PharMolix/UniProtQA huggingface dataset:
Protein: BMP4_DAMDA
Sequence: MIPGNRMLMVVLLCQVLLGGATHASLIPETGKKKVAEIQGHAGGRRSGQSHELLRDFEATLLQMFGLRRRPQPSKSAVIPDYMRDLYRLQSGEEEEEEQIQGIGLEYPERPASRANTVRSFHHEEHLENIPGTSENSAFRFLFNLSIPENQVISTAELRDFREQVDQGPDWERGFHRINIYEVMKPPAEAVPGHLITRLLDTRLVHHNVTRWETFDVSPAVLRWTREKQPNYGLAIEVTHLHQTRTHQGQHVRISRSLPQGSGDWAQLRPLLVTFGHDGRGHALTRHRRAKRSPKHHPQRARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVNSSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR
What is the function of this protein?
Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including neurogenesis, vascular development, angiogenesis and osteogenesis (By similarity).  Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).  Initiates the canonical BMP signaling cascade by associating with type I receptor BMPR1A and type II receptor BMPR2.  Once all three components are bound together in a complex at the cell surface, BMPR2 phosphorylates and activates BMPR1A.  In turn, BMPR1A propagates signal by phosphorylating SMAD1/5/8 that travel to the nucleus and act as activators and repressors of transcription of target genes.  Can also signal through non-canonical BMP pathways such as ERK/MAP kinase, PI3K/Akt, or SRC cascades.  For example, induces SRC phosphorylation which, in turn, activates VEGFR2, leading to an angiogenic response (By similarity).
What are the official names of this protein?
Bone morphogenetic protein 4, BMP-4.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: SPAT1_RAT
Sequence: MSLNPSRPSSSELVELHVFYVPEGSWNYKLNTISIEVINNFISAGFIRVSPQLTLQALRERLGEFLGVDAVAEKFLFLKCIGNNLAVVKEKQESELKLKSFAPPYALQPELYLLPVIDHLGNVYSASTVNLDEQQSVDDTMEIDGTIHRPDSLSLSKDEPGDPSLLENTWRDFPNHEEAEESQPTQQHFGNPRLPGSLEESDDCLGNVKSPFLWKNNDEDEGEEDDKATINRRQAKLVCDKEHSALPDLIDFPSFPSQRVSSRLVDTSLLKIEREKIIEQMKQVKEERKYLENIREELIKKVEKLFEQSKSKRYHACDSWKKKYFDTKKVTASLEEVLTKLREDLELYYKKLLMQLEAREIKMRPRNLANISDSKNYLIIQITEVQHAIDQLKRKLDTDKMKLILEVKMRKQAASDLQTLRADLTQKKMGTPFRSPIFSGSVPT
What are the official names of this protein?
Spermatogenesis-associated protein 1.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, acrosome.
Protein: COAD_PYRFU
Sequence: MKKKYKKVVVGGTFDRLHLGHKALLRKAFEVGEIVYIGLTSDEMIKEKQYSERILPYEKRLLDLIKFLEVNKYRNYRIMKIHNAIGFTTKIKSLEAIVVSEETYKGAVLVNKAREELGLRPLDIVVIPIIRSRLGCKISSSLIRAGLIDPFGNPIRREEK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEC2_MAGO7
Sequence: MASSRDRAYVTVYSPTLLTWVYDYYVLGFNLRYIWGCPTDAVLLPFFAENFSRRHLDVGVATGYLPARVLASPWRRAAAHRQHLTLLDINANSLRASDARVRAAAPGIETTCVEADVVADLPPVLASVVEEERARVEKAGGEAGSSSRSCLYDSISMFNLFHCVPGGPAKLRAISTYKALLADHGVLSGCTVLGERHATGWFSRWYLRLYNRKGIFNNINDTREEFEEVLNKEFEEVDTWMFGMVLLFRASKPRREGSGYVDLLA
What is the function of this protein?
