PharMolix/UniProtQA huggingface dataset:
Protein: EFP_NEIME
Sequence: MKTAQELRAGNVFMVGNDPMVVQKTEYIKGGRSSAKVSMKLKNLLTGAASETIYKADDKFDVVILSRKNCTYSYFADPMYVFMDEEFNQYEIEADNIGDALKFIVDGMEDQCEVTFYEGNPISVELPTIIVREVEYTEPAVKGDTSGKVMKTARLVGGTEIQVMSYIENGDKIEIDTRTGEFRKRA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SASA_PROM2
Sequence: MNDKKELKLILVAARNQLSSGDIKSLIAYLESNDCEFEISLQISEPTEQPELLELHRLVAIPALIKISPAPKQIFAGSNIFSQFQKWLPRWTQEGLTKNLGINLQPSKIDSIRTQKEFLLEDELLVLRQENETLTKRIESQERLLRMVAHELRTPLTAATLAIQSQKLGQIDISKLQEVIKRRLEEIELLSQDLLEVGTTKWEALFNPQKIDLGNISAEVILELEKFWRLRNIEIDTDIPSDLPSVFADQRRMRQVLLNLIENAIKFSEDSGSIKITMIHKTNQWVEITICDKGAGIPLSEQKRIFLDRVRLPQTSEGTSGFGIGLSVCRRIVQVHGGRIWVVSELSEGSCFHFTVPVWQGQNKEQQYLTKG
What is the function of this protein?
Member of the two-component regulatory system SasA/RpaA involved in genome-wide circadian gene expression.  One of several clock output pathways.  Participates in the Kai clock protein complex, the main circadian regulator in cyanobacteria, via its interaction with KaiC.  KaiC enhances the autophosphorylation activity of SasA, which then transfers its phosphate group to RpaA to activate it.  In addition to its output function, recruits fold-shifted KaiB (KaiB(fs)) to KaiC to cooperatively form the KaiB(6):KaiC(6) complex (independent of SasA kinase activity).  Required for robustness of the circadian rhythm of gene expression and is involved in clock output, also required for adaptation to light/dark cycles.
What are the official names of this protein?
Adaptive-response sensory kinase SasA, Sensor histidine kinase SasA.
Protein: FABR_ECOHS
Sequence: MGVRAQQKEKTRRSLVEAAFSQLSAERSFASLSLREVAREAGIAPTSFYRHFRDVDELGLTMVDESGLMLRQLMRQARQRIAKGGSVIRTSVSTFMEFIGNNPNAFRLLLRERSGTSAAFRAAVAREIQHFIAELADYLELENHMPRAFTEAQAEAMVTIVFSAGAEALDIGVEQRRQLEERLVLQLRMISKGAYYWYRREQEKTAIIPGNVKDE
What is the function of this protein?
Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis.  By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer.
What are the official names of this protein?
HTH-type transcriptional repressor FabR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIE_CHLPD
Sequence: MIPAKPFLCVITDEQCSSPVDLALMALEGGAEMIQLRHKSASGKQLFQWALDIQRLCRIHHAQFIVNDRVDIALAMNADGVHLGQQDLQPGEARKLLGTDKIIGVSTSSLTEALNAERAGADYIGFGHIFQTGSKNKLSAPLGSAAISAVVQRISIPLVAIGGINKMNMMETIAAGASGIAMIAAISRTADPEGATRAITELLKGH
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: G3P_ASHGO
Sequence: MVKVAINGFGRIGRLVMRIALSRANVEVVAINDPFITVDYAAYMFKYDSTHGKYAGDVQYEGNTLVIDGKKIKVFQERDPAQLPWGEEGIDIAIDSTGVFKELDSAQKHIDAGAKKVVITAPSSTAPMFVMGVNEEKYAGETIVSNASCTTNCLAPLAKVIDEQFGIEEGLMTTVHSLTATQKTVDGPSMKDWRGGRTASGNIIPSSTGAAKAVGKVLPQLNGKLTGMAFRVPTVDVSVVDLTVKLNKETTYDEIKAAIKAASEGKLKGILGYTEDAVVSTDFLGDNNSSIFDASAGIMLSPKFVKLVSWYDNEYGYSTRVVDLVEHVAAN
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK16_CALFG
Sequence: MLSPKRTRFRKQHRGRMKGISYRGNHICFGRYALQALEPSWITSRQIEAGRRAMTRYARRGGKIWVRIFPDKPVTVRPTETRMGSGKGSPEYWVSVVKPGRILYEMGGVSETVARAAISIAACKMPIRTQFIIAR
What are the official names of this protein?
