PharMolix/UniProtQA huggingface dataset:
Protein: PSBH_SYNSC
Sequence: MAQRTRLGDLLRPLNSEYGKVVPGWGTTPVMGIFMVLFLVFLLVILQLYNKSLILEGINVNWNGLG
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein H, PSII-H.
What is the protein family that this protein belongs to?
Belongs to the PsbH family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: RHPN2_BOVIN
Sequence: MTDTLLPAAPQPLEKEGNCYFRKGCNPLAQTGRSKLQNQRAALNQQILKAMRMRTGAENLLKAATNQKVREQVRLELSFLNSDLQMLKEELEGLNISVGVYQNTEEAFTIPLIPLGLKETKDVDFSVALKDFILEHYSEDSYLYEDEIADLMDLRQACRTPSRNEAGVELLMSYFMQLGFVESRFFPPTRQMGILFTWYDSLTGVPVSQQNLLLEKASILFNIGALYTQIGTRCNRQTEAGLESTVDAFQRAAGVLNYLKETFTHTPSYDMSPAMLSVLVKMMLAQAQESTFEKVCLPGLQNEFFLLVKVAQEAAKVGEVYRQLHTAMNQEPVKENIPYSWASLACVKAHHYEALAHYFTATLLIDHQLKPGEDEDHQEKCLSQLYSHMPEGLTPLATLKNVHQRQLLGKSHLCQAVTHHEESMREASLCKKLRNIDVLQEVLSAAHDRSQLKYTQLREDDDLLNLTDAPDIVSKTEREVEIIVPQFSKVTVTDFFQKLGPLSVFSANKRWTAPRSIHFTAEEGDLGFTLRGNSPVQVHFLDPYCSAAAAGTKEGDYIVSIQDVDCKWLTLSEVMKMLKSFGQDDIEMKVVSLLDATSTMHSKCATYSVGMQKTYSMICLGIDVDDKTDKTKKVSKKLSFLSWGTNKNRQKSASTLCLPSVGVTMPPVKKKLSSPFSLLNTDSSLY
What is the function of this protein?
Binds specifically to GTP-Rho.  May function in a Rho pathway to limit stress fiber formation and/or increase the turnover of F-actin structures in the absence of high levels of RhoA activity (By similarity).
What are the official names of this protein?
Rhophilin-2, GTP-Rho-binding protein 2.
What is the protein family that this protein belongs to?
Belongs to the RHPN family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region.
Protein: PSBI_GLOVI
Sequence: MEVLKWVVTIVVLLFVAIFAFGFLSGDPSRNPGRGSGQ
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.4 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: YQGF_OCEIH
Sequence: MKIIGLDVGSKTIGVAVSDALGWTAQGVKTIRWDENDLSSADEELEKIISEHEIGKAIIGLPKNMNGTIGERGEASQRYANHIEKVFQIPVDLWDERLTTMAAERVLLEADMSRSKRKKVIDKMAAVMILQGYLDQK
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_VARPS
Sequence: MARLQQHYREKIAKDLTEKFGYKSPMQVPRLTKITLNMGVGEAVADKKVLDNAVADLTKIAGQKPVVTKSKKAIAGFKIRENQPIGCMVTLRGVQMYEFLDRFVTIALPRVRDFRGISGRAFDGRGNYNIGVKEQIIFPEIEYDKVDALRGLNISITTTAKTDEEAKALLAGFRFPFKN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: PLH9_FORAG
Sequence: MFVGSFTDKKPGTGIHVFDFNTKSGEAQLLSEVDSIINSSFLKLSPNGKYLYSVIESQLQTHGKIAAFKIDSNAGDLKLINMQDCGGRNPAHIEIDKSGKFLAVSNYTDPSLSFFEVDETGKIKKIDEFFTFTGSGIVKGNQDTAHIHSSNFSLENDYLFLQDLGSDCIHKFKVNLDANQNMSLQKADAIKVKPGSGPRHFVFHQNGKYGYGINELSGKVSAYALLNGNLKFLADYNAYSKKQDSYRSADIHISPDGKFLYASNRGPNEDSIVIFSINKSNGALKLIGHEPTYGEHPRNFAIDPSGQFLLVANQFSNNIVIFRRDVETGKLQKLPQELVVNGSSSLQMFTYSH
What is the function of this protein?
Carboxylic ester hydrolase that may be involved in ulvan degradation (Probable).  Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall.  It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl) (Probable).  Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate (By similarity).
