PharMolix/UniProtQA huggingface dataset:
Protein: IF2_BACC7
Sequence: MSKIRVHEYAKKHNISSKDLMTKLKEMNIEVSNHMTMLDDEVVNKLDNEYQAEKPSVADEFEVEEKVVRSKKNSNKKKKKGKGNEDKRQENFAGRQQTQTVETPDKITFSGSLTVGDLAKKLSKEPSEIIKKLFMLGIMATINQDLDKDTIELIANDYGIEVEEEVIVSETEFETFIDEQDDEENLKERPAVVTIMGHVDHGKTTLLDSIRNSKVTAGEAGGITQHIGAYQVEVNDKKITFLDTPGHAAFTTMRARGAQVTDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKMDKPAANPDRVMQELTEYELVPEAWGGDTIFVPISAIQGEGIDNLLEMILLVSEVEEYKANPNRYATGTVIEAQLDKGKGTIATLLVQNGTLRVGDPIVVGTTFGRVRAMVSDIGRRVKVAGPSTPVEITGLNEVPQAGDRFMAFADEKKARQIGESRAQEALLAQRGEKSKLSLEDLFQQIQEGDVKEINLIVKADVQGSVEAMAASLRKIDVEGVKVKIIHTGVGAITESDIILASASNAIVIGFNVRPDVNAKRTAELENVDIRLHRIIYKVIEEIEAAMQGMLDPEFEEKVIGQAEVRQTFKVTKVGTIAGCYVTDGKITRDSGVRIIRDGVVIYEGQLDTLKRFKDDVKEVAQNYECGITIEKYNDLKEGDIIEAYIMEEVKR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_UREU1
Sequence: MLQPKRTKFRKPHKVSYEGKAKGNKQVDFGEFGLMALEGAWIDARQIESARIAISKRLLKTGKMWIRIFPHMSLTKKPLEVRMGSGKGSPEKWVAVVKAGTVMFEIANVSEELMREALRAAGNKLPIKVKIVKKGEAN
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: RS15_MESM1
Sequence: MVSNTKKLELIKSFGKNEKDSGSIEAQIAILTEDIESLKLHFEKNKKDLHSRRGFIAKINHRKKLLAYLRKNKFTSYASLIEKLNIRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: NADK1_PROMM
Sequence: MRLDLVWVIYRAGSHSAHREACCCVDELQALGVKVVMAMSGVTANPFPDLLASEAGLPDLAVVLGGDGTVLGAARHLAVHDVPILSFNVGGHLGFLTHERCLLDGGQLWQRLLQDNFALERRMMLQAAVDSRSPAERTARPTASLQDLNGTKALHWALNDFYMRPYRDDVSPTCTLELEIDGEVVDHYRGDGLILATPTGSTGYSMASGGPILHPGIDAIIVSPICPMSLSSRPVIVPPASRLVIGLLGENTRRVKLWKDGASGALLEPGQCCVVQRARHHALMVVLEQSPSYYRTLTHKLHWAGSLLNNQPSPS
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase 1, ATP-dependent NAD kinase 1.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECCB1_MYCS2
Sequence: MAGFRLTTKVQVSGWRFLLRRVEHAIVRRDTRMFDDPLQFYSRAVFAGVVVSVLICLGAALMAYFKPLGKQGSDQLLVDRTTNQLYVMLPGSNQLRPVYNLTSARLVLGNASNPVAVKSEELNRISKGQSIGIPGAPYATPTGTPASQWTLCDTVAKPDSSAPKVETSILIRTLAIDSGVGPIRADQGMLVSYEGANWLITEGGRHSIDLADRAVTSAVGIPVTAKPTPISQGLFNALPNRGPWQLPQIPAAGAPNSVGLPENLVIGSVFRTATESDPQHYVVLPDGVARVNNTTAAALRATNSYGLMQPPAVEASVVAKIPEQVYVSPLPDQPLDVLLRQDSPVLCWSWQREPGDQAPKTTVIAGRRLPLPANAIGTGIDQIGGDSTVYIEGGQFVRLQSPDPRVGESMYYIDPQGVRYGIANDDAAKNLGLAGPVNAPWQVVGLLVDGPVLSKEAALIEHDTLPADPNPRKVASGEG
What is the function of this protein?
