PharMolix/UniProtQA huggingface dataset:
Protein: CEAM6_HUMAN
Sequence: MGPPSAPPCRLHVPWKEVLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLAHNLPQNRIGYSWYKGERVDGNSLIVGYVIGTQQATPGPAYSGRETIYPNASLLIQNVTQNDTGFYTLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPEVQNTTYLWWVNGQSLPVSPRLQLSNGNMTLTLLSVKRNDAGSYECEIQNPASANRSDPVTLNVLYGPDVPTISPSKANYRPGENLNLSCHAASNPPAQYSWFINGTFQQSTQELFIPNITVNNSGSYMCQAHNSATGLNRTTVTMITVSGSAPVLSAVATVGITIGVLARVALI
What is the function of this protein?
Cell surface glycoprotein that plays a role in cell adhesion and tumor progression (PubMed:2803308, PubMed:2022629, PubMed:1378450, PubMed:8776764, PubMed:11590190, PubMed:10910050, PubMed:14724575, PubMed:16204051).  Intercellular adhesion occurs in a calcium- and fibronectin-independent manner (PubMed:2022629, PubMed:16204051).  Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM5 and CEACAM8 (PubMed:2803308, PubMed:2022629, PubMed:8776764, PubMed:11590190, PubMed:16204051).  Heterophilic interaction with CEACAM8 occurs in activated neutrophils (PubMed:8776764).  Plays a role in neutrophil adhesion to cytokine-activated endothelial cells (PubMed:1378450).  Plays a role as an oncogene by promoting tumor progression; positively regulates cell migration, cell adhesion to endothelial cells and cell invasion (PubMed:16204051).  Also involved in the metastatic cascade process by inducing gain resistance to anoikis of pancreatic adenocarcinoma and colorectal carcinoma cells (PubMed:10910050, PubMed:14724575).
What are the official names of this protein?
Carcinoembryonic antigen-related cell adhesion molecule 6, Non-specific crossreacting antigen, Normal cross-reacting antigen.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. CEA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Apical cell membrane. Cell surface. Note=Localized to the apical glycocalyx surface.
Protein: PTH_SALPB
Sequence: MAIKLIVGLANPGAEYAATRHNAGAWYIDLLAERLRAPLREEPKFFGYTSRITLEGEDVRLLVPTTFMNLSGKAVGAMASFYRIQPDEILVAHDELDLPPGVAKFKLGGGHGGHNGLKDIISKLGNNPNFHRLRVGIGHPGDKNKVVGFVLGKPPVSEQKLIDEAIDEAARCTELWFKEGLAKATSRLHTFKAQ
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG1_PSEPK
Sequence: MARTTAINRYRNIGICAHVDAGKTTTTERILFYTGLSHKMGEVHDGAATTDWMVQEQERGITITSAAVTTFWKGSRGQYDNYRVNVIDTPGHVDFTIEVERSLRVLDGAVVVFCGTSGVEPQSETVWRQANKYGVPRVVYVNKMDRAGANFLRVVGQIKNRLGHTPVPVQLAIGSEDNFQGQVDLIKMKAIYWNDDDKGTTYREEEIPADMVELANEWRNNMVEAAAEATEELMNKYLEEGELSVEEIKAGLRARTLASEIVPAVCGSSFKNKGVPLVLDAVIDFLPAPTEIPAIKGIHPDLIDVPKDEVKPEQFDERHADDDEPFSALAFKIATDPFVGTLTFVRVYSGFLTSGDSVINSVKGKKERVGRMVQMHANQREEIKEVRAGDIAALIGMKDVTTGDTLCNADKPIILERMDFPEPVISLSVEPKTKQDQEKMGIALGKLAQEDPSFRVKTDEETGQTIISGMGELHLDILVDRMKREFNVEANIGKPQVSYREKITKSNVEIEGKFVRQSGGRGQFGHCWVRFSEPDVDDKGNITEGLVFSNEVVGGVIPKEYIPAIQKGIEEQMKNGVVAGYPLIGLKAAVFDGSYHDVDSNEMAFKIAASMATKQLAQKGGGVVLEPIMKVEVVTPEDYLGDVMGDLNRRRGLVQGMDESVSGRVVRAEVPLGEMFGYATDVRSMSQGRASYSMEFSKYAEAPSNIVEALVKKQG
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G 1, EF-G 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ABRX1_BOVIN
Sequence: MEGESTTAVLSGFVLGALAFQHLNTDSDTEGFLLGEVKGEAKNSITDSQMDDVEVIYTIDIQKYISCYQLFSFYNSSGEVNEQALKKILSNVKKDVVGWYKLRRHSDQIMTFRERLLHRNLQQHLSSQELVFLLLTPSIITESCSTHRLEHALYKPQKGLFHRIPLVVANLGMSEQLGYKTTSGSCTSAGFSRAVKTHSSEFFKEDGSLKEVQKINEMYTSLQDELKSICEKVEHSERAVEKLLNDVNRLKGEIKKRKQAQMQATREKNVQKDPQENILLCQALRTFFPDCELLHSCVISLKNRRISGSSCTTTHPLSGVDNLTLMVEYTDFPEASPARSALLVTKRKASDTDDGWQFKKSRLGGIQNRPSKTDTNSSNQEQASTVSSPETDEEIERMKGSGEYPQSPTF
What is the function of this protein?
