PharMolix/UniProtQA huggingface dataset:
Protein: TA2R8_GORGO
Sequence: MFSPADNIFIILITGEFILGILGNGYIALVNWIDWIKKKKISTIDYILTNLVISRICLISVMVVNGIVIAVYPDVYTKSKLQIAICTFWTFANYLNMWITTCLNVFYFLKIANSSHPLFLWLKQKIDMVVRWILLGCFAISLLVSLIAAIVLSYDYRFHAIAKHKRNITEMFHVSKRPYFEPLTLFNLFAIVPFIVSLISFFLLVRSLWRHTKQIKLYATGGRDPSTEVHVRAIKTMTSFIFLFFLYYISSILVTFSYLMTKYKLAVEFGEIVAILYPLGHSLILIVLNNKLRQTFVRMLTCRKIACVI
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 8, T2R8.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS9_GEOUR
Sequence: MAAASFYGTGKRKSSIARVWLKPGTGVITVNHKTLDEYFGRETSKMVVKQPLELTENMGKFDIYVTVCGGGDSGQAGAIKHGITKALLEVDAALRGTLKKAGFVTRDSRIKERKKYGKKAARASFQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: DEF_VIGUN
Sequence: MEKKSIAGLCFLFLVLFVAQEVVVQSEAKTCENLVDTYRGPCFTTGSCDDHCKNKEHLLSGRCRDDVRCWCTRNC
What is the function of this protein?
This protein is required for germination.
What are the official names of this protein?
Defensin-like protein, 10 kDa protein, Clone PSAS10.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYH_VIBCH
Sequence: MAKTIQAIRGMNDCLPTQSPLWQKVEGVVKNVISAYGYSEVRMPIVEMTHLFSRAIGEVTDVVEKEMYTFEDRNGDSLTLRPEGTAGCVRSGIENGLLYNQEQRLWYMGPMFRHERPQKGRYRQFHQCGVEVFGLDGPDVDAELIMMTARLWRELGIAQHVRLELNSIGSLEARANYRTALIDYLEQYQNVLDEDCKRRMYTNPLRVLDSKNPDVQAILGDAPQLSDYLDAESKQHFAGLCELLDAAGIEYTVNQRLVRGLDYYNRTVFEWITESLGSQGTVCGGGRYDGLVEQLGGKPTPAVGFAMGLERLVLMMETLGNTDVRRSVDVYMVTAGEGTMMAGMKLAEQLREQVPGLRVMTHFGGGNFKKQFKRADKVGAAIALVLGEDEVAAQTVVVKDLAGGEQNTVAQAEVAKLLAHLA
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_PORG3
Sequence: MSRIGKLPISIPAGVTVSHKDEIVTVKGPKGELSQYVDPRITVVIEGGMIHLERKTDDRIERSLHGLYRSLINNMVQGVSAGFKRELELVGVGYRASNQGQLLELSLGFTHSIFMQLPKEVTVETKSERNKNPLIILESADKQLLGQVCMKIRSFRKPEPYKGKGVKFVGEQIRRKSGKSAGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RL28_PAEAT
Sequence: MAAHCQVTGAEPGFGHSISHSHRRNKRRFDPNIQKKRYWVPSLRRNVTLTLSARGIKTIDVRGIDSVVADILARGVKL
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: UBIC_BORBR
Sequence: MTTPIPLARGWLPAAPSTLDPLRKYWLFRPGALTAGLRQLGHVRLRVLAEYPTGAPRDEADGMRIAAQSPVWVREVLMSIDGVDSVVARSLTPLRASHGVWQGMRRLLTRPLADMLYHDPGIHRSVFVCRRLAAGVPFHATAIARAPAGGPEPALWARRSAFWRAGQPLLVAECFLPAFWSLARAPVAPR
What is the function of this protein?
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
What are the official names of this protein?
Probable chorismate pyruvate-lyase, CL, CPL.
What is the protein family that this protein belongs to?
