A minor proportion is detected in the nucleus. Relocates from the cytosol to depolarized mitochondria (By similarity).
Protein: CHBG_YERPN
Sequence: MEKLLIVNADDFGLCKGQNYGIIDAFRNGVVSSTTAMMNSVDINHAAELSAQYPALPVGMHFVLTFGRPLTAMPSLTDANGELGKWLWQRAGAGTLDLNEIAQELECQFERFSAVFGRPPTHIDSHHHVHMLPQIYPLVAAFAREKSLPLRIDRHEVQQHGLTLDNPRSSEWFNAGFYGENLSEPSFLQLLEHADQQGVNSLEIMCHPAFIDQTLMTSGYCYPRLTELAILTSPTLKPAIAQRGYRLGSFLDC
What is the function of this protein?
Involved in the degradation of chitin.  ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose.  Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF.  Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P, the inducer of ChbR and the substrate of ChbF.
What are the official names of this protein?
Chitooligosaccharide deacetylase, COD, Chitin disaccharide deacetylase, Chitobiose deacetylase, Chitobiose-6P deacetylase, Chitotriose deacetylase, Chitotriose-6P deacetylase.
What is the protein family that this protein belongs to?
Belongs to the YdjC deacetylase family. ChbG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEND_PROMM
Sequence: MGLRHLVLCPGSRSGPLALAAGGMARTNRLRLSTAIDERSAAFLALGFSTATGTAAAVVTTSGTAVANLLPAAVEADRSCQPLLLLTADRPYRLKDCGANQTVNQETFLSPACRWIGQGPREGLHLFSKETLESFAEKAWQRAHHPAGAVHLNLPFEEPLHLSEEEQRMIWKGWSPKIPRSSPIKPINLAMAAEGTNGVTDQAPFALDPLRPGVVIAGAWRGLSKDLFAFQQSLREWQALSGWPVLADPLSALPSDQPGLIRSWELLLATGLLGSQEQLQVLRLGPMSASRSLEAWLKSFGDGQLLITEGDSRCLDPLGLSVQWNHGLTSWWQHHHHRWIDADAASQQATKALLRKWQISDRFAQEWLDQQLPLQGAITEPALARWLSRLLPTELPIMLAASSPVRDWLAYADKSLFSRRCFSFRGASGIDGTLSLSMGLAMALGPTLLVSGDLALLHDSNGWLLAHPQRPPLVVVLIDNGGGGIFEQLLVKTAPSEAFEQLFAMPQEVDPLALAGAHNIPHRQVACLEDLPAALEWGLFQAGPVLIRVCTHRRQDSSMRQQLREGLMMHLQSISQNGHIDL
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: CYB_CLECA
Sequence: MTIIRKKHPLIKIINHSFIDLPTPSNISSWWNFGSLLGLCLIIQILTGLFLAMHYTSDTSTAFSSVTHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGMYYGSYNMIETWNMGIVLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVFVHLLFLHETGSNNPTGLNSDADKIPFHPYYTIKDFLGVLILLMGLMILVLFFPDVLGDPDNYTPANPLNTPAHIKPEWYFLFAYAILRSIPNKLGGVLALILSILILALLPLLHTSKQRGLTFRPITQTMYWILVADLLILTWIGGQPVEYPFIIIGQMASIAYFAIIVILMPMAGMIENNILNLD
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GPMA_POLNS
