PharMolix/UniProtQA huggingface dataset:
Protein: AT1_ACTCC
Sequence: MASFPPSLVFTVRRKEPTLVLPSKPTPRELKQLSDIDDQEGLRFQVPVIMFYKRKLSMEGEDPVKVIREALAEALAFYYPFAGRLIEGPNRKLMVDCTSEGVLFIEADADIELNQLIGDTIDPGTYLDELLHDVPGSEGILGCPLLLIQVTRFRCGGWAFAIRLNHTMSDTLGLVQFLTTIAEFTRGAEGAPSVPPVWQREFLAARQPPFIPFHHHEYEQVIDTTPDDNKKSMTHKSFFFGPKEIRAIRSHLPLHHRSTSSTFDVLTACLWRCRTCALVLDPKKTVRISCAASGRGKHDLHVPRGYYGNVSAFPATVLRAGMISTSPLEYAMEGVKKAKAKMTGEYLRSVADLMVTKGRPLYTVVGNYIVSDMTRVGLDTIDFGWGKPVYGGPARAFPLISFYGRFKDNKGEDGIVVLICLPEAAMETFQEELKKMIGEHVDGPFDYNPIKVVSKL
What is the function of this protein?
Involved in the biosynthesis of volatile esters which confer kiwifruit flavor (By similarity).  Alcohol acyl transferase that can use a wide range of alcohols as substrate to produce esters (By similarity).
What are the official names of this protein?
Alcohol acyltransferase 1, AcAT1.
What is the protein family that this protein belongs to?
Belongs to the plant acyltransferase family.
Protein: RS14Z_MYCAP
Sequence: MAKSSLKAKQKKHAKFSTRAYTRCELCGRVHAVLRKYKICRICFRELAHQGKIPGMKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: RUVA_PSEA7
Sequence: MIGRLRGTLAEKQPPHLILDVNGVGYEVEVPMTTLYRLPSVGEPVTLHTHLVVREDAHLLYGFAEKRERELFRELIRLNGVGPKLALALMSGLEVDELVRCVQAQDTSTLVKIPGVGKKTAERLLVELKDRFKAWENMPTIAPLVMEPRASATVSSAEADAVSALIALGFKPQEASRAVAAVPGEDLSSEEMIRQALKGMV
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: US14_HCMVM
Sequence: METVSTQRETASSETERTREAASAETTDATFRSLEEGSTISSRYSETASTASEDAVCWLRRTAIVMRVYGLLTLETAFSVLISALVWLGYPSLGYECRDDPSPLLLSCTPVLVLGALELTDHRHPSNGLVFALYVALLSFTTAGLNLCATAPIGVSSLILTWTLFVACNGVAWEHRLSSVWRDALFTSTLLTVMVSVLASTYTWLHKTLLCLYTVFVGCILAVLFQDVRYIATKMPVSHIIRSSLVLYATETLIYHTTLLMLTPVVWSARWDQMFSYLAKLGTYHHYRVDNGTLSVILNSTTATFQSRVA
What are the official names of this protein?
Membrane protein US14.
What is the protein family that this protein belongs to?
Belongs to the cytomegalovirus US12 family.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: ATAT_MACMU
Sequence: MEFPFDVDALFPERITVLDQHLRPPARRPGTTTPARVDLQQQIMTIIDELGKASAKAQNLSAPITSASRMQSNRHVVYILKDSSGRPAGKGAIIGFIKVGYKKLFVLDDREAHNEVEPLCILDFYIHESVQRHGHGRELFQYMLQKERVEPHQLAIDRPSQKLLKFLNKHYNLETTVPQVNNFVIFEGFFAHQHRPPAPSLRATRHSRAAAVDPTPTAPARKLPPKRAEGDIKPYSSSDREFLKVAVEPPWPLNRAPRRATPPAHPPPRSSSLGNSPERGPLRPFVPEQELLRSLRLCPPHPTARLLLAADPGGSPAQRRRTR
What is the function of this protein?
Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules.  Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity.  Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer.  Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules.  Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released.  Required for normal sperm flagellar function.  Promotes directional cell locomotion and chemotaxis, through AP2A2-dependent acetylation of alpha-tubulin at clathrin-coated pits that are concentrated at the leading edge of migrating cells.  May facilitate primary cilium assembly.