O-methyltransferase; part of the gene cluster that mediates the biosynthesis of nectriapyrone and its analogs phomopyrone A, acropyrone and zaepyrone (PubMed:30443971).  The nectriapyrone biosynthetic gene cluster consists of two genes, the highly reducing polyketide synthase NEC1 that produces a demethylated analog of nectriapyrone from one unit of acetyl-CoA and one unit of malonyl-CoA; and the O-methyltransferase NEC2 that further methylates the NEC1 product to yield nectriapyrone (PubMed:30443971).  Nectriapyrone is further hydrolyzed to nectriapyrone D, also known as gulypyrone B, by an unidentified hydrolase localized outside the nectriapyrone cluster (PubMed:30443971).
What are the official names of this protein?
O-methyltransferase NEC2, Nectriapyrone biosynthesis cluster protein 2.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: NACC1_MOUSE
Sequence: MAQTLQMEIPNFGNSILECLNEQRLQGLYCDVSVVVKGHAFKAHRAVLAASSSYFRDLFNSSRSAVVELPAAVQPQSFQQILTFCYTGRLSMNMGDQFLLIYTAGFLQIQEIMEKGTEFFLKVSSPSCDSQGLHPEEAPSSEPQSPVAQTLGWPACSTPLPLVSRVKTEQELDSVQCTPMAKRLWDSSQKEAGGSGGNNGSRKMAKFSTPDLALNRMPQPLSMATATAAVAVVAVGGCVSGPSMSERTSPGTSSAYTSDSPSSYHNEEDEEEDAGEEGTDEQYRQICNMYTMYSMLNVGQTAEKVEALPEQVVLESRSRIRVRQDLASLPAELINQIGNRCHPKLYDEGDPSEKLELVTGTNVYITRAQLMNCHVSAGTRHKVLLRRLLASFFDRNTLANSCGTGIRSSTNDPRRKPLDSRVLHAVKYYCQNFAPNFKESEMNAIAADMCTNARRVVRKSWLPKTKPLHLVEGDNYSSFISDTCKIEPDMMSMEHSFETASHDGEAGPSAEVLQ
What is the function of this protein?
Functions as a transcriptional repressor.  Seems to function as a transcriptional corepressor in neuronal cells through recruitment of HDAC3 and HDAC4.  Contributes to tumor progression, and tumor cell proliferation and survival.  This may be mediated at least in part through repressing transcriptional activity of GADD45GIP1.  Required for recruiting the proteasome from the nucleus to the cytoplasm and dendritic spines.  Involved in the acute behavioral and neurological responses to cocaine and amphetamines.
What are the official names of this protein?
Nucleus accumbens-associated protein 1, NAC-1, BTB/POZ domain-containing protein 14B.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Distribution in the cytoplasm is dependent on phosphorylation.
