PharMolix/UniProtQA huggingface dataset:
Protein: SPTC3_MOUSE
Sequence: MANLNDSAVTNGTLHNPKTQQGKRQSTGCVKNGISKEAQQNRKAYAEDKPVFEPYQEAPLYVYVLTYMGYGIGILFGYLRDFMRNWGIEKCNAAVEREEQKDFVPLYQDFENFYKRNLYMRIRDSWSHTVCSAPEPYMNVMEKVTDDYNWTFRHTGKVIENIINMASYNYLGLAGKYDDSMVRVKDTLEKYGVGVASTRNEMGTLDIHKELEDLMAEFLNVEAVMSFGMGFATNAMNIPVFVGKGCLILSDEFNHTSVILGSRLSGAVIRPFKHNNAENLEKLLREAIIRGQPGTGRAWKKILIVVEGVYSMEGSIVNLAQIVALKKKYKAYLYIDEAHSIGCTGPTGRGVRELFGLDPEDIDVYMGTFTKSFSGSGGYIGGKKEIVDYLRMQSHSTTYATSMSPVVAAQLIRSLKITMGYEGNIGGMERIQQLKENIKYFRRRLKEMGFIIYGNDFSPVIPVLLYMPAKVSAFSRFLLKKKISVVVVGFPATSLPEGRARFSMSSAHTREMLDTVLEVVDELGDLLNVKYFPLKKSGRAILYNKEGFDNEASFEEMHSEPEA
What is the function of this protein?
Serine palmitoyltransferase (SPT).  The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core.  The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference.  SPT complexes containing SPTLC3 generate shorter chain sphingoid bases compared to complexes containing SPTLC2.  The SPTLC1-SPTLC3-SPTSSA isozyme uses C12-CoA, C14-CoA and C16-CoA as substrates, with a slight preference for C14-CoA.  On the other hand, the SPTLC1-SPTLC3-SPTSSB has the ability to use a broader range of acyl-CoAs without apparent preference.
What are the official names of this protein?
Serine palmitoyltransferase 3, Long chain base biosynthesis protein 2b, LCB2b, Long chain base biosynthesis protein 3, LCB 3, Serine-palmityl-CoA transferase 3, SPT 3.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: BIOF_PETMO
Sequence: MDFYEQLREELKKLEDSGLLITIRTLESAQGAWININGKKVLNMCSNNYLGLANNERLKEAAINAIKNWGVGPGAVRTIAGTMKIHEELEKKLAEFKKVEATLVVQSGFNANQAVIPTITNEEDGILSDELNHASIIDGVRLSKAKRYIWKHKDLNSLEEQLVKAQRDNCRRKLIITDGVFSMDGDIAPLPGIVELAKKYDALVMVDDAHGEGVLGENGRGIADHFNLTEEVDIEIGTLSKAFGVVGGFIAGKKVLIDYLKQQARPFLFSSSLSPAETAAALEATKILYESDDLVKKLWDNAKYFQSKIKEMGYDIGGTETPITPVMIYDEKKTKEFSSKLYEEGIFASSIVYPTVPKGKARIRVMISALHSKEDLDFALSKFEKIGKSLGTL
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase, Alpha-oxoamine synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: MFA1_USTMA
Sequence: MLSIFAQTTQTSASEPQQSPTAPQGRDNGSPIGYSSCVVA
What is the function of this protein?
Mating pheromone for A1 allele.
What are the official names of this protein?
