PharMolix/UniProtQA huggingface dataset:
Protein: HLH30_CAEEL
Sequence: MIRQLNSPGGGGGLGLNNPRAQQPPGAQQQQQPQQAQQQFYDDEPYQANASQFRFGAGKSMEQRRETGNLIPIAQRSMGSTSTPFGSAPTQSYFGGGSSGAALSSPRKMQQTHQMLFGNIQPPRGSPPSDGSDKIHRFGESPTPGGVGGVFGTELDDLIIDELMGMEDDQRMRPGATRPMTIGGEKTMSMARPIPGASSRAGSGHSGSPITIPNAMSNNFRQVVSSSAPTSSIDIEKMIGAVSNGGGNSGGDNDPEDYYRDRRKKDIHNMIERRRRYNINDRIKELGQMLPKNTSEDMKLNKGTILKASCDYIRVLQKDREQAMKTQQQQKSLESTAHKYADRVKELEEMLARQGVQVPPSHLPPIPKVIERPIKQEIDESPPNHTPTGSFVSSSGFLSEVTNNTAAMQITSPNDSRPNNFMNNSAPSDSFFSVGSASPPDYRTSSGTASWKLPGSNAFSDLMMDDLNPMMNGDPLISSAGAHPSPHFHSSQMSPDIHWDASGFSPDPINTQQSNSGHYHMDFS
What is the function of this protein?
Transcription factor which regulates the expression of genes involved in lipid metabolism and autophagy in response to nutrient availability, bacterial pore-forming toxins or heat shock (PubMed:23604316, PubMed:23925298, PubMed:27001890, PubMed:27875098, PubMed:28198373).  Binds to the E-box motif 5'-CACGTG-3' (PubMed:19632181).  Under fasting conditions, binds to the promoter and activates the expression of lipase genes lipl-2, lipl-3 and lipl-5, and to a lesser extent, lipl-1, thereby regulating lipolysis (PubMed:23604316).  Involved in modulating longevity in response to TOR signaling, dietary restriction, germline signaling, heat shock and the insulin-like signaling pathway (PubMed:23925298, PubMed:27001890, PubMed:24882217, PubMed:28198373).  Involved in the immune response to infection by the S. aureus bacterium, probably acting downstream of the protein kinase dkf-1, leading to the transcriptional activation of host defense genes (PubMed:24882217, PubMed:27184844).  May also play a role in lysosomal biogenesis in response to nutrient availability (PubMed:23604316).
What are the official names of this protein?
Helix-loop-helix protein 30.
What is the protein family that this protein belongs to?
Belongs to the MiT/TFE family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Localization to nucleus enhanced during fasting and on mutant backgrounds involved in modulating longevity: glp-1, let-363 (tor), eat-2, daf-2, clk-1 or rsks-1 (PubMed:23604316, PubMed:23925298). Nuclear localization abolished on mml-1;glp-1 or mxl-2;glp-1 mutant backgrounds (PubMed:27001890). Localization to nucleus enhanced as a result of bacterial pore-forming toxin treatment, or heat shock (PubMed:27875098, PubMed:28198373). SUBCELLULAR LOCATION: Nucleus. Note=(Microbial infection) Localization to nucleus enriched rapidly after Staphylococcus aureus infection.
Protein: CCL4_RAT
Sequence: MKLCVSAFSLLLLVAAFCDSVLSAPIGSDPPTSCCFSYTSRKIHRNFVMDYYETSSLCSQPAVVFLTKKGRQICADPSEPWVNEYVNDLELN
What is the function of this protein?
Monokine with inflammatory and chemokinetic properties.
What are the official names of this protein?
C-C motif chemokine 4, Macrophage inflammatory protein 1-beta, MIP-1-beta, Small-inducible cytokine A4.
What is the protein family that this protein belongs to?
