PharMolix/UniProtQA huggingface dataset:
Protein: HIS4_DELAS
Sequence: MLLIPAIDLKDGHCVRLIQGDMDQSTTFGEDPAIIARRWLDAGARRLHLVDLNGAFAGQPKNLVAIKAILKEVDGRIPVQLGGGIRDLDTIEKYIDAGISYVIIGTAAVKNPGFLQDACSAFGGHVIVGLDAKDGKVAIDGWSKLTGQDVHSVAKRFEDWGVESIIYTDIGRDGMLTGINIDATVNLAQSLKIPVIASGGLAGMADIEALCKVEDEGIEGVICGRAIYSGDLDFAAAQARADELRA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_ECOL6
Sequence: MARIAGINIPDHKHAVIALTSIYGVGKTRSKAILAAAGIAEDVKISELSEGQIDTLRDEVAKFVVEGDLRREISMSIKRLMDLGCYRGLRHRRGLPVRGQRTKTNARTRKGPRKPIKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the E. coli 70S ribosome in the initiation state it has been modeled to contact the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; bridge B1a is broken in the model with bound EF-G, while the protein-protein contacts between S13 and L5 in B1b change.  Contacts the tRNAs in the A and P sites (By similarity).
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: MURD_MOOTA
Sequence: MSWQGKSVLVVGLGRSGRAAATELARLGAKVTACDRQALAEEELENLRKEGVHLILGGYPEVNELQPDLVITSPGVPSGEPPLARARARGIPVWSELELAYRLLPPGVKVVAITGTNGKTTTTSLCGRILQEAGWPAVVGGNIGIPLVKELQEIAPGSYVVCEVSSFQLEAITSFHPQVAAILNITPDHLDRHGSLENYIAAKARVMAYQEARDFAILNYDDPHTRSLAGGARSRVLFFSRRERPPLGAWLEDGVICCDLGAGGTVKLCHCEELSLKGSHNLENSMAAALVALALGVDPEQLTRTLKTFPAVPHRLEPVAEINGVCYINDSKGTNPEATMKAINAYSNPLVLIAGGRNKGSDFTLLAQQMAGRVKHLVLVGEAARELEQAARKAGIDSIYLAPDFASAVREAAGAARPGDIVMLSPACASWDMFKNYEERGDVFKSLVLQMKDDG
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRXB_RICPR
Sequence: MKITTKVLIIGSGPAGLSAAIYTARSALKPILINGMQPGGQLTMTTDVENYPGFAETIQGPWLMEQMSMQAKNVGTEIISDYVERVDLSKRPFKIFTGTGNEYEADSIIICTGAESKWLGIASEQEFRGFGVSSCAICDGFFFKNQEIVVVGGGNSALEEALYLTNHANKVTVVHRRNSFRAEKILQDRLFKNPKISVIWDHIIDEIVGSNKPKAVTGVKIQNVYTNEINLVNCSGVFIAIGHAPNTALFKGQIAIDDDNYIVTQSGSTRTNVEGVFAAGDVQDKIYRQAVTAAASGCMAALEVAKFLNK
What are the official names of this protein?
Thioredoxin reductase, TRXR.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_ECO24
Sequence: MTAIAPVITIDGPSGAGKGTLCKAMAEALQWHLLDSGAIYRVLALAALHHHVDVASEDALVPLASHLDVRFVSTNGNLEVILEGEDVSGEIRTQEVANAASQVAAFPRVREALLRRQRAFRELPGLIADGRDMGTVVFPDAPVKIFLDASSEERAHRRMLQLQEKGFSVNFERLLAEIKERDDRDRNRAVAPLVPAADALVLDSTTLSIEQVIEKALQYARQKLALA
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSK_STAAW
Sequence: MAQKPVDNITQIIGGTPVVKLRNVVDDNAADVYVKLEYQNPGGSVKDRIALAMIEKAEREGKIKPGDTIVEPTSGNTGIGLAFVCAAKGYKAVFTMPETMSQERRNLLKAYGAELVLTPGSEAMKGAIKKAKELKEEHGYFEPQQFENPANPEVHELTTGPELLQQFEGKTIDAFLAGVGTGGTLSGVGKVLKKEYPNIEIVAIEPEASPVLSGGEPGPHKLQGLGAGFIPGTLNTEIYDSIIKVGNDTAMEMSRRVAKEEGILAGISSGAAIYAAIQKAKELGKGKTVVTVLPSNGERYLSTPLYSFDD
What are the official names of this protein?
