PharMolix/UniProtQA huggingface dataset:
Protein: GWL_DANRE
Sequence: MEARGLACESSNSAVKAPSIEDFVLVKPISRGAFGKVYLARKKCNSKLYAIKVVKKAEMVDKNMTEQMRAERDALALSKSPFIVHLFYSLQTATKVYLVMEYLIGGDVKSLLHIYGYFDEDMSLKYISEVALALDYLHRHSIIHRDLKPDNMLISNEGHIKLTDFGLSKVKLDRELNLMDILTTPSLVKPTKDYFRTPGQVLSLISSLGLNTPVIEGKRHSSTVLGSPMSCGKVKQRNRSLGSPLMKRRAEYMNSPVCTSRALASNSVFSPVLLARSLTPRLLKSGKRLDTMSVGSTHSCMLPSTTDSENCVSPMWEDEQNLHDVENIPQLNGREVDNRKSRNVPLTPVEKRKTLPARAQDHRPVFTPLNNQVTNSRNIKPDLSAKRLQFGATDNSATPLEKTVPHQSVGNGLIKPEPLKELKSSVKRAFEEVEKSPEQAEILFKKNDAAYERSFQIPEKTSRAHTGLTGIFSIVGLDDVKSAPKCQQFNERTGPKQSSPIAVAKNLFCELEDQGEEGGKAEPNSSSSTSPGDERNIRRSLSLESDVSAHEMSLVANTPQKLSDAKQEVLSSSFEELDENEISAVTPMARPTVATPKHSSAKQRRGECERSLLDHPHGLSDSMIKSPGFLKPKNVVAFRSYCSSINRSCTSHLSLASFDAMEMSASASFHNAVTPVQKKRPSLSNSLYQTPQQMVVSHTPYRTPKSVRRGPERVEGAPILGTPDYLAPELLLGKPHDFMVDWWALGVCLFEFLTGVPPFNDETPQLVFQNILNRDIPWPDGEEELTLNSRNAIEILLTMDTLKRAGLKELKDHPFFDGVDWENLHHQTMPFIPQPDNETDTSYFEARNTAQHLTVSGFSL
What is the function of this protein?
Serine/threonine kinase that plays a key role in M phase by acting as a regulator of mitosis entry and maintenance.  Acts by promoting the inactivation of protein phosphatase 2A (PP2A) during M phase: does not directly inhibit PP2A but acts by mediating phosphorylation and subsequent activation of arpp19 and ensa at 'Ser-62' and 'Ser-74', respectively.  ARPP19 and ENSA are phosphatase inhibitors that specifically inhibit the ppp2r2d (PR55-delta) subunit of PP2A.  Inactivation of PP2A during M phase is essential to keep cyclin-B1-CDK1 activity high.  Following DNA damage, it is also involved in checkpoint recovery by being inhibited (By similarity).  May be involved in megakaryocyte differentiation (PubMed:19460416).
What are the official names of this protein?
Serine/threonine-protein kinase greatwall, GW, GWL, Microtubule-associated serine/threonine-protein kinase-like, MAST-L.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Cleavage furrow. Note=During interphase is mainly nuclear, upon nuclear envelope breakdown localizes at the cytoplasm and during mitosis at the centrosomes (By similarity). Upon mitotic exit moves to the cleavage furrow.
Protein: MURI_TRIEI
Sequence: MTTETRQKRIGIFDSGIGGLTVLRELYRQLPKESILYFADTARLPYGTRTTEEILQFVDEIITWLVKSGVKMVLMACNTSSALALEKVKSKFDVPILGLIVPGANTAVKQGKRIGVIATPATAASNAYRYAILEANASVQVWQVGCPYFVPLIEQNQLHDPYTYQIAEEYLMPLIQQQIDTLVYGCTHYPYLEPILRSLLPKSVIFVDPAVSLVKVVARELKIMNLENDKTPKPTKFVVSSSPQKFADLSLQLLGYKPDVQVISLPAMLK
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: CCMN_SYNE7
Sequence: MHLPPLEPPISDRYFASGEVTIAADVVIAPGVLLIAEADSRIEIASGVCIGLGSVIHARGGAIIIQAGALLAAGVLIVGQSIVGRQACLGASTTLVNTSIEAGGVTAPGSLLSAETPPTTATVSSSEPAGRSPQSSAIAHPTKVYGKEQFLRMRQSMFPDR
What is the function of this protein?
