PharMolix/UniProtQA huggingface dataset:
Protein: MLP3B_HUMAN
Sequence: MPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESEKDEDGFLYMVYASQETFGMKLSV
What is the function of this protein?
Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes) (PubMed:20418806, PubMed:23209295, PubMed:28017329).  Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production (PubMed:23209295, PubMed:28017329).  In response to cellular stress and upon mitochondria fission, binds C-18 ceramides and anchors autophagolysosomes to outer mitochondrial membranes to eliminate damaged mitochondria (PubMed:22922758).  While LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (PubMed:20418806, PubMed:23209295, PubMed:28017329).  Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway (PubMed:24089205).  Through its interaction with the reticulophagy receptor TEX264, participates in the remodeling of subdomains of the endoplasmic reticulum into autophagosomes upon nutrient stress, which then fuse with lysosomes for endoplasmic reticulum turnover (PubMed:31006537, PubMed:31006538).  Upon nutrient stress, directly recruits cofactor JMY to the phagophore membrane surfaces and promotes JMY's actin nucleation activity and autophagosome biogenesis during autophagy (PubMed:30420355).
What are the official names of this protein?
Microtubule-associated proteins 1A/1B light chain 3B, Autophagy-related protein LC3 B, Autophagy-related ubiquitin-like modifier LC3 B, MAP1 light chain 3-like protein 2, MAP1A/MAP1B light chain 3 B, MAP1A/MAP1B LC3 B, Microtubule-associated protein 1 light chain 3 beta.
What is the protein family that this protein belongs to?
Belongs to the ATG8 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Endomembrane system; Lipid-anchor. Mitochondrion membrane; Lipid-anchor. Cytoplasm, cytoskeleton. Cytoplasmic vesicle. Note=LC3-II binds to the autophagic membranes. LC3-II localizes with the mitochondrial inner membrane during Parkin-mediated mitophagy (PubMed:28017329). Localizes also to discrete punctae along the ciliary axoneme.
Protein: FAA10_MYCTO
Sequence: MGGKKFQAMPQLPSTVLDRVFEQARQQPEAIALRRCDGTSALRYRELVAEVGGLAADLRAQSVSRGSRVLVISDNGPETYLSVLACAKLGAIAVMADGNLPIAAIERFCQITDPAAALVAPGSKMASSAVPEALHSIPVIAVDIAAVTRESEHSLDAASLAGNADQGSEDPLAMIFTSGTTGEPKAVLLANRTFFAVPDILQKEGLNWVTWVVGETTYSPLPATHIGGLWWILTCLMHGGLCVTGGENTTSLLEILTTNAVATTCLVPTLLSKLVSELKSANATVPSLRLVGYGGSRAIAADVRFIEATGVRTAQVYGLSETGCTALCLPTDDGSIVKIEAGAVGRPYPGVDVYLAATDGIGPTAPGAGPSASFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLERREDGFFYIKGRSSEMIICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEFGALVGLAVVASAELDESAARALKHTIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATADKARVVVRG
What is the function of this protein?
Catalyzes the activation of medium/long-chain fatty acids as acyl-adenylates (acyl-AMP), which are then transferred to the phosphopantetheine arm of the acyl carrier protein (ACP) MT0109.
What are the official names of this protein?
Medium/long-chain-fatty-acid--[acyl-carrier-protein] ligase FadD10.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOHO_SHISS
Sequence: MRIAKIGVIALFLFMALGGIGGVMLAGYTFILRAG
What are the official names of this protein?
UPF0387 membrane protein YohO.
What is the protein family that this protein belongs to?
Belongs to the UPF0387 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: UR2R_MACMU
Sequence: MALTPESPSSFPGLAAIGSSVPEPPGSPNATLNSSWASPTEPSSLEDLVATGAIGTLLSAMGVVGVVGNAYTLVVTCRSLRAVASMYIYVVNLALADLLYLLSIPFIVATYITKEWHFGDVGCRVLFSLDFLTMHASIFTLTVMSSERYAAVLRPLDTVQRPKGYRKLLALGTWLLALLLTLPVMLAMRLVRRGPKSLCLPAWGPRAHRAYLTLLFATSIAGPGLLIGLLYARLARAYRRSQRASFKRARRPGARALRLVLGIVLLFWACFLPFWLWQLLAQYREAPLAPRTARIVNYLTTCLTYGNSCANPFLYTLLTRNYRDHLRGRVRSPGSGGVRGPVPSLQPRARFQRGSGRSLSSCSPQPTESLVLAAAAPAGPALESPGDPA
What is the function of this protein?
