PharMolix/UniProtQA huggingface dataset:
Protein: RMI1_XENLA
Sequence: MMATSGIANRVKTWLISTWHVKVPDPWLEACINWIQEENGSSLLQAEINKQVFEQWLLTDLRDLEFPVLPANITDSLKCELNGFHAVQMDSLVDISLPAYSQLQKLKGKDSTNEQVTCTTQQSQKPWEAKPTRMLMLQLTDGTQHIQAMEYRPIQALNANLSPGTKMVLQGTIVCRLGVLLLKPENVKVLGGEVEALVAEYTQTKVLSRLIGVEDNTVAQHSNVQEHAAGVAAGELGQALGPSDEDLLASLEENEEFSINNGVPSESGYYSRNENSSISSSTQHQTQDSIVRCWVDDDILEFSINNGVPSESGYYSRNENSSISSSTQHQTQDSIVRQTSFPMLDQTVVHVNVANNHAIEEQFDIDDELFLEEEIQRELEEMSMSQAEVTHGSTDLPTTLSATSHASSASCTSDQNNIDIPPYTYLSTILASKSRSITCVKLKSFIVTLNGNLSHSCGLWNIKAKISDGTGYLNVEFSDDVLTELIGFTVPEMKTLKKDPSQQSTLMEGLQKCQRMLTDFCGVMTVSYNPAKEEAVVLSLQDVTEEIMQSLQKLLRS
What is the function of this protein?
Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells.  Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution.  Required for BLM phosphorylation during mitosis.  Within the BLM complex, required for BLM and TOP3A stability (By similarity).
What are the official names of this protein?
RecQ-mediated genome instability protein 1.
What is the protein family that this protein belongs to?
Belongs to the RMI1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRNHA_ARATH
Sequence: MDKRWSLQGLTALVTGGASGIGHAIVEELAGFGAKIHVCDISKTLLNQSLSEWEKKGFQVSGSVCDASNRLERETLMQTVTTIFDGKLNILVNNVGTIRTKPTIEYEAEDFSFLISTNLESAYHLSQLSHPLLKASGNGIITFISSAAGIVSFDAASIYGLTKGALNQLARNLACEWAKDGIRANAVAPNFITTALAKPFLEDAGFNEILSSRTPLGRAGEPREVASLVAFLCLPAASYITGQTICVDGGLTVNGFSYQP
What is the function of this protein?
Reductase active only on small flexible lipophilic carbonyls.  No activity with cyclic monoterpenes, tropinone, nitrogen-containing tropinone analogs, tropine or pseudotropine as substrate.
What are the official names of this protein?
Tropinone reductase homolog At2g29330.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. SDR65C subfamily.
Protein: IRC19_ZYGRC
Sequence: MAGRTILTRNAVINSTHTLIKCPEKYLLPSLEVSNLPSFVRMAYRRLFRLQSFISNRKMVRDTYGEYLRYKFKKENYDTKRSIVVGDTPKAPLREEIRNSVMFVVKAVSHLPETKDSKFAIARDNTTCRQVLKNLLTIEYEKQSLIARYRPPTKRRDMVGPYQIYRKDFTHMQELNKSAQWRVFGEFDICTVYLNEILQTRL
What is the function of this protein?
Involved in sporulation and maintenance of the mitochondrial DNA.  Is probably involved in a pathway contributing to genomic integrity (By similarity).
What are the official names of this protein?
Increased recombination centers protein 19.
What is the protein family that this protein belongs to?
Belongs to the IRC19 family.
