PharMolix/UniProtQA huggingface dataset:
Protein: HNRPQ_MOUSE
Sequence: MATEHVNGNGTEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDERAIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKSFSQFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGGYEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAGYSQRGGPGSARGVRGARGGAQQQRGRGVRGARGGRGGNVGGKRKADGYNQPDTKRRQTNNQNWGSQPIAQQPLQGGDHSGNYGYKSENQEFYQDTFGQQWK
What is the function of this protein?
Heterogeneous nuclear ribonucleoprotein (hnRNP) implicated in mRNA processing mechanisms.  Component of the CRD-mediated complex that promotes MYC mRNA stability.  Isoform 1 and isoform 2 are associated in vitro with pre-mRNA, splicing intermediates and mature mRNA protein complexes.  Isoform 1 binds to apoB mRNA AU-rich sequences (By similarity).  Isoform 1 is part of the APOB mRNA editosome complex and may modulate the postranscriptional C to U RNA-editing of the APOB mRNA through either by binding to A1CF (APOBEC1 complementation factor), to APOBEC1 or to RNA itself (By similarity).  May be involved in translationally coupled mRNA turnover.  Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain (By similarity).  Interacts in vitro preferentially with poly(A) and poly(U) RNA sequences.  Isoform 2 may be involved in cytoplasmic vesicle-based mRNA transport through interaction with synaptotagmins.
What are the official names of this protein?
Heterogeneous nuclear ribonucleoprotein Q, hnRNP Q, Glycine- and tyrosine-rich RNA-binding protein, GRY-RBP, NS1-associated protein 1, Synaptotagmin-binding, cytoplasmic RNA-interacting protein, pp68.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleoplasm. Microsome. Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs (By similarity). Isoforms 1 and 2 are expressed predominantly in the nucleoplasm. According to PubMed:10734137, isoform 2 is predominantly found in cytoplasm. The tyrosine phosphorylated form bound to RNA is found in microsomes.
Protein: RRAA_ALTMD
Sequence: MEYNTSELCDLFADSVDVVDPIFASFGGRYSFGGEITTVKCFEDRGLIDRVLAQPGAGKVLLIDGGGSSRRALFDASSAQVAIDNDWEGVVIYGSVREVDSLAELDIGVLAVAAIPVNAECESVGEVDLPVNFGGVTFLPEDHLYADSTGVILSPEPLDLD
What is the function of this protein?
Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity.  Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.  Modulates RNA-binding and helicase activities of the degradosome.
What are the official names of this protein?
Regulator of ribonuclease activity A.
What is the protein family that this protein belongs to?
Belongs to the RraA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FDHD_STRCO
Sequence: MGRVTERRKVIRIRDGAVSTRPDTLVAEEPLEIRLNGKPLAITMRTPGDDFALAAGFLVSEGVLAEQRDLQNIVYCAGATVDGSNTYNVVDVKTAPGVRIPDITLERNVYTTSSCGLCGKASLDAVRTTARWPIADTPPVRVTPELLADLPDRLRASQRVFDRTGGLHAAALFTEDGELVDVREDVGRHNAVDKLVGRALQNADLPLSRSVLLVSGRASFELAQKAVMAGIPVLAAVSAPSSLAVDLAAETGLTLVGFLRGSSMNVYAGADRVALRAAVGQG
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity.  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
What are the official names of this protein?
