PharMolix/UniProtQA huggingface dataset:
Protein: POLY_DROME
Sequence: RLVEFFRGRSRLPFIERRLAGRTLKMLIDTDAAKNYIRPVKELKNVMPVASPFSVSSIHGSTEIKHKCLMKVFKHISPFFLLDSLNAFDAIIGLDLLTQAGVKLNLAEDSLEYQGIAEKLHYFSCPSVNFTDVNDIVVPDSVKKEFKDTIIRRKKAFSTTNEALPFNTAVTATIRTVDNEPVYSRAYPTLMGVSDFVNNEVKQLLKDGIIRPSRSPYNSPTWVVDKKGTDAFGNPNKRLVIDFRKLNEKTIPDRYPMPSIPMILANLGKAKFFTTLDLKSGYHQIYLAEHDREKTSFSVNGGKYEFCRLPFGLRNASSIFQRALDDVLREQIGKICYVYVDDVIIFSENESDHVRHIDTVLKCLIDANMRVSQEKTRFFKESVEYLGFIVSKDGTKSDPEKVKAIQEYPEPDCVYKVRSFLGLASYYRVFIKDFAAIARPITDILKGENGSVSKHMSKKIPVEFNETQRNAFQRLRNILASEDVILKYPDFKKPFDLTTDASASGIGAVLSQEGRPITMISRTLKQPEQNYATNERELLAIVWALGKLQNFLYGSREINIFTDHQPLTFAVADRNTNAKIKRWKSYIDQHNAKVFYKPGKENFVADALSRQNLNALQNEPQSDAATIHSELSLTYTVETTDKPLNCFRNQIILEAARFPLKRNLVLFRSKSRHLISFTDKSWLLKTLKEVVNPDVVNAIHCDLPTLASFQHDLIAHFPATQFRHCKNVVLDITDKNEQIEIVTAEHNRAHRAAQENIKQVLRDYYFPKMGSLAKEVVANCRVCTQAKYDRHPKKQELGETPIPSYTGEMVHIDIFSTDRKLFLTCIDKFSKYAIVQPVVSRTIVDITAPLLQIINLFPNIKTVYCDNEPAFNSETVTSMLKNSFGIDIVNAPPLHSSSNGQVERFHSTLAEIARCLKLDKKTNDTVELILRATIEYNKTVHSVTRERPIEVVHPGAHERCLEIKARLVKAQQDSIGRNNPSRQNRVFEVGERVFVKNNKRLGNKLTPLCTEQKVQADLGTSVLIKGRVVHKDNLK
What are the official names of this protein?
Retrovirus-related Pol polyprotein from transposon gypsy.
Protein: MYO5_CANGA
Sequence: MAILKRGARNKTHQEPAKRGGNNIKKAAFETSKKKEVGVSDLTLLTSISDESINDNLKKRFLNGTIYTYIGHVLISVNPFRDLGIYTDAIMKSYQGKNRLEVPPHVYAISEAMYYNLKAYNENQCVIISGESGAGKTEAAKKIMEYIAATSSTHSESIGKIKDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIRFNSQFEPCAGNITNYLLEKQRVVGQITNERNFHIFYQFTKGASDNYRQTFGVQLPEQYVYTSASKCTSVDTIDDVKDFEATIKAMQVIGLAQEEQDQIFRMLAAILWIGNISFIENEEGNAQVRDTSVTDFVAYLLQVDSQSLIKALVERIVETNHGSRRGSVYHVPLNIVQATAVRDALAKAIYNNLFEWIVDRVNKSLHAYPGADKSIGILDIYGFEIFEHNSFEQICINYVNEKLQQIFIQLTLKSEQDTYAREKIQWTPIKYFDNKVVCDLIEAKRPPGIFAAMNDSVATAHADSSAADQAFAQRLSLFSSNPHFEQRQNKFVIKHYAGDVTYDVLGMTDKNKDQLQKDLVELVGTTTNAFLTTLFPNQVDKDNKRRPPTAGDKIIKSANELVETLSKAQPSYIRTIKPNQTKSPNDYDDHQVLHQVKYLGLQENVRIRRAGFAYRQGFEKFVERFYLLSPRCSYAGDYTWTGDILEAVRLILQDALIPEKEYQLGVTQVFIKTPETLFALENMRDKFWHNMAARIQRAWRRYLQRRIDAAVKIQRTIKERKEGNKFEKLRDYGTSLLGNKKERRSMSLLGYRAFMGDYLSCNESKSNGSYIKRQAGISEKVVFSFHGEALHSKFGRSAQRLKKTFILSPTTLYIIGQVRVQNAMQYTADYKINVNSILQLNMTNLQDDWVGIVLANSSMPDPLINLSFKTELITHLKTLNSKIQVKVGPTLEYQKKPGKMHSVKCQVSDTAPKYGDVYKSSTIFVRRGNPANSKSKKKPRKKSSGMSAPTTQSSKTLAPPRMSSNNQNTTVSQSLNGGMNVKPQTPASRSAKKPAPPPPGSKKPAPQPMAKKPAPHPTPQAQMQTQTQIPASQSSATQSSIPPPPPPPPSKTSEPQFEAAYDFPGSGNPSELPLMKGDIVYITKEEPSGWSLAKTLDGSKSGWVPTAYMVKHEGAKAPPPAPAVTASQPAIQNQSQPASAQTVAATSQVPASFGDGLVSALAARANKMRVESDEEAAASSDNDDDW
What is the function of this protein?
Type-I myosin implicated in the organization of the actin cytoskeleton.  Required for proper actin cytoskeleton polarization.  At the cell cortex, assembles in patch-like structures together with proteins from the actin-polymerizing machinery and promotes actin assembly.  Functions as actin nucleation-promoting factor (NPF) for the Arp2/3 complex (By similarity).
What are the official names of this protein?
Myosin-5, Class I unconventional myosin MYO5, Type I myosin MYO5.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, actin patch.
Protein: HELS_PYRCJ
Sequence: MEVSELPLDARLIAVLKERGVGRLFPPQVEAVRAGIFDGRSVLLCTATASGKSLLAEVAAVKAGLEGRMALYAVPLKALAYEKLVHFSYYRGLVKVGVSTGDFDSDDRRLHEFDVVVVTYEKLDSLLRHRPNWLGLVGVVVVDEIHYLGDPRRGPVLESIVAKLRHLGLKTQFIGLSATVGNAGEVAAWLGARLVESSWRPVPLREGVYHGGVIRFSDGSMQRVNAPGDAEVALAVDAVAGGGQALVFTNSRSSTVRLAKAVAKAMEAAGLVPRGAKALAEEVLKASSSKIIGRELADLVARGVAFHNAGLELEVRRLVEDGFRRGLLKVVVSTTTLAAGVNLPARRVVVADYERFDPALGREEIPVLEYRQMAGRAGRPGLDPYGEAVLVARSKGEAEYLMERYVRGQVEGVRSHILAEPNLRAHVLGAVGGGYAKSLDDLVDFFSNTLGAAQMKTSLKLSILRSKIGGVVEELVEWGFLERDGDFVYATELGRQVARLYLDPEVAAGYIRLIKSLRAGNVPAYLYVVLTAPDFPRVRRGRADKRVVEGILAALDVEEDEEFEDLARTASMLMAWIEEVDEDVIYEKFDVAPGDLRVYVDLFQWLGNAAAKLARLVGREEHGKRLEVVTARVVYGVREELLGLVTSLRGVGRVRARTLYNFGYRTLEDIARATVREIASLPGFGEKLAESVIEQARQMLAEGLRGEV
What is the function of this protein?
DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
What are the official names of this protein?
