PharMolix/UniProtQA huggingface dataset:
Protein: KHSE_BRUME
Sequence: MAVYTDINEIELGAFLRHYDIGTLTSYKGIAEGVENSNYLLHTSSGSFILTLYEKRTNREDLPFFLGLMQHLAKRGLECPQPVVRNDGAMIGQLAGRPAAIVTFLEGMWMRRPTVAHCEAVGEGLAHMHLAGADFPMRRRNGLTLPDWRPLWNLSRKCADTVERGLVAETEADLDFLEKNWPADLPQGVIHADLFPDNAFFLGDRLSGFIDFYFACTDILAYDVAVCLNAWCFEKDFSYNRTKGAALLRGYTSVRPLSEAEANALLVLARGAAVRFMLTRLYDWLTVPAGSFVVKKDPMEYVRRMRFHRQIESGAEYGLEMQGVAA
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the pseudomonas-type ThrB family.
Protein: GUAA_CALS4
Sequence: MGIKRETILILDFGGQYTQLIARRIREANVYCEIVPYDISPEEIKKIDPKGIVLSGGPASVYVKNAPKCDKEIFELGYPVLGICYGVQLMTELLGGKVAPAPVREYGKTEVVINNTIPLFKGIERDTIVWMSHTDQIELPPPDFKVVASTENCPIAAIANVEKKLYGVQFHPEVSHTHRGTEIIRNFLFEVCDCSADWTMDSLIEQTVKEVRAKVGNHKAVCALSGGVDSAVAAVLVDRAIHDQLVCIFVDTGLLRTNEGDMVIETFRKNYDMNIIRVDAKDRFLSRLKGVTDPEEKRKIIGNVFIEVFKEEAMKIGDVKFLVQGTLYPDVIESGHGISSTIKSHHNVGGLPEDIGFELIEPLRMLFKDEVRQVGKELGIPDEILYRQPFPGPGLAVRIVGEVTEEKLEILRLADSIVQREMKRFGWYNKVWQSFAILPGIKSVGVMGDERTYGYAIILRVVDSMDGMTADWTKLPYEILESISTSITNEVPGVNRVLYDITSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: 3L22A_AUSLA
Sequence: MKTLLLTLVVVTIVCLDLGDSLRCYMGPKTPRTCPPGENLCFTKTWCDPRCSLLGKLVKLGCAATCPIPKSYEDVTCCSTDNCNRFPKWERSRPRPRGLLSSIMDHP
What is the function of this protein?
Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission.
What are the official names of this protein?
Alpha-elapitoxin-Al2a, Alpha-EPTX-Al2a, Putative long neurotoxin.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Long-chain subfamily. Type II alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CWC21_SCHPO
Sequence: MSYNGIGLPTPRGSGTNGYVMRNLSHVKKYDKNTNLQSNRNAKALEKRVQDPSISEHECRRQIESKLLLYREQLLEEVSSQHSTDAAASDSNTNFGTENPKPPKAIIKDEQSQSKTKSLDEADVEILVQKYREQLLKELQLQKSTEKGKNFESILQPQKRKETRGFHSKNDDDGRLEERDDLRSSVDDDYYDYPRYSERKSLNSKRHVDNYNENRRRHYDSYSSYDELERRRSSNESYSRRSELPRRDYNRHDERERYSYHRRRERSNSPSYTKNESIPVVDRDSSPEGGEIV
What is the function of this protein?
Involved in pre-mRNA splicing.  May function at or prior to the first catalytic step of splicing at the catalytic center of the spliceosome.  May do so by stabilizing the catalytic center or the position of the RNA substrate (By similarity).
What are the official names of this protein?
Pre-mRNA-splicing factor cwf21, Complexed with cdc5 protein 21.
What is the protein family that this protein belongs to?
