PharMolix/UniProtQA huggingface dataset:
Protein: GDO1_PSEAC
Sequence: MSFTEKPAVTKERKEFYSKLESHDLAPLWEVLNEVVTTKPKSNCAPHLWEFEVAKEFLMEAGTLITAKEAERRVLILENPGLKGLSRITTSLYAGLQLILPGEVAPTHRHSQSALRFVVDGGGACTSVDGERTTMQVGDFVITPPWAWHDHVNDSDKPMIWMDGLDLPMVTLFDTSFAEGYGEDIQEITRPNGDSLARYGANMLPVDFKQKGLSSPIFNYPYERSREALEAMKKANEWDPCHGLKMQYINPLDGMAAMPTISSFIQLLPKEFRTQTYRSTDATVFSVIEGQGKTRIGDKVFFWKAKDTFVVPSWYPVEHEASSDAVLFSYSDRVAQQKLGFWRESRN
What is the function of this protein?
Involved in the degradation of gentisate (PubMed:10049846).  Catalyzes the conversion of gentisate (2,5-dihydroxybenzoate) to maleylpyruvate.  Exhibits broad substrate specificities towards alkyl and halogenated gentisates (PubMed:10049846, PubMed:16237038).
What are the official names of this protein?
Gentisate 1,2 dioxygenase 1, GDOI.
What is the protein family that this protein belongs to?
Belongs to the gentisate 1,2-dioxygenase family.
Protein: METK2_HUMAN
Sequence: MNGQLNGFHEAFIEEGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVAKTGMILLAGEITSRAAVDYQKVVREAVKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDTIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVIVRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.  The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
What are the official names of this protein?
S-adenosylmethionine synthase isoform type-2, AdoMet synthase 2, Methionine adenosyltransferase 2, MAT 2, Methionine adenosyltransferase II, MAT-II.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
Protein: MGT4A_BOVIN
Sequence: MRLRNGTVATVLAFITSFLTLSWYTTWQNGKEKVIAYQREFLALKERLRIAEHRISQRSSELSAIVQQFKRVEAETNRSKDPVNKFSDDTLKILKELTSKKSLQVPSIYYHLPHLLQNEGSLQPAVQIGNGRTGVSIVMGIPTVKREVKSYLIETLHSLIDNLYPEEKLDCVIVVFIGETDTDYVNGVVANLEKEFSKEISSGLVEIISPPESYYPDLTNLKETFGDSKERVRWRTKQNLDYCFLMMYAQEKGTYYIQLEDDIIVKQNYFNTIKNFALQLSSEEWMILEFSQLGFIGKMFQAPDLTLIVEFIFMFYKEKPIDWLLDHILWVKVCNPEKDAKHCDRQKANLRIRFRPSLFQHVGLHSSLTGKIQKLTDKDYMKPLLLKIHVNPPAEVSTSLKVYQGHTLEKTYMGEDFFWAITPVAGDYILFKFDKPVNVESYLFHSGNQDHPGDILLNTTVEVLPLKSEGLDISKETKDKRLEDGYFRIGKFENGVAEGMVDPSLNPISAFRLSVIQNSAVWAILNEIHIKKVTN
What is the function of this protein?
Glycosyltransferase that catalyze the transfer of GlcNAc from UDP-GlcNAc to the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans through a beta1-4 linkage and participates in the production of tri- and tetra-antennary N-linked sugar chains (PubMed:9278430, PubMed:9565571).  Involved in glucose transport by mediating SLC2A2/GLUT2 glycosylation, thereby controlling cell-surface expression of SLC2A2 in pancreatic beta cells (By similarity).
What are the official names of this protein?
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A, N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVa, GlcNAc-T IVa, GnT-IVa, N-acetylglucosaminyltransferase IVa, UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVa.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 54 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Alpha-1,3-mannosyl-glycoprotein 4-beta-N- acetylglucosaminyltransferase A soluble form]: Secreted.
