PharMolix/UniProtQA huggingface dataset:
Protein: TRMB_DROAN
Sequence: MARDSEDQDMETETNGAAEGLDPTSAVTGLPQKRFYRQRAHSNPIADHSFDYPARPEDVNWRALYPSIQPDQKVTFADIGCGYGGFLVTLGEMFPEKFSIGMEIRVKVSDYVMDRITALRHKSGEAGAYKNIACLRTNAMKYLPNYFAKGQLEKMFFLYPDPHFKRAKHKWRIINQALLSEYAYVLKKGGLVYTMTDVEDLHQWIVQHMEEHPLYERLKEEEEQSDPITPKLYQSSEEGAKVVRNKGDHFLAIFRRL
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL23_PSELT
Sequence: MNQQKLTHYDILIKPITTEKTMLDREKRKYVFEVNVLSNKALVKNAVESLFNVKVEKVNISLVKPKPKRRGRFEGKTRRWKKAVVTLKEGYTIKELEGQQ
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: ZAPD_YERPB
Sequence: MSDLTSTILFEHPLNEKMRTWLRMEFLLQQLESHRSLDNIANALTFFRTASDLIDVLERGEVRTDLLKELERQQQKLQQWADIPGVDVSLVDSLRNQLKSRAAVLMSAPRIGQSLKEDRLISVVRQRLSIPGGCCSFDLPTLHVWLHQPSEQRDQHINKLLASLAPLHQSLTIILDLIRQSCPLRSQISLNGFFQDNAGGADLLRLRLPLDPQLYPQISGHKTRYAIRFLALDSENGTVPARLSFELACC
What is the function of this protein?
Cell division factor that enhances FtsZ-ring assembly.  Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
What are the official names of this protein?
Cell division protein ZapD, Z ring-associated protein D.
What is the protein family that this protein belongs to?
Belongs to the ZapD family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to mid-cell in an FtsZ-dependent manner.
Protein: Y537_PARP8
Sequence: MDARLLEILVCPICKGPLSYDRAAQELICNADKLAYPIRDGIPVMLVDEARQTVEGTPVDLNPGSVA
What are the official names of this protein?
UPF0434 protein Bphy_0537.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: RS17_CHLTB
Sequence: MASDVRGRRKTKIGVVVSSKMEKTVVVRVERVYSHPQYAKVVRDSSKYYAHNELDVKEGDTVRIQETRPLSKTKRWRVVGRVN
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: SUFB_ECOLI
Sequence: MSRNTEATDDVKTWTGGPLNYKEGFFTQLATDELAKGINEEVVRAISAKRNEPEWMLEFRLNAYRAWLEMEEPHWLKAHYDKLNYQDYSYYSAPSCGNCDDTCASEPGAVQQTGANAFLSKEVEAAFEQLGVPVREGKEVAVDAIFDSVSVATTYREKLAEQGIIFCSFGEAIHDHPELVRKYLGTVVPGNDNFFAALNAAVASDGTFIYVPKGVRCPMELSTYFRINAEKTGQFERTILVADEDSYVSYIEGCSAPVRDSYQLHAAVVEVIIHKNAEVKYSTVQNWFPGDNNTGGILNFVTKRALCEGENSKMSWTQSETGSAITWKYPSCILRGDNSIGEFYSVALTSGHQQADTGTKMIHIGKNTKSTIISKGISAGHSQNSYRGLVKIMPTATNARNFTQCDSMLIGANCGAHTFPYVECRNNSAQLEHEATTSRIGEDQLFYCLQRGISEEDAISMIVNGFCKDVFSELPLEFAVEAQKLLAISLEHSVG
What is the function of this protein?
The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS.  The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress.  May facilitate iron uptake from extracellular iron chelators under iron limitation.
What are the official names of this protein?
FeS cluster assembly protein SufB.
What is the protein family that this protein belongs to?
Belongs to the UPF0051 (ycf24) family.
