PharMolix/UniProtQA huggingface dataset:
Protein: LRCH3_HUMAN
Sequence: MAAAGLVAVAAAAEYSGTVASGGNLPGVHCGPSSGAGPGFGPGSWSRSLDRALEEAAVTGVLSLSGRKLREFPRGAANHDLTDTTRADLSRNRLSEIPIEACHFVSLENLNLYQNCIRYIPEAILNLQALTFLNISRNQLSTLPVHLCNLPLKVLIASNNKLVSLPEEIGHLRHLMELDVSCNEIQTIPSQIGNLEALRDLNVRRNHLVHLPEELAELPLIRLDFSCNKITTIPVCYRNLRHLQTITLDNNPLQSPPAQICIKGKVHIFKYLNIQACKIAPDLPDYDRRPLGFGSCHEELYSSRPYGALDSGFNSVDSGDKRWSGNEPTDEFSDLPLRVAEITKEQRLRRESQYQENRGSLVVTNGGVEHDLDQIDYIDSCTAEEEEAEVRQPKGPDPDSLSSQFMAYIEQRRISHEGSPVKPVAIREFQKTEDMRRYLHQNRVPAEPSSLLSLSASHNQLSHTDLELHQRREQLVERTRREAQLAALQYEEEKIRTKQIQRDAVLDFVKQKASQSPQKQHPLLDGVDGECPFPSRRSQHTDDSALCMSLSGLNQVGCAATLPHSSAFTPLKSDDRPNALLSSPATETVHHSPAYSFPAAIQRNQPQRPESFLFRAGVRAETNKGHASPLPPSAAPTTDSTDSITGQNSRQREEELELIDQLRKHIEYRLKVSLPCDLGAALTDGVVLCHLANHVRPRSVPSIHVPSPAVPKLTMAKCRRNVENFLEACRKIGVPQEQLCLPLHILEEKGLSQVAVTVQALLELAPPKQQQHQLSAV
What is the function of this protein?
As part of the DISP complex, may regulate the association of septins with actin and thereby regulate the actin cytoskeleton.
What are the official names of this protein?
DISP complex protein LRCH3, Leucine-rich repeat and calponin homology domain-containing protein 3.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_ALCBS
Sequence: MSGGEKEMPTNKERSPRYNRILLKLSGEALAGEEGFGIDPKVLDAISLEIGQLVGIGVQVGLVVGGGNLFRGAALQSAGLDRVAGDHMGMLATVMNGLALRDALERSNIRTRLMSAIPMSGVVEHYDHRNANRHLKNGEVVIFCAGTGNPFFTTDSAACLRGIEISADVVLKATKVDGVYNDDPVKNPDAVKYDALTYDEVLEKKLGVMDLTAICLCRDHSMPLRVFDMNKKGALLNLMLGGKEGTLVEAAQ
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HGPRT_STAAR
Sequence: MHNDLKEVLLTEEDIQNICKELGAQLTKDYQGKPLVCVGILKGSAMFMSDLIKRIDTHLSIDFMDVSSYHGGTESTGEVQIIKDLGSSIENKDVLIIEDILETGTTLKSITELLQSRKVNSLEIVTLLDKPNRRKADIEAKYVGKKIPDEFVVGYGLDYRELYRNLPYIGTLKPEVYSN
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.
What are the official names of this protein?
