PharMolix/UniProtQA huggingface dataset:
Protein: KATG1_BURCH
Sequence: MSNETKCPFNHTAGSGTTNKDWWPNQLNLNVLHRHSALSDPMDPDFDYAEAFKKLDLAAVKQDLHALMTTSQDWWPADFGHYGGLFVRMAWHSAGTYRTADGRGGAGGGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGRNISWADLLILTGNVALESMGFKTFGYAGGRADTWEPDDVYWGSEKIWLELSGGPNSRYTGKRELESPLAAVQMGLIYVNPEGPDGNPDPVAAAHDIRETFARMAMNDEETVALIAGGHTFGKTHGAGPASNVGPEPEAAGLEEQGLGWKSTFGTGKGKDTITSGLEVTWTSTPTKWSNDFFKHLFSYEWELTKSPAGAHQWVAKDAGEVIPDAYDASKKHRPTMLTTDLSLRFDPAYEKISRRFYENPAEFADAFARAWFKLTHRDMGPRARYLGPEVPAEHLLWQDPIPAVDHPLIDAADVAALKAKVLATGLSVSQLVSTAWASAATFRGSDKRGGANGARIRLAPQKDWEVNQPAALATVLETLEGVQKAFNDAQTDGKKVSLADLIVLAGAAGVEQAAKNAGIAISVPFAPGRMDASQEETDVDAMAVLEPVADGFRNYLKSAYKTPAEALLVDKAQLLTLTAPEMTVLVGGLRVLGANVGDSKHGVFTDRPGTLSNDFFANLLDMGTEWKPVSAANDVFEGRDRATGAVKWTGTRVDLIFGSHSQLRALAEVYGSADAQEKFVRDFVAAWNKVMNLDRFDLA
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase 1, CP 1, Peroxidase/catalase 1.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: Y1514_LACDB
Sequence: MSKRPAFPGMGGMNMQQMMKQAKKLQEQMAKEQENITTQEFTGKAADDMVVATFTGDRTLKSLFIKPEAIDPDDPDMLEDLVIDAVNKGLKQIDQATQQSLGKYTKGLM
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein LBUL_1514.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: ARC_FRASN
Sequence: MSGPRSGSGSGGSTGRPGDADSQRSAYEKEVHELTTQVTFLEEEVAMLRRRLSESPRQVRVLEERLAQVQVELQTATGQNDKLVATLREARDQIISLKEEVDRLAQPPSGYGVFIRGYDDGTVDVFTQGRKLRVTVSPNVEADVLQPGQEVMLNEALNVVEVRAFERQGEIVLLKEVLESGDRALVIGHTDEERVVMLAQPLLDGPIRAGDSLLIEPRSGYAFERIPKSEVEELVLEEVPDIGYEQIGGLKGQIESIRDAVELPFLYKELFLEHKLKPPKGVLLYGPPGCGKTLIAKAVANSLAKKVEAQTGQGSGRAFFLNIKGPELLNKYVGETERQIRLVFQRAREKASEGMPVIVFFDEMDSIFRTRGSGVSSDVENTIVPQLLSEIDGVEQLENVIVIGASNREDMIDPAILRPGRLDVKIKVERPDAEAAKDIFAKYVLPELPLHADDLAEHGGNREATCQGMIQRVVERMYAESEENRFLEVTYANGDKEVLYFKDFNSGAMIENIVARAKKMAVKDLIESGVRGLRMQHLLSACLDEFKENEDLPNTTNPDDWARISGKKGERIVYIRTLVTGTKGTEAGRSIDTIANTGQYL
What is the function of this protein?
ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle.  May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis.  Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
What are the official names of this protein?