Protein: DRL13_ARATH
Sequence: MQDLYMVDSIVSFGVEKLWKLLSQEYERFQGVEEQITELRDDLKMLMAFLSDADAKKQTRALARNCLEEIKEITYDAEDIIEIFLLKGSVNMRSLACFPGGRREIALQITSISKRISKVIQVMQNLGIKSDIMDGVDSHAQLERKRELRHTFSSESESNLVGLEKNVEKLVEELVGNDSSHGVSITGLGGLGKTTLARQIFDHDKVKSHFDGLAWVCVSQEFTRKDVWKTILGNLSPKYKDSDLPEDDIQKKLFQLLETKKALIVFDDLWKREDWYRIAPMFPERKAGWKVLLTSRNDAIHPHCVTFKPELLTHDECWKLLQRIAFSKQKTITGYIIDKEMVKMAKEMTKHCKRLPLAVKLLGGLLDAKHTLRQWKLISENIISHIVVGGTSSNENDSSSVNHVLSLSFEGLPGYLKHCLLYLASYPEDHEIEIERLSYVWAAEGITYPGNYEGATIRDVADLYIEELVKRNMVISERDALTSRFEKCQLHDLMREICLLKAKEENFLQIVTDPTSSSSVHSLASSRSRRLVVYNTSIFSGENDMKNSKLRSLLFIPVGYSRFSMGSNFIELPLLRVLDLDGAKFKGGKLPSSIGKLIHLKYLSLYQASVTYLPSSLRNLKSLLYLNLRINSGQLINVPNVFKEMLELRYLSLPWERSSLTKLELGNLLKLETLINFSTKDSSVTDLHRMTKLRTLQILISGEGLHMETLSSALSMLGHLEDLTVTPSENSVQFKHPKLIYRPMLPDVQHFPSHLTTISLVYCFLEEDPMPTLEKLLQLKVVSLWYNAYVGRRMVCTGGGFPPLHRLEIWGLDALEEWIVEEGSMPLLHTLHIVDCKKLKEIPDGLRFISSLKELAIRTNEKVFQKKVSKGGEDYYKMQHVPLIRYNWPQEPENNEVIYSFPSPII
What is the function of this protein?
Potential disease resistance protein.
What are the official names of this protein?
Putative disease resistance protein At1g59780.
What is the protein family that this protein belongs to?
Belongs to the disease resistance NB-LRR family.
Protein: SELA_ACTP7
Sequence: MQKLFRAIPAIDKLIKSPQGVDLIERFGHQAFVQEARALIENAREQIIKQQCLPAFMNEQSAIFSLIEQNLQKKRMVSSKTVFNLTGTVLHTNLGRGLWSENAITAATNAMRNNVALEFDIDEGKRSHRDIYISQLIQQLTGAEAACVVNNNAAAVLLMLATFAQGKEVIVSRGELVEIGGAFRIPDIMAQAGCKLVEVGTTNRTHLWDYRNAINENTAFLMKVHTSNYHVQGFTKSVSEEELVELAKEFDLPVISDLGSGSLTDMAVLGLPAEPMVQQKVAAGVDLVSFSCDKLLGGPQAGIIVGKKVLIDALQSHPLKRVLRCDKVILSALEATLRHYLFPEKLTDEVPTFQLLTQSIETLQNKAERLKAVLNKRLDSRYILQVEPSLAQIGSGSLPTETLASVAVTVFAEKQSDLLELEKRFKALPSPIIGRFAQQKFWLDVRSAAQFEQLLNMLEEA
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EF1A_META3
Sequence: MAKEKPVLNVAFIGHVDAGKSTTVGRLLLDSGTIDPQIIERLKREASEKGKAGFEFAYVMDGLKEERERGVTIDIAHKKFESKKYDVTIVDCPGHRDFIKNMITGASQADAAVLVCDVNDAKTGLQPQTREHIFLIRTLGVNQLAVAINKMDTVDYSEEEYKAMVDMLSNQLLKMLGYNPANIHFVPVASFVGDNNVKKSDKMPWYKGPTLVEVIDTFNPPEKPTNLPLRMPIQDVYTITGVGTVPVGRVETGVMKPGDKVVFEPAGVSGEIKTIEAHHEQLPKAEPGDNVGFNVRGVGKKDIKKGDVLGHPDNIPTVAEEFTAQIVVLQHPSVMTVGYTPVFHAHTAQVACTFMELQKKLNPATGEVKEENPDFLKAGDAAIVKIMPTKPMVIENVKEIPQLGRFAIRDMGMTVAAGMCIDVKAKNK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha, EF-1-alpha, Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_PSELT
Sequence: MRVKKDDLVEVISGKDKGKRGKVLKVLPRENKVVIQGVNIVKRHQRPIPQLREGGIIEREAPIYASKVMLVCPNCDKPTRVGMRFLDDGAKVRFCKKCGEIVDKA
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: AGLF_HALVD
Sequence: MQAVVLAAGKGTRLRPLTEDKPKGMVEVDGKPILTHCFDQLVDLGAEKLVVVVGYKKEIIIQHYDDEYRGVPITYAHQREQKGLAHALLTVEDHIDEDFMLMLGDNIFNANLGDVVKRQREDRADAAFLVEEVDWDEASRYGVCVTNDYGEITEVIEKPEEPPSNLVMTGFYTFTPAIFHACHLVQPSNRGEYEISEAIDLLIRSGRTIDAIRIDGWRLDIGYPEDRDEAEQRLQEETTQATE
What is the function of this protein?
