PharMolix/UniProtQA huggingface dataset:
Protein: GSTA_ECOLI
Sequence: MKLFYKPGACSLASHITLRESGKDFTLVSVDLMKKRLENGDDYFAVNPKGQVPALLLDDGTLLTEGVAIMQYLADSVPDRQLLAPVNSISRYKTIEWLNYIATELHKGFTPLFRPDTPEEYKPTVRAQLEKKLQYVNEALKDEHWICGQRFTIADAYLFTVLRWAYAVKLNLEGLEHIAAFMQRMAERPEVQDALSAEGLK
What is the function of this protein?
Catalyzes the conjugation of reduced glutathione (GSH) to a wide number of exogenous and endogenous hydrophobic electrophiles.  Shows activity toward 1-chloro-2,4-dinitrobenzene (CDNB) and ethacrynic acid.  Also possesses thiol:disulfide oxidoreductase activity, using GSH to reduce bis-(2-hydroxyethyl) disulfide (HEDS).  Has a low level of glutathione-dependent peroxidase activity toward cumene hydroperoxide.  Is important for defense against oxidative stress, probably via its peroxidase activity.
What are the official names of this protein?
Glutathione S-transferase GstA, GST B1-1.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Beta family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_KORVE
Sequence: MSEPKYKRILLKLSGEALAQGEQGFGVDPTRVHEIAAEIAEVHRLGVDIGVVVGGGNFFRGVAEQAKDMDRVSADHMGMLATVMNSLAVQDALEKQNVQCRVMSAIEIFQVAEPFIRRRAMRHLEKGRVVIFAAGTGNPYFSTDTAASLRAAEIKADVIMKATKVDGIYDADPHKVADATMFAQITYMDVLKKGLRVMDATAISLCQENRLPIVVFNLNERGNIQRVVMGEAVGSLVSA
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_BUCAP
Sequence: MNSSIFNKLKSLRNRYEEIEIMLSQKDTISNQEKFKNLSKEYLQISEIVKNFIKWEKLETDIKNINLLFNDVEMHDIAQEELFIVKKQKKKLEEKIKILLLPVDPNDQHSCFIEIRAATGGDESSIFAGELFRMYTRYAENYMWKTEIMSSSENERGGFKEIIAKVTGKGACGRLKFESGGHRVQRVPETESQGRIHTSTCTVAIMPVRPKTKKEEIKVSDLKIDTFRSSGAGGQHVNTTDSAIRITHIPSGNVVECQDERSQHKNKAKALSILSARVYADKLAKSQKENSSMRRILLGTGERSDRNRTYNFAQNRITDHRINLTIYKLNEVLQGKLDLLIDPIMQEYQADMLSSLSEFKL
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_GRAFK
Sequence: MQRDTQVFDLIAKEKERQLNGLELIASENFVSEAVLEAAGSVLTNKYAEGYPGKRYYGGCEVVDQVEQLAIDRLKELFNAEYANVQPHSGSQANTAVFHTVMKPGDKFLGFDLSHGGHLTHGSPVNFSGKLYNPVFYGVDKETGLIDYDAVAEIAEKEKPKMIIAGASAYSREIDYKRFREIADSVGAILVADMAHPAGLIAKGLISDPLPHCHIVTSTTHKTLRGPRGGIILMGKDFENPFGEKLKNGNLKKMSTMLNSGIFPGNQGGPLEHIIAAKAIAFGEALTDEFLHYTVQVKKNAEKLAQAFVEKDYKVISGGTDNHMMLIDLRNKNVSGKEAEEALSKADITVNKNMVPFDDKSPFVTSGIRIGTPAVTTRGLQENDMNKIVDLIDRVITNIENDTELEAVKKEVNSMMSGRPLFVA
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TR112_HUMAN
Sequence: MKLLTHNLLSSHVRGVGSRGFPLRLQATEVRICPVEFNPNFVARMIPKVEWSAFLEAADNLRLIQVPKGPVEGYEENEEFLRTMHHLLLEVEVIEGTLQCPESGRMFPISRGIPNMLLSEEETES
What is the function of this protein?
