PharMolix/UniProtQA huggingface dataset:
Protein: FNBA_STAAW
Sequence: MKNNLRYGIRKHKLGAASVFLGTMIVVGMGQDKEAAASEQKTTTVEENGNSATENKVNETQTTTTNVNTIDETQSYSATATEQPSNATQVTTEEAPKAVQAPQTAQPANLETVKEEVVKEEAKPQVKETTQSQDNSGDQRQVDLTPKKATQNQVAETQVEVAQPRTASESKPRVTRSADVVEAKEASDEKVETGTDVTSKVTVESGSIEAPQGNKVEPHAGQRVVLKYKLKFADGLKRGDYFDFTLSNNVNTYGVSTARKVPEIKNGSVVMATGEILGNGNIRYTFTNEIEHKVEVTANLEINLFIDPKTVQSNGEQKITSKLNGEETEKTIPVVYNPGVSNSYTNVNGSIETFNKESNKFTHIAYIKPMNGNQSNTVSVTGTLTEGSNLAGGQPTVKVYEYLGKKDELPQSVYANTSDTNKFKDVTKEMNGKLSVQDNGSYSLNLDKLDKTYVIHYTGEYLQGSDQVNFRTELYGYPERAYKSYYVYGGYRLTWDNGLVLYSNKADGNGKNGQIIQNNDFEYKEDTAKGTMSGQYDAKQIIETEENQDNTPLDIDYHTAIDGEGGYVDGYIETIEETDSSAIDIDYHTAVDSEAGHVGGYTESSEESNPIDFEESTHENSKHHADVVEYEEDTNPGGGQVTTESNLVEFDEESTKGIVTGAVSDHTTIEDTKEYTTESNLIELVDELPEEHGQAQGPIEEITENNHHISHSGLGTENGHGNYGVIEEIEENSHVDIKSELGYEGGQNSGNQSFEEDTEEDKPKYEQGGNIVDIDFDSVPQIQGQNNGNQSFEEDTEKDKPKYEQGGNIIDIDFDSVPQIHGFNKHTEIIEEDTNKDKPNYQFGGHNSVDFEEDTLPKVSGQNEGQQTIEEDTTPPTPPTPEVPSEPETPTPPTPEVPSEPETPTPPTPEVPSEPETPTPPTPEVPAEPGKPVPPAKEEPKKPSKPVEQGKVVTPVIEINEKVKAVAPTKKAQSKKSELPETGGEESTNKGMLFGGLFSILGLALLRRNKKNNKA
What is the function of this protein?
Promotes bacterial attachment to multiple substrates, such as fibronectin (Fn), fibrinogen (Fg), elastin peptides and tropoelastin.  This confers to S. aureus the ability to invade endothelial cells.  Promotes adherence to and aggregation of activated platelets (By similarity).
What are the official names of this protein?
Fibronectin-binding protein A.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor. Note=Anchored to the cell wall by sortase A (By similarity).
Protein: FUMC_MYCTO
Sequence: MAVDADSANYRIEHDTMGEVRVPAKALWRAQTQRAVENFPISGRGLERTQIRALGLLKGACAQVNSDLGLLAPEKADAIIAAAAEIADGQHDDQFPIDVFQTGSGTSSNMNTNEVIASIAAKGGVTLHPNDDVNMSQSSNDTFPTATHIAATEAAVAHLIPALQQLHDALAAKALDWHTVVKSGRTHLMDAVPVTLGQEFSGYARQIEAGIERVRACLPRLGELAIGGTAVGTGLNAPDDFGVRVVAVLVAQTGLSELRTAANSFEAQAARDGLVEASGALRTIAVSLTKIANDIRWMGSGPLTGLAEIQLPDLQPGSSIMPGKVNPVLPEAVTQVAAQVIGNDAAIAWGGANGAFELNVYIPMMARNILESFKLLTNVSRLFAQRCIAGLTANVEHLRRLAESSPSIVTPLNSAIGYEEAAAVAKQALKERKTIRQTVIDRGLIGDRLSIEDLDRRLDVLAMAKAEQLDSDRL
What is the function of this protein?
Involved in the TCA cycle.  Catalyzes the stereospecific interconversion of fumarate to L-malate.
What are the official names of this protein?
