PharMolix/UniProtQA huggingface dataset:
Protein: CEMA_AETGR
Sequence: MAKKKAFIPFLYFISIVFFPWWISLCCNKSLKTWITNWWNTRQCETFLNEIQEKSLLEKFIQLEELFQLDEMLKEYPETDLQKFRLEIHKETIQFIKIHNEYRIHTIFHFSTNLISFVILSSYSFWGKEKLFILNSWVQEFLYNLSDTIKAFLILLLTDLCIGFHSPHGWELMIGYIYKDFGFAHYEQILSGLVSTFPVILDTIFKYWIFRYLNRVSPSLVVIYHAIND
What is the function of this protein?
May be involved in proton extrusion.  Indirectly promotes efficient inorganic carbon uptake into chloroplasts.
What are the official names of this protein?
Chloroplast envelope membrane protein.
What is the protein family that this protein belongs to?
Belongs to the Cema family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: FIGLA_HUMAN
Sequence: MDPAPGVLDPRAAPPALLGTPQAEVLEDVLREQFGPLPQLAAVCRLKRLPSGGYSSTENLQLVLERRRVANAKERERIKNLNRGFARLKALVPFLPQSRKPSKVDILKGATEYIQVLSDLLEGAKDSKKQDPDEQSYSNNSSESHTSSARQLSRNITQHISCAFGLKNEEEGPWADGGSGEPAHACRHSVMSTTEIISPTRSLDRFPEVELLSHRLPQV
What is the function of this protein?
Germline specific transcription factor implicated in postnatal oocyte-specific gene expression.  Plays a key regulatory role in the expression of multiple oocyte-specific genes, including those that initiate folliculogenesis and those that encode the zona pellucida (ZP1, ZP2 and ZP3) required for fertilization and early embryonic survival.  Essential for oocytes to survive and form primordial follicles.  The persistence of FIGLA in adult females suggests that it may regulate additional pathways that are essential for normal ovarian development.  Binds to the E-box (5'-CANNTG-3') of the ZPs (ZP1, ZP2, ZP3) promoters.
What are the official names of this protein?
Factor in the germline alpha, FIGalpha, Class C basic helix-loop-helix protein 8, bHLHc8, Folliculogenesis-specific basic helix-loop-helix protein, Transcription factor FIGa.
What are the subcellular locations of this protein?
Nucleus.
Protein: DCUP_LISMO
Sequence: MTKITNDLFLKAARKEQVDRIPVWYMRQAGRSQPEYRKLKEKYSLFEITHQPEICAYVTKLPVDQYGVDAAILYKDIMTPLPGMGVDVEIKSGIGPVIHNPIRSFQDVEKLTIFKPEIEVPYVLDTIKLLADDMLDVPLIGFAGAPFTLASYMIEGGPSKNYHQTKSFMYREPEVWAILMEKLGRMTANYLIAQINAGASAVQLFDSWVGALSRADYAEYIRPVIEMIVREVKAVHPTTPIIMQAVGASHLLEEWETMPLDVVGVDWRETITSARKKVPTKAIQGNLDPSTLLAPEKCLKEANRILQEGVLEPGYIFNLGHGVFPEVPPEMLKQLTNYIHERSEILLKKDDIK
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YGHD_ECOLI
Sequence: MLRDKFIHYFQQWRERQLSRGEHWLAQHLAGRSPREKGMLLAAVVFLFSVGYYVLIWQPLSERIEQQETILQQLVAMNTRLKNAAPDIIAARKSATTTPAQVSRVISDSASAHSVVIRRIADRGENIQVWIEPVVFNDLLKWLNALDEKYALRVTQIDVSAAEKPGMVNVQRLEFGRG
What is the function of this protein?
Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of folded proteins across the outer membrane.
What are the official names of this protein?
Putative type II secretion system M-type protein YghD, Putative T2SS M-type protein YghD, Putative extracytoplasmic function protein C, Putative general secretion pathway M-type protein YghD.
What is the protein family that this protein belongs to?
Belongs to the GSP M family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: Y554_ARCFU
Sequence: MITMSRRAESRQIEANEVLDIRGEVCPFTFIETKLKLEEMKSGEILRVIIDHEPAVRDVPRSVEQEGHEVLSVEKVGEKEWSILIKKK
What are the official names of this protein?
