PharMolix/UniProtQA huggingface dataset:
Protein: POL_SMRVH
Sequence: MGQASSHSENDLFISHLKESLKVRRIRVRKKDLVSFFSFIFKTCPWFPQEGSIDSRVWGRVGDCLNDYYRVFGPETIPITTFNYYNLIRDVLTNQSDSPDIQRLCKEGHKILISHSRPPSRQAPVTITTSEKASSRPPSRAPSTCPSVAIDIGSHDTGQSSLYPNLATLTDPPIQSPHSRAHTPPQHLPLLANSKTLHNSGSQDDQLNPADQADLEEAAAQYNNPDWPQLTNTPALPPFRPPSYVSTAVPPVAVAAPVLHAPTSGVPGSPTAPNLPGVALAKPSGPIDETVSLLDGVKTLVTKLSDLALLPPAGVMAFPVTRSQGQVSSNTTGRASPHPDTHTIPEEEEADSGESDSEDDEEESSEPTEPTYTHSYKRLNLKTIEKIKTAVANYGPTAPFTVALVESLSERWLTPSDWFFLSRAALSGGDNILWKSEYEDISKQFAERTRVRPPPKDGPLKIPGASPYQNNDKQAQFPPGLLTQIQSAGLKAWKRLPQKGAATTSLAKIRQGPDESYSDFVSRLQETADRLFGSGESESSFVKHLAYENANPACQSAIRPFRQKELSTMSPLLWYCSAHAVGLAIGAALQNLAPAQLLEPRPAFAIIVTNPAIFQETAPKKIQPPTQLPTQPNAPQASLIKNLGPTTKCPRCKKGFHWASECRSRLDINGQPIIKQGNLEQGPAPGPHYRDELRGFTVHPPIPPANPCPPSNQPRRYVTDLWRATAGSAGLDLCTTTDTILTTQNSPLTLPVGIYGPLPPQTFGLILAEPALPSKGIQVLPGILDNDFEGEIHIILSTTKDLVTIPKGTRLAQIVILPLQQINSNFHKPYRGASAPGSSDVYWVQQISQQRPTLKLKLNGKLFSGILDTGADATVISYTHWPRNWPLTTVATHLRGIGQATNPQQSAQMLKWEDSEGNNGHITPYVLPNLPVNLWGRDILSQMKLVMCSPNDTVMTQMLSQGYLPGQGLGKNNQGITQPITITPKKDKTGLGFHQNLPRSRAIDIPVPHADKISWKITDPVWVDQWPLTYEKTLAAIALVQEQLAAGHIEPTNSPWNTPIFIIKKKSGSWRLLQDLRAVNKVMVPMGALQPGLPSPVAIPLNYHKIVIDLKDCFFTIPLHPEDRPYFAFSVPQINFQSPMPRYQWKVLPQGMANSPTLCQKFVAAAIAPVRSQWPEAYILHYMDDILLACDSAEAAKACYAHIISCLTSYGLKIAPDKVQVSEPFSYLGFELHHQQVFTPRVCLKTDHLKTLNDFQKLLGDIQWLRPYLKLPTSALVPLNNILKGDPNPLSVRALTPEAKQSLALINKAIQNQSVQQISYNLPLVLLLLPTPHTPTAVFWQPNGTDPTKNGSPLLWLHLPASPSKVLLTYPSLLAMLIIKGRYTGRQLFGRDPHSIIIPYTQDQLTWLLQTSDEWAIALSSFTGDIDNHYPSDPVIQFAKLHQFIFPKITKCAPIPQATLVFTDGSSNGIAAYVIDNQPISIKSPYLSAQLVELYAILQVFTVLAHQPFNLYTDSAYIAQSVPLLETVPFIKSSTNATPLFSKLQQLILNRQHPFFIGHLRAHLNLPGPLAEGNALADAATQIFPIISDPIHEATQAHTLHHLNAHTLRLLYKITREQARDIVKACKQCVVATPVPHLGVNPRGLVPNAIWQMDVTHFTPFGKQRFVHVTVDTFSGFILATPQTGEASKNVISHVIHCLATIGKPHTIKTDNGPGYTGKNFQDFCQKLQIKHVTGIPYNPQGQGVVERAHQTLKNALNRLARSPLGFSMQQPRNLLSHALFQLNFLQLDSQGRSAADRLWHPQTSQQHATVMWRDPLTSVWKGPDPVLIWGRGSACIYDQKEDGPRWLPERLIRHINNQTAPLCDRPSNPNTAPGPKGSP
What is the function of this protein?
