PharMolix/UniProtQA huggingface dataset:
Protein: CLPP_DESVH
Sequence: MPVPIVIESTGRAERAYDIYSRLLKDRIVLLGTPIDDQVASLICAQLLFLESENPEKEIHMYINSPGGSVTAGMAIYDTMQYINSPVSTLCMGQAASMGALLLAAGAPGLRFSLPHSRIMIHQPSGGFQGQATDIDIQAREVLRLKQSLNAIMSQHTGKPLEQVALDTERDYFMGPEEAQAYGLIDRVLTSRSEATDTISK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FEOC_ECO5E
Sequence: MASLIQVRDLLALRGRMEAAQISQTLNTPQPMINAMLQQLESMGKAVRIQEEPDGCLSGSCKSCPEGKACLREWWALR
What is the function of this protein?
May function as a transcriptional regulator that controls feoABC expression.
What are the official names of this protein?
Probable [Fe-S]-dependent transcriptional repressor.
What is the protein family that this protein belongs to?
Belongs to the FeoC family.
Protein: HMHB1_HUMAN
Sequence: MEEQPECREEKRGSLHVWKSELVEVEDDVYLRHSSSLTYRL
What is the function of this protein?
Precursor of the histocomplatibility antigen HB-1.  More generally, minor histocomplatibility antigens (mHags) refer to immunogenic peptide which, when complexed with MHC, can generate an immune response after recognition by specific T-cells.  The peptides are derived from polymorphic intracellular proteins, which are cleaved by normal pathways of antigen processing.  The binding of these peptides to MHC class I or class II molecules and its expression on the cell surface can stimulate T-cell responses and thereby trigger graft rejection or graft-versus-host disease (GVHD) after hematopoietic stem cell transplantation from HLA-identical sibling donor.  GVHD is a frequent complication after bone marrow transplantation (BMT), due to mismatch of minor histocomplatibility antigen in HLA-matched sibling marrow transplants.  HB-1 is presented on the cell surface by MHC class I HLA-B44.  This complex specifically elicits donor-cytotoxic T lymphocyte (CTL) reactivity in B-cell acute lymphoblastic leukemia (B-ALL) after treatment by HLA-identical allogenic bone marrow transplantation (BMT).  It induces cell recognition and lysis by CTL.  However, HB-1 restricted expression in B-ALL cells and not in normal tissues may allow a specific CTL reactivity against B-ALL without the risk of evoking graft-versus-host disease.
What are the official names of this protein?
Minor histocompatibility protein HB-1.
Protein: RGPD8_HUMAN
