PharMolix/UniProtQA huggingface dataset:
Protein: EFG_TERTT
Sequence: MARKTPIARYRNIGICAHVDAGKTTTTERVLFYTGLSHKIGEVHDGAATMDWMEQEQERGITITSAATTCFWAGMEQQFDQHRINIIDTPGHVDFTIEVERSLRVLDGAVVVLCGSSGVQPQTETVWRQANKYEVPRMVFVNKMDRAGANFLRVVEQLKDRLGATAVPLQMTIGSEDEFKGIVDLIEMKAILWNEADQGMTFDRADIPADMLEECEELREQMVEAAAEANEELMEKYLEEGELTNDEIKKGIRLRTLANEIVPVLGGSAFKNKGVQAMLDAVIEYLPAPTEVKAIQGTLEDGETVAERHADDTEPFSALAFKIATDPFVGTLTFFRVYSGKLESGTALLNSVKGKKERIGRMVQMHANSREEIKEVLAGDIAAAIGLKDTTTGDTLCAENSFIVLERMEFPEPVISVAVEPKSKADQEKMGIALGKLAQEDPSFRVRTDEETGQTIISGMGELHLDILVDRMRREFKVEANIGKPQVAYRERITKTSEIEGKFVRQSGGRGQFGHVWIRFEPAEDGDAEGLEFVNEIVGGVVPKEYIPAVEKGISEQMQNGVVAGYPLLGLKATIYDGSYHDVDSNEMAFKIAASMATKKLAQHGGAVLLEPMMKVEVVTPEENMGDVVGDLNRRRGLIQGMDENPSGKVVNAEVPLAEMFGYATALRSATQGRATFTMEFERYAEAPSNIAEEIIAKNKTGE
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIM_ALKCK
Sequence: MELVRQNNPLIHCMTNDVVMNFTANGLLAIGASPVMAFSAAETEDMASVADALLLNIGTPSNEGVDSMVLAGKAANRAGKPVIFDPVGVGATPFRNEISKRILNEVDVAVVRGNAGEIAALLGQAGTVKGVDGKINADVKELCLQAAKALRTVVVVTGEVDAVSNGEQLVAVANGHEWLTKVVGTGCLLGGVIAAYAAVQPNSLVDAAVEALAFYGVCAEQAYEQTKKEGIGSFQQTFLNELGNMTDEKAAALKRVEQIC
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: PMVK_DROME
Sequence: MMKIVLISGKRKCGKDYISERLQRRLGSRSCIVRISEPIKSEWARKLQLDLDALLGDGPYKEKYRRDMIVWSDEVRAQDYGYFCRVAMEEALSRQQTPYILVSDVRRKNDIRWFRETYGPERVITLRLTSRPETRSARGWTFTAGIDDVPSECDLDDLADGFDVVLANDEELDQEAIDILLDRLQLQYR
What are the official names of this protein?
Phosphomevalonate kinase, PMKase.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: FDHE_SALPK
Sequence: MSIRIIPQDELGSSEKRTADMIPPLLFPRLKNVYNRRAERLRELAENNPLGDYLRFAALIAHAQEVVLYDHPLEMDLTARIKEANDQGKPPLDIHVLPRDKHWQKLLHSLIAELKPEMNGPALAVIENLEKASEQELEQMASALFASDFASVSSDKAPFIWAALSLYWAQMASLIPGKARAEYGEARQYCPVCGSMPVSSMVQIDTTQGLRYLHCNLCETEWHVVRVKCSNCEQSRDLHYWSLENEQAAVKAESCGDCGTYLKILYQEKDPKVEAVADDLASLVLDARMEQEGFARSSINPFLFPGEGE
What is the function of this protein?
Necessary for formate dehydrogenase activity.
What are the official names of this protein?
Protein FdhE.
What is the protein family that this protein belongs to?
Belongs to the FdhE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRSA_GEOKA
Sequence: MKKWMMAAAVVSLMALSACSNDGSEAIVETKNGNITKDEFYNEMKERVGKSVLRDLIDEKVLSKKYKVTDEEIDREIERIKEAYGTQYDLAVQQNGEKVIREMVKLDLLRTKAAVEDIKVTEKELKEYYDNYKPKIRASHILVKDEKTAKEVKAKLDKGEDFSKLAKEYSQDPGSASNGGDLGWFGPGKMVKEFEEAAYKLKVGEVSDPVKTDYGYHIIKVTDKEKKKSFNEMKDEIAFEVKRNKLDPATMQSKVDKLVKDAGVEIKDKDLQDVIEQQGKQ
What is the function of this protein?
Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.
What are the official names of this protein?
Foldase protein PrsA.
What is the protein family that this protein belongs to?
Belongs to the PrsA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: TEG7_EBVA8
Sequence: MAFYLPDWSCCGLWLFGRPRNRYSQLPEEPETFECPDRWRAEIDLGLPPGVQVGDLLRNEQTMGSLRQVYLLAVQANSITDHLKRFDAVRVPESCRGVVEAQVAKLEAVRSVIWNTMISLAVSGIEMDENGLKALLDKQAGDSLALMEMEKVATALKMDETGAWAQEISAVVSSVTAPSASAPFINSAFEPEVPTPVLAPPPVVRQPEHSGPTELALT
What is the function of this protein?
Plays several roles during the time course of infection, including egress of virus particles from the perinuclear space and secondary envelopment of cytoplasmic capsids that bud into specific trans-Golgi network (TGN)-derived membranes.
What are the official names of this protein?
Tegument protein UL51 homolog.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae UL51 family.
What are the subcellular locations of this protein?
Virion tegument. Host cytoplasm. Host Golgi apparatus.
Protein: DAD3_KLULA
Sequence: MSSELTPLQRSVLDKYRFLAESLRELSETLSDLNNTHEDSKPEAILQEMREIEVKISLVSTLLKGSVYSLVIQRRMDHQQKPSDL
What is the function of this protein?
Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation.  The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore (By similarity).
What are the official names of this protein?
DASH complex subunit DAD3, Outer kinetochore protein DAD3.
What is the protein family that this protein belongs to?
Belongs to the DASH complex DAD3 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Associates with the mitotic spindle and the kinetochore.
Protein: CYB6_AMPOP
Sequence: MGFIYDWCEERLELQSIADDILSKFVPSHVNIFYCFGGIVLTCFIIQAATGFAMTLYYRPNVVEALSSVTYITNEVSFGWLVRSIHRTSSGLMVLVLLLHVSRVYLTAGFKKPRELTWISGVILAICTVSFGVTGYSLPWDQVGYWACKIVTATPEALNNVFPSLGTVFVTLLVGGTSVGQPTXTRFYQAHTFILPLVTLALLLTHFLMIRKQGISGPL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PCPD_SPHCR
Sequence: MTNPVSTIDMTVTQITRVAKDINSYELRPEPGVILPEFTAGAHIGVSLPNGIQRSYSLVNPQGERDRYVITVNLDRNSRGGSRYLHEQLRVGQRLSIVPPANNFALVETAPHSVLFAGGIGITPIWSMIQRLRELGSTWELHYACRGKDFVAYRQELEQAAAEAGARFHLHLDEEADGKFLDLAGPVAQAGQDSIFYCCGPEAMLQAYKAATADLPSERVRFEHFGAALTGEPADDVFTVVLARRSGQEFTVEPGMTILETLLQNGISRNYSCTQGVCGTCETKVLEGEPDHRDWVLSDEKKASNSTMLICCSLSKSPRLVLDI
What is the function of this protein?
Involved in the degradation of the xenobiocide pentachlorophenol (PCP) (PubMed:19325743, PubMed:23676275).  Catalyzes the reduction of tetrachlorobenzoquinone (TCBQ) to yield tetrachlorohydroquinone (TCHQ) (PubMed:19325743, PubMed:23676275).  Also able to reduce 2,6-dichloroindophenol (DCIP) (PubMed:23676275).
What are the official names of this protein?
Tetrachlorobenzoquinone reductase, TCBQ reductase.
What is the protein family that this protein belongs to?
Belongs to the PDR/VanB family.