What are the official names of this protein?
6-phosphogluconolactonase, P9_lactonase, Polysaccharide utilization locus H protein P9, PUL H protein P9.
What is the protein family that this protein belongs to?
Belongs to the cycloisomerase 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_SYNS3
Sequence: MSQLQTLRGMVDLLPEQTRRWQAVESVAREHFRCAGLDEIRTPLLEFTDLFARGIGEGTDVVGKEMYTFLDRGDRSCTLRPEGTASVVRAALQHGLLSQGAQRLWYGGPMFRYERPQAGRQRQFHQIGVEFLGASSPRSDAEVIALAWDLLTDLGIQGLNLEINSLGTPDDRQRFRSELVQWLEERVEQLDAESQARLTTNPLRILDSKDKGTQQLLNDAPTLLKALSKESVDRFEQVCALLTALQIPYQLNPRLVRGLDYYGHTAFEITSDQLGAQATVCGGGRYDGLIQQLGGPVTPAIGWALGMERLLLVISAAAQADPDGAAARLTATPSPLVYVINRGEQAEPQALSLARQWRGAGLAVELDGSSASFGKQFKRADRSGAPWAVVLGDEEASAGQVRLKPLRGEGEEKQLTWEDALSYLMKQR
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IDH2_YEAST
Sequence: MLRNTFFRNTSRRFLATVKQPSIGRYTGKPNPSTGKYTVSFIEGDGIGPEISKSVKKIFSAANVPIEWESCDVSPIFVNGLTTIPDPAVQSITKNLVALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTYENVDLVLIRENTEGEYSGIEHIVCPGVVQSIKLITRDASERVIRYAFEYARAIGRPRVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLNSGLSAGSLGLTPSANIGHKISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNHMGLTNHADQIQNAVLSTIASGPENRTGDLAGTATTSSFTEAVIKRL
What is the function of this protein?
Performs an essential role in the oxidative function of the citric acid cycle.  Also binds RNA; specifically to the 5'-untranslated leaders of mitochondrial mRNAs.
What are the official names of this protein?
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial, Isocitric dehydrogenase, NAD(+)-specific ICDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
Protein: DXR_PELTS
Sequence: MKNIVLIGSTGSIGRQTLEVIGSLPDRFKVVGLGSGKNWRLMAEQIRVFRPSAVAMAGEREIMNLKELLAGSYCPELGWGRTGMESLASMPEADLVVVAVTGFAGIYPTIAAIQAGKDVALANKETLVAAGHLVMKMAERHRAAILPVDSEHSAVWQCLCGRNSGEVEKIILTASGGPFREMCLEKLEKVTVDMALKHPNWNMGSKITIDSATLMNKGLEVIEAKWLFGLNYSQIEVVIHPQSIVHSAVEFLDGSVIAQMGLPDMRLPIQYALTYPERLPGSFPKLKLASLQGLTFEEPDTRRFPCLSLAFEAGLAGGTMPAVLNAANEVAVEFFLKGLLPFLGIPSVVRSVMEKHEMASDPGLEEIIEADRWARNMGVKVIRDLFN
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: CHIA_PHAAN
Sequence: MKPNMACLKQVSALLLPLLFISFFKPSHAGGISVYWGQNGNEGSLADACNTGNYKYVNIAFLFTFGGGQTPQLNLAGHCNPSINNCNVFSDQIKECQSKDIKVLLSLGGASGSYSLTSADDATQVANYIWNNFLGGQSSSRPLGDAILDGVDFDIESGTGEHWDDLARALKGFNSQLLLTAAPQCPIPDAHLDTAIKTGLFDIVWVQFYNNPPCQYSSGNTNDLISSWNQWTSSQAKQLFLGVPASTAAAGSGFIPADVLTSQVLPTIKGSSKYGGVMLWDRFNDGQSGYSGAIIGSV
What is the function of this protein?
This protein functions as a defense against chitin containing fungal pathogens.
What are the official names of this protein?
