PharMolix/UniProtQA huggingface dataset:
Protein: KLF10_HUMAN
Sequence: MLNFGASLQQTAEERMEMISERPKESMYSWNKTAEKSDFEAVEALMSMSCSWKSDFKKYVENRPVTPVSDLSEEENLLPGTPDFHTIPAFCLTPPYSPSDFEPSQVSNLMAPAPSTVHFKSLSDTAKPHIAAPFKEEEKSPVSAPKLPKAQATSVIRHTADAQLCNHQTCPMKAASILNYQNNSFRRRTHLNVEAARKNIPCAAVSPNRSKCERNTVADVDEKASAALYDFSVPSSETVICRSQPAPVSPQQKSVLVSPPAVSAGGVPPMPVICQMVPLPANNPVVTTVVPSTPPSQPPAVCPPVVFMGTQVPKGAVMFVVPQPVVQSSKPPVVSPNGTRLSPIAPAPGFSPSAAKVTPQIDSSRIRSHICSHPGCGKTYFKSSHLKAHTRTHTGEKPFSCSWKGCERRFARSDELSRHRRTHTGEKKFACPMCDRRFMRSDHLTKHARRHLSAKKLPNWQMEVSKLNDIALPPTPAPTQ
What is the function of this protein?
Transcriptional repressor which binds to the consensus sequence 5'-GGTGTG-3'.  Plays a role in the regulation of the circadian clock; binds to the GC box sequence in the promoter of the core clock component ARTNL/BMAL1 and represses its transcriptional activity.  Regulates the circadian expression of genes involved in lipogenesis, gluconeogenesis, and glycolysis in the liver.  Represses the expression of PCK2, a rate-limiting step enzyme of gluconeogenesis (By similarity).  May play a role in the cell cycle regulation.
What are the official names of this protein?
Krueppel-like factor 10, EGR-alpha, Transforming growth factor-beta-inducible early growth response protein 1, TGFB-inducible early growth response protein 1, TIEG-1.
What is the protein family that this protein belongs to?
Belongs to the Sp1 C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NUCS_BIFA0
Sequence: MRIIVADCCAEYTGRLSASLPLAKRVLLIKADNSLLIFSEIGSYKPLNWMLSPCTIKDITPQDADDDPATPTPEKIIRVQSTKTNDVLEVTLQHIYSDETHDLGTDPGLRKDGVEDHLQRYLAEQIERIGEGAKLVRREYPTAIGPVDIMAIDADGTHVAIEIKRHGGIDGVEQLTRYCELLNRDPLLAPVRGIFAAQTITPQAQVLAKDRGFDCLLLDYDDMKGTDDGALRLF
What is the function of this protein?
Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
What are the official names of this protein?
Endonuclease NucS.
What is the protein family that this protein belongs to?
Belongs to the NucS endonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYCE1_HUMAN
Sequence: MAGRSLTSKAEPTAGAVDRAEKAGGQDTSSQKIEDLMEMVQKLQKVGSLEPRVEVLINRINEVQQAKKKANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSSKEQLLKEEKLVKATLEDVKHQLCSLCGAEGPSTLDEGLFLRSQEAAATVQLFQEEHRKAEELLAAAAQRHQQLQQKCQQQQQKRQRLKEELEKHGMQVPAQAQSTQEEEAGPGDVASPKPLKGERPGAAHQAGPDVLIGQEDTLHPDLSPRGFQEIKELF
What is the function of this protein?
Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase.  Requires SYCP1 in order to be incorporated into the central element.  May have a role in the synaptonemal complex assembly, stabilization and recombination.
What are the official names of this protein?
Synaptonemal complex central element protein 1, Cancer/testis antigen 76, CT76.
What is the protein family that this protein belongs to?
Belongs to the SYCE family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Associates with chromatin. In prophase I stage of meiosis, localizes in the transverse central elements of the central region between lateral elements of the synaptonemal complexes. Found only where the chromosome cores are synapsed. Colocalizes with SYCE2 in the central elements.