An ATPase (shown for residues 72-479) (PubMed:26396239).  Part of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB (PubMed:15687187).  Plays a role in DNA conjugation, in both donor and recipient strains (PubMed:15314236).
What are the official names of this protein?
ESX-1 secretion system ATPase EccB1.
What is the protein family that this protein belongs to?
Belongs to the EccB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: Y811_METTH
Sequence: MKGSDALIMALRNMAATLGVYDLMEVRVFLERSCRFVQERYRAIYVDAYMSMVVDSVLDLKAGFSGTPEMDDARYSLRDALKRLDEINAPTIVGLTVLYRTYVKGEPLHPPGTPFPGGFEVEKKDGVHYCPVKDKQSDNPEALCDICIARQSPLP
What are the official names of this protein?
UPF0305 protein MTH_811.
What is the protein family that this protein belongs to?
Belongs to the UPF0305 family.
Protein: TASP1_MOUSE
Sequence: MIMEKGMNSGEGLPSRSSQASAAKVTVKELETQQPCKEKRGGFVLVHAGAGYHSESKAKEYKHVCKRACQKAIEKLQAGALATDAVAAALVELEDSPFTNAGIGSNLNLLGEIECDASIMDGKSLNFGAVGALSGIKNPVSVAHRLLCEGQKGKLSAGRIPPCFLVGEGAYRWAVDHGIPSCPPSTMTTRFSLAAFKRNKRKLELAERVETDFIQLKRRRQSSAKENDSGTLDTVGAVVVDHEGNVAAAVSSGGLALKHPGRVGQAALYGCGCWAENTGAQNPYSTAVSTSGCGEHLVRTILARECSHALQAEDAHQALLETMQNKFISSPFLACEDGVLGGVIVLRSCRCSSESDSSQDKQTLLVEFLWSHTTESMCVGYMSAQDGKAKTHISRLPPGAVAGQSVAIEGGVCRLESPVN
What is the function of this protein?
Protease responsible for KMT2A/MLL1 and KMT2D/MLL2 processing and activation (PubMed:16951254).  Through substrate activation, it controls the expression of HOXA genes, and the expression of key cell cycle regulators including CCNA1, CCNB1, CCNE1 and CDKN2A (PubMed:16951254).
What are the official names of this protein?
Threonine aspartase 1, Taspase-1.
What is the protein family that this protein belongs to?
Belongs to the Ntn-hydrolase family.
Protein: RL5_BACVZ
Sequence: MNRLKEKYNKEISPALMTKFNYDSVMQVPKIEKIVINMGVGDAVQNAKAIDSAVEELTFIAGQKPVVTRAKKSIAGFRLREGMPIGAKVTLRGERMYDFLDKLISVSLPRVRDFRGISKKSFDGRGNYTLGIKEQLIFPEIDYDKVTKVRGMDIVIVTTANSDEEARELLTQVGMPFQK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: ATPE_PRIM1
Sequence: MKTIHVSVVTPDGPVYESEVEMVSTRAQSGELGILHGHIPMVAPLQIGAVRLKKASSTELVAVSGGFLEVRPDKVTILAQAAETAEEIDVARAEEAKKRAEMRLDSKQDDVDVKRAEIALKRAVNRLDISQRKF
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GCS2_CUPNH
Sequence: MSLETFKHSEALTFGVELELQLVNRHDYDLAPFAPDLLRALKGAEHAGDIKPEISPSMIEISTGICHTYQQALEELTVMRDLMVAASRSLNLGIAGGGTHPFQQWADRTISDSPRYQYISELYGYLAKQFTVFGQHVHIGCPSADESLFLLHAIGRYVPHFVALAASSPYVQGVDTGFASARLNSVAAFPMSGRAPFLLTWDAFTAYFEKMRNTGVIESMKDFYWDIRPKPEFGTIEVRVMDTPLTVQRACDIAAYIQMLARYLLLSRPFMPQEDDYLVYTFNRFQACRFGLEGEYVHPNELTRMPIADHILSICDALVPHAEALGSLEALANIRALAERRDGDAEWLRQVDADARSQRETVRKACDRWAA
