PharMolix/UniProtQA huggingface dataset:
Protein: NETR_PONPY
Sequence: MTLARFVLALVLGALPEVVSFDSVLNDSLHHRHRHRHSPPPGLQYPYYLPTQQRPPRTRPPPPLPRFPRPPRALPAQRPHALQAGHTPRPHPWGCPAGEPWVSVTDFGAPCLQWAEVPPFLERSPPASWAQLRGQRHNFCRSPDGAGRPWCFYGDARGKVDWGYCDCRHGSVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLGLIPIYWSNVRCQGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFPIIRLVGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLSLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKFGKQASANHFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRLSLGFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVRCTGNERSLADCIKQDIGRHNCRHSEDAGVICDYFGKKASGNSNKESLSSVCGLRLLHRRQKRIIGGKNSLRGGWPWQVSLRLKSSHGDGRLLCGATLLSSCWVLTAAHCFKRYGNSTRNYAVRVGDYHTLVPEEFEEEVGVQQIVIHREYRPDSSDYDIALVRLQGPEEQCARFSSHVLPACLPLWRERPQKTASNCYITGWGDTGRAYSRTLQQAAIPLLPKRFCEERYKGXFTGRMLCAGNLHEHKRVDSCQGDSGGPLMCERPGESWVVYGVTSWGYGCGVKDSPGVYTKVSAFVPWIKSVTKL
What is the function of this protein?
Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations.
What are the official names of this protein?
Neurotrypsin, Serine protease 12.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: LPOA_PHOPR
Sequence: MNSMLNFTHKRKSVSRLLAPVALAVILAGCSSSNQQQASASNITAIATDTSANYLIKAESSDGIESIDWNILALKALIKEGQWTQADNQSKRLSRMSLSPIQMAEWQLARATLRYQQGQLQEALNTLNFQPWWPLPDNQYKRYFMLRAELLGQLGQHSKAARQRTMLDQYLPSNQKNANWQNLWQDLSSYNNSQLQSVSLKEDETVLRGWIQLSILKNTYSQRPVRLKSAVDEWLSMNPYHPAHQYLPTELEAIMSMEVAQLDNVALLLPLTGRFESQGKAVRDGFINAMLDDTSRDTDTELTVFDTEAESMTAIMAKLQANGTQFVIGPLRKEKVTAFQQSNTSQINLLALNQPEQLDVSQTQSCYFSLSPEQEAEQAAQHLFAKGHQYPLVLAPKSKFGQRMTDAFNEQWQQLTGRNADIDTFGSRKQIQQQISRIFGLNDSQARISQMNQLTGVKLESQQRSRRDTDAVYLIANKSELTLLKPFIEVAINPEVKPPKLYASSRGNPNANSDNSELRGIEFSDIPLIINPELSFMERFDSLWPNESNTSIRLHAFGMDAYKMVNELPQLRVVDNYTVQGMTGQLGIDNQCVVQREMDWAVFTSDGITPAAE
What is the function of this protein?
Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a).
What are the official names of this protein?
Penicillin-binding protein activator LpoA, PBP activator LpoA.
What is the protein family that this protein belongs to?
Belongs to the LpoA family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor; Periplasmic side.
Protein: Y1470_STRPD
Sequence: MTAILITGYRSFEIGIFDHKDPRVSIIKQAIRKDLIGYLENGVDWFIFTGNLGFEQWALEVANELKEEYPLQIATIFLFETHGDKWNEKNQEVLSQFRAVDFVKYYFPNYEQPTQFSQYYQFLLEKTEGAYVFYDTENETNLKYFLKKAKDMPYYQLLLLTFDRLNDMSQS
What are the official names of this protein?
UPF0398 protein MGAS10270_Spy1470.
What is the protein family that this protein belongs to?
Belongs to the UPF0398 family.
