PharMolix/UniProtQA huggingface dataset:
Protein: APOE_TAPIN
Sequence: MKVLWAALVVTLLAGCQADVEREPEVQLGNEWAKWQAGQPWEQALGRFWNYLRWVQTLSDQVQEELLSTQATQELTVLIEETMKEVKTYKAELEQQLGPMAQETQARVSKELQAAQARLGADMEDVRNRLVQYRSELQAMMGQSTEELRGRLNSHLRKLRKRLLRDAEDLQKRLAVYQAGIREGAERSVNTLRERLGPLVEQAATVRSLVSKPLQERAEAWGQRLRGRLEKVGIQAGDRLDEVREQVQEVRAKVEEQANQMRLQAEAFHARLKSWFEPLVQDMQQRWAELVEKVQLAVGTSPTSESSEKQ
What is the function of this protein?
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids.  APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance.  Apolipoproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma.  As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL).  It also binds a wide range of cellular receptors including the LDL receptor/LDLR, the LDL receptor-related proteins LRP1, LRP2 and LRP8 and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles.  Finally, APOE has also a heparin-binding activity and binds heparan-sulfate proteoglycans on the surface of cells, a property that supports the capture and the receptor-mediated uptake of APOE-containing lipoproteins by cells.  A main function of APOE is to mediate lipoprotein clearance through the uptake of chylomicrons, VLDLs, and HDLs by hepatocytes.  APOE is also involved in the biosynthesis by the liver of VLDLs as well as their uptake by peripheral tissues ensuring the delivery of triglycerides and energy storage in muscle, heart and adipose tissues.  By participating in the lipoprotein-mediated distribution of lipids among tissues, APOE plays a critical role in plasma and tissues lipid homeostasis.  APOE is also involved in two steps of reverse cholesterol transport, the HDLs-mediated transport of cholesterol from peripheral tissues to the liver, and thereby plays an important role in cholesterol homeostasis.  First, it is functionally associated with ABCA1 in the biogenesis of HDLs in tissues.  Second, it is enriched in circulating HDLs and mediates their uptake by hepatocytes.  APOE also plays an important role in lipid transport in the central nervous system, regulating neuron survival and sprouting.
What are the official names of this protein?
Apolipoprotein E, Apo-E.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix. Note=In the plasma, APOE is associated with chylomicrons, chylomicrons remnants, VLDL, LDL and HDL lipoproteins. Lipid poor oligomeric APOE is associated with the extracellular matrix in a calcium- and heparan-sulfate proteoglycans- dependent manner. Lipidation induces the release from the extracellular matrix.
Protein: HFLD_SHEHH
Sequence: MSDQLFERTMAFAGILQAVAQVQYIARHGDSDKDALAASLQSVLVTNPETTSDVYADKVALRKGYELIVSQLGDAKQKDVEVTRYLVGILALERKLTRSSNAMGMLSERINQIHRQLSHFEITDEQVIANFAGIYSDIISELGPKLQISGNPEFLKRTQTQQKIRALLLSAMRSAVLWRQLGGKRRHLVFARKTIVDTAMKSLTL
What are the official names of this protein?
High frequency lysogenization protein HflD homolog.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HXUC1_HAEIN
Sequence: MRFSKLSLAITTTLVTANALAQSVELDSINVIATRDPSRFAYTPEKQSKDSLLSKQATSVADALEDIPNVDVRGGSRSIAQKPNIRGLSDNRVVQVIDGVRQNFDLAHRGSYFLPMSLIQEIEVIKGPSSSLWGSGALGGVVAMRTPNALDLLKNNDKFGVKIRQGYQTANNLSEKDVSVFAANDKFDVLISGFYNNADNLRTGKGNKLNNTAYKQFGGLAKFGWQINDANRVELSHRETRFKQTAPSNNEVENELTNEQITDQIKKFHGQKDDLLPPTTQPSPSERSEFYSKVKTRLGSVSYLTDQQIPDQSTVFNYYLTPDNPYLNTHIALYNNKTIEKEQRKVSGVKDQTKLTTRGINLRNSSELSHISFVYGVDYMRDKIRTERGTNGSDAKFRADPYNANSNTTGVYLIAHIPLFGEKLLVSPSVRYDHYDTSSKTVKYKDNHLSPATKLTWIVTNWLDFTAKYNEAFRAPSMQERFVSGAHFGANTLGLDHINRFVANPNLRPETAKNKEITANLHFDSLFKQGDKFKIEATYFRNDVKDFINLKIFNDAKTSASAGANPNTNGALLPKNSQYQNITNARLSGIELQAQYQTERLTLFTNYGSTKGKDKDSGEALSNIAASKIGVGVNYALVKDKFTVGATVTHYAAQRRVPKDHSVTYPSYILTDLRATYAPLKGEWKNLRLDFALENLFDRKYQPAFSLMEGTGRNAKISAVYSF
What is the function of this protein?