Sequence: MRRSKADVERYVASVLGLTPSPRQKSMKGFYFAKLYYEAKEYDLAKKYICTYINVQERDPKAHRFLGLLYELEENTEKAVECYRRSVELNPTQKDLVLKIAELLCKNDVTDGRAKYWVERAAKLFPGSPAIYKLKEQLLDCEGEDGWNKLFDLIQSELYVRPDDVHVNIRLVELYRSTKRLKDAVAHCHEAERNIALRSSLEWNSCVVQTLKEYLESLQCLESDKSDWRATNTDLLLAYANLMLLTLSTRDVQENRELLESFDSALQSAKSSLGGNDELSATFLEMKGHFYMYAGSLLLKMGQHGNNVQWRALSELAALCYLIAFQVPRPKIKLREGKAGQNLLEMMACDRLSQSGHMLLSLSRGKQDFLKEVVETFANKIGQSALYDALFSSQSPKDTSFLGSDDIGKIDVQEPELEDLARYDVGAIRAHNGSLQHLTWLGLQWNSLPALPGIRKWLKQLFHRLPHETSRLETNAPESICILDLEVFLLGVVYTSHLQLKEKCNSHHSSYQPLCLPFPVCKQLCTERQKSWWDAVCTLIHRKAVPGNLAKLRLLVQHEINTLRAQEKHGLQPALLVHWAKYLQKTGSGLNSFYGQLEYIGRSVHYWKKVLPLLKIIKKNSIPEPIDPLFKHFHSVDIQASEIVEYEEDAHITFAILDAVNGNIEDAVTAFESIKSVVSYWNLALIFHRKAEDIENDALSPEEQEECRNYLTKTRDYLIKIIDDGDSNLSVVKKLPVPLESVKQMLNSVMQELEDYSEGGPLYKNGSLRNADSEIKHSTPSPTKYSLSPSKSYKYSPETPPRWTEDRNSLLNMICQQVEAIKKEMQELKLNSSKSASRHRWPTENYGPDSVPDGYQGSQTFHGAPLTVATTGPSVYYSQSPAYNSQYLLRPAANVTPTKGSSNTEFKSTKEGFSIPVSADGFKFGISEPGNQEKKREKPLENDTGLQAQDIRGRKKGRGVIFGQTSSTFTFADVAKSTSGEGFQFGKKDLNFKGFSGAGEKLFSSRYGKMANKANTSGDFEKDDDAYKTEDSDDIHFEPVVQMPEKVELVTGEEGEKVLYSQGVKLFRFDAEVRQWKERGLGNLKILKNEVNGKLRMLMRREQVLKVCANHWITTTMNLKPLSGSDRAWMWSASDFSDGDAKLERLAAKFKTPELAEEFKQKFEECQRLLLDIPLQTPHKLVDTGRAAKLIQRAEEMKSGLKDFKTFLTNDQTKVTEEENKGSGTGVAGASDTTIKPNAENTGPTLEWDNYDLREDALDDSVSSSSVHASPLASSPVRKNLFRFDESTTGSNFSFKSALSLSKSPAKLNQSGTSVGTDEESVVTQEEERDGQYFEPVVPLPDLVEVSSGEENEQVVFSHRAEIYRYDKDVGQWKERGIGDIKILQNYDNKQVRIVMRRDQVLKLCANHRITPDMSLQNMKGTERVWVWTACDFADGERKVEHLAVRFKLQDVADSFKKIFDEAKTAQEKDSLITPHVSRSSTPRESPCGKIAVAVLEEITRERTDVIQGDDVADAASEVEVSSTSETTTKAVVSPPKFVFVSESVKRIFSSEKSKPFAFGNSSATGSLFGFSFNAPLKSNNSETSSVAQSGSESKVEPKKCELSKNSDIEQSSDSKVKNLSASFPTEESSINYTFKTPEKEPPLWHAEFTKEELVQKLRSTTKSADHLNGLLREIEATNAVLMEQIKLLKSEIRRLERNQEREKSAANLEYLKNVLLQFIFLKPGSERERLLPVINTMLQLSPEEKGKLAAVAQDEEENPSRSSG
What are the official names of this protein?
RANBP2-like and GRIP domain-containing protein 8, Ran-binding protein 2-like 3, RanBP2-like 3, RanBP2L3.
Protein: SYT9_RAT
Sequence: MPGARDALCHQALQLLAELCARGALEHDSCQDFIYHLRDRARPRLRDPDISVSLLTLVVTACGLALFGVSLFVSWKLCWVPWRERGLFSGSKDNNQEPLNYTDTETNEQENSEDFLDPPTPCPDSSMKISHTSPDIPLSTQPGGQDNCAHAVRVQRQVTEPTPSARHNSIRRQLNLSNPDFNIQQLQRQEQLTGIGRIKPELYKQRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVHYNDLEARKLHFSVYDFDRFSRHDLIGQVVVDHFFDLADFPRECILWKDIEYVTNDNVDLGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPESIDQIHLSIAVMDYDRVGHNEVIGVCQVGNEAERLGRDHWSEMLSYPRKPIAHWHSLLEKR
What is the function of this protein?
May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.
What are the official names of this protein?
