PharMolix/UniProtQA huggingface dataset:
Protein: EFP_ECO55
Sequence: MATYYSNDFRAGLKIMLDGEPYAVEASEFVKPGKGQAFARVKLRRLLTGTRVEKTFKSTDSAEGADVVDMNLTYLYNDGEFWHFMNNETFEQLSADAKAIGDNAKWLLDQAECIVTLWNGQPISVTPPNFVELEIVDTDPGLKGDTAGTGGKPATLSTGAVVKVPLFVQIGEVIKVDTRSGEYVSRVK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HCYE_SEPOF
Sequence: HGLPAQCPNADGTMVHTCCLHGMPTFKLNFDSHFTIKTVVAQNGTELPESILPEATIDRIPPSSHDLESVRGNLVRKNVDRLSLQEVNSLVHALKRMQKDRSSDGFESIACFHALPPLCPNPTAKHRYACCLHGMATFPQWHRLYVVQFEQSLNRHGATVGVPYTDWTYPMKEVPHLLTSEKYTDPFTAVETFNPFNHGHLSLLSPET
What is the function of this protein?
Hemocyanins are copper-containing oxygen carriers occurring freely dissolved in the hemolymph of many mollusks and arthropods.
What are the official names of this protein?
Hemocyanin, units E and F.
What is the protein family that this protein belongs to?
Belongs to the tyrosinase family. Hemocyanin subfamily.
Protein: SCL6_LEIHE
Sequence: VRDGYIAQPENCVYHCIPDCDTLCKDNGGTGGHCGFKLGHGIACWCNALPDNVGIIVDGVKCHK
What is the function of this protein?
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission.  This toxin is highly toxic to insects and mice, and inhibits the binding of alpha-toxin to cockroach neuronal membranes.
What are the official names of this protein?
Alpha-like toxin Lqh6, Lqh VI, LqhVI.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MAEA_ARATH
Sequence: MEIDSATNGNSDTVMTESAATITPSPVVVSSSRSNQFTESLKLEHQLLRVPFEHYKKTIRTNHRSFEKEVSTIVNGVGELADSDWSKDDTVSRLTCLVTRLQGLKRKLEEGSNVENLQAQRCRARIDHLDSVDVENITEWNNTKLKRILVDYMLRMSYFETATKLSESSNIMDLVDIDIFREAKKVIDALKNREVASALTWCADNKTRLKKSKSKFEFQLRLQEFIELVRVDTAESYKKAIQYARKHLASWGTTHMKELQHVLATLAFKSTTECSKYKVLFELRQWDVLVDQFKQEFCKLYGMTMEPLLNIYLQAGLSALKTPYGLEEGCTKEDPLSQENFRKLALPLPFSKQHHSKLVCYISKELMDTENPPQVLPNGYVYSTKALKEMAEKNGGKITCPRTGLVCNYTELVKAYIS
What are the official names of this protein?
Protein MAEA homolog.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associates predominantly in the form of large cytoplasmic complexes.
Protein: PRDB_ACESD
Sequence: MSDLTVVKGLQSEIYVPITPPPVWTPVTKELKDMTVALVTAAGVHMKADKRFNLAGDFSFRVIPGDASVNDMMVSHGGYDNGDVNKDINCMFPIDPMRTLAKEGFIKALAPINIGFMGGGGDQKKFSEETGPEIARQLKEEGVDAVLLTAGUGTCHRSAVIVQRAIEESGIPTIIIAALPPVVRQNGTPRAVAPLVPMGANAGEPNNPEMQKAICTDSLKQLVEIPSAGKIVPLPYEYVAKV
What is the function of this protein?
D-proline reductase catalyzes the reductive cleavage of a C-N bond in D-proline resulting in the formation of 5-aminovalerate.  The alpha subunit has been shown to bind D-proline, presumably via the pyruvoyl group.
What are the official names of this protein?