ATP-dependent DNA helicase Hel308.
What is the protein family that this protein belongs to?
Belongs to the helicase family. Hel308 subfamily.
Protein: MTNN_HALH5
Sequence: MTKIGIIGAMDEEVELLKSKLSNCSERTIAECEFYTGTIEGKEIVLLKSGIGKVNAAIGTTLLIQLFQPTAIINTGSAGGLDSSLHVGDLAISTEVRYNDVDATVFGYEFGQVPQMPAFYQPDDMLIDIAIEAAKTVGIPSKKGLILSGDSFMSDAALVEQLKRRFNYPLCSEMEAGAIAQVCHRFGVPFVIIRSLSDIAGAEAKVSYDEFLETASVNSANLVLAIVGRLG
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: PUR7_SERP5
Sequence: MQKLAELYRGKAKTVYTTENPDLLVLEFRNDTSALDGQRIEQFDRKGMVNNKFNHFIMSKLEEAGIPTQMERLLSDNEVLVKKLDMVPVECVIRNRAAGSLVKRLGIEEGLVLNPPLFDLFLKNDEMHDPMVNESYCETFGWVNKQHLARMRELSYQANDVLSKLFDDAGLILVDFKLEFGLFNGEVVLGDEFSPDGSRLWDKNTLDKMDKDRFRQSLGGLIEAYEEVARRIGVKLD
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: RNS12_MOUSE
Sequence: MVLMVVVFLLLLFWENELTEDVVLTSIEQLHVDYPQNAVPLRYCNYMILQRVIREPDHRCRKVHVFIHERPQKINRVCTSSKKMSCPNDSDLFCFQSETKFRMTVCQLIDGTTYPACRYQISPIKGFVLVTCDDLGPVDLQGYVE
What is the function of this protein?
Does not exhibit any ribonuclease activity.
What are the official names of this protein?
Probable inactive ribonuclease-like protein 12.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: ACLY_BOVIN
Sequence: MSAKAISEQTGKELLYKYICTTSAIQNRFKYARVTPDTDWARLLQDHPWLLSQSLVVKPDQLIKRRGKLGLIGVNLTLDGVKSWLKPRLGQEATVGKATGFLKNFLIEPFVPHTQEEEFYVCIYATREGDYVLFHHEGGVDVGDVDAKAQKLLVGVDEKLNPEDIKKHLLVHAPEDKKEILASFISGLFNFYEDLYFTYLEINPLVVTKDGVYVLDLAAKVDATADYICKVKWGDIEFPPPFGREAYPEEAYIADLDAKSGASLKLTLLNPKGRIWTMVAGGGASVVYSDTICDLGGVNELANYGEYSGAPSEQQTYDYAKTILSLMTREKHPDGKILIIGGSIANFTNVAATFKGIVRAIRDYQGPLKEHEVTIFVRRGGPNYQEGLRVMGEVGKTTGIPIHVFGTETHMTAIVGMALGHRPIPNQPPTAAHTANFLLNASGSTSTPAPSRTASFSESRTDEVAPAKKAKPAMLQGKSATLFSRHTKAIVWGMQTRAVQGMLDFDYVCSRDEPSVAAMVYPFTGDHKQKFYWGHKEILIPVFKNMADAMKKHPEVDVLINFASLRSAYDSTMETMNYAQIRTIAIIAEGIPEALTRKLIKKADQKGVTIIGPATVGGIKPGCFKIGNTGGMLDNILASKLYRPGSVAYVSRSGGMSNELNNIISRTTDGVYEGVAIGGDRYPGSTFMDHVLRYQDTAGVKMIVVLGEIGGTEEYKICRGVTEGRITKPVVCWCIGTCAAMFSSEVQFGHAGACANQASETAVAKNQALKEAGVFVPRSFDELGEIIQSVYEDLVARGVIVPAQEVPPPTVPMDYSWARELGLIRKPASFMTSICDERGQELIYAGMPITEVFKEEMGIGGVLGLLWFQKRLPKYSCQFIEMCLMVTADHGPAVSGAHNTIICARAGKDLVSSLTSGLLTIGDRFGGALDAAAKMFSKAFDSGIIPMEFVNKMKKEGKLIMGIGHRVKSINNPDMRVQILKDYVRQHFPATPLLDYALEVEKITTSKKPNLILNVDGLIGVAFVDMLRHCGSFTREEADEYIDIGALNGIFVLGRSMGFIGHYLDQKRLKQGLYRHPWDDISYVLPEHMSM
What is the function of this protein?
Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis.
What are the official names of this protein?
ATP-citrate synthase, ATP-citrate (pro-S-)-lyase, Citrate cleavage enzyme.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: TRXB_METJA
Sequence: MIHDTIIIGAGPGGLTAGIYAMRGKLNALCIEKENAGGRIAEAGIVENYPGFEEIRGYELAEKFKNHAEKFKLPIIYDEVIKIETKERPFKVITKNSEYLTKTIVIATGTKPKKLGLNEDKFIGRGISYCTMCDAFFYLNKEVIVIGRDTPAIMSAINLKDIAKKVIVITDKSELKAAESIMLDKLKEANNVEIIYNAKPLEIVGEERAEGVKISVNGKEEIIKADGIFISLGHVPNTEFLKDSGIELDKKGFIKTDENCRTNIDGIYAVGDVRGGVMQVAKAVGDGCVAMANIIKYLQKL
What are the official names of this protein?
Putative thioredoxin reductase, TRXR.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GP183_BOVIN
Sequence: MDIKMDNFTTPSAASLESDCDLYAHHHTARILMPLHYSIVFIIGLVGNLLALIVIIQNRKKINSTTLYSTNLVISDILFTTALPTRIAYYALGFDWRIGDALCRITALVFYINTYAGVNFMTCLSIDRFFAVVHPLRYNKIKRIEHAKCICIFVWILVFGQTLPLLINPMSKQEAERTTCMEYPNFEETKSLPWILLGACFIGYVLPLVIILICYSQICCKLFKTAKQNPLTEKSGVNKKALNTIIFIIVVFVVCFTPYHVAIIQHMIKKLRLPGLLECSQRHSFQISLHFTVCLMNFNCCMDPFIYFFACKGYKRKVMKMLKRQVSVSISSAVRSAPEENSREMTETQMMIHSKSLNGK
What is the function of this protein?
G-protein coupled receptor expressed in lymphocytes that acts as a chemotactic receptor for B-cells, T-cells, splenic dendritic cells, monocytes/macrophages and astrocytes (By similarity).  Receptor for oxysterol 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC) and other related oxysterols (By similarity).  Mediates cell positioning and movement of a number of cells by binding the 7-alpha,25-OHC ligand that forms a chemotactic gradient (By similarity).  Binding of 7-alpha,25-OHC mediates the correct localization of B-cells during humoral immune responses (By similarity).  Guides B-cell movement along the B-cell zone-T-cell zone boundary and later to interfollicular and outer follicular regions (By similarity).  Its specific expression during B-cell maturation helps position B-cells appropriately for mounting T-dependent antibody responses (By similarity).  Collaborates with CXCR5 to mediate B-cell migration; probably by forming a heterodimer with CXCR5 that affects the interaction between of CXCL13 and CXCR5 (By similarity).  Also acts as a chemotactic receptor for some T-cells upon binding to 7-alpha,25-OHC ligand (By similarity).  Promotes follicular helper T (Tfh) cells differentiation by positioning activated T-cells at the follicle-T-zone interface, promoting contact of newly activated CD4 T-cells with activated dendritic cells and exposing them to Tfh-cell-promoting inducible costimulator (ICOS) ligand (By similarity).  Expression in splenic dendritic cells is required for their homeostasis, localization and ability to induce B- and T-cell responses: GPR183 acts as a chemotactic receptor in dendritic cells that mediates the accumulation of CD4(+) dendritic cells in bridging channels (By similarity).  Regulates migration of astrocytes and is involved in communication between astrocytes and macrophages (By similarity).  Promotes osteoclast precursor migration to bone surfaces (By similarity).  Signals constitutively through G(i)-alpha, but not G(s)-alpha or G(q)-alpha (By similarity).  Signals constitutively also via MAPK1/3 (ERK1/2) (By similarity).
