PharMolix/UniProtQA huggingface dataset:
Protein: RUN1_VITRO
Sequence: MASTSSSRASSSSSSSSTPSIPRTITYDVFLSFRGEDTRFNFTDHLYSALGRRGIRTFRDDKLRRGEAIAPELLKAIEESRSSVIVFSENYARSRWCLDELVKIMECHKDKKDPGHAVFPIFYHVDPSHVRKQEGSFGEAFAGYGENLKDKIPRWRTALTEAANLSGWPLQDGYESNQIKEITDSIFRRLKCKRLDAGANLVGIDSHVKEMIWRLHMESSDVRMVGMYGVGGIGKTTIAKVIYNELSREFEYMSFLENIREKFNTQGVSPLQNQLLDDILKGEGSQNINSVAHGASMIKDILSSKIVFIVLDDVDDQSQLEYLLRHREWLGEGSRVIITTRNKHVLDVQKVDDLYEVKGLNFEEACELFSLYAFEQNLPKSDYRNLSHRVVGYCQGLPLALKVLGCLLLKKTIPEWESELRKLDREPEAEILSVLKRSYDGLGRTEKSIFLDVACFFKGEDRDFVSKILDACDFHAEIGIKNLNDKCLITLQYNRIRMHDLIQQMGWEIVREKFPDEPNKWSRLWDTCDFERALTAYKGIKRVETISLDLSKLKRVCSNSNAFAKMTRLRLLKVQSSLDIDFEPEYIDADDKVELYDVVMKNASKMRLGRGFKFPSYELRYLRWDGYPLDFLPSNFDGGKLVELHLKCSNIKQLRLGNKDLEMLKVIDLSYSRKLSQMSEFSSMPNLERLFLRGCVSLIDIHPSVGNMKKLTTLSLKSCKKLKNLPDSIGDLESLEILDLAYCSKFEKFPEKGGNMKSLTELDLQNTAIKDLPDSIGDLESLKYLDLSDCSKFEKFPEKGGNMKSLRELDLRNTAIKDLPDSIRDLESLERLYLSYCSKFEKFPEKGGNMKSLMELDLQNTAIKDLPDSIGDLESLKYLDLSNCSKFEKFPEKGGNMKSLTELFLENTAIKDLPDSIGDLESLVSLNLSDCSKFEKFPEKGGNMKSLNWLYLNNTAIKDLPDSIGDLESLMRLYLSNSSKFEKLPEKVGNMKSLELLDLRNTAIKDLPDSIGDLEPLEKLSLSNCPKFEVLPLSLKAIDAHLCTSKEDLSRLLWLCHRNWLKSTTEEFDRWQLSAFIPESSGIPEWITYQNLGSEVTEKLPINWCEDPDFPGFVLSCLYRPSDYSSAYNFCHDFKCELNLHGNGFTFTDECSHSCWCDCHVNFKDSRDLVCVYWYPKTAIPEEDHHKYTHINASFTHRFEGHPFFCEDIKKIKCGINVIFLGDQRNHMPMLEHPQNSGDNGSALQDANGNVHGANQDDEHYHIPTLGLLGNFHDNGSAVLEDTLGNRKRRRDDSLPDVVEEPHYKKIGSHPTPISCFELHHQYQSEQNHMW
What is the function of this protein?
Disease resistance (R) protein that confers resistance to multiple powdery and downy mildew by promoting cell death (PubMed:24033846, PubMed:31439792).  Acts as a NAD(+) hydrolase (NADase): in response to activation, catalyzes cleavage of NAD(+) into ADP-D-ribose (ADPR) and nicotinamide; NAD(+) cleavage triggering a defense system that promotes cell death (PubMed:31439792).  Also able to hydrolyze NADP(+), but not other NAD(+)-related molecules (PubMed:31439792).
What are the official names of this protein?
Disease resistance protein RUN1, NAD(+) hydrolase RUN1, NADP(+) hydrolase RUN1, Resistance to Uncinula necator protein, MrRUN1.
What is the protein family that this protein belongs to?
Belongs to the disease resistance TIR-NB-LRR family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Localizes predominantly to the nucleus.
