PharMolix/UniProtQA huggingface dataset:
Protein: CAER4_XENLA
Sequence: MFKGILLCVLFAVLSANPLSQPEGFADEERDVRGLASLLGKALKATLKIGTHFLGGAPQQREANDERRFADGQQDYTGWMDFGRRDGQQDYTGWMDFGRRDDEDDVHERDVRGFGSFLGKALKAALKIGANALGGAPQQREANDERRFADGQQDYTGWMDFGRRDDEDDVNERDVRGFGSFLGKALKAALKIGANALGGSPQQREANDERRFADGQQDYTGWMDFGRRNGEDD
What is the function of this protein?
The pharmacological activities of caerulein are quite similar to the physiological activities of gastrin and related peptides.
What are the official names of this protein?
Preprocaerulein type-4, Preprocaerulein type IV.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MURG_PROM2
Sequence: MSKKNNLLVAASGTGGHIFPALAVSKEVEDKWNIHWLGVKQRLDSNLIPKKYNLRTLSIKTPRKNIFLFYQYIEILMSTFQIIRILKEKKINLVFTTGGYISAPTIIASKFLRIPVIIHESNLIPGMVTKYFGFLCNYVLLGFKNTNSYLRNCKTIFTGTPLREQFYKSNPLPEWVPKGKGPLLIVMGGSQGAKAINQILNESLEFLLKKQFRIVHIIGESNQQPFYIKNTKNYIQKKFTNEVAALIQNCDLVISRSGAGTINELIEAEKPSILIPYPDSKNNHQEKNAMIIAESGGSVLINQNNISKEVFEETLERIFKIKSKKGVNHYEILDLMKRNMVNNKIKSKNEIKKFINYFLKEF
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RECO_TRIEI
Sequence: MAKLYKATGINLKAMALGESDRLLTILTPEYGLIRVVAPGVRKQKSKLGGRGELFVVNQLLISKGRSLDRINQAETITSYTGLSQNLGKLAAGQYLAELVQQIALKENPQTELFHLLNEHLERIEQLQHKTDRLWSTQLIAFLAHGIYHLLAIEGIAPQVHQCCATGNELQPDFNNSKWQVGFSIDAGGIIKVDETSVVQSFCKDLSDYYLSTKINTLINANQLSLLQQLPQPQLQTIVKLTSYQDWVKVEQLLRKYTQYHLGYSIRSAELIDTYLKSISPLINNATI
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: PK1_NPVAC
Sequence: MATTNATLQTLVQFYENCKNVKTRYKIINGRFGKISILSHKPTSKLYLQKTISAHNFNADEIKVHQLMSDHPNFIKIYFNHGSINNQVIVMDYIDCPDLFETLQIKGELSYQLVSNIIRQLCEALNDLHKHNFIHNDIKLENVLYFEALDRVYVCDYGLCKHENSLSVHDGTLEYFSPEKIRHTTMHVSFDWYAVGVLTYKLLTGGRHPFEKSEDEMLDLNSMKRRQQYNDIGVLKHVRNVNARDFVYCLTRYNIDCRLTNYKQIIKHEFLS
What is the function of this protein?
Serine/threonine protein kinase that plays a role in viral propagation by phosphorylating various viral and cellular substrates including the viral p6. 9 protein or host histone H1.  Participates in nucleocapsid assembly and polyhedra formation.
What are the official names of this protein?
