PharMolix/UniProtQA huggingface dataset:
Protein: ENO_PSET1
Sequence: MSVIVKVIGREIMDSRGNPTVEADVHLADGSWGRAAAPSGASTGTREALELRDGDKSRYLGKGVLKAVGFINNEIATALAGQNALEQSTVDQVMLDLDGTENKEKLGANAILAVSLATAKAAAQSKKVELYEHIADLNGTPGVYSMPLPMMNIINGGEHADNSVDIQEFMIQPIGAKNFREALRMGAEIFHSLAKVLKADGHSTAVGDEGGFAPNLASNEAALAAIKVAVANAGYELGKDITLALDCAASEFYDKEANIYNLKGEGKKFTSEEFNFFLQDLTQQYPIVSIEDGLDESDWDGFAHQTKLMGDKIQLVGDDLFVTNTKILKRGIDNGIANSILIKFNQIGSLTETLAAIKMAKDAGFTVVISHRSGETEDSTIADLAVGTAAGQIKTGSLSRSDRVAKYNQLLRIEEQLGDKAPYNGLKEVKGQ
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: VPS54_RAT
Sequence: MASSHSSSPVPQGSSSDVFFKKEVDPTKHVRPVQSLPDVCPKEPTVTDQHRWTVYHSKVNLPAALNDPTLAKRESDFFTKTWGLGFVDTEVIPSLYLPQISKEHFIAYQQEISQREKIHERCKNICPPKDTFDRTLLHIHDKSRTDLEQVPKIFMKPDFALDDSLTFNSVLPWSHFNTAGGKGNRDAASSKLLQEKLSHYLDIVEVNIAHQISLRSEAFFHAMTSQHELQDYLKKTSQAVKMLRDKIAQIDKVMCEGSLQILRLALTRNNCVKVSNKLKLMATVHQTQPTVQVLLSTSEFVGALDLIATTQEVLQQELQGVHSFRHLGSQLCELEKLIDKMMIAEFSTYSHSDLNRPLEGECQVLEEERLVSLVFGLLEQRKLNFLEIYGEETIITAKNIIKECVINKVAQVEEIDTDAVVKLADQMRMLNFPQWIDLLKDIFSKFTIFLQRVKATLNVIHSVVLSVLDKNQRTRELEEVSQQRSAGKDNSLDTEVAYLTHEGLFISDAFSEAEPASAAVDTTSQRNTSPHSEPCSSDSVSEPECTTDSSSSKEQTPASATLGGVDIIVSEDMRLTDLELGKLASNIQELLCNASDVCHDRAVKFLMSRAKDGFLEKLNSTEFIALSRLMETYIVDTEQICGRKSTSLLGALQSQANKFVNRFHEERRTKLSLLLDNERWKQADVPAEFQDLVDSIADGKIALPDKKPAATEDRKPADVLVVEGHQYAVVGTVLLLIRIILEYCQCVDNIPSVTTDMLTRLTDLLKYFNSRSCQLVLGAGALQVVGLKTITTKNLALSSRCLQLIVHYIPVIRAHFEARLPRKQWSLLRHFDHITKDYHDHIGEISSKLIAIMDSLFDKLLSRCEVEAPAPSPCFRNICKQMTKMHEAIFDLLPKEQTQMLILRINASYKFHLKKQLSHLNVINDGGPQSGFVTADVAFYTGNLQALKGLKDLDLNMAEIWEQKR
What is the function of this protein?
Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN).  The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD.  Within the GARP complex, required to tether the complex to the TGN.  Not involved in endocytic recycling.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 54, Vps54-like protein.
What is the protein family that this protein belongs to?
Belongs to the VPS54 family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network. Membrane. Note=Associates with membranes in an EIPR1-independent manner.