D-proline reductase subunit gamma, D-proline reductase 26 kDa subunit.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BRX1_CAEEL
Sequence: MGKFSKIKKVQEEESAHQKMEWEAAGAKDSSSDDSSDESDNDDQPKQATEETRKRAELWTNRERVLVLCSRGADVRTRYLMKDIKDLLPHAKGDSKLDQQKSLNVLNEIAEMKNCTKVMYFESRKRKDTYLWMSNVEKGPSIKFLVHNVHTMKELKMSGNCLRASRPVLSFDDAFDKKPQLKLIKAVLMQTLGTPHHHPRSQPFVDHVFNFSVGEGDKIWFRNFQIVDESLQLQEVGPRFVLEMVRLFAGSFEGAVLYDNPNYVSPNVIRREHRKGQHSYIEKQLAVKASNIKQAKVTEILAEKTVDLVGKEFDTQNNAAADSEAAAQITAQIEKRRVRKKKSQASKYTGSD
What is the function of this protein?
Required for biogenesis of the 60S ribosomal subunit.
What are the official names of this protein?
Ribosome biogenesis protein BRX1 homolog, Brix domain-containing protein 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the BRX1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RL5_LISMO
Sequence: MNRLKDQYLKEIVPALMSKFNYDSVMEVPKIDKIVINTGVGDATANAKVLDSAVEELALITGQKPVITKAKNSIAGFRLREGMPIGAKVTLRGERMYDFLDKLVTVSLPRVRDFRGVSKKAFDGRGNYTLGVREQLIFPEIDYDQVSKVRGMDVVIVTTAKSDEESHELLTQLGMPFQK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: SMC_RHOPA
Sequence: MKLTRLRLHGFKSFVEPTDFMIEPGLTGVVGPNGCGKSNLVEALRWAMGETSHKSLRATDMDAVIFAGSGNRPARNHAEVVMSIDNSDRTAPAALNDADTLDISRRIEREAGSVYRINGREVRARDVQLLFADAATGARSPALVHQGKIGEIIQAKPEQRRRVLEDAAGVAGLHARRHEAELRLKAAETNLTRVEDVIGQLSTQVDGLKKQARQAIRFREVAAKVRKTEAMLYHLRWRDAQAEVGAAAEVHDLGVRQLAECTRVQAEASRIQADRASTLPSLREAEARAAAGLQRLINAREQLDREEARAKERVVELERRLTQFSSDVAREQQQAIDADAALERLDTEDVELREEILERVEKRSGVDERVAEADASLGEAEQLFAELTTQLAELTARRNQFEQSVRTHRDRLARLDTEIKNVESEIDRLSAETSGAGDLTELAEAVEIAQELLAEQEGAVQEAEAAQIAARQTLDGSRAPLVDAEKKVQRLETEAKTISKILNGETKNLWPPIIDGITVAKGYEKAIGAVLGDDLDAPVDPSAPMRWTDVGVQPEDPALPEGVEALAQHVTAPPELARRLAQIGVVTKERGNELCEQLKTGQRLVSLDGDVWRWDGFVASAHAPTGAARRLAERARLTDIENELEQARIEATAKRQALETAEADLKMAAAAETASRESLRGARREVDAARERFAAAEREVNRHAARKSALAEAQSRLATDRAEAEAALENAEAQIADLEPNTEAEARLAAVRGDIDGRRRIAAQIRAEAQALAREAELADKRLQAIAAERMDWQKRKAGAASQIATVEERVAELTAERAELENAPEVFAEKRSAVITEIEFAEADRRAAADALAAAEQAMSETDRLAKASLEQLSSAREACARAEERMEAARRRLEDVEREIRDMLEVEPQAAAQLAEIVEGAELPPLAEIEESLDKLRRDRERLGAVNLRAEEELNEVETQHGTLAAERDDLVEAIKKLRTGIQSLNKEARERLLASFDVVNGHFKRLFTTLFGGGEAELKLIESDDPLEAGLDIIAKPPGKKPQSLSLLSGGEQALTAMALIFAVFLTNPSPICVLDEVDAPLDDHNVERFCDLLTDMAKTTETRFITITHNPITMARMNRLFGVTMAERGVSQLVSVDLQGAVDILDQNVA
What is the function of this protein?