Protein: CRNA_EMENI
Sequence: MDFAKLLVASPEVNPNNRKALTIPVLNPFNTYGRVFFFSWFGFMLAFLSWYAFPPLLTVTIRDDLDMSQTQIANSNIIALLATLLVRLICGPLCDRFGPRLVFIGLLLVGSIPTAMAGLVTSPQGLIALRFFIGILGGTFVPCQVWCTGFFDKSIVGTANSLAAGLGNAGGGITYFVMPAIFDSLIRDQGLPAHKAWRVAYIVPFILIVAAALGMLFTCDDTPTGKWSERHIWMKEDTQTASKGNIVDLSSGAQSSRPSGPPSIIAYAIPDVEKKGTETPLEPQSQAIGQFDAFRANAVASPSRKEAFNVIFSLATMAVAVPYACSFGSELAINSILGDYYDKNFPYMGQTQTGKWAAMFGFLNIVCRPAGGFLADFLYRKTNTPWAKKLLLSFLGVVMGAFMIAMGFSDPKSEATMFGLTAGLAFFLESCNGAIFSLVPHVHPYANGIVSGMVGGFGNLGGIIFAIIFRYSHHDYARGIWILGVISMAVFISVSWVRPVPKSQMRE
What is the function of this protein?
Permease for nitrate uptake.
What are the official names of this protein?
Nitrate transporter, Nitrate permease.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RIMM_STRZT
Sequence: MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEKDQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYHEIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRVDVEILEGLDDED
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y452_METJA
Sequence: MMSVLVIVGCPEPPALIPSVLYLTNQLKKKGFNVIIAANPAALKLLEVADDDKYYLKGVGAVDIDGGLRGIEGINKIISFVHNDGGVSYTVTYKAKYNKPTYAIVFGRQINKDYVETLKNSNIGVYTARAFHNPMPIVNRIKEILANL
What are the official names of this protein?
Uncharacterized protein MJ0452.
Protein: RL15_BORBZ
Sequence: MFNLLKPKGASKRRKIVGRGPGSGLGKTSGRGQKGQKARNTSPRLGFEGGQTPLYRRLPRKGFSNSDYKLEYAIVNLGDIDKKFKDGQVVNYDTLLENKLIKKKNKKIKILSNGKLTKKVSFEVSKISKSAESLVIKIGCTIQLV
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: AROQ_VIBVY
Sequence: MSAKSRILVLNGPNINLLGLREPGHYGHQTLPQIVDTLTQQAQTAGIELEHLQSNREYELIEAIHAAHGNVDFIIINPAAFTHTSVALRDALLGVAIPFIEVHLSNVHAREPFRHHSYLSDKALGVICGLGAQGYEFALSAAIARLQAK
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: RL7_BURO0
Sequence: MAIAKEDILAAVEGMTVLELNELVKAFEEKFGVSAAAVAVAGPAGGGAAAAAEEKTEFTVVLAEAGANKVSVIKAVRELTGLGLKEAKDLVDGAPKPVKEGVDKAAAEEAKKKLEEAGAKVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: RCE1_YEAST
Sequence: MLQFSTFLVLLYISISYVLPLYATSQPEGSKRDNPRTIKSRMQKLTIMLISNLFLVPFLQSQLSSTTSHISFKDAFLGLGIIPGYYAALPNPWQFSQFVKDLTKCVAMLLTLYCGPVLDFVLYHLLNPKSSILEDFYHEFLNIWSFRNFIFAPITEEIFYTSMLLTTYLNLIPHSQLSYQQLFWQPSLFFGLAHAHHAYEQLQEGSMTTVSILLTTCFQILYTTLFGGLTKFVFVRTGGNLWCCIILHALCNIMGFPGPSRLNLHFTVVDKKAGRISKLVSIWNKCYFALLVLGLISLKDTLQTLVGTPGYRITL
What is the function of this protein?
Proteolytically removes the C-terminal three residues of farnesylated proteins, including the a-factor mating pheromone and RAS.
What are the official names of this protein?
CAAX prenyl protease 2, Prenyl protein-specific endoprotease 2, PPSEP 2, Ras and A-factor-converting enzyme, RACE.
What is the protein family that this protein belongs to?
