PharMolix/UniProtQA huggingface dataset:
Protein: DAPF_BACMK
Sequence: MSQFSFTKMHGLGNSYIYVNMFEEQIREEDLAIVAEKVSNINTGIGADGMILICPSDVAPVKMRMFNNDGSEGKSCGNGLRCVAKYAYEHKLVEGKVFTIETLAGIVTAEVTVEDDKVTLAKIDMGAPRLTREEIPMLGEGETPFIRENFLYNNHRYAFTAVSMGNPHAVIFVDDVENAPLTTLGPVLETHEMFPERVNVEFIEILNDEEMNFRVWERGSGVTQACGTGACAAVVAAILNGKMEHGKEITVHLAGGDLMIAWTEEGNVLMKGPAEIICRGVYEYKIEA
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA_LACJO
Sequence: MKQMIIHGGKPLKGDVWIGGAKNSTVALIPASILSRTPVTLEGVPRIADVDNLMDLLSEMDVKCDFHETTLRINPDNIKRSPLPAGKIKSLRASYYFMGALLGRFGKAVVGFPGGDDIGPRPIDQHIKGFEALGATVENKNDQIIITAPKTGLRGAKIHLKMPSVGATMNIIMASVMAKGQTIIENAAKEPEIIDLATFLNNMGAVIRGAGTEVIRIEGVEELKAQTPHTIIPDRIEAGTYVALAACIGNGIRIHNIIEEHLDSYLAKVEEMGVVIDADEDSLYVYPAGDLKMIQVRTDVYPGFATDLQQPITPLLLTAKSGEGVVIDQIYPKRVGHIPELQKMGANIQVEDNIILVHPTHHLHGAHVSAGEIRAGACLMLAGLMADGETIISNAGNILRGYDRIEQKLRQLGAEVSVIDV
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OSH3_YEAST
Sequence: METIDIQNRSFVVRWVKCGRGDVINYQIKPLKKSIEVGIYKKLKSSVDDHASAVHIAPDTKTLLDYTTKSLLHKGSSSNIEEHHRRSSQHSHSSSNGSDNKRKERSYSSLSISGIQQQSQEIPLREKLSASGFTLVKRVGNVSGNTMVQGDLEVKDTDYYYAFILDNSSSKNAKKKILFNASVINGDNQSMISTRSTPPARPTALSRTSTQQDMLFRVGQGRYLQGYLLKKRRKRLQGFKKRFFTLDFRYGTLSYYLNDHNQTCRGEIVISLSSVSANKKDKIIIIDSGMEVWVLKATTKENWQSWVDALQTCFDDQFEDKDTSTLEENPDILDDDKEVINKSSPQDHDHLTPTATTKSALSHRQHTQKDMDDIYVPLPSESYATFSMNLRLIQQRLEQCKKDSLSYKPTTLHQRSEGLNGTHSSSSVFTNNRVSSFNHSSSGMTSSDSLASEEVPSNKTYIEHALYNQLADLEVFVSRFVTQGEVLFKDHQILCKKAKDTRVSLTSYLSENDEFFDAEEEISRGVIILPDTEDDINNIVEETPLLGKSDQNEFTKEVQLSGSEQIASSSVESYTTNDENHSRKHLKNRHKNRRRGHPHHQKTKSAQSSTETFTSKDLFALSYPKSVTRRNDIPEAAASPPSLLSFLRKNVGKDLSSIAMPVTSNEPISILQLISETFEYAPLLTKATQRPDPITFVSAFAISFLSIYRDKTRTLRKPFNPLLAETFELIREDMGFRLISEKVSHRPPVFAFFAEHLDWECSYTVTPSQKFWGKSIELNNEGILRLKFKTTGELFEWTQPTTILKNLIAGERYMEPVNEFEVHSSKGDKSHILFDKAGMFSGRSEGFKVSIIPPPSSNRKKETLAGKWTQSLANETTHETIWEVGDLVSNPKKKYGFTKFTANLNEITEIEKGNLPPTDSRLRPDIRAYEEGNVDKAEEWKLKLEQLQRERRNKGQDVEPKYFEKVSKNEWKYITGPKSYWERRKKHDWSDISQLW
What is the function of this protein?
