PharMolix/UniProtQA huggingface dataset:
Protein: FUT1_AOTNA
Sequence: MWPLSHRHLCLAFLLVCVLSAISFFLHIHQDSIRHGLGLSVLCPDRRLVTPPVAIFCLPGTPMSPNTSSPCPQNSASLSGTWTIYPDGRFGNQMGQYATLLALAQLNGRRAFILPAMHAALAPVFRITLPVLAPEVDSRTPWRELRLHDWMSEEYADLGDPFLKLSGFPCSWTFFHHLREQIRSEFTLHDHLREEAQSVLRRLRLGRSGDRPRTFVGVHVRRGDYLQVMPQRWKGVVGNGAYLREAMDWFRARHEAPVFVVTSNGMDWCRENIDASKGDVMFAGDGQEASPWKDFALLTQCNHTIMTIGTFGFWAAYLAGGDTVYLANFTLPDSEFLKIFKPEAAFLPEWVGINADLSPLWTLAEP
What is the function of this protein?
Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the terminal galactose residue of glycoconjugates through an alpha(1,2) linkage leading to H antigen synthesis that is an intermediate substrate in the synthesis of ABO blood group antigens.  H antigen is essential for maturation of the glomerular layer of the main olfactory bulb, in cell migration and early cell-cell contacts during tumor associated angiogenesis (By similarity).  Preferentially fucosylates soluble lactose and to a lesser extent fucosylates glycolipids gangliosides GA1 and GM1a (By similarity).
What are the official names of this protein?
Galactoside alpha-(1,2)-fucosyltransferase 1, Alpha(1,2)FT 1, Fucosyltransferase 1, GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1, Type 1 galactoside alpha-(1,2)-fucosyltransferase FUT1, Type 2 galactoside alpha-(1,2)-fucosyltransferase FUT1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 11 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Protein: YJHI_ECOLI
Sequence: MVRKGCNSLVRAEKILTHIAWVGMASYMELLNKFQYPKSSLLNLLNVMVDCGFLIKNKNGYYSLGIKNYELGCQALHRQNIFEVTKRPMQELSLKSGLVCHLGAMESISAIYLDKIESPDSVPTSKSWIGKKLELHITALGKALLAWKTREELDYFLEALTLTPHTRNTFTDKKLFLEELQKTRLRGWAIDNEESTYGAVCLSMPVFNMYNRVNYAISLSGDPVVYSGNKIDSYLELLRKCAEQISYGLGYRNENEHLRKGN
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator YjhI.
Protein: PP2B4_ARATH
Sequence: MNTQILSQKTRYSAYIVYKTIYRFHGFKHIGVGFIGHGTPKAKRWERKDLGNDWLGCKKKFKASKKQKFYSNKSTFTDKPITHLIKLEEGEDGWMATEFGEFFAEGGGLLDCDEIVLSVIDIDYAYWKCGLIIQGIDIRPTKSP
What are the official names of this protein?
Putative protein PHLOEM PROTEIN 2-LIKE B4, AtPP2-B4.
Protein: RL29_SALG2
Sequence: MKAKELREKSVEELNTELLNLLREQFNLRMQAASGQLQQSHLLKQVRRDVARVKTLLTEKAGA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: NRN1_MOUSE
Sequence: MGLKLNGRYISLILAVQIAYLVQAVRAAGKCDAVFKGFSDCLLKLGDSMANYPQGLDDKTNIKTVCTYWEDFHSCTVTALTDCQEGAKDMWDKLRKESKNLNIQGSLFELCGSSNGAAGSLLPALSVLLVSLSAALATWFSF
What is the function of this protein?
Promotes neurite outgrowth and especially branching of neuritic processes in primary hippocampal and cortical cells.
What are the official names of this protein?
Neuritin, Candidate plasticity gene 15 protein.
What is the protein family that this protein belongs to?
Belongs to the neuritin family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor. Synapse.
Protein: CRVP2_VARAC
Sequence: MILLKLYLTLAAILCQSRGTTSLDLDDLMTTNPEIQNEIINKHNDLRRTVDPPAKNMLKMSWGQHHCRECQTCSTEMQPKMSTHPVSGRKIGWVWVCGGKLLHVK
What is the function of this protein?
