PharMolix/UniProtQA huggingface dataset:
Protein: RS17_CHLFF
Sequence: MASEVRGLRKTKVGVVVSSKMDKTVIVRVERVYSHPQYAKVVRDSKKYYAHNDLNVSEGEKVRIQETRPLSKLKRWRVVERIS
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: LGT_BORBZ
Sequence: MPNYINYPSWLHPEVIQGIPITWYSLSYILIILISYKFIWYQIQSDNVDIKKEDYEIFMFSLVLGAILGGRLASTLVYDKSGIYYSNPWLILLPFDQHWNFTGFRGMAIHGGFLGAIIAPLITINTKLKNTNVQKYFLKLTDYGSIAFSSGYILGRLANFANAELYGRVMKGGIIFPNAEPFDTNIPGVKEFASSVGLEISPHDLLINLPRIPSQLIEGFFEGPVTFLLLWFLFKKIKKYDGFIFGVYVMLYAFFRFFIEYLREPDKELGFIITYKPITSLSEFSFLNISMGQILSLTLMLSGLIWIIVTKKIADKKIKNNTNLAYKN
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CUTI1_ASPFU
Sequence: MKFALLSLAAMAVASPVAIDVRQTAITGDELRTGPCEPITFIFARGSTEPGLLGITTGPGVCNALKLSRPGQVACQGVGPAYIADLASNFLPQGTSQVAIDEAAGLFKLAASKCPDTKIVAGGYSQGAAVMHGAIRNLPSNVQNMIKGVVLFGDTRNKQDGGRIPNFPTDRTKIYCAFGDLVCDGTLIITPAHLSYGDDVPSATSFLLSKV
What is the function of this protein?
Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants (By similarity).  Degrades cutin, a macromolecule that forms the structure of the plant cuticle (By similarity).
What are the official names of this protein?
Probable cutinase 1, Cutin hydrolase 1.
What is the protein family that this protein belongs to?
Belongs to the cutinase family.
What are the subcellular locations of this protein?
Secreted.
Protein: HUTI_THEAC
Sequence: MRALTNLSQIATGEGRSFLSGERQADVKVYENHSILIHGGRIAEITRAVPPGVEEIDCGGGVAVPGFVDPHTHIAFAGNRVQEFYMRIRGTSYLDILRSGNGIYRTIRDTVNADENRIFKETISRVWSAVRRGTTTMEMKTGYGLDQRGEEKILSAIEVIKNTGPISVVPTYLAHVVPQDVQENAYVEGILETVKRNRQRISYADIFCDAGAFSPEASRRFLEAAIAMGIPARIHTNEIENVGCVKKTRGLPIVSYDHMIHFDDADLDIVKENGSSVTLLPITVFALNEAYPDARRIIDRGIPVSIATDISPLNMNDDMIFAMHLAVRNNHMNAEEVLNAATINPAASLGLAEKKGTIESGKDADLVVLSARSYDEIPYLYGLDIVSMTISRGNILYSRGDHGITDTSEA
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHBG_PROMH
Sequence: MAHLLIVNADDFGLSRGQNYGIVECHRHGIVTSTTALVNAEGIEHAAQLCKELPHLGVGLHFTLTMGQPLSPIPSLTRNGVLGKWLWQMAEQEQLPLDEIRVELNAQYQRFVELFGCPPDHIDSHHHVHMFKQIFPIVAEFAQQKALPIRVDRLLAQKENLNTQGVISSDGFDSQFYGDEISQALFLKTLDDAKARGEQSLEVMTHPAFIDNPLRVSGYCFQRLTELEVLTQSSLKQAIAERGYQLGTYQDLI
What is the function of this protein?
Involved in the degradation of chitin.  ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose.  Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF.  Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P, the inducer of ChbR and the substrate of ChbF.
What are the official names of this protein?
Chitooligosaccharide deacetylase, COD, Chitin disaccharide deacetylase, Chitobiose deacetylase, Chitobiose-6P deacetylase, Chitotriose deacetylase, Chitotriose-6P deacetylase.
