PharMolix/UniProtQA huggingface dataset:
Protein: SEPF_ACIC1
Sequence: MAFMRKAAVYLGLVEDDEERYEDYDDYDDAEPHRREPREAVERDLGSRRTAVVRRMDARESSPADPAELRRVSEPAPTERPTPPLRVTTLHPRTYNEARAIGEHFREGIPVIMNLTEMDDADAKRLVDFAAGLTFGLRGSIERITSKVFLLSPRNVEVTAEDKRRMAEGGFFNQS
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: SYFA_BURP0
Sequence: MDLDQIVADAQQSFEGAADITTLENEKARFLGKSGALTELLKGLGKLDPETRKTEGARINVAKQQVEAALNARRQALADALLNQRLAAEAIDVTLPGRGAGAGSLHPVMRTWERVEQIFRSIGFDVADGPEIETDWYNFTALNSPENHPARSMQDTFYVDGKDADGRPLLLRTHTSPMQVRYARMNRPPIKVIAPGRTYRVDSDATHSPMFNQVEGLWIDENVSFADLKGVYTDFLKKFFERDDILVRFRPSYFPFTEPSAEIDMMFEHGKNAGKWLEISGSGQVHPTVIRNMGLDPERYIGFAFGSGLERLTMLRYGVQDLRLFFENDLRFLRQFA
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_SINKE
Sequence: MSNQHTLLISNLLPVGSNISTWWNFGSMLLTCLILQITTGFFLAIHYTANINLAFSSVTHIMRDVPYGWIMQNLHAIGASMFFICIYIHIARGLYYGLYMNKNVWLSGTTLLITLMATAFFGYVLPWGQMSFWAATVITNLLTAIPYLGTTITTWLWGGFSINDPTLTRFFALHFILPFAIISLSSIHIILLHNKGSNNPLGTNSDIDKIPFHPYHSYKDTLMTISLFILMFTILSFSPDLFNDPENFSKANPLVTPQHIKPEWYFLFAYGILRSIPNKLGGTLALLMSVTILMTAPFTHTSHMRPMTFRPLAQMAFWTLIATFITITWTASKPVEPPFIIISQMTSILYFLFFIMNPLLGWTENKIMMNN
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: METAA_AGRFC
Sequence: MPIKIPDTLPAFETLVHEGVRVMTETAAIRQDIRPLQIGLLNLMPNKIKTEIQMARLVGASPLQVELSLIRIGGHRAKNTPEEHLLSFYQTWEEVRHRKFDGFIITGAPIELLDYEDVTYWNEMQQIFEWTQTNVHSTLNVCWGAMAAIYHFHGVPKYELKEKAFGVYRHRNLSPSSIYLNGFSDDFQVPVSRWTEVRRADIEKHPELEILMESDEMGVCLAHEKAGNRLYMFNHVEYDSTSLADEYFRDVNSGVPIKLPHDYFPHNDPELAPLNRWRSHAHLFFGNWINEIYQTTPYDPQAIGKLAA
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PALI_CANGA
Sequence: MHLFDLRTLLAILVSICVVFQAFPLATVPLNKNLILGQYMGYHFGVFGWCFVDKGVTIACHCKFRPDSIETYKYTDQLLFPSLYKVTISTLLVVHPVSFAFTCILWIMALIIRLSRFGRCPIFILSAATWSLAAFLLALLSALVDLLLFVNKLKWPGWLVLASVPLMAICCSWLWSLRRQVSAIFYERKAYATQTYSRFDSMELSHIDTKFSDDQSIYETYTLERVPYSKNEAIEEPALTYYTSSS
What is the function of this protein?
Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH.
What are the official names of this protein?
pH-response regulator protein palI/RIM9.
What is the protein family that this protein belongs to?
