PharMolix/UniProtQA huggingface dataset:
Protein: NCAP_I46A1
Sequence: MASQGTKRSYEQMETGGERQNTTEIRASVGRMIGGIGRFYIQMCTELKLSDYEGRLIQNSITIERMVLSAFDERRNKYLEEHPSAGKDPKRTGGPIYRRIDGKWIRELILYDKEEISRIWRQANNGEDATAGLTHMMIWHSNLNDATYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTMVMELIRMIKRGINDRNFWRGENGRRTRIAYERMCNILKGKFQTAAQKAMMDQVRESRNPGNAEIEDLIFLARSALILRGSVAHKSCLPACVYGLAVASGHDFEREGYSLVGIDPFRLLQNSQVFSLIRPNENPAHKSQLVWMACHSAAFEDLRVSSFIRGKRVVPRGQLSTRGVQIASNENMETMDSSTLELRSRYWAIRTRSGGNTNQQRASAGQISVQPTFSVQRNLPFERATVMAAFTGNTEGRTSDMRTEIIRIMESARPEDVSFQGRGVFELSDEKATSPIVPSFDMSNEGSYFFGDNAEEYDN
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: TXL2A_SCOMO
Sequence: MFFLGFIIVCASEEQSDNRLPNIDFGLDRGHSGRMTAEYLMGLAAANDPNGPGRRRRSPIVREEILRHP
What are the official names of this protein?
U-scoloptoxin(21)-Sm2a, U-SLPTX(21)-Sm2a.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-21 family.
What are the subcellular locations of this protein?
Secreted.
Protein: BLAI_STAES
Sequence: MANKQVEISMAEWDVMNIIWGKKSVSANEIVVEIQKYKEVSDKTIRTLITRLYKKEIIKRYKSENIYFYSSNIKEDDIKMKTAKTFLNKLYGGDMKSLVLNFAKNEELNNKEIEELRDILNDISKK
What is the function of this protein?
Transcriptional repressor that constitutively blocks expression of beta-lactamase.  Binds DNA as a dimer (By similarity).
What are the official names of this protein?
Penicillinase repressor, Beta-lactamase repressor protein, Regulatory protein BlaI.
What is the protein family that this protein belongs to?
Belongs to the BlaI transcriptional regulatory family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CADB_ECO57
Sequence: MSSAKKIGLFACTGVVAGNMMGSGIALLPANLASIGGIAIWGWIISIIGAMSLAYVYARLATKNPQQGGPIAYAGEISPAFGFQTGVLYYHANWIGNLAIGITAVSYLSTFFPVLNDPVPAGIACIAIVWVFTFVNMLGGTWVSRLTTIGLVLVLIPVVMTAIVGWHWFDAATYAANWNTADTTDGHAIIKSILLCLWAFVGVESAAVSTGMVKNPKRTVPLATMLGTGLAGIVYIAATQVLSGMYPSSVMAASGAPFAISASTILGNWAAPLVSAFTAFACLTSLGSWMMLVGQAGVRAANDGNFPKVYGEVDSNGIPKKGLLLAAVKMTALMILITLMNSAGGKASDLFGELTGIAVLLTMLPYFYSCVDLIRFEGVNIRNFVSLICSVLGCVFCFIALMGASSFELAGTFIVSLIILMFYARKMHERQSHSMDNHTASNAH
What is the function of this protein?
Under acidic conditions, in the presence of lysine, functions as a cadaverine:lysine antiporter that facilitates the excretion of cadaverine and the uptake of lysine.
What are the official names of this protein?
