PharMolix/UniProtQA huggingface dataset:
Protein: HFQ_CARHZ
Sequence: MSKNQLNLQDAFLNQVRKENVGVTIFLINGFQLKGFVKGFDNFTVILESEGKQHMIYKHAISTIIPQRPVNTYLAKGGNEENTPS
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: PTHP_STAAM
Sequence: MEQNSYVIIDETGIHARPATMLVQTASKFDSDIQLEYNGKKVNLKSIMGVMSLGVGKDAEITIYADGSDESDAIQAISDVLSKEGLTK
What is the function of this protein?
P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes.  Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources.  P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity (By similarity).
What are the official names of this protein?
Phosphocarrier protein HPr, Histidine-containing protein.
What is the protein family that this protein belongs to?
Belongs to the HPr family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOMA_SOLSE
Sequence: MDRVVIVLSVLSVAASSQSILDQRRFSIAVSRVQHIHLLAQKYFSDFESSLQTEDQRQVNKIFLQDFCNSDDIISPIDKHDTQRSSVLKLLSISVRLIESWEFSSRFVTWSTFPRNQISHKLSELKTGIRMLIEANQDGAEVFSDSSTFQLAPYGNFYQSLGGDESLRRNYELLACFKKDMHKVETYLTVAKCRLSPEANCTL
What is the function of this protein?
Growth hormone plays an important role in growth control and is involved in the regulation of several anabolic processes.  Implicated as an osmoregulatory substance important for seawater adaptation.
What are the official names of this protein?
Somatotropin, Growth hormone.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: BBLN_HUMAN
Sequence: MSGPNGDLGMPVEAGAEGEEDGFGEAEYAAINSMLDQINSCLDHLEEKNDHLHARLQELLESNRQTRLEFQQQLGEAPSDASP
What is the function of this protein?
Essential for intermediate filament organization in intestinal cells, interacts with intermediate filament and regulates intestinal lumen morphology.
What are the official names of this protein?
Bublin coiled-coil protein, UPF0184 protein C9orf16.
What is the protein family that this protein belongs to?
Belongs to the UPF0184 (EST00098) family.
Protein: NTRB_SHIFL
Sequence: MATGTQPDAGQILNSLINSILLIDDNLAIHYANPAAQQLLAQSSRKLFGTPLPELLSYFSLNIELMQESLEAGQGFTDNEVTLVIDGRSHILSVTAQRMPDGMILLEMAPMDNQRRLSQEQLQHAQQVAARDLVRGLAHEIKNPLGGLRGAAQLLSKALPDPSLLEYTKVIIEQADRLRNLVDRLLGPQLPGTRVTESIHKVAERVVTLVSMELPDNVRLIRDYDPSLPELAHDPDQIEQVLLNIVRNALQALGPEGGEIILRTRTAFQLTLHGERYRLAARIDVEDNGPGIPPHLQDTLFYPMVSGREGGTGLGLSIARNLIDQHSGKIEFTSWPGHTEFSVYLPIRK
What is the function of this protein?
Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation.  Under conditions of nitrogen limitation, NtrB autophosphorylates and transfers the phosphoryl group to NtrC.  In the presence of nitrogen, acts as a phosphatase that dephosphorylates and inactivates NtrC.
What are the official names of this protein?
