PharMolix/UniProtQA huggingface dataset:
Protein: SSRP_CHLAD
Sequence: MATKTNHIAVVAENRKARHDYDIEETIEAGIVLSGSEIKSVRAGRVNLRGSFARVIDDEVFLYDAHIAPYEQSGKYFNHDPLRPRKLLLHRREINRLNGLVRMKGMTLVPLKIYLKGRRAKVELGIARGKKIYDKREDIARRDAERDIERALKRRIRE
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: HETN_HAEDE
Sequence: XTLSEPEPTCSIEYFRYQAIEDCEYSISVK
What is the function of this protein?
Cleaves fibrinogen Aalpha (FGA), gamma (FGG) and Bbeta (FGB) chains.  Degrades cross-linked fibrin.  Has no amidolytic, plasminogenolytic or caseinolytic activity.  Inhibits platelet aggregation induced by collagen (IC(50)=7. 5ug/ml) and various other agonists, presumably via activation of a nitridergic pathway.  Inhibition is accompanied by reduced ATP release from and surface expression of SELP and CD63 on platelets as well as increased intracellular levels of Ca(2+), cGMP and nitric oxide synthase activity.
What are the official names of this protein?
Hementerin.
What are the subcellular locations of this protein?
Secreted.
Protein: IF2P_METS5
Sequence: MSKTEVRLRQPIVVVLGHVDHGKTTLLDKIRGTAVVKKEPGEMTQEVGASFVPSSVIEKVAQPLKGIIPVKLEIPGLLFIDTPGHELFSNLRRRGGSVADIAILVVDITEGFQKQTIESIEILKDKKVPFLVAANKIDRIPGWRPIENETFTKSFRSQSQSVQKALDNYVYKLVMQLAEMGFNAERFDRVRDFTRYVSIVPVSGKTGEGLPELLALLAGLTQQYLKTRLRAVEGPAKGVILEVKEEQGLGHTIDVIIYDGILRKSDTIVLGGINGVIVTKIRNILLPAPLQDMRMTRSGYRSIDEISAAAGVKISAPGLEEALAGSPLYVANDEAKLQEARKLIEEELSKVRFSKNSTGIVVKADSLGSLESLVAGFEKIGIPVRVADIGPITKRDLIEAELSAKEVEEYGIIAAFRVKPIPGLDTSKVKIIYNDIIYQLIDDTIKYIEDLRERRKRRTLDSLVLPGKIKILPGYVFRRSDPAIVGVEVLGGVVRPKYPLIREDGQRVGEVLAIQDNKKNIERATKGMEVSMSIKGNIMIGRQVQEGDVLYTDVPQEDLEILFKNYKDSITEDMMEVIKELIKIKKAENPLYGIFIQ
What is the function of this protein?
Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes.  Seems to function along with eIF-2.
What are the official names of this protein?
Probable translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
Protein: TDPC2_ARATH
Sequence: MIPTTATVDDEPGQIKRALIDASAGAISGGVSRSVTSPLDVIKIRFQVQLEPTTSWGLVRGNLSGASKYTGMVQATKDIFREEGFRGFWRGNVPALLMVMPYTSIQFTVLHKLKSFASGSTKTEDHIHLSPYLSFVSGALAGCAATLGSYPFDLLRTILASQGEPKVYPTMRSAFVDIIQSRGIRGLYNGLTPTLVEIVPYAGLQFGTYDMFKRWMMDWNRYKLSSKIPINVDTNLSSFQLFICGLGAGTSAKLVCHPLDVVKKRFQIEGLQRHPRYGARVERRAYRNMLDGLRQIMISEGWHGLYKGIVPSTVKAAPAGAVTFVAYEFTSDWLESISW
What is the function of this protein?
Mitochondrial transporter that mediates uptake of thiamine diphosphate (ThDP) into mitochondria.
What are the official names of this protein?
