PharMolix/UniProtQA huggingface dataset:
Protein: ATP6_PROMP
Sequence: MFLNSLPTNFAALEVGQHLYWQIGNIRLHGQVFLTSWILLGALLVFISVGTKKMENDPKGLQNLLEFLWDYIRDLSRTQIGEKVYRDWMPFIGTLFLFVFVSNWGGALIPWRLIKLPSGELGAPTADINTTIALALLVSLSYFYAGLSNKGWRYFEYYVHPTPIMLPFKILEDFTKPLSLSFRLFGNILADELVVGVLVFLVPLVLPIPVMFLGLFTSAIQALIFATLAAYYIGEAVEEHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: RS7_ECOLI
Sequence: MPRRRVIGQRKILPDPKFGSELLAKFVNILMVDGKKSTAESIVYSALETLAQRSGKSELEAFEVALENVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALAMRWIVEAARKRGDKSMALRLANELSDAAENKGTAVKKREDVHRMAEANKAFAHYRWLSLRSFSHQAGASSKQPALGYLN
What is the function of this protein?
Protein S7 is also a translational repressor protein; it regulates the expression of the str operon members to different degrees by binding to its mRNA.
What are the official names of this protein?
30S ribosomal protein S7, Small ribosomal subunit protein uS7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: ATG13_KLUMD
Sequence: MSDSDREIIGLINNFFLKAALLLEQCKVVARGGGFDGEEPLRDGNHLFNIETRGDPTLEAQIQPWTTFDGEKSMPPLVLETFLDLRGLHSNQTVYLHDSDGNPWMVCKGGKKSEIVLERWLIELDRQFSSTTGSTDAAEDDEYNEFNDPENLHKQLVLLFRYLYTLTQLLPANDIITKLQASQQGTAQATTTTGTLKPLHIHTRLLDGSKPILSKGRVGLSKPIIASYSNTMNETNIASHLEQRKITPIKTKFGSLRITVSYRKDVDFYVIDQEDPYKRTTNVSALQDTVTATDRRISSNSNISISVSPKTTNMLNANHIPVDSSGGGFARRQSISSKLQPFKVGSVGSGSFVQSGSLQSVTNPNPSLSRNVSSSSVAAALKVQRGSAGSTVLNSDLPPELSSVGSGSKYSSSFGRIRRHSSVRRSESIDRTAKPRKSNETPPEDLLEFVKLLEDKKELNMKPSTILPQQDISSSLIKFQSMKPNNDTLSDNLSMSMSIDQPNMRMGSNSHSPIPSFSPNYGSIPSRLSQGSRNNSNVELITSRKSSLDRHRLSLLNRTGSNVDIRRGSVGTMETTNEDSKEDEDSHVHGLRFNSGTVNDKTEDNNEDDDEEEILIKRSSNAVASSTEHFSVSPRSARSISVSSYTRSQLPLKHPNFSYPTTSATTAHAKFHKSEVIPDQLHREGSHHHNSSHKNDEDDDLLFVMSDMNLTN
What is the function of this protein?
Activates the ATG1 kinase in a nutritional condition dependent manner through the TOR pathway, leading to autophagy (PubMed:26442587, PubMed:24793651).  Involved in ATG9 and ATG23 cycling through the pre-autophagosomal structure (By similarity).  Also involved in cytoplasm to vacuole transport (Cvt) and more specifically in Cvt vesicle formation (PubMed:24793651).  Seems to play a role in the switching machinery regulating the conversion between the Cvt pathway and autophagy (By similarity).  Finally, ATG13 is also required for glycogen storage during stationary phase (By similarity).
What are the official names of this protein?
Autophagy-related protein 13.
What is the protein family that this protein belongs to?
Belongs to the ATG13 family. Fungi subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure.
