PharMolix/UniProtQA huggingface dataset:
Protein: SAMH1_XENLA
Sequence: MKGINGAKRVRHDASPSAQDGYVTPEKRVKRWSGGQTAANYREWDVEEVCLFLASHGLGELEVIFRENKIKGRILEYLTDSHLKDLQISSVALRLDLLSCLRMLCQNSPSIMKVFNDPIHGHIELHPLLVRIIDTPEFQRLRYIKQLGGSYYVFPGASHNRFEHSIGVGYLAGCLVQALHERQPDLQIDMRDMLCVQIAGLCHDLGHGPFSHMFDGRFMPLACPQKKFKHESASVAMFDHLIQSNGLEEAMKENGLCLPDDLTFIKEQIAGPLSSEAEQQFNSSPNSSSWPYRGRTEEKSFLYEIVANKRNGIDVDKWDYFARDCHHLGIQNNFDYKRFLKFARVCEVGSKKHICTRDKEVGNLYDMFHTRNCLHRRAYQHKVGNIIETMITDAFVKADPHIKIEGANGKYYSISGSVDDMVAYTKLTDNIYHQILYSNDPNLKEAREILQKVERRHLYKYIGQTHPHSNSRIEPDKYDKLPADLASSVPQTSAKDVELHAEDFIVDVIHMDYGMKEQNPINNVRFYCKADPRKAIKIRRDQVSQLLPEKFAEQIIRVYCKKTDEKSLETAKRYFIQWCMNKDFSKPQDGDVVAPDMTPLKASWVDDDDDEDNEGKQQTELLHKSRVKLFTN
What is the function of this protein?
Protein that acts both as a host restriction factor involved in defense response to virus and as a regulator of DNA end resection at stalled replication forks (By similarity).  Has deoxynucleoside triphosphate (dNTPase) activity, which is required to restrict infection by viruses: dNTPase activity reduces cellular dNTP levels to levels too low for retroviral reverse transcription to occur, blocking early-stage virus replication in dendritic and other myeloid cells (By similarity).  Functions during S phase at stalled DNA replication forks to promote the resection of gapped or reversed forks: acts by stimulating the exonuclease activity of mre11, activating the ATR-CHK1 pathway and allowing the forks to restart replication (PubMed:29670289).  Ability to promote DNA end resection at stalled replication forks is independent of dNTPase activity (PubMed:29670289).
What are the official names of this protein?
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, dNTPase.
What is the protein family that this protein belongs to?
Belongs to the SAMHD1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localizes to sites of DNA double-strand breaks in response to DNA damage.
Protein: TPL_SYMTH
Sequence: MQRPWAEPYKIKAVEPIRMTTREYREQAIREAGYNTFLLRSEDVYIDLLTDSGTNAMSDRQWGALMMGDEAYAGARSFFRLEEAVREIYGFKYVVPTHQGRGAEHLISRILIKPGDYIPGNMYFTTTRTHQELQGGTFVDVIIDEAHDPQASHPFKGNVDIAKFEALIDRVGADKIPYINVALTVNMAGGQPVSMANLREVRKVCDRHGIRMWSDATRAVENAYFIKEREEGYQDKPVREILKEMMSYFDGCTMSGKKDCLVNIGGFLAMNEEWILQKAREQVVIFEGMPTYGGLAGRDMEAIAQGIYEMVDDDYIAHRIHQVRYLGEQLLEAGIPIVQPIGGHAVFLDARAFLPHIPQDQFPAQALAAALYVDSGVRAMERGIVSAGRNPQTGEHNYPKLELVRLTIPRRVYTDRHMDVVAYSVKHLWKERDTIRGLRMVYEPPTLRFFTARFEPIS
What are the official names of this protein?
Tyrosine phenol-lyase, Beta-tyrosinase.
What is the protein family that this protein belongs to?
Belongs to the beta-eliminating lyase family.
