PharMolix/UniProtQA huggingface dataset:
Protein: PGK_MYCA9
Sequence: MAIKSLNDLLAEGVSGKGVLVRSDLNVPLEYLDGNIAHISDPGRIVASVPTIRALAGAGAKVIVTAHLGRPDGKPDPKLSLAPVGAALGELLGQHVQVAGDVVGTDALARAEGLTDGDVLLLENIRFDPRETSKDDAQRLALARELAELVGGPTGTGGAFVSDGFGVVHRKQASVYDVATLLPHYAGGLVAAEVEVLRVLTASTERPYAVVLGGSKVSDKLAVIESLATKADSLVIGGGMCFTFLAAQGLPVGKSLVQLEMVDTCKRLLDTYADVIHLPMDIVAADEFAADSPSEIVAADAIPDSKMGLDIGPESVKRFAAVLSNAKTIFWNGPMGVFEFPAFAAGTRGVAEAIIAATEKGAFSVVGGGDSAAAVRALDLPDDGFSHISTGGGASLEYLEGKVLPGIDVLED
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELO_CLOBA
Sequence: MKNKEIIINNYLNLENNYIKLPKKLFSEQNPSEVPSTNLVVFNESLASDLGLSEEFLQSDDGINFLSGNKILEDTIPIAQAYAGHQFGHFTMLGDGRAILLGELKSQNGERFDIQLKGSGRTPYSRGGDGKATLGAMLREYIISEGMHGLGIPTTRSLAVVSTGEDVIREEILKGAVLTRIAKSHIRVGTFQFISNYGTIEELKALADYTLNRHLKKAEYEGNPYIYLLNEVIKSQAKLISKWQLVGFVHGVMNTDNVTISGETIDYGPCAFMDVYDPDTVFSSIDINGRYAYGNQPKIGVWNLARFAETLLPLLDEDLESAVEIAQNSISKYSDLYNKYWYTGMRAKLGIFNEKEEDKELIQSLLTMMKRFKADYTNTFSNLTLGNLSDIDMFASKEFKMWYEVWKERLKSQNQSSEESKMLMEKSNPTIIPRNNRVEEALVAAIKDSDYSVMQSLLDVLKNPYDYSSINEYYSIVPKSTSCTYKTYCGT
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: RL17_MYCMS
Sequence: MSYIQKRGQNTAWRTALMRNLTTELIINESLEVTQTRAKELRRHFDHMITLAKRGDLHSRRQAASWLRDIDADKKETALQKLFNKLAKKYENRNGGYTSILKLDNRKGDNAPMVIIKLI
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: PPARG_MOUSE
Sequence: MGETLGDSPVDPEHGAFADALPMSTSQEITMVDTEMPFWPTNFGISSVDLSVMEDHSHSFDIKPFTTVDFSSISAPHYEDIPFTRADPMVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNRPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKNIPGFINLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKNLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKVLQKMTDLRQIVTEHVQLLHVIKKTETDMSLHPLLQEIYKDLY
What is the function of this protein?
Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids.  Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase.  It therefore controls the peroxisomal beta-oxidation pathway of fatty acids.  Key regulator of adipocyte differentiation and glucose homeostasis.  ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer.  Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated pro-inflammatory responses.  Plays a role in the regulation of cardiovascular circadian rhythms by regulating the transcription of BMAL1 in the blood vessels (PubMed:19041764).
What are the official names of this protein?
Peroxisome proliferator-activated receptor gamma, PPAR-gamma, Nuclear receptor subfamily 1 group C member 3.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Redistributed from the nucleus to the cytosol through a MAP2K1/MEK1-dependent manner (By similarity). NOCT enhances its nuclear translocation.
Protein: CD017_MACFA
Sequence: MNMNLNPPTSALQIEGKGSHIMARNVTCFLVRHTPHPRRVCHIKGLNNIPICTVNDDENAFGTLWGAGQSNHLEKNRIPFAQCSYPPSTAVQDSPVRGVSPAPNSAKVPPRPHSEPSRKIQECFKTSNENPLVIKKEEIKAKSPPSPPKACSTPGSCSSGMTSIKNDVKANTICIPNYLDQEIKILAKLWDILHTDSLAEVLQWLLHASSKEKEWVSALIHSELAEINLLTHHRRNTSMEPAPETGKPPTVKSPPTVKLPQSALAKSKVLTRDTEGHQPTRVSSQGSAENKEVPKG
What are the official names of this protein?
