PharMolix/UniProtQA huggingface dataset:
Protein: ATPD_BACFN
Sequence: MEVGIISMRYAKALMAYAEERGAEERLYHELVTLAHSFRTVKGFCAVLDNPIVSVNEKFNLICTAADGDHKPSEEFIRFIRLVLKERRETYLQFMSLMYLDLYRKKKHIGVGKLITAVPVDKATEERIRQTAAHILHAYMELETVVDPSIEGGFVFDINDYRLDASIATQLKKVKQQFIDKNRRIV
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LEUD_ALIFM
Sequence: MSGFKQHTGLVVPLDTANIDTDAIIPKQFLQKVNRIGFGKHLFHDWRFLDDAGEQPNPEFVMNAPRYQGATVLLARENFGCGSSREHAPWALADYGIQVMIAPSFADIFYGNSINNQMVPVRLTESEVDEIFQFVEANEGAEVTVDLEVMLVTANNKQYSFEIDEFRRHCLLNGLDNIGLTLQHADKISEYEAKIPSFLK
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: DCE1_PIG
Sequence: MASSTPSSSATSSNAGPDPNTTNLRPTTYDTWCGVAHGCTRKLGLKICGFLQRTNSLEEKSRLVSAFKERQSSKNLLSCENSDRDGRFRRTETDFSNLFARDLLPAKNGEEQTVQFLLEVVDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGVRTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEIAPVFVLMEQITLKKMREIVGWSNKDGDGIFSPGGAISNMYSIMAARYKYFPEVKTKGMAAVPKLVLFTSEHSHYSIKKAGAALGFGTDNVILIKCNERGKIIPADLEAKILEAKQKGYIPLYVNATAGTTVYGAFDPIQEIADICEKYNLWLHVDAAWGGGLLMSRKHRHKLSGIERADSVTWNPHKMMGVLLQCSAILVKEKGILQGCNQMCAGYLFQPDKQYDVSYDTGDKAIQCGRHVDIFKFWLMWKAKGTVGFENQINKCLELAEYLYAKIKNREEFEMVFDGEPEHTNVCFWYIPQSLRGVPDSPERREKLHRVAPKIKALMMESGTTMVGYQPQGDKANFFRMVISNPAATQSDIDFLIEEIERLGQDL
What is the function of this protein?
Catalyzes the synthesis of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) with pyridoxal 5'-phosphate as cofactor.
What are the official names of this protein?
Glutamate decarboxylase 1, 67 kDa glutamic acid decarboxylase, GAD-67, Glutamate decarboxylase 67 kDa isoform.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
Protein: BIOC_SERMA
Sequence: MTSANDTVNKQAVASAFSRAAGSYDAAAALQRDVGERLLGMGSSHPGEQLLDAGCGTGYFSRMWRERGKRVTALDLAPGMLDVARQRQAAHHYLLGDIEQVPLPDAAMDICFSSLVVQWCSDLPAALAELYRVTRPGGVILFSTLAAGSLQELGDAWQQVDGERHVNAFLPLTQIRTACAAYRHELVTELRTLNYPDVMTLMRSLKGIGATHLHQGREGGLMSRGRLAALQAAYPCRQGQFPLSYHLAYGVIYRE
What is the function of this protein?
Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM).  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.
What are the official names of this protein?
Malonyl-[acyl-carrier protein] O-methyltransferase, Malonyl-ACP O-methyltransferase, Biotin synthesis protein BioC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: OTC_NITHX
Sequence: MSTAPRHFLDLFDVPTTELRAILDASVAMKKRRKEGRIADKPLDGKTLAMIFDKPSTRTRVSFDVGMRQLGGEAIMLTGAEMQLGRGETIADTARVLSRFVDIIMIRILSHDALTELAAHATVPVINGLTRRSHPCQVMADVMTFEEHRGPIKGRTVAWTGDDNNVLASWAHAADRFSFNLNVATPPELAPNKLLKDWIRSSGASIKLGTNPEAAARGADCIVTDTWVSMGDKDGEHRHNLLKPYQVNAKLMSLAKPDALFMHCLPAHRGDEVTDEVIDGPQSVVFDEAENRMHAQKGILAWCLGAAG
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGAM5_DROWI
Sequence: MRKFTAFACGTGAGLAAFYLQRLRDPKQTAWVHNSWTNSERPVDSWALWDSNWDCRDPKSLVRPQKNEQPQEQNRYNSDFEKNHAKSARHIILIRHGEYLDVGDTDDTHHLTERGREQAKFTGQRLHDLGIKWDKVIASTMVRAQETADIILNEIDYDKAKVTNCAYLREGAPIPPQPPVGHWKPEASQFFRDGARIEAAFRRYFHRAYPDQTKESYTLIVGHGNVIRYFVCRALQFPPEAWLRISINHASITWLTISPSGNVSIKYLGDSGFMPVKHLTNRIPRDAKNVV
What is the function of this protein?
