PharMolix/UniProtQA huggingface dataset:
Protein: RDRP_ACLSA
Sequence: MAFSYRTPQEELLSRLPQSQQEAISGFQYERFQKEEEKKVENFSFYLPEKTREWFTKSGVYLSPFAYVNHSHPGCKTLENHLLFNVVASYISKYSYVACLSIKSNKMSKMERLGSNSVKTYDILNRLVTAKDKARYGPLARPERSPCPKKTNIFIHDEIHYWSRDQLETFLQVHRPKNLWATLVFPPEILAGYKSSVLPFLYQFEIHGKDLVYMPDGVRSESYTQPLENGFLLSSSSILVRNKATGVEIRYQVSLVYSLGSHHLFHIYPTEDLMKEEVRRFGPYDLFDVGSLFVKPVRVPIQDFPLSVFKKIFIYLSSLKKPDVQSAVAKLRQLSDADISIESVFMVQEFASRVEKNGVGSWSCSFWECMKDWFFDKLPYREVLEKIGLANDFTRRLMKIKPLAFDIHTTDRPLTVRMVIDQIWGERQSSCDDVPNIIFYGRKEWLEHGLLPKVKKGLAKLVPGRETGGSDYPEEIYSDLLSSTSIWRSYDENLRHRKASPIVILKSEKAYSEAPGFSSNCISLCSTPFGEVIERTPFEVERERKKRELSFGCLDFHIRKMKVKDASELSIKLDEQNKEGLRRQKRKEKAKKTRMIPVHLLELGSDQKEKNLGQEASKGKGIEQEERRKSDEAKFDSGPSGVCSIKAENPVDAQHIAEPVPCLKLNDLIGKEKICSSGLIKTVGNDYLTLARQIEDMPLAQLKNRKAAYFCIDYPMVYFHDKISYPTFEATGEIKQIIMRARDKWGANFNSALIQVYNDGCRLPLHSDNEECYDDDEILTINVVGDAKFHTTCHGEIIDLRQGDEILMPGGYQKMNKHAVEVASEGRTSVTLRVHKRDFSFESKLRFIKGKFDCLFVSIAEIIHKKPEEVMMFIPHIVDRCVSNRGCSLDDARAICEKYEIKIECEGDCGLVECGTIGLSVGRMLLRGNHFTVASVRRSSMDSLANSSKELKSNGVLDHVMFNFHKRLRSVEPDLTVEEIKVDSSRAGKLLKSLMDGMTGIVSHNSTHEGWRMIKGINSTSEMRSFMSMIKGKSEETRGDLFDRVQELNFMKVKIYGIFGFAGSGKSHAIQNLIQTEFKGSQGVMVICPRRFLAKDWSEKGVDEKDIKTFESALKSDVKGKRLFILDEISLLPKGFTDLLMLKMHMEGILKKSTIVCIGDPLQAGYFCPKDDNYLSREGEIKRLFKDGVNYKWYSYRINKFIAKKLAIETMNDFIGIDEQNLIYKDMPSAHHFMENKGNHIEVILVPSMIEKELYSNYGNVMTFGESQGLTFNCGVIVLSEEAKLCSDAHIMVAITRFRRGFCFALGSKGSKEDYMRSMKSGLLQRMCSGIGASKEFILGSSSVKLILSEKDVSKGAGVDEMDREARLEGDVWLKSMIYLGKRYHIVEPLGQVIKLTENAIKCHIPVCSSQTLGPELDNIQAREFREFKGKNGWSNQFREEAGPNWKHPYRVNQAMSYEAIYPRHRMDDDLTFLAAIKKRLRFDNVANNYAKFKAAESRGKYLAKVFLRHVPIKCGRDQRLLDQCRQEFEETKLSKSAATIGAHSQRSDSDWPLDKIFLFMKSQLCTKFEKRFTEAKAGQTLACFPHKILVEFSPWCRYTEKVLTANLPDNYYIHQRKNFSELEDFAKRFSNGSMCVESDYTAFDVSQDHTILAFEVELLKHFGWDDKVLQSYIKMKCTLGCRLGGFAIMRFTGEFSTFLFNTLANMVFTFCRYEVPDGTPICFAGDDMCALRNLREIDTHECILSKLSLKAKVNRTKVPMFCGWRLCFDGLIKEPCLIYERLQVAIENGRLMDVIDSYFLEFSFAYKLGERLYSHLEIEQLNYHQVLTRFFIRNKHLLRGDSRHNISELEWLSDEDSDDDKGSQIEDRRRGYSNCWGEKLQNLF
What is the function of this protein?
