PharMolix/UniProtQA huggingface dataset:
Protein: SERA5_PLAF7
Sequence: MKSYISLFFILCVIFNKNVIKCTGESQTGNTGGGQAGNTGGDQAGSTGGSPQGSTGASPQGSTGASPQGSTGASQPGSSEPSNPVSSGHSVSTVSVSQTSTSSEKQDTIQVKSALLKDYMGLKVTGPCNENFIMFLVPHIYIDVDTEDTNIELRTTLKKTNNAISFESNSGSLEKKKYVKLPSNGTTGEQGSSTGTVRGDTEPISDSSSSSSSSSSSSSSSSSSSSSSSSSSSESLPANGPDSPTVKPPRNLQNICETGKNFKLVVYIKENTLILKWKVYGETKDTTENNKVDVRKYLINEKETPFTNILIHAYKEHNGTNLIESKNYAIGSDIPEKCDTLASNCFLSGNFNIEKCFQCALLVEKENKNDVCYKYLSEDIVSKFKEIKAETEDDDEDDYTEYKLTESIDNILVKMFKTNENNDKSELIKLEEVDDSLKLELMNYCSLLKDVDTTGTLDNYGMGNEMDIFNNLKRLLIYHSEENINTLKNKFRNAAVCLKNVDDWIVNKRGLVLPELNYDLEYFNEHLYNDKNSPEDKDNKGKGVVHVDTTLEKEDTLSYDNSDNMFCNKEYCNRLKDENNCISNLQVEDQGNCDTSWIFASKYHLETIRCMKGYEPTKISALYVANCYKGEHKDRCDEGSSPMEFLQIIEDYGFLPAESNYPYNYVKVGEQCPKVEDHWMNLWDNGKILHNKNEPNSLDGKGYTAYESERFHDNMDAFVKIIKTEVMNKGSVIAYIKAENVMGYEFSGKKVQNLCGDDTADHAVNIVGYGNYVNSEGEKKSYWIVRNSWGPYWGDEGYFKVDMYGPTHCHFNFIHSVVIFNVDLPMNNKTTKKESKIYDYYLKASPEFYHNLYFKNFNVGKKNLFSEKEDNENNKKLGNNYIIFGQDTAGSGQSGKESNTALESAGTSNEVSERVHVYHILKHIKDGKIRMGMRKYIDTQDVNKKHSCTRSYAFNPENYEKCVNLCNVNWKTCEEKTSPGLCLSKLDTNNECYFCYV
What is the function of this protein?
Protease activity is controversial (PubMed:25599609).  Has been shown in a number of studies to have protease activity towards a synthetic peptide in vitro (PubMed:13679369, PubMed:24769454, PubMed:29716996).  Has also been shown to lack protease activity towards a synthetic peptide in vitro (PubMed:25599609).
What are the official names of this protein?
Serine-repeat antigen protein 5, 111 kDa antigen, Serine protease SERA5, p126.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
[Serine-repeat antigen protein 5]: Parasitophorous vacuole. Note=Secreted in large amount into the parasitophorous vacuole. SUBCELLULAR LOCATION: [p18]: Secreted. Note=Secreted during merozoite egress from erythrocytes. SUBCELLULAR LOCATION: [p25n]: Secreted. Note=Secreted during merozoite egress from erythrocytes. SUBCELLULAR LOCATION: [p25c]: Secreted. Note=Secreted during merozoite egress from erythrocytes. SUBCELLULAR LOCATION: [p47]: Secreted. Cell membrane; Peripheral membrane protein; Extracellular side. Note=Secreted during merozoite egress from erythrocytes (By similarity). Colocalizes at the merozoite surface with human VTN (PubMed:29567995). SUBCELLULAR LOCATION: [p50]: Secreted. Note=Secreted during egress from host erythrocytes. SUBCELLULAR LOCATION: [p56]: Secreted. Note=Secreted during egress from host erythrocytes.
