PharMolix/UniProtQA huggingface dataset:
Protein: AROA_COXBR
Sequence: MDYQTIPSQGLSGEICVPGDKSISHRAVLLVAIAEGQTQVDGFLMGADNLAMVSALQQMGASIQVIEDENILVVEGVGMTGLQAPPEALDCGNSGTAIRLLSGLLAGQPFNTVLTGDSSLQRRPMKRIIDPLTLMGAKIDSTGNVPPLKIYGNPRLTGIHYQLPMASAQVKSCLLLAGLYARGKTCITEPAPSRDHTERLLKHFHYTLQKDKQSICVSGGGKLKANDISIPGDISSAAFFIVAATITPGSAIRLCRVGVNPTRLGVINLLKMMGADIEVTHYTEKNEEPTADITVRHARLKGIDIPPDQVLLTIDEFPVLLIAAAVAQGKTVLRDAAELRVKETDRIAAMVDGLQKLGIAAESLPDGVIIQGGTLEGGEVNSYDDHRIAMAFAVAGTLAKGPVRIRNCDNVKTSFPNFVELANEVGMNVKGVRGRGGF
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MODC_PSEF5
Sequence: MSIHVKLHLGYQDFALDLDLQLPGRGVTALYGHSGSGKTTCLRCIAGLEKAGRGRIQINDEVWQDSQRKLFVPPHKRSLGYVFQEASLFAHLSVQANLEFGLRRIAKAQRRVDMAQATELLGIGHLLQRHPQHLSGGERQRIGIARALLTSPRLLLMDEPLAALDSKRKSEILPYLERLHDELDIPVLYVSHSQDEVARLADHIVLLSDGRALASGPVGETLARLDLPLALGDDAGVVVEGRVSHYDPDYQLLTLQLPGSQLTIRVAHEPLALGKALRFKVQARDVSLSLQDSEHSSILNRLPVTVRDEIPADNAAHVLVRLDVAGSPLLARITRFSRDQLSLHPGQQLWAQIKAVAVLA
What is the function of this protein?
Part of the ABC transporter complex ModABC involved in molybdenum import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Molybdenum import ATP-binding protein ModC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: IML1_CANGA
Sequence: MFSALRSKNQSNKRSNDDSINSRKDVNELSLGAGGTSTSTNTNHNDSPSIKNKNKNKNKNKTENENIYKLTISSGRSRGTASNTTNANTLVLNAGVAIVGKAPIASSQNEIQTISGQSLQSGIDTNLMTAGFGRSAGIDSTTTVSHDANSVKSRLQRLPTITTSYKEINNGNKPVQVEPQDDSHYTSSLLVDTDPRSNNQPQSISSNAVANVEINRTLQLDLVYHESRVSEKLVMLDLKKLPHIKEGQLCELRTYRKRKSTSARSNKNSRDKKLYFIAHDFDEETRKRCHKFGNISVALGQLQLLLDLPPRSRVWIKPKRKEDTAADLIELHIKDILVNRGDMWCMSSELVDTCVFTGQRIMFLDSIRTTVNGIYKNGKKVLSGYINDNTKIVFRSESSRLLFIIQITNEMWSFDESGEQMFQKMINSFFPKIFNKWKDIETHHSITIAFAISMDMSTSSYKDLKPGQRIKNTTDYYRIVVDQVSVIYWVEIMESLRKEFMEITRELLSRKSDDKKDNELSVIKGRFAPVIKSNILELINFAATTIVDPFRQLDLRHTSTHVMIISPGKGLYDVDYDLLQLSCKKLLSLELTMDLICLSNPPLHVVPLFRYIDYENKLHHCIPPWLNIFFWNDKTKDTNKWTPRCQIYDLQMMGLTDTELVQELELDYLNPSDDINDLQTFLKDYDRDIFLPISTANFKAENISSDPDEEDLKELKKINDKTTTIHKSSTSRNTLTKSQRTNSEENNSIRSRKGDTIIKDPQFVGKISNSSRNNPPYDLSDKSTFEKQFKPKTTFHPSAMIKKTPENMKKLTNPVFQQQYFDIQTDNGLTGNSKNLLIKNTKYLTPIIDEPQTPLVTGNLYRTRFESQSNDNELNENSKLPERGGGTDERRNVSAADTLKDVTKKSSIKDFTQRIFTKFLATTKQSNFNSDGINSSAITEDAVLISDDTDGKTNNNNDFAVYPSSVADGDVSGDNQHRLNNKDSFTSILKPIPRPQLGVKIFKSDINNLSSNENVNSETKQNLLGTRNTINRKQFTASPHFTSSTKNSVSNHSRFIKFDSMDDWIEILEDSIPSYSFLGDDLLPTRWRDVWPKNVFRKYSKWKSFTSPAELPITLKRFPSKYELENNFMLRNHSVTQNWEQEQYKLTTKDLLRNMIYLRLLVGFQICTSSTIEEVESARKGDRDVFAIHKYLRGDLTGTFKIYMLMGSEIHRLHYDNSGTINVERYIEKSERNVFDQVPSYTSFVKTRYDSNYRKTDVDPIHTKRSEFNWNLLDQLLAGYSDPYLYDEWHGFRSKYVILPAEIPSNTFSMVVNGKNETLTTEEIRVEGLRKLIASITRLKLLSVEESKIQKDRKTEIQPEVIFYTGSLFDFLNEQQAQLDSSTLNFKDSIFGDVTKKLNKNIDLKNLAQELQMGENKLNLVTRKWHWKRHANCFVGSEMVNWLIRNFSDIDTRSTAISYGQKLMNDGLFIHVLDKHSFLDGNYFYQISPEFIINMNTVERTNSKNSNTSDNNTLKKTTSRNSTESNLTPLSMRNKVSTMDDDSTQLANTTSANSYKEKKTVVLSNSMLINVDPSSKSYKEELCTVHFDRVHNPEHCFHIRLEWLTTTPKLIDNMLGNWARICEKYGLKLIEIPWNELCTIPSVDPFHTFVQLHLVINPWEDPEFNDPELFAVSKFYYHIHLLKMSGFLLDNRASRFFQRDDADFEIMYSWGKPQFKYAQYIHTTGAYIAEMRENGNIFLAPNNVYMSRVNRANVISKTRSSPTFTVDSRKVVIEFSRTCYSYAKLRAVFLDAKEKWLSNKTVED
What are the official names of this protein?
Vacuolar membrane-associated protein IML1.
What is the protein family that this protein belongs to?
Belongs to the IML1 family.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein.
Protein: RL10_CITFR
Sequence: MALNLQDKQAIVAEVSEVAK
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: Y1280_MYCBP
Sequence: MDGTPGHDDMPGQPAPSRGESLWAHAEGSISEDVILAGARERATDIGAGAVTPAVGALLCLLAKLSGGKAVAEVGTGAGVSGLWLLSGMRDDGVLTTIDIEPEHLRLARQAFAEAGIGPSRTRLISGRAQEVLTRLADASYDLVFIDADPIDQPDYVAEGVRLLRSGGVIVVHRAALGGRAGDPGARDAEVIAVREAARLIAEDERLTPALVPLGDGVLAAVRD
What are the official names of this protein?
