PharMolix/UniProtQA huggingface dataset:
Protein: BNI3L_BOVIN
Sequence: MSSHLVEQPPPPHNNNNNCEEGEQSLPPPAGLNSSWVELPMNSSNGNDNGNGKNGGLEHVPSSSSIHNGDMEKILLDAQHESGQSSSRGSSHCDSPSPQEDGQIMFDVEMHTSKDHSSQSEEEVAEGEKEVDALKKSVDWVSDWSSRPENIPPKEFHFRHPKRSVSLSMRKSGAMKKGGIFSAEFLKVFIPSLFLSHVLALGLGIYIGKRLSTPSASTY
What is the function of this protein?
Induces apoptosis.  Interacts with viral and cellular anti-apoptosis proteins.  Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis.  Inhibits apoptosis induced by BNIP3.  Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates in mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria.  The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix (By similarity).  May function as a tumor suppressor (By similarity).
What are the official names of this protein?
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like.
What is the protein family that this protein belongs to?
Belongs to the NIP3 family.
What are the subcellular locations of this protein?
Nucleus envelope. Endoplasmic reticulum. Mitochondrion outer membrane. Membrane; Single-pass membrane protein. Note=Colocalizes with SPATA18 at the mitochondrion outer membrane.
Protein: PLY17_ARATH
Sequence: MTHFTVSCLLVALFLCQSLVHAAYNGYYGYSPAAAPYPAEEPQNIMNPVDSCWRLKSDWDVNREDLADCAVGFGSSTLGGKKGNIYVVTNPYDNAQNPHPGSLRYGVIQAKPLWITFAKDMVITLANELMVNSYKTIDGRGAKVEIAYGPCITIQDVTNVIVHGISIHDCKPGKSGKVRSSPTHVGHRKGSDGDAITIFGSSNVWIDHCYLASCTDGLIDVIHASTAITISNNYFTQHDKVMLLGHNDNFVKDVKMKVTVAFNHFGPGLVERMPRVRRGYAHVANNRYDKWIMYAIGGSADPTIFSEGNYFIASDKSYSKEVTKREVKGGWNNWRWRTSNDVFKNGAFFVPSGYGSIPLPYSSAQRFTVAPGNLVPSLTADAGPLNCNRNGPCY
What are the official names of this protein?
Putative pectate lyase 17.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 1 family.
Protein: CUTI_PYRBR
Sequence: MKVTALGNTLTGFGQALATTLGVDTTSSSPNCAEMMVVFARGTSEPGNVGLFSGPTFFDALEVMMGAGAVSVQGVEYGASIEGFLQGGDPAGSAAMAGIVEGTVQNCPNAKIVMSGYSQGGQLVHNAAAMLPAATMAKISSLVIFGDPNDGKPIANADPSKVMVVCHPGHNICDGRDLVLVEHLTYSRDAVEAATFAAARAKA
What is the function of this protein?
Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants (Probable) (PubMed:12795380).  Degrades cutin, a macromolecule that forms the structure of the plant cuticle (Probable) (PubMed:12795380).  Allows pathogenic fungi to penetrate through the cuticular barrier into the host plant during the initial stage of fungal infection (Probable) (PubMed:12795380).
What are the official names of this protein?
Cutinase pbc1, Cutin hydrolase.
What is the protein family that this protein belongs to?
Belongs to the cutinase family.
What are the subcellular locations of this protein?
Secreted.
Protein: H2F1_TRYB2
Sequence: MRRWLVASMAPQLHQLLQPVRRCHHPLRIPSVQLAAPRSHTHEDIAYASCPACSRVVHMCDMLTHLITAHRELDQTHCRKMCTERLALYERVIGVPLKKSELTSSGRRVLDFLPTVLPTGYMCNWCDRRSDVYATRDKFLKHVADVHTDIDLEEVEPHVPLPPRGVVVEKSNGDGGPQPTRRLNGVVAVAEKSEPINAVPRILGISLPRGVDRPLKATAQFSDTEFPCELCNRTFNSEIDLLQHLETRHPDGTAEGPAGVDSAAIADVAQFSAKEATTGGDQRVHVICDLCVSSSKVYKMPSALFSHIRFKHPNEDAAFHVERLIREQKTVSSFVCTVCQKAFASAAALDGHFNSKHAEQGEAQNVVGRVTANNCWWCHDCEKGFSSAKGLHGHMQNKHGLSSQTHPCPACKRVFADIYSLEEHLSLQHKTIRLSDIGLLTHVKCSTCERFFLSHEDLHRHAVKHHKKDPRAPAQPFEAPTSASHVAASTSAAVPSEVEATASPQGPRKVKKRKKTTEVSEVTS
What is the function of this protein?