Hypoxanthine-guanine phosphoribosyltransferase, HGPRT, HGPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_METPP
Sequence: MARKTPIERYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAATTCFWKGMELAFPEHRINIIDTPGHVDFTIEVERSMRVLDGACMVYCAVGGVQPQSETVWRQANKYKVPRLAFVNKMDRTGANFYKVYDQMKVRLKANPVPIVLPIGAEENFTGVIDLIKMKAIIWDEASQGMKFNYEDIPADLQAESQKWRENMVEAAAEASEELMNKYLESGELTEAEIKFGIRTRTIAAEIQPMFCGTAFKNKGVQRMLDGVIDFMPSPIDIPPVPGHDDDDKEVVRRAADDEKFAALAFKLMTDPYVGQLTFVRVYSGVLKSGDSVFNPIRGKKERIGRILQMHANQREEIKEILAGDIAACVGLKEVTTGETLCDPDAIITLEKMIFPEPVISQAVEPKTKADQEKMGIALGRLAQEDPSFRVRTDEESGQTIISGMGELHLEIIVDRMKREFGVEANVGKPQVAYRETIRKPVSDIEGKFVRQSGGKGQYGHVVLKIEPQEPGKGFEFVDAIKGGVVPREFIPAVKKGVEDSLPNGVLAGFPVVDVKVTLTFGSYHEVDSNENAFKMAASLGFKDGCRKASPVILEPMMAVEVETPEDYAGNVMGDLSSRRGMVQGMDDMPGGGKAIKAEVPLSEMFGYSTTLRSMSQGRATYTMEFKHYSEAPKNVADAIITSRAK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCAP_I87A2
Sequence: MASQGTKRSYEQMETDGERQNATEIRASVGKMIDGIGRFYIQMCTELKLSDYEGRLIQNSLTVERMVLSAFDERRNRYLEEHPSAGKDPKKTGGPIYKRVGGRWMRELVLYDKEEIRRIWRQANNGDDATRGLTHMMIWHSNLNDTTYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGIGTMVMELIRMIKRGINDRNFWRGENGRKTRSAYERMCNILKGKFQTAAQRAMMDQVRESRNPGNAEIEDLIFSARSALILRGSVAHKSCLPACVYGPAVSSGYDFEKEGYSLVGIDPFKLLQNSQVYSLIRPNENPAHKSQLVWMACHSAAFEDLRLLSFIRGTKVSPRGKLSTRGVQIASNENMDNMESSTLELRSRYWAIRTRSGGNTNQQRASAGQISVQPTFSVQRNLPFEKSTVMAAFTGNTEGRTSDMRAEIIRMMEGAKPEEVSFRGRGVFELSDEKATNPIVPSFDMSNEGSYFFGDNAEEYDN
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: LEU1_BURCM
Sequence: MTDKLIIFDTTLRDGEQSPGASMTKEEKIRIAKHLERMKVDVIEAGFAASSNGDFDAIHTIAGLVKDSTICSLARANDKDIQRAADALKPANSARIHTFIATSPLHMEKKLRMTPDQVFEQARLAVRFARKFTDNVEFSPEDGSRSDLDFLCRVLEAVIAEGATTINIADTVGYGVPELYGNLVKTLRERIPNSDKAIFSVHCHNDLGMAVANSLAGVKIGGARQVECTINGLGERAGNTSLEEIVMAVKTRKDYFGLDVGLDTTQIVPTSKLVSQITGFVVQPNKAVVGANAFAHASGIHQDGVLKARDTYEIMRAEDVGWTANKIVLGKLSGRNAFKQRLQELGVSLDSETELNAAFMRFKDLADRKSDIFDEDIIAIVSEESAFAQEQEHYKFVSLSQRSETGEQPQAKVVLALDGKEVTGEARGNGPVDATFNAIEGEVGSGSELLLYSVNAITTGTQAQGEVTVRLSKSGRIVNGVGTDPDIVAASAKAYIAALNKLHSKDDKLNPQRS
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: TNNC2_CAEEL
Sequence: MGDVVADALEKLSADQIEQFRKYFNMFDKEGKGYIRATQVGQILRTMGQAFEERDLKQLIKEFDADGSGEIEFEEFAAMVANFVVNNENDEGLEEELREAFRLYDKEGNGYINVSDLRDILRALDDNVSEEELDEMIAEIDADGSGTVDFDEFMEMMSGE
What are the official names of this protein?
Troponin C, isoform 2.
What is the protein family that this protein belongs to?
Belongs to the troponin C family.
