PharMolix/UniProtQA huggingface dataset:
Protein: ZIPA_ALIFM
Sequence: MQELRLVLILVGALAIAALLFHGLWTSRKETSSKFGKKVDIDFDSDVDDEQAAPMRGFDQPKEDVVVQKERKEPAFAREEVPTSDDPLFEGTVSSESNKFTEQEKPTVQQAQPQPVVQQVQEPAVGRIEPEAKPVAAPVKREEPTISFSAIDDEVLTQPEPIQAKVDIPETSTYLEPEIIIAEPEPEPEQDVIVINVHGMGSDRFSGNRLFNSLEQNGLVFGDMAIYHRHSDLSGAGKVLFSVANMVSPGHFQVPEGEEFSTPGISFFLPLPCYGDAEHNFKLMLQTAQMVSSELGGNVLDEKRDMLTPNKIDEYKQRVKVFCRK
What is the function of this protein?
Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring.  Also required for the recruitment to the septal ring of downstream cell division proteins.
What are the official names of this protein?
Cell division protein ZipA.
What is the protein family that this protein belongs to?
Belongs to the ZipA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type I membrane protein. Note=Localizes to the Z ring in an FtsZ-dependent manner.
Protein: TTR1_CAEEL
Sequence: MKIALSFLFLTSTFSNAGKIGRLQSVAVSGQLNCLGKPAVGVRIDLMESDNNGEETGIIDDNDFMGYTYTDSAGFFNMSGSEVEISGIEPYVNIFHKCNDGLSPCQRQLRVDIPKSATASGPAPNETFSIGTLELSSRKVIGERRSCAYRNLTQTS
What are the official names of this protein?
Transthyretin-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the nematode transthyretin-like family.
What are the subcellular locations of this protein?
Secreted.
Protein: FAHD2_XENLA
Sequence: MLTQTRVALRVLKNAHLTLPKRNISQSPALSMRLVQFQSSDSPSPRIGLELQDGGNIIDLNAYDPSLPCRMREFLEMGESALQTAKSALDSNQHILSRSNISLLAPITNPEKIICIGMNYVDHCLEQNVPVPKEPIIFNKFASSIVGPSDPIRIPEESQEVDWEAELAFVIGKKGKNIKEEDAMDHVVGYTVAHDVSARDWQMKKNGKQWLLGKTFDTFCPLGPALVTKDVISDPHNLGIRCRVNGDLVQNSNTNQMVFKTEALIAWASKFVTLNPGDVFLTGTPPGVGVFRKPPVFLKAGDVVRCEIDELGAISNPVV
What is the function of this protein?
May have hydrolase activity.
What are the official names of this protein?
Fumarylacetoacetate hydrolase domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the FAH family.
Protein: HEM3_CAUVC
Sequence: MSRQPPIRIGARGSKLSLAQSGLMQARIAHALGVPAGASKDEIEAAAPLIPIVTSGDRIQDRRLMEIGGKGLFTKEIEEALLDGRIDCAVHSLKDMPAELPPGLVLAATPEREDPRDAFISHVCERLEDLPKGARLGTASLRRQAQALHVRPDLEIVMLRGNVDTRLAKLERGEADAILLAQSGLNRLGLGHLTRSWLDPDACPPAPGQGALVIETRAEDIGAPWLEAVRCRQTTIAVAAERGALLALEGSCRTAIGARAILDGARLSMIVEALTPDGAQRFRREGDITLTGADDIAEARAFGLTLGAEVRAAGGDAIILPE
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: ISPD_BACLD
Sequence: MNYEVVIPAAGQGKRMNAGKNKLFIEAKGIPVIIHTLKVFENHDACKRIILVINEQEFGEFNTLLKTYHFKTPIEMVPGGRERQQSVFAGIKAAGKEETVLVHDGARPFIKREYIEQLVEKAKETGAAIVAVPVKDTIKRVQDGEIAGTIERSSLWAAQTPQAFRLSILMNAHLEAEAKGFLGTDDASLVEEAGGTVAIIQGDYQNIKLTTPDDLLVAEAILEAEKRNEHV
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: CAPSD_PAVCB
