PharMolix/UniProtQA huggingface dataset:
Protein: F16PC_STAHJ
Sequence: MTQTTESELREKYLDLLSQQFDSPEKLATEIVNLESILELPKGTEHFVSDLHGEYESFQHVLRNGSGNVRSKINDLYAKTLSQKEIDDLAALVYYPEEKLKLVKNNFDSKGKLNVWYITTIEQLIDLITYCSSKYTRSKLRKALPKEYTYIVEELLYKNNEFNNKKSYYETLVNQIIELEQSDDLIIGLSYSIQRLVVDHLHVVGDIYDRGPQPDKIMDTLINYHSVDIQWGNHDVLWIGAYAGSKACLANLLRICARYDNLDIIEDAYGINLRPLLTLAEEHYNGENPAFKPKKRPDKPVGLSKLEESQITKIHQAIAMIQFKLEMPIIKRRPTFEMEDRLVLEKVNYDTNEITIYGKTYPLKDTCFSTVDPQDPGKLLPEEEEVMNKLLLSFQQSEKLKRHMSFLMKKGKLYLPYNGNLLIHGCIPVDENGEMESFEIEGEQHKGRDLLDVFERHVRYAYDYKEITDDLSTDLVWYLWTGKYSSLFGKRAMTTFERYFIEDKASHKEPKNPYYYLREDVDMIRKMLKDFGLNPDEGRIINGHTPVKEIDGEDPIKADGKMLVIDGGFSKAYQKTTGIAGYTLLYNSFGMQLVAHQHFDSRDKVLSDGADELSVRRVVDEELQRKKIRDTNDGKVLQEQIRILKLLMHDRYLN
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 3, FBPase class 3, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 3 family.
Protein: PA1_VESGE
Sequence: GPKCPFNTDTVSMIIETRENRNRDLYTLQTLQNHPEFKEKTITRPVVFITHGFTSSASETNFINLSKALVDKDNYMVISIDWQTAACTNEAAGLKYLYYPTAASNTRLVGQYIATITQKLVKQYKISMANIRLIGHSLGAHVSGFAGKKVQELKLGKYSEIIGLDPAGPSFSSNKCSDRLCETDAEYVQILHTSNHLGTERILGTVDFYMNNGKNQPGCGRFFTEVCSHSRAVIYMAECIKHECCLIGIPKSKSSQPISSCTKQECVCVGLNAKKYPSRGSFYVPVESTAPFCNNKGKII
What is the function of this protein?
Catalyzes the hydrolysis of phosphatidylcholine with phospholipase A1 activity (By similarity).  May act as an allergen and induce hemolytic activity (By similarity).
What are the official names of this protein?
Phospholipase A1, PLA1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: CALX_HUMAN
Sequence: MEGKWLLCMLLVLGTAIVEAHDGHDDDVIDIEDDLDDVIEEVEDSKPDTTAPPSSPKVTYKAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVEEMKESKLPGDKGLVLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFHDKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKTHLYTLILNPDNSFEILVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPEAVKPDDWDEDAPAKIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPRCESAPGCGVWQRPVIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPDFFEDLEPFRMTPFSAIGLELWSMTSDIFFDNFIICADRRIVDDWANDGWGLKKAADGAAEPGVVGQMIEAAEERPWLWVVYILTVALPVFLVILFCCSGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRKPRRE
What is the function of this protein?
Calcium-binding protein that interacts with newly synthesized monoglucosylated glycoproteins in the endoplasmic reticulum.  It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits.  It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins.  Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation.  Additionally it may play a role in receptor-mediated endocytosis at the synapse.
What are the official names of this protein?
Calnexin, IP90, Major histocompatibility complex class I antigen-binding protein p88, p90.
What is the protein family that this protein belongs to?
Belongs to the calreticulin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endoplasmic reticulum. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545, PubMed:17081065). The palmitoylated form preferentially localizes to the perinuclear rough ER (PubMed:22314232).
