PharMolix/UniProtQA huggingface dataset:
Protein: OPSX_MOUSE
Sequence: MLSEASDFNSSGSRSEGSVFSRTEHSVIAAYLIVAGITSILSNVVVLGIFIKYKELRTPTNAVIINLAFTDIGVSSIGYPMSAASDLHGSWKFGHAGCQIYAGLNIFFGMVSIGLLTVVAMDRYLTISCPDVGRRMTTNTYLSMILGAWINGLFWALMPIIGWASYAPDPTGATCTINWRNNDTSFVSYTMMVIVVNFIVPLTVMFYCYYHVSRSLRLYAASDCTAHLHRDWADQADVTKMSVIMILMFLLAWSPYSIVCLWACFGNPKKIPPSMAIIAPLFAKSSTFYNPCIYVAAHKKFRKAMLAMFKCQPHLAVPEPSTLPMDMPQSSLAPVRI
What is the function of this protein?
May play a role in rpe physiology either by detecting light directly or by monitoring the concentration of retinoids or other photoreceptor-derived compounds.
What are the official names of this protein?
Visual pigment-like receptor peropsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ILVC_XANP2
Sequence: MRVYYDRDADLNLIKGKKVAVVGYGSQGHAHALNMRDSGVKEVVVALRPGSATAKKAEAEGFKVMSPADAAKWADVVMMLTPDELQGDIYRESLADNMKHGAALLFAHGLNVHFNLIEPRPDLDVLMVAPKGPGHTVRSEYQRGGGVPTLIAIAQDASGNAHDLGLSYASAIGGGRAGVIETTFKEECETDLFGEQVVLCGGLVELIRAGFETLVEAGYAPEMAYFECLHEVKLIVDLIYEGGIANMNYSISNTAEYGEYVTGPRIITPETKAEMKRVLTDIQTGKFTRDWMLENKVNQASFKATRARANAHPIEEVGEKLRAMMPWIKAKALVDKTKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: EXO84_CRYNB
Sequence: MASLRRPSTAIPRGPASVQFDRGARPPLPNDNKQKRMSKVGEKIKKRLSMRYGGNESFSVPPPLPGASDFLTADPYGGLDIETPGEDLAASPFGLYGASDLKESSIQSSQPLDTQEHLVDESIGRRGAADATLEEEWNLEELSNEKVDAQAYVKKVLTGADEEEKRRFVAALMREKQANKKELQRTVFKHYAEFVAISKEISTLENDMLELKELLGQWKDLPQLMGMEDTLAPTLDRNGNLERRRTQRKSVFDLQNLYRNQLTQLWSIVEGSQKYLPVVAGRHLVFELHGVVELNPATYKPKQNVSIFLLNDVLLIAGKRRNKGGSTTSVGDEKDRDRGRMVAERCWNLIELGIVDVKDGGELVNVIKVHRGKEHCVYRTQKSDDKRALINAFRQISREANEKKRKDSEKEQERRKTMWLGDKNGNGTGNSGHPLSTIGPSMADSKDLRWIDEYGDELTMAIAIRDWEESVKLVEKGQALSKSIESNSSAHSLLVSRLEQLVPSLVSQISHDLSSSNLRKSSSARLISLLVRLDLADHARDSFLESRRELMFKRVRSIKCDGDVSIYINELAVVIFTIIRHTSDWYMNAFKENNMASGFVTWAKQQIETFADLFRRQMDAPNISESTVNECLHVTATQNRKLLRDVGLDFTFLLSSLLQPSSNPSDYPHSVFTSV
What is the function of this protein?
Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis.  Plays a role in both the assembly of the exocyst and the polarization of this complex to specific sites of the plasma membrane for exocytosis.  Also involved in assembly of the spliceosome (By similarity).
What are the official names of this protein?
Exocyst complex component EXO84.
What is the protein family that this protein belongs to?
Belongs to the EXO84 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle. Note=Cell periphery. The polarization of EXO84 requires actin cables (By similarity).
