PharMolix/UniProtQA huggingface dataset:
Protein: DMC1B_ORYSJ
Sequence: MAPSKQYDEGGQLQLMDAERIEEEEECFESIDKLISQGINSGDVKKLQDAGIYTCNGLMMHTKKSLTGIKGLSEAKVDKICEAAEKLLSQGFMTGSDLLIKRKSVVRITTGSQALDELLGGGIETLCITEAFGEFRSGKTQLAHTLCVSTQLPIHMHGGNGKVAYIDTEGTFRPERIVPIAERFGMDANAVLDNIIYARAYTYEHQYNLLLGLAAKMAEEPFRLLIVDSVIALFRVDFSGRGELAERQQKLAQMLSRLTKIAEEFNVAVYITNQVIADPGGGMFITDPKKPAGGHVLAHAATIRLMLRKGKGEQRVCKIFDAPNLPEGEAVFQVTSGGIMDAKD
What is the function of this protein?
Recombinase that may participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks (By similarity).  Exhibits DNA-dependent ATPase activity when bound to single-stranded DNA (ssDNA).  Mediates renaturation of homologous complementary strands as well as assimilation of single strands into homologous supercoiled duplexes leading to D-loop formation (By similarity).  Binds circular single-stranded DNA (ssDNA) and circular double-stranded DNA (dsDNA) in vitro (By similarity).  Catalyzes DNA homologous renaturation and DNA strand exchange.  The rates of these activities are dependent on the state of ATP hydrolysis (By similarity).  Forms helical filaments along ssDNA and dsDNA, and promotes strand exchange between ssDNA and dsDNA with long DNA substrates of several thousand base pairs.  The presence of the replication protein A is not required for this activity (PubMed:18583359).  Seems to be required for homologous pairing and subsequent chromosome segregation during male meiosis (By similarity).  May be not directly required for homologous pairing during male meiosis.  Required for synaptonemal complex assembly and crossover formation.  Functions redundantly with DMC1A (PubMed:26960731).
What are the official names of this protein?
Meiotic recombination protein DMC1 homolog B, OsDMC1B, RiLIM15B.
What is the protein family that this protein belongs to?
Belongs to the RecA family. DMC1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CBY1_MOUSE
Sequence: MPLFGSIFSPKKTPPRKSASLSNLHSLDRSTRELELGLDYGTPTMNLAGQSLKFENGQWVADSVISGGVDRRETQRLRKRNQQLEEENNLLRLKVDILLDMLSETTAESHLKDKELDELKVTNRRRK
What is the function of this protein?
Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors.  Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins.  Promotes adipocyte and cardiomyocyte differentiation.
What are the official names of this protein?
Protein chibby homolog 1, Cytosolic leucine-rich protein, PIGEA-14, PKD2 interactor, Golgi and endoplasmic reticulum-associated 1.
What is the protein family that this protein belongs to?
Belongs to the chibby family.
What are the subcellular locations of this protein?
Nucleus speckle. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Golgi apparatus. Golgi apparatus, trans-Golgi network.
