PharMolix/UniProtQA huggingface dataset:
Protein: M1I1L_DANRE
Sequence: MMQLSNDSHCNKHSLLNVMNRFIAAANNMDETIMVPNLLRDVPLEDQESHASVSHNNNNNNEPSFPNKQRDMYEHYLLLKSIKNDMEWGLLKREMAGGASFLEMAVKQEELPQMKGEAVEEGPDLEGQFHYHLHGLFSVLSKLTVQADHLTNRYKREIGGGSLLR
What is the function of this protein?
Involved in stabilization of microtubules.  May play a role in the regulation of lipogenesis (By similarity).
What are the official names of this protein?
Mid1-interacting protein 1-like, Gastrulation-specific protein G12-like.
What is the protein family that this protein belongs to?
Belongs to the SPOT14 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton. Note=Associated with microtubules.
Protein: GPDA_CORJK
Sequence: MVQVAVMGAGSWGTTVAKVFADAGNEVRLWARRAEVAEDVRDNHRNSAYLGDIELPAALTGTTDPAEALNGAEIVVLGVPSQSLRENLQNWKDLIGPDASLVSLAKGIEHSSGLRMSQLVSEVADVPSERVAVLTGPNLAREVAQGQPAATVVACTDMDRAKLIQAAVAAPYFRPYTNTDVIGCEIAGTCKNVIALAAGIAAGMGFGDNTAATVITRGLAETTRLALEVGADARTLSGLAGMGDLVATCTSTLSRNRRFGEHLGKGETLEQAAASTKGQVAEGVVSSQSVFELAEKVGVETPITEAVVGVCHEGADVQQIMMGLLGRSKKAE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DADA_NEIMB
Sequence: MKVLVLGAGVAGVSSAWYLAEAGHEVTVIDRAEGVAMETSFANAGQLSYGYTTPWAAPGIPTKALKWLFKSHPPLLFRPDGSLYQIEWLWQMLQNCTAAHYQTNKERMVRISEYSREMFRRFEAQTGMNFEGRKKGTLQIFRQTKEVEAAKQDIAVLERYGVPYRRLKPEECAEFEPALARVTAKIAGGLHLPADATGDCRLFTENLYKLCQEKGVRFHFNQNISRIDHNGLRIKTVETETGRFEADAVVCALGCFSRTVLAQLDLNLPIYPVKGYSLTLPVTNSDGAPVSTVLDESYKVAITRFDNRIRVGGMAELSGYEIKLPEKRRETLALVVNDLFPEGGDLSQASFWSGLRPMTPDSTPLIGRTRFDNLFLNTGHGTLGWTMSLGSAKLTADIVSGKDTEIRSDDLSLSRYQA
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: ENO_FRAT1
Sequence: MSSQIKQVFARQILDSRGNPTIEVEVVLESGAFGRAAVPSGASTGIREALELRDGNKALFLGKSVYKAVENVNTKIAQAVKGLDALDQRLIDKTMIELDGSENKKNLGANAILGVSLATARAAASHLRKPFYRYLMDVKEYLMPVPMMNVINGGSHADNNVDMQEFMIVPAGFDTFSEALRCGTEVFHILKKVLIADGYSVAGVGDEGGYAPDLPSNEAAIEAILKAVKEAGYEPGKHVFIALDPASSEFYKDGKYELKSENKSLTSEEMIDYYAAWVEKYPIVSIEDGLAEEDWAGWKLLTEKLGNKVQLVGDDLFVTNPSILAKGIEKGIANSILIKLNQIGTLTETFEAMAMAGQAGYTCVVSHRSGETSDTIIADLAVATCSGQIKTGSLSRSDRIAKYNQLLRIEEELGENAIYPGIKAFVFNSDEEVEEVVQEIIVEDSEAEKVVVQVEE
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: MURC_SHESW
Sequence: MTKTERYIQLRSMIPEMRRIKRIHFVGIGGAGMGGIAEVLVNEGYQVSGSDIAQNTVTDRLCLLGAKIQIGHAADNVQQVDVVVVSTAINAENPEIIAAKELRIPIVRRAEMLAELMRYRHGVAIAGTHGKTTTTSLIASVYGQAGRDPTFVIGGLLNSAGTNARLGTSRYLIAEADESDASFLHLQPMVSVVTNIEADHMDTYGGDFEKLKSTFVDFLHNLPFYGVAVVCIDDPVVREIMPRIGRHLVTYGFSDDADVQALNFSQQGHQCRFTVRRKGKEDLDLLLNLPGQHNVLNALAAIAVATEDEIDDSALIQALAEFQGIGRRFQHLGKFATPKGEVMLVDDYGHHPSEVAATIKAARAGWPEKRLVMAYQPHRYTRTRDLYEDFIEVLSQVDCLLLLDVYSAGEAPITGADGRALCRSIRLRGQLDPIFIASPDQLAEVLPDVLQEGDLLLTQGAGNIGALSRQLAVTELGFAKVEIAQVPA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIPC_BURP1