What are the official names of this protein?
Alpha-tubulin N-acetyltransferase 1, Alpha-TAT, Alpha-TAT1, TAT, Acetyltransferase mec-17 homolog.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase ATAT1 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane, clathrin-coated pit. Cell junction, focal adhesion. Cell projection, axon. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle.
Protein: PDXB_SALPK
Sequence: MKILVDENMPYARELFSRLGEVKAVPGRPIPVEELNHADALMVRSVTKVNESLLSGTPINFVGTATAGTDHVDEAWLKQAGIGFSAAPGCNAIAVVEYVFSALLMLAERDGFSLRDRTIGIVGVGNVGSRLQTRLEALGIRTLLCDPPRAARGDEGDFRTLDELVQEADVLTFHTPLYKDGPYKTLHLADETLIRRLKPGVILINACRGPVVDNAALLARLNAGQPLSVVLDVWEGEPDLNVALLEAVDIGTSHIAGYTLEGKARGTTQVFEAYSAFIGREQRVALETLLPAPEFDRITLHGPLDQPTLKRLAHLVYDVRRDDAPLRKVAGIPGEFDKLRKNYLERREWSSLYVMCDDETAAALLCKLGFNAVHHPAH
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LRC66_HUMAN
Sequence: MKNLYFRVITIVIGLYFTGIMTNASRKSNILFNSECQWNEYILTNCSFTGKCDIPVDISQTAATVDVSFNFFRVLLQSHTKKEEWKIKHLDLSNNLISKITLSPFAYLHALEVLNLSNNAIHSLSLDLLSPKSSWVKRHRSSFRNRFPLLKVLILQRNKLSDTPKGLWKLKSLQSLDLSFNGILQIGWSDFHNCLQLENLCLKSNKIFKIPPQAFKDLKKLQVIDLSNNALITILPMMIIALEFPHLVVDLADNNWQCDDSVAVFQNFISESWRKKWNVICNRSIGSEEANGGTPQSRISRETRLPPIHLHRMKSLIRSKAERPQGGRHTGISTLGKKAKAGSGLRKKQRRLPRSVRSTRDVQAAGKKEDAPQDLALAVCLSVFITFLVAFSLGAFTRPYVDRLWQKKCQSKSPGLDNAYSNEGFYDDMEAAGHTPHPETHLRQVFPHLSLYENQTPFWVTQPHPHATVIPDRTLGRSRKDPGSSQSPGQCGDNTGAGSGNDGAVYSILQRHPHAGNRELMSAAQDHIHRNDILGEWTYETVAQEEPLSAHSVGVSSVAGTSHAVSGSSRYDSNELDPSLSGEITASLCKMLTHAEAQRTGDSKERGGTEQSLWDSQMEFSKERQVSSSIDLLSIQQPRLSGARAEEALSAHYSEVPYGDPRDTGPSVFPPRWDSGLDVTPANKEPVQKSTPSDTCCELESDCDSDEGSLFTLSSISSESARSKTEEAVPDEESLQDESSGASKDNVTAVDSLEENVTFQTIPGKCKNQEDPFEKPLISAPDSGMYKTHLENASDTDRSEGLSPWPRSPGNSPLGDEFPGMFTYDYDTALQSKAAEWHCSLRDLEFSNVDVLQQTPPCSAEVPSDPDKAAFHERDSDILK
What are the official names of this protein?
Leucine-rich repeat-containing protein 66.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SECB_BURA4
Sequence: MSDVENQPFFNIQRVYLKDMSLEQPNSPAIFLEQDMPSVEVEVDVKAERLAESVFEVVVSGTVTAKVKDKVAFLIEAKQAGIFDIRNIPDEQLDPLVGIACPTILFPYLRSNIADAITRAGFPPIHLAEINFQALYEQRLAQLQQQAGAAGAPNGAPNGTTLN
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRBA1_RANTE
Sequence: MAQINPLPVPLGPWKITVYDQENFQGKRMEFTSSCANIMECGFDNIRSLKVECGGWIGYEHTSFCGQQFVLERGEYPRWDAWSGSNAYHIERLMSFRPICSANHKESKLVIFEKENFIGRQWEMCDDYPSLQAMGWVNNEVGSMKVQCGSWVCYQYPGYRGYQYILESDHHGGEYKHWREWGSHAQTFQIQSIRRIQQ
What is the function of this protein?
