PharMolix/UniProtQA huggingface dataset:
Protein: GLO2_LEGPH
Sequence: MTILPISAFSDNYIWTFIDKIAGVLDCVDPGEAAPIIRFAQSNQLTLRTILLTHHHYDHIGGVDSLIKQWPSCKVYGPIDERINNVTHPIKQGQSVQVGSLHFHILFNPGHTSTHISYYEPQQGWLFCGDTLFSAGCGRVFDGTIEELHESLLLFKKLPRNTKVFCAHEYTFQNLKFAHTVEPCNSSVINYMQQILKQPSSCTLPSNIDLELSINPFLRTDKEQVKQYALSHGANSSDSLDVFKVLRNQKNSFK
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: GDE1_HUMAN
Sequence: MWLWEDQGGLLGPFSFLLLVLLLVTRSPVNACLLTGSLFVLLRVFSFEPVPSCRALQVLKPRDRISAIAHRGGSHDAPENTLAAIRQAAKNGATGVELDIEFTSDGIPVLMHDNTVDRTTDGTGRLCDLTFEQIRKLNPAANHRLRNDFPDEKIPTLREAVAECLNHNLTIFFDVKGHAHKATEALKKMYMEFPQLYNNSVVCSFLPEVIYKMRQTDRDVITALTHRPWSLSHTGDGKPRYDTFWKHFIFVMMDILLDWSMHNILWYLCGISAFLMQKDFVSPAYLKKWSAKGIQVVGWTVNTFDEKSYYESHLGSSYITDSMVEDCEPHF
What is the function of this protein?
Hydrolyzes the phosphodiester bond of glycerophosphodiesters such as glycerophosphoinositol (GroPIns) and glycerophosphoethanolamine (GroPEth), to yield a glycerol phosphate and an alcohol (By similarity).  Hydrolyzes glycerophospho-N-acylethanolamines to N-acylethanolamines in the brain and participates in bioactive N-acylethanolamine biosynthesis such as anandamide (an endocannabinoid), N-palmitoylethanolamine (an anti-inflammatory), and N-oleoylethanolamine (an anorexic).  In addition, has a lysophospholipase D activity by hydrolyzing N-acyl-lysoplasmenylethanolamine (N-acyl-lysoPlsEt) to N-acylethanolamine.  However lysophospholipase D activity is lower than glycerophosphodiester phosphodiesterase activity (By similarity).  Has little or no activity towards glycerophosphocholine (By similarity).
What are the official names of this protein?
Glycerophosphodiester phosphodiesterase 1, Glycerophosphoinositol glycerophosphodiesterase GDE1, Lysophospholipase D GDE1, Membrane-interacting protein of RGS16, RGS16-interacting membrane protein.
What is the protein family that this protein belongs to?
Belongs to the glycerophosphoryl diester phosphodiesterase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Perinuclear vesicles and cell membrane.
Protein: ZBT18_HUMAN
Sequence: MEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHLFYKDQLDKRDIVHLNSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVKVCKKKLKEKATTEADSTKKEEDASSCSDKVESLSDGSSHIAGDLPSDEDEGEDEKLNILPSKRDLAAEPGNMWMRLPSDSAGIPQAGGEAEPHATAAGKTVASPCSSTESLSQRSVTSVRDSADVDCVLDLSVKSSLSGVENLNSSYFSSQDVLRSNLVQVKVEKEASCDESDVGTNDYDMEHSTVKESVSTNNRVQYEPAHLAPLREDSVLRELDREDKASDDEMMTPESERVQVEGGMESSLLPYVSNILSPAGQIFMCPLCNKVFPSPHILQIHLSTHFREQDGIRSKPAADVNVPTCSLCGKTFSCMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGDLYRHIRKFHCELVNSLSVKSEALSLPTVRDWTLEDSSQELWK
What is the function of this protein?
Transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain development.  Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2 inhibitors of skeletal myogenesis.  Also involved in controlling cell division of progenitor cells and regulating the survival of postmitotic cortical neurons.  Specifically binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes.  May also play a role in the organization of chromosomes in the nucleus.
What are the official names of this protein?
Zinc finger and BTB domain-containing protein 18, 58 kDa repressor protein, Transcriptional repressor RP58, Translin-associated zinc finger protein 1, TAZ-1, Zinc finger protein 238, Zinc finger protein C2H2-171.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family. ZBTB18 subfamily.
What are the subcellular locations of this protein?
Nucleus. Note=Associates with condensed chromatin.
Protein: ATPA_ACOAM
Sequence: MATLRADEISNIIRERIEQYTREVKVVNTGTVLQVGDGIARIHGLDEVMAGELVEFEEGTIGIALNLESNNVGVVLMGDGLTIQEGSSVKATGRIAQIPVSEAYLGRVVNALAKPIDGRGEIAASEFRLIESPAPGIISRRSVYEPLQTGLIAIDSMIPVGRGQRELIIGDRQTGKTAVATDTILNQKGQNVICVYVAIGQKASSVAQVVTNFQERGAMEYTIVVAETADSPATLQYLAPYTGAALAEYFMYRERHTSIIYDDLSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKSSSRLGEGSMTALPIVETQSGDVSAYIPTNVISITDGQIFLSADLFNAGIRPAINVGISVSRVGSAAQIKAMKQVAGKSKLELAQFAELEAFAQFASDLDKATQNQLARGKRLRELLKQSQSEPLAVDEQVVTIYTGTNGYLDTLEIGQVKEFLVKLRTYLKKNKPQFQEIISSTKTFTEEAEALLKEAIQEQLELFLLQEQT
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, chloroplastic, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: ADA28_MOUSE
Sequence: MQQWSLLVVSFLLSPVPVSAIKELPKAKKYEVVYPIRLHPLRKRETQEPEPKETFETELRYKMTVNGKVAVLYLKKNNKLLAPDYSETYYNSSGNKVTTSPQIMDSCYYQGHIVNEKVSAASISTCQGLRGYISQGDEKYFIEPLSSENLDEQAHALFKDDSNEDQEKSNCGVDDALWLQGLHQDVALPATRLIKLNDGMVQEPKKYIEYYVVLDNGEFKKYNKNLAEIRKIVLEMANYINMLYNKLDAHVALVGVEIWTDGDKIKITPDANTTLENFSKWRGNDLLKRKHHDIAQLISSTDFSGSTVGLAFMSSMCSPYHSVGIVQDHSNYHLRVAGTMAHEMGHNLGMIHDYLSCKCPSEVCVMEQSLRFHMPTDFSSCSRVNYKQFLEEKLSHCLFNSPLPSDIISTPVCGNQLLEMNEDCDCGTPKECTNKCCDARTCKIKAGFQCALGECCEKCQLKKPGVVCRAAKDECDLPEVCDGKSSHCPGDRFRVNGSPCQNGHGYCLKGKCPTLQQQCMDMWGPGTKVANTSCYKQNEGGTKYGYCHVENGTHMPCKAKDAMCGKLFCEGGSGDLPWKGLTISFLTCKLFDPEDTSQGVDMVANGTKCGTNKVCINAECVDMEKTYKSANCSSKCKGHAVCDHELQCQCKEGWAPPDCENSATVFHFSIVVGVLFPLAVIFVVVAIVIQRQSARRKQRRVQRLPSTKDAKLHNQKCRPQKVKDVQPQEMSQMKKLHVSDLPSEEPEPPPDVLITKPNFPPPPIPVSLTGRAKVPFVKTPHPFSQQIGRVYLK
What is the function of this protein?
May play a role in organogenesis and organ-specific functions such as thymic T-cell development.
What are the official names of this protein?
