PharMolix/UniProtQA huggingface dataset:
Protein: PDXJ_RHOBA
Sequence: MPHFIDLGVNVDHVATLRQARRGQEPDPITAASLAEQGGADGITFHLREDRRHISDRDVELFVQTVQVRTNFELACAADVLAICCRVQPDWALLVPESREEVTTEGGLDVAGDSGRIADAIQMLKDAGIATSLFLDPEPNQIEAAAKLQVDAVELHTGPYALARGAAVQHELRRLADTGKMIRDAGMRLHAGHGLNYVNVRPVAAIDGMAELNIGHSIVSRSVMVGMREAVAEMRRLLDSVTIAAQ
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VIT_ONCMY
Sequence: MRAVVLALTLALVASQSVNFAPDFAASKTYVYKYEALLLGGLPEEGLARAGVKVISKVLISAVAENTYLLKLVNPEIFEYSGVWPKDPFVPAAKLTSALAAQFSIPIKFEYAKGVVGKVLAPTAVSETVLNVHRGILNILQLNIKKTQNVYELQEAGAQGVCKTHYVIREDAKAERIHLTKSKDLNNCQQRIMKDFGLAYTEKCVECRQRGEALMGAATYNYLMKPADNGALILEATVTELHQFTPFNEMSGAAQMEAKQMLTFVEIKKDPIIVPDNNYVHRGSIRYEFATEILQMPIQLLKISNARAQAVKILNHLVTYNTAPVHEDAPLKFLQFIQLLRMASSETINAIWAEFKAKPAYRHWILDAVPSIGSSVAVRFIKEKFLAGDITIFEAAQALVAAVHMVAADLETVKLVESLAFNHKIQTHPVLRELTMLGYGTMVSKYCVEHPNCPAELVKPIHELAVQAVANSKFEELSMVLKALGNAGHPASIKPITKLLPVFGTAAAALPLRVQADAVLALRNIAKREPRMVQEVAVQLFMDKALHPELRMLACIVLFETKPPMGLVITLASILKTEKNMQVASFTYSHMMSLTRSTAPDFASVAAACNVAVKMLSNKFRRLSCHFSQAIHLDAYSNPLRIGAAASAFYINDAATLFPRTVVAKARTYFAGAAADVLEVGVRTEGIQEALLKLPPAPENADRITKMRRVIKALSDWRSLATSKPLASIYVKFFGQEIAFANIDKSIIDQALQLANSPSAHALGRNALKALLAGATFQYVKPLLAAEVRRIFPTAVGLPMELSYYTAAVAKAYVNVRATLTPALPETFHAAQLLKTNIELHAEVRPSIVMHTFAVMGVNTAFIQAAIMARAKVRTIVPAKFAAQLDIANGNFKFEAFPVSPPEHIAAAHIETFAVARNVEDVPAERITPLIPAQGVARSTQQSRDKLTSMIADSAASFAGSLSRSSEILYSDLPSNFKPIIKAIVVHLEETICVERLGVKACFEFTSESAAFIRNTLFYNMIGKHSVLISVKPSASEPAIERLEFEVQVGPKAAEKIIKVITMNEEEEAPEGKTVLLKLKKILLPDLKNGTRASSSSSSSSSSSSRSSSSRSRSRKSESSSSSSSSSSRISKRDGPDQPYNPNDRKFKKNHKDSQSTSNVISRSKSSASSFHAIYKQDKFLGNKLAPMVIILFRLVRADHKIEGYQVTAYLNKATSRLQIIMAALDENDNWKLCADGVLLSKHKVTAKIAWGAECKDYNTFITAETGLVGPSPAVRLRLSWDKLPKVPKAVWRYVRIVSEFIPGYIPYYLADLVPMQKDKNNEKQIQFTVVATSERTLDVILKTPKMTLYKLGVNLPCSLPFESMTDLSPFDDNIVNKIHYLFSEVNAVKCSMVRDTLTTFNNKKYKINMPLSCYQVLAQDCTTELKFMVLLKKDHASEQNHINVKISDIDVDLYTEDHGVIVKVNEMEISNDNLPYKDPSGSIKIDRKGKGVSLYAPSHGLQEVYFDKYSWKIKVVDWMKGQTCGLCGKADGENRQEYRTPSGRLTKSSVSFAHSWVLPSDSCRDASECLMKLESVKLEKQVIVDDRESKCYSVEPVLRCLPGCLPVRTTPITIGFHCLPVDSNLNRSEGLSSIYEKSVDLMEKAEAHVACRCSEQCM
What is the function of this protein?
