PharMolix/UniProtQA huggingface dataset:
Protein: RAB4B_DANRE
Sequence: MSETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARTLASPNIVIILCGNKKDLDADREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARSIPNKIESGELDPERMGSGIQYGDASLRQIRQPRGSAAQTKQQCNC
What is the function of this protein?
Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state (By similarity).  Protein transport.  Probably involved in vesicular traffic (By similarity).
What are the official names of this protein?
Ras-related protein Rab-4B.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: AAXA_CHLTB
Sequence: MSFRSVLLTALLSLSFTTTMQAAHHHYHRYTDKLHRQNHKKDLISPKPTEQEACNTPSLSKELIPLSEQRGLLSPIYDFISERLCLHGVSVRNLKQALKNSAGTQIALDWSILPQWFNPRVSHAPKLSIRDFGYSAHQTVTEATPPCWQNCFNPSAAVTIYDSSYGKGVFQISYTLVHYWRENAATAGDAMMLAGSINDYPSRQNIFSQFTFSQNFPNERVSLTIGQYSLYAIDGTLYNNDQQLGFISYALSQNPTATYSSGSLGAYLQVAPTASTSLQIGFQDAYNISGSSIKWSNLTKNRYNFHGFASWAPRCCLGSGQYSVLLYVTRQVPEQMEQTMGWSVNASQYISSKLYVFGRYSGVTGHVFPINRTYSCGMVSANLFNRNPQDLFGIACAFNNVHLSASPNAKRKYETVIEGFATIGCGPYLSFAPDFQLYLYPALRPNKQSARVYSVRANLAI
What is the function of this protein?
Facilitates L-arginine uptake, as part of the AaxABC system.  The arginine uptake by the bacterium in the macrophage may be a virulence factor against the host innate immune response (By similarity).
What are the official names of this protein?
Porin AaxA, Outer membrane protein AaxA.
What is the protein family that this protein belongs to?
Belongs to the OprB family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: REXA_LAMBD
Sequence: MKNGFYATYRSKNKGKDKRSINLSVFLNSLLADNHHLQVGSNYLYIHKIDGKTFLFTKTNDKSLVQKINRSKASVEDIKNSLADDESLGFPSFLFVEGDTIGFARTVFGPTTSDLTDFLIGKGMSLSSGERVQIEPLMRGTTKDDVMHMHFIGRTTVKVEAKLPVFGDILKVLGATDIEGELFDSLDIVIKPKFKRDIKKVAKDIIFNPSPQFSDISLRAKDEAGDILTEHYLSEKGHLSAPLNKVTNAEIAEEMAYCYARMKSDILECFKRQVGKVKD
What is the function of this protein?
May confer an overall protective ability to the host cell by triggering a growth arrest and avoiding lethal host gene expression.  Additionally, may confer symbiotic protection to the lysogenic host against secondary infection.
What are the official names of this protein?
Protein rexA.
Protein: SRP68_YEAST
Sequence: MVAYSPIIATYGNRAEQFLETDSDFAKYHAKLNKKLQHLRSRCHLVTKDTKKYSSKNKYGEINSEDYDNKTKLIGVLILLHAERDLALAETLKLRARQRGKLKKSEEKVLSTRLKKACKTADKLVNVTQNEQQWITRAQYLAFAKLVHSEYLINGKRFKRKDNAKISNNLALVFAALEHLKNLSLLAEEVVDNIVNKYQYSLKQYAGNLITTPEINNFIVERVQSDENKDDELVKLLLDNGFNMKKITTSTEDQKVTTNINWRSFNAKIIDAEVAQFLEQGLSIHPTQITQYTQRLSKLEKALDRHEFFIANHDDQDDIDEMVENSSENNQIILAYIKYNILLTSISRERDLFTHLWNQWLKLNTSLPSKLTKYKEMERIVKNLTKYLSDIMELPGVYSDDELLSQLDLCKLYFQLFLNTGCLSVLYQSKGRYMEALALYVDAYRRLENKLSEIESLDEILLPANLLSLNSVRSLQKRIENGGNSVITLAEYEKRNHGGSLGKYDLTVIEKLDSKKILPTDIQLKNLFPLKPKMLPIPSKPTLFDLAFNYITYDKQEPSASQVKDSVTETESISQTPISNEQTEGEPKKKRGFLGLFGR
What is the function of this protein?
