PharMolix/UniProtQA huggingface dataset:
Protein: GCSH_SHEON
Sequence: MSNIPTELKYASSHEWIRKEEDGSYTVGITEHAQELLGDMVFVELPEVGDTVTAGDDCAVAESVKAASDIYAPISGEVIAVNEALEDSPELVNSDAYGEGWFFRVMPSDESEVDALLDAEGYQAVIDEE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: HOLB_PSEAE
Sequence: MADIYPWQQALWSQLGGRAQHAHAYLLYGPAGIGKRALAEHWAAQLLCQRPAAAGACGECKACQLLAAGTHPDYFVLEPEEAEKPIRVDQVRDLVGFVVQTAQLGGRKVVLLEPAEAMNVNAANALLKSLEEPSGDTVLLLISHQPSRLLPTIKSRCVQQACPLPGAAASLEWLARALPDEPAEALEELLALSGGSPLTAQRLHGQGVREQRAQVVEGVKKLLKQQIAASPLAESWNSVPLPLLFDWFCDWTLGILRYQLTHDEEGLGLADMRKVIQYLGDKSGQAKVLAMQDWLLQQRQKVLNKANLNRVLLLEALLVQWASLPGPG
What is the function of this protein?
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.  This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity).
What are the official names of this protein?
DNA polymerase III subunit delta'.
Protein: SYK_MOUSE
Sequence: MATLQESEVKVDGEQKLSKNELKRRLKAEKKLAEKEAKQKELSEKQLNQTASAPNHTADNGVGAEEETLDPNQYYKIRSQAVQQLKVTGEDPYPHKFHVDISLTQFIQEYSHLQPGDHLTDVTLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFVHINNKLRRGDIIGVEGNPGKTKKGELSIIPQEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNDFVRQKFIVRSKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEFYMAYADYHDLMEITEKMLSGMVKSITGSYKITYHPDGPEGQAYEVDFTPPFRRISMVEELEKALGVKLPETSLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEFLEVTCISPTFICDHPQIMSPLAKWHRSKEGLTERFELFVMKKEICNAYTELNDPVRQRQLFEEQAKAKAAGDDEAMFIDENFCTALEYGLPPTAGWGMGIDRLTMFLTDSNNIKEVLLFPAMKPEDKKETAATTETPESTEASPSV
What is the function of this protein?
Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA.  When secreted, acts as a signaling molecule that induces immune response through the activation of monocyte/macrophages.  Catalyzes the synthesis of the signaling molecule diadenosine tetraphosphate (Ap4A), and thereby mediates disruption of the complex between HINT1 and MITF and the concomitant activation of MITF transcriptional activity.
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein. Secreted. Note=Secretion is induced by TNF-alpha. Cytosolic in quiescent mast cells. Translocates into the nucleus in response to mast cell activation by immunoglobulin E.
Protein: SC22B_PONAB
Sequence: MVLLTMIARVADGLPLAASMQEDEQSGRDLQQYQSQAKQLFRKLNEQSPTRCTLEAGAMTFHYIIEQGVCYLVLCEAAFPKKLAFAYLEDLHSEFDEQHGKKVPTVSRPYSFIEFDTFIQKTKKLYIDSRARRNLGSINTELQDVQRIMVANIEEVLQRGEALSALDSKANNLSSLSKKYRQDAKYLNMRSTYAKLAAVAVFFIMLIVYVRFWWL
What is the function of this protein?
SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
What are the official names of this protein?
Vesicle-trafficking protein SEC22b, SEC22 vesicle-trafficking protein homolog B, SEC22 vesicle-trafficking protein-like 1.
What is the protein family that this protein belongs to?
Belongs to the synaptobrevin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane. Golgi apparatus, cis-Golgi network membrane. Golgi apparatus, trans-Golgi network membrane. Melanosome. Note=Concentrated most in the intermediate compartment/cis-Golgi network and the cis-Golgi cisternae 1 and 2. Greatly reduced in concentration at the trans end of the Golgi apparatus.