Crystallins are the dominant structural components of the vertebrate eye lens.
What are the official names of this protein?
Beta-crystallin A1.
What is the protein family that this protein belongs to?
Belongs to the beta/gamma-crystallin family.
Protein: PP2A_BRANA
Sequence: SIPTDATLDLDEQISQLMQCKPLSEQQVRALCEKAKEILMDESNVQPVKSPVTICGDIHGQFHDLAELFRIGGMCPDTNYLFMGDYVDRGYYSVETVTLLVGLKVRYPQRITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVESEIFCLHGGLSPSIETLDNIRNFDRVQEVPHGGPMCDLLWSDPDDRCGWGISPRGAGYTFGQDISNQFNHSNSLKLISRAHQLVMDGYNWAHEAKGGTIFSAPNYCYRCGNMASILEVDDCRNHTFIQFEPAPRRGEPDVTRRTPDYFL
What are the official names of this protein?
Serine/threonine-protein phosphatase PP2A catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-2A subfamily.
Protein: NRN1_HUMAN
Sequence: MGLKLNGRYISLILAVQIAYLVQAVRAAGKCDAVFKGFSDCLLKLGDSMANYPQGLDDKTNIKTVCTYWEDFHSCTVTALTDCQEGAKDMWDKLRKESKNLNIQGSLFELCGSGNGAAGSLLPAFPVLLVSLSAALATWLSF
What is the function of this protein?
Promotes neurite outgrowth and especially branching of neuritic processes in primary hippocampal and cortical cells.
What are the official names of this protein?
Neuritin.
What is the protein family that this protein belongs to?
Belongs to the neuritin family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor. Synapse.
Protein: RS4_SHEPC
Sequence: MARYLGPKLKLSRREGTDLFLKSGVRAIDSKCKLETAPGQHGARKPRLSEYGTQLREKQKVRRIYGVLEKQFRNYYKDAARLKGNTGENLLQLLETRLDNVVYRMGFGATRAESRQLVSHKSVMVNGRVVNIPSFKVSANDVVSIREKSRTQARIKAALEVAAQREKPTWVEVDSAKMEGAFKRVPERSDLSAEINEQLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: AROC_GEOKA
Sequence: MRYLTAGESHGPQLTAILEGVPAGLELRAEHINKELARRQKGYGRGRRMQIEKDEVKITGGVRHGKTLGSPIALVVENRDFKHWQTIMAVEPIDDEAEVKRKVTRPRPGHADLNGALKYGHRDMRNVLERSSARETTVRVAAGAVAKRILEEVGIRVAGHVIEIGGVRAKKLDYRSLEELQAVTEESPVRCFDPEAGQKMMEAIDWAKKNGDSIGGIVEVIVEGVPAGVGSYVHYDRKLDAKIAAAIVSINAFKGVEFGIGFEAARRPGSEVHDEIIWSPEQGFSRRTNRAGGFEGGVTTGMPIVVRGVMKPIPTLYKPLQSVDIETKEPFAASIERSDSCAVPAASVVAEAVVAWEVAAAIVEQFGQDRMDLIKENVERARRYAKEF
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: Y1724_PYRFU
Sequence: MYPENYEKFEKIIERLREFKGVIIVEGKRDEDSLRKLGVQTEILRLSRSSLADVALLASEHEEVMILTDFDETGEKLAKRLYDLLVGLTKVDMETRRELQFIASKDAKGIEDLYDLWESLRLRFWAPKEGD
What are the official names of this protein?
UPF0292 protein PF1724.
What is the protein family that this protein belongs to?
Belongs to the UPF0292 family.
