PharMolix/UniProtQA huggingface dataset:
Protein: LIS1_PONAB
Sequence: MVLSQRQRDELNRAIADYLRSNGYEEAYSVFKKEAELDMNEELDKKYAGLLEKKWTSVIRLQKKVMELESKLNEAKEEFTSGGPLGQKRDPKEWIPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSIQDIPFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR
What is the function of this protein?
Regulatory subunit (beta subunit) of the cytosolic type I platelet-activating factor (PAF) acetylhydrolase (PAF-AH (I)), an enzyme that catalyzes the hydrolyze of the acetyl group at the sn-2 position of PAF and its analogs and participates in PAF inactivation.  Regulates the PAF-AH (I) activity in a catalytic dimer composition-dependent manner (By similarity).  Positively regulates the activity of the minus-end directed microtubule motor protein dynein.  May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end.  Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome.  Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ventricular/subventricular zone toward the cortical plate.  Neuronal migration involves a process called nucleokinesis, whereby migrating cells extend an anterior process into which the nucleus subsequently translocates.  During nucleokinesis dynein at the nuclear surface may translocate the nucleus towards the centrosome by exerting force on centrosomal microtubules.  Also required for proper activation of Rho GTPases and actin polymerization at the leading edge of locomoting cerebellar neurons and postmigratory hippocampal neurons in response to calcium influx triggered via NMDA receptors.  May also play a role in other forms of cell locomotion including the migration of fibroblasts during wound healing.  Required for dynein recruitment to microtubule plus ends and BICD2-bound cargos.  May modulate the Reelin pathway through interaction of the PAF-AH (I) catalytic dimer with VLDLR (By similarity).
What are the official names of this protein?
Platelet-activating factor acetylhydrolase IB subunit alpha, Lissencephaly-1 protein, LIS-1, PAF acetylhydrolase 45 kDa subunit, PAF-AH 45 kDa subunit, PAF-AH alpha, PAFAH alpha.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LIS1/nudF family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Nucleus membrane. Note=Localizes to the plus end of microtubules and to the centrosome. May localize to the nuclear membrane. Redistributes to axons during neuronal development. Also localizes to the microtubules of the manchette in elongating spermatids and to the meiotic spindle in spermatocytes.
Protein: NADK_AERPE
Sequence: MSGAVGLVVKRRSGIAEDVARLVVKELVESGVEVLVDETVDYPSLSGFPRFSISRDPPGRVVVVGGDGTLLRTFLRLGERESPLFMTIKAGKKGFLLDVERYEAVERLRDFLEGRFREVVYPRYRVYLEGEARACMFNDTAVTANNAKMARVHVFVDGDLAMNIDGDGVVVSTTAGSTAYSLSGGGPIIDPRLDVIVLTPLNPVQLFLRSIVVPSGSRVTVEASVYSNPLVVNIDGQYVYELEPGGIVDIERCGSGVRIARFRWWEDYYERLYTRLLAYW
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3654_MAGMM
Sequence: MGQPSWQGDTLHLTIRVQPKAAQERVMGWQGEQLKVALNAPPVDGAANKALCHFLAKQLGIAKGQVTLVRGEKSREKQLVIQGISPSIWQQFLERHGV
What are the official names of this protein?
UPF0235 protein Mmc1_3654.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: RPOA_VIBCH
Sequence: MQGSVTEFLKPRLVDIEQISTTHAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIEGVLHEYSTKEGVQEDILEILLNLKGLAVRVAEGKDEVFITLNKSGSGPVVAGDITHDGDVEIVNPEHVICHLTSDNAAIAMRIKVERGRGYVPASARIHTEEDERPIGRLLVDATFSPVDKIAYSVEAARVEQRTDLDKLVIDMETNGTLEPEEAIRRAATILAEQLDAFVDLRDVRVPEEKEEKPEFDPILLRPVDDLELTVRSANCLKAEAIHYIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLENWPPASIAED
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: PGSB1_DROME
Sequence: MNTSTAISFVAALVLCCLALSANALQIEPRSSWGAVSARSPSRISGAVDYVIIHHSDNPNGCSTSEQCKRMIKNIQSDHKGRRNFSDIGYNFIVAGDGKVYEGRGFGLQGSHSPNYNRKSIGIVFIGNFERSAPSAQMLQNAKDLIELAKQRGYLKDNYTLFGHRQTKATSCPGDALYNEIKTWPHWRQN
What is the function of this protein?