Serine/threonine-protein kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: RS3_SYNSC
Sequence: MGHKINPTGLRLGITQEHRSRWYASSKNYPALLQEDDRIRKFIHKKYGSAGISDVLIARKADQLEVELKTARPGVLVGRQGSGIEELRSGIQKTIGDSSRQVRINVVEVERVDGDAFLLAEYIAQQLEKRVAFRRTIRMAVQRAQRAGVLGLKIQVSGRLNGAEIARTEWTREGRVPLHTLRADIDYATKVASTTYGVLGIKVWVFKGEVLSEQAQPMPVGAAPRRRASRRPQQFEDRSNEG
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: ZCH24_MACFA
Sequence: MSLLSAIDTSAASVYQPAQLLNWVYLSLQDTHQASAFDAFRPEPTAGAAPPELAFGKGRPEQLGSPLHSSYLNSFFQLQRGEALSNSVYKGASPYGSLNNIADGLSSLTEHFSDLTLTSEARKPSKRPPPNYLCHLCFNKGHYIKDCPQARPKGEGLTPYQGKKRCFGEYKCPKCKRKWMSGNSWANMGQECIKCHINVYPHKQRPLEKPDGLDVSDQSKEHPQHLCEECKVLGYYCRRVQ
What are the official names of this protein?
Zinc finger CCHC domain-containing protein 24.
Protein: ATG4_CANGA
Sequence: METIHNISNRLQEVLATNKSVNVDTDNDSLSSNQEDNEVEKVRHLVVILGEKYSYAVDRNTGINALMQWFTTNSEIPEEILNAIRSKLNFTYRTNFEPIERAPDGPSPINPLIMLRINPIDAIENVFNNRECFFTDVGWGCMIRTGQSLLGNALQRVKSTVKDQPYIYEMDDTKEITDLFKDNTKSAFSLQNFVKCGRIYNKIAPGEWFGPATTATCIRYLIQENPCYGIEACYISVSSGDIFKENIQGMIDRYPNGNILILLGIKLGLDSVHERYWGEIKTMLESPFSVGIAGGRPSSSLYFFGYFDDTLLFFDPHNSQTALIDDFDESCHTENFGKLNFSDLDPSMLLGFLLPCSKWDEFQEFTSLLTIVNVLDGMDQYRDPDLNSNDIGNVELSPQLKLSQTPDAITDDDYVDIGALIQGNSMNINDRDNGYQEVQCKNQQIVIMDSLNETKPLEIEKVLVGQGTNLVNATTPCREAFPK
What is the function of this protein?
Cysteine protease that plays a key role in cytoplasm to vacuole transport (Cvt) and autophagy by mediating both proteolytic activation and delipidation of ATG8.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  The protease activity is required for proteolytic activation of ATG8: cleaves the C-terminal amino acid of ATG8 to reveal a C-terminal glycine.  ATG8 ubiquitin-like activity requires the exposure of the glycine at the C-terminus for its conjugation to phosphatidylethanolamine (PE) and its insertion to membranes, which is necessary for autophagy.  The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy.  In addition to the protease activity, also catalyzes deconjugation of PE-conjugated forms of ATG8 during macroautophagy: ATG8 delipidation is required to release the protein from membranes, which facilitates multiple events during macroautophagy, and especially for efficient autophagosome biogenesis, the assembly of ATG9-containing tubulovesicular clusters into phagophores/autophagosomes, and for the disassembly of PAS-associated ATG components.  ATG8 delipidation by ATG4 also recycles ATG8-PE generated on inappropriate membranes to maintain a reservoir of unlipidated ATG8 that is required for autophagosome formation at the PAS.
What are the official names of this protein?
Probable cysteine protease ATG4, Autophagy-related protein 4.
What is the protein family that this protein belongs to?
Belongs to the peptidase C54 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Preautophagosomal structure.