Belongs to the CWC21 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CATE_ALKPO
Sequence: MSNEREMQNKKDQQLESFRVEDEGKKLTTNQGLKVSEDEFSLKAGERGPTLMEDFHFREKMTHFDHERIPERIVHARGFAAHGEFQVYDSMKEFTKAKFLQDPSVKTPVFVRFSTVAGSKGSAETVRDARGFATKFYTEEGNYDLVGNNIPVFFIQDAIKFPDLVHALKPEPHNEIPQAQSAHDTFWDFIANNQESAHMVMWAMSDRSIPRSFRMMEGFGVHTFRFVNEEGKAHFVKFHWKPVLGIHSLVWDEAQKIAGKDPDFHRRDLWESIENGDYPEYELGVQLISEEDEFNFDFDVLDPTKIWPEEEVPVKIIGKMTLNRNVDNVFAETEQVAFHPGHVVPGIDFTNDPLLQGRLFSYTDTQLIRLGGPNFHELPINRPVCPFHNNQRDGYGRQTINKGQVSYHKNSLAANTPQPASEEEGGYAHYQEKVEGRKVRKRSESFKDHFSQAKLFWNSMSEVEKNHIIEAFSFELGKVQSKSVQQQVVEMFAHVTSDLAKPVAEAIGANLPQSEGSSVTKSSLALSQENTIKKPDTRKVGVIIDNGFNGDEVKQVLNELQSKGIQAEFISDKLGIKKCAGGSEIEIDHTFLTGESVLFDALYVVGGKEVDPSFKDDAVYFIKEAYAHFKPIGATHVGIKWLEEQEIVEKEGVVTGTDMNIFSQNLTGAVMEHRHWNR
What is the function of this protein?
Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase.
What is the protein family that this protein belongs to?
Belongs to the catalase family. HPII subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOSB_BACC4
Sequence: MLRGINHICFSVSNLENSIMFYEKVLEGELLVKGRKLAYFNICGVWIALNEETHISRNEIHQSYTHIAFSVEQEDFKCLIQRLEENDVHILQGRERDVRDCESIYFVDPDGHKFEFHSGTLQDRLNYYRDEKPHMTFY
What is the function of this protein?
Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin.  L-cysteine is probably the physiological thiol donor.
What are the official names of this protein?
Metallothiol transferase FosB, Fosfomycin resistance protein.
What is the protein family that this protein belongs to?
Belongs to the fosfomycin resistance protein family. FosB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTC_LEVBA
Sequence: MTKRDFIDTNTYTKEEIQYMIDLGIKIKESIKNGYYPPLLKNKTLGMIFEQSSTRTRTSAEAAMTELGGHAQYLAPGQIQLGGHETIEDTSQVLGRILDIIGARVERHHTVAEVGKFAKVPVVNFMSDYNHPTQELGDIITMTEHLPKGKKLSDCKIVFVGDATQVCVSTMFMATKMGMDFVQFGPKGFQIKPETLKIGQQNAKVSGGSVTITEDADEAFKDADFIYTDVWYGLYEAELSEEDRMKIFYPKYQVNAELVAKASDHVKFMHCLPATRGEEVTDEVIDSDYSIVWDEAENRKTAMRAIFVYLLNPELRKAQASQAVADKYDAEFSLMLRNAVDDQRNAD
What is the function of this protein?
Catalyzes the phosphorolysis of N-carbamoylputrescine to form carbamoyl phosphate and putrescine.  Is involved in the degradation pathway of the polyamine agmatine.
What are the official names of this protein?