Putative O-methyltransferase BCG_1280c.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
Protein: QUEC_BURO1
Sequence: MIRTDAKDGALVLFSGGQDSATCVAWALERYQTVETLGFDYGQRHRVELECREGVREALKHRFPAWSDRLGDDHMIDLSVLGAISDTAMTRTIEIETTANGLPNTFVPGRNLMFMTIAAAIAYRRGLRVLVGGMCETDFSGYPDCRDDTMKALQVALNLGMDTRMVLETPLMWLDKAQTWQLAEQLGGEALVELIRVETHTCYVGERAELHDWGFGCGECPACKLRKRGYEAYLKGERVTEAPL
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: RL14_TOLAT
Sequence: MIQMQSMLDVADNSGARSVMCIKVLGGSHRRYAGVGDIIKVSIKEAIPRGKVKKGDVYNAVVVRTRKGVRRQDGSLIRFDRNAAVLLNNQHQPIGTRIFGPVTRELRNDKFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: Y5815_ARATH
Sequence: MRLSLWGSLLFFSFFVKHLTSLDPNTDAYHLSSFFSAMRLPNSPQAHTFSSLCSWPGVVVCDSSENVLHISASGLDLSGSIPDNTIGKMSKLQTLDLSGNKITSLPSDLWSLSLLESLNLSSNRISEPLPSNIGNFMSLHTLDLSFNSISGKIPAAISNLVNLTTLKLHNNDFQFGVPPELVHCRSLLSIDLSSNRLNESLPVGFGSAFPLLKSLNLSRNLFQGSLIGVLHENVETVDLSENRFDGHILQLIPGHKHNWSSLIHLDLSDNSFVGHIFNGLSSAHKLGHLNLACNRFRAQEFPEIGKLSALHYLNLSRTNLTNIIPREISRLSHLKVLDLSSNNLTGHVPMLSVKNIEVLDLSLNKLDGDIPRPLLEKLAMMQRFNFSFNNLTFCNPNFSQETIQRSFINIRNNCPFAAKPIITKGKKVNKKNTGLKIGLGLAISMAFLLIGLLLILVALRVRRKSRTWATKLAINNTEPNSPDQHDSTTDIKQATQIPVVMIDKPLMKMTLADLKAATFNFDRGTMLWEGKSGPTYGAVLPGGFRAALKVIPSGTTLTDTEVSIAFERLARINHPNLFPLCGYCIATEQRIAIYEDLDMVNLQSLLHNNGDDSAPWRLRHKIALGTARALAFLHHGCIPPMVHGEVKAATILLDSSQEPRLADFGLVKLLDEQFPGSESLDGYTPPEQERNASPTLESDVYSFGVVLLELVSGKKPEGDLVNWVRGLVRQGQGLRAIDPTMQETVPEDEIAEAVKIGYLCTADLPWKRPTMQQVVGLLKDISPNY
What are the official names of this protein?
Probably inactive leucine-rich repeat receptor-like protein kinase At5g58150.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: YGBN_ECOLI
Sequence: MSTITLLCIALAGVIMLLLLVIKAKVQPFVALLLVSLLVALAAGIPAGEVGKVMIAGMGGVLGSVTIIIGLGAMLGRMIEHSGGAESLANYFSRKLGDKRTIAALTLAAFFLGIPVFFDVGFIILAPIIYGFAKVAKISPLKFGLPVAGIMLTVHVAVPPHPGPVAAAGLLHADIGWLTIIGIAISIPVGVVGYFAAKIINKRQYAMSVEVLEQMQLAPASEEGATKLSDKINPPGVALVTSLIVIPIAIIMAGTVSATLMPPSHPLLGTLQLIGSPMVALMIALVLAFWLLALRRGWSLQHTSDIMGSALPTAAVVILVTGAGGVFGKVLVESGVGKALANMLQMIDLPLLPAAFIISLALRASQGSATVAILTTGGLLSEAVMGLNPIQCVLVTLAACFGGLGASHINDSGFWIVTKYLGLSVADGLKTWTVLTTILGFTGFLITWCVWAVI
What are the official names of this protein?
Inner membrane permease YgbN.
What is the protein family that this protein belongs to?
