PharMolix/UniProtQA huggingface dataset:
Protein: EIF3E_SCLS1
Sequence: MADNTPTTANDFLNGAAQVAKSPEEIAKENDLLPKLITHLDRHLIFPLLQFVADQDEEPSPEITKAKFELLKKTNMTDYVASLYCEIEGVEEPPKEYATKRQEILQRLEIFGQESEKITDLLGREDVVTGLRSDKVANLEFLKKEHDVTIDMVNVLYDFGNFQYSCGNYGAAAELLYQFRVLSTDDDKVTAATWGKLACEILTGNWESAMEEVQKVKELIETKLFNKPVAQLNHRTWLIHWALFPFFNHEPARDVICDLFFSPAFINTIQTACPWILRYLTAAVITNRNRTRNTGQYQKQLKDIIRIVKQENYEYSDPVTDFIKALYLDFDFEEAQKKLSEAEEVLRSDFFLVAASENFVEAARHLISESYCKIHQRIDIKDLSARLGLNQDEGEKWIVNLIRDTRVDAKIDYKEGTVVMNHPPSSVYQQVIERTKGGFFRTQVLSAAVAK
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit E, eIF3e.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit E family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR5_VIBA3
Sequence: MSGNTSSLSYKDAGVDIDAGNALVDRIKGAVKRTRRPEVMGGIGGFGALCELPTKYKEPVLVSGTDGVGTKLRLALDLKKHDTIGIDLVAMCVNDLIVQGGEPLFFLDYYATGKLDVDTAADVVSGIAEGCVQAGCALIGGETAEMPGMYEGDDYDVAGFCVGVVEKADIIDGTKVAAGDALIAVGSSGPHSNGYSLIRKVLEVSGADKSEELEGRTIGEHLLEPTKIYIKSALKMIAEHDIHAISHITGGGFWENIPRVLPEGTKAVIDGKSWEWPAIFNWLQEKGNVETFEMYRTFNCGVGLVVALPKDQADAAVELLKAEGENAWVIGEIANAEAGEEQVEIK
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BETB_SINFN
Sequence: MKAQPKASHFIDGEYVEDTAGTVIESIYPATGEVIARLHAATPDIVEKAIAAAKRAQPEWAAMSPTARGRILKRAAEIMRERNRELSELETLDTGKPIQETIVADPTSGADSFEFFGGIAAAALNGDYIPLGGDFAYTKRVPLGVCVGIGAWNYPQQIACWKGAPALAAGNSMVFKPSENTPLGALKIAEILIEAGLPKGLYNVIQGDRSTGPLLVNHPDVAKVSLTGSVPTGKKVAAAAAAELKHVTMELGGKSPLIVFDDADLESAIGGAMLGNFYSTGQVCSNGTRVFVQRKIKDAFLARLKERTEAIVIGDPMDEATQLGPMVSKAQRDKVLSYIEQGKAEGARLVTGGGIPNAVNTEGTYIQPTVFADVTDEMTIAREEIFGPVMCVLDFDDEAEVVARANATEFGLSAGVFTADLTRAHRVVDQLEAGTLWINTYNLAPVEIPFGGSKQSGFGRENSVAALNHYTELKTVYVGMGKVEAPY
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
What are the official names of this protein?
Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: RK33_VITVI
Sequence: MAKSKDARIRVLLECTSCVRGGVNKESTGISRYITEKNRHNTPGRLELQKFCPYCYKHTIHGEIKK
What are the official names of this protein?
