PharMolix/UniProtQA huggingface dataset:
Protein: GUF1_PLAKH
Sequence: MIDAWAIKRALCIFILINCVLKLGRSRKITWKPKKGVYIPLDDANGCKGEWKRKGVFFNIQSGKKGKRLKGRKGLRRGLVTRGTPQFRRDKFIPLFLLQDCEHRSLNGKQYNLRGRRCSSPLDVNPRGWDILPPEQPNEETIGERIGERIGEAEQLEDEGLDGGPPPGMEAKKSSSSSSSNNVHSNCSDAGKAPVCSQENIRNFCILAHIDSGKSTLADRFLELTKTIKKKKMQDQFLDMMSLEREKGITIKLKAVRMNYKNYIFNLIDTPGHFDFYHEVKRSLSVCEGAILLIDGTKGIQSQTLNIFMELQKHNLKIIPVINKIDLNICRLEKIENDLLNKFHFMKKDILHISAKYSHGVESLFQRIVSEIPSPAIKSNSFFRAIVFDSFYDQYKGVILIIKVLNGVLTKKTEVFFIQSEKTYIIQEVGYLTPEMKPTESIRQGDIAYVSSNIRKCDEVQMSETIISRDIVHLNAQRRLVVDSDLLRRNPSGEEHINVKRCNIDSSLGGVAPRMERIEREVNLEEIAASKVDVSYPVVFCNIYSVNDKQANELQAALNKLKLNDASFSFKPDVCETLGKGFKCGFNGLLHLNIIQERIKREYDVETIVTAPSVNYLIRVKEKCIDKQLKERLIDASFDIANINVEGGDHDDCNDNGGSNSDDRSDRSGKNPPDGLYYMTSNVNDIPQKNYIHGIYEPYVRTSIMTPEEYQKYIMAECFQRRGIFIKKESMDSHIIFYFDMPLSEILINFLDQIKSCTKGYGSMSYENFITYRESDLHKINIYVNNRSIDSLSFLAHKLNYQEKGKRIVLKLKEMIKPHQFLVVIQAGIGTRIFASERINPLRKNVTAKCYGGDITRRRKLLEKQSAGKKKMFSIGKVKLPPNMFTKLFDLKAQ
What is the function of this protein?
Promotes mitochondrial protein synthesis.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Binds to mitochondrial ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Translation factor GUF1 homolog, mitochondrial, Elongation factor 4 homolog, EF-4, GTPase GUF1 homolog, Ribosomal back-translocase.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: SLMH_RHIRD
Sequence: MLPADQAGIPPCQGPRARSAPISFAIPKGAWDTHLHVFGPTAVFPYAEKRPYTPPDSPLEDYLALMERLGIERGVCVHPNVHGIDNSVTIDAVERSDRRLLGIIKPHRVMTFTELRDLKTRGVRGVRFAFNPQHGSGALDTELFERMHGWCRELDWCINMHFAPDALEGLCDLIAGAETPIIIDHFGRVETAAGVNQLPFKILRDLATLDHVWIKLTGADRISHSGVPYDDVVPFAHALSEIAPDRLLWGSDWPHSGYFDPKRMPDDGDLLNLVARFAPDVALRHKILVDNPARLFGVI
What is the function of this protein?
Involved in the degradation of 4-sulfocatechol which is a central intermediate in the degradation of substituted sulfonated benzenes.  Catalyzes the hydrolytical desulfonation of 4-sulfomuconolactone to yield maleylacetate.
What are the official names of this protein?
4-sulfomuconolactone hydrolase, 4-carboxymethylen-4-sulfo-but-2-en-olide hydrolases.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Sulfomuconolactone hydrolase family.