Belongs to the UbiC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUC_LIMF3
Sequence: MAKTLFDKVWDKHVIAGKKGDPQLLYVDLHLIHEVTSPQPFDGLRQAGRKLRRPDKTFATIDHNVPTAPTPVTSVESVMDQISKLQITTLQKNCRDFGVELADIGDKDQGIVHVIGPQLGLTQPGKLIVCGDSHTSTHGGLGALSFGIGTSEIEHVFSTQTLWQVKPKNLGVHVTGHLAPGIFAKDIVMALIAKYGTNFAEGYALEYYGPTIDEMPIENRMTLTNMIIEGGAKVAMINPDQKTFDYLRGRERVPKDFDKAVEYWKQFKTDSPDAYDWIIELDVSDLAPYVSWGTTPSMSVPYGAKLPAVTDKNIERAYDYMDLEPEMPVQDIPINWVFIGSCTNGRLSDLKEAARVMKGKHLAPGVQAWVVPGSRGVQKAAEKIGLDKIFTDAGCEWRDPGCSACLAMNPDKVPAGMHCASTTNRNFEGRQGPGTRTHMASPAMVAAAGINGHFVDVRKFYQGEA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: PTH_RHIE6
Sequence: MLIIAGLGNPGAKYAGNRHNIGFMAVDAIHRRQSFSPWSKKFKAEIAEGELGGEKVLLIKPQTYMNLSGEAVGEAMRFYKLQPADLVAIYDELDLSPGKARLKTGGGHGGHNGIRSLDAHCGKEYRRLRLGIGHPGIKEMVQNHVLGDFAKADSDWLEPLLETLADNAEMLVRNEDSQLMNKIALALGGKAEEEKPRKEGKDGEKKPAGQSHIRQARSSNQPKLPATGPMAEMLKKMFGNKGE
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACHG_MOUSE
Sequence: MQGGQRPHLLLLLLAVCLGAQSRNQEERLLADLMRNYDPHLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLRWDPKDYEGLWILRVPSTMVWRPDIVLENNVDGVFEVALYCNVLVSPDGCIYWLPPAIFRSSCSISVTYFPFDWQNCSLIFQSQTYSTSEINLQLSQEDGQAIEWIFIDPEAFTENGEWAIRHRPAKMLLDSVAPAEEAGHQKVVFYLLIQRKPLFYVINIIAPCVLISSVAILIYFLPAKAGGQKCTVATNVLLAQTVFLFLVAKKVPETSQAVPLISKYLTFLMVVTILIVVNSVVVLNVSLRSPHTHSMARGVRKLFLRLLPQLLRMHVRPLAPAAVQDARFRLQNGSSSGWPIMAREEGDLCLPRSELLFRQRQRNGLVQAVLEKLENGPEVRQSQEFCGSLKQASPAIQACVDACNLMARARRQQSHFDSGNEEWLLVGRVLDRVCFLAMLSLFICGTAGIFLMAHYNQVPDLPFPGDPRPYLPLPD
What is the function of this protein?
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
What are the official names of this protein?
Acetylcholine receptor subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Gamma/CHRNG sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: PYRH_DESPS
Sequence: MRFIMPIKYKRMLLKLSGEALMGKDSYGINTGVLEFVAGEIKELVAMGVELGVVVGAGNIFRGMAGASKGMDRATADNMGMLATVMNSLAMQDALERSGVITRAMSAIPMQSICESYIRRRATRHLEKGRVVIFAAGTGNPYFTTDSAGVLRALEIDADIVVKATKVDGVYDKDPMIHDDAVKFEHLTYDDVLRKGLKVMDAAGIALAKDDDKPIMVLNMSVAGNMKKAALGERVGTLITA
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TATA_RICPU
Sequence: MGMSFSHLLIVLLIIFVLFGAGKLPQVMSDLAKGLKAFKDGMKDDGSDNDNDKNK
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RIBZ_CLOD6
Sequence: MKQKWIVLIIICIGVFMSTLDGSILNIANPTIAADFKINMSQIQWVVTAYMLVVTATMLFFGKLGDKVGSNRLYTLGFFIFTIGSFLCSMSNNLSTLISSRIFQAVGASILMATGLGIVSNAFPANEKGKAIGITGAVVGIGNMSGPVIGGIILEHFGWPSIFIINIPIGIIAVFLGIKFLPKPVLDEQNKSFDIPGLLLFASCTTLILLAMNEKGNTRLYLGITALIIFLLLALREVKFEQSFIDLPLFKNRNFTVGNIIGVACYFPQMAVSFLLPFYLEQLKNLSPMMAGYVMTVHPLIMVLIAPIAGSLSDKHGAKNILTASFSFMTISLVGMALLKADSPLYLLIVCLVIFGLGLGAFSSPNNSSILADVPPQKQGYGGSFLATIRNLSFALGTAFFSSFFAQSLTYNQKFKSHTSAYVIASNQSYWIAASVCFIGLILTVFFMRKTDKSIS
What is the function of this protein?
