PharMolix/UniProtQA huggingface dataset:
Protein: GRPE_BURMS
Sequence: MENTQENPTDQTTEETGREAQAAEPAAQAAENAAPAAEAALAEAQAKIAELQESFLRAKAETENVRRRAQDDVAKAHKFAIEGFAENLLPVLDSLEAAVGDTSGDLAKVREGVELTLRQLTSALEKGRVAALNPVGEKFDPHLHQAISMVPADQEPNTVVAVLQKGYTIADRVLRPALVTVAQPK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSF1_PHANO
Sequence: MYGETANKLVQNAKRTQALPHLPPYASDLSRTIVREVRDLDRDVSAILAPYGSSFNPSADPSTACALLVNHLCMRRNKRCLLAYHKVRTEKLEGYCWEGIDILEQTGSGKEGEGGMAGKKEESSLSPEEEEYVRQYSDLLAAYKGQWTDIDLTGSLEPPRDLFIDVRVLKDAGEIQTEYGSITLTKNSQFYVRHGDVERLIAQGYLQRLS
What is the function of this protein?
The GINS complex plays an essential role in the initiation of DNA replication.
What are the official names of this protein?
DNA replication complex GINS protein PSF1.
What is the protein family that this protein belongs to?
Belongs to the GINS1/PSF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS5_LEPBJ
Sequence: MAYQDEESKEYSEKVVKIDRVAKVVKGGRRFSFNALSVVGDQKGKVGIGFGKANEVPDAIRKSIEAAKKHLVKINFKGHTIPHEVVGKFKSARVILKPSTAGTGIIAGASVRSIVEKAGIQDVLTKSWGSSNPVNIVKATLDALEQLETPILAAKKRGISLNQLFGKD
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: DCTP_SHELP
Sequence: MTRLNTCTFIKQIVKMTSIAALLGASLNSWAAPTEIKFSHVVAENTPKGQMALKFKQLVEERLPGEYQVNVFPNSQLFGDNNELSALLLNDVQFVAPSLSKFERYTKKLQLFDLPFLFKDMDAVNRFQQSDAGQQLLNSMKRKGVVGLGYLHNGMKQFSASSPLVLPEDAQGKKFRIMASDVLAAQFQAVEAIPVKKPFSEVFTLLQTRAIDGQENTWSNIYSKKFYEVQSNITESNHGVLDYMVVTSNTFWKSLPADKRKVIKASLDEAIAYGNEIAAAKVNKDKQAIIDSKRSEVTYLTPEQRAAWVNAMKPVWAQFEDKIGKDLIDAAVASNE
What is the function of this protein?
Part of the tripartite ATP-independent periplasmic (TRAP) transport system DctPQM involved in C4-dicarboxylates uptake (By similarity).  Required for the utilization of succinate, fumarate, L-malate and alpha-ketoglutarate (PubMed:29769716).  Binds succinate and malate (PubMed:25540822).
What are the official names of this protein?
C4-dicarboxylate-binding periplasmic protein DctP.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 7 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: ATPB_ACIBC
Sequence: MSSGRIIQIIGAVIDVEFERTSVPKIYDALQVDGTETTLEVQQQLGDGVVRTIAMGSTEGLKRGLTVTSTNAPISVPVGTATLGRIMDVLGRPIDEAGPVATEERLPIHRQAPSYAEQAASTDLLETGIKVIDLLCPFAKGGKVGLFGGAGVGKTVNMMELINNIAKAHSGLSVFAGVGERTREGNDFYHEMKDSNVLDKVAMVYGQMNEPPGNRLRVALTGLTMAEYFRDEKDENGKGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKSGSITSIQAVYVPADDLTDPSPATTFAHLDATVVLSRDIASSGIYPAIDPLDSTSRQLDPLVVGQEHYEIARAVQNVLQRYKELKDIIAILGMDELAEEDKLVVYRARKIQRFFSQPFHVAEVFTGAPGKLVPLKETIRGFKGLLAGEYDHIPEQAFYMVGGIDEVIAKAEKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: IF1_LATSS
Sequence: MAKDDVIEIEGKVTDTLPNAMFKVELENGAVILAHVSGKIRKNYIKILPGDRVTVELSPYDLTKGRITYRFK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CINAL_CHLP8
Sequence: MKAVIISIGDELLKGHRVNTNAPFIARQLGTIGIPVSRIITCSDDPQSIRVAVTSALEEAEAVLMTGGLGPTNDDRTRTTVQELLGRGLVFDEPSFERIAEMFRRRGRPVTEAMKAQAMVIEGSVTVPNTKGTAPGMIIECAPQFAGRYLVLMPGVPVEMEAMMQLTVIPFFEPLSGAFIRHTPIMTMGIGESQLSGLIAQVEDELPSGTTLSYLPHAAGVSLMVSTSGSRKEEVDEQNRRVVDAIVERARSFVYAIRDARLEEVVVETLLEKKMTVAVAESCTGGLIASRLTDVAGSSGCFLQGLVTYSNEAKVAQLGVDPLTIEELGAVSEPVAEEMARGCLERSGADIAVSTTGIAGPGGGSPEKPVGTVCIAVASRSGKGDVTVEASTFSMHGDRQQNKARFSEAALRALLVRLKQPGS
