PharMolix/UniProtQA huggingface dataset:
Protein: YQGF_TRIV2
Sequence: MTKYISALGLDVGRKRVGVAGCDRTGLIATGITTVERTSFDRDVQQIQNIVNERQVQVLVVGLPYSMDGSLGFQARQVQKFTSRLAKALQLPVEYVDERLTSFQAEQMLIAENVSPSRNKGLIDRKAAALILQQWLDIRRTNAQSSVAVEY
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VGA9_ALHV1
Sequence: MKMLGEPEFKENILYYSFLNELFLILIRNGFSCSHAKLILDETRKRGLECSGQFEVISNSVEAPEPESLERIAKTLFTPRPHWGRLVAFLAYLAYLQKNSTEKLFWNDHLKKLKQIVKCHIVPWTLGPRDPKPKQRPFDKLPSAFYFLTAAASCLTLLLLYFRTTQTK
What is the function of this protein?
Suppresses apoptosis in host cell and thus facilitates production of progeny virions.
What are the official names of this protein?
Putative apoptosis regulator A9.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: TRSF_DROVI
Sequence: MDADSSSRSPRDTRRRSRQREKMPYFADEVRERDRVRNLPKLKTTQKRTPTPPRERRSRHERPRSRSRTHSPEQSRCQRRLSRSYVRHRSGSRQKTYSSSCSRRRRSRSRSRSRGRSRTPRIITVPVPVPAAEYSYAYGWPPPRPHFNPMYGALPFGMQPRPLNPYFGAYARPPPFRYRAGPFRPHPRYSYRNDRQAPN
What is the function of this protein?
Member of the regulatory pathway controlling female somatic sexual differentiation, regulated by Sxl.  Activates dsx female-specific splicing by promoting the formation of a splicing enhancer complex which consists of tra, tra2 and sr proteins.
What are the official names of this protein?
Female-specific protein transformer.
What are the subcellular locations of this protein?
Nucleus speckle. Note=Speckled subnuclear compartment.
Protein: TRPR_ECOLI
Sequence: MAQQSPYSAAMAEQRHQEWLRFVDLLKNAYQNDLHLPLLNLMLTPDEREALGTRVRIVEELLRGEMSQRELKNELGAGIATITRGSNSLKAAPVELRQWLEEVLLKSD
What is the function of this protein?
This protein is an aporepressor.  When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription.  The complex also regulates trp repressor biosynthesis by binding to its regulatory region.
What are the official names of this protein?
Trp operon repressor.
What is the protein family that this protein belongs to?
Belongs to the TrpR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG040_VACCA
Sequence: MIALLILSLTCSASTYRLQGFTNAGIVAYKNIQDDNIVFSPFGYSFSMFMSLLPASGNTRIELLKTMDLRKRDLGPAFTELISGLAKLKTSKYTYTDLTYQSFVDNTVCIKPSYYQQYHRFGLYRLNFRRDAVNKINSIVERRSGMSNVVDSNMLDNNTLWAIINTIYFKGIWQYPFDITKTRNASFTNKYGTKTVPMMNVVTKLQGNTITIDDKEYDMVRLPYKDANISMYLAIGDNMTHFTDSITAAKLDYWSFQLGNKVYNLKLPKFSIENKRDIKSIAEMMAPSMFNPDNASFKHMTRDPLYIYKMFQNAKIDVDEQGTVAEASTIMVATARSSPEKLEFNTPFVFIIRHDITGFILFMGKVESP
What is the function of this protein?
Prevents cell to cell fusion via its interaction with A56 protein.  The A56-K2 complex associates with components of the entry fusion complex (EFC) presumably to avoid superinfection and syncytium formation (By similarity).
What are the official names of this protein?
Superinfection exclusion protein, Protein K2, Serine proteinase inhibitor 3.
What is the protein family that this protein belongs to?
Belongs to the serpin family. Orthopoxvirus OPG040 subfamily.