Disintegrin and metalloproteinase domain-containing protein 28, ADAM 28, Thymic epithelial cell-ADAM, TECADAM.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: GTHB1_ANGJA
Sequence: MHLAVTALCLTLAPVLARASTSCGLANISISVENEECGGCITFNTTACAGLCFTQDSVYKSSLKSYPQQACNFRDVVYETVHLPGCPSGMDLHFTYPVALSCECSKCNTDSTDCGPLNTEVSGCLTH
What is the function of this protein?
Involved in gametogenesis and steroidogenesis.
What are the official names of this protein?
Gonadotropin subunit beta-1, GTH-I-beta, Gonadotropin beta-I chain.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: MYOD1_CHICK
Sequence: MDLLGPMEMTEGSLCSFTAADDFYDDPCFNTSDMHFFEDLDPRLVHVGGLLKPEEHPHTRAPPREPTEEEHVRAPSGHHQAGRCLLWACKACKRKTTNADRRKAATMRERRRLSKVNEAFETLKRCTSTNPNQRLPKVEILRNAIRYIESLQALLREQEDAYYPVLEHYSGESDASSPRSNCSDGMMEYSGPPCSSRRRNSYDSSYYTESPNDPKHGKSSVVSSLDCLSSIVERISTDNSTCPILPPAEAVAEGSPCSPQEGGNLSDSGAQIPSPTNCTPLPQESSSSSSSNPIYQVL
What is the function of this protein?
Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation.  Induces fibroblasts to differentiate into myoblasts.  Interacts with and is inhibited by the twist protein.  This interaction probably involves the basic domains of both proteins (By similarity).
What are the official names of this protein?
Myoblast determination protein 1 homolog, MYOD1 homolog.
What are the subcellular locations of this protein?
Nucleus.
Protein: COPE_DICDI
Sequence: MSDDILFESKNYFYLGNYQSTINEINKKSRQIIEKSLKAESDYFLYRCYIAQGNYDLVLQETKNNRGSGEDPTIAGLQLLASYLSKPDENREGTLITITQWISDGVVKFNYHLQVIIATIYFNEQLYDEALQILNNCDHIEGLSMLIQIFLKIDRLDLAQKAYDTMKKIIDPDATPALLSLAWINIYNGEEKLKSALSSFEEMAERYGPTPLLLNGQAVCAIGMKRFEKAESLLLESIEKNPKNSDTLANLINCYINMKKPNEIIQRFINQLKTLSPKHDWTSAVNEAEALFEVSKSRFN
What is the function of this protein?
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.  The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).
What are the official names of this protein?
Coatomer subunit epsilon, Epsilon-coat protein, Epsilon-COP.
What is the protein family that this protein belongs to?
Belongs to the COPE family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: BEX5_HUMAN
Sequence: MENVPKENKVVEKAPVQNEAPALGGGEYQEPGGNVKGVWAPPAPGFGEDVPNRLVDNIDMIDGDGDDMERFMEEMRELRRKIRELQLRYSLRILIGDPPHHDHHDEFCLMP
What are the official names of this protein?
Protein BEX5, Brain-expressed X-linked protein 5, NGFRAP1-like protein 1, Nerve growth factor receptor-associated protein 2.
What is the protein family that this protein belongs to?