Protein: NDUS4_DICDI
Sequence: MLKKFLISSIVKPTFQSRIIASTTLNGGAGRATFCSVNSINPNPTASQIKVDQEDLEVGEHLVIDDPNQQHIKSFLNGVEFNGKSVNIYRPSRNTMQTGTLRTKKWVIELPFNPKWNDRLMGWWASKDTLNQLNLRFNSETDAVAYCKEIGLNYNIVEEDVTLRKKKKYGHRFRYRGDLVGEKEREVGIN
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFS4 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: UVRC_UREU1
Sequence: MNDLLKTKLKLIPHKPGCYLWKDEFDQIIYIGKAKDLYNRTHSYFNGPKDNKTSKLVSNIKDLEYIVVNNVNEALILENNLIKTHRPKYNILLKDGSNYPYIMITNEQYPRLKYVRTYDKNKGIYFGPLADSTNKYQLFNLLNSIFPFNKCNHQPHQKCIYYDLHRCINQVQPQTYEKAIAEVKEIFKGNLDHILAILENKEQHAVAKLDFENAQKYAEQQKALTYIINSGLVQLDNNESFDVVGFYEKNNYLVIIIFNYVKGKLLNKSADTFAIYDHEINELITSFLMQYYSQNRISTKIIVSLDDDNLLALSQRFKTKFINAQTKFHKQILKLAFDNAILYFDSNIKSVINKQNELDEALNQLKQILKLPDLSMIECFDNSNINLSLPIAGMIVYQNGKLNNKLNRKYNLMTTKNASDYHFMIEVITRRYQRLVSQHQKLPNLIVVDGGKLQVNAALYALEQLQISIPLIGLKKDQKHKTNAIVLANGDEIILDRKSVLYKFLANMQNDVHNYAISFLRNKHTKSIFNSLLNDVQGLGKKRLNELLNYYDSINDLKSASDQELLQFLPKNVLVNLREKLNKI
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADH1_DROMO
Sequence: MAIANKNIIFVAGLGGIGFDTSREIVKKGPKNLVILDRIENPAAIAELKALNPKVTVTFYLYDVTVSVAESTKLLQKIFDQLKTVDLLINGAGILDDHQIERTIAVNFTGTVNTITAIMSFWDKRKGGPGGVIANVCSVTGFNAIYQVPVYSASKAAALSFTNSLAKLAPITGVTAYSINPGITKTPLLHKFNSWLDVEPRVGELLLEHPTQTSLECAQNFVKAIEANQNGAIWKVDLGTLEAIEWTKHWDSHI
What are the official names of this protein?
Alcohol dehydrogenase 1.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: SC5A5_RAT
Sequence: MEGAEAGARATFGAWDYGVFATMLLVSTGIGLWVGLARGGQRSADDFFTGGRQLAAVPVGLSLAASFMSAVQVLGVPAEAARYGLKFLWMCAGQLLNSLLTAFLFLPIFYRLGLTSTYQYLELRFSRAVRLCGTLQYLVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTLYTTVGGMKAVVWTDVFQVVVMLVGFWVILARGVILLGGPRNVLSLAQNHSRINLMDFDPDPRSRYTFWTFIVGGTLVWLSMYGVNQAQVQRYVACHTEGKAKLALLVNQLGLFLIVASAACCGIVMFVYYKDCDPLLTGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAVTVEDLIKPRMPGLAPRKLVFISKGLSFIYGSACLTVAALSSLLGGGVLQGSFTVMGVISGPLLGAFTLGMLLPACNTPGVLSGLAAGLAVSLWVAVGATLYPPGEQTMGVLPTSAAGCTNDSVLLGPPGATNASNGIPSSGMDTGRPALADTFYAISYLYYGALGTLTTMLCGALISYLTGPTKRSSLGPGLLWWDLARQTASVAPKEDTATLEESLVKGPEDIPAVTKKPPGLKPGAETHPLYLGHDVETNL
What is the function of this protein?
