PharMolix/UniProtQA huggingface dataset:
Protein: GB_SUHVF
Sequence: MPAGGGLWRGPRGHRPGHHGGAGLGRLWPAPHHAAAARGAVALALLLLALAAAPPCGAAAVTRAASASPTPGTGATPNDVSAEASLEEIEAFSPGPSEAPDGEYGDLDARTAVRAAATERDRFYVCPPPSGSTVVRLEPEQACPEYSQGRNFTEGIAVLFKENIAPHKFKAHIYYKNVIVTTVWSGSTYAAITNRFTDRVPVPVQEITDVIDRRGKCVSKAEYVRNNHKVTAFDRDENPVEVDLRPSRLNALGTRGWHTTNDTYTKIGAAGFYHTGTSVNCIVEEVEARSVYPYDSFALSTGDIVYMSPFYGLREGAHGEHIGYAPGRFQQVEHYYPIDLDSRLRASESVTRNFLRTPHFTVAWDWAPKTRRVCSLAKWREAEEMTRDETRDGSFRFTSRALGASFVSDVTQLDLQRVHLGDCVLREASEAIDAIYRRRYNSTHVLAGDRPEVYLARGGFVVAFRPLISNELAQLYARELERLGLAGVVGPAAPAAARRARRSPGPAGTPEPPAVNGTGHLRITTGSAEFARLQFTYDHIQAHVNDMLGRIAAAWCELQNKDRTLWSEMSRLNPSAVATAALGQRVSARMLGDVMAISRCVEVRGGVYVQNSMRVPGERGTCYSRPLVTFEHNGTGVIEGQLGDDNELLISRDLIEPCTGNHRRYFKLGSGYVYYEDYNYVRMVEVPETISTRVTLNLTLLEDREFLPLEVYTREELADTGLLDYSEIQRRNQLHALKFYDIDRVVKVDHNVVLLRGIANFFQGLGDVGAAVGKVVLGATGAVISAVGGMVSFLSNPFGALAIGLLVLAGLVAAFLAYRHISRLRRNPMKALYPVTTKTLKEDGVDEGDVDEAKLDQARDMIRYMSIVSALEQQEHKARKKNSGPALLASRVGAMATRRRHYQRLESEDPDAL
What is the function of this protein?
Envelope glycoprotein that forms spikes at the surface of virion envelope.  Essential for the initial attachment to heparan sulfate moieties of the host cell surface proteoglycans.  Involved in fusion of viral and cellular membranes leading to virus entry into the host cell.  Following initial binding to its host receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.  May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress.
What are the official names of this protein?
Envelope glycoprotein B, gB.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein B family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN).
Protein: LEUD_BIFLD
Sequence: MEKLTTLTGVGVPLRRSNVDTDQIIPAVFLKRVTKSGFDDALFYAWRRDPNFVLNKPEYAGKGQILVAGPEFGIGSSREHAVWALHDYGFRVVIAPSFADIFYGNTAKNGVLAAIMPQESVELLWKLLEEEPGREMTVSLETRTVTCGDVTLPFEVNDYVRWRLMNGYDDIDLTLQHEDDIAAYEKMRAEKFPFKPKTIPAKHWAEERIESAREPEDADWTGPLADRGII
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: TEG5_VZVD
Sequence: MQSGHYNRRQSRRQRISSNTTDSPRHTHGTRYRSTNWYTHPPQILSNSETLVAVQELLNSEMDQDSSSDASDDFPGYALHHSTYNGSEQNTSTSRHENRIFKLTEREANEEININTDAIDDEGEAEEGEAEEDAIDDEGEAEEGEAEEDAIDDEGEAEEGEAEEDAIDDEGEAEEGEAEEGEAEEGEAEEDAIDDEGEAEEDAAEEDAIDDEGEAEEDYFSVSQVCSRDADEVYFTLDPEISYSTDLRIAKVMEPAVSKELNVSKRCVEPVTLTGSMLAHNGFDESWFAMRECTRREYITVQGLYDPIHLRYQFDTSRMTPPQILRTIPALPNMTLGELLLIFPIEFMAQPISIERILVEDVFLDRRASSKTHKYGPRWNSVYALPYNAGKMYVQHIPGFYDVSLRAVGQGTAIWHHMILSTAACAISNRISHGDGLGFLLDAAIRISANCIFLGRNDNFGVGDPCWLEDHLAGLPREAVPDVLQVTQLVLPNRGPTVAIMRGFFGALAYWPELRIAISEPSTSLVRYATGHMELAEWFLFSRTHSLKPQFTPTEREMLASFFTLYVTLGGGMLNWICRATAMYLAAPYHSRSAYIAVCESLPYYYIPVNSDLLCDLEVLLLGEVDLPTVCESYATIAHELTGYEAVRTAATNFMIEFADCYKESETDLMVSAYLGAVLLLQRVLGHANLLLLLLSGAALYGGCSIYIPRGILDAYNTLMLAASPLYAHQTLTSFWKDRDDAMQTLGIRPTTDVLPKEQDRIVQASPIEMNFRFVGLETIYPREQPIPSVDLAENLMQYRNEILGLDWKSVAMHLLRKY
What is the function of this protein?
