PharMolix/UniProtQA huggingface dataset:
Protein: CRR41_ARATH
Sequence: MSSVFGSVHILAMIAIQLLLTHSVSSLNLTNAYLHHKCSNTQGKYKQGSAFEKNLNLVLSTITSIGNFRDGFRYTEEGEDPNNVFVMFQCRGDSYWSKCPPCISTAVSGLRRRCPRNKGAIIWYDQCLLKISSVASFNKIDYENDFYLSNPNNMSDRGLFNKETSALLEKLAYKASDRNNLDGKQLVLYAAGEKRIGTKKVYAMVQCTKDLIFTKCFECLEGILRKFPQCCDGKRGGRVFGTSCNFRYELYPFLRNYSNSTMRAPY
What are the official names of this protein?
Cysteine-rich repeat secretory protein 41.
What is the protein family that this protein belongs to?
Belongs to the cysteine-rich repeat secretory protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: PURA_POLSJ
Sequence: MTYKPTVAAGRNVVVVGTQWGDEGKGKLVDWLTEMSQGVVRFQGGHNAGHTLVINGIKTALHLIPSGIMRPGVKCYIGNGVVLSAAKLFEEIEGLEKAGVEVRSRLRISEACPLILPFHAALDIAREAYREKGGTARIGTTGRGIGPAYEDKIARRALRVQDLKYPERFAAKLRELLDLHNFVLTGYLHAPAIDFDTVYAEAMRHAELLKPMMADVSRELNDANREGANLLFEGAQGTLLDVDHGTYPYVTSSNCVAGNAAAGAGVGPGMLHYILGITKAYCTRVGGGPFPTELDWETPDTVGYHLSTVGAEKGVTTGRSRRCGWFDAALLKRSAQVNGLSGLCITKLDVLDGIAELKLCTGYELDGHITDILPMGAEDIERCKPIYETLPGWSQSTVGVTQYDQLPAAAQKYLHRIEEVTGVPIDMISTSPDRDHTILLRNPYAA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURR_SALPA
Sequence: MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWTAIKELHYSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLEKQRAYLSMMAQKRVDGLLVMCSEYPEPLLSMLEEYRHIPMVVMDWGEAKADFTDTVIDNAFAGGYMAGRYLVERGHRDIGVIPGPLERNTGAGRLAGFMKAMEEALINVPDNWIVQGDFEPESGYHAMQQILSQSHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSVIGYDNVRNARYFTPALTTIHQPKDSLGETAFNMLLDRIVNKREESQSIEVHPRLVERRSVADGPFRDYRR
What is the function of this protein?
Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression.  PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.
What are the official names of this protein?
HTH-type transcriptional repressor PurR, Pur regulon repressor, Purine nucleotide synthesis repressor.
Protein: ATPL_AZOPC
Sequence: MLLSILLQVATGTGLAKLGEALGAGLAVIGAGLGIGKIGESAMEGIARQPEAAGDIRMNMIIAAALVEGVSLFAVVVCGFLL
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUOC_CUPMC
Sequence: MANLDTLKAALEKVLGKRVQNLIEATGELTLIVKAADYLEVARLLRDDPSLRFEQLLDLCGVDYSDYAEGAWDGLRFAAVSQLLSVTHNWRLRLRVFAPDDDFPVLPSVINVWNSVNWFEREAFDFYGIVFEGHPDLRRILTDYGFVGHPFRKDFPVSGYVEMRYDPEQKRVIYQPVTIEPREVTPRVIREENYGGTQH
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GLYA_CALS8
Sequence: MQMYFYNLVKDTDPEIAEAIKNELKRQQNKIELIASENFVSIAVMAAMGSPLTNKYAEGYPNKRYYGGCEYIDVVESIAIERAKKLFGAEHANVQPHSGAQANMAVYFAVLNPGDTILGMNLSHGGHLTHGSPVNFSGKLYNIVSYGVDPETETIDYDEVLRLAKEHRPKLILAGASAYPRIIDFKKFREIADEVGAYLMVDMAHIAGLVAAGLHPSPVEYADFVTTTTHKTLRGPRGGLILCKEKYAKLIDKSIFPGIQGGPLEHVIAAKAVALKEAMTEEFRNYQIQILKNAKALSERLIERGFRLVSGGTDNHLMLVDLRNKGITGKDAEKRLDSLNITCNKNAIPFDTQSPMVTSGIRLGTPAVTTRGFKEEDMIEVADIIHDALTNSDTDDNILQRVKALCEKYPLYSEFRE
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 6PGL_BORBU
Sequence: MEFLYSDEENYLKDRFFDFFNMNVDKDKYTSIGICGGRSIVNFLSVFLKQNFSFRRSHFFLVDERCVPLNDENSNYNLLNKNFFSKMVDKNLISISKFHAFVYSEIDEATAIHDYNIEFNSRFNIFDFIIVSVGEDGHIASLFPSRKLLFSDVEGYQYEYNSPKFPSKRISLTPKSLFGSKAVVLLFMGVDKKCALENFLASNSSINECPARLLKEHPNLLVLTNIKRDESYAGS
What is the function of this protein?
Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
What are the official names of this protein?
6-phosphogluconolactonase, 6PGL.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
Protein: RL6_JANSC
Sequence: MSRIGKRPVELPGGVEASVSGQTVEVKGPKGTRSFKATDDVTVSVDGNVISVEPRGKSKRARQQWGMSRTMVQNLVTGVTDGFKKELEITGVGYRAQMQGNVLKLSLGYSHDVDFTVPEGVTVTCPKNTEVIIEGNDQQLVGQVAANIREWRAPEPYKGKGIRYKGEYIFRKEGKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: CYSG_NITMU
Sequence: MNFLPIFLDIHDRNCVVAGGGEVAARKVAMLLRAGAHVTVVAPRLCSELLEQLNEQSREGKLAYRAETFQDEHLADAVLVIAATDDFAVNQRISEAAKRLRIPVNVVDNPGLCSFIMPSIVDRTPVVVAVSSGGASPVLTRLLRARLETMIPMAYGRLAAYAGEFRDRVKHRFSQPAQRRRFWERVLQGPFAEMVFAGKDQAAKAWLERELENETEEPVKGEVYLVGAGPGDPELLTFRAMRLMQQADVVVYDRLVSPEILDMLRRDTPRIYAGKERNRHTMPQESINDLLVRLAKEGKRVLRLKGGDPFIFGRGGEEIETLAGHGIPFEVVPGITAANGAASYAGIPLTHRDYAQSCIFVTGHLKDGSVDLDWPMLARPKQTIVVYMGLLGLTVLCKQLIAHGLPNNTPAAIVQQGTTRKQRVLAATLETLPELTAAAHLVPPTLVIVGEVVNLHRKLAWFQPEGNLPGAE
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: RSB1_YEAST
Sequence: MSNATNNTLGSLLPQLEAAANSNSLYGGMVPNLRFNITMIVIWGILLTIHVVQLLMRQYWFSIAFICTGILEVLGFIGRTWSHSNVADMDAFLLNMICLTIAPVFTMGGIYYQLAKLIEVYGHRFSLLPSPMAYSFIFICSDIVSLVVQAVGGGLCGVAVTDGTSTTTGNHVFIAGLAIQVASMAIFLMLWFHFLFRIYISVRWEHINSRPISLSLLKISQTEVDYLYREKFHFLRLEPKRWVFHYFNLAITVAVLTIFTRCCYRLAELVVGWDGYLITHEWYFIILDALMMAIATVTLTIFHPGFAFKGRSTSIPITPGHVDPETLPHTDDVEDILDTSDSKQFDIEKEEFQASMKYPISTFKQFMSKIANLFSSKKKAKL
What is the function of this protein?
Catalyzes the ATP-dependent translocation of sphingoid long-chain bases (LCBs) from the cytoplasmic site toward the extracytoplasmic side of the membrane (flip-flop).  Involved in the establishment of the functional lipid asymmetry of the plasma membrane.  Regulates intracellular levels of LCBs, sphingolipid precursors that are growth inhibitory at increased levels.
What are the official names of this protein?
Sphingoid long-chain base transporter RSB1.
What is the protein family that this protein belongs to?
