PharMolix/UniProtQA huggingface dataset:
Protein: APOC4_PAPHA
Sequence: MSLLRNRLQDLPALCLCVLVLACIGACQSEAYEGTPSPPPKLKMSHWSLVMGRMKELLEPVLNRTRDRWQWFWSPSTFRGFMQTYYDDHLRDLGPRTKAWLLKSKESLLNKTHSLCPRIVCGDKDQG
What is the function of this protein?
May participate in lipoprotein metabolism.
What are the official names of this protein?
Apolipoprotein C-IV, Apo-CIV, ApoC-IV, Apolipoprotein C4.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein C4 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS15_FRACC
Sequence: MPLASDVKQKIMSDYATVERDTGSPEVQVAMLTRRISDLTEHLKVHKHDHHSRRGLLLLVGRRRRLLNYLAKTDINRYRALIERLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: ATPD_PROMT
Sequence: MPLLNTVTTPYAEAFLQVAESRNEVDEVVTQAKSILELWNSCPEFSDAMSSPVLEVNQKKAALEKLFSSQVTPSFLNLLKLLADRQRIGLLNSVLERLLEIYREQRNIALATITSASALNEDQQSELLKKVQSIAGTDNLEIDLKVDSELLGGFVVNVGSKVIDASIAGQVRRLGLALAKVS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: CTPC_MYCTU
Sequence: MTLEVVSDAAGRMRVKVDWVRCDSRRAVAVEEAVAKQNGVRVVHAYPRTGSVVVWYSPRRADRAAVLAAIKGAAHVAAELIPARAPHSAEIRNTDVLRMVIGGVALALLGVRRYVFARPPLLGTTGRTVATGVTIFTGYPFLRGALRSLRSGKAGTDALVSAATVASLILRENVVALTVLWLLNIGEYLQDLTLRRTRRAISELLRGNQDTAWVRLTDPSAGSDAATEIQVPIDTVQIGDEVVVHEHVAIPVDGEVVDGEAIVNQSAITGENLPVSVVVGTRVHAGSVVVRGRVVVRAHAVGNQTTIGRIISRVEEAQLDRAPIQTVGENFSRRFVPTSFIVSAIALLITGDVRRAMTMLLIACPCAVGLSTPTAISAAIGNGARRGILIKGGSHLEQAGRVDAIVFDKTGTLTVGRPVVTNIVAMHKDWEPEQVLAYAASSEIHSRHPLAEAVIRSTEERRISIPPHEECEVLVGLGMRTWADGRTLLLGSPSLLRAEKVRVSKKASEWVDKLRRQAETPLLLAVDGTLVGLISLRDEVRPEAAQVLTKLRANGIRRIVMLTGDHPEIAQVVADELGIDEWRAEVMPEDKLAAVRELQDDGYVVGMVGDGINDAPALAAADIGIAMGLAGTDVAVETADVALANDDLHRLLDVGDLGERAVDVIRQNYGMSIAVNAAGLLIGAGGALSPVLAAILHNASSVAVVANSSRLIRYRLDR
What is the function of this protein?
High affinity, slow turnover Mn(2+) transporting ATPase, which is required for virulence.  Controls the Mn(2+) cytoplasmic quota and is involved in the uploading of Mn(2+) into secreted metalloproteins (PubMed:23482562).  Required for tolerance to Zn(2+) and oxidative stress (PubMed:23482562).  Plays a crucial role in the ability to resist zinc poisoning in human macrophages (PubMed:21925112).  Shows a preference for Mn(2+), but Zn(2+), Co(2+) and Cu(2+) can act as alternative substrates although at slower turnover rates (PubMed:23482562).
What are the official names of this protein?
Manganese-exporting P-type ATPase, Cation-transporting P-type ATPase CtpC, Metal-transporting ATPase Mta72.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AIM41_ASHGO
Sequence: MLMNSAARPMLLFRALARRSASSQAYTDALAHLKQDLKKAMLAKDDTKKTTIRSLLATIKNKEIDSRDKPLDHFALHDIYSKLVAQRRESIDGFLKNGRDDLVQKEQLEMQLIQAYMAALPVASAEELAARADAFLHELKSTHGALPLPKVFAQVSWPTVAQDWNASPAAVRSALAAAFKKSS
What are the official names of this protein?
