PharMolix/UniProtQA huggingface dataset:
Protein: PPNP_ALBFT
Sequence: MTTTHIDQVSVSTQASVYFDGKCISHGVTLADGTKKSVGVILPATLTFNTGAPEVMECVAGSCDYKLPGSEVWLKSKPGDKFSIPGNTPFDIRVTEPYHYICHFG
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: RL18_CORJK
Sequence: MSNTAQNEKRLPVGKDISTRRRTARARRHFRIRKTLSGTPETPRLVIHRTSRHMHAQVIDDVAGHTLVAASTMEADVRAMEGDKKARGAKVGQLIAERAKAAGIEAVVFDRAGYKYHGRVAALADAAREGGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RS16_HISS2
Sequence: MVTIRLSRGGSKKRPFYQIVVADSRSPRDGRFIERVGFFNPLASGNVERVRINLDRVNHWIGHGASLSDRVASLVKEAQKAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: GGA2B_HUMAN
Sequence: MDSEEEEEVPQPMPSIPEDLESQKAMVAFFNSAVASAEEEQARLCGQLKECTASAWLICWPRPRRNLRQQPQPQELGVIPCVGRPTRPCRGPWRSCGRVHRTVPEPEGSAEGGGVHQQAGPGQGRGEGEAAGAGVACGRLQQVA
What are the official names of this protein?
Putative golgin subfamily A member 2B, Golgin subfamily A member 2-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the GOLGA2 family.
Protein: TPX_OCEIH
Sequence: MSNVTFKNDPVTLLGAEKKVGDSAPDFTVLANDLSKKHLSDYKGKVKVISVVPSIDTGVCSEQTRRFNQEATNLENVQILTISMDLPFAQKRWCAANGIDRVDTLSDHREADFGQKYGVIIEELRLLSRAVFVVDENDKITYVEYLSEVSNHPDYEAVLSHLNK
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Thiol peroxidase, Tpx, Peroxiredoxin tpx, Prx, Thioredoxin peroxidase, Thioredoxin-dependent peroxiredoxin.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. Tpx subfamily.
Protein: SURE_BRUMB
Sequence: MRILLTNDDGIHAEGLAVLERIARKLSDDVWVVAPETDQSGLAHSLTLSEPLRLRQIDARHFALRGTPTDCVIMGVRHVLPGAPDLVLSGVNSGANMADDVTYSGTVAGAMEGTLLGVRAIALSQEYEYAGDRRIVPWETAEAHAPELIGRLMEAGWPEGVLLNLNFPNCAPEEVKGVRVTAQGKLSHDARLDERRDGRGFPYFWLHFGRGKAPVADDSDIAAIRSGCISVTPLHLDLTAHKVRAELGAALGVEA
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_MESH2
Sequence: MAKIVVGLSGGVDSAVSAYLLKKAGHNVIAVFMRNWDSSLNNDFLGKKNEKNFTICPQEQDWLDAKVVAKQLNIPIFRIDFIKEYWDEVFSDLILKYQSGLTPNPDILCNKNIKFKHFLDYAQKVHNADFIAMGHYAKTDNGNLYAGADSLKDQSYFLGQLSKSQLQKTIFPLGNLHKSEVRKIANELGLINAKKKDSTGICFIGERKFTDFLQNYIPAQPGNIIDISTKKVLGKHIGIMYFTIGQRKGFGLSGMKEPYFVVGHNLKEKILYVSPQSEKKWLESDSLMAKNANFLSENFRNLDNLSAKFRYRQEAIPIKIEKIQDNSFWISYQKYQAITPGQQVVIYHQNQVILAGEIALLFRNGKKLDYLD
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_HELHP
Sequence: MSEKQAHTRVIQGKVISQAGNKSIVILVERKVVHSKYRKIVKRFKKYTIHDENQSAKIGDVVSAIECKPISKTKAFRFKEIITAGVEL
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: GLDN_RAT
