PharMolix/UniProtQA huggingface dataset:
Protein: CHDC_BACCR
Sequence: MSEATTTLDGWYCLHDLRSIDWAAWKTLSSDERGQAVSEFLNVVEKWNEVATAKKGSHAMYTVVGQKADIMLMILRPTMEELNEIETELNKTTLAEYMVPAYSYVSVVELSNYLPADEDPYQNPQILARLYPELPKANHICFYPMDKRRQGDDNWYMLPMEERKKMMYSHSKIGRQYAGKVRQVISGSVGFDDFEWGVTLFADDVLQFKKLIYEMRFDEVSARYGEFGTFFVGNILPDEKVEKFLHI
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway.  The reaction occurs in a stepwise manner with a three-propionate intermediate.
What are the official names of this protein?
Coproheme decarboxylase, Coproheme III oxidative decarboxylase, Hydrogen peroxide-dependent heme synthase.
What is the protein family that this protein belongs to?
Belongs to the ChdC family. Type 1 subfamily.
Protein: MED19_XENLA
Sequence: MDGFSALFVPSEPSVPGSQSVVPTCTGAFVSGKTQAQTPIPGPPPTLPSSSSVEDNSRRPAAGPFYLLRELPGLSDLTASINLILHYNLEHSFSKFCGKKVKEKLSNFLPDLPGMIDTPGTPDNSSLRSLIEKPPICGNAFTPLTGALLTGFRLHTGPLPEQCRLMHIQPPKKKNKKHKQSRTQEPAPPETPSDSDHRKKKKKQREDDPERRKKKKDKKKKKSRHSPEHPGAGSSQSGLR
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 19, Mediator complex subunit 19.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 19 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL9_XANAC
Sequence: MDLILLQKVTNLGNLGDKVSVKPGYGRNFLVPQGKAVPATAANVEAFETKRAEYEAKANSILAEAQSRATKFEGASVTIGAHASTEGKLYGSVGPRDIAEAFTAAGLPLEKSEVILGEGAFRNVGEYDVVLHLHADVETTVKVIVESDA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: DXR_ACET2
Sequence: MVNRISILGSTGSIGVQTLDVARNLNIKVDGLAANKNIDLLEKQAREFQPKIVAVKDEERARILRDRLSDTDCKVVGGVEGLKMVASIETVETVVTSIVGIAGLIPTMEAIKHKKNIALANKETLVTAGHIVMSEAARMGVKILPVDSEHSAVFQSLMGNNKKDVAKIILTASGGPFRGRKKEELRNVTLREALNHPNWSMGSKITIDSATMMNKGLEVIEAHWLFEIPQDDIEVLVHPQSIIHSMVEYKDGSIIAQLGSPDMRLPIQFALTYPDRKQNNFSKLDIVKIGSLTFEAPDLEAFPCLGLAFEALRAGGTMPAVLNAANEKAVGLFLQEKIRFLDIPEIIEKVMGRHSVKPDPDIDDIIDVDLWARKIVEEIVK
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: MURE_HAEIE
Sequence: MKKLTALFNLPELKNDIELHNMVLDSRKVKAGDLFVAIKGHQVDGNQFIDSALHSGASAVVSETELSSEHLTVAFIGNVPVVKYHQLARHLSSLADVFYDSPSKNLTLVGVTGTNGKTTISQLLAQWAELLGLRAAVMGTIGNGLFGQIVEAKNTTGSAVEIQSSLSTFKHAGADFTSIEVSSHGLAQHRVEALHFKAAIFTNLTRDHLDYHQSMENYAAAKKRLFTELDTQIKVINADDEIGYQWLTKLPDAIAVSMNADFKVGSHQWMKAINIHYHFKGADITFESSWGNGVLHSPLIGAFNVSNLLLVMTTLLSFGYPLENLLATAKSLKGVCGRMEMIQYPNKPTVIVDYAHTPDALEKALIAAREHCQGELWCIFGCGGDRDRGKRPLMAQVAEQFAEKIIVTKDNPRTEPQSQIEADIVAGFKNMEKVGIIPDRAQAIQFAIESAVENDVILIAGKGHEHYQIIGSEVVHFSDQEIALDFLK
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLO2_BARHE
