PharMolix/UniProtQA huggingface dataset:
Protein: GLDH_ARATH
Sequence: MLRSLLLRRSVGHSLGTLSPSSSTIRSSFSPHRTLCTTGQTLTPPPPPPPRPPPPPPATASEAQFRKYAGYAALAIFSGVATYFSFPFPENAKHKKAQIFRYAPLPEDLHTVSNWSGTHEVQTRNFNQPENLADLEALVKESHEKKLRIRPVGSGLSPNGIGLSRSGMVNLALMDKVLEVDKEKKRVTVQAGIRVQQLVDAIKDYGLTLQNFASIREQQIGGIIQVGAHGTGARLPPIDEQVISMKLVTPAKGTIELSREKDPELFHLARCGLGGLGVVAEVTLQCVARHELVEHTYVSNLQEIKKNHKKLLSANKHVKYLYIPYTDTVVVVTCNPVSKWSGPPKDKPKYTTDEAVQHVRDLYRESIVKYRVQDSGKKSPDSSEPDIQELSFTELRDKLLALDPLNDVHVAKVNQAEAEFWKKSEGYRVGWSDEILGFDCGGQQWVSESCFPAGTLANPSMKDLEYIEELKKLIEKEAIPAPAPIEQRWTARSKSPISPAFSTSEDDIFSWVGIIMYLPTADPRQRKDITDEFFHYRHLTQKQLWDQFSAYEHWAKIEIPKDKEELEALQARIRKRFPVDAYNKARRELDPNRILSNNMVEKLFPVSTTA
What is the function of this protein?
Involved in the biosynthesis of ascorbate (PubMed:18190525).  Catalyzes the final step of ascorbate biosynthesis (PubMed:18190525).  Uses L-galactono-1,4-lactone and L-gulono-1,4-lactone as substrates, but not D-galactono-1,4-lactone, D-gulono-1,4-lactone, L-mannono-1,4-lactone or D-galactonic acid (PubMed:18190525).  Also active with phenazine methosulfate and 1,4-benzoquinone as electron acceptors (PubMed:18190525).  Involved in the regulation of the accumulation of the mitochondrial respiratory complex I (PubMed:18799460, PubMed:33060577).  Structural part of one of the plant-specific mitochondrial complex I assembly intermediates, lacking the whole distal (PD) module (PubMed:33060577).  Prevents the binding of the plant specific P1 protein (CPN60/HSP60), responsible for the linkage of the proximal (PP) to the distal (PD) module (PubMed:33060577).
What are the official names of this protein?
L-galactono-1,4-lactone dehydrogenase, mitochondrial.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: ARGJ1_STRCL
Sequence: MTVTAPKGSTGGGCRRGSKESGQPDLALVVNEGPRRAAAGVFTANRVKAAPVLWSQQVLRGGEVSAVVLNSGGANACTGPKGFQDTHATAERAAAALGHSAAEIAVASTGLIGTYLPMDRLLPGIDKAAAELSPHGGERAAIAIRTTDTVHKTAVRAGEGWSVGGMAKGAGMLAPGLATLLVVLTTDADLAPPVLDKAVRDAVRTTFERVDSDGCMSTNDTVLLLASGASGGDPGYEEFADVLREVCEDLARKLIGDAEGASKDIRIEVIHAATEDDAVEVGRTIARNNLLKCAIHGEDPNWGRVLSAIGTTKAVFEPERLNVAINGVWVCREGSAGDGRDLVDMRFREVRITADLDAGTHSAVIWANDLTAEYVHENSAYSS
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ 1.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUD_ALKCK
Sequence: MEPIQVHKGKAVVLDRVNIDTDQIIPKQFLKRVERTGFGQYLFYDWRFQADGADNPAFELNQPEANGASILITGHNFGCGSSREHAPWALYDYGFRVIIAPSFADIFYNNCVKNGLLPIRLSPEETELWMERAKESQEEITVDLGEQLIKQNGLETKFEMDSYWKQMLYNGWDEISLTLQYEEAIAKYEHRQSAVNK
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: YCF3_HELAN
Sequence: MSRSRINGNFIDKTFSIVANILLRIIPTTSGEKEAFTYYRDGMSAQSEGNYAEALQNYYEAMRLEIDPYDRSYILYNIGLIHTSNGEHTKALEYYFRALERNPFLPQAFNNMAVICHYRGEQAIRQGDSEIAEAWFDQAAEYWKQAIALTPGNYIEAHNWLKITRRFE
What is the function of this protein?