Belongs to the intercrine beta (chemokine CC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL13_MARMM
Sequence: MKTISVKPADVEKKWVVIDAEGAVVGRLAAYVATRLRGKHRPDYTPHVDMGDNIIIVNADKVVFTGKKRDDKRYYHHTGHPGGIKETSPAKILDGRFPERVVEKAVLRMLPKDSPLARQQYSNLRVYAGPDHKHEAQQPEVVDFKSMNSKNTRG
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: LETM1_CHICK
Sequence: MLLQSCGRRACRLPRALRRQAPLGNLGDRACLSCTSLRLANKMTVHFKYCTSVAPVYAYSKKDHYCCWTKGLERTYFTLMSSSGSWTPLAAMGVLGPKYLPVRWWHSSRSLQDDSIVEKSLKSLKDKNKKLEEGGPVYSPTEVEVVKKSIGQRIVDELKHYYHGFRLLWIDTKIAARMLWRILHGNTLSRRERRQFLRICADLFRLVPFLVFLVVPFMEFLLPVALKLFPNMLPSTFETKSKKEERLKKQLRVKLELAKFLQDTIEEMALKNKAAKGNVTKDFSTFFQKIRETGERPSNEEILRFSKLFEDELTLDNLTRPQLVALCKLLELQSIGTNNFLRFQLTMRLRTIKADDKMIAEEGVDSLTVKELQAACRARGMRALGVTEERLREQLKQWLDLHLNQEIPTSLLILSRAMYLPDTLSPADQLKTTLQTLPESVAKEAQVKVAEVEGEKVDNKARLEATLQEEAAIRKENEEKEMERITEAAEKAKETLQVAAMKLESAVDLEPAVLQVKESQVAMDSKQELAKADMETLKDTAPVLEGIKGEEITKEEIDMLSDACNKLQEQKKSLTKEKEELEELKGDIQEYNEDLQEIKELSKAGQEEVVEESKASKRLTKRVNRMIGQIDKIINELETNQKTVDVKLDRGDSPPAGENLISIAELINAMKQIQKIPEEKLTRIAEALDENKDGKIDIDNVVKVVELIDKEDVDIGTSQVAEIMALLQKEEKLEEKEKAKEKQDKEAAEVKN
What is the function of this protein?
Plays an important role in maintenance of mitochondrial morphology and in mediating either calcium or potassium/proton antiport (By similarity).  Mediates proton-dependent calcium efflux from mitochondrion (By similarity).  Functions also as an electroneutral mitochondrial proton/potassium exchanger (By similarity).  Required for the maintenance of the tubular shape and cristae organization (By similarity).
What are the official names of this protein?
Mitochondrial proton/calcium exchanger protein, Electroneutral mitochondrial K(+)/H(+)exchanger, KHE, Leucine zipper-EF-hand-containing transmembrane protein 1.
What is the protein family that this protein belongs to?
Belongs to the LETM1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: CTSR_STAAN
Sequence: MHNMSDIIEQYIKRLFEESNEDVVEIQRANIAQRFDCVPSQLNYVIKTRFTNEHGYEIESKRGGGGYIRITKIENKDATGYINHLLQLIGPSISQQQAYYIIDGLLDKMLINEREAKMIQAVIDRETLSMDMVSRDIIRANILKRLLPVINYY
What is the function of this protein?
Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region.
What are the official names of this protein?
Transcriptional regulator CtsR.
What is the protein family that this protein belongs to?
Belongs to the CtsR family.
