PharMolix/UniProtQA huggingface dataset:
Protein: RL14_PROMM
Sequence: MIQQESFLTVADNSGAKRIQCIRVLGSNRRYAHVGDVIVAAVKDAMPNMSVKKSEVVKAVVVRTKATLRRDTGNSIRFDDNAAVLINEDKNPRGTRVFGPVARELRERNFTKIVSLAPEVI
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RUVC_ENT38
Sequence: MSIILGIDPGSRITGYGVIRQVGRQLTYLGSGCIRTKVDDLPSRLKLIYAGVSEIITQFQPDFFAIEQVFMAKNADSALKLGQARGVAIVAAVNQDLPVFEYAARQVKQTVVGTGGAAKSQVQHMVRTLLKLQANPQADAADALAIAITHCHVTQNSMQMSESRLSLARGRLR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: ORC3_DICDI
Sequence: MAGENYCSVCEGIISTENDLAVCYKCKEEIFHKACGKKVFDSLRCLNCGPIEKRSLSHQIGEISKGKAKLETRTSRFTGINVTKEFIESGEYGISKGDDDDDGDYVGGDDSSSDDEYFGNPTVLNNYPTTMNNVDLNFPTFFLLNEDMKKRKQKIKEDGNNEEIKKIEQEEKMIIQEYQNEEILKFFGDRSCFKQTQLAYEAMVQCLKDLKESIERMFKVVSVKTLGDISSFISMSYPKKSLLDIRDIALELIGQSIDDSIHHIPTSILYTSSSSPEVAQLFQSVPSNVMMRIKSHQPFSSDISSHLCEPPTITLNPDCCNTFKSTVSTICHSLTKDYDVTKFPSPHFEDLSRWYSNYFSIPLIQEVIELFKQQQQQQQQQQQQQQQQQQQQQQQQQQQQQKDKLEEIMLVRTPVILVIEDFETWNSEVLSDLIHLLSAYRHRIPFVLSFSISTSADAIHKVLPYQVVSLLNLKSLHLRSQNEMFEQLVKHLFLKSQPYIISKKAYLYLYYNFKNSYMSLSTTISVLRHFIIDHFLENGLSYLTLDLSNFQIDLKDDDDDMDGCSTIKLEPENDSTDSTVNDEVGTGDNIDNDNVSTHGEEDTPDSLVKSDIECQTLSYSSDDERNDYDTSTDSDNCSNFHKKKPNSNNRIKSDLECNDNDKDNDDNDNDINENNNNINNNNNNNSNNDDNDKDSFGPKRIPNQRFVTLIQKLPSLNTDEIENSKISTNRKLNKLQSNLIIFKESRPIMLELYYTILSKFQKSKTLKYSELLKKISLNDRKSYETLRKTILTNPESKQSIETLLDLLKTSRHHFERIIKATNSLKLFQTPKSKKYQDLVKIENLILKCRTLSNNFKNLLLPPDEQSKSIKNEIKQQQQQQQQQQQQQQQQQHQQQQKIENEQKNWSIKKKREHQLRNIQKPTDSYFKIYSREFLDDIVSVIIEDYLYPPLVSVPLSEIFDFTQTVFITQSRFNFHTAEGINDNLIHSVRKLKCECCIDSLCGTMDDFSISFILLLRSGRYINYFDWLTSFCSIINGDNNPTPNLKARFIKSVDTFVSLELIKKTRKRKDHFEKIAFLTTS
What is the function of this protein?
Component of the origin recognition complex (ORC) that binds origins of replication.  DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far.  ORC is required to assemble the pre-replication complex necessary to initiate DNA replication (By similarity).
What are the official names of this protein?
Origin recognition complex subunit 3, Origin replication complex subunit C.
What is the protein family that this protein belongs to?