Uncharacterized protein C4orf17 homolog.
Protein: CAPSD_GOCV
Sequence: MPLYRARPRSLYSRRRRATNRRRRYRRRRLHIGRIRSKYTIFNVKQTQNISFTFFGTGSPDKNKWQAMSLEAVQSSGTSPKPGINLRFAVFGDRLPGTGNQYHYPFDYYMIRMVKVELRPAFNPFQRVRTQGSTYIDKEGNITTTTSGGEWNVDPYAAMSSRKTWSPHRYHKRVFVPKPTIQQGGTGTNIWSTWYTPGGRQLWLNSIQDNVVFYGMGMSLRQAEDTAAPLTVEATITYYIRFGQWTGLSP
What is the function of this protein?
Self-assembles to form the virion icosahedral capsid with a T=1 symmetry.  This very small capsid (17 - 22 nm in diameter) allows the virus to be very stable in the environment and resistant to some disinfectants, including detergents.  Essential for the initial attachment to heparan sulfate moieties and chondroitin sulfate B of the host cell surface proteoglycans.  After attachment, the virus is endocytosed and traffics to the nucleus.  The capsid protein binds and transports the viral genome and Rep across the nuclear envelope (By similarity).
What are the official names of this protein?
Probable capsid protein.
What is the protein family that this protein belongs to?
Belongs to the circoviridae capsid protein family.
What are the subcellular locations of this protein?
Host nucleus. Virion.
Protein: KPRS4_ORYSJ
Sequence: MEVVVARQPKAKKQINLFYCSECEELALKVAASSDTIHLQSINWRSFDDGFPNLFINNAHDIRGQHVAFLASFSSPSVIFEQISVIFALPKLFIASFTLVLPFFPTGSFERVEEEGDVATAFTLARILSMIPKSRGGPTSVVIYDIHALQERFYFGDDVLPCFETGIPLLLQRLRQLPDADNITIAFPDDGAWKRFHKLLLNFPMVVCAKVREGDKRIVRIKEGNPEGRHVVIVDDLVQSGGTLRECQKVLAAHGAAKVSAYVTHAVFPKQSYERFTHTNSAGSADKFAYFWITDSCPQTVKAINQQPPFEVLSLAGSIADALQI
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase 4, Phosphoribosyl pyrophosphate synthase 4.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family.
Protein: SSBB_BACSU
Sequence: MFNQVMLVGRLTKDPDLRYTSAGAAVAHVTLAVNRSFKNASGEIEADYVNCTLWRKTAENTALYCQKGSLVGVSGRIQTRSYENEEGVNVYVTEVLADTVRFMDPKPREKAAD
What is the function of this protein?
Not essential for replication of the chromosome, but is required for optimal competence (PubMed:14762004).  Binds ssDNA, binding is facilitated by DprA, acts as an accessory factor for homologous DNA strand exchange (PubMed:25138221).
What are the official names of this protein?
Single-stranded DNA-binding protein B, SSB B.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes mostly to the cell poles during the development of competence (PubMed:16009133, PubMed:17630974). Colocalizes with ComGA (PubMed:16009133). During competence a number of proteins (at least CoiA, ComFA, ComGA, DprA, RecA and SsbB) are thought to colocalize at the cell pole (PubMed:17630974). During development of competence ComGA and SsbB colocalize in discrete foci which accumulate at the cell poles and then delocalize without the overall levels of proteins decreasing, these processes are coincident with the timing of transformability and the site of DNA uptake (PubMed:16009133).