Protein: MURA_BRUMB
Sequence: MDRIKIVGGNKLNGVIPISGAKNAALPLMIASLLTDDTLTLENVPHLADVEQLIRILSNHGVDYSVNGRREHQNGPYSRTIHFTARNIVDTTAPYELVSRMRASFWVIGPLLARMGEANVSLPGGCAIGTRPVDLLLDALLALGAEIDIENGYAKAKARNGLVGARYKFPKVSVGATHVMLMAATLAKGETIIENAAREPEVANLADCLNAMGAKISGAGSSTIHVQGVTNLSGARVRIIPDRIEAGTYAMAVAMTGGDVLLEGAQESQLSCVLETLRQAGAEINETNSGLRVVRNGHGIQPVDITTDPFPGFPTDLQAQFMGLMTRAKGTSHITETIFENRFMHVQELARLGAKISLSGQTATVEGVERLKGAQVMATDLRASVSLVIAGLAAEGETIVNRVYHLDRGFERLEEKLSRCGADVKRISG
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCUP_FLAJ1
Sequence: MLKNDLFLKALKGETVQRPPVWMMRQAGRYLPEFIELRDKYDFFTRCQTPELAAEITVQPIRRIAPDAAILFSDILVVPQAMGIEVLMKENIGPFIPNPIRSMADVQRVYVPDIQESLGYVMDAIKLTKEMLNDEVPLIGFAGSPWTIFCYAVEGRGSKSFDMAKGFCFSNPVAAHTLLQKITDTTILYLKEKVKAGVDAVQIFDSWGGMLSPVDYQEFSWKYINQIVEALADLTPVIVFGKGCWFALGEMGKSRASALGVDWTCSARNARYLSGGNITLQGNFDPSRLLSPIPTIKKMVHEMIDEFGKDKYVVNLGHGILPNIPVDHAKAFIDAVKEYGQ
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PORTL_BPT4
Sequence: MKFNVLSLFAPWAKMDERNFKDQEKEDLVSITAPKLDDGAREFEVSSNEAASPYNAAFQTIFGSYEPGMKTTRELIDTYRNLMNNYEVDNAVSEIVSDAIVYEDDTEVVALNLDKSKFSPKIKNMMLDEFSDVLNHLSFQRKGSDHFRRWYVDSRIFFHKIIDPKRPKEGIKELRRLDPRQVQYVREIITETEAGTKIVKGYKEYFIYDTAHESYACDGRMYEAGTKIKIPKAAVVYAHSGLVDCCGKNIIGYLHRAVKPANQLKLLEDAVVIYRITRAPDRRVWYVDTGNMPARKAAEHMQHVMNTMKNRVVYDASTGKIKNQQHNMSMTEDYWLQRRDGKAVTEVDTLPGADNTGNMEDIRWFRQALYMALRVPLSRIPQDQQGGVMFDSGTSITRDELTFAKFIRELQHKFEEVFLDPLKTNLLLKGIITEDEWNDEINNIKIEFHRDSYFAELKEAEILERRINMLTMAEPFIGKYISHRTAMKDILQMTDEEIEQEAKQIEEESKEARFQDPDQEQEDF
What is the function of this protein?
Forms the portal vertex of the capsid (PubMed:2685327, PubMed:24126213).  This portal plays critical roles in head assembly, genome packaging, neck/tail attachment, and genome ejection.  The portal protein multimerizes as a single ring-shaped homododecamer arranged around a central channel.  Binds to the terminase subunits to form the packaging machine.  Attaches to the host inner membrane most likely through interaction with host yidC and forms together with chaperone gp40 an initiator complex to form the prohead.
What are the official names of this protein?
Portal protein, Gene product 20, gp20.
What is the protein family that this protein belongs to?
Belongs to the Tevenvirinae portal protein family.
What are the subcellular locations of this protein?
Virion. Host cell inner membrane. Note=Located at a unique 5-fold vertex of the icosahedral capsid. Localization at the inner host membrane is likely due to interactions with host membrane proteins such as yidC.