Involved in viral RNA replication.
What are the official names of this protein?
RNA-directed RNA polymerase, 216.5 kDa protein, ORF1 protein, RNA replicase.
Protein: ALBA_METST
Sequence: MAEENIVYIGNKPVMNYVLAVVTQMNSGVTEVILKARGRAISRAVDVAEIVRNRFISDVDVKSIDISTEEIVGNEGTSSNVSAIEIRLSK
What is the function of this protein?
Binds double-stranded DNA tightly but without sequence specificity.  It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture.  However, it does not significantly compact DNA.  Binds rRNA and mRNA in vivo.  May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.
What are the official names of this protein?
DNA/RNA-binding protein Alba.
What is the protein family that this protein belongs to?
Belongs to the histone-like Alba family.
What are the subcellular locations of this protein?
Cytoplasm. Chromosome.
Protein: RS19_BURCJ
Sequence: MARSVKKGPFCDAHLLKKVEAAAASRDKKPIKTWSRRSTILPDFIGLTIAVHNGRQHVPVYISENMVGHKLGEFALTRTFKGHAADKKAKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: PPNP_VIBC1
Sequence: MSIKENSYFAGGVKSLGFNQQGQDVSVGVMLPGEYTFGTQAPERMSVVKGALIVKKAGEVDWVTYNTGEFFEVEGSSSFELQVKDATAYLCEYL
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: MOAC_SALRD
Sequence: MADPSTLTHPDPEGGVRMMDASQKSDSARTAVAAGRVHLGEEAFRRVREHDIEKGDVLTTAQIAGIMGAKQTDKLIPLCHDATINGVEVDFTFNEDEQAIDVRAFTKSFGVTGVEMEALTAVSVASLTIYDMCKSVTKDIRIGDVHLRAKTGGQSGNWKSKSEDTSPAES
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: NU4LC_ANGEV
Sequence: MIENALILGAYLFCIGFYGLITSRNMIRALMCLELIFNAVNINFVTFSNYFDTQERKGEIFSISVIAIAAAEAAIGLSIILIIYRNRKSTRIDQFNLLKW
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic, NAD(P)H dehydrogenase subunit 4L, NADH-plastoquinone oxidoreductase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RIMM_PHOLL
Sequence: MVTMSKQTCIELPVNPIVLGKLGSTYGIRGWLRVFSSTEHAEDIFAYQPWFIQRAGRWQHIELEAWKHHNQDMIIKIKGIDDLDAANSLTNCEIIVDSEQLPELDTGDYYWKDLIGCQVISTAGYNLGTVNDMMETGSNDVMVVKANLKDAFGVKERLIPFLDGQVIKKVDLATKTIEVDWDPGF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUED_ARCFU
Sequence: MEEEMIIGISTSFSAAHSIPGHKKCGKVHGHNFKVEVEISGKVKENGMVMDFFDLKRIVNEVVAKFDHTLLNEQIEIPTSENICLRIFSELAEKGLNVRRVRVAENEDKWAEIRR
What is the function of this protein?
Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde.
What are the official names of this protein?
Putative 6-carboxy-5,6,7,8-tetrahydropterin synthase, CPH4 synthase, Archaeosine biosynthesis protein QueD.
What is the protein family that this protein belongs to?
Belongs to the PTPS family. QueD subfamily.