Protein: GLPK_HALVD
Sequence: MSGETYVGAIDQGTTGTRFMVFDHDGKVVANAYEKHEQIYPEPGWVEHDANEIWDNTKQVIDAALSSAGLDAEQLEAIGITNQRETTLVWDRETGQPIHNAIVWQDRRTTDRIETLEAEGKTDDVRAKTGLEPDAYFSATKAEWLLDNSDPIKLQRSRPEDIRDRAADGELAFGTIDTWLIYNLTGNHITDVTNASRTMLFNIHDMEWDDELLDEFNVPRELLPEVRPSSDDDYYGTTDADGFLGAEVPVAGALGDQQAALFGQTCFDAGDAKNTYGTGSFMLMNTGDEAVMSEHGLLTTVGFQRSGEPVQYALEGSIFITGAAIEWLEDMTLIDNAAESEKLARSVESTDGVYFVPAFTGLGAPHWDQRARGTIVGMTRGTRREHIVRATLESIAFQTRDVAEAMESDSEIDLSSLRVDGGAVKNNFLCQLQSNILDTEIVRPQVDETTALGAAYAAGLAVGYWETLDELRENWQVDREFAPKDPQNVEHRYGRWKEAVDRSLDWAREE
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.  It also catalyzes the phosphorylation of dihydroxyacetone (DHA).  Involved, together with the DHA kinase DhaKLM, in the metabolism of DHA.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: TIG_MARN8
Sequence: MQVSVETTSNIERRMTIGVPAQEIDQAVQKRLQETARTVRLNGFRPGKVPMSVVKRRFGDSIRQEVVGEAMRDNYIKALQEQDINPAGWPKLEPKTMEEGKDLEFVATFEVLPEIELGDLSKINVEKPVSEVADKDIDNMIDNLRRQQATMKEVKRKSKNKDIVTIDFKGSIDGEEFEGGSAEGHRLTLGSGQMIPGFEKGIVGGKAGEELEIDVTFPEDYHNEDLAGKDAKFAITIHKVEEPQLPELDQEFFKRFGIEAEDEVAFREEVKKNMERELKQAVSNKVKNDVVDGLLETTELEVPAALVDQEIDRLRQDAVQRFGGQVDFQQLPKEIFEEQAKRRVKTGLLFQEVVKKNDLKADEAKVEEKIQEIASTYEQPDEVVAHFNSNPDQKAQVESSVLEDAVVDFVLGAAKVKEKKMKYEEAVQAGQPQR
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: RL5_PROM9
Sequence: MTLKNRYKESIRPKLLKDLGLKNIHQVPKVVKVNVNRGLGEAASNSKSLEASLNEMATITGQKALVTRAKKAIAGFKIREGMPIGCTVTLRGDRMYSFLERFINLALPRIRDFRGVNPKSFDGRGNYTVGVKEQLIFPEISFDKIDSIRGMDITIVTSARSDQEGKALLQELGMPFSKN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: PRN1_ARATH
Sequence: MTYENNSVPRIVIKKVLAKLEKEGEGAVVRNGITKIDQKLLDPFVLLVEFSFSLSAGFPDHPHRGFESVTYMLQGGIIHKDPKGHKGTIQAGDVQWMTAGRGIIHSEFPEEEVNNGLQLWINLPSTEKMTEPKYKELSSLDIPRAEENGVEVKVIAGDSMGIKSPVYTRTPTMFLDFTLKPGSQTHQTVPESWTAFAYIIEGDEGVFGSLNSSAISAHHVVVFGPGDLVSVWNKSTSRSLRFLLIAGEPIGEPVVQCGPFVMNSQAEIDMAFDDYQNAKNGFEMAKC
What is the function of this protein?
Involved in abscisic acid signal transduction.  Plays a role in seed germination and early seedling development.  Involved in the blue light (BL) signaling.
What are the official names of this protein?
Pirin-1, AtPirin1.
What is the protein family that this protein belongs to?
