PharMolix/UniProtQA huggingface dataset:
Protein: ZCHC9_HUMAN
Sequence: MTRWARVSTTYNKRPLPATSWEDMKKGSFEGTSQNLPKRKQLEANRLSLKNDAPQAKHKKNKKKKEYLNEDVNGFMEYLRQNSQMVHNGQIIATDSEEVREEIAVALKKDSRREGRRLKRQAAKKNAMVCFHCRKPGHGIADCPAALENQDMGTGICYRCGSTEHEITKCKAKVDPALGEFPFAKCFVCGEMGHLSRSCPDNPKGLYADGGGCKLCGSVEHLKKDCPESQNSERMVTVGRWAKGMSADYEEILDVPKPQKPKTKIPKVVNF
What is the function of this protein?
May down-regulate transcription mediated by NF-kappa-B and the serum response element.
What are the official names of this protein?
Zinc finger CCHC domain-containing protein 9.
Protein: RL24_PAGMA
Sequence: MKVELCSFSGYKIYPGHGRRYARIDGKVFQFLNAKCESAFLAKRNPRQINWTVLYRRKHKKGQSEEVAKKRTRRAVKFQRAITGASLAEIMAKRNQKPEVRKAQREQAIRAAKEAKKAKQAAKKPAAPSAKASTKTAQKPKIAKPMKISAPRVGGKR
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL24 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_FRAAA
Sequence: MIDDTLLDAEEKMEKAVSVAKEDFANIRTGRITPAVFSKIVVDYYGAPTPVQQLASFHIPEPRMVIITPYDKSSLASIEKAVRDSDLGVNPSNDGTIIRIVFPELSEQRRRDLVKVARSKAEEARVSIRNVRRHAKDGIDRIVRDGDAGEDEGRRAEKDLDEATHRYVGQVDELLRLKEADLLSV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOC2B_PONAB
Sequence: MSSLEISSSCFNLETKLPLSPPLVEDSAFEPSRKDMDEVEEKSKDVINFTAEKLSVDEVSQLVISPLCGAISLFVGTTRNNFEGKKVISLEYEAYLPMAENEVRKICSDIRQKWPVKHIAVFHRLGHRAASLEAVSYAIDTLKAKVPIWKKEIYEESSSWKGNKECFWASNN
What is the function of this protein?
Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin.  Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
What are the official names of this protein?
Molybdopterin synthase catalytic subunit, Molybdenum cofactor synthesis protein 2 large subunit, Molybdenum cofactor synthesis protein 2B, MOCS2B.
What is the protein family that this protein belongs to?
Belongs to the MoaE family. MOCS2B subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: HBA_NOTEU
Sequence: MVLSAADKGHVKGIWGKVGGHAGEYAAEGLERTFHSFPTTKTYFPHFDLSHGSAQIQAHGKKIADALGQAVEHIDDLPGTLSKLSDLHAHKLRVDPVNFKLLSHCLLVTFAAHLGDAFTPEVHASLDKFLAAVSTVLTSKYR
What is the function of this protein?
Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1.  Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.
What are the official names of this protein?
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: AROQ1_COREF
Sequence: MTGRILLLNGPNLNMLGLREPEIYGHATLDDVVELVRARAEHHGLEVDAVQSNHEGDLIDALHRARGTHLGCVLNPGGLTHTSVSLLDAVKASELPTVEVHISNPHARESFRHHSYISPVAAAVIAGAGVDGYGFAVDILANNHLQRTASQ
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase 1, 3-dehydroquinase 1, Type II DHQase 1.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: PGSA_YERE8
Sequence: MQLNIPTWLTLFRVVLIPFFVLAFYLPFVWAPMVCAIIFVFAAATDWFDGFLARRWKQTTRFGAFLDPVADKVMVAIALVLVAEHYHVWWITLPAATMIAREIIISSLREWMAEIGKRSSVAVSWIGKVKTTAQMGSLVGLLWRPDHNIELASFVLLYIAAVLTFWSMFQYLNAAWKDLLEP
What is the function of this protein?
This protein catalyzes the committed step to the synthesis of the acidic phospholipids.
