PharMolix/UniProtQA huggingface dataset:
Protein: FPG_STRA5
Sequence: MPELPEVETVRKGLERLVVNQEIASITIKVPKMVKTDLNDFMISLPGKTIQQVLRRGKYLLFDFGEMVMVSHLRMEGKYLLFPNKVPDNKHFHLYFKLTNGSTLVYQDVRKFGTFELVRKSSLKDYFTQKKLGPEPTADTFQFEPFSKGLANSKKPIKPLLLDQRLVAGLGNIYVDEVLWAAKIHPQRLANQLTESETSLLHKEIIRILTLGIEKGGSTIRTYKNALGEDGTMQKYLQVYGKTGQPCPRCGCLIKKIKVGGRGTHYCPRCQCL
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: XERS_STRP1
Sequence: MRRELLLEKIETYKAIMPWYVLDYYQSKLAVPYSFTTLYEYLKEYKRFFDWLMDADLTQAPKIADIDLSTLEHLTKKDLEAFVLYLRERPSLNTYSTKEGLSQTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLASRAENIKQKLFLGDETLAFLDYVDKEYEQKLSNRAKSSFRKNKERDLAIIALLLASGVRLSEAVNLDLKDVNLNMMIIEVIRKGGKRDSVNVAGFAKGYLESYLAVRQRRYKAEKQDLAFFLTEYRGVPNRMDASSIEKMVGKYSEDFKIRVTPHKLRHTLATRLYDATKSQVLVSHQLGHSSTQVTDLYTHIVNDEQKNALDNL
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.
What are the official names of this protein?
Tyrosine recombinase XerS.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_PROM2
Sequence: MTNSKKSSNNSLKNHELYAIAETSGQQFWFEVNRYYDIDRLKAKEKDKITLDKVLLLKDKDSITVGKPYVKDAKIELEVVSHKRDKKILVYKMRPKKKTRRKMGHRQELTRVMVKSIKVGKPTPKSSSKKEETVKKETKPKSEKSTN
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: E2FD_ARATH
Sequence: MDSLALAPQVYSRKDKSLGVLVANFLTLYNRPDVDLFGLDDAAAKLGVERRRIYDVVNILESIGLVARSGKNQYSWKGFGAVPRALSELKEEGMKEKFAIVPFVAKSEMVVYEKEGEESFMLSPDDQEFSPSPRPDNRKERTLWLLAQNFVKLFLCSDDDLVTFDSATKALLNESQDMNMRKKVRRLYDIANVFSSMKLIEKTHVPETKKPAYRWLGSKTIFENRFIDGSASLCDRNVPKKRAFGTELTNVNAKRNKSGCSKEDSKRNGNQNTSIVIKQEQCDDVKPDVKNFASGSSTPAGTSESNDMGNNIRPRGRLGVIEALSTLYQPSYCNPELLGLFAHYNETFRSYQEEFGREK
What is the function of this protein?
Inhibitor of E2F-dependent regulation of gene expression.  Binds specifically the E2 recognition site as a monomer without interacting with DP proteins.  May be up-regulating E2FA and down-regulating repressors of cell cycle progression.  Promotes cell proliferation and represses cell elongation.  Regulated by proteolysis via a ubiquitin-proteasome pathway.
What are the official names of this protein?
E2F transcription factor-like E2FD, DP-E2F-like protein 2, E2F-like repressor E2L1.
What is the protein family that this protein belongs to?
Belongs to the E2F/DP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYE_PSEMY
Sequence: MTTVRTRIAPSPTGDPHVGTAYIALFNLCFARQHGGQFILRIEDTDQLRSTRESEQQIFDALRWLGIEWDEGPDVGGPHGPYRQSERGEIYKQYSDELVAKGHAFPCFCSAERLDEVRAQQMANKETPRYDGHCMHLDPAEAQRRIAAGESHVVRMKVPSEGVCVVPDMLRGDVEIPWDRMDMQVLMKADGLPTYFLANVVDDHLMGITHVLRGEEWLPSAPKLIKLYEYFGWEQPALCYMPLLRNPDKSKLSKRKNPTSITFYERMGYLPQAMLNYLGRMGWSMPDEREKFSLNEMIEHFDINRVSLGGPIFDLEKLSWLNGQWLRELPVETFAAEVQKWALNPEYLMKIAPHVQGRVETFSQIAPLAGFFFSGALNLDAKLFEHKKLSPDQVRQLMQLILWKLESLRQWEKERITGCIQAVVEHLELKLRDAMPLMFAAITGQASSVSVLDAMEILGPDLTRFRLRQALELLGGTSKKETKEWEKLLASIA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PETD_SYNP2
Sequence: MSIMKKPDLSDPKLRAKLAQNMGHNYYGEPAWPNDILFTFPICIAGTIGLITGLAILDPAMIGEPGNPFATPLEILPEWYLYPVFQILRVLPNKLLGIACQGAIPLGLMMVPFIESVNKFQNPFRRPVAMAVFLFGTAVTLWLGAGACFPIDESLTLGLF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 4, 17 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetD subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: CODY_STAA1
Sequence: MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLMEVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHSEVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGTFIKVKKEKFLDELEKSK
What is the function of this protein?
DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability.  During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.
What are the official names of this protein?
Global transcriptional regulator CodY.
What is the protein family that this protein belongs to?
Belongs to the CodY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10E_PICTO
Sequence: MVTKPARMYTRITGPAYTRKEFMGGVPYPKITTFIQGNQKKDFEIEMMLVAEEACQIRHTALEAARVSVNRKLLDAAGSDNYFLQIRPYPHQVIREHKMATGAGADRISSGMRAAFGRPVGTAARVYPGQIIMVGRVDRNNAKLLKDALHKASIKLPTPCKVVVTKGSKITESLGI
What are the official names of this protein?
50S ribosomal protein L10e.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: LRWD1_HUMAN
Sequence: MGPLSARLLMQRGRPKSDRLGKIRSLDLSGLELLSEHLDPKLLCRLTQLQELDLSNNHLETLPDNLGLSHLRVLRCANNQLGDVTALCQFPKLEELSLEGNPFLTVNDNLKVSFLLPTLRKVNGKDASSTYSQVENLNRELTSRVTAHWEKFMATLGPEEEAEKAQADFVKSAVRDVRYGPESLSEFTQWRVRMISEELVAASRTQVQKANSPEKPPEAGAAHKPRARLAALKRPDDVPLSLSPSKRACASPSAQVEGSPVAGSDGSQPAVKLEPLHFLQCHSKNNSPQDLETQLWACAFEPAWEEGATSQTVATCGGEAVCVIDCQTGIVLHKYKAPGEEFFSVAWTALMVVTQAGHKKRWSVLAAAGLRGLVRLLHVRAGFCCGVIRAHKKAIATLCFSPAHETHLFTASYDKRIILWDIGVPNQDYEFQASQLLTLDTTSIPLRLCPVASCPDARLLAGCEGGCCCWDVRLDQPQKRRVCEVEFVFSEGSEASGRRVDGLAFVNEDIVASKGSGLGTICLWSWRQTWGGRGSQSTVAVVVLARLQWSSTELAYFSLSACPDKGIVLCGDEEGNVWLYDVSNILKQPPLLPAALQAPTQILKWPQPWALGQVVTKTMVNTVVANASFTYLTALTDSNIVAIWGRM
What is the function of this protein?
Required for G1/S transition.  Recruits and stabilizes the origin recognition complex (ORC) onto chromatin during G1 to establish pre-replication complex (preRC) and to heterochromatic sites in post-replicated cells.  Binds a combination of DNA and histone methylation repressive marks on heterochromatin.  Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3 in a cooperative manner with DNA methylation.  Required for silencing of major satellite repeats.  May be important ORC2, ORC3 and ORC4 stability.
What are the official names of this protein?
Leucine-rich repeat and WD repeat-containing protein 1, Centromere protein 33, CENP-33, Origin recognition complex-associated protein, ORC-associated protein, ORCA.
What is the protein family that this protein belongs to?
Belongs to the LRWD1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Chromosome, telomere. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore. Note=Localizes to heterochromatin during G1 phase. Restricted to centromeres or telomeres as cells progress though S phase. When cells enter mitosis, relocalizes to centromeres. Recruitment to pericentric heterochromatin largely depends on the presence of H3K9me3.
Protein: NTCP_HUMAN
Sequence: MEAHNASAPFNFTLPPNFGKRPTDLALSVILVFMLFFIMLSLGCTMEFSKIKAHLWKPKGLAIALVAQYGIMPLTAFVLGKVFRLKNIEALAILVCGCSPGGNLSNVFSLAMKGDMNLSIVMTTCSTFCALGMMPLLLYIYSRGIYDGDLKDKVPYKGIVISLVLVLIPCTIGIVLKSKRPQYMRYVIKGGMIIILLCSVAVTVLSAINVGKSIMFAMTPLLIATSSLMPFIGFLLGYVLSALFCLNGRCRRTVSMETGCQNVQLCSTILNVAFPPEVIGPLFFFPLLYMIFQLGEGLLLIAIFWCYEKFKTPKDKTKMIYTAATTEETIPGALGNGTYKGEDCSPCTA
What is the function of this protein?