Tegument protein that can bind to various RNA transcripts.  Plays a role in the attenuation of selective viral and cellular mRNA degradation by modulating the activity of host shutoff RNase ORF17/VHS.  Also plays a role in the primary envelopement of virions in the perinuclear space, probably by interacting with two nuclear egress proteins ORF24 and ORF27.
What are the official names of this protein?
Tegument protein UL47 homolog.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae HHV-1 UL47 family.
What are the subcellular locations of this protein?
Virion tegument. Host nucleus. Host cytoplasm. Note=Major tegument protein of the virion. Undergoes nucleocytoplasmic shuttling during infection. Localizes to the major sites of transcription in the infected cell nucleus.
Protein: Y911_SYNJA
Sequence: MDDQATRPTAATSPVLVIAGLTGSGKTLAIQQLEQLGYTGLEGIPPDQAVYLIEAIRPRHPALAVSLNLHTPEYREQFLAFDRWRQAQGIPFLFLEARPLVLLNRLSAHRRPHPHRPGLGLLEAIEQEVRDLAPVRERCTHLLDTSELNSQQLRQQLQALVHGIPQPLNLRLVSFGFKYGAPPDANLLFDVRFLPNPFFQPHLRHLTGQDPPLQEFLFADPVTQSTYRQIFSLVQAFWPHYRAERRPHLTVAIGCTGGQHRSVALVERLAEDLRPWAVPTDNPALPALNIQVQHRHLLDSQRELEARFGPPPPAAGVEQQQVRIPLAGVPAPPHD
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein CYA_0911.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: RS17_LISMF
Sequence: MADRNQRKVYTGRVVSDKMDKTITVVVETYKKHGLYGKRVKYSKKFKAHDENNIAKTGDVVRISETRPLSATKHFRLLEVVEEAVII
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: TRPF_METAC
Sequence: MKTRPKTRIKTRVKICGIRSPKDIEFAALYGADAVGFITEVPVESPRKLDSDTAAALISKVPKCLDSVMVIMPETSTSALELIEKVKPNIVQIHSDLPLSELKAVREKADIPIIKTLSVPAEQEAPKLHNIVTRLLEEVRELEESGIVDSVLLDSGIAGKTGGTGCVHDWDLSRRIAEETELPLILAGGLKPENVQEAIRSVSPYAVDTASGVETQGKKDSVKVRKFIEEVRCTYAFL
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: G6PI_PSEPF
Sequence: MAYYRTPHDVTALPAWQALKDHRQAMQDFSMREAFNADPQRFNQFTLSSCGLFLDYSKNLINAETRNLLVGLANEVDLKGAIKALFDGEIVNSSEGRPALHTALRRPVGDKLSVNGVNVMPEVHKVLNQITDLVGRIHDGLWRGYTEKPITDVVNIGIGGSFLGPELVSEALLSYAQKGVRCHYLANIDGSEFHELTQKLRAETTLFIVSSKSFNTLETLKNAQAARAWYLAQGGSEAELYRHFIAVSSNNAAAVAFGIREENIFPMWDWVGGRYSLWSAIGLPIALAIGMSNFKELLSGAYTMDQHFQSAPFEQNMPVLLALLGVWYGNFWGAQSHAILPYDHYLRNITKHLQQLDMESNGKSVRQDGTPVSTDTGPVIWGGVGCNGQHAYHQLLHQGTQLIPADFIVPIVSFNPVSDHHQWLYANCLSQSQALMLGKTLPEAEAELRDKGMSEDQVQKLAPHKVIPGNRPSNTLVVERISPRRLGALVAMYEHKVFVQSVVWGINAFDQWGVELGKELGKGVYNRLVGSEETAAEDASTQGLINYFRGRHRG
