PharMolix/UniProtQA huggingface dataset:
Protein: ENO_HELPH
Sequence: MLTIKDIHALEVMDSRGNPTIQASVILSDNTKASAIVPSGASTGKREALELRDNDKTRFLGKGVLRACENVNSVIKHHLIGLEAINQAFVDERLRALDGTPNYANLGANAVLGVSMALARASAKALNLPLYRYLGGANALTLPVPMLNIINGGTHANNSIDFQEYMIMPLGFESFREALRASTEVYHTLKKLLDGKNQLTSVGDEGGFAPNFSNNVEPLEAISQAIEKAGYKLGEEIALALDVASSELVDENFNYHLKGENKILDSHELVAYYKELVAKYPIVSIEDGLSEDDWEGWAFLSKELGRQIQLVGDDLFVTNASILQKGIEKNIANAILIKPNQIGTISETLETIRLAKHHAYQCVMSHRSGESEDSFIADFAVALNAGEIKTGSTARSERIAKYNRLLEIEHELKGGIYIGKELFKHG
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: MA1C1_HUMAN
Sequence: MLMRKVPGFVPASPWGLRLPQKFLFLLFLSGLVTLCFGALFLLPHSSRLKRLFLAPRTQQPGLEVVAEIAGHAPAREQEPPPNPAPAAPAPGEDDPSSWASPRRRKGGLRRTRPTGPREEATAARGNSIPASRPGDEGVPFRFDFNAFRSRLRHPVLGTRADESQEPQSQVRAQREKIKEMMQFAWQSYKRYAMGKNELRPLTKDGYEGNMFGGLSGATVIDSLDTLYLMELKEEFQEAKAWVGESFHLNVSGEASLFEVNIRYIGGLLSAFYLTGEEVFRIKAIRLGEKLLPAFNTPTGIPKGVVSFKSGNWGWATAGSSSILAEFGSLHLEFLHLTELSGNQVFAEKVRNIRKVLRKIEKPFGLYPNFLSPVSGNWVQHHVSVGGLGDSFYEYLIKSWLMSGKTDMEAKNMYYEALEAIETYLLNVSPGGLTYIAEWRGGILDHKMGHLACFSGGMIALGAEDAKEEKRAHYRELAAQITKTCHESYARSDTKLGPEAFWFNSGREAVATQLSESYYILRPEVVESYMYLWRQTHNPIYREWGWEVVLALEKYCRTEAGFSGIQDVYSSTPNHDNKQQSFFLAETLKYLYLLFSEDDLLSLEDWVFNTEAHPLPVNHSDSSGRAWGRH
What is the function of this protein?
Involved in the maturation of Asn-linked oligosaccharides.  Trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce first Man(8)GlcNAc(2) then Man(6)GlcNAc and a small amount of Man(5)GlcNAc.
What are the official names of this protein?
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IC, HMIC, Mannosidase alpha class 1C member 1, Processing alpha-1,2-mannosidase IC, Alpha-1,2-mannosidase IC.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 47 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: AAEB_PANAM
Sequence: MTEFLRFPIKLTFALVAALMIGFHLNLETPRWAVMTAGIVAGGTAFAAGGDPYSGALRYRGILRIIGTFIGCVAALVIMIATVRAPVVMLLLCCIWAGFCVWLSSLIKVENSYALGLAGYTALIIVVTANASGGLTLVPQYAVERCSEIILGILCAILADMIFSPRSIKKVIDAEVDSLLVAHYRLLQLCVAHEDKEEVDKAWGALVRRTTALSSMRSQLMMESSRWQNTSRRLQMLNTLSLTMITQAAETFLIQNSRPDYIATQYRVLMEKEAATAEDVHKRMKALRRLIAVSSKTVPETLESWVEAATEYQLLTHGIKSNGRITALEEGILQREVVIQARSAENHHAMINGVRTFVATALGSLFWLYTGWTSGSGCMVMLGVITALAMRMPNPLMMAKDFVYGMTVAVPLGALYFMYILPNTQQSAVLLCIAIGLLGFISGILIQRRQIGTLGAMVGTINVLVLDNPMQFNFTQFIDNALGQWIGSFVALMVILLIRDKSKARTGRKLLNRFMYAAVSAMTTNQARRRENHLPALYQQLFLLLNLFPGDIDKYRIALTLIIGHQRLRAADVPVNADLSAYHRQLRHTADRIISVRSDEKRRYYFERLLKELDVYQHKLAHYDAPTSVTEPVTRLAEMLKKYQNTLVQI
What is the function of this protein?
