PharMolix/UniProtQA huggingface dataset:
Protein: PSAC_VITVI
Sequence: MSHSVKIYDTCIGCTQCVRACPTDVLEMIPWDGCKAKQIASAPRTEDCVGCKRCESACPTDFLSVRVYLWHETTRSMGLAY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: PROA_LACCB
Sequence: MDATTIDLEQMGRAAKTAAMTLGQLTTLQKNTGLLAMAAALETHADTILAANKADLAAASALPEKFVDRLALTKARIADMAAGVRQVATLDDPTAQTDRAWVNEAGLTIAQKRVPLGVVGMIYEARPNVTVDAAALTFKSGNAVILRGGKEALHSNLALATVLQDALAAKGLPRDAVQLITDPSRAVATQMMHLNGYIDVLIPRGGKGLIKAVVEQATVPVIETGAGNCHIYVDAHAQLQMAVAIVVNAKVQRPSVCNAAEKLLIHADVANEQLPVIAKALQDHGVELRGDERARAIVPSMHAATAEDWDTEYNDLIMAVKVVDSEEEAIQHINAHNTKHSEAIITDNYQNSQQFLQQVDAAVVYVNASTRFTDGYEFGFGAEIGISTQKLHARGPMGLAALTTIKYQVLGNGQIRKN
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQIG_BACSU
Sequence: MNPKYKPLFEPFTFKSGVTINNRIAVAPMTHYASNEDGTISEAELDYIIPRSKEMGMVITACANVTPDGKAFPGQPAIHDDSNIPGLKKLAQAIQAQGAKAVVQIHHGGIECPSELVPQQDVVGPSDVFDNGKQIARALTEEEVENIVKAFGEATRRAIEAGFDGVEIHGANGYLIQQFYSPKTNQRTDRWGGSDEKRLAFPLAIVDEVKKAASEHAKGAFLVGYRLSPEEPETPGLTMTETYTLVDALGDKELDYLHISLMDVNSKARRGADPTRTRMDLLNERVGNKVPLIAVGSIHSADDALAVIENGIPLVAMGREILVDPNWTVKVKEGREKQIETVIKGTDKEKYHLPEPLWQAIVNTQGWVPYKD
What are the official names of this protein?
Probable NADH-dependent flavin oxidoreductase YqiG.
What is the protein family that this protein belongs to?
Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.
Protein: DPYD_CAEBR
Sequence: MTPKPNTSNPNVGLPLLSKDSPDIESLLILNPKVQSKANAVPSAVTKKNKHNWKRNEEKGCGASCGESKLKNDFRDIKHTTLSERGALKEAMRCLKCADAPCQKSCPTQLDIKSFITSISNKNYYGAARAILSDNPLGLTCGMICPTSDLCVGSCNLQASEEGAINIGGLQQYACDVFKQMNVRQIVSKEVRENRNASHKEQIALIGCGPASISCASFLARLGYTDITIYEKRAYIGGLSSAEIPQFRLPYDVVDFEIQLARDVGVKIETNRSLCKEDITLDKLKSQGAAAVFIGIGNPEPKIDPLFEGLTIENGFYTSKNYLPAVAAASKPGMCGCKRTPLPTMRGRVVVLGAGDTAMDCATSALRCGASRVTIAFRKGFTGIRAVPEEMEAAKEEKCEFLPFSAPRKINVKDGRIVSIEFNKTEQDDNGKWYEDEEQIVILKCDYVISAFGSTLKEDTVLSALQPCKLNKWGGIEVDSTTQQTSEAWVFAGGDVAGVAETTVESVNDGKTLMDLTFKIQIAAWNMHRYIQAKHGNVLGETPELPKFFTPIDEVDISVDMCGVKFENPFGLASAPPTTSGPMCRRAFEQGWGFILTKTYGLDKDLVTNVSPRIVRGSTSGPLYGPNQGSFMNIELISEKSCEYWLQCIRELKRDHPTKIVVASIMCVYNKEDWIELATKSEAAGADILELNLSCPHGMGEKGMGLACGQSPEIVKEICRWVRACVKIPFFPKMTPNITDVREIARAARDGGASGVTATNTVSSLMHMKADGNAWPAIGNTKRTTYGGMSGSAIRPIAMKAVSSIANELDGFPIMATGGIESAETGLGFLMAGASVLQVCSAVQNQDFTVVEDYCTGLKALLYLSGAESLKEWDGQSPPVEKHQKGKPILLQGQKNMPFFGKFRDEREKLEALKLSESNLLDTDNYHFASRPDTQVARVPTVEDVIEHEVAIIDHDMCINCGKCYMTCNDSGYQAITFDAVTHQPHVTEDDCTGCTLCYSVCPIPECIQMVPRKGPWKAPKRGVKPTVEPGTPKVVKVDQRGRVILESTGGMQ
What is the function of this protein?