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_SHEAM
Sequence: MSGNSIGQNFVVTTFGESHGVALGCIIDGCPPGLELTEADMQHDLDRRRPGTSRYTTARREPDEVRILSGVFEGKTTGTSIGLIIENTDQRSQDYSNIKDLFRPGHADYTYQQKYGLRDYRGGGRSSARETAMRVAAGAVAKKYLKAVHGIEIYGFLSQLGPIEAEHIDREQIEQNAFFFPDASKLEALDEYMRELKKSGDSIGAKVSVIATNVPVGLGEPVFDRLDADIAHALMGINAVKGVEIGDGFAVVTQKGSEHRDLMSPEGFASNHAGGVLGGISSGQPIVAHMALKPTSSISIPGESMTVQGNTAEVVTKGRHDPCVGIRAVPIAEAMLAIVLMDHLLRHRAQNQHVHSETPVLGMRS
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: ISPE_BACC0
Sequence: MKLLVKAPAKINLSLDVLGKRQDGYHEVKMIMTTIDLADRLELMELAEDRIEILSHNRYVPDDQRNLAYQAAKLLKEKFNVKKGVSITIEKTIPVAAGLAGGSSDAAATLRGLNKLWNLGLTIDQLAELGAEIGSDVSFCVYGGTAIATGRGEQIEHIKTPPSCWVILAKPHIGVSTADVYGNLKLNRVTHPNVDKMVDVINAGDYKGICDTVGNVLEDVTFAMHPEVARIKAQMKRFGADAVLMSGSGPTVFGLVHHDSRMHRIYNGLKGFCEQVYAVRLLGERETLE
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: YQGF_FRATH
Sequence: MFQSLIAIDYGKARIGIASGQMITKTATPIGTVEAYDGVPNWIELDKIIKRWNPSDIIIGLPLDTQNFETDITKSAKDFAKEVQQRYQRKVHLINEAYSTREARWRLEEVKSKKVSHIKVDALAACVILETWMSEN
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSB_YERP3
Sequence: MSGWRKIYYKLLNLPLKLLVKSKVIPADPVSELGLDPSRPILYVLPYNSKADLLTLRAQCLAQDLPDPLIPLEIDGVQLPSHVFIENGPRVFRYYVPKQESVKLFHDYLDLHRNNPALDIQMLPVSVMFGRSPGREGHGTPHLRVLNGVQKFFAVLWLGRDSFVRFSTTVSLRRMASEHGTDKTIAHKLARVARMHFSRQRLAAVGPSLPARQDLFKKLLASKAIEKAVADEARSKKISHEKAQQNAITLMEEIAANFSYEAVRLSDRVLSWTWNRLYQGINVHNAERVRQLAQDGHEIVYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFTRGYSVEYFVEGGRSRTGRLLEPKTGTLSMTIQAMLRGGTRPITLVPIYIGYEHVMEVGTYAKELRGAIKEKENLLQMLRGLRKLRNLGQGYVNFGEPLPLTTYLNTHVPQWRDAIDPIEAQRPSWLTPAVNDLANQIMVRINNAAAANAMNLCSTALLASRQRSLTREQLLEQLDCYLQLMRNAPYAKDTTVPDKTPEELLNHALNMNKFEVEKDTIGDIIILPREQAVLMTYYRNNIQHLLILPSLIASMVMYHRRITRTELLHKISMIYPMLKAELFLHYSKEQLPETLDTLIDELARQQLICDKGSELVLNPARIRPLQLLAAGVRETLQRYAITLSLLSATPSINRGALEKESRIMAQRLSVLHGINAPEFFDKAVFSTLVATLREEGYISDSGDAIQEHTLEVYNMLSALMTPEVKLTIESVSMPAETSNQPEAPETPEPEGKTES
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, GPAT.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PXPA_ALKCK
Sequence: MNAIDLNSDVGESYGAYTIGNDEKIMPYISSANIACGFHAGDAHVMRETVARALEHSVAIGAHPGLPDIGGFGRRNIDISPQEGYELVVYQIGALWAIAKAQGGKLHHVKPHGALYNMAAADQALAEAIANAVYDVDPNLVFYGLAGSALIAAGKKAGLKTASEVFADRTYQADGSLTSRRAPNALITDAKEASAQVLRMIQEGKVRTQQGTDVKIDAQTVCIHGDGAQAVAFAEQLKGELERHGITVKAGNC
