PharMolix/UniProtQA huggingface dataset:
Protein: RBR_OXYRB
Sequence: MKMEDLFSLLPWLRDVPVQNQFSLDDKMYSDALKLFTESKSILSNNVSPIGSTTPEELERYMFAFILYASKRLGAKTTGDASEGSNQSGITLCQKLKAVKLNLVDFFKELPQFVVKIGPILSDMYGADWEKRLEAKELQANFVHLSLLSKYYKRAYQEFFKTNEVDKEVADPGTSSSDSISDYYRFGWLLFLALRVHAFSRFKDLVTCTNGIVSVLAILIIHIPARLRKFSALDLPLFEKKIDRGVNLVASLCQKYDTSEDEVKHMMEKANELILEILKKNPCSASLCKTENLENIDPDDLTYFEDLLEDSSLPNCISMLEKDYDAAIWNKGDIDERVFVNVDDSLLGSGSLSGGAINISGLREIRCNGLFNETIASPLSPCRSPALHVNGARGGVNIRMISTPVSTAMTTAKWLRTYISPLPSKPSPQLEKYLMSCDRNISSEVVRRAHIIMEAIFPNSALGERCIAGSLPNSNLTDNIWAQQRRLEALKLYYRVLETMCTAEAQLLHANNLTSLLTNERFHRCMLACSAELVLATHKTVTMLFPAVLEKTGITAFDLSKVIESFIRHEDSLPRELRRHLNSLEERLLESMAWEKGSSMDNSLIIARPALSAGINRFGLLAEPMPFLNAMAAHIEVSTGGLPPLPSSCKHEFAAGQNGDIRSPKRACTEYRSVLVERNSFTSPVKDRLINNLKQKLTPPALQSAFASPTRLSPGGGGETCAETGINIFFSKIVKLAAVRINGMIERLEKLEKQSQTQQLREQLRENVYCRFHIILNQRTSLFFNRHIDQIILCAFYGVAKISQYELTFKEIILNYRKQPQCKPQVFRSVFVDWSFSRRNRQGQDHVDIITFYNEVFIPSVKPLLGELGPQGACVKTDLIPESNNDKDGQCPGSPKLSTFPSLPDMSPKKVAKNVYVSPLRSSKMDALISNSSKSYYACVGESTHAFQSPSKDLTAINDRLNSTSKVRGALNFDTDAGLVSDSLVANSLYLQNGNCATTSSVGPLKTEQPDS
What is the function of this protein?
Regulator of biological processes that recruits a histone deacetylase to control gene transcription.  May play a role in the entry into mitosis, negatively regulating the cell proliferation.  Formation of stable complexes with geminiviridae replication-associated proteins may create a cellular environment which favors viral DNA replication (By similarity).
What are the official names of this protein?
Retinoblastoma-related protein.
What is the protein family that this protein belongs to?
Belongs to the retinoblastoma protein (RB) family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS4_CAUVC
Sequence: MILYPAIDLKDGQCVRLLHGDMDKATVFNTSPADQAQRFVQDGFSWLHVVDLNGAIEGKSVNTAAVEQILESISIPVQLGGGIRTLEGVEAWIEAGVSRVILGTVAVHDPELVKKAARLWPEQIAVAVDVRDGKVAVDGWTGLSDLSAIDLSRRFEDAGVAALIITDISRDGALTGVNVEGVGELADAVSIPVIASGGVAAVADIERLKARQGVEIAGAILGRSLYAGTIKPSEALIAAAA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPS_STAS1
Sequence: MIHGIGVDLIEISRIKNLYKRQSKLVDRILTINEQHKFNQFNNEQRKMEFLAGRFATKEAFSKALGSGLGKTVSFTDIDCVNDEDGKPCIHYEGYKVHVSISHTEHYAMSQVILEV
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_TRIL1
