PharMolix/UniProtQA huggingface dataset:
Protein: ESR1_ORYLA
Sequence: MSKRQSSVQIRQLFGPALRSRISPASSELETLSPPRLSPRDPLGDMYPEESRGSGGVAAVDFLEGTYDYAAPNPATTPLYSQSSTGYYSAPLETNGPPSEGSLQSLGSGPTSPLVFVPSSPRLSPFMHPPSHHYLETTSTPVYRSSHQGASREDQCGSREDTCSLGELGAGAGAGGFEMAKDTRFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDRNRRKSCQACRLRKCYEVGMMKGGVRKDRIRILRRDKRRTGVGDGDKVVKGQEHKTVHYDGRKRSSTGGGGGGGGGRLSVTSIPPEQVLLLLQGAEPPILCSRQKLSRPYTEVTMMTLLTSMADKELVHMIAWAKKLPGFLQLSLHDQVLLLESSWLEVLMIGLIWRSIHCPGKLIFAQDLILDRNEGDCVEGMTEIFDMLLATASRFRVLKLKPEEFVCLKAIILLNSGAFSFCTGTMEPLHNSAAVQSMLDTITDALIHYISQSGYLAQEQARRQAQLLLLLSHIRHMSNKGMEHLYSMKCKNKVPLYDLLLEMLDAHRLHHPVRAPQSLSQVDRDPPSTSSGGGGIAPGSISASRGRIESPSRGPFAPSVLQYGGSRPDCTPALQD
What is the function of this protein?
The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.
What are the official names of this protein?
Estrogen receptor, ER, ER-alpha, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATE1_MOUSE
Sequence: MASWSAPSPSLVEYFEGQTSFQCGYCKNKLGSRSYGMWAHSMTVQDYQDLIDRGWRRSGKYVYKPVMDQTCCPQYTIRCHPLQFQPSKSHKKVLKKMLKFLAKGEISKGNCEDEPMDSTVEDAVDGDFALINKLDIKCDLKTLSDLKGSIESEEKEKEKSIKKEGSKEFIHPQSIEEKLGSGEPSHPIKVHIGPKPGKGADLSKPPCRKAREMRKERQRLKRMQQASAAASEAQGQPVCLLPKAKSNQPKSLEDLIFQSLPENASHKLEVRVVRSSPPSPQFRATFQESYQVYKRYQMVVHKDPPDKPTVSQFTRFLCSSPLEAEHPADGPECGYGSFHQQYWLDGKIIAVGVLDILPYCVSSVYLYYDPDYSFLSLGVYSALREIAFTRQLHEKTSQLSYYYMGFYIHSCPKMRYKGQYRPSDLLCPETYVWVPIEQCLPSLDNSKYCRFNQDPEAEDEGRSKELDRLRVFHRRSAMPYGVYKNHQEDPSEEAGVLEYANLVGQKCSERMLLFRH
What is the function of this protein?
Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein.  This arginylation is required for degradation of the protein via the ubiquitin pathway.  Does not arginylate cysteine residues.
What are the official names of this protein?
Arginyl-tRNA--protein transferase 1, Arginyltransferase 1, R-transferase 1, Arginine-tRNA--protein transferase 1.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family.
What are the subcellular locations of this protein?
[Isoform ATE1-1]: Nucleus. Cytoplasm. SUBCELLULAR LOCATION: [Isoform ATE1-2]: Cytoplasm.
