PharMolix/UniProtQA huggingface dataset:
Protein: ATP8_ANOGA
Sequence: MPQMAPINWLILFIVFSITLVVFNILNYFCFFYTPLKTSQSLNIKFNKLNWKW
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: COBS_SULIN
Sequence: MRLKGVLALFSFFTAIPIKSNASLEEIAEYSYISPLIIGISLALIESAVYVLLYRILEALAGIVLLGVVELLRGFNHLDGLLDLGDALMIKGDRERKIKALKDVEIGSGGIGLLLVYLSIQIVALLKLGFSFYTIFHLISSNVLSMTIGLYILSTISPIPESNLGKIFHNKLKGKSTVLLLELIPFISLYNIIVFLVFYMIMHKICRSLGGSSGDIAGASITLSFPLFLLTNEITNLNYSLLSILCYLFLHLH
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PHNC_STAHJ
Sequence: MSQIEFKDVNKVYPNGHVGLKDINLNIEKGDFAVIVGLSGAGKSTLLRSVNRLHDITSGDILIEGKSITKAKGNDLLMMRRNIGMIFQHFNLVKRSSVLRNVLSGRVGYHPTWKMVLGLFPKEDKVKAMDALERVNILDKYDQRSDELSGGQQQRISIARALAQEPAIILADEPVASLDPLTTKQVMDDLKKINEELGITILINLHFVDLALEYGTRIIGLRAGELVFDGPASEATEEVFNDIYGRKLKDDEKLGVE
What is the function of this protein?
Part of the ABC transporter complex PhnCDE involved in phosphonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphonates import ATP-binding protein PhnC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: DPO4_SHEWM
Sequence: MKNILRKIIHIDMDCYFAAVEMRDFPELRGKPIAVGGRSDRRGVISTCNYEARAFGVRSAMASGYALKLCPDLILVPGRMSVYKEVSAQIRDIFARYTDLIEPLSLDEAYLDVTECKQCQGSATLIAQAIRQEIFEVTGLTASAGIAPVKFLAKVASDLNKPNGQYVITPDMISSFITTLPLTKIPGVGKVTGKKLEDIGLTTCGELQAYPKSELIERFGKFGKILIERAQGIDERAISPHRERKSVGVETTLAKDIYTLEQCHGVMPQLIQELGARMSRSAKGRSINKQVVKLKFNDFKQTTIEHRSDEMSVKLFYELLAQSLERQQGRGIRLLGVSVGLACQADSNTAKDNQVRESQLDLGF
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TXC4A_CUPSA
Sequence: GFGMLFKFLAKKVAKKLVSHVAQKQLE
What are the official names of this protein?
Cupiennin-4a, Cu-4a, Short cationic peptide-4a, SCP-4a.
What is the protein family that this protein belongs to?