Synaptotagmin-9, Synaptotagmin 5, Synaptotagmin IX, SytIX, Synaptotagmin V.
What is the protein family that this protein belongs to?
Belongs to the synaptotagmin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein.
Protein: RPOZ_LACDA
Sequence: MRITYPSIDKLLDEVDSRYSLSVLAAKRAGELEAGKPGALDNYHNLKPVGQALEEIAAGKVTIDADPHGEADE
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: ISPG_MYCGA
Sequence: MYTRTKTKKVFVGDVQIGGQNKIVLQSMTIAKTKHVKKSLKEINDLVKEGADLVRIAVFDDADKRAIRKVVDQSPCPIIADIHFNPDYAIAAIKAGCKKIRLNPGNIKSKEKLREICLLANQYNIPIRVGVNSGSIPYDLMREYGVTSTAMIIAAQRYVRMLKRFGFDNIVISLKTSSALLSMQAYELGAKKFSYPLHLGITEAGTLINGTIKSVAGLTPLLLKGIGDTIRISLSTNPVDEIKVAKKMLNSLGLYENLVDVVACPTCGRLNFDLFKVTKEIEEFVKDLHFPLKVSILGCSVNGPGEAKEADIGIAGGKQEGIIFKKGVVVKSVKQEYLVDELKQMILEEYELFKKKNGK
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: PSD_BRUSI
Sequence: MSLTDTIRNTFVPIHREGYPFIAGFFVVSLILGWLWDPLFWIGMVLTVWCIYFYRDPERVTPMDDDLVISPADGKVSFVGLAVPPAELDLGYEPMTRVSVFMNVFSVHINRSPVRGKIDKVVHRPGKFLNAELDKASTENERNSVLIESPHGKVGVVQIAGLVARRIVCWSNQDDELSVGERFGLIRFGSRVDVYLPSDATVRVAVGQTAIAGETVLADYGTERGEPVVRIA
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HBAD_PHRHI
Sequence: MLSADEKQLILHAWEKVHTHQEDFGAEALERMFTVYPQTKTYFHHFDLHHGSEQIRRHGKKVVVALENAVHHMDNLSAALCKLSDLHAYNLRVDPVNFKLLSHCFHVVLAGHLGEEYSPQVHVAYDKFLAAVSDVLAEKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-D, Alpha-D-globin, Component CII, Hemoglobin alpha-D chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: KCY_PECAS
Sequence: MTVMAPVVTVDGPSGAGKGTLCKALAEALQWNLLDSGAIYRVLALAALHHHVDISSEDALVPLASHLDVRFVAEDGQLKVILEGEDVSHEIRTEAVGNTASQAAAFPRVREALLRRQRAFREAPGLIADGRDMGTVVFPDAPVKIFLDASAEERAQRRMLQLQGKGFNVNFERLLSEIKERDDRDRSRPVAPLVPAADALVLDSTEMTIDEVIARALAYAREILA
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIFK_METM7
Sequence: MEIFGNVVSGLGEGRFFVGLTPYKNKFKELTGFTPFEGTLNVKLKHNFNLDEFNPIEFDGFEIDGKKYFGGKVLLVKLFDKSGHSINCAIVAPKKTDHSKKTLELIAPVHLRKFLSLNNSDVVKIVI
What is the function of this protein?
Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN).
What are the official names of this protein?
Riboflavin kinase, RFK, CTP-dependent riboflavin kinase, CTP:riboflavin 5'-phosphotransferase, Flavokinase.
What is the protein family that this protein belongs to?
Belongs to the archaeal riboflavin kinase family.
Protein: VSP14_BOTJA
Sequence: MVLVRVVANLLILQLSYAQKVSELVVGGDECNINEHRSLVAIFNSTGFFCSGILLNQEWVLTASHCDSTNFQMKIGVHSKKTLNQDEQTRNPKEKIFCPNKKNDDALDKDLMLVRLDSPVSDSEHIAPLSLPSSPPSVGSVCRIMGWGSITPIQKTNPDVPHCANINLLDDAVCRAAYPELPAEYRTLCAGVPEGGIDTCNGDSGGPLICNGQFQGIVFYGAHPCGQAPKPGLYTKVIDYNTWIESVIAGNTAATCPP
What is the function of this protein?
