PharMolix/UniProtQA huggingface dataset:
Protein: ISPG_ACIAD
Sequence: MIENPIKRRPTRKIRVGSVYVGGDAPISIQSMTNTETCDVDATVAQIQRCADAGVDIMRVSVPSMEAAEAFGKIRQRVSVPLVADIHFDHRIALAVADYGADCLRINPGNIGSDQKVREVVAAARHHGISIRIGVNAGSLEKDLQKKYGEPTGAALLESAMRHIDILDRLDFHEFKVSVKASNVFLTMDAYRLLSQQIDNPLHLGVTEAGIYRTGTVKSAIALGGLLMEGIGDTMRISLAAEPEDEVKIGFDILKSLGLRSNGINFIACPSCSRQEFNVIKVMQALEERLEDIRTPMDLSVIGCKVNGPGEAKEADIGIVGASPRSLVYRNGEKSHLIDTDQLVDEIEDMVRQRVKEIEEAKSKEIIRSSS
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: GCS21_SACEN
Sequence: MLDLTLGVEEEFLLLDPGTLEPAAAADRFRAETDRGEVHRELAPAQIESATAVCRTLEELHHDLSGLRRALAADAAEQGYRLASVGVPPIGSAGPPPVTDSPRYRRMYETYGSIIEDQGVCGCHVHVGALDLETALVAGNHLRPWLPALLLLTTNSPFFRGGDTGYASWRTTLWSRWPAAGPPPVLTSARHYHYVVDCLLASGAVLDSGMLYWYARPSHRVPTLEVRVADAAATVDEAVLLAGLVRGLVGVALSDRPGPVRPVDDAVLRAACWCSAHHGLEGFSLDVGTGRLVPSWHLVDDLVEHVRPVLERYGDLDAVRALLAKLRENGSAARRQREVFRRHRDIGEVVEHVLVETVPDENAALPGRSISPSA
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2-1, Gamma-glutamylcysteine synthetase 2-1, GCS 2-1, Gamma-GCS 2-1.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: PDXH_SHEB5
Sequence: MTDLSDIRREYAKGGLRRADLPQNPMDLFELWMTQARDAELSDPTAMCVATVDEHGQPFQRIVLLKRFDDTGFVFFTNLGSRKAQQIAANNKVSLHFPWHPLERQVSVLGEAQALSTAEVLKYFMTRPKDSQIAAWVSQQSSKLSARQVLEGKFFEMKAKFAKGDVPLPSFWGGYLVRPSSIEFWQGGEHRLHDRFIYTRHDAEWEIDRLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: SD16_ARATH
Sequence: MRNVPNYHHSYFILFIIILFLAFSVYASNFSATESLTISSNKTIISPSQIFELGFFNPDSSSRWYLGIWYKIIPIRTYVWVANRDNPLSSSNGTLKISDNNLVIFDQSDRPVWSTNITGGDVRSPVAAELLDYGNFVLRDSKNNKPSGFLWQSFDFPTDTLLSDMKMGWDNKSGGFNRILRSWKTTDDPSSGDFSTKLRTSGFPEFYIYNKESITYRSGPWLGNRFSSVPGMKPVDYIDNSFTENNQQVVYSYRVNKTNIYSILSLSSTGLLQRLTWMEAAQSWKQLWYSPKDLCDNYKECGNYGYCDANTSPICNCIKGFEPMNEQAALRDDSVGCVRKTKLSCDGRDGFVRLKKMRLPDTTETSVDKGIGLKECEERCLKGCNCTAFANTDIRNGGSGCVIWSGGLFDIRNYAKGGQDLYVRVAAGDLEDKRIKSKKIIGSSIGVSILLLLSFIIFHFWKRKQKRSITIQTPIVDLVRSQDSLMNELVKASRSYTSKENKTDYLELPLMEWKALAMATNNFSTDNKLGQGGFGIVYKGMLLDGKEIAVKRLSKMSSQGTDEFMNEVRLIAKLQHINLVRLLGCCVDKGEKMLIYEYLENLSLDSHLFDQTRSSNLNWQKRFDIINGIARGLLYLHQDSRCRIIHRDLKASNVLLDKNMTPKISDFGMARIFGREETEANTRRVVGTYGYMSPEYAMDGIFSMKSDVFSFGVLLLEIISGKRNKGFYNSNRDLNLLGFVWRHWKEGKELEIVDPINIDALSSEFPTHEILRCIQIGLLCVQERAEDRPVMSSVMVMLGSETTAIPQPKRPGFCVGRSSLEVDSSSSTQRDDECTVNQVTLSVIDAR
What is the function of this protein?