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: IF4E1_CUCME
Sequence: MVVEDSMKATSAEDLSNSIANQNPRGRGGDEDEELEEGEIVGDDDLDSSNLSASLVHQPHPLEHSWTFWFDNPSAKSKQATWGASIRPIYTFSTVEEFWSVYNNIHHPSKLAMRADLYCFKHKIEPKWEDPVCANGGKWTVNFPRGKSDNGWLYTLLAMIGEQFDCGDEICGAVVNVRSGQDKISIWTKNASNEAAQASIGKQWKEFLDYNESIGFIFHDDAKKFDRHAKNKYMV
What is the function of this protein?
(Microbial infection) Susceptibility host factor required for viral infection by recruiting viral RNAs, including uncapped and non-polyadenylated RNA, to the host ribosomal complex via an interaction with viral genome-linked protein (VPg).
What are the official names of this protein?
Eukaryotic translation initiation factor 4E-1, Cm-eIF4E, eIF-4E-1, eIF4E-1, eIF-4F 25 kDa subunit, eIF-4F p26 subunit, mRNA cap-binding protein.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic initiation factor 4E family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: HACD_ARATH
Sequence: MAGFLSVVRRVYLTLYNWIVFAGWAQVLYLAITTLKETGYENVYDAIEKPLQLAQTAAVLEILHGLVGLVRSPVSATLPQIGSRLFLTWGILYSFPEVRSHFLVTSLVISWSITEIIRYSFFGFKEALGFAPSWHLWLRYSSFLLLYPTGITSEVGLIYLALPHIKTSEMYSVRMPNILNFSFDFFYATILVLAIYVPGSPHMYRYMLGQRKRALSKSKRE
What is the function of this protein?
Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle.  This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle.  This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation.  Thereby, it participates in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.  May be an anti-phosphatase that prevents CDKA-1 dephosphorylation and activation.  Involved in the hormonal control of cell division and differentiation.  Required for proliferation control of meristematic and non-meristematic cells.  Negative regulator of the cell cycle.
What are the official names of this protein?
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase PASTICCINO 2, 3-hydroxyacyl-CoA dehydratase PASTICCINO 2, AtPAS2, HACD, HCD, Protein PEPINO, PEP, Protein tyrosine phosphatase-like protein.
What is the protein family that this protein belongs to?
Belongs to the very long-chain fatty acids dehydratase HACD family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cytoplasm. Nucleus. Note=Found in the cytoplasm of dividing cells but moves into the nucleus upon cell differentiation.
Protein: DHOM_EMENI
Sequence: MSAPIYLGVIGVGGVGTAFLNQLARLPNAPKLILLARSSQTLLSPTPSYSPTIPAAEWKTAVETPSLTKSGALTPDEIATYLASAPGRSILVDNTSDPALASNYPVFLRKGISVVTPNKKGFSSDLSLWKEIFAAAAEGKALVYHESTVGAGLPVISTLKDLVNTGDEVTRIEGVFSGTLSFLFNTFAPASGSSSAKWSEVVSQAKELGYTEPDPRDDLNGMDVARKLTILARIAGLDVQSPDSFPIESLIPAELTSLPSSADGIAQFMARLPEFDSQMAAIKEGAEKAGKVVRYVGSVDVAKKEVRVGLQQFDKDSAIAGLKGSDNIISFYTRRYGSNPLIVQGAGAGGDVTAMGVTADLLKVIERL
What is the function of this protein?
Involved in osmoadaptation.
What are the official names of this protein?