Belongs to the cationic peptide 04 (cupiennin) family. 08 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS1_DESHD
Sequence: MARNFLTIALPKGKLLTDSLEVLTKIGIECQEVSEESRKLVFPLEKAQAQIIICRPTDIPTFVEYGAADIGFVGKDTLLEENKDVVELLDLGFGYCRFVVAMPEEKVPPRLPDGKFDLSGLNHQRVATKFPRVAEDFFREQGMQVLPIKLHGNIELAPRVGLAEMIVDIVSTGTTLRQNKLVEIAPILEATTRLIANRVAYRMKHERINELTERLRQLLGRAP
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOXE3_MOUSE
Sequence: MAVYRLCVTTGSYLKAGTLDNIYATLVGTCGESPKQKLDRVGRDFASGSVQKYKVRCEAELGEILLLRLHKERFAFFCKDPWYCSRICVTAPDGSAVHFPCYQWIDGYCTVELRPGTARTICQDSLPLLLDHRKRELQARQECYRWKIFAPGFPRMVDVSSFQEMESDKKFALTKTVPCAEQDDNSGNRYLPGFPMKIDIPSLLHMEPNIRYSATKTASLIFNALPASFGMKIRGLLDRKGSWKRLDDIRNIFWCHKTFTSEYVTEHWCEDSFFGYQYLNGVNPVMLHCLSSLPSKLPVTNDMVAPLLGPGTCLQTELERGHIFLADYWILAEAPVHCINGLQQYVTAPLCLLWLNPQGVLLPLAIQLSQTPGPESPIFLPTDCELDWLLAKTWVRNSEFLVHENNTHFLCTHLLCEAFSMATLRQLPLCHPVYKLLLPHTRYTLQVNTIARATLLNPDGLVDKVTSIGRQGLIYLMSTGLAHFTYTDFCLPDSIRARGVLTIPNYHYRDDGLKIWAAIERFVSEIVSYYYPSDASVQQDCELQAWVGEIFAQAFLGRESSGFPSRLCTPGELVKYLTAIIFNCSAQHAAVNSGQHDFGAWMPNAPSSMRQPPPQTKGDTTMKSYLDTLPEVNTTCRNLLLFWLVSQEPKDQRPLGTYPDEHFTEEAPRQSIAAFQNCLAQISKDIRERNQSLALPYAYLDPPLIENSVSI
What is the function of this protein?
Non-heme iron-containing lipoxygenase which is atypical in that it displays a prominent hydroperoxide isomerase activity and a reduced lipoxygenases activity (PubMed:17045234).  The hydroperoxide isomerase activity catalyzes the isomerization of hydroperoxides, derived from arachidonic and linoleic acid by ALOX12B, into hepoxilin-type epoxyalcohols and ketones (PubMed:17045234).  In presence of oxygen, oxygenates polyunsaturated fatty acids, including arachidonic acid, to produce fatty acid hydroperoxides.  In the skin, acts downstream of ALOX12B on the linoleate moiety of esterified omega-hydroxyacyl-sphingosine (EOS) ceramides to produce an epoxy-ketone derivative, a crucial step in the conjugation of omega-hydroxyceramide to membrane proteins (By similarity).  Therefore plays a crucial role in the synthesis of corneocytes lipid envelope and the establishment of the skin barrier to water loss (PubMed:22832496).  In parallel, it may have a signaling function in barrier formation through the production of hepoxilins metabolites (By similarity).  Also plays a role in adipocyte differentiation through hepoxilin A3 and hepoxilin B3 production which in turn activate PPARG (PubMed:20530198).  Through the production of hepoxilins in the spinal cord, it may regulate inflammatory tactile allodynia (By similarity).
What are the official names of this protein?
Hydroperoxide isomerase ALOXE3, Epidermis-type lipoxygenase 3, Epidermal LOX-3, e-LOX-3, eLOX-3, Hydroperoxy dehydratase ALOXE3, Hydroperoxy icosatetraenoate dehydratase, Hydroperoxy icosatetraenoate isomerase.
What is the protein family that this protein belongs to?
Belongs to the lipoxygenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FPRS4_MOUSE
Sequence: MEVNISMPLNGSEVVFYDSTTSRVLWILSLVVLFITFVLGVLGNGLVIWVAGFQMAHTVTTVSYLNLALSDLSFMATLPLHIISMVMRGKWLFGWFLCKLVHIIANINLFVSIFLITLIAMDRCICVLCPVWSQNHRTVSLARKVVLGAWIFALLLTLPHFLFLTTVRDARGDVYCISKFESWVATSEEQLKVSVIAATASGIINFIIGFSMPMSFIAICYGLMAAKICRRGFVNSSRPLRVLTAVAVSFFVCWFPFQLIMLLGNIFNNETLSIIHMLVNPANTLASFNSCLNPILYVFLGQEFRDRLIYSLYASLERALRED
What is the function of this protein?
May have an olfactory function associated with the identification of pathogens or of pathogenic states.
What are the official names of this protein?