Displays phosphatase activity for serine/threonine residues, and dephosphorylates and activates Pk92B kinase.  Has apparently no phosphoglycerate mutase activity (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase Pgam5, mitochondrial, Phosphoglycerate mutase family member 5 homolog.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: HISX_LEPBP
Sequence: MPIPILHCDRNSKELYSRFLQGAREDLTTATDRILPILESVRTQGDQALFSYTEMFDGIKLSQLTIDPKKIKTNVDEKTKEAFLRAKSNIEAFHMEQKRESWSKVIDGNRLGVKYTPIPSLAVYAPGGKALYPSSVLMGIIPAKIAGVPSIQLITPPQKDGIPEILVWLAQIMDIDRIVTVGGAQGIAAAAYGTESVPKSEFIVGPGNAYVAAAKSYLSGQGLIGIESPAGPSEVCIIADENANPKWIACDMLSQAEHGEDSSAILLTTDLTLAKRVSEELEIAFSERPKRLQMKQTAIYENSSILVFPTLDDCIWFSNELAPEHLEIQTKDYESVFAKIEHAGSVFLGPYSPVAMGDYISGTNHILPTARGSRIYSSLGVDTFLKRVTFQEVTKESLENLYPFVKLMSELEGLDEEHGTSVKVRTRQFQ
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: PRO1_NEUCR
Sequence: MSTQSPNHHEDITKTSSVNMTTTTTTTKTKAAAKAGTNAAPKQKTQMHRRSRTGCYTCRLRRKKCDEGSPMCTACKHLGLCCEYKRPMWWSNNDARRKQKDEIKMIIKRKKLSEKSSHTIQTSINTPPGLSHSLPTSATFSDPLDRNRSASIDSHFGFNFNSPQHGQDFAAFATPQIHVNGEYMFPPFSPYEIDMKTERQIFINDIPTLRESTVSTFSTYQTPPPPGTILPSFPLEGEWTEQVFSERRESLTEETFNANFFDFACDPAMASSQVAIELDDGDQKLLDHFVQHVLPTIFPILESNQHGSISSELVLPSLANNKGYLHCCLSIAAQHFKSTMGIQNEEIDNDIMRHRYATITWLCEALNRDENHQPILDATLGLIFFQCIVGRPEDTLPDIPWHQHFQAVVSLVQKLDLAGLVSDITKPLAHTPFNMTLTSWIDILGATMLGSSPLFAHTYRNKHLSINNHSLGLRELMGCEDRVMYLISEIACLESLKNQGMDDITLCQHVRGLGDEISNTEVNEGTLVEPYNANGTLSPKQLSKNITAAFRLAARIYLCSLVPGFYPAQPSCMGLVEKLTAVLQLIPSGVNGYDRSLTWVYLIGGSVSVPGSSFRDFFENRVAQLGDVANSGSFGRMTVLLREVWLQYEAILAAAEAAAGTSSLSSETPQQQQQVNAHYVRWREVMQIKGWDYLLI
What is the function of this protein?
May be involved in fruiting body development.
What are the official names of this protein?
