PharMolix/UniProtQA huggingface dataset:
Protein: SYR_CHLPN
Sequence: MSTLLSILSVICSQAIAKAFPNLEDWAPEITPSTKEHFGHYQCNDAMKLARVLKKAPRAIAEAIVAELPQEPFSLIEIAGAGFINFTFSPVFLNQQLEHFKDALKLGFQVSQPKKIIIDFSSPNIAKDMHVGHLRSTIIGDSLARIFSYVGHDVLRLNHIGDWGTAFGMLITYLQENPCDYSDLEDLTSLYKKAYVCFTNDEEFKKRSQQNVVALQAKDPQAIAIWEKICETSEKAFQKIYDILDIVVEKRGESFYNPFLPEIIEDLEKKGLLTVSNDAKCVFHEAFSIPFMVQKSDGGYNYATTDLAAMRYRIEEDHADKIIIVTDLGQSLHFQLLEATAIAAGYLQPGIFSHVGFGLVLDPQGKKLKTRSGENVKLRELLDTAIEKAEEALREHRPELTDEAIQERAPVIGINAIKYSDLSSHRTSDYVFSFEKMLRFEGNTAMFLLYAYVRIQGIKRRLGISQLSLEGPPEIQEPAEELLALTLLRFPEALESTIKELCPHFLTDYLYNLTHKFNGFFRDSHIQDSPYAKSRLFLCALAEQVLATGMHLLGLKTLERL
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU_RICAH
Sequence: MAKAKFERTKPHVNIGTIGHVDHGKTSLTAAITTVLAKTGGAKATAYDQIDAAPEEKERGITISTAHVEYETKNRHYAHVDCPGHADYIKNMITGAAQMDGAILVVSAADGPMLQTREHILLAKQVGVPAMVVFLNKVDVVDDPALLELVEMEVRDLLLQYGFPAYEVPIIKGSALQALAGKPEGEKAINELMDAVDNYIPHPVRATDKPFLMPIEDVFSISGRGTVVTGRVESGIIKVGEEVEIVGLKETQKTTCTGVEMFRKLLDEGQAGDNVGILLRGTKREEVERGQVLAKPGSIKPHDQFEAEVYVLSKEEGGRHTPFTNDYRPQFYFRTTDVTGTIKLPADKQMVMPGDNATTFTVELIKPIAMQQGSKFSIREGGKTVGAGVVTKINN
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_RHOPT
Sequence: MIGALARKLFGSANDRRVKGYQTRVAAINALEPEVAALSDEALRARTAEFRAELAAGKTLDDLLVPAFATVREAAKRTLGQRHFDVQLIGGMVLHEGDIAEMKTGEGKTLVATLAVYLNALAGKGVHVVTVNDYLAKRDSGWMGQIYGFLGMTTGVIVHGLDDAQRQAAYACDITYGTNNEYGFDYLRDNMKYRLEDMVQRGHNFAIVDEVDSILIDEARTPLIISGPLDDRSDFYNTIDTFIPRLDKSDYDVDEKQRTVTLTEAGMEKIETLLRDAGQLRGESLYDVENVSVVHHVNQALRAHALFQRDKDYIVRNDEVVIIDEFTGRMMQGRRYSEGLHQALEAKEHVTVQPENQTLASITFQNYFRMYDKLAGMTGTASTEADEFFDIYKLEVVEIPTNLPIARLDEDDEVYRTQQEKYAAILAEVERANKRMQPVLVGTASIEKSEVLAEYLKKNGYKQIDFTDPKGMDKLYAAARAGKPAKLFAVLNARFHEQEAYIVAEAGVPGAITIATNMAGRGTDIKLGGSLEMRIQQEAAHITDEAERAAKITEIKADIERFRDIVLKAEDEIEIEPAKGNKPAKTAKRPGGLYIIGSERHESRRIDNQLRGRSGRQGDPGRSKFFLSLEDDLMRIFGSDKLDTMLTRLGLKEGEAIIHPWINKALEKAQQKVEARNFDIRKNLLKFDDVQNDQRKVIFDQRIELMKEDSVAETVTDMRHTYIEDLVAKYVPEHAYAEQWDVAGLKAEVERVVGLDIPVDEWAKEEGIADEELITRLERVFDEHMAAKVGQWGSDVMRYAEKSILLQTLDHLWREHLVMLDHLRQVIGLRGYGQRDPLQEYKSEAFNLFQEMSSHLREAVTAQLMRVEIIPPDQPQELPPMEVHKMDPDTGQDEMALANVTLAPAQTTDKADRDPNKPETWGKVGRNEDCPCGSGKKYKHCHGRYA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: GCR_SAGOE
Sequence: MDSKESLTPGKEENPSSVLTQERGNVMDFCKILRGGATLKVSVSSTSLAAASQSDSKQQRLLVDFPKGSVSNAQQPDLSKAVSLSMGLYMGETETKVMGNDLGFPQQGQISLSSGETDLQLLEESIANLNRSTSVPENPKSSASSSVSAAPKEKEFPKTHSDVSSEQQNLKGQTGTNGGNAKLCTADQSTFDILQDLEFSSGSPGKETNQSPWRSDLLIDENCLLSPLAGEEDSFLLEGNSNEDCKPLILPDTKPKIKDNGDLVLSSSSNVTLPQVKTEKEDFIELCTPGVIKQEKLSTVYCQASFPGANIIGNKMSAISIHGVSTSGGQMYHYDMNTASLSQQQDQKPIFNVIPPIPVGSENWNRCQGSGDDNLTSLGTLNFPGRTVFSNGYSSPSMRPDVSSPPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKKKIKGIQQATTGVSQETSENPANKTIVPATLPQLTPTLVSLLEVIEPEVLYAGYDSTVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQASSNLLCFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIEFPEMLAEIITNQLPKYSNGNIRKLLFHQK