Required for chromosome condensation and partitioning.
What are the official names of this protein?
Chromosome partition protein Smc.
What is the protein family that this protein belongs to?
Belongs to the SMC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UP1_ICHTR
Sequence: DWTYTTWLWWWWWWT
What are the official names of this protein?
Unknown protein 1.
What are the subcellular locations of this protein?
Secreted.
Protein: UBID_PARPJ
Sequence: MKYKDLRDFVGRLETIGELRRISQNVSPVLEMTELCDRVLRAGGPALLFESKAQHEFPVLGNLFGTPRRVALGMGVDAQAGEGDGAALESLRDVGRLLSALKEPEPPKGLKDAGKLFSLAKAVWDMAPKTVSAPPCQEIVWEGNDVDLARLPIQTCWPGDAGPLITWGLTVTKGPNKSRQNLGIYRQQLIGRNKLIMRWLAHRGGALDFREFALQNPGKPYPVAVVLGADPATILGAVTPVPDTLSEYQFAGLLRGGRTELAKCITPGVDGLQVPARAEIVLEGFIYPQEGAPSPAPAGAPPRPVKGASAAYEHALEGPYGDHTGYYNEQEWFPVFTVERITMRRDAIYHSTYTGKPPDEPAVLGVALNEVFVPLLQKQFSEITDFYLPPEGCSYRMAIVQMKKSYPGHAKRVMFGVWSFLRQFMYTKFIVVVDEDVNIRDWKEVIWAITTRIDPARDTVLVDRTPIDYLDFASPVAGLGSKMGLDATNKWPGETDREWGRPIVMDDAVKQRIDTLWNELGL
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: EFEO_ECOL6
Sequence: MTINFRRNALQLSVAALFSSAFMANAADIPQVKVTVTDKQCEPMIITVNAGKTQFIIQNHSQKALEWEILKGVMVVEERENIAPGFSQKMTANLQPGEYDMTCGLLTNPKGKLIVKGEATADAAQSDALLSLGGAITAYKAYVMAETTQLVTDTKAFTDAIKAGDIEKAKALYAPTRQHYERIEPIAELFSDLDGSIDAREDDYEQKAADPKFTGFHRLEKALFGDNTTKGMDKYADQLYTDVVDLQKRISELAFPPSKVVGGAAGLIEEVAASKISGEEDRYSHTDLWDFQANVEGSQKIVDLLRPQLQKANPELLAKVDANFKKVDTILAKYRTKDGFENYDKLTDADRNALKGPITALAEDLAQLRGVLGLD
What is the function of this protein?
Involved in Fe(2+) uptake.  Could be an iron-binding and/or electron-transfer component (By similarity).
What are the official names of this protein?
Iron uptake system component EfeO.
What is the protein family that this protein belongs to?
Belongs to the EfeM/EfeO family.
What are the subcellular locations of this protein?
Periplasm.
Protein: TBL36_ARATH
Sequence: MATSETRVLFLSLCLILGKVVLSQFDELWLVGDDDPLNALQTRRERREERCDYSVGKWTFDETYPLYDSSCPYLSSALSCQRNGRPDSYYQKWRWIPKACSLPRFDALKFLGKMRGKRIMLVGDSMMRNQWESLVCLVQSVLPTHRKKLTYNGPTMSFHSLDFETSIEFCWAPLLVELKRGVDRKRVLHLDSIEDNARYWRGVDVLVFDSAHWWTHSQRWSSWDYYMDGNKIFKAMDPMVAYERGLTTWAKWVEINLDPSKTKVIFRTVSPRESGQMCYNQKHPLPSLSSSTKPHVPQQSRVLNKVLRTMKYRVYLYDITTMSAYRRDGHPSVFKRAMHEEEKHHRIAGPSSDCSHWCLPGVPDIWNEMLSSIILTNAV
What is the function of this protein?
May act as a bridging protein that binds pectin and other cell wall polysaccharides.  Probably involved in maintaining esterification of pectins (By similarity).  May be involved in the specific O-acetylation of cell wall polymers (By similarity).
What are the official names of this protein?