Belongs to the ORC3 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RECR_BIFLD
Sequence: MALAYDGAIQRLIDAFGRLPGIGPKGAQRIAFYMLSAPEDEARDLAEAIEEVKAKIRFCDICGNVCESSPCPVCADPRRDRSVICVVEEPKDVMSIERTREYHGLYHVLGGAINPMANVGPADLRIPGLLKRLEGDEVKEVIMALDPNIEGEATTSYLTQLLRPVGVKVTRLASGLPVGSDLEYADEITLGRALAGRREA
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: GSA1_STAAE
Sequence: MRYTKSEEAMKVAETLMPGGVNSPVRAFKSVDTPAIFMDHGKGSKIYDIDGNEYIDYVLSWGPLILGHRDPQVISHLHEAIDKGTSFGASTLLENKLAQLVIDRVPSIEKVRMVSSGTEATLDTLRLARGYTGRNKIVKFEGCYHGHSDSLLIKAGSGVATLGLPDSPGVPEGIAKNTITVPYNDLDALKIAFEKFGNDIAGVIVEPVAGNMGVVPPIEGFLQGLRDITTEYGALLIFDEVMTGFRVGYHCAQGYFGVTPDLTCLGKVIGGGLPVGAFGGKKEIMDHIAPLGNIYQAGTLSGNPLAMTSGYETLSQLTPETYEYFNMLGDILEDGLKRVFAKHNVPITVNRAGSMIGYFLNEGPVTNFEQANKSDLKLFAEMYREMAKEGVFLPPSQFEGTFLSTAHTKEDIEKTIQAFDTALSRIVK
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase 1, GSA 1, Glutamate-1-semialdehyde aminotransferase 1, GSA-AT 1.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENLYS_BPPZA
Sequence: MQISQAGINLIKSFEGLQLKAYKAVPTEKHYTIGYGHYGSDVSPRQVITAKQAEDMLRDDVQAFVDGVNKALKVSVTQNQFDALVSFAYNVGLGAFRSSSLLEYLNEGRTALAAAEFPRWNKSGGKVYQGLVNRRAQEQALFNSGTPKNVSRGTSSSKVTPKYKVKSGDNLTKIAKKHNTTVATLLKLNPSIKDPNMIRVGQTINVTGSGGKTHKVKSGDTLSKIAVDNKTTVSRLMSLNPEITNPNHIKVGQTIRLS
What is the function of this protein?
Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles.  Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.
What are the official names of this protein?
Endolysin, Lysis protein, Lysozyme, Muramidase, Protein p15.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 24 family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=The endolysin is cytoplasmic, but can reach the periplasmic space with the help of the holins which disrupt the host cell membrane.
Protein: SCX8_CENLI
Sequence: TVSAKEGYLVKKSNGCKYECFKLGENEHCDTECKAPNQGGSYGYCDTFECWCEGLPESTPTWPLPNKSCGKK
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
What are the official names of this protein?
Toxin Cll8.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CNSL_PENEN
Sequence: MAADQVTISDEPKGGGVTADAAVKAIKAGRNKDVDIAAQIVSDYADQMDGDTWSVEEERKLIRRIDWRLIPTLFVCATLSGLDKTAISAAAVYNIKTDLNLTGAEYSWIGSAPFFGGLLFMGPLAYCLQRVPAVPFFAFNVLCWGILEMSVTMVVSMWYRPEEQPKRNSIILNVVAPIINGFVAWVVGYYKGPYERWKIIFLLVGALTIVTSVVVYFVLPNNPLEAKFLTPREKYIVIQRKAADNTGIESKTFKMEQVWEAIFDIKTWLIWIAIAALQVPNGGLTTFNTLIISGLGFDSLQTSLLAMPPGAMSTLSGIGLSYLAATTRRYRTAIVTVSILLPLFGAVLCYALPRTNLAGQLVGLYILYTYWAPYVTLVSVYQANVAGHTKKITLYAWFYIAWATGNIIGPQTFRADQAPEYTGGTVAMIICYVVAMFAITAYGVVCHLSNKKRAEAIEARTAADHDWLDMTDKENVGFKYTT
What is the function of this protein?