Proteasome-associated ATPase, AAA ATPase forming ring-shaped complexes, ARC, Proteasomal ATPase.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
Protein: RS9_MYCA1
Sequence: MTETTEALENPDNPDAETAAAEVTEAPVEAVPAESYVFERPIQTVGRRKEAVVRVRLVPGTGKFNLNGRTLEGYFPNKVHQQLIKAPLVTVDRVDSFDIYAHLHGGGPSGQAGALRLGIARALILASPDDRPALKKAGFLTRDPRATERKKYGLKKARKAPQYSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: NU4LM_PONPY
Sequence: MPLIYMNITLAFTMSLLGMLVYRSHLMSSLLCLEGMMLSLFIMITLMTLNTHSLLANIMPITMLVFAACEAAVGLALLASISNTYGLDYVNNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: VL1_HPV42
Sequence: MSVWRPSDNKVYLPPPPVSKVVSTDEYVQRTNYFYHASSSRLLVVGHPYYSITKRPNKTSIPKVSGLQYRVFRVRLPDPNKFTLPETNLYNPETQRMVWACVGLEVGRGQPLGVGISGHPLLNKLDDTENAPTYGGGPGTDNRENVSMDYKQTQLCLVGCKPAIGEHWGKGTACTPQSNGDCPPLELKNSFIQDGDMVDVGFGALDFGALQSSKAEVPLDIVNSITKYPDYLKMSAEAYGDSMFFFLRREQMFVRHLFNRAGAIGEPVPDELYTKAANNASGRHNLGSSIYYPTPSGSMVTSDAQLFNKPYWLQQAQGHNNGICWGNQLFLTVVDTTRSTNMTLCATATSGDTYTAANFKEYLRHAEEYDVQFIFQLCKITLTVEVMSYIHNMNPNILEEWNVGVAPPPSGTLEDSYRYVQSEAIRCQAKVTTPEKKDPYSDFWFWEVNLSEKFSTDLDQFPLGRKFLLQAGLRARPKLSVGKRKASTAKSVSSAKRKKTHK
What is the function of this protein?
Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter.  The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins.  Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment.  This binding mediates a conformational change in the virus capsid that facilitates efficient infection.  The virion enters the host cell via endocytosis.  During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus.  The virion assembly takes place within the cell nucleus.  Encapsulates the genomic DNA together with protein L2.
What are the official names of this protein?
Major capsid protein L1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: MTNN_THEMA
Sequence: MILVLGVFKIEVEPMLKEMEVLEKGRLLKRYYQRGVVGRNEVVVSYGFIGKVEAALVTQAFLDRFNIDAVFLTGNAGGLEGVEVGDVVIGDSYVEYDFETALGDEGIIVSGSEDLEDKVIAYSNREIKTGLIASGDAFVTVKEKAEEIKRRTGALCVDMDSAAVAKVCYENEKKFLAIKTIVDICGRETEEEFRKNYERYGFLSNLILLDVLKKCVF
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: RS27A_RAT
Sequence: MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAKKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVDENGKISRLRRECPSDECGAGVFMGSHFDRHYCGKCCLTYCFNKPEDK
What is the function of this protein?
Component of the 40S subunit of the ribosome.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
Ubiquitin-40S ribosomal protein S27a, Ubiquitin carboxyl extension protein 80.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
What are the subcellular locations of this protein?
[Ubiquitin]: Cytoplasm. Nucleus.
Protein: PUR9_CALS8
Sequence: MTKKAIISVYNKDGILEFAKELKNLGYEIISTGGTMKYLKENRIDVINISDVTNFPEILDGRVKTLHPNIHAGILAIKDNEEHVKTLNDLNISTIDMVVVNLYPFKETIFRENVAFEDVIENIDIGGPTMLRAAAKNFKYITVIIDPADYGLVLKEIKENGDVSFETRFYLATKVFEYTAYYDSMIFNYFKYIRGDKSFPDYLTVPLETVQKLRYGENPHQQASFYKITLPFIEKSNIANAEQLHGKDLSYNNILDSDSAIELLKEFDEPTCVAIKHNNPCGVASGDNIFEAYKKVYNSDPVSIFGGIVAFNRKVDRQTAEELKKIFLEIVIAPDFDEDALSLLSTKKDLRILKLLTLDKTDVYYDVKSVNGGMLVQEKDRKLLNEDYQVVTERRPTEKEIEDLIFAWKVVKHVKSNAIVIAKDKMTLGIGMGQTNRIWAVEHAISRSRFDLNGAVLASDAFFPFSDSVEAAGKAGITAIIQPGGSIRDKESIDAANKYNIAMIFTGIRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: CPPM_ARATH
Sequence: MSMLMAVKTTSLCCSSLNLTASPTFRRNPRAARLVNPTARIQTRFHRLIEEQGIVLMPGCYDALSAAIVQQTGFSAGFISGYALSASLLGKPDFGLLTPPEMAATARSVCASAPNIPIIADADTGGGNALNIQRTVKDLIAAGAAGCFLEDQAWPKKCGHMRGKQVIPAEEHAAKIASARDAIGDSDFFLVARTDVRATSAKSGLEDAIARVNLYMEAGADASFVEAPRDDDELKEIGKRTKGYRVCNMIEGGVTPLHTPDELKEMGFHLIVHPLTALYASTRALVDVLKTLKENGSTRDHLQKMATFEEFNSLVDLDSWFELEARYSNLRNALGTTKS
What are the official names of this protein?
