PharMolix/UniProtQA huggingface dataset:
Protein: MYOB1_ARATH
Sequence: MGSRSFTRALALAFNEWLLMFMLFVNSIFSYVIARFADYSELQSPCLMCSNLDHILRRTKDLKKTHWDIICSKHKSEISSLVYCHAHGKLVDVRGMCETCLFSFATTNKSNAETYRLLVGKLGEDSHFGSKSDRSKYPNCSKLTDCTCCNQLWTPQTAATQVAEREILPKIGLLGKIRTGKQSAPKKSVSFNHLPDVGYTELKIHSDTESEAVFSDTEPKQESSLNHLPPVGYNEPKIGLVGDVRTGKPSTPKKSVSFNHLPDVGYTELKIHSDTESEAVFSEDECVVLKDEDHKYQIVDLQTHPIITLPYDLATDKLLNFDFPLEPFVTRNDREEVQLQETNWRTYSSFPVLIPVNDVPETSEKVFKEEEINSLDNLFLTSRAMKHFAAAKVKEEPIRLQDISSTPDVKENPANASLMEETELICLSDVTATSGAMEHSEVILKEREELIHLQDISVTPDFKENPANASLLEETELICLNDVTSPLRAVEHSAVLLKDKVEPIRLQDGGSLTPDFMENSANASILEETELICVNDVTSTSRTMGHSSVVLKENEEPIRFQDSSLTPDFKENPASTFLVEETELICLNDVTSPSRAMEHSTVFIEEKEELVRHQNITLTQDFMENPANSSLREETELICLNDVTSTSEVAETPEDVLEGIELMSIHDISLDEVSESVTTNQTSVEISKERDTDQADITSLESEYIVVPSPNSMPENSTDNCVSDKKEMKETSLRISSLSEMAPRDVTSHTEAALESESSSFNSMSVAAETNQYSGELLDLADAYNIVVGNEGHYDSNGRQQIENWMKKDTSRVSEDLKALLTQISASRGIEFLSPRDVSPKISVNSSDQETKNLDHDMQLLLQKRMLERNESNLSLEGVSVTEIEGESEGDRLKRQVDYDRKLLTGLYKELEEERSASAVATNQAMAMITRLQEEKASFQMEALQNLRMMEEQAEYDMEAIQRLNDLLVEREKLIQDLEAEIEYFRDQTPQKKNKLDVAEKVTEMDSPSEGMSNKIQSCLVGFDEERLYITSCLEKIENRVNGKAHDDNLPAQESVSELHERVERLKGDLYFLEQVMNSLGHGNEGVQFVKEIASHLQTLRSLSMKRQDQTEC
What is the function of this protein?
Membrane-anchored myosin receptors that define a distinct, plant-specific transport vesicle compartment.
What are the official names of this protein?
Myosin-binding protein 1.
What are the subcellular locations of this protein?
Endomembrane system; Single-pass membrane protein.
Protein: SYR_STRP1
Sequence: MDTKTLIASEIAKVVPELEQDAIFNLLETPKNSDMGDLAFPAFSLAKVLRKAPQMIASELAEQIDESQFEKVVAVGPYINFFLDKAKISSQVLEQVITAGSDYAQQDEGQGRNVAIDMSSPNIAKPFSIGHLRSTVIGDSLAHIFAKMGYKPVKINHLGDWGKQFGMLIVAYKKWGDEAAVQAHPIDELLKLYVRINAEAETDPTVDEEAREWFRKLEDGDKEATELWQWFRDESLLEFNRLYDQLHVTFDSYNGEAFYNDKMDEVLDLLEAKNLLVESKGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKRTYDFAKSVYVVGNEQAAHFKQLKAVLKEMGYDWSDDMTHVAFGLVTKGGAKLSTRKGNVILLEPTVAEAINRAASQIEAKNPNLADKEAVAHAVGVGAIKFYDLKTDRMNGYDFDLEAMVSFEGETGPYVQYAHARIQSILRKADFTPSATTTYSLADAESWEIIKLIQDFPRIIKRTSDNFEPSIMAKFAINLAQSFNKYYAHTRILDDNSERDNRLALCYATATVLKEALRLLGVDAPNEM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_PARMW
