PharMolix/UniProtQA huggingface dataset:
Protein: DAPE_HAEIN
Sequence: MKEKVVSLAQDLIRRPSISPNDEGCQQIIAERLEKLGFQIEWMPFNDTLNLWAKHGTSEPVIAFAGHTDVVPTGDENQWSSPPFSAEIIDGMLYGRGAADMKGSLAAMIVAAEEYVKANPNHKGTIALLITSDEEATAKDGTIHVVETLMARDEKITYCMVGEPSSAKNLGDVVKNGRRGSITGNLYIQGIQGHVAYPHLAENPIHKAALFLQELTTYQWDKGNEFFPPTSLQIANIHAGTGSNNVIPAELYIQFNLRYCTEVTDEIIKQKVAEMLEKHNLKYRIEWNLSGKPFLTKPGKLLDSITSAIEETIGITPKAETGGGTSDGRFIALMGAEVVEFGPLNSTIHKVNECVSVEDLGKCGEIYHKMLVNLLDS
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.  It can only hydrolyze L,L-N-succinyl-diaminopimelic acid (L,L-SDAP) and is inactive toward D,L-, L,D-, and D,D-SDAP.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: SERC_ALBFT
Sequence: MNRPYNFSAGPAAMPQEVLTEAAAEMLDWHGSGMSVMEMSHRGREFVSIYEQAHLDLRELLAVPDSFKILFMQGGGLAENAIVPLNLSARVSPAGAAGSADFVVTGGWSLKSQQEARKYCTVNIAASNESDGHTTLPGPASWQLSHGASYVHICSNETIHGVEYHTLPDLQALGSEAALVVDCSSHVASRPIDWSRVGLAFAGAQKNLGPAGLTLVVVREDLLGHALAVCPSAFNYKTVADNQSMFNTPPTYAIYIAGLVFQWLKRQGGIAAMEARNQAKAALLYDAIDNSQLYYNKVAPNCRSRMNVPFFLRDESLNDAFLAGAREHGLLQLKGHKSVGGMRASIYNAMPMEGVQALVNYLHEFQKRRS
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1494_STRPF
Sequence: MDPKKIARINELAKKKKTVGLTGPEKVEQAKLREEYIEGYRRSVRHHIEGIKLVDEEGNDVTPEKLRQVQREKGLHGRSLDDPKS
What are the official names of this protein?
UPF0291 protein MGAS10750_Spy1494.
What is the protein family that this protein belongs to?
Belongs to the UPF0291 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN614_HUMAN
Sequence: MIKTQESLTLEDVAVEFSWEEWQLLDTAQKNLYRDVMVENYNHLVSLGYQTSKPDVLSKLAHGQEPWTTDAKIQNKNCPGIGKVDSHLQEHSPNQRLLKSVQQCNGQNTLRNIVHLSKTHFPIVQNHDTFDLYRKNLKSSLSLINQKRRHGINNPVEFIGGEKTLLHGKHERTHTKTRFSENAKCIHTKFQVFKHQRTQKIEKPHACIECEQTFLRKSQLIYHENICIQENPGSGQCEKLSRSVLFTKHLKTNTTDKICIPNEYRKGSTVKSSLITHQQTHTEEKSYMCSECGKGFTMKRYLIAHQRTHSGEKPYVCKECGKGFTVKSNLIVHQRTHTGEKPYICSECGKGFTMKRYLVVHQRTHTGEKPYMCSECGKGFTVKSNLIVHQRSHTGEKSYICSECGKGFTVKRTLVIHQRTHTGEKSYICNECGKGFTTKRTLIIHQRTHTGEKPYECNECGKAFSQKICLIQHERCHTGKTPFVCTECGKSYSHKYGLITHQRIHTGEKPYECNECGKAFTTKSVLNVHQRTHTGERPYGCSDCEKAFSHLSNLVKHKKMHTREMGRISQVENSCNGESQLLPYK
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 614.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PAX_I85A7
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDFHFIDERGESIIVESGDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFVSPKEVKRQLKKDLRSQEPCAGLQTKVSRRTSPALKTLEPMWMDSNRTAALRASFLKCQKK
What is the function of this protein?
May play a role in the modulation of host immune response.
What are the official names of this protein?
Protein PA-X.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA-X family.