Protein: PYRB_CROS8
Sequence: MANPLYQKHIISINDLSRAELELVLETAAKLKANPQPELLKHKVIASCFFEASTRTRLSFETSMHRLGAAVVGFSDSSNTSLGKKGETLADTISVISTYVDAIVMRHPQEGAARLATEFSGGVPVLNAGDGANQHPTQTLLDLFTIQETQGRLENLTIAMVGDLKYGRTVHSLAQALAKFNGNRFCFIAPDALAMPQYILDMLDEKGIPWSLHSAIEDVVQEVDILYMTRVQKERLDPSEYANVKAQFVLRAADLQGARANMKVLHPLPRIDEITTDVDKTPHAWYFQQAGNGIFARQALLALVLNRDLAL
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: KAD_ACIAC
Sequence: MRLILLGAPGAGKGTQAAFICQKYGIPQISTGDMLRAAVKAGTPLGQQAKAVMDAGKLVSDDLIINLVKDRIAQPDCAKGFLFDGFPRTIPQADAMKAAGVKLDYVLEIDVPFDAIIERMSGRRSHPASGRTYHVKFNPPKVEGKDDVTGEDLIQREDDKEDTVKKRLEVYSAQTRPLVEYYSTWAKNDPANAPKYRAISGTGTVEEITRRALAALAD
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PXPA_BORPA
Sequence: MNPAIDLNCDMGESYGAWRMGNDEAVLQFVTSANIACGFHGGDPSTMRQTVAAALAHGVALGAHPSLPDLAGFGRRAMQITPQEAYDLVVYQVGALAGVAASQGARLHHVKAHGALYNMAAKDAALARAICQAVRDVDSDLVLYGLAGSALIDAARAIGLRAAQEVFADRTYQADGQLTPRSQPDAMITDLDQAIAQVLGMVRDGSVRTPDGQTVALQADTLCIHGDQPDALVFARGIRLALERNGIAIQAA
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: COQ5_PONAB
Sequence: MAAPRSCALWSYCGRGWSWAMRGCQLLGLRSSWPGAPLSARLLPQEKRATETHFGSETVSEEEKGGKVYQVFESVAKKYDVMNDMMSLGIHRVWKDLLLWKMRPLPGTQLLDVAGGTGDIAFRFLNYVQSQHQRKQKRQLRAQQNLSWEEIAKEYQNEEDSLGGSRVVMCDINKEMLKVGKQKALAQGYRAGLAWVLGDAEELPFDDDKFDIYTIAFGIRNVTHIDQALQEAHRVLKPGGRFLCLEFSQVNNPLISRLYDLYSFQVIPVLGEVIAGDWKSYQYLVESIRRFPSQEEFKEMIEDAGFHKVTYESLTSGIVAIHSGFKL
What is the function of this protein?
Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial, Ubiquinone biosynthesis methyltransferase COQ5.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: RLMM_ECOHS
Sequence: MNKVVLLCRPGFEKECAAEITDKAGQREIFGFARVKENAGYVIYECYQPDDGDKLIRELPFSSLIFARQWFVVGELLQHLPPEDRITPIVGMLQGVVEKGGELRVEVADTNESKELLKFCRKFTVPLRAALRDAGVLANYETPKRPVVHVFFIAPGCCYTGYSYSNNNSPFYMGIPRLKFPADAPSRSTLKLEEAFHVFIPADEWDERLANGMWAVDLGACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFKFRPTRSNISWMVCDMVEKPAKVAALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYIQAQLDEHGINAQIQARQLYHDREEVTVHVRRIWAAVGGRRDER
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHCR7_RAT
Sequence: MASKSQHNASKAKNHNVKAESQGQWGRAWEVDWFSLVSVIFLLLFAPFIVYYFIMACDQYSCSLTAPILDVATGRASLADIWAKTPPVTAKAAQLYALWVSFQVLLYSWLPDFCHRFLPGYVGGVQEGAITPAGIVNKYEVNGLQAWLITHFLWFVNAYLLSWFSPTIIFDNWIPLLWCANILGYAVSTFAMIKGYLFPTSAEDCKFTGNFFYNYMMGIEFNPRIGKWFDFKLFFNGRPGIVAWTLINLSFAAKQQELYGHVTNSMILVNVLQAIYVLDFFWNETWYLKTIDICHDHFGWYLGWGDCVWLPYLYTLQGLYLVYHPVQLSTPNALGVLLLGLVGYYIFRMTNHQKDLFRRTDGHCLIWGKKPKAIECSYTSADGLKHRSKLLVSGFWGVARHFNYTGDLMGSLAYCLACGGGHLLPYFYIIYMTILLTHRCLRDEHRCANKYGRDWERYVAAVPYRLLPGIF
What is the function of this protein?
7-dehydrocholesterol reductase of the cholesterol biosynthetic pathway reducing the C7-C8 double bond of cholesta-5,7-dien-3beta-ol (7-dehydrocholesterol/7-DHC) and cholesta-5,7,24-trien-3beta-ol, two intermediates in that pathway.
What are the official names of this protein?