Protein: TM39A_BOVIN
Sequence: MPGGRRGPSRQQLSRSALPSLQTLVGGGCGNGTGLRNRNGSAIGLPVPPITALITPGPVRHCQIPDLPVDGSLLFEFLFFIYLLVALFIQYINIYKTVWWYPYNHPASCTSLNFHLIDYHLAAFITVMLARRLVWALISEATKAGASSMIHYMVLISARLVLLTLCGWVLCWTLVNLFRSHSVLNLLFLGYPFGVYVPLCCFHQDSRAHLLLTDFPYAVQHQAVEESASTVGGLARSKDFLSLLLESLKEQFNNATPIPTHSCPLSPDLIRNEVECLKADFNHRIKEVLFNSLFSAYYVAFLPLCFVKSTQYYDMRWSCEHLIMVWINAFVMLTTQLLPSKYCDLLHKSAAHLGKWQKLEHGSYSNAPQHIWSENTIWPQGVLVRHSRCLYRAVGPYNVAVPSDVSHARFYFLFHRPLRLLNLLILIEGSVVFYQLYSLLRSEKWNHTLSMALILFCNYYVLFKLLRDRIVLGRAYSYPLNSYELKAN
What is the function of this protein?
Regulates autophagy by controlling the spatial distribution and levels of the intracellular phosphatidylinositol 4-phosphate (PtdIns(4)P) pools (By similarity).  Modulates (PtdIns(4)P) levels by regulating the ER-to-Golgi trafficking of the phosphatidylinositide phosphatase SACM1L (By similarity).
What are the official names of this protein?
Transmembrane protein 39A.
What is the protein family that this protein belongs to?
Belongs to the TMEM39 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: FEN1_CANGA
Sequence: MGIKGLNSIITEHVPSAIRKSDIKAFFGRKVAIDASMSLYQFLIAVRQQDGGQLSTETGETTSHLMGMFYRTLRMIDNGIKPCYVFDGKPPVLKSHELDKRTSRREETEKKLAEATEEAEKMKHERRLVKVSKEHNDEAKKLLELMGIPYVNAPGEAEAQCAELAKKGKVYAAASEDMDTLCYRTPYLLRHLTFSEARKEPIHEINTEIVLQGLELTIDQFIDLGIMLGCDYCDSIKGVGPVTALKLMKEHGSLEKIVEYIESGEANNKWKVPENWPYKEARELFVKPDVIDANEIDLKWTPPKEDELIQYLCHEKKFSEERVRSGIKRLQKGLKSGVQGRLDGFFKVVPKTKEQLEAAAAKAKLAKKNAKGAKGKVTKRR
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: Y195_STRT2
Sequence: MNPMGRKWANIVAKKTAKDGANSKIYAKFGVEIYVAAKQGEPDPESNSALKFVLERAKQAQVPKHVIDKAIDKAKGNTDETFVEGRYEGFGPNGSMIIVDTLTSNVNRTAANVRTAFGKNGGNMGASGSVSYMFDKKGVIVFAGEDADAIFEQLLEADVDVEDVEAEDGTITVYTEPTDLHKALEALRANGQEEFQVTELEMIPQTEVTLEGEDLETFKGLIDALEADDDVQKVYHNVADM
What are the official names of this protein?
Probable transcriptional regulatory protein stu0195.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family. YeeN subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATK_CYRRA
Sequence: MEEFKRYLELDRSQQHDFIYPLIFQESIYALAHDHGLNRSLLLENEGYDNKSSLLIVKRLITHLITQMYQQNRFIFSANDSNQNHFLGHNTNLYSQIILEGFAVVVEIPFSLRLISSLEGKEIVKSHNLRSIHSIFPFLEDKISHLNYVLDILIPHSIHLEILVQTLRYWVKDASSLHLLRFFLHEYRNWNSLITPNKSSFSFSKRNQRLFLFLYNFHVCEYESIFVFLRNQSSHLRSISSGTFLERIYFYRKIEHFVFVEVFTKDFQTVLWLFKDPFLHYVRYQGKSLLAAKGASLLMNKWKYYFVNFWQCYFSMWSQPRRIHINPLSNHSLDFLGYLSSMRLNPSMVRSQMLENSVLLGNAIKKFDTTVPITPLIGSLSKAKFCNVLGHPLSKPAWADLSDSDIIDRFGCIYRNLSHYHSGSLKKKSLYQIKYILRLSCARTLARKHKSTVRAFLKRLGVELLEEFFTEEEQVFYLTFPKASSPSRGLYRIYRKRVWYLDIICINDLANHS
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: EAMB_ECOUT
Sequence: MTPTLLSAFWTYTLITAMTPGPNNILALSSATSHGFRQSTRVLAGMSLGFLIVMLLCAGISFSLAVIDPAAVHLLSWAGAAYIVWLAWKIATSPTKEDGLQTKPISFWASFALQFVNVKIILYGVTALSTFVLPQTQALSWVVGVSVLLAMIGTFGNVCWALAGHLFQRLFRQYGRQLNIVLALLLVYCAVRIFY
What is the function of this protein?