Fumarate hydratase class II, Fumarase C, Aerobic fumarase, Iron-independent fumarase.
What is the protein family that this protein belongs to?
Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOL1_ARATH
Sequence: MSKLRFFQSLLISTVICFFLPSINARGGHSDHIHPGDGNYSFHGIVRHLFAQEEPTPSLELTRGYMTNDDLEKAMKDFTKRCSKISRLYSIGKSVNGFPLWVIEISDRPGEIEAEPAFKYIGNVHGDEPVGRELLLRLANWICDNYKKDPLAQMIVENVHLHIMPSLNPDGFSIRKRNNANNVDLNRDFPDQFFPFNDDLNLRQPETKAIMTWLRDIRFTASATLHGGALVANFPWDGTEDKRKYYYACPDDETFRFLARIYSKSHRNMSLSKEFEEGITNGASWYPIYGGMQDWNYIYGGCFELTLEISDNKWPKASELSTIWDYNRKSMLNLVASLVKTGVHGRIFSLDKGKPLPGLVVVKGINYTVKAHQTYADYHRLLVPGQKYEVTASSPGYKSKTTTVWLGENAVTADFILIPETSSRGNQLRSSCDCSCKSCGQPLLTQFFTETNNGITLTLFVVVVFLCFLLQRRVRFNLWKQRQSSRRSITV
What is the function of this protein?
Possesses in vitro carboxypeptidase activity against the C-terminal arginine and lysine residues.  Involved in the maturation of CLE19.  Removes the C-terminal arginine residue of CLE19 proprotein.  The cleavage of the C-terminal arginine residue is necessary for CLE19 activity in vivo.  Is not involved in generating active CLV3 (PubMed:24118638).  Is not involved in CLE19 or CLV3 perception (PubMed:12932329, PubMed:24118638).
What are the official names of this protein?
Carboxypeptidase SOL1, Protein SUPPRESSOR OF LLP1 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Endosome membrane; Single-pass type I membrane protein.
Protein: TPP2_DROME
Sequence: MFNRFRLVHKQLRLYKNFGLLGQKASVGLTLPIISLSRPYMAYMGTERSVVMITAPATKEFAESSERSNSSKKTTNKEQSDKSAESRMATSGIVESFPTGALVPKAETGVLNFLQKYPEYDGRDVTIAIFDSGVDPRATGLETLCDGKTVKVIERYDCSGCGDVDMKKKVTPDENGNIKGLSGNSLKLSPELMALNTDPEKAVRVGLKSFSDLLPSKVRNNIVAQAKLKHWDKPHKTATANASRKIVEFESQNPGEASKLPWDKKILKENLDFELEMLNSYEKVYGDIKTSYDCILFPTADGWLTIVDTTEQGDLDQALRIGEYSRTHETRNVDDFLSISVNVHDEGNVLEVVGMSSPHGTHVSSIASGNHSSRDVDGVAPNAKIVSMTIGDGRLGSMETGTALVRAMTKVMELCRDGRRIDVINMSYGEHANWSNSGRIGELMNEVVNKYGVVWVASAGNHGPALCTVGTPPDISQPSLIGVGAYVSPQMMEAEYAMREKLPGNVYTWTSRDPCIDGGQGVTVCAPGGAIASVPQFTMSKSQLMNGTSMAAPHVAGAVALLISGLKQQNIEYSPYSIKRAISVTATKLGYVDPFAQGHGLLNVEKAFEHLTEHRQSKDNMLRFSVRVGNNADKGIHLRQGVQRNSIDYNVYIEPIFYNDKEADPKDKFNFNVRLNLIASQPWVQCGAFLDLSYGTRSIAVRVDPTGLQPGVHSAVIRAYDTDCVQKGSLFEIPVTVVQPHVLESDQNTPVFEPASSKGDNSVEFQPNTIQRDFILVPERATWAELRMRITDPNRGEDIGKFFVHTNQLLPKQSCRKLETMKIVSVGSENESIMAFKVKSGRILELCIAKYWSNYGQSHLKYSLRFRGVEAHNPNAYVMHAGRGIHKLEIEALVAEDVQPQLQLKNAEVVLKPTEAKISPLSATRDVIPDGRQVYQNLLAFNLNVAKAADVSIYAPIFNDLLYEAEFESQMWMLFDANKALVATGDAHSHTSFTKLDKGEYTIRLQVRHEKRDLLEKISEANLVASFKLTSPLTLDFYENYNQCIVGGRKYVSSPLRLSTRVLYIAPITQERLTKANLPAQCAWLSGNLVFPQDEVGRRVAQHPFTYILNPAEKKSHTNGSSNGSSAAGSTATAAAVTTANGAKPKAPATPQAATSVTNPAAGDGISVQNDPPVDSSGSPASPKKGKANADDYAESFRDFQCSQIVKCELEMAEKIYNDVVAAHPKHLQANLLLIQNIESNQLKSQLPLTFVNAQKTSPPEAGESADKQKEDQKKVRSALERIVKLADKVIQETDSEALLSYYGLKNDTRADAAKIKTNMDKQKNTLIEALSKKGIAVAKLAVLDDCIKDSLAEINELYTEIIKFVDANDSKAIQFALWHAYAHGHYGRMYKYVVKLIEEKRTRDHFVELAAINGALGHEHIRTVINRMMITAFPSSFRLF
What is the function of this protein?