7-dehydrocholesterol reductase, 7-DHC reductase, Sterol Delta(7)-reductase.
What is the protein family that this protein belongs to?
Belongs to the ERG4/ERG24 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: HUPF_BRADU
Sequence: MCLGLPMTIVETDGVSALCAFRGEQRRVSMLLLSNPPVGTHVLVYIDTAIRLLDEEEARLIGAAIDGLGAALDGEDCDRFFADLIDREPQLPAHLRSE
What are the official names of this protein?
Hydrogenase expression/formation protein HupF.
What is the protein family that this protein belongs to?
Belongs to the HupF/HypC family.
Protein: ERIC4_MOUSE
Sequence: MEPWVQLKQAGLEPSGLGPLPKALRVPPPEGNPGQALMSSGAELGGARELILWIWEELGNLRRVDVQLLGQLCDLGLEMGTFREELVTILEEEEEEEEQEEKSCVEENKGPEEKQDEERSRSSYPAQRLPDFGMTI
What are the official names of this protein?
Glutamate-rich protein 4.
Protein: CLPP_FRATM
Sequence: MITNNLVPTVIEKTAGGERAFDIYSRLLKERIVFLNGEVNDHSANLVIAQLLFLESEDPDKDIYFYINSPGGMVTAGMGVYDTMQFIKPDVSTICIGLAASMGSLLLAGGAKGKRYSLPSSQIMIHQPLGGFRGQASDIEIHAKNILRIKDRLNKVLAHHTGQDLETIVKDTDRDNFMMADEAKAYGLIDHVIESREAIIK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SDA1_DANRE
Sequence: MSGRHNNKLPTNLPQLQNLIKRDPKSYTEEFLQQYRHYQSNVEIFKHQPDKANKDLSELVMFLAQVGHCYLEELSDFPQQLTDLLLNYHTVLESDLRMTFCKALIMLRNKDLVSPTSLLGLFFELLRCHDKLLRKTLYTHIVTDIKNINAKHKNNKMNTTLQNFMYTMLRDSNPIAAKISLDVMVELYRRNIWNDAKTVNVITTACFSKVTKILVAGLKFFLGKDEDEKKDDDSESEDEGSTARDLMMRYSTGKKTSKNKKKLEKAMKVLKKHKKKKKVEVFNFSAIHLIHDPQDFSEKLLKQLESSNERFEVKIMMMELISRLVGIHELFLFNFYPFVQRFLQPHQREVTKILLCAAQSSHQLVPPEIIEPVIMTIANNFVTDRNSGEVMTVGINAIKEVVARCPLSMSEDLLQDLTQYKSHKDKNVVMSARGLIQLFRDLNPKMLTRKDRGRPTESSKEAKIHKYGELEAKDYIPGAEVLEAEKAEDEEDEDGWESASMSDDDEDGEWVNVHHSSDDDQAEVAEKLQSIPEEERKAKAAMVSTSRLLTQDDFKKIRVAQMAKEVGNAPGKGQKRKNVDSDEEERGELLSLRDIERLHKKPKSDKETRLATAMAGRTDRKEFTKKRGKLNPYASTSNKEKKRKKNFMMMRHSQNVRTKGKRSFREKQIALRDSLLKKRKFK
What is the function of this protein?
Required for 60S pre-ribosomal subunits export to the cytoplasm.
What are the official names of this protein?
Protein SDA1 homolog, SDA1 domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the SDA1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RL18_UREPA
Sequence: MKRINFSRAKQRALRAKRLHVKIRNLQLAANKPVLVITKTNAHIWAQLICYNKNITLASSSSVQLDLQNGNKDNARLVGVDIAKKALAQGFKQVIFNKNGAKYHGRIKALADAAREAGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: YF64_SCHPO
Sequence: MFCYFLSKSYDDCSRYYIISNMAFYFPVYDSDSPTTVHHDERKESWRSHGFIVCLHIRCCICCKYNSKIKKPSLNIALRIQSLKIIKILIFQFYSTKPLWDKNSPEYKQLRSEIEATKRDEEVKNGELIDPNVTTEDEKL
What are the official names of this protein?
Putative uncharacterized protein C23C4.04c.