Carboxyvinyl-carboxyphosphonate phosphorylmutase, chloroplastic, Carboxyphosphonoenolpyruvate phosphonomutase, CPEP phosphonomutase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate lyase/PEP mutase superfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SUCC_NEOSM
Sequence: MNIHEYQAKEILRVCGVPTPAGFLVQEDTETSEIAKSLARLGGKVFAVKAQIHAGGRGKAGGVVICRSVEEAIDNTKKMLGMNLVTHQTSPAGQKVRKVYIEAGQSILKEYYLSMVVDRENAKVAIIASEEGGMDIEEIARSTPEKIKKVFVDLSIGISDFHARKIGFELGLSLAQIKQFTPLVKKLYALFVTRDASQVEINPLIANSKGEFIALDAKLNFDDNALYRHPDTLELRDLYEEDPKEIEAAKYNLNYIKMEGGIGCMVNGAGLAMATMDIIKYYGASPANFLDVGGGANLEQVTNAFKIISSDKHVAGILVNIFGGIMRCDIIAEGIVAAAKDIGLTMPLVVRLSGTNYSAGIKIIEGSGLNIVTASELDDAAQKIVKLTRKEI
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: SODF_ECO57
Sequence: MSFELPALPYAKDALAPHISAETIEYHYGKHHQTYVTNLNNLIKGTAFEGKSLEEIIRSSEGGVFNNAAQVWNHTFYWNCLAPNAGGEPTGKVAEAIAASFGSFADFKAQFTDAAIKNFGSGWTWLVKNSDGKLAIVSTSNAGTPLTTDATPLLTVDVWEHAYYIDYRNARPGYLEHFWALVNWEFVAKNLAA
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Fe].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: UL119_HCMVM
Sequence: MCSVLAIALVVALLGDMHPGVKSSTTSAVTSPSNTTVTSTTSISTSNNVSSAVTTTVQTSTSSASTSVIATTQKEGHLYTVNCEASYSYDQVSLNATCKVILLNNTKNPDILSVTCYARTDCKGPFTQVGYLSAFPSNDKGKLHLSYNATAQELLISGLRPQETTEYTCSFFSWGRHHNATWDLFTYPIYAVYGTRLNATTMRVRVLLQEHEHCLLNGSSLYHPNSTVHLHQGDQLIPPWNISNVTYNGQRLREFVFYLNGTYTVVRLHVQIAGRSFTTTYVFIKSDPLFEDRLLAYGVLAFLVFMVIILLYVTYMLARRRDWSYKRLEEPVEEKKHPVPYFKQW
What is the function of this protein?
Serves as a receptor for the Fc part of human IgG.  May thus be involved in interfering with host Ig-mediated immune responses (By similarity).
What are the official names of this protein?
Viral Fc-gamma receptor-like protein UL119, gp68.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein.
Protein: ECCD5_MYCMM
Sequence: MTAVADAPQAELEGVSSPRAVVVGIMAGEGVQIGVLLDANAPVSVMTDPLLKVVNSRLRELGESTLEAAGRGRWALCLIDGSPLRATQSLTEQDVYDGDRLWIRFIPDTEHRSQVIEHISTAVASNLSKRFASIDPVVAVQVGAGMVGTGVILASGVLGWWRWHHNTWLTTIFASVIAVLVLMVAMMLLMRATTDADRRVADIMLVSGLAPLTVAAASAPPGSVGSPQAVLGFGVLSIAAALALRFTGRRLAIYTAIVTICGLTTLASLSRMVAATSAVTLFATMLLICVVMYHASPALSRRLSGIRLPVFPSATSRWVFEARPDLPTTVAVAAGGPPVLEGPASVRDVVLQAERARSFLSGLLVGLGVLMVVSLTSLCNPHTSERWLPLMLAGFTSGFLMLRGRSYVDRWQSITLAVTAVIVVAAVSVRYALVLSSPLSVSIVASLLVLLPAAGMTAAAVVPNTIYSPLFRKFVEWTEYLCLMPIFPLAFWLMNVYAAIRYR
What is the function of this protein?
