PharMolix/UniProtQA huggingface dataset:
Protein: CH60_PELTS
Sequence: MAGKEIIFREDARRSLEKGVNALAEAVKITLGPKGRNVVLEKKFGSPMIVNDGVTIAREIELSDPFENMGAQLVKEVATKTNDVAGDGTTTACVLAQAIVREGLKNVAAGANPMIIKRGIEKAVDKAVEAIKNSAKTIESKSAIAQVATISANDEMIGNLIADAMEKVGKDGVITVEESKGTTTNLEIVEGMNFDRGYISPYMITDADKMEATLNDPYILITDKKISAVGDLLPLLEKVVQSGKPLLVIAEDVEGEALATLVLNKLRGTFQCVAVKAPGFGDRRKAMLQDIAILTGGTVITEEVGLKLDKATIDQLGRANKVRVKKEETIIVGGAGSTDEITKRVAQIKKQIEETTSEFDKEKLQERLAKLAGGVAVIQVGAATETEMKDKKLRIEDALNATRAAVEEGIVPGGGVAYISALKGLDGLDAGSLDEKTGIDIVRRALEEPLRQIASNAGLEGSVIVEKVKNADPGIGFNALTGEFVNMIDAGIVDPAKVTRTALQNAASIAAMILTTETLVAEKPEKEKDTMGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUG65_SCHPO
Sequence: MTESERTSHLDILYENQRGIMLCGVPYFSEKSLLNFDPAPWVDQHFVASPVSTKTATCPDPSWEWAWQRWYIDMSGDVDESGWQYGFSFTMNNWHGKPVSLHSFVRRRRWIRKRKKKELRRDELPLVPESFTISSSYPIQRSSTQTRSSFEDDSSDFDLSEVTTIPALLRALQDSRIDREKLEALATFLASASIDEKVYVKNCKKDLLKNFVFEHSCRKANELLNASLTAAEASTSQVALRESPTPQD
What is the function of this protein?
Has a role in meiosis.
What are the official names of this protein?
Meiotically up-regulated gene 65 protein.
Protein: TSGA_SALPK
Sequence: MTNSNRIKLTWISFLSYALTGALVIVTGMVMGNIADYFHLPVSSMSNTFTFLNAGILISIFLNAWLMEIVPLKTQLRFGFILMVLAVAGLMFSHSLALFSAAMFVLGLVSGITMSIGTFLITQLYEGRQRGSRLLFTDSFFSMAGMIFPMVAAFLLARSIEWYWVYACIGLVYLAIFILTFGCEFPALGKHAQHSQAPVVKEKWGIGVLFLAVAALCYILGQLGFISWVPEYAKGLGMSLNDAGALVSDFWMSYMFGMWAFSFILRFFDLQRILTVLAGMAAVLMYLFITGTQAHMPWFILTLGFFSSAIYTSIITLGSQQTKVASPKLVNFILTCGTIGTMLTFVVTGPIVAHSGPQAALLTANGLYAVVFVMCFALGFVSRHRQHSSPAAH
What are the official names of this protein?
Protein TsgA.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TsgA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SP4_HUMAN
Sequence: MSDQKKEEEEEAAAAAAMATEGGKTSEPENNNKKPKTSGSQDSQPSPLALLAATCSKIGTPGENQATGQQQIIIDPSQGLVQLQNQPQQLELVTTQLAGNAWQLVASTPPASKENNVSQPASSSSSSSSSNNGSASPTKTKSGNSSTPGQFQVIQVQNPSGSVQYQVIPQLQTVEGQQIQINPTSSSSLQDLQGQIQLISAGNNQAILTAANRTASGNILAQNLANQTVPVQIRPGVSIPLQLQTLPGTQAQVVTTLPINIGGVTLALPVINNVAAGGGTGQVGQPAATADSGTSNGNQLVSTPTNTTTSASTMPESPSSSTTCTTTASTSLTSSDTLVSSADTGQYASTSASSSERTIEESQTPAATESEAQSSSQLQPNGMQNAQDQSNSLQQVQIVGQPILQQIQIQQPQQQIIQAIPPQSFQLQSGQTIQTIQQQPLQNVQLQAVNPTQVLIRAPTLTPSGQISWQTVQVQNIQSLSNLQVQNAGLSQQLTITPVSSSGGTTLAQIAPVAVAGAPITLNTAQLASVPNLQTVSVANLGAAGVQVQGVPVTITSVAGQQQGQDGVKVQQATIAPVTVAVGGIANATIGAVSPDQLTQVHLQQGQQTSDQEVQPGKRLRRVACSCPNCREGEGRGSNEPGKKKQHICHIEGCGKVYGKTSHLRAHLRWHTGERPFICNWMFCGKRFTRSDELQRHRRTHTGEKRFECPECSKRFMRSDHLSKHVKTHQNKKGGGTALAIVTSGELDSSVTEVLGSPRIVTVAAISQDSNPATPNVSTNMEEF
What is the function of this protein?
