PharMolix/UniProtQA huggingface dataset:
Protein: RNPA_ECOSE
Sequence: MVKLAFPRELRLLTPSQFTFVFQQPQRAGTPQITILGRLNSLGHPRIGLTVAKKNVRRAHERNRIKRLTRESFRLRQHELPAMDFVVVAKKGVADLDNRALSEALEKLWRRHCRLARGS
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: RL3_PICTO
Sequence: MATPHHSRRGSMAYYPRVRAKRIQGDIRSWPEIEGQTKVQAFAGYKVGMTHIQMVDYRKNSVTAGQVIMAPVTVVEVPPLTVMSIRYYARGDNGLEVISEEWAENIDKDVLRRINKINRHKKGIEVKDVDDVRLMVHTNPQLVSGVPSKTPEIFEIRIGGSTIENRIKYAKERLGSNISFSDFSKPGNFVDVIAVTKGKGFQGVVKRFGVKLLPRKNRKHRRMIGTLGPWHPDWVRNTVPQAGQVGFHQRTIHNIRIIKFDTKDHVDDINVKGGFLNYGIVRNDYVLLFGSVPGPAKRLIKMRDPARQTRPAVESIEVTYVSRESKQGD
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: TRI35_PONAB
Sequence: MERSPDVSPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSPTCPVCKDRASPADLRTNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQGHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEAAWLEGRIRQEFDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKEDDVSFLMKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASVELPFSFDPNTAAGWLSVSDDLTSVTNHGYRVQVENPERFSSAPCLLGSRVFSQGSHAWEVALGGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDHCVTSDPATSPLVLAIPRRLRVELECEEGELSFYDAERHCHLYTFHARFGEVRPYFYLGGARGAGPPEPLRICPLHISVKEELDG
What is the function of this protein?
E3 ubiquitin-protein ligase that participates in multiple biological processes including cell death, glucose metabolism, and in particular, the innate immune response.  Mediates 'Lys-63'-linked polyubiquitination of TRAF3 thereby promoting type I interferon production via RIG-I signaling pathway.  Can also catalyze 'Lys-48'-linked polyubiquitination and proteasomal degradation of viral proteins such as influenza virus PB2.  Acts as a negative feedback regulator of TLR7- and TLR9-triggered signaling.  Mechanistically, promotes the 'Lys-48'-linked ubiquitination of IRF7 and induces its degradation via a proteasome-dependent pathway.  Reduces FGFR1-dependent tyrosine phosphorylation of PKM, inhibiting PKM-dependent lactate production, glucose metabolism, and cell growth.
What are the official names of this protein?
E3 ubiquitin-protein ligase TRIM35.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Found predominantly in cytoplasm with a granular distribution. Found in punctuate nuclear bodies.
Protein: RBL_GONAR
Sequence: SVGFKAGVKDYKLTYYTPEYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYNIEPVAGEENQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPKSYIKTFEGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEALFKAQAETGEIKGHYLNATAGTCEEMIKRAVCARELGAPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRLSGGDHIHAGTVVGKLEGEREITLGFVDLLRDDFVEKDRSRGIYFTQDWVSLPGVIPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNTIIREASKWSPELAAACEVWKEIKFEFPAMDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: S14L2_MOUSE
Sequence: MSGRVGDLSPKQEEALAKFRENVQDVLPTLPNPDDYFLLRWLRARSFDLQKSEAMLRKHVEFRKQKDIDKIISWQPPEVIQQYLSGGRCGYDLDGCPVWYDIIGPLDAKGLLFSASKQDLLRTKMRDCELLLQECIQQTTKLGKKIETITMIYDCEGLGLKHLWKPAVEAYGEFLTMFEENYPETLKRLFVVKAPKLFPVAYNLIKPFLSEDTRRKIMVLGANWKEVLLKHISPDQLPVEYGGTMTDPDGNPKCKSKINYGGDIPKQYYVRDQVKQQYEHTVQVSRGSSHQVEYEILFPGCVLRWQFMSEGSDVGFGIFLKTKMGERQRAGEMTEVLPNQRYNSHMVPEDGTLTCSEPGIYVLRFDNTYSFIHAKKVSFTVEVLLPDKAAEEKMNQQGADTPK
What is the function of this protein?