Precursor of the major egg-yolk proteins that are sources of nutrients during early development of oviparous organisms.
What are the official names of this protein?
Vitellogenin, VTG.
Protein: RL34_YERPG
Sequence: MKRTFQPSVLKRNRSHGFRARMATKNGRQVLARRRAKSRSRLTVSK
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: TGB3_PMV
Sequence: MFSGKEITLFALSTLIALIVLNYMSATPNPVCLIELTGHSAVLRGNNCESLTSGVIEALSAHLHGLRN
What is the function of this protein?
Plays a role in viral cell-to-cell propagation, by facilitating genome transport to neighboring plant cells through plasmosdesmata.  May induce the formation of granular vesicles derived from the Endoplasmic reticulum, which align on actin filaments (By similarity).
What are the official names of this protein?
Movement protein TGBp3, 7 kDa protein, Triple gene block 3 protein, TGBp3.
What is the protein family that this protein belongs to?
Belongs to the Tymovirales TGBp3 protein family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane.
Protein: DDC_PIG
Sequence: MNASDFRRRGKEMVDYMADYLEGIEGRQVYPDVQPGYLRPLIPATAPQEPDTFEDILQDVEKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMDWLGKMLQLPEAFLAGEAGEGGGVIQGSASEATLVALLAARTKVVRRLQAASPGLTQGAVLEKLVAYASDQAHSSVERAGLIGGVKLKAIPSDGKFAMRASALQEALERDKAAGLIPFFVVATLGTTSCCSFDNLLEVGPICHEEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKRRTDLTGAFKLDPVYLKHSHQGSGLITDYRHWQLPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFEAFVLQDPRFEVCAEVTLGLVCFRLKGSDGLNEALLERINSARKIHLVPCRLRGQFVLRFAICSRKVESGHVRLAWEHIRGLAAELLAAEEGKAEIKS
What is the function of this protein?
Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine and L-5-hydroxytryptophan to serotonin.
What are the official names of this protein?
Aromatic-L-amino-acid decarboxylase, AADC, DOPA decarboxylase, DDC.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
Protein: SYY_DINSH
Sequence: MTYQPKSDFMRVMMERGFLADCTDYQGLDEAMSKGVVPTYIGYDATAASLHVGHLLNIMMLRWLQKTGHKPITLMGGGTTKVGDPSFRSDERPLLGAEQIDANIAGMKQVFSSYLTYGDGPTDALMLNNAEWLDGLNYLEFLRDVGRHFSVNRMLSFESVKSRLDREQSLSFLEFNYMILQAYDFMELNRRYGCRLQMGGSDQWGNIVNGIDLTRRILDQEVYGLTSPLLTTSDGRKMGKSQGGAIWLNGDMLSPYEFWQFWRNTTDADVGRFLKLYTELPLEECDRLGALAGSEINDAKIILANAVTALLHGPEAAQAAEATAREVFEKGGAGEDLPTLTLTTDEIGDGISVVQLITRSGLAKSGKEAKRLIAENGAKLDDAPLTDAGLMIDADRLAAPIKLSAGRKRHALIKRAD
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KFA_SALSA
Sequence: MSRWKDMNKDELERQFSPSQWSHRMSADDVIKSHVTALKEGTERARGLAQTLLNVPYGEGEGEKLDVYVPTTTSLDVPLVIYLHGGYWQFLSKEESGFMAVPLVHKGVVVVAVGYDIAPKGNMDVMVSQVRRSVVSVIQQYSHISGLYLCGHSAGAHLAAMILSTDWSQYSVTPQIKGAFLVSGIYDLLPILSTYVNEPLKMTEEVALRNSPSQLVPQLKLSSSNCDIVVAVAQNDSPEFRKQSEDYYKALESTEGLKVTLEDVPNTDHFNIIEQLVDGDYHLTQLLLKMMGKS
What is the function of this protein?
Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.  Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H).  Required for elimination of toxic metabolites.
What are the official names of this protein?
Kynurenine formamidase, KFA, KFase, Arylformamidase, N-formylkynurenine formamidase, FKF.
What is the protein family that this protein belongs to?
Belongs to the kynurenine formamidase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus.
Protein: GRK5_RAT
Sequence: MELENIVANTVLLKAREGGGGKRKGKSKKWKEILKFPHINQCEDLRRTIDRDYYSLCDKQPIGRLLFRQFCETRPGLECYIQFLDLVAEYEITPDENLGAKGKEIMTKYLSPKSPVFIAQVGQDLVSQTEKKLLQSPCKELFSACAQSVHDYLKGDPFHEYLDSMYFDRFLQWKWLERQPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEKVNSQFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAAEILCGLEDLHRENTVYRDLKPENILLDDYGHIRISDLGLAVKIPEGDLIRGRVGTVGYMAPEVLNNQRYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETEEVYSPKFSEEAKSICNMLLTKDSKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGMLDPPFVPDPRAVYCKDVLDIEQFSTVKGVNLDHTDDDFYSKFSTGSVPIPWQNEMIETECFKELNVFGPNGTLSPDLNRSQPPEPPKKGLFHRLFRRQHQNNSKSSPTPKTSCNHRINSNHINSNSTGSS
What is the function of this protein?
Serine/threonine kinase that phosphorylates preferentially the activated forms of a variety of G-protein-coupled receptors (GPCRs).  Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their down-regulation.  Phosphorylates a variety of GPCRs, including adrenergic receptors, muscarinic acetylcholine receptors (more specifically Gi-coupled M2/M4 subtypes), dopamine receptors and opioid receptors.  In addition to GPCRs, also phosphorylates various substrates: Hsc70-interacting protein/ST13, TP53/p53, HDAC5, and arrestin-1/ARRB1.  Phosphorylation of ARRB1 by GRK5 inhibits G-protein independent MAPK1/MAPK3 signaling downstream of 5HT4-receptors.  Phosphorylation of HDAC5, a repressor of myocyte enhancer factor 2 (MEF2) leading to nuclear export of HDAC5 and allowing MEF2-mediated transcription.  Phosphorylation of TP53/p53, a crucial tumor suppressor, inhibits TP53/p53-mediated apoptosis.  Phosphorylation of ST13 regulates internalization of the chemokine receptor (By similarity).  Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor, LRP6 during Wnt signaling (in vitro) (By similarity).
What are the official names of this protein?
G protein-coupled receptor kinase 5, G protein-coupled receptor kinase GRK5.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein. Note=Predominantly localized at the plasma membrane, targeted to the cell surface through the interaction with phospholipids. Nucleus localization is regulated in a GPCR and Ca(2+)/calmodulin-dependent fashion (By similarity).
Protein: NDUA5_RAT
Sequence: MAGLVKKTTGLVGLAVCDTPHERLTILYTKILDLLKHFPKHAAYRKYTEQITSEKLELVKLEPDVKKLENLLQGGEVEEVILQAEKELSLARKMLQWKPWEPLVEEPPANQWKWPI
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5, Complex I subunit B13, Complex I-13kD-B, CI-13kD-B, NADH-ubiquinone oxidoreductase 13 kDa-B subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFA5 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: MDH_ECOL6
Sequence: MKVAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAVDLSHIPTAVKIKGFSGEDATPALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKNLVQQVAKTCPKACIGIITNPVNTTVAIAAEVLKKAGVYDKNKLFGVTTLDIIRSNTFVAELKGKQPGEVEVPVIGGHSGVTILPLLSQVPGVSFTEQEVADLTKRIQNAGTEVVEAKAGGGSATLSMGQAAARFGLSLVRALQGEQGVVECAYVEGDGQYARFFSQPLLLGKNGVEERKSIGTLSAFEQNALEGMLDTLKKDIALGEEFVNK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: LYSB_DROME
Sequence: MKAFIVLVALALAAPALGRTMDRCSLAREMSNLGVPRDQLARWACIAEHESSYRTGVVGPENYNGSNDYGIFQINDYYWCAPPSGRFSYNECGLSCNALLTDDITHSVRCAQKVLSQQGWSAWSTWHYCSGWLPSIDDCF
What is the function of this protein?