High affinity receptor for urotensin-2 and urotensin-2B.  The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system (By similarity).
What are the official names of this protein?
Urotensin-2 receptor, UR-2-R, Urotensin II receptor, UR-II-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FOSB_STAA1
Sequence: MLKSINHICFSVRNLNDSIHFYRDILLGKLLLTGKKTAYFELAGLWIALNEEKDIPRNEIHFSYTHIAFTIDDSEFKYWHQRLKDNNVNILEGRVRDIRDRQSIYFTDPDGHKLELHTGTLENRLNYYKEAKPHMTFYK
What is the function of this protein?
Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin.  L-cysteine is probably the physiological thiol donor.
What are the official names of this protein?
Metallothiol transferase FosB, Fosfomycin resistance protein.
What is the protein family that this protein belongs to?
Belongs to the fosfomycin resistance protein family. FosB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IFTAP_HUMAN
Sequence: MSAHMSGLEIMDEDQLIKDVLDKFLNCHEQTYDEEFLNTFTHLSQEDHVSKRGVFGTDSSENIFTSAKVTHKNEADDYHLRNKTIFLRTSSQCLEEQVDNFLDLEDLDMDEEIKPQMSEDLLLLPGEVEQDVSTSIPSCIPFVAQPPTCEVKPKPSVKRMDKQTEEILGDEVQLFSLDEEFDYDNVMLTSKFSPAEIENIKELCKQQKRKDTSPDLEKSCD
What is the function of this protein?
Seems to play a role in ciliary BBSome localization, maybe through interaction with IFT-A complex.
What are the official names of this protein?
Intraflagellar transport-associated protein, Protein HEPIS.
Protein: TRAR2_HUMAN
Sequence: MACPGFLWALVISTCLEFSMAQTVTQSQPEMSVQEAETVTLSCTYDTSESDYYLFWYKQPPSRQMILVIRQEAYKQQNATENRFSVNFQKAAKSFSLKISDSQLGDAAMYFCAYRSAVNARLMFGDGTQLVVKPNIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKTVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFPSPESSCDVKLVEKSFETDTNLNFQNLSVIGFRILLLKVAGFNLLMTLRLWSS
What is the function of this protein?
The alpha chain of TRAV38-2DV8*01J31*01C*01/TRBV25-1*01J2S3*01C2*01 alpha-beta T cell receptor (TR) clonotype that displays pan-cancer cell recognition via the invariant MR1 molecule.  On CD8-positive T cell clone MC. 7. G5, likely recognizes tumor-specific or -associated metabolite(s) essential for cancer cell survival, triggering killing of many cancer cell types including lung, melanoma, leukemia, colon, breast, prostate, bone and ovarian cancer cells.  Mediates cancer cell cytotoxicity in an HLA-independent manner.  Has no reactivity to healthy cells, even stressed or infected by bacteria (PubMed:31959982).  Antigen recognition initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.  In turn, ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.  The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell differentiation into effector/memory T cells (By similarity).
What are the official names of this protein?
T cell receptor alpha chain MC.7.G5, MC.7.G5 TRA, TR alpha chain TRAV38-2DV8*01J31*01C*01.
What are the subcellular locations of this protein?
Cell membrane.
Protein: CHM1B_DANRE
Sequence: MSSMEKHLFNLKFAAKELQRNSKKCDKEEKAEKVKVKKAIQKGNMEVARIHAENAIRQKNQSVNFLRMSARVDAVAARVQTAVTMNQVTKSMAGVVKGMDATLKSMNLEKISGLMEKFERQFETLDVQTAQMEDSMSSTTTLTTPQGQVDTLMMEMADEAGLDLNMELPQGQTGSVGTSVASAEQDELSQRLAKLRDQV
What is the function of this protein?
Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs.  MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids.
What are the official names of this protein?
Charged multivesicular body protein 1b, Chromatin-modifying protein 1b, CHMP1b.
What is the protein family that this protein belongs to?
Belongs to the SNF7 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Endosome. Late endosome membrane; Peripheral membrane protein.
