PharMolix/UniProtQA huggingface dataset:
Protein: AIL7_ARATH
Sequence: MAPPMTNCLTFSLSPMEMLKSTDQSHFSSSYDDSSTPYLIDNFYAFKEEAEIEAAAASMADSTTLSTFFDHSQTQIPKLEDFLGDSFVRYSDNQTETQDSSSLTPFYDPRHRTVAEGVTGFFSDHHQPDFKTINSGPEIFDDSTTSNIGGTHLSSHVVESSTTAKLGFNGDCTTTGGVLSLGVNNTSDQPLSCNNGERGGNSNKKKTVSKKETSDDSKKKIVETLGQRTSIYRGVTRHRWTGRYEAHLWDNSCRREGQARKGRQVYLGGYDKEDRAARAYDLAALKYWGSTATTNFPVSSYSKELEEMNHMTKQEFIASLRRKSSGFSRGASIYRGVTRHHQQGRWQARIGRVAGNKDLYLGTFATEEEAAEAYDIAAIKFRGINAVTNFEMNRYDIEAVMNSSLPVGGAAAKRHKLKLALESPSSSSSDHNLQQQQLLPSSSPSDQNPNSIPCGIPFEPSVLYYHQNFFQHYPLVSDSTIQAPMNQAEFFLWPNQSY
What is the function of this protein?
Probably acts as a transcriptional activator.  Binds to the GCC-box pathogenesis-related promoter element.  May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways.
What are the official names of this protein?
AP2-like ethylene-responsive transcription factor AIL7, Protein AINTEGUMENTA-LIKE 7, Protein PLETHORA 7.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. AP2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: COAE_BRUME
Sequence: MIVLGLTGSIGMGKTTAAGMFAEAGVPVYSADDAVHRLYSGRAAPLIEATFPGTVENGIVNREKLFKAVIGQPEAIKKLEAVVHPLVREEEDAFRREAEKSGAAIALVDIPLLFETGAEKRVDKVVVVSAPADIQHTRVLARPGMTQEKLKAILVRQIPDAEKRSRADFVLDTSGSFDDLRRQIAEIITGLSGKPAAATR
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDH_LARHH
Sequence: MNAPVRVAVTGAAGQIGYSLLFRIASGEMLGQNQPVILQLLDLPQAQNAVKGVMMELEDCAFPLLAGMVATDDPNVAFKDADICLLVGARPRSKGMERADLLEANGAIFTVQGKAIAENAKEDVKVLVVGNPANTNAYIARKAAEKVGRTNPANYTAMLRLDHNRALSQLAAKTGKAVASIENMAVWGNHSPTMYADYRFATVNGESVKSMINDEAWNRDVFLPTVGKRGAAIIEARGLSSAASAANAAIDHIRDWVLGTNGKWVTMGIPSDGSYGIPEGVTYGFPVTCKDGKYEIVQGLEIDEFSRACMNKTLAELEEERQGVAHLLG
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: RL3_CHLMU
Sequence: MRSQLSLIGKKEGMMHVFDKNGNLVACSVISIEPNVVAQLKTASSDGYNAVQMGADAVKAPEKTIEKRFSKALLGHFKKSGGCAFRVLKEVVVSEEAVQSVSLGDEFGVEIFDGVSNVDVCGISKGKGFQGVMKKFGFRGGPKSHGSGFHRHAGSIGMRSTPGRCFPGSKRPSHMGCDRVTVKNLEVVKVDLDRKVMLVKGAIPGFKGSVVVVKRSCGVEG
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: SYH_NOSS1
Sequence: MAKNDKINFSTPSGFPEFLPSEKRLELYLLDTIRRVYESYGFTPIETPAVERLEVLQAKGNQGDNIIYGLEPILPPNRQAEKDKSGDTGSEARALKFDQTVPLAAYIARHLNDLTFPFARYQMDVVFRGERAKDGRFRQFRQCDIDVVGREKLSLLYDAQMPAIITEIFEAVNIGDFVIRINNRKVLTGFFQSLNISETQIKSCISIIDNLEKIGEAKVKLELEKEGINPEQTQKIIDFVKIDGSVDDVLDKLKHLSQTLPESEQFNLGVSELETVITGVRNLGVPDKRFCIDLAIARGLNYYTGTVYETTLIGHEALGSICSGGRYEELVGTFIGEKMPGVGISIGLTRLISRLLKAGILNTLPPTPAQVVVVNMQDELMPTYLKVSQQLRQAGLNVITNFEKRQLGKQFQAADKQGIRFCVIIGADEAAAQKSSLKDLQSGEQVEVALADLAEEIKRRLT