Belongs to the lipid-translocating exporter (LTE) (TC 9.A.26.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GCR_RABIT
Sequence: MDSKESLSPPGREEVPSSVLRPAERGNVMDLYKTLRGGAPVRVPASSPSLAPAAQPDSKQQRLAVDFPKGSASNAQQPDLSRAVSLSMGLYMGETETKVMGSDLAFPQQGQTSLSSGETDFRLLEESIASLNRSASGADNPRSTAPAAGSAAPTEGFPKTHSDLASERQNPKGQTGGSAGSAKLHPTDQSTFDILQDLEFSGSPSKDRSESPWRSDLLMDENCLLSPLAGEDDPFLLEGNSSEDCKPLILPDTKPKIKDNGDLILSNSNNVPLPQVKTEKEDFIELCTPGVIKQEKLGPVYCQASFSGANIIGNKISAISVHGVSTSGGQMYHYDMNAQQQEQKPLFNVIPPIPVGSENWNRCQGSGDDNLTSLGTMNFPGRSVFSNGYSSPGMRPDVSSPPSNSTTAAGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVKGQHNYLCAGRNDCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKKKIKGIQQTSTGVSQETSENPSNRTVVPAALPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYKQSSGNMLCFAPDLVINEQRMTLPYMYDQCKHMLFVSSELKRLQVSYEEYLCMKTLLLLSTVPKEGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLHYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK
What is the function of this protein?
Receptor for glucocorticoids (GC).  Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors.  Affects inflammatory responses, cellular proliferation and differentiation in target tissues.  Involved in chromatin remodeling.  Plays a role in rapid mRNA degradation by binding to the 5' UTR of target mRNAs and interacting with PNRC2 in a ligand-dependent manner which recruits the RNA helicase UPF1 and the mRNA-decapping enzyme DCP1A, leading to RNA decay.  Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth.  Mediates glucocorticoid-induced apoptosis.  Promotes accurate chromosome segregation during mitosis.  May act as a tumor suppressor.  May play a negative role in adipogenesis through the regulation of lipolytic and antilipogenic gene expression.
What are the official names of this protein?
Glucocorticoid receptor, GR, Nuclear receptor subfamily 3 group C member 1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=After ligand activation, translocates from the cytoplasm to the nucleus (By similarity). In the presence of NR1D1 shows a time- dependent subcellular localization, localizing to the cytoplasm at ZT8 and to the nucleus at ZT20 (By similarity). Lacks this diurnal pattern of localization in the absence of NR1D1, localizing to both nucleus and the cytoplasm at ZT8 and ZT20 (By similarity).
Protein: SELD_CARHZ
Sequence: MEAVKLTQLVSCAGUAAKMSPETLAQVLRYLPEINDPNALVGTNTADDAAVYRISDEQAIVLTVDYFTPVVDDPYYFGVIAAANSLSDIYAMGAKPLFALNVVGFPKKLPPEILATILKGGADKAREAGIPVLGGHTVDDAEPKYGMVVCGLVHPDKIVKNHPPHPGDSLILTKPLGIGVLTTGMKRGIVPENTAKKVMEVMETLNDKAAEVMVEVGVSAATDITGFGLLGHLKEMLQEEFGAEIYLTKIPAIEGAWEFAGMRVFPGGAKNNLNYLLPHLDFAGEFAEEEKLFLADPQTSGGLLMAVSQEKKEELVKKLQQKGVLAAEIGIITGNKGKIVVKR
What is the function of this protein?
Synthesizes selenophosphate from selenide and ATP.
What are the official names of this protein?
Selenide, water dikinase, Selenium donor protein, Selenophosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the selenophosphate synthase 1 family. Class I subfamily.