Protein: SECM_CROS8
Sequence: MPGIFTRWRQFGRRYFWPHLLLGMVAASLGLPALNNNAEPAAPAEASTSHTGTLRSFDSLALISETSRRSASFGVDYWQQHAIRTVIRHLSFAMAPQALPMAMEESLPLNAQHLALLDTLSAMLTQDLQPAAAQVQPAPRLLPPLSFTVSAWIRQVQGIRAGPRLLA
What is the function of this protein?
Regulates secA expression by translational coupling of the secM secA operon.  Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation.
What are the official names of this protein?
Secretion monitor.
What is the protein family that this protein belongs to?
Belongs to the SecM family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Periplasm. Note=The active form is cytosolic, while the periplasmic form is rapidly degraded, mainly by the tail-specific protease.
Protein: CYF_PHAAO
Sequence: MQNRKTFSWVKEQMTRSIYVSIMIYVITRASISNAYPIFAQQVYENPREATGRIVCANCHLANKPVDIEVPQAVLPDTVFEAVVRIPYDMQLKQVLANGKKGALNVGAVIILPEGFELAPPDRISPEIKEKMGNLSFQFYRPNKRNILVIGPVPGQKYSEIVFPILSPDPATKKDVHFLKYPIYVGGNRGRGQIYPDGNKSNNTVYNATSAGIVSRIARKEKGGYEITIVDASEGRQVVDIIPPGPELLVSEGESIKLDQPLTSNPNVGGFGQGDTEIVLQDPLRVQGLLFFLASVILAQIFLVLKKKQFEKVQLYEMNF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome f family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: ZAPD_PARXL
Sequence: MILYEYPFNERIRTLLRLEDLFERFTFFLTQEDAREHHVALTTLFEISEVAGRADLKSDLMKELERQRQTLAPFRGNPGIEQNALEAVLGEIEQTLSGLSQMQGKTGQHLADNEWLASIRSRAIIPGGTCKFDLPSYYAWQQLHPDQRRQDIAKWVTPLLPLRDAATIVLRLARESGQASKVMAMQGSYQQMLSGRSYQLMQVRVAPELRVIPEASANKYMLWVRFTVQDGDLRPRAVDVDVPFQLTLCSL
What is the function of this protein?
Cell division factor that enhances FtsZ-ring assembly.  Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
What are the official names of this protein?
Cell division protein ZapD, Z ring-associated protein D.
What is the protein family that this protein belongs to?
Belongs to the ZapD family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to mid-cell in an FtsZ-dependent manner.
Protein: CCD43_CHICK
Sequence: MAAPCVEAAGPGGFGAWLAARLEALGLDRAVYGAYIAGLLREEESEEERLEALRGVLAACLEEDLLNDVCREVVEKWSESQIVDAKEKKEDEVQAIASMMEKQARITVKPKEISQEEKQRKAALLAQYANVTDEEDGDDEQDSSTATAVNIGSEKSLFRNTNVEDVLNARKLERELLRDEFQKKKEQDKLQREKDKLAKQERKEKEKKRTQKGERKR
What are the official names of this protein?
Coiled-coil domain-containing protein 43.
What is the protein family that this protein belongs to?
Belongs to the CCDC43 family.