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE1_BRUME
Sequence: MSKPVITRFAPSPTGYLHIGGARTALFNWLYAKHCGGKMLLRIEDTDRERSTEAATAAILDGLTWLGLDWDGEAISQFERAPRHREVAEELVANGKAYYCYASPEELEEMREKARAEGRPPRYDGRWRDRDPSEAPAGVKPVIRIKAPRDGETVVHDAVQGDVRFPNKDLDDFIILRSDGTPTYMHAVVVDDHDMGVTHIIRGDDHLTNAARQTIIYNAMGWDVPQMSHIPLIHGADGAKLSKRHGALGVDAYRAIGYLPAALRNYLVRLGWSHGDDEIMSTEQMIEWFDVKDINKGAARFDFQKLEAINGLYMRSSDDQALFDALVAVLPEIEGGKELAEALDDKGRAQLLLAMPGLKERAKTLVELADGAKFIFASRPLALDEKAASLLNDEGRAVLKPVYPVLEAMGEWTAESLDAAIRAHAEAEGLKLGKIAQPLRAALTGRATSPGVFDVLVVLGREESLARIGDQIG
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 1, Glutamyl-tRNA synthetase 1, GluRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTD_LACLS
Sequence: MKIVIQRVKSASVSIDGKIKEKINQGFLLFVGVEDADSNFDLDYAVRKIAQMRIFSDEADKMNLSVQDIQGEILSISQFTLYAETKKGNRPSFSAAGKPYFAKAMYEKFNDSLAQIVPVKAGVFGADMQVELINDGPVTIILDTKEARKNA
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IMM6_ECOLX
Sequence: MGLKLHINWFDKRTEEFKGGEYSKDFGDDGSVIERLGMPFKDNINNGWFDVIAEWVPLLQPYFNHQIDISDNEYFVSFDYRDGDW
What is the function of this protein?
This protein inhibits the 16S RNA hydrolyzing activity of colicin E6 by binding with high affinity to the C-terminal catalytic domain of E6.  This protein is able to protect a cell, which harbors the plasmid ColE6 against colicin E6.
What are the official names of this protein?
Colicin-E6 immunity protein, ImmE6, Microcin-E6 immunity protein.
What is the protein family that this protein belongs to?
Belongs to the cloacin immunity protein family.
Protein: SSRP_TOLAT
Sequence: MSKNKTKKGGDSTIALNKKARHDYFIEDKYEAGLALQGWEVKSLRAGKAHIGDSYVLLQNGEAFLFGATITPLNVASTHVVCDPTRIRKLLLKKSELERLIGLVERQSYTLIPLSMYWSRAWVKVEIGLAKGKKEHDKREDLKEREWQRDKERMMKNKGR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: TREA_RALSO
Sequence: MLDPRGLARPSRFCPRIIYAGTSHIRRATAAALLAASLCALPACADVGVGAALPLSPDKLYGELFVAVQTAQVYPDQKTFVDTVPKADPAVILQAYRAQKDVPGFSLKAFVDQYFTVPFETVITPPAGQSLRAHINWLWPALTRTTATAPDNSSLIPLPKPYVVPGGRFREVYYWDTYFTMLGLQASGRDDLVDSMLDNFAYQINRFGHIPNGNRTYYLSRSQPPFFALMVELAATKEGEAAYTRYLAPLRKEYAYWMRGAAGTAPGQASGNVVVLPDGTVLNRYWDDEATPRPESYLQDVATAQQAPDRPAAEVWRDLRAAAESGWDFSSRWFGDSATLATIRTTSILPVDLNALMFQLEKTIAKGCAVARDFACTVEFGNHARKRAVAVERYLWHPAGYYADYDWKLGKVRDNLSAAATYPLFVQMAPWGRARQTLRQTQTALLQVGGLSTTTLHTQQQWDAPNGWAPLQWIALQASQHYGQALLAQTIGERFLGSVERLYAAEQKLVEKYIVDGSGTGGGGGEYPLQDGFGWTNGVTLRLLDAYGRGQ
What is the function of this protein?
Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system.
What are the official names of this protein?
Periplasmic trehalase, Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 37 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: CIRD_CHAPA
Sequence: KIPCGESCVWIPCVTSIFNCKCENKVCYHD
What is the function of this protein?
Probably participates in a plant defense mechanism.  Inhibits the cytopathic effects of the human immunodeficiency virus.
What are the official names of this protein?
Circulin-D, CIRD.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Bracelet subfamily.
Protein: SUCC_ACIBC
Sequence: MNLHEYQAKALLKEYGMPVQEGILATNADEAVAAFEQLGGKFAVMKAQVHAGGRGKAGGVKVAKSKEDVIEFANNIIGTRLVTYQTDANGQPVNSIIVAEDVYPVERELYLGAVVDRSSRRITFMASTEGGVEIEKVAEETPEKIIKVEVDPLVGLQPFQAREVAFALGLKDKQIGQFVKIMTAAYQAFVENDFALFEINPLSVRENGEILCVDAKVGIDSNALYRLPKVAALRDKSQENERELKASEFDLNYVALEGNIGCMVNGAGLAMATMDIIKLYGGQPANFLDVGGGATKERVIEAFKIILADTSVQGVLINIFGGIVRCDMIAEAIIAAVQEVNVTVPVVVRLEGNNAELGAKLLDESGLKLISANGLSDAAEKVVAAVKA
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: U147A_HCMVM
Sequence: MSLFYRAVALGTLSALVWYSTSILAEINENSCSSSSVDHEDCEEPDEIVREEQDYRALLAFSLVICGTLLVTCVI
What are the official names of this protein?
Uncharacterized protein UL147A.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: ERBB_ALV
Sequence: MKCAHFIDGPHCVKACPAGVLGENDTLVWKYADANAVCQLCHPNCTRGCKGPGLEGCPNGSKTPSIAAGVVGGLLCLVVVGLGIGLYLRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQAHLRILKETEFKKVKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPYGCLLDYIREHKDNIGSQYLLNWCVQIAKGMNYLEERRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGADEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSVLEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIAEFSKMARDPPRYLVIQGDERMHLPSPTDSKFYRTLMEEEDMEDIVDADEYLVPHQGFFNSPSTSRTPLLSSLSATSNNSATNCIDRNGQGHPVREDSFVQRYSSDPTGNFLEESIDDGFLPAPEYVNQLMPKKPSTAMVQNQIYNNISLTAISKLPMDSRYQNSHSTAVDNPEYLNTNQSPLAKTVFESSPYWIQSGNHQINLDNPDYQQDFLPNETKPNGLLKVPAAENPEYLRVAAPKSEYIEASA
What are the official names of this protein?
Tyrosine-protein kinase transforming protein erbB.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
Protein: BIMM_BPT4
Sequence: METLVAGSIFMVLVSGVLAIIIYMLPWFIALMRGSKSTVGIFFASLLFNWSIIGWFITFIWSIAGETKKSAQPNQVIIIREKE
What is the function of this protein?
Inhibits of the DNA ejection of T4 into the host cytoplasm.  By this means, T4 excludes superinfection by the phages of the same family.
What are the official names of this protein?
Immunity protein.
What are the subcellular locations of this protein?
Host cell inner membrane; Multi-pass membrane protein.
