PharMolix/UniProtQA huggingface dataset:
Protein: TRPB_LACLA
Sequence: MTYNQPNNKGFYGQFGGQFVPETLMTAVKQLEEAYVDSKKDPLFQAELKELLKDYVGRENPLYYAKRLTEYAGGAKIYLKREDLNHTGAHKINNALGQVLLAKKMGKNKVIAETGAGQHGVASATAAALFGMECTIYMGEEDVKRQSLNVFRMELLGAKVHSVTDGSRVLKDAVNAALRAWVAQVEDTHYVMGSVLGPHPFPQIVRDYQAVIGQEARAQFLEKENKLPDALVACVGGGSNSMGLFYPFVNDESVAMYGVEAAGLGIDTPHHAATITKGRPGVLHGTLMDVLQDENGQMLEAFSISAGLDYPGIGPEHSYFNAVGRAKYVDITDEEALEGFKILSRTEGIIPALESSHAIAYAVKLAKELGADKSMIVCLSGRGDKDVVQVKERLEAEKEVKK
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: HEM3_STAEQ
Sequence: MRKLIVGSRRSKLALTQSQQFIDKLKFIDPSLDIEIKEIVTKGDKIVDKQLSKVGGKGLFVKEIQNELFNKEIDMAIHSLKDVPSMIPDGLTLGCIPDREIPFDAYIAKNHIPLQELSEGSIVGTSSLRRGAQILSKYPHLKIKWIRGNIDTRLKKLETEDYDAIILAAAGLKRMGWSDNIVTTYLDRDILLPAIGQGALGIECRSDDKELLDLLSKVHNHDVAQCVTAERTFLSEMDGSCQVPIGGYATIAQDNQIEFTGLIMSPDGKERYEHTALGTDPVKLGIEVSQVLKKQGAYDIIKKLNEAE
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: NAGB_COLP3
Sequence: MQVIIFDNAQQVAENAAEWVAELINKKSNPVLGLATGSTPISLYQELVNKYKAGELSFSNTTSFNLDEYLGINEKNQQSYRHFMNENLFNHVDINKLKTFLPTCNQGENPREQGLDYEDKIAQAGGIDLQILGIGANGHIGFNEPTSSLASRTRIKTLTQQTLNDNSRLFAADEFQPTLAMTMGIATILDARYVLLMATGKSKAKAVKEMVTGPLSAVCPASSLQLHENAIVLLDKEAASELEDHEYYVWADKQNVKINQEFGLYHNY
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: CAPPA_CLOPS
Sequence: MKIPCSMMTQHPDNVETYISIQQEPAEAIKGLTPQDKGGLGIEEVMIDFEGKLTPYHQTSQIALGLISNGIIPGKDVRVTPRIPNANKESVFRQLMSIMSIIETNVQSKELTGTLAISEVVVPMIETGKEISEFQDRVNSVVDMGNKNYKTKLDLNSVRIIPLVEDVPALVNIDRILDEHYQIEKSKGHVLKDLRIMIARSDTAMSYGLISGVLSVLMAVDGAYKWGEKHGVTISPILGCGSLPFRGHFSEENIDEILATYSGIKTFTFQSALRYDHGEEATKHTVNELKAKIEESKPRNFSEEDKDLMKEFIGICSKHYLQTFLKVIDTVSFVSDFIPKNRDRLTKAKTGLEYNREVANLDNVADLVKDEVLKQEILSIDNSKEYAVPRAISFTGAMYTLGMPPELMGMGRALNEIKTKYGQEGIDKLLEIYPILRKDLAFAARFANGGVSKKIIDEEARQEYKEDMKYVNEILNLGLDYDFLNENEFYHTLLKTTKPIIMHLMGLEENVMRNSTEELKILNEWIVRMGKVRGSIG
What is the function of this protein?
Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 2 family.
Protein: SDS22_SCHPO
Sequence: MSNVSSEDGIAPETQLIIDDPDVQQIDADEDLLDDVPDDVDCVELIQSRIQSMASLGLERFKNLQSLCLRQNQIKKIESVPETLTELDLYDNLIVRIENLDNVKNLTYLDLSFNNIKTIRNINHLKGLENLFFVQNRIRRIENLEGLDRLTNLELGGNKIRVIENLDTLVNLEKLWVGKNKITKFENFEKLQKLSLLSIQSNRITQFENLACLSHCLRELYVSHNGLTSFSGIEVLENLEILDVSNNMIKHLSYLAGLKNLVELWASNNELSSFQEIEDELSGLKKLETVYFEGNPLQKTNPAVYRNKVRLCLPQLRQIDATIIPKTSKQFP
What is the function of this protein?