(Microbial infection) Acts as a receptor for hepatitis B virus.
What are the official names of this protein?
Hepatic sodium/bile acid cotransporter, Cell growth-inhibiting gene 29 protein, Na(+)/bile acid cotransporter, Na(+)/taurocholate transport protein, Sodium/taurocholate cotransporting polypeptide, NTCP, Solute carrier family 10 member 1, SLC10A1.
What is the protein family that this protein belongs to?
Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RECA_AGRRK
Sequence: MSQNSLRLVEDKSVDKSKALEAALSQIERSFGKGSIMKLGSNENVVEIETVSTGSLSLDIALGIGGLPKGRIVEIYGPESSGKTTLALQTIAEAQKKGGICAFVDAEHALDPVYARKLGVDLQNLLISQPDTGEQALEITDTLVRSGAIDVLVVDSVAALTPRAEIEGEMGDSLPGLQARLMSQALRKLTASISKSNTMVIFINQIRMKIGVMFGSPETTTGGNALKFYASVRLDIRRIGAVKEREEVVGNQTRVKVVKNKMAPPFKQVEFDIMYGEGVSKTGELVDLGVKAGIVEKSGAWFSYNSQRLGQGRENAKLFLRDNPDLAREIELSLRQNAGLIADRFLQNGGPDADDGEAAAE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XBP1_RAT
Sequence: MVVVAAAPSAASAAPKVLLLSGQPASGGRALPLMVPGPRAAGSEASGTPQARKRQRLTHLSPEEKALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLQLENQLLREKTHGLVIENQELRTRLGMNALVTEEVSEAESKGNGVRLVAGSAESAALRLRAPLQQVQAQLSPPQNIFPWILTLLPLQILSLISFWAFWTSWTLSCFSNVLPQSLLIWRNSQRSTQKDLVPYQPPFLCQWGPHQPSWKPLMNSFVLTMYTPSL
What is the function of this protein?
Acts as a weak transcriptional factor.  Together with HDAC3, contributes to the activation of NFE2L2-mediated HMOX1 transcription factor gene expression in a PI(3)K/mTORC2/Akt-dependent signaling pathway leading to EC survival under disturbed flow/oxidative stress.  Binds to the ER stress response element (ERSE) upon ER stress.  Binds to the consensus 5'-GATGACGTG[TG]N(3)[AT]T-3' sequence related to cAMP responsive element (CRE)-like sequences.  Associates preferentially to the HDAC3 gene promoter region in a static flow-dependent manner.  Binds to the CDH5/VE-cadherin gene promoter region.
What are the official names of this protein?
X-box-binding protein 1, Hepatocarcinogenesis-related transcription factor, HTF.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus. Endoplasmic reticulum. Note=Colocalizes with ERN1 and KDR in the endoplasmic reticulum in endothelial cells in a vascular endothelial growth factor (VEGF)-dependent manner. Colocalizes in the nucleus with SIRT1. SUBCELLULAR LOCATION: [Isoform 1]: Nucleus. Cytoplasm. Endoplasmic reticulum membrane; Single-pass type II membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein. Membrane; Peripheral membrane protein. Note=Shows no preferential localization to either the nucleus or the cytoplasm. Shuttles between the nucleus and the cytoplasm in a CRM1-dependent manner. Localizes predominantly at the endoplasmic reticulum membrane as a membrane-spanning protein; whereas may be only marginally localized on the cytosolic side of the ER membrane as a peripheral membrane.
