PharMolix/UniProtQA huggingface dataset:
Protein: COXX_STAA2
Sequence: MSKEHTLSQNISRVNFKELQQIIKMGLVQGNLIPAFAGAWLAVVMTNHSFLSSIPQILLMLFGSTLIMGGACALNNYYDQDIDRIMPSKQNRPTVNNRITDQNLLLLSFGMMLVGEICLFLLNIPSGVLGLMGIVGYVSYYSIWSKRHTTWNTVIGSFPGAVPPLIGWVAIEGQISLTAIALFLVVFCWQPIHFYALAIKRKDEYALANIPMLPSVKGFKRTRVSMFIWLIILLPVPLLLINLGVVFVVLATLLNLGWIALGLTTFKKNSDQTKWATQMFIYSLNYLVIFFVLAVIVSLLTLI
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SECF_HALVD
Sequence: MVEFTVPEVDYTRYTNRQLAAVPLAVLAVALLVIGGWYVATGAPVNPGVDFTGGTELRIATDAPQSEVAAAFDSQPESIRSVAADGTYVVTFQSGSATSTELQTQAEDAGFEVRSIDAVSANFGGETQLLALGGLAVAFAGMSVLVFAMFRSFVPSIAVVLSAFSDIVIPVALMNLFGIELSLGTVAALLMLIGYSVDSDILLNNHVLRRSGDFYESTARAMRTGVTMTLTSIAAMIVMTIMATLFGIQLLAAIGTVLVFGLTADLMNTYMLNVTLLRWYKFEGVTR
What is the function of this protein?
Involved in protein export.
What are the official names of this protein?
Protein-export membrane protein SecF.
What is the protein family that this protein belongs to?
Belongs to the SecD/SecF family. SecF subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: 2SSB_BRANA
Sequence: MANKLFLVSATLAFFFLLTNASIYRTVVEFDEDDATNPAGPFRIPKCRKEFQQAQHLKACQQWLHKQAMQSGSGPSWTLDGEFDFEDDMENPQGPQQRPPLLQQCCNELHQEEPLCVCPTLKGASKAVKQQIQQQGQQQGKLQMVSRIYQTATHLPKVCKIPQVSVCPFQKTMPGPSY
What is the function of this protein?
The small, basic, water-soluble napins are one of the two major kinds of storage proteins synthesized in the seed during its maturation.
What are the official names of this protein?
Napin-B, 1.7S seed storage protein.
What is the protein family that this protein belongs to?
Belongs to the 2S seed storage albumins family.
Protein: RL21_NATPD
Sequence: MPSSNGPRQATRNKLKNDARERGTSPPQRSIEEYDDGEKVHLKLDPSVPNGQFHPRFNGRTGTVVGEQGDAFKVEIEDGNVTKTVIAAPAHLRRQQA
What are the official names of this protein?
50S ribosomal protein L21e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL21 family.
Protein: RLMKL_PSEPW
Sequence: MSDRFELYLTCPKGLEGLLAEEAKGLGLDDVREHTSAIRGAADMETAYRLCLWSRLANRVLLVLKRFNMKNADDLYDGVNAVDWADHLAADGTLAVEFSGHGSGIDNTHFGALKVKDAIVDKLRNREGLRPSVEKVDPDVRVHLRLDRGEAILSLDLSGHSLHQRGYRLQQGAAPLKENLAAAVLIRAGWPRIAAEGGALADPMCGVGTFLVEAAMIAADMAPNLKRERWGFSAWLGHVPATWRKVHEEAQARAQAGLAKPPLWIRGYEADPRLIQPGRNNVERAGLSEWVKIYQGEVASFEPRPDQNQKGLVISNPPYGERLGDEASLLYLYQNLGERLRQACMGWEAAVFTGAPELGKRMGIRSHKQYAFWNGALPCKLLLFKIQPDQFVTGERREAQADSGDTHRPLPVASEPARLSEGAQMFANRLQKNLKQLGKWARKEQIDCYRVYDADMPEYALAVDLYQDWVHVQEYAAPRSIDPEKAQARLIDALSAIPQALGVDPQRVVLKRRERQSGTRQYERQATEGRFQEVSEGGVRLLVNLTDYLDTGLFLDHRPMRMRIQREAAGKRFLNLFCYTATASVHAAKGGARSTTSVDLSKTYLDWARRNLSLNGFSERNRLEQGDVMAWLEANRDTYDLIFIDPPTFSNSKRMEGVFDVQRDHVQLLDLAMARLAPGGVLYFSNNFRKFQLDEHLAARYVVEEITAQTLDPDFARNNRIHRAWRLQLR
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPG_ECOL5
Sequence: MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDVWLADESQAERVRAELARFLENPADPRYLAASWQAGHTGSGLHYRRYPFFAALRERAGPVTWVMMIACVVVFIAMQILGDQEVMLWLAWPFDPTLKFEFWRYFTHALMHFSLMHILFNLLWWWYLGGAVEKRLGSGKLIVITLISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLIIFALIWIVAGWFDLFGMSMANGAHIAGLAVGLAMAFVDSLNARKRK
What is the function of this protein?