Belongs to the peptidase U48 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: DTD_XANCP
Sequence: MLALIQRVTRASVAVDAQVVGQIGPGLLALIGIEPGDTAPQLRRLAERLLGYRVFSDEAGKMNRSLADTGGGLLLVSQFTLAADTKAGMRPSFSTAAPPEEAERAFNQLVAICREKHSGGVETGRFGAHMVVDLVNDGPVTFLLRP
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BETL_LISMN
Sequence: MKKLTNVFWGSGFLVLLAVLFGAFLPEQFETFTNHIQKFLTSNFGWYYLIVVAIIIIFCLFLVLSPIGSIRLGKPGEEPGYSNKSWFAMLFSAGMGIGLVFWGAAEPLSHYAVQAPGGEVGTQAAMKDALRYSFFHWGISAWSIYAIVALALAYFKFRKNAPGLISATLYPILGKHAKGPIGQLIDIIAVFATVIGVATTLGLGAQQINGGLTYLFGVPNNFTVQFTIIVIVTILFMLSAMSGLDKGIQLLSNVNIYVAGVLLVLTLILGPTLFIMNNFTNSFGDYLQNIIQMSFQTAPDAPDARKWIDSWTIFYWAWWLSWSPFVGIFIARISRGRTIRQFLLGVIVLPALVSVFWFAVFGGSAIFVEQHGNSGLSSLATEQVLFGVFNEFPGGMMLSIVAMILIAVFFITSADSATFVLGMQTTGGSLNPPNSVKVTWGLLQAGIASVLLYAGGLTALQNASIIAAFPFSIVIILMIVSLFVSLTREQEKLGLYVRPKKSQRSQL
What is the function of this protein?
High-affinity uptake of glycine betaine, driven by a sodium-motive force.  Involved, with GbuABC and OpuC, in osmoprotection and cryoprotection of Listeria.  Does not mediate either carnitine or choline uptake.
What are the official names of this protein?
Glycine betaine transporter BetL, Glycine betaine-Na(+) symporter.
What is the protein family that this protein belongs to?
Belongs to the BCCT transporter (TC 2.A.15) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYGB_ACAM1
Sequence: MATFLLEVGTEELPASFVESAIQQWRSHIPNSLEEHLLTPQSLKVYGTPRRLAILAEGLPDQQPDQTVEVKGPPAKAAFKDGKPTKAAEGFARKQGVEIKDFELRDTEKGEFIFVQKTTLGKPAVDVLADLIPTWIFSLEGKRFMRWSDGEVKFSRPIRWLVSLLDDHLIPIKLENSTGTISSDRTSSGHRVLHPDPVTIKHPQDYVATLEKASVQVDPEQRQTLIKEQVHACAKAVKGKAVISEDLLAEVTYLVEWPTAVVGGFESEFLELPAEVITTEMVSHQRYFPVEAPKGAKLLPHFITISNGDPAKSDIISSGNERVIRARLADGQFFYKADQAMPLAEYLPKLETVTFQEDLGSVRAKVDRIQANALWVAKQLQLDQKVTQQVERAAQLCKADLVTQMVGEFPELQGVMGEKYAIASGEPTEIATAIVEHYLPKGANDQLPQTLVGQIVGIADRLDTLVSIFGLGMIPTGSSDPFALRRAANAILNIVWAANLDLNLDQLLTETTAAFAQTFAKFQPEVQQLRDFFGQRLRSLLQDEQTIDYDLVNAVLGEKGEHTQRVLVDVLDGRDRAQYLQTIRTNGTLDTIYETVNRAARLATKGDLASDVLDPKGVVQPKLFEQSSEQVFYDGLLTLLPQTQAAQSSRDYQKLVQGLTKIAPSVSQFFDGDDSVLVIAEDADLRANRLNLLGLLRNHALVLGDFGAIVKS
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XYLA_ARATH
Sequence: MKKVEFFMLLLCFIAASSLVSADPPTCPADLGGKCSDSDDWQGDFFPEIPKIKYEGPSSKNPLAYRWYNAEEEILGKKMKDWFRFSVAFWHTFRGTGGDPFGAATKYWPWEDGTNSVSMAKRRMRANFEFLKKLGVDWWCFHDRDIAPDGTTLEESNKNLDEVIELAKELQKGSKIKPLWGTAQLFLHPRYMHGGATSSEVGVYAYAAAQVKKAMEVTHYLGGENYVFWGGREGYQTLLNTDMGRELDHLARFFEAAVAYKKKIGFKGTLLIEPKPQEPTKHQYDWDAATAANFLRKYGLIDEFKLNIECNHATLSGHTCHHELETARINGLLGNIDANTGDAQTGWDTDQFLTDVGEATMVMMSVIKNGGIAPGGFNFDAKLRRESTDVEDLFIAHISGMDTMARGLRNAVKILEEGSLSELVRKRYATWDSELGKQIEEGKADFEYLEKKAKEFGEPKVSSAKQELAEMIFQSAM