Protein: NUOB1_SYMTH
Sequence: MSADGVFRDQGGFVTTTVDSFLRWAQSNSIWPLTFGLACCAIEMMNLASGPRYDIARFGSEAFRASPRQADLIFISGRVSNKMAPVIKRVYSQMLEPKWVVAFGACASSGGIFDNYAIMQGVDNLLPVDIYVPGCPPTPEAVIYAVQKLRDRIRKEDPRGGIIVRG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B 1, NADH dehydrogenase I subunit B 1, NDH-1 subunit B 1.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NORV_SHIBS
Sequence: MSIVVKNNIHWVGQRDWEVRDFHGTEYKTLRGSSYNSYLIREEKNVLIDTVDHKFSREFVQNLRNEIDLADIDYIVINHAEEDHAGALTELMAQIPDTPIYCTANAIDSINGHHHHPEWNFNVVKTGDTLDIGNGKQLIFVETPMLHWPDSMMTYLTGDAVLFSNDAFGQHYCDEHLFNDEVDQTELFEQCQRYYANILTPFSRLVTPKITEILGFNLPVDMIATSHGVVWRDNPTQIVELYLKWAADYQEDRITIFYDTMSNNTRMMADAIAQGIAETDPRVAVKIFNVARSDKNEILTNVFRSKGVLVGTSTMNNVMMPKIAGLVEEMTGLRFRNKRASAFGSHGWSGGAVDRLSTRLQDAGFEMSLSLKAKWRPDQDALELCREHGREIARQWALAPLPQSTVNKVVKEETSATTTADLGPRMQCSVCQWIYDPAKGEPMQDVAPGTPWSEVPDNFLCPECSLGKDVFEELASEAK
What is the function of this protein?
Anaerobic nitric oxide reductase; uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes.  Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified.  NO probably binds to the di-iron center; electrons enter from the NorW at rubredoxin and are transferred sequentially to the FMN center and the di-iron center.  Also able to function as an aerobic oxygen reductase.
What are the official names of this protein?
Anaerobic nitric oxide reductase flavorubredoxin, FlRd, FlavoRb.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSI_BUCAP
Sequence: MKKDYKKVFLKNTKEERIKENSNYLRGTIIDDLKDEITNGFTGDNFSLIRFHGMYQDDRDLRLERNEQKLEPRYAMMLRCRLPRGIIKAKKWLKIDHFASKNTLYGTIRLNNLQTFQFHGILKKTLKDAHKMLNKIGLDSLGTANDVNRNVLCTSNPMESLIHQQCYEWVSKISNFLLPQTKAYAEIWLNQKKIATTDQEPILGKTYLPRKFKTTVVVPPYNDVDLYANDMNFIAITKNNKIVGFNVLIGGGLSINHGNKNTWPFLAVELGYITLEKTLSVAESIVTTQRDWGNRTDRKNAKTRYTIAKVGLSVFKKEVEKRANMTFETIKPYYFISRGDRFGWTKNINNDWSLTVFIQNGRIYDNDKQLVKSGLLKIANLHTGNFRLTANQNIVISEILDKNKKKIEEIAISHGLIKKVSSLRENSMACVSFPTCPLAIAESERILSFFITKVENIMLKYGIEKEIIILRISGCPNGCGRSLLAEIGLIGKSLGRYNLYIGGNRIGSRIPKIYKENITEQEILIHLDFLIKIWSIERQKKEHFGDFVIRRNVVKKVVNPIYDFWN
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Putative sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: Y4KS_SINFN
Sequence: MIPTERGLQQVLEWGRSLTGFADEHAAEAVRGGQYILQRIHPSLRDTSARTGRDPQDETLIVAFYRELALLFWLDDCNDLDLIAPEQLAAVEQALGQGVPCALPGFEGCAVLRASLAALAYDRRDYAQLLDDTRCYCAALRAGHAQAAGAAERWSYAEYLHNGIDSIAYANVFCCLSLLWGLDMATLRARPAFRQVLRLISAIGRLQNDLHGRDKDRSAGEADNAAILLLERYPAMPVVEFLNDELAGHTRMLHRVMAEERFPAPWGPLIEAMAAIRAHYYQTSTSRYRSDAAGGGQHAPA
What are the official names of this protein?
Uncharacterized protein y4kS.
Protein: FERN_AZOVI
Sequence: MALKIVESCVNCWACVDVCPSEAISLAGPHFEISASKCTECDGDYAEKQCASICPVEGAILLADGTPANPPGSLTGIPPERLAEAMREIQAR
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
Ferredoxin-like protein in nif region.