Sequence: MLIEQFICREDNFGVLIHDETSGYTAAIDAPESNAIQNALKRRNWTLQTIFLTHHHHDHVEALAELKQIYKAIVIGPEAEKEKISHIDQTLKPDESFLFGTHTILALSTPGHTLGALSYYFPQENLLFAGDTLFSLGCGRLFEGTPAQMLNSLKKLRQLPDETLLYCGHEYTKSNALFALTLDPYNQKLQQRAEDVFLLRAKNAMTLPVTLGQEKKNNPFLRWDNRTLRKTLRMEKETDEEVFAEIRKRKDNF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: FTSH_OPITP
Sequence: MLPIRWFLALLAVFLAVAGLDLWFSQTGARPSSATGEERLDGAAFLAAANAGELREGHIVYRANSTGLADLHAQRKGAAGAGATHVRATARLTDAEVTALRTQHFAEDDPVSYAAARAVSARERTASIVHAIVHPLGLITLIVGILFVVQRYAGRFTAFSAQRLRPVTSGVSFSSVAGCDEAKDEVYEVVEFLRDPARFRQTGGRMPKGVLLVGPPGTGKTMLAKAVAGEARANFYSLSGSDFVELYVGVGASRVRSLFKKARETAPSIIFIDEIDAIGRQRSAAESGGAQQEHDQTLNALLVAMDGFDSDDAVVVFGATNRPDTMDRALLRPGRFDRQVSVGLPDLRGRLAILQVHAGSVKLDPSVDLQEIAKATPGFSGADLANLLNEGAIHAARHRRATILHSDLDEARDKINWGRETRRVMTVQDKAVIAYHEAGHALMQVLSGEDVVRVQKVTIIPRGRSLGSTHFTPERDLFNYSQPQLIAKLRCLMAGRVAEEIALGSITSGASGDIQEATKTARQMVLEWGMSPLGFMALSRPDGDEPLASPQTFHEAERHVRALLDENYAATTRALTTHRAALDAIADELIRCETILGNDVRRIAAQHPPSALAG
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: DPS_SALAR
Sequence: MSTAKLVKTKASNLLYTRNDVSESDKKATVELLNRQVIQFIDLSLITKQAHWNMRGANFIAVHEMLDGFRAALTDHLDTMAERAVQLGGVALGTTQVINSKTPLKSYPLDIHNVQDHLKELADRYAVVANDVRKAIGEAKDEDTADIFTAASRDLDKFLWFIESNIE
What is the function of this protein?
During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages.  It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction.  One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.
What are the official names of this protein?
DNA protection during starvation protein.
What is the protein family that this protein belongs to?
Belongs to the Dps family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CARB_SULTO
Sequence: MRESVRKVLVIGSGPIKIAEAAEFDYSGSQALKALKEEGIETILVNSNVATVQTSRKFADKLYMIPVTWWAVEKVIERERPDGIMVGFGGQTALNVGVDLYNKGILQKYGVKVLGTPIEGIERALSREKFRETMINVGLPVPPSLSARSEEEALEKARQIGYPVMVRVSFNLGGRGSIVAWNEEELKRDIGRALSQSYIHEVLIEKYLHHWIELEYEVMRDKYGNSAVIACIENLDPMGVHTGESTVISPCQTLDNKEFQDMRFMSMDVAKSIDLVGECNVQFALDPKGYNYYVIETNPRMSRSSALASKATGYPLAYVSAKLALGYSLYEVLNKVSGSTCACFEPSLDYVVIKIPRWDLDKFENVEISLASEMKSVGEVMSIGRSFEESLQKAVRMLDIGEPGVVGGKIYFSKMTKEDALKNLKMRRPYWFLYAAKAFKEGATIDEVYEVTGINKFFLNKIKALVEFYEILRKQRNIDKDTLLQAKKLGFSDLQLAKALGVKESDIRKLREKWNIEPKVKQIDTLAGEWPAVTNYLYLTYNGTEDDIEFSEAGNKLLIIGAGGFRIGVSVEFDWSVVSLLDSSLKYFNDIAILNYNPETVSTDWDIARKLYFDEISVERVLDLIRKEKFTYVATFTGGQIGNNISKKLEEEGIRLLGTSGRSIDTAEDREKFSKLLDKLGIKQPEWISARSLEEVKEFISKVGYPVLIRPSYVLSGAAMKIVNNDLELMEYLKRATEVSPEHPVVISKYLNDAIEAEIDAAGDGKGVYGVVIEHVEEAGVHSGDATMSIPYRKLSSNVVNKMKENVHMIVRELEIKGPFNVQFVIKNNEPYIIELNLRASRSMPFSSKVVSKNIISLALDGILNGFGVDEFIELKPKSWGVKSPQFSWAQLKGAYPFLGPEMKSTGEAASLGTDFYDALLKSWLSSSPNKIPNKEGIALVYGTTNVEYLKIAAKNLIDYGITVYTLSEASIGIEEKSINDIIELIKNRKVEIVVTDGYLKHIDYEVRRIAVDYNIPIILNGRLGAEVTRAFSHPNVTYYEISEYGAGI