Sequence: MAPPAKRARRGLVPPGYKYLGPGNSLDQGEPTNPSDAAAKEHDEAYAAYLRSGKNPYLYFSPADQRFIDQTKDAKDWGGKIGHYFFRAKKAIAPVLTDTPDHPSTSRPTKPTKRSKPPPHIFINLAKKKKAGAGQVKRDNLAPMSDGAVQPDGGQPAVRNERATGSGNGSGGGGGGGSGGVGISTGTFNNQTEFKFLENGWVEITANSSRLVHLNMPESENYRRVVVNNMDKTAVNGNMALDDIHAQIVTPWSLVDANAWGVWFNPGDWQLIVNTMSELHLVSFEQEIFNVVLKTVSESATQPPTKVYNNDLTASLMVALDSNNTMPFTPAAMRSETLGFYPWKPTIPTPWRYYFQWDRTLIPSHTGTSGTPTNIYHGTDPDDVQFYTIENSVPVHLLRTGDEFATGTFFFDCKPCRLTHTWQTNRALGLPPFLNSLPQSEGATNFGDIGVQQDKRRGVTQMGNTNYITEATIMRPAEVGYSAPYYSFEASTQGPFKTPIAAGRGGAQTDENQAADGNPRYAFGRQHGQKTTTTGETPERFTYIAHQDTGRYPEGDWIQNINFNLPVTNDNVLLPTDPIGGKTGINYTNIFNTYGPLTALNNVPPVYPNGQIWDKEFDTDLKPRLHVNAPFVCQNNCPGQLFVKVAPNLTNEYDPDASANMSRIVTYSDFWWKGKLVFKAKLRASHTWNPIQQMSINVDNQFNYVPSNIGGMKIVYEKSQLAPRKLY
What is the function of this protein?
Capsid protein self-assembles to form an icosahedral capsid with a T=1 symmetry, about 22 nm in diameter, and consisting of 60 copies of two size variants of the capsid proteins, VP1 and VP2, which differ by the presence of an N-terminal extension in the minor protein VP1.  The capsid encapsulates the genomic ssDNA.  Capsid proteins are responsible for the attachment to host cell receptor TFRC.  This attachment induces virion internalization predominantly through clathrin-endocytosis.  Binding to the host receptors also induces capsid rearrangements leading to surface exposure of VP1 N-terminus, specifically its phospholipase A2-like region and nuclear localization signal(s).  VP1 N-terminus might serve as a lipolytic enzyme to breach the endosomal membrane during entry into host cell.  Intracytoplasmic transport involves microtubules and interaction between capsid proteins and host dynein.  Exposure of nuclear localization signal probably allows nuclear import of capsids (By similarity).
What are the official names of this protein?
Capsid protein VP1, Coat protein VP1.
What is the protein family that this protein belongs to?
Belongs to the parvoviridae capsid protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: RNJ_ARATH
Sequence: MMKPASLQGFSSHASSSIYSDVRRPATTPSKMAAFSALSLCPYTFTFRQSSRIKSTVSCSVTSAPASGTSSSSKTPRRRSGRLEGVGKSMEDSVKRKMEQFYEGTDGPPLRILPIGGLGEIGMNCMLVGNYDRYILIDAGIMFPDYDEPGIQKIMPDTGFIRRWKHKIEAVVITHGHEDHIGALPWVIPALDPNTPIFASSFTMELIKKRLKEHGIFVQSRLKTFSTRRRFMAGPFEIEPITVTHSIPDCSGLFLRCADGNILHTGDWKIDEAPLDGKVFDREALEELSKEGVTLMMSDSTNVLSPGRTISEKVVADALVRNVMAAKGRVITTQFASNIHRLGSIKAAADITGRKLVFVGMSLRTYLEAAWRDGKAPIDPSSLIKVEDIEAYAPKDLLIVTTGSQAEPRAALNLASYGSSHAFKLTKEDIILYSAKVIPGNESRVMKMMNRIADIGPNIIMGKNEMLHTSGHAYRGELEEVLKIVKPQHFLPIHGELLFLKEHELLGKSTGIRHTTVIKNGEMLGVSHLRNRRVLSNGFSSLGRENLQLMYSDGDKAFGTSSELCIDERLRISSDGIIVLSMEIMRPGVSENTLKGKIRITTRCMWLDKGRLLDALHKAAHAALSSCPVTCPLSHMERTVSEVLRKIVRKYSGKRPEVIAIATENPMAVRADEVSARLSGDPSVGSGVAALRKVVEGNDKRSRAKKAPSQEASPKEVDRTLEDDIIDSARLLAEEETAASTYTEEVDTPVGSSSEESDDFWKSFINPSSSPSPSETENMNKVADTEPKAEGKENSRDDDELADASDSETKSSPKRVRKNKWKPEEIKKVIRMRGELHSRFQVVKGRMALWEEISSNLSAEGINRSPGQCKSLWASLIQKYEESKADERSKTSWPHFEDMNNILSELGTPAS
What is the function of this protein?
