PharMolix/UniProtQA huggingface dataset:
Protein: MURG_STAA9
Sequence: MTKIAFTGGGTVGHVSVNLSLIPTALSQGYEALYIGSKNGIEREMIESQLPEIKYYPISSGKLRRYISLENAKDVFKVLKGILDARKVLKKEKPDLLFSKGGFVSVPVVIAAKSLNIPTIIHESDLTPGLANKIALKFAKKIYTTFEETLNYLPKEKADFIGATIREDLKNGNAHNGYQLTGFNENKKVLLVMGGSLGSKKLNSIIRENLDALLQQYQVIHLTGKGLKDAQVKKSGYIQYEFVKEDLTDLLAITDTVISRAGSNAIYEFLTLRIPMLLVPLGLDQSRGDQIDNANHFADKGYAKTIDEEQLTAQILLQELNEMEQERTRIINNMKSYEQSYTKEALFDKMIKDALN
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GPRK2_DROME
Sequence: MELENIVANTVYLKAREGGSDSNKGKSKKWRKILQFPHISQCINLKDKLDISYGYVIDQQPIGRELFRLFCENKRPVYFRYITFLDEVVKYEIEYISNRIFIGHDIGRRFLDVEAQLELRNGSGGDALDAETQEELLLNSSNANPTETAETEHCNNTTANNCNNINNSNNSQHSSDINHKKLDTRNHNGDDATGNGSSHQDDGDESVKCQEGHDDAEKGGGGEGGGGGKCVPVGGYPDELVLDVLNDDLIAQVRNKLNSGGKDIFAQCVNAVKAFLAGEPFREFESSMYFHRYLQWKWLEAQPITYKTFRMYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGESMVLIEKQILQKINSPFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGGEPGFELERARFYAAEVACGLQHLHKQGIVYRDCKPENILLDDHGHVRISDLGLAVEIPEGEMVRGRVGTVGYMAPEVIDNEKYAFSPDWFSFGCLLYEMIEGQAPFRMRKEKVKREEVDRRVKEDPEKYSSKFNDEAKSMCQQLLAKSIKQRLGCRNGRMGGQDVMAHPFFHSTQLNWRRLEAGMLEPPFVPDPHAVYAKDVLDIEQFSTVKGVNIDESDTNFYTKFNTGSVSISWQNEMMETECFRELNVFGPEECPTPDLQINAAPEPDKAGCFPFRRKKKQPARTQPIPIPEHLLTTSHSVSSTTVES
What is the function of this protein?
Specifically phosphorylates the activated forms of G protein-coupled receptors (By similarity).  Required during oogenesis and embryogenesis; component of a signaling pathway that functions during egg chamber maturation.
What are the official names of this protein?
G protein-coupled receptor kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
What are the subcellular locations of this protein?
Membrane. Note=Associated with nurse cell and oocyte plasma membranes during much of oogenesis.
Protein: UDGB_MYCTU
Sequence: MHPKTGRAFRSPVEPGSGWPGDPATPQTPVAADAAQVSALAGGAGSICELNALISVCRACPRLVSWREEVAVVKRRAFADQPYWGRPVPGWGSKRPRLLILGLAPAAHGANRTGRMFTGDRSGDQLYAALHRAGLVNSPVSVDAADGLRANRIRITAPVRCAPPGNSPTPAERLTCSPWLNAEWRLVSDHIRAIVALGGFAWQVALRLAGASGTPKPRFGHGVVTELGAGVRLLGCYHPSQQNMFTGRLTPTMLDDIFREAKKLAGIE
What is the function of this protein?
DNA glycosylase with broad substrate specificity.  Can remove uracil from double-stranded DNA containing either a U/G, U/A, U/C or U/T base pair.  Can also excise ethenocytosine and hypoxanthine from double-stranded DNA.
What are the official names of this protein?
Type-5 uracil-DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.
Protein: Y173_BUCAI
Sequence: MNSLSNIDFSKLSLFESIIVASQAIREDFPSHSVLTELKNRIKEAESYISSENEPDRKLEKLLQLFYTQWNFGGASGVYKLSDTLWIDNVLKTRKGTAVSLGIIFLHIAQSLKLPLNPVVFPTQLILRADWINEKKWLINPFNGEILDQHTLEVWLKGNISPTAELYENDLYKSESITVIRKMLDTLKAALMEEKKMELALNVTNLLIKIDPNDPYEIRDRGLIYAQLECNHVALTDLIYFVEHCPEDPISEIIKIQIHSIEQKKTILH
What are the official names of this protein?
