PharMolix/UniProtQA huggingface dataset:
Protein: GRIA3_MACFA
Sequence: MARQKKMGQNVLRAVFFLVLGLLGHSHGGFPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFSVTNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFPTDADVQFVIQMRPALKGAILSLLGHYKWEKFVYLYDTERGFSILQAIMEAAVQNNWQVTARSVGNIKDVQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANLGFTDILLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNAPLKYTSALTHDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNIQFDTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERFVPFSDQQISNDSASSENRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFASIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGTGGCGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCYKSRAESKRMKLTKNTQNFKPAPATNTQNYATYREGYNVYGTESVKI
What is the function of this protein?
Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission.  L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.  Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse.  The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist.  In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate (By similarity).
What are the official names of this protein?
Glutamate receptor 3, GluR-3, AMPA-selective glutamate receptor 3, GluR-C, GluR-K3, Glutamate receptor ionotropic, AMPA 3, GluA3.
What is the protein family that this protein belongs to?
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIA3 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi- pass membrane protein. Note=Interaction with CNIH2 and CNIH3 promotes cell surface expression.
Protein: SIAT2_MOUSE
Sequence: MKPHLKQWRQRMLFGIFVWGLLFLAIFIYFTNSNPAAPMPSSFSFLERRGLLPLQGKQRVIMGALQEPSLPRSLDASKVLLDSHPENPFHPWPGDPQKWDQAPNGFDNGDEFFTSQVGRKSQSAFYPEEDSYFFVADQPELYHHRQGALELPSPGETSWRSGPVQPKQKLLHPRRGSLPEEAYDSDMLSASMSRAFLYRLWKGAVSSKMLNPRLQKAMRYYMSFNKHGVRFRRRGRREATRTGPELLCEMRRRVRVRTLDGREAPFSGLGWRPLVPGVPLSQLHPRGLSSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTVRIINSQILANPSHHFIDSALYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRRKYPTQPFYILHPKFIWQLWDIIQENTREKIQPNPPSSGFIGILIMMSMCKEVHVYEYIPSVRQTELCHYHELYYDAACTLGAYHPLLYEKLLVQRLNTGTQADLHHKGKVVLPGFQTLRCPVTSPNNTHS
What is the function of this protein?
Transfers sialic acid from the donor of substrate CMP-sialic acid to galactose containing acceptor substrates.  Has alpha-2,6-sialyltransferase activity toward oligosaccharides that have the Gal-beta-1,4-GlcNAc sequence at the non-reducing end of their carbohydrate groups, but it has weak or no activities toward glycoproteins and glycolipids.
What are the official names of this protein?
Beta-galactoside alpha-2,6-sialyltransferase 2, Alpha 2,6-ST 2, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 2, ST6Gal II, ST6GalII, Sialyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 29 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Protein: MDTK_SALPC
Sequence: MQKYTSEARQLLALAIPVILAQVAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLVMIVLWNAGYIIRSMHNIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFLGLLVNIPVNYIFIYGHFGMPELGGIGCGVATAAVYWVMFIAMLSYIKHARSMRDIRNEKGFGKPDSVVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLGVGICMAVVTAIFTVTLRKHIALLYNDNPEVVALAAQLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFFITFTAYWVLGLPSGYILALTDLVVDRMGPAGFWMGFIIGLTSAAVLMMLRMRYLQRQPSAIILQRAAR
What is the function of this protein?
Multidrug efflux pump that functions probably as a Na(+)/drug antiporter.
What are the official names of this protein?