Altered inheritance of mitochondria protein 41, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AIM41 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: DMA_BPT2
Sequence: MLGAIAYTGNKQSLLPELKPHFPKYDRFVDLFCGGLSVSLNVNGPVLANDIQEPIIEMYKRLINVSWDDVLKVIKQYKLSKTSKEEFLKLREDYNKTRDPLLLYVLHFHGFSNMIRINDKGNFTTPFGKRTINKNSEKRFNHFKQNCDKIIFSSLHFKDVKILDGDFVYVDPPYLITVADYNKFWSEEEEKDLLNLLDSLNDRGIKFGLSNVLEHHGKENTLLKEWSKKYNVKHLNKKYVFNIYHSKEKNGTDEVYIFN
What is the function of this protein?
An alpha subtpe methyltransferase that recognizes the double-stranded sequence 5'-GATC-3' and methylates A-2 on both strands (PubMed:12654995) (Probable).  May prevent degradation of viral DNA by the host restriction-modification antiviral defense system.
What are the official names of this protein?
DNA adenine methylase, DNA-(N(6)-adenine)-methyltransferase, Deoxyadenosyl-methyltransferase, Orphan methyltransferase M.EcoT2Dam, M.EcoT2Dam.
What is the protein family that this protein belongs to?
Belongs to the N(4)/N(6)-methyltransferase family.
Protein: RF1_BACC1
Sequence: MLDRLQAVENRYEKLNELLSDPAIISDSNKLREYSKEQSDIQETVEVYREYKDVREQLKDAKAMLEDKLDAEMREMVKEEVSELESQEKTLSERLKILLVPKDPNDDKNVIVEVRGAAGGDEAALFAGDLYRMYSRYAEVQGWKTEIIEASYTELGGYKEIIFMINGKGAFAKLKFENGAHRVQRVPETESGGRIHTSTATVAVLPEAEEVEIDIHEKDVRVDTFASSGPGGQSVNTTMSAVRLTHLPTGVVVSCQDEKSQIKNKEKAMKVLRARVYDKFRQEAQAEYDQNRKQAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILQGKLDDFINALVMEDQAQRMEAAE
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRP36_NEUCR
Sequence: MPAVKRKAAPTLGAKLQRRVRPRFEAEPDSDVEGSSDEAPSEEEGGGFHTGSDTEEEEEDEEIEEGSEPGSDDDSDAPSEHGGAGIDASQLSFGALARAQASLGALKKKKKKKGGDEDGSDDDEEKEEPNWKTEIEKGMKAKVEKHHRTNKHAPVETTSKKPVSRRRDFLANEPAKPKSRDPRFAPPGIGGSSGKSVVDEIKARKAYSFLDDYQEDEMKQLRMAIKKTKDANEKEELQRALLSMESKKKARARKDKERELLSEHKKKEKELIKQGKTPFYLKKSEQKKQLLVEQFASMKKSQVDKAIERKRKKIAGKEKKALPLARRTAEDR
What is the function of this protein?
Component of the 90S pre-ribosome involved in the maturation of rRNAs.  Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity).
What are the official names of this protein?
rRNA biogenesis protein rrp-36, Ribosomal RNA-processing protein 36.
What is the protein family that this protein belongs to?
Belongs to the RRP36 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: YCIB_BURP6
Sequence: MKFLFDLFPIILFFAAFKLWGIFTATAVAIAATLAQVAWVAFRHRKVDTMLWVSLGVIVVFGGATLVLHDEKFIQWKPTVLYWLFAVGLVAARYAFGKNLIEKMMGKQLTLPEPVWDKLNLAWAAFFAALGVTNLYVVRNFTESQWVNFKLFGTTGAIVVFVILQSLWLAKYLKEE
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VATF_CLOBA
Sequence: MFKKIGVVGDKDSVLAFKALGIDVFPVVGNEEAKKTVDKLAKNDYAVVFVTEHVAQGIEETIERYNKEVLPAVILIPSNQGTLNIGMQRISDNVEKAVGVNIL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit F, V-ATPase subunit F.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase F subunit family.