Protein: SAT5_ARATH
Sequence: MPPAGELRHQSPSKEKLSSVTQSDEAEAASAAISAAAADAEAAGLWTQIKAEARRDAEAEPALASYLYSTILSHSSLERSISFHLGNKLCSSTLLSTLLYDLFLNTFSSDPSLRNATVADLRAARVRDPACISFSHCLLNYKGFLAIQAHRVSHKLWTQSRKPLALALHSRISDVFAVDIHPAAKIGKGILLDHATGVVVGETAVIGNNVSILHHVTLGGTGKACGDRHPKIGDGCLIGAGATILGNVKIGAGAKVGAGSVVLIDVPCRGTAVGNPARLVGGKEKPTIHDEECPGESMDHTSFISEWSDYII
What are the official names of this protein?
Serine acetyltransferase 5, AtSAT-5, AtSERAT1;1, SAT-c.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAMT1_DICDI
Sequence: MEKTTPTQYDVKVQYNNSILNYAIDHSDQLTDIQKELIQFTKENIERHIMLTQAEQCSFFKLLIQVLNAKKTIDIGVFTGLSSLTAALAMGDEGRVVACDVSTDYTQHALKFWAKAGVDHKINLKIQPASKTLQELIDQGEENTYDFVFIDADKTGYDTYYELSLKLIRKGGIIAIDNVLQHGRVADPNANVEPNLVAIRALNDKILADKRVTKTMLPIADGITLVTKIN
What are the official names of this protein?
Probable caffeoyl-CoA O-methyltransferase 1, O-methyltransferase 5.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. CCoAMT subfamily.
Protein: SUS5_ARATH
Sequence: MEMTSGSLGNGIPEAMGQNRGNIKRCLEKYIENGRRVMKLNELMDEMEIVINDVTQRRRVMEGDLGKILCFTQAVVIPPNVAFAVRGTPGNWQYVKVNSSNLSVEALSSTQYLKLKEFLFDENWANDENALEVDFGALDFTLPWLSLSSSIGNGLSFVSSKLGGRLNDNPQSLVDYLLSLEHQGEKLMMNETLNTARKLEMSLILADVFLSELPKDTPFQAFELRFKECGFEKGWGESAGRVKETMRILSEILQAPDPQNIDRFFARVPRIFNVVIFSVHGYFGQTDVLGLPDTGGQVVYILDQVKALEDELLQRINSQGLNFKPQILVVTRLIPDAKKTKCNQELEPIFGTKYSNILRIPFVTENGILRRWVSRFDIYPYLERFTKDATTKILDILEGKPDLIIGNYTDGNLVASLMANKLGITQATIAHALEKTKYEDSDIKWKEFDPKYHFSSQFTADLISMNSADFIIASTYQEIAGSKERAGQYESHMSFTVPGLYRVVSGINVFDPRFNIAAPGADDSIYFPFTAQDRRFTKFYTSIDELLYSQSENDEHIGYLVDKKKPIIFSMARLDVVKNLTGLTEWYAKNKRLRDLVNLVIVGGFFDASKSKDREEISEIKKMHSLIEKYQLKGQFRWITAQTDRTRNGELYRSIADTRGAFVQPAHYEAFGLTVIEAMSCGLVTFATNQGGPAEIIVDGVSGFHIDPSNGEESSDKIADFFEKSGMDPDYWNMFSNEGLQRINECYTWKIYANKVINMGSTYSYWRHLNKDQKLAKQRYIHSFYNLQYRNLVKTIPILSDIPEPPPLPPKPLVKPSASKGSKRTQPRLSFRLFGA
What is the function of this protein?
Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways.  Functions in callose synthesis at the site of phloem sieve elements.
What are the official names of this protein?
Sucrose synthase 5, AtSUS5, Sucrose-UDP glucosyltransferase 5.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Plant sucrose synthase subfamily.
Protein: GTPB8_BOVIN
Sequence: MAAHRLRQSVGRLFAMGPELGSGRRAFSAFQAFTEVLRLPSKQLTKLVFPLEELHEHFVPGSRPDLHLNIFHPSLEDIARAESFFTASARNRIEYLTSAVRLDHAPDLHRPEVCFIGRSNVGKSSLIKALFSLAPEVEVRVSKKPGHTKKLNFYKVGKYFTLVDMPGYGYRAPEDFVDMVETYLKERKNLMRTFLLVDSVVGIQKADNIAIEMCEEFALPYVMVLTKIDKPSKGHLLKQVLQIQKFVDTKTQGCFPQLFPVSAMTYSGIHLLRCFIADITGNLKTTGF
What are the official names of this protein?