Plays an important role in mitochondrial mRNA editing by promoting the assembly of the mRNA editosome (PubMed:26769962, PubMed:31034523).  Facilitates the recruitment of mRNA to the REH2C complex and promotes the interaction between various editing complexes including REH2C, GRBC, REMC and RECC complexes (PubMed:26769962, PubMed:31034523).
What are the official names of this protein?
REH2-associated factor 1.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ACPS_MYCTU
Sequence: MGIVGVGIDLVSIPDFAEQVDQPGTVFAETFTPGERRDASDKSSSAARHLAARWAAKEAVIKAWSGSRFAQRPVLPEDIHRDIEVVTDMWGRPRVRLTGAIAEYLADVTIHVSLTHEGDTAAAVAILEAP
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (PubMed:16709676, PubMed:21697604).  Involved in the post-translational modification of Fas-I and the AcpM subunit of Fas-II (PubMed:21697604).
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIER1_XENLA
Sequence: MAEPSLRTASPGGSAASDDHEFEPSADMLVHEFDDEQTLEEEEMLEGEVNFTSEIEHLERESEMPIDELLRLYGYGSTVPLPGEEEEDEEDMDNDCNSGCSGEIKDEAIKDSSGQEDETQSSNDDPTPSFTCRDVREVIRPRRCKYFDTNHEIEEESEDDEDYVPSEDWKKEIMVGSMFQAEIPVGICKYRETEKVYENDDQLLWDPEYVMEERVIDFLNEASRRTCEERGLDAIPEGSHIKDNEQALYELVKCNFDTEEALRRLRFNVKAAREELSVWTEEECRNFEQGLKAYGKDFHLIQANKVRTRSVGECVAFYYMWKKSERYDFFAQQTRFGKKKYNLHPGVTDYMDRLLDESESATSSRAPSPPPTTSNSNTSQSEKEDCTASNNTQNGVSVNGPCAITAYKDEAKQGVHLNGPTISSSDPSSNETDTNGYNRENVTDDSRFSHTSGKTDTNPDDTNERPIKRQRMDSPGKESTGSSEFSQEVFSHGEV
What is the function of this protein?
Transcriptional repressor regulating the expression of a number of genes.  Probably functions through recruitment of histone deacetylases involved in chromatin silencing (By similarity).
What are the official names of this protein?
Mesoderm induction early response protein 1, Early response 1, Er1, Mi-er1, Xmi-er1.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNC_BACAN
Sequence: MPYRKYREKKYETKYREAFKLFQEKIGITFTDEKLLIQAFTHSSYVNEHRKKPHEDNERLEFLGDAVLELTVSQYLFQKYPTMSEGELTKLRAAIVCEPSLVRFANELSFGSLVLLGKGEEMTGGRERPALLADVFEAFIGALYLDQGLETVWGFLKEIVYPKINEGAFSHVMDYKSQLQELIQRDGSGNIEYQILQEKGPAHNREFVSRVTLNNVALGLGSGKSKKEAEQQAAAEALKKLKEQL
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_LISMO
Sequence: MLKFDIQHFAHKKGGGSTSNGRDSESKRLGAKRADGQFVTGGSILYRQRGTKIYPGTNVGRGGDDTLFAKTDGVVRFERMGRDKKKVSVYPEVQEA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: RISB_THEMA
Sequence: MKVVQGDYRGEGLKIAVVVPRFNDLVTSKLLEGALDGLKRHGVSDENITVVRIPGSMEAIYTLKRLLDLGVHDAIIVLGAVIRGETYHFNVVANEIGKAVAQFNMTSDIPIVFGVLTTDTLEQALNRAGAKSGNKGFEAAMVAIEMANLRKRLRRDVFESDSNGR
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: APT_ACET2
Sequence: MDLKAKLREVPDFPKEGINFIDITTVLQDPEALKECIDSMKKKVESFGEFDIIVGAESRGFIFGAPLAYALGKGFVPIRKKGKLPYKTISVEYELEYGTDILEMHIDAIKKGQRVVIVDDLLATGGTTKSNIKLVEQLGGEILGIVYFVELTFLNGREKLKGYNVESIVQY
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LRFN4_MOUSE