Protein: RS16_CLOD6
Sequence: MAVKIRLKRMGANKKPFYRIVVADSRAPRDGKFIEEIGYYNPISEPKQVRINDEKAIKWLATGAQPTEVVKKLLVKNGVIEKFEASKQAK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: RSXE_ESCF3
Sequence: MSEIKDVIVQGLWKNNSALVQLLGMCPLLAVTSTATNALGLGLATTLVLTLTNLTISTLRRWTPTEIRIPIYVMIIASVVSAVQMLINAYAFGLYQSLGIFIPLIVTNCIVVGRAEAFAAKKGPALSALDGFAIGMGATGAMFVLGAMREIIGNGTLFDGADALLGNWAKVLRVEIFHTDSPFLLAMLPPGAFIGLGLMLAGKYLIDEKMKKRRAKTVVNEIPAGETGKV
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit E, Rsx electron transport complex subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AROK_METCA
Sequence: MRNRRNIFLIGPMGAGKTTVGRLLARALGMEFWDSDKEIERRTGVTVPMIFEYEGEAGFRRRESEVIADLTGKERIVLATGGGSVLAAENREHLAARGLVIYLQCSVQKQLERTHKDMNRPLLQTENPRQRLEELLRVRDPIYRELADYVVDTGQHSSRSAVRRIINAYEKSGTRLRTE
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HXA9_CAVPO
Sequence: NSGTVLLLVSEGGSSRSRSSWCCNLKQLAFAGLAGDPAWRSQLPLGSDSEMCQVDREKQPNEGAFSENNAENDSSGDKPPIDPNNPAANWLHARSTRKKRCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKKINKDRAKDE
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-A9, Homeobox protein Hox-1.7.
What is the protein family that this protein belongs to?
Belongs to the Abd-B homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PGK_SALTO
Sequence: MTIRTLDDLLAEEVTGRRVLVRADLNVPLDKQTGQIADDGRIRAVLPTLSALVQAGAKVVVCSHLGRPKGSPNPVFSLRPVAGRLGELLGAPVHFAEDTVGDSARSTVADLADGQVALLENLRFNPGETSKDEAERGAFADQLAALADAYVDDAFGAVHRRHASVYDVPARLPHVAGRLVLREVEVLGTLAGEPDRPYVVVLGGSKVSDKLAVIEALLPKVDRLLVGGGMCFTFLKAQGHEVGSSLLEEEMVETCRSLLERADGKIMLPVDVVAADAFAPDAPHDTVRADGIPSKRVGLDIGPETVAGFAAALRGARTIFWNGPMGVFEMAAFAHGTRGVAEAIATSDAFTVVGGGDSAAAVRALGLDEQAFSHISTGGGASLEYLEGKTLPGIAALES
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGB_CRYNB
Sequence: MTAVSLSDGTAVLKTDPWLEPFSGALRERYAAYQKQRTIIEEHEGGLAEFSKGYKSMGFQIDKNGGVRYREWASNATEARLIGEFNNWSHTANPMTKSPFGVWECYVPPVSPGVCAIPHDSMVKISMTLPGGESIDRIPTWITRVTQDLNISPIYDGRFWNPPKEQQYQFKHGHSTRPVEGLKIYEAHVGISSPNMRVTTYKEFEVDVLPKIKQLGYNCIQMMAIMEHAYYASFGYQVTNFFAASSRFGTPEELKSLVDKAHELGLTVLLDVVHSHASKNILDGINMYDGSDHLYFHEGGRGRHDQWDSRLFNYGQHEVLRFLLSNLRFWMDIYMFDGFRFDGVTSMMYKHHGIGSGFSGGYHEYFGDSVDLEAMVYLMLANAMLHETYPHVVTIAEDVSGMPTLCRPVAEGGVGFDYRLSMAIPDMWIKLLKEYTDDQWEMGQIVHNLTNRRHLEKSVAYAESHDQALVGDKTLAFWLMDKEMYDFMSDLSPLTPIIDRGLALHKMIRFIVHTLGGEAYLNFEGNEFGHPEWMDFPREGNGNSFAHARRQFNLVDDKLLRYKYLYEFDVAMNWLEDKYKWLNSPQAYVSLKHEGDKMIVFERAGLLFIFNFHPTQSFTDYRVGVDTAGEYKVILTSDETRFGGHNRIDMGGRYFTTPMEWNGRKNWLQVYSPSRTVLVLGL
What are the official names of this protein?
