PharMolix/UniProtQA huggingface dataset:
Protein: TAL_METM6
Sequence: MKFFLDTANVDKIKEFNALGLVDGVTTNPSLIKKEGRDFYEVIKEICSIVEGPVSAEVIALDAEGMVNEAKELVKIAKNVVIKIPMTKEGMKAVNILSKEGIKTNVTLIFSANQALLAAKAGATYVSPFVGRLDDIGQDGLLLISEIMQIFGAYGIETEVIVASVRHPIHVTESAKMGADIATIPFDVLDKLFNHSLTDIGIEKFLADWDAHMKR
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PR40A_MOUSE
Sequence: MRPGTGAERGGLMVSEMESQPPSRGPGDGERRLSGSNLCSSSWVSADGFLRRRPSMGHPGMHYAPMGMHPMGQRANMPPVPHGMMPQMMPPMGGPPMGQMPGMMSSVMSGMMMSHMSQASMQPALPPGVNSMDVAAGAASGAKSMWTEHKSPDGRTYYYNTETKQSTWEKPDDLKTPAEQLLSKCPWKEYKSDSGKPYYYNSQTKESRWAKPKELEDLEGYQNTIVAGGLITKSNLHAMIKAEESSKQEECTTASTAPVPTTEIPTTMSTMAAAEAAAAVVAAAAAAAAAANANTSTTPTNTVGSVPVAPEPEVTSIVATAVDNENTVTVSTEEQAQLANTTAIQDLSGDISSNTGEEPAKQETVSDFTPKKEEEESQPAKKTYTWNTKEEAKQAFKELLKEKRVPSNASWEQAMKMIINDPRYSALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTSTTRYKKAEQMFGEMEVWNAISERDRLEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILDNMANVTYSTTWSEAQQYLMDNPTFAEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKTLLRERRRQRKNRESFQIFLDELHEHGQLHSMSSWMELYPTISSDIRFTNMLGQPGSTALDLFKFYVEDLKARYHDEKKIIKDILKDKGFVVEVNTTFEDFVAIISSTKRSTTLDAGNIKLAFNSLLEKAEAREREREKEEARKMKRKESAFKSMLKQATPPIELDAVWEDIRERFVKEPAFEDITLESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSESDDDDSHSKKKRQRSESHSASERSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDTEREKDKKEKDRDSEKDRSRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGELEKRRRTLLEQLDDDQ
What is the function of this protein?
Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function.  Plays a role in the regulation of cell morphology and cytoskeletal organization.  Required in the control of cell shape and migration.  May play a role in cytokinesis.  May be involved in pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-processing factor 40 homolog A, Formin-binding protein 11, FBP-11, Formin-binding protein 3.
What is the protein family that this protein belongs to?
Belongs to the PRPF40 family.
What are the subcellular locations of this protein?
Nucleus speckle. Nucleus matrix. Note=Colocalizes with AKAP8L in the nuclear matrix.
Protein: SC4AA_TAKRU
Sequence: MATILPPPGTALFRHFTRQSLATIERLKEETLIAPKAGAHEEEEPPTPNPDLEAGKSLPMIFGDPPSELLGTPLEDIDPFYKAQKTFVVVTKGNTIYRFNAEPACYILSPFSLVRRGAIKILIHSLFSTLIMITILSNCVFMTMSNPPAWSKTVEYVFTGIYTFEATVKVLSRGFCVGPFTFLRDPWNWLDFMVISMAYITEFVDLGNVSALRTFRVLRALKTITVIPGLKTIVAALIQSVKKMVDVMILTVFALAVFALVGLQLFMGNLRHKCIRWPIANETASELFNGTVFNDTLSYNDTTWLNDTLDSNSTFDFTEYIENAENQYFLEGSKDALLCGNSTDAGKCPEGYLCMKAGRNPNYGYTSFDSFGWAFLALFRLMTQDNWESLFQLTLRAAGQTYMLFFVVVIFLGSFYLINLILAVVAMAYDEQNQASQQEAKEKEEEFQRLLEQLKNQEQAQVLGSRASLTSKKSVSLTGSDVADDEQSLENNEALKDCNGRPIPRLIIRAPTMKESAADYELREKEESSVHSVLHLDEPGLRERSASVATAAASVATAAASVATAAAMEELEEAQRPCPPIWYRFADIFLKWNCCEKWVVFKKWVHFVVMDPFVDLAITICIVLNTLFMAMEHYPMTEEFDYMLSVGNLVFTGIFAAEMFFKLIAMDPYYYFQVGWNIFDSIIVTLSLVELGLANVQGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKDCVCKISSDCELPRWHMNDFFHSFLIVFRILCGEWIETMWDCMEVAGAGMCLVVFMMVMVIGNLVVLNLFLALLLSSFSGDNLSVGDDDGELNNLQIAIGRITRGGNWLKAFLIGTVQRVLGREPQKPAEEDPADEGEGKTEGMEMNHLDGFKLADGIANCLVGGQPSGVTLDGESSITVPIALGESDSENPSEDDDDQEDDVDSEVTCEENEHHSDGVEDEFGVLQHVKLMGALTDGDSSVCSTVDYQPPEPEVQEEEEEEPDLVEPEACFTDNCVKRWPCLNVDISQGKGKKWWNLRKTCFTIVEHDWFETFIIFMILLSSGALAFEDIYIERRRTVKIVLEFADKVFTFIFVIEMLLKWVAYGFKTYFTNAWCWLDFFIVDISLISLSANLMGFSDLGPIKSLRTLRALRPLRALSRFEGMRVVVNALIGAIPSIFNVLLVCLIFWLIFSIMGVNLFAGKFYRCINTTTAELFPISVVNNKSDCVALQEATQEARWVNVKVNYDNVAKGYLSLLQIATFKGWMDIMYPAVDSREVEEQPSYEINLYMYIYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKLGDKDIFMTEEQKKYYEAMKKLGSKKPQKPIPRPANLIQGLVFDFISQQFFDIFIMVLICLNMVTMMVETDDQSPAKEDFLFKVNVAFIVVFTGECTLKLFALRHYFFTNGWNIFDFIVVILSIAGTMLSDIIEKYFVSPTLFRVIRLARIGRILRLIKGARGIRTLLFALMMSLPALFNIGLLLFLIMFIFSIFGMSNFAYVKKEAGINDMFNFETFGSSIICLFQITTSAGWDTLLLPMLNKEPPDCDPAFENPGTDVKGNCGNPMMGMVFFCSYIIISFLVVVNMYIAIILENFNVAQEESGDVLCEEDFEMFNETWEKFDTGGTQFIEYSQLSDFCDALQEPLRVAKPNRQRLIEMDLPLVIGDRIHCVDVLLAVTQEVLGDTIEMVAMRESIEAKFNLNNPTSASYAPITTTVRQKEEDMAAVVIQRAYRNHLHKRGIHHAAYIQRSKTGRKAASEDAPEKEGLLAKKMGALYGSDADLADEVEGLRRRPDPQTRCSGARCSPEPPEPNIILVPVEITNELLLHSAPSQQSSPTQTILRETNV
What is the function of this protein?
Pore-forming subunit of a voltage-gated sodium channel complex through which Na(+) ions pass in accordance with their electrochemical gradient.  Alternates between resting, activated and inactivated states.  Required for normal muscle fiber excitability, normal muscle contraction and relaxation cycles.
What are the official names of this protein?
Sodium channel protein type 4 subunit alpha A, Voltage-gated sodium channel subunit alpha Nav1.4a.
What is the protein family that this protein belongs to?
Belongs to the sodium channel (TC 1.A.1.10) family. Nav1.4/SCN4A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NUAK2_HUMAN
Sequence: MESLVFARRSGPTPSAAELARPLAEGLIKSPKPLMKKQAVKRHHHKHNLRHRYEFLETLGKGTYGKVKKARESSGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRVVHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPKPSDACGLIRWLLMVNPTRRATLEDVASHWWVNWGYATRVGEQEAPHEGGHPGSDSARASMADWLRRSSRPLLENGAKVCSFFKQHAPGGGSTTPGLERQHSLKKSRKENDMAQSLHSDTADDTAHRPGKSNLKLPKGILKKKVSASAEGVQEDPPELSPIPASPGQAAPLLPKKGILKKPRQRESGYYSSPEPSESGELLDAGDVFVSGDPKEQKPPQASGLLLHRKGILKLNGKFSQTALELAAPTTFGSLDELAPPRPLARASRPSGAVSEDSILSSESFDQLDLPERLPEPPLRGCVSVDNLTGLEEPPSEGPGSCLRRWRQDPLGDSCFSLTDCQEVTATYRQALRVCSKLT
What is the function of this protein?
