PharMolix/UniProtQA huggingface dataset:
Protein: JUPIT_DROER
Sequence: MISNFDCTDNQASSKVLRPPGGGSSDIFGSEMPQTPRNVKNRMASNIFAAEKDNGVKNNVRQGAHRFYFIGDAPRRGQKTVDSHNRLFGEPTRPITPGKNHMKSSIPFGQNTEAVASAQKLLTTNGHYNGKSGSVSSASSSVSSSTENLKMNSGSRSVFRNMSTGPAVKETSLPESLCPPSPVRIEPPTPPADALSIDNSCRDSEIGDVPADNSTYTKSDQVNEACQTRRDSGNNPEQPHSLDKMAGVANIKEPLGLCPNDVKEGAQACSKLDSRNPITGLGLNGDGVGGLKPKKLKIREGNPVTGEGYKAGGNDYNQRQESSNAGTPVINKNRIPPGGYSSGLW
What is the function of this protein?
Binds to all microtubule populations.
What are the official names of this protein?
Microtubule-associated protein Jupiter.
What is the protein family that this protein belongs to?
Belongs to the MAP Jupiter family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle.
Protein: FLGA1_HALVD
Sequence: MFENINEDRGQVGIGTLIVFIAMVLVAAIAAGVLVNTAGFLQATAEDAGQQSVNKVTNRVDVVNAHGLVNKTGEERTVDQIFLTVRLAAGSGSVSLEDTTVKYLSETTARTLTYNDTVTGSDTADPANLTTGNNFTAGVLEDGDDSFEVLNEQSDRAEMVINTSTVEGDNTNGTATGQTVKLDITSRNGGTAQVILTMPQQLAGKDNNDPIAL
What is the function of this protein?
Major flagellin required for motility.  Not involved in PibD-dependent surface adhesion.  Much more abundant in cells compared to FlgA2.
What are the official names of this protein?
Flagellin A1.
What is the protein family that this protein belongs to?
Belongs to the archaeal flagellin family.
What are the subcellular locations of this protein?
Archaeal flagellum.
Protein: COA7_CAEEL
Sequence: MSGKISEEAMQEQAERAEYVKNIGIEYRFGCYEEKRPESCQLLGEYMEALQQNFQAAVAIFKKNCDENSYPKSCFKYGMYMLAGKVGDDASLSKMIRPMKIACDANIPQGCRYLSLVHWNGEKDRKADSEKAERYMRRACELEDGEACWLLSTWYMGNKEKFKTNAAGEAKELDRAELGSLSRDMDKSLQFAIRACEMDIPQSCANVSRMFKLGDGVPKDLDQAKKYADRAKEIMETLRSNDTNAGFTG
What are the official names of this protein?
Cytochrome c oxidase assembly factor 7 homolog, Beta-lactamase hcp-like protein coa-7, Sel1 repeat-containing protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the hcp beta-lactamase family.
Protein: DT3E_CERSP
Sequence: MKNPVGIISMQFIRPFTSESLHFLKKSRALGFDFIELLVPEPEDGLDAAEVRRICEGEGLGLVLAARVNLQRSIASEEAAARAGGRDYLKYCIEAAEALGATIVGGPLYGEPLVFAGRPPFPWTAEQIATRAARTVEGLAEVAPLAASAGKVFGLEPLNRFETDIVNTTAQAIEVVDAVGSPGLGVMLDTFHMNMEERSIPDAIRATGARLVHFQANENHRGFPGTGTMDWTAIARALGQAGYAGPVSLEPFRRDDERVALPIAHWRAPHEDEDEKLRAGLGLIRSAITLAEVTH
What is the function of this protein?
Catalyzes the epimerization of various ketoses at the C(3) position.  It is able to interconvert D-tagatose and D-fructose to D-sorbose and D-psicose, respectively.  The enzyme is also able to accept other ketopentoses such as D-ribulose and D-xylulose with lower efficiency.