Protein: RECO_RHOPB
Sequence: MEWTDEGIVLGVRRHGESSAIVELLTRGHGRHLGLVRGGAGSKLRPLLQPGNSVSAVWRARLDEHLGYYVLEGTRMRAAMLLASSHAVYGVTHLASLARLLPERDPQPEIYERLERTLDDFDDVGEAAVHVIRFELTMLAELGFGLDLANCAATGVTSDLIYVSPKSGGAVSRAAGEPWRDKLLRLPPFLREGSAQRNDWSDQDLQDGFLLTGRFLLRNVLEPRGQGHSDARDGFINAVVRLRTRELAETAPPK
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: RS13_METCA
Sequence: MARIAGVNIPDHKHVLISLTAIYGIGRTRAGLICKNAGIETDKKVRELSDEQVERLRGEVAKFVVEGDLRREVAMNIKRLMDLGSYRGMRHRRGLPVRGQRTRTNARTRKGPRRPIKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: SHE9_YARLI
Sequence: MLTRRMQCLRGAGVFRTVAALPLLAQRPNFYRPLTCSALRRNNDHSYRHESRKDKEMQDLKESRKMREQEALDDAAFRNTFEFAVEKTRDSDGKSPEPEVEIDVDREAQTPWDPVGSQSRHETRQEHRERFDDIKKTLPSSVHESQPQMYKWFGEKMDQIQAGALTAGQTLNEVTGYKAIEKLKLSIEKLEDEVLEARAEVREAKRMYSDAISERSNSQREVNELLQRKHNWTPADLERFTELYRNDHANEHSVNDAKKRLGECEHHVEDLTLQLSKQILTRYHEEQIWSDKIRRASTWGTWILMGFNVVLFIVVQLGLEPWKRRRLVGSFEDKVKESLQEWEARNEARRLEEATMAATATQAITELQRRIESPHVSKADVVEAEAEINSIKTNLATWFKEREEEEKEEIAKEAHELAVIAEDPDMTDVHHKPHPPQPVDTERVVRPHLVENFEHHVADPVHHPTLPITSTPVLEEDAPPPRIHPLVQMSPDSPDDGTKTFTATRDGYDVHPLVVRPTTPPHFMLQVWGAAKLSVESATNKTVAVVRSTFQTAEQRPFESTIVASLGGLCGGLVTFLYLR
What is the function of this protein?
Required for the maintenance of the structure of the mitochondrial inner membrane.  Involved in mitochondrial morphology.  Causes growth arrest when highly overexpressed (By similarity).
What are the official names of this protein?
Sensitive to high expression protein 9 homolog, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the SHE9 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: LUR1L_HUMAN
Sequence: MEDSPLPDLRDIELKLGRKVPESLVRSLRGEEPVPRERDRDPCGGSGGGGGGGGGCSSSSSYCSFPPSLSSSSSSSPTSGSPRGSHSSALERLETKLHLLRQEMVNLRATDVRLMRQLLVINESIESIKWMIEEKATITSRGSSLSGSLCSLLESQSTSLRGSYNSLHDGSDGLDGISVGSYLDTLADDVPGHQTPSDLDQFSDSSLIEDSQALHKRPKLDSEYYCFG
What are the official names of this protein?
Leucine rich adaptor protein 1-like.
Protein: NUF2_NEUCR
Sequence: MAFNPRMSILPPQPQQSRQRKKEEEAAYANMRLPDREIVGCINELGIPFTLADLQKPNPIQVQMIFEWFGELLMNKTRQTVDPAMRAAAEDVCGPELGEAMMPSDTRNLLGFYVSLRRLMLDCGVNDFSFNDLYKPTHDRLVRMLSYVINFVRFRESQTSVIDEHCNKAEQTKARIEQLYVENQNMEAQLEEMRHNRRAMEVLVQEKTVRNEELKKRLLELRRSQEKVAARLEEAKTKKGELAAELEEKTATKIALKQESAKLRPYVLQSPSALQASLAELSNTLNNDKAHIDALDRRSRALQTSTDSFSVVASDVASCIKLLEEIAIELAKEEEENVKNARQRDALTERGHNVREVERTEALLKRQLAKWVDRTAQLRTQSEEKAQKAMEKMEELRAVHRKLTEERSEKGKDIERRRVRIEQTEKKMLDLKENIENEVHAAHDEYLKMEAHIKLYITEMEQAI
What is the function of this protein?
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
What are the official names of this protein?
Probable kinetochore protein nuf2, Kinetochore protein 2.
What is the protein family that this protein belongs to?
Belongs to the NUF2 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with kinetochores.
