PharMolix/UniProtQA huggingface dataset:
Protein: STR1_MEDTR
Sequence: MARLERDGTNKSLESLMDSHKPGGTTTNLNQLRTQKSIPGYGLEFTNLSYSIIKKQKKDGVWINKETYLLHDISGQAIKGEIMAIMGPSGAGKSTFLDALAGRIAKGSLQGSVRIDGKPVTTSYMKMVSSYVMQDDQLFPMLTVFETFMFAAEVRLPPSISRDEKKKRVHELLNKLGLQSATHTYIGDEGRRGVSGGERRRVSIGIEIIHKPSLLFLDEPTSGLDSTSAYSVVEKIKDIAQGGSIVLMTIHQPSFRIQMLLDKITILARGRLIYMGRPDALHTHLSGFGRPVPDGENNIEYLLDVITEYDQATVGLDPLVQYQHDGHKPDPAAMTPVPKPPRTPYRRNTPASKHMISLRSQGFTAGTPQPDSSQFGLDDDDNDDDENFDNSLERRSVQTSRNIVTSGVYPRLASQFYQDFSAKDFSVWLYNGVVGTPRRPPSWTPARTPGWTPGKTPLSGPRSFVSNQHSASYQDPYYIQKTNTVVGQSMDYSATSYAPSYEEFEIEEVLDEPDLGPKYANPWLREVAVLSWRTVLNVIRTPELFASREIVLTVMALVLSTIFKNLGDTTFIDINRLLNFYIFAVCLVFFSSNDAVPSFIMERFIFIRETSHNAYRASSYVISSLIVYLPFFAVQGLTFAVITKLMLHLKSNLFNFWMILFASLITTNAYVMLVSALVPSYITGYAVVIATTALFFLTCGFFLKRTQIPAYWKWLHYISAIKYPFEGLLINEFKNNRGCYSGNKADLSPGPLGDVKPSKHHNASLPLNCLLGEDVLSTMDITMESLWYDILILLAWGVLYRFFFYLVLRFYSKNERK
What is the function of this protein?
Together with STR2, required for arbuscule development in arbuscular mycorrhizal (AM) symbiosis.
What are the official names of this protein?
ABC transporter G family member STR, Protein STUNTED ARBUSCULE.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. Stunted arbuscule (STR) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Located in the peri- arbuscular membrane of arbuscular mycorrhiza (AM).
Protein: SPH28_ARATH
Sequence: MINSSKINLYSYVCSIFIMSIVVISLICSEALQIQQAKEPFRGHLTRVTIQNYNDYLLAIHCKSRDDDLGFHILAKGELFGWKFHVNFRYSTLCFCGFSQRQINKGVFIIYVASRDFYRCANCTWKAEKDGFHGYGDIPTRGYLFYNWLN
What are the official names of this protein?
S-protein homolog 28.
What is the protein family that this protein belongs to?
Belongs to the plant self-incompatibility (S1) protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: ESC8_YEAST
Sequence: MTEIIDLDLVDDFIKKPMVKQQKNQSSKPRVKRRGQLTFDDFRNIKIVEEPVVLSHNSSIDESLDAATQNTKKREKYEGTCDEEMKTKEMEANMASKYSNIKTHSNDTNKVESISEHTTSNNRPLNTLNWSPNIPLRYSDFAKFMSDETVTESNWAPPLCTPLPYAGDVMKILSFIVKFKWVFSDDLLNLSFQDVEIGLELKVAGHSAKNIRICQDKMNLLFCSLLRLLFCSEKRADNQTHRNFTLKRFLSLKNPYGKLVGKLRSLIQEWGLPKEWRGNSDILSTLNFNGGGLLTMEPLDRIILLRCMIDWNCSYSALFHNEIQRLTHLKGDTGFNHQTFHASRFAMCGANNILDSCEVLCSLMSQKLENRKKRKPSDKGKLSKINSQMKFLKGVRKSLSEKVTTDRLRAAVKINEEWGEYFANEFTHTPIDDPTVDEIYKLRTSEFMIARIPRVGDFYLPPFWIGNECSSVNTSYSFNDMSTYLNYFVKFKEEGTKILPAKTAQNENKCQLKLIYRNTPACIRNLQFNDVHFAEVPHWFEVAGDSNSLSNFIEYLESLSSLTENDTDDTKKGIDNLIEFLKIFSIFINETIQRITAAPTGSTEGRHLRTSSQRRTTVHYSSDVNGDVSEESENEVDIDVSDDYDSEYLSEENTLTRKGEDRTDKSFGKRELHNGAKDCDRNCDDIEIFSEPVRQLQDNSREKRSLRRNARKGL
What is the function of this protein?