Protein: TRPD_PSESM
Sequence: MNIKSALNRVVNQLDLSTDEMRDVMREIMTGQCTEAQIGAFLMGMRMKSETIDEIVGAVSVMRELADKVELKTLDGVVDIVGTGGDGANIFNVSTASAFVISAAGCTVAKHGNRAVSGKSGSADLLEAAGVYLNLTPVQVARCIDSVGIGFMFAQSHHSAMKHTAGPRRELGLRTLFNMLGPLTNPAGVRHQVVGVFNQALCRPLAEVLLRLGSKHVLVVHSQDGLDEFSLAAPTFVAELKNGEVTEYWVQPEDLGIKSQSLYGLAVESPAQSLELIRDALGRRKTEIGQKAAEMIVLNAGAALYAADHATSLKEGVALAHDALHTGLAREKLDELGAFTAVFKQENEA
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: FCK4_FUSPC
Sequence: MTDSIHGGHPNIIRSCGASESMWTASHALGLYLRVSNIATLTIPTWKAKFKKSSASHFIRTAVVQVMLKQPAMRVGIIGENSKQPRFVALSSVDFSQQVEYAEAPSVDSVARSLEKLLLQPWPNLSKRPGWHVRVFHEPSSADKDVCRLRICLTVHHAIFDGESTARFHTSLIDALNNPDPAVARMMDKSPVVNLTGDCRDYPLTQEELINFTADIFWIASELWNILAPSFLKPFTFQTWAGEPYNPDIQAINIRYLSLNPIVTQAVVKRCREEKTTMTNLLNTLCATSLARRVPLTERQGFVNLTAVSLRPWIPENLHPNKTCMSVCASSHAQDFGPDVLAKIRQAEDATIWELAVKLRQDMKRRTDTMPHNEFSYLLRYAGDWRDIFQARYGKPRRELWTLSNLGSIATPASKGPWELESVLFAQFAPVVSCALAVNAASVEGGDMMVSLVWQDGILETDLVEGVRDDLEMWLLGLGNEGNLGISSSM
What is the function of this protein?
Probable alcohol acetyltransferase; part of the gene cluster that mediates the biosynthesis of cytokinins such as fusatin, fusatinic acids or 8-oxofusatin, known for their growth promoting and anti-senescence activities toward host plants (PubMed:28802024).  FCK1 is a bifunctional enzyme that performs the first steps in the biosynthesis of Fusarium cytokinins (PubMed:28802024).  It first condenses adenosine monophosphate (AMP) with dimethylallyl diphosphate (DMAPP) to yield isoprenyl adenosine monophosphate (PubMed:28802024).  It then catalyzes the removal of the phosphoribose to produce isopentenylaldehyde (PubMed:28802024).  The cytochrome P450 monooxygenase then converts isopentenylaldehyde to trans-zeatin (PubMed:28802024).  A condensation step converts trans-zeatin to fusatin which is further modified to produce fusatinic acid (PubMed:28802024).  The mechanism for oxidation of fusatin to fusatinic acid remains unknown (PubMed:28802024).  8-oxofusatin could be produced through several pathways, via direct oxygenation of fusatin, or via the 8-oxo-pentenyladenine intermediate which itself must arise from either the prenylation of 8-oxo-AMP by FCK1 and/or oxygenation of isopentenylaldehyde (PubMed:28802024).  Both the FCK3 and FCK4 enzymes act downstream of the identified cytokinins to produce yet unidentified compounds (PubMed:28802024).
What are the official names of this protein?
Probable alcohol acetyltransferase FCK4, Cytokinin biosynthesis protein 4.
What is the protein family that this protein belongs to?
Belongs to the alcohol acetyltransferase FCK4 family.
