PharMolix/UniProtQA huggingface dataset:
Protein: SEL10_CAEEL
Sequence: MWPRNDVHMDDGSMTPEDQEPVTDNDMEYNDNGEESSYSNGSSSSYNADKLSSSRPLQHKLDLSASPSRNNDLNPRVEHLIALFKDLSSAEQMDAFTRLLQESNMTNIRQLRAIIEPHFQRDFLSCLPVELGMKILHNLTGYDLLKVAQVSKNWKLISEIDKIWKSLGVEEFKHHPDPTDRVTGAWQGTAIAAGVTIPDHIQPCDLNVHRFLKLQKFGDIFERAADKSRYLRADKIEKNWNANPIMGSAVLRGHEDHVITCMQIHDDVLVTGSDDNTLKVWCIDKGEVMYTLVGHTGGVWTSQISQCGRYIVSGSTDRTVKVWSTVDGSLLHTLQGHTSTVRCMAMAGSILVTGSRDTTLRVWDVESGRHLATLHGHHAAVRCVQFDGTTVVSGGYDFTVKIWNAHTGRCIRTLTGHNNRVYSLLFESERSIVCSGSLDTSIRVWDFTRPEGQECVALLQGHTSLTSGMQLRGNILVSCNADSHVRVWDIHEGTCVHMLSGHRSAITSLQWFGRNMVATSSDDGTVKLWDIERGALIRDLVTLDSGGNGGCIWRLCSTSTMLACAVGSRNNTEETKVILLDFDAVYP
What is the function of this protein?
Probable substrate recognition component of SCF (SKP1-CUL-F-box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:17626846).  Regulates synapse elimination in early development in the motor neuron HSNL (PubMed:17626846).  Cell autonomous negative regulator of lin-12/Notch-mediated signaling, with respect to lin-12 activity in cell fate decisions and tumorigenesis (PubMed:9389650).  May target the intracellular domains of lin-12/Notch proteins for ubiquitin-dependent degradation (PubMed:9389650).  Involved in sex determination by promoting female development (PubMed:15306688, PubMed:18718460).  Potential regulator of presenilin (PubMed:9861048).  May have a role in egg laying (PubMed:8293978, PubMed:15306688).  Regulates zyg-1 levels (possibly redundantly with lin-23) to control centrosome duplication during mitosis (PubMed:22623721).  Negatively regulates lin-45 activity and protein stability, probably by targeting it for ubiquitination and proteasomal degradation (PubMed:23154983).
What are the official names of this protein?
F-box/WD repeat-containing protein sel-10, Egg laying defective protein 41, Suppressor/enhancer of lin-12 protein 10.
What are the subcellular locations of this protein?
Cell projection, axon. Cytoplasm. Note=Expressed throughout the axon throughout development.
Protein: IFN17_HUMAN
Sequence: MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFGLPQEEFDGNQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNNLEACVIQEVGMEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTNLQKILRRKD
What is the function of this protein?
Produced by macrophages, IFN-alpha have antiviral activities.  Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
What are the official names of this protein?
Interferon alpha-17, IFN-alpha-17, Interferon alpha-88, Interferon alpha-I', LeIF I, Interferon alpha-T.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta interferon family.
What are the subcellular locations of this protein?
Secreted.
Protein: MURD_STRPI
Sequence: MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFEDNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTEVELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASDKDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAADFLVLNFNQDLAKDLTSKTEATVIPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPGSHNVENALATIAVAKLRDVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNILATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKAGVAYVEATDIADATRKAYELAIQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_THISH
Sequence: MANYSTSEFKSGLKILMDGDPYAIIENEFVKPGKGQAFNRVKVRNLKTGRVLEKTFKSGDSVEAADVMDTNMQYLYTDGEFWHFMVPDTFEQHAAGEAAVADAIKWLKEQDMCVVTLWNGVPLAVSPPNFVELTITQCDPGVRGDTAQGGTKPATLETGAVVKVPLFVEEGEKVRVDTRTGEYVSRV
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHAS_ECOUT
Sequence: MTVLHSVDFFPSGNASVAIEPRLPQADFPEHHHDFHEIVIVEHGTGIHVFNGQPYTITGGTVCFVRDHDRHLYEHTDNLCLTNVLYRSPDRFQFLAGLNQLLPQEQDGQYPSHWRVNHSVLQQVRQLVAQMEQQEEENDLPSTASREILFMQLLLLLRKSSLQENLENSASRLNLLLAWLEDHFADEVNWDAVADQFSLSLRTLHRQLKQKTGLTPQRYLNRLRLMKARHLLRHSEASVTDIAYRCGFSDSNHFSTLFRREFNWSPRDIRQGRDGFLQ
What is the function of this protein?
