PharMolix/UniProtQA huggingface dataset:
Protein: ASNS_RAT
Sequence: MCGIWALFGSDDCLSVQCLSAMKIAHRGPDAFRFENVNGYTNCCFGFHRLAVVDPLFGMQPIRVRKYPYLWLCYNGEIYNHKALQQRFEFEYQTNVDGEIILHLYDKGGIEKTICMLDGVFAFILLDTANKKVFLGRDTYGVRPLFKALTEDGFLAVCSEAKGLVSLKHSTTPFLKVEPFLPGHYEVLDLKPNGKVASVEMVKYHHCTDEPLHAIYDSVEKLFPGFEIETVKNNLRILFNNAIKKRLMTDRRIGCLLSGGLDSSLVAASLLKQLKEAQVPYALQTFAIGMEDSPDLLAARKVANYIGSEHHEVLFNSEEGIQSLDEVIFSLETYDITTVRASVGMYLISKYIRKNTDSVVIFSGEGSDELTQGYIYFHKAPSPEKAEEESERLLKELYLFDVLRADRTTAAHGLELRVPFLDHRFSSYYLSLPPEMRIPKDGIEKHLLRETFEDSNLLPKEILWRPKEAFSDGITSVKNSWFKILQDFVEHQVDDAMMSEASQKFPFNTPQTKEGYYYRQIFEHHYPGRADWLTHYWMPKWINATDPSARTLTHYKSTAKA
What are the official names of this protein?
Asparagine synthetase [glutamine-hydrolyzing], Glutamine-dependent asparagine synthetase.
Protein: RL18_BLOFL
Sequence: MNKKLLRARRALKLRKKLYLLGSVRLVVYRSLRHMYAQIVSEDNCNVLVAASTTEKLIASKLRVTGNKEAAAVVGQVIAERAFKKGIVHVSFDRSGFKYHGRVQILAEYARQFGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: A1KA1_LOXSA
Sequence: WIMGHMVNAIAQIDEFVNLGANSIETDVSFDKNANPEYTYHGIPCDCGRTCTKWEYFNTFLGGLRKATTPGDSKYHEKLVLVVFDLKTGSLYDNQAYDAGTKLAKSLLQNYWNKGNNGGRAYIVLSIPNLDHYKLITGFKETLTKEEHPELMDKVGYDFSGNDDIGDVAKAYKKAGVTGHVWQSDGITNCLLRGLDRVRKAVANRDSSNGYINKVYYWTVDKRASTRDALDAGVDGIMTNYPDVIADVLSESAYTAKFRIATYDDNPWETFKN
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LsaSicTox-alphaIB1ai, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS10_MYCCT
Sequence: MAENKMRIKLKGYDHAIVDQSITKIIQAAEGTGAKVRGPIPLPTEKQVITILRAVHKYKDSREQFEMRTHKRLLEILNPTAATMDVLKRVQLPSGVDIEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: CD046_MOUSE
Sequence: MADSEEFRASSPPPPPPSSPSSGASSSSLSMPVSLGWRDPSRSPGPTVDPLEQVELQIGDAAFSLTKLLEATSAVSAQVEELALKCTENARFLKTWRDLLKEGYDSLKPDN
What are the official names of this protein?
Uncharacterized protein C4orf46 homolog.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIL2_ECOLX
Sequence: MDAVLSVQGVSAPVKKKSFFSKFTRLNMLRLARAVIPAAVLMMFFPQLAMAAGSSGQDLMASGNTTVKATFGKDSSVVKWVVLAEVLVGAVMYMMTKNVKFLAGFAIISVFIAVGMAVVGL
What is the function of this protein?
Propilin is the precursor of the pilus subunit, pilin, that forms conjugative pili, the filamentous surface appendages required for cell-to-cell contact during the earlier stages of bacterial conjugation, and that retract after contact is established.  Mature pilin is assembled with the help of TraQ and TraX (By similarity).
What are the official names of this protein?
Pilin.
What is the protein family that this protein belongs to?
Belongs to the TraA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Secreted. Note=Propilin is directed to the inner membrane, where it is cleaved and acetylated. Mature pilin forms filaments that are secreted to form the conjugative pilus (By similarity).
Protein: HRTA_STAAN
Sequence: MALVVKDIVKNFGEGLSETKVLKGINFEVEQGEFVILNGASGSGKTTLLTILGGLLSQTSGTVLYNDAPLFDKQHRPSDLRLEDIGFIFQSSHLVPYLKVIEQLTLVGQEAGMTKQQSSTRAIQLLKNIGLEDRLNVYPHQLSGGEKQRVAIMRAFMNNPKIILADEPTASLDADRATKVVEMIRQQIKEQQMIGIMITHDRRLFEYADRVIELEDGKITD
What is the function of this protein?