Sequence: MTRAAERGQGATGWGLRGALMAVALLSVLNAVGTVFVLYQWRELSAALRALEAQHGQEQREDSALRAFLAELSRAPARVPEPPQDPMSAARNKRSHGGEPASHIRAESQDMMMMMTYSMVPIRVMIDLCNSTQGICLTGPPGPPGPPGAGGLPGHNGSDGQPGLQGPKGEKGAVGKRGKMGLPGATGNPGEKGEKGDAGELGLPGNEGPPGQKGDKGDKGDVSNDVLLTGAKGDQGPPGPPGPPGPPGPPGSRRAKGPRQPNSFTNQCPGETCVIPNDDTLVGRADEKVNERHSPQTEPMITSIGNPAQVLKVKETFGTWLRESANRSDDRIWVTEHFSGIMVKEFEDLPALLNSSFTLLHLPHYFHGCGHAVYNNSLYYHKGGSNTIVRFEFGKETPQTLKLEDALYFDRKYLFANSKTYFNIAVDEKGLWIIYASSVDGSSILVAQLDERTFSVLRHINTTYPKSKAGNAFIAQGILYVTDTKDTRVTFAFDLLRGKQINANFGLRMSQSVLAMLSYNMRDQHLYSWEDGHLMLYPVHFSSTAPSQR
What is the function of this protein?
Ligand for NRCAM and NFASC/neurofascin that plays a role in the formation and maintenance of the nodes of Ranvier on myelinated axons.  Mediates interaction between Schwann cell microvilli and axons via its interactions with NRCAM and NFASC (PubMed:16039564).  Nodes of Ranvier contain clustered sodium channels that are crucial for the saltatory propagation of action potentials along myelinated axons.  During development, nodes of Ranvier are formed by the fusion of two heminodes.  Required for normal clustering of sodium channels at heminodes; not required for the formation of mature nodes with normal sodium channel clusters.  Required, together with NRCAM, for maintaining NFASC and sodium channel clusters at mature nodes of Ranvier (By similarity).
What are the official names of this protein?
Gliomedin.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Cell projection, axon. Note=Detected at the nodes of Ranvier (PubMed:16039564, PubMed:22009740). Detected at immature heminodes (PubMed:22009740). SUBCELLULAR LOCATION: [Gliomedin shedded ectodomain]: Secreted. Secreted, extracellular space, extracellular matrix. Note=Proteolytic processing gives rise to a soluble extracellular domain that is secreted. The gliomedin shedded ectodomain localizes to the nodes of Ranvier.
Protein: RS20_RHOJR
Sequence: MANIKSQVKRIRTNEAARLRNQSVKSSLRTAIRSFREAAAAGDKDKANELLVATSRKLDKAASKGVIHANQAANKKSALAQAINKI
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: Y135_MYCGE
Sequence: MQTLNYLVIILIIAGVISVLAFTPLVRKLKIRFYLIQVLAIVLFVYVFFGRQIIYLFPDVYGQNSQSSQNLDSLRLSRIFLLDLCPFFAVIAPVFVFLKQKKISGVLAVFGLFGALVTLFGELIFTPVNEQDIVNFIFVGTGNNQIYFMMHFLSLLVSLAIILWDNCFSLISFFYIHVFALIYFSYVALMVSVFKGQITGNTTGILASDWTNGEYKNVATFLNLSNSDPQLVFIVGFSLSYVAILLMTLFANIPTFMEMKKDKIFIKKENLIRKDLELLA
What are the official names of this protein?
Uncharacterized protein MG135.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: OTU1_DANRE
Sequence: MLRLRCKAKNGTHLMQGLTHQSCVQELKDKIEELTGIPCDVQKIMVGYPPSSLDLRNGEAHLKDYPIKSGDTLIVEEEKNKPKPPVQPTVTKGPSFEVTPVVERRVVPADNSCLFTSVNYVMEGGVYDPACASEMRGLIAQIVASDPTAYSEAVLGKTNEEYCTWIRRDDTWGGAIEVSILSKFYQCEICVVDTQTVRVDRFGEDAGYTKRVLLIYDGIHYDPLQKVLPGSDVPAQTVFSTVDDVILAQALELADEARRKRQFTDVNRFALRCMVCQTGLVGQKEAREHAKETGHTNFGEV
What is the function of this protein?
Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins.  May act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore.  Ubiquitin moieties on substrates may present a steric impediment to the threading process when the substrate is transferred to the VCP pore and threaded through VCP's axial channel.  Mediates deubiquitination of 'Lys-27'-, 'Lys-29'- and 'Lys-33'-linked polyubiquitin chains.  Also able to hydrolyze 'Lys-11'-linked ubiquitin chains.  Cleaves both polyubiquitin and di-ubiquitin.
What are the official names of this protein?
Ubiquitin thioesterase OTU1.
What are the subcellular locations of this protein?
Cytoplasm. Note=Recruited to damaged lysosomes decorated with K48-linked ubiquitin chains.
Protein: COAX_THIDA
Sequence: MSGCRILLDAGNSSLKWAVVEDGTWLARGRSDYSDLSAVEAELDAGSECFIASVASRVYEEKLAALLTAAGCSAVWLKSEAAFDDVTNDYRDPTQLGVDRWMGLVAARARRRAPTLVVSAGTAMTVDALSGDGSFLGGLIVPGVALMQRSLQQGTAGGAAAGGAWQAFPRCTADAAYSGIIAALCGAVEGQHVRLAAHEGISPACLITGGGAETLLPHLGVDAEHVPTLVLEGIERVARAGGRG
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAPA_CAMJJ
Sequence: MNRRDFIKNTAIASAASVAGLSVPSSMLGAQEDWKWDKAVCRFCGTGCGIMIARKDGKIVATKGDPAAPVNRGLNCIKGYFNAKIMYGEDRLVMPLLRMNEKGEFDKKGKFQQVSWQRAFDEMEKQFKKAYNELGVTGIGIFGSGQYTIQEGYAALKLAKAGFRTNNIDPNARHCMASAVVGFMQTFGVDEPSGCYDDIELTDTIITWGANMAEMHPILWSRVSDRKLSNLDKVKVVNLSTFSNRTSNIADIEIIFKPNTDLAIWNYIAREIVYNHPEAMDMKFIKDHCVFATGYADIGYGMRNNPNHPKFKESEKDTVEKENVITLDDEEAASLSYLGVKAGDKFEMKHQGVADKNWEISFEEFKKGLAPYTLEYTAKVAKGDDNESLEDFKKKLQELANLYIEKNRKVVSFWTMGFNQHTRGSWVNEQAYMVHFLLGKQAKPGSGAFSLTGQPSACGTAREVGTFSHRLPADMVVANPKHREISEKIWKVPAKTINPKPGSPYLNIMRDLEDGKIKFAWVQVNNPWQNTANANHWIAAAREMDNFIVVSDCYPGISAKVADLILPSAMIYEKWGAYGNAERRTQHWKQQVLPVGAAMSDTWQILEFAKRFKLKEVWKEQKVDNKLTLPSVLEEAKAMGYSEDDTLFDVLFANKEAKSFNPNDAIAKGFDNTDVKGDERKIQGSDGKEFTGYGFFVQKYLWEEYRKFGLGHGHDLADFDTYHKVRGLRWPVVNGKETQWRFNTKFDYYAKKAAPNSDFAFYGDFNKMLTNGDLIAPKDEKEHSIKNKAKIFFRPFMKAPERPSKEYPFWLATGRVLEHWHSGTMTMRVPELYRAVPEALCYMSEKDGEKLGLNQGDLVWVESRRGKVKARVDMRGRNKPPVGLVYVPWFDENVYINKVTLDATCPLSKQTDFKKCAVKIYKA
What is the function of this protein?
