PharMolix/UniProtQA huggingface dataset:
Protein: RNMG_ASPFU
Sequence: MVAIKNLFLLAATAVSVLAAPSPLDARATWTCINQQLNPKTNKWEDKRLLYSQAKAESNSHHAPLSDGKTGSSYPHWFTNGYDGNGKLIKGRTPIKFGKADCDRPPKHSQNGMGKDDHYLLEFPTFPDGHDYKFDSKKPKEDPGPARVIYTYPNKVFCGIVAHQRGNQGDLRLCSH
What is the function of this protein?
This purine-specific ribonuclease cleaves 28S RNA in eukaryotic ribosomes, inhibits protein synthesis, and shows antitumor activity.
What are the official names of this protein?
Ribonuclease mitogillin, Allergen Asp f I, Allergen I/a, IgE-binding ribotoxin, Major allergen Asp f 1.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease U2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RECR_BACC1
Sequence: MHYPEPISKLIDSFMKLPGIGPKTAVRLAFFVLDMKEDDVLGFAKALVNAKRDLAYCSVCGHITDRDPCYICNDSHRDQSVVCVVQEPKDVIAMEKMKEYQGVYHVLRGAISPMEGIGPEDINIPQLLKRLHDETVQEVILATNPNIEGEATAMYISRLLKPTGIKVTRIAHGLPVGGDLEYADEVTLSKALEGRREV
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: NOMT5_NARAP
Sequence: MGASIDDYCLIHKKILHSEDLLKYILETSAYPREHEQLKGLREVTEKHEWSSALVPADEGLFLSMLLKLMNAKRTIEIGVYTGYSLLTTALALPEDGKITAIDVNKSFFEIGLPFIQKAGVEHKINFIESEALPVLDQMLQETKEEDLYDYAFVDADKSNYANYHERLVKLVRIGGAILYDNTLWYGSVAYPEYPGLHPEEEVARLSFRNLNTFLAADPRVEISQVSIGDGVTICRRLY
What is the function of this protein?
4'-O-methyltransferase converting norbelladine to 4'-O-methylnorbelladine (By similarity).  4'-O-methylnorbelladine is a precursor to all Amaryllidaceae alkaloids such as galanthamine, lycorine and haemanthamine, and including haemanthamine- and crinamine-type alkaloids, promising anticancer agents (By similarity).
What are the official names of this protein?
Norbelladine 4'-O-methyltransferase 5, NpN4OMT5.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
Protein: Y2948_BRUAB
Sequence: MLNRFIAFFRSVFLIGLVATAFGALPARAANETAPDYALSMHGDVALPADYTHFPYTNPDAPKKGSLTVGVVGTFDSLNPFVLKSMRTTARGLYNDGEFGNMVYQTLMLRSRDEPFTLYSLLAEKVAIDPERKWVEFTLNPKAKWSDGQPVTVDDVLFTYDILTEKGRPPYNSRMSRVAKIEKTGERSVRFTFNEKSDREFPMLIAGSMPVLPKHAINRDTFGNSTLEPPIGSGPYVVASVQPGQRIVYKRNPDYWGKDLPSQRGFNNFDKISIEYYRNETSLFESFKKGILDIFIEGNPIRWEKLYDFPAVEQGKVIKDTFEKGTPADMLGFVFNTRRPIFADRRVRQALGLLFDFEWANSNLFAGQYRRTQSFWEGAQLSSVGRPADARERELLAPFPGAVREDVMNGTWHPPVTDGSGHDRVPAKKAYDLLSQAGFQFKDGMAIDPTGKPFAFEIMTRSPDEEKIALAYQRNLSRLGIAVEIHTVDDAQYQQRLQTFDYDMILGALASSLSPGNEQWLRWGSASRDVQGSFNFAGVADPAVDAMIEALLAARNRADFVSAVRALDRVLISGDYYVPLYHLPYQWVARWDRIEHPQKTPLSGYQLPAWWHTSQ
What are the official names of this protein?