What is the function of this protein?
Receptor for glucocorticoids (GC).  Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors.  Affects inflammatory responses, cellular proliferation and differentiation in target tissues.  Involved in chromatin remodeling.  Plays a role in rapid mRNA degradation by binding to the 5' UTR of target mRNAs and interacting with PNRC2 in a ligand-dependent manner which recruits the RNA helicase UPF1 and the mRNA-decapping enzyme DCP1A, leading to RNA decay.  Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth.  Mediates glucocorticoid-induced apoptosis.  Promotes accurate chromosome segregation during mitosis.  May act as a tumor suppressor.  May play a negative role in adipogenesis through the regulation of lipolytic and antilipogenic gene expression.
What are the official names of this protein?
Glucocorticoid receptor, GR, Nuclear receptor subfamily 3 group C member 1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=After ligand activation, translocates from the cytoplasm to the nucleus (By similarity). In the presence of NR1D1 shows a time- dependent subcellular localization, localizing to the cytoplasm at ZT8 and to the nucleus at ZT20 (By similarity). Lacks this diurnal pattern of localization in the absence of NR1D1, localizing to both nucleus and the cytoplasm at ZT8 and ZT20 (By similarity).
Protein: PYRE_CAMHC
Sequence: MDIEKIYKEHGAFLEGHFLLSSGNHSQFYLQSAKILEFPWIAGELANELFNVIKNAGIEFDSVCSPALGGILAGYELAKSAHKRFIFTERVDKKMTLRRGFSVSKGEKFIVCEDIITTGGSALESAKIIESLGGEVVAFAALANRGFCAVQNLGNERKESCKLPFNKPLFTLGNFEFDIYEPENCPLCKTGSVAIKPGSRGN
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: RUVA_LACLS
Sequence: MFEYLNGKLVKISPTNIVIDLSGIGYLISVANPYAWSALMNTEVKIYVHQVIREDAHSLYGFVNESEKALFLRLISVSGIGPKSALAIIAAADNEGLINAIDNSDIKYLTKFPGVGKKTAMQMVLDLAGKFDATGAVGISLLDAAPAGNLALEEAIEALQALGYKATELKKIEKKLEQEAGLTSEEYIKSALKLMMK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: MO2B1_AEDAE
Sequence: MNYLKLTFDKLEVGEINDLVAHESCGAISLFVGTTRDNFDGKTVVLLEYEAYEAMALKTMNQICEELRARWPDIKHIGIHHRLGTVPVKEASVVIAVSSPHRKSSLEAVHFAIDELKKSVPVWKKEQYADGEGCSEWKENKECSWSKSHRDNHIL
What is the function of this protein?
Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin.  Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
What are the official names of this protein?