Involved in DNA damage response and double-strand break (DSB) repair.  Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1.  The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs.  This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX.
What are the official names of this protein?
BRCA1-A complex subunit Abraxas 1, Coiled-coil domain-containing protein 98, Protein FAM175A.
What is the protein family that this protein belongs to?
Belongs to the FAM175 family. Abraxas subfamily.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes at sites of DNA damage at double-strand breaks (DSBs).
Protein: ENO_PYRHO
Sequence: MENPYEITAIVAREILDSRGNPTVEVDVHTPIAMGRAAVPSGASTGTHEAVELRDGGKRYHGKGVRRAVENVNKIIAPELIGMDVRWQREIDKLLIELDGTENKSNLGANAILAVSLAVAKAAANSLELPLYQYLGGVNAYVLPVPLSNVINGGVHAGNELDFQEFMIMPIGASSFREAIRWVSETYHVLKRVIMGKYGKNAVNVGDEGGFAPPMKEVTEPLDALIKAIEEAGYKPGDEIALAIDAASSEFFKDGKYIVGGKEYTREELLDLYKELVSTYPIVSIEDPFHEEDWEGFVMITNELGKKIQIVGDDLFVTNPRRLKKGIELGAANALLLKVNQIGTLTEAMDAAYTAFRAGYSVIVSHRSGETEDTTIADLAVALNAGQIKTGAPARSDRNAKYNQLIRIEEELEGIAVYAGKNFRKVFF
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: LGT_POLNS
Sequence: MLIHPQFDPAAIRIGSFAIHWYGLMYLMAFVQFLLLGRLRIRAPRYQALGWTYKYLEDLLFAGVLGVVLGGRLGYTLFYMPGFYLANPLGIFKIWEGGMSFHGGLLGVLAALYWFAKKRKTTFFVVSDLVAPLVPFGLAFGRLGNFINGELWGRPTDLPWAMAFPLVDSVPRHPSQIYQLLGEGVLLGIALWFYAGKSRRVGQVSGFFLLGYGICRFLAEYAREPDAFLGLLGLGLSMGQWLCVPMIFFGIYLMTTFKSKSK
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YPE2_LACLC
Sequence: TTAIEPFISLGDK
What are the official names of this protein?
Uncharacterized protein in pepT 5'region, ORF2.
Protein: BIPC_BURMA
Sequence: MSIGVQSSGINISHAELSRLVDAGKSEQGDKAVRDDGRALARADAALAAVVGERVAARRDAVAGSGAQRVELARPKPDAQTRATDRRTVSGLEREHKRLAASQTPRVTGMHDALVQRHVSLDGAKAAHGEGVKRAAGDAPRAAADAPQRFAFADDKAFDAMLALGAAMQKNVQSDLAMQGKLTMLAHDAMMSAAAQDRSIGAAQMTAAIAGGALQATTSLGGAMQQMKSLSTKSMSIEKELKPQAELKQFHAEQALELRGINKPVLSNDEVSHVKIKRDTGETVRHEIDHGGERMSDEHASVLAQEAPARQHRIDMHGMRHEENLVKAGRQQMKGDLLQSGGQIGKNQIDGASAQQQGADRAEQKEDENAQQTAMAAASTRDEAAHRSREAAQKAIDAAKSQVANDNAVAAQVAGNLRT
What are the official names of this protein?