Protein: KLHL9_HUMAN
Sequence: MKVSLGNGEMGVSAHLQPCKAGTTRFFTSNTHSSVVLQGFDQLRIEGLLCDVTLVPGDGDEIFPVHRAMMASASDYFKAMFTGGMKEQDLMCIKLHGVNKVGLKKIIDFIYTAKLSLNMDNLQDTLEAASFLQILPVLDFCKVFLISGVSLDNCVEVGRIANTYNLIEVDKYVNNFILKNFPALLSTGEFLKLPFERLAFVLSSNSLKHCTELELFKAACRWLRLEDPRMDYAAKLMKNIRFPLMTPQDLINYVQTVDFMRTDNTCVNLLLEASNYQMMPYMQPVMQSDRTAIRSDSTHLVTLGGVLRQQLVVSKELRMYDERAQEWRSLAPMDAPRYQHGIAVIGNFLYVVGGQSNYDTKGKTAVDTVFRFDPRYNKWMQVASLNEKRTFFHLSALKGHLYAVGGRSAAGELATVECYNPRMNEWSYVAKMSEPHYGHAGTVYGGLMYISGGITHDTFQNELMCFDPDTDKWMQKAPMTTVRGLHCMCTVGDKLYVIGGNHFRGTSDYDDVLSCEYYSPTLDQWTPIAAMLRGQSDVGVAVFENKIYVVGGYSWNNRCMVEIVQKYDPEKDEWHKVFDLPESLGGIRACTLTVFPPEENPGSPSRESPLSAPSDHS
What is the function of this protein?
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis.  The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis.
What are the official names of this protein?
Kelch-like protein 9.
Protein: NANM_BRUA2
Sequence: MFSLIRAKRLAIGIAALAWSTGAVMASEHWPDLPVGIKNGAAARIGNMAYVGLGSAGTDFYALDLNNPSKGWVKRANFIGPATNGAAMAAAGGKIFAFSGNGKATPDAKSPIIFDTAYVYDPGSDGWSKLDTQTPVGLSGAKAVGLADGRIAIFGGYNKELFDKYLADVGAIDKDKEPEAYRNLVDSYMGMKPEAYRWNDEVLVYDPAGNNWGSLGANPFLPNCDPAMATMGEGDFLLVSGEIKPGLRTPEAKLVKIRDGAAHWQKVSDLPPLSGSEPQEGVAGAYAGKAGDDVLVAGGANFKGAQANAAAGKWFAHDGLAKSWRDDVYAFDGKDWKVAGKLPRGLAYGAAFDAPGGLLVVGGEDRDGKARKEVFLLKWDGKALSVEN
What is the function of this protein?
Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers.  Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer.  In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses.
What are the official names of this protein?
N-acetylneuraminate epimerase, N-acetylneuraminate mutarotase, Neu5Ac mutarotase, Sialic acid epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanM family.
What are the subcellular locations of this protein?
Periplasm.
Protein: ATNG_RAT
Sequence: MTELSANHGGSAKGTENPFEYDYETVRKGGLIFAGLAFVVGLLILLSKRFRCGGSKKHRQVNEDEL
What is the function of this protein?
May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase.
What are the official names of this protein?
Sodium/potassium-transporting ATPase subunit gamma, Na(+)/K(+) ATPase subunit gamma, FXYD domain-containing ion transport regulator 2, Sodium pump gamma chain.
What is the protein family that this protein belongs to?
Belongs to the FXYD family.
What are the subcellular locations of this protein?
Membrane; Single-pass type III membrane protein.
Protein: X191_ECOLX
Sequence: MKKWMLAICLMFINGICEAADCFDLAGRDYKIDPDLLRAISWKESRYRVNAIGINPVTGYGSGLMQVDSQHFNELARYGIKPEHLTTDPCMNIYTGAYYLAIAFKKWGVSWEAVGAYNAGFRKTERQNQRRLAYASEVYRIYTWIKSSKGIRVPTTKKSLSQINSVQKN
What are the official names of this protein?
X polypeptide, ORF 19, ORF169, P19 protein.
What is the protein family that this protein belongs to?
Belongs to the IagB/IpgF/P19 family.