Catalytic subunit of the periplasmic nitrate reductase complex NapAB.  Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
What are the official names of this protein?
Periplasmic nitrate reductase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: NUOH_NITHX
Sequence: MAEFFAAPFWTDFLWPLIVMVAQSVLLLVVLLIAIAYILLADRKIWAAVQIRRGPNVVGPWGLLQSFADLLKFVLKEPIIPSGSNKGVFLLAPLVTCVLALAAWAVIPVNLNWVISDINVGILYIFAISSLSIYGIIMAGWSSNSKYPFLAALRSAAQMVSYEVSIGFVFITVLLCAGSLNLSAIVEAQHVRGLGSLIGLPWLTFLNWYWLPLLPMFVVFYVSALAETNRPPFDLVEAESELVAGFMVEYGSTPYLLFMLGEYVAITTMCAMGAILFMGGWLPPIDLPPFNWVPGVIWFSLKLFFMFFLFAMAKAIVPRYRYDQLMRLGWKVFLPLSLAMVVIVAGVLQFADIAPK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DGOA_ECOLI
Sequence: MQWQTKLPLIAILRGITPDEALAHVGAVIDAGFDAVEIPLNSPQWEQSIPAIVDAYGDKALIGAGTVLKPEQVDALARMGCQLIVTPNIHSEVIRRAVGYGMTVCPGCATATEAFTALEAGAQALKIFPSSAFGPQYIKALKAVLPSDIAVFAVGGVTPENLAQWIDAGCAGAGLGSDLYRAGQSVERTAQQAAAFVKAYREAVQ
What is the function of this protein?
Involved in the degradation of galactose via the DeLey-Doudoroff pathway.  Catalyzes the reversible, stereospecific retro-aldol cleavage of 2-keto-3-deoxy-6-phosphogalactonate (KDPGal) to pyruvate and D-glyceraldehyde-3-phosphate.  In the synthetic direction, it catalyzes the addition of pyruvate to electrophilic aldehydes with re-facial selectivity.  It can use a limited number of aldehyde substrates, including D-glyceraldehyde-3-phosphate (natural substrate), D-glyceraldehyde, glycolaldehyde, 2-pyridinecarboxaldehyde, D-ribose, D-erythrose and D-threose.  It efficiently catalyzes aldol addition only using pyruvate as the nucleophilic component and accepts both stereochemical configurations at C2 of the electrophile.
What are the official names of this protein?
2-dehydro-3-deoxy-6-phosphogalactonate aldolase, 2-oxo-3-deoxygalactonate 6-phosphate aldolase, 6-phospho-2-dehydro-3-deoxygalactonate aldolase, 6-phospho-2-keto-3-deoxygalactonate aldolase, KDPGal.
What is the protein family that this protein belongs to?
Belongs to the KHG/KDPG aldolase family.
Protein: AROE_HALMA
Sequence: MDVYGLIGNPVGHSLSPPMHEAGYEALGLDARYVTFEPPADAGAEAIEAAETLGVDGLNVTIPFKQDVLDAVDPAPLAERIGAVNTVDFTGGTPTGYNTDAVGAVRALDHHDVSLSGTAVVVGAGGAGRAVAFGLADEGLSVRIANRTESKADALADEVPDASGHGLDSLSDLLANADILVNCTSVGMEEDKTPVPADALHSDLAVLDAVYTPIETRLLQDAAAAGATTVDGAWMLLYQGVEAFERWTGEDAPVDRMNGRLREHL
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: YIDE_SALPA
Sequence: MSDIALTVSVLALVAVVGLWIGNIKVRGVGFGIGGVLFGGIIVGHFVDQAGVTLSGDMLHFIQEFGLILFVYTIGIQVGPGFFASLRVSGLRLNLFAVLIVIMGGLVTAILHKIFAIPLPVVLGIFSGAVTNTPALGAGQQILRDLGTPVDLVDQMGMSYAMAYPFGICGILLTMWLMRLIFRVNVEAEAQKHESSLANGHSLIQTMNIRVENPNLNNMAIQDVPILNSDKIICSRLKRDDTLMVPSPGTIIQAGDLLHLVGQSTDLHNAQLVIGKEVDTSLSTRGTDLRVERVVVTNEKVLGKRIRDLHFKERYDVVISRLNRAGVELVASSDASLQFGDILNLVGRPASIDAVANVVGNAQQKLQQVQMLPVFIGIGLGVLLGSIPLFVPGFPVALKLGLAGGPLIMALILGRIGSIGKLYWFMPPSANLALRELGIVLFLAVVGLKSGGDFVDTLTQGEGLSWIGYGIFITAIPLITVGLLARIFAKMNYLTLCGMLAGSMTDPPALAFANNLHATSGAAALSYATVYPLVMFLRIITPQLLAVIFWGMG
What are the official names of this protein?