Component of the proteolytic cascade acting downstream of the 26S proteasome in the ubiquitin-proteasome pathway (By similarity).  Efficiently cleaves Ala-Ala-Ala-polypeptide and Pro-Pro-Ala-polypeptide, Val-Leu-Lys-polypeptide only at high concentration.  Does not cleave Ala-Phe-Pro-polypeptide nor Pro-Leu-Gly-polypeptide.
What are the official names of this protein?
Tripeptidyl-peptidase 2, TPP-2, Tripeptidyl aminopeptidase, Tripeptidyl-peptidase II, TPP-II, dTPP II.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FKBP_NEIMC
Sequence: MGSLIIEDLQESFGKEAVKGKEITVHYTGWLEDGTKFDSSLDRRQPLTITLGVGQVIKGWDEGFGGMKEGGKRKLTIPSEMGYGAHGAGGVIPPHATLIFEVELLKVYE
What is the function of this protein?
PPIases accelerate the folding of proteins.
What are the official names of this protein?
FK506-binding protein, Peptidyl-prolyl cis-trans isomerase, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family.
Protein: RS9_NITWN
Sequence: MADTIQSLDQLSALKPAESEAPKHTKKVDKYGRAYATGKRKDAVARVWIKPGAGKILVNAREVDVYFARPVLRMMIQQPLVAAARAGQYDVVCTVAGGGLSGQAGAVRHGLSKALTHFEPELRGVLKKGGFLTRDSRVVERKKYGKAKARRSFQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: NU2C1_GOSHI
Sequence: MIWHVQNENFILDSTRIFMKAFHLLLFDGSFIFPECILIFGLILLLMIDSTSDQKDIPWLYFISSTSLVMSITALLFRWREEPMISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAIAEFLLFVLTATLGGMFLCGANDLITIFVAPECFSLCSYLLSGYTKKDVRSNEATTKYLLMGGASSSILVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGIGFKLSPAPSHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNGGYASMITYMLFYISMNLGTFACIVLFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGLPPLAGFFGKLHLFWCGWQAGLYFLVSIGLLTSVVSIYYYLKIIKLLMTGRNQEITPHVRNYRRSPLRSNNSIELSMIVCVIASTIPGISMNPIIAIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 A, chloroplastic, NAD(P)H dehydrogenase, subunit 2 A, NADH-plastoquinone oxidoreductase subunit 2 A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: THII_YERPA
Sequence: MKFIIKLFPEITIKSQSVRLRFIKILTTNIRNVLKHLEDDTLAIVRHWDHIELRTKDDNLGPEICDALTRIPGIHHILEVEDRSYSDMHNIFEQTLEAYRETLVGKTFCVRVKRRGKHEFSSGDVERYVGGGLNQHIESAKVNLTRPQVTVNLEVDQDKLILVKARHEGLGGFPIGTQEDVLSLISGGFDSGVSSYMLMRRGCRVHYCFFNLGGSAHEIGVKQVAHYLWNRFGSSHRVRFIAIDFEPVVGEILEKVEDGQMGVVLKRMMVRAASQVAERYGVQALVTGEALGQVSSQTLTNLRLIDNASDTLILRPLISHDKEHIINLARQIGTEDFAKTMPEYCGVISKSPTVKAVKAKIEEEESHFDFSILDRVVSEAKNVDIREIAQQSREQVVEVETVAELADTDVLLDIRAPDEQEEKPLKLDQVEVRSLPFYKLSSQFADLDQSKTYLLYCDRGVMSRLQALYLREQGYTNVKVYRP
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOR_ECO57
Sequence: METRREERIGQLLQELKRSDKLHLKDAAALLGVSEMTIRRDLNNHSAPVVLLGGYIVLEPRSASHYLLSDQKSRLVEEKRRAAKLAATLVEPDQTLFFDCGTTTPWIIEAIDNEIPFTAVCYSLNTFLALKEKPHCRAFLCGGEFHASNAIFKPIDFQQTLNNFCPDIAFYSAAGVHVSKGATCFNLEELPVKHWAMSMAQKHVLVVDHSKFGKVRPARMGDLKRFDIVVSDCCPEDEYVKYAQTQRIKLMY
What is the function of this protein?
