PharMolix/UniProtQA huggingface dataset:
Protein: KTHY_ANAPZ
Sequence: MFITFEGIDGCGKTTQSILLAKYMSDLYGEDNVVLTREPGGTSFNELLRSVFLSVSDYKVDKLTELFLFLAMRRESFVKVVESALRANKIVISDRCVDSTVAYQGYGCGIDLDLIYKLNSLVMGIVPDMTFIIDIDIEKALSRATRNGYESNSMDFYHKVRKGFQRIAEEEKHRCVLLRCDDYEENGICDVYSVHNKIVGLLQGVLHNKMDAASSSVKV
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: SYR_DESPS
Sequence: MIRSQLKELLDRCFQEGVDNGSWSDRGAGKYTVELPKHEGQGDFSTNIALVLAGIEKRNPRELAGIVAEKLGLETAIVAGVEIAGPGFVNITIQPAVWHGVLAEVFSAGENFGRSQVGAGRKVMVEFVSANPTGPLSIGHGRQAILGDSIARLLEATNHDVFREYYYNNAGRQMRVLGESTRARYLELIGAEFSFPEDGYQGEYIIDIAQSLVDEHGEKLKDEPDVEPFKDQAEKAIFKDISGTLERMGIHFDNYYNERSLYENGHIDSVVQELRDKGLVYEKDDAVWFETTKLGQEKDRVIIKSTGEPTYRLPDIAYHREKFKRNFDWLIDIFGSDHIATVPDVLSGVEALGYDASKVTVLLHQFVTLTRDGKQVKMSTRKANFVTVDELIDVVGEDVLRFFYMLRKADSQLEFDLDLATSQSQDNPVYYVQYAHARLCSILAQSGERGIVPAEVGSSLLQRLQEPEELALLKTLSGFPAAIEGSALDLAPHKFIHYLMEFAGQFHSYYNKHKVITEDLELSQARLCLIQALQLTLQNGLHIIGLTAPKSM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FEN1_DROPS
Sequence: MGILGLSKLIADLAPQAIRESEMKHFFGRKVAIDASMCLYQFLIAVRSEGAQLATVNGDPTSHLMGMFYRTIRLLDNGIKPVYVFDGKPPDLKSGELAKRAERREEAEKALKAATDAGDDAEIEKFNRRLVRVTKEHAREAKELLSLMGVPYVDAPCEAEAQCAALVKAGKVYATATEDMDALTFGSTKLLRYLTYSEARKMPVKEFSYDKLLEGLEVNNREFIDLCILLGCDYCESIKGIGPKRAIELINNYRDIETILDNLDTSKYTVPENWNYKVARELFIEPEVADASAIDLKWTEPDEEGLVKFLCGDRQFSEERVRNGAKKLFKSKHAQTQVRLDSFFKTLPSTPNAVNAAKRKAEEAKKSANNKKAKTSGGAARGRRPK
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: HDHD3_XENLA
Sequence: MSLRLITWDVKDTLLRVRVPVGQQYYAEAKKRGLCVNPGTLETSFRNAYRSHSRLFPNYGLAQGMSSRQWWLDVVLQTFRLSGIEDSDTVQSLAKQLYQDFSTAHNWALVPGAREALDSCTNLGLRMAVISNFDRRLEELLRQCCLERYFDFVVTAESAGVAKPHLGIFHKALSLAKVPPHQAVHVGDDYVNDYCAARMVGMHSYLIHPKTPPKLQWNIPEEHVIQSPEQLIPKLVGVLKNSMT
What are the official names of this protein?
Haloacid dehalogenase-like hydrolase domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily.
