PharMolix/UniProtQA huggingface dataset:
Protein: CYB_EOSRU
Sequence: MTNMRKSHPLLKIINHSLIDLPAPSNISVWWNFGSLLGVCLGLQILTGLFLAMHYTSDTLTAFSSVTHICRDVNYGWIIRYLHANGASMFFICLFLHVGRGMYYGSYSYLETWNIGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYVGTSLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVIVHLLFLHETGSNNPTGLNSNADKIPFHPYYTIKDILGFIVMFLFLMILVLFSPDMLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSILVLVLLPLLHTSAQRSLMFRPISQCLFWILVADLFTLTWIGGQPVEHPFIIIGQLASILYFLIILGLMPLAGILENKIMKI
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RGMG_ALBFT
Sequence: MTSLISVKNLSKSFPGVKALDQVHFDLRAGEVHALMGENGAGKSTLMKILAGVYRKDSGEMLLDGQPVEIESPAHAQSLAIGIVHQELHLMNHLTAAQNIYLGREPRHCGGLFLDEARLNQDTQILFDRLNLALAPTTAIGELTVARQQMVEIAKALSFKSRVLIMDEPTAALNNAEIDELFRIIRQLKSEGVGIVYISHKMDEIQRIADRITVMRDGSTIGTVPASTPMQQVIAMMVGRNLEQAEKHIPDTSANEVLLEVRGLNRGRVIRDVNFSVRRGEILGFAGLMGAGRTEVARAVFGADPIDSGEVRVRGELIRLASPQDAVQAGIGYLSEDRKHFGLATGMDVESNITLPSLKRWLKWGLFLNQPAIHHISQQMVGKLRIKTPSLTQTARLLSGGNQQKVVVAKWLVQDCDVLIFDEPTRGIDVGAKSEIYKLLNELATQGKAIIVISSELPEVLLLSHRVLVMCEGRITGEVAGDVATQETLMALATRRESLASTVH
What is the function of this protein?
Part of an ABC transporter complex involved in carbohydrate import.  Could be involved in ribose, galactose and/or methyl galactoside import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Putative ribose/galactose/methyl galactoside import ATP-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Carbohydrate importer 2 (CUT2) (TC 3.A.1.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: THOC7_BOVIN
Sequence: MGAVTDDEVIRKRLLIDGDGAGDDRRINLLVKSFIKWCNSGSQEEGYSQYQRMLSTLSQCEFSMGKTLLVYDMNLREMENYEKIYKEIECSIAGAHEKIAECKKQILQAKRIRKNRQEYDALAKVIQHHPDRHETLKELEALGKELEHLSHIKESVEDKLELRRKQFHVLLSTIHELQQTLENDEKLSEVEEAQEASMETDPKP
What is the function of this protein?
Required for efficient export of polyadenylated RNA.  Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA.  TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.
What are the official names of this protein?
THO complex subunit 7 homolog.
What is the protein family that this protein belongs to?
Belongs to the THOC7 family.