Involved in the regulation of cellular expansion and differentiation.
What are the official names of this protein?
Receptor-like serine/threonine-protein kinase SD1-6, Arabidopsis thaliana receptor kinase 2, S-domain-1 (SD1) receptor kinase 6, SD1-6.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: PFKA_BACCZ
Sequence: MKRIGVLTSGGDSPGMNAAIRAVVRKAIFHDIEVYGIYHGYAGLISGHIEKLELGSVGDIIHRGGTKLYTARCPEFKDPEVRLKGIEQLKKHGIEGLVVIGGDGSYQGAKKLTEQGFPCVGVPGTIDNDIPGTDFTIGFDTALNTVIDAIDKIRDTATSHERTYVIEVMGRHAGDIALWAGLADGAETILIPEEEYDMEDVIARLKRGSERGKKHSIIVVAEGVGSAIDIGKHIEEATNFDTRVTVLGHVQRGGSPSAQDRVLASRLGARAVELLIAGKGGRCVGIQDNKLVDHDIIEALAQKHTIDKDMYQLSKELSI
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXS_COREF
Sequence: MGILNSISTPADLKALAEEDLEVLAGEIRSFLVDKVAATGGHLGPNLGVVELTIGLHRVFDSPREPIIFDTSHQSYVHKILTGRGDAFDTLRQKGGLSGYTSRAESEHDWTESSHASAALSYADGMSKAFQLDGDTNRNVVAVVGDGALTGGMCWEALNNIAAGKDRNVVVVVNDNGRSYSPTIGGFAENLAQLRMEPFYDRVMEQGKSTLKSMGWVGERTFEALHAFKEGVKSTVIPTEMFPELGMKYIGPVNGHDQKAVDNALAYARDFKGPIIVHVVTEKGRGYAPAERDLDELMHATGVMDPRTGIPVAASKPGWTAAFSEELVKLGGRREDIVAITAAMAGPTGLAKFAANFPSRFYDVGIAEQHALTSAAGLALAGKHPVVAIYSTFLNRAFDQLLMDVALLNLPVTVVLDRSGVTGSDGASHNGVWDLALTSIVPGIRVAAPRDEDTLRELLGEAVDINDGPSVVRFPKGDLPAPIEAIETLEDGVDILAYLEASPASEDAPDLLIVAVGERATLALELGERLVAAGANVTVVDPRWVIPIPQSLVALAADHDLVITIEDGVIHGGVGSLLSDALNAAEVDTPRRQVAVPQKFLDHASRGQVLLDHDLDIDSVEKTALGWMDRLFGGGN
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: NINB_BPP21
Sequence: MKKLTFEIRSPAHQQNAIHAVQQILPDPTKPIVVTIQERNRSLDQNRKLWACLGDVSRQVEWHGRWLDAESWKCVFTAALKQQDVVPNLAGNGFVVIGQSTSRMRVSEFAELLELIQAFGTERGVKWSDEARLALEWKARWGDRAA
What are the official names of this protein?
Protein ninB.
What is the protein family that this protein belongs to?
Belongs to the ninB family.
Protein: TOP1_RICFE
Sequence: MKLVIVESPAKAKTINKYLGDEFKVIASFGHIRDLPSKKGSVLPDENFAMKYDISDKAGKYVDAIVKDAKKADAVYLATDPDREGEAISWHVAEVIKEKNKVKSDDFFKRVAFNEITKKAIIHAVENPRKLDANLVNAQQARRALDYLVGFTLSPLLWRKLPGCKSAGRVQSVALRLICEREDEIERFKSEEYWDISLKMQNSNNELFTAKLTHVNDQKLEKFSIINEKDAKDLTEKLKSQNFHVDKIEKKQQKRQPQPPFITSSLQQEAARKLGFSAKKTMQIAQKLYEGVDIGKETIGLITYMRTDGVTLSNDAIADIRKLIDKNYGDKYLPNSPRIYKSKVKNAQEAHEAIRPTNITYTPDSLKEKLEKDYYKLYELIWKRTIACQMENVIMDLVVASLASENKEYLAKANGSTIAFDGFYKVYRESVDDEAEEENKMLPPLKEQEPLKTKEIIPNQHFTEPPPRYSEASLVKKLEELGIGRPSTYASILSVLQDRKYVSLEKKRFMPEELGRLVTVFLVGFFKKYVEYDFTAGLENELDEIAAGKLEWKAALNNFWSGFNHNIESVNEQKITEIISYVQKALDYHLFSENKESKACPSCKTGELSLKLGKFGAFLACSNYPECTFRKSIVSGNDNNENDGDLAATPNENKVLGTDKDGIEIYLKKGPYGPYVQLGEQEGKVKPKRSPVPASLNQNDITLEMALKLLSLPLKIGIHKDSGEEIMIGYGKFGPYIKYMGKFISIPKKYDFLNLSLDDAMKLIEDNKAKLEKKQA
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.  The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils.  Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.
