PharMolix/UniProtQA huggingface dataset:
Protein: FIME_PORG3
Sequence: MKSKSIIAQLLYVLIAFMAVSCVADKSEPCPSGEPTRVSGSIVSLEHHGLRGASADKENSVERLELWVFDEDGHFLERAVADLSGSTFTAKIIPSEVERRIHFIANYELADPSVWVGRSEREMLPSISVADDLETIRMWARISYPSIAPNQNLGQIQLLRNMAKFSLSVTPPAESKLYDASYALYNSWNKGTLAPFDPNTGSFPQGQITEPAGVVFANPTSEAAFKEADGAHFFYGFERDQSNIGTGAGITCLILKARYNLPNADYTYYKLDFVDTNKVRYNITRNHFYKMILKKAKAPGRPTLQEALDGAAANNIFLSAEVQALPAFSDGSGMLTVDHTYMVFVQGEPSGTFQATYIPQGQNNPDYSKLTVSVSTPTGQQAAVTSAQHEGNGKIKLTLAQQENLTKRSDVVIGVQGNPDLKRSVTVLVREKYQYVFFKANTSSAENNQVTTQISAGQGNELLISAKLPDVLNAALLPITFKVYTEHFYPKTGGMILGIEGGKTLYKYVLTTMPQNKELQFRFKSNKVNSAENIAVKMDYFHDQTIHVTN
What is the function of this protein?
Probably a component of the fimbrium tip; required for incorporation of FimC and FimD into fimbriae (PubMed:17526848, PubMed:19506009).  These long, filamentous pili are attached to the cell surface; they mediate biofilm formation, adhesion onto host cells and onto other bacteria that are part of the oral microbiome (PubMed:17526848, PubMed:19506009).  They play an important role in invasion of periodontal tissues and are major virulence factors (Probable).  FimC, FimD and FimE contribute to interaction with host CXCR4 and thereby down-regulate the TLR2-mediated host immune response (PubMed:19506009).
What are the official names of this protein?
Major fimbrium tip subunit FimE.
What is the protein family that this protein belongs to?
Belongs to the FimE family.
What are the subcellular locations of this protein?
Fimbrium. Cell outer membrane. Note=Probably synthesized as a palmitoylated precursor. Efficient export to the outer membrane and integration into fimbriae requires lipidation and subsequent proteolytic removal of the lipidated propeptide (Probable). Probably part of the fimbrium tip, as a part of the complex formed by FimC, FimD and FimE (PubMed:17675496).
Protein: HLDD_PARP8
Sequence: MTLIVTGAAGFIGSNLVKALNERGEDGIIAVDNLTRADKFKNLVDCEIDDYLDKTEFVERFARGDFGKVRAIFHEGACSDTMETDGRYMMDNNFRYSRAVLDACLAQGVQFLYASSAATYGGSTRFVEEREVEAPLNVYGYSKFLFDQVIRRVLPTAKSQIAGFRYFNVYGPRESHKARMASVAFHNFNQFRAEGKVKLFGEYNGYAAGEQTRDFVSVEDLVKVNLHFFDHPEKSGIFNLGSGRAQPFNDIASTVVNALRALDGEPALSLAELVQRGLIEYIPFPDALRGKYQCFTQADLTKLRAAGYDAPFLTVQEGVDRYVRWLSGQV
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: RK23_SOLLC
Sequence: MDGIKYAVFTDKSIRLLGKNQYTSNVESGSTRTEIKHWVELFFGVKVIAMNSHRLPGKSRRMGPIMGHTMHYRRMIITLQPGYSIPPLRKKRT
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L23, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ARNA_YERE8
Sequence: MKAIVFAYHDIGCVGLKALVEAGYDIQAVFTHTDSPNENRFFSSVARVAADLDLPVFAPEDVNHPLWIERIQQLQPDIIFSFYYRNMLCDDILSSAPRGGFNLHGSLLPKYRGRAPINWVLVNGETETGVTLHQMVKKADAGPIVGQHKVMISGSDTALTLHTKMRDAANELLRDLLPKMKNASLPLEPQKESEASCFGRRTADDGAIDWQKSALAINNLVRAVTEPYPGAFSYLGQRKLIIWRSQPLDVVHSKLAGTVLSTSPLVVACGDGALEIITGQGEEGLYVQGSRLAQEMGIVTGIRLGNKPSQKLKRRTRVLILGVNGFIGNHLTERLLRDNRYEVYGLDIGSDAICRFLDNPNFHFVEGDISIHSEWIEYHIKKCDVILPLVAIATPIEYTRNPLRVFELDFEENLKIVRDCVKYNKRIVFPSTSEVYGMCDDKEFDEDSSRLIVGPINKQRWIYSVSKQLLDRVIWAYGAKENLKFTLFRPFNWMGPRLDNLDAARIGSSRAITQLILNLVEGSPIKLVDGGEQKRCFTDIHDGIEALFRIIENRDGACDGQIINIGNPTNEASIRELAEMLLRCFEKHELRHNFPPFAGFKDIESSAYYGKGYQDVEYRTPSIRNARRILDWQPEIALEQTVMETLDFFLRGVVLEQNVLEQNVLEQNVLEQNVIEQSKTSKDEHHV
What is the function of this protein?
Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Bifunctional polymyxin resistance protein ArnA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
Protein: ATPD_STAAW
Sequence: MVKVANKYAKALFDVSLDTNNLETINEELTVINEAVKDKIEQLKMVDSNPTQTAEQRRELINGVFTDINPYIKNMMYVLADNRHISLIADVFKAFQSLYNGHYNQDFATIESTYELSQEELDKIVKLVTQQTKLSKVIVDTKINPDLIGGFRVKVGTTVLDGSVRNDLVQLQRKFRRVN
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GLPF_THEMA
Sequence: MSVYLAEFLGTMLLIILGDGVVANVVLKKSKGHNSGWIVITTGWGLAVAMSVYLVGRISGAHINPAVTIGLAFIGQFPWSKVPGYIFSQILGAFVGAILVYLTYLPHWKETDDPDAKLAVFCTGPAVRKYGANLLTEIIGTMVLLMGVLGIGANKLADGLNPLLVGFLVWSIGLSLGGPTGYAINPARDFGPRLAHAILPIPGKRDSDWSYSWVPIIGPIIGGILGASLYNWLF
What is the function of this protein?
Mediates glycerol diffusion across the cytoplasmic membrane via a pore-type mechanism.
What are the official names of this protein?
Probable glycerol uptake facilitator protein.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CINAL_THEP1
Sequence: MKKAAIITIGSELLEGLILNKNAQFLCQELKNLGYRVVKVSTVGDDLISISEEVKTLLLKVDLLILTGGLGPTQDDLTRDAVAKVLNRSLKLNEELLSKIKEKIKKYHSEIPQNIERQALVIDGAEVLDNPVGSAPGQLLTVDGKIVILLPGPPRELIPMFNALKDRLRTPDALYQVVLKYYSIPEAVLEDLLKDILYSQNIVEVATMADHVEGVRLRLTTHMKNKEYLDEMVKKILDKTGEHLYGVNDEKMEEVVVRLLKDRKKTLAVAESCTGGMLSSLVVNVPGASEVFAGGVVAYSNDLKKHILGVREDTLRKHGAVSKECVQEMTEGLKKLTGADICVSISGIAGPSGGTPEKPVGTVFIDIFEHEHITMRYNFTGDRNTIRTRSAMMALENLRKYLKGREKV
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: SURE_ESCF3
Sequence: MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINVPDLPLDQIKGIRVTRCGSRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPDTDFAAVDEGYVSITPLHVDLTAHNAQDVVSDWLNSVGVGTQW
What is the function of this protein?
Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP.  Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25).  Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.
What are the official names of this protein?
