PharMolix/UniProtQA huggingface dataset:
Protein: TRMB_LIMRJ
Sequence: MRVKHKKWADPLIAAHPELMIDDATQFKGKWQSRFAKEQPLHLEVGMGKGQFIIGMAKDHPEINFIGLEIQRTVAAIALKKALEEDLPNLQLICGDGEDLQEYFEDGEVAKMYLNFSDPWPKKRHAKRRLTYKTFLATYQQILQDQGAIELKTDNMGLFEFSLESMNNYGMIFDGVWLDLHHSEENEHNVETEYEQKFAAKGQPIYKLIANFK
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: CYSH_RHOOB
Sequence: MSVDLSSATEGDLRELAARGAASLEGASARELLQWTEETFGSGASEGTGYRNSFIVASNMQDGVLVHLAAQVHPGVDVLFLDTGYHFAETIGTRDAVEQVYGVNVINARAEASVAEQDAAEGKDLFAREPNRCCALRKVAPLKKTLAGYKAWVTGIRRVEAPTRANAPLISFDDAFGLVKINPIAAWSDEDMQSYIDEHSILVNPLVDEGYPSIGCAPCTSKPAPGSDPRSGRWAGQAKTECGLHAS
What is the function of this protein?
Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
What are the official names of this protein?
Adenosine 5'-phosphosulfate reductase, APS reductase, 5'-adenylylsulfate reductase, Thioredoxin-dependent 5'-adenylylsulfate reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNHF2_STAA3
Sequence: MIQTITHIMIISSLIIFGIALIICLFRLIKGPTTADRVVTFDTTSAVVMSIVGVLSVLMGTVSFLDSIMLIAIISFVSSVSISRFIGGGHVFNGNNKRNL
What are the official names of this protein?
Putative antiporter subunit mnhF2, Mrp complex subunit F2, Putative NADH-ubiquinone oxidoreductase subunit mnhF2.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FADJ_YERP3
Sequence: MGASATNSVTHPAFTLNVRPDNIGIITIDVVGDKVNTLKAEFADQIATILQQAHALPKLQGLVIVSGKPDSFIAGADITMIAACRTAHDARVLAQKGQSILAQIAAFPVPVVAAIHGACLGGGLELALACHSRICSLDDKTVLGLPEVQLGLLPGSGGTQRLPRLVGVSKALDMILTGKQIRPRQALKMGLVDDVVPRDILLDVAIQRAKAGWLNRRALPWQERLLSGPLGKALLFRIVRKKTLAKTRGHYPAAERIIDVVRKGLDQGGPSGYEAEARAFGELAMSPQSAALRSLFFATTSLKKETGSAATARAIHRVGVLGGGLMGGGIANVTATRAGLPVRIKDINPQGINQALKYTWDALGKRVRSKRMRPTEQQRQMMLISGSTDYRGFERVDIVVEAVFEDLSLKQQMVADIERFGAAHTIFASNTSSLPISQIAALAQRPEQVIGLHYFSPVDKMPLVEVIPHEKTSEETIATTVALARKQGKTAIVVADRAGFYVNRILAPYINEAARCLLDGEPIESVDNALVDFGFPVGPMMLLDEVGIDVATKIMPILVEQLGPRFAAPPSFDVILKDGRKGRKNGRGFYLYSNPTKNSSPTKNGNSPAKRNSFKWRKNKVKPVDASIYTLLGVTPKAHLGAGVITQRCTMLMLNEAVRCLDESIIRNPRDGDIGAVFGIGFPPFLGGPFRYLDSLGADKVVQALRLLVQQYGERFEPCQRLVTMAEQQQQFYPVDANIDEVTDVAS
What is the function of this protein?
Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA.  Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGT_THIDA
Sequence: MKFDLLRTDGGARRGQLHLAHGVVQTPVFMPVGTYGTVKAMSPTEIADIGFEMLLSNTFHLWLRPGLEVIEAHGGLHRFMGWDKPILTDSGGFQVFSLGKLRKITEEGVKFASPTNGDKLFLTPETSMQIQRTLNSDIVMIFDECTPYPATERQAADSMRMSLRWAARSKAAHAGNPNALYGIVQGGMYEALRDESARELIGMDFDGYAIGGLSVGEPKDDMTRILAHTAPQLPADKPRYLMGVGTPSDLVAAVAAGIDQFDCVLPTRNARHGILFTRRGEIRIRNARWKLDTAPIDEECDCYACRHFTRAYVHHLIRAGEILGARLTTLHNLHYYHRLMAEVRAAIDAQRFSEFVARFHATQALGW
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: NUCS_MYCSJ
Sequence: MRLVIAQCTVDYVGRLTAHLPSARRLLLIKSDGSVSVHADDRAYKPLNWMSPPCRLSEESGDPHPVWVVENKTGEQLRITVEEIEHDSSHDLGVDPGLVKDGVEAHLQKLLAEHVELLGAGYTLVRREYMTAIGPVDLLCRDETGRSVAVEIKRRGEIDGVEQLTRYLELLNRDTLLAPVSGVFAAQQIKPQARTLANDRGIRCLILDYDQMRGMDSDEYRLF
What is the function of this protein?
Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
What are the official names of this protein?
Endonuclease NucS.
What is the protein family that this protein belongs to?
Belongs to the NucS endonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_HYDCU
Sequence: MQSPVINELIDAFKLLPTIGPKSAQRLAYFLLQNHQQDGHRLASAIESALEKVGYCQQCRNLSETEICGFCASKSRQTDQLCIVETPTDVVAIEQSGIYKGQYFVLMGHLSPIDGIGPDELGLPILRDRLAQGEIQELILATNPTVEGEATAHYIQQMAIEFNISVTRLAQGIPLGGELEYIDSGTLGQAFAGRKAV
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: Y1354_MYCBO
Sequence: MPSEKATTRHLPGAVETLSPRTGRRPETPAYGSWLLGRVSESPRMRRVRIQGMLTVAILVTNVIGLIVGAMLLTVAFPKPSVILDAPHWVSFGIVPGYCVLAFILGTYWLTRQTARALRWAIEERTPSHDEARSAFLVPLRVALAVLFLWGAAAALWTIIYGLANRLFIPRFLFSMGVIGVVAATSCYLLTEFALRPMAAQALEVGATPRSLVRGIVGRTMLVWLLCSGVPNVGVALTAIFDDTFWELSNDQFMITVLILWAPLLIFGFILMWILAWLTATPVRVVREALNRVEQGDLSGDLVVFDGTELGELQRGFNRMVEGLRERERVRDLFGRHVGREVAAAAERERPKLGGEERHVAVVFVDIVGSTQLVTSRPAAEVVMLLNRFFTVIVDEVNHHRGLVNKFQGDASLAVFGAPNRLSHPEDAALATARAIADRLASEMPECQAGIGVAAGQVVAGNVGAHERFEYTVIGEPVNEAARLCELAKSYPSRLLASSQTLRGASENECARWSLGETVTLRGHDQPIRLASPVQQLQMPAQSADIVGGALGDHQTHTIYRGAHPTD
What are the official names of this protein?
Uncharacterized protein Mb1354c.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL3_DEBHA
Sequence: MSHRKYEAPRHGSLGFLPRKRSANIRGRVKSFPKDVKSKPVALTAFLGYKAGMTTVVRDLDRPGSKMHKREIVEAATVVDTPPLVVVGVVGYVETPRGLRSLTTVWAEHLSEEVRRRFYKNWYKSKKKAFTKYSAKYAQDGAQVERELARIKKYASVVRVLAHTQIKKTPLAQKKAHLAEIQVNGGSVSDKVDWAKEHFEKTVSVDSVFEKDEMVDVAAVTKGHGFEGVTHRWGTKKLPRKTHRGLRKVACIGAWHPANVQWTVARAGQNGFHHRTSINHKVYRVGSAGDESSGATEFDRTKKTINPMGGFVRYGNVKNDFMLLKGSIPGVKKRIVTIRKSLYVDTSRRATENVNLKWIDTASKFGKGRFQTPAEKHAFLGTLKKDLEK
What are the official names of this protein?