Protein trichome birefringence-like 36.
What is the protein family that this protein belongs to?
Belongs to the PC-esterase family. TBL subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: Y1936_LACLM
Sequence: MFTQKSFEIFSIDGLEARMAEIRSEIQPVFSEIGQKLLTELSAKISNQEFYFHIAQHRRRTANAPENTWSAISTKARGYKMEAHFQLGIWEDYVFIYLSMIDQPKKQKEYAELLTNLSVEKMLTEDFIISKDHTKAEVFPLSAFSEAAERLGKVKKSELEIGRLWPKERFDGKEDSKILAEMLETIDQLLPIYQKLMEV
What are the official names of this protein?
UPF0637 protein llmg_1936.
What is the protein family that this protein belongs to?
Belongs to the UPF0637 family.
Protein: SECA2_MYCTO
Sequence: MNVHGCPRIAACRCTDTHPRGRPAFAYRWFVPKTTRAQPGRLSSRFWRLLGASTEKNRSRSLADVTASAEYDKEAADLSDEKLRKAAGLLNLDDLAESADIPQFLAIAREAAERRTGLRPFDVQLLGALRMLAGDVIEMATGEGKTLAGAIAAAGYALAGRHVHVVTINDYLARRDAEWMGPLLDAMGLTVGWITADSTPDERRTAYDRDVTYASVNEIGFDVLRDQLVTDVNDLVSPNPDVALIDEADSVLVDEALVPLVLAGTTHRETPRLEIIRLVAELVGDKDADEYFATDSDNRNVHLTEHGARKVEKALGGIDLYSEEHVGTTLTEVNVALHAHVLLQRDVHYIVRDDAVHLINASRGRIAQLQRWPDGLQAAVEAKEGIETTETGEVLDTITVQALINRYATVCGMTGTALAAGEQLRQFYQLGVSPIPPNKPNIREDEADRVYITTAAKNDGIVEHITEVHQRGQPVLVGTRDVAESEELHERLVRRGVPAVVLNAKNDAEEARVIAEAGKYGAVTVSTQMAGRGTDIRLGGSDEADHDRVAELGGLHVVGTGRHHTERLDNQLRGRAGRQGDPGSSVFFSSWEDDVVAANLDHNKLPMATDENGRIVSPRTGSLLDHAQRVAEGRLLDVHANTWRYNQLIAQQRAIIVERRNTLLRTVTAREELAELAPKRYEELSDKVSEERLETICRQIMLYHLDRGWADHLAYLADIRESIHLRALGRQNPLDEFHRMAVDAFASLAADAIEAAQQTFETANVLDHEPGLDLSKLARPTSTWTYMVNDNPLSDDTLSALSLPGVFR
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 2.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: C4S2C_XENLA
Sequence: MTEFLFCFSCCIGEQPQPKRRRRIDRSMIGEPMNFVHTAHVGSGDANTGFAMGGSFQDQMKSKGGYTPGISEVAL
What is the function of this protein?
Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly.
What are the official names of this protein?
CDC42 small effector protein 2-C.
What is the protein family that this protein belongs to?
Belongs to the CDC42SE/SPEC family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell membrane; Lipid-anchor.