Lipid transport protein (LTP) involved in non-vesicular transfer of lipids between membranes.  Functions in phosphoinositide-coupled directional transport of various lipids by carrying the lipid molecule in a hydrophobic pocket and transferring it between membranes through the cytosol.  Involved in maintenance of intracellular sterol distribution and homeostasis (PubMed:11238399, PubMed:15173322).  May serve as a sensor of PI4P levels at PM-ER membrane contact site, regulating PI4P phosphatase SAC1 activity (PubMed:21295699).  May be involved in ergosterol transport from the plasma membrane (PM) to the ER, however it does not bind sterols directly (PubMed:16585271, PubMed:23791945).  Plays a role in the positive regulation of vesicular transport of ceramide from the ER to the Golgi, negatively regulating COPII-mediated ER export of cargos (PubMed:24213531).
What are the official names of this protein?
Oxysterol-binding protein homolog 3, Oxysterol-binding protein-related protein 3, ORP 3, OSBP-related protein 3.
What is the protein family that this protein belongs to?
Belongs to the OSBP family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum membrane. Note=Enriched at the cell periphery in a SCS2-dependent manner (PubMed:12727870). Enriched on regions of the ER in close proximity with the plasma membrane (PM), which may represent PM-ER membrane contact sites (MCS) (PubMed:20008566). Localizes to PM-ER membrane contact sites dependent upon PM PI4P levels (PubMed:21295699).
Protein: RNP3_METTH
Sequence: MIPQRILMKFFDFHIQGRDHDSSLRLLLEASRLGYQGGVLVYPSERYPDLKSDLESLRENPELQDFEIARGVMINASDPRDMRRSVNKFRKKADVIYVSGGNLKVNRAACESRRVDVLSAPYTSRRDPGINHVLAREAARNNVAVELPLADVIGSWLKVRARVLEQFREILKLHRKFGFPLLLTSRASSIYDLRTPGDIMNLAECFGMESSEAEESLTSTPASILEDSGNRHLLIAEGVRLLPES
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 3, RNase P component 3, Rpp30.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_THEPX
Sequence: MISAQAVKELRERTGAGMMDCKKALMEANGDMEKAIDILREKGLAAAAKKAGRVANEGLVDAYIHSGGRIGVLVEVNCETDFVANTDEFKNFVKEICMQIAAANPKYISREDVPQAVLEKEREILKAQALNEGKPQNVVDRIVEGRIEKFYKENCLLEQEYIRDPEKTVKDLLNETIAKLGENIVIRRFVRFERGEGIETSSNE
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_SALSV
Sequence: MQVSVETTQGLGRRVTITIAADSIETAVKSELVNVAKKVRIDGFRKGKVPMNIVAQRYGASVRQDVLGDLMSRNFVDAIIKEKINPAGAPNYVPGEYKVGEDFTYSVEFEVYPEVELTGLESIEVEKPVVEVTDADVDVMLDTLRKQQATWKEKDGAADAEDRVTIDFTGSVDGEEFEGGKATDFVLAMGQGRMIPGFEDGVKGHKAGEEFTIDVTFPEEYHAENLKGKAAKFVINLKKVEERELPELTEEFIKRFGVEDGSVAGLRAEVRKNMERELKGAVRNRVKSQAIEGLVKANDIDVPAALIDSEIDVLRRQAAQRFGGNEKQALELPRELFEEQAKRRVVVGLLLGEVIRTNELKADEERVKGLIEEMASAYEDPKEVIEFYSKNKELMDNMRNVALEEQAVEAVLAKAKVSEKATSFNELMNQQA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: IF6_OSTLU
Sequence: MAARHQFENSNEIGVFAALTNAYCLAAVGGSENFYSVFEAELSNEIPVIKASLAGTRLVGRLSVGNKHGLLLPTSATDQEVMHIRNSLPDEVIVQRTEERLSALGNCVACNDHVALVHPDIDQETEEIIADVLGVEVFRQSVAGNVLVGSFCKFSNRGGMVHPQASVQEVDELSSLLQVPLVAGTINRGSDVIGAGLLVNDWIAFCGLDTTSTEIQVIESIYQLHGADSSGAVRDIRASLLDTLV
What is the function of this protein?
Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm.  May also be involved in ribosome biogenesis.
What are the official names of this protein?
