PharMolix/UniProtQA huggingface dataset:
Protein: RL34B_SCHPO
Sequence: MAQRVTYRRRLAYNTRSNKTRIIKTPGNNIRYLHIKKLGTIPRCGDTGVPLQGIPALRPREFARLSHNQKKVQRAYGGCLSANAVKDRIVRAFLIEEQKIVKQKLKQMSQK
What are the official names of this protein?
60S ribosomal protein L34-B, 60S ribosomal protein L34-2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL34 family.
Protein: FEN1_CHICK
Sequence: MGIHGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGAEVLQNEEGETTSHLMGMFYRTIRMVENGIKPVYVFDGKPPQLKSGELAKRTERRSEAEKHLQEAQEAGEEANIEKFSKRLVKVTQQHTDECKKLLMLMGIPYVEAPGEAEASCATLVKAGKVYAAATEDMDCLTFGSPVLMRHLTASEAKKLPIQEFHLNRVLQDLGLTWEQFVDLCILLGCDYCESIRGIGPKRAVELIKQHKTIEEIIQHIDTKKYPLPENWLHKEAQKLFLEPDVINPDDVELKWTEPNEEELVQFMCGEKQFNEERIRNGVKRLSKSRQGSTQGRLDDFFKVTGSITSAKRKEPETKGSAKKKAKTNSATAKFKKGK
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: P2RY4_HUMAN
Sequence: MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL
What is the function of this protein?
Receptor for UTP and UDP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system.  Not activated by ATP or ADP.
What are the official names of this protein?
P2Y purinoceptor 4, P2Y4, P2P, Uridine nucleotide receptor, UNR.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL6_HAEIE
Sequence: MSRVAKAPVNIPAGVEVKLDGQLLTVKGKNGELSRKIHESVEVKQDNGQFTFTPREGFVEANAQSGTARALVNAMVIGVTEGFTKKLVLVGVGYRAQLKGNAIALSLGYSHPVEHTLPVGITAECPSQTEIVLKGADKQLIGQVAADIRAYRRPEPYKGKGVRYADEVVRIKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: MPTA_PYRHO
Sequence: MRELFIETQEKEPEIKIPLPRVGITNLRTIAKINWKGRVYTFIPTFEITIDLPREKKGIHMSRLVESITDAMSEAIEEEVKKIHTSLEELALAVIQRLEEKHRHKRAEVWIRTTLILEKMTPASNKLSYEPYDVEVGVIKEGDKIKKTLKVKVIGNTACPHAMANNEGKTHIQRAIGELEVTTDFNEYVTLEDMIEVVESSFSSPTYTLLKTPDENSVVRRMYENPKFVEDVAREILIKAKKKFPGKIHVKVVSNESIHKHDVIAEAWA
What is the function of this protein?
Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
What are the official names of this protein?
GTP cyclohydrolase MptA, GTP cyclohydrolase IV.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: TSPO_SHEEP
Sequence: MAPPWVPAVGFTLVPSPGGFLGTQYIRGEGFRWYASLQKPPWHPPRWILAPIWGTLYSAMGYGSYLIWKELGGFSKEAVVPLGLYAGQLALNWAWPPLFFGARQMGWAFVDLLLTGGMAAATAMAWRQVSPPAACLLYPYLAWLAFAAMLNYRMWQDNQGRRSGRRLSE
What is the function of this protein?
Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial.  It is apparently not required for steroid hormone biosynthesis.  Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme (By similarity).  Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides (PubMed:11145616).
What are the official names of this protein?
Translocator protein, Peripheral-type benzodiazepine receptor, PBR.
What is the protein family that this protein belongs to?
Belongs to the TspO/BZRP family.