What are the official names of this protein?
DNA topoisomerase 1, DNA topoisomerase I, Omega-protein, Relaxing enzyme, Swivelase, Untwisting enzyme.
What is the protein family that this protein belongs to?
Belongs to the type IA topoisomerase family.
Protein: AGAL2_PEDPE
Sequence: MPVEYDPKTGLINLHNDQISYVIQILAHRYPVHRYFGRYFSKQPYFEPMPSGSHAFANDPTERFPYSVTSLPLEYSTIGSGDYRQPAYVIKDANNQLLPILEYTGFSVNDQPINSRQLPPTVSKHTPVTTLVIHLTDAVTKLQMDLNYTIFENQPLILRSTTLRHHGTTNLQVTALSSAQLDLPTDQYTALTLSGTHAHEANPSFNRLHPGLQTVRSLRGTSGPQHQPFMALAEPNTTELAGTVIGCALAWSGNFDSTVEVDQYQHSRLTIGLEPDTFEWQLKPNSSFQTPEAVLTWTNTGFNGMSQVFHDFSYQLMPSQTNIPSVLNTWETLTFAVSESKVQHLIEHAHQLGLQMLVLDDGWFVNRNGENGQLGDWFVDPIKFPNGLNPLAQQAHHHRMKFGLWVEPEMITTNSQLYQQHPDWVLQYVDRTPITARHQLVLDLSQAAVRDHLITTLTNLVQNNQLDYLKWDMNRHLTQVGSTHLPAAQQGELYHRYVCGLYDILTRLKRACPKLIIENCSAGGGRFDFGMLPYTNQTWISDLTDPVDRATIENGFSYLFPPRIFSNHITASPNAQNGRITPFETRLQLACIGQLGLELNPKQLAPSEQQLLRGALIKYQQLKSTFIKAHFYRLPTTRHVVAWLIVTADKKQAICCYLNGLNSRVKTQHPLPLHYLDAELAYSDSSGNRYTGHQLNTMGIPLKPTNADFTSQLIYLCQN
What is the function of this protein?
Alpha-galactosidase associated with the sucrase operon.
What are the official names of this protein?
Alpha-galactosidase 2, Melibiase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 36 family.
Protein: TMOD1_RAT
Sequence: MSYRRELEKYRDLDEDEILGALTEEELRTLENELDELDPDNALLPAGLRQKDQTTKAPTGPFKREELLDHLEKQAKEFKDREDLVPYTGEKRGKIWVPKQKPMDPVLESVTLEPELEEALANASDAELCDIAAILGMHTLMSNQQYYQALGSSSIVNKEGLNSVIKPTQYKPVPDEEPNPTDVEETLERIKNNDPELEEVNLNNIRNIPIPTLKAYAESLKENSYVKKFSIVGTRSNDPVAFALAEMLKVNKVLKTLNVESNFISGAGILCLVEALPHNTSLVELKIDNQSQPLGNKVEMEIVNMLEKNTTLLKFGYHFTQQGPRLRASNAMMNNNDLVRKRRLADLTGPIIPKCRSGV
What is the function of this protein?
Blocks the elongation and depolymerization of the actin filaments at the pointed end.  The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton (By similarity).
What are the official names of this protein?
Tropomodulin-1, Erythrocyte tropomodulin, E-Tmod.
What is the protein family that this protein belongs to?
Belongs to the tropomodulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=In myofibrils with sarcomeric structure, localizes to the pointed end of actin thin filaments.
