PharMolix/UniProtQA huggingface dataset:
Protein: ZNF2_MOUSE
Sequence: MAAVSPPTRCQALVTFEDVAVTFTDDEWKRLVPVQRALYKAVMLENYESIISLGLPVPRPDVILQFKRRGEPWIRGFHGSEEKTWPESVSLDLETKPETLDASRGTLREIHRKQSSLCPKREIQTLTGGPEPEKESPKARTCKKPLSLDKGLHQMSAPSKKALTKHQDQECSECGKTFFDHSSLIRHQRTHTGEKPYDCPECGKAFSHRSSLSRHLMFHTGESPYECDACGKAFFDRSSLTVHQRIHTGEKPFKCNDCGKAFFDRSSLTRHQRIHTGESPYECQQCGKAFSQKSILTRHLLTHTGRKPYECRDCGKAFYGVTSLNRHQKVHTEEPRYQCSECGKAFFDRSSLTQHQKIHTGDKPYECGECGKAFSQRCRLTRHQRVHTGEKPFECSVCGKEFSSKSSIIQHQRRYAKQGIDRGGSMS
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 2, Zinc finger protein 661, Zfp-661.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARLY_CORGB
Sequence: MEQHGTNEGALWGGRFSGGPSEAMFALSVSTHFDWVLAPYDVLASKAHAKVLHQAELLSDEDLATMLAGLDQLGKDVADGAFGPLPSDEDVHGAMERGLIDRVGPEVGGRLRAGRSRNDQVATLFRMWVRDAVRDIALGTTELVDALSAQAKAHADAIMPGKTHFQAAQPVLLAHQLLAHAQPLLRDIDRIRDLDKRLAVSPYGSGALAGSSLKLNPEAIAEELGFDSAADNSIDATSSRDFASETAFVLAQLAVDMSRLAEEIIAWCTPEFGYITLSDSWSTGSSIMPQKKNPDVAELTRGKSGRLIGNLTGLLATLKAQPLAYNRDLQEDKEPIVDSVAQLNLLLPAMTGLVSTLTFNTERMRELAPAGFTLATDLAEWMVRQGVPFREAHEASGACVRIAESRGVDLIDLTDEELSGVDARLTPEVREVLTIDGAVASRATRGGTAGVRVAEQRARVDAASTAHAEWARAGVRR
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_SULDN
Sequence: MAKKIMGYIKLQIEAGKATPAPPVGPALGQRGVNIMEFTKAFNEKTKDKMGFKVPVVITVFTDKSFTFVVKQPPASALLMHAAGLKGGSSNPLKNKVAKLTQAQLMEIVNRKIEDLNTDDKEAAAKTIAGSARSIGIEIVD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: POTA_STRSV
Sequence: MKKPIIEFKNVSKVFEDNNTVVLKDINFELEEGKFYTLLGSSGSGKSTILNIIAGLLDATDGDIFLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAFPLRLRKVDKKEIQERVTEVLKMVQLEGFERRSIRKLSGGQRQRVAIARAIINQPRVVLLDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQSGTPVDIYDEPINHFVATFIGESNILPGKMIEDYLVEFNGKRFEAVDGGMRPNESVEVVIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIGLHFEPEDIHIMRLNETEEEFDARIEEYVEVEEQEAGLINAIEEERDEENNL
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: EMTA_ECOBW
Sequence: MKLRWFAFLIVLLAGCSSKHDYTNPPWNAKVPVQRAMQWMPISQKAGAAWGVDPQLITAIIAIESGGNPNAVSKSNAIGLMQLKASTSGRDVYRRMGWSGEPTTSELKNPERNISMGAAYLNILETGPLAGIEDPKVLQYALVVSYANGAGALLRTFSSDRKKAISKINDLDADEFLEHVARNHPAPQAPRYIYKLEQALDAM
What is the function of this protein?
Murein-degrading enzyme.  May play a role in recycling of muropeptides during cell elongation and/or cell division.  Preferentially cleaves at a distance of more than two disaccharide units from the ends of the glycan chain.
What are the official names of this protein?