Protein: RIMM_YERPS
Sequence: MSKQLNPAVPDQPIVLGKMGSTYGIRGWLRVFSSTENAESIFDYQPWFIQQAGKWQHVELEDWKRHSQDLIIKVKGVDDRDAANLLTNCEIFVDSTQLPALEEDDYYWKDLMGCQVVTTTGYELGKIIDMMETGSNDVMVVKANLKDAFGMKERLVPFLHGQVIKKVDLTAQRVEVDWDPGF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_PROMT
Sequence: MSRYVFTSESVTEGHPDKICDQVSDAVLDACLSEDPTSRVACEAVVNTGLCLITGEITSKAEVDFNKLVREVIKNIGYRSASDGGFDANSCAVLVALDQQSSDIAQGVNEAEDHSTDPLDQVGAGDQGIMFGFACDETPELMPLPISLAHRLARRLALVRHQQLIDYLLPDGKTQVSVSYENGVPCSIDTILISTQHKSEVDGITLEEEIQKRIAKDLWKFVVEPATEDLPLKPAKGSTRFLVNPTGKFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFSGKDPTKVDRSAAYAARFVAKALVAANLAKKVEVQLSYAIGVAKPISILVDSFGTGKVSDSELTQLVQDQFDLRPGAIIKAFDLQNLPSIRGGRFYRDTAAYGHFGRTDILLPWEDVSQKAKELSLLK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVD_XANAC
Sequence: MPEYRSKTSTHGRNMAGARALWRATGMRDGDFHKPIIAIANSFTQFVPGHVHLKDLGQLVAREIERVGGVAKEFDTIAVDDGIAMGHDGMLYSLPSREIIADSVEYMVNAHCADALVCISNCDKITPGMLMAALRLNIPTVFVSGGPMEAGKTKLAEHKLDLIDAMVIAADDSASDEKVAEFERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGTVVATHADREQLFLRAGRVAVELCHRWYGGEDPTALPRGIATFEAFENAMTLDIAMGGSTNTILHLLAAAQEGEVAFGMQDIDRLSKRVPQLCKVAPNTPKYHIEDVHRAGGIMAILGELARGGLLHTNAATVHARTLADAIAQWDVTQTDDENVHTFYKAGPAGIPTQIAFSQATRWDSLDTDRSDGCIRDVAHAFSQEGGLAVLYGNIARDGCVVKTAGVDESIHVFEGTARVFESQDAAVKGILADEVVAGDVVVIRYEGPKGGPGMQEMLYPTSYLKSKGLGKQCALLTDGRFSGGTSGLSIGHASPEAAAGGAIGLVREGDRILIDIPNRSINLLISDEELALRRAEQDAKGWKPVEVRPRKVTTALKAYALLATSADKGAVRDKALLDG
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: MURD_PROM9
Sequence: MIDNNHLRKRKNINLVIGLGKSGVWAAKYLRSIDKRVIIWESKDGKEFLEIKTELEELNILVSLNKEFVFKEIHPFIKEIESVVVSPSIPYDHETIIKLKKKGIKVIGEINVAWEILKETNWIGITGTNGKTTVTHLLSHILCENKLYAPFAGNIGTPLCKYAYSKKYEKIDWVVAELSSYQIEISPEVKPNIGIWTTFTEDHLERHKTLENYFNIKKSLLEKSDFRIYNYDDKNLRNHYSSLSKGVWITTSLDKSNFIQCDYWIDDQAFIIERGKRLFKLEHFSLKGIHNLQNLLLVIAAARKVGLSGKKIKDSLSNYKQLPHRMETIYKNNDLEIINDSKATNFDSSIAGINSIEGQIIIISGGRLKGNKYSEWVQVLKQKVKCIFLFGESSKVLKMALINEGFKKDIFEFSELKELLNFVFHYLQNNKVGTLLFSPSCSSFDQFKNYEERGDHFKKLISEKLKVN
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YPI1_YEAST
Sequence: MSGNQMAMGSEQQQTVGSRTVSVEEVPAVLQLRATQDPPRSQEAMPTRHNVRWEENVIDNENMNKKKTKICCIFHPQNEDEEECNHHSDDDGSSSSGSSSSESENEKDLDFNERRQRRLERRHRKLEKKRSYSPNAYEIQPDYSEYRRKQQEKKD
What is the function of this protein?
Regulator of type 1 phosphatases which maintains protein phosphatase activity under strict control.  Regulates the nuclear localization of type 1 phosphatase GLC7 and SDS22, and is involved in the regulation of mRNA 3'-end processing.  May also regulate the activity of type 1 phosphatase PPZ1.
What are the official names of this protein?
Type 1 phosphatases regulator YPI1.
What is the protein family that this protein belongs to?
Belongs to the YPI1 family.