Exporter of O-acetylserine (OAS) and cysteine.
What are the official names of this protein?
Cysteine/O-acetylserine efflux protein.
What is the protein family that this protein belongs to?
Belongs to the Rht family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NEUL4_MOUSE
Sequence: MAAGSGGSGGSGAGPGPGPGPGGGGGPGSSGPGLGSGGGLGGGGELHPRTGRLVSLSACGRTARRQQPGQEFNHGLVLSREPLRDGRVFTVRIDRKVNSWSGSIEIGVTALDPSVLDFPSSATGLKGGSWVVSGCSVLRDGRSVLEEYGQDLDQLVEGDRVGVERTATGELRLWVNGRDCGVAATGLPARVWAVVDLYGKCTQITVLPSEPGFSPPTPVPTPPLEPLAPPEDSALLEQGTSVDEAFMVSPAQARPETFPNSLDSHNDFASMELSEVVSNAILSAYNGGLLNVSLSSPPAGDGLASSGPATSPILTSNDALLFHEKCGTLIKLSNNNKTAERRRPLDEFNNGVVMTNRPLRDNEMFEIRIDKLVDKWSGSIEIGVTTHNPNSLEYPATMTNLQSGTIMMSGCGILTNGKGTRREYCEFSLDELQEGDHIGLTRKSNSALHFFINGIDQGVATPLTPPVVYGVVDLYGMAVKVTIVHNNNHSDRLRRNNAILRALSPEGALRRAAPAAQAEPERLLFHPNCGQKAAITHEGRTALRPHATDDFNHGVVLSSRALRDGEVFQVRIDKMVDKWAGSIEIGVTTHNPAYLQLPSTMTNLRSGTWMMTGNGVMHNGTTILDEYGHNLDRLKAGDTVGVVRREDGTLHFFVNGMTQGPAAWNVPPGVYAVVDLYGQAAQATIVDDVEVPPVSEPLPEGNNQMSPSSPSSAAGGSDLRFHQLHGSNAVITNGGRTALRHNCRSEFNDAIVISNRALRDGELFEIVIQKMVDRWSGSIEAGVTAIRPEDLEFPNTMTDIDYDTWMLSGTAIMQDGNTMRNNYGCDLDALGTGARIGMMRTAKGDLHYFINGQDQGAACSGLPPGKEVYAVVDLYGQCVQVSITNATGPMDNSLATSNTATEKSFPLHSPVAGVAHRFHSMCGKNVTLEEDGTRAVRVAGYAHGLVFSTKELKAEEVFEVKVEELDEKWAGSLRLGLTTLAPEDMGPGAGSGPGLPPSLPELRTKTTWMVSSCEVRRDGHLQRMNYGRNLERLGVGSRVGIRRCADDTMHILVDGEDMGPAAAGIAKNVWAVLDLYGPVRSVAIVSSTRLEEPEGTQPPSPSSDTGSEVEEDDEVEEQGLRGQNQVGIVPTALEFLENHGKNILLSNGNRTATRVASYNQGIVVISQPLVPHMLVQVRIDFLNRQWTSSLVLGVITCPPERLNFPASACALKRAAWLLRGRGVFHNGLKICEKFGPNLDTCPEGTILGLRLDSSGGLHLHINGVDQGVAVPDVPQPCHALVDLYGQCEQVTIVSPDPGTASGKIAGTQGDMEKADMVDGIKESVCWGPPPAASPLKSCEYHALCSRFQELLLLPEDYFMPPPKRSLCYCESCRKLRGDEAHRRRGEPPREYALPFGWCRFNLRVNPHLEAGTLTKKWHMAYHGSSVAVVRRVLDRGELGAGTTSILSCRPLKGEPGVGFEEPGENCAPPREEQPPPVLLSPSLQYAGAEMLASKVQFRDPKSQRTHQAQVAFQVCVRPGSYTPGPPSAALRELPDQHFSPSELEWVTKEKGATLLYALLVRVE
What is the function of this protein?