A1-specific pheromone, Mating factor A1.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: SYH_FINM2
Sequence: MIQPSTLPGMMELLPEDQLVFDTIKRKIEDVFIKNAFFSIDTPAIEKLDVLLSKGGGETSKQVFRIDNSKKNQGLRFDLTVPLAKYVSMYMQDLAFPFRRYQIAKVYRGERNQKGRYKEFYQCDIDIIGNEKLSLYNDAEIVKCMYEALKSIDVPEFEFQFNNRKILNGYFSYLGIDDFESCLRVIDKLDKIGIDNVKEELSKINLDASKIDTLLKFLEIDGTNQEIIEKLESLNIDNELFTCGVNELKFVYQDILSLGVNPENIKINLSITRGLDYYTGSVFETFFKDYREIGSICSGGRYDSLANNFTKSKLPGVGMSIGLTRLFYQLQELNLVKGKQTNFDCIIIPMKGYEKNAVKLMNDLRNSSVKCMSYLEDDKLKKKFNYADKLSVKYVIIIGQDEVEQNKFTLRNMENGNQELLELNEIIEKLK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURT_BURO1
Sequence: MQIGQRLGTPLSPSATRVMLLGAGELGKEVIIALQRLGVEVVAVDRYPDAPGHQVAHRAHVIDMTDPAALRAIVEAERPHLIVPEIEAIATDALAAIEAAGLAEVIPTARATQLTMNREGIRRLAAEELGLPTSPYAFADSFEAFSAAVAKIGMPCVVKPVMSSSGKGQSVVKTDADVKPAWDYAMAGGRVNHGRVIVEGFVDFDYEITQLTVRAIDPATLDTRTYFCEPVGHVQVAGDYVESWQPQPMSAVALEKSREIAHKVTEALGGRGLFGVELFVRGDDVWFSEVSPRPHDTGLVTLASQRQSEFELHARAILGLPVDPALGTPAASAVIYGGLDERGIAFEGVRDALAVPGADLRLFGKPESFAKRRMGVALATGATVDEARERAKRAAAAVRPVSAR
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: Y1504_STRPI
Sequence: MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEYLAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKIVFEPVSELLK
What are the official names of this protein?
UPF0342 protein SPH_1504.
What is the protein family that this protein belongs to?
Belongs to the UPF0342 family.
Protein: ATG12_ASPFU
Sequence: MDSPSPENPSGTESPNPKSPQTTGTRLSHRPASRQKPALDSNTRSAPIPDDEHGADLPITMSASVVLSSLPRDAHRALADAEAVDTGKVTVRFQPLPSAPILKNRVFKISASQKFETVVKFLRKKLDCKDTDSVFCYVNSVFAPGLDEGVGGLWRCFKTDDQLIVSYSMTPAFG
What is the function of this protein?
Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.  Conjugation with atg5 through a ubiquitin-like conjugating system involving also atg7 as an E1-like activating enzyme and atg10 as an E2-like conjugating enzyme, is essential for its function.  The atg12-atg5 conjugate functions as an E3-like enzyme which is required for lipidation of atg8 and atg8 association to the vesicle membranes (By similarity).
What are the official names of this protein?
Ubiquitin-like protein ATG12, Autophagy-related protein 12.
What is the protein family that this protein belongs to?
Belongs to the ATG12 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: DXR_PROMP
Sequence: MLGSTGSIGTQTLEIVSELPDKFKVVALSAGRNIDLLTEQVSQHKPEVIAIEDENLLTDLKNNINNLGISNPPIVLGGREAINSVAAWDSADTVITGIVGCAGLIPTMSAIKAGKNIALANKETLIAAGSVVIPALKESKSRLLPADSEHSAIFQCIQGLPNYENADFSTGQIPNGLKAIHLTASGGAFRDWEVEDLKNVTVEDATSHPNWSMGRKITVDSATLMNKGLEVIEAHYLFGTSYENIEIAIHPQSIIHSMIEMEDSSVLAQLGWPDMKLPILYAMSWPERFKTNWKRFNLTEIGQLTFKKPDEVKYPCMGLAYSAGKCSGTMPAVLNAANEMAVDQFLKEKISFQEIPIFINKTCESHLNKINLNPKLEDILEVDNWARIFVQEEIKKGKKYINVG
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: MTNB_PARL1
Sequence: MVPRLDFAEAAKGVIAMARFAGARGWVPATSGNFSVRMNELSAALTATGANKAELDENGVIEAEIAGAKHPRASAEAPLHLARYRAAPGIGAISHMHSMAATVLSRRHAGTGAVRLEGWELMKAFAGVTTHDMSIDIPIVPNDQDTDRLAALVEERLDKDSICPGYLIAGHGLYVWGASAAETIRHMEAFDFLLTAQLHEESAR
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
What are the official names of this protein?
Methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
Protein: PAM17_CANAL
Sequence: MFSLGVQSRLFTRRALFSGFRFNSTTTTTTTASQPRLTWVDYFQLKKQNNRINTIAGVFTGLGGAFITLSYLGNIEIDVEKPIMGFDPLMVMGGAVILGGLVGFLVGPFIGSSIFRLTNRAQLKQFELKNTEFLSRLRIKRPDPSSQSFSNPIPDYYGEKIYSLKDYKQWLRDCNAFRRKSKEFL
What is the function of this protein?
Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
What are the official names of this protein?
Presequence translocated-associated motor subunit PAM17, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PAM17 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SIR24_CAEEL
Sequence: MTSVYESLLSDYPDKGVIGKPEIRDTETEIIEKLRTLYNHFVQAKQTGKPIFVLIGAGVSTGSKLPDFRGKQGVWTLQAEGKHAEGVDFQVARPGVSHKSILALHKAGYIKTIITQNVDGLDRKVGIPVEDLIEVHGNLFLEVCQSCFSEYVREEIVMSVGLCPTGRNCEGNKRTGRSCRGKLRDATLDWDTEISLNHLDRIRKAWKQTSHLLCIGTSLEIIPMGSLPLDAKSKGIKTTTINYQETAHEKIVETAIHADVKLILYSLCNALGVNVDLGDDLPDEVPIPLKIS
What is the function of this protein?
NAD-dependent protein deacetylase.
What are the official names of this protein?
NAD-dependent protein deacetylase sir-2.4, Regulatory protein SIR2 homolog 4, SIR2-like protein 4.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class IV subfamily.
Protein: FAR8_SARBU
Sequence: AGGADNFMRF
What are the official names of this protein?
FMRFamide-8, SabFMRFamide-8.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: STS1_PYRTT
Sequence: MNVQYQAFTPPHLLNNTRRSPTRNISSLSSAMSGRKRKAEDDGSAGDDDRMSASPSASPAVLPRPAPRGMKRMRTNISGRPLPLPRLLETLSPDEMRNLLQSICQRHPDISNEIVTTAPRPSIQSTLEVLAKYEASFQAAFPFGGRASSDYAYNRVRQQLDELLDSLKDFTPHFLPPNEQQPATSLAFLDGATDIIHRLPNWDTFQHNRHKQEAYEEMAKAWAIVIREAAKKAGGIQLQYGGWDEKIAKHNEISGGKMQEAVNELRGGLGWMGAETSNSAAGAPADAMSIRQQLLSGNYGAGSPASIGAW
What is the function of this protein?
Involved in ubiquitin-mediated protein degradation.  Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates.  Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins (By similarity).
What are the official names of this protein?
Tethering factor for nuclear proteasome sts1.
What is the protein family that this protein belongs to?