Endo-type membrane-bound lytic murein transglycosylase A, Peptidoglycan lytic endotransglycosylase.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: THII_THEPX
Sequence: MQDILLIKYGELALKGDNRSFFENKLIKNIKHALSDFKEVKVEKTHGRIYVECDGDIEEVIERLKKVFGIVGITKAKKTDLNLDEIFKAAVELMKGHEGKTFKVETKRPNKSFPYNSMEVSRRVGAAVLKNVKNLKVDVHNPDVLLNVEIREMAFVYAGVIEGIGGLPLGTNGKATVLLSGGIDSPVAAWMMMKRGVEVEAVYFHSPPYTSERAKDKVVDLCKVLSQYGQRIKLHVVHFTDLQLEIYEKCPPKFTTIIMRRMMMKIAEKIAQKNGSMALITGESLGQVASQTIESLYVTNASVSMPIFRPLIGMDKTEIIDLAQKISTFEISIRPYEDCCTIFVPKHPATKPKLEKVIEAEQKMEYQKYIDNFEEEVIEV
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK33_ARATH
Sequence: MAKGKDVRVTIILECTSCVRNDIKKEAAGISRYITQKNRHNTPSRLELRKFCPYCYKHTIHGEIKK
What are the official names of this protein?
50S ribosomal protein L33, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RISB_CUTAK
Sequence: MSSRTTLGLSAPDLSGLDGSGLKVAVVAAQWHGTVMTGLLDGALRGLVDSGVHDPAVIRVPGSFELPVACASLADHFDALVALGVIIRGGTPHFDYVCDAATRGITDVAVRTKTPIGFGILTCDDEAQALDRAGLEGSHEDKGYEAAQAAIATLTALSTALASGPS
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: RIPA_LUFAE
Sequence: MKRFTVLILAIFVAASTVEADVRFSLSGSSSTSYSKFIGDLRKALPSNGTVYNITLLLSSASGASRYTLMTLSNYDGKAITVAVDVTNVYIMGYLVNSTSYFFNESDAKLASQYVFKGSTIVTLPYSGNYEKLQTAAGKIREKIPLGFPALDSAITTLFHYDSTAAAAAFLVIIQTTAEASRFKYIEGQIIERISKNQVPSLATISLENEWSALSKQIQLAQTNNGTFKTPVVITDDKGQRVEITNVTSKVVTKNIQLLLNYKQNVAAFDEDVSAKH
What are the official names of this protein?
Ribosome-inactivating protein luffin-alpha, rRNA N-glycosidase.
What is the protein family that this protein belongs to?
Belongs to the ribosome-inactivating protein family. Type 1 RIP subfamily.
Protein: PROA_CUPMC
Sequence: MTEFDLHAYMTRVGQQARAASRAMARASTADKNRALLTIAAAIRRDADKLKAVNARDVERARTNGQDAAFIDRLTLSDKAIATMAAGLEQIAALADPIGEISNMKFRPTGIQVGQMRVPLGVIGIIYESRPNVTIDAAALCLKSGNSTILRGGSEAIESNTALAALVAEGLAAAGLPSEAVQVIETTDRAAVGRLITMTEYVDVIVPRGGKSLIARLMEEARVPMIKHLDGICHVYIDDDADLEKAVRVCDNAKTQRYAPCNTMETLLVSREIAAKALPPLCRIYQEKGVELRVCPATRATLEAAGFSGLVDATEEDWRLEYLAPVLAIRTVDGLDAAIAHINTYGSAHTDSIITENYTTGMRFLREVDSASVMINASTRFADGFEYGLGAEIGISNDKLHARGPVGLEGLTSLKYVVFGHGEIRT
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CMOB_STUS1
Sequence: MNLDLTPLAWRLAGTPLAAWANDVQQQLDAKLAIGHGDLPRWRRAVDALPTLMPTQIELRECFRLAAPCDEATRQATREALMGLSPWRKGPFEVFGVHVDTEWRSDWKWARVAPHLDLAGKRILDVGCGNGYYMWRMLGAGADSVVGVDPNWLFFCQFHAMKRYLPELPAWHLPFALEELPPKLEGFETVFSMGVLYHRRSPVDHLLDLKDCLVRGGELVLETLVVEGDENTALVPEDRYAQMRNVWFLPSVPALERWLRRAGFVDVRCVDVSVTSVEEQRSTYWMRYQSLPDFLDPQDHGRTVEGLPAPMRAVLLARKP
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: QUEC_METC4
