PharMolix/UniProtQA huggingface dataset:
Protein: GSE1_MOUSE
Sequence: MKGMSHEPKSPSIGMLSTATRTTATVNPLTPSPLNGALVPTGSPATSSTLSAQAAPSSSFAAALRKLAKQAEEPRGSSLSSESSPVSSPATNHSSPASTPKRVPMGPIIVPPGGHSVPSTPPVVTIAPTKTVNGVWRSESRQDSGSRGSSSGRERLLVEPPLAQEKAAGPAIPSHLLSTPYPFGLSPGSVVQDSRFQPLNLQRPVHHVVPPSTVTEDYLRSFRPYHTAEDLRMSSLPPLGLDPATAAAYYHPSYLAPHPFPHPAFRMDDSYCLSALRSPFYPIPTPGSLPPLHPSAMHLHLSGVRYPPELSHSSLAALHSERMSSLSAERLQMDEELRREREREREREREADREREKEREREQREKEREKELEREREKERERELERQREQRAREKELLAAKALEPTTFLPVAELHGLRGHSTEERPKPSEQLTPTRAEKLKDVGLQAPKPVQHPLHPVPAPHHTVPSLISSHGIFSLPGSSATTALLIQRTNEEEKWLARQRRLRQEKEDRQSQVSEFRQQVLEQHLDLGRPLVPTEAEHRPESTRPGTNRHEQGSREPPQHFGGPPPLISPKPQQHTVPTALWNPVSLMDNALETRRAESHSLHSHPTAFEPSRQAAVPLVKVERVYCSEKAEEPRKREATPLDKYQPPPPPPPPREAGSLEPQTFPHGPGPFLTELEKSTQTILGQQRPSLSQATSFGELSGPLKPGSPYCHPTARGPDPAYIYDEFLQQRRKLVSKLDLEERRRREAQEKGYYYDLDDSYDESDEEEVRAHLRCVAEQPPLKLDTSSEKLEFLQLFGLTTQQQKEELVAQKRRKRRRMLRERSPSPPAVQCKRQTPSPRLALSTRYSPDEMNNSPNFEEKRKFLTFFNLTHISAEKRKDKERLVEMLRAMKQRALSAADSVTNSSRDSPPVSLSEPATQPAPLETDQPVGVPASLSDVPKTTETGRLEQLRPQELLRVQEPAPPSGEKARLSEAPGGKKSLSMLHYLRGAAPKDIPVPLSHSINGKSKPWEPFVAEEFAHQFHESVLQSTQKALQKHKGNSALLSAEQSHKVDTAIHYNIPELQSSSRVPLPQHNGQQEPPMGRKGPPMQEADQDSEEDSEEDSEEEAEEAPRRQWQGIEAIFEAYQEHIEEQNLERQVLQTQCRRLEAQNYSLSLTAEQLSHSMAELRSQKQKMVSERERLQAELDHLRKCLALPTMHWPRGYFKGYPR
What are the official names of this protein?
Genetic suppressor element 1.
Protein: PACC_GIBFU
Sequence: MSPPAPEQKPQLQQQQQQQGSSSGDSSSGSANDSKSVTPAPSATSNTSQSSTAPSTSSDDNLICRWNACNQKFPAPEALYEHICERHVGRKSTNNLNLTCQWNSCRTTTVKRDHITSHIRVHVPLKPHKCDFCGKSFKRPQDLKKHVKTHADDSVLVRPSQDPQGGLNYRPQPPKGMSHLDSSPRLYYDHTGQMRTNAAAFAHQAGHPSGGYYAPQPSTNYGLYFNQPPINNARTEHLGYSAAAGGYDRKRTYDMVDDFFGSAKRRQIDPSSYAQIGRSLMPLHGNLSVPNGPMTATEQYMPQPAPAPVHAGPTPSQNPLAQQYYLPMPSARTQKDLIHIDTILGQMQDTIYENANHATAGVHIHHAENGFNGYRNTPSPPTSHRSPTGMHVGADGYQPVSAASMASPLTAISSTGTPAVTPPSSSMSYTSGHSPSPSSSAMSPQSRHGSTASVMYPTLPTSLPAVSQGFGHSATTTLGPSFDGSERRRYSGGMLQRARAGPLPLPREDTSGASTPKASESALSVGSPSSESDVSDATREREEQYDRWLENMRVIETLREYVRGRLERKEFVEDNESPRSSHSDAMDVDPKSPQAPPRELGTPREGSSLYPILRMPGA
What is the function of this protein?
Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH.  At alkaline ambient pH, activates transcription of alkaline-expressed genes (including pacC itself) and represses transcription of acid-expressed genes (By similarity).
What are the official names of this protein?
pH-response transcription factor pacC/RIM101.
What is the protein family that this protein belongs to?
Belongs to the pacC/RIM101 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL16_STRSV
Sequence: MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITNRQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKVMFEVAGVSEEIAREALRLASHKLPVKCKFVKREAE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: WDR54_MOUSE
Sequence: MFRRERSIPLRSSAAALSNNLSVLQLPARDLTHFGVVHGPSAQLLSAAPEGVPLAQRQLHVKEGAGVSPPLITQVHWCVLPFRVLLVLTSHRGIQMYESDGSVMVYWHALDSGDASSVQAMFARGIAASVHFICVGTCSGRVLVFDIPAKGPNIVLSEELAGHQTPITDIATERAQGQDGVADMVTADDSGVLCVWRSGPEFTLLTRIPGFGVPCPSVQLWQGIVAAGYGNGQVRLYDASTGALHVQISAHARTISALDLAPEVGKLLSAAEDTFVHIWKLNRNPESGSIEVEHCHGECISDTQVCGARFCDPLGSSFAVTGYDLAEILRFGTV
What is the function of this protein?
When cross-linked to form dimers and trimers, it has a regulatory effect on ERK signaling pathway activity in response to EGF stimulation.  Colocalizes with the EGF receptor in WDR54-specific vesicle where it sustains the internalization and controls the degradation of the EGF receptor after EGF stimulation.
What are the official names of this protein?
WD repeat-containing protein 54.
What are the subcellular locations of this protein?
Vesicle. Note=Aggregates in vesicles when cross-linked.
Protein: PCKG_ACET2
Sequence: MTSTNMTKNKKLLDWVKEMAEMCQPDEIYWCDGSEEENERLIKLMVDSGLATPLNPEKRPGCYLFRSDPSDVARVEDRTFIASKTKEDAGPTNNWIDPVELKATMKELYKGCMKGRTMYVIPFSMGPIGSPISKIGVELTDSPYVVVNMRIMTRIGKAVLDQLGEDGDFVPCLHSVGAPLKEGEKDKGWPCAPIEKKYISHFPEERTIWSYGSGYGGNALLGKKCFALRIASVMARDEGWLAEHMLILRITDPEGNKTYVTGAFPSACGKTNLAMLIPTIPGWKVETIGDDIAWMRFGKDGRLYAINPEAGFFGVAPGTSMDSNPNAMHTIKKNTIFTNVALTDDGDVWWEGIGTEPPAHLIDWQGKDWTPDSGTLAAHPNGRFTAPASQCPVIAPEWEDPEGVPISAILIGGRRPNTIPLVHESFDWNHGVFMGSIMGSEITAAAISNKIGQVRRDPFAMLPFIGYNVNDYLQHWLNMGTKTDPSKLPKIFYVNWFRKDSNGKWLWPGYGENSRVLKWIVERVNGKGKAVKTPIGYMPTVDAIDTTGLDVSKEDMEELLSVNKEQWLQEVESIKEHYKSYGEKLPKELWAQLEALEQRLKEYNG
What is the function of this protein?
Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase [GTP], PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOH_YERPY
Sequence: MKQLYWYTCGEGDCDLVLLHGWGLNSGVWHCIIDRLAPHFRLHLVDLPGYGRSQDYGAMSLADMAERVAQQAPKQALWLGWSMGGLVASQIALSQPECVRGLITVSSSPCFTARDEWPGIKPEVLAGFQHQLSDDFHRTVERFLALQTLGTESSRQDARLLKSVVLQHQMPDVEVLTGGLAILRTADLRTALAGFTLPFMRVYGHLDSLVPRKVASLLDSAWPQTQSVVMQGAAHAPFISHPNDFAKLILNFAEENKK
What is the function of this protein?
The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete.  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.
What are the official names of this protein?