Sequence: MSDSTASSINKGLAAADPAIAALIEKEQQRQETHLELIASENFASRAVMDAQGSVLTNKYAEGLPSKRYYGGCEHVDAIEELAIERAKELFGAAWANVQPHSGAQANFAVFLALLQPGDTIMGLDLSHGGHLTHGSPVNVSGKWFNVVQYGVDRETQRLDMEAIRQLALEHKPKLIVCGFSAYPRTIDFAAFRAIADEVGAFLLADMAHIAGLVAAGVHPSPVPHCDVVTTTTHKTLRGPRGGLILCRDADFAKKFDKAVFPGSQGGPLEHVIAAKAVAFGEALQPAFKTYSQHVVANAAALAERLIARGIDVVSGGTDNHVVLLDLRSVGMTGKVADLLVSDVHITANKNTVPFDPESPFVTSGLRLGTAALTTRGFDAGAFREVADVIADRLLNPEDDAVQQQCLRRVEALCQRFPLYAAARQPALA
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IHFA_METPB
Sequence: MAGKTVTRADLSEAVYQQVGLSRAESAALVETVLGEICNCLSSGETVKLSSFGSFVVRSKGKRIGRNPKTGVEVEIEPRQVMVFKPSNVLKARINGGHVNGLDADEDE
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: EF1B_HALMA
Sequence: MGKVAAKIKVMPESPEVDLDDLQERLEGVLPEGTKINGFEREDVAFGLVALTPTVIVPDDTGGTEAVEEAFANVDDVESVSIESTGRL
What is the function of this protein?
Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
What are the official names of this protein?
Elongation factor 1-beta, EF-1-beta, aEF-1beta.
What is the protein family that this protein belongs to?
Belongs to the EF-1-beta/EF-1-delta family.
Protein: RM15_HUMAN
Sequence: MAGPLQGGGARALDLLRGLPRVSLANLKPNPGSKKPERRPRGRRRGRKCGRGHKGERQRGTRPRLGFEGGQTPFYIRIPKYGFNEGHSFRRQYKPLSLNRLQYLIDLGRVDPSQPIDLTQLVNGRGVTIQPLKRDYGVQLVEEGADTFTAKVNIEVQLASELAIAAIEKNGGVVTTAFYDPRSLDIVCKPVPFFLRGQPIPKRMLPPEELVPYYTDAKNRGYLADPAKFPEARLELARKYGYILPDITKDELFKMLCTRKDPRQIFFGLAPGWVVNMADKKILKPTDENLLKYYTS
What are the official names of this protein?
39S ribosomal protein L15, mitochondrial, L15mt, MRP-L15, Mitochondrial large ribosomal subunit protein uL15m.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: PAPP2_HUMAN
Sequence: MMCLKILRISLAILAGWALCSANSELGWTRKKSLVEREHLNQVLLEGERCWLGAKVRRPRASPQHHLFGVYPSRAGNYLRPYPVGEQEIHHTGRSKPDTEGNAVSLVPPDLTENPAGLRGAVEEPAAPWVGDSPIGQSELLGDDDAYLGNQRSKESLGEAGIQKGSAMAATTTTAIFTTLNEPKPETQRRGWAKSRQRRQVWKRRAEDGQGDSGISSHFQPWPKHSLKHRVKKSPPEESNQNGGEGSYREAETFNSQVGLPILYFSGRRERLLLRPEVLAEIPREAFTVEAWVKPEGGQNNPAIIAGVFDNCSHTVSDKGWALGIRSGKDKGKRDARFFFSLCTDRVKKATILISHSRYQPGTWTHVAATYDGRHMALYVDGTQVASSLDQSGPLNSPFMASCRSLLLGGDSSEDGHYFRGHLGTLVFWSTALPQSHFQHSSQHSSGEEEATDLVLTASFEPVNTEWVPFRDEKYPRLEVLQGFEPEPEILSPLQPPLCGQTVCDNVELISQYNGYWPLRGEKVIRYQVVNICDDEGLNPIVSEEQIRLQHEALNEAFSRYNISWQLSVHQVHNSTLRHRVVLVNCEPSKIGNDHCDPECEHPLTGYDGGDCRLQGRCYSWNRRDGLCHVECNNMLNDFDDGDCCDPQVADVRKTCFDPDSPKRAYMSVKELKEALQLNSTHFLNIYFASSVREDLAGAATWPWDKDAVTHLGGIVLSPAYYGMPGHTDTMIHEVGHVLGLYHVFKGVSERESCNDPCKETVPSMETGDLCADTAPTPKSELCREPEPTSDTCGFTRFPGAPFTNYMSYTDDNCTDNFTPNQVARMHCYLDLVYQQWTESRKPTPIPIPPMVIGQTNKSLTIHWLPPISGVVYDRASGSLCGACTEDGTFRQYVHTASSRRVCDSSGYWTPEEAVGPPDVDQPCEPSLQAWSPEVHLYHMNMTVPCPTEGCSLELLFQHPVQADTLTLWVTSFFMESSQVLFDTEILLENKESVHLGPLDTFCDIPLTIKLHVDGKVSGVKVYTFDERIEIDAALLTSQPHSPLCSGCRPVRYQVLRDPPFASGLPVVVTHSHRKFTDVEVTPGQMYQYQVLAEAGGELGEASPPLNHIHGAPYCGDGKVSERLGEECDDGDLVSGDGCSKVCELEEGFNCVGEPSLCYMYEGDGICEPFERKTSIVDCGIYTPKGYLDQWATRAYSSHEDKKKCPVSLVTGEPHSLICTSYHPDLPNHRPLTGWFPCVASENETQDDRSEQPEGSLKKEDEVWLKVCFNRPGEARAIFIFLTTDGLVPGEHQQPTVTLYLTDVRGSNHSLGTYGLSCQHNPLIINVTHHQNVLFHHTTSVLLNFSSPRVGISAVALRTSSRIGLSAPSNCISEDEGQNHQGQSCIHRPCGKQDSCPSLLLDHADVVNCTSIGPGLMKCAITCQRGFALQASSGQYIRPMQKEILLTCSSGHWDQNVSCLPVDCGVPDPSLVNYANFSCSEGTKFLKRCSISCVPPAKLQGLSPWLTCLEDGLWSLPEVYCKLECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEGGIWEQGSCIPVVCEPPPPVFEGMYECTNGFSLDSQCVLNCNQEREKLPILCTKEGLWTQEFKLCENLQGECPPPPSELNSVEYKCEQGYGIGAVCSPLCVIPPSDPVMLPENITADTLEHWMEPVKVQSIVCTGRRQWHPDPVLVHCIQSCEPFQADGWCDTINNRAYCHYDGGDCCSSTLSSKKVIPFAADCDLDECTCRDPKAEENQ
What is the function of this protein?
Metalloproteinase which specifically cleaves insulin-like growth factor binding protein (IGFBP)-5 at the '163-Ser-|-Lys-164' bond.  Shows limited proteolysis toward IGFBP-3.
What are the official names of this protein?
Pappalysin-2, Pregnancy-associated plasma protein A2, PAPP-A2, Pregnancy-associated plasma protein E1, PAPP-E.
What is the protein family that this protein belongs to?
Belongs to the peptidase M43B family.
What are the subcellular locations of this protein?
Secreted.
Protein: REPS_STRPY
Sequence: MNIPFVVETVLHDGLLKYKFKNSKIRSITTKPGKSKGAIFAYRSKKSMIGGRGVVLTSEEAIHENQDTFTHWTPNVYRYGTYADENRSYTKGHSENNLRQINTFFIDFDIHTEKETISASDILTTAIDLGFMPTLIIKSDKGYQAYFVLETPVYVTSKSEFKSVKAAKIISQNIREYFGKSLPVDLTCNHFGIARIPRTDNVEFFDPNYRYSFKEWQDWSFKQTDNKGFTRSSLMVLSGTEGKKQVDEPWFNLLLHETKFSGEKGLVGRNSVMFTLSLAYFSSGYSIETCEYNMFEFNNRLDQPLEEKEVIKLVRSAYSENYQGANREYITILCKAWVSSDLTSKDLFVRQGWFKFKKKRSERQRVHLSEWKEDLMAYISEKSDVYKPYLVTTKKEIREALGIPERTLDKLLKVLKANQEIFFKIKSGRNGGIQLASGKSLLLSIIKVKKEEKESYIKALTNSFDLEHTFIQETLNKLAERPKTDTQLDLFSYDTG
What is the function of this protein?
Essential for replication.
What are the official names of this protein?
Protein RepS.
Protein: Y1679_CLOAB
Sequence: MGSEINDNTIEFDVLKNKEDLTKEILNEVYNSLKEKGYNPINQLVGYLISGDPTYITNYNGARALVRKLERDEILEEVLKSYLGIK
What are the official names of this protein?