Sequence: MKQLVLIRHGESAWNLENRFTGWADVDLTPKGAEQALAAGENLKKAGYEFDVAYTSVLRRAIRTLWNVQDTMDLMWLPVVHSWRLNERHYGALTGLNKAETAEKYGDEQVHIWRRSYDVRPPLLEHEDERHPKNDPRYSKLNSSDIPLGECLKDNVERVLPLWNESIAPALKAGKRVLLVAHGNSIRSLIKYLDQVSNEDIMEVNVPNGIPLVYELDDDLKPIQHFYLD
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: CYB6_ORYSA
Sequence: MSKVYDWFEERLEIQAIADDITSKYVPPHVNIFYCLGGITLTCFLVQVATGFAMTFYYRPTVTEAFSSVQYIMTEANFGWLIRSVHRWSASMMVLMMILHVFRVYLTGGFKKPRELTWVTGVVLAVLTASFGVTGYSLPWDQIGYWAVKIVTGVPDAIPVIGSPLVELLRGSASVGQSTLTRFYSLHTFVLPLLTAVFMLMHFLMIRKQGISGPL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: NPR3_PICGU
Sequence: MSFNIPNPSLLGIFLVISTHSGPTSVFSYPPELSSDKTSSQRRNRHEDNEDYNDQNNAPEEQKTNVKVDDEDDDGLSSEESDFSDEQFLLNEEWDSRNVNYYMGTKKDLLSFLDDEEKRRRSSGKERLRAPLSPELQPVISQENNSPSSNNLKKTVSEVSDSQQSSSSRNSGSNRKSSSAQTAKDNILGFDKEYLCELLCPPRSMCNSRFEITVDDHVFIGLPVHCYDNGSWRHKTKTKSTRSGSKVSADGQLYEDSQNSNSTSRATMSMFHLVFIMDPPVVEYNYRVDEMFHFVISRLALVLRYEQSKHDYVWKQVKLISKLKEDHRLSQGNDEGLHEFLVNRSSLCRSIKDCYEAISKHDIANLFVNKKLRSFQIPIKTEFHSLPEPTVPHLPGSYLSTTVNLLAGTGLINIGETTRYGMQGSLSSITPGSTYDADEDSLQTDSGSKTDDIIYFSLLLLDDPNSIIRDINAEPQSAIARFIHSIKPTESLERLAHKLNHHEKMESNIAEVKSFAFHLVYWRRARVIQPLSSRSVYIVSPMAPLSFNLYNDIKAFKAAFSSLPSLPHFLKLLSASSRKPKQFAAAIPSKDHRDIYMEALGWLMKYGYVTQLHTFVWLKISKKIKMKVEEDIEKESAGRKRSNPVTPSVEKYHKLLATDNTSKAYSDGPSDANIRRTRANKPSSSPSSGIGVNSNPYNTDIVLEKDGDTIILDPGRASSLERKWINKIIFDECKLTPAMVSVFYKFLKYMNGKNSLELLLLKENVSRHDLRKLMFAIEDHIISVRHW
What is the function of this protein?
Mediates inactivation of the TORC1 complex in response to amino acid starvation.  Required for meiotic nuclear division (By similarity).
What are the official names of this protein?
Nitrogen permease regulator 3, Required for meiotic nuclear division protein 11.
What is the protein family that this protein belongs to?
Belongs to the NPR3 family.
Protein: YQ53_SCHPO
Sequence: MKSTFSTVLITGSSKGLGYALVKVGLAQGYNVIACSRAPDTITIEHSKLLKLKLDVTDVKSVETAFKDAKRRFGNVDIVINNAGYGLVGEFESYNIEEMHRQMNVNFWGVAYITKEALNLMRESGKGGRILQISSVAGYYPSPCLSMYNASKFAVEGLSQTIMRELDPNWNIAITIVQPGGMQTEWASSNMQWAKPHPAYENDRSWRPFWENYHGCEETDPNKAAELLYSIAKLDRPPQKLVLGHDSLELIRKQHQDIGEELESNVALSTSVAKDDFDPASVETLRQNLQSM
What are the official names of this protein?
