PharMolix/UniProtQA huggingface dataset:
Protein: COPG2_HUMAN
Sequence: MIKKFDKKDEESGSGSNPFQHLEKSAVLQEARIFNETPINPRRCLHILTKILYLLNQGEHFGTTEATEAFFAMTRLFQSNDQTLRRMCYLTIKEMATISEDVIIVTSSLTKDMTGKEDVYRGPAIRALCRITDGTMLQAIERYMKQAIVDKVSSVSSSALVSSLHMMKISYDVVKRWINEAQEAASSDNIMVQYHALGVLYHLRKNDRLAVSKMLNKFTKSGLKSQFAYCMLIRIASRLLKETEDGHESPLFDFIESCLRNKHEMVIYEAASAIIHLPNCTARELAPAVSVLQLFCSSPKPALRYAAVRTLNKVAMKHPSAVTACNLDLENLITDSNRSIATLAITTLLKTGSESSVDRLMKQISSFVSEISDEFKVVVVQAISALCQKYPRKHSVMMTFLSNMLRDDGGFEYKRAIVDCIISIVEENPESKEAGLAHLCEFIEDCEHTVLATKILHLLGKEGPRTPVPSKYIRFIFNRVVLENEAVRAAAVSALAKFGAQNESLLPSILVLLQRCMMDTDDEVRDRATFYLNVLQQRQMALNATYIFNGLTVSVPGMEKALHQYTLEPSEKPFDMKSIPLAMAPVFEQKAEITLVATKPEKLAPSRQDIFQEQLAAIPEFLNIGPLFKSSEPVQLTEAETEYFVRCIKHMFTNHIVFQFDCTNTLNDQLLEKVTVQMEPSDSYEVLSCIPAPSLPYNQPGICYTLVRLPDDDPTAVAGSFSCTMKFTVRDCDPNTGVPDEDGYDDEYVLEDLEVTVSDHIQKVLKPNFAAAWEEVGDTFEKEETFALSSTKTLEEAVNNIITFLGMQPCERSDKVPENKNSHSLYLAGIFRGGYDLLVRSRLALADGVTMQVTVRSKERTPVDVILASVG
What is the function of this protein?
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.  Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.  In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity).
What are the official names of this protein?
Coatomer subunit gamma-2, Gamma-2-coat protein, Gamma-2-COP.
What is the protein family that this protein belongs to?
Belongs to the COPG family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it. Tends to be more abundant in the trans-Golgi network compared to the cis-Golgi.
Protein: SBH1_ARATH
Sequence: MMMGFAVSDELLGTVAPIVVYWLYSGIYVALSSLESYRLHSKVEEEEKNLVSKSSVVKGVLVQQVVQAVVAILLFTVTGSDAEADKAQQFSFLVLARQFVTAMIVLDTWQYFMHRYMHQNKFLYKHIHSQHHRLIVPYAYGALYNHPVEGLLLDTIGGALSFLVSGMSPRTSIFFFSFATIKTVDDHCGLWLPGNLFHMVFKNNSAYHDIHHQLYGTKYNFSQPFFVMWDRILGTYMPYSLEKREDGGFEARPTKEFKDD
What is the function of this protein?
Involved in sphingolipid trihydroxy long-chain base (4-hydroxysphinganine) biosynthesis.  Can use C18- and C20-sphinganine as substrates to produce C18- and C20-phytosphinganines (D-ribo-2-amino-1,3,4-trihydroxyoctadecane and -eicosane).
What are the official names of this protein?
Sphinganine C4-monooxygenase 1, Sphingoid C4-hydroxylase 1, Sphingoid base hydroxylase 1.
What is the protein family that this protein belongs to?