1,4-alpha-glucan-branching enzyme, Glycogen-branching enzyme.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: RS5_PSEPK
Sequence: MANNDQKRDEGYIEKLVQVNRVAKTVKGGRIFTFTALTVVGDGKGRVGFGRGKSREVPAAIQKAMEAARRNMIQVDLKGTTLQYATKAAHGASKVYMQPASEGTGIIAGGAMRAVLEVAGVQNVLAKCYGSTNPVNVVYATFKGLKAMQSPESIAAKRGKSVEEIF
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: GAL1_LEVBA
Sequence: MDFASLATEYQEKFDVAPQRVFFSPGRINLIGEYTDFNGGHVFPAAISMGTYAAYSARDDKQFRVYSANVPDAGVLTFSLDNLAFDKADNWANYLKGMLFELAKQDLTIDHGFDLFVHGNLPDASGLSSSASMEMLMGEILHAAYGMKLDEVEMVKVGQQVENDYFGLNTGIMDQFAIGMGKKDQAILLDTNTMDYEYAPLALGDYVVVIMNTKKRRELTDSKYNERRAQCEEALRRLQTKLDIKTLGDLNEDEFDENAYLINDDVLIKRARHAVFENQRTLKAFDALQKNDLQRFGHLVNASHISLNYDFAVTGKELDTLVETAWQQPGVLGARMTGAGFGGCAIAIVKKDNVADFEAQVGKTYEDTIGHPAEFYVAEIADGPAEL
What is the function of this protein?
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_FRACC
Sequence: MTSPLDGLIAEHAEIEGQLADPAVHNDPAKARALSRRYAQLAPVVDLARELDRVEGDLAAARELALLDPSFRDEVQDLGEELARLNDRLRAYLVPIDPDDARDAILEVKAGAGGEESALFAGDLLRMYLRYAERRGWKTEILDANPSDLGGYRDVSVAVKARGPAGPGDGVYGRLRFEGGVHRVQRVPVTESAGRIHTSAAGVLVLPEAEEVDVEIDPNDLRIDVFRSSGPGGQSVNTTDSAVRITHIPTGVVVSCQNEKSQLQNKESALRILRARLLGAAREKAESEASLARASQVRTVDRSERVRTYNFAENRISDHRVGYKAHNLDQVLDGELDEVLDALAAADLDARLAAQAS
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCGG_SCHPO
Sequence: MDIVAETQIEEESLIPDATSTPLETEVVADTTLRKTALHLAGVDNLSEEQVKGFISAYAPESQCTIEWINDNECNVVYADDDVSRNALFHLIMESPTEFSEELEYQTKPHPTVPTCQFKIRYARYGDKKVKSAHLYSRYYLFHGDPREEKAQKSKSKSRNQDERGSPLDERLGPKVSDLTLMERIFQVRRKPRKSRRDRRSRVSKR
What are the official names of this protein?
Uncharacterized protein C16C4.16c.
Protein: UPPP_SHESM
Sequence: MDTFQVIILALIQGLTEFLPISSSAHLILPAQLLGWEDQGLSFDVAVNTGSLFAVVIYFRNELWAMFKAWIASMVKGQHSDDSKLAWWIILATLPAVFFGFIAKDFIETHLRSAGVIAVTTIVFGLLLWWADKMSRRDLTVYQTGWRKALLIGFAQALALIPGTSRSGATMTAALMLGLSRDAAARFSFLMSVPVSLGAAILVGKDLAESPLPIDFQALTLGTVISFVAAYLCIHYFLKIISRMGMTPFVIYRLILGAVLCGFIFL
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HSP70_LEIBR
Sequence: KSQIFSTYADNQPGVHIQVFEGERAMTKDCHLLGTFDLSAIPPAPRGVPQIEVTFDLDANGILNVSAEEKGTGKRNHITITNDKGRLSKDEIERMVNDASKYEQADKMQRDALEAKNGLENYAYSMKNTVSDTNVSGKLEESDRSALNLAIDTALEWLNSNQEASKEEYEHRQKELESTCNPIMTKMYQSMGGGAGGMPGGMPDMSGMGGGQGPAAGASSGPKVEEVD
What are the official names of this protein?