Essential for the mitotic metaphase/anaphase transition.  Positively modulates protein phosphatase-1, possibly by forming a repeating helical rod that is capable of enhancing a PP1-dependent dephosphorylation activity.
What are the official names of this protein?
Protein phosphatase 1 regulatory subunit SDS22.
What is the protein family that this protein belongs to?
Belongs to the SDS22 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NIS1_MAGO7
Sequence: MQLLATTLTFASGAAAYINSMSAPASVQRGQAFTAQLNSSIYVQNYDDFGVVWGLAPPNLNTSACVGCVGRRIGYTNLFGDKADVQVPPSGTVGVQVTVPADQAPGEYLLIAGASYLVGASGVTGFNYFNTTVQVCE
What is the function of this protein?
Secreted effector that induces necrotic lesions in Nicotiana benthamiana (PubMed:22352720).  Interacts with the rice receptor-like kinases (RLKs) BAK1/SERK3 and BKK1/SERK4, inhibits their kinase activity and suppresses INF1-induced pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI) in N. benthamiana (PubMed:30584105).  Also interacts with the rice receptor-like cytoplasmic kinase (RLCK) BIK1 and inhibits its kinase activity, thereby inhibiting PAMP-induced ROS generation (PubMed:30584105).  In PTI, phosphorylation relaying by RLKs and RLCKs is critical for the initiation of downstream signaling (PubMed:30584105).  Suppresses R3a/Avr3a-dependent hypersensitive response (HR) cell deat and thus may have additional targets, probably belonging to a kinase family that regulates Avr3a effector-triggered immunity (ETI) (PubMed:30584105).
What are the official names of this protein?
Necrosis-inducing secreted protein 1, Secreted effector NIS1.
What is the protein family that this protein belongs to?
Belongs to the NIS1 effector family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm.
Protein: SRS10_MOUSE
Sequence: MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKSRSRSWTSPKSSGH
What is the function of this protein?
Splicing factor that in its dephosphorylated form acts as a general repressor of pre-mRNA splicing.  Seems to interfere with the U1 snRNP 5'-splice recognition of SNRNP70.  Required for splicing repression in M-phase cells and after heat shock.  Also acts as a splicing factor that specifically promotes exon skipping during alternative splicing.  Interaction with YTHDC1, a RNA-binding protein that recognizes and binds N6-methyladenosine (m6A)-containing RNAs, prevents SRSF10 from binding to its mRNA-binding sites close to m6A-containing regions, leading to inhibit exon skipping during alternative splicing (By similarity).  May be involved in regulation of alternative splicing in neurons (PubMed:10583508).
What are the official names of this protein?
Serine/arginine-rich splicing factor 10, FUS-interacting serine-arginine-rich protein 1, Neural-salient serine/arginine-rich protein, Neural-specific SR protein, Splicing factor, arginine/serine-rich 13A, TLS-associated protein with Ser-Arg repeats, TASR, TLS-associated protein with SR repeats, TLS-associated serine-arginine protein, TLS-associated SR protein.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
Protein: GNAI_PATPE
Sequence: MGCATSAEDKAAAERSKAIDRNLRIDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEEGYSEEDCKQYKPVVYSNTIQSMIAIIRAMGSLKVDFGDGDRTDDARQLFALAGQAEEGELSPELAAVMKRLWADGGVQGCFSRSREYQLNDSASYYLNALDRLAAPGYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMNRMHESMKLFDSICNNKWFTETSIILFLNKKDLFEEKITKSPLTICFPEYTGSNTYEEAAAYIQMQFEDLNKRKDQKEIYTHFTCATDTNNIQFVFDAVTDVIIKNNLKDCGLF
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.  This G protein is involved in 1-methyladenine-induced oocyte maturation.
What are the official names of this protein?
Guanine nucleotide-binding protein G(i) subunit alpha, Adenylate cyclase-inhibiting G alpha protein.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family. G(i/o/t/z) subfamily.
