PharMolix/UniProtQA huggingface dataset:
Protein: SYGB_CERS4
Sequence: MPDLLIELFSEEIPARMQARAREDLKKLVTDGLVEAGLTYASAGAFSTPRRLVLSVEGLSAESPTLREERKGPKADAPAAAIEGFLRSTGLTRDQLETREDKKGAVLFAVVEKPGRPAPEIVAEVLERTIRTFPWPKSMRWGTGSLRWVRPLQSILCLLSDEAGAEVVPMTLDGLTAGNSTEGHRFMAPARFAVSGFEDYRAKLARAFVMLDASEREQAIWHEATTQAFAQGLEVVPDAALLSEVAGLVEWPVVLMGAIGEDFLGLPPEVLQTSMREHQKFFSVTNPATGRIEKFVTVANRETADHGETILKGNGKVLSARLSDARFFWENDLRTVKTAGLEGMAEGLKQVTFHNRLGSQAARIARIEALAREIAPLVGASPDLAAEAARVAKADLQSAMVGEFPELQGTMGSYYARAAGLPEAVAQACKAHYQPLGPSDAVPTDPVSVAVALADKIDTLAGFWRIGEKPTGSKDPFALRRAALGVIRLLLTNNSRAGLMGIMLPAMNRHLEPFDTSDFTPYERDLLAFFHDRLKVHLREQGIRHDVIDACLAMPGNDDLTLLVKRAEALSAFLKTDDGTNLLQGFKRANNILTQAEAKDGVEYSFGADPKFAETDAERALFAALETAEAAIGPALQAEDFAAAMSAMAALRAPIDAFFETVQVNADNAVLRRNRLNMLHSIRATCARVADLTRIEG
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CUE2B_XENLA
Sequence: MALEKIIRESLTGFLQCHIAHADLSALDEVFCAYVTGVLEELGSQNSSEEDFEMESFVEMLEGYIPGFSEISSEKVYDMLFELSGRLSEARGTENVSPNPTVEVSFMTPASPSEKTATEPLEGAVAQDKDDPKTGVDLLLEIFPSCTITQAQTALSMAKGDLEDAVQIIVDGKVIADNHSGSKDMQGAPKIEDLKDFILQKYMLVDTEDDKKTYRPVAPKEAPKKMIRYIDNQVVSTKGERYKDIKKPESEEMKKTYINLKPARKYKFH
What is the function of this protein?
May play a role in targeting proteins for ubiquitination and subsequent proteasomal degradation.
What are the official names of this protein?
CUE domain-containing protein 2-B.
What is the protein family that this protein belongs to?
Belongs to the CUEDC2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: AP2S_YEAST
Sequence: MAVQFILCFNKQGVVRLVRWFDVHSSDPQRSQDAIAQIYRLISSRDHKHQSNFVEFSDSTKLIYRRYAGLYFVMGVDLLDDEPIYLCHIHLFVEVLDAFFGNVCELDIVFNFYKVYMIMDEMFIGGEIQEISKDMLLERLSILDRLD
What is the function of this protein?
Component of the adaptor complexes which link clathrin to receptors in coated vesicles.  Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
What are the official names of this protein?
AP-2 complex subunit sigma, Adaptin small chain, Clathrin assembly protein 2 sigma small chain, Clathrin coat assembly protein AP17, Clathrin coat-associated protein AP17, Plasma membrane adaptor AP-2 17 kDa protein, Sigma2-adaptin.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes small subunit family.
What are the subcellular locations of this protein?
Cell membrane. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of the plasma membrane coated vesicles.
