PharMolix/UniProtQA huggingface dataset:
Protein: PFF1_ASHGO
Sequence: MKLTKAVFRFRRTNLSTLLVITYLVITTLYVWDHFRYHFTLPSDYNYAQMLADAWLDLEIITQYPHPYASHANDKVHDYLLDRVKEITRDSMFAEISDDYGMGLRTLFRQEDAISGTKESTVVYYESSNVLARVQGRNSALDGLLLSAHYDSVPSGYGATDDGMGVVSMLAILTHYVKNQPERTLVFNFNNNQEFGLAGASAFFEHPWSKEISYVINLEGTGAGGKAVLFRTSDVSTAQVYAEAVRQQPFGNSMYQQGFYNGHIGTETDFQVYEDQGLRGWDIAFYRPRNLYHTAKDTVLYTSKQALWHMLHTALQLTDYMAINKPDMEDTSNAVYFDLFGKWFVVWSARSLFYWNCIILALFPSILAILFLVAYDMQLLKFNFWDAMLRLPVSVCLAYFCVKLFQVLVGQLNPYVFSRDYVSPILAEASMFIFMNYVILSSWERLRPLRDFKTVALVEVSMVLWIYLISVTRWLRDSDYTATGLYPFTIGYTFVSIGAIIGVFCATFKAKLNPEDDSYVGDSKVDIEQQQMLMQHQYQQHSQKHSNQHSPHHSTHHSAQHSVHHSPRQSIHQVPSSEQRQRDASETPHVIISVDHTAGHQEDSEVTPLLNTGTVAPFPKPVPERVSRKSFLRNVVTSILNYDWSIQFMVVTPWVTYFTWICLDLIMGAMNQTIQESAKGTTFVTHMALIGSLLLSLPMLPFTYKLHSFAGMLFLLLAVTTAVWTIVAPPFTESSPLKLRFLQTIDLDKNNSSSVYLYGRERTFMEPILDDIPSVTKYRCVEYAGDGVDICEYNGMPPRMFNNHHEAESDWTKIMTLEILKDDRNSTSRTPYQPITAELKINVEENRVCTLNFNSTAFKNWKQGVSPLREVVILHENPSSNVTPSFYNTAMKNGYYQDEFGNDHYRWNNGITELQLHKLDFKRGYYKIGLEWIPQLLYRGYDPATSSSEEDDALGVSVTCYWGEYDTDSITDGFATTNVPAYDELRKYSPKNIIYSSKEKGMVSVTKYVEL
What is the function of this protein?
May be involved in vacuolar sorting and osmoregulation.
What are the official names of this protein?
Vacuolar membrane protease, FXNA-related family protease 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: TPST_DROME
Sequence: MRLPYRNKKVTLWVLFGIIVITMFLFKFTELRPTCLFKVDAANELSSQMVRVEKYLTDDNQRVYSYNREMPLIFIGGVPRSGTTLMRAMLDAHPDVRCGQETRVIPRILQLRSHWLKSEKESLRLQEAGITKEVMNSAIAQFCLEIIAKHGEPAPRLCNKDPLTLKMGSYVIELFPNAKFLFMVRDGRATVHSIISRKVTITGFDLSSYRQCMQKWNHAIEVMHEQCRDIGKDRCMMVYYEQLVLHPEEWMRKILKFLDVPWNDAVLHHEEFINKPNGVPLSKVERSSDQVIKPVNLEAMSKWVGQIPGDVVRDMADIAPMLSVLGYDPYANPPDYGKPDAWVQDNTSKLKANRMLWESKAKQVLQMSSSEDDNTNTIINNSNNKDNNNNQYTINKIIPEQHSRQRQHVQQQHLQQQQQQHLQQQQHQRQQQQQQREEESESEREAEPDREQQLLHQKPKDVITIKQLPLAGSNNNNINNNINNNNNNNNIMEDPMADT
What is the function of this protein?
Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides (By similarity).  Has a role in protein secretion.
What are the official names of this protein?
