PharMolix/UniProtQA huggingface dataset:
Protein: ANEE_ASPA1
Sequence: MTKDNEEKTYSEVEFLTVDGLKLRGRLYLGEANGPALVMAHGFNAVKEIVIPWAAEVFQKNGISVLLFDPRNYGESEGMPRQEVDPEKQIEDYFDAVTFLRQQPGIDPEAIGLWGVSTSGATAIGAACFDKRVRLIISVCPLIEATFREEMVPDVMAQIIREREALVAARTAGQQSPQPTLVPMINQVGVSPMGFNAIHGKNFYEEMPWFKETAPNFRPHTTTLTYYKMLRWHPLSNIRCLSPTPIQMLIPGKDDVCPTQEQLDFFEALPGPKRMEYYEDRNHHGLLLGSAFEGVMEAQVRFVQDVLAGKFALKSGSQ
What is the function of this protein?
Thiohydrolase; part of the gene cluster that mediates the biosynthesis of aculenes, a unique type of norsesquiterpenes that contain a nordaucane skeleton linked to an L-proline moiety and are of mixed biosynthetic origin (PubMed:31618514).  The pathway begins with the synthesis of dauca-4,7-diene by the terpene cyclase aneC using farnesyl pyrophosphate (FPP) as substrate (PubMed:31618514).  The cytochrome P450 monooxygenase aneF then performs the initial oxidation at C-12 of dauca-4,7-diene to yield asperaculane D (PubMed:31618514).  Asperaculane D is substrate of the cytochrome P450 monooxygenase aneD for C-10 hydroxylation to yield asperaculane E (PubMed:31618514).  The cytochrome P450 monooxygenase aneG then converts asperaculane E into aculene D via C-2 oxidation (PubMed:31618514).  The monomodular nonribosomal peptide synthtase aneB adenylates L-proline and the thiohydrolase aneE transfers this activated L-proline derivative to aculenes D and C to produce respectively aculenes B and A (PubMed:31618514).  The dioxygenase aneA converts aculene D into aculene C, and aculene B into aculene A by introducing the 5,6-alkene moiety (PubMed:31618514).  Asperculanes A, B, C and F, as well as 14-prolyl asperculane C, might be shunt products of the pathway (PubMed:31618514).
What are the official names of this protein?
Thiohydrolase aneE, Aculenes biosynthesis cluster protein E.
What is the protein family that this protein belongs to?
Belongs to the polyketide transferase af380 family.
Protein: TPO_MOUSE
Sequence: MELTDLLLAAMLLAVARLTLSSPVAPACDPRLLNKLLRDSHLLHSRLSQCPDVDPLSIPVLLPAVDFSLGEWKTQTEQSKAQDILGAVSLLLEGVMAARGQLEPSCLSSLLGQLSGQVRLLLGALQGLLGTQLPLQGRTTAHKDPNALFLSLQQLLRGKVRFLLLVEGPTLCVRRTLPTTAVPSSTSQLLTLNKFPNRTSGLLETNFSVTARTAGPGLLSRLQGFRVKITPGQLNQTSRSPVQISGYLNRTHGPVNGTHGLFAGTSLQTLEASDISPGAFNKGSLAFNLQGGLPPSPSLAPDGHTPFPPSPALPTTHGSPPQLHPLFPDPSTTMPNSTAPHPVTMYPHPRNLSQET
What is the function of this protein?
Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells.  It acts at a late stage of megakaryocyte development.  It may be the major physiological regulator of circulating platelets.
What are the official names of this protein?
Thrombopoietin, C-mpl ligand, ML, Megakaryocyte colony-stimulating factor, Megakaryocyte growth and development factor, MGDF, Myeloproliferative leukemia virus oncogene ligand.
What is the protein family that this protein belongs to?
Belongs to the EPO/TPO family.
What are the subcellular locations of this protein?
Secreted.