N-acetylmuramyl-L-alanine amidase involved in innate immunity by degrading bacterial peptidoglycans (PGN), preferentially DAP-type PGNs.  Probably plays a scavenger role by digesting biologically active PGN into biologically inactive fragments.
What are the official names of this protein?
Peptidoglycan-recognition protein SB1.
What is the protein family that this protein belongs to?
Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: LPXK_YERPS
Sequence: MIERIWSGQSRLYLLLLPLSWLYGAVTWLIRASYRLGLRSAWRSPVPVIIVGNLTAGGNGKTPVVIWLVEQLQQRGYRVGVVSRGYGGKSAVYPLLLSDNTTTAQAGDEPVLIFQRTGAPVAVSPKRADAIKALLQSHAVDFIITDDGLQHYALQRDFELVVIDGVRRFGNGWWLPAGPMREREGRLRSVDAAITNGGLAAEGEIPMQLVAREAVNLVTGQRQPAEQLQHVVAMAGIGHPPRFFATLNLLGIKPENEHAFADHQDYSLAQLSRLTSGPQILLMTEKDAVKCRAFALPNWWYLPVDAQLPSDRADKLLLNIQALSPDTK
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: FABZ_LISMC
Sequence: MLDIKKIKEILPHRYPFLLVDRVISVEEGKKVTAIKNVTANEEFFNGHFPEYPVMPGVLIVEALAQTSGIAMMQSEANKGKIGLFAGIDGCRFKRQVVPGDQLLLEAEITRMRGAIAKAKVKATVEGDLVCEAEIMFALSDLPK
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOTB_HELPY
Sequence: MAKKNKPTECPAGEKWAVPYADFLSLLLALFIALYAISAVNKSKVEALKTEFIKIFNYAPKPEAMQPVVVIPPDSGKEEEQMASESSKPASQNTETKATIARKGEGSVLEQIDQGSILKLPSNLLFENATSDAINQDMMLYIERIAKIIQKLPKRVHINVRGFTDDTPLVKTRFKSHYELAANRAYRVMKVLIQYGVNPNQLSFSSYGSTNPIAPNDSLENRMKNNRVEIFFSTDANDLSKIHSILDNEFNPHKQQE
What is the function of this protein?
MotA and MotB comprise the stator element of the flagellar motor complex.  Required for the rotation of the flagellar motor.  Might be a linker that fastens the torque-generating machinery to the cell wall (By similarity).
What are the official names of this protein?
Motility protein B, Chemotaxis protein MotB.
What is the protein family that this protein belongs to?
Belongs to the MotB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: ENV_MMTVC
Sequence: MPNHQSGSPTGSSDLLLDGKKQRAHLALRRKRRREMRKINRKVRRMNLAPIKEKTAWQHLQALIFEAEEVLKTSQTPQTSLTLFLALLSVLGPPPVSGESYWAYLPKPPILHPVGWGNTDPIRVLTNQTIYLGGSPDFHGFRNMSGNVHFEEKSDTLPICFSFSFSTPTGCFQVDKQVFLSDTPTVDNNKPGGKGDKRRMWELWLTTLGNSGANTKLVPIKKKLPPKYPHCQIAFKKDAFWEGDESAPPRWLPCAFPDQGVSFSPKGALGLLWDFSLPSPSVDQSDQIKSKKDLFGNYTPPVNKEVHRWYEAGWVEPTWFWENSPKDPNDRDFTALVPHTELFRLVAASRYLILKRPGFQEHEMIPTSACVTYPYVILLGLPQLIDIEKRGSTFHISCSSCRLTNCLDSSAYDYAAIIVKRPPYVLLPVDIGDEPWFDDSAIQTFRYATDLIRAKRFVAAIILGISALIAIITSFAVATTALVKEMQTATFVNNLHRNVTLALSEQRIIDLKLEARLNALEEVVLDLGQDVANLKTRMSTRCHANYDFICVTPLPYNASESWERTKAHLLGIWNDNEISYNIQELTNLIGDMSKQHIDTVDLSGLAQSFANGVKALNPLDWTQYFIFIGVGALLLVIVLMIFPIVFQCLAKSLDQVQSDLNVLLLKKKKGGNAAPAAEMVELPRVSYT
What is the function of this protein?
The transmembrane protein (TM) acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm (By similarity).
What are the official names of this protein?