Belongs to the pirin family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HSLV_HELPH
Sequence: MFEATTILGYRGEMGGKKFALIGGDGQVTLGNCVVKANATKIRSLYHNQVLSGFAGSTADAFSLFDMFERILESKKGDLFKSVVDFSKEWRKDKYLRRLEAMMIVLNLDHIFILSGTGDVLEAEDNKIAAIGSGGNYALSAARALDHFAHLEPRKLVEESLKIAGDLCIYTNTNIKILEL
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_PYRFU
Sequence: MRMLLIHSDYIEYEVKDKAIKNPEPISEEEKKGRMDEVLVAFISVEKVDEKNPDEVVEKAINEIIEVAKQVKAENLFVYPFAHLSSELAKPSVAQEVLRRIYEGLKERGYNVGKAPFGYYKAFRISCKGHPLAELSRTIVPEEAKVEEVPEALKKEETELVSYWYILTPEGELVEVDKFDFTGHENLRKFANYEIAKSRIADKEPPHVRLMLEHELVDYEPGSDPGNLRYYPKGRLIKSLLEQYVSEKVIEYGAMEVETPIMYDFEHPALEKYLNRFPARQYIVLSGDKRYFLRFAACFGQFMISKDATISYRNLPLRMYELTRYSFRREKRGELSGLRRLRAFTMPDMHTLAKDIEQAKDEFKKQFKLSMEVLGGVGLTPDDYEVAIRFTEDFWNEHKDFIIELVKLIGKPVLIEMWKQRFFYFILKFEFNFVDNLDKAAALSTVQIDVENAERFGITYYDENGEEKYPLILHCSPSGAIERVMYAILEKQAKLMQEGKKPMFPLWLSPIQVRVIPVSKEYLDYALYVAGKIEGARIRVDVDDEDERLSKKIRRAEKEWIPYIVVVGEKEKETGTITVRRREDGKQYETRIEELIKEIKQKTEGFPYKPRPLPLLLSQRPKFRG
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) (By similarity).  Also edits incorrectly charged L-seryl-tRNA(Thr) (PubMed:26113036).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MQO_PROMP
Sequence: MTSKNILNKNNCYDAILVGAGIMSGTLALLITEILPTIKILIIEKLNKPGSESTGAFNNAGTGHAANCELNYTPVDENGDLQIDKALFINRSFENSMSLWASLYSKGKIDIKKFLKFIPHISFVTGTENISFLKKRFKAMSKYPEFADMEFSSSFNQIKSWAPLITTCRDPLDKVAATRIKRGTDINFQALTREYLTYISKNKNVEIFYNTELIDLKKTDKKQWKLKVRSLGKIVSLNTSYVFLGAGGKTINFLQKSKIPEAKIYGGFPVSGKWLICEEKSLTEKHNAKVYGKADIGSPPMSVPHLDTRWIEGKKFLLYGPFAGFTTKFLKKGSYLDLFSSIKKSNLFSMLDVGIKNNELINYLFSQSFKSHNSRVENLRNMMPSAEPSNWYLENAGQRVQIIKKTKDGGSLQFGTEIVNSGDGSLSALLGASPGASTAVSIMIEVLKKSCLFNADKFELEKKLSNLLYESEIKNESDNNFLEIIKKRNNSILGFHP
What are the official names of this protein?
Probable malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: UREF_RHOP5
Sequence: MTDATDPGALSAALAAALYRLMTWLSPSFPVGAFAYSSGLEWAVEAGDIKDAATLTDWLSAMLSDGAGFCDGVVLAQAYRAASAGDDARLRAVADLACAMVPSRERHLETTTQGRAFVEIASHAWSSARLPPAIAACGGAMAYPVAVGIVSAAHEVPLAAVLHAFLHALVSNWISAAARLVPLGQTDSQRVLAALEPVVAPTAARALAASLDDLGSATFRADLASLRHESQYTRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRE3_STAAC
Sequence: MSYSIVRVSKVKSGTNTTGIQKHVQRENNNYENEDIDHSKTYLNYDLVNANKQNFNNLIDEKIEQNYTGKRKIRTDAIKHIDGLITSDNDFFDNQTPEDTKQFFEYAKEFLEQEYGKDNLLYATVHMDEKTPHMHYGVVPITDDGRLSAKEVVGNKKALTAFQDRFNEHVKQRGYDLERGQSRQVTNAKHEQISQYKQKTEYHKQEYERESQKTDHIKQKNDKLMQEYQKSLNTLKKPINVPYEQETEKVGGLFSKEIQETGNVVISQKDFNEFQKQIKAAQDISEDYEYIKSGRALDDKDKEIREKDDLLNKAVERIENADDNFNQLYENAKPLKENIEIALKLLKILLKELERVLGRNTFAERVNKLTEDEPKLNGLAGNLDKKMNPELYSEQEQQQEQQKNQKRDRGMHL
What is the function of this protein?
The interaction of the RSA site and the PRE protein may not only serves a function in plasmid maintenance, but may also contributes to the distribution of small antibiotic resistance plasmids among Gram-positive bacteria.
What are the official names of this protein?
Plasmid recombination enzyme type 3, Mobilization protein, Plasmid recombinase.
What is the protein family that this protein belongs to?
Belongs to the plasmid mobilization pre family.