Molybdopterin synthase catalytic subunit 1, Molybdenum cofactor synthesis protein 2 large subunit 1, Molybdenum cofactor synthesis protein 2B 1, MOCS2B 1.
What is the protein family that this protein belongs to?
Belongs to the MoaE family. MOCS2B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHED2_METAC
Sequence: MSDDILFVSNGNGKAIFLTSRAVLVKSFCSLSKTCSFKDSCQSCEIVDAAKSYLMGKKSDLNVKSLDGELSAGIGEYKIGKNVLLKVMGLGSCIGVILSDVSTGICGIAHVLLPGASNSGEAKYAETAIENMFEDMIRMGARKNRITAKFAGGAQVFKHMSLDILKIGDRNAISVEETLVKRNIPILAKDVGGEVGRNVIFNPVDGSMIVKYTKGEVLWL
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD 2.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: RLMH_SHIFL
Sequence: MKLQLVAVGTKMPDWVQTGFTEYLRRFPKDMPFELIEIPAGKRGKNADIKRILDKEGEQMLAAAGKNRIVTLDIPGKPWDTPQLAAELERWKLDGRDVSLLIGGPEGLSPACKAAAEQSWSLSALTLPHPLVRVLVAESLYRAWSITTNHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_YERPB
Sequence: MERYQQLFKQLAAKKEGAFVPFVQLGDPSPAMSLNIIDTLIAAGADALELGIPFSDPLADGPTIQNAALRAFAAGVTPAICFEILAEIRQKHPTIPIGLLMYANLVFHNGIDHFYQRCAEVGVDSVLIADVPFEESAPFRAAALRHGIAPIFICPPNADDDLLREIASHGRGYTYLLSRAGVTGAENHGQLPLNHLVDKLREYNAAPALQGFGISEPAQVKASLAAGAAGAISGSAIVKIIEKNVAQPVEMLVQLTRFVTEMKAATRS
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: ILVC_BRUSI
Sequence: MRVYYDRDADVNLIKSKKVVIVGYGSQGRAHALNLKDSGAANVRVALREGSATVQKAQADGFEVMNVADAAKWADLMMMATPDELQADIYRDYIHNNLRDGAAIAFAHGLNVHFGLIEPKKTVDVVMIAPKGPGHTVRGEYQKGGGVPCLIAIHQDASGNAHDLALSYASGVGGGRSGVIETTFKEECETDLFGEQAVLCGGVVELIRTGFEVLVEAGYAPEMAYFECLNEMKLIVDLIYEGGIANMNYSISNTAEWGEYVTGPRIITAETKAEMKRVLKDIQTGKFTSDWMQEWKAGAARFKGIRRLNDAHQIEEVGGKLRAMMPWIEKNKLVDKARN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: FKBP2_KLULA
Sequence: MKFTTGLSVLLFFVLQVFAEKLTELVVGVTKEPVDCKIKASKGDVVSVHYTGKLRDSGEIFDSSYNRGVPIQFKLGYSQVISGWDQGILGMCIGEGRTLHIPSELGYGSRGAGSVIPPDADLIFETELVDIQREAVDDEL
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
FK506-binding protein 2, Peptidyl-prolyl cis-trans isomerase, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. FKBP2 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: Y1656_BRUSU
Sequence: MLYYVLVFLVVALVAGALGFGGIAGASAGIAQILFFVFLALLVISLIASAIRKA
What are the official names of this protein?