Protein: SMVA_SALT1
Sequence: MFRQWLTLVIIVLVYIPVAIDATVLHVAAPTLSMTLGASGNELLWIIDIYSLVMAGMVLPMGALGDRIGFKRLLMLGGTLFGLASLAAAFSHTASWLIATRVLLAIGAAMIVPATLAGIRATFCEEKHRNMALGVWAAVGSGGAAFGPLIGGILLEHFYWGSVFLINVPIVLVVMGLTARYVPRQAGRRDQPLNLGHAVMLIIAILLLVYSAKTALKGHLSLWVISFTLLTGALLLGLFIRTQLATSRPMIDMRLFTHRIILSGVVMAMTAMITLVGFELLMAQELQFVHGLSPYEAGVFMLPVMVASGFSGPIAGVLVSRLGLRLVATGGMALSALSFYGLAMTDFSTQQWQAWGLMALLGFSAASALLASTSAIMAAAPAEKAAAAGAIETMAYELGAGLGIAIFGLLLSRSFSASIRLPAGLEAQEIARASSSMGEAVQLANSLPPTQGQAILDAARHAFIWSHSVALSSAGSMLLLLAVGMWFSLAKAQRR
What is the function of this protein?
Major efflux pump for acriflavine and other quaternary ammonium compounds (QACs).  Also required for resistance to methyl viologen.
What are the official names of this protein?
Methyl viologen resistance protein SmvA.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ESAB_STAAE
Sequence: MNQHVKVTFDFTNYNYGTYDLAVPAYLPIKNLIALVLDSLDISIFDVNTQIKVMTKGQLLVENDRLIDYQIADGDILKLL
What is the function of this protein?
Seems to regulate secreted factors that contribute to the establishment of persistent infections in the host.  Negative regulator of EsxC.  Not necessary for the production and secretion of EsxA or EsxB.
What are the official names of this protein?
Type VII secretion system accessory factor EsaB.
What is the protein family that this protein belongs to?
Belongs to the EsaB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TDCC_SHIB3
Sequence: MSTSDSIVSSQTKQSSWRKSDTTWTLGLFGTAIGAGVLFFPIRAGFGGLIPILLMLVLAYPIAFYCHRALARLCLSGSNPSGNITETVEEHFGKTGGVVITFLYFFAICPLLWIYGVTITNTFMTFWENQLGFAPLNRGFVALFLLLLMAFVIWFGKDLMVKVMSYLVWPFIASLVLISLSLIPYWNSAVIDQVDLGSLSLTGHDGILITVWLGISIMVFSFNFSPIVSSFVVSKREEYEKDFGRDFTERKCSQIISRASMLMVAVVMFFAFSCLFTLSPANMAEAKAQNIPVLSYLANHFASMTGTKTTFAITLEYAASIIALVAIFKSFFGHYLGTLEGLNGLILKFGYKGDKTKVSLGKLNTISMIFIMGSTWVVAYANPNILDLIEAMGAPIIASLLCLLPMYAIRKAPSLAKYRGRLDNVFVTVIGLLTILNIVYKLF
What is the function of this protein?
Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system).
What are the official names of this protein?
Threonine/serine transporter TdcC, H(+)/threonine-serine symporter.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PROA_NOVAD
Sequence: MSTQPATIADSATDLVEGLARAARSAQRQLARMDSPVKERALTLAAAALRAAEAEILAANAQDMANGAANGLSSAMLDRLKLTPERLAGIADAVAQVAGLADPVGEVISEAARPNGMVLQRVRIPVGVIGIIYESRPNVTADAAALCVRSGNAAILRGGSEAVHSNRAIHKALVAGLAEGGVPAEAVQLVPTQDRAAVGAMLGAAGLIDMIVPRGGKSLVARVQADARVPVLAHLDGINHTFVHASADPAMAQAIVLNAKMRRTGVCGAMETLLIDATYPDPHGLVEPLLDAGCELRGDARARAIDPRIAPAADNDWDTEYLEAILSVAVVDGLDEALAHIARHASGHTDAIVAADQDVADRFLAEVDSAIVMHNASSQFADGGEFGLGAEIGIATGRLHARGPVALEGLTTYKWLVRGSGQTRP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y139_MYCPN
Sequence: MKEKIPFYNEKEFHDMVKKTKKGTFSGWYIINKNNNSVEFSGSFNRQFKLNKPVIPVNTEYVTRKEFNEYKDSNDQRLTKIETELKSQGQRIQVVEDKVDRLTEVVMVQSQQIKTQGEAMNARMDRFESLVLKSLESIGNTLTDFGKRLDVIETRLDKIDPPK
What are the official names of this protein?