Protein: FLHA_PROMI
Sequence: MANLASLLRLPGNWKSSQWQILAGPVLILLILSMMVLPLPPFLLDLLFTFNIALSIMVLLVAMFTRRTLDFAAFPTILLFTTLLRLSLNVASTRIILMEGHTGSAAAGRVVEAFGHFLVGGNFAIGIVVFIILILINFMVITKGAGRIAEVGARFVLDGMPGKQMAIDADLNAGIINEEEAKKRRKEVSLESDFYGSMDGASKFVRGDAIAGLMILVINVVGGLVVGVAQHNMALNDAASTYTLLTIGDGLVAQIPALIISTAAGVIVTRVATDEDVGQQMVTQLFDNPRVLMLTAGVLGLLGLVPGMPNFVFLFFTAALAGLGWYILKRHSSPQVQQQKELEQVEKQNRVVEASWEDVQLEDPLSMEVGYRLIPMVDNRQNGELLGRISGIRKKFAQEMGYLPPVVHIRDNMEVKPSSYRILMKGVEIGHGEAHPGRWLAINPGNAVGTLEGDNTQEPAFGLPAVWIDDSLREQAQVQGYTVVAASTVIATHFNHVLNQYAAELFGRQEAQMLFDRVSKELPKMTENMIPDMLSLTVLHKVLQNLLAEQVPIRDMRTILEALAEHAPEQKDPAELTAVVRVALRRAITQHWFGDKEEIQVIGLDAGLERLLLQAMQSGGGLEPGLAENIEQQALDAVRRQEMSGGVPVLLVNHALRSLLSRFLRRSLPQLAVLSNMEISEGRHIRMTSMIGGQNN
What is the function of this protein?
Required for formation of the rod structure of the flagellar apparatus.  Together with FliI and FliH, may constitute the export apparatus of flagellin (By similarity).
What are the official names of this protein?
Flagellar biosynthesis protein FlhA.
What is the protein family that this protein belongs to?
Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MCM6_RAT
Sequence: LRDEEQTAESIKNQMTVKEWEKVFEMSQDQNLYHNLCTSLFPTIHGNDEVKRGVLLMLFGGVPKTTGEGTSLRGDINVCIVGDPSTAKSQFLKHVDEFSPRAVYTSGKASSASGLTAAVVRDEESHEFVIEAGALMLADNGVCCIDEFDKMDMRDQVAIHEAMEQQTISITKAGVKATLNARTSILAAANPVSGHYDRSKSLKQNINLSAPIMSRFDLFFILVDECNEVTDYAIARRIVDLHSRIEESIDRVYSLDDIRRYLLFARQFKPKISKESEDFIVEQYKRLRQRDGSGITKSSWRITVRQLESMIRLSESMARMHCCDEVQPKHVKEAFRLLNKSIIRVETPDVNLDQEEEIQMETDEGPGGINGHADSPAPVNGFNGSGEDASQETVPKPSLRLAFAEYCRISNLIVLHLRKMEEEEDESALKRSELVNWYLKEIESEIDSEEELINKKRIIEKVVHRLTHYDHVLIELTQAGLKGSSEGSESYEEDPYLVVNPNYLLED
What is the function of this protein?
Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells.  Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.  The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit.  The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
What are the official names of this protein?
DNA replication licensing factor MCM6, Intestinal DNA replication protein.
What is the protein family that this protein belongs to?
Belongs to the MCM family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Binds to chromatin during G1 and detach from it during S phase.
Protein: POXP_PENO1
Sequence: MPVQPCSLPAGFLPAAVSLPSQQTVIAEDETGKATIYHDAPLPIPEPHMVLVKTIAVSINPCDWKMPSRFPAPGARIGCDFAGIVLSIGPEAARIRRDLRIGDRVCGGIHGSNPIDLPSGSFSQYVAAHADLLLKLPNKLSFAQGAVLGGSVFATLWIALYESLGLEGTPDMPLQDDPPPVLVYGGSTSTGTAALQILRLSGYRPIATCSPHNNDLVRAAGAEKVFDYRSETCAADIKSYTNGRLRHVLDIITDLQSQLICYDTFSRVGGKYTCLEQPAEELHLRRTVRKEMIVGLAASGKEIALADGYERTANPQLRARSGEFFQTIQRLVDEGKFVPHPTRTVEGGFEGILKCLDILKSGGTSGEKLVVFLDRENP
What is the function of this protein?