UPF0297 protein CA_C1679.
What is the protein family that this protein belongs to?
Belongs to the UPF0297 family.
Protein: GLNQ_GEOSE
Sequence: MIYFHQVNKYYGDFHVLKDINLTIHQGEVVVIIGPSGSGKSTLVRCINRLETISSGELIVDNVKVNDKHIDINQLRRNIGMVFQHFNLYPHMTVLQNITLAPMKVLRIPEKEAKETAMYYLEKVGIPDKANAYPSELSGGQQQRVAIARGLAMKPKIMLFDEPTSALDPETIGEVLDVMKQLAKEGMTMVVVTHEMGFAREVADRIVFMDQGRILEEAPPEEFFSNPKEERAKVFLSRILNH
What is the function of this protein?
Part of the binding-protein-dependent transport system for glutamine.  Probably responsible for energy coupling to the transport system.
What are the official names of this protein?
Glutamine transport ATP-binding protein GlnQ.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL25_HAEIN
Sequence: MAFKFNAEVRTAQGKGASRRLRHNGQIPAIVYGGSEEPVSIILNHDELNNAQAHESFYSEVITLVVEGKEVAVKVQAMQRHPFKPKLVHIDFKRA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: ACMB_GORST
Sequence: MTSTFSSLDVSAFTSAADRILAEAVTGDARVPGVVAMVTDRDRTVYSGAAGQRSLGGSAPMTTDDVFAIFSTTKAITATAALQLVEEGLLDLDAPASTYAPAIGTLQVIEGFDDAGEPILRAPKSVPTTRQLLTHTGGFGYDFFDEIYNRLAEEKGQPSVTTASRAALMTPLLFDPGERWQYGTNIDWVGQVVEGLRGKRLGEVFAERIFAPLGIENMSFILREDFRSHLTEIHARNADGSLTPMGLELPSPPEVDFGGHGLYGTVGEYMKFIRMWLNDGVGEGGRVLKAETVEMALRNHLGDLPVTMLPGVIPSLSNDAEFFPGQSKSWSLPFMINNETAPTGRPAGAQGWAGLANLFYWIDRQNGYGGYWATQILPFGDPTSFTKYMEFETAFYDALKS
What is the function of this protein?
Plays an important role in the metabolism of acetone derived from propane oxidation (PubMed:17071761).  Catalyzes the hydrolysis of methyl acetate to acetate and methanol (PubMed:17071761).
What are the official names of this protein?
Methyl acetate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the class-A beta-lactamase family.
Protein: FSA_SALPA
Sequence: MELYLDTANVAEVERLARIFPIAGVTTNPSIVAASKESIWDVLPRLQNAIGEEGTLFAQTMSRDAKGMVEEAKRLNNAIPGIVVKIPVTAEGLAAIKLLKKEGIVTLGTAVYSASQGLLAALAGAKYVAPYVNRVDAQGGDGIRMVQELQTLLEHHAPDSMVLAASFKTPRQALDCLLAGCQAITLPLDVAQQMLNTPAVESAIEKFEQDWKNAFGNLNL
What is the function of this protein?
Catalyzes the reversible formation of fructose 6-phosphate from dihydroxyacetone and D-glyceraldehyde 3-phosphate via an aldolization reaction.
What are the official names of this protein?