Protein: GLYA1_VIBVY
Sequence: MLKRDMNIADYDAELFAAIQEETLRQEEHIELIASENYTSPRVMEAQGSQLTNKYAEGYPGKRYYGGCEYVDKAEALAIDRACQLFGCEYANVQPHSGSQANSAVYMALLNPGDTVLGMSLAHGGHLTHGSPVNFSGKHYNVIPYGIDEAGQINYDEMETLALEHKPKMIIGGFSAYSQIVDWKRMREIADKVDAYLFVDMAHVAGLIAAGEYPTPVPHAHVVTTTTHKTLAGPRGGLILSNAGEDMYKKLNSAVFPGGQGGPLMHVIAGKAVAFKEAMEPEFKAYQARVVKNAKAMVAQFQERGYKIVSNGTENHLFLVDLIDKDITGKDADAALGAANITVNKNSVPNDPRSPFVTSGIRVGTPAITRRGFTEADAKELANWMCDVLDNIGNEAVIEATKQKVLEICKRLPVYA
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase 1, SHMT 1, Serine methylase 1.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPF_AGRRK
Sequence: MSNTVEFARMNGLGNKILVVDMRGRKDVVTAAAAIALNADPATEFDQIMAIHDPKAEGTDAWIDILNSDGTKAQACGNGTRCVVQALAAETGKKVFTFQTVAGILNAVEHEDGTISVDMGRPVFDWDKIPLAEEFADTRRIELQIGPIDNPVLHSPSVMSMGNPHAIFWVDKDPMSYDLARFGPLLENHPMFPERANITLAQVLSPTLLRTRTWERGAGLTLACGSAACSAAVSAARTGRTGRKVTIDVASAPASGQLTIEWRENDDHVVMTGPAEWEWSGVVDPVTGSFTRAQEQGAQAR
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AGUA_SELRU
Sequence: MMIKDSTPKADGFYMPAEFSPHAGTFLIWPVRPGSWTNAGADVQPVFVELIREISAVEELYLLVDEAHRPQAENMLKDLPQQHIHYLAIPTDDAWARDMGPTYVIDGQGRRRGINWRFNAWGGDFDGLYPDYGQDDAAAEKMCAALGDELYDAGDFVLEGGSIHVDGEGTVVVTEACLLSQGRNPDLSKEQIEAMLLKYLGAEKVIWLPRGIHNDETNEHVDNVFAFVRPGEVLLAWTDDKDDPQYELSQADLEVLESATDARGRKFVIHKLPIPQEPVCITAEEADSFTFEEGEDRREPGERLAASYVNFYLCNGKVILPQFGDEMDIEAQRILGKCFPERKVVPLPAKAVIVGGGNFHCLTQQIPAIER
What are the official names of this protein?
Putative agmatine deiminase, Agmatine iminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the agmatine deiminase family.
Protein: KRAF1_CAEBR
Sequence: MSRINLKKSSAATTPTSPHCPSPRLISLPRCASSSIDRKDQGSPMASPSTPLYPKHSDSLHSLSGHDHSGVGTSDKEPPKFKYKMIMVHLPFDQHSRVEVRPGETARDAISKLLKKRNITPQLCQVNTSPDSKTEAIDLSKTMEEIALHLPDNELWVHSEYLNTVSSIKHAIVRRTFIPPKSCDVCNNPIWMMGFRCEFCQFKFHQRCSSFAPLYCDLLQSVPKNEDLVKQLVGIASENDGPDRSVAEIVLAGLAPTYGQSPAATPDSSHPDLTSIKRTGGVKRHPLAVSPQAETAQLSPAGPYPRDRSSSAPNINAINDEATVQHNQRILDALEAKRLEEESKDKTGSLLSTQARRPHCYSGHILSGSRMNRLHPLVDCTPLGSNSPSSTCSSPPGGLMGPTLLGQSSSVSGSTTSSLVAAHLHTLPLTPPQSAPPQKISPGFFRNRSRSPGERIEAQRPRPPQKPQHEDWEILPNEFVIHYKVGSGSFGTVYRGEFFGTVAIKKLNVVDPTPSQMAAFKNEVAVLKKTRHLNVLLFMGWVREPEIAIITQWCEGSSLYRHIHVQEPRVEFEMSAVIDILKQVSLGMNYLHSKNIIHRDLKTNNIFLMDDMSTVKIGDFGLATVKTKWTVNGGQQQQQPTGSILWMAPEVIRMQDDNPYTPQSDVYSFGVCMYEILSSHLPYSNINNRDQILFMVGRGYLKPDRSKIRTDTPKSLMKLYDNCIMFDRNERPVFGEVLERLRDIILPKLTRSQSAPNVLHYDSQYSVMDAVMRSQMVSSSYIPPSTAKTPQSAAAAAAANKKAYYNVYGLI
What is the function of this protein?
Protein kinase that participates in the induction of vulva and has a role in fertility and viability.  Acts downstream of the Ras protein let-60.  Required for progression of developing oocytes through the pachytene stage.  Positively regulates lifespan upstream of mek-2 and mpk-1.
What are the official names of this protein?
Raf homolog serine/threonine-protein kinase, Abnormal cell lineage protein 45.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.