Sensory histidine kinase/phosphatase NtrB, Nitrogen regulation protein NR(II), Nitrogen regulator II, NRII.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LDH_STRP3
Sequence: MTATKQHKKVILVGDGAVGSSYAFALVTQNIAQELGIIDIFKEKTQGDAEDLSHALAFTSPKKIYAADYSDCHDADLVVLTAGAPQKPGETRLDLVEKNLRINKEVVTQIVASGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQALAAKIGVDARSVHAYIMGEHGDSEFAVWSHANVAGVGLYDWLQANRDIDEQGLVDLFISVRDAAYSIINKKGATFYGIAVALARITKAILDDENAVLPLSVFQEGQYEGVEDCYIGQPAIVGAYGIVRPVNIPLNDAELQKMQASANQLKAIIDEAFAKEEFASAAKN
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNFD_BUCBP
Sequence: MKYMRHFLDFYHHKNTSEIMLLVFCAAVPGICTEIYYFGFGVLFQILLSVFFSVSFEFLVKRLRKQTVKSLFSDNSAAVTGVLIGISLPSLSPWWLSFFGAFFSIVIAKQIYGGLGNNIFNPAMTGYSILLVSFPILMTNWSFQNSSYFNLFDLNNTFSVIFCTDINHYYSLIDEFQMMYKFITQATPLEQIRTHVLDFNNKIDNIFEFVNYNYYFKNWKWISINISFLIGGIVLLGFNVICWRIPVSILFSLYVFFALDYYFFKKSMYYPIMQLFFGSTMFSVFFIATDPVTTSITKIGRIVFGCIVGFLIWLIRSFGNYPDAIAFSILLSNSIVPLIDHYTQPRVYGYVKKK
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit D, Rnf electron transport complex subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYQ_PSET1
Sequence: MAEIENRPSNFIRTRIDQDLASGKHASTHTRFPPEPNGFLHIGHAKSICLNFGIAKDYNGLCNLRFDDTNPEKEDINYVNSIKEDVQWLGFNWDGEIKYSSNYFDILYDYAVELINKGLAYVCFLTADQAREYRGTLKEPGKNSPYRDTASDENLALFEKMRNGEFKEGECVLRAKIDMASSFMVLRDPIIYRVRFAHHHQTADKWCIYPMYDFTHCISDALEGITHSLCTLEFQDNRRLYDWVLDNISLECHPQQIEFSRLNLEYTIMSKRKLSDLVVNNHVEGWDDPRMPTIAGLRRRGYTPASIREFCLRIGVTKQENMVEMGMLEACIREDLNENAPRAMAVLDPVKIVIENYDADKVETLSVANHPNKEEMGRRDVPFTREIYIEREDFKEEANNKFKRLVLDKEVRLRGAYVIKAQRVEKDENGEITTIYCTYDPETLGKNPSDGRKVKGVIHWVSASEAITAEVRLYDRLFSVPNPAAADEFESTLNPDSLVILTNAKLEPSLANSAAEQGFQFERTGYFSRDSKAKNIVFNQTVGLRDSWSKTQ
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_ALKEH
Sequence: MKSVKKSFQYGNHTVTLETGGVARQADGAVLVNMSDTVVLVTAVGRKEADPGKGFFPLTVNYQERTYAAGKIPGGFFKREGRPSEKETLTCRLIDRPIRPLFPEGFYNEVQVVATVLSMNPEVDADIPALIGASAALSISGIPFDGPIGAARVGYKDGEYLLNPTFEETAASDLDLVVAGTENAVLMVESEANQLPEEAMLGAVLYGHEQMQVAIQAINELTAEAGKPRWDWHPPQGDAALETAIKDLVGDDLAAAYQIPEKQERQNRIGELRQRAVEALGENREEEGGWPEKDVGDAFKGLEKDIVRGRILAGERRIDGRDTRTVRPIDIEVGSLPRTHGSAIFTRGETQAVVVTTLGTGRDAQIIDAIEGERKEQFMLHYNFPPYCVGETGFMGTPKRREIGHGKLAKRGIEAVMPAADDCPYVIRVVSEITESNGSSSMATVCGTSLSLMDAGVPVKAPVAGIAMGLIKEDEQFAVLSDILGDEDHLGDMDFKVAGTESGVTALQMDIKIQGITREIMEQALEQAREGRLHILGEMNNAISGPRSEMSEYAPRLLTIRIDPDKIRDVIGKGGATIRALTEETGTTIDISDDGKVTIASADKAAADEARRRIELLTADVEVGTVYEGKVSKLMDFGAFVNILPGRDGLVHISQISNERVERVGDYLKEGDTVRVKVLEVDRQGRIRLSMKAVQDGE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NFH1_MEDTR
Sequence: MANFLKLKQFLTLVLILLALAAKSSKSTPSPSSTTRVKGIYWIENPLFPPSSIDTSLFTHIFYAFVSPNKFTYKLEEEEEDSTTVATSLTTFTNTFKTKTPPIPTLLSIGGATSNSTLFAFIASDPTARATFINSTIQVARTFGFDGIDFDWEFPTTTKEMNDLGELLFQWRRAISDETASTSRPPLLLTAAVYFAVNFFLSGERRMYPVDSINKNLDWVNVMSYDLRGSGSNVTGAPSGMFDSKSNVSVVSGLFSWIRGGVAPEKIVMGMPLYGKSWKLQDPNVHGIGAPNVGPGPGVDGGMAYFQVVDFNKQMGAKVVYDKETGSVYSYSGSTWIGYDDPFTVSVKVGFAQALKLGGYFFWAAGYDTSDWKVSTASKAWRPES
What is the function of this protein?