Belongs to the sterol desaturase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PSBL_PLETE
Sequence: MAKSNPNKQSVELNRTSLYWGLLLIFVLAVLFSSYIFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: PAS1_ARATH
Sequence: MAVGDQTEQNYLPKKKKSETEDDKRRKKIVPGSLLKAVVRPGGGDSSPVDGDQVIYHCTVRTLDGVVVESTRSESGGRGVPIRDVLGNSKMILGLLEGIPTMHKGEIAMFKMKPEMHYAEIDCPVSAPENFPKDDELHFEIELLDFSKAKIASDDLGVIKKILNEGEGWESPREPYEVKARISAKSGDGHVIFSHTEEPYFFTFGKSEVPKGLEIGIGTMARKEKAVIYVRKQYLTESPLLHIDQDLEEVHFEVELVHFIQVRDMLGDGRLIKRRIRDGRGEFPMDCPLQDSRLSVHYKGMLLNEEKTVFYDSKIDNNDQPLEFSSGEGLVPEGFEMCTRLMLPGEIALVTCPPDYAYDKFPRPPGVSEGAHVQWEIELLGFETPRDWTGLNFQSIMDEADKIRSTGNRLFKEGKFELAKAKYEKVLREFNHVNPQDEDEGKIFGDTRNMLHLNVAACLLKMGEWRKSIETCNKVLEAKPGHVKGLYRRGMAYIAGGEYDDARNDFNMMIKVDKSSEADATAALLKLKQKEQEAESKARKQFKGLFDKRPGEITEVGSEIREESKTIEEVDETKDNDDDETLEEEGATTVSTERKRKWSEKAWPFLKNVMLQIGIQLGVVLIGILIFQFVSAKFT
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).  Essential protein regulating cell division, adhesion and elongation throughout the plant development and embryogenesis.  Required for the spatial organization of apical meristems.  Involved in the hormonal control of cell division and differentiation mediated by cytokinins and auxin.  Regulates the function of NAC089 transcription factor by controlling its targeting to the nucleus upon plant cell division.  Interacts with enzymes of the fatty acid elongase complex and favors the generation of very-long-chain fatty acids (VLCFAs) required for polar auxin transport and tissue patterning during plant development.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase PASTICCINO1, 70 kDa peptidyl-prolyl isomerase, FK506-binding protein 72, AtFKBP72, Immunophilin FKBP72, Peptidyl-prolyl cis-trans isomerase FKBP72, PPIase FKBP72, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Cytoplasm. Nucleus. Note=Relocalization from the cytoplasm into the nucleus is induced by auxin treatment and in association with NAC089.
Protein: RL27_SYNAS
Sequence: MAHKKGQGSSRNGRDSNAQRRGVKVYGGQSIHAGSIIIRQLGTKIHPGNNVGMGKDYTLFSLIDGVVKFERLDKKRKKVSVYATA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: OFT20_BRANA
Sequence: MALPKNGGNSSSTKKKVSYISVPSQIINSLSSSSLQSLLVSPKKSSRCTNRFSYRNPRIWFLTLFLVSLFGMLKLGLNVDPISLPFSRYPCSTGSFDEHHAVSHLAFASKNDTQSSSSSEHRKNETLPTEGDFWKQPDGLGFKPCLGFSRQYRKDSNSILKNRWKYLLVVVAGGMNQQRNQIVDAVIMARILGASLVVPVLQVNVIWGDESEFADIFDLEHFKNVLADDVHIVSSLPSTHVMTRPAEEKRTPLHASPQWIRAHYLKRINRERVLLLRGLDSRLSNDLPSDLQKLRCKVASQALRFSPRILELGNKLASRMLSEGQYLSLHLRMEKDVWVRTGSLPGLTPEYDEIVNSERQRHPELLTGRSNMTYNERKLAGLCPLTALEVTRLLKALEAPKDARIYWAGGEPLGGKEALEPLTKEFPHLYNKHDLALPGELEPFAKKASVMAAIDYIVCEKSDVFIPSHGGNMGHALQGQRAYAGHKKYITPNKRHMLPYFMNASLPESEFNRIVKDFHRESLGQPELRTGRGGKDVTKHPVSECMCSDRRQQQQ
What is the function of this protein?
May play a role in the biosynthesis of matrix polysaccharides and contribute to the biomechanics and development of the plant cell wall.
What are the official names of this protein?