Carrier protein.  Binds to some hydrophobic molecules and promotes their transfer between the different cellular sites.  Binds with high affinity to alpha-tocopherol.  Also binds with a weaker affinity to other tocopherols and to tocotrienols.  May have a transcriptional activatory activity via its association with alpha-tocopherol.  Probably recognizes and binds some squalene structure, suggesting that it may regulate cholesterol biosynthesis by increasing the transfer of squalene to a metabolic active pool in the cell (By similarity).
What are the official names of this protein?
SEC14-like protein 2, Alpha-tocopherol-associated protein, TAP.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Cytoplasmic in absence of alpha-tocopherol, and nuclear in presence of alpha-tocopherol.
Protein: NCBP2_XENTR
Sequence: MALGALKSDSYVELSQYRDQHFRGNRSDQECLLKHSCTLYVGNLSFYTTEEQIHELFSKSGDVKKIVMGLDKIKKTACGFCFVEYYTRTDAEQAMRFINGTRLDDRIIRTDWDAGFKEGRQYGRGKSGGQVRDEYRQDYDAGRGGYGKIVQSI
What is the function of this protein?
Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export.  The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore.  The CBC complex is also involved in mediating U snRNA and intronless mRNAs export from the nucleus.  The CBC complex is essential for a pioneer round of mRNA translation, before steady state translation when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E.  The pioneer round of mRNA translation mediated by the CBC complex plays a central role in nonsense-mediated mRNA decay (NMD), NMD only taking place in mRNAs bound to the CBC complex, but not on eIF4E-bound mRNAs.  The CBC complex enhances NMD in mRNAs containing at least one exon-junction complex (EJC), promoting the interaction between upf1 and upf2.  The CBC complex is also involved in 'failsafe' NMD, which is independent of the EJC complex, while it does not participate in Staufen-mediated mRNA decay (SMD).  During cell proliferation, the CBC complex is also involved in microRNAs (miRNAs) biogenesis via its interaction with srrt/ars2, thereby being required for miRNA-mediated RNA interference.  The CBC complex also acts as a negative regulator of parn, thereby acting as an inhibitor of mRNA deadenylation.  In the CBC complex, ncbp2/cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ncbp1/cbp80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure.  The conventional cap-binding complex with NCBP2 binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus (By similarity).