Protein: URE3_PSEE4
Sequence: MELTPREKDKLLLFTAALLAERRLARGLRLNYPEAVALISAAVLEGARDGRTVAELMSLGREVLVREQVMDGVPEMLHDVQVEATFPDGTKLVTVHDPIV
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCD73_MOUSE
Sequence: MEDSFNTTSSASTFTLQSSSETMVSIQLLDFRTSLLEALEELRMRRKAETQYEEQIAKIILETQELKWQKEALQNQKEALIKQHKEAMGVLKNQLQMKMYALEEEKGKYKLATEIKEKEIEGLKETLKTLQVSQYSLQKKVSEMEQKAHLYHLAKEDYHKQLNEIEKYYAAITNQFGLVRENHVKLEQNVQEAIQLNKRLSTLNEKQESEIHSLKKELKKAASELIKSKVTCQHKMEEESIDLIIKEQKYEELQERLNMELEVNKKINEEITHIQEEKQDIIISFQHMQQLLQQETQANTEIDAELKVLRENNQTLERDNELQREKVKENEEKFLSLEKEHERALGTWKKHVEELSGEMNVIKNELSSLRETHAKLQEHYNKLCEQKKTEEYKKFQNVPELNNENSDELTRKKSENIITQKYNSGPEIWGKNTKSFCLDTEYREEEKKDLPVGKTAEDLQPFEISAKSEINTMVSQDRNQSGMSPHRVLCLDKDATDQEQTSDVTDSRKSVTVEVKDKLCLEKASGCSEFKSLNNFFLVVDESLETEMVRLEGTEGLGLLHSGGDIPLDTRSNKASSNGMSNEMAHKRNYNTDGSESNPFKQQSKLLPADLENATEKEITNQDQTKAGLDSFLDIKLNLDPCKKHGLQDSSHVTLDVKHQKIKQMVREESQCSTEPRSCYQLASKAPQKPGGTIACAAVVSPLGPSASSDNKLTALKKSENSINTLPTAAKPAPSPAERTTRTNTNDIQNSSLRNHLGASESSVSVSDFQVNQGDSHTSQAKGLKTVVPLTTSSEKQPPSESQITETPKSGLSSLVDVTGRQCMWLNNRDKTEALNGILSGGTCHEGQLEEAHLSPATPSADSVSTSARSAFDLPSPDKPEKTPGYIKFVPLSPWPKVNQTKTVGTATPSIPLFLKEKTVDLSGSRVITPVTFCKNVVLDDTRKNIESDPTSNSRAADTMSNWSIHLDPKGQPREERNATAQTVYDSSFPTEHVKAEPLISTVQQSHSQTVKVTDSPDPLTFSPGNNDWQSLVMNRLTEIEKLLSLESDNQPKRRKVEEMLDNIID
What are the official names of this protein?
Coiled-coil domain-containing protein 73.
Protein: ATPA_SYNR3
Sequence: MVSIRPDEISAILKQQIEDYDKSVSVSNVGTVLQVGDGIARVYGLDKVMAGELVVFEDGTEGLALNLEDDNVGVVLMGEGYGIQEGSTVKATGKIASVPVGEAMLGRVVNPLGQPMDGKGEIASTDVRLIENPAPGIIQRKSVHEPMQTGITAIDAMIPIGRGQRELIIGDRQTGKTAIAIDTIINQKSEDVVCVYVAIGQKAASVAQVTEVLRERGALDYTVIVAAGASEAASLQYLAPYTGAAIAEHFMYQGKATLVIYDDLTKQAQAYRQMSLLLRRPPGREAYPGDVFYCHSRLLERAAKLSDAMGKGSMTALPIIETQAGDVSAYIPTNVISITDGQVFLSSDLFNSGLRPAINVGISVSRVGGAAQTKAIKKIAGTLKLELAQFDELAAFSQFASDLDAATQAQLGRGKRLRELLKQAQFSPLLLAEQVAIVYAGTKGLLDELPVEKVTEFVRELRDYLKTSKPEFINAIQTEKVMSESSEAILKDAIKQVVSGLLVAA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: NADD_DECAR
Sequence: MSEPLGLFGGTFDPVHFGHLRLAEESIAHLGLGGVRWIPAGQPPHRGVPQVTAQQRLEMVRLAMANNARFSLDPSEVEAEAPSYTVHTLERLRRELGPLQSLVLLVGADAFAGLATWHRWRDIFALAHVAVSHRPGFPVEISSLPHELASEFTDRRRADVRGLKASPAGGIVTFAMTQLAISATQIRKLLANELSARYLLPDSVLDYIQTHSLYRNS