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (PubMed:7925282).  The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER (By similarity).  The SRP complex targets the ribosome-nascent chain complex to the SRP receptor (SR), which is anchored in the ER, where SR compaction and GTPase rearrangement drive cotranslational protein translocation into the ER (By similarity).  Binds the signal recognition particle RNA (7SL RNA), SRP72 binds to this complex subsequently (By similarity).  The SRP complex possibly participates in the elongation arrest function (PubMed:7925282).
What are the official names of this protein?
Signal recognition particle subunit SRP68, Signal recognition particle 68 kDa protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SRP68 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus.
Protein: IASPP_HUMAN
Sequence: MDSEAFQSARDFLDMNFQSLAMKHMDLKQMELDTAAAKVDELTKQLESLWSDSPAPPGPQAGPPSRPPRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPYSPLSPKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQQGPPTPFDFLGRAGSPRGSPLAEGPQAFFPERGPSPRPPATAYDAPASAFGSSLLGSGGSAFAPPLRAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFARPASPSLQLLPWRESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGSAGPSGTLPRSWQPVSRIPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSPITEGSEARAGPPAPAPPAPIPPPAPSQSSPPEQPQSMEMRSVLRKAGSPRKARRARLNPLVLLLDAALTGELEVVQQAVKEMNDPSQPNEEGITALHNAICGANYSIVDFLITAGANVNSPDSHGWTPLHCAASCNDTVICMALVQHGAAIFATTLSDGATAFEKCDPYREGYADCATYLADVEQSMGLMNSGAVYALWDYSAEFGDELSFREGESVTVLRRDGPEETDWWWAALHGQEGYVPRNYFGLFPRVKPQRSKV
What is the function of this protein?
Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins.  Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1.  Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis (PubMed:12524540).
What are the official names of this protein?
RelA-associated inhibitor, Inhibitor of ASPP protein, Protein iASPP, NFkB-interacting protein 1, PPP1R13B-like protein.
What is the protein family that this protein belongs to?
Belongs to the iASPP family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic but also nuclear.
Protein: SURE_METCA
Sequence: MHILLSNDDGYAAPGLRALAAALSPLAKITVVAPERNRSGASNSLTLERPLRATRAENGFIRVDGTPTDCVHLAITGLLDSEPDMVFAGINHGANLGDDVIYSGTVAAATEGRFLGLPAVAISLAAHNPEHFETAAQVAIELLERIRENPLPADTILNVNVPDIPPDELRGYRATRLGARHKAEAVVRTRDPRGREIFWVGCAGPEADAGPGTDFHAIRQNCVSVTPLQIDLTRYERLDQLGAWLPGRVTA
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX1_PECMA
Sequence: MVRWSRWFMANSHKDVGTMYLMLGMWSGFGGLNLSWMMRLELSRPGMWLPSSEVYNGIVTLHAIMMIFSFVMPVLIGGFGNWLLPMMLGSIDMSFPRLNTFSFWVLPPALYLVIVSCFIDYGSGTGWTMYPVPLSSTPYSGGISTDLMILGLHLAGISSSAESINYLVTFLNVRSKSFKAEFSPLFVWALAVTSFLLLVSLPVLAGGLTMLIMDRDFNCSFFDPSGGGDPVLFQHLFWFFGHPEVYVLILPGFGLVSHVLVFYTKKLRVFGSVAMMYAMISIGVLGFIVWGHHMYTVGLDVDTRFYFTAVTMLIAVPTGVKVFSWIATIYGSYLSFEAPTLWVLGFIMKFTMGGITGVILSNACLDVALHDTYYVVAHFHYVLSMGAVFTIFAGYIHYFPFFTSKLFSPVLARGHFFLTFVGVNLTFFPQHFLGLGGMPRRIPDYPIFYYYWNQWSTIGCAMVMVSVSLFIHMQWEA
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ERPA_HYDCU
Sequence: MSEMPTPVNFTEAAASKVSGLIQDEGNPELKLRVYITGGGCSGFQYGFTFDESQAEDDTVVEKDGVKLMIDPMSFQYLMGAKIDYLEDLQGARFVIENPNASTTCGCGSSFGV
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: HGD_CAEEL
Sequence: MSEFDELKYLTGFGNEHATSDPRVPDALPVGQNSPQKCSHGLYAEQLSGTAFTAPRSQNQRSWLYRIRPSVIHRPFEAMKENDQHWTNNFSSIPPNPNQYRWNPFPLPTKEGVTFVDNLYTVCGGGDVISRTGLAIHQFSCNASMEHTAMYNSDGDFLIVPQQGALEITTEFGRLLVNPQEIAVIPQGIRFSVAVRGPSRGYILEVYGTHFQLPDLGPIGANGLANPRDFEAPVAWFEDLDVEFTIINKYQGSWFQAKQGHSPFDVVGWHGNYVPYKYDLKKFMVINTVSFDHCDPSIFTVLTAPSVKHGTAIADFVIFPPRWGCADNTFRPPYYHRNCMSEYMGLITGCYEAKEGGFKPGGGSLHSMMTPHGPDFNCFEMASNADLKPQRVAEGTMSFMFESSLNMAITNWAVYQNVDKDYYKDWQPLKKHFTMPK
What is the function of this protein?