Protein: RS13_CHLCV
Sequence: MPRIIGIDIPAKKKLKISLTYIYGIGPALSEEIIAKLQLNPEARAVELTEEEIGRLNSLLQSEYVVEGDLRRRVQSDIKRLISIHAYRGQRHRLSLPVRGQRTKTNSRTRKGKRKTVAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: RSMH_CLOB6
Sequence: MEFKHISVLLEETIDSLNIKEDGVYVDCTLGGGGHSKEILKKLSHKGKLIGIDQDTSAIKAAKERLKDYENVIYVHNNFYNIDSILEELDIDKVDGIIMDLGVSSYQLDEASRGFSYMKDAPLDMRMNREENLSAYGVINNYKEEELFKILKNYGEEKFSRKIARFIVEKRTENPIETTGELVEIIRKAIPAKFQREGHPAKRTFQAIRIEVNKELQILNKAIEDSVNRLNKDGRLSIITFHSLEDRIVKVKFKELEKPCTCPPSFPICVCGKEPQIKIITKKPIEPSKEEKEINSRSRSAKLRVCRKI
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPAM_PEA
Sequence: MEFSVRAAELTTLLESRITNFYTNFQVDEIGRVVSVGDGIARVYGLNEIQAGELVEFASGVKGIALNLENENVGIVVFGSDTSIKEGDLVKRTGSIVDVPAGKAMLGRVVDALGVPIDGRGALSDHERRRVEVKAPGIIERKSVHEPMQTGLKAVDSLVPIGRGQRELIIGDRQTGKTAIAIDTILNQKQMNSRATSESETLYCVYVAIGQKRSTVAQLVQILSEANALEYSILVAATASDPAPLQFLAPYSGCAMGEYFRDNGMHALIIYDDLSKQAVAYRQMSLLLRRPPGREAFPGDVFYLHSRLLERAAKRSDQTGAGSLTALPVIETQAGDVSAYIPTNVISITDGQICLETELFYRGIRPAINVGLSVSRVGSAAQLKAMKQVCGSLKLELAQYREVAAFAQFGSDLDAATQALLNRGARLTEVLKQPQYAPLPIEKQILVIYAAVNGFCDRMPLDKIAQYERDILSTIKQELLQSLKGGLTGERKIEPDAFLKEKALSLI
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Subunits alpha and beta form the catalytic core in F(1).  Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.  Subunit alpha does not bear the catalytic high-affinity ATP-binding sites (By similarity).
What are the official names of this protein?
ATP synthase subunit alpha, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane. Note=Peripheral membrane protein.
Protein: XNI_YERPS
Sequence: MQIHLLIVDALNLIRRIHAVQGSPCVKACQHALQQLIQHSQPSHAVAVFDEDDRSDSWRHQCLPDYKAGRSPMPDNLQQEMPLIRQAFNELGVACWHSPGNEADDLAATLVVKVAGAGHQVTIVSTDKGYCQLLAPNVQIRDYFQKRWLDMPFVKQEFGVLPRQLPDYWGLAGISSSKIPGVAGVGAKTATLLLQQADTLEVLYQNLESIPEKWRKKLQQHQQMAFTCKQIATLKTDLLLSGNLQQLRLKK
What is the function of this protein?
Has flap endonuclease activity.  During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.
What are the official names of this protein?
Flap endonuclease Xni, FEN.
What is the protein family that this protein belongs to?
Belongs to the Xni family.
Protein: MUTS_PSEAB
Sequence: MTDLSQHTPMMQQYFKLKHQHPDQLMFYRMGDFYELFYEDAKKAAKLLDITLTARGQSGGKAIPMAGIPFHSAEGYLAKLVKLGESVAICEQIGDPATSKGPVERQVVRIITPGTVSDEALLDERRDNLLAAILGDERLFGLAVLDITSGRFSVQEIKGWETLLAELERLNPAELLIPDDWPQGLPAEKRRGVRRRAPWDFDRDSAHKSLCQQFGTQDLKGFGCQNLTLAIGAAGCLLAYAKETQRTALPHLRSLRHDRLDDTVILDGASRRNLELDINLSGGRENTLQSVVDRCQTAMASRLMSRWLNRPLRDRAVLEARQESIACLLERYRFENLQPQLKEIGDLERILARIGLRNARPRDLARLRDALAALPDLQNAMTELEAPHLQALATTIGTYPELAELLAKAIIDNPPAVIRDGGVIKTGYDAELDELQALSENAGQFLMDLEAREKARTGLPNLKVGYNRIHGYFIELPRVQAEQAPADYIRRQTLKGAERFITPELKAFEDKALSAQSRALAREKALYEELLERLIGHLAPLQDSASALAELDVLANLAERALNLDLNRPRFVEHTCLHIEQGRHPVVEQVLETPFVANDLALDADTRMLVITGPNMGGKSTYMRQTALIVLLAHIGSFVPAARCELSLVDRIFTRIGSSDDLAGGRSTFMVEMSETANILHNATDKSLVLMDEVGRGTSTFDGLSLAWAAAEDLARTRAFTLFATHYFELTVLPESQPAVANVHLNATEHNERIVFLHHVLPGPASQSYGLAVAQLAGVPTPVIQRAREHLKRLETTSLPHEMPSQQSGKPASPMQSDLFASLPHPVIDELSRINPDDISPRQALDLLYAWKMRV