Trans-enoyl reductase; part of the gene cluster that mediates the biosynthesis of oxaleimides, cytotoxic compounds containing an unusual disubstituted succinimide moiety (PubMed:28365998).  The first step of the pathway is provided by the HR-PKS poxF that serves in a new mode of collaborative biosynthesis with the PKS-NRPS poxE, by providing the olefin containing amino acid substrate via the synthesis of an ACP-bound dec-4-enoate (PubMed:28365998).  The cytochrome P450 monooxygenase poxM-catalyzed oxidation at the alpha-position creates the enzyme-bound 2-hydroxydec-4-enoyl-ACP thioester, which may be prone to spontaneous hydrolysis to yield 2-hydroxydec-4-enoic acid due to increased electrophilicity of the carbonyl (PubMed:28365998).  2-hydroxydec-4-enoic acid can then be further oxidized by poxM to yield the alpha-ketoacid 2-oxodec-4-enoicacid, which is reductively aminated by the aminotransferase poxL to yield (S,E)-2-aminodec-4-enoic acid (PubMed:28365998).  The Hybrid PKS-NRPS synthetase poxE then performs condensation between the octaketide product of its PKS modules and the amino group of (S,E)-2-aminodec-4-enoic acid which is activated and incorporated by the adenylation domain (PubMed:28365998).  The resulting aminoacyl product can be cyclized by the Diels-Alderase PoxQ and reductively released by the reductive (R) domain of poxE to yield an aldehyde intermediate (PubMed:28365998) (Probable).  The released aldehyde is then substrate for a Knoevenagel condensation by the hydrolyase poxO followed by an oxidation at the 5-position of the pyrrolidone ring (PubMed:28365998).  The presence of the olefin from the amino acid building block allows for migration of the substituted allyl group to occur (PubMed:28365998).  This allylic transposition reaction takes place in a conjugate addition, semipinacol-like fashion to yield a succinimide intermediate (PubMed:28365998).  Iterative two-electron oxidations of the C7 methyl of the succinimide intermediate to the carboxylic acid can be catalyzed by one of two remaining cytochrome P450 monooxygenasess poxC or poxD to yield oxaleimide A (PubMed:28365998).  Subsequent oxidation yields the maleimide scaffold oxaleimide I (PubMed:28365998).  Both oxaleimide A and oxaleimide I can undergo oxidative modifications in the decalin ring to yield the series of products oxaleimides B to H (PubMed:28365998).
What are the official names of this protein?
Trans-enoyl reductase poxP, Oxaleimides biosynthesis cluster protein P.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: HSLO_CHRVO
Sequence: MNMNHHDKLQRFLFDGAPVRGALVRLDGAWQQVLARRAYPQALKTVLGEMMAASVLMAANLKFDGSLILQIHGTGALKLAVVECNNDRTVRATAKWDGDLDGKPLKALLGEGGKFVLTLEPRLDKNQTWQGIVALEGDSVGQMLENYMLRSEQLDTALVLASGDEAAAGMLLQRLPEGHGEAEGWDRVQMLGRTLKAEELLGLGAEDILHRLFHEEQVRVFEQETVSFNCNCSRERVSNMLTMLGGQEVGDVLLEQGSVEIVCDYCNQRYVFDEEDANQLFDYDVVAAAREARH
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EM6_ARATH
Sequence: MASQQEKKQLDERAKKGETVVPGGTGGKSFEAQQHLAEGRSRGGQTRKEQLGTEGYQQMGRKGGLSTGDKPGGEHAEEEGVEIDESKFRTKT
What is the function of this protein?
It is thought to provide protection for the cytoplasm during the desiccation stage of embryo development.
What are the official names of this protein?
Em-like protein GEA6.
What is the protein family that this protein belongs to?
Belongs to the small hydrophilic plant seed protein family.
Protein: TRUB_DEIRA
Sequence: MPVIAADKPLHLTSHDVVNRARRALGTKRVGHTGTLDPLATGVVVLCVDDSTKLVQFMEHDTKEYLAWVSLGAGTPTLDAEGPIEQQAEVPPLDEDHLREVLKGFLGPQQQIPPQYSAIQIGGQRAYAVARAGGQLDLPARDVEIHELELIGMFPSVQAAPRTFDPQSWTPAAAGLTFTLPEPLGEFPTLLLRAHVGSGTYLRSLARDLGAALGVPAHLGGLVRTRAGRYSLRDAVSLENLTEAPTIPDLDALDFPRIEADERLARELRQGKRPAHPQRGRAVVTLGGELVAVVDGDGEHLKVVRAWA
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: CPXS1_SYNJA
Sequence: MNALQKFHHFFNCCIGAWHTERTYHYLDRGEVERSRTDFTIRTLTPELKEKVLADNNYPNHGVDGFLGFHLAFETVSEKGEEAGQELNMLFVPRREGPRGLEGDYLRDRAYEEDRPIVASFRFDPGSLQLVMTTTYTRVVAVDTITLLNPRLRLRQILTYQRPPHGQPLEELLLVGFGVEQKLT
What is the function of this protein?
Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins.
What are the official names of this protein?
Chromophore lyase CpcS/CpeS 1.
What is the protein family that this protein belongs to?
Belongs to the CpcS/CpeS biliprotein lyase family.
Protein: LUTA_BACC4
Sequence: MKVTLFVTCLVDMFETNVGKATVEVLERLGCEIEFPEAQVCCGQPAYNSGHVEAAKEAMKHMIETFEDAEYIVTPSGSCATMFHEYPHVFKDDPKWAKRAQKVADKTYEFTQFIVDVLKVTDVGASLPGIATIHKSCHMTRMLGVKEAPGILLSNVKGLTVRDLPNVQNCCGFGGTFSVKMTPISEQMVDEKVDSVMETGADYLIGADCGCLLNIGGRIERLGKEVKVMHIAEVLNSRS
What is the function of this protein?
Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source.
What are the official names of this protein?
Lactate utilization protein A.
What is the protein family that this protein belongs to?
Belongs to the LutA/YkgE family.
Protein: CAPP_AERS4
Sequence: MNEKYAALRANVGMLGQLLGKSIKDHQGQAFLDKIETIRQLAKSSRKGNEADRERLLETLRTLSDDELLPVARAFSQFLNLANVAEQFHTISRRCEEQVCTPDPLEQMFAKLKASNLSQEAIIQAVRELDIDLVLTAHPTEVTRRTLIHKHVQLNDCLEALELSDLLPRERDKILNRIEQLVNQAWHTNEIREQRPTPVDEAKWGFAVVENSLWPAIPEFMRNLDERLQQHLGVRLPLDAAPVKFTSWMGGDRDGNPFVTAKVTAEVLELGRWMAVSLFYKDIKELTSELSMSDCTDAVRERVGDHPEPYRALVRELREALRETQEYLTAKVQGQVSESRDLITTTAQLREPLELCYHSMHACGMGNIADGMLLDVLRKLACFGIHLVKLDIRQDGERHGQVFSELTRYLGMGDYAEWSEDDKQAFLLNELNSRRPLIPTDWEPSDETRETIDTCRVIAQHDPDAFGIYIISMAGAPSDVLAVQLLLKEAGCKFRMPVAPLFETQEDLMAGTAVMERLLSVDWYRGYIQGRQYVMIGYSDSAKDAGMMAAGWAQYAAMESLVALAEASNLRLTLFHGRGGTVGRGGAPAHQAILSQPPGSLRGGLRVTEQGEMIRFKFGLPKVAIHSLNLYTSAVLEGNLLPPPKPKESWRAVMEQLATVSCDHYRSIVRGHPDFVPYFRAATPEMELGKLPLGSRPAKRKPNGGVESLRAIPWIFAWTQNRLMLPAWLGAHKGLEHAITDGQKSVLEEMSRQWPFFRTRLEMLEMVFLKADLWLAEYYDTRLVPQELWNLGKQLRQELADAIQIVLQLRPQGDLLDDQPWIKESINLRNPYTDPLNVLQVELLGRSRSHTETLHPELDQALMVTIAGIAAGMRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: ATPA_ORYSI
Sequence: MATLRVDEIHKILRERIEQYNRKVGIENIGRVVQVGDGIARIIGLGEIMSGELVEFAEGTRGIALNLESKNVGIVLMGDGLMIQEGSFVKATGRIAQIPVSEAYLGRVINALAKPIDGRGEIVASESRLIESPAPGIISRRSVYEPLQTGLIAIDSMIPIGRGQRELIIGDRQTGKTAVATDTILNQKGQDVICVYVAIGQRASSVAQVVTTFHEEGAMEYTIVVAEMADSPATLQYLAPYTGAALAEYFMYRERHTLIIYDDLSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNSLLGEGSMTALPIVETQSGDVSAYIPTNVISITDGQIFLSADLFNAGIRPAINVGISVSRVGSAAQIKAMKQVAGKSKLELAQFAELQAFAQFASALDKTSQNQLARGRRLRELLKQSQANPLPVEEQIATIYIGTRGYLDSLEIGQVKKFLDELRKHLKDTKPQFQEIISSSKTFTEEAEILLKEAIQEQLERFSLQEQT
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, chloroplastic, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: PSBL_CUSEX
Sequence: MTQSNPNEQNVELNRTSLYWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid membrane; Single-pass membrane protein.