Putative binding protein BruAb2_0648.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 5 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: YCF3_NYMAL
Sequence: MPRSRINGNFIDKTSSIVANILLRIIPTTSGEKEAFTYYRDGMSAQSEGNYAEALQNYYEAMRPEIDPYDRSYILYNIGLIHTSNGEHTKALEYYFRALERNPFLPQASNNMAVICHYRGEEAIRQGDSEIAEAWFDQAAEYWKQAIALTPGNYIEAQNWLKITGRFE
What is the function of this protein?
Essential for the assembly of the photosystem I (PSI) complex.  May act as a chaperone-like factor to guide the assembly of the PSI subunits.
What are the official names of this protein?
Photosystem I assembly protein Ycf3.
What is the protein family that this protein belongs to?
Belongs to the Ycf3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: FOLE_YEASO
Sequence: MHIGKKNYPNLITSFRMNLKKIILNHDRFSHPERWKTNALLRFTFVYIKFLFDLMIIKNPLRMVGKTYRDAVTALNSLQSNYANIMAIRQTGDRKNTMTLLEMHEWSRRIGYSASDFNKLNIVHITGTKGKGSTAAFTSSILGQYKEQLPRIGLYTSPHLKSVRERIRINGEPISEEKFAKYFFEVWDRLDSTTSSLDKFPHMIPGSKPGYFKFLTLLSFHTFIQEDCKSCVYEVGVGGELDSTNIIEKPIVCGVTLLGIDHTFMLGDTIEEIAWNKGGIFKSGAPAFTVEKQPPQGLTILKERAEERKTTLTEVPSFKQLENVKLGIAGEFQKSNASLAVMLASEILHTSNILEEKIKCSSNASIPEKFIIGLQNTKWEGRCQVLEKGKNVWYIDGAHTKDSMVAASTWFRDTVRLSKRKKILLFNQQSRDANALVNNLYSSVSPEITFDDVIFTTNVTWKSGSYSADLVSMNTSQEDVEKLKVQESLVKNWNKIDDNRAKTHVTASIEEANELIETLYDEPADIFVTGSLHLVGGLLVVFDRIDVK
What is the function of this protein?
Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis.  Required for methionine synthesis and maintenance of intact mitochondrial DNA.  Involved in telomere maintenance (By similarity).
What are the official names of this protein?
Folylpolyglutamate synthase, Folylpoly-gamma-glutamate synthetase, FPGS, Tetrahydrofolylpolyglutamate synthase, Tetrahydrofolate synthase.
What is the protein family that this protein belongs to?
Belongs to the folylpolyglutamate synthase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane. Mitochondrion matrix. Cytoplasm.
Protein: UBC19_ARATH
Sequence: MATVNGYTGNTPAATTPAATGSKQSAPPTKTVDSHSVLKRLQSELMGLMMGADPGISAFPEEDNIFCWKGTITGSKDTVFEGTEYRLSLTFSNDYPFKSPKVKFETCCFHPNVDLYGNICLDILQDKWSSAYDVRTILLSIQSLLGEPNISSPLNNQAAQLWSNQEEYRKMVEKLYKPLNA
What is the function of this protein?
Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.  Part of the anaphase-promoting complex (APC).  May have a key function during cell cycle and be involved in cyclin B1 degradation.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 19, E2 ubiquitin-conjugating enzyme 19, Ubiquitin carrier protein 19.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: URDA_STREP
Sequence: MKLVAIVGTNAKQSYNRSLLQFMQRHFATKADIEILEITDVPMFNETDDQTDTPVIQKFNQAISEADGVIISTPEHNHTIPSSLNSLIEWLSFNIHPLDGKPTMIVGASYDVQGSSRAQLHLRQILDAPGVNATVMPGSEFLLGRAHRAFDENGDLIDERTVDFLDSCFYRFLRFVSVANQLNLPEEIRFEPGTYHVTTEGHNGKLPMDVTVSEDRIEKIEIDSSGESSGIADVVFTRIPAEIIEGQTLNVDAVSGASVTSNGVLDGVARAVKQAGANPDVLRKRSKAPSALDKEDKTYQADVVIVGGGGAGLAAAAAVLQAGKKPIVVEKFPAIGGNTVRAGGPMNAPDPAWQGTFEAHPGEANTLQELIAIDESTIDPEYLEDFRALKVEVEQYLQDPSYLFDSTLLYRIQTYIGGKRKDLQGHEIHGQYDLVSVLTERALESVRWLEDIGVEFVRSEVTMPVGALWRRGHKPVQPMGYAFISVLQKYVLENGGKILTDSPVKELLVEEGTVKGVRAEGRNGQTILVHADAVVLASGGFGANTKMLQKYNTYWTEIADDIATSNTPAVTGDGILLGQSVGADLVGMGFSQMMPVSDPVTGALFSGLQVPPANFIMVNTEGKRFVDEYGSRDKLSQAAIDNGGLFYLIADDRIKATAYNTSQEKIDAQVKAGTLYRADTIEELAVQIGMDPQVLADTIKKYNSYVDAGFDPEFNKGSFDLKCEVAPFYATPRKPAVHHTMGGLKIDTSTHVLNEKGQIIPGLYAAGEVAGGLHAGNRLGGNSLTDIFTFGRIAGQTAVKENC
What is the function of this protein?
Catalyzes the two-electron reduction of urocanate to dihydrourocanate (also named imidazole propionate or deamino-histidine).  Dihydrourocanate is present at higher concentrations in subjects with type 2 diabetes, and directly impairs glucose tolerance and insulin signaling at the level of insulin receptor substrate (IRS) through activation of p38 gamma (MAPK12)-p62-mTORC1.  Therefore, the UrdA enzyme from the gut bacteria S. parasanguinis strain ATCC 15912 may contribute to the pathogenesis of type 2 diabetes by producing the microbial metabolite dihydrourocanate.
What are the official names of this protein?
Urocanate reductase.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
Protein: Y1197_BACCR
Sequence: MQNKIQVKSVEKRENALIFCAENSEIEVKELSARNHVLVDSDNLSFLYILENESSFIYVSIPHTCWEAMHEAMNNDVVMFVRVNDIEMELEGLKEEVEYLVENIEGNANYGEELVTAVEKVFL
What are the official names of this protein?
UPF0738 protein BC_1197.
What is the protein family that this protein belongs to?
Belongs to the UPF0738 family.
Protein: EAMA_SALTY
Sequence: MSRKDGFLALLVVVVWGLNFVVIKVGLHHMPPLLLAGLRFLLVAFPAIFFVARPKVPLTLLLGYGLTISFGQFAFLFCAIKFGMPAGLASLVLQAQAFFTMALGAFVFSERLQRKQLAGIALAIIGVLVLIEASLNGQHIAMSGFMLTLAAAFSWACGNIFNKKIMQHSPRPAVMSLVVWSALIPILPFLLSSLLLEGADHITQSLITIDMTTILSLLYLAFVATILGYGIWGALLGRYETWRVAPLSLLVPVVGLASAAVLLGETLTGMQLAGAVLIMAGLYINVFGFRVRRTARVSG
What is the function of this protein?
May be an export pump for several amino acids and their metabolites, including cysteine.
What are the official names of this protein?
Probable amino-acid metabolite efflux pump.
What is the protein family that this protein belongs to?
Belongs to the EamA transporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RFXK_MOUSE
Sequence: MEPTQVAENLVPNQQPPVPDLEDPEDTRDESPENSDTVVLSLFPCTPDAVNPEADASASSLQGSFLKHSTTLTNRQRGNEVSALPATLDSLSIHQLAAQGELSQLKDHLRKGACPACTCLSGNNLINKPDERGFTPLIWASAFGEIETVRFLLDWGADPHILAKERESALSLASMGGYTDIVRLLLDRDVDINIYDWNGGTPLLYAVRGNHVKCVEALLARGADLTTEADSGYTPMDLAVALGYRKVQQVMESHILRLFQSTLGPVDPE
What is the function of this protein?