50S ribosomal protein L16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PRIA_RICPR
Sequence: MRIAKILLPVSKLFPLDYLITEDLELNIGDLVVVHFRNKELTGIVWELDTNSEAKKIKTIEAKAPLNLSITLEVLELIKWMSSYYMSELGSIAKLVLPINISEKPIKIKEQQVKNHFVLPKLSEEQKQAVTILNESNKPTLIKGVTGSGKTEIYFHIIADYLIKGRQVLIMLPEIALGKQIINRFIDRFGFEPIIWNSSVTKAQKKMILRGILSNKVKVVIGTRSSLFLPFHNLGLIVIDEEHDDSYKQDDNILYNARDTAIVRGKFDKAKIVLCSATPSLETIYNIKTHKYQLVTLANRYKNVDLPNIEIIDMTKEKLPKNSYLSKILIDAIKGNLENKKQALLFLNRRGYAPLMLCKACGHRFTCKFCSAWMVLHKATKKLECHHCGYQSKIFSSCPECLEDETLTICGPGIERIAEEAMLLFPKSKIAVISKDHAKTPEKIAQLLHQMENLEIDILIGTQIITKGYHFPNLTLVGVIDADLGSNNAELRASERTFQLLHQVGGRAGRGDSKGVVYLQSYYPDNIIFSYVKVGDEDRFFTNELEIRKAANMPPFSKTASLILSGFSESKILDIARKIVQIAPKANVKILGPARSLMSKLAGKYRYRILIIADKKFNLQKYLKFWLGFIKIPSYCQIKIDIDPKTFY
What is the function of this protein?
Involved in the restart of stalled replication forks.  Recognizes and binds the arrested nascent DNA chain at stalled replication forks.  It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
What are the official names of this protein?
Primosomal protein N', ATP-dependent helicase PriA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. PriA subfamily.
Protein: YL779_MIMIV
Sequence: MKKFFIIDAEYLFVYGLYVAENPIKAVTIAYNNTLKDSYHDNIDGETITLLAYEITSVPTIHVINCARYSVNNYMIINGLPTLVEYRLDMKFDDTPIFDLLYF
What are the official names of this protein?
Uncharacterized protein L779.
Protein: RLMH_CLOAB
Sequence: MNITLITVGKLKEKYLKDAVNEYAKRLQKYCKLNIIELQDEKTPEKASLKEEKLIKEKEGEKILSSIKDNSYVVSMDLKGKMFSSEEFSAFIDDLGVRGNSSIDFVIGGSLGLSDAVLARANYKLCFSKMTFPHQLFRVMLLEQVYRAFRISRGEPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GP19_BPLC2
Sequence: MINLQNKKLDIKEFLQELGFTVSLDYEREPMGVMFAEIHPIVSQVSNNSAIYQSFRTLEIELMVICTEETENSLYRAVQLLSDEHYIYANTITDNTNIIKLRGNYYD
What is the function of this protein?
Seems to be involved in escape from killing mediated by the bacterial type III toxin-antitoxin module AbiQ toxin protein upon infection of L. lactis subsp.  lactis strain IL1403.  A single variant independently isolated from 5 different phage confers on the virus the ability to partially escape killing (i. e.  the virus grows in the bacteria).
What are the official names of this protein?
Gene product 19, gp19, AbiQ resistance protein, E19.
Protein: ATPD_BACSU
Sequence: MSGSAVSKRYASALFDIANESAQLNQVEEELIVVKQVFQNEKALNDVLNHPKVPAAKKKELIQNAFGSLSQSVLNTIFLLIDRHRAAIVPELTDEFIKLANVARQTEDAIVYSVKPLTDAEMLPLSQVFAKKAGVASLRIRNEVQTDLIGGIKVRIGNRIYDGSVSGKLQRIERQLAGENR
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Membrane raft; Peripheral membrane protein. Note=Present in detergent-resistant membrane (DRM) fractions that may be equivalent to eukaryotic membrane rafts; these rafts include proteins involved in signaling, molecule trafficking and protein secretion.