Acidic endochitinase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: T2R20_PANPA
Sequence: MMSFLHIVFSILVVVAFILGNFANGFIALINFIAWVKRQKISSADQIIAALAVSRVGLLWVILLHWYSTVLNPTSSNLKVIIFISNAWAVTNHFSIWLATSLSIFYLLKIVNFSRLIFHHLKRKAKSVVLVIVLGSLFFLVCHLVMKNTYINVWTEECEGNVTWKIKLRNAMHLSNLTVAMLANLIPFTLTLISFLLLIYSLCKHLKKMQLHGKGSQDPSTKIHIKALQTVTSFLILLAIYFLCLITSFWNSKMRPKEIVLMLCQAFGIIYPSFHSFILIWGNKTLKQTFLSVLWQVTCWAKGQNQSTP
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 20, Taste receptor type 2 member 49, T2R49.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: IF1_STRR6
Sequence: MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNYIRILAGDRVTVEMSPYDLTRGRITYRFK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYC6_THEVL
Sequence: MKKRFISVCAIAIALFVSLTPAALAADLANGAKVFSGNCAACHMGGGNVVMANKTLKKEALEQFGMYSEDAIIYQVQHGKNAMPAFAGRLTDEQIQDVAAYVLDQAAKGWAG
What is the function of this protein?
Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis.
What are the official names of this protein?
Cytochrome c6, Cytochrome c-553, Cytochrome c553, Soluble cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family. PetJ subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid lumen.
Protein: S5A3B_DANRE
Sequence: MSLFTHVLACLFGIGSWVAINGMWVELPLIVTAIPEGWLLPSYLTIIIQMANIGPLFITLMHRFRPGVLDERPVIYTIVAVGVVATFLLAFLWKHTLTFGDGEHSAALLSLSFLLSVVDCTSSVTFLPFMMRLQPQYLTTYFIGEGLSGLVPALVALVQGVGVVHCKNASANANFSLGNISQSLLETHYQPANFSTQGFFLFLSAMMMVCLGAFLLLNLHPAVAREHKSMKGYIDDSRRVEKIDLSQSPNDETPEQRPMLDFPEGSAIKQRSSFGKGTYSRTELVFIFVVLAWVNALTNAVLPSVQSYSCLPYGNQAYHLAATLSSVANPVACFIAMFVPIRSLVLMGVLTVTGTGFGAYIMAMAALSPCPLLINDDLGAALIVITWVIFVLSLSYVKVIIGVILRDEGHSALVWCGAVVQLGSMLGALSMFPLISVYRLFQSGDPCNTKCP
What is the function of this protein?
Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.
What are the official names of this protein?
Solute carrier family 52, riboflavin transporter, member 3-B, Riboflavin transporter 2-B, RFT2-B.
What is the protein family that this protein belongs to?
Belongs to the riboflavin transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SIPA_SALTS
Sequence: MVTSVRTQPPVIMPGMQTEIKTQATNLAANLSAVRESATATLSGEIKGPQLEDFPALIKQASLDALFKCGKDAEALKEVFTNSNNVAGKKAIMEFAGLFRSALNATSDSPEAKTLLMKVGAEYTAQIIKDGLKEKSAFGPWLPETKKAEAKLENLEKQLLDIIKNNTGGELSKLSTNLVMQEVMPYIASCIEHNFGCTLDPLTRSNLTHLVDKAAAKAVEALDMCHQKLTQEQGTSVGREARHLEMQTLIPLLLRNVFAQIPADKLPDPKIPEPAAGPVPDGGKKAEPTGINININIDSSNHSVDNSKHINNSRSHVDNSQRHIDNSNHDNSRKTIDNSRTFIDNSQRNGESHHSTNSSNVSHSHSRVDSTTHQTETAHSASTGAIDHGIAGKIDVTAHATAEAVTNASSESKDGKVVTSEKGTTGETTSFDEVDGVTSKSIIGKPVQATVHGVDDNKQQSQTAEIVNVKPLASQLAGVENVKTDTLQSDTTVITGNKAGTTDNDNSQTDKTGPFSGLKFKQNSFLSTVPSVTNMHSMHFDARETFLGVIRKALEPDTSTPFPVRRAFDGLRAEILPNDTIKSAALKAQCSDIDKHPELKAKMETLKEVITHHPQKEKLAEIALQFAREAGLTRLKGETDYVLSNVLDGLIGDGSWRAGPAYESYLNKPGVDRVITTVDGLHMQR
What is the function of this protein?
Actin-binding protein that interferes with host cell actin cytoskeleton.  It stimulates actin polymerization and counteracts F-actin destabilizing proteins.  Potentiates SipC activity; both are required for an efficient bacterial internalization.  In vitro, forms a complex with host cell protein T-plastin increasing actin bundling.  It inhibits ADF/cofilin-directed depolymerization both by preventing binding of ADF and cofilin and by displacing them from F-actin.  Also protects F-actin from gelsolin-directed severing and reanneals gelsolin-severed F-actin fragments.