What are the official names of this protein?
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, Phosphatidylglycerophosphate synthase, PGP synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IL27A_MOUSE
Sequence: MGQVTGDLGWRLSLLLLPLLLVQAGSWGFPTDPLSLQELRREFTVSLYLARKLLSEVQGYVHSFAESRLPGVNLDLLPLGYHLPNVSLTFQAWHHLSDSERLCFLATTLRPFPAMLGGLGTQGTWTSSEREQLWAMRLDLRDLHRHLRFQVLAAGFKCSKEEEDKEEEEEEEEEEKKLPLGALGGPNQVSSQVSWPQLLYTYQLLHSLELVLSRAVRDLLLLSLPRRPGSAWDS
What is the function of this protein?
Associates with EBI3 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity.  IL-27 has pro- and anti-inflammatory properties, that can regulate T-helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells.  Among its target cells are CD4 T-helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17).  It drives rapid clonal expansion of naive but not memory CD4 T-cells.  It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR which appears to be required but not sufficient for IL-27-mediated signal transduction.  IL-27 potentiate the early phase of TH1 response and suppress TH2 and TH17 differentiation.  It induces the differentiation of TH1 cells via two distinct pathways, p38 MAPK/TBX21- and ICAM1/ITGAL/ERK-dependent pathways.  It also induces STAT1, STAT3, STAT4 and STAT5 phosphorylation and activates TBX21/T-Bet via STAT1 with resulting IL12RB2 up-regulation, an event crucial to TH1 cell commitment.  It suppresses the expression of GATA3, the inhibitor TH1 cells development.  In CD8 T-cells, it activates STATs as well as GZMB.  IL-27 reveals to be a potent inhibitor of TH17 cell development and of IL-17 production.  Indeed IL27 alone is also able to inhibit the production of IL17 by CD4 and CD8 T-cells.  While IL-27 suppressed the development of pro-inflammatory Th17 cells via STAT1, it inhibits the development of anti-inflammatory inducible regulatory T-cells, iTreg, independently of STAT1.  IL-27 has also an effect on cytokine production, it suppresses pro-inflammatory cytokine production such as IL2, IL4, IL5 and IL6 and activates suppressors of cytokine signaling such as SOCS1 and SOCS3.  Apart from suppression of cytokine production, IL-27 also antagonizes the effects of some cytokines such as IL6 through direct effects on T-cells.  Another important role of IL-27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines such as IP-10/CXCL10 and MIG/CXCL9.
What are the official names of this protein?
Interleukin-27 subunit alpha, IL-27 subunit alpha, IL-27-A, IL27-A, p28.
What is the protein family that this protein belongs to?
Belongs to the IL-6 superfamily.
What are the subcellular locations of this protein?
Secreted. Note=Poorly secreted without coexpression of EBI3.
Protein: TUT3_TRYBB
Sequence: MIFFFKKRYHVFLKAPSIRLMPCSFFFFRSFIKVIFIIRCIFFSSLSGDSCPTQRSRSTLACMFTSVPVAPTVVPGVVYSSGVHEEWKEAEQKLLDGCLIHSEGDGATKQIKEKLTSRNSQSVRCDLCAKMIESRDEEQIQEHFQVHHAALSLWCREILASKDNLLHYGCIPSGHIVSCGNFVLESAATLDMGRKTFDVIERAFSQMSQVISCFVRNLVLFPFGSCVSCGCWDGVSDADFTAIGLQDMKKGKWPPEDEKKVILRLTAALRKAGFFFGELEPLVRTRVPVVRRVQKVRVPLRSHGEHDTYSVVWSNSKEFSSPPRMLVEAAISSTVERKDSDTVTFHFKDSLKAVKFFCNSAMCGPRDMEVSWKTGSQLPEMFSLDFDLSCRAQGVRNSLFLRKYFQQDPFVRTGYLFLKKWSKLYGINNAKNGYLTSYAMSILWVHFLLENGLVKFVRPADVEPIPDLSQQKMSYLPLLRDDGDGGERPSDVLKSPELTMLRGALGGLIPLFFLYYTRIRWDKVVVTLRVPGGGPPVTPDSLGWVEANEVKCGPLRDRVWYRLCIDDPYEDNFNLGRHLSPDKASFVKVQFMRALASIVAGRPQQLLVDEQKFAEETMPAYVTRLSVQGELRNLRPVTVSALRQLLIDSAGADCVAIYEASHNWETLLDMASTLNNKSKEGDDDAEGVTNNQEGEPPDHVESCEAPRRHLLCSKMHSIDDALLVAGPLGVSDANIPAGLLGVYFLARGRAFRTAEDRDNFLMHAEAVSAARARGCTTREEILERVADAIPSIVRNGTLLDDLLVSGSEENITVQSPVVVETRCAETVQRKKSKGSKKRKNAVRRGNHAGQGTCSECGASGTDLWEASDKSADDGLYCGACWKAYNCQKN
What is the function of this protein?