Activates expression of the rhaBAD and rhaT operons.
What are the official names of this protein?
HTH-type transcriptional activator RhaS, L-rhamnose operon regulatory protein RhaS.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYSY_BACMO
Sequence: MTQFDKQYNSIIKEIIKNGISDEEFDVRTKWESDGTPAHTLSIITKQMRFDNSEVPILTTKKVAWKTAIKELLWIWQLKSNDVTELNKMGVHIWDQWKQEDGSIGHAYGFQLAKKNRNLNGEKVDQVDYLLHQLKNNPSSRRHITMLWNPDELDSMALTPCVYETQWYVKQGKLHLEVRARSNDMALGNPFNVFQYNVLQRMIAQVTGYELGEYIFNIGDCHVYTRHIDNLKIQMEREQFEAPKLWINPEVKDFYDFTIDDFKLINYKHGDRLSFEVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_COXB1
Sequence: MADMSVKQLADLVRTTPERLLEQLKEAGVAITHVDQTISDEEKRKLLLHLKTSHSTETGKKRSKIVLKRKKLSVVKSGKKSVNVEIRSKRTYTKPVVEQKRETEPAPTQEVPLTSDTTNLNEKAEVNVATLEKAVEAEVKEEAKKTPSEKKETPKKGPRKETRRSRKPDKEDKWEREELHMTKLVEERRRRHKPAHMPDSDNASAKLEQGFARPTAPVVREVALPESITVADLAQKMSVKAAEVIKAMMKLGAMVTINQRIDQETAAIVVEEMGHKPKLIKEDVLEENLVATLGEQTGEAVPRAPVVTIMGHVDHGKTSLLDYIRRTKVTSTEAGGITQHIGAYHVETELGMITFLDTPGHEAFTAMRARGAKCTDIVVLVVAADDGVMPQTVEAIQHARAAKVPVVVAVNKIDKPEADPERIKTELSTHDVLPEEWGGDTMFQPISAKTGEGIDALLERILLQAEVLELKAVDNGPARGMVVESRLDRGRGPVATVLVTSGELHLGDILLVGREYGRVRAMIGDDGRPCESAGPSMPVEVLGLSGTPVAGEEAIVVPDERKAREIARFRQGKYREVRLAKKQTAHLERIFDRMGEGKQNTLNIVLKADVQGSLEALTEALNKLSTDEVKVNIIASGVGGITESDVNLAIASDAVVIGFNVRADAPTRVLVEREGVDLRYYSIIYDLIDEVKKALSGLLAPEFEEKIVGLAEVRDVFRSSKIGAIAGCMVVEGVVRRHLPIRVLRDNVVIYEGQLESLRRYKEDVAEVRQGTECGIGVKNYNDVKVGDQIEVYEKTQVHRTIA
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DLTC1_LACPL
Sequence: MTMDDTKATVLSILADLTGEDVSSNMDVNLFDEGILDSMGSVQLLLELQNQLGIEVPVSEFQRSEWDTPAKIVAKVENLQ
What is the function of this protein?
Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA).  The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA.  The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanyl carrier protein 1, DCP 1, D-alanine--poly(phosphoribitol) ligase subunit 2-1.
What is the protein family that this protein belongs to?
