PharMolix/UniProtQA huggingface dataset:
Protein: RS19_CITBB
Sequence: MARSIKKGPFVDGHLEAKAQAEQAGSKKVIKTWSRRSTIIPEFIGLTFAVHNGKKFIPVFVTENMVGHKMGEFSPTRTFYGHAADKKSKLKKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: RSMH_AGGAN
Sequence: MTHLNAFSSVEHSTVLLHETVDGLALKENGIYIDGTFGRGGHSRLILSKLSANGKLIAIDRDPKAVAEAQKIQDPRFQIEHNTFSEILSICEKRGLVGKIDGILLDLGVSSPQLDDAARGFSFMKDGPLDMRMDDSKGISAAEWLQQVSEQDLAWVLKTFGEERFAKKIAKAIVNYNKSAVQNGSEFLTRTLQLAELIAHTVPFKDKHKHPATRSFQAIRIFINAELDELEKVLQSALTVLAPAGRLSVISFHSLEDRMVKHFMRKQSQGREIPKGLPLREDQIQRNQTLKVIGKAIMPTDAEIAQNPRARSAVLRVAERLN
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HLDE_HELPH
Sequence: MKKILVIGDLIADYYLWGKSERLSPEAPVPVLEVKKESKNLGGAANVANNLISLKAKVFLCGVVGDDLEGKHFISALKAREIDTSGILTDKTRCTTLKTRIIAQNQQIVRVDKEIKDPLNADLRKKLLDFFTEKIQEIDGVILSDYNKGVLDFELTQKMITLANQHHKLILCDPKGKDYSKYSHASLITPNRAELEHALHLKLDSHANLSKALQILKETYQIAMPLVTLSEQGIAFLEKGELVNCPTIAKEVYDVTGAGDTVIASLTLSLLESMSLKDACEFANAAAAVVVGKMGSALASLEEIALILNQTHPKILPLEKLLETLEHHQQKIVFTNGCFDLLHKGHASYLQKAKALGDILVVGLNSDNSIKRLKGNKRPIVSEKDRAFLLASLSCVDYVVVFEEDAPIKLIQALKPDILVKGADYLNKEVIGSEFAKETHLMEFEEGYSTSAIIEKIKRTHND
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: NOS2_HUMAN
Sequence: MACPWKFLFKTKFHQYAMNGEKDINNNVEKAPCATSSPVTQDDLQYHNLSKQQNESPQPLVETGKKSPESLVKLDATPLSSPRHVRIKNWGSGMTFQDTLHHKAKGILTCRSKSCLGSIMTPKSLTRGPRDKPTPPDELLPQAIEFVNQYYGSFKEAKIEEHLARVEAVTKEIETTGTYQLTGDELIFATKQAWRNAPRCIGRIQWSNLQVFDARSCSTAREMFEHICRHVRYSTNNGNIRSAITVFPQRSDGKHDFRVWNAQLIRYAGYQMPDGSIRGDPANVEFTQLCIDLGWKPKYGRFDVVPLVLQANGRDPELFEIPPDLVLEVAMEHPKYEWFRELELKWYALPAVANMLLEVGGLEFPGCPFNGWYMGTEIGVRDFCDVQRYNILEEVGRRMGLETHKLASLWKDQAVVEINIAVLHSFQKQNVTIMDHHSAAESFMKYMQNEYRSRGGCPADWIWLVPPMSGSITPVFHQEMLNYVLSPFYYYQVEAWKTHVWQDEKRRPKRREIPLKVLVKAVLFACMLMRKTMASRVRVTILFATETGKSEALAWDLGALFSCAFNPKVVCMDKYRLSCLEEERLLLVVTSTFGNGDCPGNGEKLKKSLFMLKELNNKFRYAVFGLGSSMYPRFCAFAHDIDQKLSHLGASQLTPMGEGDELSGQEDAFRSWAVQTFKAACETFDVRGKQHIQIPKLYTSNVTWDPHHYRLVQDSQPLDLSKALSSMHAKNVFTMRLKSRQNLQSPTSSRATILVELSCEDGQGLNYLPGEHLGVCPGNQPALVQGILERVVDGPTPHQTVRLEALDESGSYWVSDKRLPPCSLSQALTYFLDITTPPTQLLLQKLAQVATEEPERQRLEALCQPSEYSKWKFTNSPTFLEVLEEFPSLRVSAGFLLSQLPILKPRFYSISSSRDHTPTEIHLTVAVVTYHTRDGQGPLHHGVCSTWLNSLKPQDPVPCFVRNASGFHLPEDPSHPCILIGPGTGIAPFRSFWQQRLHDSQHKGVRGGRMTLVFGCRRPDEDHIYQEEMLEMAQKGVLHAVHTAYSRLPGKPKVYVQDILRQQLASEVLRVLHKEPGHLYVCGDVRMARDVAHTLKQLVAAKLKLNEEQVEDYFFQLKSQKRYHEDIFGAVFPYEAKKDRVAVQPSSLEMSAL
What is the function of this protein?