50S ribosomal protein L33, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YAP1_CAEEL
Sequence: MASKSIHKKHQENSQQDKNQFSVHHYLDPNQSIHALISCSEKKYEKNQNQKKNPLPSSYYHQKRNPGSSAHSPYGSVDESSRTAVSPAMDMVSNQAPIHTRQVSAPNLHTSVNNGQSSATVPHPSHHNVHHQHSKSVSALPMTIGYSPVPSHVKSVSHEANYSYAGLSEIPQQQGMMQQNREKSLSLDPMRRPFMTPQDVEQLPMPQGWEMCYDSDGVRYFKDHNSKTTTWDDPRLKQQEQTGFGLGENIGQNRYNNCYDNGHSSRSLPSIHQHQQMIPNHPQPQYSSQQQMDYIQQLQNERMMIQEKNAQLINSGLVDSPQPPYQAISPMSSTMMHSHDPNFMYQQQQQAQNSQQQQTPHTLHQIPNQYQNSQMNDDSAMEVDYSMVSHPQQLQHQHQPHMHNNMPSNYVIDDINPHEFDQYLQISNDNNRGVGSMVHHYQ
What is the function of this protein?
Plays a role in thermal stress response and in aging.
What are the official names of this protein?
Yes-associated protein homolog 1.
What is the protein family that this protein belongs to?
Belongs to the YAP1 family. Highly divergent.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell projection, cilium. Cytoplasm, cytoskeleton, cilium axoneme. Note=Cytoplasmic localization is regulated by wts-1 and ftt-2 (PubMed:23396260). Localizes in the cytoplasm when phosphorylated at Ser-104 (PubMed:23396260). Transient nuclear localization in hypodermal cells upon heat shock treatment (PubMed:23396260). Nuclear export after heat shock treatment is regulated by wts-1, ftt-2, hsf-1 and daf-21 (PubMed:23396260). During the embryonic development of dorsal epithelial cells, localizes transiently in the nucleus (PubMed:23396260). Mainly cytoplasmic during embryo elongation (PubMed:23396260). Localizes to the base of the cilium (PubMed:27930654).
Protein: ASTB_AERHH
Sequence: MKHFEVNFDGLVGPTHNYAGLSYGNVASQNNAKEASNPKEAAKQGLRKMKALTELGMTQGVLAPQERPDLATLRRLGFTGNDASVLAQAAKQAPAVLAACYSASSMWTANAATVSPSADTQDGRIHFTPANLTNKFHRSLEPEVTGRILRAVFNNDRHFYHHQHLPENDHFGDEGAANHTRLCRAYGESGVELFVYGRSAFDVSQPAPKRYPARQTLEASQAIARLHGLGDESAVFIQQNPDVIDQGVFHNDVIAVGNQNVLFFHQQAFLNTASALAEVRTKFGDGELHFIEVPTAEVSVQDAVKSYLFNTQILTLPSGEMAIIAPTECRDNPAVSAYLTKLVTLGTPIKGVHYMDVKQSMRNGGGPACLRLRVAMNDTELAAVNPACLITDSQFARLDGWVDRHYRDSLALDDLRDPALVMESRTALDELTQILKLGSVYPFQR
What is the function of this protein?
Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
What are the official names of this protein?
N-succinylarginine dihydrolase.
What is the protein family that this protein belongs to?
Belongs to the succinylarginine dihydrolase family.
Protein: GPA8_CAEBR
Sequence: MGALCSSETYMLDKETYKKQVEHNKMIEQDLDKDRKLKILKLLILGPGESGKSTTIKQIKIIHDEGYSVEEKLIRRHGIFMNILEGIEEIHLAVGRENKSYKNPLSFDHIHEVRMFTENFKKADEADKILGAEVINAIQKYVKDETVAMMLRDKTVYNIDDSTIYFLDNFSRIIQKDYLPTEEDILKSRVPTSGVIQYKIMLKNFNFKIFDVGGQRAQRRKWLHVFDDVHAVLFITSLSEYDQVLREDATVNRMKESLNLFEKICNGRYFINTAMILFLNKIDLFEIKIKHTNITVALTSYKGPQERDSALDYIRKRFVSLNKNKKRSIYEHVTCATDTEQIQVVIDSVIDVVIQHTMQKVGIQ
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
What are the official names of this protein?
Guanine nucleotide-binding protein alpha-8 subunit.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family.
