PharMolix/UniProtQA huggingface dataset:
Protein: ZIC4_HUMAN
Sequence: MRYKTSLVMRKRLRLYRNTLKESSSSSGHHGPQLTAASSPSVFPGLHEEPPQASPSRPLNGLLRLGLPGDMYARPEPFPPGPAARSDALAAAAALHGYGGMNLTVNLAAPHGPGAFFRYMRQPIKQELICKWLAADGTATPSLCSKTFSTMHELVTHVTVEHVGGPEQANHICFWEECPRQGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFRCEFEGCERRFANSSDRKKHSHVHTSDKPYTCKVRGCDKCYTHPSSLRKHMKVHGRSPPPSSGYDSATPSALVSPSSDCGHKSQVASSAAVAARTADLSE
What is the function of this protein?
Binds to DNA.
What are the official names of this protein?
Zinc finger protein ZIC 4, Zinc finger protein of the cerebellum 4.
What is the protein family that this protein belongs to?
Belongs to the GLI C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YHGB_BACSU
Sequence: MKHTCPVCGFKDWLNRHMIMKAIILMKSARAAVFSSDLMSTRCSTRITHIEPSESIIAYRKNWLAEGCVIFSPECFPKHLQKANRGLRHHLIEQLKQINVHLPS
What are the official names of this protein?
Uncharacterized protein YhgB.
Protein: ATPD_RICAH
Sequence: MNKDNLIKNYAVALFNNAVVDNIQDKIFEEITAINRIITDNFDIREFLFSPIVNKNDKVNAVNSLAKNIKMSTIVQNFLLLLVKNSRTAILSNIVDTYNALLYESKNIKIVRVISANKLQPKEQEWIKSRIEKELNQKTEILFDIDSTIIGGIVIKYDSMLQDYSIKGSLEKITKTLKKVRIAA
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: P5CR_SYNY3
Sequence: MSIQLGIIGGGVMAEAILARLIAEKTYAPEEIIVGEPHGARRDYLQKTYQVRVSPDNQEAANVSEVLLLAVKPQVLDRVLASLAGGANRPLVISILAGVSLQRIQKGFPDHAIIRAMPNTPATVGAGMTAIAANKMVEPDQLAKAKAIFSAVGNVVEVPENLMDAVTGVSGSGPAYVALMIEALADGGVLAGLPRAIAQKLALQTVLGTAELIKETEEHPAQIKDKVTSPGGTTIAGVAVLEKMGFRSAIIEAVRAAYRRSQELGKK
What is the function of this protein?
Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
What are the official names of this protein?
Pyrroline-5-carboxylate reductase, P5C reductase, P5CR, PCA reductase.
What is the protein family that this protein belongs to?
Belongs to the pyrroline-5-carboxylate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_ENT38
Sequence: MMTQWPSPAKLNLFLYITGQRADGYHTLQTLFQFVDYGDTISIEPRQDGEIHLLTPVDDVASEDNLIVRAARLLVQAAANSGRLPEHYGADIGVEKRLPMGGGLGGGSSNAATVLVALNHLWGCGFSQDELATLGLTLGADVPVFVRGHAAFAEGVGEILTPVDPPEKWYLIAHPGVSIPTPVIFNDPELPRNTPVRSIETLLKCEFGNDCEVIARKRFRKVDAALSWLLEYAPSRLTGTGSCVFAEFDTESAARQVLEQAPEWLHGFVARGMNTSPLQQTILAQTEFR
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: H1B_CHITE
Sequence: MSDPAVEVTPAVPVASPAKAKKEKKPKSDKPKKPKAPRTHPPVSEMVVNAVKTLKERGGSSLQAIKKFLVAQYKVDVDKLAPFIKKYLKSAVEKGQLLQTKGKGASGSFKLPAAAKKEKVVKKPTKAAAEKKPKKAAAKPKKAGEKKVKKTIAKKPKAAAATKIKKPVAKTTKKPAAAKPAAKKAAPKPKAAPKPKAAKTETKPKRAAAPKAKKPAAEKKPKAAKKPAAKKA
What is the function of this protein?
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.
What are the official names of this protein?
Histone H1B.