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body (PubMed:7531687, PubMed:7544004, PubMed:7682706, PubMed:7504305).  In macrophages, NO mediates tumoricidal and bactericidal actions.  Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2 (By similarity).  As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S-nitrosylation of GAPDH on 'Cys-247' implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM (PubMed:25417112).  Involved in inflammation, enhances the synthesis of pro-inflammatory mediators such as IL6 and IL8 (PubMed:19688109).
What are the official names of this protein?
Nitric oxide synthase, inducible, Hepatocyte NOS, HEP-NOS, Inducible NO synthase, Inducible NOS, iNOS, NOS type II, Peptidyl-cysteine S-nitrosylase NOS2.
What is the protein family that this protein belongs to?
Belongs to the NOS family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Note=Localizes as discrete foci scattered throughout the cytosol and in the presence of SPSB1 and SPSB4, exhibits a more diffuse cytosolic localization.
Protein: SYK_POLAQ
Sequence: MNDKTNPAPATEVVDENHIIAERREKLAKLRENGIAFPNDFVPTHLAVDLHAHYDSLTKEELAAKKIHVKVAGRMVLKRVMGKASFATIQDRSGQIQFYINDEISGADTHGAFKHWDMGDFISAEGNLFKTNKGELSVECSNLRLLSKSLRPLPDKFHGLSDLETKYRQRYVDLIVNPESRNTFKARSNAIASLRRHMLDADFMEVETPMLHPIPGGATAKPFITHHNALDMQMFLRIAPELYLKRLVVGGFERVFEINRNFRNEGVSPRHNPEFTMMEFYAAYTDYRWLMDFTEGLIRAAAVDAQGTAVLTHQGRELDLSKPFQRLTINEAILKYCAQSGKSYEAIQLDDADFIRAELKKGGENPDSPTLKNAGIGALQLALFELVAESHLWEPTYIIDYPIEVSPLARESDTRPGITERFELFITGREIANGFSELNDAEDQANRFRKQVEQKEAGDEEAMYFDHDFIRALEYGMPPTGGCGIGIDRLVMLLTDAPNIRDVILFPHLRREEE
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_BRUC2
Sequence: MSGLFITFEGGEGAGKSTQIALLASHLRNHGFDPVITREPGGSPGAEAIRHVILSGNAETYGPAMEALLFAAARADHVDQLIRPALAEGRIVLCDRFIDSGRAYQGVTGNLDATYMAAIERIAIDGAMPDLTLVLDICAERGLSRAGKRRGSDTADRFEKEDIAVHEARRQAFLEIARQEPARCKVIDADRSQEKIADEIRSVVDTILTEKGLL
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: PEPQ_SHESH
Sequence: MDQLTNHFHAHVAELNRRVAEIVARENLSGLVIHSGQPHRQFLDDMDYPFKVNPHFKAWLPILDNPHCWLLVNGRDKPQLIFYRPVDFWHKVADLPDEFWTAHVDIKLLTKADKVADLLPKDIVDWAYVGEHLDVAEVLGFKTRNPDAVMSYLHYHRATKTEYELACMRKSNEIAVKGHVAAKNAFYNGGSEFEIQQQYLMATNQGENEVPYGNIIALNRNASILHYTKLENQSPQPRRSFLIDAGANFFGYASDITRTYAFEKNIFSELIEAMDRAQLEIIDTMRPGVKYVDLHLATHQKVAQMLIDFDLATGDREGLIEQGITSVFFPHGLGHMLGLQVHDMGGFLHDERGTHIAAPDAHPFLRCTRTLAANQVLTIEPGLYIIDSLLQGLKQDNRQHQVNWNSVDLLRPFGGIRIEDNVIVHSDKNENMTRDLGLD
What is the function of this protein?