Required for utilization of free heme at low concentrations.
What are the official names of this protein?
Heme/hemopexin utilization protein C.
What is the protein family that this protein belongs to?
Belongs to the TonB-dependent receptor family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: CHAC_ECOLI
Sequence: MITRDFLMNADCKTAFGAIEESLLWSAEQRAASLAATLACRPDEGPVWIFGYGSLMWNPALEFTESCTGTLVGWHRAFCLRLTAGRGTAHQPGRMLALKEGGRTTGVAYRLPEETLEQELTLLWKREMITGCYLPTWCQLDLDDGRTVNAIVFIMDPRHPEYESDTRAQVIAPLIAAASGPLGTNAQYLFSLEQELIKLGMQDDGLNDLLVSVKKLLAENFPDGVLRPGFA
What is the function of this protein?
Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide.  Acts specifically on glutathione, but not on other gamma-glutamyl peptides.
What are the official names of this protein?
Glutathione-specific gamma-glutamylcyclotransferase, Gamma-GCG, Cation transport regulatory protein ChaC.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
Protein: HBB_HYDGR
Sequence: VHWSAEEKQLITGLWGKVDVAEVGGATLGKLLVVFPWTQRFFAHFGNLSSANAIICNPVVKAHGKKVLTSFGEAIKHLDSIKETFAKLSELHCEKLHVDPENFRLLGNILIIVLAGHHGKEFTPSTHAAFQKLVRAVAHSLARVYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RSMG_VIBCH
Sequence: MNPLRVKLDALISKTSLTVTEQQREQLVGYVQLLDKWNKAYNLTSVRDPMEMLVKHILDSLVVSPHLVGERFIDVGSGPGLPGIPLAIMHPDKEFVLIDSLGKRIRFLKQVIHDLKINNVLPVQSRVEEFDPESGFDGVLSRAFASMTDMVNWCQHLPKPNAGVFLALKGVRPDDEITLLPEWCSVTDIKALQVPELEGERHLVILSRKG
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C76L_ASFB7
Sequence: MDQEQLFDKLYSLNLQLTAKNDQKKRKPVFYPEWEKDPTDTNDDVYYGLRYKPEAKKTLRSTWMQSEFESHRSSSA
What are the official names of this protein?
Uncharacterized protein C76L.
Protein: APOC2_TUPGL
Sequence: MGTRFLLALFLVLLVLGLEVQADPESRQDEPASPALLAQMRESFSSYWDSAKAAAQDLYQKTYLPAVDERIRDMYSKSTAAVTTYAGIFTDQLFSMLKGEQ
What is the function of this protein?
Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma.  Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase.  Both proapolipoprotein C-II and apolipoprotein C-II can activate lipoprotein lipase.
What are the official names of this protein?