Sequence: MPIRYIDQLKDLKGKKVFIRVDFNVPQDEKGNITEDTRIAGAVPTIKYAVEQGAKVVLASHLGRPKGEKKSKYTMAPAAKRLSQLLGKKVMQAPDCFGPDVSKIIDSMKPGDVVMLENVRFYPGEEKNDPEFAQQLVNGCEIYVNDAFAVSHRAHASVEAITKLVPTIAAGFLMKNEMTFFDKAMSNPVRPLVAILGGAKVSGKLEVLETLVNKVDKIVIGGGMAFTFLKAMGYGVGKSLVEDELIPTAKKIMDKAKKKGVTFYLPVDCVVANAFEANATNFVTTVQEIPEGWMALDIGPASATLFAETLRDAKTVIWNGPMGVFEMDAFCRGTFAVAEAVGNCYATTVIGGGDTDAAVNKAGVAAKVSYISTGGGAFLELLEGKILPGVKALDVKK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMS_THEKO
Sequence: MCGIIGYIGDRKACEVIVKGLKRLEYRGYDSAGVVTGNGETLDVRKGAGRIDKLTEKLGFLEMEGNRGIGHTRWATHGVPNDINAHPQKDCTGKIVLVHNGIIENFAELKEELLKKGHVFRSDTDTEVIAHLIEEELKGSENFEEALRKALNKLRGSFALAIVYADEPDKLYVVRNESPLVLGIGEGEMFAASDVPAFLEYTNKVIFLDDGEYAILTKDSYVVKRIDTGEVVEKPVHEISWTLEMAEKAGYPHFMLKEIYEQPRAIKDAIHGNREIIRSVAEEIANYDKIIFVAMGTSYHAALVGKSLFQRLAKKVPIVEEASEFRYEFEDLIDDKTLVIAITQSGETADTLAAMKLAKKNGAKVLAVVNVVGSMATRIADLTLYTHAGPEIGVAATKTYTTQLTVLTMLAIELAKVLGTASEDYLEKLEDELMKVPELVELALKHDEALRELAETLKDKRDFFYIGRGISVPTALEGALKLKEISYIHAEGLSAGELKHGPLALLEDGVPVVAINPSGKVFDKMVSNIEEAKARGAMIISLSDREELSRVSDVLVKMPEVDELLSPIVYVVPLQLLAYHLAVLRGNDPDKPRNLAKSVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YJB6_YEAST
Sequence: MGILDSLKKPVNIKSSLPKFSRSATSINLSSHPVSSRSFLELPPELFSITKPIFKLLQAHANKIYFQSSDAEAVWNVKDSSGHVFEAESISLLGSHIIITNSSVQVADVAIIDSPSNINQCEISSVGEFLQFNNGQLSITCNDFGLLEKFKRLCMISIFEFISIYKALTGTVISSYGLRMSDMHIILNSPFNFKDWCEVYLDGQGWVKVWCHIDKVSKTNNSKSSSDNDAKGKYQIRFYRDDKSTSSKNCVFFIPDNEYVQDIFFYNINAAEPSKNMNDFFQGLQMIKLVGNVRFCSDTDFNDVVDSGSIYSSANNGSGDSSSTALNNESPNTTPKSRTFFSPKGHRRNSSHVSSLTSRSTKKPITNFTTRTNGLLIRPLPHHGVHHLEAMIRFIIPLMDCARLYGRPVQFKTERTDINSLMFGLPKLPSVDYFAEEEIAHLMTQEFNPLKEKDTDDTMALTMSRFSSYLQERMTKVSKRNTELNFRTFSDVMGMYNTTRDHSKLNCMSDKDNSVKEFSLSDKSNVSSETTNMMNQLQVNAHEYKSSMCERPIVASTSPIA
What are the official names of this protein?
Uncharacterized protein YJL016W.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THYX_MYCA9
Sequence: MAEIVPLRVQLIAKTDFIAPPDIDWSTDADGGPALVEFAGRACYQSWSKPNPRTATNESYLRHVIEVGHLSVLEHASATFYITGISRSCTHELIRHRHFSYSQLSQRFVPEDDSNVVLPPAVEDDPELVALVRKATDASRAAYVELLEKLESTLADVPNAVLRRKQARQAARSVLPNATETRIVVTGNYRAWRHFIAMRASEHADVEIRRLAIACLRQLADLAPSIFGDFDIATLADGTEVAISPLVYEG
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
What are the official names of this protein?
Flavin-dependent thymidylate synthase, FDTS, FAD-dependent thymidylate synthase, Thymidylate synthase ThyX, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase ThyX family.