Pimeloyl-[acyl-carrier protein] methyl ester esterase, Biotin synthesis protein BioH, Carboxylesterase BioH.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y561_AGGAN
Sequence: MSLQFNMIALLLVILILLGIFSHNSSITISAAVLLIMQQTLLAKYIPYLEKYGLSIGIVILTIGVLSPLVSGKIQLPGLSAFVSWKMFVAIAVGVFVAWLAGKGVPLMGEQPVLVTGLVIGTIIGVSFLGGIPVGPLIAAGILAVLIGKF
What are the official names of this protein?
UPF0756 membrane protein NT05HA_0561.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DEOC_STRPF
Sequence: MEVKDILKTVDHTLLATTATWPEIQTILDDAMAYETASACIPASYVKKAAEYVSGKLAICTVIGFPNGYSTTAAKVFECEDAIKNGADEIDMVINLTDVKNGDFDTVEEEIRQIKAACQDHILKVIVETCQLTKEELIELCGVVTRSGADFIKTSTGFSTAGATFEDVEVMAKYVGEGVKIKAAGGISSLEDAETFIALGASRLGTSRIIKIVKNEATKTDSY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UXS3_ARATH
Sequence: MAATSEKQNTTKPPPSPSPLRNSKFCQPNMRILISGGAGFIGSHLVDKLMENEKNEVVVADNYFTGSKENLKKWIGHPRFELIRHDVTEPLLIEVDRIYHLACPASPIFYKYNPVKTIKTNVIGTLNMLGLAKRVGARILLTSTSEVYGDPLIHPQPESYWGNVNPIGVRSCYDEGKRVAETLMFDYHRQHGIEIRIARIFNTYGPRMNIDDGRVVSNFIAQALRGEALTVQKPGTQTRSFCYVSDMVDGLIRLMEGNDTGPINIGNPGEFTMVELAETVKELINPSIEIKMVENTPDDPRQRKPDISKAKEVLGWEPKVKLREGLPLMEEDFRLRLNVPRN
What is the function of this protein?
Catalyzes the NAD-dependent decarboxylation of UDP-glucuronic acid to UDP-xylose.  Necessary for the biosynthesis of the core tetrasaccharide in glycosaminoglycan biosynthesis.
What are the official names of this protein?
UDP-glucuronic acid decarboxylase 3, UDP-XYL synthase 3, UDP-glucuronate decarboxylase 3, UGD, UXS-3.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UL32_HHV6Z
Sequence: MYKGWDSEALSIQSEIVNEILLYCYLTPQPPIPSETTTATSPTNIENEISNLESSENLEELKRLSVALNIDRRCNICSIVNLCLKQNKSWIYDYSLLCYKCNYAPKTPLSLLIVSAEFIMLIRERFPNINFDGLFQNNIVSIFDFHVHFFIHRCFANTVNDHIQSENITLNHMAIIRSTLLKEDSIPHIKIKKFLTKKMNPKKTQSPELNKKLTVPMKTRFTTLLFYMWSGTNVFDRVPFTDLTIRKHRFIKNLYSNKTDIELTAGPILLAQIPFSITKNKTTSVCLLCELMAASKQDYLFLKYLHQSIMDYCQNNLKMIDRVQFVIADIFEKTKIHMHVKNLSDYSKAIFDNEFSFSDDNFTLDTHVYLILRQTGTVGVYKHFFCDPLCLANCKTINPEVLFNTTDAGEIQDLKVTICYRNEYLSIVEKHVWLAIHLFKAFQIIKPNHKNKTQIAEFLKDFTNLLALHHFDIVDPIFTVNYYV
What is the function of this protein?
Plays a role in efficient localization of neo-synthesized capsids to nuclear replication compartments, thereby controlling cleavage and packaging of virus genomic DNA.
What are the official names of this protein?
Packaging protein UL32 homolog.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae UL32 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=Mainly cytoplasmic in transfected cell culture.