Involved in pyrimidine base degradation.  Catalyzes the reduction of uracil and thymine.  Also involved the degradation of the chemotherapeutic drug 5-fluorouracil (By similarity).
What are the official names of this protein?
Probable dihydropyrimidine dehydrogenase [NADP(+)], DHPDHase, DPD, Dihydrothymine dehydrogenase, Dihydrouracil dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the dihydropyrimidine dehydrogenase family.
Protein: GLYA_CHLAA
Sequence: MLEHLRATDPIIADLIEREAQRQRQGLELIASENYTSLAVMEAQGSVLTNKYAEGLPGRRYYGGCEFVDAIEQLAIERACQLFGTSHANVQPHSGAQANIAVFTALLQPGDTILGMRLDHGGHLTHGSPVNFSGKWYNVHFYGVDAQTGQIDYDDLASKARAIRPKLITSGVSAYPRIIDFARMRQIADEVGALLMADIAHIAGLVAAGEHPSPVGHAHVITTTTHKTLRGPRGGLILMGDDFAKQLNSSVFPGTQGGPLMHVIAGKAVAFGEALRPEFRQYAAQIRRNARALAEGLMAQGLTLVSGGTDNHLMLVDLRSTGLTGAQAQRALDKAAITVNKNAIPDDPQPPMKTSGIRIGTPAVTTRGMREPEMAQIAAWIGEVLMYPDDEARLNRIAGEVADLCRHFPVPADMVQVRG
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NANE_ECOLI
Sequence: MSLLAQLDQKIAANGGLIVSCQPVPDSPLDKPEIVAAMALAAEQAGAVAIRIEGVANLQATRAVVSVPIIGIVKRDLEDSPVRITAYIEDVDALAQAGADIIAIDGTDRPRPVPVETLLARIHHHGLLAMTDCSTPEDGLACQKLGAEIIGTTLSGYTTPETPEEPDLALVKTLSDAGCRVIAEGRYNTPAQAADAMRHGAWAVTVGSAITRLEHICQWYNTAMKKAVL
What is the function of this protein?
Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).
What are the official names of this protein?
Putative N-acetylmannosamine-6-phosphate 2-epimerase, ManNAc-6-P epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanE family.