Protein: FPR1_PODAS
Sequence: MAAFNFEAFSLTPQGSTISAAPRPAAPAIDRTVQQQCGSFGYGNRAFQFDFASLESLPEDANPGLTEVLTAKYWNHFSIQLGHWNTLKVIVLDAQMFSIMPDHTKKGVLNTMKSYLGGADAMYARDADNGQVVILAPRRLMESNITIVGSTTVWDPKKRHVQATAEAKIPRPPNAYILYRKDQQAALKAANPGIPNNDISVMTGGMWKKESPEVRAEYQRRASEIKAKLMSAHPHYRYVPRRSSEIRRRAPRRNRAQEVANASPIGENSGAPIVGNPIVTTMEQQQPLPDISIAPNQEITKDNDVSHLIDPPHVFSGQITELMPDVANFLPPMIREGWSPLHDFRAVLNGHTGNNGVDCALTPESESQDDFVGTPSSTMPDNSAFDWITGTEEDLAQIFGQF
What is the function of this protein?
Controls fertilization, probably by determining the mating type.
What are the official names of this protein?
MAT+ sexual cell fertilization-promoting factor.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1560_LISMC
Sequence: MLIHEISENEKPREKLQNYGIEALSSSELVALIIETGTKNESVLTIANRIIMKFKNVGEMQYASIEEFQLVNGIGIAKASKIMAAIELGRRIGIVTEQEEVVVRCPEDAVKLVMPELAFLFQEHFHCLFLNTKNQVIYRQTIFVGGLNASIVHPREVFRLALRKSAASIMCFHNHPSGDPTPSSEDLLVTKRLAEAGNIVGITLLDHIIIGKNKYISLKEKGYF
What are the official names of this protein?
UPF0758 protein Lm4b_01560.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: EX7S_ENT38
Sequence: MPKKNDAPASFETALNELEQIVNRLESGDLPLEDALNEFERGVQLARQGQVKLQQAEQRVQILLSDSEDAAPTPFTPDAE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FNKD_DICDI
Sequence: MDIISTTFDQINTHIKFTNQKKIEFQNHIEKEWEIITQLESNEQFTVYMSKKLKGPNFTNNRFGLCTVKKIKSQYFNENEILNHIKLRDNKYVLKYYGCGKDNNQDVYIYLEFIEYSIPISKVKLIPNDSSIDNFNNVSNTIIELVTCKLVESLNCIHKDNKIVHGNIKGENILLVNDESEYGFSVKFINFSLNIGYEDSIHLDMFNLGCVLIQMLGCDCTKDENIDFLFSKIPNHLVEKFKKVISQLLSKNINNQILTDIISNKITTSLPKYSTLIGEPNDGLIYIGIQNNSDGLILPLFNQPICKKTFTYGVYYLSLSSFHRQLNVGVIPESIHTLELASFNQTILPGVIPTSVRTLKLPSYNKTLTQGSIPKGVRTLLLSSFNQPLTTDIIPKTVTILKLQSFNQPIEWGALPCSLVELSLASYKQPLQWGVIPYYISTLELPLASAPFSEGSIPSGVSKLIQQGEIQQINKPIKINNENNQNYMSCSQNEFDSKLTLILNSKITRESLFFGLKYLELSTFNQSFETLPIPETVEYLKLPMYNQPLTPKLLPSGIKFLILPSFNHPIRGESIPPSVIHLVFNKLFSVIESIPSSVKYLDLGDEYYVYPGHLLHSVLSFRSGLKFRVTDPIPYSQSLTNLNLYNFNIELLKNGISSNVTSLTLGSNFTNIESLSNLPSSVTNLSFGITTLNEKAISDITKYVKSTVTTITVNNEQIRKKIN
What are the official names of this protein?
Probable inactive serine/threonine-protein kinase fnkD, FNIP repeat-containing protein D.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family.