Apolipoprotein C-II, Apo-CII, ApoC-II, Apolipoprotein C2.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein C2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RF3_VIBVU
Sequence: MSNAPFLSEVSKRRTFAIISHPDAGKTTITEKVLLFGRAIQTAGTVKGRGSSQHAKSDWMEMEKERGISVTTSVMQFPYNDCLVNLLDTPGHEDFSEDTYRTLTAVDSCLMVIDAAKGVEDRTRKLMEVTRLRDTPIVTFMNKLDRDIRDPMELLDEVESELNIACAPVSWPIGCGKEFKGVYHIHRDETILYSTGQGHTIQEQRIIKGLDNPDLDAEVGADLAEQLREELELVLGASHEFDQEMFLKGELTPVFFGTALGNFGVDHMLDGLTDWAPAPLPRQANERAVEATEDKFTGFVFKIQANMDPKHRDRIAFMRIVSGTYTQGMKMNHVRLGKQVNISDAVTFMAGDRSRAEAAYAGDIIGLHNHGTIQIGDTFTQGESLKFSGIPNFAPELFRRIRLRDPLKQKQLLKGLVQLSEEGAVQVFRPLQNNDLIVGAVGVLQFDVVVARLKSEYNVEAIYESVNVATARWVECGDAKKLDEFQRKNQTNLALDGGDNLTYIAPTMVNLNLAKERFPEVEFRATREH
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARNB_PSEAB
Sequence: MSLDFLPFSRPSIGEDEIAAVEQVLRSGWITTGPKNQELEQRFAERLGCRHAVALSSATGALHVTLLALGIGPGDEVITPSLTWVSTANVITLLGATPVFVDVDRDTLMCSAQAVEAAIGPRTRAIVPVHYAGSTLDLEGLRTVAGRHGIALVEDAAHAVGSEYRGRPVGSRGTAIFSFHAIKNLTCAEGAMFVSDDSALAERVRRLKFHGLGVDAYDRLSHGRKPQAEVIEPGFKYNLADLNAALALVQLKRLDALNARRQALAERYLERLAGLPLAPLGLPAHKQRHAWHLFILRIDAEACGLGRDAFMEALKARGIGSGIHFIASHLHHYYRQRQPRLSLPNSEWNSARLCSIPLFPDMRDDDIERVARAIEDILEKRR
What is the function of this protein?
Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase, UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase, UDP-Ara4O aminotransferase, UDP-4-amino-4-deoxy-L-arabinose aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.
Protein: YCT9_YEAST
Sequence: MALSRSVGRGSKLTSPKNDTYLLASFRWNLDRDLLFRCERYFCMWASTGYSSSCSCFPATRSASVDSTPSVDSTGSTSDVVDDRGETSMDSCGRITLSYVTECRLLASAELSLRILRNSSSCNKSLVSVILAICFGALAASRAEQPPA
What are the official names of this protein?
Putative uncharacterized protein YCR049C.
Protein: RS17_THIDA
Sequence: MSEIKKVVRTLTGRVVSDKMNKTVTVLVERRVKHPVIGKVIRMSKKYHAHDENNECHEGDTVQIEESRKLSRTKAWTVSKLVERARV
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: LPXK_XANAC
Sequence: MSKRGTRTPGYWYDNTPIPLPARILAPVYGAAIALRRALYRRGWRRRHGVPVPVIVVGNVTAGGTGKTPLTIALVAKLQEAGWTPGVASRGYGRDDAGTARWVEADTPVALGGDEPVLIAWKTGARVRVDSDRLAAARALVEAGCDIVICDDGLQHYRLARDVEIEVVDGQRRYGNGRLLPAGPLREPAARAQDCDFRVVNLGQASATATPQAPDDAGFGKWQMRLSIDSVQPMDGKRAQPLSMLAGQRVHAVAGIAHPERFFAMLRARGIGVVPHAFADHHVYRAADFSFGSRLPVLMTEKDAVKCRPFADEWLYSVPLKAELPAAFWVSLLDRLNKLASRQGV
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: RL16_CUPNH
Sequence: MLQPKRRKYRKEQKGRNTGKATRGNAVSFGEFGLKAMGRGRLTARQIESARRAMTRHIKRGGRIWIRIFPDKPISKKPAEVRMGNGKGNPEYYVAEIQPGKMLYEMDGVSEDLAREAFRLAAAKLPIATNFVVRQVGT
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: TRUA_FRATM
Sequence: MKNYLLQIEYFGKNYCGWQRQSHSPSVQEELEKALSKIANQNIEVTCAGRTDTGVHATSQIVNFYSNADRPLSAWQRGVNALLPQDIKILAVQQVDNNFNSRFTAINRTYNYIIYNSATSSPIFAEHCLWENRELDIDKMNQACEYLLGEQDFSSFRSSQCQSNTPFRNIQKAEFIKQGSFIVFEVVGNAFLHHMIRNLVGSLLKVGLGFESPEWIKVVLEVKDRTQAAETAKAHGLYFVGVEYPEFSFKRQIIKLFC
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: BR1E_LITPI
Sequence: FLPIIASVAAKVFPKIFCAISKKC
What is the function of this protein?