Transports riboflavin into the cell.
What are the official names of this protein?
Riboflavin transporter RibZ.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BIOF_HYDCU
Sequence: MAIESIKNRFAPVLAKREAEALYRRRPLVTSPQTAEMQINGLQVINFSSNDYLGLANHPALKHSCETIQDLSYGSGAAHLVTGHHLEHHLLEDELADWLGCERALLFSTGYMANLAVQQTLMQKGDWILADKLNHASLIDGARYSEADLKRYPHLDMQALEKRLQKAQQENRQCLIVTDGVFSMDGDCAPLQTIQALAKTYQAWLFLDDAHGFGTLGEQGKGTLAHFNLTPDENTIIMGTLGKAFGASGAFVAGSEVLVETLIQMARPYIYTTAMPPINARVARTALKQVQQADAEREQLKRNIQHFQTGANQLGLTLWPSDSAIQPIMLGRSAQAIQWSEALKQKGLWVTAIRPPTVPKNTARLRVTLSAAHTAEHIEKLLQALAQCQDDFPSSNT
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: IF1A2_HALSA
Sequence: MSDESGRRNLRMPNDDEVFAVVKRHDGGNHVTLQCEDGKERMGRIPGRMKYRTWINEGDVVLAEPWDWQDEKANVEWRYSDQDADQLREEGHIE
What is the function of this protein?
Seems to be required for maximal rate of protein biosynthesis.  Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity).
What are the official names of this protein?
Translation initiation factor 1A 2, aIF-1A 2.
What is the protein family that this protein belongs to?
Belongs to the eIF-1A family.
Protein: RPOZ_RHOPB
Sequence: MARVTVEDCIDKVDNRFDLVLLAAHRARMISSGSQLTIDRDNDKNPVVSLREIAEETISPEDLREELVHSLQKFVEVDEPEPDTVPLIGSAGASVDADDTEVAPERMTEEELLKGLEGLAPPEEQPEEDE
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: MTC6_CANAL
Sequence: MTSLLFAFSLFLSFSVGSIFPFSISNGPAVNDTLQNAIRSQRDVSKPIPIDRVGFSGVSLSLFFESEGYSSDSLSNLNGLLKENVDGVMIDLYWNEFTSKWQLCPAPFPNNITYTTASNRIVDVSWNNKTYKCDPNLSTDNIMSILNSFIRDTNTDVEANFMHVMYNLKSIHYEKSNQTISLENIYKEKNSNLNVVGMDTLNDTVSLLSSYIFTPTLLKQYQSTSNKYTNSSSSIRYIDSLNETQAIQDFYSQSTILMPSLQTVLLTQYKRLMVHVVTNDMAESSRSYQISSSDKDTIFFNSDLPASIFHTDNASADELCYELSDAYNGTDVNIAEFNKVSLNATLRLVVDDDKTPFTTKSLSKYVRCGYCPIFNSTEYSSQKVTEGNSSIISREFASNLFWSWAPGQPSGPDNCINCTRPTTNNTSKHSDDNGEEEEEGNNIAYKCVALTEEGWEVSNCYEKYLFACQNKLSRNEWKLNNSTKRNYFDIDDDDCPEGYFFSLPRSNIEMLSLMTTVKQENVNYPIWIDLNDITVENCFVSGGPYAQCPYQETVTTDKFVRMIAPSFVVAMVVLVLIFIEKVFRKTPIQTNRKRYWKKAIHEYYAKNDYEGVPS
What is the function of this protein?