Essential for the assembly of the photosystem I (PSI) complex.  May act as a chaperone-like factor to guide the assembly of the PSI subunits.
What are the official names of this protein?
Photosystem I assembly protein Ycf3.
What is the protein family that this protein belongs to?
Belongs to the Ycf3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: H2B_DROHY
Sequence: MPPKTSGKAAKKAGKAQKNITKNDKKKKRKRKESYAIYIYKVLKQVHPDTGISSKAMSIMNSFVNDIFERIAAEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: ARGP_ENT38
Sequence: MKRPDYRTLQALDAVIRERGFERAAQKLCITQSAVSQRIKQLENMFGQPLLVRTVPPRPTEQGQKLLALLRQVELLEEEWLGDEQTGSTPLLLSLAVNADSLATWLLPALSAVLADSPIRLNLQVEDETRTQERLRRGEVVGAVSIQPQALPSCLVDQLGALDYLFVGSKAFADRYFPNGVTRAALLKAPAVAFDHLDDMHQAFLQQNFDLPPGSVPCHIVNSSEAFVQLARQGTTCCMIPHLQIEKELKSGELIDLTPGLYQRRMLYWHRFAPESRMMRNVTDALLAYGHKVLRQD
What is the function of this protein?
Controls the transcription of genes involved in arginine and lysine metabolism.
What are the official names of this protein?
HTH-type transcriptional regulator ArgP.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: PANB_PYRAR
Sequence: MPDKKRRVTDFVKGGGPYVWVTAYDYPTAKLVDEAGVDGILVGDSLGMVVLGLPNTLGVTLADMVRHTQAVARAAPKALVVADMPFMTYETGPRDALRNAARLIRAGAEAVKLEGGSEYAHVVEKLVKAGIPVMGHIGLNPQRVLALGGFKMVGKTEEQKKKLVEDAKALRDVGVFAIVVEFVPASVAKEVTQSVDVPTICIGAGPHCDGQILVLHDVVGLSERTPSFAKRYANVAEQILSAVRQYVQEVRTKAFPAKEHYRDV
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSRG_ECO57
Sequence: MHVTLVEINVHEDKVDEFIEVFRQNHLGSVQEEGNLRFDVLQDPEVNSRFYIYEAYKDEDAVAFHKTTPHYKTCVAKLESLMTGPRKKRLFNGLMP
What is the function of this protein?
Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle.  Catalyzes the conversion of (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5-phosphonooxypentane-2,4-dione (P-HPD).
What are the official names of this protein?
(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase, Autoinducer 2-degrading protein LsrG, AI-2-degrading protein LsrG, Phospho-(S)-4,5-dihydroxy-2,3-pentanedione isomerase, Phospho-AI-2 isomerase.
What is the protein family that this protein belongs to?
Belongs to the LsrG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ELF1_BOVIN
Sequence: MAAVVQQNDLVFEFASNVMEDEQQLGDPAIFPAVIVEHVPGADILNSYAGLACVEEPNDMITESSLDVAEEEIIDEDEDDITLTVEASCHNGDETIETIEAAEALLNMDSPGPMLDEKRMNNSIFSSSEDDMVVAPVTHVSVTLDGIPEVMETQHVQETYAHSPGPSSPEQPKRKKGRKTKPPRPDSPTTTPNISVKKKNKDGKGNTIYLWEFLLALLQDKATCPKYIKWTQREKGIFKLVDSKAVSRLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQFKDMPKDLIYIDDEDPSCSIESSDPSLSSTATSSRNPASRSRASSSPGIKGGATTVLKPGNSKAAKPKDPMEPVQPSEALRTVQSTQAPYPTQLFRTIHVVQPVQAVPEAEAASSMPEETLNPSVPSIRTIQTPAQVPVVVSPGNQHLHTVTLQTVPITTVIASADPSSAAGSQKFILQAIPSSQPMTVLKENVVLQSQKPGSPPSIVLSPAHVQQVLTSSVPTVCNGTVSAASAPSFSATTPMVTFSHHSSQLVAHPPGTVITSVIKAQEAKTHIQEEVKKEVEDNEKQGTEDAEQQLQPYVMVVSNGFPSQAAIKNELLEPSSF
What is the function of this protein?