Homoserine dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the homoserine dehydrogenase family.
Protein: RR12_SPIMX
Sequence: MPTIQQLIRNKRQAAENKTKSPALQRSPQRRGVCTRVYTTTPKKPNSALRKVARVRLTSGFEVTAYIPGIGHNLQEHSVVLVRGGRVKDLPGVRYHIVRGTLDVVGVKDRRKGRSKYGVKRPK
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits (By similarity).
What are the official names of this protein?
30S ribosomal protein S12, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ODAD4_XENLA
Sequence: MAEETDEQQAPQSTFSTYMAEGEQLYHKAEYKKASDSFTAALQLQPEEKNCLVARSKCFLKLGEPECALKDAEASLQIENDFFKGLYQKAEALYAMGDFEFALVHYHRGYKLRPEFQGFRLGIQKAQEAIENSVGTPASVKLENKTDLQFISRQEESKKAKQKAQVKVQKKDSKQQKKVDPERSQKTVRQLLGELYSDKEYLESLLRDEALVKGNTRGGVKLHDLIINGILYLDTRSEFWRQQKPIYARQRDRKIMQQKWKRDKNKSADPSQYIVKSLEEIDQLLSSGKAEESYKKAQLVLKKVERWTSVDIHNREELTGSLHSCIGNAQMDMGQIEAALQSHKKDLAIAEKYKLLEAKSRALDNIGRVYARIGKFNEAIKVWEEKIPLANSSLEKTWLYHEIGRCYLELEQTAEAKEYGEKSQQEADAAEDIEWQLNACVLLAQAEVKLKHYQSAISSFENALERARLLHNKDAEQAILVALEDAKQGMEEQQESEQNNDENDNLRADGNTARDEEEEDVHVQRTEEDEG
What is the function of this protein?
Required for the docking of the outer dynein arm to cilia, hence plays an essential role in cilia motility.
What are the official names of this protein?
Outer dynein arm-docking complex subunit 4, Tetratricopeptide repeat protein 25, TPR repeat protein 25.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Note=In addition to ciliary axonemes, also detected in foci, presumably basal bodies, at the apical cell surface.
Protein: OTC_STRS7
Sequence: MTQVFQGRSFLAEKDFTREEFEYLIDFAAHLKDLKKRGIPHHYLEGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMFDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVKENFGKLEGLTLVYCGDGRNNVANSLLVAGTLLGVNVHIFSPKELFPAEDIVKLAEGYAKASGAHVLVTDNADEAVKGADVLYTDVWVSMGEEDKFEERVKLLKPYQVNMELVKKADNDNLIFLHCLPAFHDTNTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLFIPKV
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KITH_MANSM
Sequence: MAKLYFYYSTMNAGKSTTLLQSAYNYNERNMNTLVYTAAIDDRFGAGRVTSRIGISQQAKLFNRESNLFEEIKRHLASEKLHCILIDEAQFLTKQQVYQLSDVVDLLNIPVLCYGLRTDFQAELFEGSQYLLAWADQLEELKTICHCGRKANFVLRLNERGDVVKDGEQIQIGGNERYLSVCRFHFKQKTGKLHN
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEF_RICBR
Sequence: MTLSNSALGKKSTYKDTYDPTLLFKIPRIDNRKELGIVNDKLPFHGVDIWNAYELSWLDKKGKPCVAIFTFFVPTTSSHIVESKSVKLYLNSFNNFVVDSMEELKRTILQDLSNNTHAEVTGEIFPINTKIEFGSPTGINIDDIDIECSEYGPPNNSLIKHEDVLVEEELNSNLLKSNCLVTGQPDWGTIIIKYKGKKLKHDALLKYLVSFRNCNEFAEQCAERIFTDIKNAINPEFLSIYIIYTRRGGIDICPYRSTDSNYTLPSSKRLIRQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCPB_STRGC
Sequence: MSKLSEIEALLFVAGEDGLKVRQIAEILSIPPTGVSQSLEKLTAKYEADADCSLALLETSNTYKLVTKQAFAELLRAYSKSPINQSLSRAALETLSIIAYKQPITRVEIDDIRGVNSSGALAKLLAFELVREDGKKEVLGRPNLYVTTEYFLDYMGINHLEELPVVTDTELVAEESQLFGQATESELE
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein B.
What is the protein family that this protein belongs to?