Protein: DAPE_PELUB
Sequence: MPTYNEITLAKELIRFPSITPIDAGVMKFLAKKLTTIGFKCKILEFKDKNSKPVKNLYARLGNTQPNFMFAGHLDVVPPGNIQDWTIKPFSPTIKKNHLIGRGANDMKSAIASWVVAVNNYVLTNKKINGSISLLITGDEEGVAINGTKKVVDYLKKKKEKIDFCLVGEPTNPNKLGEMIKIGRRGSINAELTIIGTQGHVAYPHRAKNPSTSLIKILNEIKEIKFDKGTKDFQPTNLEVTKININNTADNVIPGLARATFNIRFNNKHTSSSLKNRLNKIFKKITKKDKSNFKVEYRVSGEAFLTKPNKTTYMIQDVIKKITKIKPQLSTTGGTSDARFIRKIAPCLEFGLVGKTMHKVDEAVSISDLKKLTKIYSEILKNYF
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: PYRG_ACIBC
Sequence: MTHFIFVTGGVVSSLGKGISAASVAALLEARGLKVTMVKMDPYINVDPGTMSPFQHGEVFVTEDGAETDLDLGYYERFLRRAKMTKLNNFTSGRVYQDVLNKERRGDYLGGTVQVIPHITDNIKERVLRAGEGYDVAIVEIGGTVGDIESLPFMESVRQLMVELGHKRTMLMHLTLLPYIKSAAELKTKPTQHSVKELLSIGIQPDILICRTEYDVDADTKRKIALFTNVEARAVVVCKDAKTIYQIPRGFYEQNVDDLICERFGFTDLPEADLTDWDNVVEALLNPEYTVRVAMVGKYVELPDAYKSVNEALLHAGIKNRVKVQIDYVNAEELESQDVSILKTADAILVPGGFGERGTEGKMKAIQYARENSIPFLGICLGMQLAVIEYARHVAGMPEASSTEFNRSTKYPLIGLITEWLDERGELQQRSLESDLGGTMRLGAQKSELVEGTKTREVYGKAEITERHRHRYEMNNRFIEAIEQAGMKISGYSSAQHLVETVEIPEHPWFIAVQFHPEFTSSPRDGHPLFASFIDAAKTQHQKSK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: RDRP_SHVX
Sequence: MTAVQKLFDQISDPNTKAGYSNACFEAAQRRPKKAMAIAPFSVTTPEALTLERFGITTSPFATTSHTHAADKIIENDCLTIIGHYLPKREAVTLIQLKRSKIHLLGRQPSQDNFQNYCHEPKDVLRYGITHPNSCPVVNTEYAVLADTLHFMSPRQLYHLFSRNPKLERLFATLVLPIEAQHRLPSLFPDVYRLEYYKDHFAYMPGGHGGGAYVHSYGTLKWLDTAQVGPVDYTKSSITNPWPITDYLSIEKIETKAAHHIMFIQRTRAQVDWPLPPIWVYHASEYVKLPLIFYPPEANVQKTYPHTLIKRMQLYCFSVKAVSLRDIFAKLRQVIETQELVRYSMADLIRLANYFLFITGMNQVSDYESPLLENLFGKMCASIRMRLRTFFQNLLGKTSYAALLTVTDVIPVHFTTQPKRREAVGELWFQEPKWSVSTMTQPRKEHHRLQMTWTLLAWFHQLESSGSMSEPCNNSESTPQRTATSQQKAAKLTTSQKHNRRTDQTTMNPQYPPLMLTIAPMMPRHSLMKKTIATPCRTLEEISDLDLDDFDDLPNEASNEPPSANEQSPDNHAETTTRGVFPCECGTEITVNSFGRAIEVAGVNLTDHMKGRLAAFYSRDGQGYSYTGYSHKSQGWLEGLDKLIEACGEKPTTYNQCLVQKYEQGSRIGFHSDEQAIYPKGNKILTVNAAGSGTFGIKCAKGETTLNLEDGDYFQMPSGFQETHKHNVVAVTPRLSFTFRSTVVNSQKKPAEPEKLNQNNACPKPSDPSNASGKQHKKTHPAKGNEKSSSPNLEPLDAPTVEILKLHGFTALTPQHDGTCQIRPVYFNKDIHLRRKAVKTDMSPPARPFFDLATSLHRGIYTHKIDNRRATAYMSDVKNNLTGLVLPKLDRDLLSSWVALAETTTREVAVLAIHGAGGAGKSRALQELLRSSPELADSINIVVPTINLANDWKAKLPQMDPRRVMTFQKACERECKSVTIFDDYGKLPAGFVDAYLAIKVNVELAILTGDQRQSTHHQERESQISSLQSNIAQFSKYADYYLNATHRQPRRLANPIKVHAERQLGGAVLKANIVPDLAMVLVPAFRSQSLLTDLGRHAMTYAGCQGLTLNHLTIILDKDTPLCSDEVLYTAFSRASESITFVNTHSDNPAFLAKLDATPYLKTLISWVREDEEAGADCPATEPLVKDVPTKTHIPVANDKVQLEGKIEAMEDKDTRELWSGEEKTNLMQTQDPVVQLFPHQQAKDEALFKITIGERIRMATPEQNAKQLRHTLNAGDLLFEAYAQFMKVPKETQPFDKRLWTHCRQLALRTYLSKPTSNLQQGARQDPDFPDNAIALFNKSQWVKKLEKVGARFKAGQTISAFKQEVVLLTTTMALYLRKKREQHQPDNVFIMCERTPEQFNAFVMTKWDFDRPNYTSDYTQYDQSQDAAFLNFEIRKARHLGVPEDVLSFYKFIKTHAKTFLGNLAIMRLSAEGPTFDANTECNIAYDALRFRLGDDVRASYAGDDLVRDKACEERAGWVYSESLFSLKAKPLVTNKPDFCGWRLTRHGIVKSPIQLYQSLQLALRLGKIDEVKRSYAIDYLFAYRLGDKIYDIFDEDELEKHQLVTRTLIKKGMQPPESGNHLPIFHITSDRLIRDPDAVKVQSYECDRILLKQPHIIDDYIPAGTQPRNTEHPASADRRDMTRACNLSAEKLAFGGNTINHLFRTSWEGRSPLSN