Transcription factor that activates the LYN and BLK promoters.
What are the official names of this protein?
ETS-related transcription factor Elf-1, E74-like factor 1.
What is the protein family that this protein belongs to?
Belongs to the ETS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GSP_ECOLI
Sequence: MSKGTTSQDAPFGTLLGYAPGGVAIYSSDYSSLDPQEYEDDAVFRSYIDDEYMGHKWQCVEFARRFLFLNYGVVFTDVGMAWEIFSLRFLREVVNDNILPLQAFPNGSPRAPVAGALLIWDKGGEFKDTGHVAIITQLHGNKVRIAEQNVIHSPLPQGQQWTRELEMVVENGCYTLKDTFDDTTILGWMIQTEDTEYSLPQPEIAGELLKISGARLENKGQFDGKWLDEKDPLQNAYVQANGQVINQDPYHYYTITESAEQELIKATNELHLMYLHATDKVLKDDNLLALFDIPKILWPRLRLSWQRRRHHMITGRMDFCMDERGLKVYEYNADSASCHTEAGLILERWAEQGYKGNGFNPAEGLINELAGAWKHSRARPFVHIMQDKDIEENYHAQFMEQALHQAGFETRILRGLDELGWDAAGQLIDGEGRLVNCVWKTWAWETAFDQIREVSDREFAAVPIRTGHPQNEVRLIDVLLRPEVLVFEPLWTVIPGNKAILPILWSLFPHHRYLLDTDFTVNDELVKTGYAVKPIAGRCGSNIDLVSHHEEVLDKTSGKFAEQKNIYQQLWCLPKVDGKYIQVCTFTVGGNYGGTCLRGDESLVIKKESDIEPLIVVKK
What is the function of this protein?
Catalyzes the formation of an amide bond between glutathione (GSH) and spermidine coupled with hydrolysis of ATP; also catalyzes the opposing reaction, i. e.  the hydrolysis of glutathionylspermidine (Gsp) back to glutathione and spermidine.  The amidase active site can also hydrolyze Gsp-disulfide (Gsp-S-S-Gsp) to Gsp-SG and Gsp S-thiolated proteins (GspSSPs) to GSH S-thiolated protein (GSSPs).  Likely acts synergistically with glutaredoxin to regulate the redox environment of E. coli and defend against oxidative damage.  In vitro, the amidase active site also catalyzes hydrolysis of amide and ester derivatives of glutathione (e. g.  glutathione ethyl ester and glutathione amide) but lacks activity toward acetylspermidine (N1 and N8) and acetylspermine (N1).
What are the official names of this protein?
Bifunctional glutathionylspermidine synthetase/amidase, GspSA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the glutathionylspermidine synthase preATP-grasp family.
Protein: MXT_CAEEL
Sequence: MLHNYDDFGGGKMQGAPQVPRNTLLSVDQQLQLMNTINNMVRASQFTSQLANTIFTLCAQLKTSGSMLEQSHKNELNKVFTSLRQACCRDNGQLGTPCRLKIMELVELRAMNWRTNLAHSQYYVNRPEGQHDPAPTVGIPPSATSPPTQVTSSVTSPVPSSPQPPMQFVPQNPMMFQDPMAANHNAGGIFFIPAASTWMNPLMPMPPNPFLPHSMIPPDHQMFLRQRSLNKKPNNLMNKTLQLRHEMIIRNSDSGKIMGVKGRRVAAVEQLTNTVISFQKVDSKSKERTLTITASTMEDIERAKDMIIDTIRRNMSPMRTDMSIPPPNQYSGMSSENQSIPSQQNTANIDEDDDDDDEDIKLEQTSDGKLTFHCDDPELLAAAQEALSAYLRVRARPSAEEREKKKERRKSMPLQQTARDQQEPVMLKPAKTFHGSTPNLADGLAATTTVVVASIPQPMVPNVHASGDNPIRYNRDTLMTARDTKRAPIPDEMLQEINRVAPDILIA
What is the function of this protein?