What are the official names of this protein?
Nuclear cap-binding protein subunit 2, 20 kDa nuclear cap-binding protein, NCBP 20 kDa subunit, CBP20.
What is the protein family that this protein belongs to?
Belongs to the RRM NCBP2 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: SIBB_DICDI
Sequence: MKNIIKYLFIFLCFLIITEATHFRYGTISWAPTTKYNNIKITVNLAFRTGYWGSVAIGQQISHGNIDFGDNTKTGLTMTVTSKDTDNEWFTATWSGIHEYSPQPTAQTKNYIVVYKDCCRISTLLNNGDQYWHISAGIQIDSSNAFPNVNWSPVTNMMPIVRVIANKNNNFRIIANDQNKQTALSYKFTDTWTMDQPPGMTVDSINGNCWFLPTKEGLYSTQIKVTDALGAYVVVDFLLQTYTEVGKCDPTCSNADASCTSNSQCTKCSNTGSNSINTCTNIQSPPEFIIPTPKNGETILFPIDKSSEFYLSCKTPYASRTASITTSSIPTELALTTTSTGQTNSIKYSWSPKTSSIGSYVISALCKDSSGLTSEVRSFTIRIEKPECGNGGIKGGDGKCVCIGNWDTIYQCFECKDGFYGDKCTVLPPCKNGVPNGGVNGDGKCLCNNGWTGSDCSVSNSQSCGSMTSSILSSSNAVSSYLNPIKAQVYLANDKKFDFPLVLSIPSTLSKLDVYLLVDANMNSAATFLNIYNGMDNFISSVKKFAEDTQFGLGIFSDYPSNSITFQPNSNIGSDISSAIREFKPSSYSSSSNGNSLLAATQASSAQVGWNSGSFKVIVIITDIDYQANPTEKSSFTNSLIDKSVVPVVIGFGSPIPNWGASISSNGFGYTVQSAITSGDWSTKAAAGIKAVSSKLVYKSGEMANGKSLVTSLPIGETITQSTQKTVTISLLKPATTNIESPVAKVSVMGYGQTVISINSNRQPTVSNSGFSVDQNSFATFKLTGSDADLNILTFKFTSFLDSTAGIITSSSGVDVSTQTNTFYSSTEVFKFTPKKNYIATSSISFIANDGCVDSTAATITITINRINQAPECQPITINALLNQQVGISLSASDFEDVASKIAIFVSNPSPLTVYGSFNYQDKPITTTTTINNPWQLTFKQIVNPPSAISVGVPFKSRDSASLYSKECLITVNFVHTNEAPISSSLSPVPVNPRDKTTITLTSTDYDSTSATFNIKSFTTGTDGKGTFYICPQLGDCSCTTTQIKLQKNYVSSAVSYSTNIANLGICFSNDQSSQITDYASVTFTSTDNQGLESLPVTVNINVVGTRPNSPPTIISIPKYSVFQDYKDYDKSSKIIDGTDTDQDDYDKSQGVNNLIAVITEKPKKGTLYLKNDGSVASNSPAPMEIYYVPNPGTFGDDTYSYKVIDTLQASSTIATTTVSVIQINHKPSVSADSYSFTSQDVQFEKSLVTSDFDGDQVNCQVIALPNQISMYDSEGILITQVPAKLSKNSYSFRLLDPSLIIPSPFSNVQSQFTVNCLDVTSKTDPFGPLQSDDLIVNVGYIYINTPPKTKTLTVQLDQDTSKAFTFNGDDIETPTSDLKVKIFSLPTNGRLSNQYGYLNGTSISSRTYYLNELTYTPNAGLSNWDTEDNNSPLDKISYAVLDKGGLSSETDLVYFSVRPRNPPIYTGKDEINVLQNTRYPLTIIGEIGNGGSSVAISVVSFTGNGTLYETFNMGSEGTIDRQISSYPVNRSDSLVGSYFYAYKPPHNQYGDDFDTITFVLIDGDLVSKIYTVTVNVIHVNQPPTIKLISYKVLGGSGKEIEFGSNSTVNMNINTMALVKYIGNDIDKDQVGPLGSKVLNIPLTGTIYKFNNETTPLGAIIKDKNLNIERNDDGFYYFVFVPIKGSTGQGYARVPLIVIDDGGLVSPSESVDFNVNNINIPPVITIDKEKRSYSLLTNLTISATKITFDDPDSKNNDVSITISIVGEKDETVVPFSNVSFTVTTGKATCKPDSTLSSITCVGKKSELNKVISKIDIIAKVAGNYRLKVFVDDLGYNSPISIRSSTHLNATDYVTLQISSPEVTTQNSSNKTVLSGAIAGAAAGTALIAAAMWKMLRKAAPPTDAFFDEGAFLGDGVNSNPMYQESKNGGENPLYLASNETL
What is the function of this protein?
Implicated in cellular adhesion.
What are the official names of this protein?
Integrin beta-like protein B.
What is the protein family that this protein belongs to?
