PharMolix/UniProtQA huggingface dataset:
Protein: RL15_HAMD5
Sequence: MRLNTLSPAQGAKQAPKRVGRGIGSGLGKTGGRGHKGQNSRTGGGVRRGFEGGQMPLYRRLPKFGFISRKAMVTAEVRLFQLALLETDVVDINILKACKIIPYQSQYAKIILSGTIEIPVIIRGLGVTKGARAAIEAAGGKIEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: NUOB_ECO5E
Sequence: MDYTLTRIDPNGENDRYPLQKQEIVTDPLEQEVNKNVFMGKLNDMVNWGRKNSIWPYNFGLSCCYVEMVTSFTAVHDVARFGAEVLRASPRQADLMVVAGTCFTKMAPVIQRLYDQMLEPKWVISMGACANSGGMYDIYSVVQGVDKFIPVDVYIPGCPPRPEAYMQALMLLQESIGKERRPLSWVVGDQGVYRANMQSERERKRGERIAVTNLRTPDEI
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ACPS_OLEA2
Sequence: MILGTGLDLTELGRIRAALERQPERFPRRILHDSELAAMPRLSVAWLAARFAAKEAAAKALGTGFTGGVAFRDIEVYKELSGKPCLRFHGAAFEHAQKMGVKKIHLSLTHGRDTAAAVVILEG
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TLR6_BOVIN
Sequence: MIKDKESPIRSCHFVYIVALVFGTIIQFSDESEFVVDMSKTSLIHVPKDLPPKTKVLDLSQNNISELHLSDISFLSGLRVLRLSHNRIQGLDISIFKFNHDLEYLDLSHNQLQKISCHPITTTLKHLDLSFNDFDALPICKEFGNLTQLNFLGLSATKLQQLDLLPIAHLHLSCILLDLEDYMKENKKESLQILNTKKLHLVFHPNSFFSVQVDISANSLGCLQLTNIKLNDYNCQVLLKFLSGLTGGPTLLNFTLNHVETTWKCLVKVFQFLWPKPIEYLNIYNLTIVESIDEEVFTYYKTTLKALKIEHITNKVFIFSQTALYTVFSEMNILMLTISDTRFIHMLCPQEPSTFKFLNFTQNSFTDSVFQNCDTLARLETLILQKNELKDLFKTSLMTKDMLSLETLDVSWNSLEYDRSNGNCSWVGSIVVLNLSSNALTDSVFRCLPPRIKVLDLHNNRIRSIPKDVTGLETLQELNLASNSLAHLPGCGIFSSLSILIIEHNSISNPSADFFQSCQKIRSLKAGNNPFQCSCELRDFIQSVGQVSSDVVEGWPESYKCDYPESYKGTPLKDFQVSELSCNTALLIITIVVPGLVLAVAVTVLCIYLDLPWYLRMVCQWTQTRRRARNVPLEELQRTLQFHAFISYSEHDSAWVKNELIPNLEKEDIRICLHERNFVAGKSIVENIINCIEKSYKSIFVLSPNFVQSEWCHYELYFAHHNLFHEGSDNLILILLDPIPQYSIPSSYHKLRALMAQRTYLEWPKEKSKHGLFWANLRASINIKLMEKAAEIH
What is the function of this protein?
Participates in the innate immune response to Gram-positive bacteria and fungi.  Specifically recognizes diacylated and, to a lesser extent, triacylated lipopeptides.  In response to diacylated lipopeptides, forms the activation cluster TLR2:TLR6:CD14:CD36, this cluster triggers signaling from the cell surface and subsequently is targeted to the Golgi in a lipid-raft dependent pathway.  Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.  Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B. burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2.  In complex with TLR4, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42.  In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to CD36.  This event induces the formation of a heterodimer of TLR4 and TLR6, which is rapidly internalized and triggers inflammatory response, leading to the NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion.
What are the official names of this protein?
Toll-like receptor 6.
What is the protein family that this protein belongs to?
Belongs to the Toll-like receptor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, phagosome membrane; Single-pass type I membrane protein. Membrane raft. Golgi apparatus. Note=Upon complex formation with CD36 and TLR4, internalized through dynamin-dependent endocytosis. Does not reside in lipid rafts before stimulation but accumulates increasingly in the raft upon the presence of the microbial ligand. In response to diacylated lipoproteins, TLR2:TLR6 heterodimers are recruited in lipid rafts, this recruitment determine the intracellular targeting to the Golgi apparatus.