May be involved in telomere capping.
What are the official names of this protein?
Maintenance of telomere capping protein 6.
What is the protein family that this protein belongs to?
Belongs to the MTC6 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: VSP2_ARATH
Sequence: MKILSLSLLLLLAATVSASVPGLIELVDSKTIFGNVAELLEKEKLSINYANCRSWHLGVETSNIIDFDTVPANCKDYVEDYLITSKQYQYDSKTVCKEAYFYAKGLALKNDTVNVWIFDLDDTLLSSIPYYAKYGYGTEKTDPGAYWLWLGTGASTPGLPEALHLYQNIIELGIEPIILSDRWKLWKNVTLDNLEAAGVTYWKHLILKPNGSNLRQVVYKSKVRKSLVKKGYNIVGNIGDQWADLVEDTPGRVFKLPNPLYYVPS
What is the function of this protein?
May function as somatic storage protein during early seedling development.
What are the official names of this protein?
Vegetative storage protein 2.
What is the protein family that this protein belongs to?
Belongs to the APS1/VSP family.
Protein: RECO_STREM
Sequence: MRIQRSLGIVLYNKNYREDDKLVKIFTEAAGKRMFFVKHIGRSKLAPVVQPLTAADFLLKINDSSLSYIEDYNQVEAYRHINEDFFRLSYASYVLALADAAIPDNEPDPQLFAFLKKTLDLIEEGLDYDILTNIFEIQILDRFGVRMNFHDCVFCHSTNLPFDFSHKYSGVLCPQHYHEDEGRYGLDPNVIYLINRFQTINIDELKTISVNADMKKKLRLFIDALYEDYVGIRLKSKVFIDDLAKWGDIMKNKQGL
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: TRMB_CHLFF
Sequence: MKPQDLKVPFFWEERSTKIKDNVLYVPEHYFKHHQFIMPSWEEFFGNDNPISCELCSGNGDWVVAQAKETPEVNWIAVEKRFDRVRKIWSKMHNCRVTNLRIVCGDAQTFFLHYLGEAVVQRIIVNFPDPWPKSRHRKHRLFQDEFLNNVVRVLTEPGILILATDDKNYLLQAIQIMRQYLSPTMEDPYYCEVENYGNSWFETLWRSKGREIFYTEFVKKLGYS
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: THII_PSEFS
Sequence: MKLIVKVFPEITIKSRPVRTRFIRQLAKNIRAVLRDLDPAVVVNGVWDNLELETRITEPKALKDMTERLSCMPGIAHFLQVDEYPLGDFDDITEKCKQHYGQSLEGKIFSVRCKRAGKHTFSSMDVEKYVGSKLRRECGAAGISLKAPQIEVRMEIRDQRLFVIHSQHDSIGGYPLGALEQTLVLMSGGFDSTVAAYQIMRRGLMSHFCFFNLGGRAHELGVMEVAHFIWKKYGSSQRVLFVSVPFEEVLGEILGKVDNSHMGVVLKRMMLRAASRIADQLQIDALVTGEAISQVSSQTLPNLSLIDCVTEKLVLRPLIASHKQDIIDLAEEIGTADFAKHMPEYCGVISVNPKTHAKRNRVEYEEQQFDMAILERALENAKLVPIDRVIDELGQDVQIEEVSEALAGQIVVDIRHPDAAEDEPLEIAGIDVQTLPFYALNARFKELDNSRQYLLYCDKGVMSRLHAHHLLSEGYANVRVYRPS
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMH_SHIDS
Sequence: MRQTKTGILLANLGTPDSPTPEAVKRYLKQFLSDRRVVDTSRLLWWPLLRGVILPLRSPRVAKLYASVWMEGGSPLMVYSRQQQQALAQRLPETPVALGMSYGSPSLESAVDELLAEHVDHIVVLPLYPQFSCSTVGAVWDELARILARKRSIPGISFIRDYADNHDYINALANSVRASFAKHGEPDLLLLSYHGIPQRYADEGDDYPQRCRTTTRELASALGMAPEKVMMTFQSRFGREPWLMPYTDETLKMLGEKGVGHIQVMCPGFAADCLETLEEIAEQNREVFLGAGGKKYEYIPALNATPEHIEMMANLVAAYR
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRP6_YEAST
