PharMolix/UniProtQA huggingface dataset:
Protein: TVB51_HUMAN
Sequence: MGSRLLCWVLLCLLGAGPVKAGVTQTPRYLIKTRGQQVTLSCSPISGHRSVSWYQQTPGQGLQFLFEYFSETQRNKGNFPGRFSGRQFSNSRSEMNVSTLELGDSALYLCASSL
What is the function of this protein?
V region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition (PubMed:24600447).  Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.  Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333).  Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.  In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.  The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462).  The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement.  This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells.  Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585).
What are the official names of this protein?
T cell receptor beta variable 5-1.
What are the subcellular locations of this protein?
Cell membrane.
Protein: Y4833_BACHK
Sequence: MTENNDIKMVIITGMSGAGKTVALQSFEDLGYFCVDNLPPMLLPKFIELMADSKGKMNKVALGVDLRGREFFEHLWGALDDLSERTWIIPHILFLDAKDSTLVTRYKETRRSHPLAPTGLPLKGIEIERSLLTDMKARANIVLDTSDLKPKELREKIVHLFSTETEQAFRVNVMSFGFKYGIPIDADLVFDVRFLPNPYYIPHMKPLTGLDEEVSSYVLKFNETHKFLEKLTDLITFMLPHYKREGKSQLVIAIGCTGGQHRSVTLTEYLGKHLKPEYSVHVSHRDVEKRKGH
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein BT9727_4833.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: DCK2_CHICK
Sequence: MSAPAKRRCRGPAADLDSSFQKRLRKISIEGNIAAGKSTLVRLLEKHSDEWEVIPEPIAKWCNIQTSEDECKELSTSQKSGGNLLQMLYDKPTRWAYTFQTYACLSRVRAQLKPISAKLHEAEHPVQFFERSVYSDRYVFASNLFESGNINETEWAIYQDWHSWLLNQFQSEIELDGIIYLRTTPQKCMERLQKRGRKEEEGIDLEYLENLHYKHETWLYEKTMRVDFENLKEIPILVLDVNEDFKNDKIKQEYLIDEIKSFLTS
What is the function of this protein?
Phosphorylates the deoxyribonucleosides deoxyadenosine, deoxycytidine and deoxyguanosine (PubMed:27906638).  Shows highest activity against deoxyguanosine followed by deoxycytidine and then deoxyadenosine (PubMed:27906638).  Shows only very minor activity against deoxyuridine and deoxythymidine (PubMed:27906638).
What are the official names of this protein?
Deoxycytidine kinase 2, GgdCK2, Deoxyadenosine kinase 2, Deoxyguanosine kinase 2.
What is the protein family that this protein belongs to?
Belongs to the DCK/DGK family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS7_FRASN
Sequence: MPRKGPAPKHPVVVDPVYGSPLVTALVNKVLLSGKKSVAERIVYGALEGAKNKTGNDPVVTLKRALDNVKPTLEVRSRRVGGATYQVPVEVRAGRSTTLALRWIVGYSRGRREKTMTERLMNELIDASNGLGASVKRREDTHKMAESNKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: MURD_NITWN
Sequence: MIPVTSFSGKTVAVFGLGGSGLASCHALKAGGAEVIAGDDNADNLAKAAQAGFITADLRTVVWANLAALVLAPGVPLTHPSPHWSVLAARQAGVEVIGDVELFCRERARHAPDAPFIAITGTNGKSTTTALVAHLMREAGYDVQMGGNIGTAILSLEPPRRGRVHVIEMSSYQIDLAPSLDPTVGILLNLSPDHLDRHGTIEHYAQVKERLIAGVQPQGTAVVGVDDHWCAAIADRQEQAGRSVVRVSVKRPLAHGVSVEQDRIVLVSGGARSEIADIGGIGSLRGRHNAQNAACASAGALALGVSRDILQQDLRSFPGLAHRMEQVGRKAHVLFVNDSKGTNADATEKALSSFDEIFWIAGGKPKSGGIASLDAFFPRIRKAYLIGEAAQEFAATLEGKVAYEISGTLEAAVPAAARDAEGAGRAGAVVLLSPACASFDQFRNFEVRGDRFRELVQALPGVTPVV
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BTG1_CHICK
Sequence: MHPALYTRASMIREIAAAVAFISKFLRTKGLMNERQLQTFSQSLQELLAEHYKHHWFPEKPCKGSGYRCIRINHKMDPLIGQAAQRIGLSSQELFQLLPSELTLWVDPYEVSYRIGEDGSICVLYEAAPAGGSQNNTNMQMVDSRISCKEELLLGRTSPSKSYNMMTVSG
What is the function of this protein?