Involved in HMR and telomere silencing via the recruitment or stabilizing of the SIR (silent information regulators) complex.
What are the official names of this protein?
Protein ESC8, Establishes silent chromatin protein 8.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GL24_ORYSJ
Sequence: MAHRRRCLLLLLAVLLPAMAARGDPDAVQDFCVPDAGRGRPVELAMLPAYPCRSPANLTAGDFAFSGVRAAGNFSPETGFAGVSVTPAQFPGLHTLGMSFARADLSAAGGVNPPHYHPRATETALVLAGRVYAGFVDSGGRLFAKVLEQGEVMVFPRAMVHFQLNVGDTPATVYGAFNSENPGIVRIPATVFGSGIREAVLERAFGLTPAELRRLEKRFGPPKKAEMED
What is the function of this protein?
May play a role in plant defense.  Probably has no oxalate oxidase activity even if the active site is conserved.
What are the official names of this protein?
Germin-like protein 2-4.
What is the protein family that this protein belongs to?
Belongs to the germin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: ICID_SOLTU
Sequence: MESKFAHIIVFFLLATSFETLLARKESDGPEVIELQKEFECNGKQRWPELIGVPTKLAKGIIEKENSLITNVQILLNGSPVTMDYRCNRVRLFDNILGDVVQIPRVA
What is the function of this protein?
Inhibits both chymotrypsin and trypsin.
What are the official names of this protein?
Wound-induced proteinase inhibitor 1, Chymotrypsin inhibitor I, D subunit, Wound-induced proteinase inhibitor I.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I13 (potato type I serine protease inhibitor) family.
Protein: ASSY_SACD2
Sequence: MSTNSSIKKVVLAYSGGLDTSVIVKWLQETYNCEVVTFTADIGQGEEVEPARAKAEALGVKEIYIDDLREEFVRDYVFPMFRANTIYEGEYLLGTSIARPLIAKRLIEIANETGADAISHGATGKGNDQVRFELGAYALKPGIHVIAPWRDWDLTSRETLMDYCAKHNIPVDYTKAKKKSPYSMDANLLHISYEGGILEDPWAEAEEDMWRWSVSPEAAPDQPEYLELTFKHGDIVAIDGVEMSPATVLETLNKRGGAHGVGRLDIVENRYVGMKSRGCYETPGGTIILRAHRAIESITLDREVAHLKDSLMPKYAEMIYNGYWWSPERQMLQTAIDNSQGPVNGDVRVKLYKGSVTVVGRRSNDSLFDEKIATFEDDAGAYNQKDAEGFIKLNALRMRIAAQKGRKLL
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TATA_CUPMC
Sequence: MGSFSIWHWLIVLVIVMLVFGTKKLRNIGQDLGGAVKGFKDGMKEGNTDEPATPTPAKELRDSTTIDVEAKEKSRQQ
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: COBU_ECO57
Sequence: MMILVTGGARSGKSRHAEALIGDSSQVLYIATSQILDDEMAARIEHHRQGRPEHWRTVERWQHLDELIHADINPNEVVLLECVTTMVTNLLFDYGGDKDPDEWDYQAMEQAINAEIQSLIAACQRCPAKVVLVTNEVGMGIVPESRLARHFRDIAGRVNQQLAAAANEVWLVVSGIGVKIK
What is the function of this protein?
Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.
What are the official names of this protein?
Bifunctional adenosylcobalamin biosynthesis protein CobU, Adenosylcobinamide kinase, Adenosylcobinamide-phosphate guanylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobU/CobP family.