Protein: EFP_CHLL2
Sequence: MTSISNVSKGSIIRFKGEPHIIESLVHRTPGNLRAFYQANMKNLKTGRNVEYRFSASESVDLIVTERKQYQYLYRDGNDYVMMDNDTFDQINVQELSIGPSARFLKDGINVTIIFSDDGSILDVELPTFVEVEVMETSPATKDDRATSGTKPATVETGAEVSVPMFIQCGSVIRVDTRTGEYIERVKK
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAS1_SCHPO
Sequence: MVEAEQVHQSLRSLVLSYAHFSPSILIPASQYLLAAQLRDEFLSLHPAPSAESVEKEGAELEFEHELHLLAGFLGLIAAKEEETPGQYTQLLRIITLEFERTFLAGNEVHAVVHSLGLNIPAQKDVVRFYYHSCALIGQTTKFHGSALLDESSVKLAAIFGGQGYEDYFDELIELYEVYAPFAAELIQVLSKHLFTLSQNEQASKVYSKGLNVLDWLAGERPERDYLVSAPVSLPLVGLTQLVHFSVTAQILGLNPGELASRFSAASGHSQGIVVAAAVSASTDSASFMENAKVALTTLFWIGVRSQQTFPTTTLPPSVVADSLASSEGNPTPMLAVRDLPIETLNKHIETTNTHLPEDRKVSLSLVNGPRSFVVSGPARSLYGLNLSLRKEKADGQNQSRIPHSKRKLRFINRFLSISVPFHSPYLAPVRSLLEKDLQGLQFSALKVPVYSTDDAGDLRFEQPSKLLLALAVMITEKVVHWEEACGFPDVTHIIDFGPGGISGVGSLTRANKDGQGVRVIVADSFESLDMGAKFEIFDRDAKSIEFAPNWVKLYSPKLVKNKLGRVYVDTRLSRMLGLPPLWVAGMTPTSVPWQFCSAIAKAGFTYELAGGGYFDPKMMREAIHKLSLNIPPGAGICVNVIYINPRTYAWQIPLIRDMVAEGYPIRGVTIAAGIPSLEVANELISTLGVQYLCLKPGSVEAVNAVISIAKANPTFPIVLQWTGGRAGGHHSFEDFHSPILLTYSAIRRCDNIVLIAGSGFGGADDTEPYLTGEWSAAFKLPPMPFDGILFGSRLMVAKEAHTSLAAKEAIVAAKGVDDSEWEKTYDGPTGGIVTVLSELGEPIHKLATRGIMFWKELDDTIFSLPRPKRLPALLAKKQYIIKRLNDDFQKVYFPAHIVEQVSPEKFKFEAVDSVEDMTYAELLYRAIDLMYVTKEKRWIDVTLRTFTGKLMRRIEERFTQDVGKTTLIENFEDLNDPYPVAARFLDAYPEASTQDLNTQDAQFFYSLCSNPFQKPVPFIPAIDDTFEFYFKKDSLWQSEDLAAVVGEDVGRVAILQGPMAAKHSTKVNEPAKELLDGINETHIQHFIKKFYAGDEKKIPIVEYFGGVPPVNVSHKSLESVSVTEEAGSKVYKLPEIGSNSALPSKKLWFELLAGPEYTWFRAIFTTQRVAKGWKLEHNPVRRIFAPRYGQRAVVKGKDNDTVVELYETQSGNYVLAARLSYDGETIVVSMFENRNALKKEVHLDFLFKYEPSAGYSPVSEILDGRNDRIKHFYWALWFGEEPYPENASITDTFTGPEVTVTGNMIEDFCRTVGNHNEAYTKRAIRKRMAPMDFAIVVGWQAITKAIFPKAIDGDLLRLVHLSNSFRMVGSHSLMEGDKVTTSASIIAILNNDSGKTVTVKGTVYRDGKEVIEVISRFLYRGTFTDFENTFEHTQETPMQLTLATPKDVAVLQSKSWFQLLDPSQDLSGSILTFRLNSYVRFKDQKVKSSVETKGIVLSELPSKAIIQVASVDFQSVDCHGNPVIEFLKRNGKPIEQPVEFENGGYSVIQVMDEGYSPVFVTPPTNSPYAEVSGDYNPIHVSPTFAAFVELPGTHGITHGMYTSAAARRFVETYAAQNVPERVKHYEVTFVNMVLPNTELITKLSHTGMINGRKIIKVEVLNQETSEPVLVGTAEVEQPVSAYVFTGQGSQEQGMGMDLYASSPVARKIWDSADKHFLTNYGFSIIDIVKHNPHSITIHFGGSKGKKIRDNYMAMAYEKLMEDGTSKVVPVFETITKDSTSFSFTHPSGLLSATQFTQPALTLMEKSAFEDMRSKGLVQNDCAFAGHSLGEYSALSAMGDVLSIEALVDLVFLRGLTMQNAVHRDELGRSDYGMVAANPSRVSASFTDAALRFIVDHIGQQTNLLLEIVNYNVENQQYVVSGNLLSLSTLGHVLNFLKVQKIDFEKLKETLTIEQLKEQLTDIVEACHAKTLEQQKKTGRIELERGYATIPLKIDVPFHSSFLRGGVRMFREYLVKKIFPHQINVAKLRGKYIPNLTAKPFEISKEYFQNVYDLTGSQRIKKILQNWDEYESS