Uncharacterized oxidoreductase C162.03.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: DNAK_MYCS5
Sequence: MAKEIVLGIDLGTTNSVVSIVEGKNPTVLENPNGKRTTPSVVAFKNGEIIVGDAAKRQVETNPDTIISIKRLMGTNKTVKANNKEYKPEEISAMILSYMKDYAEKKLGQKVSKAVITVPAYFDNAEREATKNAGRIAGLEVLRIINEPTAAALAFGLDKNKAMKVLVYDLGGGTFDVSVLDLEDGTFEVLSTSGDNHLGGDDWDNEIVKWLTKEIKTKYSYDVSKDKYALARLKENAEKAKIDLSNQSVVQINIPFLAMSANGPINVELSLKRSEFEAMTSHLLDRTRKPIEDALKEAKLSANDIHEVLLVGGSTRMPAVQDMVKRTLGKEPNRSINPDEVVSIGAAIQGGVLAGHIDDILLLDVTPLTLGIETLGGVATPLIPRNTTIPATKSQVFSTAADNQTEVTISVIQGERQMASDNKMLGRFNLTGIEAAPRGVPQIEVTFSIDVNGITKVSAKDMKTQKEQTITIENSSKLSEEEIQKFIKDAEANKEADAKRKEEAETIVRAESLIDQVKKALEAQGDKADAKTKEESDKLIKELQDLIDKKDIPTLKAKLEEVENMMKNFANFAQQANATKDQSSKDQEEVATVVEE
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: ACKA_LIMF3
Sequence: MSKTIAVNAGSSTVKFKLFDMPSEEVVAEGNIERIGMDMGHAKIKYGDGQVSEEEKPFPNHGTAVSYLLDQLINLGIVKEYHEITAVGHRIVAGGEFFKDSVVIDDDVMQKIDELAEYAPLHNPAELQGIKAFKRVLPDAFAVAVFDTSFHSNMPEMNALYSVPYEWYEKYGARKYGAHGTSHRYVASRAAEMLGKPLEDLKLITCHIGAGASITAIKNGKSFDTSMGFSPLAGVTMATRSGDVDPSLVAFVQSKLGISSEEMIELLNHKSGLLGLSELSADMRDVQAAAEHGNKQCELALEIYENRVLKYIGSYLAELGGADAIVFTAGVGENDKEFRQAIGDKLAYFGVKVDPEKNDVRGEERDVSADDAKIKVLLIPTNEELMIVHDIERLRKQA
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARNT_SALDC
Sequence: MMKSIRYYLAFAAFIALYYVIPVNSRLLWQPDETRYAEISREMLASGDWIVPHFLGLRYFEKPIAGYWINSLGQWLFGATNFGVRAGAILTTLLAAALVAWLTFRLWRDKRTALLASVIFLSLFAVYSIGTYAVLDPMIALWLTAGMCCFWQGMQATTRTGKIGMFLLLGATCGLGVLTKGFLALAVPVVSVLPWVIVQKRWKDFLLYGWLAVLSCFVVVLPWAIAIARREADFWHYFFWVEHIQRFAMSDAQHKAPFWYYLPVLLAGSLPWLGLLPGALKLGWRERNGAFYLLGWTIMPLLFFSIAKGKLPTYVLSCFAPIAILMARFVLHNVKEGVAALRVNGGINLVFGIIGIVAAFVVSSWGPLKSPVWTHIETYKVFCVWGVFTVWAFVGWYSLCHSQQYLLPAFCPLGLALLFGFSIPDRVMESKQPQFFVEMTQAPLASSRYILADNVGVAAGLAWSLKRDDIMLYGHAGELRYGLSYPDVQDKFVKADDFNAWLNQHRQEGIITLVLSIAKDEDISALSLPPADNVDYQGRLVLIQYRPK
What is the function of this protein?
Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase, 4-amino-4-deoxy-L-arabinose lipid A transferase, Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase, Undecaprenyl phosphate-alpha-L-Ara4N transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 83 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YH219_YEAST
Sequence: MMPAKLQLDVLRTLQSSARHGTQTLKNSNFLERFHKDRIVFCLPFFPALFFVPVQKVLQHLCLRFTQVAPYFIIQLFDLPSRHAENLAPLLASCRIQYTNCFSSSSNGQVPSIISLYLRVDLSPFYAKKFQIPYRVPMIWLDVFQVFFVFLVISQHSLHS
What are the official names of this protein?