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RF3_SALHS
Sequence: MTLSPYLQEVAKRRTFAIISHPDAGKTTITEKVLLFGQAIQTAGTVKGRGSSQHAKSDWMEMEKQRGISITTSVMQFPYHDCLVNLLDTPGHEDFSEDTYRTLTAVDCCLMVIDAAKGVEDRTRKLMEVTRLRDTPILTFMNKLDRDIRDPMELLDEVENELKIGCAPITWPIGCGKLFKGVYHLYKDETYLYQTGKGHTIQEVRIVKGLNNPDLDAAVGEDLAQQLRDELELVQGASNEFDEELFLAGEITPVFFGTALGNFGVDHMLDGLVAWAPAPMPRQTDTRTVEASEEKFTGFVFKIQANMDPKHRDRVAFMRVVSGKYEKGMKLRQVRTGKDVVISDALTFMAGDRSHVEEAYPGDILGLHNHGTIQIGDTFTQGEMMKFTGIPNFAPELFRRIRLKDPLKQKQLLKGLVQLSEEGAVQVFRPISNNDLIVGAVGVLQFDVVVARLKSEYNVEAIYESVNVATARWVESADAKKFEEFKRKNETQLALDGGDNLTYIAPTMVNLNLTQERYPDVQFRKTREH
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHO4_YEAST
Sequence: MNTLLFKRKGGNCGNESNIVSQGSPSSSNLPESPGTLDEKNLPRLPTPFARSLSTIPSYEQMKRTNKLPDYHLKIVVVGDGAVGKTCLLISYVQGTFPTDYIPTIFENYVTNIEGPNGQIIELALWDTAGQEEYSRLRPLSYTNADVLMVCYSVGSKTSLKNVEDLWFPEVKHFCPSTPIMLVGLKSDLYEADNLSDLVEPSSAESLAKRLGAFAHIQCSARLKENIDEVFETAIHTLLSDSLYAPREPTHTIKNPFKRNTTRSDIDSSTGDTSVSISGTKRLRKNKCIIM
What is the function of this protein?
Plays an important role in cell growth.  Required to keep the uninucleated state.  May be involved in the organization of the cytoskeleton which affects microtubule functions.  Most likely RHO3 and RHO4 of S. cerevisiae regulate partially overlapping but different pathways.
What are the official names of this protein?
GTP-binding protein RHO4.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: RS19_DESOH
Sequence: MPRSLKKGPFVDEKLENKIVIARNTKSSHIIKTWSRRSTVTPEMVGLTFAVHNGKKFIPVFVTENMVGHKLGEFSPTRTFYGHAGSKKSKVR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: PARI_RAT
Sequence: MAVLNQMSVLDMIKAFRRNWRAHCNSERTTLCGPDSMLLALQLSMAENNKQHHGEFTVCLSDVLLTWKYFLHEKLNLPIENMKVVDHYEDIRKTYDDFLKNSNTLDLIDVYKKCSIMTSNCEKHMISSIQLRDFLSGTECAVNDENNPHSPASPVKCSQNDKQVRLLAKKIFLSYLSLLVNSKNDLALAQILNTPDRGLGREAFTNLKHAAREKQLSMFLMATSFIRTLELGGKGYAPPPSDPLWAHVKGLSAFVNFIDKLNEILGEVPNPSLAGGRILSAIRTQLIKGHSSGEPFYKAVEEVVQDLNLRIKNIINSQEGVTVSATNISPVPPKSFAINHDTAYCGRDAVKILLVLLDEDAASAPTRNKAELLYNDQSTAPHGGASVLTLFRSPTQVKSTPVKPLRERIHTSLQAEKNKQMRQTLIRSQFACTYKDDCIMSKSKWNVNSSSKPLSALRLENDVSEGAQPSVGKARLETSSENVHVDRSKDDKGPRKSTKRKLAKSKQPGVREDIHCDQGDELYQPKNVKILKVPSDSHRKAGGKLAPGARGNRCTTKDKLIPGQTKLTRFFML
What is the function of this protein?
Required to suppress inappropriate homologous recombination, thereby playing a central role DNA repair and in the maintenance of genomic stability.  Antagonizes homologous recombination by interfering with the formation of the RAD51-DNA homologous recombination structure.  Positively regulate the poly(ADP-ribosyl)ation activity of PARP1; however such function may be indirect (By similarity).  Binds single-strand DNA and poly(A) homopolymers.
What are the official names of this protein?
PCNA-interacting partner, PARI, Antisense RNA overlapping MCH gene protein, AROM, PARP-1 binding protein, PARP1-binding protein, PARPBP.
What is the protein family that this protein belongs to?
Belongs to the PARI family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes to chromatin in response to S phase arrest but not in mitosis. Targeted to chromatin via its interaction with PCNA (By similarity).