Belongs to the palI/RIM9 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NU3M_RHISA
Sequence: MIFYLHITIFLVVCLLMMLFFSLGFQGKKAKEKNSPFECGFDPFSLSRVPFSLKFFFVGIVFLIFDVEIVVILPFPLVMMTKNLMFVFSFTFINFLIVLGLLYEFKYSMLDRLK
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 3, NADH dehydrogenase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: MARH5_BOVIN
Sequence: MPDQALQQMLDRSCWVCFATDEDDRTAEWVRPCRCRGSTKWVHQACLQRWVDEKQRGNSTARVACPQCNAEYLIVFPKLGPVVYVLDLADRLISKACPFAAAGIMVGSIYWTAVTYGAVTVMQVVGHKEGLDVMERADPLFLLIGLPTIPVMLILGKMIRWEDYVLRLWRKYSNKLQILNSIFPGIGCPVPRIPAEANPLADHVSATRILCGALVFPTIATIVGKLMFSSVNSNLQRTILGGIAFVAIKGAFKVYFKQQQYLRQAHRKILNYPEQEEA
What is the function of this protein?
Mitochondrial E3 ubiquitin-protein ligase that plays a crucial role in the control of mitochondrial morphology by acting as a positive regulator of mitochondrial fission.  May play a role in the prevention of cell senescence acting as a regulator of mitochondrial quality control.  Promotes ubiquitination of FIS1, DNM1L and MFN1.
What are the official names of this protein?
E3 ubiquitin-protein ligase MARCHF5, Membrane-associated RING finger protein 5, Membrane-associated RING-CH protein V, MARCH-V, RING-type E3 ubiquitin transferase MARCHF5.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein.
Protein: Y434_NITEU
Sequence: MKANLGNLMKQAQQMQENMKAMQEKLAAIEVEGQAGAGMVKVTMTCRYDVKRVNIDSSLIGDDKEMLEDLVAAAVNDAVRRVETVTQEKMASVAGGLGLPAGMKFPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein NE0434.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: TBL27_ARATH
Sequence: MGLNEQQNVPSQRKIIVFIVLAFIPIALFRLCFNNPFSSIKDTSLQDSAANVVITSFSSSSQEEESQESFDHIQDEPLCDYTQGNWVRDEIGPLYNGSTCGTIKDGQNCFRHGRPDSGYLYWKWKPNECDIPRFDSNRFLDLMRDKHLAFIGDSMARNQLESLLCLLSTVSSPDLVYRNGEDNKFRRWRFESHNVTVSVYWSPFLVAGLEKSGNLDHNVLHIDRVDERWGNDLERFDTVVVSVGHWFLHPAVYYESGSVLGCHSCETSNCTEVGFYDVFRKAIRTTLRAVAGSGREVILTTFSPSHFEGRPWDSLGACNMTKPYEGKVLEGLDLDMRKIEIEEYTAAAAEVRLEVLDVTAMSVLRPDGHPGPYMYADPFKNGVPERIPNDCLHWCLPGPVDTWNEIMIEMLRRWKV
What is the function of this protein?
Xyloglucan acetyltransferase that catalyzes the acetylation of fucosylated Gal residues on xyloglucan side chains (PubMed:30083810).  Predominantly catalyze 6-O-monoacetylation of Gal residues in the Fuc-Gal-Xyl trisaccharide side chains of xyloglucan oligomers (PubMed:30083810).  Involved in xyloglucan specific O-acetylation in roots and rosette leaves (PubMed:22086088).
What are the official names of this protein?
Xyloglucan O-acetyltransferase 1, Protein ALTERED XYLOGLUCAN 4, Protein TRICHOME BIREFRINGENCE-LIKE 27.
What is the protein family that this protein belongs to?
Belongs to the PC-esterase family. TBL subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: YO385_YEAST
Sequence: MRGFSGQPLSDDDNYRIEKTQRNTIPERLHFSRERNMPIASIFGTRGYFVFSSEQSYDKFKQTNFNISTLDADGVGVPLFHIVQSYNVIGKITRSSPDFYIYKYVLQGVQDPPLYSDCKVICQDKVFRLCKILYCEIYAHQGFFETKYDFFYPSKTQPVKKYQIIKQSNMRDLYSTLDGMRFRWHVKFYSDHFRLMFLDEDRLNYSNSNQKERQKPDQGKSKAPDFVIGHYTRTFSDILPRSTSKCSNLIIGEHSKPDSLGITTVPDLTQEFACQGALIHYLLHIERERK
What are the official names of this protein?
Uncharacterized protein YOR385W.
