PharMolix/UniProtQA huggingface dataset:
Protein: G3P2_STAES
Sequence: MATNIAINGMGRIGRMVLRIALNNKNLNVKAINASYPPETIAHLLNYDTTHGVYDKKVEPIESGIKVNGHEIKLLSDRNPENLPWNEMDIDVVIEATGKFNHGDKAVAHINAGAKKVLLTGPSKGGDVQMIVKGVNDNQLDIDTYDIFSNASCTTNCIGPVAKVLNDKFGIINGLMTTVHAITNDQKNIDNPHKDLRRARSCNESIIPTSTGAAKALKEVLPEVEGKLHGMALRVPTKNVSLVDLVVDLEQNVTVTQVNDAFKNADLSGVLDVEEAPLVSVDFNTNPHSAIIDSQSTMVMGQNKVKVIAWYDNEWGYSNRVVEVAVKIGQLIDDKAMVKAI
What is the function of this protein?
Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD.  The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH.  The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase 2, GAPDH 2, NAD-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMI_SALNS
Sequence: MTESTFPQYPRLVLSKGREKSLLRRHPWVFSGAVSRLEGKANLGETIDIVDHQGKWLARGAWSPASQIRARVWTFDKAESIDIAFFTRRLRQAQQWRDWLAKKDGLDSYRLIAGESDGLPGVTIDRFGHFLVLQLLSAGAEYQRAALISALQTCYPDCAIYDRSDVAVRKKEGMALTQGPVTGELPPALLPIEEHGMKLLVDIQGGHKTGYYLDQRDSRLATRRYVENQRVLNCFSYTGGFAVSALMGGCRQVVSVDTSQDALDIARQNVELNQLDLSKAEFVRDDVFKLLRAYRERGEKFDVIIMDPPKFVENKSQLMGACRGYKDINMLAIQLLNPGGILLTFSCSGLMTSDLFQKIIADAAIDAGRDVQFIEQFRQAADHPVIATYPEGLYLKGFACRVM
What is the function of this protein?
Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase I, 23S rRNA m5C1962 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RlmI.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_STAA8
Sequence: MDLKQYVSEVQDWPKPGVSFKDITTIMDNGEAYGYATDKIVEYAKDRDVDIVVGPEARGFIIGCPVAYSMGIGFAPVRKEGKLPREVIRYEYDLEYGTNVLTMHKDAIKPGQRVLITDDLLATGGTIEAAIKLVEKLGGIVVGIAFIIELKYLNGIEKIKDYDVMSLISYDE
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFB_LEPIN
Sequence: MKLSLDWMNDFTPLKEVGLDAILKKIAISVCEIDDATEFRPELDFVKIVRIESLEKHPSADKLQIVQVFDGSSKSQIVTGATNVKIGDLVPLAIPGAKLGDKEILESELRGVKSSGMLCSEKELFLSEEGNGVWILNGLDQAEVGKTIRSFLYYDDIIFEVDNKSITHRPDLWSHFGFARELASQLRLPIVFNPFESLWNFDLSVKLPKVLENQNAHSYYASSISGVSVFPSKRKFQSRLQKCGVRVINNVVDVSNYVMLEMGQPTHFFDKKFLENQGEISLEVSFAKKGESFALLDETSPALEEEVLLIRNQGKPVAIAGVMGGKESAVQNTTTEIVMESAVFMRERIRKSIRSTGIRSDSSVRYEKGLEATTTLPVIRRALNLLKENGCSELKASEPVGFLHIPHKEVRIHTDIHFINAKLGVTLSQGDITDILERLHFIVSWKGEHLEVLVPKFRHNYDVTIPEDLVEEIGRTKGYDTIQVSPLLAEVKTPIRNLNRELERKCKTFFAIALKYHEVFNYSFQSYKENEFSGDPKLSVKIKNEMPEEQSVLRNSLLPSLLKNTRTNQDRFSEIKIFEFGRVYFNLPEPENEKKIFAFAVSLDKKSSEPDLKLLEEDFLKIKKEVESFLESIQIYEYTWKIQQETIFHPGANLCLVARSGKDGLETIVGNLGYVHPAILDSFELKKRVIYGSFEFERIVELWNQNRKVSRFVTPSQFPEAEIDLSILVGEKENTNVFTDLVKLERIPELKEGWVYSQFMGGNVPEGKKSVSYRFRLVNYERTFTQERIKEISDQLVILAGKNGFVLR
