PharMolix/UniProtQA huggingface dataset:
Protein: RIMO_HELPS
Sequence: MQIKENKQLCLISLGCSKNLVDSEVMLGKLYNYTLTNDTKSADVILINTCGFIESAKQESIQTILNAAKDKKKGAILIASGCLSERYKDEIKELIPEVDIFTGVGDYDKIDIMIAKKQNQFSEQVFLSEHYNARIITGSSVHAYVKISEGCNQKCSFCAIPSFKGKLQSRELDSILKEAENLALKGYTDMTFIAQDSSSFLYDKGQKDGLIQLISAIDKQQALKSARILYLYPSSTTLELISTIESSPIFQNYFDMPIQHISDSMLKKMRRNSSQAHHLKLLDAMKQVKESFIRSTIIVGHPEENEGEFEELSAFLDEFRFDRLNIFAFSAEENTHAYSLEKVPKKIINARIKALNKIALKHQNNSFKALLNKPIKALVENKEGEYFYKARDLRWAPEVDGEILINDSELATPLKPGHYTIMPSAFKDNILLAKVLSPF
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELD_ECO24
Sequence: MSENSIRLTQYSHGAGCGCKISPKVLETILHSEQAKFVDPNLLVGNETRDDAAVYDLGNGTSVISTTDFFMPIVDNPFDFGRIAATNAISDIFAMGGKPIMAIAILGWPINKLSPEIAREVTEGGRYACRQAGIALAGGHSIDAPEPIFGLAVTGIVPTERVKKNSTAQAGCKLFLTKPLGIGVLTTAEKKSLLKPEHQGLATEVMCRMNIAGASFANIEGVKAMTDVTGFGLLGHLSEMCQGAGVQARVDYDAIPKLPGVEEYIKLGAVPGGTERNFASYGHLMGEMPREVRDLLCDPQTSGGLLLAVMPEAENEVKTTAAEFGIELTAIGELVPARGGRAMVEIR
What is the function of this protein?
Synthesizes selenophosphate from selenide and ATP.
What are the official names of this protein?
Selenide, water dikinase, Selenium donor protein, Selenophosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the selenophosphate synthase 1 family. Class I subfamily.
Protein: DAPF_BURMA
Sequence: MKLSFTKMHGAGNDFVVLDGYTRALPPLTGAQVRALADRHFGIGADQLLLVEKPTVDGADFKYRIFNCDGGEVEHCGNGARCFVKFVRDHGLTGKASVRVEVKHGVITLTMQDNGEVVVDMGAPVFEPARVPFDASGLDGRREGADTLWPLPVNGVTRWISVVSMGNPHAVQIVDDAEAFAVRVDGPAIERDPRFPQRVNAGFMQIVSRHEVNLRVYERGAGETLACGTGACAAVAAGIRRGRLDSPVTVHTHGGTLTISWNGACDERAPLMMAGPATTVFEGVIELPA
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1759_STAAC
Sequence: MITYKNILIAVDGSHEAEWAFNRAVGVAKRNDAKLTIVNVIDSRTYSSYEVYDAQFTEKSKHFAEELLNGYKEVATNAGVKDVETRLEFGSPKSIIPKKLAHEINADLIMSGTSGLNAVERFIVGSVSESIVRHAPCDVLVVRTEELPADFQPQVATTQLREKYQN
What are the official names of this protein?
Putative universal stress protein SACOL1759.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTRC_SALTY
Sequence: MQRGIVWVVDDDSSIRWVLERALAGAGLTCTTFENGNEVLAALASKTPDVLLSDIRMPGMDGLALLKQIKQRHPMLPVIIMTAHSDLDAAVSAYQQGAFDYLPKPFDIDEAVALVERAISHYQEQQQPRNIEVNGPTTDMIGEAPAMQDVFRIIGRLSRSSISVLINGESGTGKELVAHALHRHSPRAKAPFIALNMAAIPKDLIESELFGHEKGAFTGANTIRQGRFEQADGGTLFLDEIGDMPLDVQTRLLRVLADGQFYRVGGYAPVKVDVRIIAATHQNLERRVQEGKFREDLFHRLNVIRIHLPPLRERREDIPRLARHFLQVAARELGVEAKLLHPETETALTRLAWPGNVRQLENTCRWLTVMAAGQEVLIQDLPGELFEASTPDSPSHLPPDSWATLLAQWADRALRSGHQNLLSEAQPELERTLLTTALRHTQGHKQEAARLLGWGRNTLTRKLKELGME
What is the function of this protein?
Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation.  Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.
What are the official names of this protein?
DNA-binding transcriptional regulator NtrC, Nitrogen regulation protein NR(I), Nitrogen regulator I, NRI.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DGCC_ECOL6
Sequence: MFPKIMNDENFFKKAAAHGEEPPLTPQNEHQRSGLRFARRVRLPRAVGLAGMFLPIASTLVSHPPPGWWWLVLVGWAFVWPHLAWQIASRAVDPLSREIYNLKTDAVLAGMWVGVMGVNVLPSTAMLMIMCLNLMGAGGPRLFVAGLVLMVVSCLVTLELTGITVSFNSAPLEWWLSLPIIVIYPLLFGWVSYQTATKLAEHKRRLQVMSTRDGMTGVYNRRHWETMLRNEFDNCRRHNRDATLLIIDIDHFKSINDTWGHDVGDEAIVALTRQLQITLRGSDVIGRFGGDEFAVIMSGTPAESAITAMLRVHEGLNTLRLPNTPQVTLRISVGVAPLNPQMSHYREWLKSADLALYKAKKAGRNRTEVAA
What is the function of this protein?
A probable diguanylate cyclase.
What are the official names of this protein?
Probable diguanylate cyclase DgcC, DGC.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL24_CLOBB
Sequence: MKVHVRKSDTVVVISGKDKGKTGEVLKVYPKTGKVLVQGINIVKKHQKANKSQVESAIIEREAAINSSKVMLYCNKCKNATRIASKILDDGTKVRVCKKCSETF
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: FDHD_ECOLI
Sequence: MKKTQRKEIENVTNITGVRQIELWRRDDLQHPRLDEVAEEVPVALVYNGISHVVMMASPKDLEYFALGFSLSEGIIESPRDIFGMDVVPSCNGLEVQIELSSRRFMGLKERRRALAGRTGCGVCGVEQLNDIGKPVQPLPFTQTFDLNKLDDALRHLNDFQPVGQLTGCTHAAAWMLPSGELVGGHEDVGRHVALDKLLGRRSQEGESWQQGAVLVSSRASYEMVQKSAMCGVEILFAVSAATTLAVEVAERCNLTLVGFCKPGRATVYTHPQRLSN
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity (PubMed:3077634, PubMed:8522521, PubMed:22194618, PubMed:25649206).  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.  Specifically interacts with IscS and stimulates its cysteine desulfurase activity.  Also binds the molybdenum cofactor (PubMed:22194618, PubMed:25649206).  Required for activity of formate dehydrogenase N (FDH-N), formate dehydrogenase O (FDH-O) and formate dehydrogenase H (FDH-H) (PubMed:3077634, PubMed:8522521, PubMed:22194618).
What are the official names of this protein?
Sulfur carrier protein FdhD, Sulfurtransferase FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUFE_SALPB
Sequence: MAALPDKEKLLRNFTRCANWEEKYLYIIELGQRLAELNPQDRNPQNTIHGCQSQVWIVMRRNANGIIELQGDSDAAIVKGLMAVVFILYHQMTAQDIVHFDVRPWFEKMALTQHLTPSRSQGLEAMIRAIRAKAATLS
What is the function of this protein?
Participates in cysteine desulfuration mediated by SufS.  Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules.  Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process.
What are the official names of this protein?
Cysteine desulfuration protein SufE.
What is the protein family that this protein belongs to?