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: UBIA_PSEPW
Sequence: MYLQLLKSLNRVHPRAWDFIQLSRMDRPIGIYLLLWPTLTAVWIAGLGSPTLANVLIFGLGVVLMRAAGCCINDFADRKVDGHVKRTADRPLASGRVKPREALALFGILVAVSFLLVLCTNSKTVWLSFGAVALAFCYPFMKRYTYYPQVVLGAAYSWGIPMAFTAAGGELPASAWLLYIANLLWTVGYDTYYAMVDRDDDLKIGVKSTAILFGESDRMIILTLQMLSLGCLLLAGSRFELGGWFHLGLLGAALCFAWEYWSTRKLDRESCFKAFLHNHWAGLLVFMGVVLDYALR
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RSMG_EDWI9
Sequence: MYKQLDTLLAQAGISLTDQQKQRLLGYVSLLDKWNKAYNLTSVREPRDMLVRHIMDSIVVSPYLQGLRFIDVGTGPGLPGIPLAIVRPDANFTLLDSLGKRVRFLRQVQHELRLDNIEPVQSRVEAFVAEPPFDGVISRAFASLQDMVSWCHHLPAAHHGRFYALKGGVPQDELQSLPAGVSVDQLIRLQVPMLEGERHLVVLKSD
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUDC_ECOSE
Sequence: MDRIIEKLDHGWWVVSHEQKLWLPKGELPYGEAANFDLVGQRALQIGEWQGEPVWLVQQQRRHDMGSVRQVIDLDVGLFQLAGRGVQLAEFYRSHKYCGYCGHEMYPSKTEWAMLCSHCRERYYPQIAPCIIVAIRRDDSILLAQHTRHRNGVHTVLAGFVEVGETLEQAVAREVMEESGIKVKNLRYVTSQPWPFPQSLMTAFMAEYDSGDIVIDPKELLEANWYRYDDLPLLPPPGTVARRLIEDTVAMCRAEYE
What is the function of this protein?
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.  The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing.  Has preference for mRNAs with a 5'-end purine.  Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.
What are the official names of this protein?
NAD-capped RNA hydrolase NudC, DeNADding enzyme NudC, NADH pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudC subfamily.
Protein: PSBK_SPIOL
Sequence: MLNIFSLICLNSALYSSSFFFGKLPEAYAFLSPIVDFMPVIPLFFFLLAFVWQAAVSFR
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein K, PSII-K.
What is the protein family that this protein belongs to?
Belongs to the PsbK family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CH60_SYMTH
Sequence: MTAKQIIFDEAARRKLQAGVDALANTVKVTLGPRGRNVVLDKKFGAPAVANDGVTIAREIELEDPFENMGAQLVKEVATKTNDVAGDGTTTSTVLAQAIVKEGLKNVTGGANPMILKRGIEKAVQVAVEELRKQAIPVETNKAIAEVAAISANNDREIGELVAKAMDTVGKDGVITVEESKTLHTELETVEGMQFDRGYVSAYMVTDTEKMEAVLNEPYILITDKKISAVQDLLPILEKVVQRGKPLLIIAEDVEGEALATLVVNKLRGTLQVAAVKAPGFGDRRKAMLEDIAILTGGEVVSEELGRKLENATIEMLGQARQVRIEKEKTTIIDGAGSSEAIKNRVAAIKRQIEETTSDFDREKLQERLAKLAGGVAVIKVGAATEVELKEKKLRIEDALNATRAAVEEGIVAGGGVALLQTQKAIDELIKTLEGDEKVGAQIVRRAVEEPLRCIVENGGLEGSVVVEKVRTLPVGHGFDAMKEEYVDMVAAGIIDPVKVTRSALQNAASIAALILTTEALVTEKPEKKENNPAPNMDMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELA_NAUPA