Protein: KDPC_GEOUR
Sequence: MKEIKPAILFFIVFTILCGGVYPAVVTSIAHAVFPKQAKGSFITDKSGREIGSALIGQPFSDARYFWPRPSATTDFGYNPMTSGGSNSGPTNPDFLKTVGDRVKSLHDTGITGNIPADLVEASASGLDPHITPEAAKVQVPRVAKARGMTMEELKKLVDARTEDRQLGFLGEQRVNVLELNLELDKLSR
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RRF_BIFA0
Sequence: MANVVDQSKEQMKKSVESTKENFAGIRTGRANPALLNGIVVEYYGAPTPLKHVATIGVPEPRTLSVTPFDPSQANAVEKALRDSDLGASPRRNGSAILLTMPELTEDRRKEYVKLAKSKAEDGKVAVRNIRRKSKEAIDKAVKDGEMGEDEGDRLLKELDKVTKATTDELDALLEAKQKEIMEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHEA_MYCSS
Sequence: MPRIAYLGPQGTFTESALLQMISGAMVPGGDADDTAVTPVPTDSTPAGLEAVRSGAADYACVPIENSIEGSVLPTLDSLAVGAPLQIFAELTLAVSFSIVVRPDHDGDVGTVAAFPVAAAQVRRWLAEHLPAAQLVPAHSNAAAAADVAGGRADAGISTALAAERYGLRSLAAGVVDEPNARTRFVLVGRPAPPPARTGADRTSVALRLPNTPGALVAAMTELSIRDIDLTRIESRPTRTELGTYVFFLDCVGHLEDDAVAEALKALHRRCEDVRYLGSWPTGTAAGAPPPSSDEATRWLTRLREGLPTPPEGGR
What are the official names of this protein?
Prephenate dehydratase, PDT.
Protein: RS20_FLAPJ
Sequence: MANHKSALKRIRSNEKKRVLNRYQHKTTRNAIKALRIATDKTEATAKLSNVISMIDKLAKKNIIHDNKASNLKSKLTRFVSSL
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: MURB_BRUMB
Sequence: MMESGEALLKKLDGRLSGLRGRLTPDTGMDKITWFRAGGPAQVLFQPSDEEDLSAFLKAVPEEIPLLVVGIGSNLLVRDGGVPGFVVRLSAKGFGEVEQVCDTQLRAGAAAPDKRVAAAALEAGLAGFHFYHGIPGGIGGALRMNAGANGVETRERVVEVRALDRKGEVHVLSNADMGYAYRHSSASPDLIFTSVLFEGVPGERDDIRRAMDEVQHHRETVQPVREKTGGSTFKNPEGTSAWKEIDKAGCRGLRVGGAQMSEMHCNFMINTGNATGHDLETLGETVRARVFENSGIRLHWEIKRLGLFREGEQIEEFLGKIV
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ABPB_ECOLI
Sequence: MTEIYEQAKHSLQGEDFSSFNYLFAVNKLLSNPVSYDLGRDLIVRALDSRERFSEHTTILKNMVRKSGLFPYLKKEFTSLTPDDLRVLELYRTPFSDGYVFHSMQFHIFDLLKSGQNVVLSAPTSMGKSAIVDSLLGMGTLKRLVLVVPTVALADETRRRLQERFGDRYQIIHHSSQVCHSDQAVYVLTQERVNERDDIVDIDLFVIDEFYKLAFRQLKSGDIDHQDERVIELNIALSKLLKVSRQFYLTGPFVNSIRGLEKLGYPHTFVSTDFNTVALDVKTFGIKANDDKAKLKALGEIAHACVDATIIYCKSPTVAGLVARELIRLGHGTPTENPHVDWVSEEFDADWDYTVALRNGIGLHFGALPRALQQYTADQFNAGKLRFLLCTSTIIEGVNTIAKNVVIYDNRDGTRSIDKFTHGNIKGRAGRMGVHFVGKIFCLEEIPEDNLNQEVDIPLGIQGIDTPINLLASVQPDHLSEFSQDRFDEVFINDRVSIDLVKKHSYFRVEQFEMLQSMFEMMDDNEFSSLVFHWTPATNFLKTFAKIIARLVPHTFSRNGVPVKPTDVMIAKLAGYLSAESYSEYLKNQIDYARQWISEGEKRTLSIALNNDLKLITNTFGYTLPKVLSLMEDVVKHHAVKRGIRSKVDYTHVKLAFESFHLPPGVNALEEIGIPIQTLHRLVDLLEFSDEADVDELSQYLRDTQDIWSRSIGYVDQMFIRRALGIRRH
What is the function of this protein?