Protein: UVRB_STRPQ
Sequence: MIDKRDDKPFKLKSKYKPSGDQPQAIESLVDNIEGGEKAQILLGATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPDNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYADSAVSLRPGQEISRDTLLNQLVDIQFERNDIDFQRGCFRVRGDVVEVFPASRDEHAFRVEFFGDEIDRICEIESLTGKTIGEVDHLVLFPATHFVTNDEHMEQSIAKIQAELAEQLQLFESEGKLLEAQRLRQRTEYDIEMLREMGYTSGVENYSRHMDGRSPGEPPYTLLDFFPEDFLIMIDESHMTMGQIKGMYNGDQARKQMLVDYGFRLPSALDNRPLRREEFESHVHQIVYVSATPGEYEMSQTNTIIEQIIRPTGLLDPEIDVRPSMGQMDDLLGEINQRVARDERTFITTLTKKMAEDLTDYLKEMGVKVKYMHSDIKTLERTEIIRDLRLGVFDVLIGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNVDGHVIMYADKMTDSMQRAIDETARRREIQIAYNKAHGIVPQTIKKDIRGLISISKTSHNDISKEEMDYESMSRGERKEAINALQKQMQEAAELLDFELAAQMRDLILELKLMD
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPG_BACMK
Sequence: MTQRTKTRPVKVGNLTIGGNNELIIQSMTTTKTHDVEATVAEIKRLEEAGCQVVRVAVPDERAANAIADIKKQINIPLVADIHFDYRLALKAIEGGIDKVRINPGNIGRRHKVEAVVNAAKERGIPIRIGVNAGSLERHILEKYGYPTADGMVESALHHIKILEDLDFHDIIVSMKASDVNLAIEAYEKAARAFDYPLHLGITESGTLFAGTVKSAAGLGAILSKGIGNTLRISLSADPVEEVKVARELLKSFGLASNAATLISCPTCGRIEIDLISIANEVEEYISTLKVPIKVAVLGCAVNGPGEAREADIGIAGARGEGLLFRKGQVVRKVPEETMVEELKKEIDVIAAEMAAEREKEKQEQ
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: RL28_ONYPE
Sequence: MSKCYITGKTTLFGNRRSHAMNATKRIWKANLQNVKIVDENGKVQKVKISARALKKLKLQRA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: GLYCO_MMVR
Sequence: MSLIHLIYFPTILSLILGTEGTPALTYGNLADNQHGNEEQGDVDMYPLYECSKKGAGVSSNNWYGACRGACSMTKNTTDVHMEIYYRNDSVGWIDVLSIQTTEIWKHSHVTWYGECEHNTKYGSSNTAPVSVILERLEFLHNGMSSWPYGHSIHVHDTISSPDCSYFDDVSRSGWRLIISKRALELKSDIAGEGYIVDPDVGYVYPVADGIGKGRTWHVWKASSVPSSGCYFKSAGITNCTLLMDTFLYSCPSLNIAFSARVGKHIKSTCVGDMNISTDGVTYQTLGSTDQGSISTQLVSLWHQSQEALIQQLILTINEALGKIETSYCESTCDLTEMLISQHTEHPMVIETPVGPWLPYSIDGKVSVLPCQGGQDLVVIKPIEICASPFMLKVKSLKSLDTYWWVPTDSHVAPFTQCSNRDDEEMIIKIQRKKPLIFEFWRGAYKLDYPYNSSGIWLDNPGGHIHRSSKWFPTLDSLSYSSPINLPLISKGIRKHIQAIVSTTEITSGGNVTSWTHSISTIAEAMFDSAAIAAGRVVMWWYTLEESVKRYLTVAFGLVLTVITIWAMSKLFFRSSPTYARAPTNIEWVRS
What is the function of this protein?
Attaches the virus to host cellular receptor, inducing endocytosis of the virion.  In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane (By similarity).
What are the official names of this protein?
Glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the nucleorhabdovirus glycoprotein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein.
Protein: UBIB_SALG2
Sequence: MTPGEVRRLYFIIRTFLSYGLDELIPRMRLTLPLRLWRYSLFWMPNRHKDKLLGERLRLALQELGPVWIKFGQMLSTRRDLFPPQIADQLALLQDKVAPFDGRLAKAQIEEAMGGLPVDAWFDDFDIQPLASASIAQVHTARLKSNGKEVVIKVIRPDILPVIQADLKLIYRLARWVPRLLPDGRRLRPTEVVREYEKTLIDELNLLRESANAIQLRRNFENSPMLYIPEVYSDYCSQNMMVMERIYGIPVSDVAALEKNGTNMKLLAERGVKVFFTQVFRDSFFHADMHPGNIFVSHEHPENPQYIGIDCGIVGSLNKEDKRYLAENFIAFFNRDYRKVAELHVDSGWVPPDTNVEDFEFAIRTVCEPIFEKPLAEISFGHVLLNLFNTARRFNMEVQPQLVLLQKTLLYVEGVGRQLYPQLDLWKTAKPFLESWIKDQVGIPALTRALKEKAPFWVEKMPEIPELVYDSLRQGKYLQHSVDKIARELQVNHVRQSQSRYLLGIGATLLLSGSFLLVNRPEWGLMPSWLMVGGVVVWLVGWRKTR
What is the function of this protein?