What is the function of this protein?
Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH.  The beta subunit contains domains for: [acyl-carrier-protein] acetyltransferase and malonyltransferase, S-acyl fatty acid synthase thioesterase, enoyl-[acyl-carrier-protein] reductase, and 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase.
What are the official names of this protein?
Fatty acid synthase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the fungal fatty acid synthetase subunit beta family.
Protein: CYC_ARUMA
Sequence: ASFAEAPPGNPKAGEKIFKTKCAQCHTVEKGAGHKQGPNLNGLFGRQSGTTAGYSYSAANKNMAVIWEESTLYDYLLNPXKYIPGTKMVFPGLXKPQERADLIAYLKESTA
What is the function of this protein?
Electron carrier protein.  The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase.  Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
What are the official names of this protein?
Cytochrome c.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane.
Protein: EFTS_CHLPD
Sequence: MSQISAKDVKHLRDTTGVGMMDCKKALEETGGDMQKAVEYLRKKGAALAAKRADKDAREGIVCIALGDDHKAGAILELNCETDFVARGEMFTGFAQELVSLALAKHAESPEAVMGLELSEAYGCEKVEDAIKTMTGKLGEKIDLKRLMFFEAQDGIIEAYVHPGSQLGTMVQLVTDQPEKAKELAKDLAMQVAASAPLVTDRSKVPAEYIEKEIEIYRQQALGQGKQEKFIEKIVSGRIEKYYQEVVLTEQVFIKDNNTKVSDVLNEFRKAHQAQVDVKAFVRYQLGE
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNG_SUHVF
Sequence: MEGPPPSKRPCGLPPGVRLVVPAAAASASNAATAAAAAAPAGAGAGASKPARPPAAARPAKGTPAASAATTATGADASAPAPDPGAPTWDAFAAEFDVAPSWRALLEPEIAKPYARLLLAEYRGRCLTEEVLPAREDVFAWTRLTAPEDVKVVIIGQDPYHGPGQAHGLAFSVRRGVPIPPSLANIFAAVRATYPTLPAPAHGCLEAWARRGVLLLNTTLTVRRGVPGSHAPLGWARLVRAVVQRLCETRPKLVFMLWGAHAQKACAPDPRRHKVLTFSHPSPLARTPFRTCPHFGEANAYLVQTGRAPVDWSVD
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or deamination of cytosines.  Therefore may reduce deleterious uracil incorporation into the viral genome, particularly in terminally differentiated cells which lack DNA repair enzymes.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG, UNG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: COX2_ARVSO
Sequence: MAYPFQLGLQDATSPIMEELTNFHDHTLMIVFLISSLVLYIISLMLTTKLTHTSTMDAQEVETIWTILPAAILILIALPSLRILYMMDEINNPVLTVKTMGHQWYWSYEYTDYEDLCFDSYMIPTNDLKPGELRLLEVDNRVVLPMELPIRMLISSEDVLHSWTVPSLGLKTDAIPGRLNQATLSSNRPGLYYGQCSEICGSNHSFMPIVLEMVPLKYFENWSTSMI