Sequence: MNLFRQIPKVDKIEKALTHIPKKVLTPIIQKTLNEIREGIKNGKITQINEEDIVKTIEKRSEEILSPSIVNVINATGITVHTNLGRSLIDPEIFDYAKKRSTHYCNLEYDLEKGKRGDRYHHSAKILSHLFGSESALIVNNNAAAVFLILNTFAKDKEAIVSRGELVEIGGSFRVPEVMKASGAKLVEVGTTNKTKIQDYEDAITEDTAMLMKVHKSNYSIEGFSAEASLEEIIELAHKKNVLDYYDLGSAYIPKLPYSLTNYEPPISEIMKLNPSLVSFSGDKLFGSVQAGIILGKKDLIDKLKKNQILRMFRVDKITLSLIEATALAYIKEEYDKIPTLKSIFQTTEALKEKAKKLLSLTPGLKAEIKESHTYVGGGTMPNRKIPTVVVEIKGNAKKWEEDMRKHLVIGRIENEKFVLDMRSVQEDEIEKLAQIINSIITCEVKDA
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BCDO2_MACFA
Sequence: MVHPLPVFKRYTGNTHQKKAIFGQCRGLPCVAPLLTTVEEAPRGISARVWGHFPKWLNGSLLRIGPGKFEFGKDKYNHWFDGMALLHQFRMAKGTVTYRSKFLQSDTYKANSAKNRIVMSEFGTLATPDPCKNVFERFMSRFELPGKAAAMTDNTNVNYVRYKGDYYLCTETNFMNKVDIETLEKTEKVDWSKFIAVNGATAHPHYDPDGTAYNMGNSFGPFGFSYKVIRVPPEKVDLEETTHGAQVICSIAPTEKGKPSYYHSFGMTRNYIIFIEQPLKMNLWKIATSKIRGKAFSDGISWEPQCNTRFHVVDKHTGQLLPGRYYSKPFVAFHHINAFEDQGCVIIDLCCQDNGRILEVYQLQNLRKAGEELDQVYNSAGRSFPRRFVLPLNVSLNAPEGDNLSPLSYTSASAVKQADGTIWCSHENLHQEDLEKEGGIEFPQIYYGQFSGKKYRFFYGCGFRHLVGDSLIKVDVVNKTLKVWREDGFYPSEPVFVPVPGTNEEDGGVILSVVITPNQNESNFLLVLDAKNFEELGRAEVPVQMPYGFHGTFIPI
What is the function of this protein?
Broad specificity mitochondrial dioxygenase that mediates the asymmetric oxidative cleavage of carotenoids.  Cleaves carotenes (pure hydrocarbon carotenoids) such as all-trans-beta-carotene and lycopene as well as xanthophylls (oxygenated carotenoids) such as zeaxanthin, lutein and beta-cryptoxanthin at both the 9,10 and the 9',10' carbon-carbon double bond.  Through its function in carotenoids metabolism regulates oxidative stress and the production of important signaling molecules.
What are the official names of this protein?
Carotenoid-cleaving dioxygenase, mitochondrial, Beta-carotene dioxygenase 2.
What is the protein family that this protein belongs to?
Belongs to the carotenoid oxygenase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: Y2719_BACC4
Sequence: MNDLRYPIGQFTYKRPITEEMIDTWIQEIEDLPNELTKAIKDLDQKQLDTPYRVGGWTVRQVVHHVVDSHMNSYIRFKLALTEKNPTIKPYKEEKWAELPDSKLPVDVSLVMLDSLHKRWVNLLYSLEIEDLEKTFNHPETGETKLAVAIGLYAWHGRHHTAHITSLRKRLNW
What is the function of this protein?
Possible metal-dependent hydrolase.
What are the official names of this protein?
Putative metal-dependent hydrolase BCB4264_A2719.
What is the protein family that this protein belongs to?