5'/3'-nucleotidase SurE, Exopolyphosphatase, Nucleoside monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPRT_SALA4
Sequence: MKTPRLPIAIQQAVMRRLRENLAQANLKLDRHYPEPKLVYTQRGTSAGTAWLESYEIRLNPVLLLENIDTFIAEVVPHELAHLLVWKHFGRKAPHGKEWKWMMESVLGVPARRTHQFALQSVRRNTFPYHCQCQQHQLTVRRHNRVVRGEAVYRCVHCGEPLVAG
What are the official names of this protein?
Protein SprT.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FDHD_ECOBW
Sequence: MKKTQRKEIENVTNITGVRQIELWRRDDLQHPRLDEVAEEVPVALVYNGISHVVMMASPKDLEYFALGFSLSEGIIESPRDIFGMDVVPSCNGLEVQIELSSRRFMGLKERRRALAGRTGCGVCGVEQLNDIGKPVQPLPFTQTFDLNKLDDALRHLNDFQPVGQLTGCTHAAAWMLPSGELVGGHEDVGRHVALDKLLGRRSQEGESWQQGAVLVSSRASYEMVQKSAMCGVEILFAVSAATTLAVEVAERCNLTLVGFCKPGRATVYTHPQRLSN
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity.  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
What are the official names of this protein?
Sulfur carrier protein FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF2_BRANA
Sequence: QKLCERPSGTWSGVCGNNNACKN
What is the function of this protein?
Possesses antifungal activity sensitive to inorganic cations.
What are the official names of this protein?
Defensin-like protein 2, Cysteine-rich antifungal protein 2, AFP2.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
Protein: PG055_VACCP
Sequence: MGFCIPSRSKMLKRGSRKSSSILARRPTPKKMNIVTDLENRLKKNSYIENTNQGNILMDSIFVSTMPVETLFGSYITDDYELKDLLNVTYNIKPDIVPDIKLDAVLDRDGNFRPADCFLVKLKHRDGFTKGALYLGHSAGFTATICLKNEGVSGLYIPGASVIRSNICQGDTVSRSSRGVQFLPQIGGEAIFLIVSLCPTKKLVETGFVIPEISSNDNAKIAARILSEKRKDTIAHIDTLIQHRQQLELAYYNSCMLTEFLHYCNSYAGTIKESLLKETIQKDINITHTNITTLLNETAKVIKLVKSLVDKEDTDIVNNFITKEIKTVEVLKQRQNS
What is the function of this protein?
Stimulates increases in peripheral microtubule dynamics and may increase the motility of the infected cells, contributing to cell-to-cell spread of the virus.  Seems to inhibit the signaling via the GTPase RHOA and DIAPH1/mDia.
What are the official names of this protein?
Protein OPG055, Protein F11, Protein F7.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG055 family.
Protein: MTNA_YERPB
Sequence: MQTLNTLDLQTTSLKIVNGQLWILDQQALPQRQEWLLADTVASLIEHIQALRVRGAPLIGLSASLLLALLAERGLSQALLEQALIALRESRPTAVNLMNNLARMQQALLQPNWVTAMAAEALRLVDEDRELCERIAQHGAALVKPGSNLLTHCNTGGLATAGIGTAIGVLLRAHQQGNLRQVWVDETRPLLQGGRLTAWELGELGIPYQLICDSMAASLMAHGQVDAIWVGADRIAANGDVANKIGTYSLAVLAHYHRIPFYVAAPHTTHDPDCPDGAAIPIEQRAASEVTGVSGGFGHCQWAPKDTAVYNPAFDVTPAALISGWVLDSGVITPEQVAAGFFQPHR
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: ADMB_TRIVH