Protein: ATPA_RICPU
Sequence: MKLKPIEVAEILQKEIANINCLSELEEVGQVITVGDGIAQIYGLANVKSGEVVEFKSGVKGLVLNLENDSVGAVIMGDDNQVQQGDNVKRTKEVLEVPVGKALLGRVVDALGNPIDGKGDIASKEYRHIEMKAPGIIERTSVSEPVQTGIKAIDSLIPIGRGQRELIIGDRQTGKTAIAVDTIINQKQAHSLTNESDKIYCIYVAIGQKRSSVAQIVKKLEDAGAMDYTLIVSATASEAAALQFIAPYSACSMGEYFRDNGMHALIIYDDLSKHAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAAKMSEAKGSGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLESELFYKGVRPAVNVGISVSRVGSAAQIKAMKQVAGSVKLELAQFRELESFSQFGSDLDPATKVQIDHGKRLVEILKQAQYHPFPVEEQIVSIYVGTKKYLNDVPLQQVKEFEDKMLTEIRLNKKDILESIKNEQCITEETEQKLKAFLENFVKEFVK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GLNE_SHEWM
Sequence: MENISNKPLSAIISEVADRYWQRINDVFPELANELTKEQGEELYRIMGLSDFIADQLCRHPQWILSLFNGELNNLSRSEFDKDLHGLLSECQSEDEANRVLRCYRNKQMVRLAWRDFLGYASLENSLLDLSALAEALIISARDWLYIQACKQYGTPMDSEGNPQPLIILGMGKLGGRELNFSSDIDLIFTFPEHGETQGGRRAIENQQFFIRMGQRLVNMLHQVTVDGFVYRVDMRLRPYGESGPLVVSFSGLEDYYQEQGRDWERYAMVKARALGPWTAFSDELHSMLRPFVYRRYIDFSAIESLRKMKQLITQEVRRRQLTDNIKLGAGGIREVEFVVQSFQLIRGGREPSLRQQSLFAAIDTLYQLGQLEYLAVDELKQSYLLLRRVENLLQGIGDQQTQTLPDSGLNWYRLCHCMGMASEAELRTHIESAMSKIHRHFIETVGGRTQDEGADLWTQQLWIAYEDDDAQTLIKEQMIDDPELWPQLKSWRETVANRSIGPRGRDTLDKLMPWLLREFTNLPTPSDALNSVSKVIDQILTRTTYLELLYENPGARQQLVSLCCASPWIAAQLAKFPMLLDELIDPTQLYDTTSLDDYGSELRQYLLRVPEEDMEQQMEALRQFKLSQQLKIAAADVTGVLPVSQVSDHLTLLSEAIIEQVVMQAWQQVTARHGVPAYLEEGVTGFAVIGYGKAGGIELGYGSDLDLVFLHSFSREKYPDQGETDGDRPIEVGHFYLKLAQRILHLFSTRTTSGELYEVDMRLRPSGASGLLVSEIEYFGEYQREEAWTWEHQALVRARFMFGSNGLSSRFSELRSEVLQLARDGSDLAKAVRDMRTKMRDHLLKVKTGHFDLKQSAGGIADIEFIAQYLVLANANQHNELSFWSDNIRIFTGLGELGILAHADVESLIQAYLFLRDESHRQTLQQKPGELPLDLVAEHANRVMDIYQRILVD
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia.  When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity.  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity.  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.