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
Protein: PDI_RICCO
Sequence: MASFRGSIWYCIFVLSLIAVAISAAESEEEQSSVLTLDSTNFTDTISKHDFIVVEFYAPWCGHCKKLRPEYEKAASILKSHDIPVVLAKVDANEEANKELATQYDIKGFPTLKILRNGGKSIQEYKGPREADGIAEYLKKQSGPASVEIKSTEAANTFIGDKKIFIVGVFPKFSGEEYENYMSVADKLRSDYEFGHTLDAKHLPQGESSVTGPVVRLFKPFDELFVDFKDFNVDALEKFVEESSMPVVTVFNSDPSNHPFVIKFFNSPDAKAMLFMNFNGEAADSIKSKYQEVAHQFKGEGIILLLGDVEASQGAFQYFGLKEDQVPLIIIQTNDGQKYLKANLEPDHIAPWVKAYKEGKVQAYRKSEPIPEVNNEPVKVVVADTLQDIVFNSGKNVLLEFYAPWCGHCKQLAPILDEVAVSYKSDADIVIAKLDATANDIPSDTFDVRGYPTVYFRSASGKVEQYDGDRTKDDIISFIEKNRDKAAQQESANGKDEL
What is the function of this protein?
Participates in the folding of proteins containing disulfide bonds, may be involved in glycosylation, prolyl hydroxylation and triglyceride transfer.
What are the official names of this protein?
Protein disulfide-isomerase, PDI.
What is the protein family that this protein belongs to?
Belongs to the protein disulfide isomerase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: ZRAP_SALPA
Sequence: MKRNNKSAIALIALSLLALSSGAAFAGHHWGNNDGMWQQGGSPLTTEQQATAQKIYDDYYTQTSALRQQLISKRYEYNALLTASSPDTAKINAVAKEMESLGQKLDEQRVKRDVAMAQAGIPRGAGMGYGGCGGYGGGYHRGGGHMGMGNW
What is the function of this protein?
Binds zinc.  Could be an important component of the zinc-balancing mechanism (By similarity).
What are the official names of this protein?
Zinc resistance-associated protein.
What is the protein family that this protein belongs to?
Belongs to the ZraP family.
What are the subcellular locations of this protein?
Periplasm.
Protein: CHI2_METAN
Sequence: MHHLRALVGVGLAGLAAGVPLTDKISVKPRQAPGAQNVVYWGQNGGGTIENNDLAAYCQPNSGIDVLVLAFLYQFGNGGNIPSGTIGQSCYISTSGQGQNCEALTAAIHTCQSAGVKIVLSLGGATSSYSLQTQAQAEQIGQYLWDSYGNSGNKTVQRPFGSNFVNGFDFDIEVNGGSSQYYQYMIAKLRANFASDKSNTYLITGAPQCPIPEPNMGVIISNSVFDHLYVQFYNNNNYTVPCALGINGNAPFNYNNWTSFIADTPSAGAKIFIGVPASPLASTGTPSGAQYYAAPEQLAAIVGEYRSDAHFGGIMMWSAGFSDANVNDGCTYAQQAKSILVNGAPCPSSGPPSSTPATAPAPTATTMPSSTSVSSPTASPTGGTVPQWGQCGGEGYSGPTQCVPPYQCVKQGDWWSSCR
What is the function of this protein?
Secreted chitinase involved in the degradation of chitin, a component of the cell walls of fungi and exoskeletal elements of some animals (including worms and arthropods).  Participates in the infection process and directly acts in the penetration process of the host cuticle.
What are the official names of this protein?