Belongs to the SIB family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: CLPX_CLOAB
Sequence: MAKYDNKKQLRCSFCGKSQDQVKRLIAGPGVYICDECIELCSEIIADEFEETPQINVGSLPKPSEIKDYLDQYVVGQEDAKKSLSVAVYNHYKRINSNLSNNDDIELQKSNILLLGPTGCGKTFLAQTLAKFLNVPFAIADATTLTEAGYVGEDVENILLKLIQNADYDVERAEKGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQINTTNILFICGGAFDGVDKIIENRTRVSTIGFGASIQSKQQKDIGAILKKIMPGDLLKFGLIPEFIGRLPIIVTLNSLDQGALVKVLSEPKNALVKQYEKLLQMDNVELEFKDGALKAIASEAISRSTGARGLRAIVEDIMKDIMFDIPSREDVKKVIVTENTINTKQPELVLEEGAKAIEAPKKKEKSKTKKDIESA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: INV_KLULA
Sequence: MLKLLSLMVPLASAAVIHRRDANISAIASEWNSTSNSSSSLSLNRPAVHYSPEEGWMNDPNGLWYDAKEEDWHIYYQYYPDAPHWGLPLTWGHAVSKDLTVWDEQGVAFGPEFETAGAFSGSMVIDYNNTSGFFNSSTDPRQRVVAIWTLDYSGSETQQLSYSHDGGYTFTEYSDNPVLDIDSDAFRDPKVFWYQGEDSESEGNWVMTVAEADRFSVLIYSSPDLKNWTLESNFSREGYLGYNYECPGLVKVPYVKNTTYASAPGSNITSSGPLHPNSTVSFSNSSSIAWNASSVPLNITLSNSTLVDETSQLEEVGYAWVMIVSFNPGSILGGSGTEYFIGDFNGTHFEPLDKQTRFLDLGKDYYALQTFFNTPNEVDVLGIAWASNWQYANQVPTDPWRSSMSLVRNFTITEYNINSNTTALVLNSQPVLDFTSLRKNGTSYTLENLTLNSSSHEVLEFEDPTGVFEFSLEYSVNFTGIHNWVFTDLSLYFQGDKDSDEYLRLGYEANSKQFFLDRGHSNIPFVQENPFFTQRLSVSNPPSSNSSTFDVYGIVDRNIIELYFNNGTVTSTNTFFFSTGNNIGSIIVKSGVDDVYEIESLKVNQFYVD
What are the official names of this protein?
Invertase, Beta-fructofuranosidase, Saccharase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 32 family.
Protein: LDH_MYCCT
Sequence: MKKTANKVVLIGAGAVGTSFLYAAINQGIAEHYVLIDAFPQPAEGNALDLSDTLAVIPHSFTSIKAGSYEDCKDADVVVITAGRPQKPGETRLEMVAGNAEIMKNIATEVKKSGFDGITVIASNPVDVITHVYQKVTGFDPHKVIGSGTTLDSARLRRLVGQKLNVKPESVQAYVAGEHGDSSVAIWSQANIMGRPILDYVKCGCLTLEDLDQIQKDTVDMAYKIINLKRATFYGIGACLTKIVNAVLRDEKATLMVGAQLNGEYKNKDLYTGVPAIIGSNGWEKIIEWDLTKEEQEKFDKSCETLHKTIDSVKHLF
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PALY_POPTR
Sequence: METVTKNGYQNGSLESLCVNQRDPLSWGVAAEAMKGSHLDEVKRMVADYRKPVVKLGGETLTIAQVASIAGHDTGDVKVELSESARPGVKASSDWVMDSMDKGTDSYGVTTGFGATSHRRTKQGGALQKELIRFLNAGIFGNGTETCHTLPHSATRAAMLVRINTLLQGYSGIRFEILEAITRLLNNNITPCLPLRGTITASGDLVPLSYIAGLLTGRPNSKATGPTGEVLDAAEAFKAAGIESGFFELQPKEGLALVNGTAVGSGLASMVLFETNVLAVLSELLSAIFAEVMNGKPEFTDHLTHKLKHHPGQIEAAAIMEHILDGSAYMKAAKKLHETDPLQKPKQDRYALRTSPQWLGPQIEVIRFSTKSIEREINSVNDNPLIDVSRNKAIHGGNFQGTPIGVSMDNVRLAIASIGKLLFAQFSELVNDFYNNGLPSNLTASRNPSLDYGFKGAEIAMASYCSELQYLANPVTTHVQSAEQHNQDVNSLGLISSRKTAEAVDILKLMSTTFLVALCQAIDLRHLEENLKSAVKNTVSQVSKRVLTTGANGELHPSRFCEKELLKVVDREYVFAYVDDPCSATYPLMQKLRQVFVDHALENGENEKNFSTSVFQKIEAFEEELKALLPKEVESARAAYDSGNSAIDNKIKECRSYPLYKFVREELGTVLLTGEKVQSPGEEFDKVFTAMCQGKIIDPMLECLGEWNGSPLPIC
What is the function of this protein?