Forms an efflux pump with AaeA.  Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeB, pHBA efflux pump protein B.
What is the protein family that this protein belongs to?
Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LDCI_ECOLI
Sequence: MNVIAILNHMGVYFKEEPIRELHRALERLNFQIVYPNDRDDLLKLIENNARLCGVIFDWDKYNLELCEEISKMNENLPLYAFANTYSTLDVSLNDLRLQISFFEYALGAAEDIANKIKQTTDEYINTILPPLTKALFKYVREGKYTFCTPGHMGGTAFQKSPVGSLFYDFFGPNTMKSDISISVSELGSLLDHSGPHKEAEQYIARVFNADRSYMVTNGTSTANKIVGMYSAPAGSTILIDRNCHKSLTHLMMMSDVTPIYFRPTRNAYGILGGIPQSEFQHATIAKRVKETPNATWPVHAVITNSTYDGLLYNTDFIKKTLDVKSIHFDSAWVPYTNFSPIYEGKCGMSGGRVEGKVIYETQSTHKLLAAFSQASMIHVKGDVNEETFNEAYMMHTTTSPHYGIVASTETAAAMMKGNAGKRLINGSIERAIKFRKEIKRLRTESDGWFFDVWQPDHIDTTECWPLRSDSTWHGFKNIDNEHMYLDPIKVTLLTPGMEKDGTMSDFGIPASIVAKYLDEHGIVVEKTGPYNLLFLFSIGIDKTKALSLLRALTDFKRAFDLNLRVKNMLPSLYREDPEFYENMRIQELAQNIHKLIVHHNLPDLMYRAFEVLPTMVMTPYAAFQKELHGMTEEVYLDEMVGRINANMILPYPPGVPLVMPGEMITEESRPVLEFLQMLCEIGAHYPGFETDIHGAYRQADGRYTVKVLKEESKK
What is the function of this protein?
Inducible lysine decarboxylase that catalyzes the proton-dependent decarboxylation of L-lysine to produce the polyamine cadaverine and carbon dioxide (PubMed:4590109).  Plays a role in pH homeostasis by consuming protons and neutralizing the acidic by-products of carbohydrate fermentation (PubMed:17209032).
What are the official names of this protein?
Inducible lysine decarboxylase, LDCI.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-I family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTD_MYCMM
Sequence: MRVLVQRVCSAAVTVDGDVVGAVRPPGQGLLAFVGVTHGDDGDKARRLAEKLWYLRILTDEKSASDLGAPILVVSQFTLYADTVKGRRPSWNAAAPRAVAEPLVAAFAEALRALGAHVEAGVFGAHMQVELINDGPVTVMLEL
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABHL_CAMJE
Sequence: MKTRFDKAKISGICVSVPEHKICIDDELESVFSNDIKTLKRMKKVIGLNTRYICDENTCVSDLGKHAANTLLQGLNIDKNSLDALIVVTQSPDFFMPSTACYLHQLLNLSSKTVAFDLGQACAGYLYGLFVAHSLIQSGLGKILLICGDTLSKFIHPKNMNLAPIFGDGVSATLIEKTDFNEAFFELGSDGKYFDKLIIPKGAMRIPKADIFNDDSLMQTEEFRQLENLYMDGANIFNMALECEPKSFKEILEFSKVDEKDIAFHLFHQSNAYLVDCIKEELKLNDDKVPNFIMEKYANLSACSLPTLLCELDTPKEFKASLSAFGAGLSWGSAVLNFKDLYTKNILIYTKEK
What is the function of this protein?
May catalyze the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
What are the official names of this protein?
