PharMolix/UniProtQA huggingface dataset:
Protein: INUE_ASPNG
Sequence: MARLLKAVTVCALAGIAHAFNYDQPYRGQYHFSPQKNWMNDPNGLLYHNGTYHLFFQYNPGGIEWGNISWGHATSEDLTHWEEQPVALLARGYGSDVTEMYFSGSAVADVNNTSGFGKDGKTPLVAMYTSYYPVAQTLPSGQTVQEDQQSQSIAYSLDDGLTWTTYDAANPVIPNPPQPYQAQYQNFRDPFVFWHDESHKWVVVTSIAELHKLAIYTSDNLKDWKLVSEFGPYNAQGGVWECPGLFKLPLDGGSSTKWVITSGLNPGGPPGTVGSGTQYFVGEFDGTTFTPDADTVYPGNSTANWMDWGPDFYAAAGYNGLSIKDHVHIGWMNNWQYGANIPTYPWRSAMAIPRHLALKTINNKTTLVQQPQEAWSSISSKHPLYSRTYSTFSEGSTNASTTGETFRVDLSFSATSKASTFAIALRASANFTEQTLAGYDFAKQQIFLDRTKSGDVSFDNTFASVYHGPLVPDSTGMVRLSIFVDRSSVEVFGGQGETTLTAQIFPSNDAVHARLVSTGGATEDVRVDVHNITSTWN
What is the function of this protein?
Exo-inulinase involved in utilization of the plant storage polymer inulin, consisting of fructooligosaccharides with a degree of polymerization (DP) value from 2 to 60.  Splits off terminal fructose units successively from the non-reducing end of the inulin molecule, and also hydrolyze sucrose and raffinose.
What are the official names of this protein?
Extracellular exo-inulinase inuE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 32 family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y2265_BACCZ
Sequence: MLGIDVKKTKEELIISWQLAEITIPLRDVIEVTEDATYAGVEETSAIRIGTAYGTTDRILIKTVKQNYVLFTTNKVSILNAINAKN
What are the official names of this protein?
UPF0457 protein BCE33L2265.
What is the protein family that this protein belongs to?
Belongs to the UPF0457 family.
Protein: ALR_LISIN
Sequence: MVTGWHRPTWIEIDRAAIRENIKNEQNKLPDKVALWAVVKANAYGHGIIETAKIAKEAGAKGFCVAILDEALALREAGFRNEFILVLGATRKEDANLAAKNNISVTVFREDWLDDLTLEAPLRIHLKVDSGMGRLGIRSREEAQRIETTIAIDHQMILEGIYTHFATADQLETSYFEQQLAKFQAILSSLTTRPTFVHTANSAASLLQPQIDFDAIRFGISMYGLTPSTEIKNSLPFELKPALALYTEMVHVKELAPGDSVSYGATYTATEKEWVATLPIGYADGLIRHYSGFHVLVEGERAPIIGRICMDQTIIKLPREFQTGTKVTIIGSDHGNKVTADDAAEYLGTINYEVTCLLTERIPRKYIN
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: DCL2_PHANO