Belongs to the ScpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: LPXK_NEIM0
Sequence: MPNCFKFHTVIERHWQKPYPVLSFLLKPLSGLFAKIAAKRRTDFLSGKRQSEKLPVPVVVVGNIHAGGTGKTPIVAALVSGLQEKGVKVGIISRGYGRKSKAVHVLNAESRAEDAGDEPLLLFRKTGAPTAVGSSRAEAGRALLAAHPDIGLIVADDGLQHYALRRDVEIAVFPAADTGRTDLDLLPNGSLREPLSRLDSVDTVVVSGGKADALFRPSENMFHSRIEVGRIYRLNNPSEILDTGRLKNQTVVAVAGIAKPARFFDSLRNMGITVKRTVALPDHADISAADLPDADAVIITEKDAVKFSDGICTDNVWVLPVCAIIEPDLAAFVLERLEDVPKAV
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: LPQB_CUTAK
Sequence: MTLRPSRRAVLSAAAVLLTGCSEVPSQGPVKRADGPRAAAQESIDVAPHPPADGASIDLVVGGFLQAMASARDDYRVARSYLTSDIADRWDPHAKVTIYDATNHKPASTVATAALQAPVVGQIDSRGHYHPTSSQTLNHDFGMAQESGQWRISRPPEGVLISQYTFQRSWSTIPIYFLTEAADRLVPDVIHLPSAAADPDAALRAMTAGVPKPLDAVLRTALPDGVTVTGTTSVDAVGVVTVPLSASAAQLSPSQRRLLASQVTWTLNGFAAISRVRFTAGGSLLSLPEAAEDQTVSADLYAEFIPLPATHSPTVVAVIKGQMGRVAASGHNFQIMPGALGREATTNNSVAEVASTQLTMPMISPRSPGAVWHAVSADRRSLLTWQEGSEDIQVLATGVNLLRPQVLGDHSIMTFSDTDPTLIVIGSDGTRMSTVVDLGGRRVRSFSVAPDAVQVALVLERGKTRALGIGLLSRQEGAVHLSHIADIPLSSSDVNLSIITDVAWLSQTRLCVLGRAIDAGVTTPYEIAVDGSGATSMGQLTATSMAAVVALPKETGTEAVVLSEDGILLRHEDSFRWRQILQGVSAVAVTA
What are the official names of this protein?
Lipoprotein LpqB.
What is the protein family that this protein belongs to?
Belongs to the LpqB lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: GLGA_CHLT2
Sequence: MKIIHTAIEFAPVIKAGGLGDALYGLAKALAANHTTEVVIPLYPKLFTLPKEQDLCSIQKLSYFFAGEQEATAFSYFYEGIKVTLFKLDTQPELFENAETIYTSDDAFRFCAFSAAAASYIQKEGANIVHLHDWHTGLVAGLLKQQPCSQLQKIVLTLHNFGYRGYTTREILEASSLNEFYISQYQLFRDPQTCVLLKGALYCSDFVTTVSPTYAKEILEDYSDYEIHDAITARQHHLRGILNGIDTTIWGPETDPNLAKNYTKELFETPSIFFEAKAENKKALYERLGLSLEHSPCVCIISRIAEQKGPHFMKQAILHALENAYTLIIIGTCYGNQLHEEFANLQESLANSPNVRILLTYSDVLARQIFAAADMICIPSMFEPCGLTQMIGMRYGTVPLVRATGGLADTVANGINGFSFFNPHDFYEFRNMLLEAVTTYRTNHDKWQHIVRACLNFSSDLETAANKYLEIYKQ
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: GLPK_BRUSU
Sequence: MSGYILAIDQGTTSTRSMLFDRNMRVVGLGQQEFTQHFPSSGWVEHDAEEIWKSVQSTIRIALAQAGISAADVAAIGITNQRETTVVWDRISGKPVHRAIVWQDRRTAQFCDELKRRNLEPLFTEKTGLLLDPYFSGTKLAWLLNHVPGLRERAQKGQVCFGTIDSWLIYKLTGGKAHVTDATNASRTLIYHIGENRWDDELLDILGIPAAMLPEVKDCAADFGMTDPALFGVSIPILGVAGDQQTAVIGNACFEPGMMKSTYGTGCFALLNTGTDRVTSSNRLLTTIAYRLDGVTTYALEGSIFIAGAAVQWLRDEMGFISVVSEVSALAEKADPNQRIYLVPAFTGLGAPYWDAEARGAIFGLTRGTGRAEFARAALESVAYQTFDLLEAMQGDWKGATNHTVLRVDGGMVASDWTMQRLADILNAPVDRPVFLETTVLGAAWLAASRAGIWPDRKGFSERWQRDCRFEPAMPEKERESAIAGWRDSVSRCLTRPQ
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: Y1008_BACP2
Sequence: MGTHLHITAWVLGIILFFVAFALAGKNDKGAKIVHMIVRLLYLIIIATGVELYVRTGMKIPGFGGEYIGKMILGILVIGFMEMTLVRKKKGKSVTGVLIGFIIFAIVTILLGLRLPIGFHIF
What are the official names of this protein?