Belongs to the BEX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_ACTP7
Sequence: MAKTPVRARKRVKKQIADGVAHIHASFNNTIVTITDRQGNALAWATAGGSGFRGSRKSTPFAAQVAAERCAEAVKEFGLKNLEVMVKGPGPGRESTIRALNAAGFRITNITDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: AROQ_MYCLB
Sequence: MTMVNIINGPNLGRLGRREPDVYGSTTHEQLSALIERAAVEFGIKAVVRQSDSESQLLDWIHLAADAGEPVILNAGGLTHTSVALRDACAELSAPFIEVHISNVHAREEFRRHSYLSPLATGVITGLGVQGYLLALRYLAEIAGN
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: YHAM_SALAR
Sequence: MFESKINPLWQRLILAVQEEVKPALGCTEPISLALAAAAAAAELDGTVERIDAWVSPNLMKNGMGVTVPGTGMVGLPIAAALGALGGDAKAGLEVLKDASAKAVADAKALLAAGHVAVMLQEPCNDILFSRAKVYSGDSWACVTIVGDHTNIVRIETDKGVVFTQADNAQEEEKASPLVVLSHTSLEEILAFVNAVPFDAIRFILDAARLNGALSQEGLRGSWGLHIGSTLAKQCDRGLLAKDLSTSILIRTSAASDARMGGATLPAMSNSGSGNQGITATVPVMVVAEHVGADDERLARALMLSHLSAIYIHHQLPRLSALCAATTAAMGAAAGMAWLIDGRYATIAMAISSMIGDVSGMICDGASNSCAMKVSTSASAAWKAVLMALDDTAVTGNEGIVAHNVEESISNLCSLACRSMQQTDKQIIEIMASKAH
What are the official names of this protein?
UPF0597 protein YhaM.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.
Protein: PUR7_EXISA
Sequence: MKAIYEGKAKALFETEEAGVLRVYYKDDATAFNGEKKESIDGKGILNNAITTQLFELMHDNKIPTHFIKQISDREQLVRRVDIIPLEVVVRNVAAGSLAKRLGWEEGTPLLAPIVEFYYKDDALGDPLLTEDHIRLLQVATHKEVETLRQLGLWVNDVLLDFFGQHGIDVIDFKLEFGKVDGTIILADEISPDTCRLWDKETKQKLDKDVFRRDLGSLTETYGQLLTRIGGNGQ
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: RNC_BACCZ
Sequence: MPYRKYREKKYETKYREAFKVFQEKIGITFTDEKLLIQAFTHSSYVNEHRKKPHEDNERLEFLGDAVLELTVSQYLFQKYPTMSEGELTKLRAAIVCEPSLVRFANELSFGGLVLLGKGEEMTGGRERPALLADVFEAFIGALYLDQGLETVWGFLKEIVYPKINEGAFSHVMDYKSQLQELIQRDGSGNIEYQILQEKGPAHNREFVSRVTLNNVALGLGSGKSKKEAEQQAAAEALKKLKEQL
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_STRPM
Sequence: MKIVISKPDKNKIRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQVIDDVAGVTLASASTLDKDVSKGTKTEQAVVVGKLVAERAVAKGISEVVFDRGGYLYHGRVKALADAARENGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: ARGB_BACC3
Sequence: MNDYIVVKCGGSMLDQLNDVFFDCIKKLQQQYKVVIVHGGGPEIDAKLKDCNINVEKRDGLRVTPKEVMDVVQMVLCGSTNKKLVMNLQKHNLLAVGCSGCDGNLLQVQPVSGEIGYVGEVSYVETALLKGLINMNYIPVIAPVGINDNEIYNINADTAAAGIAAALSAKELILITDVDGILHEGKLVKKTDESEIATFIEKGVITGGMIPKVQAALASLKMGVQKISIVNGTKDFTEDTGGCIGTTVTRGVSIV
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEPB_ECOBW
Sequence: MTEAMKITLSTQPADARWGEKATYSINNDGITLHLNGADDLGLIQRAARKIDGLGIKHVQLSGEGWDADRCWAFWQGYKAPKGTRKVVWPDLDDAQRQELDNRLMIIDWVRDTINAPAEELGPSQLAQRAVDLISNVAGDRVTYRITKGEDLREQGYMGLHTVGRGSERSPVLLALDYNPTGDKEAPVYACLVGKGITFDSGGYSIKQTAFMDSMKSDMGGAATVTGALAFAITRGLNKRVKLFLCCADNLISGNAFKLGDIITYRNGKKVEVMNTDAEGRLVLADGLIDASAQKPEMIIDAATLTGAAKTALGNDYHALFSFDDALAGRLLASAAQENEPFWRLPLAEFHRSQLPSNFAELNNTGSAAYPAGASTAAGFLSHFVENYQQGWLHIDCSATYRKAPVEQWSAGATGLGVRTIANLLTA
What is the function of this protein?