Anti-proliferative protein.
What are the official names of this protein?
Protein BTG1, B-cell translocation gene 1 protein.
What is the protein family that this protein belongs to?
Belongs to the BTG family.
Protein: KACL_STRKN
Sequence: MSTHPVLDWSRSAEHLRRSHGVTTDPRPDEDGHYPCVLTRGSGTRVYDLDGNAYLDLTGSFGSVLIGHAEPAVVRAVTDVLSEGNLFYTGASPRRLALAERLLDWFPWSEQAIFYRTGSCAVSAAARLAQHATGRNRVLSSGYHGWHDWHLEAVPEAKPKTFESYATEFHNDLALYRSWLDRHGEEIAAVVVTPEPHRFDHAYYQELREVAKEHGCLFVVDEVKTGFRAGAGGFSALAGIEPDAVTVSKGMANGHSISAVVGQRQLTQELSEAHVWSTYQNEQVGFAAALASLDFLERHDVAAVTRRTGEAVRQGVLQLFAEHGLPVGAPGWGPMFELDFDAADEGLAERLEAALLRHGIFCDTGDDFNMMFHTAEHTDELLERFAAALGDL
What is the function of this protein?
Aminotransferase that has 6'-oxoglucosaminyl:L-glutamate aminotransferase activity by catalyzing pyridoxal-5'-phosphate-mediated transamination leading to the conversion of paromamine to neamine in the biosynthetic pathway of kanamycin B.
What are the official names of this protein?
2'-deamino-2'-hydroxyneamine transaminase, Kanamycin biosynthesis protein B, Neamine transaminase KanB.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
Protein: HEI10_ORYSJ
Sequence: MKCNACWRELEGQAVSTTCGHLLCTEDAKKILSNDAACPICDQVLSKSHMRPVDTNPNDDWTNMSMAGVSPQILMKSAYRSVMFYIGQKELEMQYKMNRIVGQCRQKCELMQAKFTEKLEEVHTAYQKMAKKCQLMEQEVENLSRDKQELQEKFAEKSRQKRKLDEMYDQLRSEYESAKRSAIQPANNYFPRAQPDLFSGVPNIMDSSDPLRQGLAGLPETPGRRDEGWAPPPRQRRSTSGPFELSAGSPAHNAAPPVDIRPRQPARPVFGTAMNNTSAALRNMIISPVKRPQLSRNRPHMFT
What is the function of this protein?
Ubiquitin E3 ligase required for class I crossover (CO) formation during meiosis.
What are the official names of this protein?
E3 ubiquitin-protein ligase CCNB1IP1 homolog, RING finger-containing protein HEI10, OsHEI10, RING-type E3 ubiquitin transferase HEI10.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Dynamic localization on the meiotic chromosomes. Initially appears as distinct foci. Later observed along the chromosomes and finally restrict to prominent foci that specially localize to chiasma sites. Extends along the chromosome in the wake of synapsis.
Protein: TM116_DANRE
Sequence: MDIFGENKTQMNTTTPTENWTSVYSIVRWIQMTMAVLSILGAGSIILYAAFQRLVKKPEVLPLFLLSLTDLLLALSWLCGGLLFTQSCNSYATCYNLHIVEQTLYMASFFYTLHYVWVLYTGLNGKYHRRLNGFPAEAARTRNCRCLGPVLSCLLPLLLTAPVFVAGNVFQCYTNFTQPYRCLLMHTGAVYLTSSASPELTACSIIQEYCMAIFLGTFLITIVGMSIFMGKARSLYKRVVTSQGFFGGSHWTTLRLLERRMVLYPSAFFFCWGPALLLATMMLVKPDVIEGKMGVALYILQAFTSASQGLLNCLVYGWTQKHFRSLSSSTVRDANTQTPLLRSQKPNYAALHSAASLTNFV
What are the official names of this protein?