Belongs to the cut8/STS1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PTA_SHIFL
Sequence: MSRIIMLIPTGTSVGLTSVSLGVIRAMERKGVRLSVFKPIAQPRTGGDAPDQTTTIVRANSSTTTAAEPLKMSYVEGLLSSNQKDVLMEEIVANYHANTKDAEVVLVEGLVPTRKHQFAQSLNYEIAKTLNAEIVFVMSQGTDTPEQLKERIELTRNSFGGAKNTNITGVIVNKLNAPVDEQGRTRPDLSEIFDDSSKAKVNNVDPAKLQESSPLPVLGAVPWSFDLIATRAIDMARHLNATIINEGDINTRRVKSVTFCARSIPHMLEHFRAGSLLVTSADRPDVLVAACLAAMNGVEIGALLLTGGYEMDARISKLCERAFATGLPVFMVNTNTWQTSLSLQSFNLEVPVDDHERIEKVQEYVANYINADWIESLTATSERSRRLSPPAFRYQLTELARKAGKRIVLPEGDEPRTVKAAAICAERGIATCVLLGNPAEINRVAASQGVELGAGIEIVDPEVVRESYVGRLVELRKNKGMTETVAREQLEDNVVLGTLMLEQDEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPEQVYVYGDCAINPDPTAEQLAEIAIQSADSAAAFGIEPRVAMLSYSTGTSGAGSDVEKVREATRLAQEKRPDLMIDGPLQYDAAVMADVAKSKAPNSPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQSAQQQ
What is the function of this protein?
Involved in acetate metabolism.
What are the official names of this protein?
Phosphate acetyltransferase, Phosphotransacetylase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LDH_CUTAK
Sequence: MSTFDATRRASKISVVGAGSVGSSLAYACLIRGSAGLVSLYDIAKDKVEAEVADLAHGTQFTPASVMGGADVHDTADSDVVFITAGARQKPGQTRLDLAGVNANILRSLMPQLVEQSPNALFVLVTNPCDVLTVVAQEATGLPANRVFSTGTMLDTSRLRWLIRQWANVEQRHVHATIVGEHGDSEFPLWSTANISGVPIRDWAVDGNRVFTEDVLADLAHEAAYAAYKIIEGKGATNYAIGLTGARLAEALLRPGRSVLPLSSVMTDMHGISGVALSMPCIVSRDGIEGVVPVAMDTEEIASLKASAERLHDTLSSIA
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSHM_SARGL
Sequence: MNQIPMQYFNLAKENYSKYGLSVIQLIQIGKFYELWHEPDTSSKQQAYSQAELLVESSIRSRSLEVTPPIEQVASLLDMKIISLGKRSLLQMGFPVYSLTTHLSTLLDKGWTVIVIDELVTNKSGPKQRAVSQVYSPSCNLEDCPELPYVLSIYFSQDDLLGITLFSAMNGHSIIFPVSWTDRDKVTRLLISYHIREIVIWADSGVCSNILINKIYNLLIGWNLFPSEPNAKIEAMGEILTNLPCYLSYRYENNSKEWLLLHIYIGINTEWLNKNYQKYTLSKIFQSTWTENVNQANLISLLGVLQFIKDRNPNLIKNLQLPECYNSVVSPLNLILCNRAEYQLDLLSKRGKLGGLLNLIDYCSTAMGKRLLKFRLLNPITDYSELNLRYKDISIFKRLLNQKIFDNSELKCIKDLSSLHRQWAICASSDTTLPPKKLSQIYHSYLFACQLISKLTNNIQLPPLVGPQLKSLIKEIERIFQVDSLLGDFKDVIQPIGNLPNLFEQRQTLRAQLTEWAEQISNIVFQDTTSIKAEYFNKEGYAFSISSKKLTKLEHYMMNTSISNNSIIVLGKRGSHHIITSPTIHKVSIELNELEEQINIYVKQTYHQELKRLYFSYSELFLPLVNMISRLDVALSGAITAIKFNYVEPCLTLAKTQQTKGFIEAANLRHPLVEQLNTQEECIAHNISLEDKGMLVFSVNGAGKSTLLRAIGVNVILAQAGMYVAADSFKLRPYNYLITRILGGDDLYRGQGTFEVEMRDLSTILQLANYNSLILGDEICHGTEVNSGTAILAATIERLINAQTSFVLSTHLHQVCSLIDSPVRYYHLSVIQQENSALIYERKLKPGPGPSQYGIEVMGHIINDKKFYNSALKYRKLINWEPPSQGELTVFRPSKYNAQVFIDSCEICGAPADAVHHIKPKSEHKKLCNRKLNRRSNLVPVCSSCHLDIHRNKISILGWKRTPKHKKLYWVYTNESLDSGTK
What is the function of this protein?