Sequence: MKAFSCLLAVIATAASLFQHVDASHARDKLNNISRVERPVIHTPSRRVHAHSHFDLTFDLYPRRNRIKLQLEPNHDVLSHNARVTFLDTEGNVDRIERIERRDHSVFKGWAWTQAKSGVWERVGWARIIMHRDGEDPLFEGVFTVMHDHHQVIAKSKYVRKRHQQDPPLDNTPGEYMLLFRGSDIAQTQSTGNVERSIMSSPSCDADTLAYDSNSNFMFPPLPEENNTSIWNYFMTSIGKRQMTDTGGVVPGSRDLKETIGSTSGCPNTRKVALIGVVADCTYTNTFASEMDARADIISVVNAASVVYEHSFNISLTLGEINILPKNCPATASSATPFNQQCDDRAGGGSFTLADRLNTFSAWRGKKTDDFAFWTLMTDCTTENQVGLAWAAQLCVKGVQGNPDSRNSSSQAVAGANVVSKTDNTWQVFAHEAGHIFGAVHDCDSMLCQNPANPDNSRCCPATASTCDARGRFMMNPTSGSQITNFSPCSIGQICSRMARRTILTNCLTTNRGVDTISGQQCGNGIVEDGEDCDCGDEESCKGNTCCDPKTCKYTSGSQCDDANEECCKGCKFASSSTICRTSSGPCDPEEKCSGNSGDCPHDIHSKDGGTCGTDLQCASGQCTSRDLQCQMHLGNQVAGSRTVAFDSYGCEVACKDPDRPNVRYEGSLTFLDGTPCGGGGTCKNGQCSGSTFGNEVSDWVSRHKPIVIGVAVGAGCLLLLAIASCICGRSRRQRPRNRKMPPINMRPMAPAYNGWNGAPPNAQQSSPGGHPPYNNIPPPINAPPPAYPGHMPPTRYA
What is the function of this protein?
Probable zinc protease.
What are the official names of this protein?
Disintegrin and metalloproteinase domain-containing protein B, ADAM B.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RS14_ALISL
Sequence: MAKQSMKAREAKRAKLVTKFAEKRAALKVLISDVNASEEDRWNAVLKLQSLPRDSSASRQRNRCNQTGRPHGYLRKFGLSRIKVREACMKGEIPGLRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: PLAS_SYNJB
Sequence: MSLVFNLVKRLQLILLSLVVGGLAVAFLSNPAAAETYIVKMGSDKAQLVYDPPSLTINQGDTVQWVNNKVYPHNVVFDKVPGGDAALAAKLSHKALLTAPKQVVESAFVDVPPGEYTYYCTPHRGAGMVGKIIVNG
What is the function of this protein?
Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I.
What are the official names of this protein?
Plastocyanin.
What is the protein family that this protein belongs to?
Belongs to the plastocyanin family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Lumenal side. Note=Loosely bound to the thylakoid inner membrane surface.
Protein: NS1_I72A6
Sequence: MDSNTITSFQVDCYLWHIRKLLSMRDMCDAPFDDRLRRDQKALKGRGSTLGLDLRVATMEGKKIVEDILKSETDENLKIAIASSPAPRYITDMSIEEISREWYMLMPRQKITGGLMVKMDQAIMDKRIILKANFSVLFDQLETLVSLRAFTEDGAIVAEISPIPSMPGHSTEDVKNAIGILIGGLEWNDNSIRASENIQRFAWGIRDEDGGPPLPPKQKRYMARRVESEV
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: CCD62_HUMAN
Sequence: MNPPAAFLAGRQNIGSEVEISTIEKQRKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEERCSKLEGELHKRTEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSEDLEARNETLSNTLVELSAQVGQLQAREQALTTMIKLKDKDIIEAVNHIADCSGKFKMLEHALRDAKMAETCIVKEKQDYKQKLKALKIEVNKLKEDLNEKTTENNEQREEIIRLKQEKSCLHDELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIYVKQQSDLQFLNFNVENSQELIQMYDSKMEESKALDSSRDMCLSDLENNHPKVDIKREKNQKSLFKDQKFEAMLVQQNRSDKSSCDECKEKKQQIDTVFGEKSVITLSSIFTKDLVEKHNLPWSLGGKTQIEPENKITLCKIHTKSPKCHGTGVQNEGKQPSETPTLSDEKQWHDVSVYLGLTNCPSSKHPEKLDVECQDQMERSEISCCQKNEACLGESGMCDSKCCHPSNFIIEAPGHMSDVEWMSIFKPSKMQRIVRLKSGCTCSESICGTQHDSPASELIAIQDSHSLGSSKSALREDETESSSNKKNSPTSLLIYKDAPAFNEKASIVLPSQDDFSPTSKLQRLLAESRQMVTDLELSTLLPISHENLTGSATNKSEVPEESAQKNTFVSY
What is the function of this protein?