Putative sulfur carrier protein AF_0554.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
Protein: TCTP_MEDSA
Sequence: MLVYQDLLTGDELLSDSYPYKEIENGMLWEVEGKWVTKGVVEVDIGANASAEGGEDEGVDDTAVKVVDIVDVFRLQEQPAFDKKQFLGFVKRYIKLLTPKLDAEKQELFKKHIEGATKYLLCKLKDLQFFVGESMHDDGSLVFAYYKDGAADPTFLYFAYALKEIKC
What is the function of this protein?
Involved in calcium binding and microtubule stabilization.
What are the official names of this protein?
Translationally-controlled tumor protein homolog, TCTP.
What is the protein family that this protein belongs to?
Belongs to the TCTP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2997_BORBR
Sequence: MRRPVPYHRVAAIMTILSLAGAGHQARLDARGGMLTGPTANLAPGHVQANLAILPQAVAGDFLRFCQRNPKPCPLLAVSEPGDPSLPELGLDIDIRTDVPRYRVWRDGKLVDEPLDVRGLWRDDLVAFLIGCSFSFEEAMLENGLPVRHIEQGCNVPMYRTNIATHPAGPFSGPLVVSMRPLKAADAIRAIQVTSRFPSVHGAPVHLGDPALIGIADLGRPDYGDAVEIRAGEIPVFWACGVTPQSVVAAVRPEFCITHAPGHMLVTDLLNSRLAAF
What are the official names of this protein?
Putative hydro-lyase BB2997.
What is the protein family that this protein belongs to?
Belongs to the D-glutamate cyclase family.
Protein: RLMF_PSEMY
Sequence: MPQPPKRPRKPAPAAVKTAPAKGELHPRNRHQGRYDFPALIKVSPELGDFVITNPYGKPSIDFANPAAVKVFNRALLAQYYGIRHWDIPDGYLCPPIPGRADYLHNLADLLATDNDGQIPRGAGIHALDIGVGANCIYPLIGHCEYGWHFIGADIAPAALASARAIVAANPQLAGGIELRQQANAEQIFLGLLQADERVDLTLCNPPFHASADEATRGSTRKWRNLGKLDPRRKLPVLNFGGQAAELWCPGGEAAFLKRMASESAQVAGQVLWFSSLVSKGSNVELLQGWLAKAGAAEVRILGMSQGQKQSRLVAWTFKDGEARGAWRQSRWR
What is the function of this protein?
Specifically methylates the adenine in position 1618 of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase F, 23S rRNA mA1618 methyltransferase, rRNA adenine N-6-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL16/RlmF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_CAUVC
Sequence: MAKLHFSLVAPERELFSGEVDMVQAPGAEGDFGVLANHAPFMTTLREGKVTVKDGATTKVFDIQGGFADVGPEGLTILAEHAVEAA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RECR_PROM3
Sequence: MIDQFERLPGIGPRTAQRLALHLLRQPEDQIRAFAEALLAARSQVGQCQTCFHLSAEPLCDICRDGTRCDQLLCVVADSRDLLALERTREYKGRYHVLGGLISPMDGIGPDMLQIPSLIQRVDRDGISEVILALTPSVEGDTTSLYLARLLKPFTQVSRIAYGLPVGSELEYADEVTLTRALEGRRAMQ
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: H2A7_WHEAT
Sequence: MAGRGKAIGSGAAKKAISRSSKAGLQFPVGRIARFLKAGKYAERVGAGAPVYLAAVLEYLAAEVLELAGNAARDNKKTRIVPRHIQLAVRNDEELSRLLGMVTIASGGVMPNIHNLLLPKKAGGSKAVAADDDS
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Protein H2A.7, wcH2A-10, wcH2A-4.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: TAFA4_MACFA
Sequence: MRSPRMRACAKSVLLSHWVFLAYVLMVCCKLMSASSQHLRGHAGHHQIKQGTCEVVAVHRCCNKNRIEERSQTVKCSCFPGQVAGTTRAQPSCVEASIVIQKWWCHMNPCLEGEDCKVLPDYSGWSCSSGNKVKTTKVTR
What is the function of this protein?
Modulates injury-induced and chemical pain hypersensitivity.  Ligand of FPR1, can chemoattract macrophages, promote phagocytosis and increase ROS release.
What are the official names of this protein?
Chemokine-like protein TAFA-4.
What is the protein family that this protein belongs to?
Belongs to the TAFA family.
What are the subcellular locations of this protein?
Secreted.