O-fucosyltransferase 20, O-FucT-20, BnAt2G(1), O-fucosyltransferase family protein.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase GT106 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: BIOB_SHESH
Sequence: MSDIQLRHDWKHDEIEALFALPMNDLLFKAHSLHRQVFDPNEVQISRLLSIKTGACPEDCKYCPQSARYDTGLEKERLIEIEKVLTEARSAKAAGASRFCMGAAWRNPHARDMPYLKDMVSEVKAMGMETCMTLGMLSGTQAEELAEAGLDYYNHNLDTSPEYYGEIITTRTYQDRLDTLSNVRSAGMKVCSGGIVGMGEQASDRAGLLQQLANMEQHPDSVPINMLVKVAGTPFENLDDLDPLEFVRTIAVARIIMPHSRVRLSAGREKMTDEMQAMCFFAGANSIFYGCKLLTTNNPEENEDMTLFKRLGLHPEQGKYATVEDDKEVMAKASAKANAIKDKQSGAFYDAGAL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: RPO11_METM7
Sequence: MNYVNILEKSKNFIELELVNDDHSLSNLIKEVLLSKKGVILASYGVEHPVLDPDTGRYISNPTIMLKTDEKTDAEKVLKEALKDIVDLCNKTLKEL
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo11, DNA-directed RNA polymerase subunit L.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MMPS5_MYCBO
Sequence: MIGTLKRAWIPLLILVVVAIAGFTVQRIRTFFGSEGILVTPKVFADDPEPFDPKVVEYEVSGSGSYVNINYLDLDAKPQRIDGAALPWSLTLKTTAPSAAPNILAQGDGTSITCRITVDGEVKDERTATGVDALTYCFVKSA
What are the official names of this protein?
Probable transport accessory protein MmpS5.
What is the protein family that this protein belongs to?
Belongs to the MmpS family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: K1C17_MOUSE
Sequence: MTTTIRQFTSSSSIKGSSGLGGGSSRTSCRLSGSLGAGSCRLGSASGLGSALGSNSYSSCYSFGTGSGYGGNFGGVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQKQAPGPARDYSAYYHTIEDLKNKILVATVDNASILLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEINVEMDAAPGVDLSRILSEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGKSEISELRRTMQALEIELQSQLSMKASLEGSLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHLTQYKPKEPVTTRQVRTIVEEVQDGKVISSREQVHQTTR
What is the function of this protein?
Type I keratin involved in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair (PubMed:14714564, PubMed:16702408).  Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state (PubMed:16702408).  Modulates the function of TNF-alpha in the specific context of hair cycling.  Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway (PubMed:16710422).  Involved in tissue repair.  May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial 'stem cells'.  Acts as a promoter of epithelial proliferation by acting a regulator of immune response in skin: promotes Th1/Th17-dominated immune environment contributing to the development of basaloid skin tumors (PubMed:20871598).  May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation.
What are the official names of this protein?