Binds to GT and GC boxes promoters elements.  Probable transcriptional activator.
What are the official names of this protein?
Transcription factor Sp4, SPR-1.
What is the protein family that this protein belongs to?
Belongs to the Sp1 C2H2-type zinc-finger protein family.
Protein: MNME_MICAN
Sequence: MLNTGDTIAAIATAIVPEQGSIGIVRLSGSEAVAIARRLFHSPNRQKWQSHRLLYGYIRHPQSQAIIDEALLLLMLAPRSFTREDVVEFHCHGGIMPVQQVLQLCLENGARLAQAGEFSLRAFLNGRIDLTQAESVVDLVGARSPQAAQFALAGLQGKLAQPIRHLRATCLDILAEIEARIDFEEDLPPLDHAAVLHSIEQVFCQVNLILATAERGELLRSGLKVAIVGRPNVGKSSLLNAWSRSDRAIVTDLPGTTRDIVESQLVVAGIPVQVLDTAGIRSASDRVEQIGVERSRQTARSADLVLLTVSAESGWTQEDEEIYRSVSDRRLILVINKIDLANPETVIYPAEIKRVVKLSAAQNQGIEDLEKSLINAVQNQELQAANLDLAINQRQAAALTRAKIALQQVKKTIDQNLPFDFWSIDLRTAIQSLGEITGEEVTESVLDRIFSRFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG4_PIG
Sequence: METQRASLCLGRWSLWLLLLALVVPSASAQALSYREAVLRAVDRLNEQSSEANLYRLLELDQPPKADEDPGTPKPVSFTVKETVCPRPTRQPPELCDFKENGRVKQCVGTVTLDQIKDPLDITCNEVQGVRGGRLCYCRGWICFCVGRG
What is the function of this protein?
Microbicidal activity.
What are the official names of this protein?
Protegrin-4, PG-4.
What is the protein family that this protein belongs to?
Belongs to the cathelicidin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS5_NICPL
Sequence: HTAGRYQAKRFRKAQCPIVERLTNSLMMHGRNNGKKLMAVRIVKHAMEIIHLLTDLNPIQVIVDAVINSGPREDATRIGSAGVVRRQAVDISPLRRVSQAIYLLTTGARESAFRNIKTIAECLADELINAAKGSSNSYAIKKKDEIERVAKANR
What are the official names of this protein?
40S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: MSD2_AMABI
Sequence: MSDINTARLPFYQFPDFKYPCVGDDIEMVLARGE
What is the function of this protein?
Probable toxin that belongs to the MSDIN-like toxin family responsible for a large number of food poisoning cases and deaths (PubMed:18025465).
What are the official names of this protein?
MSDIN-like toxin proprotein 2.
What is the protein family that this protein belongs to?
Belongs to the MSDIN fungal toxin family.