Protein: ILVC_BURTA
Sequence: MKVFYDKDADLSLIKGKQVTIIGYGSQGHAHALNLKDSGVNVTVGLRRGGASWSKAENAGLAVKEVAEAVKGADVVMMLLPDEQIAAVYAQEVHANIKEGATLAFAHGFNVHYGQVIPRADLDVIMVAPKAPGHTVRGTYAQGGGVPHLIAVAQDKSGAARDIALSYAAANGGGRAGIIETNFREETETDLFGEQAVLCGGTVELIKAGFETLVEAGYAPEMAYFECLHELKLIVDLIYEGGIANMNYSISNNAEYGEYVTGPRVVTEETKKAMKQCLTDIQTGEYAKSFILENKAGAPTLQSRRRLTAEHQIEQVGSKLRAMMPWIAKNKLVDQSKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: RL44Q_CANMA
Sequence: MVNIPKTRNTYCKGKGCRKHTIHKVTQYKSGRASLFAQGKRRYDRKQSGYGGQTKQVFHKKAKTTKKIVLKLECTVCKTKKQLPLKRCKHIELGGEKKQKGQALQF
What are the official names of this protein?
60S ribosomal protein L44 Q, L41, L41 Q-type.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL42 family.
Protein: LEUC_BURO0
Sequence: MAQTLYDKLWNTHVVHTEEDGTTLLYIDRQLLHEVTSPQAFEGLKIAQRPVWRISANLAVSDHNVPTTDRSHGIADPVSKLQVDTLDSNCDAFGITQFKMNDVRQGIVHIIGPEQGATLPGMTIVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQTLLQKKSKNMLVKVEGALPRGCTAKDIVLAIIGKIGTAGGTGYAIEFGGSTIRALTMEGRMTVCNMAIEAGARAGMVAVDDTTIDYLKGRPFVPTGAEWDQAVEYWRQFKSDDGAQFDRVVELNAAEIVPQVTWGTSPEMVTSIDGRVPDPEREKDPVKRDAMERALAYMALEPNTPIESIKVDKIFIGSCTNARIEDIRAAAYVVKKLNRRVASNVRLAMVVPGSGLVKAQAEREGLDKVFTDAGFEWREPGCSMCLAMNADRLEPGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAAIEGHFVDIRQLG
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: FBID_ROSS1
Sequence: MVIHAIVPVKELHRAKQRLARVLDAHERRALSLAMLNDVLVALSYSPVSRIIVIGRDVETGHTARAHGAAFVIDQSAALNDALHQAAADIPDHAAALVAPSDLPLLGAEDVIALTCISGDKPGVAIAPAHDGGTNLLLVSPVVGWTFLFGPDSLTHHIAAARQRHLPVHLLRLPHLERDIDDIDDLIWLAQQPGDTSAQRLARMFLERKGAQLWQSSDMPPH
What is the function of this protein?
Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP.  It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
What are the official names of this protein?
Phosphoenolpyruvate guanylyltransferase, PEP guanylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CofC family.
Protein: NADE_CORGB
Sequence: MTNTQTEIINELKVSPAIDVAKEVEFRVQFLVDYLRASHAKGFVLGISGGQDSTLAGRLAQLAVERIRAEENSTDYVFYAVRLPYAIQADEDDAQVALEFIAPDKSVTVNVKDATDATEATVAAALELPELTDFNRGNIKARQRMVAQYAIAGQYGLLVIGTDHAAENVTGFFTKFGDGAADLLPLAGLSKRQGAAILEHLGAPSSTWTKIPTADLEEDRPALPDEEALGVSYADIDNYLENKPDVSEGAQQRIEHLWKVGQHKRHLPVTPQEDWWR
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: RPOZ_WOLSU
Sequence: MQRMEEIAFKALNRVNNDRYLLANILFARIDELSKGAKPLVNMDVKKHKLTDIAMTEVAEGKIALSQIDQL
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: DEOC_FRAAA
Sequence: MRRAEVARLIDHTLLAPAATDEEVLALCAEAARLGVGAVCVAPTHVYLAAASTYRSSHEAEPAFAVASVIGFPHGTHLTVIKAEEARRAVADGATEIDMVIDIANALDENWRAIETEISEVRLSVPPHVILKVILETALLPDANIIAACRAAEAGGAEFVKTSTGFHPAGGASVRAVRAMAEAVGGRLGIKASGGIRTAEKAKDMLEAGATRLGLSASADVLAGFPA