What is the protein family that this protein belongs to?
Belongs to the YdjC deacetylase family. ChbG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EXLYS_BPPH6
Sequence: MSKDSAFAVQYSLRALGQKVRADGVVGSETRAALDALPENQKKAIVELQALLPKAQSVGNNRVRFTTAEVDSAVARISQKIGVPASYYQFLIPIENFVVAGGFETTVSGSFRGLGQFNRQTWDRLRRLGRNLPAFEEGSAQLNASLYAIGFLYLENKRAYEASFKGRVFTHEIAYLYHNQGAPAAEQYLTSGRLVYPKQSEAAVAAVAAARNQHVKESWA
What is the function of this protein?
Muralytic enzyme exposed to host peptidoglycan layer after membrane fusion during viral entry.  Functions as an exolysin that cleaves the peptide bridge formed by meso-diaminopimelic acid and D-alanine.  Also lyses the host cell late in infection to release the virions.
What are the official names of this protein?
Peptidoglycan hydrolase gp5, Gene product 5, Gp5.
What is the protein family that this protein belongs to?
Belongs to the peptidase U40 family.
What are the subcellular locations of this protein?
Virion. Note=Located between the capsid and the envelope.
Protein: RPOB_PSE14
Sequence: MAYSYTEKKRIRKDFSKLPDVMDVPYLLAIQLDSYREFLQAGATKDQFRDVGLHAAFKSVFPIISYSGNAALEYVGYRLGEPAFDVKECVLRGVTYAVPLRVKVRLIIFDKESSNKAIKDIKEQEVYMGEIPLMTENGTFVINGTERVIVSQLHRSPGVFFDHDRGKTHSSGKLLYSARIIPYRGSWLDFEFDPKDCVFVRIDRRRKLPASVLLRALGYTTEQVLDAFYTTNVFHVRGENLSLELVPQRLRGEIAVLDILDDKGKVIVEQGRRITARHINQLEKAGIKELEVPLDYVLGRTTAKVIVHPATGEIIAECNTELNTEILAKIAKAQVVRIETLYTNDIDCGPFVSDTLKIDSTSNQLEALVEIYRMMRPGEPPTKDAAETLFNNLFFSPERYDLSAVGRMKFNRRIGRTEIEGSGVLCKEDIVAVLKTLVDIRNGKGIVDDIDHLGNRRVRCVGEMAENQFRVGLVRVERAVKERLSMAESEGLMPQDLINAKPVAAAVKEFFGSSQLSQFMDQNNPLSEITLKRRVSALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLAAYARTNQYGFLESPYRVVKEGLVTEEIVFLSAIEEADHVIAQASAAMNDKQELIDELVAVRHLNEFTVKAPADVTLMDVSPKQVVSVAASLIPFLEHDDANRALMGSNMQRQAVPTLRADKPLVGTGMERNVARDSGVCVVARRGGVIDSVDASRIVVRVADDEVETGEAGVDIYNLTKYTRSNQNTCINQRPLVSKGDRVQRSDIMADGPSTDMGELALGQNMRIAFMAWNGFNFEDSICLSERVVQEDRFTTIHIQELTCVARDTKLGPEEITADIPNVGEAALNKLDEAGIVYVGAEVGAGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVPTGTKGTVIDVQVFTRDGVERDARALSIEKSQLDEIRKDLNEEFRIVEGATFERLRSALVGRVAEGGAGLKKGQEITNEVLDGLEHGQWFKLRMAEDALNEQLEKAQAYIVDRRRLLDDKFEDKKRKLQQGDDLAPGVLKIVKVYLAIRRRIQPGDKMAGRHGNKGVVSVIMPVEDMPHDANGTPVDIVLNPLGVPSRMNVGQILETHLGLAAKGLGEKINRMLEEQRKVAELRKFLNEIYNEIGGRQESLEDLTDNEILDLAKNLRNGVPMATPVFDGAKESEIKAMLKLADMPESGQMQLFDGRTGNKFERAVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGDHRMEPGMPESFNVLIKEIRSLGIDIDLETE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: HSLU_DESRM