Protein: INO80_CANGA
Sequence: MSLSALLNNDDPVEDTKLYLESLNREMDRLIKRDQLELMYQDWKFANYQEFELISEWNTQCKELVGDGNDLQNNDLMTEEVHLDDLYDNIQRIRNEWKDYESYKETRSQLLSKSIQAKPIKHRRRRRTKLEMEAAANLAALSQMGTTDVKTPEIINDHGNRSKASRSDTTNKTDNTMAGINSPTSDVDSGHKDELDQTKLIKKQEASSSTNSAASVTASVANGIVEDQKDEAERTIEANRIGSNMQNSDQDTMDDLKKTNDPSSDIDSDANTSVNDGSDENLSNKLDSDDLHSEPADNEEEPVSSDAEKDQAENINQTDESEEEIIVKEYDDNNDEDFAPEIKKPKPNGKIVTINSDRPKIVRELIKLRNKGKAPKSSKRRYTAVNITEYSPTEKKISVKITLKQMHVKKLKKILQDARKAEEKRLQEEAKQIADQESPRKRRKIDRSENTKQEDEDDKEDDDLDGLPTYGMKMSLKDAKAIQRHYDNTYTMIWKDMARKDCMKISRLVQQIQSTRALNYKKTSSLCAREARKWQTRNFKQVKDFQTRARKGIREMANFWKKNEREERDLKKKAEREALELAKKEEEEKESKRQAKKLNFLLTQTELYSHFIGRKIKTSALEGNEVAEEDEDNYDLTTTAPNKNDFHAIDFDNENDEQLKLKAAQNASNALAETRAKAKAFDDAHRQQQSTESDDEEEMNFQNPTSLGEITIEQPKMLACTLKEYQLKGLNWLANLYDQGINGILADEMGLGKTVQSISVLAHLAEHHNIWGPFLVVTPASTLHNWVNEISKFVPQFKILPYWGSANDRKVLRKFWDRKNLRYSEKSPFHVMITSYQMVVADASYLQKMKWQYMILDEAQAIKSSQSSRWKNLLSFHCRNRLLLTGTPIQNNMQELWALLHFIMPSLFDSHDEFNEWFSRDIESHAEGNSSLNQQQLRRLHMILKPFMLRRIKKNVQSELGDKIEIDVMCDLTQRQTKLYQVLKSQMSSNYDAIENAAAEGSDIAGGGNSDQSIINAVMQFRKVCNHPDLFERADINSPFSFTSFGKTSSLISSSIATSGGLTETISELMYSSTNPINCAIPKLIYEDLILPNYNNSIDIMEKLLLSDFSIYDPVNNKEMCQYLGLLTGLAYGSFRKIHKSNYFERIINLKKESKQSSQNLITVVSNANDLIADSIVHADTNLPNLTGIRNDIYHNDYLNSIQPGYCPKVVAPPINFNVNGSLNFTNKMSSYLFNPVITTALSSIPPPTQYNMFVKKCIPIEEFPISEMYPNPLNKHFSSNISMPSMDRFITESAKLKKLDELLVELKKNDHRVLIYFQMTKMMDLMEEYLTYRQYNHIRLDGSSKLEDRRDLVHDWQTNPEIFIFLLSTRAGGLGINLTAADTVIFYDSDWNPTIDSQAMDRAHRLGQTKQVTVYRLLVRGTIEERMRDRAKQKEQVQQVVMEGKTKDTNIQTTHTRPEHEQLTPKSLSSEPEATNNLITVKN
What is the function of this protein?
ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
What are the official names of this protein?
Chromatin-remodeling ATPase INO80.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: POTA_LISMF
Sequence: MIVTETIIRFENVTKQFDNDPPVLDNVSFEIEKGKFYTLLGPSGCGKTTILRLIAGFLEASEGQIYLGDKVINQIPANKRPVNTVFQDYALFPHLNVYENVAFGLRIKKLKKDAIDEKVKEALRFVNLKGYEKREISEMSGGQRQRVAIARAIVNEPEVILLDEPLSALDLKLRTEMQYELRDLQKRLGITFIFVTHDQEEALAMSDEIFVLNKGEIQQSGTPIDIYDEPINKFVADFIGESNIVNGKMIQDFEVEFVERRFECVDQGFRPNEVVEVVIRPEDLEITSAEKGQLQVTVDWMLFRGVHYEVGCIDTDGNEWLVHTTRKVRVGDKIGLAFEPEAIHVMRLGETEEEFDKRLDSYDEVQ
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TX813_LYCSI
Sequence: MKLIIFTGLVLFAIVSLIEAQAENEKACLPQYQVCTDAPGNCCSNVVCDCYGRYKSGARIGRNCFCLQKGVIYKREN
What are the official names of this protein?
U8-lycotoxin-Ls1d, Toxin-like structure LSTX-H13.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 08 (U8-Lctx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RMF_TOLAT
Sequence: MKRQKRDRLERARTKGYQAGLAGRSKELCPYQCIDARGYWLGGWRDAVDERSQGYMVN
What is the function of this protein?
During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes).
What are the official names of this protein?
Ribosome modulation factor, RMF.
What is the protein family that this protein belongs to?