Sequence: MAPPLLLLLLASGAAACPLPCVCQNLSESLSTLCAHRGLLFVPPNVDRRTVELRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARSFGDLESLRSLHLDGNRLVELGSSSLRGPVNLQHLILSGNQLGRIAPGAFDDFLDSLEDLDVSYNNLRQVPWAGIGSMPALHTLNLDHNLIDALPPGVFAQLSQLSRLDLTSNRLATLAPDPLFSRGRDAEASPSPLVLSFSGNPLHCNCELLWLRRLARPDDLETCASPPTLAGRYFWAVPEGEFSCEPPLIARHTQRLWVLEGQRATLRCRALGDPVPTMHWVGPDDRLVGNSSRAWAFPNGTLEIGVTGAGDAGAYTCIATNPAGEATARVELRVLALPHGGNTSAEGGRPGPSDIAASARTAAEGEGTLESEPAVQVTEVTATSGLVSWGLGRPADPVWMFQIQYNSSEDETLIYRIVPASSHHFLLKHLVPGADYDLCLLALSPAAGPSDLTATRLLGCAHFSTLPATPLCHALQAHVLGGTLTVAVGGVLVAALLVFTVALLVRGRGAGNGRLPLKLSHVQSQTNGGTSPMPKSHPPRSPPPRPQRSCSLDLGDTGGCYGYARRLGGAWARRSHSVHGGLLGAGCRGVGGSAERLEESVV
What is the function of this protein?
Promotes neurite outgrowth in hippocampal neurons.  May play a role in redistributing DLG4 to the cell periphery.
What are the official names of this protein?
Leucine-rich repeat and fibronectin type-III domain-containing protein 4.
What is the protein family that this protein belongs to?
Belongs to the LRFN family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: G1PDH_METS3
Sequence: MNTRKIQMPREVYIGPDVIYETGEICKDLHLDNKVLVLTGPNTYDIAAKHAIESLENQDIEVDVKIVEKVSYDSVEEVSEMITSGTNVLGVGGGKVIDVAKLASYDKNVFFVSMPTTASHDGIVSPLASIKNPKTSTSAKAHAPIAVIADSKIIANSPFRLLSAGCADLISNFTAIKDWQLAHRLKNESYSESAASLSIMSAKMITDNVDSIKPGLEESARLVVKTLFSSGMAISIAGSSRPASGSEHTFSHALDKILDKPCLHGEQCGVGTILMMYLYGGDWKFIRDSLKAVGAPTSAKELGISDENVIDALTMAHTIRPERYTILGDNGISEDAAYELALKTGVIK
What is the function of this protein?
Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P).  The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
What are the official names of this protein?
Glycerol-1-phosphate dehydrogenase [NAD(P)+], G1P dehydrogenase, G1PDH, Enantiomeric glycerophosphate synthase, sn-glycerol-1-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glycerol-1-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARP4A_ARATH
Sequence: MYGGDEVSAIVVDLGSHTCKAGYAGEDAPKAVFPSVVGAIDGNGMDIDDAANTTEDAKESDKEKGKRKLYTGSQALNFRRDQMEILSPTKDGIVTDWDMVDNVWDHAFRNCLMIDPTEHPMLLAEPPLNSQQQREKSGFSTFYRC
What are the official names of this protein?
Actin-related protein 4A, Actin-related protein 5.
What is the protein family that this protein belongs to?
Belongs to the actin family. ARP4 subfamily.
Protein: XOAT6_ORYSJ
Sequence: MQQRRKSVFASAPFAMKQAALGAGVAARRNGAPLSLAAVVFALFVFATFLYNEDIKSIADFPFGAGALRAKSPDLHVLQETVGAAHLAAGSIAKRGEEVIVRVLDAPASTAMAAAAGSSSNNSTIEVAKANANANANAADAGVKVDEGQERERDVTLPSVKEGGADEARRREDEEAAEKESSAKAAAATAALRTVVSVPDTCDLYRGNWVYDEVNAPVYKESQCEFLTEQVTCMRNGRRDDSYQKWRWQPTDCDLPRFDARLLLERLRNKRLMFVGDSLNRNQWESMVCLVQSVIPKGKKTLTKFVNGGNSNIFYAHEYNATVEFYWAPFLVESNSDNPQVHSVPDRVIQWHSIAKHAHNWLGVDYLIFNTYIWWLNTLDMKVLKGSFDQGATEYVEVDRPVAYKEVLKTWAKWVDRNIDPNRTTVFFMSMSPNHITPEAWGNYGGIKCAMETLPITNRTTSLDVGTDWRLYAGAQEVLQTFRRVPVHLVDITALSELRKDAHTSVHTLRQGKLLTPEQQSDPKTYADCIHWCLPGLPDTWNQFLYARIASAPWSSDQ
What is the function of this protein?