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS7_ACIBY
Sequence: MRNVSMTQRISEVVRNTNETKIRVRLNLDGTGQGTLNTGVPFLDHMIDQIKRHGLFDIDIHCDGDLEIDDHHTVEDCGITLGQAFAQALGDKKGLRRYGHFYAPLDEALSRVVVDLSGRPGLFMDIPFTRARIGTFDVDLFSEFFQGFVNHALMTLHIDNLKGKNSHHQIESVFKALARALRMACEIDPRAENTIASTKGSL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOLB_PSEA6
Sequence: MTRLTRVLTFLSVVLTASSQASLEIVITEGIDSARPIAIVPFKWNGPGQMPESLSEVVSGDLLRSGKFSPIDSTDMPGQPHNDNELDYSAWAATGVEAILVGSVTPEGPDRYRVNFTLVDAIRGQITGGNARALSGGKLTNSNDHILDSRQTVITGQGFRQYAHRISDVVYEKLTGEKGAFMTRIAYVVVRDRKTNEFPYQLVVADYDGVNETMLLRSKEPLMSPSWSPDGTKLAYVTFENKRSQIYIQDLYTMSRTQMTDFPGINSAPVFSPNGRQLAMVLSKDGNPEIYVMDVASKRLERITRNRAIDTEPSWTPDGKSLIFSSERGGKPQIYRVDLASNNVRRVTFDGEMNLGGTITPDGGRMVMVNRTRGNYHIAAQDLENGNIQVLTKTYLDESPSIAPNGSMIIYSTLHQGKQVLSLVSLDGRFKARLPASDGQVKSPSWSPFLL
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: AROC_CORJK
Sequence: MLFMLRWTTAGESHGQALISMIENLPAGLSVSREDVSYQLARRRLGYGRGARMKFEADEVTFVGGVRHGKTLGSPVAVMIGNTEWPKWTTIMSADPIDESDPEVAKEMASGRGAKLTRPRPGHADFSGMVKYDHDEARPILERSSARETAARVAAGTFARALLREVLGVEVLSHVISIGRSEPYEGPSPEFSDLEGIDASPVRAFDSAVEESMIDEIKAAKKSGDTLGGIVEVVVKGLPIGLGSHVSGDERLDAQLAAALMGIQAIKGVEIGDGFEEARRRGSEAHDEMEAAANGGVHRLSNRAGGLEGGMTNGEELRVRAAMKPISTVPRALKTVDMATGEAATGIHQRSDVCAVPAAGVVAETMVALVLARAVLKKFGGDSVEETKRNVQSYLEYVDTRLDWSAEANDVADGEVADGEIR
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: PTH_NEIG2
Sequence: MSNTIKMVVGLGNPGKEYEQTRHNAGFWFLDELAWKWKASFKEEKKFFGEVARAALPDGDVWLLKPATFMNRSGQAVAALAQFYKIKPEEILVVHDELDIPCGRIKFKLGGGNGGHNGLKDIQAKLGTADYYRLRLGIGHPGDRNLVVGYVLNKPSAEHRRQIDDAVAKSLQAVPDIISGKWEEATRFLHSK
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_SHEWM
Sequence: MRVLGIETSCDETGVAVYDDEQGLLSHTLYSQVKLHADYGGVVPELASRDHVRKIVPLVKQALADANCTLDDIDGVAYTKGPGLVGALLVGACMGRALAYSWDKPAIGVHHMEGHLLAPMLEDDVPAFPFLALLVSGGHSMLVAVEGIGKYEVLGESVDDAAGEAFDKTAKLMGLDYPGGPRLAKLAAKGESGHYRFPRPMTDKPGLNFSFSGLKTFAANTIAAESDDEQTRANIALAFEEAVVDTLSIKCRRALKQTGYKNLVIAGGVSANTRLRSSLAEMMTSLGGKVYYPRGEFCTDNGAMIAYAGLQRLKAGQTDDLGVKGIPRWPLDTLPPV
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OLM2A_XENTR