Protein-tyrosine sulfotransferase, Transport and Golgi organization protein 13, Tango-13, Tyrosylprotein sulfotransferase.
What is the protein family that this protein belongs to?
Belongs to the protein sulfotransferase family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: PAX_I83A5
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDFHFIDERGDSIIVEVGDPNALLKHRFEIIEGRDRNMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFVEIGVTRREIHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFVSPREAKRQLKKDLKLQEPCAGSPTKVSHRTSPALKTLEPMWMDSNRTAALRASFLKCPKK
What is the function of this protein?
May play a role in the modulation of host immune response.
What are the official names of this protein?
Protein PA-X.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA-X family.
Protein: AAEA_SHIDS
Sequence: MKTLIRKFSRTAITVVLVILAFIAIFNAWVYYTESPWTRDARFSADVVAIAPDVSGLITQVNVHDNQLVKKGQVLFTIDQPRYQKALEEAQADVAYYQVLAQEKRQEAGRRNRLGVQAMSREEIDQANNVLQTVLHQLAKAQATRDLAKLDLERTVIRAPADGWVTNLNVYTGEFITRGSTAVALVKQNSFYVLAYMEETKLEGVRPGYRAEITPLGSNKVLKGTVDSVAAGVTNASSTRDDKGMATIDSNLEWVRLAQRVPVRIRLDNQQENIWPAGTTATVVVTGKQDRDESQDSFFRKMAHRLREFG
What is the function of this protein?
Forms an efflux pump with AaeB.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeA, pHBA efflux pump protein A.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: Y876_RICBR
Sequence: MLTIISSAKTLNFELIAFKGELTSPAFPKITNQLLAIVKNYSEVQLSKTMDISEKLAHLNKERFQNFEKQDSKAAIFAYAGDVFNNIQSKNLSEDAVNFLQSHLLIISGLYGALKPLDAIKPYRLEMAAKLNEINDLSKFWQDEITNYINHTLEHHKHKYLLNLASQEYSSVLNQDKLKYPIINIHFKENRNGKLATIGINAKKARGNMVNFIANNLIDSPDLLKEFSYLGYKYSSKDSLNNDLVFVK
What are the official names of this protein?
UPF0246 protein RBE_0876.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: AV238_PHYSO
Sequence: MRGVFFVAVAVAIFARSSAEAKLLSEAAPGLAADAVISGESRERFLRVADSEDDDLAAPADDGKTEERAPKFKSLSEINKKLDEEVMVHVSKILGNMGAIHADNIAKARAALEAAHKSGDITDKQLAAGLAKLV
What is the function of this protein?
Effector that, due to the lack of a histidine residue at position 79, is not able to induce cell death in tomato, tobacco, eggplant, potato, or in A. thaliana.
What are the official names of this protein?
RxLR effector protein Avh238, Avirulence homolog protein 238.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Host nucleus.
Protein: THP3_YEAST
Sequence: MQNPYGHFTNNTTEDREASSQGGPFGQSLNRPLDYAGSFPSLTYNNNNFIANQQPSLPLPEPRLSWNNVNQVSNPLMVTPLPGLQKRMNKNIKKKLPRVSKKASALSNGVSGNVMSNSNIVGHGAVGSASGWKVEMGGSDELERRKRRAERFSQGPSATTNSNDNLNEDFANLNAISSKSHQYDKKIHVVGRCQTLEKSYLRLTSEPNPDLIRPPNILQKMYCLLMDKYQSKTATYTYLCDQFKSMRQDLRVQMIENSFTIKVYQTHARIALENGDLGEFNQCQNRIMALFENPTIPKKSYSEFICYSVLYSMLTEDYPSISHLKLKLIDDGSSEILEDEHVKMIFELSDMKLVGNYHYFMKNYLKLHKFEKCLINSFLNLEKLIFLTIICKSYNQVNLDFVKSEFNFNSIEETTNFLNEQNLTEFILNKQITDSNGKSSNIKILNTKGCRVQLIQNYMKSKKIDIKGQK
What is the function of this protein?