Envelope glycoprotein gp70, Env polyprotein.
What are the subcellular locations of this protein?
[Transmembrane protein]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Surface protein]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM. Both proteins are thought to be concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag (By similarity).
Protein: LSPA_BURM9
Sequence: MAKTLSKSSGGALAPWLGISLIVILFDQLTKIAVLKTFAYGAMHALTPFFNLTLIYNRGAAFGFLATAGGWQRWAFTALGIGATLVICYLLKRHGHQRLFSLSLALILGGALGNVIDRLIYGHVIDFLDFHVGAWHWPAFNLADSAITVGAVLLIYDELRRVRGAR
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ABCG1_HUMAN
Sequence: MACLMAAFSVGTAMNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSLPRRAAVNIEFRDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGDAEVNPFLWHRPSEEVKQTKRLKGLRKDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLYLGIGNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSLKAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIYGLDREDLHCDIDETCHFQKSEAILRELDVENAKLYLDFIVLGIFFISLRLIAYFVLRYKIRAER
What is the function of this protein?
Catalyzes the efflux of phospholipids such as sphingomyelin, cholesterol and its oxygenated derivatives like 7beta-hydroxycholesterol and this transport is coupled to hydrolysis of ATP (PubMed:17408620, PubMed:24576892).  The lipid efflux is ALB-dependent (PubMed:16702602).  Is an active component of the macrophage lipid export complex.  Could also be involved in intracellular lipid transport processes.  The role in cellular lipid homeostasis may not be limited to macrophages.  Prevents cell death by transporting cytotoxic 7beta-hydroxycholesterol (PubMed:17408620).
What are the official names of this protein?
ATP-binding cassette sub-family G member 1, ATP-binding cassette transporter 8, White protein homolog.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cell membrane. Note=Predominantly localized in the intracellular compartments mainly associated with the endoplasmic reticulum (ER) and Golgi membranes.
Protein: ASA1_CANGA
Sequence: MERAATHFLRLHKSGISALCSGVIDPDYGITSPVLFSGDIDGEVTIWNLITRRPIFTSKICNEQVVDIQFLEGKYLSLLCKDHKLRLYELLKLGAIVKQSDFGGGDKVDLKQIFEVPVNTLNFANYVLTYLGNNKFELVTCHTQDAHFIDIYEFETPELNSLKRFSKAIDFLPMLRDRFGDNLLPKMDGLGIIMKFYKVNEVVYCGFESGYVIAFRRYRNKPLYRKRVSGFIGKPINECASGISKLLQHENVETSSSVNDLELDNVIEIVLVDRAHYPDPVLDMAPNPKKNGIICSSTTNKLVLTSVDEQYLAGPNSAYIFKSDEYLLDKKNCLLMSTNLKIDGSAVKDMMCKNIGFVLSLGDYIITGNWSGKTYIGRIESDKAVLAAAKSRSLIEVNESPVGNIQQDKSIQKSSKHTKIGAMTGFEVKDKEPDKLMCKNKELTPGKLRRLNAFVQSKWYFIGYTDGTIGLYRAE
What is the function of this protein?
Component of the ASTRA complex involved in chromatin remodeling.
What are the official names of this protein?
ASTRA-associated protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat ASA1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LEUD_CHLAD
Sequence: MEPISTITGKVVVLPVENIDTDQIIPARFLKVTDKSGLAAGLFEAWRYLPDGTLNPDFPLNRPEAAGATILISGRNFGCGSSREHAPWALQDYGFQAVIAPSFADIFRNNALKIGLLPVMVEQSVYDELVVMYANDPSMVLTIDLAAQIVALPDGRQVHFPIDAFSKYCLLHGVDQLGFLLQQEAAIAAYEAAHPQPVQTTVRR
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: KPPR1_CUPNH
Sequence: MSERYPIIAITGSSGAGTTSVTRTFENIFCREGVKSVVIEGDSFHRYDRAEMKVKMAEAERTGNMNFSHFGAENNLFGDLESLFRSYAESGTGMRRRYLHSTEEAAPFGQQPGTFTAWEPLPADTDLLFYEGLHGGVVTDEVNVAQYPNLLIGVVPVINLEWIQKLWRDKKQRGYSTEAVTDTILRRMPDYVNYICPQFSRTHVNFQRVPCVDTSNPFISREIPAPDESMVVIRFANPKGIDFQYLLSMIHDSFMSRANTIVVPGGKMELAMQLIFTPFVLRMMERRKRAAL
What are the official names of this protein?