Sodium:iodide symporter that mediates the transport of iodide into the thyroid gland (PubMed:8559252, PubMed:9341168, PubMed:32084174).  Can also mediate the transport of chlorate, thiocynate, nitrate and selenocynate (PubMed:9341168).
What are the official names of this protein?
Sodium/iodide cotransporter, Na(+)/I(-) cotransporter, Sodium-iodide symporter, Na(+)/I(-) symporter, Solute carrier family 5 member 5.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: AKTIP_PONAB
Sequence: MNPFWSMSTSSVRKRSEGEEKTLTGDVKTSPPRTAPKKQLPSIPKNALPITKPTSPAPAAQSTNGTHASYGPFYLEYSLLAEFTLVVKQKLPGVYVQPSYRSALMWFGVIFIRHGLYQDGVFKFTVYIPDNYPDGDCPRLVFDIPVFHPLVDPTSGELDVKRAFAKWRRNHNHIWQVLMYARRVFYKIDTASPLNPEAAVLYEKDIQLFKSKVVDSVQVCTARLFDQPKIEDPYAISFSPWNPSVHDEAREKMLTQKKKPEEQHNKSVHVAGLSWVKPGSVQPFSKEEKTVAT
What is the function of this protein?
Component of the FTS/Hook/FHIP complex (FHF complex).  The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex).  Regulates apoptosis by enhancing phosphorylation and activation of AKT1.  Increases release of TNFSF6 via the AKT1/GSK3B/NFATC1 signaling cascade.  FHF complex promotes the distribution of AP-4 complex to the perinuclear area of the cell.
What are the official names of this protein?
AKT-interacting protein, Fused toes protein homolog.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family. FTS subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: CMOB_ALTMD
Sequence: MSKLEQTWFNECYTSLIDSPLAHWLQTLPALMDTWQRTAKHGEFDKWCRLLNKLPNTSPQQIDLSTSVTIGAKSDVDEYTQKQIEGLLRQFMPWRKGPFHVHGIHIDTEWRSDWKWDRVAPHISCLKGRNVLDVGCGSGYHMWRMLGEGANRVIGVDPTQLFFIQFHAIKQFIRNSYGPANNIHFLPMGIEDMQPLQAFDTVFSMGVLYHRKDPMAFLQQLKDQLRKGGELILETLVVDGDETTVLMAGERYAQMRNVWFLPSTDALTVWLSRLGFENIRVVDVNHTTLDEQRSTSWMDTQSLKDFLDPEDITRTIEGYPAPQRAVIVANKK
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: JZ21B_CHIGU
Sequence: MKTSVLLVILGIAAITVQCTASESVKQDSLRTFVDAVLGWNAEMASEARCGGWMAKCADSDDCCETFHCTRFNVCGK
What is the function of this protein?
Probable ion channel inhibitor.
What are the official names of this protein?
U14-theraphotoxin-Cg1a 2, U14-TRTX-Cg1a, Jingzhaotoxin-21.2, JZTX-21.2, Peptide F3-11.69.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 65 (Jztx-21) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: THIE_CLOB6
Sequence: MEINYELYLITDRRFLKGRQLKKVVEDAILGGVTIVQVREKDVSTKEFYNVAKEVKEVTDYYRVPIIINDRLDIAQAIDANGVHLGQKDMHLNIAREILGKDKIIGISVGNVKEALEAQNNGADYLGIGTIFPTGSKKDVDAIIGIDGLSKIKDSISIPSVAIGGINKTNFKDVLKTGIEGISVISAILDEDDIKLAANNLLINK
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: HSPG9_DICDI
Sequence: MATIFDILNTLNNNNFKNCKRQCPINKSNKTIIDIIPSMDVTMTNDKLIIETELAGISKDDIEIDIKDSILTIQGEKKKNLNKQQQQLVSEKSSTSPSTLDSKEDEPSIEEFEDDIKPKSATSTTTTTTKENKDDENKTKSSDKKFISERSFGNFKRYLDLTKVLYQLDLNSINTQFENGLLTITINKKLHYSNTIKININ
What are the official names of this protein?