What are the official names of this protein?
Cell invasion protein SipA, Effector protein SipA.
What is the protein family that this protein belongs to?
Belongs to the SipA/IpaA family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the type III secretion system 1 (SPI-1 TTSS).
Protein: SYH_SALG2
Sequence: MAKNIQAIRGMKDYLPGETAIWQRIEGTLKNVLGSYGYSEIRLPIVEQTPLFKRAIGEVTDVVEKEMYTFEDRNGDSLTLRPEGTAGCVRAGIEHGLLYNQEQRLWYIGPMFRHERPQKGRYRQFHQLGAEVFGLQGPDIDAELIMLTARWWRALGISEHVSLELNSIGSLEARANYRDALVAFLEQHQETLDEDCKRRMYTNPLRVLDSKNPDVQALLNDAPALGDYLDDDSREHFAGLCKLLDAAGIAYTVNQRLVRGLDYYNRTVFEWVTNSLGSQGTVCAGGRYDGLVEQLGGRATPAVGFAMGLERLVLLVQAVNPEFIASPVVDIYLVAAGAQTQSAAMTLAERLRDEMPGVKLMTNHGGGNFKKQFARADKWDARIALVLGESEVADGTVVVKDLRSGEQTAVAQDSVAAHLRTLLG
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LRAD2_HUMAN
Sequence: MEACCLLQLPQRLLLLGAAALTATALETADLAELCGQTWQGDGLLLRSHAASRRFYFVAPDTDCGLWVQAAAPGDRIRFQFRFFLVYSLTPAPPALNTSSPAPADPCAPGSYLQFYEGPPGAPRPLGSPLCGLNIPVPVASSGPFLGLRLVTRGRQPRVDFVGEVTSFRLGPCGAYFRCQNGRCIPSSLVCDPWGMDNCGDGSDQGSWSPADCRGPSPVPSQTGSTDAHTSRSLTPSPALGSAGSLWIAAERSSPAGRDPTRQDAALEGSTE
What are the official names of this protein?
Low-density lipoprotein receptor class A domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the LDLR family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: PURT_WOLSU
Sequence: MKFPSPFTPNSIKIMLLGSGELGKEVIIEAQRLGLETIAVDKYENAPAHGVAHRSYVVNMQDKEALLDLIQKENPTYILPEVEAISLEALLEAEEKGFCVIPSAKAVSLTMNRKGIRTFAAEEVGVKTSQYRFVKTLDELRSAAEEIGYPCVIKPVMSSSGHGQSVCRMAEEIEACFEEAKEARGDSSELIVEEFIPFDYEITLLTLNNGKKITFCDPIGHIQKGGDYIFSWQPAQMKKSVLKKAQKIARDVVSALGGRGIFGVELFIKKNEVYFSEVSPRPHDTGMVTLITQNFSEFALHLRAVLGAPLHVERISAGASAAFKSSQESQTPSVTLPKEAYAKDCDFRVFGKPVSHEGRRMAVLLIKDEEAESALKRAKKLIKKVSE
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: STING_NEMVE
Sequence: MRRAEENNGFGTIPKRRNQHTPFYASIGMIVVIIVAFTSYHITSYGDDRNRAMRQYSFTFSLAYLAFLVGELLRRCCLFAEEYRHIETRYNGSLKKAIQTTFSFGHNNVLFVASLLFFVVFVASNDPNGSSSVIQGNSTAEPHTEMRQTSGWQGLWGQFIISALLTPLVVHLLGLRELSKVEESQLNEKENKNVADGLAWSYYFGYLKFVLPELEKQIEKTSKFRSKEKFVKKMFILIPSNCFWDDKIPGSDYDPQNRITFEGNTEPLEKTRGGVFLRHYKHSVYEIKDGENEPWFCIMEYATPLLTLYDMSVAQPGELSREERDAQVVVFLRKLQDILEGDRACQGKYELVTFSPDRDLADVMLRKLKDSELEIGG
What is the function of this protein?