Protein: GSA_THIDA
Sequence: MSRNEALFEASQKVIPGGVNSPVRAFRSVGGTPVFFSRARGSRVWDADGREYIDYVGSWGPAILGHAHPGTVKAVQDAAANGLSFGAPSEAELTIATRITELLPSVEKVRLVSSGTEATMSAIRLARGFTGRSKFIKFEGCYHGHADFLLVKAGSGALTFGNPTSAGVPPEVAAQTIVLDYNDVAGLERTFAEIGDEIACIIVEPFAGNMNLVKPSAEFMAAMRRLCDEHGALLIFDEVMTGFRVDLGCAQKLLGIRPDLTTLGKVIGGGMPVGAFGGRADVMDALAPVGPVYQAGTLSGNPVAVAAGLATLASVSEPGFYPALAARTEKLVKGLTAAAREAGVTFCADSVGGMFGLYFAAEPPASFAEVMRCDKEKFNRFFHAMLDHGVYLAPSAFEAGFVSAAHSDADIDATVAAAREVFRTL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAE_STRMU
Sequence: MTKIIGITGGIASGKSTITNYLRQKGYQVIDADQVVHDLQANGGRLYQALVNWLGTAILNEAGELNRPKLSQLIFSSPDNLAKSSQLQNAIIRQELETRRDQLAKTEAIFFMDIPLLIEQNYRDWFDEIWLIAVSPETQIKRLKQRNGYSQEEAQQRLASQMPLQAKKVYADQIIDNNKTVENTKMQVDSQLRRLQNE
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LYS_BPGA
Sequence: MGLKAKHKENLCSDSERSKRLYVWIALAIVLSDFTSIFSHWIWGLLILYLQTLMDLPTFVMNV
What is the function of this protein?
Induces the formation of specific membrane adhesion sites between the inner and outer membranes, apparently leading to host cell lysis.  Lysis may be performed via activation of host murein hydrolases.
What are the official names of this protein?
Lysis protein.
What are the subcellular locations of this protein?
Host cell inner membrane; Single-pass membrane protein. Host cell outer membrane; Single-pass membrane protein.
Protein: SMG_YERPA
Sequence: MFDVLIYLFETYMHNEPEMLVDQDKITDDLADAGFYREDINNALNWLEVLADLQEGQKAPYLYTADPQALRIYTVEECRRLGAACRGFILFLEQIQVLQFDTREMVIDRIMALDSPEIDLEDLKWVVLMVLFNIPGYENAYKQMEELLFEVNDGYLH
What are the official names of this protein?
Protein Smg.
What is the protein family that this protein belongs to?
Belongs to the Smg family.
Protein: CDT1_YEAST
Sequence: MSGTANSRRKEVLRVPVIDLNRVSDEEQLLPVVRAILLQHDTFLLKNYANKAVLDALLAGLTTKDLPDTSQGFDANFTGTLPLEDDVWLEQYIFDTDPQLRFDRKCRNESLCSIYSRLFKLGLFFAQLCVKSVVSSAELQDCISTSHYATKLTRYFNDNGSTHDGADAGATVLPTGDDFQYLFERDYVTFLPTGVLTIFPCAKAIRYKPSTMATTDNSWVSIDEPDCLLFHTGTLLARWSQGMHTTSPLQIDPRANIVSLTIWPPLTTPISSKGEGTIANHLLEQQIKAFPKVAQQYYPRELSILRLQDAMKFVKELFTVCETVLSLNALSRSTGVPPELHVLLPQISSMMKRKIVQDDILKLLTIWSDAYVVELNSRGELTMNLPKRDNLTTLTNKSRTLAFVERAESWYQQVIASKDEIMTDVPAFKINKRRSSSNSKTVLSSKVQTKSSNANALNNSRYLANSKENFMYKEKMPDSQANLMDRLRERERRSAALLSQRQKRYQQFLAMKMTQVFDILFSLTRGQPYTETYLSSLIVDSLQDSNNPIGTKEASEILAGLQGILPMDISVHQVDGGLKVYRWNSLDKNRFSKLLQIHKSKQQD
What is the function of this protein?
DNA replication licensing factor, required for pre-replication complex assembly.  Faithful duplication of the genetic material requires 'once per cell cycle' DNA replication initiation and elongation.  Central to this control is the tightly regulated formation of prereplicative complexes (preRCs) at future origins of DNA replication.  Required for the recruitment of the MCM2-7 helicase complex to the replication origins.
What are the official names of this protein?
Cell division cycle protein CDT1, SIC1 indispensable protein 2, Topoisomerase-A hypersensitive protein 11.
What is the protein family that this protein belongs to?