Phosphoribulokinase, plasmid, PRK, PRKase, Phosphopentokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoribulokinase family.
Protein: Y544_RICPR
Sequence: MCRLAKIISNAGVCSRRNAEKLIVGGKVKIDGITILSPATNVDMSNQIEVSGRLINNTQKPRLWIYYKPVGLITTHKDPLSRKTVFEQLIGLPRVISIGRLDLNSEGLLLLTNSGDLAHQFEMPASKLKRVYNVRAYGNPNILLKNNYKNLKIDGIFYNPHSIKLLRQNKSNSWFEVVLFEGKNREIRRIFEYFGLQVNKLIRIQYGALKIGNLKPGNYQEISNKILEKQLVMCF
What are the official names of this protein?
Uncharacterized RNA pseudouridine synthase RP544, RNA pseudouridylate synthase, RNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RsuA family.
Protein: MDH_CHLAB
Sequence: MVMKLTRTVSVAVTGGTGQIAYSFLFALAHGDVFGSDCGIDLRIYDLPGLERVLSGVRMELDDGAYPLLQSLRVTTSLEDAFDGIDAAFLIGAAPRGPGMERSDLLKRNGEIFSLQGSVLNTSAKRDAKIFVVGNPVNTNCWIAMSQAPRLNRRNFHSMLRLDQNRMHTMLAHRAEVPLDEVSHVVIWGNHSAKQVPDFTQALISGKPAVEVIGDRDWLENIMLPSIQNRGSAVIEARGKSSAASAARALAEAARSIFLPKDGEWFSTGVCSDYNPYGIPEDLIFGFPCRMLPSGDYEIVPGLLWDTFIKNKIQISLDEISQEKANVSLL
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: YKAD_CAEEL
Sequence: MSRLAGRVVFPGEAEPQSSSTNSRAPESSSSSQETRQQNLANRFKPSNNYRSNRNQVEDGETTNSNRGKPRGKGPIRYQGNYSDRFVGRQEEAPRAEKSERSERPQRSEKPQDQNQREQVKPQRKQTKRVENVVASEELLELEDIIDQISDLNVRNDRSAAQIKRNILGSHDLIDTMDEDDWQKVCESMIKTALEQGEPEFIADLMVALFSNKLFAAVMSDELMKYVTKYIMEDDEMPIPSLLSAILCAHWPRQLAKAFDNINPILYTIVCLIKGWIEVVREDTERYYKEEKKPKYQVAREDSFEEPTPEPSKEEEEKIIEEPEMVNRCAVGLSDLCDTAQRQLWVNWMTVTDEIYQCIKPSITHNPNITGSVKGRLLDTFLQMNQWTKNRTASVKHAVTQTVGTSN
What are the official names of this protein?
Uncharacterized protein B0303.14.
Protein: PLSY_ACTP2
Sequence: MSITVYLLIVFAYLLGSVSSAIIFCRLAGLPDPRENGSHNPGATNVLRIGGKFSALGVLLFDILKGGLPVLLAFNFKLEPSEIGLIALAACLGHIFPLFFRFRGGKGVATAFGALLSISFAASAAGLCTWLIVFLLFGYSSLSAVITALIMPFYIWWFLPEFTFPVALVCCLLVYRHHDNIQRLWRGQEQPMWARK
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DSCR6_MOUSE
Sequence: MRPEAAGVREARGRLCHCPGDDPGRLPLPRGPESSIPAPWRPWMSPPPGDAELTRTERPCESWGDQHTSGSKGAFGFQHPVRLYLPVSKRQEYLQSSGEKVLASFPVQATIHFYNDDSESGSEEEQEEEAQPNHLQCLEAEVRDSAQEERAE
What is the function of this protein?
Acts as a transcriptional corepressor.  Negative regulator of the transcriptional activity of TBX1.  Plays a role in the development of the pharyngeal apparatus and derivatives.
What are the official names of this protein?
Protein ripply3, Down syndrome critical region protein 6.
What is the protein family that this protein belongs to?
Belongs to the ripply family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TATE_ESCF3
Sequence: MGEISITKLLVVAALVVLLFGTKKLRTLGGDLGAAIKGFKKAMNDEDAGAKKDANGDLPAEKLTHKE
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatE shares overlapping functions with TatA.
What are the official names of this protein?