Protein: RS11_ESCF3
Sequence: MAKAPIRARKRVRKQVSDGVAHIHASFNNTIVTITDRQGNALGWATAGGSGFRGSRKSTPFAAQVAAERCADAVKEYGIKNLEVMVKGPGPGRESTIRALNAAGFRITNITDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: LEUC1_PYRAB
Sequence: MGMTIAEKILADHSEREEVKPGEIVMAKLDFVFGNDVTMPLAIKKFRELGVKRVFDRERIAIVLDHFTPNKDIKSAEQCKSSREFAKEMGIKWFFEGGSVGVEHCLLPELGLVLPGDLIIGADSHTCTYGALGAFATGVGSTDLAVAMATGEAWFRVPETMKFIYEGELQPYVTGKDLILHTIGDIGVNGALYKVMEFSGSVIEELSVEQRMTMSNMAIEAGAKTGIIEPDKKTLDYVKERAKRKFKVYKSDEDAKYYKVIEYDVTNWEPVVAFPHLPENTVPISKAAKMNIKIDQVFIGSCTNGRIEDLRMAAEILEGQKVAKWVRLIVIPCSPTVYWKALKEGLIEIFLEAGAVIGPPTCGPCLGGHMGVLASGERAVSTTNRNFVGRMGHPKSEVYLANPYVAAASAVLGRIASPEEVVK
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit 1, Alpha-IPM isomerase 1, IPMI 1, Isopropylmalate isomerase 1.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
Protein: ABCGK_DICDI
Sequence: MSNSNNNNNNKKLAISLKNVCRGYGNTKVIDNLNLQIKSGTINCLIGASGSGKTTILRTILGRLIPDSGEVLVFGKRPHDIGGVPGSICGFCPQEGALYYDLTLDHTLNFFSNVHQIPKDKFESKKNEIIKLLDLPQINSRSVGLLSGGQKKRVSLAVALLHSPKLLILDEPTVGIDMEVASNIWSYLRSLANSGVTIIITTHYINEAVGSDNVFLLRDGKILENGAPNYLIERYESQTLEEVFLKLCKRDNAQSIVDSKKNNNNSYFSSQEIIDVESHIVNNNNNNNNNNNNNNYNNNDDEENYNDDIYNDKKPLIGISKEDENNTNGSTNKESGILFRFYKVLLHSVAIGKRKFIQIIRNKVVLSFELLSPSVQVLLYFLAIGGSPKNLEFGVVNLDVGPIGSMYINSLSNTGIFNFHNYNSTTEAIEQIKSGNSFGLLDINAQFSEAILENFMNLSQYNPNGQIDLYMDFTNYQITLIVEQQLALSFETLAKQQANITMNPIKTVTPTVYGNPNSKFIDFLAPGMVCLISFAHAISITSVSFVKEKVDGSLDRLFAYGVRTSSIVFGHFLGHLPLLLVQITVLLLIAIYGFNVPIEGNIALVFLMTVSLAFVGMSLGLVISAVSRVETEAIQLSLGVYFPTLICSGTLWPLQSLPNWFVWFPNILPATHAGNAMRDIMLKGVGLHYKEVWVAFLVVLSWLIFLIFIAVLALNEKDKNLKLSCFKKRK
What are the official names of this protein?
ABC transporter G family member 20, ABC transporter ABCG.20.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y396_MYCPN
Sequence: MGLKKRVSFDWLLKIGIILVLAFLGLFGIIFGSYKLLNDSRLGVVFNGSTTTTVYFLNHKSKDANKELDPTQKKDGNGSGNNTEMITDVNGFLNNIEKSYANSLYAQGFSSVNITKNSHDTSAKELSDKGVFDSSWLVNDGLPSISVTFEQRREEARTRARKRQIDAQVKRNALSAIEHNYKLSLETTDGIVLFDSFDKEFIRNSLTAVVPQTTNTNSALTFEYKLSKNVITKESLHNDFLDFIKSKSLTDSDYNTGNGQKSVEGSGKWFKDKANGSAQNGNKTLVLWKDKEGAVQYVRNIFNVPKGGTDYLTFNEREKNLWDFLHAEGNFSSGDNLFLQKNNNGNSPITKASDITLKNIYYIYAAPTHFSQVATKDNNNKDAADVVAVANSADTRKLRSGDATGFSGLFSNYILAEIRTEDPVAKNGDPVKVNATLQSFLDSNNQRLEHGGNIKFQVANFVNNDGSYVPASYLEASRVKVLLSNGFPETATIAAANTKLVNAPLSNTLARDVSNFASSFIALGVIILLATIALGIRYKLLGLYKALALALSAISSLAFFSAVGGVVDVFSFVGIFFVVAVNIINLITLAELFLRNIKNNASIVESWKLCLKRSFFTMIETHICWLLSALVVIYLSNYQVQQLGTLMAVSAITSYFLNYGLGVILVWLFVSSHSGLEWRFFLYKKDAQALTKTSSNYSILTENNDIQTDFFISKNQHDFFGKKKWSLLFIWLTVLAFGVVMLGLYLGAPQLLGNFLAADIESSTGIMLGVGVISLLYLLYSLPRYGVAYGISYLIALILLAAGLFGAMYLANFIFRIDQSTIQLIIFVYLFWLFFQARIGQTTIWTYCYWFKRSLKDRVFVKNLFNDNVNSQWRLDLIGSSVLILLFIVYAAFNFGGINGTINLVIFYLIAIVALFSVFVNGLPLFSFGLINGWLSPYNYVQIHITLRHKKQMFKEVDQIEEQLISGINSF
What are the official names of this protein?
