PharMolix/UniProtQA huggingface dataset:
Protein: PHS_PSYA2
Sequence: MSSLSNQQVDLQLEELPGWQRDGNAIVKTYHFSDFVEAMSFMNQAAFHAEALEHHPEWSNAYNVVEVRLTTGDTGGITSHDVRLAKRMEHIVQPKCL
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: RLMN_CLOAB
Sequence: MENILDYNEAELKQWMDKNGEKTFRAKQFFDWIYNGTFDFKDMKNLPQSTRERLEKNFYIGMPSVVKRLNSKKGDTVKFLFRYNDGNIIECVVMKYDYGNSICISTQVGCRMGCSFCASTIGGRVRDLTSGEILAQILKAQKEIGERISNIVLMGSGEPLDNYDNVIKFIRIVNSEKGLNIGQRHITLSTCGIVPRIYDLMKENLQITLAISLHASDDETRKKIMPIANRYSISEIIDCCKKYSDFTGRRITFEYSLVKDVNDDKESAKKLGELLSGMLCHVNLIPVNTVNETSYEKPESSKIKKFCDTLLKYKIESTIRKEMGADINAACGQLRRNYIEESEGK
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAA22_MYCTU
Sequence: MRNGNLAGLLAEQASEAGWYDRPAFYAADVVTHGQIHDGAARLGEVLRNRGLSSGDRVLLCLPDSPDLVQLLLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSRVAEAAELMSEAARVAPGGYEPMGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRKALRLTPEDTGLCSARMYFAYGLGNSVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVLYGVPNFFARVIDSCSPDSFRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQTFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAKGYWNRPDSPVANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVAVRESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGKLVRGALRKQSPTKPIWELSLTEPGSGVRAQRDDLSASNMTIAGGNDGGATLRERLVALRQERQRLVVDAVCAEAAKMLGEPDPWSVDQDLAFSELGFDSQMTVTLCKRLAAVTGLRLPETVGWDYGSISGLAQYLEAELAGGHGRLKSAGPVNSGATGLWAIEEQLNKVEELVAVIADGEKQRVADRLRALLGTIAGSEAGLGKLIQAASTPDEIFQLIDSELGK
What is the function of this protein?
Catalyzes the adenylation of p-hydroxybenzoic acid (pHBA) to form p-hydroxybenzoic acid-AMP (pHBA-AMP), which is converted directly to p-hydroxybenzoyl-S-FadD22 (pHBA-S-FAdD22) thioester intermediate in a CoA-independent manner by attack of the phosphopantetheine thiol of FadD22.  Usually, this intermediate primes the biosynthesis of the phenolphthiocerol (PPOL) by presenting the pHBA starter unit for elongation by Pks15/1, but M. tuberculosis lacks Pks15/1 due to a natural frameshift and thus is unable to produce PPOL.
What are the official names of this protein?
p-hydroxybenzoic acid--AMP ligase FadD22, p-HB--AMP ligase FadD22, p-hydroxybenzoic acid-AMP synthetase, p-HB-AMP synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: G6PI_PECAS