What are the official names of this protein?
G-protein coupled receptor 183.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CCA_STRGC
Sequence: MRLETLPSEFQEALPVLEKIKAAGFEAYFVGGSVRDALLQRPIHDVDIASSSYPEETKRIFDRTVDVGIEHGTVLVLENNREYEVTTFRTEDVYVDYRRPSKVSFVRSLEEDLKRRDFTINALALDENGQLIDLFQGLDDLENRILRAVGTPAERFNEDALRIMRGFRFQATLNFDLEQDTLSAMTDCAPLLEKISVERIFIEFDKLLLAPFWRKGLEALLTSGAIEFLPDLKGSRAKLEQLFELDSDFCFSASEQAWAALLLALKTQEVQRFLRIWKTSREFAKRVADIVEIVTIRSERDLTKRDCYDYDIDLLLQAEELRQAQGLAVDFSAIHNLDASLTIHSKQEMVVNGGMLMRDFGFEPGPKLGQILKELEYAIVDGHLPNDLEAIYAYIKEKK
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
Protein: EX7L_MYCMS
Sequence: MEKILTVQELNEALKTLIENKQEFKDIYVQGELSNLTFNKSGHIYFSIKEQDAAINCMMWKTNAYKIQSLNLEDGMQIICYGRLTYYIPTGRVSFEVRDIQIHGIGDLQKIFEQRYKELEQKGWFDPNLKKSIPEFVKNVGIITADSGAAIYDLIRTVHRRLPLINIYLFPAQVQGDKAEIDITNKIKQANNFKIDLDVLIVGRGGGSYEDLWAFNELEVLQAIKNSHIPIISAVGHEPDWVLSDYVADIRAATPTAAGELVSKSIIEIKNQLKHYYQNYKTLILNKLDFFNEKINNYKKDQTKYIKDNFSFKYLQLKQLSIDNTKWTKNKIDSVIYKLEDYKHSINNSIIHIINSQNKALKNYLIADEQKILNYLKKQISEFNYTISSFKGHINQILKYEELSFDTLENKLNSLDPLKPLQNGYSIVTNLNHQKIRSYKQVKLNEDLKVILTDSKLTVTIKEVKTNEQ
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YGIB_ECOBW
Sequence: MKRTKSIRHASFRKNWSARHLTPVALAVATVFMLAGCEKSDETVSLYQNADDCSAANPGKSAECTTAYNNALKEAERTAPKYATREDCVAEFGEGQCQQAPAQAGMAPENQAQAQQSSGSFWMPLMAGYMMGRLMGGGAGFAQQPLFSSKNPASPAYGKYTDATGKNYGAAQPGRTMTVPKTAMAPKPATTTTVTRGGFGESVAKQSTMQRSATGTSSRSMGG
What are the official names of this protein?
UPF0441 protein YgiB.
What is the protein family that this protein belongs to?
Belongs to the UPF0441 family.