Protein: RL25_CHLPM
Sequence: METTVLGVQPRIIKKNDAEKIRKSGNVPAVVYHKGEETVAVSVNELELNKLVHTAESHIIDLRFPDGKVKRSFIKAVQFHPVTDRIIHTDFQLFAADEVIEMDVPVSVTGESVGVDKGGKLQILRHNLTLKGKPTDMPDHLVIDITDMEIGSIVHVKDIPAQSYENLEIMIDPETPVVSVVAPKVEVETEEAPEAAAAPEAEA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: SYFB_MESM1
Sequence: MIFSYKHLKKLANLNEISFEDVIKAFNLIGFEVEETKEIRHVENIKYGKVLKIYKNENSDNLTVCEIQFKDKIRIIQTTAKNVEINKYVMAFIPGSKLANNLIESKLLKGIISEGMLVGFDEMLGFEIKLVPKELSKNVIVLDEANLNEDPIANLELHDYLIDLAILPNRSDAISYLVMAKELAAFFGTKIDNDLICLKNLRVSKINSNLEGIFVKSKTLELKLYDKYLLLKSHLKLTNTYKDLENLILIHTGMPIHFLNLKSLEKVNIVSKSSSLEIANRTLKIDNNLVIEKSREIIAIPYLETQKEFEIKDSQKEFFIFMNILSPKEVRKTIKTLKLESSQIKQATKTISHGMQLNAIQYMQSLFEEIEIVNINLNLKPKEILFDHTFINRIAGFEIVKEQKFINAKKSLEILGFKFFEDKILVPAYRHDYTGPYDVIEELFRFYGYDNFPILQPEIKPFKIQKKYDFKFSLASKNYNEIKTYSLVAKEDNNFDPFNFKTEILMKTFPSEKRRIIRNSQAFSLLEIAEYNIKRKLEKINFFDFGMINEGKRALIFASNEKSFNEIKKDLFSLFSYKFELRKTKNNYLHPNASAHIFYENKLIGWMGKINPSLKISDLIFVEILLDEFNISKNQFKEYNFDPLKFRDITFSIEKNQSIDTYLKELKKIKNIFEVQIIDKFEKNEKLNITVRILLEDDAIKNLDEAILKNSWN
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
Protein: RS3_PYRAR
Sequence: MSVQQRRLPVYKKILEENKKKWMIKEFLEYRLSKYGYIDSEILKTPLGTRIVIYAERPSRIIGRKGAIVKEVSNILATKLGVENPQIDVIDVSKIEAPEMFPKVVAYRIANAMAKGVRFRRVMFAAIRQLTEAGAKGFEIVVSGKLSTERARFEKQTFGKLYKIGYDAKNRVRRAVVHVLLKPGIYGIEVRIAPASLQYSDEYKIKPPVRPEAAAQQQQQ
What is the function of this protein?
Binds the lower part of the 30S subunit head.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: KICS2_MOUSE
Sequence: MGESIPLAAPVPVEQAVLETFFSHLGIFSYDKAKDNVEKEREANKSAGGSWLSLLAALAHLAAAEKVYHSLTYLGQKLGGQSFFSRKDSIRTIYTSLHNELKKVVAGRGAPGGTAPHVEELLPHLSEQLCFFVQARMEIADFYEKMYALSTQKFINTEELVSTLDTILRKYSSRFHHPILSPLESSFQLEVGVLSHLLKAQAQISEWKFLPSLVTLHNAHTKLQSWGQTFEKQRETKKHLFGGQSQKAVQPPHLFLWLMKLKTMLLAKFSFYFHEALSRQTTASEMKALTAKANPDLFGKISSFIRKYDAANVSLIFDNRGSESFQGHGYHHPHSYREAPKGVDQYPAVVSLPSDRPVMHWPNVIMIMTDRASDLNSLEKVVHFYDDKVQSTYFLTRPEPHFTIVVIFESKKSERDSHFISFLNELSLALKNPKVFASLKPGSKG
What is the function of this protein?
As part of the KICSTOR complex functions in the amino acid-sensing branch of the TORC1 signaling pathway.  Recruits, in an amino acid-independent manner, the GATOR1 complex to the lysosomal membranes and allows its interaction with GATOR2 and the RAG GTPases.  Functions upstream of the RAG GTPases and is required to negatively regulate mTORC1 signaling in absence of amino acids.  In absence of the KICSTOR complex mTORC1 is constitutively localized to the lysosome and activated.  The KICSTOR complex is also probably involved in the regulation of mTORC1 by glucose.
What are the official names of this protein?