Promotes CCP110 ubiquitination and proteasome-dependent degradation.  By counteracting accumulation of CP110, maintains normal centriolar homeostasis and preventing formation of ectopic microtubular organizing centers (By similarity).
What are the official names of this protein?
Neuralized-like protein 4.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole.
Protein: YB33_SCHPO
Sequence: MSAIDSCEHTVSWKLCEQKYNEATTLLSKLKKLLGNFKENCTSVVVDGHKKPRSESRKKYDAKKQHQSSHFATPVKGVESSEPTEKKKRNKEALWLRARQKKWKEIFELCQKITSLLGGTILIDVSFSMEKDVLTYLWMRVHYQVISFFKHRIYEASTQHDPELLSSLVTMHIQYLNSTIQFYTTLIAIIGELYHLQCLSPLTSFFTSCVTPKTILESPLRKQGSHNWKTSTNSQSRLAALFSSIFEDSCLEVDSVKRLLSGSPSSSSSPLKKDSSSNSLTYEPALTDHKPQYLVLCVYRSLIYIGDVHRYLAEVRSPNVPDYQVSRRYYVMAANVAPDYGVHFHQLGLIEVADARSSSRKSSSGQSSSLKGNVNVEDKRLIQALPAISFFFLSSISPNNVAASSAKTSLFIALKRCFGKTNDGSNPCLYHKESSAISLFLRLYAIAFSNTDADYIQDSGPLFKRVRFLLSESLKSGLFSESSLLQMTYCALAARVLAPFIGFSDSGEHGESYPNLKLATQTTTMFFEVLSDSVNSQLPLQALTSGVSSKKDGNFDDLVERRQYGSLSSNAVLMPMLLPLCVLTSSCLQNGDVWLTKDIRTGLSQIFNRLSFFLENTNQTAPDDSVLVRCSSKSIGLLFFFPLVKVCGVPRDTLQWLYFSNHYPFNEEGKGPQVDDSDALITIALDSLYVLLNMRAKSTPNSTSFSSPPTPHRSPFSGQAFTGMGLSNYSLMSSSSFPSAQSSPTSPFLSGTPSIANQSSSIASLQFGRMVDSLVGPVQPIPAQTTGCSVHSLQQRTFSNESPRAVDSGFSRTSTPFSESTSSYPLVSGNLSSCETHLNGSPQNGHLQGERVLFRPLRSPALNTFSTPATEPPEHLVLSELLKKMVNISNN
What are the official names of this protein?
Uncharacterized serine-rich protein C2F12.03c.
What are the subcellular locations of this protein?
Nucleus.
Protein: COQ7_PSYWF
Sequence: MAKNLSIIDRAIVGFDSSLRAIIPHSNQTARPLPVSSDALPQLSITESRHVAGLMRINHTGEVCAQGLYHGQAFTAKDDLVKQAMQHSADEEIDHLVWCETRLDELGSHPSVFTPVWYGLSFGLGAIAGIISDEFSLGFVAETEAQVSEHLQDHIDQLPEQDTRSKEILAQMNIEELEHREAALNHGGKALSAPVRISMRWMANRMKNLAYHL
What is the function of this protein?
Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
What are the official names of this protein?