Protein: TIG_BARBK
Sequence: MQVTETLNEGLKREIQVMVPMKDLEAKLNERLDDTKGKIKLNGFRPGKVPSSYLRKMYGKSFMAEVLNEIINDAPRSILVDRNERSAVQPQIDINEDQKVLDGEADFIFNLKYEVLPEFEIKDFKDIEITREIADVSEQEIDEEVKKILSSTRSYSEGDAPSEEGDRVTIDYLGKIDDVPFDGGTGHDVQLVLGSNQFIPGFEEQLVGVKAGDTKAISVKFPDNYGVAHLAGKDAVFNITVKTVSKPDELKIDDEAAKKLGLESLDRLREVVQGQIENQYGLMTRQKIKRQILDSLDADYNFEIPERLVEIEFNNIWAQVNSDLQKSGRSFEDENTTEEKAREEYHMLAQRRVRLGLVLSEIGMKANIQVSESELQTAIFEQVRQYPGQEKEIMNFFRRTPEAIANLRAPIFEEKVIDYLLTHIKIKDKKVTVEELMKEFDESDAIEKSLVKKKTASDNKKSNEIKKKSTMKKV
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: DUT_XANCB
Sequence: MTQSLQVKLLDPRFGDLWPLPAYATEASAGMDLRAALEAPMTLEPGDAALIPSGIAIHLDDPQVCAVILPRSGLGHRHGIVLGNGTGLIDADYQGPLLISTWNRGREAFTIEPGDRIAQLVILPIVRVSLQVVDTFVDSARGAGGFGHTGVR
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: RL28_THEP3
Sequence: MLKCDICGKGPLAGYQYSHSHRKSIRKWKPNIKKVRAIVDDTPVRLHVCTKCLKAGKVQRAL
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: MPPE1_DANRE
Sequence: MTLVFGSSCRLAVTLIFAFVSVFVFCEYVIYYLVILRCSWPLLEIEDSHSPLRALFLSDTHLLGAIRGHWLDKLRREWQMERAFQTSMWLLNPEVVFILGDVFDEGKWSTSQDWEDDVRRFKRIFRHPVDTKLVVLVGNHDIGFHHEMTKQKLERFEQVFNVTSARILTIKGVNFLLVNSVALHGDHCPICQHVEEELQKLSHALNCSIQGAQHNGQCKNAARFAPAAPVLLQHYPLYRVSDAMCTGVDTAPLDEQYLLFQERYDVISKNASKKLLWWFKPRLILSGHTHNGCEVLHEKLYPEISVPSFSWRNRNNPSFVLGTFSQSEFQLSKCFLPEERTVLVVYCSSCLIIALITLIHLKMFRNSLQFTNNLIGKHKTL
What is the function of this protein?
Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi.  Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins (By similarity).
What are the official names of this protein?
Metallophosphoesterase 1, Post-GPI attachment to proteins factor 5.
What is the protein family that this protein belongs to?
Belongs to the metallophosphoesterase superfamily. MPPE1 family.
What are the subcellular locations of this protein?
Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi- pass membrane protein. Note=Also localizes to endoplasmic reticulum exit site.
Protein: ATG4B_CHICK
Sequence: MDAATLTYDTLRFEYEDFPETKEPVWILGRKYSVFTEKEEILLDVTSRLWFTYRKNFPAIGGTGPTSDTGWGCMLRCGQMIFAQALVCRHLGRDWRWIKGKRQTDNYFSVLNAFIDKKDSYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLATFDTWSSLAVHIAMDNTVVMEEIRRLCQSNFSCAGAAACPAVEADVLYNGYPEEAGVRDKLSLWKPLVLLIPLRLGLTEINEAYIETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPSDSGCLPDESFHCQHPPCRMSIAELDPSIAVGFFCHTEEDFNDWCHQIKKLSLVRGALPMFELVERQPSHFSNPDVLNLTPDSSDADRLERFFDSEDEDFEILSL
What is the function of this protein?
Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins (PubMed:15140988).  Required for canonical autophagy (macroautophagy), non-canonical autophagy as well as for mitophagy.  The protease activity is required for proteolytic activation of ATG8 family proteins: cleaves the C-terminal amino acid of ATG8 proteins to reveal a C-terminal glycine.  Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy.  Protease activity is also required to counteract formation of high-molecular weight conjugates of ATG8 proteins (ATG8ylation): acts as a deubiquitinating-like enzyme that removes ATG8 conjugated to other proteins, such as ATG3.  In addition to the protease activity, also mediates delipidation of ATG8 family proteins.  Catalyzes delipidation of PE-conjugated forms of ATG8 proteins during macroautophagy.  Also involved in non-canonical autophagy, a parallel pathway involving conjugation of ATG8 proteins to single membranes at endolysosomal compartments, by catalyzing delipidation of ATG8 proteins conjugated to phosphatidylserine (PS).
What are the official names of this protein?
Cysteine protease ATG4B, Autophagy-related cysteine endopeptidase 2B, Autophagin-2B, cAut2B, Autophagy-related protein 4 homolog B.