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: FYV10_ASPNC
Sequence: MAAELTSTRLNAENHLLLDQPLLRLPHELARRNFKSVQRLVEREKEYVLPALKETANASLSNEQTPDQALAALDAMISRMQGLKRKMENLHQEERKIQEQSRKRIQHLEKLHQIPSLADVQYDQWARVRLDRLMIDHMLRSGYIKSAQQLAREKGIEDLVDLNVFVQCQRIAESLRTGETKDALQWCGENKAALKKSQYNLEFELRLQQYIEMVRAGHKERFNDAMIHAKRYLAPYLETQSVEIHRAAGLLAFPPDTKAEPYKSMYAHERWAYLSDLFVRTHHELLSLSSRPLLHIALSAGLSALKTPSCHSAYTSSSSNSLSTTTSVCPICSTELNELARNMPYAHHTKSYVENDPIVLPNGRIYGQQRLLEMSKKVGCVEVGKVKDPTTGEVFNEGDMKKVYIM
What is the function of this protein?
Involved in the proteasome-dependent degradation of fructose-1,6-bisphosphatase.
What are the official names of this protein?
Protein fyv10.
What is the protein family that this protein belongs to?
Belongs to the FYV10 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: HYPA_LEGPC
Sequence: MHELWLCKRIVEIIKQQATGNKCRMVKKIVLEIGQLVAVDKHALNFSFKVITQGTIAQNAELSIVEIPGEAICNSCQQIVPMKQYYDECLVCGNHSLTLTKGEELKVKSMVVE
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: WZB_ECO57
Sequence: MFNNILVVCVGNICRSPTAERLLQRYHPELKVESAGLGALVGKGADPTAISVAAEHQLSLEGHCARQISRRLCRNYDLILTMEKRHIERLCEMAPEMRGKVMLFGHWDNECEIPDPYRKSRETFAAVYTLLERSARQWAQALNAEQV
What is the function of this protein?
Dephosphorylates Wzc.  Required for the extracellular polysaccharide colanic acid synthesis.  Probably involved in the export of colanic acid from the cell to medium.  Involved in protection of cells against contact-dependent growth inhibition (CDI).
What are the official names of this protein?
Low molecular weight protein-tyrosine-phosphatase Wzb.
What is the protein family that this protein belongs to?
Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
Protein: CPXK_SACEN
Sequence: MTTGEVPDLLAFDDAFAQDRHNRYARMREEPVQRIRTVNGLDAWLITRYEDVKQALLDPRIAKDFGRTQQIIEKRLADAERRPGFSPDLGPHMLNTDPPDHTRLRKLVVKAFTARRVEGLRPRIEQITDDLLDRLAGRSEVDLIDEFAFPLPITVISELMGVEDSRRDDFRSWTNVLVDGSQPEAQAQASVAMVEYLTELIAKKRTEPGDDLLTALLEAVEDGDRLSEGELIAMVFLLLVAGHETTVNLIGNCVLSLLGNPDQLAALRNDPSLLPGAIEETLRYESPVANGTFRHTAEAVRFGDVVIPEGELVWVALGAANRDGERFEDPDRFDITRETTGHVAFGHGIHFCVGAALARLEAQIAVGRLLERFPDLRMAASPDDLRWRFSVLMRGLEKLPVRPGA
What is the function of this protein?