Keratin, type I cytoskeletal 17, Cytokeratin-17, CK-17, Keratin-17, K17.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_LEVBA
Sequence: MSAGKIVQVIGPVVDVEFPLNDELPDINTALNIKKDDGSVLVTEVALELGDGVMRTIAMDGTDGLRRGLEVENTGASISVPVGDDTLGRVFNVLGDPIDGGAEFGPDAERMPIHRDAPKYDELNPTTEILETGIKVIDLLEPYVRGGKIGLFGGAGVGKTVLIQELIHNIAQGHNGISVFTGVGERTREGNDMYWEMKGSGVLKQTAMVYGQMNEPPGARMRVALTGLTIAEYFRDVKGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATEMGQLQERITSTKKGSITSIQAVYVPADDYTDPAPATTFAHLDATTNLERALTQQGIYPAVDPLASTSTALAPEIIGQEHYDVATEVQRVLQRYHELQDIISILGMDELSDEEQTIVQRARRIQFFLSQPFSVASQFTGMDGKYVKLEDTIRSFKGILDGKYDDLPEDAFRNCGAIEDAVEKAKQMNDAVANN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MSRA_METTH
Sequence: MMCLSRYEKATFGAGCFWGVEDAFRKVDGVVSTRVGYMGGHLENPTYEDVCTGLTGHAEVVEVTFDPDVVGYSDLLDVFWSIHDPTTLNRQGPDVGEQYRSVIFYHSDEQRRAAIESRRRLEESGRFRDRIVTAIEPAGTFYEAEEYHQQYLEKNPRRRCYLMRLLSTR
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: KCNAE_DROME
Sequence: MPGGRRGLVAPQNTFLENIIRRSNSQPDSSFLLANAQIVDFPIVYCNESFCKISGYNRAEVMQKSCRYVCGFMYGELTDKETVGRLEYTLENQQQDQFEILLYKKNNLQCGCALSQFGKAQTQETPLWLLLQVAPIRNERDLVVLFLLTFRDITALKQPIDSEDTKGVLGLSKFAKLARSVTRSRQFSAHLPTLKDPTKQSNLAHMMSLSADIMPQYRQEAPKTPPHILLHYCAFKAIWDWVILCLTFYTAIMVPYNVAFKNKTSEDVSLLVVDSIVDVIFFIDIVLNFHTTFVGPGGEVVSDPKVIRMNYLKSWFIIDLLSCLPYDVFNAFDRDEDGIGSLFSALKVVRLLRLGRVVRKLDRYLEYGAAMLILLLCFYMLVAHWLACIWYSIGRSDADNGIQYSWLWKLANVTQSPYSYIWSNDTGPELVNGPSRKSMYVTALYFTMTCMTSVGFGNVAAETDNEKVFTICMMIIAALLYATIFGHVTTIIQQMTSATAKYHDMLNNVREFMKLHEVPKALSERVMDYVVSTWAMTKGLDTEKVLNYCPKDMKADICVHLNRKVFNEHPAFRLASDGCLRALAMHFMMSHSAPGDLLYHTGESIDSLCFIVTGSLEVIQDDEVVAILGKGDVFGDQFWKDSAVGQSAANVRALTYCDLHAIKRDKLLEVLDFYSAFANSFARNLVLTYNLRHRLIFRKVADVKREKELAERRKNEPQLPQNQDHLVRKIFSKFRRTPQVQAGSKELVGGSGQSDVEKGDGEVERTKVFPKAPKLQASQATLARQDTIDEGGEVDSSPPSRDSRVVIEGAAVSSATVGPSPPVATTSSAAAGAGVSGGPGSGGTVVAIVTKADRNLALERERQIEMASSRATTSDTYDTGLRETPPTLAQRDLIATVLDMKVDVRLELQRMQQRIGRIEDLLGELVKRLAPGAGSGGNAPDNSSGQTTPGDEICAGCGAGGGGTPTTQAPPTSAVTSPVDTVITISSPGASGSGSGTGAGAGSAVAGAGGAGLLNPGATVVSSAGGNGLGPLMLKKRRSKSRKAPAPPKQTLASTAGTATAAPAGVAGSGMTSSAPASADQQQQHQSTADQSPTTPGAELLHLRLLEEDFTAAQLPSTSSGGAGGGGGSGSGATPTTPPPTTAGGSGSGTPTSTTATTTPTGSGTATRGKLDFL
What is the function of this protein?
Structural component of a potassium channel.  Mediates the potassium permeability of membranes; potassium current is regulated by CaMKII and CASK.  Has a role in growth of the perineurial glial layer of the larval peripheral nerve.
What are the official names of this protein?
Potassium voltage-gated channel protein eag, Ether-a-go-go protein.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Eag sub-subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Note=Eag recruits CASK to the plasma membrane.