Deletion or mutations in this gene were selected in directed evolution experiments for resistance to intense ionizing radiation (3000 Gy).
What are the official names of this protein?
Anti-bacteriophage protein B, Probable helicase AbpB.
What is the protein family that this protein belongs to?
Belongs to the helicase family.
Protein: Y453_METJA
Sequence: MGCIDKLNYEILYKGGFKECAEYIRKNFKNIKEMEAGYEIFEGIFLIGIPPIPVAYEDNYVIFPYTKPCYGTFVLKINLDEINKDKKEEKKEKDKGKKGLLSRLKFW
What are the official names of this protein?
Uncharacterized protein MJ0453.
Protein: ACCD_POPAL
Sequence: MKKCWFHSMLSNVELEYRCRLSKSMDNLGPLENTSVSEDPILNDTEKNTYNWSHSDSSNVDHLVGVRDIRNLNVDDTFLVLGRDNKKDGYSIYFDIENQVFGIDNNHSFLSELEKEFSSYWNSSYLNKGSRSDDSHYDYSMYDNKYSWNNYINSCIDSYLRSQIGIASSILSGSENCSESYISTYILGESRNSSETGNSRLRTSTNGSDFALKENSNDLGVTQKYKHLWVQCEICYGLNYKKFFKSKMNICEQCGYHLKMSSSDRIELSIDPGTWDPMDEEMFSLDPIDFHSEEEPYKDRIDSYQKKTGLTEAIQTGIGQLNGIPVAIGVMDFQFMGGSMGSVVGEKITRLIEYATNQFLPLILVCASGGARMQEGSLSLMQMAKISSALYDYQSNKKLVYVSILTSPTTGGVTASFGMLGDIIIAEPNAYIAFAGKRVIEQTLNKTVPEGSQAAEFLFHKGLFDPIVPRNLLKGVLSELFQLHAFFPLNHNLSRTLT
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: HIS7_BACAA
Sequence: MRESSQIRETTETKIKLSLQLDEGKNVSVQTGVGFFDHMLTLFARHGRFGLQVEAEGDVFVDAHHTVEDVGIVLGNCLKEALQNKEGINRYGSAYVPMDESLGFVAIDISGRSYIVFQGELTNPKLGDFDTELTEEFFRAVAHAANITLHARILYGSNTHHKIEALFKAFGRALREAVERNAHITGVNSTKGML
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_STRZT
Sequence: MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGGVVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKTFAWAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETRDDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSAFINLYHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANKGLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDTME
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_STAA1
Sequence: MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQKTVKKVDEAYNFLKQVSEDGGQVLFVGTKKQAQESVKSEAERAGQFYINQRWLGGLLTNYKTISKRIKRISEIEKMEEDGLFEVLPKKEVVELKKEYDRLIKFLGGIRDMKSMPQALFVVDPRKERNAIAEARKLNIPIVGIVDTNCDPDEIDYVIPANDDAIRAVKLLTAKMADAILEGQQGVSNEEVAAEQNIDLDEKEKSEETEATEE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: CUTC_YERP3
Sequence: MTKLEVCCYSVDCAQIAEKAGADRVELCCGQSEGGLTPSVGALIQARETVTIPVHPIVRPRGGDFCYSSNDFTIMKNDIARIRDLGFAGVVVGVLDTDGHIDMPRMREIMSVSGSLAVTFHRAFDMCQNPMIALKQLAELNVARILTSGQQQNAELGLALLKDLVAATKDQGPIIMAGAGVRLTNMQKFIDAGIRELHSSAGRTVPSTMRYRKAGVTMCADSDVDEFSHYCVDGEVVEAMKSLLVMGSPLAKHT
What are the official names of this protein?