Protein: RSMA_ECOLU
Sequence: MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEIGPGLAALTEPVGERLDKLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTFNFGELAEKMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRLSVMAQYYCNVIPVLEVPPSAFTPPPKVDSAVVRLVPHATMPHPVKDVRVLSRITTEAFNQRRKTIRNSLGNLFSVEVLTGMGIDPAMRAENISVAQYCQMANYLAENALLQES
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPH_MANES
Sequence: MNPLISAASVIAAGLAVGLASIGPGVGQGTAAGQAVEGIARQPEAEGKIRGTLLLSLAFMEALTIYGLVVALALLFANPFV
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, chloroplastic, ATP synthase F(0) sector subunit c, ATPase subunit III, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: TRMB_BREBN
Sequence: MRLRNIPGAEAALREYPTFVDNPLFYKGNWKERFGNNNPIHVEIGCGKGRFINTLAERHPDINFIAVELKAEVVLRAVQRTEYKAIPNLAFVQYDASKLTELFADHEISRIYLNFSDPWPKTRHAKRRLTYKSFLNTYRQVLVADGELHMKTDNENLFEFSLNQFAAERFQMRNITFDLHQSKLAADNVMTEYEERFSSRGQRIYRVEASCVIK
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: MTNB_GLUOX
Sequence: MQNLKVDESWGNACRQIVQAGQRMDQRGWVPATAGNLSCRLPDGRIAITRSGGHKGFLTDSDVIEITPDGVPVDPANRASAETLLHTQLYAHDPAIGAVLHGHSVAATILSMDEPSDAITLAGYEVLKVFEGQTTHDTSLELPLFHNDQDIARLATVVAPKLSDMRLGYLIRGHGVYVWGKDMFTALARLEGLEFLLACELARLQKKA
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
What are the official names of this protein?
Methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
Protein: RECO_AZOSB
Sequence: MAVKQRIDQQSAWVLHTLPWRETSLIVEVFSRDHGRLALVAKGARRPHSAFRGVLMAFQPLLMDWSGGGEVRTLVRAEWQGGQPLLTGQALLCGYYLNELLVKLTPRDDPHPNLFVAYADAVRELGLGRPPPPVLRQFELALLQELGYGIELVHDVQSGEAVRGDATYAYIIEGGPAALDAPGDAPPDLPVVSGQTLLDMAAGDFSRSETLAQSKRLLRVLINHYLGGQPLQSRRVLQELLEL
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: USH1C_BOVIN
Sequence: MDRKVAREFRHKVDFLIENDAEKDYLYDVLRMYHQTMDVAVLVGDLKLVINEPSRLPLFDAIRPLIPLKHQVEYDQLTPRRSRKLKEVRLDRLHPEGLGLSVRGGLEFGCGLFISHLIKDGQADSVGLQVGDEIVRINGYSISSCTHEEVINLIRTKKTVSIKVRHIGLIPVKSSPDEPLKWQYVDQFVSESGGGRSSLGSPGSQENKEKKVFISLVGSRGLGCSISSGPIQKPGIFISHVKPGSLSAEVGLETGDQIVEVNGIDFSNLDHKEAVNVLKSSRSLTISIVAGAGRELFMTDQERLAEVRQRELQRQELLMQKRLAMESNKILQEQQEMERQRKKEIAQKAAEENERYRKEMEQIVEEEEKFRKQWEEDWGSKEQLRSPKTITAEVHPIPLRKPKYDLGVDPEFDPADDLDGGTNKRGEQDFRKYEEGFDPYSMFTPEQIMGKDVRLLRVKKEGALDLALEGGVDSPIGKVVVSAVYEGGAAERHGGIVKGDEIMAINGKIVTDYTLAEAEAALQKAWNQGDWIDLVVAVCPPKEYDDELTFF
What is the function of this protein?
Anchoring/scaffolding protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells.  Required for normal development and maintenance of cochlear hair cell bundles (By similarity).  As part of the intermicrovillar adhesion complex/IMAC plays a role in brush border differentiation, controlling microvilli organization and length.  Probably plays a central regulatory role in the assembly of the complex, recruiting CDHR2, CDHR5 and MYO7B to the microvilli tips (By similarity).
What are the official names of this protein?
Harmonin, Usher syndrome type-1C protein homolog.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Cell projection, microvillus. Note=Colocalizes with F-actin. Detected at the tip of cochlear hair cell stereocilia (By similarity). Enriched in microvilli of the intestinal brush border (By similarity).