KICSTOR subunit 2.
What is the protein family that this protein belongs to?
Belongs to the KICS2 family.
What are the subcellular locations of this protein?
Lysosome membrane.
Protein: J1L_HCMVA
Sequence: IGEVGSLVRAANCPRPQRNLPYAARTAPAPAQPPSPAPTPSRTPPVSATPRHRRRPERSKTPDKRSAETTQARTVERTGSAPKHRPEARCRQQIPWDDTHRQCAGSVGHNTLTALNTPSRTHHAAPHRRCFGCVGARPGGCVPGVSRACVGCVGGVLAGCVRVCRGRVPGVSCRVCRGRVAGVPAGCGGGVCRRCARPRGVRLRRNECVASRPLFPPRSPGPSSLAPGRCFSCVPRDPCCRPPGTSSFPRGITQTQTRVFFSPCAPHVAFIRRRRPPHHTQLVAVHTRNSKFHPPAKNTPPPLEDPPRG
What are the official names of this protein?
Uncharacterized protein J1L.
Protein: FB247_ARATH
Sequence: MDKKQDQSEENDLFSNIPLELMIEILLKLPAKSIANLIFVSKHWSSIILDKDITELYLTRSSTLPRLLFQVSVSRLKMQFLHSSSLEGPSCDHHRVAVTLNHDLEYRFSPPVRGLICCLNDDIRIIRTEEHQVFTLGAKQEWRMIESRINHKLLSLISFNLRSEEFNVIKFPKDVKHIWSSNLVNYNGKIALTSYSCNGTLDLWVMKDDASKQEWFKDTLSTGELIFAPCFITDPFFFICYDLKEKSARKVVIEGLGDDYVNVSLDHVESPMFLPKVCLSDDD
What are the official names of this protein?
Putative F-box protein At4g29970.
Protein: Y1917_AQUAE
Sequence: MEAQAGFDTFIEATRYLFRGPSPQEILLLIIVLGALITVVSLPFFYSKLKEKQRIRENFFRRARDFDLTEEEASVLWKYVKETVLNPNLVFENKAVFEKVVDRIVQNGNPEEIKLISSIRMKLRFSSLPWFIPLTSTRDIEVYQTGVLVVRNRRVDAYVYDKDEEFLYIALLEPVVVKPGERVSFFFLRENDARYSFDATVEKVFNEGGRTVIVVRHTSEIKRIQLRESVRWKVKLPVKFTLLKENGEEINAEGQLEDISVKGARVCFEGRLDIKEGDRILLDFTLKNYTFKNLLGTVVHQIVYEKRTCLGIKFEELSRKEEEVIGQFILEEQRKLLKAYKEGEV
What are the official names of this protein?
Uncharacterized protein aq_1917.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: TGT_XYLFM
Sequence: MSRLQFQLQATDGAARRGQLSFPCGTVQTPAFMPVGTYGAVKAVLPGQLCDLGAEIILGNTFHLFLRPGLEVIADHGGLHGFMRWNGPILTDSGGFQVFSLAHRRKISEQGVTFAAPTDGAQVFLGPEESMKIQKVLNSDVVMIFDECTPYPATEDVARDSMELSLRWAQRSRDAHDALDNDAALFGIIQGGVHPDLRGRSLDGLQAIGFDGYAIGGLAVGESESERNVILEYLHPRLPVDRPRYLMGVGRPEDLVESVARGVDMFDCVMPTRHARNGQYFTGFGTVKIRNACYARDVDPIEPGCGCPACVGGYTRAYLRHLDRCNEMLASMLGSLHNLWYYETLMANMRAAITAGTFFTFRHSFYLARGLDPPPLPEVASCAG
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: 12AH_CLOS4
Sequence: MIFDGKVAIITGGGKAKSIGYGIAVAYAK
What is the function of this protein?
