PharMolix/UniProtQA huggingface dataset:
Protein: MRAY_VIBCM
Sequence: MIIWLAELLQPYFSFFRLFEYLSFRAIVSILTALGISLWMGPRMIKRLQMLQIGQVVRNEGPESHFSKRGTPTMGGVMILAAITITVLLWADLTNPYVWAVLAVLLGYGAVGFVDDYRKVVRKNTDGLIARWKYFWQSAIALVVAFALYAHGQDTAATQLVVPFFKDVMPQLGLMYIVLTYFVIVGTSNAVNLTDGLDGLAIMPTVLVAAGFAAIAWATGNVNFANYLHIPYIPHSSELVVVCTAMVGAGLGFLWFNTYPAQVFMGDVGALALGGALGTIAVLVRQEFVLVIMGGVFVMETLSVILQVGSYKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISIVLVLIGLATLKVR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GH34_ARATH
Sequence: MAVDSLLQSGMASPTTSETEVKALKFIEEITRNPDSVQEKVLGEILSRNSNTEYLKRFDLNGAVDRKSFKSKVPVVIYEDLKTDIQRISNGDRSPILSSHPITEFLTSSGTSAGERKLMPTIEEDINRRQLLGNLLMPVMNLYVPGLDKGKGLYFLFVKSESTTSGGLPARPALTSYYKSDYFRTSDSDSVYTSPKEAILCCDSSQSMYTQMLCGLLMRHEVNRLGAVFPSGLLRAISFLQNNWKELSQDISTGTLSSKIFDHAIKTRMSNILNKPDQELAEFLIGVCSQENWEGIITKIWPNTKYLDVIVTGAMAEYIPMLEYYSGGLPMASMIYASSESYFGINLNPMCKPSEVSYTIFPNMAYFEFLPHNHDGDGGVEATSLVELADVEVGKEYELVITTYAGLYRYRVGDILRVTGFHNSAPQFKFIRRENVLLSIESDKTDEADLQKAVENASRLLAEQGTRVIEYTSYADTKTIPGHYVIYWELLSRDQSNALPSDEVMAKCCLEMEESLNAVYRQSRVSDKSIGPLEIRVVQNGTFEELMDFSISRGSSINQYKVPRCVSLTPIMKLLDSRVVSAHFSPSLPHWSPERRH
What is the function of this protein?
Catalyzes the synthesis of indole-3-acetic acid (IAA)-amino acid conjugates, providing a mechanism for the plant to cope with the presence of excess auxin.  Strongly reactive with Glu, Gln, Trp, Asp, Ala, Leu, Phe, Gly, Tyr, Met, Ile and Val.  Little or no product formation with His, Ser, Thr, Arg, Lys, or Cys.  Also active on pyruvic and butyric acid analogs of IAA, PAA and the synthetic auxin naphthaleneacetic acid (NAA).  The two chlorinated synthetic auxin herbicides 2,4-D and 3,6-dichloro-o-anisic acid (dicamba) cannot be used as substrates.
What are the official names of this protein?
Indole-3-acetic acid-amido synthetase GH3.4, Auxin-responsive GH3-like protein 4, AtGH3-4, CF4-like protein.
What is the protein family that this protein belongs to?
Belongs to the IAA-amido conjugating enzyme family.
Protein: HPF_CUPNH
Sequence: MNFKISGHHLDITPPLREYVETKLERIVRHFDQVIGVSVLLSVDNHKEKDRRQYAEINLHLKGKDIFVEAHHEDLYAAIDALVDKLDRQVIRYKDRVQGHDREAVKYQMAAAQMQQ
What is the function of this protein?
During stationary phase, promotes and stabilizes dimerization of 70S ribosomes by the ribosome modulation factor (RMF), leading to the formation of inactive 100S ribosomes.
What are the official names of this protein?
Ribosome hibernation promoting factor, HPF, Hibernation factor HPF.
What is the protein family that this protein belongs to?
Belongs to the HPF/YfiA ribosome-associated protein family. Short HPF subfamily.
