PharMolix/UniProtQA huggingface dataset:
Protein: TRUA_NITHX
Sequence: MPRYKLTIEYDGGPFCGWQYQDNGPSVQGALEAAVKAICGDAVRVHGAGRTDAGVHALAQVAHCDIAKHFAPNRLRDGLNAHLRPHPIGVLTAEIVPDTFEARFSALRRHYVYRIANRRANLAIDVGHVWRVPRPLDTLAMHAAAQRLIGKHDFTTFRDTECQAKSPEKTLDQLDVVRNGDTVTIVTSARSFLHSQVRSMVGSLVWVGHGRWSADDLSNALAERRREACGPVAPPDGLYLVRVDY
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: TUSC_PASMU
Sequence: MKLAFVFRSTPFGRASTREGLDALLAATAFCDEQDIAVFFLDDGVFSLLNHQDPAQILQKDVVNMFKLLDLYDIEQRYICLESLATAKMTASDCIITCEKMARAALLTLLGKAERVLTF
What is the function of this protein?
Could be part of a sulfur-relay system.
What are the official names of this protein?
Protein TusC homolog.
What is the protein family that this protein belongs to?
Belongs to the DsrF/TusC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAS26_CAEEL
Sequence: MTSSLVLILAPLALVAIGEAAFGNSSKIFEIPGLEVMASDKYPHFTTIETVSRTKVHRHRREVIAGQIYDWNSYEIPFQIWGGDYNFQSLIRRGIRMWEDSTCLRFKENQQSRDAIRYVLEKGDSCFTEYIGRNGGHQDIIIGSECAEEYVVAHETGHALGFWHTHQRPDRDRHISINWKNVMEEATASFMPFRSMLQAFGIRQVSPRRVPYDYGSLMHYHAVAHAVKVSDFTIVPKELKYVTTMGTEKMAFLDAKVINDIYCPNACQGRNHLNCLAGGYPDPNNCNVCRCPEGLGGPDCGRLQPSPCGGEIHASDQWQTLSSPSGRDVHCYWRISVPEGSRVRFRLSDGEFPCSYGCQSYVEIKHKLDVRLTGFRSCCYRPKEDTVSESNQIFVIYHPNGRTARFSLRFRRQA
What is the function of this protein?
Metalloprotease.
What are the official names of this protein?
Zinc metalloproteinase nas-26, Nematode astacin 26, Tollish protein 1.
What are the subcellular locations of this protein?
Secreted.
Protein: ECM1_RAT
Sequence: MGTIRSSALILACLALASAASEGAFKVSDQREMKPEHLFQHLHEVGYAAPPSPPQTRRLQVHHSETSPHDPPLFEEQKEVQPPSSPEDIPVYEEEWLTFLNPNVGKVDPALPQEAIPLQKEQPPPRIPIEQKEIDPPVQHQEEIVQSRQKEEKPPTLTGQHPPEPRTWNPARHCQQGRRGIWGHRLDGFPPGRPSPDNLKQICLPERQHVVYGPWNLPQTGYSHLSRQGEALNLLETGYSRCCRCRSDTNRLDCVKLVWEDAMTQFCEAEFSVKTRPHLCCKQRGEERFSCFQKEAPRPDYLLRPCPIHQTGISSGTQLPFPPGLPTPDNVKNICLLRRFRSVPRNLPATDAIQRQLQALTRLETEFQRCCRQGHNHTCTWKAWEDTLDGYCDRELAIKTHPHSCCHYPPSPARDECFAHLAPYPNYDRDLLTVDLSRVTPNLMDHLCGNGRVLSKHKQIPGLIQNMTVRCCELPYPEQACCGEEEKLAFIEDLCGPRRNSWKDPALCCTLSPGDKQANCFNTNYLRNVALVAGDTGNATGLGQQGPTGGTNVGPAPGSKEE
What is the function of this protein?
Involved in endochondral bone formation as negative regulator of bone mineralization.  Stimulates the proliferation of endothelial cells and promotes angiogenesis.  Inhibits MMP9 proteolytic activity (By similarity).
What are the official names of this protein?
Extracellular matrix protein 1, Secretory component p85.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: Y160_RICM5
Sequence: MSEVVVKEQLEQYISKIERLEQEKADLSQEVKDIFQDASSHGFDVKAMKSILKLKKLDKDKLAEQDAMLELYRDTLGI
What are the official names of this protein?
UPF0335 protein RMA_0160.
What is the protein family that this protein belongs to?
Belongs to the UPF0335 family.