Protein: ISPF_BURP6
Sequence: MDFRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHFSDTDPRFKGADSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALVVREAAA
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: PSBM_SOLLC
Sequence: MEVNILAFIATALFILVPTAFLLIIYVKTVSQND
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface.
What are the official names of this protein?
Photosystem II reaction center protein M, PSII-M.
What is the protein family that this protein belongs to?
Belongs to the PsbM family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CPSD_STRPN
Sequence: MPTLEIAQKKLEFIKKAEEYYNALCTNIQLSGDKLKVISVTSVNPGEGKTTTSINIAWSFARAGYKTLLIDGDTRNSVMLGVFKSREKITGLTEFLSGTADLSHGLCDTNIENLFVVQSGSVSPNPTALLQSKNFNDMIETLRKYFDYIIIDTPPIGIVIDAAIITQKCDASILVTATGEANKRDIQKAKQQLKQTGKLFLGVVLNKLDISVNKYGVYGSYGNYGKK
What is the function of this protein?
Involved in the regulation of capsular polysaccharide biosynthesis.  Autophosphorylation of CpsD attenuates its activity and reduces the level of encapsulation.  May be part of a complex that directs the coordinated polymerization and export to the cell surface of the capsular polysaccharide (By similarity).
What are the official names of this protein?
Tyrosine-protein kinase CpsD.
What is the protein family that this protein belongs to?
Belongs to the CpsD/CapB family.
Protein: RIMO_METCA
Sequence: MKLPRIGFISLGCPKALVDSERIITQLRAEGYAIVPTYQDADLVVVNTCGFIDAAVEESLEAIGEAVAENGKVIVTGCLGERPEEIQARHPAVLKVTGAHAYEEVMNAVHEHLPPLHDPFMDLVPPQGVRLTPRHYAYLKISEGCNHRCSFCIIPALRGDLVSRPIGEVMTEAERLVAAGVKEILVVSQDTSAYGADLGYRTGFWGGRPLRTRFQELARALGDLGVWIRLHYVYPYPHVDEVIPLMAEGRLLPYLDIPFQHASARVLKAMKRPAATENILAAIRRWREVCPELTLRSTFIVGFPGETEDEFRELLDFLEEARLDRVGCFEYSPVKGAAANALPDPVPAEVKAERHARLMEVQERISAARLRTRIGRTETVLVDEVVEEGAVARRRADAPEIDGQVFIDGATHLEVGEFVEATFEDADAHDLWARLAD
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XYL2_NEOFI
Sequence: MSTSTATAQNLSFVLEGIHQVKFEDRPIPELKDPHDVLVNVKFTGICGSDVHYWEHGSIGQFVVKDPMVLGHESSGVISKVGSAVTGLKVGDRVAMEPGIPCRRCEPCKAGKYNLCEKMAFAATPPYDGTLAKFYVLPEDFCYKLPDNISLQEGALMEPLGVAVHIVRQASVTPGQSVIVFGAGPVGLLCCAVAKAFGAAKIIAVDIQKPRLDFAKRYAATSTFEPAKVSAVDNADRLRKENNLGVGADVVIDASGAEPSVHTGIHVLRPGGTYVQGGMGRSEIMFPIMAACTKELTFKGSFRYGSGDYKLAVGLVASGRVNVKDLITGVVEFHDAEQAFKEVKAGKGIKTLIAGIQD
What is the function of this protein?
Xylitol dehydrogenase which catalyzes the conversion of xylitol to D-xylulose.  Xylose is a major component of hemicelluloses such as xylan.  Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway (By similarity).
What are the official names of this protein?