Sequence: MWDYKHFLLLSLAFTSTVTALSKVLGDTDQVRMTSEGSDCRCKCIMRPLSKEACSRVKGGNMRVEDYYTVETVSSGSDCKCSCTAPPSSLNPCENEWKMEKMKKQAPELFKLQSMVDLLEGTLYSMDLMKVHSYINKVVSQMNTLEETIKTNLTRENDFMKESVVNLSNQMKKYENYSEIMLSIKKEISNLGYQLLQKDAPENKAQDTAGVKGLAKFPNNKKNEGDKSLSKVTKDKPPKAEKPKKEVSKTKQVPPQPTPRPRSPVLQPVVIRGVTYYKAGRQEDAENAAGNRESVVKGPHRGAKQEIRTEGNITEPYLIREERIVATQRATPTPTPTTTPTTTQSTTTTTTTRTTISTATEYPLTTLSSTVLGAEAETNKVREGECEGTIASVEQPKKQHSYGRNEGAWMKDPIAKDGRIYVTNYYYGNNLVEFRNLDNFKQGRWSNLYKVPYNWIGTGHVVFQGAFYYNRAFTKNIIKYDLKQRFVAAWTLLHDVVYEDTTPWKWRGHSDIDFAVDESGLWVIYPSVDYDYSQQEVIVISKLDPNDLSIKKETTWKTGLKRNSYGNCFIICGILYAVDVYNQKEGMISYAYDTHTDTEADPKLPFINEYAFTTQIDYNPKEKVLYAWDNGHQLTYKVNFVA
What are the official names of this protein?
Olfactomedin-like protein 2A.
What are the subcellular locations of this protein?
Secreted.
Protein: MATK_STAER
Sequence: MDKLKRDVKEETSRQPCFLYPLLFQEDLYAIAYDRHFNRSSSFEPMEDSSYNNRFSFITVKRSISRIRQQNGSIIPFVNCDQNQLVGHNRSFYYELVLGGFTAVLEVPFSIRSKHYIEGMNEWTSFRSINSIFPLMEDKIPHSNYLLEIRIPYLIHPEILVRTFRRWIQDAPFLHSLRSVLHEHRNLIISSNLDQLTLIASKEKKRLSLFLWNYYAYECESLLVPLWKRFYHSRSLSYESFIERTPFYRKIEHIDIFSHKYKHLKKSIWFLKDPSIHYMRYRESSIIALRGTYLLVKKWRYHLTNLWQCHFHLWLRPYRIYIDELSKTNNCFYFLGYLLSVKMKTSVVQIRMLDDSFITDLITKEFDPIAPTTLLIGSWAKEKFGDISGRPISRLAWTGLTDNDILDRFDRIWRNIFHYYRGSSKKDGLYRIKYILRLSCAKTLACKHKSTIRVVRERFGSELFTKSFPKERESIFLSFSKIRSQRERIWHSDIIQRNFLVNS
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: UPP_ENT38
Sequence: MKIVEVKHPLVKHKLGLMREHDISTKRFRELASEVGSLLTYEATSDLATEKVTIEGWNGPVQVEQIKGKKITVVPILRAGLGMMEGVLEHVPSARISVVGIYRNEETLEPVPYFQKLVSNIDERMALVVDPMLATGGSMIATIDLLKNAGCNSIKVLVLVAAPEGIAALEKAHPDVELYTASIDQGLNEHGYIIPGLGDAGDKIFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: RL24_AZOSB
Sequence: MNKIRKGDEVVVLAGKDRGRRGAVLRRVDDERVVVEGVNRVKKHVRPNPLKGEVGGIVEKEMPIHVSNVALFNPAAQKADRVGIKVLEDGRKVRFFKSNGELVDA
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: RL6_ACTSZ
Sequence: MSRVAKAPVNIPAGVQVSLNGQLLTVKGKNSELSRTIHNSVEVKEDNGALTFAPREGFAGADAQAGTARALVNAMVIGVTEGFTKKLQLVGVGYRAQVKGNSISLNLGFSHPVEHTLPAGITAECPSQTEIVLKGADKQLIGQVAADIRAYRKPEPYKGKGVRYADEVVRTKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: PEPQ_SHIFL
Sequence: MESLASLYKNHIATLQERTRDALARFKLDALLIHSGELFNVFLDDHPYPFKVNPQFKAWVPVTQVPNCWLLVDGVNKPKLWFYLPVDYWHNVEPLPTSFWTEDVEVIALPKADGIGSLLPAARGNIGYIGPVPERALQLGIEASNINPKGVIDYLHYYRSFKTEYELACMREAQKMAVNGHRAAEEAFRSGMSEFDINIAYLTATGHRDTDVPYSNIVALNEHAAVLHYTKLDHQAPEEMRSFLLDAGAEYNGYAADLTRTWSAKSDNDYAQLVKDVNDEQLALIATMKAGVSYVDYHIQFHQRIAKLLRKHQIITDMSEEAMVENDLTGPFMPHGIGHPLGLQVHDVAGFMQDDSGTHLAAPAKYPYLRYTRILQPGMVLTIEPGIYFIESLLAPWREGQFSKHFNWQKIEALKPFGGIRIEDNVVIHENNVENMTRDLKLA
What is the function of this protein?