Protein: RADA_CENSY
Sequence: MNIENFDLSDLEGVGPVTKKKLEDSGVHSMMDLVVRGPVELGEISSMSSEICEKIVTIARKRLAETGAITKDFASGSEIYKRRQSIGMITTGTDALDALLGGGIETQAITEVFGEFGSGKTQFCHTMCVTTQKPKEEGGLGGGVMYIDTEGTFRPERVVTIAKANNMDPAKLLDGIIVARAYNSSHQVLILEEAGKTIQEENIKLIISDSTTGLFRSEYLGRGTLASRQQKLGRYIRLLARIAETYNCAVLATNQVSSSPDSFFGDPTRPVGGNVVGHASTYRIYFRKGGKNKRVAKIIDSPHHPASEAVFELGERGVQDTEEHLKQLDKEAKKAEKEAAKPVKKSKAKAKADGPEGVDATPAIEPEGIDTAAAEPEDIGTIVSESADAGEPADPELE
What is the function of this protein?
Involved in DNA repair and in homologous recombination.  Binds and assemble on single-stranded DNA to form a nucleoprotein filament.  Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules (By similarity).
What are the official names of this protein?
DNA repair and recombination protein RadA.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RecA-like protein family.
Protein: MIAA_STRGC
Sequence: MKTKIIVIVGPTAVGKTALSIEVAKAFNGQIISGDSQQVYRGLNIGTAKIRPEEQEGISHYLLDVRDVGESYSAYDFVTEATQAIREIEAQGQLPIICGGTGLYIQSLLEGYHLGGSVPHEEILAYRAQLDSWSDEDLFGKIAELGIEIPQINRRRAMRALEIAHLGGQLENNLPDYEALLICLDDKREKLYERINQRVDLMIEDGLLEEARWLFDKAPTSQASKGIGYKELFPYFAGQVSLEEAVDKLKQNTRRFAKRQLTWFRNRMSVTFYQVGNPDYKNQVMEDIKNFLDK
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: PYRB_PROM4
Sequence: MASWNHKHIIDLAAFSLEDYQNVLELANRFKALPKSGARKLPALQGRFIAILFFEPSTRTRTSFEIAAKRLSADVQTFSASTSSLTKGETPLDTALTYVAMGADTLVIRHSSSGVPEQIAKSLEKAGKKTAILNGGDGLHSHPSQALLDLFTLVNFFEPSKPDIKSIKGKRIAIVGDILHSRVARSNLWSLTGCGADVILCGPKSLLPNDFVDFVSSPPPGQLIDPIKNRGKVMISRSLKETLQQSDAVITLRLQKERMNQNLLTNLGSYHREYGISRRILQNFRKEIPVLHPGPVNRGIEISSELLDDQSICLTQEQVKNGIPIRMALLYLLMASK
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: PPA24_ARATH
Sequence: MARVLGVLLCLLALFSSSLCLDHANGRGDQALAQINVYETSLALDSSVKLHASPQVLGSQGEDTEWVNLAISNPKPTSDDWIGVFSPAKFDSGNCWPTSGGKEKTPYICSSPIKYMYCNSHPDYMKSGNVTLKFQIINQRADVSFALFSNGVQEPHLLGVSNPVAFFNPKAPVYPRLALGKNWDEMTVTWTSGYNIDEAVPFIEWSAKGLPARRSPAGTLTFNRNSMCGNPARGVGWRDPGFFHTSFLKELWPNREYIYRLGHDLVNGSTIWSKNYTFVSSPYPGQDSKQRVIIFGDMGKGERDGSNEYNDYQPGSLNTTDQVIKDLKDIDIVFHIGDLTYSNGYLSQWDQFTAQVQPIASTVPYMIASGNHERDWPDTGSFYAGTDSGGECGVPAETMFYFPAENRAKFWYKTDYGMFRFCVADSEHDWREGTEQYKFIENCLATVDRKTQPWLIFIAHRVLGYSTNDWYGKEGTFEEPMGRESLQKLWQKYKVDLAFYGHVHNYERTCPIYESQCVNNDKDHYSGTFKGTIHVVVGGAGSHLSPFSSLVPKWSLVRDYDFGFVKLTASDHSSLLFEYKKSSTGQVYDSFNISRDYRDVLACTHDSCEPTTSAG
What are the official names of this protein?
Probable inactive purple acid phosphatase 24.
What is the protein family that this protein belongs to?
Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.
What are the subcellular locations of this protein?
Secreted.
Protein: GATB_LISMH
Sequence: MNFETVIGLEVHVELKTNSKIFSSAPAHFGAEPNTNTTVVDLGMPGVLPVLNKRAVEFGMKAAMAINCEIAEHTKFDRKNYFYPDNPKAYQISQFDKPIGEHGWIEIEVGGKKKKIGITRLHLEEDAGKNTHTSHGYSLVDINRQGTPLIEIVSEPDIRSAEEAYAYLEKLKSIIQYTGVSDVKMEEGSMRCDANISIRPIGQEEFGVKTELKNLNSFNNVRKGIEYEEKRQAEVLKSGGIIEQETRRFEEATGKTSLMRIKEGSDDYRYFPEPDLVDLFIDDAWKERIRAEIPELPDKRQIRYINDLGLPAYDAMVLTLTKEMSDFFEATLAAGADAKQASNWLMGEVSAYLNAEQKELHETGLTPENLAGMIKLIEAGTISSKIAKKVFRELAQNGGDAEQLVKDKGLVQISDEGALRTIISEILDNNEQSIVDFKNGKDRAVGFLVGQVMKATKGQANPPMVNKLLLEEMNKR
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: LEPA_GLUDA
Sequence: MTDTPLSLIRNFSIIAHIDHGKSTLADRLIQACGALTAREMTNQVLDNMELERERGITIKAQTVRLSYPAKDGKTYVLNLMDTPGHVDFAYEVSRSLAACEGSLLVVDASQGVEAQTLANVYQAIDANHEIVPVLNKVDLPAAEPERVKAQIEEVIGIPADDAVEISAKTGLNIEGVLEALVTRLPPPVGDESKPLQALLVDSWYDPYLGVIILVRIKEGRLRKGSRIRMMSNGAVYHVDQVGVFAPRMVPVDDLGPGEMGYINAAIKTVADCNVGDTITDDRHPAERALAGFKPSIPVVWCGLYPIDADDFEKLRDSLSKLRLNDASFHYEAETSAALGFGFRCGFLGLLHLEIIQERLSREFNLDLIATAPSVVYRLYRTNGGMEELHNPADMPDGSVVEKIEEPWITATIMVPDDYLGAVLTLCSERRGIQKDLTYVGTRAMAVYRLPLNEVVFDFYDRLKSVSRGYASFDYQMDGYEESDLVRISILVNQEPVDALAFIAHRSAAESRGRSICAKLKELIPRQLFKIAIQAAIGSRVIARETIGALSKDVTAKCYGGDISRKRKLLEKQKEGKKRMRQFGKVEIPQSAFLAALKMDH
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: LPXC_YERPE
Sequence: MIKQRTLKRIVQATGVGLHTGKKVTLTMRPAPANTGVIYRRTDLNPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIIIEVNAPEVPIMDGSASPFVYLLLDAGIEELNSAKKFLRLKETVRVEDGDKWAELSPFNGFRLDFTIDFNHPAIDSSTQRYCLDFSADSFVRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVVDDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVLAKQEAWEFVTFQDEAEMPLAFKAPSTVLAY
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: DEF_TERTT
Sequence: MALLPILEFPDARLRTVAKPVEQVDERVRAIIDDMFETMYDAPGIGLAATQVNVHEQIIVIDISENHDEPLVFINPRIDVLDETLFDYEEGCLSVPGFYEEVTRPRHVRVTALNRDGEEFVLEPEGLLAVCIQHEIDHLKGKLFVDYVSNIKRQRIRKKLEKQHKERA
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: BASP1_DANRE
Sequence: MGGKLSKKKKGYNVNDEKAKEKDAKTEGASAEESEAPKENKEDAAAATETTNDTAAAAKEATPTADSNSTAPKEEEKSAAPPKKEEPAANANANAPKASDAKTSEAAKAEPAKSPDAPPVKAEEKSAPSAAPANEKEPAKEAAKDPAPAVAAASESKPDAESKKTEAPPTKESAPAEPITTETSPAPNKEQAVAVQD
What are the official names of this protein?