Plays a role in the tyrosine degradation pathway.
What are the official names of this protein?
Homogentisate 1,2-dioxygenase, Homogentisate oxygenase, Homogentisic acid oxidase, Homogentisicase.
What is the protein family that this protein belongs to?
Belongs to the homogentisate dioxygenase family.
Protein: RL331_LISMO
Sequence: MRVNITLECTECGDRNYITTKNKRENPERIELKKYCPRLRRVTLHRETK
What are the official names of this protein?
50S ribosomal protein L33 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: Y848_STRR6
Sequence: MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEVSRFLEEHASFSFNLGDFDSIWQEYLEH
What are the official names of this protein?
UPF0346 protein spr0848.
What is the protein family that this protein belongs to?
Belongs to the UPF0346 family.
Protein: KSL11_ORYSI
Sequence: MMLLSSSYSGGQFPGVSPLGTRPKRSTTVVPLPVVTRATAGGVRNNLEVVGNAGTLQGMDIDELRVIVRKQLQGVELSPSSYDTAWVAMVPVQGSPQSPCFPQCVEWILQNQQEDGSWGHSAGPSGEVNKDILLSTLACVLALNTWNVGQDHIRRGLSFIGRNFSVAIDGQCAAPVGFNITFSGMLHLAIGMGLKFPVMETDIDSIFRLREVEFERDAGGTASARKAFMAYVSEGLGREQDWDHVMAYQRKNGSLFNSPSTTAASAIHSCNDRALDYLVSLTSKLGGPVPAIHPDKVYSQLCMVDTLEKMGISSDFACDIRDILDMTYSCWMQDEEEIMLDMATCAKAFRLLRMHGYDVSSEGMARFAERSSFDDSIHAYLNDTKPLLELYKSSQLHFLEEDLILENISSWSAKLLKQQLSSNKIMKSLMPEVEYALKYPLYSTVDALEHRGNIERFNVNGFQRPKSGYCGSGADKEILALAVDKFHYNQSVYQQELRYLESWVAEFGLDELKFARVIPLQSLLSALVPLFPAELSDARIAFSQNCMLTTMVDDFFDGGGSMEEMVNFVALIDEWDNHGEIGFCSNNVEIMFNAIYNTTKRNCAKAALVQNRCVMDHIAKQWQVMVRAMKTEAEWAASRHIPATMEEYMSVGEPSFALGPIVPLSAYLLGEELPEEAVRSPEYGQLLRHASAVGRLLNDVMTYEKEVLTWTPNSVLLQALAAARGGGESPTPPSPACAEAARGEVRRAIQASWRDLHRLVFRDDDGSSIVPRACRELFWGTAKVANVFYQEVDGYTPKAMRGMANAVILDPLHLQQ
What is the function of this protein?
Catalyzes the conversion of syn-copalyl diphosphate to stemodene.
What are the official names of this protein?
Stemod-13(17)-ene synthase, Ent-kaurene synthase-like 11, OsKSL11, Stemodene synthase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: YMFQ_ECOLI
Sequence: MDVTNDDYIRLLSALLPPGPVWSASDPAIAGAAPSLTRVHQRADALMRELDPRTTTELINRWERLCGLPDECIPAGTQTLRQRQQRLDAKVNLAGGINEDFYLAQLAALGRPDATITRYDKSTFTCSSACTDAVNAPEWRYYWQVNMPATTNSTWMTCGDPCDSALRIWGDTVVECVLNKLCPSHTYVIFKYPE
What are the official names of this protein?
Uncharacterized protein YmfQ, Uncharacterized protein YmfQ in lambdoid prophage e14 region.