Protein: FOLD_STRPN
Sequence: MTQIIDGKALAAKLQGQLAEKTAKLKEETGLVPGLVVILVGDNPASQVYVRNKERSALAAGFRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPKHIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKNAVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLSKVAAKADILVVAIGRAKFVTADFVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQAALRTLDRK
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: LEUD_HAEIE
Sequence: MAGFKQLSGLVVPLDAANVDTDAIIPKQFLQAITRVGFGKHLFHEWRYLDVDGTKPNPEFVLNYPQYQGATILLARKNLGCGSSREHAPWALADYGFKVMIAPSFADIFYNNSLNNHMLPIRLSEEEVEEIFQWVWANESKQIHVDLEAMTVTVGDKVYTFELDEFRRHCLLNGLDNIGLTLQHEDKISAYEKNIPAFLR
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: RLMF_FLAJ1
Sequence: MKAENNSQKDNLHPRNLHRSRYDFELLISNCPELKAFISINKHGIETVDFSNPLAVKTLNKALLQTYYDIQNWDIPKNYLCPPIPGRADYIHYLADLLAETNNGKIPEGNSVMGLDIGTGANLIYPILGNSIYNWSFVATDIYKTSIENASKIIEANPRLIDAVSLQQQTEPRFIFKNIIIPEDRFTFTMCNPPFHASAEEANKSTSRKVSNLNPKEKKNTNPVLNFGGQNAELWCNGGEIGFITQMIYESVKYASQVLWFTTLVSKKENLSSIYKTLKKVNAVSVKTIEMSQGQKNSRIVAWSFLNNTEQKSWKF
What is the function of this protein?
Specifically methylates the adenine in position 1618 of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase F, 23S rRNA mA1618 methyltransferase, rRNA adenine N-6-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL16/RlmF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IDH_RICFE
Sequence: MAEFTPITIAYGDGIGPEIMEAVLYILRKAEARIRLETIEVGEKLYKKHYTSGISEESWESIQRTGIILKAPITTPQGGGYKSLNVTIRKTLQLFANIRPSVSFHPFTMTLHPHLNLTIIRENEEDLYAGIEYRQTHNMYESIKLISHTGCEKIIRYAFEYAVKNNRKKVTCLSKDNIMKFSDGVFHKIFNEIAKEYPQINNEHYIIDIGTARLATKPEIFDVIVTSNLYGDIISDVAAEISGSVGLAGSANIGQHYAMFEAVHGSAPDIAGKDIANPSGLLNAAIMMLVHIGQGDIASLIENAWKKTIEDGVHTADIYNEQNSSKKVGTKEFAEEVTKRLGQIPTKLPKADYPLIAEKQESNIDYKIDTNEVKKLVGTDIFVNMNISSAHDIADKINKLDLGNIELKTISSKGLKLWPRDTRFETISDHWCCRFMNKDGTEIKHLDITRLLEALSKANIDFIKVENLFEFDGVAGYSLAQGE
What are the official names of this protein?
Isocitrate dehydrogenase [NADP], IDH, IDP, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
Protein: TPS28_TRIWF
Sequence: MFMSSSSSSHARRPQLSSFSYLHPPLPFPGLSFFNTRDKRVNFDSTRIICIAKSKPARTTPEYSDVLQTGLPLIVEDDIQEQEEPLEVSLENQIRQGVDIVKSMLGSMEDGETSISAYDTAWVALVENIHHPGSPQFPSSLQWIANNQLPDGSWGDPDVFLAHDRLINTLACVIALKKWNIHPHKCKRGLSFVKENISKLEKENEEHMLIGFEIAFPSLLEMAKKLGIEIPDDSPALQDIYTKRDLKLTRIPKDIMHNVPTTLLYSLEGLPSLDWEKLVKLQCTDGSFLFSPSSTAFALMHTKDGNCFSYINNLVHKFNGGVPTVYPVDLFEHIWCVDRLQRLGISRFFHPEIKECLGYVHRYWTKDGICWARNSRVQDIDDTAMGFRLLRLHGYEVSPDVFKQFRKGDEFVCFMGQSNQAITGIYNLYRASQMMFPEETILEEAKKFSVNFLREKRAASELLDKWIITKDLPGEVGFALDVPWYACLPRVETRLYIEQYGGQDDVWIGKTLYRMPYVNNNVYLELAKLDYNNCQSLHRIEWDNIQKWYEGYNLGGFGVNKRSLLRTYFLATSNIFEPERSVERLTWAKTVILVQAIASYFENSREERIEFANEFQKFLNTRGYINGRRLDVKQATKGLIEMVFATLNQFSLDALVVHGEDITHHLYQSWEKWVLTWQEGGDRREGEAELLVQTINLMAGHTHSQEEELYERLFKLTNTVCHQLGHYHHLNKDKQPQQVEDNGGYNNSNPESISKLQIESDMRELVQLVLNSSDGMDSNIKQTFLTVTKSFYYTAFTHPGTVNYHIAKVLFERVV
What is the function of this protein?