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
What are the official names of this protein?
Probable protein kinase UbiB, Ubiquinone biosynthesis protein UbiB.
What is the protein family that this protein belongs to?
Belongs to the ABC1 family. UbiB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NDK_VIBCH
Sequence: MALERTFSIIKPDAVKRNLIGEIYHRIEKAGLQIIAAKMVHLSEEQASGFYAEHEGKPFFEPLKEFMTSGPIMVQVLEGENAIARYRELMGKTNPEEAACGTLRADYALSMRYNSVHGSDSPASAAREIEFFFPESEICPRP
What is the function of this protein?
(Microbial infection) Catalyzes the phosphorylation of dZDP to dZTP, when the bacterium is infected by a phage that produces the substrate for the synthesis of dZTP (2- amino-2'-deoxyadenosine 5'-triphosphate), which is then used by the phage as a DNA polymerase substrate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_RHOPS
Sequence: MASLKDMRVRIASTKATQKITKAMQMVAASKLRRAQMAAEAARPYAEKMDAVISNIAGAAAGSPGAPVLLAGTGKDQVHLLLVCTGERGLSGAFNSSIVRLARERAYALMNQGKTVKFFCVGRKGYEQLRRTFDKQIIENIELRSVRQLGFVNAEDIAQKVIARFNNGEFDVCTLFYSRFKSVISQIPTAQQLIPLVVEAPAAGSVATSYEYEPEEDEILSTLLPRNLAVQIFRALLENNASFYGAQMSAMDNATRNAGDMIRKQTLIYNRTRQAMITKELIEIISGAEAI
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MRT4_CANGA
Sequence: MPRSKRSKLVTLAQTDKKGRENKERIFDEVREALDTYKYVFVLQLDDVRTPVLQEIREAWVGSKLLMGKRKVLEKALGTTREQEYKENLSKLTKYCSGVIGLLFTNETLDTVKEYFEAYSRLDYSRPNSRAPITFEVPEGIVYSRGGQIPIEEDVPMAHSLEPTLRNKYEMPTKIKAGKITLEAPYLVCKEGQKLDVRQALILKQFGVALAQFKVIISAYYDNESSTVSELNINKKQDA
What is the function of this protein?
Component of the ribosome assembly machinery.  Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
What are the official names of this protein?
Ribosome assembly factor mrt4, mRNA turnover protein 4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm.
Protein: YHAL_ECOLI
Sequence: MSKKLAKKRQPVKPVVAKEPARTAKNFGYEEMLSELEAIVADAETRLAEDEATA
What are the official names of this protein?
Uncharacterized protein YhaL.
Protein: MSCL_ENT38
Sequence: MSIVKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDAQGDIPAVVMHYGVFIQNVFDFVIVAFAIFMAIKLINRLNRKKEEPAAVPPAPSKEEVLLTQIRDLLKEQNNRI
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATP68_MOUSE
Sequence: MFQTLIQKVWVPMKPYYTQVYQEIWVGVGLMSLIVYKIRSADKRSKALKGPAPAHGHH
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Minor subunit required to maintain the ATP synthase population in the mitochondria.
What are the official names of this protein?
ATP synthase subunit ATP5MPL, mitochondrial, 6.8 kDa mitochondrial proteolipid protein, MLQ, ATP synthase membrane subunit 6.8PL.
What is the protein family that this protein belongs to?