Forms a complex with CSN12 that is recruited to transcribed genes and required for transcription elongation.  May also be involved in pre-mRNA splicing.
What are the official names of this protein?
Protein THP3, THO-related protein 3.
What is the protein family that this protein belongs to?
Belongs to the THP3 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ASNA_STRPC
Sequence: MKKSFIHQQEEISFVKNTFTQYLIAKLDVVEVQGPILSRVGDGMQDNLSGTENPVSVNVLKIPNATFEVVHSLAKWKRHTLARFGFNEGEGLVVNMKALRPDEDSLDQTHSVYVDQWDWEKVIPDGKRNLAYLKETVETIYKVIRLTELAVEARYDIEAVLPKKITFIHTEELVAKYPDLTPKERENAITKEFGAVFLIGIGGVLPDGKPHDGRAPDYDDWTTETENGYHGLNGDILVWNDQLGSAFELSSMGIRVDEEALKRQVEMTGDQDRLAFDWHKSLLNGLFPLTIGGGIGQSRMVMFLLRKKHIGEVQTSVWPQEVRDSYDNIL
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAND_CLONN
Sequence: MELNMLKSKIHRVTVTQAELSYVGSITIDKALMKAANILEYEKVQIVDIDNGARFETYVIPGEENSKVICLNGAAARCVQVGDKVIIMCYCSMDEQEAKDYKPIVVFANEDNTINKISNYERN
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NALF2_XENTR
Sequence: MIRGAWMYPREDEAVLKICWEPRHSDKPCADSERAQRWRMSLASLLFFTVLLSNHLWLVSAGAKARGSFTFSLQPANSSLLPPQSFPGEGRGCWDTFLSNLTKSAAQPPHCTGVRSTHLDTACAKLHYLQRHRGSFSPSYPQPSSWSSSYWSYPPSSFSSKRNFLKAYFRNYTLSFCDTYTILDLLLGMSNPDSLDCSLESLMEDFVGAAAASPALIEGEVCSSCIQAYQRLDQHAQEKYEEFDFVLEKYLQSGEYSVRSCVGDCKAVYKAWLCSEYFNVTQRQCRHRIPCKQYCLEVQTRCPFMLPDNDDLIYGGLPGFICTDMLENHMSNTEAECCDVRWHSCKTQGSGNHNTSTKSTDSRFKYYPHHQHHRDHHLHPYHHQHHQSLLPVSAGSRLGNTRLRLCVLVLMLLHTMASFSVVQNGVTLEPLPGLDDSSSHEE
What is the function of this protein?
Probable component of the NALCN channel complex, a channel that regulates the resting membrane potential and controls neuronal excitability.
What are the official names of this protein?
NALCN channel auxiliary factor 2, Transmembrane protein FAM155B.
What is the protein family that this protein belongs to?
Belongs to the NALF family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: KC1G1_CHICK
Sequence: MDHPNREKDERQRTTKGMPGRSGHGSRPSSSASSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAAEGLPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRQGNKKDHVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPVEVLCENFPEEMATYLRYVRRLDFFERPDYDYLRTIFTELFEKKGYTFDYAYDWVGRPIPTPVGSVHVDSGTSAITRDSHVHRDRPSQQALRNQASSDRRGEWEIQPSRQTNTSYLTSHLAADRHGGSVQVVSSTNGELNVDDPTGAHSNAPITAQAEVEVVEEAKCCCFFKRKRKKTAQRHK
What is the function of this protein?
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates.  It can phosphorylate a large number of proteins.  Participates in Wnt signaling (By similarity).
What are the official names of this protein?