Putative UPF0479 protein YHR219C-A.
What is the protein family that this protein belongs to?
Belongs to the UPF0479 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: E313_ADECG
Sequence: MAMTEESVDQVEVNCLCVQHGQSCNNTRCFVKEGLRANWFYNPVLEEFAIPDSYQEGHGVNVKITFSHRSRNLRHNGHDVICSYSHLGSHISIRCTCNKPRPHLSLIEAACSMYNLD
What are the official names of this protein?
Early E3 13.3 kDa protein.
Protein: QKI_MOUSE
Sequence: MVGEMETKEKPKPTPDYLMQLMNDKKLMSSLPNFCGIFNHLERLLDEEISRVRKDMYNDTLNGSTEKRSAELPDAVGPIVQLQEKLYVPVKEYPDFNFVGRILGPRGLTAKQLEAETGCKIMVRGKGSMRDKKKEEQNRGKPNWEHLNEDLHVLITVEDAQNRAEIKLKRAVEEVKKLLVPAAEGEDSLKKMQLMELAILNGTYRDANIKSPALAFSLAATAQAAPRIITGPAPVLPPAALRTPTPAGPTIMPLIRQIQTAVMPNGTPHPTAAIVPPGPEAGLIYTPYEYPYTLAPATSILEYPIEPSGVLGAVATKVRRHDMRVHPYQRIVTADRAATGN
What is the function of this protein?
Isoform 4 acts as a translational repressor for GLI1.
What are the official names of this protein?
KH domain-containing RNA-binding protein QKI, Protein quaking, MqkI.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. SUBCELLULAR LOCATION: [Isoform 1]: Cytoplasm. Nucleus. Note=Isoform 1 localizes predominantly in the nucleus and at lower levels in cytoplasm. It shuttles between the cytoplasm and the nucleus. SUBCELLULAR LOCATION: [Isoform 3]: Cytoplasm. Nucleus. Note=Isoform 3 localizes predominantly in the cytoplasm and at much lower levels in nucleus. SUBCELLULAR LOCATION: [Isoform 4]: Cytoplasm. Nucleus. Note=Isoform 4 localizes both in the cytoplasm and nucleus.
Protein: TRMD_EXISA
Sequence: MKIDVLTLFPEMFHALDHSIVGRAKTLGQVEMSFLNFRDFSTNKHHKVDDYPYGGGAGMLLTPQPIFDAFHSLEAKSPRVILTTPTGKPFNQRMAEVWAKEEHLVFLCGHYEGFDQRIHDELATDEVSIGDFVLTGGELATMVMIDATVRLIPDVLNAQASHEDDSFSTGLLEYPHYTRPADFRGLTVPDVLLSGNHARIEAWRREQSLERTYRRRPDLLEHVELTDVDKKFLQSLRD
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPB_METLZ
Sequence: MKEKTGYYGEFGGRFVPETLMAALYELDSAYHRLKDDPGFKAELNSYLTEFAGRETPLTFCRNMSEYCGCKVYLKREDLVHGGAHKLNNTLGQALLAKAMGKKRLIAETGAGQHGVATAIAGAALNLPVEVFMGEEDCERQKLNVFRMELMGAKVHPVSSGTKTLKDATNEALREWAKTVDYTHYLIGSVVGPHPFPMIVRDFQSVIGEETRRQCLEKEGRLPDTLVACVGGGSNAIGMFYPMLNDDVRMVGVEAGGRALTPGNNGATLNTGSPGILHGALSYLIQNDDGQVGVTHSISAGLDYPGVGPEHSMLKDLNRVEYSYVMDDEVLEAFSYLSRTEGIIPALESAHAVSYVLKNRDSFDRDDIVVICLSGRGDKDVSSVSKMFGGEE
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: YIZC_BACSU
Sequence: MRNELFQQAKSFVQQAVMVTNGFEEGDQEQAILRAKNAVSSAYANSTDAERQQLHQFQNQLDKLQ
What are the official names of this protein?