UPF0162 protein BU173.
What is the protein family that this protein belongs to?
Belongs to the UPF0162 family.
Protein: CBLN4_MOUSE
Sequence: MGSARRALSVVPAVLLILVLPVWAQNDTEPIVLEGKCLVVCDSNPATDSKGSSSSPLGISVRAANSKVAFSAVRSTNHEPSEMSNKTRIIYFDQILVNVGNFFTLESVFVAPRKGIYSFSFHVIKVYQSQTIQVNLMLNGKPVISAFAGDKDVTREAATNGVLLYLDKEDKVYLKLEKGNLLGGWQYSTFSGFLVFPL
What is the function of this protein?
Acts as a synaptic organizer in specific subsets of neurons in the brain (PubMed:29691328).  Essential for the formation and maintenance of inhibitory GABAergic synapses (PubMed:25534236).  Promotes the development of dendrite-targeting inhibitory GABAergic synapses made by somatostatin-positive interneurons (PubMed:30679375).  May contribute to the function of ventral medial habenula region of the brain implicated in the regulation of anxiety-related behaviors (PubMed:30287486).  May play a role in CBLN3 export from the endoplasmic reticulum and secretion (PubMed:17030622).
What are the official names of this protein?
Cerebellin-4, Cerebellin-like glycoprotein 1.
What are the subcellular locations of this protein?
Secreted. Synapse. Note=Detected at GABAergic synapses.
Protein: NAGZ_SALA4
Sequence: MGPVMLNVEGCELDAEEREILAHPLVGGLILFTRNYHDPEQLRELVRQIRAASRNHLVVAVDQEGGRVQRFREGFTRLPAAQSFFALHGLEEGGRLAQEAGWLMASEMIAMDIDISFAPVLDVGHISAAIGERSYHADPAKALAMATRFIDGMHDAGMKTTGKHFPGHGAVTADSHKETPCDPRPETDIRGKDMSVFRTLISENKLDAIMPAHVIYRAIDPRPASGSPYWLKTVLRQELGFDGVIFSDDLSMEGAAIMGSYAERAQASLDAGCDMILVCNNRKGAVSVLDNLSPIKAERVTRLYHKGSFSRRELMDSARWKTASAQLNQLHERWQEEKAGH
What is the function of this protein?
Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.
What are the official names of this protein?
Beta-hexosaminidase, Beta-N-acetylhexosaminidase, N-acetyl-beta-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APOA1_ICTTR
Sequence: MKAVVLTVAVLFLTGSQARHFWQQDEPQSSWDRIKDFATVYLDAVKDSGRDYVTQFETSALGKQLNLKLLDNWDSLSSTVSKVREQIGPVSQDFWDKLEKDTVSLRQEMNKDLEEVKRKVQPYLDEFQKRWQEDVERYRQQVEPLSKELREGARQKLLELHEKLSPLGQEMRDRARTHVDALRTHLAPYSDELRQRLAARLEALKEGSSFAEYQAKATEHLSALGEKAKPALEDLRQGLLPVLESLKLSFWSAVDEATKKLNTQ
What is the function of this protein?
Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT).  As part of the SPAP complex, activates spermatozoa motility.
What are the official names of this protein?
Apolipoprotein A-I, Apo-AI, ApoA-I.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted.
Protein: UXUA_SALTI
Sequence: MKQTWRWYGPNDPVTLSDVRQAGATGVVTALHHIPNGEIWSVDEIQKRKAIVEEAGLEWSVVESVPIHEDIKTHTGQYDLWIKNYQQTLRNLAQCGIYTVCYNFMPVLDWTRTDLEYVLPDGSKALRFDQIEFAAFELHILKRPGAEADYTAEEIAQAERRFATMSEEDKARLTRNIIAGLPGAEEGYTLDQFRQHLATYKDIDKAKLREHFAYFLKAIIPVADEVGVRMAVHPDDPPRPILGLPRIVSTIEDMQWMVETVNSMANGFTMCTGSYGVRADNDLVDMIKQFGPRIYFTHLRSTLREENPKTFHEAAHLHGDVDMYEVVKAIVEEEHRRKAEGSDDLIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAEVRGVELAIQRAFFSK
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.