Protein: CP110_HUMAN
Sequence: MEEYEKFCEKSLARIQEASLSTESFLPAQSESISLIRFHGVAILSPLLNIEKRKEMQQEKQKALDVEARKQVNRKKALLTRVQEILDNVQVRKAPNASDFDQWEMETVYSNSEVRNLNVPATFPNSFPSHTEHSTAAKLDKIAGILPLDNEDQCKTDGIDLARDSEGFNSPKQCDSSNISHVENEAFPKTSSATPQETLISDGPFSVNEQQDLPLLAEVIPDPYVMSLQNLMKKSKEYIEREQSRRSLRGSINRIVNESHLDKEHDAVEVADCVKEKGQLTGKHCVSVIPDKPSLNKSNVLLQGASTQASSMSMPVLASFSKVDIPIRTGHPTVLESNSDFKVIPTFVTENNVIKSLTGSYAKLPSPEPSMSPKMHRRRSRTSSACHILINNPINACELSPKGKEQAMDLIIQDTDENTNVPEIMPKLPTDLAGVCSSKVYVGKNTSEVKEDVVLGKSNQVCQSSGNHLENKVTHGLVTVEGQLTSDERGAHIMNSTCAAMPKLHEPYASSQCIASPNFGTVSGLKPASMLEKNCSLQTELNKSYDVKNPSPLLMQNQNTRQQMDTPMVSCGNEQFLDNSFEKVKRRLDLDIDGLQKENCPYVITSGITEQERQHLPEKRYPKGSGFVNKNKMLGTSSKESEELLKSKMLAFEEMRKRLEEQHAQQLSLLIAEQEREQERLQKEIEEQEKMLKEKKAMTAEASELDINNAVELEWRKISDSSLLETMLSQADSLHTSNSNSSGFTNSAMQYSFVSANEAPFYLWGSSTSGLTKLSVTRPFGRAKTRWSQVFSLEIQAKFNKITAVAKGFLTRRLMQTDKLKQLRQTVKDTMEFIRSFQSEAPLKRGIVSAQDASLQERVLAQLRAALYGIHDIFFVMDAAERMSILHHDREVRKEKMLRQMDKMKSPRVALSAATQKSLDRKKYMKAAEMGMPNKKFLVKQNPSETRVLQPNQGQNAPVHRLLSRQGTPKTSVKGVVQNRQKPSQSRVPNRVPVSGVYAGKIQRKRPNVATI
What is the function of this protein?
Necessary for centrosome duplication at different stages of procentriole formation.  Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation (PubMed:17719545, PubMed:17681131, PubMed:23486064, PubMed:30375385, PubMed:35301795).  Also involved in promoting ciliogenesis.  May play a role in the assembly of the mother centriole subdistal appendages (SDA) thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation (By similarity).  Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2 (PubMed:16760425).
What are the official names of this protein?
Centriolar coiled-coil protein of 110 kDa, Centrosomal protein of 110 kDa, CP110, Cep110.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium basal body. Note=Recruited early and then associates with the growing distal tips. Recruited to the mother centriole by KIF24 (PubMed:21620453). Removed from centrioles by TTBK2, leading to initiation of ciliogenesis and localizes only to the daughter centriole in ciliated cells. In cytotoxic T lymphocytes remains associated with the mother centriole during docking of the centrosome at the immunological synapse upon target contact (By similarity). Recruited at the distal end of the mother centriole by MPHOSPH9 (PubMed:30375385).