Protein: MED8_ASPCL
Sequence: MASPSQDQIKVLEQSRQRLVQLTRSLGSLIGSLNQSDPLPSWSSLQSQASIISNNLLSVSEHLSDNCDLLSALVAYPGPEYPGRTQASTLEQLLRTKLDPRIEDWVARGRRAGASALEDKDALSETELAELWDWAPVEANQEARRRNWGGDYTLEEREMGIQNVVTGLRRQLEDDERDEDEDEDDEEEEEGEGEDEEMEVVGVRRRSDAGAGLGFDTAVPTPASSQQVQKGAGPVVPLDDVLRFMTTGTLPQQR
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 8, Mediator complex subunit 8.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 8 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: T23O_BACAH
Sequence: MKENEKVIMEKGIHTDFKENMTYGEYLQLDSLLSSQKRLSDHHDEMLFIVIHQASELWMKLILHELNAAIESIKQDKLQPAFKMLARVSKIQSQIIQSWDILATLTPSEYIEFRDSLGQASGFQSYQYRMIEYALGYKTPHALKIYEKDPELHARLHTALHAPSLYDVAIQALVKEGFPIHKDVLNRDITQPYEEDATVEAAWLEVYADVKKYWNLYQLAEKLIDIEDWLQQWRFRHMKTVERIIGHKMGTGGSSGVSYLKRVLDQRFFPELWNVRTKL
What is the function of this protein?
Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine.  Catalyzes the oxidative cleavage of the indole moiety.
What are the official names of this protein?
Tryptophan 2,3-dioxygenase, TDO, Tryptamin 2,3-dioxygenase, Tryptophan oxygenase, TO, TRPO, Tryptophan pyrrolase, Tryptophanase.
What is the protein family that this protein belongs to?
Belongs to the tryptophan 2,3-dioxygenase family.
Protein: RPOC2_ORYNI
Sequence: MAERANLVFQNKEIDGTAMKRLISRLIDHFGMGYTSHILDQIKTLGFHQATTTSISLGIEDLLTIPSKGWLVQDAEQQSFLLEKHYYYGAVHAVEKLRQSVEIWYATSEYLKHEMNSNFRITDPSNPVYLMSFSGARGNASQVHQLVGMRGLMADPQGQMIDLPIQSNLREGLSLTEYIISCYGARKGVVDTAVRTADAGYLTRRLVEVVQHIIVRRRDCGTIQAISVSPQNGMTEKLFVQTLIGRVLANDIYIGSRCIATRNQDIGIGLVNRFITTFRAQPFRAQPIYIRTPFTCRSTSWICQLCYGRSSTHGDLVELGEAVGVIAGQSIGEPGTQLTLRTFHTGGVFTGGTADLVRSPSNGKIQFNGDLVHPTRTRHGQPAFLCYIDLHITIQSQDILHSVTIPSKSLILVQNDQYVESEQVIAEIRAGTSALHFKEKVQKHIYSESDGEMHWSTDVYHAPEYQYGNLRRLPKTSHLWILSVSMCRSSIASFSLHKDQDQMNTYSFSVDGRYIFGLSMADDEVRHRLLDTFGKKDREILDYSTPDRIMSNGHWNFVYPSILQNNFDLLAKKRRNRFAIPLQYHQEQEKEPISCFGISIEIPFMGVLRRNTIVAYFDDPRYKKDKKGSGIVKFRYRTLEDEYRTREKDSENEYGSPENEYRTREEECKTLEDEYRTREEEYETLEDEYGIPENEYETLEDEYGILEDEYRTREEESEDEYGSPENKYRPREDKYGTLEEDSEDEHGTLEEDSEEDSEDEYGNPEEDSVLKKGVLIEHRGTKEFSLKYQKEVDRFFFILQELHILPRSSSLKVLDNSIIGVDTQLTKNTRSRLGGLVRVKRKKSHTELKIFSGDIHFPEEADKILGGSLIPLEREKKDSKESKKRENWVYVQWKKILKSKEKYFVLVRPAVAYEMNEGRNLATLFPQDLLQEEGNLQLRLVNFISHENSKLTQRIYHTNSQFVRTCLVLNWEQEEKEEARASLVEIRANGLIRDFLRIGLIKSTISYTRKRYDSRSAGLILHNRLDRTNTNSFYSKAKIQSLSQHQEAIGTLLNRNKEYQSLMVLSASNCSRIGFFKNSKNPNGVKESNPRIPIPKFFGLFRNFSGLLGTIAPSISNFSSSYYLLTYNQILLKKHLLLDNLKQNFKVLQGLKHSLINENQRTSNFDSNIMLDPFQLNWHFLPHDSWEETSAKIHLGQFICENVCLFKSHIKKSGQIFIVNIDSFVIRAAKPYLATTGATVHGHYGEILYKGDRLVTFIYEKARSSDITQGLPKVEQIFEARSIDSLSPNLERRIEDWNERIPRILGGPWGFLIGAELTIAQSRISLVNKIQKVYRSQGVQIHNRHIEIIIRQVTSKVRVSEDGMSNVFSPGELIGLLRAERAGRALDESIYYRAILLGITRVSLNTQSFISEASFQETARVLAKAALRGRIDWLKGLKENVVLGGIIPVGTGFQKFVHRYPQDKNLYFEIQKKKLFASEMRDILFLHTELVSSDSDVTNNFYETSESPFTPFI