Sulfur carrier protein FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPOM_MAIZE
Sequence: MQPARRHTKKKNMNYMRYESLTREQFERFLKDVHKCYRGEPRYVIPYEGHLIAVQDFEEPYPKAGAVTMLASAFMELLINRVYPSIQGSAKFTLQYRLNIDGNPINITLSKAIKLTYADGTRIANEFILKEIINVLNKYAENYQSCDVEAISVRAYSEGSIDLNQASIPTKDESLNYLKGALIKYSDINNLEIPKMGRRSKRRYQSYIPVDKTEMKNKTLFFVADLETLLLKRRDTDVDKTHVPYAGGYMMVDMEKWVNADHITTFYAHDYSKVCQDFHDMSEKMLTEMINRIVKDVQRRGSSMVVYFHNLSQFDGIMILSFLTKSYKNCHIEPIMRNDCIYSIKLYKVSKNGDKRLVLTFMDSYLLLKVKLADLADSFCPELGGKGSFDHQNVTVDKLPSIREDSLTYLKQDILITAAVMQRAKAIIWEEYGIDILKVLTISALALKIFRRVYYKDDDDNWIYIPDDNEAQFIREGYYGGHTDVYKPYGENLYYYDVNSLYPSSMLDDMPIGKTRWVSDLGSKKSKIVLNDMFGFIRAFIICPKHIKKPLLPYKKDDGTIIFPTGRFLGVYFSEELKYAVSLGYKVYPICGYIFDRKESPFKRFVYDIYSKRLDAKAKGEKALDFIYKITMNSLYGRFGISPESTTTQIVSTEESRKLALYNDGFVQSYELSSDKCLVTCKNVRSLDLLKLSSDRPTYAAVQISAAVTGYARIRMHPFISRDDCYYTDTDSVVVERELPEEEVSPTALGKFKHEHFVEYGIFLAPKSYMLKASSVDQPIIKFKGAGKDEADEEWFINQLADPRAKKVISYVRKFSRNFRELLVQEKMCKYTMGLESKKREYVFDKNGVWVDTKPCHIGDFDVKSINPTSYWIIMNLLEENEDLRNEFSNSEIMIANWEIKADAAKKRKASKLRGKPLRGGDTPSHIEE
What are the official names of this protein?
DNA polymerase, S-1 DNA ORF 3.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RS12_HYDS0
Sequence: MPTVNQLIKEGREKIKKKSKAPALQGNPQKRGVCVRVYTVTPKKPNSALRKVARVRLSNGIEVTCYIPGEGHNLQEHSIVLVRGGRVKDLPGVRYKIIRGALDTAGVANRRQSRSKYGAKRPKAGAAQATKGGKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: IF2_DESRM
Sequence: MTKKRVHELAKELNIENKELINKLMQIGISVKSHMSALENDAVEKVYHQYGKKQEKSSDSANKQIQREHGRGQGMEDKKEKDQLFRPDNAKGPGLVDRVPNRPPDRRYEDKAKVAQKPAQELRGSKTTTNSENEQTAPRQGSAQQSGQGRPQANRPQGSQGRPYGGRPQGGQSRPYGDRPQGGQGRPYGDRPQGGQGRPYGDRPQGGQGRPYGDRPQGGQGRPYGDRPQGGQGRPYGDRPQGGQGRPYGDRPQGGQSRPYGDRPQGGQGRPYGDRPQGGQSRPYGDRPQGGQGRPYGDRPQGGQGRHYGDRPQGGQGRPQGAGRPGANRGAGPSIPKPPEQVAQPKPTKAPDKTKGDRRKNYEKDGKWADGQIEKNKLFKGRNNKNKKRQHQQSAPPPILDKKPVQIAEVITVQELAEKLKKTAAEVIKKLMGLGVLATINQEVDFETATLIAGEYGIETELKVAVDKEALVMAEPEEDEDKLVLRPPVVTIMGHVDHGKTSLLDAIRETNVTAGEAGGITQHIGAYQVERNGKKITFVDTPGHAAFTSMRARGAQITDIAILVVAADDGVMPQTIEAINHAKAANVPIIVAINKMDKPDANPDKVKQELTQHELVVEDWGGDVIAVPVSAKNRTGLDNLLEMILLVAEVHELKANPDRMARGTVVEAELDKGRGPVATVLVQNGTLNVGDTIVVGQVSGRVRAMIDDKGRRVKKAPPSTPVEILGLSDVPEAGDILVAVEDEKLARDVAEKRKIRKREEGLKSSTKISLDDLFKHIQEGQIKELPIIVKADVQGSIEALAQALEKLTTEEVKVNLIHTGVGAVNETDIMLATASNAIVIGFNVRPDNNARKLADAEKVDINLYRVIYEVIDDVKKAMSGLLDPEFKEVVLGHVEVRKTFKASKIGTIAGGYVTEGKIVRDASVRVIRDGIVVFEGKLDSLKRFKDDAKEVAQGYECGLTIDRFNDVQEGDIIEAFTMEAIKREI
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDD_RHIEC
Sequence: MCEFCVRQADDEDDGGAAASGRPNARTARYSRNYAGPFRKTPDRLLGMGLIRLYQLTLSGFVGNSCRHIPTCSEYGYEAIARHGLWAGGWMTLFRVARCGPGGTSGLDPVPEILSDGFRWWTPRRYLSLGRKRG
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CYB_EPTBU
Sequence: MTKIFRKSNPLNKMINSSLIDLPSPSNISYLWNFGSLTGLCLALQIISGLLLTMHFSPSINLAFDSTVHIVRDVYGGWFIRNVHISGASLFFTCMFIHIGRGIYYGSFKNLKTWYSGVILFILSMLTAFLGYVLPWGQMSFWAATVITNLLSAVPMMGGTLVETVWGGYSVGDPTLKRFLVLHFLMPFSMIAVSLIHLVFLHETGSNNPMGINPNMDKIPFHPYLSFKDILGFSFLLTFLITFSLLLPYLTTDPDNFSPANSMVTPPHIKPEWYFLFAYSILRAIPNKLAGIIALVMSLSVLLLMPILIRSNKRSMTFMPLMQVTFWLMVCNFIFLSWLGAMPLEPPFILMSQISSFIYFFIFFVMFPLISRNEDKILEFHAMYS
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: LEU1_PROM0
Sequence: MSKNPGRILIFDTTLRDGEQSPGASLNLEEKLAIAHQLARLGVDVIEAGFPFASPGDFKAVNKIASAVGKEHGPTICGLARASKGDIKACYEAVSPAPKKRIHTFIATSDIHLKHKLKKSRKDVLQIVPEMVNYAKSLVDDIEFSCEDASRSDPDFLYEVIQLAISAGATTINIPDTVGFTTPSEFGNLIADINKNVPNIDEAVISVHGHNDLGLAVANFLEAVKNGARQLECTINGIGERAGNASLEELVMALHVRKSFFNSFFKRNPDSPTPLTAIRTEEITKTSRLVSNLTGMTVQPNKAIVGANAFAHESGIHQDGVLKNRLTYEIIDAKTVGLSDNKISLGKLSGRSAVRARLEEMGYDLSREDLNDAFARFKDLADRKREITDRDLEAIVSEQVQLPEAKFQLSLVQVSCGNASKPTATISLLNTEDNTEDTAVSIGTGPVDAVCEALNKLAKVPNELIEFSVKSVTEGIDALGEVTIRIRRDNKIYSGHSADTDVVVAAANAYINALNRLVFSEKKNSIHPQFDNLENSNNTYISNPAN
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: MDH_WOLWR