Protein: RPOZ_PROMP
Sequence: MNVSNNSNMDHNDLAKRGESLIRKSTNRYLTTVRIAFRAKQRRFDDFDGLLEESAIKPVQRSIIELSDEQDQPDLLPG
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: PTLH_BORPA
Sequence: MNDAAPDRQASVDFHLQALHPWLSRQDIAEICVNRPGQLWYEDRNGWNRQESGALTLDHLHALATATARFCDRDICPERPLLAASLPGGERVQIVVPPACEPGTLSLTIRKPARRIWPLSELLRDTLDLPGVPGASQARPDPLLDPWRRGAWDDFLRLAVQAGKAILVAGQTGSGKTTLMNALSGEIPPRERIVTIEDVRELRLDPATNHVHLLYGTPTEGRTAAVSATELLRAALRMAPTRILLAELRGGEAFDFLQACASGHSGGISTCHAASADMALQRLTLMCMQHPNCQMLPYSTLRALVESVIDIVVVVERRAGQGARRRVVDIWYRDGLPAP
What are the official names of this protein?
Type IV secretion system protein PtlH homolog.
What is the protein family that this protein belongs to?
Belongs to the GSP E family.
Protein: YD286_HUMAN
Sequence: MLWFQGNSMQLARSSFGLFLRNCSASKTTLPVLTLFTKDPCPLCDEAKEVLKPYENRQPYKDQKLPGTRRRRSPSSPSHPHMASQSGKRYNLTLNQVLSFDYDMGLDAPKTISSDCGAFYCLRMFKSPDMTCCFYPKQ
What are the official names of this protein?
Glutaredoxin-like protein C5orf63.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family. YDR286C subfamily.
Protein: PPNP_SALEP
Sequence: MLQSNEYFSGKVKSIGFTSSSTGRASVGVMAEGEYTFGTAEPEEMTVVSGALKVLLPGTVEWKVYTAGEVFNVPGHSEFHLQVAEPTSYLCRYL
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: K1C10_CANLF
Sequence: MSVRYSSSKQYSSSRSGGGGGGGGGSSFRISSSKGSIGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYGGLGGGFGGGNFGGGYGSSSFGGGYGGVSFGGGSFGGGSFGGGGFSGGSFGGYGGGYGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHGNSSQRAPRDYSKYYQTIEDLKNQILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMRDLQNVSTGDVNVEMNAAPGVDLTELLNNMRNQYEQLAEQNRKDAEAWFNEKSKELTTEINSNIEQMSSHKSEITELRRTVQGLEIELQSQLALKQSLEGSLAETEGRYCVQLSQIQAQISSLEEQLQQIRAETECQNAEYQQLLDIKIRLENEIQTYRSLLEGEGSSGGGGYGGGRGGGSSGGGYGGSSGGGYGGSSGGGGYGGGSSGGGGHIGGHSGGHSGSSGGGYGGGSSSGGGGYGGGSSGGGGSHGGSSGGGYGGGSSSSGGHKSSSSGSVGESSSKGPRY
What is the function of this protein?
Plays a role in the establishment of the epidermal barrier on plantar skin (By similarity).  Involved in the maintenance of cell layer development and keratin filament bundles in suprabasal cells of the epithelium (By similarity).
What are the official names of this protein?
Keratin, type I cytoskeletal 10, Cytokeratin-10, CK-10, Epithelial keratin-10, Keratin-10, K10.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Secreted, extracellular space. Cell surface. Cytoplasm.