Belongs to the Cdt1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Undergoes cell cycle- dependent changes in its nuclear localization. Exits the nucleus and remains in the cytoplasm during S phase through early mitosis, and re- accumulates in the nucleus around the end of mitosis.
Protein: PDXH_BURCJ
Sequence: MTTLADLRINYSRASLDEADAAPDPFAQFDRWFKEALAAKLPEPNTMTLATVGADGRPSARIVLIKGVDERGFVFFTNYESRKGHDLAVHPQAALLFYWIELERQVRIEGRIEKTSAEESDRYFASRPLGSRIGAWASEQSAVIDSRATLEAREKAVSERYGDNPPRPPHWGGYRLVPDSIEFWQGRPSRLHDRLLYTRDAAASPGWTISRLSP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: SHSA6_MOUSE
Sequence: MALRRLLLPPLLLSLLLSLASLHLPPGADAARGRSGNRTLNAGAVGGRRAGGALARGGRELNSTARASGVPEAGSRRGQSAAAAAAAAAAASATVTYETCWGYYDVSGQYDKEFECNNSESGYLYCCGTCYYRFCCKKRHEKLDQRQCTNYQSPVWVQTPSTKVVSPGPENKYDPEKDKTNFTVYITCGVIAFVIVAGVFAKVSYDKAHRPPREMNIHRALADILRQQGPIPIAHCERETISAIDTSPKENTPVRSTSKNHYTPVRTAKQTPGDRQYNHPILSSATQTPTHEKPRMNNILTSATEPYDLSFSRSYQNLAHLPPSYESAVKTNPSKYSSLKRLTDKEADEYYMRRRHLPDLAARGTLPLNVIQMSQQKPLPRERPRRPIRAMSQDRVLSPRRGLPDEFGMPYDRILSDEQLLSTERLHSQDPLLSPERTAFPEQSLSRAISHTDVFVSTPVLDRYRMTKMHSHPSASNNSYATLGQSQTAAKRHAFASRRHNTVEQLHYIPGHHTCYTASKTEVTV
What is the function of this protein?
Involved in maintenance of high-frequency synaptic transmission at hippocampal CA3-CA1 synapses.  Regulates AMPA-type glutamate receptor (AMPAR) immobilization at postsynaptic density keeping the channels in an activated state in the presence of glutamate and preventing synaptic depression (PubMed:26931375).  May play a role in self-renewal and differentiation of spermatogonial stem cells by inhibiting canonical Wnt signaling pathway (PubMed:28196692).
What are the official names of this protein?
Protein shisa-6, Cystine-knot AMPAR modulating protein of 52 kDa, CKAMP52, Shisa family member 6.
What is the protein family that this protein belongs to?
Belongs to the shisa family.
What are the subcellular locations of this protein?
Postsynaptic density membrane; Single-pass type I membrane protein.
Protein: GM4D_SHIFL
Sequence: MSKVALITGVTGQDGSYLAEFLLEKGYEVHGIKRRASSFNTERVDHIYQDPHTCNPKFHLHYGDLSDTSNLTRILREVQPDEVYNLGAMSHVAVSFESPEYTADVDAMGTLRLLEAIRFLGLEKKTRFYQASTSELYGLVQEIPQKETTPFYPRSPYAVAKLYAYWITVNYRESYGMYACNGILFNHESPRRGETFVTRKITRAIANIAQGLESCLYLGNMDSLRDWGHAKDYVKMQWMMLQQEQPEDFVIATGVQYSVRQFVEMAAAQLGIKLRFEGTGVEEKGIVVSVTGHDAPGVKPGDVIIAVDPRYFRPAEVETLLGDPTKAHEKLGWKPEITLREMVSEMVANDLEAAKKHSLLKSHGYDVAIALES
What is the function of this protein?
Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
What are the official names of this protein?
