PharMolix/UniProtQA huggingface dataset:
Protein: LIPA_PROMH
Sequence: MSKPIQMERGVKYRDADKMALIPVKTIVTEREELLRKPEWMKIKLPADSSKIQGIKAAMRKNGLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPFCDVAHGRPNAPDPQEPIKLAQTIKDMGLRYVVITSVDRDDLRDGGAQHFADCITAIREKNPNIRIETLVPDFRGRMDKALEILTDTPPDVFNHNLENVPRVYRQVRPGANYQWSLTLLERFKQAHPNIPTKSGLMVGLGETNEEIIDVMRDLRKHGVTMLTLGQYLQPSRHHLPVQRYVSPDEFEYMKEQALAMGFTHAACGPFVRSSYHADLQAQGIEVK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBID_LISW6
Sequence: MEDFIYYNGKKYRKGYTTGTCAAAAAKACVEMILTQEEVSAVQVTTTGGTILEIPVAHQQFSKKRATAAVQKDGGDDIDATHGMWIFVDVELTNSTEVVLDGGVGIGRATQKGISVAVGEAAINPAPRKNILEAVRKSLGEHRGANILVYAPEGEERAKRTMNSNLGIIGGISILGTTGIVTPMSDEGWKKSLSMELEMKRNQGLEQIILVPGNYGDDFVQHTLGFSSNNIVSMSNFVGYMLKETQRLAFKKVLMVGHFGKLVKVSAGIFTTYSKDADARAEILVANLALLGAPLSLLQEVEKCNTTEAAGELIEEAGYTHVYEVIAQKIKARSERFLKFTKPSVEIDVVTFSTERGLLATTKDIDVLREEWQ
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: ATPD_PROM3
Sequence: MPLLNTITTPYAEAFLQVAESRKEVDQVVDQAKAVLALWNDCPELSGAMASPVLEVEAKKAALQKLFANQVTPSFLNLLKLLADRQRIGVLDAVLERLIELYREQRNIALATVTSAAELSEQQQAALQKKVQAVANTDKLEINLKIDPDLIGGFVVNVGSKVIDASVAGQVRRLGLALAKVS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: NADD_SALPA
Sequence: MKSLQALFGGTFDPVHYGHLKPVETLANLIGLSRVIIMPNNVPPHRPQPEASSAQRKYMLELAIADKPLFTLDERELQRNAPSYTAQTLKAWREEQGPEAPLAFIIGQDSLLNFPTWHDYDTILDNTHLIVCRRPGYPLEMTQAQHQQWLEQHLTHTPDDLHQLPAGKIYLAETPWLNISATLIRERLEKGESCDDLLPENVLNYINQQGLYR
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: TDB01_HUMAN
Sequence: GTGG
What is the function of this protein?
D region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition (PubMed:24600447).  Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.  Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333).  Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.  In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.  The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462).  The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement.  This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells.  Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585).
What are the official names of this protein?
T cell receptor beta diversity 1.
What are the subcellular locations of this protein?
Cell membrane.