Belongs to the SufE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1496_MYCBO
Sequence: MTLTPEASKSVAQPPTQAPLTQEEAIASLGRYGYGWADSDVAGANAQRGLSEAVVRDISAKKNEPDWMLQSRLKALRIFDRKPIPKWGSNLDGIDFDNIKYFVRSTEKQAASWDDLPEDIRNTYDRLGIPEAEKQRLVAGVAAQYESEVVYHQIREDLEAQGVIFLDTDTGLREHPDIFKEYFGTVIPAGDNKFSALNTAVWSGGSFIYVPPGVHVDIPLQAYFRINTENMGQFERTLIIADEGSYVHYVEGCLPAGELITTADGDLRPIESIRVGDFVTGHDGRPHRVTAVQVRDLDGELFTFTPMSPANAFSVTAEHPLLAIPRDEVRVMRKERNGWKAEVNSTKLRSAEPRWIAAKDVAEGDFLIYPKPKPIPHRTVLPLEFARLAGYYLAEGHACLTNGCESLIFSFHSDEFEYVEDVRQACKSLYEKSGSVLIEEHKHSARVTVYTKAGYAAMRDNVGIGSSNKKLSDLLMRQDETFLRELVDAYVNGDGNVTRRNGAVWKRVHTTSRLWAFQLQSILARLGHYATVELRRPGGPGVIMGRNVVRKDIYQVQWTEGGRGPKQARDCGDYFAVPIKKRAVREAHEPVYNLDVENPDSYLAYGFAVHNCTAPIYKSDSLHSAVVEIIVKPHARVRYTTIQNWSNNVYNLVTKRARAEAGATMEWIDGNIGSKVTMKYPAVWMTGEHAKGEVLSVAFAGEDQHQDTGAKMLHLAPNTSSNIVSKSVARGGGRTSYRGLVQVNKGAHGSRSSVKCDALLVDTVSRSDTYPYVDIREDDVTMGHEATVSKVSENQLFYLMSRGLTEDEAMAMVVRGFVEPIAKELPMEYALELNRLIELQMEGAVG
What are the official names of this protein?
UPF0051 protein Mb1496.
What is the protein family that this protein belongs to?
Belongs to the UPF0051 (ycf24) family.
Protein: KLDC9_MOUSE
Sequence: MAGVQTLGRARGSTWTWRPVARDVLLARAFHSCTELEGRFYLVGGLLEGGARVPSNDTVIFDPAVGQAVRLVARGSPLRSHHDAALVGGRWLCVVGGWDGSRRLSTVAALDTEREVWEAWAANPGNCPPAGLSSHTCTRLSDGELRVSGREGGTHTQRRYGSIYTLKLDHRTRTYCYKEEGCHTTSRSGHCAALLPTAGPHPGHQLLLFGGCNSVGPEVAGQWSPGKIKEEQPVAPHLREQLARLVSSGQGLQQGPQSLRHHSCSVVGPFAVLFGGETLTRARDTICNDLYIYDTRKSPPLWFHFPSTDRGLKRVGHRTCLWNDQLYLVGGFGEDGRTASPQVCILEFFI
What are the official names of this protein?
Kelch domain-containing protein 9.
Protein: G6PIP_ARATH
Sequence: MASLSGLYSSSPSLKPAKNHSFKALPAQSRDSFSFPHTSKPTNLPLTLSSARSVARDISHADSKKELLKDPDALWKRYLDWFYQQKELGLYLDISRVGFTDEFVAEMEPRFQAAFKAMEDLEKGSIANPDEGRMVGHYWLRNSKLAPKPTLKTLIENTLDSICAFSDDIISGKIKPPSSPEGRFTQILSVGIGGSALGPQFVAEALAPDNPPLKIRFIDNTDPAGIDHQIAQLGPELASTLVVVISKSGGTPETRNGLLEVQKAFREAGLNFAKQGVAITQENSLLDNTARIEGWLARFPMYDWVGGRTSIMSAVGLLPAALQGINVREMLTGAALMDEATRTTSIKNNPAALLAMCWYWASNGVGSKDMVVLPYKDSLLLFSRYLQQLVMESLGKEFDLDGNTVNQGLTVYGNKGSTDQHAYIQQLRDGVHNFFATFIEVLRDRPPGHDWELEPGVTCGDYLFGMLQGTRSALYANGRESISVTIQEVTPTSVGAIIALYERAVGLYASIVNINAYHQPGVEAGKKAAAEVLALQKRVLSVLNEATCKDPVEPLTLEEIADRCHAPEEIEMIYKIIAHMSANDRVLIAEGNCGSPRSIKVYLGECNVDDLYA
What is the function of this protein?