MFS-type transporter; part of the gene cluster that mediates the biosynthesis of communesins, a prominent class of indole alkaloids with great potential as pharmaceuticals (PubMed:25571861).  With the MFS transporter cnsO, is most likely responsible for cummunesins secretion and thereby may contribute to intrinsic resistance (Probable).
What are the official names of this protein?
MFS-type transporter cnsL, Communesin biosynthesis cluster protein L.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Allantoate permease family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DER_CHLTE
Sequence: MKPLIALVGRPNVGKSTLFNRILRQKSAIVDPTPGVTRDRHISPGEWQGKQFLLMDTGGYAPENDTLSKAMLEQTMRAIEDADAVIFIVDARSGLTYLDLDIAKILQKTFKDKKIFFVANKVDNPQVALEAQSLVKSGFTEPYLISARDGAGVADMLEDVLNSLPCPEGEEIEEDDSIKLAVLGRPNVGKSSLVNALLGTERHIVSDVPGTTRDAIDSVLKRNGEEYVLIDTAGLRKRTKIDAGIEFYSSLRTARAIERCDVALVLLDARLGLESQDMKIIHMAIERKKGVLILVNKWDLVEKDSKTSKAFTDNLQNQLGNIGYIPVIFTSALTKKNCYRAIDTAAEIALNRRQKISTSNLNRFLQETLTMRHPATKSGKELKIKYMTQIDSDHPVFAFFCNDPELLENNFRRFLEKRLRESFDFAGIPITMRFLRK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: OLCH_PENCN
Sequence: MVTKCIDPCEQQNQKRPVGHLVWDLIRISRYDKYNSFLALFSGVWSTLLAGALKLRNEPESTSVSFVLSRVVLCSLASYIFSGAGMVWNDWVDRDIDAKVARTKDRPLASGRLHTMEAMAWLIIQVAASTGLLYWMMEGRHVWISLVPPAIGTLLYPYCKRPTAQKFGIYPQYVLGLTAACPAVFGRAAIYNHEDSFQDLINASFPLCLFVFVWTLYFNTAYSYQDVKDDSKMKINSSYVFAGQHIHLFLVLLTGLVLASIPWVLHPLQSGWLWVSWMGVWSVGCAEQLVRFNANDPHTGGLVWRRNILLALWTIFACLVEVLLVWIHQI
What is the function of this protein?
Polyprenyl transferase; part of the gene cluster that mediates the biosynthesis of 15-deoxyoxalicine B (PubMed:30090271).  The first step of the pathway is the synthesis of nicotinyl-CoA from nicotinic acid by the nicotinic acid-CoA ligase olcI (PubMed:30090271).  Nicotinyl-CoA is then a substrate of polyketide synthase olcA to produce 4-hydroxy-6-(3-pyridinyl)-2H-pyran-2-one (HPPO) which is further prenylated by the polyprenyl transferase olcH to yield geranylgeranyl-HPPO (PubMed:30090271).  Geranylgeranyl pyrophosphate is provided by the cluster-specific geranylgeranyl pyrophosphate synthase olcC (PubMed:30090271).  The FAD-dependent monooxygenase olcE catalyzes the epoxidation of geranylgeranyl-HPPO and the terpene cyclase olcD catalyzes the cyclization of the terpenoid component, resulting in the formation of the tricyclic terpene moiety seen in predecaturin E (PubMed:30090271).  The cytochrome P450 monooxygenase then catalyzes the allylic oxidation of predecaturin E, which is followed by spirocylization with concomitant loss of one molecule of water to form decaturin E (PubMed:30090271).  Decaturin E is the substrate of the cytochrome P450 monooxygenase olcJ which hydroxylates it at the C-29 position to form decaturin F (PubMed:30090271).  The short-chain dehydrogenase/reductase olcF may catalyze the oxidation of decaturin F to generate the 29-hydroxyl-27-one intermediate, and subsequent hemiacetal formation probably leads to the formation of decaturin C (Probable).  The dioxygenase olcK may be a peroxisomal enzyme that catalyzes the hydroxylation of decaturin C into decaturin A once decaturin C is shuttled into the peroxisome by the MFS transporter olcL (Probable).  Finally the cytochrome P450 monooxygenase olcB catalyzes the oxidative rearrangement to yield 15-deoxyoxalicine B (PubMed:30090271).  In the absence of olcJ, decaturin E may be shunted to a pathway in which it is oxidized to a ketone, possibly by olcF, to form decaturin D, which undergoes further allylic oxidation to yield decaturin G (PubMed:30090271).  Moreover, in the absence of oclK or oclL, oclB can convert decaturin C into 15-deoxyoxalicine A (PubMed:30090271).