Multidrug resistance protein MdtK, Multidrug-efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CHEB2_HAHCH
Sequence: MNAKIKVLLVDDSAVVRQVLQQVLERDKNIEVIGAAADPIFAQLRMSKQWPDVIVLDVEMPRMDGITFLKKLMAERPTPVVMCSTLTSKGAQTSMKALAAGAVAVVAKPAVGVKEYLESAAGELIMEIKAAAKANMRNMPAATASAQSMALPAKFSADAVIPLRTGGVIAGANKIAALGTSTGGTQALEYVLTRLPRNCPGIVIVQHMPEKFTAAFAERLNSICELEILEAESGHQVAPGRALIAPGGKHMLLRRSGAQYFVEIMSGPPVNRHRPSVDVLFRSVAQAAGRNALGVIMTGMGDDGAKGLLEMRNAGALTIGQDERSCIVYGMPKEAAKIGAVTREISLERIPQCVLDMGASLTASAQRG
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 2.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ESXO_MYCTU
Sequence: MTINYQFGDVDAHGAMIRAQAGLLEAEHQAIVRDVLAAGDFWGGAGSVACQEFITQLGRNFQVIYEQANAHGQKVQAAGNNMAQTDSAVGSSWA
What is the function of this protein?
Plays an important role in mycobacterial pathogenesis in the context of innate immunity.  Aids host cell invasion and intracellular bacillary persistence.  Increases host oxidative stress response, leading to genomic instability and decrease in macrophage viability.  Also induces autophagy and modulates the immune function of macrophages.
What are the official names of this protein?
ESAT-6-like protein EsxO.
What is the protein family that this protein belongs to?
Belongs to the WXG100 family. ESAT-6 subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Probably secreted via the ESX-5 / type VII secretion system (T7SS).
Protein: ISPG_ECOLI
Sequence: MHNQAPIQRRKSTRIYVGNVPIGDGAPIAVQSMTNTRTTDVEATVNQIKALERVGADIVRVSVPTMDAAEAFKLIKQQVNVPLVADIHFDYRIALKVAEYGVDCLRINPGNIGNEERIRMVVDCARDKNIPIRIGVNAGSLEKDLQEKYGEPTPQALLESAMRHVDHLDRLNFDQFKVSVKASDVFLAVESYRLLAKQIDQPLHLGITEAGGARSGAVKSAIGLGLLLSEGIGDTLRVSLAADPVEEIKVGFDILKSLRIRSRGINFIACPTCSRQEFDVIGTVNALEQRLEDIITPMDVSIIGCVVNGPGEALVSTLGVTGGNKKSGLYEDGVRKDRLDNNDMIDQLEARIRAKASQLDEARRIDVQQVEK
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate, using flavodoxin as the reducing agent.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase, Protein GcpE, Protein E.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: FOLC_BUCAP
Sequence: MHKKKYTFSMWMKYLEKFDKKDRKNLFELKLIAKKLGLLNLKSFFFTVGGTNGKGTTCAMLEKLLLDSGYQVGLYTSPHLINYSERIKVNGLYLSEKDHIFSFLIIDAEKGNVSLTYFEFITLSALFLFSQYSLDIIILEVGLGGRLDATNIIDSDLSVITNIGIDHTSCLGTDRISIGREKSGIFRKGKIAVIGEKNIPISVDEIAKEKKTILKKIDVDWFWTRTKIDSWNFIHSNIELYNLPVSRIPLSNTAIALASLFYSGLEVNLKKLKSSISKVQLSGRFQTVFNSPRIILDVAHNVHAALYLSEKIDEIDTEGQIYAVFGILKDKDVAGVVQVLQKKINYWYVVNLKTNRSASINYLKKKLSLNNALFFNNINESWQAIKKVITKKDIILVFGSFFTVSEFMSIKDRRLTLY
What is the function of this protein?
Functions in two distinct reactions of the de novo folate biosynthetic pathway.  Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu).  Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.
What are the official names of this protein?
Dihydrofolate synthase/folylpolyglutamate synthase, DHFS / FPGS, Folylpoly-gamma-glutamate synthetase-dihydrofolate synthetase, Folylpolyglutamate synthetase, Tetrahydrofolylpolyglutamate synthase.
What is the protein family that this protein belongs to?
Belongs to the folylpolyglutamate synthase family.