Protein: RS16_NOSS1
Sequence: MIKLRLKRFGKKREASYRIVAMNNLSRRDGRPLEELGYYNPRTDEVRLDVPGIVKRLQQGAQPTDTVRRILQKQNVFEQVSAKPAS
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: DNLJ_RHIEC
Sequence: MSTEGSAVETLTIEEAAAELERLAREIAHHDALYHGKDQPEISDADYDALKRRNDALEARFPELIREDSPSRRVGAAPSVTFSPVVHARPMLSLDNTFSQEDVQDFVASVYRFLGRMPDQSIAFTAEPKIDGLSMSIRYENGRLTTAATRGDGTTGENVTANIRTIAEIPNQLPKGVPAVVEIRGEVYMAKSDFLALNRQMEAEGKQTYVNPRNTAAGSLRQLDAKVTASRKLKFFAYAWGEMSDMPADTQFAMVQTFKDWGFPVNPLMKRLNSVADILAHYDEIGLKRPDLDYDIDGVVYKVDSLELQQRLGFRSRSPRWATAHKFPAEQAFTEVEKIEIQVGRTGALTPVARLKPITVGGVVVTNATLHNEDYIKGIGNSGERIRPEEHDIREGDTVIVQRAGDVIPQILDVVMEKRLAEVKPYEFPKICPVCGSHAVREVNEKTGKMDSVRRCTGGFICRAQATEHLKHFVSRNAFDIEGLGSKQIDFFFENEDPSLQIRTAPEIFTLEKRQQDSLTKLENIDGFGKVSVGKLYAAINERRSIALHRFIYALGIRHVGETTAKLLARSYGTYEAFATAMKEAAPLSGDAWNDLNAIEGIGEVVARAMVEFYKEPRNVEVIGRLLDEVTPAEAEQPVTAGSPVAGKTVVFTGSLEKFTRDEAKARAESLGAKVAGSVSKKTDIVVAGPGAGSKLDKARELGVQTMDEDEWLALISG
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: RS15_XANAC
Sequence: MSVDTQKVIEDNKRSAQDTGSPEVQVALLTARIELLTGHFKTHKKDHHSRRGLLQMVNRRRSLLDYLKKKDNERYKSLIEKLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: TSAD_BRUA1
Sequence: MRVLGIETSCDETAAAIVERDDMGEGRILSNVVLSQIAEHEPYGGVVPEIAARAHVEALDRLVDRALNDAGLKLYEVDAVAATAGPGLIGGLIVGLMTAKALAMAAQKPFYAVNHLEGHALTARLTDGLPFPYLLLLVSGGHTQMVLVRGIGDYERLGTTIDDALGEAFDKTAKLLGLPYPGGPTVERMALQGDQKRFALPRPLKGEARLDFSFSGLKTAVRQTATELVPLTDQDVTDICASFQAAVADTLSDRVGRSLERFKTEFPDCATPSLVVAGGVAANKTLRAALENLCTRHGFAFIAPPLNLCTDNAAMIAWAGAERAATQAPDSLDIAPRSRWPLDEKSAPVFGTGRRGAKA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL41_GOSHI
Sequence: MRAKWKKKRMRRLKRKRRKMRQRSK
What are the official names of this protein?
60S ribosomal protein L41.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL41 family.
Protein: SYS_CAMJE
Sequence: MLDLKNLQNNFDEVAKKLKNKKVDENILKKLAELFASLKKEKIALEEFQAFQNKFSKELATAEDKESLKAKLSENKSKINEQSAKVNALENELEEIAHAIPNIPDECVPVGEDENENVELKKVLNPPSFDFTPKEHFELGESLNWLDFMRGVKISQSRFCVLKNEGALLSRALVNYMIDFNRSRGFEFVNVPFLVNGATMFGTGQLPKFKEDMYKVDDEDLYLISTSEIPVTNLYSGEILASETLPIKMTCYSACFRKEAGSAGRDTRGIIRQHQFEKVELVSITKPEQSDSVFNEMLECASDLLSSLGLAHRHLMLCTGDLGFSAAKTVDLEVWLPGQNKYREISSVSNCRDFQARRAKIRYKNEQGKNELVHTLNGSSLAVGRTLVAIMENYQDKEGKIHIPDVLKKYF
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VORB_METTH
Sequence: MATQMVKGNTAVIIGAMYAGCDCYFGYPITPASEILHEASRYFPMVGRKFVQAESEEAAINMVYGAAAAGHRVMTASSGPGISLKQEGISFLAGAELPAVIVDVMRAGPGLGNIGPEQGDYNQIVKGGGHGNYRNMVLAPSSVQEMCDLTMEAFELADKYRNPVVVLTDAVLGQMAEPLRFPEEAVEHRPDTSWAVCGNRETMKNLVTSIFLDFDELEEFNFYLQEKYARIEENEVRYEEYLVDDAEIVMVAYGISSRVARSAVETARAEGINVGLLRPITLFPFPSDRIRELADGGCRFISVEMSSGQMREDIRMASGCRDVELVNRMGGNLIELRDVLEKIREVAGDSSD
What are the official names of this protein?