Formyl peptide receptor-related sequence 4, N-formylpeptide receptor-like 4.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DUT_BURA4
Sequence: MKLDLKILDARMRDYMPAYATTGSAGLDLRACLDAPVTLQPGETTLVPTGLAIHLADPGYAALILPRSGLGHKHGIVLGNLVGLIDSDYQGQLMVSTWNRGQTEFVLNPFERLAQLVIVPVVQAQFNIVDDFAQSERGEGGFGSTGRH
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: MURQ_ECOL5
Sequence: MQLEKMITEGSNAASAEIDRVSTLEMCRIINDEDKTVPLAVERVLPDIAAAIDVIHTQVSGGGRLIYLGAGTSGRLGILDASECPPTYGVKPGLVVGLIAGGEYAIQHAVEGAEDSREGGVNDLKNIGLTAQDVVVGIAASGRTPYVIAGLEYARQLGCRTVGISCNPGSAVSSTAEFAITPVVGAEVVTGSSRMKAGTAQKLVLNMLSTGLMIKSGKVFGNLMVDVVATNEKLHVRQVNIVKNATGCNAEQAEAALIACERNCKTAIVMVLKNLDADEAKKCLDQHGGFIRKALEKE
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.  Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: T3MO_ECOLX
Sequence: MKKETIFSEVETANSKQLAVLKANFPQCFDKNGAFIQEKLLEIIRASEVELSKESYSLNWLGKSYARLLANLPPKTLLAEDKTHNQQEENKNSQHLLIKGDNLEVLKHMVNAYAEKVKMIYIDPPYNTGKDGFVYNDDRKFTPEQLSELAGIDLDEAKRILEFTTKGSSSHSAWLTFIYPRLYIARELMREDGTIFISIDHNEFSQLKLVCDEIFGEQNHVGDLVWKNATDNNPSNIAVEHEYIIVYTKNKEQLISEWKSNISDVKNLLVNIGEEFASKYTGNELQEKYTQWFREHRSELWPLDRYKYIDKDGIYTGSQSVHNPGKEGYRYDIIHPKTKKPCKQPLMGYRFPLDTMDRLLSEEKIIFGDDENKIIELKVYAKDYKQKLSSVIHLDGRVATNELKELFPEMTQPFTNAKTIKLVEDLISFACDGEGIVLDFFAGSGTTAHTVFNLNNKNKTSYQFITVQLDEPTKDKSDAMKHGYNTIFDLTKERLIRASKKNRDQGFKVYQLMPDFRAKDESELTLSNHTFFDDVVLTPEQYDTLLTTWCLYDGSLLTTPIEDVDLGGYKAHLCDGRLYLIAPNFTSEALKALLQKVDSDKDFAPNKVVFYGSNFESAKQMELNEALKSYANKKSIELDLVVRN
What is the function of this protein?
A beta subtype methylase that binds the system-specific DNA recognition site 5'-CAGCAG-3' and methylates A-5 (of only 1 strand as the other does not have an A residue).  DNA restriction requires both the Res and Mod subunits (PubMed:11178902, PubMed:12654995).  The A-5 nucleotide flips into the catalytic pocket of one Mod subunit for modification, while the other Mod subunit makes most of the DNA sequence-specific contacts (PubMed:26067164).
What are the official names of this protein?
Type III restriction-modification enzyme EcoP15I Mod subunit, M.EcoP15I, EcoP15I methyltransferase, Type III methyltransferase M.EcoP15I.
What is the protein family that this protein belongs to?
Belongs to the N(4)/N(6)-methyltransferase family.