Transcriptional regulatory protein pro1, Arrested development protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: GPMA_ECOL6
Sequence: MAVTKLVLVRHGESQWNKENRFTGWYDVDLSEKGVSEAKAAGKLLKEEGYSFDFAYTSVLKRAIHTLWNVLDELDQAWLPVEKSWKLNERHYGALQGLNKAETAEKYGDEQVKQWRRGFAVTPPELTKDDERYPGHDPRYAKLSEKELPLTESLALTIDRVIPYWNETILPRMKSGERVIIAAHGNSLRALVKYLDNMSEEEILELNIPTGVPLVYEFDENFKPLKRYYLGNADEIAAKAAAVANQGKAK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: UPPP_PSYA2
Sequence: MDIILLIQAVIMGIVEGITEFLPISSTGYLILSADLMGFWTKEKVDLFVVVVQFGAILAVIYDYWDRLWQALMGLLTGKAEGMSNPRQLGLSLIVATIPVMIVGFTFADEIKAYLFDPIVVAIMLIIGGLLIFYVENRPKPIIAQEAEDVGLKTALMIGLFQCLALIPGTSRSGATIVGALWLGVSRKASAEFSFFLGIPVIVGAALLDLLKHKDVLTSSEDWLVLGIGTVVSFIVALLCIRLLVAWVSRRDFKIFAWLRIITGVLVLIAAWGFGYQMAG
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: APOE_BOSMU
Sequence: MKVLWVAVVVALLAGCQADMEGELGPEEPLTTQQPRGKDSQPWEQALGRFWDYLRWVQTLSDQVQEELLNTQVIQELTALMEETMKEVKAYKEELEGQLGPMAQETQARVSKELQAAQARLGSDMEDLRNRLAQYRSEVQAMLGQSTEELRARMASHLRKLRKRLLRDADDLKKRLAVYQAGASEGAERSLSAVRERFGPLVEQGQSRAATLSTLAGQPLLERAEAWRQKLHGRLEEVGVRAQDRLDKIRQQLEEVHAKVEEQGNQMRLQAEAFQARLRSWFEPLVEDMQRQWAGLVEKVQLALRPSPTSPPSENH
What is the function of this protein?
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids.  APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance.  Apolipoproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma.  As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL).  It also binds a wide range of cellular receptors including the LDL receptor/LDLR and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles.  Finally, APOE has also a heparin-binding activity and binds heparan-sulfate proteoglycans on the surface of cells, a property that supports the capture and the receptor-mediated uptake of APOE-containing lipoproteins by cells.
What are the official names of this protein?
Apolipoprotein E, Apo-E.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix. Note=In the plasma, APOE is associated with chylomicrons, chylomicrons remnants, VLDL, LDL and HDL lipoproteins. Lipid poor oligomeric APOE is associated with the extracellular matrix in a calcium- and heparan-sulfate proteoglycans- dependent manner. Lipidation induces the release from the extracellular matrix.
Protein: ATPA_BIFLD
Sequence: MAELTIDPASIRKALDDFVSSYKPSDTPTQEVGYVATAGDGIAHVTGLPGCMANELLTFEDGTLGLAFNLDAREIGVVILGDFAGIEEGQEVRRTGEVLSVPVGDGYLGRVVDPLGKPLDGLGEIQGIEGRRILEAQAPDVMHRHPVDEPLSTGLKAIDAMTPIGRGQRQLIIGDRQTGKTAIAIDTIINQKANWESGDPKKQVRCIYVAIGQKGSTIASVKQSLEDAGAMEYTTIVASPAADSAGFKYIAPYTGSAIGQHWMYNGKHVLIVFDDLSKQAEAYRSISLLLRRPPGREAYPGDVFYLHSRLLERCAKVSDDLGGGSMTGLPIVETKANDVSAYIPTNVISITDGQIFLQSDLFNANQRPAVDVGISVSRVGGAAQTKALKKVSGTLKISLAQYRSLESFAMFASDLDAASKAQLTRGAHLTELLKQPQFHPYSPEQEVVSVWTGTHGKLDDLDLKDVLPFEQGLLDYIDHNTDILKTIRETEEFTADTEAALDKAVDEFRSTFVSSAGKPLVEKKPDVDKAAPVDQEKIVAGEK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HXC4A_DANRE
Sequence: MIMSSYLMDSNYIDPKFPPCEEYSQNSYIPEHSPEYYSRARDSGYQHHHQELYPPRASYQERQYNCASIPEPDTQRGHGLPHAGHLLGKGQSASCEPPPLPLSPATPSAASSACNQATPEHPNSSASAKQPVVYPWMKKIHVSTVNSSYNGAEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLVLSERQIKIWFQNRRMKWKKDHRLPNTKVRSSSSTGISSGSNTSSAAGVVAAASTTNTMSASEDLSGTERGEDITRL