Diterpene synthase that catalyzes the formation of (-)-kolavenyl diphosphate from geranylgeranyl diphosphate (GGPP).
What are the official names of this protein?
(-)-kolavenyl diphosphate synthase TPS28, chloroplastic, Terpene synthase 28, TwTPS28.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsc subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ATP8_PANPA
Sequence: MPQLNTAVWPTTITPMLLTLFLITQLKMLNSNYHLPPSPKPMKMKNYNKPWEPKWTKICSLHSLPPQS
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: SYR_MARSD
Sequence: MKAKQHLENVLGSILEAKGWEWPEKAVIEPPKDKKFGDMSANIAMMLSKQAKMNPRAIAETIQSELDGDKYIEKVDIAGPGFLNFTFSNSFWQDLIPEVLTKGEDYGRSEIGKDTKIQVEYVSANPTGPLHIGHGRGAALGDCLVRILEFTGYDVEAEYYVNDAGRQMLILGTSIWVRLQQSQGRDIADPEDFYKGEYIKDLAAEVLERNPGILDMSDDEAIAICREYGKDEILEGIKKDLAAFDVRHDVWFSEKSLVTANKVEETFADLKARGMAYEEDGALWFKSTELGDDKDRVLRKSNGDLTYFASDIAYHDDKYKRGFDIVVDIWGADHHGYIPRMQAAVEALGKKGQLDVILVQLVNLLRGGEQIAMSTRAGKFETLEDVVNEVGRDASRFMFLSRKSDSHLDFDLELVKQKTMDNPVYYVQYAHARICSVMRKAADQGIAVPAIDAAPLSALTNAEELNLMKLMDQFADVAENAGKNMSPHVISYYLRDLASALHRFYSMHHILSADEDVIAARLVLLQAVARTLANGLSLLGVSAPESM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMO_BURMS
Sequence: MENSLKSSGKPLAAPKVGMVSLGCPKALVDSEQIITQLRAEGYEISGTYDGADLVVVNTCGFIDEAVQESLDAIGEALAENGKVIVTGCLGAKKSASGSGLIAEVHPKVLAVTGPHAVGEVMQAVHSHLPKPHDPFVDLVPAAGIKLTPRHYAYLKISEGCNHRCSFCIIPSMRGELVSRPVAEVMLEAENLFKSGVKELLVISQDTSAYGVDVKYRTGFWNGRPLKTRMTELVGALGELAAQYGAWVRLHYVYPYPHVDEIIPMMAQGPLKGHVLPYLDVPFQHAHPEVLKRMKRLANAERVLERVQKWREICPDLTIRSTFIAGFPGETDAQFETLLDFIREAELDRVGCFAYSPVEGASANALDGALPDDVREARRARFMEVAEEVSAARIARKIGKTLKVLIDEVNAEGGIGRTAADAPEIDGVVYVEPAAKASKRYKVGEFVSVKITGADGHDLWGEV
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S1PNA_SULTO
Sequence: MKAFILAAGSGERLEPITHTRPKAFVPILSKPLIEYQIEYLRKCGIRDITVIVSSKNKEYFEKKLKEISIVTQKDDIKGTGAAILSAKFNDEALIIYGDLFFSNEKEICNIITLKENAIIGVKVSNPKDYGVLVLDNQNNLSKIIEKPEIPPSNLINAGIYKLNSDIFTYLDKISISERGELELTDAINLMAKDHRVKVIEYEGYWMDIGKPWNIIDVNKWALDNLVFSQNLGNVEDNVKIKGKVIIEEDAEIKSGTYIEGPVYIGKGSEIGPNSYLRPYTILVEKNKIGASVEVKESVIMEGSKIPHLSYVGDSVIAEDVNFGAGTLIANLRFDEKEVKVNVKGKRISSGRRKLGAFIGGHVRTGINVTILPGVKIGAYARIYPGAVVNRDVGYGEFFKV
What is the function of this protein?