Terminal uridylyltransferase which catalyzes the addition of Us to the 3'-hydroxyl group of single-stranded RNAs (PubMed:15304317).  Does not mediate RNA-independent UTP polymerization (PubMed:15304317).
What are the official names of this protein?
Terminal uridylyltransferase 3, TUTase 3, 3' terminal uridylyl transferase, RNA editing 3' terminal uridylyltransferase 3.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B-like family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOI_BORBR
Sequence: MEAIKDFFGSLLLTELFKGLRLTGKYFFKRKVTLRYPMEKTPTSARFRGLHALRRYPNGEERCIACKLCEAVCPALAITIESEQRDDGTRRTTRYDIDLTKCIFCGFCEESCPVDSIVETHIHEYHGEKRGDLYFTKDMLLAVGDRYEAEIARRRAEDAPYR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ALL2_ARTVU
Sequence: XETYGEPGNTPDDYVHAHNNIRRVLGMXPKXQGAIDGSSXVQLXLDEXLDYDYNXNKXIKPPGNVVGQLPY
What are the official names of this protein?
Allergen Art v 2, Allergen Ag7, Allergen Art v II.
Protein: UBTD1_MOUSE
Sequence: MGNCVGRQRRERPAAPGHPRKRAGRNEPLKKERLKWKSDYPMTDGQLRSKRDEFWDTAPAFEGRKEIWDALKAAAYAAEANDHELAQAILDGASITLPHGTLCECYDELGNRYQLPIYCLSPPVNLLLEHTEEESLEPPEPTPSVRREFPLKVRLSTGKDVRLNASLPDTVGQLKRQLHSQEGIEPSWQRWFFSGKLLTDRTRLQETKIQKDFVIQVIINQPPPPQD
What is the function of this protein?
May be involved in the regulation of cellular senescence through a positive feedback loop with TP53.  Is a TP53 downstream target gene that increases the stability of TP53 protein by promoting the ubiquitination and degradation of MDM2.
What are the official names of this protein?
Ubiquitin domain-containing protein 1.
Protein: FPG_STRPN
Sequence: MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRELPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGGTLVYEDVRKFGTMELLVPDLLDVYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSHLLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGSTIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: SDHF3_HUMAN
Sequence: MPGRHVSRVRALYKRVLQLHRVLPPDLKSLGDQYVKDEFRRHKTVGSDEAQRFLQEWEVYATALLQQANENRQNSTGKACFGTFLPEEKLNDFRDEQIGQLQELMQEATKPNRQFSISESMKPKF
What is the function of this protein?
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants.  May act together with SDHAF1.
What are the official names of this protein?
Succinate dehydrogenase assembly factor 3, mitochondrial, SDH assembly factor 3, SDHAF3.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family. SDHAF3 subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: TYE7_YEAST
Sequence: MNSILDRNVRSSETTLIKPESEFDNWLSDENDGASHINVNKDSSSVLSASSSTWFEPLENIISSASSSSIGSPIEDQFISSNNEESALFPTDQFFSNPSSYSHSPEVSSSIKREEDDNALSLADFEPASLQLMPNMINTDNNDDSTPLKNEIELNDSFIKTNLDAKETKKRAPRKRLTPFQKQAHNKIEKRYRININTKIARLQQIIPWVASEQTAFEVGDSVKKQDEDGAETAATTPLPSAAATSTKLNKSMILEKAVDYILYLQNNERLYEMEVQRLKSEIDTLKQDQK
What is the function of this protein?
