PharMolix/UniProtQA huggingface dataset:
Protein: POLN_DCVEB
Sequence: MESDKSMACLNRILMNKMMFVEDKISTLKMVADYYQKEVKYDFDAVESPREAPVFRCTCRFLGYTIMTQGIGKKNPKQEAARQMLLLLSGDVETNPGPVQSRPVYYRYNDPRYTRLEKAIERRDDKIKTLIKELRRQIKNRKIYSQGMFDKLTKQISDGIKDGVGSEQMNGNLTRICDFLENTLPGLQANIQATVIDTTDKYVSLKEDIMKIVLVILLVRLLMVWKKYRASLCVILIFIFKFYGFDQKLIDLIMDLKNKIFSQGALEDTVEEVVYHPWFHTCGKIIFAVMAFLTIKKIPGKQDWDSYITRLDRIPKSIEGAKKITDYCSEYFNIANDQIKMMVLGKTKEELQRANGLYGEIQAWAQEVRQYLELDQRNKIDLDTETANRVEQLWIKGLKFKSEPLLSKEMSALVHTTLLPAKQLYEYVSCSPVKGGGPRMRPICLWLVGESGVGKTEMVYPLCIDVLREMGMIKKDDFHHQVYGRQVETEFWDGYKGQKIVIYDDAFQKKDDKTAANPEIFEVIRSCNTFPQHLHMAALHDKNTFSAAELLLYTTNDYNVKLESITFPDAFFNRMGDMAYKVSPKKEYGIETEKGNSGKTYLKLDKSKLDKTKAIDLSVYEFQKIVRDEKSDAGWIDSGSPLDYEDFAKLVCSKWKEAKQSSMNKLKFLEEYAIRAQVGSEENSEYGDCIDFVDDIAKRLQKGETLEEIEFDYASDPEMFTQYYHFKSTIKPASRWQKYKDRMDICLSDCKTYLAKKYEEIKKILAEHPILTILGMIGVALSALAMYYWFSKSLDPVEAEVAPSGDAKTVRLPRKLVEIGASGDVKTQKIVKPVVETEWHRNNKGEIEISCDECGMHRMSAFNNMTDEEFDNCTYEDLNKDQKRELAQWSTKDSWLGRFFLSRDRKNKVGIWAEVGQSGDVKTNKAQIKRVEAGAEELVTVALTQGCSDDAAHNLMIDVFQKNTYRMSYFRGDKRYQLGNCTFVRGWSFIMPYHFVQAVFARRLPPNTIISLSQQMSEDLMQIPLSHFFSAGVDNFYLTDNCVRLPFKNGDFRDCVMVNLHSRMCTPHRDLVRHFILTSDQGKLKGSFSGAMATFHVNNMGLYRVYNWLNAVRPCDKKIEIFHPEDGFEYPEESYIQRDCYEYNAPTRTGDCGSIIGLYNKYLERKIIGMHIAGNDAEEHGYACPLTQECLETAFSALVNKNKKNISSQFYYEIPNMVDPLGDSSVPEGKFYALGKSSIRVGQAVNSSIIPSRIYGKLSVPTMKPALLKPTILNNKVHNPLLSGLKKCGVDTAVLSDDEVLSASQDVCRVMLNQYNKNLNKTKYQRILTYEEAIRGTQDDEFMCAINRTTSPGFPYAQMKRNAPGKQQWMGFGEEFDFTSNYALALRKDVEQLIEDCASGKISNVIFVDTLKDERRDIAKVNVGKTRVFSAGPQHFVVAFRQYFLPFAAWLMHNRISNEVAVGTNVYSSDWERIAKRLKTKGSHVIAGDFGNFDGSLVAQILWAIFWEIFVVWLKQFIDIENSEGKRILCICLGLWSHLVHSVHIYEDNVYMWTHSQPSGNPFTVIINCLYNSIIMRLSWIRVMEKFQPRLKSMKWFNEYVALITYGDDNVLNIDAKVVEWFNQINISEVMTEMRHEYTDEAKTGDIVKSRKLEDIFFLKRKFRFSPELQRHVAPLKIEVIYEMLNWSRRSIDPDEILMSNIETAFREVVYHGKEEYDKLRSAVLALKVPQELPENPQILTYNQYLHDIEYLADPLYDF
What is the function of this protein?
