PharMolix/UniProtQA huggingface dataset:
Protein: KEG1_YEAST
Sequence: MAGIKLTHKLYQYYQLATSFLYAALLIRWLILMPLVGSRFLPGGIHEFLIYLMFYSSIMEVIWLLRFHGFKYGLLSRTFLKDLNFIYLVSVIHFYDDYEHALILKNASYSSFIISLSLSQAYCHWCKLFKRKGVKERTLVWKVNTFVTLPILYLSEFALLLLNIQVKNYHSTPTLDIINRVVLLAYFPVLLTAYKKLLTK
What is the function of this protein?
Involved in the biosynthesis of (1->6)-beta-D-glucan polymers of the cell wall.  Required for viability.  Involved in maintaining chromosome stability.
What are the official names of this protein?
Beta-1,6-glucan synthesis-associated protein KEG1, KRE6-binding ER protein responsible for glucan synthesis protein 1.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: YPEL5_MACFA
Sequence: MGRIFLDHIGGTRLFSCANCDAILTNRSELISTRFTGATGRAFLFNKVVNLQYSEVQDRVMLTGRHMVRDVSCKNCNSKLGWIYEFATEDSQRYKEGRVILERALVRESEGFEEHVPSDNS
What is the function of this protein?
Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1 (By similarity).  Required for normal cell proliferation (By similarity).
What are the official names of this protein?
Protein yippee-like 5.
What is the protein family that this protein belongs to?
Belongs to the yippee family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Midbody. Note=Deteted in nucleus and at the centrosome during interphase. During mitosis, detected on the mitotic spindle, at spindle poles and at the midbody.
Protein: LPXC_NEIM0
Sequence: MLQRTLAKSISVTGVGLHSGERVALTLHPAPENSGISFRRTDLDGEMGEQIKLTPYLINDTRLSSTIVTDKGVRVGTIEHIMSALSAYGIDNALIELNAPEIPIMDGSSLPFIYLLQDAGVVDQKAQKRFLKILKPVEIKEAGKWVRFTPYDGFKVTLTIEFDHPVFNRSSPTFEIDFAGKSYIDEIARARTFGFMHEVEMMRAHNLGLGGNLNNAIVIDDTDVLNPEGLRYPDEFVRHKILDAIGDLYIVGHPIVGAFEGYKSGHAINNALLRAVLADETAYDRVEFADSDDLPDAFHELNIRTCG
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: MGLL_SCHPO
Sequence: MADLYTKDWTDVKDKPVARVVFIHGFGEHVNAYPEFFEALNERNIEVYTFDQRGFGHSRKGGPKKQGCTGGWSLVFPDLDYQILRASDTELPLFLWGHSMGGGLALRYGISGTHRHKLAGVIAQAPMLRCHPDTEPNFLLRKALTLVSKVHPNFLFDSDVQSQHITRDEAVNQRLQDDPLVSSVGSLQVFSDMLNRGTKTIELAPQFFLPLLITHGTDDNVTCSDSSKEFYENAGTKDKTYQSYPGFYHSLHIEKKPEVYEYLDKVAAWIYEHSKPSETVKSEQETAVEHPKPTATTSAPSASPTGVPVEEESHKATSDAVPPAEAKPEPVPASAAERAPTSESTTVPETIVASTTKVISEPAPRVTTAATADIVTNK
What is the function of this protein?
Converts monoacylglycerides (MAG) to free fatty acids and glycerol.  Has a strong preference for monounsaturated monoglycerides.  Required for efficient degradation of MAG, short-lived intermediates of glycerolipid metabolism which may also function as lipid signaling molecules.  Controls inactivation of the signaling lipid N-palmitoylethanolamine (PEA).  Involved in fatty acid ethyl ester (FAEE) catabolism.  FAEEs are non-oxidative metabolites of ethanol that are transiently incorporated into lipid droplets (LDs).  Their mobilization by LD-resident FAEE hydrolases facilitates a controlled metabolism of these potentially toxic lipid metabolites.
What are the official names of this protein?
Putative monoglyceride lipase, MGL, Fatty acid ethyl ester hydrolase, FAEE hydrolase, Monoacylglycerol hydrolase, MAG hydrolase, MGH, Monoacylglycerol lipase, MAG lipase, MAGL.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Monoacylglycerol lipase family.
What are the subcellular locations of this protein?