What are the official names of this protein?
Polyprenyl transferase olcH, 15-deoxyoxalicine B biosynthesis cluster protein H.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: LRFN4_HUMAN
Sequence: MAPPLLLLLLASGAAACPLPCVCQNLSESLSTLCAHRGLLFVPPNVDRRTVELRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELGTGSLRGPVNLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDHNLIDALPPGAFAQLGQLSRLDLTSNRLATLAPDPLFSRGRDAEASPAPLVLSFSGNPLHCNCELLWLRRLARPDDLETCASPPGLAGRYFWAVPEGEFSCEPPLIARHTQRLWVLEGQRATLRCRALGDPAPTMHWVGPDDRLVGNSSRARAFPNGTLEIGVTGAGDAGGYTCIATNPAGEATARVELRVLALPHGGNSSAEGGRPGPSDIAASARTAAEGEGTLESEPAVQVTEVTATSGLVSWGPGRPADPVWMFQIQYNSSEDETLIYRIVPASSHHFLLKHLVPGADYDLCLLALSPAAGPSDLTATRLLGCAHFSTLPASPLCHALQAHVLGGTLTVAVGGVLVAALLVFTVALLVRGRGAGNGRLPLKLSHVQSQTNGGPSPTPKAHPPRSPPPRPQRSCSLDLGDAGCYGYARRLGGAWARRSHSVHGGLLGAGCRGVGGSAERLEESVV
What is the function of this protein?
Promotes neurite outgrowth in hippocampal neurons.  May play a role in redistributing DLG4 to the cell periphery (By similarity).
What are the official names of this protein?
Leucine-rich repeat and fibronectin type-III domain-containing protein 4.
What is the protein family that this protein belongs to?
Belongs to the LRFN family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RS8_BARHE
Sequence: MSMSDPLGDMLTRIRNALARKKGKVVTPASKLRARVLDVLQSEGYIRGYNQVDLGDGKSEIEIELKYFEGLAAIREISRVSKPGRRVYVSAKSIPHVANGLGISILSTPKGVMADYEARKQNVGGELLCRVF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: Y2975_GLOC7
Sequence: MFTIDIILQMSPIPVSVQRKDEESAQSLYQSITQAMQEPNPKLIELTCDKQPDKKVAIFSNQISAVIVSEKTGAAAAGRAPGFLAIGEI
What are the official names of this protein?
UPF0367 protein PCC7424_2975.
What is the protein family that this protein belongs to?
Belongs to the UPF0367 family.