Heat shock 70 kDa protein, HSP 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: METK_SHEPW
Sequence: MAKHLFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGMVMVGGEVTTSAWVDIEEITRKTVREIGYTHSDMGFDADSCAILNAIGKQSPDINQGVDRADPKEQGAGDQGLMFGYANNETDVLMPAPITYSHKLVKRQSEVRKDKTLPWLRPDAKSQVTFAYNNDGSIAGIDAVVLSTQHREDVSQADLIEGVMETIIKPVLPAKWLSKDTKYFINPTGRFVIGGPVGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVSYAIGVAEPTSISIETFGTAKVAEELLIDLVRRHFDLRPYGLTEMLNLARPIYQATAAYGHFGRNEFPWEATDKAEALRADAGL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPO1C_METM6
Sequence: MQMADLEKKLENSVLPPLLKRELSEKILKEEISEEYLVDEIISETIRAYERTLVEPGEAVGVVAAQSIGEPGTQMTMRTFHYAGVAELNVTLGLPRMIEIVDARKEPSTPTMTIYLNDDFKGDREKASMVAKNIESTNVESVSEDISVDLINECITIVLNTHQLESRGLTVADVIESIKSKMKLKIEDHENVLNLKIKTPSLKALRKRLPKVRAIHLKGVQNIKRVIIRKEVDEYILYSEGSNIKEVFDIEGVDTTKTTTNNIVEIQDVLGIEAARNAIIYEMDATLGNQGLTVDKRHLMMVADLMCTDGVVKPIGRHGIGGEKASVLARAAFEETVKHLYSASMRGYVDELGGVVENIIVGKPIAMGTGCIDVCIDKTYEEGKEL
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Forms part of the jaw domain.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo1C, DNA-directed RNA polymerase subunit A''.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IXTPA_STRP1
Sequence: MSEKIYEYKDENNWFIGKMTGHNLISGWGVKHTTIKKIDDLLDGIAATLDWENPKGYDVSVVRHQSPLSLITFIIDMINQETQREIKVTPHAGTILLMENAKLLAVYLPEGGVSTATFFATSEQGFGDIILIATRNEGKTKEFRNLFGQLGYRVENLNDYPELPEVAETGTTFEENARLKAETISRLTGKMVLADDSGLKVDALGGLPGVWSARFSGPDATDAKNNAKLLHELAMVFDQKKRSAQFHTTLVVAAPNKDSLVVEADWPGYIATQPKGENGFGYDPVFIVGETGHHAAELEADQKNQLSHRGQAVRKLMEVFPAWQAKQS
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: FAM3C_XENTR
Sequence: MRIAGAIKFVIAVALFLLTFYVISQVFEIKMYSNLGNIFARSAPDTVAHPTTKAPRYRCGISKVCPEKHFAFKIASGAANVVGPKICVDDNILMSGVKNNVGRGINTALVNGKTGALIETTYHDLWGGEVGPFIEFLKKIPDGTIVLMATYDDGATKLNDDARKRIAELGSSLISVLAFRDNWVFVGGKGIKTKSPFEQHIKNNKDTNKYEGWPEVVEMEGCIPQKINE
What is the function of this protein?
Involved in retinal laminar formation.
What are the official names of this protein?
Protein FAM3C.
What is the protein family that this protein belongs to?