PF03932 family protein CutC.
What is the protein family that this protein belongs to?
Belongs to the CutC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIS1_CAEEL
Sequence: MSLSERQKEEINRAIAEYMQNNGYSESFSVFLKESSLSENDIKPLGGILEKKWTTVLRLQRKVNDLESKLQESQREINHGAPTRDKRQAADWIPRPPETQKLTGHRLPITRVIFHPLWTIMASCSEDATIKVWDYETGQLERTLKGHTDAVNDIAIDAAGKQLVSCSSDLSIKLWDFGQTYDCLKSLKGHEHTVSSVTFLPTGDFVLSASRDHTIKQWDISTGYCVYTFRGHNDWVRMIRISNDGTLFASASLDQTVTVWSFATKSAKLVLRDHEHAVECVEWAPDTAYTNVTGQQPEGNSTHILFSGSRDRSIKAWNINTGDVLFTLLAHENWVRGLAFHPKGKYLISVADDKTLRVWELSAQRCMKAIEAHEHFVSTVAFHQTSPFVITGSVDMSCKVWECR
What is the function of this protein?
Positively regulates the activity of the minus-end directed microtubule motor protein dynein.  May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end.  Required for several dynein- and microtubule-dependent processes such as nuclear migration during cell division (PubMed:11685578, PubMed:15331665).  Part of a complex with nud-2, which is recruited to the nuclear envelope by unc-83, where, in turn, it recruits dynein to the nuclear surface and regulates nuclear migration in hypodermal precursor cells (PubMed:20005871).  Plays a role in GABAergic synaptic vesicle localization in the ventral nerve cord (PubMed:16996038).  Required for neuronal cell differentiation (PubMed:15254012).
What are the official names of this protein?
Lissencephaly-1 homolog, Pronuclear migration abnormal protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LIS1/nudF family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore. Nucleus envelope. Note=Localizes to the plus end of microtubules (By similarity). Concentrates in the vicinity of microtubule asters, kinetochores, the cell cortex and the perinuclear region (PubMed:15331665). Probably recruited to the nuclear envelope by unc-83 (PubMed:20005871).
Protein: GOLP3_RAT
Sequence: MTSLTQRSSGLVQRRTEASRNAADKERAAGGGGGNGEDEAQSRRDEQDDDDKGDSKETRLTLMEEVLLLGLKDREGYTSFWNDCISSGLRGCMLIELALRGRLQLEACGMRRKSLLTRKVICKSDAPTGDVLLDEALKHVKETQPPETVQNWIELLSGETWNPLKLHYQLRNVRERLAKNLVEKGVLTTEKQNFLLFDMTTHPLTNNNIKQRLIKKVQEAVLDKWVNDPHRMDKRLLALIYLAHASDVLENAFAPLLDEQYDLATKRVRQLLDLDPEVECLKANTNEVLWAVVAAFTK
What is the function of this protein?
Phosphatidylinositol-4-phosphate-binding protein that links Golgi membranes to the cytoskeleton and may participate in the tensile force required for vesicle budding from the Golgi.  Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus.  May also bind to the coatomer to regulate Golgi membrane trafficking.  May play a role in anterograde transport from the Golgi to the plasma membrane and regulate secretion.  Has also been involved in the control of the localization of Golgi enzymes through interaction with their cytoplasmic part.  May play an indirect role in cell migration.  Has also been involved in the modulation of mTOR signaling.  May also be involved in the regulation of mitochondrial lipids biosynthesis.
What are the official names of this protein?
Golgi phosphoprotein 3, Coat protein GPP34, Trans-Golgi protein GMx33.
What is the protein family that this protein belongs to?
Belongs to the GOLPH3/VPS74 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein; Cytoplasmic side. Mitochondrion intermembrane space. Cell membrane. Endosome. Note=Phosphatidylinositol 4-phosphate-binding and oligomerization participate in the recruitment onto Golgi membranes.