What are the official names of this protein?
Mannonate dehydratase, D-mannonate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the mannonate dehydratase family.
Protein: UXAC_YERP3
Sequence: MSQFLTEDFLLDTEFARRLYHDYAKDQPIFDYHCHLPPEQIAENYRFKNMYDIWLKGDHYKWRAMRTNGVAERLCTGDASDREKFDAWAATVPHTIGNPLYHWTHLELRRPFGITGKLLSPATSEEIWQRGNELLAQDPFSARGIMQQMNVKMVGTTDDPIDDLRHHKAIAADGSFNIKVLPSWRPDKAFNIEAAGFNDYMQRLEAAADTSISRFADLCVALNKRMDHFAAHGCKVSDHALDVVVYGEADETTLDAILARRLAGNQPSTEEIAQFKTAVLLFLSGEYHRREWVQQYHIGALRNNNSRMFNLVGPDIGFDSINDQPLAQPLSRLLDAQGLRNALPKTILYCLNPRDNEVIGTMVGNFQGEGEAGKMQFGSGWWFNDQKDGMQRQMTQLAQLGLLSRFVGMLTDSRSFLSYTRHEYFRRILCQMIGRWVADGEAPADIALLGAMVKNICFDNAQQYFAIEL
What are the official names of this protein?
Uronate isomerase, Glucuronate isomerase, Uronic isomerase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.
Protein: BUD32_YARLI
Sequence: MITLPEQLEKLSKQENLIAQGAESLVYSAQHPYLPQQECIVKYRPKKPYRLPELDAQLSKHRTLAEARVLQKLALGDVEVPHLVFIDAKNGLIYMEKIEGLSVKQWIWNEEGDTEGGAQEAGDKSRSLPDGDVSSLKDTLVLVGQEIGKLHKSDIVHGDLTTSNVMLRDGKPVIIDFGLASVSTLAEDKAVDLYVMERAVLSTHPVHSQQYCDWLFEGYLAVVGKSQKEVMRKLEDVRQRGRKRSMLG
What is the function of this protein?
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.  BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1.  The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation.  The complex is required for efficient recruitment of transcriptional coactivators.
What are the official names of this protein?
EKC/KEOPS complex subunit BUD32, Atypical serine/threonine protein kinase BUD32.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. BUD32 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Chromosome, telomere.
Protein: Y208_STRZJ
Sequence: MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYVLLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE
What are the official names of this protein?
UPF0473 protein SPJ_0208.
What is the protein family that this protein belongs to?
Belongs to the UPF0473 family.
Protein: PG021_CWPXB
Sequence: MEFDPTKINISSIDHVTILQYIDEPNDIRLTVCIIQNINNITYYINITKINPHLANQFRTWKKRIAGRDYMTNLSRDTGIQQSKLTETIRNCQKNRNIYGLYIHYNLVINVVIDWITDVIVQSILRGLVNWYIANNNYTPNTPNNTTTISELDIIKILDKYEEVYRVSKEKECGICYEVVYSKRLENDRYFGLLDSCNHIFCITCINIWHRTRRETGASDNCPICRTRFRNITMSKFYKLVN
What is the function of this protein?
RING-finger E3 ubiquitin ligase which catalyzes the formation of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.  Plays an important role in virulence by acting as an anti-apoptotic factor.
What are the official names of this protein?
host range factor p28, E3 ubiquitin-protein ligase p28, Protein CPXV023.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG021 family.
Protein: SGF11_SCHPO
Sequence: MQPASLAGISCTIFENLLKDYTHELTQTVHKNAKLSLQKCPACNKHCRQYCTKPGYDIYGNSVQTPSNVPYYSCLMCKREIAASRYAAHLEKCKGRSLSNATSYSTLFEDDNADEED
What is the function of this protein?
Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA.  At the promoters, SAGA is required for recruitment of the basal transcription machinery.  It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination.  SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac).  SAGA interacts with DNA via upstream activating sequences (UASs).  Involved in transcriptional regulation of a subset of SAGA-regulated genes.  Within the SAGA complex, participates in a subcomplex, that specifically deubiquitinates histones H2B.
What are the official names of this protein?
SAGA-associated factor 11.
What is the protein family that this protein belongs to?