Protein: ATPB_PASMU
Sequence: MATGKIVQIIGAVIDVEFPQDAVPKVYDALNVETGLVLEVQQQLGGGVVRCIAMGSSDGLKRGLSVTNTNNPISVPVGTKTLGRIMNVLGEPIDEQGEIGAEENWSIHRAPPSYEEQSNSTELLETGIKVIDLVCPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMKDSNVLDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDSTVVLSRQIASLGIYPAVDPLESTSRQLDPLVVGEEHYNVARGVQTTLQRYKELKDIIAILGMDELSEEDKLVVARARKIERFLSQPFFVAEVFNGTPGKYVPLKETIRGFKGILDGEYDHIPEQAFYMAGTIDEVLEKAKKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RMF_SHEAM
Sequence: MKRQKRDRLDRAFAKGFQAGVGGRSKEMCPYSNLDSRSQWLGGWREGVDGRITGLFTK
What is the function of this protein?
During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes).
What are the official names of this protein?
Ribosome modulation factor, RMF.
What is the protein family that this protein belongs to?
Belongs to the ribosome modulation factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANB_CAMJE
Sequence: MRKSMISFLEKKAKNEKITMVSAYDYHSARILDNSDIDIILVGDSLAMTVLGMQDTLSVTMDEMLIFTKAVSRGAKKSFVLADMPFMSYQSSDRDAILNASRFIKESHANGVKVEGGIEIASKIKLISQSGIPVVAHLGLTPQAVNMLGGYRVQGKDLQSAQKIIDDAKAVQDAGACMLVLECVPVKLAQKISSILEIPTIGIGSGKYCDGQVLVYHDLLGLNKDFKAKFVKHFDKIDPQVGVEKYRDEVKSGIFPSQEHSFDYLDDELLDKLY
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPSA_BPT7
Sequence: MASMTGGQQMGTNQGKGVVAAGDKLALFLKVFGGEVLTAFARTSVTTSRHMVRSISSGKSAQFPVLGRTQAAYLAPGENLDDKRKDIKHTEKVITIDGLLTADVLIYDIEDAMNHYDVRSEYTSQLGESLAMAADGAVLAEIAGLCNVESKYNENIEGLGTATVIETTQNKAALTDQVALGKEIIAALTKARAALTKNYVPAADRVFYCDPDSYSAILAALMPNAANYAALIDPEKGSIRNVMGFEVVEVPHLTAGGAGTAREGTTGQKHVFPANKGEGNVKVAKDNVIGLFMHRSAVGTVKLRDLALERARRANFQADQIIAKYAMGHGGLRPEAAGAVVFKVE
What is the function of this protein?
Assembles with the minor capsid protein to form an icosahedral capsid with a T=7 symmetry, about 60 nm in diameter, and consisting of 415 capsid proteins.  The major and minor capsid proteins are incorporated into the capsid in about a 90/10 ratio respectively.  Once the capsid is formed, encapsidates one single copy of the viral genome.
What are the official names of this protein?
Major capsid protein, Gene product 10A, Gp10A, Major head protein.
What is the protein family that this protein belongs to?
Belongs to the T7virus major capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: NRN1_DANRE
Sequence: MGLTLSGRYISLFLAVQIAYLLQAVRAAGKCGTVFKGFSDCLLQLGENMANYPQELDEKENLQTICTYWDDFHSCATTALADCQEGATDLWEKLKKESRNLDFRGSLFELCAGGNGAIRSSVPFGVTLLITALSALVTWMQF
What is the function of this protein?
Modulates postsynaptic dendritic arbor elaboration and synaptic maturation.
What are the official names of this protein?
Neuritin.
What is the protein family that this protein belongs to?
Belongs to the neuritin family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor. Synapse.
Protein: YGT2_YEAST
Sequence: MFFSSYYDKGNLKKNSCLAIISASSSQPKPLLTKARSNIFLALKILNNEPNLPSFLLFYASKKSKITAQITKLHIKGDLPSHRYSLRYRLNGGNFMCSIINIQQWYV
What are the official names of this protein?
Putative uncharacterized protein YGL182C.