Cadaverine/lysine antiporter.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: XYLA_CALBD
Sequence: MKYFKDIPEVKYEGPQSDNPFAFKYYNPDEIIDGKPLKDHLRFAIAYWHTFCATGSDPFGQPTIVRPWDKFSNRMDNAKARVEAAFEFFELLDVPFFCFHDRDIAPEGENLKESNKNLDEIVSLIKEYLKTSKTKVLWGTANLFSHPRYVHGAATSCNADVFAYAAAQVKKALEVTKELGGENYVFWGGREGYETLLNTDMGLELDNLARFLHMAVEYAKEIGFDGQFLIEPKPKEPTKHQYDFDSAHVYGFLKKYDLDKYFKLNIEVNHATLAGHDFHHELRFARINNMLGSIDANMGDLLLGWDTDQFPTDVRLTTLAMYEVIKAGGFDKGGLNFDAKVRRGSFELEDLVIGHIAGMDAFAKGFKIAYKLVKDGVFDKFIDERYKSYKEGIGAKIVSGEANFKMLEEYALSLDKIENKSGKQELLEMILNKYMFSE
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUKB_PECAS
Sequence: MIERGKFRSLTLVNWNGFFARTFDLDELVTTLSGGNGAGKSTTMAAFITALIPDLTLLHFRNTTEAGATSGSRDKGLHGKLRAGVCYSTLDVVNSRHQRVLVGVRLQQVAGRDRKVDIKPFTIQGLPTAIQPTQILTQIVGDRQARVLSLQELKERVEEMEGVQFKQFNSITDYHSLMFDLGVVPRRLRSASDRSKFYRLIEASLYGGISSAITRSLRDYLLPENSGVRKAFQDMEAALRENRMTLEAIRVTQSDRDLFKHLISEATSYVAADYMRHANERRIHLDGALELRRDLFSSRKQLSSEQYRHVEMARELTEQNDTEGDLETDYQAASDHLNLVQTAMRQQEKIERYNADLEELSYRLEEQNEVVEEARDQQAENEERADAAELEVDELKSQLADYQQALDVQQTRAIQYQQAQQALERARTLCQLPDLTAENADEWLDSYQAREQEATEILLMLEQKLSVADAAHGQFEQAYQLVSKIAGAVSRSEAWQVARDLLRDSSSQRYQAERVQPLRMRLSELEQRLREQQDAERLLQDFSKRNGQDYQPEELESLQQELDARIETLSSLVAEAGERRMTLRQELEQTQQRIQKLTARAPVWLAAQETLTQLSEQSGETFEDSRQVTEFMQQLLERERETTVERDDIAARKRQIEAQVDRLSQPGGSEDPRLNALAERFGGVLLSEIYDDVTLDDAPYFSALYGPSRHAIVVSDLSLIRDQLAGLEDCPEDLYLIEGDPQSFDDSVFAVDELERAVVVKVAERQWRYSRFPEVPLFGRAAREMRLEGLRDEREALAEQYATLSFDVQKTQRLHQSFSRFIGTHLAVVFDEDPEAEIRTLSSRRGELDRAMASFDGENQQQRQQYEQAKEASGQLNKLIPRISLLCDETLQDRVEEIRAELDETEESARFIQQHGVTLTKLEPLVSVLQSDPQQHEQLQEDYTQAQNAQRQAKQQAFTLTEVVQRRAHFSYADSAGMLGENAGLNDKLRHRLEQAEAERTKAREQLRQHQTQLTQYSQVQASLKSSYDAKQDMLKELLQELQDIGVRADADAEARARQRRDELHAALSTNRSRRNQLEKQITFCEAEMDSVQKKLRKLERDYHQMREQVVTAKAGWCTVMRLVKDNGVERRLHRRELAYMEGDELRSMSDKALGALRLAVADNEHLRDVLRLSEDPKRPERKIQFYIAVYQHLRERIRQDIIRTDDPVEAIEQMEIELNRLTEELMAREQMLAISSRSVANIIRKTIQREQNRIRMLNQGLQAVSFGQVKSVRLNVNVRETHTTLLNVLSEQQEMHQDLFNSNRLTFSEALAKLYQRLNPEIDMGQRTPQTIGEELLDYRNYLEMEVEVNRGADGWLRAESGALSTGEAIGTGMSILVMVVQSWEEESKRLRGKDIIPCRLLFLDEAARLDAKSIATLFELCDRLEMQLVIAAPENISPEKGTTYKLVRKVYQNNEHVHVVGLRGFGTETPETQEPAS
What is the function of this protein?
Plays a central role in chromosome condensation, segregation and cell cycle progression.  Functions as a homodimer, which is essential for chromosome partition.  Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes.  May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
What are the official names of this protein?
Chromosome partition protein MukB, Structural maintenance of chromosome-related protein.
What is the protein family that this protein belongs to?