Belongs to the SGF11 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: AROB_BORBR
Sequence: MDVVEVATPGGSYPIHIGPGRLDALDASIPADATAIAVVTNPTVAGLYGARVEAALARTGKRVLRIELPDGEAHKDWQTLNLIFDALLENRLDRRAVLVALGGGVIGDMTGFAAAVYMRGIRFVQVPTTLLAQVDSSVGGKTAVNHPLGKNMIGAFYQPVAVEIDTEVLGTLPAREVSAGLAEVIKYGLILDAGFWQWCEDNVGALRALEPRALAYAIRRSCELKAQVVGQDERESGLRAILNLGHTFGHAIESGLGYGEWLHGEAVGCGMVQAAELSTLAAGFPAADVQRVRDLVREIGCPTVAPDLGAERWLALMQVDKKTEGGEIRFVLMPRIGQALSRAAPEADVRTALERTTR
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AAEX_SALDC
Sequence: MSLFPVIVVFGLSFPPIFFELLLSLAIFWLVRRMLVPTGIYDFVWHPALFNTALYCCLFYLISRLFV
What are the official names of this protein?
Protein AaeX.
What is the protein family that this protein belongs to?
Belongs to the AaeX family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPOB_NEIG2
Sequence: MNYSFTEKKRIRKSFAKRENVLEVPFLLATQIDSYAKFLQLENAFDKRTDDGLQAAFNSIFPIVSHNGYARLEFVYYTLGEPLFDIPECQLRGITYAAPLRARIRLVILDKEASKPTVKEVRENEVYMGEIPLMTPSGSFVINGTERVIVSQLHRSPGVFFEHDKGKTHSSGKLLFSARIIPYRGSWLDFEFDPKDLLYFRIDRRRKMPVTILLKALGYNNEQILDIFYDKETFYLSSNGVQTDLVAGRLKGETAKVDILDKEGNVLVAKGKRITAKNIRDITNAGLTRLDVEQESLLGKALAADLIDSETGEVLASANDEITEELLAKFDINGVKEITTLYINELDQGAYISNTLRTDETAGRQAARVAIYRMMRPGEPPTEEAVEQLFNRLFFSEDSYDLSRVGRMKFNTRTYEQKLSEAQQNSWYGRLLNETFAGAADKGGYVLSVEDIVASIATLVELRNGHGEVDDIDHLGNRRVRSVGELTENQFRSGLARVERAVKERLNQAESENLMPHDLINAKPVSAAIKEFFGSSQLSQFMDQTNPLSEVTHKRRVSALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYARTNDYGFLETPYRRVIDGKVTEEIDYLSAIEEGRYVIAQANADLDSDGNLIGDLVTCREKGETIMATPDRVQYMDVATGQVVSVAASLIPFLEHDDANRALMGANMQRQAVPCLRPEKPMVGTGIERSVAVDSATAIVARRGGVVEYVDANRVVIRVHDDEATAGEVGVDIYNLVKFTRSNQSTNINQRPAVKAGDVLQRGDLVADGASTDLGELALGQNMTIAFMPWNGYNYEDSILISEKVAADDRYTSIHIEELNVVARDTKLGAEDITRDIPNLSERMQNRLDESGIVYIGAEVEAGDVLVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRMPTGMSGTVIDVQVFTREGIQRDKRAQSIIDSELKRYRLDLNDQLRIFDNDAFDRIERMIVGQKANGGPMKLAKGSEITTEYLAGLPSRHDWFDIRLTDEDLAKQLELIKLSLQQKREEADELYEIKKKKLTQGDELQPGVQKMVKVFIAIKRRLQAGDKMAGRHGNKGVVSRILPVEDMPYMADGRPVDIVLNPLGVPSRMNIGQILEVHLGWAAKGIGERIDRMLKERRKAGELREFLNKLYNGSGKKEDLDSLTDEEIIELASNLRKGASFASPVFDGAKESEIREMLNLAYPSEDPEVEKLGFNDSKTQITLYDGRSGEAFDRKVTVGVMHYLKLHHLVDEKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYENIVKGEHKIDAGMPESFNVLVKEIRSLGLDIDLERY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: SSRP_ACIBT