Protein: EMBC_MYCSM
Sequence: MTGPHAAGGSNHRTARLVAIIAGLLGTLMAIATPLLPVEQTTAELNWPQNGVWQSVDAPLIGYVATDLTVTVPCQAAAGLVGPENRNRSVLLSTVPKQAPKAIDRGLLIERINNDLTVIVRNTPVVSAPLEQVLSPDCRYLTFTAHADKVTGEFVGLTQGPDDDDPGEAVRGERSGYDFRPQIVGVFTDLSGPAPEGLQLSATIDTRYSTSPTLLKLLAMIVGVAMTVIALGALHVLDCADGRRHKRFLPSRWWSMTPLDGLVSAMLVWWHFVGANTADDGYILTMARVSEHAGYMANYYRWFGTPESPFGWYYDLLALWAHVSTASVWMRFPTLLMGLACWWVISREVIPRLGAAAKHSRAAAWTAAGLFLAFWLPLNNGLRPEPIIALGILLTWCSVERGVATSRLLPVAVAIIIGALTLFSGPTGIAAVGALLVAIGPLKTIVAAHVSRFGYWALLAPIAAAGTVTIFLIFRDQTLAAELQASSFKSAVGPSLAWFDEHIRYSRLFTTSPDGSVARRFAVLTLLLALAVSIAMTLRKGRIPGTALGPSRRIIGITIISFLAMMFTPTKWTHQFGVFAGLAGCLGALAAVAVTTTAMKSRRNRTVFGAAVLFVTALSFATVNGWWYVSNFGVPWSNSFPEFKFGFTTMLLGLSVLALLVAAWFHFSGRDVSPDRPQRRWQRLLVAPLAVATWALVIFEVVSLTLGMINQYPAWSVGRSNLNALTGKTCGLANDVLVEQNANAGMLTPIGEPAGQALGAVTSLGFGPNGIPSDVSADPVMEQPGTDNFADSDSGVVTGTEVGTEGGTTAAAGINGSRARLPYGLNPATTPVLGSWRSGTQQPAVLRSAWYRLPDRDQAGPLLVVSAAGRFDQGEVEVQWATDEQAAANEPGGSITFGDVGAAPAWRNLRAPLSSIPPEATQIRLVASDDDLAPQHWIALTPPRIPELRTLQEVVGSSDPVMLDWLVGLAFPCQRPFDHRYGVVEVPKWRILPDRFGAEANSPVMDYLGGGPLGITELLLRPSSVPTYLKDDWYRDWGSLQRLTPWYPDAQPARLDLGTATRSGWWSPAPLRLS
What is the function of this protein?
Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan.
What are the official names of this protein?
Probable arabinosyltransferase C.
What is the protein family that this protein belongs to?
Belongs to the emb family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EASD_TRIVH
Sequence: MSFVSSKIFAITGGASGIGAATCRLLAKRGAATLCVGDLCSENMKLLEKDIKKINPDTKVHCTVLDVSSSSNVDEWIQDIITTFGDLHGAANIAGIAQGAGLRQAPTILEDDDQQWKKVFQVNLDGVLYSTRAQVRAMKEFSSTNPGDRSIVNVASIASMSHMPDVFAYGTSKAGCAYFTTFEVTLFALGYFSNIMGMLEGITRTPMLPRFVPSAKTQEEVEETYKKEGFSVIEADDVARTIVWLLSEDSRPVFGANINVGACMP
What is the function of this protein?
Chanoclavine-I dehydrogenase; part of the gene cluster that mediates the biosynthesis of fungal ergot alkaloid (PubMed:22403186).  DmaW catalyzes the first step of ergot alkaloid biosynthesis by condensing dimethylallyl diphosphate (DMAP) and tryptophan to form 4-dimethylallyl-L-tryptophan (PubMed:22403186).  The second step is catalyzed by the methyltransferase easF that methylates 4-dimethylallyl-L-tryptophan in the presence of S-adenosyl-L-methionine, resulting in the formation of 4-dimethylallyl-L-abrine (PubMed:22403186).  The catalase easC and the FAD-dependent oxidoreductase easE then transform 4-dimethylallyl-L-abrine to chanoclavine-I which is further oxidized by easD in the presence of NAD(+), resulting in the formation of chanoclavine-I aldehyde (PubMed:22403186).  Chanoclavine-I aldehyde is the precursor of ergoamides and ergopeptines in Clavicipitaceae, and clavine-type alcaloids such as fumiclavine in Trichocomaceae (PubMed:22403186).  However, the metabolites downstream of chanoclavine-I aldehyde in Arthrodermataceae have not been identified yet (PubMed:22403186).