Splits dipeptides with a prolyl residue in the C-terminal position.
What are the official names of this protein?
Xaa-Pro dipeptidase, X-Pro dipeptidase, Imidodipeptidase, Proline dipeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
Protein: KTHY_RHOBA
Sequence: MAGVGIRSYACHRQTRRLLDGDVLMSPGPGNTDMPQTKSSPIAHPYPGRLITLDGIDGVGKSSQIEILAERLRSEGRNVLCVRDPGSTDLGTKLRAMLLDSDLEMHRRTEAMLFMASRCEMIESTLRSALADGVTVISDRFLLANVVYQSVGGEVDAQTLWQLGRLACGGVQPDVTLLLDLPAEISMQRVGGEADRMESRGVDYMAKVRQAFLDELPNAGGRTHVIDASGTIEEVAETIAAIELF
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: GBG14_HUMAN
Sequence: MSSKVAINSDIGQALWAVEQLQMEAGIDQVKMAADLLKFCTEQAKNDPFLVGIPAATNSFKEKKPYAIL
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems.  The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
What are the official names of this protein?
Putative guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-14.
What is the protein family that this protein belongs to?
Belongs to the G protein gamma family.
What are the subcellular locations of this protein?
Cell membrane.
Protein: RS13_SHESR
Sequence: MARIAGINIPDQKHTVIALTAIFGIGRTRARAICAATSIAETAKIKELSEAQIDTLREEVAKYLVEGDLRREISMNIKRLMDLGCYRGLRHRRSLPLRGQRTKTNARTRKGPRKPIKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: RSBW_BACLD
Sequence: MKRAADYIEMKSPAKPEYVGIIRLTLSGIASKMGYSYDDIEDLKIAVSEACTNAVQHAYKADNNTGEVSVRFGVFEDRLEIVVADQGDSFDIQDKQKELGPYSPEHTVDQLSEGGLGLYLMETLMDEVHVQIDSGVTVSMTKFLNRERVDDGTTVQNYETN
What is the function of this protein?
Negative regulator of sigma-B activity.  Phosphorylates and inactivates its specific antagonist protein, RsbV.  Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).
What are the official names of this protein?
Serine-protein kinase RsbW, Anti-sigma-B factor, Sigma-B negative effector RsbW.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-factor family.
Protein: SPRC_CAEEL
Sequence: MRYALAACLLLLAASSFVDAKKKKIADDELGELLDNIDADEEKKSVEPAKNPCEDHQCGWGKECVVGKKGEPTCECISKCPELDGDPMDKVCANNNQTFTSLCDLYRERCLCKRKSKECSKAFNAKVHLEYLGECKKLDECTEEHMAQFPERMADWLFQVMKELKKRRELHKLEWEELLSEAENDDEKKHVYPVIWKFCELDTKPHDKSVSHHELIPITAPVIPMESCIKPFLEGCDANNDGNISIKEWGKCLGLKEGEIQERC
What is the function of this protein?
Has a high affinity for collagen.  Affects nematode body morphology and mobility.  Essential for C. elegans development and muscle function.  The cysteine-rich region could have protease inhibitory activity or may provide the framework for a protein binding module.  Probable role in skeletal morphogenesis.
What are the official names of this protein?
SPARC, Basement-membrane protein 40, BM-40, Osteonectin, ON, Secreted protein acidic and rich in cysteine.