Protein: PYRB_SACS2
Sequence: MRLRHVVSSLDLTRDDYFRIFELADKFYDVKKLNYLSGKVVSLAFFEPSTRTAQSFHTAAIKLGADVIGFASEESTSIAKGENLADTIRMLNNYSNCIVMRHKFDGAALFASEISDIPIINAGDGKHEHPTQAVIDLYTVYKAFGEIDGRTFALLGDLKYARTVNSLLRALTRFKPKKVFLISPSQLKVRREILDELNYPVIETENPYDVIQEIDVLYVTRIQKERFVDEVEYEKVKESYVVDLKLVNMMKKDGIILHPLPRVTEIDRRVDKTVNAKYFYQASLAVPVRMALFYEVLGDREDD
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: GLGB_SYNP6
Sequence: MTGTTPLPSSSLSVEQVNRIASNQEQNPFDILGPHPYEHEGQAGWVIRAYLPEAQEAAVICPALRREFAMHPVHHPHFFETWVPEETLEIYQLRITEGERERIIYDPYAFRSPLLTDYDIHLFAEGNHHRIYEKLGAHPCELENVAGVNFAVWAPSARNVSILGDFNSWDGRKHQMARRSNGIWELFIPELTVGAAYKYEIKNYDGHIYEKSDPYGFQQEVRPKTASIVADLDRYTWGDADWLERRRHQEPLRQPISVYEVHLGSWMHASSDAIATDAQGKPLPPVPVADLKPGARFLTYRELADRLIPYVLDLGYSHIELLPIAEHPFDGSWGYQVTGYYAATSRYGSPEDFMYFVDRCHQNGIGVILDWVPGHFPKDGHGLAFFDGTHLYEHADSRQGEHREWGTLVFNYGRHEVRNFLAANALFWFDKYHIDGIRVDAVASMLYLDYNRKEGEWIPNEYGGRENIEAADFLRQVNHLIFSYFPGALSIAEESTSWPMVSWPTYVGGLGFNLKWNMGWMHDMLDYFSMDPWFRQFHQNNVTFSIWYAFSENFMLALSHDEVVHGKSNLIGKMPGDEWQKFANLRCLLGYMFTHPGKKTLFMGMEFGQWAEWNVWGDLEWHLLQYEPHQGLKQFVKDLNHLYRNAPALYSEDCNQAGFEWIDCSDNRHSIVSFIRRAHESDRFLVVVCNFTPQPHAHYRIGVPVAGFYREIFNSDARSYGGSNMGNLGGKWTDEWSCHNRPYSLDLCLPPLTTLVLELASGPESLSEAANSPL
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: Y65_BPT3
Sequence: MLQPINHVLTHPDDIPSMPRAAKEYLQVRFNQAYVMESGEYRALRAAGYSESFIAGVMHGLYLASRTLDEIEVRKEQLRQE
What are the official names of this protein?
Uncharacterized gene 6.5 protein.
Protein: ODPB3_ARATH
Sequence: MSAILQGAGAATALSPFNSIDSNKLVAPSRSSLSVRSKRYIVAGSDSKSFGSSLVARRSEPLIPNAVTTKADTAASSTSSKPGHELLLFEALQEGLEEEMDRDPHVCVMGEDVGHYGGSYKVTKGLADKFGDLRVLDTPICENAFTGMGIGAAMTGLRPVIEGMNMGFLLLAFNQISNNCGMLHYTSGGQFTIPVVIRGPGGVGRQLGAEHSQRLESYFQSIPGIQMVACSTPYNAKGLMKAAIRSENPVILFEHVLLYNLKESIPDEEYICNLEEAEMVRPGEHITILTYSRMRYHVMQAAKTLVNKGYDPEVIDIRSLKPFDLYTIGNSVKKTHRVLIVEECMRTGGIGASLTAAINENFHDYLDAPVMCLSSQDVPTPYAGTLEEWTVVQPAQIVTAVEQLCQ
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
What are the official names of this protein?