Sequence: MADSHDAPFRLRSYQAEMVEESMQSNIICVMDTGSGKTHIAIDRTRAELEICRPDKIVWFLAPTVTLCEQQFAVFKSNLPGYGIQLLSGKDNLDHWTDQGVWDDVLLNIRIVLSTHQVLLDALSHGFVKMRNLSLLIFDEAHHCSLKHPAHRIMSDFYKPRIGTELPRILGLSASPIKTAKVTSEDLQQIERNLCATVKTPKLHRSELLRYVHRPHLMRIDYPVEPQDLQSNMLSFLKSAYTNYDLQKDPWVSELLQQRQQGHDVTKNIHKVFIGGKTYCRDQLRSLALKAEAMSQELGMSVMDWYLRGCITQFSKMVHMSDSQLLDWSADEKRHLLEILRTLPSIDLNSHDIPPMSLGSMSHKLQLLIKFLVAEAKHDPEFTCLVFVEQRVWVACIAEVLAIHPETRDLLRVGTFVGESENSKRKANIASISEPRNQQATLENFRAGKLNLILATSVLEEGIDVSSCHLVVCFESPKNLKSFVQRRGRARKEESKYVIFVPQAGRRRDPESWQSLEEGMKAAYLDDLRQVKLATEKEQQSETGHRNFEVKSTGALLTLDNASQHLHHFCSILGAGPYIDNRPQFEFTEIRPGVITARVILPLTVDPEVRTACALDTWATEKMAKQDAAFEAYKALYVAGLVNDNLLPARQEADDELSELQIPDHRPSLVPVSPTLDPWPLFARHQQQNPHVYYRTRLTLHTVDDKPKHLILLTPKILPDIPELLLYWNSSTKLKIESSWLHDVVLNDEEISELKSVTYKILYSVFHNRMELNRRDFVWLVAPCDESGLLDSRIWLSEWRQHTCLATELIAQNSDWSLWGLVNQKGDARKYTPRSTSMNNQLWLLQLMQLPKRRDFLHPVLESANINDAYTKTDEMAAKDCIVDPVPAPYSVFALLLPSILHRFGMAIIAETLRTTLLGPVALDSAHSLLLTRALKSSAADGNDNYQRLEFLGDCILKFIATVHLMAANPKWPESHLTAKKGRIVSNGFLARATIAAGLDRFMITKSFTGAKWAPRYAGDLLAETGPAVKEERSSKLIADIIESLIGACYTVGGFEKAVLCVQTLLPLEPWISVPAANSILHEAAPAEADLMGLDVLETLIGYTFKKKPLLLEALTHASFSGPHVHCSYERLEFLGDAVLDYIISKRLHAHSPELSHQKMHAIRTATVNASFLAFRLFETTIDEETINKTSMRPESQKRAIWQFLRSGSPSLNANRDNALRQHEQVRDEIIIGLNEAARFPWHLFALTDPPKFLSDMVESVIGAVYIDSLGDILTCEAIVRRLGILDCLDHILCNGVDCLHPKERLGHLAVDKGVQYARVGMNTEPNEGDKMYKCQVKVGGEDVGDVAEGLKRLNAETVAAWKAVGVLESRKDSAIEIVSDVEEFFDADDGGGISLDDP
What is the function of this protein?
Dicer-like endonuclease involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway.  Produces 21 to 25 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs leading to sequence-specific suppression of gene expression, called post-transcriptional gene silencing (PTGS).  Part of a broad host defense response against viral infection and transposons (By similarity).
What are the official names of this protein?
Dicer-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the helicase family. Dicer subfamily.
Protein: RL23_COXB1
Sequence: MNEERLFKILLAPHISEKGALTTGQYVFEVMPDATKPEIKRAVEKQFNVTVKSVRTCNVKGKTTRFRQVRGRRKNWKKAYVMLAPGSEIDIAAGE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: Y2739_SHESR
Sequence: MLGWTLMFLVVAIIAGLFGFTGIAGAAAGIAKIIFFLFIVLLVISLLVNALKGKAPRA
What are the official names of this protein?