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TSGA_YERPA
Sequence: MNNSNRIRLTWISYLSYALTGALVIVTGIVMGNIAEYFNLPIASMSNTFTFLNAGILISIFLNAWLMEIIPLKRQLVFGFILMLIAIAGLMVGHNLMIFSISMFIFGVVSGITMSIGTFLVTHMYEGRQRGSRLLFTDSFFSMAGMIFPIAAAMLLARHIEWYWVYACIGLLYVGIFVLTLCSEFPVLGHKATDQSKPVVKEKWGVGVLFLAIAALCYILGQLGFIQWVPEYATKTFNMNISQAGQLVSNFWISYMIGMWIFSFILRFFDLQRIVTVLAAMATLAMYLFVSTDNPAYLSYYILALGFVSSAIYTTLITLGSLQTKVSSPKLVNFILTCGTVGTMLTFVVTGPIVANNGVHAALETANGLYLAVFILCLALGFFTKHRSHGHVTH
What are the official names of this protein?
Protein TsgA homolog.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TsgA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYF_SYNPW
Sequence: MRRLLSPLFAALIVGVTVLTAPSTSWAYPFWAQQNYDSPREATGKIVCANCHLAQKLTQAEVPQSVLPDSVFKAVVKIPYDTSVPEIGADGSEVPLQVGAVVMLPDGFTLAPQDRWTDDIKEETEGVYFSEYSDDQPNVILVGPIPGDQHQEIVFPVLSPDPATDSNIHFGKYSIHVGGNRGRGQVYPTGEKSNNTVFTAPSTGTVRSIEAGENGASVVTIASADGTELSETVPVGPALIVSVGDAVEAGAPITNDPNVGGFGQLDTEVVLQNPVRIYGLLAFFAAVALAQIMLVLKKKQFEKVQAAEGV
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome f family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: PYRD_ECOSE
Sequence: MYYPFVRKALFQLDPERAHEFTFQQLRRITGTPFEALVRQKVPAKPVNCMGLTFKNPLGLAAGLDKDGECIDALGAMGFGSIEIGTVTPRPQPGNDKPRLFRLVDAEGLINRMGFNNLGVDNLVENVKKAHYDGVLGINIGKNKDTPVEQGKDDYLICMEKIYAYAGYIAINISSPNTPGLRTLQYGEALDDLLTAIKNKQNDLQAMHHKYVPIAVKIAPDLSEEELIQVADSLVRHNIDGVIATNTTLDRSLVQGMKNCDQTGGLSGRPLQLKSTEIIRRLSLELNGRLPIIGVGGIDSVIAAREKIAAGASLVQIYSGFIFKGPPLIKEIVTHI
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MDM34_ASHGO
Sequence: MSFIFNRETFEDNSFNEVLREKLMRALNLHDRTVGSSSGAMTTGTGAVECSGAAAAGQRPPRSKGGFSKVDILKSGIIVKKVEFPTIPKLEILDLDVSIQSKSLIKGICKVSCRDAMVQITTEIESNLLLLHVNSSPKFTTPKLISNDSFTVPITMTFDKLHLEAITNIFVKNTGVGISFNDVNLDFRLQCSIKLLQSSIEKRLKASMEEVFKDVLPSVIFNMSQRWFTHGETVVPTVDKSMVSSDTPVQPRMILDESDLSDLSPANMLRLSTLVSSRQTLCLNPTAVDTISTIPGCLERQNLHRFNLRFPSLYNYYSNKEQQGAHNNEKNRVEHLKLWGRSSSNPIPTRASFKVENTLPKEVLDSNSYDVRVITAIQTKMYERASNDVVLRRRKIKMRSRKPSKANKDAVSPAQNDSGTSSCSNVASELPHASLQANPQSDEIDPAPEGGPNAEDAYKEELEDSGLRAPQDFPALENVTPVLAQLPNQQRSRLGSPLSAGRPTPLLSPLDDSHWLLQKRDPQDLRTTLYSPIRNGRFYVMPQPQLDTKEASAFLLENGKRFGFVGLLNNHNLKWGNDPPPPYREVSITQ
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 34.
