PharMolix/UniProtQA huggingface dataset:
Protein: RUVB_CYAP4
Sequence: MAILSSQKQPLEPEPSKNPQSVQQPGLPPSTPEQGLLTAEVSPEERLSRTDDIRPQRLADYVGQKELKEVLQIAIQAAQSRREPLDHLLLYGPPGLGKTTISLILAAEMGVSCKVTSAPALERPRDIVGLLVNLKPGDVLFIDEIHRLARMTEELLYPAMEDFRLDITIGKGQSARTRSLPLPPFTLVGATTRVGSLTSPLRDRFGLIQRLRFYEPEELSQIILRTASLLKTELTPSAALEIARRSRGTPRIANRLLKRVRDFAEVKAAGTITETIASEALQLFNVDPCGLDWTDRRLLTVMIEHYGGGPVGLETIAAATGEEAQTIEEVYEPYLLQIGYLNRTPRGRVATLAAWKHLGYTPPDGQLSLL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: RR4_PILTE
Sequence: RFKKIRRLGALPGLTSKRPRSGSDLKNQLRSGKRSQYRIRLEEKQKLRFHYGLTERQLLKYVHIAGKAKGSTGQILLQLLEMRLDNILFRLGMASTIPGARQLVNHRHILVNGRIVDIPSYRCKPRDIITTKNKQRSKALIQNFIASYPHQEELPNHLTIDPFQYKGLVNQIIDSKWIGLKINELLVVEYYSRQT
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PQQE_PSE14
Sequence: MSDIAPVTNTPYIPPTPEVGLPLWLLAELTYRCPLQCPYCSNPLDFAKQGQELTTEQWFKVMQEAREMGAAQIGFSGGEPLVRQDLAELIAEARRLGFYTNLITSGIGLTKEKIIAFKEAGLDHIQISFQASDEQVNNMLAGSKKAFAQKLEMAKAVKKHGYPMVLNFVTHRHNIDRIDKIIELCLALEADFVELATCQFYGWAHLNRLGLLPTKDQLVRAEAVTNEYRVRLEAENHPCKLIFVTPDYYEERPKACMNGWGNIFLTVTPDGTALPCHGARQMPIQFPNVRDYSMQHIWYDSFGFNRFRGYDWMPEPCRSCDEKEKDFGGCRCQAFMLTGDAANADPVCSKSYHHGIITQARDESETATQTIEELAFRNDRNSRLIAKSS
What is the function of this protein?
Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
What are the official names of this protein?
PqqA peptide cyclase, Coenzyme PQQ synthesis protein E, Pyrroloquinoline quinone biosynthesis protein E.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. PqqE family.
Protein: RIMM_PSELT
Sequence: MSDYVVIGKITKTHGLFGSVKVLPLTNALEVFQKLENVFIKNDAQSNTHRLQIEEIRKAGKGFLIKFSGIDDEERARKIVGLSLAVRVTDLPKPKSPNEYYYYELLNVEVLDQSGNFIGRVEDIIQTGSNEVAVVKNGSFEMLIPVIHDYIIKFEKRKRLVVKVPEWI
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATRX_TRTV
Sequence: MESYIIDTYQGVPYTAAVQVDLIEKDSNPATLTVWFPLFQSSTPAPVLLDQLKTLSITTQYTASPEGPVLQVNAAAQGAAMSALPKKFAVSAAVALDEYSRLEFGTLTVCDVRSIYLTTLKPYGMVSKIMTDVRSVGRKTHDLIALCDFIDIEKGVPITIPAYIKAVSIKDSESATVEAAISGEADQAITQARIAPYAGLILIMTMNNPKGIFKKLGAGMQVIVELGPYVQAESLGKICKTWNHQRTRYVLRSR
What is the function of this protein?
Plays a crucial role in virus assembly into filaments and budding.  Early in infection, localizes in the nucleus where it may inhibit host cell transcription.  Later in infection, traffics to the cytoplasm to associate with inclusion bodies, the site of viral transcription and replication.  During virus assembly and budding, acts as a bridge between the nucleocapsid and the lipid bilayer.