Acts as an activator of both rRNA/tRNA and protein methyltransferases (PubMed:25851604, PubMed:18539146, PubMed:20308323, PubMed:25851604, PubMed:31328227, PubMed:31636962, PubMed:31061526).  Together with methyltransferase BUD23, methylates the N(7) position of a guanine in 18S rRNA (PubMed:25851604).  The heterodimer with N6AMT1/HEMK2 catalyzes N5-methylation of ETF1 on 'Gln-185', using S-adenosyl L-methionine as methyl donor (PubMed:18539146, PubMed:31636962, PubMed:31061526).  The heterodimer with N6AMT1/HEMK2 also monomethylates 'Lys-12' of histone H4 (H4K12me1) (PubMed:31061526).  The heterodimer with ALKBH8 catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA species (PubMed:20308323).  Together with methyltransferase THUMPD3, catalyzes the formation of N(2)-methylguanosine at position 6 in a broad range of tRNA substrates and at position 7 of tRNA(Trp) (PubMed:34669960).  Involved in the pre-rRNA processing steps leading to small-subunit rRNA production (PubMed:25851604).  Together with methyltransferase METTL5, specifically methylates the 6th position of adenine in position 1832 of 18S rRNA (PubMed:33428944, PubMed:35033535, PubMed:31328227).
What are the official names of this protein?
Multifunctional methyltransferase subunit TRM112-like protein, tRNA methyltransferase 112 homolog.
What is the protein family that this protein belongs to?
Belongs to the TRM112 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Cytoplasm, perinuclear region. Note=Localizes to a polarized perinuclear structure, overlapping partially with the Golgi and lysosomes (PubMed:25851604).
Protein: GATC_BURCH
Sequence: MALTLTDVKRIAHLARLEMADADAEHMLGQLNEFFGLVEQMQAVDTAGIAPLAHPIEQIQEVAQRLRDDAVTEVVNRDDNQRPAPAVQDGLYLVPKVIE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: FDB1_FUSPC
Sequence: MSSIRLPPPVVIPESQSTVDVYIIDTTSYMSMVPASSFVEPLVSGFETLNAGSYAFLIEHTSSKPSKHDTMVFDLGVRKDWEHLPDTFVAAVKEEGWSIDVQTDVASILRDNGQDLKSVGAIIWSHWHFDHVGDPQTFPSSTDLIVGPGFKQGVMPGWPTAKDSHVNETAWQGRKLIEIDFSGEAALDIGRFQAYDFYGDGSFYLLNSPGHAVGHMSALARTTADPPSFMLLGGDIAHHCGEFRPSPYTPLPNMITPNPLSNTLLACPGRLFLSIHPWKDPERPFFDPTVGPGWHDEGVLAKDSIDKLIEADAYDNIFPVVAHDMTLVGTVDLYPNKANNWMSRGWKEDTRWGFCGDFTPLDEEMVARNGQVEVLEGHHEVRDSAQDPKVTSIVHMESTDVDKKAKLHDPSFV
What is the function of this protein?
Gamma-lactamase; part of the Fusarium detoxification of benzoxazolinone cluster involved in the degradation of benzoxazolinones produced by the host plant (PubMed:26296598, PubMed:25727347, PubMed:26828593).  Maize, wheat, and rye produce the 2 benzoxazinone phytoanticipins 2,4-dihy-droxy-7-methoxy-1,4-benzoxazin-3-one (DIMBOA) and 2,4-dihydroxy-1,4-benzoxazin-3-one (DIBOA) that, due to their inherent instability once released, spontaneously degrade to the more stable corresponding benzoxazolinones, 6-methoxy-2-benzoxazolinone (MBOA) and 2-benzoxazolinone (BOA), respectively (By similarity).  The first step in the detoxification of benzoxazolinones involves the hydrolysis of the cyclic ester bond of benzoxazolinones by the gamma-lactamase FDB1 to aminophenols (PubMed:26296598).  FDB1 is able to convert BOA into 2-aminophenol (2-AP), as well as MBOA into 5-methoxy-2-aminophenol (2-AMP) (PubMed:26296598, PubMed:25727347).  The N-malonyltransferase FDB2 then metabolizes aminophenols via N-malonylation to non-toxic malonamic acids (PubMed:26296598).  FDB2 converts 2-AP into N-(2-hydroxyphenyl) malonamic acid (HPMA) and 2-AMP into N-(2-hydroxy-4-methoxyphenyl) malonamic acid (HMPMA) (PubMed:26296598).  The cluster contains also 2 transcription factors (FDB3 and FPSE_08121), an aldo-keto reductase (FPSE_08125) that possibly associates with a ketone component of BOA and MBOA degradation, an esterase (FPSE_08126), an acyl-CoA transferase (FPSE_08120), a solute carrier protein (FPSE_08119) and a transmembrane transporter (FPSE_08127) proposed to shuttle metabolites of benzoxazolinone degradation (Probable).