Probable D-xylulose reductase A, Xylitol dehydrogenase A.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: RIBF_ECO57
Sequence: MKLIRGIHNLSQAPQEGCVLTIGNFDGVHRGHRALLQGLQEEGRKRNLPVMVMLFEPQPLELFATDKAPARLTRLREKLRYLAECGVDYVLCVRFDRRFAALTAQNFISDLLVKHLRVKFLAVGDDFRFGAGREGDFLLLQKAGMEYGFDITSTQTFCEGGVRISSTAVRQALADDNLALAESLLGHPFAISGRVVHGDELGRTIGFPTANVPLRRQVSPVKGVYAVEVLGLGEKPLPGVANIGTRPTVAGIRQQLEVHLLDVAMDLYGRHIQVVLRKKIRNEQRFASLDELKAQIARDELTAREFFGLTKPA
What is the function of this protein?
Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.
What are the official names of this protein?
Bifunctional riboflavin kinase/FMN adenylyltransferase, Riboflavin biosynthesis protein RibF.
What is the protein family that this protein belongs to?
Belongs to the RibF family.
Protein: VAPB7_MYCTU
Sequence: MSMRLAHRLQILLDDECHRRITAVARERGVPVATVVREAIDRGLVSPAGRRKSAGRRLLDAADMSVPEPRELKQELEALRARRG
What is the function of this protein?
Antitoxin component of a possible type II toxin-antitoxin (TA) system.  The cognate toxin is VapC7.
What are the official names of this protein?
Putative antitoxin VapB7.
Protein: SYA_AKKM8
Sequence: MMTATEIRQSFLDFFREKQHTVVPSASLMPQSPGLLFTNAGMNQFVPYFLGVWTPPWTPARATDTQKCIRAGGKHNDLEDVGYDSYHHTFFEMLGNWSFGDYFKREAIRWAWELVVERWGFPAERLYATVYAPDKSKGDPGEFDREAWDFWAELFRSRGLDPDVHIVHGNVKDNFWMMGETGPCGPCSELHVDLTPEGNTKGSLVNKDSDQCIEIWNLVFIQYNAESDGSMRNLPACHVDTGMGFERACSIMQCTNGFKDFSRKPSNYATDVFRPLFDRLEVLSGRKYADVYPAPGSKRVDAEDGTLQEAIAFRVIADHLRTLSFSIADGILPGNNGRNYVLRRILRRAVRYGRRLGFTQPFLAELVDTLVESFGQVFPELAARATTVKEVLNREEASFNETLDRGLELFDAETASAGKVSGEFAFKLYDTYGFPIDLTALLAEERGLDIDMERFNRLMEEQRERARAARKSEVVRALDLKTDAVTEFTGYDVDECAATVLEVSRQGDSLFIITDKTPFYAEMGGQVSDAGLIEIGGESYHVMAVQQIGNARAHVVEARPGLEVKPGDRVHLSIDAERRRRIEAHHTATHLLHCALHQVVSPDAAQQGSFVSEDRLRFDFNSSAVSPDQLRLIEEKVNGWIEESLPVHCTERAYADVKGNAAIAQFFGDKYGDVVRVVQVGGCRDGLDGVSMEFCGGTHIANTKNIGLFKIKSEGAIASGVRRIEAMTGDAALEMIRQHVVAKSLEIAKAVEKIKEVNYELADMGLEQVPVPTIEGKPGLTALGASDIRTVNDSLARFDASVEHFKQTALDAEKKLKKARAGQSAAKADALLNEWLSDAPSSLIQVAEGAGELLQELLNGLKKRQYAGAAFLLCVDSSSLLLGAYCGKDAIADGLSAGDMIREVAALAGGKGGGRADQARGSAPQDADPQALAAAARNIING
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR1_MAGSA
Sequence: MRCPFCGHDDTQVKDSRPTDDNASIRRRRACPACASRFTTSERVQIRDLVVIKKDGSRSTFDRDKVVKSLQIALRKRPVDEEQIERIVNGIHRRLESLGENEVPSKLIGELVMDVLIGMDQVAYLRYASVYRNFREAKDFGDFLGKMGRQGDD
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR 1.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: A85B_MYCS2
Sequence: MTFIDKIRGHWARRMTVAAVAALLLPGLVGVVGGSATAGAFSRPGLPVEYLMVPSPSMGRDIKVQFQSGGPGSHAVYLLDGLRAQDDFNGWDINTNAFEMFLDSGLSVVMPVGGQSSFYSDWYQPACGNNGCVTYKWETFLTSELPEWLAANRDVAATGNAAIGLSMAGSAALILAAYHPDRFIYAGSMSGFLNPSEGWWPFLINISMGDAGGYKANDMWGPTEDPNSAWKRNDPMVQIPRLVANNTRIWVYCGNGQPNELGGGDLPATFLEGLTIRTNETFRDNYIAAGGNNGVFNFPNNGTHNWAYWGRELQAMVPDLQRVLG
What is the function of this protein?