Mitochondrial thiamine diphosphate carrier 2.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TIG_SPHAL
Sequence: MKTVETLNEGLKREYRVTITAKDIDARVDEEVKSIAPTVRMPGFRPGKVPPNLIRKMHGAALSADALNKAIDAGVRDLMAKEKLRPALQPAVTLADGYEAGKDAELTVALEVLPEIETPSIDGLKLERLTVPADDKAVMAKIEEFAAQMKRFEEAPKTRKAATGDQVIIDFAGSVDGTPFDGGTGEDMAVEIGSGQLIPGFEDQLVGVKAGDEKTLKVTFPEDYPVETLKGKLAEFAVTVKEVKVPAATKIDDEFAKSLGLESLDKLKELMKDQVEQELNGLTRTHMKRKLLDQLAAAHDFEVPPTMVEAEFNQIWQQLEHEASHEEDPEAAKAELENDREEYRAIAVRRVRLGLLLSEIGQAHGVQVSQQEMQRLIMQAAQQYRPEDRQRFVEYVQQDALAAAQLRAPLYEDKVVDFLFEKAEITDRETTREELEAAIEADDDSGHVHGPGCGHDHDEKPAKKAAAKKPATKKEAVKDEAKAEEAPAKKAPAKKAEPKAEAKPAAAKKAAPAKAAAEEKAEPAKKAPAKKAAAKK
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: MDH_AERHH
Sequence: MKVAVLGAAGGIGQALALLLKNRLPAGSELSLYDIAPVTPGVAVDLSHIPTDVKVKGFCGEDPSPALVGADVVLISAGVARKPGMDRSDLFNINAGIVKNLVEKCAASCPKALIGIITNPVNTTVAIAAEVLKKAGVYDKRRLFGVTTLDVIRAETFVAEAKGLNVDKVRVNVIGGHSGVTILPLLSQIEGASFTADEVAAMTKRIQNAGTEVVEAKAGGGSATLSMGQAACRFGLSLIKGLQGEANVIECAYVEGDGKHATFFAQPILLGKNGVETVLDYGKLSAFEQEAMDGMLATLKADIQLGVEFVK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: GCDH_PIG
Sequence: KGGKTQGRSAKSSRPEFDWRDPLVLEEQLTADEILIRDTFRTYCQEHLMPRIVLANRNEVFHREIISEMGELGVLGPTIKGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQQQQKYLPRLAKGELLGCFGLTEPNHGSDPGSMETRALHNPSNRSYTLNGAKTWITNSPVADLFVVWARCEDNCIRGFLLEKGMRGLSAPKIEGKFSLRASATGMIIMDDVEVPEENVLPKASSLAVPFGCLNNARYGISWGVLGAAEFCLHTARQYTLDRIQFGVPLAKNQLIQRKLADMLTEITLGLHACLQLGRLKDQDKVTPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGRAITGIQAFTTDK
What is the function of this protein?
Catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism.  It uses electron transfer flavoprotein as its electron acceptor.
What are the official names of this protein?
Glutaryl-CoA dehydrogenase, mitochondrial, GCD.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RL14_MYCAP
Sequence: MVLELSKLNVADNSGAKEVGVIRVLGGSRKKTANIGDVIICSVKKAIPTGIVKEGQVVKAVIVRSVYGIHRENGQHIRFDDNAVVIIKDDKTPRGTRVFGPVARELRDKGYLKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: PPR36_HUMAN
Sequence: MYRVPEFYARRKRLGGQTPYLMDQLGLRLGMWYWKDETRTLEFRRFAAEDSVQWLLKHHPHFTPAAEVKEKGKKGKAVHFAETDGPASDRLTDKRLAAKDDKSAKAVEKRGQQGTITLDDVKFVTLLLLQDTEMQRICSFTTFMRNKNLDNFLMALLYYLSHYLEKNSLEKKPKSYMVGLVEKKEMELVLSELEAAQRYLAQKYCILVLGLAVPDKHHMCCGKEKISDTQKDWKFFESFYTFCTYVAWIVFRRQHLTEIEEEVGRLFRTNMFNIPRRRREDEESGGEKKRMTFVQFRRMMAKRPAIKKAINMRSPVMSTLLPSLREKAQNVFEKKYHQVDVRFPAEMQKHVGTLDSVPMPVVGILGEPRCLFNPHTLHPLDPEENTKSFGRYPSLMENNNMRIQDTLDLVMKTLSSHTSCPK
What is the function of this protein?
Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes.
What are the official names of this protein?