Casein kinase I isoform gamma-1, CKI-gamma 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECB_SALSV
Sequence: MSEQNNTEMAFQIQRIYTKDVSFEAPNAPHVFQKDWQPEVKLDLDTASSQLADDVYEVVLRVTVTASLGEETAFLCEVQQAGIFSISGIEGTQMAHCLGAYCPNILFPYARECITSLVSRGTFPQLNLAPVNFDALFMNYLQQQAGEGTEEHQDA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR7_SHIBS
Sequence: MQKQAELYRGKAKTVYSTENPDLLVLEFRNDTSAGDGARIEQFDRKGMVNNKFNYFIMSKLAEAGIPTQMERLLSDTECLVKKLDMVPVECVVRNRAAGSLVKRLGIEEGIELNPPLFDLFLKNDAMHDPMVNESYCETFGWVSKENLARMKELTYKANDVLKKRFDDAGLILVDFKLEFGLYKGEVVLGDEFSPDGSRLWDKETLEKMDKDRFRQSLGGLIEAYEAVARRLGVQLD
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: T184A_MOUSE
Sequence: MRNASGFLKTAGAPLVSATWLPPSPPPAMPTVAAGPQMERVDNGSQGAPQLFLTSALARGVSGVFVWTALLLTGHQIYSHLRSYTAPREQRFVIRLLFIVPIYAFDSWLSLLLLGGHPYYVYFDSVRDCYEAFVIYSFLTLCFQYLGGESAIMAEIRGKPIRSSCFYGTCCLRGMSYSITFLRFCKQATLQFCIVKPVMALITIILQAFDKYHDGDFNIHSGYLYVTLVYNASVSLALYALFLFYFATRDLLRPFEPVLKFLTIKAIIFLSFWQGMLLAILERCGVIPEVQAVDGTRVGAGTLAAGYQNFLICVEMLFASLALRYAFPSQVYSEKKNSPVPPAPMQSISSGLKETISPQDIVQDAIHNFSPAYQQYTQQSTHEAPGPGQGGHPAPSTHPGPASGSGGGKKSRNIEKRMLIPSEDL
What is the function of this protein?
Acts as a heparin receptor in vascular cells (By similarity).  May be involved in vesicle transport in exocrine cells and Sertoli cells (PubMed:18321981, PubMed:19097053).
What are the official names of this protein?
Transmembrane protein 184A, Sexually dimorphic expressed in male gonads 1.
What is the protein family that this protein belongs to?
Belongs to the TMEM184 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasm, perinuclear region. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein. Endosome. Cytoplasmic vesicle, secretory vesicle membrane. Note=Colocalizes with the secretory granule marker VAMP2 in pancreatic acinar cells (PubMed:19097053).
Protein: GH39_ARATH
Sequence: MDVMKLDHDSVLKELERITSKAAEVQDNILRGILERNKDTEYLSKYMNGSKDVLEFKRAVPIIIYKDIYPYIQRIANGEDSSLITGHSITEILCSSGTSAGEPKLMPTIPEDLDRRTFLYNLIIPIVNKYITGLDKGKAMYLNFVKAETSTPCGLPIRAVLTSYYKSKHFQCRPYDPFNDLTSPIQTILCEDSNQSMYCQLLAGLIHRHKVMRLGAVFASAFLRAISYLEKKWSQLCEDIRTGSLNPMITDPGCQMAMSCLLMSPNPELASEIEEICGRSSWKGILCQLWPKAKFIEAVVTGSMAQYIPALEFFSQGKIPLVCPMYASSETYFGVNVEPLSKPSDVVFTLLPNMCYFEFIPLGKNGTLSFDLDDDEQVPCDKVVDLVNVKLGRYYELVVTTFAGLYRYRIGDVLQVAGFYNGAPQFRFICRRNVVLSIDLDKTNEEDLHRSITLAKKKLGSNAFLAEYTSYADTSSVPGHYVLFWEIQGHLEPKLMEECCVAVEEELDYIYRQCRTKERSIGALEIRVVKPGTFEKLMDLIISQGGSFNQYKTPRCVKSNSATFKLLNGHVMASFFSPRDPTWVP
What is the function of this protein?
Catalyzes the synthesis of indole-3-acetic acid (IAA)-amino acid conjugates, providing a mechanism for the plant to cope with the presence of excess auxin.
What are the official names of this protein?
Putative indole-3-acetic acid-amido synthetase GH3.9, Auxin-responsive GH3-like protein 9, AtGH3-9.