What are the official names of this protein?
D-tagatose 3-epimerase, DTE, D-ribulose 3-epimerase, Ketose 3-epimerase.
What is the protein family that this protein belongs to?
Belongs to the hyi family.
Protein: DTD_EDWI9
Sequence: MIALIQRVTHASVMVDNQLIGEIGAGLLVLLGVERGDDEQKAKRLCDKVLGYRVFSDEEGKMNLNVRQSGGSVLVVSQFTLAADTQKGMRPGFSRGAAPDEAERLYTHFSDACRASGITTATGCFAADMQVSLLNDGPVTFWLQV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECX_THEMA
Sequence: MDYYQWRKKNRGKKRNLQAKKPLNYALRLLKYRVRFEDELRERLKKQGFADEEVESTITTLKKQGYLDDEKAAYLFALDEMRLKLFGPRVVKMKLKSLGVDEEIIERAIEKALEEIDFHEELKRLKGRFKDRWELRDYLYRRGFDSSLIEEILNKIDGGEE
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YAFT_ECOLI
Sequence: MNSKKLCCICVLFSLLAGCASESSIDEKKKKAQVTQSNINKNTPQQLTDKDLFGNETTLAVSEEDIQAALDGDEFRVPLNSPVILVQSGNRAPETIMQEEMRKYYTVSTFSGIPDRQKPLTCNKNKDKNENEDVASAENMNWMQALRFVAAKGHQKAIIVYQDMLQTGKYDSALKSTVWSDYKNDKLTDAISLRYLVRFTLVDVATGEWATWSPVNYEYKVLPPLPDKNEASTTDMTEQQIMQLKQKTYKAMVKDLVNRYQ
What are the official names of this protein?
Uncharacterized lipoprotein YafT.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: SAG1_YEAST
Sequence: MFTFLKIILWLFSLALASAININDITFSNLEITPLTANKQPDQGWTATFDFSIADASSIREGDEFTLSMPHVYRIKLLNSSQTATISLADGTEAFKCYVSQQAAYLYENTTFTCTAQNDLSSYNTIDGSITFSLNFSDGGSSYEYELENAKFFKSGPMLVKLGNQMSDVVNFDPAAFTENVFHSGRSTGYGSFESYHLGMYCPNGYFLGGTEKIDYDSSNNNVDLDCSSVQVYSSNDFNDWWFPQSYNDTNADVTCFGSNLWITLDEKLYDGEMLWVNALQSLPANVNTIDHALEFQYTCLDTIANTTYATQFSTTREFIVYQGRNLGTASAKSSFISTTTTDLTSINTSAYSTGSISTVETGNRTTSEVISHVVTTSTKLSPTATTSLTIAQTSIYSTDSNITVGTDIHTTSEVISDVETISRETASTVVAAPTSTTGWTGAMNTYISQFTSSSFATINSTPIISSSAVFETSDASIVNVHTENITNTAAVPSEEPTFVNATRNSLNSFCSSKQPSSPSSYTSSPLVSSLSVSKTLLSTSFTPSVPTSNTYIKTKNTGYFEHTALTTSSVGLNSFSETAVSSQGTKIDTFLVSSLIAYPSSASGSQLSGIQQNFTSTSLMISTYEGKASIFFSAELGSIIFLLLSYLLF
What is the function of this protein?
Cell surface glycoprotein promoting cell-cell contact to facilitate mating.  S. cerevisiae A and alpha cells express the complementary cell surface glycoproteins A-agglutinin and alpha-, respectively, which interact with one another to promote cellular aggregation during mating.
What are the official names of this protein?
Alpha-agglutinin, AG-alpha-1.
What is the protein family that this protein belongs to?
To C.albicans ALS1.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Lipid-anchor, GPI- anchor. Note=Covalently-linked GPI-modified cell wall protein (GPI- CWP).