Eukaryotic translation initiation factor 6, eIF-6.
What is the protein family that this protein belongs to?
Belongs to the eIF-6 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Note=Shuttles between cytoplasm and nucleus/nucleolus.
Protein: RPPH_HAES1
Sequence: MIDFDGYRPNVGIVICNAERQVLWAKRYGQNSWQFPQGGINDNETAEQAMYRELYEEAGLTPKDVEILYVSKHWLRYKLPKRLLRHDNRPICIGQKQRWFLLQLVSDEKRINMQHTKSPEFDGWRWVSFWYPVRQVVTFKKDVYRKVMKEFALFLFDTNLKSRLSVPEEKKMFSSVKKKLIHKKNHKYSSNQ
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: CAPSD_HBVG1
Sequence: MDRTTLPYGLFGLDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTASALYRESLESSDHCSPHHTALRQAILCWVELMTLATWVGNNLEDPASRDLVVNYVNTNMGLKIRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRGRSPRRRTPSPRRRRSPSPRRRRSQSRESQC
What is the function of this protein?
Self assembles to form an icosahedral capsid.  Most capsids appear to be large particles with an icosahedral symmetry of T=4 and consist of 240 copies of capsid protein, though a fraction forms smaller T=3 particles consisting of 180 capsid proteins.  Entering capsids are transported along microtubules to the nucleus.  Phosphorylation of the capsid is thought to induce exposure of nuclear localization signal in the C-terminal portion of the capsid protein that allows binding to the nuclear pore complex via the importin (karyopherin-) alpha and beta.  Capsids are imported in intact form through the nuclear pore into the nuclear basket, where it probably binds NUP153.  Only capsids that contain the mature viral genome can release the viral DNA and capsid protein into the nucleoplasm.  Immature capsids get stuck in the basket.  Capsids encapsulate the pre-genomic RNA and the P protein.  Pre-genomic RNA is reverse-transcribed into DNA while the capsid is still in the cytoplasm.  The capsid can then either be directed to the nucleus, providing more genomes for transcription, or bud through the endoplasmic reticulum to provide new virions.
What are the official names of this protein?
Capsid protein, Core antigen, Core protein, HBcAg, p21.5.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus core antigen family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: YJ77A_YEAST
Sequence: MPGIAFKGKDMVKAIQFLEIVVPCHCTT
What are the official names of this protein?
Uncharacterized protein YJL077W-A.
Protein: CDCP2_MOUSE
Sequence: MLAELGACLLLAMVLLDSDPGTQAMEGVKCGGVLSAPSGNFSSPNFPSLYPYNTECSWLIVVAEGSSVLLTFHAFDLEYHDTCGFDFLEIYNGASGDKGNLLGRFCGQVPPPPFTSSWHVMSVVFHSDKHVASRGFSAGYQKDVCGGVLTGLSGVLSSPEYPNNYPNNVECHWLIRASGPAAVKLVFVDFQVEGSDECMYDYVAVLGAPGPAHGHHYCGRTRPPTFVSLGHELQVVFKSDFNIGGRGFKAHYFSGECQEVFTAVRGNFSSPQYPGAYPNNIRCHWTIRLPPGYRVKVFILDLGLEEPNSLTRTCDFDHLAAFDGASEEAQLLGKWCGHHLPPPVTSSRNQVLLLLHTDRSTSGRGFSVAYIGGQLGVCPWELCGPFLCPLRHSPSTDSSRPHSVAYPGDLGGHSSTALIYFHCHLFS
What are the official names of this protein?
CUB domain-containing protein 2.
What are the subcellular locations of this protein?
Secreted.