Protein: NRDR_PROMP
Sequence: MQCPTCQNTDSRVLESRSADTGKSVRRRRECLNCSFRFTTYERVETMPISVIKKDGSRELFNKDKLVTGISRACEKTTFSRESIINFVDSIESQIVQDSNKDIKSSQIGELILKGLRKENEVAYIRYASVYRKFNGVKDFVSTLESLKGSSKNELASIL
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: RL18_AZOC5
Sequence: MARDLEALERRKAKVRRAIRAAANGRPRLSVHRTSKHIYAQIIDDAKGETLVAASSLEKDLRSSLKTGADVEAAKAIGKLVAERATAKGVTAVVFDRGAYIYHGRVKALAEGAREGGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: FABZ_CLOP1
Sequence: MMNINEIKEILPHRYPFLLVDKVEEITESKVVAYKNVTINEPFFQGHFPDYPVMPGVLIVEALAQAGAIALLNKEEFKGKTPFFAGIDKVRFKKQVLPGDTLRLEVEIIKLRGSIGFGKATATVDGKIACSGEIMFAIG
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_COXBR
Sequence: MTTITPIMVKELRERTGAAVMACKKALQETNGDMEAAIDLLRKAGDAKAAKRAGKTAAEGVIVIAISKDQKKGFMAEVNSETDFVARDTNFMAFASKVAERGLAEGVSDVAATLALPIEPNSSSTIEDERKALVNRIGENIQIRRVASLSSDGVVGHYSHGGRIGVLLALDVPNPELAKGLAMHVAAFNPQAVSANQVSTEFVEKEKEIFLARAQETGKPANIIEKMVKGQVEKLLKEVSLEGQSFVKDPEKLVGDLLKAEKAKVLAFLRFEVGEGVEKESQNFADEVMAQVQGNR
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4103_PSEPF
Sequence: MLIPYDALEVDTLTRLIEDFVTRDGTDNGDDTPLETRVLRVRQALTKGQALIVFDPESEQCQLMLKHDVPKHLFD
What are the official names of this protein?
UPF0270 protein Pfl01_4103.
What is the protein family that this protein belongs to?
Belongs to the UPF0270 family.
Protein: SARD4_ARATH
Sequence: MAALPVFIPAESFPSILSHETLINHFRTNLPKHSSTITSPVRQNYTVSSPSSLLLMPSWSSSSSLPYMGVKLVTYFPHNSSQNLPGIHGSYTLFSSTTGQTLATMDGTVLTLYRTSSVSGLGSKILARDDSQVLIMVGSGALAPHLIKSHLAAKPSLRRVIIWNRTPQRAQELAETLSKDPQHKEISFDSHDSLDQIIPLGDIISCATNSTVPLVKGEFLKPGTHLDLVGSFSHEMKECDDNAIQRGSVFVDNDTAMIEAGELAGAFERGVIKREDICGNLVELIKGDKEGRKSSTDITVFKSVGSGTVDLLTAQLVHETYLSRC
What is the function of this protein?
Involved in the biosynthesis of pipecolate (Pip), a metabolite that orchestrates defense amplification, positive regulation of salicylic acid (SA) biosynthesis, and priming to guarantee effective local resistance induction and the establishment of systemic acquired resistance (SAR).  Converts delta-(1)-piperideine-2-carboxylate (P2C) to Pip.  Mediates reduction of P2C and biosynthesis of Pip in systemic tissue and contributes to SAR establishment (PubMed:27758894).  Does not possess ornithine cyclodeaminase activity in vitro (PubMed:24237637).
What are the official names of this protein?
Protein SAR DEFICIENT 4, Ornithine cyclodeaminase-like protein, AtOCD.
What is the protein family that this protein belongs to?
Belongs to the ornithine cyclodeaminase/mu-crystallin family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL35_BACC1
Sequence: MPKQKTHRGAAKRFKKTGSGKLKRSHAYTSHLFANKSTKAKRKLRKAGVVSAGDFKRIRQMLDNLK
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: CSXA_CLOS1
Sequence: MFLLYEKEDIYMAINSKDFIPRPGFVNKQGCLPDPVEITCIQVPKVFDQCLIKECLKPTDDCEQLCKQIPNITDPAQVRCVGCCKDLKVKVNSVTKCPVSNGKPGHKKVTINFTVTFDVDVDVEINGVIHTETLNFSVNRTITASNLYCPDAIAKTIIGKECTSAEEIDQQFIKLEVVGECLSTDISKIDCDNDCCSCSCTCEDNGDKKVFLCITLGLFIIIKCEIVVQLMVPAYGYCPVPEECKCSHDPCKEFMERELPTLYPPQEMDNLFDDYDERQDERHIHDRKHIEEEEERGNLVTSSIIASN
What are the official names of this protein?