Protein: SERC_KLEP3
Sequence: MAQVYNFSSGPAMLPAEVLKLAQQELCDWHGLGTSVMEISHRGKEFIQVAEEAEQDFRSLLNIPSNYKVLFCHGGGRGQFAGIPLNILGDKNVADYVDAGYWAASAVKEAKKYCAPNVIDAKITVDGKRAVTPMSEWQLTPGAAYLHYCPNETIDGIAIDDTPNFGDDVIVAADFSSTILSREIDVNRFGVIYAGAQKNIGPAGLTLVIVREDLLGKASVACPSILDYTVLSENDSMFNTPPTFAWYLAGLVFKWLKQQGGVAAMDKINQQKAELLYGVIDNSGFYRNDVAQANRSRMNVPFQLADSALDKLFLEESFAAGLHALKGHRVVGGMRASIYNAMPLDGVKALTDFMLDFERRHG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 36011_ASFM2
Sequence: MLPSLQSLTKKVLAKQCVPVDQYHVLKCCGLWWYDGPITFYVYRHKMFIRSTCFSEGIELNTVLMKAAKENNHDLIRLFAEWGADINYGLICAHTEHTRNLCRELGAKDRLDRDYILKIFFDTTRNKTDSNIILCHEMFSNNPNLKNVDNLDLREEIMWELRGLMEITYMLDHDNSFSNMLTKYWYAIAVDYGLKKAIHYFYQRYTHLHHWRLMCALFYNNVFDLHELYVIERVRMDIDEMMHIACVQDYSYAAIYYCFIMGANINQAMLVSIQNYNLGNMFFCIDLGANAFEEGKALAEQKENYLIADALSLKHYNPVISLLSVIMDPEKINCMLKNYHSINMRVFLDYERR
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.  In addition, inhibits the phosphorylation of host TBK1 and IRF7 and thereby negatively regulates the host cGAS signaling pathway and antagonizes IFN-mediated antiviral activity.
What are the official names of this protein?
Protein MGF 360-11L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 360 family.
Protein: YBCM_ECOLI
Sequence: MLARGKTNLKIEEIRMHKHHEIHRVKPLMPALCRIRQGKKVINWETHTLTVDNNQIILFPCGYEFYIENYPEAGLYLAEMLYLPIDLIESFQKLYTVTDQIRNKTSFFLPQNPELIYCWEQLKTSVSRGFSTKIQEHLAMGVLLSLGVNHVNHLLLSYSKQSLISRCYNLLLSEPGTKWTANKVARYLYISVSTLHRRLASEGVSFQSILDDVRLNNALSAIQTTVKPISEIARENGYKCPSRFTERFHNRFNITPREIRKASRE
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator YbcM.
Protein: RS11_LATSS
Sequence: MANKKNAPRKRRVKKNIEAGVAHIHSTFNNTLVMITDPNGNAVAWSSAGSLGFKGSRKSTPFAAQMAAEAAGKEAMEHGMKSIEVAVKGPGSGREAAIRSLQATGLEVTAIRDVTPVPHNGSRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: CRCB2_STRCO
Sequence: MNWLLVVAGGMIGAPLRYLTDRAVQSRHDSVFPWGTFTVNVIGSVVLGLLTGAALAGAVGSDLRLLLGTGLCGALTTYSTFSYETLRLTETGARLHAAVNVGGSVAAGLVAAFAGVTLADALWA
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 2.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NADA_DESAP
Sequence: MDISDELVAEINELRRRRKAIILSHYYQRPEVQDIADFVGDSLQLSRTAAATEAEVIVFCGVHFMAETAAILSPYKTVVLPDLRAGCPMADMAEVESLRSKKAELGDPVVVSYVNTTADVKAESDICCTSANVVRVIESISPDRRILFVPDRNLGAYAARQTGRELVLWPGFCCVHDDILPEHILRAKRKHPEALVVVHPECRPDVIDLADKVASTSGMVQFVRDSSFREFIIGTEEGITHQMGKLCPGKKFYLPSRGMVCGSMKLITLTKVRDALKRLEPRITVPEHIRYRALQSLERMLAL
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YR519_MIMIV
Sequence: MTYRSCIPQNDLECYYNPNKTKYKSTNILSSIQHKIDKELTAYITDKTIDDTFGNRMIVFRDSFYDKPKNSKIFRQIIHMIETSNCWYSVKFLMDNGISSLFSLGITPHHTYPKKYYPMIISPILSLESKNDYQDYLALVRLKNFIGYSYDYITKYWNYKLSNKQNFINDVMEMESQLSLVTLTIEQQNNPFVIYNSLKWREFLEKYDVDNFWSSILGSYLKKEDYVIFDNIQYLSYLREYLKNTSKNSIKNYLVYSLVKKFGLYTDLLEFYNDIVIESINHDQIFLNMFSQYFGIYLETVFETRYHDKDKKEYITKMFYDMKLYLRNYFIECKFTDKTKREISLKIDNLHMVIGRQNYQYDLENFPLMGNDFYENVLNLERYYFHESIKLIGSTINKEWFSINGGMYSFEVNAYYDPICNVLYIPTSIINDMTISLERDDVYNYGSIGTILAHEIMHSLDNFGLQVNCDLSIGNKWDISDYKFYLSDLRKIIQHRIKLSNYDIASSIDALSEDISDTLGLKLSFKTYLSKFNKKIEPDNLSTNDKIHLQKFFYSWTETFKNINNNNQDDHSPSYIRINAPLAHLDEFYYLYGVESQHLNYLDPQLRSRILDKIN
What are the official names of this protein?