Protein: GLPK_VIBVY
Sequence: MTEQKYIVALDQGTTSSRAVVLDHDANIVSVSQREFTQIYPQAGWVEHDPMEIYATQSSTLVEALGKKGIRSDQVAAIGITNQRETTIVWNKETGKPVYNAIVWQCRRTADICEDLKARGLESYIRENTGLVLDPYFSGTKVKWILDNVEGAREDAEAGKLLFGTVDTWLVWKMTQGRVHVTDYTNASRTMLFNINDLCWDSKLLEEMGIPASMMPEVKRSSEIYGQTNIGGKGGTRIPISGIAGDQQAALYGQMCVEAGQAKNTYGTGCFLLMNTGQEKVTSRNGLLTTLACGPKGEPAYALEGAVFMGGASIQWLRDELKLISDAHDSEYFATKVDTSNGVYVVPAFTGLGAPYWDAYARGTIVGLTRGVNSNHIIRATLEGIAYQTRDVLDAMQADSGIKLSALRVDGGAVANNFLMQFQSDVLDTEVHRPKVTEVTALGAAYLAGLAVGYWNSIDELQGKAEIDRSFLPHQDEEKRSRRYKGWKRAVKCAQTWSELRDLED
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: MIX2_XENLA
Sequence: MNGFSQQLEDFYPSYFSPSPLGFSEPEVQPVAMNLVPTIQKDIQQQPNRKEVTKIPRASEQSPVQNVRPKEAINTKEADSRNPEPDSSLVSASQRRKRTFFTQAQLDILEQFFQTNMYPDIHHREELARHIYIPESRIQVWFQNRRAKVRRQGAKATKPALASHHYSSTSGAMFPSAPAPNSSSYQMTSSRAQVQPPKEYQLNKFHQSQGFLSYPDSSSDVSRQRFLLSQATPGVYHLPQASSNVYDQNVKSNDPLWGQQQVYTNMESVLNLSRRPQQMPAQPMFMNSFQTNKIIKSKMDTTSPPIPVSTTSSHHSQMSLFAGQDPCHMSTAPGGTYGQISPISDSGVSDTSPEPSSDWEENVSVLLHL
What is the function of this protein?
May be a transcription factor which play a regulatory role in the development of the embryo.
What are the official names of this protein?
Homeobox protein Mix.2.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL22_SHIBS
Sequence: METIAKHRHARSSAQKVRLVADLIRGKKVSQALDILTYTNKKAAVLVKKVLESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: ALF1_SYNY3
Sequence: MMTLEPNQEQLKKMKSHPGFIAALDQSGGSTPGALADYGIEPNTYSGDDQMFALVHQMRTRIMTSPGFTGDRILAAILFEDTMNREVDGEPTANYLWQNKQIVPILKVDKGLAQEKDGSQLMKPIPQLDSLLMKAKKKGIFGTKMRSFIKHANPAGIEAIVDQQFELAQQIIAAGLVPIIEPEVDIHCSEKAQAEALLKQAMLKHLNQLPKGQWVMLKLTLPEQDNLYSNCIEHANVLRVVALSGGYSQAEANERLSRNHGVIASFSRALTEGLTAQQTDAEFNTMLDESIEKIYQASIT
What are the official names of this protein?
Fructose-bisphosphate aldolase class 1, Fructose-bisphosphate aldolase class I, FBP aldolase.
What is the protein family that this protein belongs to?
Belongs to the class I fructose-bisphosphate aldolase family.
