PharMolix/UniProtQA huggingface dataset:
Protein: VF169_ASFWA
Sequence: MNVDFIAGINNLGEKIYTCEPFKTSFQNPFIVALIITAVVLVIFFAICNPPVDKKRKTKTAIYVYICIVALLFLHYYVLNHQLNEIYNKSNMDVIVSSIHDKYKGGDEIIPPISPPSVSNELEEDQPKKIPAGPKPADSKPAADSKSLVPLQEVIMPSQYNN
What are the official names of this protein?
Transmembrane protein B169L, pB169L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus B169L family.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein. Virion.
Protein: ERA_ENT38
Sequence: MSEEKSYCGFIAIVGRPNVGKSTLLNTLLGQKISITSRKAQTTRHRIVGIHTEGEYQAIYVDTPGLHMEEKRAINRLMNKAASSSIGDVELIIFVVEGTRWTADDEMVLNKLRDGRAPVILAVNKVDNVQEKADLLPHLQFLASQMNFLDIVPLSAESGMNVDTIAGIVRKHLPEAIHHFPEDYITDRSQRFMASEIIREKLMRFLGAELPYSVTVEIERFQTNERGGYDINGLILVEREGQKKMVIGNKGSKIKTIGIEARKDMQDMFEAPVHLELWVKVKSGWADDERALRSLGYGDDV
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: ILVC_SULAC
Sequence: MAKIYTDKDVSLDVIKEKRVAVLGYGSQGRAWALNLRDSGIKVSVGLEREGNSWKQAENDGFKPLRTEEAVRNSDIIIFLLPDMIQRTVYLERVKPYLKEGMDLVFAHGFNIHYRLIEPPSNVDVYMIAPKAPGPIVREYFAKGGGVPALVATYQDHSGKALQKALAVAKAIGATRAGVIETTFKEETETDLFGEQVDLVGGVMQLMRYAFQTLVEAGYQPEVAYFETINEMKLIVDLVYEKGFSGMLTAVSDTAKYGGMTVGKMVIDESVKERMKKALDNIRSGKFAEKWVEEYGKGANTIKEGMKEVDNSTEEKVGRSLRDIILRGKPKS
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: TYB4_NOTEU
Sequence: MSDKPDMGEIQKFNKSKLKKTETQEKNPLPSKETIEQEKQAGES
What is the function of this protein?
Potent inhibitor of bone marrow derived stem cell differentiation (By similarity).  Acts by inhibits the entry of hematopoietic pluripotent stem cells into the S-phase (By similarity).
What are the official names of this protein?
Thymosin beta-4, T beta-4.
What is the protein family that this protein belongs to?
Belongs to the thymosin beta family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: GATA_RHILO
Sequence: MSDLTRLTISQARAKLRGKEITATEITEAYLSAIDRANPALNAYVAVTGDRARDMAKASDARLVKGEGGALEGIPLGIKDLFGTEGVHTQACSHVLDGFKPLYESTVTANLWADGAVMLGKLNMDEFAMGSSNETSYYGPVINPWRRSRLDTVVMPTTHQGDGGFVSAGGTKTQRSLDNAQLVPGGSSGGSATAVSAFLCAGATATDTGGSIRQPAAFTGTVGIKPTYGRCSRWGIVAFASSLDQAGPIARDVRDAAILLKSMASVDPKDTTSVDRPVPDYEAAIGKPIKGMKVGIPKEYRVDGMPEEIEALWQKGIAWLRDAGAEIVDISLPHTKYALPAYYIVAPAEASSNLARYDGVRYGLRVPGKDIVEMYEKTRAAGFGREVKRRIMIGTYVLSAGYYDAYYLQAQKVRNLIKRDFENVFAAGVDVILTPATPSAAFGIADEDMAADPVKMYLNDIFTVTVNMAGLPGIAVPAGLDPKGLPLGLQLIGRPFEEETLFQTAAVIEQAAGTFQPEKWW
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: CRCB_CYTH3
Sequence: MLHFILVLVGGAIGSGSRYLLSLHITRTYPGTFPYSTFAVNIIGCLLIGIIYGLAERFQLAVHWRLFLATGLCGGFTTFSAFAYENILLLQNGNYTAFTVNTLGSCMFGFTAVFLGVMLTKISI
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: COROB_DICDI