Protein: GRPE_BURM1
Sequence: MENTQENPASQSAEENGSETQAAQDAAPAAEAADAALAEAQAKVAELQESYLRAKAETENVRRRAQEDVAKAHKFAIESFAEHLLPVLDSLEAAVGDTSGDIAKVREGVELTLRQLTSALEKGRVVAINPVGEKFDPHRHQAISMVPADQEPNTVVTVLQKGYTIADRVLRPALVTVAQPK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YGJV_ECOLI
Sequence: MTAYWLAQGVGVIAFLIGITTFFNRDERRFKKQLSVYSAVIGVHFFLLGTYPAGASAILNAIRTLITLRTRSLWVMAIFIVLTGGIGLAKFHHPVELLPVIGTIVSTWALFCCKGLTMRCVMWFSTCCWVIHNFWAGSIGGTMIEGSFLLMNGLNIIRFWRMQKRGIDPFKVEKTPSAVDERG
What are the official names of this protein?
Inner membrane protein YgjV.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MATK_LUPAG
Sequence: MEEYQVYLELDISRQQHLLYPLIFREYIYGLVYGHDFNGSIFLENLDYDNKSSLLIVKRLITRMDQQNHLIISANDSKKNQFLSYNKNLYSQIISEGFAIVVEIPLSLQLNSSSEESKIIKYYKNLRSIHSIFPFFEDKLTYLNYVSDARIPYPIHLXXXXXXXXXXXXXXPLFHLLRLFFYEYCNWNNLITPKKSISTFSKSNLRVFLFLYNFYVCQYESIFLFLRNKSSHLRLTSFIVLFERIYFYGKIEHFLEVFAKDFSSTFFKELFIHYVRYQEKYILASKNASLLMNKWKNYLIRLWQYHFDVWSQPRTIQINQFSEGSFRLLGYFSNVRLNRSAVRSQMLENSFLIEIVMKKLETIVPIIPLIRSLAKAKFCNVLGHPISKPVWADSSDFYIIDRFLQICRNLSHYYNGSSKKKSLYRVKYILRLSCIKTLARKHKSTVRAFLKRLGSEKLLEEFFTEEEEILSLVFQRVSSTLQGLYRGRVWYLDIIFSNDLVNHE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RPOZ_DICNV
Sequence: MARVTVEDCLIHENSRFRLVLAASKRARQLTLGHQPLVAPENDKPTVLALREIEEGKVTVQGLLDGQDVSEHLARQA
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: IF2G_PIG
Sequence: AGTEAGVTLGQPSLXEQDSXXL
What is the function of this protein?
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.  This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex.  Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex.  In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
What are the official names of this protein?
Eukaryotic translation initiation factor 2 subunit 3, Eukaryotic translation initiation factor 2 subunit gamma, eIF-2-gamma.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding elongation factor family. EIF2G subfamily.
Protein: LSPA_COXBN
Sequence: MVTKKSKKAWPWLWLSVLVILLDQLSKYLANHFLSLGHPVKILPFLNFTLNYNTGAAFSFLGTENGWQIIFFAAISFVVSIFLILWLSRTSRSEIMMSLGLSLIIGGALGNFIDRLRWSYVTDFIDFHIKDWHFATFNVADSAICVGVFLLIVYMLLTPSSKP
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RIMP_LIMF3
Sequence: MSNKTVVETVTALVEPILAEHNFELYEVEFVQEAKSWYLRVYIDKEGGITLEDCALVSDQLSEQLDSADPDPIPQAYFLEVSSPGAERPLKKEVDYQRALDQYVNVSLYQQIDGHKVFEGYLRQLSPDELTIEYMDKTRQKQVVIPRDKVAKARLAIKF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDGD_ACIET
Sequence: MTPQDLKNVMSSGLLSFPITDFHDNGDFNAKGYAERLEWLAPFGASALFAAGGTGEYFSLTASEYPQIIQTAVNTCRGKVPIIAGAGGPTRFAIECAQAAEKAGAHGILLMPHYMTEASQEGLAAHVEAVCKSVNFGVIIYNRGITRYTPETVARLCERNPNLVGFKDGVGDIEGMASMFLAMGDRLAYLGGLPTAEVYAAAYKALGTPVYSSAVFNFIPKTAMRFYEAVKNDDQATQHQLLKDFFMPYLKIRNRSAGYAVSIIKAGAKIVGHPAGPVRAPLADLQAEEIEMLAELIRKVEPV
What are the official names of this protein?