Protein: YGBA_SCHPO
Sequence: MSESAPAGSKEGVSFGNLPRPEPRTSKDQQKLSISTDVKKPSHSAPVTPVRSARSSMEQPTFRPVAKNSVTVAPARAAGFCPPQFEEYHHGRSHSLVSPPPSPHFLKRISFDTFNNKAATDFSLTLKTQHQAYKWTRTSRTFLCGMDGNSYSEVAVDWLFETLLADNDEAVVLRVIDPSSKLAEDLSDEQSYRSLAEHIMAGILKKVDDDKAVSIIVELVVGKPQDMILRTIHVYSPDSLIVGTRGKALNSFQSLLSSGSVSKFCLQKSPIPVIVVRPDRKRVRSKNKRLKDKTRKSYMEILEKSGR
What are the official names of this protein?
Universal stress protein A family protein C25B2.10.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein A family.
What are the subcellular locations of this protein?
Barrier septum. Cell tip.
Protein: LT4R1_RAT
Sequence: MAANTTSTAATSSPGGMSLSLLPIVLLSVALVVGLPGNSFVVWSILKRMQKRSVTALLVLNLALADLAVLLTAPFFLHFLARGTWSFEVTGCRLCHYVCGVSMYASVLLITIMSLDRSLAVARPFVSQKVRTKAFARWVLAGIWVVSFLLAIPVLVYRTVTPKNKTLICDSRYPSDGHKVFHLLFEAITGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILAFAAFWLPYHLVNLVEAGRTLAGWDKNSPAGQRLKLARYVLIALAFLSSSVNPVLYACAGGGLLRSAGVGFVVKLLEGTGSEVSSTRRGGTLVQTPKATPTCPEPGPTDSFMTSSTPPESSK
What is the function of this protein?
Receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.
What are the official names of this protein?
Leukotriene B4 receptor 1, LTB4-R 1, LTB4-R1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LONM_YEAST
Sequence: MLRTRTTKTLSTVARTTRAIQYYRSIAKTAAVSQRRFASTLTVRDVENIKPSHIIKSPTWQEFQHQLKDPRYMEHFAQLDAQFARHFMATNSGKSILAKDDSTSQKKDEDVKIVPDEKDTDNDVEPTRDDEIVNKDQEGEASKNSRSSASGGGQSSSSRSDSGDGSSKQKPPKDVPEVYPQMLALPIARRPLFPGFYKAVVISDERVMKAIKEMLDRQQPYIGAFMLKNSEEDTDVITDKNDVYDVGVLAQITSAFPSKDEKTGTETMTALLYPHRRIKIDELFPPNEEKEKSKEQAKDTDTETTVVEDANNPEDQESTSPATPKLEDIVVERIPDSELQHHKRVEATEEESEELDDIQEGEDINPTEFLKNYNVSLVNVLNLEDEPFDRKSPVINALTSEILKVFKEISQLNTMFREQIATFSASIQSATTNIFEEPARLADFAAAVSAGEEDELQDILSSLNIEHRLEKSLLVLKKELMNAELQNKISKDVETKIQKRQREYYLMEQLKGIKRELGIDDGRDKLIDTYKERIKSLKLPDSVQKIFDDEITKLSTLETSMSEFGVIRNYLDWLTSIPWGKHSKEQYSIPRAKKILDEDHYGMVDVKDRILEFIAVGKLLGKVDGKIICFVGPPGVGKTSIGKSIARALNRKFFRFSVGGMTDVAEIKGHRRTYIGALPGRVVQALKKCQTQNPLILIDEIDKIGHGGIHGDPSAALLEVLDPEQNNSFLDNYLDIPIDLSKVLFVCTANSLETIPRPLLDRMEVIELTGYVAEDKVKIAEQYLVPSAKKSAGLENSHVDMTEDAITALMKYYCRESGVRNLKKHIEKIYRKAALQVVKKLSIEDSPTSSADSKPKESVSSEEKAENNAKSSSEKTKDNNSEKTSDDIEALKTSEKINVSISQKNLKDYVGPPVYTTDRLYETTPPGVVMGLAWTNMGGCSLYVESVLEQPLHNCKHPTFERTGQLGDVMKESSRLAYSFAKMYLAQKFPENRFFEKASIHLHCPEGATPKDGPSAGVTMATSFLSLALNKSIDPTVAMTGELTLTGKVLRIGGLREKAVAAKRSGAKTIIFPKDNLNDWEELPDNVKEGLEPLAADWYNDIFQKLFKDVNTKEGNSVWKAEFEILDAKKEKD
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix.  May also have a chaperone function in the assembly of inner membrane protein complexes.  Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome.  Binds to mitochondrial DNA in a site-specific manner (PubMed:15870080, PubMed:16428434, PubMed:8146662, PubMed:8276800, PubMed:8354406, PubMed:8810243, PubMed:9405361, PubMed:9724747, PubMed:35143841).  Endogenous substrates include ABF2, ACO2, ILV1, ILV2, LSC1, LYS4, MGM101 and several oxidized proteins.  The 2 nucleic acid-binding proteins ABF2 and MGM101 are protected from degradation by PIM1 when they are bound to DNA (PubMed:16428434, PubMed:20150421, PubMed:28377575).