Protein: UNG_STRU0
Sequence: MEHSTWHRKIKESLPPDYFARINQFLDQVYSQGRVYPKREHIFKALTETPYEDLKVLILGQDPYHGPGQAQGLSFSVPDSIAAPPSLQNILKELSEDIGKRDHHDLTSWAKQGVLLLNACLTVPEHQANAHAGLIWEPFTDAVIQLANAKESPVVFILWGGFARKKKAFITNPKHLVIESAHPSPLSAYRGFFGSRPFSKCNAFLKENQLEPIDWLQ
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZSC21_PANTR
Sequence: MMTKVLGMAPVLGPRPPQEQVGPLMVKVEEKEEKGKYLPSLEMFRQRFRQFGYHDTPGPREALSQLRVLCCEWLRPEIHTKEQILELLVLEQFLTILPQELQAWVQEHCPESAEEAVTLLEDLERELDEPGHQVSTPPNEQKPVWEKISSSGTAKESPSSMQPQPLETCHKYESWGPLYIQESGEEQEFAQDPRKVRDCRLSTQHEESADEQKGSEAEGLKGDIISVIIANKPEASLERQCVNLENEKGTKPPLQEAGSKKGRESVPTKPTPGERRYICAECGKAFSNSSNLTKHRRTHTGEKPYVCTKCGKAFSHSSNLTLHYRTHLVDRPYDCKCGKAFGQSSDLLKHQRMHTEEAPYQCKDCGKAFSGKGSLIRHYRIHTGEKPYQCNECGKSFSQHAGLSSHQRLHTGEKPYKCKECGKAFNHSSNFNKHHRIHTGEKPYWCHHCGKTFCSKSNLSKHQRVHTGEGEAP
What is the function of this protein?
Strong transcriptional activator (By similarity).  Plays an important role in spermatogenesis; essential for the progression of meiotic prophase I in spermatocytes (By similarity).
What are the official names of this protein?
Zinc finger and SCAN domain-containing protein 21.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: H2B3_MEDTR
Sequence: MPPTKAEKKPAEKKPAEKAPAEKKPKAEKKISKEGSSDKKKKRTKKSVETYKIYIFKVLKQVHPDIGVSSKAMGIMNSFINDIFEKLAQESSRLARYNKKPTITSREIQTAVRLVLPGELAKHAVSEGTKAVTKFTSS
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Probable histone H2B.3.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: ADT2_ARATH
Sequence: MVEQTQHPTILQKVSGQLLSSSVSQDIRGYASASKRPATYQKHAAYGNYSNAAFQYPLVAASQIATTTSPVFVQAPGEKGFTNFAIDFMMGGVSAAVSKTAAAPIERVKLLIQNQDEMLKAGRLTEPYKGIRDCFGRTIRDEGIGSLWRGNTANVIRYFPTQALNFAFKDYFKRLFNFKKDKDGYWKWFAGNLASGGAAGASSLLFVYSLDYARTRLANDSKSAKKGGGERQFNGLVDVYKKTLKSDGIAGLYRGFNISCAGIIVYRGLYFGLYDSVKPVLLTGDLQDSFFASFALGWLITNGAGLASYPIDTVRRRMMMTSGEAVKYKSSFDAFSQIVKKEGAKSLFKGAGANILRAVAGAGVLAGYDKLQLIVFGKKYGSGGA
What is the function of this protein?
ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell (By similarity).  Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane (By similarity).
What are the official names of this protein?