Protein phosphatase 1 regulatory subunit 36.
Protein: DNLJ_PHOV8
Sequence: MTEIERIDQLREELHRHNYNYYVLNAPEITDQEFDKLMRELQDLEEKHPEHRDENSPSMRVGSDINKNFTQVVHKYPMLSLANTYSETEVTEFYDRVKKSLNEDFEICCEMKYDGTSISLTYENGKLVRAVTRGDGVQGDDVTGNVKTIRSIPLVLHGKGYPETFEIRGEILMPWVVFEELNKEREAREEPLFANPRNAASGTLKLQNSAIVASRKLDAYLYYLLGDNLPCDGHYENLKEAEKWGFKISDLTRKCKTLQEVFDFIKYWDVERKNLPVATDGIVLKVNSLRQQRNLGFTAKSPRWAIAYKFQAEQALTRLNKVTYQVGRTGAVTPVANLDPIQLSGTVVKRASLHNADIIEGLDLHIGDMVYVEKGGEIIPKIVGVDKDARIMIGDKVKFITHCPECGSKLVRYEGEAAYYCTNDAACPPQIKGKIEHFISRRAMNIDGLGPETVDQFYQEGLIRDVADLYTLKTSDIINLERMGEKSAENIIKGIEQSKEVPFERVLFALGIRFVGETVAKKVAKSFKSMDALADASLDNLIHVDEIGEKIAQSILLYFANPKNRDIIERLRVAGVRLEADEEDTSEHTDKLAGKSIVISGVFAHHSRDEYKELIEKHGGKNVGSISSKTSFILAGDNMGPSKLEKAQKLGVTIVSEEEFLQMIE
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: ADDA_STRSV
Sequence: MKRIPFLTAEEIALKQAQEAASDKPQKKTAEQIEAIYSSGRNILVSASAGSGKTFVMVQRIIDQILRGVAVSQLFISTFTVKAAGELKERLEKELGQALKEAESPELKQHLAQQLADLPNADIGTMDSFTQKVLSRYGYLLGLAPNFRILQSASEQLILQNEVFSQVFDHYYDSERQALFSRLVKNFTGKRKDLSAFREQVYRIYSFLQSTSSPQRWLEETFLYGYEHSDFAAERERIFCQIKSALWELETFFSAHLEHEGREFAGAKYQENVQDALTVLAGLNESSSIEETAQILKQIVALSQLSNGQAFTARVGKNADELKKEMAKDYNEARKPMIERLRSFDQQLYQLDFIEQHQDECLPLVELLRDFVADFAQAYLERKKAENAFEFGDISHFAIEILETFPEVRRFYQERYHEVMVDEYQDTNHTQERMLDLLSRGKNRFMVGDIKQSIYRFRQADPQIFSDKFKAYQEDSSQGKLIVLKENFRSHLEVLEATNDVFKRLMDEEVGEIDYNETHYLVAGNPAKREPNPANRASFLIYEGSKESPEEEADEGLPQAVSAGEVDLVIKEIIRLHNEEGVAFKDITLLTASRTRNDLILAAFEQHQIPLVPDDGAANYLQSVEVLVMLDTLRTINNPLNDYALTALLKSPMFDFGEDELARLSLQASQERSQENLYEKLVNALEGRGLNPALVTEELQKKLQHFYETLQSWRTYSKTHSLYDLIWKIYQDRFYYDMVGTLVNGAQRQANLYALSLRANEYEKSSFKGLSRFIGMIDRILENQHDLASVPVAAPKDAVRLMTIHKSKGLEFKYVFLLNMDKAFNRQDSSSAIILSRTKGVGIKYVADVSVSVKDSYAPNQLRISMDTLPYQQNLAELQLASLSEQMRLLYVAMTRAETKLYLVGKGSQEALDKRQWGKSQQGRLSASLRSQISNFQDWLYAIQDVFSDENLAYETRFVTDEELTAEEIGRINEPVLFPADDLADNRQSDDIRRALDILESVDRLNSQYRSAIELPSVRTPSQIKKFYEPIMDTDGLDIMDERAAFRPQPSFELPDFGKKAKVTGAQVGSAVHELMQRIPLDSSPSMAVLRSALAQVQADDAVKKQIQLSKIASFFETDLGRLLIENSDRVRREAPFAMLKRDEASGQEFVLRGILDGYLLFEDRIILFDYKTDKYKDSSELIARYRGQLDLYAQALSRSYGISQIEKYLILLGGEQLQVVKVD
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.