Protein: FMT_WOLPP
Sequence: MRIIFMGSPGFAVGALNLLLKLQSEVVAVYTKAPKPSGRRQRLTKSPVHIVAEKSDIEVCTPASLKSSIEQEKFGNFKPDVAVVAAYGLILPKEILNIPKYGCINIHPSLLPRWRGAAPIQHTILAGDQETGVSIMQLDEGLDSGPILKQKKFLIEKSDNYKTLYDKLSELGSDLLLKVLNEIEKQVPLKQSDNDACYADKVKDYKIYASDACEIAYRKVKAFYPKAFIKVENKRIKILDAEFEAFTSGQGEIINDNMHISLKGGTLIPKVVQMEGRNPCDIKDFVRGLKSSLTKKFIE
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: MCSB_CLOK5
Sequence: MNNWVTTYENHNYGLVISSRIRLARNLAKIPFSHKLNIEESKKVIKNVENAFYTFSNTEEKFKSNYLWDKNDNEKNIYLEKHLISKNLIDNSSKAAFILDDKETISIMINEEDHVRIQCITGGLNLEEVYDVSEKIDDLLEENLEYAFDEKLGYLTACPTNVGTGLRASVMLHLPSLSLNNQINGFLNALAQVGMTIRGLYGEGSKAIGNIYQISNQVTLGRSEEEILSNLKALVLQIINQEIISRENLMKKYKYELEDKIYRALGVLKSAVLLNSSECLKLLSDVRLGVEMGIIKDVNGITLNKLLVESQPATIQKIYGESLSNKDRDFNRAKFVREKLAVNTA
What is the function of this protein?
Catalyzes the specific phosphorylation of arginine residues in proteins.
What are the official names of this protein?
Protein-arginine kinase.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.
Protein: PLSY_ALIF1
Sequence: MTPLALIMIIIAYLLGSISSAVLICRLKGLPDPRTSGSHNPGATNVFRIGGRSAAGLVLLCDILKGMLPVWGGYFLEINPFMLGIIAISACLGHMYPLFFHFKGGKGVATALGALAPIGLDLTGMLFGCWVVTVLVTGYSSLASMITALLAPLFTWLVKPQYTLPVAMLSCLIVLKHHENIKRFFEGKETKIWQRKRD
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS5_BURMS
Sequence: MAKMQAKVQADERDDGLREKMISVNRVTKVVKGGRILGFAALTVVGDGDGRVGMGKGKAKEVPVAVQKAMEQARRNMFKVPLKNGTLQHEVHGKHGASTVLLAPAKDGTGVIAGGPMRAVFDVMGVQNVVAKSHGSTNPYNLVRATLDGLRKQSTPADIAAKRGKSVEEILG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: ZFP1_PONAB
Sequence: MNKSQGSVSFTDVTVDFTQEEWEQLDPSQRILYMDVMLENYSNLLSVEVWKADDQMERDHRNPDEQARQFLILKNQTPIEERGDLFGRALNLNTDFVSLRQVPYKYDLYEKTLKYNSDLLNSNRSYAGKQTDECNEFGKALLYLKQEKTHGGVEYSEYNKGGKALSHKAAIFKHQKIKNLVQPFICTYCDKAFSFKSLLISHKRIHTGEKPYECNVCKKTFSHKANLIKHQRIHTGEKPFECPECGKAFTHQSNLIVHQRAHMEKKPYECSECGKTFAQKFELTTHQRIHTGERPYECNECAKTFFKKSNLIIHQKIHTGEKRYECSECGKSFIQNSQLIIHMRTHTGEKPYECTECGKTFSQRSTLRLHLRIHTGEKPYECSECGKAFSRKSRLSVHQRVHIGEKP
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 1 homolog, Zfp-1.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Note=Shows widespread expression throughout the nucleus, but appears to be excluded from nucleoli.
Protein: AES_SALPA
Sequence: MKPENKIPVLTRLSDEMKAVVNFQQPGLPPWPADGDIETQRQYYLLERRFWNADAPSMTTRTCAVPTPYGDVTTRLYSPQPTSQATLYYLHGGGFILGNLDTHDRIMRLLARYTGCTVIGIDYSLSPQARYPQAIEETVAVCSYFSQHADEYSLNVEKIGFAGDSAGAMLALASALWLRDKHIRCGNVIAILLWYGLYGLQDSVSRRLFGGAWDGLTREDLDMYEKAYLRNDEDRESPWYCLFNNDLTRDVPPCFIASAEFDPLIDDSRLLHQTLQAHQQPCEYKMYPGTLHAFLHYSRMMTIADDALQDGARFFMARMKTPR
What is the function of this protein?
Displays esterase activity towards short chain fatty esters (acyl chain length of up to 8 carbons).  Able to hydrolyze triacetylglycerol (triacetin) and tributyrylglycerol (tributyrin), but not trioleylglycerol (triolein) or cholesterol oleate.  Negatively regulates MalT activity by antagonizing maltotriose binding.  Inhibits MelA galactosidase activity.