Sequence: MKNINPSQTAAWQALQTHFDAMKDVKISELFAQDSDRFAHFSATFDDQMLVDYSKNRITAETMGKLHALARETDLPAAIHAMFAGEKINRTEDRAVLHVALRNRSNTPILVDGKDVMPEVNAVLAKMKDFSERVIGGEWKGYTGKTITDVVNIGIGGSDLGPFMVTEALKPYKNHLNMHFVSNVDGTHIAETLKPLNPETTLFLVASKTFTTQETMTNAHSARDWFLKTAQDEKHVAKHFAALSTNAKAVGEFGIDTNNMFEFWDWVGGRYSLWSAIGLSIILSLGFDNFEKLLSGAHAMDKHFASTPAEKNLPVLLALIGIWYNNFFGAETEAILPYDQYMHRFAAYFQQGNMESNGKSTDRNGNPVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKLVPCDFIAPATSHNPLSDHHSKLLSNFFAQTEALAFGKSREVVEAEFTAAGKSAKEVEHVAPFKVFEGNRPTNSILLRDITPYSLGALIALYEHKIFTQGAILNIFTFDQWGVELGKQLANRILPELESDSTIDSHDSSTNGLINRFKAWRN
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUB_LATSS
Sequence: MDGIIPLYKERGMTSNDCVFKVRRILHMKKVGHSGTLDPNVDGVLPICIGQATKVVDQLVHSGKVYTGEITLGLSTTTEDLDGEVVEEQQLTEPISTEKIKETLASFLGESIQIPPMFSAVKVNGRRLYDYARAGDPVERPQRKITITQFDLQGEPEFDAKTGRQTFRFIAGCSKGTYIRTLAVDFGRKLGLPAVMSDLTRLKSGGIQIGSCVTLAQLAEAADNGQLADILIPLDHVFEENVKIALDDDQWAKILNGVFLTFPEQTEEILALTYEGHIKALYQVANAKQHLYRPYKMYLQNQGTH
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: CRBA4_MOUSE
Sequence: MTLQCTKSAGHWRMVVWDEEGFQGRRHEFTAECPSVLELGFETVRSLKVLSGAWVGFEHAGFQGQQYVLERGDYPGWDAWGGNTAYPAERLTSFRPVACANHRDSRLTIFEQENFLGRKGELNDDYPSLQAMGWDGTEVGSFHVQSGAWVCSQFPGYRGFQYILESDHHSGDYKHFREWGSHAHTFQVQSVRRIQQ
What is the function of this protein?
Crystallins are the dominant structural components of the vertebrate eye lens.
What are the official names of this protein?
Beta-crystallin A4, Beta-A4 crystallin.
What is the protein family that this protein belongs to?
Belongs to the beta/gamma-crystallin family.
Protein: KUP_LEVBA
Sequence: MRKERLEKGSWLGMLITLGVVYGDIGTSPLYVMNALINDAGPLKNATPDYVIGSVSLIFWTLMLITTVKYVLVALRADNHHEGGIFALYALVRHRAKWLIFVALIGGAALLADGTLTPAVTVTSAVEGLKGLPDLRAFSQYSWLVPLSVTLILVSLFTIQVLGTAVVGRSFGPMMLLWFIVIGGIGLLNISQAPAILRAFSPVYAIQVLFSPTNKMGIFILGSVFLATTGAEALYSDMGHVGKANIDATWPFVYAMLILNYLGQGAWMLTHSQGPAWRNVTNINPFYEMIPSGGRIAMIVLATVAAIIASQALITGSYTLVDEAVGLKFLPRMIIKHPSNVRSQIYIGAINWLLCLVTLSIVWLFQTSAHMEAAYGLAITLTMLMTTILLSQWVQMKGHRFWSLALLAGFGLLETLFLVASLTKFIHGGYLTLGLTLMIFLIMVVWFFGNRRRLRYNQADEQISLLNYRSQLIQLSQDDNQPLFATNLVYLAKVDQLHRVKRSILYSILDKRPKRAKVYWFITINETNRPYDCSYSVDMLGTRNVVEVRLNLGFRKSQHINRYLRAIVTSLIADHSIDPQYSNYGITQPRQVGDFKFVVQNQQIMDLAGNPTMHQFDRFLIGGRIFLQNITPSPAIWYGLEFSDVLEETIPLFTKPMTDPALVHLAKRQTTRHQV
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MSHC_TSUPD
Sequence: MRSWPSPAVPTLSGPSVPLRLYDTSDQAVRSVNPGAVSGMYVCGITPYDATHLGHAATYLTFDLINRVLRANGHEVHYVQNVTDVDDPLFERAARDGIDWRDLGARETDLFCEDMQALRVLAPQDYIGAVESIDEVIALVGRLLENGAAYIVDDPEFPDVYYRTDATEQFGYESGYDRATMERFFAERGGDPDRPGKRDPLDALLWRAARPGEPSWPSPQGPGRPGWHIECAAIAQNRLGVGFDIQGGGSDLIFPHHEFSAAHVEADTGERRFARHYVHAAMIGLDGEKMSKSRGNLVFVSTLRRAGVDPAAIRLGLFEGHYRTDRAWSDEVLARAQARLDLWRNAFAAASSPDGAELVGRLRRYLADDLDTPKALSALDAWAHRAVTSGGPDPDGPSTVATAVDALLGVAVSA
What is the function of this protein?
Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
What are the official names of this protein?
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase, L-Cys:GlcN-Ins ligase, Mycothiol ligase, MSH ligase.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
Protein: RPIA_PHOPR
Sequence: MTQDEMKKAAGWAALEYVTKGSIVGVGTGSTVNHFIDALETRKEEIKGAVSSSVASTERLEKLGIPVFEANEVAGLDIYVDGADEINAEYDMIKGGGAALTREKIVAAISDKFICIVDDTKQVDVLGQFPLPVEVIPMARSFIGRELVKLGGDPEYREGVVTDNGNIIIDVHNMAITDAKDMEKKINALPGVVTVGLFAARGADVLLVGAPEGVRKFEK
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: CATA_STAA3
Sequence: MSQQDKKLTGVFGHPVSDRENSMTAGPRGPLLMQDIYFLEQMSQFDREVIPERRMHAKGSGAFGTFTVTKDITKYTNAKIFSEIGKQTEMFARFSTVAGERGAADAERDIRGFALKFYTEEGNWDLVGNNTPVFFFRDPKLFVSLNRAVKRDPRTNMRDAQNNWDFWTGLPEALHQVTILMSDRGIPKDLRHMHGFGSHTYSMYNDSGERVWVKFHFRTQQGIENLTDEEAAEIIATDRDSSQRDLFEAIEKGDYPKWTMYIQVMTEEQAKNHKDNPFDLTKVWYHDEYPLIEVGEFELNRNPDNYFMDVEQAAFAPTNIIPGLDFSPDKMLQGRLFSYGDAQRYRLGVNHWQIPVNQPKGVGIENICPFSRDGQMRVVDNNQGGGTHYYPNNHGKFDSQPEYKKPPFPTDGYGYEYNQRQDDDNYFEQPGKLFRLQSEDAKERIFTNTANAMEGVTDDVKRRHIRHCYKADPEYGKGVAKALGIDINSIDLETENDETYENFEK
What is the function of this protein?
Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
Protein: HISX_CALS4
Sequence: MIEMFDFTKEVDIGIFNKIQNRSKLENKEIAKRVEDIIENVRERKDKALFEYTYMYDGINLNSETVKVKEEEIKRAYEEVKEDFLKALDKAIKNITEFHEKQKEKTWMDFKEGIVYGQVLRPLSSVGIYVPGGTASYPSSVLMNGIPAKVAGVERIVMVSPAGKKGISPYVLVAADKIGIKEIYKIGGAQAVAALAFGTESIPKVDKIVGPGNIYVAMAKRALYGYVDIDMVAGPSEILVIADESASPKYVAADLLSQAEHDVMASSILVTTSKELAEKVKKEIERQMEYLERKEIIAESLKNFGAIIVIDNLKEAIGIANEIAPEHLELVIENPFEILGEIKNAGAVFLGEFSPEPLGDYLAGPNHVLPTSGTARFFSPLSVRDFVKKMNVLYYSKEALSSVKDDVITLAEAEELTAHANSVKVRFYND
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: LEU3_PHACH
Sequence: MSKRTFKIVILPGDGIGPEVVAEATRVLEVVSASSSDVEIKLETHDFGGCSIDKHGEPLTAATLEACKLADAILLGAIGGPKWGVNSKVRPEQALLALRKALGLYANIRPANFASDSLLAYSPLKPSVARGVDIIVIRELIGGAYFGERKELGARAQEDAAWDTMIYSVPEVQRITRSRRQVASPDPPLPVHSIDKANVLASSRLWRKVATETIQNEFPQLKLDHHLVDSASMLIVANPKKLNGVILTENLFGDILSDESSVIPGSLGLLPSASLAARPLWPNTAHRRSSPRRVYEPIHGSAPDIAGQGIANPIGTILSAAMLCGTRSVWRSPAKAIEAAVEGARRQGDRREGLRTADLGGSSKTKDIGHKVVEILKATL
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, IMDH, Beta-IPM dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPC10_DROME