What are the official names of this protein?
ATP-dependent helicase/nuclease subunit A, ATP-dependent helicase/nuclease AddA, DNA 3'-5' helicase AddA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddA subfamily.
Protein: URE1_CALS8
Sequence: MAYHIKREDYVKIYGPTVGDKIRLADTDLIIEIEKDYTVYGEECKFGAGKNIRDGMSQNQFACNNSALDIVITNVVIIDWWGIVKGDIGIKDGKIVGIGKAGNPNVMDGVTPNMVIGPSTDVISGEGLIATAGAIDTHVHFICPQQIETALYKGITTLIGGGIGPTEGTKATTCTPGAWNIFKMLKAVDNFPVNIGLTGKGNSSYEKPLIEQVKAGVVGFKIHEDWGATPTVIDTCLKVADEFDVQVALHTDSMNEAGFVEDTIKAIGNRVLHAYHVEGAGGGHAPDVLKVVQYKNIIPSSTTPTMPHTINTFSEHLDMLIFCHHLDKNLEEDVEFAKARIRETTMAAEDYLHDIGAISIINSDSQAMGRIGEVITRTWQTADKMKKIYGRLPEDTQNDNYRVKRYISKYTINPAIAHGISQYIGSLEPGKIADIVLWKPAFFGVKPEMIIKGGFIIASKMGDANASIPTPQPVIMKKMFGAFGKAVYDTAVTFVSGYFYENEINKKIGINKKVLPVKNCRNISKENMIYNNQLPKIEIDYKTFEVFVNGNKINVPPAVSLNMTRRYNLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_DEHMC
Sequence: MANQIDESKPISDLEIMRHSAAHIMAEAVLSMFPEAKLGIGPAIDTGFYYDFDLPRTLTPEDLPEIETRMNQLVKSNLPFRREEMSKDEARKLFANQPYKLELLNDITDETVSIYRQGNFCDLCRGPHVNYTSKVKAFKLLSIAGAYWRGDEKRPMLQRIYGAAFLDKASLAEYLNMLEEAAKRDHRKLGKELELFSLHQEIGGGLVNWLPNGAIVRHLIEEFWKKEHLKRGYDLVYTPHIAKVDLWKTSGHWGFYRENMYSPMDIDGEEYVLKPMNCVYHILMFKNRTRSYKELPIRMAELGTVYRYERSGVLHGLSRVRGFTQDDAHIFCLYDQLEKEVVKVLDLAKFMIDTFGFTKYKVMLSTRPEKYVGELDKWEYATDILAKALEANQIPYQVDPGEGVFYGPKIDIKFEDALGRTWQGPTIQVDFQLPERFDVSVVGEDGKDQPVAMVHRTVLGSMERFMSCLTEQYGGAFPAWLSPKQVMVIPIADRHTEFAEKLACELREEEVRVEVDSRSETMNQKIRQAQLAKIPYMLVVGDKEIETQSVAVRTRTGSQQVMPFAEFKSMLLAKIKTKSTEI
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFSA_CLOBM
Sequence: MKITKNILKAEFIKRPNRFQAYVKINEKIEMVHVPNTGRCKEILIPGSTVILREENNENRKTRYDLIAGYKGDMLISIDSQIPNKVVYEALMNFKIEILKEYANIKREKTFGKSRFDFKLEKENGEVYYLEVKGVTLENDGLTMFPDAPTERGTKHILELIDVKNKGMGAGVLFLIQLNGVKKFTPNHKMDKNFGEALRLAKEKGVDILAYDCLVEESSISLNNPVSIEI
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: PUR7_BIFLO
Sequence: MEKLEKLYEGKAKQLYATDDPEVLWVEYKNTATAGDGEKKEDFTGKGRLNNLITTIIFDLLKKRGIDSHLIKRVDDTGQLVRKVNMFPLEIVLRNVAAGHFCSRLGVEEGLPLKEPVLEYFLKNDDLHDPFVNDDDLVALGVCTREDLAEIAPLARKINEALIEIFAKIDVKLVDFKIEMGRATDGTLLLADEITPDSCRLWDQKDHSGKVEHLDKDLFRRGLGSIIPAYEEIEERLAELAKSEGIEVAE
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: GLMM_THEP3
Sequence: MARLFGTDGVRGIANYDLTPQLAFELGRAGAYVLTHGTHRPKVVVGKDSRISGDMLECALTAGLTSVGAEVISVGIIPTPAVAYLTRLYQADAGVMISASHNPVEYNGIKFFDKDGYKLPDEVEDRIENIIKEKIELPSPIGTGIGTRKEYTNSHRDYIEFLKSTIDGDLKEMKIVIDCAYGASSTIAPILFKELGAEVILHGAEPIGEKINVNCGSTHPEKLQQLVIENGADIGLAFDGDADRLIAVDEKGNVVDGDHIMAICAIDLKKKGRLKNNTVVATVMSNIGFEIALKEQGINLIRTKVGDRYVLEEMTKGGYSIGGEQSGHIIFLDDNTTGDGEITALKLCSISKESGKKLSELAACMITYPQVLINAKVKNELKNAYLEDEEIKREIENLEREMRGEGRVLIRPSGTEPLVRVMVEGKDYDKISQMAKELAELIERKLN