Sequence: MEALTPRQTVRELDKYIVGQEKAKKAVAVALRNRYRRSKLKEDLIDEVVPKNILMIGPTGVGKTEIARRLAKLVKAPFVKIEATKFTEVGYVGRDVESMVRDLVETSIRMLKQEKVEEVEERAKRLADERIIELLAPYPNRPTQTKNPFEMLFGGVQDTQQEDKSWEQQNSRIKFERETLREKMSRCELEKDYLEIEVEDQSTPMLEVFSNSGVEEMGVNMQDVLGSIFPRKKRKRKVTVEEARKILTQQEAQKLIDMDELTAQAVKRAEDHGIIFLDEIDKIATREGTTGSADVSRGGVQRDILPIVEGSTVMTKYGPVKTDHILFIAAGAFHIAKPSDLIPELQGRFPIRVELESLSRSDFEQILTEPQNSLIKQYTELLGTEGLKIEFSKNSLVEIADIAYTVNEQNENIGARRLHTILEKLLEDVSFEAPELNGQSLTIDSDYVREKLKDVVTNRDLSRYIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUMP2_ARATH
Sequence: MADFKPRIEISFLETFICSAFAACFAELCTIPLDTAKVRLQLQRKIPTGDGENLPKYRGSIGTLATIAREEGISGLWKGVIAGLHRQCIYGGLRIGLYEPVKTLLVGSDFIGDIPLYQKILAALLTGAIAIIVANPTDLVKVRLQSEGKLPAGVPRRYAGAVDAYFTIVKLEGVSALWTGLGPNIARNAIVNAAELASYDQIKETIMKIPFFRDSVLTHLLAGLAAGFFAVCIGSPIDVVKSRMMGDSTYRNTVDCFIKTMKTEGIMAFYKGFLPNFTRLGTWNAIMFLTLEQVKKVFLREVLYD
What is the function of this protein?
PUMPS are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation.  This leads to a decrease in the efficiency of oxidative phosphorylation and an increase in heat production.  May be involved in protecting plant cells against oxidative stress damage (By similarity).
What are the official names of this protein?
Mitochondrial uncoupling protein 2, AtPUMP2.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: OMP2A_BRUME
Sequence: MNIKSLLLGSAAALVAASGAQAADAIVAPEPEAVEYVRVCDAYGAGYFYIPGTETCLRVHGYVRYDVKGGDDVYSGTDRNGWDKGARFALMFNTNSETELGTLGTYTQLRFNYTSNNSRHDGQYGDFSDDRDVADGGVSTGTDLQFAYITLGGFKVGIDESEFHTFTGYLGDVINDDVVAAGSYRTGKIAYTFTGGNGFSAVIALEQGGEDVDNDYTIDGYMPHVVGGLKYAGGWGSIAGVVAYDSVIEEWATKVRGDVNITDRFSVWLQGAYSSAATPNQNYGQWGGDWAVWGGAKFIAPEKATFNLQAAHDDWGKTAVTANVAYQLVPGFTITPEVSYTKFGGEWKDTVAEDNAWGGIVRFQRSF
What is the function of this protein?
Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane.
What are the official names of this protein?
Porin Omp2a.
What is the protein family that this protein belongs to?