Beta-carboxysome assembly initiates when soluble RuBisCO is condensed into a liquid matrix in a pre-carboxysome by the RbcS-like domains of probably both CcmM58 and CcmM35.  CcmN interacts with the N-terminus of CcmM58, and then recruits the CcmK2 major shell protein via CcmN's encapsulation peptide.  Shell formation requires CcmK proteins and CcmO.  CcmL caps the otherwise elongated carboxysome.  Once fully encapsulated carboxysomes are formed, they migrate within the cell probably via interactions with the cytoskeleton.
What are the official names of this protein?
Carboxysome assembly protein CcmN, Carbon dioxide concentrating mechanism protein CcmN, ORF I.
What is the protein family that this protein belongs to?
Belongs to the CcmN family.
What are the subcellular locations of this protein?
Carboxysome. Note=This cyanobacterium makes beta-type carboxysomes.
Protein: KGUA_HALH5
Sequence: MEKEKGLLIVLSGPAGVGKGTVCSALRKHDTNIQYSVSATTRAPRKGEVDGVNYFFKSREQFEAMIEKEELLEWAEYVGNYYGTPIQYVRETIDSGKDIILEIEVQGALKVRERFPEGVFIFLMPPSLAELRSRIVGRGTETEEVINKRMNVAKEEIEMMKKYDYVVENDEVELAVDRIKAIVTAEHCKRERLIEKYHQLVEVE
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
Protein: YJGA_ECO45
Sequence: MTKQPEDWLDDVPGDDIEDEDDEIIWVSKSEIKRDAEELKRLGAEIVDLGKNALDKIPLDADLRAAIELAQRIKMEGRRRQLQLIGKMLRQRDVEPIRQALDKLKNRHNQQVVLFHKLENLRDRLIDQGDDAIAEVLNLWPDADRQQLRTLIRNAKKEKEGNKPPKSARQIFQYLRELAENEG
What are the official names of this protein?
UPF0307 protein YjgA.
What is the protein family that this protein belongs to?
Belongs to the UPF0307 family.
Protein: YRUB_CLOPA
Sequence: MIKIYSTPTCPWCKKTKEYLKSKNIDFVDVNVADDMKEREEMRSLSKQSGVPVINIDGNIIVGFNKAEIDKLIEK
What are the official names of this protein?
Uncharacterized glutaredoxin-like 8.6 kDa protein in rubredoxin operon, ORF B.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family.
Protein: SRR1L_HUMAN
Sequence: MAAAAAAALESWQAAAPRKRRSAARRPRRREAAPRGREAAPRGREAAPRGPEAEFESDSGVVLRRIWEAEKDLFISDFWSSALETINRCLTKHLEQLKAPVGTLSDIFGNLHLDSLPEESDVATDSIPREILVTGTCHLKCVCYGIGNFATCIVARNQLTFLLLLLEKCQIPRSHCWVYDPLFSQLEIEVLNTLGVTVLSENEEGKRSIRGEPTIFYMLHCGTALYNNLLWSNWSVDALSKMVIIGNSFKGLEERLLARILQKNYPYIAKILKGLEELEFPQTSQYMDIFNDTSVHWFPVQKLEQLSIDIWEFREEPDYQDCEDLEIIRNKREDPSATD
What is the function of this protein?
Plays a role in the regulation of heme biosynthesis and in the regulation of the expression of core clock genes.