Protein: RL35_XYLFA
Sequence: MPKIKTNRAAAKRFRKTASGKYKAGHANRSHILTKKATKRKRNLRQQNHVRAEDAGRLDRMLPYL
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: PDXH2_RALSO
Sequence: MNATDMDTEAAFRNDHETIAGEDPFAMFGEWLELAHRKEINDANAMALATADPDGLPNVRMVLLKGFDREGFVFYTNTESQKGVELAENMQAAAVLHWKSLRRQVRFRGTVNRVSAEEADAYFVSRARASRIGAWASKQSRPLENRTALAKSVATEAARFGISDIPRPAFWTGFRIVPNCIEFWMDKPFRLHDRLVFKRSHSGEPWSALKLYP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase 2, PNP/PMP oxidase 2, PNPOx 2, Pyridoxal 5'-phosphate synthase 2.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: LIPB_XANAC
Sequence: MDAVAAEPVSSSMAGLPAQLRDLGQQDYAPVWRAMQRFTDAREEYTADEIWVVEHAPVFTLGQAGKPEHVLAPGEIPVLQVDRGGQVTYHGPGQLVVYPLLDLRRLKIGVRDYVCKIEQALIDTLDEWNIVAERRDGAPGVYVGGAKIAALGIRVRRGCTFHGLSFNVAMDLQPFHRINPCGYQGLQVTSVLDLGGPSGMDAVKAVLLDQLARQFGLVLQPTSALPDLSLPA
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCD_SALA4
Sequence: MRLCDRDIEAWLDEGRLSITPRPPVERINGATVDVRLGNKFRTFRGHTAAFIDLSGPKDEVSAALDRVMSDEIVLPDGEAFYLHPGELALAVTFESVTLPPDLVGWLDGRSSLARLGLMVHVTAHRIDPGWSGCIVLEFYNSGKLPLALRPGMLIGALSFEPLSGPAARPYNRRQDAKYRDQQGAVASRIDKD
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: LOLA_PSE14
Sequence: MRLIRMLLATALTFSVMSAHADSKDVARLTQLLEKSQTLTARFSQLTLDGGGTQLQETTGEMTLQRPGLFNWHTDAPQEQLMVSDGKKVSLWDPDLEQVTIKKLDQRLTQTPALLLSGDVSKISESFDITAKEAGGVIDFVLKPKTKDTLFDSLRLSFRNGIINDMQLIDSVGQRTNILFTGVKANEPVAASKFQFQIPKGADVIQE
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: HEX2_ARTBC
Sequence: MRFAKALAITAVLLSGVVEATSDAVIEEALKAPTINPLPGPVTWYLHADEGRKYLAPFVSYHGPHKSGIRDAWERCYSTIRRLKWYPQALEGPIPKFDPFPDQSSKPKEKRQNAPPGAMIRRVRVKVKDVDAKLAHKVDESYSLTVSAKSEAIEIEAQTPWGARHAFTTLQQIVVYDEKSQRFYIERPFTISEGPLYPIRGILLDSGRNFISPSKIKEQLDAMALSKLNVLHWHITDTQSWPLQVNTYPQMTEDAYSKRMVYSHATIKEIIEYARQRGIRVIPEIDTPSHSSSGWKRIDPDLVACGNSWWSNDFFPHHTALEPNPGQLDIAYNKTYEVLENLYKEVSSLFEDEFHHLGGDELQPNCYKFSKHVTKWLAEHPDMTLNDLLQEYVDRTLPALDKIKHRRFIYWEDMLLSEQIHAERIPRNVVLQTWNGGLDNIKKLTSNGYDVIVSSADFFYLDCGNGGWVSNDPRYNVMRNPTPGTPNFNYGGDGGSWCAPYKTWQRIYDYDFASELTGPEKEHILGGIAPLWSEQIDDANITPKFWPRAAALAELLWSGNRDKEGKKRTYLMTARINNFREYLTANGIGAAPLQPRYCLKHPHHCDLYSDPNAVLG
What is the function of this protein?
Beta-hexosaminidase that shows a broad substrate specificity.
What are the official names of this protein?