Belongs to the DltC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCS2_MYCA1
Sequence: MSSVPARRGDAHIDFARSPRPTIGVEWEFALVDAQTRDLSNEATAVIAEIGENPRVHKELLRNTVEVVSGICRTVPEAMEDLRQTLGPARRIVRDRGMELFCAGAHPFAQWTTQKLTDAPRYAELIKRTQWWGRQMLIWGVHVHVGISSPNKVMPIMTSLLNYYPHLLALSASSPWWTGVDTGYASNRAMMFQQLPTAGLPFQFQTWAEFEGFVYDQKKTGIIDHVDEVRWDIRPSPHLGTLEMRICDGVSNLHELAALVALTHCLVVDLDRRLEADESLPTMPPWHHQENKWRAARYGLDAVIILDADSNERLVTEDLDDVLNRLEPVARKLQCADELAAVADIPRHGASYQRQRRVAEEHDGDLRAVVDALVAELEI
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: AACS_CHICK
Sequence: MSREPEIMESQVMWEPDSKRNTHMDRFRAAVAGSCGLRLANYNDLYQWSVESFADFWAEFWKYSNIVCSRLYDEVVDTSKSIADVPEWFKGSRLNYAENLLKHKDNDKIALYAAKEGKEEILKVTFEELRQAVALYAAAMRKMGVKIGDRVVGYLPNSIHAVEAMLAAASIGAIWSSTSPDFGINGVLDRFSQIQPKLIFSVEAVVYNGKEHNHLEKLLSVVKGLPDLKKVVVIPYVSSRETIDISKIPNSVFLEDFLATGKGDQAPQLEFEQLPFSHPLFIMYSSGTTGAPKCMVHSAGGTLIQHLKEHILHGNMSSNDIIMYYTTTGWMMWNWLVTALATGASVVLYDGSPLVPSPNVLWDLIDRLGITILGTGAKWLAVLEEKNLKPCETHNLQTLHTILSTGSPLKSQSYEYVYKHIKSSVLLGSISGGTDIISCFMGQNVTIPVYKGEIQARNLGMAVEAWNDEGKPVWGESGELVCTKPIPCQPTHFWNDENGSKYRKAYFSKFPGVWAHGDYCKINPKTGGIVMLGRSDGTLNPNGVRFGSSEIYNIVEAFEEVSDSLCVPQYNKDGEERVILFLKMASNHAFSEDLVKRIRDAIRVALSARHVPSLILETKGIPYTINGKKVEVAVKQIIAGKEVEQRGAFSNPETLDLYQNIPELQNF
What is the function of this protein?
Converts acetoacetate to acetoacetyl-CoA in the cytosol (By similarity).  Ketone body-utilizing enzyme, responsible for the synthesis of cholesterol and fatty acids (By similarity).
What are the official names of this protein?
Acetoacetyl-CoA synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: PSAM_SYNJA
Sequence: MTDAQVFTILAIALVPAVMAALLGSALARS
What are the official names of this protein?
Photosystem I reaction center subunit XII, PSI-M.
What is the protein family that this protein belongs to?
Belongs to the PsaM family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: RLMN_CARHZ
Sequence: MRAFLDLNSEEIVAWLKENNEKSFRLKQINEWIFKHGELDFNKMTNLPVRLREKLKENFLLPSLKIIHSKKSRDGQSIKYLLKLKDNLGIEAVLLKYRYGNTVCLSTQVGCKMGCKFCATGLGGFSRNLTAGEMIEQILVLKASSSEKITRVVLMGSGEPLDNFTEVLKFMRKINEKDCLNISYRKITVSTCGMVPQIKALAEEKLPVTLAISLHAPDDALRNELIPINKRWGLAELLDAAWYFIDKTGRRVSFEYALIENVNDTVEHALKLAQLLQRKLVHVNLIPYNTIEKRNFKTPSVEKINKFKEVLKRAGIPVTVRRELGDEIDGACGQLKAKYFEV
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S406_ARATH
Sequence: MAKGRKPTTMNRSDRYLGSYTYGDSHGNSVTDELELGEEDIWSPAVIHDDTTENEESYGTWNLRATLGKNGRVGGLSLAFEGSLVAPPSSSPMIVQKIHGGGGEGEEDRRKLASSAPVNVPDWSKIYRVDSVESIHELDDEDDEDEESGMMPPHEYLAKSQARRSRKIGGGGASVFDGVGRTLKGRELRRVRDAIWSQTGFYG
What are the official names of this protein?
Protein S40-6, AtS40-6.
What is the protein family that this protein belongs to?
Belongs to the senescence regulator S40 family.