Protein: MURG_BRUME
Sequence: MDNLANQGVIVLAAGGTGGHLFPAEALAHELRARGWDVHLATDARAQRFVGAFAQDHVHVIRSATIAGRNPVALLKTFWSLWQGNLDSRKLFRRLKPKLVVGFGGYPTLPPLYAASNMGIPTLIHEQNAVMGRANKGLAGRVKAIAGGFLPENSGAYAAKTVITGNPVRSPVLVAAATPYTPAGKDDRFRLLVFGGSQGAQFFSQAIPAAVALLPEHERARLLITQQARKEDEASARQAYEKLGVPADVAPFFNDMPARMADAHFVIARSGASTVSEITVIGRPAMLVPFPHALDHDQAANAAALAAAGGAEVVRQADLSPQRLAEMLQSAMNELERLEQQAKAAKSVGKPDAARLLADLAEAIASGKTVQEFKEGNRP
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NUSB_CORJK
Sequence: MTEERTADNKAAKAASFKRHGSRYKARRRAVDILFEAEFRDIDPVEIVEERISLAKDSANQVKPVPEYTQQIVPGVATNLDALDEAIALHLSSDWQLDRLPAVDRAVLRVAAWELKFNDDVPPQVAVVEGVELASEYSHDKAPSYIHAVLDGINKDLQLQADLKIADASAAKRAEQAEQPGQAESDELDGLLDGVVQESDEA
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: RK36_POPTR
Sequence: MKIRASARKICEKCRLIRRRGRILIICSNPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LALBA_ORNAN
Sequence: RIFQICELSRVLKENGLGGFHGVSLEEWLCVIFHESGYDSQALNYYNGSSSHGLFQINQPYWCDDXDSESTEPSVNACQIPCSKLLDDDILDDIECAKKIVKEPKGITAWEAWQPFCNSDLDQWKC
What is the function of this protein?
Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme.  This enables LS to synthesize lactose, the major carbohydrate component of milk.  In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins.
What are the official names of this protein?
Alpha-lactalbumin, Lactose synthase B protein.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y3485_CHRVO
Sequence: MEWLTGLPRVAGLFVLTALAEIVGCYLPWLVLREGRSLWLLAPTTLALALFAWLLTLHPAAAGRTYAAYGGVYVTVAIAWLWLVDGVRPDRWDALGCALALAGMAVIMLAPRS
What are the official names of this protein?
UPF0060 membrane protein CV_3485.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS2_LEIAM
Sequence: MADTQPAQEAPAADAPRAERNFGRGRGGRGGRGRGRGGPGEEKEWVPCTKLGRLVKAQKVTSLEEIFLFSMPIKEHQIVDTLIAEGKLHDEMMKIYPVQKATSAGQRTRFKAFNVVGDCDGHIGIGARVGKEVSLAIRASMIAAKLNIVPVRRGYWGNKIGEPHTIPMKVTGKCGSVAVRLVPAPRGTGIVAAPVPKKILEFAGVEDVYTSSRGKTRTHGNLIMATFYALRKTYGFLTPDLWADTEPSRDPTDEHGELLAEMTTA
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.  Plays a role in the assembly and function of the 40S ribosomal subunit.  Mutations in this protein affects the control of translational fidelity.  Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
What are the official names of this protein?
40S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: PSB5_SPIOL
Sequence: MKLDTSGLESTAPIFRRSDFVFDGLQMTPSFDLPNPTDFDGFQKEAVQMVKPAKGTTTLAFIFKHGVMVAADSRASMGGYISSQSVKKIIEINPYMLGTMAGGAADCQFWHRNLGIKCRLHELANKRRISVTGASKLLANILYNYRGMGLSVGTMIAGWDETGPGLYYVDSEGGRLKGMRFSVGSGSPYAYGVLDNGYKYDMTVEEASELARRAIYHATYRDGASGGVVSVYHVGPDGWKKVTGDDVGDLHFQYYPVVPATVEQEMVEVVGA
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.
What are the official names of this protein?
Proteasome subunit beta type-5, 20S proteasome subunit E, Proteasome epsilon chain.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RHO_CHRVO
Sequence: MHLSDLKHLHVSELVEMAISNEIDGANRLRKQDLIFALLKNQAKKGESIFGEGTLEVLPDGFGFLRSPDTSYLAGPDDIYVSPSQIRRFNLHTGDSIEGEIRTPKDGERYFALVKVDKVNGEAPENSKHKILFENLTPLFPTEQFKLEREIRAEENITGRIIDLISPIGKGQRALLVAPPKSGKTVMLQHIAHAITANHPEAVLIVLLIDERPEEVTEMQRSVRGEVVSSTFDEPATRHVQVAEMVIEKAKRLVEHKKDVVILLDSITRLARAYNTVVPASGKVLTGGVDANALQRPKRFFGAARNVEEGGSLTIVATALIDTGSRMDDVIYEEFKGTGNSEIHLDRRMAEKRIFPALNINRSGTRREELLVPQDQLQRIWVLRKLLYPMDDLEAMEFLQDKIKATKSNQAFFDSMRR
What is the function of this protein?
Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
What are the official names of this protein?
Transcription termination factor Rho, ATP-dependent helicase Rho.
What is the protein family that this protein belongs to?
Belongs to the Rho family.
Protein: ERF1_MESAU
Sequence: MADDPSAADRNVEIWKIKKLIKSLEAARGNGTSMISLIIPPKDQISRVAKMLADEFGTASNIKSRVNRLSVLGAITSVQQRLKLYNKVPPNGLVVYCGTIVTEEGKEKKVNIDFEPFKPINTSLYLCDNKFHTEALTALLSDDSKFGFIVIDGSGALFGTLQGNTREVLHKFTVDLPKKHGRGGQSALRFARLRMEKRHNYVRKVAETAVQLFISGDKVNVAGLVLAGSADFKTELSQSDMFDQRLQSKVLKLVDISYGGENGFNQAIELSTEVLSNVKFIQEKKLIGRYFDEISQDTGKYCFGVEDTLKALEMGAVEILIVYENLDIMRYVLHCQGTEEEKILYLTPEQEKDKSHFTDKETGQEHELIESMPLLEWFANNYKKFGATLEIVTDKSQEGSQFVKGFGGIGGILRYRVDFQGMEYQGGDDEFFDLDDY
What is the function of this protein?
Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.  Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.  Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF) of mRNA from viruses and cellular genes.
What are the official names of this protein?
Eukaryotic peptide chain release factor subunit 1, Eukaryotic release factor 1, Protein Cl1, eRF1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family.
Protein: GSA_CHLL2
Sequence: MPQLTKSAELFELAKKFIPGGVNSPVRAFKSVGGTPIYMAKGEGAYMTDVDGNTYLDYVGSWGPFILGSMQPRVTAAIEYTLRNIGSSFGTPIEMEIEIAELLSRIVPSIEMVRMVNSGTEATMSAVRLARGYTGRDKIIKFEGCYHGHGDSFLIKAGSGVLTLGSPDSPGVTKGTAADTLNATYNDIESVRLLVNENRGDIAAIIIEPVAGNTGVIPAKKEFLVALRELCDQEGIVLIFDEVMCGFRVALGGAQELYGVTPDLTTMGKIIGGGLPVGAFGGKRKIMENVAPLGSVYQAGTLSGNPLALTAGLETLKILMEEDPYPELERKAAFLEAGFRENMQKLGLNYVQNRVGSMACLFFTETPVVDYKSAITADVAKYGKYFHSMLDQGIYLAPSQFEAMFTSYVHSDEDLEKTVKANYNALVAAHQ
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADA_SALEP
Sequence: MSVMFDPQAAIYPFPPKPTPLNDDEKQFYREKIKRLLKERNAVMVAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHAASTLLVAGVRFMGETAKILSPEKNILMPTLAAECSLDLGCPIDEFSAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAVELIEHLDSLGEKIIWAPDRHLGNYVQKQTGADVLCWQGACIVHDEFKTQALTRLKKIYPYAALLVHPESPQSIVEMADAVGSTSQLIKAAKTLPHRQLIVATDRGIFYKMQQAVPEKELLEAPTAGEGATCRSCAHCPWMAMNGLKAIAEGLEQGGAAHEIQVDAALREGALLPLNRMLDFAATLRA