Small heat shock protein hspG9.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
Protein: TRPC_HAEIN
Sequence: MMITQDFTKPIDSATVLQKIVLDKAQWVKAKEKEFPLSQFKQNIQNSDRSFYDALAKGTHQKPAYILECKKASPSKGLIRAEFNLEEIANVYKHYASAVSVLTDEKYFQGNFEFLPLVRDIVSQPVLCKDFMISEYQVYLARYYQVDAILLMLSVVNDETYRVLADLAHSLGMGVLTETSNEEEFERALALGAKIIGVNNRNLHDLTVDLNRVVELTKKYADCIPADVRIISESGIYNHKQIHQLQKVAHGFLIGSSLMGNQDLNNAVRSVIFGENKVCGLTRAQDVKIVYENGALYGGLIFAEHSKRSVSLRQAQELVTAAPLRFVGVFQNQEIDFIVKIASQLQLYAVQLHGAETEAFITALRQQLPKNTQIWKAISVNTEAQSAVDFTDDLNVDRYIFDSQTANQQGGTGKTFDWSLIPENLKHKIILAGGISPNNVEQAIAQGCLGLDLNSGVESSAGVKDQEKVRLVFNNIY
What is the function of this protein?
Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway.  The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain (By similarity).
What are the official names of this protein?
Tryptophan biosynthesis protein TrpCF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the TrpF family.
Protein: ORC1_KLULA
Sequence: MASTLAEFEVQWEIQKTDLKGNLIAETPRRRRRGDATEHEVINLVRYDGVRLYPGVTIVCKVEGADELSAYMIHEVRLNTSNYVELWCLNYLSWYEINAAERYKQLDGEFYETNKEKGDKFFEETFASQSIKNELYLTAELSEIYLRDLQFVANIKNEKEYLDSVNEGKMDSNMFLCRSACLPSGTNLADLDIHFFEEKIRSSNPKVSLEYLRDITLPKLPKPLNKSKVHAREKVVATKLQSDNTPSKKSFQQTVSKTNAEVQRIASTIVNEKEAISDNESDLSEYHESKEEFANASSSDSDEEFEDYQSAEELAIVEPAKKKVRSIKPDIPISPVKSQTPLQPSAVHSSPRKFFKNNIVRAKKAYTPFSKRYKNPKDIPDLNDIFQRHNNDLDIAALEERFRTVSAKGKMETIFSKVKKQLNSRNSKEEIVKAADFDNYLPARENEFASIYLSLYSAIEAGTSTSIYIAGTPGVGKTLTVREVVKDLMTSADQKELPRFQYIEINGLKIVKASDSYEVFWQKISGEKLTSGAAMESLEFYFNKVPATKKRPIVVLLDELDALVSKSQDVMYNFFNWATYSNAKLIVVAVANTLDLPERHLGNKISSRIGFTRIMFTGYTHEELRTIINLRLKYLNESSFYVDPETGSSYMISPDSSTIETDEEEKRKDFSNYKRLKLRINPDAIEIASRKIASVSGDVRRALKVVKRAVEYAENDYLKRLRYERLVNSKKDTSGNGTGNEELQSVEIKHITKALNESSTSPEQQFISGLSFSGKLFLYALINLIKKKQTDVQLGDIVEEMRLLIDVNGNNKYILELKRILFQNDSVDTKEQLRAVSWDYILLQLLDAGVVVRQYLKNERLSTIKLNISMEDAEQCLHEDEMLKTF
What is the function of this protein?
Component of the origin recognition complex (ORC) that binds origins of replication.  It has a role in both chromosomal replication and mating type transcriptional silencing.  Binds to the ARS consensus sequence (ACS) of origins of replication in an ATP-dependent manner (By similarity).
What are the official names of this protein?
Origin recognition complex subunit 1.
What is the protein family that this protein belongs to?