Sequence: MFKVSKYRHTVGKIDKRELWYPDVNTTGNSSASTFIKANSKWVALNWQSNTGTIGLIPLKSFGKRKGETFLIHAHSSGVIDFEFNPFNEHQLVTASDDSTIKVWNIDEAIRSGATSLSSASIVCSGHSKSVECIAFNPVANNILASCSADKTLKIWDLSNGEEKYSWNFEQGSLTSLSWNYDGSLLVATGKDLKNRIIDARTGESIQVGDGNQGVKASRVVWLGNLNHFLTAGFSKMRERQLVLWSSQDLSKPIKSITLDSSTGIISPIYDQDAQLLFISGSGDSSVRVFDMNTQFTKDPAFTELSPVPSDTPSKGICALPKRALDVMEVEIDRIFKATPNNIIPITFNMSRKSKSTFADDLFPNTASTKPSLSSIDWLSGENKQPILVSLNPSDNQINNDLDDLQLNDNEPVKKSTFFIDDNTNDNSNVVEQSKSEPEQQQQEEKKISSSSSSSSPTNSSSNVINSTPSSPIVNDNIQRTGIVPKVVRSSKYRHISGSAHQKSQFYTNLKINGSTSNTCIAVNSEYVAVPMVGIGGPLAVIPLADKGRQIQVPCIEIGSQLCDYDLSQHNTSLVATGSEDSHVKVFKIPTGGIPKTTANKSNNYTTTEADFVGHNRKVISVNFHPTAENVLITSGGDMVVKLWDLNEGGAGEKLSFANVHTDMITSVDVNWTGDKILTSSKDKKMRIFDPRTNKGGLASETVTHSGSKGGKAVWLGQTGNIFSVGFNKSSEREYQLWDSRNLQSGTPLASDKLDHLSGVITPFYDEDSGVIYLAGKGDSSIRMFEINDQEPYVHYLTQFSAGTPQVGVAKFAKKTSMDVKKCEIARFYRSTDSTIEPLSMTVPRNRQEFFQDDIYPDTRQTCTPVMTSEEWFDGCIREPEFVSMKPSDMINLSDAPPPPKKEDKFVVSQEVDNTPSRDQVTNSLLSRVSNQNASSNWEQIEKLKHNFTDYDNGDISDSEWD
What is the function of this protein?
Involved in phagocytosis and cell motility.  Binds to actin filaments and protects them against depolymerization.
What are the official names of this protein?
Coronin-B, Coronin-7, DdCRN7, Doublecoronin.
What is the protein family that this protein belongs to?
Belongs to the WD repeat coronin family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection. Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Note=Accumulates in cell surface projections during movement, phagocytosis and pinocytosis. Detected at the leading edge of the cell during chemotaxis.
Protein: GLYA_FRAP2
Sequence: MFSFEKNSLKNTDKEIFDAIELEVKRQHEHVELIASENYASPAVMEAQGSQLTNKYAEGYHGKRYYGGCEFVDIAEKLAIERAQKLFGVDYANVQPHSGSQANAAVYNAVLKPGDTVLGMDLGAGGHLTHGSKVNFSGKIYNSIQYGLSESGDIDYKQVAELAKEHKPKMIIAGFSAFSGIIDWKKFREIADSVDAVLMADIAHVAGLVAAGLYPNPFPYVDVATTTTHKTLRGPRGGLILCNDNPDLAKKFQSAIFPGIQGGPLMHVIAAKAVAFKEALEPSFIDYQKQVLINAKAMEKVLKERNINIISGGTNNHLLLLDITNTGFSGKEAEAALGRANITVNKNSIPNDPRSPFVTSGLRIGSPAITTRGFKEAECEQIANWLADVVYNCGNEKVENETATKVSELCDRFPVYK
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y5558_CUPPJ
Sequence: MSVERQWYLYLLECTGGSIYTGITTDVARRFAQHQAGKGAKYTRSRKPLRVLGQVAFPSKSEALKAELATKRMSSAQKIAFCAKLEQPET
What are the official names of this protein?
UPF0213 protein Reut_B5558.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: MTAL2_PICAN
Sequence: MDDMLTKIQERTKCLIYILMERQIRAARLEQLLLDYISCKPHDKLCKSSMEGFTTERSLKYTRDCPQYAAVTTSQPRYRIEKRSKRFPKTAQMELENWYTENEDNPYLSKRDLQQLVHKTGLCAPQVRNWVSNRRRKERTLTISKELSDLLNQDTRCSPNDVV
What is the function of this protein?