What are the official names of this protein?
Gamma-lactamase FDB1, Fusarium detoxification of benzoxazolinone cluster protein 1, FDB cluster protein 1.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily.
Protein: NFYB2_ARATH
Sequence: MGDSDRDSGGGQNGNNQNGQSSLSPREQDRFLPIANVSRIMKKALPANAKISKDAKETMQECVSEFISFVTGEASDKCQKEKRKTINGDDLLWAMTTLGFEDYVEPLKVYLQRFREIEGERTGLGRPQTGGEVGEHQRDAVGDGGGFYGGGGGMQYHQHHQFLHQQNHMYGATGGGSDSGGGAASGRTRT
What is the function of this protein?
Component of the NF-Y/HAP transcription factor complex (By similarity).  The NF-Y complex stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters (By similarity).
What are the official names of this protein?
Nuclear transcription factor Y subunit B-2, AtNF-YB-2, AtNF-YB2, Transcriptional activator HAP3B.
What is the protein family that this protein belongs to?
Belongs to the NFYB/HAP3 subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GCSP_ECO8A
Sequence: MTQTLSQLENSGAFIERHIGPDAAQQQEMLNAVGAQSLNALTGQIVPKDIQLATPPQVGAPATEYAALAELKAIASRNKRFTSYIGMGYTAVQLPPVILRNMLENPGWYTAYTPYQPEVSQGRLEALLNFQQVTLDLTGLDMASASLLDEATAAAEAMAMAKRVSKLKNANRFFVASDVHPQTLDVVRTRAETFGFEVIVDDAQKVLDHQDVFGVLLQQVGTTGEIHDYTALISELKSRKIVVSVAADIMALVLLTAPGKQGADIVFGSAQRFGVPMGYGGPHAAFFAAKDEYKRSMPGRIIGVSKDAAGNTALRMAMQTREQHIRREKANSNICTSQVLLANIASLYAVYHGPVGLKRIANRIHRLTDILAAGLQQKGLKLRHAHYFDTLCVEVADKAGVLARAEAAEINLRSDILNAVGITLDETTTRENVMQLFSVLLGDNHGLEIDTLDKDVAHDSRSIQPAMLRDDEILTHPVFNRYHSETEMMRYMHSLERKDLALNQAMIPLGSCTMKLNAAAEMIPITWQEFAELHPFCPPEQAEGYQQMIAQLADWLVKLTGYDAVCMQPNSGAQGEYAGLLAIRHYHESRNEGHRDICLIPASAHGTNPASAHMAGMQVVVVACDKNGNIDLTDLRAKAEQAGDNLSCIMVTYPSTHGVYEETIREVCEVVHQFGGQVYLDGANMNAQVGITSPGFIGADVSHLNLHKTFCIPHGGGGPGMGPIGVKAHLAPFVPGHSVVQIEGMLTRQGAVSAAPFGSASILPISWMYIRMMGAEGLKKASQVAILNANYIASRLQDAFPVLYTGRDGRVAHECILDIRPLKEETGISELDIAKRLIDYGFHAPTMSFPVAGTLMVEPTESESKVELDRFIDAMLAIRAEIDQVKAGVWPLEDNPLVNAPHIQNELVAEWAHPYSREVAVFPAGVADKYWPTVKRLDDVYGDRNLFCSCVPISEYQ
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: PSBD_CUSEX
Sequence: MTIALGKLTKEEKDLFDTMDDWLRRDRFIFVGWSGLLLFPCAYFALGGWFTGTTFVTSWYTHGLASSYLEGCNFLTAAVSTPANSLAHSLLFLWGPEAQGDFTRWCQLGGLWTFVALHGAFGLIGFMLRQFELARSVQLRPYNAIAFSAPIAVFVSVFFIYPLGQSGWFFAPSFGVAAIFRFIRFFQGFHNWTLNPFHMMGVAGVLGAALLCAIHGATVENTLFEDGDGANTFRAFNPTQSEETYSMVTANRFWSQIFGVAFSNKRWLHFFMLFVPVTGLWMSALGVVGLALNLRAYDFVSQEIRAAEDPEFETFYTKNILLNEGIRAWMAAQDQPHENLIFPEEVLPRGNAL
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.  D2 is needed for assembly of a stable PSII complex.