Exosporium protein A.
What are the subcellular locations of this protein?
Spore wall. Note=Localizes to the exosporium.
Protein: DHFS_ARATH
Sequence: MRTLWNHFSTISYIKISPRMRRISAANLISNRNLSTISSTEDPELRDFVGFLESLKNYEKSGVPKGAGTDSDDGFDLGRMKRLMLRLRNPHYKYKVVHVAGTKGKGSTSAFLSNILRAGGYSVGCYSSPHILSIKERISCNGEPVSASTLNDLFYSVKPILEQSIQEENGSLSHFEILTGIAFSLFEKENVDIAVIEAGLGGARDATNVIESSNLAASVITTIGEEHMAALGGSLESIAEAKSGIIKHGRPVVLGGPFLPHIEGILRSKAASVSSSVILASNIGSSSSIKGIINKNGIGLCQSCDIVIQNEKDDQPIVELSDVNLRMLGHHQLQNAVTATCVSLCLRDQGCGRVTDEAIRIGLENTRLLGRSQFLTPKEAETLLLPGATVLLDGAHTKESARALKEMIKKDFPEKRLVFVVAMASDKDHVSFAKELLSGLKPEAVILTEADIGGGKIRSTESSVLKESWIKAADELGSRSMEASENKTVLGSLKLAYKILSDDTTSSDSGMVIVTGSLHIVSSVLASLQH
What is the function of this protein?
Conversion of folates to polyglutamate derivatives, including tetrahydrofolate (PubMed:11752472, PubMed:12535338).  Required during embryogenesis; from maternal tissues until the globular stage, and from the embryo after the globular stage (PubMed:12535338).
What are the official names of this protein?
Dihydrofolate synthetase, AtDFA, Protein GLOBULAR ARREST 1.
What is the protein family that this protein belongs to?
Belongs to the folylpolyglutamate synthase family.
Protein: COPZ2_MOUSE
Sequence: MQRPEAWPRPHPGEGASAAQAGGAAPPTRATEQREPSLYTIKAVFILDNDGRRLLAKYYDDTFPSVKEQMVFEKNVFNKTSRTESEIAFLGGMTIVYKSSIDIFLYVVGSSSENELMLMSVLACLFDSLSHILRKNVEKRWLLENMDGAFLVLDETVDGGVILESDPQQVIQKVNFRTDDSGLTEQSVAQVLQSAKEQIKWSLLK
What is the function of this protein?
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.  Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.  The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.
What are the official names of this protein?
Coatomer subunit zeta-2, Zeta-2-coat protein, Zeta-2 COP.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes small subunit family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Endoplasmic reticulum-Golgi intermediate compartment membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it. Shows a significant preference for ERGIC and cis-Golgi apparatus compared with trans-Golgi network.
Protein: HOOK2_XENLA
Sequence: MSSKRKVELCDSLLTWMQTFQVSGPCSSYEDLTGGVAIAQVLNRIDPSWFNEAWLVRVKKDTTENWRLKVSNLKRILQSVLEYYQDVLGHPVSDDHIPDVALIGEFSNDTELRKMVQLVLGCAISCDKKEEHIQQIMTLGESVQQAVMESIQELLSKAPSDAVTSESFINYDSQSRKYYFLSEDNDEKNEILQRCHDLEQQVSLLMEEKKNMMGENRTLKEQQEQSGMGTPQLFNKKLLLLQSQIEQLQEENYRLESSRDDYRQRCQELDRDVQELQQRNQDLTGLAHESQALRDEMDVLRHSSDRVGKLESLVDSYKKKLEDLGDLRRQVKLLEERNTMYMQRTFQLEEDLHKANASRGQVESLSRQVQELHKKHSTESLRAEKWQFEFQTLKEKFEALQKERERLIAERDSLRETNDELRCSHLQQTCLGQADLLLSGSSPPLENLAAEIVPAELRETVIRLQQENKMLCAQEASYHERLCDLQNFLEESNRSKNRLESESRLQQQQIKGLKAQVEELQKQLREQGNRAEDSSQLKRKLEEHLEMLHDAHSELQKKREYIETLEPKADLNMSRKVDELQQILHQKEEDMRAMEERYKRYVDKARTVIKSLDPKQQNYIPPEIQALKNQLQEKDTRIRHLETDYEKTKVQRDQEEKLIISAWYNMGMALHQKSTDEKTQPPNGAQSFLAQQRLATNARRGQISRSHTLLPRYTDKRQSLS
What is the function of this protein?