Pyruvate dehydrogenase E1 component subunit beta-3, chloroplastic.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LEPA_SHISS
Sequence: MKNIRNFSIIAHIDHGKSTLSDRIIQICGGLSDREMEAQVLDSMDLERERGITIKAQSVTLDYKASDGETYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAGQGVEAQTLANCYTAMEMDLEVVPVLNKIDLPAADPERVAEEIEDIVGIDATDAVRCSAKTGVGVQDVLERLVRDIPPPEGDPEGSLQALIIDSWFDNYLGVVSLIRIKNGTLRKGDKVKVMSTGQTYNADRLGIFTPKQVDRTELKCGEVGWLVCAIKDIHGAPVGDTLTLARNPAEKALPGFKKVKPQVYAGLFPVSSDDYEAFRDALGKLSLNDASLFYEPESSSALGFGFRCGFLGLLHMEIIQERLEREYDLDLITTAPTVVYEVETTSREVIYVDSPSKLPAVNNIYELREPIAECHMLLPQAYLGNVITLCVEKRGVQTNMVYHGNQVALTYEIPMAEVVLDFFDRLKSTSRGYASLDYNFKRFQASDMVRVDVLINGERVDALALITHRDNSQNRGRELVEKMKDLIPRQQFDIAIQAAIGTHIIARSTVKQLRKNVLAKCYGGDISRKKKLLQKQKEGKKRMKQIGNVELPQEAFLAILHVGKDNK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y2312_GRAFK
Sequence: MKITFYGQNTLALKIGDIHVLVDPFITGNDLSKDKVDINDLKADYILLTHAHQDHILDAEAIAKNTGAVIVSNFEIANHYEEKGFEVHPMNHGGSWDFEFGKVKYVNAIHTSSFPDGSYGGQPGGFVIEGEHKNIYIAGDTALTMDMKLIPMHTKLDIAVLPIGDNFTMGINDAIIASDFIECDKIIGCHYDTFGYIEIDHEEAKKKFYEKGKDLMLLDIGESIEL
What are the official names of this protein?
UPF0173 metal-dependent hydrolase GFO_2312.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: WAK2_ARATH
Sequence: MKVQEGLFVVAVFYLAYTQLVKGQPRKECQTRCGNVAVEYPFGTSPGCYYPGDESFNLTCNEQEKLFFGNMPVINMSLSGQLRVRLVRSRVCYDSQGKQTDYIAQRTTLGNFTLSELNRFTVVGCNSYAFLRTSGVEKYSTGCISICDSATTKNGSCSGEGCCQIPVPRGYSFVRVKPHSFHNHPTVHLFNPCTYAFLVEDGMFDFHALEDLNNLRNVTTFPVVLDWSIGDKTCKQVEYRGVCGGNSTCFDSTGGTGYNCKCLEGFEGNPYLPNGCQDINECISSRHNCSEHSTCENTKGSFNCNCPSGYRKDSLNSCTRKVRPEYFRWTQIFLGTTIGFSVIMLGISCLQQKIKHRKNTELRQKFFEQNGGGMLIQRVSGAGPSNVDVKIFTEKGMKEATNGYHESRILGQGGQGTVYKGILPDNSIVAIKKARLGNRSQVEQFINEVLVLSQINHRNVVKVLGCCLETEVPLLVYEFINSGTLFDHLHGSLYDSSLTWEHRLRIATEVAGSLAYLHSSASIPIIHRDIKTANILLDKNLTAKVADFGASRLIPMDKEQLTTIVQGTLGYLDPEYYNTGLLNEKSDVYSFGVVLMELLSGQKALCFERPHCPKNLVSCFASATKNNRFHEIIDGQVMNEDNQREIQEAARIAAECTRLMGEERPRMKEVAAELEALRVKTTKYKWSDQYRETGEIEHLLGVQILSAQGETSSSIGYDSIRNVTTLDIEAGR
What is the function of this protein?
Serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component.  Binding to pectin may have significance in the control of cell expansion, morphogenesis and development.
What are the official names of this protein?