Protein: YE087_YEAST
Sequence: MVLFILVLYTCIQDGNGLLCGYISFSNTPMTSAKCWIGTVCFSIPCSFLVHFHCSSLHLFSNCFLHRSFSPHLMPRTSISTLGQLFEPTITHNGIPMACDNFILAPIPSFSLNWSRMSFCKFCMVGSFSSSDLTSCNLCEFSGLFGPVQIDTLYGAIIAGHLNPLESRPSSAIAPTSLLTPMP
What are the official names of this protein?
Putative uncharacterized protein YER087C-A.
Protein: UVRA_THEMA
Sequence: MNEIVVKGARVHNLKNITVRIPKNRLVVITGVSGSGKSSLAMDTIYAEGQRRYLESLSTYARQFLGNLKKPDVDEIEGLSPAIAIDQKTVSHNPRSTVGTVTEIYDYLRVLYARIGKAHCPECGRPLEKKSIDEILQDLFNSFKEGSRIYILAPVATEKKGTFKKEIEEFISKGFARIEIDGEIYRLEEVPELDKNKRHTVKLVVDRLILETRNEHRILDSLELAMREGKGFVEIRNVDTGESKIFSENLMCPVCGIGFPEITPKLFSFNSPYGACPNCHGLGFTFEVDPSLVIDEEKSVLEGAIIPYRWDRRLSRWVAREIEKRGVSPHLPFKDLPEDVKEFILYGDDRFEGVVPKVQRWHRETESPEMKEWLEKNFIVQRTCSVCGGRRLNREALSVKINGLNIHEFTELSISEELEFLKNLNLTEREREIVGELLKEIEKRLEFLVDVGLEYLTLSRSATTLSGGESQRIRLATQIGSGLTGVIYVLDEPTIGLHPRDTERLIKTLKKLRDLGNTVIVVEHDEEVIRNADHIIDIGPGGGTNGGRVVFQGTVDELLKNPDSSLTGEYLSGKRKITVNKTRRLPYASLKIKGVRHNNLKNIDVEIPLGVFVCVTGVSGSGKSSLVMETLYPALMNLLHKTKLPAGEFDSIEGHENIDKMIAIDQSPIGRTPRSNPATYTKVFDEIRSLFAMTPAAKARGYNKSRFSFNLKGGRCEACQGQGYVKIEMLFLPDVYVECDVCKGKRYNRETLEITYKGKNISDILDMTVDEALEFFKNIPSIKRTLQVLHDVGLGYVKLGQPATTLSGGEAQRIKLASELRKRDTGRTLYILDEPTVGLHFEDVRKLVEVLHRLVDRGNTVIVIEHNLDVIKNADHIIDLGPEGGKEGGYIVATGTPEEIAKNPHSYTGRFLKNVL
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrA is an ATPase and a DNA-binding protein.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
What are the official names of this protein?
UvrABC system protein A, UvrA protein, Excinuclease ABC subunit A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. UvrA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_SULIY
Sequence: MGDPKKSRKKWESPGHPWIKERIGYEQELLGKYGLRNKREIWIAQSIIRKFRHQARSLLALPPAERAVREKQLVGKLLKMGLLKRETATVDDILSLTEQDLLERRLQTIVYKKGLANTTYQARQLIIHGHIAVNGKRVTSPGYIVNVDEENLIDYYVTSSFKSRPPVMAQQEGGEAGVKQA
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: ACT3_DICDI
Sequence: MESEDVQALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRYTGVMVGMGQKDSYIGDEAQSRKGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVSHTVPIYEGYSLPHAILRLDLAGRDLTDYMMKILTERGYSFTTTAEREIVRDIKEKLAYVALDFEAELQTAASSSALEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESAGIHETTYNSIMKCDVDIRKDLYSNVVLSGGSTMFPGIADRMNKELTALAPSTMKIKIIAPPERKYSVWIGGSILASLPTFQQMWISKEEYDESGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.  Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction.
What are the official names of this protein?
Actin-3, Actin-3-sub 1.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: U512X_DICDI
Sequence: MTLFNSISSISNSTGISKESLIGNLNSNGIATGNISVSWLGGFDGCGGCGGGCGKNDFLYSSL
What are the official names of this protein?
UPF0512 protein X.
What is the protein family that this protein belongs to?
Belongs to the UPF0512 family.