What are the official names of this protein?
Acetyl esterase.
What is the protein family that this protein belongs to?
Belongs to the 'GDXG' lipolytic enzyme family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPE1A_STRPU
Sequence: MAAQLLFTDEEVTEFKRRFKNKDTDKSKSITAEELGEFFKSTGKSYTDKQIDKMISDVDTDESGTIDFSEMLMGIAEQMVKWTWKEEHYTKAFDDMDKDGNGSLSPQELREALSASKPPMKRKKIKAIIQKADANKDGKIDREEFMKLIKSC
What is the function of this protein?
Calcium-binding protein involved in larval development and metamorphosis.  Likely to function as calcium buffers mediating the transport of calcium from the sea water to the blastocoel where calcium is required for skeleton formation.
What are the official names of this protein?
Calcium-binding protein SPEC 1A.
Protein: TRPF_PSEPW
Sequence: MSNVRSKICGITRIEDALAAAEAGADAIGFVFYAKSPRAVDVRQARAIMAELPPFVTTVGLFVNASRCELNEILEAVPLDLLQFHGDETPADCEGYHRPWIKALRVRPGDDLEAACRHYAGARGILLDTYVAGVPGGTGEAFDWSLVPSRLSKPIILAGGLSAGNVGQAIAQVRPYAVDVSGGVEQAKGIKDAAKIEAFMRAVKQA
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: CLPP_NITMU
Sequence: MQRFEWKQRNHEPQDLGLIPMVIETSGRGERAYDIYSRLLRERVIFLVGPVTEASANLIVAQLLFLESENADKDIHFYINSPGGLVSAGMAVYDTMQFIKPDVSTLCIGQAASMGSLLLAAGAKGKRFCLPNSRVMIHQPLGGFQGQASDIEIHAREILYLKNRLNELLSKHTGQSMETIERDTDRDNFLGAEDSVKYGLVDAVLTSRGEGAG
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS7_DECAR
Sequence: MRQAEITRNTLETQITVRLNLDGTGQGKYATGVPFLDHMLDQIARHGLIDLDIEAKGDLHIDAHHTVEDIGITFGQALAKAWGDKKGLTRYGHSYVPLDEALSRVVIDLSGRPGLELHVEFTRAVIGTFDVDLVGEFFHGLVNHAGMTLHIDNLRGKNAHHQAETIFKAFGRALRMAVTPDPRMAGTMPSTKGSL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_PICTO
Sequence: MIDNGSMFIAIEGIDGSGKTTLAGDIASYTGFYLTREPTDRFCYDYIEADYNDESSIINFFLFTLDRYMHQKEIKNHLINGVISDRYVFSSIAYQGSGMEKRFKNMDETISWMLDVSRFIIMPDLIIYLKIDPGIALKRLNLRKNEKKNTDAFERLEMLKNVSKYYDYIFSGIIKIPVIKINAEMEYNYVKDEAIKGLNDYL
What are the official names of this protein?
Probable thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: SAHH_PARMW
Sequence: MVAAPTTATELKLGVDCVIADINQAAFGRKELDIAETEMPGLMALREKYGTEKPLKGARIAGSLHMTIQTACLIETLVELGAEVRWASCNIFSTQDHAAAAIAAQNIPVFAVKGETLEEYWEYTHRILEWGDGGSPNMILDDGGDATGLVMLGSKAEQDITVLDNPSNEEETFLFASIKKKLAQDPTFYSRTKAEIQGVTEETTTGVARLYKMQKSGELPFPAINVNDSVTKSKFDNLYGCRESLVDSIKRATDVMVAGKQALVMGYGDVGKGSAQSLRGLGATVCIAEVDPICALQAAMEGYRVVRLEDVVEEMDIFVTATGNYQVIRNEHLEKMKDEAIVCNIGHFDNEIDVASLKGYEWDNIKPQVDHITLPSGNRIILLAEGRLVNLGCATGHPSFVMSNSFTNQVLAQIELFTKGNEYGKEVYVLPKHLDEMVARLHLDRIGAKLTELSKDQADYINVPVEGPYKPDHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANSME_CLOP1
Sequence: MPPLSLLIKPASSGCNLKCTYCFYHSLSDNRNVKSYGIMRDEVLESMVKRVLNEANGHCSFAFQGGEPTLAGLEFFEKLMELQRKHNYKNLKIYNSLQTNGTLIDESWAKFLSENKFLVGLSMDGPKEIHNLNRKDCCGLDTFSKVERAAELFKKYKVEFNILCVVTSNTARHVNKVYKYFKEKDFKFLQFINCLDPLYEEKGKYNYSLKPKDYTKFLKNLFDFWYEDFLNGNRVSIRYFDGLLETILLGKSSSCGMNGTCTCQFVVESDGSVYPCDFYVLDKWRLGNIQDMTMKELFETNKNHEFIKLSFKVHEECKKCKWFRLCKGGCRRCRDSKEDSALELNYYCQSYKEFFEYAFPRLINVANNIK
What is the function of this protein?