Uncharacterized protein MG277 homolog.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MSRP_SALHS
Sequence: MKKIRPLTEADVTAESAFFMQRRQVLKALGISAAALSLPSTAQADLFSWFKGNDRPKAPAGKPLEFSQPAAWRSDLALTPEDKVTGYNNFYEFGLDKADPAANAGSLKTEPWTLKISGEVAKPFTLDYDDLTHRFPLEERIYRMRCVEAWSMVVPWIGFPLYKLLAQAQPTSHAKYVAFETLYAPDDMPGQKDRFIGGGLKYPYVEGLRLDEAMHPLTLMTVGVYGKALPPQNGAPIRLIVPWKYGFKGIKSIVSIKLTRERPPTTWNLSAPNEYGFYANVNPHVDHPRWSQATERFIGSGGILDVQRQPTLLFNGYANEVASLYRGLNLRENF
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone SurA and the lipoprotein Pal.  The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase catalytic subunit MsrP.
What is the protein family that this protein belongs to?
Belongs to the MsrP family.
What are the subcellular locations of this protein?
Periplasm. Note=Is attached to the inner membrane when interacting with the MsrQ subunit.
Protein: ALG8_PSEPK
Sequence: MLNMQRLQTVLLQCAGWLLYMSLLMLIALALPADIFDSQSKHFIFLVGAVGIWRYSMGATHFIRGMIFLYGVYPYLRRKVQKMGNATDPSHVYLMVTSFRIEALTTAQVYSSVIREAINCGFPTTVVCSLVEMSDELLVKSLWAKYNPPAHVKLDIVRIAGTGKRDGLAYGFRAISRMLPDENAVVAVIDGDTVLADGVVRKTVPWFKLFPNVGGLTTNEFCEVRGGYIMSEWHKLRFAQRHINMCSMALSKRVLTMTGRMSMFRASVVTNPEFIADVESDSLMHWRLGRFKFLTGDDKSSWFSLMRLGYDTFYVPDAAINTVEHPPEKSFLKASRKLMYRWYGNNLRQNSRALGLGLRRLGLFTSIVLFDQRVSMWTSLLGLTVAVIASLKFGMAFLLVYLLWIGITRLILTIMLLCSGHNVGPAYPLILYYNQIIGALMKIYVFFRLDKQSWTRQPTALKRDLASFQQWFNTWSSRTMTFSAASIFVAVLFMVV
What is the function of this protein?
Possibly a processive enzyme that polymerizes GDP-mannuronic acid.
What are the official names of this protein?
Glycosyltransferase alg8.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y2014_RICFE
Sequence: MVSMKQVERQKLNQKLMRAAATGDIEAVQKLVLRGADIYCRDHQGDTALSLAAGSGYLDILDI
What are the official names of this protein?
Putative ankyrin repeat protein RF_p14.