Protein: MCE_FOWPN
Sequence: MHEGHQESFKELEMTKPYMFFNELVGEEDYNKELENSNTKFQGQGQLKLLLGELYFLNTLIKNKTLCSDTVIVYIGSAPGSHINFLYHYMDDLKIDLKWILIDGRDHDRSLESLKNVSIIHRFVDEQYLFKLRNMIRKNHKIVLISDIRSLRGKEPTSEDLLHDYALQNQMVSILKPIASSLKWRCPFPDQWIRDFYIPCGDEFLQPFAPPFSAEMRLLSCYSRAPIRLIRIDKNAAIEYEKKMFYLNTKIRPKIVLDFDYPNQKYDYFYMFYILKDIVLPTYKEFSTYKQKVIFLQEAIFNALNIKP
What is the function of this protein?
Displays methyltransferase, positive regulation of the poly(A) polymerase and transcription elongation activities.  Involved in the modification of both mRNA ends and in intermediate and late gene positive transcription elongation.  At the mRNAs 5' end, methylates the ribose 2' OH group of the first transcribed nucleotide, thereby producing a 2'-O-methylpurine cap.  At the 3' end, functions as a processivity factor which stimulates the activity of the viral poly(A) polymerase OPG063 that creates mRNA's poly(A) tail.  In the presence of OPG102, OPG063 does not dissociate from the RNA allowing tail elongation to around 250 adenylates.
What are the official names of this protein?
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase, Poly(A) polymerase regulatory subunit, Poly(A) polymerase small subunit, PAP-S, VP39.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Poxvirus/kinetoplastid 2'-O-MTase family.
What are the subcellular locations of this protein?
Virion. Note=Localizes to the virion core.
Protein: NEUL4_XENTR
Sequence: MAELHPRTGKLISLSNGNRTAARKQPAQEFNQGLVVSARPLGPGEVFTVRLDRKMNSWSGSMEIGLTTQDPAFLDFPSSATGLKGGSWIVSGCSVLEDGRSVLEEYGQDLDQLGEGDRVGVQRSISGELHLWVNGRDCGAASCGIPPRVWAVVDLYGKCTQITVLSCQPPPEEEEEEDAEEQEGSLVPLGQSRPDKFPNSLDTDSGFPSTELSAVVSNAILSAYHGSLLSVSLGSPPAAIEHSPPTCNDALLFHEKCGTLIKLSNGNKTAERRRPLDEFNNGVVMTNRPLRDCEMFEIRIDKLVDKWSGSIEIGVTTHNPNSLEYPATMTNLRSGTIMMSGCGILTNGKGTRREYCEFSLDELQEGDHIGLTRKSSGALHFYINGMDQGVASCQTPPVVYGVVDLYGMAVKVTIVHNHNHADRLRRNNAILRARSPDTGRHSSSTPEPGQLLFHSNCGQKASIINGGRTALRPHATDDFNHGVVLSNRPLQNNEVFQVRIDKMVDKWAGSIEIGVTTHNPAYLQLPSTMTNLRSGTWMMTGNGVMHNGTTILDEYGHNLDRLKAGDTVGVVRREDGTLNFFVNGIAQGVAAWNVPPNVFAVVDLYGQAAQATIMDESDALPLPGDEDEGLALTPGTPCALLSLSDLRFHHLHGANALITNGGRTVLRKNSRSEFNDAIVMSSRPLRDGEMFEIVIQKMVDRWSGSIEAGVTAIRPEDLEFPNTMTDIDYDTWMLSGTAIMQDGNTLRNNYGCDLDSLGAGSRIGMMKTIRGDLHYFINGEDQGVACTGLPMGRDIYAVIDLYGQCVQVSLTGGSGLVDNSLSASHVTDKSLPSQSPVPSVSHRFHTVCGKNVSVLCDGTRAERGAGCSHGIVFSSRELLTNETFEIRVEKIEPHWSGSCNIGVTSLSPHEVSLLGGGLPERALELRSKVTWLVCGSEVTRNGQRLRENYCNSLERVRVGSRLGVRRDSDDTLHILMNGEDMGPAACGIPKAVYAVLDIHGCITALSTVSSSLLEEPDATKPPSITSESEEEEDPADHGDPHTVIQAHSLQFLANHGKNILLSHGNRTATRVSSYNQGIVVLPQPLPRLFLFQIRIDQLSPHWTSSLSIGVIAVSPERLNFPATAAALKRSSWIFQRSAVLCNGVKIREGYGPNLDLCPEGTCLGLLLDSSGGLHLYVNGLDQGVGAQDLPEVCYVLVDLYGQCEQVSIVTGEAQGAELDAHEGQLPGEREKADMVDGVKESLCWVPPDPVALLSCEYLALCTRFKDLLLLPDGYFLEDSKLCVCHCDSCHKLRGDETYRKRGDPPREYAEPIGWCSFPLRLSPRSSCAQYKKWHIAYQGSSAGTIRRTLDRGDLLPGSACILTSVPAKSDPQSGFPAAEPNVLPPRDLQSVVLSPTLRYAALPEMCPKVMFRDPRSQRMFGAQVALQVCVRPGSYKTGPPSACAIDLMDPRIPSSEMEFLTKEKGATVLRGLLVRVE
What is the function of this protein?
