PharMolix/UniProtQA huggingface dataset:
Protein: S22A6_PONAB
Sequence: MAFNDLLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCRPPADANLSKNGGLEVWLPRDRKGQPESCLRFTSPQWGPPFPNGTEANGTGATEPCTDGWIYDNSTFPSTIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCTAFAPNFSIYCAFRLLSGMSLAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQDQSIVRTSLAVPGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSMTAELYPSMPLFIYGAVPVAASAVTVLLPETLGQPLPDTVQDLESRKGKQTRQQQEHQKYMVPLQASAQEKNGL
What is the function of this protein?
Involved in the renal elimination of endogenous and exogenous organic anions.  Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc).  Mediates the transport of prostaglandin E2 (PGE2) and prostaglandin F2-alpha (PGF2-alpha) and may be involved in their renal excretion (By similarity).  Also mediates the sodium-independent uptake of p-aminohippurate (PAH), 2,3-dimercapto-1-propanesulfonic acid (DMPS), cidofovir, adefovir, 9-(2-phosphonylmethoxyethyl) guanine (PMEG), 9-(2-phosphonylmethoxyethyl) diaminopurine (PMEDAP), ochratoxin (OTA), acyclovir (ACV), 3'-azido-3-'deoxythymidine (AZT), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), hippurate (HA), indoleacetate (IA), indoxyl sulfate (IS) and 3-carboxy-4-methyl-5-propyl-2-furanpropionate (CMPF) and edaravone sulfate.  PAH uptake is inhibited by p-chloromercuribenzenesulphonate (PCMBS), diethyl pyrocarbonate (DEPC), indomethacin, sulindac, diclofenac, carprofen, okadaic acid, benzothiazolylcysteine (BTC), S-chlorotrifluoroethylcysteine (CTFC), cysteine S-conjugates S-dichlorovinylcysteine (DCVC), furosemide, steviol, phorbol 12-myristate 13-acetate (PMA), calcium ionophore A23187, benzylpenicillin, bumetamide, losartan, probenecid, phenol red, urate, glutarate and alpha-ketoglutarate (By similarity).
What are the official names of this protein?
Solute carrier family 22 member 6, Organic anion transporter 1, Renal organic anion transporter 1, ROAT1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: URE3_YERFR
Sequence: MQLTPREVEKLMIYTLSDVAFKRKARGLKLNYPEAVSIITVTAMEGARDGKSVEDVMKEASKVLTKDDVMDGVADLIPNVQVEAIFTDGSRLVTVHDPIK
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSTS_PSEAI
Sequence: MKLKRLMAALTFVAAGVGAASAVAAIDPALPEYQKASGVSGNLSSVGSDTLANLMTMWAEEYKRLYPNVNIQIQAAGSSTAPPALTEGTANLGPMSRKMKDVELQAFEQKYGYKPTAVPVAVDALAIFVHKDNPIKGLTMQQVDAIFSATRLCGSKQDVKTWGDLGLTGDWAKKPVQLFGRNSVSGTYGYFKEEALCKGDFRPNVNEQPGSASVVQSVSQSLNGIGYSGIGYKTASVKTVALAKKEGAAFVEDNEQNALNGTYPLSRFLYVYVNKAPNKPLDPLEAQFLKLVLSKTGQQVVVKDGYIPLPAKVAEKAIKELGL
What is the function of this protein?
Binds 1 inorganic phosphate per subunit, required for phosphate transport (By similarity).  In virulent strain MDR25, which expresses very high levels of this protein, implicated in host cell adhesion; antibody fragments against this protein decrease adhesion to host cells and increase transepithelial resistance of human epithelial cell monolayers.  High-phosphate-grown MDR25 strains form smooth colonies, express less PstS, more biofilm and are less lethal in mouse infection models than high-phosphate-grown rough colonies that express more PstS, less biofilm and are more lethal in mouse infection models; whether this is phenotype is due to PstS is unknown, however feeding mice with phosphate supplements protects them from lethality.  The ability of PstS to bind phosphate may allow it to acquire phosphate from its host (PubMed:18282104).
What are the official names of this protein?
Phosphate-binding protein PstS.
What is the protein family that this protein belongs to?
Belongs to the PstS family.