Probable Sec-independent protein translocase protein TatE.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family. TatE subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: NDK_ROSS1
Sequence: MERSLIILKPDAVQRGLIGPILTRIEQRGLRIVGMKLMQIDESLARRHYAIHEGKAFFDSLITYITSGPVVVLVVTGKNIIEIVRSMVGATNPVKAAPGTIRGDFALDIGRNLIHASDSPENGEMEVSLFFRPEELVEMHRSTDQWIYE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTM1_KLULA
Sequence: MEAATEWLLENTPITKSECTTIRESVVDGDTGGYGVFVNFTKLRTLKGEKDSKFELLRIPRSATISMTSIRDILAKSTSENAVTASIKGHLTAFLSDENHHAFINETNLIVIYLVLKAILSDNKTYKLTGFASFYLNEVLLKTFVPLPCNTFQEDADKWNQYYKEYLNFPQQLFIEIINRFISARFLGMNYEKLISTVYCSVISRILEIPESSGEDTDDFFVSPTLVPLLDFVNHDNDHRNAHFDIDLRTNDIVLYLELDDIDSTVEEAQVFISYAPVEELVHFEQIYGFLPKSNNVQVWCYRFDEDFLSTYHYNGINVSHFYKCMRVRPSFQILILPSEVLINDCIVEFGELLILFSQHLQDPKKISFQLSETNDSYCSILKDKCGTETTKLLDKEECLEEFFGEHDEIENYEKTLKEFKSFLSKYITFRREKISSINLLSQNSSFTAFWQKEINLLDSLKGQFESKKEVMWYEKYGNDEKIKIPTVPFPPPSWIDYENMRV
What is the function of this protein?
Methyltransferase which mediates trimethylation of cytochrome c (CYC1).
What are the official names of this protein?
Cytochrome c lysine N-methyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: CAE32_RANCI
Sequence: QQDYGTGWFDF
What is the function of this protein?
Hypotensive neuropeptide.
What are the official names of this protein?
Caerulein-3.2/3.2Y4.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: LYP4_ORYSJ
Sequence: MPPPLLLLLLLAAAAAAVAPARSKSTLESCSSSTACPALLSYTLYADLKLAELAALFSADPLAILAANSIDFAVPDPADRILPAGLPLRVPVPCACSDGIRRVTTVRYVARPGDTLASVASSVYGGLTTPDWISDSNGILGAKPDAAVDAGTTLFVPLHCACFGGVDNGLPAVYLTYVAGKGDTVAAVAQRYRTTATDLMSVNDMATPELAAGDIIVVPLPACTSSFPAFTADYGLAVANGTYAVTANRCVQCSCGPGNLDLFCVPAPLADSTCSSMQCANSSMMLGNFTLLMTSSGCSVTSCSYGGFVNGTILTTLTTALKPQCPGPHQYPPLIPPPTSSFFETYLGPSPTPMASEGGVMAGMAPTSTPAASSGPPPAGRHVVGDVLGAFALCLVGNLLW
What is the function of this protein?
Functions in innate immunity.  Functions as pattern recognition receptor (PRR), sensing bacterial peptidoglycan (PGN) and fungal chitin at the cell surface.  Involved in resistance against the bacterial pathogen Xanthomonas oryzae pv.  oryzae (Xoo) and the fungal pathogen Magnaporthe oryzae.  Binds PGN and fungal chitin in vitro (PubMed:22872757).  Involved in microbe-associated molecular patterns (MAMPs) perception and participates in the activation of defense genes against the bacterial pathogen Xanthomonas oryzae pv.  oryzicola (Xoc) or the fungal pathogen Magnaporthe oryzae (PubMed:23299421).
What are the official names of this protein?
LysM domain-containing GPI-anchored protein LYP4, LysM domain-containing protein 4, Os-LYP4.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: UBIQP_ACEPE
Sequence: IPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVQSSDTVENVKSKIQDKEGIPPDQQRLIFAGKQLEDGLTLADYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTVENVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTVENVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTVENVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTVENVKSKIQDKEGIPPDQQRIIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGAF
What is the function of this protein?
Ubiquitin exists either covalently attached to another protein, or free (unanchored).  When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains).  Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in lysosomal degradation; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B.  Linear polymer chains formed via attachment by the initiator Met lead to cell signaling.  Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed.  When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling (By similarity).
What are the official names of this protein?
Polyubiquitin.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.