Effector protein BipC.
What is the protein family that this protein belongs to?
Belongs to the invasin protein C family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the bsa type III secretion system.
Protein: RISB_MYCSK
Sequence: MSGGAGVPDLPQIDASGMKVGIVASTWHSTICDALLDGALKVTESANVSEPTVVRVLGAIEIPVVAQALAADHEAVIALGVVIRGQTPHFDYVCDAVTQGLTRVSLDASTPVANGVLTTNTEEQALDRAGLPGSAEDKGAQAAAAALSTALTLQGLRGRS
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: RF3_SHEDO
Sequence: MLGNHAEVDIRRTFAIISHPDAGKTTITEKVLLFGQAIQVAGTVKGRGSKQHAKSDWMEMEKDRGISITTSVMQFPYKDCLVNLLDTPGHEDFSEDTYRTLTAVDSCLMVIDAAKGVEDRTRKLMEVTRLRDTPIITFMNKCDRDIRDPMEVMDEVENELKIACAPITWPIGCGKSFKGVYHLHRDETILYQSGLGHMMQEVRIVKGLDNPELDKAIGSELAEQLREELELVIGASHEFELAAFLKGELTPVYFGTALGNFGVDHMLDGLTQWAPKPQPRQTEVREVTSLDSDFSGFIFKIQANMDPKHRDRVAFMRVVSGKYEKGMKMHHVRVGKDVRISDALTFVAGDREQVEEAYPGDIIGLHNHGTIQIGDTFTQGEKLKFTGIPNFAPEMFRRIRLKDPLKQKQLLKGLVQLAEEGAVQVFRPLDNNDLIVGAVGVLQFEVVVGRLKSEYNVEAIYEAINVSTARWVYCKDERKLEEFRRKCSVNLALDGGNNLTYIAPTMVNLNLSMERYPDVAFAKTREN
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTURN_RAT
Sequence: MDFQQLADVAEKWCSSTPFELIAAEETERRMDFYADPGVSFYVLCPDNGCGDSFHVWSESEDCLPFLQLAQDYISSCGKKTLQEVLEKVFKSFRPLLGLPDADDDAFEEYSADVEEEEPEADHPQMGVSQQ
What is the function of this protein?
Promotes megakaryocyte differentiation by enhancing ERK and JNK signaling as well as up-regulating RUNX1 and FLI1 expression (By similarity).  Represses NF-kappa-B transcriptional activity by inhibiting phosphorylation of RELA at 'Ser- 536' (By similarity).  May be involved in early neuronal development (By similarity).
What are the official names of this protein?
Maturin, Maturin neural progenitor differentiation regulator protein homolog.
What is the protein family that this protein belongs to?
Belongs to the MTURN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WAPB_CRYNI
Sequence: MSSGGLLLLLGLLTLPAELTPISGQDRPIKPGLCPPRPQKPPCVKECKNDRSCPREQKCCRYGCIYECRDPIFVK
What is the function of this protein?
Damages membranes of susceptible bacteria.  Has no hemolytic activity.  Not toxic to mice.  Does not inhibit the proteinases elastase and cathepsin G.
What are the official names of this protein?
Nigwaprin-b.
What is the protein family that this protein belongs to?
Belongs to the snake waprin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GAT12_ARATH
Sequence: MEDEAHEFFHTSDFAVDDLLVDFSNDDDEENDVVADSTTTTTITDSSNFSAADLPSFHGDVQDGTSFSGDLCIPSDDLADELEWLSNIVDESLSPEDVHKLELISGFKSRPDPKSDTGSPENPNSSSPIFTTDVSVPAKARSKRSRAAACNWASRGLLKETFYDSPFTGETILSSQQHLSPPTSPPLLMAPLGKKQAVDGGHRRKKDVSSPESGGAEERRCLHCATDKTPQWRTGPMGPKTLCNACGVRYKSGRLVPEYRPAASPTFVLAKHSNSHRKVMELRRQKEMSRAHHEFIHHHHGTDTAMIFDVSSDGDDYLIHHNVGPDFRQLI
What is the function of this protein?