Protein: UREE_METPP
Sequence: MLTLNKLLARGAGLAPALLKRAATVELDWDVRQKSRFDATDSQGRALGVFLPRGSVVRGGDVLVAEDGSLVRVIAAPQSVLVVRHCSEHGSAFDLLRAAYHLGNRHVPLELQPDRLQLEPDHVLADMLRAMHLIVSEAQAPFEPESGAYGEAAAHGHGHAGHDHAHDHDHGPAQASTPAPTPRGRPVGVAIKAAAPAPHVHGPGCGHDHDHGSGHHH
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YI48_SCHPO
Sequence: MNFFLYFRTIFLIQLYFFNYSTFGCSASSTSVQSDTTNQVSVSCPKYTTIYTSGTSPDTKTIYPESTSTKSITTSTQSHSSPVIVVSTVGTVTETTISGSTEYTTTIPAEGITSGTVEIVEPTAGTVTETITSGTLPFTTTLAQASGTVSGTVEIVSPKNNPTTVYSGTVATTETFSSSTVVVIPTAICDGVRGLEYAVYDYTISSSMNEFCYPKNGQTDVFAFNEPAYFGSSDLDQSSPLFTGVFSSTDDIPEWASSWYLPPYPPQASDMASTYCACKVIVYQFFLRIPETDTYTLVVNNVDDVFFGWFGDKAISGWSNNNFDAYSYWHESPNMGLGTVGMGNFTVGNYPEGYFLPVRFVVANGAYIGGFDFYFTSDSTGPLATTSYSYTKTCTQQFLPFGQGNGGVNGPTEKLS
What is the function of this protein?
May be involved in agglutination during conjugation or other aspects of colony formation.
What are the official names of this protein?
Putative cell agglutination protein SPAC1348.08c, Adhesin SPAC1348.08c.
What are the subcellular locations of this protein?
Cell surface.
Protein: MUS81_ORYSJ
Sequence: MAPEARQLKVHLRENEAVAQCVLEKWRSMEEKPGGLKENLAHTLYKSYRNVCAAKEPIRSLKDLYQIKGVGKWVIRQLKGSFPESSPDLSPPESNAAGEKGKKAGGSKRYVPQKNSAAYAILITLHRETINGKSHMKKQELIDATEASGLSRSAIGPDKSKAKPGAFASSQKDWYTGWSCMKTLTSKGLVAKSGNPAKYMITEEGKSTALECLSRSGLDDHAAPLVINSAPDTSNASHKLNNICMTSFVETSSGPSRAIGRPKTSIANPATKTSPEVTYLTSQESLNYNSDVRTAENCAEEIILSDSDSEELYTENYPLIGSEEFTERVAPPILNASNSGKTTTNYRFSDCSASISPRSSEGTFEMQSSSTMGIAEFNMLDNDTVCMDNSILAMPPRRSSKNFLEDYEVVLILDDRENFGGRSRKTVDNIHSQFRVPVEIKHLPVGDGIWIARDRKLHTEYVLDFIVERKNVADLCSSITDNRYKDQKLRLKKCGLRKLIYLVEGDPNPLDTSERIKTACFTTEILEGFDVQRTPGYAETVRTYGNLTHSITEYYSTHFSTGANTSQVCLTYDEFTKKCDDLKKITVSDVFALQLMQVPQVTEEAALAVIGLYPTLFSLAKAYSMLDGDTHAQEKMLKNKSTLINAGASRNIFKLVWAEG
What is the function of this protein?
Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick.  Typical substrates include 3'-flap structures, D-loops, replication forks, nicked Holliday junctions and also intact Holliday junctions with a reduced efficiency.  May be required in mitosis for the processing of stalled or collapsed replication fork intermediates.  Plays a role in DNA repair and in genotoxic stress-induced homologous recombination (HR) in somatic cells.  Mediates a subset of meiotic recombination events that are insensitive to crossover interference (By similarity).
What are the official names of this protein?
Crossover junction endonuclease MUS81, Protein MMS AND UV SENSITIVE 81, OsMUS81.
What is the protein family that this protein belongs to?
Belongs to the XPF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CPSB_STRA5
Sequence: MIDIHSHIVFDVDDGPKTLEESLSLIEESYRQGVRIIVSTSHRRKGMFETPEDIIFKNFSIVKHEAEKRFEHLQILYGGELYYTSDMLEKLKLKQIPTLNNTKFALIEFSMQTSWKDIHTALSNVLMLGITPVVAHIERYNALENQKERVKEIINMGCYTQINSSHILKQKLFNDKHKRFKKRARYFLEENLVHFVASDMHNLDVRPPFLAEAYKIICRDFGKERANQLFIENAQSILKNHYI
What is the function of this protein?
Dephosphorylates CpsD.  Involved in the regulation of capsular polysaccharide biosynthesis (By similarity).