What are the official names of this protein?
SRR1-like protein, SRR1 domain-containing protein.
What is the protein family that this protein belongs to?
Belongs to the SRR1 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Also found in intracellular organelles.
Protein: VPS36_BOVIN
Sequence: MDRFVWTSGLLEINETLVIQQRGVRIYDGEEKIKFDPGTLLLSTHRLIWRDQKNHECCMAIPLSQIVFIEEQAAGIGKSAKIVVHLHPAASNKEPGPFQSSKNSYIKLSFKEHGQIEFYRRLSEEMTQRRWENMPVPQSLQTNRGPQPGRIRAVGIVGIERKLEEKRKETDKNISEAFEDLSKLMVKAKEMVELSKSIANKIKDKQGDITEDETIRFKSYLLSMGIANPVTRETYGSGTQYHMQLAKQLAGILQAPLEERGGIMSLTEVYCLVNRARGMELLSPEDLVNACKMLEALKLPLRLRVFDSGVMVIELQSHKEEEMVASALETVSEKGSLTSEEFAKLMGMSVLLAKERLLLAEKMGHLCRDDSVEGLRFYPNLFMTQS
What is the function of this protein?
Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.  The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation.  The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex.  Its ability to bind ubiquitin probably plays a role in endosomal sorting of ubiquitinated cargo proteins by ESCRT complexes.  The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL.  Binds phosphoinosides such as PtdIns(3,4,5)P3.
What are the official names of this protein?
Vacuolar protein-sorting-associated protein 36, ESCRT-II complex subunit VPS36.
What is the protein family that this protein belongs to?
Belongs to the VPS36 family.
What are the subcellular locations of this protein?
Cytoplasm. Endosome. Late endosome. Membrane. Nucleus. Note=Colocalizes with ubiquitinated proteins on late endosomes. Recruited to the endosome membrane to participate in vesicle formation.
Protein: NRDR_STRA3
Sequence: MRCPKCGYNKSSVVDSRQAEEGTTIRRRRECEKCGNRFTTFERLEELPLLVIKKDGTREQFSRDKILNGIIQSAQKRPVSSEDIENCILRIERKIRSEYEDEVSSITIGNLVMDELAELDEITYVRFASVYKSFKDVDEIEELLQQITKRVRSKKSGSV
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: NRDR_RALPJ
Sequence: MKCPFCGHAATQVIDTRMSEEGDTVRRRRRCESCDRRFTTYERIELFFPAVVKKNGSRVDYDRNKVKDSMRLALRKRPVSAEAIDEAIARIEEKLLSHGEKEIGSDRVGELVMRELKRLDKIGYIRFASVYRSFEDLAEFRDVLDEVAATNVRK
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: ERIL_HERER
Sequence: MSTTLQPLPGGLQVAVQACLFLGAVSRSRRFRALLFPPVLAMSLYMLLYTTTGKDSDDIVTWSLITTSLLQGSDILLINDVADLRLVGQKTPTNELSLWQRIKWAGRLMSAPRAVGFTHESRHVFPPHPPANEPRWTFIKRQSLTTLFYFVVLDLVHTFIVLSPVFQRDGVSLTSVDWPMRFLYTALHAAHLWSYMSFGYSAASVVLVALGVSDSDQWPAIYGDWSNAYTIRRFWGRVWHQVFRRIVSTHGDFVTYRFLALPKGTFFADNVHRYTAFFISGVIHAVGEYGMFRDQWLQKSGALRFFLLQATAILVEQEVGKIFKLQPTPLLRRLGYMWTFLWFVFTLPHWMDPQFRQGMADNYGFPLSVSYGLLKGQWRLVA
What is the function of this protein?