Stress-activated kinase involved in tolerance to glucose starvation.  Induces cell-cell detachment by increasing F-actin conversion to G-actin.  Expression is induced by CD95 or TNF-alpha, via NF-kappa-B.  Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells.  Phosphorylates LATS1 and LATS2.  Plays a key role in neural tube closure during embryonic development through LATS2 phosphorylation and regulation of the nuclear localization of YAP1 a critical downstream regulatory target in the Hippo signaling pathway (PubMed:32845958).
What are the official names of this protein?
NUAK family SNF1-like kinase 2, Omphalocele kinase 2, SNF1/AMP kinase-related kinase, SNARK.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
Protein: PIHD2_MOUSE
Sequence: MTVSSKGLLTHISQFWNMLDDLAENDPERYRNFIQQELKDGKQLCVNPEPQLCIQTKILKPNEKVLFINLCQWERIPAPQSATRPVPVSVGRPEDSAEASDAYTIIDVAYNPGVLQAAEKDQGIKDQLIRMAMLCIEERLQFTLAHSYHLTSFRLKGSIQRMKESLMGIKTDFPDLKAMTRTENTLARIRSSTVSEPNHLPEVLLTKKQASAKGRCLIEEISSSEIQVEVKKPAYELKVVKDRNEKPLKIELKVELPGIKSVSLCELSVSEVDILIEVSEMYRLCLNLPESINTEMTTAKFVKNKSALIITMPLA
What are the official names of this protein?
PIH1 domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the PIH1 family.
Protein: NADK_LACE2
Sequence: MKYFYIVTNRFKDPDGVNTRKIAHFLRSKGAECVCQIEQEKAFNKTGSYSDVRLVPNNTECVIVLGGDGTLIQASRELSEKDIPFIGVNIGTLGYLTDTDMSSFEETLESLLRDDYEIDRRMMLDGCIYRGEERIFSDMALNDVVINRNGALRIIDFDIYVNGEYLNTYSADGVIVSTATGSTAYSLSAGGPIIQPTARLIMVTPICPHSLNQRSIIFAADDEIMIEMKDNKSSSGRMTGSLKNDSARVATFDGESFCEVVTGDRIVITQSERISRFVKTSRISFLERIRNKM
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL371_ARATH
Sequence: MGKGTGSFGKRRNKSHTLCVRCGRRSFHIQKSRCSACAYPAARKRTYNWSVKAIRRKTTGTGRMRYLRNVPRRFKTCFREGTQATPRNKAAASSS
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
60S ribosomal protein L37-1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL37 family.
Protein: VATH_MOUSE
Sequence: MTKMDIRGAVDAAVPTNIIAAKAAEVRANKVNWQSYLQGQMISAEDCEFIQRFEMKRSSEDKQEMLQTEGSQCAKTFINLMTHISKEQTVQYILTMVDDMLQENHQRVSIFFDYAKRSKSTAWPYFLPMLNRQDPFTVHMAARIIAKLAAWGKELMEGSDLNYYFNWIKTQLSSQKLRGSGVAVETGTISSSDSSQYVQCVAGCLQLMLRVNEYRFAWVEADGVNCIMGVLSNKCGFQLQYQMIFSIWLLAFSPQMCEHLRRYNIIPVLSDILQESVKEKVTRIILAAFRNFLEKSTERETRQEYALAMIQCKVLKQLENLEQQKYDDEDISEDIKFLLEKLGESVQDLSSFDEYSSELKSGRLEWSPVHKSEKFWRENAVRLNEKNYELLKILTKLLEVSDDPQVLAVAAHDVGEYVRHYPRGKRVIEQLGGKQLVMNHMHHEDQQVRYNALLAVQKLMVHNWEYLGKQLQSEQPQTAAARS
What is the function of this protein?
