PharMolix/UniProtQA huggingface dataset:
Protein: RNH2_CLOBH
Sequence: MNLNNLENIRYNEIKEFSDKIKKEFTFSQKKQVMDIIEKLNKDSRKNVIKLGQALEKFLNKYEEELKRTNNMYNFDRRYGNNYLIAGVDEVGRGPLAGPIVAAAVVLDLNVEEMQRIFNIKDSKKLSEKKREELDIIIREKAISYNIALVDNKTIDERGISWSNNEVLKRAVEGLKVKPDLVLSDGYAVKNLNIRNEFIIKGDSKSISIASSSIIAKVYRDSMMKEYSKGLNMYGFNHNAGYGTEEHVQAIKKHGPSKIHRMSFLTNIL
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCA_BORPE
Sequence: MRNTFLEFEQPLAELENKIEQLRYVQADSAVDISDEIGRLQQKSQNLAKEIYGKLTPWQTALVARHPQRPYTLDYVREIFTDFHELHGDRMYADDQSIVGGLARFNGSACMVIGHQKGRDTKERAARNFGMPRPEGYRKALRLMRLAEKFRLPIFTFIDTPGAYPGIGAEERGQSEAIGRNLYAMAELKVPVICTVIGEGGSGGALAIAVGNAVLMLQYATYSVISPEGCASILWRSADKAPEAAEALAITAPRLKDLGLVDRVVNEPVGGAHRDPRVMARLLRRALGDALRQLQGLGPEQLVDQRLQRLMSYGRFQEVRA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPHB_STAMF
Sequence: MLYFIGLGLSIKHLTLEAIDALRDVEKIYVDTYTNIVPDFSLDKLVSLVGEEKEFVMAKREFLEGKNIHFIVEEASKKNIAILVPGDPFIATTHDAIRVEALRRGIKVKVINGLSIYSLAPSRTGLQAYKFGKTVTLVYPEYFKPYSTIETIYDNLDRNLHTLLLLDLKIEENKAMTIPEAVDILIDLDERGVLENIIGVGLAQLGSSMEKIVADRLADLKNYTYPPPPHSIIIVAKPHPIELDNLHYVCGLPEHIYRRYSVSKTYP
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine.  The three successive methylation reactions represent the second step of diphthamide biosynthesis.
What are the official names of this protein?
Diphthine synthase, Diphthamide biosynthesis methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the diphthine synthase family.
Protein: LSPA_YERPS
Sequence: MNKPICSTGLRWLWLAVVVVILDISSKQWVMAHFALYESVPLIPFFNLTYAQNFGAAFSFLADKSGWQRWFFAGIAIGISVVLMVMMYRSTAKQRLINCAYALIIGGALGNLYDRLVHGAVNDFLDFYINNWHFPTFNLADVAICIGAALVIFEGFLSPVEKNAVNNDE
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PDXT_RUBXD
Sequence: MAGRRNGHAGRPRVGVLALQGDFREHAEILERLGAEPVEVRRPEDLRGLDGLIIPGGESTAIGNLMVHSGMLDAIRSFFYQGGAVWGTCAGMVLAASATTGPSQPLLGIMSALVERNGFGRQVHSFEADLEVKGFDRPFRGVFIRAPYFEDVGPGVEVLAEIDGRVVAARAGKVLVTAFHPELTDDTRFHEYFLREVCGSDERS
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: RL2_DESOH
Sequence: MGIRKVKPTSPGRRFQEYSTFEEITADRPSEKGLIEPLRKTGGRNVNGRITCRHRGGGHKRHYRVIDFKRNKDDIPAKVAAIEYDPNRSARIALLFYADGEKRYILAPVNLKVGDTVMSGQASEIKPGNAMPLASIPLGTEVHNIELRLGKGGQIVRSAGGYAKVMAKEARYVLLRLPSSEMRKVLATCKATIGRVGNVEHDDVSIGKAGRNRWLGKRPRVRGVAMNPVDHPMGGGEGKSSGGRHPCSPWGQQSKGVRTRNNKRTDQFIVKRRSK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: DSBD_YERE8