Rhomboid-type serine protease that catalyzes intramembrane proteolysis.
What are the official names of this protein?
Rhomboid protease GlpG, Intramembrane serine protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PAT_ECOL6
Sequence: MNRLPSSASALACSAHALNLIEKRTLDHEEMKALNREVIEYFKEHVNPGFLEYRKSVTAGGDYGAVEWQAGGLNTLVDTQGQEFIDCLGGFGIFNVGHRNPVVVSAVQNQLAKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGTESVEAALKLAKAYQSPRGKFTFIATSGAFHGKSLGALSATAKSTFRKPFMPLLPGFRHVPFGNIEAMLTALNECKKTGDDVAAVILEPIQGEGGVILPPPGYLTAVRKLCDEFGALMILDEVQTGMGRTGKMFACEHENVQPDILCLAKALGGGVMPIGATIATEEVFSVLFDNPFLHTTTFGGNPLACAAALATINVLLEQNLPAQAEQKGDMLLDGFRQLAREYPDLVQEARGKGMLMAIEFVDNEIGYNFASEMFRQRVLVAGTLNNAKTIRIEPPLTLTIEQCELVIKAARKALAAMRVSVEEA
What is the function of this protein?
Catalyzes the aminotransferase reaction from putrescine to 2-oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline.  This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate (gamma-aminobutyrate or GABA) via 4-aminobutanal.  Also functions as a cadaverine transaminase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
What are the official names of this protein?
Putrescine aminotransferase, PAT, PATase, Cadaverine transaminase, Diamine transaminase, Putrescine transaminase, Putrescine--2-oxoglutaric acid transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. Putrescine aminotransferase subfamily.
Protein: Y2803_MYCA1
Sequence: MTTPQFGSQRSDDDNWDIVSSVGYTALLVAGWRALHAVSPRPLVRDDYAKTFIAASGDPYLTGVLANPGTSEDELAFPRLYGVQTRFFDDFFDAAGAAGIRQAVIIAAGLDSRAYRLEWPPATTVFEVDLAKVLEFKARVLGEQGAVPKARRVEVAADLRADWSRPLEAAGFDVESPSAWSVEGLLPYLTDEAQHALFTRISGLSAPGSRIAIGALGSRLDHDQLHALEESHPGVDVSGNVDFSALTYEPQSDPAEWLAAHGWVVDPVRNTLDLQAGYGMTPPEVDVKIDGFMRSQYITAAR
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase MAV_2803.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: PHOH_ECOLI
Sequence: MVTSCTGHVLDNQRATTRGVFSSGSHLVTLHFQPHPFFSCVTDAVNGARSRFSAFYPKANYGLQGSQPSDVRAHNRAANGACDEYKQLKVLSMGRQKAVIKARREAKRVLRRDSRSHKQREEESVTSLVQMGGVEAIGMARDSRDTSPILARNEAQLHYLKAIESKQLIFATGEAGCGKTWISAAKAAEALIHKDVDRIIVTRPVLQADEDLGFLPGDIAEKFAPYFRPVYDVLVRRLGASFMQYCLRPEIGKVEIAPFAYMRGRTFENAVVILDEAQNVTAAQMKMFLTRLGENVTVIVNGDITQCDLPRGVCSGLSDALERFEEDEMVGIVRFGKEDCVRSALCQRTLHAYS
What are the official names of this protein?