60S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDNF_MOUSE
Sequence: MRCISPTALVTFCAGFCISNPVLAQGLEAGVGPRADCEVCKEFLDRFYNSLLSRGIDFSADTIEKELLNFCSDAKGKENRLCYYLGATTDAATKILGEVTRPMSVHIPAVKICEKLKKMDSQICELKYGKKLDLASVDLWKMRVAELKQILQRWGEECRACAEKSDYVNLIRELAPKYVEIYPQTEL
What is the function of this protein?
Trophic factor for dopamine neurons.  Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons.  When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra (By similarity).
What are the official names of this protein?
Cerebral dopamine neurotrophic factor, ARMET-like protein 1, Conserved dopamine neurotrophic factor.
What is the protein family that this protein belongs to?
Belongs to the ARMET family.
What are the subcellular locations of this protein?
Secreted.
Protein: FAP_CHLVA
Sequence: MASITSRASARASCSQANTRAGRVALSGGALLRPARPARSFVPARKQQQGAVRRGGALSARASAVEDIRKVLSDSSSPVAGQKYDYILVGGGTAACVLANRLSADGSKRVLVLEAGPDNTSRDVKIPAAITRLFRSPLDWNLFSELQEQLAERQIYMARGRLLGGSSATNATLYHRGAAGDYDAWGVEGWSSEDVLSWFVQAETNADFGPGAYHGSGGPMRVENPRYTNKQLHTAFFKAAEEVGLTPNSDFNDWSHDHAGYGTFQVMQDKGTRADMYRQYLKPVLGRRNLQVLTGAAVTKVNIDQAAGKAQALGVEFSTDGPTGERLSAELAPGGEVIMCAGAVHTPFLLKHSGVGPSAELKEFGIPVVSNLAGVGQNLQDQPACLTAAPVKEKYDGIAISDHIYNEKGQIRKRAIASYLLGGRGGLTSTGCDRGAFVRTAGQALPDLQVRFVPGMALDPDGVSTYVRFAKFQSQGLKWPSGITMQLIACRPQSTGSVGLKSADPFAPPKLSPGYLTDKDGADLATLRKGIHWARDVARSSALSEYLDGELFPGSGVVSDDQIDEYIRRSIHSSNAITGTCKMGNAGDSSSVVDNQLRVHGVEGLRVVDASVVPKIPGGQTGAPVVMIAERAAALLTGKATIGASAAAPATVAA
What is the function of this protein?
Catalyzes the decarboxylation of free fatty acids to n-alkanes or n-alkenes in response to blue light (PubMed:28860382, PubMed:30106504, PubMed:30673222).  Substrate preference is toward fatty acids with C16 or C17 chains (PubMed:28860382, PubMed:30106504, PubMed:30673222).  Saturated fatty acids are converted to alkanes, not alkenes (PubMed:28860382).  The decarboxylation is initiated through electron abstraction from the fatty acid by the photo-excited FAD (PubMed:28860382).
What are the official names of this protein?
Fatty acid photodecarboxylase, chloroplastic, CvFAP.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: VSPUI_GLOUS
Sequence: VIGGVECNINEHRFLVALYTSRSRRFYCGGTLINQEWVLTAAHCDRKNIRIKLGMHSEKVPNEDAQTRVPKEKFFCLSSKTYTKWDKDIMLMRLKRPVNNSTHIAPVSLPSNPPSVGSVCRVMGWGTITSSQETHPDVPHCANINILDYEVCRAAYPELPVTRRTLCAGILEGGKDSCNGDSGGPLICNGQFQGIAYWGADTCAQPREPGLYTKVFDYTDWIQSIISGNTDATCPQ
What is the function of this protein?
Snake venom serine protease that may act in the hemostasis system of the prey.
What are the official names of this protein?
Snake venom serine protease ussurin, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPE_DESVH
Sequence: MEKSLHLEIVTPDKLVLSEQVDYVGAPGFEGEFGVLPSHIPFLSALAIGSLYYKANGKTHHVFVSGGFAEVSDNKVTVLAESAERAEDIDIDRARKAKDRAEQRLAQIKEKVDHARAQAALQRALARMRVRGNA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SSRB_HUMAN
Sequence: MRLLSFVVLALFAVTQAEEGARLLASKSLLNRYAVEGRDLTLQYNIYNVGSSAALDVELSDDSFPPEDFGIVSGMLNVKWDRIAPASNVSHTVVLRPLKAGYFNFTSATITYLAQEDGPVVIGSTSAPGQGGILAQREFDRRFSPHFLDWAAFGVMTLPSIGIPLLLWYSSKRKYDTPKTKKN
What is the function of this protein?
TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.
What are the official names of this protein?
Translocon-associated protein subunit beta, TRAP-beta, Signal sequence receptor subunit beta, SSR-beta.
What is the protein family that this protein belongs to?
Belongs to the TRAP-beta family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: TDH_STRAW
Sequence: MKALVKEKAEPGLWLMDVPEPEIGPGDVLIKVLRTGICGTDLHIRSWDGWAQQAVRTPLVLGHEFVGEVVETGRDVVDIKAGDRVSGEGHLVCGKCRNCQAGRRHLCRATVGLGVGRDGAFAEYVALPAANVWVHRVPVDLDVAAIFDPFGNAVHTALSFPLVGEDVLITGAGPIGLMAAAVARHAGARNVMITDVSEERLELARKIGVSLALNVADTTIADGQRALGLREGFDIGLEMSGRPEAMRDMIANMTHGGRIAMLGLPSQEFPVDWARIVTSMITIKGIYGREMFETWYAMSVLLEGGLDLAPVITGRYGYRDYEAAFADAASGRGGKVILDWTL
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HFLD_SHEAM
Sequence: MSQMQARTMAFAGILQALAQVQYIARHGDSDTDAMAASFNTIMVTNPEQPEDVYADKDQLRVGYKWILNQLGDGESKDVEMTRYLVGLLALERKLSRSNAALGMLSERINQIHRQLNHFAITDEQVIANLASIYSDIISNLGPKLQITGNPNVLQRPLVQQKIRALLLAAMRSAVLWRQLGGKRRHLVFARKAIVDTAKKNLTL
What are the official names of this protein?
High frequency lysogenization protein HflD homolog.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PXPA_BACP2
Sequence: MYQVDINCDLGESFGQYTIGSDEQILEYVTSANIACGFHAGDPTVMRKTVRMALEKGVQIGAHPGLQDLVGFGRRPIAISAEEAYDLVVYQIGALSAFLKAEGSTMQHVKPHGALYNMAAKNTELSESIAKAVYHVDPSLVLYGLSGSELALAGERMGLQVAHEVFSDRTYQTDGTLTSRREPNALIEDDELAVQQVVRMVREGKVHTVQGEDISLKADTVCIHGDGIHALQFAKTITSKLKEASIRLKAFQ
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: DNJC5_MOUSE
Sequence: MADQRQRSLSTSGESLYHVLGLDKNATSDDIKKSYRKLALKYHPDKNPDNPEAADKFKEINNAHAILTDATKRNIYDKYGSLGLYVAEQFGEENVNTYFVLSSWWAKALFVVCGLLTCCYCCCCLCCCFNCCCGKCKPKAPEGEETEFYVSPEDLEAQLQSDEREATDTPIVIQPASATETTQLTADSHPSYHTDGFN
What is the function of this protein?
Acts as a co-chaperone for the SNARE protein SNAP-25 (PubMed:22187053).  Involved in the calcium-mediated control of a late stage of exocytosis (PubMed:20847230).  Acts as a general chaperone in regulated exocytosis (By similarity).  May have an important role in presynaptic function (By similarity).  May be involved in calcium-dependent neurotransmitter release at nerve endings (By similarity).
What are the official names of this protein?
DnaJ homolog subfamily C member 5, Cysteine string protein, CSP, Cysteine-string protein isoform alpha.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Membrane; Lipid-anchor. Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane. Melanosome. Cell membrane. Note=The association with membranes is regulated by palmitoylation (By similarity). Colocalizes with insulin granules, when overexpressed in an islet cell line (PubMed:17034881).