Part of the ABC transporter complex hrt involved in hemin import.  Responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Putative hemin import ATP-binding protein HrtA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. HrtA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ABIL1_ORYSJ
Sequence: MQQQQAWAAGLGGLAVAGVGEEGGGGGPAPTTVDEASMERSKSFVKALQELKNLRPQLYSASEYCEKSYLHSEQKQMVLDNLKDYAVRALVNAVDHLGTVAYKLTDLYEQQASEVSTLELKVACLNQQVLTCQTYTDKEGIRQQQMTGTATRHHKHYIVPTLANKRMQAFSEMQTDADIDSRPRPYPSAKTLFWHLASEKNSKTNGARQSEFVLEETKATKPASRGKEPSTSPLPKHLQTNLASSDFAMHNVGMKDQPGVRHLSSFSSFDNPRGRQIQKAPLRTKSMLAAFFVKHKSGKMKNVSVR
What is the function of this protein?
Involved in regulation of actin and microtubule organization.  Part of a WAVE complex that activates the Arp2/3 complex (By similarity).
What are the official names of this protein?
Probable protein ABIL1, Abl interactor-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the ABI family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: ILVC_RHOPT
Sequence: MRVYYDRDADLNLIKGKKVAVIGYGSQGHAHALNLKDSGVKDVAIALRKGSASAKKAENAGFKVMEVAEAAKWADVMMMLTPDELQADIYREHLHDNMKQGAALLFAHGLNVHFNLIEPRADLDVLMVAPKGPGHTVRSEYQRGGGVPCLIAIHKDASGNAHDLGLSYASAIGGGRAGIIETTFREECETDLFGEQVVLCGGLVELIKAGFETLVEAGYAPEMAYFECLHEVKLIVDLIYEGGIANMNYSISNTAEYGEYVTGPRIVTPETKAEMKRVLADIQNGIFTRNWMLENKVNQTSFKATRAKLAQHPIEEVGAKLRDMMPWIKKGALVDKSKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: RPC3_SCHPO
Sequence: MSQYAVELCEILVEEFFGDCCSAVASALLRHGRLTIPMLQKRTSLPGPKIRQALVSLMQHHMVLYVTVIENVREVTYYETQWKEIYNILRKGKDVYLISQKLNQEAASVVKYLSTQGRARVLEVFNAFDKKVDGSDEESRMMQKNLTELIYQKFLLVVQPRHLIPVGDQEMQLRIKHLDRRKSENVSEIKKNREVDDSVALEMLELRAADMSELQGLTRKPKESIPHPTKRRKRAVGSAPSVSTDLNNILDDDNSILVPDLSAHVRINSGKLSVLSKNARLTHWVERRIGKSTSLVYSHVLSMLEPRLFSISNQSPVFTLTTMELTRNFPNDIDVESSIVDKQYSVNSASNELRVMEKLNELDELAEEDNYEESVDENANRKSKVLAQHLELLADCSLKFISKIGNRGMGEWAVNFTHLTDMLRAIEYENFIEQKFGERAIRLLRIIKDKGKIEEKQLANIALLRQRDLRTVLQAMAEIGALELQEVPRSSDRAPSKTFFLWFHRPDRAYSLLLDELYHVIARLYMRLRDARAQRAQLIEKAERIDIKGNEEQYLQKFEQAELKKLYSYEEKLLLQASRLDDMVLVFRDNL
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase III subunit rpc3, RNA polymerase III subunit C3, RNA polymerase III subunit C82.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GATC_DESVV
Sequence: MKISKEQVATIARLARLDLDEARLERFAGQFGDILDYMDMLGAVDTTDVEPLYSPSEHGTVLRADEVHTHCTREELLANAPESDGQFFVVPRIV
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: PDRP2_LISMO
Sequence: MENPVIIYVISDAIGETAQHIIRAVTAQFSLNKPADIRRHAFIRDESALLETLEEAKATDGIVVQTLVQAKLAEYATNFCVQNNIPNVDLLHTLTAAVEAKTGLKSKQDPGNMRRLDSNYFDRIAAIEFAVKYDDCKDPRGLLDADIVLVGVSRTSKTPLSSFLANQNWKVANVPLVPEIPIPAELFQIPAERIIGLTTTPEKLAQIRKVRLRSIGLDEASSYSSEKRILEELEYGYDTFKKLGCQVIHVEDKAIEETAALITEIITSYH
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein 2, PPDK regulatory protein 2.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: EFG_PSYWF