Belongs to the FAM3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS8_SYNS9
Sequence: MANHDPISDMLTRIRNASEKRHETTKVPASRMTRSIAKVLQQEGFISEINEEGEGFRAELVLSLKYSGKHRLPTIRSMQRVSKPGLRIYKNTRGLPKVLGGLGVAIISTSKGVMSDRDARREGVGGEVLCYVY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: PUS7_DROME
Sequence: MGKDRGRGRRNNHSGPYNKSNWRGQKKDRPQNNGGGQRNSAPQQKSTLLETQVGITEFTNPEAPGFTGILKSRFSDFHVNEIDSNGKVLELNDLSVPKVAIVAVAENELDNWRKELEAVIGPEVWQDIANLAKAKNDPAIEQKVEIDVTTLDKEQRTQVHQMIKQLYKGKLLSTTIGQQQAKPKVQEEASLENKDAAEGETSTQKDSQVPAEEKKTIKVFKPKPGRGDKRWSFPADYVTFLVHKTNLVTSDVASTLAARLNLRPSQVNYSGIKDKRAKTTQKFSVKRRTPESILVAARSQRNVHIGNFGFESNTLKLGDLQGNRFRIALRHIAKEKREEIEQALQSLKERGFINYYGLQRFGNSASVPTYEVGVALLKHDYKLACELILKPRDSDVEFLRPIREEWWKNRDSAAAAAQIYGEKFIEKKLLDGLARFGESDYSSALRQIPRNMLMLYPHAYQSLIFNRIASRRIKEFGLKLIPGDLVYVEQDQSEASEEQAQQGEALEEQKEEEPNDEPLEVPEGDEAIEEESIFKRKVRPLTAEDIASGKYKLCDVVLPLPGHDITYPSNECGAWYEEMLAEVGLSSDQLKHKEKTYALAGAYRKMIISSSDLKWSFRMYNTPEDTLIASDWELLKNIPVAPEPAEAEANYMALLLEFSLPTAAYATMFLRELLKQDTSSASQTQLEKQAMAKEDNEKKAVGTQEEQMEVVKEVADEDGQETEQAETQGAEEAV
What is the function of this protein?
Pseudouridylate synthase that catalyzes pseudouridylation of RNAs, such as tRNAs and mRNAs.
What are the official names of this protein?
Pseudouridylate synthase 7 homolog.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: Y2076_DICDI
Sequence: MSNETFEQNEPKPTKVEELQPGDVEAVEDSTPVREITQTDHINKAMLQI
What are the official names of this protein?
Uncharacterized protein DDB_G0268274.
Protein: ATOS_DROME
Sequence: MIPTSVTNSPPPAGLGQNGASASLGSATAAAGGGMLSGLGMVAVSGCGSAGTGAQNNYGSVVLGLASLILEGRPIADDEYQQQTVGVVGSGAATAGSGGGRLSPRPSTSRAAINITTNPYGSMGGSENRAVNGSGSTGSPSSSSLTHQRWTQKLCQLRQISPAAQTMSAEPELVSLAINDLNKDHGDYEIVRRVMLNRAGGTGLVSSAGGGTNNSSAASSPGSNSSDNILHSLQSLATTCLRGGPALAPPPSVESRPLNLAFHWSGLGGSGGRGLGFGGGAASISNTPTTTATATASSGASSSASRPKHGPHCDQFLRKMGLAKGEMPSEAEEHICDMSYVNMTCNRWRAYCMKMEAILARREPVCIEVYLGPVSHKLLLEQWIICGREKVPPPTMTLPSLCSAIRSQLYFSQIVAWCDLLRKCDPSVYDSGRVIFSNCGNNAGDLATSYTTCGGQKRPRLNIFYRIKQHTTTNSNSGLHQEDGFSAKANVHNFPNVNVSESYSISVSVRSLPRINGGLPHVEPLPPSPAPRSLRPCGGDPASTPTGGGGLHAATPTGLGARTSALTPTTTAGGSNCDNGKPGMGQILDELDGDTSLSHRERQLQKYRKRMQRRDKKRERKATPDRLNSRQQSEEPMDEGEESQTQSQTTSETQSLALTLQQPRRIAMISTGTQTSLSSCQQCGSEKTLLCLSCTGGGGAHGGSNGTANGSTNGATDDGDDSDTTASEMEETSSCSLSSADLIVGTPRNNAELLLQAIQRTPKNRNRKPHPGVLDQVSCRNADLNGGQNNNLLKATPATSGCQVCKRQKTQHNFANGKVHQPTNGKQASNGYASMHLEAEKQPDVVQILATKLTPNIERCSLNPVERCKTPPPGVADHIVVQFKTPLSQVPAKHQPDAMVPLQQQQLGKSSSKPAQLRLNCGSNLLESETPPPMTSPQMRKALPKVNLTTIFCSSAPIAIGCPAFSFDPAALSHARSQLLAPDVSVTPPVQKSFSAPTLPHAASLSVSPRFSKQALAAHKRRSRHLSDRSDRSSLGSDEQLSDEDLESGLCSPAGGSPLKCRARLAAQFGGRPLLGNLEESLLQRRLMPKIEVMGFTLQLGASGGFCPTQVNIPAVSYFYELHGETLSTPYLCEIRLPRKGYSVPRSGTVQATLLNPIGTVVRMFVIPYDMRDMPPLHRTFIRQRILAEELSQDQDEGHKVPRSPTVTSTTSKLGHFISAEQMKRLRYSIHLKFQTSRSGRLCLHTDIRLLISRRTDCDTAAAHAKGVLEAPNELVTDTMMPAEPRYSARQESAGRI