Protein: RS2_BURP0
Sequence: MAITMRQMLEAGVHFGHQTRFWNPKMAPFIFGHRNKIHIINLEKTLPMYNDALKYVRQLAANRGTILFVGTKRQSRDTIAQEALRAGMPYVNARWLGGMLTNFKTLKVSIKRLKDMEAAVEAGELEKMSKKEALLFEREIAKLQKSIGGVKDMGGIPDAIFVVDVGYHKIAVTEANKLGVPVIAVVDTNHSPEGVDYVIPGNDDSSKAVALYAQGVADAILEGRANAVNEVVQAVRGDDEYVEENA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: MOAA_SULDN
Sequence: MLIDSYDRVVDYLRISVTERCNFRCQYCMPEKPFSWVPKENLLTFEELFLFVKVAIDEGIRKIRITGGEPLLREDLDKFIKMIFDYAPDIDLAMTTNAYLLKSTAQKLRDAGLKRLNVSIDTLKPEVAFAIAGKDVLKNVLDGVNEALAVGLKVKVNMVPMKNMNAQEIVDVLEYSKKRGMTIRFIEYMENKFASKEISGLKSDELLSMLREHYEFVDEGYDGASPSRYYKMSDGYRFGIIEPYGDDFCKQCNRIRLTAEGQLIPCLYFDEALSIAKSIKEGDIVAASEVLRDVVKNKPEKNRWGGEDGEVSTRAFYETGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: ILVC_SYNS9
Sequence: MAQLFYDSDADLGLLNGKTVAIIGYGSQGHAHALNLKDSGVNVVVGLYEGSRSAEKAKADGLEVLTVAEASAKADWIMVLLPDEFQKDVYEKEIAPHLKSGKVLSFAHGFNIRFELIKPPADVDVVMIAPKGPGHTVRWEYQNGQGVPALFAIEQDASGNARGLTMAYAKGIGGTRAGILETNFKEETETDLFGEQAVLCGGLSELVKAGFETLVEAGYQPELAYFECMHEVKLIVDLMVKGGLTSMRDSISNTAEYGDYVSGPRLITADTKAEMKRVLADIQDGTFARNFVAECDAGKPEMKKIRDRDAQHPIEKVGKGLRSMFSWLKDA
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: CAF17_ASPCL
Sequence: MRPTTSTQNICARCLNRGRHFSTNVQHRAQQPSNAIVSSPPQTGYARLTNRGLISITGIDSTTFLQGLITQNMLVANDPNRAIRRTGTYAAFLNSQGRVLNDAFIYPMPRVDGGAAAPEDPAWLVEVDKCEVSSLMKHLKKHKLRSKLKLRALEDGERTVWSSWKDHTEPRWAAYNLESESSSQFSPSSPIAGCVDTRAPGFGSRIVTPGGEDLRMHFPDEAQVAGGEVDLGAYTVRRMLHGIAEGQSEIIRESALPLECNMDMARGVDFRKGCYVGQELTIRTHHTGVVRKRIVPVQLYTGAQDTVPVDGLPAYDSSVEVPSPPSGTNISKVGARKGRSAGKFLGGVGNIGLALCRLEMMTDIVLTSEGTQYNPETEFKVSWTAADEGPVGPSDSGEVKIKAFVPPWLREYIASGGVRNTARKIDNEDAQRARELLYQLDEEEELRRNE
What are the official names of this protein?
Putative transferase caf17, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the GcvT family. CAF17 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: C_PI3H4
Sequence: MLKTIKSWILGKRNQEINQLISPRPSTSLNSYSAPTPKKTYRKTTQSTQEPSNSAPPSVNQKSNQQKQVKKLVDQLTKIDSLGHHTNVQQKQKIEILIRKLYREDLGEEAAQIVELRLWSLEESLEASQILKMEPKTRRILISMKLERWIRTLLRGKCDNLQMFQARYQEVMSYLQQNKVETVIMEEAWNLSVHLIQDQ
What are the official names of this protein?
Protein C, VP18 protein.
What is the protein family that this protein belongs to?
Belongs to the respirovirus protein C family.