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_POLNS
Sequence: MAKKIIGFIKLQIPAGKANPSPPVGPALGQRGLNIMEFCKAFNAQTQSMEPGLPIPVVITAFADKSFTFIMKTPPTTIMIKKAAKIEKGSPRPHTDKVGSITRAQAEEIAKAKMPDLTAADMDAAVRTIAGSARSMGITVEGF
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: NUOC_BRUA2
Sequence: MSEEALGELSGYIRERLGDAIEEANLAYGELTLCVPVASLIGVLTLLRDDVQCQFVNLTDISGVDYPQREKRFDVVYQLLSPRQNQRIRVKVQADEDTLVPSAVPVFFGAEWYEREAYDMYGILFSGHPDLRRILTDYGFEGHPLRKDFPLTGFVEVRYNDELKRVVYEPVQLRQEFRNFDFLSPWEGTDYVLPGDEKAKTN
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SYP_STRPG
Sequence: MKQSKLLIPTLREMPSDAQVISHALMVRAGYVRQVSAGIYAYLPLANRTIEKFKTIMREEFEKIGAVEMLAPALLTADLWRESGRYETYGEDLYKLKNRDNSDFILGPTHEETFTTLVRDAVKSYKQLPLNLYQIQSKYRDEKRPRNGLLRTREFIMKDGYSFHHNYEDLDVTYEDYRQAYEAIFTRAGLDFKGIIGDGGAMGGKDSQEFMAITPARTDLDRWVVLDKSIASMDDIPKEVLEEIKAELAAWMISGEDTIAYSTESSYAANLEMATNEYKPSSKVAAEDALAEVETPHCKTIDEVAAFLSVDETQTIKTLLFVADNEPVVALLVGNDHINTVKLKNYLAADFLEPASEEEARAFFGAGFGSLGPVNLAQGSRIVADRKVQNLTNAVAGANKDGFHVTGVNPGRDFQAEYVDIREVKEGEMSPDGHGVLQFARGIEVGHIFKLGTRYSDSMGAKILDENGRAVPIVMGCYGIGVSRILSAVIEQHARLFVNKTPKGDYRYAWGINFPKELAPFDVHLITVNVKDQAAQDLTAKLEADLMAKGYDVLTDDRNERVGSKFSDSDLIGLPIRVTVGKKAAEGIVEIKIKATGDSIEVNAENLIETLEILTKEH
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPP2_PYRTR
Sequence: MEVLDATGLAERLRWEDNDYLLHLKAETSFDKYPAKQHARRVQAELGVEDGLIYLPGQPARNNEDSDMPAPFRQRRYFYYMSGCDEPDCHLMYDIRRDVLTLFIPRIKPERVIWNGRGSTPAEALAKYDIDQVHHSQDLAYIIQNWAFKHQNTGIYILHPSSRIPGCDNLMPRIDSHSLQPAMNLCRMIKDDHEIKRIRKANDISSQAHREVLANIQKYKNEAQVEGLFMDVCISRQAKQQAYDPIAASGPNAGTLHYDANNEDLAGRQLMCLDAGCEFELYASDITRTFPLSASWPSKEAENIYNLVQRMQETCIERLEPGVRYLDLHIMAHQVAIDGLLRLGILCNGTREEIYKAGTSRAFFPHGLGHHIGLEVHDVGQAELMSVRRGKPVYQQAPSLYPENFHDPVYDSETCHAPTDPQSSHLEEGMVVTVEPGIYFSVYALQHFYLPSPIHSKFINLEVLERYLPVGGVRIEDDILITANGHENLTTAPKGEAMLDMIRQGKPGTTDVLIPSPTYSRRMRSENNTPRLCAPGISKNTLRPLLTPLARAATLPTEFRQQDDFDFEPTVGPSLFSGFSRAMTTEEKIQQWKQKRDSVPVALNRPTKAKSLSPVCGENTPNVQHVYMSTASDLASFSQLSAGSGSTPLWKPHNKQDKKN
What is the function of this protein?
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.
What are the official names of this protein?