Belongs to the GntP permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CALB_PENDC
Sequence: MDEVTRTAQRSPSITETHAGETKLAGPGEKEGDVESPVDPSADSEQNRQQITGLQLFAILASVTLSAFLMLLDGSIIGVAIPNITSQFHSIDDIGWYTAAYQLASAALQPLSGKIYSSFSTKWTYLFFFGLFELGSLICGVANSSSMLIGGRAVAGLGSSGLLNGGMTIIAGAVPLEKRPVYTGIYLGISQLGIVCGPLIGGALTEYTTWRWCFYINLPVGAVTAILLLFLQVPELTEKPRFTFALVRRVIPELDLIGFTLFAPAAIMVLLALYYGGNDFPWDSSQVIGLFCGAGVTIIVFALWERRVGDRAMIPPSMVSHRIVYTSAINGAALVASILVAAQYLPIYFQGVRGYGPAMSGVNTLPGILSQLLTVILSGVLVQKVGYYLPFAAAGSAISAVGNGIVTLFSPTTPTAKWIGYQIVLGSGRGIGMQMGIIAIQNLLPPEKISVGIAFMIFCQNFAGAIFVVVGEVIFTQQLVKQIQAHAPSVKVDAALAAGASSSSLRALVPPGSPELQGVLLAFSNSVDRVFYLLMSLSLAGFVAAFGMGWVDTRKKNKSETE
What is the function of this protein?
MFS-type transporter; part of the gene cluster that mediates the biosynthesis of calbistrin A and related compounds.  Calbistrin A is a secondary metabolite with an interesting structure that was recently found to have bioactivity against leukemia cells.  It consists of two polyketides linked by an ester bond: a bicyclic decalin containing polyketide and a linear 12 carbon dioic acid structure (PubMed:30598828).  Required for the secretion of calbistrin A and calbistrin C, as well as of related compounds decumbenone A, B and C (PubMed:30598828).
What are the official names of this protein?
MFS-type transporter calB, Calbistrin biosynthesis cluster protein B.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CH60_POLNS
Sequence: MAAKDVVFGDSARTKMVEGVNILANAVKTTLGPKGRNVVIERSFGGPIITKDGVSVAKEIELKDKLQNMGAQMVKEVASKTADIAGDGTTTATVLAQSIVREGMKYVVSGYNPLDLKRGIDKAVTAAIEELAKISKPCTTTKEIAQVGSISANSDQSIGQRIAEAMEKVGKEGVITVEDGKSLEDELEVVEGMQFDRGYLSPYFINQPEKQVAVLESPYVLLFDKKIANIRDLLPVLEQVAKSGRPLLIIAEDVEGEALATLVVNNIRGIIKTCAVKAPGFGDRRKAMLEDIAILTGGIVIAEEIGLTLEKTTLEHLGQAKRLEVGKENTIIIDGAGDAKAIEARVKNIRVQVEEATSDYDKEKLQERVAKLAGGVAVIRVGAATEVEMKEKKARVDDALHATRAAVEEGIIPGGGVALIRAMQGIKGLKGDNADQDAGISIVLRAMQEPLRTIVSNAGEDAGVVVNAVQASKGNNGYNAATGEYGDLVAQGVIDPTKVTKAALVNAASVAGLLLTTDCAISEAPKDESAGGGMPDMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C3H68_ARATH
Sequence: MMKKTKKGRVSWASDSMLCQVKLFLSDDCPVKVASNLPPGFEATDYATKRIISHIPRIKWKRPPLFVLDDALLVGSGGKSIETRSENLRISKVLEAFYPHRSVIPSRPSLTLAVEEEHYDDGKTPNIPLTHVEDERDAAAESSHSFEAPAAVSGLGPELSLLASAALSALTKEQGSQVDPDLLVKLLSDPKIVENLINGMKGKPLETANNSLNTDITEPRLAPQHVTSTTMDRNPPPMPGNVAPHNVPVSVQSSATDPPLPKPNQPMSSALSMNLTLQKPTPVVHNYPLSSGIKVEDSYTAAPLKPSTGDDVVVSEQKTQLLFPCSSWNMNKVPESARTETDPQIRNGNTNRDDQVSAKPVKDLDYFKNLIREHGAVKPATTETNNYKGRVDHKKIVKVRIQKPCMYFNRPKGCRMGESCLYLHDSSKRLWTDVAPPHFPRAKRLKFGS
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 68, AtC3H68.