May be involved in DNA-mismatch repair.
What are the official names of this protein?
Mitochondrial DNA mismatch repair protein mutS homolog.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CAPP_VIBPA
Sequence: MNEKYAALKSNVRMLGHLLGNTIRDAHGEEIFEKVETIRKLSKSAQAGNQADRESLIEEIKHLPDEQLTPVTRAFNQFLNLTNIAEQYHTISRHCEEHICEPDAINSLFSKLVQNDVSKLDTAQAVRDLNIELVLTAHPTEITRRTMINKLVKINECLSKLELSDLSSKERKKTERRLEQLIAQSWHSDVIRQQRPTPLDEAKWGFAVVENSLWEAVPDFLREMNDRLKSYLGEGLPIDARPVHFSSWMGGDRDGNPFVTHSVTREVLLLSRWKAADLYLNDINELISELSMTVSNDQVRELAGEDQHEPYRAILKQLRALLNETKDILDAKIHGQKLAVKAPLQKVEQLWDPLYACYQSLHECGMGVIADGSLLDTLRRVKAFGVHLVRLDIRQESTRHADVLSELTRYLGIGDYEQWSEQDKIAFLTNELASKRPLLPRDWEPSEPVKEVLDTCKIIALQPREAFGAYVISMARTASDVLAVHLLLQEAGCPYRMDVCPLFETLDDLNNAESVIKQLMSIDLYRGFIQNHQMVMIGYSDSAKDAGVMSAGWAQYHAMESLVKVAEDEGVELTLFHGRGGTVGRGGAPAHAALLSQPPKSLKGGLRVTEQGEMIRFKLGLPDVAVNSFNLYASAILEANLLPPPEPKQEWRDLMEVLSEVSCEAYRGVVRGEPDFVPYFRQATPELELGKLPLGSRPAKRNPNGGVESLRAIPWIFSWSQNRLVLPAWLGAGEAIQYSVDKGHQALLEEMCREWPFFSTRLGMLEMVYTKCNMEISRYYDQRLVEPQLQPLGDRLREQLQRDIKSVLNVENNENLMQSDPWGQESIRLRNIYVEPLNMLQAELLYRTRQTEEASANLEEALMVTIAGIAAGMRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: TREH1_SULAC
Sequence: MLGMKPLGFIGNGLTSALVDNGSIVWLTFPRFDSPSVFGKLLDDNAGEFSIRPVEDKFKVSQSYLVPNVLSTTFKSSNGKAEIVDLMPIGEKAIIRKVRTEIPLSFKIIPMFNYGLYRPIIRRKDDGIQFLNPVSRECLSLLSDVPTDEIKPPGTTLYLVYSSDCAYGPLDKGKQLENDLENSFNLTIDYWKDKIRSNDEVWRTSVGVLLGLIYSPSGSSIAAATTSLPEAVGDSRNWDYRFVWVRDSSMISEALLYSGYVVEARRILNFMLALVNFTAKPLLHPLYAVDGSDPPPEIEIPWLSGYMNSRPVRVGNAAASQIQLDIEGFLVDAIYKYYKYTSDRVFVEENWDKIKYIGDWVSKNWMLKDAGMWEDRGDPKHYTHSKVMMWVALDRIEKIMNVKIHEKDEIKEWVMRNCVKDGSFVRSSDSNDVDANLLTLPLYDFIDVKDPIFLKTLKRIEDELYVDGFVKRYSQDFMGEAKHPFALATIWLARVYIRLGRKERAMELLDKVLKPSGTLYLIGEHIDVENMEYTGNYPQAFVHAQLLLALKEVKGLST
What is the function of this protein?