Antibacterial activity against Gram-positive bacterium S. aureus and Gram-negative bacterium E. coli.  Has activity against C. albicans.
What are the official names of this protein?
Brevinin-1Pe.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
Protein: AKTP2_DROPE
Sequence: MWFSWNNTEQSIAVRQGYQVLAEYQLIEQEQLKNIYVIPSYASALHWFGVIFIHSGFYAGSMFRFSIILPDNFPNGTSLPTIIFTTTCYHPHIRPQTQSLDLAPFFTGWRKDHYHVWHLLKYIQAIFADPEGSISATVTPSGDRVCLEEAYNMDALAMLSNDRVAFIKKVQELALFTKKHMYDKPTSNDPHYIVIEPFCSERHTKIMEQLKSPSWKEATSMDTSPPAQCLARIDSSRQMDEEEAKQSAKLFAKNGKAAAALQ
What are the official names of this protein?
Protein crossbronx-like.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family. FTS subfamily.
Protein: RL2_SULIY
Sequence: MGKNLLQQRAGKGSPTFRSPSWLRIGKVRYPNIFGHLVGKVIDIVHNPGMNAPVAIIKLENGTKFLTQAIQGLVINQKIEFGKGSPIANGNVIEIGDAPEGTIVCNVEENFGDGGKYARSAGSYAVVVGKSGDKVLIKLPSDKIKAVSNKARATVGVVAGGGVVEKPLLKAGANYWKYKVKAKKWPIVRGVAMNVVDHPHGGGLHQSVSRPSTVSRNAPPGRKVGHIAARRTGRKEGK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: PYRD_ANAD2
Sequence: MLWPALRSVLFQLDPERVHHLAHWALHRVPLAVARARRPASIPALAVRCMGLDFDGPVGLAAGFDKGDVALPGLFGLGFSHVEIGTITPRPQPGNDRPRLFRLPEHRALLNRMGFNNEGMEACARRLAALPPAARLGPVGINVGKNKVTPNEDAAADYLACIERLHPYADYLVVNISSPNTPGLRQLQERDALDRLLRACVRHLAERAPGKPLLVKLAPDLSPEALDEAVDVAIAAGAAGIVATNTTLSRAGVERHPRAAEAGGLSGAPLERLATDVVRRCYARAAGRVPIVGVGGVMDAEGAYAKIRAGATLVQAYTGLIYGGPAFVGRVNAGLARLLERDGFSTLSDAVGADHRQGGGKAAG
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RF3_LEGPH
Sequence: MSDFYQDFNKRRTFAIISHPDAGKTTVTEKLLLFGGAIQLAGTVKGRKADRHATSDWMEMEKERGISITTSVMQFIHNQHVINLLDTPGHEDFSEDTYRTLTAVDSALMVIDVAKGVEERTVKLMEVCRLRDTPIMTFINKLDREGREPIDLLDEVESVLGIQCAPITWPVGMGKRFKGIYHRYQDIIYLYQQGSNAKKVEAMQIKGLDNPQLDELIGDSADELREEIELVKGASHEFNLEAYLAGKMTPVYFGSAINNFGIKELLDDFVEYAPGPQPRATQERVVSPHEETFSGFVFKIQANMDPKHRDRIAFVRVCSGSYKKGMKLNHLRIGKEVQISNALTFMAGDRSHTELALAGDIIGLHNHGTIRIGDTFTQGEHLKFTGIPNFAPELFRLVRLRDPLKSKALLKGLIELSEEGATQVFRPLNSNQLILGAVGILQFDVVAHRLKHEYKVDCIYESVNIACARWVYSEDDKAMSEFRTKAYDYLALDGGDMLMYLAPTKVNLTMAEERYPKIKFCATREH
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLY_METPP
Sequence: MSNDNQLDKKSQAWSALFSEPMSELVKRYTASVDFDQRLWRADIDGSLAHAEMLAAQGILTAEDHAAIVRGMAQVVAEIESGAFEWKLDLEDVHLNIEARLTQLVGDAGKRLHTGRSRNDQVATDVRLWLRGEIDAIGALLSALQRALVDVAEPNAEVILPGFTHLQVAQPVSFGHHLLAYVEMFARDAERLLDVRRRVNRLPLGAAALAGTSYPLDRERVARTLGFDGVCQNSLDAVSDRDFAIEFTAAASLCMVHVSRLSEELILWMSQSFGFIDLADRFCTGSSIMPQKKNPDVPELARGKTGRVVGHLMALITLMKGQPLAYNKDNQEDKEPLFDTVDTLKDTLRIFAELVGGISVKPEAMERAALKGYATATDLADYLVKKGLPFRDAHEVVAHAVKTAIAQGRDLSELPLPALQAFHPAITDDVHAALTLRGSLDARQVLGGTAPAQVRFQIARHRTRLGS