Mating type proteins are sequence specific DNA-binding proteins that act as master switches in yeast differentiation by controlling gene expression in a cell type-specific fashion.
What are the official names of this protein?
Mating-type protein ALPHA2, MATalpha2 transcription factor.
What is the protein family that this protein belongs to?
Belongs to the TALE/M-ATYP homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL25_SHISS
Sequence: MFTINAEVRKEQGKGASRRLRAANKFPAIIYGGKEAPLAIELDHDKVMNMQAKAEFYSEVLTIVVDGKEIKVKAQDVQRHPYKPKLQHIDFVRA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: RS5_LACH4
Sequence: MANRNDSRNNRRNKDDIEDQLVAVNRITKVVKGGRRMRFAALVVVGDKKGRVGFGTGKAQEVPEAIRKAVEDGKKKMINVPKVGTTIPHEVIGHYGSGNILLKPAEAGSGVAAGGAVRIVMDMAGISDVTSKSLGSNTPINVVRATIDGLKKLRTSEEVNKLRQPERA
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: MED30_DICDI
Sequence: MDKIEIEEELICSLAVKGEKSIHKLLLNILAIVKQLKTIQSDPVLTYQVSTKAQQQLQSQQLQQPQSIPSSTNNSTNTNTNNSTTTTTTSSTSSTTTPTTTTSTTSPLNSKDSTATTTTKEQPSSPTLPTLNLNFVNDNDKIKELNQNCIQSILALQKTIKEISLLETKISQKPKDNIDNDDTIMKDDNNNSSTSAPTTTTINIEKQDQTSLSNELERLKMDAYQKNCVIKKLIDNMRLLQLSINSMNRTSTGTD
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Putative mediator of RNA polymerase II transcription subunit 30, Mediator complex subunit 30.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 30 family. Highly divergent.
What are the subcellular locations of this protein?
Nucleus.
Protein: COAX_DESHY
Sequence: MILVFDVGNTNIVLGVYEQKDLIYHWRISTDKSRTVDEYAVIIKNLFDLNGLDMSRIKAVVMSSVVPPVMPTLESLARKYFDVEPLVIGPGVKTGMPIVYDNPREVGADRIVNAVAAYHKYGGPLVIVDFGTATTFCAISKRGEYLGGAIAPGVGISTEALFQRASKLPRIEIVKPKSIIAKNTVAGMQSGIYYGYTGQVDRIVTLMKQELGRDTRVIATGGLAELIQEDSQEIETVDPFLTLEGLLLIYERNSNQQP
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPFF_MOUSE
Sequence: MDSKWAALLLLLLLLLNWGHTEEAGSWGEDQVFAGEDKGPHPPQYAHIPDRIQTPGSLFRVLLQAMDTPRRSPAFLFQPQRFGRSAWGSWSKEQLNPQARQFWSLAAPQRFGKK
What is the function of this protein?
Morphine modulating peptides.  Have wide-ranging physiologic effects, including the modulation of morphine-induced analgesia, elevation of arterial blood pressure, and increased somatostatin secretion from the pancreas.  Neuropeptide FF potentiates and sensitizes ASIC1 and ASIC3 channels.
What are the official names of this protein?
Pro-FMRFamide-related neuropeptide FF, FMRFamide-related peptides.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: DGTP_ECO7I
Sequence: MAQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDELTGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLHPEDAESQPLTDDRCSVAALRLRDGEEPLNELRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVADLEDAVEKRIFTVEQLYHHLHEAWGQHEKGSLFSLVVENAWEKSRSNSLSRSTEDQFFMYLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFSHPDVEQLELQGYRVISGLLEIYRPLLSLSLSDFTELVEKERVKRFPIESRLFHKLSTRHRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVEQ
What is the function of this protein?
dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs.
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase, dGTP triphosphohydrolase, dGTPase.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 1 subfamily.