Putative zinc metalloproteinase R519.
What is the protein family that this protein belongs to?
Belongs to the peptidase M13 family.
Protein: TRPC_CAMJE
Sequence: MILDKIFEKTKEDLKERKLKLPYDMLGRSLASNPFFPKDVIKALKRVEKEVKIIAEVKKASPSKGVIREDFDPLSIALNYEKNKAAAISVLTEPHFFKGSLEYLSLIRRYTQIPLLRKDFIFDEYQILEALVYGADFVLLIAKMLSMKELKKLLEFARHLGLEALVEIHDKEDLSKAIFAGADIIGINHRNLEDFTMDMSLCEKLIPQIPNSKIIIAESGLENKEFLEHLQNLGVDAFLIGEYFMREKDEGKALKALL
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: MAT2B_HUMAN
Sequence: MVGREKELSIHFVPGSCRLVEEEVNIPNRRVLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRARPKFEQVNLLDSNAVHHIIHDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAKEAAAVGAFLIYISSDYVFDGTNPPYREEDIPAPLNLYGKTKLDGEKAVLENNLGAAVLRIPILYGEVEKLEESAVTVMFDKVQFSNKSANMDHWQQRFPTHVKDVATVCRQLAEKRMLDPSIKGTFHWSGNEQMTKYEMACAIADAFNLPSSHLRPITDSPVLGAQRPRNAQLDCSKLETLGIGQRTPFRIGIKESLWPFLIDKRWRQTVFH
What is the function of this protein?
Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP.  Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine (PubMed:10644686, PubMed:23189196, PubMed:25075345).  Can bind NADP (in vitro) (PubMed:23189196, PubMed:23425511).
What are the official names of this protein?
Methionine adenosyltransferase 2 subunit beta, Methionine adenosyltransferase II beta, MAT II beta, Putative dTDP-4-keto-6-deoxy-D-glucose 4-reductase.
What is the protein family that this protein belongs to?
Belongs to the dTDP-4-dehydrorhamnose reductase family. MAT2B subfamily.
Protein: PROQ_YERPG
Sequence: MENQPKLNSSKEVIAFLAERFPLCFTAEGEARPLKIGIFQDLVERVQGEENLSKTQLRSALRLYTSSWRYLYGVKVGAERVDLDGNPCGVLEEQHVEHARKQLEEAKARVQAQRAEQQAKKREAAIAAGETPEPRRPRPAGKKPAPRREAGAAPENRKPRQSPRPQQVRPPRPQVEENQPRPVPVTDISKLQIGQEIKVRAGKSAMDATVLEIAKDGVRVQLSSGLAMIVRAEHLQF
What is the function of this protein?
RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities.  May regulate ProP activity through an RNA-based, post-transcriptional mechanism.
What are the official names of this protein?
RNA chaperone ProQ.
What is the protein family that this protein belongs to?
Belongs to the ProQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRS_GALME
Sequence: LKDGPCPSYMDTCCLSPDRR
What is the function of this protein?
Binds the A. niger cell wall component alpha-1,3-glucan, a fungal pathogen-associated molecular pattern (PAMP) that activates the host immune response.
What are the official names of this protein?
Putative serine protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted in the hemolymph.
