PharMolix/UniProtQA huggingface dataset:
Protein: CHI3_METRA
Sequence: MFVRNALVVTGLLAALTQAAPAERNTSRHKLTVYWGAEDDTTTLDDVCNDSSYDVVNLAFLSHFFSGGGYPRMSIGNLDGPSRAQKKAGATGLQDGSSLVKSIKNCQSKGKPVILSMGGATDYSDVQLHSDAQGQQIANTVWDLFLGGTDHKELRPFGDVKLDGVDLDNETNDGTGYLAMAKQFKANFQKDTSKKYYITAAPQCPYPDQSEPLDVCRLLDWVQVQFYNNGNCNIAQSGFATAVKNWSRGIGSGVQLYIGALASGADGDEGYVDAAVLNRAIDQVKAMDLPNFGGAMLWEAQLAVNNGNYQKEIKANL
What is the function of this protein?
Secreted chitinase involved in the degradation of chitin, a component of the cell walls of fungi and exoskeletal elements of some animals (including worms and arthropods).  Participates in the infection process and directly acts in the penetration process of the host cuticle.  Involved in heat-shock adaptation (By similarity).
What are the official names of this protein?
Endochitinase 3, Chitinase 3.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family. Chitinase class III subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: FLIG_SHIBO
Sequence: MSNLTGTDKSVILLMTIGEDRAAEVFKHLSQREVQTLSAAMANVTQISNKQLTDVLAEFEQEAEQFAALNINANDYLRSVLVKALGEERAASLLEDILETRDTASGIETLNFMEPQSAADLIRDEHPQIIATILVHLKRAQAADILALFDERLRHDVMFVSHLWRRAASALAELTEVLNGLLDGQNLKRSKMGGVRTAAEIINLMKTQQEEAVITAVREFDGELAQKIIDEMFLFENLVDVD
What is the function of this protein?
FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body.  This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity).
What are the official names of this protein?
Flagellar motor switch protein FliG.
What is the protein family that this protein belongs to?
Belongs to the FliG family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Bacterial flagellum basal body.
Protein: P4HA3_MOUSE
Sequence: MGPGARLALLALLALGGDPAAATGREDTFSALTSVARALAPERRLLGTLRRYLRGEEARLRDLTRFYDKVLSLHEDLKIPVVNPLLAFTVIKRLQSDWRNVVHSLEATENIRALKDGYEKVEQDLPAFEDLEGAARALMRLQDVYMLNVKGLARGVFQRVTGSSITDLYSPRQLFSLTADDCFQVGKVAYDTGDYYHAIPWLEEAVSLFRRAHGEWKTEDEASLEDALDYLAFACFQVGNVSCALSLSREFLVYSPDNKRMARNVLKYERLLAENGHQMAAETAIQRPNVPHLQTRDTYEGLCQTLGSQPTHYQIPSLYCSYETNSSPYLLLQPARKEVVHLRPLIALYHDFVSDEEAQKIRELAEPWLQRSVVASGEKQLQVEYRISKSAWLKDTVDPMLVTLDHRIAALTGLDIQPPYAEYLQVVNYGIGGHYEPHFDHATSPSSPLYRMKSGNRVATFMIYLSSVEAGGATAFIYGNFSVPVVKNAALFWWNLHRSGEGDGDTLHAGCPVLVGDKWVANKWIHEYGQEFRRPCSTNPED
What is the function of this protein?
Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
What are the official names of this protein?
Prolyl 4-hydroxylase subunit alpha-3, 4-PH alpha-3, Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-3.
What is the protein family that this protein belongs to?
Belongs to the P4HA family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: STS1_METRA
Sequence: MNVLLSPQPPVFPHHHENPRLSPQRSVSPLLGMSNRKRKADDDGDETMSPLSSPAISARPLVRPSKKVRSNELIGRPLPLPRLLETLDASQLRMVLERLCERHPDIGQEVVVGAPRPSVLSALDVLQDYHVKLKEAIPYGESSPEYTYYRVKEPLIALIDALSDFTPQYLPPMETQPTTSLQFLDGATKLIHDLPNWEPQAYRHHKESAYDDISRAWALVITEAGKRGGGLNLHTGGWDQTLSRHNEQSGGRLGTAMSAMASSVGWMGPGLSTQGNPSEQNSILNRLMSGSYGSPVRVGPW
What is the function of this protein?
Involved in ubiquitin-mediated protein degradation.  Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates.  Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins (By similarity).
What are the official names of this protein?