This protein is one of the repressors that regulate the expression of deoCABD genes, which encode nucleotide and deoxy ribonucleotide catabolizing enzymes.  It also negatively regulates the expression of nupG (a transport protein) and tsx (a pore-forming protein).  The inducer is deoxyribose-5-phosphate (By similarity).
What are the official names of this protein?
Deoxyribose operon repressor.
Protein: HEPA_VZVO
Sequence: MDATQITLVRESGHICAASIYTSWTQSGQLTQNGLSVLYYLLCKNSCGKYVPKFAEITVQQEDLCRYSRHGGSVSAATFASICRAASSAALDAWPLEPLGNADTWRCLHGTALATLRRVLGFKSFYSPVTFETDTNTGLLLKTIPDEHALNNDNTPSTGVLRANFPVAIDVSAVSACNAHTQGTSLAYARLTALKSNGDTQQQTPLDVEVITPKAYIRRKYKSTFSPPIEREGQTSDLFNLEERRLVLSGNRAIVVRVLLPCYFDCLTTDSTVTSSLSILATYRLWYAAAFGKPGVVRPIFAYLGPELNPKGEDRDYFCTVGFPGWTTLRTQTPAVESIRTATEMYMETDGLWPVTGIQAFHYLAPWGQHPPLPPRVQDLIGQIPQDTGHADATVNWDAGRISTVFKQPVQLQDRWMAKFDFSAFFPTIYCAMFPMHFRLGKIVLARMRRGMGCLKPALVSFFGGLRHILPSIYKAIIFIANEISLCVEQTALEQGFAICTYIKDGFWGIFTDLHTRNVCSDQARCSALNLAAACERAVTGLLRIQLGLNFTPAMEPVLRVEGVYTHAFTWCTTGSWLWNLQTNTPPDLVGVPWRSQAARDLKERLSGLLCTATKIRERIQENCIWDRVLYDIWAGQVVEAARKTYVDFFEHVFDRRYTPVYWSLQEQNSETKAIPASYLTYGHMQDKDYKPRQIIMVRNPNPHGPPTVVYWELLPSCACIPPIDCAAHLKPLIHTFVTIINHLLDAHNDFSSPSLKFTDDPLASYNFLFL
What is the function of this protein?
Component of the helicase/primase complex.  Unwinds the DNA at the replication forks and generates single-stranded DNA for both leading and lagging strand synthesis.  The primase synthesizes short RNA primers on the lagging strand that the polymerase presumably elongates using dNTPs.  The primase-associated factor has no known catalytic activity in the complex and may serve to facilitate the formation of the replisome by directly interacting with the origin-binding protein and the polymerase.
What are the official names of this protein?