Protein: MTB1_GEOSE
Sequence: METVQMSLDLQPEDTKANIECSSPDYEIKCFSHNQFAPQIERLKIEKKYIHIVEETETFNRKLVSYQANKNQSIHNWIRYKEGFSSELVQNLIEEFGLSKGDTILDPFLGSGTTSLTAKMLGINSIGIDILPISHIAFEPKSFIFEYNLEELDRAYKEIYEISPTKIEQKFNHLSITEGAFPEETENDLLFFTHWDNNSQYSYQTKTLIKLILVSILEEISYTRKDGQYLRWDYRSQKVIETNKKRLEQGKEPIKTILDKGELPTVKESLLNTLLTIKEDIKEIQQKCLPNESVHELIKDSALNALPKINDNTFDAVITSPPYCNRYDYTRTYALELAYLGVDEKKIRELRQAQLSCTVENKSKLKQLKDYYHSLFLESRYAEIERLVTGNEVLNEINYALRKRWENGEVNNKGILSMVDGYFTELTFIFYELFRTCKPGAKVAFVNDNVRYAGEIIPVDFLSTKIAEDIGFKPIKIYTLKQRKGNSSQQMGKYGRVALRKSITIWEKP
What is the function of this protein?
An alpha subtype methylase that recognizes the double-stranded sequence 5'-CYCGRG-3', methylates C-1 on both strands, and protects the DNA from cleavage by the BsoBI endonuclease.
What are the official names of this protein?
Type II methyltransferase M.BsoBI, M.BsoBI, Modification methylase BsoBI, N(4)- cytosine-specific methyltransferase BsoBI.
What is the protein family that this protein belongs to?
Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.
Protein: DTD_MANSM
Sequence: MIALIQRVSQAKVDVNGQTVGQIGGGLLVLLGVEKEDSKEKADKLAEKVLNYRIFGDKNDKMNLNVQQTDGELLVVSQFTLAADTGRGLRPSFSKGAPPQLANELYQYFVQKCGEKVRVETGKFAENMQVSLTNDGPVTFWLKV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PVK1_EPICH
Sequence: QGLIPFPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-1.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RPB1_ASFK5
Sequence: MEAGYAEIAAVQFNIAGDNDHKRQGVMEVTISNLFEGTLPAEGGIYDARMGTTDHHYKCITCSHQRKQCMGHPGILQMHAPVLQPLFIAEIRRWLRVICLNCGAPIVDLKRYEHLIRPKRLAEAASSQTEGKQCYVCKVIHPKIIKDSEDYFTFWVDQQGKIDKLYPQIIREIFSRVTYDTVVKLGRSKNSHPEKLVLKAIQIPPISIRPGIRLGIGSGPQSFHDINNVIQYIVRKNLLIPKDLQIVRGQKIPLNVDRNLQTIQQLYYNFLLDSVSTTATQGGTGKRGIVMGARPAPSIMRRLPRKEGRIRKSLLGSQVWSISRSTICGNSDLHLDEVGYPISFARTLQVAETVQHYNINRLMPYFLNGKRQYPGCSRVYKQITQSVHDIEGLKQDFRLEVGDILYRDVVTGDVAFFNRQPSLERSSIGVHRIVVLENPKISTFQMNVSACAWYNADFDGDQMNLWVPWSVMSRVEAELLCSVRNWFISTKSSGPVNGQVQDSTVGSFLLTRTNTPMGKNVMNKLHAMGLFQTTQTDPPCFANYSPTDLLDGKLVVSMLLKQTPINYQRAPTWYSEVYAPYMHYNKQDISTQIRNGELIEGVLDKKAVGAGSSGGIYHLISRRYGPQQALKMIFATQQLALNYVRNAGFTVSTADMLLTPEAHQEVQEIINELLLESEEINNRLLHGDIMPPIGLTTHDFYEKLQLNALKFPDRILKPIMNSINPETNGLFQMVATGAKGSNPNMIHIMAGIGQIEINTQRIQPQFSFGRTLVYYPRFALEAQAYGFICNSYIAGLTSPEFIFGEMNGRFDLINKALSTSSTGYANRKAIFGLQSCIVDYYRRVSIDTRLVQQLYGEDGLDARQLETVRFETIMLSDQELEDKFKYTGIQSPLFEEEFSRLKKDRDKYRQIFLNIENFNFSQLLTDVRQVPVNVASIVKNILLSSTSGVLPFDEKSILQKYTMVKTFCKNLPYVFINNIQERLQTPIPVYLKRAASLMRILIRIELATVKTLNITCEQMSAILDLIRLQYTQSLINYGEAVGILAAQSVSEPLTQYMLDSHHRSVAGGTNKSGIVRPQEIFSAKPVEAEQSSEMLLRLKNPEVETNKTYAQEIANSIELITFERLILQWHLLYETYSSTKKNVMYPDFASDVEWMTDFLENHPLLQPPEDIANWCIRLELNKTTMILKSISLESIVNSLRAKHPNTYIMHSVENTASGIPIIIRIYLRESAFRRSTNTRMATDEKIAVNLVDKLLNSTIRGIPGIKNANVVKLMRHRVDAQGKLVRLDNIYAIKTNGTNIFGAMLDDNIDPYTIVSSSIGDTMELYGIEAARQKIISEIRTVMGDKGPNHRHLLMYADLMTRTGQVTSLEKAGLNAREPSNVLLRMALSSPVQVLTDAAIDSAVNPIYGIAAPTLMGSVPRIGTMYSDIIMDEKYITENYKSVDSMIDML
What is the function of this protein?