Belongs to the ribosome modulation factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSD_SALDC
Sequence: MDQKRLTHLRQLEAESIHIIREVAAEFANPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYAFRDRTANAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWRNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMVDDDRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESHAQTLPEIIEEMLVSTTSERQGRMIDRDQAGSMELKKRQGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: RL24_DESVM
Sequence: MKQFRIRKDDKVVVIAGKDKGKIGKVLKVLPKKDGVLVEKVNMVKRHMRANPYRQQPGGIIEKEMPLDISNVMVMCDACAKATKVGYRYTEDGKKVRFCKKCNEIIG
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: ZN304_HUMAN
Sequence: MAAAVLMDRVQSCVTFEDVFVYFSREEWELLEEAQRFLYRDVMLENFALVATLGFWCEAEHEAPSEQSVSVEGVSQVRTAESGLFQKAHPCEMCDPLLKDILHLAEHQGSHLTQKLCTRGLCRRRFSFSANFYQHQKQHNGENCFRGDDGGASFVKSCTVHMLGRSFTCREEGMDLPDSSGLFQHQTTYNRVSPCRRTECMESFPHSSSLRQHQGDYDGQMLFSCGDEGKAFLDTFTLLDSQMTHAEVRPFRCLPCGNVFKEKSALINHRKIHSGEISHVCKECGKAFIHLHHLKMHQKFHTGKRHYTCSECGKAFSRKDTLVQHQRVHTGERSYDCSECGKAYSRSSHLVQHQRIHTGERPYKCNKCGKAFSRKDTLVQHQRFHTGERPYECSECGKFFSQSSHLIEHWRIHTGARPYECIECGKFFSHNSSLIKHRRVHTGARSYVCSKCGKAFGCKDTLVQHQIIHTGARPYECSECGKAFSRKDTLVQHQKIHTGERPYECGECGKFFSHSSNLIVHQRIHTGAKPYECNECGKCFSHNSSLILHQRVHTGARPYVCSECGKAYISSSHLVQHKKVHTGARPYECSECGKFFSRNSGLILHQRVHTGEKPYVCSECGKAYSRSSHLVRHQKAHTGERAHECNSFGGPLAASLKLV
What is the function of this protein?
Acts as transcriptional regulator and plays a role in gene silencing (PubMed:24623306, PubMed:26081979).  Probably forms a corepressor complex required for activated KRAS-mediated promoter hypermethylation and transcriptional silencing of several tumor suppressor genes (TSGs) or other tumor-related genes in colorectal cancer (CRC) cells (PubMed:24623306).  Also required to maintain a transcriptionally repressive state of genes in undifferentiated embryonic stem cells (ESCs) by inducing trimethylation of 'Lys-27' of histone H3 (H3K27me3) (PubMed:24623306) in a Polycomb group (PcG) complexes-dependent manner.  Associates at promoter regions of TSGs and mediates the recruitment of the corepressor complex containing the scaffolding protein TRIM28, methyltransferase DNMT1 and histone methyltransferase SETDB1 and/or the PcG complexes at those sites (PubMed:24623306).  Transcription factor involved in the metastatic cascade process by inducing cell migration and proliferation and gain resistance to anoikis of ovarian carcinoma (OC) cells via integrin-mediated signaling pathways (PubMed:26081979).  Associates with the ITGB1 promoter and positively regulates beta-1 integrin transcription expression (PubMed:26081979).  Promotes angiogenesis (PubMed:26081979).  Promotes tumor growth (PubMed:24623306, PubMed:26081979).
What are the official names of this protein?
Zinc finger protein 304, KRAB-containing zinc finger protein.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Note=Associates with chromatin (PubMed:24623306).
Protein: GDF2_HUMAN
Sequence: MCPGALWVALPLLSLLAGSLQGKPLQSWGRGSAGGNAHSPLGVPGGGLPEHTFNLKMFLENVKVDFLRSLNLSGVPSQDKTRVEPPQYMIDLYNRYTSDKSTTPASNIVRSFSMEDAISITATEDFPFQKHILLFNISIPRHEQITRAELRLYVSCQNHVDPSHDLKGSVVIYDVLDGTDAWDSATETKTFLVSQDIQDEGWETLEVSSAVKRWVRSDSTKSKNKLEVTVESHRKGCDTLDISVPPGSRNLPFFVVFSNDHSSGTKETRLELREMISHEQESVLKKLSKDGSTEAGESSHEEDTDGHVAAGSTLARRKRSAGAGSHCQKTSLRVNFEDIGWDSWIIAPKEYEAYECKGGCFFPLADDVTPTKHAIVQTLVHLKFPTKVGKACCVPTKLSPISVLYKDDMGVPTLKYHYEGMSVAECGCR
What is the function of this protein?