Putative 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSH_XANCB
Sequence: MTALPATSIAAPSLDDLDALNAHLETLRADERVAWALQHGPQQAALSSSFGAQSAVTLHLLTQQRPDIPVILIDTGYLFPETYRFADALTERLSLNLQVYRPLVSRAWMEARHGRLWEQGMVGIDQYNNLRKVEPMRRALDELNVGTWFTGLRRSQSGGRAQTPIVQKRGDRYKISPIADWTDRDVWQYLQAHALPYHPLWEQGYVSIGDFHTTRRWEPGMREEDTRFFGLKRECGIHEDI
What is the function of this protein?
Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
What are the official names of this protein?
Phosphoadenosine 5'-phosphosulfate reductase, PAPS reductase, 3'-phosphoadenylylsulfate reductase, PAPS reductase, thioredoxin dependent, PAPS sulfotransferase, PAdoPS reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OMPB_NEILA
Sequence: MKKSLIALTLAALPVAAMADVTLYGTIKAGVETYRTVKHTDGKVTEVKTGSEIADFGSKIGFKGQEDFGNGLKAIWQLEQSASIAGTNSGWGNKQSFIGLKGGFGTVRAGNLNSILKSTGDNVNAWESGKATEDVLQVSKISAPEHRYASVRYDSPEFAGFSGSVQYAPKDNSGANGESYHVGLNYQNSGFFAQYAGLFQRHGEGTKATVGEPVEKLQVHRLVGGYDNDALYASVAVQQQDAKLAAAPNSHNSQTEVAATVAYRFGNVTPRVSYAHGFKGTVAKADGDNRYDQVVVGAEYDFSKRTSALVSAGWLQEGKGAGKTVSTASTVGLRHKF
What is the function of this protein?
Serves as a slightly cation selective porin.
What are the official names of this protein?
Major outer membrane protein P.IB, PIB, Protein IB, Porin.
What is the protein family that this protein belongs to?
Belongs to the Gram-negative porin family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: GABAT_SCHPO
Sequence: MSSTATVTESTHFFPNEPQGPSIKTETIPGPKGKAAAEEMSKYHDISAVKFPVDYEKSIGNYLVDLDGNVLLDVYSQIATIPIGYNNPTLLKAAKSDEVATILMNRPALGNYPPKEWARVAYEGAIKYAPKGQKYVYFQMSGSDANEIAYKLAMLHHFNNKPRPTGDYTAEENESCLNNAAPGSPEVAVLSFRHSFHGRLFGSLSTTRSKPVHKLGMPAFPWPQADFPALKYPLEEHVEENAKEEQRCIDQVEQILTNHHCPVVACIIEPIQSEGGDNHASPDFFHKLQATLKKHDVKFIVDEVQTGVGSTGTLWAHEQWNLPYPPDMVTFSKKFQAAGIFYHDLALRPHAYQHFNTWMGDPFRAVQSRYILQEIQDKDLLNNVKSVGDFLYAGLEELARKHPGKINNLRGKGKGTFIAWDCESPAARDKFCADMRINGVNIGGCGVAAIRLRPMLVFQKHHAQILLKKIDELI
What is the function of this protein?
Required for the degradation of gamma-aminobutyric acid (GABA), which is important for utilization of GABA as nitrogen source.  Deaminates GABA to succinate-semialdehyde, which in turn is converted to succinate by the succinate semialdehyde dehydrogenase.  Cannot transaminate beta-alanine (BAL).
What are the official names of this protein?