Nuclear receptor coactivator that can enhance preferentially estrogen receptors ESR1 and ESR2 transactivation.  Modulates also progesterone/PGR, glucocorticoid/NR3C1 and androgen/AR receptors transactivation, although at lower level; little effect on vitamin D receptor/VDR.  Required for normal spermiogenesis.  It probably plays a role in acrosome formation (By similarity).
What are the official names of this protein?
Coiled-coil domain-containing protein 62, Protein TSP-NY, Protein aaa.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Mainly nuclear.
Protein: QUEF_NOVAD
Sequence: MPSGAFRCRSGHKAVVMANTPLFLGQNSSLPASPDEAVLDYVANPRPGALYMIRFAAPEFTSLCPVTGQPDFAHLVIDYAPGECIVESKALKLFLGSFRNHAGFHEDVTVGIGQRLFDEMKPQWLRIGGYWYPRGGIPIDVFWQSGPPPAGLWLPDQGVAPYRGRG
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_EHRCR
Sequence: MSGLASKAKSRVKSSKGKNSTNIHADELNEDVGVVVRVMTAVVDVKFASGKIPKILNALESKEIYNGKKLVLEVSQHISDSIVRCIALDGTDGLSRNDKFIDTGAPISVPVGRGTLGRVFDVLGNTIDECGPLEESSYFIKQIYSEIPKLTDQKIATEILVTGIKVIDLLAPYLKGGKVGLFGGAGVGKTVLIMELIHNIAKAHKGVSVFAGVGERTREGNDLYHEMIESGVINLENKDQSQAVLVYGQMNEPPGARLRVALSALTMAEYFRDAENQDVLFFVDNIFRFTQSGSEISALLGRIPSAVGYQPTLAAEMGAMQERITSTNSGSITSVQAIYVPADDLTDPAPATSFAHLDSTTVLSRQISELGIYPAVDPLDSTSQALSADVVGKEHYDVAKEVQRILQTYKSLQDIIAILGMDELSEEDKLIVARARKIQRFLSQPFHVAEVFTGAPGKFVSLEDTVLSFKGLVEGKYDHLPEAAFYMVGSIDDVIKKAELLQKEGKV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RISB_BURMA
Sequence: MEIGQYQPNLEGDGLRIGIVQSRFNEPVCNGLADACVEELERLGVSGEDVLLVTVPGALEIPLALQKLAESNQFDALIALGAVIRGETYHFELVSNESGAGITRIALDFNTPIANAVLTTETDEQAIARMTEKGRDAARVAVEMANLTMTLDQLSDDEEDEEDEDDEDEEERA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: LANA_RUMGN
Sequence: MRNDVLTLTNPMEEKELEQILGGGNGVLKTISHECNMNTWQFLFTCC
What is the function of this protein?
Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria.  The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores.  Ruminococcin A is a broad spectrum bacteriocin exhibiting activity against a wide range of pathogenic clostridia and B. longum.
What are the official names of this protein?
Ruminococcin-A, RumA protein 1/2/3.
What is the protein family that this protein belongs to?
Belongs to the type A lantibiotic family.
What are the subcellular locations of this protein?
Secreted.
Protein: DCXR_CAEEL
Sequence: MPANYDFTDKRILVTGASQGIGKEICLSLAKAGAQVIAFARNEANLLSLVKETTSLRYTIIPIVGDVSANEEVLFKLIVPHFPIHGLVNNAGIATNHAIGQITQQSIDRTFAVNVRGPILIAQLVARNFVDRQIKGSIVNISSQAAIRPLDNHTVYCASKAALDMVTRCLANELGSQNIRVNSVNPTVVMTDMGRDNWSDPDKKKKMLDRMPIKRFAEVDEVVNAVLFLLSDNASMTTGSTLPVDGGFSNN
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-xylulose, D-xylulose, L-(+) erythrulose, D-erythrose, D-threose, L-ribulose, 1,4-dibromo-2,3-butanedione and 2,3-heptanedione (PubMed:21477590).  Also active against isatin, 9,10-phenanthrenequinone, menadione, 2,3-hexaenadione and 3,4-hexahenadione (PubMed:21300042).  No activity observed when tested using NADH rather than NADPH (PubMed:21300042).