Belongs to the metal hydrolase YfiT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURR_VIBCM
Sequence: MATIKDVARLAGVSTTTVSHVINKTRFVAETTQEKVMEAVKQLNYAPSAVARSLKCNTTRTIGMLVTQSTNLFFSEVIDGVESYCYRQGYTLILCNTGGIYEKQRDYIRMLAEKRVDGILVMCSDLTQELQDMLDAHKDIPKVVMDWGPETSHADKIIDNSEEGGYLATKYLTDRGHTEIACLSGHFVKAACQERIQGFRRAMAEAKLTVNEDWILEGNFECDTAVLAADKIIAMDKRPTAVFCFNDTMALGLMSRLQQKGIRIPEDMSVIGYDNIELAEYFSPPLTTVHQPKRRVGKNAFEILLERIKDKEHERRIFEMHPEIVERDTVKDLTKS
What is the function of this protein?
Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression.  PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.
What are the official names of this protein?
HTH-type transcriptional repressor PurR, Pur regulon repressor, Purine nucleotide synthesis repressor.
Protein: MADS1_ORYSI
Sequence: MGRGKVELKRIENKISRQVTFAKRRNGLLKKAYELSLLCDAEVALIIFSGRGRLFEFSSSSCMYKTLERYRSCNYNSQDAAAPENEINYQEYLKLKTRVEFLQTTQRNILGEDLGPLSMKELEQLENQIEVSLKQIRSRKNQALLDQLFDLKSKEQQLQDLNKDLRKKLQETSAENVLHMSWQDGGGHSGSSTVLADQPHHHQGLLHPHPDQGDHSLQIGYHHPHAHHHQAYMDHLSNEAADMVAHHPNEHIPSGWI
What is the function of this protein?
Probable transcription factor involved in the development of floral organs.  Required for the formation of inner floral organs (lodicules, stamens and carpels, or whorls 2, 3 and 4) and the lemma and palea (whorl 1), which are grass floral organs analogous to sepals.  May be involved in the control of flowering time.  Seems to act as transcriptional activator.  May act upstream of the auxin-responsive protein GH3. 8.
What are the official names of this protein?
MADS-box transcription factor 1, OsMADS1, Protein LEAFY HULL STERILE 1, Protein SEPALLATA-like.
What are the subcellular locations of this protein?
Nucleus.
Protein: BRM1L_HUMAN
Sequence: MPVHSRGDKKETNHHDEMEVDYAENEGSSSEDEDTESSSVSEDGDSSEMDDEDCERRRMECLDEMSNLEKQFTDLKDQLYKERLSQVDAKLQEVIAGKAPEYLEPLATLQENMQIRTKVAGIYRELCLESVKNKYECEIQASRQHCESEKLLLYDTVQSELEEKIRRLEEDRHSIDITSELWNDELQSRKKRKDPFSPDKKKPVVVSGPYIVYMLQDLDILEDWTTIRKAMATLGPHRVKTEPPVKLEKHLHSARSEEGRLYYDGEWYIRGQTICIDKKDECPTSAVITTINHDEVWFKRPDGSKSKLYISQLQKGKYSIKHS
What is the function of this protein?
Involved in the histone deacetylase (HDAC1)-dependent transcriptional repression activity.  When overexpressed in lung cancer cell line that lacks p53/TP53 expression, inhibits cell growth.
What are the official names of this protein?
Breast cancer metastasis-suppressor 1-like protein, BRMS1-homolog protein p40, BRMS1-like protein p40.
What is the protein family that this protein belongs to?