Catalyzes the hydrolysis of alpha,alpha-trehalose into two molecules of D-glucose.
What are the official names of this protein?
Trehalase 1, Alpha,alpha-trehalase, SaTreH1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 15 family.
Protein: TPIS_MYCSK
Sequence: MARKPLIAGNWKMNLNHFEAIALVQKIAFSLPDKYFDKVDVTVIPPFTDLRSVQTLVDGDKLRLSYGAQDVSQHDSGAYTGEISGAFLAKLGCSFAVVGHSERRTYHHEDDALVAAKAAAAFRHGITPIVCIGEHLKVREAGNHVEHNVEQLRGSLAGLTSEQIGQAVIAYEPVWAIGTGRVAGAADAQEVCKAIRDELGKLSSPQLAAGIRVLYGGSVNAKNVGEIVAQEDVDGALVGGASLDGEQFATLSAIAAGGPLP
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPA_BUCAI
Sequence: MNFFIKSCFLDKEKTDCIVVSVFELSELSDSAIYLDKCSNGHITSLIKLGDIQGKIGDTLMLYKVPKILSKRILLVGCGKKDEINIIRFKKILKNTIHAIKKKSITNIVYSFSNINIDNIYWMIRRMVLSLKESLYETIKINNINIKNTNIHSITLNIIKKNDLFIAKTALKHALAIDHAITSTKNLSNLPPNICNPLYLSYKAQELSKKYENNIVVEIIDIKKMKELGMNAYIAVGNGSKNKPFMSVIKYSGNNIVNKKIIAFVGKGLTFDSGGISIKPALHMHEMKYDMCGAAAVYGTLIMAAELQLPLTVIGILSGCENMVGSHSFRPGDVLTTMSGQTVEILNTDAEGRLVLCDSLTYLERFSPDIVIDVATLTGACVTALGESVSGLFSNNEELSNQLLHASQETDDKIWSLPLFSEYHKELNSDIADFSNIGRGKAGAITAACFLSKFTKKYNWAHLDIAGTAWKSGKKSGATGRPVELLCQFLLNQSNYIYN
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity).
What are the official names of this protein?
Cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_WOLPM
Sequence: MNIGRAIKVTQAVVDIKFEGELPKIFNALKSKLKYKDKELVLEVSQHIGDNIVRCIAMDSTDGMSRGDEFVDTGAPISVPIGRSTLGRIFNVVGELIDECGPLKGKYNLEPIHRAPPSFTEQRIQEEVLVTGIKVIDLLAPYLKGGKIGLFGGAGVGKTVLIMELINNIAKAHKGFSVFAGVGERTREGNDLYHEMITSNVININEHEKSQAVLVYGQMNEPPGARARVALTALTMAEYFRDRENQDVLFFVDNIFRFTQAGSEISALLGRIPSAVGYQPTLATDMGAMQERIASTTSGSITSVQAIYVPADDLTDPAPATTFSHLDATTVLSRQIAEMGIYPAVDPLDSTSQSLSAEIIGEEHYNVASEVKRILQTYKSLQDIIAILGMDELSDEDKIIVDRARKIQKFLSQPFHVAEIFTGMPGKFVSLSDTVSSFKGIVEGKYDHLPEAAFYMVGNIDEAIKKAELIQAEAK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: Y270_SYNY3
Sequence: MINPQPDEKELLKTILEPLLGDFEHWFSRSCQLLESQRLVFFTPEQQQELLDRVRQARDEVKCTKLMFQATGEQVGVEFSVLVPWHNLVTECWQVAQRHRQMQAAR
What are the official names of this protein?
Uncharacterized protein slr0270.