Ketoisovalerate oxidoreductase subunit VorB, VOR, 2-oxoisovalerate ferredoxin reductase subunit beta, 2-oxoisovalerate oxidoreductase beta chain.
Protein: TMN10_ARATH
Sequence: MAKVRILIFTLVLFFSLNVHIHGFYLPGVAPQDFQMGDALMVKVNKLTSTKTQLPYSYYSLPYCRPEHIVDSAENLGEVLRGDRIENSPFVFKMRESQMCAAVCRVKLDKKTAKAFKEKIADEYRVNMILDNLPLVVPVQRPDQDNVVVYQHGFHVGLKGIFAGKKEEKYFIHNHLTFTVRYHRDIQTDSSRIVGFEVKPFSVKHEYEGQWNEKARLTTCDPHTKRAVTNSESPQEVEEGNEIIFTYDVDFQESEVKWASRWDTYLLMADDQIHWFSIVNSMMIVLFLSGMVAMIMLRTLYRDISNYNQLESHEEALEETGWKLVHGDVFRPPTNPELLCVYAGTGVQCFGMILVTMIFACLGFLSPSNRGGLMTAMLLLWVFMGLLAGYASSRLYKTLRGTEWKRNALKTAFMFPATVFVAFFVLNAIIWGQKSSGAVPFGTMFALVVLWFGISVPLVFIGGYIGFRKPAPEDPVKTNKIPRQIPTQAWYMNPIFSILIGGILPFGAVFIELFFILTSIWLHQFYYIFGFLFIVFIILIITCAEITVVLCYFQLCSEDYQWWWRSYLTSGSSAVYLFLYAVFYFYTKLEITKLVSAVLYFGYMLIVSYVFFVFTGAIGFYACFWFTRLIYSSVKID
What are the official names of this protein?
Transmembrane 9 superfamily member 10, Endomembrane protein 3, Transmembrane nine protein 10, AtTMN10.
What is the protein family that this protein belongs to?
Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
What are the subcellular locations of this protein?
Endosome membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: CDC42_HUMAN
Sequence: MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPPEPKKSRRCVLL
What is the function of this protein?
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.  In active state binds to a variety of effector proteins to regulate cellular responses.  Involved in epithelial cell polarization processes.  Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase (PubMed:15642749).  Regulates cell migration (PubMed:17038317).  In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (PubMed:14978216).  Required for DOCK10-mediated spine formation in Purkinje cells and hippocampal neurons.  In podocytes, facilitates filopodia and podosomes formation upon DOCK11-activation (PubMed:33523862).  Upon activation by CaMKII, modulates dendritic spine structural plasticity by relaying CaMKII transient activation to synapse-specific, long-term signaling (By similarity).  Also plays a role in phagocytosis through organization of the F-actin cytoskeleton associated with forming phagocytic cups (PubMed:26465210).
What are the official names of this protein?
Cell division control protein 42 homolog, G25K GTP-binding protein.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Midbody. Cell projection, dendrite. Note=Localizes to spindle during prometaphase cells. Moves to the central spindle as cells progressed through anaphase to telophase (PubMed:15642749). Localizes at the end of cytokinesis in the intercellular bridge formed between two daughter cells (PubMed:15642749). Its localization is regulated by the activities of guanine nucleotide exchange factor ECT2 and GTPase activating protein RACGAP1 (PubMed:15642749). Colocalizes with NEK6 in the centrosome (PubMed:20873783). In its active GTP-bound form localizes to the leading edge membrane of migrating dendritic cells (By similarity).
Protein: AF121_ALTAL
Sequence: MVVHSLGSTNLQENQSAVGAIAAWRLQHAGYSRVTTLCRSNYDAVKTSGFRLSTSLWGKHIYKPDRVANDIREVKHTEFDYVVDATKNISATWTLSISEIRQVVRPRTTILSLQNGMQPERRFTKAFPANTVLAGICFLSCSQISPGCILQTSHIRPHAFYIGMSSSPSFRDAKQKLRRLVSLDSSFLAVRDIRIQQWIKLITNVTFNSATALMNAHTRDVLDSASGIELVRALAEECYELGLALGMAIPQGTVDSIIEDFLSAPPVVTSMLQDLRAGRPLELDALLGKLKTYLVIL
What is the function of this protein?