Endochitinase 2, Chitinase 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family. Chitinase class III subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PSD_ECOUT
Sequence: MLNSFKLSLQYILPKLWLTRLAGWGASKRAGWLTKLVIDLFVKYYKVDMKEAQKPDTASYRTFNEFFVRPLRDEVRPIDTDPNVLVMPADGVISQLGKIEEDKILQAKGHNYSLEALLAGNYLMADLFRNGTFVTTYLSPRDYHRVHMPCNGILREMIYVPGDLFSVNHLTAQNVPNLFARNERVICLFDTEFGPMAQILVGATIVGSIETVWAGTITPPREGIIKRWTWPAGENDDSVALLKGQEMGRFKLGSTVINLFAPGKVNLVEQLESLSVTKIGQPLAVSTETFVTPDAEPAPLPAEEIEAEHDASPLVDDKKDQV
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SYI_STAA2
Sequence: MDYKETLLMPKTDFPMRGGLPNKEPQIQEKWDAEDQYHKALEKNKGNETFILHDGPPYANGNLHMGHALNKILKDFIVRYKTMQGFYAPYVPGWDTHGLPIEQALTKKGVDRKKMSTAEFREKCKEFALEQIELQKKDFRRLGVRGDFNDPYITLKPEYEAAQIRIFGEMADKGLIYKGKKPVYWSPSSESSLAEAEIEYHDKRSASIYVAFDVKDDKGVVDADAKFIIWTTTPWTIPSNVAITVHPELKYGQYNVNGEKYIIAEALSDAVAEALDWDKASIKLEKEYTGKELEYVVAQHPFLDRESLVINGDHVTTDAGTGCVHTAPGHGEDDYIVGQKYELPVISPIDDKGVFTEEGGQFEGMFYDKANKAVTDLLTEKGALLKLDFITHSYPHDWRTKKPVIFRATPQWFASISKVRQDILDAIENTNFKVNWGKTRIYNMVRDRGEWVISRQRVWGVPLPVFYAENGEIIMTKETVNHVADLFAEHGSNIWFEREAKDLLPEGFTHPGSPNGTFTKETDIMDVWFDSGSSHRGVLETRPELSFPADMYLEGSDQYRGWFNSSITTSVATRGVSPYKFLLSHGFVMDGEGKKMSKSLGNVIVPDQVVKQKGADIARLWVSSTDYLADVRISDEILKQTSDVYRKIRNTLRFMLGNINDFNPDTDSIPESELLEVDRYLLNRLREFTASTINNYENFDYLNIYQEVQNFINVELSNFYLDYGKDILYIEQRDSHIRRSMQTVLYQILVDMTKLLAPILVHTAEEVWSHTPHVKEESVHLADMPKVVEVDQALLDKWRTFMNLRDDVNRALETARNEKVIGKSLEAKVTIASNDKFNASEFLTSFDALHQLFIVSQVKVVDKLDDQATAYEHGDIVIEHADGEKCERCWNYSEDLGAVDELTHLCPRCQQVVKSLV
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHNN_ENTLS
Sequence: MTGKLIWLVGPSGSGKDSLLEALRKQEHPQMLVAHRYITRPAGAGCENHVALSEHEFFTRAAQHLFALSWHANNLYYGVGMEIDLWLHAGLDVVVNGSRAHLPQAKARYGESLLPVCLQVSPDILRQRLEQRGRENALEIAQRLERAARYTPQQCVMLNNDGSLLQSVEMFLHLIRTHGNHKESQHACL
What is the function of this protein?
Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).
What are the official names of this protein?
Ribose 1,5-bisphosphate phosphokinase PhnN, Ribose 1,5-bisphosphokinase.
What is the protein family that this protein belongs to?
Belongs to the ribose 1,5-bisphosphokinase family.