UPF0391 membrane protein Shewmr7_2739.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PNP_PROMH
Sequence: MLNPTVRKFQYGQHTVTLETGMMARQATAAVMVDMDGTAVFVTVVAKKKVKEGQDFFPLTVNYQERSYAAGRIPGSFFRREGRPGEGETLIARLIDRPLRPLFPEGFLNEIQVVATVVSVNPQVNPDIVAMIGASAALSLSGVPFNGPIGGARVGFIDGQYVLNPTVDELKISKLDLVVAGTAGAVLMVESEADLLSEEQMLGAVVFGHEQQQVVIENINALVAEVGKEKWDWAPEPINQSLHDRIAQLAQTRIGDAYRITEKQERYEQIDAIRDEVISTLLAEDESLDEGEIIEIFSGLEKKIVRARVLAGEPRIDGREKDMVRALDIRTGLLPRTHGSALFTRGETQALVTATLGTARDAQTIDDIMGEHTDTFLLHYNFPPYSVGETGMMGSPKRREIGHGRLAKRGVLAVMPTIEEFPYTVRVVSEITESNGSSSMASVCGASLALMDAGVPIKESVAGIAMGLVKEGENFVVLSDILGDEDHLGDMDFKVAGSRNGVSALQMDIKIEGITREIMQVALNQAKSARLHILGVMESAISQPRAEISEFAPRIHTIKINADKIKDVIGKGGSVIRALTEETGTTIEIEDDGTVKIAATSGEQAKQAIARIEEITAEVEVGRIYNGKVTRIVDFGAFVAIGGGKEGLVHISQIADKRVEKVSDYLTMGQEVPVKVLEIDRQGRIRLSMKEAQATQQEAAETSSEDPAN
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS9_DEHMB
Sequence: MVEKNTYFIGVGRRKTAVATVKLMSGNGVIVIDGKPIEERFTRIQERNVILNPMMVTDTMGKFNAVIKVLGGGVTGQSGAIAHGIARALEKTDEKLRATLKSNGLLTRDDRTKERKKPGLKRARKAPQYTKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: CHO_ECOLI
Sequence: MVRRLTSPRLEFEAAAIYEYPEHLRSFLNDLPTRPGVYLFHGESDTMPLYIGKSVNIRSRVLSHLRTPDEAAMLRQSRRISWICTAGEIGALLLEARLIKEQQPLFNKRLRRNRQLCALQLNEKRVDVVYAKEVDFSRAPNLFGLFANRRAALQALQTIADEQKLCYGLLGLEPLSRGRACFRSALKRCAGACCGKESHEEHALRLRQSLERLRVVCWPWQGAVALKEQHPEMTQYHIIQNWLWLGAVNSLEEATTLIRTPAGFDHDGYKILCKPLLSGNYEITELDPANDQRAS
What is the function of this protein?
Incises the DNA at the 3' side of a lesion during nucleotide excision repair.  Incises the DNA farther away from the lesion than UvrC.  Not able to incise the 5' site of a lesion.  In vitro, the incision activity of Cho is UvrA and UvrB dependent.  When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA.  Then UvrC makes the 5' incision.  The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair.
What are the official names of this protein?
Excinuclease cho, Endonuclease cho, UvrC homolog protein.
Protein: TBB1_CAEBR
Sequence: MREIVHIQAGQCGNQIGSKFWEVISDEHGIDPTGQYVGDSDLQLERINVYYNEAGSNKYVPRAVLVDLEPGTMDSVRSGPFGQLFRPDNYVFGQSGAGNNWAKGHYTEGAELVDNVLDVVRKEAESTDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETFCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRSNQQYRAITVPELTQQCFDAKNMMAACDPRHGRYLTAAAIFRGRMSMKEVDEQMLNIQNKNSSYFVDWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQEAAADEDAAEAFDGE
What is the function of this protein?
Mec-7 beta-tubulin is required for the production of 15-protofilament microtubules.
What are the official names of this protein?
Tubulin beta-1 chain, Beta-1-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: TM207_MOUSE
Sequence: MSTSSPFRVASKIVTAGCLCLPLFQRVLSDLSCEENEMCVNYDERYPDGWYIWFFLLIFLVVLLCGVVLFCLQCWLKRCGINPPRRTMAVFAVGDLDPVYGAEMAGSPTSGICHPTQNTELCSAPCFGALGPPPPYEEILKAN
What are the official names of this protein?