Unlikely to play an active role in the humoral immune defense.  May have a function in the digestion of bacteria in the food.
What are the official names of this protein?
Lysozyme B, 1,4-beta-N-acetylmuramidase B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
Protein: GPSB_STRP2
Sequence: MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAALVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQILDNSDF
What is the function of this protein?
Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome.  Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression.  Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed.  Also contributes to the recruitment of PBP1 to the division complex.  Not essential for septum formation.
What are the official names of this protein?
Cell cycle protein GpsB, Guiding PBP1-shuttling protein.
What is the protein family that this protein belongs to?
Belongs to the GpsB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Shuttles between the lateral wall and the division site in a cell cycle-dependent manner.
Protein: Y1870_ARCFU
Sequence: MSSTMSFDNLAKVLAVLVAEQGSYTYVDKLGYVPSKDLAVFYLKEALRDLHSIQQKEKFENEKARELVGKIDYERVEKELEDIAKTDERKELREKTSLIAAKALALSAKLGGGSGE
What are the official names of this protein?
Uncharacterized protein AF_1870.
Protein: ATPE_PERMH
Sequence: MYPLEVVTPEGIVFKGEVEQTVINTADGEIGILENHMLLLTNVVPGKLRIEIPEEEPKEYAVTHGVIDVRGDKVIVLVEEAFGISEIDVEREKRLLEEAKAKLEERETLSLEEIENYERMKERAEILLELAGVKVR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: COAX_BURM9
Sequence: MCLLIDAGNSRIKWALADTARHFVTSGAFEHASDAPDWSTLPAPRGAWISNVAGDAAAARIDALIEARWPALPRTVVRASAAQCGVTNGYAEPARLGSDRWAGLIGAHAAFADEHLLIATFGTATTLEALRADGHFAGGLIAPGWALMMRSLGMHTAQLPTVSIDAATNLLDELAENDAHAPFAIDTPHALSAGCLQAQAGLIERAWRDLEKAWQAPVRLVLSGGAADAIVRALTVPHTRHDTLVLTGLALIAHSA
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADK_CLOBK
Sequence: MKNIGININTDKDISRNILDKIFQYIHEECSEAKIKVFYDSKGLDNEESRALDAVMVLGGDGTILGTARALAKYDVPIFGINRGHLGFLAEIELEDCKKAIKNLFKGQYKIEDRIMLKCDLKGIDKKDDFLALNDIVLTKGNLSRIVKYSIYVDDVWYTTFVADGVIVATPTGSTAYSLSAGGPIVYPDLDVLEIAPICPHSLGIRPILLNGNSKINIRVLKKYEDPVLTIDGQRYKKVTVNEVTISKSEYKCRLIKFKDKDYFKILRTKISYRSRECEGE
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRI_STRPU
Sequence: MVEDQRRQLMEEEDEERRLILEEQRRRMMRADRDEEEEEEEEEEEEEREEDDGRRSEDEMREDEPPGRRETSHAHIDLNMMRANAHLKEMMDKNRRFVSTRLEEPITQSPPLTNGSNHDNDHDPYLSHRAAHGGSPDLPHSYMKAAHPLIKKEDGIAKMEMDIGLKDEMKMGAGLEDRDGDKPQTEWSFEEQFKQLYELSTDSKRKEFLDDLFSYMQKRGTPVNRIPIMAKQVLDLYELYNLVVAKGGLVEVINKKQWREITKGLNLPASITSAAFTLRTQYMKYLYPYECEKKGLSSPSELQSAIDGNRREGRRPSYHSPHMHPRGPSLAYHHGLDLHTPSGSPPPTMIPHPSRIPTLPPRLSPSTSPIEDDHPVPLGFPRQGTLSHAAMLAELAERGSIPPPSKRSLLAEEHHHRLLQLQQQHLVMPTAHLKVSSARAHPENGMPLFEMRGDNSLVMSIELNSVLYQGVLYPRGGTRSSLDRDTSTPV
What is the function of this protein?