Protein: ZC21A_BOVIN
Sequence: MEGLEENGSVQVGELLPCKICGRTFFPVALKKHGPICQKTATKKRKTFDSSRQRAEGTDIPTVKPLKPRPEPPKKPSNWRRKHEEFIATIRAAKGLGQVLKEGGKLPPPPPPSYDPDYIQCPYCQRRFNENAADRHINFCKEQAARISNKGKFSTDTKGKSTSRTQYKPPALKKFNSPGTTSSGSSRLPQPSGTSKTVVGAPSGKVSSVSSSSGNKLQTLSPSHKGIPAPHVGTNIKPRNSTPPSLARNPASGVLTSKRKTYSDSYMARPDGDYISSFNGGNTKGIEGNSAGHLPKFCHECGTKYPVEWAKFCCECGVRRMVL
What are the official names of this protein?
Zinc finger C2HC domain-containing protein 1A.
What is the protein family that this protein belongs to?
Belongs to the ZC2HC1 family.
Protein: CCR5_BOVIN
Sequence: MDYQTSTPLYDIDYGMSEPCQKLNVRQIAARLLPPLYSLVFIFGFVGNMLVVLILINCKKLKSMTDIYLLNLAISDLLFIITIPFWAHYAADQWVFGNTMCQLFTGFYFIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGAATSVVTWVVAVFASLPGIIFTKSQKEGSRHTCSPHFPSSQYHFWKNFQTLKIVILGLVLPLLVMIVCYSGIIKTLLRCRNEKKKHKAVRLIFVIMIVYFLFWAPYNIVLLLSTFQEFFGLNNCSGSNRLDQAMQVTETLGMTHCCINPIIYAFVGEKFRNYLLRFFRKYFASRFCKGCPVFQGEAPERVSSVYTRSTGEQEISVGL
What is the function of this protein?
Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level.  May play a role in the control of granulocytic lineage proliferation or differentiation.  Participates in T-lymphocyte migration to the infection site by acting as a chemotactic receptor.
What are the official names of this protein?
C-C chemokine receptor type 5, C-C CKR-5, CC-CKR-5, CCR-5, CCR5.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HAK9_ORYSJ
Sequence: MDPEFGRGMAPRKREPWRTTLLLAYQSLGVVYGDLSISPLYVYKSTFAEDITHSESNEEIFGVLSFVFWTLTLIPLIKYVSIVLRADDNGEGGTFALYSLICRHANVSLLPNRQVADEELSTYKLEYPPEVANRSRIKEWLEKHKTLQTALLIMVMIGTCMVIGDGVLTPAISVFSAVSGLELSLSRDQHEYAVIPITCVILVFLFALQHYGTHRVGFLFAPIVLAWLICMSMLGLYNIIHWNPQVYRALNPYYMLKFLRKTKKSGWMSLGGILLCMTGSEAMFADLGHFSYSAIQLAFTTLVYPALILGYMGQAAYLSKHHTLNSTYQIGYYISVPESVRWPVLVLAILASVVGSQAIISGTFSIINQSQSLSCFPRVKVVHTSENIHGQIYIPEINWLLMVLCIAVTVGFRDTKHMGNASGLAVITVMLVTTCLTSLVIMLCWHRSPALALVFFLFFGSIEVLYFSASLIKFREGAWLPIMLALILMAVMFIWHHTTIKKYEFDLHNKVTLEWLLALGDKLGMVRVPGIGLVYTDLTSGVPANFSRFVTNLPAFHRVLVFVCVKSVPVPHVLPAERYLVGRVGPAGHRSYRCIVRYGYRDVHQDVDSFEAELVESLATFIKLDALYHRCSDAGSGSEQLDDGRYERENALTVIGTNPLRRCLSYEASHDGVSSVDAARSPNGIVEVPAAAAAAPVTKKVRFVVEAASPEVEKGVVEELQELCEAREAGTAFILGHSHVQTKPGSSLLKKLAVGVGYNFLRRNCRGPDVVLRVPPASLLEVGMVYVL
What is the function of this protein?
High-affinity potassium transporter.
What are the official names of this protein?