Sequence: MPEDAAVAGGEAGALVLFSGGQDSATCLAWALDRFPHVETLGFDYGQRHWVELDRRAALRQGLTALDPAWGRRLGPDHTLALAALGEISDTALTRDSAIAFARDGLPNTFVPGRNLAFLTFAAALAYRRGLRHIVGGMCETDYSGYPDCRDDTIKALQVALNLGMERRFVLHTPLMWIDKAQTWALAETLGGRALVELVVEESHTCYLGERGARHEWGYGCGTCPACDLRAKGFSRYLAARAD
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: MFD4A_XENTR
Sequence: MWLDERLLALFRRNFQSTLTYWSVFFSFGLCIAFLGPTLLDLRCQTHSSLQDITWVFFAQQFCLLVGSTLGGVFKRTVKQSLFLLFLSSLTISVVFVIIPFCDHVGVLALVMAIAGLAMGCIDTISNMQLVKIYQQDSAIFLQVLHFFVGFGALLSPLIADPFLSDTNCIQSNATQNGSRNLEHIRNSLVPHHPRNVSHYVLPLQGALVTQVSYAFWIMAAINLPVPVAVFYLIYKKGMVPGCHIQNGGLLSADELAMEMHKENDSQKIEAHEEHGHAVSLLCCQNKKIWNAPFTFFAIHMCAAVTLFMTDGIVGEYSGFVYSYAVEQPLNLAHKTAGYLPSLFWAFITLGRLISIPVSYKMAPRSMLFINLIGVTATFLFLLLSQNSTTGMFVGTALLGLWLSSVFPSMLAYTEDILNYKGCATTVLVTGAGMGEMVLQILVGSVMQTQGSYSFLVCGICLSSLAFTLYAVLLVVDSLHNRASEDSACKPPGLDGEATSYQS
What are the official names of this protein?
Major facilitator superfamily domain-containing protein 4A, Major facilitator superfamily domain-containing protein 4.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: XERC_ROSCS
Sequence: MNEQVEAFLRHLADERNLSANTIAAYRTDLEQFCEFLHGRRLFAWHDVTHDDVLAFLIDLRERRYASSTVARRVAAVKSFFTFLTGRGIVQRDPTERIDSPKVDRDLPRALTPRQVDELLELPLRSPTPERIRDKAMLELLYATGVRVSELVALNVNDVDLERNEVRCIGKNGRVRVLPINGSAATALEEYFDISRNQLARGSGSSTEALFLNHRGKRLTRQGFWLILKQYAEELGLSDLTPHVLRHSFAVHMLNAGFDLRAVQELLGHTSISTTQIYTHLNHESSHTPHAHPAPRASEVNGVRDEQALVPEEK
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BCHL_METS4
Sequence: MNIAIRNPVATRPAERREEGSLQVALDPDLRIDTAKVFAVYGKGGIGKSTTSSNLSVAFSKLGKRVLQIGCDPKHDSTFTLTKRLAPTVIDALEAVKFHAEELRVEDFVVEGYNGVMCVEAGGPPAGTGCGGYVVGQTVKLLKEHHLLEETDVVVFDVLGDVVCGGFASPLQHADRALIVTANDFDSIFAMNRIVAAIHAKAKNYGVRLGGVIANRSAATDEIDRFNAAVGLRRLAHFQDLDVVRRSRLRKATLFEMESSPELDAVLAEYLALAEALWAGVEPLEAEPMRDRDLFEFLGFD
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
What are the official names of this protein?
Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein, DPOR subunit L, LI-POR subunit L.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: ARYC_NOCGL
Sequence: MDVAEYAAHDATGLAELIREGQVSACEV
What are the official names of this protein?
Aryl acylamidase.
Protein: EBAG_STRPL
Sequence: MFTPVRRRVRTAALALSAAAALVLGSTAASGASATPSPAPAPAPAPVKQGPTSVAYVEVNNNSMLNVGKYTLADGGGNAFDVAVIFAANINYDTGTKTAYLHFNENVQRVLDNAVTQIRPLQQQGIKVLLSVLGNHQGAGFANFPSQQAASAFAKQLSDAVAKYGLDGVDFDDEYAEYGNNGTAQPNDSSFVHLVTALRANMPDKIISLYNIGPAASRLSYGGVDVSDKFDYAWNPYYGTWQVPGIALPKAQLSPAAVEIGRTSRSTVADLARRTVDEGYGVYLTYNLDGGDRTADVSAFTRELYGSEAVRTP
What is the function of this protein?
Cleaves asparagine-linked oligomannose and hybrid, but not complex, oligosaccharides from glycoproteins.
What are the official names of this protein?