What is the function of this protein?
RNA replication.  The central part of this protein possibly functions as an ATP-binding helicase (Probable).
What are the official names of this protein?
RNA replication protein, 194 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the potexvirus/carlavirus RNA replication protein family.
Protein: SYGA_PECAS
Sequence: MQKFDTKTFQGLILTLQDYWARQGCTIVQPLDMEVGAGTSHPMTCLRALGPEPMATAYVQPSRRPTDGRYGENPNRLQHYYQFQVVIKPSPENIQELYLGSLKELGMDPTIHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECKPVTGEITYGLERLAMYIQGVDSVYDLVWSDGLLGKTTYGDVFHQNEVEQSTYNFEHADVDFLFSCFEQYEKEAQHLLALEKPLPLPAYERILKAAHSFNLLDARKAISVTERQRYILRIRTLTKAVAEAYYASREALGFPMCNKKES
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSKI1_RAT
Sequence: MGKEQELVQAVKAEDVGTAQRLLQRPRPGKAKLLGSTKKINVNFQDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSAVNVPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCIVDNSGKTPLDLACEFGRVGVVQLLLSSNMCAALLEPRPGDTTDPNGTSPLHLAAKNGHIDIIRLLLQAGIDINRQTKSGTALHEAALCGKTEVVRLLLDSGINAQVRNTYSQTALDIVHQFTTSQASKEIKQLLREASAALQVRATKDYCNNYDLTSLNVKAGDIITVLEQHPDGRWKGCIHDNRTGNDRVGYFPSSLGEAIVKRAGSRTGSEPSPPQGGGSLGPSAPPEEIWVLRKPFAGGDRSGSLSNVAGGRSTGGHALHAGAEGVKLLATVLSQKSVSESSPGDSPVKPPEGSSGAARSQPPAAHAGQVYGEQPPKKLESSSASEGKSAEAVSQWLATFQLQLYAPNFTSAGYDLPTISRMTPEDLTAIGVTKPGHRKKITAEISGLNIPDCLPEHKPANLAVWLSMIGLAQYYKVLVDNGYENIDFITDITWEDLQEIGITKLGHQKKLMLAVRKLAELQKAEYSKYEGGPLRRKAPQSLEMMAIESPPPSEPAAAECQSPKMTTFQDSELSGELQAALSGPAEAGAAAAEKSSNHLPATPRTTSRQESSLSGRARHMSSSQELLGDGPQGPGSPMSRSQEYLLDEGPAPGTPPKEVRSSRHGHSVKRASVPPVPGKPRQVLPSGVSHFTPPQTPTKAQPGSPQALGGPHGPATAKVKPTPQLLPPTDRPMSPRSLPQSPTHRGFAYVLPQPVEGEAGPPAPGPVPPPVPAAVPTLCLPPEADVEPRRPKKRAHSLNRYAASDSEPERDELLVPAAAGPYATVQRRVGRSHSVRAPAGTDKNVNRSQSFAVRPRKKGPPPPPPKRSSSAMASANLADEPSPDVETEDGRLGVRAQRRRASDLAGSVDTGSAGSVKSIAAMLELSSIGGGGRAIRRPPEGHPTPRPASPDPGRVATVLASVKHKEAIGPDGEVVNRRRTLSGPVTGLLATARRGPGEPAEQSHFMEDGTARQRLRGPAKGEAGVEGPPLARVEASATLKRRIRAKQSQQENVKFILTESDTVKRRPKAKEPDIGPEPPPPLSVYQNGTATIRRRPASEQAGPPELPPPPPPAEPPPTDLMPLPPLPLPDGSARKPVKPPVSPKPILAQPVSKIQGSPTPASKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPTAPKPAKALAGLQSSSATPSPVPSPARQPPAALIKPASSPPSQSASPAKPPSPGAPALQVPTKPPRAAASVVSGPPVASDCASPGDSARQKLEETSACLAAALQAVEEKIRQEDGQGPRPSSIEEKSTGSILEDIGSMFDDLADQLDAMLE
What is the function of this protein?