Catalyzes the oxidation of the 12-alpha-hydroxyl group of bile acids, both in their free and conjugated form.  Also acts on bile alcohols.
What are the official names of this protein?
12-alpha-hydroxysteroid dehydrogenase.
Protein: SYP_THEP3
Sequence: MRLSQLLVPTLREIPAEAEIPSHILMLKAALMRKLASGVYIYLPLGQRVLRKVEQIVREEMDRAGSQEVLMSALIPAELLKESGRWDVFGPEMFKLKDRNERDFCLGPTHEEVFTDLIRNEVKSYRQLPLILYQIQTKFRDERRPRFGVMRSREFIMKDAYSFDMDWEGLDKSFNKMYEAYCRIFDRCGLKYLVVEADSGAMGGKDSKEFMVISGVGEAVIAYCDNCGYAANEEKAECLINQEIVEEMLPKEEVYTPNVRTIEELVNFLGITPNKFVKTLIYKAKDNVVAALVRGDRDLNETKLLNILGIREEELELADASIVEKVTGAKVGFAGPIGLKGEVMIIVDNEIPQMRNFIVGANETDYHIKNVNYGRDFKADVVADIKNVIEGDKCPRCGSPLKIDRGIEVGHIFKLGTKYSDALGAKYVDEEGNEKPIIMGCYGIGINRTVAAIIEQHHDEKGIIWPMSVAPYHVIIVPVNVSNEAQNRVAEDIYAALQKEGIEVLIDDRDLRAGVKFNDADLLGIPIRITVGKKVDDGIVEIKLRENEEAEEVKISDVVEKVKNIIKEKM
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2B_SULIA
Sequence: MSSEKEYVEMLDRLYSKLPEKGRKEGTQALPNLIIFNIGNTTMIRNFAEYCDRIRREDKICMKYLLKELAAPGNVDDKGELIIQGKFSSQVINTLMERFLKAYVECSTCKSLDTVLKKEKKSWYIVCLACGAQTPVKPL
What is the function of this protein?
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
What are the official names of this protein?
Translation initiation factor 2 subunit beta, aIF2-beta, eIF-2-beta.
What is the protein family that this protein belongs to?
Belongs to the eIF-2-beta/eIF-5 family.
Protein: HTPX_RALPJ
Sequence: MFNWIKTFMLMAAITALFIVIGGMIGGRSGMMLALLFALGMNFFSYWFSDKMVLRMYNAQEVNETSAPQFYRMVQELAGRAGLPMPRVYLIDEAQPNAFATGRNPEHAAVAATTGILNILSERELRGVMAHELAHVQHRDILISTISATMAGAISALANFAVFFGGRDSEGRPANPIAGIAVAILAPLAAAMIQMAISRAREFEADRGGATISGDPQALASALDKIHRYAAGIPFAAAEAHPATAQMMIMNPLHGGGLANLFSTHPATEERIARLMQMAQTGQYPA
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL15_MOOTA
Sequence: MRLHELHPAPGSRPRATRVGRGIGSGLGKTSGRGHKGQKARSGGGVRRGFEGGQMPLTRRLPKRGFTNIFARKLVPINVGELERFEPETVVTPELLHDAGLVKQARDGVKILGDGELTKKLTVKVQAASRKAIEKIEAAGGKVEVM
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: PNPH_MOUSE
Sequence: MENEFTYEDYETTAKWLLQHTEYRPQVAVICGSGLGGLTAHLKEAQIFDYNEIPNFPQSTVQGHAGRLVFGLLNGRCCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVETLVVTNAAGGLNPNFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFTAWKQMGEQRKLQEGTYVMLAGPNFETVAESRLLKMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYENLEKANHMEVLDAGKAAAQTLERFVSILMESIPLPDRGS
What is the function of this protein?
Catalyzes the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (PubMed:10859343) (Probable).  Preferentially acts on 6-oxopurine nucleosides including inosine and guanosine (Probable).