Catalytic component of the DNA-directed RNA polymerase (RNAP) that catalyzes the transcription in the cytoplasm of viral DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity).  Forms the polymerase active center together with RPB2 (By similarity).  Part of the core element with the central large cleft, the clamp element that moves to open and close the cleft and the jaws that are thought to grab the incoming DNA template (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase RPB1 homolog.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
What are the subcellular locations of this protein?
Virion. Note=Found in association with viral nucleoid.
Protein: MNTH_CHRSD
Sequence: MRTGSMLRTISDSAIRDQAASTLSGKPRRWSWTAFFGPALIAAVAYIDPGNFATNIEAGSRYGYTLLWVVLAANLMAMLIQTLSARLGLATGQNLPQVIRARYPRPLVWCYWVQAEIVAIATDLAEFLGAALAFHLLFGLSLMEGALLTGTITYLALHLYRYGFRLMEILIGAMILAVAGGFILELVLSRPEPAPLLKGLLIPGFPDGYALYLAAGILGATVMPHVIYLHSALSQQRIQVKDDAHRLRLMRYYRLDVILGMAIAGLVNLSMLAMAAAVFHATGRLDVATISDSYLLLAPVVGQVTASHVFGLALLLAGLSSSIVGTLSGQVIMQGFVNVSIPLWLRRLVTMLPALAVIMLGISEQKALVASQVILSFGIPFALVPLLCFTANRQIMGNLVNRKSVTGVGTVVCTLIVALNVYVLFSTFTGH
What is the function of this protein?
H(+)-stimulated, divalent metal cation uptake system.
What are the official names of this protein?
Divalent metal cation transporter MntH.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TILS_BORPA
Sequence: MSTSTAAPAPSLSDLCPAALRRPVAAALRALDPAPARLAVAVSGGADSAMLAVAAAAVLPPGCTLRLFHVHHGLQAAADQWAAQVRGLGALLGVPVDEARVTVPPGQGLGMEAAARLARYQALAGLARQHGVRHILLAHHRNDQAETVLLRLLRGTGLQGMAAMAPLSERDGVAYLRPWLDVDRAAILALAGAVRAQCGWQAVQDPTNTDPRYARAAVRTQLAPALDARWPGWQAIVARHARQMAEAAEIVAEVARADFDTLEPADAGRSFSLAAWRGLSAARQAQALRHWLASQDAPMPTEARLAELQRQLRQLHALGHDRHLRWQHAGRVVRCERGRVWIDD
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLIT_SALA4
Sequence: MTSTVEFINRWQRIALLSQSLLELAQRGEWDLLLQQEVSYLQSIETVMEKQTPPGITRSIQDMVAGYIKQTLDNEQLLKGLLQQRLDELSSLIGQSTRQKSLNNAYGRLSGMLLVPDAPGAS
What is the function of this protein?
Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD.  As a transcriptional regulator, acts as an anti-FlhDC factor; it directly binds FlhC, thus inhibiting the binding of the FlhC/FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons.  As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus.
What are the official names of this protein?
Flagellar protein FliT.
What is the protein family that this protein belongs to?