Sequence: MARATPLNRYRNIGISAHIDAGKTTTTERILFYTGVSHKIGETHEGSATMDWMEQEQERGITITSAATTCFWSGMGQQFPQHRINIIDTPGHVDFTIEVERSMRVLDGACMVYCAVGGVQPQSETVWRQANKYKVPRLAFVNKMDRVGADFYRVKEQVKTRLGGNPVAMVIPIGKEDDFEGVIDLITMKAIYWDVESLGMKFEEREIPEELQEKAEEYRSELVEVAAEANEDLMNKYLEGEELTEDEIHAAIRQRTINNEIIPMYCGTAFKNKGVQKMLDAVIQYMPAPQDVPAIKGILDDKAETEGTREASDDAPFAALAFKIMNDKFVGNLTFVRVYSGVIKQGESVYNPVKMKRERIGRIVQMHADSQQELDEIRAGDIAALVGMKDVGTGDTLCDEKEIITLERMEFPEPVISLAVEPKTKADQEKMSIALGRLAKEDPSFRVHTDEESGQTIISGMGELHLEILVDRMKREFKVEANIGAPQVAYRETIRGTVEQEGKFVRQTGGRGKFGHVWLKLEPLDLDSGVDYQFEEQVVGGVVPKEYHGAVDKGIQERMKNGILAGYPIVGVKATLYDGSYHDVDSDELSFKMAGSIAFKKGFMNANPVLLEPVMKVEVETPEEYMGDIMGDLNRRRGMVQGMDDLPGGTKQIRAEVPLAEMFGYATNVRSMSQGRATYSMEFQKYAETPKSVAEEIMKKFSGKDDDEE
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURO_METM6
Sequence: MYIGRFLVLGKTEEGYPFVTYRVSSRSFPNRVAKVMDDNTVAILPKELEEMFKNPYITYNCVKLVGDVAVATNGSHTDIIADKIKLGLPIRDALSYSLLTMDYEKDDYNTPRIAVVLTKDSAYMGYVTDSDVRIKKVELEAGKAYYLAVYEACNITKHQEISVTGKTAEEVTKFVMDYEKFEKPVTAATVLVKDGFKLATL
What is the function of this protein?
Catalyzes the cyclization of 5-formylamidoimidazole-4-carboxamide ribonucleotide to IMP.
What are the official names of this protein?
IMP cyclohydrolase, IMP synthase, Inosinicase.
What is the protein family that this protein belongs to?
Belongs to the archaeal IMP cyclohydrolase family.
Protein: HEMA_I66A2
Sequence: MNTQILILATSAFLCVRADKICLGRHAVSNGTKVDTLTEKGIEVVNATETVEQKNIPKICSKGKQTIDLGQCGLLGTTIGPPQCDQFLEFSANLIIERREGDDICYPGKFDNEETLRQILRKSGGIKKENMGFTYTGVRTNGETSACRRSRSSFYAEMKWLLSNTDNGVFPQMTKSYKNTKREPALIIWGIHHSGSTAEQTRLYGSGNKLITVWSSKYQQSFAPNPGPRPQINGQSGRIDFYWLMLDPNDTVTFSFNGAFIAPDRASFLRGKSLGIQSDAQLDNNCEGECYHIGGTIISNLPFQNINSRAIGKCPRYVKQKSLMLATGMKNVPENSTHKQLTHHMRKKRGLFGAIAGFIENGWEGLIDGWYGYRHQNAQGEGTAADYKSTQSAINQITGKLNRLIEKTNQQFELIDNEFNEIEKQIGNVINWTRDSIIEVWSYNAEFLVAVENQHTIDLTDSEMNKLYEKVRRQLRENAEEDGNGCFEIFHQCDNDCMASIRNNTYDHKKYRKEAIQNRIQIDAVKLSSGYKDIILWFSFGASCFLFLAIAMGLAFICIKNGNMRCTICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: MNMA_NEIMA
Sequence: MNTTANPSNIIVGLSGGVDSSVTAALLKQQGYQVRGVFMQNWEDDDNDEYCSIKQDSFDAIAVADIVGIDIDIVNFAAQYKDKVFAYFLQEYSAGRTPNPDVLCNAEIKFKCFLDYAVGQGADTIATGHYARKEVRNGVHYLLKGLDQNKDQSYFLYRLKPFQLERAIFPLGGLEKPEVRRLAAEFNLPTAAKKDSTGICFIGERPFREFLQKYLPTDNGKMVTPEGKTVGEHVGLMFYTLGQRKGLGIGGGGEPWFVAAKDLTKNELMVVQGHDHPLLYTRSLVMNDLSFTLPERPKEGHYTCKTRYRMADAPCELRYLDDETVELVFDEPQWAVTPGQSAVLYDGDICLGGGIIQSTDKPVIITR
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPN2_PIG
Sequence: MAGAAQTTAFGQAVIGPPGSGKTTYCLGMSEFLRALGRRVAVVNLDPANEGLPYECAVDVGELVGLSDVMDELQLGPNGGLLYCMEYLEANLDWLRAKLDPLRGHYFLFDCPGQVELCTHHGALRSIFSQMTQWDLRLTAVHLVDSHYCTDPAKFISVLCTSLATMLHVELPHVNLLSKMDLIEHYGKLAFNLDYYTEVLDLSYLLDHLASDPFFRHYRQLNEKLVQLIEDYSLVSFIPLNIQDKESIQRVLQAVDKANGYCFGVQEQRSLEAMMSAAVGADFHFSSTLGLQEKYLAPSDQPVEQEAMQL
What is the function of this protein?
Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII).  May act at an RNAP assembly step prior to nuclear import.
What are the official names of this protein?
GPN-loop GTPase 2, ATP-binding domain 1 family member B.
What is the protein family that this protein belongs to?
Belongs to the GPN-loop GTPase family.
Protein: ATPE_MYCLE
Sequence: MDELNIEIVAVDRKIWSGKGTFLFTRTTAGEIGILPRHIPMVAQLVDDNMVRIEREGEKDLRVAVDGGFLSVTEERVSILAESAEFDSEIDENAAKQDAESDDPRIAARGRARLRAVGAID
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: Y1348_BACC1
Sequence: MKLGIVIFPSKMIQDKANGLRKRYDPHYALVPPHITLKTPFETQDEQLESIVNELHTIASKTNPFALHVGKVGSFAPVNNVLYFKVEKTPELTFLNEEMHSGFFTQEREYAFVPHLTIGQGLSDAEHADVLGRLRMKDFYYEQPIDRFHLLYQLENGTWTVHETFRLGKGNN
What are the official names of this protein?
Putative phosphoesterase BCE_1348.
What is the protein family that this protein belongs to?
Belongs to the 2H phosphoesterase superfamily. YjcG family.
Protein: HEM4_RUMJO
Sequence: MEHGFVALVGAGPGDKGLITIRGAELLSQADVVVYDRLVSQEIIKMIPTTAEKIDVGKENKFHPVKQEEINHILLEKSLEGKKVIRLKGGDPFVFGRGGEELELLYENNIPFEVVPGVTSAVAALCYGGIPATHRDFCSSLHIITGHAREGGQLSIPFHELKELNGTIVFLMGDSSLSYLMNGLINAGMEKDMPAAIVENGTRPNQRKLVATVGTLEQKALEMEIKSPAIIAVGKVCSLSEKFSWFMKKPLFGTKILVTRPKESSGTLVEKLRQLGAEPVEYPCIEVVPIPQNEKLYHACENIREYGWILLTSKNGIQIFFDYLNSKGLDARVLANTKIGTVGSQTAKALKEVGLISDFTPEIFDGRHLALGIAERVGENEKVLICDAAIASDDIVNILRSNNIKFDRVPLYNTNYINENSNKVKKSIVHGELKYITFTSASTVEGFIASMKDIPLESLTAVCIGNKTAEAAKKYNLRYVVAEKSTIDSMIDKLLEIGGGNIYD
What is the function of this protein?
May catalyze sequential reactions to synthesize uroporphyrinogen III from hydroxymethylbilane (HMB) and then precorrin-2, which are intermediate compounds in both vitamin B12 and siroheme biosyntheses.
What are the official names of this protein?
Porphyrin biosynthesis protein HemD.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the uroporphyrinogen-III synthase family.