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROK_BACP2
Sequence: MKINREIPVRQRNIVLIGFMGVGKTTIGQLVAKKLYRDFIDVDQEIEKKYNMTIPEMFQQKGEAFFRQAEKDYIVDLCEHTQLKIVSLGGGAFKQEEIKRACLKHCTVLFLDLSWENWKQRLDILIENRPVLHNRTLDEMKELFEERREIYSLHNSRVETDHLEAEEVANYIVDTLKLGWDLYSK
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSH4_KLULA
Sequence: MGLIVLQDGFPNDRPIQGFPSDPVVRVPDDTIPADDAFSLMFLISLSITFGLLLLVLILISIYLTFCGGNDGDDSDDEDEDGTSVSFKFFRKRNSLLLDSSFMTPGKFDDDESLKVREAKELPKMSSFEVELYERTKEFQKMSPPMVKPLGSFLNSQDKQVIKDRGIQSYFFLPSINDNVDINGAFLPSFFVEDKLNVSFTKFNISSSAIMNYPLPMNKKDAVYFEVKVYKFKTCSNSIFSIGLMTCPYPYFRIPGTAAYSIAYESTGKLRINNAFGADTLLPKLEEGDVVGFGYRYSSGTIFITHNGKKMMDVTHKVGIDLFVGLGAMNAAYTRTYTKDGLFEDPDNVSFRQKWSELQAFNNGESSSDYIDARNVISKDLLQVHDPKEDTVSSDNIELHVNLGQLGFVFIEANVKKYAFGSVYGDIGIPPAYNGDDIKQDMLLQKGDELPPEYPDDAVDFFGDIHSPASTSEPPSATFSAGLPMDNAADTPVSTADADADADADADEEEPLISVKKPAAQTHSKKNNKKKKKKKSNRNRRG
What is the function of this protein?
Components of the endosome-vacuole trafficking pathway that regulates nutrient transport.  May be involved in processes which determine whether plasma membrane proteins are degraded or routed to the plasma membrane (By similarity).
What are the official names of this protein?
Protein SSH4.
What is the protein family that this protein belongs to?
Belongs to the SSH4 family.
What are the subcellular locations of this protein?
Vacuole membrane; Single-pass type II membrane protein. Endosome membrane; Single-pass type II membrane protein.
Protein: SCE3_YEAST
Sequence: MVQRWLYSTNAKDIAVLYFMLAIFSGMAGTAMSLIIRLELAAPGSQYLHGNSQLFNVLVVGHAVLMIFFLVMPALIGGFGNQKRYESNNNNNQVMENKEYNLKLNYDKLGPYLAGLIEGDGTITVQNSSSMKKSKYRPLIVVVFKLEDLELANYLCNLTKCGKVYKKINRNYVLWTIHDLKGVYTLLNIINGYMRTPKYEAFVRGAEFMNNYINSTTITHNKLKNMDNIKIKPLDTSDIGSNAWLAGMTDADGNFSINLMNGKNRSSRAMPYYCLELRQNYQKNSNNNNINFSYFYIMSAIATYFNVNLYSRERNLNLLVSTNNTYKTYYSYKVMVANTYKNIKVMEYFNKYSLLSSKHLDFLDWSKLVILINNEGQSMKTNGSWELGMNLRKDYNKTRTTFTWSHLKNTYLENK
What is the function of this protein?
Mitochondrial DNA endonuclease involved in intron homing.  It introduces a specific double-strand break in the DNA of the COX1 gene and thus mediates the insertion of an intron, containing its own coding sequence (group I intron), into an intronless gene.  Recognizes with high specificity and cleaves the sequence 5'-GGTTTTGGTAACTATTTATTAC-3'.
What are the official names of this protein?
Intron-encoded DNA endonuclease aI3, DNA endonuclease I-SceIII.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the LAGLIDADG endonuclease family.
What are the subcellular locations of this protein?
Mitochondrion. Membrane; Multi-pass membrane protein.