Blocks ryanodine receptors, and potassium channels.
What are the official names of this protein?
Cysteine-rich venom protein VAR2, CRVP, Cysteine-rich secretory protein VAR2, CRISP-VAR2.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Secreted.
Protein: KAD_PROM2
Sequence: MKRHLLFLGAPGAGKGTQAELLSQTNSYLHLSTGELLRKEIDMNTILGIQVKDIMNRGELVSDELVLKIVRQNLVKDNKGWILDGYPRNLSQANSLNEVLTEINQPLEVVFYLDIPEEVLIKRLLLRGRKDDTEKTIRTRVDIYKKTTEPLIQYFKDLSLLEYIDADRDLKTISSDIKQKMA
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYSY_KINRD
Sequence: MAEQRIDTQYEDLLRHVLATGTPKSDRTGTGTRSVFGHQLRYDLSAGFPLVTTKRVHFKSIALELLWFLRGDGNVRWLQERGVTIWDEWADENGDLGPVYGVQWRSWPTPDGRHVDQIAQVLHTLRTDPDSRRMVVSAWNVAELDRMALAPCHAFFQFHVADGKLSCQLYQRSADLFLGVPFNIASYALLTHLVAAEVGLEVGDFVWTGGDVHVYDNHVEQVTEQLTRTPYPFPRLAVRPAGLFEHEYEDFEVLDYRHHPAIKAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPC41_MYCTO
Sequence: MLLCDTNIWLALALSGHVHHRASRAWLDTINAPGVIHFCRATQQSLLRLLTNRTVLGAYGSPPLTNREAWAAYAAFLDDDRIVLAGAEPDGLEAQWRAFAVRQSPAPKVWMDAYLAAFALTGGFELVTTDTAFTQYGGIELRLLAK
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  An RNase.  Its toxic effect is neutralized by coexpression with cognate antitoxin VapB41 (By similarity).
What are the official names of this protein?
Ribonuclease VapC41, RNase VapC41, Toxin VapC41.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: NIKR_THEKO
Sequence: MKIIRFGVSVPEELLEKFDQIIAEKGYVNRSEAIRDLMRDFIVRHEWEAGDKEVAGTITMLYNHDEADVVKELLDLQHDYLNEIISSIHVHMDEHNCLEVVIVKGKAKRIKEIADRLLSLKGVKHGKLVMTGTGKELV
What is the function of this protein?
Transcriptional regulator.
What are the official names of this protein?
Putative nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: RS2_PSELT
Sequence: MPVITMKQLLEAGVHFGHRTRRWNPKMAPYIYGARKGIYIIDLQKTLKLVEEACDFVKSKASEGATMIFVGTKKQAQHVVKEEAGKCGAFYVNNRWLGGLITNFKTIKPRIDKLIELEEMEKNGELAKLPKKEQSRLRKALEKLRKNLGGLKAMDRIPDIIYVIDPRKERIAVAEANKMGIPVIGVVDTNCDPDPVDFVIPANDDAIRSIKLITSKIAEAYLEGREGVSFTEETPSEPIQSDSSEEEEGSLDISDLFEDTDLKEEE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: Y1423_HAEIN
Sequence: MESIKLSQKAEEEIVNAARMAALSNLTEKSQNLITLEDIAIYFGRHYQTVAKIISKLPNFPKPVTPVTVDQQNSRPRYIAGEVVRWGRINAKPY
What are the official names of this protein?
Uncharacterized protein HI_1423.
Protein: RL22_PROM1
Sequence: MTTSSTKTTAQAHGRYIRGSASKVRRVLDQIRGRTYRDALIMLEFMPYRSTEPITKVLRSAVANAENNLGLDPSSLMISTATADMGPPMKRYRPRAQGRAFAIKKQTCHISISVSATQSTNSEDSD
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RF1_PYRAE
Sequence: MSFNRPPNGVYYIRSAVELRAFVNLLKKFKGYATTLITLYINAERPIPDVVNLLRSEWSTAANIKDKTTRTHVQDTLERIINNLKGEAKAPENGMAVFAGFHMINQGNYEWVYYVVIPPQPINTFKYICDTAFHTELLEDQLHAGVVYGIVVIERGEAVIALLKGGQWEVVKSVEFFVPGKHHAGGQSANRFKRQTEHLAEAFYKMVAEEANKIFLQIPTLKGIIVAGPGPTKEDFLEEGGLDYRLKDKILAIVPACCANEYGVMEAIRNAQEQLKESEYVKAKEVMDKVMYYAVKKSEYLVYGRERALKALEMGIADIIVIAEELGEDAVLEVIMKAEEKGIKVEVVPRGVEESKTLMQAFGGYVALLSTPVWVLEQQLSIAEAAQR
What is the function of this protein?
Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
What are the official names of this protein?
Peptide chain release factor subunit 1, Translation termination factor aRF1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRF_STRPI
Sequence: MREHRPIIALDFPSFEVVKEFLALFPAEESLYLKVGMELYYAAGPEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKILSQLGVDMTNVHAAGGVEMMKAAREGLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEVQVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPVAAYHAIKDEWTQDWN
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: SORC3_HUMAN
Sequence: MEAARTERPAGRPGAPLVRTGLLLLSTWVLAGAEITWDATGGPGRPAAPASRPPALSPLSPRAVASQWPEELASARRAAVLGRRAGPELLPQQGGGRGGEMQVEAGGTSPAGERRGRGIPAPAKLGGARRSRRAQPPITQERGDAWATAPADGSRGSRPLAKGSREEVKAPRAGGSAAEDLRLPSTSFALTGDSAHNQAMVHWSGHNSSVILILTKLYDFNLGSVTESSLWRSTDYGTTYEKLNDKVGLKTVLSYLYVNPTNKRKIMLLSDPEMESSILISSDEGATYQKYRLTFYIQSLLFHPKQEDWVLAYSLDQKLYSSMDFGRRWQLMHERITPNRFYWSVAGLDKEADLVHMEVRTTDGYAHYLTCRIQECAETTRSGPFARSIDISSLVVQDEYIFIQVTTSGRASYYVSYRREAFAQIKLPKYSLPKDMHIISTDENQVFAAVQEWNQNDTYNLYISDTRGIYFTLAMENIKSSRGLMGNIIIELYEVAGIKGIFLANKKVDDQVKTYITYNKGRDWRLLQAPDVDLRGSPVHCLLPFCSLHLHLQLSENPYSSGRISSKETAPGLVVATGNIGPELSYTDIGVFISSDGGNTWRQIFDEEYNVWFLDWGGALVAMKHTPLPVRHLWVSFDEGHSWDKYGFTSVPLFVDGALVEAGMETHIMTVFGHFSLRSEWQLVKVDYKSIFSRHCTKEDYQTWHLLNQGEPCVMGERKIFKKRKPGAQCALGRDHSGSVVSEPCVCANWDFECDYGYERHGESQCVPAFWYNPASPSKDCSLGQSYLNSTGYRRIVSNNCTDGLREKYTAKAQMCPGKAPRGLHVVTTDGRLVAEQGHNATFIILMEEGDLQRTNIQLDFGDGIAVSYANFSPIEDGIKHVYKSAGIFQVTAYAENNLGSDTAVLFLHVVCPVEHVHLRVPFVAIRNKEVNISAVVWPSQLGTLTYFWWFGNSTKPLITLDSSISFTFLAEGTDTITVQVAAGNALIQDTKEIAVHEYFQSQLLSFSPNLDYHNPDIPEWRKDIGNVIKRALVKVTSVPEDQILIAVFPGLPTSAELFILPPKNLTERRKGNEGDLEQIVETLFNALNQNLVQFELKPGVQVIVYVTQLTLAPLVDSSAGHSSSAMLMLLSVVFVGLAVFLIYKFKRKIPWINIYAQVQHDKEQEMIGSVSQSENAPKITLSDFTEPEELLDKELDTRVIGGIATIANSESTKEIPNCTSV
What are the official names of this protein?
VPS10 domain-containing receptor SorCS3.
What is the protein family that this protein belongs to?