Protein: DNAK_RHIEC
Sequence: MAKVIGIDLGTTNSCVAVMDGKDAKVIENAEGARTTPSMVAFSDDGERLVGQPAKRQAVTNPTNTLFAVKRLIGRRYEDPTVEKDKHLVPFSIVKGDNGDAWVEANGKGYSPAQISAMILQKMKETAESYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVLRIINEPTAAALAYGLDKKDGKTIAVYDLGGGTFDISILEIGDGVFEVKSTNGDTFLGGEDFDMRLVEYLVAEFKKDNGIDLKNDKLALQRLKEAAEKAKIELSSSQQTEINLPFITADASGPKHLTLKLTRAKLESLVDDLVQRTIAPCKAALKDAGVTAAEIDEVVLVGGMSRMPKVQEVVKQLFGKEPHKGVNPDEVVALGAAIQAGVLQGDVKDVLLLDVTPLSLGIETLGGVFTRLIERNTTIPTKKSQTFSTAEDNQQAVTIRVSQGEREMAADNKLLGQFDLVGLPPSPRGVPQIEVTFDIDANGIVQVSAKDKGTGKEQQIRIQASGGLSDADIEKMVKDAESHAAEDKKRRETVEAKNQAESLIHSTEKSLKDYGDKVSEADRTAISDAIAALKSSTEATEADAEDIKAKTQTLMEVSMKLGQAIYEAQQAEGGAAADASAEGGDNVVDADYEEIKDDDRKKSA
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: HEMH_YERPG
Sequence: MMQSKPGVLMVNLGTPDAPTSKAIKRYLAEFLSDRRVVDTSPLLWWPLLHGVILPLRSPRVAKLYQSVWMEEGSPLLVYSRRQQKALAARMPDIPVELGMSYGSPNLPEAIEKLLAQGVTNLVILPLYPQYSCSTSAAVWDAVARVLKGYRRLPSISFIRDYAEHPAYISALKQSVERSFAEHGQPDRLVMSFHGIPKRYAQLGDDYPIRCEDTSRALRAALPLPAEKIIMTYQSRFGREPWLTPYTDETLKSLPSQGVKHIQLICPGFSADCLETLEEIKEQNREFFLHAGGEKFEYIPALNDDEGHIALLEQLIRHNI
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIMT_METTH
Sequence: MMDERRRMVQDLMERGYIKSEAVRRAMERVPREEFVPEDEMHRAYMDMPLPIGEGQTISAPHMVAMIAEILDLEPGMKVLEIGTGCGYNAAVIAEIIGPEGHLYTVERIGILYERARKKLRSLGYDNITVIHGDGSQGFADEAPYSRIYVTAAAPYIPDPLMKQLEIGGKLLIPVGSDKFYQELVLIERTSADDYRSRNLGGVAFVPLIGKHGWKFH
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins (By similarity).
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BUK_BACC7
Sequence: MSVNRILVINPGSTSTKIGVFDNERPVLEETIRHDEEQIGKYKRIIDQYEFRKETILEVLHSHGINISKLNAVCGRGGLLRPIEGGTYTVNDAMLEDLKNGFSGHHASNLGGILAYEIASGLNIPAFIVDPVVVDEMEPIARISGIAGMERKSIFHALNQKAVARKVAEQLNHKYEDLNLLVTHMGGGITVGAHKKGRVIDVNNGLNGEGPFSPERAGTVPVGQLVEMCFSGEYYRDEMIKKLVGQGGLVSLIGTNDAIKVEQMVEKGDPEATLIYKAMAYQVAKEIGGASAVLHGKIDAIVLTGGLAYSKILVDEIKERVDWIADVIVHPGEDELQALAEGALRVLREEEAPKEYIVREKETVARG
What are the official names of this protein?