Fructose-6-phosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_STRA3
Sequence: MTKLLFMGTPDFSATVLKGILADGKYDVLAVVTQPDRAVGRKKEIKMTPVKEVALENNIPVYQPEKLSGSPELEQLMTLGADGIVTAAFGQFLPTKLLESVGFAINVHASLLPKYRGGAPIHYAIINGEKEAGVTIMEMVAKMDAGDMVSKASVEITDEDNVGTMFDRLAVVGRDLLLDTLPGYLSGDIKPIPQNEEEVSFSPNISPDEERIDWNKSSRDIFNHVRGMYPWPVAHTLLEGNRFKLYEVTMSEGKGSPGQVIAKTKNSLTVATGDGAIELKSVQPAGKPRMDIKDFLNGVGRNLEIGDKFGE
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: ARGB_THEPX
Sequence: MIRRQKYGDEIAKAQVLIEALPYIKKFSGTTVVIKYGGSAMLDCNLKRMVMQDIVLMKFVGLNPIVVHGGGPEINKMLERLGIESKFVNGLRVTDEATMEIVEMVLTGRINKEIVSLINELGGQAIGVSGKDGRLLKAEKDTSNGDIGYVGKIVDVNIDVITMMLEKGYIPVIAPTSFGDDGKTYNVNADTAAGKIAEALKAEKLILLTDVEGILSNINDKSSLISRMDLEHAKEFMNSGRINGGMIPKLECCIKAVENGVKRAHIIDGRLTHSLLLEIFTDEGIGTMIGKECFDDDNL
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURB_IDILO
Sequence: MIELAERHSFKLPAQCRALIELKSSDDVEQLAFEEPYYLLGEGSNTLFVDDFYGTVICNRLLGVCIEEQESSYLITAAAGENWHNFVADLRARSIDGLENLALVPGSVGAAPVQNVGAYGVEVSTFIEQVTAWDIKEKCWVSMNKEACQFAYRDSVFKQHPGRWLITSVVFRLPKDWQPVTHYAPLNQLQGHVSAQKIFDTVVEVRQKKLPDPKVIPNAGSFFKNPVINKAQLDGLLQKWPDMVYFPVADNHVKVAAGWLIEHLGLKSAFVGDAAVNPHQALVLINKAQATGSDITQLALKIMKQVADASGIMLEPEVRLVGQHGLVQLAVEK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH014_HUMAN
Sequence: MGQSLQEGRKQGRLLPAPSAHFLKHAHLASPSEVGGEPEIGSLCASHVLHMSPLYSVNLQVSPGSLTFHSLSLRSTSTRLQPQSTYIVGPLC
What are the official names of this protein?
Putative uncharacterized protein encoded by LINC00208.
Protein: LIPB_HAEIG
Sequence: MNNSLIVRQLGLQDYQEIWHKMQDFTDTRNAETQDEIWLVQHYPVFTQGQAGKPEHLLQRSEIPVVQSDRGGQITYHAPGQQVMYVLIDIKRHKNLNVRQLVTALEQTVVKTLAEYGIESYPKPDAPGVYVDGKKICSLGLRIRRGCSFHGLALNINMDLNPFHYINPCGYAGLEMCQLADFVNQDEADWDNVSAKLIKHFADLLGYNITTL
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOLB_CHLCV
Sequence: MLRRIFVSTFLVFGIVSLYAKDLEVSVRSEISLLPIHVELKIGPNDAKQQKYLRSLCNTFISDLALGDRLQPSSVKSEALSPPFSIAIVSRYPEIAFTIARGSQNHQQFHSLVLTEDISSNRQKIHEAADKIHYALTKVPGISSGKIVFSLSKNPQDGELKQGELWSVDYDGANLRALTQENSLSITPNWMNIGNCNPYLYVSYKYGIPKIFLGSLENTTGKKVLNLQGNQFMPTFSPRKKLLAFISDTYGNPDLFLQSFSLSKGVMGKPRRVLNETFGTQGNPSFSPDGSKLVFVSNRDGRPRLYIIQIDPEIQTPRLLTKKYRNSSCPSWSPDGKKIAFCSVIKGVRQICLYDLSTGKDYQLTTTPIDKEGPSWAIDSQHLVYSAGNSGESELYLLSLITQKTKKIVIGLGEKRFPSWGGFPNNQ
What are the official names of this protein?
Protein TolB homolog.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: SYR2_BACHK
Sequence: MNSLEQVKGLIKEEIQAAVLKAELATEEQIPNVVLESPKDKTNGDFSTNMAMQLARVAKKAPRMIAEELVANFDKAKASIEKIEIAGPGFINFYMDNSYLTDLIPTIVNAGEAYGETNTGKGEKVQVEFVSANPTGDLHLGHARGAAVGDTLCNLLAKAGYDVSREYYINDAGNQIHNLALSVEARYMQALGLEKEMPEDGYHGADIIGIGKSLAEEFGDRYAKADEKESYEFYREYGLKYELAKLQKDLESFRVKFDVWFSETSLYKNGKIDQALAVLKERDEIFEEDGATWFRSMTYGDDKNRVLIKNDGSYTYLTPDIAYHRDKLERGFDKLINIWGADHHGYIPRMKAAIQALGYDKETLEVEIIQMVQLYQNGEKMKMSKRTGKAVTLRELMEEVGVDAMRYFFAMRSGDSHLDFDMDLAVSKSNENPVYYAQYAHARVCSILRQGEELGLATGGDVNYKLVTSEKEVELLKKLGEFPAVVADAAQKRLPHRITNYAFELAATLHSFYNAEKVLNQDNLELSKARYELMKAVRTTLQNALAIVGVSAPEKM
What are the official names of this protein?