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta'', PEP, Plastid-encoded RNA polymerase subunit beta'', RNA polymerase subunit beta''.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TRUA_CHLPN
Sequence: MTKVALLIAYQGTAYSGWQQQPNDLSIQEVIESSLKKITKTRTPLIASGRTDAGVHAYGQVAHFRAPDHPLFANANLTKKALNAILPKDIVIRDVALFDDNFHARYLTIAKEYRYSLSRLAKPLPWQRHFCYTPRHPFSTELMQEGANLLIGTHDFASFANHGRDYNSTVRTIYTLDIVDKGDSLSIICRGNGFLYKMVRNLVGALLDVGKGAYPPEHLLDILEQKNRREGPSAAPAYGLSLHHVCYSSPYNNFCCEQCSVSTSNEG
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: RIMC1_MOUSE
Sequence: MAAAVSGVVRRVEELGDLAQAHIQHLSEAAGEDDHFLIRASAALEKLKLLCGEEKECSNPSNLLELYTQAILDMTYFEENKLVDEDFPEDCSPQKVKELLAFLSEPEILAKESNMHPKLCGLLGAELLECLSWRRGALLYMYCHSLTKRREWLLRKSNLLQKYLVDGINYLLQMLNYRCPVQLNEGVSFQDLDTAKLLSTGVFSDIHVLAMMYSGEMCYWGLKHCTDQQSENHEVDTDVFGASCTTHKETLDFREVGEKILKKYVSVCEGPLKEQEWNTANAKQILSFFQQRCS
What is the function of this protein?
Plays an important role in the removal of damaged mitochondria via mitophagy by controlling the stability and localization of RAB7A (By similarity).  Required for the recruitment of RAB7A and ATG9A vesicles to damaged mitochondria and promotes the stability of RAB7A by inhibiting its proteasomal degradation during mitophagy (By similarity).
What are the official names of this protein?
RAB7A-interacting MON1-CCZ1 complex subunit 1, UPF0600 protein C5orf51 homolog.
What is the protein family that this protein belongs to?
Belongs to the RIMOC1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: Y1085_YERPN
Sequence: MKTKLNELLEFPCSFTYKVMGIAEPQLVDQVVEVVQRHAPGEYTPQVKPSSKGNYHSVSITITATHIDQVETLYEELGNLELVKMVL
What are the official names of this protein?
UPF0250 protein YPN_1085.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.
Protein: LRGB_STAA1
Sequence: MINHLALNTPYFGILLSVIPFFLATILFEKTNRFFLFAPLFVSMVFGVAFLYLTGIPYKTYKIGGDIIYFFLEPATICFAIPLYKKREVLVKHWHRIIGGIGIGTVVALLIILTFAKLAQFANDVILSMLPQAATTAIALPVSAGIGGIKELTSLAVILNGVIIYALGNKFLKLFRITNPIARGLALGTSGHTLGVAPAKELGPVEESMASIALVLVGVVVVAVVPVFVAIFF
What is the function of this protein?
Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and/or CidB.  The LrgAB and CidAB proteins may affect the proton motive force of the membrane.  May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses.
What are the official names of this protein?
Antiholin-like protein LrgB.
What is the protein family that this protein belongs to?