Protein: ACDH2_NOCSJ
Sequence: MTASTIPRQIAIIGSGNIGTDLMIKVLRLSKTLEVGAMVGIDPDSDGLARANRLGVPTTSDGVDGLIRMPNFEAIDIVLDATSARAHAANYTALRRYRKRMIDLTPAAVGPFVVPAVNMGASLSADNVNMVTCGGQATIPIVAAISQVTPVAYAEIVASIASKSAGPGTRQNIDEFTETTAHAIEQVGGARKGKAIIILNPAEPPLIMRDTVLALIGPSDHDAVKGSIRAMVDAVAEYVPGYRLKQRIEIQPLDGLPVGTLTSEPVTHKVSVFLEVEGAAHYLPAYAGNLDIMTSAALRVAEAMAAQKLSGAVA
What are the official names of this protein?
Acetaldehyde dehydrogenase 2, Acetaldehyde dehydrogenase [acetylating] 2.
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: CAPS1_SIFVH
Sequence: MAGRQSHKKIDVRNDTSTRYKGKLYGIFVNYMGEKYAQQLVENMYSNYNDVFVEIYNKMHNALRPTLVKLAGAGATFPLWQLVNEAIYAVYLTHKETASFLVTKYVARGVPAMTVKTLLAEVGNQLKELVPAVAEQIGSVTLDHTNVVSTVDNIVTSMPALPNSYAGVLMKTKVPTVTPHYAGTGTFSSMESAYKALEDIERGL
What is the function of this protein?
Self-assembles to form a helical, filamentous nucleocapsid mesuring 1980 nm in length and 24 nm in width.  Together with capsid protein 2, wraps arounds the DNA and maintains it in an A-form.  Capsid proteins probably maintain the DNA in A-form by non-specific desolvation and specific coordination of the DNA phosphate groups by positively charged residues.  This certainly protects the viral DNA under conditions such as the extreme desiccation of its host.
What are the official names of this protein?
Major capsid protein 1, MCP1.
What are the subcellular locations of this protein?
Virion.
Protein: RPOZ_HELP2
Sequence: MKKERTESLVAQALKNIGNDRYKLDNLVFARVKQLNAGAKTLVNMDPKRHKLVDIAIREIAEGKIDIDRIDERN
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: NUON_SULDN
Sequence: MLSPVNVSIESLNLMTLVPMLIPIIGALFIIVIDLFKSEQDKSLYVMLSLLILGVDFVALVDSAGVFANNGTIMGVFDMMLIDGLAILSQFIIVGASMLFIPLALTHKRFHEFSYPEFFALFLFMIAGFQFMVSTDNLILIFVGLETASLALYTLIAMHNRDKSFEAAVKYFTMGALAAGFFSFGSMVFYALTGSVEINQIATVLTANNYADIGFVLVGVVFLLAAFGFKLSMVPFHTWTPDVYEGSSAALAGYMSIVPKIAAFIVAMRLFEFLIHSGVVWLEVILYMGVVVTMTMANIWALVQSDVKRMLAYSSISHAGFVMAAILIGTTQSNSALFLYWILFSFTNLGSFSMLWISRQKNLPAHQQSDHSYDKFAGMVKTSPVAASIMALFMLSLAGIPPFALFWGKMYLMSSAITGGYTVLALIMALNSAIAGYYYLKLIVYMFMKDPVVENNGHVYSANATLPLKTIIGIAAIGTIFAFVAVNQLIEFVTLFVYNSGY
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CNTA_STAAM
Sequence: MRKLTKMSAMLLASGLILTGCGGNKGLEEKKENKQLTYTTVKDIGDMNPHVYGGSMSAESMIYEPLVRNTKDGIKPLLAKKWDVSEDGKTYTFHLRDDVKFHDGTTFDADAVKKNIDAVQQNKKLHSWLKISTLIDNVKVKDKYTVELNLKEAYQPALAELAMPRPYVFVSPKDFKNGTTKDGVKKFDGTGPFKLGEHKKDESADFNKNDQYWGEKSKLNKVQAKVMPAGETAFLSMKKGETNFAFTDDRGTDSLDKDSLKQLKDTGDYQVKRSQPMNTKMLVVNSGKKDNAVSDKTVRQAIGHMVNRDKIAKEILDGQEKPATQLFAKNVTDINFDMPTRKYDLKKAESLLDEAGWKKGKDSDVRQKDGKNLEMAMYYDKGSSSQKEQAEYLQAEFKKMGIKLNINGETSDKIAERRTSGDYDLMFNQTWGLLYDPQSTIAAFKAKNGYESATSGIENKDKIYNSIDDAFKIQNGKERSDAYKNILKQIDDEGIFIPISHGSMTVVAPKDLEKVSFTQSQYELPFNEMQYK
What is the function of this protein?