Not known, probably involved in the catabolism of octane and guaiacol.  It displays a weak activity in the O-dealkylation of 7-ethoxycoumarin.
What are the official names of this protein?
Cytochrome P450 107B1, Cytochrome P450CVIIB1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGL2_ORYSJ
Sequence: MQFMMPLDTNACAQPMRRAGEGAGTERLMERLNIGGMTQEKALRKRCFGDGVTGTARCVFTSDADRDTPHLRTQSSRKNYADASHVSAVILGGGTGVQLFPLTSTRATPAVPVGGCYRLIDIPMSNCFNSGINKIFVMTQFNSASLNRHIHHTYLGGGINFTDGSVQVLAATQMPDEPAGWFQGTADAIRKFMWILEDHYNQNNIEHVVILCGDQLYRMNYMELVQKHVDDNADITISCAPIDGSRASDYGLVKFDDSGRVIQFLEKPEGADLESMKVDTSFLSYAIDDKQKYPYIASMGIYVLKKDVLLDILKSKYAHLQDFGSEILPRAVLEHNVKACVFTEYWEDIGTIKSFFDANLALTEQPPKFEFYDPKTPFFTSPRYLPPARLEKCKIKDAIISDGCSFSECTIEHSVIGISSRVSIGCELKDTMMMGADQYETEEETSKLLFEGKVPIGIGENTKIRNCIIDMNARIGRNVIIANTQGVQESDHPEEGYYIRSGIVVILKNATIKDGTVI
What is the function of this protein?
Involved in synthesis of starch.  Catalyzes the synthesis of ADP-glucose, a molecule that serves as an activated glycosyl donor for alpha-1,4-glucan synthesis.  Essential for starch synthesis in seed endosperm (PubMed:17406793, Ref. 13, PubMed:24747952, PubMed:27957808).  Is essential for both catalytic and allosteric regulatory properties of the cytosolic heterotetramer enzyme (PubMed:24747952).
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase large subunit 2, cytosolic, OsAGPL2, OsAPL2, ADP-glucose pyrophosphorylase AGPL2, ADP-glucose synthase AGPL2, Protein FLOURY ENDOSPERM 6, Protein GRAIN INCOMPLETE FILLING 2, Protein SHRUNKEN 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: Y977_CALBD
Sequence: MNLKQVGRFGENLAVDFLIKHGYEILRTNFRCRLGEIDIIAKEDKTIVFVEVKTRKSLKFGLPSESVNFKKQLHIKKVAEYFIAYHLSQDKYLYRFDVVEIFIDGKNNVTKINLIKDAF
What are the official names of this protein?
UPF0102 protein Athe_0977.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: UREG1_BRUAB
Sequence: MTQKNGPLRVGIGGPVGSGKTTLTEKLCKAMRDKYSVAVITNDIYTQEDALILARRQALSEDRIIGVETGGCPHTAIREDASINLQAVVEMTRRFPDLDVVFIESGGDNLAATFSPDLADLTLYVISVCQGEEIPRKGGPGITRSDFLVINKSDLAPYVHVDLEVMEADAMRMRAKRPFGFTDLHRGKGVQEIIDFIVENGGLEPRSN
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG 1.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YPI7_CAEEL
Sequence: MAVQQKRRGLSFIDAKASNVKKIAVMASTVAFEFNKATLRLRRSLHISPRSSPEVQRKATAGENSEVGSPESSLSTSRCSKRDRKLCAELSSFALYPIFGALSPSHFSSPNLLFQSEKNSSRRSFEFMQLPDTDICQIMSFLDAQSLLNLSQTCSHLRQLCLAHEDNAGKRDVTSHEITISFNQIHRRTEVRLLKRERTRTDRQFISNNIRGVLAPFSRALTKITFETTVFVTDWLDEILQLHRENRLIPLSLLFTGGALTKGHQVTGADLRSITETEFVDFVTKLQPHLQEVQLSTSRIFKISTDPSQLLGMISMLSSFGIVYERPPLHFYHEEISNAIALWKSDPLSRCCDVYMRRPHDVSSESWIKLAGSIDESRIDPYTDEVLVSQITIKHSFLVHIDLVFHFH
What are the official names of this protein?