Protein: WDR48_DROGR
Sequence: MLTHKTCQARKKMQVSFVIRDAEEKQHRNGVNALQLDPNNGKLYSAGRDAIIRVWNTRTESNEKYIQSMEHHNDWVNDIVLCCNGRNLISASCDTTVKVWNAHKGFCMSTLRTHRDYVQALAYAKDREQVASAGLDKAIFLWDVNTLTALTASNNTVTTSSLTGSKDSIYSLAMNPSGTVIVSGSTENILRIWDPRTCMRSMKLRGHTENVRCLVVSPDGNQVVSGSSDGTIKVWNLGQQRCIQTIHVHKEGVWSLLMSENFQYIISGSRDRNIIVTEIRNPSNKMLVCEEKAPVLSLGYNIDKTGVWATTWNSDIRCWKLPMYDRCILTSGGMDAQWTLGGTEMACIRGGAAIKECTVLNDKRYIITKDSQDKVVVYDVLRVIKKEELGPIEYEKEVMKRNKQVYIPNWFTVDLKTGMPTIVLGQEEVDCFSAWVSIEAGLPECDDPTTEIKINYGKLLLEALLEYWTPPHSIPPNEMEPDVRGNGYFQVPKHTPVIFSEVGGRTVCRLLVRDAAGDSESTLLHETAPQWVTDVVIERNIPKFLKIPFFLQPHPQMTKPERSKKDRLVANEFIQCRKVCEHVLEKVLNTETTPSGGNANNSLQNSQSDANSEGSQLPAEERIELWCNDVVVDPNMDLRTVRHFIWKQSTDLTFQYKAKQNFNFDGK
What is the function of this protein?
Regulator of deubiquitinating complexes.  Activates deubiquitination by increasing the catalytic turnover without increasing the affinity of deubiquitinating enzymes for the substrate (By similarity).
What are the official names of this protein?
WD repeat-containing protein 48 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR48 family.
Protein: GPX5_ARATH
Sequence: MGASSSSSVSEKSIHQFTVKDSSGKEVDLSVYQGKVLLVVNVASKCGFTESNYTQLTELYRKYKDQGFVVLAFPCNQFLSQEPGTSEEAHQFACTRFKAEYPVFQKVRVNGQNAAPVYKFLKSKKPSFLGSRIKWNFTKFLVGKDGQVIDRYGTTVSPLSIQKDIEKALAQEL
What is the function of this protein?
May constitute a glutathione peroxidase-like protective system against oxidative stresses.
What are the official names of this protein?
Probable glutathione peroxidase 5.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: ARGB_RHOPB
Sequence: MTDAPEISPLDQARILSEALPHMQEYDEETIVIKYGGHAMGAEDLAKAFARDIVLLEQTAINPVVVHGGGPQIATMLKRLGIKSEFAAGLRITDAATIEIVEMVLAGSINKQLVGYINEAGGKAVGLCGKDGNMVSATKATRTMVDPDSRIEEVIDLGFVGEPEKVDLTLLNQLIGHELIPVLAPLATSSSGQTFNVNADTFAGAVAGALKAKRLLLLTDVPGVLDKSKKLIPELSVKDARRLIADGTISGGMIPKVETCIYALEQGVQGVVIIDGKTPHAVLLELFTNQGTGTLIHK
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS2_BACLD
Sequence: MQQKALSALEFHKVKEQLTEHAASSLGKEMLLELKPSRSLEEVKKLQEEVDEAGTVLRLKGSAPFGGLTDIRKALRRAEIGSILSPAELTEISGLLYAAKQMKHFLEGLFEDGVEIPYLHQYAEKLIPLSELERDINSCIDDHGEVLDHASETLRGIRTQLRTLESRIRDRLESMLRSSSAQKMLSDTIITIRNDRFVIPVKQEYRSSYGGIVHDQSSSGATLFIEPQAIVDMNNALRQAKVNEKQEIERILRVLTEKTAEHTNELFHDVKVLQTLDFIFAKAKYAKATKAVKPAVNADGYVRLIQARHPLLPLDEVVPNDIELGGEYTTIVITGPNTGGKTVTLKTLGLLTMMAQSGLHVPAEEGSETAVFDQVFADIGDEQSIEQSLSTFSSHMVNIVDILKDMTENSLVLFDELGAGTDPQEGAALAISILDEVCQTGARVIATTHYPELKAYGYNRENVINASVEFDIDTLSPTYKLLIGVPGRSNAFEISKRLGLPDYLIGRAKAEMTAEHNEVDTMIASLEDSKKRAEAELKETEAIRAEAEALHRDLQQQISEWQEKKDKLYEEAEQKAAEKVKAAMKEADDIIQSLRMIKEDHKAFKDHELIEAKKRLEEAVPSFEKAKKPAQKKTDKRELKPGDEVKVLTFGQKGTLLEKTGAAEWNVQIGILKMKVKEKDLEFLKSAPEPEKQKTIAAVKGKDYHVSLELDLRGERFENALHRVEKYLDDAVLAGYPRVSIIHGKGTGALRKGVQDLLKSHRNVKNSRFGEAGEGGSGVTIVELK