Protein: RL7_THEP3
Sequence: MNKEEILEAIKNMTVLELAELVKALEEEFGVSAAAPVAVAAAPAAGAPAAAPAEEKTEFDVILQEVGSDKIKVIKVVREVTGLGLKEAKDLVESAPKPVKEGVSKDEANQIKAKFEEVGAKVEIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: FUT11_XENTR
Sequence: MSAGCTQLVWGGRLHWGASHLLSCLLALCALWVLAAAEPTEGGSANVQGVGEAALYQGRGQHRVPSEDNVAVLSDQWEPSSFQPSSAFSGTDLGTMVADSYRGPGNSDRRSNKELPILLWWSENLFPHFPGDAERIDCPLSSCMVTKNKSVKLHKRTKSIIFYGTDFRAYEAPLPRLPHQTWALFHEESPMNNYVLSHLPGIRLFNYTATFSRESDYPLTLQWLPTIGYLHNPALSMAEKNRWRKNGYAPVLYMQSHCDVPSDRDRYVKELMKHLEIDSYGQCMKNREHPNKRLEDTSTATTEDPEFMAFTARYKFHLAMENAICADYMTEKLWRPMHLGAIPIYRGSPSVRDWMPNNHSIIMIDDFASPKELAEFIMTLDSDDEQYLKYLEYKKPGGTTNTFLLSSMEKREWGVNDMTAPNYLNGFECFVCDKENSRIKAEKTYKKSQQGGAAPEPHIADFNHMGCPMPTPGFGSAQEIPESDSWKQMWLQDYWQSFDQGEALTAMIQRNETNQDRFWDYMHETYIKRSMNH
What is the function of this protein?
Probable fucosyltransferase.
What are the official names of this protein?
Alpha-(1,3)-fucosyltransferase 11, Fucosyltransferase XI, Fuc-TXI, FucT-XI, Galactoside 3-L-fucosyltransferase 11, Fucosyltransferase 11.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 10 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Protein: 5056R_ASFP4
Sequence: MFSLQDLCRKNIFFLPNDFSKHTLQWLGLYWKEHGSVHRAEKDSIMIQNELVLSINDALLLAGEEGDTDVVQLLLLWEGNLHYAIIGALKTEKYSLVCEYHSQIQDWHVLLPLIQDPETFEKCHDLSLECDFICLLQHAVKCDMLSILVKYKEDLLNVRIRHRIQSLFVLACENRRFEIIEWIGQNLPIPEPEAIFSIAIVTKDIELFSLGYKLIFDYMQRQGTFQLTNMVRMLLLNRYIGMAIEKGLLPFIVETLKYGGSVNRALSYAVIDNKRKIIDYLVRHENIPRGTIERLLHLAVKKQSSRKTLNLLLSYINYKVKNVKKLVEHVVDHNSTLVLKILLEKKENLVDAVLTRLVKHSTYFRVREFIQEFSISPEKFIKIAVREQKNVLIEAISEDIWENPTERITYLKQIVHTIKYESGRRFLIDIIHSIYQSYSLKHEDILKLAIFYVKYNAITHFKDLCKYLWLNRGTESKKLFLECLEIADEKEFPDIKSIVSEYINYLFTAGAITKEEII
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 505-6R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 505 family.
Protein: FIP1_KLULA
Sequence: MSSEDEDDKFLYSDEEDSNVVAKQEGPALKRQKVEETPKILAHDVPEGNTNEVESEASNQDSSSDEDDSSDSDSDVEIIIGTGNDTSKIDSGKSQISAITDTTPLGTADHAIAAVAGISDVVPVQEGSIPPEQQQQQQQTIDLNPDAQFDGKPIVQIDPEILKEKPWRQPGANISDYFNYGFNEQTWMEYLHRQEHLTKEYNPQKILMNLLALQQQGKLNDPGSGQPVQNTIQPPPPPMGLPPMFGGFPGFPFPGMMNNMQNQNVSSMNNMNNMNNMNNMNNINNNNNNNLNDKK
What is the function of this protein?
Pre-mRNA polyadenylation factor that directly interacts with poly(A) polymerase.
What are the official names of this protein?
Pre-mRNA polyadenylation factor FIP1.
What is the protein family that this protein belongs to?