Sequence: MSIGVQSSGINISHAELSRLVDAGKSEQGDKAVRDGGRALARADAALAAVVGERVAARRDAVAGSGAQRVELARPKPDAQTRATDRRTVSGLEREHKRLAASQTPRVTGMHDALVQRHVSLDGAKAAHGEGVKRAAGDAPRAAADAPQRFAFADDKAFDAMLALGAAMQKNVQSDLAMQGKLTMLAHDAMMSAAAQDRSIGAAQMTAAIAGGALQATTSLGGAMQQMKSLSTKSMSIEKELKPQAELKQFHAEQALELRGINKPVLSNDEVSHVKIKRDTGETVRHEIDHGGERMSDEHASVLAQEAPARQHRIDMHGMRHEENLVKAGRQQMKGDLLQSGGQIGKNQIDGASAQQQGADRAEQKEDENAQQTAMAAASTRDEAAHRSREAAQKAIDAAKSQVANDNAVAAQVAGNLRT
What are the official names of this protein?
Effector protein BipC.
What is the protein family that this protein belongs to?
Belongs to the invasin protein C family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the bsa type III secretion system.
Protein: SSTT_PSEE4
Sequence: MTPVLRLINRTGLVTQICIGLLAGIALALFAPAVARDLAFLGKVFVTALKAVAPVLVFILVMASIANHRHGQETHIRPILWLYLLGTFAAAVVAVAASMLFPSSLVLSTSEASLSAPGGIGEVLQNLLLSAVDNPINALLNANFIGILTWAIGLGVALRHASDTTRGVVEDLSNGVTLIVRVVIRFAPLGIFGLVSATLAQSGLDALLGYLHLLAVLIGCMLFVALVMNPLIVFWKIRRNPYPLVLMCLRESGITAFFTRSSAANIPVNLALSQKLGLHEDTYSVSIPLGATINMAGAAITITVLTLAAVHTLGIPVDLPTAVLLSVVAAICACGASGVAGGSLLLIPLACSLFGIPSEIAMQVVAVGFIIGVLQDSAETALNSSTDVLFTAAACQAMEQRSA
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ARP4_CANAL
Sequence: MATASTTTVYGGDEINAIVLDPGSYTTRIGYAGDDFPKVITSSYYGQVKNDKKKIFGESINVPRANYDIKPILKESIIVDWDAAIEQYQYYFDQQLKVVGPEQPILITEPIWTETSYRQQLVETFFENFEFSGIYLAKSPTCVSFQQGRSNCLVVDLGHDSVSVTPVIDGICLLKSSMKTNYGGKFLSNEIQDYLIDTKKVVMEPSFKIKSKIPTTYPDPPKYELKNNNTIPTSSSSSLSQSFLEFQNEKIYHNFKEILEVPEKNSSSGTTTTTTTTNKDSSRLFELPTGQSIVIDRFKIAESIFDPTIYKFTNSKLSFPPNNGEISITQANEYRPLKRVRKNDDEEEDSNQSTPKPEVNIRGISQLISHTLSNIDIDLRASLANNIIVTGGVSLISQLTERLYLELSNNNPGLKIRLHAVGNSTERINQAWIGGSVLASLGTFHQMWVTKEEYNEVGVDRILNQRFR
What is the function of this protein?
Chromatin interaction component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A.  The NuA4 complex is also involved in DNA repair.  Is required for NuA4 complex integrity.  Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling.  Component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair (By similarity).
What are the official names of this protein?
Actin-related protein 4, Actin-like protein ARP4, Actin-like protein 4.
What is the protein family that this protein belongs to?