Protein: Y1029_STRPN
Sequence: MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMRVLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDSLYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFFIQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPKVFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQIAGPAFYQVNTEMAEKLYQTAIDFAELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVELIPEAVENSQKNASLNKITNAHYVCDTAENAMKKWLKEGIQPTVILVDPPRKGLTESFIKASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSKLDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIELREHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI
What are the official names of this protein?
Uncharacterized RNA methyltransferase SP_1029.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
Protein: LEXA_SHESM
Sequence: MRPLTPRQAEILELIKRNIAETGMPPTRAEIATRLGFKSANAAEEHLKALAKKGCIEIMPGTSRGIRLPVEEEDNSESGLPLIGQVAAGEPILAQEHVEQYYQVDPSMFHPAADFLLRVRGDSMKNIGILEGDLLAVHKVQQARNGQVVVARVDDDVTVKRFEKKGNLVYLHAENEDYSPIKVDLSFQSLTIEGLAVGVIRNGDWL
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: ERA_PSEAB
Sequence: MTDMHDDIPAGSRCGYVAIVGRPNVGKSTLLNHILGQKLAITSRKPQTTRHNMLGIKTEGEVQAVYVDTPGLHKSGEKALNRYMNRTASAALKDVDVVIFVVDRTRWTEEDQMVLERVQYVSCPVLIAVNKTDRIEEKADLLPHLEWLTQQLPKAEVVPISAQHGTNLDVLEKLVAERLPESEHFFPEDQITDRSSRFLAAELVREKIMRQLGAELPYQITVEIEEFKQEGRILHIHALILVEREGQKKIIIGDKGERIKSIGQNARKDMEVLFDSKVMLNLWVKVKGGWSDDERALRSLGYGDL
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: KGD_MYCTA
Sequence: MANISSPFGQNEWLVEEMYRKFRDDPSSVDPSWHEFLVDYSPEPTSQPAAEPTRVTSPLVAERAAAAAPQAPPKPADTAAAGNGVVAALAAKTAVPPPAEGDEVAVLRGAAAAVVKNMSASLEVPTATSVRAVPAKLLIDNRIVINNQLKRTRGGKISFTHLLGYALVQAVKKFPNMNRHYTEVDGKPTAVTPAHTNLGLAIDLQGKDGKRSLVVAGIKRCETMRFAQFVTAYEDIVRRARDGKLTTEDFAGVTISLTNPGTIGTVHSVPRLMPGQGAIIGVGAMEYPAEFQGASEERIAELGIGKLITLTSTYDHRIIQGAESGDFLRTIHELLLSDGFWDEVFRELSIPYLPVRWSTDNPDSIVDKNARVMNLIAAYRNRGHLMADTDPLRLDKARFRSHPDLEVLTHGLTLWDLDRVFKVDGFAGAQYKKLRDVLGLLRDAYCRHIGVEYAHILDPEQKEWLEQRVETKHVKPTVAQQKYILSKLNAAEAFETFLQTKYVGQKRFSLEGAESVIPMMDAAIDQCAEHGLDEVVIGMPHRGRLNVLANIVGKPYSQIFTEFEGNLNPSQAHGSGDVKYHLGATGLYLQMFGDNDIQVSLTANPSHLEAVDPVLEGLVRAKQDLLDHGSIDSDGQRAFSVVPLMLHGDAAFAGQGVVAETLNLANLPGYRVGGTIHIIVNNQIGFTTAPEYSRSSEYCTDVAKMIGAPIFHVNGDDPEACVWVARLAVDFRQRFKKDVVIDMLCYRRRGHNEGDDPSMTNPYVYDVVDTKRGARKSYTEALIGRGDISMKEAEDALRDYQGQLERVFNEVRELEKHGVQPSESVESDQMIPAGLATAVDKSLLARIGDAFLALPNGFTAHPRVQPVLEKRREMAYEGKIDWAFGELLALGSLVAEGKLVRLSGQDSRRGTFSQRHSVLIDRHTGEEFTPLQLLATNSDGSPTGGKFLVYDSPLSEYAAVGFEYGYTVGNPDAVVLWEAQFGDFVNGAQSIIDEFISSGEAKWGQLSNVVLLLPHGHEGQGPDHTSARIERFLQLWAEGSMTIAMPSTPSNYFHLLRRHALDGIQRPLIVFTPKSMLRHKAAVSEIKDFTEIKFRSVLEEPTYEDGIGDRNKVSRILLTSGKLYYELAARKAKDNRNDLAIVRLEQLAPLPRRRLRETLDRYENVKEFFWVQEEPANQGAWPRFGLELPELLPDKLAGIKRISRRAMSAPSSGSSKVHAVEQQEILDEAFG
What is the function of this protein?