Protein: DCUP_ACIBT
Sequence: MTTLKNDRFLRALLREPVDTTPIWMMRQAGRYLPEYRETRSKAGDFLSLCKNTEFACEVTLQPLRRYDLDAAILFSDILTIPDALGLGLYFETGEGPKFHKTVRTEQDVANLPKLNAKADLDYVMNAVSTIRSALGGQVPLIGFSGSPWTLATYMVEGGSSKEFRFTKQMMYAQPEVLHALLDHLADSVIDYLNAQIDAGAQAIQIFDSWGGALAHREYVEFSLNYMKKIIAGLQREKDGRRIPVIVFTKGGGQWLEPMITTGADALGLDWTTPLNTARNVVSGRVALQGNLDPAVLYGSAASIEKAVKAMLDDAYANGEKTGYVANLGHGITQWVDPAQPKIFVDTVHEYSAKYLG
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIG_PSEPG
Sequence: MSNVDRAEIAKFEALAHRWWDRESEFKPLHEINPLRVNWIDERASLAGKKVLDVGCGGGILSEAMALRGATVTGIDMGEAPLAVAQLHQLESGVQVEYRQITAEALAEEMPEQFDVVTCLEMLEHVPDPSSVIRACYRMVKPGGQVFFSTINRNPKAYLLAIVGAEYILKMLPRGTHDFKKFIRPSELGAWSRDAGLQVKDIIGLTYNPLTKHYKLNSDVDVNYMIQTLREE
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: NUOD_FRATN
Sequence: MAEYKNYTLNFGPVHPAAHGVLRLILELDGENVVRADPHVGLLHRGTEKLAEFKPYNQSIGYMDRLDYVSMMCNEHAYVMAIEKLLQLEVPERAKYIRVMFAEMTRILNHLLWVAACGIDLGAMTVFLYAFRVREDLFDCYEAVSGARMHAAYFRPGGVARDLPTQMPQYQKTRFTSKRKAKKLNEPRQGSMLDFLDHFVVDFEKSLDEIDTLLTDNRLWKQRTVDIGTVTAERAKELGFTGPMLRGSGVAWDLRKTQPYEVYHKLEFDIPIGANGDCYDRYLVRMAEMRESNKLIKQCVDWLRANPGPVLSDNHKVAPPKRNAMKNNMEELIHHFKLFSEGYCTPEGEVYVGTEHPKGEFGVYIKSDGANKPYRLKMRAPGFAHISAMDELLSGHMLADTPAIISTIDVVFGDVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: OMPA1_NEIMC
Sequence: MRKKLTALVLSALPLAAVADVSLYGEIKAGVEGRNIQAQLTEQPQVTNGVQGNQVKVTKAKSRIRTKISDFGSFIGFKGSEDLGEGLKAVWQLEQDVSVAGGGASQWGNRESFIGLAGEFGTLRAGRVANQFDDASQAINPWDSNNDVASQLGIFKRHDDMPVSVRYDSPEFSGFSGSVQFVPAQNSKSAYKPAYYTKDTNNNLTLVPAVVGKPGSDVYYAGLNYKNGGFAGNYAFKYARHANVGRNAFELFLIGSATSDEAKGTDPLKNHQVHRLTGGYEEGGLNLALAAQLDLSENGDKAKTKNSTTEIAATASYRFGNAVPRISYAHGFDLIERGKKGENTSYDQIIAGVDYDFSKRTSAIVSGAWLKRNTGIGNYTQINAASVGLRHKF
What is the function of this protein?
Serves as a slightly cation selective porin.  Major antigen on the gonococcal cell surface and it may have pathogenic properties in addition to its porin activity.
What are the official names of this protein?
Major outer membrane protein P.IA, PIA, Protein IA, Class 1 protein.
What is the protein family that this protein belongs to?