May link the scaffolding protein CASK to downstream intracellular effectors.
What are the official names of this protein?
Caskin-1, CASK-interacting protein 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCJV_ECO57
Sequence: MAQLSLQHIQKIYDNQVHVVKDFNLEIADKEFIVFVGPSGCGKSTTLRMIAGLEEISGGDLLIDGKRMNDVPAKARNIAMVFQNYALYPHMTVYDNMAFGLKMQKIAKEVIDERVNWAAQILGLREYLKRKPGALSGGQRQRVALGRAIVREAGVFLMDEPLSNLDAKLRVQMRAEISKLHQKLNTTMIYVTHDQTEAMTMATRIVIMKDGIVQQVGAPKTVYNQPANMFVAGFIGSPAMNFIRGTIDGDKFVTETLKLTIPEEKLAVLKTQESLHKPIVMGMRPEDIHPDAQEENNISAKISVVELTGAEFMLYTTVGGHELVVRAGALNDYHAGENITIHFDMTKCHFFDAETEIAIR
What are the official names of this protein?
Uncharacterized ABC transporter ATP-binding protein YcjV.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: ISPH_CHLTR
Sequence: MRKIILCSPRGFCAGVIRAIQTVEVALEKWGRPIYVKHEIVHNRHVVDKLREKGAIFIEDLQEVPRNSRVIFSAHGVPPSVREEAEERGLIAIDATCGLVTKVHSAVKMYAKKGYHIILIGKRKHVEIIGIRGEAPDQITVVENIAEVEALPFSAQDPLFYVTQTTLSMDDAADIVAALKARYPRIFTLPSSSICYATQNRQGALRNILPQVDFVYVIGDTQSSNSNRLREVAERRGVTARLVNHPDEVTEEILQYSGNIGITAGASTPEDVVQACLMKLQELIPDLSIEMDLFVEEDTVFQLPKEL
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: MDM10_KLULA
Sequence: MLEYMDYVLRQFEECTSWNKDNSYENIVGTSRNILQFDIPTALKVQVSNRATPYSYNTLELTNNKTINGSLTYLYTNCENLDQFIEGSSSVHLQQMTQSFRYIEPYYHHYKNNSKLEVPKVPELPISLAYGRMFYPSSSLEAMYIRRFPNYYQFILKCSSSKSGSSILTMYLQKNTGINCQELIFSTNEALLGYRFVHNFVSAGSKSNLSLYNNSSLSIGSEIWCALLNLSPGCSTTLRYCSHATNTGKPLIFTLSLNPLYGHVSSTYSIKTHENLTFCTKYDFNIYSIQSNLTLGMELWKNSSSIPVERPSEPVETIEDWPQLSHDKTPMYYHLLTRTENSGASSQRLLKDLNLTFQSSLQKINKERNVIENFNERYSEANFTQVFKVSTSLRDMNLRLLWEGKIRGFLISAGAELTQPPEISTNGLDSLEHQNWSLISPSKFGIQLQYSA
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange.  MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex).  Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins.  Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins.  May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway.  Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 10, Mitochondrial inheritance component MDM10.