Transcriptional activator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters.  May be involved in the regulation of some light-responsive genes (By similarity).  Transcription activator involved in xylem formation.  Functions upstream of NAC030/VND7, a master switch of xylem vessel differentiation (PubMed:25265867).
What are the official names of this protein?
GATA transcription factor 12.
What is the protein family that this protein belongs to?
Belongs to the type IV zinc-finger family. Class A subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS7_CHLTE
Sequence: MAKKGSGYGPRGGDFRYNDEAVARLINAIMLDGKKVVATKIVYDAFDIIANKVEGGDALEVFRKAMGNVAPLVEVRSKRVGGATYQIPMEVPASRRTALAFRWIKQFAARRGGRSMAEKLAAELLDASNEQGASVKKRDEVHRMAEANKAFAHFRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: GLGC_EXIS2
Sequence: MAKKNVVAMLLAGGEGKRLGALTKHTAKPAVAFGGKYRIIDFPLSNCTNSGIDTVGVLTQYEPLELNRYLGIGSAWDLDRRNGGLTILPPYQAQNGKNWYEGTANAIYRNMSYINQYDPDYVLVLSGDHIYKMDYEKMIEEHRQGGADVTISVREVPWEEAPRFGILNTDEDLRINEFEEKPENPKSNLASMGIYVFNWDVLKRHLIQDAGDAESSFDFGKNIIPNMLYENLNIRAYKFKGYWKDVGTIQSLWEANMDLLEADPEFDLYEPSWKVHSVNPNQQPQYIGNNASIETSIINEGCHIEGEINHSVLFYGVDVAEGSLVKDSVIFPNVKIGKDVTIHRAILADGVVVEDGATIGTPNGEVFVIEANSVIPKNEVVKEAIQ
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: XERDL_STRE4
Sequence: MIAFIEPFLASKSLANNSQQSYRYDLRQFCQQVGQRINPETLALYQQSLSGLTVAAKKRKLSTVNQFLYYLYQQKALTDYFKMDDRIEASFSLKPQLTRLDTSAFYAETAFLKGQLIALLILELGLTPSEIAGLRLADFDLGLQVLRLQSHRGIRVMTLSKALLPFLEKATEAQQLYLFDHDAKPFSRQWFFNQLRDFLESIGCAELSAQSLREQFILNEKAAGKSIIEVAQLLGLKSPITLEKYYKM
What is the function of this protein?
Putative tyrosine recombinase.  Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site.
What are the official names of this protein?
Tyrosine recombinase XerD-like.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerD-like subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISK5_HUMAN
Sequence: MKIATVSVLLPLALCLIQDAASKNEDQEMCHEFQAFMKNGKLFCPQDKKFFQSLDGIMFINKCATCKMILEKEAKSQKRARHLARAPKATAPTELNCDDFKKGERDGDFICPDYYEAVCGTDGKTYDNRCALCAENAKTGSQIGVKSEGECKSSNPEQDVCSAFRPFVRDGRLGCTRENDPVLGPDGKTHGNKCAMCAELFLKEAENAKREGETRIRRNAEKDFCKEYEKQVRNGRLFCTRESDPVRGPDGRMHGNKCALCAEIFKQRFSEENSKTDQNLGKAEEKTKVKREIVKLCSQYQNQAKNGILFCTRENDPIRGPDGKMHGNLCSMCQAYFQAENEEKKKAEARARNKRESGKATSYAELCSEYRKLVRNGKLACTRENDPIQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGKSRNKRQSKSTASFEELCSEYRKSRKNGRLFCTRENDPIQGPDGKMHGNTCSMCEAFFQQEERARAKAKREAAKEICSEFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCASVFKLEEEEKKNDKEEKGKVEAEKVKREAVQELCSEYRHYVRNGRLPCTRENDPIEGLDGKIHGNTCSMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQNGKLFCTRENDPVRGPDGKTHGNKCAMCKAVFQKENEERKRKEEEDQRNAAGHGSSGGGGGNTQDECAEYREQMKNGRLSCTRESDPVRDADGKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTGSESGKDTCDEFRSQMKNGKLICTRESDPVRGPDGKTHGNKCTMCKEKLEREAAEKKKKEDEDRSNTGERSNTGERSNDKEDLCREFRSMQRNGKLICTRENNPVRGPYGKMHINKCAMCQSIFDREANERKKKDEEKSSSKPSNNAKDECSEFRNYIRNNELICPRENDPVHGADGKFYTNKCYMCRAVFLTEALERAKLQEKPSHVRASQEEDSPDSFSSLDSEMCKDYRVLPRIGYLCPKDLKPVCGDDGQTYNNPCMLCHENLIRQTNTHIRSTGKCEESSTPGTTAASMPPSDE
What is the function of this protein?