UPF0134 protein MPN_139.
What is the protein family that this protein belongs to?
Belongs to the UPF0134 family.
Protein: CYB6_HELGE
Sequence: MKWLEERFPGIGHVAKDVADHPVPSHTLNIFFCLGGLTLLCFIVQCLTGIFLAFYYKPTPEAAFTSVQMITNEVRFGSVIRSMHHWSCQLMILLVFLHMLRVYYTGAFKRPRELNWVAGCFLLVLSLALAFTGYLLPYEQLSYWASVIGAETANTLPVVGPTLKIMMQGGIKVTAEMLSRFYVLHVMILPAVAIIFLVAHFIMIRVQGISDPM
What is the function of this protein?
Component of the cytochrome bc complex which donates electrons to the photosynthetic reaction center.
What are the official names of this protein?
Cytochrome b6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CUTI1_COLKA
Sequence: VIYIFAR
What is the function of this protein?
Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants (PubMed:17043825).  Degrades cutin, a macromolecule that forms the structure of the plant cuticle (PubMed:17043825).  Allows pathogenic fungi to penetrate through the cuticular barrier into the host plant during the initial stage of fungal infection (By similarity).
What are the official names of this protein?
Cutinase 1, Cutin hydrolase 1.
What is the protein family that this protein belongs to?
Belongs to the cutinase family.
What are the subcellular locations of this protein?
Secreted.
Protein: CIA30_CAEBR
Sequence: MISNFTGRLLLPKFRNKLCAFFSKESTSSNSLAKSKTNSELEGYTGKSNLLEKKKVGVFGTSTVPINTNFPNPKGVIGYDPDFSVKELVAELPNTRKTQGAKLAEEIKDAFSNISIEKPELLEDIGFVRHNEARVEYKFDTSEKLDLWKIGCDSDWKEGFSTCSLVNSDRGTAVFSGNISTRVLKDGRVERAGWASMKLEDRKTFNRKKFLSKWRNFSHLLLKVRGDGRSYKIMLHSPLSMDFTWGDSFSHPLHTHGGPYWQYEKIPFSKFFHTVAGRIQDRQYRVNLEDTSSIGIVLMDRIDGDFKLEIDYIGVYNDTTHVEDFAYETYTLPVFNTHGF
What is the function of this protein?
Chaperone protein involved in the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).  Required for normal growth and reproduction (By similarity).
What are the official names of this protein?
Probable complex I intermediate-associated protein 30, mitochondrial, NADH ubiquinone oxidoreductase assembly factor 1.
What is the protein family that this protein belongs to?
Belongs to the CIA30 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ATPA_AZOC5
Sequence: MDIRAAEISAILKEQIQNFGREAEVSEVGQVLSVGDGIARVYGLDNVQAGEMVEFENGTRGMALNLEIDNVGVVIFGSDRDIKEGQTVKRTGAIVDVPVGRGLLGRVVDALGNPIDGKGPIEATERRRVDVKAPGIIPRKSVHEPMQTGLKAIDALIPIGRGQRELIIGDRQTGKTAVALDAILNQKPLNVAGAPESQKLYCVYVAVGQKRSTVAQFVKVLEEQGALEYSIVVAATASDPAPMQFLAPFAGTAMGEYFRDNGMHALIIHDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDENGAGSLTALPVIETQANDVSAYIPTNVISITDGQIFLESDLFYQGIRPAVNVGLSVSRVGSSAQIKAMKQVAGKIKGELAQYRELAAFAQFGSDLDASTQKLLNRGARLTELLKQSQFSPLKVEEQVVVIYAGTNGYLDNLPLNKVREFEAGFLLAMRTQHQDLLDTIRTSKELSKDSIANLTKALDAFAKSFA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GUN1_STRSS
Sequence: MENPRTTPTPTPLRRRRSERRARGGRVLTALTGVTLLAGLAIAPAATGASPSPAPPASPAPSADSGTADAGTTALPSMELYRAEAGVHAWLDANPGDHRAPLIAERIGSQPQAVWFAGAYNPGTITQQVAEVTSAAAAAGQLPVVVPYMIPFRDCGNHSGGGAPSFAAYAEWSGLFAAGLGSEPVVVVLEPDAIPLIDCLDNQQRAERLAALAGLAEAVTDANPEARVYYDVGHSAWHAPAAIAPTLVEAGILEHGAGIATNISNYRTTTDETAYASAVIAELGGGLGAVVDTSRNGNGPLGSEWCDPPGRLVGNNPTVNPGVPGVDAFLWIKLPGELDGCDGPVGSFSPAKAYELAGG
What is the function of this protein?