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: AAR2_YEAST
Sequence: MNTVPFTSAPIEVTIGIDQYSFNVKENQPFHGIKDIPIGHVHVIHFQHADNSSMRYGYWFDCRMGNFYIQYDPKDGLYKMMEERDGAKFENIVHNFKERQMMVSYPKIDEDDTWYNLTEFVQMDKIRKIVRKDENQFSYVDSSMTTVQENELLKSSLQKAGSKMEAKNEDDPAHSLNYTVINFKSREAIRPGHEMEDFLDKSYYLNTVMLQGIFKNSSNYFGELQFAFLNAMFFGNYGSSLQWHAMIELICSSATVPKHMLDKLDEILYYQIKTLPEQYSDILLNERVWNICLYSSFQKNSLHNTEKIMENKYPELLGKDNEDDALIYGISDEERDDEDDEHNPTIVGGLYYQRP
What is the function of this protein?
Component of the U5 snRNP complex that is required for spliceosome assembly and for pre-mRNA splicing.  Involved in splicing pre-mRNA of the A1 cistron and other genes that are important for cell growth.
What are the official names of this protein?
A1 cistron-splicing factor AAR2.
What is the protein family that this protein belongs to?
Belongs to the AAR2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=This protein lacks a nuclear localization signal, it may interact in the cytoplasm with a component of spliceosomes via the leucine-zipper and then be transported into the nucleus.
Protein: PDS5A_HUMAN
Sequence: MDFTAQPKPATALCGVVSADGKIAYPPGVKEITDKITTDEMIKRLKMVVKTFMDMDQDSEDEKQQYLPLALHLASEFFLRNPNKDVRLLVACCLADIFRIYAPEAPYTSHDKLKDIFLFITRQLKGLEDTKSPQFNRYFYLLENLAWVKSYNICFELEDCNEIFIQLFRTLFSVINNSHNKKVQMHMLDLMSSIIMEGDGVTQELLDSILINLIPAHKNLNKQSFDLAKVLLKRTVQTIEACIANFFNQVLVLGRSSVSDLSEHVFDLIQELFAIDPHLLLSVMPQLEFKLKSNDGEERLAVVRLLAKLFGSKDSDLATQNRPLWQCFLGRFNDIHVPVRLESVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVTIITAAKRDLALVNDQLLGFVRERTLDKRWRVRKEAMMGLAQLYKKYCLHGEAGKEAAEKVSWIKDKLLHIYYQNSIDDKLLVEKIFAQYLVPHNLETEERMKCLYYLYASLDPNAVKALNEMWKCQNMLRSHVRELLDLHKQPTSEANCSAMFGKLMTIAKNLPDPGKAQDFVKKFNQVLGDDEKLRSQLELLISPTCSCKQADICVREIARKLANPKQPTNPFLEMVKFLLERIAPVHIDSEAISALVKLMNKSIEGTADDEEEGVSPDTAIRSGLELLKVLSFTHPTSFHSAETYESLLQCLRMEDDKVAEAAIQIFRNTGHKIETDLPQIRSTLIPILHQKAKRGTPHQAKQAVHCIHAIFTNKEVQLAQIFEPLSRSLNADVPEQLITPLVSLGHISMLAPDQFASPMKSVVANFIVKDLLMNDRSTGEKNGKLWSPDEEVSPEVLAKVQAIKLLVRWLLGMKNNQSKSANSTLRLLSAMLVSEGDLTEQKRISKSDMSRLRLAAGSAIMKLAQEPCYHEIITPEQFQLCALVINDECYQVRQIFAQKLHKALVKLLLPLEYMAIFALCAKDPVKERRAHARQCLLKNISIRREYIKQNPMATEKLLSLLPEYVVPYMIHLLAHDPDFTRSQDVDQLRDIKECLWFMLEVLMTKNENNSHAFMKKMAENIKLTRDAQSPDESKTNEKLYTVCDVALCVINSKSALCNADSPKDPVLPMKFFTQPEKDFCNDKSYISEETRVLLLTGKPKPAGVLGAVNKPLSATGRKPYVRSTGTETGSNINVNSELNPSTGNRSREQSSEAAETGVSENEENPVRIISVTPVKNIDPVKNKEINSDQATQGNISSDRGKKRTVTAAGAENIQQKTDEKVDESGPPAPSKPRRGRRPKSESQGNATKNDDLNKPINKGRKRAAVGQESPGGLEAGNAKAPKLQDLAKKAAPAERQIDLQR
What is the function of this protein?