Belongs to the FIP1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KEFB_ECOK1
Sequence: MEGSDFLLAGVLFLFAAVAAVPLASRLGIGAVLGYLLAGIAIGPWGLGFISDVDEILHFSELGVVFLMFIIGLELNPSKLWQLRRSIFGVGAAQVLLSAALLAGLLMLTHFSWQAAVVGGIGLAMSSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAVIPALALVPLLAGSADEHFDWMKIGMKVLAFVGMLIGGRYLLRPVFRFIAASGVREVFTAATLLLVLGSALFMDALGLSMALGTFIAGVLLAESEYRHELETAIDPFKGLLLGLFFISVGMSLNLGVLYTHLLWVVISVVVLVAVKILVLYLLARLYGVRSSERMQFAGVLSQGGEFAFVLFSTASSQRLFQGDQMALLLVTVTLSMMTTPLLMKLVDKWLSRQFNGPEEEDEKPWVNDDKPQVIVVGFGRFGQVIGRLLMANKMRITVLERDISAVNLMRKYGYKVYYGDATQVDLLRSAGAEAAESIVITCNEPEDTMKLVEICQQHFPHLHILARARGRVEAHELLQAGVTQFSRETFSSALELGRKTLVTLGMHPHQAQRAQLHFRRLDMRMLRELIPMHADTVQISRAREARRELEEIFQREMQQERRQLDGWDEFE
What is the function of this protein?
Pore-forming subunit of a potassium efflux system that confers protection against electrophiles.  Catalyzes K(+)/H(+) antiport.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system protein KefB, K(+)/H(+) antiporter.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ER10A_ASPFU
Sequence: MAIQTTTGLAARLVAKRATFPASRRNFSASRSALKEIQEAYILSGARTPTAKFNGSFVSVSAPELGAVAIKSAVSKSGVPVEKITDVYMGNVLQGAVGQAPARQASMFAGLSPTVESMTVNKVCASGLKAVALAAQNIQLGLAEAQVAGGMENMSRVPYYLPRSTQLPPFGEIKLQDGLIQDGLWDVYNQFHMGICAEKTAKKYEISREEQDQYAIQSYQRAQAAWKENKFAEEIAPVTVKGKKGETVVERDEGYENLRIDKMATLKPAFLRDGTGTVTAGNASTMNDGASALVLGSKAIAREFAQGNRALARIVSTADAAIDPVDFPVAPAKAVPIALERAGITKDQVAVWEFNEAFAAVIKANEKILGLQNARVNPLGGAISLGHALGSSGSRILVTLLHQLQPGEYGVAAICNGGGAATAMVVQKLDRVD
What is the function of this protein?
Mitochondrial acetyl-CoA acetyltransferase that catalyzes both the formation and degradation of acetoacetyl-CoA (PubMed:32005728).  Has no overlapping function with erg10B and seems not to be involved in ergosterol biosynthesis (PubMed:32005728).  Plays an important role in growth, morphogenesis and maintaining mitochondrial function including the response to oxidative stresses (PubMed:32005728).
What are the official names of this protein?
Acetyl-CoA acetyltransferase erg10A, mitochondrial, Acetoacetyl-CoA thiolase erg10A, Ergosterol biosynthesis protein 10A.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PYRD_ECOBW
Sequence: MYYPFVRKALFQLDPERAHEFTFQQLRRITGTPFEALVRQKVPAKPVNCMGLTFKNPLGLAAGLDKDGECIDALGAMGFGSIEIGTVTPRPQPGNDKPRLFRLVDAEGLINRMGFNNLGVDNLVENVKKAHYDGVLGINIGKNKDTPVEQGKDDYLICMEKIYAYAGYIAINISSPNTPGLRTLQYGEALDDLLTAIKNKQNDLQAMHHKYVPIAVKIAPDLSEEELIQVADSLVRHNIDGVIATNTTLDRSLVQGMKNCDQTGGLSGRPLQLKSTEIIRRLSLELNGRLPIIGVGGIDSVIAAREKIAAGASLVQIYSGFIFKGPPLIKEIVTHI