Protein: CINV1_ARATH
Sequence: MEGVGLRAVGSHCSLSEMDDLDLTRALDKPRLKIERKRSFDERSMSELSTGYSRHDGIHDSPRGRSVLDTPLSSARNSFEPHPMMAEAWEALRRSMVFFRGQPVGTLAAVDNTTDEVLNYDQVFVRDFVPSALAFLMNGEPDIVKHFLLKTLQLQGWEKRVDRFKLGEGVMPASFKVLHDPIRETDNIVADFGESAIGRVAPVDSGFWWIILLRAYTKSTGDLTLSETPECQKGMKLILSLCLAEGFDTFPTLLCADGCSMIDRRMGVYGYPIEIQALFFMALRSALSMLKPDGDGREVIERIVKRLHALSFHMRNYFWLDHQNLNDIYRFKTEEYSHTAVNKFNVMPDSIPEWVFDFMPLRGGYFVGNVGPAHMDFRWFALGNCVSILSSLATPDQSMAIMDLLEHRWAELVGEMPLKICYPCLEGHEWRIVTGCDPKNTRWSYHNGGSWPVLLWQLTAACIKTGRPQIARRAVDLIESRLHRDCWPEYYDGKLGRYVGKQARKYQTWSIAGYLVAKMLLEDPSHIGMISLEEDKLMKPVIKRSASWPQL
What is the function of this protein?
Cytosolic invertase that specifically cleaves sucrose into glucose and fructose and is involved in the regulation of multiple tissue development including primary root elongation, root hair growth, leaf and silique development, and floral transition (PubMed:17220200, PubMed:19470642, PubMed:21441406, PubMed:25256212).  Is involved in osmotic stress-induced inhibition on lateral root growth by controlling the concentration of hexose in cells (PubMed:17508130).  May regulate sugar-mediated root development by controlling sucrose catabolism in root cells (PubMed:17220200).  Contributes to carbon partitioning and cellulose biosynthesis in seedlings (PubMed:29569779).
What are the official names of this protein?
Alkaline/neutral invertase CINV1, AtCINV1, Alkaline/neutral invertase G, A/N-INVG, Cytosolic invertase 1, AtCYT-INV1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 100 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Note=Detected in membrane and nucleus when associated with PIP5K9.
Protein: RF1_MYCAP
Sequence: MEKTMFKSLSEIKQSYLELLKKIDDPEVISNIKEYSAINKEIAKIREISEKFITYENILKDVEQAKIMLESKNEEEVEFAKMIIDENSLKLDELEEKLKILILPQDENDDKNIIVEIRGAAGGDEANIFAGDLFRMYSKFADELGFRLKILSTNSASAGGFSQIVFSIKGEKAYSKFKFESGVHRVQRVPVTESQGRIHTSTTTVTVMPEIDDSVEIEIKPSDLKIDVFRSSGAGGQSVNTTDSAVRITHLPTNIVVTSQDERSQIANRETALTILKSKLYDLEMQKKAEEESGYRKLAGHGDRSEKIRTYNYPQDRVTDHRISFSTSLKPIMEGKLTPIIDALLAEEQNQKIKESGF
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRDB_BACP2
Sequence: MLNVELPGLSLKNPIIPASGCFGFGREFASLYDLSVLGSIMIKATTLEPRFGNPTPRVAETGAGMLNAIGLQNPGLKGVLENELPWLEQFDTPIIANVAGSQVDDYVEVAEQISQAKNVHALELNISCPNVKTGGIAFGTDPQMAAALTKAVKDVSSVPVYVKLSPNVANIVEIAQAIESAGADGLTMINTLIGMRLDLKTGKPILANKTGGLSGPAIKPVAVRMVHEVSQAVSIPIIGMGGVQNAEDVLEFLLAGASAVAVGTANFVNPFICPEIIEELPNVLAAYGYSSVEECIGRSWKHEALAHHRA
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit, DHOD B, DHODase B, DHOdehase B, Dihydroorotate oxidase B, Orotate reductase (NADH).
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL332_STAAB
Sequence: MFNVRVNVTLACTECGDRNYITTKNKRNNPERIEMKKYCPRLNKYTLHRETK
What are the official names of this protein?