Probable beta-hexosaminidase ARB_01353, Allergen Pen c 20 homolog, Beta-GlcNAcase, Beta-N-acetylhexosaminidase, N-acetyl-beta-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 20 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SMTN_MOUSE
Sequence: MADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQELEREEEALASKRFRAERQDNKENWLHSQQREAEQQAALARLAGRLESMNDVEELTTLLRSAGEYEERKLIRAAIRRVRAQEIKAATLAGRLCSRLPSSGPREDSRRQAAHTLDPGKVPEPEQQEQQTEVLEPTPTPEDTSQDVTTVTLLLRAPPGGRPSSPASPHNSPTSASPEPLLEPAGAQCPAVEAPVSSEPLPHPSEAPSPEPPMSPVPSSSRGRVISKPLPGPTEPSDTLDSIRGFSNTKRADPSETKSCQRSLSVLSPRQPTPNREPTSLAGPSQFRRVGSVRDRVQKFTSDSPVVARLQDGPPRTALASPTPTRLPGPSLISTTPASSSSSNSSSPSPSDTSSHKKQRELAHSLAELQSCPQEEGPGGRGLALRSLENRAGGPKPCSEEPSTPPPVAVGTGEPGGSMKTTFTIEIKDGRGQASTGRVLLPTGNQRAELTLGLRAPPTLLSTSSGGKNTITHISNPGTVTRLGSVTHVTTFSHASPGNRGGCNFKMEPDPAEPPSTTVEAANGAEQARVDKGPEGRSPLSAEELTAIEDEGVLDKMLDQTTNFEERKLIRAALRELRQRKRDQRDKERERRLREARARPGESRSNVATETTTRHSQRAADGSTVGTVTKTERLVHSNDGTQTARTTTVESSFMRRLENGSSSSSTTTTTVQTKSFSSSSSSSSSKKMGSIFDREDQTSSRPGSLAALERRQAEKKKELMKAQSLPKTSASQARKAMIEKLEKEGSAGGPGTPRTAVQRSTSFGVPNANSIKQMLLDWCRAKTRGYEHVDIQNFSSSWSDGMAFCALVHNFFPEAFDYGQLSPQNRRQNFEMAFSSAEMLVDCVPLVEVEDMMIMGKKPDPKCVFTYVQSLYNHLRRHELRLRGKNV
What is the function of this protein?
Structural protein of the cytoskeleton.
What are the official names of this protein?
Smoothelin.
What is the protein family that this protein belongs to?
Belongs to the smoothelin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Exhibits a filamentous organization.
Protein: RS8_STAAC
Sequence: MTMTDPIADMLTRVRNANMVRHEKLELPASNIKKEIAEILKSEGFIKNVEYVEDDKQGVLRLFLKYGQNDERVITGLKRISKPGLRVYAKASEMPKVLNGLGIALVSTSEGVITDKEARKRNVGGEIIAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: UBIE_BRUME
Sequence: MSQQNGNVNRVGAQDRVGASGGMEHSFGFKAVDENEKQGLVNDVFHKVAKRYDIMNDLMSAGMHRVWKDAMVAWLAPSKRPGWTSLDVAGGTGDIAFRIVEASGRQAHVTILDINGSMLGVGRERAIKKGLIDNLEFVEANAEELPFEDNSFDAYTIAFGIRNVPHIDKALSEAYRVLKPGGRFLCLEFSEVELPVLDKVYDEWSFRAIPRIGKMITGDADSYSYLVESIRKFPKQQDFAAMIEKAGFERVSYRNFTGGIAALHSGWKL
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: TSAD_IDILO
Sequence: MRVLGIETSCDETGVAVYDTEKGLLAHQLYSQVKLHADYGGVVPELASRDHVRKTLPLIKAALKEAGISHQQLDGIAYTMGPGLVGALLVGACIGRSLAFGWNLPAVGVHHMEGHLLAPMLEENQPEFPFVALLVSGGHTQLVQVKGIGDYHLLGESVDDAAGEAFDKTAKLMGLDYPGGPRLAALAEQGNSDRFTFPRPMTDRPGLNFSFSGLKTSAANTLAANDSDEQTLADIARAFEDAVVDTLVIKCRRALKETGYKRLVVAGGVSANKHLRAKLEALLEKQKGQIFYPRTEFCTDNGAMIALAGALRLEAGEREPLAVKTHPRWPMTDLKPMVNISDAV
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCD_CAMC1
Sequence: MGLKSDSWIRKMSVEKKMIVPFAEEQVGRGVVSYGVSSYGYDIRVGDEFKIFTNIGGTVVDPKNFDEKNVVDFKGDVCIVPPNSFALARTIEYFNMPDNVLAICLGKSTYARCGIIVNVTPFEPGFKGHITIEISNTTPLPAKIYANEGIAQVLFIEGDEPCEVTYADKNGKYQAQEGITLPRILK
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: RK19_CHLVU
Sequence: MAKLQQLVQAIQSGTIKTELPDVRVGDLVRIGVSIQEGNKQRIQPFEGTVISKHQAGANSTVTVRKSLQGIGVERVFPLYAPCVANLQVLRRAQVSRAKLYYLRSRTGKATRLKEKFETLPQIWMNQNQH
What are the official names of this protein?