Shows three enzymatic activities that share a first common step, the attack of thiamine-PP on 2-oxoglutarate (alpha-ketoglutarate, KG), leading to the formation of an enamine-thiamine-PP intermediate upon decarboxylation.  Thus, displays KGD activity, catalyzing the decarboxylation from five-carbon 2-oxoglutarate to four-carbon succinate semialdehyde (SSA).  Also catalyzes C-C bond formation between the activated aldehyde formed after decarboxylation of alpha-ketoglutarate and the carbonyl of glyoxylate (GLX), to yield 2-hydroxy-3-oxoadipate (HOA), which spontaneously decarboxylates to form 5-hydroxylevulinate (HLA).  And is also a component of the 2-oxoglutarate dehydrogenase (ODH) complex, that catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2).  The KG decarboxylase and KG dehydrogenase reactions provide two alternative, tightly regulated, pathways connecting the oxidative and reductive branches of the TCA cycle (By similarity).
What are the official names of this protein?
Multifunctional 2-oxoglutarate metabolism enzyme, 2-hydroxy-3-oxoadipate synthase, HOA synthase, HOAS, 2-oxoglutarate carboxy-lyase, 2-oxoglutarate decarboxylase, Alpha-ketoglutarate decarboxylase, KG decarboxylase, KGD, Alpha-ketoglutarate-glyoxylate carboligase.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoacid dehydrogenase family. Kgd subfamily.
Protein: COX5A_RAT
Sequence: MLAAALRRCTAAAAARGLLHPVSAPSPAAAVCSIRCYSHGSHETDEEFDARWVTYFNKPDIDAWELRKGMNTLVGYDLVPEPKIIDAALRACRRLNDFASAVRILEVVKDKAGPHKEIYPYVIQELRPTLNELGISTPEELGLDKV
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 5A, mitochondrial, Cytochrome c oxidase polypeptide Va.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 5A family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: Y082_HAEIN
Sequence: MGLTLKEHAEVCMALAESSASAGLCYMMSNVAVNCLNLFGSYQLKQKIFSDIVQNKTFAALAYSELGTGTHFYSSFYINMAWNLVKIM
What are the official names of this protein?
Uncharacterized protein HI_0082.
Protein: TRAM_RHIRD
Sequence: MELEDANVTKKVELRPLIGLTRGLPPTDLETITIDAIRTHRRLVEKADELFQALPETYKTGQACGGPQHIRYIEASIEMHAQMSALNTLYSILGFIPKVVVN
What is the function of this protein?
Negatively regulates conjugation and the expression of tra genes by antagonizing TraR/AAI-dependent activation.  TraM may either bind or modify TraR or AAI making them unavailable.  Alternatively, TraM may bind tra promoters preventing TraR activation.
What are the official names of this protein?
Transcriptional repressor TraM.
Protein: GLGC_NITMU
Sequence: MKLPADLRSYSQITRNSIAMILAGGRGTRLRQLTDWRAKPAVPFGGKFRIIDFPLSNCVNSGIRRIGVATQYKAQSLISHIQQGWGFLDGRFQEFIELLPAQQRTEESWYQGTADAVYQNIDILRSHNPDYVLILGGDHVYKMDYAKLLADHIAKSAEMTIACIDLPLEEASAFGVMSVTKDGRVTDFTEKPSVPTAVPGRPGYALVSMGIYVFNADFLFDQLIRDHDDPNSSHDFGKDLIPHLVPRSRVFTHRFSDSCVNMVSGVPYWRDVGTVEAYWEANLDLVQVTPDLNLYDQDWPIWTHQEQLPPAKFVFDNDDRRGQALDSMVSGGCIISGATVRRSLLFSNVQVRSYSVLEDSVILPNVDVGRNARLRRVVVDKNCIIPPGLEVGFDPVEDRKHFYVTETGVTLVTPEMLGQKIHYVR
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: HIS1_METPP
Sequence: MSITLALSKGRIFEETLPLLKAAGIEVTEDPETSRKLILPTNRPDVRVVLVRATDVPTYVQHGGADLGVVGLDVLLEHGGQGLYQPLDLRIAKCRMSVAVRADFDYAAAVKQGSRIRVATKYVSVARDHFADKGVHVDLIKLYGSMELAPLTGLADAIVDLVSTGSTLKANHLLEVERIMDISSRLVVNQAALKLKREAIRPLIDAFAAAIPQE
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: M3A_CONBE
Sequence: CCKQSCTTCMPCCW
What are the official names of this protein?