Involved in 'Cys-type' sulfatase maturation under anaerobic conditions.  Catalyzes the post-translational modification of cysteine ('Cys-51' in the arylsulfatase CPF_0221) into 3-oxoalanine (also known as C(alpha)-formylglycine (FGly)), by a free radical chemical mechanism initiated via the reductive cleavage of S-adenosyl-L-methionine (SAM) (PubMed:18408004, PubMed:16766528, PubMed:17335281, PubMed:19489556, PubMed:23477283).  Is also able to oxidize a serine residue in a synthetic substrate to FGly in vitro, and in a serine variant of a Cys-type sulfatase in vivo, but this activity is not physiological (PubMed:18408004, PubMed:23477283).  Converts threonyl peptides to the corresponding ketone product, and also allo-threonyl peptides, but with a significantly reduced efficiency (PubMed:23477283).
What are the official names of this protein?
Cysteine-type anaerobic sulfatase-maturating enzyme, Cys-type anaerobic sulfatase-maturating enzyme, Anaerobic sulfatase-maturating enzyme, AnSME, anSMEcpe.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.
Protein: RL15_RUBXD
Sequence: MRLNELSPPPGSRRARKRVGRGEGSGYGKTSGRGQKGAKARSGTKAYTTYEGGQMPLQRRLPRLKGEARGRHTPAHPKVYDPVNVGELAAVEGDTIGLDELRAAGLIRKKADTLVKILGDGEIDRPVTVRAHAFSRAAREKIEAAGGRAEVL
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: HEM6_COXBU
Sequence: MRKDRQNKITEVGIYLKDLQNRLCRAFEKEEGESRFQETLWEKPNGGGGRTRLLTEGHVIEQGGVNFSCVYGNQLPPAATQKHPEISGFAFQAEGLSLVIHPRNPYVPTVHANFRFFIAGKDEADPRWWFGGGYDLTPYYGFEEDCRHWHRVAKKACDRFGEAIYPRFKAACDDYFYLKHRNEPRGIGGLFFDDLNEWEFKRCFEFIKILGDSFLEAYLPIMQNRKNHPYGERQREFQLYRRGRYVEFNLLYDRGTRFGLEFGGRTESILMSLPPRVVWRPNWEPEPGSEEARLYEDYLVRRNWVSVSGA
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPCKG_METAR
Sequence: MIYKLTPALRDDLKTPFGTLYPGKGESCLAKVVKALDKPPKIISIGDVTTFYLIKAGVVPDMCLVDDQTMRLPVDHEVRKGTSHHTFKELRVSNPAGVVTQALMDLIKDNMSSTEPVRIFVDGEEDLAVIPACLYAPIGSAVIYGQPNEGVVVVRVTEEKRKETKALLDKMERVDE
What is the function of this protein?
Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
What are the official names of this protein?
GTP-dependent dephospho-CoA kinase, Dephospho-coenzyme A kinase, DPCK.
What is the protein family that this protein belongs to?
Belongs to the GTP-dependent DPCK family.