Transmembrane protein 207.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: CCSA_PROMT
Sequence: MVDFQLNNFSFDPVVSLGFAAFLFLLMALPISFWAVAGSSDSSKARFLVAISNLFLTSQLILRWWQSGHFPISNLYESLCFLTWGCTLAQLFLERAWRSPIVSAVATPVSLLSIGFASFVLPENLQSSAPLVPALRSSWLVMHVSVIMCSYAALLIGSILSFGVFLVDGKKQFNIRNSSFGSGSFRQSSELYLDERNENLNSIQPIEFTNAEQLDSLSYRSITAGFLLLTVGLISGAVWANEAWGSWWSWDPKETWALICWLVYAAYLHTRITRGWQGKKPAILAIAGFFVIIVCYIGVNLLGVGLHSYGWFFDA
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: HISX_VIBCH
Sequence: MRTVVWQSLSEAQQESILERPAITEGANITAAVAQVIAKVRSEGDAALFELTEKFDRVKPASLRVSREEMDAAAARLSETMKQALEQAYNNISKFHKAQKAQPIKVETMPGVVCEQVTRPINKVGLYIPGGSAPLPSTVLMLGVPAQIAGCRKVVLCSPPPIADEILYVAKLCNIDEVYNLGGGQAIAAMAYGTETVTKVDKIFGPGNAYVTEAKRQVSNDFRGAAIDMPAGPSEVLVIADETADANFIAADLLSQAEHGPDSQVVLVTPSPVLADQVTDAVQKQLKVLSRASIAEKALASSLIIIAESLTQAVSISNYYGPEHLIVQTRNPRELVPLLDNAGSIFLGDWSPESVGDYASGTNHVLPTYGYTRTYSSLGLADFSKRMTVQELTADGLQLLAPTVVTMAEAEGLDAHKRAVTIRVEKLQKAQ
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: IPYR_DROME
Sequence: MLAKITRSSFYASRAVGRLSGSIPTSPAALASNCRYIQIERKRTKSHEMALYETVEKGAKNSPSYSLYFKNKCGNVISPMHDIPLYANEEKTIYNMVVEVPRWTNAKMEISLKTPMNPIKQDIKKGKLRFVANCFPHKGYIWNYGALPQTWENPDHIEPSTGCKGDNDPIDVIEIGYRVAKRGDVLKVKVLGTIALIDEGETDWKIIAIDVNDPLASKVNDIADVDQYFPGLLRATVEWFKIYKIPDGKPENQFAFNGDAKNADFANTIIAETHKFWQNLVHQSPASGSISTTNITNRNSEHVIPKEEAEKILAEAPDGGQVEEVSDTVDTWHFIHLK
What is the function of this protein?
Component of NURF (nucleosome remodeling factor), a complex which catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin (PubMed:9784495).  NURF is required for homeotic gene expression, proper larval blood cell development, normal male X chromosome morphology, ecdysteroid signaling and metamorphosis (PubMed:9784495, PubMed:8521501).  Inorganic pyrophosphatase (PPase), hydrolyzes inorganic pyrophosphate to inorganic phosphate, essential for driving critical biosynthetic reactions including transcription, replication, and DNA repair (PubMed:9784495).
What are the official names of this protein?
Inorganic pyrophosphatase, Nucleosome-remodeling factor 38 kDa subunit, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MSHD_MYCSS
Sequence: MTSIDWRSALTDDEQGSIRDIVAAATRHDGVAPVGDQVLRELPADRTRHLVAVDPDAGAVVGYLNLAPASDTAPPMAELVVHPDFRRRGTGAAMARAGLAEGGTHARIWAHGNLEAARATARTLGLQVVRELLQMRRPLTDLPPVTVADGVRLATYSGPGDDPELLRINNSAFAWHPEQGGWTDADIAERRAEAWFDPAGLFMAFDDASGKLLGFHWTKVHGPDLGEVYVVGVDPAAQGRGLGATLTLTGLHHLAERLSNSPQPTVMLYVEADNGAAVKTYRRLGFDVSSVDAAYAAVAD
What is the function of this protein?
Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
What are the official names of this protein?
Mycothiol acetyltransferase, MSH acetyltransferase, Mycothiol synthase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. MshD subfamily.