Endo-beta-N-acetylglucosaminidase H, DI-N-acetylchitobiosyl beta-N-acetylglucosaminidase H, Endoglycosidase H, Endo H, Mannosyl-glycoprotein endo-beta-N-acetyl-glucosaminidase H.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family.
Protein: EFTS_PSET1
Sequence: MAVTTALVKELRERTGAGMMDCKKALTETDGDIELAIENMRKSGAAKAAKKAGNIAAEGAIIIKKNGNVAVLVEVNCQTDFVAKDVSFLAFADKVAEAAIADTVTIEDLQAKFEEARVELVTKIGENINVRRLQYITGENLVEYRHGDRIGVVVAGVADEETLKHVAMHVAASSPEYLTPSDVPADVVAKEQQVQIEIAMNEGKSAEIAEKMVVGRMKKFTGEVSLTGQAFIMEPKKTVGEILKEKNATVTSFVRVEVGEGIERKEEDFAAEVAAQIAAAKAK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRCB1_HALSA
Sequence: MTGAVAPPAVLVAAGGALGAVLRWRVVAATPTTEYPAGTLVVNVVGSFVLAALTFAAADADTMLLFGTGACGAFTTFASFSVDVVALVDADRPVAAAGHALGNLLGAGLAVALAWLLVA
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 1.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: APT_STRCO
Sequence: MTEPTGITELLLSRIRDVADYPEPGVVFKDITPLLADPGAFAALTDALAEAAGRTGATKVVGLEARGFILGAPVALRAGLGFIPVRKAGKLPGATLSQAYDLEYGSAEIEVHAEDLTAGDRVLVVDDVLATGGTAEASLELIRRAGAEVAGLAVLMELGFLGGRARLEPALAGAPLEALLTV
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NOLW_SINFN
Sequence: MPTTPIPFTPLHMFRRLLCVGLFLFAGIHTTLGATLPLPSTSYKYTVLDQDLSAALQEFGNNLKISVNISAEVKGRIRGRIPELSPREFLDRLTDLYDLQWYYDGVVLYVSAAKEAQTRMLVLSSVHFSAFKLALDKLDISDERYPVRPAPGNGLVLVSGPPRFMALIEQTLNGLLAVAQAQPRATDTPARESVMVLFRGSSTTVVRGGRPEVFYTSEMLPENDDGGKAELSKK
What are the official names of this protein?
Nodulation protein NolW.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: HASC_STRPY
Sequence: MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEEALKSGIEEILVVTGKAKRSIEDHFDSNFELEYNLQAKGKNELLKLVDETTAINLHFIRQSHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITNASAKPLTKQLMEDYDKTHASTIAVMKVPHEDVSSYGVIAPQGKAVKGLYSVDTFVEKPQPEDAPSDLAIIGRYLLTPEIFDILERQTPGAGNEVQLTDAIDTLNKTQRVFAREFKGNRYDVGDKFGFMKTSIDYALEHPQVKEDLKNYIIKLGKALEKSKVPTHSK
What are the official names of this protein?
UTP--glucose-1-phosphate uridylyltransferase, Alpha-D-glucosyl-1-phosphate uridylyltransferase, UDP-glucose pyrophosphorylase, UDPGP, Uridine diphosphoglucose pyrophosphorylase.
What is the protein family that this protein belongs to?
Belongs to the UDPGP type 2 family.
Protein: RUTC_ECOL6
Sequence: MPKSVIIPAGSSAPLAPFVPGTLADGVVYVSGTLAFDQHNNVLFADDPKAQTRHVLETIRKVIETAGGTMADVTFNSIFITDWKNYAAINEIYAEFFPGDKPARFCIQCGLVKPDALVEIATIAHIAK
What is the function of this protein?
Involved in pyrimidine catabolism.  Catalyzes the deamination of 3-aminoacrylate to malonic semialdehyde, a reaction that can also occur spontaneously.  RutC may facilitate the reaction and modulate the metabolic fitness, rather than catalyzing essential functions.
What are the official names of this protein?
3-aminoacrylate deaminase RutC, 3-AA deaminase.
What is the protein family that this protein belongs to?
Belongs to the RutC family.