Transmembrane protein 116.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: AROA_THEKO
Sequence: MIIRPVDEVRGELNAPPSKSYTHRAYFLALLAEGESTIENPLVCDDTLATIEAIRSFGAGVDGKTVVPPEEPSPGFVYARESGTTARFSTALAGGIGGKTLIDGARRLRERPMDGLVKALKGLGAEVDGFSLPLTVKGPVKSGRVSVDASKSSQFVSGLLLLGAEVGLKVEARNPVSKPYIEMTLRTMEAFGVEFEREGFSFEVYPGVKGTRYKVPGDYSTASFFLAAGALYGKVRVNNLLREDVQADMAFLDALEEFGARVKRGRDYVKVEGGELKAVALDCSDFPDSFPILAVVAAYAEGRSVIRARQLRFKESDRVRAMAVNLSRMGVKVRELEDGLEIEGGRPRGAKVETFNDHRIAMAMSIAALGATGPSIIEDTESVSKSHPGFFDDLRRLLE
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMD_CROS8
Sequence: MAQFYSAKRRVTTREIITVTTDGLDAFGQGVARHHGKALFIAGLLPGERAEVVLSEDKKQFARGDVKKRLSESPERETPRCPHFGVCGGCQQQHASVALQQRSKAQALCRMMKREVDEVISGPAWGYRRRARLSLNFTPRKPGLQMGFRKAGSNDLVDVHRCPVLVPRLEALLPKLRDCLSSLDGVRHLGHVELVDVTSGPLMVLRHLKPLSAADREKLECFSHSEGVALYLAPQSDTLEHLNGEMPWYESDGLRLTFSPRDFIQVNDAVNQQMVARALEWLEIQPGERVLDLFCGMGNFTLPLARRAESVVGVEGVAALVEKGDYNAGLNALKNVTFFQHNLEEDVTRQPWAQQGFDKVLLDPARAGAAGVMQHIVKLKPRRVVYVSCNPATLMRDSETLLAAGYRTVRLAMLDMFPHTGHLESMALFERD
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: C2CD5_HUMAN
Sequence: MPGKLKVKIVAGRHLPVMDRASDLTDAFVEVKFGNTTFKTDVYLKSLNPQWNSEWFKFEVDDEDLQDEPLQITVLDHDTYSANDAIGKVYIDIDPLLYSEAATVISGWFPIYDTIHGIRGEINVVVKVDLFNDLNRFRQSSCGVKFFCTTSIPKCYRAVIIHGFVEELVVNEDPEYQWIDRIRTPRASNEARQRLISLMSGELQRKIGLKVLEMRGNAVVGYLQCFDLEGESGLVVRAIGTACTLDKLSSPAAFLPACNSPSKEMKEIPFNEDPNPNTHSSGPSTPLKNQTYSFSPSKSYSRQSSSSDTDLSLTPKTGMGSGSAGKEGGPFKALLRQQTQSALEQREFPFFTLTAFPPGFLVHVGGVVSARSVKLLDRIHNPDEPETRDAWWAEIRQEIKSHAKALGCHAVVGYSESTSICEEVCILSASGTAAVLNPRFLQDGTVEGCLEQRLEENLPTRCGFCHIPYDELNMPFPAHLTYCYNCRKQKVPDVLFTTIDLPTDATVIGKGCLIQARLCRLKKKAQAEANATAISNLLPFMEYEVHTQLMNKLKLKGMNALFGLRIQITVGENMLMGLASATGVYLAALPTPGGIQIAGKTPNDGSYEQHISHMQKKINDTIAKNKELYEINPPEISEEIIGSPIPEPRQRSRLLRSQSESSDEVTELDLSHGKKDAFVLEIDDTDAMEDVHSLLTDVPPPSGFYSCNTEIMPGINNWTSEIQMFTSVRVIRLSSLNLTNQALNKNFNDLCENLLKSLYFKLRSMIPCCLCHVNFTVSLPEDELIQVTVTAVAITFDKNQALQTTKTPVEKSLQRASTDNEELLQFPLELCSDSLPSHPFPPAKAMTVEKASPVGDGNFRNRSAPPCANSTVGVVKMTPLSFIPGAKITKYLGIINMFFIRETTSLREEGGVSGFLHAFIAEVFAMVRAHVAALGGNAVVSYIMKQCVFMENPNKNQAQCLINVSGDAVVFVRESDLEVVSSQQPTTNCQSSCTEGEVTT
What is the function of this protein?