Splits dipeptides with a prolyl residue in the C-terminal position.
What are the official names of this protein?
Xaa-Pro dipeptidase, X-Pro dipeptidase, Imidodipeptidase, Proline dipeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
Protein: UHPT_SALTY
Sequence: MLAFLNQVRKPTLDLPLDVRRKMWFKPFMQSYLVVFIGYLTMYLIRKNFNIAQNDMISTYGLSMTELGMIGLGFSITYGVGKTLVSYYADGKNTKQFLPFMLILSAICMLGFSASMGAGSTSLFLMIAFYALSGFFQSTGGSCSYSTITKWTPRRKRGTFLGFWNISHNLGGAGAAGVALFGANYLFDGHVIGMFIFPSIIALIVGFIGLRFGSDSPESYGLGKAEELFGEEISEEDKETEENEMTKWQIFVEYVLKNKVIWLLCFSNIFLYVVRIGIDQWSTVYAFQELKLSKEVAIQGFTLFEVGALVGTLLWGWLSDLANGRRALVACVALALIIATLGVYQHASNQYVYLASLFALGFLVFGPQLLIGVAAVGFVPKKAIGAADGIKGTFAYLIGDSFAKLGLGMIADGTPVFGLTGWAGTFAALDAAAIGCICLMAMVAVMEERKIRREKKIQQVNIA
What is the function of this protein?
Mediates the exchange of external hexose 6-phosphate and internal inorganic phosphate.
What are the official names of this protein?
Hexose-6-phosphate:phosphate antiporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EFM7_GIBZE
Sequence: MSGEVDYGFGDLMDDPEDYCPPTPPPTSQVFTMQSGKPITLHLVGASPTEAHHLWNGAKMIADFFEEDLSRVKGKTVLELGAAAGLPSLVAAILGAHKVVVTDYPDPDIIRIMQKNVDECDETVEPRGRIVDTVDAMGFVWGADSVPLLARLNPTDDSHKERFDILILADLLFRHSEHGNMVKTIKETLKISRESVAYVFFTSYRPWKKELDMGFFDIAREQGFEVEQIAERRLDKPLFENDPGDLDVQKTVKGFAVRWSAEACN
What is the function of this protein?
S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono- and dimethylation of 'Lys-3'.
What are the official names of this protein?
Protein N-terminal and lysine N-methyltransferase EFM7, Elongation factor methyltransferase 7.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM7 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P2C48_ORYSJ
Sequence: MRHISSLLQGLARSLSVGKERKGGDGDDGKAAAATATAVLRTSGTLWGEGSETFAAVCSRRGEKGINQDCSIVCEGFGCEEGSVLCGIFDGHGQWGHYVAKAVRESLPPALLRRWREAVTLAALIDGGEKRLCECRPDLWRQSYLAACAAVDAELRASRRLDAVHSGCTALSLVKHGDLLVVANVGDSRAVLATASPDDGGGARLAAVQLTVDFKPNLPQERERIMECNGRVQCLADEPGVHRVWRPDREGPGLAMSRAFGDYCVKDYGVISAPEVTHRRITAQDHFVILATDGVWDVVSNEEAVQIVASAPEREKAAKRLVEFAVRAWRRKRRGIAVDDCSAICLFFHSPPS
What are the official names of this protein?
Probable protein phosphatase 2C 48, OsPP2C48.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: 86A22_PETHY
Sequence: MEVSTTMMIVAIVAAYLLWFKSITKSMKGPKGPTMWPVVGSLPGLIENGNRMHEWIADNLRACSGTYQTCICAIPFLARKQLVTVTCDPKNLEHILKVRFDNYPKGPTWQAVFHDLLGEGIFNSDGDTWLFQRKTAALEFTTRTLRQAMGRWVNRAIKNRFCPILEMAQVQGKPVDLQDLLLRLTFDNICGLAFGKDPETLSPELPENNFATSFDRATEATLHRFIMPEFVWKLKKMLGLGLEVSLNNSLKQVDNYMTDVINTRKLELLNHQNGGPQHDDLLSRFMKKKESYSDKFLQHVALNFILAGRDTSSVALSWFFWLVSSNPRVEEKILVEICTILAETRGNDTSKWLEEPLVFEEVDQLMYLKAALSETLRLYPSVPEDSKHVISDDYLPDGTFVPAGSNITYSIYSTGRMKFIWGEDCLEFKPERWMSQDGDKFQVQDTFRFVAFNAGPRICLGKDLAYLQMKSIAAAVLLRHRLAVAPGHKVEQKMSLTLFMKDGLVMNVTPRDLTPILAKIEKFGKVESCAGEHHLINNGIHQPGSIAVNGIAA
What is the function of this protein?