Belongs to the alphaproteobacteria porin family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: CP6A8_DROME
Sequence: MALTYILFQVAVALLAILTYYIHRKLTYFKRRGIPFVAPHLIRGNMEELQKTKNIHEIFQDHYNKFRESKAPFVGFFFFQSPAAFVIDLELAKQILIKDFSNFSNKGIFYNEKDDPISAHLFNLDGAQWRLLRNKLSSTFTSGKMKLMYPTVVSVANEFMTVMHEKVPKNSVLEIRDLVARFTVDVIGTCAFGIQCNSLRDEKAEFLYFGKRSLVDKRHGTLLNGFMRSYPKLARKLGMVRTAPHIQEFYSRIVTETVAVREKEHIKRNDFMDMLIELKNQKEMTLENGDVVRGLTMEEVLAQAFVFFIAGFETSSSTMGFALYELAKNPDIQDKVRAEVEEVIEQHDQNFTYECTKDLKYLNQVLDETLRLYTIVPNLDRMAAKRYVVPGHPNFVIEAGQSVIIPSSAIHHDPSIYPEPFEFRPERFSPEESAGRPSVAWLPFGDGPRNCIGLRFGQMQARIGLALLIRNFKFSTCSKTPNPLVYDPKSFVLGVKDGIYLKVETV
What is the function of this protein?
Involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
What are the official names of this protein?
Cytochrome P450 6a8, CYPVIA8.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: GBRA6_HUMAN
Sequence: MASSLPWLCIILWLENALGKLEVEGNFYSENVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRLTINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNLQTQKAKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRITSLSLPIVSSSEANKVLTRAPILQSTPVTPPPLSPAFGGTSKIDQYSRILFPVAFAGFNLVYWVVYLSKDTMEVSSSVE
What is the function of this protein?
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
What are the official names of this protein?
Gamma-aminobutyric acid receptor subunit alpha-6, GABA(A) receptor subunit alpha-6.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA6 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: RL11_PSYA2
Sequence: MAKKIDGYIKLQVPAGKANPSPPIGPALGQKGVNIMAFCKEFNAATSNQEPGLPIPTEITVYSDKSFTFIMKSPPAAYLLRKAAGIAKGSGTPNTAKVGKVDRAQLEEIVKTKDADLTAADLDAAIRTIAGTARSMGITVEGV
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: HIS5_GEOTN
Sequence: MTMIGVIDYGMGNLYSVSKALERLGCPYIVSGDKEELARVRGLILPGVGSFRDAMHILRETGLADFIRSAVQDGTPLLGICLGMQLLFDESEENGPTEGLGLLRGRVVRFPGVTNDGEPYKVPHMGWNRLRFHRSSPLLDGVEEGHVYFVHSYYVVPGEEEVVLASSEYDVDVPAVVGRDNVFGTQFHPEKSGAVGMSILNRYVGIVTGRENG
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPD_STRP2
Sequence: MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTGLPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLEKETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHKTIDVSIKQQLKVVKENLK
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: LEUC_SHIB3
Sequence: MAKTLYEKLFDAHVVYEAENETPLLYIDRHLVHEVTSPQAFDGLRAHGRPVRQPGKTFATMDHNVSTQTKDINACGEMARIQMQELIKNCKEFGVELYDLNHPYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQGRAKTMKIEVQGKAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLCNMAIEMGAKAGLVAPDETTFNYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTVVTLQAEEISPQVTWGTNPGQVISVNDNIPDPASFADPVERASAEKALAYMGLKPGIPLTEVAIDKVFIGSCTNSRIEDLRAAAEIAKGRKVAPGVQALVVPGSGPVKAQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNNDRLNPGERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVTGHFADIRNIK
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: FIMC_PORGN
Sequence: MKMKYFHHPSGLLPRLLLLLLLTMGAVACTKEDNPDQPTSDEVATVKMSLDDVEMRGGDLYSGEDLIKKVRIFVFREGLNGLWVLDKQKLFASGQSDFQNPFTISAHAGPRQIYVIANEPDALTTKLDKILFKKELEDMQAPDVNEPIVRPFTMTGMATATLNPQGTVQANISLNRIAAKITLDIKQVTPGSDVIKITKVQILRNAKNSRLLEGTNKPTGYWNWANACDLPLTNNGSAQSIIQASAPLYVYENIGSDSDSSGRATQLVVEALYNGIKTRYYAYVNDKTTTANHHYSIRRNHHYKLDGTITKMGEFSSLLLTTTVLPWTVENLDYGFLVPYVAEINPHAVITQDNVVTFENSLSFTVRIKGRDGSRWKATLDNGLEFGFDSGSAIDGAADGTTVYTIKVKALKPNGIGIQRRTNLFFTVDGKKVILDKNINPQPTDIKIIQQGL
What is the function of this protein?