Required for insulin-stimulated glucose transport and glucose transporter SLC2A4/GLUT4 translocation from intracellular glucose storage vesicle (GSV) to the plasma membrane (PM) in adipocytes.  Binds phospholipid membranes in a calcium-dependent manner and is necessary for the optimal membrane fusion between SLC2A4/GLUT4 GSV and the PM.
What are the official names of this protein?
C2 domain-containing protein 5, C2 domain-containing phosphoprotein of 138 kDa.
Protein: PYRB_MYCUA
Sequence: MTPRHLLAAGDLSRDDAIAILDDADRFAQALVGREVKKLPTLRGRTVVTMFYENSTRTRVSFEVAGKWMSADLINVSASGSSVSKGESLRDTALTLRAAGADALIIRHPASGAARLFADWTAGQSDGGPSVINAGDGTHEHPTQALLDALTIRQRLGGIEGRRVVIVGDILHSRVARSNVTLLHTLGAEVVLVAPPTLLPVGVADWPVTVSHDLDAELPAADAVLMLRVQAERMNGGFFPSVREYSTLYGLSDRRQAMLGGHAVVLHPGPMLRGMEIASSVADSSQSAVLQQVSNGVHIRMAVLFHVLVGLESAGEEGAA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: CCD81_HUMAN
Sequence: MLDTIARALQDLGRQVLPTLPSLSQEEVSIIWGNVSEFVRRQLTLHKGVQIPAFGTFTFIRQKLEVGNNKFILIQRPVFIMVEKLVQIHGLKQNKVYTPGEIPIVPLNFVMISLEGPFNRDVVEGCVKETLLFLSRSISMKQNVEFTFKGIGVLMIRDSKVKMRFYKDFLCTMDGSGALAKALANRPGTVDSVLSSREALRKWPSSVLAFPRIELKEMENKLPMETLVEECGENRERKCKLKDQSDKEEGTRDISSPKRLRDRQALFPAKVTNVSLLEKFERSESGGKIMTPESLSYPSCLKHDSEMKPQTSPACQDHNKAGQEMCYVCLQRAQRNSLLYYSEERRREIEDERLIQQYQMLKDQEALFRHQMKSLATREQNQKNAAYNLGVAEAIRNHKNEKPEFYKSFLFDKRPLSPALNALKQEEYSRSLLKQMDNRQENEIKQRQYRELMDRLEQVQLTEELAAQRAKFLKDKMEETQCYKRALDAQIKNKPSRLPPFEPDSSEPIFGKNEGELMVEKQKREQNYMKHQLEAAANHKRKAILHQLVDQRRDLQMLQRTQREHLADRTAELERVNRVNQCLQEDWERSAAMKKQRDLEDKAFERASDKLFLLDQCEKYRRCKQCQRRTSNVGESNLWPLNKFLPGSRLLV
What are the official names of this protein?
Coiled-coil domain-containing protein 81.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: CCL2_RABIT
Sequence: MKVSATLLCLLLIAVAFSSHVLAQPDAVNSPVTCCYTFTNKTISVKRLMSYRRINSTKCPKEAVIFMTKLAKGICADPKQKWVQDAIANLDKKMQTPKTLTSYSTTQEHTTNLSSTRTPSTTTSL
What is the function of this protein?