CMCase I preferentially hydrolyzes carboxymethyl cellulose (CMC).
What are the official names of this protein?
Endoglucanase 1, CMCase I, Carboxymethyl cellulase, Cellulase, Endo-1,4-beta-glucanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 6 (cellulase B) family.
Protein: LIPB_PROM9
Sequence: MVNRTAIIKQPDNISCFNDVYKLQKEYQEALILDNSNPDFIWIGEHQLCYTLGRGSNYDNLLFSLNDEKYDVFKIDRGGEVTCHMPGQLVTYLILDLKNFNKDLNWYLRKIEKIIIKILGNFNIDCHLKKGFTGVWIENKKIASIGIGCRRWITINGFSINFNCELENFNKIVPCGIENCLMANMIDYNKNLNIKEVKKIVKKIIQEEFNFDFVSK
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BSPRY_HUMAN
Sequence: MSAEGAEPGPGSGSGPGPGPLCPEHGQALSWFCGSERRPVCAACAGLGGRCRGHRIRRAEERAEELRNKIVDQCERLQLQSAAITKYVADVLPGKNQRAVSMASAARELVIQRLSLVRSLCESEEQRLLEQVHGEEERAHQSILTQRVHWAEALQKLDTIRTGLVGMLTHLDDLQLIQKEQEIFERTEEAEGILDPQESEMLNFNEKCTRSPLLTQLWATAVLGSLSGTEDIRIDERTVSPFLQLSDDRKTLTFSTKKSKACADGPERFDHWPNALAATSFQNGLHAWMVNVQNSCAYKVGVASGHLPRKGSGSDCRLGHNAFSWVFSRYDQEFRFSHNGQHEPLGLLRGPAQLGVVLDLQVQELLFYEPASGTVLCAHHVSFPGPLFPVFAVADQTISIVR
What is the function of this protein?
May regulate epithelial calcium transport by inhibiting TRPV5 activity.
What are the official names of this protein?
B box and SPRY domain-containing protein.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: SYG1_SCHPO
Sequence: MKFGKVIEGQSVAEWASAYFDYKKGKKIIAGIAKNPSEGLYGTSGILGETPEEAIVKRGQIHRFHPLFQEFLDQQANKVEEFFENLVSDARERMDLISDQVDIYEKLRAFKKGTLESGSVVLIQKQHSKLRQRLDSILNFSRLQPAYHIPARKSVPTDAYTPMVSYRKLKSKLKTTLLDFYDYLKLVSQYQHLNQQAFRKIVKKYDKTLHTDLQGFWVDYMSRYTFTDFSITTNWQLHVEDIYARLFTNHNKKLALEHLKSFRQKEHFSANSMRFGLLFGAGLPLAIEAACYYNATEQSSYLLQIWGGFFLVIFAFVLFDLDCYVWEKTRVNYMLIFEFNQRKSLNWRQHLEIVGAVFFIFSLFFFLCMRNFFPGFTIYFPALFLGVVGTFLIAPVIVPYWRMRRYLIIQLIRVFLSGLSTVHFQDFFFADQMVSLTYACGNISLFFCLYKRLWRQPQLCNSSHSPLLGFFTTLPGILRVFQCFRRYSDSLKSFPHLVNALKYIFNILAQMFLSLWRIHPGLKYRVLYTIFAGVNSLFSYTWDILMDWNLLVRKDGRWQFREHRILKQLWPYIIAMILNFIVRSSFIFYCIFPNHIQHSSGISFFVTLAEIMRRCMWNILRVEHEEIYNRENLRAARELKPLDFVKPHSDVFVSHQISSDKNYTDDEDSMDDQTDVDEAQFS
What is the function of this protein?