Protein: DPO3A_STRP8
Sequence: MFAQLDTKTVYSFMDSLIDLNHYFERAKQFGYHTIGIMDKDNLYGAYHFIKGCQKNGLQPVLGLEVEILYQERQVLLNLIAQNTQGYHQLLKISTAKMSGKLHMDYLCQHLEGIAVIIPSKGWSDTLVVPFDYYIGVDQYTDLSHMDSKRQLIPLRTVRYFAQDDMETLHMLHAIRDNLSLAETPVVESDQELADCQQLTTFYQTHCPQALQNLEDLVSGIYYDFDTNLKLPHFNRDKSAKQELQDLTEAGLKEKGLWKEPYQSRLLHELVIISDMGFDDYFLIVWDLLRFGRSKGYYMGMGRGSAAGSLVAYALDITGIDPVQHDLLFERFLNKERYSMPDIDIDLPDIYRSEFLRYVRNRYGSDHSAQIVTFSTFGPKQAIRDVFKRFGVPEYELTNLTKKIGFKDSLATVYEKSISFRQVINSRTEFQKAFAIAKRIEGNPRQTSIHAAGIVMSDDTLTNHIPLKSGDDMMITQYDAHAVEANGLLKMDFLGLRNLTFVQKMQEKVAKDYGCQIDIAAIDLEDPQTLALFAKGDTKGIFQFEQNGAINLLKRIKPQRFEEIVATTSLNRPGASDYTTNFIKRREGQEKIDLIDPVIAPILEPTYGIMLYQEQVMQIAQVYAGFTLGKADLLRRAMSKKNLQEMQKMEEDFIASAKHLGRAEETARGLFKRMEKFAGYGFNRSHAFAYSALAFQLAYFKAHYPAVFYDIMMNYSSSDYITDALESDFQVAQVTINSIPYTDKIEASKIYMGLKNIKGLPRDFAYWIIEQRPFNSVEDFLTRTPEKYQKKVFLEPLIKIGLFDYFEPNRKKILDNLDGLLVFVNELGSLFSDSSFSWVDTKDYSATEKYSLEQEIVGVGMSKHPLIDIAEKSTQTFTPISQLVKESEAVVLIQIDSIRIIRTKTSGQQMAFLSVNDTKKKLDVTLFPQEYAIYKDQLKEGEFYYLKGRIKERDHRLQMVCQQVQMAISQKYWLLVENHQFDSQISEILGAFPGTTPVVIHYQKNKETIALTKIQVHVTENLKEKLRPFVLKTVFR
What is the function of this protein?
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.  The alpha chain is the DNA polymerase (By similarity).
What are the official names of this protein?
DNA polymerase III subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. DnaE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBN_NOSS1
Sequence: MEPAIVLIISVGAALVAVTGYGIYTAFGPPSRELSDPFEDHED
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: HLD_STAAU
Sequence: MAQDIISTIGDLVKWIIDTVNKFTKK
What is the function of this protein?
Lyses erythrocytes and many other mammalian cells.
What are the official names of this protein?
Delta-hemolysin, Delta-lysin, Delta-toxin.
What is the protein family that this protein belongs to?
Belongs to the delta-lysin family.
What are the subcellular locations of this protein?
Secreted. Host cell membrane. Note=In infected cells, it is found in the membrane.
Protein: CLSA_PSEU2
Sequence: MDYHDPYFFGYVLGFIHLLGTGAAIHALLTVRTSQGAIAWAMPLLFIPYFTLLPYLVFGRSSFDAYIKARRQANQEMRIAIGDLNWRPWMEEAVAARRSEAYAALRAMPKLGNMPALANNKVKLLINGEETFGAIFQAIREAKKTILVQFFIIHDDKLGRELQSLLLEKAAEGVAIFVLYDRIGSHALPGAYIDKLRDGGVQIKAFATRGGWLNRFQINFRNHRKIVVVDGLKGYIGGHNVGDEYMGLKPPLAPWRDTHVQVIGPVVACLQESFAEDWFWATRELPPLSLPDEFPEDGVLCQLLTSGPADAQETCSLFFVEAIHAAEERVWITSPYFIPDEAVTAALTLAVLRGVDVRLLLPSRPDHYVVYAASSLYAFDAVRAGVRVFRYEPGFLHQKVVLVDNEITAIGSANLDNRSFRLNFELMLLTVDSDFSSQVESMLTADFNLAREISVQESHETRRLHQLGMRVARLISPIL
What is the function of this protein?
