PharMolix/UniProtQA huggingface dataset:
Protein: MURG_CUTAK
Sequence: MVNVVLAGGGTAGHTSPLIATAMALQERGATVSCIGTPRGLEGRVIPEAGLQLDMIPPVPLPRTVNADLFKVPARLAGAVRKAGEVLQRRQTDVVVGFGGYVSLPAYLAARRAKIPVVIHEQNAVPGLANKIAARFAVFVGTAFPDTPLPKARFVGMPLRSQITDLADASGQARAERCARARADLGLDINRPTLLVSGGSQGAVAINEAVVAARTRLLADGVQILHVLGPKNIRGATRITDELTGASWLPMGYVDDMASAYAAADLMVARSGAGTVVETATVGLPTIYVPLPHGNGEQARNATSAVDAGAGVVVANADLDVERLLAETARIHDADVLAQMSAAGRGLMPAHAAEEMAVRVISAATSIDPTIG
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SYA_XANC5
Sequence: MNAPAKFSTSQIRSDFLAFFEGKGHTIVPSAPLVPGNDPTLLFTNSGMVQFKDVFLGAEKRSYVRAADVQRCLRAGGKHNDLDSVGYTARHHTFFEMLGNWSFGDYFKKDAIAWAWELLTQVWKLPADRLLVTVYHTDEEAFALWRDMIGIPESRIVRIGDNKGAPYASDNFWQMADTGPCGPCTEIFFDHGDHIAGGPPGSPDEDGDRFIEIWNLVFMQFDRQPDGTLVPLPAPCVDTGMGLERLAAILQHVHTNYEIDLFQALIGKASALTGITDLENKSLRVIADHIRACSFLIVDGVLPSNEGRGYVLRRIIRRALRHGWMLGVRQPFFSKMVPTLVELMGEAYPELVVAQDTVARALLAEEERFAETLDAGMKIFDEVASRSQDIIPGADAFRLYDTYGFPVDLTADIARERGMRVDMEGFEFAMERQRETARAAGKFGGGVALPADLVASMSPTVFLGYEAYDADALKVVALLKQGRPVERAEAGDEVIVFTDRTPFYAESGGQVGDSGQLSGPGVSINVTDTQKFAGQFHGHVGRISEGALALGDVLAGGIDTQRRGKTILNHSATHLLHAALREVLGTHVQQKGSLVAPDRLRFDFSHFQPFTADELAVIERKVNAEVRANHGVEVHNMAMQEALDFGAMALFGEKYGENVRVLKMGGYSTELCGGTHVTRTGDIGLFKITSEGGVSSGVRRIEAVTGQGALDYVADEERRLLEAANLLGGNTSEVVDKVRALTERQKRLERELESLKAKLASGATADLGASAIDVVGVKVVAVRLEGFDAKALRDAMDRLKQQLGDSVIVLAGASGGKVALVAGVNGSPTGKVKAGELLGHIASQIGGKGGGRPDLAQGGGEDGPALATALDGVPLWVKQHLG
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1923_AQUAE
Sequence: MKKALGILAILLILVGGYFAYDKYMDNKAKEQVEYFLDKTLRKSGKGSYKYVDYKPIGGEIIIKDVYYRDRNGEEFKIEEIIIEKLSETEGKFLFKNVKPLKVKGKGLLEEYGYKDPKFNLFVSYEAKPKEKEFHLRSLSLDYPEAFEVNISFILGNYDHAFWKTVALSDRPPEEVSFQVLSELGSIKINSLEVVYRDKGFKERVIKKEAQKRGKTPEEFKKELIRKIEEEKLKARSEFERNLLDAFEKFLEKGKEIKVVIKPNPPLKIQDLFVVAAVQKDERELLKLLNPVIEVK
What are the official names of this protein?
Uncharacterized protein aq_1923.
Protein: NODD3_RHIME
Sequence: MRFKGLDLNLLVALDALMTKRSVTAAARSINLSQPAMSSAIARLRSYFQDELFRMQGRELITTPRAEALAPAIRDALLHIQFSIISWDMFNPAQSDRCFRIILSDFMTLVFFEKVVERVAREAPGVSFELLPPDDNPDELLRRGEVDFLIFPDVFMSSVHPKAKLFDQTLVSVGCLTNEQLLGDLSFERYMSMGHVAAQFGRALKPSVEQWLLLEHGYKRRIELVVPGFNLIPPLLSGTKRIAIIPLRLANHFAKSIPLRIVKHPLPLLSFTEAVQWPALHNKDQASIWMREILLDEAARIAAPRETAGCLGR
What is the function of this protein?