May function in G-protein coupled signal transduction.
What are the official names of this protein?
Protein SYG1 homolog.
What is the protein family that this protein belongs to?
Belongs to the SYG1 (TC 2.A.94) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RK16_PLETE
Sequence: MLSPKRTKYRKHHRGRMKGKATRGNKIVFGDFALQALEPAWITSRQIEAGRRAMTRYARRGGKLWIRIFPDKPVTMRPAESRMGSGKGSPEYWVAVVKPGKILYEMKGVSEIIARAAMRIASYKMPIKTNFLVKSTSPN
What are the official names of this protein?
50S ribosomal protein L16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PUR4_PHOPR
Sequence: MEILRGSPALSEFRVNKLLERCRELDLPVSGIYAEFMHFADVSAPLNSDEQSKLASLLTYGPTIAEHEPTGTMLLVTPRPGTISPWSSKSTDIAQNCALGNVKRLERGTAYYVEVTADLTNAQLTDLKALIHDRMMEVVFTDVDSAAALFTQAEPAPVQSVDILVGGRKALEDANLKLGLALAEDEIDYLVENFTMLGRNPNDIELMMFAQANSEHCRHKIFNADWTIDGVEQEKSLFKMIKNTYEKNHEHVLSAYKDNAAVMEGSEVGRFFPNPESRQYNYHQEAAHILMKVETHNHPTAISPWPGASTGSGGEIRDEGATGLGGKPKAGLVGFTVSNLRVPGFEQPWETDFGKPGRIVNALEIMLEGPLGGAAFNNEFGRPNLLGYFRTYEEKVTSHNGEEIRGYHKPIMIAGGMGNIRADHVQKKEIPVGAKLIVLGGPAMNIGLGGGAASSMASGQSAEDLDFASVQRENPEMERRCQEVIDRCWQMGDANPIAFIHDVGAGGISNALPELVDDGERGGKFQLRNVPNDEPGMSPLEIWCNESQERYVMAVAPENLAVFEAICKRERAPFAVVGEATEERHLTLEDEHFDNTPIDMPMDILLGKAPKMHRDAKTLKVEGQAIDRSGIELEAATQRVLRLPAVAEKTFLITIGDRSVTGLVARDQMVGPWQVPVANCAVTAASYDTYHGEAMSMGERTPVALLDFGASARLAVGEAITNIASADIGDMKRINLSANWMSPAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMSMKTKWEQDGEQKEVTSPLSLVITAFGRVEDVRKTVTPQLRTDKGESSLILIDLGCGQNRLGATALAQVYKQLGDKPADVDNPELLKGFFYAVQALVRDEKVLAYHDRGDGGLYVTLAEMAFAGHTGVEVDINTSESDACDDVLAMLFNEELGAVLQVRTEDLDTVKSVLAEHGLTACSHVIGTVVDEDVVRIWNGNDRVLEQSRTDLRTVWAETTYQMQAMRDNPAGALQEFEAKKDNSDPGLSAQLTFDINEDVAAPFIAAPFITKAPKTGASVVNAPAINLGAKPQMAILREQGVNSHVEMAAAFDRAGFEATDVHMSDILSGNVQLEGFNGLVACGGFSYGDVLGAGEGWAKSVLFNNIARDQFEAFFKRNDTFSLGVCNGCQMMSNLSELIPGSDLWPRFVRNESERFEARFSLVEVQKSDSLFFNEMAGSRMPIAVSHGEGRVEVRNGEHLNAIEQSGTVALRYLDNFGNVTQNYPANPNGSPNGITGLTTMDGRVTIMMPHPERVFRTVANSWHPDDWNENSPWMRMFRNARVNLG
What is the function of this protein?
Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase, FGAM synthase, FGAMS, Formylglycinamide ribonucleotide amidotransferase, FGAR amidotransferase, FGAR-AT.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH10_STRP1
Sequence: MLKPLGDRVVVRFDDEKEQTVGGFVLAGTHKESTRKATVLAVSETGVRTITGDSVLPSVSVGQEVLVENGHDLEVTVDDEKVSIIRESDIIAIVTK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_METM5
Sequence: MQKARIKLSSTQHTELDGVCNQIKAIAEKTGVDMAGPIPLPTKALKVTTRKSTDGEGSSSFDRWTMRVHKRVIDIEADERTMKHIMKVRIPDTVQIEIELRN
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: HTPX_ECO24
Sequence: MMRIALFLLTNLAVMVVFGLVLSLTGIQSSSVQGLMIMALLFGFGGSFVSLLMSKWMALRSVGGEVIEQPRNERERWLVNTVATQARQAGIAMPQVAIYHAPDINAFATGARRDASLVAVSTGLLQNMSPDEAEAVIAHEISHIANGDMVTMTLIQGVVNTFVIFISRILAQLAAGFMGGNRDEGEESNGNPLIYFAVATVLELVFGILASIITMWFSRHREFHADAGSAKLVGREKMIAALQRLKTSYEPQEATSMMAFCINGKSKSLSELFMTHPPLDKRIEALRTGEYLK
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CGOX_PROFF
Sequence: MSTTDRVTTPTPTVSGTDAPGPDASHCHLVVVGGGITGLAAAWQGMARGARVSVVESDDHFGGKVVTDRRDGFLVEQGPDSFVAYRPAALKLIEELGLSDQVIAPGGGRRVSLLSRGKLRPMPAGMGMVLPTRMWPFVTTTVLSWPDKIRAGLDLVIPRRLPDHDVAIGAFLRQRLGDGIVRRFADPMVGGIYGAGIDELSLDAVLPSLRDNERDHRSLMVASLAGGRASRRAARQRAAQNNAQQNSSHQNSTGQNNSAGTRGPAASPFRTLRGGLGQLIDALVDQLRAGGVELLVNTSVDLLGRDGVHLSDGRVLPADAVVLAGGVASSARLLRPQLPAAARALAQIPLASTTIVSLAWPVSAFDVAPDSQGWLEADAGPVSGLTASSIKFAGRAPDGSVLMRVFVPDKRGPLTDAPDDELLSAVIDHVRPLLGVHGEPGLTQITRWHKVMPKYTVGHLERAAVVDSTLAEQRPTWAVAGSALHGVGLPDCISDARHSADEVIDAALAATPSAPNRNAATDRTETR
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.
What are the official names of this protein?
Coproporphyrinogen III oxidase.
What is the protein family that this protein belongs to?
Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROA_SHEHH
Sequence: MNQLRLEPIKKVSGTINIPGSKSISNRALLLATLASGTTTLTNLLDSDDIRYMLASLKQLGVSYRLSNNNTVCELDGLAGPLNAGEPQTLFLGNAGTAMRPLCAALTLGQGQFTLTGEPRMEERPIGDLVDALRQLGAEVSYLKNEGFPPLNITSTGLNGGNVEIAGDLSSQFLTALLMVAPLAKGDVNIKIKGELVSKPYIDITLALMAQFGVEVQNNDYASFVIKAGQRYVSPGKVLVEGDASSASYFLAAGAIQGGEVKVTGVGKLSIQGDVKFADVLEQMGADIEWGDDYIIARQAKLKAVDLDMNHIPDAAMTIATAALFATGTTRIRNIYNWRIKETDRLAAMATELRKVGAIVDEGHDYISVTPPAKLNTAAIDTYNDHRMAMCFSMMAFADCGITINEPECTSKTFPDYFNQFNALAN
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTH_BORA1
Sequence: MHAQGFLCSKHAMSEPIRLIVGLGNPGPDYETTRHNAGFWLADRLADDLRATFALEKGFMGMVAKARFEGENVLLLKPITYMNRSGQAVGALARFYKLAPEQVLVLHDELDLLPGQVKMKQGGGHAGHNGLKDIQAALGTPNFWRLRLGIGHPRTLNLAQQVADFVLHPPRRDEQAEIDTVIDRCRAVVPALLRGDFAQATRQLHTA
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CEMA_CITSI
Sequence: MTKKNASIPLRYLSSIVFVVFLPWWIPLSFNKSLESWVTNWWNTSQSETFLNDIQEKAILEKFIELEELFLLDEMIKEFPERRLEKLRIGLQKETIQLIKMHDEDHIHTIFHFSTNTICFVILSGYSILCNEELFILNSWVQEFLYNLSDTIKAFSILFVTDLCIGFHSPRGWELLIGYVYNDFGLAHNDNDIILSVLVSTFPVVLDTFFKYWLFSYLNRVSPSLVVIYHSMTE
What is the function of this protein?