Putative transport protein YidE.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family. YidE subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YGFZ_ECOSM
Sequence: MAFTPFPPRQPTASARLPLTLMTLDDWALATITGADSEKYMQGQVTADVSQMTEDQHLLAAHCDAKGKMWSNLRLFRDGDGFAWIERRSVREPQLTELKKYAVFSKVTIAPDDERVLLGVAGFQARAALANLFSELPSKEKQVVKEGATTLLWFEHPAERFLIVTDEATANMLTDKLRGEAELNNSQQWLALNIEAGFPVIDAANSGQFIPQATNLQALGGISFKKGCYTGQEMVARAKFRGANKRALWLLTGSASRLPEAGEDLELKMGENWRRTGTVLAAVKLEDGQVVVQVVMNNDMEPDSIFRVRDDANTLRIEPLPYSLEE
What is the function of this protein?
Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs.  It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication.
What are the official names of this protein?
tRNA-modifying protein YgfZ.
What is the protein family that this protein belongs to?
Belongs to the tRNA-modifying YgfZ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCKA_PSEMY
Sequence: MTQANNAVYTDISAAQLVEEAIRRGEGELAANGALVVRTGHRTGRSPADRFIVQEPSTEAQIAWGAINRPFPADKFDALWDRVASFNNAQEHFVSHVHVGSAEAHYLPVKMTTATAWQNLFGRQLFINPSAYNPAGKAEWEILNVANFECVPERDGTNSDGCVIINFAAKKVLIAGMRYAGEMKKAMFSVQNFLLPEKDVLPMHCAANIGEEGDVTLFFGLSGTGKTTLSADESRYLIGDDEHGWGEGVVFNIEGGCYAKCIDLSEKNEPVIWKAIQFGTVLENVVLDEQRTPDYSDDSLTQNSRAAYPLEYVEKRSEKNLGGEPNAVIFLTCDLTGVLPPVSILNNEQAAYHFLSGYTALVGSTEMGSGGGIKSTFSTCFGAPFFPRPAGVYAELLIKRINAFGSKVYLVNTGWTGGGYGVGKRFNIPTTRGVIAAIQSGALIGAETEHLPIINLDVPKSVPGVETNLLNPRNTWADKNAYDEAAKGLAKLFIDNFAKFDVSEAIKNAGPQL
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FPG_ACISJ
Sequence: MPELPEVEVTRRSFAGAIEGATVRGITVGKPLRWPLGTEPAVLVGRRVCGVRRRGKYLLLDLDEGLLLIHLGMSGSLRFARDLPARGAHDHFELITDQGTLRLHDPRRFGAVVWAAGESDPRARKLLDGWGLEPLGEDFAFETFHAGLRAKRTPIKQLLLAGTVVVGVGNIYACEVLFLAGIRPTTRACAIGPQRARRLHGAIREVLARAVERGGSTLRDFSSADGSAGHFQLEANVYGRAGLPCRQCGTPVRLLRQGQRSTYFCPHCQRA
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: METXA_MYCMM
Sequence: MTISDVPTQTLPAEGEVRLVDIGSLRLESGAVIDNVCIALQRWGELSPTRDNVVMVLHALTGDSHVTGPAGPGHSTPGWWDGMVGPGAPIDTNRWCAVATNVLGGCRGSTGPSSLARDGKPWGSRFPLISVRDQVEADMAALAALGITQVAAVVGGSMGGARALEWIVGHPDRVRSALLLAVGARATADQIGTQTTQIAAIKADPNWRNGDYHETGCKPEAGLKVARRFAHLTYRGEIELDSRFANDGQGGEDPADGGRYAIQSYLEHQGDKLLARFDAGSYVILTEALNRHDVGRGRDGIHAALRGCPVPVVVGGITSDRLYPLRLQQELADLLPGCAGLEVVDSIRGHDGFLVESEAVGELIHKTLRLAEDRSSRPW