Protein: CYT1_ACTCC
Sequence: MVPKPLSLLLLLLLALSAAVVGGRKRVAAGGWRPIENLNSAEVQDVAQFAVSEHNKQANDELQYQSVVRGYTQVVAGTNYRLVIAAKDGAVVGNYEAVVWDKPWMHFRNLTSFRKV
What is the function of this protein?
Specific inhibitor of papain family cysteine proteinases.
What are the official names of this protein?
Cysteine proteinase inhibitor 1, KCPI1, Phytocystatin.
What is the protein family that this protein belongs to?
Belongs to the cystatin family. Phytocystatin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1314_RICFE
Sequence: MKKLLLIAATSATILSSSISFAVDMGNDWYLRIDAGAAMFNKEKDKATGVKLKSNTTVPVDLGIGYYISENFRADLTLGTIIGGKLKKSGAATNAPFTGTNISASHKPTITRLLINGYVDLTNFDMFDVFAGAGVGPALVKEKITYNGITGLSSNTKNRTNISYKLTLGTSAQIADGVKAELAYSWIDDGRTKSKNVIYQGTSVSTGGMRYQSHNLTAGIRFDI
What are the official names of this protein?
Putative adhesin RF_1314.
Protein: RSMC_SHEB5
Sequence: MLTNPSQVIIRNQDSLSQHKVLVLNHEADLLPKALLDVAASVDALALDYHHYLHLAPHANTKLRCYFGHDLPHQDPLEREKYDTVIVYFPKAKPLAPYLFNLAANHLVPNGQLLVVGENKGGIKSLVKLLPEYFATGMKLDNARHCLLFGSSLEGSAPAMKLSDWVSQYQLTTPQGEISICNLVGVFSEKRLDLGTELLLSHLPTLSGRVLDFGCGAGVIAAALLKAQPSLSLECVDINAMALASCELTLAANGMTAKVYPSDGLAQTTGKFNGIISNPPFHDGLASTTSIAQNFVTDSAKQLQHNGIWQIVANRHLPYSDIIAAEFGQLKVVADNNKYKLYYFQHK
What is the function of this protein?
Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase C, 16S rRNA m2G1207 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RsmC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF1_YERPA
Sequence: MAKEDNIEMQGTVLDTLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVTVELTPYDLSKGRIVFRSR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL33_NITMU
Sequence: MREKIKLESSAGTGHFYTTTKNKRTTPEKIEITKFDPVARKHVKYKETKLK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: YJY3_SCHPO
Sequence: MNPKRLRITGPEDLTDAYDTMPFRCLNGSMPPKTPLNFVFKENDSHVSNGVGLKKDCIESIDDLNLDDWSEQQESILLMCYENELQKPITCTPMGPICLWAPPEPVLRSVHNTLLKMGWSISEKKMKKKLLELLAKNKKRRTMRKLEIDTNLSFLTDVQRDSPIIENAPLQSPFHF
What are the official names of this protein?
Uncharacterized protein C132.03.
Protein: DTD_STAEQ
Sequence: MKIIVQRVKNARVTNDTIDNQINKGYCLLVGVGQNSTEEDVKVIARKIAHARLFEDENDKLNLNIQQVEGEILSVSQFTIYADVKKGNRPGFSNSKAPEQAKDLYQKFNKELEGYGLIVKTGEFGTHMNVEINNDGPVTLIYESQDGKII
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASSY_ECO57
Sequence: MTTILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEEDYDAIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNTTPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDTDFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEYLNSSVKIVNPIMGVKFWDESVKIPAEEVTVRFEQGHPVALNGKTFSDDVEMMLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHAHGRQLGRLLYQGRWFDSQALMLRDSLQRWVASQITGEVTLELRRGNDYSILNTVSENLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLFGYAKTGLLSSSAASGVPQMENLENKGQ
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_METB6
Sequence: MAHHNGPRKKTRYKFKKELRQRGLPPVTSVIQQFEVGEKVHIVVNSSVQKGMPHRRFHGLTGTVIGKRGRAWMLTIHDGNAEKTVIARPQHLKAQK
What are the official names of this protein?