Promotes the synthesis of starch in leaves.
What are the official names of this protein?
Glucose-6-phosphate isomerase 1, chloroplastic, GPI 1, Phosphoglucose isomerase 1, PGI 1, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: PELP1_MOUSE
Sequence: MAAAVLSGASAGSPAGAPGGPGGLSAVGSGPRLRLLLLESISGLLQPRTASPVAPVHPPIQWAPHLPGLMCLLRLHGTAGGAQNLSALGALVNLSNAHLGSIKTRFEGLCLLSLLIGESPTELFQQHCVSWLRSIQQVLQSQDSPSTMELAVAVLRDLLRHASQLPTLFRDISTNHLPGLLTSLLGLRPECEQSALEGMKACVTYFPRACGSLKGKLASFFLSRLDSLNPQLQQLACECYSRLPSLGAGFSQGLKHTENWEQELHSLLTSLHSLLGSLFEETEPAPVQSEGPGIEMLLSHSEDGNTHVLLQLRQRFSGLARCLGLMLSSEFGAPVSVPVQEILDLICRILGISSKNINLLGDGPLRLLLLPSLHLEALDLLSALILACGSRLLRFGALISRLLPQVLNAWSTGRDTLAPGQERPYSTIRTKVYAILELWVQVCGASAGMLQGGASGEALLTHLLSDISPPADALKLCSTRGSSDGGLQSGKPSAPKKLKLDMGEALAPPSQRKGDRNANSDVCAAALRGLSRTILMCGPLIKEETHRRLHDLVLPLVMSVQQGEVLGSSPYNSSCCRLGLYRLLLALLLAPSPRCPPPLACALKAFSLGQWEDSLEVSSFCSEALVTCAALTHPRVPPLQSSGPACPTPAPVPPPEAPSSFRAPAFHPPGPMPSIGAVPSTGPLPSAGPIPTVGSMASTGQVPSRPGPPATANHLGLSVPGLVSVPPRLLPGPENHRAGSGEDPVLAPSGTPPPSIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPSLPPAPPSGTPPPAAPAGPPTASPPVPAKEDSEELPATPGPPPPPPPPPPPASGPVTLPPPQLVPEGTPGGGGPTAMEEDLTVININSSDEEEEEEEEEEEEDEDEEEEDFEEEEEDEEEYFEEEEEEEEFEEEFEEEEGELEEEEEEEEEELDEVEDVEFGSAGEVEEGGPPPPTLPPALPPSDSPKVQPEAEPEPGLLLEVEEPGPEEVPGPETAPTLAPEVLPSQEEGEQEVGSPAAGPPQELVEESSAPPALLEEGTEGGGDKVPPPPETPAEEMETEAEVPAPQEKEQDDTAAMLADFIDCPPDDEKPPPATEPDS
What is the function of this protein?
Coactivator of estrogen receptor-mediated transcription and a corepressor of other nuclear hormone receptors and sequence-specific transcription factors.  Plays a role in estrogen receptor (ER) genomic activity when present in the nuclear compartment by activating the ER target genes in a hormonal stimulation dependent manner.  Can facilitate ER non-genomic signaling via SRC and PI3K interaction in the cytosol.  Plays a role in E2-mediated cell cycle progression by interacting with RB1.  May have important functional implications in ER/growth factor cross-talk.  Interacts with several growth factor signaling components including EGFR and HRS.  Functions as the key stabilizing component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes (PubMed:22872859).  Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit.  Regulates pre-60S association of the critical remodeling factor MDN1 (By similarity).