Snake venom serine protease that shows non-specific action on fibrinogen (PubMed:30145175).  It preferentially degrades fibrinogen Aalpha (FGA), releasing fibrinopeptide A, and shows a lower activity on fibrinogen Bbeta (FGB), releasing fibrinopeptide B and other uncommon fibrinopeptides (PubMed:30145175).  Also shows low fibrinolytic activity compared to plasmin (PubMed:30145175).  Has high enzymatic activity on the substrates for activated protein C and factor XIa, and for thrombin (PubMed:30145175).  Shows a wide activity spectrum at different peptide sequences, with a preferential cleavage at Lys-|-Xaa over Arg-|-Xaa bonds (PubMed:30145175).
What are the official names of this protein?
Snake venom serine protease HS114, SVSP, BjSP, Thrombin-like enzyme HS114, SVTLE.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: VM1H5_DEIAC
Sequence: FPYQGSSIMLESGKVNDYEVVYPQRLAPLPEGAVQQKYEDTMQYEFKVNGETIGLHMEKSKGLFSKDYSETHYSPDGRKITTYPSVEDHCYYHGRIENYEDSTASISACNGLKGHFKIQGETYFIESLKLSDSEAHAVFKYENVEKEDETHKMCGVTQNWKSYDPIKKPSWVNLTPKQQTWPQTSVNLQLVVDRSMYAKYNSDSEKITQTLQERVNIMKEIFKPLNLDITLSVIEMWDKKDLITVKTAATDTLKLFPKWRQTDLLKRIDNDNAQLQTAVDFDGETVGLAFKGTMCDKRYSAGIIQDHSAIPLLMAVTMAHELGHNLGMDHDDTYKCNCNVCIMPPRLNTNPSKTFSDCSNNDYQKFLTDKKPKCIHKKSLKTDTVSTSVSGNEPLDDNVDGFHA
What is the function of this protein?
This probable venom zinc protease is not hemorrhagic when 3 ug are injected onto the back skin of guinea pig.
What are the official names of this protein?
Snake venom metalloproteinase H5, SVMP.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-I subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ASPG2_DROER
Sequence: MLAQSCCLRLLILLLLCKSTCSVWEKSHKYFRNRKLRERRIKWFGTKKTEIQPLLISTWNYTDANLQAWSVLQQGPQRTRMAVIQGCMACQNQRCGRLLAGGSSPDSEGTLTLEAAIMDGERLEYGAVAGMEGARNAILVADAVLRHTKHSLLVGKSATKFARSLGYKEEFLTDGRTKNVWKKWRSNGCQPNFWRDVRPSHTENCGPYTPLPEHLHQHPLHQEYAITQGQHDQLAFLALDAEGKLHVASQSSGAPFRIPGRVGDSAVPGAGIYADNKVGGAVASGDGDILMRHLPAFLAVEAMRAGKKPDQAAEWVVQRLLRHNTEFNGAVVVVNRRGIYAAACAGLDEFHFVVSGGKEYLSMARVERIKCLEREDEVVDDGPKGLFPTIPEKQAVPRG
What are the official names of this protein?
L-asparaginase-like protein GG20738.
What is the protein family that this protein belongs to?
Belongs to the Ntn-hydrolase family.