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHOSP_BDV1
Sequence: MATRPSSLVDSLEDEEDPQTLRRERSGSPRPRKIPRNALTQPVDQLLKDLRKNPSMISDPDQRTGREQLSNDELIKKLVTELAENSMIEAEEVRGTLGDISARIEAGFESLSALQVETIQTAQRCDHSDSIRILGENIKILDRSMKTMMETMKLMMEKVDLLYASTAVGTSAPMLPSHPAPPRIYPQLPSAPTADEWDIIP
What is the function of this protein?
Essential component of the RNA polymerase transcription and replication complex.  Acts as a scaffold which brings L in close proximity to the N-RNA complex.  Plays a role in the segregation of the viral genome in host daughter cells during mitosis by interacting with host HMGB1, a host chromatin-remodeling DNA architectural protein, thereby stabilizing RNP on chromosomes.  Interacts with host TBK1 and thus interferes with activation of cellular antiviral state.  Inhibits cellular histone acetyltransferase activities.
What are the official names of this protein?
Phosphoprotein, P protein, p23, p24.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=P subcellular localization is modulated by the interaction with protein X.
Protein: TRUA_CHLAA
Sequence: MRTIALLLAYDGTDFAGSQWQTDIRTVQGALESAWEALTQERRRIVLAGRTDAGVHATGQVAHVQTTTRHNLQTIWRGLNAHLPVDLAIQNVGEAVPDFHARFSAIQREYRYLIDCAAAPLPQLRHQVLHYAGTLDVAAMTAALKLLEGTHDFAAFTTATPAQRSTVRTMYWTRVGDYEWFERRLLAIEVAANAFLQHMVRMIVGTLLLVGRGRMTVDQFGEVLASRDRRLAGPTAPAHGLTLTAVRYPPGLIRWVEPSKRQNGTTKVEQPSSYVHEE
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: AIM9_CANDC
Sequence: MLSRVARYSRTLNQLTRTSQGGLLSAVLRTSIRQNSTDSPPSNSANEIYTKLSDTKDPQRNQFFQYTWGSWLTNDKSKKKQRETTFSIEGLTLFIDRINQLESKLGQPKSLEGAFVLTNNKELLGSTKEKVIVRSIASIHEGKHHRVYKITLNTGKDLVLRIPYKLDSDAAIASKLKSEVATIDFLKLKLGLNVPRVLAYGVDSNNELKSPFILQEFISGELLMKKWHPLLPDSEETNKNLHEVIDPIAQFQDKILSVTFKKFGSLYFHDDVEGSLQNDVPYEGETDSTLSNRWRIGPSVERQFTRNKSKLQQSIIDQYNGPWDASNTTALLESVADIELENAKSKLALINADAGANENDKVLITKQIKTFENLKKISPQLINDKSKSIMNVQELFKPRLYIPDLDPLNVIQHTESENYFIDFEGSTIKPFILTSYPKFVAYQGAKIYNLEEDVPGYKEMEELEKQQYDFMYYKTRNERMWELELNKYRHDLIAVASPHIKVLKSPYLQALDIKNGKDYLYVEGSIVQLQAMWEAYVANELVNSKDTKFPIEYTAEYLDQHQQELSDYQLETVSSPFSATGGWIPQDMFDTLKAQGILVETKDGDYKVETEKVLENPPSPSEEK
What are the official names of this protein?