Protein: RECR_FINM2
Sequence: MSLYPKAMDELIKNLSNLPTIGRKSARRLAYRIIDMDPKKVDELVESIVNVKTNIRPCANCGNLTDKKLCDICSDQKRDNSVITVVEDSMNVISIEKTGEYNGKYHVLGGLLSPRDNIAPQDLNLENLFLRCKKDYVKEVILALSPTTNGDLTTNFIIEVLKNEEYNVKVSRIAMGVPLGANLEYYDEMSLYKAILDRREIK
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: APT_MYCS2
Sequence: MTQHHDTAEVSRVIATLTREVADFPEPGIQFKDLTPLLADARGLRVVTDALADIASGADLVAGLDARGFLLGAAVATRLGTGVLAVRKGGKLPPPVHGATYQLEYGTATLEIPAEGIDIAGRNVVIIDDVLATGGTLAAAARLLGDCGANVTGAGVVLELEALRGREAVAPLGVRSLHII
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOZ_THET8
Sequence: MAEPGIDKLFGMVDSKYRLTVVVAKRAQQLLRHGFKNTVLEPEERPKMQTLEGLFDDPNAVTWAMKELLTGRLVFGENLVPEDRLQKEMERLYPVEREE
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: RS9_MYCLB
Sequence: MTETSEAVEIAVGTPAAKHSESFVFERSIQTVGRRKEAVVRVRLVLGTGKFDLNGRSLEDYFPNKVHQQLIKAPLVTVERTRNFDIFALLHGGGPSGQAGALRLGIARALILASPEDRPALKKAGFLTRDPRSTERKKYGLKKARKAPQYSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: TY31_PHAJA
Sequence: QDKPFWSPPIYPV
What are the official names of this protein?
Tryptophyllin-T3-1, Pj-T3-1.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Tryptophillin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PETG_ZYGCR
Sequence: MVEPLLSGIVLGLIPITLAGLFVTAYLQYRRGDQLDL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: NTPPB_SYNC1
Sequence: MKIIVLASTSPYRMQLMRQLGLPFHVAAPQYQEQIDQEIAPELLVKHQAAGKAKSLAQKYPDALIIGSDQVFVDASGRVLGKPDSLEGAVRQLRGMAGKSHTFYTGLSVYDSNRDETLTGFATYRVTLRALTEQEIRCYLQRENPLDCAGSFKVEGLGIALMQRLEGDDYTTLIGLPLIKLVDFLGHFGVRVLGDQA
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP).  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
7-methyl-GTP pyrophosphatase, m(7)GTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YceF subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGR_LACDB
Sequence: MNYKERRQLIYELIQTNKIETQEQLLLLLQAHGANATQATISRDIRALHISKVPDDDGRSYYVKAPSAAVNRERQLKDAIRERVATVTAVQFTVVIQTSMKLTYAPILAGLIDDIDNDDVVGTIAGTDTLLVILKDAEAAASFADWAQAIVKERKIY
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2009_MYCBO
Sequence: MAGLNIYVRRWRTALHATVSALIVAILGLAITPVASAATARATLSVTSTWQTGFIARFTITNSSTAPLTDWKLEFDLPAGESVLHTWNSTVARSGTHYVLSPANWNRIIAPGGSATGGLRGGLTGSYSPPSSCLLNGQYPCT
What are the official names of this protein?
Uncharacterized protein Mb2009.