Plays a role in promoting translation.
What are the official names of this protein?
Eukaryotic translation initiation factor 4E-binding protein Mextli homolog.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1434_THEAB
Sequence: MIITTTENIHGYEIVEILGIVMGNIVQSKHLGKDIAAAFKTLAGGEIKAYTEMMTEARNKAIERMIDEAEKIGADAVVNVRFSSSSVMSGAAEMLAYGTAVKIKKSNE
What are the official names of this protein?
UPF0145 protein THA_1434.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: PYRD_SHESH
Sequence: MFYKIAQKVMFQMDPEKAHHLAIASLKATANTPLDCFYAQKFTQAPVEFMGVTFPNPVGLAAGMDKDGECIDGFHAMGFGHIEVGTVTPRPQPGNDLPRLFRLKPAKAIINRMGFNNKGVDNLVANLKAAKSGALVGVNIGKNKDTPVEQGKDDYLICMEKVYEYSAYIAVNISSPNTPGLRSLQYGDLLDDLLGSLKAKQKDLAEKHGKYVPIALKIAPDLSSEEIEKIADSLIRNQFDGAIATNTTLSRDGVSGLMNSNEAGGLSGKPLNSLSTAVIKQLSDCLKGEIPIIGVGGINTASDALDKLDAGAQMVQIYSGFIYQGPKLIQDIVEAYRAR
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GLPK_BACCR
Sequence: MKKYILSLDQGTTSSRAILFNKKGEIVHSAQKEFTQHFPKPGWVEHNAQEIWGSILAVIATCLSEADVKPEQIAGIGITNQRETTVVWDKTTSKPIYNAIVWQSRQTAEICDELKEKGYSEMVREKTGLLIDAYFSGTKVKWILDNVEGAREKAENGDLLFGTIDSWLVWKLSGGKAHVTDYSNASRTLMFNIHDLQWDDELLEMLTVPKSMLPEVRPSSEIYGETIDYHFFGQNVPIAGVAGDQQAALFGQACFGEGMAKNTYGTGCFMLMNTGEKAVASEHGLLTTIAWGIDGKVNYALEGSIFVAGSAIQWLRDGMRMFKDASESEVYASRVESTDGVYVVPAFVGLGTPYWDSEVRGAMFGVTRGTTKEHFIRATLESLAYQTKDVLCAMEADSGIELKTLRVDGGAVKNNFLMKFQSDILDVPVERPVINETTALGAAYLAGLAVGYWKNQDEIKEQWHMDKRFEPTMEAKTSEELYAGWKKAIEATKAFK
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: LIGO3_MOUSE
Sequence: MTCWLHMLGLHLLLLPTAPLAAGCPARCECSASTRTVACGRRRLTAIPEGIPAETRMLELSRNRIRCLNPGDLASLPTLEELDLNHNVIAHVEPGAFANLPRLRVLRLRGNQLKLIPPGVFTHLDSLTLLDLSENKLVILLDFSFQDLRSLQRLEVGDNDLVFISRRAFAGLLGLAELTLERCNLTSLSPESLGHLRGLGALRLRHLAIAALEDQNFQKLPGLSHLEIDNWPLLEEVAPGSLRGLNLTSLSITHTNITAVPAAALRQQAHLTCLNLSHNPISMVPRGSFRDLVRLRELHLAGALLAVIEPQAFVGLRQIRLLNLSDNLLSTLEENTFHSVNTLETLRVDGNPLACDCRLLWIVQRRKTLNFDGRLPACATPAEVRGDALHNLPDSVLFEYFVCRKPKIRERRLQHVTATEGDDVRFLCRAEGEPAPTVAWVTPQHHSVTAASRGRARVLPGGTLTIADTRPQDSGTYTCVASNAGGNDTYFATLTVQPAANRTQGDGHNETQVGVRFPLDLTTILVSTAMGCITFLGVVLFCFLLLFVWSRGRGQHKNNFSVEYSFRKVDGPAAAAGQGGARKFNMKMI
What are the official names of this protein?