Serine protease inhibitor, probably important for the anti-inflammatory and/or antimicrobial protection of mucous epithelia.  Contribute to the integrity and protective barrier function of the skin by regulating the activity of defense-activating and desquamation-involved proteases.  Inhibits KLK5, it's major target, in a pH-dependent manner.  Inhibits KLK7, KLK14 CASP14, and trypsin.
What are the official names of this protein?
Serine protease inhibitor Kazal-type 5, Lympho-epithelial Kazal-type-related inhibitor, LEKTI.
What are the subcellular locations of this protein?
Secreted.
Protein: FABP9_HUMAN
Sequence: MVEPFLGTWKLVSSENFEDYMKELGVNFAARNMAGLVKPTVTISVDGKMMTIRTESSFQDTKISFKLGEEFDETTADNRKVKSTITLENGSMIHVQKWLGKETTIKRKIVDEKMVVECKMNNIVSTRIYEKV
What are the official names of this protein?
Fatty acid-binding protein 9, Testis lipid-binding protein, TLBP, Testis-type fatty acid-binding protein, T-FABP.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS_GEOSM
Sequence: MSEMTPMMRQFLEIKAEHPDAILFFRCGDFYEMFLDDAVKASRILGITLTSRNKNADGSEVPLCGIPYHSCAPYIAKLVEAGEKVAICEQAEDPKQAKGIVKREVVKVITPGLVIEDASLSPKENNYLLALCCDGECYGLSYLDLSTGEFRVTELDGLQAALAEVTCIGPREIILPVCFREEPKRKEVAHVIVDRSITYFEEWVYDPDYCKRLVANQFKGATAESLGCDRLPTALLAAGAVLHYLVDTQKGHAPHVTCITPYNESEHLLLDESTRRNLELTATLSEGKRKGSLLGLMDRTVTAMGGRKLKQWINYPLMDLKKIWLRQDAIQELMEAPGTREAMKSLLAGVYDLERLNGRISLASASAKDLSALRSSLSRLPAIKEQVAACGAGLLKELDAGIDPLDELSDLISSAIVDDPPFVLRDGGIIADGYNQELDELRAISREGKGFIARLEAQEKGRTGISSLKIRYNKVFGYYIEVTKANVSAIPDDYIRRQTLANAERYITPELKEYEEKVLGAEDRIKDLEFSLFQEVREAAAAQGERIARSADRLACLDVLVSLSELAHDKGYCRPEVHEGSELSITEGRHPVIEDMHSAERFVPNDTLLDNGENQLIIITGPNMAGKSTFMRQVALISLMAQMGSFVPADKALIPLVDRIFTRVGASDNLARGHSTFMVEMMESAAILRGATARSLVILDEIGRGTSTFDGVSIAWAVAEFLHDNKIHAAKTLFATHYHELTELAVTRPGIKNFNIAVREWNERIIFLRKIVPGGASHSYGIQVARLAGLPQAVIDRAKEILINLEKGEYGEGGVPRLARGKKTPPPSPQLSLFGAGDDQIRERLKEIEVALLTPLEALNLVDELKRMI
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: TRPA_STAA2
Sequence: MTKLFIPYIMGNKDLIENATLLSENGADIIEIGVPFSDPVADGPVIMEAGQQAIKQGITIDYIFNQLEKHGDQIKCNYVLMTYYNIICHYGEQAFFEKCRDTGVYGLIIPDLPYELSQRLKQQFSHYGVKIISLVAMTTDDKRIKDIVSHAEGFIYTVTMNATTGQNGAFHPELKRKIESIKAIANVPVVAGFGIRTPQHVADIKEVADGIVIGSEIVKRFKSNTREEIIRYLQSIQQTLNN
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: MTNC_SHESM
Sequence: MGIRAIVVDTAGTTTDLTFIQDVLFPYSVKALPDFLAQNQHNVLVENCICDTRDIALEPDADLARVTEILQQWVHEDRKATPLKTLQGLIWKQGYAHGEFTGHIFPDFIEAVNRFSAQKLRIYSFSSGSVEAQKLLFSHSDGGDLTEMFSGHFDTRTGNKLDKQAYANILNTISLSPKQVLFVSDVVEELKAAEAAGMMTCQMVRDSKQRTGDFRTINSFDELVID
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
Protein: RL35_FLAPJ
Sequence: MPKMKTKSSAKKRFKVTGSGKIKRKHAFKSHILTKKSKKRKLALTHSALVHATDMKSIKQQLRII
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: 2SS_MATST
Sequence: DQASMQRASRLLHQCDLRPRDCARRSSERGQGERWRQQLRACDEDSEPRQQCCQNLQRISSQDRCRA
What is the function of this protein?