Protein: AOX1A_ARATH
Sequence: MMITRGGAKAAKSLLVAAGPRLFSTVRTVSSHEALSASHILKPGVTSAWIWTRAPTIGGMRFASTITLGEKTPMKEEDANQKKTENESTGGDAAGGNNKGDKGIASYWGVEPNKITKEDGSEWKWNCFRPWETYKADITIDLKKHHVPTTFLDRIAYWTVKSLRWPTDLFFQRRYGCRAMMLETVAAVPGMVGGMLLHCKSLRRFEQSGGWIKALLEEAENERMHLMTFMEVAKPKWYERALVITVQGVFFNAYFLGYLISPKFAHRMVGYLEEEAIHSYTEFLKELDKGNIENVPAPAIAIDYWRLPADATLRDVVMVVRADEAHHRDVNHFASDIHYQGRELKEAPAPIGYH
What is the function of this protein?
Catalyzes the cyanide-resistant oxidation of ubiquinol and the reduction of molecular oxygen to water, but does not translocate protons and consequently is not linked to oxidative phosphorylation.  Increases respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures.
What are the official names of this protein?
Ubiquinol oxidase 1a, mitochondrial, Alternative oxidase 1a.
What is the protein family that this protein belongs to?
Belongs to the alternative oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein. Note=Mitochondrial, possibly in the inner surface of the inner mitochondrial membrane.
Protein: MCA3_TRYBB
Sequence: MAVDPRCLLSLCSTISKASSAKGTNDFVKIGMELWQTAQPYLVQALGLQPPPPKVDVDAAVANAGDAHGEQPWVATPLPGQTVRALFIGINYYGTSAALSGCCNDVKQMLATLQKKGLPINEAVILVDEDNFPGRTDQPTRDNIVRYMAWLVKDAKPGDVLFFHYSGHGTQCKSRGDSDEKYDQCIAPVDFQKSGCIVDDDIHKLLFSRLPEKVRLTAVFDCCHSGSIMDLPFTYVCSGGEQASGTPHMKRIREGNDVLGDVMMISGCADEQTSADVKNTATFGTGSTGAGGAATQCITCMLMNNQSLSYGKLLIETRDMLKRKRFKQVPQLSASKAIDLDQTFSLTEMFSVDRSVQ
What is the function of this protein?
Cysteine protease that cleaves specifically after arginine or lysine residues (PubMed:21949125).  In the bloodstream form, may cleave inactive metacaspase-4 MCA4 prior to MCA4 secretion (PubMed:21949125).
What are the official names of this protein?
Metacaspase-3, TbMCA3.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14B family.
What are the subcellular locations of this protein?
Recycling endosome.
Protein: GALS_SALTY
Sequence: MITIRDVARQAGVSVATVSRVLNNSALVSPDTRDAVMQAVTLLGYRPNANAQALATQVSDTIGVVVMDVSDAFFGALVKAVDLVAQQHQKYVLIGNSYHEAEKERHAIEVLIRQRCNALIVHSKALTDRELSDFMDQIPGMVLINRIVPGYAHRCVCLDNVSGARMATRMLLNNGHQRIGYLASSHRIEDDAMRREGWLHALQEQGIAASESWIGTGTPDMQGGESAMVELLGRNLQLTAVFAYNDNMAAGALTALKDNGIAIPLHLSVIGFDDIPIARYTDPQLTTVRYPIASMAKIATELALQGAAGTLDITATHCFMPTLVRRHSVAWRQNAVLITN
What is the function of this protein?
Repressor of the mgl operon.  Binds galactose and D-fucose as inducers.  GalS binds to an operator DNA sequence within its own coding sequence (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator GalS, Mgl repressor and galactose ultrainduction factor.