Belongs to the small mitochondrial proteolipid family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: RL18_BACCR
Sequence: MITKADKNATRKKRHARVRAKLTGTAERPRLNVFRSNQHIYAQVIDDVNGVTLVSASTLDKDLALNGTSNIEAATKVGESVAKRAVEKGVKEVVFDRGGYLYHGRVKALAEAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: GSA_THEM4
Sequence: MFEKAKEFMPGGVNSPVRAFKSVELDPIFVKSAKGSKIKDINNNEYIDYIQSWGALILGHSHEVVINAINEQSQKGTSYGLCHPLEVEMAQILVENIPSIEMVRMVNSGTEAVMSAIRLARAYTKRDFIVKFEGCYHGHSDSLLVKAGSGALTFGTPNSEGVTKEFVSKTIVAKYNDVQNINEIFENFGDKIACVIVEPIAGNMGVVPPKPNFLLTLRKLTKKYNSILIFDEVITGFRVSQNGAQGLFNVIPDLTTLGKVIGGGLPVGAFGGKKEIMQLISPQGPVYQAGTLSGNPLTLAAGVSTLKFILNNKNFYKKLDELAKTLEEGLLYALKDFNIKVNRVGSMISFFFNGSSVDTYEKVISSDVNMYKKLFKYFLSYGILLPPSPFESLFISYAHTNEDIQQTIDIAMKFSKNLKEGKV
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_HALSA
Sequence: MAETIEVLVAGGQADPGPPLGPELGPTPVDVQAVVQEINDQTEAFDGTEVPVTIEYEDDGSFSIEVGVPPTAALVKDEAGFDTGSGEPQENFVADLSIEQLKTIAEQKKPDLLAYDARNAAKEVAGTCASLGVTIEGEDARTFNERVDDGDYDDVLGDELAAA
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RPPH_SHEB8
Sequence: MIDSDGFRANVGIIICNRYGQVMWARRFGQHSWQFPQGGVDDGETAEEAMYRELYEEVGLRPEHVHILTSTRSWLRYRLPKRLVRQDSKPVCIGQKQKWFLLQLKSQDSAINLSSSGHPEFDDWRWVSYWYPVRQVVSFKRDVYRKVMKEFAVTALSFQTLEIPRKRGRQKTTG
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: MYZAP_XENTR
Sequence: MMRYGSAATVTTSETASSQKPGGVCRLRLTLPAEASLRPKQEEINRDTSVNADIRSTNERRKKRNGYVLSEKNTAEPPTLHLYTIPKNNTPSAVASSGVVYGVVQRAENNHQNEVVVYEWSTNQLKEEMNYIKDVRGTLEKIREKMFGEYDEMKQKVKQLTQEIKVSSVQKEFLESHSQAQSTALDTFGTINSSLNAASIEMQKTLVDMTLENTNIKDEMKNIKHSYEESLVRLKEKQQLLDSAQNENQLLKVKIESSQEANAEVMREMTRKLYSQYEEKLRQEELKYTAEKDMLVDQTRQYLKAIEDASEKVRLAENKIEERDAKIAELDKLVHRMEQEREHLQDQLIRHEERIQDLDNRMQMQSPDRNQRLEEVATSLRERIKHLDDMVHCQQKKVKHMIEEIELLKKKVHYKDLLIQQLLERIAFLEGENTELQDKVDYLMANKPKTDKETKDIGTSCNLSESQRILTVCVTENEARSIFSI
What are the official names of this protein?
Myocardial zonula adherens protein.
What is the protein family that this protein belongs to?
Belongs to the MYZAP family.