What are the official names of this protein?
Lon protease homolog, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RL32_GEMAT
Sequence: MAVPKRRTSKRRKRARNTHKVAPAIVIQSCPQCSAAKRPHRVCAECGYYAGEQRVAAQEA
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: MQO1_STAAS
Sequence: MTTQHSKTDVILIGGGIMSATLGTLLKELSPEKNIKVFEKLAQPGEESSNVWNNAGTGHSALCELNYTKEGKDGTVDCSKAIKINEQYQISKQFWAYLVKTGQLDNPDRFIQAVPHMSFVIGEDNVAFIKSRVATLKKSVLFEKMKLSQDEEEMKSWVPLMIEGRKSDEPIALTYDETGTDVNFGALTAKLFENLEQRGVGIQYKQNVLDIKKQKSGAWLVKVKDLETNETTTYESDFVFIGAGGASLPLLQKTGIKQSKHIGGFPVSGLFLRCTNQEVIDRHHAKVYGKAAVGAPPMSVPHLDTRFVDGKRSLLFGPFAGFSPKFLKTGSHMDLIKSVKPNNIVTMLSAGIKEMSLTKYLVSQLMLSNDERMDDLRVFFPNAKNEDWEVITAGQRVQVIKDTEDSKGNLQFGTEVITSDDGTLAALLGASPGASTAVDIMFDVLQRCYRDEFKGWEPKIKEMVPSFGYRLTDHEDLYHKINEEVTKYLQVK
What are the official names of this protein?
Probable malate:quinone oxidoreductase 1, MQO 1, Malate dehydrogenase [quinone] 1.
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: Y7401_METNO
Sequence: MAGHSQFKNIMHRKGRVDAVRSKVFGKLAREITVAAKLGTPDPAMNPRLRAAVLAARAENMPKDNIERAIKKACGGDAETYEEIRYEGYGPGGAALIVEAQTDNRNRTASDVRSAFTKAGGSLAETGAVSFMFDRVGLVAFDAKVADADTMLEAAIEAGADDVKSDESGHEVTCEQSALGEVAKALEARFGEPRRTSLVWRPQNTVEVDDETGEKLIRLVEMIEDQDDVQNVFVNFAVSDALMAKLHD
What are the official names of this protein?
Probable transcriptional regulatory protein Mnod_7401.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXB_SALTY
Sequence: MAAQRPLTIALVAGETSGDILGAGLIRALKARVPNARFVGVAGPRMQAEGCEAWYEMEELAVMGIVEVLGRLRRLLHIRADLTRRFTELKPDVFVGIDAPDFNITLEGNLKKKGIKTIHYVSPSVWAWRQKRVFKIGRSTHMVLAFLPFEKAFYDKFNVPCRFIGHTMADAMPLDPDKNAARDVLGIPHDAHCLALLPGSRGAEVEMLSADFLKTAQLLRQRYPDLEVVVPLVNAKRREQFEKIKAEVAPDLAVHLLDGMAREAMIASDAALLASGTAALECMLAKCPMVVGYRMKPFTFWLAKRLVKTEYVSLPNLLAGRELVKELLQEECEPQKLAEALLPLLANGKTSHAMHDTFRELHQQIRCNADEQAADAVLELAQ
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: REC2_ARATH
Sequence: MAPKAGKTKPHKSKGEKKKKEEKVLPTVIEISVETPDESQVTLKGISTDRILDVRKLLAVHVQTCHFTNFSLSHQVRGTKLKDSVDIVSLKPCHLTIVEEDYTEEQATAHIRRLLDIVACTTAFGPSKPPVSRTLPKDSEKKESGSTDGDSPTEKDAGDSNSGLSPKPKESEKKSVGACEAQSAEGAAKSDIDMCPPTRLGQFYEFFSFSYLTPPIQYIRRSVRPSKEDKGLDDLFQIDIKVSSGKPFTVVASRTGFYPPGKQQLLCHSLVELLQQISRPFDAAYDALMKAFIEHNKFGNLPYGFRANTWVVPPVVADSPSTFPSLPVEDETWGGDGGGVGRSGKYDKRKWAKEFAILAAMPCKTPEERQVRDRKAFLLHSLFVDVSVFKAVEIIKKIVENNQCSLKDPAALGFHEERIGDLIVRVARDDPDASAKLDRKSDGTQVLEISQEELAQRNLLKGITADESATVHDTSTLGVVVVRHCGCTAIVKVASEFKLNDGHILQDIDIEDQSEGGANALNVNSLRTLLHKSSTPSSLAQRSPNADSEQIRVAKSLVRKVIEDSLKKLEIEPSRYSKPIRWELGACWVQHLQNQASSKSESKKTEDPKPEPAVKGLGKQGALLKEIKRKIDVKANKTEQGKEAPANDTDNTSETEDQKELEKQNEEIEKMWKELVTETAYQRLKESETGFHLKSPKELIEMARKYYTDTALPKLVADFGSLELSPVDGRTLTDFMHTRGLQMHSLGRVVELAEKLPHVQSLCVHEMIVRAYKHILQAVVAAVENTADVATSIATCLNVLLGTPSDTESVYDEKIKWTWVETFISKRFGWDWKHEGCQELRKFSILRGLSHKVGLELVPKDYEMDTSYPFKKFDIISMVPVYKHVACSSADGRTLLESSKTSLDKGKLEDAVNYGTKALAKLVAVCGPYHRMTAGAYSLLAVVLYHTGDFNQATIYQQKALDINERELGLDHPDTMKSYGDLAVFYYRLQHTELALKYVNRALYLLHLTCGPSHPNTAATYINVAMMEEGMKNAHVALRYLHEALKCNQRLLGADHIQTAASYHAIAIALSLMDAYSLSVQHEQTTLQILQAKLGPEDLRTQDAAAWLEYFESKALEQQEAARNGTPKPDASISSKGHLSVSDLLDYITPDSGIKARDAQRKARPKVKGKPGQSPGPVSEENQKDDEILSPAHLTGESSSDKENKSETKSEEKKVENFDLEQSKPQDQLKLVKPEATVHEDDDSDEGWQEAVPKNRFSSGRRTRPSLAKLNTNFMNVTQQPSRSRGKSTNFTSPRTSSNELSISVAGSTSSPASKMFVKSPLNKKQNNSSVVGERPVNDKSALASSACTEQINKPTPMLSPVSVKAGKLFSYKEVALAPPGTIVKIVAEQLPEETKAPQNLDAAKIAVDGPEKVNAQDAESENKHVATETEAENTDCNEQGRVVVGGSELTSSPKEIKNVEVEKAAEKAFPIETAVSNARPGKSKSAQMAEDSDTCLLNKSPTANDSNGSESVIGVKLQKDLCDAELKTVDGETENLPNGDSSPKSSVAADGEKQDACEAQKEMSKKLSASAPPYTPTTIPIFGSIAVPGFKDHGGILPSPLNMPPMLPINHVRRSTPHQSVTARVPYGPRLSGGGYNRSGNRVPRNKPSFPNSTESNGEANQFNGPRIMNPHAAEFIPSQPWVSNGYPVSPNGYLASPNGAEITQNGYPLSPVAGGYPCNMSVTQPQDGLVSEELPGAGSSEEKSGSEEESNNDKNAGEDDEAVGQETTDTPENGHSTVGEVETTSHETCDEKNGERQGGKCWGDYSDNEIEQIEVTS
What is the function of this protein?
Negatively regulates meristematic tissue proliferation by integrating developmental signals with carbon source availability (PubMed:21185286).  May act as the scaffold of a protein complex, which sequesters key factors that are required for the G2 to M transition in meristematic tissues (PubMed:21185286).  Together with REC2, REC3 and FMT/CLU, contributes to the establishment of the cellular volume devoted to the chloroplast compartment (PubMed:26862170).
What are the official names of this protein?
Protein REDUCED CHLOROPLAST COVERAGE 2, Protein TPR-domain suppressor of STIMPY.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol.