Protein: BIC1B_XENLA
Sequence: MAAQCGGYMNQSDPGSNSERSADSPLPGSEDDSPGSAAPHDPEWREERFRVDRKKLETMLQAAAEGKGKSGEDFFQKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKENVKEAKERIMSVLDTKSNRVTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSNRNNQAEKSNQVSIAGQPAGVESARVRIRELLPLVLMFELPIAGILQPIPDPNSPTIQQISQTYNITVSFKQRSRVYGATVIVRGSQNNTSAVKEGTAMLLEHLAGSLASAIPVSTQLDIAAQHHLFMMGRNGCNIKHIMQRTGAQIHFPDPNNPLKKSTVYLQGTIESVCLARQYLMGCLPLVLMFDMKEEIEVEPQCITQLMEQLDVFISIKPKPKQPSKSVIVKSVERNALNMYEARKCLLGLDSSGVTITNQSTISCPIPMNCHGLDILAAGLGLSGLGLLGPNTLSVNSTTAQNSLLNALNSSVSPLHSPSSAAPSPTLWATSLANTSNATGFPAIPHLMIPSAAQATLTNFLLSGVPNYGQNTPSPPPGLTPVDVHMNGLHSECKKVTSVLNGHVKPTNMKYGTISSSSLGDKVLNTNLAEASRQSNNHSSAEEVNSKTDSEGCNDAFVEVGMPRSPSHSANTKDLKQMLNSTKAPCPTRQTVKLLHGTKNSHLHTAERLLSDSEMSPTEGPMTDKKAPGSERAAERAAAQHNCEMARFTSQSAYGNMQAYDYEQKKLLATKAMLKKPVVTEVRTPTNTWSGLGFSKSMPAETIKELRRANHVPYKPTMSTTYENSPMSLSRSNSREQLGNGSDSDNWRERNGIDSSHNDYSSSIGSPKRKQNKSAEHYLSSSNYMDCISSLTGSNGCNLNSSFKGSDLPELFSKLGLGKYTDIFQQQEIDLQTFLTLTDQDLKELGITTFGARRKMLLAISELNKNRRKLFEPTNIRSSFLEGGASGRLPRQYHTDIASVSGRW
What is the function of this protein?
Putative RNA-binding protein.  May be involved in regulating gene expression during embryonic development.  Seems to be involved in endoderm formation.  Ectopic expression results in endoderm formation in the absence of mesoderm induction (By similarity).
What are the official names of this protein?
Protein bicaudal C homolog 1-B, Bic-C-B.
What is the protein family that this protein belongs to?
Belongs to the BicC family.
Protein: SMIM6_HUMAN
Sequence: MDQLVFKETIWNDAFWQNPWDQGGLAVIILFITAVLLLILFAIVFGLLTSTENTQCEAGEEE
What are the official names of this protein?
Small integral membrane protein 6.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: YBEY_PHYAS
Sequence: MKIQIHNHTSFKIDSYQQLLIQLFSQIKENNQMHLVFVTKEKIKQLNTFFRKKNFVTDVLSFPNEFSFNPNLKDDSLGDVFICFEQAQLQAQKLLHSLEREIAFLVVHGFLHLKGYQHNNEEELEKMIHLQEKILKKINLERKK
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EXO70_KLULA
Sequence: MSSIDINEADVIVLSEGLKKLDSLYSEMSQSLKKISSTTSTASQLFTPILKKNQQLNILQYNIESSLNSVASVKDLANDASKHEIILEQSIAKVGLKPYINAIHKIDDILEDLNERTHSNDTSEFAGMVTHLKELIFDGERNLQIYFNKLLNSIQPFDPQINMNKKIPFPYYDDEYLGQMSLILDYFENSTQNAQIVDLFIKQRVRLISQSLAFLEPFTKQISSGPNVPYQKGSSGVNSYTEAMLGFIANENSLIQDLYSKETSRQPVIYAKLCSPIIQNYLKIIRHNRQLLKDNRENIGLFSFELSDKVNDVLRSLRGKDIAEADYLNSELIEIQRISHSLFQELFAYINTKTRSMSQLPSDNGVPEPTVDIMSKIRKFSEYKSGCLSTIQAMSRSQWLPKDPKISWTITKNQLEDLSSANLLSSFFGDAIDYLLFGLERRAQETLNPQHEIHLLSNKRFPNIQRIGFFLLNNLSLIDQIVQRSEINSILGSAGLARLESLRKKYINYYVSDWRDLTSILLDQIFVDSSGKVSSKEKDQIKEKFKKFHDGFEDLVSRSKSYRISDPALKKILRQEILSLVLPMYERFYNRYKDSFKHPRKHIKYTPSELMNVLNTIIK
What is the function of this protein?
Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis.  Also plays a role in the assembly of the exocyst (By similarity).
What are the official names of this protein?
Exocyst complex protein EXO70.
What is the protein family that this protein belongs to?
Belongs to the EXO70 family.
What are the subcellular locations of this protein?
Bud. Bud neck.
Protein: RL25_YERPB
Sequence: MTTINVEVRNDQGKGASRRLRAANKFPAIVYGGSEAAISIALDHDTTKNLELKPGFYDSVLTLVIDGKETKVKVQAVQRHAFKPKLTHIDFVRV
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: ROP1B_HUMAN
Sequence: MAQTDKPTCIPPELPKMLKEFAKAAIRAQPQDLIQWGADYFEALSRGETPPVRERSERVALCNWAELTPELLKILHSQVAGRLIIRAEELAQMWKVVNLPTDLFNSVMNVGRFTEEIEWLKFLALACSALGVTITKTLKIVCEVLSCDHNGGLPRIPFSTFQFLYTYIAEVDGEICASHVSRMLNYIEQEVIGPDGLITVNDFTQNPRVWLE
What is the function of this protein?
Important for male fertility.  With ROPN1L, involved in fibrous sheath integrity and sperm motility, plays a role in PKA-dependent signaling processes required for spermatozoa capacitation.
What are the official names of this protein?
Ropporin-1B, Rhophilin-associated protein 1B.
What is the protein family that this protein belongs to?
Belongs to the ropporin family.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum. Note=In the sperm tail, found in the principal piece and in the cytoplasmic droplet located at the distal end of the midpiece. Inner surface of the fibrous sheath.
Protein: GUC2G_MOUSE
Sequence: MASRTRSESPLEPRLYAGAGSRADHPSLVLMLSVVMLVTCLEAAKLTVGFHAPWNISHPFSVQRLGAGLQTVVDKLNSEPVGLGNVSWEFTYTNSTCSAKESLAVFIDQVQKEHISALFGPACPEAAEVIGLLASEWNIPLFDFVGQMAALKDHFWCDTCVTLVPPKQEISAVLRESLRYLGWEHIGVFGGSSADSSWEQVDEMWGAVEDGLQFHFNITASMRYNSSSSDLLQEGLRNMSYVARVIILICSSEDARRILQAAVDLGLDTGEFVFILLQQLEDSFWKEVLTKDKVIRFPKVYESVFLIAPSAYGGGIGDDGFRKQVSQELRRPPFQSSITSEDQVSPYSAYLHDALLLYAQTVEEMRKAEKDFRDGRQLISTLRAGQVTLQGITGPVLLDSQGKRHVDYSVYALQESGNRSLFLPFLHYDSFQKVIRPWRNDSNTSWPHGSLPEYKPGCGFHNDLCKTKPPTVAGMTVTVTAVIPTVTFLVLASAAAITGLMLWRLRGKVQSHPGDTWWQIRYDSITLLPQHKLSHRGTPVSRRNVSDTSTVKASADCGSLVKRHQDEELFFAPVGLYQGNQVALCYIGDEAEAWVKKPTVRREVCLMCELKHENIVPFFGVCTEPPNICIVTQYCKKGSLQDVMRNSDHEIDWIFKLSFAYDIVNGLLFLHGSPLRSHGNLKPSNCLVDSHMQLKLSGFGLWEFKHGSTWRSYNQEATDHSELYWTAPELLRLRESPCSGTPQGDVYSFAILLRDLIHQQAHGPFEDLEAAPEEIISRIKDPRAPVPLRPSLLEDKGDGRIVALVRECWDESPELRPIFPSIKKTLREASPRGHVSILDSMMGKLETYANHLEEVVEERTRELVAEKRKVEKLLSTMLPSFVGEQLIAGKSVEPEHFESVTIFFSDIVGFTKLCSLSSPLQVVKLLNDLYSLFDHTIQSHDVYKVETIGDAYMVASGLPIRNGAQHADEIATMALHLLSVTTHFQIGHMPEERLKLRIGLHTGPVVAGVVGITMPRYCLFGDTVNMASRMESSSLPLRIHVSQSTAGALLAAGGYHLQKRGTISVKGKGEQTTFWLKGKDGFPVPLPEFTEEEAKVSEIL
What are the official names of this protein?