Lipid droplet. Cytoplasm. Endoplasmic reticulum. Mitochondrion outer membrane. Note=Although the protein is identified in the cytoplasm, several membrane systems and lipid droplets, MGL activity is only measured in membrane fractions and lipid droplets.
Protein: HSP83_TRYBB
Sequence: MTETFAFQAEINQLMSLIINTFYSNKEIFLRELISNSSDACDKIRYQSLTNQSVLGDEPHLRIRVIPDRVNKTLTVEDSGIGMTKADLVNNLGTIARSGTKSFMEALEAGGDMSMIGQFGVGFYSAYLVADRVTVVSKNNEDDAYTWESSAGGTFTVTSTPDCDLKRGTRIVLHLKEDQQEYLEERRLKDLIKKHSEFIGYDIELMVENTTEKEVTDEDEDEEAAKKAEEGEEPKVEEVKDGVDADAKKKKTKKVKEVKQEFVVQNKHKPLWTRDPKDVTKEEYASFYKAISNDWEEQLSTKHFSVEGQLEFRAILFLPKRAPFDMFEPNKKRNNIKLYVRRVFIMDNCEDLCPEWLGFLRGVVDSEDLPLNISRENLQQNKILKVIRKNIVKKALELFEELAGNKEDYKKFYEQFSKNVKLGIHEDSTNRKKLMELLRFHSSESGEEMTTLKDYVTRMKEGQKCIYYVTGDSKKKLETSPFIEQARRRGMEVLFMTDPIDEYVMQQVKDFEDKKFACLTKEGVHFEETEEEKKQREEEKASYERLCKAMKEVLGDKVEKVVVSDRLATSPCILVTSEFGWSAHMEQIMRNQALRDSSMSAYMMRKKTMEINTTHAIVKELKRRVEADENDKAAKDLIFLLFDTSLLTSGFTLDDPTAYADRIHRMIKLGLSLDDDAEEEEAQAPVAAAANSSTGASGMEEVD
What is the function of this protein?
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction.  Undergoes a functional cycle that is linked to its ATPase activity.  This cycle probably induces conformational changes in the client proteins, thereby causing their activation.  Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity).
What are the official names of this protein?
Heat shock protein 83.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM6_RHIL3
Sequence: MERPELPIGLPDDIEEKKAAARNWFEGLRDTICASFEAIEDDLEGPLSDQEPGRFVAKDWSRENGAGGGGRMSMMEGRVFEKVGVHTSTVYGEFAPDFRAQIPGAKDDPRFWASGISLIAHPVNPNVPAVHMNTRMVVTTSRWFGGGADLTPVLSRRRTQEDEDSQLFHKAMEIACRNHAVADYDAYKTWCDEYFFLKHRNEARGIGGIFYDWLHSSEEAGGWDADFAFTRDVGRAFAMVYPKIVRSNFNKLWTEADRDEQLIRRGRYVEFNLLYDRGTIFGLKTGGNVESILSSLPPVVRWP
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1336_HAEI8
Sequence: MEIVNKQSFQEVLEYVRMYRLKNRIKRDMEDNNRKIRDNQKRILLLDNLNQYIRDDMTIAEVRGIIESMRDDYESRVDDYTIRNAELSKQRREASTKMKEQKKAHAELLKNAEK
What are the official names of this protein?
UPF0265 protein NTHI1336.
What is the protein family that this protein belongs to?
Belongs to the UPF0265 family.
Protein: RL11_HAEIN
Sequence: MAKKVQAYVKLQVAAGMANPSPPVGPALGQQGVNIMEFCKAFNARTESLEKGLPIPVVITVYADRSFTFVTKTPPAAVLLKKAAGIKSGSGKPNKDKVGKVTLDQVRQIAETKAADMTGATIETKMKSIAGTARSMGLVVEE
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: KCC1A_HUMAN
Sequence: MLGAVEGPRWKQAEDIRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGSMENEIAVLHKIKHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPWIAGDTALDKNIHQSVSEQIKKNFAKSKWKQAFNATAVVRHMRKLQLGTSQEGQGQTASHGELLTPVAGGPAAGCCCRDCCVEPGTELSPTLPHQL
What is the function of this protein?
Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, regulates transcription activators activity, cell cycle, hormone production, cell differentiation, actin filament organization and neurite outgrowth.  Recognizes the substrate consensus sequence [MVLIF]-x-R-x(2)-[ST]-x(3)-[MVLIF].  Regulates axonal extension and growth cone motility in hippocampal and cerebellar nerve cells.  Upon NMDA receptor-mediated Ca(2+) elevation, promotes dendritic growth in hippocampal neurons and is essential in synapses for full long-term potentiation (LTP) and ERK2-dependent translational activation.  Downstream of NMDA receptors, promotes the formation of spines and synapses in hippocampal neurons by phosphorylating ARHGEF7/BETAPIX on 'Ser-694', which results in the enhancement of ARHGEF7 activity and activation of RAC1.  Promotes neuronal differentiation and neurite outgrowth by activation and phosphorylation of MARK2 on 'Ser-91', 'Ser-92', 'Ser-93' and 'Ser-294'.  Promotes nuclear export of HDAC5 and binding to 14-3-3 by phosphorylation of 'Ser-259' and 'Ser-498' in the regulation of muscle cell differentiation.  Regulates NUMB-mediated endocytosis by phosphorylation of NUMB on 'Ser-276' and 'Ser-295'.  Involved in the regulation of basal and estrogen-stimulated migration of medulloblastoma cells through ARHGEF7/BETAPIX phosphorylation (By similarity).  Is required for proper activation of cyclin-D1/CDK4 complex during G1 progression in diploid fibroblasts.  Plays a role in K(+) and ANG2-mediated regulation of the aldosterone synthase (CYP11B2) to produce aldosterone in the adrenal cortex.  Phosphorylates EIF4G3/eIF4GII.  In vitro phosphorylates CREB1, ATF1, CFTR, MYL9 and SYN1/synapsin I.
What are the official names of this protein?
Calcium/calmodulin-dependent protein kinase type 1, CaM kinase I, CaM-KI, CaM kinase I alpha, CaMKI-alpha.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic.
Protein: RT16_CAEEL
Sequence: MRKLVIPKYYGRPSIGLALFGCTNRPFYHVCVFPDRALGRRYEGNILEQVGTFDPLPNQKNEKLVALNFGRLKYWIGERNAHISVPVLELLGLSGLFPIHPKSFIRAKDNRALIADQQLKVAAEAAEAEKVAQEQASTGAAATSHPQ
What are the official names of this protein?
Probable 28S ribosomal protein S16, mitochondrial, MRP-S16, S16mt.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RS20_PARDP
Sequence: MANTPQSKKRARQLERRTAVNKARRSRIRTFLRKVEEAIASGNAEIAREALNSAQPELMRGVTKGVIHKNTAARKMSRLSARVKALATA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: SCR11_NOTSL
Sequence: MPSYTLYYFNGRGRAEICRMLFAVASVQYQDKRIELAEWTQFKTKMPCHMLPILEIDTETQVPQSMAISRYLAREFGFYGKNNMDMFKVDCLCDSLFELFNDYMAVYNEKDAAKKTELQKRFQNTCLRVLPYMEKTLEANKGGAGWFIGDQILLCDMMTHAALENPIQENANLLKEYPKLAALRTRVAAHPKIAAYIKKRNNTAF
What is the function of this protein?
S-crystallins are structural components of squids and octopi eye lens.  Contains relatively little if any GST activity.
What are the official names of this protein?
S-crystallin SL11, Major lens polypeptide.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily.
Protein: IYD1H_CAEEL
Sequence: MKKHTHHKAYGDSTGKEPLIDLQSIKLWLNSFGNQGHSSEAVLNVLFTLGVILFVIYQVASLLHRMNKRVEKQLESRTKQRKVEVADKHVGDEMVFTDLHENVIRERMIPYRMPVINDDITLRNSQIFYEEMKMRRSCRQFSSRDVPLKVIQNLLKTAGTSPSVGNLQPWTFCVVSSDSIKTMIRKILEADERDNYVSRKKGASWVVDVSQLQDTWRRPYITDAPYLLIVCHEIFRDVHSKTERVFHYNQISTSIAVGILLAAIQNVGLSTVVTSPLNAGPDISRILRRPENESILLLLPLGYASEDVLVPDLKRKPVEHITKLY
What is the function of this protein?
May contribute to coordination of muscle contraction as regulatory subunit of the nonessential sup-9 potassium channel complex.  May act downstream of sup-10.
What are the official names of this protein?
Iodotyrosine dehalogenase 1 homolog, IYD-1.
What is the protein family that this protein belongs to?