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: RFAH_ECOLI
Sequence: MQSWYLLYCKRGQLQRAQEHLERQAVNCLAPMITLEKIVRGKRTAVSEPLFPNYLFVEFDPEVIHTTTINATRGVSHFVRFGASPAIVPSAVIHQLSVYKPKDIVDPATPYPGDKVIITEGAFEGFQAIFTEPDGEARSMLLLNLINKEIKHSVKNTEFRKL
What is the function of this protein?
Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components.  RfaH is recruited into a multi-component RNA polymerase complex by the ops element, which is a short conserved DNA sequence located downstream of the main promoter of these operons.  Once bound, RfaH suppresses pausing and inhibits Rho-dependent and intrinsic termination at a subset of sites.  Termination signals are bypassed, which allows complete synthesis of long RNA chains.  Enhances expression of several operons involved in synthesis of lipopolysaccharides, exopolysaccharides, hemolysin, and sex factor.  Also negatively controls expression and surface presentation of AG43 and possibly another AG43-independent factor that mediates cell-cell interactions and biofilm formation.
What are the official names of this protein?
Transcription antitermination protein RfaH.
What is the protein family that this protein belongs to?
Belongs to the RfaH family.
Protein: ZBT18_RAT
Sequence: MEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHLFYKDQLDKRDIVHLNSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVKVCKKKLKEKATTEADSTKKEEDASSCSDKVESLSDGSSHMAGDLPSDEDEGEDDKLNILPSKRDLAAEPGNMWMRLPSDAAGIPQAGGEAEPHATAAGKTVASPCSSTESLSQRSVTSVRDSADVDCVLDLSVKSSLSGVENLNSSYFSSQDVLRGNLVQVKVEKEASCDESDVGTNDYDMEHSTVKESVSANNRVQYEPAHLAPLREDSVLRELDREDKASDDEMMTPESERVQVEGGMESSLLPYVSNILSPAGQIFMCPLCNKVFPSPHILQIHLSTHFREQDGIRSKPAADVNVPTCSLCGKTFSCMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGDLYRHIRKFHCELVNSLSVKSEALSLPTVRDWTLEDSSQELWR
What is the function of this protein?
Transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain development.  Specifically binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes.  Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2 inhibitors of skeletal myogenesis.  Also involved in controlling cell division of progenitor cells and regulating the survival of postmitotic cortical neurons.  May also play a role in the organization of chromosomes in the nucleus (By similarity).
What are the official names of this protein?
Zinc finger and BTB domain-containing protein 18, 58 kDa repressor protein, rRP58, Transcriptional repressor RP58, Zinc finger protein 238.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family. ZBTB18 subfamily.
What are the subcellular locations of this protein?
Nucleus. Note=Associates with condensed chromatin.