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-C4a, Hox-C4.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family. Deformed subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RF3_STRU0
Sequence: MSIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVKGKKSGTFAKSDWMDIEKQRGISVTSSVMQFDYAGKRVNILDTPGHEDFSEDTYRTLMAVDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFINKLDRDGREPLELLEELEEVLGIASFPMNWPIGMGKAFEGLYDLHNNRLELYKGENRFADLEEGAKLFANNPFYEQVLDDIELLQEAGNEFSEEAILSGELTPVFFGSALTNFGVQTFLDTFLEFAPEPHGHKTKEGQMIDPLEKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFVKGMGVNLTRTGKGAKLSNVTQFMAESRENVQNAVAGDIIGVYDTGTYQVGDTLTVGKHKFEFEPLPTFTPELFMKVSPKNVMKQKSFHKGMEQLVQEGAVQLYRNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAEVIMTPMGKKTVRWIKEEDLDQRMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDVQLEEKM
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HORM1_PIG
Sequence: MATAQLQRTSMSALVFPNKISTEQQSLVLVKRLLAVSVSCITYLRGIFPECAYGTRYLDDLCVKILREDKNCPGSTQLVKWMLGCYDALQKKYLRMVVLAVYTNPEDPQTISECYQFKFKYTSNGPIMDFISKNQSSESSMSSADTKKASILLIRKIYILMQNLGPLPNDVCLTMKLFYYDEVTPPDYQPPGFKDGDCEGVIFEGEPMYLNVGEVPTPFHTFKVKVTTEKERMENIYSGILSPKQIKTPLQKILMDKDDLEDEQEHYINDDFDIETKMEEQKKKLGSSELGEPNLVCEEDEIMRSKESPELSISHSQVEQLVSKTSELDVSESKTRSGKIFQNKMANGNQQIKSKESRKRSQLESGKTVLHHFDSSSQDSVPKRRKFSEPKEHI
What is the function of this protein?
Plays a key role in meiotic progression.  Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single-stranded DSB ends.  Promotes synaptonemal-complex formation independently of its role in homology search.  Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes.
What are the official names of this protein?
HORMA domain-containing protein 1.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Preferentially localizes to unsynapsed or desynapsed chromosomal regions during the prophase I stage of meiosis. TRIP13 is required for depletion from synapsed chromosomes. The expression of the phosphorylated form at Ser- 377 is restricted to unsynapsed chromosomal regions (By similarity).
Protein: YL183_MIMIV
Sequence: MCDFVFCYGSSNERKLSMNIKETKKGLQLYVSNSEYIYIEIKKTYRKNLVINFEDSLKFMKFLVRKKIHCQFLTDKHGCGFCKNYREYFQYIVQNKHMKHIKFFVGKFIPMIRSRCGYSEFNLSNVVEDNKIFENNNIDLEIVKYMFEIGNLFDVDYIVVHVLTELDDIEIDFIDSLIDIYKQKITYLFTEDFSDIDNLLYTVLDLNIFITPALKTDDINLFNYVVEELSSIMSDIKEEELSKKQIIPFKKIKSKYILDADRIFKLIDICVGSFYEKSFHCPNIFKQLVEDYIENHGSIRLLFNNFFRKIVANDKFAYAGILCEKVNSDQNFLRKILFESVGSIKEAQILIDYGLDHEEIYEDPDFRKLPKTITKFIKKLIKETSN
What are the official names of this protein?
Uncharacterized protein L183.
What is the protein family that this protein belongs to?
Belongs to the mimivirus L17x/L18x family.
Protein: IRC22_YEAS6
Sequence: MRFFMLIGFNLLTALSSFCAAISANNSDNVEHEQEVAEAVAPPSINIEVKYDVVGKESENHDSFLEFYAEDTATLAYNVTNWEDTNITIFGVNGTIVTYPHGYPVADITGASIGPYEMEVNGTSKFGQDVTLNLPEGQYFLIPFLLASRFDEIVRIAAPPTLFEIVSPPISFFNPQFLSVQVIFLAIIGGVSYYYMKSKTNQRPSKKSATVKKVDESWLPETYKK
What is the function of this protein?
Is probably involved in a pathway contributing to genomic integrity.
What are the official names of this protein?
Increased recombination centers protein 22.
What is the protein family that this protein belongs to?