Belongs to the actin family. ARP4 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CHM4C_XENLA
Sequence: MSKITKLFKSSGGSGSSSKNRKGPSAQEALFKLRETEEMLTKKQEYLEKKIELELATAKKHGTKNKRAALQALKKKKRLEKQLAQIDGTLSTIEFQREALENSHTNTEVLKNMGYAAKAMKAAHENMDLEKIDDLMQDIHEQQDVAQEISDAISRPVGFGDEFDEDELLEELEELEQEDLNSQMANVNLPSVPSSKLPSTKLPSRPASSRKKVEDDDDMQMLAAWAT
What is the function of this protein?
Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs.  MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids.  Key component of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage (By similarity).
What are the official names of this protein?
Charged multivesicular body protein 4c, Chromatin-modifying protein 4c, CHMP4c.
What is the protein family that this protein belongs to?
Belongs to the SNF7 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Late endosome membrane; Peripheral membrane protein.
Protein: RS14Z_BIFLO
Sequence: MAKTALKNKAAGKPKFKVRAYTRCQVCGRPHSVYRKFGLCRICLREKAHRGELPGVTKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: KDSA_PSEAE
Sequence: MAQKIVRVGDIQIGNDLPFVLFGGMNVLESRDLAMQVCEEYVRVTEKLGIPYVFKASFDKANRSSIHSFRGPGLEEGMKIFEEIKKTFKVPVITDVHEPFQAQPVAEVCDIIQLPAFLSRQTDLVVAMARTNAVINIKKAQFLAPQEMKHILTKCEEAGNDRLILCERGSSFGYNNLVVDMLGFGIMKQFEYPVFFDVTHALQMPGGRADSAGGRRAQVTDLAKAGLSQKLAGLFLEAHPDPEHAKCDGPCALRLNKLEAFLSQLKQLDELIKSFPAIETA
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIM2_STRP4
Sequence: MQEFTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADDPREVLDFTKQSQALFINLGHLSAEKEKAIRIAASYAAQVCLPMVVDAVGVTASSIRKSLVRDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYHGMSFLVTGPKDLVVSKNQVAVLGNGCAELDWITGTGDLVGALTAVFLSQGKTGFEASCLAVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase 2, 4-methyl-5-beta-hydroxyethylthiazole kinase 2, TH kinase 2, Thz kinase 2.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: SK1_MASDA
Sequence: EQFDDYGHMRF
What is the function of this protein?
Myotropic peptide.
What are the official names of this protein?
Sulfakinin-1, MasDa-SK-1.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: LEF10_NPVAC
Sequence: MTNVWFATDVNLINCVLKDNLFLIDNNYIILNVFDQETDQVRPLCLGEINALQTDAAAQADAMLDTSSTSELQSNAST
What is the function of this protein?
Plays an essential role in viral DNA replication.
What are the official names of this protein?
Late expression factor 10.
What is the protein family that this protein belongs to?