Protein: FABZ_EHRCR
Sequence: MQFNIQEIIKMIPHSYPFLLIDRVTACTPNESVTAIKNVTFNEPFFIGHFPGNPIMPGVLIVEAMAQACIICTMSSMQNYSVYLMSIELAKFRKPVIPGDTLILTVNVVHKRKNTCKFECHAHVEGTLVAEAQILAMTKQNEA
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS9_SYNC1
Sequence: MAEQRFYATGKRKTSIARVWLKPGEGNITVNRRTLDEYFGRETSKMVIRQPLELTDNMGKFDIMVNVCGGGPSGQAGAIKHGITKALLEADPELRGVLKKAGFITRDSRAKERKKYGRKGARARFQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: CYB_PLAGI
Sequence: MTNLRKTHPLMKIINHSFIDLPAPSNISAWWNFGSLLGICLVIQILTGLFLAMHYTSDTLTAFSSVAHICRDVNYGWLIRNLHANGASMFFMCLYIHVGRGFYYGSYLNKETWNIGVILLLTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTTLAEWIWGGFAVDKATLTRFFAFHFILPFIITALVIVHLLFLHETGSNNPSGINPDSDKIPFHPYYTIKDALGLMFLLLTLLMLALFSPDSLGDPDNFSPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLASILILLIIPFLHTANQRSMMFRPVSQTLFWILTANLITLTWIGGQLVEQPFIIIGQLASILYFLLILVLMPLAGLFKNYMLKLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RF1_POLAQ
Sequence: MKPSMRAKLDHLDTRLAELNSLLTSEEATKDMDAYRKLTREHSDIATVVEQFGLYKKAEADAQAAEEMRKDPEMKDFADEEQKQAQATMEELEGALQKLLLPKDVNDERNVFLEIRAGTGGDESALFAGDLLRMYTRFAERQGWKVEVVNAAESDLGGYKEVVLRLVGQSVYSRLKFESGGHRVQRVPQTETQGRIHTSACTVAVMPEADELEAVKINPAELRIDTFRASGAGGQHINKTDSAVRITHIPTGTVVECQDDRSQHRNREQAMKVLVSRIMDAREREKHQLEAQTRKSLIGSGDRSDRIRTYNFPQGRITDHRINLTLYKIDAMMDGDIDDLCNALASEHQAELLAALGDS
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAA_LACLM
Sequence: MSDTTLEKIIVLDYGSQYNQLIARRIREIGVFSELMSHKVTAKEIREINPIGIILSGGPNSVYDEGSFDIDPEIFELGLPVLGICYGMQLMSYKLGGMVEAAGEREYGVAPLQLTEKSALFAGTPEVQDVLMSHGDRVTAIPEGFHVVGTSPNSPFAAVENTERNLYGIQFHPEVRHSVHGTEMLRNFALNICGAKGNWSMENFIDMQIKDIREKVGDKKVLLGLSGGVDSSVVGVLLQRAIGDQLTSIFVDHGFLRKGEADQVMETLGGKFGLNIIKVDAQKRFMDKLVGLSDPETKRKIIGNEFVYVFDDEANKLEGVDFLAQGTLYTDVIESGTDTAQTIKSHHNVGGLPEDMQFQLIEPLNTLFKDEVRALGTQLGMPDEIVWRQPFPGPGLAIRVLGDLTEEKLETVRESDAILREEIAASGLERDVWQYFTVNTDVKSVGVMGDQRTYDYTLAIRAITSIDGMTADFAQLPWDLLQKISKRIVNEVDHVNRIVYDITSKPPATVEWQ
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: ADEC_CERS1
Sequence: MSRSLSECIDQGRGLVPADLVLKHGRVFDLVTGELVQTDVAICGDRIVGTFGTYAGRREIDCRGRILVPGFIDTHLHVESSLVTPFEFDRCVTPRGITTAICDPHEIANVCGLEGIRYFLEASAHLVMDLRVQLSSCVPSTHMETAGAALEAKDLAPLMDHPRVIGLAEFMNFPGVLMKDPGCMAKLEAFRGRHIDGHAPLLRGKDLNGYIAAGIRTEHEATTADEALEKLRKGMRVLIREGSVSKDLHALVSILTERHAPYLCLCTDDRNPLDIAEHGHIDHMIRTAIRLGAPPLAVYRAASLSAAEAFGLKDRGLIAPGRRADIAVLDSLEGCHAALVLAGGVVADDAAFSARSDVEPVARASVKVAEIAPEAFRCPGNRAETPVIGILPGKIITEHLTAEIEPVDGDKRPDPARDLARIAVIERHGKTGGRATGFVRGFGMARGAIASTVCHDHHNLAVVGIDYADMALAANRLRALEGGFAVAAGGEILAELALPVGGLMSLRPFEEVRDALVTLREAARSLGVTLEEPFLQLAFLALPVIPHLKITDRGMVDVDRFEILP
What are the official names of this protein?