50S ribosomal protein L19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: COBT_SALDC
Sequence: MQTLHALLRDIPAPDAEAMARAQQHIDGLLKPPGSLGRLETLAVQLAGMPGLNGTPQVGEKAVLVMCADHGVWDEGVAVSPKIVTAIQAANMTRGTTGVCVLAAQAGAKVHVIDVGIDAEPIPGVVNMRVARGCGNIAVGPAMSRLQAEALLLEVSRYTCDLAQRGVTLFGVGELGMANTTPAAAMVSVFTGSDAKEVVGIGANLPPSRIDNKVDVVRRAIAINQPNPRDGIDVLSKVGGFDLVGMTGVMLGAARCGLPVLLDGFLSYSAALAACQIAPAVRPYLIPSHFSAEKGARIALAHLSMEPYLHMAMRLGEGSGAALAMPIVEAACAMFHNMGELAASNIVLPEGNANAT
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: KDSB_RHIL3
Sequence: MSDSNLDGVLVLIPARMASTRLPGKPLADICGLPMIVQVAMRAREAAIGRVVVAVDETRVFDAVAAAGFEVVMTRVDHQSGSDRIFEALTKVDPEGKAKIIVNIQGDLPTIDPETVRAALRPLENEAVDIGTLTTEIDNEEDKTAPHIVKIIGSPISGNRLHALYFTRATAPYGQGPLYHHIGLYAYRRAALERFVSLGPSTLEKRESLEQLRALEAGMRIDAEVVDTVPLGVDTPADLEKARRILSAKSN
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIHI_SHEON
Sequence: MSRSKKTRKGGENSPKQQPRVKKQDRAEVTGKRAEKGNKSGSRHNEALIQAQAPQKKAAQKKDPRHGSKKPVALALPTTTEKSATPKVKQPKLTDEQKLLKLEEDPRLNQLLDMLEEGRNLSDADQKWLDQQLNKIEALMIKLGISDELEDEAPAKSKADSDDDLFDRFESGAELLKDYQDKF
What is the function of this protein?
A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function.  May play a role in ribosome biogenesis.
What are the official names of this protein?
Der GTPase-activating protein YihI.
What is the protein family that this protein belongs to?
Belongs to the YihI family.
Protein: RL37A_CRYST
Sequence: MAKRTKKVGIVGKYGTRYGASLRKTVKKMEITQHSKYTCQFCGKDAMKRQAVGIWGCKSCRKVVAGGAWVYSTMAAVTVRSAVRRLREMKES
What are the official names of this protein?
60S ribosomal protein L37a.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL43 family.
Protein: PANB_MYCTO
Sequence: MSEQTIYGANTPGGSGPRTKIRTHHLQRWKADGHKWAMLTAYDYSTARIFDEAGIPVLLVGDSAANVVYGYDTTVPISIDELIPLVRGVVRGAPHALVVADLPFGSYEAGPTAALAAATRFLKDGGAHAVKLEGGERVAEQIACLTAAGIPVMAHIGFTPQSVNTLGGFRVQGRGDAAEQTIADAIAVAEAGAFAVVMEMVPAELATQITGKLTIPTVGIGAGPNCDGQVLVWQDMAGFSGAKTARFVKRYADVGGELRRAAMQYAQEVAGGVFPADEHSF
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPLN1_BOVIN
Sequence: MKSLLLLVLISFCWADHHSDNYTVDHDRVIHIQAENGPRLLVEAEQAKVFSRRGGNVTLPCKFYRDPTAFGSGTHKIRIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYHGRVFLKGGSDNDASLVITDLTLEDYGRYKCEVIEGLEDDTAVVALDLQGVVFPYFPRLGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRSGLDWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKLLGYDRCDAGWLADGSVRYPISRPRRRCSPSEAAVRFVGFPDKKHKLYGVYCFRAYN
What is the function of this protein?
Stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix.
What are the official names of this protein?
Hyaluronan and proteoglycan link protein 1, Cartilage-linking protein 1, Cartilage-link protein, Proteoglycan link protein.
What is the protein family that this protein belongs to?
Belongs to the HAPLN family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.