RNA-directed RNA polymerase replicates genomic and antigenomic RNA.
What are the official names of this protein?
Replicase polyprotein.
Protein: ISPF_BACP2
Sequence: MLRIGQGFDVHQLTEGRPLIIGGVTIPYEKGLLGHSDADVLLHTVADACLGAIAEGDIGRHFPDTDPEFKDADSFQLLQHVWALVKEKGYTLVNIDCTIMAQKPKMAPYIQPMCEKIAEALEADVTQVNVKATTTEKLGFTGRGEGIASQATVLLQKK
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: RL27_SALPA
Sequence: MAHKKAGGSTRNGRDSEAKRLGVKRFGGEAVLAGSIIVRQRGTKFHAGTNVGCGRDHTLFAKADGKVKFEVKGPKNRKYISIVAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: YBEY_DESHD
Sequence: MYLDINWEEDSIPENERGSLTGLLEQGIAKAVHLSAESEEAEVSLTLVDDARIHELNRDYRGVDRPTDVLSFALQEERSDEPDILDYEDHLLGDIIISVERARAQAIDYGHSFERELVYLAVHGTLHLLGYDHMEEEDKEEMRRQEEAVMSQIGLLR
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BGL34_ORYSJ
Sequence: MGNGGRCMVEVVILLVLMAMSQGCDAQNTTGGLTRKSFPNGFVFGTASSAYQYEGAVKEDGRGPTIWDKFAHTFGKIIDFSNADVAVDQYHRFEEDIQLMADMGMDAYRFSISWSRIFPNGTGEVNQAGIDHYNKLINALLAKGIEPYVTLYHWDLPQALEDKYTGWLDRQIINDYAVYAETCFQAFGDRVKHWITFNEPHTVAVQAYDSGMHAPGRCSVLLHLYCKKGNSGTEPYIVAHNMILSHATVSDIYRKKYKASQNGELGISFDVIWYEPMSNSTADIEAAKRAQEFQLGWFADPFFFGDYPATMRSRVGSRLPKFTEKEAALVNGSLDFMGINHYTTFYTKDDQSTVIEKLLNNTLADTATISVPFRNGQPIGDRANSIWLYIVPRSMRILMNYVKDRYNKPTVYITENGMDDGNSPFISLKNALKDDKRTKYHNDYLTNLADSIREDGCDVRGYFAWSLLDNWEWAAGYTSRFGLYYVDYKNRKRYPKNSVQWFKNLLASSS
What are the official names of this protein?
Beta-glucosidase 34, Os10bglu34.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
Protein: PAP1_SPOEX
Sequence: ENFAGGCTPGYQRTADGRCKATF
What is the function of this protein?
Causes rapid, rigid paralysis when injected into Lepidopteran larvae.  The physiological role may be to reduce hemolymph loss following injury and promote wound healing.
What are the official names of this protein?
Paralytic peptide 1, Paralytic peptide I, PP I.
What is the protein family that this protein belongs to?
Belongs to the GBP/PSP1/paralytic peptide family.
Protein: ATPL_PHOLL
Sequence: MENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPDLIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MATP_ECO55
Sequence: MKYQQLENLESGWKWKYLVKKHREGELITRYIEASAAQEAVDVLLSLENEPVLVNGWIDKHMNPELVNRMKQTIRARRKRHFNAEHQHTRKKSIDLEFIVWQRLAGLAQRRGKTLSETIVQLIEDAENKEKYANKMSSLKQDLQALLGKE
What is the function of this protein?
Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle.  Prevents early segregation of duplicated Ter macrodomains during cell division.  Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.
What are the official names of this protein?
Macrodomain Ter protein.
What is the protein family that this protein belongs to?