Tethering factor for nuclear proteasome STS1.
What is the protein family that this protein belongs to?
Belongs to the cut8/STS1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: KPRS_CHRVO
Sequence: MAAYDSLMVFTGTANPELAQNVVKHLDISLGRADVGKFSDGEVAVELLENVRGRDVFILQSTCAPTNDNLMEILTMADALKRASAGRITAAIPYFGYARQDRRPRSARVPISAKLVANMLTSAGIDRVLTVDLHADQIQGFFDIPVDNVYATPVLLKDIRAQRFDDLIVVSPDVGGVVRARAVAKALNTDLAIIDKRRPKANVAEVMNIIGDVSGRTCLIVDDMIDTANTLCKAASALKERGAERVLAYATHAIFSGQAVDRIKNSDIDMVVVTDTIPLTAAAKACPNIRVASIAGLLAETLRRINNEESVSYLFNEELVATGACLP
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase, RPPK, 5-phospho-D-ribosyl alpha-1-diphosphate synthase, Phosphoribosyl diphosphate synthase, Phosphoribosyl pyrophosphate synthase, P-Rib-PP synthase, PRPP synthase, PRPPase.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GP171_RAT
Sequence: MTNSSMFCPIYRDLEPFTYFFYLVYLIGIIGSCFATWAFIQKSTNHRCVSIYLINLLTADFLLTLALPVKIVVDLGVAPWKLRIFHCQVTACLIYINMYLSIIFLAFVSIDRCLQLVHSCKIYRIQEPGFAKMISAVVWLMVLLIMVPNMVIPIKNIKEKSNVGCMEFKREFGKNWHLLTNFICVAIFLNFSAIILISNFLVIRQLYRNRDNANYPSVKSALLNILLVTASYIICFVPYHAVRIPYTLSQTEVISDCSTRIALFKAKEATLLLAVSNLCFDPILYYHLSKAFRLKVTETFASPQKMKAREEKPRRENDVQSTGSAC
What is the function of this protein?
G-protein coupled receptor for Big LEN, a 16-amino acid neuropeptide produced from the precursor protein, proSAAS (encoded by PCSK1N) (PubMed:24043826).  Acts through a G(i)-alpha-mediated pathway in response to Big LEN.  Big LEN-GPR171 system plays an important role in regulating feeding and metabolism.  Also plays a role in modulating fear and anxiety-like behaviors in the basolateral amygdala.  Big LEN-GPR171 modulates the mu-type opioid receptor signaling and antinociception.  Acts as a negative regulator T cell function (By similarity).
What are the official names of this protein?
G-protein coupled receptor 171.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Colocalized with GPR83 in the paraventricular nucleus.
Protein: 53DR_BORBR
Sequence: MLILLDQDGVLADFEHAFIDAWRKRHPDIEPVAFKDRKSFHIREDYAPELRGLAEAIYTAPGFIRDLPPVPGAIEAFRELLALGMDVRICSSPLMQFENCVAEKYLWVERHLGREATQRLILTRDKTLVQGDLLIDDRPVITGAARPRWRHIIYDAPYNRDQTDRPRLDWRNWRNVLAGELYRSDA
What is the function of this protein?
Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides.
What are the official names of this protein?
Putative 5'(3')-deoxyribonucleotidase.
What is the protein family that this protein belongs to?
Belongs to the 5'(3')-deoxyribonucleotidase family.
Protein: RELX_MACMU
Sequence: MPRLFLFHLLGVCLLLNQFSRAVAAKWMDDVIKACGRELVRAQIAICGKSTLGKRSLNQEDAPLKPRPAAEIVPSLINQDTETINMMSEFVANLPQELKLTLSERQPALSELQQHVPVLKDSNLSFEEFKKIIRKRQSEATDSSPSELRSLGLDTHSRRKRQLYMTLSNKCCHIGCTKKSLAKFC
What is the function of this protein?
Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals.  May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix.
What are the official names of this protein?
Prorelaxin.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y097_STRMK
Sequence: MTDSVQTPDVPLLDAVQARLLGCLVEKEATTPDTYPLTVNAAQSAANQKTAREPVMNIDAGSVQHALRQLEALGLARQHFSSRADRYEHRLQAALDLTRQQTVLLALLLLRGPQTLGELITRSERLHRFADTDEARHAIERLQQRALLVVLPRASGQREDRYMHLLCGEVDGAALAARYASSGGGSSDAADPGLAERVAQLEAAVAELQAQLAELRG
What are the official names of this protein?