Belongs to the ORC1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SSUB2_RHILO
Sequence: MASHLGGLRDAPVVRVESLVRSFGPRTILDGLSLDIEKGEFVALLGRSGSGKSTLLRALADLDDKVSGSGRLETPDKKSVVFQDARLLPWKRVLENVVLGLDLPDAAERGRAALEEVGLNGRETAWPVELSGGEQQRVALARSLVRDPDLLLADEPFGALDALTRLRMHDLLRQLCARHQPAVLLVTHDVDEAVTLADRVLVLDKGAIAADIAIDIPKPRDHGHRRFGEIRSELLRHLGVETRPVLPV
What is the function of this protein?
Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Aliphatic sulfonates import ATP-binding protein SsuB 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3.A.1.17.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y274_BRUSI
Sequence: MTADVPNARLVDVELDESIGRSTPDVEHERAVAIFDLIEENSFHPVGDQKGGPYRLKLSLMESRLIFSITRENGDAVATHILSLTPLRRVVRDYFMIYESYYQAIRSATPSKIEAIDMGRRGLHNEGSQTLQARLKGKIEVDFDTARRLFTLVCVLHWRG
What are the official names of this protein?
UPF0262 protein BSUIS_A0274.
What is the protein family that this protein belongs to?
Belongs to the UPF0262 family.
Protein: ESXD_STAA3
Sequence: MTLSGKISVKAETIAHVVKELESISQKYDEIAQNFGKIAQLNYYSSEKAAHSMENGYSSAATVISGLKGPLSTLGGGVMNSAQKFFEADEHWGTEFAKLYYNIEG
What are the official names of this protein?
Type VII secretion system extracellular protein D, Ess extracellular protein D.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the ESAT-6 secretion system (Ess) / type VII secretion system (T7SS).
Protein: PSB1_PETHY
Sequence: MTKQQANWSPYDNNGGTCVAVAGADYCVIAADTRMSTGYNILTRDYSKIIKLADKCVMASSGFQADVRALQKVLASRHLIYQHQHNKQMSCPAMGQLLSNTLYYKRFFPYYSFNVLGGLDSEGKGCVFTYDAVGSYERVGYSSQGSGSTLIMPFLDNQLKSPSPLLLPAQDAVTPLSEAEAIDLVKTCFASATERDIYTGDRLEIVILNASGIRREEMELRKD
What is the function of this protein?
Non-catalytic component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.
What are the official names of this protein?
Proteasome subunit beta type-1, 20S proteasome alpha subunit F, 20S proteasome subunit beta-6.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PYRE_HALHL
Sequence: MYEYQEDFIRFALDRGVLRFGRFTLKSGRESPYFFNTGLFNSGTALSKLGRCYVESLVRAQIDFDLVFGPAYKGIPLATAVAMALAETRNRDVPYAFDRKEVKDHGEGGRLVGAPVEGRRAVIVDDVISSGISIREAAELITAEGGTVAAVAIALDRKERGRDEVSAVHEVEQTLGAPVVPIITLDHLETYLADHGGKGDTLDAIRQYRARYGAA
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: FSTL3_MOUSE
Sequence: MRSGALWPLLWGALVWTVGSVGAVMGSEDSVPGGVCWLQQGREATCSLVLKTRVSREECCASGNINTAWSNFTHPGNKISLLGFLGLVHCLPCKDSCDGVECGPGKACRMLGGRPHCECVPNCEGLPAGFQVCGSDGATYRDECELRTARCRGHPDLRVMYRGRCQKSCAQVVCPRPQSCLVDQTGSAHCVVCRAAPCPVPSNPGQELCGNNNVTYISSCHLRQATCFLGRSIGVRHPGICTGGPKVPAEEEENFV
What is the function of this protein?