Protein: RECA_BORPD
Sequence: MNDKSSKAAASEKAKALAAALSQIEKQFGKGSIMRYGDNEVEHDIQVVSTGSLGLDIALGVGGLPRGRVIEIYGPESSGKTTLTLQVIAEMQKIGGTCAFVDAEHALDVQYAAKLGVNLTDLLISQPDTGEQALEITDALVRSGSVDLIVIDSVAALVPKAEIEGEMGDSLPGLQARLMSQALRKLTATIKRTNCMVIFINQIRMKIGVMFGNPETTTGGNALKFYSSVRLDIRRIGSIKKGEEVVGNETRVKVVKNKVSPPFKQAEFDIMYGAGISREGEIIDLGVQAGVVDKSGAWYSYSGTRIGQGKDNVREYLKEHPELAVEIENKVRENQGIVSRAATFPASEAEAEDDGQA
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPX_SALRD
Sequence: MNTFRTTALMAVMIVLFALIGQALGGTGGMLLAFLIAVGMNGVSYWYSSSIVLRMYGAEEVSRAEAPELHDLVDRLRRRADLPMPKVCIIPQDQPNAFATGRNPDNAVVAVTKGIMDVLDRDELAGVIAHELAHIKNRDMLTSTVAATLAGAITMLSRFALFFGGRDNNFLVSLLMMILAPMAAMLIQSAISRSREYAADREGAEIAKNPLGLASALRSMERAAEHRPMPANQTTSHMFIVNPFSGGLSGIKRLFSTHPPTEERIARLEEMAGRAQ
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YPIA_BACSU
Sequence: MNTLIQEAIKLVEAGETEKGLNTLSKAEKQLHDEDKAIAAQLYYEWGDVEKAISLISDLHDLYPNETELTNFYAELLIDIDEEEKALAVLETIPETDPSYPESLLLMADLYQMQGLFEVSEQKLFQAKSILDNEPVIDFALGELYFAQGAYAKAVQYFKTTAEEQSEIGGVNVHQRLAESLSASGEFEDAIPWYEKAVDENPDPNTIFGYGFTALQAGLVKTAIKQLSDLKELDPSYTSLYMPLSKSYEAEGMYEEALKTAKEGIRYDEYNKELFLYAAKMALKIGKSEEGKKLLQEALALDPGFVEALHTLLAVYHKEEDYDQIIDLIQEVRSYGEEDPKYNWYLASAYTELEQYEEAKQSFEAAYLHYREDRDFLYEYASFLLEEGLQKEALPLLKKVLEMDGANEELEETILRIEDEFSR
What are the official names of this protein?
TPR repeat-containing protein YpiA.
Protein: KEFB_ECODH
Sequence: MEGSDFLLAGVLFLFAAVAAVPLASRLGIGAVLGYLLAGIAIGPWGLGFISDVDEILHFSELGVVFLMFIIGLELNPSKLWQLRRSIFGVGAAQVLLSAALLAGLLMLTDFAWQAAVVGGIGLAMSSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAVIPALALVPLLAGSADEHFDWMKVGMKVLAFVGMLIGGRYLLRPVFRFIAASGVREVFTAATLLLVLGSALFMDALGLSMALGTFIAGVLLAESEYRHELETAIDPFKGLLLGLFFISVGMSLNLGVLYTHLLWVVISVVVLVAVKILVLYLLARLYGVRSSERMQFAGVLSQGGEFAFVLFSTASSQRLFQGDQMALLLVTVTLSMMTTPLLMKLVDKWLSRQFNGPEEEDEKPWVNDDKPQVIVVGFGRFGQVIGRLLMANKMRITVLERDISAVNLMRKYGYKVYYGDATQVDLLRSAGAEAAESIVITCNEPEDTMKLVEICQQHFPHLHILARARGRVEAHELLQAGVTQFSRETFSSALELGRKTLVTLGMHPHQAQRAQLHFRRLDMRMLRELIPMHADTVQISRAREARRELEEIFQREMQQERRQLDGWDEFE
What is the function of this protein?
Pore-forming subunit of a potassium efflux system that confers protection against electrophiles.  Catalyzes K(+)/H(+) antiport.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system protein KefB, K(+)/H(+) antiporter.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RRF_SHEON
Sequence: MIADIKKDAQERMGKCVDATKNQMAKVRTGRAHPSLLDSIQVSYYGTMTPLNQVANVGVEDARTLSVTVFDRSAIQAVEKAIMSSDLGLNPMSAGATLRIPLPALTEERRKDFIKVVRAEAEGGRVAIRNVRRDAISDVKKLEKAKECTEDDVRRFEDEVQKFTDAHIKKVDEILAAKEIELMEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMNRE_PSEAE
Sequence: MSDDIKVLGISGSLRSGSYNSAALQEAIGLVPPGMSIELADISGIPLYNEDVYALGFPPAVERFREQIRAADALLFATPEYNYSMAGVLKNAIDWASRPPEQPFSGKPAAILGASAGRFGTARAQYHLRQTLVFLDVHPLNKPEVMISSAQNAFDAQGRLLDDKARELIQQQLQALQLWVRRLRG
What is the function of this protein?