What are the official names of this protein?
Photosystem II D2 protein, PSII D2 protein, Photosystem Q(A) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid membrane; Multi-pass membrane protein.
Protein: RL31B_PARXL
Sequence: MKEGIHPDYREVLFIDVSNDFKFVTRSTIQTRETAEFEGKTYPLAKIEVSSESHPFYTGQQKIMDTAGRVEKFRNKFGSRATGKVAAK
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: SYT3_ARATH
Sequence: MGFFTSVLGIIGFVIGIPIGLILGFFVLIYSQPSHQEYPPARPLVETSISVLLDLLPDIPLWMKNPDYERVDWFNKFISYMWPYLDKAVCGIIRSSVQPLFADYIGTFCIESIEFENLSLGTLPPTVHGVKFYETNEKELLFEPSIKWAGNPNIVLVLKVLSLRIRVQLVDLQFFAIVRVALKPLLPTFPCFGMVVVSLMEKPHVDFGLKVLGGDLMSIPGLYRYVQETIKRQVSSMYHWPQVLEIPILDSSTASVKKPVGLLHVSILRARNLLKKDLLGTSDPYVKLSLTGEKLPAKKTTIKKRNLNPEWNEHFKLIVKDPNSQVLQLEVFDWDKVGGHDRLGMQMIPLQKINPGERKEFNLDLIKNSNVVMDSGDKKKRGRLEVDLRYVPFREESIKRRKESREEKSSEDDDFLSQAGLLSVAVQSAKDVEGKKKHSNPYAVVLFRGEKKKTKMLKKTRDPRWNEEFQFTLEEPPVKESIRVEVMSKGTGFHFRSKEELGHVDINLDDVVDNGRINQKYHLINSRNGIIHIEIRWTTS
What is the function of this protein?
May be involved in membrane trafficking.
What are the official names of this protein?
Synaptotagmin-3, NTMC2T1.3, Synaptotagmin C.
What is the protein family that this protein belongs to?
Belongs to the synaptotagmin family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: FOLD_FUSNN
Sequence: MLMDGKELARDIKVKIKAEIDNIKKIHNINPMVATILVGDDPASQVYLNSQVKSYQDLGIGVQKYFFSEEISEAYLLNLIDKLNKDTEVDGIMINLPLPPQINATKVLNSIKLIKDVDGFKAENLGLLFQNNEGFTSPSTPAGIMALIEKYNIDLEGKDVVVVGSSNIVGKPIAALILNSRGTVTICNIYTKNLAEKTKNADILISAVGKAKLITEDMVKEGAVVIDVGINRVNGKLEGDVDFENVQKKASHITPVPGGVGALTVAMLLSNILKSFKANRGII
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: RSMG_MARMS
Sequence: MTHFDTIQKGAQQMGAALSDETIQTLVKYLAMLEKWNKAYNLTAIRDVEQMISLHLLDSLATLPYITGDNIIDVGTGPGLPGMVLAICYPEKRFTLLDSNGKKTRFLTQVKMELGIHNATVANERVEKHSHQGEYDHVISRAFASLQDMINWTLPLPKETGNFLAMKGVYPSEEIAALPKEVGLVSVEPLNVPNVQAERHMVVMTRKG
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2643_VIBC3
Sequence: MSCYCGNTQPYSQCCEPIHLNPHSAQVPEQLMRARFSAHILKNVEFVIETYHPSCQASNERDAISESVHSHWLRLEIISTQMGATPNEGFVHFKAFLDQEGKVFCLEERSRFLKENNCWFYIDGEFPAAIKQGRNDPCACGSGKKYKKCCG
What are the official names of this protein?
UPF0225 protein VC0395_A1443/VC395_1967.
What is the protein family that this protein belongs to?
Belongs to the UPF0225 family.