Adenine deaminase, Adenase, Adenine aminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: PG34_MYCTO
Sequence: MSFVVAAPEVVVAAASDLAGIGSAIGAANAAAAVPTMGVLAAGADEVSAAVADLFGAHAQAYQALSAQAALFHEQFVHAMTAGAGAYAGAEAADAAALDVLNGPFQALFGRPLIGDGANGAPGQPGGPGGLLYGNGGNGGNGGIGQPGGAGGDAGLIGNGGNGGIGGPGATGLAGGAGGVGGLLFGDGGNGGAGGLGTGPVGATGGIGGPGGAAVGLFGHGGAGGAGGLGKAGFAGGAGGTGGTGGLLYGNGGNGGNVPSGAADGGAGGDARLIGNGGDGGSVGAAPTGIGNGGNGGNGGWLYGDGGSGGSTLQGFSDGGTGGNAGMFGDGGNGGFSFFDGNGGDGGTGGTLIGNGGDGGNSVQTDGFLRGHGGDGGNAVGLIGNGGAGGAGSAGTGVFAPGGGSGGNGGNGALLVGNGGAGGSGGPTQIPSVAVPVTGAGGTGGNGGTAGLIGNGGNGGAAGVSGDGTPGTGGNGGYAQLIGDGGDGGPGDSGGPGGSGGTGGTLAGQNGSPGG
What are the official names of this protein?
Uncharacterized PE-PGRS family protein PE_PGRS34.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PE family. PGRS subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DNLI_MYCVP
Sequence: MLLVDVANASADVAAMSARLAKVARIAELLRTAGRQGDARLVRVVVSWLSGELTQRQIGVGWRSVRSVPDPAAQPSLTVEDVDARFGEIGSTSGKGSQARRAALLAELFAAATAVEQVFLRRLLTGELRQGALGGVMADAVGKAAGVPSAVVRRAAMLGGDLPAVAAAAVTDGESALAQFTLQVGRPVGPMLAQTATGVADALDRFGGTALFEAKLDGARVQIHRRGDAVSVFTRSLDDVTARLPEVVDATLALPVTELIADAEAIALRPDGRPHRFQITASRFGRRGGTPDAGTQRLSVFFFDLLHADGVDLLDLPTGERIATLDATVPREQRVDRLLTSDPEAAQAFLDATLAAGHEGVMAKSPTAPYEAGRRGAGWLKVKPVHTLDLVVLAVEWGSGRRTGKLSNIHLGARDPATGGFVMLGKTFKGMTDEMLAWQTERFLELADGAAPAATADHGAAPAATADHGAADGFTVTVRPEQVVEIAFDGIQTSSRYPGGMALRFARVLCYRDDKTAAEADTIDTVRALHERAN
What is the function of this protein?
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
What are the official names of this protein?
Probable DNA ligase, Polydeoxyribonucleotide synthase [ATP].
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
Protein: YEBZ_ECOLI
Sequence: MLAFTWIALRFIHFTSLMLVFGFAMYGAWLAPLTIRRLLAKRFLRLQQHAAVWSLISATAMLAVQGGLMGTGWTDVFSPNIWQAVLQTQFGGIWLWQIVLALVTLIVALMQPRNMPRLLFMLTTAQFILLAGVGHATLNEGVTAKIHQTNHAIHLICAAAWFGGLLPVLWCMQLIKGRWRHQAIQALMRFSWCGHFAVIGVLASGVLNALLITGFPPTLTTYWGQLLLLKAILVMIMVVIALANRYVLVPRMRQDEDRAAPWFVWMTKLEWAIGAVVLVIISLLATLEPF
What are the official names of this protein?