Uncharacterized F-box protein C27F2.7.
Protein: YPPC_CHLLI
Sequence: MRVSSLTVGGYGKEVSWQAVQRASLIRIINPALPHILHDRPALARLHWAAEVTGIGLAASIKPQLTDIMIRKTACSAVALLVLIGATPAFATNGMNLEGYGAKSMAMGGTGSAYDTGNSAVMNNPATLGFMKEGTSEIGFGIRGLHPDISLDNNGITDKSDATVLHALDVLHAPRRTDHLGRRMLAQGAWAPTTATTRRCSLR
What are the official names of this protein?
Uncharacterized protein in phosphoenolpyruvate carboxykinase gene 5'region.
Protein: GCSPB_SULIN
Sequence: MVWRQAKWDEPLIFELNNSGANRQGLLINKDDEIRSEIKEMKIPKNLLRENGPNLPSLSELEVVRHFIRLSQMNFGVDVGIMPLGSCTMKYNPKIEEKATAITESHHPLEDEDHVQGILEMIYELQNWFSEITGMDECSLQVPAGSAGEFAGVLMIKKYHEDHNRNYKDTMLVADTAHGTNPASAAMAGYKVMYVKSNGEGLVDMDILREIVNDKTAGFMLTNPNTLGLFEENILEISKIIHSANAILYYDGANLNGVLGIARPGDMGFDIVHLNLHKTFAVPHGGGGPGAGAICAKGELVNYLPYPMVEKVNGKYRLSKIPKNSVGKIATFYGNVGNLARSFAYLLGLGPQGVQMVGKMSTLATNYLIAKLRDIKELELIAPNRHRKHEVVFSVKQLMENYGVSANDVAKALLDSGFYAPTIYFPPIIEEALMIEPTETESKETLDMFAEALKKIVEDAKRNPEQLLKSPSNTSIARLDQAYANHPSTITPTYRVLKLRRMGKINYLK
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 2, Glycine cleavage system P-protein subunit 2, Glycine decarboxylase subunit 2, Glycine dehydrogenase (aminomethyl-transferring) subunit 2.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. C-terminal subunit subfamily.
Protein: RLP35_ARATH
Sequence: MTGSWNPTSIIIPVTLSFLLSFIHNFADVVAAPTRHLCLPEQRDALLELKNEFEIGKPSSNDYCYRNNSRVSPHPTTESWRNNSDCCNWEGITCDTKSGEVIELDLSCSWLYGSFHSNSSLFRLQNLRVLDLTQNDLDGEIPSSIGNLSHLTSLHLSYNQFLGLIPSSIENLSRLTSLHLSSNQFSGQIPSSIGNLSHLTSLELSSNQFSGQIPSSIGNLSNLTFLSLPSNDFFGQIPSSIGNLARLTYLYLSYNNFVGEIPSSFGNLNQLIVLQVDSNKLSGNVPISLLNLTRLSALLLSHNQFTGTIPNNISLLSNLMDFEASNNAFTGTLPSSLFNIPPLIRLDLSDNQLNGTLHFGNISSPSNLQYLIIGSNNFIGTIPRSLSRFVNLTLFDLSHLNTQCRPVDFSIFSHLKSLDDLRLSYLTTTTIDLNDILPYFKTLRSLDISGNLVSATNKSSVSSDPPSQSIQSLYLSGCGITDFPEILRTQHELGFLDVSNNKIKGQVPGWLWTLPNLFYLNLSNNTFISFESSSKKHGLSSVRKPSMIHLFASNNNFTGKIPSFICGLRSLNTLDLSENNYNGSIPRCMEKLKSTLFVLNLRQNNLSGGLPKHIFESLRSLDVGHNLLVGKLPRSLIRFSNLEVLNVESNRINDTFPFWLSSLSKLQVLVLRSNAFHGPIHEATFPELRIIDISHNHFNGTLPTEYFVKWSAMSSLGKNEDQSNEKYMGSGLYYQDSMVLMNKGLAMELVRILTIYTALDFSGNKFEGEIPKSIGLLKELLVLNLSNNAFGGHIPSSMGNLTALESLDVSQNKLTGEIPQELGDLSFLAYMNFSHNQLAGLVPGGTQFRRQNCSAFENNLGLFGPSLDEVCRDKHTPASQQNETTETEEEDEEEISWIAAAIGFIPGIVFGLTIGYILVSYKPEWFMNPFGRNNRRRRNTTTH
What are the official names of this protein?