What is the protein family that this protein belongs to?
Belongs to the peptidase C54 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytosol. Cytoplasmic vesicle, autophagosome. Endoplasmic reticulum. Mitochondrion. Note=Mainly localizes to the cytoplasm, including cytosol.
Protein: COAA_ECOSM
Sequence: MSIKEQTLMTPYLQFDRNQWAALRDSVPMTLSEDEIARLKGINEDLSLEEVAEIYLPLSRLLNFYISSNLRRQAVLEQFLGTNGQRIPYIISIAGSVAVGKSTTARVLQALLSRWPEHRRVELITTDGFLHPNQVLKERGLMKKKGFPESYDMHRLVKFVSDLKSGVPNVTAPVYSHLIYDVIPDGDKTVVQPDILILEGLNVLQSGMDYPHDPHHVFVSDFVDFSIYVDAPEDLLQTWYINRFLKFREGAFTDPDSYFHNYAKLTKEEAINTAMTLWKEINWLNLKQNILPTRERASLILTKSANHAVEEVRLRK
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TLP_GEOTN
Sequence: MPRPKPDDRSDNVEKLQDMVQNTIENIEKAEETMQFASPEERERIREKNRRREEAIAAMRAEIKDEAAAREHGYQ
What are the official names of this protein?
Small, acid-soluble spore protein Tlp.
What is the protein family that this protein belongs to?
Belongs to the Tlp family.
What are the subcellular locations of this protein?
Spore core.
Protein: ALG3_SCHPO
Sequence: MSSVETRNSFNPFRVLFDLGSYGWLHPSRLLLLEIPFVFAIISKVPYTEIDWIAYMEQVNSFLLGERDYKSLVGCTGPLVYPGGHVFLYTLLYYLTDGGTNIVRAQYIFAFVYWITTAIVGYLFKIVRAPFYIYVLLILSKRLHSIFILRLFNDGFNSLFSSLFILSSCKKKWVRASILLSVACSVKMSSLLYVPAYLVLLLQILGPKKTWMHIFVIIIVQILFSIPFLAYFWSYWTQAFDFGRAFDYKWTVNWRFIPRSIFESTSFSTSILFLHVALLVAFTCKHWNKLSRATPFAMVNSMLTLKPLPKLQLATPNFIFTALATSNLIGILCARSLHYQFYAWFAWYSPYLCYQASFPAPIVIGLWMLQEYAWNVFPSTKLSSLIAVCVPLITILKLYTSDYRKP
What is the function of this protein?
Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-Dol.
What are the official names of this protein?
Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase, Asparagine-linked glycosylation protein 3, Dol-P-Man-dependent alpha(1-3)-mannosyltransferase, Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase, Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 58 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: COWN_ALLVD
Sequence: MSQAAVKIDRYITFEGIECDEQARRVLDCIRDCIEAPEASSWSAYFERKLDEITRMGQDELFVVGSQVNYIRALFEHHGHREGLDLLDRIEDECC
What is the function of this protein?
Is required to sustain N(2)-dependent growth in the presence of low levels of carbon monoxide (CO).  Probably acts by protecting the N(2) fixation ability of the nitrogenase complex, which is inactivated in the presence of CO.
What are the official names of this protein?
N(2)-fixation sustaining protein CowN, CO weal-nitrogenase.
What is the protein family that this protein belongs to?
Belongs to the CowN family.