UPF0502 protein Smlt0097.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: SYT_HAMD5
Sequence: MPVITLPDGSTRHYEQSLSVLDVALDIHPRLAKSCIAGRFNDQLIDACDLLSVDGKLQIITPSDGEAVEIIRHSCAHLLGHAVKQLWPETKMAIGPVIENGFYYDLDIESPLTQEDLELLEKRMHELAHKNYTVIKKKVSWQKARDTFSKRGESYKIAILDENIDSSDQPNLYFHEEYIDMCRGPHVPNMSFCHYFKLQKTSGAYWRGDSKNKTLQRVYGTAWSDKKQLDAYLNRLEEATKRDHRKIGKTQDLYHFQEEAPGMVFWHENGWIVFRELEILIREKLKEYEYQEVKGPFMMDRVLWEKTGHWENYSENMFTTLSENREYCIKPMNCPGHLEIFKQGLKSYRDLPLRMAEFGSCHRNEPSGALHGLMRVRGFTQDDAHIFCTEKQVRKEVSNCIKMTYDIYQTFGFKKIAVKLSTRPEKRIGSDEIWTQAEEDLASVLKEQGITFELQPGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPVRLNAFYIDENSERQVPVMIHRAILGSIERFIGILTEEYAGFFPVWLAPVQVMLINITEKQSDYVKKVAKNLQQLGVRAKVDLRNEKIGFKIRQHTLYRIPYILVCGDKEVESNQIAVRTHSGKDLGSFSVNVFADKLLEEISSRCLH
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BTRV_BORBR
Sequence: MKLTMDKIDGMLIACLQGVVNSANAEQLEAELAAQVDKGERRVVLDLGRLDYISSAGLRVVLLVAKQLRQVQGELVLCELKPHVREVFEISGFLSIFPVANSREAAAAAFKTALPR
What is the function of this protein?
Possible positive regulator of sigma-B activity (By similarity).  Non-phosphorylated BtrV binds to BtrW, preventing its association with an unknown partner(s) that might be sigma-B.  When phosphorylated, releases BtrW, which is then free to complex with and inactivate its partner.  Involved in type III secretion system (TTSS).
What are the official names of this protein?
Putative anti-sigma factor antagonist BtrV.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-factor antagonist family.
Protein: Y1077_YERPE
Sequence: MPKRTYAMRYVAGQPVEQIFPGAAKQLDKGLPLGEPLPTAELLRVVVWNIFKQQRAGWLPVLKELGRDTQLMLLQEAQTTPELVRFATASYQAADQVPAFSLPQHPSGVMTLAAAHPVYCCPLREREPLLRLSKSALVTVYPIHDGRLLMVVNIHAVNFSLGVDVYSKQLDPIGDQIASHRGPVILAGDFNAWSRQRINALQHFAQDAGLQEVEFRVDHRSRAFGRPLDFIFYRGLTVIDASVLVTRASDHNPLIVEFQP
What are the official names of this protein?
UPF0294 protein YPO1077/y3099/YP_2772.
What is the protein family that this protein belongs to?
Belongs to the UPF0294 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_SALTI
Sequence: METIAKHRHARSSAQKVRLVADLIRGKKVSQALDILTYTNKKAAVLVKKVLESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: THIC_RHOPB
Sequence: MNIRSNPDTTLPAVTTGPLPSSRKIFATPDEAPELRVPLREIILSDGAGEPNLPVYDTTGPYTDPSVTIDVNAGLSRIRTAWVKERGGVEEYQGRDVKPEDNGNVGAAHAAKSFTAYHKPLRGLDAPAAGTANSPPPRGEGSGVGGATNTVPSSTPLPTPPPQGGREQGIAYACGPHLPPMVTQLEFARAGIITKEMIYVATRENLGRKQQLARAEAALADGESFGASVPAFVTPEFVRSEIARGRAIIPANINHGELEPMIIGRNFLTKINANIGNSAVTSSVEEEVDKMVWAIRWGADTVMDLSTGRNIHTTREWILRNAPIPIGTVPIYQALEKCEGDPVKLTWELYRDTLVEQCEQGVDYFTIHAGVRLAYIHLTANRTTGIVSRGGSIMAKWCLAHHQESFLYTHFDEICDLMRKYDVSFSLGDGLRPGSIADANDRAQFAELETLGELTKIAWDKGCQVMIEGPGHVPLHKIKINMDKQLKECGEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPDRNDVKVGVITYKIAAHASDLAKGHPAAQLRDDALSRARFDFRWQDQFNLGLDPDTAQAFHDETLPKDAHKVAHFCSMCGPKFCSMKITQDVRDYAAGLGDNEKAALNLAGGSSLGSVGMSISGKLEDGLPADAFAKAGMAEMSEKFRTMGEQLYLDAEKVKESNKALS
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: CYCP_RHOSP
Sequence: DGMETVKARQDYFKSLGGAMKALSGVAKNYDAEAAKAEAAKLEAILATDIKPLFAPGTSDADFPGESEAKASIWENMEDFGAKGQAMHEAGMELIAAANTGEASAFGPALKKLGGTCKACHDDYRAEH
What is the function of this protein?