Probable butyrate kinase, BK, Branched-chain carboxylic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_PSEA8
Sequence: MPTDAKRPLQLNDQGQLRHFISLDGLPRELLTEILDTADSFLEVGARAVKKVPLLRGKTVCNVFFENSTRTRTTFELAAQRLSADVISLNVSTSSTSKGETLTDTLRNLEAMAADMFVVRHSDSGAAHFIAEHVSPNVAVINGGDGRHAHPTQGMLDMLTIRRHKGNFEQLSVAIVGDILHSRVARSNMLALKTLGCPDIRVIAPRTLLPIGLEEQYGVRVFTNADEGLKDVDVVIMLRLQRERMQGGLLPSEGEFFKLYGLTEKRLKLAKPDAIVMHPGPINRGVEIESAVADGAQSVILNQVTYGIAIRMAVLSMAMSGQNTQRQLEQEDAE
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: UCRI3_TOBAC
Sequence: MLRIAGRKLSSSAATRSSSAFFTRNPFTFTDDSSSPARSPSPASLASQFLDQFRGFSSNSVSPAHQTGLVSDLPATVAAIKNPSSKIVYDDSNHERYPPGDPSKRAFAYFVLTGGRFVYASLVRLLILKFVLSMSASKDVLALASLEVDLSSIEPGTTVTVKWRGKPVFIRRRTEEDINLANSVDLGSLRDPQQDAERVKNPEWLVVIGVCTHLGCIPLPNAGDFGGWFCPCHGSHYDISGRIRKGPAPYNLEVPTYSFMEENKLLIG
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol.  In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.  The Rieske protein is a catalytic core subunit containing a [2Fe-2S] iron-sulfur cluster.  It cycles between 2 conformational states during catalysis to transfer electrons from the quinol bound in the Q(0) site in cytochrome b to cytochrome c1.
What are the official names of this protein?
Cytochrome b-c1 complex subunit Rieske-3, mitochondrial, Complex III subunit 5-3, Rieske iron-sulfur protein 3, RISP3, Ubiquinol-cytochrome c reductase iron-sulfur subunit 3.
What is the protein family that this protein belongs to?
Belongs to the Rieske iron-sulfur protein family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: NUBP2_DROGR
Sequence: MLDKVKNVIVVLSGKGGVGKSTVSTQLALALRATGHKVGLLDIDLCGPSVPYLLGLEGRDIFQCDDGWVPIYTDESKTLAVMSIGFLLKNRTDPVIWRGPKKTMMIKQFLSDVKWDELDYLIIDTPPGTSDEHITVMECLREVPCNGAIIVTTPQGVALDDVRKEITFCKKTGIKLLGIVENMSGFVCPHCTECTNIFSSNGGAELANLAQVPHLGTLPIDPRVGVLAGSTASALDELPDSSTAQILRGIVQHLDALTAVPAIA
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery.  Required for maturation of extramitochondrial Fe-S proteins.  The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor NUBP2 homolog.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CALU_PONAB
Sequence: MDLRQFLMCLSLCTAFALSKPTEKKDRVHHEPQLSDKVHNDAQSFDYDHDAFLGAEEAKTFDQLTPEESKERLGKIVSKIDDDKDGFVTVDELKDWIKFAQKRWIYEDVERQWKGHDLNEDGLVSWEEYKNATYGYVLDDPDPDDGFNYKQMMVRDERRFKMADKDGDLIATKEEFTAFLHPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYIGDMYSHDGNTDEPEWVKTEREQFVEFRDKNRDGKMDKEETKDWILPSDYDHAEAEARHLVYESDQNKDGKLTKEEIVDKYDLFVGSQATDFGEALVRHDEF
What is the function of this protein?
Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues.  Seems to inhibit gamma-carboxylase GGCX.  Binds 7 calcium ions with a low affinity (By similarity).
What are the official names of this protein?
Calumenin.
What is the protein family that this protein belongs to?
Belongs to the CREC family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane. Golgi apparatus. Secreted. Melanosome. Sarcoplasmic reticulum lumen.
Protein: YCF28_PORPU
Sequence: MNNHYLNQGCSFEKVSKNILKKNSHCNPWLSFFNQQDSEHQIFSLKQNDIIIFDVNSKLYIILAGCLIVKKVFRNRKKIILNVLTSEDSFGHTQFASNRFYYEVEALDVAQVLSIEYSIIMNICQNYPNFSVFLVNHLLLCSIKANHFMEIISHKSITNRLISLLLLLSEHNGISQNNGILIDLTITHKVLAQIIGSNRVSITRIISKLIHTKFISMQKKKVIIHDPILLSQRFSNR
What are the official names of this protein?
Putative HTH-type transcriptional regulator ycf28.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NIFW_ZYMMO
Sequence: MSFADTLRQLSSAEDFFSALHVDYDPQILNVARLHILRKMRLYLEADKGDLADESLQKQQYQHYLAQAYNDFVHSSPIKERLFKVHQEAVKPVKLPMVKLTSLTMPPE
What is the function of this protein?