What is the function of this protein?
Transcription regulator that syncronizes transcriptional and translational programs to promote macrophage invasion of tissues.  Required in macrophages for their early invasion into the extended germband.  Induces transcriptional expression of metabolic enzymes as well as of the translational regulator pths/DDX47.  With pths/DDX47, adjusts transcription and translation of a subset of OXPHOS genes to increase mitochondrial bioenergetics and allow macrophage tissue invasion.
What are the official names of this protein?
Protein Atossa.
What is the protein family that this protein belongs to?
Belongs to the ATOS family.
Protein: DPYL1_MOUSE
Sequence: MSHQGKKSIPHITSDRLLIRGGRIINDDQSFYADVYLEDGLIKQIGENLIVPGGVKTIEANGRMVIPGGIDVNTYLQKPSQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGSSLLTSFEKWHEAADTKSCCDYSLHVDITSWYDGVREELEVLVQDKGVNSFQVYMAYKDLYQMSDSQLYEAFTFLKGLGAVILVHAENGDLIAQEQKRILEMGITGPEGHALSRPEELEAEAVFRAIAIAGRINCPVYITKVMSKSAADIIALARKKGPLVFGEPIAASLGTDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYLTSLLACGDLQVTGSGHCPYSTAQKAVGKDNFTLIPEGVNGIEERMTVVWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKMKTITAKSHKSTVEYNIFEGMECHGSPLVVISQGKIVFEDGNISVSKGMGRFIPRKPFPEHLYQRVRIRSKVFGLHSVSRGMYDGPVYEVPATPKHAAPAPSAKSSPSKHQPPPIRNLHQSNFSLSGAQIDDNNPRRTGHRIVAPPGGRSNITSLG
What is the function of this protein?
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton (PubMed:25358863, PubMed:14685275).  Plays a role in axon guidance (PubMed:14685275).  During the axon guidance process, acts downstream of SEMA3A to promote FLNA dissociation from F-actin which results in the rearrangement of the actin cytoskeleton and the collapse of the growth cone (PubMed:25358863).  Involved in invasive growth and cell migration (By similarity).  May participate in cytokinesis (By similarity).
What are the official names of this protein?
Dihydropyrimidinase-related protein 1, DRP-1, Collapsin response mediator protein 1, CRMP-1, Inactive dihydropyrimidinase, Unc-33-like phosphoprotein 3, ULIP-3.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Cell projection, growth cone. Cytoplasm, cytoskeleton. Perikaryon. Note=Associated with centrosomes and the mitotic spindle during metaphase (By similarity). Colocalizes with FLNA and tubulin in the central region of DRG neuron growth cone (PubMed:25358863). Following SEMA3A stimulation of DRG neurons, colocalizes with F-actin (PubMed:25358863).