Fatty acyl-CoA omega-hydroxylase essential for the production of omega-hydroxy fatty acids and the biosynthesis of triacylglycerol-/diacylglycerol-based estolide polyesters in the stigma.  Substrate preference is 16:0-CoA > 18:1-CoA > 18:0-CoA.
What are the official names of this protein?
Cytochrome P450 86A22, Long-chain acyl-CoA omega-monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RS12_WOLWR
Sequence: MPTINQLIRKGRLGLTHKKKVPALGKSNPQRRGVCTKVYTTTPRKPNSALRKVARVKISGYGEVTAYIPGEGHNLQEHSVVLIRGGRVKDLPGVRYHIIRGALDLRGVQNRKKARSKYGVKKSG
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: ZAPA_LYSSC
Sequence: MEKQEKNKISVEIYGHTYKMVGLESIGHMRLVASIVDDRMREMNVHNPSLDSTKLAVLTAVNTVHDNLLLKERLEQLEEELKKLKG
What is the function of this protein?
Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring.  It is recruited early at mid-cell but it is not essential for cell division.
What are the official names of this protein?
Cell division protein ZapA, Z ring-associated protein ZapA.
What is the protein family that this protein belongs to?
Belongs to the ZapA family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes at mid-cell. In sporulating cells, localizes near the cell poles.
Protein: WDFY2_MOUSE
Sequence: MAAEIQPQPLTRKPILLQRVEGSQEVVNMAVIVPKEEGVISVSEDRTVRVWLKRDSGQYWPSIYHAMPSPCSCMSFNPETRRLSIGLDNGTISEFILSEDYNKMTPVKNYQAHQSRVTMVLFVLELEWVLSTGQDKQFAWHCSESGQRLGGYRTSAVASGLQFDVETRHVFIGDHSGQVTILKLEQENCTLLTSFRGHTGGVTALCWDPVQRVLFSGSSDHSVIMWDIGGRKGTAIELQGHNDKVQALSYAQHTRQLISCGGDGGIVVWNMDVERQETPEWLDSDSCQKCDQPFFWNFKQMWDSKKIGLRQHHCRKCGKAVCGKCSSKRSSIPLMGFEFEVRVCDSCHEAITDEERAPTATFHDSKHNIVHVHFDATRGWLLTSGTDKVIKLWDMTPVVS
What is the function of this protein?
Acts in an adapter protein-like fashion to mediate the interaction between the kinase PRKCZ and its substrate VAMP2 and increases the PRKCZ-dependent phosphorylation of VAMP2 (By similarity).  Positively regulates adipocyte differentiation, by facilitating the phosphorylation and thus inactivation of the anti-adipogenetic transcription factor FOXO1 by the kinase AKT1 (PubMed:18388859).  Plays a role in endosomal control of AKT2 signaling; required for insulin-stimulated AKT2 phosphorylation and glucose uptake and insulin-stimulated phosphorylation of AKT2 substrates (PubMed:20189988).  Participates in transferrin receptor endocytosis (By similarity).
What are the official names of this protein?
WD repeat and FYVE domain-containing protein 2, Propeller-FYVE protein, Prof, WD40- and FYVE domain-containing protein 2.
What are the subcellular locations of this protein?
Endosome. Early endosome. Cytoplasm. Note=Localizes to intracellular vesicles. Colocalizes with VAMP2 and PRKCZ in intracellular vesicles (By similarity). Colocalizes with AKT2 in early endosomes (PubMed:20189988).