Probably plays an important role in intracellular peptide degradation.
What are the official names of this protein?
Peptidase B, Aminopeptidase B.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIBD_MYCTO
Sequence: MNVEQVKSIDEAMGLAIEHSYQVKGTTYPKPPVGAVIVDPNGRIVGAGGTEPAGGDHAEVVALRRAGGLAAGAIVVVTMEPCNHYGKTPPCVNALIEARVGTVVYAVADPNGIAGGGAGRLSAAGLQVRSGVLAEQVAAGPLREWLHKQRTGLPHVTWKYATSIDGRSAAADGSSQWISSEAARLDLHRRRAIADAILVGTGTVLADDPALTARLADGSLAPQQPLRVVVGKRDIPPEARVLNDEARTMMIRTHEPMEVLRALSDRTDVLLEGGPTLAGAFLRAGAINRILAYVAPILLGGPVTAVDDVGVSNITNALRWQFDSVEKVGPDLLLSLVAR
What is the function of this protein?
Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
What are the official names of this protein?
Riboflavin biosynthesis protein RibD.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the HTP reductase family.
Protein: VKTC8_DABSI
Sequence: HDRPKFCYLPADPGECLAHMRSF
What is the function of this protein?
Serine protease inhibitor that inhibits chymotrypsin.
What are the official names of this protein?
Kunitz-type serine protease inhibitor C8, BPTI-8, Chymotrypsin inhibitor 8, Chymotrypsin inhibitor B8, Chymotrypsin inhibitor C8.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: CYSN_PSYIN
Sequence: MSNDSNLLATDIEEYLRVHENKDLMRFITCGSVDDGKSTLIGRLLFDSKMIFEDHMAAIEKDSKKFNTTDNDFDLSLLVDGLQSEREQGITIDVAYRYFATEQRKFIIADTPGHEQYTRNMVTGASTCDLAIILIDARYGVQVQTRRHSYICSLLGIKHLVVAVNKMDAVDYDQAVYKKIKADYREFAKQLNIADIRFVPISALKGDNVVNESENMTWYPGSPLLRLLNTIQIDTDINDKFRLAVQYVNRPNLDFRGFCGTVASGEIRVGDTIQALPSGKQSKVKSIVTFDGELESAFAGMAITLTLEDEIDISRGNMIVRPHEKPTSSKNFVADLVWMTEEALHVDREYIIKAGAHSTFGSVISINNKVDVNTMEKCEANQLVLNEIGSCNFEVAEALHFDRYSENRATGAFIMIDRLTNATVGAGMISGSVEALAKTAPEYSAFEVEFNALVRKHYPHWETKDITKL
What is the function of this protein?
With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 1, ATP-sulfurylase large subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
Protein: CYAA_ECO57
Sequence: MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICLYTPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCHQSWLDSEERQLLQRKCSLLESWAASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHILLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLDPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVCEKLSRERACVGWRRAVLSQLVSEWGWDEARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPNIESIISHQPLEYNRYLNKLVAWAWFNGLLTSRTRLYIKGNGIVDLPKLQEMVADVSHHFPLRLPAPTPKALYSPCEIRHLAIIVNLEYDPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRNSWNEVRTLHFNGEQSMIEALKTILGKMHQDAAPPDSVEVFCYSQHLRGLIRTRVQQLVSECIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGAISHNKLHGLSVQVETNHVKLPAVVDGFASEGIIQFFFEETQDENGFNIYILDESNRVEVYHHCEGSKEELVRDVSRFYSSSHDRFTYGSSFINFNLPQFYQIVKVDGREQVIPFRTKSIGNMPPANQDHDTPLLQQYFS
What are the official names of this protein?