Probable regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin.  May couple sister chromatid cohesion during mitosis to DNA replication.  Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair.
What are the official names of this protein?
Sister chromatid cohesion protein PDS5 homolog A, Cell proliferation-inducing gene 54 protein, Sister chromatid cohesion protein 112, SCC-112.
What is the protein family that this protein belongs to?
Belongs to the PDS5 family.
What are the subcellular locations of this protein?
Nucleus. Note=Associated with chromatin through most of the cell cycle. Dissociates from chromatin in late prophase, reassociates during late telophase.
Protein: RAMP3_CAVPO
Sequence: MGTRSRRPQLLWLLLLCGTCARVCGCNETRMLERLPRCGKTFAERMREVAVWKWCDLSQFIVFYESFTNCTEEETVVVGCYWPNPLAQGFITGVHRQFFSNCTVDRTHWEDPPDEVLIPLIAVPILLTVAMTGLVVWRSKRTDQLP
What is the function of this protein?
Plays a role in cardioprotection by reducing cardiac hypertrophy and perivascular fibrosis in a GPER1-dependent manner.  Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) and GPER1 to the plasma membrane.  Acts as a receptor for adrenomedullin (AM) together with CALCRL (By similarity).
What are the official names of this protein?
Receptor activity-modifying protein 3.
What is the protein family that this protein belongs to?
Belongs to the RAMP family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Membrane; Single-pass type I membrane protein. Note=Moves from intracellular puncta to the plasma membrane in a RAMP3-dependent manner.
Protein: FTHS_METS4
Sequence: MPTDIEIARAATLQPISAIAETLGIPDEALHPYGRHIAKIDHAHIASLEAKPEGKLVLVTAISPTPAGEGKTTTTVGLGDALNRIGKRTVICLREPSLGPCFGMKGGAAGGGRSQVVPMEAINLHFTGDFHAITSAHSLAAALIDNHIYWGNALGIDPRRVAWRRVVDMNDRSLRSIVQSLGGVANGYPREDGFDITVASEVMAVFCLARDLADLEARLGRIVVAESRERKPVTLADLKATGAMTVLLKDALQPNLVQTLEGSPALIHGGPFANIAHGCNSVIATRSGLRLGEYAVTEAGFGADLGAEKFIDIKCRQTGLSPSAVVIVATVRALKMHGGVEKKALGGENVAALEKGFANLQRHVENVRRFGLPVVVAVNHFHADTEAEHAALKALCRDRLDVQAITCRHWAEGGAGAEDLARAVVSLAEGGAPATPNFVYPEEAKLTDKIRTIAQTLYGAADIQVESKAAAKLAQFEKDGYGRLPVCMAKTQYSFSTDPGLIGAPSGHVVAVRDVRLSAGAGFVVVICGEIMTMPGLPKVPASEGIYLDANGQIEGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: YUBD_BACSU
Sequence: MKTKHYWVISLLAVLAVGPGLMSNTALSSVQGLVQKTVGTSVFTSVNPILIGNMAFALLVPAGPLLRKKFGARPVYLASLPVFILGSLLIACSGDIALMAAGRFLQGAATGVMLMIMIPMLVLSFPIERRNYALLVLIGGFYGSVIIGTILGTIATSCGHWRWLFFIFGTLSLIGVAVSYFFLHDEHHGAADQEQPLDRAGILLSVFLAAASAVSFIFLQKWGLSSGYVWIGFGVTLCLLIGLLIVEYKVKNPFISIKLMLLPKPVLGLLIIAAGTITVAVSLSAFQGLLRQMYDISQEHLILLSLTLLIGVAIAAILSALLYDKVGPGMLGIIGGLILVFVNFQWLHIQDRSSLYMFAALFIMLAAGTGLTVAAGLMGAAMGGPLPDLVKRMTAVQFLRLFVYMGVPILIGFFTKKDAARQSGSVQDSMMTAYHDLFFISFILSVLLVCLSFCMNATGMGHKLAHKPHDKAKTAPEKPAVSAQGLSKATVKSYKVINDTEYRNALRNLQK
What are the official names of this protein?