UPF0344 protein BPUM_1008.
What is the protein family that this protein belongs to?
Belongs to the UPF0344 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYW_NEIMB
Sequence: MSKKRVLTGVTTTGIPHLGNYVGAIRPAVRAAQNLDTESFLFLADYHGIIKCHEPEMIHQSTQAVAATWLACGLDPERTTFYRQSDTPEVMELNWILTCITAKGLMNRAHAYKAAVQANAENGQEDPDFGVEMGLFSYPILMTADILMFNANEVPVGRDQIQHVEMARDIAGRFNHRFRELFTLPEVKIDENVELLVGLDGRKMSKSYGNTIPLWENDKKTQKSVNKIITNMKEPGEPKQPDESPLFEIYKAFSTPSETVEFTKMLADGLAWGEAKKLLAAKINAELAEPRERYNELTADPSQIEEILQAGAAKARKEARELLDKVRDAVGIRPLK
What is the function of this protein?
Catalyzes the attachment of tryptophan to tRNA(Trp).
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: END4_MYCGE
Sequence: MPKLLGSFISFKAPNYFVQSAQDAIAIDATALMVFLGPPHSAYRVPFNKMQFSLGYELLKTKNINSNGLVVHAPYIINCASKDPLKQQNAISVLTNEIQLCNLAGAHYLVLHPGSAVAQTTNEALDNLVKVLNQVINKTKTTVICLETMAGKGNEIGRDLTELKYVIDRIVDKDRIGVCLDTCHFHDSGIDFSDLTGVFNTITTKLGFEFLKVIHLNESKNNCGSKKDRHANINAGMIGFENLMKFISHPQIKDLPIILETPSTSLNYPTIYREEISQIRSWFKTYQPDAN
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: YD048_YEAST
Sequence: MSSLLQLLAVWSQSSSISMNSEVAQTNQKYKDHSFLVSQSFYSPFVNSCYWKLVNRRADLLKILFLRRKGDMHSHLFSYTFIFYFLLFKILSLHPFREPAKINI
What are the official names of this protein?
Putative uncharacterized membrane protein YDR048C.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: GPAT2_ARATH
Sequence: MSGNKISTLQALVFFLYRFFILRRWCHRSPKQKYQKCPSHGLHQYQDLSNHTLIFNVEGALLKSNSLFPYFMVVAFEAGGVIRSLFLLVLYPFISLMSYEMGLKTMVMLSFFGVKKESFRVGKSVLPKYFLEDVGLEMFQVLKRGGKRVAVSDLPQVMIDVFLRDYLEIEVVVGRDMKMVGGYYLGIVEDKKNLEIAFDKVVQEERLGSGRRLIGITSFNSPSHRSLFSQFCQEIYFVRNSDKKSWQTLPQDQYPKPLIFHDGRLAVKPTPLNTLVLFMWAPFAAVLAAARLVFGLNLPYSLANPFLAFSGIHLTLTVNNHNDLISADRKRGCLFVCNHRTLLDPLYISYALRKKNMKAVTYSLSRLSELLAPIKTVRLTRDRVKDGQAMEKLLSQGDLVVCPEGTTCREPYLLRFSPLFSEVCDVIVPVAIDSHVTFFYGTTASGLKAFDPIFFLLNPFPSYTVKLLDPVSGSSSSTCRGVPDNGKVNFEVANHVQHEIGNALGFECTNLTRRDKYLILAGNNGVVKKK
What is the function of this protein?
Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis.
What are the official names of this protein?
Probable glycerol-3-phosphate acyltransferase 2, AtGPAT2.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Note=Not mitochondrial.