What is the protein family that this protein belongs to?
Belongs to the SPARC family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix, basement membrane. Note=In or around the basement membrane.
Protein: MSCL_CLOB8
Sequence: MFKEFKEFAMKGNMVSLAIGVVIGGAFSKIVTSLVNDIIMPLVGLLMGRVDFSNLFFTLGSGNFKTVQEAKDAGVATVNYGIFINNIIDFLIVAFSIFIIIQQISKLTKKKGENIVPDKKKCKYCYTEINSQATRCPNCTSELKEN
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ASF1_GIBZE
Sequence: MSVVSLLGVNVLNNPAKFVDKYEFEITFECLEQLEKDLEWKLTYVGSATSDQYDQELDSLLVGPIPVGVNKFIFEADAPNISRIPDAEILGVTVILLTCAYDGREFIRVGYYVNNEYDSEELNAEPPVKPIIERVKRNVLAEKPRVTRFAIKWDSEASAPAEYPPEQPEADLVADGDEYGAEEADEEAAEEAEEEAKSKGKASSGEDAEMAGVEHEGENAADEDELSDDGSVDIEGESEDDLEEEEEGEGEGEADGDAMEVDSAEKPATSTAKPVSVAS
What is the function of this protein?
Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.
What are the official names of this protein?
Histone chaperone ASF1, Anti-silencing function protein 1.
What is the protein family that this protein belongs to?
Belongs to the ASF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: VIAAT_RAT
Sequence: MATLLRSKLTNVATSVSNKSQAKVSGMFARMGFQAATDEEAVGFAHCDDLDFEHRQGLQMDILKSEGEPCGDEGAEPPVEGDIHYQRGGAPLPPSGSKDQAVGAGGEFGGHDKPKITAWEAGWNVTNAIQGMFVLGLPYAILHGGYLGLFLIIFAAVVCCYTGKILIACLYEENEDGEVVRVRDSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPGLPVSQKSWSIIATAVLLPCAFLKNLKAVSKFSLLCTLAHFVINILVIAYCLSRARDWAWEKVKFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTHIAACVLKGLFALVAYLTWADETKEVITDNLPGSIRAVVNIFLVAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPACYGGDGRLKSWGLTLRCALVVFTLLMAIYVPHFALLMGLTGSLTGAGLCFLLPSLFHLRLLWRKLLWHQVFFDVAIFVIGGICSVSGFVHSLEGLIEAYRTNAED
What is the function of this protein?
Antiporter that exchanges vesicular protons for cytosolic 4-aminobutanoate or to a lesser extend glycine, thus allowing their secretion from nerve terminals (By similarity) (PubMed:9349821).  The transport is equally dependent on the chemical and electrical components of the proton gradient (PubMed:9349821).  May also transport beta-alanine (PubMed:23919636).  Acidification of GABAergic synaptic vesicles is a prerequisite for 4-aminobutanoate uptake (By similarity).
What are the official names of this protein?
Vesicular inhibitory amino acid transporter, GABA and glycine transporter, Solute carrier family 32 member 1, Vesicular GABA transporter, rGVAT, rat UNC-47 homolog, RUNC-47.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Presynapse. Note=Presents in glycine-, GABA- or GABA- and glycine-containing boutons.