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SEC16_ASPFU
Sequence: MAQPEGVLAWNPAFRPEDNDSVATDLARLALDSGKEVSETTDVDTHVSPPAEEFTDENGSIESKTAISADTSDQGAPDLVDSNTPAADNGSKPDTEEPDKPSRDESIFMQTDKSRAVEDVTENVPTENGNVDITSGLEEHVAEEPHYEGPEKSTGLAGRNDAQDLFEGNDTAWMDEAEGEVNGATVNGEASGTRPGFWDSLGDNERDNEDDFFNQLKTQTKPIYSPPETEARFEEGIPLLGQGAAPQNNHAHKGESQVDDVFGDDEDDESGFFSEIQKRTSAEGPPPITRKSTSQVIDSINAVSDSMFSKQLPAAAELNNSLAVPTADGEIKNSPSEEDLAARWQAELSDDADETMPTEDDLAARWQAELDDDDDDLLLDDDTTNAQRPPEAANIDHMNDTSMLQSPFGTPENLARPKVQPVSYTPHQPSTSDLLSGIPAQNTAAQPTNASMSSYFSAQAPPNPVTTRAESFAERSKEGYKSPYDIPEDLARPRRAVANSRTVVAQPGTVPKPPPRSSSIPAPPLKASTVSPAPLGTSSTAPTAPQKNFFEELPLPPPRPKSRPASSGRYTPNAPVSAPSLPQSIPPPANQYSNVPGAPQSNIGPPDPPQLQQPERLDPYSNLLAPNVPSAPAVPSTASRYSPRPPGVQAGVKPPPSPRYSPAPPQSTNAVAAAPRNRYASQPASISGQGAALQFQPRTSSPLAYHEKIHYEDQGQSEERPQLQSTASPPPLNHSHPSEQPVSSENKGPSGVDVLENVPPLSTRPQSPPKNPYAPSAYTNEFANRVAPVSTGPPIAGMTGVLNSSTEESPFVPPRRSQTQSPSQTLSPRLSVPSLDPFQRPASVHGSTSPTRTVNPYAPAPVPTHNRAPSQVLEFIPPTDGQQLDSLERWKGAPIFKFGFGGAVISCFPKHIPRYSAGQAAPMIKSCPGEVRISQLNDWLPAAEGIVQHPGPLKGKSKKKDLVAWLSSKIAAFENADIPDFDRLSPDASKLREEKTLLWKVIRVLVENDGVLEGSVEAQKSLRNLLFPNLQDSGPNQSLGDVFTPSATLQPLNAPSQPDAVDSRSVDLLRDTLVLGEREKAVWAAVDKRLWGHAMIIASRMDRSVWQQVVQEFVRREVRSATSRTESLAAFYEILAGNIEESIDELVPPSARAGLQMISKVDGHGPAKNSLDGLDSWRETVGLVLSNRSPDDQRALVALGRLLLSYNRTEAAHICFILSRVAVFGGLDDPQANIVLLGVDHQRLSSCAALYNDDSILLTEAYEFATSVLAGSSVSTLPHLLAFKLIHAWSLAERGRKSEAQQYCDAIAAALKATTKPSGYHNQHLFFGVDELSARLRETTSDGGSSWISRPSMEKVSGSMWAKFNSFVAGDDSDAASTGSVKAEEIGPFARVSGTPTISRSPSVSDIYGSYPVAAAQPLPATGPSRYQPVSQYAPSASPEQLRGRSSMDSQRSASFGYPLGQRRGSQEPSTPVDTNMFHGMPMYGSPPVAGYQSTPPQSSYMPLAPVAEDSASGAQQESFSAHSQVSDNAPSHRSSTYAPEPFGHPFDTQAVSTTSQPDQGGYMPPTSSGAYEPPSFESNTESADGAQDESTEEDKPKKKSIMDEDDDEDLAARAAAIQKAERARRDREADEAFRKAAEADAKKPPPATGKKGWFSGWFGGKKDDNSGGGPIRAKLGEENSFYYDTELKKWVNKKDPGSAAPTRGTPPPPKGSAPPSRSMSGSGGPPPAMATPPPTGASGSRPSSSAGAPTSVSASPAPPSLGAPPPAIPRSVSTGAVLPTPPSSSAGAPPRPATSLSNASSIDDLLGAPQARKGPAARGKKKGRYVDVMAK
What is the function of this protein?
Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules.  Also involved in autophagy (By similarity).
What are the official names of this protein?
COPII coat assembly protein sec16, Protein transport protein sec16.
What is the protein family that this protein belongs to?