Protein: TRHO_BACP2
Sequence: MEKQYRVLLYYQYVPIEDPETFTAEHLAFCKELGLLGRILISSEGINGTVSGTIEQTDKYMEALKEDPRFASMPIKIDEADGHAFKKMHVRHRNELVNLSLEDDVNPLELTGKHLSPVEFYEQMQSPDTVVIDARNDYEFDVGHFRGAVRPDIETFRELPEWIRDNKEILEGKKILTYCTGGVRCEKFSGWLKREGFEDVSQLDGGIVTYGKDPEVQGKLWDGQCYVFDTRLTVPVNQTEHVVVGKDFFTGEPCERYVNCANPACNRKMIATEESEHKYMRSCSHECRTSERNLYVKQHNLSEEEVQERLAVIEQEQAISQG
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: LIS1_CANAW
Sequence: MEKLQILTERQQTELNHAIIQYLQPLCQQDNHVLLDQLSKLLNIDQSTQESNNVEKVDNYLEKRWSTVLRLQKKIIDLENEISNLNNIINSTNSDNNGIILSKDKINWIPKGAVKQSYQCENIVTTVKLHPNLPLVLNGCNDGNLYIWNISNDDNTIPEKMIKAHTRAINKICFTYKKPYYLATCSSDLTIKIWDEKFNHIRTLNGHEHTVSSIQFSPVDNSILYSVSRDKNIRVWDIFQGISLKSFVGHSEWCRDLDIISSDTYGDFVLTCSNDQSARLSHANSGAGVAMIVGHSHVVETVKFLPSLQANKILDEYITKNTEQFPTIPLELLKDKTYNQLGFKYCITASRDNTIKLWLIPPPTIAPHRPPLPSKYNNSQSWLIAELKGHSSWVKSLCVHPNGKFIISGSDDKTIKFWDLSGLLETGYVNVVKTIIGHDGFINDIDFARLKEASDVSEEDLLKQVEKRMRCLFISGSADNSIKLWN
What is the function of this protein?
Positively regulates the activity of the minus-end directed microtubule motor protein dynein.  Plays a central role in positioning the mitotic spindle at the bud neck during cell division.  Targets cytoplasmic dynein to microtubule plus ends, thereby promoting dynein-mediated microtubule sliding along the bud cortex and consequently the movement of the mitotic spindle to the bud neck.
What are the official names of this protein?
Nuclear distribution protein PAC1, Lissencephaly-1 homolog, LIS-1, nudF homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LIS1/nudF family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes to the plus ends of microtubules and the mitotic spindle poles.
Protein: RAB12_RAT
Sequence: MDPSAALHRRPAGGGLGAVSPALSGGQARRRKQPPRPADFKLQVIIIGSRGVGKTSLMERFTDDTFCEACKSTVGVDFKIKTVELRGKKIRLQIWDTAGQERFNSITSAYYRSAKGIILVYDITKKETFDDLPKWMKMIDKYASEDAELLLVGNKLDCETDREISRQQGEKFAQQITGMRFCEASAKDNFNVDEIFLKLVDDILKKMPLDVLRSELSNSILSLQPEPEIPPELPPPRPHVRCC
What is the function of this protein?
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes.  Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion.  That Rab may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor.  Involved in autophagy (By similarity).
What are the official names of this protein?
Ras-related protein Rab-12.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Recycling endosome membrane; Lipid-anchor; Cytoplasmic side. Lysosome membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane. Cytoplasmic vesicle, autophagosome.
Protein: IAA4_ARATH
Sequence: MEKVDVYDELVNLKATELRLGLPGTEETVSCGKSNKRVLPEATEKEIESTGKTETASPPKAQIVGWPPVRSYRKNNVQTKKSESEGQGNYVKVSMDGAPYLRKIDLTMYKQYPELMKSLENMFKFSVGEYFEREGYKGSDFVPTYEDKDGDWMLVGDVPWEMFVSSCKRLRIMKGSEVKGLGCGGL
What is the function of this protein?
Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations.  Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin-responsive promoter element (AuxRE).  Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression.
What are the official names of this protein?
Auxin-responsive protein IAA4, Auxin-induced protein AUX2-11, Indoleacetic acid-induced protein 4.
What is the protein family that this protein belongs to?