What is the protein family that this protein belongs to?
Belongs to the MDM34 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria- endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: LOLB_XANC8
Sequence: MSQVIRTLALTGLALAGLSGCVSVPRGQGGAAPAVVGQVSESAQQAETARQAWLQAHPAWSFQGRVAISKGRDGGSGRLDWQQDGPRYHVQLSAPVTRQSWVLTGDTTTGAGRLEGLDGGPRAGADAEQVLLEATGWTIPVNQMPDWVRALRIADAGAARVDLDEHGRPRTVQQDGWTIDFLEWTPASAAQPELPRRIEARNGDAKVRLLVDQWTLSP
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: MDTA_ERWAE
Sequence: MKTPRRFPLIALTVAAVLTAAALYWWYSHSTASTVQNRQGTEQQRASNSQGSAKRAGNAPPVQAAEALRQNVPQYLSGLGTVTAANTVTLRSRVDGDLVALHFNEGQEVAAGQLLAEIDPRPYEVALMQAEGQLAKDRATLTNARRDLARYEKLAQTQLVSAQELDTQRARVSETLGTIKADEGSVASARLNLTYSRVTAPIAGRVGLKQVDVGNYVSSGDANGIVVIAQTHPIDLVFSLPESDIASVLSAQKNGKLPVEAWDRNNKNLLTRGTLLSMDNQIDSTTGTVKLKARFDNQDDRLFPNQFVNARLKIGTLEDAIVIPAAALQMGNESHFVWVINGDSTVSKKIVASGLQGSGQVVISAGLQAGEKVVTDGIDRLTDGAQTEIVPAQASTPLPASGASS
What are the official names of this protein?
Multidrug resistance protein MdtA, Multidrug transporter MdtA.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NUOD_BRASB
Sequence: MNEQSPALRNFTINFGPQHPAAHGVLRLVLELDGEVVERVDPHIGLLHRGTEKLIETKTYLQAMPYFDRLDYVAPMNQEHAFCLAAERLLGIEVPRRGQLIRVLYSEIGRLLSHLLNVTTQAMDVGALTPPLWGFEEREKLMVFYERASGSRMHANYFRIGGVHQDLPPKLIDDIDAFCDPFLKVVDDLDQLLTGNRIFKQRNVDIGVVTLKQAWEWGFSGVMVRGSGAAWDLRKSQPYDVYAEMEFDVPIGKNGDCYDRYLIRMEEMRQSVRIMKQCIQKLRAPDGQGPVVVTDNKIAPPRRGEMKRSMEALIHHFKLYTEGVHVPAGEIYAAVEAPKGEFGVYLVSDGSNKPYKCKIRAPGFAHLQAMDFLCRGHLLADVSAILGSLDIVFGEVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: IDI2_STAHJ
Sequence: MSDFQREQRKNEHVEIAMAQSDAPQSDFDRVRFVHHSIPSINVDEVDLTSRTTDFDMTYPIYINAMTGGSEWTKQINEKLAVVARETGLAMAVGSTHAALRNPKMAESFSIARQTNPEGIIFSNVGADVPVDKAVEAVSLLDAQALQIHVNAPQELVMPEGNREFSTWLDNVAAIVQRVDVPVIIKEVGFGMSKELYKDLIDVGVTYVDVSGKGGTNFVTIENERRSNKDMDYLANWGQSTVESLLESSAYQDSLNVFASGGVRTPLDVVKSLALGAKAVGMSRPFLNQVENGGITTTIEYVESFIEHTKSIMTMLNARDISELKQSKFVFDHKLMSWIEQRGLDIHRG