Symbiotic enzyme that hydrolytically inactivates Nod factors (NFs) with a C16:2 acyl chain produced by the microsymbiont Sinorhizobium meliloti (PubMed:27383628, PubMed:29367305).  NFs are lipo-chitooligosaccharide signaling molecules produced by nitrogen-fixing rhizobia to initiate nodulation (symbiosis) on the roots of legumes (PubMed:27383628, PubMed:29367305).  Controls NF hydrolysis at the stage of root hair infection (PubMed:29367305).  Involved in the regulation of growth and branching of mature nodules (PubMed:29367305).  Modulates NF levels and signaling to complete transition of infected nodules to functional nitrogen-fixing organs (PubMed:29367305).  Lacks chitinase activity in vitro toward glycol chitin, carboxymethyl-chitin, colloidal chitin, and the chitin oligosaccharides (N-acetylglucosamine) (GlcNAc)6 and (GlcNAc)5 (PubMed:27383628).
What are the official names of this protein?
Nod factor hydrolase protein 1, MtNFH1, Class V chitinase NFH1, Mtchit5.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.
Protein: RIMP_COXBU
Sequence: MSQARTLHRLIAPAVEALGFELVGCELFRRGATTILQVFVDKPGGIGLDECAKVSRQISAVLDVEDPIRGRYTLEVSSPGLERPLYTANHYRRFIGNKAKIRLREPREGQRQFRGMVVAVDNEEQVTLQLDNKILKVSLGEIEKANLIADFEG
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_SHESR
Sequence: MADTTVEKLATEVGKSVERLIEQFSQAGIKKGHTDNVSEAEKQQLLDYLKKQHGGDNAPTKMTLQRKTVSTLSVAGNGGQSKDVKVEVRKTRTFVKRDANDAVLKAEEEAKAKAEAEAKAKAEAEAKAKAEAEVKAKAEAEAKAKAEAEAKAKAKAAAEVKVIKELSPEAEAARVEAERLKAVQAEATKRKQDEEAAKAAEKARLLAEENSKRWAEEERQRLEAERYSDHHITTSKVARAAEDSSDMDEEKRGRRARNKNTAKSKRGGKDARDGREKHMRNRSTAPESMAHGFNKPVAAVNRDVRIGETVTVAELAHLMAVKATEIIKQMMKMGSMVTINQVLDQETAQLVAEEMGHKVVLIRENELEQQVLSERDEEGVVKLEPRAPVVTIMGHVDHGKTSLLDYIRRAKVAAGEAGGITQHIGAYHVETDNGMITFLDTPGHAAFTAMRARGAKATDIVVLVVAADDGVMPQTIEAIQHAKAGNVPLIVAVNKMDKPEADIDRVKSELAQHGVMSEDWGGDNMFAFVSAKTGAGVDDLLEGILLQAEVLELKAVRDGMAAGVVIESQLDKGRGPVATILVQEGTLRQGDIVLCGLEYGKIRAMKDENGRSITEAGPSIPVEILGLSGVPSAGDEATVVRDERKAREVALYRQGKFRDVKLARQQKSKLENMFANMTEGEVKELNIVLKADVQGSLEAITDSLMGLSTDEVKVNIIARGVGALTETDATLAAASNAIMVGFNVRADAQARKTIESESVDLRYYSVIYNLIDEVKAAMTGMLSPEFKQQIIGLAEVRDVFKSPKLGAIAGCMVTEGTIKRSAPIRVLRDNVVIFEGELESLRRFKDDVNEVRNGMECGIGVKNYNDVRVGDQIEVFETVEVARTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHEB_SALRD