Essential protein required during embryogenesis, especially in initiating and maintaining the organization of shoot apical meristems (SAMs), cotyledons, and hypocotyls (PubMed:15266054, PubMed:25871650).  Involved in auxin-mediated pathways during embryogenesis (PubMed:25871650).  RNase that has both endonuclease and 5'-3' exonuclease activities.  Involved in RNA surveillance to prevent overaccumulation of antisense RNA (PubMed:22033332).  Probably involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay (By similarity).
What are the official names of this protein?
Ribonuclease J, RNase J, Protein EMBRYO DEFECTIVE 2746.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SYFA_MAGMM
Sequence: MTMRNALQQLEQEAISAISSSENLKDLEDVRIRFMGKKGSITQQYGLMKTCPPEDKKELGQWLNQLKEAYNQSFEAQLEKLKKDELHARLLSERLDISLPGRHTHTGGIHPVTRAIEEIAQVFAGMGFEVASGPEIESDWHNFGALNIPDDHPAREMHDTFYIADDPNGGRRVLRTHTSPVQIRVMENRQPPLRVIAPGKVYRCDSDVTHTPMFHQVEGFMVDKGVHFGQLKGLLESFLQTFFEQKLPVRFRPSFFPFTEPSAEVDMACLFCNGKGCRICKGTGWLEVLGCGMIHPEVMKNVGMDSEIYAGFAFGMGVERLGMLKYGINDLRTFFENDVRFLSRHAVY
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNX_BACAA
Sequence: MSIQVFCDFDGTITNNDNIMSIMEKFAPPEAEEVKNRILSQELSIQEGVSQLFQLIPTNLHDEIIQFLIETAEIRNGFHEFIQFVNENNISFYVISGGMDFFVYPLLQGLIPKEQIYCNETDFSNEYITVNWPHPCDRLCQNHCGLCKSSLIRKLSDTNDFHIVIGDSITDLQAAKQADKVFARDFLITKCEENHISYTPFETFHDVKTELKHLLEVKL
What is the function of this protein?
Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase, HK-MTPenyl-1-P phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MtnX family.
Protein: GLN1B_PHOLP
Sequence: TTPQEVLSRIKDQGIKLIDLKFI
What is the function of this protein?
Involved in nitrogen metabolism via ammonium assimilation.  Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
What are the official names of this protein?
Glutamine synthetase, GS, Glutamate--ammonia ligase, Glutamine synthetase I beta, GSI beta.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBPM_COXB1
Sequence: MTKQIIKGIIIERSSPLKIDELSQAVHLRREIIIEMVEHRLIEPEGSSPTSWKFDNVCLKRAKIAASFYRDLEINMPGIAIALDLLDKIEHLEQRLRTLERFENQE
What is the function of this protein?
Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA.  Together with CbpA, modulates the activity of the DnaK chaperone system.  Does not inhibit the co-chaperone activity of DnaJ.
What are the official names of this protein?
Chaperone modulatory protein CbpM.
What is the protein family that this protein belongs to?
Belongs to the CbpM family.
Protein: GSPJ_KLEOK
Sequence: MSRCRERGFTLLEMLLALAIFAALSLSAFQILQGVMRNDEMAQRQVQRLTELQRAFVYLEGDFGQIIPRPPRGDERLFYAARYQRQSADWSISFMRNGWQNPMGILPRSELQRVGYRLRHQQLERLSYVHTDPQAGEEPIVKVLLKDVSAFRLRFFANGMWRDSWNDTTRLPEGIEVSLVVADVGEVSRLFFVTTGEQA
What is the function of this protein?
Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.  Part of the pseudopilus tip complex that is critical for the recognition and binding of secretion substrates.
What are the official names of this protein?
Type II secretion system protein J, T2SS protein J.
What is the protein family that this protein belongs to?
Belongs to the GSP J family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: LFTR_SHEDO
Sequence: MKSLCYLNQEDCFPAAHKALTDPNGLIAIGGDLQPERLLSAYQQGIFPWFNQGEPILWWTPDPRAVFQLSDYRPSRSLMKTLKRQTWRFTINKAFDAVIHQCAALRQEGTWITPAIKAAYGQLHAQGDAHSIEVWQGEQLVGGLYGIAVGKIFCGESMFHLETDASKAAFHLLVTHLRRFEFTLIDAQVMNPHLARLGAKPLPREAFLTQLAQLKHQHSPATAWQPQEVKLGY
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ORML1_DANRE
Sequence: MNVGVAHSEVNPNTRVMNSRGIWLTYALGVGMLHIVLLSIPFFSVPVVWTLTNVIHNFGMYVFMHAVKGTPFETPDQGKARLLTHWEQLDYGVQFTSSRKFFTISPIILYFLASFYTKYDTAHFVINTASLLSVLIPKLPQLHGVRIFGINKY
What is the function of this protein?
Negative regulator of sphingolipid synthesis.
What are the official names of this protein?
ORM1-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the ORM family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PRMA_VIBPA
Sequence: MPWIQIKLNATNENAEQIGDMLMEETGALSVTFLDAQDTPVFEPLPGETRLWGDTDILALYDAEADTNFIIDQIKASNMLAENFAYKVEQLEDKDWEREWMENFHPMKFGERLWICPSWREVPEPDAVNVMLDPGLAFGTGTHPTTALCLEWLESMDLSGKTVIDFGCGSGILAIAAIKLGAEKVIGIDIDPQALLASKDNAERNGVADKLEVYLPQNQPEGLIADVVVANILAGPLRELAPIIKGLVKPNGALAMSGVLDTQAEDVASYYRDELHIDPIVEQSEWCRISGRKQG
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIP2_ARATH
Sequence: MESPGRKVLYEIRHHASLPYVPRYPPLPQADGTNSKGGLRSLVSIKGVSQLKEKWSEYWNPKKTNKPVSLFISPRGELVAVTSGNHVTILRKDDDYRKPCGNFTSSISGSFTSGVWSEKHDVLGLVDDSETLFFIRANGEEISQVTKRNLKVSAPVLGLMEDDSDLQPSCLCSFSILTSDGRIHHVEISREPSASAFSKHASNSVSKQFPNHVFCFDYHPDLSFLLIVGSVAGISSSGSSGSSCISLWRKCQNLGLELLSTTKFDGVYCENKDDQLAYPKTLISPQGSHVASLDSNGCVHIFQLDKARLTLSCCPSEDSSDSLKPDKSLQSWKESLRNVVDFTWWSDHALAILKRSGNISIFDISRCVIVQEDATIYSMPVVERVQKYEGHIFLLESSTQEAKSALANVDRDASEFHHTSEHSMLWRLISFTEKTIPEMYKILVEKCQYQEALDFSDSHGLDRDEVFKSRWLKSEKGVSDVSTILSKIKDKAFVLSECLDRIGPTEDSMKALLAHGLYLTNHYVFAKSEDQESQQLWEFRLARLRLLQFSERLDTYLGISMGRYSVQDYRKFRSNPINQAAISLAESGRIGALNLLFKRHPYSLVSFMLQILAAIPETVPVETYAHLLPGKSPPTSMAVREEDWVECEKMVKFINNLPENGKNDSLIQTEPIVRRCLGYNWPSSEELAAWYKSRARDIDSTTGLLDNCICLIDIACRKGISELEQFHEDLSYLHQIIYSDEIGGEICFSLSLAGWEHLSDYEKFKIMLEGVKADTVVRRLHEKAIPFMQKRFLGTNNQNVESFLVKWLKEMAAKSDMDLCSKVIDEGCIDLYTVCFFKDDVEAVDCALQCLYLCKVTDKWNVMATMLSKLPKINDKAGEDIQRRLKRAEGHIEAGRLLEFYQVPKPINYFLEVHLDEKGVKQILRLMLSKFVRRQPGRSDNDWACMWRDLRQLQEKAFYFLDLEFVLTEFCRGLLKAGKFSLARNYLKGTGSVALPSEKAESLVINAAKEYFFSAPSLASEEIWKARECLNIFSSSRTVKAEDDIIDAVTVRLPKLGVSLLPVQFKQVKDPMEIIKMAITGDPEAYLHGEELIEVAKLLGLNSSEDISSVKEAIAREAAIAGDMQLAFDLCLVLTKEGHGPIWDLGAAIARSPALEHMDISSRKQLLGFALGHCDDESISELLHAWKDFDLQGQCETLGMLSESNSPEFQKMDGVSCLTDFPQMLDGLSSDQQLDLDRAKDSISCVAKDMPVDDSVDLESLLKENGKLFSFAASHLPWLLKLGRNRKLDKSLVLDSIPGKQFVSIKATALITILSWLAKNGFAPKDELIAMITDSIIEHPVTKEEDVIGCSFLLNLVDASNAVEVIEKQLRIRGNYQEIRSIMSLGMIYSLLHDSGVECTAPIQRRELLQKNFERKQTESLADDMSKIDKLQSTFWKEWKHKLEEKMHDADRSRMLERIIPGVETERFLSHDIEYIKVAVFSLIESVKSEKKLILKDVLKLADTYGLKQSEVILRYLSSILCSEIWTNEDITAEILQVKEEILTFASDTIETISTIVYPAASGLNKQRLAYIYSLLSECYCHLAESKEASLLVQPNSSFAGLSNWYNVLKQECSRVSFIKDLDFKNISELGGLNFDSFNNEVHAHINEMNLEALAKMVETLSGLSMENSSKGLISCQDVYKQYIMNLLDTLESRRDLDFGSAESFQGFLGQLEKTYDHCRVYVRILEPLQAVEILKRHFTLVLPPNGSYMHIPDSSTWQECLILLINFWIRLADEMQEVKSSNPSLVENLTLSPECISSCFTLLIKLVMYDSLSPSQAWAAILVYLRSGLVGDCATEIFNFCRAMVFSGCGFGPISDVFSDMSSRYPTALQDLPHLYLSVLEPILQDLVSGAPETQNLYRLLSSLSNLEGNLEELKRVRLVVWKQLVIFSENLELPSQVRVYSLELMQFISGKNIKGSSSELQSNVMPWDGSAELLSSMQKTEAALNQALPDQADGSSRLTNTLVALKSSQVAVAAISPGLEISPEDLSTVETSVSCFSKLSAAVTTASQAEALLAILEGWEELFEAKNAELLPSNEATDQGNDWGDDDWNDGWETLQESEPVEKVKKECVVSAHPLHSCWLDIFRKYIALSMPENVLQLIDGSLQKPEEVIIEETEAESLTGILARTDPFLALKISLLLPYKQIRSQCLSVVEEQLKQEGIPELSSQSHHEVLLLVIYSGTLSTIISNACYGSVFSFLCYLIGKLSREFQEERITQADNRESNASSESRFISCFGQLMFPCFVSGLVKADQQILAGFLVTKFMHSNPSLSLINVAEASLRRYLDKQLESLEHLEDSFAESSDFETLKNTVSSLRGTSKEVIRSALASLSNCTNSR
What is the function of this protein?
Required for proper maturation of seed storage proteins.  Forms a complex with MAG2, ZW10/MIP1 and MIP3 on the endoplasmic reticulum that may be responsible for efficient transport of seed storage proteins.
What are the official names of this protein?