What is the protein family that this protein belongs to?
To phage Mu protein gp48 and H.influenzae HI_1521.
Protein: SYGB_STRA1
Sequence: MTKDLLLELGLEELPAYVVTPSEKQLGQKMVKFLEDHRLSFETVQTFSTPRRLAVRVKGLADQQTDLTEDFKGPSKKIALDAEGNFSKAAQGFVRGKGLSVDDIEFREVKGEEYVYVTKHETGKSAIDVLASVTEVLTELTFPVNMHWANNSFEYIRPVHTLVVLLDDQALELDFLDIHSGRISRGHRFLGSDTEISSASSYEDDLRQQFVIADAKERQQMIVNQIHAIEEKKNISVEIDEDLLNEVLNLVEYPTAFLGSFDEKYLDVPEEVLVTSMKNHQRYFVVRDRDGKLLPNFISVRNGNAEHIENVIKGNEKVLVARLEDGEFFWQEDQKLNIADLVEKLKQVTFHEKIGSLYEHMDRVKVISQYLAEKADLSDEEKLAVLRAASIYKFDLLTGMVDEFDELQGIMGEKYALLAGEQPAVAAAIREHYMPTSADGELPETRVGAILALADKFDTLLSFFSVGLIPSGSNDPYALRRATQGIVRILEAFGWDIPLDELVTNLYGLSFASLDYANQKEVMAFISARIEKMIGSKVPKDIREAVLESDTYIVSLILEASQALVQKSKDAQYKVSVESLSRAFNLAEKVTHSVLVDSSLFENNQEKALYQAILSLELTEDMHDNLDKLFALSPIINDFFDNTMVMTDDEKMKQNRLALLNSLVAKARTVAAFNLLNTK
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CATL1_CANLF
Sequence: MNPSLFLTALCLGIASAAPKFDQSLNAQWYQWKATHRRLYGMNEEGWRRAVWEKNMKMIELHNREYSQGKHGFTMAMNAFGDMTNEEFRQVMNGFQNQKHKKGKMFQEPLFAEIPKSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRAQGNEGCNGGLMDNAFRYVKDNGGLDSEESYPYLGRDTETCNYKPECSAANDTGFVDLPQREKALMKAVATLGPISVAIDAGHQSFQFYKSGIYFDPDCSSKDLDHGVLVVGYGFEGTDSNNKFWIVKNSWGPEWGWNGYVKMAKDQNNHCGIATAASYPTV
What is the function of this protein?
Thiol protease important for the overall degradation of proteins in lysosomes (By similarity).  Plays a critical for normal cellular functions such as general protein turnover, antigen processing and bone remodeling.  Involved in the solubilization of cross-linked TG/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen (By similarity).  In neuroendocrine chromaffin cells secretory vesicles, catalyzes the prohormone proenkephalin processing to the active enkephalin peptide neurotransmitter (By similarity).  In thymus, regulates CD4(+) T cell positive selection by generating the major histocompatibility complex class II (MHCII) bound peptide ligands presented by cortical thymic epithelial cells.  Also mediates invariant chain processing in cortical thymic epithelial cells.  Major elastin-degrading enzyme at neutral pH.  Accumulates as a mature and active enzyme in the extracellular space of antigen presenting cells (APCs) to regulate degradation of the extracellular matrix in the course of inflammation (By similarity).  Secreted form generates endostatin from COL18A1 (By similarity).  Critical for cardiac morphology and function.  Plays an important role in hair follicle morphogenesis and cycling, as well as epidermal differentiation (By similarity).  Required for maximal stimulation of steroidogenesis by TIMP1 (By similarity).
What are the official names of this protein?
Procathepsin L, Cathepsin L1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Lysosome. Apical cell membrane; Peripheral membrane protein; Extracellular side. Cytoplasmic vesicle, secretory vesicle, chromaffin granule. Secreted, extracellular space. Secreted. Note=Localizes to the apical membrane of thyroid epithelial cells. Released at extracellular space by activated dendritic cells and macrophages.