ADP,ATP carrier protein 2, mitochondrial, ADP/ATP translocase 2, Adenine nucleotide translocator 2, ANT 2.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GLPK_PSYIN
Sequence: MTDKKYIVALDQGTTSSRAVILDHDANIVSVSQREFKQIYPQAGWVEHDPMELYATQSAVLTEILAKESIRSDQIAAIGITNQRETTIVWNRETGIPVYNAIVWQCRRTASICDALKEQPGLEDYIRENTGLVLDPYFSGTKIKWILDNVEGAREDAEAGKLMFGTVDTWLVWKMTQRHVHVTDYTNASRTMLFNINTLKWDEKLLKILGIPLSMMAEVKSSSEVYGQTNIGGVGGTRIPIAGIAGDQQAALYGHMCVEKGQAKNTYGTGCFLLMNTGKEKVTSSNGLLTTLACGPKGEASYALEGAVFMGGASIQWLRDEMKLLADAKDSEYFATKVDSSNGVYVVPAFTGLGAPYWDPYARGTIVGLTRGVNSNHIIRATLESIAYQTRDVLDAMQADSGIKLSALRVDGGAVANNFLMQFQSDVLDTTVQRPAVSEVTALGAAYLAGLAVGYWESLEELAGKAVIEQTFEPHADPVKRKQRYRGWKRAVKCTQAWAEMHDEDFE
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: RL18_METS5
Sequence: MAHGPNYKVKYRRRREGKTNYYRRYTYVLNRSDRVVVRLTNKYVIVQFVKFDPKGDITVAAAHSRELMKFGWKGDENNSTACYLTGYLAGLRAKKAGMTSASADLGLFTPTKGARIFYVLKGVIDSGVKVPMGDVGVNNDRLAGKHIAEYAKKLEQEDPDKYRGLFSRYLARGLDPKDLPAHFKEVLNSIKSGEK
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: DUT_PSEA7
Sequence: MHSLQAKILDPRLGTDFPLPQYATPGSAGLDLRAMLEEDTVLGPGQTLLIPTGLSIHIADPGLAALVLPRSGLGHKHGIVLGNLVGLIDSDYQGELMVSCWNRGESPFTIAVGERIAQLVLVPVVQAHFELVEQFDESQRGAGGFGHSGSH
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: XYNA_NIACI
Sequence: MFKFKKNFLVGLSAALMSISLFSATASAASTDYWQNWTDGGGIVNAVNGSGGNYSVNWSNTGNFVVGKGWTTGSPFRTINYNAGVWAPNGNGYLTLYGWTRSPLIEYYVVDSWGTYRPTGTYKGTVKSDGGTYDIYTTTRYNAPSIDGDRTTFTQYWSVRQSKRPTGSNATITFTNHVNAWKSHGMNLGSNWAYQVMATEGYQSSGSSNVTVW
What are the official names of this protein?
Endo-1,4-beta-xylanase, Xylanase, 1,4-beta-D-xylan xylanohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 11 (cellulase G) family.
Protein: ILVC_SHISS
Sequence: MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVGCGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLVVNLTPDKQHSDVVRTVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKLVEEGTDPAYAEKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADWANDDKKLLTWREETGKTAFETAPQYEGKIGEQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFSYACVPLLKPFMAELQPGDLGKAIPEGAVDNAQLRDVNEAIRCHAIEQVGKKLRGYMTDMKRIAVAG
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: PPK32_SCHPO
Sequence: MLANALRLVSNSKKIKYDYDIQKENSVQVGPWTVYSASKKGTNEEVSVFTFDKKNLSTLLKRGSIDSNLKTNYVLELLRKDVSSLSRLRHPSLLQVVEPLEESKSSMSFVTRRIQSMLQDFIKSSNGGFSNYGSSANGKSSGNALEEVEIQKGLLQIIDGLVFLHGSAKVIHYNIRPSSVVVDAKGDWKLCGFSFSQSVESARYEFNDYDFGIPSSLQQSMDFLAPEYITHEIAGPESDVFSFGCLIYSIFNKNQSIINANNHLLSYEKEITSLNSPTFIESKNLPSENLKSLLKETLAVDPKQRASMFELERSPYFTGSAIAALRFLESFPEKLPSEKVSFMESLSKNLTTFPYRIQSQKILPTLLDHLNDQKLVPSLLPCIFEISKGLDSSIFSSKVFTAIFPIISAANSYPERVPLCIFQYMDCLKSKLPSGEFLSKIVPFIYGCFENSSLNVQTTSIQILGTLLDIIDVTTVKSSICPKLYHSFSVTNQLDVKVAILDTFNVFINQKFLDSFAIVDKLLPVLEKVKTREPTVVMGMVTVYISAGAIIPEETVHEQVIPRLWILSVSPSLSLEQYNKCMREIRSLSDAVQKSHAKKLQSKPSSVVPNRITTDPFSSQTKEATSKPSSISPNKATTNIFTSQASLSSQGVARETSSASSYRSYSQRASTPAVTAKSSFHYATPTSGLSNFNSVTPSSSASLYPPLIPSEARTPSVQPANRRVTTPVVNQNTVTSDSSNDLGGWKSLL
What are the official names of this protein?