Protein: SYN_STAAC
Sequence: MKTTIKQAKDHLNQDVTIGAWLTNKRSSGKIAFLQLRDGTGFMQGVVVKSEVDEEVFKLAKEITQESSLYVTGTITEDNRSDLGYEMQVKSIEVISEAHDYPITPKNHGTEFLMDHRHLWLRSKKQHAVMKIRNEVIRATYEFFNKDGFTKVDPPILTASAPEGTSELFHTKYFDQDAFLSQSGQLYLEAAAMAHGKVFSFGPTFRAEKSKTRRHLIEFWMIEGEMAFTNHAESLEIQEQYVTHVVKSVLENCKLELKILERDTSKLEKVATPFPRISYDDAIEFLKAEGFDDIEWGEDFGAPHETAIANHYDLPVFITNYPTKIKPFYMQPNPENEETVLCADLIAPEGYGEIIGGSERVDDLELLEQRVKEHGLDEEAYSYYLDLRRYGSVPHCGFGLGLERTVAWISGVEHVRETAPFPRLLNRLYP
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOQT_BACSU
Sequence: MELILDCFVNWSFDKIMDYILIAGLYFVFKSKSKQNYPDHFEEKRRHRN
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YoqT.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: ERLL2_ARATH
Sequence: MASKNSASLALFFALNILFFTLTAGTNCRCNPSPKPRPLPNPKVPSPKVPTPSVPSPYVPTPSVPSPSVPTPSVPSPSVPSPNPTPVIPPRTPGSSGNCPIDALRLGVCANVLSGLLNVQLGQPSPQPCCSLIQGLVDLDAAVCLCTALRANVLGINLNVPISLSVLLNVCNRRLPSNFQCA
What is the function of this protein?
Probable lipid transfer protein (LTP).  May improve freezing survival.  Seems to control the flowering process and lignin synthesis.  Confers resistance to Botrytis cinerea.
What are the official names of this protein?
pEARLI1-like lipid transfer protein 2.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family. PEARLI1 subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: DGGGP_METMJ
Sequence: MSVSAFIRITRPHNAVVAGLTALIGYLIATGTLTPPSLLLAVIVALITAGGNVINDVRDVEIDRINRPDRPIPAGDISLAGARAYAAALFVGGIAIATLTTTLCLAIAIINSVILIVYAVRLKRTPVLGNVAVAYLAGSVFLFGGAFAGIEGLVRNLSLAAITFLATIARELLKDAEDVDGDAAGGARTLPMIVGVRKTGIFAFACACGAVAASLLPFGDWWGLFYLAGIAVVDLVILFGAFRGLSCTTPGCVRESNATSILRAGMFAALAVFAIAAVI
What is the function of this protein?
Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP).  This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
Digeranylgeranylglyceryl phosphate synthase, DGGGP synthase, DGGGPS, (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase, Geranylgeranylglycerol-phosphate geranylgeranyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. DGGGP synthase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: OXND1_XENTR
Sequence: MALVAGSAAYQVLRGVTGTFPTQSATLLARAPALCARTLNRRRMSSRRQTDHLERTANTFRQEIISPAKVCEITNESATVKRVRLAIANREFTFKAGQWVDFFIPGVPKVGGFSICSCPGLLETEGVLELAVKYNLHPPAHWIHSQCTLGSEVAVRVGGEFCFDPQPSDLPLDLVLIAGGVGINPLFSILLHVADLHKTHEMTGRGFQMGNVKLYYCAKNTGELLFKRNILDLVKSFPGKITCSFHVTQQSSPVCVELQPFITEGRITEKDLASYVSTDQLCYICGPPPMIESTCKQLESLHVPKEQILFEKWW
What are the official names of this protein?
Oxidoreductase NAD-binding domain-containing protein 1.
Protein: PYRE_PROA2
Sequence: MSSPALLDVFTSTGALLNGHFKLTSGLHSNTYFQCAKVLQHPEHLAEICRHIADHFKKNNIDTVISPAIGGIVVGTEVGRQLGVKTIFAERKDGAMSLRRGFSIEPGEKILVIEDVITTGGSVAEVIEIVKSYGGEIVGVGTVVDRSNGKVTLADNQYSLLSLEVRSYEPADCPLCKDNIPLESPGSRASKNN
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: LLDD_VIBCH
Sequence: MIISASTDYRAAAKAKLPPFLFHYIDGGSYGEHTLRRNTDDLADIALRQRVLSDMSELSLETELFGEKMALPIALSPVGLTGMYARRGEVQAAQAAEAKGIPFTLSTVSVCPIEEVAPSIHRPIWFQLYVLKDRGFMKNVLERAKAAGVKNLVFTVDMPVPGARYRDMHSGMSGPNAAMRRVLQAMAHPSWAWDVGLLGKPHDLGNISKYRGSPTKLEDYIGWLGANFDPSISWKDLEWIRDFWDGPMIIKGILDTEDAKDAVRFGADGIVVSNHGGRQLDGVLSTVQALPAIADAVKGDLKILVDSGIRTGLDVVRMLALGADCTMLGRSFIYALAAQGRAGVENLLDLYEKEMRVAMTLTGAKSIAELSRDSLVKR
What is the function of this protein?