Sequence: MAQRFITLILLLCSILLAPHSAQASLFGDNSSFGQKSSQSRFIPVDQAFAFDFRQQGDQLALSWQIHPDYYLYRQQIKIVPNNATFGAFTLPEGIAHRDEFYGEVAIFKQQLTLKIPITQAGERASVSVTYQGCAEAGFCYPPETRVVPLSAITAGSSAVTAPPIAAPATPAPAELPFSPLWALLIGIGIAFTPCVLPMYPLISAIILGREKPHSQRRILLLAIVYVQGMALTYTLLGLVVAAAGLQFQAALQHPYVLIGLSALFVLLALSMFGLYSLQLPSSLQTRLVQWSSSQRGGSLAGVFAMGALAGLICSPCTTAPLSAILLYIAQSGNMLAGGGTLYLYALGMGIPLVIVTLFGNKLLPRSGPWMQYVKEAFGFVILALPVFLLERVLGDVWGLRLWSLLAIAFFGWAFILSLKAHSGWARAFQLLLLAALLIAARPLQDWAFGSPTQQSEIKHLAFKQVADLPQLQAALAQAKGKPVMLDLYADWCVACKEFEKYTFSDEQVQRQLADTVLLQADVTANSAEHAALLKELNVLGLPTILFFDAPGNEIPAARVTGFMNASGFLQHLQNLPR
What is the function of this protein?
Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes.  Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm.  This transfer involves a cascade of disulfide bond formation and reduction steps.
What are the official names of this protein?
Thiol:disulfide interchange protein DsbD, Protein-disulfide reductase, Disulfide reductase.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. DsbD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NU4M_PONAB
Sequence: MLKLIIPTIMLLPLTWLSKTHMIWINTTTHSLIISSIPLLFLNQTNSNLYSYSLLFSSDPLSTPLLMLTTWLLPLMIMASQHHLSNEPPSRKKLYLTMLISLQISLIMTFTATELIMFYILFETTLIPTLVIITRWGNQPERLNAGTYFLFYTLVGSLPLLIALIHTYNTLGSLNIVLLTLTARELTDSWSNSLMWLAYTMAFMVKMPLYGLHLWLPKAHVEAPIAGSMVLAAVLLKLGGYGMMRLIPILNPLTKHMAYPFIMLSLWGMIMTSSICLRQTDLKSLIAYSSVSHMALVVAAILIQTPWSFTGATTLMIAHGLTSSLLFCLANSNYERTHSRIMILSQGLQTLLPLMALWWLLASLTNLALPPTINLLGELSVLMAMFSWSNITILLTGLNMLITTLYSLYMFTTTQRGTPTHHTNNMKPSFTRENTLMLMHLSPILLLSLNPSIIAGFAY
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL6_RHOOB
Sequence: MSRIGKIPVTVPGGVDVSIDGQDVTVKGPKGTLALTISEPIVIAKNDDGTLSVTRPDDERRSRALHGLSRTLVQNLITGVTDGYTTKMEIHGVGYRVALKGKDLEFALGYSHPVPIEAPEGITFAVESPTKFSVSGIDKQKVGQISANIRRLRRPDPYKGKGVRYEGEQIRRKVGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: TSAD_SODGM
Sequence: MRVLGIETSCDETGVAIYDQQQGLLANQLYSQVKLHADYGGVVPELASRDHVHKTVPLIQAALAEAGLQASDIHGVAYTAGPGLVGALMVGATVGRALAYAWGVPAVAVHHMEGHLLAPMLEANPPAFPFVALLVSGGHTQLIAVTGIGEYQLLGESIDDAAGEAFDKTAKLLGLDYPGGPMLARLAQQGVPGRYKFPRPMTDHPGLAFSFSGLKTFAANTVRAGADDHQTRADVARAFEEAVVDTLMIKCRRALDQTRFQRLVMAGGVSANQSLRASMGEMMRQRGGEVFYARPEFCTDNGAMIAYAGMVRLQGGSQASLAVSVRPRWPLEELPALGA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_SHEON