What are the official names of this protein?
Matrix protein, M protein.
What is the protein family that this protein belongs to?
Belongs to the pneumovirinae M protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Host nucleus. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=In the cytoplasm, associates with inclusion bodies. During bud formation, associates at the inner side of the plasma membrane of infected cells.
Protein: RBFA_BRUAB
Sequence: MARSHDTKGSGGLSQRQLRVGEQVRHALAQVLQRGEIRDDLIERTVISVSEVRMSPDLKIATCFITPLGSADPQAVIKALASHAKFIRGRVAPSLAQMKYMPEFRFRPDTSFDNFSKIDALLRSPEVARDLSHDDDEDGGADEAPRNGDE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZUP1_RAT
Sequence: MLSCDICGETVTSEPDRKAHLIVHMENEIICPFCKLSGINYNEMCFHIETAHFEQTTPEKSFETLAAVQYENSDLGNTKLHSTVEVTSGIHSACASNFPKESSESLSKDRTLKQEAFYTESVAESRKYQKSREKQSGLSEAQGSIYETTYSPPECPFCGRIERYSQDMEIHVKTKHASLLESPLEDCHQPLYDCPMCGLVCTNYHILQEHVDLHLEESSFQQGMDRVQCSSDRELAHQLQQEEERKRKSEESRQEREEFQKLQRQYGLDNSGGYKQQQLRHMELEVTRGRMHPSEFHSRKADMLESIAVGIDDGKTKTSGIIEALHRYYQNIATDVRCVWLSTVVDHFHSSFGDKGWGCGYRNFQMLLSSLLQNEVYSDCLKGMSVPCIPKIQSMIEDAWNEGFDPQGASQLNNKLQGTKAWIGACEIYTLLTSLKVKCRIIDFHKSTGPSGTHPRLFEWILNYYSSETEGAPKVVCTSKPPVYLQHQGHSRTVVGIEERKNRTLCLLIFDPGCPSREMQKLLKQDMEAGSLRQLRKCVGNLKHKQYQIVAVEGILSPEERAARKQASQVFTAEKIP
What is the function of this protein?
Deubiquitinase with endodeubiquitinase activity that specifically interacts with and cleaves 'Lys-63'-linked long polyubiquitin chains.  Shows only weak activity against 'Lys-11' and 'Lys-48'-linked chains.  Plays an important role in genome stability pathways, functioning to prevent spontaneous DNA damage and also promote cellular survival in response to exogenous DNA damage.  Modulates the ubiquitination status of replication protein A (RPA) complex proteins in response to replication stress.
What are the official names of this protein?
Zinc finger-containing ubiquitin peptidase 1, Lys-63-specific deubiquitinase ZUFSP, DUB, Zinc finger with UFM1-specific peptidase domain protein.
What is the protein family that this protein belongs to?
Belongs to the peptidase C78 family. ZUFSP subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Mostly present in the nuclear fraction. Localizes to DNA lesions.
Protein: SELA_PSEA7
Sequence: MSSVRLPSVDRLLRSAAAAPLHQRYGREALLATLRDLLDELREPARQGALAAIELSEAVLAGRAGERLAAQHASRVRRVFNLTGTVLHTNLGRALLPEEAIEAITLAARYPLNLEFDLASGKRGDRDDLITGLIRELTGAEAVTVVNNNAAAVLLALNSLGARKEGIISRGELIEIGGAFRIPDIMTRAGVRLHEVGTTNRTHARDYEAAIGPRSGLLMRVHTSNYSVQGFTASVPTAQLAAIAHGHGLPLLEDLGSGTLVDLTRWGLPKEPTVQEALADGADIVTFSGDKLLGGPQAGLILGNRELVGRIKKNPLKRALRVDKLTLAALEAVLGLYRDPDRLAERLTTLRLLSRPAVEIRAQAERLAPALAEALGEDWEVAVVDALGMIGSGAQPVARLASAALCLRPRQPRRLRGRTLRNLEEALRGLPLPVIGRLDDDALWLDLRQLDDEPAFRAQLPRLRGELS
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRE1_SERP5
Sequence: MSELSAARELDEIAHTASEGWMIAGLIGGAIVGAALIAVTGGTAAVAVAAVVAGASAGGGLGEVLGSMSWAPRHVTGVLADGSPNVYINGRPAIRAHISTGECSEDGPAKKVVAQGSAKVYINDFPAARINDLLACSAEIHTGSPNVIIGGEKEQTDDIEPEIPDWVNWTLLAAGAGAAAVLATPAIAILGTLGGLGGGFAGSLIGGAFFGEGSDGQKWSMLAGGFVGGFAGGKGGAKFDAWRNTKIVEPPPRVTTKVDPISPPRMTLAEAVGQEQAKVWTQTARANAEKNNAQLSTLLTDDQIGAIYGYTTNEGYTALNPALRGQTPLTPELEAFTGHVTDGLNKLPAYNGETYRGTTLPAHILEQNQIGGTVSDGGFMSTSAKTPFDGDVSISVRGNSGKQIDFLSKYKNEAEVLYPPNTRFEVINRIEQNGTTHLLYREIP
What is the function of this protein?