Catalyzes the conversion of L-lactate to pyruvate.  Is coupled to the respiratory chain.
What are the official names of this protein?
L-lactate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS14_CORGB
Sequence: MAKKSKIAKNEKRKEIVARYAERRAELKAIIRNPNTSDEDRLDAQFELNSQPRDAAAVRVRNRDSHDGRPRGYLRKFGLSRVRMREMAHRGELPGVRKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: PADI4_HUMAN
Sequence: MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP
What is the function of this protein?
Catalyzes the citrullination/deimination of arginine residues of proteins such as histones, thereby playing a key role in histone code and regulation of stem cell maintenance (PubMed:15339660, PubMed:15345777, PubMed:16567635, PubMed:21245532).  Citrullinates histone H1 at 'Arg-54' (to form H1R54ci), histone H3 at 'Arg-2', 'Arg-8', 'Arg-17' and/or 'Arg-26' (to form H3R2ci, H3R8ci, H3R17ci, H3R26ci, respectively) and histone H4 at 'Arg-3' (to form H4R3ci) (PubMed:15339660, PubMed:15345777, PubMed:16567635, PubMed:21245532).  Acts as a key regulator of stem cell maintenance by mediating citrullination of histone H1: citrullination of 'Arg-54' of histone H1 (H1R54ci) results in H1 displacement from chromatin and global chromatin decondensation, thereby promoting pluripotency and stem cell maintenance (PubMed:15339660, PubMed:15345777, PubMed:16567635, PubMed:21245532).  Promotes profound chromatin decondensation during the innate immune response to infection in neutrophils by mediating formation of H1R54ci (PubMed:18209087).  Required for the formation of neutrophil extracellular traps (NETs); NETs are mainly composed of DNA fibers and are released by neutrophils to bind pathogens during inflammation (By similarity).  Citrullination of histone H3 prevents their methylation by CARM1 and HRMT1L2/PRMT1 and represses transcription (PubMed:15345777).  Citrullinates EP300/P300 at 'Arg-2142', which favors its interaction with NCOA2/GRIP1 (PubMed:15731352).
What are the official names of this protein?
Protein-arginine deiminase type-4, HL-60 PAD, Peptidylarginine deiminase IV, Protein-arginine deiminase type IV.
What is the protein family that this protein belongs to?
Belongs to the protein arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasmic granule. Note=Cytoplasmic granules of eosinophils and neutrophils.
Protein: DEDA_BORBU
Sequence: MTKMYINTIIEYIDSNIAYSPIVFFSLLILAGLNVPISEDAIVLMGGILSSRKNEYTILIFLGIFWGAYLGDIISFYIGKLMGNKLFKNKKDNNLLDKINYYYGQYGVLTLFIGRFIPFGVRNAIFMSAGMGNMKSNLFIVSDFFATLLSIVVYFTLSFKLGQSFEIIFSKIKIIIFAIFIAVIATTIIIYVIKKNKKVDKNLK
What is the function of this protein?
Required for proper cell division and envelope integrity.
What are the official names of this protein?
Inner membrane protein BB_0250.
What is the protein family that this protein belongs to?