What are the official names of this protein?
Chanoclavine-I dehydrogenase easD, ChaDH, Ergot alkaloid synthesis protein D.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: GUAA_CHLT3
Sequence: MNSVIVLDFGSQYTQLIARRIRELGIYSEILPYHTSAEALRERNPKALILSGGPTSVYDAFAPMPDEKIYELDIPILGICYGLQAIAKHFGGEVAASPKREFGRAQMNIVRQNELAESLLFKNIPDSTVWMSHSDKLTCLPKGFHITAQTANSELCAIEVTEGEGAHRIFGLQFHPEVHHTEFGEKLLSNFLINIAGITPDWSPQSFIDSEIARIKELVGDQTAICAISGGVDSSVAAVLVSRALGDKLHCIFVDNGLLRKNEAEKVQEKLKQLGLNLTTVDASELFLSRLKNVVSPERKRKIIGRTFIKVFEEHIHNEKFLVQGTLYPDVIESVSVKGPSQTIKTHHNVGGLPKRMKLKLIEPLRELFKDEVRKVGKLLDVPDEILTRHPFPGPGLAVRVLGSVSKERLDVLREADAIFIDELKKHDLYLQIWQAFTVLLPVQTVGVMGDNRTYENAVALRAVNSTDGMTADWARLPNDFLAHVSNRIINEVRGINRVTYDISSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: PURR_SALTY
Sequence: MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLEKQRAYLSMMAQKRVDGLLVMCSEYPEPLLSMLEEYRHIPMVVMDWGEAKADFTDTVIDNAFAGGYMAGRYLVERGHRDIGVIPGPLERNTGAGRLAGFMKAMEEALINVPDNWIVQGDFEPESGYHAMQQILSQSHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSVIGYDNVRNARYFTPALTTIHQPKDSLGETAFNMLLDRIVNKREESQSIEVHPRLVERRSVADGPFRDYRR
What is the function of this protein?
Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression.  PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.
What are the official names of this protein?
HTH-type transcriptional repressor PurR, Pur regulon repressor, Purine nucleotide synthesis repressor.
Protein: YIDD_CHLAA
Sequence: MLRWLLLKLIRFYQVAISPWTPPSCIYTPTCSHYGYEAIKKYGALRGGWMTVKRIARCHPFARGGYDPVP
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DRE2_DROWI
Sequence: MEQFKGLQKSLYIWTDNAELDKRVEQLKTATGGEVALENVHRLSFASYASSSFDLIVIECAQLTDNYVKLLHMLKPSGKLHLISFIGAAGSLLQEIKLSGFINCSEDSDNTLTAEKPGYETGSSARLSFAKKNSSTLNVWKISGDDDELIDEEDLLDEVDKQKPDPASLKVCSTTGKRKACKNCSCGLADELENEKKQENAAKQASTENAKSSCGNCYLGDAFRCSSCPYLGMPAFKPGEKVQLVDNLLKSDI
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.  Required for the maturation of extramitochondrial Fe-S proteins.  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex.  Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase.  Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit.
What are the official names of this protein?
Anamorsin homolog, Fe-S cluster assembly protein DRE2 homolog.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space.
Protein: UBACT_NITG3
Sequence: MEMTDPLRREEKKESSPDPKEESGPSRPDVSRPGRDSLLKRMKKVDPKQSEKYKQRTGQ
What is the function of this protein?
May function as a protein modifier covalently attached to lysine residues of substrate proteins.  This may serve to target the modified proteins for degradation by proteasomes.
What are the official names of this protein?
Prokaryotic ubiquitin-like protein UBact.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-like protein UBact family.
Protein: HEM1_OPSTA
Sequence: MDVIVRRCPFLARVPQAFFQQSKKSLAVYAQRCPFMMELASKPMAPSLARALCSSSSSQQKIEDTMSTGEVLKPKAEAKLPVGLATPPSNEAVAPKCPFLAAEMGQNNSNVVRQVGVEFQEDVEEIRTVQKEVSPAQLEQPSLIGKTMGEEGHQKNLMKSLLKQRPKRVSHLLQDNLPGSFTRFYYDNFFEKKIEEKKSDHTYRVFKTVNRLANEFPMADDFTGSLEDKREVSVWCSNDYLGMSRHPRVAQAIMETLRKHGSGAGGTRNISGTSKFHVELEQELADLHRKDAALLFTSCFVANDSTLFTLAKMLPGCEIYSDAGNHASMIQGIRNSGAKKFIFRHNDVAHLRELLEKGDPTKPKIVAFETVHSMDGAVCPLEEMCDLAHEFGAITFVDEVHAVGLYGPRGGGIGDRDGIMHKMDIISGTLGKAFGCVGGYIASTATLVDTVRSYAAGFIFTTSLPPMLLAGAKQSIQILKGEEGCTLRRKHQRNVKLLRQMLMDSGLPVVHCPSHIIPIRVSDAEKNTKVCDLMMSHHNIYVQAINYPTVARGDELLRIAPTPHHTPEMMKYFVDRLVQTWKEVGLELKPHSSAECTFCQQPLHFEVMNEREKSYFSGLSHLVSVCA
What is the function of this protein?