Protein: THII_METAC
Sequence: MPDIFTDNTDKQDSDPSRQGFEGQPNVVIVRYGELALKSTGVRNWYEKILMKNIAAMLDSRNIPYSLLRREWGRIFIETTDPRAAEAAADVFGVVSTSPALVTKPDLESAARTCAFLGTGLIREGESFAIRARRSGNHPFSSADVGRNCGDAVWDSLEKEGKHPRVNLTSPDKEIFVEMRQNLAYVYLETVKGVGGLPLGTQGSMVVLMSGGLDSPVAAWLMMKRGVMITPVYCNNSPYAEDAARERAFDCIRQLQTWAPGHQFATYEIPHGPNLRAFIGTCDRKNTCLLCKRMMYREAYEVMKKVGASGIITGSSLGQVASQTAANMHAEIYQLAIPIYHPLIAFDKSEIVDIARRIGTYDISTRPAGICTAVPERPEVKANYDLIVLEEKKLGIETMVGDALKAVKILKL
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MASZ_MYCGI
Sequence: MTDRVTVGNLRVSPVLYDFINNEALPGTDIDPDTFWSGVDKIVADLTPKNQDLLARRDHLQAQIDKWHRARVIGGFEAEDYKQFLTEIGYLEPEPADFSVTTSGVDDEITTTAGPQLVVPILNARFALNAANARWGSLYDALYGTDVISDEDGAEAGSSYNKRRGDKVIAYARRFLDGAAPLASGSWTDITGLRIDDGAVSATLDDGGSVALADPQQFVGYHGEPDAPTAVLLANNGLHIEILIDADSPIGSTDKAGIKDVVLESAITTIMDFEDSVAAVDADDKVLAYRNWLGLNRGDLAEEVSKGGKTFTRVLNSDRTYRAPDGETELTLPGRSLLFVRNVGHLMTNDAIVVDDNGADGAEVPEGIQDALFTSLIGIHGLRSAGDDDTKNGPLLNSRTGSIYIVKPKMHGPDEVAFTCELFSRVEDVLGLPQNTIKVGIMDEERRTTLNLKACIKAAADRVVFINTGFLDRTGDEIHTSMEAGPMIRKGAMKSTDWIAAYENQNVDIGLETGLSGKAQIGKGMWAMTDLMADMVEQKIGQPKAGATTAWVPSPTAATLHAMHYHQVDVFAVQSELAGKRRSTLDQLLTIPLATELAWAPEEIREEVDNNCQSILGYVVRWIDAGVGCSKVPDIHDVALMEDRATLRISSQLLANWLRHGVITEEDVKTSLRRMAAVVDEQNAADPDFRPMASDPDNSIAFQAAQELILDGAAQPSGYTEPILHRRRREYKAASNVG
What is the function of this protein?
Involved in the glycolate utilization.  Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
What are the official names of this protein?
Malate synthase G.
What is the protein family that this protein belongs to?
Belongs to the malate synthase family. GlcB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TF2H2_CAEEL
Sequence: MDDDEQKGYTWEAGYAEGLNINDVLVEDEGGSIEKSIAKYVADSKRKARLTKRPERIRLGIMRHVMIVIDCSRFMTSKAMPPSRFVVVMKALQTFLDRFFEQNPIAQIGLITCKDRKADRLTMMTGNIRVLKESLNTLTEAFCGGDFSLQNALQLACANLKGMPGHVSREVVLVISALSTIDPGNIYSTIETMKRMNIRCSAIGLSAEMFVCKEMAKATKGEYSVALDPDHLQLLFSKHTLPPSSAKSSECNAIHVGFPHHELITTRSFCVCHPDTKPISSRGFICTQCGARHCSIPAECPVCKLTLVAAPQLARAFRHLQPLSAFEQIEVTRGFCYACETRLSGEGFRCGSCQLVFCLDCDTLLHESLHVCPGCN
What is the function of this protein?
Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.  In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment.  In transcription, TFIIH has an essential role in transcription initiation.  When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.  Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
What are the official names of this protein?
General transcription factor IIH subunit 2, TFIIH basal transcription factor complex subunit 2.
What is the protein family that this protein belongs to?
Belongs to the GTF2H2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYGA_CAMJ8
Sequence: MTFSQMILNLQNYWQEQGCAIMQPYDMPAGAGTFHPATFLRSLGKKPWAAAYVAPSRRPTDGRYGENPNRLGAYYQFQVLIKPSPDNIQELYLKSLENLGFDLKSHDIRFVEDNWESPSLGAWGLGWEVWLDGMEVTQFTYFQQVGGIAVDLVSAEITYGLERIAMYLQNVDNVYDIVWSEFNGEKIKYADVHKQSEYEFSKYNFEVSDVKILNEQFENSYKECKNILEQGLALPAYDYCMLAAHTFNLLDARGAISVAQRQDYMLKIRELSKNCAEIYKKNLNETE
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CECB2_CULPP
Sequence: MNFNKLFLIVILAALLLLGQTEAGRSKKLGKKIEKAGKRVFNAAQKGLPVAAGVQALGR
What is the function of this protein?
Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria.
What are the official names of this protein?
Cecropin-B2.
What is the protein family that this protein belongs to?
Belongs to the cecropin family.
What are the subcellular locations of this protein?
Secreted.