Probable Xaa-Pro aminopeptidase PTRG_10574, Aminoacylproline aminopeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: POL_COYMV
Sequence: MATRRLPAVTQTDGSRTATESGVPEYEDQIRSYRNDQRRRHIWAGRGRRLLSIMPGVSSSERTLEMQMNPEVQLQRSMNHRAEAVPAEVLYRTFHGSVNHRVYSHRSEERMMVVNGSQVDRSFIQESSFEVLSRTGIEFIHIGVMLVRIQILHRKFAGTMALIVFRDTRWSDDRAVLAAMEIDLSEGNQIVYVLPDIMMTIKSFYRHIQICVMTKGYDGWQGEDNLLITRGLTGRLSNTSNVGFAYDVKAMVEHLQSNGVKAIKGEKWDAKRFHNGQWNIEPSKVVVPMQPTEMKAVSNYDGTTSLRFSNYAAASTSKPPQYNEKDEEINEDEQEINHSLNLILNDEESTDEDEEYYQYQRYAWSQVGDSTFYYDTDGVWEEIDRCNDLPEYVPSETSTPTIDESEAIIDEFLEHAYEQRCDSDESLQSGDPRKYEYPTPQSSPEHLDNESRSRSSSASSTSMQDDVEEIVRLMKEMRMKKQKKKKAQQALSSQAQEEPIIEENIEENKQAQEEPTQEEIPTHKENQPEEIQNEEIHVFEEEPAFKHLAAQLSELVNMAESSGQSGVGFQPPVNAQPDVNMEGPAGYAPATSQATWSNGVNIPVKSANFRWKGPVGNFQLPSAQGKDGAMLVFGMNYSPEVFDRWASITRNYISSFNFNDGGDKIAWMEDLLGETERKIFVSWRMRFKDEYQNLAKIANQDGGTQAILSQIRRIFLGEDPVLGQNTVQNIAFRKLKQLVCPNYQSIRRYLMDYLTLAAETGLMWSETEGPAISEELFTKMPAAIGERVAQAYKIMDPTSAVNLPSRVYFTINYLTEQCKEASYMRSLKALDFCRDFPIEGYYGRSGEKKKYTARKATKYTGKAHDNHIRVTKAKYQRKCKCYICGQEGHYANQCRNKHKDQQRVAILQSLDLKENEEVVSADDKEEEDDEIFSVLGEEDYQEETIMVLEEDDIQQIIKEFSKFGDLSRRNVGPNFPGPAEVQMGVLKPKSSWRRPIQATLEEINCHHNWTAISTGQLACRSCKQFLAGVQCHHCHAVYCFMCAEAYHDVQAEKILSKDYSFSARGKKGKAVIIEEDEIEGEFLISQLQQENQRLQKQVERLQEELMKLHREKDEALKHSEKASRVFSTIQESDEAELNLIKEELRQFKEETRMAIAQLKEAIIVQEEDTIEERCAMILEEKHTENIYSATAKAEYNGLYNVKVGIKPDNMEPYYINAIVDTGATACLIQISAIPENYYEDAKVTVNFRSVLGIGTSTQMIKAGRILIGEQYFRMPVTYVMNMGLSPGIQMIIGCSFIRSLEGGLRIEKDIITFYKLVTSIETSRTTQVANSIEELELSEDEYLNIAASVETPSFLDQEFARKNKDLLKEMKEMKYIGENPMEFWKNNKIKCKLNIINPDIKIMGRPIKHVTPGDEEAMTRQINLLLQMKVIRPSESKHRSTAFIVRSGTEIDPITGKEKKGKERMVFNYKLLNENTESDQYSLPGINTIISKVGRSKIYSKFDLKSGFWQVAMEEESVPWTAFLAGNKLYEWLVMPFGLKNAPAIFQRKMDNVFKGTEKFIAVYIDDILVFSETAEQHSQHLYTMLQLCKENGLILSPTKMKIGTPEIDFLGASLGCTKIKLQPHIISKICDFSDEKLATPEGMRSWLGILSYARNYIQDIGKLVQPLRQKMAPTGDKRMNPETWKMVRQIKEKVKNLPDLQLPPKDSFIIIETDGCMTGWGAVCKWKMSKHDPRSTERICAYASGSFNPIKSTIDAEIQAAIHGLDKFKIYYLDKKELIIRSDCEAIIKFYNKTNENKPSRVRWLTFSDFLTGLGITVTFEHIDGKHNGLADALSRMINFIVEKNDESPYRFTSSVEDALKVCNDDHGRNLISAVINDIITVLRR
What is the function of this protein?
Capsid protein self assembles to form a bacilliform capsid about 90-900 nm in length.  The capsid encapsulates the genomic dsDNA.  Following virus entry into host cell, provides nuclear import of the viral genome.  Virus particles do not enter the nucleus, but are targeted to the nuclear membrane through the interaction with host importins (By similarity).
What are the official names of this protein?
Polyprotein P3.