Protein PhoH, Phosphate starvation-inducible protein PsiH.
What is the protein family that this protein belongs to?
Belongs to the PhoH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNFT1_XENLA
Sequence: MKHRPVHERQSSTESKNLKETTQLIMQSSSDHTHHQLGSNDSPSACMSLPVPQLSAEGSCTVGDVTVDLSSQDSQHVARSNSRRVRPSTHGRSPSRHGHTHSHDASGPEDANDDSREQSNSISEVFHLYKWLEKSFPYILIFSAKLVVQHITGISVGIGLLTTFLYANKCIVNQVFLRDKCSKLQCLWVLVFLLFSSFLLYYTFSSQALYYSLVFMNPSLGPLHFFDALWVVGITDFIGKFFFMGLKCIILLVPSFVMSHKSKGYWYMALEELAQCYCTLVSTPVWFRYLIDYGNLDSGAEWHFGILLALLYLILKILIIFGQRKTSSDCLRLFLSQPNYGTTATKRQCSEADGMCAICQAEFTKPIALICQHVFCEECISSWFNKEKTCPLCRTLISNHSHKWKDGATSLQLRIF
What is the function of this protein?
E3 ubiquitin-protein ligase that acts in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway, which targets misfolded proteins that accumulate in the endoplasmic reticulum (ER) for ubiquitination and subsequent proteasome-mediated degradation.  Protects cells from ER stress-induced apoptosis.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNFT1, RING finger and transmembrane domain-containing protein 1.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: EFTU_RHOP5
Sequence: MAKAKFERNKPHCNIGTIGHVDHGKTSLTAAITKVLAETGGATFTAYDQIDKAPEEKARGITISTAHVEYETANRHYAHVDCPGHADYVKNMITGAAQMDGGILVVSAADGPMPQTREHILLARQVGVPALVVFLNKCDMVDDPELLELVEMEVRELLSKYDFPGDDIPIIKGSALAALENKDPKLGHDAILELMKAVDSYIPQPERPIDQPFLMPVEDVFSISGRGTVVTGRVERGIIKVGEEIEIVGLRDTVKTTCTGVEMFRKLLDQGQAGDNIGALLRGTKREEVERGQVLCKPGSVKPHTKFKAEAYILTKEEGGRHTPFFTNYRPQFYFRTTDVTGVVHLPEGTEMVMPGDNIAMEVHLIVPIAMEEKLRFAIREGGRTVGAGVVASIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAA_MYCAV
Sequence: MADDPGSSFTTVWNAVVSELNGEPVADAEPNRTTLVTPLTPQQRAWLNLVRPLTIVEGFALLSVPSSFVQNEIERHLRAPITDALSRRLGQQIQLGVRIAPPPDDVEDALIPSAEPFPDTDADLSARRRTDSRASGERGAVTNTQPGWTNYFTERPHAIDPAVAAGTSLNRRYTFDTFVIGASNRFAHAAVLAIAEAPARAYNPLFIWGESGLGKTHLLHAAGNYAQRFFPGMRVKYVSTEEFTNDFINSLRDDRKVPFKRTIRDVDVLLVDDIQFIEGKEGIQEEFFHTFNTLHNANKQIVISSDRPPKQLATLEDRLRTRFEWGLITDVQPPELETRIAILRKKAQMERLAVPDDVLELIASSIERNIRELEGALIRVTAFASLNKTPIDKSLAEIVLRDLIADASTMQISAATIMAATAEYFDTTVVELRGPGKTRALAQSRQIAMYLCRELTDLSLPKIGQAFGRDHTTLMYGQRKILSEMAERRGGFDHVKELTTRIRQRSKR
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids (By similarity).