Oxidoreductase; part of the gene clusters that mediate the biosynthesis of the host-selective toxins (HSTs) AF-toxins responsible for Alternaria black spot of strawberry disease by the strawberry pathotype (Ref. 1).  AF-toxin I and III are valine derivatives of 2,3-dyhydroxy-isovaleric acid and 2-hydroxy-isovaleric acid respectively, while AF II is an isoleucine derivative of 2-hydroxy-valeric acid (PubMed:15066029, Ref. 1, PubMed:22846083).  These derivatives are bound to a 9,10-epoxy-8-hydroxy-9-methyl-decatrienoic acid (EDA) moiety (PubMed:15066029, Ref. 1, PubMed:22846083).  On cellular level, AF-toxins affect plasma membrane of susceptible cells and cause a sudden increase in loss of K(+) after a few minutes of toxin treatment (PubMed:22846083).  The aldo-keto reductase AFTS1 catalyzes the conversion of 2-keto-isovaleric acid (2-KIV) to 2-hydroxy-isovaleric acid (2-HIV) by reduction of its ketone to an alcohol (PubMed:15066029).  The acyl-CoA ligase AFT1, the hydrolase AFT2 and the enoyl-CoA hydratases AFT3 and AFT6, but also the polyketide synthase AFT9, the acyl-CoA dehydrogenase AFT10, the cytochrome P450 monooxygenase AFT11 and the oxidoreductase AFT12 are all involved in the biosynthesis of the AK-, AF- and ACT-toxin common EDA structural moiety (PubMed:12019223, Ref. 1, PubMed:18986255).  The exact function of each enzyme, and of additional enzymes identified within the AF-toxin clusters have still to be determined (PubMed:12019223, Ref. 1, PubMed:18986255).
What are the official names of this protein?
Oxidoreductase AFT12-1, AF-toxin biosynthesis protein 12-1.
What is the protein family that this protein belongs to?
Belongs to the ketopantoate reductase family.
Protein: CAD13_HUMAN
Sequence: MQPRTPLVLCVLLSQVLLLTSAEDLDCTPGFQQKVFHINQPAEFIEDQSILNLTFSDCKGNDKLRYEVSSPYFKVNSDGGLVALRNITAVGKTLFVHARTPHAEDMAELVIVGGKDIQGSLQDIFKFARTSPVPRQKRSIVVSPILIPENQRQPFPRDVGKVVDSDRPERSKFRLTGKGVDQEPKGIFRINENTGSVSVTRTLDREVIAVYQLFVETTDVNGKTLEGPVPLEVIVIDQNDNRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFYIDPEKGDIVTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKEFQATVEEGAVGVIVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGPSSTATVHITVLDVNEGPVFYPDPMMVTRQEDLSVGSVLLTVNATDPDSLQHQTIRYSVYKDPAGWLNINPINGTVDTTAVLDRESPFVDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAPFIYPTVAEVCDDAKNLSVVILGASDKDLHPNTDPFKFEIHKQAVPDKVWKISKINNTHALVSLLQNLNKANYNLPIMVTDSGKPPMTNITDLRVQVCSCRNSKVDCNAAGALRFSLPSVLLLSLFSLACL
What is the function of this protein?
Cadherins are calcium-dependent cell adhesion proteins.  They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.  May act as a negative regulator of neural cell growth.
What are the official names of this protein?
Cadherin-13, Heart cadherin, H-cadherin, P105, Truncated cadherin, T-cad, T-cadherin.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: KAD6_METTH
Sequence: MICITGTPGVGKTTLAGILRERGLEVISLGELIRQKGFVLGRDPIRGYLEADIEAACSHLQEMEGLDVVEGHLSHLCRSCSMVIVLRLHPEVLRGRLEGRGYPEGKVLENLEAEALDVCTVEAFEIHGERVHEVDTTGRSPHEVADIITDIMNGSRVCPPGGVDFSGWLLG
What is the function of this protein?
Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.
What are the official names of this protein?
Putative adenylate kinase, AK, ATP-AMP transphosphorylase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family. AK6 subfamily.
Protein: PCID2_XENLA
Sequence: MAHITINQYLQQVQEAIDSKDGFNCADLVSFKHPHVANARLQLLSPEEKCQQVLEPPYDEMFAAHLRCINAASNHDFVEAYKYQTLVVQSFLKSFQAHKEENWALPIMYSITLDLRIFANNADQQLVKKGKGKVGDMLEKAAEILMSCFRVCASDTRAAFEDSKKWGMLFLVNQLFKIYFKISKLHLCKPLIRAIDSSNFKEEYTMAQRVTFKYYVGRKSMFDSDFKKAEEYLSFAFEHCHRSSQKNKRMILIYLLPVKMLLGHMPTIHLLKKYDLMQFAEVTKAVSEGNLLLLTEALTKHETFFIRCGIFLILEKLKIISYRNLFKKVYLLLKTHQLSLDAFLVALKFMEVGDVDIDEVQCIIANLIYMGHIKGYISHQHQKLVVSKQNPFPPLSTVC
What are the official names of this protein?
PCI domain-containing protein 2, CSN12-like protein.
What is the protein family that this protein belongs to?
Belongs to the CSN12 family.
Protein: AROE_BACMK
Sequence: MKQLYGVIGNPIGHSLSPVMHNDAFEHLNMDAHYLAFLVEEEALGEAVKGLKALGISGFNVTTPHKVAIMEYLDEIAPLARQIGAVNTVVHRDGKLIGYNTDGIGFVRALQSISEDPLQEKRILLIGAGGASRAIYFSLADVGVKEIDIANRTRDKAKNLISGCMENVNSHALSLECAAENQGEYDIIIQTTTIGMHPHVEYTPLEIRSLKQGTIVSDIIYNPFETKILGDAKEQGAIIQNGIDMFVYQGALAFEMWTGCVPNIDRMKQLVMRELGG
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: ACPS_MYCGA
Sequence: MIIGVGIDVVSIDRFQAKKSDEFIKKLLTEHEQNKYKTVIGESNQNIFLAIRWSLKEAIFKALKTWDEFTQLEIRKIHGAYECSLNEKIKLHLSISHEGQRLVAMAVAERI
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAGA_VIBCH
Sequence: MYALTNCKIYTGNDVLVKHAVIINGDKIEAVCPIESLPSEMNVVDLNGANLSPGFIDLQLNGCGGVMFNDEITAETIDTMHKANLKSGCTSFLPTLITSSDENMRQAIAAAREYQAKYPNQSLGLHLEGPYLNVMKKGIHSVDFIRPSDDTMIDTICANSDVIAKVTLAPENNKPEHIEKLVKAGIVVSIGHTNATYSEARKSFESGITFATHLFNAMTPMVGREPGVVGAIYDTPEVYAGIIADGFHVDYANIRIAHKIKGEKLVLVTDATAPAGAEMDYFIFVGKKVYYRDGKCVDENGTLGGSALTMIEAVQNTVEHVGIALDEALRMATLYPAKAIGVDEKLGRIKKGMIANLTVFDRDFNVKATVVNGQYEQN
What is the function of this protein?
Involved in the first committed step in the biosynthesis of amino-sugar-nucleotides.  Catalyzes the hydrolysis of the N-acetyl group of N-acetylglucosamine-6-phosphate (GlcNAc-6-P) to yield glucosamine 6-phosphate and acetate.
What are the official names of this protein?
N-acetylglucosamine-6-phosphate deacetylase, GlcNAc 6-P deacetylase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. NagA family.