Belongs to the nitroreductase family.
What are the subcellular locations of this protein?
Membrane; Single- pass membrane protein. Note=In body-wall muscle cells, localizes to dense body-like structures which connect the myofibril lattice to the cell membrane. Colocalizes with sup-10. Membrane localization is not essential for its activity.
Protein: PG045_VARV
Sequence: MYNSMLPMFMCNNIVDDIDDIDDIDDIDDIDDIDDIDDKASNNDDHNYVYPLPENMVYRFNKSTNILDYLSTERDHVMMAVQYYMSKQRLDDLYRQLPTKTRSYIDIINMYCDKVNNDYNRDMNIMYDMASTESFTVYDINNEVNTILMDNKGLGVRLATISFITELGKRCMNPVETIKMFTLLSHTICDDCFIDYITDISPPDNTIPNISTREYLKLIGITAIMFATYKTLKYMIG
What is the function of this protein?
Plays a role in the inhibition of host apoptosis.  Interacts with host BAX and thereby inhibits its activity.
What are the official names of this protein?
Apoptosis regulator OPG045, Apoptosis regulator Bcl-2 homolog, vBcl-2, F1L homolog.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG045 family.
Protein: PRSA2_STRP6
Sequence: MKQMNKLITGVVTLATVVTLSACQSSHNNTKLVSMKGDTITVSDFYNETKNTELAQKAMLSLVISRVFETQYANKVSDKEVEKAYKQTADQYGTSFKTVLAQSGLTPETYKKQIRLTKLVEYAVKEQAKNETISKKDYRQAYDAYTPTMTAEIMQFEKEEDAKAALEAVKAEGADFAAIAKEKTIAADKKTTYTFDSGETTLPAEVVRAASGLKEGNRSEIITALDPAISKRTYHIIKVTKKATKKADWKAYQKRLKDIIVTGKLKDPDFQNKVIAKALDKANVKIKDKAFANILAQFAKPNQKQPAQK
What is the function of this protein?
Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.
What are the official names of this protein?
Foldase protein PrsA 2.
What is the protein family that this protein belongs to?
Belongs to the PrsA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: MQO_PECCP
Sequence: MKKLLAMFFCLTVVVNAPLAMAEDAKTTEKTTDVVLIGGGIMSSTLGVYLQELQPDWSIDMVERMDNVAEESSNGWNNAGTGHSAFMELNYTPDNPDGPINISKALEITEAFEVSRQFWSYQVKNGVLNNPHSFINSVPHISFVWGDENTAFLKHRYDAMQHSTLYRGMEFSDDPNTIKEWAPLVMEGRDPAQKIAATRMPIGTDVNYGEITRQLVDAMKTKSNFALHLNSEVRDIKRNADNTWSVTYADLKNGEKESVIKAKFVFIGAGGAALQLLQKTGIPEADLYGGFPVGGEFLVTENPEIVKRHMAKVYGKASVGAPPMSVPHLDTRIFDGKPVLLFGPFATFSSKFLKNGSLWDLIGSVTFSNVMPMTHVGLDNFDLVKYLIGQVMMDDDDRFASLKEYFPNAKKEDWRLTVAGQRVQIIKKDDDKGGVLKLGTEIVSSQDGSIAALLGASPGASTAAPIMLSLLEKVFKDKVATPEWQSKLKEIVPSYGQKLDGNIEMTNKIRSYTSSTLGLDYIEVKPE
What are the official names of this protein?
Probable malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: EXD1_DROME
Sequence: MNKSDGNESFALDSLPENIRYPFGKRELEILEKQLDRIVLIYQVDTTYHSALKDIKDQKIISLLVEPSFYGRHHPTSILVVATCNGTYIFDIKALGLIFLELAKILEADQPRKVIHYSHRIADHLLHRQRISLGGIFDTFVAVCLSSNTRIPYTLPEAISLVFGLPMEKVTGGCESQRNFTARPLTHSQMRYLAKLVQLQHIMHDHLNYSHIFCAEVYRISLEFSHSYYGLRSCDVAINMAPASSFGFQLLDSFCKKADKELEQI
What is the function of this protein?
RNA-binding protein.  Inactive exonuclease.
What are the official names of this protein?
Protein Exd1 homolog, DmExd1, Exonuclease 3'-5' domain-containing protein 1 homolog, Exonuclease 3'-5' domain-like-containing protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the EXD1 family.