May function to promote vesicle trafficking and/or fusion.  May contribute to the establishment and maintenance of centrosome function (By similarity).
What are the official names of this protein?
Protein Hook homolog 2.
What is the protein family that this protein belongs to?
Belongs to the hook family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Cytoplasm, cytoskeleton.
Protein: RL28_BRUC2
Sequence: MSRACELTGKSVQYGNNVSHANNRTRRRFLPNLCNVTLISETLGQSYRLRISANALRSVEHRGGLDAFLVKSDDKELSQRARLLKRQIAKKQAEAAA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: MCA1_MAGO7
Sequence: MSGYPGQGYQGQGYGQGYGQGYPPQGGYYPPQPGYGGYPPQPPPPQHYQYGPPQGGYQYPPQDGSRAGPSDQAHQPPQGMQQFGHGAPSDYAFQYSQCTGKRKALLIGINYFGQEGELRGCINDVRNLSNFLMEFYQYRREDMVLLTDDAQDPMSQPTRDNIVRAMHWLVEGAQPNDSLFFHYSGHGGQTEDLDGDEDDGYDEVIYPVDFRANGHIVDDDMHLWMVQPLQAGVRLTAIFDSCHSGTALDLPYVYSTSGVLKEPNLAKEAGVGLLGAVQSYARGDLGGVATSLFGFAKKAFSDKQARDRTMRTKTSPADVISWSGSKDDQTSADATIASQATGAMSYAFVSALRANRNQTYNQLLNSIRDILEGQYSQKPQLSCSHPLDTENVWFVM
What is the function of this protein?
Involved in cell death (apoptosis).
What are the official names of this protein?
Metacaspase-1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14B family.
Protein: RSMG_DEIDV
Sequence: MNPEATELLLAGAQELGLDVAPVLDQFAALLVLLQEGNARFNLTALKTERDIVLKHFVDSLTCLGGGHLDGNHQVVDLGTGAGFPTLPLALMRAELQFTPVDSTRKKVEFVRATAEALGLQNVRPVAGRAETLTRQPEHRDRYDRVVVRAVAALPILAELALPFLRPGGLLVAQKGPISPEELRAGQRAAGELGGRVTEVEAFTLPVLGDARTLVVVEKLRDTPDRYPRREGVPNQQPLFWSAK
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GB_HHV1F
Sequence: MRQGAARGCRWFVVWALLGLTLGVLVASAAPSSPGTPGVAAATQAANGGPATPAPPAPGPAPTGDTKPKKNKKPKNPPPPRPAGDNATVAAGHATLREHLRDIKAENTDANFYVCPPPTGATVVQFEQPRRCPTRPEGQNYTEGIAVVFKENIAPYKFKATMYYKDVTVSQVWFGHRYSQFMGIFEDRAPVPFEEVIDKINAKGVCRSTAKYVRNNLETTAFHRDDHETDMELKPANAATRTSRGWHTTDLKYNPSRVEAFHRYGTTVNCIVEEVDARSVYPYDEFVLATGDFVYMSPFYGYREGSHTEHTSYAADRFKQVDGFYARDLTTKARATAPTTRNLLTTPKFTVAWDWVPKRPSVCTMTKWQEVDEMLRSEYGGSFRFSSDAISTTFTTNLTEYPLSRVDLGDCIGKDARDAMDRIFARRYNATHIKVGQPQYYLANGGFLIAYQPLLSNTLAELYVREHLREQSRKPPNPTPPPPGASANASVERIKTTSSIEFARLQFTYNHIQRHVNDMLGRVAIAWCELQNHELTLWNEARKLNPNAIASATVGRRVSARMLGDVMAVSTCVPVAADNVIVQNSMRISSRPGACYSRPLVSFRYEDQGPLVEGQLGENNELRLTRDAIEPCTVGHRRYFTFGGGYVYFEEYAYSHQLSRADITTVSTFIDLNITMLEDHEFVPLEVYTRHEIKDSGLLDYTEVQRRNQLHDLRFADIDTVIHADANAAMFAGLGAFFEGMGDLGRAVGKVVMGIVGGVVSAVSGVSSFMSNPFGALAVGLLVLAGLAAAFFAFRYVMRLQSNPMKALYPLTTKELKNPTNPDASGEGEEGGDFDEAKLAEAREMIRYMALVSAMERTEHKAKKKGTSALLSAKVTDMVMRKRRNTNYTQVPNKDGDADEDDL
What is the function of this protein?