Acetyltransferase; part of the gene cluster that mediates the biosynthesis of erinacines, cyathane-xylosides that show unique biological activities, including leishmanicidal activity, stimulating activity for nerve growth-factor synthesis, and agonistic activity toward the kappa opioid receptor (PubMed:31535864).  The geranylgeranyl diphosphate (GGPP) synthase eriE catalyzes the first step in erinacines biosynthesis via conversion of farnesyl pyrophosphate and isopentyl pyrophosphate into geranylgeranyl pyrophosphate (GGPP) (PubMed:31535864).  GGPP is then substrate of the diterpene cyclase eriG for the production of cyatha-3,12-diene (PubMed:28371074).  EriG is unable to use geranyl diphosphate (GPP) or farnesyl diphosphate (FPP) as substrates (PubMed:28371074).  The cytochrome P450 monooxygenase eriI then hydroxylates cyatha-3,12-diene at C-14 of the seven-membered ring to produce erinacol, which is further hydroxylated at C-15 by the cytochrome P450 monooxygenase eriC to yield cyathadiol (PubMed:31535864).  The cytochrome P450 monooxygenase eriA then catalyzes C-11 hydroxylation in the presence of the short chain dehydrogenase/reductase (SDR) eriH, which leads to the production of cyathatriol (PubMed:31535864).  The acetyltransferase eriL converts cyathatriol into 11-O-acetyl-cyathatriol (PubMed:31535864).  The SDR eriH catalyzes further oxidation of 11-O-acetyl-cyathatriol into 1-O-acetylcyathin A3 (PubMed:31535864).  Finally, the glycosyl transferase eriJ tranfers xylose from UDP-xylose onto C-14 of 11-O-acetyl-cyathatriol to form eracine Q (PubMed:31535864).  EriJ is also able to convert 11-O-acetyl-cyathatriol to eracine Q2 by using UDP-D-glucose as cosubstrate, but at a lower rate (PubMed:31535864).  In the absence of eriL and eriJ, the SDR eriH is able to convert cyathatriol to cyathin A3; this is likely a switching mechanism in the biosynthesis of cyathins (C-14 ketogroup)and erinacines (C-14 glycosylated group) (PubMed:31535864).  The roles of the SDR eriB, the polyprenyl transferase eriF and the dehydrogenase eriK have still to be identified (Probable).
What are the official names of this protein?
Acetyltransferase eriL, Erinacine biosynthesis cluster protein L.
What is the protein family that this protein belongs to?
Belongs to the wax synthase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MRAY_PROMH
Sequence: MLVWLAEYLVKYHTFFNVFSYLTFRAIVGLLTALIIALWMGPHLIAWLQKMQIGQVVRNEGPESHFSKRGTPTMGGIMILFSIAVSTLLWARLDNPYVWCVLLVLIGYGIIGFIDDYRKVVRKDTRGLIARWKYFWQSVLALAVAFSMYAIGKDTPATQLVVPFFKDVMPQLGMLYILLAYFVIVGTSNAVNLTDGLDGLAIMPTVFVAAGFALVAWATGNVNFASYLKIPYLMHAGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGTIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISLMLVLIGLATLKVR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RRAAH_BURP1
Sequence: MMFATTDLCDAHEDRLAAGTLRVLEPVFRPFGGVRRFAGPAATLKLFEDNSLVRTALEQDGAGRVLVVDGGGSLRCALVGGNLGKLAEKNGWAGIVVNGCVRDSDELAECRVGVLALAAHPRKSDKRGAGVSDAPVDVRGTRIVPGDWIYADADGVLVSDDALLE
What is the function of this protein?
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.  Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
What are the official names of this protein?
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase, HMG aldolase, Oxaloacetate decarboxylase, OAA decarboxylase, Regulator of ribonuclease activity homolog, RraA-like protein.
What is the protein family that this protein belongs to?
Belongs to the class II aldolase/RraA-like family.