Protein: Y651_LEVBA
Sequence: MTEDIRLVIITGMSGAGKTVAMQSFEDLGYFCIDNMPPSLLPKFWDLVRESGKLSKIALVIDLRSRAFYDEIVRMLNDVAVHGTMNAQVLFLDASDAELVSRYKETRRSHPLARNGRVLEGISRERELLAPIRQAAQLVIDTTKLSPRKLREEIFHNYETETTQAFHIELMSFGFKYGLPIDADIVMDVRFLPNPYYLPELRNQTGMDQPVYDYVMNQPQTEEFYQRFLGLLTTIVPGYKQEGKSSLTIAIGCTGGQHRSVALTQRLGQALGNTYPVHVTHRDIEKRKESANRS
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein LVIS_0651.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: RL3_ACICJ
Sequence: MSVMRTGIIAKKLGMTRLFREDGTHVPVTVLHMDDVRVVAARTKERDGYAAVQLGFGHAKTKNVTKPMKGHFAAAKVEPANRLVEFRVADDAVLEAGQVLSAAHFTVGQKVDVAGISKGKGFAGGMKRWNFRGLEASHGVSISHRSLGSTGNRQDPGKTFKNKKMAGHLGGERITTLNLEVAAIDEARNLIMIKGAVPGAKDGYVLVRDAVKTARPADAAYPAALKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: SOAT_RAT
Sequence: MSADCEGNSTCPANSTEEDPPVGMEGQGSLKLVFTVLSAVMVGLVMFSFGCSVESRKLWLHLRRPWGIAVGLLCQFGLMPLTAYLLAIGFGLKPFQAIAVLIMGSCPGGTVSNVLTFWVDGDMDLSISMTTCSTVAALGMMPLCLYVYTRSWTLPQSLTIPYQSIGITLVSLVVPVASGIYVNYRWPKQATFILKVGAAVGGMLLLVVAVTGVVLAKGWNIDVTLLVISCIFPLVGHVMGFLLAFLTHQSWQRCRTISIETGAQNIQLCIAMMQLSFSAEYLVQLLNFALAYGLFQVLHGLLIVAAYQAYKRRQKSQYRRQHPECQDISSEKQPRETSAFLDKGAEAAVTLGLEQHHRTAELTSHVPSCE
What is the function of this protein?
Transports sulfoconjugated steroid hormones from the extracellular compartment into the cytosol in a sodium-dependent manner without hydrolysis (PubMed:15020217).  Steroid sulfate hormones are commonly considered to be biologically inactive metabolites, that may be activated by steroid sulfatases into free steroids (By similarity).  May play an important role by delivering sulfoconjugated steroids to specific target cells in reproductive organs (By similarity).  May play a role transporting the estriol precursor 16alpha-hydroxydehydroepiandrosterone 3-sulfate (16a-OH-DHEAS) at the fetal blood vessel endothelium (By similarity).  Can also transport other sulfoconjugated molecules such as taurolithocholic acid-3-sulfate and sulfoconjugated pyrenes (By similarity).
What are the official names of this protein?
Sodium-dependent organic anion transporter, Soat, Solute carrier family 10 member 6, SLC10A6.
What is the protein family that this protein belongs to?
Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL5_MYCS2
Sequence: MTTTEKALPRLKQRYREEIREALQQEFNYANVMQIPGVVKVVVNMGVGDAARDAKLINGAINDLALITGQKPEVRRARKSIAQFKLREGMPIGARVTLRGDRMWEFLDRLISIALPRIRDFRGLSPKQFDGTGNYTFGLNEQSMFHEIDVDSIDRPRGMDITVVTTATNDAEGRALLRALGFPFKEN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: RSMA_ECOL6
Sequence: MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEIGPGLAALTEPVGERLDQLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTFNFGELAAKMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRLSVMAQYYCNVIPVLEVPPSAFTPPPKVDSAVVRLVPHATMPHPVKDVRVLSRITTEAFNQRRKTIRNSLGNLFSVEVLTGMGIDPAMRAENISVAQYCQMANYLAENAPLQES
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAO1_ECOUT
Sequence: MEPKTKKQRSLYIPYAGPVLLEFPLLNKGSAFSMEERRNFNLLGLLPEVVETIEEQAERAWIQYQGFKTEIDKHIYLRNIQDTNETLFYRLVNNHLDEMMPVIYTPTVGAACERFSEIYRRSRGVFISYQNRHNMDDILQNVPNHNIKVIVVTDGERILGLGDQGIGGMGIPIGKLSLYTACGGISPAYTLPVVLDVGTNNQQLLNDPLYMGWRNPRITDDEYYEFVDEFIQAVKQRWPDVLLQFEDFAQKNAMPLLNRYRNEICSFNDDIQGTAAVTVGTLIAASRAAGGQLSEKKIVFLGAGSAGCGIAEMIIAQTQREGLSEEAARQKVFMVDRFGLLTDKMPNLLPFQTKLVQKRENLSDWDTDSDVLSLLDVVRNVKPDILIGVSGQTGLFTEEIIREMHKHCPRPIVMPLSNPTSRVEATPQDIIAWTEGNALVATGSPFNPVVWKDKIYPIAQCNNAFIFPGIGLGVIASGASRITDEMLMSASETLAQYSPLVLNGEGLVLPELKDIQKVSRAIAFAVGKMAQQQGVAVKTSAEALQQAIDDNFWHAEYRDYRRTSI
What are the official names of this protein?