Protein: SYL_CLOTE
Sequence: MGNYGTNIDRKWQNKWEDSNLYHFDTNNLDKKLYVLEMFSYPSGSNLHAGHWFNYGPSDSWARFKRMQGFNVFQPMGFDSFGLPAENYAIKTGVHPKDSTMKNIETMTKQLKSMGAMFHWDNEVITSEPEYYKWTQWMFLQLYKNNLAYRKNAPVNWCPSCNTVLANEQVLDGACERCSSDVIKKDLTQWFFKITDYAEELLEKLDDLDWPENTKSMQKHWIGKSIGAQLTFKIVDSDLSFDIFTTRADTLFGVTYAVLAPENPLVDKITKEDHKAEIEAYKEQAKKQSEIERQSITREKTGVFTGSYAINPINGKKVPVWVGDYVLSTYGTGAVMAVPAHDERDFEFAKKHNLPIEKVIEGGETLPYTEDGIMINSEEFNGLESSKGRSAVVEKLEKENLGVKKINYRLRDWLVSRQRYWGAPIPIVYCDKCGTVAVPEEQLPVKLPYDVEFTPDGKSPLSKCDSFVNTTCPTCGGPAKREVDTLDTFVCSSWYFLRYADNKNSEKAFDPKIINEILPVDKYVGGPEHACMHLLYARFFTKALRDMGYLNFDEPFSSLTHQGLILGPDGLKMSKSKGNTISPDDYIDEFGSDVFRMYLMFGFDYTEGGAWSDEGIKSVSRFVDRVERTLASCRYYINNPSDDKITIDNNEKDLNFVRHNSIKSITEDAEKMQFNTCIARLMEYTNALSKYINEDNKNSKFLKECVEDFIILIAPFAPHFSEEQWELLGMTYSVFNEKWPQFDSKALVKDEIEIAVQVNGKIRDRITIASGLDEESIKETALNSEDVKKYTDGKNIVKIIIIKGRLVNIVVK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KRA61_RABIT
Sequence: MCGYYGNYYGGRGYGCCGYGGLGYGYGGLGCGLGSYYGCGYRRLGCGYGCGYGYGYGSRSLCGCGYGYGSGYGSGFGYYY
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Keratin-associated protein 6-1, Keratin, glycine/tyrosine-rich of hair.
What is the protein family that this protein belongs to?
Belongs to the KRTAP type 6 family.
Protein: TAL_PSEPW
Sequence: MTSKLEQLKQFTTVVADTGDLDAITRLKPVDATTNPSLLLKAAAIPGYADLLKQVKSDAKGNVDLACDKFAVAVGAGILKVIPGRISTEVDARLSFDEPALLSKARQLIELYQAAGIPKDRVLIKLASTWEGIRAAEQLEKEGIQTNLTLLFSFAQAQACADAGVFLISPFVGRIYDWYKKSTGQEYVGANDPGVQSVTRIYNYYKANGYNTVVMGASFRNIGQIEQLAGCDRLTISPELLQQLSDDQGELPQVLKPGDAGEAKQVLSESQFRWAMNEDAMGTEKLAEGIRQFARDQEKLEKLMADKA
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_ACIBC
Sequence: MARYIGPKCKLSRREGTDLQLKSGVKPFDVKTKKANKAPGQHGQARGGKQSEYSLQLREKQKVRRIYGVLERQFSNYYKEAARVKGATGENLLKLLESRLDNVVYRMGFGSTRAEARQLVSHRSITLNGRRVNIASIQVKSGDVIAVHEGAKQQLRIKNAIELAAQRGIPAWIEVDHSKLEGTFKAAPDRSDLPAEINESLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: DNLJ_BURCH