Xylan acetyltransferase required for 2-O- and 3-O-monoacetylation of xylosyl residues in xylan (PubMed:29569182).  Catalyzes the 2-O-acetylation of xylan, followed by nonenzymatic acetyl migration to the O-3 position, resulting in products that are monoacetylated at both O-2 and O-3 positions (By similarity).
What are the official names of this protein?
Xylan O-acetyltransferase 6, Protein trichome birefringence-like 15, OsTBL15.
What is the protein family that this protein belongs to?
Belongs to the PC-esterase family. TBL subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: ENGB_NITMU
Sequence: MSVFQNATFYTTVNELRDLPPPVGVEIAFAGRSNAGKSSAINTLANRNRLAFVSKTPGRTQHLNFFRLGNDRFLVDLPGYGYAKVPAEVRQHWERLLGTYLQTRQSLHGMVLIMDARHPLTPLDRQMLAWFAPTKKAVHVLLTKSDKLTRQQGQKVLKTVLGFLRESYPQCSVQLFSSTSREGVKEAAALLDAWFGSGIEPDSGMIREAGAPESGKGNAPEPPNARNKKPPVKGE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: VAX1_HUMAN
Sequence: MFGKPDKMDVRCHSDAEAARVSKNAHKESRESKGAEGNLPAAFLKEPQGAFSASGAAEDCNKSKSNSAADPDYCRRILVRDAKGSIREIILPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQGKDSELRSVVSETAATCSVLRLLEQGRLLSPPGLPALLPPCATGALGSALRGPSLPALGAGAAAGSAAAAAAAAPGPAGAASPHPPAVGGAPGPGPAGPGGLHAGAPAAGHSLFSLPVPSLLGSVASRLSSAPLTMAGSLAGNLQELSARYLSSSAFEPYSRTNNKEGAEKKALD
What is the function of this protein?
Transcription factor that may function in dorsoventral specification of the forebrain.  Required for axon guidance and major tract formation in the developing forebrain.  May contribute to the differentiation of the neuroretina, pigmented epithelium and optic stalk (By similarity).
What are the official names of this protein?
Ventral anterior homeobox 1.
What is the protein family that this protein belongs to?
Belongs to the EMX homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ZD20A_DANRE
Sequence: MAPSHAVRCCQRGLSWIPVIFINLVVCWSYYAYVVELCIYTIPNVNEQVIYLVVFHAFFFMFMWSYWKTISSKPTNPSKEFCLPKAEKELYEKEERPEAQQDILKRVARELPIYTFTGSGAIRYCDRCQLIKPDRCHHCSTCDKCVLKMDHHCPWVNNCVGFSNYKFFVLFLAYSMLYCVYIAATVLQYFIKFWTNQLPDTHAKFHVLFLFFVAAMFFISILSLFSYHLWLVGKNRTTIEAFRAPVFRNGPDKNGFTLGFRKNITQVFGDQKKYWCLPIFSSLGDGYTFPTRLVTVDVEHGNIEHQTIKCTVDGQTNARPLSESQNHLLCNDEGQKDSSMAAIEVCQPVCVTLENES
What is the function of this protein?
Palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates.  Catalyzes palmitoylation of Cys residues on protein substrates and has a preference for acyl-CoA with C16 fatty acid chains but may also utilize acyl-CoA with C14 and C18 fatty acid chains.
What are the official names of this protein?
Palmitoyltransferase ZDHHC20-A, Acyltransferase ZDHHC20-A, Zinc finger DHHC domain-containing protein 20-A.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasm, perinuclear region. Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein.
Protein: MTXH_METAC
Sequence: MFKFQKEQEIANIAGIKVGGQPGELPTLLAGTIFYNKHEIVEDAAKGLFDRIAAEKLVNLQEVGSDMTGNPHMVHIFGTTQESITRYIDFIAEVSESPFLIDSPEGTVRAHASRYVSEIGLADRAVYNSINMSITTSEIEALAQSDIDSSIILGFNAMDSSLRGRMEMLETGAGLLEEGLLSIADRCGIVNKLIDPSITPMGNGAGIALRMTITAKAKWGYPTGSGIHNAPSAWNWLNRQKEKNPVLYKICDVGSTCLQQAAAGDFILYGPIEYAQYVFPMAAMSDIMIAEAVADLDIEPASRHPINLLV
What are the official names of this protein?