3-demethoxyubiquinol 3-hydroxylase, DMQ hydroxylase, 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the COQ7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TPIS_BACC1
Sequence: MRKPIIAGNWKMNKTLSEAVSFVEEVKGQIPAASAVDAVVCSPALFLERLVAATEGTDLQVGAQNMHFEKNGAFTGEISPVALSDLKVGYVVLGHSERREMFAETDESVNKKTIAAFEHGLTPIVCCGETLEERESGKTFDLVAGQVTKALAGLTEEQVKATVIAYEPIWAIGTGKSSSSADANEVCAHIRKVVAEAVSPAAAEAVRIQYGGSVKPENIKEYMAQSDIDGALVGGASLEPASFLGLLEAVK
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_BRASO
Sequence: MALGKRLKKAREGVDRTKLYPLADAIKMIKERATSKFDETIEVAINLGVDPRHADQMVRGVVMLPNGTGRTLRVGVFARGAKAEEAKAAGADVVGAEDLVEKVQNGNIDFDRCIATPDMMPLVGRLGKVLGPRGMMPNPKIGTVTMDVTGAVKGAKGGSVEFRVEKAGIIQAGVGKASFTEDKLVENIKALADAVVKAKPAGAKGTYVQRVAVSSTMGPGVKVEPGTVLA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: DNAK_POLAQ
Sequence: MGKIIGIDLGTTNSCVSVVENNAPKVVENAEGGRTTPSIIAYVEDGEVLVGAPAKRQSVTNPKNTIYAVKRLMGRKFTDPEVQKDIGLMPYSIIAADNGDAWVEARDRKMAPQQVSAEILRKMKKTAEDYLGEEVTEAVITVPAYFNDSQRQATKDAGRIAGLDVKRIINEPTAAALAFGLDKQDKVDRKIAVYDLGGGTFDVSIIEIANVDGEKQFEVLSTNGDTFLGGEDFDQRIIDWIIAEFKKEQGVDLSKDVLALQRLKDAAEKAKIELSSAQQTEINLPYVTADASGPKHLNLKLTRAKLESLVEELINRTAGPCLTAIKDAGVNVSEIDDVILVGGQTRMPAVQDKVKEIFGKEPRKDVNPDEAVAVGAAIQGSVLSGDRKDVLLLDVTPLSLGIETLGGVMTKMIPKNTTIPTKHSQVYSTAEDNQPAVTIKCFQGEREMAAANKLLGEFNLEGIAPAQRGMPQIEVTFDIDANGILHVTAKDKTTGKENKITIKANSGLTEEEIQRMVKDAEANAAEDKKALELVTARNTADALAHSTKKALEEHGASLEASEKEAIEAALKELDEAIKGSDKEAIEAKTEALGKASQKLGEKVMAAEQAKSGGAAPGAAPGGAQQAAPDADVVDADFKEVDDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: ABI2_MOUSE
Sequence: MAELQMLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSPDKQRALEETKAYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSRTHKIIAPANLERPVRYIRKPIDYTILDDIGHGVKVSTQNMKMGGLPRTTPPTQKPPSPPMSGKGTLGRHSPYRTLEPVRPPVVPNDYVPSPTRNMAPSQQSPVRTASVNQRNRTYSSSGSSGGSHPSSRSSSRENSGSGSVGVPIAVPTPSPPSVFPGHPVQFYSMNRPASRHTPPTIGGSLPYRRPPSITSQTSLQNQMNGGPFYNQNPVSDTPPPPPPVEEPVFDESPPPPPPPEDYEEEEAAVVEYSDPYAEEDPPWAPRAYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESIMHYSE
What is the function of this protein?
Regulator of actin cytoskeleton dynamics underlying cell motility and adhesion.  Functions as a component of the WAVE complex, which activates actin nucleating machinery Arp2/3 to drive lamellipodia formation (By similarity).  Acts as regulator and substrate of nonreceptor tyrosine kinases ABL1 and ABL2 involved in processes linked to cell growth and differentiation.  Positively regulates ABL1-mediated phosphorylation of ENAH, which is required for proper polymerization of nucleated actin filaments at the leading edge (By similarity).  Contributes to the regulation of actin assembly at the tips of neuron projections.  In particular, controls dendritic spine morphogenesis and may promote dendritic spine specification toward large mushroom-type spines known as repositories of memory in the brain (PubMed:15572692).  In hippocampal neurons, may mediate actin-dependent BDNF-NTRK2 early endocytic trafficking that triggers dendrite outgrowth (PubMed:27605705).  Participates in ocular lens morphogenesis, likely by regulating lamellipodia-driven adherens junction formation at the epithelial cell-secondary lens fiber interface (PubMed:15572692).  Also required for nascent adherens junction assembly in epithelial cells (By similarity).
What are the official names of this protein?
Abl interactor 2, Abelson interactor 2, Abi-2, Abl-binding protein 3, AblBP3, Arg-binding protein 1, ArgBP1.
What is the protein family that this protein belongs to?
Belongs to the ABI family.
What are the subcellular locations of this protein?