Putrescine carbamoyltransferase, PTC, PTCase, Putrescine transcarbamoylase, Putrescine transcarbamylase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. PTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_CLAMS
Sequence: MSDTTTGSDAADAAVPATTPADLEAASARVDELRAEIERHRDAYYGETGGTVSDAEYDALERELRAIEDAHPTLRSQDSPTQTVGGRAETTLFAPVTHAERMLSLDNVFSEEELAEWAAKVERDAGRGRVRYLSELKIDGLAINLRYEHGVLVTAATRGDGVVGEDVTQNVLTMGTVPERLAGSGHPPLVEVRGEIFFPVAEFDELNARQLEVGERVFANPRNAAAGSLRQKEEGKSPARLELMHARIRRLRMLVHGIGAWPVRELERDAHVSAQSEVYGLLEAWGLPISTHFRVFDDIAEVAGFVRRQGADRAAVEHQIDGIVVKVDDLGLHEELGATSRAPRWATAYKYPPEEVNTTLLDIVVSVGRTGRATPFAVMEKVEVAGSEVRQATLHNQQVVKAKGVLIGDTVVLRKAGDVIPEVLGPVVELRTGKEHEFVMPTLCPECQTPLKPAKEGDIDLRCPNARSCPAQVRGRVEHVASRGALDIEGLGEVAAAALTQPLEPEDPPLETEAGLFELTMADLVPITVVVRDAETGMVKVDEKTGEAKRVTPFRRKRVLKRDGAFDPAEPWGDEASVPSKSAEVLLENLEKAKTQDLWRILVALSIRHVGPVAARALAGWFGSLDVIRAASREELAAVDGVGGIIADALLDWFEVDWHREIVARWEKAGVVTAVPGHPGPGAAAAAGGVLAGLAVVATGSLEGYTREGALEAIMAAGGKAGSSVSKKTHYVAAGPGAGSKLGKAEALGVRIIDAAEFRLLVEQGPDAIALPEADPVPDAAETAPDGGSAEDATAATAGAAEAATAEAKPKRARKRKAPAAAAAAPPTDVEAGTAVHAEPDGPAETP
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: NU1C_SYNSC
Sequence: MVSPGLDLELSFSQALQGFGFSPEVARLLWLPLPMLLVLVAAVVGVLVSVWLERKISAAVQQRIGPEYAGALGVLQPLADGLKLLVKEDIIPARADSLLFTLGPVLVVVPVIISWLIIPFGQNLLISNVGVGIFLWISFSSIQPIGLLMSGYASNNKYSLLGGLRAAAQSISYEIPLALAVLAIVMMTNSLSTVDIVGQQTGAGILSWNIWRQPVGFLIFWICALAECERLPFDLPEAEEELVAGYQTEYAGMKFALFYLAGYINLVLSAVLVSVLYLGGWGFPIPVEWLAGWLNQPIDAPLVQVITGTVGIVMTVLKAYLLVFVAILLRWTTPRVRIDQLLDLGWKFLLPLSLVNLLVTAALKLAFPVAFGG
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 1, NAD(P)H dehydrogenase I subunit 1, NDH-1 subunit 1, NDH-A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: HYDL_STRCO
Sequence: MNERADRSGGAAPGGDRTHRVPVLVVGGSLVGLSTSVFLGRLGVRHTLVERHAGTSIHPRGRGNNVRTMEIFRVAGTEPDIRRAAATLADNHGILQAPTLAGDAGEWLFKQIDPGGGLARFSPSSWCLCSQNDLEPELLTHATNLGGDLRFGTELLSFEADTEGVTAIVKSRETGEHTTIRADYLVAADGPRSPVREQLGIGQSGPGDLFHNVSITFRSRRLADVVGDRRFIVCYLTDENADGALLPVDNRENWVFHAPWHPEQGETVEDFTDERCAAHIRRAIGDPDLDVEITGKAPWHAAQRVARSYRSGRVLLAGDSAHEMSPTGAFGSNTGIQDAHNLAWKLAAVLEGWAGEALLDTYDTERRPVAEATSARAAHRSVEHSHPGFAPPPVAGGGGPGAGTPGGAGRGTGGPGGPGGPGGLGGPGGPGGTGGPGGPGGPGGPDGPRGAGGAPGGGPGGGPGGGGPQRGILNVALGYRYPRGAVVGADPATPVVPEGLDLTGAPGSRAPHLWVRRGQDRLSTLDLYEDSLVLLSDAAQPTGWHEAAAGVAAGMRVPLKSYRVGGSPGADLNPDDEETDWARAHGVTRGGAVLVRPDGFVAWRSPGPAPDPESMLRQVVGTVLARS
What is the function of this protein?