Acts as a ligand for C-C chemokine receptor CCR2 (By similarity).  Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions (By similarity).  Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils (By similarity).  Plays an important role in mediating peripheral nerve injury-induced neuropathic pain (By similarity).  Increases NMDA-mediated synaptic transmission in both dopamine D1 and D2 receptor-containing neurons, which may be caused by MAPK/ERK-dependent phosphorylation of GRIN2B/NMDAR2B (By similarity).
What are the official names of this protein?
C-C motif chemokine 2, Monocyte chemoattractant protein 1, Monocyte chemotactic protein 1, MCP-1, Small-inducible cytokine A2.
What is the protein family that this protein belongs to?
Belongs to the intercrine beta (chemokine CC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: HTRA3_HUMAN
Sequence: MQARALLLAALAALALAREPPAAPCPARCDVSRCPSPRCPGGYVPDLCNCCLVCAASEGEPCGGPLDSPCGESLECVRGLCRCRWSHAVCGTDGHTYANVCALQAASRRALQLSGTPVRQLQKGACPLGLHQLSSPRYKFNFIADVVEKIAPAVVHIELFLRHPLFGRNVPLSSGSGFIMSEAGLIITNAHVVSSNSAAPGRQQLKVQLQNGDSYEATIKDIDKKSDIATIKIHPKKKLPVLLLGHSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQREGRELGLRDSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSDRITRFLTEFQDKQIKDWKKRFIGIRMRTITPSLVDELKASNPDFPEVSSGIYVQEVAPNSPSQRGGIQDGDIIVKVNGRPLVDSSELQEAVLTESPLLLEVRRGNDDLLFSIAPEVVM
What is the function of this protein?
Serine protease that cleaves beta-casein/CSN2 as well as several extracellular matrix (ECM) proteoglycans such as decorin/DCN, biglycan/BGN and fibronectin/FN1.  Inhibits signaling mediated by TGF-beta family proteins possibly indirectly by degradation of these ECM proteoglycans (By similarity).  May act as a tumor suppressor.  Negatively regulates, in vitro, trophoblast invasion during placental development and may be involved in the development of the placenta in vivo.  May also have a role in ovarian development, granulosa cell differentiation and luteinization (PubMed:21321049, PubMed:22229724).
What are the official names of this protein?
Serine protease HTRA3, High-temperature requirement factor A3, Pregnancy-related serine protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1C family.
What are the subcellular locations of this protein?
Secreted. Note=Secretion increased during decidualization of endometrial stromal cells.
Protein: DNPH1_METMA
Sequence: MYSKESCERCEEMEKIIPSGQGKKSIFLSGSIRGGRQLLETYRFIYDALEEAGAEVLSWHVADPELEKTESKMTEQEIYARDLGLLEKSDALIAEVTVPSTGVGYEICRALVRKIPVLCLHMPDVAVSSMVLGNPDTLMEVRSYPDKEALKEIIIDFIRAL
What is the function of this protein?
Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base.
What are the official names of this protein?
Putative 2'-deoxynucleoside 5'-phosphate N-hydrolase 1.
What is the protein family that this protein belongs to?
Belongs to the 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 family.