Protein kinase domain-containing protein ppk32.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROD_STRPB
Sequence: MRIVAPVMPRHFDEAQAIDISKYEDVNLIEWRADFLPKDEIVAVAPAIFEKFAGKEIIFTLRTVQEGGNITLSSQEYVDIIKEINAIYNPDYIDFEYFTHKSVFQEMLDFPNLILSYHNFEETPENLMEAFSEMTKLAPRVVKIAVMPQSEQDVLDLMNYTRGFKTLNPEQEFATISMGKLGRLSRFAGDVIGSSWTYVSLDHVSGPGQVTLNDMKRIIEVLEMDISN
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: ASSY_SYNFM
Sequence: MDVKKVVLAYSGGLDTSIILKWLIESYGCEVVAFSADLGQAEELDGLEAKALATGAVKARIVDLREEFVRDFVFPAFRANAIYEGQYLLGTSIARPLIAKAQIRIAEEEDADAVSHGATGKGNDQVRFELTYIALNPAIKIIAPWREWDLKSRSDLVEFARRHGIPIPVTKEKPYSSDRNMLHISYEGGILEDPWLEPDPAMFTLSVAPEEAPDAPEFVEIDFERGNPVAVNGERLSPAQLLTRLNALGGRHGIGRVDLVESRFVGMKSRGVYETPGGTIMRTAHHAVESVTMDRELMFLRDSLVPQYSRLIYNGFWYSPEMRLLQNTMDLAQENVYGTAKLKLYKGNCVVIGRRSDRSLYQPSFATFEEDDVYRQDDATGFIRLHGLRLQIESLVRGKSR
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FETP_ECO81
Sequence: MSRTIFCTFLQREAEGQDFQLYPGELGKRIYNEISKEAWAQWQHKQTMLINEKKLNMMNAEHRKLLEQEMVNFLFEGKEVHIEGYTPEDKK
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: QUEF_RHOPS
Sequence: MSRSPRKTPKSPSLQLGQAVEWPATPDAARLDRVPNPQAGTDYLVRFTAPEFTSLCPVTGQPDFAHLVIDYAPGAWLVESKSLKLYLASFRNHGGFHEDCTVSIGKRIAAEIKPKWLRIGGYWYPRGGIPIDVFWQTGKLPKGMWVPDQGVAPYRGRG
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNC_PARL1
Sequence: MTAVRAVVTDIEGTTTPLAFVHEVLFPYARARLADFVAANADDEEVAAALGDARELGGIAGAGDAETLQLLLAWMDEDRKAGPLKLLQGLIWRHGYEEGVLKGEIYADAAAALRLWHGRGLRLFVYSSGSEAAQRLIFGHSDQGDLGPCFEGYFDTRIGAKVDSASYAAIAQSAGLPTREVLFLSDHEGEIKAAREAGMQAVTIDRTLQEEAWMEGPKAGSFSAVERALAPGKSA
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
Protein: A35_VAR67
Sequence: MDTTFVITPMGMLTITDTLYDDLDISIMDFIGPYIIGNIKTVQIDVRDIKYSDMQKCYFS
What are the official names of this protein?
Truncated protein A35 homolog.
What is the protein family that this protein belongs to?
Belongs to the chordopoxvirinae A35 protein family.
Protein: YTNM_BACSU
Sequence: MKKLIVFAFIGLLSQLIDGSLGMAYGVTSTSLLLAFGITPAVASASVHLAEVVTTAASGVSHIKFGNVDKQTVYQLVIPGSIGAFLGAAFLSQLPGDVAKPYISLFLLLLGGYVLIRFLFQYKPALEKKHVPLNRKQSIPLGVIAGFADATGGGGWGPVTTPILLSRKGLSPRKVVGTVDTSEFAIAVSATAGFLISLGWEDVNWLWVFSLMAGGIIAAPIAAWLVQKFHPQLMGVLVGGFIILVNARTLINEWIANTAVHPLIYTAIGAIWLSAVLFVLSKIGNRNIVKTAVDVHLKEK
What are the official names of this protein?
Probable membrane transporter protein YtnM.
What is the protein family that this protein belongs to?
Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EFP_PHOPR
Sequence: MASFSTNEFRSGMKIMLDNEPCVIIENEFVKPGKGQAFSRVKIRKLLSGKVLEKTFKSGESVEAADVVEVELDYLYNDGEFYHFMDNVSFEQIAADVKAVGDNAKWLVENNTCTLTLWNGNPIIVTPPNFVELEVTETDPGLKGDTQGTGGKPATLITGAVVRVPLFIQIGEVIKADTRSGEYVSRVK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.