Protein: VATF_SCHPO
Sequence: MSSQSYRERTLVSVIGDDDTVTGMLLAGTGQVNENGDKNFFIITQKTTDEQIAEAFDDYTTKRKDIAIVLINQFAAERIRDRIENHVQAFPAVLEIPSKDDPYDPEKDSILRRVRKIIGE
What is the function of this protein?
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit F, V-ATPase subunit F, Vacuolar proton pump subunit F.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase F subunit family.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: F8MT1_OCIBA
Sequence: MPSSSGVDSTQELLDAQAHIWNHIFNHINSMTLKWAVQLGIPDIIHKHDKPMTLSQLADAIPINRAKSDALHRIMRILVHSKFFDRVRTLPNEEEAYCLTRASRLLLRDEPLSLTPFALAVLDEDLMGTFHCVPEWFGNECPSPLEFKHEKSIREFAENNQRWSLLFNEGMANDARLVGSILAKESRKVFEGLETMVDVGGGTGMVSKAIVDAFPGMKGIVLDLPYVVSGLKGSGNLRYVGGDMFHSVPPADAVFLKWILHNWSDDECIKILEKCKEAITTSKNMKGGKVIIVDMILGYEKQQDEAVETQLFFDMMMMTTLTGKERTEQEWAKIFFAAGFKTYKIYPLLGLRSLIEVFP
What is the function of this protein?
Cation-independent flavonoid 8-O-methyltransferase involved in the biosynthesis of polymethoxylated flavonoids natural products such as nevadensin and salvigenin, aroma compounds which contribute to the flavor of sweet basil, and exhibit pharmacological activities such as anti-allergic, anti-oxidant, antibacterial, anti-proliferative, and anti-inflammatory effects (PubMed:23747095).  Catalyzes S-adenosylmethionine-dependent regioselective 8-O-methylation of flavonoids; mediates likely the conversion of pilosin (PIL) to nevadensin (NEV) and of 8-hydroxysalvigenin (8-OH-SALV) to gardenin B (GARD B) (PubMed:23747095).  Can also use 3',4',7,8-tetrahydroxyflavone as substrate (PubMed:23747095).  Accepts other unnatural O-diphenols including 7,8,4'-trihydroxy-flavone and 7-O-methyl-8-hydroxy-flavone, and, with a lower efficiency, 7,8-dihydroxy-flavone, as substrates (PubMed:23747095).
What are the official names of this protein?
Flavonoid 8-O-methyltransferase 1, ObF8OMT-1, 8-hydroxysalvigenin 8-O-methyltransferase, Pilosin 8-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.
Protein: SYV_STAAR
Sequence: MEMKPKYDPREVEAGRYEEWVKNGYFKPSEDKSKETYTIVIPPPNVTGKLHLGHAWDTTLQDIITRMKRMQGYDTLYLPGMDHAGIATQAKVEAKLNEQGITRYDLGREKFLEQAWDWKEEYASFIRAQWAKLGLGLDYSRERFTLDEGLSKAVKKVFVDLYNKGIIYRGERIINWDPKARTALSDIEVIHEDVQGAFYHFKYPYADVEGFIEIATTRPETMLGDTAIVVNPNDERYKDVIGKTVILPIVGRELPILADEYVDIDFGSGAMKVTPAHDPNDFEIGQRHQLENIIVMDENGKMNNKAGKYEGMDRFDCRKQLVEDLKEQDLVIKIEDHVHSVGHSERSGAVVEPYLSTQWFVRMEDLAKRSLDNQKTDDRIDFYPQRFEHTFNQWMENIRDWTISRQLWWGHQIPAWYHKETGEIYVGEEAPTDIENWQQDEDVLDTWFSSALWPFSTLGWPDLESEDFKRYYPTNALVTGYDIIFFWVARMIFQGLEFTDRRPFNDVLLHGLVRAEDGRKMSKSLGNGVDPMDVIDEYGADSLRYFLATGSSPGHDLRYSTEKVESVWNFINKIWNGARFSLMNIGEDFKVEDIDLSGNLSLADKWILTRLNETIATVTDLSDKYEFGEVGRALYNFIWDDFCDWYIEMSKIPMNGNDEEQKQVTRSVLSYTLDNIMRMLHPFMPFVTEKIWQSLPHEGETIVKASWPEVRESLIFEESKQTMQQLVEIIKSVRQSRVEVNTPLSKEIPILIQAKDKEIETTLSQNKDYLIKFCNPSTLNISTDVEIPEKAMTSVVIAGKVVLPLEGLIDMDKEISRLEKELAKLQSELDRVDKKLSNENFVSKAPEKVINEEKRKKQDYQEKYDGVKARIEQLKA
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YK1_MDBVW
Sequence: MTSSSSPSSSSSKCSNGASVCFIPKEWNDYPTSTLECVLTTDIKEHMKNYNEVVGAPISVGGVSAKLEFFGPNIWMRKDGDEKSKPNSKDYASRPIRDHSKI
What are the official names of this protein?