GDP-mannose 4,6-dehydratase, GDP-D-mannose dehydratase.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
Protein: HEM3_CORGB
Sequence: MTLKIGTRGSKLATTQAGTIRDQLKYFGRDAELHIVTTPGDVNMSPVERIGVGVFTQALRDVLHAGECDVAVHSMKDLPTAADPRFHLVVPTRADSREALIARDGLTLAELPEGAKVGTSAPRRISQLKAIRPDLEILPLRGNIDTRMGKVTSGELDAVMLAYAGLTRVGMQDRATEVFDADIIMPAPAQGALAIECRADDTETVRALNMLMHADTFVSAVAERTVLNRLEAGCTAPVAAHATLDGYSGDTMTLTAGVYALDGSDQLVFSAEGDGARPEELGELVAQQLIDAGAANLLGDRS
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: LSPA_GEOKA
Sequence: MAYYWIAAAVVILDQWTKWLVVRYMQLGESIPIIDNVLYITSHRNRGAAWGMLEGQFWLFYLITVIVVAAIVIYIRRLKPSERLAGVGLGLMLGGAIGNFLDRVFRKEVVDFIHAYIGTYSFPVFNVADSALTVGVILLFVHMFFFATPEKGNE
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YVDR_BACSU
Sequence: MAWFLLVIAGIEEIIAAIAMKYIDGTRKKWPIIVMTVGFGLSFYCLSQAMIVLPAGVAYAVWTGIGSIGVSAVGLIWFKERFQLSQVISLCLILAGVIGLRLTSSS
What are the official names of this protein?
Uncharacterized membrane protein YvdR.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TDH_IDILO
Sequence: MKALSKLHAKPGIWMTDVEKPECGYNDLLIKIKKTAICGTDVHIYKWDDWSQKTIPVPMVVGHEYVGEVAAMGDGVRGFEIGDRVSGEGHITCGHCRNCRAGRRHLCRNTYGVGVNRPGAFAEYLALPAENAFKLPDDVTDEMAAVFDPFGNAVHTALAFDLVGEDVLITGAGPIGIMAAAVARHVGARHVVITDVNEYRLDLARKMGVTRAVDVSKEKLSDVMTELGMKEGFDVGLEMSGVPSAFSQMLETMNHGGKIAMLGIPPENIAIDWNQVIFKGLVIKGIYGREMFETWYKMASLLQSGLDISPILTHEMPIDDFEKGFETMISGQSGKVILNWD
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUD_LACLM
Sequence: MEKFTIYKGTSVPLMNDNIDTDQIIPKQFLKAIDKKGFGKNLFYEWRYSKDYEENPDFMLNKPQYRKASLLISGDNFGSGSSREHAAWALADYGFRAIIAGSYSDIFYNNSLKNGLLPIVQPKEALKSLAQLSSQEEITIDLPHQLIQTSTENFYFEIDPIWKDKLINGLDDIGITLQYEQAITAYEQKHQ
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: GDX_SALCH
Sequence: MSWIVLLIAGLLEVVWAIGLKYTHGFTRLTPSIITIAAMIVSIAMLSWAMRTLPVGTAYAVWTGIGAVGAAITGILLLGESASPARLLSLGLIVAGIIGLKLSTH
What is the function of this protein?
Guanidinium ion exporter.  Couples guanidinium export to the proton motive force, exchanging one guanidinium ion for two protons.
What are the official names of this protein?
Guanidinium exporter.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Gdx/SugE subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YJZJ_BACSU
Sequence: MYPIQIVFSENPIDQRHLGQSGGTISFTACGLPVFHFETQEQFQAYMMLKGEAAYNEKR
What are the official names of this protein?
Uncharacterized protein YjzJ.
Protein: ADAL_MOUSE
Sequence: MEAGQQWPGKTDFYLQLPKVELHAHLNGSISSSTMKKLIAKKPHLNVHGHMTMIDKGKKRTLQECFQMFQVIHQLTTSAEDILMVTKDVIKEFADDGVKYLELRSTPREENATGMTRKTYVESVLEGIKQCKQENLDIDVRYLMAIDRRGGPTIARETVELAKEFFLSTENTVLGLDLSGDPTIGQANDFLEPLLEAKKAGLKLALHLAEIPNREKENQMLLSLLPDRIGHGTFLSASEAGALDQVDFVRQHQIPLELCLTSNIKSQTVPSYDQHHFGFWYSIAHPSVICTDDKGVFATYLSQEYQLAAETFNLTPFQVWDLSYESINYIFACDNTRSELRKRWTHLKQKVLNCNEVNYF
What is the function of this protein?