Transcriptional activator of glycolytic gene expression, such as enolase genes (ENO1 and ENO2), glyceraldehyde-3-phosphate dehydrogenase gene (TDH), phosphoglycerate kinase (PGK1), phosphoglycerate mutase (PGM1), pyruvate kinase (PYK1) and triosephosphate isomerase (TPI1) genes.  Binds DNA on E-box motifs: 5'-CANNTG-3'.
What are the official names of this protein?
Serine-rich protein TYE7, Basic-helix-loop-helix protein SGC1.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRMY_HALMA
Sequence: MRQFVIIGHDAPTTPEFSLDDLAGAAGRLDVLCRCVTSAFFLSHAIREDVRVHLILGDEYTVTFEGSDLRRLNPDERSTAALIRKALEEREEAIGHIPVETSPGVSLTRRGFEGTLDDVARRGTVVQLHEDGDPIVGVAPPSDPVFVLSDHHDFRDEEAALLADRADERVSLGPKALHADHSITVAHNYLDTAGFERY
What is the function of this protein?
Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs.
What are the official names of this protein?
tRNA (pseudouridine(54)-N(1))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. TrmY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METXA_THEFY
Sequence: MSHDTTPPLPATGAWREGDPPGDRRWVELSEPLPLETGGELPGVRLAYETWGSLNEDRSNAVLVLHALTGDSHVVGPEGPGHPSPGWWEGIIGPGLALDTDRYFVVAPNVLGGCQGSTGPSSTAPDGRPWGSRFPRITIRDTVRAEFALLREFGIHSWAAVLGGSMGGMRALEWAATYPERVRRLLLLASPAASSAQQIAWAAPQLHAIRSDPYWHGGDYYDRPGPGPVTGMGIARRIAHITYRGATEFDERFGRNPQDGEDPMAGGRFAVESYLDHHAVKLARRFDAGSYVVLTQAMNTHDVGRGRGGVAQALRRVTARTMVAGVSSDFLYPLAQQQELADGIPGADEVRVIESASGHDGFLTEINQVSVLIKELLAQ
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MGMT_DEBHA
Sequence: MKNIYLLYSIIDVSYTKALIVTNTHGSLYYASLGDKPEVLIVTMKKDFARFKNYVLQPIVGKANSEVSETLEKFRLMAEDPRLINTMHKQIPYEFIFGTELQRKVWNQLMNTNASETVCYSQMASNLGMPKSSRVVGAACGANKIALFVPCHRALTKSGQISGYRWGVPLKQRLLKLEQKPLQKESSLKEK
What is the function of this protein?
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA.  Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme.  This is a suicide reaction: the enzyme is irreversibly inactivated.
What are the official names of this protein?
Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNA methyltransferase, MGMT, DNA repair MTase, O-6-methylguanine-DNA-alkyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MGMT family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SAS10_YEAST
Sequence: MVRKGSNRTKTSEVGDEINPYGLNEVDDFASKREKVLLGQSTFGDSNKDDDHSLLEDEDEEEVLAMDEDDESIDEREDEEEEEEEELDGAAAYKKIFGRNLETDQLPEEDEENGMLDNENAWGSTKGEYYGADDLDDDEAAKEIEKEALRQQKKHLEELNMNDYLDEEEEEEWVKSAKEFDMGEFKNSTKQADTKTSITDILNMDDEARDNYLRTMFPEFAPLSKEFTELAPKFDELKKSEENEFNKLKLIALGSYLGTISCYYSILLHELHNNEDFTSMKGHPVMEKILTTKEIWRQASELPSSFDVNEGDGSESEETANIEAFNEKKLNELQNSEDSDAEDGGKQKQEIDEEERESDEEEEEEDVDIDDFEEYVAQSRLHSKPKTSSMPEADDFIESEIADVDAQDKKARRRTLRFYTSKIDQQENKKTDRFKGDDDIPYKERLFERQQRLLDEARKRGMHDNNGADLDDKDYGSEDEAVSRSINTQGENDYYQQVQRGKQDKKISRKEAHKNAVIAAREGKLAELAENVSGDGKRAINYQILKNKGLTPKRNKDNRNSRVKKRKKYQKAQKKLKSVRAVYSGGQSGVYEGEKTGIKKGLTRSVKFKN
What is the function of this protein?