Protein: RL22_VIBCH
Sequence: MEAIAKHNFARISPQKARLVADQIRGKSVDQALELLTFSNKKAAELVKKVLESAIANAEHNEGADIDDLRVAKIFVDEGPVMKRIMPRAKGRADRILKRSSHITVVVADR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RL3_STUS1
Sequence: MTIGVVGRKCGMTRVFTEDGVSIPVTVIEIEPNRVTQFKNEESDGYRAVQVTVGERRASRVTKAQAGHFAKANVAAGRGVWEFRLEGEEFQVGDQINAEIFQAGQLVDVTGQSKGKGFAGTIKRWNFRGQDNTHGNSVSHRVPGSIGQCQTPGRVFKGKKMSGHMGAERVTVQSLEIVRVDAERNLLLVKGAVPGATGGDVFVRPAVKARG
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: RSXD_ECODH
Sequence: MVFRIASSPYTHNQRQTSRIMLLVLLAAVPGIAAQLWFFGWGTLVQILLASVSALLAEALVLKLRKQSVAATLKDNSALLTGLLLAVSIPPLAPWWMVVLGTVFAVIIAKQLYGGLGQNPFNPAMIGYVVLLISFPVQMTSWLPPHEIAVNIPGFIDAIQVIFSGHTASGGDMNTLRLGIDGISQATPLDTFKTSVRAGHSVEQIMQYPIYSGILAGAGWQWVNLAWLAGGVWLLWQKAIRWHIPLSFLVTLALCAMLGWLFSPETLAAPQIHLLSGATMLGAFFILTDPVTASTTNRGRLIFGALAGLLVWLIRSFGGYPDGVAFAVLLANITVPLIDYYTRPRVYGHRKG
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit D, Rsx electron transport complex subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CCD91_MOUSE
Sequence: MDDDDFGGFEAAETFDGEQGGNQAVSPAVPWATFPAVSGVRLSPASPELILDHDHSSPSTGHLPPDAVISSADDTHADSSLMSQTISKAQIQQSAHTHLNIPLFPLGLTDEPSHGALALEDEPEGPGVHVSNSQLRQKISSLETKLKASEEEKQRIKKDVESLMEKHSVLEKGFLKEKEQDAVSFQARYRELQEKHKQELEDMRKAGHEALSIIVDEYKALLQSSVKQQLDAIEKQYVSAIEKQAHRCEELLHAQHQRLLDVLDTEKELLREKIQEALTQQSQEQKESLEKCLQEEMQRNKETLESAVKLEKEAMKDVITKAVGEERENLEKVHAEERELWKTEHARDQERVAEAIQAAVQEQQRMSQEAVKAAIVEEQRRSEKAMEEAVKRTRDELVEYVREQRRLDQVTRQRSLSSLELFLSCAQKQLSALIATEPVDIE
What is the function of this protein?
Involved in the regulation of membrane traffic through the trans-Golgi network (TGN).  Functions in close cooperation with the GGAs in the sorting of hydrolases to lysosomes.
What are the official names of this protein?
Coiled-coil domain-containing protein 91, GGA-binding partner.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Golgi apparatus, trans-Golgi network. Note=Colocalizes with GGA1, GGA2 and GGA3.
Protein: RS213_BURPS
Sequence: MTIIRVKENEPFEVAMRRFKRTIEKNGLLTELRAREFYEKPTAERKRKKAAAVKRHYKRIRSQMLPKKLY
What are the official names of this protein?
30S ribosomal protein S21 3.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: PAGP_PECPW
Sequence: MHLKRALITLSLITLPIIPFSSYAVESINNTGSMESPASVAADSTSNKQDESWWQRSKHNLSATWNTSQSHDIYIPAITWHNRWTYDKEKTDKYNERPWGAGYGVSRLDQDGDWHGLYIMAFKDSFNKWEPIGGYGYEKRWRPTHDQDFQLGLGFTAGFTMRDNWNYIPIPVLLPLASISYSKLSFQATYIPGTYNNGNVFFAWFRWQI
What is the function of this protein?
Transfers a fatty acid residue from the sn-1 position of a phospholipid to the N-linked hydroxyfatty acid chain on the proximal unit of lipid A or its precursors.
What are the official names of this protein?
Lipid A acyltransferase PagP, Lipid A acylation protein.
What is the protein family that this protein belongs to?