Sequence: MQIKPIITYSGSCPLFRSLESQILNAIPLDTCEWRRTFQRPTKHVRLEAQAQQFNVAALEKYKQGDWSILEHPILHIFVTECNDVDTYKATIREAIDIWLKTLTSYGVSDWMILLVETLDMRKTKNFMPRTTVLDKIRLDFGTKNDDRCISVLNPAKFEQKSTESFRCLVQRIRFLMLTSYNRNIVKYEELIRSKREKRNIEGWDFRQYFFMQEDLALIFEKLELPTEALIQYDELDAMFSQFITHTGLNEKQQWLNHFRKPLDAFHGICLTRADKFEMRNKIRDEGVSLLEFRNYLFERQAYLLLTCNDIPEIAKRLLNFLFSTLREVELIKLECQEGALCCWEFVCALEVLQLCEQAMEPNELTCFQHCAPIWNLAKDKLYELGKLCGLLPGCTPTSEQLHIVVQLSSGIGDAPSEQHQFLQATPQLRDRSPNRKPKKSGAEQLKEALGSNQAFQKLYLELAELAISTYKHVTRLRSARLVGLDLGNFYCALNEPHKAVGFFTDLLRELKAENWHMLSSQTLLELANCYRKMGDSLAYTKTCSSISCCAELETLVRTFYFDEFLKSLKTLKTTLSAQPSIENANYCVLEDHFRILDIEVVNQKPIIQDDYILVQLKVESLYPRGVVAENVKLCYELEASSLELAMENVSLTASPSTVKAKDTSSRLKVSLQLVYKQDNRLHSAAVACDLPKSKQPVRRTSSTKRKLSPSVQADFTNFVQAENIALQPGVNLIEMKAKATRVGCWQFKQLCISMSSLEFLSEQLPFMPATFEISTKPASATLEFKTLIAGIVQPISLNVSGGSFIFPPDAKITLRCSKNLRIRQARNTDDEAAYNDDQSFESTLQVPLVQFKSFEERRIPLEVLTDMPGRKVSKHHEHHIALNCPWSRTELPIAVDFQPAMEATCRLHTCGTQKFLQVIMKGMEAHLLLQHAQVKCDVPGVQLLDLNPESQQPIEIYKSLTVTYLYEIQVEPLKTEHELPVVKVHFVIKYASLSQPDVWRTYGCAFDLVDYTTLFKLQAQLEPNELCRLRTVCNMNLKITKVHENPYTDLMYEVLNDQNLWAVCGRSAGVVSMKDVDSHSISLDVMPLSTGFLPMPSIRLSKYTAGGKSKTDGHSKVHPFPPGQVYNSTKSMQIHVIASVAGDQ
What is the function of this protein?
May play a role in vesicular transport from endoplasmic reticulum to Golgi (By similarity).  Has a role in one of the several mechanisms underlying dendritic localization of Shal channels.
What are the official names of this protein?
Trafficking protein particle complex subunit 10, Shal Interactor of Di-Leucine Motif, Trafficking protein particle complex subunit TMEM1, Transport protein particle subunit TMEM1, TRAPP subunit TMEM1.
What is the protein family that this protein belongs to?
Belongs to the TMEM1 family.
What are the subcellular locations of this protein?
Golgi apparatus, cis-Golgi network. Cell projection, dendrite. Perikaryon.
Protein: ORR8_ORYSI
Sequence: MSSPHVLVVDDTHVDRHVVSMALMRHNVRVTAVESVMQALMFLDSEHDVDMIVSDYCMPDMTGYNLLMEVKKSPKLAHLPVVIASSDNIPERIRKCLDGGAKDYILKPVKIVDVPRIMKYI
What is the function of this protein?
Functions as response regulator involved in His-to-Asp phosphorelay signal transduction system.  Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes.  Type-A response regulators seem to act as negative regulators of the cytokinin signaling.
What are the official names of this protein?
Two-component response regulator ORR8, Type A response regulator 8, OsRR8.
What is the protein family that this protein belongs to?
Belongs to the ARR family. Type-A subfamily.