Protein: KBTB1_CAMPS
Sequence: MNNSSELIAVINGFRNSGRFCDIDIVINDERINAHRLILSGASEYFSILFSSDFIDSNKYEVNLSHLDYQSVNDLIDYIYGIPLSLTNDIVKYILSTADFLQIGSAITECENYILKNLCSRNCIDFYIYADKYNNKKIETASFNTILLNILRLINDENFKYLTEESMIKFLSDDMLNIKNEDFAPLILIKWLESTQQPCTVELLRCLRISLLSPQVIKSLYSHRLVGSIYECITFLNNISFLDESFPRYHSIELISIGISNSHDKISINCYNRKKNTWDIISSRRYRCSFAVAVLDNIIYMMGGYDQSPYRSSKVIAYNTCTNSWIYDIPELKYPRSNCGGVADDEYIYCIGGIRDQDSSLISSIDRWKPSKPYWQTYAKIREPKCDMGVAMLNGLIYVIGGVVKGDTCTDTLESLSQDGWMMHQRLPIKMSNMSTIVHAGKIYISGGYNNSSVVNGISNLVLSYNPIYDEWTKLSSLNIPRINPALWSVHNKLYVGGGISDDIQTNTSETYDKEKDCWTLDNGHMLPRNYIMYKCEPIKHKYPLEKTQYTNDFLKYLESFIGS
What is the function of this protein?
Probable substrate-specific adapter of CUL3-containing E3 ubiquitin-protein ligases which mediate the ubiquitination and subsequent proteasomal degradation of host target proteins.
What are the official names of this protein?
Kelch repeat and BTB domain-containing protein 1.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: UGPC_SALTY
Sequence: MAGLKLQAVTKSWDGKTQVIQPLTLDVADGEFIVMVGPSGCGKSTLLRMVAGLERVTSGDIWIDRKRVTEMEPKDRGIAMVFQNYALYPHMSVEENMAWGLKIRGMSKAHIEERVREAARILELDGLLKRRPRELSGGQRQRVAMGRAIVREPAVFLFDEPLSNLDAKLRVQMRLELQHLHRRLRTTSLYVTHDQVEAMTLAQRVMVMNKGVAEQIGTPVEVYEKPASRFVASFIGSPAMNLLDGVISASGDRFELPGGLALPIGADYRGHAGRNMTLGIRPEHIALSSQAEGGVPLTVDTLEILGADNLAHGRWGDQKLVVRLAHQQRPAAGSTLWLHLPEHQRHLFDGETGQRV
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
sn-glycerol-3-phosphate import ATP-binding protein UgpC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. sn-glycerol-3-phosphate importer (TC 3.A.1.1.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y462_MYCPN
Sequence: MFGLKVKDATVDSSKQSTESLKGEESSSSSTTSSTSTTQRGGSSGDTKVKALQVAVKKKSDSEDNGQIELETNNLANAPIKRGSNNNQQVQLKADDFGTSPSSSESGQSGTPTPWTPWLATEQIHKDLPKWSASILILYDAPYARNRTAIDRVDHLDPKVMTANYPPSWRTPKWNHHGLWDWKARDVLVQTTGFFNPRRHPDWFDQGQAVAENTQTGFDTDDTDNKKQGFRKQGEQSPAPIALPFEAYFANIGNLTWFGQALLVFGICLS
What are the official names of this protein?
Uncharacterized protein MPN_462.
What is the protein family that this protein belongs to?
Belongs to the adhesin P1 family.
Protein: Y473_BUCAI
Sequence: MTLEKIKKYLISKINIKFIEIYDDSQFHHYSKKGLTHLRIIIISDDFINQTLINRHRIIFSMLSKMIEKKIYSLTLNTYTLNEWKDKKLKKTSNVKCVKKNNIL
What are the official names of this protein?
Uncharacterized protein BU473.
What is the protein family that this protein belongs to?
Belongs to the BolA/IbaG family.
Protein: RPOA_ALISL
Sequence: MQGSVTEFLKPRLVDIEQVSLTHAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIEGVLHEYSTKEGVQEDILEILLNLKGLAVKVEGKDEVIITLNKSGAGPVVAGDITHDGDVEIANPEHVICHLTDDNAEISMRIKVERGRGYVPSTARIHTEEDERPIGRLLVDATYSPVDKISYAVEAARVEQRTDLDKLVIDMETNGTLDPEEAIRRAATILAEQLDAFVDLRDVRVPEEKEEKPEFDPILLRPVDDLELTVRSANCLKAEAIHYIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLENWPPASIAED
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: MQO2_STAAM
Sequence: MAKSNSKDIVLIGAGVLSTTFGSMLKEIEPDWNIHVYERLDRPAIESSNERNNAGTGHAALCELNYTVLQPDGSIDIEKAKVINEEFEISKQFWGHLVKSGSIENPREFINPLPHISYVRGKNNVKFLKDRYEAMKAFPMFDNIEYTEDIEVMKKWIPLMMKGREDNPGIMAASKIDEGTDVNFGELTRKMAKSIEAHPNATVQFNHEVVDFEQLSNGQWEVTVKNRLTGEKFKQVTDYVFIGAGGGAIPLLQKTGIPESKHLGGFPISGQFLACTNPQVIEQHDAKVYGKEPPGTPPMTVPHLDTRYIDGQRTLLFGPFANVGPKFLKNGSNLDLFKSVKTYNITTLLAAAVKNLPLIKYSFDQVIMTKEGCMNHLRTFYPEARNEDWQLYTAGKRVQVIKDTPEHGKGFIQFGTEVVNSQDHTVIALLGESPGASTSVSVALEVLERNFPEYKTEWAPKIKKMIPSYGESLIEDEKLMRKIRKQTSKDLELGYYEN
What are the official names of this protein?