Catalyzes viral DNA integration into the host chromosome, by performing a series of DNA cutting and joining reactions.
What are the official names of this protein?
Gag-Pro-Pol polyprotein.
What are the subcellular locations of this protein?
[Capsid protein p35]: Virion. SUBCELLULAR LOCATION: [Matrix protein p19]: Virion. SUBCELLULAR LOCATION: [Probable nucleocapsid protein-dUTPase]: Virion. SUBCELLULAR LOCATION: [Protease 13 kDa]: Virion. SUBCELLULAR LOCATION: [Protease 17 kDa]: Virion.
Protein: HV373_HUMAN
Sequence: MEFGLSWVFLVAILKGVQCEVQLVESGGGLVQPGGSLKLSCAASGFTFSGSAMHWVRQASGKGLEWVGRIRSKANSYATAYAASVKGRFTISRDDSKNTAYLQMNSLKTEDTAVYYCTR
What is the function of this protein?
V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170).
What are the official names of this protein?
Immunoglobulin heavy variable 3-73.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: MT1A_BOVIN
Sequence: MDPNCSCPTGGSCSCAGSCTCKACRCPSCKKSCCSCCPVGCAKCAQGCVCKGASDKCSCCA
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.
What are the official names of this protein?
Metallothionein-1A, MT-1A, MTC, Metallothionein-IA, MT-IA.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 1 family.
Protein: RPOB_NEORS
Sequence: MSEFHRLYFDELLFDFPDLVKVQKDSYASFVGGGDAVSSINDIFASVFPVNDGYGRASLEFVSCRMGEPKHDEYGCVERGITYSAPLRAILRLVVFGDETSGEGGEGVSTEPAVKDVREQEIYMGDIPIMSKNGTFIINGVERVVVSQMHRAPGVFFDNDKARSISGKLNYIARIIPYRGSWLDFEFDAKDVLYFRIDKKRKLPVTLLLRALGLSNKDIFAQFCEVSECRLTKDGKWTVCFVPERFKGVRLQYDLINAETGELVLAKGNRISIVLARNLYAKGLRYCYMDLEVMKDMYLADDLVSAKGEVLLPHGTRLTKEHVAKLEFLDVDSIKLVELKGNYIFSTVLQYDCSYEEAMLSIYRVIRPGEIPSIESAEKLFESLFFSPERYDLLNVGRIRLNAKFNLSHDESLTVLTKEDIFCTVRELALLQREVGDVDDIDHLGNSALGLRRVRSVGEFMDNQFRIGLVRMAKVIVENMATADFDTVMPCEMINSKILGAVIREFFMSSALSQFMDQTNPLSEITHKRRISALGPGGLNRGRAGFEVRDVHTTHYGRICATETPEGATIGLINSLAIYAKINKYGFIETPYRYVRDGRVTDEVTYLSAIDEIKANICQASVRVDEEGYILDDLVYCRRNYENVFIPRSEVQFADVSAKQIVSVAASLIPFLENDDANRALMGSNMQRQAVPLIVPEAPLVGTGMEGYVARGSGAVIVAKRAGIVQYIDARNIVVASESKDDFWIDSYTLCKFRKSNHNTCIHQRCVVYQGQRVKKGDILADGPAIQQGELALGRNLVVAFLSWRGYNFEDSVVISSNVVRDDLFTSVHLEGFECVVRDTRLGPEEITRDVSGVAEEFLHCLDEFGIACVGANVEAGDVLVGKVTPKSSSPVTPEEKLLRAIFGEKAIDVKDSSLYLPPGVSGCVVDVKVLQRRGIEKVGRALLIEKQAIDAEKARRDHELAVLTNYIYSLLKEMLVGKVALNTLAPISKGDLITGEALEKIDRESWWKLSVDEISSIKLLRQRFVDRFDEINKTYEENFEKIRGDDDLAQGVLMVVKVFVAVKHTLQPGDKMSGRHGNKGVISRIVPAEDMPYLADGTPVDIILNPLGVPSRMNVGQILETHLGWAAYNLGKKISKLLDEGNYSEVKSLILEIYKNDRKMMARLKRMTDTEIVEYSRSLRRGVPVAASVFEGPKTDEIERLLVLAGKDPSGQEVLYDGVTGEKFDRKVTVGCKYMLKLHHLVNDKIHARSIGSYSLITQQPLGGKSHFGGQRFGEMECWALQAYGATFALQEMLTIKSDDVVGRVNVYDSIVRGDNDFYYGVPESFNVMMNELRALCLNVEFCSDLERKEDFSDLPLAVSGR
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: IF172_MOUSE
Sequence: MQLKHLRTLLSPQDGAAKVTCMAWSQNNAKFAVCTVDRVVLLYDEHGERRDKFSTKPADMKYGRKSYMVKGMAFSPDSTKIAIGQTDNIIYVYKIGEDWGDKKVICNKFIQTSAVTCLQWPAEYVIVFGLAEGKVRLANTKTNKSSTIYGTESYVVALTTNCSGKGILSGHADGTIVRYFFDDEGSGESQGKLVNHPCPPYALAWATNSIVAAGCDRRIVAYGKEGHVLQTFDYSRDPQEREFTTAAASPGGQSVVLGSYDRLRVFNWSPRRSIWEEAKPKEIANLYTVTALAWKRDGSRLCAGTLCGGVEQFDCCLRRSIYKNKFELTYVGPSQVIVKNLSSGTRVVLKSHYGYEVEEVKILGKERYLVAHTSDTLLLGDLNTNRLSEIAWQGSGGNEKYFFENENVCMIFNAGELTLVEYGSNDSLGSVRTEFMNPHLISVRINERCQRGMEDNKKLAYLVDIKTIAIVDLIGGYNIGTISHESRVDWLELNETGHKLLFRDRKLRLHLYDIESCSKTMILNFCSYVQWVPGSDVLVAQNRNSLCVWYNIEAPERVTMSSIRGDVVGLERGGGKTEVMVTEGVTTVAYTLDEGLIEFGTAIDDGNYTRATAFLETLEMTPETEAMWKTLSKLALEARQLHTAERCFSALGHVAKARFLHETNEIADQVSREYGGEGTDFYQVRARLAMLEKNYKLAEMIFLEQNAVEEAMDMYQELHRWEECIAVAEAKGHPALEKLRRDYYQWLMDTQQEERAGELQESQGDGLAAISLYLKAGLPAKAARLVLTREELLANTELVEHITTALIKGELYERAGDLFEKIRNPQRALECYCKGNAFMKAVELARLAFPVEVVRLEEAWGDHLVQQKQLDAAINHYIEARCSIKAIEAALGARQWKKAIYILDLQDRNTASKYYPRVAQHYASLQEYEIAEELYTKGDRTKDAIDMYTQAGRWEQAHKLAMKCMRPEDVSVLYITQAQEMEKQGKYREAERLYVTVEEPDLAITMFKKHKLYDDMIRLVGKHHPDLLSDTHLHLGKELEAEGRLQEAEYHYLEAQEWKATVNMYRSSGLWEEAYRVAKAHGGANAHKHVAYLWAKSLGGEAAVRLLNKLGLLEATIDHAADNCSFEFAFELSRLAFKHKAPEIHLKYAMYLEDEGKFEEAEAEFIRAGKPKEAVLMFVHNQDWEAAQRVAEAHDPDSVAEVLVGQARGALEEKDFQKAEGLLLRAQRPGLALNYYKEAGLWSDALRICKDYVPGQLEALQEEYEREATKKGGRGVEGLVEQARQWEQAGEYSRAVDCYLKVRDSGSSGLMEKCWMKAAELSIKFLPPQRSLEVVRVVGPQLIGIGKHSAAAELYLNLDLVKEAIDAFIEGEEWNKAKRVAKELDPRYEDYVDQHYKEFLKNQGKVDSLVGVDVVAALDLYVEQGQWDKCIETATKQNYKILHKYVALYATHLIREGGYAQALALYVQHGAPANPQNFNIYKRIFTDMVSSPGTNNAEAYHSWADLRDVLFNLCENLVKSSEANSAAHEEFEMMLLISHYYATRSAAQSIKQLETVAARLSVSLLRHTQLLPADKAFYEAGTAAKEVGWENMAFIFLNRFLDLTDAIEEGTLDALDHSDFQDTDIPFEVPLPAKQHVPEAQREEVRDWVLTVSMDQRLEQVLPRDERGVYEASLVAASTGVRALPCLITGYPILRNKIEFKRPGKAANKDNWNKFLMAIKTSHSPVCQDVLKFISQWCGGLPSTSFSFQ
What is the function of this protein?