Catalyzes the hydrolysis of the free cytosolic methylated adenosine nucleotide N(6)-methyl-AMP (N6-mAMP) to produce inositol monophosphate (IMP) and methylamine.  Is required for the catabolism of cytosolic N6-mAMP, which is derived from the degradation of mRNA containing N6-methylated adenine (m6A).
What are the official names of this protein?
Adenosine deaminase-like protein.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
Protein: SIM30_HUMAN
Sequence: MTSVSTQLSLVLMSLLLVLPVVEAVEAGDAIALLLGVVLSITGICACLGVYARKRNGQM
What are the official names of this protein?
Small integral membrane protein 30.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: REPA2_ECOLX
Sequence: MTDLHQTYYRQVKNPNPVFTPREGAGTLKFCEKLMEKAVGFTSRFDFAIHVAHARSRGLRRRMPPVLRRRAIDALLQGLCFHYDPLANRVQCSITTLAIECGLATESAAGKLSITRATRALTFLSELGLITYQTEYDPLIGCYIPTDITFTSALFAALDVSEEAVAAARRSRVVWENKQRKKQGLDTLGMDELIAKAWRFVRERFRSYQTELKSRGIKRARARRDADRERQDIVTLVKRQLTREIAEGRFTANREAVKREVERRVKERMILSRNRNYSRLATASP
What is the function of this protein?
This protein is essential for plasmid replication; it is involved in copy control functions.
What are the official names of this protein?
Replication initiation protein.
What is the protein family that this protein belongs to?
Belongs to the IncFII RepA family.
Protein: Y165_METJA
Sequence: MGKNLRDLLLAFKNGDISLDEIEKQIKLNYYEEIEERLKLDINRQFRTGVPEVVYGKGKDIDEIIKATLKLVEKNGIALATKIEDIEKLSDEIRKWNLKNYDIKINKKAKTLIIKNKNYEVKKIGKVGILTAGTSDIPVAEEAKDTLEIMGVEAITAYDVGIAGIHRLFPALKRMIEEDVCCIIVVAGMEGALPSVIASMVDIPVIGVPTSTSYGIKITPLLTMLHSCSPGIAVVNIDNGFGAGVFAGLIAKIMHK
What are the official names of this protein?
Uncharacterized protein MJ0165.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HS178_ORYSJ
Sequence: MSLVLSRMLLDRFFPGAGGVVAGEARPPMDWRETPVAHVFEMDLPGLAKDQVAVEVVDGHILRVRAGGEHEDANNAAKAGKASGEEEEENDGVRWHCRERAAGRRRAAVTQFRLPEDAAADEASARMADGVLTVTVPKRKGKKRHAGNGKAAGDDKPVCCRFWP
What are the official names of this protein?
17.8 kDa heat shock protein, OsHsp17.8.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYY_METCA
Sequence: MNDVITQLLRGTHEVLRLEELQKRIESGKPLRIKAGFDPTAPDLHLGHTVLLNKLKQFQDLGHETIFLIGDFTGMIGDPTGKNVTRRPLTRDEVIENAKTYEEQIYKVLCPERTLVMFNSSWMNAMTSADLIQLAAKHTVARMLERDDFAKRYAGGQPISIHEFLYPLIQGYDSVALKADVELGGADQKFNLLVGRHLQEIYGQTPQVVMTMPILEGLDGIQKMSKSLGNYIGIADPPDDMFGKIMSISDDLMWRYYDLLSFAPLAEVARWRRECSEGANPRDVKVRLGQEIVERFHGASAARKALENFEARHRDNAVPDDLVEQVIAVPDGGYPIANLVHDLALTASTSEALRLIKQGGIKIDGERLEDPKCRMTAGGTHIIQVGKRKFAKIRLTP
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOX_LACJE
Sequence: MTVYYKGFPQSDRNEAIKMVNVDELEDRVRKVMPEAAYYYIASGSENEWTWRNNTAAFNHFQIVPRSLTNMDNPSTETQFMGMDLKTPIMICPIACHGIAHKDAEVATAQGAKAAGALFSSSTYANRSVEDIATATGDSPKFFQLYLSKDWDFNKMVFDAVKSAGYKGIMLTVDALVSGYREANLRTNFTFPVPLDFFTRYVGAEGEGMSVAQMYANSAQKIGPADVAKIKEMSGLPVFVKGVMNAEDAYMAIGAGADGIVVSNHGGREIDTAPATIDMLPEIAAAVNGRVPIILDSGVRRGSHVFKALALGADLVGIGRPFLYGLALGGAKGVESVINQINNEFKILMQLTGCKTVEDVKHADIRQINYTADNLPSNTDPSVRRAYPVTKENQMEGTQDAATGASKH
What is the function of this protein?