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3641_PROMH
Sequence: MAKQPEEWHYLNPEFDNTPLEEEEEEEIIWVSKSEIKRDAEALKKLGTELVELSAQELERVPLDEKLLASIKLAQKVQREARRRQIQYIGKLLRNVDEEPIRQALDKLKNRHNQQILVLHKLEDLRTRLIDGGNEVIEEVVALYPMADRQQLRTLIRNAKKEKEANKPPKSFRLLFQYLKDLSESA
What are the official names of this protein?
UPF0307 protein PMI3641.
What is the protein family that this protein belongs to?
Belongs to the UPF0307 family.
Protein: SANBR_MOUSE
Sequence: MSRGYPENNNFLNNNNQMVLDMILYPLIGIPQTINWETVARLVPGLTPKECVKRFDELKSCGSSPVDNQYNPLMATGEGPVETLATYIKSSLLDTQGDFQETPVDQDTVSKAGRHSIATTRNCSSESENCTARNAGEETGESEGPNMVIHVCDEAKSLKEDFICPRDLLISEMKYFAEYLSMDAQRWEEVDISVHCDVHIFNWLIKYVKRNTKESKDCEIPALEPGNVISILISSEFLKMDSLVEQCIQYCHKNMNAIVAAPCNMNCINANLLTRIADLFTHNEIDDLKDKKDKFRSKLFCKKIERLFDPEYSNPDSRNNAATLYRCCLCKKLLTRETERRIPCIPGKINVDRHGNIIYIHIRDKTWDVHEYLNSLFEELKSWRDVYWRLWGTVNWLTCSRCYQAFLCIEFSHCQYHSEVVVYSSTVNSLNTVGTGIYPCCNQKVLRFDPTQLTKGCKVRDHMVVLHDQGENDDSPSCPPAKILDDLHKHKDVIAVPFLKDAVSDPGVGSCDEKGLEYEILLEPNTPWGSKTGELNAFLSLKNWTLQLKQQSLFSEEEEYTTGSEVTEDEVGDEEEIAKKQRKKEKPKKFTKPPKKQLSSPCSQKKEKTLEKSTSRDVSPFVVSMQKNKWDASRSLRFNQDAQREDDQRRMSEITGHLIKMRLGDLDRVKAKESKEFAGGIYSRLEAQVRASVPVTARQNSSDKNQRSKSRFGQGRPA
What is the function of this protein?
Negatively regulates class switch recombination or isotype switching in splenic B-cells.
What are the official names of this protein?
SANT and BTB domain regulator of class switch recombination, SANT and BTB domain regulator of CSR.
What is the protein family that this protein belongs to?
Belongs to the KIAA1841 family.
Protein: TXA_ANDCR
Sequence: ADVPGNYPLDSYGNCYPCTILGDNQYCI
What is the function of this protein?
Binds to sodium channels (Nav) and affects the channel activation process.
What are the official names of this protein?
Toxin a, Subcomponent a.
What is the protein family that this protein belongs to?