This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton.
What are the official names of this protein?
Phenylalanine ammonia-lyase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAK_MYCAV
Sequence: ARAVGIDLGTTNAVVAVLEG
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: ARAA_ECO81
Sequence: MTIFDNYEVWFVIGSQHLYGPETLRQVTQHAEHVVNALNTEAKLPCKLVLKPLGTTPDEITAICRDANYDDRCAGLVVWLHTFSPAKMWINGLTMLNKPLLQFHTQFNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHAVVTGHWQDKQAHERIGSWMRQAVSKQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVVNSISDGDVNALVDEYESCYTMTPATQIHGEKRQNVLEAARIELGMKRFLEQGGFHAFTTTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMEDYTYHFEKGNDLVLGSHMLEVCPSIAVEEKPILDVQHLGIGGKDDPARLIFNTQTGPAIVASLIDLGDRYRLLVNCIDTVKTPHSLPKLPVANALWKAQPDLPTASEAWILAGGAHHTVFSHALNLNDMRQFAEMHDIEITVIDNDTRLPAFKDALRWNEVYYGFRR
What is the function of this protein?
Catalyzes the conversion of L-arabinose to L-ribulose.
What are the official names of this protein?
L-arabinose isomerase.
What is the protein family that this protein belongs to?
Belongs to the arabinose isomerase family.
Protein: Y2442_PSEPK
Sequence: MSEHETAGEGRFNSIEIRVLGSLIEKQATSPESYPLTLNALVLACNQKTSREPVMNLTQGQVGQALRALEGQGMTRLQMGSRADRWEHRVDKALELVPAQLVLMGLMFLRGPQTLNELLTRSNRLHDFDDTEQIQHQLERLISRDLALHLPRQAGQREDRYTHALGDPAEIEAILAARQQEGGARTSGGSVSEDRIEALEARIAALEARLAELEG
What are the official names of this protein?
UPF0502 protein PP_2442.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: PANC_RHOPB
Sequence: MSRSPVIVRTLPALRRALDTLRARNASLALVPTMGALHDGHVSLVRLAKRRASKVAVSIFINPAQFAPNEDFAAYPRTWKADLARLTAEKVDLIWNPDAKTMYPAGFASKILTEGPALAGLEDRFRPQFFGGVTTVVGKLFAQVRPDLALFGEKDFQQLRVVARMARDLDLGVKVVGAQIVRERDGLAMSSRNRYLSPEHRESATALCRGLKEAAKRIRAGEAIEAALAGSAALITAAGFKIDYLEARHAETLAPVASRKDGPIRLLVAATIGTTRLIDNVAV
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIBB_ECO8A
Sequence: MNQTLLSSFGTPFERVENALAALREGRGVMVLDDEDRENEGDMIFPAETMTVEQMALTIRHGSGIVCLCITEDRRKQLDLPMMVENNTSAYGTGFTVTIEAAEGVTTGVSAADRITTVRAAIADGAKPSDLNRPGHVFPLRAQAGGVLTRGGHTEATIDLMTLAGFKPAGVLCELTNDDGTMARAPECIEFANKHNMALVTIEDLVAYRQAHERKAS
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: PSBH_ARATH
Sequence: MATQTVEDSSRSGPRSTTVGKLLKPLNSEYGKVAPGWGTTPLMGVAMALFAVFLSIILEIYNSSVLLDGISVN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein H, PSII-H, Photosystem II 10 kDa phosphoprotein.
What is the protein family that this protein belongs to?
Belongs to the PsbH family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: LYSY_PYRIL
Sequence: MKKVCIVGASGFTGGELLRILLQHRGVEIVCATSRRFKGEYVYRVHPNLRGFTQLKFVEPSIDVALKADVVFLALPHGESVKWVPKLYESGVAVFDLSADFRLKDPNAYVEWYKWPQPHPYPDLLQKAVYGQPELHRDELVGAKLVAVPGCMATASILMLAPLAKFGLLSDTPPVVDAKIGSSGAGAEGSVVDLHSFRTYVVRPYEPVHHRHIAEIEQELTRLAGRKVRIAFTPHAVDIVRGIFTTGHVYVEKLPSETDMWRYYRALYGDSKFIRIVKDRLGISRYPNVKYVLGTNIVDLGFELDPRLNRVVTFAAIDNLVRGAAGQAVQAFNIAMGFPEDEGLRQIPIAPL
What is the function of this protein?