Belongs to the DedA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: END4_STAA9
Sequence: MLLGSHVSMSGKKMLEGSAIEAYEYGETTFMIYTGAPQNTRRKSIEDLNITKGHEVMEKYGLSNIVVHAPYIINIANTTKPETFNLGVDFLQQEIERTQAIGAKDIVLHPGAHVGAGVDAGINKIIEGLNEVLTNDNNVRIALETMAGKGTEIGRSFEELARIIDGVHNNERLSVCFDTCHTHDAGYNVKEDFDGVLNEFDKIIGVDRIKVVHVNDSKNDRGAQKDRHENIGFGYIGFDALNYIVHHDSFKDIPKILETPYVGEDKKNKKPPYKLEIEMLKQQQFDPELKNKVMQQ
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: ISPG_ORYSJ
Sequence: MATGVAPAPLPHVRVRDGGIGFTRSVDFAKILSVPATLRVGSSRGRVLVAKSSSTGSDTMELEPSSEGSPLLVPRQKYCESIYETRRRKTRTVMVGNVPLGSDHPIRIQTMTTSDTKDVAKTVEEVMRIADKGADFVRITVQGRKEADACFEIKNTLVQKNYNIPLVADIHFAPTVALRVAECFDKIRVNPGNFADRRAQFEQLEYTEDDYQKELEHIEKVFSPLVEKCKQYGRAMRIGTNHGSLSDRIMSYYGDSPRGMVESALEFARICRKLDFHNFVFSMKASNPVIMVQAYRLLVAEMYNLGWDYPLHLGVTEAGEGEDGRMKSAIGIGTLLMDGLGDTIRVSLTEPPEEEIDPCRRLANLGTHAADLQIGVAPFEEKHRRYFDFQRRSGQLPLQKEGEEVDYRGVLHRDGSVLMSVSLDQLKAPELLYRSLAAKLVVGMPFKDLATVDSILLRELPPVEDAQARLALKRLVDISMGVLTPLSEQLTKPLPHAIALVNVDELSSGAHKLLPEGTRLAVTLRGDESYEQLDLLKGVDDITMLLHSVPYGEEKTGRVHAARRLFEYLETNGLNFPVIHHIEFPKSVNRDDLVIGAGANVGALLVDGLGDGVLLEAADQEFEFLRDTSFNLLQGCRMRNTKTEYVSCPSCGRTLFDLQEVSAQIREKTSHLPGVSIAIMGCIVNGPGEMADADFGYVGGAPGKIDLYVGKTVVQRGIAMEGATDALIQLIKDHGRWVDPPVEE
What is the function of this protein?
Enzyme of the plastid non-mevalonate pathway for isoprenoid biosynthesis that converts 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.  Is essential for chloroplast development (By similarity).
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin), chloroplastic, 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: TARS_STAAW
Sequence: MMKFSVIVPTYNSEKYITELLNSLAKQDFPKTEFEVVVVDDCSTDQTLQIVEKYRNKLNLKVSQLETNSGGPGKPRNVALKQAEGEFVLFVDSDDYINKETLKDAAAFIDEHHSDVLLIKMKGVNGRGVPQSMFKETAPEVTLLNSRIIYTLSPTKIYRTTLLKDNDIYFPEELKSAEDQLFTMKAYLNANRISVLSDKAYYYATKREGEHMSSAYVSPEDFYEVMRLIAVEILNADLEEAHKDQILAEFLNRHFSFSRTNGFSLKVKLEDQPQWINALGDFIQAVPERVDALVMSKLRPLLHYARAKDIDNYRTVEESYRQGQYYRFDIVDGKLNIQFNEGEPYFEGIDIAKPKVKMTAFKFDNHKIVTELTLNEFMIGEGHYDVRLKLHSRNKKHTMYVPLSVNANKQYRFNIMLEDIKAYLPKEKIWDVFLEVQIGTEVFEVRVGNQRNKYAYTAETSALIHLNNDFYRLTPYFTKDFNNISLYFTAITLTDSISLKLKGKNKIILTGLDRGYVFEEGMASVVLKDDMIMGMLSQTSENEVEILLSKDIKKRDFKNIVKLNTAHMTYSLK
What is the function of this protein?
Attaches beta-O-GlcNAc (beta-O-N-acetyl-D-glucosamine) residues to the C4 position of poly(RboP)-wall teichoic acids (WTAs).  Prefers UDP-GlcNAc as a donor substrate and is specific for poly(ribitol phosphate) WTAs.  Can also use UDP-Glc and UDP-GalNAc, but not UDP-galactose or UDP-glucuronic acid.  Mediates beta-lactam resistance in methicillin resistant Staphylococcus aureus (MRSA) strains.
What are the official names of this protein?
Poly(ribitol-phosphate) beta-N-acetylglucosaminyltransferase TarS, Beta-O-GlcNAc transferase, Beta-O-GlcNAc-WTA transferase, WTA glycosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.