Protein: PNP_EHRCR
Sequence: MFNLIRRSAEWGGKTLVLESGKIARQASGAVMVSYAGTTVLATVVTGKTKEPVDFLPLTVQFVAKSYAVGKIPGGFLKREGKPSDRETLISRLIDRSIRPLFPAGFYDEISIVCNLLSYDTVTPPEVTALVGATAALSISGVPFNGLVVGARVGYLPSEGKYLLNASADEMLCSSLDLFLSGNEDSVLMVESEASELSESQMLGAITFGHQHCQEVINLIKEFSHESGQTPIDFIPHDISSLVSDIESSYKEDFSLAYSNTIKKERVLKLEELRGKVLSEVADKYSAGDVECSDQDIVTALKTFERSLVRSKIIDTSSRIDGRAFDEIRDIEIEVDVLPKAHGSALFTRGNTQALVVTALGTPQDEQIVDDLDGDRRENFLLHYNFPPYAVGESAALRAPGRREIGHGKLAWRAIRYVLPEKSDFPYTIRVVSEITESDGSSSMATVCGASLALMDTGVPIKSPVAGIAMGLIKEDDRFIILSDILGDEDHLGDMDFKVAGTAEGVTALQMDMKISGIDIDIIEKALLQAKDGRMHILSKMNAVIQESRNRIKNHAPRIESIFINKDKIRNVIGSGGKNIRDICEKTGAKIEIIQDGTVMIYAVNNEAVEYAKSMIMDIVTEPEIGKVFEGTVVEIMKFGAFVSFLGGKKGLVHISEIRNEHISSVGSVISLNDKVKVLVIGIDREHIQLSMRRVDQESGEPIDGELYNIRKNSFSDDSCGSTGGSSFKESYNPNSRHGSHEKKRSGGSSRSSRRNSNGPNYYREDLPSSNGFGNNNRSFSNSRNGHDVPRKPRFF
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_MARSD
Sequence: MGQKVHPYGFRLGYTKNWLSRWFSSKDYPAFVYEDDSIRKYVKEKIFHAGVSKIEIERAGGKIRLIIHTARPGIIIGRKGVEIEKLREDLRRKFNKEFALEVSEIRRPETDAQLVAENIAQQLERRVAFRRAMKRIVGLARKFGAEGIKVACAGRLAGAEIARTEWYRDGRVPLQTLRADIDYGVARANTTYGVIGIKVWIFKGEILDHEVEQ
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: EX7L_STRA1
Sequence: MSDYLSVSTLTKYLKLKFDKDPYLERVYLTGQVSNFRRRPNHQYFSLKDDKSVIQATMWSGHFKKLGFELEEGMKVNVVGRVQLYEPSGSYSIIVEKAEPDGIGALAIQFEQLKKKLSQAGYFDDRHKQLIPQFVRKIGVVTSPSGAVIRDIITTVSRRFPGVEILLFPTKVQGEGAAQEIAQTIALANEKKDLDLLIVGRGGGSIEDLWAFNEECVVEAIFESRLPVISSVGHETDTTLADFVADRRAATPTAAAELATPVTKIDILSWITERENRMYQSSLRLIRTKEERLQKSKQSVIFRQPERLYDGFLQKLDNLNQQLTYSMRDKLQTVRQKQGLLHQKLQGIDLKQRIHIYQERVVQSRRLLSSTMTSQYDSKLARFEKAQDALISLDSSRIVARGYAIIEKNHTLVSTTNGINEGDHLQVKMQDGLLEVEVKDVRQENI
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HICB2_PHOLL
Sequence: MSKNMRYPVKFEHDETGWAVMFPDIPEALTGGDTREEALAMAQDALVTAFDFYFEDRREIPTPSTKGEAFVEVPASIAAKVLLLNTMLQTRTSNAELARLLGTRPQEIQRIVSLSHSTKIDTIANALNALGKHLELVAI
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system.  Functions as an mRNA interferase antitoxin preventing effects of the HicA 2 toxin (By similarity).
What are the official names of this protein?
Antitoxin HicB 2.
What is the protein family that this protein belongs to?
Belongs to the HicB antitoxin family.
Protein: KTHY_CHLFF
Sequence: MFIVIEGCEGSGKSSLTELLKNRLITEGKSVIATREPGGSPLGEQVRNWILNPSLPGISPYTELFLFLASRAQHITEKIIPALESGKIVICDRFHDSTIVYQGIAEGLGKEYVTNLCHHVVGEKKFLPDLTCLLDIPVDTGIKRKQQQKSLDKFEDKPLVYHNKIREGFLSLAEANPENYLILDGRQPLEASLNKVMTAYTELALCK
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: KPTA_RHOBA
Sequence: MKADKQLVSTSKFLSLVLRHQPGVIGMTLDEQGWLEIDGLIANANTRGKKLTLELIHEVVATNDKKRFVLSDDGLRIRASQGHSVAGVDLNLTEANPPATLYHGTVDAFLPRIREQGLQKRSRNHVHLSADEATATNVGSRRGKPKLLLIAAQRMHQDGHIFYLSENEVWLVDSVPPTYLTFPT
What is the function of this protein?
Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P).  May function as an ADP-ribosylase.
What are the official names of this protein?
Probable RNA 2'-phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the KptA/TPT1 family.
Protein: FA8_PIG
Sequence: MQLELSTCVFLCLLPLGFSAIRRYYLGAVELSWDYRQSELLRELHVDTRFPATAPGALPLGPSVLYKKTVFVEFTDQLFSVARPRPPWMGLLGPTIQAEVYDTVVVTLKNMASHPVSLHAVGVSFWKSSEGAEYEDHTSQREKEDDKVLPGKSQTYVWQVLKENGPTASDPPCLTYSYLSHVDLVKDLNSGLIGALLVCREGSLTRERTQNLHEFVLLFAVFDEGKSWHSARNDSWTRAMDPAPARAQPAMHTVNGYVNRSLPGLIGCHKKSVYWHVIGMGTSPEVHSIFLEGHTFLVRHHRQASLEISPLTFLTAQTFLMDLGQFLLFCHISSHHHGGMEAHVRVESCAEEPQLRRKADEEEDYDDNLYDSDMDVVRLDGDDVSPFIQIRSVAKKHPKTWVHYISAEEEDWDYAPAVPSPSDRSYKSLYLNSGPQRIGRKYKKARFVAYTDVTFKTRKAIPYESGILGPLLYGEVGDTLLIIFKNKASRPYNIYPHGITDVSALHPGRLLKGWKHLKDMPILPGETFKYKWTVTVEDGPTKSDPRCLTRYYSSSINLEKDLASGLIGPLLICYKESVDQRGNQMMSDKRNVILFSVFDENQSWYLAENIQRFLPNPDGLQPQDPEFQASNIMHSINGYVFDSLQLSVCLHEVAYWYILSVGAQTDFLSVFFSGYTFKHKMVYEDTLTLFPFSGETVFMSMENPGLWVLGCHNSDLRNRGMTALLKVYSCDRDIGDYYDNTYEDIPGFLLSGKNVIEPRSFAQNSRPPSASQKQFQTITSPEDDVELDPQSGERTQALEELSVPSGDGSMLLGQNPAPHGSSSSDLQEARNEADDYLPGARERNTAPSAAARLRPELHHSAERVLTPEPEKELKKLDSKMSSSSDLLKTSPTIPSDTLSAETERTHSLGPPHPQVNFRSQLGAIVLGKNSSHFIGAGVPLGSTEEDHESSLGENVSPVESDGIFEKERAHGPASLTKDDVLFKVNISLVKTNKARVYLKTNRKIHIDDAALLTENRASATFMDKNTTASGLNHVSNWIKGPLGKNPLSSERGPSPELLTSSGSGKSVKGQSSGQGRIRVAVEEEELSKGKEMMLPNSELTFLTNSADVQGNDTHSQGKKSREEMERREKLVQEKVDLPQVYTATGTKNFLRNIFHQSTEPSVEGFDGGSHAPVPQDSRSLNDSAERAETHIAHFSAIREEAPLEAPGNRTGPGPRSAVPRRVKQSLKQIRLPLEEIKPERGVVLNATSTRWSESSPILQGAKRNNLSLPFLTLEMAGGQGKISALGKSAAGPLASGKLEKAVLSSAGLSEASGKAEFLPKVRVHREDLLPQKTSNVSCAHGDLGQEIFLQKTRGPVNLNKVNRPGRTPSKLLGPPMPKEWESLEKSPKSTALRTKDIISLPLDRHESNHSIAAKNEGQAETQREAAWTKQGGPGRLCAPKPPVLRRHQRDISLPTFQPEEDKMDYDDIFSTETKGEDFDIYGEDENQDPRSFQKRTRHYFIAAVEQLWDYGMSESPRALRNRAQNGEVPRFKKVVFREFADGSFTQPSYRGELNKHLGLLGPYIRAEVEDNIMVTFKNQASRPYSFYSSLISYPDDQEQGAEPRHNFVQPNETRTYFWKVQHHMAPTEDEFDCKAWAYFSDVDLEKDVHSGLIGPLLICRANTLNAAHGRQVTVQEFALFFTIFDETKSWYFTENVERNCRAPCHLQMEDPTLKENYRFHAINGYVMDTLPGLVMAQNQRIRWYLLSMGSNENIHSIHFSGHVFSVRKKEEYKMAVYNLYPGVFETVEMLPSKVGIWRIECLIGEHLQAGMSTTFLVYSKECQAPLGMASGRIRDFQITASGQYGQWAPKLARLHYSGSINAWSTKDPHSWIKVDLLAPMIIHGIMTQGARQKFSSLYISQFIIMYSLDGRNWQSYRGNSTGTLMVFFGNVDASGIKHNIFNPPIVARYIRLHPTHYSIRSTLRMELMGCDLNSCSMPLGMQNKAISDSQITASSHLSNIFATWSPSQARLHLQGRTNAWRPRVSSAEEWLQVDLQKTVKVTGITTQGVKSLLSSMYVKEFLVSSSQDGRRWTLFLQDGHTKVFQGNQDSSTPVVNALDPPLFTRYLRIHPTSWAQHIALRLEVLGCEAQDLY
What is the function of this protein?
Factor VIII, along with calcium and phospholipid, acts as a cofactor for factor IXa when it converts factor X to the activated form, factor Xa.
What are the official names of this protein?
Coagulation factor VIII, Procoagulant component.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: RPP14_MOUSE
Sequence: MPATAYERVVYKSPSEYHYMKVCLEFQEHGVGLNVAQFKQLLVSALRDLFGEVGAALPVDVLTYDEKTLSAILRICSSGLVKLWSSLTLFGAYKSKKCAFRVIQVSPFLLALSGNSREQVLD
What is the function of this protein?
Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein subunit p14.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: COAE_CAMJE
Sequence: MKNAFFVTASIACGKSTFIEIANSLGFKSISADKIAHKILDENALELEKIFSPFSLKNLLKKEKKIDRKILGEIVFNNKEAKKILENFTHPKIRAKILEQMQILDKENKAFFVEIPLFFESGAYENLGKVIVIYTPKELSLKRIMQRDKLSLEAAKARLDSQIDIEEKLKKADFIIKNTNSYADFRQECVKVIQEISKGNM
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCPP_SHEON
Sequence: MQQNIIKVIVGSKNPVKVNAAANAMTLLFPEYQIQTIGMDAPSGVPAQPMTDSDTRQGAINRVNYCQQHAEADYYFAMEGGVDHFEFGPATFAYIAIAHQQRLSIGRGALLPLPRQVYQALEAGEELGHVMDRLFNTVNIKQKGGAIGLLTHGHATRESNYTQALILAMAPFLNPEIYL
What is the function of this protein?
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives.  Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine/xanthosine triphosphatase, ITPase/XTPase, Non-canonical purine NTP phosphatase, Non-standard purine NTP phosphatase, Nucleoside-triphosphate phosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the YjjX NTPase family.