50S ribosomal protein L21e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL21 family.
Protein: ALG14_YEAST
Sequence: MKTAYLASLVLIVSTAYVIRLIAILPFFHTQAGTEKDTKDGVNLLKIRKSSKKPLKIFVFLGSGGHTGEMIRLLENYQDLLLGKSIVYLGYSDEASRQRFAHFIKKFGHCKVKYYEFMKAREVKATLLQSVKTIIGTLVQSFVHVVRIRFAMCGSPHLFLLNGPGTCCIISFWLKIMELLLPLLGSSHIVYVESLARINTPSLTGKILYWVVDEFIVQWQELRDNYLPRSKWFGILV
What is the function of this protein?
Involved in protein N-glycosylation.  Essential for the second step of the dolichol-linked oligosaccharide pathway.  Anchors the catalytic subunit ALG13 to the ER.
What are the official names of this protein?
UDP-N-acetylglucosamine transferase subunit ALG14, Asparagine-linked glycosylation protein 14.
What is the protein family that this protein belongs to?
Belongs to the ALG14 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus membrane; Single- pass membrane protein.
Protein: CCMF_BRADU
Sequence: MIAESGHYALVLALGLALIQSIVPLIGARLRDDALMSVARSTALAQLLFVGASFVALVMLHVNSDFSVANVYENSHSMKPLLYKITGVWGNHEGSMLLWVSILALFGGLVAAFGNNLPLSLRAHVLAVQAWIASAFYLFILVTSNPFLRIANPPIEGRDLNPVLQDIGLAVHPPMLYLGYVGFSISFSFAIAALMEGRIDAAWARWVRPWTLVAWIFLTLGIAMGSYWAYYELGWGGWWFWDPVENASLMPWLAGTALLHSALVMEKRNALKVWTILLSILTFSLSLLGTFLVRSGVITSVHAFATDPTRGVFILLILCLFIGGSLSLFAGRATSLKQGGLFAPISREGALVLNNLLLTVACAVVLFGTLYPLAMEMLADFKMSVGAPFYNLTFAPLFALLLLAVPFGPMLAWKRGDLLGVTQRLLAAGVAGLVVVAIVWAWTRGGSALAPLAIGLGVFVIAGAVTDLVERTGLVRLPLATALQRARGLPRSAWGAALAHAGLGVALIGIVCETTWNSEYIATMKRSDVAHVAGYDVKLDGLFQRQGPNYREMIAEFNVSRDGETLSVMTPSKRSFTTRGSSTTEAALLTRGASQLYISLGDANAEGAIAVRIYHKPLVLLIWWGPVLMAFGGVLSLSDRRLRVGAPKPARAKQRLQPAE
What is the function of this protein?
Required for the biogenesis of c-type cytochromes.  Possible subunit of a heme lyase.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CycK.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ISPE_BACP2
Sequence: MRILEKAPAKINLSLDVHGKRPDGYHEVEMVMTTIDLADRLELTELDKDEIRVSSHNRFVPDDQRNLAYQAAKLLKTRFGIQKGVSIVITKTIPVAAGLAGGSSDAAAALRGLNRLWKLNLTLDELAELGAEIGSDVSFCVHGGTALATGRGEKLKHIATPPHCWVILAKPVIGVSTAEVYRQYDASKVEHPNVERMIEAIEAKDYKEMCGSLGNVLESVTLKMYPEVDMIKRQMKRFGADAVLMSGSGPTVFGLIQYESKVQRIYNGLRGFCDQVYAVRMIGEQNALD
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: EFP_PROMA
Sequence: MISSNDFRTGTTIELDGAVWRVVEFLHVKPGKGSAFVRTKLKAVQAGNVVEKTFRAGEMVPQALLEKATLQHTYMESGDYVFMDMSTYEETRLTANQIGDSRKYLKEGMEVNVVSWNEKPLEVELPNSVVLEVKETDPGVKGDTATGGTKPAILETGAQIMVPLFISVGEKIKVDTRNDSYLGREN
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPHB_THEVO
Sequence: MLNIIGIGLRGTGSLTLDEFDALRTSDIVYLDIYTSIGPKDILEKLRNIADREIIPADRNMIESESILKDAEKLNVSLLVIGDGLTATTHNQLRYSAMEKGIKVKIFENASAVNTAAGKIGLLHYKVGPPVSLPFVSSNFFPLSVIDKVKRNYDSGLHTPILIDLKDGQNMPFASAWNIIMEMQKRKGVCNNRRKCMRCLEAFISG
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine.  The three successive methylation reactions represent the second step of diphthamide biosynthesis.