What is the protein family that this protein belongs to?
Belongs to the IAA-amido conjugating enzyme family.
Protein: CGL3_COPC7
Sequence: MFHILRLESTVDLSEPLKDNGIIVFQSDKLDLEPSPNLGPTGIDNTNVNLINAKGDVLLHIGIRRRENAFVFNSIPYGESRGPEERIPLEGTFGDRRDPSITVFDHPDRYQIMIDYKTVYYYKKRLEGRCEKVSYKINEGQTPPFSDVLGVTVLYFANVMPRAN
What is the function of this protein?
Binds lactose.  May play a role in fruiting body formation (By similarity).
What are the official names of this protein?
Galectin-3, Cgl-III, Galectin III.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Secreted, cell wall.
Protein: FLGI_HELPG
Sequence: MKRVFLWLIFVLAFHKLLAEKIGDIASVVGVRDNQLIGYGLVIGLNGTGDKSGSKFTMQSISNMLESVNVKISADDIKSKNVAAVMITASLPPFARQGDKIDIHISSIGDAKSIQGGTLVMTPLNAVDGNIYALAQGAITSGNSNNLLSANIINGATIEREVSYDLFHKNAMTLSLKNPNFKNAIQVQNTLNKVFGNKVAIALDPKTIQITRPERFSMVEFLALVQEIPINYSAKNKIIVDEKSGTIVSGVDIIVHPIVVTSQDITLKITKEPLNDSKNTQDLDNNMSLDTAHNTLSSNGKNITIAGVVKALQKIGVSAKGMVSILQALKKSGAISAEMEIL
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: CHDH_HUMAN
Sequence: MWCLLRGLGRPGALARGALGQQQSLGARALASAGSESRDEYSYVVVGAGSAGCVLAGRLTEDPAERVLLLEAGPKDVLAGSKRLSWKIHMPAALVANLCDDRYNWCYHTEVQRGLDGRVLYWPRGRVWGGSSSLNAMVYVRGHAEDYERWQRQGARGWDYAHCLPYFRKAQGHELGASRYRGADGPLRVSRGKTNHPLHCAFLEATQQAGYPLTEDMNGFQQEGFGWMDMTIHEGKRWSAACAYLHPALSRTNLKAEAETLVSRVLFEGTRAVGVEYVKNGQSHRAYASKEVILSGGAINSPQLLMLSGIGNADDLKKLGIPVVCHLPGVGQNLQDHLEIYIQQACTRPITLHSAQKPLRKVCIGLEWLWKFTGEGATAHLETGGFIRSQPGVPHPDIQFHFLPSQVIDHGRVPTQQEAYQVHVGPMRGTSVGWLKLRSANPQDHPVIQPNYLSTETDIEDFRLCVKLTREIFAQEALAPFRGKELQPGSHIQSDKEIDAFVRAKADSAYHPSCTCKMGQPSDPTAVVDPQTRVLGVENLRVVDASIMPSMVSGNLNAPTIMIAEKAADIIKGQPALWDKDVPVYKPRTLATQR
What are the official names of this protein?
Choline dehydrogenase, mitochondrial, CDH, CHD.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane.
Protein: BDCR_ECOLI
Sequence: MVTKKQSRVPGRPRRFAPEQAISAAKVLFHQKGFDAVSVAEVTDYLGINPPSLYAAFGSKAGLFSRVLNEYVGTEAIPLADILRDDRPVGECLVEVLKEAARRYSQNGGCAGCMVLEGIHSHDPQARDIAVQYYHAAETTIYDYIARRHPQRAQCVTDFMSTVMSGLSAKAREGHSIEQLCATAAMAGEAIKTILEE
What is the function of this protein?
Negatively regulates expression of bdcA.
What are the official names of this protein?
HTH-type transcriptional repressor BdcR.