Protein: METXS_BURM9
Sequence: MESIGVVAPHTMHFAEPLRLQSGSVLGNYQLVVETYGELNAARSNAVLVCHALNASHHVAGVYADDPRSTGWWDNMVGPGKPLDTNRFFVIGVNNLGSCFGSTGPMSIDPATGTPYGARFPVVTVEDWVHAQARVADAFGIERFAAVMGGSLGGMQALAWSLLYPERVAHCIDIASTPKLSAQNIAFNEVARSAILSDPDFHGGDYYAHGVKPRRGLRVARMIGHITYLSDDDMAEKFGRALRRADGALDAYNFNFDVEFEVESYLRYQGDKFADYFDANTYLLITRALDYFDPAKAFNGDLSAALAHTKAKYLIASFMTDWRFAPARSREIVKALLDNRRSVSYAEIDAPHGHDAFLLDDARYHNLVRAYYERIAEEVGA
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOB_PROMH
Sequence: MDYTLTRIDPNGENDRYPLQSQEIVSDPLDAHVHRSVYMGKLEHALHDVVNWGRKNSLWPYNFGLSCCYVEMVTSFTAVHDVARFGSEVLRASPRQADFMVVAGTCFTKMAPVIQRLYDQMLEPKWVISMGACANSGGMYDIYSVVQGVDKFIPVDVYIPGCPPRPEAYMQALMLLQESIGKERRPLSWVVGDQGVYRANMQSERERKHGERIAVKNLRTPDEI
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y3551_BACAH
Sequence: MGFPKVERLLINYKTLDEFKKFKGCGAQELSMLEELQANIIENDSESPFYGIYYGGSLIARMSLYMKRNGGEPFEITGTYLELYKLEVLPNFQKQGFGEMLVNYAKGLQFPIKTIARIHSAGFWDKLNFQPVSVPDGDFYVWHPEVNLNTVTNEESA
What are the official names of this protein?
Uncharacterized N-acetyltransferase BALH_3551.
Protein: GTAB_STAHJ
Sequence: MKQIKKAIIPAAGLGTRFLPATKAMPKEMLPILDKPTIQYIVEEASRAGIEDIIIVTGKHKRAIEDHFDNQKELEMVLEEKGKDDLLEKVQYSTDLANIFYVRQKEQKGLGHAIHTARQFIGNEPFAVLLGDDIVESETPAIKQLMNVYEETGHSVIGVQEVPESVTHRYGIIDPLEKEGRRYEVKQFVEKPKQGTAPSNLAIMGRYILTPEIFDYLETQKEGAGNEIQLTDAIERMNSDIPVYAYDFDGDRYDVGEKLGFVKTTIEYALKDPKMKDELIKFIKELGF
What is the function of this protein?
Catalyzes the formation of UDP-glucose from glucose-1-phosphate and UTP.  This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i. e.  a glycolipid found in the membrane, which is also used as a membrane anchor for lipoteichoic acid (LTA) (By similarity).
What are the official names of this protein?
UTP--glucose-1-phosphate uridylyltransferase, Alpha-D-glucosyl-1-phosphate uridylyltransferase, UDP-glucose pyrophosphorylase, UDPGP, Uridine diphosphoglucose pyrophosphorylase.
What is the protein family that this protein belongs to?
Belongs to the UDPGP type 2 family.
Protein: TIG_PASMU
Sequence: MSFTIETTQGLERRVQITVPADTVEGAVREELKRVAKTARVDGFRKGKVPPHIIEKRFGASVRHDVLGDVLQSHFFNVVMEQKVNLAGRPAFAVEQFEAGKDLVFTATFEVYPEVALQGLDQIKVEKPVVEISEADIDKMIDVLRKQQATWAETAEAASAEDRVVIDFVGSVDGEVFEGGKAEDFTLFMGQGRMIPGFEEGIVGHKAGEQFDIDVTFPEEYHAENLKGKAAKFAITLKKVEVMVLPELTDEFVAKFGPNTKTVDDLRNEIRKNMQRELKNALTAKVKGQVIDGLLAQNAIDVPASAVEQEIEVLRGQAAQRFGGNKEQAAQLPRELFEEQAKRRVQVGLLLAEVIASHELKVDEARAKTMIEEIASAYEQPAEVVEYYSKNKELMNNIRNVVLEEQAVDAVLAKAQVTEKAASFDDVMNPQA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase (By similarity).
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: PYRH_SALPA
Sequence: MATNAKPVYKRILLKLSGEALQGTEGFGIDASILDRMAQEIKELVELGIQVGVVIGGGNLFRGAGLAKAGMNRVVGDHMGMLATVMNGLAMRDALHRAYVNARLMSAIPLNGVCDNYSWAEAISLLRNNRVVILSAGTGNPFFTTDSAACLRGIEIEADVVLKATKVDGVFTADPAKDPSATMYDQLTYSEVLDKELKVMDLAAFTLARDHKLPIRVFNMNKPGALRRVVMGEKEGTLITE
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.