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
What are the official names of this protein?
Cardiolipin synthase A, CL synthase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DICER_DANRE
Sequence: MAGLQLVTPASSPMGPFFGLPWQQEAIHDNIYTPRKYQVELLEAALEHNTIVCLNTGSGKTFIAVLLIKELSHQIRGENGKRTVFLVNAASSVAQQASTVRTHSDLQVGDYMSEDMTSWPEEMWNREMIENQVLVMTCHIFLHVLKNGVLPLSKINLLVFDECHLAITGHPYREIMKICEGCPSCPRILGLTASILNGKCDPCDLEEKIQNLEKILQSNAETATDLVVLDRYASQPREEVLDCGQYQDQSGLSERLLNELDEALNFLNDCNLSVHREDRDPTFISKQVLNDCRAVLTVLGPWCADKAAGIMVRELQKYIKHEQEELNRKFLLFTDTILRKIHALCEEHFSPASLDLKFVTPKVIRLLEILHEYKPFERQQFESVEWYNNRNQDNYVSWSDSEDDDEDEEAEAKEKTEANFPSPFTNILCGIIFVERRYTAVVLNRLIKEAGKQDPELAYISSNFITGHSIGKNQPRNKQMEVEFRKQEEVLRKFRAHETNLLIATSIVEEGVDIPKCNLVVRFDLPTEYRSYVQSKGRARAPVSNYIMLADSERTKTFQEDLKTYKAIEKILRNKCSKSAECNDFELEPVTDDDNVLPPYVLRSEDGGPRVTMNTAIGHVNRYCARLPSDPFTHLAPKCKTVEMNTGGYRSTLFLPINSPLRVPVTGPVMNCARLAEKAVALLCCEKLHKIGELDDHLMPVGKETVKYEEELDLHDEEETSVPGRPGSTKRRQCSPKAIPECLRGCYPVPEQPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPRIPHFPVYTRSGEVTISIELQKSGFSLSAEQLELITRLHQYIFSHILRLEKPALEFKPVEADSAYCVLPLNIVEDSNTLDLDFKFMEDIEKSEARIGIPNTQYTKQNPFIFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLSNVNQPLLDVDHTSSRLNLLTPRHLNQKGKALPLSSAEKRKAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHCLLTAEELRSQTAIDAGVGAQTLPPDFRYPNLDFGWKKSIDSKSFISCPSACMEEDDDHCKLGTSSDSNHTAPESCSMEVSQPPEGAPNTPDEKLETLTLPVTDLNKDCFPNLPNGTQADSDDLPHRSDVCQCSQLGPLERDLSTQTTTSVSVRPSPAGEPQPWPSDECTGRSSDLCDPHVKKPTSKHCPKSETATSTPAPSETSSEDCRSACAGPAWDSPKTLGPNPGLILQALTLSNASDGFNLERLEMLGDSFLKHAITTYLFCTYPDAHEGRLSYMRSKKVSNCNLYRLGKKKGLPSRMVVSIFDPPVNWLPPGYVVNQDKSSTDKWDSDENKDLANGKASDDEDEDDDDEPEEAEVEPSKEDVNVEDDLEYYYEHIRFIDSMLIGSGAFGKKISLQPTDPGYEWKAPKKAHNSHFSPDGGADEFDYSSWDAMCYLDPSKAGEEDDFVVGFWNPSEENCGTDIGKQSISYDLHTEQCIADKSIADCVEALLGCYLTSCGERAAQLFLCSLGLKVLPPEKQSSGGSAELQYGWLKIPPRCMFEHPDAERTLNHLISGFLNFESKINYTFKNKAYLLQAFTHASYHYNTITDCYQRLEFLGDAILDYLITKHLYEDPRQHSPGVLTDLRSALVNNTIFASLAVKYDYHKYFKAVSPELFHVIDDFVQFQLEKNEMQGMDSELRRSEEDEEKEEDIEVPKAMGDIFESLAGAIYMDSGMSLETVWQVYYPMMRPLIEKFSANVPRSPVRELLEMEPETAKFSPAERTYDGKVRVTVEVVGKGKFKGVGRSYRIAKSAAARRALRSLKANQPQVQNN
What is the function of this protein?
Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing.  Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs.  SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation.  Gene silencing mediated by siRNAs, also called RNA interference, controls the elimination of transcripts from mobile and repetitive DNA elements of the genome but also the degradation of exogenous RNA of viral origin for instance.  The miRNA pathway on the other side is a mean to specifically regulate the expression of target genes (By similarity).
What are the official names of this protein?
Endoribonuclease Dicer.
What is the protein family that this protein belongs to?
Belongs to the helicase family. Dicer subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CB5D1_MOUSE
Sequence: MPRRGLVAGPDLDNFQRRYFTPSEVAEHNQLEDLWVSYLGFVYNLTPLVEEFKGDLLLKPILEVAGQDISHWFDPQTRDIRKHIDPLTGCMRYRTPRGRFVHIPPPLPRSDWANDFGVPWWKGANYQVGRLSARTRNIRIINTLATQEHTLQVGAQESMWEILHRYLPYNAHAASYTWKYDGKNLNMDQTLEENGIRDEEEEFDYLNMDGKLHTPAILLYFNDDLTEL
What is the function of this protein?
Radial spoke stalk protein that binds heme under oxidizing conditions.  Required for the coordinated beating of multiple cilia maybe by functioning in a redox signaling pathway.
What are the official names of this protein?
Cytochrome b5 domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b5 family.
Protein: VXCL1_RCMVE
Sequence: MRLLTILALCCVAIWVVESIGIEVLHETICVSLRTQRIPIQKIKTYTIKEGAMRAVIFVTKRGLRICADPDAGWTKAAITTLDKKNKKNKQKFNTTTVIPTQVPVSTNETTTVYG
What is the function of this protein?
Chemoattractant for CD4-dendritic cells, but not for CD4+ dendritic cells, T-cells or B-cells.
What are the official names of this protein?
Viral Lymphotactin, Viral XCL1, vSCL1.
What is the protein family that this protein belongs to?
Belongs to the intercrine gamma family.
What are the subcellular locations of this protein?
Secreted.
Protein: KAD_NEIFL
Sequence: FITAAFGIPQISTGDMLRAAIKAGTPLGLEAKKIIDEGGLVRDDIIIGMVKERIAQDDCKNGFLFDGFPRTLAQAEAIVEAGVDLDAVVEIDVPDSVIVDRMSGRRVHLASGRTYHVTYNPPKVEGKDDVTGEDLIQRDDDKEETVKKRLAVYHEQTEVLVDFYSKLEGEHAPK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPP_ACIAC
Sequence: MDFILLAKAAVMGVVEGLTEFLPVSSTGHLILAGALLGFDDDKAKVFDIAIQTGAIFAVVLVYWQKIRETLVALPTQPRARRFALNVLIGFLPAVVLALIFGKAIKAHLFTPVVVASTFILGGFVILWAERRAPGAVRVDSVDDMTPLDALKVGLVQCLAMVPGTSRSGATIIGGMLLGLSRKAATDFSFFLAIPTLIGAGVYSLYKERHLLSMADLPLFAVGLLFSFVSAWLCVRWLLRYISTHSFVPFAYYRIAFGIVVLATAWTGWVHWGE
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VG07_BPST6
Sequence: MLYAFKLGRKLRGEEPLYPEKGGKGGSSSSGAKEAARATQYAADLQNQQFNRVMEQLAPYAAAGLPALQQIQQLSTLEGQNSALNQYYNSDQYKQLADQARYQSLNAAEATGGLGSTATSNQIASIAPTLGQNWLSGQMQNYGNLLNVGQSAAAGQASAGQNYANNAGNLAQQMAAIRSQGSGQSTLGSAISGGTSGALAGAGLAGMLGASTPWGAGIGAGIGLLGSLF
What is the function of this protein?