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: TTUC_PSEPU
Sequence: MPAHSFRIAAIPGDGIGLEVLPEGIRVLEAAALKHGLALEFDTFEWASCDYYLQHGKMMPDDWAEQLKQYDAIYFGAVDWPDKVPDHISLWGSLLKFRREFDQYVNIRPVRLFPGVPCALANRKVGDIDFVVVRENTEGEYSSLGGIMFENTENEIVIQESIFTRRGVDRILKYAFDLAEKRERKHVTSATKSNGMAISMPYWDKRTEAMAAHYPHVSWDKQHIDILCARFVLQPERFDVVVVASNLFGDILSDLGPACAGTIGIAPSANLNPERNFPSLFEPVHGSAPDIFGKNIANPIAMIWSGALMLEFLGQGDERYQRAHDDMLNAIERVIADGSVTPDMGGTLSTQQVGAAISDTLARLD
What is the function of this protein?
Has multiple catalytic activities.  Apart from catalyzing the oxidation of (+)-tartrate to oxaloglycolate, also converts meso-tartrate to D-glycerate and catalyzes the oxidative decarboxylation of D-malate to pyruvate.
What are the official names of this protein?
Tartrate dehydrogenase/decarboxylase, TDH, D-malate dehydrogenase [decarboxylating].
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNFD_SHESM
Sequence: MAFKIASSPHVTRNLHTSTVMQRVILCLLPGLVVQCAFFGWGTLIQVLLAIIVALSCEAAVMKLRNRSIKASLSDNSAMLTAILIGVAIPPLAPWWMIVMGTVFAIVIVKHLYGGLGHNLFNPAMAAYVLLLVSFPVQMTSWIAPSTVALNTPSVIDSLQLIFNVGAHGGMEQFRLGIDGISMATPLDTLKTDLSLGLTTTESMAKSIFDGGTGVGWFWVNLAYLAGGLVLLKLKAIRWHISTGVLAGLFVASSIGFLLSPDTQASPLFHLFSGATMLAAFFIATDPVTAATSPRGRLIFGALIGVLVYVIRTQGGYPDAFAFAVLLANLCAPFIDYYVRPRTYGHSAP
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit D, Rnf electron transport complex subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SSRP_BACLD
Sequence: MPKGEGKVVSQNKKANHDYFIEETYETGIVLQGTEIKSIRAGRVNLKDAFAKIERGEVFLHNMHISPYEQGNRYNHDPLRTRKLLMHRKQINKLIGLTKEQGYSLVPLKIYLKNGFAKVLLGLGKGKKKFDKREDLKRKDAKREIERAFRDRQKGLI
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: S31F3_RAT
Sequence: MLIPPFILWDVGYSVYTYGSIFIIALIIWQVKRSHRGLRMGPTKSCAKCFRRIKQTPSDRATRAKRTSKEEAEKLQKLLDTMKSQGWLPQEGSVRRLLCPDPSCSICNAMTLEIQQLLGVENKKTSSSLLRPSRSFSCLEALSPSKSLADRSSELTYQDTRDVSLSSRFPQSQETDQQSTRSATPSIGDAVLQCYHSAPQQQLDPQGSKMTQDAKGLSSSSTDEPGVPANQQKKRKKTKKLALKNQAAPTEVETENKMTFFSHWVNPEVKCDRQEESLVFSKYDTGAKPMTVEPEKTHSPVRDQAEGAEKKKKPECDLKAKPLRAKRNI
What are the official names of this protein?
Protein SPATA31F3, Protein FAM205C.
What is the protein family that this protein belongs to?
Belongs to the SPATA31 family.