Required for the maintenance and formation of cilia.  Plays an indirect role in hedgehog (Hh) signaling, cilia being required for all activity of the hedgehog pathway.
What are the official names of this protein?
Intraflagellar transport protein 172 homolog, Protein wimple.
What is the protein family that this protein belongs to?
Belongs to the IFT172 family.
What are the subcellular locations of this protein?
Cell projection, cilium.
Protein: LCL2_VERA1
Sequence: MRALTSLSVVLLALISTVSAQFGFFEQMFGGQQQGQQQRPQNVPSDSAAYRQQYDRSYCEHYLCPDTLACVHYPHHCPCPWPMNEDKFELSEGQRICVSKGGFAANEAARKVELARKGLL
What is the function of this protein?
Probable component of the endoplasmic reticulum-associated degradation (ERAD) pathway.
What are the official names of this protein?
Long chronological lifespan protein 2.
What is the protein family that this protein belongs to?
Belongs to the LCL2 family.
Protein: ARNE_SHIDS
Sequence: MIWLTLVFASLLSVAGQLCQKQATCFVAINKRRKHIVLWLGLALACLGLAMVLWLLVLQNVPVGIAYPMLNLNFVWVTLAAVKLWHEPVSPRHWCGVAFIIGGIVILGSTV
What is the function of this protein?
Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
What are the official names of this protein?
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE, L-Ara4N-phosphoundecaprenol flippase subunit ArnE, Undecaprenyl phosphate-aminoarabinose flippase subunit ArnE.
What is the protein family that this protein belongs to?
Belongs to the ArnE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS24_IGNH4
Sequence: MSEFEVQVVNKRWNPLAEREELDLVLVHVAKPTPSRCEVEEKVAQMLGVDKKLVVVTKLLSEYGIGRTRARAHVYKNYERLQKLEPEKVKKLHEQCSQAQEAQAQ
What are the official names of this protein?
30S ribosomal protein S24e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS24 family.
Protein: DURA_STRGV
Sequence: CKQSCSFGPFTFVCDGNTK
What is the function of this protein?
Is a potent inhibitor of human phospholipase A2.
What are the official names of this protein?
Lantibiotic duramycin, Antibiotic PA48009, Leucopeptin.
What is the protein family that this protein belongs to?
Belongs to the type B lantibiotic family.
What are the subcellular locations of this protein?
Secreted.
Protein: SPAN2_BPKMV
Sequence: MPPCSATSRRSLPGPTPSARRWTVPWTRTARGLTGLCLLLSLTACATAPAPAVLCEHPLIDPTTQAGLIRAVAAYQDALDLCNALNQGD
What is the function of this protein?
Component of the spanin complex that disrupts the host outer membrane and participates in cell lysis during virus exit.  The spanin complex conducts the final step in host lysis by disrupting the outer membrane after holin and endolysin action have permeabilized the inner membrane and degraded the host peptidoglycans.  Host outer membrane disruption is possibly due to local fusion between the inner and outer membrane performed by the spanin complex (By similarity).
What are the official names of this protein?
Probable spanin, outer lipoprotein subunit.
What are the subcellular locations of this protein?
Host cell outer membrane; Lipid- anchor; Periplasmic side.