Protein: GUAA_BACAN
Sequence: MKKQHDTIIVLDFGSQYNQLIARRIREFGVYSELHPHTITAEEIKAMNPKGIIFSGGPNSVYGEGALHCDEKIFDLGLPIFGICYGMQLMTQQFGGTVERANHREYGKAVLKVENESKLYANLPEEQVVWMSHGDLVTGLPEGFVVDATSESCPIAGMSNEAKNLYGVQFHPEVRHSEHGNDLIKNFVFGVCGCSEGWNMENFIEVELEKIRETVGDKKVLCALSGGVDSSVVAVLIHKAIGDQLTCIFVDHGLLRKGEAEGVMKTFSEGFHMNVIKVDAKERFMNKLKGVEDPEQKRKIIGNEFIYVFDDEASKLEGMDFLAQGTLYTDIVESGTATAQTIKSHHNVGGLPEDMQFKLIEPLNTLFKDEVRVLGSELGIPDEIVWRQPFPGPGLGIRVLGEITEEKLEIVRESDAILREEIIKAGLDREIWQYFTALPGMRSVGVMGDERTYDYTVGIRAVTSIDGMTADWARIPWDVLEKISVRIVNEVKHVNRIVYDVTSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: GATB_LISW6
Sequence: MNFETVIGLEVHVELKTNSKIFSSAPAHFGAEPNTNTTVVDLGMPGVLPVLNKRAVEYGMKAAMAINCEIAEHTKFDRKNYFYPDNPKAYQISQFDKPIGEHGWIEIEVGGKKKKIGITRLHLEEDAGKNTHTSHGYSLVDINRQGTPLIEIVSEPDIRSAEEAYAYLEKLKSIIQYTGVSDVKMEEGSMRCDANISIRPIGQEAFGVKTELKNLNSFNNVRKGIEYEEKRQAEVLLSGGIIEQETRRFEEATGKTSLMRIKEGSDDYRYFPEPDLVDLFIDDAWKERIRAEIPELPDKRQIRYINDLGLPAYDAMVLTLTKEMSDFFEATLAARADAKQASNWLMGEVSAYLNAEQKELNETGLTPENLAGMIKLIEAGTISSKIAKKVFRELAQNGGDAEQVVKDKGLVQISDEGALRTIIGEILDNNEQSITDYKNGKDRAVGFLVGQVMKATKGQANPPMVNKLLLEEMNKR
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: RPOA_CLOK1
Sequence: MLEIEKPKIECVETSEDGNYGKFVVEPLERGYGTTLGNALRRILLSSLPGVAASHVKIDGVLHEFSTVRGVKEDVSELILNIKELALKMNGDGTKTIYIDAQGPGEVVAGDIKTDGDVEIINGELHIATLDENSRLYMEITVNGGRGYVSQRRNKFEDMPIGTIPVDSIYTPIKRVNFNVENTRVGQITDYDKLSLEVWTNGTILPDEAVSLSAKILIEHFKLFMTLTDHANNVEIMVEKEEDKKEKVLEMAIEELDLSVRSYNCLKRAGINTVQELTERTMDDMMKVRNLGKKSLEEVEQKLDTLGLSLKQNED
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: RPOE_ECOL6
Sequence: MSEQLTDQVLVERVQKGDQKAFNLLVVRYQHKVASLVSRYVPSGDVPDVVQEAFIKAYRALDSFRGDSAFYTWLYRIAVNTAKNYLVAQGRRPPSSDVDAIEAENFESGGALKEISNPENLMLSEELRQIVFRTIESLPEDLRMAITLRELDGLSYEEIAAIMDCPVGTVRSRIFRAREAIDNKVQPLIRR
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase (RNAP) to specific initiation sites and are then released.  Extracytoplasmic function (ECF) sigma-E controls the envelope stress response, responding to periplasmic protein stress, increased levels of periplasmic lipopolysaccharide (LPS) as well as heat shock and oxidative stress; it controls protein processing in the extracytoplasmic compartment (By similarity).
What are the official names of this protein?
ECF RNA polymerase sigma-E factor, RNA polymerase sigma-E factor, Sigma-24.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. ECF subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associates with the inner membrane via RseA.
Protein: NRFA_VIBVY
Sequence: MSIKHWMASSVSVTALVMTALLNITAVSAEEKGLVDPRNDAFEQNHPDQYQSWKKTSESVEIEDALAEDPNMVILWAGYGFAKDYNKARGHFYALDDVRQTLRTGGPQDAKSGPMPMACWSCKSPDVARVIDERGEDGYFEGKWARLGAEIANPIGCADCHDTRSEKFKNGEPELALTRPYVERAFQAINKPFEQQSRLDKQASVCAQCHVEYYFTGPTKAVKFPWDMGTGVQQMEEYYDALGFADWTHAVSKAPMLKAQHPGFETWREGIHGKNKVVCVDCHMPKVKKEDGTVYTDHKVGNPFDRFEDTCAQCHTQSKDQLREIVSTRKAQVLNMKLTAEKQIVAAHFEAGAAWKAGATEEEMKPILQDIRHAQWRWDYAIASHGVHMHAPEVALEVLGTAVDRAADARTKLVRLLATKGITEPVQIPDISTKAAAQKALGMDMEKMNAEKQHFLKTVVPDWDKAAAERESKY
What is the function of this protein?
Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process.
What are the official names of this protein?