Primarily required at the G2/M phase.  Essential for viability: involved in nucleolar processing of pre-18S ribosomal RNA as part of the ribosomal small subunit (SSU) processome.
What are the official names of this protein?
Something about silencing protein 10, U three protein 3, U3 small nucleolar RNA-associated protein 3, U3 snoRNA-associated protein 11.
What is the protein family that this protein belongs to?
Belongs to the SAS10 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RUVC_CYAP4
Sequence: MVKRILGLDPGLATLGFGSITVQPDESLQVLDFGVIKTAAGEEIGSRLLTIYEDLHTLLQHFQPDLVAIEKFFFYRMSNTILVAQARGVILLVLAQHHLALMEFTPAQVKQTLTGHGNADKQEVQLAVQRELKLESLPRPDDAADALALALTASFQR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: MNHB1_STAAS
Sequence: MNRQQNDLILQFAAVIIFFMVMVFGFSLFLAGHYTPGGGFVGGLLFASSLVIITIAFDIETMRKIFPLDFKILIGIGLVFCIATPIASWFLGKNFFTHVTFDIPLFILEPVHMTTAVFFDFGVLCAVVGTVMTIIISIGENE
What is the function of this protein?
Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.
What are the official names of this protein?
Na(+)/H(+) antiporter subunit B1, Mnh complex subunit B1.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MYB17_ARATH
Sequence: MGRTPCCDKIGLKKGPWTPEEDEVLVAHIKKNGHGSWRTLPKLAGLLRCGKSCRLRWTNYLRPDIKRGPFTADEEKLVIQLHAILGNRWAAIAAQLPGRTDNEIKNLWNTHLKKRLLSMGLDPRTHEPLPSYGLAKQAPSSPTTRHMAQWESARVEAEARLSRESMLFSPSFYSGVVKTECDHFLRIWNSEIGEAFRNLAPLDESTITSQSPCSRATSTSSALLKSSTNSWGGKEVTVAIHGSDYSPYSNDLEDDSTDSALQLLLDFPISDDDMSFLEENIDSYSQAPPIGLVSMVSKF
What is the function of this protein?
Transcription factor that may play a role in flower development by repressing ANT (PubMed:19232308).  Regulates the transition of meristem identity from vegetative growth to flowering.  Acts downstream of LFY and upstream of AP1.  Directly activates AP1 to promote floral fate.  Together with LFY and AP1 may constitute a regulatory network that contributes to an abrupt and robust meristem identity transition (PubMed:21750030).
What are the official names of this protein?
Transcription factor MYB17, Myb-related protein 17, AtMYB17, Protein LATE MERISTEM IDENTITY 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL15_BACCZ
Sequence: MKLHELKPAEGSRKVRNRVGRGIGSGNGKTAGKGHKGQNARSGGGVRLGFEGGQTPLFRRLPKRGFTNINRKEFAIVNLSTLNRFEDGTEVTPELLLETGVISKLNDGVKILASGAVEKKLTVKAHKFSSSAKEAIEAAGGSVEVI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: 022L_IIV3
Sequence: MSFVHKLPTFYTAGVGAIIGGLSLRFNGAKFLSDWYINKYNDSVPAWSLQTCHWAGIALYCVGWVTLASVIYLKHRDNSILKGSILSCIVISAVWSILEYNQDMFVSNPKLPLISCAMLVSSLAALVALKYHIKDIFTILGAAIIIILAEYVVLPYQRQYNIVDGIGLPLLLLGFFILYQVFSVPNPSTPTGVMVPKPEDEWDIEMAPLNHRDRQVPESELENVK
What are the official names of this protein?