Cysteine synthase, CSase, O-acetylserine (thiol)-lyase, OAS-TL, O-acetylserine sulfhydrylase.
What is the protein family that this protein belongs to?
Belongs to the cysteine synthase/cystathionine beta-synthase family.
Protein: MUTS_RUEST
Sequence: MSVTPMMAQYLEIKAQYPDALLFYRMGDFYEMFFEDAVNAAEALDIALTKRGKHEGEDIPMCGVPVHAAEGYLLTLIRKGFRVAVGEQLESPAEAKKRGSKSVVKRDVVRLVTPGTLTEDSLLEARRHNFLVAYSELRDQAALAWADISTGAFHVMPVARVRLSPELARLAPSELIVADGPIFDATLPLAEEYKIPLTPLGKASFDSTAAEKRLCHLFNVSALDGFGTFNRAEISAMGAVVDYLEITQKGKLPLLQPPLQESEDRTVQIDASTRRNLELTRSLSGGRAGSLLSVVDRTVTPGGARLLEQRLSSPSRNLDVISARLEALDTIVEDPIRCDTLRGLLRKTPDIDRALSRLALDRGGPRDLAAIRNALSQGEDIERALQDPDLPTLLRDAAHSLEGFQDLLSLLDAALIAEPPLLARDGGFIAAGYDRELDEARTLRDEGRSVIAGLQKKYAEHTGISSLKIKHNNVLGYFIETTSTHAAKMQSAPMSDTYIHRQTTANQVRFTTVELSEIETKILNAGNLALEIEKRLYQRLSGAILDSAARLNQAARGFAEIDLVTALADLARAENWTRPRVDTSRAFHVDGGRHPVVEQALRHQGGDSFVANDCDLSPQDGAAIWLLTGPNMAGKSTFLRQNALIAVLAQMGSYVPAEAAHIGMISQLFSRVGASDDLARGRSTFMVEMVETAAILNQADDRALVILDEIGRGTATYDGLSIAWATLEHLHEVNRSRALFATHYHELTQLATKLTGVENATVSVKEWEGEVIFLHEVKKGAADRSYGVQVAQLAGLPASVVARARSVLDMLEKSSREGGGAGKVQIDDLPLFAAAPAPQPKPAQGPSPVEKLLEEIFPDDLTPREALETLYRLKDVSKG
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: DNAA_XANCP
Sequence: MDAWPRCLERLEAEFPPEDVHTWLKPLQAEDRGDSIVLYAPNAFIVEQVRERYLPRIRELLAYFAGNGEVALAVGSRPRAPEPLPAPQAVASAPAAAPIVPFAGNLDSHYTFANFVEGRSNQLGLAAAIQAAQKPGDRAHNPLLLYGSTGLGKTHLMFAAGNALRQANPAAKVMYLRSEQFFSAMIRALQDKAMDQFKRQFQQIDALLIDDIQFFAGKDRTQEEFFHTFNALFDGRQQIILTCDRYPREVEGLEPRLKSRLAWGLSVAIDPPDFETRAAIVLAKARERGAEIPDDVAFLIAKKMRSNVRDLEGALNTLVARANFTGRSITVEFAQETLRDLLRAQQQAIGIPNIQKTVADYYGLQMKDLLSKRRTRSLARPRQVAMALAKELTEHSLPEIGDAFAGRDHTTVLHACRQIRTLMEADGKLREDWEKLIRKLSE
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COL12_RAT
Sequence: MKDDFAEEEEVQSFGYKRFGIQEGTQCTKCKNNWALKFSIILLYVLCALLTITVAILGYKVVEKMDTVTDGMETSRQTYDNKLIAVESDLKKLGDQTGKKALSTNSELSTFRSDILDLRQQLQEITEKTSKNKDMLEKLQANGDSLVDRQSQLKETLQNNSFLITTVNKTLQAYNGYVTNLQQDTSVLQGNLQSQMYSQNVVIMNLNNLNLTQVQQRNLITNLQRSVDDTSLAIQQIKNDFQNLQQVFLQAKKDTDWLKEKVQSLQTLAANNSALAKANNDTLEDMNNQLSSFTGQMDNITTISQANEQSMKDLQDLHKDTENRTAVKFSQLEERFQVFETDIVNIINNISYTAHHLRTLTSNLNDVRTTCTDTLTRHTDDLTSLNNTLVNIRLDSISLRMQQDMMRSRLDTEVANLSVVMEEMKLVDSKHGQLIKNFTILQGPPGPRGPKGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGTIGPVGPPGERGSKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKDGLPGPQGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAMEPLALQNEPTPASEVNGCPPHWKNFTDKCYYFSVEKEIFEDAKLFCEDKSSHLVFINSREEQQWIKKQTMGRESHWIGLTDSEQESEWKWLDGTPVDYKNWKAGQPDNWGSGHGPGEDCAGLIYAGQWNDFQCDEINNFICEKEREAVPSSIL
What is the function of this protein?