Belongs to the Gram-negative porin family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: DER_FRATO
Sequence: MSFLVAIVGRANVGKSTLFNVLTNSHDALVFDFEGVTRDRQYGQAKYDDLDYLVVDTGGISDKDVGFDEFMAKQSQIAIDEANLVFFVVDGRSGLTTGDEYVASLLRQKDKKVVVVVNKVDGTDEEAAMAEFYSFGFDKVFAISAAHRRNTQKLVDKFLKKPLNEYYQDYTQTQEHKEQQRHGIHFSLIGRPNVGKSTLTNRMLGEDRVVVFDMPGTTIDSVSIPFERHGQKYTIVDTAGVRKRGKVKQTLEKFSVIKTLQAIQDSNVVVAVVDARQGISDQDLSLIHFAIKNGRALVLAVNKWDGMTEEDRIQVKQDLKRKLFFLQDYVDIHFISALYGTNVGHVFESIDTAYACANKKITTADATRLMQLAVEAHSPPMVGKFRIKLKYAHVGGHNPPVIVIHGNQVSRLPNSYKRYLENFFREALDFRGTPIVFEFKQSENPFADRKNKRSKDEGSKSKKVK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: PYRI_ECO57
Sequence: MTHDNKLQVEAIKRGTVIDHIPAQIGFKLLSLFKLTETDQRITIGLNLPSGEMGRKDLIKIENTFLSEDQVDQLALYAPQATVNRIDNYEVVGKSRPSLPERIDNVLVCPNSNCISHAEPVSSSFAVRKRANDIALKCKYCEKEFSHNVVLAN
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: THID_SALTY
Sequence: MQRINALTIAGTDPSGGAGIQADLKTFSALGAYGCSVITALVAQNTCGVQSVYRIEPDFVAAQLDSVFSDVRIDTTKIGMLAETDIVEAVAERLQRHHVRNVVLDTVMLAKSGDPLLSPSAIETLRVRLLPQVSLITPNLPEAAALLDAPHARTEQEMLAQGRALLAMGCEAVLMKGGHLEDAQSPDWLFTREGEQRFSAPRVNTKNTHGTGCTLSAALAALRPRHRSWGETVNEAKAWLSAALAQADTLEVGKGIGPVHHFHAWW
What is the function of this protein?
Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.
What are the official names of this protein?
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase, Hydroxymethylpyrimidine kinase, HMP kinase, Hydroxymethylpyrimidine phosphate kinase, HMP-P kinase, HMP-phosphate kinase, HMPP kinase.
What is the protein family that this protein belongs to?
Belongs to the ThiD family.
Protein: ATPF2_NEOYE
Sequence: MIDLPFLLAEEIEGGLFDFNGTLPLMALQFLTLMVLLNTIFYKPVTKVLDERDEYIRTTLTTASSMLVKADELAAKYEEDLSEARRNAQLKIASSQKEAQNIVSEDIKKAQLNAEKLIAEASKQLNVQKEEALKTLENQVDTLSDQIKVKLLSSQS
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).  The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
What are the official names of this protein?
ATP synthase subunit b', chloroplastic, ATP synthase F(0) sector subunit b', ATPase subunit II.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: NUOB_STRM5
Sequence: MGVIQTLDGLMNNPTPEGRVDDILRPEGDNPLLEKGFVTTSVDALLNWARTGSMWPMTFGLACCAVEMMHAGAARLDLDRYGVVFRPSPRQSDVMIVAGTLVNKMAPALRKVYDQMPDPKWVISMGSCANGGGYYHYSYSVVRGCDRVVPVDVYVPGCPPTAEALVYGILQLQKKIWRTQTIAR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PHYA5_AVESA
Sequence: MSSSRPASSSSSRNRQSSQARVLAQTTLDAELNAEYEESGDSFDYSKLVEAQRDGPPVQQGRSEKVIAYLQHIQKGKLIQTFGCLLALDEKSFNVIAFSENAPEMLTTVSHAVPSVDDPPRLGIGTNVRSLFSDQGATALHKALGFADVSLLNPILVQCKTSGKPFYAIVHRATGCLVVDFEPVKPTEFPATAAGALQSYKLAAKAISKIQSLPGGSMEMLCNTVVKEVFDLTGYDRVMAYKFHEDDHGEVFSEITKPGLEPYLGLHYPATDIPQAARFLFMKNKVRMICDCRARSIKVIEAEALPFDISLCGSALRAPHSCHLQYMENMNSIASLVMAVVVNENEEDDEAESEQPAQQQKKKKLWGLLVCHHESPRYVPFPLRYACEFLAQVFAVHVNREFELEKQLREKNILKMQTMLSDMLFREASPLTIVSGNPNIMDLVKCDGAALLYGGKVWRLRNAPTESQIHDIAFWLSDVHRDSTGLSTDSLHDAG
What is the function of this protein?
Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light: the Pr form that absorbs maximally in the red region of the spectrum and the Pfr form that absorbs maximally in the far-red region.  Photoconversion of Pr to Pfr induces an array of morphogenic responses, whereas reconversion of Pfr to Pr cancels the induction of those responses.  Pfr controls the expression of a number of nuclear genes including those encoding the small subunit of ribulose-bisphosphate carboxylase, chlorophyll A/B binding protein, protochlorophyllide reductase, rRNA, etc.  It also controls the expression of its own gene(s) in a negative feedback fashion.
What are the official names of this protein?
Phytochrome A type 5, AP5.
What is the protein family that this protein belongs to?
Belongs to the phytochrome family.
Protein: LEXA_VIBCH
Sequence: MKPLTPRQQEVFDLIKSKIDETGMPPTRAEIAKELGFRSANAAEEHLKALARKQVIEMVPGASRGIRILVDNAANEEEAETGLPLIGRVAAGEPILAQEHVEAHYQVDPSMFRPQADFLLRVHGESMKNIGILDGDLLAVHKTQDVRNGQVVVARVEDDVTVKRLERKGSKVFLHAENEEFAPIEVDLAAQSLTIEGIAVGVIRNSTWM
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: RL17_COLP3
Sequence: MRHRQSGRQLNRNSSHRQAMFRNMASSLVKHGVIKTTVAKAKELRRVLEPLITLAKTDSVANRRLAFARTQDKEVVGILFNELGARYQERPGGYTRILKCGFRTGDKAPMAYIELVDRPVVEDAPEVVEESAEA
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: T231E_BACTF
Sequence: MNLSIQGELQLFAEELHQHLTPSFLENLARELTFVKRKRKFSGHDLAIICVWVSQRVASDSLVRLCSQLHAVTGTLMSPEGLNKRFNKKAVCFLKHIFSTLLKNKICETSLIPSSSITYFQRIRILDATIFQVPKHLANVYPGSGGCAQTAGIKIQLEYDLHSGQFLNFQVEPGKNNDKTFGTECLATLRPGDLCIRDLGYYSLDDLDQMDQRGVYYISRLKLNNMVYIKNEFPEYFRNGIVKKQSQYIKVDLEHIMNTLKPGQVHEITEAYIGKDKKLFTRVIIYRLTEKQLRERKKKQVYTESKKGITYSEKSKRLAGMNIYVTNTPLEWVPMEQIHDFYSLRWQIEIIFKTWKSLFQIHDWQNIKRERLECHIYGKLIAIFLCSSTMFKMRQLILQKKKRELSEYKAIGMIQDHLYILYQAIQQNTQEITRILIRLFHLLQKNGRKSHRYEKKTVFDILGVVYEYTGLIKQKKIA
What is the function of this protein?
Involved in the transposition of the insertion sequence.
What are the official names of this protein?
Transposase for insertion sequence element IS231E.
What is the protein family that this protein belongs to?
Belongs to the transposase 11 family.