Transcription factor involved in skeletogenesis and oral ectoderm patterning.
What are the official names of this protein?
Protein dead ringer homolog, Deadringer-like protein, Spdeadringer, Spdri.
What are the subcellular locations of this protein?
Nucleus.
Protein: TNAA_SHIFL
Sequence: MENFKHLPEPFRIRVIEPVKRTTRAYREEAIIKSGMNPFLLDSEDVFIDLLTDSGTGAVTQSMQAAMMRGDEAYSGSRSYYALAESVKNIFGYQYTIPTHQGRGAEQIYIPVLIKKREQEKGLDRSKMVAFSNYFFDTTQGHSQINGCTVRNVYIKEAFDTGVRYDFKGNFDLEGLERGIEEVGPNNVPYIVATITSNSAGGQPVSLANLKAMYSIAKKYDIPVVMDSARFAENAYFIKQREAEYKDWTIEQITRETYKYADMLAMSAKKDAMVPMGGLLCMKDDSFFDVYTECRTLCVVQEGFPTYGGLEGGAMERLAVGLYDGMNLDWLAYRIAQVQYLVDGLEEIGVVCQQAGGHAAFVDAGKLLPHIPADQFPAQALACELYKVAGIRAVEIGSFLLGRDPKTGKQLPCPAELLRLTIPRATYTQTHMDFIIEAFKHVKENAANIKGLTFTYEPKVLRHFTAKLKEV
What are the official names of this protein?
Tryptophanase, L-tryptophan indole-lyase, TNase.
What is the protein family that this protein belongs to?
Belongs to the beta-eliminating lyase family.
Protein: CCMA_PSEPF
Sequence: MTSPVLQTVALACERDLRLLFDNLELRLASGDMVQISGPNGSGKTSLLRLLAGLMQPTDGQVLLNGKPLGEQRSELARNLLWIGHAAGIKDLLTPEENLTWLCALHQPAERDAIWQALAAVGLRGFEDVPCHSLSAGQQRRVALARLYLDSPPLWILDEPFTALDKQGVAQLEEHLAGHCERGGLVVLTTHHTLSRMPAGYRDIDLGNWAV
What is the function of this protein?
Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MNME_POLAQ
Sequence: MMTRKVPIIAVATAPGKAGVGVVRISGQGLGELVETLFHRSLAPRQATLLTFCDADNQPIDQLLAIYFVGPASFTGEDVLELQCHGGPQLLELVMKRCLELGKALGLVIAEPGEFTLRAYLNNKVDLAQAEAIADLIDAQSEAAVRGAARSLQGSFSEDINGLIEEITQLRILVESTLDFPEEEIEFLENAQARERLAAVKKKLEALQAGAKQGKILRDGIQLVLAGAPNVGKSSLLNRLAGEEVAIVTPIAGTTRDRVKESIQIEGVPMHIIDTAGLRKTVDEVEAKGIERTWEAIRLADLVIFLGAPNAEPGHESLREEILGALPAKCPILDVINKSDLIEGGLAVSSSNEASPLLISAKTGAGIDALKQKILHVVGWNGAQEGAIVSRRRHLDCLERAAEHIAKSEQFAANGNNSLELFAEELFLAQNHLGQITGKLLPDDLLGKIFSQFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_DELAS
Sequence: MIQTESRLEVADNTGAKSVQCIKVLGGSHRRYASVGDIIKVTIKEAAPRGRVKKGEVYSAVVVRTAKGIRRADGSLVKFDGNAAVLLNAKLEPIGTRIFGPVTRELRNEKFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: CLA4_YEAST