The secreted form is a binding and antagonizing protein for members of the TGF-beta family, such us activin, BMP2 and MSTN.  Inhibits activin A-, activin B-, BMP2- and MSDT-induced cellular signaling; more effective on activin A than on activin B.  Involved in bone formation; inhibits osteoclast differentiation.  Involved in hematopoiesis; involved in differentiation of hemopoietic progenitor cells, increases hematopoietic cell adhesion to fibronectin and seems to contribute to the adhesion of hematopoietic precursor cells to the bone marrow stroma.  The nuclear form is probably involved in transcriptional regulation via interaction with MLLT10 (By similarity).
What are the official names of this protein?
Follistatin-related protein 3, Follistatin-like protein 3, Follistatin-related gene protein.
What are the subcellular locations of this protein?
Secreted. Nucleus.
Protein: LUXS_STRMU
Sequence: MTKEVTVESFELDHIAVKAPYVRLISEEFGPKGDLITNFDIRLVQPNEDSIPTAGLHTIEHLLAKLIRQRIDGMIDCSPFGCRTGFHLIMWGKHTTTQIATVIKASLEEIANTISWKDVPGTTIESCGNYKDHSLFSAKEWAKLILKQGISDDPFERHLV
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: MVP_ABMVW
Sequence: MDSQLVNPPNAFNYIESHRDEYQLSHDLTEIILQFPSTAAQLTARLSRSCMKIDHCVIEYRQQVPINATGSVIVEIHDKRMTDNESLQASWTFPIRCNIDLHYFSASFFSLKDPIPWKLYYKVCDTNVHQRTHFAKFKGKLKLSTAKHSVDIPFRAPTVRILSKQFSEKDVDFSHVDYGKWERKPIRCASMSRIGLRGPIEIRPGESWASRSTIGTAQPDTDSEMENELHPYRHLNRLGTSLLDPGESASIVGDQRAEPNITMSMGQLNELVRTAVQECVNSNCQASQAKSLK
What is the function of this protein?
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier.  Begomovirus genome is shuttled out of nucleus by Nuclear shuttle protein (NSP) and the movement protein transports the DNA-NSP complex to cell plasmodesmata and facilitates further movement across the cell wall.
What are the official names of this protein?
Movement protein BC1, Movement protein BL1.
What is the protein family that this protein belongs to?
Belongs to the begomovirus movement protein BC1 family.
What are the subcellular locations of this protein?
Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Host microsome membrane; Peripheral membrane protein; Cytoplasmic side. Host endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=Found on ER-derived vesicles.
Protein: APT_STRPZ
Sequence: MDLTNYIASIKDYPKAGITFRDISPLMADGKAYSYAIREIAQYACDKDIDMVVGPEARGFIIGCPVAVELGIGFAPVRKPGKLPRDVVSADYEKEYGLDTLTMHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGIVAGCAFLIELEGLNGRHAIRNYDYKVLMQFPG
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_VIBVY
Sequence: MATKRTFQPSVLKRKRTHGFRARMATKNGRKVINARRAKGRARLSK
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: RPK1_IPONI