Scavenger receptor that displays several functions associated with host defense.  Promotes binding and phagocytosis of Gram-positive, Gram-negative bacteria and yeast.  Mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells.  Binds to several carbohydrates including Gal-type ligands, D-galactose, L- and D-fucose, GalNAc, T and Tn antigens in a calcium-dependent manner and internalizes specifically GalNAc in nurse-like cells.  Binds also to sialyl Lewis X or a trisaccharide and asialo-orosomucoid (ASOR) (By similarity).
What are the official names of this protein?
Collectin-12, Collectin placenta protein 1, CL-P1, Nurse cell scavenger receptor 2.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein. Note=Forms clusters on the cell surface.
Protein: TOLB_XANC5
Sequence: MKKPLRWLAALTALLLPLSALAQQQGLTIDIVGGSASATPIAVIPMPYQGSGTAPQTDVSAVVGADLDRSGQFRTLPAAQIVEKPTRGTEVQFQTWRTLKQNYIVVGRVMDAGEGAYRVEYELFDVAKGERMLGLAMTARANAMRDVSHQMADAIYEKITGVRGAFWTRIAYVTASGKGGAMRYALMVADSDGYNPQTIVRSAEPLLSPNWSPDGKKLAYVSFERGNSSIYLQDIATGARELVSSFRGINGAPSFSPDGRRLALALSRSGNPEIYVMDLGSKQLTQLTNHFGIDTEPTWAPDGGSIYFTSDRGGRPQIYQVAASGGSANRVTFQGNYNATASVSFDGKKIAVAQGSGNTYRIAMMDRSLGSPSWSTLSPGSLDESPSFAPNASMVLYAAREGGRGVLYAVSSDARVRQRLVLADGDVREPAWGPYRTAH
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: HPRK_STRSL
Sequence: MTVTVKMLVDKLKLKVIYGNEKLLSKPITTADISRPGLEMTGYFDFYSPERIQLVGMKEWSYLKTLTDHNRYSVFSNMFKEETPAVIVARGLDIPEEMYRAAKENGVAVLQGRNGTSSLSGDMSWYLNAQLAERTSVHGVLVDIYGMGVLIQGDSGIGKSETGLELVKRGHRLVADDRVDVYAKDEETLWGEPAEILHHLLEIRGVGIIDVMSLYGASAVRNSSQVQLAIYLENFEDGKVFDRLGNGNEEIELQGVKIPRVRIPVKTGRNVSVVIEAAAMNYRAKQMGFDATKTFEERLTNLISKNGED
What is the function of this protein?
Catalyzes the ATP- as well as probably the pyrophosphate-dependent phosphorylation of 'Ser-46' in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).  The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc. ) in the growth medium.  Therefore, by controlling the phosphorylation state of HPr, the bifunctional HPr kinase/phosphorylase is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it probably mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: GCH1_CORA7
Sequence: MSDNIPAQREFDHERAEAAVRELLIAVGEDPDREGLRETPARVARAYAEVFAGLHQDPTEVLHKTFAEEHQELVLVRDIPIYSTCEHHLVPFYGTAHIGYIPGTDGHVTGLSKLARLADMYAKRPQVQERLTSQIADALVEVLHAQSVIVVIECEHLCMAMRGIRKPGATTTTSAVRGGFKKNAASRAEVMSLIRS
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: TCTP_CUCME
Sequence: MLVYQDLVSGDELLSDSFPYKEIENGMIWEVEGKWVVKGAVDVDIGANPSAEGGGEDEGVDDQAVKVVDIVDTFRLQEQPSMDKKVFLSCIKKYIKKLTPLLQGEQQEAFKNKIEGAVKYLLPKVKDLQFFVGESMADDSAMVFAYYKEGATDPTFLYIAPGLKEVKC
What is the function of this protein?