Protein: RECR_TREPA
Sequence: MIPAIEEVVEHLSRLPGIGVKLATRLAYHLLKRDPAEAQVLARGIACLHERVYRCVCCGAFCEGRTCALCTDASRDRGIICVVERAQDVEMMAGVGEYRGLFHVLGGVIAPLEGVGPDQLRIAALLKRLQESSVREVILALNPTVEGDTTALYVQKILANFPVIVTRLASGIPVGGDLEYIDRTTLAHSLRGRRPLDCSEA
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: HIS8_CAMJJ
Sequence: MKFNEFLNHLSNYEPGKDIEVIAKEYGVKEVIKLASNENPFGTPPKAIECLRQNANKAHLYPDDSMIELKSTLAQKYKVQNENIIIGAGSDQVIEFAIHAKLNSKNAFLQAGVTFAMYEIYAKQCGAKCYKTQSITHDLNEFKKLYEAHKDEIKLIFLCLPNNPLGECLDASEVTKFIKGVDEDCLVVIDAAYNEFASFKDSKKHLEPCELIKEFDNVLYLGTFSKLYGLGGLRIGYGIANANIISAFYKLRAPFNVSNLALKAAVAAINDDEFAKKTLENNFSQMELYKEFAKKYDIKIIDSYTNFITYFFDEKNSTDLSEKLLKKGIIIRNLKSYGLNAIRITIGTSYENEKFFTEFDKILR
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: HIS4_RHOPT
Sequence: MILFPAIDLKNGQCVRLEQGDMARATVFNLDPAAQAQSFAAQGFQYLHVVDLDGAFAGKPMNAQAVEAMLKVVSMPVQLGGGIRDLKTIEAWLSKGIARVIIGTAAVRDPALVKEAAKAFPGRVAVGLDARDGNVAVEGWAESSQVTALDIAQRFEDAGVAAIIFTDIARDGLLKGINWDATIALAEAISIPVIASGGLASIEDVRTLLSPRAKKLEGAIAGRALYDGRLDPTEALALIGAAKAA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU4C_PHAVU
Sequence: MNDFPWLTTVVVLPIVGGSLIVLFPHKGNKTIKWYTYCICFIDLLLIAYVFCYHFELDDPLIQLTENYKWIHFFDFYWRFGIDGLSLGPILLTGFITTLATLSAQPVTRESKLFYFLMLAMYSGQLGTFSSRDILLFFIMWELELIPVYLLLSMWGGKKRLYSATKFILYTAGSSVFLLLGILGMSLYSSNEPTLNFESLTNQSYPVALEIIFYMGFLIAFAVKSPIIPLHTWLPDTHGEAHYSTCMLLAGILLKMGAYGLVRINMELLSRAHSIFCPWLMLLGSIQIIYAASTSLGQRNVKKRIAYSSVSHMGFLILGIGSISETGLNGAILQIISHGFIGAALFFLAGTSYDRLRLLYLDEMGGMAIPMPKIFTIFTTLSMASLALPGMSGFVAELIVLLGIITNQKYLLITKILITFVTAIGMILTPIYSLSILRQMFYGYKLFNTPNSYFFDSGPRELFISISILIPVISIGIYPDFIFSFSADKVEAILSNFL
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase chain 4, chloroplastic, NAD(P)H dehydrogenase, chain 4, NADH-plastoquinone oxidoreductase chain 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: FIBB_HUMAN
Sequence: MKRMVSWSFHKLKTMKHLLLLLLCVFLVKSQGVNDNEEGFFSARGHRPLDKKREEAPSLRPAPPPISGGGYRARPAKAAATQKKVERKAPDAGGCLHADPDLGVLCPTGCQLQEALLQQERPIRNSVDELNNNVEAVSQTSSSSFQYMYLLKDLWQKRQKQVKDNENVVNEYSSELEKHQLYIDETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRPFFPQQ
What is the function of this protein?
Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix.  Fibrin has a major function in hemostasis as one of the primary components of blood clots.  In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization.  Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood.  However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo.  Enhances expression of SELP in activated platelets.  Maternal fibrinogen is essential for successful pregnancy.  Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage.  May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.
What are the official names of this protein?
Fibrinogen beta chain.
What are the subcellular locations of this protein?
Secreted.