Probable malate:quinone oxidoreductase 2, MQO 2, Malate dehydrogenase [quinone] 2.
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: DFAX2_BETVU
Sequence: ATCRKPSMYFSGACFSDTNCQKACNREDWPNGKCLVGFKCECQRPC
What is the function of this protein?
Strong inhibiting activity against C. beticola and other filamentous fungi.  Little or no effect against bacteria.
What are the official names of this protein?
Defensin-like protein AX2, Antifungal protein AX2.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
Protein: DHPS_STAAC
Sequence: MTKTKIMGILNVTPDSFSDGGKFNNVESAINRVKAMIDEGADIIDVGGVSMRPGHEMVSLEEEMNRVLPVVEAIVGFDVKISVDTFRSEVAEACLKLGVDMINDQWAGLYDHRMFQIVAKYDAEIILMHNGNGNRDEPVVEEMLTSLLAQAHQAKIAGIPSNKIWLDPGIGFAKTRNEEAEVMARLDELVATEYPVLLATSRKRFTKKMMGYDTTPVERDEVTAATTAYGIMKGVRAVRVHNVELNAKLAKGIDFLKENENARHNLS
What is the function of this protein?
Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
What are the official names of this protein?
Dihydropteroate synthase, DHPS, Dihydropteroate pyrophosphorylase.
What is the protein family that this protein belongs to?
Belongs to the DHPS family.
Protein: RFA1_SCHPO
Sequence: MAERLSVGALRIINTSDASSFPPNPILQVLTVKELNSNPTSGAPKRYRVVLSDSINYAQSMLSTQLNHLVAENKLQKGAFVQLTQFTVNVMKERKILIVLGLNVLTELGVMDKIGNPAGLETVDALRQQQNEQNNASAPRTGISTSTNSFYGNNAAATAPAPPPMMKKPAAPNSLSTIIYPIEGLSPYQNKWTIRARVTNKSEVKHWHNQRGEGKLFSVNLLDESGEIRATGFNDQVDAFYDILQEGSVYYISRCRVNIAKKQYTNVQNEYELMFERDTEIRKAEDQTAVPVAKFSFVSLQEVGDVAKDAVIDVIGVLQNVGPVQQITSRATSRGFDKRDITIVDQTGYEMRVTLWGKTAIEFSVSEESILAFKGVKVNDFQGRSLSMLTSSTMSVDPDIQESHLLKGWYDGQGRGQEFAKHSVISSTLSTTGRSAERKNIAEVQAEHLGMSETPDYFSLKGTIVYIRKKNVSYPACPAADCNKKVFDQGGSWRCEKCNKEYDAPQYRYIITIAVGDHTGQLWLNVFDDVGKLIMHKTADELNDLQENDENAFMNCMAEACYMPYIFQCRAKQDNFKGEMRVRYTVMSINQMDWKEESKRLINFIESAQ
What is the function of this protein?
As part of the replication protein A (RPA/RP-A), a single-stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair.  Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
What are the official names of this protein?
Replication factor A protein 1, Single-stranded DNA-binding protein p68 subunit.
What is the protein family that this protein belongs to?