Involved in calcium binding and microtubule stabilization.
What are the official names of this protein?
Translationally-controlled tumor protein homolog, TCTP.
What is the protein family that this protein belongs to?
Belongs to the TCTP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASNA_STRZJ
Sequence: MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGMQDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPDEDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESILPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDYDDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLELEWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_BACCZ
Sequence: MAKRGKKYVEAAKLVDRAAAYSATEAVELVKKTNTAKFDATVEAAFRLGVDPKKADQQIRGAVVLPHGTGKVQRVLVFAKGEKAKEAEAAGADFVGDADYIGKIQQGWFDFDVVVATPDMMGEVGKLGRVLGPKGLMPNPKTGTVTFDVTKAVNEIKAGKVEYRVDKAGNIHVPIGKVSFEDAKLVENFRTIADTLQKVKPAAAKGTYMKNVTVASTMGPGVRVDVSTLA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: COPD_PONAB
Sequence: MVLLAAAVCTKAGKAIVSRQFVEMTRTRIEGLLAAFPKLMNTGKQHTFVETESVRYVYQPMEKLYMVLITTKNSNILEDLETLRLFSRVIPEYCRALEENEISEHCFDLIFAFDEIVALGYRENVNLAQIRTFTEMDSHEEKVFRAVRETQEREAKAEMRRKAKELQQARRDAERQGKKAPGFGGFGSSAVSGGSTAAMITETIIETDKPKVAPAPARPSGPSKALKLGAKGKEVDNFVDKLKSEGETIMSSSMGKRTSEASKMHAPPINMESVHMKIEEKITLTCGRDGGLQNMELHGMIMLRISDDKYGRIRLHVENEDKKGVQLQTHPNVDKKLFTAESLIGLKNPEKSFPVNSDVGVLKWRLQTTEESFIPLTINCWPSESGNGCDVNIEYELQEDNLELNDVVITIPLPSGVGAPVIGEIDGEYRHDSRRNTLEWCLPVIDAKNKSGSLEFSIAGQPNDFFPVQVSFVSKKNYCNIQVTKVTQVDGNSPVRFSTETTFLVDKYEIL
What is the function of this protein?
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.  Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.  In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity).
What are the official names of this protein?
Coatomer subunit delta, Archain, Delta-coat protein, Delta-COP.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.
Protein: DSG1B_MOUSE
Sequence: MDWHSFRIAALLLTSLVVLEVNSEFQIQVRDHNAKNGTIKWHSIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQPVTYRISGVGIDQPPYGIFIINQKTGEINITSIVDREVTPFFIIYCRALNAQGQDLENPLELRVRVMDINDNPPVFSMTTFLGQIEENSNANTLVMKLNATDADEPNNLNSMIAFKIIRQEPSDSPMFIINRKTGEIRTMNNFLDREQYSQYSLVVRGSDRDGGADGMSAESECSITILDVNDNIPYLEQSSYDIEIEENALHSQLVQIRVIDLDEEFSDNWKAIIFFISGNEGNWFEIEMNERTNVGTLKVVKPLDYEAMKNLQLSIGVRNVAEFHQSIISQYRLTATMVTVTVLNVIEGSVFRPGSKTFVVDSRMEANHRVGEFVATDLDTGRASTNVRYEMGNNPENLLVVDSRTGIITLRNRVTMEQYQRLNGEYKGTVLSIDDSLQRTCTGTIVIELSGTGWVPGSDGGGSSSGSGGNRDPVTNGYQGTSTVGPQRVTGSGGVTSSGGGSGVNNTPGRQNPLDEPEPEPFDITEDNVHFGPAGIGLLIMGFLVLGLVPFLLICCDCGGAPGGGAGFEPVPECSDGAIHTWAIEGPQPEPHDGITTICVPQMPPGNANVIEYIDNSGVYTNEYCGREMQDLGGGERTTGFELMDGVKTSAAPEICQEYSGTLRRNSMRECRDGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIEGVGSPAGSVGCCSFIGEDLDESFLDTLGPKFKKLADISLGKEIDSYPDPDSSWPPQSTEPMCPQSTEPLGSGYPPISPHFGTTTVISENAYPSGPGVQHPLPIPDPLGYGNVTVRESYATSGTLKPSVHFHDNQQASNVVVTERVVGPVPGADLHGMLEIPDLRDGTNVIVTERVIAPGSSLPTSLTIPNPRETSNVVVTERVIQPTSGMIGNLSMTPELSSAQNVIVTERVVSGAGMSGIAGTAGLGGVGGIGSSGLVSTTMGAAGTGLNMGGTATIGHMRSSSDHHFSQTIGSASPNMARSRITKYSTVQYSK
What is the function of this protein?