Protein: Y3815_HALS3
Sequence: MSGNPDDDRLEELRQRKKEQLKQQQQGGDAEREAQQQQAQQAEQQKQAMLKQNLTDGARKRLNTIRMSKPEFAEQAEQQVLALAQSGRVQGRIDEDQMKEILRELKPDSQSFNINRR
What are the official names of this protein?
DNA-binding protein OE_3815R.
What is the protein family that this protein belongs to?
Belongs to the PDCD5 family.
Protein: ZAR1_TAKRU
Sequence: MATYCDEPVDSYFYSSYNPYMGRYPRHRDAGWKYKSYLSHYGDTSEAFSNQQRAQLKSILSQINPKLTPRLRKANTKDVAVQVNPKRDASVQCSIGPRTLLVVKRELRRRRKLNPGPPGTPQKTEGEVRYPRTLAVYSPIAFRSVTSFLVETGKDRPAAEAQAEELPGEQPEQKGGENQAGEETNANLPEQRKPQSEDAQTAADAEGSKGKARVRFQFLEQKYGYYHCRECNLRWESAYVWCVQGTNKVYFKQFCRKCQKDFNPYRVEDITCHVCNKARCACAETQRHVDPKRPHRQDLCGRCKGKRLSCDSTFSFKYIV
What is the function of this protein?
mRNA-binding protein required for maternal mRNA storage, translation and degradation during oocyte maturation (By similarity).  Probably promotes formation of some phase-separated membraneless compartment that stores maternal mRNAs in oocytes: acts by undergoing liquid-liquid phase separation upon binding to maternal mRNAs (By similarity).  Binds to the 3'-UTR of maternal mRNAs, inhibiting their translation (By similarity).
What are the official names of this protein?
Zygote arrest protein 1.
What is the protein family that this protein belongs to?
Belongs to the ZAR1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMG8_DROAN
Sequence: MKDYYTWTYPDVPENVAQELLQLENSMVVVGIVGRSKCERANKMQAFGMSPPMEHTPADGQVQCYYKRGTSCIFLHFETTYDEPILHRMIEDSMADHQNAFDFDHFYEQMRSRFVRMMLLALHTCHIIVYVETGPTFDPTLVTVFQLLKFSREQHLKQFLPQMLRDTPAAKLGEKSRLCAPRILFLFENFPSDELKTRENVSAYEFQTEDNIYEMLRHHHIFTNSSPSSLVALPNNKQFVYFNAHEELHPDYLLKAIDCLNKTMFKPDMREEEEDLEILELAPFEGFCKPFGPPGERDVEAQQYKRQHTAWHFLQRHIQDALHGCFDEGSFKQLPHLGQFQLLSFPEWQGCMDTLTQLLVENAKDTNFETNNEEYKNFLLNFEDSLNYEKKFWAHLCELGLKKGISSYKSSAPANYGSATHRKLLAEATIAFEEEGRGPPAQAALARMAAICLKHWQDGRQQCEKLSLRSQPCTLPKDVPHDKHNSGVIHISSCNCGRTQGRREDPFNLRQANYDFYELIAQICNLCVKVKQYQFPIFEPSVSDYRAAAFDAAFPMLNTGKICTPQGEDENEDGETEEADEDTEEKEQAEGDNCSQQLSPTFGSDLNMSIAGFGASLNESQESSEQLSGSEHESPNSGTSSADTENELVLQIKEPARKESTPTGGFSTSTTEYLPGLVHTVSDFGLLPLFPSWSLACVGPSSIYSHNTGLQEHFQSGFLSGANFLLPWDVLLRLVHANKHHQQHHHNMHLQQHPGKKQQRWKKQGDRLSIKIFVGMEYECSRGHRFMMCAPDRVLRGGADIERDTCNKVVHSNMPLYYPCPCRSQSNYLAQLMRIHVVTPKAPVNIIVDPKVCVGKYTFTLGTIIPPRLSQSAYWILRLPFVYQGDNVMIAPPEKLDPDNPMAGGYLLPGMFGVAETDANMDLSNPSRMGSTAGTFIRI
What is the function of this protein?
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.  Probable component of kinase complex containing nonC and recruited to stalled ribosomes (By similarity).
What are the official names of this protein?
Nonsense-mediated mRNA decay factor SMG8, Protein smg-8 homolog.
What is the protein family that this protein belongs to?
Belongs to the SMG8 family.