Arginine--tRNA ligase 2, Arginyl-tRNA synthetase 2, ArgRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIG_ECOBW
Sequence: MNAEKSPVNHNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLRLGYIAERAGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTLNRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLGWVDQTSLKERHITGLHYNPITNTFKLGPGVDVNYMLHTQNK
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-octaprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone-8 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: B2L14_MOUSE
Sequence: MCSTSVYDLEDIPLEDDDPNSIEFKILAFYARHHVFKNTPAVFSPKLSRTRSLSQKALGTWSTDSWTQVSLPCRGSPSSEKNISLGKKKSSWRTLFRVAEKEEGLPSSPKEIRAQGPQGPFPVERQSGFHNQHWPRSLSSVEQRLESEVVDSKVACIANRVAEIVYSWPPPDVIHSQGGSKLKERVSEILYFRFEGPCDSKNKDGEDQIISKIVELLKFSGDQLGREIKKDKALMSSFQDGLSYSTFKTITDLFLRDVDTRGESEVKARGFKAALAIDAIAKLTAIDNHPMNRMLGFGTKYLREYFSPWVQQNGGWEKILGISHEEVD
What is the function of this protein?
Plays a role in apoptosis.
What are the official names of this protein?
Apoptosis facilitator Bcl-2-like protein 14, Bcl2-L-14.
What is the protein family that this protein belongs to?
Belongs to the Bcl-2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_RICTY
Sequence: MNILNNNLYGMDKEIYEIIKNEKLRQNNVIELIASENFVSSAVLEAQGSILTNKYAEGYPSKRFYNGCDEVDKAEVLAIERAKKLFNCKYANVQPHSGSQANQAVYLALLQPCDTILGMSLDSGGHLTHGAAPNISGKWFNTVAYNVDKETYLIDYDEIKRLAVLHNPKLLIAGFSAYPRKIDFARFREIADKVGAYLMADIAHIAGLVATGEHQSPIPYAHVVTSTTHKTLRGPRGGLILSDYEEIGKKINSALFPGLQGGPLMHVIAAKAVAFLENLQPEYKCYIKQVISNAKALAISLQERGYDILTGGTDNHIVLVDLRKDGITGKCAANSLDRAGITCNKNAIPFDTTSPFVTSGIRFGTSACTTKGFKEKDFVLIGHMVAEILDGLKNNEDNSKTEQKVLSEVKKLIKLFPFYD
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIEN1_HUMAN
Sequence: MSGEPGQTSVAPPPEEVEPGSGVRIVVEYCEPCGFEATYLELASAVKEQYPGIEIESRLGGTGAFEIEINGQLVFSKLENGGFPYEKDLIEAIRRASNGETLEKITNSRPPCVIL
What is the function of this protein?
Increases cell migration by inducing filopodia formation at the leading edge of migrating cells.  Plays a role in regulation of apoptosis, possibly through control of CASP3.  May be involved in a redox-related process.
What are the official names of this protein?
Migration and invasion enhancer 1, HBV X-transactivated gene 4 protein, HBV XAg-transactivated protein 4, Protein C35.
What is the protein family that this protein belongs to?
Belongs to the SelWTH family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell membrane; Lipid-anchor; Cytoplasmic side. Note=Concentrates at the leading edge of migrating cells. Localizes outside membrane raft regions.