Uncharacterized MFS-type transporter YubD.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SLLB_LACMR
Sequence: DCPSGWSSYEGHCYRVFNEPKNWADAERFCKLQPKHSHLV
What is the function of this protein?
Interferes with one step of hemostasis (modulation of platelet aggregation, or coagulation cascade, for example).
What are the official names of this protein?
Snaclec LmrLEC-1.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: AIM36_YEAS1
Sequence: MLRPLRKSVLASCRHCFKVCGGLPQKQLPLFSPLLLRARYSSTDSSTKRSNKSDKIDAPGFKKIFLVAIIGTVIFVKTVQSLDKNKPKTTLSEEEFENVVKGLKRRVAIFPQGEVDIKFSLSPSIEETRKVLQKSQGDDINELQFVDPVKVIDYYRTLRDDRYEALLNEYYKKYGCDTYAYNLPTGMLVMLLGRYFKENFKAGDKLVVVNFPHSIADATRFENEVSIVSKIFVPRKLSGSDVCKYYETVGKADII
What are the official names of this protein?
Altered inheritance of mitochondria protein 36, mitochondrial, Found in mitochondria protein 39.
What is the protein family that this protein belongs to?
Belongs to the AIM36 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: KCY_XYLFA
Sequence: MADLVPVLTIDGPSGVGKGTVSKIVAARLGWHYLDSGALYRAVAVAADWTAVDVSDTTALVKCAFDTCVNFAKCADGEMRVLVNAIDATDVLRMETTGVLASTIAAISEVRAALKERQQMFRRTPGLVADGRDMGTVIFPDAQYKVFLTAKAEERAQRRYKQLMKKGVSVMLGALLEEIRARDARDACRSVAPLKPADDALLIDSTCMEVDEVVAQVLALVTD
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_PSESM
Sequence: MAFLALGINHKTASVDVRERVAFTPEQLVDALQQLCHLTESREAAILSTCNRSELYIEHEHLGADSILAWLANYHHLSLEELRASAYVHEDDAAVRHMMRVASGLDSLVLGEPQILGQMKSAYAVAREAGTVGPLLGRLFQATFSAAKQVRTDTAIGENPVSVAFAAVSLAKQIFSDLQRSQALLIGAGETITLVARHLHDLGVKRIVVANRTLERASILAAEFGAHAVLLSDIPAELVNSDIVISSTASQLPILGKGAVESALKLRKHKPIFMVDIAVPRDIEPEVGELDDVYLYSVDDLHEVVAENLKSRQGAALAAEQLVSVGAEDFMSRLRELAAVDVLRAYRQQSERLRDEELSKAQRMLANGSNAEDVLIQLARGLTNKLLHAPSVQLKKLSAEGRVDALAMAQELFALGEGSTDKTPQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: APGM_METBU
Sequence: MKYIILIGDGMADHPLEELGGMTALQKANTPNMDQMTKNGLAGLAINVPEGYSPGSDVANMSVMGYDPALYYSGRAPLEAASMGIPLEVNDVAFRCNLITIRDGLITDHSAGHITSEEARELIEAVDAELGSEGLKFYPGISYRHLLVASNGLGANADCTPPHDVIDGEINDHMPRGDGSDVLGKLIEGSIPILEGHPINEKRISEGKNPGNSVWFWGQGYAPSFRTFEDLYGLTGSVISAVDLIMGLGIYAGLDVIEVPGATGYLDTNYVGKAEFAMASLKDKDFVVVHVEAPDEAGHMGDIEAKLQAIEDFDEKVVGTVLRAARESDEDYTIVVLPDHPTPIALRTHTSEPVPFVMYSTLEDEVDDVETFDEDAMKKGSLGIVRGCDLVQLMMERAKQA
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, aPGAM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
Protein: NU2M_CROHI