Sensor of cytosolic DNA from bacteria and viruses that promotes autophagy (PubMed:30842662).  Acts by recognizing and binding cyclic GMP-AMP (cGAMP), a messenger produced by CGAS in response to DNA in the cytosol (PubMed:26300263, PubMed:30842662).  Following cGAMP-binding, promotes the formation of autophagosomes, leading to target cytosolic DNA for degradation by the lysosome (PubMed:30842662).  Exhibits guanine base-specific ligand recognition.  Binds 3'-3'linked cGAMP, 2'-3' linked cGAMP and 3'-3' linked c-di-GMP with much greater affinity as compared to 3'-3' linked c-di-AMP (PubMed:26300263).  Lacks the C-terminal tail (CTT) found in mammalian orthologs which is essential for interferon signaling (PubMed:26300263).
What are the official names of this protein?
Stimulator of interferon genes protein, NvSTING, STING.
What is the protein family that this protein belongs to?
Belongs to the TMEM173 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: GUF1_CANDC
Sequence: MLLRPKSGNILKYGHFLSKRWLTASKLLYSVEEMKIKISQDQYRKALEERIDKIPIENYRNFSIVAHVDHGKSTLSDRLLEMTGVIKPGSKSQVLDKLDVERERGITVKAQTVSMFYNDGKQDYLLHLVDTPGHVDFRAEVSRSYASCGGALLLVDASQGVQAQTVANFYLAYSMGLKLIPIINKIDLDSANIAGAKEQIETTFELDPNDCIAVSAKTGLNVEQIIPSVIKNIPSPVCDVNKPLRALLVDSWHDPYVGVVMLVHIVDGKMKKGMKILSAHTNRTYDVKEVGIMYPDRTPTSFIKAGQVAYIIPGMKNPREALVGDTFYQMGKHEDLEPLPGFEEPKPMVFVGAFPADGKEFNAMDDQMQNLVLNDRSVTLEQETSNALGLGWRLGFLGSLHASVFKERLEKEYGAKIILTAPTVPYKIIYKNGEEKIVTNPDDFPDNQKHYDVESYMEPYVEAIMTVPNEYIGNVMTLCLNNRGEQKEIEYLTTGQVLLKYEIPTSQLVEDFFGKLKGCTKGYASLDYEEAGYRKSDIVKMQLCVNGEPQDALTTVIHRSQAQARGKEYVTRFKKYLSYQLFEVAIQAKINNKVVARETIKAKRKDVTQRLHAADISRYKKLLERQKEGKKQMKLSGKVTIKNDAYQAFLRRED
What is the function of this protein?
Promotes mitochondrial protein synthesis.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Binds to mitochondrial ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Translation factor GUF1, mitochondrial, Elongation factor 4 homolog, EF-4, GTPase GUF1, Ribosomal back-translocase.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: RECO_MYCTA
Sequence: MRLYRDRAVVLRQHKLGEADRIVTLLTRDHGLVRAVAKGVRRTRSKFGARLEPFAHIEVQLHPGRNLDIVTQVVSVDAFATDIVADYGRYTCGCAILETAERLAGEERAPAPALHRLTVGALRAVADGQRPRDLLLDAYLLRAMGIAGWAPALTECARCATPGPHRAFHIATGGSVCAHCRPAGSTTPPLGVVDLMSALYDGDWEAAEAAPQSARSHVSGLVAAHLQWHLERQLKTLPLVERFYQADRSVAERRAALIGQDIAGG
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: NCKP1_DANRE
Sequence: MSRGAMQPSQQKLAEKLTILNDRGIGMLTRIYNIKKACGDPKAKPSYLIDKNLESAVKFIVRKFPAVETRNNNQQLAQLQKEKSEILKNLALYYFTFVDVMEFKDHVCELLNTIDACQVFFDITVNFDLTKNYLDLVVTYTTLMLLLSRIEERKAIIGLYNYAHEMTHGSSDREYPRLGQMIVDYENPLKKMMEEFVPHGKSLSDALVSLQMVYPRRNLSADQWRNAQLLSLISAPSTMLNPAQSDTMPCEYLSLDTMEKWIVFGFILCHAALNSDPAALSLWKLALQSSTCLCLFRDEVFHIHKAAEDLFVNIRGYNKRVNDIRECKESALSHAGSMHRERRKFLRSALKELATVLADQPGLLGPKALFVFMALSFARDEIIWLLRHADNIQKKSTDDFIDKHIAELIFYMEELRAHVRKYGPVMQRYYVQYLSGFDAVVLNELVQNLSVCPEDESIIMSSFVNTMTSLSVKQVEDGEVFDFRGMRLDWFRLQAYTSVSKASLGLADHRELGKMMNTIIFHTKMVDSLVEMLVETSDLSIFCFYSRAFEKMFQQCLELPSQSRYSISFPLLCTHFMSCTHELCPEERHHIGDRSLSLCNMFLDEMAKQARNLITDICTEQCTLSDQLLPKHCAKTISQAVNKKSKKQTGKKGEPEREKPGVESMRKNRLLVTNLDKLHTALSELCFSINYVPNMMVWEHTFTPREYLTSHLEIRFTKSIVGMTMYNQTTQEIAKPSELLTSVRAYMTVLQSIENYVQIDITRVFNNVLLQQTQHLDSHGEPTITSLYTNWYLETLLRQVSNGHIAYFPAMKAFVNLPTENELTFNAEEYSDISEMRSLSELLGPYGMKFLSESLMWHISSQVAELKKLVVDNVEVLTQMRTSFDKPDHMAALFKRLTSVDSVLKRMTIIGVILSFRSLAQEALRDVLSCHIPFLVSSVEDFKDHIPRETDMKVAMNVYELSSAAGLPCEIDPALVVALSSQKSENISPEEEYKIACLLMVFVAVSMPTLASNVMSQYSPAIEGHCNNIHCLAKAINQIAAALFTIHKGSIEDRLKEFLALASSSLLKIGQETDKTTTRNRESVYLLLDMIVQESPFLTMDLLESCFPYVLLRNAYHAVYKQSVSSSA
What is the function of this protein?
Part of the WAVE complex that regulates lamellipodia formation.  The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.  Actin remodeling activity is regulated by RAC1 (By similarity).  Plays a role in neural tube closure.
What are the official names of this protein?
Nck-associated protein 1, NAP 1.
What is the protein family that this protein belongs to?
Belongs to the HEM-1/HEM-2 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein; Cytoplasmic side. Cell projection, lamellipodium membrane; Single-pass membrane protein; Cytoplasmic side. Note=At the interface between the lamellipodial actin meshwork and the membrane.
Protein: PRMA_CAMJR
Sequence: MQKKYYELFFIVEERYKNLFLDFAFDLGIEAIEEKDNGVYIRSHESLEEFSWALEIFAQKLTTTFNLNHKIISNLSLVEKENKDWIQEYKKGIKPILVDNVYIHTTWQEEKKNCINIKINPALAFGSGHHESTYSCVKFLQKFSKSKLRALDLGCGSGILGIIMAKFGCNVEICDTDELAIDSSLENARLNGVDFHKAWCGSIDKANGLYNLIVANIIADVILILEKDIKNHLEDNAILILSGILDKYSTRIKEKFQDLELIDEIQINEWCSFVYKNNKKG
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA_PARXL
Sequence: MDKLVIEGGYPLSGEVVVSGAKNAALPILCAGLLSAQPVHLENVPDLQDVRTMLKLLGQMGVQIESGDGRVSLNASKVDNLVAPYEMVKTMRASILVLGPLVARFGHARVSLPGGCAIGARPVDQHIKGLQAMGAEITIEHGFIEARAKRLKGTRIVTDMITVTGTENLLMAAVLAEGETVIENAAREPEVGDLAHLLVEMGAKIEGIGTDRLVIQGVDKLHGAKHTVIPDRIEAGTFLCAVAAAGGDVTLRKVRPLILEAVTEKLREAGVTVEEGDDWMRVRMNKRPNAVTFRTSEYPAFPTDMQAQFMALNTIATGTSQVVETIFENRFMHVQELNRLGANITIDGNTALVTGVEQLSGAKVMATDLRASASLVIAALRADGETLIDRIYHLDRGYDRMETKLTALGAKVRRVSGSQA
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBIM2_METPE
Sequence: MHIMEGFLPAGWCLVWWLIALPFLVMGIIQLRRMMKEDREYLPLLGVCGAFIFILSALKLPSVTGSCSHPTGTGLSTICFGYCVTAVVGAIVLLFQALLLAHGGLSTMGANMVSMAIGGPIAGYAVYKLMKDTSINIYVTVFLASAVADIVTYIITSFELALAYPAQVGGFLASFSAFFSIFAITQIPLSIMEGVVLALVFKYIIQLKPEIILKLHVFSEEQIAKARLAGDAEVA
What is the function of this protein?
Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
What are the official names of this protein?
Putative cobalt transport protein CbiM 2, Energy-coupling factor transporter probable substrate-capture protein CbiM 2, ECF transporter S component CbiM 2.
What is the protein family that this protein belongs to?
Belongs to the CbiM family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.