Cell projection, lamellipodium. Cell projection, filopodium. Cytoplasm, cytoskeleton. Cell junction, adherens junction. Cell projection, dendritic spine. Note=Localized to the protruding lamellipodia and filopodia tips (By similarity). Present at nascent adherens junctions where it clusters adjacent to the tips of F-actin protrusions (By similarity).
Protein: QUEF_RUTMC
Sequence: MSYQPNKVLEVFDNPKIERDFIIQINMPEFTCLCPKTGQPDFATLHFAYIADKACIELKSLKMYIWLYRNEGAFHEAVTNQILDDLVQVSNPRFIRLKAIFNIRGGVYTTIITEHKQKNWTPKAKVDL
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_METJA
Sequence: MQRARIKLSSTDHKVLDEICRQIKEIAEKTGVDISGPIPLPTKVLRVVTRKSPDGEGSSTFDRWTMKIHKRLIDIDADERALRHIMKIRIPDNVQIEIQFK
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: THIE_PROM3
Sequence: MKSMPVAPIADLRVAQLIDANLDRAREGLRVVEDWCRFGLDREDLVVTLKDWRQRLGRHHHDSYKQARSTATDQGIGLSHPAQQERHEPWHVVAANCARVQEALRVLEEFARQPDPQLAASAAAIRYGLYDLEVTVLQANAGKKRRQQLQACHLCLITTSQSDLANNDLFRTVSAALVAGIDMVQYRNKEASDLQRLTQAKELASLCRKHGALFIVNDRIDLALAVDADGVHLGQDDLPTDVARGLIGSERLLGRSTQFLAQLQKAEAEGCDYLGVGPVNSTATKPERQPIGLAYVKEASKATQLPWFAIGGINISNLEAVRQAGAKRIAVIGAIMNSKDPAATSLQLLEALR
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: GSDMT_ACTHA
Sequence: MTKSVDDLARGDQAGDEQDPVHREQQTFGDNPLEVRDTDHYMHEYVGGFVDKWDDLIDWKKRYESEGSFFIDQLRARGVETVLDAAAGTGFHSVRLLEEGFETVSADGSPQMLAKAFSNGLAYNGHILRVVNADWRWLNRDVHGEYDAIICLGNSFTHLFSERDRRKTLAEFYAMLKHDGVLIIDQRNYDSILDTGFSSKHTYYYAGEDVSAEPDHIDDGLARFKYTFPDKSEFFLNMYPLRKDYMRRLMREVGFQRIDTYGDFQETYGEDEPDFYIHVAEKSYRTEDEFVDMYSNAVHTARDYYNSEDADNFYYHVWGGNDIHVGLYQTPQEDIATASERTVQRMAGKVDISPETRILDLGAGYGGAARYLARTYGCHVTCLNLSEVENQRNREITRAEGLEHLIEVTDGSFEDLPYQDNAFDVVWSQDSFLHSGDRSRVMEEVTRVLKPKGSVLFTDPMASDSAKKNELGPILDRLHLDSLGSPGFYRKELTRLGLQNIEFEDLSEYLPVHYGRVLEVLESRENELAGFIGEEYRAHMKTGLRNWVQAGNGGSLAWGIIHARA
What is the function of this protein?
Catalyzes the methylation of glycine, sarcosine and dimethylglycine to sarcosine, dimethylglycine and betaine, respectively, with S-adenosylmethionine (AdoMet) acting as the methyl donor (PubMed:10896953).  Shows low level of activity on glycine when expressed in E. coli (PubMed:10896953).
What are the official names of this protein?
Glycine/sarcosine/dimethylglycine N-methyltransferase, SDMT, Dimethylglycine N-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Glycine N-methyltransferase family.
Protein: TRPC_KORVE
Sequence: MSSTLQAILDDTRRDLAARKSAARTKEFEKRAAEHTPRGFRTALWERAQAGVAVIAELKKASPSKGLIRANFDVIALAKELEEAGAAALSVLTDVPHFQGSLENLERASQTVRIPCLRKDFILDPAQIVEARAYGADAILLIVAALTDLDLRNLRDEAKRYGLDVLCEVHDRDELKRAADLGFDLIGVNNRNLKTFRVDIENSLRFAEEFPPNALRVAESGIHSREDIDRLRDAAYSAFLIGESLMRADSPSATLRELIG
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.