Protein: ISPG_SHEPC
Sequence: MYNETPIKRRPSTRIYVGNVPIGDGAPIAVQSMTNTKTTDVEATIAQIRALEKVGADIVRVSVPTMDAAEAFKIIKQSVNVPLVADIHFDYRIALKVAEYGVDCLRINPGNIGNEERIRSVVECARDKNIPIRIGVNGGSLEKDLMDKYKEPTPEALLESAMRHVDILDRMNFDQFKVSVKASDVFLAVESYRLLAKQIRQPLHLGITEAGGARAGSVKSAVGLGMLLAEGIGDTLRISLAADPVEEIKVGFDILKSLRIRSRGINFIACPSCSRQEFDVISTVNELERRLEDVTTAMDVSIIGCVVNGPGEALVSHIGLTGGHNKSGYYDEGERQKERFDNDNLVDSLEAKIRAKASQLANRIQVKDTTE
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: RECA_SHIB3
Sequence: MAIDENKQKALAAALGQIEKQFGKGSIMRLGEDRSMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDPIYARKLGVDIDNLLCSQPDTGEQALEICDALARSGAVDVIVVDSVAALTPKAEIEGEIGDSHMGLAARMMSQAMRKLAGNLKQSNTLLIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRIGAVKEGENVVGSETRVKVVKNKIAAPFKQAEFQILYGEGINFYGELVDLGVKEKLIEKAGAWYSYKGEKIGQGKANATAWLKDNPETAKEIEKKVRELLLSNPNSTPDFSVDDSEGVAETNEDF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMU_GLAP5
Sequence: MTQLSVVILAAGKGTRMYSDLPKVLHPIAGKPMVKHVIDTAKQLSAKQIHLIYGHGGDLLQQRLSAEPVNWVLQAEQLGTGHAMQQAAPFFADDENILMLYGDAPLITATTLEKLIAAKPENGIALLTVVLDNPTGYGRIIRENGSVVAIVEQKDANPEQLKIQEINTGVMVASGASFKKWLSQLDNNNAQGEYYITDVIAMANRDGYKVEAVQATNLMEVEGANNRLQLAALERYYQKIQAEKLLLAGVTIIDPARFDLRGTVTHGKDVVIDVNVILEGSIQLGNNVKIGAGSVLKNVVLGDNVEIKPYSVLEDSVIGESADVGPFARLRPGTELAAKAHVGNFVEIKKSTIGEGSKVGHLTYIGDSEIGANVNIGAGTITCNYDGANKFKTIIGDNVFVGSDTQLVAPVTVASGATIGAGSTITKDVAADELVITRVPQRHIQGWQRPTKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CARA_PYRFU
Sequence: MGVHKKGYLVLEDGSVIEGKAFGAETIRYGEVVFTTAMVGYPESLTDPSYKGQILIATNPLMGTYGVSSKSLKEHGLPLHYESDSIKVEGFVISFLMRPNHWSSEMTLDEWLRREGVPGLYGVDTRALVKKIREEGVMRGAIVTTETDLEEILENIRKISYESTNFVELVSPKNPIVHTPKNVKFRVVVLDLGVKFGILRELLKRGIEVVRIPWNWDILEAYYSYNADGIFISNGPGNPTLLKEVAKRIRKAFNEEIPMMGICLGQQLLALADGAEIYKLKYGHRGINKPVKDLESGKAFVTTQNHGYAIVPESLNEFKVWMVNLDDNSVEGIKHESLPIIATQYHPEASPGPWDSLWVFDEFVKILEGRK
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: RL5_SHEB2
Sequence: MAKLHDKYQETVVAELAKKFGYTSVMQVPRIEKITLNMGVGEAVADKKIMDHAVRDMTAIAGQKPVVTVARKSVAGFKIREGYPIGCKVTLRGERMWEFLERLVDIAIPRIRDFRGLSAKAFDGRGNYAMGVREQIIFPEIDYDKIDKIRGMDIVITTTAKNDEEGRALLDAFNFPFKK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: NDHJ_SYNJB
Sequence: MAEENAQEKQAPPSAGEQSEPLVTLERGPVSQFLADNGFEHQYLGRDAAGVELLEVERDFLLPLCTALYAYGFNYLECQCGYDLGAGQPLVSLYHLIKLSDGADRPQEVRLQVKLPRQDPRLPSVYWIWKSADWQERETYDMYGIVFEGHPNLKRILMPEDWIGWPLRKDYITPDFYELQDAY