Sequence: MKVAVNTFLLFLCSTSSIYAAFALNSDGAALLSLTRHWTSIPSDITQSWNASDSTPCSWLGVECDRRQFVDTLNLSSYGISGEFGPEISHLKHLKKVVLSGNGFFGSIPSQLGNCSLLEHIDLSSNSFTGNIPDTLGALQNLRNLSLFFNSLIGPFPESLLSIPHLETVYFTGNGLNGSIPSNIGNMSELTTLWLDDNQFSGPVPSSLGNITTLQELYLNDNNLVGTLPVTLNNLENLVYLDVRNNSLVGAIPLDFVSCKQIDTISLSNNQFTGGLPPGLGNCTSLREFGAFSCALSGPIPSCFGQLTKLDTLYLAGNHFSGRIPPELGKCKSMIDLQLQQNQLEGEIPGELGMLSQLQYLHLYTNNLSGEVPLSIWKIQSLQSLQLYQNNLSGELPVDMTELKQLVSLALYENHFTGVIPQDLGANSSLEVLDLTRNMFTGHIPPNLCSQKKLKRLLLGYNYLEGSVPSDLGGCSTLERLILEENNLRGGLPDFVEKQNLLFFDLSGNNFTGPIPPSLGNLKNVTAIYLSSNQLSGSIPPELGSLVKLEHLNLSHNILKGILPSELSNCHKLSELDASHNLLNGSIPSTLGSLTELTKLSLGENSFSGGIPTSLFQSNKLLNLQLGGNLLAGDIPPVGALQALRSLNLSSNKLNGQLPIDLGKLKMLEELDVSHNNLSGTLRVLSTIQSLTFINISHNLFSGPVPPSLTKFLNSSPTSFSGNSDLCINCPADGLACPESSILRPCNMQSNTGKGGLSTLGIAMIVLGALLFIICLFLFSAFLFLHCKKSVQEIAISAQEGDGSLLNKVLEATENLNDKYVIGKGAHGTIYKATLSPDKVYAVKKLVFTGIKNGSVSMVREIETIGKVRHRNLIKLEEFWLRKEYGLILYTYMENGSLHDILHETNPPKPLDWSTRHNIAVGTAHGLAYLHFDCDPAIVHRDIKPMNILLDSDLEPHISDFGIAKLLDQSATSIPSNTVQGTIGYMAPENAFTTVKSRESDVYSYGVVLLELITRKKALDPSFNGETDIVGWVRSVWTQTGEIQKIVDPSLLDELIDSSVMEQVTEALSLALRCAEKEVDKRPTMRDVVKQLTRWSIRSYSSSVRNKSK
What is the function of this protein?
Possible role in short-day photoperiod floral induction.
What are the official names of this protein?
Receptor-like protein kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
[Isoform INRPK1]: Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform INRPK1b]: Secreted. SUBCELLULAR LOCATION: [Isoform INRPK1c]: Cell membrane; Single-pass type II membrane protein.
Protein: PRR3_RAT
Sequence: MPKRKKQNQPQPPQHLALSERDEPGDEEDERPMGPPSLLGPPPMANGKPGDPKSVFHRGPPGSRGPMIPPLLSLPPPPRGRGHIRGGLGPRSSPYGRGWWGVNTEPPFPGPGHGGPSREIFYQEPRNPRRLKSWSLVKNTYPPKDSPPMMEDKSDRPVCRHFSKKGHCRYEDHCAFYHPGVNGPPL
What are the official names of this protein?
Proline-rich protein 3, MHC class I region proline-rich protein CAT56.
Protein: Y950_SYNJA
Sequence: MKVAYFDCAAGIAGDMCLGALLDCGLPLEYLNQQLQALGLEGEYSLQVCRVQRCGQPALQAVVEVLDESPPARPWREIQALIAGSRLAPAVKARSLKVFEKLAQAEAKVHQVPLETVHFHEVGAVDALVDIVGTCVGLDWLQVERVISSPHPIGGGWVDTEHGKLAVPVPAVIELWEMGRVPVFSNGVEAELVTPTGAALAVALAEAFGPCPPLRLEKVGRGAGSRELPIPNIFRLWIGQSQGEEPTEIVSVLQTQIDDLNPQVIAYTCEQLLALGAWDVFTQPITMKQGRPGVLLTVICPPERVPECQDFIFRETTTLGIRHSQQQRTVLERRIERVETPYGLVDIKVACRHGHIVNAQPEFRDCVARAQEFRVPVQTVWLAAQAAWQKRLQGDPA
What are the official names of this protein?
Putative nickel insertion protein.
What is the protein family that this protein belongs to?
Belongs to the LarC family.
Protein: KITH_CHLAA
Sequence: MTRPSDGGRIEVICGCMYSGKTEELIRRMRQVRIARQSYRIFTPRMDTRYAEGQVASHSGSRLEAITVATMKDILAHAEDAQVVAIDELHLFDDDPAEMVRGCQWLANRGVRVIVAGLDLNYRAEPFPAMMHLLALAEQVDKLYAICVKCGAYATRSQRLIDGKPAPADAPTIVVGGLDMYEARCRTCYEPAV
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.