What are the official names of this protein?
Diphthine synthase, Diphthamide biosynthesis methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the diphthine synthase family.
Protein: RPOC_PSEA7
Sequence: MKDLLNLLKNQGQIEEFDAIRIGLASPEMIRSWSFGEVKKPETINYRTFKPERDGLFCAKIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVALAKVRRERMGHIELASPVAHIWFLKSLPSRIGLLLDMTLRDIERVLYFESYVVIDPGMTTLEKGQLLNDEQYFEALEEFGDDFDARMGAEAVHELLNAIDLEHEIGRLREEIPQTNSETKIKKLSKRLKLMEAFQGSGNKPEWMVLTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPTLRLHQCGLPKKMALELFKPFIFGKLEGRGMATTIKAAKKMVERELPEVWDVLAEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVMGLYYMTREAINAKGEGMAFADLQEVDRAYRSGQASLHARVKVRINEKVKGEDGQLTANTRIVDTTVGRALLFQVVPAGLPFDVVNQSMKKKAISKLINHCYRVVGLKDTVIFADQLMYTGFAYSTISGVSIGVNDFVIPDEKARIINAATDEVKEIESQYASGLVTQGEKYNKVIDLWSKANDEVSKAMMANLSKEKVVDREGKEVDQESFNSMYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEIDCGTEHGLLMSPHIEGGDVVEPLGERVLGRVIARDVFKPGSDEVIVPAGTLIDEKWVDFLEVMSVDEVVVRSPITCETRHGICAMCYGRDLARGHRVNIGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRTSAADNVQVKNGGTIRLHNLKHVVRADGALVAVSRSGELAVADDFGRERERYKLPYGAVISVKEGDKVDPGAIVAKWDPHTHPIVTEVDGTVAFVGMEEGITVKRQTDELTGLTNIEVMDPKDRPAAGKDIRPAVKLIDAAGKDLLLPGTDVPAQYFLPANALVNLTDGAKVSIGDVVARIPQETSKTRDITGGLPRVADLFEARRPKEPSILAEISGTISFGKETKGKRRLVITPNDGSDPYEELIPKWRHLNVFEGEQVNRGEVISDGPSNPHDILRLLGVSSLAKYIVNEIQDVYRLQGVKINDKHIETILRQMLRKVEVSESGDSSFIKGDQVELTQVLEENEQLGTEDKFPAKYERVLLGITKASLSTESFISAASFQETTRVLTEAAVTGKRDFLRGLKENVVVGRLIPAGTGLAYHSERKRQRDLGKPQRVSASEAEAALTEALNSSGN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: SEC9_YEAST
Sequence: MGLKKFFKIKPPEEATPEQNKDTLMELGISVKNPSKKRKEKFAAYGKFANDKAEDKVYAPPGYEQYARPQDELEDLNASPLDANANEATAGSNRGSSGTQDLGNGAESNSMQDPYAIENDDYRYDDDPYARFQANKSNGRGSVNAAPYGDYGGGYNGTSLNSYNNDGPYSNQNTSNSWVNANGRNSLNHSNSTLNVGPSRQTRQPPVSTSTNSLSLDQRSPLANPMQEKRNPYADMNSYGGAYDSNTNRSSGTRQGSSKNANPYASMANDSYSNGNLNRSANPYSSRSVRQPQSQQAPMTYTPSFIASDEAARNSEVDLNEEPRTGEFDFEEVYADKSAENRAALDEPDLNAVMTNEDSIDLNASEVDHSSRQQQQQQWFMDEQQQQQQHFNATNNQYGDQRGYKTFEEIQKEEEARQQQEEDEAVDEIKQEIKFTKQSSVASTRNTLKMAQDAERAGMNTLGMLGHQSEQLNNVEGNLDLMKVQNKVADEKVAELKKLNRSILAVHVSNPFNSKRRRREREEQLKNRKIEEKLMREQTSQQLSQSTQRIEGAMNANNNISEVRERYQRKNVLEKAKRYQFENDEEDDEMELEIDRNLDQIQQVSNRLKKMALTTGKELDSQQKRLNNIEESTDDLDINLHMNTNRLAGIR
What is the function of this protein?