What are the official names of this protein?
Tyrosine-protein phosphatase CpsB.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.
Protein: NUOB_HELAH
Sequence: MQQAPVVLSTLDKLLNWGRSNSLWPLTYGLACCAIEMMATGGSRFDFDRFGTIFRASPRQSDVMIIAGTLTKKHAEFMRRLYDQMPEPKWVISMGSCANTGGMFNTYATVQGADRIIPVDIYLPGCAPRPETLQYALMVLQDKIRRSKAIKQDAPKRLV
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HEM1_DESAL
Sequence: MDIVLVGLNHKTAPVDIRECFAFDSLEADAGLKELSRIPELTEAVLISTCNRVEIAAACQDPDEGIAAIKDFFSRTKSMPLENFEQNLFVYKGDEAVQHVFRVASSLDSMVLGEPQILGQMKESYRLATQAKTTGAVLNRLMHRCFMTAKRVRKETGIGDHAVSISYAAVELARKIFGELTDKKVLLIGAGEMAELAVEHLLNHRAAGVFVANRTFERAVALAERFRGTPIRLEEVEEHLKIADIIISSTGAPGYVLEKKDVKKVLRARKNRPLFFIDIAVPRDIDPAINNLSNNFVYDIDDLQGVIDRNIDERQKEAVRAERIVDENVIKYRTWLEGLDIVPTIVSLQKKLEAIRQAEMAKSLANIPEIDEKGREAIERLTQSIINKVMHDPIQFLKAGGHREKQKKEVLGFTRDIFNLNNPQNGDEFTPDEE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: XKS1_ASPFU
Sequence: MTSQGPLYIGFDLSTQQLKGLVVNSELKVVHISKFDFDADSHGFSIKKGVLTNEAEHEVFAPVALWLQALDGVLNGLRKQGLDFSRVKGISGAGQQHGSVYWGENAESLLKSLDSSKSLEEQLSGAFSHPFSPNWQDASTQKECDEFDAFLGGPEQLAEATGSKAHHRFTGPQILRMQRKYPEVYKKTARISLVSSFLASLLLGHIAPMDISDVCGMNLWDIKKGAYNEKLLGLCAGPFGVEDLKRKLGAVPEDGGLRLGKINRYFVERYGFSSDCEILPSTGDNPATILALPLRPSDAMVSLGTSTTFLMSTPNYKPDPATHFFNHPTTPGLYMFMLCYKNGGLAREHVRDAINEKSGSGASQSWESFDKIMLETPPMGQKTESGPMKMGLFFPRPEIVPNVRSGQWRFTYDPASDALTETEDGWNTPSDEARAIVESQMLSLRLRSRGLTQSPGDGLPPQPRRVYLVGGGSKNKAIAKVAGEILGGSDGVYKLDVGDNACALGAAYKAVWAIERKPGQTFEDLIGQRWREEEFIEKIADGYQKGVFEKYGKAVEGFEKMEQQVLKQEAARK
What is the function of this protein?
Highly specific D-xylulose kinase which participates in the catabolism of xylose.  Xylose is a major component of hemicelluloses such as xylan.  Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway (By similarity).
What are the official names of this protein?
Probable D-xylulose kinase A, Xylulokinase A.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RTP3_MOUSE
Sequence: MMEEDIGDTEQWRHVFQELMQEVKPWHKWTLIPDKNLLPNVLKPGWTQYQQKTFARFHCPSCSRSWASGRVLIVFHMRWCEKKAKGWVKMRVFAQRCNQCPEPPFATPEVTWDNISRILNNLLFQILKKCYKEGFKQMGEIPLLGNTSLEGPHDSSNCEACLLGFCAQNDLGQASKPPAPPLSPTSSKSAREPKVTVTCSNISSSRPSSKVQMPQASKVNPQASNPTKNDPKVSCTSKPPAPPLSPTSLKSAREPKVTVTCSNISSSRPSSKVQMPQASKVNPQTSNPTKNDPKISCTSKPSTTPRLTIQQLSVVSPPAPAPTCVIQMPSPTPIDGSRAADVAKENTRSKTPKALLSSPLYVPPTSSYVPPTSSYVPPTSSYVPPTSSYVPPTSSSVIVPISSSWRLPENTICQVERNSHIHPQSQSSCCGACCESWCEIFRYSCCEAACNCMSQSPLCCLAFLILFLLLWYLL
What is the function of this protein?