Belongs to the VPS10-related sortilin family. SORCS subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: UVRB_TREPS
Sequence: MKEFKLHASFQPAGDQIAAIDALVRGLHAGARFQTLKGVTGSGKTFTVANVIARVQKPTLVISHNKTLSAQLYREFKGFFPDNAVEYFVSYYDYYQPESYVPARDLYIEKDASINAEINRMRLSATFSLMERRDVIVVATVSCIYGLGLPESWRDLRIHVEVNQCLDLEDLKRQLVSLQYERNDAVLECGRFRVRGDVIEIFPAYLEEFYRIECDWDRVVRIRRIHPVSGAVLREFEELTVYPAKHFVLKEDAIPRAMDRIRQELDERLVQLTQENKLAEAARLKTRTEYDLEMLGEMGYCHGIENYSAPIAGRKSGEPPVTLLHYFPKDFVLFVDESHVTLPQLGAMYEGDRVRKQNLIDFGFRLPCARDNRPLKDSEFEALLNQAVFISATPGVKERTQSVQIVEQLIRPTGLLDPCIEVRKTDGQIEDICQRVKACSARNERSLVLTLTKKMAEDLTDYFNGLGIRTKYVHSEIETIERVEILTSLRAGECEVLVGINLLREGIDLPEVAFIAILDANIVGFLRSTTSLIQIIGRAARNARGTVVMYADAISDAMREAIEETARRRKIQMAYNRAHGITPRTIKKSIEDILVREQEVKKDAARVQVAPLLRAADADVRTHAARKKMVQALRLHMKVCARELRFEEAALIRDKILQLQRQDEQNGV
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AHL11_ARATH
Sequence: MDRRDAMALSGSGSYYIQRGIPGSGPPPPQTQPTFHGSQGFHHFTNSISPFGSNPNPNPNPGGVSTGFVSPPLPVDSSPADSSAAAAGALVAPPSGDTSVKRKRGRPRKYGQDGGSVSLALSPSISNVSPNSNKRGRGRPPGSGKKQRLSSIGEMMPSSTGMSFTPHVIVVSIGEDIASKVISFSHQGPRAICVLSASGAVSTATLLQPAPSHGTIIYEGLFELISLSTSYLNTTDNDYPNRTGSLAVSLASPDGRVIGGGIGGPLIAASQVQVIVGSFIWAIPKGKIKKREETSEDVQDTDALENNNDNTAATSPPVPQQSQNIVQTPVGIWSTGSRSMDMHHPHMDIDLMRG
What is the function of this protein?
Transcription factor that specifically binds AT-rich DNA sequences related to the nuclear matrix attachment regions (MARs).
What are the official names of this protein?
AT-hook motif nuclear-localized protein 11.
What are the subcellular locations of this protein?
Nucleus.
Protein: TUSC2_MOUSE
Sequence: MGASGSKARGLWPFASTPGGGGPEAAGSEQSLVRSRARAVPPFVFTRRGSMFYDEDGDLAHEFYEETIVTKNGQKRAKLRRVHKNLIPQGIVKLDPPRIHVDFPVILYEV
What are the official names of this protein?
Tumor suppressor candidate 2, Fusion 1 protein, Fus-1 protein, PDGFA-associated protein 2.
What is the protein family that this protein belongs to?
Belongs to the TUSC2 family.