Guanylate cyclase 2G, Guanylyl cyclase receptor G, mGC-G.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: LPXK_SHIFL
Sequence: MIEKIWSGESPLWRLLLPLSWLYGLVSGAIRLCYKLKLKRAWRAPVPVVVVGNLTAGGNGKTPVVVWLVEQLQQRGIRVGVVSRGYGGKAESYPLLLSADTTTAQAGDEPVLIYQRTDAPVAVSPVRSDAVKAILAQHPDVQIIVTDDGLQHYRLARDVEIVVIDGVRRFGNGWWLPAGPMRERAGRLKSVDAVIVNGGVPRSGEIPMHLLPGQAVNLRTGTRCDVAQLEHVVAMAGIGHPPRFFATLKMCGVQPEKCVPLADHQSLNHADVSALVSAGQTLVMTEKDAVKCRAFAEENWWYLPVDAQLSGDEPAKLLTQLTSLASGN
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: MURI_ACTPJ
Sequence: MKPTILLYDSGMGGLTIYDAIRQTLPNAHYLYCFDNAYFPYSERSENVLIEQAVKIVQKIAEKYPLDMVVVACNTASTVVLPALREKFAFPIVGTVPAIKPAAAISQTKTIGLLATKGTVERPYVAELIEKYAKDCIVEKIGTTTLVELVEEKIRTGQVDQERLIEVIAEWQTHPTLDTVILGCTHFPLVKQELQQLLPNVKYFIDPGNGIANRVSALLSESVPEEPEQNKENIAFCTKIDEEFFKREVIMQQWGFKRLELLNFL
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: TRMD_DESPS
Sequence: MLFNILTIFPNLLSSPLEEGILKRAQNSGSIDVNIVDIRQYASDKHSTTDARPYGGGEGMVMKAEPLSLAVQDIKKKDAGRVIFLTPQGRKYTQRVAEELAQESSITLVCGRYEGVDERFCEKYIDDEISLGDFILTGGELAALMVVDSVSRILPGVLGCDASVTNDTFSRHLLKHPQYTRPRIFEGLEVPDVLLSGDHQAIEDYRFIASVERTFHKRPGLLKKEIFNKREKKLLKQHNLYSKIVALQDID
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RET7_HUMAN
Sequence: MPADLSGTWTLLSSDNFEGYMLALGIDFATRKIAKLLKPQKVIEQNGDSFTIHTNSSLRNYFVKFKVGEEFDEDNRGLDNRKCKSLVIWDNDRLTCIQKGEKKNRGWTHWIEGDKLHLEMFCEGQVCKQTFQRA
What is the function of this protein?
Intracellular transport of retinol.
What are the official names of this protein?
Retinoid-binding protein 7, Cellular retinoic acid-binding protein 4, CRABP4, CRBP4, Cellular retinoic acid-binding protein IV, CRABP-IV.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MVP_CMVKI
Sequence: MAFQGTSRTLTQQSSAASSGDLQKILFSPDAIKKMATECDLGRHHWMRADNAISVRPLVPQVTSNNLLSFFKSGYDAGELRSKGYMSVPQVLCAVTRTVSTDAEGSLKIYLADLGDKELSPIDGQCVTLHNHELPALISFQPTYDCPMELVGNRHRCFAVVVERHGYIGYGGTTASVCSNWQAQFSSKNNNYTHAAAGKTLVLPYNRLAEHSKPSAVARLLKSQLNNVSSSRYLLPNVALNQNAAGHESEILNESPPFAIGSPSASRNNSFRSQVVNGL
What is the function of this protein?
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier.  Acts by forming a tubular structure at the host plasmodesmata, enlarging it enough to allow free passage of virion capsids (By similarity).
What are the official names of this protein?
Movement protein, MP, Protein 3A.
What is the protein family that this protein belongs to?
Belongs to the cucumovirus movement protein family.
What are the subcellular locations of this protein?
Host cell junction, host plasmodesma. Note=Assembles into long tubular structures at the surface of the infected protoplast.