Protein: UVRC_METFK
Sequence: MFDPKPVLKNLPNLPGVYRMINAQDEVIYVGKARDLKKRVSSYFQKNLPSARTRLMVSNIARIETTVTRSEAEALLLENNLIKGFMPRYNVLFRDDKSYPYIALTGDTFPRLAFHRGAQRKGSSYFGPFPNAVAVRESIQLLQKVFRLRTCENTVFANRSRPCLLHQIERCTAPCVGFISEEDYRRDVMHASLFLQGKEQQVMDELGEKMNEAAEKMEYELAAVYRDRIQSLRQVQAKQFVSDFNVSDADVIACAELEGQWCVNLVMIRGGHHLGDKSFFPKNADGADLETTMEAFLEQHYMAGAIPPLLIVGASLETAALEEVFSEQAGRRIRINTHPIGDKRVWLKMAHTNAQLALSQRIAQQANQQSRLNALREALGLPESTERIECFDISHTMGEATVASCVVFDKGAMQSSEYRRYNITGITPGDDYAAMRDVLTRRYRKVAAGEGKRPDLVFIDGGKGQLGVAVEVLNEVGLPDIQLVGIAKGEERKPGLEQMFFPEREEPVSLKKDHPGLHLLQQIRDEAHRFAITGHRAKRGKARMHSSLEDISGIGAKRRKSLLTRFGGLDGVKNASVDEIAQVDGISHALAQKIYEELH
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREF_ACTPJ
Sequence: MGQLGALLHLVDPTLPIGGFNHSNGLETFVQQGKVNSRASLEEYVQTQLMQNWIYNDGAYLSLAFDAMANHDLGRLLQLDQELAASKIARESREGSYKLGVRLLKIFIRYENHPLLSEFQQAVSEKRCQGYFPIVFAMVAQAMNLDKAETLYAFYYNAAVGVVTNGVKLVPLSQMDGQDILFALRTPLAQAVENSLNPDLDWLGAATLASDIRSMQHEQLYTRLYMS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDPAS_SULIA
Sequence: MSIAYDLLLSILIYLPAFVANGSGPFIKRGTPIDFGKNFVDGRRLFGDGKTFEGLIVALTFGTTVGVIISKFFTAEWTLISFLESLFAMIGDMIGAFIKRRLGIPRGGRVLGLDQLDFVLGASLILVLMRVNITWYQFLFICGLAFFLHQGTNYVAYLLKIKNVPW
What is the function of this protein?
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP.  This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
CDP-archaeol synthase, CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-archaeol synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BIOF_CROS8
Sequence: MTWQARIDAALRAREASHSLRRRVVCTPAPGGALVHQGVRYRNFSGNDYLGLSQHPALIAAWQQGAQTYGVGSGASGHVSGYSDAHQSLENALAHWLGFDRALLFISGFAANQAVVAALMQQSDRILADRLSHASLLEAASHSPATLRRFAHNDSGALAALLGKPCDGLTLVFTEGVFSMDGDSAPLADIAGIAQGAQTLLMVDDAHGVGVQGREGRGSCDVAGIRPDLLLVTFGKAFGLSGAALLCSAPMADYLLQTARHLIYSTAMPAAQACALNAALTVIREGDDLRARLARNIARFRAGAASLPLTLADSQTAIQPLIVGENSAALTLAEKLRERGCWVTAIRPPTVPAGTARLRLTLSAAHQDEDIDALLEALYDGCR
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: VIT_TAKPA
Sequence: IVMLKNDNVEQKHINIKIADIDIDLFPKSGNIGVKVNGVEIPMENLPYYHPTVKIQIRQKGEGISVVAPSLGLSEVYMDSKSWKVEVVDWMKGQTCGLCGKADGEIKQEFRMPNGHLTKNAVTYAHSWILAAESCRDNSECRIKLDSVELEKRAVIYGQESRCFSVEPVLRCLPGCFPVKTTSVTVGFHCVAADSNVNKSEVLRGIQGKRVDLREKADAHLACSCTAQC
What is the function of this protein?
Probably binds tetrodotoxin in the ovary.
What are the official names of this protein?
Vitellogenin.
Protein: Y423_IDILO
Sequence: MQEVVTGKRAELLSAEFLKKNNLTIICKNYRIDGGEVDIIARDGHYWVFCEVKFRDDESFAAVIEQIQPQQCRRIRYTARHYLLSNNIDEHTAAIRFDVIAIVGQPTKIEWFKDAF
What are the official names of this protein?
UPF0102 protein IL0423.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: MVD1_ASPFU
Sequence: MAATSDRTVYRATTTAPVNIAVIKYWGKRDASLNLPTNSSLSVTLSQRSLRTLTTASCSAIYPAADELILNGKPQDIQTSKRTLACLSNLRSLRQALENADPSLPKLSTLPLRIVSENNFPTAAGLASSAAGFAALVRAVADLYQLPQSPLELSRIARQGSGSACRSLMGGYVAWRAGEREDGSDSLAEEVAPASHWPEMRAIILVVSAEKKDVPSTEGMQTTVATSSLFATRAASVVPERMAAIETAIQNKDFATFAEITMRDSNSFHATCLDSWPPIFYMNDVSRAAVRLVHDINRAVGRTVCAYTFDAGPNAVIYYLEKDSEVVAGTIKAILGPNTEGFDGPFYDILKNVTASVVPLEKVDSRAVEILKNGISRVILTGVGEGPISVEDHLVSATGDILAS
What is the function of this protein?