Protein: HIR3_CANGA
Sequence: MSSFSFLNQSPDIEQLEAEEHTRETQIELCFQLFQDALERLKDDKFGDANDLFEKLMSQEVIKPDKWGLYAYSSSIVDNLRYLAYRNRGFFYYKFLMNQYSESMSSEDVVDNILKIVENLLESLRHSEADYNVIEVLVQIFESFKSKRLQKLLLENEFMNNDSHLLFSGRKRTNILPQLKVLISQYINLLKDLHASSVLEKKIICNGQAKNTSHLPRTNVKFKNILEQLNKLRTEDDELIKSLDIHDIELDNYDWTSLLRSLRETLPTVKSLALFGRNSDPYAETETPIEAVKVIVKEEVVIDKIHDNSNNENEVTEEKEITDNKVVTTNGNNRKRSITEIETKHAQRSSKRFRDRDSSAADSETPMTFEPMFYSYTKILSLLGCKAPYDYEAIYPDLMEVKANDIIYADFLACLKEWSHWHTDCLSSQNEKEIKTKKVESSTDVSLSHFKTLLNSKNFQKSDDHIPEISQTSLRRFLDKVNRQQCHFHELRFKLIWFLFDNQNGDRLLTSTRWTKQMYRDVEWITLSIEKNIFSFIQSDIAKYRHVALSIFETLINSLVELCEEINSKLSLGQKANDQKTQKVKIEKKITKWNSIIAQVETTDRDWTVRYLWAYYTLIQCTSDIQNCLLSNILEKVHQILMKDNSSTVYLYPNADFISSFDLSFVDTQLKKLKMIKKLVNVDKHSESDKSEDNNSQFIMLENVLLSTISENHAVGGDDDDMIDFFMSAPFMLKFKLWELIYMKYVKKNDIEKTTLIYGIMLKLLVDTLECKTYRTLGPKKRQERLLIMMSCLKDITHNCIEVLKNNAWLQKKLSWYDDTTSQLVFIFFILFPMLPVNTPNKLSGTQTFFQKATKSSKTIKSIFVDILTLLLFHLNIGLKSKISSEPELENSIIDLVSTTHISISFYNFCDYASGNFLQIAENLICQFTNEEAFTQLKQIMWCKYHYQLSGDSSIVSQHKTKAMEMSKMVSLPLGIYLVKLQYQDKHPYINSAKIASKQILDNIVETFGDLSSQDNYIIMRNLHAFNGYLRSNITSKLFQSCFEGKDKVDLKNPNDEFQKAMDAGVFYVSGIQALNLYKIRKRSVQARPSELDAIITMFKNDILYNTKRFESWYLLGKCYSYIVEDDLLWTADKISSSEKKAVIATTQKRAILCYAMSLTLFFENETTRTVDEQIVIVECLESLANELMIAVYKPMEALCFDTNLSSLVVSSSNPATSSEIEKSSVAPIYSITDSSIEDTMIKCLTLANRYQESLLEAGKLDRLNWFNFYSIAIVYSTEKLDRKGDMIDNMSKACELANKYTSVKDSVVEPHVALIHMLYKLYIEGKVTMEDTLSTLKRDKFFEGFDDDFWILDVSLTQDYQKREFFSKLIELLKYVISKDKKKWQHEPYFYIAEILFMEMKDVEKSREWMDNIISIRSVNKNLVNIWKPDYERPGKHFVFTHNYVMFYLELLKYDKDAQSIGLLTKKLRRFSSGMAYIGKANDVATSYFIECVTKKYLLHDKVYTESYMGNINYNDFVKYSQEIVDNSKAADIAEDILEVLKIAYQLKKGTNSVVYDTVCLSLFFQYIYEPYRKEHPETEPQLVSDSENKSNIRKKVSKKDAFDKIRALVDKLP
What is the function of this protein?
Has a role in a nucleosome assembly pathway that is required for the integrity of heterochromatin and proper chromosome segregation.
What are the official names of this protein?
Histone transcription regulator 3 homolog.