Toxic component of a contact-dependent interbacterial competition system (also called effector-immunity systems).  Acts by ADP-ribosylating a number of target proteins in target cells; E. coli target proteins include FtsZ, EFTu, RNase E, Fis, RL9, SucB, and LolD.  FtsZ is thought to be the physiologically relevant target as it is ADP-ribosylated on a critical residue.  ADP-ribosylation of FtsZ prevents formation of the FtsZ mid-cell ring and inhibits cell division.  Overexpression of the whole Tre1 protein or the ART domain in E. coli is toxic; cells elongate dramatically and some undergo lysis.  Toxic activity is neutralized by coexpression of the cognate immunity protein Tri1-Sp; Tri1-Sp neutralizes this protein both by binding to and occluding the active site (via Tri1's N-terminal extension) and by hydrolysis of the ADP-ribosyl moiety from the target protein.  Tre1 can also be neutralized by non-cognate immunity protein Tri1-Pp from P. putida strain GB-1, with which it does not form a stable complex; DraG of R. palustris does not neutralize the toxic effects of this protein.  In interbacterial competition studies Tri1 from P. putida strain B6-2 also neutralizes this protein.
What are the official names of this protein?
NAD(+)--protein-arginine ADP-ribosyltransferase Tre1, Effector protein Tre1, Tre1-Sp, Type VI secretion ADP-ribosyltransferase effector 1.
What is the protein family that this protein belongs to?
Belongs to the Arg-specific ADP-ribosyltransferase family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Note=Probably delivered to target cells by a type 6 secretion system (T6SS).
Protein: IDI2_CLAXA
Sequence: MSLTSRLYKPRLFSLPSQHSFRALPILSPPLRSSCIPAPLSVRASLSTRSIATSIAMGEAAADAGMDAVQRRLMFDDECILVDEVDCVVGHESKYNCHLWEKIESGNMLHRAFTVFLFNSKFELLLQQRSATKVTFPLVWTNTCCSHPLYRESELIDENNLGVRNAAQRKLLDELGIPAEDVPVDEFTPVSRMLYKAPSDGKWGEHELDYLLFIVRDVGIHPNPDEVADIKYVNREQLKELLRKADAGEEGLKLSPWFRLVVDNFLPKWWDHVEKGTLSEAVDMKTIHNL
What is the function of this protein?
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate Delta-isomerase II, Isopentenyl pyrophosphate isomerase II, IPP isomerase II.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 1 family.