Protein: QUEC_AGRFC
Sequence: MKTIVICSGGLDSVSLAHKIAAEHELLALVSFDYGQRHKKELDFAADCAKRLGVPHHLIDIGTIGAHLTGSALTDDIDVPDGHYAEETMRSTVVPNRNAIMLTIAFGLAAAQQADAVAIAVHGGDHFIYPDCRPGFIGSFNAMQAHALEGYADVTLFAPYVTVSKAAIVTDAVKYGTPFGETWSCYKGGLRHCGRCGTCVERREAFHLAGVTDPTEYEDPDFWVAATQAYAAQEVH
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: RS11_CHLP8
Sequence: MATASRKKKKVKVTPEGTVHIKASFNNIMVTITDTLGNTVSWSSAGKNGFRGSKKNTPYASQVTSEAAAKEAYDLGMRYVDVLIKGPGSGRDAAIRALQGVGLEVRSIRDITPLPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: AROE_ACIBS
Sequence: MTKQFAVIGNPIEQSRSPELHHAFAEKTGVDLNYQKRLAPLDGFESSMRSFFAEGGSGMNVTVPFKEQAFALCNVLTERAQIAKAVNTLWMENGKLHGDNTDGQGLVAAIQALEWNLENTTILILGAGGATRGVIYPLVQAGAKKIVIANRTLARAEQLVDDLKTAVPQAQLQAISLNDLEGDFDIVINATSASLSGDALQLPEKLKFKYAYEMAYGKPSSFLDQAKQRNVPYAEGFGMLVGQAIEAFSIWNGVRPQLKDFL
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: ZN394_HUMAN
Sequence: MNSSLTAQRRGSDAELGPWVMAARSKDAAPSQRDGLLPVKVEEDSPGSWEPNYPAASPDPETSRLHFRQLRYQEVAGPEEALSRLRELCRRWLRPELLSKEQILELLVLEQFLTILPEELQAWVREHCPESGEEAVAVVRALQRALDGTSSQGMVTFEDTAVSLTWEEWERLDPARRDFCRESAQKDSGSTVPPSLESRVENKELIPMQQILEEAEPQGQLQEAFQGKRPLFSKCGSTHEDRVEKQSGDPLPLKLENSPEAEGLNSISDVNKNGSIEGEDSKNNELQNSARCSNLVLCQHIPKAERPTDSEEHGNKCKQSFHMVTWHVLKPHKSDSGDSFHHSSLFETQRQLHEERPYKCGNCGKSFKQRSDLFRHQRIHTGEKPYGCQECGKSFSQSAALTKHQRTHTGEKPYTCLKCGERFRQNSHLNRHQSTHSRDKHFKCEECGETCHISNLFRHQRLHKGERPYKCEECEKSFKQRSDLFKHHRIHTGEKPYGCSVCGKRFNQSATLIKHQRIHTGEKPYKCLECGERFRQSTHLIRHQRIHQNKVLSAGRGGSRL
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 394, Zinc finger protein with KRAB and SCAN domains 14.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TMCAL_AGARV
Sequence: MKVAGVITEYNPFHNGHKYQLEQIKRQTSADYIVVVMSGDFVQRGEPAIIDKYERTRMALLSGADLVLELPSVFATASAEFFAGGGVSVLKNTGVVDMLCYGVESVDHELTKLVAGVLKNPPSEYSASLARLIQGGMSFPAARSRALCEYFRDTYDSASEKLDAFIASPNNILAIEYEKALMDCDITGFPIQRVGEGYHSTDSTSEFSSATAVRGVISTLIDIDKHNTITNMQLDNSWISTKFSQLIPSACADILVNCILGGHIVFPDDISEMLYYRLLTGKDKGFAQYADCTKELSAKIVKNIYKYEGFTQFCNLLKSKNLTYTRISRVLTHILLGIENNDFNICMNNPYLRILGFKKSSGELMHLLKKRASVPIITKVADAPYELISKDIFAADLYGRLCHSQQNEFTHGVVII
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_DESHD
Sequence: MKVILKADVKALGKKGQVYEVSDGYARNFLFPKGLAVEATSGNLNDLASKKANEEKKKEQEKQEAQTLAAKLSSLSIEIHTKSGEGGRLFGSVTNKEIAEALKASHGINLDRRKLELKEPIKALGTFNVQAKLHPEVTAQFQVHVKAS
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: ERIC4_RAT
Sequence: MELWAQLKQAGLESSGLGPLPQALRMPPPEGNPGQALMSSGAEFGGARELLLWIWEELGNLRRVDVQLLGQLCDLGLEMGTLREELVTILEEEEEDDDEEEQEEEGEGKNCVEENKGLQGKQGEKCSGNPYPAQRLPDFEMTI
What are the official names of this protein?
Glutamate-rich protein 4.
Protein: TATA_RALPJ
Sequence: MGSFSIWHWLIVLVIIMMVFGTKKLRNIGSDLGSAVKGFKDGMREGQEDKPAGSQQPQQTAGQPPRELHDATTIDVEARDKSKQG
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.