Protein: MNMA_THET2
Sequence: MKRVLVAMSGGVDSSVAALLLKEAGYEVVGAMMRFWPDLPPPSLEAGKPRAWESCCTPDAAYEARRVADRLGIPFYLLDYREVFEEEIISPFLQDYAQGRTPNPCARCNTFVKFGALLKQARRLGLDYVATGHYVRKEGLALLRGLDPHKDQTYFLWGTPKEALPHLLFPVGGLTKPEVRALAEKAGLPTARRPESQNLCFVAGDLKGFLKERLKPRPGPLVDALTGEVVGEHEGASLYTLGQRKGLGLYKTHLERYVVGVDPERNVVYVGPKEACYFEGLEGEGLNLLAELPEEVEVQVRYRTPPVRAKVESLSPLRLRFAHPVFAVTPGQSAVFYRGERLLGGAVIRRGLYNLAGLEDPRALTFS
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2661_GEOTN
Sequence: MNEPVLFLLLLLAIGVIAKNQSLIIAIAVLLAIKLFGLEARLLPAIQAKGINWGVTVITVAVLAPIATGEIGFKQLIGSLQSASAWIALLFGIFVALIAKGGVMLLASDPHITASLVLGTVIAVSLFHGVAVGPLIGAGIAYVVIKMVEYF
What are the official names of this protein?
UPF0756 membrane protein GTNG_2661.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TECB_CUPXP
Sequence: MKLKGEVALVTGGGAGLGRAIVDRYVAEGARVAVLDKSAAGLEEIRKRHGDAVVGIEGDVRSLDSHREAVARCVETFGKLDCLIGNAGVWDYQTQLADIPDNGISEAFDEMFAIIVKGYILAAKAALPALYKSKGSAIFTVSNAGFYPGGGGVLYTAGKHAVIGLVKQLAHEWGPRIRVNGIAPGGILGSDIRGLKTLGLQDQTIATMPLADMLGPVLPTGRVATAEEYAGAYVFFATRADTVPLTGSVLNIDGGMGVRGLFEASLGAQLDKHFA
What is the function of this protein?
Can transform various dihydrodiols of chlorobenzenes and chlorotoluenes into the respective catechols.
What are the official names of this protein?
Chlorobenzene dihydrodiol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: PRVB_MERBI
Sequence: AFSGILADADVAAALKACEAADSFNYKAFFAKVGLTAKSADDIKKAFFVIDQDKSGFIEEDELKLFLQVFSAGARALTDAETKAFLKAGDSDGDGAIGVDEWAALVKA
What is the function of this protein?
In muscle, parvalbumin is thought to be involved in relaxation after contraction.  It binds two calcium ions.
What are the official names of this protein?
Parvalbumin beta, Parvalbumin isoform B.
What is the protein family that this protein belongs to?
Belongs to the parvalbumin family.
Protein: INA17_ZYGRC
Sequence: MLRVLPTSFKSISTRSAFRACQLSPLTVYCPLKSSQGTDIKSLEDLTKLKSLEGVDPELIRKLINERTIELNVQNELEMLKNLNKQEKMSQEVSLKRFVRPLWVFFLMSSTVYLILHYVWWKLEVVEKEKELQSHVESLEMELDQTLKSQNQNVSSSQNNGNNKTNDKPWYRKWFF
What is the function of this protein?
Component of the INA complex (INAC) that promotes the biogenesis of mitochondrial F(1)F(0)-ATP synthase.  INAC facilitates the assembly of the peripheral stalk and promotes the assembly of the catalytic F(1)-domain with the membrane-embedded F(0)-domain.
What are the official names of this protein?
Inner membrane assembly complex subunit 17.
What is the protein family that this protein belongs to?