Sequence: MNPMIFIILLATIMLGSSIVMMSSHWFMTWLGFEMNMMAIVPVLMKKYSPRSMEAATKYFLTQATASMILMLAIIINLMYSGQWTIANMENHTASMLITIALVMKLGLAPFHFWVPEVTQGIPLSSGLILLTWQKIAPLSLLYQIHSSINMELFLTMSLLSIVIGGWGGLNQTQLRKIMAYSSIGHMGWMMAIMNYNPNLSFLNLLVYILMTSSMFALLIFSSTTSTLSLSLAWNKTPIIATMSLIILLSLGGLPPLTGFMPKWMIIQELTKNNSTILPTLMAISALLNLFFYIRLTYSTALTMFPTMNNMKLTWQFQNTNILPMILPLITISTLALPLTPLFLMLN
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RAB35_MOUSE
Sequence: MARDYDHLFKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQIWDTAGQERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNCDDVCRILVGNKNDDPERKVVETEDAYKFAGQMGIQLFETSAKENVNVEEMFNCITELVLRAKKDNLAKQQQQQQNDVVKLTKNSKRKKRCC
What is the function of this protein?
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes.  Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion.  That Rab is involved in the process of endocytosis and is an essential rate-limiting regulator of the fast recycling pathway back to the plasma membrane.  During cytokinesis, required for the postfurrowing terminal steps, namely for intercellular bridge stability and abscission, possibly by controlling phosphatidylinositol 4,5-bis phosphate (PIP2) and SEPT2 localization at the intercellular bridge.  May indirectly regulate neurite outgrowth.  Together with TBC1D13 may be involved in regulation of insulin-induced glucose transporter SLC2A4/GLUT4 translocation to the plasma membrane in adipocytes.
What are the official names of this protein?
Ras-related protein Rab-35.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Membrane, clathrin-coated pit. Cytoplasmic vesicle, clathrin-coated vesicle. Endosome. Melanosome. Note=Present on sorting endosomes and recycling endosome tubules. Tends to be enriched in PIP2-positive cell membrane domains. During mitosis, associated with the plasma membrane and present at the ingressing furrow during early cytokinesis as well as at the intercellular bridge later during cytokinesis. Identified in stage I to stage IV melanosomes.
Protein: RL28_MARSD
Sequence: MSQVCDICGKGPQTGNNVSHAHNKTKRRFMPNLQKVRTQLPSGEVKSIKACTRCIRSGAVVKPVAKKAVS
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: RK22_ORYSA
Sequence: MTSFKLVKYTPRIKKKKSGLRKLARKVPTDRLLKFERVFKAQKRIHMSVFKVQRVLDEIRWRYYEETVMILNLMPYRASYPILKLVYSAAANATHYRDFDKANLFITKAEVSRSTIMNKFRPRARGRSSPIKKTMCHITIVLNIVKKSK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.