Protein: DEF_PROMS
Sequence: MANHFSQLAKKSRTNGNAEKIAKEQSGKPFLDIYKLGDDVLRQNSKRITKVDESIRKLAREMLQSMYAAKGIGLAAPQIGINKELLVIDVNFEDSAAEPLILINPEITDFGTTLNSYEEGCLSIPGVYLNVVRPSTIKLKFRDEMGRPRKMKADGLLARCIQHEMDHLNGILFVDRVTSKDDLNKELLKEGFNEKDVISIN
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: SPG21_HUMAN
Sequence: MGEIKVSPDYNWFRGTVPLKKIIVDDDDSKIWSLYDAGPRSIRCPLIFLPPVSGTADVFFRQILALTGWGYRVIALQYPVYWDHLEFCDGFRKLLDHLQLDKVHLFGASLGGFLAQKFAEYTHKSPRVHSLILCNSFSDTSIFNQTWTANSFWLMPAFMLKKIVLGNFSSGPVDPMMADAIDFMVDRLESLGQSELASRLTLNCQNSYVEPHKIRDIPVTIMDVFDQSALSTEAKEEMYKLYPNARRAHLKTGGNFPYLCRSAEVNLYVQIHLLQFHGTKYAAIDPSMVSAEELEVQKGSLGISQEEQ
What is the function of this protein?
May play a role as a negative regulatory factor in CD4-dependent T-cell activation.
What are the official names of this protein?
Maspardin, Acid cluster protein 33, Spastic paraplegia 21 autosomal recessive Mast syndrome protein, Spastic paraplegia 21 protein.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Note=Partially localized in the cytosol but also accumulated on an intracellular vesicular compartment. Colocalizes with CD4 on endosomal/trans-Golgi network.
Protein: BETA_STAAS
Sequence: MSNKNKSYDYVIIGGGSAGSVLGNRLSEDKDKEVLVLEAGRSDYFWDLFIQMPAALMFPSGNKFYDWIYSTDEEPHMGGRKVAHARGKVLGGSSSINGMIYQRGNPMDYEGWAEPEGMETWDFAHCLPYFKKLEKTYGAAPYDKFRGHDGPIKLKRGPATNPLFQSFFDAGVEAGYHKTPDVNGFRQEGFGPFDSQVHRGRRMSASRAYLHPAMKRKNLTVETRAFVTEIHYEGRRATGVTYKKNGKLHTIDAKEVILSGGAFNTPQLLQLSGIGDSEFLKSKGIEPRVHLPGVGENFEDHLEVYIQHKCKEPVSLQPSLDIKRMPFIGLQWIFTRTGAAASNHFEGGGFVRSNNEVDYPNLMFHFLPIAVRYDGQKAAVAHGYQVHVGPMYSNSRGSLKIKSKDPFEKPSIRFNYLSTEEDKKEWVEAIRVARNILSQKAMDPFNGGEISPGPEVQTDEEILDWVRRDGETALHPSCSAKMGPASDPMAVVDPLTMKVHGMENLRVVDASAMPRTTNGNIHAPVLMLAEKAADIIRGRKPLEPQYIDYYKHGVHDENEGAIEVKPYAK
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
What are the official names of this protein?
Oxygen-dependent choline dehydrogenase, CDH, CHD, Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: US6NL_HUMAN
Sequence: MNSDQDVALKLAQERAEIVAKYDRGREGAEIEPWEDADYLVYKVTDRFGFLHEEELPDHNVAVERQKHLEIERTTKWLKMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKLKHRARGCSPDIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYSIYNTEVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEHHEKILNKFLSKLKQHLDSQEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLTAMSYTILKLHKKHLMKLSMEELVEFFQETLAKDFFFEDDFVIEQLQISMTELKRAKLDLPEPGKEDEYPKKPLGQLPPELQSWGVHHLSNGQRSVGRPSPLASGRRESGAPHRRHEHSPHPQSRTGTPERAQPPRRKSVEEESKKLKDEADFQRKLPSGPQDSSRQYNHAAANQNSNATSNIRKEFVPKWNKPSDVSATERTAKYTMEGKGRAAHPALAVTVPGPAEVRVSNVRPKMKALDAEDGKRGSTASQYDNVPGPELDSGASVEEALERAYSQSPRHALYPPSPRKHAEPSSSPSKVSNKFTFKVQPPSHARYPSQLDGEARGLAHPPSYSNPPVYHGNSPKHFPTANSSFASPQFSPGTQLNPSRRPHGSTLSVSASPEKSYSRPSPLVLPSSRIEVLPVDTGAGGYSGNSGSPKNGKLIIPPVDYLPDNRTWSEVSYTYRPETQGQSWTRDASRGNLPKYSAFQLAPFQDHGLPAVSVDSPVRYKASPAAEDASPSGYPYSGPPPPAYHYRNRDGLSIQESVLL
What is the function of this protein?