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 3, Leucine-rich repeat neuronal protein 6B.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: PCRB_STAA3
Sequence: MYDIKKWRHIFKLDPAKHISDDDLDAICMSQTDAIMIGGTDDVTEDNVIHLMSRVRRYPLPLVLEISNIESVMPGFDFYFVPTVLNSTDVVFHNGTLLEALKTYGHSIDFEEVIFEGYVVCNADSKMAKHTKANTDLTTEDLEAYAQMVNHMYRLPVMYIEYSGIYGDVSKVQAVSEHLTETQLFYGGGISSEQQATEMAAIADTIIVGDIIYKDIKKALKTVKIKESSK
What is the function of this protein?
Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP).  This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales.
What are the official names of this protein?
Heptaprenylglyceryl phosphate synthase, HepGP synthase, Glycerol-1-phosphate heptaprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GGGP/HepGP synthase family. Group I subfamily.
Protein: RUTD_ECOK1
Sequence: MKLSLSPPPYADAPVVVLISGLGGSGSYWLPQLAVLVQEYQVVCYDQRGTGNNPDTLAEDYSIAQMAAELHQALVAAGIERYAVVGHALGALVGMQLALDYPASVTVLVSVNGWLRINAHTRRCFQVREQLLHSGGAQAWVEAQPLFLYPADWMAARAPRLEAEDALALAHFQGKNNLLRRLNALKRADFSHHADRIRCPVQIICASDDLLVPTACSSELHAALPDSQKMVMRYGGHACNVTDPETFNALLLNGLASLLHHREAAL
What is the function of this protein?
Involved in pyrimidine catabolism.  May facilitate the hydrolysis of carbamate, a reaction that can also occur spontaneously.
What are the official names of this protein?
Putative carbamate hydrolase RutD, Aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Hydrolase RutD family.
Protein: NANR_SALNS
Sequence: MNAFDSQAEDSPTSLGRSLRRRPLARKKLSEMVEEELEQMIRRHEFGEGEQLPSERELMAFFNVGRPSVREALAALKRKGLVQINNGERARVSRPSADTIISELSGMAKDFLTHPGGIAHFEQLRLFFESSLVRYAAEHATDEQIALLAKALEINSQSLDDNALFIRSDVEFHRVLAEIPGNPIFMAIHVALLDWLIAARPSVPDRELHEHNNVSYQQHIVIVDAIRQRDPDKADRALQTHLNSVSATWHALGKKSQKMR
What is the function of this protein?
Transcriptional repressor that controls expression of the genes required for the catabolism of sialic acids.
What are the official names of this protein?
HTH-type transcriptional repressor NanR.
What is the protein family that this protein belongs to?
Belongs to the NanR family.
Protein: DF277_ARATH
Sequence: MSAQKIYLASLLLFICLVFPQSTAIVCNFEGHCVTSDDCINVCKSGEDPFLCVRSGPHKGMCCCLKTNGSVLE
What are the official names of this protein?
Putative defensin-like protein 277.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: P23_THEAN
Sequence: MNKYFKVFFFVLLTHALKSSLIFGQATLQKGLSLDIDKDSTATDRLVVKHLDSDKQGYKVYTFKKEGWEYVNVKHVYFGERLLRVGRDNDMRCDFVHYVKVFWKGDVAPFFIKMNYYNWAWVSTRLHFKLNPDLTWTEVTVLTLDENAEQGFTTLFKQKLDEFASQVGDDVLAKYKPFVDDPNKKRFDLKATDEKEETSKKKYVLMVVVVVVFVVVASLVVFLVKFCLK
What are the official names of this protein?