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPH_SALNS
Sequence: MRPAGRSANQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTASIEEGVPRFLKGQGQGWITAEYGMLPRATHTRNAREAAKGKQGGRTMEIQRLIARALRAAVDLKTLGEFTITLDCDVIQADGGTRTASITGACVALADALNKLVANGKLKTNPMKGMVAAVSVGIVNGEAICDLEYVEDSAAETDMNVVMTEDGRIIEVQGTAEGEPFSHEELLTLLALARGGIESIVATQKAALEN
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: PYC_BACSU
Sequence: MSQQSIQKVLVANRGEIAIRIFRACTELNIRTVAVYSKEDSGSYHRYKADEAYLVGEGKKPIDAYLDIEGIIDIAKRNKVDAIHPGYGFLSENIHFARRCEEEGIVFIGPKSEHLDMFGDKVKAREQAEKAGIPVIPGSDGPAETLEAVEQFGQANGYPIIIKASLGGGGRGMRIVRSESEVKEAYERAKSEAKAAFGNDEVYVEKLIENPKHIEVQVIGDKQGNVVHLFERDCSVQRRHQKVIEVAPSVSLSPELRDQICEAAVALAKNVNYINAGTVEFLVANNEFYFIEVNPRVQVEHTITEMITGVDIVQTQILVAQGHSLHSKKVNIPEQKDIFTIGYAIQSRVTTEDPQNDFMPDTGKIMAYRSGGGFGVRLDTGNSFQGAVITPYYDSLLVKLSTWALTFEQAAAKMVRNLQEFRIRGIKTNIPFLENVAKHEKFLTGQYDTSFIDTTPELFNFPKQKDRGTKMLTYIGNVTVNGFPGIGKKEKPAFDKPLGVKVDVDQQPARGTKQILDEKGAEGLANWVKEQKSVLLTDTTFRDAHQSLLATRIRSHDLKKIANPTAALWPELFSMEMWGGATFDVAYRFLKEDPWKRLEDLRKEVPNTLFQMLLRSSNAVGYTNYPDNVIKEFVKQSAQSGIDVFRIFDSLNWVKGMTLAIDAVRDTGKVAEAAICYTGDILDKNRTKYDLAYYTSMAKELEAAGAHILGIKDMAGLLKPQAAYELVSALKETIDIPVHLHTHDTSGNGIYMYAKAVEAGVDIIDVAVSSMAGLTSQPSASGFYHAMEGNDRRPEMNVQGVELLSQYWESVRKYYSEFESGMKSPHTEIYEHEMPGGQYSNLQQQAKGVGLGDRWNEVKEMYRRVNDMFGDIVKVTPSSKVVGDMALYMVQNNLTEKDVYEKGESLDFPDSVVELFKGNIGQPHGGFPEKLQKLILKGQEPITVRPGELLEPVSFEAIKQEFKEQHNLEISDQDAVAYALYPKVFTDYVKTTESYGDISVLDTPTFFYGMTLGEEIEVEIERGKTLIVKLISIGEPQPDATRVVYFELNGQPREVVIKDESIKSSVQERLKADRTNPSHIAASMPGTVIKVLAEAGTKVNKGDHLMINEAMKMETTVQAPFSGTIKQVHVKNGEPIQTGDLLLEIEKA
What is the function of this protein?
Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production (PubMed:4146915).  Fulfills an anaplerotic function in B. subtilis as it is necessary for growth on glucose, but is not required for sporulation (PubMed:4146915).
What are the official names of this protein?
Pyruvate carboxylase, Pyruvic carboxylase, PYC.