The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein.  They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan and through the synthesis of alpha,alpha-trehalose dimycolate (TDM, cord factor).  They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-trehalose monomycolate (TMM) to another TMM, leading to the formation of TDM (By similarity).
What are the official names of this protein?
Diacylglycerol acyltransferase/mycolyltransferase Ag85B, DGAT, 30 kDa extracellular protein, Acyl-CoA:diacylglycerol acyltransferase, Antigen 85 complex B, 85B, Ag85B, Extracellular alpha-antigen, Fibronectin-binding protein B, Fbps B.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial A85 antigen family.
What are the subcellular locations of this protein?
Secreted.
Protein: QUEA_LACLA
Sequence: MNINDFDFDLPEELIAQTPLEKRSESRLLILDPKTEELEDRHFYNIIDELEAGDALVLNNTRVLPARLHGERAETGGHIELLLLKDMGQNRWETLAKPARKMKVGEEVVFGDGRLKAVVVEVLDHGGRIVEFKYDGIFLEILESLGEMPLPPYIHEQLQDQERYQTVFAKENGSAAAPTAGLHYTPELLEKIADKGVKIVELTLHVGLGTFRPVSVDNVDEHQMHSEFYRLTEEAAAQLRAVKASGHKIVASGTTSIRTLETIGSKFDGDIQADSGWTDIFIKPGYEWKVVDAFNTNFHLPKSTLVMLVAAFAGRDFVLDAYQHAIDEKYRFFSFGDAMFVRPKK
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_DESVV
Sequence: MSEATYQRKGRTLVGIVVSDKNDKTIVVRVETLVKHPLLKKYVRRRKKFTAHDPMNECGIGDKVKIIEFRPLSRNKRWHLESILEKAV
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: DEP2_ALTBR
Sequence: MEDGRSTFKVIIIGAGVTGLTLAHCLAKACIDYVLLDKGIVAPSFGTTITLQPHGCRILHQLGCLDAVLASCDVMSGAQCRDPSGKTFASNDFFRVVKKFTGYDTRTLDRKVFLRTMYEQLPDQSRVHERARVEEIIEDNEKTRVVLQDGQEFVGNLVIGTDGVHSKVREIMWDNANTAKPGMITVEEKRAMVTQYNAIVMACSPVPGLGSHDMEVTSNDKFSFLLLCQPDWISIIVHNKLPEDQQCTWPTRRRYTESDMEALVSRILECPITETVVFGELWKRRLKAQMISLEEGVLEHWFFGRIVLAGDAIHKVTPNSALGGNTAMEDAVTVANTLHTLLAAHPNKKPSTVELQDAFRDNYQNARMDRVRAIVKVGGDLTRQQAYDGWKRYLIQRWLTPIVGLDTLAKNIAGLCVTAPKLSYIDFEEKRGMLNWQDTVAADKELEMHHENVGGVRAEYHKSKWLLTSADWSGGFEAVFPQILGVLMVMWSSVWLFHLAFSRHCISGFGGEVWRTFGADNETSCVAK
What is the function of this protein?
FAD-dependent monooxygenase; part of the gene cluster that mediates the biosynthesis of depudecin, a highly oxidized eleven-carbon linear polyketide that acts as a histone deacetylase (HDAC) inhibitor and makes a small contribution to pathogenesis (PubMed:19737099).  The reducing polyketide synthase DEP5 is the central enzyme in depudecin biosynthesis by yielding the backbone polyketide chain (PubMed:19737099).  The monooxygenases DEP2 and DEP4, as well as the uncharacterized protein DEP1, then act as tailoring enzymes to modify the intermediate polyketide chain into depudecin (PubMed:19737099).