Protein: ISPG_RUEST
Sequence: MSMNHIRPWRNIERRKSRQIHVGNVPVGGDAPIAVQTMTNTLTTDIKGTIAQVQAAADAGADIVRVSVPDEASARALKEIVRESPVPIVADIHFHYKRGIEAAEAGAACLRINPGNIGDEKRVAEVIKAARDHNCSIRIGVNAGSLEKHLLEKYGEPCPDAMVESGLDHIKILQDHDFHEFKISVKASDVFMSAAAYQMLADATDAPIHLGITEAGGLMSGTIKSAIGLGQLLWMGIGDTLRVSLSADPVEEVKVGFEILKSLGLRHRGVNIISCPSCARQGFDVIKTVETLEERLEHIKTPMSLSIIGCVVNGPGEALMTDVGFTGGGAGSGMVYLAGKASHKMSNDQMIDHIVEEVEKKAAALDAQAAEDMKAAE
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: MU174_SCHPO
Sequence: MLLKVSSCEPLVPIKQWIHTSQLDLSDSSSLVADLLYNIIKFNFSGLEDKRAIFTGYESIKRYTIGNEMFLQLAKDGFALPVSMSYGLFLEETDTLELRALPRSEGLHRGCEVLVLRLDSPNELKENIREWSSKFMNSKASQKQQMLSPETMQKVDLAGRASPRYQANDSWISKKRNAPLSSISQYANMPENYALNTKKSKISNENDTIFKANFQQNKYESLHAKQISASDLSLHQEFVSASIVQQPELNSLLTSQSKNSTPSESDSSSSESSSSVSDSSDLSSTSDSSSGDESSDTARQSSSDTISSNNVSVSVSLNTANEFSFPQGTFKAENEAVESEVAPSSSTPPTVEEISYLHYDEPSQYYFSSPSKLSSETTKVHRGCENTEKPSEEGKNFTTPLSDSVESENTWSNTLRSSVEDDNTGVSDDNKKSKLNAEFDGHVNNISVRPPGSGSSATKARNLRRKKARILKRLMQESNDTFSANESTVVANVPDSYLTKNDEEDSASLASLKVAPKYVSHPVSLSSNSFHTEFPIGSLMRFTVMDLNPVTCTPEISEKTGRVVDCSEEKVKIQLDLGDRLDLKFDVNGEVIRNRYGTTPDEELIEGIATYEWSSLSNVHKLELTN
What is the function of this protein?
Has a role in sporulation.
What are the official names of this protein?
Meiotically up-regulated gene 174 protein.
Protein: SSPI_BACAC
Sequence: MSFNLRGAVLANVSGNTQDQLQETIVDAIQSGEEKMLPGLGVLFEVIWKNADENEKHEMLETLEQGLKK
What are the official names of this protein?
Small, acid-soluble spore protein I, SASP I.
What is the protein family that this protein belongs to?
Belongs to the SspI family.
What are the subcellular locations of this protein?
Spore core.
Protein: TRMFO_SYNP6
Sequence: MAAISQPVIVIGAGLAGTEAAWQIAEAGVPVILYEMRPQRQSPAHHSESFAELVCSNSFGAMASDRAAGLLHEELRRLGSLVFSKASEHQVPAGGALAVDRALFSEDLTRTVADHPLVEIRREELRSLPTEGIVVLCTGPLTSPDLAEDLQRFTGQDYCSFFDAASPIVTGESIDQAIAFRASRYDKGEAAYLNCPLNRDQYLAFREALVTAEQAELKDFEQESAKFFEGCLPIEELARRGEDTMRYGPLKPVGLFDARLGDWRDPENRSRRPYAIVQLRQEDRAGNLWNLVGFQTNLRWGEQKRIFQMIPGLSQAEFVRFGVMHRNTFVNAPQLLDASLQFRQRPTLLAAGQLIGTEGYSAAVAGGWLAGTNAARLALGRSPLVLPDTLVSGSLFRFISSAEPKYFQPMPPNFGILPNLEQPPRNKKDRYAAYRDRALQDLRDWQQTHAIGNLSPSTGLATTAIA
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_NITOC
Sequence: MRRVRVGDEVIVTAGRSKGKQGKILRILGDERVIVQDVNMVKRHTRPNPTANKPGGIIEREASIHISNVMLYNPATEKGDRIGFRRLEDGRKVRYFKSNDEIIDV
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.