Component of intercellular desmosome junctions.  Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
What are the official names of this protein?
Desmoglein-1-beta, Dsg1-beta, Desmoglein-5.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome.
Protein: NADA_MYCGI
Sequence: MTVLAGTFDAALADRVVDGPGGFSGVDGDAAWADEVRRLLKLRGATLLAHNYQLPEIQDVADHVGDSLALSRIAAEVPEDTIVFAGVHFMAETAKILSPEKTVLIPDQRAGCSLADSITADELRAWKAEHPGAVVVSYVNTTAAVKAETDICCTSSNAVEVVASIPADREVLFCPDQFLGAHVRRITGRTNLHVWAGECHVHAGINGDELADQARAHPDAELYVHPECGCATSALYLAGEGAFPEDRVKILSTGGMLDAARETGARQVLVATEVGMLHQLRRAAPDVDFRAVNDRASCRYMKMITPAAMLRCLVEGADEVHVDPDMAAKARLSVQRMIEIGQPGGGE
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CP2A7_HUMAN
Sequence: MLASGLLLVALLACLTVMVLMSVWQQRKSRGKLPPGPTPLPFIGNYLQLNTEHICDSIMKFSECYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVAFSNGERAKQLLRFAIATLRDFGVGKRGIEERIQEESGFLIEAIRSTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEFLSLLSMMLGIFQFTSTSTGQLYEMFSSVMKHLPGPQQQAFKLLQGLEDFIAKKVEHNQRTLDPNSPQDFIDSFLIHMQEEEKNPNTEFYLKNLMMSTLNLFIAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRTKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVFPMLGSVLRDPSFFSNPQDFNPQHFLDDKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKSSQSPKDIDVSPKHVVFATIPRNYTMSFLPR
What is the function of this protein?
Cytochromes P450 are a group of heme-thiolate monooxygenases.  In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway.  It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
What are the official names of this protein?
Cytochrome P450 2A7, CYPIIA7, Cytochrome P450 IIA4.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: DCTN3_MOUSE
Sequence: MAALTDVQRLQSRVEELERWVYGPGGTRGSRKVADGLVKVQVALGNIASKRERVKILYKKIEDLIKYLDPEYIDRIAIPEASKLQFILAEEQFILSQVALLEQVNALVPVLDSASIKAVPEHAARLQRLAQIHIQQQDQCVAITEESKALLEGYNKTTMLLSKQFVQWDELLCQLEAAKQVKPAEE
What is the function of this protein?
Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules (By similarity).  Together with dynein may be involved in spindle assembly and cytokinesis (By similarity).
What are the official names of this protein?
Dynactin subunit 3, Dynactin light chain p24.
What is the protein family that this protein belongs to?
Belongs to the dynactin subunit 3 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Cleavage furrow. Midbody. Note=Localizes to punctate cytoplasmic structures and to the centrosome during interphase, and to kinetochores and to spindle poles throughout mitosis. Colocalizes with dynein to the cleavage furrow and to midbody of dividing cells (By similarity).
Protein: CEMA_HELAN
Sequence: MAKKKAFTPLLYLVSIVFLPWWISLLFQKSLESWVTNWWNTRQSETFLNDIEEKSILEKFIELEELLFLEEMIKEYSETHLQNLRIGIHKETIQLIKIQNEGRIHTILHFSTNIICFIILSGYSILGNKELVILNSWAQEFLYNLSDTIKAFSLLLLTDLCIGFHSPHGWELMIGFVYKDFGFVHNDQIISGLVSTFPVILDTILKYWIFRYLNRVSPSLVVIYHSMND
What is the function of this protein?
May be involved in proton extrusion.  Indirectly promotes efficient inorganic carbon uptake into chloroplasts.
What are the official names of this protein?
Chloroplast envelope membrane protein.
What is the protein family that this protein belongs to?