Promotes CCP110 ubiquitination and proteasome-dependent degradation.  By counteracting accumulation of CP110, maintains normal centriolar homeostasis and preventing formation of ectopic microtubular organizing centers (By similarity).
What are the official names of this protein?
Neuralized-like protein 4.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole.
Protein: FEN1_SOYBN
Sequence: MGIKGLTKLLADNAPKSMKENKFESYFGRKIAIDASMSIYQFLIVVGRSGTEMLTNEAGEVTSHLQGMFSRTIRLLEAGIKPVYVFDGKPPDLKKQELAKRYSKRAEATEDLSEALETANKEDIEKFSKRTVKVTKQHNDDCKRLLRLMGVPVVEAPSEAEAQCAALCKAGKVYGVVSEDMDSLTFGAPKFLRHLMDPSSKKIPVMEFEVAKILEELNMTMDQFIDLCILSGCDYCDSIRGIGGLTALKLIRQHGSIENIPENLNKERYQIPDNWPYQEARRLFKEPLVITDEKELDIKWSSPDEEGLITFLVNENGFNRDRVTKAIEKIKVAKNKSSQGRLESFFKPTANPSVPIKRKETPVNNAKETNKKTKAGGGKKKK
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: BARAC_PYRHO
Sequence: MVSMTKWDEIRKYTSKKIEKNLEIVKLDEKYIPRASGFKYYPMVIERSSGSRIWDKDGNEYIDFLTSAAVFNVGHTHPGVVKAVEEQIKKFFNYTMGYLYVEPPVRLAELLVEITPGNFEKKVTYGFSGSDAVDSSIKAARAYTKRVNIISFLHSYHGMTYGALSATGILDPKLKKLLHPMGNFHHVEFPDPYRNSWGIDGYEDPSELANRALDEIERKIKELNEDVAGIIIEPIQGDAGVVIPPEEFVRDLKKLTEEYGIVFIDEEVQTGMGRTGRWWGIEHFGVTPDLIVSAKALGGGMPISAVVGKAEIMDSVPVPFFVFTHIGHAVNASAAIATINVIKEEKLVERSEKLGEYMLKRLRELQETYPIIGDVRGKGLLIGVDIVKEGTREPDRSLAQKISWRAWEKGLIMITFGKHGNVLRIAPPLNIPQEDLDKGVEIIEESIKDAVEGKIPDEVLKFLRAW
What is the function of this protein?
Amino-acid racemase able to utilize a broad range of substrates (PubMed:25963389).  Can use Met, Leu, Phe, Ala, Ser, Ile, Val, Trp, Tyr and Thr (PubMed:25963389, PubMed:28343923).  Is mostly active with Phe, Leu, Met and Tyr, followed by Ile, Thr and Trp.  Has weaker activity with Val, Ser and Ala (PubMed:28343923).  Shows no activity toward Pro, Asp, Glu, Arg, His, Gln and Asn (PubMed:25963389, PubMed:28343923).
What are the official names of this protein?