DNA helicase/primase complex-associated protein, HEPA, Primase-associated factor.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae HEPA family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: KAD_SALHS
Sequence: MRIILLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVKSGSELGKQAKDIMDAGKLVTDELVIALVKERIAQEDCRNGFLLDGFPRTIPQADAMKEAGIVVDYVLEFDVPDELIVDRIVGRRVHAASGRVYHVKFNPPKVEGKDDVTGEDLTTRKDDQEETVRKRLVEYHQMTAPLIGYYQKEAEAGNTKYAKVDGTQAVADVRAALEKILG
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_BURPS
Sequence: MENTQENPTDQTTEETGREAQAAEPAAQAAENAAPAAEAALAEAQAKIAELQESFLRAKAETENVRRRAQDDVAKAHKFAIEGFAENLLPVLDSLEAAVGDTSGDLAKVREGVELTLRQLTSALEKGRVAALNPVGEKFDPHLHQAISMVPADQEPNTVVAVLQKGYTIADRVLRPALVTVAQPK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUC_LYSSC
Sequence: MGKNIIEKIWDKHVVYQEEGKPDLLYIDLHLIHEVTSPQAFEGLRMNGRQVRRPDLSFATMDHNVPTKNLPTIHDPIARNQIETLAKNAEEFGVELAGMGHPDQGIVHVIGPELGLTQPGKTIVCGDSHTSTHGAFGAIAFGIGTSEVEHVLSTQTLWQNKPKTMEIRVEGELSVGVAAKDIILAIIAKFGIGVGTGYIVEFTGEAIHKLSMEERMTICNMSIEAGAKAGLISPDQITVDYIRGRKYAPQGEQFEEAANYWLSLASDEDATYDTVRIIHAEEIEPIITWGTNPSMGTGVSGHVPTLADYKDESDKAALQKALDYMGLEEGQPLTSIDIQHVFIGSCTNSRMSDLRAAANVIKGRKVHGDVTAIVVPGSYSTKKQAEAEGLDKIFIDAGFEWRESGCSMCLAMNDDVVPAGERCASTSNRNFEGRQGAGSRTHLVSPPMAAAAAIAGHFVDVREFVKETV
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: Y1059_ARCFU
Sequence: MEKVILEHLQRIEKQLEILNSKIENFLGFEELSEEELKELDEIEAKMEKGEKFVLNDV
What are the official names of this protein?
Uncharacterized protein AF_1059.
Protein: NUDL_ENT38
Sequence: METHDLTLDDFLSRFQLLRPKMSRDVLNRRQAAVLIPLVRREQPGLLLTKRASHMRKHPGQVAFPGGAVDSTDASLIAAALREAHEEVAIPPEVVEIIGVLPPVDSVTGFQVTPVVGIIPPDLHYHASEEEVAAVFEMPLSEALRLSRYHPLDIQRRGHDHRVWLSWYQHYFVWGMTAGIIRELALQIGMKP
What is the function of this protein?
Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.
What are the official names of this protein?
Uncharacterized Nudix hydrolase NudL.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. PCD1 subfamily.
Protein: Y097_ARCFU
Sequence: MASYVFIRVSKIRKGYFPVLLAIGFAITFAEGFILFLVNFGAIPTNGPTIQLVPQIIMQNPNPLIRFYGTLILLCFLNTIVLSIFYATIAKLLPKFSG
What are the official names of this protein?
Uncharacterized protein AF_0097.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GAG_IPHA
Sequence: MGSSQSVVTALQTVLKQRDLKIAPRTLQNFMKEVDRVAPWYACSGSLTVASWNKLGKELDRKHAEGDLCLGTKAIWKLVKNCLEDEACHPAIIESQGTLEEVQDSMSETERSERMGARKRKDMSKKKGPPQEVKKGGEKEGSYHSPLNKSKKKKKPESSQYPAVELEALELDNSDSDTLDSSEEGGLEEEVARYEEKRYHPDRHRPLKTKMNVRPPPINPAGSRPSAPPPYELRLNTGTDSFLPLEERRKIQMAFPVFENAEGGRVHTPVDYNQIKELAESVRNYGVNANFTTLQVERLANFAMTPTDWQTTVKAVLPNMGQYMEWKALWYDAAQAQARVNATAGRSSGHLTKIVQGPQEPFSDFVARMTEAASRIFGDSEQAMPLIEQLVYEQATQECRAAIAPRKSKGLQDWLRVCRELGGPLTNAGLAAAILQTHRYRDLSNRKACFNCGRMGHLKKDCQAPERTRESKLCYRCGKGYHRASECGIMDSGADKSIISLHWWPKSWPTVVSSHSLQGLGYQSSPAISASALTWRDAEGKQGCFTPYVLPLPVNLWGRDVLQAMGMTLTNE
What is the function of this protein?