Activates transcription from class II MHC promoters.  Activation requires the activity of the MHC class II transactivator/CIITA.  May regulate other genes in the cell.  RFX binds the X1 box of MHC-II promoters (By similarity).  May also potentiate the activation of RAF1 (PubMed:10329666).
What are the official names of this protein?
DNA-binding protein RFXANK, Ankyrin repeat-containing adapter protein Tvl-1, Regulatory factor X subunit B, RFX-B, Regulatory factor X-associated ankyrin-containing protein.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL28_BACCR
Sequence: MARVCAITGRKARSGNSRSHAMNATKRKWGANLQKVRVRIDGKVQRVYVSARALKSGKIERV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: FABH_CLOB8
Sequence: MSNIKIAGIGAYLPSLVVTNDRISEFVETSDEWIVQRTGMRERRISEGENTSDISTKAAKLALERAGIDAKDLELIIVATISPDMFIPSVACLVQSNLDASKAACFDISVACSGFVYGLETAKALMMSMNYKNALVVGAEVLSKVTDWTDRSTCILFGDGAGAAVLKRDEAPGIIKSYLRADGKKGEALTIGATDFDTPFSKEKKLAKRTIDMNGREILRFAVSAIDEAVTEVMKDTNVSFDDIKYIVPHQANYRIIKLAAEKLKLSEDKFYLNLEKVGNTSAATVPIALNEMYEKGLLNKGDKIILVAFGGGLTYAATLLEW
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SERC_MYCPA
Sequence: MSMADQLQIPADIKPRDGRFGCGPSKVRPEQLQALSTTAAPLFGTSHRQAPVKNLVGRLRSGLAELFSLPDGYQVILGNGGATAFWDAAAFGLIDKRSLHLSYGEFSSKFAAAVAKNPFVGDPVVIKSDAGSAPEPQSDPSVDLIAWAHNETSTGVAVPVRRPVDSGDALVAIDATSGAGGLPVDIGETDAYYFSPQKNFAGDGGLWLALMSPAALARVESIAASGRWVPDFLSLPIAVENSLKDQTYNTPAIGTLALMAEQVDWMLGNGGLDWAVKRTADSAGRLYSWAEERDYTTPFVADPKLRSQVVGTIDFVDDVDAAAVAKILRANGVVDTEPYRKLGRNQLRVGMFPAVDPDDVSALTQCVDWVVERL
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Putative phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF1_RHIL3
Sequence: MEFLDATFFAFVGLVLFLALVVYLKVPGMMAKSLDDRADQIRNELAEAKRLREEAQHLLVEYQRKRKEAEAEAAHIVAAAEREAEMLTAEAMKKTEEFVANRTALSEQKIKQAEVEAMKAVRSAAVDLAIAAAETVLAKRADAKVQSELFGNAVGQVKTRLN
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b 1, ATP synthase F(0) sector subunit b 1, ATPase subunit I 1, F-type ATPase subunit b 1, F-ATPase subunit b 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: IRAK1_BOVIN
Sequence: MAGGPGPGDPAVPGAQHFLYEVPPWVMCRFYKVMDALEPADWCQFAALIVRDQTELRLCERSGQRTASVLWPWINRNARVADLVRILTHLQLLRARDIITAWHPPAPLLPPSTTSLTPSSISAPSEAAVPGHRKLPSLASTFLSPAFPGSQTHSDPELCPGPSPAAHQPPLPSPAPSSTKPSPESPMSLLPGAPSSSFCWPLHEICQGTHDFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKEEADLEWTTVKQSFQTEVQQLSRFRHPNIVDFAGYCAQSGFYCLVYGFLPNGSLEDRLHVQTQAWPPLSWPQRLDILLGTARAIQFLHQDSPSLIHGDVKSSNVLLDERLMPKLGDFGLARLSRFTGANPGQSSSVARTRTVRGTLAYLPEEYVKTGRLAVDTDTFSFGVVLLETLAGQRAVRMHGAQPKYLKDLVEEEAEEAGVTLKGTQTAVQGGPAADTWAALVAAQIYKKHLDPRPGPCPPQLGLALGQLACCCLHRRAKRRPPMTQVYQTLEELQVVVAGPCLELEAASRSPPSPQENSYVSTSGSALSRASPWQPLAAPLGAQAQATDWPQKGANQPVESDESVSDLSAALHSWHLSPSCPAGPGAPSWVPAPFGQAACTQGGAARESSCGSGPGLQPTAVEGPLLGSSMSSRPPQIVINPARRKMLQKLALYEDGVLDSLQLLSSSSLPDSGQDLQDRQGPEERDEFRS
What is the function of this protein?
Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens.  Involved in Toll-like receptor (TLR) and IL-1R signaling pathways.  Is rapidly recruited by MYD88 to the receptor-signaling complex upon TLR activation.  Association with MYD88 leads to IRAK1 phosphorylation by IRAK4 and subsequent autophosphorylation and kinase activation.  Phosphorylates E3 ubiquitin ligases Pellino proteins (PELI1, PELI2 and PELI3) to promote pellino-mediated polyubiquitination of IRAK1.  Then, the ubiquitin-binding domain of IKBKG/NEMO binds to polyubiquitinated IRAK1 bringing together the IRAK1-MAP3K7/TAK1-TRAF6 complex and the NEMO-IKKA-IKKB complex.  In turn, MAP3K7/TAK1 activates IKKs (CHUK/IKKA and IKBKB/IKKB) leading to NF-kappa-B nuclear translocation and activation.  Alternatively, phosphorylates TIRAP to promote its ubiquitination and subsequent degradation.  Phosphorylates the interferon regulatory factor 7 (IRF7) to induce its activation and translocation to the nucleus, resulting in transcriptional activation of type I IFN genes, which drive the cell in an antiviral state.  When sumoylated, translocates to the nucleus and phosphorylates STAT3 (By similarity).
What are the official names of this protein?
Interleukin-1 receptor-associated kinase 1, IRAK-1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Lipid droplet. Note=Translocates to the nucleus when sumoylated. RSAD2/viperin recruits it to the lipid droplet (By similarity).
Protein: RS18_ERWT9
Sequence: MARYFRRRKFCRFTAEGVQEIDYKDIATLKNYITESGKIVPSRITGTRAKYQRQLARAIKRARYLSLLPYTDRHQ
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: FOLD_ACISJ
Sequence: MTAQLIDGNALSRQLRTEVAARTAALKDRGITPGLAVVLVGDNPASQVYVRNKVKACEDVGFHSVLEKYDASMTEEQLLARVQALNNDPSIHGILVQLPLPKHIDDHKVIEAISPLKDVDGFHVASAGALMVGQVGFKACTPYGCMKMLESIGMKDLRGKHAVVIGRSNIVGKPMAMMLLAANATVTVCHSGTADLAAMTRQADVVVAAVGKRNVLTADMVKPGAVVIDVGMNRNDEGKLCGDVDFEGVKQVAGYITPVPGGVGPMTITMLLVNTLEAAERL
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: SYGA_SHIFL
Sequence: MQKFDTRTFQGLILTLQDYWARQGCTIVQPLDMEVGAGTSHPMTCLRALGPEPMAAAYVQPSRRPTDGRYGENPNRLQHYYQFQVVIKPSPDNIQELYLGSLKELGMDPTIHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECKPVTGEITYGLERLAMYIQGVDSVYDLVWSDGPLGKTTYGDVFHQNEVEQSTYNFEYADVDFLFTCFEQYEKEAQQLLALENPLPLPAYERILKAAHSFNLLDARKAISVTERQRYILRIRTLTKAVAEAYYASREALGFPMCNKDK
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APOA4_CANLF