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).  Subunit H is essential for V-ATPase activity, but not for the assembly of the complex (By similarity).  Involved in the endocytosis mediated by clathrin-coated pits, required for the formation of endosomes (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit H, V-ATPase subunit H, Vacuolar proton pump subunit H.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase H subunit family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein.
Protein: ISPF_SALPC
Sequence: MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLMKAAK
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: T2A1_AZOBR
Sequence: MALELADYERKARESVMAFWGNREKARQKQQESGKPDQGERRRDRRKNMDGFCALVIDIIRANGLHRAEIHQKRALLTLPGYFRPTKLWDLLVIQDRRLVAALEFKSQVGPSFGNNFNNRTEEAIGTAHDLWTAYREGAFGQSPRPFVGWLMLVEDAPESNQRRADTSPHFRCSRSSRAHPTYGGMTSSASGSSRSSFTPRPRSSPRRAPPPRQGRIPSPRI
What is the function of this protein?
A P subtype restriction enzyme that recognizes the double-stranded sequence 5'-CTCGAG-3' and cleaves after C-1.
What are the official names of this protein?
Type II restriction enzyme AbrI, R.AbrI, Endonuclease AbrI, Type-2 restriction enzyme AbrI.
What is the protein family that this protein belongs to?
Belongs to the XhoI type II restriction endonuclease family.
Protein: RL9_EDWI9
Sequence: MQVILLDKVANLGSLGDQVNVKAGYARNFLVPMGKAVPATKKNVEFFEARRADLEAKLAETLSAAEARAVKINELATVTIASKAGDEGKLFGSIGTRDIADAVTAAGVAVTKSEVRLPNGVLRTLGDHEVHFQVHSDVFAQLNVVVVAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: NTCP7_DANRE
Sequence: MGLIARVRKEWFIIGIVLVITFAKLQPSVGVKGGPLHPEITITYVAVSVIFFNSGLSLKTEELASALMHVKLHFFVQTFTLVFFPIAIWLLLKVLALTAINEWLLRGLQTVACMPPPVSSAVILTKAVGGNEAAAIFNSAFGSFLGIVVTPLLLLVFLGSSSSVPFTSIFSQLFMTVVVPLIVGQVCRRFLRECLDRRKPPFGAVSSVVLLMIIYSTFCDTFNNPNIELDHLSLLTVVFIIFSIQLSFMALIFFLSTRKSSGFSAADSVAIMFCATHKSLTLGIPMLKIVFEGYEHLSLISVPLLIYHPAQILLGSVLLPSIKTWMSGRQKTLTPI
What is the function of this protein?
Involved in teeth and skeletal development (PubMed:29878199).  Has an essential role in the biosynthesis and trafficking of glycosaminoglycans and glycoproteins to produce a proper functioning extracellular matrix (By similarity).  Required for extracellular matrix mineralization (PubMed:29878199).  Also involved in the regulation of cellular calcium homeostasis (By similarity).  Does not show transport activity towards bile acids or steroid sulfates.
What are the official names of this protein?
Sodium/bile acid cotransporter 7, Na(+)/bile acid cotransporter 7, Solute carrier family 10 member 7.
What is the protein family that this protein belongs to?
Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane.
Protein: RL28_PROMS
Sequence: MSRACELTGAKANNGMAVSHSHIRTKKLQQVNLQKRRLWWEEGKKWVNIKISTKALKSIQKVGLDKFAKSNGVDLKKF
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: SSRP_PROM1
Sequence: MSKKGKKKSKNNSSVDGNRRLAENRQARYEYEILETLETGLELLGTEVKSIRAGKVNLKDGFCLIKKDQIQLHNVHISPHNHAGKFFNHEPLRIKRLLAHRKEIEKLKISLERKGLTIIPLSLYLKGSWIKLKIGVGKGRKTHDKRDREKINDSKRDVANALKRF
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: KTHY_ASFWA
Sequence: MRGILIAIEGINGVGKSTQAMRLKKALECMDYNAVCIRFPNPDTTTGDLILQVLNKMIEMSSEQLHKLFTKHCSEFVAEIAALLKLNFIVIVDRYIWSGLAYAQADGITIETKNTFKPDYTFFLSSKKPLNEKPLTLQRLFETKEKQETIFTNFTIIMNDVPKNRLCTIPATLNKEIIHTMILTKTIKVFDNNSCLNYIKMYDDKYLNVQELNLFDFEWQKCIEDNNDKEEYDDDDFIV
What is the function of this protein?