Protein: ORN_BURM7
Sequence: MTDISAVAGQPALVRNELNLVWLDMEMTGLDPDTDRIIEIAVVVTNSTLDIAVEGPVLAIHQSDETLAKMDDWNKNTHGRSGLIDRVRASSVTEADAAAQIAAFLAEHVPPGKSPMCGNSICQDRRFMARWMPELERFFHYRNLDVSTLKELCRRWQPAIYKGFQKRAMHTALADIHESIDELKYYRERFLIPAAPAGETA
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCUP_ACIBY
Sequence: MTTLKNDRFLRALLREPVDTTPIWMMRQAGRYLPEYRETRSKAGDFLSLCKNTEFACEVTLQPLRRYDLDAAILFSDILTIPDALGLGLYFETGEGPKFHKTVRTEQDVANLPKLNAKADLDYVMNAVSTIRSALGGQVPLIGFSGSPWTLATYMVEGGSSKEFRFTKQMMYAQPEVLHALLDHLADSVIDYLNAQIDAGAQAIQIFDSWGGALAHREYVEFSLNYMKKIIAGLQREKDGRRIPVIVFTKGGGQWLEPMITTGADALGLDWTTPLNTARTTVAGRVALQGNLDPAVLYGSAASIEKAVKAMLDDAYANGEKTGYVANLGHGITQWVDPAQPKIFVDTVHEYSAKYLG
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAP1L_HUMAN
Sequence: MNASGSGYPLASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDTMNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFGNILSCKVACDEHGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRREREAELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSRCFGFVNFEKHEEAQKAVVHMNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDKLRKEFSPYGVITSAKVMTEGGHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALAQRKEERKAILTNQYMQRLSTMRTLSNPLLGSFQQPSSYFLPAMPQPPAQAAYYGCGPVTPTQPAPRWTSQPPRPSCASMVRPPVVPRRPPAHISSVRQASTQVPRTVPHTQRVANIGTQTTGPSGVGCCTPGRPLLPCKCSSAAHSTYRVQEPAVHIPGQEPLTASMLAAAPLHEQKQMIGERLYPLIHDVHTQLAGKITGMLLEIDNSELLLMLESPESLHAKIDEAVAVLQAHQAMEQPKAYMH
What are the official names of this protein?
Polyadenylate-binding protein 1-like.
What is the protein family that this protein belongs to?
Belongs to the polyadenylate-binding protein type-1 family.
Protein: RL37_THEGJ
Sequence: MGAGTAPKGKRNRTPTHIRCRRCGRRAFNVKKGYCAACGFGRSRRMRKYSWSHKWKKKRNLSY
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L37e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL37 family.
Protein: PFKA_TRIV2
Sequence: MRKKIGILTSGGDCPGLNCVIRAVVSHATLTYDWEVFGIPYATQGLLERQAIALNMHGWDLRGIDPLLNMGGTILGTINKGDTLAHVDEMLASYEALALDALIVIGGDGSLGILHELASRGNWNLVAIPKTIDSDVALTERAVGFDTAVNTIVDALNRLTFTAASHDRVMIVEVMGRSAGHLALHAGIAGGADVILIPEISYTISGLCQYIAELRDRWQRKFAIVVVAEGAKLCLEDVQENIASACVSPKCGRGQYIAEQIARCSKNLIDTRVSVLGHIQRGGIPSALDRLTATVFGKTAVDLVAQGKFGQMVAWQNGEAIPVPIQDVVAQSPLHVNPQGSLVQSARCLGIYVGEKT
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMR1A_XENLA
Sequence: MEELAVEVRGSNGAFYKAFMKDVHEDSITVTFENNWQQERQIPFHDVRFPPPSGYNKDINERDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKPATKSSFHKVKLDVPEDLRQMCAKDSAHKDFKKAVGAFSVSYDSENYQLVILSVNEVSIKRASMLSDMHFRSLRTKLSLMLRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGANIQQARKVPGVTAIDLDEDTCTFHIYGEDQEAVKKARTYLEFAENVIQVPRNLVGKVIGKNGKLIQEIVDKSGVVRVRIEAENDKNISQEEGIVPFVFVGTKDSITNATVLLDYHLNYLKEVDQLRLERLQIDEQLRHIGASSRPPPNRPDKEKGYLSEDCSGTVRGSRPYSNRGRSRRGTGYASGTNSEASNASETESDHRDELSDWSLAPAEDDRDNYHRRGDGRRRGGTRGQGMRGRGGFKGNDDQPRPDNRQRNSRETKARTSDGSLQIRLDCNNERSVHTKTLQNASVDGSRLRTGKDRVQKKEKTDGVDGPQVVVNGVP
What is the function of this protein?