Protein: PETD_PROM5
Sequence: MSTLKKPDLSDPKLRAKLAKGMGHNYYGEPAWPNDLLYIFPVVILGTIACVVGLAVLDPAMLGDKANPFATPLEILPEWYLYPVFQILRVVPNKLLGIALQTLIPLGLMILPFIENVNKFSNPFRRPVAMVVFLFGTFLTIYLGIGACLPIDKSLTLGLF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 4, 17 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetD subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: NU2C2_IPOPU
Sequence: MSWHVQNENFILDSTRIFMKAFHLLLFDGSLIFPECILIFGLILLLMIDSTSDQKERPWLYFISSTSLVMSITALLFRWREEPMISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDFITIFVAPECFSLCSYLLSGYTKKDVRSNEATMKYLLMGGASSSILVHGFSWLYGLSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGIGFKLSPAPSHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNDGYASMITYMLFYISMNLGAFACIVLFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGLPPLAGFFGKLYLFWCGWQAGLYFLVFIGLLTSVVSIYYYLKIIKLLMTGRNQAITPHVRNYRRSPSNNSIELSMIVCVIASTIPGISMNPIIAIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 B, chloroplastic, NAD(P)H dehydrogenase, subunit 2 B, NADH-plastoquinone oxidoreductase subunit 2 B.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PDXS_THEAC
Sequence: MTLDLNKLRFGSELIKRGFSAMTKGGVIMDVTTADQAKIAEAAGAVAVMALERVPADIRAAGGVARMADPMKIKEIMDAVSIPVMAKVRIGHISEAYVLEKIGVDMLDESEVLTPADPFFHLYKKNLTVPVVSGARNLPEAVRRIFEGAAMIRTKGEAGTGNIIEAVRHIRKVNEEISVLKRMSDEQLRAVASNISASYFVLREEASKDLMGVEGKLSYDSAYAGMGRSRIEREILAILRQIRRMGRLPVVNFAAGGVATPADGALMMELGADGVFVGSGIFKSPNPEKMARSIVEAVENYRDYDVVEKASEGLQGMPGVDIESIPKDMRLQERGW
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: RRP41_PYRAE
Sequence: MKRPPVPLLQNGVRADGRTPDQMREVKIAVGVVSNADGSAMVSYGATTAVAAVYGPREMHPRHLSLPDRGVMRVRYHMAPFSTKDERKSPTPSRREIEISKILREALEPAIVLEQYPRSRIDVFVEILQADGSTRVASLTAASLALADAGIYMRDLVVGVSVGLVDGTVVLDLNGLEDQYGEGDLPLGYMPNLKRFTLLQLDGAWTRDMFLQALNLAVRGAEYVYQIARDALKNKYMSIAEEIYGR
What is the function of this protein?
Catalytic component of the exosome, which is a complex involved in RNA degradation.  Has 3'->5' exoribonuclease activity.  Can also synthesize heteromeric RNA-tails.
What are the official names of this protein?
Exosome complex component Rrp41.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family. Rrp41 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QTRT2_DROGR
Sequence: MKFVIKSISKNSGRLGQLRIGKESNELQTPLLMQTTKGGSIPYLSGDVFDSVCKGQQQQQLLQLTLSTMDQMAESLVQWNRSLSEYVGLPGHATVLLLRDPCETTPAGGNDRDVVPLFTRRGKESLTATRYLELVSSFAPDVYQGLCDADTNPDSTKKRVQKSVDRTERFMEQCYERRVENSTLLAPIVGGYNTFARTQSIKHARQQPAGSYGGYILEGFHSNGLAATELKATQLLPIVEHCVQQLEEEQPRLMPGAYTPLLMLELIRQGIDIFDTSYAYCAAVNYKALSFSYKLDEIRPDDEHTPLLDMTAEEYKEQFKPLLSGCTCLACEKHTRAYHHHLYKTHELLGPILLMIHNLHHLMGFFDVIRASIGTDQLPALLEHLRMQNTSTEINYRIEPNNKIVTKAAMGKGFIAPAV
What is the function of this protein?
Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase accessory subunit 2, Queuine tRNA-ribosyltransferase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLME_BLOFL
Sequence: MFIKVNTKYFIDQYALQAQNQKLRSRSWFKLQSIDRLDKLLKQGMTVIDLGSTPGGWSSYVIKQISNLGTIVSCDILPMKKIAGVKFLQGDCSNINFLNEIDLKIKHKRAQVVLSDMSPNTTGISTVDVCKSIYLGKIALNMCCRFLAPGGSFLVKIFQGDGFDQYLYNLKCLFHKVKVRKPSSSRSHSREVYIVSKDFKYKRINI
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS_LACCB