Protein: FABZ_BACAH
Sequence: MLNIEQIKEIIPHRYPFLLVDKILEVDEGKRAVGIKNVSANEEFFNGHFPDYAVMPGVLIVEALAQVGAVAVLKKEENRGRLAFFAGIDNCRFKKQVRPGDQLRLEVEMTRVRGPIGKGKAIATVDGEVACEAEITFAIGDKKE
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGT_ACIBY
Sequence: MKFEKLGQSGRARRGRLTLEHGVVETPVFMPVGTYGTVKGMLPRDIEDIQAQIILGNTFHLYLRPGLEVIKQHGGLHDFIKWNKPILTDSGGFQVFSLGAMRKIKEEGVTFRSPIDGSKVFLSPEISMEIQHVLNSDIVMIFDECTPYPATHEEAQKSLQLSLRWAKRCKAHHHDELKNKNALFGIIQGGMYEDLRDESLNGLLEIGFDGYAIGGLSVGEPKEEMIKVLDYLPNKMPHDKPRYLMGVGKPEDIVEAVRRGVDMFDCVMPTRNARNGHYFVTDGLVRIRNSKYRHDQGPLDPHCDCYTCKNFTRAYLFHLEKCGEMLASMLGTIHNLRYYQRLTEGMRDALDNGTFDEFVQDFYARRGLEVPPCPVDE
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: ATOX1_SHEEP
Sequence: MPKHEFSVDMTCEGCSNAVTRVLNKLGGVQFDIDLPNKKVCINSEHSVDTLLETLGKTGKAVSYLGPK
What is the function of this protein?
Binds and deliver cytosolic copper to the copper ATPase proteins.  May be important in cellular antioxidant defense (By similarity).
What are the official names of this protein?
Copper transport protein ATOX1, Copper chaperone SAH, Metal transport protein ATX1.
What is the protein family that this protein belongs to?
Belongs to the ATX1 family.
Protein: TXO1A_ETHRU
Sequence: MVKSLHCLIGIVLFLAILNAGNGFTLDRSASIERQEDSWPKISLFHGNQRKNDLKKSVSPTWNKLSRCPVYLPTKSDTIRVVQIKGYFAEKKQTIITSYCIIK
What are the official names of this protein?
U-scoloptoxin(24)-Er1a, U-SLPTX(24)-Er1a.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-24 family.
What are the subcellular locations of this protein?
Secreted.
Protein: TDH_SALDC
Sequence: MKALSKLKAEEGIWMTDVPEPEVGHNDLLIKIRKTAICGTDVHIYNWDDWSQKTIPVPMVVGHEYVGEVVGIGQEVKGFKIGDRVSGEGHITCGHCRNCRGGRTHLCRNTTGVGVNRPGCFAEYLVIPAFNAFKIPDNISDDLASIFDPFGNAVHTALSFDLVGEDVLVSGAGPIGVMAAAVAKHVGARHVVITDVNEYRLELARKMGVTRAVNVAKESLNDVMAELGMTEGFDVGLEMSGAPPAFRTMLDTMNHGGRIAMLGIPPSDMSIDWTKVIFKGLFIKGIYGREMFETWYKMAALIQSGLDLSPIITHRFSIDDFQKGFDAMRSGQSGKVILSWD
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRE_PSEPG
Sequence: MQPYQRDFIRFAIDRGVLRFGEFTLKSGRTSPYFFNAGLFNTGSALAELGRCYAAAIVDSKIPFDVLFGPAYKGIPLAATTAVALADQHQLDVPWCFNRKEAKDHGEGGSLVGAPLAGDVLIIDDVITAGTAIREVMQIINAQQAKAAGVLIALNREERGNGELSAIQEVERDFGIPVVSIVSLTQVLEFLADDPQLKQHLPAVEAYRAQYGI
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: KDPC_SALSV
Sequence: MIGLRPAFSTMLFLLLLTGGVYPLLTTALGQWWFPWQANGSLIHKDNVIRGSALIGQSFTAAGYFHGRPSATADTPYNPLASGGSNLAASNPELDAQIQARVAALRAANPQASSAVPVELATASASGLDNNLTPGAAAWQIPRVAAARQLPVEQVAQLVAEYTHRPLASFLGQPVVNIVKLNLALDALQGHRAK
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: SUCC_HALS3