Protein: DAPE_BURM7
Sequence: MSATLALTEQLIARASVTPDDQHCQQLMIERLAALGFECETIASHGVTNFWAVKRGTAGRAGKLLAFAGHTDVVPTGPLEQWRSPPFVPTHRDGKLYGRGAADMKTSLAGFVVAAEEFVAAHPQHRGSIGFLITSDEEGPATDGTVKVVEALAARGERLDYCIVGEPTSTATLGDVVKNGRRGSMSGELVVKGVQGHIAYPHLAKNPIHLLAPALAELAAEQWDEGNEYFPPTTWQVSNLRAGTGATNVIPGHADLLFNFRFSTASTVEGLQARVHAILDRHGLDYTLNWSVSGLPFLTPRGELSNALDAAIRAETGVSPELSTTGGTSDGRFIARICPQVIEFGPPNASIHKIDEHIDVRFVDPLKNVYRRVLEQLIA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: LYS2_CANGA
Sequence: MSWKERLDNPTLSVWPHDYLRPHAEPFVEQGTYSISIPQLSGDYATLLAAWTALLYRVTGDDDIVLYVRDNKVLRFTITPELTFTQLQNKINEQLAELANVEGTNFDALSESLQKESGLERPPQLFRIACVTEDLQLDRYTHSPLDIGLQLHESSSDVSIVFNKLLFSQDRITILADQLTLFLTSVLQNAKQVFTKVSLITDSSTSILPDPKANLDWCGFVGCIHDIFQDNAEKFPERTCVVETPPINSTKTRTFTYKDINEASNIVAHYLINTGIKRGDVVMIYSSRGVDLMVCVMGVLKAGATFSVIDPAYPPARQTIYLGVAKPKGLIVIRAAGQLDQLVEDYITKELDLVSRIPSIAIQDNGTVEGGSLPSESGDVLASYTELKSTRTGVVVGPDSNPTLSFTSGSEGIPKGVLGRHFSLAYYFSWMAKQFNLSENDKFTMLSGIAHDPIQRDMFTPLFLGAQLYVPTQDDIGTPGRLAEWMGKYGCTVTHLTPAMGQLLTAQAVTPFPKLHHAFFVGDILTKRDCLRLQTLAENCCIVNMYGTTETQRAVSYFEVTSRSQDPHFLKKLKDVMPAGRGMKNVQLLVVNRNDRTQVCGVGEIGEIYVRAGGLAEGYRGLPDLNKEKFVNNWFVEEGHWNYLDKDLEAPWKEFWQGPRDRLYRTGDLGRYLPNGDCECCGRADDQVKIRGFRIELGEIDTNISQHPLVRENITLVRNNLEGEKCLVTYMVPRFDKPELENFKIEVPSNISDDPVVCGLIGYSPFTKDLKAFLKKRLASYAIPSLIIVLPKLPLNPNGKVDKPKLQFPTVKQLELVAKNSSIDINDSEFNQQEREIRDLWLECLPTKPTSISPEDSFFDLGGHSILATKMIFTVKKQLNVELPLGTIFKYPTIKAFAAEVSRLKSTDKIEEETTALTADYASDAASLIDTLPKSYPAARALGSPSEMAGPTTVNIFVTGVTGFLGSFILSDILNRTVTGVNFKIFAHVRAADETSGLDRIRKAGTVYGTWKEEYANSLQVVIGDLSKKNFGLTDDKWSHLSETIDIIIHNGALVHWVYPYSKLRNANVVSTINIMNLASEGKPKLFNFVSSTSVLDTNHYFELSDKLQQSGKEGIPESDDLMGSSLGLTSGYGQSKWAAEHIIRAAGKRGLRGSIIRPGYVTGASYNGSSNTDDFLLRFLKSAVQLGKIPDINNTVNMVPVDQVARVVVAASINPPCGDDLCVVHVNAHPRIIFKDYLYELKNYGYDVEIENYEQWKKTLEEAVIERSEDNALFPLLHMVLGDLEDSTKAPELDDKNAITSLRADIEWTNEDRTKGMGATPEQIGIYISFLESVGFLPHPKHFGDKALPNIKISEQQKELVASGAGARSSSAA
What is the function of this protein?
Catalyzes the activation of alpha-aminoadipate by ATP-dependent adenylation and the reduction of activated alpha-aminoadipate by NADPH.  The activated alpha-aminoadipate is bound to the phosphopantheinyl group of the enzyme itself before it is reduced to (S)-2-amino-6-oxohexanoate.
What are the official names of this protein?