4-aminobutyrate aminotransferase, GABA aminotransferase, GABA-AT, Gamma-amino-N-butyrate transaminase, GABA transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SQS1_PODAS
Sequence: MQSPTLLTFDLPPESRAMSVPFPQRRFSRVSRTQMVRFPDSALAWLQDLAHLTPTDFSLKDEVRNTQSHHLDSAWTSGTVKLRQKPVSFVSAGYSEPLKLLEDIEQDKVPPGEATESKADDMDITTVDVNLNVSAEAVIEKTTLVELDSAAKGKMVLSNSTSQDNPSSETPQEQAQDLFFFDVSGDKAIRDKHRAVHPPPLVPIRKPSLAESDSSEEVILFRGRAGNAKTVPQSNFVVRNGVATNTTTAITPTGDKTKPTAAEETSLRDDPEVIPVAREKRAGRQRSRSKASKIPKTDEDDEEDAILADYIANMSANPEDDFISDQLRSFNNRRDLGGDNFALNLGSGDENDMPVVEDLSGDEQQAESSGSGLSDADEDNGDENDEADEDDDMDADMDDEGLARLLAKQEELGLGSDELVLIPESFGVSKRGAKKGGQKRATPSSFAKSANASSVADAFDDLDLADWTVPVPRKRRSKQPPNFNISDSEIEAKLKLDWSRDRERKKERKLARESLRGQGLLDKNASPDDLRVKYPVGLRLEDFKTELVAFLISSDERLEFPPLDKHGRMVLHQLALKFNVKSQSTGKGTTRRPVLYRSKRTITFKPHQITEATRQVDGAARRVGRKYFPRADVAGPRGDTPRDGFRGSAHVSVKALVLREGEVVGASAPELGQENKGRAMLEKMGWSKGMALGALENKGILEPVAQVVKKSKAGLGRT
What is the function of this protein?
May be involved in splicing.
What are the official names of this protein?
Protein SQS1.
What is the protein family that this protein belongs to?
Belongs to the SQS1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: FAEHP_METB6
Sequence: MYLVGEALIGEGAELAHIDLLLGSKEGPVGSAFANAVSQLSMGHTPLLAVVRPNLLTKPATVIIPKVTLKDMEQVNEMFGPVQAAVAKAIADSLEEGAFKDIDIEGIAIIASAFVHPEAKDYNRIYRYNYGATKLALHRALDKFPDEKTLVYEKDRAAHGIMGFKVQRLWDPPYLQVAMDLVDMGKVAQVLKEVPQNDHVIIEAGTPLIKKFGLNVIGEIRKLRPNAFIIADMKILDTGNLEARMAADATADAVVVSGLAPTSTIEKAISEARKVGIYSIIDMLNVQNPAKLIEKLKVKPDIVELHRAIDTEETAHAWGDIPAMKKAAGGKLLVATAGGIRVEVVKDALKAGADILVVGRSITASKDIGHATDEFLDQLNREEIDQFRIMTDF
What is the function of this protein?
Catalyzes the reversible formation of ribulose-5-phosphate and formaldehyde from 3-hexulose-6-phosphate.
What are the official names of this protein?
Bifunctional enzyme Fae/Hps.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily.
Protein: NU5M_ANOAR
Sequence: MNYLVNYCKISFYFLMSISLSLFLISLKFLLMDLVYFIEWEILSLQSMSIVMTFLFDWMSLMFMSFVLLISSLVIFYSNQYMEEDYNINRFILLVLMFVMSMMMLIISPNLISILLGWDGLGLVSYCLVIYFQNVKSYNAGMLTALSNRIGDVALLLAIAWMLNYGSWNYIFYLDMMKNNIEMMIIGGLVMLAAMTKSAQIPFSSWLPAAMAAPTPVSALVHSSTLVTAGVYLLIRFNDVLMNWWMAQFLLLVSGLTMFMAGLGANFEFDLKKIIALSTLSQLGLMMSILSMGFYKLAFFHLLTHALFKALLFMCAGSIIHNMKNSQDIRMMGSLSMSMPLTCSCFNVANLALCGMPFLAGFYSKDLILEMVMLSYVNVFSFFL