Protein: PYRB_LISMF
Sequence: MKNLLSMEALTVHEIEHLLEQAAQFKRGKKATFNEQTFAVNMFFEPSTRTHTSFEVAEKKLGVEVVSFDAASSSMTKGETLYDTLLTMQAVGVNVAVIRHSEENYYAGLEKLDIAIVNGGDGCGEHPSQSLLDLFTIKEQFGTFQGLKVAIAGDIRHSRVANSNMKVLKRLGAELFFSGPREWFDESYLAYGTYLSVDEIVEKVDVLMLLRVQHERHSGTDEFTKESYHEKFGLTENRAKQLKEDAIIMHPSPVNRDVEIADSLVESEKSRIVTQMTNGVFIRMAILEAILKEQEMRAKLCTY
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: TPIS_OCEIH
Sequence: MRKKVIAGNWKMNKVLSEAGEFMNSVVPKAPKGNDVEAIVCAPFPFLSKLVEQAKGSEVKVAAQNMHFEDSGAFTGEVSPVMLKDLGVTHVVLGHSERRELFAETNELVNKKTKAAFAHDLTPIVCVGETLDQREANETMNIVGEQVKQAVAGLTNEQVAETIIAYEPVWAIGTGKTATSEQANEVCTEIRKVVAEVTSADVAEKVIIQYGGSVKPANVDELLAQSDIDGALVGGASLDPESFLQLVEAGTK
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_ECOL5
Sequence: MTKKLHIKTWGCQMNEYDSSKMADLLDATHGYQLTDVAEEADVLLLNTCSIREKAQEKVFHQLGRWKLLKEKNPDLIIGVGGCVASQEGEHIRQRAHYVDIIFGPQTLHRLPEMINSVRGDRSPVVDISFPEIEKFDRLPEPRAEGPTAFVSIMEGCNKYCTYCVVPYTRGEEVSRPSDDILFEIAQLAAQGVREVNLLGQNVNAWRGENYDGTTGSFADLLRLVAAIDGIDRIRFTTSHPIEFTDDIIEVYRDTPELVSFLHLPVQSGSDRILNLMGRTHTALEYKAIIRKLRAARPDIQISSDFIVGFPGETTEDFEKTMKLIADVNFDMSYSFIFSARPGTPAADMVDDVPEEEKKQRLYILQERINQQAMAWSRRMLGTTQRILVEGTSRKSIMELSGRTENNRVVNFEGTPDMIGKFVDVEITDVYPNSLRGKVVRTEDEMGLRVAETPESVIARTRKENDLGVGYYQP
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEF_HV1EL
Sequence: MGGKWSKSSIVGWPAIRERIRRTNPAADGVGAVSRDLEKHGAITSSNTASTNADCAWLEAQEESDEVGFPVRPQVPLRPMTYKEALDLSHFLKEKGGLEGLIWSKKRQEILDLWVYNTQGIFPDWQNYTPGPGIRYPLTFGWCYELVPVDPQEVEEDTEGETNSLLHPICQHGMEDPERQVLKWRFNSRLAFEHKAREMHPEFYKN
What is the function of this protein?
Extracellular Nef protein targets CD4(+) T-lymphocytes for apoptosis by interacting with CXCR4 surface receptors.
What are the official names of this protein?
Protein Nef, 3'ORF, Negative factor, F-protein.
What is the protein family that this protein belongs to?
Belongs to the lentivirus primate group Nef protein family.
What are the subcellular locations of this protein?
Host cell membrane; Lipid-anchor; Cytoplasmic side. Virion. Secreted. Host Golgi apparatus membrane. Note=TGN localization requires PACS1. Associates with the inner plasma membrane through its N-terminal domain. Nef stimulates its own export via the release of exosomes. Incorporated in virions at a rate of about 10 molecules per virion, where it is cleaved.