Protein: DAPB2_ORYSJ
Sequence: MLSLRPPCTLSPAPWRRRRTLHGAAGTPQRVSVAAPSAIVEAVSPPARFSFPILVNGCTGKMGLSVAEAVTSSGLHLVPISFSSRDTLDRTVRVGHTDVRIYGPSAREDVLSSVIDEFPDVVVVDYTAPDSVNANAELYCKLGLPFVMGTTGGDRQLLYKSVQDSNNYALISPQMGKQVVAFLAAMEIMAEQFPGAFSGYHLEVLESHQAGKLDISGTAKAVIACFEKLGVSYDMNRMVKIRDPEQQLEMVGVPEEHIEGHAFHLYHLTSPDDSVSFEFQHNVCGRSIYAEGSVDAAMFLHRKVRSNDSKRIYDMIDVLREGSMR
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
Probable 4-hydroxy-tetrahydrodipicolinate reductase 2, chloroplastic, HTPA reductase 2.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ATP25_YEAS8
Sequence: MNKFCLLPFHGKRIGVANIPFTILFKKGPCFLHSHITAVYYSTKGKNDSHEQSRVSKKSTFTPLETPWYLRIVDNEKELMEGKKNNHHTMNKELEIPKTSPNSLRKIADLLTGKLGLDDFLVFDLRKKSPNSVSAVNKLGDFMVICTARSTKHCHKSFLELNKFLKHEFCSSAYVEGNFNERQESRRKRRLARKSNLSKLLGRSSECSAKDLNSEAWYMIDCRVDGIFVNILTQRRRNELNLEELYAPENEKSKFQNIDSGNVPTISGVNEISSNNNILLGLRRLAQQRRRYSTINPNGLSNLRYFLQKEDFKGANKIIQSSSGTETHNIRTLEHVKNTLKDLVGQERKVDVVQWKSLFDEHSTFLTINQSAAYWPLRLEYAILLNKADPQFYSDRVFLKDYLLLKKSLGQELIREDLIALLEMVLKTQHSSHSYFNLVKQNRVIIRALNLFKGLQTEDDGSVVYDEEVISLLLNSMVADERVKLRSLYETIDHIFQTFGDKLTSGMIVSILQNLAKIKDWNKLLQVWEAITPTEGEGQDKRPWNEFINVINQSGDSHVISKIVNNGHLLWIRRLNVNVTPELCNSIKALLKTAGMENSTLEEFLVRGTNNQ
What is the function of this protein?
mRNA stabilization factor specific for the 0. 95 kb OLI1 mRNA.  Also involved in OLI1 ring formation (By similarity).
What are the official names of this protein?
ATPase synthesis protein 25, mitochondrial, OLI1 mRNA stabilization factor.
What is the protein family that this protein belongs to?
Belongs to the ATP25 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: Y872_HAEIN
Sequence: MNRLFFSKIALWLLDFLTFNISFLLSLFVISYYHNGYEKYLPIYEIDDRTYIHAVLAGICVGWFAIRLRHYTYRKPFWFELKEIFRTLIIFAIFELAIVAFPKLYFSRYLWALTWGITFLLFPLARVLVKKFLIKSGWFLRDTIMIGSGDNAFDVYNALRDEPYLGFQVTHFISVSNISNNVKELNIPILNSMSSWTSVTKKTDQFIIALEDDEEVDRNNWLRYFSTNGYRSVSVIPTLRGLPLYNTDMSFMFSHEIMLLQMNNNLAKLSSRILKRTMDIVVGSLAIIIFSPVLLYLYFAVKKDGGNAIYGHPRIGRNGKTFNCLKFRTMAVNSKEVLDELLRTDPEARAEWEKDFKLKNDPRITKIGAFIRKTSLDELPQLFNVLKGEMSLVGPRPIVIDELERYEENVDYYLMARPGMTGLWQVSGRNNIDYNTRVYFDSWYVKNWSLWNDIAILFKTMNVVLNRDGAY
What is the function of this protein?
May function as a sugar transferase.
What are the official names of this protein?
Uncharacterized sugar transferase HI_0872.
What is the protein family that this protein belongs to?
Belongs to the bacterial sugar transferase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TORD_VIBVY
Sequence: MMQEIKAFNEKRAEIYWWLSSLFAKELTQEELDKYQSMEIRAFLTGLAENDALRPSVNAFVDALNRLVDRQDAQLELAADFCDLFLKTAKHGALPYASIYLTKDGLLNGEPAQKMDAWLKKHGVQVNQQLNEPADHLAIMLDFLGNLIIRSNELEQDRHMEEAFIEQNAFIQEMLLSWLPSFSQRAAEYDEFGFYNSAIKLLVAFCMLDSDYLVG
What is the function of this protein?
Involved in the biogenesis of TorA.  Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor.
What are the official names of this protein?
Chaperone protein TorD.
What is the protein family that this protein belongs to?