Cytochrome c' is the most widely occurring bacterial c-type cytochrome.  Cytochromes c' are high-spin proteins and the heme has no sixth ligand.  Their exact function is not known.
What are the official names of this protein?
Cytochrome c'.
Protein: SESQ1_RAT
Sequence: MKLNERSLAFYATCDAPVDNAGFLYKRGGRGAGSHRRWFVLRGNILFYFESESSREPLGVILLEGCTVELVDAREEFAFAVRFAGGRSRPYVLAADSQAALEGWVKALSRASFHYLRLVVRELEQQLAAMREGSPANALPDANPSTVLNPKPKENGRAVWSALPEQPAVAPRRPPLPPRRRASAANGPSVSFAQLHERYGLEVRALRNQWRGGLTSLEVPCHPGSGETQTQDQP
What is the function of this protein?
Plays a role in endocytic trafficking.  Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
What are the official names of this protein?
Sesquipedalian-1, Ses1, 27 kDa inositol polyphosphate phosphatase interacting protein A, IPIP27A, PH domain-containing endocytic trafficking adaptor 1.
What is the protein family that this protein belongs to?
Belongs to the sesquipedalian family.
What are the subcellular locations of this protein?
Early endosome. Recycling endosome. Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle, clathrin-coated vesicle. Note=Interaction with OCRL may be crucial for targeting to endosome and to the trans-Golgi network. Also found on macropinosomes. Not detected in late endosomes, nor in lysosomes.
Protein: MIAB_SODGM
Sequence: MTKKLHIKTWGCQMNEYDSSKMADLLDSTHGYQLTDNPEEADVLLLNTCSIREKAQEKVFHQLGRWHMLKEARPELIIGVGGCVASQEGAHIRERANYVDIIFGPQTLHRLPEMINHVNGTRSPVVDISFPEIEKFDRLPEPRAEGPTAFVSIMEGCNKYCSFCVVPYTRGEEVSRPCDDILFEIAQLADQGVREVNLLGQNVNAYRGASYDGGICTFAELLRLVAAIDGIDRIRYITSHPIEFTDDIIDVYRDTPELVSFVHLPVQSGSDRILTMMKRAHTALEYKSIIRRLRKARPDIQISSDFIIGFPGETQQDFEQTMQLIADVNFDMSFSFIYSARPGTPAADMVDNVSEEEKKQRLHILQERITQQAMQYSRRMKGKVQRILVEGTSRKNVMELSGRTENNRVVNFEGAPSMIGKFVDVEIVDVYPNSLRGVLLRTEDQMTLRSHESTASVIARTRKENELGVGMYQP
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_SACEN
Sequence: MSKGKRTFQPNNRRRARKHGFRLRMRTRAGRAIVAGRRRRGRASLTA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: SSB1_KLULA
Sequence: MAEGVFPGAIGIDLGTTYSCVATYENSVEIIANEQGNRVTPSFVAFTPEERLIGDAAKNQAALNPKNTVFDAKRLIGRRFDEESVQSDMKTWPFKVIDSNDAPLIEVEYLGETKTFSPQEISSMVLTKMKEIAEAKIGKKVEKAVVTVPAYFNDAQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLGAGKSDKERHVLIFDLGGGTFDVSLLHIAGGVYTVKSTSGNTHLGGQDFDTNLLEHFKTEFKKKTGLDISGDARALRRLRTAAERAKRTLSSVAQTTVEVDSLFDGEDFEATITRARFEDINAALFKSTLEPVEQVLKDAKIAKSQIDEVVLVGGSTRIPKVQKLLSDFFEGKQLEKSINPDEAVAYGAAVQGAILTGQSTSDETKDLLLLDVAPLSLGVGMAGDVFGVVVPRNTTVPTIKRRTFTTVADHQTTVTFPVYQGERVNCKENTLLGEFDLKGVPPMPAGEPVLEAIFEVDANGILKVTAVEKSTGKSANITISNAIGRLSSEEIEQMVNQAEEFKAADEAFAKKHEARQRLESYISSVEQTVTDPVLSAKIKRNAKAKVEAALAEAFSTLQIEDASTDDLRKAEVGLKRAVTKAMSTR
What is the function of this protein?