23 kDa piroplasm membrane protein, p23.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: QUEC_GLUDA
Sequence: MATSLTPADPLQEAAIVLFSGGQDSATCLAWALSRFGRVETVGFDYGQRHAVELACRARLRDGMAALDPDWATRLGQDHTLALDALGTVSDTALTRDAAITMNENGLPSTFVPGRNLIFLTFAAALAARRGARHIVGGMCETDYSGYPDCRDDTIKAMQVALNLGMASRYVLHTPLMWIDKAETWRMAEGLGGADLVELINRESHSCYLGVRDVMHPWGHGCGTCPACMLRRAGWERYVADGADA
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: DNAK_DICT6
Sequence: MAKIVGIDLGTTNSLIAYLEGGRPTIIPNAEGSRLTPSVVAFTKDGQLLVGEPAKRQAIVNAERTIKSIKRHMGTNYKVKIDDKEYTPQEISAMILRKLKKDAEAYLGEPIEKAVITVPAYFSDAQRQATKDAGAIAGLEVVRIINEPTAAALAYGLDKEGHQKILVFDLGGGTFDVSILEIGEGVFEVIATAGNNRLGGDDFDERIVNWLVEMFMEEHGINLKEDRTALQRLFEAAEKAKIELSSKLQTEINLPFIAMKGNTPLHISVTLTRAKFEELTYDLVEKTKEPTERALKDAGLSPSQIDKIILVGGATRMPCIQEWIKKHFGKEPQRNVNPDEAVALGAAIQAGVIGGEIRDIVLVDVTPLSLGIETLGGVFTKIIERNTPIPVSKSQIFTTAADYQTSVEIHVLQGERALAKDNISLGRFILDGIPPAPRGVPQIEVTFDIDVNGIVHVSARDKATGREQRITISNAIRLSEEEIKRMTEEAKRFEEEDRKRREEIETKNQAEHLIYTARKTLKDYGDKVSKDLVQRVEDKIKNLEELIKPERINVEQVKKGMEELTQALGEIGQFMYQSASAAGNPGQGQTNENPGGKTIDGDYKVN
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: MTND1_COPC7
Sequence: MRAYYFDNIPGDQRLPHDSGRPVSEDTLRKLNISYWRIELDGYLPKLNAVAEERGYKNRDFINVSKAGLGDSYEEKLKNFFSEHMHEDEEIRYVVDGSGFFDVRESPSDEWIRIGVEPGDLLVIPAGIYHRFTLDENNYIKAIRLFQDEPKWIPYNRSEETEVNPHRINYLREIGVGA
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase 1, Acireductone dioxygenase (Fe(2+)-requiring) 1, ARD' 1, Fe-ARD 1, Acireductone dioxygenase (Ni(2+)-requiring) 1, ARD 1, Ni-ARD 1.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NEAP1_ARATH
Sequence: MSYSEKTTVDPLLRDLDEKKESFRRNVVSLATELKQVRGRLVSQEQSFLKETITRKEAEKRGKNMEMEICKLQKRLEERNCQLEASASAADKFIKELEEFRLKLDTTKQTAEASADSAQSTKIQCSMLKQQLDDKTRSLREQEDRMTQLGHQLDDLQRGLSLRECSEKQLREEVRRIEREVTEAIAKAGIGGMDSELQKLLEDVSPMKFERMNRLVEVKDEEITKLKDEIRLMSGQWKHKTKELESQLEKQRRTDQDLKKKVLKLEFCLQEARSQTRKLQRKGERRDMEIKEIRDLISEKQNLNNESWDKQKFWDNSGFKIVVSMSMLMLVVVSKR
What are the official names of this protein?
Nuclear envelope-associated protein 1, AtNEAP1, Plant IF-like protein.
What are the subcellular locations of this protein?
Nucleus inner membrane; Single-pass membrane protein. Nucleus, nucleoplasm. Note=Colocalized with bZIP18 in the nucleoplasm.