Component of the phage injection machinery.  Required for injection of the phage DNA into the host (By similarity).
What are the official names of this protein?
DNA transfer protein gp7.
What is the protein family that this protein belongs to?
Belongs to the podoviruses gp7 family.
Protein: DATPH_BPSHA
Sequence: MDKLNIRDILRAQDVTRWQIVRTKKQSVAEHTFAVQAVLMRLVPLLISTYTAPMKVGFEERLLCECIMGAFWHDIPEVITGDIASPVKRLIRDGGDITPLDDLEKKVDPAFIKCYTAAKPLTLAIIKCADLMEMVYHLNEYGDQRANSHSWRVQHGINNAFHEHIHNCSENFPAFKWDVAHGLLIEMLDPSQETDIDSIVNGI
What is the function of this protein?
Catalyzes the hydrolysis of dATP, dADP and dAMP into dA (PubMed:33926954).  This step is essential for Z-genome synthesis (containing aminoadenine instead of adenine).  Specifically removes dATP and its precursor dADP from the nucleotide pool of the host, preventing the incorporation of A into the phage genome and favoring the integration of the Z-base into the viral genome (PubMed:33926954).
What are the official names of this protein?
dATP triphosphohydrolase, dATPase.
What is the protein family that this protein belongs to?
Belongs to the Caudovirales dATP triphosphohydrolase family.
Protein: IPYR_XYLFT
Sequence: MGLELVNAGNNLPEEINVIIEIPKDSEPVKYEVDKASGAIFVDRILSTPMRYPCNYGYVPNTLCGDGDPVDVMVVLPLPLVPGSVVRCRPVGVLQMKDEAGNDEKLLAVPVSKIFSGYSHIEDINQVSAHWLERIGHFFEHYKDLEKGKWVEIDGWGNATTAKQILTNAVQRYKDTLP
What is the function of this protein?
Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
What are the official names of this protein?
Inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDD_STRPN
Sequence: MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFKGVLMGLARILRCHPWSKTGKDPVPDRFSLKRNQEGE
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: LS14A_XENTR
Sequence: MSGGTPYIGSKISLISKAEIRYEGILYTIDTENSTVALAKVRSFGTEDRPTDRPIPPRDEVFEYIIFRGSDIKDLTVCEPPKPQCSLPQDPAIVQSSLGSSSASSFQSVSSYGPFGRMPTYSQFSTSPLVGQQFGAVGSSLTSFGAETTSSTSLPPSSTVGSSFTQEARTLKTQLSQGRSTSPLDSLRKSPTIEQAVQTASASHAPSAAPVGRRSPVLSRPLPSSSQKTGESSEQRKGELHKTQRPDTEQLRNDNRHDPNKRQPASSAPQPRRGRGGNRGGRGRFGVRRDGPMKFEKDFDFESANAQFNKEEIDREFHNKLKLKDDKPEKPVNGEDKTDSGVDTQNSEGNAEEDDVLAGGVCYYDKTKSFFDNISCDDNRDRRQTWSEERRINAETFGLPLRSNRGRGGFRGRGGGMGFRGGRGRGERRGPPGGGGFGSSRGYRGGSRGGRGGREFAEYEYRKDNKVAA
What is the function of this protein?
RNA-binding component of messenger ribonucleoprotein complexes (mRNPs), storage particles that mask maternal mRNAs from the translational apparatus during oocyte maturation.  Acts as a repressor of mRNA translation.  Probably involved in the storage of translationally inactive mRNAs in the cytoplasm in order to prevent their degradation.
What are the official names of this protein?
Protein LSM14 homolog A, RNA-associated protein 55A, RAP55A.
What is the protein family that this protein belongs to?
Belongs to the LSM14 family.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Cytoplasm, Stress granule. Note=Localizes to cytoplasmic particles in stage VI oocytes and eggs.