Protein: PUR5_BACCZ
Sequence: MANAYKQAGVDIEAGYEAVSRMKKHVQTTMRKEVLGGLGGFGGMFDLSKFALEEPVLVSGTDGVGTKLMLAFMADKHDTIGIDAVAMCVNDIVVQGAEPLFFLDYIACGKAEPSKIENIVKGISEGCRQAGCALIGGETAEMPGMYSTEEYDLAGFTVGIVDKKKIVTGEKIEAGHVLIGLASSGIHSNGYSLVRKVLLEDGELSLDRIYGRLELPLGEELLKPTKIYVKPILELLKNHEVYGMAHITGGGFIENIPRMLPEGIGAEIELGSWEIQPIFSLLQEVGKLEEKEMFNIFNMGIGMVVAVKEEDAKDIVRLLGEQGETARIIGRTVQGAGVTFNGGKAL
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM3_CHLTR
Sequence: MLSAYYNDPFLADFCLGNIPLRLASRQSSLAVLQAHECLRKLQIFFPRLWGQIITTTTQGDLDQETPLCAVENTGFFTDDVDFLVQSGQCDLGIHSAKDLPENPKATVVSITASIDPRDILVFHEKYLSIPLPRRLRIGSSSVRRKELLSLLYPSAIITDIRGTIQTRLKLLEEKNFDAIVMANAAVSRLGLRLPCTKILPPPYHPLQGRLAITASRHIRSWRGLFLTCGITEDVEIMCFS
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Probable porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: ARMC9_XENTR
Sequence: MGDILAYEADLLGLVKEFLNFGEFQETLETFTKECKTKGKQLPKTSGLALRESKTLLIQKDLITAFEDGDIKEFFALWQEHIPVETQNTNPVAQKLEFYLQIHFAIFPLKHNQGRIDRTDCEERISHFKTYLETSGAALSQTTEFLPFYALPFVPHPAAHPSFKEIFQESWEAELRMRLEKFLSVILKATSTPRLITLYKESLHNNQELLQQLQQQLMETEHKARTYKKCFNRMQSDYHNLIGVTADLVDSLEATINGKLITPEYLQSVCTRLFSTQMKQSSAQSIDFTRPGTASSMLRASIAPLKQQEVPLFPSLDYEKLKKDLVFGNDRLKALILQALRWRLTRSQPGEQRNTVLQAYISNDLLDCHHNEQKNVLMLLRSPSEVVRQYTALLIDVFSSLAYGRVYISQNPRLLHSLVETWKAEEKESVIRETVLGILQKLSLRRSMQSAMIKDDLIFWLVQELEDTDHLSDYALQYTIALFMNLCLRSAGRKMCSRDADHVLKVLSDLLGHENHEIRSYVNGALYSILAVPSIREEARSMGMEEILRWYIREGNTDMNCHIEFIIKQLNSEDKFDESIESDDEEEEKDDEEDEDALEADLDKDEIIYAQSGELAGEKLLTTDYLGIMTNSFKVKKRMFGGVLQSADEPLQRPVTPSTHRVMNTVRKTSGPPSPPTNTFKTSQANMSVVSSRPPTRSGSRASTSDYCVTSDSIDSEASRLFSPSSQADQRGASSPRILDLGMEKHNGQNSSKAWLPRSPEVLSATSRKARTPTIAPQFSQSGPQQTSYSSSAGSSTRSRQSTQSYRK
What is the function of this protein?
Involved in ciliogenesis.  It is required for appropriate acetylation and polyglutamylation of ciliary microtubules, and regulation of cilium length (By similarity).  Acts as a positive regulator of hedgehog (Hh)signaling (By similarity).
What are the official names of this protein?
LisH domain-containing protein ARMC9.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium basal body. Cell projection, cilium. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localized to the proximal region in cilia. Stimulation of Hh signaling leads to redistribution of ARMC9 toward the ciliary tip within 6 hours, follow by a gradual return to its original proximal location (By similarity). Localizes to the daughter centriole of the primary cilium in RPE1 cells (By similarity).