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: ERIT1_HUMAN
Sequence: MLACFPCFLRRKMPCLLKVADAGCSVGLGKVHCSCHLPNPRVLRHCDILTGVLTLGLDMSCHACLSAGTGLGEELVGLGPGSTCLVKHLWLLFPCHRLASQNYSDSLAQQWSFSLLIMWLCNREREIFMSKCAKCI
What are the official names of this protein?
Putative uncharacterized protein encoded by ERC2-IT1, ERC2 intronic transcript protein 1, PO42.
Protein: ISCS_ECO5E
Sequence: MKLPIYLDYSATTPVDPRVAEKMMQFMTMDGTFGNPASRSHRFGWQAEEAVDIARNQIADLVGADPREIVFTSGATESDNLAIKGAANFYQKKGKHIITSKTEHKAVLDTCRQLEREGFEVTYLAPQRNGIIDLKELEAAMRDDTILVSIMHVNNEIGVVQDIAAIGEMCRARGIIYHVDATQSVGKLPIDLSQLKVDLMSFSGHKIYGPKGIGALYVRRKPRVRIEAQMHGGGHERGMRSGTLPVHQIVGMGEAYRIAKEEMATEMERLRGLRNRLWNGIKDIEEVYLNGDLEHGAPNILNVSFNYVEGESLIMALKDLAVSSGSACTSASLEPSYVLRALGLNDELAHSSIRFSLGRFTTEEEIDYTIELVRKSIGRLRDLSPLWEMYKQGVDLNSIEWAHH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur and selenium atoms from cysteine and selenocysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.  Also functions as a selenium delivery protein in the pathway for the biosynthesis of selenophosphate.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BGL1_PASFU
Sequence: LVAHEENVRVGKDEGFAKAGGLSRLPLEAGESGTATFNVR
What are the official names of this protein?
Beta-glucosidase 1, Beta-D-glucoside glucohydrolase, Cellobiase, Gentiobiase.
Protein: CCD68_MOUSE
Sequence: MTTVTVTTEVPSSGKTEDGHVFCDSSSAHIIEETEYVRQMRTTLEKIRNHMFKEKEGCGNARHKLDAEGSGNIQNGSDSTTDPTCLDLLMENMRRKDQQLLEMNRENEVLQIKLEASREAGAAALRNVAQRLFDNYQTQAGDLEKKHEGRKHLLQVNNLEKEQALKGSAESLNLLSEKLEEKHGQIVGLENRVQRMENEKKTLLEKKLRLESKLFQLKSNAANPKSCQDLQTEISILQEQISHLQFVIHSQHQNLRSIIQEMEGLKNTLKEQDTKIENLKEKVTVLEAQNKELKTRVAHWTETPRTLVSKAVSTSELKTEGASPYLMLIRLRK
What is the function of this protein?
Centriolar protein required for centriole subdistal appendage assembly and microtubule anchoring in interphase cells (PubMed:28422092).  Together with CCDC120, cooperate with subdistal appendage components ODF2, NIN and CEP170 for hierarchical subdistal appendage assembly (PubMed:28422092).
What are the official names of this protein?
Coiled-coil domain-containing protein 68.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localizes to the subdistal appendages of centrioles.