Belongs to the IRC22 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: AROE_PASMU
Sequence: MDKYAVWGNPIAQSKSPQIHQIFANQTQQQMEYVAMLGDEQDFEQQLRVFFEKGAKGCNITAPFKERAFQLADLHSERCLTAEACNTLKKLDDGRLYGDNTDGAGLVSDLQRLGWLKPEQTILILGAGGATKGVLLPLLQAKQHIVLANRTLSKAEDLAQKFAQYGQIQAVELDNIPVQSFDLIINATSSGLHGQTVQMNPEILQNATALYDMQYAKQADTPFVALCKQLGKQNVSDGFGMLVAQAAHAFHLWRGVMPEFEALLEQEWL
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: PGM1_MACFA
Sequence: MVKIVTVKTQAYPDQKPGTSGLRKRVKVFQSSANYAENFIQSIISTVEPAQRQEATLVVGGDGRFYMKEAIQLIARIAAANGIGRLVIGQNGILSTPAVSCIIRKIKAIGGIILTASHNPGGPNGDFGIKFNISNGGPAPEAITDKIFQISKTIEEYAICPDLKVDLGVLGKQQFDLENKFEPFTVEIVDSVEAYATMLRNIFDFSALKELLSGPNRLKIRIDAMHGVVGPYVKKILCEELGAPANSAVNCVPLEDFGGHHPDPNLTYAADLVETMKSGEHDFGAAFDGDGDRNMILGKHGFFVNPSDSVAVIAANIFSIPYFQQTGVRGFARSMPTSGALDRVANATKIALYETPTGWKFFGNLMDASKLSLCGEESFGTGSDHIREKDGLWAVLAWLSILATRKQSVEDILKDHWQKYGRNFFTRYDYEEVEAEGANKMMKDLEALMFDRSFVGKQFSANDKVYTVEKADNFEYSDPVDGSISRNQGLRLIFTDGSRIIFRLSGTGSAGATIRLYIDSYEKDVAKINQDPQVMLAPLISIALKVSQLQERTGRSAPTVIT
What is the function of this protein?
This enzyme participates in both the breakdown and synthesis of glucose.
What are the official names of this protein?
Phosphoglucomutase-1, PGM 1, Glucose phosphomutase 1.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF_MYCSK
Sequence: MAVVPIRIVGDPVLRTETTPIPVGDDGSLPAEVADLIRDLYETMDAANGVGLAANQIGVSQRVFVYDCPDSRGRAGRRRGVVINPVLETSDIPETMPDPDDDEEGCLSVPGEQFPTGRADWARVTGLDADGSPITVEGTGLFARMLQHETGHLDGFLYLDRLIGRHARAAKRAVKHNGWGVPGLSWTPGEDPDPFGH
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: NQRE_YERPP
Sequence: MEHYISLLVRAVFVENMALAFFLGMCTFLAVSKKVSTAFGLGIAVTVVLGISVPANNLVYNLVLRDGALVEGVDLSFLNFITFIGVIAAIVQVLEMILDRYFPALYNALGIFLPLITVNCAIFGGVSFMAQRDYNFPESIVYGFGSGMGWMLAIVALAGIREKMKYANVPAGLQGLGITFISTGLMALGFMSFAGVNL
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit E, Na(+)-NQR subunit E, Na(+)-translocating NQR subunit E, NQR complex subunit E, NQR-1 subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRUA_CALBD
Sequence: MRNILLTIEYDGTGYFGWQKQPNKKTIQGTIEEAIKKLTGEEVNLIGSGRTDRGVHALNQKANFKTSSKIPTDKFPLALNSVLPGDISIKDAVEAPLDFSARYSARQKTYKYLIYNKKSRPALLRNYAYYYPYQLDVDAMQRACEYFIGEYDFKSFCSADSEAKTTIRRVYNAYLTFENECIAIYITANGFLYNMARIIAGTILDVGAGKLKPMDIPLIIESKDRTKAGKTLPPWGLYLVDVVY
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: NUSB_BACC2
Sequence: MKRRTARERAMQALYQMDITGELEPKVAVENTLDEGEETNEFLESLVVGFVENKEAIDEAIRQNLKKWKLERISIVDRSILRVAVYEMKYMEEIPHNVTINEAIEIAKTFGDEESRRFINGVLSNIKDTL
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: GLPK_PHOLL