GTP-binding protein 8.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: YBEY_MYCSS
Sequence: MSIEVSNESGIDVSEEELISVARFVIEKMNVNPAAELSMVLLDTSSMADLHMRWMDLPGPTDVMSFPMDELEPGGRPDAPEPGPAMLGDIVLCPEFAAKQAETAGHSLGHELALLTVHGVLHLLGYDHAEPDEEKEMFALQRELLEEWVAHQVEAYHLDRQTERDRRLLDKSRYFDE
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_ECOLU
Sequence: MTQVAKKILVTCALPYANGSIHLGHMLEHIQADVWVRYQRMRGHEVNFICADDAHGTPIMLKAQQLGITPEQMIGEMSQEHQTDFAGFNISYDNYHSTHSEENRQLSELIYSRLKENGFIKNRTISQLYDPEKGMFLPDRFVKGTCPKCKSPDQYGDNCEVCGATYSPTELIEPKSVVSGATPVMRDSEHFFFDLPSFSEMLQAWTRSGALQEQVANKMQEWFESGLQQWDISRDAPYFGFEIPNAPGKYFYVWLDAPIGYMGSFKNLCDKRGDTTSFDEYWKKDSTAELYHFIGKDIVYFHSLFWPAMLEGSNFRKPTNLFVHGYVTVNGAKMSKSRGTFIKASTWLNHFDADSLRYYYTAKLSSRIDDIDLNLEDFVQRVNADIVNKVVNLASRNAGFINKRFDGVLASELADPQLYKTFTDAAEVIGEAWESREFGKAIREIMALADLANRYVDEQAPWVVAKQEGRDADLQAICSMGINLFRVLMTYLKPVLPKLTERAEAFLNTELTWHGIQQPLLGHKVNPFKALYNRIDMKQVEALVEASKEEVKAAATPVTGPLADDPIQETITFDDFAKVDLRVALIENAEFVEGSDKLLRLTLDLGGEKRNVFSGIRSAYPDPQALIGRHTIMVANLAPRKMRFGISEGMVMAAGPGGKDIFLLSPDAGAKPGHQVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_RHOPA
Sequence: MSLPEFSMRQLLEAGVHFGHQSHRWNPKMADYIFGVRNNIHIVDLTQTVPLLHRALQAISDTVAKGGRVLFVGTKRQAQDAVADAAKRSAQYFVNSRWLGGTLTNWKTISGSIRRLRHLEDVLSSADANAYTKKERLELQRERDKLNRSLGGIKDMGGLPDLIFVIDTNKEDIAIQEAQRLGIPVAAIVDTNCDPKGITYLVPGNDDAGRAIALYCDLVARAVIDGISRAQGDVGIDIGAAAQPLREDLPAAQATTFQGLPGPRGTPDDLKKLPGVSGAIEKKFNDLGIFHFWQLAELDQATAHQIGEELGLPSRADAWVAQAKSLTAEAE
What are the official names of this protein?
30S ribosomal protein S2, RRP-S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RL28_PORG3
Sequence: MSKICQITGKKAMVGNNVSHSKRRTKRVFDVNLFRKKFYWVEQDCWVVLRISAAGLRLINKIGLDAAIKRAAEKGFLNA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: PURL_MYCTO
Sequence: MSPLARTPRKTSVLDTVEHAATTPDQPQPYGELGLKDDEYRRIRQILGRRPTDTELAMYSVMWSEHCSYKSSKVHLRYFGETTSDEMRAAMLAGIGENAGVVDIGDGWAVTFKVESHNHPSYVEPYQGAATGVGGIVRDIMAMGARPVAVMDQLRFGAADAPDTRRVLDGVVRGIGGYGNSLGLPNIGGETVFDPCYAGNPLVNALCVGVLRQEDLHLAFASGAGNKIILFGARTGLDGIGGVSVLASDTFDAEGSRKKLPSVQVGDPFMEKVLIECCLELYAGGLVIGIQDLGGAGLSCATSELASAGDGGMTIQLDSVPLRAKEMTPAEVLCSESQERMCAVVSPKNVDAFLAVCRKWEVLATVIGEVTDGDRLQITWHGETVVDVPPRTVAHEGPVYQRPVARPDTQDALNADRSAKLSRPVTGDELRATLLALLGSPHLCSRAFITEQYDRYVRGNTVLAEHADGGMLRIDQSTGRGIAVSTDASGRYTLLDPYAGAQLALAEAYRNVAVTGATPVAVTNCLNFGSPEDPGVMWQFTQAVRGLADGCADLGIPVTGGNVSFYNQTGSAAILPTPVVGVLGVIDDVRRRIPTGLGAEPGETLMLLGDTRDEFDGSVWAQVTADHLGGLPPVVDLAREKLLAAVLSSASRDGLVSAAHDLSEGGLAQAIVESALAGETGCRIVLPEGADPFVLLFSESAGRVLVAVPRTEESRFRGMCEARGLPAVRIGVVDQGSDAVEVQGLFAVSLAELRATSEAVLPRYFG
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAR2_AUSRA
Sequence: SDYLQLAR
What is the function of this protein?