Sequence: MPQKTSETPMMQQYNEIKAQYPDAFLFYRIGDFYELFNDDAIKGAQLLELTLTARNKSADDPIPMAGVPHHAVQSYVDILIDHGYKVAICEQMEDPKKAVGMVKRAVIQLVTPGTNVDIKAGAAKSNNYITAVMPHAAGYAFAYADVSTGELKVTDLKSKFALQNELSALATKEIVVPEELTDDDAGMLKQGERLLSVQPDAEPTSEGSYVSQELTDPAEAAVVQMLMAYLLNTQKRSLAHIQKAVAYQPSAYLEMDQDARSNLDILQNSRTGRKGDTLLSLLDSTKTAMGGRLLKQWLDRPLLDIDAISVRQNQVQDLLDHFFERSELQERLTKVYDLERLAGRVAFGTVNGRDLIQLQTSLDQIPAIQDVLGKLDDGSFKALRSKMDPVSDVAGLIRRAIEPEPPISVTDGGLILRGYNQKLDSYRDAMKNSKQWIAELEASERKATGIHTLKIRYNKVFGYFIEVTKSNLDKIPEGRYERKQTLTNAERFITPELKEKETLILEAQESSTALEYDLFQDIRDKVKAQIKRLQALAAQISSLDVLQSFATVAENSHYVRPTMHAGTHDINVKGGRHPVVEHVLGRDSYIPNDVIMNHDTDMLLITGPNMSGKSTYMRQLALIVIMAQAGSFVPADVADLPIFDQIFTRIGAADDLANGESTFMVEMLEANAALSHATASSLILFDEIGRGTATYDGMALAQAIIEFLHDHVHAKTLFSTHYHELTSLSDSLAKLKNVHVGAVEEHGNLVFLHKMMPGPADKSYGIHVAKLAGLPADLLARADTILKQLEADAPNKTAPAPAPQVEEQQLSLFEEPKPTPKNSPILTKLAKFDLMAATPMDAMNFIFDLQKHLKKK
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: ORF1_USTMA
Sequence: MPSRIPSSNDPVLPGRELWGTERFWHFAHHEHQGAFDMVSIFVVDVGSRHLSIEDWRKAWSKLYRTFAVLSQKISDDSGEGKIVDGALRAEESFFTGPILQDDQDRIDYSLQQRRFDCLSLTVFATSGTEHESFHLAISNPHALGDAKGIFAIGKALIQGVLSQTQAELQSPTSPPPQPSLKAFTTSHNQDLGLKAMFEVARTGSSIGFPILPKETSAELEPASREWRRVFTFSPAQTETLVQLCKAKALTVSAWLQATILHALIDTLVDDKGDEKAEQTFTVAAMPFHSPLSVSGATSTIFAPISIRVGSKAELNDIAEAVAESFGLARRFAEDVQDDYVKTLLKLFGSVRLETSVPTFSSLGRLDTVTGLKRYHVVARNNLPTTGIHAWTLNDQLNLTLSWAPARFRRDHIEKFWSTWIGTIKEVVA
What is the function of this protein?
Probable alcohol acetyltransferase; part of the gene cluster that mediates the biosynthesis of the glycolipid biosurfactant ustilagic acid (UA) (PubMed:15932999, PubMed:17850255).  UA is a secreted cellobiose glycolipid that is toxic for many microorganisms and confers biocontrol activity to U. maydis (PubMed:15932999, PubMed:17850255).  UA consists of 15,16-dihydroxypalmitic or 2,15,16-trihydroxypalmitic acid, which is O-glycosidically linked to cellobiose at its terminal hydroxyl group (PubMed:17850255).  In addition, the cellobiose moiety is acetylated and acylated with a short-chain hydroxy fatty acid (PubMed:17850255).  UA biosynthesis starts with omega-hydroxylation of palmitic acid catalyzed by the cytochrome P450 monooxygenase cyp1 (PubMed:17850255).  Terminal hydroxylation of palmitic acid precedes subterminal hydroxylation catalyzed by the cytochrome P450 monooxygenase cyp2 (PubMed:17850255).  Sequential glucosylation of the hydroxy fatty acid is probably catalyzed by the glycosyltransferase ugt1 (Probable).  The cellobiose lipid is further decorated by acetylation of the proximal glucose residue and by acylation with a short-chain beta-hydroxy fatty acid at the distal glucose residue (Probable).  The acyltransferase uat1 may be a good candidate for catalyzing either acetylation or acylation of the cellobiose lipid (Probable).  The fatty acid synthase fas2 may be involved in synthesis of the carbon backbone of the short-chain beta-hydroxy fatty acid esterified to the cellobiose disaccharide (Probable).  The secreted UA consists of a mixture of both alpha-hydroxylated and non-hydroxylated glycolipids; therefore, alpha-hydroxylation of the long-chain fatty, catalyzed by the fatty acid hydroxylase ahd1, occurs late in UA biosynthesis and may be the last step before secretion (PubMed:17850255).
What are the official names of this protein?
Probable alcohol acetyltransferase orf1, Ustilagic acid biosynthesis cluster protein orf1.
What is the protein family that this protein belongs to?
Belongs to the alcohol acetyltransferase FCK4 family.