Sequence: MTVQRKKISLIGAGNIGGTLTHMIALRELGDVVLLDISDGIPQGKALDIAESSPIDGFNVNITGTNRYEDIKNSDAIIITAGIARKPGMSRDDLLQTNAKVMKEVGENIKKYSPNAFVIVVTNPLDAMVSVVHKFSNLPTNMIVGMAGVLDSSRFRYFLASELNISVEDISAFVLGGHGDTMVPLINCASVAGVPLTQIIDMGLITQKKVDEIVERTRNGGKEIVDLLKSGSAYYAPASSAICMLESYLKDKRRILPCAAYLNGEYGVEELFIGVPVIIGKNGIEKILEVKMNDSEQEMFNKSVNSVRELVKSLGS
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: METN1_BACCR
Sequence: MIELKNVSKVFTTKKVNVEALKSTSLQVKKGEVFGIIGYSGAGKSTLIRCVNLLEKPTTGNIIVNNQDLTTLSAKELAKARQKIGMIFQGFNLLKTVTVYENIALPLRLAGIPKTEIEKRVEKYLRIVDLFNRKDAYPSELSGGQKQRVAIARALSHEPEVLLSDEATSALDPETTDSILDLLLKINEEIGITILLITHEMNVIQRICDRVAVMEHGAVIESGTVKEIFTNPQHVTTKKFVNSAFAAKIPAEVQKELQRTGEIVTLSFIGNSSGEPALAIATKRFQVYPNILSGNITQLKHEAYGKLVIHMQGEQNEINHALSFLQEQGIIVEGGRTDYGKQVLFG
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: LEC10_MEDTR
Sequence: MALSNLKSNRTLSSSLITIFIISLFLQYHNIKSQSSWQSRQVPRSETVAFSITEFEKENPDIFLRGDTSISDGILRLTKTDQSGKPLPNTVGRATYLTPIHIWDKTSGELADFSTSFSFIVNTNDSDLHGDGFAFYLGPLHFDVPKNSSGGYLGLFDPENAFPPSKTPILAIEFDGFTNEWDPPSSFQSPHIGIDVGSIVSLEYAQWPINFVPRNALGEANINYNSESKRLSVFVAYPGTQWNSTRVSVVVDLRSVLPEWVRIGFSATTGELVETHDIINWSFESAL
What is the function of this protein?
May be involved in arbuscular mycorrhizal (AM) symbiosis with AM fungi.
What are the official names of this protein?
Lectin 10, MtLec10, Agglutinin LEC10.
What is the protein family that this protein belongs to?
Belongs to the leguminous lectin family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: Y076_MYCPN
Sequence: MLWAIVLLGYLLFVVEWFVIDRIAGKPAGILDSNTKVLPNYDGWVNSFFANSAGSIAGSATNWSITLLRAVGSVLCGIVVLKFGYRYAVMIMMGLMCLCFPFLIIGDPLGGNNQLTLLRPLSKEVMGKLSSLSSQLHEGQLLGPVMAEGKTMLADGQTIDLVQGLDKNLIGTSSSIAGYALFIIFRSTIAIGGTTLVTYSQPLIASLSTQRRKSVLSNANLWGFNSGIVVAFVPFLFQSVQQAGTKYWVFILTALILIGFGILCVFAWFEKQMDPFMPQKQTKEQMQLGNQPSAGDILKRKATWKMIGMYGICLVVLVNPLTGGWWNILQAVSPASSFNVKDGVKTLKPLEGAGGYFAGLPTLAILWVLGYGMGYMVFSPFNKTVYDRKRWLSFMFFMNALMVIVIVLFAATLGVGTAVGFAFVAIATFIGGSFAWSMQSTILILPHEFKEYKRSEVSVLFGYIWGFGYVIYTAFDITNSMFLEAPKLANPGMKGVSILPGAIAGVALFAGLLLAAIAIVVTLPSSYLKNGDELVSEMTKKWKLNQWQFLVASKEKNRYADLLK
What are the official names of this protein?