Involved in the assembly of a N-linked pentasaccharide that decorates the S-layer glycoprotein and flagellins.  Involved in the biosynthesis of the hexuronic acid found at position 3 of the pentasaccharide.
What are the official names of this protein?
UTP--glucose-1-phosphate uridylyltransferase AglF, Archaeal glycosylation protein F.
What is the protein family that this protein belongs to?
Belongs to the UDPGP type 2 family.
Protein: ALG10_DEBHA
Sequence: MWNVQVVLTSIFVIFCGIVFRLVALNVKDPFIDEIFHLRQCQTYCALRFDIWDHKITTPPGLYILGMVYAEVVKRITFTSESLVSVCENMNVLRSANLFGGLVVLPLIVQGLVEKEKPQFWTVNIVAMPLLFTYYFLFYTDIWASILIVASLALVVRQPLGLITSSYISGIIAFASLWFRQTNIIWIAFIASLLVDKRRREHHNDMGFVQNGINFIRQAVKDWVAVLPFISNIILFAIFVKYNEGITFGDKENHKLNLHIVQVFYCFTFMSMFTWPVWLSIRLIKRYIHFTILGNYGLNTIFTIGSGILIKFIIDNYTVVHPFLLADNRHYTFYIWKRILNREYSNIFMIPIYHFCTWNIIDSLSHNIGGLTPITIITFIGGIFITIIPSPLFEPRYYIVPLLIYRLYVRPTKEKVFGISISRHALEFFWFMMVDVAITVIFLCYEFTWFSEPGKIQRIVW
What is the function of this protein?
Adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation.  Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol.
What are the official names of this protein?
Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase, Alpha-1,2-glucosyltransferase ALG10-A, Alpha-2-glucosyltransferase ALG10, Asparagine-linked glycosylation protein 10, Dolichyl-phosphoglucose-dependent glucosyltransferase ALG10.
What is the protein family that this protein belongs to?
Belongs to the ALG10 glucosyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PRMA_ANOFW
Sequence: MKWSEISIHTTHEAVEAISNILHEAGAGGVVIEDPFELTKERETTYGEIYQLNPDDYPEEGVIIKAYLPVNSFLGETVEEIKQAINNLMLYNIDIGRNKITISEVNEEEWATAWKKYYNPVKISERFTIVPTWETYEPVSSDELIIELDPGMAFGTGTHPTTVMCIQALEKTVKKGDTVVDVGTGSGILSIAAAMLGAKRVHALDLDPVAVESAKLNVKLNKVHDVVTVSQNNLLDRMDEQADVIVANILAEIILRFVDDAYRLLRSDGVFITSGIIQTKKQEVKEGLLRAGFTIEETLTMEDWVAFIAKKQ
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_ROSCS
Sequence: MSRIADTFARLRAAGRTALMPYLMTGYPERDSVLDLAPALEDAGADLFELGVPFSDPLADGATIQRASERALANGVRLEHCIATIAVLRERGVRAPIVPMGYYNPFLQYGLARLARDMAAAGADGLIIPDLPPEEAQECHAACREYGLDLIFFVAPTTPDERIARITALASGFIYCVSLTGVTGARRELWSGLPAFLERVRRHTTLPLVVGFGISSADHVREVGRHAAGAIVASALINVIEQSHPGEYVARAAEFVRLLRG
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: UVRC_RICRO