Conotoxin BtIIIA, BeTXIa.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL16_LISMH
Sequence: MLVPKRVKYRREFRGNMRGRAKGGTEVAFGEYGLQAVEASWITNRQIEAARIAMTRYMKRGGKVWIKIFPHKSYTSKPIGVRMGKGKGAPEGWVSPVKRGKIMFEIAGVPEDVAREALRLAAHKLPVKTKIVKREEIGGEANES
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: SRP19_ARCFU
Sequence: MKECVVWTVNLDSKKSRAEGRRIPRRFAVPNVKLHELVEACKELGLKFRAEEKKYPKSWWEEGGRVVVEKRGTKTKLMIELARKIAEIREQKREQKKDKKKKKK
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
What are the official names of this protein?
Signal recognition particle 19 kDa protein, SRP19.
What is the protein family that this protein belongs to?
Belongs to the SRP19 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURC_BRASO
Sequence: MRLPREIGPIHFVGIGGIGMSGIAEVLCNLGYTVQGSDASDNANVARLREKGITVSVGHKAENVAGADVVVVSTAIKRDNPELMAARAQRIPVVRRAEMLAELMRLKSCVAIAGTHGKTTTTSMVAALLDAGGLDPTVINGGIINAYGTNARLGGGEWMVVEADESDGTFLKLPADVAIVTNVDPEHLDHFKTFEAVQDAFRAFVENVPFYGFAVMCIDHPVVQALVGKIEDRRIITYGVNPQADVRLVDLTPMGGGSSFKVVFRDRKSGATHEISDIVLPMPGRHNASNATAAIAVARELGLSDEAIRKAIGGFGGVKRRFTRTGEWNGVTVIDDYGHHPVEIAAVLKAARESSNGKVVAVVQPHRYTRLQSLFEEFCTCFNDADAVVVADVYPAGEAPIEGIDRDHFVLGLRAHGHRDVLPLPKAADLAGIVKDLAKPGDLVVCLGAGNITQWAYALPNELKALG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBAP1_DANRE
Sequence: MAARKSGSDIHNNGPVSYLDDVPFKLNEKFRCPSKVGLPIGFCLSDCNAILSDLQYDFNLERRTVQWGEELAKARAAEARAAEAIRTDSESERQAASQDAEVGLVGGKKARPSDEQDIVPPALKPVLAGLSHNAILTPLPAPSFGQTRPAPSNPAPQYLNLADFEREEDPFDKLELKTLDDKEELRTILQSQPQSSVSPPQLPPAEHRPVSPSTTPPLQAKTGIFHKPNGLVGLLDLDRGGVLGGQIDADRPCNIRSLTFPKLSDPGDSPLETPLSVYPVAPPRNLSNGTPPSLQRTASNNNTTLPQEQPVFAQNGTPKQSNPVTVTSHPPAGTTLLSLSPSERQCVETIVGMGYSYEGVLKAMQRQGQNVEQVLEYLFTHSRLCDRGFDATAVEECLEMYQGSEEKALEFLQLMSRFGEMGFERDTIKEVLLVHNNDQDKALEDLMTRATAS
What is the function of this protein?
Component of the ESCRT-I complex, a regulator of vesicular trafficking process.  Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs).
What are the official names of this protein?
Ubiquitin-associated protein 1, UBAP-1.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Endosome. Note=Predominantly cytosolic. Recruited to endosomes as part of the ESCRT-I complex.