Protein: RS3_BUCBP
Sequence: MGQKVHPNGMRLGIIKHWNSVWFSNSKDFAKILDSDYQVRLFLRKELFKASVSRIVIERPSKSIRVTIYSARPGIVIGKKGEDVEKLRLSITNITGVPTQINIAEIRKPELDAKLVADNIVSQLERRIMFRRAMKRAVQNAMRQGAKGIKVEISGRLGGTEIARREWYREGRVPLHTLRADIEYNVSEAHTTYGVIGVKVWIFKGEILGGIGSIPKIEKQKPMSQLKKHQRRYRK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: OPGH_PSEPF
Sequence: MSNSQVQPETLSEYLAHLPMTDEQRAELAGCQSFSELHERLSSKTFDAPTEAAQASVGKRLILSTAEELQDAEMLVLDASGRVSMKATPPIRRTKVVPEPWRTNILVRGWRRLTGRTNPPQPPKDANVLPAARWRTVGSIRRYILLVLMLGQTIVAGWYMKGIMPYQGWSFVDLEEVLHQPLLQTATQVLPYALQTSILIMFGILFCWVSAGFWTALMGFLELLTGHDKYRISGKSAGNEPIPKDARTALVMPICNEDVPRVFAGLRATFESVAATGDLDRFDFFVLSDSNDTDICVAEQQAWLDVCREAKGFGKIFYRRRRRRVKRKSGNLDDFCRRWGGDYKYMVVLDADSVMSGECLTSLVRLMEATPDAGIIQTAPRASGMDTLYARMQQFATRVYGPLFTAGLHFWQLGESHYWGHNAIIRMKPFIDHCALAPLPGKGAFSGAILSHDFVEAALMRRAGWGVWIAYDLPGSYEELPPNLLDELKRDRRWCHGNLMNFRLFLVKGMHPVHRAVFLTGVMSYLSAPLWFFFLVLSTALLAVNTLMEPQYFLEPRQLYPLWPQWHPDKAIALFSTTIVLLFLPKLLSIILIWAKGAKEFGGKFKVTLSMLLEMLFSMLLAPVRMIFHTRFVLAAFLGWAATWNSPQRDDDSTPWSEAVKRHGPQTLLGFFWALLVIWLNPSFLWWLVPIVGSLMLSIPVSVISSRVGLGLKSRDESLFLIPEEYNPPQALLATDQYTHENRWHALNDGFVRAVVDPQQNALACSLATSRHGQAEPIEWLRQERVRHAIKVGPAGLNNHDRLQLLSDPVALARLHEQVWAEGHAEWLDAWRASVKADPHAPLLPLKPVSLQAQPA
What is the function of this protein?
Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis glucosyltransferase H.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. OpgH subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IGS21_RAT
Sequence: MRAAPSLRRASCLLLAAILDLARGYLTVNIEPLPPVVAGDAVTLKCNFKTDGRMREIVWYRVTDGGTIKQKIFTFDAMFSTNYSHMENYRKREDLVYQSTVRLPEVRISDNGPYECHVGIYDRATREKVVLASGNIFLNVMAPPTSIEVVAADSPAPFSRYQAQNFTLVCIVSGGKPAPMVYFKRDGEPIDAVPLTELPASSSGSVQDSRPFRSLLHRDVDDTKMQKSLSLLDTEYRAGRPYTERPSRSLTQDPNLFVQPTTENIPETVVSREFPRWVHSAEPVYFLRHSRTPGSDGTVEVRALLTWTLNPQIDNEALFSCEVKHPALSMPMQAEVTLVAPKGPKIMMTPSRARVGDTVRILVHGFQNEVFPEPMFTWTRVGSRLLDGSAEFDGKELVLERVPAELNGSMYRCTAQNPLGSTDTHTRLIVFENPNIPRGTEDSRGSASGPTGVRLTLVLALTVILELT
What is the function of this protein?
Involved in synaptic inhibition in the brain.  Selectively regulates inhibitory presynaptic differentiation through interacting with presynaptic NRXN2.
What are the official names of this protein?
Immunoglobulin superfamily member 21, IgSF21.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Lipid-anchor, GPI-anchor.