Broad substrate specificity amino-acid racemase, BAR.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
Protein: RL16_STRPB
Sequence: MLVPKRVKHRREFRGKMRGEAKGGKEVSFGEYGLQATTSHWITNRQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKVMFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: RL9_BOVIN
Sequence: MKTILSNQTVDIPENVDINLKGRTVIVKGPRGTLRRDFNHINVELSLLGKKKKRLRVDKWWGNRKELATVRTICSHVQNMIKGVTLGFRYKMRSVYAHFPINVVIQENGSLVEIRNFLGEKYIRRVRMRPGVACSVSQAQKDELILEGNDIELVSNSAALIQQATTVKNKDIRKFLDGIYVSEKGTVQQADE
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAIA_PARMW
Sequence: MARPGLTIALLLTTPNLVDACQQWLPDTRYHSIVLSGPHQGQEQLDLVSTLEAQQEEIDAVVVEQQLLDASSRDQLLGRGLLFPAVVVGEMKGHVDYHAEELHLAEDQLAQLGYTVDAAISRFLRQGRADGRSDDDGLASVDKLSRRLQERLGYLGVFYKRDPSRFLGSLPTEERRELLESLQRTYRDLLISYFSDPAASNQALESFVNTAFFSDLPITRTVDIHVDQIDEFWKQLRLEGNKSEFLQDYRLALLDVMAHLCEMYRRSIPPDIPLSGLASGRHRREADLPDAPEVSS
What is the function of this protein?
Binds oxidized quinones via the N-terminal PsR domain, allowing it to sense redox changes and possibly mediate clock input.
What are the official names of this protein?
Circadian clock oscillator protein KaiA.
Protein: CBPM_ECOL6
Sequence: MANVTVTFTITEFCLHTGISEEELNEIVGLGVVEPSEIQETTWVFDDHAAIVVQRAVRLRHELALDWPGIAVALTLMDDIAHLKQENRLLRQRLSRFVAHP
What is the function of this protein?
Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA.  Together with CbpA, modulates the activity of the DnaK chaperone system.  Does not inhibit the co-chaperone activity of DnaJ.
What are the official names of this protein?
Chaperone modulatory protein CbpM.
What is the protein family that this protein belongs to?
Belongs to the CbpM family.
Protein: TX1AB_MYRPI
Sequence: MKLSCLLLTLTIIFVLTIVHAPNVEAKDLADPESEAVGFADAFGEADAVGEADPNAGLGSVFGRLARILGRVIPKVAKKLGPKVAKVLPKVMKEAIPMAVEMAKSQEEQQPQ
What is the function of this protein?
Has strong cytotoxic and hemolytic activities.  Is more potent against mononuclear leukocytes than against granulocytes.  The synthesized peptide 57-76 shows a potent and broad spectrum antimicrobial activity against both Gram-positive and Gram-negative bacteria, and also against the fungus C. albicans.  Adopts an alpha-helical structure.
What are the official names of this protein?
M-myrmeciitoxin-Mp1, M-MIITX-Mp1, Allergen Myr p I, Major allergen Myr p 1, Pilosulin-1.
What is the protein family that this protein belongs to?