Protein: HUTH_BACSU
Sequence: MVTLDGSSLTTADVARVLFDFEEAAASEESMERVKKSRAAVERIVRDEKTIYGINTGFGKFSDVLIQKEDSAALQLNLILSHACGVGDPFPECVSRAMLLLRANALLKGFSGVRAELIEQLLAFLNKRVHPVIPQQGSLGASGDLAPLSHLALALIGQGEVFFEGERMPAMTGLKKAGIQPVTLTSKEGLALINGTQAMTAMGVVAYIEAEKLAYQTERIASLTIEGLQGIIDAFDEDIHLARGYQEQIDVAERIRFYLSDSGLTTSQGELRVQDAYSLRCIPQVHGATWQTLGYVKEKLEIEMNAATDNPLIFNDGDKVISGGNFHGQPIAFAMDFLKIAISELANIAERRIERLVNPQLNDLPPFLSPHPGLQSGAMIMQYAAASLVSENKTLAHPASVDSIPSSANQEDHVSMGTIAARHAYQVIANTRRVIAIEAICALQAVEYRGIEHAASYTKQLFQEMRKVVPSIQQDRVFSYDIERLTDWLKKESLIPDHQNKELRGMNI
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MPGP_ECOUT
Sequence: MLSIQQPLLVFSDLDGTLLDSHSYDWQPAAPWLSRLREANVPVILCSSKTSAEMLYLQKTLGLQGLPLIAENGAVIQLAEQWQDIDGFPRIISGISHGEISQVLNTLREKEHFKFTTFDDVDDATIAEWTGLSRSQAALTQLHEASVTLIWRDSDERMAQFTARLNELGLQFMQGARFWHVLDASAGKDQAANWIIATYQQSSGKRPTTLGLGDGPNDAPLLEVMDYAVIVKGLNREGVHLHDEDPTRVWRTQREGPEGWREGLDHFFSAR
What are the official names of this protein?
Mannosyl-3-phosphoglycerate phosphatase, MPGP.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MPGP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANG3_MOUSE
Sequence: MVMSPGSLLLVFLLSLDVIPPTLAQDNYRYIKFLTQHYDAKPTGRDYRYCESMMKKRKLTSPCKEVNTFIHDTKNNIKAICGENGRPYGVNFRISNSRFQVTTCTHKGGSPRPPCQYNAFKDFRYIVIACEDGWPVHFDESFISP
What is the function of this protein?
May promote vascularization of normal and malignant tissues (By similarity).  Has low ribonuclease activity (in vitro).
What are the official names of this protein?
Angiogenin-3, Angiogenin-related protein 2, EF-5.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle lumen. Secreted. Nucleus, nucleolus. Note=Rapidly endocytosed by target cells and translocated to the nucleus where it accumulates in the nucleolus and binds to DNA (By similarity).
Protein: KAS2_STRCO
Sequence: MSGPQRTGTGGGSRRAVVTGLGVLSPHGTGVEAHWKAVADGTSSLGPVTREGCAHLPLRVAGEVHGFDAAETVEDRFLVQTDRFTHFALSATQHALADARFGRADVDSPYSVGVVTAAGSGGGEFGQRELQNLWGHGSRHVGPYQSIAWFYAASTGQVSIRNDFKGPCGVVAADEAGGLDALAHAALAVRNGTDTVVCGATEAPLAPYSIVCQLGYPELSRATEPDRAYRPFTEAACGFAPAEGGAVLVVEEEAAARERGADVRATVAGHAATFTGAGRWAESREGLARAIQGALAEAGCRPEEVDVVFADALGVPEADRAEALALADALGPHAARVPVTAPKTGTGRAYCAAPVLDVATAVLAMEHGLIPPTPHVLDVCHDLDLVTGRARPAEPRTALVLARGLMGSNSALVLRRGAVPPEGR
What is the function of this protein?
Involved in developmentally regulated synthesis of a compound biosynthetically related to polyketide antibiotics which is essential for spore color in Streptomyces coelicolor.
What are the official names of this protein?
Putative polyketide beta-ketoacyl synthase 2, WhiE ORF IV.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
Protein: FMT_PROM2
Sequence: MRIIFWGTPDYSISSLDILIKSNHEIIAVVSQPDKKRSRGNKLIASPIKSFAEQEYIKIYTPEKIRNNIPFINELKSLSCDLFIVIAYGKILPKEILEIPKFGCWNAHASLLPRWRGAAPIQWSLMKGDEYTGVGIMKMSEGLDTGDLLLEEKIKIDNTDNLNTLTEKLSILSAKLLLKAVSFLEKNINKKINSKLTKQNTLGREITYARMIEKSDFKVDWGNEAIKISRKIKALYPRANTNFRGKNLKILKIKVLTSDEIKNAKYHLMSNYSKPGIILAVIENEGIIISTKTDPIILLEAKIEGKNISTKKQLIQQLKPSVGEYFLD
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: NSP3_ROTAD
Sequence: MESTQQMVSSIINTSFEAAVVAATSTLELMGIQYDYNEVFTRVKSKFDYVMDDSGVKNNLLGKAITIDQALNGKFGSAIRNRNWMTDSKTVAKLDEDVNKLRMTLSSKGIDQKMRVLNACFSVKRIPGKSSSIIKCTRLMKDKIERGEVEVDDSYVDEKMEIDTIDWKSRYDQLEKRFEALKQRVNEKYNTWVQKAKKVNENMYSLQNVISQQQNQIADLQQYCNKLEADLQGKFSSLVSSVEWYLRSMELPDDVKNDIEQQLNSIDLINPINAIDDIESLIRNLIQDYDRTFLMLKGLLKQCNYEYACE
What is the function of this protein?