Sequence: MSLSAAANKISDNDFQNIGPAPRPPSSNSQGRTCYNQTQPITKLMSQLDLTSASHLGTSTSKKKSGWVSYKDDGILSFIWQKRYLMLHDSYVALYKNDKQNDDAILKIPLTSIISVSRTQLKQYCFELVRCSDRNSVSSGSSSSLNVSSDSNSKKSIYIATKTESDLHSWLDAIFAKCPLLSGVSSPTNFTHKVHVGFDPETGSFVGMPTNWEKLLKHSRITGEDWNNNSAAVIQVLQFYQEYNGAGNPTNTLDKPQSGETSSSQKSLPNSYNDNKLRNNSVNSKSSSGVSSSMVSQRKTSQPPNTKSPVSLGSGSLPPINTKLPTSQSNIPRHLQNVPNQQYPKMRNGHSPTNGQFPRGPMHPNNSQRSLQQQQQQQQQQKQQHQQYPYHHQGPSPSPSPSPSPLNPYRPHHNMINPYSKQPQSPLSSQSTQNQAIPRYAQNSSPTAAHFQPQRTAPKPPISAPRAPYPSNQNATSNTHVQPVAPKNDQSTPQTMRQAPKRPDADVAQPGGVAKPKKPARPTMSTAEIMSKLKKVTVNADPSQCFKVIEKAGQGASGSVYLAERTHIPTESNMIELINNDIDEPHVGDKVAIKQMVLSKQPRKELIVNEILVMKDSRHKNIVNFLEAYLRTDDDLWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRARVKITDFGFCARLTDKRSKRATMVGTPYWMAPEVVKQREYDEKIDVWSLGIMTIEMLEGEPPYLNEDPLKALYLIATNGTPKLKHPESLSLEIKRFLSVCLCVDVRYRASTEELLHHGFFNMACDPKDLTSLLEWKE
What is the function of this protein?
Involved in budding and cytokinesis.
What are the official names of this protein?
Serine/threonine-protein kinase CLA4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
Protein: IHFB_BUCAP
Sequence: MTKSELFERIAERKAHISNKIIECAVKEMLEYISISLSKGKRIEIRGFGTFSLHYRSSRIGRNPKTGKKIKLNERYIPYFKPGKQLRDRANYK
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: SYT_METMA
Sequence: MQLLLIHSDYIEYETKKQTPVAEKIEESLKSGRLEEALTAFTAVESVDEANPEEAIKKAVSEIEKVAAQVKTNRIMLYPYAHLSSDLSSPKVAVQVLKGMEAALSSRYEVKRAPFGWYKAFTVSCKGHPLSELSRSIRPEGAAKAEVKTETCEKEEVVSEALKAEGTARSYWRILTPDGELHEVEGFDLTPYPKLQQFVNYEISKSRAVERAPPHVELMRRLELADYEPGSDSGNMRYYPKGRLVKSLLENYVLDVATEFGAMEVETPLMYDMNHPTLKKYLDRFPARQYSIESDKRHMFLRFAACFGQFLMNHDMTISYKNLPLRMIEMTRYSFRKEQRGELVGLRRLRAFTMPDMHTLCEDMDQAVNQFKEQYDLCISVLENVGIHINDYEVAIRFTRDFYEANKDLVVNMAKTVNKPVLVEMWDTRFFYFVLKFEFNFVDALAKASALSTVQIDVENAERYDISYVNADGKLERPTVLHCSPSGAIERCIYALLEKAAMETEEGKVPMLPVWLSPTQVRIVPISEKHIAFAEEVAKKLDFRVDVDDRDLSIGKKVREAGREWVPYVVVIGDKEMEESTINVTIREESGQDKPKKVQMTPEELNARIKEETSGKPYRKLPLAKYLSARPKFL
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) (Probable).  Edits incorrectly charged L-seryl-tRNA(Thr) probably via its editing domain (tested with total bovine tRNA) (PubMed:15079065).  Activates L-serine, but does not detectably transfer it to tRNA (tested with total bovine tRNA) (PubMed:15079065).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROL_SALHS
Sequence: MMQPLYLVGPRGCGKTTIGMALAQATGFRFADTDRWLQSHVQMSVADIVEKEGWGGFRARETAALEAVSAPSTVVATGGGIILTEYNRRYMHRVGVVIYLCAPVSTLVNRLEAEPEADLRPTLTGKPLSEEVREVLEQRDALYRETAHYIIDATKTPAQVVSEIIAALPPSTQRLQGDVYT
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase 2, SK 2.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family. AroL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.