Protein: DNAK_MANSM
Sequence: MGKIIGIDLGTTNSCVAVMDGDKPRVIENAEGERTTPSIIAYTQDNEVLVGQPAKRQAVTNPKNTLFAIKRLIGRRFEDQEVQRDVNIMPFQIIKADNGDAWVDVKGDKLAPPQISAEVLKKMKKTAEDFLGETVTEAVITVPAYFNDAQRQATKDAGRIAGLEVKRIINEPTAAALAYGLDKGKGNQTIAVYDLGGGTFDLSIIEIDEVGGEKTFEVLATNGDTHLGGEDFDNRVINYLVDEFKKEQGVDLRNDPLAMQRLKEAGEKAKIELSSAQQTDVNLPYITADATGPKHLNIKLTRAKLEALVEDLVARSMEPVKVALSDAGLSVSQIDDVILVGGQTRMPLVQQKVAEFFGKEPRKDVNPDEAVAVGAAVQGGVLAGNVTDVLLLDVTPLSLGIETMGGVMTTLIEKNTTIPTKKSQVFSTAEDNQSAVTIHVLQGERKQASANKSLGQFNLEGINPAPRGMPQIEVTFDIDADGIIHVSAKDKGTGKEQQITIKASSGLSDEEIQQMVRDAEANAEADRKFEELVQARNQADALVHSTRKQLTEAGDKLSADDKAPIEKAVNELEAAAKGEDKAEIEAKIQALIQVSEKLMQAAQQQAQADAGAQQAQGNNGGDDVVDAEFEEVKDNK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: DIUH_ACHDO
Sequence: TGAQSLSIVAPLDVLRQRLMNELNRRRMRELQGSRIQQNRQLLTSI
What is the function of this protein?
Regulation of fluid secretion.  Stimulates primary urine secretion by Malpighian tubules and causes a dose-dependent stimulation of cAMP levels in the tubules.
What are the official names of this protein?
Diuretic hormone, DH, Diuretic peptide, DP.
What is the protein family that this protein belongs to?
Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
What are the subcellular locations of this protein?
Secreted.
Protein: CHI1_CASSA
Sequence: ACGGGGGDVGSLISASLFDQMLKYRNDPRCCXXGF
What is the function of this protein?
Defense against chitin-containing fungal pathogens.
What are the official names of this protein?
Basic endochitinase CH1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 19 family. Chitinase class I subfamily.
Protein: GLO2_SYNP6
Sequence: MRIDCLPALQDNYIFLLVDVEQRQAAVVDPAEAEPVLAALQAEGLTLTAILNTHHHGDHVGGNRRLLRQFPEAAVSASAVDRDRIPGQTVLLEAGDRLQICGQTAEVLFVPGHTRGHIAYYFPEVAEGNPRGALFCGDTLFAGGCGRLFEGTPAQMLDSLQQLRSLPDDTAIYCAHEYTLNNLRFALTVEPDNFDLQQRYQAVAIARQQGQATIPSRLDIEKATNPFLRWDQAALQAAVSSQDPVQTLARLRSRKDQF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: SYI_ZYMMO