Protein: XERDL_STRMU
Sequence: MITFISKFLASKSLTLNSQKSYLYDLQQFAEIIGEEVTPNKLKLYEQSLADLKVSAKKRKISAVNQFLFFLYENEVLDRFYKIKNKEKLPLLTPAYQEVDLSVLYRKIGDSKGQLIALLIVELGLSPSEIIQLKWENIALEFQVLTIVNEKVMRILEIPQLLLPYLEGEHKAVYLFDNKGEAYSRQWLFQKLNYYLASVDLSQMTAQKLREQYIIKEKNKGTAILDLTRKLGLKSPVTLEKYFKN
What is the function of this protein?
Putative tyrosine recombinase.  Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site.
What are the official names of this protein?
Tyrosine recombinase XerD-like.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerD-like subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLCA_YERP3
Sequence: MTHSTQQLSPEGVAEGKRGRLIRELVNRDKTPLIILIMAAVVGVVTGLLGVAFDRGVDWVQQQRLLALANVADYALLVWPLAFIMSALLAMMGYFLVSRFAPEAGGSGIPEIEGAMEEMRPVRWWRVIPVKFIGGLGTLGAGMVLGREGPMVQMGGNSGRMIVDIFRLRSPEARHSLLATGAAAGLSAAFNAPLAGILFVIEEMRSQFRYSLVSIKAVFIGVITSTIVYRYFNGERAIIEVGKLSDAPLNTLWLYLLLGIIFGAVGVIFNALIFRTQDMFVRFHGGDWRKLVLIGGLLGGMCGLLALLHGNAVGGGFALIPIAAAGNFSIGMLLFIFIARVITTLLCFGSGAPGGIFAPMLALGTILGTAFGLSCAHFFPQYGIEAGTFAIAGMGALFAASVRAPLTGIVLVLEMTDNYQLILPMIVTCLGATLIAQFMGGKPLYSAILARTLAKQEQARATVIAQEPAVENTPQTGR
What is the function of this protein?
Proton-coupled chloride transporter.  Functions as antiport system and exchanges two chloride ions for 1 proton.  Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.
What are the official names of this protein?
H(+)/Cl(-) exchange transporter ClcA.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClcA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GUF1_BRUMA
Sequence: MAVTRAAAPMVGNCSSAMLIIGRRYFSSPFTEKLRKTNRKKVIDLAAYPPKKIRNFGIVAHVDHGKSTLADRFLEMTGAVEKSSHASQMLDKLQVERERGITVKAQSCTMFHKDCMLNLIDTPGHADFSFEVARSLTATNGILLLVAANQGVQAQTVANFWLAFEAGLTIIPVINKVDLKSANVPRVVSQMENLFDFLPSEILYISAKNGTGIGDVLDAVVERLPPPKVEAHSPLRAHVFDSWYETHHGPVVCVAVHDGVISKGQRIRTYHSDCEYEVLVVGIMIPNMYEVKCLYAGQVGYLLTTMKSVQDAVIGETLYDVSDERNMVQPMPLITPTPPCIYASIYPTNINEYNALRVALYKLALNDSSVQIQHSNSTALGNGFKIGFSGHLHMEEYDANITITAPSVEYRAVIKDNQTILKKRYNGQRVIRLLDASDFPVCPSDIDHFLEPMIKLTLLLSTAYCEHVERLCVDARGEQVENNGLDTDCIMQQWRLPFAEVCMDFFDRLKRITSGYVTYNYQWDGFQKATIELLMIHINDLPIYEFSEIMPSNQIKARAKEIVKKLKEEIPRQQYEVRIKATLGQSKKALVQTVIAPVKKDFTGRLKGNFGGSGWERFCKKLSHQKKGKERMKQLGQVQIPKEAFINVLRR
What is the function of this protein?