Sequence: MAKATVVKKHNGGTIAQNKRARHDYFIEEKFEAGMSLLGWEVKSLRAGRMSLTESYVIFKNGEAFLFGAQIQPLLSASTHIVPEATRTRKLLLSRRELEKLMGAVNQKGYSCVPLACYWKGHLVKLEIALVKGKQLHDKRATEKERDWQRDKARIFHK
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: AMPA_GLOVI
Sequence: MEFEAVRISPGKYRGDALLVGLFQDGPEPALALAALDAAVAAVVLEVISEEEFKPKSRQKLTVRVGGDTGLRKVVLVGLGEQAKYKPESLRQCIGEGARTLKAIKATTAGVWVPPLGEGGEEATVEALVEAIRLALHEDRRFRSKKSDSEENGNSNNGGENKLTKVSLVVAGEGDYAAAVRRGNILAEGTIFARELVSAPANYVTSVTLAEQATAIAEANGLECEILEKEDCERLGMGAYLGVAQGTDLPPKFIHLTYKPAHSAPRKRIAIIGKGITFDSGGLSIKPAKGMELMKVDMGGAAAALGAAKVLGQLKPDIEVHFIVAATENMVSGHAIHPGDILTASNGKTIEVDNTDAEGRLTLADALVFSEKLGVDAIVDLATLTGACVVALGNDIAGLLTENEELARQIRAAGEASGEKFWQLPMEESYFEGMKSVVADMRNTGSREGGTITAALFLKQFVEKTPWVHLDIAGPVWTEKQKGYTNRGGTGFGVRTLVRFVLAQ
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBIF_METJA
Sequence: MDNNRKVIIVGAGPGDPELITIKGKKAIEEADVIIYAGSLVNEKLLEYNKKNAEIYNSANMNLEEIIDVMVKAVNQGKKVVRLHTGDPSIYGAIKEQIDELSKYGIDVEIIPGVSSLFAATASLKVELTLPEVSQTVIITRPEGRTPMPEKEKLRDLAKHQSTMAIFLGVSMIDKVVKELIEGGYREETPVAVVYHASWDDEKIVRGTLKDIAEKVKKEGIKKTALIIVGEVLNPKYYAYSKLYDKNFEHEYRKSHKKF
What is the function of this protein?
Catalyzes the methylation of C-11 in cobalt-precorrin-4 to form cobalt-precorrin-5A.
What are the official names of this protein?
Cobalt-precorrin-4 C(11)-methyltransferase, Cobalt-precorrin-3 methylase.
What is the protein family that this protein belongs to?
Belongs to the precorrin methyltransferase family.
Protein: FGD_MYCTU
Sequence: MAELKLGYKASAEQFAPRELVELAVAAEAHGMDSATVSDHFQPWRHQGGHAPFSLSWMTAVGERTNRLLLGTSVLTPTFRYNPAVIAQAFATMGCLYPNRVFLGVGTGEALNEIATGYEGAWPEFKERFARLRESVGLMRQLWSGDRVDFDGDYYRLKGASIYDVPDGGVPVYIAAGGPAVAKYAGRAGDGFICTSGKGEELYTEKLMPAVREGAAAADRSVDGIDKMIEIKISYDPDPELALNNTRFWAPLSLTAEQKHSIDDPIEMEKAADALPIEQIAKRWIVASDPDEAVEKVGQYVTWGLNHLVFHAPGHDQRRFLELFQSDLAPRLRRLG
What is the function of this protein?
Is essential for the bioreductive activation of the bicyclic 4-nitroimidazole prodrug PA-824 (a nitroimidazo-oxazine) developed for anti-tuberculosis therapy against both replicating and persistent bacteria.  It does not interact directly with PA-824 but, rather, provides reduced F420 to the deazaflavin-dependent nitroreductase Ddn, which in turn activates PA-824.
What are the official names of this protein?
F420-dependent glucose-6-phosphate dehydrogenase, FGD, FGD1, G6PD.
What is the protein family that this protein belongs to?
Belongs to the F420-dependent glucose-6-phosphate dehydrogenase family.