Protein: ISPH_WOLTR
Sequence: MEIILAEPRGFCAGVKRAVDILAITLKKYRNKRKVYVLHEIVHNKYIVEDFKRQGVIFVNSIRDIKDNRGILIFSAHGVSKNIEDKAKRKGIQVIDATCPLVSKVHKEAKRYEDSGKELILIGHKNHPEVKGIRGRVNNPIVLVQTLQNVRDLKVKNPDNLSYVTQTTLSTDDTREIITALKLRFPNITGPNLKDICYATQNRQNAVKKLTEIVDIVLIIGSKNSSNSNRLLDLCTARGKRAYLIDNYSYMDKSWLQGIEKIGITAGASAPDILVDELINHLKINVNTKVSVMSDGVTENVQFKIPHLV
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: PSD_CLOK5
Sequence: MIKYFNRKTKQYEIEQVAGEKYLKWTYCSPIGMKLLELIIKKKIFSKLYGYFCNSRYSKKNIYPFIKNFNINMDDYIEQTDNFKCFNDFFSRALKNNSRSIDRDEKVLISPGDGRLQVYENIDLNKIVQIKGFTYSLYNLINDIEIAKRFYKGTCLILRLCPTDYHRFHFIDYGICDFTHKIKGNYYSVNPIALRNISNIFCRNKREWSIFHSKNFGDILYVEVGATCVGSIVQTYFPGKHVSKGDEKGYFKFGGSTIILFFEQNKIRIHKDLLEQSNMGYETKVLMGESIGIKYQ
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type II sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: NUSB_STRPC
Sequence: MTNSFQNSRRDLRERAFQALFNIEMGAELLAASQFAYGYDKVTGEDAQVLELPIFLLSLVTGVNNHKEELDNLISTHLKKGWSLERLTLTDKTLLRLGLFEIKYFDETPDRVALNEIIEVAKKYSDETSAKFINGLLSQYVSEAPSANKS
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: TRPB_STRT2
Sequence: MTYQQPDAKGFYGKFGGQFVPETLMTAVIELDKAYREAKEDSSFQAELDDLLKNYVGRETPLYHAKRLTDHIGGAQIYLKREDLNHTGAHKINNALGQVLLAKRMGKKKIIAETGAGQHGVATATAAALFDMDCTIYVGEEDVKRQALNVFRMELLGAKVFSVTDGSRVLKDAVNAALRAWVAGIEDTHYIMGSALGPAPFPEIVRDFQSVIGREAKRQYAEISGGKLPDAVMACIGGGSNAIGMFYPFVNDKSVAMYGAEASGLGLDTEKHAATFAKGRPGILHGALMDVLQDAHGQIMEAFSISAGLDYPGVGPEHCYFNEIGRATYDSITDEEALEGFKLLSRLEGIIPALESSHAIALAQKVAAKMSPDQSLIVCLSGRGDKDVMQVKERFEAEAEGK
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: RECA_ALTMD
Sequence: MDDNKSKALTAAVGQIEKQFGKGAIMRLGDNQAMDIEAISTGSLTIDIALGIGGLPCGRVVEIYGPESSGKTTLTLQVIAEAQKNGKTCAFVDAEHALDPVYAEKLGVNIDELLVSQPDTGEQALEICDMLVRSGAVDVVIVDSVAALTPKAEIEGDMGDSHVGLQARLMSQALRKLTANIKRSNTLCIFINQIRMKIGVMFGNPETTTGGNALKFYSSVRLDIRRIGAVKEGDEVVGNETRVKVVKNKVAPPFKQAEFMIRYGEGISKEAELIDLGVKQKLVDKAGAWYSYKGDRIGQGKANVMKYLKEHPETANEIETKIRQELLLSKTVKAEEALPQGEDDVLPE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPNP_SHIB3
Sequence: MLQSNEYFSGKVKSIGFSSSSTGRASVGVMVEGEYTFSTAEPEEMTVISGALNVLLPDATDWQVYEAGSVFNVPGHSEFHLQVAEPTSYLCRYL
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: EFTS1_TRYCC
Sequence: MLCLTRLRANVNKVAFMEMVKDLRFRTEAPIAECGAALKETHGDVEKAMEVLRKKGAARAMKKRSRVTEHGSVVACVGGLFGAAVITVCSETDFAARSAQFQNTCARVKVALQRKIIDSKGDVLTNPTEAHRSLVEATAEDIRSSIAVLGENVTIKSVESLRLAPHVAEHISIGSYTHGSLDVPDVGRIAGVVAVSRLDPTKEVQASTLTDVARHFVASSGAEGNYAHQNFFGTEETVGQWLKRHGLCFSSSLVVDFGKEPITHTASQPRNAVKHPEG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts 1, mitochondrial, EF-Ts 1, EF-TsMt 1.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: DNLJ_BRUA2