Belongs to the SEC16 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL27_CHLPD
Sequence: MAHKKGGGSTKNGRDSNPKYLGVKAAGGSTVSAGTIIVRQRGTVIKPGNNTGIGRDHTIFSLVDGVVTFRNGRNDKKRVEIVPS
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: LPXD_POLSJ
Sequence: MTLRLADIVQSLAPTVQAELVGNPDVQIERLSTLDAAGPHDLSFLSHPKYLAKLAQSAAACVVVAPAAREAAVSRGACIVVDDPYHYFALITQLWKYRHVLQAAPHIHPSAFIDPAATLAPGVSVGAFACISAGTVIGAGARIAEHCVIGRDAHVGAESRLSARVTVADGCYIGERCIVHPGAVIGADGFGFAPHQGQWIKIEQLGAVKIGNDVEIGANTCIDRGALQDTVLEDGVKLDNLVQIGHNVRIGKHTAMAGCAGVAGSATIGAHCTVGGGAIVLGHLSLADHVHISAASVVTRSILKPGHYTGLFPIDDNTAWEKNAATLKQLHVLRERLKQAEKSLSNIQEKS
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: RUVC_FRAP2
Sequence: MVILGIDPGSRITGFGIIKIHDNKLYYVASGCIRITETGTARRLKQIADGITEVVNTYAPTESAIEQIFMFQNPGAALKLGQARGVAMCTLAINNLEVSEYSAKQIKQAVVGTGGAAKSQVQHMVQSILGLSKKPPEDAADALAIAICHYHSSKSLARIAGASRVSQKRIR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: Y994_AERHH
Sequence: MIIPWQELDADTLNNLLEHFVLQEGTEYGEHDVSLADKVADVRTQLQQGLAVIVYSELHESVNIVPKATLDRAQVDDIPE
What are the official names of this protein?
UPF0270 protein AHA_0994.
What is the protein family that this protein belongs to?
Belongs to the UPF0270 family.
Protein: FMT_SHEDO
Sequence: MKPLNIIFAGTPDFAARHLQALLDSEHNVIAVYSQPDRPAGRGKKLSASPVKELALSHDIPVFQPASLRAVEAQAELATLNADIMVVVAYGLILPQIVLDTPRLGCINVHGSILPRWRGAAPIQRALWAGDTETGVTIMQMDLGLDTGDMLLKTSLPIEDADTSASLYEKLAVQGPQALLEALDGLNAGKLKGEPQDPALANYAEKLSKEEARLDWNKSAKQLWQEIRAFNPWPVSYFEYQDSTIKVWQASYNPQPNSALAGSIIKADKHSIEVATAEGSLQLEIIQLPNKKPLAVADILNSRADWFAQGLSLLPEASS
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: LDH1_STAAB
Sequence: MNKFKGNKVVLIGNGAVGSSYAFSLVNQSIVDELVIIDLDTEKVRGDVMDLKHATPYSPTTVRVKAGEYSDCHDADLVVICAGAAQKPGETRLDLVSKNLKIFKSIVGEVMASKFDGIFLVATNPVDILVYATWKFSGLPKERVIGSGTILDSARFRLLLSEAFDVAPRSVDAQIIGEHGDTELPVWSHANIAGQPLKTLLEQRPEGKAQIEQIFVQTRDAAYDIIQAKGATYYGVAMGLARITEAIFRNEDAVLTVSALLEGEYDEEDVYIGVPAVINRNGIRNVVEIPLNDEEQSKFAHSAKTLKDIMAEAEELK
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate (Potential).  Appears to be the primary factor that allows S. aureus growth during nitrosative stress in both aerobically and anaerobically cultured cells (By similarity).
What are the official names of this protein?
L-lactate dehydrogenase 1, L-LDH 1.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAOP2_ARATH
Sequence: MGSTPTDLPGEDVADNRSGVGGGISDVYGEDSATLDQLVTPWVTSVASGYTLMRDPRYNKGLAFTDKERDAHYLTGLLPPVILSQDVQERKVMHNLRQYTVPLQRYMALMDLQERNERLFYKLLIDNVEELLPVVYTPTVGEACQKYGSIFRKPQGLYISLNEKGKILEVLKNWPQRGIQVIVVTDGERILGLGDLGCQGMGIPVGKLSLYTALGGIRPSACLPITIDVGTNNEKLLNDEFYIGLKQRRATGQEYAEFLHEFMCAVKQNYGEKVLVQFEDFANHNAFDLLSKYSDSHLVFNDDIQGTASVVLAGLIAAQKVLGKKLADHTFLFLGAGEAGTGIAELIALKISKETGAPITETRKKIWLVDSKGLIVSSRKESLQHFKQPWAHEHKPVKDLIGAVNAIKPTVLIGTSGVGQTFTKEVVEAMATNNEKPLILALSNPTSQAECTAEQAYTWTKGRAIFGSGSPFDPVVYDGKTYLPGQANNCYIFPGLGLGLIMSGAIRVRDDMLLAASEALAAQVTEEHYANGLIYPPFSNIREISANIAACVAAKTYDLGLASNLPRAKDLVKFAESSMYSPVYRNYR
What are the official names of this protein?