Involved in developmentally regulated synthesis of a compound biosynthetically related to polyketide antibiotics which is essential for spore color in Streptococcus coelicolor.
What are the official names of this protein?
Putative polyketide hydroxylase, WhiE ORF VIII.
What is the protein family that this protein belongs to?
Belongs to the PheA/TfdB FAD monooxygenase family.
Protein: PACN1_HUMAN
Sequence: MSSSYDEASLAPEETTDSFWEVGNYKRTVKRIDDGHRLCNDLMNCVQERAKIEKAYGQQLTDWAKRWRQLIEKGPQYGSLERAWGAIMTEADKVSELHQEVKNNLLNEDLEKVKNWQKDAYHKQIMGGFKETKEAEDGFRKAQKPWAKKMKELEAAKKAYHLACKEEKLAMTREMNSKTEQSVTPEQQKKLQDKVDKCKQDVQKTQEKYEKVLEDVGKTTPQYMENMEQVFEQCQQFEEKRLVFLKEVLLDIKRHLNLAENSSYIHVYRELEQAIRGADAQEDLRWFRSTSGPGMPMNWPQFEEWNPDLPHTTTKKEKQPKKAEGVALTNATGAVESTSQAGDRGSVSSYDRGQPYATEWSDDESGNPFGGSETNGGANPFEDDSKGVRVRALYDYDGQEQDELSFKAGDELTKLGEEDEQGWCRGRLDSGQLGLYPANYVEAI
What is the function of this protein?
Plays a role in the reorganization of the microtubule cytoskeleton via its interaction with MAPT; this decreases microtubule stability and inhibits MAPT-induced microtubule polymerization.  Plays a role in cellular transport processes by recruiting DNM1, DNM2 and DNM3 to membranes.  Plays a role in the reorganization of the actin cytoskeleton and in neuron morphogenesis via its interaction with COBL and WASL, and by recruiting COBL to the cell cortex.  Plays a role in the regulation of neurite formation, neurite branching and the regulation of neurite length.  Required for normal synaptic vesicle endocytosis; this process retrieves previously released neurotransmitters to accommodate multiple cycles of neurotransmission.  Required for normal excitatory and inhibitory synaptic transmission (By similarity).  Binds to membranes via its F-BAR domain and mediates membrane tubulation.
What are the official names of this protein?
Protein kinase C and casein kinase substrate in neurons protein 1, Syndapin-1.
What is the protein family that this protein belongs to?
Belongs to the PACSIN family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection. Synapse, synaptosome. Cell projection, ruffle membrane. Membrane; Peripheral membrane protein. Cytoplasmic vesicle membrane; Peripheral membrane protein. Synapse. Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Colocalizes with MAPT in axons. In primary neuronal cultures, present at a high level in presynaptic nerve terminals and in the cell body. Colocalizes with DNM1 at vesicular structures in the cell body and neurites (By similarity). Associates with membranes via its F-BAR domain.