Uncharacterized protein K1.
Protein: RL21_EHRRG
Sequence: MFAIIETGGKQYKVKEHDIIRIEKLNASVGEEVTLSKVIALTGVDNEVIFTQNASVTASVLEQCRNDKVIIFKKKRRKNYRRKNGHRQYMTVLRITKINNME
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: HUTI_CERS1
Sequence: MMILGNLRVATLSDGYGLIPDAAILIEGGRIQWVGPEAHLPPSAAPRHDMGGRLCTPALIDCHTHAVFAGTRAAEFEMRLKGASYAEVAAAGGGIVSTVTATRAASADELLAASLPRIDAMLAGGVGTVEIKSGYGLDIETELRMLRVARRIGELRKVRVRTSFLGAHAVPPDYRGRPDAYLAEVVLPALKVAQDEGLVDAVDGFCEGIAFSPAQIAHLFAQAHKLRLPVKLHAEQLSNLGGAALAARHDALSADHLEYLDAEGVAALAAAGTVAVLLPGAFYALRETQAPPVAALRAAGVPMAVATDLNPGTSPLGALGLAMNMACTLFRLTPEEALAGTTIHAARALGLSDTGRIAPGFRADLAIWEAEHPAELSWRIGPAPLHARLHEGEFV
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_SALPA
Sequence: MLIKLLTKVFGSRNDRTLRRMRKAVSLINAMEPEMEKLSDDELKAKTNEFRARIEKGESVESLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNDRCIAEMRTGEGKTLTATLPAYLNALSGKGVHVVTVNDYLAQRDAENNRPLFEFLGMSVGINLPGMPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKKVNKIIPHLIRQEKEDSDTFQGEGHFSVDEKARQVNLTERGLVLIEELLVQEGIMDEGESLYSPGNIMLMHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEGVEIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIRKDLPDLVYMTEAEKIQAIIEDIKERTANGQPVLVGTISIEKSEVVSRELTKAGIKHNVLNAKFHANEAGIVAQAGYPAAVTIATNMAGRGTDIMLGGSWQAEVAALEAPTEEQIAQIKADWQVRHDAVLAAGGLHIIGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYTQRNELLDVSDVSDTINSIREDVFKATIDAYIPPQSLEEMWDILGLQERLKNDFDLEMPIAEWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKDPKQEYKRESFAMFAAMLESLKYEVISTLSKVQVRMPEEVEAMEMQRREEAERLAQMQQLSHQDDDAAVAADLAAQTGERKIGRNDPCPCGSGKKYKQCHGRLS
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: DLTC_STRSV
Sequence: MDIKAEVIEIIEELFMEDVSDMMDEDLFDAGVLDSMGTVELIVELENRFDIRVPVSEFGRDDWNTANKIVEGVTELRNA
What is the function of this protein?
Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA).  The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA.  The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanyl carrier protein, DCP, D-alanine--poly(phosphoribitol) ligase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the DltC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: M2_I57A5
Sequence: MSLLTEVETPIRNEWGCRCNDSSDPLVVAASIIGILHLILWILDRLFFKCIYRFFKHGLKRGPSTEGVPESMREEYRKEQQSAVDADDSHFVSIELE
What is the function of this protein?
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry.  After attaching to the cell surface, the virion enters the cell by endocytosis.  Acidification of the endosome triggers M2 ion channel activity.  The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur.  Also plays a role in viral proteins secretory pathway.  Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation.
What are the official names of this protein?
Matrix protein 2, Proton channel protein M2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses matrix protein M2 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type III membrane protein. Note=Abundantly expressed at the apical plasma membrane in infected polarized epithelial cells, in close proximity to budding and assembled virions. Minor component of virions (only 16-20 molecules/virion).
Protein: MBLC1_HUMAN
Sequence: MRTEPLCGASPLLVPGDPYSVVVLLQGYAEPEGVGDAVRADGSVTLVLPQTRGPASSHRESPRGSGGAEAALEEAARGPILVDTGGPWAREALLGALAGQGVAPGDVTLVVGTHGHSDHIGNLGLFPGAALLVSHDFCLPGGRYLPHGLGEGQPLRLGPGLEVWATPGHGGQRDVSVVVAGTALGTVVVAGDVFERDGDEDSWQALSEDPAAQERSRKRVLVVADVVVPGHGPPFRVLREASQPETEGGGNSQQEPVVGDEEPALH
What is the function of this protein?