UPF0391 membrane protein BR1656/BS1330_I1650.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ODO1_ECO57
Sequence: MQNSALKAWLDSSYLSGANQSWIEQLYEDFLTDPDSVDANWRSTFQQLPGTGVKPDQFHSQTREYFRRLAKDASRYSSTISDPDTNVKQVKVLQLINAYRFRGHQHANLDPLGLWQQDKVADLDPSFHDLTEADFQETFNVGSFASGKETMKLGELLEALKQTYCGPIGAEYMHITSTEEKRWIQQRIESGRATFNSEEKKRFLSELTAAEGLERYLGAKFPGAKRFSLEGGDALIPMLKEMIRHAGNSGTREVVLGMAHRGRLNVLVNVLGKKPQDLFDEFAGKHKEHLGTGDVKYHMGFSSDFQTDGGLVHLALAFNPSHLEIVSPVVIGSVRARLDRLDEPSSNKVLPITIHGDAAVTGQGVVQETLNMSKARGYEVGGTVRIVINNQVGFTTSNPLDARSTPYCTDIGKMVQAPIFHVNADDPEAVAFVTRLALDFRNTFKRDVFIDLVCYRRHGHNEADEPSATQPLMYQKIKKHPTPRKIYADKLEQEKVATLEDATEMVNLYRDALDAGDCVVAEWRPMNMHSFTWSPYLNHEWDEEYPNKVEMKRLQELAKRISTVPEAVEMQSRVAKIYGDRQAMAAGEKLFDWGGAENLAYATLVDEGIPVRLSGEDSGRGTFFHRHAVIHNQSNGSTYTPLQHIHNGQGAFRVWDSVLSEEAVLAFEYGYATAEPRTLTIWEAQFGDFANGAQVVIDQFISSGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQLCAEQNMQVCVPSTPAQVYHMLRRQALRGMRRPLVVMSPKSLLRHPLAVSSLEELANGTFLPAIGEIDELDPKGVKRVVMCSGKVYYDLLEQRRKNNQHDVAIVRIEQLYPFPHKAMQEVLQQFAHVKDFVWCQEEPLNQGAWYCSQHHFREVIPFGASLRYAGRPASASPAVGYMSVHQKQQQDLVNDALNVE
What is the function of this protein?
E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
What are the official names of this protein?
2-oxoglutarate dehydrogenase E1 component, Alpha-ketoglutarate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the alpha-ketoglutarate dehydrogenase family.
Protein: MCK1_YEAST
Sequence: MSTEEQNGVPLQRGSEFIADDVTSNKSNNTRRMLVKEYRKIGRGAFGTVVQAYLTQDKKNWLGPFAIKKVPAHTEYKSRELQILRIADHPNIVKLQYFFTHLSPQDNKVYQHLAMECLPETLQIEINRYVTNKLEMPLKHIRLYTYQIARGMLYLHGLGVCHRDIKPSNVLVDPETGVLKICDFGSAKKLEHNQPSISYICSRFYRAPELIIGCTQYTTQIDIWGLGCVMGEMLIGKAIFQGQEPLLQLREIAKLLGPPDKRFIFFSNPAYDGPLFSKPLFSGSSQQRFEKYFGHSGPDGIDLLMKILVYEPQQRLSPRRILAHQFFNELRNDDTFLPRGFTEPIKLPNLFDFNDFELQILGEFADKIKPTKVAE
What is the function of this protein?
May be an autophosphorylating tyrosine kinase, a bifunctional (serine/tyrosine-specific) protein kinase, or a serine kinase that is a substrate for an associated tyrosine kinase.  MCK1 is a transcriptional activator of IME1, it stimulates spore maturation, and play a positive regulatory role in both mitotic centromere function and activation of early meiotic gene expression.
What are the official names of this protein?
Protein kinase MCK1, Meiosis and centromere regulatory kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: MUTS_BORA1