Cytochrome c-552, Ammonia-forming cytochrome c nitrite reductase, Cytochrome c nitrite reductase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c-552 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: HOPM1_PSEU2
Sequence: MIGTRVGGSGSTEIVQANQPQPSAAVAQAHPHAVSPSSNPPLTASQSAAQAPESSAAGAARLPVAPRHLPTLEKFRAEQPTVQGTSTPTISANAALLIGSLLQSEKLPFEVMAARLSPERYALQQFHGSDLQQMLGRFAEPGHLPGKAETEQLIKGFARSLADQLEHFQLMHDATAEAFGPGGLRDRNTLAVSQAALGEYAGRASKSIEAGLNHSLAVLDERIAALDSQLEGATEDSRPVLLMDRQALETARAMLSDLHVDFCKSPEAKRLSAVAAHTQMDALIDKLNVDRSSVGGWKGIGPIVAAAVPQFMVSMLHLGYIRTATSDAMKDAVPEKSADASMKRALAVGLTAGVAHEGVTNLLKPMVQAGFQKAGLNERLNMVPLKGIDTDSVIPDPFELKNDNGALVRKTPEEAAEDKAFVASERAVLNQKKVQVSSTHPLGEMIPYGAFGGGQAVRQMLNDFNLLNGQTLSARAVTSGIAGAISATTQTIAQLNSTYVDPRGRKIPVFTPDRANADLGKDLAKGLDLREPAVRTAFYSKAVSGVQSAALNGALPSVAVQPQGASGTLSAGNIMRNMALAATGSVSYLSTLYANQSVTAEAKALKEAGMGGATPMVARTETALSNIRHPDRASLPHTFQPDTLGGVPRAVENAYHMARGALQLPTQVVVDTVRVVEDGVASGVSSLRDAHKPAETSSPTADDAAAVELTAMEEGRRR
What is the function of this protein?
Involved in the suppression of basal resistance and promotion of disease symptoms in plants.  May be involved in the inhibition of a host vesicle trafficking pathway (By similarity).
What are the official names of this protein?
Effector protein hopM1, Hrp outer protein M1, Type III effector hopPtoM.
What are the subcellular locations of this protein?
Secreted. Host membrane. Note=Secreted via the type III secretion system (TTSS). Localized to the plant endomembrane (By similarity).
Protein: GNL3L_MOUSE
Sequence: MMKIRHKNKKPGKGSKGCKKPARQNGKKVTSRPSSAPQIVHGNDHASREAELKKKRVEEMREKQQVAREQERQRHRTMESYCQDVLKRQQEFEQKEEVLQELNMFPQLDDEATRKAYYKEFRKVVEYSDVILEVLDARDPLGCRCFQMEETVLRAEGNKKLVLVLNKIDLVPKEIVEKWLEYLLNELPTVAFKASTQHHQVKNLTRCKVPVDQASESLLKSRACFGAENLMRVLGNYCRLGEVRGHIRVGVVGLPNVGKSSLINSLKRSRACSVGAVPGVTKFMQEVYLDKFIRLLDAPGIVPGPNSEVGTILRNCIHVQKLADPVTPVETILQRCNLEEISSYYGVSGFQTTEHFLTAVAHRLGKKKKGGVYSQEQAAKAVLADWVSGKISFYTLPPPTHTLPTHLSAEIVKEMTEVFDIEDTEHANEDTMECLAVGESDELLGDMDPQEMEVRWLHSPLVKIADAIENRSTVYKIGNLTGYCTKPNRNQMGWPKRNVDHHCPQNNRVVEVSSVDRRPMLQRILETDPLQQGQALASALKNKKKLQKRSDKIATKLSDSMMSMLDLSGNSDDCAGD
What is the function of this protein?
Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML.  Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation.  Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase.  Required for cell proliferation.  By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition.  Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation.  By acting on MDM2, may affect TP53 activity.  Required for normal processing of ribosomal pre-rRNA.  Binds GTP (By similarity).
What are the official names of this protein?
Guanine nucleotide-binding protein-like 3-like protein.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family.