Protein: MNTH_BRUSU
Sequence: MVPHGSCPSGAREVTFEGWRRERGEASMSDVHRTIRVNRSGSKFRRALSFFGPGYLVAVGYMDPGNWATSLAGGSRFGYALLSVVLLSNLMAVLLQALCTRLAVATGRDLAQACRDAYPRFLAWPLWLLAELAICATDLAEVIGTAIGLNLLFGIPLEIGVILTAVDVLLVLYLQNKGFRRVEALIITLLGVIALCFLTQIIMAQPQWGEVIKGFAPTTEIVSNPDMLYIALGIIGATVMPHNLYLHSGIVQTRDYGHTTAEKREAIRYATLDSTIALTFALVINASILILAAASFHATGHTGVEDLDKAHALLNPLLGSAIAPALFAIALLCCGLNSTITATMAGQIVMEGFIDIRLKPWIRRAITRFVAIVPAAIVTILYGSQGTTELLILSQVVLSLQLPFAVIPLVIFTAQKKKMGSLAAAPWVTFLAAITAAIIVVLNLKLIYDFFTGAPI
What is the function of this protein?
H(+)-stimulated, divalent metal cation uptake system.
What are the official names of this protein?
Divalent metal cation transporter MntH.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL35_BRASB
Sequence: MPKLKTKSGAKKRFKVTATGKVMHAQRGKRHGMIKRTKKQIRQLRGTRVLFKTDGDNVKKYFLPNA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: MCH_METS3
Sequence: MVSVNLEAKKTVDVMIEKQDELNIAVSQLSNGATIIDCGVNVDGSFKAGELYTKVCLGGLADVGISIPGDLSEKFALPSVKIKTDSPAISTLGSQKAGWSVSVGDFFALGSGPARAICKKPAETYEEIGYEDTEADLAILTLEADVLPGEDVAQYIADECNVDVKDVYLLVAPTSSLVGSIQISGRVVENGTYKMLEAIKFDVTKVKHAAGIAPIAPIDPDGLKAMGKTNDAVLFGGRTYYYVESDENDDIADVAAKLPSSAADGYGKPFFDVFKEAEFDFYKIDKGMFAPAEVVINDLTTGKIYKEGYVNVDLLKKSFGVDN
What is the function of this protein?
Catalyzes the reversible interconversion of 5-formyl-H(4)MPT to methenyl-H(4)MPT(+).
What are the official names of this protein?
Methenyltetrahydromethanopterin cyclohydrolase, Methenyl-H4MPT cyclohydrolase.
What is the protein family that this protein belongs to?
Belongs to the MCH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYSY_RHOP2
Sequence: MIPYHDLLERILSDGAEKHDRTGTGTLSVFGHQLRFDLAAGFPMLTTKRLPLKAIIHELLWFLQGDTNIKYLHDHGVTIWDEWADANGDLGPVYGAQWRSWPTADGRSIDQIAHVVDMIRRNPDSRRLIVTAWNPADVEKMALPPCHCLFQFYVANGRLSCQLYQRSADVFLGVPFNIASYALLTMMVAQVTGLKPGDFIHTLGDAHLYSNHLEQARLQLTRAPRALPAMAINPAVTDIFGFRYEDFTLHGYDPHPHIKAEVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_RAT
Sequence: MAQDQGEKENPMRELRIRKLCLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEILEKGLKVREYELRKNNFSDTGNFGFGIQEHIDLGIKYDPSIGIYGLDFYVVLGRPGFSIADKKRRTGCIGAKHRISKEEAMRWFQQKYDGIILPGK
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.  As part of the 5S RNP/5S ribonucleoprotein particle it is an essential component of the LSU, required for its formation and the maturation of rRNAs.  It also couples ribosome biogenesis to p53/TP53 activation.  As part of the 5S RNP it accumulates in the nucleoplasm and inhibits MDM2, when ribosome biogenesis is perturbed, mediating the stabilization and the activation of TP53.  Promotes nucleolar location of PML.
What are the official names of this protein?