FMRFamides and FMRFamide-like peptides are neuropeptides.
What are the official names of this protein?
Extended FMRFamide-2, FMRFa-2.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRF amide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: HV349_HUMAN
Sequence: MEFGLSWVFLVAILKGVQCEVQLVESGGGLVQPGRSLRLSCTASGFTFGDYAMSWVRQAPGKGLEWVGFIRSKAYGGTTEYAASVKGRFTISRDDSKSIAYLQMNSLKTEDTAVYYCTR
What is the function of this protein?
V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170).
What are the official names of this protein?
Immunoglobulin heavy variable 3-49.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: SEPF3_STRAW
Sequence: MGSVRKASAWLGLVDDNDDERYYDDDYAEGQESGEAWVTDPRVKVASETAEEKGRRIGTVTPDSFRDARGIGELFRDGVPVIINLTAMEPTDAKRVVDFAAGLTFGLRGTIERVATRVFLLTPANTEIVSGEAAGRPTDGFFNQS
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF 3.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: OBG_NITHX
Sequence: MKFLDEAKVYIRSGDGGNGCVAFRREKFIEFGGPSGGNGGRGGDVIVEVADGLNTLIDYRYQQHFKAPKGTNGMGSDRHGANGKAIVLKVPLGTQIIDEDRETLIHDFTTVGERFVLAEGGNGGFGNAHFKSSTNRAPRNANPGQPGEERWIWLRLKLIADAGLVGLPNAGKSTFLSKVSAAKPKIADYPFTTLHPQLGVVNAGDREFVLADIPGLIEGAHEGTGLGDRFLGHVERCRVLLHLVDATCEHAGKAYKTVRGELEAYAGTLAEKVEIVALNKIDAVSVEDLKKQRDRLKRAANKMPLLLSGITGKGVPEVLQTLAAVIGEAPVSDKAKGAGASAAQAVVPPVAQAKPWSP
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATA_METBU
Sequence: MEVNGEIYRVAGPVVTVIGIKPRMYDVVKVGHEGLMGEVIRIKGEQATVQVYEDTSGLKPGEPVMNTGLPLSVELGPGLLESIYDGIQRPLPVLQEKMGNFIQRGVTANGLDRERVWEFKPTVSKGDEVKGGNILGLVQETKNIEHKIMVPPSISGTIKEIKAGSFKVDETICVLTDGTEISMMQKWPVRGPRPVAKKLMPTKPLITGQRILDGMFPIAKGGTAAIPGPFGSGKTVTQQQLAKWSDTDIVVYIGCGERGNEMADVLNEFPELEDPKTGRPLMERTVLIANTSNMPVAAREASVYTGITIAEYYRDMGYDVSLMADSSSRWAEAMREISSRLEEMPGEEGYPAYLSARLSEFYERAGAVNSLAGLDGSITVIGAVSPPGGDFSEPVTQNTLRIVKVFWALDAKLSQRRHFPSINWLTSYSLYTQGLADWYSENVGADWTQLRDDAMDLLQQESELQEIVQLVGSDALPEDQQLTLEVARMVREYFLQQNAFHPVDTYCPFDKQYKLLKSITRYGELATAALESGVPMNKIITIKSKDELAKVKFEENFDAALDVVMKKMDEEFAQIGGN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The archaeal alpha chain is a catalytic subunit.
What are the official names of this protein?