Protein: SL9A2_RABIT
Sequence: MESAGTGRSLRTPPPRLLLLLLLQVAGPAGALAETLLNAPKAMGTSSSPLSPASVVAPGTTAFEESRLPVFTLDYPHVQIPFEITLWILLASLAKIGFHLYHKLPTIVPESCLLIMVGLLLGGIIFGVDEKSPPAMKTDVFFLYLLPPIVLDAGYFMPTRPFFENLGTIFWYAVVGTLWNSIGIGVSLFGICQIEAFGLSDITLLQNLLFGSLISAVDPVAVLAVFENIHVNEQLYILVFGESLLNDAVTVVLYNLFKSFCQMKTIETIDVFAGIANFFVVGIGGVLIGIFLGFIAAFTTRFTHNIRVIEPLFVFLYSYLSYITAEMFHLSGIMAITACAMTMNKYVEENVSQKSYTTIKYFMKMLSSVSETLIFIFMGVSTVGKNHEWNWAFVCFTLAFCLIWRALGVFVLTRVINWFRTIPLTFKDQFIIAYGGLRGAICFALVFLLPAAVFPRKKLFITAAIVVIFFTVFILGITIRPLVEFLDVKRSNKKQQAVSEEIHCRFFDHVKTGIEDVCGHWGHNFWRDKFKKFDDKYLRKLLIRENQPKSSIVSLYKKLEIKHAIEMAETGMISTVPSFASLNDCREEKIRKLTPGEMDEIREILSRNLYQIRQRTLSYNRHNLTADTSERQAKEILIRRRHSLRESIRKDNSLNRERRASTSTSRYLSLPKNTKLPEKLQKRKNISNADGDSSDSEADAGTTVLNLQPRARRFLPEPFSKKASQAYKMEWKNEVDAGSGQGQPSPPAAPRSKEGGTQTPAVLRQPLLSKDQGREDSLTEGGRPKPPPRLVRRASEPGNRKSRLGSDKP
What is the function of this protein?
Plasma membrane Na(+)/H(+) antiporter.  Mediates the electroneutral exchange of intracellular H(+) ions for extracellular Na(+) (PubMed:7685025, PubMed:9612213).  Major apical Na(+)/H(+) exchanger in the base of the colonic crypt.  Controls in the colonic crypt intracellular pH (pHi) to direct colonic epithelial cell differentiation into the absorptive enterocyte lineage at the expense of the secretory lineage (By similarity).
What are the official names of this protein?
Sodium/hydrogen exchanger 2, Na(+)/H(+) exchanger 2, NHE-2, Solute carrier family 9 member 2.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ZAPB_HAEIG
Sequence: MSLEILDQLEEKIKQAVETIQLLQLEVEELKEKNAESQRNIENLQTENEQLKNEHRNWQEHIRSLLGKFDNV
What is the function of this protein?
Non-essential, abundant cell division factor that is required for proper Z-ring formation.  It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle.  Its recruitment to the Z-ring requires functional FtsA or ZipA.
What are the official names of this protein?
Cell division protein ZapB.
What is the protein family that this protein belongs to?
Belongs to the ZapB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the septum at mid- cell, in a FtsZ-like pattern.
Protein: FRI1_TOBAC
Sequence: MLLKAAPAFALLNTQGENLSPLFSSSKSFSPKNGNRFVVSASKATNHKPLTGVVFEPFEELKKELMLVPAVPDTSLCRQKYSDDCEAAINEQINVEYNNSYVYHAMFAYFDRDNVALKGLAKFFKESSLEEREHAEKLMEFQNKRGGRVKLLSICAPPTEFDHCEKGDALYAMELALCLEKLTNQRLLNLHAVASRSNDVHLADFLESEFLVEQVDAIKKISEYVAQLRRVGQGHGVWQFDQMLLNEGAAA
What is the function of this protein?
Stores iron in a soluble, non-toxic, readily available form.  Important for iron homeostasis.  Has ferroxidase activity.  Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation (By similarity).
What are the official names of this protein?
Ferritin-1, chloroplastic, NtFer1.
What is the protein family that this protein belongs to?
Belongs to the ferritin family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ACPS_VIBVU
Sequence: MAIVGLGTDIAEIERVEKALARSGVAFAERILSAQEMETFVSLKQQGRFLAKRFAAKEAASKALGTGIAHGVSFQDFTIKNDDNGKPYLQLAGRAAELAHQMGVCHTHLSLSDERHYAVATVIFES
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVC_ECODH
Sequence: MAIILGIDPGSRVTGYGVIRQVGRQLSYLGSGCIRTKVDDLPSRLKLIYAGVTEIITQFQPDYFAIEQVFMAKNADSALKLGQARGVAIVAAVNQELPVFEYAARQVKQTVVGIGSAEKSQVQHMVRTLLKLPANPQADAADALAIAITHCHVSQNAMQMSESRLNLARGRLR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: YEAL_ECO57
Sequence: MFDVTLLILLGLAALGFISHNTTVAVSILVLIIVRVTPLSTFFPWIEKQGLSIGIIILTIGVMAPIASGTLPPSTLIHSFLNWKSLVAIAVGVIVSWLGGRGVTLMGSQPQLVAGLLVGTVLGVALFRGVPVGPLIATGLVSLIVGKQ
What are the official names of this protein?
UPF0756 membrane protein YeaL.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.