Protein: RUVB_SALDC
Sequence: MIEADRLISAGATIAEDVADRAIRPKLLAEYVGQPQVRSQMEIFIQAAKRRGDALDHLLIFGPPGLGKTTLANIVANEMGVNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGATTRAGSLTSPLRDRFGIVQRLEFYQVPDLQHIVGRSARHMGLEMSDDGALEVARRARGTPRIANRLLRRVRDFAEVKHDGAISAEIAAQALDMLNVDAEGFDYMDRKLLLAVIDKFFGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFLQRTPRGRMATVRAWNHFGITPPEMP
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: PRIM_GAHVM
Sequence: MARFSSISDTLESDDSGIKVLFAVDGCAVSFSLALLTGQIPSTNSVYVIGYWDPSDRFSSIPFLDGDPNTNERISTTVCNLEDVPSPLRVEFCLLNQMASGMGGADLKLRTRAIFVCRFTSWSEMNAIANSIIYGTPIQAGVLQATISETETFMLHDEFNLALHVFLNGLSLKGRNKKDVCMSLNHNYISSVSENFPRGKRGLTGLYLQHEQKVTAAYRRIYGGSTTTAFWYVSKFGPDEKSLVLALRYYLLQAQEEVTGIATGYDLQAIKDICKTYAVSVNPNPTGFLAADLTSFSRLSRFCCLSYYSKGSVAIAFPSYVERRIMADIAEVDALREYIERDRPSLKISDLEFVKYIYLAYFECYNREQLKRHLKDVTVSLPDEDIYKKSSLGKCAVENFFTHVRSRLNVNDHIAHNVLPEQVEMGNKLVRKFGRARMYLSTTMTNESHFTGICECASVILKRLDTLEMKLQKYGWPSDRVDGSNLMADNQNNSTLIPYDKSRSSGMILECSNTHSRGGPMIVKRLLALVSADSRAGGIGPANMLMGIDSAIDGPLPVYRVGMSKGRQAFTVLMTECWERTIPSPGSAKAHLIKLNNSYGTSTEDLISRDLFLTSEIEQLIGSTVELPEITCGSADEQQYINRNEVFNGNLAIGNIVLDVDIHLRNPIPLRLMHAAIRGFRSGILRALALLLPKANIDHGSYPCYFYKSSCKKSRVMGGAPWMLHDAELAPDYSMFENAEFDLEMGIDDPLLIDQIDESLTRWSSESSRSVDLDPDKPCGCHDKIGLRVCIPVPSPYLLVGSKTLAGLSRIIQQAVLLERNFVETIGPYLKNYEIIDSGVYGHGRSLRLPFFGKIDENGIVSRRLVPFFVIPDDCADMEKFIVAHFEPKNFHFHSSIPLEKAAIILKDIGGEYAGFFERKITVNRDIFFGTRLSLSIALRERGVDINDCAAITTFVTDHILDDIITYVYEHIPDHAIEYQNLSVSCCVVKSDWILLQLIPNKTIGYRHGFTCVRFKHARARRASARSYLALNVDAHGRLCVCVIQQCFAAKCGNNKLRTLFTVDIDSKCRLEHQ
What is the function of this protein?
Essential component of the helicase/primase complex.  Unwinds the DNA at the replication forks and generates single-stranded DNA for both leading and lagging strand synthesis.  The primase initiates primer synthesis and thereby produces large amount of short RNA primers on the lagging strand that the polymerase elongates using dNTPs.
What are the official names of this protein?
DNA primase.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae DNA primase family.
What are the subcellular locations of this protein?
Host nucleus. Note=Requires the presence of the primase associated factor to properly localize in the host cell nucleus.
Protein: RS20_PROMM
Sequence: MANNKSSKKRVQIAERNRLENKSYKSAMRTLMKRCFSACSHYSQQPGETAKANVKASIDSAFSKIDKAVKRGVLHRNTAAHQKSRLSAAVKQAIEPAPST
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: TBA_NOTVI
Sequence: MRECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAIFVDLEPSVIDEVRTGTYRQLFHPEQLISGKEDAANNYARGHYTIGKEIIDQVLDRMRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPSYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPPTAVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGLDSYEGEEDEGEEY
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RS15_METVS
Sequence: MARLHSGKRGSSGSTKPLRTEVPEWVSMSAEEVQAKIVEMAKDGNQSAIIGNILRDMYGIPNVKLVTGKSVSSIMKDAGFYSEVPEDLFNLMKKAINLRNHLENNPRDIHSKVGLNLIESKIRRLVKYYKGTKVLPATWRYSPQTARLLVE
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: AMIF_HELPY
Sequence: MGSIGSMGKPIEGFLVAAIQFPVPIVNSRKDIDHNIESIIRTLHATKAGYPGVELIIFPEYSTQGLNTAKWLSEEFLLDVPGKETELYAKACKEAKVYGVFSIMERNPDSNKNPYNTAIIIDPQGEIILKYRKLFPWNPIEPWYPGDLGMPVCEGPGGSKLAVCICHDGMIPELAREAAYKGCNVYIRISGYSTQVNDQWILTNRSNAWHNLMYTVSVNLAGYDNVFYYFGEGQICNFDGTTLVQGHRNPWEIVTGEIYPKMADNARLSWGLENNIYNLGHRGYVAKPGGEHDAGLTYIKDLAAGKYKLPWEDHMKIKDGSIYGYPTTGGRFGK
What is the function of this protein?
Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide.  Probably involved in the nitrogen metabolism of H. pylori.
What are the official names of this protein?
Formamidase, Formamide amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family.
Protein: Y192_ALISL
Sequence: MSLMNLPEESRPREKLLALGPKSLTDAELLAIFLRTGIKGMNAIELADKLLKEFGSLRKLLGSNENEFCSHKGLGTAKFAQLQAVVEMTERYLFEKIEKEDALTSPEHTKRYLTRILRDRHREAFYVLFLDNQHRVLKGEVLFEGTIDAAAVYPREVVKRSIDYNAAAIILAHNHPSGVAEPSQADRRITKRISDAVELVDIRVLDHFVIGDGEIVSFAERGWI
What are the official names of this protein?
UPF0758 protein VSAL_I0192.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: MECI_STAAM
Sequence: MDNKTYEISSAEWEFMNIIWMKKYASANNIIEEIQMQKDWSPKTIRTLITRLYKKGFIDRKKDNKIFQYYSLVEESDIKYKTSKNFINKVYKGGFNSLVLNFVEKEDLSQDEIEELRNILNKK
What is the function of this protein?
Transcriptional repressor that constitutively blocks the transcription of the gene for the penicillin-binding protein MecA.  Binds DNA as a dimer (By similarity).
What are the official names of this protein?
Methicillin resistance regulatory protein MecI.
What is the protein family that this protein belongs to?
Belongs to the BlaI transcriptional regulatory family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANXA1_RAT
Sequence: MAMVSEFLKQACYIEKQEQEYVQAVKSYKGGPGSAVSPYPSFNPSSDVAALHKAIMVKGVDEATIIDILTKRTNAQRQQIKAAYLQETGKPLDETLKKALTGHLEEVVLAMLKTPAQFDADELRAAMKGLGTDEDTLIEILTTRSNQQIREITRVYREELKRDLAKDITSDTSGDFRNALLALAKGDRCEDMSVNQDLADTDARALYEAGERRKGTDVNVFNTILTTRSYPHLRKVFQNYRKYSQHDMNKALDLELKGDIEKCLTTIVKCATSTPAFFAEKLYEAMKGAGTRHKTLIRIMVSRSEIDMNEIKVFYQKKYGIPLCQAILDETKGDYEKILVALCGGN
What is the function of this protein?
Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades.  Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors.  Promotes rearrangement of the actin cytoskeleton, cell polarization and cell migration.  Promotes resolution of inflammation and wound healing.  Acts via neutrophil N-formyl peptide receptors to enhance the release of CXCL2.
What are the official names of this protein?
Annexin A1, Annexin I, Annexin-1, Calpactin II, Calpactin-2, Chromobindin-9, Lipocortin I, Phospholipase A2 inhibitory protein, p35.
What is the protein family that this protein belongs to?
Belongs to the annexin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell projection, cilium. Basolateral cell membrane. Lateral cell membrane. Cell membrane; Peripheral membrane protein. Apical cell membrane. Membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Secreted. Secreted, extracellular space. Cell membrane; Peripheral membrane protein; Extracellular side. Early endosome. Cytoplasmic vesicle membrane; Peripheral membrane protein. Secreted, extracellular exosome. Cytoplasmic vesicle, secretory vesicle lumen. Cell projection, phagocytic cup. Note=Colocalizes with actin fibers at phagocytic cups. Secreted, at least in part via exosomes and other secretory vesicles. Detected in exosomes and other extracellular vesicles. Secretion is increased in response to wounding and inflammation (By similarity). Alternatively, the secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in the protein translocation from the cytoplasm into ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion (By similarity). Detected in gelatinase granules in resting neutrophils. Neutrophil adhesion to endothelial cells stimulates secretion via gelatinase granules, but foreign particle phagocytosis has no effect. Displays calcium-dependent binding to phospholipid membranes (PubMed:3020049).