Component of a SNARE complex that may be the effector of SEC4 function in exocytosis.
What are the official names of this protein?
Protein transport protein SEC9.
What is the protein family that this protein belongs to?
Belongs to the SNAP-25 family.
Protein: PDXJ_CUPPJ
Sequence: MIFHANPGVIDLGINIDHVATLRNARGTVYPDPIEAALQAEEAGADLITLHLREDRRHIRDADVRALRPQLATRMNLECAITQEMLDIACEIRPQDVCLVPERREEVTTEGGLDVAGRFGQVSSACKQLAAAGIRVSLFIDADADQIAAAAACGAPVIELHTGRYADAHTPDELAIEFRRVADGVDAGIRHGLVVNAGHGLHYTNVQPIAALAGIKELNIGHAVVAHAVFVGWQNAVREMKAIMVAARLGTRYPAAGKPA
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MELA_ASPTE
Sequence: MQPSLIPSLLETAAARNGDGRVILYSQGNREDPRSITYRDLLETASKASVAVHNHQNYTPGAAVLLHFNNHLDNIVWFWAVLLAGCIPAITPAFSNNPVQRVANLEHLSSTLITDWCLTSQALLAEFAGQDAIEPVSVETLGWEKASPASNTASVKAKPTDTALLLFTSGSTGKSKAVCLSHFQIVSAIAGKLSVVPLPEQSSFLNWVGLDHVAAIIEIHLQALYADLDQVHVPGSDVISDPIWFLDLMATHRVSRTFAPNFFLARIRDALVQNARSASPRQWDLSGLRYVASGGEANTTKTCDDLSQLLKSFGAPLNVIVPGFGMTETCAGAIFNTNCPDYDKKHGLEYTSVGSCMPGIFMRVTNQQGDPLPPGEMGSLELAGPVVFRQYLNNPAATQESFTMDGWFKTGDCGTLDENGYLVLGGRAKETIIINGVKYSPHEIETAVEEHNIKGLSRSFTCCFSSLSPGAETEEIVLVYLPTYAPEDIPARAATADAISKVVLMSTGSRPHIIPLEQALLPKSTLGKLSRSKIKAAYERGEYRTHDSINRSLIARHRQATRASPKNDFEKGLLEIFLRSFKISEDEFDVQTPIFDVGIDSIELINLKRDIEQHLGFADATIPIIILLENTTVRELAAALDNLYRPKEYNPVVTLQAHGDKNPLWLVHPGAGEVLIFINLAKFITDRPVYALRARGFDEGEKPFDSIEDAVTSYYNGVKSKQPHGPYALAGYCYGSMLAFEVAKKLEENGDEVRFVGSFNLPPHIKMRMRELDWKECLLHLAYFLDLITQKRSRELAVELDGLDQDTILQAIIDEADKERYAQLSLSRPFLSRWADVAYELHRIAGDYDPDGRVASMDVFFSIPLAIAAASKSEWRNVHLSQWDDFTRSHVRFHDVPGEHYSMIGPEHVFAFQKILRSALAERGM
What is the function of this protein?