Sequence: MTTRYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPTQHGEVFVTEDGAETDLDLGHYERFIRTKMNRRNNFTTGRIYEEVLRKERRGDYLGATIQVIPHITNAIKEKVLAGGEGHDVAIVEIGGTVGDIESLPFLESIRQLGVELGRDRTLFMHLTLVPFLGAAGEVKTKPTQHSVKELRSIGIAPDVLICRGDRAIPANERAKISLFCNVEERAVISLKDVDSIYKIPALLRSQGLDELVVKRFSLTCREADLSEWENVIYQEANPNGEVVIGMVGKYIELPDAYKSVNEALKHAGLKNRVSVTIKYIDSQTVEAKGDEVLQGLDGILVPGGFGERGVEGKILAAKFARENNLPYFGICLGMQVALIEFARNVAGMADAHSTEFNKATPFPVVGLITEWVDEEGNVEQRHEASDLGGTMRLGAQLCHLLEGSKAAQAYKGNSCVERHRHRYEVNNKYKERLEQAGLVFSGLSSDRKLVEMIELKDHPWFVAGQFHPEFTSTPRDGHPLFEGFVAAASAHQKRDLKK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: GAPN_MAIZE
Sequence: MALAGTGVFAEILDGEVYRYYADGEWRTSASGKSVAIVNPTTRKTQYRVQACTQEEVNKAMDAAKVAQKAWARTPLWKRADVLHKAAAILKEHKAPIAECLVKEIAKPAKDAVSEVVRSGDLVSYTAEEGVRILGEGKLVVSDSFPGNERNKYCLSSKIPLGVVLAIPPFNYPANLAGSKIGPALIAGNALVLKPPTQGAVAALHMVHCFHLAGFPKGLISCVTGKGSEIGDFLTMHPGVNCISFTGGDTGIAISKKAGMVPLQMELGGKDACIVLEDADLDLVSANIVKGGFSYSGQRCTAVKVVLIMESIADAVVQKVNAKLAKLKVGPPEDDSDITPVVTESSANFIEGLVMDAKEKGATFCQEYRREGNLIWPLLLDHVRPDMRIAWEEPFGPVLPVIRINSVEEGIHHCNASNFGLQGCIFTRDINKAILISDAMETGTVQINSAPARGPDHFSFQGLKDSGIGSQGITNSINMMTKVKSTVINLPSPSYTMG
What is the function of this protein?
Important as a means of generating NADPH for biosynthetic reactions.
What are the official names of this protein?
NADP-dependent glyceraldehyde-3-phosphate dehydrogenase, Glyceraldehyde-3-phosphate dehydrogenase [NADP(+)], Non-phosphorylating glyceraldehyde 3-phosphate dehydrogenase, Triosephosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_ENT38
Sequence: MAAKIIDGKTIAQQVRSEVAVKVKARTAAGKRAPGLAVVLVGSNPASQIYVGSKRKACEEVGFVSRSYDLPETTTEAELLELIDTLNADEVIDGILVQLPLPAGIDNVKVLERIAPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTYGLNAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRQHVENADLLIVAVGKPGFIPGEWIKEGAIVVDVGINRLENGKVVGDVVYEDAAARASYITPVPGGVGPMTVATLIQNTLQACEEYHDVEEA
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: BAG3_MOUSE
Sequence: MSAATQSPMMQMASGNGASDRDPLPPGWEIKIDPQTGWPFFVDHNSRTTTWNDPRVPPEGPKDTASSANGPSRDGSRLLPIREGHPIYPQLRPGYIPIPVLHEGSENRQPHLFHAYSQPGVQRFRTEAAAATPQRSQSPLRGGMTEAAQTDKQCGQMPATATTAAAQPPTAHGPERSQSPAASDCSSSSSSASLPSSGRSSLGSHQLPRGYIPIPVIHEQNITRPAAQPSFHQAQKTHYPAQQGEYQPQQPVYHKIQGDDWEPRPLRAASPFRSPVRGASSREGSPARSGTPVHCPSPIRVHTVVDRPQPMTHREPPPVTQPENKPESKPGPAGPDLPPGHIPIQVIRREADSKPVSQKSPPPAEKVEVKVSSAPIPCPSPSPAPSAVPSPPKNVAAEQKAAPSPAPAEPAAPKSGEAETPPKHPGVLKVEAILEKVQGLEQAVDSFEGKKTDKKYLMIEEYLTKELLALDSVDPEGRADVRQARRDGVRKVQTILEKLEQKAIDVPGQVQVYELQPSNLEAEQPLQEIMGAVVADKDKKGPENKDPQTESQQLEAKAATPPNPSNPADSAGNLVAP
What is the function of this protein?