Protein: PROS_DROME
Sequence: MMSSEEYEADCFGLYSDENNVLLKANEPETTAATKQQHQPQFQQQQQQQQQQQQHHHQHQQPPPSSNGHTSPIPSQVNGDGSAANCGESGKTNTNTGSHSHSNSGNTNTDADKEQEREKAKEKANEEESEDSDDDVVVVLEGCEGNASSSSSSSNSNSNASSNNHKAAATTTTTATTANHCNRSGGSSRSHRSARSSRQISQSTAVGKTTTCAAKKPTAAQATTTTAKNSNSNSNVNVNVNVNSNGSGNGNANSKVNRRSRQRSLSKDINNQPASSNSNSNSSNNSSNSNGGATATAAGFMSSAAAAAAGAAGGGALFQPQSVSTANSSSSNNNNSSTPAALATHSPTSNSPVSGASSASSLLTAAFGNLFGGSSAKMLNELFGRQMKQAQDATSGLPQSLDNAMLAAAMETATSAELLIGSLNSTSKLLQQQHNNNSIAPANSTPMSNGTNASISPGSAHSSSHSHQGVSPKGSRRVSACSDRSLEAAAADVAGGSPPRAASVSSLNGGASSGEQHQSQLQHDLVAHHMLRNILQGKKELMQLDQELRTAMQQQQQQLQEKEQLHSKLNNNNNNNIAATANNNNNTTMESINLIDDSEMADIKIKSEPQTAPQPQQSPHGSSHSSRSGSGSGSHSSMASDGSLRRKSSDSLDSHGAQDDAQDEEDAAPTGQRSESRAPEEPQLPTKKESVDDMLDEVELLGLHSRGSDMDSLASPSHSDMMLLDKDDVLDEDDDDDCVEQKTSGSGCLKKPGMDLKRARVENIVSGMRCSPSSGLAQAGQLQVNGCKKRKLYQPQQHAMERYVAAAAGLNFGLNLQSMMLDQEDSESNELESPQIQQKRVEKNALKSQLRSMQEQLAEMQQKYVQLCSRMEQESECQELDQDQDVEQEQEPDNGSSDHIELSPSPTLTGDGDVSPNHKEETGQERPGSSSPSPSPLKPKTSLGESSDSGANMLSQMMSKMMSGKLHNPLVGVGHPALPQGFPPLLQHMGDMSHAAAMYQQFFFEQEARMAKEAAEQQQQQQQQQQQQQQQQQQEQQRRFEQEQQEQQRRKEEQQQQIQRQQQHLQQLQQQQMEQQHVATAAPRPQMHHPAPARLPTRMGGAAGHTALKSELSEKFQMLRANNNSSMMRMSGTDLEGLADVLKSEITTSLSALVDTIVTRFVHQRRLFSKQADSVTAAAEQLNKDLLLASQILDRKSPRTKVADRPQNGPTPATQSAAAMFQAPKTPQGMNPVAAAALYNSMTGPFCLPPDQQQQQQTAQQQQSAQQQQQSSQQTQQQLEQNEALSLVVTPKKKRHKVTDTRITPRTVSRILAQDGVVPPTGGPPSTPQQQQQQQQQQQQQQQQQQQQASNGGNSNATPAQSPTRSSGGAAYHPQPPPPPPPMMPVSLPTSVAIPNPSLHESKVFSPYSPFFNPHAAAGQATAAQLHQHHQQHHPHHQSMQLSSSPPGSLGALMDSRDSPPLPHPPSMLHPALLAAAHHGGSPDYKTCLRAVMDAQDRQSECNSADMQFDGMAPTISFYKQMQLKTEHQESLMAKHCESLTPLHSSTLTPMHLRKAKLMFFWVRYPSSAVLKMYFPDIKFNKNNTAQLVKWFSNFREFYYIQMEKYARQAVTEGIKTPDDLLIAGDSELYRVLNLHYNRNNHIEVPQNFRFVVESTLREFFRAIQGGKDTEQSWKKSIYKIISRMDDPVPEYFKSPNFLEQLE
What is the function of this protein?