Belongs to the BRMS1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TGL5_SCHPO
Sequence: MSKNEIKLQMEYASSYETWLEAAEKLDVIEGKYQWREQKESDEYDYVLVESRLHELRRHRLSKNTRLLLGLLRNSVARDFANMDNSRLYNYAHSGTKKLIDEFIQEVLMCLTYLEETPDLSLDEKITEFSRLKLTTGNTALILSGGGTFGMTHIGVLQSLHEQGLVPKIICGSSAGAIVACAAAVRNKEEQEILLRQFHTGDLSVFTDPNAAPPSVIQSVKQYFTRGCVLDISHLERVMKLLIGDFTFQEAYDRSGYILNVTVSCGSLFEMPSLLNYITAPNVLVWSAVVATCSVPFLFKRATLWERDPLTREVSAFCVTDAPLWMDGSVDNDIPHAKLTELFHVNHFIVSQVNFHIVPFIMDPTSHNWVERCCKKAIDLAAQEVSLTFRLFAELGIFSVLFTKLQSVITQKYSGDITIIPRLNYREVNKVIKNPTPSFLLDAATRGKRGTWTKVPVTRNHCAIEILIAAAYTRLIKRSKSLK
What is the function of this protein?
Lipid particle-localized triacylglycerol (TAG) lipase.  The lipid droplet/particle is a lipid storage compartment which serves as a depot of energy and building blocks for membrane lipid biosynthesis.  Involved in the mobilization of the non-polar storage lipids triacylglycerols (TAGs) from lipid particles by hydrolysis of TAGs, releasing and supplying specific fatty acids to the appropriate metabolic pathways.
What are the official names of this protein?
Triacylglycerol lipase ptl3.
What are the subcellular locations of this protein?
Cytoplasm. Lipid droplet.
Protein: ATG27_YEAS7
Sequence: MVSKTWICGFISIITVVQALSCEKHDVLKKYQVGKFSSLTSTERDTPPSTTIEKWWINVCEEHTVEPPEDCKKNDMLCGLTDVILPGKDAITTQIIDFDKNIGFNVEETESALTLTLKGATWGANSFDAKLEFQCNDNMKQDELTSHTWADKSIQLTLKGPSGCLKSKDDDKKNGDGDNGKDGDNEGKKPAKKAGGTLWFTWLFLYALLFTLIYLMVVSFLNTRGGSFQDFRAEFIQRSTQFLTSLPEFCREVVSRILGRSTAQRGGYSAV
What is the function of this protein?
Effector of VPS34 phosphatidylinositol 3-phosphate kinase signaling.  Regulates the cytoplasm to vacuole transport (Cvt) vesicle formation.  Plays a role in ATG protein retrieval from the pre-autophagosomal structure (PAS) and is especially required for autophagy-dependent cycling of ATG9 (By similarity).
What are the official names of this protein?
Autophagy-related protein 27.
What is the protein family that this protein belongs to?
Belongs to the ATG27 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Mitochondrion membrane; Single-pass membrane protein. Preautophagosomal structure membrane; Single-pass type I membrane protein. Note=Cycles among the pre-autophagosomal structure (PAS), mitochondria and Golgi.
Protein: OAT_BORBR
Sequence: MPAPAATRRDRIEDELGAHNYQPLDVVLARGSGVWLYDTAGRRYLDCLSAYSAVNQGHCHPRILAAMVEQAQRLTLTSRAFRHDQLAPLYEDLARLTGAHKVLPMNSGAEAVETALKAVRKWGYEARGVPAGQAEIIVCANNFHGRTLGIVGFSTDPDARGGYGPFAPGFTVVPFGDFAALQAAVTPRTVAFLVEPIQGEAGVILPPPGYFRQVRKLCSERDIVLILDEIQTGLGRTGAFLAEAHEGIEADVTLIGKALSGGFYPVSAVLSNQAVLGIFQPGQHGSTFGGNPLACAVARAALRVLHDEGMIDNAREQGAYFMQRLRALPGPVREVRGRGLMLALELEPDAGPARAYCERLMARGMLVKDTHGQTLRLSPPLIVTREQIDWACAQLAHVLAHSAPGSSGGPS
What is the function of this protein?
Catalyzes the interconversion of ornithine to glutamate semialdehyde.
What are the official names of this protein?