Sequence: MTSENPDVLLSRVINVVRAASSLASQDVDFYKNLDRGFSKDLKSKADKLADMANEIILSIDEHHESFELKEEDISDLWNNFGNIMDNLLEMSDHSLDKLNCAINSKSRGSDLQYLGEFSGKNFSPTKRVEKPQLKFKSPIDNSESHPFIPLLKEKPNALKPLSESLRLVDDDENNPSHYPHPYEYEIDHQEYSPEILQIREEIPSKSWDDSVPIWVDTSTELESMLEDLKNTKEIAVDLEHHDYRSYYGIVCLMQISTRERDYLVDTLKLRENLHILNEVFTNPSIVKVFHGAFMDIIWLQRDLGLYVVGLFDTYHASKAIGLPRHSLAYLLENFANFKTSKKYQLADWRIRPLSKPMTAYARADTHFLLNIYDQLRNKLIESNKLAGVLYESRNVAKRRFEYSKYRPLTPSSEVYSPIEKESPWKILMYQYNIPPEREVLVRELYQWRDLIARRDDESPRFVMPNQLLAALVAYTPTDVIGVVSLTNGVTEHVRQNAKLLANLIRDALRNIKNTNEEATPIPSSETKADGILLETISVPQIRDVMERFSVLCNSNISKSRAKPVTNSSILLGKILPREEHDIAYSKDGLPNKVKTEDIRIRAQNFKSALANLEDIIFEIEKPLVVPVKLEEIKTVDPASAPNHSPEIDNLDDLVVLKKKNIQKKQPAKEKGVTEKDAVDYSKIPNILSNKPGQNNRQQKKRRFDPSSSDSNGPRAAKKRRPAAKGKNLSFKR
What is the function of this protein?
Nuclear-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events.  In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and cryptic unstable transcripts (CUTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm.  The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes.  RRP6 has 3'-5' exonuclease activity which is not modulated upon association with Exo-9 suggesting that the complex inner RNA-binding path is not used to access its active site.
What are the official names of this protein?
Exosome complex exonuclease RRP6, Ribosomal RNA-processing protein 6.
What is the protein family that this protein belongs to?
Belongs to the exosome component 10/RRP6 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: VPL_BPP2
Sequence: MMTLIIPRKEAPVSGEGTVVIPQPAGDEPVIKNTFFFPDIDPKRVRERMRLEQTVAPARLREAIKSGMAETNAELYEYREQKIAAGFTRLADVPADDIDGESIKVFYYERAVCAMATASLYERYRGVDASAKGDKKADSIDSTIDELWRDMRWAVARIQGKPRCIVSQI
What is the function of this protein?
Carries out the completion of filled heads by rendering the newly packaged DNA in filled heads resistant to DNase.  The protein is assumed to bind to DNA-filled capsids.
What are the official names of this protein?
Head completion/stabilization protein, GpL.
What is the protein family that this protein belongs to?
To phage HP1 protein ORF20.
Protein: CLCKA_RAT
Sequence: MEELVGLREGSSGKPVTLQELWGPCPRIRRGVRRGLEWLKERLFRVGEDWHFLVALGVLMALISYAMNFAIGRVVRAHKWLYREVGDGHLLRYLSWTVYPVALLSFSSGFSQSISPFSGGSGLPELKTMLSGVVLEDYLDIKNFGAKVVGLSCTLATGSTIFLGKVGPFVHLSVMISAYLGRVRAKTIGETENKAKEIEMLSAAAAVGVATVFAAPFSGVLFSIEVMSSHFSVWNYWRGFFAATCGAFMFRLLGVFNSEQETITSIYKTRFRVDVPFDLPEIFFFVALGFICGVLSCAYLFCQRTFLRFIKTNRYTSRLLATSKPSYAALVALVLASITYPPGVGRFMASRLSMAEHLHSLFDNNSWALMTRNSSPPWPAEPDPQNLWLEWCHPRFTIFGTLAFFLVMKFWMLILATTIPMPAGYFMPIFIIGAAIGRLLGEALSVAFPEGIVAGREVNPIMPGGYALAGAAAFSGAVTHTISTALLAFELTGQIVHALPVLMAVLAANAISQNCQPSFYDGTIMAKKLPYLPWIRGRQIGSYPVTVEHFMNCNLTTLAKDTPLEEVVKVVTSTEVSQYPLVETRESQTLVGIVERTHLVQALQTQPASWAPGQERFLQDILAGGCPTQPVTLQLSPETSLYQAHSLFERLTLQSLFVTSRGKAVGSVSWAELKKAISTLINPPAPK
What is the function of this protein?