Minor component of fimbriae.  These long, filamentous pili are attached to the cell surface; they mediate biofilm formation, adhesion onto host cells and onto other bacteria that are part of the oral microbiome.  They play an important role in invasion of periodontal tissues and are major virulence factors.  FimC, FimD and FimE contribute to interaction with host CXCR4 and thereby down-regulate the TLR2-mediated host immune response.
What are the official names of this protein?
Major fimbrium subunit FimC.
What is the protein family that this protein belongs to?
Belongs to the bacteroidetes fimbrillin superfamily. FimA/Mfa1 family.
What are the subcellular locations of this protein?
Fimbrium. Cell outer membrane. Note=Probably synthesized as a palmitoylated precursor. Efficient export to the outer membrane and integration into fimbriae requires lipidation and subsequent proteolytic removal of the lipidated propeptide. Probably part of the fimbrium tip, as a part of the complex formed by FimC, FimD and FimE.
Protein: MNTA_APHF2
Sequence: MQDKIPTIAELRELSLRLLTKIPYLKMLVLFGSRATGNINANSDWDFAVLYDEEKYNLYIQNNPLAAFVIPGILGEIFKINSDKIDIVELNHCSKLIAHFVARDGKVLYEEPGDEFDKFQQRVLLSNTEIKKIEKTKLENIENFLQRWGV
What is the function of this protein?
Antitoxin component of a type VII toxin-antitoxin (TA) system.  Upon cloning in E. coli neutralizes the effect of cognate toxin HepT.  Neutralization is mostly due to di-AMPylation of toxin by this enzyme.  Successively di-AMPylates HepT on 'Tyr-109'.  In vitro will use ATP, dATP, GTP, dGTP, TTP or UTP to generate a mono-modified protein, but requires a purine nucleotide for the second modification reaction (ATP, dATP or GTP).
What are the official names of this protein?
Protein adenylyltransferase MntA, Antitoxin MNT, Minimal nucleotidyltransferase, Protein adenylyltransferase MNT.
What is the protein family that this protein belongs to?
Belongs to the MntA antitoxin family.
Protein: MURA_ORITB
Sequence: MSSILVEGGKSLRGEINISGAKNAALPIIVASLLSSKTLVINNVPQLSDVSDMLFILKSCGVHVEIVGSGTIALTANNISGHFSPPCNIVKKMRASIWILAPLLLRLGQVRIASPGGCAIGQRRIDLHLAALKAFGANIQLEDDYISANCSSRMHGISFKFDKVSVGATITAIMCAVLANGSTKLANCAQEPEIADLCYCLRKMGANITGIGTANISIIGVKELNGANYSIIPDRIEAGTYMVAAAITQGKIKLNNVIFKHLKSAITKLRLSGAIIQYQNENSLIIEGANIIKPLNIQTNPYPKFPTDLQAQFMSLMSIADGVSIITENIYENRYMHVFELIKMGANIVIQSREAVVTGVKKLHGADVIATDLRASVSLVLAGLSAVGITKVKRMHHLDRGYESLVEKLQNCNARVQRIPD
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_CLOBK
Sequence: MNRRKSREVAMRLLFQTTLNGENLEEALENLKDVRESEEITKEKDYESVDLKDVDIDYVKRIIKGIEENKEEIDEKIKGNLKNWKIERLSKVDLSILRLCTYELKFEEDIPNRVSVNEAIELAKKYSGEKSATFINGVLGKMI
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: CIRBA_XENLA
Sequence: MSDEGKLFIGGLNFETNEDCLEQAFTKYGRISEVVVVKDRETKRSRGFGFVTFENVDDAKDAMMAMNGKSVDGRQIRVDQAGKSSGERRGGYRGGSSGGRGFFRGGRGRGGGDRGYGSSRFDNRSGGYGGSSGSRDYYGSGRSQGSYGDRSGGSYRDSYDSYATHE
What is the function of this protein?