Protein: RS17_BACAA
Sequence: MSERNQRKVYTGRVVSDKMDKTITVLVETYKTHSLYGKRVKYSKKYKAHDEQNQAKLGDIVKIMETRPLSATKRFRLVEIVEEAVII
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: CFA52_PIG
Sequence: MENQIQPKAEVAKLELEAVIGFNGHVPTGLKCHPDQEHLIYPLGCTILIQAIKTQEQNFLHGHSNNVSCVTISKSGVYIASGQVTFMGFKADIILWDYKKRELMARLSLHKGKIEALAFSPNDLYLVSLGGPDDGSVVVWSIAKTEAICGSPAAGLNVGNATSVVFSQCHDEMFVTAGNGTIRVWELDLPNRKIWPTECQTGQMKRIVMSISMASDDSFFYLGTTTGDILKMNPRTKLLADTGPAKDKFSLGVSAIKCLKTGGLLVGSGAGLLVFCRSPSYKPIKKIQLQGGITSISLRGEGHQFFVGTEESHIYRVNFTDFKETLVTTCHFEAVEDVVFPFGTAELFATCAKKDIRVWHTLSNRELLRITVPNMTCHGIDFMRDGKSLISAWDDGKIRAFAPETGRLMYVISNAHRIGVTAVATTSDCTRVISGGGEGEVRVWQIGHQTQKLEEALKEHKSSVSCIRVKKNNEECVTASTDGTCIIWDLVRLRRNQMILANTLFQCVCYHPEEFQIITSGTDRKIAYWEVFDGSGIRELDGSLSGSINGMDITPEGVHFVTGGNDHLVKVWDYNEGEVTHVGVGHSGNITRVRISPGNEYIVSVSADGAILRWKYPFPS
What is the function of this protein?
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating (By similarity).  Important for proper ciliary and flagellar beating.  May act in cooperation with CFAP45 and axonemal dynein subunit DNAH11 (PubMed:33139725).  May play a role in cell growth and/or survival (By similarity).
What are the official names of this protein?
Cilia- and flagella-associated protein 52, WD repeat-containing protein 16.
What is the protein family that this protein belongs to?
Belongs to the CFAP52 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, cilium, flagellum. Cytoplasm, cytoskeleton, cilium axoneme. Note=Located in the proximal region of respiratory cilia.
Protein: GSA_DESHD
Sequence: MGFQDQRSKEAFARANGVLPGGVNSPVRAFKSVGREPIFIAKGQGARLWDIDGNSYLDYVLSWGPLILGHAHPVVVGAIKAAAERGTSYGAPTEIETECAEEVIKAFPSMEMVRMVSSGTEATMSALRLARGVTGRNKIIKFEGCYHGHGDSLLIKAGSGALTFGVPTSPGVPSSVASQTIVAQYNDLEGLKEIFKECGEDIAAVILEPVTGNMGVVLPQPGFLAGLRTLTQDYGSLLIFDEVMTGFRVSYGGAQGRYQIDPDLTCLGKVIGGGLPVAAYGGKRKYMEQVAPSGPIYQAGTLSGNPLAMAAGLATLKLLQQEGVYEGLEKKTARLAEGLQSIAQELGFPIWVNSVGAMFSAFFTDQPVIDFKSACSSDVERFGSFFRGMLERGIYLAPSQYEAVFLSAAHTDADIDYTLEQARDVLKSLG
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHAS_ENT38
Sequence: MTVLHSVDFFPSGHSPVAIEPRLPQAAFPEHHHDFHEIVIVEHGTGIHVFNGQPYTISGGTVCFVRDHDRHMYEHTDNLCLTNVLYRSPDAFQFLSGLNQLLPQEKDGHYPSHWRVNQSTLQQVRQLVTQMEQAEENTESHALASRELTFMQLLVLLRRSSLVEGLENNDARLNQLMAWLEDHFAEEVSWETVADVFSLSLRTLHRQLKQHTGLTPQRYLNRLRLIKARHLLRHTDESVTDIAYRCGFGDSNHFSTLFRREFSWSPREIRQGRDASLQ
What is the function of this protein?
Activates expression of the rhaBAD and rhaT operons.
What are the official names of this protein?