Co-chaperone for HSP70 and HSC70 chaperone proteins.  Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release.  Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70.  Has anti-apoptotic activity.  Plays a role in the HSF1 nucleocytoplasmic transport.
What are the official names of this protein?
BAG family molecular chaperone regulator 3, BAG-3, Bcl-2-associated athanogene 3, Bcl-2-binding protein Bis.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Colocalizes with HSF1 to the nucleus upon heat stress.
Protein: OSGI1_HUMAN
Sequence: MSSSRKDHLGASSSEPLPVIIVGNGPSGICLSYLLSGYTPYTKPDAIHPHPLLQRKLTEAPGVSILDQDLDYLSEGLEGRSQSPVALLFDALLRPDTDFGGNMKSVLTWKHRKEHAIPHVVLGRNLPGGAWHSIEGSMVILSQGQWMGLPDLEVKDWMQKKRRGLRNSRATAGDIAHYYRDYVVKKGLGHNFVSGAVVTAVEWGTPDPSSCGAQDSSPLFQVSGFLTRNQAQQPFSLWARNVVLATGTFDSPARLGIPGEALPFIHHELSALEAATRVGAVTPASDPVLIIGAGLSAADAVLYARHYNIPVIHAFRRAVDDPGLVFNQLPKMLYPEYHKVHQMMREQSILSPSPYEGYRSLPRHQLLCFKEDCQAVFQDLEGVEKVFGVSLVLVLIGSHPDLSFLPGAGADFAVDPDQPLSAKRNPIDVDPFTYQSTRQEGLYAMGPLAGDNFVRFVQGGALAVASSLLRKETRKPP
What is the function of this protein?
Regulates the differentiation and proliferation through the regulation of cell death.
What are the official names of this protein?
Oxidative stress-induced growth inhibitor 1, Bone marrow stromal cell-derived growth inhibitor, BMSC-derived growth inhibitor, Ovary, kidney and liver protein 38, huOKL38, Pregnancy-induced growth inhibitor OKL38.
What is the protein family that this protein belongs to?
Belongs to the OKL38 family.