Receptor-like protein 35, AtRLP35.
What is the protein family that this protein belongs to?
Belongs to the RLP family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: MURG_LISW6
Sequence: MKVAISGGGTGGHVYPALAFIRELKKLHPEAEFLYIGTEKGLEADIVKREGIPFESIEITGFKRSLSLENVKTIMRFLSGAKKSKQILRDFKPDVVIGTGGYVCGPVVYAAAKLKIPTLIHEQNSVAGLTNKFLSRYTDKVAICFEEVSDSFASEKIVFTGNPRASEVVGVESEGALEAYGLESGKPTVLVFGGSRGARGVNEAVEAILPEWNKRDFQLLYVTGDVHYEKIKDTLADLNLGSHISVQPFIYDMPKILNAVTLVVSRAGATTLAELTALGVPSILIPSPYVTANHQENNARALEKNNAAIVITEAELKNTDLMATVDSILTDEEKLNAMKASAKQMGRPEAAAKLVEAVLGIMK
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YPK1_YEAST
Sequence: MYSWKSKFKFGKSKEEKEAKHSGFFHSSKKEEQQNNQATAGEHDASITRSSLDRKGTINPSNSSVVPVRVSYDASSSTSTVRDSNGGNSENTNSSQNLDETANIGSTGTPNDATSSSGMMTIKVYNGDDFILPFPITSSEQILNKLLASGVPPPHKEISKEVDALIAQLSRVQIKNQGPADEDLISSESAAKFIPSTIMLPGSSTLNPLLYFTIEFDNTVATIEAEYGTIAKPGFNKISTFDVTRKLPYLKIDVFARIPSILLPSKTWQQEMGLQDEKLQTIFDKINSNQDIHLDSFHLPINLSFDSAASIRLYNHHWITLDNGLGKINISIDYKPSRNKPLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPDGFDRDAKDLLIGLLSRDPTRRLGYNGADEIRNHPFFSQLSWKRLLMKGYIPPYKPAVSNSMDTSNFDEEFTREKPIDSVVDEYLSESVQKQFGGWTYVGNEQLGSSMVQGRSIR
What is the function of this protein?
Plays an essential role in the proliferation of yeast cells.  Involved in a signaling pathway, required for optimal cell wall integrity, that acts in parallel with the PKC1-SLT2-dependent pathway.  Downstream kinase in the sphingolipid-mediated signaling pathway.  Its phosphorylation is regulated by the intracellular sphingolipid concentration.  Cooperates with SLI1 in mediating resistance to the sphingolipid biosynthesis inhibitor drug myriocin (ISP-1).  Its kinase activity is essential for the resistance.  Required for both receptor-mediated and fluid-phase endocytosis, but is not necessary for receptor phosphorylation or ubiquitination.  Necessary for the internalization of plasma membrane proteins carrying different types of internalization signals.  Acts downstream of the PKH kinases to control endocytosis by phosphorylating components of the endocytic machinery.  Phosphorylation of residue Thr-504 in the activation loop is essential for activity.  phosphorylates and down-regulates flippase activator FPK1.