60S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: CP141_MYCTU
Sequence: MTSTSIPTFPFDRPVPTEPSPMLSELRNSCPVAPIELPSGHTAWLVTRFDDVKGVLSDKRFSCRAAAHPSSPPFVPFVQLCPSLLSIDGPQHTAARRLLAQGLNPGFIARMRPVVQQIVDNALDDLAAAEPPVDFQEIVSVPIGEQLMAKLLGVEPKTVHELAAHVDAAMSVCEIGDEEVSRRWSALCTMVIDILHRKLAEPGDDLLSTIAQANRQQSTMTDEQVVGMLLTVVIGGVDTPIAVITNGLASLLHHRDQYERLVEDPGRVARAVEEIVRFNPATEIEHLRVVTEDVVIAGTALSAGSPAFTSITSANRDSDQFLDPDEFDVERNPNEHIAFGYGPHACPASAYSRMCLTTFFTSLTQRFPQLQLARPFEDLERRGKGLHSVGIKELLVTWPT
What are the official names of this protein?
Putative cytochrome P450 141.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DBP8_YEAS7
Sequence: MADFKSLGLSKWLTESLRAMKITQPTAIQKACIPKILEGRDCIGGAKTGSGKTIAFAGPMLTKWSEDPSGMFGVVLTPTRELAMQIAEQFTALGSSMNIRVSVIVGGESIVQQALDLQRKPHFIIATPGRLAHHIMSSGDDTVGGLMRAKYLVLDEADILLTSTFADHLATCISALPPKDKRQTLLFTATITDQVKSLQNAPVQKGKPPLFAYQVESVDNVAIPSTLKIEYILVPEHVKEAYLYQLLTCEEYENKTAIIFVNRTMTAEILRRTLKQLEVRVASLHSQMPQQERTNSLHRFRANAARILIATDVASRGLDIPTVELVVNYDIPSDPDVFIHRSGRTARAGRIGDAISFVTQRDVSRIQAIEDRINKKMTETNKVHDTAVIRKALTKVTKAKRESLMAMQKENFGERKRQQKKKQNDGKSLRS
What is the function of this protein?
ATP-binding RNA helicase involved in 40S ribosomal subunit biogenesis and is required for the normal formation of 18S rRNAs through pre-rRNA processing at A0, A1 and A2 sites.  Required for vegetative growth (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase DBP8, DEAD box protein 8.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: TSSP_MOUSE
Sequence: MAVKAPWLGFLLLVSLWGLSTPALLLRRLREHIQKFQESSSLHPGFGLGHGPGAVPKQGWLEQPLDPFNASDRRTFLQRYWVNDQHRTGQDVPVFLHIGGEGSLGPGSVMAGHPAALAPAWGALVISLEHRFYGLSMPAGGLDLALLRYLSSRHALADVASARQALSGLLNVSSSSPWICFGGSYAGSLATWARLKFPHLVFAAVASSAPLSAVVDFSAYNQVVARSLTQVAIGGSLECLAAASTAFTEVERLLRAGPAAQAVLREELGACGSLDLTEDQAELLGALQALVGGTVQYDGQAGAPLSVRQLCGLLLGKWGNRSRSTPYLGLRRAVQIVLRSMGQKCLSFSRAETVAQLSNTEPQVSGVGDRQWLYQTCTEFGFYVTCEGLQCPFSQLPALPFQLELCEQVFGLSPASVAQAVAQTNSYYGGQSPGATQVLFVNGDTDPWHVLSVTQDLGLSEPALLIPSASHCFDMAPMRPSDSPSLRLGRQKISQQLQDWLKDIKKSQS
What is the function of this protein?
Protease that may play a role in T-cell development.
What are the official names of this protein?
Thymus-specific serine protease, Serine protease 16.
What is the protein family that this protein belongs to?
Belongs to the peptidase S28 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle. Note=Vesicular, either lysosomal or endosomal.