Protein: LRRC7_RAT
Sequence: MTTKRKLIGRLVPCRCFRGEEEIISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSSLPTSIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFSELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPPTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQRLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQSKALIPLQTEAHPETKQRVLTNYMFPQQPRGDEDFQSDSDSFNPTLWEEQRQQRMTVAFEFEDKKEDDESAGKVKALSCQAPWDRGQRGITLQPARLSGDCCTPWARCDQQIQDMPVPQSDPQLAWGCISGLQQERSMCAPLPVAAQSTTLPSLSGRQVEINLKRYPTPYPEDLKNMVKSVQNLVGKPSHGVRVENANPTANTEQTVKEKFEHKWPVAPKEITVEDSFVHPANEMRIGELHPSLAETPLYPPKLVLLGKDKKESTDESEVDKTHCLNNSVSSGTYSDYSPSQASSASSNTRVKVGSLQPTTKDAVHNSLWGNRIAPPFPQPLDAKPLLTQREAVPPGNLPQRPDRLPMSDAFPDNWTDGSHYDNTGFVSEEATGENANNNPLLSSKARSVPAHGRRPLIRQERIVGVPLELEQSTHRHTPETEVPPSNPWQNWTRTPSPFEDRTAFPSKLETTPTTSPLPERKDHMKEPTETPGPFSPGVPWEYHDPTPNRSLGNVFSQIHCRPDSSKGVIAISKSTERLSPLMKDIKSNKFKKSQSIDEIDVGTYKVYNIPLENYASGSDHLGSHERPDKFLGPEHGMSSMSRSQSVPMLDDEMLMYGSSKGPPQQKASMTKKVYQFDQSFNPQGAVEVKAEKRIPPPFAHNSEYVQQPGKNIAKDLVSPRAYRGYPPMEQMFSFSQPSVNEDAMVNAQFASQGPRAGFLRRADSLASSTEMAMFRRVSEPHELPPGDRYGRAAYRGGLEGQSSVSMTDPQFLKRNGRYEDEHPSYQEVKAQAGSFPAKNLTQRRPLSARSYSTESYGASQTRPVSARPTMAALLEKIPSDYNLGNYGDKTSDNSDIKTRPTPVKGEESCGKMPADWRQQLLRHIEARRLDRTPSQQSNILDNGQEDVSPSGQWNPYPLGRRDVPPDTITKKAGSHIQTLMGSQSLQHRSREQQPYEGNINKVTIQQFQSPLPIQIPSSQATRGPQPGRCLIQTKGQRSMDGYPEQFCVRIEKNPGLGFSISGGISGQGNPFKPSDKGIFVTRVQPDGPASNLLQPGDKILQANGHSFVHMEHEKAVLLLKSFQNTVDLVIQRELTV
What is the function of this protein?
Required for normal synaptic spine architecture and function.  Necessary for DISC1 and GRM5 localization to postsynaptic density complexes and for both N-methyl D-aspartate receptor-dependent and metabotropic glutamate receptor-dependent long term depression (By similarity).
What are the official names of this protein?
Leucine-rich repeat-containing protein 7, Densin-180, Densin, Protein LAP1.
What is the protein family that this protein belongs to?
Belongs to the LAP (LRR and PDZ) protein family.
What are the subcellular locations of this protein?
Cytoplasm. Postsynaptic density.
Protein: GCH1L_ARCFU
Sequence: MNLAEVVRFLDDFLEINSYQDVSNNGLQVEGSEEVKKVAFAVDASMESFRAAKAVNADMLVVHHGLIWGGIGYIRGIVKRRIEFLLRSNLSLYAAHLPLDAHREVGNNAVILRKIGAEPQEEFGEYKGVKIGFSAKLEKATAVGEIAEKLGPAMVLPFGEERVRKVAAVSGKGCFALNEAIDAGVELFITGEPEHEAYHLAKEGGINVFFLGHYESEKFGVQSLMEVVREKLGIEAVFLDIPTNL
What are the official names of this protein?