NAD-dependent malic enzyme, NAD-ME.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
Protein: SYI_COXBN
Sequence: MTDYKDTLNLPQTDFPMRANLPEREPQTLARWQTLDLYRKIRKDREGQPKFILHDGPPYANGRAHLGTAFNKTLKDIVVKSKTLSGFDAPFVPGWDCHGLPIELNVEKKLGKDKLSANAFRQACRDYAFSQIELQRDDFQRLGVLGDWQHPYLTMDFGYEADTVRALAKIVANGHLLRGQKPVHWCAACGSALAEAEVEYRDKASPAVDVGFEAVDAEAVRQRFGVKNATTRVLVPIWTTTPWTLPANEAVSVHPELHYALVKSELQNQPVYLILAKDLVDSAMQRYGVDDYEVHGNLKGDALEGMQLQHPFLDRIVPIILGEHVTTEAGTGNVHTAPAHGLEDYFVAEKYNLPINNPVDARGRFIPDTFLVGGQPVFKANEPIIVLLADSGHLLHSETIQHSYPHCWRHKTPLIFRTTPQWFIGMNKNGLRERALAEIEKVTWLPAWGEARIGKMVADRPDWCISRQRLWGIPIPLFIHKKSGELHPKSPALMEKVAQLIEKESVDAWFDLDPKVLLGDDADHYEKVTDVLDVWFDSGVTHFCVLEKRRELKVPADIYLEGSDQHRGWFQSSLLTSLAIRDKAPYKSVLTYGFVVDSQGRKMSKSLGNVILPADVVKNLGADVLRLWAASMDYTVEVNVSDEILKRASDAYRRIRNTARFLLSNLYDFDPKKDKVAVDQLVALDRWAIFTTQKLQEKIITAYDRYRFPAIYQAIHNFCTVEMGSFYLDIIKDRLYTSKESGLPRRSAQTALYYIAEAFVRWIAPIISFTADEIWQFMPGDREPSVFLTQWFSDFPNAALSGEEEQRWQLLLQIRDEVNKALETYRNEGKIGSALAAEVVLYADERLNAAIATLGEELRFVLITSEASVLPFNEKSKAAFDTALPGLALEINVSEFEKCARCWQRRSSVGQIKEHADLCDRCVSNAFEDGEMRQFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIT1_ONCMY
Sequence: MSCQAFSADSFTTLAGDSLPLLMHHASAADCLPSSASTHTHNMVSAVPSGLSLLQSSKRSHMHLSTSTLGNALSNGPPGLHYPVTPCHYSNQQTTYGMMAAQEMLSASISQTRILQTCSVPHPNMVNGANTLQGSLAPCLYKFPEHGLGGGSCSLSHSFPPLPPAVLSEEPPLGGTKDLRLRSRPPDDPPDMDSPQIRELEKFANDFKLRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQLSFKNACTLKAILAKWLDEAEQAGALFNEKMGMNERKRKRRTTISLGAKEALERSFGEKIKPSSQEIVRMAEGLHLEKEVVRVWFCNRRQREKRVKTSLHHSSYLTKDSPTYR
What is the function of this protein?
Transcription factor that activates growth hormone and prolactin genes.  Specifically binds to the consensus sequence 5'-TAAAT-3'.
What are the official names of this protein?