Protein: PDXA_ECOLI
Sequence: MVKTQRVVITPGEPAGIGPDLVVQLAQREWPVELVVCADATLLTNRAAMLGLPLTLRPYSPNSPAQPQTAGTLTLLPVALRAPVTAGQLAVENGHYVVETLARACDGCLNGEFAALITGPVHKGVINDAGIPFTGHTEFFEERSQAKKVVMMLATEELRVALATTHLPLRDIADAITPALLHEVIAILHHDLRTKFGIAEPRILVCGLNPHAGEGGHMGTEEIDTIIPVLNELRAQGMKLNGPLPADTLFQPKYLDNADAVLAMYHDQGLPVLKYQGFGRGVNITLGLPFIRTSVDHGTALELAGRGKADVGSFITALNLAIKMIVNTQ
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYSY2_BACSH
Sequence: MKQYKDLCRHVLEHGEKKGDRTGTGTISTFGYQMRFHLQEGFPMLTTKKLHFKSIAHELLWFLKGDTNVRYLQENGVRIWNEWADENGELGPVYGSQWRSWRGADGETIDQISRLIEDIKTNPNSRRLIVSAWNVGEIDKMALPPCHCLFQFYVSDGKLSCQLYQRSADVFLGVPFNIASYALLTMMIAHVTGLEPGEFIHTFGDVHIYQNHIEQVNLQLTRDVRPLPKLRFAREIDSIFNFAFEDFIIEDYDPHPHIKGAVSV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase 2, TS 2, TSase 2.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_BORBU
Sequence: MKIGRDELVFETGFMAKQANGSVLATYGGSSVLATVCCSSNVREDLDFVPLSVEYNEKYYAAGKIPGGFIKREGKPKDKEILVSRLIDRPMRPLFDKRFGREIQVIPTTLATDQLNPPDIVGMNAAFTAVFLSDIPFNGPIAAVRMVYLNGKFIVNPSFEEIHDSDLDIVVAGSLNGITMVEGGANEVGEDILLSAIDGAHEYIKQICNAQKEFLDIVGKKEKLPLAFEEKIFEFKDELRDFVYADLKEACFVKGKLNRDKAITLLRNKSYEYFSSLEKLTDSNESLFHKAFDDFEKEIVRSSILNDNIRTDGRTPNEIRDIISEVDILSRTHGSALFTRGETQALAVTTLGTSIDEQIMDDIDGDKRLNFMLHYNFPPFSVGETGRLMTGRREIGHGHLAQRALESMVPGKNDFPYTIRVVSEVLESNGSSSMATVCAGSMSLMSAGVPVKGQVAGIAMGLISEGDKYVVLSDILGEEDHLGDMDFKVAGTKNGITGFQMDIKIENVTKDLMRDALEQARIGRIHILSIMNTVISNSRVGISKYAPKIVQLQIDIDKISLVIGSTGKTVKAITDEFEVKVQIEQNGKIILFGDDDFKMQKAKERIESIVREPKVGEIYEGTVKKINSFGAFIELTPAKEGFLSTRLKPRDSKYGSGRFGNSNRYSRFGGGGENIRGNAGLVRPPKLEEGQRIKVKIIDIDKFGKIDLEIVRDKDY
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_METEP
Sequence: MGKPATPRALPENEAKAVARMLRVSPQKLNLVAALIRGKKVDTALADLEFSRKRIARDVKKCLESAIANAENNHDLDVDDLVVSQAFVGKALVLKRFHARARGRGARILKPFANLTIVVREVRAEAA
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RK32_PHATC
Sequence: MAVPKKRTSKSKKNARKANWKRKGYKAAQKSLSLAKSMLKGKTTSFVYSIYVDDE
What are the official names of this protein?
50S ribosomal protein L32, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y956_HELPJ
Sequence: MEKAYKLLSVQENISHKKAKALIDSGLVSIGGQKLMVARKELPQNTRFSVQKVEKPSVIFEDENILALFKPPFIESYDLVSFFKGWALLHRLDKETSGVILLVKENSEFHLKAKKAFKDRAVKKEYLAIVQGIIEEEREINAPILTIKTTKAFSKISKKGQEAVTIITPLKIINKKTLLKVGIKTGRTHQIRVHLKHINHPIIGDTLYNNEPSSAKRLMLHAHKIALLGYEFEAIAPKEFEI
What are the official names of this protein?