Sequence: MSDQKSADATQARDWRPTVFLPKTSFPMKAGLAKKEPEILARWQKEDLYQQLREQRKGAERFILHDGPPYANGDIHIGHALNKILKDIIMRSQTLLGKDVPYIPGWDCHGLPIEWKVEEQFRKKKLNVDKDVNAVEFRQECRKYAVHWVDTQRQEFKRLGVLGEWDNPYLTMNFEAEAIIAGELMRFSETGQIYRGAKPVLWSVVEKTALAEAEVDYADVDSTTIDLAFKITDSKIPELVGGYAVIWTTTPWTIPANRALAYGPDIDYVLVDLNGKHYLFAEALLEDSLKRIGHEGDAPVLWRGKGAELDGSIAQHPMFEKGGFFAEPRPFLGGSHVTTEAGTGIVHMAPDYGEDDFLLCKAHNIDPVFAVEDDGRYRKDWLWMGGEGLVISPKINAADGPICSDLREVGALLATSVLHHSYPHSWRSKAKLIYRCTPQWFIALDRPVEKGAIAGKTLRETALKAIDEVSWFPAKGKNRIQTMVEGRPDWVISRQRAWGVPITLYVNRESGDYLRDPEVNARILAAFRKEGADAWFKANHQLFLGDKYRLEDYEPVNDILDVWFDSGSTHAFVVEARYGEGTRAQLYLEGSDQHRGWFQSSLLESCGSRGHAPYEAVLTHGFTLDGTGRKMSKSVGNVIDPLKVINESGADILRMWVASTDYNEDVRISKEVLSGTSDGYRKLRNSFRYLLGALEGFSEEEKVDLADLPELEKYILHLLAELDQALHESVNGFAFNRYLRLLSDFVNNDLSAFFFDIRKDRLYCDVGEAAPQGTEERRAYRTVLDILFHALVRYAAPILCFTAEEVWLHRFPDAGSVHLSVWPEVDGQWKNAVLGEKWAVIREQRQIVTEKIEPLRREKIVGSSLEAEVTLPVDAATAKILSSVDFSEICITAKINLVDASDAAITVDRTQNHKCGRCWQHLPEVEEDGALCDRCKSVVGE
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LON_METSB
Sequence: MESFAPTRKGRAVFSADAAATAAPGSAGAGETLDPAKDALIIVPVRGFVLFPGIVMPVVLNGPAAIAAAQEAVRQQRSVGILMQRESGAEEASPLNMHRFGVVANILRYITAQDGGHHLICQGEQRFHVEEFLRERPYLAARVKRIEEPDERSPDIEARFVHLQGQASEALQLLPQTPPELIAAVNSAPSPGALTDLVAAYMDASPAQKQDILETIDLRARMDMVAKLLAQRIEVLRLSQEIGRQTKASLDERQREMLLREQMASIQRQLGEGDGKAQEIAELTEAIAKAKMPAEVEEAARKELRRLERMPDASAEYGMIRTYIDWLIELPWSLPEEAPIDIAEARRILDADHFGLDKIKQRIVEYLAVRKLAPQGKAPILCFVGPPGVGKTSLGQSIARAMGRKFVRVSLGGVHDEAEIRGHRRTYVGALPGNIIQAIRKAGARNCVMMLDEIDKMGASAHGDPGSAMLEVLDPEQNSTFRDNYLAVPFDLSRVVFIATANMLDTVPGPLRDRMEIIALTGYTDREKLEIARRYLVRRQLEANGLKPDQVEIDDDALIEIIRGYTREAGVRNLEREIGRVLRHVAVRIADGSASHVHVSRAELTELLGQQRFEDEVAMRLSVPGVATGLAWTPVGGDILFIEATRAPGHGKLTLTGQLGEVMRESVQAALSLIKSRAAELGVDPESFDKTDIHVHVPAGATPKDGPSAGVAMFIALVSILTGRLVRNDTAMTGEISLRGLVLPVGGIKEKVVAAARAGLTRVLLPARNRRDYDEIPQDTREKLEFVWLEKVDDAMAAAFEGMAATPAPN
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner.
What are the official names of this protein?
Lon protease, ATP-dependent protease La.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHEW_KLEAK
Sequence: MAGLATVSKLAGETVGQEFLIFTLGNEEYGIDILKVQEIRGYDQVTRIANTPDFIKGVTNLRGVIVPIIDLRVKFAQQGVSYDENTVVIVLNFGQRVVGIVVDGVSDVLSLTAEQIRPAPEFAVTLATEYLTGLGALGERMLILVDIEKLLSSEEMALVDNVAKSH
What is the function of this protein?
Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors.
What are the official names of this protein?