Belongs to the SMC family. MukB subfamily.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: RF3_HAES1
Sequence: MSYSQQVNKRRTFAIISHPDAGKTTITEKVLLYGNAIQKAGSVKGKGSQAHAKSDWMEMEKQRGISITTSVMQFPYHDCLVNLLDTPGHEDFSEDTYRTLTAVDSCLMVIDSAKGVEERTIKLMEVTRLRDTPILTFMNKLDRDIRDPMELLDEVESVLKIRCAPITWPIGCGKLFKGVYHLYKDETYLYQSGQGHTIQDVRIIKGLNNVDLDRAVGEDLARQLRDELELVKGASNEFDHDLFIRGELTPVFFGTALGNFGVDHFLDGLTQWAPAPQARQADCRLVESAEEKLTGFVFKIQANMDPKHRDRVAFMRIVSGKYEKGMKLKQVRLGKEVVLSDALTFMAGDRSHAEEAYAGDIIGLHNHGTIQIGDTFTQGEDLKFTGIPNFAPELFRRIRLKDPLKQKQLLKGLVQLSEEGAVQVFRPLTNNDLIVGAVGVLQFDVVVSRLKSEYNVEAVYETVNVAAARWVECSEAKKLEEFKRKNEQNLALDGGDSLTYIAPTMVNLNLTQERYPDIQFFKTREH
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBE8_SCHPO
Sequence: MTDLRRNRYSISAGVGKSVLDSLGKFYGSPKRQLPNKFEAGKEYTGYNAPWIPFALDWLKQGKYSSEWIAMGSLNEEPNNMIQLLKLITGDDGNSHLEKAQAATDLEYPVTKLLWNPSSVGSNTDSQLLASTDQQLRLWKTDFEAGIDSPLLCQASLSTHVKTHNNAPLTSFDWCKTDPSYIVVSSLDTTCTVWDIVAQQSKTQLIAHDKEVYDVAFLKDSINVFVSVGADGSVRMFDLRSLDHSTIIYEGDSTFWKRNGDYTNASPPVSAPLLRLSACDSDVNLMATFHHNSSDVQMIDIRVPGTAYATLRGHKGDVNAVKWMPGSKSKLATCGDDCVVSLWDLDQPVNPSPAPTLSVSGTTPGMTGSTSEYVTPVSSVNSMRETASPLNADNQYSPLLSWKLEHEVNNLSWSVKNDGLAVVYGKSLEILKVPQ
What are the official names of this protein?
Uncharacterized WD repeat-containing protein C17D11.08.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus.
Protein: T2R38_HYLKL
Sequence: MLTLTRICTVSYEVRSTFLFISVLEFAVGFLTNAFIFLVNFWDVVKRQPLSNSDCVLLCLSISRLFLHGLLFLSAIQLTHFQKLSEPLNHSYHAIIMLWMIANQANLWLATCLSLLYCSKLIRSSHTFLICLASWVSRKICQMLLGIILCSCICTVLCVWCYFSRPHFTVTTVLFTNNNTRLNWQIKDLNLFYSFLFCYLWSVPPFLLFLVSSGMLTVSLGRHMRTMKVYTRDFRDPSLEAHIKALKSLVSFFCFFVISSCAAFISVPLLILWRDKIGVMVCVGIMAACPSGHAAILISGNAKLRRAVTTILLWAQSSLKVRADHKADSRTLC
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 38, T2R38.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FSHR_NOTEU
Sequence: MAFLWISFLVFLGSGSGCHHRICHCSDRVFICQESKVTEIPSDIPRNTVEMRFVLTKLQVIPRGAFSGFRDLEKIEISQNDALEVIEADVFSNLPKLHEIRIEKANNLVLIDPEAFWNLPNLRYLLISNTGIKHLPAVYKIQSHQKVLLDIQDNINIRTIERNSFAGLSSESEILWLNKNGIQEIQNQAFNGTQLDELNLSDNINLEDLPNGIFQGANGPVILDISRTRIHSLPSDGLKNLKKLKARSAYNFKTLPNLDKFAELVEANLTYPSHCCAFANWRRQAFELHPICNKSFVRQDSDDLAMDWGHRRRSVEEEYVSNLDKGFDITDTELDYDLCNEVVDVACSPKPDAFNPCEDIMGYNFLRVLIWFISILSITGNIVVLVILITSQYKLTVPRFLMCNLAFADLCIGIYLLLIASVDIHTKSQYHNYAIDWQTGAGCDAAGFFTVFASELSVYTLTAITLERWHTITYAMQLDRKVRLRHAASIMLIGWIFAFSVALLPIFGVSSYMKVSICLPMDIDSPLSQFYVISLLVLNVLASVIICTCYTHIYFTVRNPNIISSTSDAKIAKRMAMLIFTDFLCMAPISFFAISASVKMPLITVSKSKILLVLFYPINSCANPFLYAVFTKTFRRDFFILLSKFGCCEMQAQIYRTETSSTVHSSHPRNGQCPLMAKSNSGAVYKLVPLNHLS
What is the function of this protein?