Belongs to the MatP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y754_AQUAE
Sequence: MLERLKAITNLLKGALEQRSRAEEGYIREEKVKEAIELLEALERDIMEKELKLAKEALEKFDSNRKFYYLVGKLYVEVSKEEAQKLIEDELKMFGGEGK
What are the official names of this protein?
Uncharacterized protein aq_754.
Protein: SSRP_FRATO
Sequence: MSKHKVSPATIAKNKKALHDYTILEKFEAGIVLQGWEVKSIRAGKVQMVDSHVHIKHGEAWLFNCLITPLLSASTHVVADAAATRKLLLNRREINKIMGRIEQKGFTCIPLSMYWKGPRVKVEIALAQGKKVHDKRQAQKDKDWAREKDRLFKKAYK
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: OVGP1_MESAU
Sequence: MGRLLLWVGLVLLMKPNDGTAYKLVCYFTNWAHSRPVPASILPRDLDPFLCTHLIFAFASMSNNQIVANNLQDEKILYPEFNKLKERNRALKTLLSVGGWNFGTSRFTTMLSTLASREKFIGSVVSFLRTHGFDGLDLFFLYPGLRGSPINDRWNFLFLIEELQFAFEKEALLTQRPRLLLSAAVSGIPYIIQTSYDVHLLGRRLDFINVLSYDLHGSWEKSTGHNSPLFSLPEDPKSSAFAMNYWRNLGAPADKLLMGFPAYGRTFHLLRESKNGLQAASMGPASPGKYTKQAGFLAYYEVCSFIQRAEKHWIDHQYVPYAYKGKEWVGYDDAVSFSYKAMFVKKEHFGGAMVWTLDMDDVRGTFCGNGPFPLVHILNELLVRAEFNSTPLPQFWFTLPVNSSGPGSESLPVTEELTTDTVKILPPGGEAMATEVHRKYEKVTTIPNGGFVTPAGTTSPTTHAVALERNAMAPGAKTTTSLDLLSETMTGMTVTVQTQTAGRETMTTVGNQSVTPGGETMTTVGNQSVTPGGETVTTVGNQSVTPGGETMTTVGNQSVTPGGETVTIVGNKSVTPVGETVTIVGNKSVTPGGQTTATVGSQSVTPPGMDTTLVYLQTMTLSEKGTSSKKAVVLEKVTVPPREISVMPNEQNTALNRENLIAEVESYSQDG
What is the function of this protein?
Binds to oocyte zona pellucida in vivo.  May play a role in the fertilization process and/or early embryonic development.  Might act as a protective secretion influencing the first steps of the reproductive process necessary for the normal triggering of fertilization and early embryonic development.
What are the official names of this protein?
Oviduct-specific glycoprotein, Estrogen-dependent oviduct protein, Oviductal glycoprotein, Oviductin, ZP-0.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle. Note=Secretory granules.
Protein: SP2G_CLOAB
Sequence: MVIYLDVLIFENSIVNTFLLYITAQTLRIKVKMRYLILAGIFGGLYVIVLVIPTLKIFSSLIFKIIAAFLMIIICFRKKSLRFNIKALAVLIMYSMVTAGLCFFIELNNTRGSYFNAFIGNVSYKWILIAIMIIYMFVNRIIWFINDRKLTQSLIYEIEICFKDNSKFINAFLDTGNELREPITNLPVIVVEKDMVSGIKWDDCPKFYVPFRLFNGKAGNLEAFKPSYVKIYIGDKVEVRNAIIALIDNKLSSLNDYNALLSRGSI
What is the function of this protein?
Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation.  Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR (By similarity).
What are the official names of this protein?
Probable sporulation sigma-E factor-processing peptidase, Membrane-associated aspartic protease, Stage II sporulation protein GA.
What is the protein family that this protein belongs to?