Belongs to the INA17 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: DUT_BURPS
Sequence: MKLDLKILDARMRDYLPKYATTGSAGLDLRACLDAPVTLKPGDTALVPTGLAIHLADPGYAALILPRSGLGHKHGIVLGNLVGLIDSDYQGELMISTWNRGQTEFALNPFERLAQLVIVPVVQARFNLVDDFAQSERGAGGFGSTGRG
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: RL16_ALCBS
Sequence: MLQPKRTKFRKVMKGRNRGLAQRGSKVSFGTIGLQATGRGRITARQIEAARRAMTRHIKRGGKIWIRVFPDKPITNKPLEVRMGKGKGSVEYWVAQIQPGKMLYEMEGVSEDVAREAFRLAAAKLPVSTRVVTRTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: BIOB_LYSSC
Sequence: MNFLQVAQEVIDGKIISNEEALAILNSKDDELLQLMDGAFAIRRHYYGKKVKLNMIMNAKSGYCPEDCGYCSQSSKSTAPIEKYPFITKEEILAGAKRAFDNKIGTYCIVASGRGPTRKDVNVVSEAVVEIKEKYGLKVCACLGLLKEEQAQQLKEAGVDRYNHNLNTSERHHSFITTSHTYEDRVNTVEIVKKHGISPCSGAIIGMKETKEDVVNIARALHQLDADSIPVNFLNAIDGTKLEGTKDLNPRYCLKVLALFRYINPTKEIRISGGREINLGCLQPLGLYAANSIFVGDYLTTAGQEANSDYRMLEDLGFEIELTQKQEAAFC
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: SUS1_YEAS1
Sequence: MTMDTAQLKSQIQQYLVESGNYELISNELKARLLQEGWVDKVKDLTKSEMNINESTNFTQILSTVEPKALEMVSDSTRETVLKQIREFLEGIVDTQ
What is the function of this protein?
Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes.  At the promoters, SAGA is required for recruitment of the basal transcription machinery.  It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination.  Within the SAGA complex, participates in a subcomplex required for deubiquitination of H2B and for the maintenance of steady-state H3 methylation levels.  The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket).  TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.  May also be involved in cytoplasmic mRNA decay by interaction with components of P-bodies (By similarity).
What are the official names of this protein?
Transcription and mRNA export factor SUS1.
What is the protein family that this protein belongs to?
Belongs to the ENY2 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Cytoplasm, P-body.
Protein: RPOC1_CHLVU
Sequence: MSTRKSPFFKKAEISLASPKAIEIWTERYFPNGQPINEVTSSETVNYKTLKPEPHGLFCQTIFGPVVDFTCACGKKATKLVKNKKFRGYCPKCGVERTSSRVRRYRLGLIKLKQPVAHSLYVSHRPSPLRLCLGWSTKRLQAVLKAVEFCYLPLIFTTFQSERECFSFFPKSFLLLRSQLTQKNEVFLEPRSSGFNENLSSSFFFKEKKRSKRKTGKVFPLRTSPRLFHKKHQKNRPRLVFNHGVIEARLYGIAYDATWPKVEEFQEFLFYLWEQSFFYESSIPYYAFAKGVKSYKEEIPKREQSYALQTGGLALQQILSHHDSSRFEYDLIYLSKKVSMILEILKENMASLNLDYEDDQKEYKKLLSKVKKLDLLLLKWKRQRELYRDFEVGKTQPAWMILNNLPVLPPGLRPITSIGGLVVASDINSFYRKIIIRNKRMSPRNNLGIFDTTLGGSWLSWCYNLRQVQEAVDELLRTGSVDAGRPLKSLLDGLKGKKGRFRQHLLGKRVDYSGRSVIVVGPKLKLHQCGLPKEMAVELFQPFIIQQLRLQGIVFTVTAAKVLIADRKPIVWSVLGEILKRHPVLLNRAPTLHRLGIQAFLPRLVEGKAILLHPLVCPAFNADFDGDQMAVHVPLSAKTRAEALSLLWSRNQLLAPSSGQPQHLPTQDMVLGFYYLTCSLEKTLKRVDSLVSSRKLFFQSSFFLKKKNEETLKNSIPQNLYFSEFSQVKTAYDIGNLTLHTPIWVKWTSCVQTFVPERHSRLKETLLETRLTFSGQRQTLFIDTCQFFSPSFFFGKKVRFIRTTPGRIFMHWCFFEANAEMSSTPTSKEKKSLEKK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', PEP, Plastid-encoded RNA polymerase subunit beta', RNA polymerase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y052_HAEIN
Sequence: MKSIKGLGKLLLASSILFSSSAFAKTIIKLGHYNSDIHPSHIALQEYFKKTIENETNHKYEIRLYPNNQLGGEDQIVNGLRNGTIEAGITGLLLQNVDPIFGVWEWPYLFKDNQEAKKVLESPIANKIGQKMEKYGIKLLAYGMNGFRVISSNKKLEKFDDFKGLRLRVPLNSLFVDWAKAMNINPQSMPLSEVFTALEQKVIDGQENPYMLIKDSGLYEVQKYIIQSNHIFSPGLLQISLKTWNKIPKEDQIIFEKAAKLYQEKEWELAIKTELEVKDYLAKHGNEIIVPSEAFKNDMVNASKVLYDSFYKKYDWAKDVVQKINEAK
What are the official names of this protein?