Protein: CA226_HUMAN
Sequence: MFENLNTALTPKLQASRSFPHLSKPVAPGSAPLGSGEPGGPGLWVGSSQHLKNLGKAMGAKVNDFLRRKEPSSLGSVGVTEINKTAGAQLASGTDAAPEAWLEDERSVLQETFPRLDPPPPITRKRTPRALKTTQDMLISSQPVLSSLEYGTEPSPGQAQDSAPTAQPDVPADASQPEATMEREERGKVLPNGEVSLSVPDLIHKDSQDESKLKMTECRRASSPSLIERNGFKLSLSPISLAESWEDGSPPPQARTSSLDNEGPHPDLLSFE
What are the official names of this protein?
Uncharacterized protein C1orf226.
Protein: SYR_GEOMG
Sequence: MKDRVRSLVAEGIERCFADGSLASNQMPAIVIEKPAHAEHGDFACTVAMSMAKAERKAPRVIAETIVKHIENGESGIIGGIDIAGPGFINFRIKNEAWSRTLAVVEAAGASFGRSCAGEERKVQVEFVSANPTGPLHIGHGRGAAIGDTICRLLSASGFDVTREFYYNDAGAQIANLALSVQSRCLGIEPGDPRWPADGYQGDYIKDVARSYLNRETVDAGDQHVTAAGDPNDLDAIRRFAVAYLRREQDQDLLAFDVHFDVYSLESSLYTEGRVEEVVRRLIENGHTFEQDGALWLRTTDFGDDKDRVMRKSDGSYTYFVPDVAYHLAKWERGFTRVINEQGADHHSTITRVRAGLQALNAGIPQEWPEYVLHQMVTVMRGGEEVKISKRAGSYVTLRDLIDEVGRDATRFFFLMRKPDSQLVFDIDLAKQQSLENPVYYVQYAHARISSIFEAACDRGISVPSFPDAHVDLLETPEEIELIKLIGSFPEVIEGSALSFEPHRITYYLQELAGAFHSFYNKNRVIGEGKELSSARLFLLKGVAQVLKNGLALLGVSAPEKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_STRZP
Sequence: MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKHQRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: CSOCA_HYDCU
Sequence: MNRLKKSHRQKSLFWRPIAPNPRWQKENPTAHGSTDTGGFGYNGGNEEVKTSSTMMNGIHALVNERQNEWLRGYEVDIKSRFDNIESVLKDILAQQSQLNFVSWANQQLFAKLGVSLTEQDWQSGVQLQSQKGFQFLYGKTLFAQFMRMSEDFFVNDPLSGQRKQEAERMFKEAGFHAVGIAPCADGRLAHILSYVLRLPYALARRKAHAGVMFDVSESVRNWVFIEHTRFRDGQPNLADEPTRYLKIAVYHFSKADPTHQGCAAHGSDDHKAAQAALQKLKDFKQAIENRFGCGSTVQTLLLGLNTDDDSMKVHIPNASGEVCLDRYVETEQLYQATMNLPDSEAKQALENAIVTCNQALGSTAPQPELVKLLSWLIGNNFSQIAYVNQYENGCYSDIGHAERFIGIGNGFEEVQLRNLSYYSFLDTVEEGVNDVDVGIKIFKGLNVKKGLPIPIIIRCDYDGRVPGSKDRAEAKALRIEKALHNRYQELSAPGLLQTLPTLRDFTSCKPAERLPGLADLSAKQRTA
What is the function of this protein?
Reversible hydration of carbon dioxide.  This bacteria encodes at least 3 CA enzymes (PubMed:20400567).  Essential for chemolithotrophic carbon dioxide fixation, supplies CO(2) to RuBisCO (ribulose bisphosphate carboxylase, cbbL-cbbS) in the carboxysome (Probable).
What are the official names of this protein?
Carboxysome shell carbonic anhydrase, CsoSCA, Carbonic anhydrase, CA, Carboxysome shell protein CsoS3.
What is the protein family that this protein belongs to?
Belongs to the beta-class carbonic anhydrase family. CsoSCA subfamily.
What are the subcellular locations of this protein?
Carboxysome. Note=This bacterium makes alpha-type carboxysomes.