What are the subcellular locations of this protein?
Periplasm. Secreted. Note=In some strains (e.g. virulent clinical strain MDR25) forms long appendages distinct from flagella or pili on the cell surface: the protein is removed from the cell surface by vigorous vortexing (2 minutes) giving a cell surface sheared protein fraction.
Protein: DMPH_PSEUF
Sequence: MNRTLTRDQVLALAEHIENAELDVHDIPKVTNDYPDMTFADAYDVQWEIRRRKEARGNKVVGLKMGLTSWAKMAQMGVETPIYGFLVDYFSVPDGGVVDTSKLIHPKIEAEISFVTKAPLHGPGCHIGQVLAATDFVIPTVEVIDSRYENFKFDLISVVADNASSTRFITGGQMANVADLDLRTLGVVMEKNGEVVELGAGAAVLGHPASSVAMLANLLAERGEHIPAGSFIMTGGITAAVPVAPGDNITVRYQGLCSVSARFI
What are the official names of this protein?
4-oxalocrotonate decarboxylase, 4-OD.
What is the protein family that this protein belongs to?
Belongs to the hydratase/decarboxylase family.
Protein: LPP1_SALPA
Sequence: MNRTKLVLGAVILGSTLLAGCSSNAKIDQLSSDVQTLNAKVDQLSNDVNAMRSDVQAAKDDAARANQRLDNQATKYRK
What is the function of this protein?
A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes.  The only protein known to be covalently linked to the peptidoglycan network (PGN).  Also non-covalently binds the PGN.  The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.
What are the official names of this protein?
Major outer membrane lipoprotein Lpp 1, Braun lipoprotein 1, BLP 1, Murein lipoprotein 1.
What is the protein family that this protein belongs to?
Belongs to the Lpp family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor; Periplasmic side. Secreted, cell wall; Peptidoglycan-anchor. Note=Attached via its lipidated N- terminus to the inner leaflet of the outer membrane. Attached to the peptidoglycan network (PGN) via its C-terminus.
Protein: CYSG_ENT38
Sequence: MDHLPIFCQLRHRDCLLVGGGDVAERKARLLLEAGARLTVNALAFDPQFNVWAQEGMLTLVQGEFDESLLDTCWLTIAATDDDDVNQRVSDACEIRRIFCNVVDAPKEASFIMPSIIDRSPLMVAVSSGGTSPVLARLLREKLEAILPQHLGQVARYAGQLRARVKTTFATIGERRRFWEKFFVNDRLAQSLANQDQQAVEETTERLLTEPLNHRGEVVLVGAGPGDAGLLTLKGLQQIQQADIVVYDRLVSDDIMNLVRRDADRVFVGKRAGYHCVPQEEINQILLREALKGKRVVRLKGGDPFIFGRGGEELETLCNAGVPFSVVPGITAASGCSAYSGIPLTHRDYAQSVRLVTGHLKTGSELDWHNLAAEKQTLVFYMGLNQAATIQEKLLEHGMQHDMPVALVENGTAITQRVVSGVLTQLGELAKQVESPALIVVGRVVELREKLNWFSNH
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: PSBN_SACOF
Sequence: METATLVAISISGLLVSFTGYALYTAFGQPSQQLRDPFEEHGD
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RPIA_STRSY
Sequence: MINLKEQVGIKAAEFVTDGMIVGLGTGSTAYYFVQEIGRRVAEEGLQITGVTTSHATAEHAASLGIPLKNIDEVEYVDLTVDGADEVDGDFNGIKGGGAALLMEKVVAVNSKDCIWIVDESKMVQTLGAFKLPVEVVQYGAENLFRLFEKKGYRPSFRMRNGKKHITDMQNFIIDLDLRRIEDTYALAEELDRTVGVVEHGLFIGLISKVIVGTPEGPNIIEKK
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: GGTA_SYNY3
Sequence: MASVSFEQVTKQFDDYVAVNNLNLEIEDGEFLVFVGPSGCGKTTSLRLLAGLETVSQGQICIGDRRVNELSPKDRDIAMVFQSYALYPHMSVYENMAFSLDLQGKPKEEIRQRVCSAAELLGIEKLLHRKPKELSGGQRQRVAVGRAIVRKPSVFLMDEPLSNLDAMLRVQARKEISKLHSDLATTFIYVTHDQVEAMTMGDRIAVMKDGILQQVDSPANLYNQPANLFVAGFIGSPAMNFFQVERLSQEGKEKLSLDGVVLPMPDSVAKNGDRPLTLGIRPENIYHPQYLPLEIEPMELPATVNLVEMMGNELIVYAQTPAGTEFVARIDPRVNIKQKDSVKFVVDTQRFYYFDREMETAIF
What is the function of this protein?