Probable potassium transporter 9, OsHAK9.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72.3) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: G6PI_SHELP
Sequence: MTKLTQQDAWAQLEAQAAKLPHMRELFEADPQRFDKMSLSACGLLLDYSKNRADEQTLEQLFKLAKSAGLSDKIHAMFDGEIINNTEKRAVLHTALRAEADEVILVDGQNIVPEVKQTQAKMAKFVEAVTSGEWKGYTGKAITDIVSIGIGGSFLGPKIVTQALRPYWNPALKCHFVANVDATSLCEKLRLVDPETTLFVMSSKSFGTQETLTNTLSAKAWFLKNGGTQVDIAKHFVAVTSNVAKATEFGMDADNIFPMWDWVGGRYSLWSAIGLPIALLIGMDNFYQLLAGAKSMDKHFVEAPLEQNMPVIMGLFSLLYGNFYQAQSHVVLTYDHYLRGLPAYFQQLDMESNGKSVTLNGDNVDHATGPVIWGGEGTNGQHAYHQLLHQGTALIPADFILPLQSHNPLGEHHVQLASNCFGQTQALMQGRTFDEALAELDGSSQSQEEKALIAKHKVMEGNKPSNTLLMDKLTPETLGALIALYEHRTFVQGAIWDINSFDQWGVELGKTLGNDVLARLQSDEEAKALDASSNALINLFRRGHL
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRAF_GRASX
Sequence: LFGFLIKLIPSLFGALSNIGRNRNQ
What is the function of this protein?
Thanks to its abundant amphiphilic alpha-helices, it may integrate into membrane phospholipids, leading to lysis of the membrane.  Its hemolytic activity is inhibited by phospholipids, but not by cholesterol.  Has antibacterial activity with a broad spectrum against various species of bacteria including both Gram-positive and Gram-negative groups.  Has also ichthyotoxic activity.
What are the official names of this protein?
Grammistin Gs F, Gs 1.
What is the protein family that this protein belongs to?
Belongs to the grammistin family. Group 1 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RBFA_PECAS
Sequence: MAKEFSRTQRVAQEMQKEIAIIIQREVKDPRIGMATVSGVEVSRDLAYAKVFVTFLNDNEPEQVKIAVKALQDASGFIRMMIGKAMRLRVVPELTFSYDNSLVEGMRMSNLVTNVVRNDTERRSVTGEDQED
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YURR_BACSU
Sequence: MKSYIIVGAGILGASTAYHLAKTGARVTVIDRKEPGQATDAAAGIVCPWLSQRRNQDWYQLAKGGARYYKDLIHQLEKDGESDTGYKRVGAISIHTDASKLDKMEERAYKRREDAPEIGDITRLSASETKKLFPILADGYESVHISGAARVNGRALCRSLLSAAEKRGATVIKGNASLLFENGTVTGVQTDTKQFAADAVIVTAGAWANEILKPLGIHFQVSFQKAQIMHFEMTDADTGSWPVVMPPSDQYILSFDNGRIVAGATHENDAGLDDLRVTAGGQHEVLSKALAVAPGLADAAAVETRVGFRPFTPGFLPVVGAVPNVQGLYAANGLGASGLTMGPFLGAELAKLVLGKQTELDLSPYDPAGALA
What are the official names of this protein?