Protein: HUTH_CHLAA
Sequence: MQIREVILDGESLTIEQVLAVAYGQPGTPVVRLAPIARQRVERAAQAVQDLLARGVVAYGITTGFGAFKDRVIAPDQVERLQYNILVSHAVGVGPVFDIPTTRAIMLIRANTLARGHSGVRLQTVERLLDMLNQGIHPRIPCKGSLGASGDLAPLAHMALPLIGLGEVEWQGEVLPAATALERLGWQPLHLAAKEGLALTNGTAVMCALGVIETARAETLSATADIAGCLSLEALYGTPAAFDARLHALRPFPRQIECAAHLRRLLAGSTFVRNNDPRHVQDAYTLRCIPQVHGAVRDAIAYARWVFAIELNAVTDNPLLFVDDDGNVEVISGGNFHGEPLAIALDYLGLAVAELGNIAERRLMRLTDEASNTHVLPAFLTRAGGLNSGFMIVQYTAAALATENKVLAHPASVDSIPTSANVEDHVSMGVTAGLKLRSIIDNVSQILALELFAAAQGIDFRRQELGSQARLGRGTGPVYELIRQYVPFIAEDTLLHPYITIISELVAQGKIAAAAAVHDDADA
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSA_JANMA
Sequence: MININGEIKVDNAAPFVLFGGINVLESRDLAMRSCEEYVRVTGKLGIPYVFKASFDKANRSSIHSYRGPGLEEGLRIFEDVKKTFGVPLITDVHEPYQAKIAAEVIDVLQLPAFLARQTDLVVALAQTGRVINIKKPQFLSPPQMLNIVEKFREAGNDKLILCDRGTCFGYDNLVVDMLGFGVMKKVTGNLPIIFDVTHALQQRDSLGTASGGRREQVADLARAGMGVGLAGLFLEAHPDPKVAKCDGPSALPLDKLEPFLAQLKQLDDLVKSFAPLDIEA
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLHD_YERPY
Sequence: MSTSELLKHIYDINLSYLLLAQRLINDEKASAMFRLGITDTMADALSQLTLPQMVKLAETNQLVCHFRFSDHNTIHHLTKESRVDDLQQIHTGILLSSHLLHELSLKDDSTPKKRA
What is the function of this protein?
Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region.  Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes.  Also regulates genes whose products function in a variety of physiological pathways.
What are the official names of this protein?
Flagellar transcriptional regulator FlhD.
What is the protein family that this protein belongs to?
Belongs to the FlhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUR32_SCHPO
Sequence: MEPILNQGYGYGFALGLGAAFALLMAIITKVLTACMGQTQNSERFSTASRSVKSGLISSSTVSAWTWPATLLSSGAWSYTYGIMGGFMYGVGGTIQITLFLFLAIQIKKKAPAAHTVSECFFIRFGKLGHCVYLFYCISTNVLVSSLLLLGGSQGFSSTTGMNTVAACFLLPLGVMVYTTLGGLKATFISDWIHTVMIYIILIVTCYTVYCSSSLIGSPAKMYDMLKEVQEVYPATGGQSYLSFKNSEMMYLTWSVMIGGLSSVFGDPGYSQRAIASDAKSVFQGYLMGGLCWWIIPMALGSSAGLACRALLLNPASVTYPNVLSSVEISSGLPVIYGMASIFGKSGAAAGLVMLFMSITSATSAELIAFSSVTTYDIFRAYINPAANGKQLVRTAHLSVIGFSLFIGALSVGFNYAGVTAGWLLTFLGIILTPEVSAVTLCLFWNKMTRFSLVVGAPFGTITGVVCWLASTYSFCDGIVNKDTVMTSKACFVGNIVSMASSPLYIVLLSYIWPDKETFDLNQFRNITVGDDIDTTELNAIVSQLKDERILKLQTYWSIGINLFILIGCYVIIPTALLGSNHDLSKSSFSGLIIVCLIWILVAAIYIILFPLWQGRKSLANVISHIIRLKAPENILLDGLTPKQSSEDVGDATSFHMDKLDKEKEKSSELKTA
What is the function of this protein?
Involved in active transport of urea.
What are the official names of this protein?
Probable urea active transporter 2.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: YBHG_SALPK
Sequence: MKKPVVIGLAIAAIVAVIAGGTWWYQSRQDDGLTLYGNVDIRTVNISFRVGGRLASLNVDEGDAIKAGQVLGELDHAPYENALMQAKAGVSVAQAQYDLMLAGYRDEEIAQAAAAVRQAQAAYDYAQNFYNRQQGLWKSRTISANDLENARSSRDQAQATLKSAQDKLSQYRTGNREQDIAQAKASLEQAKAQLAQAQLDLQDTTLIAPANGTLLTRAVEPGSMLNAGSTVLTLSLTRPVWVRAYVDERNLSQTQPGRDILLYTDGRPDKPYHGKIGFVSPTAEFTPKTVETPDLRTDLVYRLRIIVTDADDALRQGMPVTVKFNDEVRHE
What are the official names of this protein?