What are the official names of this protein?
Purine nucleoside phosphorylase, PNP, Inosine phosphorylase, Inosine-guanosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the PNP/MTAP phosphorylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIF3A_ASPNC
Sequence: MPPPPHIKPENVLKRAQELIAVGQAPAALNVLHEHVTSKRTRSSPIASLEPVMLLFVELCVDLRKGKAAKDGLYQYKNIAQNTNVGTIEVVLKKFIELAEKKVTEAQAKADEIQSSLESAAPSSNVDDLEAIETPETILLATVSGEQSRDRTDRAVVTPWLKFLWETYRTVLEILKNNARLEVMYQTTALQAFQFCLKYTRKTEFRRLCELLRNHVQNAAKYSAQMHAINLSDPDTLQRHLDTRFQQLNVAVELELWQEAFRSIEDIHTLLSLSKRPAKNVMMANYYEKLARIFLVSENYLFHAAAFSRYYNLLRQSAAALAAGQGTKKENPSVTEADMTKAASFVLLSALSIPVISTSRSRGALVDVDEVRKNKNTRLTNLLGMASPPTRAVLFKDALNKGLLKRARPEIRDLYNILEVDFHPLSICKKITPILKQIGADPEMEKYVLPLQQVILTRLFQQLSQVYESVELKFVYELAQFPDPFQITPSMIEKFIMNGCKKGDLAIRVDHISGVLTFDTDVFSSAKALHPGSAAGSAESEVGSVQRLQNTPAEIARLQLTRLAKTLHVTCMYVDPSYNEARLQAKRAALARAEAGAAKEHEETLARRVIIEKKKEAATDALQRKQREEETRKRIRTQQLQEAEKQRLLDEHREREKKRIKDEQDRIRQQELKKQLEELKTGVKGIDISELDLNELDANRLRAMKLAQLEKEKNELNDRIRTTAKRIDHLERAFRREELKHVPEDYEKQKQRDMEIYEATKAEALKEAEDKHKEAVALKHRLSRLVPQFNSFRKEVSEKRHEEFEKRRKAAERDFEAKKMQRIKEVQERRRRERAEREEEERRRKEEEERIRREEEERTAKEEERRRVLAEEKAKREEERKRLDELAAKQKQREEEAEARRAARRTGGAEPEAAPERAAPTERTAPRLNLAPRTGGAGPSWRERQAAKEAAGGTPAAPAAAAPEPAREEPAPVRRTGGYVPPHLRSGASATPAAPAPAPSTERYVPRAMREAGSSQPPSRTQTPGSSSDKPEESKPAAGKWVPRWKQQQGGQ
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit A, eIF3a, Eukaryotic translation initiation factor 3 110 kDa subunit homolog, eIF3 p110, Translation initiation factor eIF3, p110 subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_CUPPJ
Sequence: MASTTVAQLAAELSRSAAALLEQLQAAGLGKATPEDIVTESDKTRLLDYLKRSHGQADDSARKKITLTKRETSEIRQADSTGKTRTVQVEVRKKRVLIKRDEAGADQHNEAADQHALAAEAAEQARREEEERQQAAELARQEAEAKARREAAEREEAERRAKQEALEAEQRRQAELLARKAEEEAAAARAVGEAAEDASRKKAEDEQARVAVERAAAQKAADDAKAAADKARAEQDAARKRREAAEAEARAIQQMLNAPARVLKAPSERKAEEKKAEQTGTLHKPVKPASATATEAKAGDKKPAATTTTTTATTTADKKGKTGKPGSWQDDSSRKKGSGLKTRGDSSGGVGGWRGGPRGRGGRQQHADDGRSNFQAPTEPVVREVHVPETISVADLAHKMAVKASEVIKQMMKLGQMVTINQVLDQETAMIVVEEMGHKAFAAKLDDPEALLVVDGEEHTDAEQLPRPPVVTVMGHVDHGKTSLLDYIRRAKVAAGEAGGITQHIGAYHVETERGVITFLDTPGHEAFTAMRARGAKATDIVILVVAADDGVMPQTKEAIAHAKAAGVPIVVAINKIDKPDANPDRVKQELVAEQVLPEEYGGDSPFVPVSAKTGAGIEDLLEQVLLQAEVLELKAPVDAPAKGLVVEAQLDKGKGPIATILVSSGTLKRGDVVLAGSAYGRVRAMLDENGKPTKEAGPSIPVEIQGLSEVPAAGEEVLVLPDERKAREIALFRQGKFRDVKLAKQQAAKLETMLEQMTEGDVQTLPLIVKADVQGSQEALVQSLQKLSTAEVRVQIVHAGVGAISESDVNLATASKAVIIGFNVRADAGARKLAENHGIDIRYYNIIYDAVDEIKAAMSGMLAPEKRETTIGQVEVRQVFRVPKIGAVAGCMVTDGLVKRNSLVRVLRNNVVVHTGELDSLKRFKDDVKEVKQGFECGLSIKNFNDVQEGDQLEVYEITEVARTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SBNO1_HUMAN
Sequence: MVEPGQDLLLAALSESGISPNDLFDIDGGDAGLATPMPTPSVQQSVPLSALELGLETEAAVPVKQEPETVPTPALLNVRQQPPSTTTFVLNQINHLPPLGSTIVMTKTPPVTTNRQTITLTKFIQTTASTRPSVSAPTVRNAMTSAPSKDQVQLKDLLKNNSLNELMKLKPPANIAQPVATAATDVSNGTVKKESSNKEGARMWINDMKMRSFSPTMKVPVVKEDDEPEEEDEEEMGHAETYAEYMPIKLKIGLRHPDAVVETSSLSSVTPPDVWYKTSISEETIDNGWLSALQLEAITYAAQQHETFLPNGDRAGFLIGDGAGVGKGRTIAGIIYENYLLSRKRALWFSVSNDLKYDAERDLRDIGAKNILVHSLNKFKYGKISSKHNGSVKKGVIFATYSSLIGESQSGGKYKTRLKQLLHWCGDDFDGVIVFDECHKAKNLCPVGSSKPTKTGLAVLELQNKLPKARVVYASATGASEPRNMAYMNRLGIWGEGTPFREFSDFIQAVERRGVGAMEIVAMDMKLRGMYIARQLSFTGVTFKIEEVLLSQSYVKMYNKAVKLWVIARERFQQAADLIDAEQRMKKSMWGQFWSAHQRFFKYLCIASKVKRVVQLAREEIKNGKCVVIGLQSTGEARTLEALEEGGGELNDFVSTAKGVLQSLIEKHFPAPDRKKLYSLLGIDLTAPSNNSSPRDSPCKENKIKKRKGEEITREAKKARKVGGLTGSSSDDSGSESDASDNEESDYESSKNMSSGDDDDFNPFLDESNEDDENDPWLIRKDHKKNKEKKKKKSIDPDSIQSALLASGLGSKRPSFSSTPVISPAPNSTPANSNTNSNSSLITSQDAVERAQQMKKDLLDKLEKLAEDLPPNTLDELIDELGGPENVAEMTGRKGRVVSNDDGSISYESRSELDVPVEILNITEKQRFMDGDKNIAIISEAASSGISLQADRRAKNQRRRVHMTLELPWSADRAIQQFGRTHRSNQVTAPEYVFLISELAGEQRFASIVAKRLESLGALTHGDRRATESRDLSRFNFDNKYGRNALEIVMKSIVNLDSPMVSPPPDYPGEFFKDVRQGLIGVGLINVEDRSGILTLDKDYNNIGKFLNRILGMEVHQQNALFQYFADTLTAVVQNAKKNGRYDMGILDLGSGDEKVRKSDVKKFLTPGYSTSGHVELYTISVERGMSWEEATKIWAELTGPDDGFYLSLQIRNNKKTAILVKEVNPKKKLFLVYRPNTGKQLKLEIYADLKKKYKKVVSDDALMHWLDQYNSSADTCTHAYWRGNCKKASLGLVCEIGLRCRTYYVLCGSVLSVWTKVEGVLASVSGTNVKMQIVRLRTEDGQRIVGLIIPANCVSPLVNLLSTSDQSQQLAVQQKQLWQQHHPQSITNLSNA
What are the official names of this protein?