Part of the ESX-5 specialized secretion system, which is responsible for the secretion of EsxN and a number of PE_PGRS and PPE proteins (PubMed:19602152, PubMed:22925462).  This component is essential for ESX-5 complex stability and secretion (PubMed:22925462).
What are the official names of this protein?
ESX-5 secretion system protein EccD5, ESX conserved component D5, Type VII secretion system protein EccD5, T7SS protein EccD5.
What is the protein family that this protein belongs to?
Belongs to the EccD/Snm4 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS8_CLOAB
Sequence: MSKFWNERVKKLEPYVPGEQPKDQKYIKLNTNENPYPPSPMVIEAIKKEADYKLKLYPDPNCDSLKRTIAEYYGISDKEVFVGNGSDEVLAFSFMTFFSPRKTVFFADITYSFYKVYANLLNLNCELIPLKEDFSLDLDNFCRCNGGVIIPNPNAPTAKYIGLSDIKKILDWNKDSVVIIDEAYIDFGGESAVKFIKDYKNLLIVQTLSKSRSLAGLRIGFAMGSPELIEGLSRVKNSINSYTLDRLAIVGAEAAFKDKEYFEDARRKIIATRERVSTELKQIGFKVIESKANFIFISHTTISAESIFNELRKRGILVRYFKTARIDNFLRVSIGTDKEMSEFMDKIKECIA
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: RIHA_ECOK1
Sequence: MALPILLDCDPGHDDAIAIVLALASPELDVKAITSSAGNQTPEKTLRNVLRMLTLLNRTDIPVASGAVKPLMRNLIIADNVHGESGLDGPALPEPTFAPQNCTAVELMAKTLRESEEPVTIVSTGPQTNVALLLNSHPELHSKIARIVIMGGAMGLGNWTPAAEFNIYVDPEAAEIVFQSGIPVVMAGLDVTHKAQIHVEDTERFRAIGNPVSTIVAELLDFFLEYHKDEKWGFVGAPLHDPCTIAWLLKPELFTTVERWVGVETQGKYTQGMTVVDYYYLTGNKPNATVMVDVDRQGFVDLLADRLKFYA
What is the function of this protein?
Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively.
What are the official names of this protein?
Pyrimidine-specific ribonucleoside hydrolase RihA, Cytidine/uridine-specific hydrolase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family. RihA subfamily.
Protein: SOX2_HUMAN
Sequence: MYNMMETELKPPGPQQTSGGGGGNSTAAAAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGGLLAPGGNSMASGVGVGAGLGAGVNQRMDSYAHMNGWSNGSYSMMQDQLGYPQHPGLNAHGAAQMQPMHRYDVSALQYNSMTSSQTYMNGSPTYSMSYSQQGTPGMALGSMGSVVKSEASSSPPVVTSSSHSRAPCQAGDLRDMISMYLPGAEVPEPAAPSRLHMSQHYQSGPVPGTAINGTLPLSHM
What is the function of this protein?
Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity).  Binds to the proximal enhancer region of NANOG (By similarity).  Critical for early embryogenesis and for embryonic stem cell pluripotency (PubMed:18035408).  Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity).  Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).  May function as a switch in neuronal development (By similarity).
What are the official names of this protein?
Transcription factor SOX-2.
What are the subcellular locations of this protein?
Nucleus speckle. Cytoplasm. Nucleus. Note=Acetylation contributes to its nuclear localization and deacetylation by HDAC3 induces a cytoplasmic delocalization (By similarity). Colocalizes in the nucleus with ZNF208 isoform KRAB-O and tyrosine hydroxylase (TH) (By similarity). Colocalizes with SOX6 in speckles. Colocalizes with CAML in the nucleus (By similarity). Nuclear import is facilitated by XPO4, a protein that usually acts as a nuclear export signal receptor (By similarity).