Protein: KAD_CHRSD
Sequence: MRLILLGAPGAGKGTQAQFICERFDIPQISTGDMLRAAVKEGSELGLKVKEIMNSGGLVSDDIIIALVKERIAQPDCANGFLFDGFPRTIPQADAMKEANVKLDHVLEVAVDDEEIVTRLAGRRVHPGSGRVYHVDYNPPKEEGKDDVTGEALIQRDDDREATVRNRLSVYHEQTEPLVQYYREWAQQDPQTAPAYHRVEGTGSVEAIRQQVLTALEG
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN488_MOUSE
Sequence: MAAGTSTLLSLSGPADHMAEGKGAPLRPSVEKRWKLMEPKQTQAGMFKKMSLVDSDTAAGKGSQDEAYTELSLPTAPNKPRLDRPRACKAYTEQRHNTFTELSCLQERPGDIQAQTRKLENPEGQLGPQQLPSSFLRASGDGTVCSAWPGAPRSEQKSAFSKPAKRPAEKPKRSPMLLAGGSAEGSWELSGLITTVDIPYWAHLSTFKFMGDFWKLHTLSQNILLCNAFQGAPTPWLEHTQVQAPTSSAPSSTASRALLPPTLSSLGLSTQNWCAKCNLAFRLTADLVFHMRSHHKREHVGPDPHSKKRREEVLTCPVCHEYFRERHHLSRHMASHS
What is the function of this protein?
Transcriptional repressor (PubMed:16908628).  Plays a role in oligodendrocyte differentiation, together with OLIG2 (PubMed:16908628, PubMed:22355521).  Mediates Notch signaling-activated formation of oligodendrocyte precursors (PubMed:16908628).  Promotes differentiation of adult neural stem progenitor cells (NSPCs) into mature oligodendrocytes and contributes to remyelination following nerve injury (PubMed:22355521).
What are the official names of this protein?
Zinc finger protein 488.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PETD_SYNE7
Sequence: MSILKKPDLSDPILRQKLAKGMGHNYYGEPAWPNDLLYMFPVVILGTIACLTGLAVLDPALVGEPADPFATPLEILPEWYLYPVFQILRIVPNKLLGIVLQSMIPLGLIAIPFIESVNKFQNPFRRPIATAVFLFGTVFTLYLGIGAALPIDKSLTLGLF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 4, 17 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetD subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: RPO11_HALMA
Sequence: MDLRVIDKSDTELSIEIAGEDHTFMNVIKGALLETEGVTAATYDVNPEQSGGQTDPVLTIKTEEGVDALEALEDGTDAVIEKADNFTDAFEAAA
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo11, DNA-directed RNA polymerase subunit L.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACUK_PHANO
Sequence: MASPDAEDASPSPEYRSDLDDDMAAEQKTDDGSPSQKSSNGQKPASNAKDPLRPRRKKARRACFACQRAHLTCGDERPCTRCIKRGLQDHCMDGVRKKAKYLHDAPDGALMPGVGGHYPYMNGNRPTPLPSQDTHNVPMAPQGNMYTQAPSGTFYQPPSAQIPLPQAQHGRSFSDQQSPLSPPFSQAHHGPNVNPPSSISQGQPGQMQQFGPLFDPSDPALFNFDISSLNFGNHYGALEFGMLGHMSSAVDAPNDNTMMNAMNQTANMYGPQMAGAYGPNNPNAAMPFAQNSLPAGEWQESQSRQNSMHIHTPTSSATALDHGGHRHDSLNGPHAFAIGQGPSSHSTASPASTDASAFENDNPLSTATFFANTNRGQPQRSPTTNRHHQGNRPPSTALQPIHSNGVRKRHRDTKSIYQGIKKPFDYVKGYHRLFQICHKKFSKSLLAQAQQYLNLYRPVLLSVREEMDTDDLIHQEMGLQRNLMTLQDHFTEVGTPFLICRRSGEIVSCNKEFTILTGWRQDVLLGREPNLNVNLGNSREADESEMSTQTNTTPNLTGQEAETGTPAVNAIQLMDAKSALEYLQNFSELCWQDPHGHAKQRANMLRYQTKADFDRIQEMKANADHKSDAFVKMEGGAVHQGESAMQRLGAKNGMVDCMIWWHIKRDIFEMPVLVCMSVMPVLDKGLQ
What is the function of this protein?