Protein: TRPD2_RALSO
Sequence: MFDLKATIGRLAQGQTLGRQDAWMLFEQMAFGHASHAQLGALLMALRVRGETVEEIVGAALAMRARMVPVKAPADAVDIVGTGGDNAGTYNISTCAAFIVAGAGVPVAKHGNRALSSKSGAADVLSALGVNLDQTPADIERCIAEAGIGFMFAPTHHPALKQLMPVRVDLATRTIFNLLGPLLNPAGVRHHLIGVYSRAWVEPLAHALGDLGSERALVVHGSDGLDEITTVGPTFVSMLARGRVRSFEITPEMVGLVRANPAELKGADGKWNAVALRRVLEGQPGAYRDIALFNAAGGLIAAGVVENWPDAMALARASVDGGAALATLNRLVEASQPEGHVQPY
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: TM102_MOUSE
Sequence: MASTVWGGAPWWGPPPPAPARPLTDIDFCSGAQLQELTQLIQELRVQESWSEGPKPGADLLRAKDFVFALLGLVHRQDPRFPPQAELLLLRGGIREGSLDLGHAPLGPYSRGPHYDAGFTLLVPVFSLDGTGPELLLDLESCSAWLRLPELMRGILVREAWQDCLGPPVPEESDMTHQTHSKESPTDRENSVDPSHDYVPEPEPHMSLQKSSSDLSESQSSYKDITNPETPEPLETLSSDALDADESQVPKPSEAPKAWPTLCPTQVTSWFFVKLAEVAESLIPVPGAPRLVHAARHAGVTTVLLATPEPPRHLLLFDLIPVVTVTGWPDTARSHSWAGPLVSESASFYLVPGSLPEQPSTSGWQLCFARQELALKERIPTPLLQAHAAAQALLRPLVAGTRAAAPYLLRTLLYWACERLPALYLARPENAGACCLGLLDELSRVLEAGALPHYFLSGRKLRVGDGSAALRGALAQLRGDPAQALREAVEEAKVARKGGGLAGVGGGTH
What is the function of this protein?
Selectively involved in CSF2 deprivation-induced apoptosis via a mitochondria-dependent pathway.
What are the official names of this protein?
Transmembrane protein 102.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=Also located in intracellular compartments.
Protein: PTAD_PESFW
Sequence: MAEMSKNPASTLKPSRYLCLTICGYRKPGMSEEDYRYHMTQVSAPMTKDLMAKYGVKRWTMNYMIRRWPSCPTLTASAKLCLRTLEDYKRMKQDPWYKEHLIGDHEKFADTKRSKMTIGWIEEWISDGKPVDGLEFKS
What is the function of this protein?
Probable decarboxylase; part of the gene cluster that mediates the biosynthesis of pestheic acid, a diphenyl ether which is a biosynthetic precursor of the unique chloropupukeananes (PubMed:24302702).  The biosynthesis initiates from condensation of acetate and malonate units catalyzed by the non-reducing PKS ptaA (PubMed:24302702).  As the ptaA protein is TE/CLC domain-deficient, hydrolysis and Claisen cyclization of the polyketide could be catalyzed by ptaB containing a beta-lactamase domain (PubMed:24302702).  The ptaB protein might hydrolyze the thioester bond between the ACP of ptaA and the intermediate to release atrochrysone carboxylic acid, which is spontaneously dehydrated to form endocrocin anthrone (PubMed:24302702).  Endocrocin anthrone is then converted to endocrocin, catalyzed by the anthrone oxygenase ptaC (PubMed:24302702).  Spontaneous decarboxylation of endocrocin occurs to generate emodin (PubMed:24302702).  An O-methyltransferase (ptaH or ptaI) could methylate emodin to form physcion (PubMed:24302702).  PtaJ could then catalyze the oxidative cleavage of physcion, and rotation of the intermediate could then afford desmethylisosulochrin (PubMed:24302702).  PtaF, a putative NADH-dependent oxidoreductase, might also participate in the oxidative cleavage step (PubMed:24302702).  Desmethylisosulochrin is then transformed by another O-methyltransferase (ptaH or ptaI) to form isosulochrin (PubMed:24302702).  Chlorination of isosulochrin by ptaM in the cyclohexadienone B ring then produces chloroisosulochrin (PubMed:24302702).  PtaE is responsible for the oxidative coupling reactions of both benzophenones isosulochrin and chloroisosulochrin to RES-1214-1 and pestheic acid respectively, regardless of chlorination.