What is the protein family that this protein belongs to?
Belongs to the MDM10 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria- endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: SIXA_ECOLI
Sequence: MQVFIMRHGDAALDAASDSVRPLTTNGCDESRLMANWLKGQKVEIERVLVSPFLRAEQTLEEVGDCLNLPSSAEVLPELTPCGDVGLVSAYLQALTNEGVASVLVISHLPLVGYLVAELCPGETPPMFTTSAIASVTLDESGNGTFNWQMSPCNLKMAKAI
What is the function of this protein?
Exhibits phosphohistidine phosphatase activity towards the HPt domain of the ArcB sensor involved in the multistep His-Asp phosphorelay.
What are the official names of this protein?
Phosphohistidine phosphatase SixA, RX6.
What is the protein family that this protein belongs to?
Belongs to the SixA phosphatase family.
Protein: ACCO_ACTDE
Sequence: MEAFPVIDMEKLNGEERAPTMEKIKDACENWGFFELVNHGISHELMDTVERLTKEHYNKCMEQRFKEMVATKGLEAVQSEINDLDWESTFFLRHLPVSNISEIPDLEQDHRKAMKEFAEKLEKLAEQLLDLLCENVGLEKGYLKKAFYGSKGPTFGTKVSNYPPCPRPELIKGLRAHTDAGGIILLFQDNKVSGLQLLKDGEWIDVPPMKHSIVINIGDQLEVITNGKYKSVMHRVIAQPDGNRMSIASFYNPGSDAVMYPAPALVDKEEDQQKQVYPKFVFEDYMKLYAGLKFQAKEPRFEAMKAMENAVNLGPIATI
What are the official names of this protein?
1-aminocyclopropane-1-carboxylate oxidase, ACC oxidase, Ethylene-forming enzyme, EFE.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: YFP8_SCHPO
Sequence: MNFVSSILIRWCDVPVYILLRKCVIYKFAYSSRKIESVHCAITDDEVMSYNNEDMVPFSAINLPIRFLIFYNAFRSNTSWNYNESQIGNLTISKQS
What are the official names of this protein?
Uncharacterized protein C7D4.08.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RUVC_DESHY
Sequence: MLILGIDPGTAIMGYGLIEKKGNRLFPVDYACWRTPAHTPMPERLLMLYHEIEAYIKEKQPHHVAVEELFFNRNTTTAISVGQARGVVLLAAAQCGLPVYEYTPLQVKQAVAGYGRADKQQIQQMVRALLGLQEIPKPDDTADALAIAICHAHSVNLLNRMGGAL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: REPEA_BPT4
Sequence: MVILLHKFQLDELIYIVLAQGYHQIPEYVRFQFPLYAHKDIHLYMKKLVL
What is the function of this protein?
Involved in T4 DNA replication.  Binds to ssDNA.
What are the official names of this protein?
DNA replication protein repEA, DNA-binding protein dbpB.
Protein: PUR9_JANMA
Sequence: MIKQALISVSDKTGVLEFARALSGMGVNILSTGGTAKLLAENGISVTEVADYTGFPEMLDGRVKTLHPKVHGGILARRDFAEHVSALEKHNIPTIDMVVVNLYPFQQTVAREHCSLEDAIENIDIGGPAMLRSSAKNHKDVIVICDPTDYSQVLGELSANQGEVSYETKFTLAKKVFAHTAQYDGAITNYFTSLGADKQHATRSSYPATLNLHFEKVQEMRYGENPHQSAAFYRESNPQVGALANYTQLQGKELSYNNIADADAAWECVKTFDESACVIIKHANPCGVAVGASPLEAYSKALQTDPTSAFGGIIAFNRELDGNAAEAVAKQFVEVLIAPSFSEKAKQIFAGKQNVRLLEIPLGNAVNAHDFKRVGGGLLVQSPDAKNVVLAELKVVSKKQPTPQQLQDLMFAWRVAKFVKSNAIVFCANGMTMGVGAGQMSRIDSARIASIKAQNAGLSLVGTAVASDAFFPFRDGLDVVVAAGATSVIHPGGSMRDQEVIDAADEQGVVMLMTGTRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.