Protein: RPOZ_VESOH
Sequence: MARVTVEDCLDHVENRFELVLIAAKRAHQLSSGGYKPLLNAGKDKPTVVALREIEAGLIDSSILSEIYVIDEQLSAQQKVLDSVKMSEIKDELSVTAVDKVIDEITEIEE
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: RF2_NOCFA
Sequence: MHPDVSADLAELDATLKTVESVLDIEELRRRIDELEHQAADPDLWNDQDHAQRVTSELSHAQGELRRVEDLRRRLEDLPVLYELAEGEEGEARTAALEEADAERAALHSDVEAMEVRTLLSGEYDKREALVNIRSGAGGVDAADWAEMLMRMYIRWADRHGYPVEVYDTSYAEEAGIKSATFAVKTPYAYGTLSVEMGTHRLVRISPFDNQGRRQTSFAEVEVLPVVETTDHIEVPETEIRVDVYRSSGPGGQSVNTTDSAVRITHIPTGIVVTCQNEKSQLQNKISAMRVLQAKLLERKRQEERAEMDALKTNEGASWGNQMRSYVLHPYQMVKDLRTNYEVNNPSAVLNGDIDGFIESGIRWRMRESQAS
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KUP1_BIFLO
Sequence: MGCLDVRFCRIIFALYSLIRKYGAWLVIPAMLGGAAFLADSVLTPAVSISSAVEGLKTLPALEHLFTENKDLTMMITAVIIVILFAVQSRGTESIGKVFGSVVMVWFAFLAIVGVVAIGNDWSVLAALNPYYGIKFLFSPNNATGLALMGTVFLSTTGAEALYSDMGHVGRGNIYFTWPFIKVALVLNYFGQGAWMLHNQNNPELADAEGINPFFQMMDPNVRYVAVVLSVTAGIIASQALITGAFTMVSEATGLNWMPHLQVCYPARTRGQLYIPVVNVVLCVATLAVLLLFRDSEHISAAYGLALTITMITTTILLGIYLWHRSNKFGAVVFTIVFLAIQVLFFAASMAKFLHGGWFTLLLTLAILMIMYTWNEGTKLERSQRRHMMPKDFLPALDKLHGDSRIHRFADNIVYLTSDPDLKRLDTDIFFSIFADHPKRARAWWAVAVETTDEPFTREYSVESFGTDYLFRVRIRLGFKVSQSIPAYLHQIMHDLEKTGELPNQQSIYPKLDADPGIGTIRYVVIHKALMPESKVSGRGALSLQIKYAIRRVAGSPVKWFGLAPYNPLVEVQPLFVSTRRPPRLTRVASQAPKREG
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup 1.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SCRK_FUSMR
Sequence: MIIGAVEAGGTKFVDGVGNEKGEIFER
What are the official names of this protein?
Fructokinase.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family.
Protein: SYE_ECO24
Sequence: MKIKTRFAPSPTGYLHVGGARTALYSWLFARNHGGEFVLRIEDTDLERSTPEAIEAIMDGMNWLSLEWDEGPYYQTKRFDRYNAVIDQMLEEGTAYKCYCSKERLEALREEQMAKGEKPRYDGRCRHSHEHHADDEPCVVRFANPQEGSVVFDDQIRGPIEFSNQELDDLIIRRTDGSPTYNFCVVVDDWDMEITHVIRGEDHINNTPRQINILKALKAPVPVYAHVSMINGDDGKKLSKRHGAVSVMQYRDDGYLPEALLNYLVRLGWSHGDQEIFTREEMIKYFTLNAVSKSASAFNTDKLLWLNHHYINALPPEYVATHLQWHIEQENIDTRNGPQLADLVKLLGERCKTLKEMAQSCRYFYEDFAEFDADAAKKHLRPVARQPLEVVRDKLAAITDWTAENVHHAIQATADELEVGMGKVGMPLRVAVTGAGQSPALDVTVHAIGKTRSIERINKALDFIAERENQQ
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_HAEIG
Sequence: MEQQHIEVVGKLGSTYGIRGWLRIYSSTEQAESIFDYQPWFLKIKGEWQSIELENWRYHNHEIIVKLKGVDDREAAQILANVEIGVDLSVFPELEEGDYYWHDLIGCTVVNLEGYTMGTVTEMMETGSNDVLVVKANTKDAFGKQERLIPFLYEQVVKRVDLTTKTIEVDWDAGF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_STAAN
Sequence: MTKIAFTGGGTVGHVSVNLSLIPTALSQGYEALYIGSKNGIEREMIESQLPEIKYYPISSGKLRRYISLENAKDVFKVLKGILDARKVLKKEKPDLLFSKGGFVSVPVVIAAKSLNIPTIIHESDLTPGLANKIALKFAKKIYTTFEETLNYLPKEKADFIGATIREDLKNGNAHNGYQLTGFNENKKVLLVMGGSLGSKKLNSIIRENLDALLQQYQVIHLTGKGLKDAQVKKSGYIQYEFVKEDLTDLLAITDTVISRAGSNAIYEFLTLRIPMLLVPLGLDQSRGDQIDNANHFADKGYAKTIDEEQLTAQILLQELNEMEQERTRIINNMKSYEQSYTKEALFDKMIKDALN
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.