Protein strawberry notch homolog 1, Monocyte protein 3, MOP-3.
What is the protein family that this protein belongs to?
Belongs to the SBNO family.
Protein: CP91_CONRE
Sequence: MHLSLARSAVLILLLLFALGNFVGVQPGQITRDADHGINLRSLRKQMSRSPLVKGAFCGQACSSVKCPKKCFCHPEEKVCYREMRTKERD
What is the function of this protein?
Probable neurotoxin that inhibits ion channels.
What are the official names of this protein?
Conotoxin Rg9.1.
What is the protein family that this protein belongs to?
Belongs to the conotoxin P superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MATK_APOAN
Sequence: MEEIQRYLQLDRSQQPSFLYPLIFQEYIYALAHGHNLNRAILLENPGYDNKSSFLIVKRLITRMYQQNHFLTSANDSSQNPFIGRNKNLYSKMISEGFSFIVEIPFSMRLISSEERKGIFQSHNLRSIHSIFPFLEDNFSHFNLMLDIQIPHPVHLEILVQTLRYWVKDAPSLHLLRFFLREYCNCNKIISTKKPGFLFLTKKNQRLFFLLYNFYVCEYESIFVFLHTQSSHLRPTSFGVFRERIYFYGKIEHFAEVFAKDFPTNLCLFKYPFMHYVRYQGKSILLSRGTALLMNKWKSYLVNFWQCNFDLWVHSRRAYIKQVYNYSLDFMGYLSIVRQTPLTVRSQMLKNAFLIKNPINKLDTLVPIIPLIGSFAKAKFCNLLGHPISKPVRTDLSDSDIMDRFGRICRNLSHYYSGSSKKKSLYRIKYILRLSCAKTLARKHKSTVRAFLKRLGSEFLEEFFMSEEEVFSLTFPRVYSLFLGVYRSRIWYLDITCINDLANQQ
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RIMK_HAEIG
Sequence: MKLLMLCREPRLYSCQRLKEAAKHQGHEMDILDPNHCFLKLSQNPPHFQIFYQENSESKPYLLPDYDAVLPRFGTTSTQMGCSVLQHFEGKGTFCLNSSQAFLNARDKWKSLQLLLKAGVPVPNSLFSGGEVQAHATIPHISSPTILKTLNGSQGIGVILAEKPQSAVSIMEAFKQTNISMLQQDFIEEAGNADIRCFVMGDQVVATMQRIGQNGEFRANCHRGGKTEKITLSDEEKQIAIQATKAIGLDVAGVDLIRSKNGLLVLEVNASPGLEMIEKTSGIDIAAEIIDYIEINAFINSR
What are the official names of this protein?
Probable alpha-L-glutamate ligase.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: RS5_SYNS9
Sequence: MTDSSPQSNPNAVPGAADVPAAAQGQQQEQRRGGGGGGRGDRRGDRRGGRRGQDRDSEWQERVVQIRRVSKTVKGGKKMSFRAIVVVGNEKGQVGVGVGKAGDVIGAVRKGVADGKKHLVKVPLTRHSSIPTLSNGRDGAASVLIRPAAPGTGVIAGGSIRTVLELAGIKNVLAKRLGSKTPLNNARAAMVALSSLRTHKETAKERGISLEQIYS
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.