Pituitary-specific positive transcription factor 1, PIT-1, Growth hormone factor 1, GHF-1.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: VATB_THEP3
Sequence: MLREYKTVREIVGPLMLVEKVEGVKYNELVEIETGTGEIRRGQVLEVNGDKALVQLFEGSTGLNINDCKVRFVGKSIELGVSIDMLGRVFDGLGRPRDKGPMIIPEKRLDINGNPINPTARDYPSEFIQTGISAIDGLNTLVRGQKLPIFSGSGLPHAQLAAQIARQAKVLGSDSKFAVVFAAMGITFEEADYFISDFRRTGAIDRSVLFINLANDPAIERIATPRMALTCAEFLAYEKEMHVLVIMTDMTNYCEALREVSAARKEVPGRRGYPGYLYTDLATIYERAGRIKGRKGSITQIPILTMPEDDKTHPIPDLTGYITEGQIILSRDLYRKGIYPPIDVLPSLSRLKDKGIGQGKTREDHADLMNQLFASYARGKQAKELAVILGEAALSDTDKLYAKFADEFEARYVAQREDEDRSIEETLAIGWDLLTILPRAELKRVRDEYIDKYLPEKGE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type beta chain is a regulatory subunit.
What are the official names of this protein?
V-type ATP synthase beta chain, V-ATPase subunit B.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: RS16_ALKCK
Sequence: MAVKIRLKRMGSKKAPFYRVVVADSRFPRDGRFIEEIGTYNPIAQPAQVNIKEDKALEWMKKGAKPSDTVRSLFSNAGLMEKLHNEKNGK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: RL13_XANAC
Sequence: MTTFTAKSETVQRDWYLVDAAGKTLGRLSTELARRLRGKHKPVYTPHVDTGDYLVVINAEKIVVTGNKLKDKKYHRFTGYIGNLKTESLEQALQRHPERVIEIAVKGMLPKGPLGRTMYRKLKVYSGAEHPHAAQQPQVLDI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: TRUB_MYCTO
Sequence: MSATGPGIVVIDKPAGMTSHDVVGRCRRIFATRRVGHAGTLDPMATGVLVIGIERATKILGLLTAAPKSYAATIRLGQTTSTEDAEGQVLQSVPAKHLTIEAIDAAMERLRGEIRQVPSSVSAIKVGGRRAYRLARQGRSVQLEARPIRIDRFELLAARRRDQLIDIDVEIDCSSGTYIRALARDLGDALGVGGHVTALRRTRVGRFELDQARSLDDLAERPALSLSLDEACLLMFARRDLTAAEASAAANGRSLPAVGIDGVYAACDADGRVIALLRDEGSRTRSVAVLRPATMHPG
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, MTB-TRUB, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: YL88_SCHPO
Sequence: MHTYCNTETVQLYRFIAMDQWSDNKDAIGMLSESLKEKVVTNEIAPALKEVKNHKYNFETEILNTGNVWNNDSKNGESGSAFGLDKIFQSSDSGNIAEGLELDLGNIMLETHNLESPAWKHADYDGVAASVNDNNNDWKFFVFDEREIDSMLQLFVRDFRADKPALRLAPSKLFYLASRFAFFYMPKEKELGTVLLNAFLCEVNQVTQQHPNDMVLCVQWLANVSLLLFYLKKDNKLDDLTVDIQNRCSELMNSLYITICQDAMRRMNENLEEGMVKYTGIQGLEDILRSRSWNLLRRRPTNDASTSPRSTPSASPRSITKIIASTLHLLEVFYIHPLIRAQCIEQLFSWLGARLFNIVISNKKYLSRAAAMETRFNISSLEEWSQTNSPKLQKPFDYPDEDLKVDLISKLLSLVQLLQWLQCLYRLSEDEDPRALQETLESLDALNPRQIYTAAKLYRPDITETKVSKTFLKKLDAFHEEKLREKINSSDKGDVSYEFELLKDETVFSPLKLPTKAQLINAYSYIVSGNGFNEDRKIVFQPHVSNILIDKLEENGLSMERAELPTSVFEDELQRREWRPDQEVEELLST
What are the official names of this protein?
Dilute domain-containing protein C25B8.08.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus.