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_LIBAS
Sequence: MAKGVVFNGLGRVRKFFGKNPEIIDIPDLIEVQKASYDHFLMMNIAPDERPNEGLQAAFKSVFPITAFSGAAMLEFVSYEFDPPKFDVDDCLWRDLTYAVPLKITLRLIVFDVDEFTGAKSIKDIKEQSIYMGDLPLMTKDGTFVIKGTQRIVVSQLHRSPGIHFDHDKGRASLSGKL
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: RIP1_MYCS2
Sequence: MMFGIGIVLFALAILVSVALHECGHMWVARATGMKVRRYFVGFGPTLWSTRRANRLGSTEYGIKAIPLGGFCDIAGMTSVDEIAPEDRPYAMYKQKVWKRVAVLFAGPAMNFVIGLVLIYGIAIVWGLPNLHQPTTAIVGETGCVAPQITLEEMGECTGPGPAALAGIQAGDEIVKVGDTEVKDFAGMAAAVRKLDGPTRIEFKRDGRVMDTVVDVTPTQRFTSADASAPSTVGAIGVSAVPVQPPAQYNPITAVPATFAFTGDLAVELGKSLAKIPTKIGALVEAIGGGERDKETPISVVGASIIGGETVDAGLWVAFWFFLAQLNFVLGAINLVPLLPFDGGHIAVATYEKIRNMIRSARGMVAAGPVNYLKLMPATYVVLAVVAGYMLLTVTADLVNPLSIFQ
What is the function of this protein?
Regulated intramembrane proteolysis (RIP) occurs when an extracytoplasmic signal (possibly oxidative stress) triggers a concerted proteolytic cascade to transmit information and elicit cellular responses.  The membrane-spanning regulatory substrate protein (includes anti-sigma factors RskA, RslA, RsmA, and PbpB) is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, this entry), while cytoplasmic proteases finish degrading the regulatory protein, liberating the effector protein (ECF sigma factors SigK, SigL and SigM).
What are the official names of this protein?
Zinc metalloprotease Rip1, Regulator of sigma KLM proteases, S2P endopeptidase, Site-2-type intramembrane protease, site-2 protease Rip1, S2P protease Rip1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M50B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UGPC_BURTA
Sequence: MAALSLKGVRKSYDGAQYVLHGIDVDIADGEFVVLVGPSGCGKSTLLRMIAGLETVTEGEIAIGGRVVNTLEPKDRDIAMVFQNYALYPHMTVAQNMGYGLKIRGVERALIDARVQAAAQILELGPLLARRPRELSGGQRQRVAMGRAIVREPSVFLFDEPLSNLDAKLRVQMRLEIQRLHARLATTSVYVTHDQIEAMTLAQRVIVMNRGYAEQIGAPVDVYEKPATTFVASFIGSPAMNLLHGRLSEDGAAFDIADGPRLPVAGAAGAGREIAPGREWILGVRPEHMTPLPGAALATLAVDSCELLGADNLAHGRWGVHDVAVRLPHAMRPARGETLPVALPAQHLHFFDPATGKRAG
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
sn-glycerol-3-phosphate import ATP-binding protein UgpC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. sn-glycerol-3-phosphate importer (TC 3.A.1.1.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NCAP_SBVBH
Sequence: MSSQFIFEDVPQRNAATFNPEVGYVAFIGKYGQQLNFGVARVFFLNQKKAKMVLHKTAQPSVDLTFGGVKFTVVNNHFPQYVSNPVPDNAITLHRMSGYLARWIADTCKASVLKLAEASAQIVMPLAEVKGCTWADGYTMYLGFAPGAEMFLDAFDFYPLVIEMHRVLKDNMDVNFMKKVLRQRYGTMTAEEWMTQKITEIKAAFNSVGQLAWAKSGFSPAARTFLQQFGINI
What is the function of this protein?
Encapsidates the genome, protecting it from nucleases.  The encapsidated genomic RNA is termed the nucleocapsid (NC) (By similarity).
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the orthobunyavirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Note=Internal protein of virus particle.