Transcription factor which regulates nonfermentable carbon utilization.  Activator of gluconeogenetic genes (By similarity).
What are the official names of this protein?
Transcription activator of gluconeogenesis SNOG_12336.
What is the protein family that this protein belongs to?
Belongs to the ERT1/acuK family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNPA_PROMI
Sequence: MVKLAFPRELRLLTPKHFNFVFQQPQRASSPEVTILGRQNELGHPRIGLTIAKKNVKRAHERNRIKRLAREYFRLHQHQLPAMDFVVLVRKGVAELDNHQLTEVLGKLWRRHCRLAQKS
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: MRAY_BIFA0
Sequence: MIALIIGILTSLIITLVGTPLLIRIVHKLNYGQYIRQDGPKSHQVKRGTPTLGGVVIVLAVVLGWCASALYRFCTTGARPTWAAILALFAMVSMGVLGFIDDFAKVRKKQNEGLTVGGKFFGQVVFATIFAVLALIVPTRSGFPVAQAGMSFIEKPFLSFEFAGRIVAIILFVIWVNFLMAAWTNAVNLSDGLDGLCAGSSMIAFVGYAIIAMWQMYHLKGQAHSGFTYAVSDPLDLGIIACCAAVACLGFLWYNCNPASIFMGDTGSLALGGLFAALSIITHTEFLAMIIGGLFVVETLSDVIQVGYFKATHKRVFKMAPIHHHFELCGWSESKVVVRFWIVELMFVITGLIIFYGNWVGLSGLWHH
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRMN6_CITK8
Sequence: MSQSTSTLRRNGFTFKQFFVAHDRCAMKVGTDGILLGAWAPVAGVTRILDIGTGSGLLALMLAQRTDESVTIDAVELDSEAATQAQENIAHSPWPQRITVHTEDVRQWVPRQTARFDLIISNPPYYEQGVECATPQREQARYTTTLDHEALLTTAAECITEEGFFCVVLPEQTGNTFTQQALSMGWHLRLRTDVAETESRLPHRVLLAFSPRTGECFSDRLVIRGPDQLYSEGYTALTQAFYLFM
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VE2_HPV18
Sequence: MQTPKETLSERLSCVQDKIIDHYENDSKDIDSQIQYWQLIRWENAIFFAAREHGIQTLNHQVVPAYNISKSKAHKAIELQMALQGLAQSAYKTEDWTLQDTCEELWNTEPTHCFKKGGQTVQVYFDGNKDNCMTYVAWDSVYYMTDAGTWDKTATCVSHRGLYYVKEGYNTFYIEFKSECEKYGNTGTWEVHFGNNVIDCNDSMCSTSDDTVSATQLVKQLQHTPSPYSSTVSVGTAKTYGQTSAATRPGHCGLAEKQHCGPVNPLLGAATPTGNNKRRKLCSGNTTPIIHLKGDRNSLKCLRYRLRKHSDHYRDISSTWHWTGAGNEKTGILTVTYHSETQRTKFLNTVAIPDSVQILVGYMTM
What is the function of this protein?
Plays a role in the initiation of viral DNA replication.  A dimer of E2 interacts with a dimer of E1 in order to improve specificity of E1 DNA binding activity.  Once the complex recognizes and binds DNA at specific sites, the E2 dimer is removed from DNA.  E2 also regulates viral transcription through binding to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory regions of the viral genome.  Activates or represses transcription depending on E2RE's position with regards to proximal promoter elements including the TATA-box.  Repression occurs by sterically hindering the assembly of the transcription initiation complex.
What are the official names of this protein?