Bifunctional enzyme involved in the synthesis of UDP-N-acetylglucosamine (UDP-GlcNAc) and UDP-N-acetylgalactosamine (UDP-GalNAc).  It has multiple amino-sugar-1-phosphate acetyltransferase activities, including glucosamine-1-phosphate (GlcN-1-P) acetyltransferase and galactosamine-1-phosphate (GalN-1-P) acetyltransferase activities, and multiple sugar-1-phosphate nucleotidylyltransferase activities, including N-acetylglucosamine-1-phosphate (GlcNAc-1-P) uridyltransferase and N-acetylgalactosamine-1-phosphate (GalNAc-1-P) uridyltransferase activities (PubMed:15598657, PubMed:20400541, PubMed:25567746).  Also catalyzes the formation of dTDP-glucose from dTTP and glucose-1-phosphate (Glc-1-P), and the reverse reaction, which produces dTTP from dTDP-glucose and diphosphate (PubMed:15598657).  Can also catalyze the formation of UDP-glucose from UTP and glucose-1-phosphate (PubMed:27864169, PubMed:30291121).
What are the official names of this protein?
Bifunctional sugar-1-phosphate nucleotidylyltransferase/acetyltransferase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
Protein: GLME_HALMA
Sequence: MPTDERLSDDQLQRIANDLRDNWHTGREVDFEEAIAFHESLPASKQFAQVLESADQPLLQPRAGVPCLEEQIDLLRYLQDEGGADLLPTTIDSYTRDNEYEKAEEGLAASRGSDENELNGFPAVNHGVEDCRRLIRALDAPVEVRHGTPDARLLAMVTLAGGFQSFEGGPISYNIPYTKRHDLATTIEHWQFVDRLCGAYTERGVTINREPFGPLTGTLVPPSIAIAVMLVEGELAATQGVRSLTLGYGQVGNLVQDVAALRALRKLGNEYLRDEVTVTTVFHEWMGGFPPDEARANGVISLGGATAAVAQPDKVITKSAQEFQGVPTKEANAAGLRTTRQLIDMMIEQDIDLGGIDEEQALIERETRALMDAIYEAGDGDVAQGVINAFDSGALDVPFAPSDAAKGAVLPARDDDGRVRIFEFADLALPDDIKEIHAARLGERAETEGRDQSFRMVADDVDAISDGKLIGRPGGDNSPAGGASDAD
What is the function of this protein?
Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
What are the official names of this protein?
Glutamate mutase epsilon subunit, Glutamate mutase E chain, Glutamate mutase large subunit, Methylaspartate mutase.
What is the protein family that this protein belongs to?
Belongs to the methylaspartate mutase GlmE subunit family.
Protein: PEX25_YEAST
Sequence: MSQFGTTDIVSGSETPPYSGASYQDAQDDNTHPHSSDAGAEKFSAGSGSESHTESSRSDDEDSQAKTKMVDNITILKYILDSLSGRDKLAKIIKYALDILKLFIEKSKRNLTVLDPSVLTYYTKILKNLTVKVALRHPITVIKVLLLSLLRNFDKKIDFISQQLSTFRYILRFGGTPFRVCSFLGKFNKTRKCNFQIDQIKKIWFNEASLREFLDLYYGIFDELDLLYKLKIWTNKSFYSFVSRQESLAWQYDILLSLKDHWLNLQSLQKRQLELEVQLKVQNNALLLSPILMHQAHKDDGSQSPIRKQLLNDLNVNNDAEVLIHKQLKAIKDEKTLVYLDIARLSFDCMANTSDILNLKTPKGTYAVLSLGSGLTGLVKLWITTKRSLCSSKD
What is the function of this protein?
Required for regulation of peroxisome size and maintenance.  Has a role in the import of peroxisomal matrix proteins.  Imports RHO1 into the peroxisome.  Also promotes peroxisome division and biogenesis.