Multifunctional polyribosome-associated RNA-binding protein that plays a central role in neuronal development and synaptic plasticity through the regulation of alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of target mRNAs (By similarity).  Acts as an mRNA regulator by mediating formation of some phase-separated membraneless compartment: undergoes liquid-liquid phase separation upon binding to target mRNAs, leading to assemble mRNAs into cytoplasmic ribonucleoprotein granules that concentrate mRNAs with associated regulatory factors (By similarity).  Binds poly(G) and poly(U), and to a lower extent poly(A) and poly(C) (PubMed:7781595).
What are the official names of this protein?
Fragile X messenger ribonucleoprotein 1 homolog A, xFMR1-A.
What is the protein family that this protein belongs to?
Belongs to the FMR1 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Chromosome, centromere. Chromosome. Cytoplasm, perinuclear region. Cytoplasm, Cytoplasmic ribonucleoprotein granule. Cytoplasm, Stress granule. Perikaryon. Cell projection, neuron projection. Cell projection, axon. Cell projection, dendrite. Cell projection, dendritic spine. Synapse, synaptosome. Cell projection, growth cone. Cell projection, filopodium tip. Synapse. Postsynaptic cell membrane. Presynaptic cell membrane. Cell membrane.
Protein: Y1510_MYCTO
Sequence: MYERRHERGMCDRAVEMTDVGATAAPTGPIARGSVARVGAATALAVACVYTVIYLAARDLPPACFSIFAVFWGALGIATGATHGLLQETTREVRWVRSTQIVAGHRTHPLRVAGMIGTVAAVVIAGSSPLWSRQLFVEGRWLSVGLLSVGVAGFCAQATLLGALAGVDRWTQYGSLMVTDAVIRLAVAAAAVVIGWGLAGYLWAATAGAVAWLLMLMASPTARSAASLLTPGGIATFVRGAAHSITAAGASAILVMGFPVLLKVTSDQLGAKGGAVILAVTLTRAPLLVPLSAMQGNLIAHFVDRRTQRLRALIAPALVVGGIGAVGMLAAGLTGPWLLRVGFGPDYQTGGALLAWLTAAAVAIAMLTLTGAAAVAAALHRAYLLGWVSATVASTLLLLLPMPLETRTVIALLFGPTVGIAIHVAALARRPD
What are the official names of this protein?
Uncharacterized protein MT1558/MT1560.
What is the protein family that this protein belongs to?
To M.tuberculosis Rv3630 and M.bovis Mb3654.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ABCG7_DICDI
Sequence: MEVISINNTNCNNINNNIDNTNIDTNSIHNKNNIDNNIDNNNIDNNSIGNNNNNIDNNNNNIANNNINNINNIDNNIDNNNNIDNNNNKNNSNNYNNIDNNNNNNNNNNNNNNNNNNIDNYNLVNNNNNNNNNSEISTPNFPYNNNNLTNLNSDNNIGVQVIFENISYKTENRNYKKQIKDEKKRKKKLEMERSNSSNSNSSYDVESSASGLQTPQQSRSSILPTNSLNISKIDQSMNPQQTRSTTNGKIEKEITILSNVSGIIEKSEMVGLFGPSGSGKSTLLDILANRKSTGTISGKILVNGKEIGDAYKKYCSYVTQDEILLQTSTVEETLKFHADLRLPGLSDQDKWKVVEQVIKDIGLTKKSKSKIGGILPGGMIVKGLSGGEKKRVSIGCALVTNPSLLFLDEPTSGLDSLNALKVMKVLMNLTVIKGVTVICSIHQPRPEIYHLFNKIMIMLKGRMIYCGNDVLNYLSSLPNQYQCPNYTNPADFILDTCHEISECDHYEEICESWETNWRDNMLAVSRIQPFNRSIEPNKSCSLLYQYKILLNRNFKDFFRNSTQYITRLSGGFMIGLLFSACFGTLSPSQEDVLKISGILFFLIAVLNLIPFTCITLFLSNREVFNSERASKIYHSLPFYLSTITTEAFIQFLVSLIVSLLVYTINHLRWNFSSFFITYFILYLINLLSDLYIIAISNITGKSDLTFIYGTTISITFLLFMGHLVPVKQLPKSFGWIHWLNPLYYGYATVMVAQFKDYPLECPNDFCQFPNGNDVLKFYNLEDWTLQKGIGIIILWICFFFVSGYWAISKLNKEKR
What are the official names of this protein?