Major facilitator superfamily transporter MPN_076.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EST5A_DROMI
Sequence: MHLVRWLICLIQLWIQLGAAGSVTLLDPLLIEIPNGKLRGRDNGHYYSYEAIPYAEPPTGELRFEVPKPYKQQWTNTFDATQPPVLCMQWNQFINGTNKLLGVEDCLTVSVYRPKNSSRNNFPVVANLHGGAFMFGGPSQYGHENIMREGSVILVTIGYRLGPLGFVSTGDADLSGNFGLKDQRLALLWIKQNIASFGGEPENILVVGHSAGGASVHLQMLREDFSKVAKAAISFSGNALDPWVIQQGLRGRTFELGRIVGCGQASDSVTLKKCLKSKPASEIVSAVQSFLVFSYVPFTPFGPAIESPDAPEAFITQHPIDIIKSGKFAQVPWAVTYTTEDGGYNAALLLEKQASSGRELILDLNDRWFDWAPYLLFYRDSMTTIKDMDDYSRKLRQEYLGDRRFSVESYWDVQRMFTDLLFKNSVTVSVDLHRKYGKSPVYAFVYDNPAEVGVGQILSGRNDVYFGTVHGDDVFLIFNVSFVPANRRPDEQIISRNFIKMLEYFALSTNDTMAYGDCVFQNNVGSKHMQLLSITRDGCENKQLNCFIQRCLIFF
What are the official names of this protein?
Esterase-5A, Est-5A, Carboxylic-ester hydrolase 5A, Carboxylesterase-5A.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: NEU1_BOVIN
Sequence: MAGSSLACCLLGLLALTSACYIQNCPLGGKRAVLDLDVRTCLPCGPGGKGRCFGPSICCGDELGCFVGTAEALRCQEENYLPSPCQSGQKPCGSGGRCAAAGICCSPDGCHEDPACDPEAAFSQH
What is the function of this protein?
Oxytocin causes contraction of the smooth muscle of the uterus and of the mammary gland.  Acts by binding to oxytocin receptor (OXTR) (By similarity).
What are the official names of this protein?
Oxytocin-neurophysin 1, OT-NPI.
What is the protein family that this protein belongs to?
Belongs to the vasopressin/oxytocin family.
What are the subcellular locations of this protein?
Secreted.
Protein: LIS1_YEAS2
Sequence: MTNWQQQLPLTDTQKNELDKSVLRYLNWNYKQTVRHEHAQDYESVRHAIVTLSGFLLQESVDRQEFISNNDTSNESMVDIDELLLPKKWNSIVRLQKKIIELEQNTETLVSQIKDLNTQVSELAQFKPTTSNGTSAHNVLKWIPRNLPSCLINVESSVTSVKLHPNLPIVFVATDHGKLYAFDLFNYTIPLASLQSHTKAITSMDVLFTNFTNSSKKNYLVVVTASKDLQIHVFKWVSEECKFQQIRSLLGHEHIVSAVKIWQKNNDVHIASCSRDQTVKIWDFHNGWSLKTFQPHSQWVRSIDVLGDYIISGSHDTTLRLTHWPSGNGLSVGTGHEFPIEKVKFIHFIEDSPEIRFRTPSTDRYKNWGMQYCVSASRDRTIKIWEIPLPTLMAHRAPIPNPTDSNFRCVLTLKGHLSWVRDISIRGQYLFSCADDKSVRCWDLNTGQCLHVWEKLHTGFVNSLDLDVDFDSNVTPRQMMVTGGLDCKSNVFMR
What is the function of this protein?
Positively regulates the activity of the minus-end directed microtubule motor protein dynein.  Plays a central role in positioning the mitotic spindle at the bud neck during cell division.  Targets cytoplasmic dynein to microtubule plus ends, thereby promoting dynein-mediated microtubule sliding along the bud cortex and consequently the movement of the mitotic spindle to the bud neck.
What are the official names of this protein?
Nuclear distribution protein PAC1, Lissencephaly-1 homolog, LIS-1, nudF homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LIS1/nudF family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes to the plus ends of microtubules and the mitotic spindle poles.
Protein: EBLN2_HUMAN
Sequence: MGYFLKLYAYVNSHSLFVWVCDRSYKRSFRPMILNKIKELSRNQFSTMSHLRKDSQPSSPGDDAMDRSGLPDLQGRFELSGKNRQYPLDALEPQPSIGDIKDIKKAAKSMLDPAHKSHFHPVTPSLVFLCFIFDGLHQALLSVGVSKRSNTVVGNENEERGTPYASRFKDMPNFIALEKSSVLRHCCDLLIGIAAGSSDKICTSSLQVQRRFKAMMASIGRLSHGESADLLISCNAESAIGWISSRPWVGELMFTLLFGDFESPLHKLRKSS
What is the function of this protein?