L-2-aminoadipate reductase large subunit, Alpha-aminoadipate reductase, Alpha-AR, L-aminoadipate-semialdehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: GL1D1_MOUSE
Sequence: MRLLFLAVLRPHTGNAVTAGRLRDHLEAAGHMCVLRDAFDFESPSEIANLIMDENLEAALALHLYRGGRLLQGHSIPFGVIFGGTDLNEDANHKEKKEVMGKVLEEARFAVAFTEAMKDTAQVQWPHATGKIFVQSQGIATIPNANFNWNTFLQQSEIDQSADNLYIFLIICGLRPVKDPLYLVDAFSEWHQETPNVYMVIVGPEVDPVFTREVKERVRRAAGVRLIREMCQEDLHAVVKSCFALVNSSVSEGMSAAILEAMDLEVPVLARNIPGNSAVVEHGVTGLLFSNPQEFIQLAKRLVSDPALEKEIVTNGREYVRTHHSWQVERDTYQRLIRKLETNLED
What are the official names of this protein?
Glycosyltransferase 1 domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: METJ_VIBCH
Sequence: MADWNGEYISPYAEHGKKSELVKKITVSIPLKVLKVLTDERTRRQVNNLRHATNSELLCEAFLHAYTGQPLPTDEDLRKDRPDDIPAEAKRLMTEMGIEFESYDE
What is the function of this protein?
This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.
What are the official names of this protein?
Met repressor, Met regulon regulatory protein MetJ.
What is the protein family that this protein belongs to?
Belongs to the MetJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTPPA_RHIEC
Sequence: MALKYKLILASGSPRRVDLLNQAGIEPSRLMPMDIDETPKKSEHPRSLARRLSAEKAEAALAAIKGDITWKGSYILSADTVVAVGRRILGKAEFADEALSSLHLLSGRNHLVYTGICLVTPDRKIRQKIVETKVRFKRLSGFEIENYLASGQWRGKAGAYGIQGLAGTFVQKMVGSYTNVVGLPLYETILLLTGEGFDVHSRWPEG
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPSD_TTVG1
Sequence: MPFWWGRRNKFWYGRNYRRKKRRFPKRRKRRFYRRTKYRRPARRRRRRRRKVRRKKKTLIVRQWQPDSIVLCKIKGYDSIIWGAEGTQFQCSTHEMYEYTRQKYPGGGGFGVQLYSLEYLYDQWKLRNNIWTKTNQLKDLCRYLKCVMTFYRHQHIDFVIVYERQPPFEIDKLTYMKYHPYMLLQRKHKIILPSQTTNPRGKLKKKKTIKPPKQMLSKWFFQQQFAKYDLLLIAAAACSLRYPRIGCCNENRMITLYCLNTKFYQDTEWGTTKQAPHYFKPYATINKSMIFVSNYGGKKTEYNIGQWIETDIPGEGNLARYYRSISKEGGYFSPKILQAYQTKVKSVDYKPLPIVLGRYNPAIDDGKGNKIYLQTIMNGHWGLPQKTPDYIIEEVPLWLGFWGYYNYLKQTRTEAIFPLHMFVVQSKYIQTQQTETPNNFWAFIDNSFIQGKNPWDSVITYSEQKLWFPTVAWQLKTINAICESGPYVPKLDNQTYSTWELATHYSFHFKWGGPQISDQPVEDPGNKNKYDVPDTIKEALQIVNPAKNIAATMFHDWDYRRGCITSTAIKRMQQNLPTDSSLESDSDSEPAPKKKRLLPVLHDPQKKTEKINQCLLSLCEESTCQEQETEENILKLIQQQQQQQQKLKHNLLVLIKDLKVKQRLLQLQTGVLE
What is the function of this protein?
Self-assembles to form an icosahedral capsid with a T=1 symmetry, about 30 nm in diameter, and consisting of 60 capsid proteins.  The capsid encapsulates the genomic DNA.  Capsid protein is involved in attachment and entry into the host cell (By similarity).
What are the official names of this protein?
Capsid protein.
What is the protein family that this protein belongs to?