What is the protein family that this protein belongs to?
Belongs to the HIR3 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KDSA_GLAP5
Sequence: MQQKTISLGNIDIANDKPFVLFGGMNVLESRDMAMQVCEKYVEVTQRLGVPYVFKASFDKANRSSIHSYRGPGMEEGLKIFQELKDTFGVKIITDVHEIYQCQPVAEVVDIIQLPAFLARQTDLVEAMARTGAVINVKKPQFLSPGQMGNIVEKIEECGNDKVILCDRGTNFGYDNLVVDMLGFNVMKKVSKGCPVIFDVTHSLQCRDPFGAASGGRRDQVTKLARAGMAIGLAGLFLEAHPDPNKAKCDGPSALPLSKLEAFVSQMKAIDDLVKSFEEIDTSN
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELO_STUS1
Sequence: MKTLTQLHFDNRFARLGDTFSTQVSPQPLEAPRLVVASEAAMALLDLDPAEAEQALFAELFSGHKIWSTAEPRAMVYSGHQFGSYNPQLGDGRGLLLGEVVNEAGEYWDLHLKGAGKTPYSRMGDGRAVLRSSIREFLASEHLHALGIPSSRALCVTGSDTLVYRERPERGAMLLRLAPSHVRFGHFEFFYYTRQHGELKQLLEHVIEVHFPELLEHPEPFHMFFRTVLERTAALIARWQAYGFCHGVMNTDNMSILGITFDFGPYAFLDDFDARFICNHSDDTGRYSFENQVPIAHWNLAALAQALTPFVEVKVLRETMELFLPLYEAEWLDLMRRRLGFSQAEDGDAELIRRLLQLMQGSAVDYTRFFRELGERPAEQAVQRLREDFIDLQGFDAWAADYCARSAREGGDPVARQARMHAVNPKYILRNYLAQQAIEAAEKGDYAPVRELHAVLSRPFDEQPGMERYAERPPEWGKHLEISCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: NSP3_ROTBS
Sequence: MATQASVEWIFNVAGSAASASLAKSIKDAGGSEDFAKYVVARFYDNYKDSIDDSGIYNACMGRARTVDKALNDSRLAERNEEWHTNLATIRRLDLELAELKLMLSNLGMKREERVLNSMFSVTREEGRSSNVVMLKQNAVKMIEEGKLKIKVEKNENYTESLKNKIEELECIIGAFEKGKEINIALDAMTGEVRLDGDSCSYNSTAAFVSTIMGTPIKMYDESNKPLFDVGKYINPKHVIDKMIESEIPIFKSDYRNNESPDFDAWNENSNLKIVSVNDCHAICVFKFENEWWCFDDGRLRKYNGIGNPLIVANSKFQIDRILISGDIELNPGPNALVKLNDCITKYNLKIICTFDVNLDDDGSIMYICYLKVGSAEATGNGCSKKEAKRRAAVSILDQLGM
What is the function of this protein?
May play a role in stimulating the translation of viral mRNAs.
What are the official names of this protein?