Protein: BIOB1_FRACC
Sequence: MTASVTTSVTAHPTAPAPASQRPPADQDGADILTVARREVLDGGRGLDEAGVLAVLRLPDETLTDLLALAHEVRMRWCGPEVEVEGIVSLKTGGCPEDCHFCSQSGKFDSPVRSAWLDVPSLVDAARQTAATGATEFCIVAAVRGPDARLMAQVREGVAAIRAAVDINVACSLGMLTSEQVDELTAMGVHRYNHNLETARSHFPNVVTTHSWEERWETCEMVRAAGMELCCGAILGVGESLEQRAELATQLAALEPDEVPLNFLNPRPGTPFGDLPLVEPRDALRAIAAFRLAMPRTILRYSGGREITLGDLDVQGMLGGINAMIVGNYLTTLGRSAEADLKMLAELSMPIKSLQATL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase 1.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: THIG_ANADF
Sequence: MADTWSIGAHTFTSRLLVGTGKYPDFTTMQRALVASGAEVVTVAVRRLELSKSGEASLLEWIPKGMKLLPNTAACFTAEEAIRTARLGRELEMGDLVKLEVIGDRRTLFPDVEGLVAAAKVLVKEGFTVLPYTNDDPVTAKKLEDAGCAAVMPLGAPIGSGLGIRNPYNLRIIMETVKVPVLVDAGVGTASDAAVAMELGAVAVLMNTAIAEARDPVLMAEAMRAGVEGGRKAYLAGRIPTKLHASASSPMTGLIGT
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_ECO8A
Sequence: MAVVKCKPTSPGRRHVVKVVNPELHKGKPFAPLLEKNSKSGGRNNNGRITTRHIGGGHKQAYRIVDFKRNKDGIPAVVERLEYDPNRSANIALVLYKDGERRYILAPKGLKAGDQIQSGVDAAIKPGNTLPMRNIPVGSTVHNVEMKPGKGGQLARSAGTYVQIVARDGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAARWRGVRPTVRGTAMNPVDHPHGGGEGRNFGKHPVTPWGVQTKGKKTRSNKRTDKFIVRRRSK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: VATG3_ARATH
Sequence: MDSLRGQGGIQMLLTAEQEAGRIVSAARTAKLARMKQAKDEAEKEMEEYRSRLEEEYQTQVSGTDQEADAKRLDDETDVRITNLKESSSKVSKDIVKMLIKYVTTTAA
What is the function of this protein?
Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase).  V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
What are the official names of this protein?
V-type proton ATPase subunit G3, V-ATPase subunit G3, Vacuolar H(+)-ATPase subunit G isoform 3, Vacuolar proton pump subunit G3.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase G subunit family.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein.
Protein: NDE1B_XENLA
Sequence: MDDLENIIFNSVEEEIIYWKSVAMKYKQCSEEAQQELQEFQEASREYEAELEAQLQQTEGRNRDIFSENNRLRMELDSIKEKYEEQHSENYIQISTLEGDLSTTKAVRDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENVLESVQRLKDEARDLRQELAVQQKQEKPKSNMVSPETERMDTSVQASIAIPLAPLTPLSQRGCASTLNSPLSFKTSWDDGYSGTPLTPCARISALNIVGDLLRKVGALESKLASCRNFVHEQSPNRPLTSVSARMNKTREGIENRLSIASGSSVEKGLIKRLEFGSLPSNTPMQGMRSPQGVVKIII
What is the function of this protein?
Required for centrosome duplication and formation and function of the mitotic spindle.
What are the official names of this protein?
Nuclear distribution protein nudE homolog 1-B.
What is the protein family that this protein belongs to?
Belongs to the nudE family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Localizes to the interphase centrosome and to the mitotic spindle.
Protein: KAD_WOLSU
Sequence: MKKLFLIIGAPGSGKTTDAEIIAKNNPDSINHYSTGELLRAEVASGSERGKIIEGFTSKGNLVPLEIVVETIVSAIKNAPKNVVLIDGYPRSTEQMEALDKILKEESDVELTNVIEVEVSEQVACDRVLGRARGADDNAEVFRNRMSVYLAPLKPIQAFYTAKGILHKINGERTIEEIVSEMEGFIKSRL
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.