Plays an important role in stimulating the translation of viral mRNAs.  These mRNAs are capped but not polyadenylated, instead terminating in a conserved sequence 'GACC' at the 3' that is recognized by NSP3, which competes with host PABPC1 for EIF4G1 binding.  The interaction between NSP3 and host EIF4G1 stabilizes the EIF4E-EIF4G1 interaction, thereby facilitating the initiation of capped mRNA translation.
What are the official names of this protein?
Non-structural protein 3, NSP3, NCVP4, Non-structural RNA-binding protein 34, NS34.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP3 family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: MURC_FLAPJ
Sequence: MNLNQIHNVYFIGIGGIGMSALARYFKFIGKNVSGYDKTPSILTSELIESGIAIHFEDNIDLIPKDYFVENTLVIITPAVPKSHSEWNYFLEREYHVKKRAEVLGIITKDTFCLAVAGTHGKTTTSSILGHILYESGADVTAFIGGIVENYNSNLIGSGKTVTVVEADEFDRSFLHLYPNIACVTSMDADHLDIYGDDAAIKASFKEFADKVEDKNKLFVINGLPLKGITVGANDDSQFVAHNIRIENGWYIFDVKTPTENIKDLKFGLPGKHNLTNALLALAMARTFGTPTESIAKALASFKGVKRRFSFQIRKPKFVYIDDYAHHPTEINAVHQAVRELYPNEKVLAVFQPHLFSRTKDFANDFAKSLSQFDEILLLDIYPARELPIEGINSGWLLDKVENKNKKLVHKNELIPLLKKSDATVIVTIGAGDIGEMVVNIKKELDEK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_SALNS
Sequence: MARHPRWTLSQVTELFEKPLLELLFEAQQIHRQHFDPQQVQVSTLLSIKTGACPEDCKYCPQSSRYKTGLEAERLMEVEQVLDSARKAKNAGSTRFCMGAAWRNPHERDMPYLEKIVQGVKAMGLETCMTLGMLNESQAQRLANAGLDYYNHNLDTSPEFYGNIITTRTYQERLDTLEKVREAGIKVCSGGIVGLGETVTDRAGLLLQLANLPTPPESVPINMLVKVKGTPLADNDDVDAFDFIRTIAVARIMMPTSYVRLSAGREQMNEQTQAMCFMAGANSIFYGCKLLTTPNPAEDKDLQLFRKLGLNPQQTRVLAGDNEQQQRLEQTLMTPDTDDYYNAAAL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: IF3_STAA8
Sequence: MSTIAKDQTQINDKIRAKELRLIGQDGEQIGVKSKREALKMAERVDLDLVVVAPNAKPPVARIMDYGKFKFEQQKKEKEMKKKQKIINVKEIRLSPTIEEHDFQTKLKNGRKFLTKGDKCKVSIRFRGRAITHKEIGQRVLEKYADECKDIATVEQKPKMDGRQMFIMLAPTAEK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GHRA_SALTY
Sequence: MEIIFYHPTFNAAWWVNALEKALPHARVREWKVGDNNPADYALVWQPPVEMLAGRRLKAVFVLGAGVDAILSKLNAHPEMLDASIPLFRLEDTGMGLQMQEYAVSQVLHWFRRFDDYQALKNQALWKPLPEYTREEFSVGIMGAGVLGAKVAESLQAWGFPLRCWSRSRKSWPGVESYVGREELRAFLNQTRVLINLLPNTAQTVGIINSELLDQLPDGAYVLNLARGVHVQEADLLAALDSGKLKGAMLDVFSQEPLPQESPLWRHPRVAMTPHIAAVTRPAEAIDYISRTITQLEKGEPVTGQVDRARGY
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
What are the official names of this protein?