What are the official names of this protein?
Proline-, glutamic acid- and leucine-rich protein 1, Modulator of non-genomic activity of estrogen receptor.
What is the protein family that this protein belongs to?
Belongs to the RIX1/PELP1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Nucleus. Cytoplasm. Note=Mainly found in the nucleoplasm, with low levels detected in the cytoplasm. Also found associated with the plasma membrane.
Protein: NCS2_PAPSO
Sequence: MSKLITTEPLKSMAEVISNYVIQRESFSARNILNKNSLVKKEIRYDLEVPTSADSIWSVYSCPDIPRLLRDVLLPGVFQKLDVIEGNGGVGTVLDIVFPPGAVPRSYKEKFVNINHEKRLKEVIMIEGGYLDMGCTFYMDRIHIFEKTPNSCVIESSIIYEVKEEYAGKMAKLITTEPLESMAEVISGYVLKKRLQVFGFEIKPKLRFNLLLCLIICLVIAGGMFVAGVPL
What is the function of this protein?
Involved in the biosynthesis of (S)-coclaurine, the common precursor of all benzylisoquinoline alkaloids such as morphine, sanguinarine, codeine or papaverine.  Condenses dopamine and 4-hydroxyphenylacetaldehyde.
What are the official names of this protein?
S-norcoclaurine synthase 2, PsNCS2.
What is the protein family that this protein belongs to?
Belongs to the BetVI family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Vacuole membrane; Single- pass membrane protein. Note=Initially localized to the endoplasmic reticulum but subsequently sorted to the vacuole.
Protein: FHL1_RAT
Sequence: MSEKFDCHYCRDPLQGKKYVQKDGRHCCLKCFDKFCANTCVECRKPISADAKEVHYKNRYWHDTCFRCAKCLHPLASETFVSKDGKILCNKCATREDSPRCKGCFKAIVAGDQNVEYKGTIWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWHAECFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHNEQVYCPDCAKKL
What is the function of this protein?
May have an involvement in muscle development or hypertrophy.  Isoform 2 binds to RBP-J and plays a negative regulatory role in the RBP-J-mediated transcription in mammalian systems (By similarity).
What are the official names of this protein?
Four and a half LIM domains protein 1, FHL-1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YTFE_SALEP
Sequence: MAYRDQPLGELALSIPRASALFRQYDMDYCCGGKQTLARAAARHDVDIDIIEAQLAQLAEQPIEKDWRAVPLADIIDHIVVRYHDRHREQLPELILQATKVERVHADKPNVPRGLTKYLTALHEELSSHMMKEEQILFPMIKQGMGRQATGPISVMESEHDEAGELVDVIKHVTQNVTPPPEACTTWKAMYNGINEMIDDLMEHISLENNVLFPRALAGE
What is the function of this protein?
Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions.
What are the official names of this protein?
Iron-sulfur cluster repair protein YtfE.
What is the protein family that this protein belongs to?