Potent circulating inhibitor of angiogenesis.  Signals through the type I activin receptor ACVRL1 but not other Alks.  Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG.
What are the official names of this protein?
Growth/differentiation factor 2, GDF-2, Bone morphogenetic protein 9, BMP-9.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL32_BACLD
Sequence: MAVPFRRTSKTKKRLRRTHFKLQVPGMVECPNCGEMKLSHRVCKACGSYKGKDVKSN
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: Y049_MYCTU
Sequence: MDYTLRRRSLLAEVYSGRTGVSEVCDANPYLLRAAKFHGKPSRVICPICRKEQLTLVSWVFGEHLGAVSGSARTAEELILLATRFSEFAVHVVEVCRTCSWNHLVKSYVLGAARPARPPRGSGGTRTARNGARTASE
What are the official names of this protein?
Uncharacterized protein Rv0049.
Protein: S22AG_XENLA
Sequence: MEHLFDYVGHFGRFQAYLYFASAFQTISCGIHYLASVFIAVTPKFICRAPGNISTVLLPNASTLRLEDAWESWTSKDYLVVQQENGDIWELNQCSRLKREDASYLTYFYDGNKTLFSCSNGYHYDKSNLESSIVTEWDLVCDREWLAKLIQPIFMLGVLIGAVIFGDIADRVGRRPIIWITSTGQFLFGIAVAFTFDYYSFVIVRFLLAMVSSGYYVVVFVYLTEYVGIKARTWASMHVHAFFAVGVMIVSLVGFLVRTWWIYQIILSLTTLPFVLCCWMLPETPFWLYSQGKYKEVEKLIRTIEKWNKISTPCKLSELCPAQETHVDQPNTLKNHNVLDLFYNWSFARRTITVWLIWFTGSLGYYVFALNSVNLGGNEYLNLFLTGAVEIPSYIVACLGMDKIGRRNTLAPFLIISAVICGVIMLIPQDHSTVTIAMSMAGKFSIAVAFGLIYLYTAELYPTIVRSLAVGSGSMMCRIGSVVAPFCVYLTDVWIFMPQMLVGIMAFLTGILTLTLPETLGIPLTSTMEEAAEMGTTSGITKRKALTESNGVVMEKLDQTTDNAAS
What is the function of this protein?
High affinity carnitine transporter.
What are the official names of this protein?
Solute carrier family 22 member 16, Carnitine transporter 2, CT2.
What is the protein family that this protein belongs to?
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS10_MYCBO
Sequence: MAGQKIRIRLKAYDHEAIDASARKIVETVVRTGASVVGPVPLPTEKNVYCVIRSPHKYKDSREHFEMRTHKRLIDIIDPTPKTVDALMRIDLPASVDVNIQ
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RLMN_CITK8
Sequence: MSEQIVTSEIITPVVPDKNGKINLLDLNRQQMREFFKELGEKPFRADQVMKWMYHYCSDNFDEMTDINKVLRGKLKEVAEIRAPEVVEEQRSSDGTIKWAIAVGDQRVETVYIPEDDRATLCVSSQVGCALECKFCSTAQQGFNRNLRVSEIIGQVWRAAKIVGAAKVTGQRPITNVVMMGMGEPLLNLTNVVPAMEIMLDDFGFGLSKRRVTLSTSGVVPALDKLGDMIDVALAISLHAPNDEIRDEIVPINRKYNIETFLDAVRRYLQKSNANQGRVTIEYVMLDHINDGTEHAHQLAELLKDTPCKINLIPWNPFPGAPYGRSSNSRIDRFSKVLMSYGFTTIVRKTRGDDIDAACGQLAGDVIDRTKRTLRKRMQGEAIDIKAV
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX1_ALLMA
Sequence: MFQRNTVYRWLFSTNAKDIGTLYLVFSIFAGMIGTAFSVLIRFELAGPGVQYLYGDHQLYNVIITAHAFIMIFFLVMPAMLGGFGNYFVPIMIGAPDMAFPRLNNISFWLLPPSLILLVGSAFVEQGAGTGWTVYPPLSSIGFHSGGSVDLAIFSLHLAGISSMLGSINFITTILNMRAPGMTMHKLPLFVWSILITAILLLLSLPVLAGAITMLLTDRNLNTTFYDPAGGGDPVLYQHLFWFFGHPEVYIIIIPGFGIISQVISTFSRKPIFGYLGMVYAMASIGILGFIVWSHHMYTVGLDVDTRAYFTAATMIIAVPTGIKIFSWLATLYGGNILYRTPAYFALGFLFLFTIGGVTGVMLANASLDVALHDTYYVVAHFHYVLSMGAVFALFAGFYYWIGKITGKQYNEFWGQVHFWTMFIGVNVTFFPMHFLGLNGMPRRIPDYPDAFTQWNVISSFGSIISIVSTIVFLYGLYLTLSQPAVSLANNYWHVPSFFSSTHSLYGDTTQTSSSLEWVLPSPPAFHAFNHLPVQS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RM34_MOUSE
Sequence: MAFLARCFGCQACRSVALLSGRYLQSRVWMGLPDSWPLLSLQQARGRARGNEYQPSNIKRKHKHGWVRRLSTPAGVQVILRRMLKGRKSLSH
What are the official names of this protein?