Belongs to the replication factor A protein 1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLO2_SHEAM
Sequence: MLDIRPIPAFADNYIWMIVLPDGGAVVVDPGDAMPVINTLQRLNLQLTAVLLTHHHRDHNGGINQLRDWAKSNGQSFTVYGAVTSDYSDVLCRDGDTVDISGLTSPVRVLSVPGHTLDHLAFVVDNALFCGDTLFSGGCGRLFEGDAGQLYDSLAKLASLPDDTLVYCAHEYTLSNLRFALAVEPQNQCLQDYVKQVNNLREANKPSLPSTLGTEKAINPFLRVDTATVHAAVAAQAGQKVPDEVTCLALLRRWKDNF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: LKHA4_NEOFI
Sequence: MPTVVNPPRDPNTLSNYNNWVSTHITANFDILFDQRKLAGSVIHQFRSTTHGESNHIILDTNHLDIGSVKVNGQPSEWEYLPRLEPYGTPLKIKLDQGVKLNEMIEVDISVKTTEKCTALQWLTPAQTSNKKHPYMFSQCQAIHARSIFPCQDTPDVKCTLDFNITSPLPVIASGLPVRGSSEAPKSDGKTLYKFHQKVPIPSYLFALASGDISEAPIGPRSVVATSPDKLGECQWELEADTEKFINAIEKIVYPYVWGEYNVLILPPSFPYGGMENPIFTFATPSIISKDRENIDVIAHELAHSWSGNLVTNASWEHFWLNEGWTTYLERRIVAAVHGEPYRHFSAIIGWKALTDSVEHFGPEHDFTKLITNLKGMDPDDAFSSIPYEKGFNFLFHLENLVGKSKFDLFIPHYFNKYKGKSLDSYEFKSTILDFFKDDSEASTALNELDWDSWFYAPGLPPKPDFDTSLVDVVYDLAKKWLSLPNSSFKPQPEDIRGLTANQVVVFLEQILVSERQLTPELSKLMGEIYGLAASQNIEVANLYFQVGLQAGDASVLEPTADLLGKIGRMKFVRPLYRKLAKFDRKRAVETFEKHRDFYHPICRAMVEKDLFGKKDE
What is the function of this protein?
Aminopeptidase that preferentially cleaves di- and tripeptides.  Also has low epoxide hydrolase activity (in vitro).  Can hydrolyze the epoxide leukotriene LTA(4) but it forms preferentially 5,6-dihydroxy-7,9,11,14-eicosatetraenoic acid rather than the cytokine leukotriene B(4) as the product compared to the homologous mammalian enzyme (in vitro).
What are the official names of this protein?
Leucine aminopeptidase 2, Epoxide hydrolase, Leukotriene A-4 hydrolase homolog, LTA-4 hydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: AADH2_MAIZE
Sequence: MAPPQTIPRRGLFIGGAWREPCLGRRLPVVNPATEATIGDIPAGTAEDVEIAVAAARDAFSRDGGRHWSRAPGAVRANFLRAIAAKIKDRKSELALLETLDSGKPLDEASGDMDDVAACFEYYADLAEALDGKQQSPISLPMENFKSYVLKEPIGVVGLITPWNYPLLMATWKVAPALAAGCTTILKPSELASVSCLELGAICMEIGLPPGVLNIITGLGPEAGAPLSSHSHVDKVAFTGSTETGKRIMISAAQMVKPVSLELGGKSPLIVFDDIGDIDKAVEWTMFGIFANAGQVCSATSRLLLHEKIAKKFLDRLVAWAKNIKVSDPLEEGCRLGSVISEGQYEKIKKFISTARSEGATILYGGGRPQHLRRGFFLEPTIITDVSTSMQIWQEEVFGPVICVKEFRTESEAVELANDTHYGLAGAVISNDQERCERISKALHSGIIWINCSQPCFVQAPWGGNKRSGFGRELGEWGLDNYLTVKQVTKYCSDEPWGWYQPPSKL
What is the function of this protein?
Dehydrogenase that catalyzes the oxidation of several aminoaldehydes (PubMed:23408433).  Metabolizes and detoxifies aldehyde products of polyamine degradation to non-toxic amino acids (Probable).  Catalyzes the oxidation of 4-aminobutanal and 3-aminopropanal to 4-aminobutanoate and beta-alanine, respectively (PubMed:23408433).  Catalyzes the oxidation of 4-(trimethylamino)butanal and 4-guanidinobutanal to 4-trimethylammoniobutanoate and 4-guanidinobutanoate, respectively (PubMed:23408433).
What are the official names of this protein?
Aminoaldehyde dehydrogenase 2, ZmAMADH2, 4-trimethylammoniobutyraldehyde dehydrogenase AMADH2, Aminobutyraldehyde dehydrogenase AMADH2, Gamma-guanidinobutyraldehyde dehydrogenase AMADH2.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.