Sequence: MIRVLVVDDSLVMRKAISRIFEQADDTTVVDTATNGEAGVEKARRLEPDVVTMDVEMPKMNGIEAVRHIMEASPRPILMLSSLTEKGAEVTMEAMRAGAADFLSKGASSATLRANDVEEKLLGKVRALADSNARLFREDGPSPAETVSSTGSREASSSSSPTSSGTDTATKGSYELAVIGVSTGGPMALQHVIPALPAAFPLPIAIVQHMPAQFTRSLADRLDSLSELAVAEAEDGMLLEPGRVVVAAGDRHLTVERREGALTTCTPAEPAGDSHRPSVNVLFRSAVEACREDVLTLVMTGMGKDGLEGARRIQDDGGTVYVQDEDTSVVYGMPRAVAEAGLADATFPLDDLPDAMQKAAGAPARP
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3A_PYRAE
Sequence: MAEKQKAVAKQEKVAISKRDPWALKKWFSVYAPSYLGGVFLAEVPANEAQKLLMRTLEVSLYDITKDISHLPIKLKFQIHRVEGLKALTRFKGLELTRDYIRSLVRKGTSKVTAITEVKTKDGMVMRIAVLGITTHRIGTAQKSAMRKKMIETLVKKAAELDSGQFLKEILEGTLAADLFIVAKKIAPMRKVEIAKIKVLKYPPEEEQIVVKEAVAEVTSA
What are the official names of this protein?
30S ribosomal protein S3Ae, Ribosomal protein S1e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
Protein: ZN583_HUMAN
Sequence: MSKDLVTFGDVAVNFSQEEWEWLNPAQRNLYRKVMLENYRSLVSLGVSVSKPDVISLLEQGKEPWMVKKEGTRGPCPDWEYVFKNSEFSSKQETYEESSKVVTVGARHLSYSLDYPSLREDCQSEDWYKNQLGSQEVHLSQLIITHKEILPEVQNKEYNKSWQTFHQDTIFDIQQSFPTKEKAHKHEPQKKSYRKKSVEMKHRKVYVEKKLLKCNDCEKVFNQSSSLTLHQRIHTGEKPYACVECGKTFSQSANLAQHKRIHTGEKPYECKECRKAFSQNAHLAQHQRVHTGEKPYQCKECKKAFSQIAHLTQHQRVHTGERPFECIECGKAFSNGSFLAQHQRIHTGEKPYVCNVCGKAFSHRGYLIVHQRIHTGERPYECKECRKAFSQYAHLAQHQRVHTGEKPYECKVCRKAFSQIAYLDQHQRVHTGEKPYECIECGKAFSNSSSLAQHQRSHTGEKPYMCKECRKTFSQNAGLAQHQRIHTGEKPYECNVCGKAFSYSGSLTLHQRIHTGERPYECKDCRKSFRQRAHLAHHERIHTMESFLTLSSPSPSTSNQLPRPVGFIS
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 583, Zinc finger protein L3-5.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RRN10_YEAST
Sequence: MDRNVYEACSNIIKEFGTHVVSADEVLAEKIDNAVPIPFKTREEIDADVEKDRNEGVFEGNIIPDIDLRVVHYYATQLCLNKYPHLINAFDETSLITLGLLIEKWVKDYLTSIQTEQGRQSKVIGKGPCEFISKHIDYRHAPGNI
What is the function of this protein?