Belongs to the TorD/DmsD family. TorD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRC_SYNP6
Sequence: MIAATPMPLLKQPDRLEARLRELPAEPGVYFMRDASDRILYIGKSKKLRSRVRSYFRDLERLNPRINLMVRQVCEIEIIVTDTEAEALALEANLIKQHQPHFNVLLKDDKKYPYLCITWSDDYPRIFITRKRRLGNSRDRYYGPYVDTRLLRHTLFLVKRLFPLRQRPQPLFKDRTCLNYDIGRCPGVCQSLIRPDDYRKTLQKVAMIFQGRSSELVELLEAQMLQAAENLEFEKAAKIRDQIRGLEGLGAEQKVQLPDDRISRDAIALAMDEQHACIQLFQIRAGKLVGRLGFVADAQSGSAAAIAQRVLEEHYASVDSVEIPQEVLVQHDLPEAELLEVWLSERRGRKVEILSPQRQIKADLIAMVERNAEYELARTQQSAERHTASLIDLADLLDLPELPRRIEGYDISHIQGSDAVASQVVFIDGLPAKQHYRRYKIRNPEVRAGHSDDFASLAEVLHRRFRKFAEAKARGESLAPSEQRQGSLLRPDDLADFPDLVMIDGGKGQLSAVVEVLRNLNLLEDVKLCSLAKKREEIFLPGASDPLPTDAEQPGVQLLRRLRDEAHRFAVSFHRQKRTERMRRSRLDDIPGLGHKRQKELLAHFRSIDYLRLATPEQIAEVPGIGAVLAQQIWGYFHPSETA
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAH5A_RAT
Sequence: MLRAKMLGRGPYKPLAILRHMGPLCATRPQHWRFQHSYAEKHSNCARHPLWTGPVSSPGGTQQSPINIQWTDSVYDPKLAPLRVSYDAASCRYLWNTGYFFQVEFDDSCEESGISGGPLGNHYRLKQFHFHWGATDEWGSEHMVDGHAYPAELHLVHWNSMKYENYKKATTGENGLAVIGVFLKLGAHHEALQRLVDILPEVRHKDTQVTMGPFDPSCLLPACRDYWTYPGSLTTPPLAESVTWIVHKMPIEVSPSQLSTFRTLLFSGRGEDEEVMVNNFRPLQPLRGRNVRSSFQVPRVGTKS
What is the function of this protein?
Mitochondrial carbonic anhydrase that catalyzes the reversible conversion of carbon dioxide to bicarbonate/HCO3 (PubMed:7937950).  Mitochondria are impermeable to HCO3, and thus this intramitochondrial carbonic anhydrase is pivotal in providing HCO3 for multiple mitochondrial enzymes that catalyze the formation of essential metabolites of intermediary metabolism in the urea and Krebs cycles (By similarity).
What are the official names of this protein?
Carbonic anhydrase 5A, mitochondrial, Carbonate dehydratase VA, Carbonic anhydrase VA, CA-VA.
What is the protein family that this protein belongs to?
Belongs to the alpha-carbonic anhydrase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SURE_VIBCH
Sequence: MKILLSNDDGVYAQGIHALADALRDLAEIVIVAPDRNRSGASNSLTLEHPLRVSQIAENTYSVQGTPTDCVHFALNELMKDALPDLVLSGINHGANLGDDVLYSGTVAAAMEGHFLGVQSIAFSLAGTTHFASAAHFVRQLVEQHLANPIPTNRLLNVNIPDRPLELIQGIEVTRLGARHHAESMIKQKDPRGHDIYWLGPPGKEQDAGPGTDFHAIERGWVSLTPLQVDLTAHESLRSMDHWLKEKVNG
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPD_ACIF2
Sequence: MADLITVARPYAEALYGLAKESGQEQAWADALQALAAMIADVQAQAFLTDPERADAEKVSLLSAVPVAVDVKAWKAFLALLIHNDRWPATAEIGTLFADAMRRAEGVVDVLVTSAIALDAGQKTAVQSALERRFAGHKVAFREAVDAALIGGLVIHTGDLTIDASVRGQVQQLARTLRS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.