Protein: RL25_CHLMU
Sequence: MELVVQSRETDKKSVIKKIRQQGGIPAVLYSGGKSLANVVIDARVFNKFLSTLESGALASTVFTLSYEGREIKALVKDIQYHVTTYDVIHLDFEELVEDREVRLNIPIRCINTVDCVGVKLGGSLRQVIRYMRVVCKPKDIVPFLELDVQSLGLSQTLKLSDIRIPEGIKPVTPLKEVAVTVARR
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: SFSA_ACET2
Sequence: MRIEGELVKAKFVKRLNRFVALVEVDGVQEFAHVPNTGRLKELLVDGAAVMVRKYDKTDRKTRFGLILVRKNGIWVSIDSANAPNRIMYEALVQGKFDKFRDYSEIRREVTVLNSRFDFGLFSEGKEYYIEVKGVTLVENRQGFFPDAPTQRGTRHLEELTKIRQNGKEAGVAFIVQREDADVVRPNDRTDKNFANALRIAAEAGVDLMAYVCKVDAEQRRMDIVREIPVIIK
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: RS7_PROMS
Sequence: MSRRNAAVKRPVLPDPQFNSRLASMMISRLMKHGKKSTAQRILSDAFSLISERTGGNAVELFETAVKNATPLVEVRARRVGGATYQVPMEVRQERGTAMALRWLVTFSRARNGKSMSQKLAGELMDAANETGSSVKKREDTHKMAEANKAFAHYRY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: EFM7_ASPFU
Sequence: MANEEDFVGFGDTFKDPEGFYPPEKEPTFAEHQMLSGQTVRVRLVGSHPLYGDLLWNAGRTSATYIEEKASSLVEGKDVLEVGAAAGVPSIVSAVKGARTVVMTDYPDPDLVENMRYNASLSAAIIPSSSSLHVAGYKWGDPVEPLTAYLPEGSNSFDLLIMADVVYSYQEHPNLIKVMQKALKKSKDSVALVVFTPYQPWLLPRNQTFFPLAEQNGFQVTKIFEKVMDKVLFENDPGDELLRRTVFGYEIRWAPNQLN
What is the function of this protein?
S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono- and dimethylation of 'Lys-3'.
What are the official names of this protein?
Protein N-terminal and lysine N-methyltransferase efm7, Elongation factor methyltransferase 7.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM7 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OGG1_SULIA
Sequence: MLRSLVQNPRVRARVLERVDEFRLNNLSNEEVWFRELTLCLLTANSSFISAYQALNCLGDKIYYANEEVIRSILKSCKYRFYNLKAKYIIMAREKVYGKLKEEITPLADSDQQLAREKLLNIKGIGMKEASHFLRNVGYFDLAIIDRHLIDFMRRIGAIGETNVKHLSKSRYISLESVLKSIALNLNISVGILDLFIWYKETNTIVK
What is the function of this protein?
Catalyzes the excision of an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 8-oxoG) from DNA.  Also cleaves the DNA backbone at apurinic/apyrimidinic sites (AP sites).
What are the official names of this protein?
8-oxoguanine DNA glycosylase/AP lyase.
What is the protein family that this protein belongs to?
Belongs to the type-2 OGG1 family.
Protein: ILVC_BRASO
Sequence: MRVYYDRDADLNLIKGKKVVIVGYGSQGHAHALNLKDSGVKDVAIALRKGSASAKKAEGAGFKVMEVAEAAKWADLVMMLTPDELQGDIYREHLHDNMKQGAALVFAHGLNVHFNLLDPRADLDVLMIAPKGPGHTVRSEYQRGGGVPCLIAIAKDSSGNAHDLGLSYASAIGGGRAGIIETTFKEECETDLFGEQAVLCGGLVELIKAGYETLTEAGYAPEMAYFECLHEVKLIVDLIYEGGIANMNYSISNTAEYGEYVTGPRIITPETKAEMKRVLDDIQSGRFARDWMLENKVNQSSFKATRARLSQHPIEEVGARLRDMMPWIKKGALVDKSKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: MURD_BARQU