Protein: ASTD_BURO1
Sequence: MTELFIDGAWVAGSGPVFASRNPGTDAVAWQGESASAADVDRAVASARRAFAGWSALDFEARCEIVKRFAALLTERKEAIATAIGRETGKPLWEARTEVASMAAKVGISIQAYQERTGEKRQDMADGVAVLRHRPHGVVAVFGPYNFPGHLPNGHIVPALIAGNTVVFKPSELAPGVARATVEVWQEAGLPAGVLNLVQGEKDTGIALANHRQIDGLFFTGSSDTGTLLHKQFGGRPEIVLALEMGGNNPLVIGEVEDIDAAVHHTIQSAFLSAGQRCTCARRIFVPQGAFGDRFLARFADVTSKITADVFDADPQPFMGAVISARAAAKLVDAQARLVEQGAKPIVAMAQRDPRLGFVNAAIVDVTGVANLPDEEHFGPLAQVVRYATFDEAIERANDTAFGLSAGLLADDAKVWEHFRRTIRAGIVNWNRPTNGASSAAPFGGTGRSGNHRPSAYYAADYCAYPMASVESTQLTLPASLSPGLHF
What is the function of this protein?
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
What are the official names of this protein?
N-succinylglutamate 5-semialdehyde dehydrogenase, Succinylglutamic semialdehyde dehydrogenase, SGSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. AstD subfamily.
Protein: YB28_YEAST
Sequence: MEPFSPTICETVPLYPQWNGLIAGHLETSDISETFMSFVFYATTINVIIELKKLLILIINGGNTRGAITSRDIRYLTPFKICTCARFKKKKGSRNRNEIAHFSFRFRRFCKSLSRYTRVLLMFM
What are the official names of this protein?
Putative uncharacterized protein YBR178W.
Protein: RL20_SHEFN
Sequence: MPRVKRGVTARARHKKVLKLAKGYYGARSRTYRVAVQAVTKAGQYAYRDRRQKKRQFRQLWIARINAASRQNGLSYSRFINGLKKASIEIDRKILADIAVFDKVVFATLVEKAKEALTK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: PDAD_THEKO
Sequence: MSWTTPKRAFIGAATAEGGTKLNAFDNALLKLGIGNVNLVKLSSVIPAHIEWMEKVHDVPIGMLLPTVYAHIESDEPGMTISAALGVGISKNNEGGLIYEYSGYCTKEEAEEMVRKMVEEGFRQRGWELGEFKVASAEITVKDKPAAAIAVVVMFPY
What are the official names of this protein?
Pyruvoyl-dependent arginine decarboxylase, PvlArgDC.
What is the protein family that this protein belongs to?
Belongs to the PdaD family.
Protein: SIAT2_HUMAN
Sequence: MKPHLKQWRQRMLFGIFAWGLLFLLIFIYFTDSNPAEPVPSSLSFLETRRLLPVQGKQRAIMGAAHEPSPPGGLDARQALPRAHPAGSFHAGPGDLQKWAQSQDGFEHKEFFSSQVGRKSQSAFYPEDDDYFFAAGQPGWHSHTQGTLGFPSPGEPGPREGAFPAAQVQRRRVKKRHRRQRRSHVLEEGDDGDRLYSSMSRAFLYRLWKGNVSSKMLNPRLQKAMKDYLTANKHGVRFRGKREAGLSRAQLLCQLRSRARVRTLDGTEAPFSALGWRRLVPAVPLSQLHPRGLRSCAVVMSAGAILNSSLGEEIDSHDAVLRFNSAPTRGYEKDVGNKTTIRIINSQILTNPSHHFIDSSLYKDVILVAWDPAPYSANLNLWYKKPDYNLFTPYIQHRQRNPNQPFYILHPKFIWQLWDIIQENTKEKIQPNPPSSGFIGILIMMSMCREVHVYEYIPSVRQTELCHYHELYYDAACTLGAYHPLLYEKLLVQRLNMGTQGDLHRKGKVVLPGFQAVHCPAPSPVIPHS
What is the function of this protein?
Transfers sialic acid from the donor of substrate CMP-sialic acid to galactose containing acceptor substrates.  Has alpha-2,6-sialyltransferase activity toward oligosaccharides that have the Gal-beta-1,4-GlcNAc sequence at the non-reducing end of their carbohydrate groups, but it has weak or no activities toward glycoproteins and glycolipids.
What are the official names of this protein?
Beta-galactoside alpha-2,6-sialyltransferase 2, Alpha 2,6-ST 2, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 2, ST6Gal II, ST6GalII, hST6Gal II, Sialyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 29 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Protein: S1FA1_ARATH
Sequence: MDGEDFAGKAAAEAKGLNPGLIVLLVVGGPLLVFLIANYVLYVYAQKNLPPRKKKPVSKKKLKREKLKQGVPVPGE
What is the function of this protein?
DNA-binding protein that specifically recognizes a negative element (S1F) within the RPS1 promoter.