Protein: PDXJ_BORPD
Sequence: MIELGVNIDHVATLRQQRHTVYPDPVQAALRAEDAGADLITLHLREDRRHILDADVHAIRPLLRTRMNLECAITPEMLDIACAVRPSDVCLVPEKRTELTTEGGLEVAGALDAVRDAVARLHDAGIRVSLFIDPDIAQIQAAAQAGATVIELHTGAYAEAPDGQAGPELDRLRAALAEGLRHGMRVNAGHGLHYGNVAPIAALDGIAELNIGHAIVAQAVFDGWEKAVRDMKALMVQARQQALRGR
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBS_ZANAE
Sequence: MASSMMVSTAAVSRTSPAQSNMVVPFAGLHSSAAFPVTRKFADSSKLPSNGLRVRCMQVWPPEGKKKFETLSYLPPLTREQLGQEVDYLIRNGWIPCIEFCKVGFVYREYHNSPGYYDGRYWTMWKLPMFGCTDSSQVLKEVDECSKAYPDYFNRIIGFDNTRQVQCISFLTYKPEGN
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, chloroplastic, RuBisCO small subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MNMG_LACPL
Sequence: MTEVKQYPGRDYDVIVVGAGHAGSEAALAAARMGNRTLLMTINLDMVAFMPCNPSVGGPAKGIVVREIDALGGEMGRNIDKTYVQMRMLNTGKGPAVRALRAQADKHAYHAEMKHTIEREPNLTLRQGIVDGLIVEDGVCKGVITNTGARYSAKSVVLTTGTAARGKIIIGELMYSSGPNNSQPAMKLSGDLERLGFNLERFKTGTPPRVDGNTIDYSVTEEQPGDPEPHHFSFETKDADYIDLKHQLSCWLTYTNETTHKIIRENLDRAPMFTGVIEGVGPRYCPSIEDKIVRFADKKRHQLFLEPEGRNTDEWYVQGLSTSMPEEVQQRILHSIKGLEDAEMMRPGYAIEYDVVAPYQLKATLETKLVKNLYTAGQTNGTSGYEEAAGQGLIAGINAGLRALDRGQFTLKRSDAYIGVMIDDLVTKGTNEPYRLLTSRAEYRLILRHDNADLRLTDKGRELGLIDDERYAAFEAKRQAIKNELDRLGKIRIKPNDEVNAFLRAHNSGELKDGVLAADFLKRPEVQYADLMKFIPAAPEPLERHVIEQVEIQIKYAGYIQKAEERVDRLKKMEAKKIPDRIDYDAIDGLATEAHQKLKKIQPTTIAQASRISGVNPADIAILSVYIQQGRIAKVQ
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FETUB_RAT
Sequence: MGVLRLLVLCTLAACCVARSPPAPPLPNAPFAPLRPLGCNDSEVLAVAGFALQNINRVQKDGYMLTLNRVHDARVHRQEDMGSLFYLMLDVLETGCHVLSRKALKDCGPRIFYETVHGQCKAMFHVNKPRRVLYLPAYNCTLRPVSKRKIHSMCPDCPHPVDLSAPSVLEAATESLAKFNSENPSKQYALVKVTKATTQWVVGPSYFVEYLIKESPCTQSQDSCSLQASDSEPVGLCQGSLIKSPGVPPQRFKKTVTVSCEFFESQDQVPGGENPADTQDAKKLPQKNTAPTSSPSITAPRGSIQHLPEQEEPEDSKGKSPEEPFPVQLDLTTNPQGDTLDVSFLYLEPEEKKLVVLPFPGKEQRSPECPGPEKQRTP
What is the function of this protein?
Protease inhibitor required for egg fertilization.  Required to prevent premature zona pellucida hardening before fertilization, probably by inhibiting the protease activity of ASTL, a protease that mediates the cleavage of ZP2 and triggers zona pellucida hardening (By similarity).
What are the official names of this protein?
Fetuin-B, Fetuin-like protein IRL685.
What is the protein family that this protein belongs to?
Belongs to the fetuin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATP8_EMEND
Sequence: MPQLVPFFFVNQVVFAFIVLTVLIYAFSKYILPRLLRTYISRIYINKL
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: HIS3_MYCTU
Sequence: MTLDPKIAARLKRNADGLVTAVVQERGSGDVLMVAWMNDEALARTLQTREATYYSRSRAEQWVKGATSGHTQHVHSVRLDCDGDAVLLTVDQVGGACHTGDHSCFDAAVLLEPDD
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_ENDTX
Sequence: MSTLVVLGTQWGDEGKGKVIHYLAKQADYIVRYQGGNNAGHTLIHENKPFILHLIPSGILFPDKYCLITNGVVVDPKALKEEIAILDKNNISVEKRFFISEQAHIILPYHKLIDGILEEENVKIGTTRRGIGPAYADKVKRIGIRVVDYLEKDVFEDLLEKNLIEKTPILKNSGVDIANLKEEILKDREELSIFLEPFVTDTSIMIANAIKKNKKILFESAQGTMLDLDFGTYPFVTSSNPIAGGVCSGAGVGPTKIDSVLGVVKAYTTRVGEGPFTVELFDEMGKFLREKGAEYGATTGRPRRCGWFDAVVVRHSVRLSGIKHLILTKLDCVEDIDKIKICVAYKYKDKLYKEFPASRTVQKYAEPVYEEMPGFKGKVKGIIDFEKLPLNAQKYVKRLEQLVDAPIDLISLGRKREETIEVRKGVNWF
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.