UPF0194 membrane protein YbhG.
What is the protein family that this protein belongs to?
Belongs to the UPF0194 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: TSAD_HYDCU
Sequence: MQTTHSNPSSPSLTLGIETSCDETGIALYHSEKGLIAHTLYSQIKLHAEYGGVVPELASRDHIRKITPLIQETLKKGQVSAKDITGIAYTAGPGLMGALLSGASVARSLAFAWQIPAIAIHHMEGHLLAPMLEETQPEFPFVCLLVSGGHTMIIRVDGIGRYKLLGDTLDDAAGEAFDKTAKMLGLGYPGGPEVSKLALHGQTDRYKFPRPMVDRPGLDMSFSGLKTFTLNTWLKAKESGDDSEQTKADICRAFEVAVADTLSIKCKRALEQEGLNRLVVSGGVSANREIRAKLDALMAKRKGSAFYPRLEFCTDNGAMIAYAGSKRLEAGQFSDLNFACQPRWDLESLEPIDPIEVV
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUT_BDEBA
Sequence: MQKLAVKIKKLENFHGDLPQYQSLGASGFDVRAQLAGPVVLNPGERAMIPTGLSFEIPLGYEIQARPRSGWAAKSGLTVLNTPGTIDADYRGEVKIIVINLGNEAVTINDQERCAQLVLAPVIQAQFELVNELSDTERGAGGFGSTGRA
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: MIAB_XANC8
Sequence: MPGTSVSDLPTTATAVDAPALLPLPVGRPQAPALVRGKLYIKTHGCQMNEYDSAKMADVLAASEGLELTDNPEDADVVLVNTCSIREKAQEKVFSQLGRWKALKAGGKPVIIGVGGCVASQEGEAIVKRAPYVDLVFGPQTLHRLPELIRARRESGKSQVDISFPEIEKFDRLPEPRADGPSAFVSIMEGCSKYCSFCVVPYTRGEEVSRPFEDVLVEVAQLAAQGVREINLLGQNVNAYRGAYGADAGEPAQYADLGLLIRTIAQIDGIGRIRFTTSHPLEFSDSLVDAYRDVPQLANYLHLPVQAGSDRILSAMKRGYTALEFKSKIRKLRAVRPDISISSDFIVGFPGETDADFDKTMKLIEDVGFDQSFSFIYSRRPGTPASDLEDDTPDAVKQARLARLQAHINAHAAGISQRMVGSVQRVLVEGPSRRDANELTGKTENMRPVNFPGNPRLVGQFVDVLITEALSNSLRGRIQLDDSAA
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_KORVE
Sequence: MARQVPLERCRNIGIMAHIDAGKTTTTERVLFYTGRTHRIGEVHEGTATMDWMAQEQERGITITSAATTCTWRDERINIIDTPGHVDFTAEVERSLRVLDGAVAVFDAVHGVEPQSETVWRQADKYSVPRICFINKIDKMGADFEHAIDTIRKRLNAKPVAIQYPIGLEDKFKGVIDLFKMKALVWHDEAMGSQYDVEEIPAELLKKAQAFHNLMVETIAECDDELMAKYIEGEEMTAAELQAGLRRATIAMKVFPVTVGTAFKNKGVQTLLDAVVDYLPSPLDIPPVTGKNPDTGLEEQRSADDKQPFAALAFKIMTDPFVGQLTFIRVYSGQLKTGDSVYNSSKGRTERIGRLLKMHANKREEIGEIMAGDICAVVGLKTITTGDTISDEKHPLVLESIEFPTPVISVAVEPKTKSDQEKMGVALNKLAQEDPTFRVSTDPDSGQTIIAGMGELHLEILVDRMMREFHVQANVGKPQVAYRETIRKEAQAEGKYIRQTGGSGQYGHCKIRVGPNEPGKGYEFINDIVGGTIPKEFIKPIDQGIKEALEGGVLAGYEMVDVKVTLYDGSYHDVDSNEMAFKIAGSMAFKEAARKASPVLLEPVMSVEVVVPEEYMGVIIGDLNSRRGRIEGLEHRAGSQVVKAMVPLAEMFGYVNSMRSNTQGRATFSMHFAHYEEAPRSVAEEIVAKVQGKPAAR