Sequence: MSTVDSSSHTPMMQQYLRLKAEAGPLLLFYRMGDFYEMFYEDAEKAARLLNVTLTKRGTSNGAPIPMAGVPVHAMEQYLARLVALGESVAICEQIGDPAAAKGPVERRIVRIVTPGTLTDDALLPAKADRALAAVCLSGKRDPRAGIAWLNLASGEFHVTECAPAQLDSELHRIGPAELVYADSTELDITYSGARSRVPDWHFEADGARSHLLTHFQTDSLAGFDIEDMPVAVCAAGALLRYAARTQSQALAHVQTISAERAGMYVLMDPVTRRNLELTQTLSGEEAPTLFSLLDDCRTPMGSRLLRRWLHHPLRENAPVAARQQAIATLLSARLDMAQTFGAAGLLETLRSALGLFPDIERIAARLALRSVRPRELASLRDALATLPQLQTLVAPLSASPRLAELATQLTLDPAIADLLSRAIAQEPALAIRDGGVIASGFDADLDELRLLAADSGEFLVQLEARERERTGISNLRVEFNRVHGFYIEVSKGQTDKVPEDYRRRQTLKNAERYITPELKSWEDKVLSAQDRALAREKWLFEQVLDALSAYVRPLSDAAAALAELDALGSLAEHARRHEWVAPDLLESAEIDIDAGRHPVVEHAIERFTPNHCRLDATRRMLLITGPNMGGKSTYMRQVALIALLARTGSFVPARRARVGKIDRIFTRIGAADDLAGGRSTFMMEMTEAAAILAASTSNSLVLMDEIGRGTSTYDGLALAWAIAQRLITHNRALTLFATHYFELTRLPSEQATAANVHLAAAESAGGIVFLHEVREGPASRSYGIQVAQRAGIPAAVIRHATRELERLEAQGAPTPQLGLFAAALDAEAQTQAQADHDAENAALLALHEALSGIDPDSLTPREALEALYRLKALQ
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: MRGRH_RAT
Sequence: MEPLATTLCPQECTQTTRNETPNETTWSSEHVTKYTYISISLVICSLGLVGNGLLIWFLIFCIKRKPFTIYILHLAFADFMVLLCSSIIQLVNTFHIYDSTLVSYAVLFMIFGYNTGLHLLTAISVERCLSVLYPIWYHCRRPKHQSTVACTLLWALSVLVSGLENFFCILEVKPQFPECRYVYIFSCTLTFLVFVPLMVFSNLILFIQVCCNLKPRQPAKLYVIIMATVILFLVFAMPMKVLLIIGYYSNSTDASVWKSLPYLNMLSTINCSINPIVYFVVGSLRRKRSRKSLKEALQKVFEEKPVVASRENEVQFSLPL
What is the function of this protein?
Orphan receptor.  May regulate nociceptor function and/or development, including the sensation or modulation of pain.
What are the official names of this protein?
Mas-related G-protein coupled receptor member H.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Mas subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LPXB_SALAR
Sequence: MAAQRPLTIALVAGETSGDILGAGLIRALKARVPNARFVGVAGPRMQAEGCEAWYEMEELAVMGIVEVLGRLRRLLHIRADLTRRFTALKPDVFVGIDAPDFNITLEGNLKKQGIKTIHYVSPSVWAWRQKRVFKIGRSTHMVLAFLPFEKAFYDKFNVPCRFIGHTMADAMPLDPNKNTARDVLGIPHDAHCLALLPGSRGAEVEMLSADFLKTAQLLRQHYPDLEVVVPLVNAKRREQFEKIKAEIAPDLAVHLLDGMGREAMVASDAALLASGTAALECMLAKCPMVVGYRMKPFTFWLAKRLVKTEYVSLPNLLAGRELVKELLQEECEPQKLAEALLPLLANGKTSHVMHDTFRELHQQIRCNADEQAADAVLELAQ
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: RL25_RICBR
Sequence: MSEILELEAKSRNEFGTGAARALRREGRVPAIIYGAKKTPVSISLEEKEITKYYRKPAFISQLINLTIEGTQYKVLPKAVELHPVTDIVRHVDFVFLEDKTQKMEVPVVYEGKERALGVKRGGYFNIVKRRVTLLCDVNNIPRNVTIDVTNMPIATSLKSSKVKLPEGCSFTTKKEFVLATIIGRRGAKTEAEGEQTAEAAK
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: ALG10_USTMA
Sequence: MATSSSDRWPIPLKQHIPTLIFITVTVLTSNLVSRTQPTAYLDEIFHIPQAQQFCSALSSTSLFSAQQVWRQLTSVRYDAQLTTPPGMYAISVGMAKVLPGWECKDVVWLRSTNLVLLLTLPVLVARILGQIEEQARIASAAEDYSPSKTITQNLGKEITRHEIEMLQAKAKLQLPPTPSASHDDLAHIEPPTISIAQAALPAPTGSAAPLLRALKQREASAYTMALACTICFLPPLWFFGFLYYTDLASTWLVLAMLSLYNDLNTSNAHVAPTITGLLIALTSILAVAVRQTNIVWIGFAAAQATLSRVGKHVSHTQQGSDPVTQAIGMVKGAFGDNKKGWWTAVAINAAPMVPVLAVCVLFLRWNGSIVLGEKAAHQVALHLPQMGYFVAFALGFGLFPLLFSLQSMSHKAQDQGPSSSTLATFTHSVRSAVSALIDSTIASPGCILALAAALAGFYIAVDRFTIEHAYMLADNRHYTFYIWRKYRSSYAIPALDGMTIEPKLAVVPLFALALIAWSRALTHHAVNKRTGALFSLLFWMATAAVLVPTPLIEPRYFLMAYLLLRIYSHPYAPCEKQEKSAQLKWIYLALEAATYAAVNVITVGLFVNRPFQWPSHAVDVSRNEHTTMRFLW
What is the function of this protein?
Adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation.  Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol.
What are the official names of this protein?
Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase, Alpha-1,2-glucosyltransferase ALG10-A, Alpha-2-glucosyltransferase ALG10, Asparagine-linked glycosylation protein 10, Dolichyl-phosphoglucose-dependent glucosyltransferase ALG10.
What is the protein family that this protein belongs to?
Belongs to the ALG10 glucosyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MRAP_HUMAN
Sequence: MANGTNASAPYYSYEYYLDYLDLIPVDEKKLKAHKHSIVIAFWVSLAAFVVLLFLILLYMSWSASPQMRNSPKHHQTCPWSHGLNLHLCIQKCLPCHREPLATSQAQASSVEPGSRTGPDQPLRQESSSTLPLGGFQTHPTLLWELTLNGGPLVRSKPSEPPPGDRTSQLQS
What is the function of this protein?
Modulator of melanocortin receptors (MC1R, MC2R, MC3R, MC4R and MC5R).  Acts by increasing ligand-sensitivity of melanocortin receptors and enhancing generation of cAMP by the receptors.  Required both for MC2R trafficking to the cell surface of adrenal cells and for signaling in response to corticotropin (ACTH).  May be involved in the intracellular trafficking pathways in adipocyte cells.
What are the official names of this protein?
Melanocortin-2 receptor accessory protein, B27, Fat cell-specific low molecular weight protein, Fat tissue-specific low MW protein.
What is the protein family that this protein belongs to?
Belongs to the MRAP family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein. Note=The formation of antiparallel homo- and heterodimers suggest that N- and C-terminus can both localize in the cytoplasmic and extracellular parts, depending on the context (PubMed:20371771). Upon insulin stimulation, it is redistributed into spotty structures throughout the cytoplasm.
Protein: TATD_MUSP7
Sequence: MFDIGVNLTSSQFESDRDAVISRARREGVTGMLLTGTGIEESRHALRLAEGAPGYCWSTAGIHPHEASTWTDAAALSIRQLAVHPQVVAIGECGLDFNRNFSTPSEQERAFSAQLAIAADLGMPVFMHCREAHSRFMMLLRPWLEKLPAAVLHCFTGTRDELDECLQAGLSIGITGWVCDERRGLALRALLEYIPDDRLLLETDAPYLLPRDLHPKPTSRRNEPCFLPHIVRQVAAWRKQDAVALGRVVDDNARRIFRLGQKGE
What is the function of this protein?
3'-5' exonuclease that prefers single-stranded DNA and RNA.  May play a role in the H(2)O(2)-induced DNA damage repair.
What are the official names of this protein?
3'-5' ssDNA/RNA exonuclease TatD, DNase TatD.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. TatD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAC_CUSRE
Sequence: MSHSVKIYDTCIGCTQCVRACPTDVLEMIPWDRCKAKQIASAPRTEDCVGCKRCESACPTDFLSVRVYLGHETTRSMGLTY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Plastid thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: Y7842_BRADU
Sequence: MTPTLDTKYVFTITARIGDVVTAGETGIGVRRIIPIIGGEVTGAVTGKVLPFGADFQTIRPNELIDLEAKYAFETADGAIVYVENKGIRFGPVELLQELKRGEPVDPKLIYFRTVPRFETGHEKYRWLMEHIFVASAARHADRVVIDVHQVM
What are the official names of this protein?
UPF0311 protein blr7842.
What is the protein family that this protein belongs to?
Belongs to the UPF0311 family.
Protein: RSI1_SOLLC
Sequence: MAKSGYNASFLLLISMFLILLTFSNVVEGYNKLRPTDCKPRCTYRCSATSHKKPCMFFCQKCCATCLCVPKGVYGNKQSCPCYNNWKTQEGKPKCP
What are the official names of this protein?
Protein RSI-1, TR132.
What is the protein family that this protein belongs to?
Belongs to the GASA family.
What are the subcellular locations of this protein?
Secreted.