Part of the ABC transporter complex GgtABCD involved in the uptake of the osmoprotective compounds glucosylglycerol (GG), sucrose and trehalose (PubMed:9006025, PubMed:11081796).  Responsible for energy coupling to the transport system (Probable).
What are the official names of this protein?
Osmoprotective compounds uptake ATP-binding protein GgtA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MURA1_STAEQ
Sequence: MDKIVINGGNRLTGEVNVEGAKNAVLPVLTASLLASEGHSKLVNVPELSDVETINNVLSTLNANVEYDKDKNAVKVDATKTLNEEAPYEYVSKMRASILVMGPLLARLGHAIVALPGGCAIGTRPIEQHIKGFEALGADIHLENGNIYANAKDGLKGAHIHLDFPSVGATQNIIMAASLASGKSIIENVAKEPEIVDLANYINEMGGKITGAGTDTITIHGVEKLYGVEHAIIPDRIEAGTLLIAGAITRGDIFVRGAIKEHMASLIYKLEEMGVDLEYYEEGIRVTANGDLNPVDVKTLPHPGFPTDMQSQMMALLLTANGHKVITETVFENRFMHVAEFRRMNANISVEGRSAKIEGKSHLQGAQVKATDLRAAAALILAGLVAEGTTQVTELKHLDRGYVNLHGKLKSLGANIERVNR
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1, Enoylpyruvate transferase 1, UDP-N-acetylglucosamine enolpyruvyl transferase 1, EPT 1.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_CLOBB
Sequence: MPTISQLVRKGRKSTAVKSTAPALKECPQKRGVCTVVKTTTPKKPNSALRKIARVRLTNGFEVTAYIGGVGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGALDCAGVANRMQGRSKYGAKKPKQK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: TSAB_BUCBP
Sequence: MLKTILAFDTSMSVCSISLLHKNRKYNIQKECRNNHTLYLLPMIHEILKKNHVSLNEINIIATSKGPGSFSGVRIALAVAQGISLGLNLPHVISLSTILIMAEQVWNNHKISKVLAIITVNKTSVYWIQYSRNFHGLWIKKSKAIILNLSKALEKILSLKKQWALVGNGWDKFPKNILKKIFITNITFPNSKYIISLISANSIYQKKEVLHKIIPIYLNER
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaE; this reaction does not require ATP in vitro.  TsaB seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity).
What are the official names of this protein?
tRNA threonylcarbamoyladenosine biosynthesis protein TsaB, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaB.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family. TsaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y582_BACC1
Sequence: MGFPKEGEKVQIHSYKHNGSIHRMWEETTILKGTQSLVIGANDRTVVTESDGRTWITREPAICYFHANYWFNVIGMLREEGVYYYCNLSSPFAYDSEALKYIDYDLDIKVYPDMTYTLLDEDEYEKHSQIMQYPPVIDTILKRNVAQLTQWIHQRKGPFAPDFVDMWYERYLMYRN
What are the official names of this protein?
UPF0374 protein BCE_0582.
What is the protein family that this protein belongs to?
Belongs to the UPF0374 family.
Protein: HUNB_DROSL
Sequence: WYSGMFAPNIKQEPISHHHHHHHAHHSYHQHPHDSNSNSNASSPHQSPLPSPNPPSNTNLQLEQYLKQQQQQQQQQQQQQQPMDTLCAAAMTPSSSNNDQNSPLMPPGLPNPMQSIMPANLRPSPTATTTTTPAAAAPTTTAATIALQANDKLQALTPPMDVTPPKSPAKSQQSCAEREKEHDLMSNSSEDMKYMA
What is the function of this protein?