What are the official names of this protein?
Probable decarboxylase ptaD, Pestheic acid biosynthesis cluster protein D.
What is the protein family that this protein belongs to?
Belongs to the tpcK family.
Protein: AMPA_BURP1
Sequence: MDFSIKGCDWSKGTANGFLTGKSDCIVLGVFEAQTLSGAALDIDEATKGLVSRVIKAGDIDGKLGKTLFLHEVSGIGASRVLLVGLGRQDAFSQKAYGDAAKAAWRALLGTKVVQVTFTLAQLPVPERASDWGVRAAILALRNETYKFTQMKSKPDAGAPALKRVVFSVDPADDKAAKVAAKQAVALANGMDLTRDLGNLPGNVCTPTYLANTAKKIAKDWGLKVDVLGLKQIQALKMGSFLSVAKGSVEPPQFIVLQYRGAAAKAAPVVLVGKGITFDSGGISLKPGEGMDEMKYDMCGAGSVLGTMRAVAEMGLKINVVAIVPTCENMPAGNANKPGDIVTSMKGLTIEVLNTDAEGRLILCDALTYAERFKPAAVIDVATLTGACIIALGHHNTGLFSKDDALAGELLDASREAGDPAWRLPLDDEYQDQLKSNFADLANIGGRPAGSVTAACFLSRFAENYPWAHLDIAGTAWKSGAAKGATGRPVPLLAQFLIDRAGA
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DYF4_CAEEL
Sequence: MKTIWLLLATCIHVFAHDELYILIDEVSLYNCRGVKNEITVKEEDVQIVNERGNRVYYIRAPGNYSLDFKKIKVKQNFGFLAGEIGVTLQVPVLEGPAGIRFDLPYTMVPETTLLSQKCDDFSGVIERNGRTYCRYCDLCHVSQAVENELASGRHQFLSQSENDTPISKCYNIESNEYDFRRTIQLPSRSQLEGLIRSKAQGIDDEIKKRLNKGRGRFQVFLNLITSDKPAISLNRWMAGSKDCECCFNRNAPHCDSLSYLYCNMEDCKTGWALQCLHKSAKVAACYTVEFNYRMTTSYSDVLEFLRENNYPNQDSQYTQPNQPLVPTTRRPVTPSFEARQANQLQMTQACVESMPSRMTHLKRYCTIFWNEKLCCEHCPDIC
What is the function of this protein?
Required for the localization of daf-6 to the socket glial channel and the sheath lumen (PubMed:34115759).  In association with daf-6, plays a role in dendrite extension and ciliogenesis to ensure the formation of glial channels in amphid and phasmid ciliated sensory neurons (PubMed:34115759).
What are the official names of this protein?
Protein dyf-4, Abnormal dye filling protein 4.
What are the subcellular locations of this protein?
Secreted. Note=Secreted into the sensory compartment region in both amphids and phasmids.
Protein: VPS45_ARATH
Sequence: MVLVTSVRDYINRMLQDISGMKVLILDSETVSNVSIVYSQSELLQKEVFLVEMIDSISVSKESMSHLKAVYFIRPTSDNIQKLRYQLANPRFGEYHLFFSNLLKDTQIHILADSDEQEVVQQVQEYYADFVSGDPYHFTLNMASNHLYMIPAVVDPSGLQRFSDRVVDGIAAVFLALKRRPVIRYQRTSDTAKRIAHETAKLMYQHESALFDFRRTESSPLLLVIDRRDDPVTPLLNQWTYQAMVHELIGLQDNKVDLKSIGSLPKDQQVEVVLSSEQDAFFKSNMYENFGDIGMNIKRMVDDFQQVAKSNQNIQTVEDMARFVDNYPEYKKMQGNVSKHVTLVTEMSKLVEARKLMTVSQTEQDLACNGGQGAAYEAVTDLLNNESVSDIDRLRLVMLYALRYEKENPVQLMQLFNKLASRSPKYKPGLVQFLLKQAGVEKRTGDLFGNRDLLNIARNMARGLKGVENVYTQHQPLLFQTMESITRGRLRDVDYPFVGDHFQQGRPQEVVIFMVGGTTYEESRSVALQNATNSGVRFILGGTAVLNSKRFLKDLEEAQRISRSGSHMV
What is the function of this protein?