Protein: CLPX_BORPA
Sequence: MPEKKGSADAKVLHCSFCNKSQHEVRKLIAGPSVFICDECIDLCNDIIREEAQATARAAIRSELPTPAEIKTFLDQYVIGQTSPKRMLAVAVYNHYKRIRHGEIKGDEVELSKSNIMLIGPTGSGKTLLAQTLARMLNVPFVMADATTLTEAGYVGEDVENIIQKLLQNCNYDVEKAQRAIIYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPNQDFVQVDTTNILFIVGGAFDGLEKVIRDRTEKSGIGFSAAVRAKSERGVGELFSEAEPEDLIKFGLIPELVGRLPVVATLDELDEAALVQILTEPKNALVKQFQKLFAMEGAELDVRPDALKAISRKALKRKTGARGLRSILEGALLDTMYDLPSQGNVSRVVLEANAVEGDGKPLLIYADESEAASGEKAGRGEVRDAAA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: SPXH_STAA3
Sequence: MAGELRIMENKSREDINLSPVSKIEIYSFFDPFSSDCFKLSAILSKLRIEYNQYIRIRHILNPSLKVLTKCQAQSTSNFDNIALAYKAAELQGRVRAERFIHLMQNEIIPKRDIITESMICDCIQNAGIDLEVFKDDLQKSKLTESLKIDLHIAREMEIEQAPSLVFFSEDVHEEGLKVEGLYPYHIYTYIINELMGKPIEKNLPPKLETYIQQQQLVTMEELLTIYEWPEKLLNKELKKLAIQQKIEKLKYPDGDFWKSKMPKIKSK
What is the function of this protein?
Adapter protein required for efficient degradation of Spx by ClpXP under non-stress conditions.  Interaction with Spx stabilizes Spx and exposes the C-terminus of Spx for recognition and proteolysis by ClpXP.
What are the official names of this protein?
ClpXP adapter protein SpxH.
What is the protein family that this protein belongs to?
Belongs to the SpxH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XERS_STRP6
Sequence: MRRELLLEKIETYKAIMPWYVLDYYQSKLAVPYSFTTLYEYLKEYKRFFDWLMDADLTQAPKIADIDLSTLEHLTKKDLEAFVLYLRERPSLNTYSTKEGLSQTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLASRAENIKQKLFLGDETLAFLDYVDKEYEQKLSNRAKSSFRKNKERDLAIISLLLASGVRLSEAVNLDLKDVNLNMMIIEVIRKGGKRDSVNVAGFAKGYLESYLAVRQRRYKAEKQDLAFFLTEYRGVPNRMDASSIEKMVGKYSEDFKIRVTPHKLRHTLATRLYDATKSQVLVSHQLGHSSTQVTDLYTHIVNDEQKNALDNL
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.
What are the official names of this protein?
Tyrosine recombinase XerS.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECD_THEYD
Sequence: MRKGIYLRIALIAFTVILAIIFFLPNTPLFSYMPGWWKKNLPHKGIVLGLDLRGGSHLIFEVDLKRAREITVERIGMHLQSLLEKKGLKPSVKVQGEKIFIQPVNEDVKKIIKENYADLSISEHGGNIICELPETAFKRVETTSVEQAIEVIRNRIDQLGVAEPAIHKQGENEIVVQLPGVKDPKKALEIIGKTAQLEFKLLDEETTLWKQLPSLIKAGEEDTFLNQWKSKLPESDEIVFQKIVNKETGEVYKRPYIVKKDVLLTGDLLAEAHVSIDQRFNEPYVSLRFNDAGAKIFEDITGKYVKRRLAIILDGNLYSAPVIQEKIEGGNAQISGSFTLEEAKDLAIVLRAGALPAPVKLIQNVTVGPTLGKDSIEAGKMAVIIASIFVSLFMIIYYRLSGVIADFALILNIILLIGALAALNATLTLPGIAGIALAVGMAVDSNVLMFERIREELRLGKTPKAAIETGYKKAFWTIFDSHVTTLITAAVLFHFGSGPIKGFAVTLSLGVAINLFTALIGTKTVFDFIYIGKERKSLSI
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
What are the official names of this protein?
Protein translocase subunit SecD.
What is the protein family that this protein belongs to?