Belongs to the baculoviridae LEF-10 family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: GLMM2_SHEFN
Sequence: MSRKYFGTDGVRGRVGTFPITPDFAMKLGWAAGKVLASTGTQEVLIGKDTRSSGYMLESAIEAGLSAAGVNVALIGPMPTPAVAYLASTFRADAGVVISASHNPFYDNGIKFFSNSGTKLNDQQELEIEALLDQALNHNAMECVSSELLGKVRRITDAAGRYIEFCKGVFAKDLTLAGLKIVVDSANGAAYHIAPNVYRELGAEVISINDKPNGTNINDHCGATHLDSLQTAVMVHEADLGIAMDGDADRVMFVDHNGHVVDGDQILYILAKSAKQQGTMTGGVVGTLMSNLGLEIALKEMDIPFKRAKVGDRYVVEQLKQTGWRIGGEGSGHILHLDHASTGDAVVASLLVLQAVLQSGQSLAEIVSCMKKLPQVLLNVRLTANNADEILASAAVKQAVIEAEAVLAENGRVLLRKSGTEPLIRVMVESTDPEMSQAQAEHIAKVVTSF
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase 2.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: HSLU_BARBK
Sequence: MCVVFSPREIVSELDRFIIGQKDAKRSVAIALRNRWRRQQLEGQIREEVMPKNILMIGPTGVGKTEIARRLAKLAGAPFVKVEATKFTEVGYVGRDVEQIIRDLVEIAISLVREKKRDEVQERAHINAEERVLEALVGKTASPATRDNFRQKLRAGELDDKEIEIEVANNSNNSAPTFDIPGMPGAQMGIMNLSDIFGKIGGRTKIRKTTVKDAFKPLIDDESEKLLDQDQIIQEALCITENDGIVFIDEIDKIATQDGGAGAAISREGVQRDLLPLVEGTIVATKYGQIKTDHILFIASGAFHVSKPSDLLPELQGRLPIRVELNALTKEDLRRILTEPEASLIKQYIALMATEDVHLEITDDAIDTLADIAVDLNARIENIGARRLQTVMERVLDEISFTAPDKAGTSFKVDATYVRQSVGELASDVDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: K2C7_XENLA
Sequence: MAFNSRQSSFSTRSAVPNAGFSQMRISSTRSSSGGSGLGREGGNFSSSSLSNLGSVKRSVSYGVSSGRSGGAGFGGAGFGGAGYGGSGFGGGVAYSGPGIQEVTINQSLLSPLNLEIDPTIQTVRQEEREQIKTLNNKFASFIDKVRFLEQQNRVLETKWELLQNQKSAKASNIGPLFEAYIANLRRQLESLTNDKGKLEGELRNMQDLVEDFKNKYEDEINKRTGAENEFVVLKKDVDAAYMNKVELESKMEGLTDEINFLRALYEAELRELQEQISDTSVVLSMDNNRALDMDSIIAEVKAQYEDIANKSRANAESAYQSKFQELQAAAGRHGDDLRSTKTEISELNRAMQRLQAEIESVKAQRAKLEAQIAEAEERGELALKDARSKLAELEAALQKAKQDMARQLREYQELMNVKLALDIEIATYRKLLEGEENRITEGPGPVSVSVVNSTSSSMGGGSSSGFGSGYSGGSSYGAGGFGNSSARFGSGGSSGVKSYSVTTTSSSRSFRQ
What is the function of this protein?
Blocks interferon-dependent interphase and stimulates DNA synthesis in cells.
What are the official names of this protein?
Keratin, type II cytoskeletal 7, XENCK55(5/6).
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOAA_XANAC
Sequence: MTAPMQDRYGRPLRDLRLSVIEACNFRCGYCMPADRVPDDYGFDSQQRLSFDQLETLVRAFVSVGVTKVRLTGGEPLLRRDLPSLIARLTAIEGIEDLALTTNGTLLARQAVALRQAGLRRITVSMDALEPALFRRMSGDRGEIAQVLTGIAAAEQAGFQRLKINCVVQRGVNEDQVLPLVEHFRGTGHVLRFIEFMDVGSCNGWTPDAVVTSAQLHERIHARWPLVALDANYTGEVAQRHAFADGAGEVGFVSSVSVPFCGDCQRARVSADGHLYTCLFASQGHDLKPALANGEPALATHLRQRWSVRGDRYSEVRASVPRRGKPVEMFLIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: PHAS_MYCBO