What are the official names of this protein?
L-xylulose reductase, XR, Dicarbonyl/L-xylulose reductase, DCXR, Short-chain dehydrogenase 21.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Cell membrane. Note=Detected on the cell membrane of spermatids.
Protein: MCSB_STAAC
Sequence: MTHNIHDNISQWMKSNEETPIVMSSRIRLARNLENHVHPLMYATENDGFRVINEVQDALPNFELMRLDQMDQQSKMKMVAKHLISPELIKQPAAAVLVNDDESLSVMINEEDHIRIQAMGTDTTLQALYNQASSIDDELDRSLDISYDEQLGYLTTCPTNIGTGMRASVMLHLPGLSIMKRMTRIAQTINRFGYTIRGIYGEGSQVYGHTYQVSNQLTLGKSELEIIETLTEVVNQIIHEEKQIRQKLDTYNQLETQDRVFRSLGILQNCRMITMEEASYRLSEVKLGIDLNYIELQNFKFNELMVAIQSPFLLDEEDDKSVKEKRADILREHIK
What is the function of this protein?
Catalyzes the specific phosphorylation of arginine residues in proteins.
What are the official names of this protein?
Protein-arginine kinase.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.
Protein: PDXH_RHORT
Sequence: MSSLEDRDPYALFAEWLEEAGTTEPNDPNAMALATCTPEGRPSLRMVLLKGVIAQADAEGGFIFYTNLESRKGGELLANPHAALCFHWKSLRRQVRVEGPVVAVSDAEADAYFASRHRDSRIGAWASMQSRPLQGRFELERRVAQFAARYAVGAVPRPPHWSGFRVVPEVIEFWHDRPFRLHDRVVYRSEGSGWTHSRLYP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: RS8_MYCLE
Sequence: MTMTDPIADFLTRLRNANSAYHDEVTVPHSNIKANIAQILKNEGYIRDFRTEDARVGKSLIIQLKYGPSRERSIAGLRRVSKPGLRVYAKSINLPRVLGGLGVVIISTSSGLLTDRQAARQGVGGEVLAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RPPH_SALHS
Sequence: MIDDDGYRPNVGIVICNRQGQVMWARRFGQHSWQFPQGGINPGESAEQAMYRELFEEVGLSRKDVRILASTRNWLRYKLPKRLVRWDTKPVCIGQKQKWFLLQLMSADAEINMQTSSTPEFDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFASVVMALQDNPPKLQSAPAYRRKRG
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: HFQ_PSEA6
Sequence: MAKGQSLQDPFLNALRKERIPVSIYLVNGIKLQGQVESFDQFVILLKNTVSQMVYKHAISTVVPSRALPVAATNPHADADENQ
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: RL4_BOVIN
Sequence: MACARPLISVYSEKGESSGKNVTLPAVFKAPIRPDIVNFVHTNLRKNNRQPYAVSELAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRRVNTTQKRYAICSALAASALPALVMSKGHRIEEVPELPLVVEDKVEGYKKTKEAVLLLKKLKAWNDIKKVYASQRMRAGKGKMRNRRRIQRRGPCIIYNEDNGIIKAFRNIPGITLLNVSKLNILKLAPGGHVGRFCIWTESAFRKLDELYGTWRKAASLKSNYNLPMHKMLNTDLSRILKSPEIQRALRAPRKKIHRRVLKKNPLKNLRIMLKLNPYAKTMRRNTILRQARNHKIRMDKAAAALEAKSDQKGVQGKKPVVGNKEKKAVGDKKLKKPVVGKKAAGTKKPAAEKKPTEKKPTSEEKKAAA
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
What are the subcellular locations of this protein?
Cytoplasm.