Uncharacterized RNA pseudouridine synthase jhp_0890, RNA pseudouridylate synthase, RNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RluA family.
Protein: CRTO_STAAM
Sequence: MKTMKKYIKTAFFCSMYWLIVQLNIANLGTRIPDKYFRQKYIIFKSFNFEKHGKFWNKWFYVRKWKHKILDGHQLNQNIYDQRHLMTINTDEIEKMIIETKRAELIHWISILPVIIFNKGSRLVKYINIFYAMIANVPIIIVQRYNRPRLTQLLRILKRRGERHD
What is the function of this protein?
Catalyzes the acylation of glycosyl-4,4'-diaponeurosporenoate, i. e.  the esterification of glucose at the C6'' position with the carboxyl group of the C(15) fatty acid 12-methyltetradecanoic acid, to yield staphyloxanthin.  This is the last step in the biosynthesis of this orange pigment, present in most staphylococci strains (By similarity).
What are the official names of this protein?
Glycosyl-4,4'-diaponeurosporenoate acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the acyltransferase CrtO family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: YFS2_SCHPO
Sequence: MLGQGLIFISLAFVAHALEIPISCAVSHNEQTEIFPHGTIDIPEMTFRPSDSQIDWSNLSHSDFVQCGVYEDSTNTWLAGASKYKIDEIKTLPKVPRDHYIILCDSSESNEIAKFTQVVHSFDFSSDSESAVVEQLHPSSPIPILTTAVRKKGSRPSKPQKEKQGNKQGSKTEESPNVDEDELESEPEEKTFFQKYGLYLIPILFLIIMSGNNANQQAANTAK
What are the official names of this protein?
Uncharacterized protein C19D5.02c.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Note=Localizes to the nuclear rim.
Protein: RAPZ_ECOLU
Sequence: MVLMIVSGRSGSGKSVALRALEDMGFYCVDNLPVVLLPDLARTLADREISAAVSIDVRNMPESPEIFEQAMSNLPDAFSPQLLFLDADRNTLIRRYSDTRRLHPLSSKNLSLESAIDKESDLLEPLRSRADLIVDTSEMSVHELAEMLRTRLLGKRERELTMVFESFGFKHGIPIDADYVFDVRFLPNPHWDPKLRPMTGLDKPVAAFLDRHTEVHNFIYQTRSYLELWLPMLETNNRSYLTVAIGCTGGKHRSVYIAEQLADYFRSRGKNVQSRHRTLEKRKP
What is the function of this protein?
Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ.  When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E.  Consequently, GlmZ is inactivated and unable to activate GlmS synthesis.  Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.
What are the official names of this protein?
RNase adapter protein RapZ.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family. RapZ subfamily.
Protein: EFTS_PELUB
Sequence: MSDIEKVKQLREATGAGFKDCNLAIKESGGDLDKAVEILRVKGISKASKKMSRDAKEGVIATSGDENKISIIEINCETDFVAKNDDFVSFAKELSELNNQNSSDLEKLNKSKMANGETVEDSLVALIAKMGEKITLGKAKTFSQPGSKNFNYLHTVVKDNLSKLSVITSLETSNDSEDVKAFGKQLSMHIAASNPLALSSDLIDKDLLQKEQDLVAEELKNSGKPEDIAQKISLGKMNKFKEENALLTQAWVMEPKKKVQDIIKELNIPDLKINNFLRIKIGE
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_FRATN
Sequence: MSKVCIVTGKRPATGNNVSHAQNKTKRRFLPNLHAHRFWVESENRYIKLRVSSKGMRIIDKKGIDTVLSDLRAQGHKI
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: COBS_LACP7
Sequence: MKWLNSLWIAFSMYSKIRVPMKEWEESSMRYAICFFPLIGAVIGGVFFLTFQIGHLLKLGDILIAALLTSIPILISGGIHMDGYCDTMDAISSYQSKERRLEILKDPHSGAFAIIRSGVYFLLYFGMVSVLTLKSSIIIAIFFVVSRALSGLAVVQFKTAKSNGLVATFQQAAHKRKVTISMVIYLVITVIGMLLVSPILTVVGMLTALLCFIRYKKLAYQLFGGTTGDLAGYFLVRCELMAGLAVVIAEGVIIYGTGHWW
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.