Sequence: MIEKKYIVALDQGTTSSRAIILDHDANIISISQREFTQIYPKPGWVEHDPMEIWATQSSTLVEVLAKADISSDQIAGIGITNQRETTIIWEKETGKPIYNAIVWQCRRTADACTKLKQKEGLEEYIRQNTGLVVDPYFSGTKVKWILDNVAGARERAEKGELLFGTVDTWLVWKMTQGRVHVTDFTNASRTMLFNIHNLEWDQHILDELQIPRSLLPSVHSSSEIYGQTNIGGKGGTRIPISGIAGDQQAALYGQLCVQPGMAKNTYGTGCFLLMNTGTDAVRSNHGLLTTIACGPRGEVNYALEGAVFVGGASIQWLRDELKLIADAADSEYFATKVKNSNGVYVVPAFTGLGAPYWDPYARGSIFGLTRGTNSNHIIRATLESIAYQTRDVLDAMQADAGTRLQALRVDGGAVANNFLMQFQSDILGTRVERPVVRESTALGAAFLAGLAVGYWKDLDEVKSKATIEKEFRPGIETTERNYKYNGWKKAVARAQDWEDKG
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: HIS2_PSEP1
Sequence: MSDTLNRLAEVLEERKQAAPDSSYVASLYHKGLNKILEKLGEESVETIIAAKDAQISKDYSDVIYETADLWFHSLVMLSALGQHPQAVLDELERRFGLSGHDEKAARQPSA
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_SALEP
Sequence: MSNRKYFGTDGIRGRVGNAPITPDFVLKLGWAAGKVLARHGSRKIIIGKDTRISGYMLESALEAGLAAAGLSASFTGPMPTPAVAYLTRTFRAEAGIVISASHNPFYDNGIKFFSIDGTKLPDDVEEAIEAEMEKEITCVDSAELGKASRIVDAAGRYIEFCKGTFPNELSLNGLKVVVDCANGATYHIAPNVLRELGATVIAIGCEPNGVNINEEVGATDVRALQARVLAEKADLGIALDGDGDRVIMVDHEGNKVDGDQIMYIIAREGLRQGQLRGGAVGTLMSNMGLELALKQLGIPFARAKVGDRYVLEKLQEKGWRIGAENSGHVILLDKTTTGDGIVAGLQVLAAMVRNHMSLHDLCSGMKMFPQILVNVRYTAGSGDPLENEAVKAVTADVEATLGNRGRVLLRKSGTEPLIRVMVEGEDEAQVTAFAHRIADAVKAV
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: Y1956_ALKOO
Sequence: MNNSRFLVIDKEILPDIFEKVIEAKELLRTNQVKGVTEATKAVGISRSAFYKYKDYVYTLSDSNVGKKVTLSFLLSHQAGVLSNVLHIISVNNGNILTINQDSPINNFANVNIIFDITEISKKLDDIIQEIESIDGVEKLEILALE
What are the official names of this protein?
UPF0735 ACT domain-containing protein Clos_1956.
What is the protein family that this protein belongs to?
Belongs to the UPF0735 family.
Protein: YBF5_YEAST
Sequence: MWGILLKSSNKSCSRLWKPILTQYYSMTSTATDSPLKYYDIGLNLTDPMFHGIYNGKQYHPADYVKLLERAAQRHVKNALVTGSSIAESQSAIELVSSVKDLSPLKLYHTIGVHPCCVNEFADASQGDKASASIDNPSMDEAYNESLYAKVISNPSFAQGKLKELYDLMNQQAKPHDTSFRSIGEIGLDYDRFHYSSKEMQKVFFEEQLKISCLNDKLSSYPLFLHMRSACDDFVQILERFIAGFTDERDTFQLQKLGASSSSGFYKFHPDRKLVVHSFTGSAIDLQKLLNLSPNIFIGVNGCSLRTEENLAVVKQIPTERLLLETDAPWCEIKRTHASFQYLAKYQEVRDFEYPAFKSVKKNKLADKLNAEELYMVKGRNEPCNMEQVAIVVSEVKDVDLATLIDTTWKTTCKIFGE
What is the function of this protein?
Has both endo- and exonuclease activities.  Incises double-stranded DNA without obvious specificity via its endonuclease activity and excises the DNA from the 3'-to 5'-end by its exonuclease activity.  May have a role in apoptosis.
What are the official names of this protein?
Deoxyribonuclease Tat-D.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.
What are the subcellular locations of this protein?
Cytoplasm.