Chemotaxis protein CheW.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_ECO24
Sequence: MIEFVYPHTQLVAGVDEVGRGPLVGAVVTAAVILDPARPIAGLNDSKKLSEKRRLALYEEIKEKALSWSLGRAEPHEIDELNILHATMLAMQRAVAGLHIAPEYVLIDGNRCPKLPMPAMAVVKGDSRVPEISAASILAKVTRDAEMAALDIVFPQYGFAQHKGYPTAFHLEKLAEHGATEHHRRSFGPVKRALGLAS
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_PSYCK
Sequence: MDLKTVTGAAVELSDTAFGREFNEALVHQVVTAYLAGARQGTRAQKTRAEVSGGGIKPWRQKGTGRARAGSIRSPIWRGGGRAFAAKPQDWSQKVNRKMYRGAMQCILAELIRQERLILVEEISVSGPKTKELIAKLGELNASRALIVTKEVDENLYLAARNIPHVNVLDTSEVDPVSLIAFDKVIMTVEAAKQFEEALA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: SYC_ACIBS
Sequence: MQPFVLYNSEQRKKVEFVPRKEGHIDMYVCGMTVYDYCHIGHARVMVAFDYIIRFLRSQGWKVRYIRNITDIDDKIIKRANENGETIQQLTMRFIDAMNEDAANLGCLAPDEAPKATEYIDQMQNMIGNLVNKGAAYPASNGDVYFEVTKFEKYGRLSGRKLDDMQAGASERVDVEVEKKHPFDFVLWKHAKENEPSWASPWGNGRPGWHIECSAMSTCCLGNHFDIHGGGSDLMFPHHENEIAQSEASTGEQYVNYWIHVGFINVDGEKMSKSLGNFFTIRDVMEKFHPEVIRYFIVSSHYRSPVNFSDVALKEAKTSLTRFYHSFKAYQQVYGQTTTETLDQSFVERFNNAMCDDFNTAEAMAVLFELNKELNRAVKEEQADQATVLYSTLRHLTNILGLVQHNVDDFLKSDIGQEALALSDAEIEDFIQQRVDAKKAKDFAKADSIRQSLLEQGVVLEDTRQGTVWRRAD
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRD_SACD2
Sequence: MYSFIRNCLFKLDAEVSHELSLDWLGAFERLHMLKPFALKVTPSPINVMGIDFPNRVGLAAGLDKNGDFVNALGQLGFGFVEIGTITPLAQSGNPKPRLFRLPEHQAIINRMGFNNKGVDHLVAQVQKRRYPGVLGINIGKNKITPEENALDDYVKCMDKVYAHADYITVNISSPNTPGLRNLQFGETLANLIAGIKQAQDRLAQTHDKYVPVAVKIAPDMTAEEIHSVADTLVNGNIDGVIATNTTISREAVQGHINADEAGGLSGLPVRDKSTEVIATLSAHLQGAMPIIGVGGIVEGADAQAKIAAGASLVQIYSGFIYKGPKLIAEAADAIASAG
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CHS3_RUTGR
Sequence: MAAVTVEEIRKAQRADGPATVLAIGTATPANYVTQADYPDYYFRITKSEHMTDLKEKFKRMCDKSMIRKRYMHLTEEILKENPNMCAYMAPSLDARQDIVVVEVPKLGKEAAAKAIKEWGQPKSKITHLIFCTTSGVDMPGCDYQLTKLLGLRPSVKRFMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPVDTHLDSLVGQALFGDGAAAVIVGADPDESIERPLYQLVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLKEAFGPIGISDWNSIFWIAHPGGPAILDQVEEKLELKEEKLRATRHVLSEYGNMSSACVLFILDEMRKKCAEEGMATTGEGLEWGVLFGFGPGLTVETVVLRSVPIKA
What is the function of this protein?
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
What are the official names of this protein?
Chalcone synthase 3, Naringenin-chalcone synthase 3.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: CLPP_PINST
Sequence: APTEADATWVDLYNRVMIHQPASSYYAAEMHNEAKTDNPEEVLDLDRDVFMSAAYGIVDTVWYVQAELVNGRGGAVVAGL
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins (By similarity).
What are the official names of this protein?
Putative ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp, PS7/PS12.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CINA_BACHK
Sequence: MNAEIIAVGTELLLGQIANTNAQFLSEKLASIGINVYYHTVVGDNNKRLQQAIEVAEERADMLIFTGGLGPTKDDLTKETIASSLAEELVYDEKALASISDYFKRTGREFTENNKKQALVLDGATVFANDHGMAPGMGLNKNGKVYILLPGPPKEMKPMYVSYVEPFLRNFTTGENIYSRVLRFFGIGESQLEVKVQDLIDGQTNPTIAPLANDGEVTLRLTAKHQNVDEAEKLIQHVEDLILERVGEFFYGYDQEFLHDKAIELLKKKGLTLACAESLTGGLFGNQVTESAGVSSVFKGGVICYHNDVKQHVLHVPEEVLFTDGAVSKECARYLAENVKELLEADIGISFTGVAGPDASEHKEPGTVFVGLAIKDEPTVVFPLNLSGSRQQIRERSAKYGFYHLYKKLEEI
What are the official names of this protein?
Putative competence-damage inducible protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.