Component of the UAF (upstream activation factor) complex which interacts with the upstream element of the RNA polymerase I promoter and forms a stable preinitiation complex.  Together with SPT15/TBP UAF seems to stimulate basal transcription to a fully activated level.
What are the official names of this protein?
RNA polymerase I-specific transcription initiation factor RRN10.
Protein: PCNA_THEAC
Sequence: MIRLNLSVKNLKEITDLLSTIVSEAKFRVDENGMSVTAVDPAHVAMIRLEVPKEAFVEFHTDGQEEIALDIDRLKSVIRLASSSENVGITKDGEKLKFELGTINKSISLLDPSTIVTPKIPNITSEYYAVLKKSDFERGLRAAEDISDSIRFTLSQDGFKAYSHSESEESEMILPKDLITDMSCNTTIKSSYPLEYLLKFIKAISSTDSLKLSFRDDYPLSVEFYLDQNPGAKIKGLFLLAPRMEQ
What is the function of this protein?
Sliding clamp subunit that acts as a moving platform for DNA processing.  Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
What are the official names of this protein?
DNA polymerase sliding clamp, Proliferating cell nuclear antigen homolog, PCNA.
What is the protein family that this protein belongs to?
Belongs to the PCNA family.
Protein: HBP_ECOLX
Sequence: MNRIYSLRYSAVARGFIAVSEFARKCVHKSVRRLCFPVLLLIPVLFSAGSLAGTVNNELGYQLFRDFAENKGMFRPGATNIAIYNKQGEFVGTLDKAAMPDFSAVDSEIGVATLINPQYIASVKHNGGYTNVSFGDGENRYNIVDRNNAPSLDFHAPRLDKLVTEVAPTAVTAQGAVAGAYLDKERYPVFYRLGSGTQYIKDSNGQLTKMGGAYSWLTGGTVGSLSSYQNGEMISTSSGLVFDYKLNGAMPIYGEAGDSGSPLFAFDTVQNKWVLVGVLTAGNGAGGRGNNWAVIPLDFIGQKFNEDNDAPVTFRTSEGGALEWSFNSSTGAGALTQGTTTYAMHGQQGNDLNAGKNLIFQGQNGQINLKDSVSQGAGSLTFRDNYTVTTSNGSTWTGAGIVVDNGVSVNWQVNGVKGDNLHKIGEGTLTVQGTGINEGGLKVGDGKVVLNQQADNKGQVQAFSSVNIASGRPTVVLTDERQVNPDTVSWGYRGGTLDVNGNSLTFHQLKAADYGAVLANNVDKRATITLDYALRADKVALNGWSESGKGTAGNLYKYNNPYTNTTDYFILKQSTYGYFPTDQSSNATWEFVGHSQGDAQKLVADRFNTAGYLFHGQLKGNLNVDNRLPEGVTGALVMDGAADISGTFTQENGRLTLQGHPVIHAYNTQSVADKLAASGDHSVLTQPTSFSQEDWENRSFTFDRLSLKNTDFGLGRNATLNTTIQADNSSVTLGDSRVFIDKNDGQGTAFTLEEGTSVATKDADKSVFNGTVNLDNQSVLNINDIFNGGIQANNSTVNISSDSAVLGNSTLTSTALNLNKGANALASQSFVSDGPVNISDATLSLNSRPDEVSHTLLPVYDYAGSWNLKGDDARLNVGPYSMLSGNINVQDKGTVTLGGEGELSPDLTLQNQMLYSLFNGYRNIWSGSLNAPDATVSMTDTQWSMNGNSTAGNMKLNRTIVGFNGGTSPFTTLTTDNLDAVQSAFVMRTDLNKADKLVINKSATGHDNSIWVNFLKKPSNKDTLDIPLVSAPEATADNLFRASTRVVGFSDVTPILSVRKEDGKKEWVLDGYQVARNDGQGKAAATFMHISYNNFITEVNNLNKRMGDLRDINGEAGTWVRLLNGSGSADGGFTDHYTLLQMGADRKHELGSMDLFTGVMATYTDTDASADLYSGKTKSWGGGFYASGLFRSGAYFDVIAKYIHNENKYDLNFAGAGKQNFRSHSLYAGAEVGYRYHLTDTTFVEPQAELVWGRLQGQTFNWNDSGMDVSMRRNSVNPLVGRTGVVSGKTFSGKDWSLTARAGLHYEFDLTDSADVHLKDAAGEHQINGRKDSRMLYGVGLNARFGDNTRLGLEVERSAFGKYNTDDAINANIRYSF
What is the function of this protein?