Has NAD(P)H-dependent FMN reductase activity.
What are the official names of this protein?
NAD(P)H-dependent FMN reductase PA1204.
What is the protein family that this protein belongs to?
Belongs to the SsuE family.
Protein: NF70_DORPE
Sequence: MSVTQKKTEISTTTTYEGESRPSSGMSGFSYSAKIHPRTSGYINRSSQSPFRSSMGSNAAYTRSYDFSYGATAMPGRYANISSTGVNHVKANREREKQDMRDLNERFANYIEKVRFLEAQNKKLAGELEELKSKWGKETSAIKEMYETELEEARKLIDATNKEKITLDVRVTELIDQLERQQKDLEESRTYHQIDQEQIARQNQQLADLEGEISMLRRSIESLEKEKMRQSNILAKMNDEMEKMRMDLNNETINHLDAENRRQTLEEELEFQKDVHAQELKELAALAYRDTTAENREFWRNELAQAIRDIQQEYDAKCDQMRGDIEAYYNLKVQEFRTGATKQNMEVTRNKEENTKLKSNMTEIRNRLADLEARNAQLERTNQDLLRDLEEKDRQNELESCQYKEEITKLRGEMESILKELQDLMDIKLSLELEIAAYRKLLEGEESRVGMKQIVEQVVGARPNEAEVLSTILTRSEGGYEATGDSQISMKMMRGELAAKTTYQRTSKGSVSIKEADSQGCFIALETKKEENLTGWKIVRKVDDNKVYTYEIPNLVLKTGTVVKIWSKNHQAQARGDDLVSRENDTWGTGSNVVTILQNEKGEDKANYTQNTVYQ
What are the official names of this protein?
70 kDa neurofilament protein, NF70.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: ROA1_RAT
Sequence: MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALCKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPRNQGGYGGSSSSSSYGSGRRF
What is the function of this protein?
Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and modulation of splice site selection.  Plays a role in the splicing of pyruvate kinase PKM by binding repressively to sequences flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform.  Binds to the IRES and thereby inhibits the translation of the apoptosis protease activating factor APAF1.  May bind to specific miRNA hairpins.
What are the official names of this protein?
Heterogeneous nuclear ribonucleoprotein A1, hnRNP A1, Helix-destabilizing protein, HDP, Single-strand RNA-binding protein, hnRNP core protein A1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Shuttles continuously between the nucleus and the cytoplasm along with mRNA. Component of ribonucleosomes.
Protein: CAMK_RHOSO
Sequence: MKQLATPFQEYSQKYENIRLERDGGVLLVTVHTEGKSLVWTSTAHDELAYCFHDIACDRENKVVILTGTGPSFCNEIDFTSFNLGTPHDWDEIIFEGQRLLNNLLSIEVPVIAAVNGPVTNHPEIPVMSDIVLAAESATFQDGPHFPSGIVPGDGAHVVWPHVLGSNRGRYFLLTGQELDARTALDYGAVNEVLSEQELLPRAWELARGIAEKPLLARRYARKVLTRQLRRVMEADLSLGLAHEALAAIDLGMESEQ
What is the function of this protein?
Catalyzes the carbon-carbon bond cleavage of the bicyclic beta-diketone 6-oxocamphor via a retro-Claisen reaction to yield the optically active (2R,4S)-beta-campholinic acid.  It is also able to cleave 2,2-disubstituted cyclohexa-1,3-diones such as 2-methyl-2-propylcyclohexa-1,3-dione and 2-methyl-2-butylcyclohexa-1,3-dione which result in racemic keto acid products.  Transformations of the bicyclic diketone substrates bicyclo[2. 2. 1]heptane 2,6-dione and bicyclo[2. 2. 2]octane-2,6-dione yield (S)-keto acid products.
What are the official names of this protein?
6-oxocamphor hydrolase, OCH, Beta-diketone hydrolase.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.