Promotes functional cell surface expression of the bitter taste receptors TAS2R16 and TAS2R43.
What are the official names of this protein?
Receptor-transporting protein 3, Transmembrane protein 7.
What is the protein family that this protein belongs to?
Belongs to the TMEM7 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type III membrane protein.
Protein: GLCM1_CAPHI
Sequence: MKFLCILLLASLAATSLAILNEPEDETHLEAQPTDASAQFIISNLQISTEDLSKEPSISREDLISKEPNVIRSPRQPQNQNPKLPLSILKEKQLRNATLGSEETTEHAPSDASTTEGKLMELGHKIMKNLENTVKEIIKYLKSLFPPASEVVKP
What are the official names of this protein?
Glycosylation-dependent cell adhesion molecule 1, GlyCAM-1, 28 kDa milk glycoprotein PP3, Lactophorin, Proteose-peptone component 3, PP3.
What is the protein family that this protein belongs to?
Belongs to the PP3/GlyCAM-1 family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: RPPH_SERP5
Sequence: MIDDDGYRPNVGIVICNRQGQVLWARRYGQHSWQFPQGGINPGETAEQAMYRELFEEVGLSKKDVRILASTRNWLRYKLPKRLVRWDTKPVCIGQKQKWFLLQLMCNDADINMQRSSTPEFDGWRWVSFWYPVRQVVSFKRDVYRRVMKEFAVTVMPMQEQAAQRQTPAYRRKRG
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: NSCC_ARTGP
Sequence: MAKQQRTVLIIGAGIAGLTTSRLLTNNGIPNIVFEASTPDRSQGFAISLQEFGYSTLLSALGDLPLSSLIKGVAPDRVIGGTGWIDQALRDNRTGELLVAPELTTTKQTVVRANRNALRQWIADCGDEELDVRYGHKLQRVEGKAGNITAVFENKAKYNGSLIIAADGVNSTVRSQVLPSVVPETIPLIHYHGEFQLSRTKFDELIRPYSGHSNILVGVGDRFNTPLSICNMSKSHVHLDWSYSRTVKEGNDLLYRPNLPSEEAKKIPLALVEELGALDLAGPWKHFLNPESLKSHRVFHWTTRCVYMTQDDARSAGEKGIVFVGDSWHAMPIFGGEGGNHALLDGVELSNAIVTAMASTEKDYWSKAVASYYSSAWKRSQEAVRRSTQRFFLLHRPAADWREIAEKKRRTT
What is the function of this protein?
FAD-dependent monooxygenase; part of the gene cluster that mediates the biosynthesis of neosartoricin B, a prenylated anthracenone that probably exhibits T-cell antiproliferative activity, suggestive of a physiological role as an immunosuppressive agent (PubMed:23758576).  The non-reducing polyketide synthase nscA probably synthesizes and cyclizes the decaketide backbone (By similarity).  The hydrolase nscB then mediates the product release through hydrolysis followed by spontaneous decarboxylation (By similarity).  The prenyltransferase nscD catalyzes the addition of the dimethylallyl group to the aromatic C5 (By similarity).  The FAD-dependent monooxygenase nscC is then responsible for the stereospecific hydroxylation at C2 (By similarity).  Neosartoricin B can be converted into two additional compounds neosartoricins C and D (By similarity).  Neosartoricin C is a spirocyclic compound that is cyclized through the attack of C3 hydroxyl on C14, followed by dehydration (By similarity).  On the other hand, neosartoricin D is a further cyclized compound in which attack of C2 on C14 in neosartoricin C results in the formation of the acetal-containing dioxabicyclo-octanone ring (By similarity).  Both of these compounds are novel and possibly represent related metabolites of the gene cluster (By similarity).
What are the official names of this protein?
FAD-dependent monooxygenase nscC, Neosartoricin B biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the paxM FAD-dependent monooxygenase family.
Protein: RSMJ_YERPS
Sequence: MSHVSICLLSEAGADPGALSILADRWGLVSDDQAVMALVLTAERLELRKRDEPKLGGIYVDFVSGTQAHRRKFGGGRGEAVAKAVGIKKGYLPRVVDATAGLGRDAFVLAALGCQVQMLERNPVVAALLDDGLRRGYLDAEIGPWLRERLTLLHASSLTALVAIEPRPEVVYLDPMYPHRQKSALVKKEMRVFQSLVGADNDADGLLAPARALATKRVVVKRPDYAEPLAGVAAQAAVVTKSHRFDIYPSSVTPPR
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.