Part of the ABC transporter complex CntABCDF (Opp1) involved in the uptake of metal in complex with the metallophore staphylopine (StP).  May be involved in the import of a large array of divalent metals ions such as nickel, cobalt, zinc, copper and iron.  Binds the metal via the metallophore StP, and transfers the StP-metal complex to the membrane-bound permease.
What are the official names of this protein?
Metal-staphylopine-binding protein CntA.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 5 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: FPG_SYNP6
Sequence: MPELPEVETVRRGLTQQTLQRVCTGGEVLLSRTIATPTPELFLVALQQTQIQEWRRRGKYLLADLSREGEPAGTWGVHLRMTGQFFWTEPATPLTKHTRVRLRFEGDRELRFIDIRSFGQMWWVPPDRPVESVITGLSKLGPEPFAPEFTARYLRDRLRRSQRPIKTALLDQSLVAGIGNIYADESLFRTGIHPTTPSDRLTKIQAEKLREAIVEVLTASIGAGGTTFSDFRDLTGVNGNYGGQAWVYGRKDQPCRTCGTPIQKLKLAGRSSHFCPRCQPCS
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity).
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: TCAL8_BOVIN
Sequence: MQKSCGENERKPQNMPKAEEDRPLEAVPQEAEGNPQPSEEGVSQEAEGNLRGGLTQPGQGYKEDSPVRHLDPEEMIRGADELERLREEIRRVRNKFVMMHWKQRHSRSRPYPVCFRP
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Transcription elongation factor A protein-like 8, TCEA-like protein 8, Transcription elongation factor S-II protein-like 8.
What is the protein family that this protein belongs to?
Belongs to the TFS-II family. TFA subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: THIC_NATPD
Sequence: MTTQLQHARGGTVTDAMERVAERENRDAEFVRQQVADGQAVIPANHGHDALDPMIIGREFATKVNANIGNSEPASGPEAELQKLHTAVHYGADTVMDLSTGGDLDTIRTENIAYSPVPVGTVPIYEAVTRVDDASDLTPELLLDVVEKQAEQGVDYMTLHAGVLAEHLPLTDGRTTGIVSRGGSILARWMEEHGEQNPLYERFDDLCEILAAYDVTVSLGDGLRPGSLADASDAAQFAELDTLGELTRRAWDHGVQVMVEGPGHVPMDEIADNVERQQDVCDGAPFYVLGPLVTDVAPGYDHITSAIGATEAARAGAAMLCYVTPKEHLGLPDAEDVRDGLAAYRIAAHSADVANGRPGARDWDDAVSEARYAFDWRRQFELALDPGRARNYHDQTLPEDNYKEARFCSMCGVEFCSMRIDQDAREAGDGMDGLESRTDLDSSAAAAVNRPPTGVHRAEKLDDIPCPVAEDDVAADD
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: RS18_BACCR
Sequence: MAGRKGGRAKRRKVCFFTANGITRIDYKDVDLLKRFVSERGKILPRRVTGTSAKYQRKLTVAIKRARQMALLPYVGE
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: NADC_MYCLE
Sequence: MLSDCEFDAARDTIRRALHEDLRYGLDITTQATVPAGTVVTGSMVPREPGVIAGVDVALLVLDEVFGVDGYRVLYRVEDGARLQSGQPLLTVQAAARGLLTAERTMLNLVCHMSGIATVTVAWVDAVRGTKAKIRDTRKTLPGLRALQKYAVRVGGGVNHRLGLGDTALIKDNHVAAVGSVVDALRAVRAAAPELPCEVEVDSLEQLDAMLAEEPELILLDNFPVWQTQVAVQRRDIRAPTVLLESSGGLSLENAAIYAGTGVDYLAVGALTHSVRILDIGLDL
What is the function of this protein?