Sequence: MSDISVEKLTELEAAAELERLARAIAHHDELYHAKDRPEISDAAYDALKRRNEAIEAHFPALVRDDSPSRRVGAAPALATFAPVVHARPMLSLDNAFSDEDVRDFVGSVYRFLGQLPDDSIAFTAEPKIDGLSMSIRYENGILVSGATRGDGTTGENVTANIRTIAEIPNRLPAGAPAVVEVRGEVYMAKSDFLTLNAQMEAEGKQTYVNPRNTAAGSLRQLDAKVTASRKLRFFAYAWGEMSDMPADTQLGMVEVFRQWGFPVNPLMKRFNSVDGLLAHYRAIGMERPTLDYDIDGVVYKVDRLDLQTRLGFRSRSPRWAIAHKFPAEQALTILRGIDIQVGRTGALTPVARLEPITVGGVVVTNATLHNEDYIKGIGQKGEPIREGRDIRIGDSVIVQRAGDVIPQIVDVVLEEGKKRGEPYQFPHVCPACGSHAVREEGEAVRRCTGGLICPAQAVERIRHFVSRNAFDIEGLGEKQVEFFFNAEDPALCIRSPADIFTLKKRQENSLTKLQNIEGFGATSVKKLYDAIDARREIALHRFLFGLGIRHVGEVNAKRLARAYLSYAAFEKAALEAVPPKEGDRTDKGSEAWQDMLAVEGIGSIVAEAVVDFYGEPHNREVLAALLAEVTPLDEEARVATGSPVEGKTVVFTGSLERMSRDEAKAMAERHGAKTAGSVSKKTDLVVAGPGAGSKLAKATELGIEVINEDDWFKLVGED
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: TCMO_CATRO
Sequence: MDLLLLEKTLLGLFAAIIVASIVSKLRGKKFKLPPGPIPVPVFGNWLQVGDDLNHRNLSDYAKKFGEIFLLRMGQRNLVVVSSPELAKEVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGEHWRKMRRIMTVPFFTNKVVQQYRYGWEEEAARVVEDVKKNPESATNGIVLRRRLQLMMYNNMYRIMFDRRFESEDDPLFVKLKALNGERSRLAQGFEYNYGDFIPILRPFLRGYLRICKEVKERRLQLFKDYFVDERKKFGSTKSMDNNSLKCAIDHILEAQQKGEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPEIQKKLRDELETVLGPGVQITEPDTYKLPYLQAVIKETLRLRMAIPLFLPHMNLHDAKLGGYDIPAESKILVNAWFLANNPEHWKKPEEFRPERFLEEESKVEANGNDFRYLPFGVGRRSCPGIILALPILGITIGRLVQNFELLPPPGKSKIDTSEKGGQFSLHILKHSTIVLKPRTF
What is the function of this protein?
Catalyzes the first oxidative step of the phenylpropanoid pathway in higher plants by transforming trans-cinnamate into p-coumarate (By similarity).  The compounds formed by this pathway are essential components for lignification, pollination, and defense against ultraviolet light, predators and pathogens (By similarity).
What are the official names of this protein?
Trans-cinnamate 4-monooxygenase, Cinnamic acid 4-hydroxylase, C4H, CA4H, Cytochrome P450 73, Cytochrome P450C4H.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: NDK_STAA2
Sequence: MERTFLMIKPDAVQRNLIGEVISRIERKGLKLVGGKLMQVPMELAETHYGEHQGKPFYNDLISFITSAPVFAMVVEGEDAVNVSRHIIGSTNPSEASPGSIRGDLGLTVGRNIIHGSDSLESAEREINLWFNENEITSYASPRDAWLYE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK33_DIOEL
Sequence: MAKGKDVRVRIILECASCVRNGINKELPGISRYITQKSRHNTPNRLELRKYCHYCRTHTIHGEIKK
What are the official names of this protein?
50S ribosomal protein L33, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.