Gap class segmentation protein that controls development of head structures.
What are the official names of this protein?
Protein hunchback.
What is the protein family that this protein belongs to?
Belongs to the hunchback C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DCD_SALG2
Sequence: MRLCDRDIEAWLDEGRLSITPRPPVERINGATVDVRLGNKFRTFRGHTAAFIDLSGPKDEVSAALDRVMSDEIVLPDGEAFYLHPGELALAVTFESVTLPPDLVGWLDGRSSLARLGLMVHVTAHRIDPGWSGCIVLEFYNSGKLPLALRPGMLIGALSFEPLSGPAARPYNRRQDAKYRDQQGAVASRIDKD
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: RS15_DESAH
Sequence: MVLLAENKDEMIANFKLHDSDTGSPEVQVALLTHRISYLTEHVKVHKKDHHSRRGLLILVGRRRSLLDYLRKKDIERYRSLIERLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: HIS2_PSEA8
Sequence: MSDTLTRLAAVLEERKNAAPDSSYVASLYHKGLNKILEKVGEESVETIIAAKDAAASGDCQDLIYETADLWFHSLVMLSALGQHPQAVLDELERRFGLSGHAEKAARQPSA
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCAFB_HUMAN
Sequence: MKKKTVCTLNMGDKKYEDMEGEENGDNTISTGLLYSEADRCPICLNCLLEKEVGFPESCNHVFCMTCILKWAETLASCPIDRKPFQAVFKFSALEGYVKVQVKKQLRETKDKKNENSFEKQVSCHENSKSCIRRKAIVREDLLSAKVCDLKWIHRNSLYSETGGKKNAAIKINKPQRSNWSTNQCFRNFFSNMFSSVSHSGESSFTYRAYCTEFIEASEISALIRQKRHELELSWFPDTLPGIGRIGFIPWNVETEVLPLISSVLPRTIFPTSTISFEHFGTSCKGYALAHTQEGEEKKQTSGTSNTRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPGNSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEETAESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEERVGSSSSESCAQDLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEKGGDPLEKQDQISGLSQSEVKTDVCTVHLPNDFPTCLTSESKVYQPVSCPLSDLSENVESVVNEEKITESSLVEITEHKDFTLKTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGHVETEDVEIIATCDTFGNEDFNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTELPKTHIEQIQKHFSEDNNEMIPMECDSFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDPNSADKHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENSGNSWNKNFGSGWVSNRGRGRGNRGRGTYRSSFAYKDQNENRWQNRKPLSGNSNSSGSESFKFVEQQSYKRKSEQEFSFDTPADRSGWTSASSWAVRKTLPADVQNYYSRRGRNSSGPQSGWMKQEEETSGQDSSLKDQTNQQVDGSQLPINMMQPQMNVMQQQMNAQHQPMNIFPYPVGVHAPLMNIQRNPFNIHPQLPLHLHTGVPLMQVATPTSVSQGLPPPPPPPPPSQQVNYIASQPDGKQLQGIPSSSHVSNNMSTPVLPAPTAAPGNTGMVQGPSSGNTSSSSHSKASNAAVKLAESKVSVAVEASADSSKTDKKLQIQEKAAQEVKLAIKPFYQNKDITKEEYKEIVRKAVDKVCHSKSGEVNSTKVANLVKAYVDKYKYSRKGSQKKTLEEPVSTEKNIG
What is the function of this protein?
Plays a role in pre-mRNA alternative splicing by regulating spliceosome assembly.
What are the official names of this protein?
Protein SCAF11, CTD-associated SR protein 11, Renal carcinoma antigen NY-REN-40, SC35-interacting protein 1, SR-related and CTD-associated factor 11, SRSF2-interacting protein, Serine/arginine-rich splicing factor 2-interacting protein, Splicing factor, arginine/serine-rich 2-interacting protein, Splicing regulatory protein 129, SRrp129.