Putative methyltransferase mtx subunit H.
What is the protein family that this protein belongs to?
Belongs to the MtrH family.
Protein: ATRA_EMENI
Sequence: MGVPDELPPGSSETDTIVSSSQPTNRSPMDLISEAESLNLRRIATNQSKAQCRPGSAAVPSHDNPPNDDLEDATLDPNSASFSLEKWLRAAVSDASQHGLSTPSGGILFRNLTVSGSGSALQLQPTVGSVLTAPLRFASLLRHRRIEPRRILHGFDGVMKTGELLLVLGRPGAGCSTFLKTVCGETNGLHIDADSVLHYNGVSQQRMMKEFKGEVVYNQEVDKHFPHLTVRQTLEFAAAARTPAHRFQNMSRDEFASYAASVVMAIFGLSHTHNTKVGNDFVRGVSGGERKRVSIAEMALAMTPFAAWDNSSRGLDSATALKFVQALRLSADLAGAAHAVAIYQASQSIYEVFDKVTVLYEGRMIFFGPTGTAKEYFERMGWVCPARQTTGDFLTSITNPLERKARAGMEDVVPKTPKDFEIYWRQSPEYKTLLGEMTEFETQHPTGNDEQASAELRARKENSQSRNSRAASPYILSIPMQIKLNTKRAYQRIWNDMSSTMSTVVGQIVIALITGSVFYDSPNTTAGFQSKGGTLFYAVLLNALTAMSEITSLYSQRPIVEKQASYAFYHPATEAIAGVVSDVPVKFLLAVAFNVIMYFLANLRREPAQFFIYFLMSFTVMFVMSAVFRTMAAVTKNAAQAMGLAGVLMLALVVYTGYVLPVPSMHPWFEWIHYLNPIYYAFEAMIANEFHGRDFDCIAFVPSYADLDGDSFSCSSLGSVAGERMVSGDSYINFNYTYTYSHVWRNFGVLLAFLIGFMAIYFLASELNSSTTSTAEALVFRRGHVPEYMRPGYTRPTDEEKAVTQSDIKPSSPSPTNTDLPLPPQRDIFTWKDISYDIEIKGEPRRLLDDVSGWVKPGTLTALMGVSGAGKTTLLDVLAHRTTMGVITGDMFVNGKGLDASFQRKTGYVQQQDLHLETATVRESLRFSALLRQPASVSIREKHDYVESVIEMLGMGDFAEAVVGTPGEGLNVEQRKLLTIGVELAAKPKLLLFLDEPTSGLDSQSSWAICTFLRKLADSGQAVLCTIHQPSAILFQEFDQLLFLAKGGKTVYFGPIGPNSRTLLDYFESNGARKCDEAENPAEYMIEVVNAEVNDRGTDWFDVWKGSKECQAVKEEIERIHEKKRGTAGAIEETDDGSTKSEFAMPFWFQLYVVTVRVFQQYWRMPEYIISKGALAIVAGLFIGFSFYDAKTSLAGLQTLVFSLFMVCALFAPLVNQIMPLFITQRSLYEVRERPSKAYSWKAFLIANILVEIPYQVLMGILTFVCYYYPVVGSSQGPDREGLVLLFCIQFYVYASTFAHMCIAAMPNAETASPIVILLFSMCLTFCGVMQPPDALPGFWIFMYRVSPFTYWVAGMATTQVHGREVVCGENELSIFDPPTNQTCGQYMERYISVAGGQVLNPSATAGCEYCSLTVADEYLAASQIYWSDRWRNFGLIWVYIGFNIFVATAVYYLFRVKKWNGRRKK
What is the function of this protein?
Pleiotropic ABC efflux transporter involved in the basal level of drugs susceptibility, including antibiotics, azole fungicides and plant defense toxins.
What are the official names of this protein?