39S ribosomal protein L34, mitochondrial, L34mt, MRP-L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RS3_METHJ
Sequence: MAVERKFVADGVRKVRVERHLGHELKRAGYGGMDLIRTPLGTQVTIFAEKPGIVIGKGGKVVRTLTQDLATTYGVESPQIEVQQVDNPNLNAQIMAERLASALERGWYFRKAGSSTLRRIMDSGALGCEVVISGKLTGARGRVQKFTEGYIKHSGDPVNTLVDKGYAVAIKKLGVIGVQVRLIPPGAQLPDHFEVTAAVTKKQRNMAHITRIPSEYDEEDLDLDAIVNEPDDFMEEE
What is the function of this protein?
Binds the lower part of the 30S subunit head.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RN152_CHICK
Sequence: METLSQDSLLECQICFNYYSPRRRPKLLDCKHTCCSVCLQQMRTSQKDLRCPWCRGITKLPPGYSVSQLPDDPEVIAVIAIPHTSEHTPVFIKLPSNGCYMLPLPLSKERAMLPGDIGCRLLPGSQQKSLAVVTIPAEQQPLQGGLPAEAGAEEPDRRGVVKSSTWSGVCTVILVACVLVFLLGIVLHNMSCISKRFTVISCG
What is the function of this protein?
E3 ubiquitin-protein ligase mediating 'Lys-63'-linked polyubiquitination of RRAGA in response to amino acid starvation.  Thereby, regulates mTORC1 signaling and plays a role in the cellular response to amino acid availability.  Also mediates 'Lys-48'-linked polyubiquitination of target proteins and their subsequent targeting to the proteasome for degradation.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF152, RING finger protein 152, RING-type E3 ubiquitin transferase RNF152.
What is the protein family that this protein belongs to?
Belongs to the RNF152 family.
What are the subcellular locations of this protein?
Lysosome membrane; Single-pass membrane protein.
Protein: Y1753_CLOAB
Sequence: MEERIYLSMLLSTYGSLLTEKQVNVMRLYYDDDLSMPEIAELNNTTRQAIHDLIKRCHKMLLNYENKLKLVEKYKRNEDIKKDIKDKLYILKDKIQDKDNVQLIDEIEKDINSFSI
What is the function of this protein?
Might take part in the signal recognition particle (SRP) pathway.  This is inferred from the conservation of its genetic proximity to ftsY/ffh.  May be a regulatory protein (By similarity).
What are the official names of this protein?
UPF0122 protein CA_C1753.
What is the protein family that this protein belongs to?
Belongs to the UPF0122 family.