NADP-dependent malic enzyme 2, AtNADP-ME2, NADP-malic enzyme 2.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFRB_GEOSL
Sequence: MAQVVFSSWGRTIVDNRKGGEAQDVSFRLPTTLDGERQIAAFMGWDGIILYDLKVDVPAMAAEYMKRVQTQYCCGKCTPGKKGTKVLADVLAAIIEGRATEADLDTIDDLADLLTNCKCTLCQSSTIPVLDAVKHFREDFLAYITGIRKPANVHRFIDKYTAPCMDRCPAHIDIPAYIEAIKEYRFDESLDIIRDNMPLPSVCGRVCPHPCETHCRRKNVDDSVNIMVLKRSASDYEWMHNAAPPMQPKPQKNKKVAIVGAGPAGLACAYYLALEGYPCTIYEALPEGYGGGMIAVGIPPYRQPRHLLQRDIDIISSMGVDIIYDTRIGKDISLEELKQKFDAVFLAPGAHRSKPMGVEGEDKGYKGFLKGGIDFLREAYMGRPTGMGKKVVVVGGGNTAIDCVRVALREGAEESTLLYRRSRKEMPADVWEVDGADEEGVRFEFQVLPTRVLVDENEQVTGVECVRMALGEPDASGRRRPEPVPGSEFVVECDTVIPAIGQDPDLSFIPDNLGIDITKWNTVVTKYVPLKDAAGKDLKDGMGNPLARVLITDLEGVFAGGDAEIGPLTVVACIGNAHRAARVIQRWLEEGKAYLTEDELMEDILTNMPVYDKNEKVPWLDSRERAHQAEVHGQERASKGNYQEVELGFVDTQAVEEAERCLRCYRVAMAAI
What is the function of this protein?
May catalyze the NADPH oxidation in the SfrAB NADPH-Fe(3+) oxidoreductase enzymatic complex.  Probably involved in acetate metabolism and not in the reduction of Fe(3+) chelates.  May serve as a major route for NADP regeneration.
What are the official names of this protein?
NADPH-Fe(3+) oxidoreductase subunit beta, Soluble Fe(3+) reductase beta subunit.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: IBMP_CAMVW
Sequence: MENIEKLLMQEKILMLELDLVRAKISLARANGSSQQGDLPLHRETPVKEEAVHSALATFTPSQVKAIPEQTAPGKESTNPLMASILPKDMNPVQTGMRLTVPGDFLRPHQGIPIPRKSELSSTVAPLRAESGIQHPHINYYVVYNGPHAGIYDDWGCTKAATNGVPGVAHKKFATITEARAAADAYTTSQQTDRLNFIPKGEAQLKPKSFAKALTSPPKQKAHWLTLGTKKPSSDPAPKEISFDPEITMDDFLYLYDLVRKFDGEGDDTMFTTDNEKISLFNFRKNANPQMVREAYAAGLIKTIYPSNNLQEIKYLPKKVKDAVKRFRTNCIKNTEKDIFLKIRSTIPVWTIQGLLHKPRQVIEIGVSKKLVPTESKAMESKIQIEDLTELAVKTGEQFIQSLLRLNDKKKIFVNMVEHDTLIYSKNIKETVSEDQRAIETFQQRVISGNLLGFHCPAICHFIVKIVEKEGGTYQCHHCDKGKAIVKDASADSGPKDGPPPTRSIVEKEDVPTTSSKQVD
What is the function of this protein?
Enhances the ribosomal termination-reinitiation event leading to the translation of major open reading frames on the polycistronic viral RNAs.
What are the official names of this protein?
Transactivator/viroplasmin protein, Tav, Inclusion body matrix protein.
What is the protein family that this protein belongs to?
Belongs to the caulimoviridae viroplasmin family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Found in cytoplasmic occlusion bodies.