The aspartyl protease mediates proteolytic cleavages of Gag and Gag-Pol polyproteins during or shortly after the release of the virion from the plasma membrane.  Cleavages take place as an ordered, step-wise cascade to yield mature proteins.  This process is called maturation.  Displays maximal activity during the budding process just prior to particle release from the cell.
What are the official names of this protein?
Intracisternal A-particle Gag-related polyprotein.
Protein: MURD_ALKOO
Sequence: MNLKEKNVLVIGFAVTGIPLVKVLCQLGANVIVNDSKKEEALKESMKLLSDHPIQYILGKHPEIEELSAPLDLVVVSPGVPLDIPFIENLRARGIEIIGEIELAYRLAQGHIVAITGTNGKTTTTSLVGEIFKNAGRRTHVVGNIGVAFISKALETTADDVIVIEASSFQLESIVDFRPQVGAILNLTPDHLNRHKTMENYQKAKFNIFKNQGAEDIAVINYDDVKLREESKQIYAKKVYFSRRTLLEEGVFVEDGKIVALKDGHKKEIISKDDIFIPGNHNLENALAATAMTLSLGVDIDVIQHTLKTFKGVEHRTEIVDVIHGVRFINDSKGTNPDASIKGIEGINTPILLIAGGYDKGSDFDEFINAFDGKVKHMFVYGETANTLMETAKKLNFIDVTKVQNLDEAVKKAYDIAIQGDTVLLSPACASWDMYENFEMRGKHFKEIVANLRR
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATE_NATPD
Sequence: MSLDTVVEDIRDEARARADEIRSEGEERAEEIIDEAEREADDIVDEAEREAERKISQERDQKLSSAKLEAKQARLEARREVLEEVHDDVEAQIADIDGDEREALTRSLLDAAAEEFDGDSVRVHGHEDDADLLEGIVADYDGFEVGEPVDCLGGVVVESDASRVRVNNTFDSILEDVWEENLREISARLFEE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: Y14E_BPLZ5
Sequence: MAKVDIDIVDFEYIEEIIRNRYPELSITSVQDSKFWSIQIVIEGPLEDLTRFMANEYCDGMDSEDAEFYMGLIEQ
What are the official names of this protein?
Uncharacterized 8.8 kDa protein in frd-Gp32 intergenic region.
Protein: LGT_ACAM1
Sequence: MLPLYWAVFTSPGPEIFRVGSVVIRWYGVLIAAAIVLGLQLSRHLATYRRIKPDDISDLAIWLVIGAIPCARLYYVLFQWEYYSQHLDQVATIWRGGIAIHGAILGGMLAALIFSRLKKVSFWQLADLVAPSLILGQAIGRWGNFFNSEAFGDPTDLPWKLFIPPARRPLAYRNSAYFHPTFLYESVWNLMVLGILLALFFKFPKAKKGTIFLVYAVTYSLGRLWIEGLRTDSLMLGPLRIAQVVSLIGIGIGMLGLTWLYLLKRSLPDTKQAS
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GRH1_YEAST
Sequence: MFRIAKNLVRTFEQSVQDTLALSQDSSNLDAFFQSIPPNLLSAQLESPVDAVSEGVKHTNVNETLSGLRIVWVDEMQFQLQSFFDYIVGFNDDPVPVVSNQHGFSYPDYRRITSIFNEHCGRTLKVNIWSAKGGTFRDEYISIISKESDDLDDVSLNHDERRPSSGEAHQFQALGFKVQWTPLIASTFTYHILNVNIPDGPAQSAGLIPDEDYIIGCQDGLLATGGETLLQDIVRSRANYDLVLYVYNKVSDCVRPITVHIGPDGRLGCNVGYGFLHRIPTVKHCPQQAQQQGQDDNPVPVPVPVESETAFVPSAFTAPPVPTKKKSKNKKGTQPLAMDDYFNEGRDKSSTAAKSAESDILAPPPQKQSSSD
What is the function of this protein?