Involved in both the arginine and lysine biosynthetic pathways.
What are the official names of this protein?
Putative [LysW]-L-2-aminoadipate/[LysW]-L-glutamate phosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_AERHH
Sequence: MEKPVVLGTLGTVYGIKGWLKVNSFTDVAEAIFDYNPWLINQNGVWREIQVSSWKRHNKGLICKLDGIDVREDALALTNVEIGVAADLLPALPEGEFYWRDLIGCSVVTTKGYDLGKVTELMETGSNDVLVVEANVKDAFGAKERLIPFLEEQVIKNIDLTARTIEVDWDPGF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REV_HV1BN
Sequence: ELLKTVRVIKFLYQSNPPPRPEGTRQARRNRRRRWRARQRQIQSLSGWILSTFLGRSAEPVPLQLPPLERLTLDCNEDCGTSGTQGVGSPQILVESPTVLESGTKE
What is the function of this protein?
Escorts unspliced or incompletely spliced viral pre-mRNAs (late transcripts) out of the nucleus of infected cells.  These pre-mRNAs carry a recognition sequence called Rev responsive element (RRE) located in the env gene, that is not present in fully spliced viral mRNAs (early transcripts).  This function is essential since most viral proteins are translated from unspliced or partially spliced pre-mRNAs which cannot exit the nucleus by the pathway used by fully processed cellular mRNAs.  Rev itself is translated from a fully spliced mRNA that readily exits the nucleus.  Rev's nuclear localization signal (NLS) binds directly to KPNB1/Importin beta-1 without previous binding to KPNA1/Importin alpha-1.  KPNB1 binds to the GDP bound form of RAN (Ran-GDP) and targets Rev to the nucleus.  In the nucleus, the conversion from Ran-GDP to Ran-GTP dissociates Rev from KPNB1 and allows Rev's binding to the RRE in viral pre-mRNAs.  Rev multimerization on the RRE via cooperative assembly exposes its nuclear export signal (NES) to the surface.  Rev can then form a complex with XPO1/CRM1 and Ran-GTP, leading to nuclear export of the complex.  Conversion from Ran-GTP to Ran-GDP mediates dissociation of the Rev/RRE/XPO1/RAN complex, so that Rev can return to the nucleus for a subsequent round of export.  Beside KPNB1, also seems to interact with TNPO1/Transportin-1, RANBP5/IPO5 and IPO7/RANBP7 for nuclear import.  The nucleoporin-like HRB/RIP is an essential cofactor that probably indirectly interacts with Rev to release HIV RNAs from the perinuclear region to the cytoplasm.
What are the official names of this protein?
Protein Rev, ART/TRS, Anti-repression transactivator, Regulator of expression of viral proteins.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 REV protein family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Note=The presence of both nuclear import and nuclear export signals leads to continuous shuttling between the nucleus and cytoplasm.
Protein: PROB_BURP6
Sequence: MRSIIADSKRLVVKVGSSLVTNDGRGLDHDAIGRWAAQIAALRGAGKEVVLVSSGAIAEGMQRLGWSKRPREIDELQAAAAVGQMGLAQVYESRFAEHGIRTAQILLTHADLADRERYLNARSTLLTLLRLGVVPIINENDTVVTDEIKFGDNDTLGALVANLIEGDTLVILTDQPGLFTADPRKDPGATLVAEASAGAPELEAMAGGAGSSIGRGGMLTKILAAKRAAHSGANTVIASGRERDVLVRLAAGEAIGTQLIARTARMAARKQWMADHLQVRGHVVIDAGAVDKLTAGGKSLLPIGVVAVQGVFARGEVIACVDDTGREVARGITNYSSAETKLIQRKPSGEIETVLGYMLEPELIHRDNLVLV
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.