Sequence: MARTQAEPPASQPDARAAWLRDQLERANYAYYVLDQPDLPDAEYDRLFRELQQLETDHPELVTPDSPTQRVGGEAAGGFTPVVHDAPMLSLNNGFADEDIVAFDKRVADALAKTTDLAGSVTDPVEYACELKFDGLAISLRYEQGVFVQAATRGDGTTGEDVTENVRTIRSIPLKLKGKHVPAVLDVRGEVLMFKRDFARLNERQRAAEQREFANPRNAAAGSLRQLDSKITAQRPLSFFAYGIGVLDGMPMPDTHSALLDWYESLGLPVNRERAVVHGAEGLLDFFRKVGEKRESLPYDIDGVVYKVNRRDEQERLGFVSRAPRFALAHKFPAQEALTKLVAIDVQVGRTGAITPVARLEPVFVGGATVTNATLHNEDEVRRKDIRIGDTVIVRRAGDVIPEVVGALLDRRPADAAEFVMPTECPVCGSKIERLPDEAIARCTGGLFCPAQRKQALWHFAQRRALDIDGLGEKIIDQLVELNLVRTPADLFNLGFATLAELDRFAEKSAQNLIDSLEKAKHTTLARFIYGLGIRHVGESTAKDLAKHFGSLTPIMDASIEELLEVNDVGPIVAESLHQFFAEEHNRTVIEQLRAPGKVTWPEGPPAPKAPQGVLAGKTVVLTGTLPNLTRDAAKEMLEAAGAKVAGSVSKKTDYVVAGAEAGSKLAKAEELGIPVLDEDGLHQLLEGNTP
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: DGP_CORAP
Sequence: SINNTGGSGNRRLDKNGFAGQ
What are the official names of this protein?
Dart gland peptide.
What are the subcellular locations of this protein?
Secreted.
Protein: ADD2_CAEEL
Sequence: MSDGSDDDTNNDGNYCKNVSYNFLIQRLAEVSNRKCLLLPKKKNRVDYISIMQTAEFYPELVNSSPPLEPGFTSCEVFVVDKKVDKDTLHLDNFSPYHIGATRRTLERQHSYFYRVNESGNFVPAIKTNGTHILRILVSILGSCPALNRKIYRMVKIESQNKNCLPSLIVYTFEPGHEIPKPNAPAILRRQTSDEIQKILNIPGTSFSQAHSEAVLNRFYDDLPIRDEASDQKRARYSIESTSSTNNQLNEINSFVVPKFEGRQESEQLFRDVKVEQFEESAEISINNRALSPHIQPSKTSVVNRPNQQNRKFQNYDMFSAGVISTATVPAPMFHPHITPIADLKDDDGYDPEELTQRNKLASLYRLVDLFRWSQGIYNHITVRVSTDPDEILINAFGQLYSEVSASSLIKVDLDGTVIDGGSTNFGVNQAGYVLHSAIHNGRPEVKCVVHLHHPSVVAVSAQKCGLLPISQESMIVGDVGYHEYRGILIDEAERALLVRDLGDRNVMILRNHGFVVCGESIEHALSLTYHLIIACETQIRTVPGGNTDNVHFPAQSAIKQVYKVASQGGGGVNRQNGHVNSMQWKKGELEWQAYMRQLDAQGYVTGNVPN
What is the function of this protein?
Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network.
What are the official names of this protein?
Adducin-related protein 2.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. Adducin subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SCNM1_HUMAN
Sequence: MSFKREGDDWSQLNVLKKRRVGDLLASYIPEDEALMLRDGRFACAICPHRPVLDTLAMLTAHRAGKKHLSSLQLFYGKKQPGKERKQNPKHQNELRREETKAEAPLLTQTRLITQSALHRAPHYNSCCRRKYRPEAPGPSVSLSPMPPSEVKLQSGKISREPEPAAGPQAEESATVSAPAPMSPTRRRALDHYLTLRSSGWIPDGRGRWVKDENVEFDSDEEEPPDLPLD
What is the function of this protein?
As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (PubMed:36084634).  Plays a role in the regulation of primary cilia length and Hedgehog signaling (PubMed:36084634).
What are the official names of this protein?
Sodium channel modifier 1.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus speckle. Note=Colocalizes with LUC7L2 and SNRNP70 in nuclear speckles.