Protein: SECB_BURCM
Sequence: MSDVENQPFFNIQRVYLKDMSLEQPNSPAIFLEQDMPSVEVEVDVKAERLAESVFEVVVSGTVTAKVKDKVAFLIEAKQAGIFDIRNIPDEQLDPLVGIACPTILFPYLRSNIADAITRAGFPPIHLAEINFQALYEQRLAQLQQQAGAAGAPNGTTLN
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCD83_BOVIN
Sequence: METAAKTNKRDIQDGPPKEVKLPISEALLDYHCQIKENALEQFMARIKKLREKNQKYHERNKRLKDEQIWHIRNLLKELSEEKSEGSVVVTREEVENAMKEKWKFERDQEQNLKDMRIQISNAEKLFLEKLSEKEYWEEYKNVGSEQHGKLITSLQNDINRVKENAEKMSEQYKITLEDARKRIIRETLLQLDQKKEWATENALRFIDKGSYREIWENDWLKKEIANHRKEVEELENAIHELEEENLVLIDQLFNCRLVDLKIPRRLYLTQAVGQEVPPEVPLELSETHKVIPEKSDSQPVDIKSRDVSSISFGSSGFRLSHKDSRFGQLLKIDEEASSSIEFGASDMKYLLYEDEQDFKDYVNLGPLEVKLMTVESKKMPIHFQEKETPVKFYEDVRSPESHITYKMMKSFL
What are the official names of this protein?
Coiled-coil domain-containing protein 83.
Protein: RLMH_METM5
Sequence: MNITIISVGKIKEKYLSDAINEYSKRISRYSKLDIIEVADEKTPESPSDVEKSKILEKEAERILKHLKKDSFVITLEILGKEVTSESLAKKINDLSISGKSDITFIIGGSLGLSKNISEISDFKLSFSKMTFPHQLMRVILLEQIYRSFRIINGEPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Putative ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3SX4_MICAT
Sequence: MKTLLLTLVVVTIVCLDLGNTRICDDSNIPSERTPKRCQGGYNICYKINFPTPGYELLQIKGCAARCPTNPRFPKAECCATDNCI
What are the official names of this protein?
Three-finger toxin MALT0044C, 3FTx MALT0044C.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PUR9_CLOTE
Sequence: MIKRALISVYNKEGILEFAKFLEKNHVEIISTGGTYKHLKDNCVRVKEVSQITNFDEILDGRVKTLHPAVHGGILAIRDNKEHMDTIKDKNIEPIDMVIVNLYPFFEKIGKGLSLEEQIEFIDIGGPTMIRAAAKNFKDVVVITDPKDYKRIEEKLEKEDEIDFNNRKTLAGKVFNLMSAYDGAISKFLLEEEYPEYLSLSYKKGKDLRYGENPHQTAAFYTSLTEDGAFKDFEKLNGKELSYNNIKDMDVAWKIVGEFEEIACCALKHNSPCGVAIGDTLLESYKKAYECDPISIFGGIVAFNRKVNKETAKELVKIFLEVIIAPDYDEDALRILKGKKNLRVIKCNTKPLDKMEICKVDVGILVQSTDNALIKDMDVVTAKKPTEEEMENMIFAMKVVKYVKSNAIVVVKDKKAVGIAGGQVNRIWAACQALERGNNSVVLASDAFFPFDDVVKKASEYGIKAIIQPGGSIRDKDSIEECDEKGISMVFTGIRHFKH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: RL18_EHRCJ
Sequence: MVSDCITRSERRKKRVRLKLRRNSSLLRLSIFKSNRHFYVQLIDDKCGRTFASASTLESEVIAVTNRKVNSNAVKIVAKLMSDRLNKLGNCKKFVFDRGPYKYTGIVSEFANELRNYGFEI
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RSMD_BUCBP
Sequence: MKILKKKSKITSIQIISGKYKNSRIPIINTKNLRPTTNYIRETLFNWISNEKIKKSHCLDCFSGSGALGIEAVSRYALSSTCIEIQKKAIFFLKKILIKLSITNVHVIRANTIQWLKKPNKSYDIIFLDPPFKTTLLKQTIALLIKNNWLKNNALIYIEQENTLNKLITPPNNWILKKEKKTKKIHYSLYMNVNNF
What is the function of this protein?
Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase D, 16S rRNA m2G966 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmD family.