Protein: HIS3_AGRRK
Sequence: MNLVFNAPSTDKSELEDAGDFTPRFDDRGLITAIVTDAHDGELLMVAHMNAEALALTIKTKTAHYYSRSRGKLWKKGETSGNLQTVTEIRTDCDQDAIWLKVVVAGHDATCHTGRRSCFYRTVELEDGKPVLNVVDDHLHFDPSEIYRK
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MS5_ARATH
Sequence: MCPCVERRAPPGVYYTPPPARTSDHVAAMPMTERRRPPYSCSSSSERRDPFHIVHKVPSGDSPYVRAKHAQLIDKDPNRAISLFWTAINAGDRVDSALKDMAVVMKQLGRSDEGIEAIKSFRYLCSFESQDSIDNLLLELYKKSGRIEEEAVLLEHKLQTLEQGMGFGGRVSRAKRVQGKHVIMTIEQEKARILGNLGWVHLQLHNYGIAEQHYRRALGLERDKNKLCNLAICLMRMSRIPEAKSLLDDVRDSPAESECGDEPFAKSYDRAVEMLAEIESKKPEADLSEKFYAGCSFVNRMKENIAPGTANKNYSDVSSSPASVRPNSAGLYTQPRRCRLFEEETRGAARKLLFGKPQPFGSEQMKILERGEEEPMKRKKLDQNMIQYLHEFVKDTADGPKSESKKSWADIAEEEEAEEEEEERLQGELKTAEM
What is the function of this protein?
Essential for male fertility, especially for microspore and pollen grain production (PubMed:9750346, Ref. 2).  Involved in the regulation of cell division after male meiosis I and II to facilitate exit from meiosis and transition to G1 (PubMed:9451956, PubMed:21119056).
What are the official names of this protein?
Protein POLLENLESS 3, Protein MALE STERILE 5, Protein THREE-DIVISION MUTANT 1.
What is the protein family that this protein belongs to?
Belongs to the MS5 protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CBPI_DICDI
Sequence: MASVSEHCLNEIKPTILKCDKNKDRQYSIDEIVQLLKKNSKNPERLAVLLFKSLNKKLDESICFNDIDDREISKNCDKFQDKPEIDIESFLLRFDKNNDKMISHHELKTKLDELGCGNSKKTTDYVFEQIDTNKEGSLSYEDLEGFVKFLKQDNNKKTSLPSV
What are the official names of this protein?
Calcium-binding protein I, Calcium-binding protein 9.
Protein: KDPA_BURMA
Sequence: MNANNLLQAAIFIVVLIAAAVPVARYLTRVMDGSSAVVRVFGPLERALYRLAGIDPLTEMSWKQYALATVAFNALGVLFLYALLRVQGWLPGNPQGFGPMTVDGALNTAVSFVTNTNWQDYTPEQTVSYLAQMLGLTVQNFLSAATGIVVVLALIRGFARHTAQTIGNFWVDVTRVTLYVLVPMAAIIAALLMSQGVIQNTKAYQDVPTLQTTSYAAPRLDAQGNPVKDAKGNPVTVQTSVKAQTLAMGPVASQEAIKMLGTNGGGFFNGNSSHPYENPTPFSNFLEIFAILIIPAALCLVFGNTIGDRRQGVAVLAAMTVALAAAIGIETSAEQGGTPVLASLNVDQAASPLQAGGNMEGKETRFGIAQTGLFVVATTAASCGAVDAMHDSLTPVGGLVPMLLMQLGEVIFGGVGSGLYGMLVFALLAVFVAGLMIGRTPEYVGKKIESYEMKMVSIVVLLTPLLVLVGTSIAVLADAGRAGIANPGPHGFSEILYAFSSAANNNGSAFGGLSVNTPFYNWMTAIAMWFGRFGTIVPVLAIAGSLAAKKRIAATSGTLPTHGPLFVVLLLGTVLLVGALTYMPALALGPGVEHLMLFVGAH
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLMU_TOLAT