Belongs to the peptidase U4 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HRCA_SINFN
Sequence: MVLRNPEKKGIASTLDERSGEIFRRIVETYLESGEPLGSRNLSRLLPMSLSPASVRNVMSDLEDLGLIYSPHVSAGRLPTQTGLRFFVDAFMQVGNLSAEERTSIERQVRRADRDQPIDSLLAEASQMLSGMSRGAGLVITTKSDPVLKHVEFIRLAPTKALAVLVGDHDQVENRIIELPAGITSAQLTEAANFVNAHLAGQTIPELRSQLEKVKETVRGELDALSQDLVERGLAIWSGSEGDEKPARLIVRGRANLLEGLEGTEDIERLRMLFDDLEKKDSLIELLDLAESGPGVRIFIGSENKLFSLSGSSLIVAPYRDSDDRIVGAVGVIGPTRLNYSRIVPMVDYTAQLMSRLSR
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: PP12C_HUMAN
Sequence: MSGEDGPAAGPGAAAAAARERRREQLRQWGARAGAEPGPGERRARTVRFERAAEFLAACAGGDLDEARLMLRAADPGPGAELDPAAPPPARAVLDSTNADGISALHQACIDENLEVVRFLVEQGATVNQADNEGWTPLHVAASCGYLDIARYLLSHGANIAAVNSDGDLPLDLAESDAMEGLLKAEIARRGVDVEAAKRAEEELLLHDTRCWLNGGAMPEARHPRTGASALHVAAAKGYIEVMRLLLQAGYDPELRDGDGWTPLHAAAHWGVEDACRLLAEHGGGMDSLTHAGQRPCDLADEEVLSLLEELARKQEDLRNQKEASQSRGQEPQAPSSSKHRRSSVCRLSSREKISLQDLSKERRPGGAGGPPIQDEDEGEEGPTEPPPAEPRTLNGVSSPPHPSPKSPVQLEEAPFSRRFGLLKTGSSGALGPPERRTAEGAPGAGLQRSASSSWLEGTSTQAKELRLARITPTPSPKLPEPSVLSEVTKPPPCLENSSPPSRIPEPESPAKPNVPTASTAPPADSRDRRRSYQMPVRDEESESQRKARSRLMRQSRRSTQGVTLTDLKEAEKAAGKAPESEKPAQSLDPSRRPRVPGVENSDSPAQRAEAPDGQGPGPQAAREHRKVGKEWRGPAEGEEAEPADRSQESSTLEGGPSARRQRWQRDLNPEPEPESEEPDGGFRTLYAELRRENERLREALTETTLRLAQLKVELERATQRQERFAERPALLELERFERRALERKAAELEEELKALSDLRADNQRLKDENAALIRVISKLSK
What is the function of this protein?
Regulates myosin phosphatase activity.
What are the official names of this protein?
Protein phosphatase 1 regulatory subunit 12C, Protein phosphatase 1 myosin-binding subunit of 85 kDa, Protein phosphatase 1 myosin-binding subunit p85.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, stress fiber.
Protein: KDPC_RHIME
Sequence: MLNQLRPALVLTFALTLITGLGYPLLITGVAQALMPAEANGSLVRKGSVLIGSQLIGQNFASEKYFWPRPSATGPEPYNAVASSGSNLGTTSDKLKERVAADIERLRAAGIGGEIPADAGMASGSGLDPHISPEFARVQIARVAKARGLPEAGVDALVDRATQGRLFGLIGEPRVNVLELNLALDAPRT
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: HTPG_STRCO
Sequence: MTTETFEFQVEARQLLQLMIHSVYSNKDVFLRELVSNASDALDKLRLAALRDDAPDADVSDLHIELEVDKDARTLTVRDNGIGMSYDEVTRLIGTIANSGTAKFLEELREAKDAAGADGLIGQFGVGFYSGFMVADEVTLVTRHAGETEGTRWTSRGEGTYTLERIGEAPQGTAVTLHLKPADVENQLHDYTSAWKIKEIVKRYSDFITWPVRLLPEPGGDGSDGEGAEAREAETLNSMKALWARPRDEVSDDEYHELYKHIAHDWRDPLETIRLQAEGTFEYQALLFVPSHAPHDLFTQGYQRGVQLYVKRVFIMDDCEELLPPHLRFVKGVVDAQDLSLNVSREILQQDRHIRMIQRRLTKKVLSTVKDLRTSAPDRYATFWREFGAVLKEGLVTDSDNRDAILAACSFASTHDAEEPTALKDYVERMKEGQDDIYYMTGESRQAIENSPHMEAFRAKGVEVLLLTDAVDEVWVDAVGEYEGKTLRSVAKGEIDLSGTEADKSDAEKEKQGEEYAGLLGWMTEHLGEEVKEVRLSSRLTVSPACVVSDAGELTPALENMYRAMGQEVPGAKRILELNPEHQLVKSLNRAWTDRQDRAELTETAELLHALAVLAEGGRPKEPARFVQLMADRLERTL