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: FPG_NITEC
Sequence: MPELPEVEVTRRGIDAHLAGRYITQVKIRNYALRWPVSPELITLLPGQRINTITRRAKYLLFACSKGTLIIHLGMSGSLRVLPVSTPSLLHDHFELWLDNEKMLRFRDPRRFGVILWWDGDVRQHPLLQKLGPEPLSDAFNGLFLHEKIQRRSISIKEALMNQHIVVGIGNIYANEALFHAGISPLIAAGSLSTALCARLVDAVKMTLQRAIEAGGSSLRDFTDCDGSPGCFQQQYWVYGRTGQPCRKCGALVSKTRQGQRSSFFCAQCQK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: LEUC_CERS4
Sequence: MTAPRTLYDKIWDDHVVHQSEDGTCLLYIDRHLVHEVTSPQAFEGLRMTGRKVRAPEKTIAVPDHNVPTTEGRDTKIDNEESRIQVEALDKNARDFGINYYPVSDIRQGIVHIVGPEQGWTLPGMTVVCGDSHTATHGAFGALAHGIGTSEVEHVLATQTLIQKKSKNMKVEITGSLRPGVTAKDITLSVIGLTGTAGGTGYVIEYCGQAIRELSMEGRMTVCNMAIEGGARAGLIAPDEKTFAYVMGRPHAPKGAAWEAALAYWKTLFTDEGAQFDKVVTIRGEDIAPVVTWGTSPEDVLPITATVPAPEDFTGGKVEAARRSLEYMGLTPGQKLTDIKIDTVFIGSCTNGRIEDLRAAAEILKGKKVAPGMRAMVVPGSGLVRAQAEEEGLAQIFIDAGFEWRLAGCSMCLAMNPDQLSPGERCASTSNRNFEGRQGRNGRTHLVSPGMAAAAAITGHLTDVRDLMMAPAEPA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: DUT_HHV6G
Sequence: MYSAISEKISETITLQRQTSSRYIEFFVFRNVDINELWTTDISEDKTHDVWPAVNKKSFKKFLENELTSYQRPIPLLGIPQNGTVSKTCKKEKQRETDCVNYERKHGNPVTFYPRHRAKRNANTDTCISEEPSILVSHHRNSKMDVFMDTNKITLVNRELIWVPHDQVRIVKLDISLYIPDGFFGVITGHSNDVFCECVTEIITDETDISVFLMNLSEHSLMLLPGDVEFSINFLPCYIPEPWEMINLSPPEFAIFHLKASREFIAKPNSYTIQYFDAMYVCADELKALMIPSKEIAKLGLLIETYIWNKDTIPSIKIFNSTRKTIYIPTGICIARIIFTCGHFCLSLMPERAINRLQVLDANSSFLFHYATSNNA
What is the function of this protein?
Involved in nucleotide metabolism: produces dUMP, the immediate precursor of thymidine nucleotides and decreases the intracellular concentration of dUTP to avoid uracil incorporation into viral DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: FABH_CHLTA
Sequence: MRASIWGTGSYLPKKILTNADLEKIVETSDEWISTRTGIKERRIASAEEFSSFMGAKAAEKAIEAAKISKSQVDCIVFSTAAPDYIFPSSAALAQAYLGIKEIPAFDCLAACTGFLYGLSIAKAYVESGMYQCVLVIAADKLSSFVNYQDRNTCVLFGDGGSACIVGHSRPGALEISKVNLGADGKQGDLLRLPAGGSRCPASQDTVQNHQHFITMEGKEVFKHAVRRMEFAAKTCITEAGLQEKDIDWLVPHQANERIIDAIAKRFAVKDSRVFKTLAKYGNTAASSVGIALDELLRTHDIHVAERLLLVAFGGGLSWGAVILQQV
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.