Sequence: MGLGSAASGTGADRGAWTLAEPRVTPVAVIGMACRLPGGIDSPELLWKALLRGDDLITEVPPDRWDCDEFYDPQPGVPGRTVCKWGGFLDNPADFDCEFFGIGEREAIAIDPQQRLLLETSWEAMEHAGLTQQTLAGSATGVFAGVTHGDYTMVAADAKQLEEPYGYLGNSFSMASGRVAYAMRLHGPAITVDTACSSGLTAVHMACRSLHEGESDVALAGGVALMLEPRKAAAGSALGMLSPTGRCRAFDVAADGFVSGEGCAVVVLKRLPDALADGDRILAVIRGTSANQDGHTVNIATPSQPAQVAAYRAALAAGGVDAATVGMVEAHGPGTPIGDPIEYASVSEVYGVDGPCALASVKTNFGHTQSTAGVLGLIKVVLALKHGVVPRNLHFTRLPDEIAGITTNLFVPEVTTPWPTNGRQVPRRAAVSSYGFSGTNVHAVVEQAPQTEAQPHAASTPPTGTPALFTLSASSADALRQTAQRLTDWIQQHADSLVLSDLAYTLARRRTHRSVRTAVIASSVDELIAGLGEVADGDTVYQPAVGQDDRGPVWLFSGQGSQWAAMGADLLTNESVFAATVAELEPLIAAESGFSVTEAMTAPETVTGIDRVQPTIFAMQVALAATMAAYGVRPGAVIGHSMGESAAAVVAGVLSAEDGVRVICRRSKLMATIAGSAAMASVELPALAVQSELTALGIDDVVVAVVTAPQSTVIAGGTESVRKLVDIWERRDVLARAVAVDVASHSPQVDPILDELIAALADLNPKAPEIPYYSATLFDPREAPACDARYWADNLRHTVRFSAAVRSALDDGYRVFAELSPHPLLTHAVDQIAGSVGMPVAALAGMRREQPLPLGLRRLLTDLHNAGAAVDFSVLCPQGRLVDAPLPAWSHRFLFYDREGVDNRSPGGSTVAVHPLLGAHVRLPEEPERHAWQADVGTATLPWLGDHRIHNVAALPGAAYCEMALSAARAVLGEQSEVRDMRFEAMLLLDDQTPVSTVATVTSPGVVDFAVEALQEGVGHHLRRASAVLQQVSGECEPPAYDMASLLEAHPCRVDGEDLRRQFDKHGVQYGPAFTGLAVAYVAEDATATMLAEVALPGSIRSQQGLYAIHPALLDACFQSVGAHPDSQSVGSGLLVPLGVRRVRAYAPVRTARYCYTRVTKVELVGVEADIDVLDAHGTVLLAVCGLRIGTGVSERDKHNRVLNERLLTIEWHQRELPEMDPSGAGKWLLISDCAASDVTATRLADAFREHSAACTTMRWPLHDDQLAAADQLRDQVGSDEFSGVVVLTGSNTGTPHQGSADRGAEYVRRLVGIARELSDLPGAVPRMYVVTRGAQRVLADDCVNLEQGGLRGLLRTIGAEHPHLRATQIDVDEQTGVEQLARQLLATSEEDETAWRDNEWYVARLCPTPLRPQERRTIVADHQQSGMRLQIRTPGDMQTIELAAFHRVPPGPGQIEVAVRASSVNFADVLIAFGRYPSFEGHLPQLGTDFAGVVTAVGPGVTDHKVGDHVGGMSPNGCWGTFVTCDARLAATLPPGLGDAQAAAVTTAHATAWYGLHELARIRAGDTVLIHSGTGGVGQAAIAIARAAGAEIFATAGTPQRRELLRNMGIEHVYDSRSIEFAEQIRRDTNGRGVDVVLNSVTGAAQLAGLKLLAFRGRFVEIGKRDIYGDTKLGLFPFRRNLSFYAVDLGLLSATHPEELRDLLGTVYRLTAAGELPMPQSTHYPLVEAATAIRVMGNAEHTGKLVLHIPQTGKSLVTLPPEQAQVFRPDGSYIITGGLGGLGLFLAEKMAAAGCGRIVLNSRTQPTQKMRETIEAIAAMGSEVVVECGDIAQPGTAERLVATAVATGLPVRGVLHAAAVVEDATLANITDELLARDWAPKVHGAWELHEATSGQPLDWFCLFSSAAALTGSPGQSAYSAANSWLDAFAHWRQAQGLPATAIAWGAWSDIGQLGWWSASPARASALEESNYTAITPDEGAYAFEALLRHNRVYTGYAPVIGAPWLVAFAERSRFFEVFSSSNGSGTSKFRVELNELPRDEWPARLRQLVAEQVSLILRRTVDPDRPLPEYGLDSLGALELRTRIETETGIRLAPKNVSATVRGLADHLYEQLAPDDAPAAALSSQ
What is the function of this protein?
Involved in sulfolipid-1 biosynthesis.  Catalyzes the synthesis of the hepta- and octamethyl phthioceranic and hydroxyphthioceranic acids, the methyl-branched acyl constituents of sulfolipids.
What are the official names of this protein?
Phthioceranic/hydroxyphthioceranic acid synthase, Polyketide synthase pks2.