Sequence: MFLKAVVLTLSLVAITGARAEVSADQVATVVWDYFSQLSNNAKEAVEHLQQSELTQQLKSVTKGHISALRVIEKGRERNSWEHSRRVGPCEIMGRQVGIFGQPLRVATLPNCDLPVNSVPPNTHLSQAVGPYAEELRTQVNTHAEQLRNQLTSHAQRMQSALRQNVDDLHSSLTPFADELKAKIDQNVEELKGHLTPYTDELKVKIDQNVEELRRSLAPYAQDVQEKLNHQLEGLAFQMKKNAEELKAKISANAEELRQRLAPVAEDVRGKLKDNTAGLHKSLAELSSRLDQQVEEFRRNVGPYGETFNKALLQQVEELRQKLGPYAGDMEDHLSFLEKDLRDKVNSFFSTLQEKESQDTPVALPKQEQEQSAVPLES
What is the function of this protein?
May have a role in chylomicrons and VLDL secretion and catabolism.  Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT.  Apoa-IV is a major component of HDL and chylomicrons.
What are the official names of this protein?
Apolipoprotein A-IV, Apo-AIV, ApoA-IV, Apolipoprotein A4.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y3775_PSE14
Sequence: MAGHSKWANIKHRKERQDAKKGKIFTKWIRELTVAARQGGGDPGSNPRLRLALDKALGANMTRDTIDRAVARGVGASDGDDVEELGYEGYGPGGVAIMVETMTDNRNRTAAAVRHAFTKCGGNLGTDGSVAYLFDRKGQISFAAGVDEDALIEAAMEADADDVVTNDDGSIDVFTSFSGFYAVRNALEAAGFKASDAEIVMLPTTSAVLDLETAEKVLKLIDMLEDLDDVQNVYSNAEIPDDVMEQLG
What are the official names of this protein?
Probable transcriptional regulatory protein PSPPH_3775.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_YERP3
Sequence: MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPTQHGEVFVTEDGAETDLDLGHYERFIRTKMTRRNNFTTGRIYSEVLRKERRGDYLGATIQVIPHITNAIKERIIEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVDVGREHTLYMHLTLVPYLAAAGEVKTKPTQHSVKELLSIGIQPDVLICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLTCPEANLAEWEQVLYEESNPGGEVTIGMIGKYVELPDAYKSVIEALKHGGLKNRLTVNIKLIDSQDVETRGEEMLKELDAILIPGGFGYRGVEGKVLAARYAREHNIPYLGICLGMQVALMEFARNVAGMENANSTEFVPDCKYPVVALITEWRDEDGNVEIRTEESDLGGTMRVGGQQCHLTEGSLVRQMYGEPTIVERHRHRYEVNNMLLKQIEAAGLRVAGRSADNKLVEIIELPDHPWFVACQFHPEFTSTPRDGHPLFAGFVKAAGDYQKRQVK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: RSD_SALA4
Sequence: MLNQLENLTERVGGSNKLVDRWLDVRKHLLVAYYNLVGIKPGKESYMRLNEKALDDFCQSLVDYLSAGHFSIYERILHKLEGNGQLLHAAKIWPLLEDNTQRIMDYYDTSLETAIDHDNCLEFQQALSDIGEALEARFVLEDKLIMLVFDAMHDGARVKRPA
What is the function of this protein?
Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA.  May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.
What are the official names of this protein?
Regulator of sigma D.
What is the protein family that this protein belongs to?
Belongs to the Rsd/AlgQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRP_SHEEP
Sequence: MRSREVSLVLLALVLCPAPRGSAAPVTAGRAGALAKMYTRGNHWAVGHLMGKKSVAESPQLREEESLKEQLREYAQWEEATRNLLSLLQAKVAQGHQPPRWEPLSIHQPAWDSKDVSNFKDSGSQREGGNPQLY
What is the function of this protein?