Protein: CLPP1_CHLMU
Sequence: MPEGEMMHKLQDIIDRKLLDSRRIFFSEPVTEKSAAEAIKKLWYLELTSPGQPIVFVINSPGGSVDAGFAVWDQIKMISSPVTTVVTGLAASMGSVLSLCAAPGRRFATPHARIMIHQPSIGGTITGQATDLDIHAREILKTKARIIDVYVEATGQSREVIEKAIDRDMWMSANEAMEFGLLDGILFSFNDL
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 1, Endopeptidase Clp 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRG8_CANGA
Sequence: MPRLERNVYKGLITSLSRKKPSNSLAVKESPLLTKFERWSGKRMKLFFESEDSFEHYGLRDLKLPHNMLANKLASPIRAERNTRYRIPKEFLIKLNLYKDATNNVLQLKANFNGVTGLGTTYIHNNKKCLEMKFCDISRWSSRQPLKVPPLPIVADKSALLKDYENQLIRELNECFSKLKTTSKHDHNTVKLYVSTENNLLMDVDTQGSLCINLQSITDKLPHTMLETVTNAPIHISAYSNMDFLTTLHRLLGYYRHRNR
What is the function of this protein?
Required for respiratory activity and maintenance and expression of the mitochondrial genome.
What are the official names of this protein?
Required for respiratory growth protein 8, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RRG8 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: DAPE_MYCTU
Sequence: MLDLRGDPIELTAALIDIPSESRKEARIADEVEAALRAQASGFEIIRNGNAVLARTKLNRSSRVLLAGHLDTVPVAGNLPSRRENDQLHGCGAADMKSGDAVFLHLAATLAEPTHDLTLVFYDCEEIDSAANGLGRIQRELPDWLSADVAILGEPTAGCIEAGCQGTLRVVLSVTGTRAHSARSWLGDNAIHKLGAVLDRLAVYRARSVDIDGCTYREGLSAVRVAGGVAGNVIPDAASVTINYRFAPDRSVAAALQHVHDVFDGLDVQIEQTDAAAGALPGLSEPAAKALVEAAGGQVRAKYGWTDVSRFAALGIPAVNYGPGDPNLAHCRDERVPVGNITAAVDLLRRYLGG
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid.
What are the official names of this protein?
Putative succinyl-diaminopimelate desuccinylase DapE, SDAP desuccinylase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family.
Protein: HISX_NEIMA
Sequence: MKKLNTQSPDFQAGLKALLAFETAQNPETERIVADICADVQKRGDAALIEYTNKFDQTNAKSIDDLILTQADLKAAFERIPNDVQTALQTAARRVESYHQRQKMESWSYTDEDGTLLGQQITPLDRVGIYVPGGKAAYPSSVIMNAMPAHVAGVKEIIMVVPTPKGERNDIVLAAAYVAGVTKVFTVGGAQAVAALAYGTETIPQVDKITGPGNAFVAAAKRRVFGVVGIDMVAGPSEILVIADGTTPADWVAMDLFSQAEHDEIAQAILIGTSQAYLDEVEAAMDRLIETMPRRDIIEASLGNRGAMILAKDLDEACEIANYISPEHLELSVENPQEWAKKIRHAGAIFMGRYTGESLGDYCAGPNHVLPTSRTARFSSPLGTYDFQKRSSLIQVSEQGAQKLGETASVLAHGESLTAHARAAEFRMK
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: GSA_BDEBA
Sequence: MHKVTSEELFQRALKVAPGGVHSPVRSFKGLDRAPVFFKKAEGAYLTSVEDKKYIDFCQSFGPLILGHLDAEVKEEVHRMVDTAWTFGATEIYSLELAEWITSTLPFMEKLRFVSSGTEAVMSALRVARAATGRTKILKFEGCYHGHVDNLLVKAGSGLAGTAASSSAGIPAEVAAHTVVAPLDDEAKLAEVFAAQGKDIAAVIIEPLPANYGLLVQRPEFLKKVAELCEKNGSLLIFDEVISGFRVGLGGMVEKTGIRPDLVTYGKIIGGGFPVGCYGGKAELMNMVAPSGDVYQAGTLSANPIGMRAGLTTLKKMQRVDGWNVLEQRTKKFTDAIKAGFVKKGVNLEISQVASLFWIHGPTASPIRSIDHIPANQGGNFKNLFLKALDKGVYLAPNAYEVGFVSLAHSDELLEQAAQIIVDAAE
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.