Uncharacterized protein YizC.
Protein: NSRR_YERPS
Sequence: MQLTSFTDYGLRALIYMASLPDGQMTSISQVTEVYGVSRNHMVKIINQLSRVGLVTAVRGKNGGIRLGKPADQILIGDVVRQMEPLTLVNCSSDFCHITPACRLKQVLNQAVQSFLKELDNYTLADMVKDNSPLYKLLLVE
What is the function of this protein?
Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress.  May require iron for activity.
What are the official names of this protein?
HTH-type transcriptional repressor NsrR.
Protein: IFY1_CAEEL
Sequence: MEDLNFEERGSTQIPASLQQHFSAKLGRQNELEKTPSRGGLGLVVNSSKTPGGKSLQSLASACKVPPSTKKNTIPIAFECYEDETDDQIADVATIKKTEKHPCSPIDTANRCETFDSLAADIEDDMLNLEDQDVVLSEDRPYGDVIDPAESEAEALAELGVEEWDSYPPIDPASRIGDDFNYVLRTEDFAEEGDVKLEETRHRTVIADIDEVKMSKAERNELFSMLADDLDSYDLLAEEANLPL
What is the function of this protein?
Acts as a chaperone and as an inhibitor for separase sep-1 (PubMed:27249343, PubMed:28263324).  Plays an essential role in maintaining chromosome cohesion prior to meiotic and mitotic anaphase, in cytokinesis and in organizing the spindle and the centrosome (PubMed:12498686).  Ubiquitination-dependent degradation at the onset of anaphase is likely to activate sep-1 resulting in the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes (PubMed:12498686, PubMed:23578927).  Also required for cortical granule exocytosis (PubMed:17913784).
What are the official names of this protein?
Securin-like protein, Interactor of Fizzy protein.
What are the subcellular locations of this protein?
Cytoplasm. Chromosome. Cytoplasm, cytoskeleton, spindle. Note=Localizes to cytoplasm in germ cells. After oocyte nuclear envelope breakdown, localizes to chromosomes and spindle microtubules until meiotic anaphase I where the chromosome localization disappears. Maintained at low levels in the cytoplasm during meiosis II and in subsequent mitotic divisions during early embryogenesis. Localizes to chromosomes during mitotic metaphase at the 4E embryonic stage.
Protein: ARAA_THEMA
Sequence: MIDLKQYEFWFLVGSQYLYGLETLKKVEQQASKIVDSLNDDPIFPSKIVLKPVLKSSSEITEIFEKANADPKCAGVIVWMHTFSPSKMWIRGLSINKKPLLHLHTQYNREIPWDTIDMDYMNLNQSAHGDREHGFIHARMRLPRKVVVGHWEEKEVREKIAKWMRVACAIQDGRMGQIVRFGDNMREVASTEGDKVEAQIKLGWSINTWGVGELAERVKAVPEREVEELLKEYREKYIMPEDEYSLKAIREQAKIEIALREFLKEKNAVGFTTTFEDLHDLPQLPGLAVQRLMEEGYGFGAEGDWKAAGLVRAIKVMGTSLPGGTSFMEDYTYHLTPGNELVLGAHMLEVCPTIAKEKPRIEVHPLSIGGKADPARLVFDGQEGPAVNASIVDMGNRFRLVVNKVLSVPIERKMPKLPTARVLWKPLPDFKRATTAWILAGGSHHTAFSTAIDVEYLIDWAEALEIEYVVIDENLDLEDFKKELRWNELYWGLLKR
What is the function of this protein?
Catalyzes the conversion of L-arabinose to L-ribulose.
What are the official names of this protein?
L-arabinose isomerase.
What is the protein family that this protein belongs to?
Belongs to the arabinose isomerase family.