Protein: LEPA_SALPC
Sequence: MKNIRNFSIIAHIDHGKSTLSDRIIQICGGLSDREMEAQVLDSMDLERERGITIKAQSVTLDFKASDGETYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAGQGVEAQTLANCYTAMEMDLEVVPVLNKIDLPAADPERVAEEIEDIVGIDATDAVRCSAKTGVGVTDVLERLVRDIPPPQGDPDGPLQALIIDSWFDNYLGVVSLVRIKNGTMRKGDKIKVMSTGQTYNADRLGIFTPKQVDRSELKCGEVGWLVCAIKDILGAPVGDTLTSARNPAEKALPGFKKVKPQVYAGLFPVSSDDYESFRDALGKLSLNDASLFYEPESSSALGFGFRCGFLGLLHMEIIQERLEREYDLDLITTAPTVVYEVETTAKETIYVDSPSKLPPLNNIYELREPIAECHMLLPQAYLGNVITLCIEKRGVQTNMVYHGNQVALTYEIPMAEVVLDFFDRLKSTSRGYASLDYNFKRFQASDMVRVDVLINNERVDALALITHRDNSQSRGRELVEKMKDLIPRQQFDIAIQAAIGTHIIARSTVKQLRKNVLAKCYGGDISRKKKLLQKQKEGKKRMKQIGNVELPQEAFLAILHVGKDNK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TYW31_PYRFU
Sequence: MQFSENFERAKKEALISLEIALRKGEVDEDIIPLLKKINSLDNYFTTSSCSGRISVMEMPHFGDKVNAKWLGKWHREVSLDEVLGAIKKHRSGQLWFLVRSPILHVGAKTLEDAIRLVNLAVSCGFKYSNIKSISNKKLIVEIRSTERMDVLLGENGRILVGEEYLRKIVEIANAQVRRFKEKLKRLESNIDALNR
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway.  Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72.
What are the official names of this protein?
tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase 1, tRNA wyosine derivatives biosynthesis protein Taw3 1.
What is the protein family that this protein belongs to?
Belongs to the TYW3 family.
Protein: PUR5_CLOBK
Sequence: MVSYKEAGVNIEEGYKSVDLIKKHASKTFTKGVLNNLGSFAGMFELPKYKNPVLVSGTDGVGTKLDIAFRMKKYNTVGIDCVAMCVNDILCHGAKPLFFLDYIACGKLESEIAAQLVEGVSNGCIQSECALIGGETAEMPGFYRDGEYDIAGFAVGIAEKDEIIDGSKIEDGDILIGIASSGPHSNGYSLIRKLVEDLHKDFEGNKIGNTLLTPTKIYVKPVMKLLEKYNIKGMAHVTGGGFYENIPRMFKEDFTAVINKKSYPLPNIFSHLMSLGIEEDHMYNTFNMGIGFVLCVNEKDGENIIKDLIEMGEKGYKIGYVKKGDKSVELI
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_SYNC1
Sequence: MTKGILGKKLGMTQVFAVDGKCIPVTVVEAGPCVVLQKKTEEKDGYNALQLGFGAKKTQSVNKPAMGHFKKSGKGAFEFLREVECENIDDHAVGDEITCDGFFATGDVIDVTGTSKGKGFQGVIKRWNFAGGRASHGSMFHRRPGGIGASAWPSRVFKGKKMAGQMGNKRVTTQGLEVVDVRPEKSLVLIKGAVPGPVNGLLLIRKSRKV
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: DNAA_STRPJ
Sequence: MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFLPRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYSPKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLGKTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLIDDIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQTITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVKKIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVLARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKKKIK
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSMA4_STAAW
Sequence: MAIVGTIIKIIKAIIDIFAK
What is the function of this protein?
Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection.  Stimulates the secretion of the chemotactic factor interleukin-8 (IL-8).  The ensuing activation process triggers an inflammatory response in the host, thus contributing greatly to virulence.  Also possesses hemolytic activity, which may contribute to the development of disease.
What are the official names of this protein?
Phenol-soluble modulin alpha 4 peptide.
What is the protein family that this protein belongs to?
Belongs to the phenol-soluble modulin alpha peptides family.