Protein: HTPX_CHLPD
Sequence: MKRVVLFLFTNLAVMLVLSVSARVLGVDRFLTGNGLDMGMLLLFAALIGFGGSFISLLMSKTMAKWSTGARVIQQPANQNEVWLVDTVSQLSKKAGLAMPEVAIYDGAPNAFATGPSKSRSLVAVSTGLLQSMDRKQVEAVLAHEVAHIDNGDMVTLTLIQGVLNTFVIFLSRVIAYAIDSFLRSDDDESGSPGIGYWISSIIFEIMFGILASVVVMYFSRKREYRADAGAAVLLGDRRPMIDALRALGGLQAGQLPKEMAASGIAGGGMMALFSSHPPLESRIAALESAR
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLI2_MOUSE
Sequence: METSAPAPALEKKEAKSGLLEDSSFPDPGKKACPLAVAAAVAAHGVPQQLLPAFHAPLPIDMRHQEGRYHYDPHSVHSVHGPPTLSGSPVISDISLIRLSPHPAGPGESPFSAHHPYVNPHMEHYLRSVHSSPTLSMISAARGLSPADVAHEHLKERGLFSLAAPGTNPSDYYHQMTLMASHPTPYGDLLMQSGGAASAPHLHDYLNPVDASRFSSPRVTPRLSRKRALSISPLSDASLDLQRMIRTSPNSLVAYINNSRSSSAASGSYGHLSAGALSPAFTFPHPINPVAYQQILSQQRGLGSAFGHTPPLIQPSPTFLAQQPMTLTSISTMPTQLSSSSSNCLNDANQNKQNSESAVSSTVNPITIHKRSKVKTEAEGLRPASPLGLTQEQLADLKEDLDRDDCKQEAEVVIYETNCHWADCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQRNDVHVRAPLLKENGDNEASAEPGGRGPEESVEASSTSHTVEDCLHIKAIKTESSGLCQSSPGAQSSCSSEPSPLGSAPNNDSGMEMPGTGPGSLGDLTALADTCPGADTSALAAPSTGGLQLRKHMSTVHRFEQLKREKLKSLKDSCSWAGPAPHTRNTKLPPLPVNGSVLENFNNTGGGGPAGLLPSQRLPELTEVTMLSQLQERRDSSTSTMSSAYTVSRRSSGISPYFSSRRSSEASPLGGLRPHNASSADSYDPISTDASRRSSEASQCSGGGPGLLNLTPAQQYNLRAKYAAATGGPPPTPLPGLDRVSLRTRLALLDAPERALPGACPHPLGPRRGSDGPTYSHGHGHGYAGAAPAFPHEGPNSSTRRASDPVRRPDPLILPRVQRFHSTHNMNPGSLPPCADRRGLHVQSHPSVDSNLTRNAYSPRPPSINENVVMEAVAAGVDGPGLECDLGLVEDELVLPDDVVQYIKAHTGGTLDDGIRQGYPTEGTGFPENSKLPSPGLQGHRRLAAADSNMGPSAPGLGGCQLSYSPSSNLNKSNMPVQWNEVSSGTVDALPTQVKPPPFPHSNLAVVQQKPAFGQYPGYNPQSVQSSSGGLDSTQPHLQLRGAPSASRGSYTQQPRQPAAGSQCLGMSAAMSPQASYSQAHPQLSPNIVSGSLNQFSPSCSNMAAKPSHLGLPQQMEVVPNATIMNGHQREHGVPNSSLAAVSQPHPVLSYPQQDSYQQGSNLLSSHQPGFMESQQNAGFGLMQPRPPLEPNTASRHRGVRSGQQQLYARTTGQAMVTSANQETAEAMPKGPAGTMVSLAPQPSQDTGRAQDQNTLYYYGQIHMYEQNGGCPAVQPQPPQPQACSDSIQPEPLPSPGVNQVSSTVDSQLLEPPQIDFDAIMDDGDHSSLFSGALSPTLLHNLSQNSSRLTTPRNSLTLPSIPAGISNMAVGDMSSMLTSLAEESKFLNMMT
What is the function of this protein?
Functions as transcription regulator in the hedgehog (Hh) pathway (PubMed:9006072).  Functions as transcriptional activator (PubMed:10806483).  May also function as transcriptional repressor (PubMed:10433919).  Requires STK36 for full transcriptional activator activity (PubMed:10806483).  Binds to the DNA sequence 5'-GAACCACCCA-3' which is part of the TRE-2S regulatory element (By similarity).  Is involved in the smoothened (SHH) signaling pathway (PubMed:10433919).  Required for normal skeleton development (PubMed:9006072).
What are the official names of this protein?
Zinc finger protein GLI2, Tax helper protein.
What is the protein family that this protein belongs to?
Belongs to the GLI C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell projection, cilium. Note=STK36 promotes translocation to the nucleus (PubMed:10806483). In keratinocytes, it is sequestered in the cytoplasm by SUFU. In the absence of SUFU, it translocates to the nucleus (PubMed:23034632).