Belongs to the Aux/IAA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FTSZ_PSEPK
Sequence: MFELVDNVPQSPVIKVIGVGGGGGNAVNHMVKSSIEGVEFICANTDAQALKNIGARTILQLGTGVTKGLGAGANPEVGRQAALEDRERIAEVLQGTNMVFITTGMGGGTGTGAAPIIAEVAKEMGILTVAVVTRPFPFEGRKRMQIADEGIRMLAESVDSLITIPNEKLLTILGKDASLLSAFAKADDVLAGAVRGISDIIKRPGMINVDFADVRTVMGEMGMAMMGTGCASGPNRAREATEAAIRNPLLEDVNLQGARGILVNITAGPDLSLGEYSDVGSIIEAFASDHAMVKVGTVIDPDMRDELHVTVVATGLGARIEKPVKVVDNTLQTAQQAYEASNPAPVRQEQPAVNYRDLERPTVMRNQAHAGAAAAAKLNPQDDLDYLDIPAFLRRQAD
What is the function of this protein?
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site.  The regulation of the ring assembly controls the timing and the location of cell division.  One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells.  Binds GTP and shows GTPase activity.
What are the official names of this protein?
Cell division protein FtsZ.
What is the protein family that this protein belongs to?
Belongs to the FtsZ family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane.
Protein: LEPA_MYCMS
Sequence: MDKSKIRNFSIIAHIDHGKSTLADRILELTNTVEKREMQDQLLDSMDIERERGITIKLNSVQLKYHSKDNQDYIFNLIDTPGHVDFTYEVSRSLAACEGAILVVDASQGVEAQTLANVYLAIDSNLEIIPVINKIDLPSADVDKVKHEIEEIIGLDCSKSPLISAKTGLNVEDVLQAIVEKIPSPSDAIDNAPLKALIFDSYYDKYLGVVMSIRLKQGMLKVGDKIKLMSTNAEYEVTSLGIKTPKIVKKDFLEAGEVGWVAASIKTIKDVNVGDTITSVLNPADEPLDGYKKLKPMVYCGIYPIDTNKYQDFKEALEKIELSDSSLVYEPETSQALGFGFRCGFLGLLHMEVIQERLEREYNLELIATAPSVVYKVHLTNKQVIELDNPALLPEAQKISKIEEPFVEIKIATPSEYIGDLMNLCQNKLGIYKNMEVIDNNRRILIYQMPLAEIIFDFFNKLKSISKGYASFEYELIGYKESKLVRMDIKLNGEMVDAFSMIVNQKFAYQRGSALTLKLKELIPRQNFEVPVQATIGNKVISRETIKAYRKDVTWKLHAADKSRRKKLLEKQKEGKIKMKEIGTVEVPQEAFVAILKIDD
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL17_STRAW
Sequence: MPKPTKGARLGGSAAHEKLLLANLAKSLFEHGRITTTEAKARRLRPYAERLVTKAKKGDLHNRRQVLQVITDKSVVHTLFTEIGPRYENRPGGYTRITKIGNRRGDNAPMAVIELVEALTVAQQATGEAEAATKRSAKDAEAKTEAPAEVVEDTKPADEAAEESKDA
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: KDSB_RICRO
Sequence: MRHQDVAIIIPSRLSSTRLKQKPLQLIGSITLIERVFKQVNQAGLEHTYVATDSEEIASVITKVGGKVIFTDSAIPTGTDRTYEAFKLIPNNQNINYIVNVQGDMPFIEPSSILKIIEYLKNSKYDIVTPIVKVDRESVKASSNVTVVVDSAGTALYFSRSLIPNGAEEFLYHVGMYGFRKNALEKFVSLKPTFLEKTERLEQLRALENGMTIGTCLVENVPISVDTEEDLKKAVKFYENISKLGL
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROE_YERE8
Sequence: MDQKFAVFGNPIGHSKSPRIHALFAEQTGIEHCYGMVLAPNETFEETLTSFFAGGAIGANITTPFKERAHAKCDELTDRASLAGAVNTIKQLKDGRLLGDNTDGIGLLSDLERQHLIQTTDHILLVGAGGAARGVILPLLSYGCKVVITNRTYARAQQLAEVFHHLGDIDAVEMQDLSGQPFDLIINATASGIHGEVPNLPMDIISPQTRCYDMFYQADSTPFLAWSTRLGVTSYADGLGMLVGQAAHAFQLWHGVMPEITPVLNQLRDELAK
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.