Catalyzes the pyridoxal 5'-phosphate (PLP)-dependent condensation of succinyl-CoA and glycine to form aminolevulinic acid (ALA), with CoA and CO2 as by-products.
What are the official names of this protein?
5-aminolevulinate synthase, non-specific, mitochondrial, ALAS-H, 5-aminolevulinic acid synthase 1, Delta-ALA synthase 1, Delta-aminolevulinate synthase 1.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein. Note=Localizes to the matrix side of the mitochondrion inner membrane.
Protein: CYGB1_DANRE
Sequence: MEGDGGVQLTQSPDSLTEEDVCVIQDTWKPVYAERDNAGVAVLVRFFTNFPSAKQYFEHFRELQDPAEMQQNAQLKEHGQRVLNALNTLVENLRDADKLNTIFNQMGKSHALRHKVDPVYFKILAGVILEVLVEAFPQCFSPAEVQSSWSKLMGILYWQMNRVYAEVGWENSKK
What is the function of this protein?
May have a protective function during conditions of oxidative stress.  May be involved in intracellular oxygen storage or transfer.
What are the official names of this protein?
Cytoglobin-1.
What is the protein family that this protein belongs to?
Belongs to the globin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYOE_XANC5
Sequence: MAVSARDYWDLTKPKVVALIVFTALVGMFLAIPDMPTWLQVRTGALGFLGIWLAASAAAAINQLLDAKIDAQMARTSWRPLVVGKVRPWQVLVFAGALIVISMTILVVWVNVITAVLTFASLIGYAVIYTVYLKRATSQNIVIGGLAGATPPMLGWAAVTGLPTSADWINASLLVLIIFIWTPPHFWALAIFRRADYAKAAIPMLPVTHGVPHTRKQILVYTVLLAIVTLAPVAVGMSGVFYLGGAIVLNAVFLWYAWRMLNPPDELFSMKMFGYSIVYLMALFAFLMVDHLLLPWVR
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUDC_SHIB3
Sequence: MDRIIEKLDHGWWVVSHEQKLWLPKGELPYGEAANFDLVGQRALQIGEWQGEPVWLVQQQRRHDMGSVRQVIDLDVVLFQLAGRGVQLAEFYRSHKYCGYCGHEMYPSKTEWAMLCSHCRERYYPQIAPCIIVAIRRDDSILLAQHTRHRNGVHTVLAGFVEVGETLEQAVAREVMEESGIKVKNLRYVTSQPWPFPQSLMTAFMAEYDSGDIVIDPKELLEANWYRYDDLPLLPPPGTVARRLIEDTVAMCRAEYE
What is the function of this protein?
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.  The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing.  Has preference for mRNAs with a 5'-end purine.  Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.
What are the official names of this protein?
NAD-capped RNA hydrolase NudC, DeNADding enzyme NudC, NADH pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudC subfamily.