Sequence: MKLHEYQAKEVFADAGIPTPESALATSVDEAVEVADALDYPVAVKAQVHVGGRGKAGGIKLAENTAEAREAAESILGMDLKGYTVDRVLVEEAVDFTNELYVGVTMDRSEGAPVVMVSERGGVDIESVAEEAPEDIVREHVDPSFGLQAYQARNAVYDAGIEQDVAGDVAKIVQGVYDLWADSDATEVEINPVMVTSERDVVAADAVMKLDEDALFRQPAFADMEEDAAEDDLEAKANEYGFDYVRLDGNTGIIGNGAGLVMTTLDLVDYYGGQPANFLDIGGGAKADRVANALDMVFSDENVDSVVFNIFGGITRGDEVAKGINSALEQFDEIPTPVVVRLAGTNAAEGREILNDDLVTVEETLEGAVQRAVEYADEEDIQ
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: TTCA_PSEPG
Sequence: MGTLSVNQNKLQKRLRRLAGEAITDYNMIEDGDKVMVCLSGGKDSYTMLDVLLHLQKVAPIKFEIVAVNMDQKQPGFPEHVLPAYLKELGVEYHIVEKDTYSVVKELVPEGKTTCSLCSRLRRGTLYTFADEIGATKMALGHHRDDIVETFFLNMFFNGALKGMPPKLRADDGRNVVIRPLAYCSEKDIQAYSDMKEFPIIPCNLCGSQENLQRQVVKDMLVEWERKHPGRTESIFRALQNVAPSQLADRNLFDFTSLKIDENATPRFLDVLNI
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPX_CLOBJ
Sequence: MSKLDEKKQLKCSFCGKTQDQVRRLIAGPGVYICDECIELCSEIINDEFEDDIQVDLTSLPKPTEIKTYLDQYVIGQEDAKKSLSVAVYNHYKRINSNTNNDDVELQKSNILLLGPTGSGKTLLAQTLAKFLNVPFAIADATTLTEAGYVGEDVENILLKLIQNADYDIEKAEKGIVYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVAAVPPQGGRKHPHQEFIQINTTNILFICGGAFDGVDKIIERRTRTSSLGFGAEIQSKKEKDLGKLLKDIMPGDLLKFGLIPEFIGRLPIVVTLDKLDREALIKILTEPKNALVKQYKKLFELDDVELEFNQEALKEIADEAINRNTGARGLRAIIEDMMREIMFDIPSQENIGKVIVNEDCIKTKKPELIEAEGGKRLPIKPKKGKKRKDSETA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: RL15_BOVIN
Sequence: MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNFH_PROMH
Sequence: MTKIWVEVAYALPDKQYVIPVELTLGDTVEQAIIASNILTICNDIDLTKNKVGIYSRPAKLSDNVRDGDRVEIYRPLIADPKEMRRKRAEKARQKTE
What are the official names of this protein?
Protein RnfH.
What is the protein family that this protein belongs to?
Belongs to the UPF0125 (RnfH) family.
Protein: RNFH_CROS8
Sequence: MPGEIQVEVAYALPEKQYLRKVKLPEGASVEEAIIASGLLELRKDIDLKKNKVGIYSRPVKLADTLNDGDRVEIYRPLIADPKELRRQRAERAAKK
What are the official names of this protein?
Protein RnfH.
What is the protein family that this protein belongs to?
Belongs to the UPF0125 (RnfH) family.
Protein: ARGP_SALDC
Sequence: MKRPDYRTLQALDAVIRERGFERAAQKLCITQSAVSQRIKQLENMFGQPLLVRTVPPRPTEQGQKLLALLRQVELLEEEWLGDEQTGSTPLLLSLAVNADSLATWLLPALAPVLADSPIRLNLQVEDETRTQERLRRGEVVGAVSIQHQALPSCLVDKLGALDYLFVASRPFAERYFPNGVTRSSLLKAPAVAFDHLDDMHQAFLQQNFDLPPGSVPCHIVNSSEAFVQLARQGTTCCMIPHLQIEKELESGELINLTPGLLQRRMLYWHRFAPESRMMRKVTDALLEYGHKVLRQD
What is the function of this protein?
Controls the transcription of genes involved in arginine and lysine metabolism.
What are the official names of this protein?
HTH-type transcriptional regulator ArgP.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.