Sequence: MSLHVVILAAGKGTRMRSSLPKVLHPVAGRPMVSHVIDTARSLNAEKIHLVYGHGGEAMQARLNDADVEWVLQAEQLGTGHAVAQAMPTIPDHAKVLVLYGDTPLISPVTLETLLTIQPANGIGLLTVSLANPTGYGRILRADGQVVGIVEQKDATAEQQLINEVNTGVLVAPAKQLKQWLSGLTNLNAQGEYYLTDVIAAAHHSGSSIQTAQPVCAQEVEGANNRLQLAQLERFYQKRAAEQLMLEGVTLLDPARFDLRGTLQCGEDVLLDVNVIIEGQVELGHRVQIGAGCVLKNCRIADDSIISPYSIIEGSVLAEGCTVGPFARLRPGAELAAQAHVGNFVELKNARLGLGSKAGHLSYLGDSEIGANVNIGAGTITCNYDGANKHKTIIEDDVFVGSDTQLVAPVRVAKGATLGAGSTITRDVGEDELVLTRVRQHHITGWHRPVKQKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAC_IDILO
Sequence: MADTWEAAHSAIKTGIIAYPTEAVFGLGCDPRNEVAVQKLLSLKQRPAEKGLILIAADYSQLLPYVEDSAIAQDKRFSVLSHWPGPVTLILPVRKGVSTLLTGGRDTIAVRVTAHEPARALCRELGHALVSTSANLTGQEPARTAAEVRQQFGDSVDWIMDESTGGAANPTRIINPLNNQVFRDDA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_LARHH
Sequence: MTKFIFVTGGVVSSLGKGIAAASIAAILESRGLKVTMLKLDPYINVDPGTMSPFQHGEVFVTEDGAETDLDLGHYERFIHAKMKKSNNFTTGQVYESVIAKERRGDYLGGTVQVIPHITDEIKHKVREGAGDVDVAIVEVGGTVGDIESLPFLEAIRQMRSNFGRKNTLYVHLSYVPYIAAAGEIKTKPTQHSVKELREIGIQPDILICRMDRELPQDEKRKIALFCNVEENAVIGCYDADSIYKVPGMLHAQGIDDIICEHLDLSLPPADLSVWNGIIDAIEHPARSVNIAMVGKYVDLTESYKSLSEALKHAGIHTRSEVNIHYIDSEEVERDGCAALKGMDAILVPGGFGKRGVEGKIKAVRYAREHNIPYLGICLGMQMALIEYARDMAGMPGANSTEFDLETDFPVVALIDEWVNHDGKIETRDENSNLGGTMRLGGQECVLESGSLAARIYGAEHIVERHRHRYEVNNHYIDRLEAAGLKISGRSAGAEKLVETIELPNHRWFFACQFHPEFTSTPRDGHPLFKAYVEAALAYQADNK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: HSLU_BURVG
Sequence: MSTMTPAEIVSELDKHIIGQSKAKKAVAVALRNRWRRQQVTEPLRQEITPKNILMIGPTGVGKTEIARRLAKLADAPFIKIEATKFTEVGYVGRDVDSIVRDLIEISVKQTRESEMRKVRSKATDQAEDRILDILLPQPRAVGFGGNADHANDDNNATRQTFRKRLREGQLDDKEIELDLEQPSAGMDIMAPPGMEEMTEQIRSMFSNLGSGKKQRRKVKIQEALKLLTDEEAAKMLNDEEVKTKAVQNVEQNGIVFLDEIDKITSRNNEGSGGEVSRQGVQRDLLPLVEGTTVNTKYGMVKTDHILFIASGAFHLAKPSDLIPELQGRFPIRVELDSLSVEDFESILVATDASLVKQYQALLATEDVQLDFAADGIRRLAEIAYAVNEKTENIGARRLYTVIEKLLEEVSFSAGNHAGERVTIDAQYVDRALGEVSQDEDLSRYVL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GGT5_HUMAN
Sequence: MARGYGATVSLVLLGLGLALAVIVLAVVLSRHQAPCGPQAFAHAAVAADSKVCSDIGRAILQQQGSPVDATIAALVCTSVVNPQSMGLGGGVIFTIYNVTTGKVEVINARETVPASHAPSLLDQCAQALPLGTGAQWIGVPGELRGYAEAHRRHGRLPWAQLFQPTIALLRGGHVVAPVLSRFLHNSILRPSLQASTLRQLFFNGTEPLRPQDPLPWPALATTLETVATEGVEVFYTGRLGQMLVEDIAKEGSQLTLQDLAKFQPEVVDALEVPLGDYTLYSPPPPAGGAILSFILNVLRGFNFSTESMARPEGRVNVYHHLVETLKFAKGQRWRLGDPRSHPKLQNASRDLLGETLAQLIRQQIDGRGDHQLSHYSLAEAWGHGTGTSHVSVLGEDGSAVAATSTINTPFGAMVYSPRTGIILNNELLDLCERCPRGSGTTPSPVSGDRVGGAPGRCWPPVPGERSPSSMVPSILINKAQGSKLVIGGAGGELIISAVAQAIMSKLWLGFDLRAAIAAPILHVNSKGCVEYEPNFSQEVQRGLQDRGQNQTQRPFFLNVVQAVSQEGACVYAVSDLRKSGEAAGY