Protein: CLPS_AROAE
Sequence: MATQKQDEFLLETEQTRTKPPPLYKVLLLNDDFTPMDFVIVVLQKFFGMDRERATRVMLQVHREGMGVCGVFPKDVAATKVEQVVAFARQHQHPLACVMEEN
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: NOS2_RAT
Sequence: MACPWKFLFRVKSYQGDLKEEKDINNNVEKTPGAIPSPTTQDDPKSHKHQNGFPQFLTGTAQNVPESLDKLHVTPSTRPQHVRIKNWGNGEIFHDTLHHKATSDISCKSKLCMGSIMNSKSLTRGPRDKPTPVEELLPQAIEFINQYYGSFKEAKIEEHLARLEAVTKEIETTGTYQLTLDELIFATKMAWRNAPRCIGRIQWSNLQVFDARSCSTASEMFQHICRHILYATNSGNIRSAITVFPQRSDGKHDFRIWNSQLIRYAGYQMPDGTIRGDPATLEFTQLCIDLGWKPRYGRFDVLPLVLQAHGQDPEVFEIPPDLVLEVTMEHPKYEWFQELGLKWYALPAVANMLLEVGGLEFPACPFNGWYMGTEIGVRDFCDTQRYNILEEVGRRMGLETHTLASLWKDRAVTEINAAVLHSFQKQNVTIMDHHTASESFMKHMQNEYRARGGCPADWIWLVPPVSGSITPVFHQEMLNYVLSPFYYYQIEPWKTHIWQDEKLRPRRREIRFTVLVKAVFFASVLMRKVMASRVRATVLFATETGKSEALARDLAALFSYAFNTKVVCMEQYKANTLEEEQLLLVVTSTFGNGDCPSNGQTLKKSLFMMKELGHTFRYAVFGLGSSMYPQFCAFAHDIDQKLSHLGASQLAPTGEGDELSGQEDAFRSWAVQTFRAACETFDVRSKHCIQIPKRYTSNATWEPEQYKLTQSPESLDLNKALSSIHAKNVFTMRLKSLQNLQSEKSSRTTLLVQLTFEGSRGPSYLPGEHLGIFPGNQTALVQGILERVVDCSSPDQTVCLEVLDESGSYWVKDKRLPPCSLRQALTYFLDITTPPTQLQLHKLARFATEETHRQRLEALCQPSEYNDWKFSNNPTFLEVLEEFPSLRVPAAFLLSQLPILKPRYYSISSSQDHTPSEVHLTVAVVTYRTRDGQGPLHHGVCSTWINNLKPEDPVPCFVRSVSGFQLPEDPSQPCILIGPGTGIAPFRSFWQQRLHDSQHRGLKGGRMTLVFGCRHPEEDHLYQEEMQEMVRKGVLFQVHTGYSRLPGKPKVYVQDILQKELADEVFSVLHGEQGHLYVCGDVRMARDVATTLKKLVAAKLNLSEEQVEDYFFQLKSQKRYHEDIFGAVFSYGAKKGNTLEEPKGTRL
What is the function of this protein?
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body.  In macrophages, NO mediates tumoricidal and bactericidal actions.  Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2.  As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S-nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM.  Involved in inflammation, enhances the synthesis of pro-inflammatory mediators such as IL6 and IL8.
What are the official names of this protein?
Nitric oxide synthase, inducible, Inducible NO synthase, Inducible NOS, iNOS, NOS type II, Peptidyl-cysteine S-nitrosylase NOS2.
What is the protein family that this protein belongs to?
Belongs to the NOS family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Note=Localizes as discrete foci scattered throughout the cytosol and in the presence of SPSB1 and SPSB4, exhibits a more diffuse cytosolic localization.
Protein: LYXK_ECOLI
Sequence: MTQYWLGLDCGGSWLKAGLYDREGREAGVQRLPLCALSPQPGWAERDMAELWQCCMAVIRALLTHSGVSGEQIVGIGISAQGKGLFLLDKNDKPLGNAILSSDRRAMEIVRRWQEDGIPEKLYPLTRQTLWTGHPVSLLRWLKEHEPERYAQIGCVMMTHDYLRWCLTGVKGCEESNISESNLYNMSLGEYDPCLTDWLGIAEINHALPPVVGSAEICGEITAQTAALTGLKAGTPVVGGLFDVVSTALCAGIEDEFTLNAVMGTWAVTSGITRGLRDGEAHPYVYGRYVNDGEFIVHEASPTSSGNLEWFTAQWGEISFDEINQAVASLPKAGGDLFFLPFLYGSNAGLEMTSGFYGMQAIHTRAHLLQAIYEGVVFSHMTHLNRMRERFTDVHTLRVTGGPAHSDVWMQMLADVSGLRIELPQVEETGCFGAALAARVGTGVYHNFSEAQRDLRHPVRTLLPDMTAHQLYQKKYQRYQHLIAALQGFHARIKEHTL
What is the function of this protein?