Interacts with hemoglobin, degrades it and subsequently binds the released heme.  Could make heme accessible not only for E. coli, but also for B. fragilis during mixed intra-abdominal infections.  Has a role in abscess formation.
What are the official names of this protein?
Hemoglobin-binding protease hbp autotransporter.
What are the subcellular locations of this protein?
[Hemoglobin-binding protease hbp autotransporter]: Periplasm. SUBCELLULAR LOCATION: [Hemoglobin-binding protease hbp]: Secreted. Cell surface. SUBCELLULAR LOCATION: [Hemoglobin-binding protease hbp translocator]: Cell outer membrane; Multi-pass membrane protein. Note=The cleaved C-terminal fragment (autotransporter domain) is localized in the outer membrane.
Protein: RNH2_RHOP5
Sequence: MPHRARDTVLEPPELRARREFPVAWAGAGPQHPGMIRKAPKSDAAPPAKGVIAVAPPSFRRERALLKRGIWPVAGCDEAGRGPLAGPVVAAAVVLDPKRIPKGLDDSKKLTAEKREALFEEICATASFAVAYASPARIERDNILRASLWALARAVQALPEPPKHVFVDGRDKIITPCDCDAVIGGDALVLSIAAASIIAKVARDRLMCRLAEDCPGYGFDHHKGYGVPEHLAALDRLGPTKHHRKLFAPVAAAWDKHAPGERETAAAPPDLFGLSASA
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTU_SALCH
Sequence: MPESKYRQQTIRAPRGTVLTAKSWLTEAPLRMLMNNLDPDVAENPHELVVYGGIGRAARNWECYDAIVDALTRLEADETLLIQSGKPVGVFKTHDNAPRVLIANSNLVPHWATWEHFNELDAKGLAMYGQMTAGSWIYIGSQGIVQGTYETFVEAGRQHYNGTLAGRWVLTAGLGGMGGAQPLAATLAGACSLTIECQQSRIDFRLRTRYVDEQAATLDDALARITRYTREGKAVSVALCANAADILPELVNRGVRPDLVTDQTSAHDPLHGYLPSGWRWEEYQKNAQSDPHGTMQAAKRSMAAHVRAMLAFSKMGVPTFDYGNNIRQMAKEMGVENAFDFPGFVPAYIRPLFCRGIGPFRWVALSGDPQDIYKTDAKVKEIVAEDKHLHHWLDMARERIHFQGLPARICWVGLEWRQKLGLAFNEMVRCGEVSAPIVIGRDHLDSGSVASPNRETEAMRDGSDAVSDWPLLNALLNTASGATWVSLHHGGGVGMGFSQHAGMVIVCDGTDEAAARIRRVLHNDPATGVMRHADAGYDLAVECAVEQGLNLPMVAATQGKG
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUT_ECO5E
Sequence: MMKKIDVKILDPRVGKEFPLPTYATSGSAGLDLRACLDDAVELAPGDTTLVPTGLAIHIADPSLAAMMLPRSGLGHKHGIVLGNLVGLIDSDYQGQLMISVWNRGQDSFTIQPGERIAQMIFVPVVQAEFNLVEDFDATDRGEGGFGHSGRQ
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: YQGF_BACAA
Sequence: MRILGLDVGTKTVGVAISDEMGWTAQGLETIKINEERGQFGFDRISELVKQYDVDKIVVGLPKNMNGTIGPRGEACQQFAENLRELLQLDVVMWDERLSTMAAERLLISADVSRKKRKQVIDKMAAVVILQGFLDSK