Sequence: MTLEITGSELIKSKLIDAPERSGVYRMFDVNKQVLYVGKAKNLKKRLTNYIKSNLDNKTLRMIANTCFLEYSITNSEVEALLLEAQLIKKFQPKFNILLKDCKSFPFIKLRLEHDFPQLLKYRGKTLSDGKFFGPFASSVDVNTTLTELQKIFKLRSCTDNYFNSRTRPCLQYEIKRCYAPCVGKINKEDYRDLVTQVKDFLQGRTKELQENLSRKMEELSSQMRFEEAAEIRDRIKALSYVQLKAGVSDVVKDADIIAIVEKNGHYCVEVFLYRAGQACGNIPYFPTSTENSTKEEVLEYFLLQFYQKQHVPAAIIINHEINDKENVIEAIKKINNILQLNITVPNKGGKAKLVQNAEINALFSLEQYLKKFAKNQEIIFEIKELFGLSAIPERIEIYDNSHIQGKFAVGVMVVAGKVGFDKKEYRVFNVYAPSLVCHSRESGDPKRLMDSCFRGNGIKNCWGDIKGDDYEMLRQVLTRRLTRLRQEPHKLPSLMIIDGGKGHLGVVKEVMDKFEMNIPFVCMSKGVDRNAGFEQFHVIGKEVFTLDKNLPVMKYLQILRDEAHNFAIKNHRLGRSRAIKISRLDDIEGVGETRKKALLHYFGSYKAVCDATIYELAKVNGINKLLAEMIFNVLHRKN
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMD_HAHCH
Sequence: MSRRRKKLPQESITCEIESLSHEGRGVSHKDGKTLFVEGALPGETVTARYVNSRRSYDELAVEEVLTQHPQRIEPDCQFSKLCGGCSMQHVDLGFQINHKESVLLDHLRHFGDLKPEQVVPPLVGAGRGYRTKARLGVRYVAKRDEVLVGFRERYSNFLTAIDECPILIESVGGRIPELKALVRSLSGYQRIPQIEVAAGDDMCALVIRHMDPLTEEDLQKLIAFSEQTGLAIYLQPKGPDTVAKLWPKDGQELLSYQLRDYGLTMQFHPMDFTQVNRDINRRMLAQALEWLQPQAGETILDLFCGLGNFTLPIARSAAHVVGVEGSEDMVRRGYANAELNGISNVEFHAADLHLPLAPAKEAKHAWLRTYDKVLLDPPRSGAEELAKQMTRFGAKRIVYVSCNPATLARDAGILATQGYKLIKAGVMDMFPHTAHVESMALFEKA
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: PERI2_PERAM
Sequence: YPCKLNLKLGKVPFH
What is the function of this protein?
Antimicrobial peptide which displays antifungal activity and antibacterial activity against a wide range of Gram-positive and Gram-negative bacteria (PubMed:27167617, PubMed:28173695, PubMed:28733329, PubMed:30554389).  Has antibacterial activity against the Gram-positive bacteria E. faecium ATCC 19434 (MIC=2. 5 uM), E. faecalis ATCC29212 (MIC=2. 5 uM), S. epidermidis KCTC 1917 (MIC=5 uM), S. mutans KCTC 3065 (MIC=5 uM), and the Gram-negative bacteria E. coli BW25113 (MIC=5 uM), P. aeruginosa ATCC 27853 (MIC=10 uM), S. typhimurium KCTC 1926 (MIC=5 uM) and S. enteritidis ATCC 13076 (MIC=5 uM) (PubMed:30554389).  Has antifungal activity against C. albicans ATCC 90028 (MIC=10 uM), C. parapsilosis ATCC 22019 (MIC=5 uM), T. beigelii KCTC 7707 (MIC=5 uM), M. furfur KCTC 7744 (MIC=5 uM), A. flavus KCTC 6905 (MIC=10 uM) and A. fumigatus KCTC 6145 (MIC=10 uM) (PubMed:28733329).  Likely to exert its antifungal and antibacterial effects by promoting the generation of reactive oxygen species (ROS) which leads to the induction of apoptotic signaling cascades in the bacterial or fungal cells characterized by membrane depolarization, DNA fragmentation, caspase-like protein activation, and phosphatidylserine externalization (PubMed:28733329, PubMed:30554389).  In E. coli, this ROS generation activates the E. coli SOS caspase RecA which promotes a cell death mechanism analogous to eukaryotic apoptotic cell death (PubMed:30554389).
What are the official names of this protein?
Periplanetasin-2, Peri-2.