Protein: ARCA_STRPM
Sequence: MTAQTPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDIPFLEDAQKEHDAFAQALRDEGIEVLYLETLAAESLVTPEIREAFIDEYLSEANIRGRATKKAIRELLMAIEDNQELIEKTMAGVQKSELPEIPASEKGLTDLVESNYPFAIDPMPNLYFTRDPFATIGTGVSLNHMFSETRNRETLYGKYIFTHHPIYGGGKVPMVYDRNETTRIEGGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHLDTVFTMVDYDKFTIHPEIEGDLRVYSVTYDNEELHIVEEKGDLAELLAANLGVEKVDLIRCGGDNLVAAGREQWNDGSNTLTIAPGVVVVYNRNTITNAILESKGLKLIKIHGSELVRGRGGPRCMSMPFEREDI
What are the official names of this protein?
Arginine deiminase, ADI, Arginine dihydrolase, AD.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPSV_CHICK
Sequence: MSSDDDFYLFTNGSVPGPWDGPQYHIAPPWAFYLQTAFMGIVFAVGTPLNAVVLWVTVRYKRLRQPLNYILVNISASGFVSCVLSVFVVFVASARGYFVFGKRVCELEAFVGTHGGLVTGWSLAFLAFERYIVICKPFGNFRFSSRHALLVVVATWLIGVGVGLPPFFGWSRYMPEGLQCSCGPDWYTVGTKYRSEYYTWFLFIFCFIVPLSLIIFSYSQLLSALRAVAAQQQESATTQKAEREVSRMVVVMVGSFCLCYVPYAALAMYMVNNRDHGLDLRLVTIPAFFSKSACVYNPIIYCFMNKQFRACIMETVCGKPLTDDSDASTSAQRTEVSSVSSSQVGPT
What is the function of this protein?
Visual pigments are the light-absorbing molecules that mediate vision.  They consist of an apoprotein, opsin, covalently linked to cis-retinal.
What are the official names of this protein?
Violet-sensitive opsin, Violet cone opsin, Violet cone photoreceptor pigment.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MURD_STAAM
Sequence: MLNYTGLENKNVLVVGLAKSGYEAAKLLSKLGANVTVNDGKDLSQDAHAKDLESMGISVVSGSHPLTLLDNNPIIVKNPGIPYTVSIIDEAVKRGLKILTEVELSYLISEAPIIAVTGTNGKTTVTSLIGDMFKKSRLTGRLSGNIGYVASKVAQEVKPTDYLVTELSSFQLLGIEKYKPHIAIITNIYSAHLDYHENLENYQNAKKQIYKNQTEEDYLICNYHQRQVIESEELKAKTLYFSTQQEVDGIYIKDGFIVYKGVRIINTEDLVLPGEHNLENILAAVLACILAGVPIKAIIDSLTTFSGIEHRLQYVGTNRTNKYYNDSKATNTLATQFALNSFNQPIIWLCGGLDRGNEFDELIPYMENVRAMVVFGQTKAKFAKLGNSQGKSVIEANNVEDAVDKVQDIIEPNDVVLLSPACASWDQYSTFEERGEKFIERFRAHLPSY
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_HALHL
Sequence: MAEERSYFGTDGIRGRVGEAPITPDFVLRLGWAAGRVLAGEGQRKVVIGKDTRLSGYMFESALEAGFAAAGVHSLMLGPMPTPAIAYLTRTLHARAGVVISASHNPHHDNGIKFFGPDGYKLDDATEEAIERLLQDGPPQMVRCEELGRATRINDAVGRYIEFCKGSVQRQIDLRGLRVVVDCAHGATYQAAPAVLAELGADVVVIGNEPDGLNINVDHGSQHPERLCQRVVEASADVGVAFDGDGDRVIMVDRYGRVIDGDGLLYIIATARVARGQVRGAVVGTQMTNLGLEVALQELGLVLERTRVGDRYVLERLLQVGGTLGGESSGHIICLDRTTTGDGLISALQVLEAMVTTGRPLDELVAGMHYYPQRLVNVPVSRGPDVIRLPAVTEAVEEAEHQLGDHGRVLLRPSGTEPLLRVMVEGADEGQVNRLADWLAVTVETAARGAATDPI
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: EIF3M_BOVIN
Sequence: MSVPAFIDISEEDQAAELRAYLKSKGAEISEENSEGGLHVDLAQIIEACDVCLKEDDKDVESVMNSVVSLLLILEPDKQEALIESLCEKLVKFREGERPSLRLQLLSNLFHGMDKNTPVRYTVYCSLIKVAASCGAIQYIPTELDQVRKWISDWNLTTEKKHTLLRLLYEALVDCKKSDAASKVMVELLGSYTEDNASQARVDAHRCIVRALKDPNAFLFDHLLTLKPVKFLEGELIHDLLTIFVSAKLAYVKFYQNNKDFIDSLGLLHEQNMAKMRLLTFMGMAVENKEISFDTMQQELQIGADDVEAFVIDAVRTKMVYCKIDQTQRKVVVSHSTHRTFGKQQWQQLYDTLNAWKQNLNKVKNSLLSLSDT