Acts as a GTPase-activating protein for RAB5A and RAB43.  Involved in receptor trafficking.  In complex with EPS8 inhibits internalization of EGFR.  Involved in retrograde transport from the endocytic pathway to the Golgi apparatus.  Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network.  Required for structural integrity of the Golgi complex.
What are the official names of this protein?
USP6 N-terminal-like protein, Related to the N-terminus of tre, RN-tre.
What are the subcellular locations of this protein?
Golgi apparatus. Cytoplasmic vesicle.
Protein: RL19_LEPIN
Sequence: MNQLLREVLTPDAERTQNFTVGDTVKVHYKIVESGKERVQIYEGVVISVANEANGKTFTVRRVSYDVGVERIFPLFSPRIAKIELIRKGKVRRAKLYYLRNLAGKAARIKELKGGKALVSEDRKRQQAAAATKSTTTE
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: TX17_PHORI
Sequence: AFCRFNGQQCTSDGQCCNGRCINAFQGRICIG
What are the official names of this protein?
U6-ctenitoxin-Pr1a, U6-CNTX-Pr1a, Venom protein PRTx17C1.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 17 (21C2) family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1077_KLEP7
Sequence: MIIYLHGFDSNSPGNHEKVMQLQFIDPDVRLISYSTRHPKHDMQHLLKEVDKMLQLTADDRPLICGVGLGGYWAERIGFLCDIRQAVFNPNLFPHENMEGKIDRPEEYADIATKCVTNFREKNRDRCLVVLSRQDEALDSQRSADLLHHYYEIIWDEEQTHKFKNISPHLQRLKAFKTLG
What are the official names of this protein?
UPF0227 protein KPN78578_10770.
What is the protein family that this protein belongs to?
Belongs to the UPF0227 family.
Protein: KDM4C_MOUSE
Sequence: MEVVEVESPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQCYDDIDNLLIPAPIQQMVTGQSGLFTQYNIQKKAMTVKEFRQLANSSKYCTPRYLDYEDLERKYWKNLTFVAPIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRHKMTLISPSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYGKVAKLCTCRNDMVKISMDIFVKKFQPDRYQIWKQGKDIYTIDHTKPTPESTPEVKTWLQRKKKLRKPPKSLQGNKPLCKRPKPEEDEEFAEFSGEEGANPAMGPRHLKVTEKPEKALKLGKLEESSAKEALDTRIQVDQSLLNDTKLSGKGCISSSVTAEIPPEDNRASAVISPSQLKEGADCIPLSHGHQAGKESHLLKILKLESPKIPSPLPESNKVLTEGEENDEEGHGSNLEPGEIPEALSEERNGLNIPKIIEGQPKTTKSWRHPLGKPPARSPMTLVKQQVASDEELPEVLSIDEEVEETESWAKPLIHLWQTKSPNFMAEQEYNATVAKMEPNCAICTLLMPYYKPDSSKEENDSRWETAVNEVVQSGRKTKPIIPEMCFIYSEENVDYSPPNAFLEEDGTSLLISCAKCFVRVHASCYGVPSHEVCDGWLCARCKRNAWTAECCLCNLRGGALKQTKNNQWAHVICAVAVPEVRFTNVPERTQIDVDRIPLQRLKLKCIFCRHRVKKVSGACIQCSYGRCPASFHVTCAHAAGVLMEPDDWPYVVNITCFRHRVNSNAKSKTCEKAISVGQTVITKHRNTRYYSCRVIDVTSQTFYEVMFDDGSFSRDTFPEDIVSRNCVKLGPPAEGEVIQVKWPDGKLYGAKYLGSNVAYMYQVEFEDGSQIAMKREDIYTLDEELPKRVKARFSTASDMRFEDTFYGADVIQGERKRQRVLSSRLKNEYVDDPVYRTFLKSSFQKKCQKRQ
What is the function of this protein?
Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code.  Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'.  Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues.  Demethylation of Lys residue generates formaldehyde and succinate.
What are the official names of this protein?
Lysine-specific demethylase 4C, JmjC domain-containing histone demethylation protein 3C, Jumonji domain-containing protein 2C, [histone H3]-trimethyl-L-lysine(9) demethylase 4C.
What is the protein family that this protein belongs to?
Belongs to the JHDM3 histone demethylase family.
What are the subcellular locations of this protein?
Nucleus.