What are the official names of this protein?
FAD-dependent monooxygenase DEP2, Depudecin biosynthesis cluster protein 2.
What is the protein family that this protein belongs to?
Belongs to the paxM FAD-dependent monooxygenase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: SRP54_BUCAP
Sequence: MFNNLTERLSQSLRKIINKGRLTEENIKDTIREVRKALLEADVTLSVIKKFIQNVSKKAIGHEINKSLTPGQEFIKIVKNELILSMGEKNHDLNLSIQPPAIILVVGLQGVGKTTTLVKLAKWIKEKYKKKILTVSTDIYRAAAIKQLQILSDQVKIDFYLSDTTQTPINITKEAIEHAKLKLYDLLLIDTAGRLHINTEMMNEINTIQNISKPIETLLIVDSMMGQDAINIAKKFSASLSISGIVITKTDSDARSGVALSIRHITGKPIKFIGTGEKLHQLEPFHPERIADRILGMNQVISLIKDIEEKVNQSQVKNLTKKFRKGDDFNLNDFLIQLKEMKNMGNLNYFIEKFSKNKILSNNPLLGENKNTLNRIEAIIYSMTHKERMHPIIIKGSRKRRIALGSGTKIQDVNKLLKNFDNIKKIMKKIKKGGIGKMIRNISNILPKNF
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes.  The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.  Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
What are the official names of this protein?
Signal recognition particle protein, Fifty-four homolog.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. SRP54 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=The SRP-RNC complex is targeted to the cytoplasmic membrane.
Protein: DHLA_XANAU
Sequence: MINAIRTPDQRFSNLDQYPFSPNYLDDLPGYPGLRAHYLDEGNSDAEDVFLCLHGEPTWSYLYRKMIPVFAESGARVIAPDFFGFGKSDKPVDEEDYTFEFHRNFLLALIERLDLRNITLVVQDWGGFLGLTLPMADPSRFKRLIIMNACLMTDPVTQPAFSAFVTQPADGFTAWKYDLVTPSDLRLDQFMKRWAPTLTEAEASAYAAPFPDTSYQAGVRKFPKMVAQRDQACIDISTEAISFWQNDWNGQTFMAIGMKDKLLGPDVMYPMKALINGCPEPLEIADAGHFVQEFGEQVAREALKHFAETE
What is the function of this protein?
Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons.  Has a broad substrate specificity, which includes terminally mono- and di- chlorinated and brominated alkanes (up to C4 only).  The highest activity was found with 1,2-dichloroethane, 1,3-dichloropropane, and 1,2-dibromoethane.
What are the official names of this protein?
Haloalkane dehalogenase.
What is the protein family that this protein belongs to?
Belongs to the haloalkane dehalogenase family. Type 1 subfamily.
Protein: ATPB_CHLPM
Sequence: MQEGKISQIIGPVVDVDFPEGQLPAILDALSIAKPDGTKIVLETQQHLGEERVRTVAMESTDGLIRGMAVENTGRPIQAPVGEGVLGRMLNVVGDPIDGRGPVDAKKTYSIHRSAPKFEDLSTKAEMFETGIKVIDLLEPYSRGGKTGLFGGAGVGKTVLIMELINNIAKQQSGYSVFAGVGERTREGNDLWHEMMESGVIDKTALVFGQMNEPPGARARVALTGLSIAEYFRDEENRDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGELQDRITSTKNGSVTSVQAIYVPADDLTDPAPATAFAHLDATTVLSRSIAELGIYPAVDPLDSTSRILDPNIVGDDHYDTAQAVKMILQRYKDLQDIIAILGMDELSDEDKLVVSRARKVQRFLSQPFFVAEAFTGLSGKYVKLEETIKGFKEIIAGKHDNLPENAFYLVGTIEEAIEKAKTL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.