May be involved in proton extrusion.  Indirectly promotes efficient inorganic carbon uptake into chloroplasts.
What are the official names of this protein?
Chloroplast envelope membrane protein.
What is the protein family that this protein belongs to?
Belongs to the Cema family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: RS10_FRATW
Sequence: MAINNQRIRIRLKAFDHKLIDISTQEIVDTAKKTGAQVKGPIPLPVRKERFTILISPHVNKKARDQYEIRTHKRLIDIVEPTDKTVDALMKLDLASGVDVQISLS
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: DUSTY_HUMAN
Sequence: MEGDGVPWGSEPVSGPGPGGGGMIRELCRGFGRYRRYLGRLRQNLRETQKFFRDIKCSHNHTCLSSLTGGGGAERGPAGDVAETGLQAGQLSCISFPPKEEKYLQQIVDCLPCILILGQDCNVKCQLLNLLLGVQVLPTTKLGSEESCKLRRLRFTYGTQTRVSLALPGQYELVHTLVAHQGNWETIPEEDLEVQENNEDAAHVLAELEVTMHHALLQEVDVVVAPCQGLRPTVDVLGDLVNDFLPVITYALHKDELSERDEQELQEIRKYFSFPVFFFKVPKLGSEIIDSSTRRMESERSPLYRQLIDLGYLSSSHWNCGAPGQDTKAQSMLVEQSEKLRHLSTFSHQVLQTRLVDAAKALNLVHCHCLDIFINQAFDMQRDLQITPKRLEYTRKKENELYESLMNIANRKQEEMKDMIVETLNTMKEELLDDATNMEFKDVIVPENGEPVGTREIKCCIRQIQELIISRLNQAVANKLISSVDYLRESFVGTLERCLQSLEKSQDVSVHITSNYLKQILNAAYHVEVTFHSGSSVTRMLWEQIKQIIQRITWVSPPAITLEWKRKVAQEAIESLSASKLAKSICSQFRTRLNSSHEAFAASLRQLEAGHSGRLEKTEDLWLRVRKDHAPRLARLSLESCSLQDVLLHRKPKLGQELGRGQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLPKHERLVDLHGSVIDYNYGGGSSIAVLLIMERLHRDLYTGLKAGLTLETRLQIALDVVEGIRFLHSQGLVHRDIKLKNVLLDKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELFTGKYDNSVDVYAFGILFWYICSGSVKLPEAFERCASKDHLWNNVRRGARPERLPVFDEECWQLMEACWDGDPLKRPLLGIVQPMLQGIMNRLCKSNSEQPNRGLDDST
What is the function of this protein?
Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation (PubMed:23862974, PubMed:28157540).  Involved in the regulation of both caspase-dependent apoptosis and caspase-independent cell death (PubMed:15178406).  In the skin, it plays a predominant role in suppressing caspase-dependent apoptosis in response to UV stress in a range of dermal cell types (PubMed:28157540).
What are the official names of this protein?
Dual serine/threonine and tyrosine protein kinase, Dusty protein kinase, Dusty PK, RIP-homologous kinase, Receptor-interacting serine/threonine-protein kinase 5, Sugen kinase 496, SgK496.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Apical cell membrane. Basolateral cell membrane. Cell junction. Note=Detected at apical cell-cell junctions. Colocalized with FGF receptors to the cell membrane (By similarity). Detected in basolateral and apical membranes of all tubular epithelia.
Protein: FAU_DROME
Sequence: MVYESGFTTRRTYSSRPVTTSYAVTTPRLDLCTDRPGSHRSRASSDYSYTSKSSVEKSSYDSSNPHSYRPERSTYTSTVEKTSRSGPGGSYNYSTERTSTTGAGPGGYSYSSTTSGNLPGGTKYRHFSYHV
What is the function of this protein?
Plays an important role in the regulation of tissue responsiveness to oxygen deprivation.
What are the official names of this protein?
Protein anoxia up-regulated.