Catalyzes the conversion of dTMP to dTDP.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: ZN571_HUMAN
Sequence: MPHLLVTFRDVAIDFSQEEWECLDPAQRDLYRDVMLENYSNLISLDLESSCVTKKLSPEKEIYEMESLQWENMGKRINHHLQYNGLGDNMECKGNLEGQEASQEGLYMCVKITCEEKATESHSTSSTFHRIIPTKEKLYKCKECRQGFSYLSCLIQHEENHNIEKCSEVKKHRNTFSKKPSYIQHQRIQTGEKPYECMECGKAFGRTSDLIQHQKIHTNEKPYQCNACGKAFIRGSQLTEHQRVHTGEKPYECKKCGKAFSYCSQYTLHQRIHSGEKPYECKDCGKAFILGSQLTYHQRIHSGEKPYECKECGKAFILGSHLTYHQRVHTGEKPYICKECGKAFLCASQLNEHQRIHTGEKPYECKECGKTFFRGSQLTYHLRVHSGERPYKCKECGKAFISNSNLIQHQRIHTGEKPYKCKECGKAFICGKQLSEHQRIHTGEKPFECKECGKAFIRVAYLTQHEKIHGEKHYECKECGKTFVRATQLTYHQRIHTGEKPYKCKECDKAFIYGSQLSEHQRIHRGEKPYECKQCGKAFIRGSHLTEHLRTHTGEKPYECKECGRAFSRGSELTLHQRIHTGEKPYTCVQCGKDFRCPSQLTQHTRLHN
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 571.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS11_STRA3
Sequence: MAKPTRKRRVKKNIESGVAHIHATFNNTIVMITDVHGNALAWSSAGALGFKGSRKSTPFAAQMAAEAAAKSAQEHGLKTVEVTVKGPGSGRESAIRALAAAGLEVTAIRDVTPVPHNGARPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: RL16_COLP3
Sequence: MLQPKRTKFRKQFKLRNRGLAHVGSSVSFGTFGLKSMERGRMTARQIEAARRAMTRHVKRQGKIWIRVFPDKPITKKPLEVRMGKGKGSVEYWVCQILPGRVLYEMEGVSEEIAREAFALAASKLPFKTTFVTRTAL
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: NCF1B_HUMAN
Sequence: MGDTFIRHIALLGFEKRFVPSQHYVRYMFLVKWQDLSEKVVYRRFTEIYEFHKTLKEMFPIEAGAINPENRIIPHLPAPKWFDGQRAAENHQGTLTEYCGTLMSLPTKISRCPHLLDFFKVRPDDLKLPTDNQTKKPETYLMPKDGKSTATDITGPIILQTYRAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETEDPEPNYAGEPYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQKSGQDVSQAQRQIKRGAPPRRSSIRNVHSIHQRSRKRLSQDAYRRNSVRFLQQRRRQARPGPQSPGSPLEEERQTQRSKPQPAVPPRPSADLILNRCSESTKRKLASAV
What is the function of this protein?
May be required for activation of the latent NADPH oxidase (necessary for superoxide production).
What are the official names of this protein?