Protein: CYCY_RHILV
Sequence: MGRYTLALLPLIVFGGIAHGAKMLYDQDFHGKNIAEIPSALSHQGADAEPAAARRATLPALTDAAIKGKLTLVNVFASWCLPCRDEHPVLKELAKDGRLNIVAINYKDQSDNALRFLGELGNPYQAIGIDPNGKAAIDWGVYGIPESYLVGADGTILYKRVGPSTNISLKEGLVPAMEKALGKPVS
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Also acts as a disulfide oxidoreductase in cytochromes c biogenesis.  The cysteines of apocytochromes c must be in the reduced state for covalent linkage between the two moieties to occur (By similarity).
What are the official names of this protein?
Thiol:disulfide interchange protein CycY, Cytochrome c biogenesis protein CycY.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. DsbE subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: RLMH_FRAP2
Sequence: MKIRILSLGEKPPKWVSEGYDEYKKRLSKSIPLELIELPIAKRTKTGNPKLWMEQEAKTILTKLSDSDHLVILDVNSKIISTEELAEKMQNWKFNNPNVVILIGGPDGIDQSIKNIAKEKISISKMTFPHPLVRIIIAEQLYRAYTILEGHPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UXUA_SALPB
Sequence: MKQTWRWYGPNDPVTLSDVRQAGATGVVTALHHIPNGEIWSVDEIQKRKAIVEEAGLEWSVVESVPIHEDIKTHTGQYDLWIKNYQQTLRNLAQCGIYTVCYNFMPVLDWTRTDLEYVLPDGSKALRFDQIEFAAFELHILKRPGAEADYTAEEIAQAERRFATMSEEDKARLTRNIIAGLPGAEEGYTLDQFRQHLATYKDIDKAKLREHFAYFLKAIIPVADEVGVRMAVHPDDPPRPILGLPRIVSTIEDMQWMVETVNSMANGFTMCTGSYGVRADNDLVDMIKQFGPRIYFTHLRSTLREENPKTFHEAAHLHGDVDMYEVVKAIVEEEHRRKAEGSDDLIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAEVRGVELAIQRAFFSK
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.
What are the official names of this protein?
Mannonate dehydratase, D-mannonate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the mannonate dehydratase family.
Protein: YDIB_ECOL6
Sequence: MDVTAKYELIGLMAYPIRHSLSPEMQNKALEKAGLPFTYMAFEVDNDSFPGAIEGLKALKMRGTGVSMPNKQLACEYVDELTPAAKLVGAINTIVNDDGYLRGYNTDGTGHIRAIKESGFDIKGKTMVLLGAGGASTAIGAQGAIEGLKEIKLFNRRDEFFDKALAFAQRVNENTDCVVTVTDLADQQAFAEALASADILTNGTKVGMKPLENESLVNDISLLHPGLLVTECVYNPHMTKLLQQAQQAGCKTIDGYGMLLWQGAEQFTLWTGKDFPLEYVKQVMGFGA
What is the function of this protein?
The actual biological function of YdiB remains unclear, nor is it known whether 3-dehydroshikimate or quinate represents the natural substrate.  Catalyzes the reversible NAD-dependent reduction of both 3-dehydroshikimate (DHSA) and 3-dehydroquinate to yield shikimate (SA) and quinate, respectively.  It can use both NAD or NADP for catalysis, however it has higher catalytic efficiency with NAD.
What are the official names of this protein?
Quinate/shikimate dehydrogenase, NAD-dependent shikimate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: ETV3L_HUMAN
Sequence: MHCSCLAEGIPANPGNWISGLAFPDWAYKAESSPGSRQIQLWHFILELLQKEEFRHVIAWQQGEYGEFVIKDPDEVARLWGRRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFSKLIVVNYPLWEVRAPPSPHLLLGAPALCRPALVPVGVQSELLHSMLFAHQAMVEQLTGQQTPRGPPETSGDKKGSSSSVYRLGSAPGPCRLGLCCHLGSVQGELPGVASFTPPLPPPLPSNWTCLSGPFLPPLPSEQQLPGAFKPDILLPGPRSLPGAWHFPGLPLLAGLGQGAGERLWLLSLRPEGLEVKPAPMMEAKGGLDPREVFCPETRRLKTGEESLTSPNLENLKAVWPLDPP
What is the function of this protein?