Protein: ASPH2_DANRE
Sequence: MEWSLERMREWVAGGMQSVRECESSALGTALCLALLFIWYCYRVGCEHTSPSLRGGFSPEPRVGAVPGVLASELSSRGGSSKLRQIGGVGGGGVSDEELNGFAYCQSSECFRCTKPGEGLNQRLYHSLQEYAKRYTWAGMGRVHKGVREQGRYLLCSRPSIQKPEVFFLPDLPSAPFFSREAQKHDVELLERSFPALLAEFESVYRLPSSRTGSSLPPGWKANSTPRGQWWTFYLVNQGTPMVLNARRCPRTWRVLGQLRTFIANNVFGNACFSVLSPGSTITEHYGPTNVRLRCHLGLKVPSGCELVVGGEPQCWSEGSCLLFDDSFLHTAFHDGSAEDGPRAVFMVDLWHPNVAAAERQALDYIFTPGR
What are the official names of this protein?
Aspartate beta-hydroxylase domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the aspartyl/asparaginyl beta-hydroxylase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: RL3_ASPFU
Sequence: MSHRKYEAPRHGSLAFLPRKRAARHRGKVKSFPKDDPKKPVHLTASMGYKAGMTTVVRDLDRPGAKMHKKEIVEAVTIIETPPLVAVGVVGYIETPRGLRSLTTVWAEHLSDEVKRRFYKNWYKSKKKAFTKYAKKHAEENGASITRELERIKKYCTVVRVLAHTQIRKTPLKQKKAHLMEIQVNGGSVADKVDFARNLFEKPIEIDSIFEKDEMIDVIAVTKGHGFQGVTSRWGTKKLPRKTHKGLRKVACIGAWHPSHVQWTVARAGQMGYHHRTSCNHKVFRIGKGSDEGNASTDFDISKKQITPMGGFVRYGEVKNDYIMVKGSVPGVKKRVMTLRKTLYPQTSRRATEKVELKWIDTSSKFGHGAFQTPEEKRAFMGTLKKDLVTSA
What is the function of this protein?
The L3 protein is a component of the large subunit of cytoplasmic ribosomes.
What are the official names of this protein?
60S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTFA_SHIF8
Sequence: MIKWPWKVQESAHQTALPWQEALSIPLLTCLTEQEQSKLVALAERFLQQKRLVPLQGFELNSLRSCRIALLFCLPVLELGLEWLDGFHEVLIYPAPFVVDDEWEDDIGLVHNQRIVQSGQSWQQGPIVLNWLDIQDSFDASGFNLIIHEVAHKLDTRNGDRASGVPFISLREVAGWEHDLHAAMNNIQEEIELVGENAASIDAYAASDPAECFAVLSEYFFSAPELFAPRFPSLWQRFCQFYQQDPLQRLHHANDTDSFSATNVH
What is the function of this protein?
Involved in the regulation of ptsG expression by binding and inactivating Mlc.
What are the official names of this protein?
Protein MtfA, Mlc titration factor A.
What is the protein family that this protein belongs to?
Belongs to the MtfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1708_STAA2
Sequence: MENFDKTMKFDYEELPTQDVRDVLNNVYRTLDERGYNAVNQIVGYLLSGDPAYIPRQNEARNQIRHIDRDVIMEELVSYYLKEQNK
What are the official names of this protein?
UPF0297 protein SaurJH1_1708.
What is the protein family that this protein belongs to?
Belongs to the UPF0297 family.
Protein: AROB_LEPIN
Sequence: MSLIETVPVNTEHKSVPVHLHSNLSGLSEEIAKLPGVTSVFLITEKSIHSIYSKYLERELSSLPIKTIYIKGGEKSKHINRTGEVYNQLIEYGADRKSLILAFGGGVVGDFAGFIASTYLRGIRFVQIPTTLLACVDSSVGGKVAVNADFGKNMIGSFYQPEFVFAPLSVLSTLPDREWKCGQAEIIKHSLLSGGEYWEKVKTHSFKDLNVDSTILPYLIAESVRFKANVVSSDEKETGLRKILNLGHTTAHAIESVTKYKKYSHGEAVAIGLVTALLLSEQHSELDPVTTKETIESLKNYGLPFQTKLKSKQLAKHMLHDKKNVGGSIRFVLLKSPGSPIFDIPINSEDIILAIHKQKGI
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSPA_STAHJ
Sequence: MKKKYYITISLIVAIAILIIDQVTKRIIATTMNIGDSYEVIPNFLNITSHRNNGAAWGILSGKMGFFYIITIVILIVLVLFYIKEAKYNLFMQVAISLLFAGALGNFIDRLVNGEVVDFVDTNIFGYDFPIFNVADSSLTIGVLFIIIALLKDANSKE
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.