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 5, NADH dehydrogenase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SYI_TROWT
Sequence: MCDQGEVSSQNSSDYKEQRPTPRPNLPKIEESVLAFWSSDKTFEASLEQRQHGKRWVFYDGPPFANGLPHFGHLLTGYIKDAIPRYQTMRGQYVPRVFGWDTHGLPAELEAMKRLGITEKSQIESMGIASFNEAARKSVLTYVDQWEEYVNRQARWVDFKNGYKTLDLDYMESVLWAFKTLYKKGVIYEGYKVLPYCWNDQTPLSNHELRMDDEVYKQRLDDSLTVTFPLIGQKAKTCGLDGVAALAWTTTPWTLPSNMALIVSPNVEYVVVSSARQNSNSDFLLCKSSLDSYAECLGYESGQDARASIRRTLLGKEIEGIHYKPLFDYYADLHNAFTILSDNYVDVTEGTGIVHASPAHGEDDKRVCDAFGVPTVVSINDAACFTDVISNYAGMHIFDANAVIRSDLSRDGRILRHESYKHSYPHCWRCRSPLIYKAVTSWFFRITDSVNRMLELNQQINWVPKSVKNGQFAKWLSSAKDWSISRTRYWGTPIPVWKSDNPEYPRIDCYGSLKELEDDFGIKLTDLHRPEIDRLTRPNPDDPTGASTMRRVPDVLDVWFDAASMPFAQLHYPFENIERFEANKSADFIVEYAGQIRGWFYLLHAMSTALFDGVAFKNAICHGIVLGDDGQKASKSLRNYPDVYDVFENEGSDAVRWYLISSSILRGGSLIVSRKKIQDAIRQYITPLWSSWYFFHIYSEAARPGGYKARFSVDSQDILDRYILSKTGLLVEDVTRFMDSFDMASAALQLRDFVAVLTNWYIRRSRDRFWDGSDTGAFDTLYTVLETLCRLGAVFVPMVSEHVYKCLTNSRSVHLSDWPDVATFPNETGLVETMDRVRKICSTGLSLRKRLGIKARQPLSSAHIRVAQVGSLAQYKDIISGELNVKTVSIEEGSCTQRMLKILPRVAGPRLAGDVQTVIAAARRGDWTDHDGHVTAGGIPLLENEYQLVAGAQDSKNSQPLPFGGSVTLDTRIDETLRSEGVARDTVRQIQIARKEKDLNITDRISLEVCVPDEQVKNNLLAFSELICKETLCDRLDILVKKGIDGITVSLEKFRQ
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURC_HELP2
Sequence: MLETPKVLLKNLQDCKIHFIGIGGIGISGLAKYLKAQGATISGSDIAISPSVKYLKALGVEINIPHDPKAINNQDVIIHSAIIKEDNTEIQRAKELEIPILSRKDALYSILKDKRVFSVCGAHGKSSITAMLSAICPAFGAIIGAHSKEFDSNVRESANDSLVFEADESDSSFLFSNPFCAIVPNTEPEHLEHYDHDLERFFFAYEYFLDHAQKRVIYKEDPFLKNYSKDAIVLEKKDIYNIQYILKDGEPYTSFELKDLGAFLVWGLGEHNATNASLAILSALDELNLEEIRNNLLNFKGIKKRFDILQKNALILIDDYAHHPTEISATLKSARIYADLLDTQEKIVVIWQAHKYSRLMDNLEEFKKCFLEHCDRLIILPVYSASEVKRDIDLKAHFKHYNPTFIDRVRKKGDFLELLVNDNVVETIEKGFVIGFGAGDITYQLRGEM
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DLDH_SHIFL
Sequence: MSTEIKTQVVVLGAGPAGYSAAFRCADLGLETVIVERYNTLGGVCLNVGCIPSKALLHVAKVIEEAKALAEHGIVFGEPKTDIDKIRTWKEKVINQLTGGLAGMAKGRKVKVVNGLGKFTGANTLEVEGENGKTVINFDNAIIAAGSRPIQLPFIPHEDPRIWDSTDALELKEVPERLLVMGGGIIGLEMGTVYHALGSQIDVVEMFDQVIPAADKDIVKVFTKRISKKFNLMLETKVTAVEAKEDGIYVTMEGKKAPAEPQRYDAVLVAIGRVPNGKNLDAGKAGVEVDDRGFIRVDKQLRTNVPHIFAIGDIVGQPMLAHKGVHEGHVAAEVIAGKKHYFDPKVIPSIAYTEPEVAWVGLTEKEAKEKGISYETATFPWAASGRAIASDCADGMTKLIFDKESHRVIGGAIVGTNGGELLGEIGLAIEMGCDAEDIALTIHAHPTLHESVGLAAEVFEGSITDLPNPKAKKK
What is the function of this protein?