G protein-coupled receptor for follitropin, the follicle-stimulating hormone.  Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.
What are the official names of this protein?
Follicle-stimulating hormone receptor, FSH-R, Follitropin receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ENO_BDEBA
Sequence: MSEIISVISREILDSRGNPTVEVEVTTADGNMGRAAVPSGASTGAHEACELRDGDKNRFLGKGVYKAVDNVREKIAPEIVGLQATEQVYIDKILRDIDGTENKSNLGANAILGVSLAVAKAAAKDCRLPLYRYVGGSQASRLPVPLMNVLNGGAHANNGLDIQEFMIVPTVNNSYAESLRAGTEIFHTLKKILAKKGLSTAVGDEGGFAPKLGSNQEALDLLMNAIVDAGYDPGQNVFLALDVAATEMFKEGKYEWQGGHISPTELLGIYKSWAEKYPLVSIEDGFAEDDWDSWVQSTAQMGSTMQLIGDDLFVTNPKRLRMGLEKKAGNALLVKVNQIGTLTETYEAVNLAQRNKFRTIMSHRSGETEDVTIADLAVGLNCHQIKTGSLCRGERTAKYNQLLRIEEDLGGMGLYWDKAAFR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: HKM9_ASPHA
Sequence: MPATTRLITIYGATGNQGGGVARSLLKNPCFQVRALTRNPNSPASQELAGLGAEIRRADGFDSNSLLAAFEGSWGVFVNINSDDKAFRPAGPTEYDLGMKIVDMAAQAGVQHFVFSSGPSSTELTNGKIRMKAMEMKNKIERYARNNTQFQTVSFICAAWYLENFLVKEIAPLFGGFPFVADAEAFLTFRCPRWGGKEDVPFISISDDYGDIVQGLFLDPHRWNGHVVHGCSDILTFDELVTHFQNVTGQKARFQPLESWETFDTFGVPELEDTKLMFGLTQTTGGLYFGPEPSEKNTAAALKRATAAALGLPRDQQTLITVKGWFQKHFPVTPN
What is the function of this protein?
NmrA-like family domain-containing oxidoreductase; part of the gene cluster that mediates the biosynthesis of hancockiamides, an unusual new family of N-cinnamoylated piperazines (PubMed:33242032).  The NRPS hkm10 and the NmrA-like reductase hkm9 are proposed to convert two molecules of L-Phe to the intermediary piperazine called xenocockiamide A (Probable).  Xenocockiamide A is then converted to hancockiamide D via a series of hydroxylations and O-methylations (Probable).  The tyrosinase hkm6 may catalyze an aromatic hydroxylation, then the 2-oxoglutarate-dependent Fe(II) dioxygenase hkm4 and the FAD-dependent phenol hydroxylase hkm7 may catalyze consecutive hydroxylations to install 2 more hydroxy groups, and the methyltransferase hkm8 probably catalyzes two methylations using 2 molecules of S-adenosyl-L-methionine (SAM) (Probable).  The NRPS hkm11 activates and transfers trans-cinnamate supplied by the PAL hkm12 to hancockiamide D and produces hancockiamide A (PubMed:33242032).  NRPS Hkm11 has the flexibility to tolerate the bulky hancockiamide G as a substrate and the absence of the acetyl-transferase hkm3 opens up the opportunity for hkm11 to introduce a second N-cinnamoyl moiety (PubMed:33242032).  The cytochrome P450 monooxygenase hkm5 catalyzes the methylenedioxy bridge formation, converting hancockiamide A into hancockiamide G (PubMed:33242032).  Hkm5 can also convert hancockiamide B into hancockiamide C, and hancockiamide D into hancockiamide H (PubMed:33242032).  The N-acetyltransferase hkm3 finally transfers an acetyl group to 1-N of piperazine, converting hancockiamide A into hancockiamide B and hancockiamide G into hancockiamide C (PubMed:33242032).