Protein: GATB_PICGU
Sequence: MSFRLILDIQDQMNIVRRLHRSARLGSDLVSGFKLKCGLELHTQLKTDFKLFSLSKTSFNEPPNSSISYFDVGLPGTMPKLNPEALRLALRLAVSLDSDINLNSSFDRKHYFYPDQPLGYQITQHYSPIATGGFLKLDSRYDGIESTKKDIRIEQIQLEQDTGKTNYVKFDGEVRIDYNRANIPLIELVTKPDFETIGEVVAFIKKYQTLVKYLDVCTGDLETGAIRVDVNVSVNGGNRVEIKNLGSTSEVAEALGYEYRRQIECLKENVSILQETRSWDGKSTTASRSKEDALDYRYVPDSELPVIRLHSDIKKQVQESLPQLPDAVVEKLIASPFNIELKHAQFLVNNKHVLSYYYNLIESIKDIDVKRANNWLFHEVFGAFSKNNLAFDPDKISPSSLARLLHLIFIEKSITSASAKILLGHLVTAPNSMEIEQAMEQYDLGKPTGVSESDIDEIVDEICTEIIAANPDVIKRIKDGKHKSINYLIGQAMKETEGKVSSDIFAARFKALIGT
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial, Glu-AdT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: DEOC_CLOP1
Sequence: MDKQQLAKMIDHTILKPEADKASIEKLCKEALEYNFASVCINPTNVELAAKLLKGSEVKVCTVIGFPLGANTMEVKAFETKDAIAKGADEVDMVINIGRLKDKDYEYVEKDIKAVVDAADKKALTKVIIETCLLTEEEKVKACELAKKAGADFVKTSTGFSTGGATPEDIKLMRETVGPDMGVKASGGVRSIEDAEAVIKNGATRIGASASIAICEGKVSDSTY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_ECOL6
Sequence: MALNLQDKQAIVAEVSEVAKGALSAVVADSRGVTVDKMTELRKAGREAGVYMRVVRNTLLRRAVEGTPFECLKDAFVGPTLIAYSMEHPGAAARLFKEFAKANAKFEVKAAAFEGELIPASQIDRLATLPTYEEAIARLMATMKEASAGKLVRTLAAVRDAKEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: PSAC_NICSY
Sequence: MSHSVKIYDTCIGCTQCVRACPTDVLEMIPWDGCKAKQIASAPRTEDCVGCKRCESACPTDFLSVRVYLWHETTRSMGLAY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: AROA_SALHS
Sequence: MESLTLQPIARVDGAINLPGSKSVSNRALLLAALACGKTVLTNLLDSDDVRHMLNALSALGINYTLSADRTRCDITGNGGPLRASGALELFLGNAGTAMRPLAAALCLGQNEIVLTGEPRMKERPIGHLVDSLRQGGANIDYQEQENYPPLRLRGGFTGGDIEVDGSVSSQFLTALLMTAPLAPEDTTIRVKGELVSKPYIDITLNLMKTFGVEITNHHYQQFVVKGGQQYHSPGRYLVEGDASSASYFLAAGAIKGGTVKVTGIGRKSMQGDIRFADVLEKMGATITWGDDFIACTRGELHAIDMDMNHIPDAAMTIATTALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDYIRITPPAKLQHADIGTYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQLARMSTPA
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSRA_PSYA2
Sequence: MLILTRRVGETLMIGDEVSVTVLGVKGNQVRIGVDAPKDIAVHREEIYQRIQHERTIQSQMQHLEQGSFAPSFDDEDYFNR
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP_LOTJA
Sequence: MPIGVPKVPFRSPGEEDASWVDIYNRLYRERLLFLGQEVNSEISNQLIGLMVYLSIEDDKKDLYLFINSPGGWVIPGIAIYDTMQFVQPDVQTVCMGLAASMGSFVLAGGKITKRLAFPHARVMIHQPASSFYEAQTGEFILEAEELLKLRETITRVYVQRTGKPLWLVSEDMERDVFMSAAEAQAYGIVDLVAVE
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.