What are the official names of this protein?
DNA-binding protein S1FA1.
What is the protein family that this protein belongs to?
Belongs to the S1FA transcription factor family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DER_HALH5
Sequence: MSKPVIAIVGRPNVGKSTIFNRIVGERVAIVEDRPGVTRDRIYSHGEWLNREFNVIDTGGIEIGDEPLLVQMRAQAELAIKEADVIIFIVNGREGVTAADQEVAKLLFRSKKPVVLGVNKIDHPDMQEELYEFYSLGIGDPIPISGAHGLGLGDLLDACVEHFPEDEGDDYDEDTIRISLIGRPNVGKSSLVNAMLGEERVIVSNIPGTTRDAIDTAFSRDDQEYVLIDTAGMRKRGKVYESTEKYSVLRSLKAIERSDVVLVVLNGEEGIIEQDKKIAGYAHEAGRAIIIVVNKWDAVEKDDKTLHRFQQKIRDEFQFLDYAPVLFVSAKTKQRLQHVLPAVKKVSENHNLRVPTHVLNDLVMDAVAMNPTPTDHGKRLKINYVTQVAVGPPTFVFFVNDPELMHFSYARFLENRLRDTFEFEGTPIKIIARKKND
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: SYP_CLOPE
Sequence: MKMSNMLVGTLREVPAEAEIESHKLMLRAGLMRKMAAGIYNYMPLGLKVIENVKNIVREEMNNAGAQEFLASALIPAELWQESGRWDAYGAEMFRLKDRHNRDFCLGPTHEEVFTDIVRNEIKSYKQLPLNLYQIQTKYRDERRPRFGVMRSREFIMKDGYSFDKDQEGLDLAYEKMRKAYVNIFNRCGLDAKAVAADSGAIGGSGSAEFMVKSEVGEDDVVFCTACDYAANIEKAPSTPEHGEKEELMEVEKVETPAVKSIEDLAKFFECSPKKIAKTLIFQADDKVVAVVLRGDREANEVKIANAIGEVIELEMASEEAVKEATGAAVGFAGPMGIKVDMLLVDQEVANMYNFIIGANETDMHLKNVNYGRDFEGIVGDFRNVTIGEKCPECGKEITISRGTEVGHIFKLGTKYSESMGATFIDEDGKAKPFIMGCYGIGVTRTVASIIEQHNDENGIIWPLEVAPYHVSVIPANVKNEEQATKAEEIYNELRKMGVEALLDDRKERAGVKFKDSELMGIPMRITVGKMIGEGQVEFKLRNGGEVETLSIEEVYNRVREEFERANLSL
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OIG1_CAEEL
Sequence: MFSELRILRDILLLCFLSVGINAKSSHIEDLDFTDHTNGSPKISRSSYFKQDFRLGYKLKLFCESSGNPRPQIVWYHRGVEVNPDHNRTIRFSIHGDTVSSHLEVDPTSIGDKGEYECVATNLKGSRVKKFLTDYQY
What is the function of this protein?
Plays a role in neural development, where it temporally regulates synapse formation in the D-type inhibitory GABAergic motor neurons, dorsal D (DD) and ventral D (VD) motor neurons (PubMed:26387713, PubMed:26083757).  Controls the translocation of postsynaptic proteins, such as the acetylcholine receptor subunit acr-12, and presynaptic proteins, such as snb-1, along nerve cords to prevent premature synapse remodeling/formation (PubMed:26387713).
What are the official names of this protein?
Immunoglobulin domain-containing protein oig-1.
What are the subcellular locations of this protein?
Membrane. Secreted, extracellular space. Cell projection, dendrite. Cell projection, axon. Note=The non- secreted form shows punctate expression in dendrites and is also involved in synapse formation/remodeling. May also be secreted by coelomocytes.
Protein: PYRH_HAEIE
Sequence: MSQPIYKRILLKLSGEALQGEDGLGIDPAILDRMAVEIKELVEMGVEVGVVLGGGNLFRGAKLAKAGMNRVVGDHMGMLATVMNGLAMRDSLFRADVNAKLMSAFQLNGICDTYNWSEAIKMLREKRVVIFSAGTGNPFFTTDSTACLRGIEIEADVVLKATKVDGVYDCDPAKNPDAKLYKNLAYAEVIDKELQVMDLSAFTLARDHGMPIRVFNMGKPGALRQVVTGTEEGTTIC
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.