HTH-type transcriptional activator RhaS, L-rhamnose operon regulatory protein RhaS.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GALC_MACMU
Sequence: MAEWLLSASRQRRVKAMTAAAGSAGRAAVPFLLCALLAPGGAYVLDDSDGLGREFDGIGAVSGGGATSRLLVNYPEPYRSQILDYLFKPNFGASLHILKVEIGGDGQTTDGTEPSHMHYALDENYFRGYEWWLMKEAKKRNPNITLIGLPWSFPGWLGKGFDWPYVNLQLTAYYVVTWIVGAKRYHDLDIDYIGIWNERSYNANYIKILRKMLNSQGLQRVKIIASDNLWESISAAMLLDAELFKVVDVIGAHYPGTHSVKDARLTGKKLWSSEDFSTLNSDTGAGCWGRILNQNYVNGYMTSTIAWNLVASYYEQLPYGRCGLMTAQEPWSGHYVVESPVWVSAHTTQFTQPGWYYLKTVGHLEKGGSYVALTDGLGNLTIIIETMSHKHSKCIRPFLPYFNVSQQFATFVLKGSFSEIPELQVWYTKLGKTSERFLFKQLDSLWLLDSNGSFTLKLQEDELFTLTTLTTGRKGSYLPPPKSQRFPSTYKDDFNVDYPFFSEAPNFADQTGVFEYFTNMEDPGEHHFTLRQVLNQRPITWAADASNTISIIGDYNWTNLTIKCDVYIETPDTGGVFIAGRVNKGGILIRSARGIFFWIFANGSYRVTGDLAGWIIYALGHVEVTAKTWYTLTLTIKGRFASGMLNDKSLWTDIPVNFPKNGWAAIGTHSFEFAQFDNFHVEATR
What is the function of this protein?
Hydrolyzes the galactose ester bonds of glycolipids such as galactosylceramide and galactosylsphingosine (PubMed:9192853).  Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon (By similarity).
What are the official names of this protein?
Galactocerebrosidase, GALCERase, Galactocerebroside beta-galactosidase, Galactosylceramidase, Galactosylceramide beta-galactosidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 59 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: PNP_STAA1
Sequence: MSQEKKVFKTEWAGRSLTIETGQLAKQANGAVLVRYGDTVVLSTATASKEPRDGDFFPLTVNYEEKMYAAGKIPGGFKKREGRPGDDATLTARLIDRPIRPLFPKGYKHDVQIMNMVLSADPDCSPQMAAMIGSSMALSVSDIPFQGPIAGVNVGYIDGKYIINPTVEEKEVSRLDLEVAGHKDAVNMVEAGASEITEQEMLEAIFFGHEEIQRLVDFQQQIVDHIQPVKQEFIPAERDEALVERVKSLTEEKGLKETVLTFDKQQRDENLDNLKEEIVNEFIDEEDPENELLIKEVYAILNELVKEEVRRLIADEKIRPDGRKPDEIRPLDSEVGILPRTHGSGLFTRGQTQALSVLTLGALGDYQLIDGLGPEEEKRFMHHYNFPNFSVGETGPVRAPGRREIGHGALGERALKYIIPDTADFPYTIRIVSEVLESNGSSSQASICGSTLALMDAGVPIKAPVAGIAMGLVTREDSYTILTDIQGMEDALGDMDFKVAGTKEGITAIQMDIKIDGLTREIIEEALEQARRGRLEIMNHMLQTIDQPRTELSAYAPKVVTMTIKPDKIRDVIGPGGKKINEIIDETGVKLDIEQDGTIFIGAVDQAMINRAREIIEEITREAEVGQTYQATVKRIEKYGAFVGLFPGKDALLHISQISKNRIEKVEDVLKIGDTIEVKITEIDKQGRVNASHRALEE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP23_DEBHA
Sequence: MSDLTDAPQANTDTLTTSAPDKLSGFEWWRRSLQYRTGMGISEDEKKQFEHDYRAKSLPKQCTDCVANLDWMLNYSPSVIFMMDHVKKIGGNISKSNIICDVCDDYKGGGFHPEGGILLCSNWITDKWQLEDILTHELVHAYDFLKFKVDLTNLKHHACTEIRASMLSGECRIFNEIKKTGLGDFGKKFQSCIKRRAILSVSANPNCKDTQEAEKVVNTVWQSCFNDTRPFERVYR
What is the function of this protein?