Transmembrane protein 022L.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: SSB2_STAAM
Sequence: MLNRTVLVGRLTKDPELRSTPNGVNVGTFTLAVNRTFTNAQGEREADFINVVVFKKQAENVKNYLSKGSLAGVDGRLQTRNYENKDGQRVFVTEVVADSVQFLEPKNNNQQQNNNYQQQRQTQTGNNPFDNNADSIEDLPF
What are the official names of this protein?
Single-stranded DNA-binding protein 2, SSB 2.
Protein: HS2ST_CHICK
Sequence: MGLLRIMLPPKLQLLAVLVFGVAVLFLENQIQKLEESRGKLERAIARHEVREIEQRHTADGPRQEVALDEEDDVVIIYNRVPKTASTSFTNIAYDLCAKNRYHVLHINTTKNNPVMSLQDQVRFVKNVTSWKEMKPGFYHGHVSYLDFAKFGVKKKPIYINVIRDPIERLVSYYYFLRFGDDYRPGLRRRKQGDKKTFDECVAAGGSDCAPEKLWLQIPFFCGHSSECWNVGSRWALEQAKYNLINEYFLVGVTEELEDFIMLLEAALPRFFRGATELYRTGKKSHLRKTTEKKLPTKETIAKLQQSEIWKMENEFYEFALEQFQFVRAHAVREKDGELYILAQNFFYEKIYPKSN
What is the function of this protein?
Catalyzes the transfer of sulfate to the C2-position of selected hexuronic acid residues within the maturing heparan sulfate (HS).  2-O-sulfation within HS, particularly of iduronate residues, is essential for HS to participate in a variety of high-affinity ligand-binding interactions and signaling processes.
What are the official names of this protein?
Heparan sulfate 2-O-sulfotransferase 1, cHS2ST.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 3 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: RS15_BRADU
Sequence: MSIAAERKAEVIKTNATKAGDTGSPEVQVAILSERINNLTSHFKTHVKDNHSRRGLLKLVSTRRSLLDYLKKRDEARYKALLEKHNIRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: PMRA_LACLA
Sequence: MNRTKTVNWKRNLFITWIGCFFVGSSFSLVMPFLPLYIQGLGVSGGNVELYSGLAFSLPALASGLVAPIWGRLADEHGRKVMMVRASIVMTLTMGGIAFAPNVWWLLGLRLLMGFFSGYIPNSTAMIASQAPKDKSGYALGTLATAMVSGTLIGPSLGGLLAEWFGMANVFLIVGALLALATLLTIFFVHENFEPIAKGEMLSSKEIINKVSNKQILFGLLVTTFIIQITSQSIEPFVTLYIKTLTTSTNNLMFISGLIVSAVGLSAMLSSSFLGRLGDKYGSHRLILIGLVFTFIIYLPMAFVQSPLQLGILRFLLGFGTGALTPSVNSLLSKITPKEGVSRIFAYAQMCSNLGMVTGPLVGSAIAGYISYRAAIVGTSLFVIVNIIWSFINFRKYLRKRSIME
What is the function of this protein?
Efflux pump for various substrates.
What are the official names of this protein?
Multi-drug resistance efflux pump PmrA homolog.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DXR_NAUPA
Sequence: MVVLGSTGSIGVNTLEIARRYDIEIEGLVAGNNYEVLNAQIKEFKPKYVVVKDLKTAEKIDFPNVKYGEEAVLDMIEKSKSDLIVNALVGDAGLRPTLKAQECGKKIALANKESLVNAGKFIDTSKITPIDSEHFGLWYLLIEKCRVKSEKCNVKKLYITASGGALRDWSLEDIKKATLKDVLKHPNWSMGVKITIDSATMVNKLFELLEAKWLFDTDKIDAFIETKSIIHALVEWQDGSTTAHISKTDMKLPIAFAVLDEVNDEILSPVNLLEVGGLEFRKIEVEKYPVWEIKDLLLIKPDLGVVVNTANEFAIEKFLEERISFIDISGIILKAVQKFENVNINGIDDVFEIKNEVRKWCESNFV
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.