Ribosome-bound, Hsp70-type chaperone that assists in the cotranslational folding of newly synthesized proteins in the cytosol.  Stimulates folding by interacting with nascent chains, binding to short, largely hydrophobic sequences exposed by unfolded proteins, thereby stabilizing longer, more slowly translated, and aggregation-prone nascent polypeptides and domains that cannot fold stably until fully synthesized.  The Hsp70-protein substrate interaction depends on ATP-binding and on allosteric regulation between the NBD and the SBD.  The ATP-bound state is characterized by a fast exchange rate of substrate (low affinity state), while in the ADP-bound state exchange is much slower (high affinity state).  During the Hsp70 cycle, the chaperone switches between the ATP-bound state (open conformation) and the ADP-bound state (closed conformation) by major conformational rearrangements involving mainly the lid domain.  Ssb cooperates with a specific Hsp40/Hsp70 co-chaperone termed the ribosome-associated complex (RAC), which stimulates the ATPase activity of the ribosome-associated pool of Ssbs and switches it to the high affinity substrate binding state.  Hsp110 chaperone SSE1 and FES1 act as nucleotide exchange factors that cause substrate release.
What are the official names of this protein?
Ribosome-associated molecular chaperone SSB1, Heat shock protein SSB1, Hsp70 chaperone Ssb.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family. Ssb-type Hsp70 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with translating ribosomes.
Protein: FA83G_MOUSE
Sequence: MAFSQVQCLDDNHVNWRSSESKPEFFYSEEQRLALEALVARGRDAFYEVLKRENIRDFLSELELSRIVEAIEVYDPGSEDPRVSGRRPEPQDNGGADASEETSAAGGPPATETLPSLEYWPQKSDRSIPQLDLGWPDTIAYRGVTRASVYMQPPIDGQPHIKEVVRKMVSQAQKVIAVVMDMFTDVDIFKDLLDAGFKRKVAVYIIVDESNVKYFLHMCERARMHLGHLKNLRVRSSGGTEFFTRSATKFKGVLAQKFMFVDGDRAVCGSYSFTWSAARTDRNVISVLSGQVVEMFDRQFQELYLMSQSVSLKDIPMEKEPEPEPIVLPSVVPLVPTGTMAKKLVNPKYALVKAKSVDEIAKSSSDKQEVTRPPGLRGPAVAERPGDLSELLPPVHPGLLNLERANMFEYLPTWVEPDPEPGSDILGYINIIDPNIWNPQPNQMNRIKIRDTAHASAQHQLWKQSQGARPCPAPCPPPAPRDSQGVVPAENGFPQGNPEPQAPVPKPRTVPVASVLARDGSDIGWALDTPEKETPQNGIDPRLPSTASESEVPQQQHSSMTQDDPDGLERGLPNGLDEDEDDDDDYVTLSDQDSLSGSSGPGPGHRRPSVASSMSDEYFEVRERSVPLQRRHSEQMANGPGHPPRRQLSAPHVTRGTFGGPLSSPLWAQGRSREDVDASRIQGQRPMDRQAQGQHFHRHGSTTSRTPGPPRFRPAADGTQSSSKKASPAAAGPHHWQPKGSPTPRMLPDPGSPRPTRNTRLRAELRATEEHASPFGIPYSKLSQSKHLKARAGGSQWAPSDSKRRARDHKEP
What is the function of this protein?
May regulate the bone morphogenetic proteins (BMP) pathway.
What are the official names of this protein?
Protein FAM83G.
What is the protein family that this protein belongs to?
Belongs to the FAM83 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Note=Detected predominantly in cytosolic. Upon BMP stimulation, a small portion of PAWS1 is detected in the nucleus.