Involved in the protein transport to the vacuole, probably at the level of vesicle fusion at the trans-Golgi network (TGN) and not in transport from the TGN to the prevacuolar compartment, by promoting the recycling of vacuolar sorting receptors back to the TGN (PubMed:19251905).  Involved in early endosomal vesicle trafficking, particularly at the trans-Golgi-network/early endosome (TGN/EE) thus residing in early endocytic route (PubMed:23737757).  Together with BIG5/BEN1 required for polar PIN-FORMED (PIN) proteins localization, for their dynamic repolarization, and consequently for auxin activity gradient formation and auxin-related developmental processes (e. g.  embryonic patterning, organogenesis and vasculature venation patterning) (PubMed:23737757).  Necessary for pollen germination and for cell expansion (PubMed:19251905).  Binds syntaxins.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 45 homolog, AtVPS45, Protein BFA-VISUALIZED ENDOCYTIC TRAFFICKING DEFECTIVE 2.
What is the protein family that this protein belongs to?
Belongs to the STXBP/unc-18/SEC1 family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Early endosome. Note=Binds to trans-Golgi network membranes through interaction with other proteins.
Protein: OSTB_LEUER
Sequence: MSGLLKYLFGCFILCLLLQGKTHMTSATISKPHETIDIEKQNMTGERNSTLAQQLSFPMEDPTNWNYAILALAFVVLFLAFLILAQNSRANRTRKMKALNGAGGRNETEADSTQKAMMQYVVEVDNLAETDQMLQSKPTYISLNQVAQTSSPKVLPKEGQILVEWKDGNIGFLYTDSKEDDV
What is the function of this protein?
Essential component of the Ost-alpha/Ost-beta complex, a heterodimer that acts as the intestinal basolateral transporter responsible for bile acid export from enterocytes into portal blood.  Efficiently transports the major species of bile acids.  May modulate slc51a glycosylation, membrane trafficking and stability activities (By similarity).  Able to transport taurocholate, estrone sulfate, digoxin, and prostaglandin E(2), but not p-aminohippurate or S-dinitrophenyl glutathione.
What are the official names of this protein?
Organic solute transporter subunit beta, OST-beta, Solute carrier family 51 subunit beta.
What is the protein family that this protein belongs to?
Belongs to the OST-beta family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: Y3412_METJA
Sequence: MKSKKPNFEFELKNYAIWYDINDAIIKESLCRYIKNILRKEFCGNCSKIKDIELKQKGKDIVVHLQFKLG
What are the official names of this protein?
Uncharacterized protein MJECS12.
Protein: RLME_SHESW
Sequence: MSGKKRTASSNRWMLEHFDDHYVKLAQKRGLRSRAAFKLEELQQKDQLIRPGMTVVDLGAAPGGWSQVAVKLVGDRGKVIACDILPMDPIVGVDFLQGDFREEKVLEALLTRVGADKVDVVLSDMAPNMSGSDGVDQPRAMYLVELALDMCHQVLAPNGSFAVKVFQGEGFDEYMKAVKEAFKVVKTRKPDSSRARSREVYLVATGYKL
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPSD_LIMPA
Sequence: YLVNPAGYAALGAYMFLLILIGFPVNFLTLYVTLEHKKLRTPLNYILLNLAVADLFMVLGGFTTTMYTSMHGYFVLGRLGCNLEGFFATLGGEIALWSLVVLAIERWIVGLKPIRNFRFTEDHAIMGLAFSWVMALSCAVPPLAGWLRYIPEGIQGSCGVDYYTRAEGFNNESFVIYMFTVHFLIPLSVIFFCYGRLLCAVKEAAAAQQESETTQRAEKEVSRMVVIMVIGFLVCWLPYASVAWWIFCNQGSDFGPIFMTLPSFFAKRPAIYNPMIYICMNKQFRHCMI
What is the function of this protein?
Photoreceptor required for image-forming vision at low light intensity.  While most salt water fish species use retinal as chromophore, most freshwater fish use 3-dehydroretinal, or a mixture of retinal and 3-dehydroretinal (By similarity).  Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins.  Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity).
What are the official names of this protein?
Rhodopsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell projection, cilium, photoreceptor outer segment. Note=Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to disk membranes in the rod outer segment (OS) photosensory cilia.