Adenylate cyclase, ATP pyrophosphate-lyase, Adenylyl cyclase.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISCR_SALA4
Sequence: MRLTSKGRYAVTAMLDVALNSEAGPVPLADISERQGISLSYLEQLFSRLRKNGLVSSVRGPGGGYLLGKDAGSIAVGEVISAVDESVDATRCQGKGGCQGGDKCLTHALWRDLSDRLTGFLNNITLGELVNNQEVLDVSGRQHTHDAPRASSRAQDAIDVKLRA
What is the function of this protein?
Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.
What are the official names of this protein?
HTH-type transcriptional regulator IscR.
Protein: LEUD_ECO5E
Sequence: MAEKFIKHTGLVVPLDAANVDTDAIIPKQFLQKVTRTGFGAHLFNDWRFLDEKGQQPNPDFVLNFSQYQGASILLARENFGCGSSREHAPWALTDYGFKVVIAPSFADIFYGNSFNNQLLPVKLSDAEVDELFALVKANPGIHFDVDLEAQEVKAGEKTYRFTIDAFRRHCMMNGLDSIGLTLQHDDAIAAYEAKQPAFMR
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: RL1_BURCH
Sequence: MAKISKRRQAFAAKVDRQKLYAIEDALSLVKECASAKFDESIDVAVQLGIDAKKSDQVVRGSVVLPAGTGKSVRVAVFAQGEKAEQARAAGAEIVGMEDLAEQIKAGQMDFDIVIASPDTMRIVGTLGQILGPRGLMPNPKVGTVTPDVATAVKNAKAGQVQFRVDKAGIIHATIGRASFEPTALRSNLSALIEALQKAKPATSKGVYLRKIALSSTMGVGVRVDHATLAAQ
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: FMRF_APLCA
Sequence: MRPWCQLALLACLSLKWLTSHVTAESFLCDDSELCENGYLRFGRSMSVEEPHFRLERRSYPPVVYHKRFLRFGRSQEPDIEDYARAIALIESEEPLYRKRRSADADGQSEKVLHRARREAESEHKSLEEVSPDTKQDVEKRDADDVLDAEKRFMRFGKRFMRFGRGSSDDDESGDDDVQDLTDIGDGLGGEGEVNKRFMRFGKRFMRFGKREDGEPDKRFMRFGKSMADNDLDKRFMRFGKRFMRFGKSLPDSEVDKRFMRFGKSVDGDVDKRFMRFGKSVDGDVDKRFMRFGKSVDGDVDKRFMRFGKSVDGDVDKRFMRFGKSVDGDVDKRFMRFGKSVDDDVDKRFMRFGKSVDGDVDKRFMRFGKSVDDAVDKRFMRFGKSVDSDLDKRFMRFGKSVGSDEVDKRFMRFGKSVGSDEVDKRFMRFGKSLGTDDVNKRFMRFGKSLGTDDVNKRFMRFGKSLGTEDVDKRFMRFGKSLGTDDVDKRFMRFGKSLGTDDVDKRFMRFGKSLGTEDVDKRFMRFGKSLGTDDVDKRFMRFGKSLGTEDVDKRFMRFGKRFMRFGRSVGDSKYRSASSESVMTTDSKQTTEQATNKS
What is the function of this protein?
FMRFamide induces contractions in visceral and somatic musculature as well as in the heart.
What are the official names of this protein?
FMRF-amide neuropeptides.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: SID2_CAEEL
Sequence: MPRFVYFCFALIALLPISWTMDGILITDVEIHVDVCQISCKASNTASLLINDAPFTPMCNSAGDQIFFTYNGTAAISDLKNVTFILEVTTDTKNCTFTANYTGYFTPDPKSKPFQLGFASATLNRDMGKVTKTIMEDSGEMVEQDFSNSSAVPTPASTTPLPQSTVAHLTIAYVHLQYEETKTVVNKNGGAVAVAVIEGIALIAILAFLGYRTMVNHKLQNSTRTNGLYGYDNNNSSRITVPDAMRMSDIPPPRDPMYASPPTPLSQPTPARNTVMTTQELVVPTANSSAAQPSTTSNGQFNDPFATLESW
What is the function of this protein?