Belongs to the long (3 C-C) scorpion toxin superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RPOC_BURCJ
Sequence: MKALLDLFKQVQQEEVFDAIKIGLASPDKIRSWSFGEVKKPETINYRTFKPERDGLFCAKIFGPIKDYECLCGKYKRLKHRGVICEKCGVEVTLAKVRRERMGHIELASPVAHIWFLKSLPSRLGMVLDMTLRDIERVLYFEAYVVIEPGMTPLKARQIMTEEDYYNKVEEYGDEFRAEMGAEGVRELLRAINIDEQVETLRTELKNTGSEAKIKKYAKRLKVLEAFQRSGIKPEWMILEVLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPEIIVRNEKRMLQEAVDSLLDNGRRGKAMTGANKRPLKSLADMIKGKGGRFRQNLLGKRVDYSGRSVIVVGPTLKLHQCGLPKLMALELFKPFIFNKLEVMGVATTIKAAKKEVENQTPVVWDILEEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQMEARTLMLASNNVLFPANGDPSIVPSQDIVLGLYYATREAINGKGEGLSFTGVSEVIRAYENKEVELASRVNVRITEMVRNEDTSEGAPEFVPKITLYATTVGRAILSEILPHGLPFSVLNKPLKKKEISRLINTAFRKCGLRATVVFADQLMQSGFRLATRAGISICVDDMLVPPQKETIVGDAAKKVKEYDRQYMSGLVTAQERYNNVVDIWSATSEAVGKAMMEQLSTEPVIDRDGNETRQESFNSIYMMADSGARGSAVQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVTQDLVVVEDDCGTSNGVAMKALVEGGEVVEALRDRILGRVAVADVVNPETQETLYESGTLLDETAVEEIERLGIDEVRVRTPLTCETRYGLCAACYGRDLGRGSLVNVGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAVASSVEAKSNGIVRFTATMRYVTNAKGEQIVISRSGEAMITDDFGRERERHKVPYGATLLQLDGATIKAGTQLATWDPLTRPIITEYGGTVKFENVEEGVTVAKQIDDVTGLSTLVVIDVKRRGSQASKSVRPQVKLLDANGEEVKIPGTEHAVQIGFQVGALITVKDGQQVQVGEVLARIPTEAQKTRDITGGLPRVAELFEARSPKDAGILAEVTGTTSFGKDTKGKQRLVITDLEGNQHEFLIAKEKQVLVHDAQVVNKGEMIVDGPADPHDILRLQGIEALSRYIVDEVQDVYRLQGVKINDKHIEVIVRQMLRRVQITDNGDTRFIPGEQVERSDMLDENDRMIAEGKRPASYDNVLLGITKASLSTDSFISAASFQETTRVLTEAAIMGKRDDLRGLKENVIVGRLIPAGTGLAFHKARKAKESSDRERFDQIAAEEAFDFGTPSAPAEEPQHPAAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: RL18_BACHK
Sequence: MITKADKNATRKKRHARVRAKLTGTAERPRLNVFRSNQHIYAQVIDDVNGVTLVSASTLDKDLALNGTSNIEAATKVGESVAKRAVEKGVKEVVFDRGGYLYHGRVKALAEAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RL36_MYCTU
Sequence: MKVNPSVKPICDKCRLIRRHGRVMVICSDPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36, Ribosomal protein B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: GCH4_PSEE4
Sequence: MTSLTLPDIAAQSAQQPLPLDWVGMCGIAMPVQFEGRQLSALADAGVSLDDGASRGIHMSRLYLALEALERDTLTPRLIHQVLEQFLFSHEGLSASAHLRLQFDHLLKRPALVSPLAGWKHYPVAIDARLKAEMFHVELSVEIPYSSTCPCSAALARQLIQERFDQDFTGQAVDRQGVRAWLGSSSGIVATPHSQRSMAKLQVRLVGDELPVTVLIDKAEAALGTAVQTAVKRADEQAFALANGQNLMFCEDAARRLNLALRQLDWVAGFTVRVEHAESLHAHDAVAVSRFQR
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.