Catalyzes the phosphorylation of L-xylulose and 3-keto-L-gulonate.  Is involved in L-lyxose utilization via xylulose, and may also be involved in the utilization of 2,3-diketo-L-gulonate.
What are the official names of this protein?
L-xylulose/3-keto-L-gulonate kinase, L-xylulokinase, 3-dehydro-L-gulonate kinase.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: GUAA_SYNC1
Sequence: MSQDIHGEKILILDFGSQYTQLIARRVREAHVYCELHPFDMDLDAIRAFGPKGIILSGGPKSVYEEGAPVVEEALFELGIPVLGICYGMQLMSRHFGGRVVPAGKREYGHATLLPCGSPGPLFDEFFVDGKSPVWMSHGDHVEQVPDGFEVVGCSENAPVCAIQDIARDLYGVQFHPEVNHTPRGEQLLDTFVRQICGCTGQWTPGQIIEDAVVRIREQVGSERVILGLSGGVDSSVAAALIQRAIGDQLVCVFVDNGLLRLDEGDQVMRTFAQNMGVNVIRVNAQDRFMTALAGESDPERKRKIIGNLFVEIFEEESANIEDATWLAQGTIYPDVIESAGAKTGKAHNIKSHHNVGGLPEHMKLKLLEPLRELFKDEVRAIGEELGLPHPMVYRHPFPGPGLGVRILGEVKPEYADILRRADAIYIEELYRTGHYDKISQAFAVFLPVKSVGVMGDGRTYEYVIALRAVETKDFMTAGWYPLPYADMAHISGRIINEVKGVNRVVYDISSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: MACB_RHOBA
Sequence: MIQLYGLRKDYRVGDHDLPVLKGITLNIEAGEYVALMGSSGSGKTTLMNLLGSLDHPTDGDYHLAGIDVSSLTPLELAAFRSQHIGFVFQNFNLLPRATALDNVMLPTIYASDGRSRRECIEDATKLLESVGLGGRLDHMPNQLSGGERQRIAIARALMNRPKLLLADEPTGNLDTVTEQEILALFRQLNQEHGITLVVVTHDAEVAHEADRVVRMKDGLVAEDVRQRASTVDRSRLANSRAEPLREPASAWSLPATWNAIVVAVLALRRNALRTVLTMLGVIIGVASVISTMELSAGASTAIEETVASMGASMLTISPGKASSTSGRQRPIQIIPDDVVAVAEQCSAVKVAAPLVYSQVQLVRQNRRWSPNLALGTTSQYLAARNWDQLELGTPFTQEQVLDAAKVCILGKTVAHELFDSEYPIGEEIRVNGVPLRVVGVLTEKGGDVIGNDQDDIIIGPWTTFKLRVNSSTGATAQFSTFADQMPPMQLASTRRSTQREEIHQIYVEAESPDHVELARQQITQVLSRRHNVEPAGAYRINDITEVSKVVGQVVGGVSALGLVIAGVSLMVGGVGIMNIMLVSVTERTREIGLRMAVGANRSAILRQFLIEATVLCVVGGFIGIFAGHMWSVLVGRVIGWPTAMSIWAPIVAVTVAATVGIVFGYYPARTASRLNPIDALRYE
What is the function of this protein?
Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation.  Confers resistance against macrolides.
What are the official names of this protein?
Macrolide export ATP-binding/permease protein MacB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SLYX_SHEPC
Sequence: MQGVQEQIEELQTKLAFQELTVEELNQEVIKLNRLVAYQQHQIQLLVGKLQAMEPSNIATQAEETPPPHY
What are the official names of this protein?
Protein SlyX homolog.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.
Protein: SPLD_STAAE
Sequence: MNKNIIIKSIAALTILTSITGVGTTVVDGIQQTAKAENSVKLITNTNVAPYSGVTWMGAGTGFVVGNHTIITNKHVTYHMKVGDEIKAHPNGFYNNGGGLYKVTKIVDYPGKEDIAVVQVEEKSTQPKGRKFKDFTSKFNIASEAKENEPISVIGYPNPNGNKLQMYESTGKVLSVNGNIVTSDAVVQPGSSGSPILNSKREAIGVMYASDKPTGESTRSFAVYFSPEIKKFIADNLDK
What are the official names of this protein?
Serine protease SplD.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1B family.
What are the subcellular locations of this protein?
Secreted.