What are the official names of this protein?
Serine/threonine-protein kinase YPK1, Sphingosine-like immunosuppressant resistant protein 2, Yeast protein kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Intracellular localization is regulated by the intracellular sphingolipid levels. During the yeast cell cycle, distributed both on the plasma membrane and in the cytosol. Greater accumulation was detected on the plasma membrane, such as in the budding area, a daughter cell and the neck region of the mother cell in the S phase, and the septum between a mother cell and a daughter cell in the G2 phase.
Protein: KAD_CHLCH
Sequence: MKIILLGAPGAGKGTQSTSIAEHFGLQRISTGDMLRNAAKEGKPLGLEAKKIMDAGQLVSDDIIMALIKECLSKDECSCGVLFDGFPRTIGQAEALRAEEIHIDHVVEIYVQDEEIVKRMSGRRVHLASGRSYHVMFNPPKQEGLDDATGEPLVQRADDSEETVKKRLQIYHAQTAPLVEYYTMLEQKGESNAPRYHKIEGVGTVEEIRNRIFAALES
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CREL2_MOUSE
Sequence: MHLLLAAAFGLLLLLPPPGAVASRKPTMCQRCRTLVDKFNQGMANTARKNFGGGNTAWEEKTLSKYEFSEIRLLEIMEGLCDSSDFECNQLLEQQEEQLEAWWQTLKKEHPNLFEWFCVHTLKACCLPGTYGPDCQECQGGSERPCSGNGYCSGDGSRQGDGSCQCHTGYKGPLCIDCTDGFFSLQRNETHSICSACDESCKTCSGPSNKDCIQCEVGWARVEDACVDVDECAAETSPCSDGQYCENVNGSYTCEDCDSTCVGCTGKGPANCKECIAGYTKESGQCTDIDECSLEEKACKRKNENCYNVPGSFVCVCPEGFEETEDACVQTAEGKVTEENPTQPPSREDL
What is the function of this protein?
Protein disulfide isomerase (Probable).  Might play a role in the unfolded protein response (Probable).  May regulate transport of alpha4-beta2 neuronal acetylcholine receptor (By similarity).
What are the official names of this protein?
Protein disulfide isomerase Creld2, Cysteine-rich with EGF-like domain protein 2.
What is the protein family that this protein belongs to?
Belongs to the CRELD family.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: ILVD_AZOC5
Sequence: MPAYRSRTSTHGRNMAGARGLWRATGMKDGDFGKPIIAVVNSFTQFVPGHVHLKDLGQLVAREIEKAGGVAKEFNTIAVDDGIAMGHDGMLYSLPSREIIADSVEYMVNAHCADAMVCISNCDKITPGMLMAAMRLNIPAVFVSGGPMEAGKVLLSTGEKKVDLIDAMIAAADDRVSDEDVKVMERSACPTCGSCSGMFTANSMNCLTEALGLALPGNGSVLATHADRERLFVEAGHLVVDLARRYYEQDDAGVLPRTIASFKAFENAMTLDISMGGSTNTVLHLLAAANEGEVPFTMADIDRLSRKVPVLCKVAPAVANIHMEDVHRAGGIMGILGELDRAGLIHTDLPTVHAPSMKDALERWDVTRTKAESVTTFYRAAPGGVPTQVAFSQSRRWDDLDTDRASGVIRDFEHAYSKDGGLAVLFGNIAEDGCIVKTAGVDASILKFTGPARIFESQDAAVEAILANGKIKAGDIVLIRYEGPRGGPGMQEMLYPTSYLKSKGLGKACALVTDGRFSGGSSGLSIGHVSPEAAEGGAIGLVEEGDTIEIDIPNRRIHLAISDEEMARRRAAMEAKGDAAWKPKDRQRVVSQALQAYAALTTSAARGAVRDVKSLRR
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.