Uncharacterized oxidoreductase YurR.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: UUP_ECOLI
Sequence: MSLISMHGAWLSFSDAPLLDNAELHIEDNERVCLVGRNGAGKSTLMKILNREQGLDDGRIIYEQDLIVARLQQDPPRNVEGSVYDFVAEGIEEQAEYLKRYHDISRLVMNDPSEKNLNELAKVQEQLDHHNLWQLENRINEVLAQLGLDPNVALSSLSGGWLRKAALGRALVSNPRVLLLDEPTNHLDIETIDWLEGFLKTFNGTIIFISHDRSFIRNMATRIVDLDRGKLVTYPGNYDQYLLEKEEALRVEELQNAEFDRKLAQEEVWIRQGIKARRTRNEGRVRALKAMRRERGERREVMGTAKMQVEEASRSGKIVFEMEDVCYQVNGKQLVKDFSAQVLRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRIHVGTKLEVAYFDQHRAELDPDKTVMDNLAEGKQEVMVNGKPRHVLGYLQDFLFHPKRAMTPVRALSGGERNRLLLARLFLKPSNLLILDEPTNDLDVETLELLEELIDSYQGTVLLVSHDRQFVDNTVTECWIFEGGGKIGRYVGGYHDARGQQEQYVALKQPAVKKTEEAAAAKAETVKRSSSKLSYKLQRELEQLPQLLEDLEAKLEALQTQVADASFFSQPHEQTQKVLADMAAAEQELEQAFERWEYLEALKNGG
What is the function of this protein?
Probably plays a role in ribosome assembly or function; overexpression suppresses cold-sensitive growth of a bipA deletion (Ref. 10) (Probable).  May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps.  Binds DNA at Holliday junctions.  May be involved in the correct segregation of nucleoids (PubMed:31665437).  Has ATPase activity, binds DNA non-sequence specifically; the presence of DNA does not change the ATPase activity (PubMed:16407313).  Mutations in this gene cause an increase in RecA-independent precise excision of transposons and insertion elements, and also reduce bacteriophage Mu growth (PubMed:6294054, PubMed:16407313, PubMed:19948254).
What are the official names of this protein?
ATP-binding protein Uup.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associates with ribosomes.
Protein: PYRI_CLOB6
Sequence: MLTINSIKNGIVIDHIQAGHGIKIFKYLGLEEADYRVALIMNAESSKLGKKDIIKIENIMEIDYKVLGFIDPTITIDVIENETIKEKIKLELPKTIENVIKCKNPRCITSIENYIPNEFYLVDEENGEYRCKYCDEIYSGGDINKL
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: PYRR_BACC4
Sequence: MQEKAVVLDDQMIRRALTRISHEIVERNKGVDNCVLVGIKTRGIFIAQRLAERIGQIEGKEMEVGELDITLYRDDLTLQSKNKEPLVKGSDIPVDITKKKVILVDDVLYTGRTVRAAMDALMDLGRPSQIQLAVLVDRGHRELPIRADYVGKNIPTSSEERIEVDLQETDQQDRVSIYDK
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: MNS60_HUMAN
Sequence: MKDVVVVVTGLAAMEPLTARRMMVGRTAAETTTTGTWTTVHILASMAARRASMTMTTHLRSRVRRIPTRPPRAPRLSVGGGGGTGTAPPARQASPETATIGTRTIGPSKGRRRRRRRMRRRRRRPVTSSC
What is the function of this protein?
Acts as a late-stage inhibitor of pre-60S ribosome assembly by preventing pre-60S ribosome export from nucleus.
What are the official names of this protein?
Ribosome biogenesis inhibitor MINAS-60, MINAS-60.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: GAL1_YERP3
Sequence: MSLKQHTQTIFRQQFDRESDITIKAPGRVNLIGEHTDYNDGFVLPCAINYETVISCGKRDDRQIRVIAADYENQQDIFSLDAPIVPHPEYRWADYVRGVVKHLQMRNADFGGADLVICGNVPQGAGLSSSASLEVAVGQALQSLYQLPLSGVELALNGQEAENQFVGCNCGIMDQLISALGKKDHALLIDCRTLETRAVPMPENMAVVIINSNIQRGLVDSEYNTRRQQCEAAARFFGVKALRDVEPSLFFSIQDELDPVVAKRARHVISENARTLAAADALAAGNLKLMGQLMQESHISMRDDFEITVPPIDRLVEIVKSVIGDQGGVRMTGGGFGGCIIALMPLELVEQVRTTVAQEYPAHSGGKKETFYVCQASQGAGLC
What is the function of this protein?
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.