Belongs to the CidB/LrgB family. LrgB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYK_LYSSC
Sequence: MKQVSNIEELNDQLLVRRQKMTTILENGQDPFGSRFERTHLSTEVKEQFADQTKEQLEENLQEVIIAGRIMTKRGKGKAGFAHIQDLGGQIQIYVRQDHVGEEAYELFKQADLGDIVGIRGNVFRTQVGELSVKAEEFTFLTKALRPMPEKFHGLQDVEQRYRQRYLDLMTNEDSKLTFIARSKIIRAIRNYLDNAGYLEVETPMLHTIAGGAAARPFITHHNALDMELYMRIAIELHLKRLIVGGLEKVYEIGRVFRNEGISTRHNPEFTMIELYEAYADYQDIMSLTENLIAHVAQEVLGTTTVQYGEDEINLAVGWKRVHMVDAVKEATGVDFWQPMTKEQAQALAKEHGVEVKDVHEVGHIINEFFEQKIEETLVQPTFVYGHPVEISPLAKKNPEDERFTDRFELFIVRREHANAFTELNDPIDQRQRFEAQLAEKAAGNDEAHEMDNDFIEALEYGMPPTGGLGIGIDRLIMLLTNSPSIRDVLLFPTMRHITK
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_STRGC
Sequence: MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: GET1_ASPFU
Sequence: MLSLILTIFFVHVAIYLVNTVGATTIDTLLWILYLKLPTSTSRNARQQSRLKREVVQLKREMNNTSSQDEFAKWAKLRRKHDKAMDEYEAMNKKLTAQKTSFDWSVKIARWLSTNGLKIFLQFYYSKTPVFALPAGWFPFYVEWVLSFPRAPRGSVSVQVWNSVCATAIAVMAEIVTSMLLQLRSRSASPASTAKAQKAQ
What is the function of this protein?
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Acts as a membrane receptor for soluble get3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.
What are the official names of this protein?
Protein get1, Guided entry of tail-anchored proteins 1.
What is the protein family that this protein belongs to?
Belongs to the WRB/GET1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: YWDE_BACSU
Sequence: MRISSCLYGFVAHGAVFLFTGGCMLLAMAASLPFVFLLDRLPDVVFTAGAILTLLCSYAYVWFWAVRFAYNQKMRLFEVQLGSFVLLALMISLFLLDGSSMKDIMMNWDDAGCAFVPPAFTFLCLSYALVLLPVYQSKLWRLILPNGVRMKDIFHVFGDLMLIMVLLIGATLLFLSL
What are the official names of this protein?
Uncharacterized protein YwdE.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ERA_VIBVU
Sequence: MADNEFDIDAFFSTEKKSTSSENQHCGFIAIVGRPNVGKSTLLNKILGQKISITSRKPQTTRHRIMGVDTDGDYQAIYVDTPGLHIEEKRAINRLMNRAANSSLSDVNLVFFLVDGTHWTNDDEMVLNKLQKANFPVVLCVNKVDNVQDRNEVMQHMMEMSKKMNFVDVVPISAKQGKNIDVLRKHVRDHLPKAVHHFPEEYVTDRSQRFMASEIVREKLMRFTGDELPYSVTVEIERFDYNPETDGFHINALILVERSGQKKMVIGKGGEKIKTIGREARLDMEELFGRKVYLETWVKVKSGWADDERALRSLGYIDDL
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: DC1I2_MOUSE
Sequence: MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKETDQKKEAAVSVQEESDLEKKRREAEALLQSMGLTTDSPIVPPPMSPSSKSVSTPSEAGSQDSGDGAVGSRRGPIKLGMAKITQVDFPPREIVTYTKETQTPVTAQPKEDEEEEDDVATPKPPVEPEEEKTLKKDEENDSKAPPHELTEEEKQQILHSEEFLSFFDHSTRIVERALSEQINIFFDYSGRDLEDKEGEIQAGAKLSLNRQFFDERWSKHRVVSCLDWSSQYPELLVASYNNNEEAPHEPDGVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPNLVVGGTYSGQIVLWDNRSNKRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLISISTDGKICSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNSDYVYDVMWSPTHPALFACVDGMGRLDLWNLNNDTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIYDVGEQIAVPRNDEWARFGRTLAEINANRADAEEEAATRIPA
What is the function of this protein?
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function (By similarity).  Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules (By similarity).  The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCTN1 (PubMed:27474409).  Involved in membrane-transport, such as Golgi apparatus, late endosomes and lysosomes (PubMed:27474409).
What are the official names of this protein?
Cytoplasmic dynein 1 intermediate chain 2, Cytoplasmic dynein intermediate chain 2, Dynein intermediate chain 2, cytosolic, DH IC-2.
What is the protein family that this protein belongs to?
Belongs to the dynein intermediate chain family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm. Note=Detected in the cytoplasm of pachytene spermatocytes. Localizes to the manchette in elongating spermatids.