NodD regulates the expression of the nodABCFE genes which encode other nodulation proteins.  NodD is also a negative regulator of its own expression.  Binds flavonoids as inducers.
What are the official names of this protein?
Nodulation protein D 3.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: FTHS_DESOH
Sequence: MAYDATKMADWQISEEAEKNMPMPEEWCEKLGLEKEEMLAMGRLSKLDFLKIIKRLEAKPDGKYIEVTAITPTPLGEGKSTTSLGLMEGLGARGKSVGGALRQPSGGPTMNVKGTAAGGGNSLLIPMTEFSLGLTGDINDIMNAHNLGMVAMTARMQHERNYNDEQLQRLTGMRRLDIDPTRVEMGWIIDFCAQALRNIVIGLGGRTDGYTMQSKFGIAVGSELMAILAVATDLADLKERINNITVAFDKSGKPVTCRDLEVGNAMAAFMRNTINPTLMSTAEYQPCLVHAGPFANIAVGQSSIIADRVGLKLWDYHVTESGFAADIGFEKFWNVKCRFSGLKPHVSVLTATIRALKMHGGGPKVVAGKALDDAYTKENLALVEKGVENMVHMIGVIRKSGINPVVCVNRFYTDTDAEVAIVKKAAEAAGARCAESKHWEKGGEGALEFADAVIDACEEGNDFDFLYPLEMKLRDRVDKIAREVYGADGVDWSPEATAKAEMLENDPKYADFATMMVKTHLSLTHDPVKKGVPKGWRLPIRDVLIYSGAKFLCPCAGTISLMPGTGSNPAFRRIDVDPATGKVSGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: YF034_YEAST
Sequence: MTSSLVIYIFLWSRLICQIFPCERPGQPFAYHILGEAKKKKNRKRENRTCSIGNTCTQTYTYTPYAKKARQQEKLWERRNERTYGANSQQTFEHT
What are the official names of this protein?
Putative uncharacterized protein YFR034W-A.
Protein: PSAA_NYMAL
Sequence: MIIRSPEPEVKILVDRDPVKTSFEEWARPGHFSRTIAKGPDTTTWIWNLHADAHDFDSHTNDLEEISRKVFSAHFGQLSIIFLWLSGMYFHGARFSNYEAWLSDPTHIGPSAQVVWPIVGQEILNGDVGGGFRGIQITSGFFQIWRASGITSELQLYCTAIGALVFAALMLFAGWFHYHKAAPKLAWFQDVESMLNHHLAGLLGLGSLSWAGHQVHVSLPINQFLNAGVDPKEIPLPHEFILNRDLLAQLYPSFAEGATPFFTLNWSKYAEFLTFRGGLDPVTGGLWLTDIAHHHLAIAILFLIAGHMYKTNWGIGHDLKDILEAHKGPFTGEGHKGLYEILTTSWHAQLALNLAMLGSLTIVVAHHMYSMPPYPYLATDYGTQLSLFTHHMWIGGFLIVGAAAHAAIFMVRDYDPTTRYNDLLDRVLRHRDAIISHLNWVCIFLGFHSFGLYIHNDTMSALGRPQDMFSDTAIQLQPIFAQWIQNTHALAPSATAPGATAGTSLTWGGGDLVAVGGKVALLPIPLGTADFLVHHIHAFTIHVTVLILLKGVLFARSSRLIPDKANLGFRFPCDGPGRGGTCQVSAWDHVFLGLFWMYNAISVVIFHFSWKMQSDVWGSISDQGVVTHITGGNFAQSSITINGWLRDFLWAQSSQVIQSYGSSLSAYGLFFLGAHFVWAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPATQPRALSIIQGRAVGVTHYLLGGIATTWAFFLARIISVG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PSI-A, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: KGUA_CHRSD
Sequence: MPIQPPSKGTLYIVSAPSGAGKTSLVRALLERVAGIQVSVSHTTRAMRPGEQNGINYHFVDVATFERLIESGDFIEHARVFDNYYGTSRAAVQALLDAGQDVILEIDWQGARQVREAFDEAVSIFILPPSREALHARLAGRGTDDAATIARRMRDAVDEMSHYDEYEHVIINDTFDHALDELSCLVHAQRTRMPRVQAEHAPLLAALLSRVEDVE
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_PHEZH
Sequence: MANTPGAKKAVRKIARRTEVNTARRSRVRTFLRKFEEALASGDAGAAKAAFVQAQSELMRAVSKGVVHKNTGARKVSRLAARLKKLSAA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: COXX_PROM5