What are the official names of this protein?
Peroxisomal membrane protein PEX25, Peroxin-25.
What are the subcellular locations of this protein?
Peroxisome membrane; Single-pass membrane protein.
Protein: CALM3_SOLTU
Sequence: GCITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLNLMARKIKDTDFEEELKEAFRVFDKDRNGFISAAELPHVMTNLGEKLTDEEVDEIIREADVDCDGQINYDEFVKVMMAK
What is the function of this protein?
Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+).  Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
What are the official names of this protein?
Putative calmodulin-3, CaM-3.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
Protein: COX2_SYMSY
Sequence: MAHAAQMGLQDATSPIMEELISFHDHALMIIFLISFLVLYALFLTLTTKLTNTNITDAQEMETVWTILPAIILVLIALPSLRILYLTDEINDPSFTIKAIGHQWYWAYEYTDYGGLIFNSYMLPPLFLEPGDLRLLEVDNRVVLPIEAPVRMMITSQDVLHSWTVPSLGLKTDAIPGRLNQTTFTATRPGVYYGQCSEICGANHSFMPIVLELIPLKIFEMGPVFTL
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: HSM3_CANAL
Sequence: MLDELSYKVLTNLETSYERKQPLGSKLIDRYTLTIDQSTVAQQSYFEQIIPAINRILMNSEAHVIDPDNVLIRLLPEILSHLSFEQILMYYPNDFILHFLFEEKLENVSVICLEVILLNLQEPETLQFLRDNNVISRLLREVYFKKTPISVLNKIERLITVLNGIEEINLLESCLPILKKIRDQGNTVLLSRYLDLVNLLLRYLPEFSPHLYSFTKQEFLKYQDDPLFLILLIQFYVKLVRLKAPVDLSLPLSDILSLYDKFDLLVKNEVVELVAQLSFTQSYTDILFKSQIFKTHNLLEVFEKTENSDIRLLSKANPQVIYELNNSIYPDVLAHLNLFTNNLYFPILLNFMSSTTIFYQLKLHLNNEKLSQLPMDKLFKLLLEMSTHNHSKEHLFNNLPTIMSTNLLETEDLRNNELWNLKLEILQNLLNDDSVPGFEFWHQELTRNYELMTFGRVFRNAAPRVDIIDETA
What is the function of this protein?
Involved in DNA mismatch repair in slow-growing cells.  Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the 19S regulatory complex (RC) (By similarity).
What are the official names of this protein?
DNA mismatch repair protein HSM3.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S5B/HSM3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_BRUO2
Sequence: MSIDSLPPLREVIERHDLMPKKSLGQNFLFDLNLTSKIARQAGDLRDQPVIEVGPGPGGLTRALLAQGAYVTAIERDDRCLEALAEIAAHYPGRLRIIAGDALEQDFTALFPEGPKPRIVANLPYNVGTQLLLNWLLVEPWPPFYSSMTLMFQREVAERIVAKPDSDHYGRLGVLAGWRTQAKIAFDVPPQAFTPPPKVMSSVVHIVPRETPLPCRAEALGQITQAAFGQRRKMLRQSLKSIGGAALLEKTGIDGTRRAETLSVEEFVALANACLP
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEC65_CANAX
Sequence: MSNNKRPVLEEVDDDDIDNMDMDIAEFDPSLTTPIAPKRPEPTVVRSQDSEPSLFPNIPSNQVQPPPKQASSRNGIMDPNSFTEEEKKQFDQFQIIYPCYFDINRSHKQGRRVSIDRAVENPLATTISDACRRLGLPVFLELDKTHPQDFGNPGRVKVLFKAVFDNGKLINPKLQTKRVLFNVIAEYLSEHPTTLESIGPKSGVPRPPEFENDFQPEEIPKVKGFKMNTIVPIHSNLTLKHPMTKHIYDPEPETPAAGKPNVPKIPKKKVMKIRG
What is the function of this protein?
Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane.  It must be involved intimately in the translocation of a wide variety of protein substrates (By similarity).
What are the official names of this protein?
Signal recognition particle SEC65 subunit.
What is the protein family that this protein belongs to?
Belongs to the SRP19 family.
What are the subcellular locations of this protein?
Cytoplasm.