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit J, NAD(P)H dehydrogenase subunit J, NADH-plastoquinone oxidoreductase subunit J, NDH-1 subunit J, NDH-J.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MUTS_LACP3
Sequence: MPQKTSETPMMQQYNEIKAQYPDAFLFYRIGDFYELFNDDAIKGAQLLELTLTARNKSADDPIPMAGVPHHAVQSYVDILIDHGYKVAICEQMEDPKKAVGMVKRAVIQLVTPGTNVDIKAGAAKSNNYITAVMPHAAGYAFAYADVSTGELKVTDLKSKFALQNELSALATKEIVVPEELTDDDAGMLKQGERLLSVQPDAEPTSEGSYVSQALTDPAEAAVVQMLMAYLLNTQKRSLAHIQKAVAYQPSAYLEMDQDARSNLDILQNSRTGRKGDTLLSLLDSTKTAMGGRLLKQWLDRPLLDIDAISVRQNQVQDLLDHFFERSELQERLTKVYDLERLAGRVAFGTVNGRDLIQLQTSLDQIPAIQDVLGKLDDGSFKALRSKMDPVSDVAGLIRRAIEPEPPISVTDGGLILRGYNQKLDSYRDAMKNSKQWIAELEASERKATGIHTLKIRYNKVFGYFIEVTKSNLDKIPEGRYERKQTLTNAERFITPELKEKETLILEAQESSTALEYDLFQDIRDKVKAQIKRLQALAAQISSLDVLQSFATVAENSHYVRPTMHAGTHDINVKGGRHPVVEHVLGRDSYIPNDVIMNHDTDMLLITGPNMSGKSTYMRQLALIVIMAQAGSFVPADVADLPIFDQIFTRIGAADDLANGESTFMVEMLEANAALSHATASSLILFDEIGRGTATYDGMALAQAIIEFLHDHVHAKTLFSTHYHELTSLSDSLAKLKNVHVGAVEEHGNLVFLHKMMPGPADKSYGIHVAKLAGLPADLLARADTILKQLEADAPNKTAPAPAPQVEEQQLSLFEEPKPTPKNSPILTKLAKFDLMAATPMDAMNFIFDLQKHLKKK
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: RL10_DROME
Sequence: MGRRPARCYRYCKNKPYPKSRFCRGVPDPKIRIFDLGRKKATVEDFPLCVHLVSDEYEQLSSEALEAGRICCNKYLVKYCGKDQFHIRMRLHPFHVIRINKMLSCAGADRLQTGMRGAFGKPQGTVARVRIGQPIMSVRSSDRYKAQVIEALRRAKFKFPGRQKIYVSKKWGFTKYERERYEELRDDNRLEPDGCNVKYRPEHGPIAAWEKAQRDVYA
What are the official names of this protein?
60S ribosomal protein L10, QM protein homolog, dQM.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: RLMH_XANAC
Sequence: MKCRLIATGERAPSWVAQGFAEYQKRLSHWMPLELVEIEPGMRGKGRDAQRATDDEGRRVLAALPKNAYVVALDVPGRPLSSEQLAQRMEHWRGQGRDLAFLIGGPEGHAAEVLKSASESWSIGPLTLPHMLVRLIVAEQLYRAAAMLANHPYHRA
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXD_CHLAB
Sequence: MPQELVYTLQQLADLLKVEVQGNTETPISGVEEISAAKAHHVTFLDNEKYARFIKITEAGAIILSKAQAQKYGHLNKNFLIVSEFPSIAFQKCIELFISPVDSGFPGIHPTAVIHPTASIGKDVCIEPYAVICQHACIGDSTYIGTGSVIGAYSTLGEHCLVHPKVVVRERVEIGKRVIIQPGAVIGSCGFGYITNAFGRHKHLKHLGKVIIEDDVEIGANTTIDRGRFKNSVIREGTKIDNQVQIAHHVEVGKHSMIVAQAGIAGSTKIGNHVIIGGQTGITGHISITDHVIMMAQTGVTKSISSPGIYGGAPARPYQEIHRQVAKIRSLPKLEERLGMLEEKVKGLSAQSTELQITP
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.