Protein: RL3_MAGSA
Sequence: MRSGLIAQKVGMTRIFTEDGTHVPVTVLKVDTCQVVSTRSVEKDGYVAVQLGAGTAKVKNVSKPARANFAKAKVEPKKKLVEFRVAPENLLEVGTELSAAHFIPGQYVDVTGTTIGKGFAGGMKRWNFRGLEATHGVSVSHRSHGSTGQRQDPGKVFKGKKMAGHMGDEQVTTQNLTVVSTDADRGLILVKGSVPGHEGSWVLVRDAVKRKLPDGVPFPAGVKAAASAE
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: CEF1_YARLI
Sequence: MAYVKGGVWTNVEDEILRAAISKYGLNQWARVSSLLARKTAKQCKARWTEWLDPTIKKIEWSREEDEKLLHLAKIFPAQWRTIAPFVGRTAHQCIQRYERLLAEVAGEVEGEDASAVASAPATEGDQFPETKPARPDAVDMDEDEKEMLSEARARLANTQGKKAKRKDRERMLEDSRRLSQLQKRRELKNAGIDTRLSKRKKNEMDYNADIPFEHKPARGFYSTAEEEHENDSERLQHKQMHRTAADAPGPSQKRDKATLSKEDEEKKKEQQKTASAQRTLQLAQLDLQDQISKRRKLNLPEPQIQDQEMEEIVKLGAQGEALHKRYADGVASSLSGDYDDKIVDDSIRTPQIQQSKVKTTIEEIKAMENRSVLGKRTEEEVDDEAEADKDGFAIPKLPSNKAVTSVSAGSDIGGATPAGMTPIKRDALGLVGSVEATPVSILRQKLASLPKPKNDFEITAEDEEEDEEADKEKKPTDNLPVDKGEQARLKRIAEEQERQEALKTRSQTLQRGLPRATVPEVTYNDAIGQEVVALLREEELRFPNKGDSVALMQSEFSLDDLVDAETLIEMELMEGDEQEVQEEGIKTAALPGTVARSDESEEEFKTRVEIISDQLVETLTSLAETCQTEETALVDKFKAYAKRQATLSKKLTSRWSQLESVEVEIAVFSELARMEEIAIEQRSAALQEEVDWLVKKERAAQDKYRELKVKEQAAKGGH
What is the function of this protein?
Involved in pre-mRNA splicing and cell cycle control.
What are the official names of this protein?
Pre-mRNA-splicing factor CEF1.
What is the protein family that this protein belongs to?
Belongs to the CEF1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: YCF46_TRICV
Sequence: MKFNDELILLLKARYPIIYINTIEEDRVEYIIRKHIKANLNRSIYSWDFVDGYTNNPNNEGFAKRNPLQALELIERLTSETPALFLLKDFNRFLTDISISRKLKNVSRILKLQPKTIIIIGSDFQIPKELQDLITVLQFNLPVENEITQELTRLVNSLNLTIDPSLFESLTRACQGLSLERIRRVLSKIIATHKTIDENSISILLSEKKQIISQTEILEYWSVNEKMGNIGGVDNLKDWLKKRKTSFTIQASNYGLPTPRGLLLIGIQGTGKSLTAKAIATEWQLPLLKLDVGRLFGGIVGESESRLRQMIDVAETLSPCILWIDEMDKAFSNNDSRGDSGTSNRVLATFISWLSEKTKPVFVVATANNVDLLPLEIIRKGRFDEIFFLDLPELEERKEIFKIHIQEFRPNSWKLFDYKKLAQLSESFSGAEIRQSIIEAMYQAFDQQREFTTDDICLALKQLIPLAQLENSQTLKLQSWASSGRIRLASSKRISIN
What are the official names of this protein?
Uncharacterized AAA domain-containing protein ycf46.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. Highly divergent.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: AHPD_RHIWR
Sequence: MSLKEFADALPDYAKDIRLNVGSLLGDQTLTEQRKYGLLLACAHGSGYKPIVEATEAEVAGKLSPEAANAARAAAAVMAMNNVYYRFVHLASNKEYGQMPAKLRMNVIGSPGIEKDDFELFSLAVSAMNGCGLCIDSHEKVLRQHGVAADVIQTAARVGAVIKAAATVHATAV
What is the function of this protein?
Antioxidant protein with alkyl hydroperoxidase activity.  Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
What are the official names of this protein?
Alkyl hydroperoxide reductase AhpD, Alkylhydroperoxidase AhpD.
What is the protein family that this protein belongs to?
Belongs to the AhpD family.