Protein: GLTB_ORYSJ
Sequence: MATLPRAAAAAAPSPAAALLPLPRAAPLLAGRAAARSAARRLRARGTRAPPLAAARRGWGGVSPRAVLDLPRRREAAEKPAQKAADLNEILSERGACGVGFVANLKNEPSFNIVRDALVALGCMEHRGGCGADNDSGDGSGLMSGIPWDLFNDWANKQGLAPLDRTNTGVGMVFLPQDENSMEEAKAVVAKVFTDEGLEVLGWRTVPFNVSVVGRYAKETMPNIQQIFVKVAKEDNADDIERELYICRKLIERATKSASWADELYFCSLSSRTIVYKGMLRSEILGQFYLDLQNELYKSPFAIYHRRYSTNTSPRWPLAQPMRLLGHNGEINTIQGNLNWMRSREATLQSPVWRGREHEIRPFGDPKASDSANLDSTAELLLRSGRSPAEAMMILVPEAYKNHPTLSIKYPEVIDFYDYYKGQMEAWDGPALLLFSDGRTVGACLDRNGLRPARYWRTSDDFVYVASEVGVIPMDESKVVMKGRLGPGMMITVDLQTGQVLENTEVKKSVASANPYGSWLQQSTRSIKPVNFQSSVAMDNETVLRHQQAFGYSSEDVQMVIETMASQGKEPTFCMGDDIPLAVLSQKPHMLFDYFKQRFAQVTNPAIDPLREGLVMSLEVNIGKRRNILEVGPENADQVTLSSPVLNEGELESLLNDSKLKPKVLSTYFDIRKGLDGSLDKAIKVLCDEADAAVRNGSQLLVLSDRSEALEPTRPAIPILLAVGAIHQHLIQNGLRMSASIVADTAQCFSTHQFACLIGYGASAICPYLALETCRQWRLSNKTVNLMRNGKMPTVTIEQAQRNFIKAVKSGLLKILSKMGISLLSSYCGAQIFEIYGLGQEVVDLAFCGSVSKIGGLTLDELGRETLSFWVKAFSEDTAKRLENFGFIQSRPGGEYHANNPEMSKLLHKAVREKSDNAYTVYQQHLASRPVNVLRDLLELKSDRAPIPIGKVEPATSIVERFCTGGMSLGAISRETHEAIAIAMNRIGGKSNSGEGGEDPIRWSPLADVEDGYSPTLPHLKGLQNGDTATSAIKQVASGRFGVTPTFLVNAEQIEIKIAQGAKPGEGGQLPGKKVSAYIARLRNSKPGVPLISPPPHHDIYSIEDLAQLIYDLHQINPKAKVSVKLVAEAGIGTVASGVSKGNADIIQISGHDGGTGASPISSIKHAGGPWELGLSETHQTLIQNGLRERVVLRVDGGFRSGLDVLMAAAMGADEYGFGSVAMIATGCVMARICHTNNCPVGVASQREELRARFPGVPGDLVNYFLFVAEEVRATLAQLGFEKLDDIIGRTDILKAKHVSLAKTQHIDLKYLLSSAGLPKWSSSQIRSQDVHSNGPVLDETILADPDISDAIENEKEVSKTFQIYNVDRAVCGRVAGVIAKKYGDTGFAGQLNITFTGSAGQSFGCFLTPGMNIRLVGEANDYVGKGMAGGELVVVPVEKTGFVPEDAAIVGNTCLYGATGGQVFVRGKTGERFAVRNSLGQAVVEGTGDHCCEYMTGGCVVVLGKVGRNVAAGMTGGLAYILDEDDTLVPKVNKEIVKMQRVNAPAGQMQLKGLIEAYVEKTGSEKGATILREWEAYLPLFWQLVPPSEEDSPEACAEFERVLAKQATTVQSAK
What is the function of this protein?
Involved in glutamate biosynthesis in leaf.  Required for the reassimilation of ammonium ions generated during photorespiration (By similarity).
What are the official names of this protein?
Ferredoxin-dependent glutamate synthase, chloroplastic, Fd-GOGAT.
What is the protein family that this protein belongs to?
Belongs to the glutamate synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.