ABC transporter G family member 7, ABC transporter ABCG.7.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: LOLA4_DROME
Sequence: MDDDQQFCLRWNNHQSTLISVFDTLLENETLVDCTLAAEGKFLKAHKVVLSACSPYFATLLQEQYDKHPIFILKDVKYQELRAMMDYMYRGEVNISQDQLAALLKAAESLQIKGLSDNRTGGGVAPKPESSGHHRGGKLSGAYTLEQTKRARLATGGAMDTSGDVSGSREGSSSPSRRRRKVRRRSMENDAHDNSNSSVLQAAASNQSILQQTGAGLAVSALVTTQLSSGPAAGTSSQASSTQQQQPLTSTNVTKKTESAKLTSSTAAPASGASASAAVQQAHLHQQQAQTTSDAINTENVQAQSQGGAQGVQGDDEDIDEGSAVGGPNSATGPNPASASASAVHAGVVVKQLASVVDKSSSNHKHKIKDNSVSSVGSEMVIEPKAEYDDDAHDENVEDLTLDEEDMTMEELDQTAGTSQGGEGSSQTYATWQHDRSQDELGLMAQDAQQRDPQASKQDKGEQTEGAQDEFELDDCLLESNDIVITQNKDGFVLHVKKLGNITAAKLEENQAVAQQQGQAAVTVTGPAGQPTPTITELLNAAAASHSEPKPTLTTLTSTPIKLPSSECELINIKKIIPATTTIATHHPHTSSTIIHPHHIIQHVSQEPHHQEHHQQHQTIHIEEVPQTSQQHHQQQHHHQLQTVQPTHTQVQSIITAHPGQTINLVGLRNVQLADSKPIASRIRYSRGKIIGPTVQNLQIVETHEPIQHQHHELSDGTKYEISEIDLNNPNASAAIISDLVKYAEIDDIELPDGTKIGIGFAPSEITEHMQTSGGETHITTIEHEPQELQTVHQHEQTQQTHHIHAGQLQTHHIQTVVQSSSGQQQHDQQQHHQHHSIELQDDDGVETITPEELGMHDSSKSYTILTTRPMKEESEHDPSGMTYELSLSDSSLGPCDDPESRYVCRHCGKKYRWKSTLRRHENVECGGKEPCHPCPYCSYKAKQRGNLGVHVRKHHPEKPQLESKRGRKV
What is the function of this protein?
Putative transcription factor required for axon growth and guidance in the central and peripheral nervous systems.  Repels CNS axons away from the midline by promoting the expression of the midline repellent sli and its receptor robo.
What are the official names of this protein?
Longitudinals lacking protein, isoforms F/I/K/T.
What are the subcellular locations of this protein?
Nucleus.
Protein: TNNI2_RABIT
Sequence: MGDEEKRNRAITARRQHLKSVMLQIAATELEKEEGRREAEKQNYLAEHCPPLSLPGSMAEVQELCKQLHAKIDAAEEEKYDMEIKVQKSSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAMLKALLGSKHKVCMDLRANLKQVKKEDTEKERDLRDVGDWRKNIEEKSGMEGRKKMFESES
What is the function of this protein?
Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
What are the official names of this protein?
Troponin I, fast skeletal muscle, Troponin I, fast-twitch isoform.
What is the protein family that this protein belongs to?
Belongs to the troponin I family.