Belongs to the formicidae venom precursor-01 superfamily. Ant pilosulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPB_STAAR
Sequence: MGIGRVTQVMGPVIDVRFEHNEVPKINNALVIDVPKEEGTIQLTLEVALQLGDDVVRTIAMDSTDGVQRGMDVKDTGKEISVPVGDETLGRVFNVLGETIDLKEEISDSVRRDPIHRQAPAFDELSTEVQILETGIKVVDLLAPYIKGGKIGLFGGAGVGKTVLIQELINNIAQEHGGISVFAGVGERTREGNDLYFEMSDSGVIKKTAMVFGQMNEPPGARMRVALSGLTMAEYFRDEQGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTTKGSVTSIQAVFVPADDYTDPAPATAFAHLDATTNLERKLTEMGIYPAVDPLASTSRALEPSIVGQEHYEVARDVQSTLQKYRELQDIIAILGMDELSDEDKQTVERARRIQFFLSQNFHVAEQFTGQKGSYVPVKTTVANFKDILDGKYDHIPEDAFRLVGSMDDVIAKAKDMGVEV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RS13_STRZP
Sequence: MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVRVRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNTKNNARTRKGKAVAIAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: CATB3_GIAIN
Sequence: MKLFLLAAAAFSAPALTVSELNHIKSLNPRWKAGIPKRFEGLTKDEISSLLMPVSFLKRDRAAVPRGTVSATQAPDSFDFREEYPHCIPEVVDQGGCGSCWAFSSVASVGDRRCFAGLDKKAVKYSPQYVVSCDRGDMACDGGWLPSVWRFLTKTGTTTDECVPYQSGSTGARGTCPTKCADGSDLPHLYKATKAVDYGLDAPAIMKALATGGPLQTAFTVYSDFMYYESGVYQHTYGRVEGGHAVDMVGYGTDDDGVDYWIIKNSWGPDWGEDGYFRIIRMTNECGIEEQVIGGFFEN
What is the function of this protein?
Thiol protease which is required for parasite excystation and invasion of the proximal small intestine of the human host.
What are the official names of this protein?
Cathepsin B-like CP3, Cathepsin B-like protease B3.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Vacuole.
Protein: NADD_LEPIN
Sequence: MNSSILTGIFGGSFDPPHEGHSEILKSFFWEVSDCKEVFVIPNRQNPLKEEKISLPENILEMLNLFVSEFSQSIRILDLELKRSGPSYTIQTIQELKTIYPNRKFVLLIGEDNYSNFHKWKDWEKILTEVETIFVFRRFSKEVPLNSHLNSLFEFKFLENPLIPVTSTDLRKSFFQSKVPNLISKKVLDYILKNKLYSK
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: GLMS_THEVB
Sequence: MCGIVGYIGPQGAAQILLQGLQKLEYRGYDSAGIATLNEGELLCVRAKGKLQNLVEKVEQLDIVAHVGIGHTRWATHGKPEEYNAHPHRDSRDRLAVVQNGIIENYRELRDQLQARGHIFRSETDTEVIPHLIAELLPETPTANGLLEAVRQAVHQLEGAFAIAVICADYPDELIVARQQAPLVIGFGQGEFFCASDTPAIIPYTRAVLPLENGELARLTPTGVEVYDFEGHRLRKTPRTLNWNPVMVEKQGFKHYMLKEIYEQPGVVRACLENYLRADWEVASPFSPVQLNLPPSLLDNLQHIQIVACGTSWHAGLVGKYLLEQVAQIPTSVQYASEFRYAPPPLLPHTLTIGVTQSGETADTLAALEMELKRRQGLDGALQPRLLGITNRPESSLGHLVPHIIDTRAGIEIGVAATKTFVAQLMAFYLLTLELSWQRQSCDRSRLAELVTGLRQLPAQMEQILESQERYIEALSHDFWETQDFIFLGRGINFPIALEGALKLKEISYIHAEGYPAGEMKHGPIALLDAKVPVVTIAMPGSVFEKVLSNAQEARARDARLIGVTPLDEAEAQHTFDNLLPVPEVDELLSPILTVIPLQLLAYHIAARRGLDVDQPRNLAKSVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA_STAES
Sequence: MRKITVFGMGSFGTALANVLAQNGHDVLMWGKNVENVDELNTHHMNKNYLKDAKLDSSIKATVDLNKAVQFSDIYLMALPTKAIREVSKDIDQLLTSKKTFIHVAKGIENDTFKRVSEMIEDSISSEHNGGIGVLSGPSHAEEVVIKQPTTVAASSKDNNVSKLIQDLFMNDYLRVYTNNDLVGVELGGALKNIIAIASGIVAGMGWGDNAKAALMTRGLAEISRLGEKLGADPMTFLGLGGIGDLIVTCTSTHSRNYTLGFKLGQGKTAEEALKEMKMVVEGIYTTKSVYHLAQQEGVEMPITNALYEVLFEDVPVSKSVRTLMERDKKAE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.