50S ribosomal protein L33 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: SIP5_ASPFC
Sequence: MGNSQTKEFRPPLSSSNRRSHQWGSSSSHGRSPYSDRHHAESSRSRGSRPDLSILGIGGSSERDVATLEHRRETKQEREARRLEKERAARVKERERSMREEHVDGGYLVTQGVYVGTEDFNKAVTRQLMIERRLAPFWRGLNDFSESWTEHQLMAAARGLPIPPPDEIPPELEYKNPPKLSGDGKEPSIQHLMVPITSRSQSYGSEASQSSTPAHSLPAPVSPIASGTSTSPLFRSRAKTLASLTTSKLGSQSDSTPKEIHLPEDPFVNGQPIEAYLYKDATECPICFLYYPPYLNRTRCCDQPICSECFVQIKRPDPHPPEHGEAEPNAAAAEGDRQDNQDCQLVSEPAACPFCVQPEFGVTYTPPPFRRGLVYATDPTLRPNFTSPVSSTSSLASANASPGTGRRRATSLSANDPAVITTDRVRPDWAQKLANARAHAARRSAAATALHTAAYLMNSTASGNESRNFSLGRRGVMRRTGQSETPSASSRSGSPALQALAFLTDRRTPGHDTDSAEEGTGNLAPPRNSSRRSRIDDLEEMMMMEAIRLSLASEEERRKKAEKEARKEAKRREKENKKAEKAARKHGFYSNNASSSALDVPSDARLGRVASTSSSITGEDASPSKGKEVDRTSPAATAASSQSSTEIASESMTINPHPNVVEQGPSAQSSMAQLSPRELPKPSHLRQVSSASSSFSSLVESTGEDHSGAYDGNASSTEPLFNFRSLAAVIGDEDKGDGTAEHVEDTSSKPSAEGSASSTAPVADEMPGQSTTPADPIAVKTVAEDRDCLMPKELETQSVEITSATRNAEATT
What is the function of this protein?
May negatively regulate the snf1 kinase.
What are the official names of this protein?
Protein sip5.
What is the protein family that this protein belongs to?
Belongs to the SIP5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SC61A_HEMAM
Sequence: MGIKFLEVIKPFCAVLPEIQKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIGVGDTPKDRALFNGAQKLFGMIITIGQAIVYVMTGMYGDPSEMGAGICLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTVNTGRGTEFEGAIIALFHLLATRTDKVRALREGFYRQNLPNLMNLIATVFVFAVVIYFQGFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSTRFSGNFLVNLLGTWSDATSGGPARAYPVAGLCYYLSPPESFGSVLDDPVHAGIYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGGLSVMADFLGAIGSGTGILLAVTIIYQYFEIFVKEQSEVGSMGALLF
What is the function of this protein?
Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across the endoplasmic reticulum (ER).  Forms a ribosome receptor and a gated pore in the ER membrane, both functions required for cotranslational translocation of nascent polypeptides.  May cooperate with auxiliary protein SEC62, SEC63 and HSPA5/BiP to enable post-translational transport of small presecretory proteins.  The SEC61 channel is also involved in ER membrane insertion of transmembrane proteins: it mediates membrane insertion of the first few transmembrane segments of proteins, while insertion of subsequent transmembrane regions of multi-pass membrane proteins is mediated by the multi-pass translocon (MPT) complex.
What are the official names of this protein?
Protein transport protein Sec61 subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Localizes exclusively in granular structures in the endoplasmic reticulum (ER).
Protein: MALQ_CHLCV
Sequence: MTPFSKALRCIQNSPAKQSWKTLGIMPKHGICLPLFSLHTRNSCGIGEFLDLIPMISWCRKHGFQIIQILPINDSGEDSSPYNSISSVALNPLYLSLASLPHAQSVAYANAKLRTMQQLSKLPYVHYPQVKAAKWEFLRDYYQYVVKIGALKDEDFEIFCEKEKYWLRPYTVFRSIKYHLKGAPVNNWPKAYTDIKNFTEFEKQFQDECSFFSYLQYLCFQQMSQVKAFADDNHVFLKGDLPILISKDSCDVWYYRQFFSSSGSAGAPPDIYNTEGQNWHLPIYNMHNLVQDNYTWWKARLRYAENFYSLYRLDHIVGLFRLWVWDTSGNGKFQPDDPKEYLPQGTDILTQILRASRMLPIGEDLGSVPTDVKETLVKLGICGTRIPRWERNWEGDGNFIPLGEYSPLSVTSLSTHDSDTLALWWRHAPKEAQKFAQFLGMFFTPVLAEEDQKHILTLSHKTSSIFHINLINDYLALCPDLVSNNLKYERINMPGTVSKNNWVYRIKPSVEEILTHDAFNANIADIFSKI
What are the official names of this protein?