Involved in the catabolism of quinolinic acid (QA).
What are the official names of this protein?
Nicotinate-nucleotide pyrophosphorylase [carboxylating], Quinolinate phosphoribosyltransferase [decarboxylating], QAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NadC/ModD family.
Protein: HSR9_CAEEL
Sequence: MASSSNTMEFEEDDSTVTQTSLPTTTSVLDKSRSLFGNSAVISTPARDSTPDGHIVDSSVITKSSVIIEAEDEPDVAADVTALDKEKAEDEPQCSAGKDAKSGESMNDSEKSESPIEEGEGETFEKKIISMDTSDDKLDIAESISVSNDTEKPEENEEKVVGDEDEEDIDDVQEDDEDEAPKKKTKKAVSTSDDDDLHEDDSPKGGSVSDEKEEPENEDDTEEPENEVEVESPVKEQADSGEPIENVNDDKASEPGVGEISQDSVDDSQKIGLDSKSPDGESEANEENQESQSSSRSTRRAKRVSATVSSTPSSNTPRRGGRGQKSEVNADETKTPIVSNSTPRRGRSSRGGDRDEVIDPTENVVGDSGVEETSPRKGRSRRSVATEDTSVTEEVENTEHPTEEETPKQGRGRRSAASSSATSSAVPTPRSTRGRGRKSQANEENLQEKETEDPTKTHDTNQAKSTRTPRGRRSNADAETMESVEAEKVETPTSSRRSTRAKPPAKSAPVTPAVTNKRTTVRGRKKQGSITEDPIEEADETIEETLPQKKGRGAAKSAPSSSKKSAEYDPYDLDTEMEHHPEPLKNIHMEVHNFGAVKYAKLGNSESKYSMTEKAAESRIAELQSSPAAKNRRSLADMTPGKDKMKHRVSSVGTSGRRSRAKKEEEHHENDIEMEDAPATATPASSNRGRKRKSEASDIKTPPAKKEPVIPLKNLSDEDQLLVDHPQDDNEPHAPGARVYAVFQKMFYPAVVLSERDGLGRYKVQFTVDNVIKDVPNSGIIPLRALSPGKTAVYNESDVRLDSGPNDISAAEWKKGKLTISIMDEDGEPTDEVKVVDWYDVSFDHSEWRDYVKSKDQSATAIVTSNITTISEATRARKPTTVSNQAKPKGRKKKGVDLVSSRGGSASPAEEEEKLLPMNEEAIGKNIFTGKVFMLTSANRSNSASVPSMFKKKNLMNFITQNGGIVTEQLNSFQERYSNYEPLLISDTYYRTHKYLAALARGVPCVNNTWLQACGEQGKCVDYTDYVLPAGASIFDESQDMPAPKNPSELLKGTTIYVHSTHSAREVTQTGPGGTFIEIWKPILELLGADVVDGDWETLDETGLKFDVVLVDGTFRDEVMEYADTIGASRVTSEWVIQTIILGKAPEPNAHPKFDPYRLHHRTRH
What is the function of this protein?
May have a role in DNA double-strand break repair following gamma-irradiation.
What are the official names of this protein?
Protein hsr-9, Heat shock related protein 9, Tumor suppressor p53-binding protein 1 homolog, 53BP1.
What are the subcellular locations of this protein?
Nucleus. Note=Localized to the nuclei of proliferating germ cells.
Protein: RMD5B_MOUSE
Sequence: MEQCACVERELDKVLHKFLTYGQHCEQSLEELLHSVGQLRAELASAALQGTPLSATLSLVMSQCCRKIRDTVQKLASDHKDIHSSVSRVGKAIDRNFDSEICGVVSDAVWDSREKQQQILQMAIVEHLYQQGMLSVAEELCQESTLNVDLDFKQPFLELNRILEALHEQDLGPALEWAVSHRQRLLELNSSLEFKLHRLHFIRLLAGGPEKQLEALSYARHFQPFARLHQREIQVMMGSLVYLRLGLEKSPYCHLLDNSHWAEICETFTRDACSLLGLSVESPLSVSFASGCVALPVLMNIKAVIEQRQCTGVWSHKDELPIEIELGMKCWYHSVFACPILRQQTSDSNPPIKLICGHVISRDALNKLINGGKLKCPYCPMEQNPADGKRIIF
What is the function of this protein?
Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1.  MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex.  Catalytic activity of the complex is required for normal cell proliferation.  The CTLH E3 ubiquitin-protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1.
What are the official names of this protein?
E3 ubiquitin-protein transferase RMND5B, Protein RMD5 homolog B.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: NRX3_ARATH
Sequence: MAVSADYQVKFPESGDLYSILAAEGIEFLLSHSGEVPLEYIHGKTICLFFSAIWCRPCKDFTPELIKLYENLQNRGEELEIIFVSFDHDMTSFYEHFWCMPWLAVPFNLSLLNKLRDKYGISRIPSLVPLYSDEISVAEDVIGLIEDYGSEAFPFTKKRKEELKAIDDSKRLGGQLEKLLTHESRNYVVARNGSKVLVSKLVGKTIGLYFGAHWCPPFRSFTSQLVDVYNELATTDKGSFEVILISTDRDSREFNINMTNMPWLAIPYEDRTRQDLCRIFNVKLIPALVIIGPEEKTVTTNAREMVSLYGSRSFPFTESRIVELKACLKKEGDSLPRKVKDNKHEHELKLDMAKAYVCDFCKKQGRFWAFSCNACDYDLHPTCVEEEEALLV
What is the function of this protein?
Probable thiol-disulfide oxidoreductase that may participate in various redox reactions.
What are the official names of this protein?
Probable nucleoredoxin 3, AtNrx3.
What is the protein family that this protein belongs to?
Belongs to the nucleoredoxin family.
Protein: ZN350_HUMAN
Sequence: MIQAQESITLEDVAVDFTWEEWQLLGAAQKDLYRDVMLENYSNLVAVGYQASKPDALFKLEQGEQLWTIEDGIHSGACSDIWKVDHVLERLQSESLVNRRKPCHEHDAFENIVHCSKSQFLLGQNHDIFDLRGKSLKSNLTLVNQSKGYEIKNSVEFTGNGDSFLHANHERLHTAIKFPASQKLISTKSQFISPKHQKTRKLEKHHVCSECGKAFIKKSWLTDHQVMHTGEKPHRCSLCEKAFSRKFMLTEHQRTHTGEKPYECPECGKAFLKKSRLNIHQKTHTGEKPYICSECGKGFIQKGNLIVHQRIHTGEKPYICNECGKGFIQKTCLIAHQRFHTGKTPFVCSECGKSCSQKSGLIKHQRIHTGEKPFECSECGKAFSTKQKLIVHQRTHTGERPYGCNECGKAFAYMSCLVKHKRIHTREKQEAAKVENPPAERHSSLHTSDVMQEKNSANGATTQVPSVAPQTSLNISGLLANRNVVLVGQPVVRCAASGDNRGFAQDRNLVNAVNVVVPSVINYVLFYVTENP
What is the function of this protein?
Transcriptional repressor.  Binds to a specific sequence, 5'-GGGxxxCAGxxxTTT-3', within GADD45 intron 3.
What are the official names of this protein?
Zinc finger protein 350, KRAB zinc finger protein ZFQR, Zinc finger and BRCA1-interacting protein with a KRAB domain 1, Zinc finger protein ZBRK1.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Nucleus matrix. Note=Associated with the nuclear matrix.