Protein: C71BN_ARATH
Sequence: MSIFLCFLLLLLLLLVTIIFTRKSQSSKLKLPPGPPKLPIIGNLHYLNGLPHKCLLNLWKIHGPVMQLQLGYVPLVVISSNQAAEEVLKTHDLDCCSRPETIASKTISYNFKDIGFAPYGEEWRALRKLAVIELFSLKKFNSFRYIREEENDLLVKKLSEASEKQSPVNLKKALFTLSASIVCRLAFGQNLHESEFIDEDSMEDLASRSEKIQAKFAFSNFFPGGWILDKITGQSKSLNEIFADLDGFFNQVLDDHLKPGRKVLETPDVVDVMIDMMNKQSQDGSFKLTTDHIKGIISDIFLAGVNTSATTILWAMTELIRNPRVMKKVQDEVRTVLGEKRDRITEQDLNQLNYFKLVIKETFRLHPAAPLLLPREAMAKIKIQGYDIPEKTQIMVNVYAIGRDPDLWENPEEFKPERFVDSSVDYRGLNFELLPFGSGRRICPGMTMGIATVELGLLNLLYFFDWGLPEGRTVKDIDLEEEGAIIIGKKVSLELVPTRRQ
What are the official names of this protein?
Cytochrome P450 71B23.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RHO_RICBR
Sequence: MSITNKESPEQLNNPEFNNHYAENGNIINLKELKRKLPEELQAQAEELKIENVSSLRKQELVFAILKKSVEQGGSIVGEGVLEVLPDGFGFLRSPEVNYLAGPDDIYISPSQIRRFGLRTGDTVEGRIRAPKEGERYFALLKVNKVNFEDPSKAYHRVNFDNLTPLYPDEKLGLELEDNSKDFSTRVIELVAPMGKGQRALIVAPPRTGKTVLLQNIAHAITTNNPEVFLIVLLIDERPEEVTDMQRSVRGEVVSSTFDEPASRHVQLAEMVIEKAKRLVEHKKDVVILVDAITRLARAYNTVVPSSGKVLTGGVDANALQRPKRFFGAARNIENGGSLTIIGTALIETGSRMDEVIFEEFKGTGNSEIVLDRKIADKRIYPAIDITRSGTRKEDLLVDKIVLNKMWVLRRIIDPMGSSEAIEFLLKKLEHTKTNNEFFEMMKSPAERK
What is the function of this protein?
Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
What are the official names of this protein?
Transcription termination factor Rho, ATP-dependent helicase Rho.
What is the protein family that this protein belongs to?
Belongs to the Rho family.
Protein: COXX_STRGG
Sequence: MTAVESRPAGVALTPSPGAHRPSGARVKAFVALTKPRIIELLLITTVPVMFLAAQGVPDLWLVLTTTIGGYLSAGGANALNMYIDRDIDALMDRTSQRPLVTGMVTPRECLAFGIALAVISTVWFGLLVNWLSAALALGALLFYVVVYTMLLKRRTSQNIVWGGIAGCMPVLIGWSAVTNELSWAAVILFAVIFFWTPPHYWPLSMKVKDDYARVGVPMLPVVATNRVVAKQIVLYSWVMVAVSLLLTPLGYTGWFYTAVALLSGGAWLWEAHGLQNRAKAGVTGAKLKEMRLFHWSITYVSLLFLAVAVDPFLR
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RR19_LACSA
Sequence: MTRSLKKNPFVANNLLKKINKLNTKAEKEIIITWSRASTIIPIMVGHTIAIHNGKEHLPIYITDRMVGHKLGEFAPTLNFRGHAKSDNRSRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ETF2_FOWPN
Sequence: MYVVNPQLVVLVDKDQEILDVLYLTLYDGIDERSSMYYFIKNHLRVPMDRVRVLKKHIILTLKISQVKGYICDLLNIDEEIIIYSHKNNLEYSYVDNTTFNPFTMTQRKTLLKSKSFLYNVYVDACNFLVIWVAKAADTMVKELGSYEEVDANVLKFESRLIEMFPDLDLDFTVESKFNNVFRTNLKMTGLKNIVLSNTDKKILFIKSDEYFINLSGNHFVINDESLNLSIWDDDGSLAISSDGNTITVNNVKLFTDMIPNNNVQMERIKSDITYKVKLSTPITSKVKLDIETSFIFIETATNNILLSVDKKISIILAKNHISIKVKNHIPNIEKYFTFLVVFINRLFNTVKQSMDFTKIETIYWSRICQNTKDKNRKPVIISSLEPDMLKVSDNFYKSPTKEVFVNNNEVMFTCDDKTGKYNNIGFLAIFYKLQKICIPCCFLKNQSHTDTFMACVHNKQTDKNIISPYILNYGKVVTDSKIAFLPPIFNDFFNSDLSISLESDNKRLKSTKGYHVIRSCLHNCRYYTLKRIRTKNDIIQFVNTENVTLIANDIVYFPMKYSSINNKIYILVQEIVHEIVIAKKEEDKDMIYFEELRTNKLRDMFPYKVKTVDIKEQNGLKLTTDGFYVDGELFTEPLSTKRSVFMDNISTQNNPIVKYFNSVFKYVVTDNKEIFIKTWVINTMLKLGIGKDYTHIQIKSILEKYYKL
What is the function of this protein?