4-alpha-glucanotransferase, Amylomaltase, Disproportionating enzyme, D-enzyme.
What is the protein family that this protein belongs to?
Belongs to the disproportionating enzyme family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_STRMU
Sequence: MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKILPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: OPPF_STRMU
Sequence: MTENRKKLVEVKNVSLTFNKGKANQVKAIDNVSFNIYEGEVFGLVGESGSGKTTIGRAILKLYNIDKGEIDFEGETISKLKGKSLFNFRKKAQMIFQDPQASLNSRMKVRDIIAEGLDVHKLVKNKADRDAKVQDLLDLVGLNKDHLTRYPHEFSGGQRQRIGIARALAVEPKFIIADEPISALDVSIQAQVVNLMQKLQHEQGLTYLFIAHDLSMVKYISDRIGVMHWGKIVEIGTSDEVYHHPIHPYTQSLLSAVPEPDPVLERQRIHKVYDPVDELDGQEREMREITPGHFVLATEEEAKAYKKK
What is the function of this protein?
Part of the binding-protein-dependent transport system for oligopeptides.  Probably responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Oligopeptide transport ATP-binding protein OppF.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL14_DINSH
Sequence: MIQMQTNLDVADNSGARRVQCIKVLGGSKRKYASVGDIIVVSVKEAIPRGRVKKGDVRKAVVVRTAKEVRREDGTAIRFDRNAAVILNNNNEPIGTRIFGPVVRELRAKNFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: END4_OLEA2
Sequence: METISRQNKPQQQLIGAHMSAAGGVHKAVERAEAAGATALQVFTRNQRQWNAPPLEEHDAELFTAAVRRWGGYPVSSHASYLINPAADTPEGAERSVALMADELQRAGRLGIEMVVVHPGAHKGQGEAAGAALAAARLDEALERCGSPAVMVLLENTAGQGTMLGASFAGLAAVIEASRMPERYGICLDTAHAFGAGYDLRDAALYDAAIRELDVCAGLDRLRLVHANDSLTGLGSRRDRHTHIGQGELGEAAFRLLMRDERLHHVPKVLETPKGKGPEEDMMNMAVLRRLACP
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: MURE_SYNWW
Sequence: MKLVELIKNLTIELQDGPLDREISGIAYDSRRVKPGDLFICISGLKSDGHLFAGQAIENGAVAVLAERQLDTGGKATLLTTPDTRSALALLAANYYGRPSKSIRVVAVTGTNGKTTTTDLIKAILEEAGKKTAIMGTLYAQVGEIQREMQHTTPEALEIESFMALCREEKADYIVMEVSSHALQLQRVAEIDFNVAVFTNLTQDHLDFHQNMDNYRAAKLQLFQMIKEEKQNYAIINIDDPWAEEIFQAATIPCRSYGIKKRSDYQAGELKIDLDGSSFRLHYGDNSLMINMKLIGLFSIYNALAAISFALQEGIDPGLIQSALARVEGVPGRFEKVDCGQDFAVIVDYAHTPDGLENILQTSRELGKKRLICVFGCGGDRDRSKRPLMGEIAAKYSDFCVVTSDNPRSEDPHAIIAEIIPGMDKVEKSRYAIIVDRREAIRHAIHLARTGDLVVIAGKGHENYQLVKDQVLEFDDRKVAAELLRGKVK
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPB_LEPCP
Sequence: MFDYQQPDARGHFGIYGGSFVAETLSHALDELNAAYERYRHDPEFIAEFRNELAHFVGRPSPVYHAARMSREVGGAQIYLKREDLNHTGAHKINNTIGQALLARRMGKPRVIAETGAGQHGVATATICARYGMECVVYMGSEDVKRQSPNVYRMNLLGARVVPVESGSKTLKDALNEAMRDWVTNVENTFYIIGTVAGPHPYPAMVRDFQRVIGDECLVQMPALAGRQPDAVVACVGGGSNAMGIFYPYIPHEGVRLIGVEAAGEGMESGKHSASLQRGSPGVLHGNRTYVLQDANGQITETHSVSAGLDYPGVGPEHAYLKDIGRAEYVGITDAEALQAFHYLCRAEGIIPALESSHAVAYAMKLAKTMRPDQHVLVNLSGRGDKDIGTVADLSGADFYCRPSCRGQSVKGGDPSVVEIQRKAGGVQ
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.