Induces an itch response through activation of receptors present on mast cells, triggering mast cell degranulation.
What are the official names of this protein?
Gastrin-releasing peptide, GRP.
What is the protein family that this protein belongs to?
Belongs to the bombesin/neuromedin-B/ranatensin family.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic vesicle, secretory vesicle lumen. Cell projection, neuron projection. Note=In neurons of the retrotrapezoid nucleus/parafacial respiratory group, expressed on neuron projections which project into the pre-Botzinger complex.
Protein: RSMH_POLNS
Sequence: MNIAHRPVLLAEAVTALVGGPLIQNQNSENHILVIDGTFGRGGHTQALLKELNPSAHMISFDKDLDAIAVAQKINDPRLKIVHDSFAQMDQYAEAESVDGILLDLGISSPQVDEAHRGFSFRREGPLDMRMNTDHGLTAAEWLEQASLEEITHVIKTYGEERFAFQIARAIVAKREDGLPPKTTTQLASLVSSVVRTREAGQDPATRTFQALRIFINRELEDLELGLKAAMKLLKPGARLAVISFHSLEDRIVKQFMQAHAKVDVPRGLPVREKDLPQSALKIISRLKPSDAEVSENPRARSAIMRVAEKRIGAAS
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAA_OSTTA
Sequence: MTISPPEREIKTVKIVVDRDPVPTSFEKWAKPGHFSRTLAKGPATTTWVWDLHADAHDFDSHTTDLEDISRKVFSAHFGQLGVIFIWLSGMYFHGARFSNYEAWLSDPTHIKPSAQVVWPIVGQEILNGDVGGGFQGVQITSGFFQLWRGSGITSELQLYSTAIGALICAGLMFFAGWWHYHKAAPKLEWFQNVESMMNHHLAGLLGLGSLAWAGHQIHIALPVNTLLDAGVDPKEIPLPHEFMLNRALMAELYPSFAKGLTPFFTFNWTEYSDFLTFRGGLNPVTGGLWLTDMAHHHLAIAVLFLVAGHQYRTNWGIGHSMKEILEAHKGPFTGEGHKGLYEILTTSWHAQLAINLALMGSLSIIVSHHMYSMPPYPYLATDYGTQLSLFTHHMWIGGFCICGAAAHAAIFMVRDYDPATNYNNVLDRVLRHRDAIISHLNWVCIFLGFHSFGLYIHNDTMSALGRPQDMFSDTAIQLQPIFAQFVQHTHALAPELTAPTAAGSTSASWGGDIVAVGGKIAMMPISLGTSDFMVHHIHAFTIHVTVLILLKGVLFARSSRLIPDKANLGFRFPCDGPGRGGTCQVSAWDHVFLGLFWMYNSISIVIFHFSWKMQSDVWGSVTGNGVSHITGGNFAQSANTINGWLRDFLWAQSSQVIQSYGSALSAYGLIFLGAHFIWAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPAIQPRALSITQGRAVGVAHYLLGGIATTWSFFLARIIAVG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PSI-A, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RT26_MOUSE
Sequence: MLRALNRLAARPETRPPTPLLLPVRGRKTRHDPPAKSKVGRVQTPPAVDPAEFFVLTERYRQYRETVRALRLEFTLEVRRKLHEARAGVLAERKAQQAITEHRELMAWNRDENRRMQELRIARLQLEAQAQEVQKAEAQAQRAQEEQAWVQLKEQEVLKLQEEAKNFITRENLEARIEEALDSPKSYNWAVTKEGQVVRN
What are the official names of this protein?
28S ribosomal protein S26, mitochondrial, MRP-S26, S26mt.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mS26 family.
What are the subcellular locations of this protein?
Mitochondrion.