Sequence: MISCTCYKGQKVALFGLGKSGLAAAQALMSGGAKVVAWDDNPSGVHTAKRENIPTRDLQYENWSEFVALILAPGVPLTYPQPHWVVDKARQADIEIVGDIELFVRARNHFLQHSGFRDQDVPFIAITGTNGKSTTTALLAHLLEQMGYDVQMGGNIGTAILTLKPFVKKRIYVIECSSFQIELTPSLQPTIGLLLNLTSDHIDRHGSFAAYVQAKRRLVTGASYAFISVDNAVCQALYQQLLDEGHQVGAVSKEHFVENGFYADRTKLFSVCQGQRHMLADLADMTALRGSHNAQNALMVLATLQALKISDPHIEKYLASYKGLAHRMQQVRKMGPVLFINDSKATNAEASAPALSTFNDIFWIVGGQAKEGGIEALRGFFHKIRKAYLIGEAAQEFAGVIGSAFPFSMSLTLENAVHEATVDAMCCKAKEAVVLFSPACASYDQFKNYEVRGEAFVSFVMQLKES
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYV_EHRRW
Sequence: MQSLFSNKYKFKDTEEKLNAYWDKIKLYKWKNLQGKQFIIDTPPPTISGQLHIGHVFSYCHTDFIARYQRMLGKDVLYPIGFDDNGLPTERLVEKIKKVRAADIDRKEFKALCNEVSAKFRMEFKILFQSLGISYDWDLEYHTISEEIQKLSQMSFIALYNMGKIYRKLQPIFWDCADRTAIARVEVEEKEMSSFMSTIAFSTEAGELINIATTRPELMPACVALFFNPLDIRYQHLQGQYAIVPIFGNKVPILSDEQVKIDKGTGLVMCCTFGDELDVYWWNKHNLNTQIIISKSGTLDLKHNIAETDTLSGKLHGVSIVEARKLVLETLSKCNLLIKKEEILHNVKCAERSGMPIEILLSNQWFIKVVEIKHELLEQVRKINWYPQSMRKQIEMWIDGLNWDWCISRQRYFGIPFPVWYSKRDNEEIIIPDVNELPIDPTETLPQGYSKEEVEADVDVMDTWATSSLSPQFNSIHTGINSIPLIPASLRAQSHEIIRSWAFYTILQAYYHHNSIPWENIMVSGWCLAADKSKMSKSKGNALIPNQLLQEYGADVIRYWAANSRLGSDTVFSDEVLQLGKRLVTKLWNASKFVSMFVSQCQIPDLNCVTETMDKWVLTKLYKVIVKATESFNVFEYCVALDYIESFFWKDFCDNYLELVKKRAYGESVTNKENLSAVNTLSFVLMALLKMLAPFMPYITEEIYSTLYNNGSIHDHDNWPVVNTSLCNEMDEQLGEDFIEILNQVRKIKANAQLSVKCKIYKLIINSENYDFPTSWENDLKAVCNAEHIVQDKRTSYYNDKFLISVQFAN
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LDHA_HUMAN
Sequence: MATLKDQLIYNLLKEEQTPQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLRTPKIVSGKDYNVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPNCKLLIVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDSSVPVWSGMNVAGVSLKTLHPDLGTDKDKEQWKEVHKQVVESAYEVIKLKGYTSWAIGLSVADLAESIMKNLRRVHPVSTMIKGLYGIKDDVFLSVPCILGQNGISDLVKVTLTSEEEARLKKSADTLWGIQKELQF
What is the function of this protein?
Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+).
What are the official names of this protein?
L-lactate dehydrogenase A chain, LDH-A, Cell proliferation-inducing gene 19 protein, LDH muscle subunit, LDH-M, Renal carcinoma antigen NY-REN-59.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
Protein: SYD_BUCAI
Sequence: MRTKYCGNIRISHVNKKVKLCGWVHKVRNLGQFIFVDMRDYTGLVQVIFELKNYKIFKKALNLRNEFCIQVFGTVQKREKKNQNIKIRTGEIEILANVLNILNTSKSLPLNFTQENNDDSRLKYRYLDLRSFDILENLKIRNKITYLIRNFMTKKNFLDIETPILTKSTPEGARDYLVPSRNHYGKFYALPQSPQLFKQILMISGIDRYYQIVKCFRDEDLRSDRQPEFTQIDIEVSFMSAKKIRNLVENLIKKLWLEIRNINLKKFPQISFHEAMKKYGSDKPDLRNPIEIIDVSNIFKDKKFISFFNLNPQKNNRIALLCISKGAHLSRKKIDDYTKYVQRFDAKKLFYMKIKECKLGCLGIHSSIKNILDEIILKEIIEKSQSKNGDILFLIADQEHIVNKSLGMLRLKIGIDLNITKKNRWEPLWIVNFPMFDKDIQGNLSSVHHPFTAVKNMDREILKNSPDLAISDSYDLIINGYEIGGGSVRIHDVNMQKQVFDIIGIKKSMQNEKFGFLIEALKYGAPPHAGIALGLDRIVMLLTNSKNIRDVIAFPKTTSATCLMTNSPSTVDNLLLQELAIKHLKK
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS9_SHEB5
Sequence: MAATQYYGTGRRKTSTARVFAKAGSGNIVVNQRPLDQYFGRETARMVVRQPLELVEMTDKLDIYVTVKGGGITGQAGAIRHGITRALMQLDEALRPSLRSAGFVTRDARKVERKKVGLRKARRKPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.