What is the function of this protein?
Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione-S-conjugate such as leukotriene C4 (PubMed:21447318).  Does not cleaves gamma-glutamyl compounds such as gamma-glutamyl leucine (PubMed:21447318).  May also catalyze a transpeptidation reaction in addition to the hydrolysis reaction, transferring the gamma-glutamyl moiety to an acceptor amino acid to form a new gamma-glutamyl compound (PubMed:21447318).  Acts as a negative regulator of geranylgeranyl glutathione bioactivity by cleaving off its gamma-glutamyl group, playing a role in adaptive immune responses (PubMed:30842656).
What are the official names of this protein?
Glutathione hydrolase 5 proenzyme, Gamma-glutamyl transpeptidase-related enzyme, GGT-rel, Gamma-glutamyltransferase 5, GGT 5, Gamma-glutamyltransferase-like activity 1, Gamma-glutamyltranspeptidase 5, Leukotriene-C4 hydrolase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyltransferase family.
Protein: Y2254_STAA3
Sequence: MEKVYVAGAIPEVGLKLLQEHFEVEMYEGKGLVDKDTLIKGVKNATALISLLSTNVDKDVIDAGKDLKIIANYGAGFNNIDIEYAREKSIDVTNTPKASTNATADLTIGLVLAVARRIVEGDQLSRTTGFDGWAPLFFRGREVSGKTIGIIGLGEIGSAVARRARAFDMDVLYTGPNRKEEKEREIGAKYVDLDTLLKNADFITINAAYNPKMHHLIDTEQFKMMKSTAYLINASRGPIVHEQALVQALKDNEIEGAALDVYEFEPDITDDLKSLNNVVLTPHIGNATFEARDMMSKIVANAAISAVQGEKPQFVVN
What are the official names of this protein?
Putative 2-hydroxyacid dehydrogenase SAUSA300_2254.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
Protein: DSRB_ECOUT
Sequence: MKVNDRVTVKTDGGPRRPGVVLAVEEFSEGTMYLVSLEDYPLGIWFFNEAGHQDGIFVEKAE
What are the official names of this protein?
Protein DsrB.
What is the protein family that this protein belongs to?
Belongs to the DsrB family.
Protein: LEUD_BEUC1
Sequence: MEKFTTHTGVGVPLRRSNVDTDQIIPAVYLKRVTRTGFEDALFAAWRGNETFVLNQPAYTHGSVLVAGPDFGTGSSREHAVWALKDYGFRVVIASRFADIFRGNSGKQGLLAAQVAQDDVELIWKVLENSPGTEVTVDLAAKQVTVADIVAPFQIDDYTRWRLLEGLDDIGLTLQHADEITAFEATREPWRPLTLPAKHLPAVPITAARPVA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.