Protein: PROA_JANSC
Sequence: MKDLTDNVPALMAEIGARAKNASAELAFASPEAKFTALTAAADAVWARRADIIAANEKDMAFGREKGLSDAMLDRLMLDEARVEGIVTGLRAVAGQEDPVGHVMTEWEMESGLHIKRVRTPLGVIGVIYESRPNVTADAGALCLKSGNAVILRGGSESFHSSGALADCLQEGLRTAGLPEDAVQRVPTRDRAAVSEMLAMTETIDVIVPRGGKGLVALVQREARVPVFAHLEGICHIYLDASADPEKALRVVLNAKTRRTGICGSAECLLIHQDIADTIGQGVVRALIDAGVEVRGDKSIEEIEGVTRASESDWGQEFLDMIIAARVVEDLDDALDHIRTYGSNHTDAIIAEDDAAVARFFQRLDSAILIHNASTQFADGGEFGMGAEIGIATGKMHARGPVGSEQLTSFKYLVTGDGTIRG
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFB_NOSCE
Sequence: MPTISVKKREIEKLLGKSYDSETFSDILFNYGLEIDECIEESDDITYKIEIPANRYDLLCAEGLNYALQSYLFGKVFEDINLQSSEYTIFKQHFGNRSCVAAAIIKNYKFDKYSYDSFISYQEKLCGNLGRNRSLVSMGTHDLDTISWPVTYKSIKKTELKFAPLNCTKEINDLEMHFKDDKNIGKYLQYVDNDNYIVFMDAKGHILSVPPVINSNRTKISVNTTNILVEVTGTNTYKVNTCLKMILSAFRTDNMCQVNIISDKQEILEIKDKSYLLSIDEVYKELNINISVIDLSDLLIKMMYKTNIIDDKHLNVTVPSVRQDVLHKADLIEDIAICYGFNNINMVMPDINTIGSENRLNKFSDKLRLEMCMLGFTEVYTMVLVSKSDNIFGDNSAVVSNYKSLECEAVRSSLYPGLMKAVSSNLHCKIPIKIFEVGDVVFLDSESDVGARNRRYLSCLYVGNKSHLEDVQGPMTVILEKCGIKDYKFERMDDEKKYLKNQSA
What are the official names of this protein?
Probable phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KGUA_SHIFL
Sequence: MAQGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSVSHTTRQPRPGEVHGEHYFFVNHDEFKEMISRDAFLEHAEVFGNYYGTSREAIEQVLATGVDVFLDIDWQGAQQIRQKMPHARSIFILPPSKIELDRRLRGRGQDSEEVIAKRMAQAVAEMSHYAEYDYLIVNDDFDTALTDLKTIIRAERLRMSRQKQRHDALISKLLAD
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRIO_MUSPF
Sequence: MVKSHIGSWLLVLFVATWSDIGFCKKRPKPGGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGGWGQGGGSHGQWGKPSKPKTNMKHVAGAAAAGAVVGGLGGYMLGSAMSRPLIHFGNDYEDRYYRENMYRYPNQVYYKPVDQYSNQNNLVHDCVNITVKQHTVTTTTKGENFTETDMKIMERVVEQMCVTQYQQESEAYYQRGASAILFSPPPVILLISLLILLIVG
What is the function of this protein?
Its primary physiological function is unclear.  Has cytoprotective activity against internal or environmental stresses.  May play a role in neuronal development and synaptic plasticity.  May be required for neuronal myelin sheath maintenance.  May play a role in iron uptake and iron homeostasis.  Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).  Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts.  Also provides Cu(2+) or Zn(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains (By similarity).
What are the official names of this protein?
Major prion protein, PrP, PrP27-30, PrP33-35C.
What is the protein family that this protein belongs to?
Belongs to the prion family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Golgi apparatus. Note=Targeted to lipid rafts via association with the heparan sulfate chains of GPC1. Colocates, in the presence of Cu(2+), to vesicles in para- and perinuclear regions, where both proteins undergo internalization. Heparin displaces PRNP from lipid rafts and promotes endocytosis.
Protein: ACKA_SHESR
Sequence: MSNKLVLVLNCGSSSLKFAVIDAQTGDDQISGLAECFGLEDSRIKWKINGEKHESSLGAFTAHREAVEFIVNKILAGQPELAAQIQAVGHRIVHGGEKFTRSVIIDEHVIKGIEECSSLAPLHNPAHLIGIRAAIASFPKLPQVAVFDTAFHQSMPERAFIYALPYKLYREHGIRRYGMHGTSHLFVSREAAKVLNKPLEETNVICAHLGNGASVTAVKGGKSVDTSMGLTPLEGLVMGTRCGDLDPSIIYHLVHQLGYTLEEVNNLMNKQSGLLGISELTNDCRGIEEGYADGHKGATLALEIFCYRLAKYIASYTVPLGRLDAVVFTGGIGENSDIIREKVLNMLQIFNFHVDSERNKAARFGKKGIITTDNSTVAMVIPTNEEWVIAEDSIKLITK
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.