Uncharacterized protein HI_0052.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 7 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RL33_BUCA5
Sequence: MAKKAREKIKMISSAGTGHYYTTTKNKRNTPDKLKLKKYDPVIRKHILYNEGKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: X_WHV1
Sequence: MAARLCCQLDPARDVLLLRPFGSQSSGPPFPRPSAGSAASPASSLSASDESDLPLGRLPACFASASGPCCLVVTCAELRTMDSTVNFVSWHANRQLGMPSKDLWTPYIRDQLLTKWEEGSIDPRLSIFVLGGCRHKCMRLP
What is the function of this protein?
Multifunctional protein that plays a role in silencing host antiviral defenses and promoting viral transcription.  Does not seem to be essential for HBV infection.  May be directly involved in development of cirrhosis and liver cancer (hepatocellular carcinoma).  Most of cytosolic activities involve modulation of cytosolic calcium.  The effect on apoptosis is controversial depending on the cell types in which the studies have been conducted.  May induce apoptosis by localizing in mitochondria and causing loss of mitochondrial membrane potential.  May also modulate apoptosis by binding host CFLAR, a key regulator of the death-inducing signaling complex (DISC).  Promotes viral transcription by using the host E3 ubiquitin ligase DDB1 to target the SMC5-SMC6 complex to proteasomal degradation.  This host complex would otherwise bind to viral episomal DNA, and prevents its transcription.  Moderately stimulates transcription of many different viral and cellular transcription elements.  Promoters and enhancers stimulated by HBx contain DNA binding sites for NF-kappa-B, AP-1, AP-2, c-EBP, ATF/CREB, or the calcium-activated factor NF-AT.
What are the official names of this protein?
Protein X, HBx, Peptide X, pX.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus protein X family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Host mitochondrion. Note=Mainly cytoplasmic as only a fraction is detected in the nucleus. In cytoplasm, a minor fraction associates with mitochondria or proteasomes.
Protein: CTHL5_BOVIN
Sequence: METQRASLSLGRWSLWLLLLGLALPSASAQALSYREAVLRAVDQLNEKSSEANLYRLLELDPPPKEDDENPNIPKPVSFRVKETVCPRTSQQSPEQCDFKENGLLKECVGTVTLDQVGSNFDITCAVPQSVGGLRSLGRKILRAWKKYGPIIVPIIRIG
What is the function of this protein?
Exerts a potent antimicrobial activity against Gram-negative and Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus, and fungi.
What are the official names of this protein?
Cathelicidin-5, Antibacterial peptide BMAP-28, Myeloid antibacterial peptide 28.
What is the protein family that this protein belongs to?
Belongs to the cathelicidin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS14Z_MESFL
Sequence: MAKKSLKVKQAKHQKFGVRNYTRCNNCGRPHAVLKKFGICRLCFRKYAYEGQIPGIRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.