May protect the nitrogenase Fe-Mo protein from oxidative damage.
What are the official names of this protein?
Nitrogenase-stabilizing/protective protein NifW.
What is the protein family that this protein belongs to?
Belongs to the NifW family.
Protein: PSBM_SORBI
Sequence: MEVNILAFIATALFILVPTAFLLIIYVKTASQND
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface.
What are the official names of this protein?
Photosystem II reaction center protein M, PSII-M.
What is the protein family that this protein belongs to?
Belongs to the PsbM family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CYF_GLOVI
Sequence: MKKQWIAGAFGLTAALAGLVSVPQSALAWPSFAAGYEEARESSGKIVCANCHLAVKPTEIEVPQSVLPGKVFDLKIHVPYDTKIQQVGADGSPAPMQIGAYIQLPEGFTVADEKEWSAEAKESIEKYGGVTPLYADKPERSNILIINQIDGSTVPGQEFIVPVKPPDPNAKDAKVNFGKYGVYVGANRGRGQVYSNGVASNTAQYNAPVAGTISAVQTGVTFTDKLQYGLGTEATDFEYTNGTRVTITDEKGKASIVNIPPGPKLLDTVKQGAQIKAGQPLTNDPNVGGYGQEERDIVLQDPQRVTWLVAFLAAAFICQLLLVLKKKQVEKVQEFEAQKQGL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome f family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PRMA_ALISL
Sequence: MPWIQVKLNATSENAELISDMLVEETGALSVTFLDAKDTPIFEPLPGETRLWGETDIVALYDAETDMDLVITQLKASAVLDDNFAYKIEQLEDKDWEREWMDNFHPMKFGERLWICPSWREIPEPDAINVMLDPGLAFGTGTHATTALCLEWLESIDLTGKTVIDFGCGSGILAIAAIKLGAAKVVGIDIDPQAITASKDNATRNGVAEQLTLFLPQDQPENLVADVVVANILAAPLRELSSIITAHVKPGGALAMSGVLDTQANNVASYYSDNFTLDAIAEQQEWCRISGIKK
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUD_HAEIN
Sequence: MAGFKQLSGLVVPLDAANVDTDAIIPKQFLQAITRIGFGKHLFHEWRYLDVEGTKPNPEFVLNYPQYQGATILLARKNLGCGSSREHAPWALADYGFKVMIAPSFADIFYNNSLNNHMLPIRLSEEEVEEIFQWVWANEGKQIHVDLEAMTVTVGDKVYTFELDEFRRHCLLNGLDNIGLTLQHEDKISAYEKNIPAFLR
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: EFTU_AGRFC
Sequence: MAKSKFERNKPHVNIGTIGHVDHGKTSLTAAITKYFGEFKAYDQIDAAPEEKARGITISTAHVEYETPARHYAHVDCPGHADYVKNMITGAAQMDGAILVCSAADGPMPQTREHILLARQVGVPAIVVFLNKVDQVDDAELLELVELEVRELLSSYDFPGDDIPIIKGSALAALEDSDKKIGEDAIRELMAAVDAYIPTPERPIDQPFLMPIEDVFSISGRGTVVTGRVERGIVKVGEEVEIVGIRPTSKTTVTGVEMFRKLLDQGQAGDNIGALVRGVTRDGVERGQILCKPGSVKPHKKFMAEAYILTKEEGGRHTPFFTNYRPQFYFRTTDVTGIVSLPEGTEMVMPGDNVTVEVELIVPIAMEEKLRFAIREGGRTVGAGIVASIVE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LVGA_LEGPN
Sequence: MADGDIEIKAGFVDTDLDDRKLTMIDDLNNPLAIVERVYLIWWHWADFHLHVISPHIDTITPAIVIEPELISGSNDHEFVYSIHDSGSKLSTSKSQDMFSAGMSMCKLFYTIEKMVHILVDRLKSGGVSMEEEVQIAFAGHEIAQRKAFESIINLPYNVVVTNFDPGIWGEKYLQNVKRLADKGYGYPPESPRENYKHPVSSATTARK
What is the function of this protein?