Sequence: MKSNLENFNFQTSIREQVVPSRKKVILPAWLEVAKPRLIPLLLATTLGGMALTEEWPLSSPKLICTLGGGALAAAAAGALNCLWEMDLDKRMKRTSNRALPSGKLSFNTVFLGAVSCTFAAAMLLISGVNYLAAGLTLLGLCSYVILYTIILKPRTTQNIVFGGVAGAIPPLVGASAATGHVGLSGWWLFGLVMLWTPAHFWALAILLKDDYASVGIPMLPSVKGSAFTVKAISRYGWATVFMSILGVFALPEGGLLYVIMLLPFNGRLLQLINRLKSSPDDLEKAKGLFRWSILYMFGICLLLLISRTQLSVDFEQQSMQIFLSLKAYFNI
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PLSX_RUEPO
Sequence: MTAQPDQTGSASGQIIISVDAMGGDAGPSVVVAGIAKSAKKNPQVGFILHGPEDTLKKLVAKRRVLDGRVVFRDCPDVVTMEDKPSQVVRNGKNTSMWSTLESVRNGEAAGAVSCGNTGALMALSMLRLRRLPGVTRPAIAILFPSGNPQGFNVLLDAGADIRADARDLLQYALMGASYARNGMNLLRPRVGLLNVGTEEHKGKAELKEAQALIAEYAERANYEFVGFVEGSDIPGKRCDVIVTDGFTGNVAIKTGEGTARMIGSLLREAFKYSPLSRLASLLAVTSLRRLSKRIDPRRVNGGVFLGLNGTVIKSHGSADDTGISAAVKLAFTLAQSGFAERLAARVASAAALTQDEAAPTGAQAEKQESR
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: DGLB_RAT
Sequence: MPGMVLFGRRWSLASDDLVFPGSFELFLRVLWWIASLTLYLMHRRKLDCPGGVLLSTYLIVLLVLLAVIIGIVLAIVCVSMRGTICNPGPRKSMSKLLYIRLALFLPEMVWASLGAAWVAKGIQCDRTVVIGIIATVIVSWIVIAATMVTIVFVFDPLGGKMAPYPPCIPEHLDSNSSNHLLTGLRTAAKSVWETRVQCCCCCIGQDDNTRVAFSSTADLFSTYFSDTDLVPSDIAAGFTLLHQQQDKISHSREPSEVVTHTPGQPQETELDAEVENCHHYMPFSPVCSPWPVCVLNSSRVELCRTGNNFCRGRDIEYDAVEGDEHHCHFASILKTTGLQYRDFIHVSFHDKVYELPFIVVLDHRKESVVVAVRGTMSLQDVLTDLSAESENLELDIELQDCVAHKGIAQAARYIYRRLVNDGILSQAFSVAPEYRLVVVGHSLGAGAAALLAIMLRGAYPQVRAYAFSPPRGLLSKSLFEYSKDFVVSLILGMDVIPRLSVANMEDLKRRILRVIANCNKPKYKILLHGCWYSVFGGSPDNFPTELDEGNQGALTQPLLGEQTLLTRCSPGYCSGDSPLDSPKYPTLYPPGRIIHLEEEGGSGRFGCCSAAQYRARWAHETEFSKILIGPKMLIDHMPDVMIRALDRVVADRTACVSCPGQGGSNVP
What is the function of this protein?
Lipase that catalyzes the hydrolysis of arachidonic acid (AA)-esterified diacylglycerols (DAGs) to produce the principal endocannabinoid, 2-arachidonoylglycerol (2-AG) which can be further cleaved by downstream enzymes to release arachidonic acid (AA) for cyclooxygenase (COX)-mediated eicosanoid production.  Preferentially hydrolyzes DAGs at the sn-1 position in a calcium-dependent manner and has negligible activity against other lipids including monoacylglycerols and phospholipids (By similarity).  Plays a key role in the regulation of 2-AG and AA pools utilized by COX1/2 to generate lipid mediators of macrophage and microglia inflammatory responses.  Functions also as a polyunsaturated fatty acids-specific triacylglycerol lipase in macrophages.  Plays an important role to support the metabolic and signaling demands of macrophages (By similarity).
