PharMolix/UniProtQA huggingface dataset:
Protein: TRI42_HUMAN
Sequence: METAMCVCCPCCTWQRCCPQLCSCLCCKFIFTSERNCTCFPCPYKDERNCQFCHCTCSESPNCHWCCCSWANDPNCKCCCTASSNLNCYYYESRCCRNTIITFHKGRLRSIHTSSKTALRTGSSDTQVDEVKSIPANSHLVNHLNCPMCSRLRLHSFMLPCNHSLCEKCLRQLQKHAEVTENFFILICPVCDRSHCMPYSNKMQLPENYLHGRLTKRYMQEHGYLKWRFDRSSGPILCQVCRNKRIAYKRCITCRLNLCNDCLKAFHSDVAMQDHVFVDTSAEEQDEKICIHHPSSRIIEYCRNDNKLLCTFCKFSFHNGHDTISLIDACSERAASLFSAIAKFKAVRYEIDNDLMEFNILKNSFKADKEAKRKEIRNGFLKLRSILQEKEKIIMEQIENLEVSRQKEIEKYVYVTTMKVNEMDGLIAYSKEALKETGQVAFLQSAKILVDQIEDGIQTTYRPDPQLRLHSINYVPLDFVELSSAIHELFPTGPKKVRSSGDSLPSPYPVHSETMIARKVTFSTHSLGNQHIYQRSSSMLSFSNTDKKAKVGLEACGRAQSATPAKPTDGLYTYWSAGADSQSVQNSSSFHNWYSFNDGSVKTPGPIVIYQTLVYPRAAKVYWTCPAEDVDSFEMEFYEVITSPPNNVQMELCGQIRDIMQQNLELHNLTPNTEYVFKVRAINDNGPGQWSDICKVVTPDGHGKNRAKWGLLKNIQSALQKHF
What are the official names of this protein?
Tripartite motif-containing protein 42.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
Protein: DCXH_PLAF7
Sequence: MENFDEVIKEYQKYLEGKEKTHKINSCKHPCCEEDNLKSVKNYFKVYHKKYIPSIIQKKKKERNEHAPPLLKDIQDKRCTNVFERLNDKQFYTGVQKTKFMELLKNNKNKSSYCYNNIKVFSTMLKKPCNYVVTPGTLGIQKYGIQTGRPKTIFLFNNEKKYDKGVYFLVKSYIKNIKSLCYEITKILQPSIGPTRKIYDQNFSLVRNVNDLINGGKYLCTSGDPPAPIRNLSLHFLT
What is the function of this protein?
Involved in the stabilization of microtubules (PubMed:33633135).  Probably by controlling microtubules stabilization, plays a role in invasion, microneme secretion and parasite growth in host erythrocytes (PubMed:32493727).
What are the official names of this protein?
Doublecortin domain-containing protein, PfApicortin.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Note=Localizes to the parasite surface in subpellicular regions in trophozoites and schizonts (PubMed:33633135). In merozoites, localizes to the apical end of the parasite (PubMed:33633135).
Protein: SYT_DESVH
Sequence: MNVSIEGQMLEVASGASCGDALKGALSGKKFKNVLACRLDGGLVDITATVPDGTTTIEPVYADSPEGLDLIRHSTAHIMACAVKRLFPAAKVTIGPSIDNGFYYDFDAERPFSPEDFEAIEREMQKIVDAATPFERSEMPRDEAVALFEGMGETYKVEIIRDLPNDTVSLYRCGEFVDLCRGPHIPHAGFAKAFKLMSVAGAYWRGDEKNPMLSRIYGTAFADAKTLKEHLHRIEEAKRRDHRKLGQQLDLFAFHEDVAPGMVFWHPKGMLVRTIIEDFLRKEHLKRRYDIVQGPQLLRRELWEKSGHYDNYRENMYFTEIDENAYGVKPMNCLAHMLIYRSAIRSYRDLPKRFFELGVVHRHEKSGVLHGLLRVRQFTQDDAHIICRPDQLEDEIIDVIALVRDLMNLFGFDYKVAVSTRPEKSIGSDEAWELATNALVKAVERAGIPYTINEGDGAFYGPKIDVRLMDCIGREWQCSTIQCDFTLPERFDLVYVGQDGERHRPVMVHRAILGSLERFIGVLIEQYAGAFPAWLAPVQARLLTVTDAQNEFVESARAALAKAGIRVEADVRNEKLGYKVREAQLEKIPYILVVGDKEVEAGGVNVRLRTGENLGLKSLDEVVSLLESDCQEPFKRGGMSYSFS
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYAY_ECOUT
Sequence: MNDSEFHRLADQLWLTIEEHLDDWDGDSDIDCEINGGVLTITFENGSKIIINRQEPLHQVWLATKQGGYHFDLKGDEWICDRSGETFWDLLEQAATQQAGETVSFR
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: MTNB_LEPBA
Sequence: MDLITSLQEITKLSHLYYERQWMYATAGNLSTRDGSSRDQFWITASGKHKGELKDTDFVCVSVADGTLLKASDGLKPSAETSIHQVLYSQMPDIGCCLHVHTIDSNLLEFGVGKEEGSREIPIPPIEIIKAFGIWDEKPNLTMPVFYNHTHVPTIADEIKRYFISVGIPKVPFLLIEGHGPTVWGKSIAEANKHLEAVHFLLQVMARKV
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
What are the official names of this protein?
Methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
Protein: SAT_SYNFM
Sequence: MSKLVPPHGKEKKLKPLLLEGAALAAEKEKAKTLKVVPMTSREASDLIMLGIGAFTPLDGFMGYADWKGVCDKYTMADGVFWPIPITLSADKAVADSIGKNEEVALLDVENNEILGTMKVTEKYTIDKEHECKSVFWTNDAAGHPGVAKVMAQKEVNLAGPVKVISESFYPTQFKNVYQRPAEARKLFDEKGWRRVAALQLRNPMHRSHEFLAKIAVEVMDGLYIHQLVGKLKEGDIPADVRVKAIDVLVENYFVKDTVIQGGYPAEMRYAGPREALLHAVFRQNYGCSHLIVGRDHAGVGDYYGPFDAQKIFDDIPEGALLLQPLKIDWTFHCFKCGGMASMRTCPHGKADRLLLSGTMVRKTLSEGGELPKEFSRPEVVKVLQEYYAGLEEKVEIKLHGAATGDVKKK
What are the official names of this protein?
Sulfate adenylyltransferase, ATP-sulfurylase, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the sulfate adenylyltransferase family.
Protein: GATB_ARATH
Sequence: MSTTLLRTIQLNQFSLLGTSLLRRRRSNNFSVRSCGSQTTTTHEAKQSSPTRVAPKNHKSNQLDEILRDYEAVIGIETHVQLSTLTKAFCSCSNNYGSYPNTSICPVCMGLPGALPVLNSKVVEFGVRLGLALNCDLSLKSKFDRKQYFYPDLPKGYQISQFDIPIASGGYVDVDIPLEFGGGHRRFGITRVHMEEDAGKLLHSDTGDYSQVDLNRAGVPLLEIVSEPDMRSGIEAAEYACEMQRIARYLGVSNGNMQEGSLRCDVNISIRPIGQAEFGTKVEIKNLNAFSAISRAIDFEISRQALLYNQGKADQIVTETRLWEEGAQKTVTMRKKEGLADYRYFPEPDLPEVILTQEYVDSIRASLPELPEAKRRRYEAMGLGMQDVLFLANDVSVAEYFDAVIGKGAEVKLAANWIMSDIAAYLKNEKLSINDIKLTPQELAELIAAIKDGTISGKIGKEILFELLAKGGTVKGMIKAKDLVQITDPAEIEKMVIQVVSENPKQLEQYRSGKTKLQGYFAGQVMKMSKGKANPGLLNKILLEKLNAKD
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in chloroplasts and mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit B, chloroplastic/mitochondrial, Glu-AdT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
What are the subcellular locations of this protein?
Mitochondrion. Plastid, chloroplast.
Protein: 3HAO_USTMA
Sequence: MPFPLPLNFPKWLSENEHLLQPPVGNFCLFRTRDYTVMAVGGPNARSDYHYQPTEEFFYQYKGDMLLKVIDEDGKFQDIPIKQGEMFMLPAHTPHSPVRFANTVGIVVERTRPDGSPDAMRWYCPNKEAHGETPTLVKEVHFQCTDLGTQLKPIIDAWVNDEAGRQCSHCGYTQGARELPA
What is the function of this protein?
Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
What are the official names of this protein?
3-hydroxyanthranilate 3,4-dioxygenase, 3-hydroxyanthranilate oxygenase, 3-HAO, 3-hydroxyanthranilic acid dioxygenase, HAD, Biosynthesis of nicotinic acid protein 1.
What is the protein family that this protein belongs to?
Belongs to the 3-HAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRQ_YERE8
Sequence: MRLTLRQIKWLKVAIWLAAALPFLWLILSVDQGWFSADPAKDIQHFTGRMTLKLLLATLLVTPLARYGKQPLLIRCRRLLGLWCFAWGTLHLVSYSVLELGLSNIGLLGRELVTRPYLTLGIISWLLLLSLAVTSTLWAQRKMGANWQKLHNLVYVVAILAPIHYLWSVKTLSPLPIIYAVTAAILLALRYKKFRQWCR
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation.  MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ, Flavocytochrome MsrQ.
What is the protein family that this protein belongs to?
Belongs to the MsrQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: STX8B_DICDI
Sequence: MGDYWLNEHDNIVKLINSLTADIKEYSIQQRNNPGIVQKNTPAKLRNGLVHITNEILRLQDSLTYGNNRNIQEKELLRRKNKVESLISMKNQLNSTLDAAINNTSQKNELMGNNNGVGIGYSNRQFGKPKETEATKQFDNQQLFTNQQHIMREQDESLDLLSQSIMRQKNMAHAMSNELDQHNEMLDDVEIGTDAVSMRLRNANRRMETIKQNAGSTCMIVCIVILIILIVVLIATDSGCKIYNDPKHCP
What are the official names of this protein?
Probable syntaxin-8B.
What is the protein family that this protein belongs to?
Belongs to the syntaxin family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: T23O_ARTS2
Sequence: MSVEKNTRQLEKDIVRDFSSRMSYASYLQLPTLLSAQQPVSNPEHHDEMLFIIQHQTTELWLKLVLHELRSAAAWLRSDDLGSALKAIARVKHIQKTLTEQWSVLATLTPTEYSQFRRFLGNSSGFQSSQYRAVEFVLGNKNRKMLPVFESDPEAYQQLSNVLEAPSIYDEFLAYLNRQGFDIPTSLLERDVTKAHQFCPELVPVFKHIYENAADNWGAYEACEELVDLEDNFQLWRFRHLRTVQRTIGMKAGTGGSSGAAFLQKALELTFFPELFAVRTEIGQ
What is the function of this protein?
Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine.  Catalyzes the oxidative cleavage of the indole moiety.
What are the official names of this protein?
Tryptophan 2,3-dioxygenase, TDO, Tryptamin 2,3-dioxygenase, Tryptophan oxygenase, TO, TRPO, Tryptophan pyrrolase, Tryptophanase.
What is the protein family that this protein belongs to?
Belongs to the tryptophan 2,3-dioxygenase family.
Protein: MENC_SYNY3
Sequence: MDKPYHVKFYSYNFPLPKPVVTAHGHWQRRRGLIVELTDQRGNRGRGEIAPLPWFGTEDLASATDFCRSLKGRITPAQIEKIGDRLPCCGFAFGSAEWELESGSVIENSPNSLSYCQLLPTGEAALDYLASNPQLGASTFKWKIGVGDFAVERDLYGQLWRRLPEGCQIRLDANGGLSVDIAQQWLTLLDRQRENSGPKIQYLEQPLPPGEIDEMFRLQEDFATSIALDEAVCSLAQLAQLYDKGWSGLYILKAAIMGNPRVLNHWLKTHPIPAIFSSVFETAIARGQVLALAQKWNLPDHAVGFAPLREPITEATPDSV
What is the function of this protein?
Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
What are the official names of this protein?
o-succinylbenzoate synthase, OSB synthase, OSBS, 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase, o-succinylbenzoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
Protein: GMH3_SCHPO
Sequence: MAVLQWKLSRVIFVLLIIGISSFLIYFQFGNSFSASPALERLQDVFSKPSVQEYDYLVPLDEDMQGLSTTYHQATINEDDPQEPKSHEIVILLASDGRSSGNMAPETFNQCIENRINYAKHHNYGFEYVNVSQMNIPPVWAKMPAIIQTMNKHPHAKWIWWLDQDALILNTELSIQEHILSPDVLVEKLMKNEPMISPFSADLERLTPSSYTVDSARSLGLLISQDLNGLNAGSFFVRRSPMMALFLDLWGDKSFRENKVADHEQALLGYFVRYHPEIAAIIGILPQTLINSYPVGQPEMGWKEGHLVIHFAGCWVENRCQVLWDEYRERVH
What is the function of this protein?
Involved in the galactosylation of the N-linked core oligosaccharide Man(9)GlcNAc(2).
What are the official names of this protein?
Alpha-1,2-galactosyltransferase gmh3.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 34 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: CYB_PERGU
Sequence: MTNLRKTHPLMKIINDAFIDLPTPSNISAWWNFGSLLGVCLVIQILTGLFLAMHYTSDTLTAFSSVAHICRDVNYGWLIRNLHANGASIFFICLFLHVGRGIYYGSYLFKETWNIGVILLLTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIVTAMVIVHLLFLHETGSNNPSGLNPDADKIPFHPYYTIKDALGLLLMILLLLLLAMFSPDMLGDPDNFSPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLMSILILLVIPFLHTSKQRSLMFRPISQTLFWLLTADLFTLTWIGGQPVEQPFIIIGQVASILYFLIIIALMPLAGLLENYMLKPKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: OGG1_THEMA
Sequence: MEELLKELERIREEAKPLVEQRFEEFKRLGEEGTEEDLFCELSFCVLTANWSAEGGIRAQKEIGKGFVHLPLEELAEKLREVGHRYPQKRAEFIVENRKLLGKLKNLVKGDPFQSREFLVRNAKGIGWKEASHFLRNTGVEDLAILDKHVLRLMKRHGLIQEIPKGWSKKRYLYVEEILRKVAEAFGESPGKFDLYLWYLVKGKVDK
What is the function of this protein?
Catalyzes the excision of an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 8-oxoG) from DNA.  Also cleaves the DNA backbone at apurinic/apyrimidinic sites (AP sites).
What are the official names of this protein?
8-oxoguanine DNA glycosylase/AP lyase.
What is the protein family that this protein belongs to?
Belongs to the type-2 OGG1 family.
Protein: THYX_HALMA
Sequence: MDVKLLEATDDPEDLICKAARNDYSDTSVGSQSFEATMAEVDGDSLEEKKETLIGHLLDHGHFGPFEHAQATFAVEGVSRSCMAQITRHRHVSFDVQSMRYVSFDDVDPEAVREGELVVTPPSATDPDWIGRNQQKASVSDEEFEERAEIFKDTIEQAVESYQELLELGMPPEDARFVLPIGTKVNIVMSMNARMLMHVADMRAAADAQWEIREMTEEMLELAADWCPKTFEYYEQEMKGRKNRLAP
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
What are the official names of this protein?
Flavin-dependent thymidylate synthase, FDTS, FAD-dependent thymidylate synthase, Thymidylate synthase ThyX, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase ThyX family.
Protein: DDRGK_MONBE
Sequence: MWGPLIYALLGLAIVAAAFLFVRRSQAKEVVPVADDDDKENGAAADEVNPRQAGDQGHTDDEDGEEGNEGLKNFMYDENGKKLGVKKARKLQEKEERRRRNEEMAQAREQAKLLQHQEEEERKEREAEEAEDERQREAELEREREAQRQKELEEYNSLKSMFVVEESGELDVDHEAQAQSLLNEFVSFIKEKKVVQLEDLAAHFGLKTQDTIERIQQLEAEGRLTGLTDDRGKYIFISEEELSEVVKFIERRGRITIAELMDNSNRLISLSETDVEFPGDEPAPADVDETTTA
What are the official names of this protein?
DDRGK domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the DDRGK1 family.
Protein: HPAC_KLEOX
Sequence: MQLDEQRLRFRDAMASLSPAVNVITTEAEAGAAVSPHRPSCSVTDTPPSVMVCINANSAMNPVFQGNGKLCINVLNHEQEEMARHFAGMTGMTMDDRFGLSGWQKGALGQPVLKGALASLEGEISQVQTIGSHLVYLVEIRNITLSQQGHGLIYFKRRFHPVMMEMDVVA
What is the function of this protein?