Inner membrane protein YebZ.
What is the protein family that this protein belongs to?
Belongs to the CopD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HXD4_SHEEP
Sequence: VNSNYTGGEPKRSRTAYTRQQVLELEKEFLFNRYLTRRRRIQHTLT
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-D4, Homeobox protein Hox-8.1, OHox-8.1.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family. Deformed subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PTH_AGRFC
Sequence: MKIIAGLGNPGAQYAGNRHNIGFMAVDALQRLPSFAPWSKKFKAEISEGEIGGEKVLLMKPLTYMNLSGESVGEAMRFFKLTPADIIAIHDELDLLAGRTRIKIGGGHGGHNGLKSLDAHCGKEYRRLRLGIGHPGDKERVHGHVLGDFAKSDRVWLDPLLDAIADNAAMLVKGDDSQLMNKLALATGSKPEAEKPVKVAKPAAQSHIHQARNSAQPKKLPETGPMAEMLKRMFGKKD
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS7_RHORT
Sequence: MRQATVTRATKETEITVWLDLDGTGQYEVSTGIGFLDHMLEQVSRHSLMDLRVHAKGDTHIDFHHTTEDTGLAIGQAVTQALGDRKGIQRYGSALIPMDEALTQVAVDLSNRPYLIWKVDFSRDKLGDMDTELFKEWFQAFSQTAGVTLHVANHYGENNHHIVESCYKALARALRQAWEIDPRKADAVPSTKGVLGGTL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPB_MYCS2
Sequence: MRVGVLGARGKVGATMVAAVEAAEDLTFSAGVDAGDDLSLLTESKTEVVIDFTHPDVVMDNLKFVIDNGIHAVVGTTGFTWERIEQVEAWVKAKPGASVLIAPNFAIGAVLSMHFAKQAAKYFESVEIIELHHPHKADAPSGTAARTAKLIAEARKGLPPNPDATSTGLDGARGADVDGIPVHSVRLAGLVAHQEVLFGTQGETLTIRHDSLDRTSFVPGVLLAVRKISGLQGLTVGIEPLLDLS
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDOR1_SCHPO
Sequence: MKNSHIYILYGSETGTAEGLAESLFRSLTRMGYDVLVNSMDDFNLENLLRPLQCVFICSTTGQGEMPLNMRKFWRFLLRKKLPNTFLNDMQYAVFGCGDTSYTRFNWASKKLDSRLRQLGAQSFSSRGEGDEQHPDGVEGVFAYWCNHLYSQLAAIKTPSRPAFGEFDLLPPSFQIIIDESLGCKVKGFEDNNIVRHSRGKIEATLVHNKRISNIKHWQDVRHLAFKIPNFERWKPGDVAVLYPWNDDMSVNSFIECMGWESIKYSPLIISSNVAERKLPWFPNILNVFNLVKYVLSIHSVPSRTFFEMASHFSNNKMHKERLQEFSSYKNIDDYYDYTTRPRRTVLETLQEFKSVQIPIEYALDAFPVIRGRQYSIANRCDNSTGILELAVALVKYQTILKSPRQGICSRWICDLHENTSFNIDILPGFLNLSYQSNKPLIMVGPGTGVAPLRALIQERIYNGLKENLLFFGCRNKSMDFLFEKDWEKYTEEGTLKLFCAFSRDQEKKKYVQHSIQENGELVYNLLNEKDGMFFVSGSSGKMPSSVKDAIAGIVSKYSGCSISDGYSFVTSLEKKNRYYQETW
What is the function of this protein?
NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.  Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of dre2, another key component of the CIA machinery.  In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins.  Positively controls H(2)O(2)-induced cell death.
What are the official names of this protein?
NADPH-dependent diflavin oxidoreductase 1, NADPH-dependent FMN and FAD-containing oxidoreductase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Note=Relocalizes to mitochondria after H(2)O(2) exposure.