Protein: BCHZ_ERYLO
Sequence: MTLVLDHDRAGGYWGATYVFTAVKGLQVIIDGPVGCENLPVTSVLHYTDALPPHELPIVVTGLGEEELGKTGTEAAMKRAWQTLDPELPAVVVTGSISEMIGGGVTPEGTNIKRFLPRTIDEDQWQSADRALTWLWTEFGPKKMPQPRPRKEGEKPVVNIIGPSYGMFNMPSDLAEIRRLVEGIGAEVGVVFPLGCHLADIRKLGTADANVCMYREFGRNLCETLERPYFQAPVGLSSTTKFLRALAAELGLDPEPFIEREKHTTIKPLWDLWRSVTQDFFATANFGIVANDTYARGIRHFLEDDMGLPCAFAYSREAGVKPRNDEVREDIHKSPPLVMFGSYNERMYMAEVGARGKFIPASFPGAAIRRHIGTPFMGYSGATYLVQEVCNALFDALFHILPLGTDMDKGQATLARGADVPVKAGSNGAPTHEVTWDTEAKARLDELVEEQPVLIRISAAKRLRDAAEAAARAKGADTVTKDCLQEALLEGEAV
What is the function of this protein?
Converts chlorophylls (Chl) into bacteriochlorophylls (BChl) by reducing ring B of the tetrapyrrole.
What are the official names of this protein?
Chlorophyllide reductase subunit Z, Chlorin reductase subunit Z.
What is the protein family that this protein belongs to?
Belongs to the ChlB/BchB/BchZ family.
Protein: TGT_CAMFF
Sequence: MNFKIDKTDGNARACTLQTAHSTIQTPIFMPVGTLGAVKSLDAIDLKEILDAKIILANTYHLYLRPTSKVVREFGGLHGFSKFDRSFLTDSGGFQAFSLSKISKPDENGIKFKSHIDGSMHYFTPKSVLDTQYDLSSDIMMILDDLVALPATKERIDLSIKRTINWAKIACEYHKSNKQKSVGIDQNIFGIIQGGTDYNARKLCAEALCEMEFDGLAIGGLSVGESNEEMYDTVEALMPFIDKNRPRYLMGVGTPEDLVQNVERGVDMFDCVMPTRNARNGTLFTSFGKINIKSAAFIKDDNKIDPECDCYTCSNFSRGYLNHLYKARELTFFRLASLHNLHYYLNLVKQMREAIMQGKFKEFKREFYAKRGMI
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: CATE_BACSU
Sequence: MSDDQNKRVNEHSKDEQLEQYRTDNSGKKMTTNQGLRVSEDEHSLKAGVRGPTLMEDFHFREKMTHFDHERIPERVVHARGFGVHGFFQVYEPMTEYTRAKFLQDPSVKTPVFVRFSTVAGSKGSADTVRDARGFATKFYTEEGNYDLVGNNIPVFFIQDAIKFPDLVHAFKPEPHNEMPQAATAHDTFWDFVANNPESAHMVMWTMSDRGIPRSYRMMEGFGVHTFRFVNEQGKARFVKFHWKPVLGVHSLVWDEAQKIAGKDPDFHRRDLWETIENGGKVEYELGVQMIDEEDEFKFDFDILDPTKLWPEELVPVKIIGKMTLNRNQDNVFAETEQVAFHPGNVVPGIDFTNDPLLQGRLFSYTDTQLIRLGGPNFHEIPINRPVCPFHNNQYDGYHRMTINKGPVAYHKNSLQNNDPSPATAEEGGYVHYQEKVEGKKIRQRSDSFNDYYSQAKLFWNSMSPVEKQHIISAFCFEVGKVKSKDVQRQVVDVFSNVDADLAEEIAKGVGVAAPAKRKASKEILTSPALSQARTVKTASTRKVAVLAGNGFHEKELQTVLEALKQEGITVDIISQNLGYMTSGSGQQLEASGTFLTVDSVLYDAVYAAGGLELKDNKQAMAFIREAYNHYKAIGAANEGIDLLQSSVGTTEGLGIVTAKDEPDYTAFSKAFIDAVAAHRHWDRRI
What is the function of this protein?
Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.  Involved in sporulation.
What are the official names of this protein?
Catalase-2.
What is the protein family that this protein belongs to?
Belongs to the catalase family. HPII subfamily.