Protein: ARGJ_ARATH
Sequence: MHSCSHTHFVSFKLPHFFAPKSFVVSSRRELRVFAVATTVEEASGNIPAAPISLPQGSWKQIAGGVTAAKGFKAAGMYAGLRAAGKKPDLALVTCDVEAVAAGVFTTNVVAAAPVVYCKKVLETSKTARAVLINAGQANAATGDAGYQDMLDCVGSIATLLKVKPEEVLIESTGVIGQRIKKEELLHALPTLVNSRSDSVEEADSAAVAITTTDLVSKSVAVESQVGGIKIRVGGMAKGSGMIHPNMATMLGVITTDALVESDIWRKMVKVAVNRSFNQITVDGDTSTNDTVIALASGLSGSPSISSLNCKEAAQLQACLDAVMQGLAKSIAWDGEGATCLIEVTVKGTETEAEAAKIARSVASSSLVKAAVYGRDPNWGRIAAAAGYAGVSFQMDKLKISLGEFSLMESGQPLPFDRDGASNYLKKTGEVHGTVTIDISVGDGAAIGKAWGCDLSYDYVKINAEYTS
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: THII_SALDC
Sequence: MKFIIKLFPEITIKSQSVRLRFIKILTGNIRNVLKHYDETLAVVRHWDNIEVRAKDENQRLAIRDALTRIPGIHHILEVEDVPFTDMHDIFEKALAQYREQLEGKTFCVRVKRRGKHEFSSIEVERYVGGGLNQHIESARVKLTNPDVTVHLEVEDDRLLLIKGRYEGIGGFPIGTQEDVLSLISGGFDSGVSSYMLMRRGCRVHYCFFNLGGAAHEIGVRQVAHYLWNRFGSSHRVRFVAINFEPVVGEILEKVDDGQMGVVLKRMMVRAASKVAERYGVQALVTGEALGQVSSQTLTNLRLIDNVSDTLILRPLISYDKEHIINLARQIGTEDFARTMPEYCGVISKSPTVKAIKAKIEAEEENFDFSILDKVVEEANNVDIREIAQQTQQEVVEVETVSGFGPNDVILDIRSVDEQDDKPLKVEGVDVVSLPFYKLSTKFGDLDQSKTWLLWCERGVMSRLQALYLREQGFENVKVYRP
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EI04_LITRU
Sequence: FITVH
What are the official names of this protein?
Electrin-4.
What are the subcellular locations of this protein?
Secreted.
Protein: Y6463_DICDI
Sequence: MKNNQTNQIKKRKLPYQIDKFKVQKFHHFQPNPITNSIEPLLDGSNNNKNNNYKKLKKMNYISTTTITTTNNIDLNNLLPIENIKQLFNQLNSNREIMDTLFNQFLQLYNSINFQSPLSNLSLLPITNYSNNDNDYNSNNIISTNIEGNNNNKSFILPNLNEDLFLNIPDSLKDLTNEKSIQENITLPTLENDLHSPLNLIQQFDQIINK
What are the official names of this protein?
Putative uncharacterized protein DDB_G0280241.
Protein: CTEN3_CUPSA
Sequence: MKHLIPLIVMASVVLAVYADRGYGGGRRGGGYGGGGYGGGGGGYGGGGGGYGGGVGGGRGGGGGLGGGRGGGGGVIDGKDDVGLGGGGYGGGLGGGQGGGGGLGGGQGGGGGLGGGRGGGGYGGGGGGYGGGKYGGGKYGRK
What is the function of this protein?
Antimicrobial protein with bacteriostatic activity against the Gram-negative bacterium E. coli, and very weak activity against the Gram-positive bacterium S. aureus.  Lacks activity against the yeast C. albicans.
What are the official names of this protein?
Ctenidin-3.
What are the subcellular locations of this protein?
Secreted.
Protein: RFA2B_XENLA
Sequence: MWNNQGGFDGGSGMGGGGYMQSPGGFGSPAPTQGEKKSRSRSQQIVPCTVSQLLSATQNDEVFRIGETELSQVIIVGIVRHAEKAPTNILYKVDDMTAAPMDVRQWVDTDEASCENMVVPPGSYVKVAGHLRSFQNKKSVVAFKIAPVDDMNEFVSHMLEVVHSHMVMNSQGAPSGGGSTMALNTPGRMGIGDSGGAFSGGNDNPTNGLTPHQNQILNLIKSCKGNEGMAFEELKNRLHGMNVNSIRKTVDFLSNEGHIYSTIDDEHYKSTDGD
What is the function of this protein?
As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress.  It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism.  Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage (By similarity).
What are the official names of this protein?
Replication protein A 32 kDa subunit-B, RP-A p32, Replication factor A protein 2, RF-A protein 2, Replication protein A 34 kDa subunit, RP-A p34.
What is the protein family that this protein belongs to?
Belongs to the replication factor A protein 2 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, PML body. Note=Redistributes to discrete nuclear foci upon DNA damage in an ATR-dependent manner.