Diphosphomevalonate decarboxylase; part of the second module of ergosterol biosynthesis pathway that includes the middle steps of the pathway (By similarity).  Mvd1 converts diphosphomevalonate into isopentenyl diphosphate (By similarity).  The second module is carried out in the vacuole and involves the formation of farnesyl diphosphate, which is also an important intermediate in the biosynthesis of ubiquinone, dolichol, heme and prenylated proteins.  Activity by the mevalonate kinase erg12 (AFUA_4G07780) first converts mevalonate into 5-phosphomevalonate.  5-phosphomevalonate is then further converted to 5-diphosphomevalonate by the phosphomevalonate kinase erg8 (AFUA_5G10680).  The diphosphomevalonate decarboxylase mvd1 (AFUA_4G07130) then produces isopentenyl diphosphate.  The isopentenyl-diphosphate delta-isomerase idi1 (AFUA_6G11160) then catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).  Finally the farnesyl diphosphate synthase erg20 (AFUA_5G02450) catalyzes the sequential condensation of isopentenyl pyrophosphate with dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate (PubMed:16110826, PubMed:22106303) (Probable).
What are the official names of this protein?
Diphosphomevalonate decarboxylase mvd1, Ergosterol biosynthesis protein mvd1, Mevalonate pyrophosphate decarboxylase, Mevalonate-5-diphosphate decarboxylase, MDDase.
What is the protein family that this protein belongs to?
Belongs to the diphosphomevalonate decarboxylase family.
Protein: GLO2_ALIF1
Sequence: MLSVKSIPAFNDNYIWLIHNNDNHCVVVDPGDATPVLECIKEHDFILDAILITHHHHDHIGGVPELVRQFPNVNVVGPENEPIPTLTHPVGDGDFVELFDEQFMVLGVPGHTNGHVAYIGDEKLFCGDALFSAGCGRLFEGTAEQMFNSLQKMAALPDETEVYCAHEYTASNLAFALAVEPDNDYLLRYREKVLHLRAHGKSTIPSTLQREKLINPFLRTSEANVKKSVASKVQDSTEVEIFTALRRWKDEF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: KDGT_ECOL6
Sequence: MQIKRSIEKIPGGMMLVPLFLGALCHTFSPGAGKYFGSFTNGMITGTVPILAVWFFCMGASIKLSATGTVLRKSGTLVVTKIAVAWVVAAIASRIIPEHGVEVGFFAGLSTLALVAAMDMTNGGLYASIMQQYGTKEEAGAFVLMSLESGPLMTMIILGTAGIASFEPHVFVGAVLPFLVGFALGNLDPELREFFSKAVQTLIPFFAFALGNTIDLTVIAQTGLLGILLGVAVIIVTGIPLIIADKLIGGGDGTAGIAASSSAGAAVATPVLIAEMVPAFKPMAPAATSLVATAVIVTSILVPILTSIWSRKVKARAAKIEILGTVK
What is the function of this protein?
Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell.
What are the official names of this protein?
2-keto-3-deoxygluconate permease, KDG permease.
What is the protein family that this protein belongs to?
Belongs to the KdgT transporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y755_SYNY3
Sequence: MTEVLRVGQPAPDFTATAIVDQSFQTVKLSTYRGKYLVLFFYPLDFTFVCPTEIIAFSDRHSEFTALDTEVVGISVDSEFSHLAWIQTERKMGGIGNINYPLVSDLKKEISQAYNVLEPDAGIALRGLFIIDREGILQYATVNNLSFGRSVDETLRVLKAIRHVQSHPNEVCPVDWQEGDKTMIPDPEKAKTYFETVAEP
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Putative peroxiredoxin sll0755, Thioredoxin reductase.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.