Protein: KIFC1_MOUSE
Sequence: MDVQAQRPPLLEVKRNVELKAALVKSSSRVPLSASRLKRGPDQMEDALEPAKKRTRVMGAVTKVDTSRPRGPLLSTVSQTQGHTAAQKGPKKTGPRGCSAIGTVLRSQKPVPAAPAQKPGTSTAPVVVGKRAGKRPAWDLKGQLCDLNEELKRYREKTQTLELENRGLREQLREVQEQATTLGTERNTLEGELASVRSRAEQDQQRLETLSARVLELEECLGTRERLLQELQGERLQLQEERSTLSTQLEEQERRFQATEAALSSSQEEVVCLRQKTEAQVTLLAEQGDRLYGLEMERRRLHNQLQELKGNIRVFCRVRPVLEGESTPSPGFLVFPPGPAGPSDPPTGLSLSRSDDRRSTLTGAPAPTVRHDFSFDRVFPPGSKQEEVFEEIAMLVQSALDGYPVCIFAYGQTGSGKTFTMEGGPRGDPQLEGLIPRAMRHLFSVAQEMSGQGWTYSFVASYVEIYNETVRDLLATGPRKGQGGECEIRRASPGSEELTVTNARYVPVSCEKEVEALLHLAHQNRAVAHTAQNKRSSRSHSVFQLQISGEHAARGLQCGAPLNLVDLAGSERLDPGLHLGPGERDRLRETQAINSSLSTLGLVIMALSNKESHVPYRNSKLTYLLQNSLGGSAKMLMFVNISPLEENVSESLNSLRFASKVNQCVIGTAQANKK
What is the function of this protein?
Minus end-directed microtubule-dependent motor required for bipolar spindle formation (PubMed:16638812).  May contribute to movement of early endocytic vesicles (PubMed:17360972).  Regulates cilium formation and structure (PubMed:23807208).
What are the official names of this protein?
Kinesin-like protein KIFC1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. NCD subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Early endosome. Note=Associated with nucleus during interphase, centrosomes in early and spindle in later mitosis.
Protein: ATP6_PSET1
Sequence: MAAEEVTLSSHIQHHLTNAKMCSTDAGLAFNKACADSGFWTWHVDTLAWSIGLGLIFLWIFRSAAKKSTLGVPGKFQCFIEIIVEFVGDNVRDTFHGKSKLIAPLALTIFVWVFLMNLMDLIPVDFLPSFAGFVGETAFGMDSHDVYMKIVPTTDINMTSALALGVFILMVGFAIKIKGIGGFIKELTLHPFSSNNVFVQILLIPFNLLLELIALVSKPFSLALRLFGNLYAGELIFILIGAIGFMQLPLHFVWAVFHILVITLQAFLFMMLTIVYLSMASSDNH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SUB4B_COCP7
Sequence: MSILFKIFASTLAVVSVVNAGELLNFENERDIIRGSYIVVMKDGTSSSDLKSHMNWAANVHHGNLAKQGPSRSIGFQFSFDIGGWRGYSGKFDNDTLNAIVNNAHVKYVEPDRMASATVLKIQKNAPSWGLGRISHTFRGFKNYLYHSSAGEGVLAYVVDTGIDINHPEFEGRAEWGINVVDEVDTDEHGHGTHVAGTIGSKTFGVAKKVKLVAVKALGKDSRGPDSGIIAAMDWAVKHAKERGILGKAIMNLSLTGDTATALNEAAERAVEEGLFLGVAAGNNNRDAINESPASVETVCTAGASAENDEKASFSNFGSLRTSMAAPHVCGVAALLMSSEGIKAQEACDRIKKLARPAIRNPGNSTTNKLLYNKSGF
What is the function of this protein?
Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity.
What are the official names of this protein?
Subtilisin-like protease CPC735_012930.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PTH_CORDI
Sequence: MTSPYLIVGLGNLGPEYTKTRHNIGYMAIDELLTRTSPMPATLTVHKKTNTLVAETRLGTQKVIVAKPRAFMNVTGPSVRKLADFFTVDRNRIVVLYDDLDLEFGAIKFRHGGGDHGHNGLKSITQALGTKDYIRGGIGIGRPPGRMAPKSFVLKPFSKIEQSELPIVCADAADEVEKITTSEL
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.