What are the official names of this protein?
Diacylglycerol lipase-beta, DAGL-beta, DGL-beta, PUFA-specific triacylglycerol lipase, Sn1-specific diacylglycerol lipase beta.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MT21A_DANRE
Sequence: MALVPYDENVLPALSKLHQSSAEFTLANHRIRLSQDWKRLGVAAVVWDAAVVLCMFLEMGKVDLKGKRVIELGAGTGLVGIVAALLGANVTITDREPALEFLTANVHENIPQGRQKAVQVSELTWGENLDLYPQGGYDLILGADIVYLEETFPALLQTLEHLSSGDTVVLLSCRIRYERDERFLTELRQRFSVQEVHYDSQRDIHVYRAVKNKSNTEL
What is the function of this protein?
Protein-lysine methyltransferase that selectively trimethylates residues in heat shock protein 70 (HSP70) family members.
What are the official names of this protein?
Protein N-lysine methyltransferase METTL21A, Methyltransferase-like protein 21A.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL21 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_ANADE
Sequence: MSRVGKMPVKIPEKVKVSVDGNVVKVEGPKGKMHFPTNPLVSVQVDKGEVKVARQDESHVAKGLHGLTRTLVKNALEGVVKGYEKGLEINGVGFKAEVKGKEIHFTLGFSHPVVFKLPEGVTAEVDAKQTKLTIRSVDKHLLGLTAAKVRDLRPPEPYKGKGIKYADETIRRKEGKTGAA
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: GCH1_STRPS
Sequence: MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGLGQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKLARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATLTTVARGLFETDKDLRDQAYRLMGL
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: RL28_METS4
Sequence: MSRRCELTGKAVLTGHLVSHSNRKTKRRFLPNLCNVTLLSDTLGRSVRLRISANALRSVEHRGGLDAFLVKAGEQDLSQNARLLKREIEKKLAAAA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: NXT2_HUMAN
Sequence: MATSLDFKTYVDQACRAAEEFVNIYYETMDKRRRALTRLYLDKATLIWNGNAVSGLDALNNFFDTLPSSEFQVNMLDCQPVHEQATQSQTTVLVVTSGTVKFDGNKQHFFNQNFLLTAQSTPNNTVWKIASDCFRFQDWSSS
What is the function of this protein?
Regulator of protein export for NES-containing proteins.  Also plays a role in mRNA nuclear export.
What are the official names of this protein?
NTF2-related export protein 2, Protein p15-2.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm.
Protein: RL17_ECOLU
Sequence: MRHRKSGRQLNRNSSHRQAMFRNMAGSLVRHEIIKTTLPKAKELRRVVEPLITLAKTDSVANRRLAFARTRDNEIVAKLFNELGPRFASRAGGYTRILKCGFRAGDNAPMAYIELVDRSEKAEAAAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: LPXB_BURO1
Sequence: MPLPTNQLRLAMVAGEPSGDLLAASLLGGLRERLPESAQYYGIGGQRMIAQGFDSHWQMDKLTVRGYVEALGQIPEILRIRGELKRQLLAERPAAFIGVDAPDFNFNVEQAARDAGIPSIHFVCPSIWAWRGGRIKKIAKSVDHMLCLFPFEPAILDKAGVASTYVGHPLADDIPLEPDTHGARIALGLPADGPVIAVLPGSRRSEIALIGPTFFAAMALMQQREPGVRFVMPAATPALRELLQPLVDAHPQLALTITDGRSQVAMTAADAILVKSGTVTLEAALLKKPMVISYKVPWLTGQIMRRQGYLPYVGLPNILAGRFVVPELLQHFATPEALADATLTQLSDDANRRTLTEVFTEMHLSLRQNTAAKAAEAVVRVLEQRKGRA
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: YOEB_SHIFL
Sequence: MKLIWSEESWDDYLYWQETDKRIVKKINELIKDTRRTPFEGKGKPEPLKHNLSGFWSRRITEEHRLVYAVTDDSLLIAACRYHY
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  It has been proposed to be an mRNA interferase but also an inhibitor of translation initiation.  Has an in vitro RNase activity and preferentially cleaves at the 3'-end of purine ribonucleotides.  YefM binds to the promoter region of the yefM-yeoB operon to repress transcription, YeoB acts as a corepressor (By similarity).