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_VIBC1
Sequence: MANSLYQKHIISIPELSREELELIVETAGQLKKEPRPELIKNKVVASCFFEPSTRTRLSFETAIQRIGGDVIGFDNGGNTSLAKKGETLSDSVQVISSYVDAFVMRHPQEGAARLASEFSNGVPVINAGDGANQHPTQTLLDLYTIAETQSRLDNLNVAFVGDLKYGRTVHSLTQALAKFNNIRFFFVAPEALAMPDYLCEELDEAGIQYSLHTDMESVIPELDILYMTRVQKERFDESEYAHIKSAYILTAALLEGARENLKVLHPLPRVDEITTDVDVTPHAYYFQQAENGVYARQALLALVLNETL
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: MDTB_SHIBS
Sequence: MQVLPPSSTGGPSRLFIMRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQSSGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVYSKVNPADPPIMTLAVTSTAMPMTQVEDMVETRVAQKISQISGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPSRAVTLSANDQMQSAEEYRQLIIAYQNGAPIRLGDVATVEQGAENSWLGAWANKEQAIVMNVQRQPGANIISTADSIRQMLPQLTESLPKSVKVTVLSDRTTNIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLIFSLIAVLIPLLFMGDIVGRLFREFAITLAVAILISAVVSLTLTPMMCARMLSQESLRKQNRFSRASEKMFDRIIAAYGRGLAKVLNHPWLTLSVALSTLLLSVLLWVFIPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGVDGTNPSLNSARLQINLKPLDERDDRVQKVIARLQTAVDKVPGVDLFLQPTQDLTIDTQVSRTQYQFTLQATSLDALSTWVPQLMEKLQQLPQLSDVSSDWQDKGLVAYVNVDRDSASRLGISMADVDNALYSAFGQRLISTIYTQANQYRVVLEHNTEITPGLAALDTIRLTSSDGGVVPLSSIAKVEQRFAPLSINHLDQFPVTTISFNVPDNYSLGDAVQAIMDTEKTLNLPVDITTQFQGSTLAFQSALGSTVWLIVAAVVAMYIVLGILYESFIHPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPRDAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQVLTLFTTPVIYLLFDRLALWTKSRFARHEEEA
What are the official names of this protein?
Multidrug resistance protein MdtB, Multidrug transporter MdtB.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RUVB_THESQ
Sequence: MSEFLTPERTVYDSGVQFLRPKSLDEFIGQENVKKKLSLALEAAKMRGEVLDHVLLAGPPGLGKTTLAHIIASELQTNIHVTSGPVLVKQGDMAAILTSLERGDVLFIDEIHRLNKAVEELLYSAIEDFQIDIMIGKGPSAKSIRIDIQPFTLVGATTRSGLLSSPLRSRFGIILELDFYTVKELKEIIKRAASLMDVEIEDSAAEMIAKRSRGTPRIAIRLTKRVRDMLTVVKADRINTDIVLKTMEVLNIDAEGLDEFDRKILKTIIEIYRGGPVGLNALAASLGVEADTLSEVYEPYLLQAGFLARTPRGRVATEKAYKHLKYEVPENRLF
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: RS19_CHLSY
Sequence: MSRSSKKGPYVDIKLLDKIEAMNKANEKRVIRTWSRDSTIFPQMIGHTIAVHDGRRHVPVYITENMVGHKLGEFAPTRFFRGHGGKKADKRGKVK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.