Putative neutrophil cytosol factor 1B, NCF-1B, Putative SH3 and PX domain-containing protein 1B.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XYLA_THEPX
Sequence: MEYFKNVPQIKYEGPKSNNPYAFKFYNPDEIIDGKPLKEHLRFSVAYWHTFTANGTDPFGAPTMQRPWDHFTDPMDIAKARVEAAFELFEKLDVPFFCFHDRDIAPEGETLRETNKNLDTIVAMIKDYLKTSKTKVLWGTANLFSNPRFVHGAATSCNADVFAYAAAQVKKALEITKELGGQNYVFWGGREGYETLLNTDMELELDNLARFLHMAVEYAQEIGFEGQFLIEPKPKEPTKHQYDFDAASVHAFLKKYDLDKYFKLNIEANHATLAGHDFQHELRYARINNILGSIDANMGDMLLGWDTDQYPTDIRMTTLAMYEVIKMGGFNKGGLNFDAKVRRASFEPEDLFLGHIAGMDAFAKGFKVAYKLVKDGVFDRFIEERYKSYREGIGAEIVSGKANFKTLEEYALNNPKIENKSGKQELLESILNQYLFSE
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCAP_CPXVB
Sequence: MSLSKEVPSFRWTQSLRRELSSYTQQTKTLVLKDAKMIADSLDFNQVSQVQRVLRKAKRSDADLDKLRDLNQEVDKLMVMKSVQKNTILKLGDLGKDELMDLATDLEKLKRKIGDSGRDGPRPYMGNLTQSQLDKRTQILRVLGFQQQTGVSRGVVRLWDVSNPAKLNNQFGSMPALTIACMTVQGGETMNNVVQALTSLGLLYTVKYPNLEDLEKLTQEHDCLQIITRDESAVNISGYNFSLSAAVKAGASLIDGGNMLETIRVTPNNFSSIIKATLTAKRKENMFVDERPGNRNPYENLLYKVCLSGEGWPYIGSRSQINGRSWDNTSVDLNPKPDPGPRAPEKNGQNLRLSNLTEMQEAVIKEAMQKLDPTNTIWMDIEGPPTDPVELAVFQPTSGYYFHCFRKPHDEKGFKNGSRHSHGILLKDLEDAQPGLLSYILGLLPQNIVITTQGADDIRKLLDVHGRKDIKLVDVRLTNEQSRIFEQQVWERYNSLCRAHNGVIVPKKKNKESNIQKEPHCALLDCIMFQSVLDGHLPDTSLKPLLPDNLVHQAKPAFVM
What is the function of this protein?
Encapsidates the genome, protecting it from nucleases.  The encapsidated genomic RNA is termed the nucleocapsid (NC).  Serves as template for viral transcription and replication.  The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses.  Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of host IRF3, a protein involved in interferon activation pathway, leading to the inhibition of interferon-beta and IRF3-dependent promoters activation.  Encodes also a functional 3'-5' exoribonuclease that degrades preferentially dsRNA substrates and thereby participates in the suppression of interferon induction.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the arenaviridae nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: RK16_SACHY
Sequence: MLSPKRTRFRKQHRGRMNGKSCRGNHICFGRYALQVLEPAWITARQIEAGRRAMTRYARRGGKIWVRIFPDKPVTIRPTETRMGSGKGSPEYWVAVVKPGRILYEMSGVSETVARAAISIAASKMPIRSQFLRLEI
What are the official names of this protein?
50S ribosomal protein L16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RUVB_CHESB
Sequence: MSEPDRIVSAVQRGEDIDTTMRPQSLDEFVGQKTARANLKVFIEAARSRGEALDHVLFVGPPGLGKTTLAQIMARELGVNFRSTSGPVIAKAGDLAALLTNLEERDVLFIDEIHRLNPAVEEILYPAMEDYQLDLIIGEGPAARSVKIDLAKFTLVAATTRLGLLTTPLRDRFGIPIRLEFYTVDELQAIVTRGARIMGMPLAEDGAEEIARRARGTPRIAGRLLRRVRDFAYVAGAENVTRQIADAALSRLEVDALGLDQLDRRYLHMIVENFGGGPVGIETIAAALSEPRDAIEDIIEPYLIQQGFIQRTPRGRVLAAKAWRHLGLNPPKELAQSQINLFEEE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: RS14_BURTA
Sequence: MAKLALIEREKKRARLAQKYAPKRAELKAIIDDASKSDEERYAARLELQQLPRNANPTRKRNRCAITGRPRGTFRKFGLARNKIREIAFRGEIPGLTKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: NADE_BACP2
Sequence: MSLQKKISQELHVQPSIDPKQEIEKRVGFLKDYLKKTGAKGFVLGISGGQDSTLAGRLAQLAASELRQEGKEDAVFIAVRLPHGVQQDEGDAQLALSFIQPDKSWKYDIAPAVTAFSEQYQKDTGGPLSDFNKGNVKARMRMIAQYAVGGEEGLLVIGTDHAAEAVTGFFTKYGDGGADVLPLTGLTKRQGRTLLEALQAPERLYLKKPTADLLDDKPQQTDETELGITYNEIDDYLEGKPVSEQAVEAIEKRYVQSEHKRQVPASMFDDWWK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.