Belongs to the anelloviridae capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: DAPH_CLOBK
Sequence: MSYNLTDPYEIARYIKEAKKSTPIKAYIEGDLSNCDFTNIEKFNSGDLYILFGESEEILVIIENNKDKIKNCRIEQDRRKSAIPLLDMLKVNARIEPGAIIRDKVLIGENAVIMMGAVINIGAEIGEGTMVDMNAVVGARGKLGKNVHLGAGAVVAGVLEPPSSDPCTIEDNVLIGANAVILEGVKIGKGSVVAAGSIVTTDVPENVVVAGAPAKIIKEVDVKTKDKTKLLDDLRK
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. DapH subfamily.
Protein: FOL1_YEAST
Sequence: MSKLFSTVNSARHSVPLGGMRDYVHIKKLEMNTVLGPDSWNQLMPQKCLLSLDMGTDFSKSAATDDLKYSLNYAVISRDLTNFVSKKKNWGSVSNLAKSVSQFVMDKYSGVECLNLEVQADTTHIRSDHISCIIQQERGNPESQEFDVVRISELKMLTLIGVFTFERLKKQYVTLDIKLPWPKKAELPPPVQSIIDNVVKFVEESNFKTVEALVESVSAVIAHNEYFQKFPDSPLVVKVLKLNAITATEGVGVSCIREPREIAMVNIPYLSSIHESSDIKFQLSSSQNTPIEGKNTWKRAFLAFGSNIGDRFKHIQMALQLLSREKTVKLRNISSIFESEPMYFKDQTPFMNGCVEVETLLTPSELLKLCKKIEYEELQRVKHFDNGPRTIDLDIVMFLNSAGEDIIVNEPDLNIPHPRMLERTFVLEPLCELISPVHLHPVTAEPIVDHLKQLYDKQHDEDTLWKLVPLPYRSGVEPRFLKFKTATKLDEFTGETNRITVSPTYIMAIFNATPDSFSDGGEHFADIESQLNDIIKLCKDALYLHESVIIDVGGCSTRPNSIQASEEEEIRRSIPLIKAIRESTELPQDKVILSIDTYRSNVAKEAIKVGVDIINDISGGLFDSNMFAVIAENPEICYILSHTRGDISTMNRLAHYENFALGDSIQQEFVHNTDIQQLDDLKDKTVLIRNVGQEIGERYIKAIDNGVKRWQILIDPGLGFAKTWKQNLQIIRHIPILKNYSFTMNSNNSQVYVNLRNMPVLLGPSRKKFIGHITKDVDAKQRDFATGAVVASCIGFGSDMVRVHDVKNCSKSIKLADAIYKGLE
What is the function of this protein?
Catalyzes three sequential steps of tetrahydrofolate biosynthesis.
What are the official names of this protein?
Folic acid synthesis protein FOL1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DHPS family.
What are the subcellular locations of this protein?
Mitochondrion membrane.
Protein: RISB_ECOLI
Sequence: MNIIEANVATPDARVAITIARFNNFINDSLLEGAIDALKRIGQVKDENITVVWVPGAYELPLAAGALAKTGKYDAVIALGTVIRGGTAHFEYVAGGASNGLAHVAQDSEIPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVLKAIKA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: SAE1_HUMAN
Sequence: MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTKVAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDYFLLQVLLKFRTDKGRDPSSDTYEEDSELLLQIRNDVLDSLGISPDLLPEDFVRYCFSEMAPVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGMKGNGIVECLGPK
What is the function of this protein?
The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4.  It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.
What are the official names of this protein?
SUMO-activating enzyme subunit 1, Ubiquitin-like 1-activating enzyme E1A.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-activating E1 family.
Protein: DNAJ_BUCAI
Sequence: MAKKDYYQILGIPKSAEEREIKKAYKKLAMKYHPDRNQGDKTAEGKFKEIKEAYEILINEEKRSAYDQYGHAAFENGQSNSTYSTFTNSADFSDIFGDVFGDIFGGNRTQRAKKGADLCYNMEITLEEAVKGIKKEIQIPTLQKCKTCYGSGTRTGTKPRSCSTCHGKGQIHIRKGFFTVQQSCPTCHGKGTIITDPCNLCHGQGRVETYKILSVKIPPGLDTNDRIRLNNEGEAGANGAQSGDLYVQITVKKHPIFEREGNNLYCEVPINFTMAALGGEIEVPTLDGRVKLKIPYETQSGKLFRIRGRGVKSVQNRNQGDLLCRVVVETPVNLNEQQKNLLHELGNSFHGFRGEKNSPRSKRFFDGVKRFFDDLTR
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.