V-type ATP synthase alpha chain, V-ATPase subunit A.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: HBB_BUBBU
Sequence: MLTAEEKAAVTAFWGKVHVDEVGGEALGRLLVVYPWTQRFFESFGDLSTADAVMNNPKVKAHGKKVLDSFSNGMKHLDDLKGTFAALSELHCDKLHVDPENFKLLGNVLVVVLARHFGKEFTPVLQADFQKVVAGVANALAHRYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RS16_ORITB
Sequence: MAVKIRLARSGAKKCAYFKIVIANNCSPRDGAFIEKVGHYNPMLPKDNHERVILKTDRIEHWLSHGAQPTEKVINFLQQFSITLPLAIQKKHNIKLKNYVAKPSKKSK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: GATB_PROM1
Sequence: MSESNVSWEVVIGLETHVQLGTKSKIFTSASTTFGDDPNTHIDPVVCGLPGTLPVLNKKVLEYAVKAAMALNLNIASHSKFDRKQYFYPDLPKNYQISQFDEPIAEDGWIEVEVAEKGKETYVKKIGIERLHMEEDAGKLVHAGSDQLSGSTHSLVDYNRAGVALAEIVSKPDLRTGREAAEYAAEVRRIMRYLGVSDGNMQEGSLRCDVNISVRPTINDPFGTKVEIKNMNSFSAIQKACEYEIKRQIKAYESGEEVKQETRLWDEGKQLTKSMRSKEGSSDYRYFPDPDLGPIEVSNELKEKWRSELPELPAAKRNRYSTELGLSIYDARVLTDESSMATYFEKVVNEGGAAKSSANWITGDLAAYINSNRLTFDQLHFQPSELAEMLKMIDTGEISGKIAKEILPELLSKGGSPKQLVQERGLGMIGDPKVIEEIIDQLILKHPNEVESFRSGKKKLLGFFVGQLMKETKGKADPKLANQILNKKLQG
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: RL9_HUMAN
Sequence: MKTILSNQTVDIPENVDITLKGRTVIVKGPRGTLRRDFNHINVELSLLGKKKKRLRVDKWWGNRKELATVRTICSHVQNMIKGVTLGFRYKMRSVYAHFPINVVIQENGSLVEIRNFLGEKYIRRVRMRPGVACSVSQAQKDELILEGNDIELVSNSAALIQQATTVKNKDIRKFLDGIYVSEKGTVQQADE
What is the function of this protein?
Component of the large ribosomal subunit (PubMed:23636399, PubMed:32669547).  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399, PubMed:32669547).
What are the official names of this protein?
60S ribosomal protein L9, Large ribosomal subunit protein uL6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_MYCS2
Sequence: MNTLDFVDQASLRDDIPTFSPGDTVNVHVKVIEGSKERIQVFKGVVIRRQGGGISETFTVRKESYGVGVERTFPVHSPNIDHIDVLTRGDVRRAKLYYLRELRGKKAKIKEKR
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: RS3_RHILO
Sequence: MGQKVNPIGLRLGINRTWDSRWFANTGEYGKLLHEDIKIRKYLEKELKQAAISKVVIERPHKKCRVTIHAARPGLIIGKKGADIEKLRKKLMEMTKSETHLNIVEVRKPEIDATLVAQSIAQQLERRIAFRRAMKRAVQSAMRLGAEGIRINCSGRLGGAEIARMEWYREGRVPLHTLRADVDYGTAEANTAYGICGVKVWVFKGEILEHDPMASERRATEGDAAHGGGGDRERGRRRENA
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: NU1M_ALBCA
Sequence: MVVFKSLLLNLCILLSVAFYTLLERKVLSSMQIRKGPNKVGLYGIIQPIADALKLFLKEFFIPVNSNSFMFMILPLLGLTLSLMLWAVFPSMWMFNFHSYLLMLFVALTGTFVYVIIFAGWSSNSKYSFLGGMRAAAQTISYEVSMLLLLFFAVLMYRTYSWYEAGLSSPIGIIIFIIMFIWFASCLAETNRAPFDFAEGESELVSGFNIEYYGGMFALLFLAEYSSILFMCMMSTVWFLYSDMIFIMTLLILLIAMAFLFARGVYPRHRYDLLMNLCWKSFLPFSLCCICYSMLLWIV
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ISPF_PSE14
Sequence: MRIGHGYDVHRFAEGDFITLGGVRIAHGFGLLAHSDGDVLLHALSDALLGAAALGDIGKHFPDTDPQFKGADSRVLLRHVLKQIHGKGWKVGNVDATIVAQAPKMAPHIDAMRALIAEDLQVELDQVNVKATTTEKLGFTGREEGIAVHAVALLLRA
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.