Altered inheritance of mitochondria protein 9, mitochondrial, Found in mitochondrial proteome protein 29.
What is the protein family that this protein belongs to?
Belongs to the AIM9 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: KDGD_RHOOB
Sequence: MITASPQEIAHKLGSGLLSFPVTHFTDDHSFDEAAYRENIGWLGQFDASGLFAAGGTGEFFSLTPPEVEQVVRAAVQEAPDGLPVIAPAGYGTATAVQMARSAESAGAHGILLLPPYLTEASQDGLVAHVKEVCAATTLGVTIYSRANAVYTEAAVAELADSCPNLVGFKDGVGNIEQMTRIYASLGDRLTYVGGLPTAEMFALPYLALGVTTYSSAIYNFVPQFALDFYNALRSGDNAFVVNALNDFVIPYCNLRNKKQGYAVSIIKAGMKVIDRPAGPVRPPLTDLDAVELAELADLIKKVS
What are the official names of this protein?
Probable 5-dehydro-4-deoxyglucarate dehydratase, 5-keto-4-deoxy-glucarate dehydratase, KDGDH.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
Protein: RNFE_PSEA7
Sequence: MSEQGLREIARDGLWRNNPGLVQLLGLCPLLGTSNSTVNALGLGLATLLVLVCSNAAVSLVRGAVSEAIRLPAFVMIIAALTTCIELLMQAWTYELYQILGIFIPLITTNCVILGRAEAFAAKNGVLRASFDGLLTGLGFALVLLVLGGLRELLGQGTLLADMQLLFGPAAETWKIQIFPHYQGFLLAILPPGAFIMLGLLIALKNRIDESLAERARAQAGDVPASPQRQRVRVTGVIE
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit E, Rnf electron transport complex subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EFP_SHEON
Sequence: MKTAHEVRPGNVIMFEGSPWVVQKTETTRSGRNAAIVKLKLKNLLLNSGTETTFKGEDKIDDIILDRLDCTYSYFADPMYVFMDAEYNQYDVEAENLGDAAAYIVDGMEETCQVTFYDGKAISVEMPTTIVREVIYTEPSARGDTSGKVMKPATITGGGTISVADFVKVGDKIEIDTRTGEFKKRV
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAY_THENN
Sequence: MIAASFLLNLLIYPFLINLFRKKSVGQYIRKEGPDLHGYKEGTPTMGGILFVLIGLLFGVLSKENGVILTGAFLFFLIGFLDDFLSIAKKNSTGLRAYQKALLQIAAASVVIAFSQPETAVDFFGIKLEMGAWYYLLALIVIVGSSNAMNLTDGLDGLAGWVYISGAIPYWFFLKEKGFSENIIILLSAGVLAFLIFNSKPARIFMGDTGSIALGGTLGVVSVLTKTEFYLIVFFPILVVETLSVILQILSFKLFKRRIFRMAPLHHHFELLSWEEEKIVAVFTIFNLISSLIALEVFGVIG
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL18_BLOPB
Sequence: MNKKDARIKRAVKTRKKLYKLDAIRLVIHRTCRHIYAQIIAKDNSNVLVAASTTEKLISSQLTTTSNKKAAAIVGKIIAERAIKKGIINVSFDRSGFKYHGRVKMLADRARQTGLSF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RL10_RHORT
Sequence: MNREEKKELVSELNSLFGEASACVVTHYKGMTVAELEQLRKGMRAAGASFRVTKNRITRLALADTPFEGLADLFTGPTAIAISKDPVAPAKVCVEFAKKNEKLVILGGAMQGNVLDKQGIEALAKLPSLDELRGRLIGMITTPATRIAGVTQAPAAQLARVFNAYATKEEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.