Brain acid soluble protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the BASP1 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: NFI_ECO7I
Sequence: MDLASLRAQQIELASSVIREDRLDKDPPDLIAGADVGFEQGGEVTRAAMVLLKYPSLELVEYKVARIATTMPYIPGFLSFREYPALLAAWEMLSQKPDLVFVDGHGISHPRRLGVASHFGLLVDVPTIGVAKKRLCGKFEPLSSEPGALAPLMDKGEQLAWVWRSKARCNPLFIATGHRVSVDSALAWVQRCMKGYRLPEPTRWADAVASERPAFVRYTANQP
What is the function of this protein?
DNA repair enzyme involved in the repair of deaminated bases.  Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
What are the official names of this protein?
Endonuclease V, Deoxyinosine 3'endonuclease, Deoxyribonuclease V, DNase V.
What is the protein family that this protein belongs to?
Belongs to the endonuclease V family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WTF26_SCHKA
Sequence: MNNNYTSLKSSIDEEGELKTDHEIDLEKGLLPEYNSEEEGALPTYSDHARSSNPPNTHRENHSSGTTDDSSPFLIKLLISFTPIVLLNALAVCYLTYKDAFFKDYGAAEWTLFGFWCLVCTLALIILTYFYETWTKAVKVTAIGLFNIRREMMIIIWILWLIICCILFGCVKDGRLNLNKALIYSTCTISAVLFLIVSSVCIPMWTLWRALSGMLQVLGIHGIIALLVNGSMSLFGKHFGWRGYEIEGFVLFFTGNALFLYEMERPGVLKRMRNTTGNVIGYILEGIGNIGNAIGRIGNAFRGANDNNDIPLGEMEVESEV
What is the function of this protein?
Acts as a suppressor component of the dual wtf meiotic drive system, and can suppress but not confer meiotic drive by compatible poisons (PubMed:28631612).  Wtf meiotic drive systems promote unequal transmission of alleles from the parental zygote to progeny spores by encoding a poison and an antidote from the same locus; the poison is trans-acting and forms toxic aggregates in all spores within an ascus, wherease the antidote is spore-specific and targets aggregates for degradation by the vacuole (By similarity).  Meiotic drive by wtf systems therefore lead to poisoning of all progeny that do not inherit the dual poison/antidote allele, or express a compatible antidote (By similarity).
What are the official names of this protein?
Meiotic drive suppressor wtf26.
What is the protein family that this protein belongs to?
Belongs to the WTF family.
What are the subcellular locations of this protein?
Spore membrane; Multi-pass membrane protein. Vacuole membrane; Multi-pass membrane protein.
Protein: RUVC_CROS8
Sequence: MSIILGIDPGSRVTGYGVIRQTGRQLTYLGSGCIRTSVTDLPSRLKLIYAGVSEIITQFRPDYFAIEQVFMAKNADSALKLGQARGAAIVAAVNHDLPVFEYAARQVKQTVVGIGSAEKSQVQHMVRTLLKLSANPQADAADALAIAITHCHVSQNATQVSESRLNLARGRLR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: COX2_BOVIN
Sequence: MAYPMQLGFQDATSPIMEELLHFHDHTLMIVFLISSLVLYIISLMLTTKLTHTSTMDAQEVETIWTILPAIILILIALPSLRILYMMDEINNPSLTVKTMGHQWYWSYEYTDYEDLSFDSYMIPTSELKPGELRLLEVDNRVVLPMEMTIRMLVSSEDVLHSWAVPSLGLKTDAIPGRLNQTTLMSSRPGLYYGQCSEICGSNHSFMPIVLELVPLKYFEKWSASML
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TF2B1_THEVO
Sequence: MVENQKKKKIEEIERCPECGSTNLIRDYEHGELVCGECGAVIEDSYIDQGPEWRAFDSEQNESRARAGSPMTFTIHDKGLSTDISWKNKDSYGRSIPTRNRAQLYRLRKWQKRIKVSNAAERNLSQALQELERMAFNLSIPNDVRETAAVIYRKAVKQNMIRGRSIEGVVAGALYAACRITNVPRTLGEIASVTRVKKKEIGRTYRIMSRYLKLNIMPSKAEDYISRFCSKLKLSMDTRNKALEILRDAENVGLTSGKGPTGVAAAAIYIASLITGERRTQRAVAEVAGVTEVTIRNRYKELTEKLKLNVEQ
What is the function of this protein?
Stabilizes TBP binding to an archaeal box-A promoter.  Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
What are the official names of this protein?
Transcription initiation factor IIB 1, TFIIB 1.
What is the protein family that this protein belongs to?
Belongs to the TFIIB family.