Belongs to the lipid A palmitoyltransferase family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: TTCA1_FRAT1
Sequence: MTNNTDKQTLKKLERQILRKTAQAINQYNMIEDGDKIMVCLSGGKDSYCLLEMLLLLQKKAPISFEIIAVNLDQKQPGFPEEVLPNYLKNKGVEFHIIERDTYSIVKRVIPEGKTTCGLCSRMRRGILYDFAEENNVTKVALGHHRDDIIETFFLNLFYNGSIKAMPAKLLSDDKRNIVIRPLAFVSEKETLEYSQLKEFPIIPCNLCGSQDNLQRVFIKDMLNRWEQNNPERKNVIFKALSNISPSQMLDKELFDFINISKDDIQR
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase 1, Two-thiocytidine biosynthesis protein A 1, tRNA 2-thiocytidine biosynthesis protein TtcA 1.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LST2_DROWI
Sequence: MCDDGAVCAATAAANADDKSLLARFYHADRSLTAVASELDSFDGRAEPDRCSRLVSRLRQNQDKVLAITNLIMEELLGEDRDPRAFRAKFPEEVLQENLAGQLWFGAECLAAGSSILNRETESKEMRPLAQAVTKSLGNVRVLLRDQCLRNNVPNSKTLHLDFNDCTTEQLYESLKIFDRLFAEFELSYVSAMVQVKSRHEYEMQQWIGVLFSETLQRALKMGLLDQEMVDAFDPGLMFSIPRLAIVAGLVVYNKGPLNMDMPGDQLSEMFRPFRTILIKIRDLLRNLNQQELYQLEKLLCTNEDINTKAPLGSSSIEAPSQQDYSTANTHRTLERLTVDQRNNNNNINNNSSSSSNSNSGAPSVQEDANHRSPSMLSLSTASPTPSHSIGSTFSAATSSTNPPVNWSDGDDADDDDDGDDDDEDDDDDVDDDLVGNDDSDDDDDDTTDEHLLDDIVAADCASGYLIPNTNLGNLLQPQQVTLTDNFVASDDDDGYGQVAAGAGNDEEPSTSAATRHMQRLHLPSSDSYGDADGSHNNTTTIKSPDSDGQQQHQQHTSSRQRHSHHHHRHHHHHHRHSSHSSHSHHHQHQQHHSQPHPHRTTRSGRKRCSLESPTDVDVTVVQPEPEPELVSASADNSTASSLSDDISLAMRNTTARLKFKSTENLLHRLFVCIAGVADQLQTNFASDLRQILRSVFLMNVSSSQEEIDDIPEKTKESELFEFRASENDVIQESAGSNQSIYSAEEVNPELDNVFSASGARHSAGASMQRNHTTIDNNNSTSSSPPDATITTTTTTTTTRSHVTRSRSLGDQEVVASAAAAAAAAVNEEREMQRQRNNSVGSNTPSSASSSATSSSSEQNSPVSMRSGTGRRRHQSNNETQMPTTATTTTTTGTGTLAPPAWIPDGKAPRCMSCQTPFTAFRRRHHCRNCGGVFCGVCSNASAPLPKYGLTKAVRVCRDCYAREIRSSGGGGGGVVQMQRQQAANRPQTASAS
What is the function of this protein?
Negative regulator of epidermal growth factor receptor (EGFR) signaling.
What are the official names of this protein?
Lateral signaling target protein 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the lst-2 family.
Protein: PFKA_STRZP
Sequence: MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGMVAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGGDGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSHRRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNIIVLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLLKEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSLS
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSB_FRAAA
Sequence: MADPMGGAGRLPAVFMTPGTSSFTDFLSQSAPHLLPGARGGLPGPVTEVAHGTTIVAVTFPGGVIMAGDRRATQGHMIAQRDVEKVHHADDFSCVGYAGTAGVGAELIRLFQVELEHYEKIEGATLSLDAKANRLAAMVKGNLPMALQGLAVVPLFAGYDPDLDKGRIFSYDIAAAKSEERTYESIGSGSVFAKGSLKKRFRVDLTQDDAVRIAVEALYDAADDDSATGGPDTIRKLYPIVASVTSDGYRRYGDDEVEPVVTAIIADRSTSAGG
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta, 20S proteasome beta subunit, Proteasome core protein PrcB.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_SALEP
Sequence: MAEITASLVKELRERTGAGMMDCKKALTEANGDIELAIENMRKSGAIKAAKKAGNVAADGVIKTKIDGNVAFILEVNCQTDFVAKDAGFQAFADKVLDAAVAGKITDVEVLKAQFEEERVALVAKIGENINIRRVASLEGDVLGSYQHGARIGVLVAAKGADEELVKQLAMHVAASKPEFVKPEDVSADVVEKEYQVQLDIAMQSGKPKEIAEKMVEGRMKKFTGEVSLTGQPFVMEPSKSVGQLLKEHNADVTGFIRFEVGEGIEKVETDFAAEVAAMSKQS
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.