Glyoxylate/hydroxypyruvate reductase A, 2-ketoacid reductase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBT_PROM9
Sequence: MEAFAYVLILTLAVVTLFFAVAFRDPPKFDRK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: 11012_ASFM2
Sequence: MKVFLGLLLGYSTILILTYQSPTTQHPPKEELEYWCTYAKTCDFCWDCQNDTCINKVINESISMNSIVNCRVTRDSQSQSCFYEISLKIPNYHSMECSYPRLYKHFMSMEKWRDENWPILIRHYCFYLVFSFAFAGCVAFAICKNLRLRTTMKLLMLLSILVLLSQPILNN
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 110-12L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 110 family.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: HIS8_BACFR
Sequence: MKTLQELTRPNIWRLKPYSSARDEYSGAAASVFLDANENPYNLPHNRYPDPMQRDLKLELSKIKKVAPAHIFLGNGSDEAIDLVFRAFCEPGRDNVVAIDPTYGMYQVCADVNDVEYRKVLLHDDFQFSADELLAVADERTKMIFLCSPNNPTGNDLLRSEIIKVINDFEGLVILDEAYNDFSDEPSFLSELDKYPNLIILQTFSKAFGCAAIRLGMAFASEGIIGVLNKIKYPYNVNQLTQQQAIEMLHKYYEIERWVKTLKEERGYLEEAFVELPWVLQVFPSNANFFLARVTDAVKIYNYLVGEGIIVRNRNSISLCGNCLRVTVGTRAENAKLIGALKKYQ
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: SYH2_BACCZ
Sequence: MSIQIPRGTQDILPGTVELWQYIEGQAREICRRYNYKEIRTPIFEHTELFLRGVGDTTDIVQKEMYSFQDRGERSLTLRPEGTAPVVRSYVENKMFGDATQPTKLYYIGQMFRYERPQAGRYRQFVQFGIEAIGSNDPAIDAEVIALAVEFYRGMGLKNIKVVLNSLGDAASRQAHRDALIAHFEPRIGEFCSDCQSRLEKNPLRILDCKKDRNHELMGTAPSITEYLNEDSAVYYDKVQELLTMMDVPFEKDPNLVRGLDYYQHTVFEIMSEAEGFGAITTLSGGGRYNGLVQEIGGPEMPGIGFAMSIERLIMALKAENIELPIEHSIDCYVVALGEKAKDHAAKVAFDLRKAGLAVEKDYLDRKMKAQFKSADRLKAKFVAVLGEDELDKGIINLKDMATGEQEEVALDVFASYVAEKLI
What are the official names of this protein?
Histidine--tRNA ligase 2, Histidyl-tRNA synthetase 2, HisRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CT5B_CONAL
Sequence: FCCPVIRYCCW
What is the function of this protein?
Causes dorsal fins drooping in fish.  No effect is observed when injected into mice (By similarity).
What are the official names of this protein?
Conotoxin au5b.
What is the protein family that this protein belongs to?
Belongs to the conotoxin T superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GRPE_METMA
Sequence: MKKSRKKENMDSKERNQKEAERSEARNSESPAEKAGETKVSPENEPSSPEAEKNPEEACREENEILKDQLFRLAADFDNFRKRTARQMEENRKSVLEQVLLDFVEVTDNFDRAIKSARTAEDMGPIVSGIEQLSKQFFSILEKYGLERVKCEKAGEFDPHRHEAIHHIETSEVPDNTIVEIYKEGYALNEKVVRPALVSVARSPEEAEK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX20B_CTEON
Sequence: ACVPVYKECWYPQKPCCEDRVCQCSFGMTNCKCKARL
What is the function of this protein?
Antagonist of L-type calcium channels (Cav1/CACNA1).
What are the official names of this protein?
U10-ctenitoxin-Co1a, U10-CNTX-Co1a, Neurotoxin Oc FU-5.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 02 (plectoxin) family.
What are the subcellular locations of this protein?
Secreted.