Lipoamide dehydrogenase is a component of the glycine cleavage system as well as of the alpha-ketoacid dehydrogenase complexes.
What are the official names of this protein?
Dihydrolipoyl dehydrogenase, Dihydrolipoamide dehydrogenase, E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes, Glycine cleavage system L protein.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_IGNH4
Sequence: MTVVVISGPPGSGKSTVAKKLASELGLRFVSAGSVFRKLAEEIGVSLLELNEMALKDPEIDLRIDRMVLEEARRGNVVIEAHLGGWVAAPYADVNVYLTAPLEERAKRIARRDGISYEEALEEILSREEVQWIRFRKLYGFDVASLEIFDLVVNTALMGPEAVVETIKRMLL
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RN2X1_LITCT
Sequence: SMLSVLKNLGKVGLGFVACKINKQC
What is the function of this protein?
Antibacterial activity against Gram-positive bacterium S. aureus (MIC=50 uM) and Gram-negative bacterium E. coli (MIC=2 uM).  Has activity against C. albicans (MIC=70 uM).  Shows no detectable hemolytic activity towards human erythrocytes.
What are the official names of this protein?
Ranatuerin-1.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Ranatuerin subfamily.
Protein: RUVA_CERSK
Sequence: MIGKVAGILDFRGPDHVLIDVRGVGYIVYVSDRTLASMPGLGEAVALYTELVVREDLLQLFGFPTMIEKEWHRLLMTVQGVGAKAGMAILGALGAEGTARAITLGDARSIQAAPGIGPKIAQRVVLELKSKAPALMAMGGGTAALAPSEPPEPQPGTSSGSRRKTRAPEPPRPSHTADALSALANLGYQPTDAAQAVAQAAGESPDADTAALIRAALKLLAPKS
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: CLAT_CHICK
Sequence: MPDLEKDMQKKEKDSRSKDEPAVPKLPVPPLQQTLQMYLQCMKHLVPEEQFRKTKSIVEQFGVAGGLGESLQLILEERREETTNWVFNYWLDDMYLNNRLALPVNSSPAIIFARQNFKDVNDQLRFAANLISGVQDYKALLDSHALPVDFARGQLSGQPLCMKQYYGLFSSYRLPGHTKDTLVAQKSCVMPEPEHIIVACNNQLFVLDVGINFRRLSEGDLFTQLRKIAKMAENEEEMLPPIGLLTTDGRTEWAEARTILMKDSTNRDSLDMIERCICLVCLDGTSGVELNDTNMALQLLHGGGYHKNGANRWYDKPMQFVVGRDGVCGTVCEHSPFDGIVLVQCTEHLLKHMKESSKKLLRADSVSELPAPRRLRWKCSPEIQAHLASSAEKLQRIVKNLDFIAYKFVNYGKEFIKKQKTSPDAYIQVALQLAFYRCHRRLVPTYESASIRRFDEGRVDNIRSATAEAFAFVKAMIDDKPALSDSEKMQRFKDAIAAQTNYTILAITGMAIDNHLLGLREVAREHFKELPEIFTDETYLTSNRFILSTSQVPTPMEMFCCYGPVVPNGYGACYNPQPEHILFCISSFKDCKETSSDMLAKAVEESLLEIRDLCNKCSSSTAKSLAKQEEATQLRSDRKL
What is the function of this protein?
Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses.
What are the official names of this protein?
Choline O-acetyltransferase, CHOACTase, ChAT, Choline acetylase.
What is the protein family that this protein belongs to?
Belongs to the carnitine/choline acetyltransferase family.