Ornithine aminotransferase, OAT, Ornithine--oxo-acid aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KGP24_DROME
Sequence: MRFCFDRLCFATKRPAQNSNSNAPHSSTTVDAPPRPADVDVATVPVATPAPPPQQPVSNLFYADYQKLQPAIIDRDWERDRDTDTDTRSEAKPPDIVEHIEPVEEQRQIHTQIQSPAEIQIQIPPTPPAPSIQIQIQQRYRRHSSAEDRNLNTRRNDSNITEALRKAASMQQEPNANYQFPTDLGLVSIVNNNNNTNTHPSGSNSGSNNNSNINNNLVGGIVTLPAAGGLIGLEHTASGLRLIPAPPTHSDVLTHTLIYGTPPSGAQQLNQDPRSLLHQQELQLQQRYQQLQQLQAQTQGLYTSQGSPVLYHQPSPGSSQPVAIPGATCHSPTQLQPPNTLNLQQQMQSLRISGCTPSGTGGSATPSPVGLVDPNFIVSNYVAASPQEERFIQIIQAKELKIQEMQRALQFKDNEIAELKSHLDKFQSVFPFSRGSAAGCAGTGGASGSGAGGSGGSGPGTATGATRKSGQNFQRQRALGISAEPQSESSLLLEHVSFPKYDKDERSRELIKAAILDNDFMKNLDLTQIREIVDCMYPVKYPAKNLIIKEGDVGSIVYVMEDGRVEVSREGKYLSTLSGAKVLGELAILYNCQRTATITAITECNLWAIERQCFQTIMMRTGLIRQAEYSDFLKSVPIFKDLAEDTLIKISDVLEETHYQRGDYIVRQGARGDTFFIISKGKVRVTIKQQDTQEEKFIRMLGKGDFFGEKALQGDDLRTANIICESADGVSCLVIDRETFNQLISNLDEIKHRYDDEGAMERRKINEEFRDINLTDLRVIATLGVGGFGRVELVQTNGDSSRSFALKQMKKSQIVETRQQQHIMSEKEIMGEANCQFIVKLFKTFKDKKYLYMLMESCLGGELWTILRDKGNFDDSTTRFYTACVVEAFDYLHSRNIIYRDLKPENLLLNERGYVKLVDFGFAKKLQTGRKTWTFCGTPEYVAPEVILNRGHDISADYWSLGVLMFELLTGTPPFTGSDPMRTYNIILKGIDAIEFPRNITRNASNLIKKLCRDNPAERLGYQRGGISEIQKHKWFDGFYWWGLQNCTLEPPIKPAVKSVVDTTNFDDYPPDPEGPPPDDVTGWDKDF
What are the official names of this protein?
cGMP-dependent protein kinase, isozyme 2 forms cD4/T1/T3A/T3B, cGK, Foraging protein.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.
Protein: FEMX_STAAU
Sequence: MEKMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEVQGVAQLLFKKVPKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDVEVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLNSFERRNRSKVRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGDAELFLVKLDPKENIAKVNQELNELHAEIAKWQQKMETSEKQAKKAQNMINDAQNKIAKNEDLKRDLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGATTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYILNQPLYQLIEQVKPRLTKAKIKISRKLKRK
What is the function of this protein?
Catalyzes the incorporation of the first glycine of the pentaglycine interpeptide bridge, which is characteristic of the S. aureus peptidoglycan.  This glycine is added to the epsilon-amino group of the L-lysine of the membrane-bound lipid II intermediate (GlcNAc-(beta-1,4)-N-acetylmuramic acid(-L-Ala-D-iGln-L-Lys-D-Ala-D-Ala)-pyrophosphoryl-undecaprenol), using glycyl-tRNA(Gly) as donor, in a ribosome-independent mechanism (By similarity).
What are the official names of this protein?
Lipid II:glycine glycyltransferase, Factor essential for expression of methicillin resistance X.
What is the protein family that this protein belongs to?
Belongs to the FemABX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR18_ARATH
Sequence: MNKSKRLFTKSKRSFRRRLPPIQSGDRIDYRNMSLISRFISEQGKILSRRVNRVTLKQQRLITIAIKQARILSLLPFLNNQKQFERSESTPRTTSLRTRKK
What are the official names of this protein?
30S ribosomal protein S18, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.