May act as an RNA-binding protein.  The C-terminal region is highly homologous to the bornavirus nucleocapsid N protein that binds viral RNA and oligomerizes.  The viral protein also possesses a nuclear import and a nuclear export signal.  These 2 signals seem absent in EBLN-2 supporting an unrelated function in Human.
What are the official names of this protein?
Endogenous Bornavirus-like nucleoprotein 2, Endogenous Borna-like N element-2, EBLN-2.
Protein: TF2B_MIMIV
Sequence: MSHHSETILTAILNTKYLENGSKHKIIELPKTNIKKLIKDFLSVNSNKKIQSDCVLINYFPNALLLDNPNKNSSVKKEQTNQVKIIEKPITNNINKPEDIWDIIDNMDKENNSESLENIQSENSENNDNFTDNNTKKSPTKSRICSGCGSKGTLLEDQSSSVLVCSECGMINDDLLDHGPEWRQYYNDDGRGEGVNRCGCPSNFFFPKSSQGTILAGTGSGRLKRKQKWNSTVYKERSLNDVFEKISTICSKSNIPRIIADTAKILYKKLSDCKHKSGNNVGKQIIIRGHNRISIIAACIYKACEMNKNPRTVKEIARFFGIDEKKVTKGNKQFEKIMKNTDDNMIILDPVNSNSTEDYIRRHCPRLKVNKDHTDIAVKISNNCCRMKLASDHNPQSIAAGAILVMVVFCELNIDKRKISRLFGISDVTIDKIYKKIAPYAPALVDDGATDHLINKLKING
What are the official names of this protein?
Putative transcription initiation factor IIB-like protein.
What is the protein family that this protein belongs to?
Belongs to the TFIIB family.
Protein: GLB2_PHRSO
Sequence: VSQADIAAVQTSWRRCYCSWDNEDGLKFYQTLFDSNSKIRHAFESAGATNDTEMEKQANLFGLMMTQFIDNLDDTTALNYKISGLMATHKTRNVVDPALFAIALNELVKFIGNQQPAWKNVTAVILSQMKIALSSN
What are the official names of this protein?
Globin-2, Globin II, Hb II.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: YD228_YEAST
Sequence: MNAVLTRRHGLGDNSLQTNFSLSQFISRWVFDLQSSQSIGQSSFNLGLGTSLQFRRQDWVSDSLFDGGNVGFQSLSSFVLLGKSFIGSLELFSLVNHLFNFFRRQSTNSVRDSDVRRLTGRLFDGSNLQDTVSINFEDSFQDWFTSWHHWDVLQVEFTQQSVFFTVNTFTLVDWELNGGLVVSTCSKGSSLDGWNSSVSWNNDTEHVTLHTNT
What are the official names of this protein?
Putative uncharacterized protein YDL228C.
Protein: DUT_GEOMG
Sequence: MERCVVKVRRVRGGDQNLPCYMTVHAAGMDLCADLVDDLVLNPGERKLVPTGLAIALPDGFEAQIRPRSGLALKHGIALVNSPGTIDPDYRGEIGVILINHGSEPFVVRRGERIAQMVFAPFARAELVEVDELDETARGEGGFGHTGR
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: CLPP_NUPAD
Sequence: MPIGVPKVPFRSPGEEDAVWVDIYNRLHRERLLFLGQGVDSEISNQLVGLMVYLSMEDNTRDLYLFINSPGGWVIPGIAIYDAMQIVPPDVHTICMGLAASMGSFILVGGEFTKRLAFPHARVMIHQPASSFYEAQAGEFILEAEELLKLREILTRVYVQRTGKPLWVVSEDMERDVFMSATEAQAHGIVDLVAVENSADFV
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: RL18_TRYB2
Sequence: MGVDLTGVQKKKRVVRHHTYSTNPYIKLLIKLYKFLGKRTNSPFNKLIHKRLLKSRNNRAPISLSRIAVCMRRRTVWLKKGKKSPIAVIVGDVLDDVRMTRIPALRICALRFSKSARERITGAGGECLTFDQLAMMAPTGKNTMLLRGRKSGRESVKHFGAAGVPGSHAKPHVSSRGKERQRSSKRRHAFRHK
What are the official names of this protein?