Protein: ACPS_SHEDO
Sequence: MAIIGIGTDIVEIERIREQRDRLGDKLAKRVLTLDELAIYAAVNMPERYLAKRFAAKEAAAKALGTGIGRGVSFQHIHISNDDNGAPLVNFTDGAALRLAQLGGCKGHISIADEKHYAIATVILES
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLO_ALKMQ
Sequence: MSSRIIRATAANSSIRAFVANTTNLVEKARGFHQTSPVASAALGRTLTATSMMGVMLKGEKQKITTKINGGGPLGVILVVGDSEGNVKGYVGNPQVESTNIRPGKLDVGAAVGSDGEITVIKDLGMKKPYVGTAPLVSGEIGEDFATYFLNSEQQPSAVSLGVLIDIDYRIKASGGFIIQVLPNVQEAVLAKLESRIGQLESITVMMEQGMNEVDILNHVLEGMDPKIVETYEVDFECDCNVARFEKGLISIGRQEIREMIEEDENTELVCHFCNKKYHFNKEQLQGLLDEM
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIC_ECOLC
Sequence: MSATKLTRREQRARAQHFIDTLEGTAFPNSKRIYITGTHPGVRVPMREIQLSPTLIGGSKEQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGRRVTQLHYARQGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGARLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAATQTIEMGMADMSENFRARGGEIYLRKEEA
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: RPOC2_CUSRE
Sequence: MAERINLVFHNKVLDGTAMKRLISRLIDHFGMAYTSHILDQVKTLGFQQATATSISLGIDDLLTIPSKGWLVQDAEQQSFVFEKYQHSGNVHAVEKLRQSIEIWYATSEYLRQEMHLNFRMTDPLNPVHIMSFSGARGNASQVHQLVGMRGLMSDPQGQMIDLPIQSNLREGLSLTEYIISCYGARKGVVDTAVRTSDAGYLTRRLVEVVQHIVVRRADCGTARGISVSPHNGMMPERIFIQTLIGRVLADDIYIGPRCIATRNQNIGVGLVNKLLNFRAQPISIRTPFTCRSTSWICRLCYGRSPTHGDLVELGEAVGIIAGQSIGEPGTQLTLRTFHTGGVFTGGTAEHVRAPSNGKIRFTEDLVHPTRTRHGYPAFFCSIYLYVTIQSQDILHHVKIPPKSFILVQNDQYVESEQVIAETRAGASTLNYKEKIRKHIYSDSGGEMHWSTNVYHAPEFTYGNVHLLSKTSHLWILLGEPCHSSLVSTSIHRDQDQMSAQSLSVKRRYTSKLSETNDEAKQKIASEDLIADYSDVNPSRCTDHYNLVYPAILPILDENSYFFSNCLSKRRRNQFIIPLQSIQEHKNQLMPCSSISMKIPPNANGIFCANSILAYFDDPRYRRNNSGSTKYGTLEMYSTIKKEDFIQYRGVNEFRLKSKVERFFFIPEEVHILPGSSSIMVRNQSLIGVDTQITLNLRSRVGGLVWVERKKNRIELKIFFGDIYFPGGADNLSRHSGVLIPPGTEIKTNYKESKKVKNWIYVQRITLSKKKFFFLVRPLVTYEIMDGIPLATLFPPDLLQQRENAQLRVVNYILHGNGKPIRGNYDASIQLVRTCLVFKRNQDKKSSYSEAARASVVEIRTNYLIRHFLRIDFVKAPISYIGKRYDPLGLGLLAEDWTHKNPYSKARIHQNLNQNKGTIHTFFNRNKGSQSLIILSSSNCSRMDPANGAKSNNVIQESKKEEYPMLQISNSLGPLGTYPPIANCDSFNRLLTHNQILVTNYFHLDNVKPPFQVFKFKYYFIAENLKICNYNPCSNLRLNAFYLNLNFLHPNSCAETSKIMSLGQFICQNVCIDKTRPPFKSGQVIFIQVDSVVIRLAKPYLATPGATVHGLYGETFFGGDTVVTFNYEKSRSGDITQGLPKVEQVLEVRSVDSISMNLEGRVEGWGKCITGILGIPWGFLIGAELTIVQSRISLVNKIQKVYRFQGVHIHNRHIEIIVRQITSKVLVSEDGMSNVFLPGELIGLLRAERMGRALEEPIHYRSVFLGITKASLNTQSFISEASFQETARVLSKAALGGRIDWLKGLKENVVLGGVIPAGTGFRGLVDPSKQYNKNNIPLKNNLFEGGMTDLLVHHRKLFDSFLNTLIYHHHRIDRFYNDS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta'', PEP, Plastid-encoded RNA polymerase subunit beta'', RNA polymerase subunit beta''.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
What are the subcellular locations of this protein?