Belongs to the FliT family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: URE3_BORPE
Sequence: MELTPREKDKLLIFTAALLAERRRARGLKLNYPETVALITAALMEGARDGKTVAELMSEGTRILGRDEIMEGVPEMISNIQVEVTFPDGTKLITVHNPVV
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURB_RICCK
Sequence: MMTLPIVKGEYKKDYNLKHLTWFKVGGNAEIFFKPFDSEDLASFLRQNKQKLPITTFGAGSNIIIRDGGIEGVTIKLGQSFSNIDFIDDNHLVVGSSCLNYNLAKFCQANAISGFEFLVGIPGTIGGGAAMNAGAYGSEFKDIIVRIEAIDFAGNFLTFTNEEIGFKYRSNNLPKNLIILKAIFKVNKGDSENILLRMNEINATRSRTQPIKERTGGSTFANPEGGLKSWQLIDKAGLRGYRIGGASVSELHCNFMINNGDATAKDLEDLGNFVRQNVFEDSGVKLNWEIKRIGKYV
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UDG_STRP1
Sequence: MKIAVAGSGYVGLSLGVLLSLQNEVTIVDILPSKVDKINNGLSPIQDEYIEYYLKSKQLSIKATLDSKAAYKEAELVIIATPTNYNSRINYFDTQHVETVIKEVLSVNSHATLIIKSTIPIGFITEMRQKFQTDRIIFSPEFLRESKALYDNLYPSRIIVSCEENDSPKVKADAEKFALLLKSAAKKNNVPVLIMGASEAEAVKLFANTYLALRVAYFNELDTYAESRKLNSHMIIQGISYDDRIGMHYNNPSFGYGGYCLPKDTKQLLANYNNIPQTLIEAIVSSNNVRKSYIAKQIINVLEERESPVKVVGVYRLIMKSNSDNFRESAIKDVIDILKSKDIKIIIYEPMLNKLESEDQSVLVNDLENFKKQANIIVTNRYDNELQDVKNKVYSRDIFNRD
What is the function of this protein?
Catalyzes the formation of UDP-glucuronic acid which is required for capsular hyaluronic acid synthesis.
What are the official names of this protein?
UDP-glucose 6-dehydrogenase, UDP-Glc dehydrogenase, UDP-GlcDH, UDPGDH.
What is the protein family that this protein belongs to?
Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
Protein: ASIP_MACFA
Sequence: MDVTRLLLATLLVFLCFFTAYSHLPPEEKLRDDRSLRSNSSVNLLDFPSVSIMALNKNSKEISRKEAEKKRSSKKEASMKKVARPRTPLSAPCVATRDSCKPPAPACCDPCASCQCRFFRSACSCRVLSLNC
What is the function of this protein?
Involved in the regulation of melanogenesis.  The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity).
What are the official names of this protein?
Agouti-signaling protein, ASP, Agouti switch protein.
What are the subcellular locations of this protein?
Secreted.
Protein: RS2_THEVO
Sequence: MEEEMLIPEEEYQKSGVHIGTQVKSSDMKPYIFKIRNDGLYILDVKKTNSKLIAAGKMLARFDPQDILVVAQRQYAFRPVAKFAEVTGAVSITGRFNPGTLTNPSLKFYKEVKVIVVTDPLADVQAMKEAIKIGIPIIALCDANNKTDFVDLVIPTNNKGRRSLAVIYWLLAREILKNRGTITSYDQFKYTIDDFEAQI
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: TATA_SHEB2
Sequence: MGGISIWQLLIVALIVVLLFGTKKLRSLGGDLGGAVKGFKNAMSSEEDKKALEDTEAAKTAQTTQQATEKKPESNKEQA
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: TMM18_RAT
Sequence: MASPYSVRVFPVSIPAVIMETDWTEPWLLGLLAFHLLCLLLTCFSAQRYKLQIGHFLCLVVLVYCAEYINEVAAMNWRLFAKYQYFDSRGMFISLVFSAPLLFNAMVIVIMWVRKTLTVMSDLKNLQERRKERKRRRKEE
What is the function of this protein?
Transcription repressor.  Sequence-specific ssDNA and dsDNA binding protein, with preference for GCT end CTG repeats (By similarity).  Cell migration modulator which enhances the glioma-specific migration ability of neural stem cells (NSC) and neural precursor cells (NPC).
What are the official names of this protein?
Transmembrane protein 18.
What is the protein family that this protein belongs to?
Belongs to the TMEM18 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus membrane; Multi-pass membrane protein.