What are the official names of this protein?
Toxin YoeB, Putative endoribonuclease YoeB, Putative mRNA interferase Yoeb, Toxin RelE2.
What is the protein family that this protein belongs to?
Belongs to the YoeB family.
Protein: BIOD_PSEA7
Sequence: MPAFFVTGTDTEIGKTTIAAGLLHAARSAGLSTAAAKPVASGCEATAQGLRNGDALALLGECSLALAYEQVNPLAFEPAIAPHLAAREAGVELSAARLHDAVREVLALRADFTLVEGAGGWRVPLQGRENLSDLARLLGLPVVLVVGVRLGCINHALLSAEAILGDGLALAGWVANIVDPATSRLEENLATLAERLPAPCLGRVPRLADAGPAAVAAHLDLRPLGIGL
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_MYCSK
Sequence: MAAKKAGKAGATKDRNNQVVASNRRARHNYAILDTYEAGIALMGTEVKSLRDGQASLADAFATVDDGEIWLRNLHIPEYQHGSWTNHAPRRNRKLLLHRREIDNLIGKIRDGNLTLVPLSLYFTGGKVKVELALARGKQAHDKRQDLARRDAEREVVRELGRRAKGMS
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: MAK16_XENTR
Sequence: MQHDDVIWDVVGNKQFCSFKIKTKTQNFCRNEYNITGLCNRSACPLANSQYATIKEEKGICYLYMKTIERAAFPARMWERVRLSKNYEQALEQIDESLIYWPRFIRHKCKQRFTKITQYLIRIRKLTLKRQRKLVPLSRKVERREKRREEKALVAAQLDNAIEKELLERLKQGAYGDIYNFPIQAFDKALEQQEDASASESSEEEEEEDDEESGKREFVEDEDVDESDLSDFEDMDKLGASSEEEKSSGEEESSEEEEEKAPKAKSKGKAPVKGQLIRKRQHVEIEYEQETEPQHKAKVT
What are the official names of this protein?
Protein MAK16 homolog, MAK16-like protein.
What is the protein family that this protein belongs to?
Belongs to the MAK16 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: Y2291_ARCFU
Sequence: MDTRLIAIATFVVTFGILIVLKRLNYIESWDTFSILSILAAVLTIAAYFFTLVLFPQDYDQLKKEILDEINESLKNYEIYFKCKDFKKPIVKDGAVRIDKCVVMATKLNLTDHGYIVDLKFRSNWMDSKGTHAILFIDGDDAQINLFEREGEIFYIIKSKNKISGVYIQLKSVKWFDEAFSDNWNNIKIMWDTSKDEIWLEINGIRVSKKLNFDFNLNDSVIYLGSNPLEDTYAEGYFDRIMVYKSADTADFGTPTVRRFE
What are the official names of this protein?
Uncharacterized protein AF_2291.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KAD_AYWBP
Sequence: MILILLGPPGIGKGTQASVLSYILKINHISTGDIFRKNFKENTELGTLSKKFIAQGLLVPDDITNQMIADYLSKDIATKDFLLDGFPRNVLQARFLDDFFKKSHLFLTKVIYFNAGTKDLMKRIAGRRICPECGKVYHIEKIPPKNPGICDKDQKTLIQREDDKPETFLKRLKVFNKETLPLVQYYCEQNQLFEVDGMQTIDQVTKMILEVLETDRK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_RICCN
Sequence: MSILHATILTVFPEMFPGTLGHSLAGQALNKNIWSYDVINIRDFGLTKHKNIDDEAYGGGNGLIMRPDVLGSSIDHALALNPNAEMYYPSPRGRVFTQSFAKEMLKNKNLIFLCGRYEGIDERVIEEYNVKEISVGDYILSGGEIPTLTILDCLIRLLPGVLMNQNTLSSESFEEDGEFKGGLECSLYTRPEIWRGRAVPSVLLSGNHRLINEWKKEQSHMITKLRRPELLKDL
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMAP_BOVIN
Sequence: MSAARESHPHGVKRSASPDDDLGSSNWEAADLGNEERKQKFLRLMGAGKKEHTGRLVIGDHKSTSHFRTGEEDKKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVDDHDGEGDVAGDDDDDDSPDPESPDDSESDSESEKEESTEELQAAEHPDEVEDSKNKKDAKSNYKMMFVKSSGS
What are the official names of this protein?