Protein: APT_HAEDU
Sequence: MNQLDLIKSSIKSIPNYPKVGIIFRDITSLLENPTAFKASIDAIVAEFKNKGITKVVGTESRGFIFGAPVALALGLPFVLVRKPHKLPRAVISQSYALEYGEDTLEMHLDSINQDDNVLVVDDLLATGGTIDATAKLIRQLGGQVKNAAFVIGLPDLGGKARLEQIGIKSFTLVEFDGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPR20_ARATH
Sequence: MRRRLSSVLINNQCIASQRHYHTSRPEKPTKKASSHEPTHKFTRKPWEEVPFLTDLKEIEDPEEALSLFHQYQEMGFRHDYPSYSSLIYKLAKSRNFDAVDQILRLVRYRNVRCRESLFMGLIQHYGKAGSVDKAIDVFHKITSFDCVRTIQSLNTLINVLVDNGELEKAKSFFDGAKDMRLRPNSVSFNILIKGFLDKCDWEAACKVFDEMLEMEVQPSVVTYNSLIGFLCRNDDMGKAKSLLEDMIKKRIRPNAVTFGLLMKGLCCKGEYNEAKKLMFDMEYRGCKPGLVNYGILMSDLGKRGRIDEAKLLLGEMKKRRIKPDVVIYNILVNHLCTECRVPEAYRVLTEMQMKGCKPNAATYRMMIDGFCRIEDFDSGLNVLNAMLASRHCPTPATFVCMVAGLIKGGNLDHACFVLEVMGKKNLSFGSGAWQNLLSDLCIKDGGVYCEALSEVISI
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At1g07740, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SYP_FRATO
Sequence: MKATQTLIATTKELPKEAVLISHQYMLKAGLIKKLASGIYTWMPLGLKVLQKIQNIVRDEMNKAGASELLLPSILPSELLQETHRWDKFGPELLKLHDRHNRDFCYGPTHEEPIVDMARDTIKSYKQLPLNLYQIQTKFRDEIRPRFGVMRAREFIMKDAYSFHENSQCLRNTYNTMYATYCNILDKIGLAYRPVKADTGAIGGDNSHEFQVLANAGEDIICYSNGSDYAANIELATYAKPDLSKRVNSQNTIEKIHTPNIKTIEKLCKEMSFDIKKTIKTMVIKDAGGNFFALVIRGDHELNETKINKLDQIIAPYTLATKEEIFSIFNANPGSLGIYNCPISIIADYSAIAITDLVCGANEDDYHFTNVNWDRDVTNYQIADIRNVVTGDISPDGKGTLELTNGIEVGHIFELEDVYSKPMNANIIGQDGKSKPMLMGCYGFGVSRVMAAAIEQSHDENGIIWPESIAPYQVAILPINYNKSDKVKEVADKLCQDLLGDGIDVLLDDRGARPGVMFADADLIGYSHHVVIGDRLLEQGLIEYKNRKTQEKQEITIAELIKLLK
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSH_ECO8A
Sequence: MSNVPAELKYSKEHEWLRKEADGTYTVGITEHAQELLGDMVFVDLPEVGATVSAGDDCAVAESVKAASDIYAPVSGEIVAVNDALSDSPELVNSEPYAGGWIFKIKASDESELESLLDATAYEALLEDE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: RS11_DESAL
Sequence: MAKRKVARKRDKKNIPSGVAHIQATFNNTIVTITDPSGAVVSWSSAGVVGFKGSRKSTPFAAQLAAEDAAKKAMEHGMRNVEVYVKGPGSGRESALRALQGAGLNVVMLRDVTPVPHNGCRPRKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: SRO9_YEAST
Sequence: MSAETAAANTATAPVPEVQEQESSKSKQVNLTPAPLPTSSPWKLAPTEIPVSTISIEDLDATRKKKNRTPTPKSSTATKWVPIKASITVSGTKRSGSKNGASNGNSNKSKNNKTAASSTSSSNANRKKKHHQHNAKKQQQMKKDGFESAVGEEDSKDATSQENGQSTQQQQPPHHRNHHHSHHHNSNGPQRRKFHNSNNAGMPQNQGFPPQFKPYQGRNARNNNNNRSKYHNHFHHNQQHPQQPMVKLQQQFYPVQPVLMAINNIARQIEYYFSEENLTVDNYLRSKLSKDGFAPLSLISKFYRVVNMSFGGDTNLILAALREIVANEAATVNVAEGTLAAKEGDNVTGEAKEPSPLDKYFVRSKSWSNWLPETFETEINIEKELVGDALDQFMISLPPVPQQEEESSTELASQEQETKEDSAPVAAGESESSL
What is the function of this protein?
May overlap in function with tropomyosin and may be involved in organization of actin filaments.  Acts as a multicopy suppressor of RHO3 mutation.  RNA-binding protein which may modulate mRNA translation.  Involved in heme regulation of HAP1, as a component of the high-molecular-weight complex (HMC).