Protein: RL20_CLAM3
Sequence: MARVKRAVNAHKKRRVILERAAGYRGQRSRLYRKAKEQVTHSLVYAYRDRRAKKGEFRRLWIQRINAAARANGLTYNRLIQGLSLAGVQVDRRILAELAVHEPATFASLVQTAKAALPANTSAPKVAANA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: MURG_ACIF2
Sequence: MADSVLIAAGGTGGHVFPALAVADALRAQGVEVTFAGTATGMEARLVPERGYTLHTLDMQGLRGKGIRRWLRAPWRVSRAILQARRILRQTRSHVVLGMGGYVTAPVGIAAWTLGRPLCLHEQNAVAGLSNRLLAPLARRVFLGFPGARLARGEWVGNPVREAIHALPTPQERFHDRKGPVRLLIMGGSQGAQVLNAVSAAALSGMTDAERPAIWHQTGRDHAESTRAAYAQARIDAKVEPFIDDMAAALGWADLALCRAGAATIAELAAAGLGAILIPFPFAVDDHQAANARFLEKAGAARMLRQEGLDALQLRDVLRPLLADPELRLRWAEAARRQAKGDAAATVAAACIECAGGIDA
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL36_SALPC
Sequence: MQVLNSLRNAKQRHPDCQIVKRKGRLYVICKTNPRFKAVQGRKKRR
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: DGOD2_ECOSM
Sequence: MKITKITTYRLPPRWMFLKIETDEGVVGWGEPVIEGRARTVEAAVHELGDYLIGQDPSRINDLWQVMYRAGFYRGGPILMSAIAGIDQALWDIKGKVLNAPVWQLMGGLVRDKIKAYSWVGGDRPADVIDGIKTLREIGFDTFKLNGCEELGLIDNSRAVDAAVNTVAQIREAFGNQIEFGLDFHGRVSAPMAKVLIKELEPYRPLFIEEPVLAEQAEYYPKLAAQTHIPLAAGERMFSRFDFKRVLEAGGISILQPDLSHAGGITECYKIAGMAEAYDVTLAPHCPLGPIALAACLHIDFVSYNAVLQEQSMGIHYNKGAELLDFVKNKEDFSMVGGFFKPLTKPGLGVEIDEAKVIEFSKNAPDWRNPLWRHEDNSVAEW
What is the function of this protein?
Catalyzes the dehydration of D-galactonate to 2-keto-3-deoxy-D-galactonate.
What are the official names of this protein?
D-galactonate dehydratase 2, GalD 2.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
Protein: NIRD_ECO57
Sequence: MSQWKDICKIDDILPETGVCALLGDEQVAIFRPYHSDQVFAISNIDPFFESSVLSRGLIAEHQGELWVASPLKKQRFRLSDGLCMEDEQFSVKHYEARVKDGVVQLRG
What is the function of this protein?
Required for activity of the reductase.
What are the official names of this protein?
Nitrite reductase (NADH) small subunit.
What is the protein family that this protein belongs to?
To B.subtilis NasE.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPO4_CLOD6
Sequence: MKHYRKIIHIDMDAFYASIEQRDNKKLKGRPVIVGGNPQSRGVVATCSYEARKFGIHSAMPSAVAYNRCPYAVFVRPRFDVYKSVSEKIRDIFYRYTDLVEPLSLDEAYLDVTKNKKNIDSSIEIAKQIKKDIFREVGLTSSAGVSYNKFLAKIASDLRKPNGLTVITEENAQDFLDKLPVNKFFGVGKVTSNTLKNLGIKTGYDLRCLNLFELENIFKKRGYELYKFARGIDDRPVEPNRVRKSVGAETTLSHNLDIDEEETRNILDELCEEVCHRLKNSEKFGKTLTLKIKYEDFTKITRSLSLEHYIDEYNDIRSGVDNLLRNVEVNGKQIRLLGVTISNLSDKKETYKDITLFEYMDSIQM
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF4E3_HUMAN
Sequence: MALPPAAAPPAGAREPPGSRAAAAAAAPEPPLGLQQLSALQPEPGGVPLHSSWTFWLDRSLPGATAAECASNLKKIYTVQTVQIFWSVYNNIPPVTSLPLRCSYHLMRGERRPLWEEESNAKGGVWKMKVPKDSTSTVWKELLLATIGEQFTDCAAADDEVIGVSVSVRDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAVFYKPHEEHHAFEGGRGKH
What is the function of this protein?
Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis.  May act as an inhibitor of EIF4E1 activity (By similarity).
What are the official names of this protein?
Eukaryotic translation initiation factor 4E type 3, eIF-4E type 3, eIF-4E3, eIF4E type 3, eIF4E-3.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic initiation factor 4E family.