Endoribonuclease that catalyzes the hydrolysis of histone-coding pre-mRNA 3'-end.  Involved in histone pre-mRNA processing during the S-phase of the cell cycle, which is required for entering/progressing through S-phase (PubMed:30507380).  Cleaves histone pre-mRNA at a major and a minor cleavage site after the 5'-ACCCA-3' and the 5'-ACCCACA-3' sequence, respectively, and located downstream of the stem-loop (PubMed:30507380).  May require the presence of the HDE element located at the histone pre-RNA 3'-end to avoid non-specific cleavage (PubMed:30507380).
What are the official names of this protein?
Metallo-beta-lactamase domain-containing protein 1, Endoribonuclease MBLAC1.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Note=Localizes in the nucleus during early S-phase of the cell cycle.
Protein: MUTS_PARMW
Sequence: MPGPSDDPTEIALQGNLFSDAEPTVSATGVEPSTACEAFSDMELTADAASRPRRRAPADHNAADHDSNTDESSDNSDDPAWAHHSQVDPQQLTPMLRHYVELKAAHPERVLLYRLGDFFECFFEDAITLSRLLELTLTGKEGGKAVGRVPMAGIPHHAAERYCGELIRRGFSVALCDQLETTPAKGALLKRDITRVLTPGTVLEEGMLSSRRNNWLAAVVIEPAHRDEPFRWGLASADVSTGEVQVMQRQDSDALHQQLAQLGAAELLSSTPESNPAWCPDQLRLTSVASTPFSRPAAEAALLRHYKLANLDGLGLPELPLALRAMGGLLAYLRDTQPLEENASVPLEVPAIVQRGDALVLDAQTRRNLELTATQRDGSLQGSLLWAIDRTLTAMGGRCLRRWLEAPLMDLDAIRQRQQLVSTLVEQRNLRQALRRLLRPMGDLERLAGRAGAGHAGARDLVAIADGLERLPQLAARLEGTIIRGPDWLDDLLQPDPALQDLASSIRHTLLESPPLSLSEGGLIHDGVDPLLDGLRNQLDDQDAWLSQQEKQERQRSGNSNLRLQYHRTFGYFLAVSKAKASAVPDHWIRRQTLANEERFITPALKEREGRIFQLRARACQREYELFCTLREQVGALAASIRRAARAVAGLDALTGLADTAASGAYCAPELVEGRALSLSEARHPVVEQLLVETRFTANDVHLGSGTDLVVLTGPNASGKSCYLRQIGLIQLLAQIGSWVPAAKARIGIADRIFTRVGAVDDLAAGQSTFMVEMAETANILHHATELSLVLLDEIGRGTATFDGLSIAWAVSEHLAGDLRARTVFATHYHELNNLANERANVANFQVLVEETGDDLLFLHRVSQGGASRSYGIEAARLAGVPTPVVQRARQVLDQIEAAA
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: YBC9_ENCCU
Sequence: MRSGGRCNSIENYEKVCRISSGSFGNVYRVRRKTDNRVFALKRMNPSMCYDTNGFSILYIREVMILKHIRHRNIMEIEEVVEGCEINDFFIVMECCDTDLRSVIHSVGKIGMKAARFLTCQMLKGLKFLHGAGIVHRDLKPSNILLMRDGGLRIADFGLARAIESQMTNLVVTLWYRPIEILLGSETYDESIDMWSVGCVVGEMLRGEPILAGEGEMDQLDRIFRLLGYPTDADFEGLDLPHFKNIRRPSTFEASFEGDFECYGEEAASFVRNLLSFDPRKRCTASQGLCSGFVADAEECPGELVDIVGRCTGDI
What is the function of this protein?
May play a role in the control of the eukaryotic cell cycle.
What are the official names of this protein?
Probable cell division protein kinase ECU11_1290.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS12_ECOHS
Sequence: MATVNQLVRKPRARKVAKSNVPALEACPQKRGVCTRVYTTTPKKPNSALRKVCRVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGALDCSGVKDRKQARSKYGVKRPKA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: UBIG_ECOSM
Sequence: MNTENLLKNNNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLRLGYIAERAGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTLNRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLGWVDQTSLKERHMTGLHYNPITNSFKLGPGVDVNYMLHTQNK
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-octaprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone-8 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: FUS3_ASPA1
Sequence: MPNARILKIQAAAALNNLTLDIPQPFAFGTANKSPEFLQKFPTGKVPAFESSDGEVTLVESDAIAQYVAASGPAAPALLGRNVAEQAAVRQWICFAENEVFRNMMAVVLWRVGMREYDAGVDGEGAKGLEEALAVVERHLAVGEKEFLATEGELSLVDLTLASALFWAFMHYIDEEMRGRFPRVVRWYLRVVGAERVREVFGEPSLVAVRKEASV
What are the official names of this protein?