Small acidic protein.
What is the protein family that this protein belongs to?
Belongs to the SMAP family.
Protein: RL13E_SULIL
Sequence: MEFPKALIKRPNYHFEYPHKRKDKRIGRGFSIGELEKAGLNINNARKLGIIVDIRRKSVHEENVEVLKKFLEQLPNQKS
What are the official names of this protein?
50S ribosomal protein L13e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL13 family.
Protein: HIS7_SALRD
Sequence: MSTPSFSPRTATVERTTAETDVSVALTLDGDGSYDVDTGVGFFDHMLSLFAKHGALDLEVRCDGDLEVDDHHTVEDVAIGLGRALDDALGDKAHIARYGHAYVPMDDALARAVVDLSGRSYCHLEASFERNQVGGLSTELVEHVWRSVADHARCNLHLTVLRGHNAHHKIEALFKAAARALRTAVRRRADHAEVASTKGTLA
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1998_SYMTH
Sequence: MPGTSDKTVYWRNKPEDRNPGEVLQKVYAALKEKGYSPIDQIVGYLLSGDPTYITSHMGARNLIRRIERDELLEELVRSYLEKLEE
What are the official names of this protein?
UPF0297 protein STH1998.
What is the protein family that this protein belongs to?
Belongs to the UPF0297 family.
Protein: HIS7_BACCZ
Sequence: MREFSQIRETTETKIKLSLQLDEGKNVSVQTGVGFFDHMLTLFARHGRFGLQVEAEGDVFVDAHHTVEDVGIVLGNCLKEALQNKEGINRYGSAYVPMDESLGFVAIDISGRSYIVFQGELTNPKLGDFDTELTEEFFRAVAHAANITLHARILYGSNTHHKIEALFKAFGRALREAVERNAHITGVNSTKGML
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STAT1_CAEEL
Sequence: MMGSSSQELQTALTDVSKTCHHLWEENKDLQGRFVNELGELQRLQMVIAQLEQQQRLENVFTVKQQMTELQKRAATLYEHLTQKRNDIVIKLNDGTNFATMLQTQLIGEKLFSWKNAQKLAQIGMPFDNREQLLDEIQIEFEFLADQNWQLNMFSCWMLDLLRRAPQLNDGLAQATIGKLTAITEQLNKLLFMLVSQSFIVSVQPEPVLKTQHKFVTEVRLLIGDKLGIRQHLVNTNVSVKIIAEDEAKQLSVDYDAHKEIRNNKTVGTISNDFEKLTMNERGHLAAKFNNSKLTRIAHRKPPPKGASDLKCAASMQAATDQKYALLFFITPFQMGNLSKEEQFDVWTLSLPIMVTVHGSQDCDAQVAILWHRAFASISRNPNTTDVTAVTWDNLAIMLRNKFSLFTGARRPLSDSDLAYLSEKMLMPNVADQKPITFHRFAKQAMRDDLPFSFWEWFFSIMQLIKQKLLKFWDEGWCIGFISKNDASQSMMMCQHSSFLLRFSDSQTGAVSIGFVCEEADGQKIPFHLAPFTIKDLDQLSLASRIASCPQLKDIRYMYPAIDKEEMLRFFESEERHRVGGGDSPTGYIQSEIVMVAKTNGNFRRMSNAPSMFGADSPSPLSVQSKLDWSPGEVHQNHMMEMSDELGQILTVSDMSGDVETLLGPAFKNNITNYNPHDGNHQHNLHFVDMSQQGMMQQHHNQFYPS
What is the function of this protein?
Carries out a dual function: signal transduction and activation of transcription.  Activated STAT proteins play a role in repression of dauer formation.  Neuronal expression is held in check by negative signals through the TGF-beta pathway that target the daf-3 transcription factor.
What are the official names of this protein?
Signal transducer and activator of transcription 1.
What is the protein family that this protein belongs to?
Belongs to the transcription factor STAT family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocated into the nucleus in response to phosphorylation.