Catalyzes the reduction of free flavins (FMN, FAD and riboflavin) by NADH.  Subsequently, the reduced flavins diffuse to the large HpaB component or to other electron acceptors such as cytochrome c and Fe(3+) ion (By similarity).
What are the official names of this protein?
4-hydroxyphenylacetate 3-monooxygenase reductase component, 4-HPA 3-monooxygenase small component, Flavin:NADH reductase.
What is the protein family that this protein belongs to?
Belongs to the non-flavoprotein flavin reductase family. HpaC subfamily.
Protein: CARD_MYCTO
Sequence: MIFKVGDTVVYPHHGAALVEAIETRTIKGEQKEYLVLKVAQGDLTVRVPAENAEYVGVRDVVGQEGLDKVFQVLRAPHTEEPTNWSRRYKANLEKLASGDVNKVAEVVRDLWRRDQERGLSAGEKRMLAKARQILVGELALAESTDDAKAETILDEVLAAAS
What is the function of this protein?
Controls rRNA transcription by binding to the RNA polymerase (RNAP).  Required for replication and persistence during infection of mice (By similarity).
What are the official names of this protein?
RNA polymerase-binding transcription factor CarD.
What is the protein family that this protein belongs to?
Belongs to the CarD family.
Protein: NU3C_MANES
Sequence: MFLIYEYDIFWAFLIISSVIPILAFLISGVLSPISKGPEKLSSYESGIEPIGDAWLQFRIRYYMFALVFVVFDVETVFLYPWAMSFDVLGLSVFIEALIFVLILIVGSVYAWRKGALEWS
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic, NAD(P)H dehydrogenase subunit 3, NADH-plastoquinone oxidoreductase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: TRPA_CYAP4
Sequence: MVSVSTCFSALRDRAQCALIPFITAGDPSLEITAKALQVLDQQGADLIELGVPYSDPLADGPTIQAAATRALQKGTRLDAVLEMISHVAPNLRSPLILFTYYNPIFHRGVEPFLQQVAQAGVQGLVVPDLPLEEADTVLTQAAAVGIELTLLVAPTTPRSRIAAIAERSQGFIYLVSTTGVTGMRSKVEGRVHELLLELQQVTDKPIGVGFGISQPEHARQVMEWGADAAIVGSAFVKRLAEGTPEQGLAAIADFCRSLKTALTPVD
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: TM247_MOUSE
Sequence: MAMEDREVMEARGAGESCPTLSKVAPVDSMPEGKPKASLDAEVPKLELPTLEENGICEDRDCPGPPRSLPPKSGPNAKGQAGDGPGLESVELPLPLETEHRNAMELEKVRMEFELTLLKYLHQENERQRQHEEVMEQLQQQQQQQQALPHQFSGSLQDLLLPQNQFAMFFYCFIFIHIIYVAKETVFFLFSKHYLFCLAAILLCLIKTLWS
What are the official names of this protein?
Transmembrane protein 247.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NAGB_STAA9
Sequence: MKVLNLGSKKQASFYVACELYKEMAFNQHCKLGLATGGTMTDLYEQLVKLLNKNQLNVDNVSTFNLDEYVGLTASHPQSYHYYMDDMLFKQYPYFNRKNIHIPNGDADDMNAEASKYNDVLEQQGQRDIQILGIGENGHIGFNEPGTPFDSVTHIVDLTESTIKANSRYFKNEDDVPKQAISMGLANILQAKRIILLAFGEKKRAAITHLLNQEISVDVPATLLHKHPNVEIYLDDEACPKNVAKIHVDEMD
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: MRAY_SHIBS
Sequence: MLVWLAEHLVKYYSGFNVFSYLTFRAIVSLLTALFISLWMGPRMIAHLQKLSFGQVVRNDGPESHFSKRGTPTMGGIMILTAIVISVLLWAYPSNPYVWCVLVVLVGYGVIGFVDDYRKVVRKDTKGLIARWKYFWMSVIALGVAFALYLAGKDTPATQLVVPFFKDVMPQLGLFYILLAYFVIVGTGNAVNLTDGLDGLAIMPTVFVAGGFALVAWATGNMNFASYLHIPYLRHAGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGIIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISLMLVLIGLATLKVR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PPAL_YEAST
Sequence: MTIEKPKISVAFICLGNFCRSPMAEAIFKHEVEKANLENRFNKIDSFGTSNYHVGESPDHRTVSICKQHGVKINHKGKQIKTKHFDEYDYIIGMDESNINNLKKIQPEGSKAKVCLFGDWNTNDGTVQTIIEDPWYGDIQDFEYNFKQITYFSKQFLKKEL
What is the function of this protein?
Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates.
What are the official names of this protein?
Low molecular weight phosphotyrosine protein phosphatase, PTPase, Low molecular weight cytosolic acid phosphatase.
What is the protein family that this protein belongs to?
Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_LEUCK
Sequence: MRLLGLDVGSRTVGVAVSDPMGWTAQGVEIIRINEDEKEFGLARLGEIIKEKQAKGVVVGLPKNMNNSEGPRAEAARQYAQMVEDQFNLPTDFQDERLTTVQAERMLVEEADVSRKKRKQVIDKIAAEFILQNYLDANGPLTK
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_THET8
Sequence: MVSTLKRDEALFELIALEEKRQREGLELIASENFVSKQVREAVGSVLTNKYAEGYPGARYYGGCEVIDRVESLAIERAKALFGAAWANVQPHSGSQANMAVYMALMEPGDTLMGMDLAAGGHLTHGSRVNFSGKLYKVVSYGVRPDTELIDLEEVRRLALEHRPKVIVAGASAYPRFWDFKAFREIADEVGAYLVVDMAHFAGLVAAGLHPNPLPYAHVVTSTTHKTLRGPRGGLILSNDPELGKRIDKLIFPGIQGGPLEHVIAGKAVAFFEALQPEFKEYSRLVVENAKRLAEELARRGYRIVTGGTDNHLFLVDLRPKGLTGKEAEERLDAVGITVNKNAIPFDPKPPRVTSGIRIGTPAITTRGFTPEEMPLVAELIDRALLEGPSEALREEVRRLALAHPMP
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVD_YERPN
Sequence: MPKYRSHTTTHGRNMAGARALWRATGMTDDDFGKPIIAVVNSFTQFVPGHVHLRDLGKLVAEQIVASGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDKIIKLDLIDAMIQGANPNVSDEESAQIERSACPTCGSCSGMFTANSMNCLNEALGLALPGNGSLLATHADRKQLFLDAGKHIVALTKRYYEQDDVSALPRNIANKAAFENAMILDIAMGGSTNTVLHLLAAAQEGEIDFSMTDIDHLSRKVPHLCKVAPSTQKYHMEDVHRAGGVIGILGELDRAGLLNRDVSNVLGLNLTQTLEAYDVMLTQDEGVKQMYAAGPAGIRTTKAFSQDCRYPSLDTDREEGCIRTREHAYSQDGGLAVLYGNIAADGCIVKTAGVDKDSLTFRGPAKVFESQDEAVEAILGGKVVAGDVVVIRYEGPKGGPGMQEMLYPTTYLKSMGLGKSCALLTDGRFSGGTSGLSIGHVSPEAASGGLIGLVQDGDFINIDIPNRGIVLDVSEAELAARRETEEAHGDAAWSPKGRERQVSYALRAYAMLATSADKGAVRDKSKLGG
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: Y088_MYCTU
Sequence: MSVYKHAPSRVRLRQTRSTVVKGRSGSLSWRRVRTGDLGLAVWGGREEYRAVKPGTPGIQPKGDMMTVTVVDAGPGRVSRSVEVAAPAAELFAIVADPRRHRELDGSGTVRGNIKVPAKLVVGSKFSTKMKLFGLPYRITSRVTALKPNELVEWSHPLGHRWRWEFESLSPTLTRVTETFDYHAAGAIKNGLKFYEMTGFAKSNAAGIEATLAKLSDQYARGRA
What are the official names of this protein?
Uncharacterized protein Rv0088.
Protein: Y929_BURP0
Sequence: MDARLLEILVCPICKGPLHYDRGAQELVCHADKLAYPIRDGIPVMLVDEARQTVEGTPVDPAGPARGR
What are the official names of this protein?
UPF0434 protein BURPS1106A_0929.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.