What are the official names of this protein?
RNA-binding protein SRO9, Suppressor of RHO3 protein 9.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associates with translating ribosome.
Protein: GLYA_LACPL
Sequence: MNYQEQDPEVWAAISKEQARQQHNIELIASENIVSKGVRAAQGSVLTNKYSEGYPGHRFYGGNEYIDQVETLAIERAKKLFGAEYANVQPHSGSQANAAAYMALIQPGDRVMGMSLDAGGHLTHGSSVNFSGKLYDFQGYGLDPETAELNYDAILAQAQDFQPKLIVAGASAYSRLIDFKKFREIADQVGALLMVDMAHIAGLVAAGLHPNPVPYADVVTTTTHKTLRGPRGGMILAKEKYGKKINSAVFPGNQGGPLDHVIAGKAIALGEDLQPEFKVYAQHIIDNAKAMAKVFNDSDLVRVISGGTDNHLMTIDVTKSGLNGRQVQDLLDTVYITVNKEAIPNETLGAFKTSGIRLGTPAITTRGFDEADATKVAELILQALQAPTDQANLDDVKQQAMALTAKHPIDVD
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THMS3_MOUSE
Sequence: MEQTWDSYISSLNQNSLPRQVEVTQGRYSGSLENLSFSKGDIITVVDLEPVFVRAELKDGDQVLDVVTIPLRYEGNFQLMADPVSFETVADLTRSVRLPQSPVAPRSPPRFQNSIPISADNLPMKLRKGETLSLIGFQESRGRRLLQCKVLRKKPPLTVLLPMDCRGHFLECQDDRFYSIDTIVRWKMLAGRKRTVRVQARHHPKLLGPLVPEHFRGHLVLYPCFSVTANLLGETRVSIPSDLDISVTEIARLDRKPRTTMRQIYSMEESKFPVRVKIMNVVQSESKEYPKPLKRGQLLTILKTEEVKKFVASEISQGKKGKCFLVPYTYQGLVLRRGRYFYAVSDVAAAMKHGELCFQASQDYTSYLGSFASFRANECFLALKKSVVSAEIHGELHRVEVLKCLNIATKAHVKLPLFAVGKFLELFDGARPGTLQELCQVTRLPCHVRVTSPDPSMTVDPLYGTKELRIENVIIEQCLIAKDEPTLEDIISSADMYREWPETTFEIPIEKISCEVLVVEERSWIADVRKERCRPLQSIQEVTKESLAFSNCLVIRRPPPPVPKPRSLF
What are the official names of this protein?
Protein THEMIS3, Thymocyte-expressed molecule involved in selection protein 3.
What is the protein family that this protein belongs to?
Belongs to the themis family.
Protein: PSTB_MYCS2
Sequence: MAKRLDLKDVNIYYGAFHAVADVSLAVQPRSVTAFIGPSGCGKSTVLRTLNRMHEVIPGARVEGSVLLDGEDIYGPGVDPVGVRKTIGMVFQRPNPFPTMSIRDNVVAGLKLQGVRNKKTLDEVAERSLRGANLWNEVKDRLDKPGGGLSGGQQQRLCIARAIAVQPDVLLMDEPCSALDPISTLAIEDLIATLKLDYTIVIVTHNMQQAARVSDQTAFFNLEATGKPGRLIEIDDTEKIFSNPRQKATEDYISGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RS18_DEIDV
Sequence: MTQQSNSADRKPRGKGPKRPRKPKVDPFSIGELEITDYKDVKMLRRFVSDTGKILPRRRTGLSAKHQRRIAQTIKVARQLALLPYTEKLVRK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: FAR7_STRNA
Sequence: ARSDNFVRL
What is the function of this protein?
FMRFamides and FMRFamide-like peptides are neuropeptides.
What are the official names of this protein?