Protein: ADEC_METJA
Sequence: MIVFKNTKIIDVYTGEVVKGNVAVERDKISFVDLNDEIDKIIEKIKEDVKVIDLKGKYLSPTFIDGHIHIESSHLIPSEFEKFVLKSGVSKVVIDPHEIANIAGKEGILFMLNDAKILDVYVMLPSCVPATNLETSGAEITAENIEELILLDNVLGLGEVMNYPAVINEDEEMLKKIEVAKKYNKLIDGHCPKLKGWELNKYISHGIMSDHESVDEDEALEKLRLGLKLMIREGTASKNIYLLNICKKIKDFRNIMLVSDDVCIKDLDGYMLNILRKATNYVSPIEAIQMVTINPANYFGFDVGIKAGNEASFVIFEDLDNFKVYNIVIKGRFLDDVLNELNKNKKRKIPEKLMNTLKYQYKNEGDFLIKGIDYKERDGFIRVIKPLKDSLITEELIFSTEEIKILLNENAINKIFVIERHKNTGNIGKGLIYNFLEEGALASSYAHDSHNVIAIGNNEKDLALAVNKLKDIGGGFIAAKDGEVVEYLPLPVGGIMGDDGKYIAEKINALYKKIEGWSSFENPFLSMSFFSLPVIPELKITDKGLVKDMQLVDLFI
What are the official names of this protein?
Adenine deaminase, Adenase, Adenine aminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: NUCS_CORGL
Sequence: MRLVIARCSVDYVGRLEAHLPSADRLLMVKADGSVSIHADDRAYKPLNWMTPPCSLVETPITDEDGEATGESLWVVENKKGEQLRITVEEIHSEQNFDLGQDPGLVKDGVEDHLQELLAEHITTLGDGYTLIRREYPTAIGPVDILCRNSDGETVAVEIKRRGGIDGVEQLTRYLELLNRDELLKPVHGVFAAQEIKPQAKTLAEDRGIKCVTLDYQALRGIESNELTLF
What is the function of this protein?
Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
What are the official names of this protein?
Endonuclease NucS.
What is the protein family that this protein belongs to?
Belongs to the NucS endonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YL112_MIMIV
Sequence: MDITYDDLPVEIWIRILKFMKDSAVNLVLVNTDFFKLIYFKKNKFYELKEFNFGMQKNYVKQRITLINYVVEKGYLDIIVYINNLKSNHNPLIIDNIKILGSISKDTALWYSCKNNNLATTKYFINKGASINSSSLPLKTACIEGHLDTVKYLFSCGIEIINSIYDCIVSACCYGRLNIVIYLSNKISIPGDYINEAFVMACKYGYLDIAKYLFNLDCSITVDALYGACINGHIEVVEYLIGLGVDPRKEKCWAITSACQGGHLNIIEFLLSLGIKPKEINVDAFYHACKTGNLEIAKYLKEIGADTITRRDWALELSARGGYLDVVKYIIELGVSQKSLNKALIDATLFCRVEVVEYLVDSGSDFRQNDDYLFRSIICTRDYVEMAEYFIMKGVNIIVNNNEPIKTVCHNGCIGILKLLIMYGVDYNPIKDQLINIAKSNNQSAIIKYLEDLDTLK
What are the official names of this protein?
Putative ankyrin repeat protein L112.
Protein: GREA_FRATF
Sequence: MANDRVPMTPAGEQALRAELDKLKKIERPAIIEAIAEARDHGDLKENAEYHAARERQGIIEGRIKDIESKLSNAQVIDVTKIQANGMVIFGATVTIMNVDTEEETTYKIVGEDEADIDNQKISVVAPLARALIKKEEGDEITLDTPKGKVTYEIVAVEYK
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: MNHG1_STAAE
Sequence: MIKIILISLALIFVIIGALISALAAIGLLRLEDVYSRAHAAGKASTLGAMSLLFGTFLYFIATQGFVNMQLIVAIIFVLITGPLSSHMIMKAAYNIKTPYTKKTKVDEISEDLKDTKL
What is the function of this protein?
Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.
What are the official names of this protein?
Na(+)/H(+) antiporter subunit G1, Mnh complex subunit G1.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.