Voltage-gated chloride channel.  Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport.  May be important in urinary concentrating mechanisms.
What are the official names of this protein?
Chloride channel protein ClC-Ka, Chloride channel Ka, ClC-K1.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. CLCNKA subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y1796_PELTS
Sequence: MEIKLINIGFGNIVSANRIIAIVSPESAPIKRIITEARDRGMLIDATYGRRTRAVIITDSDHVILSAVQPETVAHRLVSKEAPAQAEESAD
What are the official names of this protein?
Putative regulatory protein PTH_1796.
What is the protein family that this protein belongs to?
Belongs to the RemA family.
Protein: DTD_GEOTN
Sequence: MKAVIQRAKQASVTVNGEVVGAIDAGLVVLLGVTHEDTEADAAYLAEKIAHLRIFEDENGKMNRSLLEVGGAVLSVSQFTLYGDCRKGRRPNFMAAAKPDRALPLYEAFNTFLRGKGIHVETGVFGAMMDVSLTNDGPVTLIIDSGDKPGNE
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FIXC_ECOL6
Sequence: MSEDIFDAIIVGAGLAGSVAALVLAREGAQVLVIERGNSAGAKNVTGGRLYAHSLEHIIPGFADSAPVERLITHEKLAFMTEKSAMTMDYCNGDETSPSQRSYSVLRSKFDAWLMEQAEEAGAQLITGIRVDNLVQRDGKVVGVEADGDVIEAKTVILADGVNSILAEKLGMAKRVKPTDVAVGVKELIELPKSVIEDRFQLQGNQGAACLFAGSPTDGLMGGGFLYTNENTLSLGLVCGLHHLHDAKKSVPQMLEDFKQHPAVAPLIAGGKLVEYSAHVVPEAGINMLPELVGDGVLIAGDAAGMCMNLGFTIRGMDLAIAAGEAAAKTVLSAMKSDDFSKQKLAEYRQHLESGPLRDMRMYQKLPAFLDNPRMFSGYPELAVGVARDLFTIDGSAPELMRKKILRHGKKVGFINLIKDGMKGVTVL
What is the function of this protein?
Could be part of an electron transfer system required for anaerobic carnitine reduction.
What are the official names of this protein?
Protein FixC.
What is the protein family that this protein belongs to?
Belongs to the ETF-QO/FixC family.
Protein: CAS2A_SYNY3
Sequence: MLYLIIYDVPATKAGNKRRTRLFDLLSGYGKWRQFSVFECFLSVKQFAKLQTAMEKLIKLDEDAVCIYVLDENTVQRTITYGTPQPEKPGSIII
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Functions as a ssRNA-specific endoribonuclease.  Involved in the integration of spacer DNA into the CRISPR cassette.
What are the official names of this protein?
CRISPR-associated endoribonuclease Cas2 1.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Protein: RS3A_PYRCJ
Sequence: MAEKQKAVAAQEKVAISKRDPWALKKWFSVYAPPYLGGVFLAEVPAAEAQKLVKRTLEVTLYDITKDISHLPIKLRFQIHRVDGLNASTRFKGLELTRDYLRSLIRRGTSKIMAITDVKTKDGWVMRVAVLGVTTHRVGTAQKSAIRKRFIEVVTKKAAEADIGQFLKEVLEGTLAADLFIAGKKIAPMRKVEVAKIKVLRYPPEEERVAVKEVAAEAAASS
What are the official names of this protein?
30S ribosomal protein S3Ae, Ribosomal protein S1e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.