Plays a role in RNA-mediated gene silencing by mediating endocytic uptake of double-stranded RNA (dsRNA) ingested from the environment into intestinal cells from the intestinal lumen.  Selective for dsRNAs of at least 50 bp.  Required for avoidance behavior induced by small RNAs derived from pathogenic bacteria such as P. aeruginosa (PubMed:32908307).
What are the official names of this protein?
Systemic RNA interference defective protein 2.
What are the subcellular locations of this protein?
Apical cell membrane; Single-pass type I membrane protein. Cytoplasm. Note=Localizes to the apical membrane of intestinal cells and also to punctate cytoplasmic structures.
Protein: RS14_STRPC
Sequence: MAKKSKIAKYQKQLQLIEQYADLRRDLKAKGDYESLRKLPRDSNPNRLKNRDKIDGRPHAYMRKFGVSRINFRDLAHKGQLPGVTKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: CAST3_HUMAN
Sequence: MSCRGRGAGGRWNSTSWSTGCKLPASPRRVSRCSPTGLIKLAFLFSKTRCKFFSLTETPEDYTIIVDEEGFLELPSSEHLSVADATWLALNVVSGGGSFSSSQPIGMTKIAKSVIAPLADQNISVFMLSTYQTDFILVLKRDLPFVTHTLSSEFTILWSVARL
What are the official names of this protein?
Putative protein CASTOR3P, CASTOR3 pseudogene, STAG3 opposite strand transcript protein.
What is the protein family that this protein belongs to?
Belongs to the GATS family.
Protein: LYTS_STAES
Sequence: MLNLFILLLERVGLIILLAYILMNINHFKTMMSERDKWRSKFQLIIIFGIFSMISNFTGIEIENGHIVSSDIYYHLSKDASMANTRVLTIGVSGLIGGPWVAIIVGIISGLCRLYIGGADAYTYLISSIVIAIISGYFGHQTIKQNTYPSIKKGAIIGAITEIIQMGCILLFTNNLHHAITLVSFIALPMIIINSLGTAIFLTIILSTIKQEEQMRAVQTHDVLQLANETLPYFRSGLNEKSAQQAAEIILKLMQVSAVAITNKKDILTHIGAGSDHHVARKEIITDLSKEVIQSGKLKVAHTREGIGCHHPNCPLEGAIVVPLYIHNEVAGTLKFYFTDNNIISTSDQQLAKGLANIFSSQLELGQAEMQGQLLKDAEIKSLQAQVNPHFFFNAINTISALVRIDSEKARRLLIQLSQFFRSNLNGARNNTITLQKELQQVAAYLSLEQARYPNRFNIHYRIDDQCQDALIPPFIIQILVENSIKHAFKNRKKNNHIDVDVSMKQDCLSISVQDNGQGIPADQLDTIGYTTVTSTTGTGNALVNLNKRLTGLFGTTSALNIQSSQSGTTVSCLIPYKSSKEEHFNESVNR
What is the function of this protein?
Member of the two-component regulatory system LytR/LytS that probably regulates genes involved in cell wall metabolism.
What are the official names of this protein?
Sensor protein LytS, Autolysin sensor kinase.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NTF2_ORYSJ
Sequence: MDADAVAKAFVEHYYRTFDTNRPALVSLYQDGSMLTFEGQQFLGAAAIAGKLGSLPFAQCHHDINTVDCQPSGPQGGMLVFVSGSLRTGPDEHPLKFSQMFQLLPAGGNFYVQNDMFRLNYG
What is the function of this protein?
Facilitates protein transport into the nucleus.  Could be part of a multicomponent system of cytosolic factors that assemble at the pore complex during nuclear import (By similarity).
What are the official names of this protein?
Nuclear transport factor 2, NTF-2.
What are the subcellular locations of this protein?
Cytoplasm.