Component of the Dot/Icm type IVB secretion system (T4BSS), which is used to inject bacterial effector proteins into eukaryotic host cells (By similarity).  Part of a subcomplex which recruits effector proteins and delivers them to the core transmembrane subcomplex (By similarity).  Is a critical subunit for binding a subset of effector proteins (By similarity).  Recognizes more than one type of binding motif (By similarity).  May be a critical factor that confers host specificity (By similarity).  Necessary for full virulence of the bacterium in guinea pigs and presumably humans (PubMed:12704109).
What are the official names of this protein?
Type 4 adapter protein LvgA, Virulence factor LvgA.
What are the subcellular locations of this protein?
Cytoplasm. Note=At least some of the protein may be surface expressed.
Protein: RL27_PELPB
Sequence: MAHKKGGGSTKNGRDSNPKYLGVKAAGGSTVAAGTIILRQRGTVIKPGMNAGLGRDHTIFALIDGVVTFRNGRNNKKQVNILPC
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: OAZ_YEAST
Sequence: MYEVIQKRKTKIINVLQSPELMRLIEDPSNLGISLHFPVSSLLKSNKCTPMPKLSTYSLASGGFKDWCADIPLDVPPEIDIIDFYWDVILCMESQFILDYNVPSKNKGNNQKSVAKLLKNKLVNDMKTTLKRLIYNENTKQYKNNNSHDGYNWRKLGSQYFILYLPLFTQELIWCKLNENYFHVVLPSLLNSRNVHDNHSTYINKDWLLALLELTSNLNQNFKFEYMKLRLYILRDDLINNGLDLLKNLNWVGGKLIKNEDREVLLNSTDLATDSISHLLGDENFVILEFEC
What is the function of this protein?
Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis in response to increased intracellular polyamine levels (PubMed:15538383).  Binds to ODC/SPE1 monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin-independent proteolytic destruction by the 26S proteasome (PubMed:18089576).
What are the official names of this protein?
Ornithine decarboxylase antizyme, ODC-Az.
What is the protein family that this protein belongs to?
Belongs to the ODC antizyme family.
Protein: AROK_STAAM
Sequence: MNHDKSPIILIGFMGTGKSTIGKYVADEQNLSFIDIDSYIEEKYKLTIPEIFSKHGEQYFRNLEFTCLQECINTADIIATGGGIIESEEAFNFLKNQKNIIWLDCNIDIIYSRINDDPHRPNANNKTIKQLNDLYCSRILRYNEIAFKKFDSHLLSISEIYYELLNLIKASDQY
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_ECODH
Sequence: MSITKDQIIEAVAAMSVMDVVELISAMEEKFGVSAAAAVAVAAGPVEAAEEKTEFDVILKAAGANKVAVIKAVRGATGLGLKEAKDLVESAPAALKEGVSKDDAEALKKALEEAGAEVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: CK1_ARATH
Sequence: MAIKTKTSLIPSCSSPEDLKRVLQTLGSSWGDVVEDLERLEVVPLKGAMTNEVYQINWPTLNGEDVHRKVLVRIYGDGVDLFFNRGDEIKTFECMSHHGYGPKLLGRFSDGRLEEFIHARTLSADDLRVAETSDFIAAKLREFHKLDMPGPKNVLLWERLRTWLKEAKNLASPIEMDKYRLEGLENEINLLEERLTRDDQEIGFCHNDLQYGNVMIDEVTNAITIIDYEYSSFNPIAYDIANHFCEMAANYHSDTPHVLDYTLYPGEGERRRFISTYLGSTGNATSDKEVERLLKDAESYTLANHIFWGLWGIISGHVNKIEFDYMEYARQRFEQYWLRKPLLLEG
What is the function of this protein?
Involved in phospholipid biosynthesis.  Catalyzes the first step in phosphatidylcholine biosynthesis (By similarity).
What are the official names of this protein?
Probable choline kinase 1, AtCK1.
What is the protein family that this protein belongs to?
Belongs to the choline/ethanolamine kinase family.