Belongs to the SecD/SecF family. SecD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRHO_RICRS
Sequence: MNEKIAILSAYSFVNIEEPANLIPKLLLLGKRKYIRGTILLANEGFNGSFSGSYENVNLVLEELIKLTGPKDVNVKINYSDVHPFQKLKVRLKKEIIAMNVDDLNVDLFKGEYIEPKDWDEFITKQDVIVIDTRNDYEVEVGTFKSAINPNTKTFKQFPAWVQQNQELLKGKKIAMVCTGGIRCEKSTSLLKSIGYNEVYHLKGGILQYLEDTQNKNNLWQGECFVFDDRRAVTDDLSPVERHWLQR
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: Y048_MYCPN
Sequence: MNELQTKVNEANNIFPVEAFKVPKVPEKLFGFVNQGFFPKLNPKGLNIADNVASLFEQYSLKQASLKDFDILLEKKNDIVLEHKVRYNFALQFHFETTYVGTGGEINLQFALQASTTNFSSLEELQASFSKTGDNLTAQLFWKPTVTKLVSGENDLTHIAQTAIGESLFDSRVDLSASIINSEATLKTAEATFTTQVLNPFKAEREKALAIKKAEEEKIKKELEEQKKRQEELSKQQRDKEALQKSLWNFQEFISYWTGQGKDVKQKEQFIQALEAAFSTNWNEVFNLLIAGFRSAIQTYYKDGKADQSQNAKIAFGEKGIQFPKSGPGLDGIFMSDFLRGNLTGNAHFDLKLKKVEVKNTQGKDAQGNDKKASINWQAKQNNFPFRQVNPWDFSFEVELKYEGSYGLYPGARFLNLFGSLGIPNDWKGEMSVKFVLDGKTPQWIADKPDYPGSLFKFEKNQLKFTPHVKEHVHVENKQFMEKLKSQNLHNLELATGATKPPVVDLASYLHYLILNHK
What are the official names of this protein?
Uncharacterized protein MPN_048.
What is the protein family that this protein belongs to?
Belongs to the MG032/MG096/MG288 family.
Protein: RLMN_RHIEC
Sequence: MSVMDAIVVKKPQAARPSSGAEKPSLIGLSREEMAAALREKGVPEKQIKMRVSQLWNWIYVRGVSDFDHMTNVAKDMREMLKQHFTIARPEIVEEQVSNDGTRKWLLRFPARGAGRPVEIEAVYIPEEGRGTLCISSQVGCTLTCSFCHTGTQRLVRNLTAEEILSQLLLARDRLGDFPDREAPQGTIMPAEGRKVSNIVMMGMGEPLYNFDAVKQALLIATDGDGLSLSKRRVTLSTSGVVPEIFRTGEEIGVMLAISLHAVRDDLRDILVPINKKYPLKELIDACKAYPGLSNARRITFEYVMLKDVNDSLEDAKGLIKLLKGVPAKINLIPFNPWPGTNYQCSDWEQIEKFADFINSAGYASPIRTPRGRDILAACGQLKSESERMRKTERLAFEAMMIANHGADD
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAND_GEOTN
Sequence: MFRTLMNAKIHRARVTEANLDYVGSITIDEDILDAVGMVANEKVQIVNNNNGARFETYIIPGERGSGVFCLNGAAARLVQKGDIIIVISYALVPEEKIAMHRPKVAIMDENNRIAQLIAEEPAHTIL
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STK24_HUMAN
Sequence: MDSRAQLWGLALNKRRATLPHPGGSTNLKADPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELARGEPPHSELHPMKVLFLIPKNNPPTLEGNYSKPLKEFVEACLNKEPSFRPTAKELLKHKFILRNAKKTSYLTELIDRYKRWKAEQSHDDSSSEDSDAETDGQASGGSDSGDWIFTIREKDPKNLENGALQPSDLDRNKMKDIPKRPFSQCLSTIISPLFAELKEKSQACGGNLGSIEELRGAIYLAEEACPGISDTMVAQLVQRLQRYSLSGGGTSSH
What is the function of this protein?
Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation.  Mediates oxidative-stress-induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress.  Plays a role in a staurosporine-induced caspase-independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG.  Phosphorylates STK38L on 'Thr-442' and stimulates its kinase activity.  In association with STK26 negatively regulates Golgi reorientation in polarized cell migration upon RHO activation (PubMed:27807006).  Regulates also cellular migration with alteration of PTPN12 activity and PXN phosphorylation: phosphorylates PTPN12 and inhibits its activity and may regulate PXN phosphorylation through PTPN12.  May act as a key regulator of axon regeneration in the optic nerve and radial nerve.
What are the official names of this protein?
Serine/threonine-protein kinase 24, Mammalian STE20-like protein kinase 3, MST-3, STE20-like kinase MST3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Membrane. Note=The truncated form (MST3/N) translocates to the nucleus. Colocalizes with STK38L in the membrane.
Protein: DYS7_LIMSA
Sequence: GAVSGLLTNLGL
What are the official names of this protein?
Dynastin-7.
What are the subcellular locations of this protein?
Secreted.
Protein: RL34_LACLM
Sequence: MKRTYQPHKKSRKTTHGFRSRMATKNGRRVLAARRRKGRASLTV
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: DHAR1_ORYSJ
Sequence: MGVEVCVKAAVGHPDTLGDCPFSQRVLLTLEEKKVPYEMKLIDVQNKPDWFLKISPEGKVPVFNGGDGKWIPDSDVITQVIEEKYPTPSLVTPPEYASVGSKIFSCFTTFLKSKDPNDGSEKALLTELQALEEHLKAHGPFINGQNISAADLSLAPKLYHLQVALEHFKGWKIPEDLTNVHAYTEALFSRESFIKTKAAKEHLIAGWAPKVNA
What is the function of this protein?
Involved in ascorbate homeostasis.  Maintains redox pools of ascorbate by recycling dihydroascorbate (DHA) to ascorbate (Probable).  Involved in scavenging reactive oxygen species (ROS) under oxidative stresses.  Possesses dehydroascorbate reductase (DHAR) activity in vitro (PubMed:19011360).  May function via a ping-pong reaction mechanism with an electron transfer at the active site (PubMed:26775680).  Possesses chaperone-like activity in vitro (PubMed:26775680).
What are the official names of this protein?
Probable glutathione S-transferase DHAR1, cytosolic, GSH-dependent dehydroascorbate reductase 1, OsDHAR1, Glutathione-dependent dehydroascorbate reductase 1.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. DHAR family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: EI3F1_DROSI
Sequence: MSALNLTVRVHPVVLFQVVDAFERRNADSHRVIGTLLGSVDKGVVEVTNCFCVPHKEHDDQVEAELSYALDMYDLNRKVNSNESVVGWWATGNDVTNHSSVIHEYYARECNNPVHLTVDTSLQGGRMGLRAYVCIQLGVPGGKSGCMFTPIPVELTSYEPETFGLKLLQKTVGVSPAHRPKTVPPMLDLAQISEASTKLQSLLDLILKYVDDVIAHKVTPDNAVGRQLLDLIHSVPHMTHEQFTQMFNANVRNLLLVITLSQLIKTQLQLNEKLTFLPTA
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit F-1, eIF3f-1, Eukaryotic translation initiation factor 3 subunit 5-1.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit F family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSCL_RHIEC
Sequence: MLNEFKAFIARGNVMDLAVGVIIGGAFGGIVKSLVDDLIMPIVGAIFGGFDFSNYFLPLSSAVNAPTLAAARAQGAVFAYGSFLTVLINFLILAWIIFLMVKAVNYLRQQVERQEKQEPEQLPPPPADVQLLTEIRDLLAKRPAV
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.