Protein: HLYC_RICCK
Sequence: MFKSSKKEDSSKKNHNNKLIFAIRKLFSPIKNFFRQTKTPDNFFGVIKRLKINNQKMTLDECNIFANLLKIKDKTIADIMVPRSDIAAIKLTTNLEELSESIKLKVLHARTLIYDGTLDNVVGFIHIKDLFKAFATKQNGCLKKLIRKHIIAAPSMKLLDLLTKMRRERTHIAIVVDEYGGTDGLVTIEDLIEEIVGRIDDEHDQQLDSDNLKVINNSTIILNARVEVEVLEEIIGEKLKNDDEFDTIGGLVLTRVGSVPAIGTRINISENIEIEVTDATPRSLKQVKIRLKNALNSG
What are the official names of this protein?
Possible hemolysin C.
What is the protein family that this protein belongs to?
Belongs to the UPF0053 family. Hemolysin C subfamily.
Protein: V11_SPTNK
Sequence: MSFNKDEFVAFVNAIAMPIEMKNKIQSYIESLLNELENVKKSKNDLRISLQTSMNDANVLYHRQNNELKQKLNEITDELNEYKYENKKLQKENTSIQQIYVAKFYELNNMNKMYKKMLDLQTQMNELKSKKDIFEEQFMILENEHPTFLEKNQPIISEEEDD
What are the official names of this protein?
Uncharacterized protein V11.
Protein: HTPX_BUCAT
Sequence: MTRIVLFLLTNLAVMLIFSLILFLTGIQSNTIYGLLIMSGLFGFSGSILSLILSKWIALRSVNGEIITHPRNEVESWLINTVRQQSIQKGIIMPQIAVYHATDINAFATGARRNSALIAVSTGLLENMTHHEAEAVIAHEISHIANGDMITMTLVQGVVNTFVIFISRFLSQIISNVMSSNRNENNTEEKNSFVYFLVSTFLELIFGILASIITMWFSRHREFYADASSAKMVGREKMIAALNRLKTSHEPQESDSMIAFCINGKSKSFLKLFASHPSLENRIEALYNQEYM
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: X_HBVC1
Sequence: MAARVCCQLDPARDVLCLRPVGAESRGRPVSGPFGPLPSPSSSAVPADHGARLSLRGLPVCAFSSAGPCALRFTSARRMETTVNAHQVLPKVLHKRTLGLSAMSTTDLEAYFKDCLFKDWEELGEEIRLMVFVLGGCRHKLVCSPAPCNFFTSA
What is the function of this protein?
Multifunctional protein that plays a role in silencing host antiviral defenses and promoting viral transcription.  Does not seem to be essential for HBV infection.  May be directly involved in development of cirrhosis and liver cancer (hepatocellular carcinoma).  Most of cytosolic activities involve modulation of cytosolic calcium.  The effect on apoptosis is controversial depending on the cell types in which the studies have been conducted.  May induce apoptosis by localizing in mitochondria and causing loss of mitochondrial membrane potential.  May also modulate apoptosis by binding host CFLAR, a key regulator of the death-inducing signaling complex (DISC).  Promotes viral transcription by using the host E3 ubiquitin ligase DDB1 to target the SMC5-SMC6 complex to proteasomal degradation.  This host complex would otherwise bind to viral episomal DNA, and prevents its transcription.  Moderately stimulates transcription of many different viral and cellular transcription elements.  Promoters and enhancers stimulated by HBx contain DNA binding sites for NF-kappa-B, AP-1, AP-2, c-EBP, ATF/CREB, or the calcium-activated factor NF-AT.
What are the official names of this protein?
Protein X, HBx, Peptide X, pX.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus protein X family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Host mitochondrion. Note=Mainly cytoplasmic as only a fraction is detected in the nucleus. In cytoplasm, a minor fraction associates with mitochondria or proteasomes.
Protein: DNAJ1_CHLAE
Sequence: MVKETTYYDVLGVKPNATQEELKKAYRKLALKYHPDKNPNEGEKFKQISQAYEVLSDAKKRELYDKGGEQAIKEGGAGGGFGSPMDIFDMFFGGGGRMQRERRGKNVVHQLSVTLEDLYNGATRKLALQKNVICDKCEGRGGKKGAVECCPNCRGTGMQIRIHQIGPGMVQQIQSVCMECQGHGERISPKDRCKSCNGRKIVREKKILEVHIDKGMKDGQKITFHGEGDQEPGLEPGDIIIVLDQKDHAVFTRRGEDLFMCMDIQLVEALCGFQKPISTLDNRTIVITSHPGQIVKHGDIKCVLNEGMPIYRRPYEKGRLIIEFKINFPENGFLSPDKLSLLEKLLPERKEVEETDEMDQVELVDFDPNQERRRHYNGEAYEDDEHHPRGGVQCQTS
What is the function of this protein?