Probable 5-dehydro-4-deoxyglucarate dehydratase, 5-keto-4-deoxy-glucarate dehydratase, KDGDH.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
Protein: RBM48_DANRE
Sequence: MDGSVASSSVWDTQKVYKHHEQQNVAQTRPKYREGRRLKAVKVYTINLESRYLLVQGVPAIGVMAELVQLFALYGVIEEYRPLDEYPAEQFTEVYLIQFQKLTSARAAKRHTDEKSFFGGQLHVCYAPEYETVEETKQKLQDRRRYVNWASQNAAKLHSQQAEVNTESSSSTDTRTAEAPIMQKNPEEARRENVNSDYMGFPLLPLPPTADISYRLQNHFTQPSQLQWTKETTEDKMGSLHNFIPPVQKTSTQSESSSSSGVKEGDLRQKQKISTPSIRFMPRTTHLESRKRKLDEQTFFLKEADKTGVLIGPKLPELPKLDMEDSSLNVTANLIRNTMTKAASVPEAKPVQAKHTTPKPRRRI
What is the function of this protein?
As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs.
What are the official names of this protein?
RNA-binding protein 48.
What is the protein family that this protein belongs to?
Belongs to the RBM48 family.
Protein: KTU_MOUSE
Sequence: MAKAAASSALEDLDLSREEVQRFTSAFQDPEFRRMFSEYAAEITDPENRRRYEEEITALERERGVDVRFVHPEPGHVLRTSLDGEHRCYVNVCSNSLVGVPSSRPGPGRGGTAAGSHWSLPYSLAPGRQYAGRNGARYTVYDVVFHPEALALARSHERFREMLDATALEAVEQQFGVRLDRRNAKTLKIKYKGMPEAAVLRTPLPGGVPAQPEGEPPGLFPDPPYPYRYPAAAAANTARSPASPAPEAVQRPEPTEPRCSVVQRHHVDLQDYRCSRDAAPSTVPHELVVTIELPLLRSVERAELEVKGKLLCLDSRNPDYRLRLSLPYPVDDGRGKAQYNKARRQLVVTLPVALADARQEPPAATPEEPAEETGTDDVARTSAGDFAAAREESADGTGADHGEKSGVGAPDPGAAHAEGELVPEPEQDFGGDSVAPLDLGKGTSPGDRSLPYSAFPGGDTESLCGDPGVQTNEEQERTRHDTAGSAMGDPGTESIAPVCPPLQCNQDEDSLTLLIQVPGILPQTLHGHLSPVGYELCFSTQDSGYSCTLQFAPENKLSTREPETSVSLNNAVIVLAKSPESHGLWREWYCGLNKESLEERLFINEENVNGFLEEVLCSPLKQARSLAPPLIEVLQATDEQVQIHAELQECSDPAGLQGKGKGVREGCPLSEAEAADQSATSPAASDSAAAVEALKINTHGSAVDLQHGCPEVPHVLSGKPLQPEAKMDPEFIRESSTTYSTEEKENIREPVISKGEKINGDHPSSLLNKTVVQNIPDFDTIKETNMQDGSVQIIRDHTTHCAFSFQNPLLYDLD
What is the function of this protein?
Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella.  Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment.
What are the official names of this protein?
Protein kintoun, Dynein assembly factor 2, axonemal.
What is the protein family that this protein belongs to?
Belongs to the PIH1 family. Kintoun subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Dynein axonemal particle. Note=Localizes in the apical cytoplasm around the gamma-tubulin-positive pericentriolar region, not in the cilia.