This is a 2S seed storage protein.
What are the official names of this protein?
2S seed storage albumin protein, Matteuccin.
What is the protein family that this protein belongs to?
Belongs to the 2S seed storage albumins family.
What are the subcellular locations of this protein?
Vacuole, aleurone grain.
Protein: YH050_YEAST
Sequence: MMPAKLQLDVLRTLQSSARHGTQTLKNSNFLERFHKDRIVFCLPFFLALFLVPVQKVLQHLCLRFTQVAPYFIIQLFDLPSRHAENLAPLLASCRIQYTNCFSSSSNGQVPSIISLYLRVDLSPFYAKKFQIPYRVPMIWLDVFQVFFVFLVISQHSLHS
What are the official names of this protein?
Putative UPF0479 protein YHL050W-A.
What is the protein family that this protein belongs to?
Belongs to the UPF0479 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: COBS_MYCTA
Sequence: MMRSLATAFAFATVIPTPGSATTPMGRGPMTALPVVGAALGALAAAIAWAGAQVFGPSSPLSGMLTVAVLLVVTRGLHIDGVADTADGLGCYGPPQRALAVMRDGSTGPFGVAAVVLVIALQGLAFATLTTVGIAGITLAVLSGRVTAVLVCRRLVPAAHGSTLGSRVAGTQPAPVVAAWLAVLLAVSVPAGPRPWQGPIAVLVAVTAGAALAAHCVHRFGGVTGDVLGSAIELSTTVSAVTLAGLARL
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GMHA_ECOSM
Sequence: MYQDLIRNELNEAAETLANFLKDDANIHAIQRAAVLLADSFKAGGKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDVSHISCVGNDFGFNDIFSRYVEAVGREGDVLLGISTSGNSANVIKAIAAAREKGMKVITLTGKDGGKMAGTADIEIRVPHFGYADRIQEIHIKVIHILIQLIEKEMVK
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2C_SCHPO
Sequence: MGRVIRAQRKSGGIFQAHTRLRKGAAQLRTLDFAERHGYIRGVVQKIIHDPGRGAPLAKVAFRNPYHYRTDVETFVATEGMYTGQFVYCGKNAALTVGNVLPVGEMPEGTIISNVEEKAGDRGALGRSSGNYVIIVGHDVDTGKTRVKLPSGAKKVVPSSARGVVGIVAGGGRIDKPLLKAGRAFHKYRVKRNCWPRTRGVAMNPVDHPHGGGNHQHVGHSTTVPRQSAPGQKVGLIAARRTGLLRGAAAVEN
What are the official names of this protein?
60S ribosomal protein L2-C, K37, K5, KD4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RS8_GLOVI
Sequence: MAVNDTLADMLTRIRNASIVKHDIVPVPSTRMTRSVAEVLKMEGLILEYQDQGEGKDRQLLLTLKYAGRQRRPLITNLKRVSRPGLRVYANRKELPRVLGGIGIAIISTSQGVMTDRDARRAGVGGEVLCYVF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.