GTP cyclohydrolase 1 type 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
Protein: DNAA_SYNJA
Sequence: MDISLDRLWDEALGHLQVQLSRPTFEAWIKTARAESLVDNRLTISTPSEWARGWLQKHYASTITEVVQRVAGIPLQVEFSVAPQALVEEEAPSTAVASTSRKAGSFPASAPLGLEVSGSLPMRAPDLNPKYSFSRFVVGPNNRMAHAAALAVADKPGRAYNPLFLCGGVGLGKTHLMQAIGHYQLEANPRAKVFYVSTERFTNDLIDAIRRDSMQSFREHYRDVDILLVDDIQFIEGKEYTQEEFFHTFNTLHESGKQIVLAADRSPHLIPRLQERLCSRFSMGLIAEIQPPDIETRMAILKKKAEYEGMILPPEVIEYIATTYTSNIRELEGALIRAVAYVSISGLPMSVETIQPILNPPSEPKEITPDMIIDVVCEEFGVDRESLLGSSRKRDISQARQIAMFLMRHHTNLSLPKIGDYFGGKDHTTVLYSCEKVSQLQRENLQFERQLQNLAQRLRVMANSRNR
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPGD1_POGCB
Sequence: MDLNEITSSSRPLANYHPNVWGDRFLLHEPEFTCQAGEKQLVEELKEEVRRELKEASNDYLRQLKMVDAIQRLGIEYLFEEEIDEALRNLLAKFENYCKDNHDMYATALSFRLLRQHGYKVSCEVFDKFKDGEDGFKVEEVMAVLELFEATHMRIHGEDVLDQAFVFTRNYLQSIHATLSNPIAKQVHNALNGYSCRRGMPRIEARKYIPIYEEYGCHHKALLKLAKLDFNLLQSMHKRELTQLYRWWKDLEMPTKLPYIRDRLVETYFWDMGFYFEPQYALARNILVKVQCLVSIFDDTFDAYGAFKELQLFKDAIDRWSISCLDELPEYMQIIYKLVLDVFEEIESHMIKQGTSYRLDYAREAIKIVIGGYFDEAKWREEEYKPRMEEYMKVATKSAAYLTLIIVSFVGMKNDIATPQAFQWVLSEPQIITASLALARLSNDLVGIEFEKERKYIATAVELYEEEHKVSKEEAVLELRHETESAWKEINEALLEPTTFATPILDRILNSARVLEVFYDKTDRYTHVDLELQNIIAQLYIHPIP
What is the function of this protein?
Sesquiterpene synthase involved in germacrene D biosynthesis.  Produces also at least 13 additional sesquiterpene products, including germacrene C and (+)-germacrene A, beta-ylangene, (E)-beta-farnesene and (E,E)-alpha-farnesene.
What are the official names of this protein?
Germacrene D synthase 1, PatTpsB15.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: ONCM_RAT
Sequence: MRAQPPPRTLLSLALALLFLSMSWAKRGCSSSSPKLLSQLKSQANITGNTASLLEPYILHQNLNTLTLRAACTEHPVAFPSEDMLRQLSKPDFLSTVHATLGRVWHQLGAFRQQFPKIQDFPELERARQNIQGIRNNVYCMARLLHPPLEIPEPTQADSGTSRPTTTAPGIFQIKIDSCRFLWGYHRFMGSVGRVFEEWGDGSRRSRRHSPLWAWLKGDHRIRPSRSSQSAMLRSLVPR
What is the function of this protein?
Growth regulator.  Inhibits the proliferation of a number of tumor cell lines.  It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells (By similarity).  Uses only type II OSM receptor (heterodimers composed of OSMR and IL6ST).  Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration.
What are the official names of this protein?
Oncostatin-M, OSM.
What is the protein family that this protein belongs to?
Belongs to the LIF/OSM family.
What are the subcellular locations of this protein?
Secreted.