Belongs to the Cema family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: ENO_ACAM1
Sequence: MHETEIAAIEAREILDSRGRPTVEAEVILSCGAFGLAQVPSGASTGSFEAHELRDGDAQRYGGKGVLTAVTNIKDHIQPELVGLNALDQADIDQTMIDLDGSTNKSKLGANAILAVSLATAKAASEVLNLELYRYLGGPLANLLPVPLMNVINGGAHANNNVDIQEFMIVPHGADSFKEALRWGAEVFASLSQVLAAQNLLTGVGDEGGYAPNLASNQAALELLVEAIEKAGYQPGAQISLALDVAASEFYKDGQYTYDGAAHSPKELIDYLDGLASKYPIVSIEDPLHEEDWESWGNLTAQLGDRVQLVGDDLFVTNPIRLQKGIEQQSANSILIKLNQIGTLTETLETIDLAKRNSFTSIISHRSGETEDTTIADLAVATRAGQIKTGSLCRSERVAKYNRLLRIEDELGSQASYAGAVGLGPG
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: SPEE_HELAH
Sequence: MWITQEITPYLRKEYTIEAKLLDVRSDHNILEIFKSNDFGEIAMLNSQLLFKNFLHIESELLAHMGGCTKKELKEVLIVDGFDLELAHQLFKYDTHVDFVQADEKILDSFISFFPHFHGVKNNKNFTHAKQFLDLDIKKYDLIVCLQEPDKHKIDGLKRTLKEDGVFISVAKHPLLEHVSMQNALKNMGEFFSIVMPFVAPLRILSNKGYIYASLKTHPLKDLIAQKIEALKNVGYYNEDIHRAAFALPKNLQEILKENIKS
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CESA2_ORYSJ
Sequence: MDGAKSGKQCHVCQICGDGVGTAADGELFTACDVCGFPVCRPCYEYERKDGSQACPQCKTKYKRHKGSPPILGDESDDVDADDASDVNYPTSGNQDHKHKIAERMLTWRMNSGRNDDIVHSKYDSGEIGHPKYDSGEIPRIYIPSLTHSQISGEIPGASPDHMMSPVGNIGRRGHPFPYVNHSPNPSREFSGSLGNVAWKERVDGWKMKDKGAIPMANGTSIAPSEGRGVGDIDASTDYNMEDALLNDETRQPLSRKVPISSSRINPYRMVIVLRLIVLCIFLHYRITNPVRNAYPLWLLSVICEIWFALSWILDQFPKWSPINRETYLDRLALRYDREGEPSQLAPVDIFVSTVDPMKEPPLVTANTVLSILAVDYPVDKVSCYVSDDGAAMLTFDALAETSEFARKWVPFCKKYSIEPRAPEWYFAQKIDYLKDKVQASFVKDRRAMKREYEEFKVRVNALVAKAQKVPEEGWIMQDGTPWPGNNTRDHPGMIQVFLGHSGGLDTEGNELPRLVYVSREKRPGFQHHKKAGAMNALVRVSAVLTNGQYLLNLDCDHYINNSKALREAMCFLMDPNLGRRVCYVQFPQRFDGIDRNDRYANRNTVFFDINLRGLDGLQGPVYVGTGCVFNRTALYGYEPPIKQKRPGYFSSLCGGRKKTKKSKEKSTEKKKSHKHVDSSVPVFNLEDIEEGIEGSGFDDEKSLLMSQMSLEKRFGQSSVFVASTLMEYGGVPQSATPESLLKEAIHVISCGYEDKSDWGTEIGWIYGSVTEDILTGFKMHARGWRSIYCMPKRPAFKGSAPINLSDRLNQVLRWALGSVEILFSRHCPIWYGYGGRLKFLERFAYINTTIYPLTSIPLLLYCILPAICLLTGKFIIPEISNFASIWFISLFLSIFATGILEMRWSGVGIDEWWRNEQFWVIGGISAHLFAVFQGLLKVLAGIDTSFTVTSKASDEEGDFAELYMFKWTTLLIPPTTILIINLVGVVAGISYAINSGYQSWGPLFGKLFFAFWVIVHLYPFLKGLMGRQNRTPTIVVVWAILLASIFSLLWVRIDPFTTRVTGPDTQKCGINC
What is the function of this protein?
Probable catalytic subunit of cellulose synthase terminal complexes ('rosettes'), required for beta-1,4-glucan microfibril crystallization, a major mechanism of the cell wall formation.
What are the official names of this protein?
Probable cellulose synthase A catalytic subunit 2 [UDP-forming], OsCesA2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. Plant cellulose synthase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.