Regulatory protein E2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E2 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: SSRP_SHEPC
Sequence: MVKKKSSKAAPATIARNKRATFEYRFEEKMEAGLSLMGWEVKSIRMGKVNLSDCYVFLKNGEAFMHGCTIIPLNTASTHVVCDPLRLKKLLLSRKELDKLAGLVERQGYSIIPISMYWRKGAWVKVEIGLGKGKKDHDKREDTKAREWEVEKARVMKKEKTHG
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: AROE_BACC4
Sequence: MKQLYGVIGNPIGHSLSPVMHNDAFEHLNMDAHYHAFLVEEELLGEAVRGLKALGISGFNVTTPHKVAIMEYLDEIDPLARKIGAVNTVVHKDGRLIGYNTDGIGFVRALQSISNEPLQGKRILLLGSGGASRAIYFSLADVGVKEIDVANRTVDKAKELIAARTADVNSVALSLEKATEEQGNYDIIIQTTTIGMHPHVEHTPLQICSLKKGTIVSDIIYNPFETKILCEAKEQGAIIQNGIDMFVYQGALAFEMWTGRTPNIERMKQLVIEKLGG
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: SBNO1_MOUSE
Sequence: MVEPGQDLLLAALSESGISPNDLFDVDGGDAGLATPTPPSVQQSVPLSALELGLETEAAVPVKQEPEPMSTPALLNVRQPPSTTTFVLNQINQLPTLGSTIVMTKTPPATTNRQTITLTKFIQTTANTRPSVSAPAVRNAMPAAPSKDQVQLKDLLKNNSLNELMKLKPPANIAQPVATAATDVSNGAVKKESSNKEVARIWINDMKMRSFSPTMKVPVVKEEDEPEEEDEEEMGHAETYAEYMPIKLKIGLRHPDAVVETSSLSSVTPPDVWYKTSISEETIDNGWLSALQLEAVTYAAQQHETFLPNGDRAGFLIGDGAGVGKGRTIAGIIYENYLLSRKRALWFSVSNDLKYDAERDLRDIGAKNILVHSLNKFKYGKISSKHNGSVKKGVIFATYSSLIGESQSGGKYKTRLKQLLHWCGDDFDGVIVFDECHKAKNLCPVGSSKPTKTGLAVLELQNKLPKARVVYASATGASEPRNMAYMNRLGIWGEGTPFREFSDFIQAVERRGVGAMEIVAMDMKLRGMYIARQLSFTGVTFKIEEVLLSQSYVKMYNKAVKLWVIARERFQQAADLIDAEQRMKKSMWGQFWSAHQRFFKYLCIASKVKRVVQLAREEIKNGKCVVIGLQSTGEARTLEALEEGGGELNDFVSTAKGVLQSLIEKHFPAPDRKKLYSLLGIDLTAPSNNSSPRDSPCKENKIKKRKGEEITREAKKARKVGGLTGSSSDDSGSESVSDNDESDYESSKNMSSGDDDDFNPFRDESSEDNEDDPWLIRKDHKKSKDKKKKKSIDPDSIQSALLASGLGSKRPSFSSAPVISPASNSAPANSNSNSNSSLVTSQDAVERAQQMKKDLLDKLEKLAEDLPPNTLDELIDELGGPENVAEMTGRKGRVVSNDDGSISYESRSELDVPVEILNITEKQRFMDGDKNIAIISEAASSGISLQADRRAKNQRRRVHMTLELPWSADRAIQQFGRTHRSNQVTAPEYVFLISELAGEQRFASIVAKRLEGLGALTHGDRRATESRDLSRFNFDNKYGRNALEIVMKSIVNLDSPMVSPPPDYPGEFFKDVRQGLIGVGLINVEDRSGILTLDKDYNNIGKFLNRILGMEVHQQNALFQYFADTLTAVVQNAKKSGRYDMGILDLGSGDEKVRKSDVKKFLTPGYSTSGHVELYTISVERGMSWEEATKIWAELTGPDDGFYLSLQIRNNKKTAILVKEVNPKKKLFLIYRPNTGKQLKLEIYADLKKKYKKVVSDDALVHWLDQYNSSADTCTHAYWRGNCKKASLGLVCEIGLRCRTYYVLCGSVLSVWTKVEGVLASVSGTNVKMQIVRLRTEDGQRIVGLIIPANCVSPLVNLLSTSDQSQQLAVQQKQLWQQHHPQSITNLSNL
What are the official names of this protein?