Extended FMRFamide-7, FMRFa-7.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRF amide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS10_GEODF
Sequence: MPSQKIRIRLKAYDHKLLDVSVGEIVDTAKRTGARVAGPIPLPTVVNKYCVLRGPHVDKKSREQFEIRTHKRLIDILEPTQQTVDALMKLDLSAGVDVEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RLMM_ECO24
Sequence: MNKVVLLCRPGFEKECAAEITDKAGQREIFGFARVKENAGYVIYECYQPDDGDKLIRELPFSSLIFARQWFVVGELLQHLPPEDRITPIVGMLQGVVEKGGELRVEVADTNESKELLKFCRKFTVPLRAALRDAGVLANYETPKRPVVHVFFIAPGCCYTGYSYSNNNSPFYMGIPRLKFPADAPSRSTLKLEEAFHVFIPADEWDERLANGMWAVDLGACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFKFRPTRSNISWMVCDMVEKPAKVAALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYIQAQLDEHGINAQIQARQLYHDREEVTVHVRRIWAAVGGRRDER
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YJAG_SALTI
Sequence: MLQNPIHLRLERLESWQHVTFMACLCERMYPNYAMFCKQTEFGDGQIYRRILDLIWETLTVKDAKVNFDSQLEKFEEAIPAADDYDLYGVYPAIDACVALSELMHSRLSGETLEHAIEVSKTSITTVAMLEMTQAGREMTDEELKTNPAVEQEWDIQWEIFRLLADCEERDIELIKGLRADLREAGESNIGINFQQ
What are the official names of this protein?
Uncharacterized protein YjaG.
What is the protein family that this protein belongs to?
To H.influenzae HI_0431.
Protein: VP2_POVSM
Sequence: MGALLAVLAEVVELASVTGLSVESFISGEAFATAELLEAHIANLVTVGGLTEAEALAATEVPAEAYAALTSLSSTFPQAFTAVAATELATTGTLTVGATVAAALYPYYYDYSTPVANLNRGLNPEMALQLWFPEIDYEFPGLMPFVRFINYIDPTQWATNLFETIGRYSWESAQRYGQNLIAHEVRSASRELATRTAQGFSEAVARYFENARWAVSTLPRSLYSGLQSYYEQLPSLNPMQVRDLHRRLGQPIPNRIALEEQAIKSAEYVQKVDPPGGANQRIAPDWLLPLILGLYGDISPSWESTLEDIEEEEDAPQKKKRKRTKKNTPRSA
What is the function of this protein?
Structural protein that resides within the core of the capsid surrounded by 72 VP1 pentamers.  Following virus endocytosis and trafficking to the endoplasmic reticulum, VP2 and VP3 form oligomers and integrate into the endoplasmic reticulum membrane.  Heterooligomer VP2-VP3 may create a viroporin for transporting the viral genome across the endoplasmic reticulum membrane to the cytoplasm.  Nuclear entry of the viral DNA involves the selective exposure and importin recognition of VP2 or VP3 nuclear localization signal (shared C-terminus).  Plays a role in virion assembly within the nucleus (By similarity).
What are the official names of this protein?
Minor capsid protein VP2, Minor structural protein VP2.
What is the protein family that this protein belongs to?
Belongs to the polyomaviruses capsid protein VP2 family.
What are the subcellular locations of this protein?
[Isoform VP2]: Virion. Host nucleus. Host endoplasmic reticulum. Host endoplasmic reticulum membrane. SUBCELLULAR LOCATION: [Isoform VP3]: Virion. Host nucleus. Host endoplasmic reticulum. Host endoplasmic reticulum membrane.
Protein: RIMM_FRATM
Sequence: MSQDFVEIAKIGATYKLNGELNLYPLANSIETLLSYGDWYIQLPATNVWQQLKGESVLKRADKVYIKLANINNADTAKKYVNALIGVPKRALPQLAEDEVYFKDLIGCSVKNINNDSFGVVVDIIETGANGVLVCKEDNSEYLIPYVKQYIVSEDLNSKKIVVDWEYDY
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.