Promotes mitochondrial protein synthesis.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Binds to mitochondrial ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Translation factor GUF1 homolog, mitochondrial, Elongation factor 4 homolog, EF-4, GTPase GUF1 homolog, Ribosomal back-translocase.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: SCP30_ARATH
Sequence: MDNHTKSFSSLLISLWFTALLILVEMVSCARQHRRSFLAKEADLVTNLPGQPDVSFKHYAGYVPVDKSNGRALFYWFFEAMDLPKEKPLVLWLNGGPGCSSVGYGATQEIGPFLADTNEKGLIFNPYAWNKEVNMLFLESPVGVGFSYSNTSSDYLNLDDHFAKKDAYTFLCNWFEKFPEHKGNEFYIAGESYAGIYVPELAELVYDNNEKNNDLSLHINLKGFLLGNPDISNPDDWRGWVDYAWSHAVISDETHRNINRLCNFSSDDVWNNDKCNEAIAEVDKQYNEIDIYSLYTSACKGDSAKSSYFASAQFKTNYHISSKRMPPRRLAGYDPCLDDYVKVYYNRADVQKALHASDGVNLKNWSICNMEIFHNWTYVVQSVLPIYQKLIAGGLRIWVYSGDTDGCIPVLGTRYSLNALGLPIKTAWRPWYHEKQVSGWVQEYDGLTFATFRGAGHTVPSFKPSSSLAFISAFVKGVPLSSSRVETN
What is the function of this protein?
Probable carboxypeptidase.
What are the official names of this protein?
Putative serine carboxypeptidase-like 30.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Secreted.
Protein: GSHR_NEUCR
Sequence: MAPISRETDFLVIGGGSGGIATARAAAGKYGIKSMVVEGKRLGGTCVNVGCVPKKVTFYAALVAETIHQAKDYGFSVEQTAPFDWPTFKQKRDAYVARLNGIYERNLANDKVEYVHGWAKLLSPNSVEVTLDDGTKSVVNAKKILIAVGGNPTIPPHIPGSEYGTNSDGFFDIDTLPKKVALVGAGYIAVEFAGMLNALGVETHLFIRHDTFLRSFDPMIQQVSVKEYERIGVKVHKKSQLTSVQKDAAGKLAINFKEGEGEQSISDVDHLIWAVGRTPAVEGLGLDKAGVKTNEKGYIEVDEYQNTSTENIYAVGDVCGQVELTPVAIAAGRKLAARLFGPEEFRTLKLNYDNVPSVVFAHPEIGSIGLTEPEAVAKYGAENLKIYKSSFTAMYYAMMKPEDKAPTAYKLICAGPEEKVVGLHIIGLGSGEILQGFGVAVNMGATKADFDNCVAIHPTSAEELVTLK
What is the function of this protein?
Maintains high levels of reduced glutathione in the cytosol.
What are the official names of this protein?
Glutathione reductase, GR, GRase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNFD_SHEB2
Sequence: MAFKIASSPHVTRNLHTSTVMQRVILCLLPGLVVQCAFFGWGTLVQVLLAILVALSCEAAVMKLRNRNIKASLSDNSAMLTAILIGVAIPPLAPWWMIVMGTAFAIVIVKHLYGGLGHNLFNPAMAAYVLLLVSFPVQMTTWIAPSTVALHSPSLVESLQLIFNVGAHVNMEQFRLGIDGMTMATPLDTLKTDLSMGLTTTESLTKAIFDGSTGVGWFWVNLAYLAGGLVLLKLKAIRWHISTGVLLGLFVASSIGFLLSPDTQASPLMHLFSGATMLAAFFIATDPVTAATSSRGRIIFGALIGVLVYIIRTKGGYPDAFAFAVLLANLCAPFIDYYVRPRTYGHSTS
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit D, Rnf electron transport complex subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS8_MARMS
Sequence: MSRFWTDKIASLDPYVPGEQPQDKKYIKLNTNESPYSPSPKAIEAMALEVSERLRLYPDPNCATLKNALAKSYQLDANQVFVGNGSDEVLALAFMGYFAGGKPLAFADITYSFYKVYAGLYSIEPKLIPLNDDFDIIPADYENLDVSGVVITNPNAPTGKALPLADIEAILKANPDVVVLVDEAYVDFGAQSAVSLINQYPNLLVVQTLSKSRALAGIRVGYALGHADLIEGLERLKNSFNSYPIDRVALVGATAAVEDEAYLKEICDKTIATREQSVKDLEALGFSIIPSATNFVFATHPEKNAEQIYLTLKERGILVRFFGSNKPRIGNYLRITIGTDEEMAALTAALKTL
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.