Cold-inducible mRNA binding protein.  Acts cooperatively with elavl1/elrA to stabilize AU-rich sequence (ARE)-containing mRNAs by binding to them and inhibiting their deadenylation (By similarity).  Essential for embryonic gastrulation and neural development, acting to maintain the expression of a set of adhesion molecules and cell movement during embryogenesis.  Plays a role in the specification and migration of pronephros cells during embryonic kidney development.
What are the official names of this protein?
Cold-inducible RNA-binding protein A, Cold-inducible RNA-binding protein, XCIRP, Cold-inducible RNA-binding protein 1, XCIRP-1, Glycine-rich RNA-binding protein CIRP-A.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Cytoplasm. Note=Shuttles between the nucleus and cytoplasm. Predominantly cytoplasmic in oocytes. Translocates from the nucleus to the cytoplasm upon arginine methylation (By similarity).
Protein: YQAK_BACSU
Sequence: MATNQSIKNNIQKKQKNVPVQQQGATMKGLLSSPSVIKRFEEVLGKRATQFTASILSLYNSEQMLQKTDPMSVISSAMVAATLDLPIDKNLGYAWIVPYGGKAQFQLGYKGYIQLALRTGQYKSINCIPIHEGELQKWNPLTEEIEIDFEKRESDAVIGYAAYFELINGFRKTVYWTKAQVEKHKKKFSKSDFGWKNDWDAMALKTVLKAVLSKWGILSVEMQKAVIEEDETRERIDITNEADSSEIIDSEPSNKDETEKPSAQETDPFDGKPVDIKDDELPFD
What are the official names of this protein?
Uncharacterized protein YqaK.
Protein: DAPF_BEII9
Sequence: MSALANRFVTKMNGLGNAIVVLDLRGTGIVISAAEARAIGQGKGLHFDQLMVLHDPLSPGSAAFMRIYNIDGSLAGACGNGTRCVAWTLLREDHRIGAELMLETAAGQLACLKLAEDRFSVDMGKPAFAWDAIPLAHPVPDTNAVDLARDLAVLPPVDPDALRKASMVNMGNPHAVLFVADQDACDLALVGPVLEHHPLFPDRANISIATVVSPDHIVLKVWERGAGATLACGSAACATLVAAVRHGLAAREARISLPGGDLTIAWRAADDHVIMTGPVTFEFTTRLDPSLFQALVA
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBY_GRATL
Sequence: MDIRLLIVLLPVLAAASWALYNIGRVALQQFRSM
What is the function of this protein?
Manganese-binding polypeptide with L-arginine metabolizing enzyme activity.  Component of the core of photosystem II.
What are the official names of this protein?
Photosystem II protein Y.
What is the protein family that this protein belongs to?
Belongs to the PsbY family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CDK9_XENTR
Sequence: MAKNYDSVEFPYCDEVSKYERLAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEICRTKISPTANQYNRCKGTIFLVFDFCEHDLAGLLSNAHVKFTLSEIKKVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNKYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLTLISQLCGSITPEVWPNVDKYELYQKLELPKGQKRKVKERLKAYVKDLYALDLIDKLLVLDPAQRIDSDDALNHDFFWSDPMPSDLKNMLSTHNQSMFEYLAPPRRRGGHMPQQPANQARNPAATNQSEFDRVF
What is the function of this protein?
Member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II) and SUPT5H.
What are the official names of this protein?
Cyclin-dependent kinase 9, Cell division protein kinase 9.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Nucleus.