Protein: NDHI_SYNJB
Sequence: MTFLKRVKEYVGDAFRAAKYIGQGMGVVFDHMGRRPVTVQYPFEKLIPSERFRGRIHFEFDKCIACEICVRVCPIDLPVVDWAYNPELKKKELYSYSIDFGVCIFCANCVEFCPTNCLSVTEDYELATYDRHDLNYHQVAMGRLPSKVTEDPMVTPLREFAYLPKGVIDPHDLPAGSQRAGKRPEEILAEMRAAKAAKEAEAKAAKAAAE
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, NAD(P)H dehydrogenase I subunit I, NDH-1 subunit I, NDH-I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: KBP_DROME
Sequence: MVIPKEILSDFKELYEKANRLVEEESRNDPPTDPFRSHYKARDVLIVLKKQLDDQLVSVQASEEDGGQDDRCYHSLLAFVCRDLGRIYIYTEEQAEGEKMLNRCLELVTPFKECPEGIIPFIGAINELSIVLASKEEYNKGLEILLEAEKIYEDFKASGLKPLAIQDVFNPPEEGQQSHEAGPKELESLYTLVSFYMAQMYGHLGEPEKSAKCCHRTLHRQLESKTYDPIDFALNTATLSQFYIGEKRFEEARHHLAAATLIMAEYEVHMLEPEMSEKQRQDVSETFKHRYADVARCWAKYGLYLMNTSKLRLMRDEDDEDAKNLEIVLRNMRLVEAEQSRFPGLDLTACENRISCEYCLTFDDAKLVFHFVNEWLDIAKDYYKAENEATEYSKIMQDYAEAYEHIAFFEENPENQAKMQKRRAKYLEDLLDLLDPIFYMKICRECWYGAGTAHAAVMDVRLDIIRATSTPAPEDIKKVNQSCMKAIKHFESYVKSYLVKPPSEEWRPNMDVEEQRHMLYAHFHIGRIYYKLISGHPLQQLEHLTSCHTYYQRFDAGCQLHKEAAETLQGEIGVVREMLQLLPLKINTIKARLNKAGLTA
What are the official names of this protein?
KIF-binding protein, Protein KBP.
What is the protein family that this protein belongs to?
Belongs to the KIF-binding protein family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: ARGB_MYCVP
Sequence: MTLTTSDKAAVLADALPWLTALNDKIVVVKYGGNAMTDDRLKAAFAADMVFLRNCGIHPVVVHGGGPQISAMLKKLGIAGDFKGGFRVTTPEVLDVARMVLFGQVGRELVNLINAYGPYAVGITGEDAHLFTAVRRTVMVDGVATDIGLVGDVERVNTDAVLDLIDAGRIPVVSTIAPDTDGLVYNINADTAAAALAEALSAEKLLMLTDVEGLYTRWPDRDSLVSQIDSDALAELLPTLEAGMVPKIEACLRAIDGGVPSAHVIDGRVEHCVLVELFTDEGAGTKVVQST
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALG10_ASPFU
Sequence: MSAVRPVSGISLAARYAVPFVLLLIPLWMAKVNTVVPDPYLDEVFHVPQAQAYWDHRWFHWDPKITTPPGLYIWSYILCAAALVLRGSPKELNAGALRATNVAAAAVFLPWRLQTLLDALRKVRNTRPSGAWLSHTVLNICLFPPLFFFSGLYYTDIVSLLAVIEAYNWDIKRSAGSWSLLKTAVFVATGLTALVLRQTNIFWVAIFLGGLQVVRRLRQSSKASQASSLLQIIQSGFNNELYDPLVSEASFFDYVKTSISLVSVGLRNFIPIIISTVPYLVILAAFGGFVLWNDGVVLGHKEFHTAGLHLSQMLYIWPYFMFFSWPILIFPVINLVLPNSVIPAFFDYGFTKKQKGLPRIWTALVIIPIMLAVVHFNTIIHPFTLADNRHYIFYVFRILRSHPAIRYAAVPTAYFVGGWAVISAFGFSTTKPQPQFVPITKSNELAAAQKGQLKEAARKKEKSERKSKSKKASQVTASPPAQDQFSPEVLARIQEHLAQRQKQQQEVPRASFVLVWLAATALSLVTAPLVEPRYFIIPWVMWRLHLPPQPVPLVYRQQRPRDEREALHADLATNFSLFMETYWFLAINAATGYIFLYKGFEWPQEPGKVQRFMW
What is the function of this protein?
Adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation.  Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol.
What are the official names of this protein?
Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase, Alpha-1,2-glucosyltransferase alg10, Alpha-2-glucosyltransferase alg10, Asparagine-linked glycosylation protein 10, Dolichyl-phosphoglucose-dependent glucosyltransferase alg10.
What is the protein family that this protein belongs to?
Belongs to the ALG10 glucosyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ENO_BIFA0
Sequence: MAAIESVYARQILDSRGNPTVEVVLDTDDGARGLGLVPSGASTGEAEAWERRDGDKSVYQGKGVLGAVKAVNEEIAPKVIGMDATDQRALDDLMIELDGTPNKGRLGANAILGVSLAALYAAAESAELPLYRYIGGTNGHVLPVPNMNIMNGGAHADFATDIQEYMISPYGFQTYSEALQAGVEVYHTLKNVLKKQGLATGLGDEGGFAPKMKTNEDSLKYIMDAISAAGYEPGKQIGIALDVASSEFYNKETGKYHFDGEDRDSEYMLDFYEKLVDQFPIVSIEDPFQEEGWEDWAKITKALGDRLQFVGDDLFVTNPVRLKKGIDMGAGNSLLVKLNQIGTVSETLDAIELATKNGFTSMVSHRSGETPDTTISDLAVAKNTGQIKTGAPARGERIAKYNRLLEIEEELGSTAEYAGYSAFKACRKYM
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: ARY2_CHICK
Sequence: MDIKEYFARISYGGSYEKPDLETLTEIFQHHIQAVPFENLSIHCGETIELDLAATYDKIVRKKRGGWCMENNHLLSWALKTLGYNVTLLGAKVYIPEHDAYADDIDHLLLKVVLHDKSYIVDGGFGMAYQLWQPMELISGKDQPQTPGIFRFVEENGTWYLEKVKRKQYVPNHSDSAPHNVDKEVCRRVYLFTLQPRDIEEFRARNLHLQTAPDSLFVTKSICSLQTPDGVRALVGWKLTEIKYNYKDNMDLVEIRILADEEMEKTLKEKFNITLDKKFVPINTSRLSLF
What are the official names of this protein?
Arylamine N-acetyltransferase, pineal gland isozyme NAT-3, Arylamine acetylase.
What is the protein family that this protein belongs to?
Belongs to the arylamine N-acetyltransferase family.
Protein: MRAZ_ECO57
Sequence: MFRGATLVNLDSKGRLSVPTRYREQLLENAAGQMVCTIDIHHPCLLLYPLPEWEIIEQKLSRLSSMNPVERRVQRLLLGHASECQMDGAGRLLIAPVLRQHAGLTKEVMLVGQFNKFELWDETTWHQQVKEDIDAEQLATGDLSERLQDLSL
What is the function of this protein?
Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster.  Acts by binding directly to DNA.  May also regulate the expression of genes outside the dcw cluster.
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: ARGB_SALPA
Sequence: MMNPLIIKLGGVLLDSEEALERLFTALVNYRESHQRPLVIVHGGGCVVDELMKGLNLPVKKKDGLRVTPADQIGIITGALAGTANKTLLAWAKKHHIASVGLFLGDGDSVNVTQLDEALGHVGLAQPGSPKLINMLLENGFLPVVSSIGVTDDGQLMNVNADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTASKAEQLIDQGIITDGMIVKVNAALDAARALGRPVDIASWRHAEQLPALFNGTPIGTRILA
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.