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABZ_PHOLL
Sequence: MSDNHTLHIEEILDLLPHRYPFLLVDRVLDFEEGKFLRAVKNVSFNEPFFQGHFPGKPIFPGVLILEAMAQATGILAFRSVGKLEPNELYYFAAIDGARFKRPVVPGDQMILEVEFIKERRGVARCRGVAKVDGEIACEAEMMCARRREV
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YL091_MIMIV
Sequence: MDLGEIEKDFTKIDEYFFDACNIKSYNYNGTYYCCKNISSTHFTKLMYLIINEKNSTNGHQKIIKYLKKKINVKNPSRINRQNDEGWTALMIASITCGQWCSIETVRLLLEHGANPNIQEKNGLQLSGIKSQLAHIISLICKTMRQKNSNPENGFTALSLACAVLDTGESVEVVELLLKYGTNVDSINHNGETALIITCQNSKYFHSIFVIDLLLQNNANTLHKDNNGFTALIHAVSHCPLNIVKLLVKNGSDVNATDNEGKSVLMHSTKNSIDIVKYLLKKGAEINHKNNNDINVLFFASKNHVKSDVIMFLLAKCSNPNEINTNKNAVLAHVCRQFNHHKNDIDTVKILLENRANPNIIDDDSRTILMDICTDYQNENSLDIIEMLLKKGANVNATDIEGRTALNYACMSINNKITIKIIKLLLKYNINVNHVDNDGAHILIDLCRNYSRYSLKVVKLLLEHGADVNITFGNKKWTPLFFANENLFSSSEKDPERCTKLIDLLIHYGANVNAVGKYGNNILMEDTTRNLECPNSITKHLLEKKINVNHQNDNGDTSLLLVYERHELERAYSIAQFLLEHGCNPNIINKNEHNILTILNNDIFWNFEKVIPHFKLFLNYNFNPNIYQIYGCHFILINVLLI
What are the official names of this protein?
Putative ankyrin repeat protein L91.
Protein: PA_I80A2
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDFHFVDERGESIIVESGDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGIEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSERGEETIEERFEITGTMRRLANQSLPPNFSSLENFRAYVDGFEPNGCIEGKLSQMSKEVNARIEPFLKTTPRPLRLPEGPPCSQRSKFLLMDALKLSIEDPSHEGEGIPLYDAIKCMKTFFGWKEPNIVKPHEKGINPNYLLAWKQVLAELQDIENEEKIPKTKNMKKTSQLKWALGENMAPEKVDFEDCKDVSDLKQYDSDEPEQRSLASWIQSEFNKACELTDSSWIELDEIGEDVAPIEHIASMRRNYFTAEVSRCRATEYIMKGVYINTALLNASSAAMDDFQLIPMISKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKWEKYCVLEIGDMLLRTAIGQVSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAESSVKEKDMTKEFFENNSETWPIGESPKGVEEGSIGKVCRTLLAKSVFNSLYASPQLEGFSAESRKLLLIVQALRDNLEPGTFDLGGLYEAIEECLINDPWVLLNASWFNSFLTHALK
What is the function of this protein?
Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits.  The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching.  It consists in the hijacking and cleavage of host capped pre-mRNAs.  These short capped RNAs are then used as primers for viral mRNAs.  The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
What are the official names of this protein?
Polymerase acidic protein, RNA-directed RNA polymerase subunit P2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=PB1 and PA are transported in the host nucleus as a complex.