Plastid.
Protein: TORD_ECOHS
Sequence: MTTLTAQQIACVYAWLAQLFSRELDDEQLTQIASAQMAEWFSLLKSEPPLAAAVNELENCIATLTVRDDARLELAADFCGLFLMTDKQAALPYASAYKQDEQEIKRLLVEAGMETSGNFNEPADHLAIYLELLSHLHFSLGEGTVPARRIDSLRQKTLTALWQWLPEFVARCRQYDSFGFYAALSQLLLVLVECDHQNR
What is the function of this protein?
Involved in the biogenesis of TorA.  Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor.
What are the official names of this protein?
Chaperone protein TorD.
What is the protein family that this protein belongs to?
Belongs to the TorD/DmsD family. TorD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_KARMG
Sequence: MINKVKGKIIQIIGPVIDVLFENVSSLPMIYDSLEVFNPKGNQIILEVQQHIGECTVRCISMDITDGLKRGQDVFSLGTTISMPIGEEINGRVFNVVGNTIDGLGDLNNSKRISIHRNPPKFEYLSTNIDILYTGIKVIDLVEPYIKGGKIGLFGGAGVGKTVLIQELINNIAKGYGGLSVFAGVGERTREGNDLLREMISSGIIKYGDSFLEDMKNGKWDISKVDKNELKNSKATFVFGQMNEPPGARARVVLSGLTLAEYYRDSFRKGRDVLFFIDNIFRFTQAGSELSALLGRMPSAVGYQPTLASEMGTMQERITSTKNGSITSIQAVYIPADDLSDPAPATTFSHLDATTVLSRKISSLGIYPAVDPLSSTSRILSIEFIGNDHYLCAQRVKQILQRYQELQDIIAILGIEELSEEDKIIVHRARRVQRFLSQPFNVAEQFTGITGKLVNIKDTIEGFNLILDGKLDNIAEVHFNLKGTISEVIDSSKKKI
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: GL1D1_PONAB
Sequence: MRLLFLAVLRPHTGNAVTAQRVRAHLEAAGHVCILKDAFDFESPSEIANLILAENCEAALALHLYRGGRLLQGHRIPFGVIFGGTDVNEDANQAEKNTVMGRVLEEARFAVAFTESMKEMAQVQWPHAKGKIYVQSQGIATTPNAAFNWNTFLQRSEINQSADNLHIFLLICGLRQVKDPLYLVDAFSEWHQEEPNVYLVILGPEVDPVFTREVKANVKRAAGVRLIGEMPQEDLHAVVKNCFAVVNSSVSEGMSAAILEAMDLEVPVLARNIPGNAAMVKHEVTGLLFSNPQEFVHLAKRLVSDPALEKEIVVNGKEYVRMYHSWQVERDTYQQLIRKLEGSTED
What are the official names of this protein?