Protein: MRAY_MICAN
Sequence: MNANIFSAPIFKKPTGTHLLILLTGLLFLLVVFFQSTNSLLIPLMATTLISAGLGCQVVPMLRRLKMGQIMREDGPQAHLKKAGTPTMGGSFFVPVALIFALIWSKFTPNVVAVALLTFVYMGIGWLDDWQILRYKSNKGLSPQMKLILQITGAVLFCLWMLVNQVSTDITLWGRLVIPLGFFFWILAGFVLVAESNATNLTDGVDGLAGGTGAIAFLGLGIIIAPSHPDLAIFCTCFAGACLGFIFHNRNPAKVFMGDTGSLALGGALAAVGLIAGHLWGLFLISGLFFLESLSVIAQVIYYKATKGPDGKGKRLLKMAPFHHHLELSGWTETKIVGAFYLVNALLVVLAIWSS
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ISPH_CHLT2
Sequence: MRKIILCSPRGFCAGVIRAIQTVEVALEKWGRPIYVKHEIVHNRHVVDKLREKGAIFIEDLQEVPRNSRVIFSAHGVPPSLREEATERGLIAIDATCGLVTKVHSAVKMYAKKGYHIILIGKRKHVEIIGIRGEAPDQITVVENIAEVEALPFSAQDPLFYVTQTTLSMDDAADIVAALKARYPRIFTLPSSSICYATQNRQGALRNILPQVDFVYVIGDRQSSNSNRLREVAERRGVTARLVNHPDEVTEEILQYSGNIGITAGASTPEDVVQACLMKLQELIPDLSIEMDLFVEEDTVFQLPKEL
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: OR2L3_HUMAN
Sequence: MENYNQTSTDFILLGFFPPSRIGLFLFILIVFIFLMALIGNLSMILLIFLDTHLHTPMYFLLSQLSLIDLNYISTIVPKMASDFLSGNKSISFTGCGIQSFFFSALGGAEALLLASMAYDRYIAICFPLHYPIRMSKRMCVLMITGSWIIGSINACAHTVYVLHIPYCQSRAINHFFCDVPAMVTLACMDTWVYEGTVFLSTTIFLVFPFIAISCSYGRVLLAVYHMKSAEGRKKAYLTCSTHLTVVTFYYAPFVYTYLRPRSLRSPTEDKVLAVFYTTLTPMLNPIIYSLRNKEVMGALTRVSQRICSGKM
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 2L3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HEM1_BORA1
Sequence: MSVAVLAFGLNHTSAPVSVRERVSMPVDLVKPALAGLRSAFGGAVREAAILSTCNRTEVYCAADAAVAEQLPIWLADHHCMEAGSLHPHLYRLHQNDAVRHAFRVASGLDSMVLGEPQILGQMKDAVRAAEEAGSLGTLLHQLFQRTFAVAKEVRSQTEIGAHSVSMAAAAVRLAERVFGDLGQARTLFIGAGEMIELCATHFAAQHPRSMVVANRTAERAESLAGRFSAGTMKLADLTERLAEFDVVVSCTASSLPILGLGMVERATRQRRHRPMVMIDLAVPRDIEPEVGRLDDVYLYSVDDLGRLVQSGTDARRAAVVQAEAIIETRVQGFMHWMQSREVVPVIRGLHQAAEDVQAAELERARRLLARGESPEAVLEQLAHGLTQKYLHGPLAALNRSAGDERKQLLAWMPRLFPGRDSRR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: ARND_PHOLL
Sequence: MKQIGLRVDVDTYRGTVEGVPKLLKILAKHQIQASFFFSVGPDNMGRHLWRLLRPKFLWKMLRSNAASLYGLDILLAGTAWPGKKIAKDLGYLMKQTLNAGHEVGLHAWDHQRWQAKVGRWSEAQLTEQVKLGVDALVQAIGQRVTCSAVAGWRADERVLAVKQQFGFDYNSDCRGTHPFRPILPDGTLGTVQIPVTLPTYDEVIGIQVKDEDFNQFILDKMKNSQGVPVYTIHTEVEGMSKSTEFATLLEMVHQENIQFCALSHLLPENIQRLPVGRIVRSEFPGREGWLGCQQEA
What is the function of this protein?
Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
Protein: PANB_LEPBP
Sequence: MKNIILQYKKKYDAGEPISVVTCYDYTFATLFNRTDVDCLLVGDSLGMVIQGNQSTLPVTLDEIIYHTKAVCKGAPDKTIIADLPFLSYQTSIEEGIRSAGRVLKETNASCVKLEGDSEFIIELTKRMTESGIPVFAHLGLTPQSVHTLGGHRVQGKTEAARNKMIRKSRELAEAGAFALLLEMVPESLGKEITESIRIPTIGIGAGKYTSGQVLVMQDLLGLNEDFHPKFLKKFGNLSGAVKEAVNAYHKEVTKREYPSEAHVFLDT
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.