Acts with RNA polymerase to initiate transcription from early gene promoters.  Is recruited by the RPO-associated protein of 94 kDa (RAP94) to form the early transcription complex, which also contains the core RNA polymerase.  ETF heterodimer binds to early gene promoters (By similarity).
What are the official names of this protein?
Early transcription factor 82 kDa subunit, ETF large subunit.
What is the protein family that this protein belongs to?
Belongs to the poxviridae VETF large subunit family.
What are the subcellular locations of this protein?
Virion. Note=All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome. This is necessary because viral early mRNAs are synthesized within minutes after virus entry into the cell and are extruded through pores in the core particle (By similarity).
Protein: RUVC_BURCH
Sequence: MRILGIDPGLRVTGFGVIDVSGHRLAYVTSGVIRTPTADLATRLGTIFQGVSTIVREHAPDQAAIEKVFVNVNPQSTLLLGQARGAAICGLVAGGLPVAEYTALQLKQAVVGYGRATKTQMQEMVTRLLNLSGQPGSDAADALGMAICHAHGGNTLSTLGGLAPALAQKGLRVRRGRLVG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: TIG_XANOM
Sequence: MQASIESTGNLERRLTFTLPQERLETHVGGRLRELARTTRIKGFRPGKVPTKVIEQRFGQQVRAEAMEGLLRETFDSAVREHSLRLAGNPRIDQGETDFDFVATFEVVPDFGDIDVTTLSVVRATAEVTDADIDQMIENLRLQRRIWNPVERGAQAGDLVALETWSQAGDERLPADGVETGSSVLGSGVMFDQIEKGLEGLTKGEEKTLSVDFPAEWRVPQLAGKTVQVHVKAVEVSEPVLPAVDKEFIKSFGVKSGDAEQFRADIRTNLERELKGALMNRLRREVGEQLIAAYAHVEMPPRLVENEARSMLAQQVEQVRRSGRDPGQVPADAHQGFMDAAAKRVLVGLLVGEVARRNELRLESRRVSDTLRLIASTYEEPEQVIEMYRNDPQLMNGLQSRVMKEQVIDWIAERAQHTEQSLSFQDAIRV
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: NADD_CLOBK
Sequence: MINKAILGGTFDPIHNAHINVAYEALERFNLEEVIFIPAGNPPHKINLKKTPAHIRYEMVKLAIEKETRFSISDFEIKSKSLSYTYRTLKHFKEKEPETNWYFITGEDCLSYLEHWKYIDEIFNICNFVIFSREGFKEKEEIIKKKKSILLKYRKEILFMDASILDISSTKIRNRIKEGKEVSFYMPDKVYKFILQNNLYK
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: ATPB_RICCN
Sequence: MTKNIGKITQIISAVVDVKFTNNGELPKILNALECYNDKQRIVLEVAQHIGDDTVRCIAMDSMEGLVRGVEVIDTGSPIRIPVGTETLGRIMNVVGEPIDGKGDIKSSNISSIYKPAPDFTHQSTECNILVTGIKVIDLLAPYTKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYTVFAGVGERTREGNDLYHEMIDSGVINLAEPEKSKVALVYGQMNEPPGARARVALSGLTIAESFRDMNEGQDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGELQERITSTKYGSITSVQAIYVPADDLTDPAPATSFAHLDATTVLSRQIAEFGIYPAVDPLDSNSQVLDPMIVGEEHYSVARQVQQVLQTYKSLQDIITILGMDELSEEDKLTVARARKIQRFLSQPFHVAEVFTGAAGKFVNLADTIAGFKGLVEGKYDDLPEAAFYMVGTIDEAIEKAQTLK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.