Glycosyltransferase 1 domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RT48_ECOLX
Sequence: MGRPYVTLNLNGMFMDKFKPYSKSNAPITTLEKLSKALSISVEELKAIAELPLDEKYTLKEIPKIDGSKRIVYSLHPKMRLLQSRINKRIFKELVVFPSFLFGSVPSKNDVLNSNVKRDYVSCAKAHCGAKTVLKVDISNFFDNIHRDLVRSVFEEILHIKDEALEYLVDICTKDDFVVQGALTSSYIATLCLFAVEGDVVRRAQRKGLVYTRLVDDITVSSKISNYDFSQMQSHIERMLSEHDLPINKRKTKIFHCSSEPIKVHGLRVDYDSPRLPSDEVKRIRASIHNLKLLAAKNNTKTSVAYRKEFNRCMGRVNKLGRVAHEKYESFKKQLQAIKPMPSKRDVAVIDAAIKSLELSYSKGNQNKHWYKRKYDLTRYKMIILTRSESFKEKLECFKSRLASLKPL
What is the function of this protein?
Reverse transcriptase (RT) component of antiviral defense system retron Ec48, composed of a non-coding RNA (ncRNA), this reverse transcriptase (RT) and the following membrane protein.  Expression of this retron confers protection against bacteriophages lambda, T2, T4, T5 and T7.  At multiplicity of infection (MOI) of 0. 02 cultures grow normally when infected with lambda without collapsing, at MOI 2 cultures enter growth stasis.  At MOI 3 cell membranes are permeabilized within 15 minutes of infection but do not lyse, suggesting the phage are not able to finish a replication cycle.  Antiviral defense is suppressed by mutations that knockout the lambda gam expression or phage T7 gp5. 9 expression; both viral genes inhibit host RecBCD (PubMed:33157039).  The Ec48 retron may sense the integrity of the RecBCD enzyme; when RecBCD is perturbed by viral proteins the Ec48 effector (the membrane protein) is activated, leading to abortive infection and bacterial growth arrest (Probable).  Responsible for synthesis of msDNA-Ec48 (a branched molecule with RNA linked by a 2',5'-phosphodiester bond to ssDNA).  The retron transcript serves as primer (from a conserved internal G residue) and template for the reaction, and codes for the RT (PubMed:8878541, PubMed:9401048).
What are the official names of this protein?
Retron Ec48 reverse transcriptase, RT-Ec48, ECOR-58 reverse transcriptase.
What is the protein family that this protein belongs to?
Belongs to the bacterial reverse transcriptase family.
Protein: PSB1_SULIN
Sequence: MEELPATAIGLKVNDGIVLASERRLSYGGYVLSKQAKKVHKIGKFLMAGAGIYGDLQTLTRIMNVEIKYYEISTGKPISVHAAAKLLSVILYQYKVMPFISEILFGGVDEKGPQLYVLDPIGSLIEDNYAAVGSGARIAIGVLESEYDPNMNLDIAAQLITKAIKASIERDITSGDGIDLAIMDKKGNYENKFIPY
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta 1, 20S proteasome beta subunit 1, Proteasome core protein PsmB 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AP3_VITVI
Sequence: MARGKIEIKRIENSTNRQVTYSKRRNGIFKKASELTVLCDAKVSIIMLSSTGKLHEYISPSTTTKQIFDQYQNTLGVDLWSYHYERMQENLKKLKDVNKNLRKEIRQRMGEHLSDLSVEELRDLEQEMESSLKMVRDRKYQVINNQIETFKKKVRNVEQIHKNLLHEFDARDRDQHYGLVDNGGDYESVLGFSNGSSPVFALSLQPNPPNDLHSGVGSDLTFTLLE
What is the function of this protein?
Probable transcription factor involved in flower development.
What are the official names of this protein?
Agamous-like MADS-box protein AP3, VvAP3.1, VviAP3a.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLO2_HAES1
Sequence: MLIPIPALNDNYIWVYKRENLSVIVIDIPEIAALSQFIQAQNLVIGALLITHNHRDHIGALAEFKQFYPHVHIYGPAECADQGVTQVIDAGRLIIDEYHIDVLPTGGHTAQHLSFLIDGHLFCGDTLFSAGCGRVFTGDYSQMFTSLQLLKSLPDETIVCPAHEYTLGNLAFALTTGKNKSAVQKQLEKVKKLRAENKPSLPTTLALEKQINPFLQVESLDEFIELRKAKDVF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.