Envelope glycoprotein that forms spikes at the surface of virion envelope.  Essential for the initial attachment to heparan sulfate moieties of the host cell surface proteoglycans.  Involved in fusion of viral and cellular membranes leading to virus entry into the host cell.  Following initial binding to its host receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.  May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress (By similarity).  Also plays a role, together with gK, in virus-induced cell-to-cell fusion (syncytia formation).
What are the official names of this protein?
Envelope glycoprotein B, gB.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein B family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN).
Protein: SLMA_SHEDO
Sequence: MATSPKINRREHILQCLAQMLETSPGQRITTAKLAAEVGVSEAALYRHFPSKARMFEGLIEFIEDAILSRLNLIMDEEKDTMMRCQLVLQLLLVFSERNPGISRVLNGDALLGENERLRSRISVLFAKIETQLKQILREKTLREGQGFNLDEAILANLLLAVAEGRIAQFVRSEFKQKPTLHFDEQWTFIQQQLLRS
What is the function of this protein?
Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid.  Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers.  SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
What are the official names of this protein?
Nucleoid occlusion factor SlmA.
What is the protein family that this protein belongs to?
Belongs to the nucleoid occlusion factor SlmA family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: GLL12_CHICK
Sequence: MRNLCFVFIFISLLAHGSTHGPDSCNHDRGLCRVGNCNPGEYLAKYCFEPVILCCKPLSPTPTKT
What is the function of this protein?
Has bactericidal activity.
What are the official names of this protein?
Gallinacin-12, Gal-12, Beta-defensin 12, Gallinacin-10, Gal-10.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic granule.
Protein: Y3453_PECCP
Sequence: MSAITRHGDALVIRLYIQPKASRDQIVGLHGDELKVAITAPPVDGQANAHLTKFLAKQFRVAKSLVVIEKGELGRHKQIRITHPQHIPADVADFIE
What are the official names of this protein?
UPF0235 protein PC1_3453.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: Y1825_MYCTU
Sequence: MSENRPEPVAAETSAATTARHSQADAGAHDAVRRGRHELPADHPRSKVGPLRRTRLTEILRGGRSRLVFGTLAILLCLVLGVAIVTQVRQTDSGDSLETARPADLLVLLDSLRQREATLNAEVIDLQNTLNALQASGNTDQAALESAQARLAALSILVGAVGATGPGVMITIDDPGPGVAPEVMIDVINELRAAGAEAIQINDAHRSVRVGVDTWVVGVPGSLTVDTKVLSPPYSILAIGDPPTLAAAMNIPGGAQDGVKRVGGRMVVQQADRVDVTALRQPKQHQYAQPVK
What are the official names of this protein?
UPF0749 protein Rv1825.
What is the protein family that this protein belongs to?
Belongs to the UPF0749 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PYRG_CORK4
Sequence: MSQPRAEHVTKFVFVTGGVASSLGKGLTASSLGQLLTARGLKVTMQKLDPYLNVDPGTMNPFQHGEVFVTDDGAETDLDLGHYERFLNRNLSGNANVTTGQVYSEVIAKERRGEYLGDTVQVIPHITDEIKHRILTMDRPDENGVRPDIVITEIGGTVGDIESQPFLEAARQTRHDVGRENIFFIHVSLVPYLAPSGELKTKPTQHSVAALRSIGIVPDALVLRCDREVPEPLKAKIALMCDVDQEGVISCADADSIYEIPKVLHREHLDAFLIRRLDLPFRDVDWEEWDSLLRKVHEPEHELTVALVGKYIDLPDAYLSVTEAIRAGGFANNARARVKWVPSDLCQTEEGAEKELGNVDAIVVPGGFGIRGIEGKIGAVRYARTHRVPFLGLCLGLQCMVIEAARAAGITDASSTEFDPQTTEPVVSTMAEQMAAVSGEADLGGTMRLGAYPAVLDKGSVVAEAYQTLEVSERHRHRYEINNAYRQRITDGVGLKFSGTSPDGKLVEFIEYPDHPYMVATQAHPEYKSRPTKAHPLFTALVKAGLKHKNDEEK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.