Protein: PSAB_MASLA
Sequence: MATKFPKFSQDLAQDPTTRRIWYAMATGNDFESHDGMTEENLYQKIFATHFGHVAIIFLWASSLLFHVAWQGNFEQWIKDPIHIRPIAHAIWDPQFGKPAIEAFTQGGANYPVNISYSGIYHWWYTIGMRTNNDLYMGAVFLLILASVFLFAGWLHLQPKFRPSLSWFKSAEPRLNHHLAGLFGVSSLAWAGHLIHVAIPESRGQHVGWNNFLSTLPHPAGLQPFFTGNWGVYASDPDTANHVFGTSQGAGTAILTFLGGFHPQTESLWLTDMAHHHLAIAVIFIIAGHMYRTNFGIGHSIKEMLNSKAGLVPGTNSEGQFNLPHQGLYDTYNNSLHFQLGIHLAALGTITSLVAQHMYAMPPYAFIAKDYTTQAALYTHHQYIAIFLMLGAFAHGAIFWVRDYDPEQNKGNVLDRVLKHKEAIISHLSWVSLFLGFHTLGLYVHNDVVVAFGTPEKQILIEPVFAQFIQASHGKVLYGLNVLLSNPDSVAYTAYPNYGNVWLQGWLDAINSGTNSLFLTIGPGDFLVHHAFALALHTTVLILVKGALDARGSKLMPDKKDFGYAFPCDGPGRGGTCDISAWDAFYLATFWALNTVGWVTFYWHWKHLGIWQGNVAQFNESSTYLMGWFRDYLWANSAQLINGYNPYGMNNLSVWAWMFLFGHLVWATGFMFLISWRGYWQELIETLVWAHERTPLANLVRWKDKPVALSIVQARLVGLTHFTVGYVLTYAAFLIASTAGKFG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: KAD_CHLCV
Sequence: MVNSIFYIIMGPPGSGKGTQSQRLANHLGLPHISSGDLFRSAIKSATPLGSKAAEYINKGLLVPDNLVWEIVQETLNKPGCKSGCIIDGFPRTLDQAVLLNDFLVKSNAADYRVIQLDVSAEEIISRIHSRFICPACNYVYNQSQGFKECPTCHVALIRRSDDSLEVIHQRLESYEKATVPVINYYEDLGKLIHIPSETSPDEVFQSILACTEA
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_HALMD
Sequence: MNCPDCGNERTRVIDTETSADGTSVRRRRECQRCSFRFTTYERPEWESLQVKKRDGTIESFDRQKLRAGIERAVEKRDVTETTVTALVDDVESELQGREARIVSSSLIGELVSESLRTLDKVAYIRFVSVYKAFSEPQEFLRELDAVLDAELDDFEASNSSQ
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: DC1I2_HUMAN
Sequence: MSDKSELKAELERKKQRLAQIREEKKRKEEERKKKETDQKKEAVAPVQEESDLEKKRREAEALLQSMGLTPESPIVFSEYWVPPPMSPSSKSVSTPSEAGSQDSGDGAVGSRTLHWDTDPSVLQLHSDSDLGRGPIKLGMAKITQVDFPPREIVTYTKETQTPVMAQPKEDEEEDDDVVAPKPPIEPEEEKTLKKDEENDSKAPPHELTEEEKQQILHSEEFLSFFDHSTRIVERALSEQINIFFDYSGRDLEDKEGEIQAGAKLSLNRQFFDERWSKHRVVSCLDWSSQYPELLVASYNNNEDAPHEPDGVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPNLVVGGTYSGQIVLWDNRSNKRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLISISTDGKICSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDLWNLNNDTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIYDVGEQIAVPRNDEWARFGRTLAEINANRADAEEEAATRIPA
What is the function of this protein?
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function (PubMed:31079899).  Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules (PubMed:31079899).  The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCTN1 (By similarity).  Involved in membrane-transport, such as Golgi apparatus, late endosomes and lysosomes (By similarity).
What are the official names of this protein?
Cytoplasmic dynein 1 intermediate chain 2, Cytoplasmic dynein intermediate chain 2, Dynein intermediate chain 2, cytosolic, DH IC-2.
What is the protein family that this protein belongs to?
Belongs to the dynein intermediate chain family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm. Note=Detected in the cytoplasm of pachytene spermatocytes. Localizes to the manchette in elongating spermatids.
Protein: LRGB_BACC7
Sequence: MASTMTPYFGIVVSLIAYGIGTLLFKHSKGFFLFTPLFVAMVLGIVFLKVGNFTFEEYNTGGKMISFFLEPATIAFAIPLYKQVDKLKKYWWQILSAIVVGSICSVIVVFIVAKAIGLDTAVMNSMLPQAATTAIALPISESIGGIPAITSFAVIFNAVIVYALGALFLKTFRVKHPIAKGLALGTAGHALGVAVGIEMGEVEAAMASIAVTVVGVVTVVVIPMFMPFIG
What is the function of this protein?
Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA.  The LrgAB and CidA proteins may affect the proton motive force of the membrane.  May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses.
What are the official names of this protein?
Antiholin-like protein LrgB.
What is the protein family that this protein belongs to?
Belongs to the CidB/LrgB family. LrgB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RSMH_BACFR
Sequence: MKEEETTYHVPVLLKESVDAMNISPDGTYVDVTFGGGGHSREILSRLGDGGRLLGFDQDEDAERNIVNDPHFTFVRSNFRYLHNFLRYHDIGEVDAILADLGVSSHHFDDSERGFSFRFDGKLDMRMNKRAGITAADVVNTYEEERLADIFYLYGELKNSRKLASVIVKARTGQKIETIGEFLEIIKPLFGREREKKELAKVFQALRIEVNQEMEALKEMLMAATEALKPGGRLVVITYHSLEDRMVKNIMKTGNVEGKATQDFFGNLQTPFRLVNNKVIVPDEDEITRNPRSRSAKLRIAEKK
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1507_METJA
Sequence: MGKSMKVDDIITFAFKNIKQKRTQSLLTIIGIVIGVLAMVSLISLGYGVQNYIHEEMMKMGSNKITILPMKQFGVPPSHLFTKKEIKAIKNVKGVDTVMYGWYGGCEIEYNGEKKFVSYYYAIPSKLREVYKDSGYDIEEGRWLEDNDKYACVIGYGTAHNLFDREIKVGDVIKIKDKKFRVVGILKQIGNQQDDNSIILNIDVGEKLFGNEGKYNFISVTVKEGEDIEKVSEEIKKALKKSFGDEDFSVLTAEQLAKTVSSVLGVITIFVVGVAAISLLVGAVGISNTMHMSILERRKDIGILKALGAETTDILAIFVVESGFLGLFGGIVGLVLGILLAEVIEALAHKMGYLMVNAWISWELIVGVLIFSFLVGVISGYFPARSGAKLNPIETLRGE
What are the official names of this protein?
Uncharacterized ABC transporter permease MJ1507.
What is the protein family that this protein belongs to?
Belongs to the ABC-4 integral membrane protein family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TSAE_MYCTO
Sequence: MSREGIRRRPKARAGLTGGGTATLPRVEDTLTLGSRLGEQLCAGDVVVLSGPLGAGKTVLAKGIAMAMDVEGPITSPTFVLARMHRPRRPGTPAMVHVDVYRLLDHNSADLLSELDSLDLDTDLEDAVVVVEWGEGLAERLSQRHLDVRLERVSHSDTRIATWSWGRS
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB.  TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity).
What are the official names of this protein?
tRNA threonylcarbamoyladenosine biosynthesis protein TsaE, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaE.
What is the protein family that this protein belongs to?
Belongs to the TsaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDEL1_CHICK
Sequence: MDSEEIPTFSSPKEETAYWKELSLKYKQSFQEAREELAEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVETLKEKLEHQYAQSYKQVSLLEDDLSQTRAIKDQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDDKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGSENSFPSPKAIPNGFGTSPLTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKSYISGNANSSMMSSNGTKYPHPGHTSFFDKGAVNGFDQGTPGLGASRPSSAPGMLPLSV
What is the function of this protein?
Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome.  Positively regulates the activity of the minus-end directed microtubule motor protein dynein.  May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end.  Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts.
What are the official names of this protein?
Nuclear distribution protein nudE-like 1.
What is the protein family that this protein belongs to?
Belongs to the nudE family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Localizes to the interphase centrosome and the mitotic spindle.
Protein: NTPPA_POLSJ
Sequence: MPAADFVYLASQSPRRAQLLEQLGVRYQRLAPAPDEDTEALEAVLGKESPVAYVKRVTRLKLDAASERAKRQGLAPAPILCSDTTVALGRSILGKPANAAEATRMLRQLSGATHRVLTAVAVQQGRRRIEALSISRVTFAPMTAAQISSYVASGEPMGKAGAYAVQGRVAMYISHISGSYSGIMGLPLHETAWLLRAAGLKI
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPK3_KARBI
Sequence: DPPFSPRL
What is the function of this protein?
Myoactive.
What are the official names of this protein?
Pyrokinin-3, PK-3, FXPRL-amide.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.