Involved in the spindle assembly checkpoint.  Involved in ER to Golgi vesicle-mediated transport by either facilitating USO1-dependent and -independent tethering or increasing target accuracy of fusion events of COPII-coated vesicles.
What are the official names of this protein?
GRASP65 homolog protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus, cis-Golgi network membrane; Peripheral membrane protein. Note=Localizes to cytoplasm in a punctate pattern. Association with the cis-Golgi requires N-terminal acetylation and is probably mediated via an N-terminal amphipathic helix. The localization to the Golgi is MAK3-dependent and SYS1- independent. Localizes to the Golgi together with BUG1.
Protein: PRP2B_ORYSJ
Sequence: MQMIGGEMWTAAGRRLHQQRDLHAILRTAHRRCCTRPIGGGLDAPAAPPGDLRTLSGVGMLIHQFKALLAPKKIYPWRSSHLQSLEVRRLHTAPSNAAAAAAVTDGGDQDKTKSAKDDDGDDKVQCKKEKIVTATKKGAAVLDQYIPDNIKTAYHVLQVGDEIYDATMNQTNVGGNNNKFYIIQALESDAGGNFMVYSRWGRVGTRDIHWSYRKGSHCYAHKYTWLEMDYGEADKETNKKTSSITNQLEETKLETRTASFISLICDISMMKQQMVEIGYNADKLPLGKLSKSTILKGYDVLKRISNVISGADTDRTQLEQLTGEFYSVIPHDFGFKKMSEFIIDTPQKLKAKLEMVEALSEIEIAIKLLEDDSSDQDHPLYARYKQFCCDFTPLEVDSEEYSMIKTYLTNTHGKTHTGYTVDIVQIFKVSRLGEMERFQKFASAGNRMLLWHGSRLTNWAGILSQGLRIAPPEAPISGFMFGKGVYFADMFSKSANYCCASEACKSGVMLLCEVALGEMNELLYGDFGADNLPNGKLSTKGVGQTEPNIAESKITDDGMVIPLGKPEKVPSRRGSLMYNEYIVYNVDQIRMRYILNVNFNFKRWG
What is the function of this protein?
Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism.  This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks (By similarity).
What are the official names of this protein?
Poly [ADP-ribose] polymerase 2-B, PARP-2-B, NAD(+) ADP-ribosyltransferase 2-B, ADPRT-2-B, Poly[ADP-ribose] synthase 2-B, Protein ADP-ribosyltransferase PARP2.
What is the protein family that this protein belongs to?
Belongs to the ARTD/PARP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NA1A_ANTXA
Sequence: GVSCLCDSDGPSVRGNTLSGTLWLYPSGCPSGWHNCKAHGPTIGWCCKQ
What is the function of this protein?
Binds specifically to voltage-gated sodium channels (Nav) (site 3), thereby delaying their inactivation.  This toxin retains the greatest capacity to discriminate between the cardiac (Nav1. 5/SCN5A) and neuronal sodium channels (2. 5 nM versus 120 nM, when electrophysiologically tested and 14 nM versus 400 nM, when tested by ion flux), whereas its paralog Anthopleurin-B has the highest affinity of all anemone toxins for the mammalian sodium channel (PubMed:13806, PubMed:7612595, PubMed:17092528).  Its ability to differentiate between cardiac and skeletal channels appears to be associated with domain 4 of the channel (PubMed:9306007).  This toxin does not slow or inhibit closed-state inactivation of cardiac sodium channels, but selectively modifies inactivation from the open-state (PubMed:8576699).  It does not display phospholipid-binding activities, suggesting that the domain IV S3-S4 linker is located at the extracellular surface and not buried in the phospholipid bilayer (By similarity).
What are the official names of this protein?
Delta-actitoxin-Axm1a, Delta-AITX-Axm1a, Anthopleurin-A, AP-A, ApA, PCR3-3,4, Toxin PCR7.
What is the protein family that this protein belongs to?
Belongs to the sea anemone sodium channel inhibitory toxin family. Type I subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: RS17_FRATF
Sequence: MSDKTRLLEGKVSSVAMDKTVVVRAERYVKHPLYGKFVKKTTKYYVHDENNECKEGDVIKFKETRPYSKTKKWCLVDIIHREK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.