Protein strawberry notch homolog 1, mSno1.
What is the protein family that this protein belongs to?
Belongs to the SBNO family.
Protein: IBPB_YERP3
Sequence: MRNYDLSPLLRQWIGFDKLASTMQGGQEPQGFPPYNIEKTDDNHYRISLALAGFKQSELDIEVEGPRLTVRGKPTPVEKQVEYLHQGLVRKEFSLTFTLAEHLNVDNAQFENGLLHIDLLRQVPEALQPQRIAIGSATPQERQVLESPEAPDQQ
What is the function of this protein?
Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress.  Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE.  Its activity is ATP-independent.
What are the official names of this protein?
Small heat shock protein IbpB, 16 kDa heat shock protein B.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H4_PSAMI
Sequence: MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYCEHAKRKTVTAMDVVYALKRQGRTLYGFGG
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H4.
What is the protein family that this protein belongs to?
Belongs to the histone H4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: PYRH_GEOSL
Sequence: MGTPYYGRVLLKLSGEALAGDQGYGIDPRTITAIAAEIKEVVATGSQLALVIGGGNIFRGLAASSKGMDRASADYMGMLATMINSLAMQDALEKVGVDTRVQSAIAMQEVAEPYIRRRAIRHLEKGRIVIFGAGTGNPYFTTDTAASLRAMEIGADVILKGTKVDGVYSADPKKDPTAIKYPRLTYLEVLKKGLQVMDATATSLCMDNNLPIIVFDITTYGNIKKVVCGEEIGTIVKGE
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1983_SYNP2
Sequence: MASTNSFDVVSDFDRQEVVNTIDQALRDINTRYDLKDTKTTIELGENTITINTASDFTLDAVQTILVTKAVKRNLSPKLFDYGEAESASGGRVRQVITLRQGISKDDAKKITKMVKTDFKKVQASIQGDAVRISSKSKDDLQAVMQAVRDLDFPMPIQFTNYR
What are the official names of this protein?
UPF0234 protein SYNPCC7002_A1983.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: GGI3_STAHA
Sequence: MSKLVQAISDAVQAQQNQDWAKLGTSIVGIVENGVGILGKLFGF
What is the function of this protein?
Has hemolytic activity and also inhibits the growth of gonococci.
What are the official names of this protein?
Antibacterial protein 3, Gonococcal growth inhibitor III.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal hemolytic protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: ZN728_HUMAN
Sequence: MGSLTFRDVAIQFSLEEWQCLDTAQQNLYRNVMLENYRNLVFLGIAAPKPDLIIFLEQGKEPWNMKRHELVKEPPVICSHFAQDLWPEQGREDSFQKVILRRYEKCGHENLQLKIGCTNVDECKVHKKGYNKLNQSLTTTQSKVFQCGKYANIFHKCSNSKRHKIRHTGKKLLKCKEYVRSFCMLSHLSQHKRIYTRENSYKSEEHGKAFNWSSALTYKRIHTGEKPCKCEECGKAFSKFSILTKHKVIHTGEKHYKCEECGKAFTRSSSLIEHKRSHAGEKPYKCEECGKAFSKASTLTAHKTIHAGEKPYKCEECGKAFNRSSNLMEHKRIHTGEKPCKCEECGKAFGNFSTLTKHKVIHTGEKPYKCEECGKAFSWPSSLTEHKRIHAGDKPYKCEECGKTFKWSSTLTKHKIIHTGEKPYKCEECGKAFTTFSSLTKHKVIHTGEKHYKCEECGKVFSWSSSLTTHKAIHAGEKLYKCEECGKAFKWSSNLMEHKRIHTGEKPYKCEECGKAFSKVANLTKHKVIHTGEKQYKCEECGKAFIWSSRLSEHKRIHTGEKPYKCEECGKAFSWVSVLNKHKKIHAGKKFYKCEECGKDFNQSSHLTTHKRIHTGGKTLQM
What are the official names of this protein?
Zinc finger protein 728.