MAG2-interacting protein 2.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: ARCS_HALVD
Sequence: MTDYFEVHARDGAARIGELRLSDSVTTPAVVDDVLADAGSLWAAERELPDGSDDVLTVLPHRSLPAGSADEVRESFSVAYPDVDFPSAAVVTADTADDFGADAYVLSDAQGFVGHARAFRDNVIEAKENLPADTALVLSGVATPRNVSLLVYAGVDLVDEKLARARGLEGFYLTSDGEYFLEDLDELPCACEACRKPASEFTRADAADHNANALRAELARVRRRVRDGRLRDYVEGQARHDQWLTALFRRFDQQYSFMEQRVPVIRDSELTAASEESIDRVEIQRFADRVTKRYRNRFDNPLVLLPCSAKKPYSESQSHRQFQEAVQYRAHMVSMTSPIGVVPQELELTYPAQHYDSVVTGDWSEDEKSFVAEVLRRYLERNDYPRIIAHLPPGAYTDIVERVADDLDLDVEFTVSEHPTTTESIGNLMRTLDGEPKFTREEREHNVVKALADYQLGPDAGDALFSDVALEMTSRYPKLQVWNDAGVQLATMVPQYGVLSFTLEGAKVWRDSDAPTKTVEIDGFVPHGSVLAPGVVDADEDIRPGDEVVVEGPKAFAIGRAEMGGRELVESTRGIGVEIRHVEER
What is the function of this protein?
Is responsible for the final step in the biosynthesis of archaeosine, a modified nucleoside present in the dihydrouridine loop (D-loop) of archaeal tRNA.  Catalyzes the conversion of 7-cyano-7-deazaguanine (preQ0)-modified tRNA to archaeosine-tRNA, transforming a nitrile group to a formamidine group.
What are the official names of this protein?
Archaeosine synthase, Glutamine:preQ0-tRNA amidinotransferase.
What is the protein family that this protein belongs to?
Belongs to the archaeosine synthase type 1 family.
Protein: RS19_SALTI
Sequence: MPRSLKKGPFIDLHLLKKVEKAVESGDKKPLRTWSRRSTIFPNMIGLTIAVHNGRQHVPVFVSDEMVGHKLGEFAPTRTYRGHAADKKAKKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: SRA_ECOL5
Sequence: MKSNRQARHILGLDHKISNQRKIVTEGDKSSVVNNPTGRKRPAEK
What is the function of this protein?
Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein.
What are the official names of this protein?
Stationary-phase-induced ribosome-associated protein, SRA, 30S ribosomal protein S22.
What is the protein family that this protein belongs to?
Belongs to the SRA family.
Protein: RL33_UREP2
Sequence: MAIKRGVRLQCNESKSINYITTKNAKNNPDRLSLNKFCPKCRKVTTHVEIKKK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RSMH_METCA
Sequence: MLSEVLEMLAVRPDGIYVDCTFGRGGHSRAILERLGPEGRLLAIDRDLEAVAAAGATGLSADARFGIEHGRFSDVGRFVGARGWTGRVDGILMDLGVSSPQLDNARRGFSFLRAGPLDMRMDPTQKTTAAEWLAEVSERELARVLRDYGEERFAGRIARAVVEERRRRPIVTTTDLVRLIEAAIPFKDKFKHPATRTFQAIRIAVNDELGQLQQGLNEAVEVLAAGGRLVVISFHSLEDRIVKRFMRDEARGREMAGGIFETRSCPRLAVLGKPLKAGDDEIRINPRARSALLRAAEKRAA
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KPTA_STRGG
Sequence: MDERRTVKVSKYLSKHLRHQPERIGLTLDENGWVAVEELLRAAARHGFAFSRAELDHVVAANDKRRFTVENGCAADGVHGDRIRANQGHTVAVDLDLPPAEPPAHLYHGTVARVMDAIRTEGLRPMARHHVHLSPDRETATRVGARRGRPLVLTVDAGAMHRAGHVFRVSANGVWLADAVPPRFLLLRG
What is the function of this protein?
Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P).  May function as an ADP-ribosylase.
What are the official names of this protein?
Probable RNA 2'-phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the KptA/TPT1 family.
Protein: FCL1_ORYSJ
Sequence: MGTVTTADPHASFLADKGGKVFVAGHRGLVGSAILRHLVSLGFTNVVVRTHAELDLTRQSDVEAFFAAELPRYVVLAAAKVGGIHANSTFPADFIAANLQIQTNVVDAALKCGSVRKLLFLGSSCIYPKFAPQPIPENSLLSGPLEPTNEWYAVAKIAGIKMCQAYRIQHGFDAISAMPTNLYGPQDNFHPENSHVLPALIRRFHEAKASNAAEVVVWGTGSPLREFLHVDDLADAVIFLMDHYSGLEHVNVGSGSEVTIKELAELVKEVVGFQGKLVWDSSKPDGTPRKLMDSSKIQEMGWKPKVPLKEGLVETYKWYVENVISAKK
What is the function of this protein?
Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
What are the official names of this protein?
Probable GDP-L-fucose synthase 1, GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase 1.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
Protein: TRMD_HELPS
Sequence: MKFSVLTLFPQLVLPYFEDSILKRALEKNLFELEVLNLRDFSANKHQKADHTLIGGGAGQILDPEMVENALHSVKNPKHTIFLSAVGKPFKQTDAMRLAQKKHVVLVCGRYEGFDERSIELGADEVFCIGDFILTGGELGALCLIDSIARHIQGVLGNAQSLENESFENHYLEAPNFANAVFKSKEINKIPAPLEYSKGNHARIKRLKLDLSKLRTKFYRLDLFKQHKS
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_METI4
Sequence: MSWKTEEVESHIPVMLKEFLKHCSPKRDEQWIDGTFGYGGHTTALLDKGCKVLALDTDEDAQKRAEILKEKGEEFYFFRKNFSEMAEACFQMGWTAVDGILLDLGVSLGQLKDPKRGFSFQFPDAPLDMRMDRTRERTGAALLNTLSKEQLVQLFSVACNMKESQKLANEIVRFRSTGPIKKVGDFLEIVTRARLLKSKINAATRPFLALRIAVNEELEHLEKALREGTKLLKGGGRIAVISFHSAEDRIVKEFMRSHCLPKKGEGVAEEENHREMFFYKVERVLVSLEERKNNPRSRSARLRIAWKIPLEEKSGL
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REP68_AAV2S
Sequence: MPGFYEIVIKVPSDLDGHLPGISDSFVNWVAEKEWELPPDSDMDLNLIEQAPLTVAEKLQRDFLTEWRRVSKAPEALFFVQFEKGESYFHMHVLVETTGVKSMVLGRFLSQIREKLIQRIYRGIEPTLPNWFAVTKTRNGAGGGNKVVDECYIPNYLLPKTQPELQWAWTNMEQYLSACLNLTERKRLVAQHLTHVSQTQEQNKENQNPNSDAPVIRSKTSARYMELVGWLVDKGITSEKQWIQEDQASYISFNAASNSRSQIKAALDNAGKIMSLTKTAPDYLVGQQPVEDISSNRIYKILELNGYDPQYAASVFLGWATKKFGKRNTIWLFGPATTGKTNIAEAIAHTVPFYGCVNWTNENFPFNDCVDKMVIWWEEGKMTAKVVESAKAILGGSKVRVDQKCKSSAQIDPTPVIVTSNTNMCAVIDGNSTTFEHQQPLQDRMFKFELTRRLDHDFGKVTKQEVKDFFRWAKDHVVEVEHEFYVKKGGAKKRPAPSDADISEPKRVRESVAQPSTSDAEASINYADRLARGHSL
What is the function of this protein?
Plays an essential role in the initiation of viral DNA synthesis.  Binds specifically to an inverted terminal repeat element (ITR) on the 3' and 5' ends of the viral DNA, where it cleaves a site specifically to generate a priming site for initiation of the synthesis of a complementary strand.  Also plays a role as transcriptional regulator, DNA helicase and as key factor in site-specific integration of the viral genome.  Inhibits the host cell cycle G1/S and G2/M transitions.  These arrests may provide essential cellular factors for viral DNA replication.
What are the official names of this protein?
Protein Rep68.
Protein: PYRG_SALPB
Sequence: MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQLAVDIGREHALFMHLTLVPYLAAAGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISMKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIYEEANPAGEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVTVNIKLIDSQDVETRGVEILKDLDAILIPGGFGYRGVEGKIATARYARENNIPYLGICLGMQVALIEFARNVAGMDNANSTEFVPDCKYPVVALITEWRDEDGNVEVRSEKSDLGGTMRLGAQQCQLSDDSLVRQLYGASTIVERHRHRYEVNNMLLKQIEAAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAANEHQKRQAK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.