Protein: TAP46_NICBE
Sequence: MGELSMQEMPLPALFEQGSKIHASAESSVDQDTVRKGCEILRQCEEMIGKLGLFSVNETKEDISTANLKYILVPYYLAELTEKVADNDRIKVLKASQAKLKEFISFCETMELVPEEEIETSTQGGANSSVDRRAKKIARFKRQRAAESKLLEIKERKERRGRSTKAAALSSPVETEEDDVLDDDGEEEREAWLTTISLGLCKAFDLLEMLKKEEEILSAVKEKQLQNGEKEFSQAILDERTKKVETWHRDAAARAHYTKPAAPITCATFAQDVIEGRAKVSQAHEHKHQPLIFGPASLVGRNPTTEREKIAAQVFQPHYRLPTMSIEEAGLTEMNMMNEWQERNVKLMEEANSSWYKDAPKSRPGEDDEEDDDDAAQDKARAWDDWKDDNPRGAGNKKLTPCG
What is the function of this protein?
Involved in the regulation of the TOR signaling pathway.  Seems to act as a regulator of PP2A catalytic activity.
What are the official names of this protein?
PP2A regulatory subunit TAP46, NbTAP46.
What is the protein family that this protein belongs to?
Belongs to the IGBP1/TAP42 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RS5_BACTN
Sequence: MAGVNNRVKVTNDIELKDRLVAINRVTKVTKGGRTFSFSAIVVVGNEEGIIGWGLGKAGEVTAAIAKGVESAKKNLVKVPVLKGTVPHEQSAKFGGAEVFIKPASHGTGVVAGGAMRAVLESVGITDVLAKSKGSSNPHNLVKATIEALSEMRDARMIAQNRGISVEKVFRG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: FLHD_BURL3
Sequence: MWELNMSYLWLAQRLLQSDRASGMFRLGVTADVAAALAALSMKQMNDLASAGQLICALRPSRYGVLSALTRATPPVDLVRVHTAMALAGLALPDEETS
What is the function of this protein?
Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region.  Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes.  Also regulates genes whose products function in a variety of physiological pathways.
What are the official names of this protein?
Flagellar transcriptional regulator FlhD.
What is the protein family that this protein belongs to?
Belongs to the FlhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_SYNC1
Sequence: MLETTIRNKLAQKDILLMTHIVIGYPDLDTSFEVVRTMVEAGVDLMELQIPFSEPMADGPVILKANQDALATGITVDECFDFAEKVAAAYDIPFLFMTYYNILFKYGVEAFAERMAKCGLCGAIVPDLPPEEADDYLAAMNKHGMAPIFIYAPNTTEARMQRIAEHGKGFIYCMARKGVTGLQTDFSGQLGDHLDHCRASTQLPLALGFGVKDRADVEFIKGKADIAVVGSQAIRVLDEGGVPAVEAFIRSLR
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: BEAN1_HUMAN
Sequence: MSFKRPCPLARYNRTSYFYPTFSESSEHSHLLVSPVLVASAVIGVVIILSCITIIVGSIRRDRQARLQRHRHRHHRHHHHHHHHRRRRHREYEHGYVSDEHTYSRSSRRMRYACSSSEDWPPPLDISSDGDVDATVLRELYPDSPPGYEECVGPGATQLYVPTDAPPPYSLTDSCPTLDGTSDSGSGHSPGRHQQEQRTPAQGGLHTVSMDTLPPYEAVCGAGPPSGLLPLPGPDPGPRGSQGSPTPTRAPASGPERIV
What are the official names of this protein?
Protein BEAN1, Brain-expressed protein associating with Nedd4 homolog, BEAN.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MEP5_COCP7
Sequence: MRVSSSLIALAALAVQALALPVNELAERDTGLDVKLIPIGNTRVKAIITNNADHEMSFVKYNTLFDSSPVRKVQISKDGSIVPFNGMRLYYDINNLPKEAYKTLAPGASAEAEFDIAETSDLSAGGSFEISAEGSIPVIDGQGTKPTGSIRFKANVLTMDIDGEMASKVASAIPELDKRTRVDGQTCTGQYAQLLQGGLRNCVTYAQRAAQAASGGNAQKFQEYFKTTSQQARQSVARRFQAIAQECSSANQGRTIYFCQDIYRNCQRGLIAYTIPARSHVVNCPDYWRLPPVVNRGLDPDHGYVVVHEFTHATSIFSPGTVDHAYGYEQCRRLNAQQSLSNADNYSLFAADVTRN
What is the function of this protein?