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis.  The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC).  The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition.  The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit M, eIF3m.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit M family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YHAM_SALTI
Sequence: MFESKINPLWQSFILAVQEEVKPALGCTEPISLALAAAAAAAELDGTVERIDAWVSPNLMKNGMGVTVPGTGMVGLPIAAALGALGGDAKAGLEVLKDASAKAVADAKAMLAAGHVAVMLQEPCNDILFSRAKVYSGDSWACVTIVGDHTNIVRIETDKGVVFTQADNAQEEEKTSPLGVLSHTSLEEILAFVNAVPFDAIRFILDAARLNGALSQEGLRGSWGLHIGSTLAKQCDRGLLAKDLSTAILIRTSAASDARMGGATLPAMSNSGSGNQGITATVPVMVVAEHVGADDECLARALMLSHLSAIYIHHQLPRLSALCAATTAAMGAAAGMAWLIDGRYDTIAMAISSMIGDVSGMICDGASNSCAMKVSTSASAAWKAVLMALDDTAVTGNEGIVAHNVEQSISNLCSLACRSMQQTDKQIIEIMASKAH
What are the official names of this protein?
UPF0597 protein YhaM.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.
Protein: UGTP_BACAH
Sequence: MIKNPKVLILTAHYGNGHVQVAKTLEQTFRQKGIKDVIVCDLFGESHPVITDITKYLYLKSYTIGKELYRLFYYGVEKIYDKKIASWYANFGRKRLKLLLQAEKPDIVINTFPIIAVPELKKQTGISIPVYNVLTDFCVHKIWIHREVDRYFVATDHVKKVMVDIGVPAEQIVETGIPIRSSFELKINPDIIYNKYQLCKNKKILLIVAGAHGVLGSVKELCQSFMSVPDLQVVVVCGKNEALKQDLVGVQETNPDALKVFGYVENIDELFRVTSCMITKPGGITLSEAAALQVPVILYKPVPGQENENAMYFERKGAAVVIRDDSEVFAKTEALLQDDMKLLQMKEAMKSIYRPEPADHIVDTILEENHVEPNHIPIKSPALAQSFT
What is the function of this protein?
Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids.  Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl-sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta-triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol).  Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA).
What are the official names of this protein?
Processive diacylglycerol beta-glucosyltransferase, Beta-diglucosyldiacylglycerol synthase, Beta-DGS, DGlcDAG synthase, Glc2-DAG synthase, Beta-gentiobiosyldiacylglycerol synthase, Beta-monoglucosyldiacylglycerol synthase, Beta-MGS, MGlcDAG synthase, Beta-triglucosyldiacylglycerol synthase, TGlcDAG synthase, Diglucosyl diacylglycerol synthase (1,6-linking), Glucosyl-beta-1,6-glucosyldiacylglycerol synthase, UDP glucosyltransferase, UDP-glucose:1,2-diacylglycerol-3-beta-D-glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. UgtP subfamily.
What are the subcellular locations of this protein?
Cell membrane.
Protein: CL050_BOVIN
Sequence: MEMQQNCSISCFWETQPLGCVKISCIFYHSKPRNINGLFLPPSSNIILQKETQEGIPPPTQSQEPLKPQENISRPIHHPLVLKTNFEEEEEEEGEQNDASSLWTKTPEEIEEKRAIKEMCYKSGEYYRVHTPSDISSSKSIASIVEKEIEKSLESGSELQEGDGLTVPTKFSLFERQGEIKASLDRKPRTDIAAFENGGGDCYVPQRIIFLGVDENEVLTEEKESTISKCSNAKVNDVHPVMKPHFKGVKKRKWIYDEPKNFPEPGMQRVQASNPKNKMSYHRNNKNKNSENASYIHVQRDAVRTVSLNAPPHGRPPHGSYNKADVNKEPKFKLCSDKYMSTSYNGSAWQKRIPFSKTYSKNEKIYTEPRRNGSK
What are the official names of this protein?
Uncharacterized protein C12orf50 homolog.