Protein: PJA2_PONAB
Sequence: MSQYTEKEPAAMDQESGKAVWPKPAGGYQTITGRRYGRRHAYVSFKPCMTRHERSLGRAGDDYEVLELDDVPKENSSGSSPLDQVDSSLPNEPIFEKSETEIPTCGSALNPTTESSQSFVAVHHSEEGRDTLGSSTNLHNHSEGEYTPGACNASGVQNGIALVHTDSYDPDGKHGEDNDRLQLSAEVVEGSRYQESSGNTLFELENREAEAYTGLSPPVPSFNCEVRDEFEGLDSVPLVKSSAGDTEFVHQNSQEIQRSSQDEMVSTKQQNNTSQERQTEHSPEDSACGPGRICSEQNTNDREKNHGSSPEQVVRPKVRKLISSSQVDQETGFNRHEAKQRSVQRWREALEVEESGSDDLLIKCEEYDGEHDCMFLDPPYSRVITQRETENNQVTPESGATAGRQEVDNPFWNGCGDYYQLYDKDEDSSECSDGEWSASLPHRFSGTEKDQSSSDESWETLPGKDENEPELQSDSSGPEEENQELSLQEGEQTSLEEGEIPWLQYNEVNESSSDEGNEPANEFAQPAFMLDGNNNLEDDSSVSEDLDVDWSLFDGFADGLGVAEAISYVDPQFLTYMALEERLAQAMETALAHLESLAVDVEVANPPASKESIDGLPETLVLEDHTAIGQEQCCPICCSEYIKDDIATELPCHHFFHKPCVSIWLQKSGTCPVCRRHFPPAVIEASAAPSSEPDPDAPPSNDSIAEAP
What is the function of this protein?
Has E2-dependent E3 ubiquitin-protein ligase activity.  Responsible for ubiquitination of cAMP-dependent protein kinase type I and type II-alpha/beta regulatory subunits and for targeting them for proteasomal degradation.  Essential for PKA-mediated long-term memory processes.  Through the ubiquitination of MFHAS1, positively regulates the TLR2 signaling pathway that leads to the activation of the downstream p38 and JNK MAP kinases and promotes the polarization of macrophages toward the pro-inflammatory M1 phenotype.  Plays a role in ciliogenesis by ubiquitinating OFD1.
What are the official names of this protein?
E3 ubiquitin-protein ligase Praja-2, Praja2, RING-type E3 ubiquitin transferase Praja-2.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein. Synapse. Postsynaptic density. Note=Localizes at the cytoplasmic side of endoplasmic reticulum and Golgi apparatus. Expressed in the postsynaptic density region of synapses. Co-localizes with PRKAR2A and PRKAR2B in the cytoplasm and the cell membrane (By similarity).
Protein: MTNC_XANOM
Sequence: MTRPQAILTDIEGTTSSISFVKDVLFPYARRAMPAYVREHGNHPQVRHWLNQVADEIGEDVPDDVLITTLQTWIDEDRKHTALKALQGLIWGDGYKIADFTAHMYADAALQLQAWHAAGIPLYVYSSGSVPAQKLFFAHSDAGDLSGLVSDWFDTEVGSKREAASYRRIAERIGVPASEILFLSDVIEELDAAKRTGMRTALLERREDYPTPRSADDVGSHQRVENFSQLVF
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
Protein: SCO2_ARATH
Sequence: MFRLYPNCSLPSHRPLVFLPRLPSRSLRCRAAADIPLGDGIRLPREADSTSDTARSRDVSVAAGGNGEGAKWRKRRLLWSKSGESYLVDDGDALPLPMTYPDTSPVSPDVIDRRLQCDPVVEDCREVVYEWTGKCRSCQGSGTVSYYKKRGKEVICKCIPCQGIGYVQKITSRTDIEVMEDLDNEPS
What is the function of this protein?
Protein disulfide-isomerase involved in chloroplast development in cotyledons.  Involved in the process of vesicle-derived thylakoid formation, probably at the level of the integration and folding of LHCB proteins at the initial location of integration.  Acts only in germinating seeds after dormancy, during the transition from heterotrophic to autotrophic growth.
What are the official names of this protein?
Protein disulfide-isomerase SCO2, Protein SNOWY COTYLEDON 2.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein. Note=Associates with multiple thylakoid complexes.