Non-structural protein 3, NSP3, NCVP4, Non-structural RNA-binding protein 34, NS34.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP3 family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: IF3_THETH
Sequence: MKEYLTNERIRAKQVRVVGPDGKQLGIMDTREALRLAQEMDLDLVLVGPNADPPVARIMDYSKWRYEQQMAEKEARKKAKRTEVKSIKFRVKIDEHDYQTKLGHIKRFLQEGHKVKVTIMFRGREVAHPELGERILNRVTEDLKDLAVVEMKPEMLGRDMNMLLAPVKVSA
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCSA_OENAR
Sequence: MIFYTLEHILTHISFSLVSIGITIFLITLSVDEIIGLYDSSEKGVIGTFLCITGLLVTRWAYSGHFPLSNLYESLLFLSWSFAIIHMFPYLKKQKSYVRTITSSSTIFTQGLVTSGLLSEMQQSEILVPALQSQWLMMHVSMMVLGYAALLCGSLLSVALLVITFRKALKIFSKKKAFLKDSFSFVEIQYRNEPSNVLLSTSFISSKNYYRAQLIQQLDRWSSRIISLGFIFLTIGILSGAVWANEAWGSYWNWDPKETWAFITWTMFAIYLHTRTNPNFQSVNSAIVAFLGFIIIWICYFGVNLLGIGLHSYGSFNLH
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RS8_METPP
Sequence: MSMSDPIADMLTRIRNAQMVEKAVVVMPSSKLKVAIAQVLKDEGYIDAYAVKGEAEKPQLEIGLKYYAGRPVIERIERVSRPGLRVYKGRHEIPQVMNGLGVAIVTTPKGVMTDRKARAAGIGGEVLCYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: CYB_INDPA
Sequence: MASLRKTHPLLKIVNDNSIDLPTPQNISAWWNFGSLLGLCLVAQILTGLFLAMHYTPDINAAFSSVAHICRDVNHGWLIRNLHANGASFFFLCLYLHIGRGLYYGSYLNKGTWNTGILLLLLIMVTAFVGYVLPWGQMSFWGATVITSLLSALPYVGTDLVQWLWGGFSVDNATLTRFFAFHFFIPFIATAVVALHFLFLHETGSNNPTGLSSSADKVPLHPYFLYKDLLGFLLLLAPLTALAVFSPNLFGDPDNFLRANPMVTPTHIKPEWYFLFAYAILRAIPNKLGGVLALLASILVLAVVPFLHTSKQRSLALRPWSQLCLFTLVVTVLILTWIGGMPLEQPLTTVGQIASLLYFTIILFLMPMLGLIENKMLN
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ACDE2_METMA
Sequence: MVDTTKNTKLFTSYGVSTSKTVAPEMAAKLISKAKRPLLMVGTLALDPEILDRVVKISKTANIPIAATGSSLAALADKDVDAKYINAHMLGFYLTDPNWPGLDGNGNYDMVISIGFKKFYINQVLSAAKNFSNVKAIAIERGYIQNATMSFGNLSKAEHYAALDELVDFL
What is the function of this protein?
Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy.  The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.  The precise role of the epsilon subunit is unclear; it may have a stabilizing role within the alpha(2)epsilon(2) component and/or be involved in electron transfer to FAD during a potential FAD-mediated CO oxidation.
What are the official names of this protein?
Acetyl-CoA decarbonylase/synthase complex subunit epsilon 2, ACDS complex subunit epsilon 2, ACDS complex carbon monoxide dehydrogenase subunit epsilon 2, ACDS CODH subunit epsilon 2.
What is the protein family that this protein belongs to?
Belongs to the CdhB family.
Protein: F16PA_SULNB
Sequence: MHTIFETIEKVALKIDHAIKTEDLGYSESENSSGEDQLKLDVKSDYLIEEAFKSVSLVKDLISEEKEGVMPLHSNGKYTICYDPLDGSSLADVNLSVGSIFGIYDGEPKGENLVASAYVVYGPRIEIIRAVKGERPKHYRAQDGFFNLVSKEVILKEKGKLNAPGGTQQNWCDYHKSFVDDLFAEGYRLRYSGGMVPDLHQILLKGGGIFSYPGTSDKPHGKLRQLFEVIPFAFIYEQAGGQAIDAKGKRLMELVPAHPHDTSPCFFGSNYEIKALKKAYGVNA
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_STAAC
Sequence: MISKIDKNKVRLKRHARVRTNLSGTAEKPRLNVYRSNKHIYAQIIDDNKGVTLAQASSKDSDIATTATKVELATKVGEAIAKKAADKGIKEIVFDRGGYLYHGRVKALAEAARESGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RL9_STRPI
Sequence: MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAVGELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAEELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.