Oxidase that catalyzes the oxidation of a broad range of 2-hydroxyacids in vitro, such as (S)-lactate, 2-hydroxyoctanoate, and to a lesser extent glycolate, mandelate and 2-hydroxyoctadecanoate, to the corresponding 2-oxoacids, with a reduction of O2 to H2O2 (PubMed:34555022).  May be involved in the utilization of L-lactate as an energy source for growth (By similarity).
What are the official names of this protein?
L-lactate oxidase, LOX, (S)-2-hydroxy-acid oxidase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
Protein: MSCL_LACGA
Sequence: MIKEFKEFISRGNMMDLAVGVIIGAAFTAIVNSLVKDLINPLIGLFIGKIDLSNLKFTVGEATFKYGSFLNAVINFLIIALVVFFLIKLVNKMMPKKEVEEDDPTPTNEELYLRQIRDLLQEKTK
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PRTA_STRGR
Sequence: MTFKRFSPLSSTSRYARLLAVASGLVAAAALATPSAVAAPEAESKATVSQLADASSAILAADVAGTAWYTEASTGKIVLTADSTVSKAELAKVSNALAGSKAKLTVKRAEGKFTPLIAGGEAITTGGSRCSLGFNVSVNGVAHALTAGHCTNISASWSIGTRTGTSFPNNDYGIIRHSNPAAADGRVYLYNGSYQDITTAGNAFVGQAVQRSGSTTGLRSGSVTGLNATVNYGSSGIVYGMIQTNVCAEPGDSGGSLFAGSTALGLTSGGSGNCRTGGTTFYQPVTEALSAYGATVL
What is the function of this protein?
Has a primary specificity for large aliphatic or aromatic amino acids.
What are the official names of this protein?
Streptogrisin-A, Pronase enzyme A, SGPA, Serine protease A.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
Protein: FWDC_METTM
Sequence: MSEIILTPKEQPEVPLEAPNIKPDVFAGKSIDEIKNIQIMYGNEVVKLGDFFEVSGEPADAASDIKIIIDGDVYNTKRIGQEMTAGEILVKGNVNMYVGAGMKGGRITVEGNAASWAGQDMRGGELEILGNAADYVGSSYRGDWRGMSGGVITVHGNAGNEIGEYMNGGKIIIKGDVNIMPGIHMNNGLIIIEGNAVARVGGEMAGGTIIVKGMIQEFLPGFKYLGVEKDIEVNGETFPGAFYKFEGDHAIKGAKGIVYAAVGCNGHIEP
What is the function of this protein?
Catalyzes the reversible oxidation of CO(2) and methanofuran (MFR) to N-formylmethanofuran (CHO-MFR).  Can only oxidize formylmethanofuran.  This enzyme is oxygen-labile.
What are the official names of this protein?
Tungsten-containing formylmethanofuran dehydrogenase 2 subunit C, Tungsten-containing formylmethanofuran dehydrogenase II subunit C.
What is the protein family that this protein belongs to?
Belongs to the FwdC/FmdC family.
Protein: RL28_LACAC
Sequence: MAKDYVTGKKTTFGNKRSHSLNPTRRAWKPNLQKVRILVDGKPKRVWVSTKALKSGKVTRV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: MGLL_HUMAN
Sequence: MPEESSPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTNSVFHEINMWVSQRTATAGTASPP
What is the function of this protein?
Converts monoacylglycerides to free fatty acids and glycerol (PubMed:19029917, PubMed:20079333, PubMed:21049984, PubMed:22969151, PubMed:24368842).  Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain (PubMed:19029917, PubMed:20079333, PubMed:21049984, PubMed:22969151, PubMed:24368842).  Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth (PubMed:20079333).
What are the official names of this protein?
Monoglyceride lipase, MGL, HU-K5, Lysophospholipase homolog, Lysophospholipase-like, Monoacylglycerol lipase, MAGL.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Monoacylglycerol lipase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Membrane; Peripheral membrane protein.