Protein: RLMKL_SHEB9
Sequence: MLNFFAAAPKGFEYSLAQELTEFGATEVKESVAGVYFTASLALAYRITLWTRLASRIVLVIYKGSCESAEQLYNAAYCVDWPAHFSNKSTFSIDFHGTGGFLNNTQFGALKIKDAIVDRFRDDDIERPNVSRVDAEFKVDAHFRNGVITIAMNFSGPSLHQRGYRSTTGEAPLKENLAANMLVRSGWQASPSTLLDPFCGSGTVLIEAALMAADIAPGLQRSRFGFEHWRRHDKAVWQEIVEEAKARASLGVKRCEIKFYGSDIDSRLVALAKRNAENAGVLELIEFKVADALTIAPPAESGYLITNPPYGERLGNVSELLQLYYQLGDKFKKEFGGWKVAMLCSDIELVSSLKLKADKQMKMFNGALECAFNIYTLHANSTRRDTPVLPDGVDIADIAPAFANRIKKNAKLLEKWAKKEGIDSYRIYDADIPEYNVAVDKYLDYVIIQEYMAPATIPEAVTKRRLSDVLLALPSAIGINPNKMIMKTRERQKGTSQYQKLDERKLELITTEYGAKFKLNLTGYLDTGLFLDHRLTRRLVGQKSKGRRVLNLFSYTGSASVHAALGGAKSVTTVDMSNTYIAWAKDNFALNGLQGKQYEFVQSDCMQWIRDCNEQYDLIFIDPPTFSNSKRMEDSFDVQRDHVNLLASLVKLLSPTGELVFSNNKRKFKMDIETLTKMNINVTNIDDVTLPMDYKRNPHIHNTWLITHA
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURD_FRAT1
Sequence: MFSFYFNDNKITKLLMVGYGSTGKSVCDFLANFIDITVDISQNDDEFVNYDLNSYDLITVSPGIPLNKSPYRALTKFKDKIVSDIDIFYQYIKDTKAKTIAVTGSNGKSTVVTMTDFVLKDLGYKSILVGNIGTPALNKIGEKFDYCVVEVSSFQINLFNCVRFDLGCIINVSPDHLDRYQNFEQYKQSKLNLAKFSNDFFVYDVHNGIKYAGEYQIIRGAIYRNSTKLLDIVETKLFGEHNLENIIVVLNILDRLGLDINQAIDSIKKFKGLEHRCKIVKKVNSTTYINDSKGTNVGATIAALNSITNSKNIILLLGGVAKGGDFSLMIKSLDKYVKYVYIYGADKEYIESYIKGYCKYQLCNNMKQAFELSSQKANSNEIVLLSPACASFDEFSGYAQRGEVFQNLVAQLEQKS
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXC_SYNAS
Sequence: MYFQRTLKSDLSCQSVGLHSGRKVNMRIRPASSDEGIILVRTDTRYRQMIRVCLENVTDTTLATTIGSSGAAISTVEHILSALSGMGVDNAIIEVDAPEIPIMDGSALPFVNMLKLVGIRTQEKLKKYLVVKKPVSVSEGESFAMLAPSSSFEITYKIEFDHPLIKEQSYHLKLSDETYEKEICSSRTFGFLKDVEYLQAKGLALGGSLKNAVILDEKRIINKEGLRSHNEFVKHKILDAIGDLSLIGMPIVGHFIAYKSGHKLNSMLVKALLEQQENWTTASFLNCQDAHGQNTREKFSIRDIPARKILGAIHA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: ENO_IDILO
Sequence: MSKIVKVVGREIMDSRGNPTVEADVYLESGHMGRAAAPSGASTGSREALELRDGDTSRYLGKGVETAVANINGAIAEALSGIDAINQEAVDNIMLRLDGTDNKEKLGANAILAVSLAVAKAAALSKGIELYEHIANLNNTSGKYSMPLPMMNILNGGEHADNNVDIQEFMIQPVGAESFKEGLRMGAEVFHALKKVLQKRGLSTAVGDEGGFAPNLASNEEALQVIVEAVENAGYKMGSDITLALDCAASEFYRDGKYELSGEGKSFTAEEFADYLAELCDRYPIISIEDGLDESDWDGWKVLTEKLGSKVQLVGDDLFVTNTRILKEGIDKSIANSILIKFNQIGSLTETLAAIAMAREAGYSAVISHRSGETEDATIADLAVGTAAGQIKTGSLCRSDRVAKYNQLLRIEGDLNGQAPYRGRQEVNAG
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RL34_WIGBR
Sequence: MKRTFQPSLLKRKKNHGFRLRMATKSGRKILSHRRRKNRCKLTVSDK
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: RS5_SHESM
Sequence: MAKLEAQQKDDLQEKLIAVNRVSKVVKGGRIFSFTALTVVGDGNGKVGYGYGKAREVPAAIQKAMEKARRNMVTVELNAGTLHHPVKGRHTGSRVYMQPASQGTGIIAGGAMRAVLEVAGVHNVLSKAYGSTNPINIVRATVDALVHMKSPSQIAAKRGLNVDEIRG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.