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP03_EHV2
Sequence: MDSTSKRSSFKRARGGRATVYFYVPTWQHGPGGQPPVSSFAFSLVNEVGFGVLFDYGCAGTGGATAGRAAAAVDPGVASEAFMEILRTVLPGHRVGAVSELPAGLGSYLTSGDDGAGGPCTLSRDVAPMMQALLEHLIRGQQQLRRPLVGDAGEGAGRGPGEGEATTPIPKILAVSFFHTLWSLHSIKQHHAYMLCNQLSSPASFCRTPGYLGFTPLGDPGERPDLKFARVPVPALAHPKADALAKLPEMFREHDSDVLTGTHRGAIKIRNPFNGLLGYLCRLYAPTSRVFIDRDVFSSNGKPDYFGVVYQVGGISTGASELDLLYSEAGTFGWGNVLGLHLGVVGSGEDPFALQEYLESHMLAQRCSGAPTLLGFVRVMDGSAAPPGMGPASRPHSFTGATRASIISPKACLSPVRGGGASVFMLGDFFQRPQRAGGAYASHDSGRRLASILAAVQTFINVAGGRAVLSTCQSRLEGTMHAKIAAACGVMGLKTYTSLLPEEAVSELSHFSPGNASMNRSILLSKFLNVEAQVVLLTVVNTPRNRQILEGVFKTFGCRVSLLGHLARAKKIVLYDDRSPDYCQGGPRYLCFKMHKPRYALPIDRWCGTASYRPTAPSRVPYNSSDAGPPSDAREVLLGILRHPTVGCKNYIVKHVDRCASGRVAQQCGVGPLDLPVADYSMVVVEPSAGPPSSMEPWTWETPQVPDDCFLIHEDGVSGVCSALGEKNSVFPFYPEAGAKMAIAESVLSLALAPIARIEDVTVNLSLAWPHLKGAQGEVFTLLTRCKRFCEDAGVSCNVTSCASSRRAGGGDPPEGGADIKSFVASAFAYTPCAFWKLTPDLKEARSVILFLPASPGKHAFASVYQQVRGQKKYTGSPVNISGAYLGKLARAVLHLRAKRLAVSGHDVGDGGLWAALAEMAMAGMRSLDVEVPVRLDGDPMGFLTSETPGVALEVPLSSASAAVEYLRSKYILCYRVGVTGHKTCERMFRITRGDQVLLECEQEEVGEAWRSHSVRMERYGPCFNRHAYGEGPYEREREAFLAYTPFRILNRPNKKHRVAVLLLPGCPYPLAALDALRDSGFDALAVSHLDLAHVLTDEVCGLFVAGVDNTSDTKTSDALTSALVHSRNPGVIRDFLSRKDTFSLGVGSMACRILFDGDMAVSPALQSRDIRCVPAVSCKFESRWLNVFINQSTPAVAFRTLRGSLLPCWAQGTHLGFGAPSPECLDRLVASGQAASMFYGSDVASGPAMAYPANPTETLPVAGICSRDGRHLVLLHDITASYYLWQWPHVPKSNIPIAVSPWKQVFYDLHAWVTAHSH
What are the official names of this protein?
Probable membrane antigen 3, Tegument protein.
What are the subcellular locations of this protein?
Virion tegument.