Glutathione S-transferase-like protein.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily.
Protein: RL24_CHLT3
Sequence: MKLGIKKVKMHVKKNDMVKVISGNDKGVSGKILRVFPEKNRVIVEGVNMRKRHMRPTQEYPQGAILEREMPIHASNVKKVS
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: MURG_CLOPE
Sequence: MKKYKIIMTGGGSAGHVTPNLALVPKLKELGFEIKYIGSKNGIEKEIITKENIPYYSISSGKLRRYFDIKNFTDPFKVLKGVMDASRILSKEKPDVIFSKGGFVTVPVVIAASMKKIPVVSHESDLTPGLANKIASPFCDTLCVTFPESLKYIKDNKGELTGTPIREDLLKGDKERGRKFCNFKENKKVLMIIGGSLGSKVINESVRKILNEILKEYNVIHLCGKGNLDESLKNLDGYRQYEYISEELPDLMALADLVISRAGANTIFELLALRKLNILIPLSANASRGDQVLNANSFEKSGYSMVIKEEELNSELLLKSIKDLEKNREKYLNSMKMSKIGNGVNNIIDIIKKSAHM
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GATA_STAAE
Sequence: MSIRYESVENLLTLIKDKKIKPSDVVKDIYDAIEETDPTIKSFLALDKENAIKKAQELDELQAKDQMDGKLFGIPMGIKDNIITNGLETTCASKMLEGFVPIYESTVMEKLHNENAVLIGKLNMDEFAMGGSTETSYFKKTVNPFDHKAVPGGSSGGSAAAVAAGLVPFSLGSDTGGSIRQPAAYCGVVGMKPTYGRVSRFGLVAFASSLDQIGPLTRNVKDNAIVLEAISGADVNDSTSAPVDDVDFTSEIGKDIKGLKVALPKEYLGEGVADDVKEAVQNAVETLKSLGAVVEEVSLPNTKFGIPSYYVIASSEASSNLSRFDGIRYGYHSKEAHSLEELYKMSRSEGFGKEVKRRIFLGTFALSSGYYDAYYKKSQKVRTLIKNDFDKVFENYDVVVGPTAPTTAFNLGEEIDDPLTMYANDLLTTPVNLAGLPGISVPCGQSNGRPIGLQFIGKPFDEKTLYRVAYQYETQYNLHDVYEKL
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: RLF24_ARATH
Sequence: MSRSLALVYLSLLCLQTHLSISVTVPIPSVNGEIDAMLNRNGVIGEEEGEEMMPSEISRRVMMMRKQYISYETLRRDMVPCQKPGASYYACRSGQANAYNRGCSVITRCARDTNDIKT
What is the function of this protein?
Cell signaling peptide that may regulate plant stress, growth, and development.  Mediates a rapid alkalinization of extracellular space by mediating a transient increase in the cytoplasmic Ca(2+) concentration leading to a calcium-dependent signaling events through a cell surface receptor and a concomitant activation of some intracellular mitogen-activated protein kinases (By similarity).
What are the official names of this protein?
Protein RALF-like 24.
What is the protein family that this protein belongs to?
Belongs to the plant rapid alkalinization factor (RALF) family.
What are the subcellular locations of this protein?
Secreted.
Protein: CB5D1_XENLA
Sequence: MSPVRPRYFTPREVSRHCVLSDLWVSYLGRVYDLTPLLEQHKGDVLLKPIIAAGGRDISHWFNPKTGDVKTHIDPQTGCLKYYTPQGRFLHIAPCFPCSGWDNDFGRPWWKDTIYQVGILSSKTRFIRIINTLTSQEQMLEVCSEETIWEILQRYLAYNAHAASYTWKFCGVPLDMDKTLQENGVQDEDLEFEELKIDADLYTPSIHLYFNDDLTEL
What is the function of this protein?
Radial spoke stalk protein that binds heme under oxidizing conditions.  Required for the coordinated beating of multiple cilia maybe by functioning in a redox signaling pathway.
What are the official names of this protein?
Cytochrome b5 domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b5 family.