Transcriptional regulator.
What are the official names of this protein?
ETS translocation variant 3-like protein.
What is the protein family that this protein belongs to?
Belongs to the ETS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL10_STRPI
Sequence: MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRRELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSKNAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAESKEDAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: RSSA_ECHGR
Sequence: MSGGIEALELKEDDIRLMVAAKVHLGSTNANYQMQQYVYDRNDEGNHIIHLNKTWEKLLLAARAICAIENPADVVIIGGQPTWQRGALKFGHYTGTTSVPGRFTPGAFTNQIQSGFKEPRLLIVCDPKGDHQPVREGSAVNIPVIGFCNTDSPLQCVDIGIPCNNDKYSIALMLWMLAREVRRIWGLDPRSQPGDVIMDLFLMREHVDEPPEGPEGEAQEPPFEQGKFDAAEAEAPEWPAESVSPRCWNAGARFRWCWWQLDSLRCKG
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.  Binds laminin.
What are the official names of this protein?
40S ribosomal protein SA, Laminin-binding protein p40, LBP/p40.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZAPB_VIBC3
Sequence: MSFEVLEKLEAKIQTAVDTIALLQMEVEELKEEKQQLQNEAQELREAREALEQRAQQVQQEHAAWQERIRSLLGKMEDVE
What is the function of this protein?
Non-essential, abundant cell division factor that is required for proper Z-ring formation.  It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle.  Its recruitment to the Z-ring requires functional FtsA or ZipA.
What are the official names of this protein?
Cell division protein ZapB.
What is the protein family that this protein belongs to?
Belongs to the ZapB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the septum at mid- cell, in a FtsZ-like pattern.
Protein: YFH5_SCHPO
Sequence: MGNPVVIKAKKDYDCVFEPEPMSWLRLQYYRYQVTAGTYLFTYKEAFVFNTVVFIIVFLTGWAAKSIIVKLLPSLWRLSTLIPSFFASFFMSLLGKDASSQ
What are the official names of this protein?
Uncharacterized membrane protein C23A1.05.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PURL_COREF
Sequence: MSTIFNDTVEAAAENPDLEQPYAELGLKDDEYARIKEILGRRPTDAELTVYSVMWSEHCSYKSSKVHLRYFGETTTPEMAEKILAGIGENAGVVDIGDGNAVTFRVESHNHPSFVEPHQGAATGIGGIVRDIMAMGARPIAVMDQLRFGAMDNPDTQRVLPGVVSGISHYGNCLGLPNIGGETVFDDSYAGNPLVNALAVGTLKVDDLKLAFASGAGNKVMLFGSRTGLDGIGGVSVLGSASFEEGEERKLPAVQVGDPFAEKVLIECCLELYQAGVVVGIQDLGGGGLACATSELAAAGDGGMRVNLDAVPLRAEKMSAAEILASESQERMCAVVTPENVEKFKQICAKWDVTVAEIGEVTDEKDRYLVVHNGQTVIDAPASTIDEGPVYNRPVERPANQDEIQTLGGLERPDTAEGIRDAWFKLVSSPALCSRAFITEQYDRYVRGNTVQAKDANAGVLRIDEETNRGVAISADASGRYTRLDPRTGARLALAEAYRNVVSTGARPVAVTNCLNFGSPENAGVMWQFKEAVHGLADGAKEMGIPVSGGNVSFYNQTGDEPILPTPVVGVLGVLDDVEKTIGNRLPAGEQELYLLGETLDEFGGSIWQQVSGAGLSGLPPQIDLANEQRLADLLVPAADLVGAAHDLSEGGLGQTLAELAIHAGRGLDVDLTQVHEDLFTALFSESASRIVVATTRGDELVARAQELGVPVTRLGVTNDSGVITVRGGDLSVEVSVEELHDAWSNTLPEAFGHAVGANSVVE
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.