Secreted metalloproteinase that allows assimilation of proteinaceous substrates.  Shows high activities on basic nuclear substrates such as histone and protamine.  May be involved in virulence (By similarity).
What are the official names of this protein?
Neutral protease 2 homolog MEP5, Deuterolysin MEP5, Metalloproteinase 5.
What is the protein family that this protein belongs to?
Belongs to the peptidase M35 family.
What are the subcellular locations of this protein?
Secreted.
Protein: MNME_HAEI8
Sequence: MKETIVAQATAPGRGGIGILRVSGPLATKVAQAILGKCPKPRMADYLPFKDADGTILDQGIALYFKSPNSFTGEDVLELQGHGGQVVLDLLLKRILQIDGIRLARPGEFSEQAFLNDKLDLAQAEAIADLIDATSEQAARSALKSLQGEFSKKVNELVDSVIYLRTYVEASIDFPDEEIDFLADGKIEANLRGIINQLENVRSEAKQGSILREGMKVVIAGRPNAGKSSLLNALAGREAAIVTDIAGTTRDVLREHIHIDGMPLHIIDTAGLRDATDEVERIGISRAWTEIEQADRIILMLDSSDPESADLSKVRSEFLAKLPSTLPVTIVRNKIDLNGEQASESEQGGYQIISLSAQTHDGVKLLRDHLKQAMGFQTGIEGGFLARRRHLDALEKAAEHLQIGLVQLTEFHAGELLAEELRLVQSYLSEITGQFTSDDLLGNIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEXA_LEUCK
Sequence: MAIQESKQIQVLRFIHEAQLNNGYPPTVREVGEAVGLSSSSTIHGHIERLVKKGYLLKDASKPRARAIEVTDSGLEALGVSTTPGRIPVLGQVTAGAPILAVEEEATEFFPIPDNLMQFDGDMFMLNVRGNSMINIGILDGDKVIVRKQDNADNGDVVVAMNDDDEATVKRFFREADHFRLQPENDAMAPIILKQVAILGKVIGLYRDAIY
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: RUVB_STAA3
Sequence: MNERMVDQSMHSEETDFELSLRPTRLRQYIGQNSIKSNLEVFIKAAKLRHEPLDHVLLFGPPGLGKTTLSNIIANEMEVNIRTVSGPSLERPGDLAAILSGLQPGDVLFIDEIHRLSSVVEEVLYPAMEDFFLDIIIGKGDEARSIRIDLPPFTLVGATTRAGSLTGPLRDRFGVHLRLEYYNESDLKEIIIRTAEVLGTGIDEESAIELAKRSRGTPRVANRLLKRVRDFQQVNEDEQIYIETTKHALGLLQVDQHGLDYIDHKMMNCIIKQYNGGPVGLDTIAVTIGEERITIEDVYEPFLIQKGFLERTPRGRKATPLAYEHFAKSNEERE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: NANE_STAA3
Sequence: MLPHGLIVSCQALPDEPLHSSFIMSKMALAAYEGGAVGIRANTKEDILAIKETVDLPVIGIVKRDYDHSDVFITATSKEVDELIESQCEVIALDATLQQRPKETLDELVSYIRTHAPNVEIMADIATVEEAKNAARLGFDYIGTTLHGYTSYTQGQLLYQNDFQFLKDVLQSVDAKVIAEGNVITPDMYKRVMDLGVHCSVVGGAITRPKEITKRFVQIMED
What is the function of this protein?
Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).
What are the official names of this protein?
Putative N-acetylmannosamine-6-phosphate 2-epimerase, ManNAc-6-P epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanE family.
Protein: YCEQ_SALTI
Sequence: MSVACISYGNTAQLSGKQPGHYSPEKILSTGKDCNPQPANCLKNQYVLRHCCVDDRSDKMGYSAKLFVLTSFGAETASLFHC
What are the official names of this protein?
Uncharacterized protein YceQ.
Protein: RL36_CHLCV
Sequence: MKVSSSIKADPSKGDKLVRRKGRLYVINKKDPNRKQRQAGPARKK
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.