Co-chaperone for HSPA8/Hsc70.  Plays a role in protein transport into mitochondria via its role as co-chaperone.  Functions as co-chaperone for HSPA1B and negatively regulates the translocation of BAX from the cytosol to mitochondria in response to cellular stress, thereby protecting cells against apoptosis.  Stimulates ATP hydrolysis, but not the folding of unfolded proteins mediated by HSPA1A (in vitro).  Promotes apoptosis in response to cellular stress mediated by exposure to anisomycin or UV (By similarity).
What are the official names of this protein?
DnaJ homolog subfamily A member 1, DnaJ protein homolog 2, DJ-2, Mydj2.
What are the subcellular locations of this protein?
Membrane; Lipid-anchor. Cytoplasm. Microsome. Mitochondrion. Nucleus. Cytoplasm, perinuclear region. Note=Primarily cytoplasmic and associated with microsomes. A minor proportion is associated with nuclei and mitochondria (By similarity).
Protein: ALO_KLULA
Sequence: MSFDLVAGNARSNFVFKNWAGIYSCRPQLYFQPNSIDEVVQIVKAAIEQGKTIVTVGSGHSPSDMCVTDQWLMNLDNLNSVVEFKENKEELYADVTVEAGLRIYQLSEILAEKGYAIQNLGSISEQSVAGIISTGTHGSSPYHGLVSSQYVNLTIVNGKGEVVFLDSENSPEVFRAATLSLGKIGIIVKATIRVIPEFNIKSTQEVIHFETLLNNWETIWTSSEFIRCWWYPYTRKVVLWRGSKTEEPLTAPRKSWWGSTFGRFIYESLIWISVKIYPALTPYVESFVFHQQYGRVETYGSGDVSVQTSIAGLNMDCLFSQFVDEWGCPLNNGPEVLRSLDYSITQAAQNKEFFVHVPVEVRCSNTTLPAEIPDYSNRTKTSAGPVFGNTLRPYLDATPRHLRYAPLSDVTNSQLSLYINATIYRPFGSNSPIHKWFTLFEDTMGAAGGKPHWAKNFLGATSMAAGKVKDEKDYDDYEMRGMATKIKEWYGEDLLKFREIRSQQDPNNVFMANKEWAIRNGIIEP
What are the official names of this protein?
D-arabinono-1,4-lactone oxidase, ALO, L-galactono-gamma-lactone oxidase.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
What are the subcellular locations of this protein?
Mitochondrion membrane. Note=Membrane-embedded.
Protein: CINAL_MICAN
Sequence: MAAEIICVGTELLLGDIVNTNAQYLALELAKLGIPHYYQTVVGDNVERLKKAIAIARERSSILIFTGGLGPTPDDLTTETIADFFQTSLREDQEILAEIEAKFTSLGREMPPSNSKQALIPMGADFLPNPTGTAPGMIWQPEANVTILTFPGVPSEMKRMWVETAIPYLESQGWGKERIYSRYLKFRGIGESALAEKVAHLFDLTNPTVAPYASLGEVRLRIATKAPSLEAALQVIEPVATEIKEIAGLDYFGADDDTLPAVVGELLRWQKQTLSVAESCTGGGLGEIITQIAGSSDYFGGGVISYDNRVKVALLDVNEGDLNNFGAVSAIVAQQMALGVQKRLATDWGISITGIAGPGGGSETKPVGLVYIGLASPEGNVTVSEHRFGENRDRLTIRQISAYTALDRLRRNLLIMS
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: RK13_NEOYE
Sequence: MNKTQSPSLNTNSHWYVIDAKNQTLGRISTHISNILRGKNKPSYTPYLDTGDYVIVINSAHVSVSGNKTNQKLYRRHSGQPGGLKVETFDQLQTRLPNRIIEKSVKGMLPKGPLGRKLFTKLKVYSGPIHPHVAQKPQEYIV
What are the official names of this protein?
50S ribosomal protein L13, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.