Protein: PPIB_YARLI
Sequence: MKLFATIGVLLVALLAFFVQPAQAEPDAEITHKVYFDIKQGEESLGKIVMGLYGDVVPKTVENFRALCTGETGKGYKGSKFHRVIKNFMIQGGDFTRGDGTGGESIYGRKFPDENFQLKHTKPYKLSMANAGRDTNGSQFFITTVVTSWLDGKHVVFGEVLEGQDIVDAIENAPTGARSNPKVDITIADAGEIPVEKSETKEAEPAKEDAKEPKEDVKKKGKSDKDEL
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase B, PPIase B, Rotamase B.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase B subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: NIFK_SINFN
Sequence: MPQSAEKILDHAPLFREPEYRQMLAEKKLNFECPHPERLVTDQREYSKGWEYREKNLAREALVVNPAKACQPLGAVFAAAGFERTMSFVHGSQGCVAYYRSHLSRHFKEPASAVSSSMTEDAAVFGGLKNMVDGLANTYALYDPKMIAVSTTCMAEVIGDDLHGFIENAKSEGAVPPEFDVPFAHTPAFVGSHVDGYDSMVKGILEHFWKGQARTQAAGTINIIPGFDGFCVGNNRELQRLLTLMGVSYTFIQDASDQFDTPSDGEYRMYDGGTTIKALRAALNAEATLSLQHYNSRKTLEYCREVGQATAAFHYPLGINATDAFLMKVSAISGREIPETIRLERGRLVDAMADSQSWLHGKTYAIYGDPDFVYAMARFVMETGGEPRHCLATNGTAAWQAEMTELLASSPFGKQAKVWPGKDLWALRSLLFTEPVDLLIGNSYGKYLERDTGTPLIRLMFPIFDRHHHHRFPLMGYQGGLRLLTTILDTIFDRLDRETMQTAVTDYSYDLTR
What is the function of this protein?
This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.
What are the official names of this protein?
Nitrogenase molybdenum-iron protein beta chain, Dinitrogenase, Nitrogenase component I.
What is the protein family that this protein belongs to?
Belongs to the NifD/NifK/NifE/NifN family.
Protein: RCEL_RHOPA
Sequence: MAMLSFEKKYRVRGGTLIGGDLFDFWVGPFYVGIFGVMTVFFALIGIALIAWNTALGPTWNLWQISVNPPDAKYGLGFAPLAEGGIWQWVSICATGAFVTWALREVEICRKLGIGFHVPFAFSFAIFAYVTLVVIRPVLMGSWSYGFPYGIFTHLDWVSNTGYSYGQFHYNPAHMIAITFFFTTCLALALHGGLVLSALNPDRGEPVKSPEHENTVFRDLVGYSIGTIGIHRLGLFLALSAVFFSAVCMIISGPVLAEGGSWPDWWNWWRNLPIWNP
What is the function of this protein?
The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis.
What are the official names of this protein?
Reaction center protein L chain, Photosynthetic reaction center L subunit.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Cellular chromatophore membrane; Multi-pass membrane protein.
Protein: YIDC_STAA1
Sequence: MKKKALLPLFLGIMVFLAGCDYSKPEKRSGFFYNTFVDPMKNVLDWLGNNLLNDNYGLAIIILVLVIRIILLPFMLSNYKNSHMMRQKMKVAKPEVEKIQEKVKRARTQEEKMAANQELMQVYKKYDMNPIKSMLGCLPMLIQLPIIMGLYFVLKDQLVDGLFKYPHFLWFDLGRPDIWITIIAGVLYFIQAYVSSKTMPDEQRQMGYMMMVISPIMIIWISLSSASALGLYWSVSAAFLVVQTHFANIYYEKVAKKEVQPFIEAYEREHNGGSNKKGKNTQVVSKKKKK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GATC_STAAM
Sequence: MTKVTREEVEHIANLARLQISPEETEEMANTLESILDFAKQNDSADTEGVEPTYHVLDLQNVLREDKAIKGIPQELALKNAKETEDGQFKVPTIMNEEDA
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: Y1016_ARCFU
Sequence: MGGIMDARRLEDEVEMPLEGIVYGEVSGWLTIIGILVAIAGIIIGVVTGNSVFDYQSTIKDLLSGHDEEKIWTDDSIFHSEPHGYWFLNVIHTGDGIAMFGIALAVYGGIVGLLLLIVFTFRSREVLLYKKGLYTFLAIAIFCLMVYCAWEAEF
What are the official names of this protein?
Uncharacterized protein AF_1016.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.