60S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL18 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEA_DESHD
Sequence: MKLEDFDFELPEDRIAQHPVEPRDSSRLMVMNRWTGEIEHRVFRELPELLQAGDVLVVNNTRVIPARLIGEKEGTQAKIECLLLTRRDKDVWETLIKPGKRLKAGQTVVFGDGLLRGELLEILPDGNRLVRFNYQGIFEEVLDQLGNMPLPPYITEQLQDKERYQTIYAKESGSAAAPTAGLHFTPELLERLQDKGVEIVEILLHVGLGTFRPVKVENVEEHTMHSEYYRVTPDAAERINRAKSQGRRVIAVGTTASRTLESVAGENGRIEGKEGWTDIYIYPGYTFKILDGLITNFHFPKSTLVMLVSALAGRDQILKAYQIAIAEGYRFYSFGDAMMIL
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_STRCO
Sequence: MIQQESRLRVADNTGAKEILTIRVLGGSGRRYAGIGDVIVATVKDAIPGGNVKKGDVVKAVIVRTVKERRRPDGSYIRFDENAAVILKNDGDPRGTRIFGPVGRELREKKFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: MNHF1_STAAE
Sequence: MNHNVIIVIALIIVVISMLAMLIRVVLGPSLADRVVALDAIGLQLMAVIALFSILLNIKYMIVVIMMIGILAFLGTAVFSKFMDKGKVIEHDQNHTD
What is the function of this protein?
Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.
What are the official names of this protein?
Na(+)/H(+) antiporter subunit F1, Mnh complex subunit F1.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CYSG_SALNS
Sequence: MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLEAGARLTVNALTFIPQFTVWANEGMLTLVEGPFDETLLDSCWLAIAATDDDTVNQRVSDAAESRRIFCNVVDAPKAASFIMPSIIDRSPLMVAVSSGGTSPVLARLLREKLESLLPQHLGQVARYAGQLRARVKKQFATMGERRRFWEKFFVNDRLAQSLANADEKAVNATTERLFSEPLDHRGEVVLVGAGPGDAGLLTLKGLQQIQQADIVVYDRLVSDDIMNLVRRDADRVFVGKRAGYHCVPQEEINQILLREAQKGKRVVRLKGGDPFIFGRGGEELETLCHAGIPFSVVPGITAASGCSAYSGIPLTHRDYAQSVRLVTGHLKTGGELDWENLAAEKQTLVFYMGLNQAATIQEKLIAFGMQADMPVALVENGTSVKQRVVHGVLTQLGELAQQVESPALIIVGRVVGLRDKLNWFSNH
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: MRAY_VIBCH
Sequence: MIIWLAELLQPYFSFFRLFEYLSFRAIVSILTALGISLWMGPRMIKRLQMLQIGQVVRNEGPESHFSKRGTPTMGGVMILAAITITVLLWADLTNPYVWAVLAVLLGYGAVGFVDDYRKVVRKNTDGLIARWKYFWQSAIALVVAFALYAHGQDTAATQLVVPFFKDVMPQLGLMYIVLTYFVIVGTSNAVNLTDGLDGLAIMPTVLVAAGFAAIAWATGNVNFANYLHIPYIPHSSELVVVCTAMVGAGLGFLWFNTYPAQVFMGDVGALALGGALGTIAVLVRQEFVLVIMGGVFVMETLSVILQVGSYKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISIVLVLIGLATLKVR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.