Homeodomain protein that controls neuronal identity (PubMed:1842358).  As a transcriptional factor, regulates the expression of ftz, eve and en in a subset of neuroblast progeny and modulates the transcriptional activity of other homeodomain proteins such as Dfd (PubMed:12429095, PubMed:15837198, PubMed:9380747).  Required for proper neuronal differentiation, axonal outgrowth and pathfinding of most or all neurons and their precursors in central and peripheral nervous systems (PubMed:20152183, PubMed:27510969, PubMed:1720353, PubMed:1842358, PubMed:1540176, PubMed:11051550, PubMed:18342578, PubMed:23056424, PubMed:16564014).  Regulates asymmetric stem cell self-renewal together with brat (PubMed:16564014).
What are the official names of this protein?
Homeobox protein prospero.
What is the protein family that this protein belongs to?
Belongs to the Prospero homeodomain family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cell cortex. Cytoplasm. Note=Dispersed in the cytoplasm of mitotic ganglion mother cells (GMCs) and neuroblast-like cell type.
Protein: MTR4_ARATH
Sequence: MGSVKRKSVEESSDSAPPQKVQREDDSTQIINEELVGCVHDVSFPENYVPLAPSVHNKPPAKDFPFTLDSFQSEAIKCLDNGESVMVSAHTSAGKTVVASYAIAMSLKENQRVIYTSPIKALSNQKYRDFKEEFSDVGLMTGDVTIDPNASCLVMTTEILRSMQYKGSEIMREVAWIIFDEVHYMRDSERGVVWEESIVMAPKNSRFVFLSATVPNAKEFADWVAKVHQQPCHIVYTDYRPTPLQHYVFPAGGNGLYLVVDEKSKFHEDSFQKSLNALVPTNESDKKRDNGKFQKGLVIGKLGEESDIFKLVKMIIQRQYDPVILFSFSKKECEALAMQMSKMVLNSDDEKDAVETIFASAIDMLSDDDKKLPQVSNILPILKRGIGVHHSGLLPILKEVIEILFQEGLIKCLFATETFSIGLNMPAKTVVFTNVRKFDGDKFRWLSSGEYIQMSGRAGRRGIDKRGICILMVDEKMEPAVAKSMLKGSADSLNSAFHLSYNMLLNQLRCEEGDPENLLRNSFFQFQADRAIPDLEKQIKSLEEERDSLVIEEEESLKNYYNLILQYKSLKKDIREIVFTPKYCLPFLLPNRAVCLDCTNDDEEPQSFSIEDQDTWGVIMKFNKVKSLSEDDDSRRPEDANYTVDVLTRCMVSKDGVGKKKVKAVPIKERGEPVVVTVPLSQIKSLSSAIMNIPKDLVPLEARENALKKVSELLSRHPDGIPLDPEVDMKIKSSSYKKTVRRLEALENLFEKHKIAKSPLITEKLKVLQMKEELIAKIKSLKKTVRSSTALAFKDELKARKRVLRRLGYITSDNVVELKGKVACEISSAEELTLTELMFSGIFKDAKVEELVSLLSCFVWRERLPDAAKPREELDLLFIQLQDTARRVAEVQLDCKVEIDVESFVQSFRPDIMEAVYAWAKGSKFYEVMEIARVFEGSLIRAIRRMEEVLQQLIVAAKSIGETQLEAKLEEAVSKIKRDIVFAASLYL
What is the function of this protein?
ATP-dependent RNA helicase that associates with the RNA exosome complex (PubMed:21682783, PubMed:25144737).  Required for proper rRNA biogenesis and development.  Involved in the 3'-processing of the 7S pre-RNA to the mature 5. 8S rRNA and also in the removal of rRNA maturation by-products (PubMed:21682783).
What are the official names of this protein?
DExH-box ATP-dependent RNA helicase DExH9, Protein MTR4 homolog, AtMTR4.
What is the protein family that this protein belongs to?
Belongs to the DExH box helicase family. SKI2 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RL23_MYCSS
Sequence: MATVTDPRDIILAPVISEKSYGLIEDNVYTFIVHPDSNKTQIKIAIEKIFKVKVDSVNTANRQGKRKRTRSGFGQRKSTKRAIVTLAAGSKPIDLFGAPA
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.