Belongs to the RIC family. YtfE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCDBA_HUMAN
Sequence: MAVRELCFPRQRQVLFLFLFWGVSLAGSGFGRYSVTEETEKGSFVVNLAKDLGLAEGELAARGTRVVSDDNKQYLLLDSHTGNLLTNEKLDREKLCGPKEPCMLYFQILMDDPFQIYRAELRVRDINDHAPVFQDKETVLKISENTAEGTAFRLERAQDPDGGLNGIQNYTISPNSFFHINISGGDEGMIYPELVLDKALDREEQGELSLTLTALDGGSPSRSGTSTVRIVVLDVNDNAPQFAQALYETQAPENSPIGFLIVKVWAEDVDSGVNAEVSYSFFDASENIRTTFQINPFSGEIFLRELLDYELVNSYKINIQAMDGGGLSARCRVLVEVLDTNDNPPELIVSSFSNSVAENSPETPLAVFKINDRDSGENGKMVCYIQENLPFLLKPSVENFYILITEGALDREIRAEYNITITVTDLGTPRLKTEHNITVLVSDVNDNAPAFTQTSYTLFVRENNSPALHIGSVSATDRDSGTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAFEFRVGATDRGSPALSREALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSATATLHLLLVDGFSQPYLPLPEAAPAQAQAEADLLTVYLVVALASVSSLFLLSVLLFVAVRLCRRSRAASVGRCSVPEGPFPGHLVDVRGAETLSQSYQYEVCLTGGPGTSEFKFLKPVISDIQAQGPGRKGEENSTFRNSFGFNIQ
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.  May be involved in the establishment and maintenance of specific neuronal connections in the brain.
What are the official names of this protein?
Protocadherin beta-10, PCDH-beta-10.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: LIPA1_NOSS1
Sequence: MTVKPDWLRVKAPQWERVGNVKEILRDLALNTVCEEASCPNIGECFQAGTATFLIMGPACTRACPYCDIDFEKKPKALDPTEPTRLAEAVRRMRLNHVVITSVNRDDLPDGGASQFVKCIAEVRAVSPQTTIEVLIPDLCGNWEALRIILQASPEVLNHNTETIPRLYRRVRPQGNYDRTLELLQRSRQIAPWLYTKSGIMVGLGETNAEVRQVMQDLRAVDCDILTIGQYLQPSQKHLQVNDFVTPEQFAAWQVYGEELGFLQVVSSPLTRSSYHAEQVRQLMERYPRNK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase 1, Lip-syn 1, LS 1, Lipoate synthase 1, Lipoic acid synthase 1, Sulfur insertion protein LipA 1.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: O168_CONST
Sequence: MKLTCMMIVAVLFLTAWTFVTADDSRNGLKNLFPKARHEMKNPDASKLNKRDGCSNAGGFCGIHPGLCCSEICLVWCT
What is the function of this protein?
Delta-conotoxins bind to site 6 of voltage-gated sodium channels (Nav) and inhibit the inactivation process.
What are the official names of this protein?
Delta-conotoxin-like S6.8.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LURA1_RAT
Sequence: MEGTAESQTPDLRDVEGKVGRKTPEGLLRGLRGECDLGTSGDVLLPGASSTGHGLGDKIMALRMELAYLRAIDVKILQQLVTLNEGIEAVRWLLEERGTLTSHCSSLTSSQYSLTGGSPERSRRGSWDSLPDTSSTDRLDSVSIGSFLDTVAPRELDEQGHPGPSCPEIDWAKVIPSEDRARTEVDMTSTKLGSLTATWKLPGDGLQCGPPEPSEDDSAKQGFEAHWYWGQCQDDVTFL
What is the function of this protein?
Acts as an activator of the canonical NF-kappa-B pathway and drive the production of pro-inflammatory cytokines.  Promotes the antigen (Ag)-presenting and priming function of dendritic cells via the canonical NF-kappa-B pathway (By similarity).  In concert with MYO18A and CDC42BPA/CDC42BPB, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration.  Activates CDC42BPA/CDC42BPB and targets it to actomyosin through its interaction with MYO18A, leading to MYL9/MLC2 phosphorylation and MYH9/MYH10-dependent actomyosin assembly in the lamella.
What are the official names of this protein?
Leucine rich adaptor protein 1, Leucine repeat adapter protein 35A.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRD_PONAB
Sequence: MAAMASLGALALLLLSSLSRCSAEACLEPQITPSYYTTSDAVISTETVFIVEISLTCKNRVQNMALYADVGGKQFPVTRGQDVGRYQVSWSLDHKSAHAGTYEVRFFDEESYSLLRKAQRNNEDISIIPPLFTVSVDHRGTWNGPWVSTEVLAAAIGLVIYYLAFSAKSHIQA
What is the function of this protein?
TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.
What are the official names of this protein?
Translocon-associated protein subunit delta, TRAP-delta, Signal sequence receptor subunit delta, SSR-delta.
What is the protein family that this protein belongs to?
Belongs to the TRAP-delta family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: RSMH_SERP5
Sequence: MLENYKHTTVLLDEAVNGLNIRSNGTYIDGTFGRGGHSRLILSQLGPEGRLLAIDRDPQAIAAAKSIEDPRFSIVHGPFSDLSHYVRERELVGQIDGILLDLGVSSPQLDDAERGFSFMRDGPLDMRMDSSSGQSASEWLMKAEADDIAWVLKTFGEERFAKRIARAIVERNQVDPMTRTKQLADLIANASPFRDKHKHPATRSFQAIRIYINSELEEIERALDGALEVLAPQGRLSVISFHSLEDRIVKRFMRHHSRGAQVPAGIPLTEAQLRSMGGRTLKALGKMMPGDAEVAENPRARSSVLRIAERMPT
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLNE_ECO57
Sequence: MKPLSSPLQQYWQTIVERLPEPLAEESLSAQAKSVLTFSDFVQDSISAHPEWLTELESQPPQADEWQHYVAWLQEALINVSDEAGLMRELRLFRRRIMVRIAWAQTLALVTEESILQQLSYLAETLIVAARDWLYDACCREWGTPCNAQGEAQPLLILGMGKLGGGELNFSSDIDLIFAWPEHGCTQGGRWELDNAQFFTRMGQRLIKVLDQPTQDGFVYRVDMRLRPFGESGPLVLSFAALEDYYQEQGRDWERYAMVKARIMGDSEGVYANELRAMLRPFVFRRYIDFSVIQSLRNMKGMIAREVRRRGLTDNIKLGAGGIREIEFIVQVFQLIRGGREPSLQSRSLLPTLSVIAALHLLSENDAEQLRVAYLFLRRLENLLQSINDEQTQTLPSDELNRARLAWAMDFADWPQLTGALTAHMTNVRRVFNELIGDDESETQEESLSEQWRELWQDALQEDDTTPVLAHLSEDDRKQVLTLIADFRKELDKRTIGPRGRQVLDHLMPHLLSDVCAREDAAVTLLRITALLAGIVTRTTYLELLSEFPAALKHLISLCAASPMIASQLARYPLLLDELLDPNTLYQPTATDAYRDELRQYLLRVPEDDEEQQLEALRQFKQAQLLRIAAADIAGTLPVMKVSDHLTWLAEAMIDAVVQQAWVQMVARYGKPNHLNEREGRGFAVVGYGKLGGWELGYSSDLDLIFLHDCPMDAMTDGEREIDGRQFYLRLAQRIMHLFSTRTSSGILYEVDARLRPSGAAGMLVTSTEAFADYQKNEAWTWEHQALVRARVVYGDPQLTAHFDAVRREIMTLPREGKTLQTEVREMREKMRAHLGNKHRDRFDIKADEGGITDIEFITQYLVLRYAHEKPKLTRWSDNVRILELLAQNDIMEEQEAMALTRAYTTLRDELHHLALQELPGHVPEDCFTAERELVRASWQKWLVEE
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia.  When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity.  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity.  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.
Protein: NDHI_GRERE
Sequence: MFPMVTEFMNYGQQTVRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSIIDDYTIRTILNLPEIKT
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: YCIB_LEGPL
Sequence: MKLLFDFFPIVLFFIVYKFFGIYTATAVAMVASLTQVAFYRLKFQHYEKMHLFSLAIIMVLGGATLFFQNPWFIKWKPTGIYWLSALVFYGSGYIGSKPLIQKMMEANINLTTKIWYRLNLAWTLFFIVMGALNLYVAYHYDTDVWVNFKLFGGVGFTLLFVLIQAFYLTKHTDEKSFEKQ
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.