Protein: YD15B_YEAST
Sequence: MESQQLSQHSPISHGSACASVTSKEVHTNQDPLDVSASKTEECEKASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWSFYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADSDMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELTFLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQYNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNMTVAELFLDIHAIYEEQQGSRNSKPNYRRNLSDEKNDSRSYTNTTKPKVIARNPQKTNNSKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLGQELTESTVNHTNHSDDELPGHLLLDSGASRTLIRSAHHIHSASSNPDINVVDAQKRNIPINAIGDLQFHFQDNTKTSIKVLHTPNIAYDLLSLNELAAVDITACFTKNVLERSDGTVLAPIVQYGDFYWVSKRYLLPSNISVPTINNVHTSESTRKYPYPFIHRMLAHANAQTIRYSLKNNTITYFNESDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPNSAPSYFISFTDETTKFRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSEYTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNYLWFSAIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGIPGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLTASYHSFIASNEIQESNDLNIESDHDFQSDIELHPEQPRNVLSKAVSPTDSTPPSTHTEDSKRVSKTNIRAPREVDPNISESNILPSKKRSSTPQISNIESTGSGGMHKLNVPLLAPMSQSNTHESSHASKSKDFRHSDSYSENETNHTNVPISSTGGTNNKTVPQISDQETEKRIIHRSPSIDASPPENNSSHNIVPIKTPTTVSEQNTEESIIADLPLPDLPPESPTEFPDPFKELPPINSRQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSLEPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIEAYHKEVNQLLKMKTWDTDEYYDRKEIDPKRVINSMFIFNKKRDGTHKARFVARGDIQHPDTYDSGMQSNTVHHYALMTSLSLALDNNYYITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLKKSLYGLKQSGANWYETIKSYLIQQCGMEEVRGWSCVFKNSQVTICLFVDDMVLFSKNLNSNKRIIEKLKMQYDTKIINLGESDEEIQYDILGLEIKYQRGKYMKLGMENSLTEKIPKLNVPLNPKGRKLSAPGQPGLYIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYKFRFDLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHKNKPTKPDNKLVAISDASYGNQPYYKSQIGNIFLLNGKVIGGKSTKASLTCTSTTEAEIHAVSEAIPLLNNLSHLVQELNKKPIIKGLLTDSRSTISIIKSTNEEKFRNRFFGTKAMRLRDEVSGNNLYVYYIETKKNIADVMTKPLPIKTFKLLTNKWIH
What is the function of this protein?
Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane.  Once in the nucleus, integrase performs the integration of the dsDNA into the host genome (By similarity).
What are the official names of this protein?
Transposon Ty1-DR6 Gag-Pol polyprotein, Gag-Pol-p199, TY1A-TY1B, Transposon Ty1 TYA-TYB polyprotein, p190.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RWD2B_PONAB
Sequence: MKIELSVQPWDPGYSSEGATAQETYTCPKMIEIEQAEAQLSELDLLASMFPGENELIVNDQLAVAELKDCIEKKTMEGRSSKVYFTINMNLDVSEEKMAMFSLACILPFKYPAVLPEITVRSALLSRSQQTQLNTDLTAFLQKHCHGDVCILNATEWVREHASGYVSRDTSSSPTTGNTVQSVDLIFTRLWIYSHHIYNKCKRKNILEWAKELSLSGFSMPGKPGVVCVEGPQSACEEFWSRLRKLNWKRILIRHQEDIPFDGTNDEMERQRKFSIFEEKVFIVNGARGNHMDFGQLYQFLNTKGCGDVFQMFFGVEGQ
What are the official names of this protein?
RWD domain-containing protein 2B.
Protein: DNAK_STRPY
Sequence: MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKNGEIIVGDAAKRQAVTNPETVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAEDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGMDKTDKDEKILVFDLGGGTFDVSILELGDGVFDVLATAGDNKLGGDDFDQKIIDFLVAEFKKENGIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFITAGSAGPLHLEMSLSRAKFDDLTRDLVERTKTPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKSVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSKSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDKNGIVSVKAKDLGTQKEQHIVIKSNDGLSEEEIDRMMKDAEANAEADAKRKEEVDLKNEVDQAIFATEKTIKETEGKGFDTERDAAQSALDELKAAQESGNLDDMKAKLEALNEKAQALAVKMYEQAAAAQQAAQGAEGAQANDSANNDDVVDGEFTEK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: GLUQ_PSEP1
Sequence: MPSLTMTDSSYIGRFAPTPSGFLHFGSLVAALASWLDARAVNGRWLLRMEDTDPPREMPGARDAILQTLERYGLHWDGEVVFQSQRHDAYAAVVDRLFNMGLAYACTCSRKQLERYNGIYPGFCRNAGHAREGAAIRLRVPELIYRFTDRVQGEYQQHLGREVGDFVIQRRDGLYAYQLAVVLDDAWQGVTDIVRGADLLDNTPRQLYLQELLGFSQPRYLHIPLIVQPDGHKLGKSYRSPPLQAEHATPLLLRALRALGQETDPELLLATPAEVLAVARTQWRPEAIAQRTTVPEADLR
What is the function of this protein?
Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp).  Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.
What are the official names of this protein?
Glutamyl-Q tRNA(Asp) synthetase, Glu-Q-RSs.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
Protein: ASSY_MARMS
Sequence: MSDVKKVVLAYSGGLDTSVIAKWLQEEYNCEVVTFTADLGQGEEVEPARAKAQALGIKEIYIEDLREEFVRDFVFPMFRANTIYEGEYLLGTSIARPLIAKRLIEIANETGADAISHGATGKGNDQVRFELGAYALKPGVKVIAPWREWDLTSRETLMAYCEEHKIPVDFSTKKKKSPYSMDANLLHISFEGDQLEDPWTEPEDDMWRWSVSPENAPNEPTYIEIGYEKGDPVSINGEAMSPATILETLNKVGGANGIGRVDIVENRFVGMKARGCYETPGGTIMMKAHRAIESITLDREAAHLKDEMMPRYAKLIYNGFWWSEERRMMQALIDTSQKYVNGTVRLKLYKGNVTVVGRQSDNSLFDSKIATFEDDAGAYDQKDAAGFIKLNALRMRIAAQKGRGFLDNDK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSSY_CAUVC
Sequence: MKEQGLPAVNIIACASPLLCTTTSSDCVSVWACELEQPLSDALGKLKDHPVDLGPSTQLLTLRPGGPLPRVAVDLRKRVLDVVAAALLTALFAPLLLLAALAIKLESPGPALFRQTRGGLGGAPFQILKLRTMHCREDGPDVAQAQRGDDRVTRVGRILRAASIDELPQLLNVLRGDMSLVGPRPHATAHDDYYSARIPEYAARYQARPGLTGLAQVRGLRGGTETVELMRQRIAADIDYIQTWSLWRDLKIVLRTVPSLLTTDNAY
What is the function of this protein?
Is likely the initiating enzyme for holdfast polysaccharide synthesis.  Catalyzes the transfer of the glucose-1-phosphate moiety from UDP-Glc onto the carrier lipid undecaprenyl phosphate (C55-P), forming a phosphoanhydride bond yielding to glucosyl-pyrophosphoryl-undecaprenol (Glc-PP-C55).  Also possesses a weak galactose-1-P transferase activity.
What are the official names of this protein?
UDP-glucose:undecaprenyl-phosphate glucose-1-phosphate transferase, UDP-Glc:Und-P Glc-1-P transferase, Glucosyl-P-P-undecaprenol synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial sugar transferase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PHNC2_RHOP2
Sequence: MLVVEGLTCRFGNHAAVDNASFAIERGSFIGVIGRSGAGKSTLLRMLNRLAEPSEGRILFEGIDVTALQGRELRQWRARSAMIFQQFNLVGRLDVLTNVLMGRLAHMPAWRSLAQAWPEKDRALAMSALDQFDMAPFAAQRADQLSGGQQQRVAIARALVQQPDIVLSDEPIASLDPRNTKIVMDALLRINKHFGITVICNLHSLDLARVYCDRLIGMAAGRVVFDGAPAELTDRVARELYDLEANDVMGADHHAPVVPTLPALPAYAQAVATG
What is the function of this protein?
Part of the ABC transporter complex PhnCDE involved in phosphonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphonates import ATP-binding protein PhnC 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RPO6_METJA
Sequence: MKLTKFEIARILGARSLQISSGAYATIETKCDSSLKIAYEEIKQGKVPLKPIRPVKA
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo6, DNA-directed RNA polymerase subunit K.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_RHOPB
Sequence: MARAAELSDVMSVQALHDEARAKVNLTLRVLGRRVDGYHELESVVAFADCADRLTLQAGSELSLTATGPRVQECGDNADNLVIKAARLLGERVADLRTGSFALDKQLPIAAGIGGGSADAAAALRLLARANDLALDDPRLIDAARKTGADVPVCLASKSCIMTGIGETLLPLALPRLPVVMVNPRVAVATKDVFAALGLRSGQLRVGVTDVVTAPKWPDQAAPLDAWIAVLAAGINDLEAPAKKLQPVIGEVLKLLGKARGARLARMSGSGATCFAIFADAAAAEAAAQSVSAAHPDWWVHAGTLG
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.