Has a dual role in the assembly of mitochondrial ATPase.  Acts as a protease that removes N-terminal residues of mitochondrial ATPase CF(0) subunit 6 at the intermembrane space side.  Also involved in the correct assembly of the membrane-embedded ATPase CF(0) particle, probably mediating association of subunit 6 with the subunit 9 ring (By similarity).
What are the official names of this protein?
Mitochondrial inner membrane protease ATP23.
What is the protein family that this protein belongs to?
Belongs to the peptidase M76 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Note=Associates loosely with the inner membrane.
Protein: RS17_ACAM1
Sequence: MAIKERIGVVVSDKMDKTVVVAVSNRVPHKKYGKIVGQTRRYKAHDEENACHVGDRVRIRESRPLSRTKRWAVTDVLVAANRP
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: NECT3_MOUSE
Sequence: MARTPGPAPLCPGGGKAQLSSAFPPAAGLLLPAPTPPPLLLLLIPLLLFSRLCGALAGSIIVEPHVTAVWGKNVSLKCLIEVNETITQISWEKIHGKSTQTVAVHHPQYGFSVQGDYQGRVLFKNYSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAVCVAATGKPVAQIDWEGDLGEMESSTTSFPNETATIVSQYKLFPTRFARGRRITCVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQWPDGLLASDNTLHFVHPLTVNYSGVYVCKVSNSLGQRSDQKVIYISDPPTTTTLQPTVQWHSSPADVQDIATEHKKLPFPLSTLATLKDDTIGTIIASVVGGALFLVLVSILAGVFCYRRRRTFRGDYFAKNYIPPSDMQKESQIDVLHQDELDSYPDSVKKENKNPVNNLIRKDYLEEPEKTQWNNVENLTRFERPMDYYEDLKMGMKFVSDERYNESEDGLVSHVDGSVISRREWYV
What is the function of this protein?
Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectins-like or other nectins, such as trans-interaction with NECTIN2 at Sertoli-spermatid junctions.  Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1.  Also involved in the formation of cell-cell junctions, including adherens junctions and synapses.  Induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation.  Plays a role in the morphology of the ciliary body.
What are the official names of this protein?
Nectin-3, Nectin cell adhesion molecule 3, Poliovirus receptor-related protein 3.
What is the protein family that this protein belongs to?
Belongs to the nectin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Postsynaptic cell membrane.
Protein: GLT10_HUMAN
Sequence: MRRKEKRLLQAVALVLAALVLLPNVGLWALYRERQPDGTPGGSGAAVAPAAGQGSHSRQKKTFFLGDGQKLKDWHDKEAIRRDAQRVGNGEQGRPYPMTDAERVDQAYRENGFNIYVSDKISLNRSLPDIRHPNCNSKRYLETLPNTSIIIPFHNEGWSSLLRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLEDYMALFPSVRILRTKKREGLIRTRMLGASVATGDVITFLDSHCEANVNWLPPLLDRIARNRKTIVCPMIDVIDHDDFRYETQAGDAMRGAFDWEMYYKRIPIPPELQKADPSDPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPYKVPAGVSLARNLKRVAEVWMDEYAEYIYQRRPEYRHLSAGDVAVQKKLRSSLNCKSFKWFMTKIAWDLPKFYPPVEPPAAAWGEIRNVGTGLCADTKHGALGSPLRLEGCVRGRGEAAWNNMQVFTFTWREDIRPGDPQHTKKFCFDAISHTSPVTLYDCHSMKGNQLWKYRKDKTLYHPVSGSCMDCSESDHRIFMNTCNPSSLTQQWLFEHTNSTVLEKFNRN
What is the function of this protein?
Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor.  Has activity toward Muc5Ac and EA2 peptide substrates.
What are the official names of this protein?
Polypeptide N-acetylgalactosaminyltransferase 10, Polypeptide GalNAc transferase 10, GalNAc-T10, pp-GaNTase 10, Protein-UDP acetylgalactosaminyltransferase 10, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.