ABC multidrug transporter atrA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AROC_BUCBP
Sequence: MAGNSIGKLFRVTTFGESHGPKLGCIIDGTPPGLEISENDFQKELDRRRPGTSKYTTQRRELDKITILSGIFQGKTTGTSIGLTVKNTDQRSQDYNNIQKLFRPGHADFTYYKKYGIRDPRGGGRSSARETVMRVAAGAIAKKYLYTKYGILIRGYLKQIGNITCKLKSWNEVEKNPFFCPDVKQINNLNLLIKKLKKEGDSIGAKIKIIAEKVPIGLGEPVFDRLDADLAHSLMSINAVKGVEIGDGFAVVNQKGSEHRDEMNKHGFTNNHAGGILGGISNGENIIATIALKPTSSIKKIGKTIDLHGREQKISILGRHDPCVGLRAVPIAEAMMSITIMDHILRHRGQCSKTY
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: 3HAO_XANAC
Sequence: MLTPPINLHAWIEEHRHLLKPPVGNKCIQQDGFIIMVVGGPNARTDYHYDEGPEWFFQLEGEMVLKVQDEGVARDIPIRAGEVFLLPPKVPHSPQRADGSIGLVIERERLPTEQDGLQWYCPQCNHKLYEAMFPLKNIETDFPPVFDRFYRSPALRTCSQCGHLHPAPERYATVEG
What is the function of this protein?
Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
What are the official names of this protein?
3-hydroxyanthranilate 3,4-dioxygenase, 3-hydroxyanthranilate oxygenase, 3-HAO, 3-hydroxyanthranilic acid dioxygenase, HAD.
What is the protein family that this protein belongs to?
Belongs to the 3-HAO family.
Protein: FADI_SHEPC
Sequence: MSDRQQVTNAKGERIAIVAGLRTPFAKQATAFHGVSALDMGKMVVNELLVRSELDPKLIEQLVYGQVVQMPAAPNIAREIVLGTGMNVSTDAYSVTRACATSFQSTVNVAESIMTGNIDIGIAGGADSSSVLPIGVSKKLAHALVDLNKARSFGQKLQIFRRLGLKDLLPVPPAVAEYSTGLSMGQTAEQMAKTYNISRADQDALAHRSHTLASETWASGHLRDEVMVAHIPPYKQFIDRDNNIRENSVLESYAKLRPAFDKQHGTVTAANSTPLTDGASAIILMSEGRAKALGYQPIGYIKSYAFSAINVWQDMLMGPSYATPLALKRAGMELEDLTLIEMHEAFAAQTLANMQMFASKKFAEEKLGRNRAIGEIDMSKFNVLGGSLAYGHPFAATGTRLITQVCRELKRRGGGTGLTTACAAGGLGVAMIVEVE
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, ACSs, Acetyl-CoA acyltransferase, Acyl-CoA ligase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COABC_METJA
Sequence: MISEIMHPTKLLKGTKSKLLENKKILVAVTSSIAAIETPKLMRELIRHGAEVYCIITEETKKIIGKEALKFGCGNEVYEEITGDIEHILLYNECDCLLIYPATANIISKINLGIADNIVNTTALMFFGNKPIFIVPAMHENMFNAIKRHIDKLKEKDKIYIISPKFEEGKAKVANIEDVVKAVIEKIGNNLKKEGNRVLILNGGTVEFIDKVRVISNLSSGKMGVALAEAFCKEGFYVEVITAMGLEPPYYIKNHKVLTAKEMLNKAIELAKDFDIIISSAAISDFTVESFEGKLSSEEELILKLKRNPKVLEELRRIYKDKVIIGFKAEYNLDEKELINRAKERLNKYNLNMIIANDLSKHYFGDDYIEVYIITKYEVEKISGSKKEISERIVEKVKKLVKS
What is the function of this protein?
Catalyzes two sequential steps in the biosynthesis of coenzyme A.  In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine.  In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
What are the official names of this protein?
Coenzyme A biosynthesis bifunctional protein CoaBC, DNA/pantothenate metabolism flavoprotein, Phosphopantothenoylcysteine synthetase/decarboxylase, PPCS-PPCDC.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PPC synthetase family.
Protein: FABH_STAAS
Sequence: MNVGIKGFGAYAPEKIIDNAYFEQFLDTSDEWISKMTGIKERHWADDDQDTSDLAYEASLKAIADAGIQPEDIDMIIVATATGDMPFPTVANMLQERLGTGKVASMDQLAACSGFMYSMITAKQYVQSGDYHNILVVGADKLSKITDLTDRSTAVLFGDGAGAVIIGEVSDGRGIISYEMGSDGTGGKHLYLDKDTGKLKMNGREVFKFAVRIMGDASTRVVEKANLTSDDIDLFIPHQANIRIMESARERLGISKDKMSVSVNKYGNTSAASIPLSIDQELKNGKIKDDDTIVLVGFGGGLTWGAMTIKWGK
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.