Nonribosomal peptide synthase; part of the gene cluster that mediates the biosynthesis of Asp-melanin, a pigment that confers resistance against UV light and hampers phagocytosis by soil amoeba (PubMed:23841722, PubMed:27133313, PubMed:29270299).  The nonribosomal peptide synthase melA converts 4-hydroxyphenylpyruvate (4-HPPA) to aspulvinone E (PubMed:27133313, PubMed:29270299).  The tyrosinase tyrP then performs hydroxylations of both aromatic moieties of aspulvinone E (PubMed:27133313).  The product of tyrP is highly unstable, and, due to the high reactivity of methides and ortho-diquinones, the polymeric Asp-melanin forms spontaneously (PubMed:27133313).
What are the official names of this protein?
Aspulvinone E synthetase melA, Nonribosomal peptide synthetase melA.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXA_BURCH
Sequence: MTRIHPTAIVEPGAQIDESVEIGPYAIVGPHVTIGARTTIGSHSVIEGHTTLGEDNRIGHYASVGGRPQDMKYKDEPTKLVIGNRNTIREFTTIHTGTVQDVGVTTLGDDNWIMAYVHIGHDCRVGNNVILSSNAQMAGHVEIGDFAIIGGMSGVHQFVRIGAHSMLGGASALVQDIPPFVIAAGNKAEPHGINVEGLRRRGFSADAISALRSAYRVLYKNGLSLEEAKVQLRELAEAGGDGDAPVTALVEFIDASQRGIIR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NKG7_BOVIN
Sequence: MEPCRSLALLTSSLGLVSLLVAVSTNFWFAARGPGFSSHSGLWPSKDQVSVAGYIHVTQSFCILAVLWGLISTAFLVMSCIPSLSAPGRGPIVSTFMGFAGALSLIVAMTVYTIERWNQPANPQVQSFFSWSFYLGWVSTLLFLCTGGLSLGAHCTTHRPDYEAV
What is the function of this protein?
Regulates cytotoxic granule exocytosis in effector lymphocytes, thus acting as a critical mediator of inflammation in a broad range of infectious and non-infectious diseases (By similarity).  Essential for cytotoxic degranulation of natural killer (NK) cells and CD8(+) T-cells and for the activation of CD4(+) T-cells following infection (By similarity).  Plays a critical role in CD8(+) T-cell and NK cell-mediated cytolysis of target cells and contributes to the cytolytic activity via the perforin/granzyme pathway by enhancing exocytosis of LAMP1-carrying lytic granules (By similarity).  Contributes to NK cell-mediated control of cancer metastasis (By similarity).
What are the official names of this protein?
Protein NKG7, Natural killer cell protein 7.
What is the protein family that this protein belongs to?
Belongs to the PMP-22/EMP/MP20 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytolytic granule membrane; Multi-pass membrane protein.
Protein: METN_SHISS
Sequence: MIKLSNITKVFHQGTRTIQALNNVSLHVPAGQIYGVIGASGAGKSTLIRCVNLLERPTEGSVLVDGQELTTLSESELTKARRQIGMIFQHFNLLSSRTVFGNVALPLELDNTPKDEIKRRVTELLSLVGLGDKHDSYPSNLSGGQKQRVAIARALASNPKVLLCDEATSALDPATTRSILELLKDINRRLGLTILLITHEMDVVKRICDCVAVISNGELIEQDTVSEVFSHPKTPLAQKFIQSTLHLDIPEDYQERLQAEPFTDCVPMLRLEFTGQSVDAPLLSETARRFNVNNNIISAQMDYAGGVKFGIMLTEMHGTQQDTQAAIAWLQEHHVKVEVLGYV
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.