Protein: MATK_QUESU
Sequence: MEEFQGYLELDRFRQHDFLYPFIFREYSYALAHGHGLNRYMLLENIGYDNKSSLLIVKRLITTMYQQNYLIISANDSKKNPFFGYNKNLHSKILSEGFAIIVEIPFYLRLISSLEGAEIVRFYNLRSIHSIFPFLEEKFPHLNYSADILIPYPAHLEILVQTLRYRVKDASYLHLLRFFLHEYSNCNSLIITNKSISIFSKSNPRFFLFLYNSYLCEYESIFLFLRNQSSHLRLTSSGVLFERLCLYRKIEHFAEVFANDFPVIPCFLKDPFMHYVRYQGKSILASKDTPLLMNKWKSYLVNLWQCHFDVWSHAASIRINQLSKHSLDFLSYFSSVRRNPAVVRNQMLENSFLLNNAPNKLDTIVPIIPLIGSLAKAKFCNAVGHPISKLTRADLSDFEIINRFLHICRNLSHYYSGSSKKKNMYRIKYILRLSCVKTLARKHKSTARAFLKRVDSEFFQEFFTEEGGFISLIFPRASFALRRLYSGRVWYLDIIFINGLSNHE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL2_ACIF5
Sequence: MALIKTKPTSAGRRFVVKTIDTRLHKGNPHSALVEVQSHSGGRNNLGRVTRRHQGGGHKSHYRLVDFKRNKLDIPGKVERLEYDPNRSAHIALICYVDGERRYILAAKGMSVGDPVLSAEQTPIKPGNCMPLRGIPVGSVVHNVEMRPGKGGQIARSAGASVQLMAREGDYAQLRLRSGEVRRIHVSCRATIGEVGNEEHGSRQLGKAGATRWRGVRPTVRGVAMNPVDHPHGGGEGRTSGGRHPVSPWGQPTKGYRTRRNKRTSNMIVRRRSR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: PROB_BACAN
Sequence: MKKQRIVVKIGSSSLADSHEGISKEQLSDHVAALARLKEEGHEVLLITSGAVAAGFSALGYPSRPVTIKGKQAAAAVGQSLLMQAYTEEFRKYGIVTAQLLLTRSDFSRKEQYSNAYATLGELLNRSALPIINENDSISLEELTFGDNDMLSALVSGLVSADMLMIFTDVNGLYDKNPQKNEDAKKYYFLPEVTEEIASLAGDAGSKLGTGGMKSKVDAAKTALSLGVSVFIGTGRGQEKFVDVLKGKGDGTYVGNAPQKEMKINKQWIALHSVVSGQIEIDAGAATAIIQHGKSLLPAGVTNVSGFFQVGEVVEVMTQQGRVIGKGQCTYSAEELRDVKGMQSQQIQARGERHNYEVIHRDYWVSF
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOP6A_SULTO
Sequence: MSSELTSKVDKEARKKAADTLRQVFVKLIEQINNSEPPTMEIPKRTLGNTIYDEKRKLLLLGEEKLKRSFFDLNESKRFMQTVLMASIIYDALINDEYPTIRDLYYRGKHSIILKDPRGKTYEENTWDEQKESDSVIMDIEVFTSLLREDMLILSKEKGKVVGDMRIRSGNDIIDLSKMGHGAYSIEPTPDLIDFVDINAEFVLVVEKDAVFQQLHRAGFWKQYKAILVTSAGQPDRATRRFVRRLNEELKLPVYILTDADPYGWYIYSVFRIGSISLSYESERLATPNAKFLGVSMTDIFGDSNKKPYLSEQERRNYIIKAKDADIKRATEIKNYQWFKTKAWQHEIEIFLNKKSKLEIEAMASKGLKFLAFQYIPEKIKSKDYIE
What is the function of this protein?
Relaxes both positive and negative superturns and exhibits a strong decatenase activity.
What are the official names of this protein?
Type 2 DNA topoisomerase 6 subunit A, Type II DNA topoisomerase VI subunit A.
What is the protein family that this protein belongs to?
Belongs to the TOP6A family.
Protein: SUCD_BACSU
Sequence: MSVFINKDTRVIVQGITGSTALFHTKQMLEYGTNIVGGVTPGKGGTEAEGVPVFNTVAEAVQTTGANASVIYVPAPFAADAIMEAVDAELDLVICITEHIPVLDMVKVKRFMEGKKTRLIGPNCPGVITPEECKIGIMPGYIHKKGHVGVVSRSGTLTYEAVHQLSEAGVGQSTAVGIGGDPVNGTNFIDVLKAFNEDPDTHAVIMIGEIGGTAEEEAAEWVKANMTKPVVGFIGGKTAPPGKRMGHAGAIISGGKGTADEKIKTLNACGIEVAETPSVMGETLIKVLKEKNLFETCKTH
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit alpha, Succinyl-CoA synthetase subunit alpha, SCS-alpha.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase alpha subunit family.