What are the official names of this protein?
NmrA-like family domain-containing oxidoreductase hkm9, Hancockiamides biosynthesis cluster protein 9.
What is the protein family that this protein belongs to?
Belongs to the NmrA-type oxidoreductase family.
Protein: SSRP_STRM5
Sequence: MSKNSVKDKAKSATANKTIALNKRARHEYHIEERFEAGLALQGWEVKSIRAGRGNIIDAYAYVKQGEIFLIGAQITPLIQASTHVVANDRRERKLLLHRSEIDKLVGKVERDGYTIVPTAMYWSKNKIKLEVALAKGKQTHDKRDAAKDRDWAIEKQRVMRRGNRDA
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: FBL84_ARATH
Sequence: MGSRDFISSLPDEVLGKKILSLLPTKLVVSTSVLSKRWRNLFHFVDSFDLEDSTPIRNADSFSDFMKDTVALLSNCPIKRLTLNSHYEKSSVNRWIRSALKRGCLELNLQSQYDHYLDIGIFFRNNTLVKLTLSSYRTFLRGNVPPEGRVFFPALKTLSLGAVVAKPALYNWLISGCPVLEELFILDVGSGDDQPTWTRSVVSASIKRLTIVFHFPHNTYPYEDDVEIKTPNLEFLDYSALRSDGSDVDYLDSLAEARLDLRLWELTNTFDFGEVTNLVSAIRNVKTLHLSSSSLEAFYYRCYTMPVFDKLIHLSIESDKENGWQALPRLLLKSPNLQTLAIKGLLHKVTYRCGNACACTSKPKKRYLYKRYEDDSPTSEVEGRCCLSTCRVKVLEISGYGGSLREVKQMEHFLRKLKYLETVKIGVEEDNDSEHLRTELMTLDIASSKCNIQFI
What are the official names of this protein?
F-box/LRR-repeat protein At5g35995.
Protein: SSRP_PETMO
Sequence: MTTLARNKKATHDYEIIETFEAGISLLGTEVKSSKAGKINFKDSFCKIEKGELILYNVHISPYSGASIFNHDPERPRKLLLHKKEIRRLQSKVQQEGLTMIPLEIYTNNKGLIKVKIALAKGLKKYDKREKIAEKEYERRIRKQQKYENI
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: AROE_HELPG
Sequence: MKLKSFGVFGNPIKHSKSPLIHNACFLTFQKELGFLGHYHPILLPLESRIKNEFLHLGLSGANVTLPFKERAFQICDKIKGIALECGAVNTLVLEDDELVGYNTDALGFWLSLGGEDYQSALILGSGGSAKALACELKKQGLKVSVLNRSSRGLDFFQRLGCDCFMDPPKSAFDLIINATSASLNHELPLNKEVLKGYFKEGQLAYDLAYGFLTPFLSLAKELETPFQDGKGMLIYQASLSFEKFSASQIPYPKVFEVMRSVF
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: TRMD_STRS7
Sequence: MKIDILTLFPEMFAPLEHSIVGKAKEKGLLDIHYHNFRDHAEKARHVDDEPYGGGQGMLLRAQPIFDTMDSIQATKPRVILLDPAGKPFHQSYAEELALEEELIFICGHYEGYDERIKTLVTDEISLGDFVLTGGELAAMTMIDATVRLIPNVLGKQASHQEDSFSSGLLEYPQYTRPYDYRGMKVPDVLMSGHHEHIRLWRMEQSLKKTYLRRPDLLETYDFSDEERRIFDSIKSELSEGEN
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_UREPA
Sequence: MTNKVIQRNIHISHRKASLVIDLVRNKPVHEAIRILSNTPKKFAPIVLKLLNSAISNVQHNSKDMDPSKLYIYKIVANQGPTMKRTLPRAKGSADQLFKRTTHLEIVLSDDVNEREKELAAIKAKKSKKPLAVEPIAKVETKKVAKPSKVEIKPVEKDENVDPELLKREQQVLKVVEKTASQKEEETTETIMISTSPKNAQVLFDDLEKNVIFYKTTPINKVLRVLVYVTSPTKKVVGEFDLESVEIGAISSIWRKYSKQSVISKKEYDAYYEGKDKAHALVSKKAYKYRNPKDLSEYNMTKGPSGFQYLK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RSMI_HAEIN
Sequence: MTDLTGILYIVATPIGNLQDITQRALETFAQVDLIAAEDTRHSGLLLSHYGIKKPFFALHDHNEQEKAHILVEKLKQGSNIALISDAGTPLISDPGFHLVRQCREAGIRVVPLPGACAAITALCASGIASDRFCFEGFLPAKSKARKDKLENIAEEDRTLIFYESTHRILDTLEDMQAVLGEERYIVLAREMTKTWETITGNTIKNLREWLLEDPNRTKGEMVLIVEGKPKSDNNDEISPQAVKALELIAEELPLKKAAAIVAELYGYKKNALYQFGLAHLEK
What is the function of this protein?
Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase I, 16S rRNA 2'-O-ribose C1402 methyltransferase, rRNA (cytidine-2'-O-)-methyltransferase RsmI.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TY14_PITCE
Sequence: FPPWVL
What are the official names of this protein?
Tryptophyllin-14.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Tryptophillin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CH601_CORGB
Sequence: MAKLIAFDQDAREGILRGVDALANAVKVTLGPRGRNVVLDKAFGGPLVTNDGVTIARDIDLEDPFENLGAQLVKSVAVKTNDIAGDGTTTATLLAQALIAEGLRNVAAGANPMELNKGIAAAAEKTLEELKARATEVSDTKEIANVATVSSRDEVVGEIVAAAMEKVGKDGVVTVEESQSIETALEVTEGISFDKGYLSPYFINDNDTQQAVLDNPAVLLVRNKISSLPDFLPLLEKVVESNRPLLIIAEDVEGEPLQTLVVNSIRKTIKVVAVKSPYFGDRRKAFMDDLAIVTKATVVDPEVGINLNEAGEEVFGTARRITVSKDETVIVDGAGSAEEVEARRAQIRREIANTDSTWDREKAEERLAKLSGGIAVIRVGAATETEVNDRKLRVEDAINAARAAAQEGVIAGGGSALVQIAETLKAYAEEFEGDQKVGVRALATALGKPAYWIASNAGLDGSVVVARTAALPNGEGFNAATLEYGNLINDGVIDPVKVTHSAVVNATSVARMVLTTEASVVEKPAEEAADAHAGHHHH
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 1, 60 kDa chaperonin 1, Chaperonin-60 1, Cpn60 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EUTC_LACP7
Sequence: MDEQSLRKMVEQMVEQMVGGGTNVKSTTSTSSVGQGSATAISSECLPDITKIDIKSWFLLDHAKNKEEYLHMKSKTPARLGVGRAGARYKTMTMLRVRADHAAAQDAVFSDVSEEFIKKNKFVFVKTLCKDKDEYLTRPDLGRRFGKEELEVIKKTCGQSPKVLIIVGDGLSSSAIEANVEDMIPAIKQGLSMFQINVPPILFIKYARVGAMDDIGQATDADVICMLVGERPGLVTAESMSAYICYKAKHGVPESKRTVISNIHRGGTTPVEAGAHAAELIKKMLDKKASGIELKG
What is the function of this protein?
Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds.  Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
What are the official names of this protein?
Ethanolamine ammonia-lyase small subunit, EAL small subunit.
What is the protein family that this protein belongs to?
Belongs to the EutC family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: GGGPS_HALWD
Sequence: MNGPWTEWDHVLKVDPDKPLVDGETFEDVCQTGTDAIEIGGTLDITTEKMQEVVDACSRYDMPLYQEPSNPAVVVESDALDGYLVPTVFNAESAFWVAGAHKEWVRIDGPLDWERTATEAYIVLNPDASVAEVTEANTDQTAEDVAAFATVAERLFGQEIIYIEYSGTFGDTKKVAAAAAALTESTLFYGGGIGGYDSAYEMGAHADTIVVGDLLHDEGVDAVSETVAGVKDAHADGEI
What is the function of this protein?
Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).  This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
Geranylgeranylglyceryl phosphate synthase, GGGP synthase, GGGPS, (S)-3-O-geranylgeranylglyceryl phosphate synthase, Phosphoglycerol geranylgeranyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GGGP/HepGP synthase family. Group I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.