Protein: SYH_FLAJ1
Sequence: MASKPSIPKGTRDFSPAEVSKRQYIIQTIKANFEKFGFQPIETPSFENSDTLMGKYGEEGDRLIFKILNSGNFFYNKSKIELPESIEELQLNSAEKITLEQRIELNKFTGKISEKALRYDLTVPFARYVVQHQSEIEFPFKRYQIQPVWRADNPQKGRFREFFQCDADVVGSKSLWQEVELVQLYDTVFTSLGLEGVTIKINNRKILSGIAEVIGASDKLIDFTVALDKLDKIGEDGVKKEMIEKGISEDALVKVQPLFNFSGTFADKIAQLSDLLSSSEEGMKGVEELKFICDNVADLGLSTAVLDLDVTLARGLNYYTGAIFEVAAPKTVAMGSIGGGGRYDDLTGIFGLKNMSGVGISFGLDRIYLVLEELQLFPETVAATSKAIFLNFGDKEALYASKAIQKLRQENIKVELYPDNVKVGKQFQYADKRLIPFAVLVGDQEINSNSYALKNLVTGEQVSVDFEGLKKTLLG
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPH_ECO55
Sequence: MNFLAHLHLAHLAESSLSGNLLADFVRGNPEESFPPDVVAGIHMHRRIDVLTDNLPEVREAREWFRSETRRVAPITLDVMWDHFLSRHWSQLSPDFPLQEFVCYAREQVMTILPDSPPRFINLNNYLWSEQWLVRYRDMDFIQNVLNGMASRRPRLDALRDSWYDLDAHYDALETRFWQFYPRMMAQASHKAL
What is the function of this protein?
Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP.
What are the official names of this protein?
Acyl carrier protein phosphodiesterase, ACP phosphodiesterase.
What is the protein family that this protein belongs to?
Belongs to the AcpH family.
Protein: PYRB_MYCGI
Sequence: MKHLLTAADLSRDDATAILDNADRFREALVGREVKKLPTLRGRTIITMFYENSTRTRVSFEVAGKWMSADVINVSASGSSVAKGESLRDTALTLRAAGADALIIRHPASGAPQQLAAWTLDEHGGPSVINAGDGTHEHPTQALLDALTIRQRLGSVEGKRVVIVGDVLHSRVARSNVALLHTLGAEVVLVAPPTLLPVGVTEWPVTVSHELDAELPLADAVLMLRVQAERMNGGFFPSSREYSVRYGLSEKRQSTLADHAVVLHPGPMLRGMEIAYSVADSSQSAVLQQVSNGVHVRMAVLFHLLVGSEEEAISA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: METAS_THIND
Sequence: MPLVAHSNLPTFERLRKEGGTVLPNDYALHQDIRALHIGLLNMMPDAALAATERQFFRLVGESNQIAQFYMHPFTLAELPRGPGGQAHVERYYETFDTIQREGLDALIITGANVSQPDLALEPFWEPLAEVVEWAWKNVTSTLCSCLTTHAVMQSRYGERRRHRGAKLWGVFDHRVVDRTHPLVAGVNTRFDVPHSRFNDVSREQFDRHRLKVLVESERAGVHLAVSEDGFRLVFFQGHPEYDSISLLKEYKREVLRFVNGEREEFPPLPERYLSPQAAAILEEHRERVEQARQRRVPAPELPEPLLVGRLDNTWHDSALAVVNNWIGNVYQFTNHDRRIPFRPGVDPNAPLNWSR
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHK_SCHPO
Sequence: MATQNDIPNSTPEDLAKQVEIAEKHPDPPAMPSRLPDSLKTLEAKIDTSKITDEEVANVHRFQRACDYLAASLIFLSNGLYTGGDLEEKDIKTRLLGHWGTCPGLSIVYSHCNRIINKYDLNMLFVVGPGHGAPAILSALFLEDSLGPFYPRYQFTKEGLNNLINTFSLPGGFPSHVNAEVPGAIHEGGELGYALSVSYGAVLDRPDLIVTCVVGDGEAETGPTATSWHAHKFLDPAESGAVIPVLELNGYKISERTIYGCMDDSELLSLFSGFGYEVAIVNDTPDQNRVMAATMDWAVERIHDIQHRARVNREEIKPRWPMIILRTPKGKGCPKYLNGKFLEGTFRAHQVPLKLARTDTNQRNLLKDWLNSYNCQDFLDEHGLPTKGITEHLPPREKRMGQRHETYNSYLPLKVPDWKKYGVKKGETTSATSVVGQYLDELLVTNDSTLRIFSPDELESNKLDGALKHSYRTMQTDPELMAKRGRVTEVLSEHLCQGFMQGYTLTGRTAIFPSYEAFMTIVVSMLVQYSKFLKMGLETGWHGKFGSLNYVTSSTWARQEHNGFSHQSPRFITTMLSLKPGVSRVYFPPDANCFLATVARCMKSENTINLMVSSKNPQPAYLSVEEAEHHCKAGASVWKFASTDNGENPDVVIAGVGNEIMFEVVKAAEMLQNDIPELRVRVINVTDLMVLSSLHPHGMNPAEFDSLFTKDRHVHFNYHGYVMDLKALLFDRIQGTRVTMEGYREEGTTTTPFNMMMCNNTSRYHVARMALQHALHNPTVAVNCNMLCAKYAWKLEEIENYIMENKDDPPEIYAAPVFKNKTSTL
What are the official names of this protein?
Probable phosphoketolase.
What is the protein family that this protein belongs to?
Belongs to the XFP family.
Protein: PNP_ECODH
Sequence: MLNPIVRKFQYGQHTVTLETGMMARQATAAVMVSMDDTAVFVTVVGQKKAKPGQDFFPLTVNYQERTYAAGRIPGSFFRREGRPSEGETLIARLIDRPIRPLFPEGFVNEVQVIATVVSVNPQVNPDIVAMIGASAALSLSGIPFNGPIGAARVGYINDQYVLNPTQDELKESKLDLVVAGTEAAVLMVESEAQLLSEDQMLGAVVFGHEQQQVVIQNINELVKEAGKPRWDWQPEPVNEALNARVAALAEARLSDAYRITDKQERYAQVDVIKSETIATLLAEDETLDENELGEILHAIEKNVVRSRVLAGEPRIDGREKDMIRGLDVRTGVLPRTHGSALFTRGETQALVTATLGTARDAQVLDELMGERTDTFLFHYNFPPYSVGETGMVGSPKRREIGHGRLAKRGVLAVMPDMDKFPYTVRVVSEITESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEGDNYVVLSDILGDEDHLGDMDFKVAGSRDGISALQMDIKIEGITKEIMQVALNQAKGARLHILGVMEQAINAPRGDISEFAPRIHTIKINPDKIKDVIGKGGSVIRALTEETGTTIEIEDDGTVKIAATDGEKAKHAIRRIEEITAEIEVGRVYTGKVTRIVDFGAFVAIGGGKEGLVHISQIADKRVEKVTDYLQMGQEVPVKVLEVDRQGRIRLSIKEATEQSQPAAAPEAPAAEQGE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPC_STRP7
Sequence: MSQEFLARILEQKAHEVEQMKLEQIQPLRQTYRLAEFLKNHQDRLQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGTVMISVLTDEVFFKGHLNYLREISSQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKKLYDYATELGLEVLVETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTGQDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: ORML3_RAT
Sequence: MNVGTAHSEVNPNTRVMNSRGIWLSYVLAIGLLHVVLLSIPFVSVPVVWTLTNLIHNLGMYIFLHTVKGTPFETPDQGKARLLTHWEQMDYGVQFTASRKFLTITPIVLYFLTSFYTKYDQVHFILNTVSLMSVLIPKLPQLHGVRIFGINKY
What is the function of this protein?
Negative regulator of sphingolipid synthesis.  May indirectly regulate endoplasmic reticulum-mediated Ca(+2) signaling (By similarity).
What are the official names of this protein?
ORM1-like protein 3, Liver regeneration-related protein LRRGT00183.
What is the protein family that this protein belongs to?
Belongs to the ORM family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.