Wall-associated receptor kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: CLS_LISW6
Sequence: MGLLAYLLVVLLILNVFFAAVTVFLERRDTSATWAWLLVLTFVPIFGFIIYLIFGRKLSGKKIFDWKGQEKIGIQESTANQIEMIRQKEFPFSDSNVKKHRDLIYLLLVNDGAILTQDNEVELFIDGHEKFDALIADIEKAKDHIHLIYYIFHSDELGNRLMRVLERKAAEGLNVKIIYDAMGSRTTKKSFFRTFEKNGGLVRPFFPSKLPLINFRLNYRNHRKLAIIDGDISYIGGFNIGDEYLGLSKKFGYWRDTHLRVHGKAVYAMQTRFIMDWNSASSTNKIDYKPRYFPTFHGKGHTSMQIVSSGPDSEWQQIKNGYIKMINAAKKTIYLQSPYFIPDASLLEAIKIAALSGVDVRVMIPNKPDHAFVYRATTNYAGELMETGAKIFIYDNGFIHAKTLVVDGEIASVGTANMDFRSFRLNFEVNAFIYEKKMVQKLEDAFLEDILKSYQLTPELYAKRSLWIKFKEAVSRLLSPIL
What is the function of this protein?
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
What are the official names of this protein?
Cardiolipin synthase, CL synthase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KDGD_ACIB3
Sequence: MDALELKNIISDGLLSFPVTDFDQNGDFNKSSYAKRLEWLAPYGASALFAAGGTGEFFSLTGNEYSEVIKTAVDTCRGSVPIIAGAGGPTRQAIEQAKEAERLGAHGILLMPHYLTEASQEGLIEHVKQVCNSVDFGVIFYNRSVSRLNLDSIQKLTEMCPNLIGFKDSSGQIDMMTAVTQTMGDRLSYLGGLPTAEVFAAPYKALGCPVYSSAVFNFIPKTAMEFYNALRSDDFETTNRLIKDFFLPLIKIRDRKSGYAVSMIKAGAKIVGHDAGPVRPPLSDLTQADYEDLAALIATLGPQ
What are the official names of this protein?
Probable 5-dehydro-4-deoxyglucarate dehydratase, 5-keto-4-deoxy-glucarate dehydratase, KDGDH.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
Protein: EFG1_POLSJ
Sequence: MSRATPIQNYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAATTCFWKGMDTSLPEHRINIIDTPGHVDFTIEVERSMRVLDGACMVYCAVGGVQPQSETVWRQANKYKVPRLAFVNKMDRTGANFFKVVEQMKLRLKASPVPMVIPIGAEENFTGVVDLLKMKAIIWDEASQGMKFTYSEIPAELVELAKEWREKMVEAAAESSEELMNKYLEEGDLTEAEIKLGIRTRTIASEIQPMYCGSAFKNKGVQRMLDAVIEFMPSPIDIPPVKGMDEDEAPVTRKADDEEKFSALAFKLMTDPFVGQLTFVRVYSGVLKKGDSVYNPIKGKKERIGRIVQMHANNREEVSEIRAGDIAACVGLKDVTTGETLCDPDAIVMLERMVFPEPVITQAVEPKTKADQEKMGIALQRLAQEDPSFRVKTDEESGQTLIAGMGELHLEIIVDRMKREFGVEANVGKPQVAYRETIRKTVEDAEGKFVRQSGGKGQYGHVVLKIEPNEAGKGIEFVDAIKGGVVPREYIPAVEKGINEAVTSGVLAGYPVVDVKVTLHFGSYHDVDSNELAFKMAAIFGFKEGCRKASPVILEPMMAVEVETPEDYAGNVMGDLSSRRGMVQGMEDMVGGGKAIKAEVPLSEMFGYSTTLRSMSQGRATYSMEFKHYSEAPRNVSEAIMASRAK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G 1, EF-G 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYOE_VIBVU
Sequence: MSKTLSVDKSQLRSPWSTYWTLTKPKVVALMLLTSVVGMSLAPHEHFTWHQALIALVGIALMAGSAAAFNHLIDRRIDAKMARTYRRPLPKGDVSPFNVLLFALLIGSLGFLSLMLWVNSLTAYLTFASLLGYAAVYTLYLKRATPQNIVIAGIAGAMPPLLGWTSITGELHPHAWVLVMIIFIWTPPHFWALAIHRKEDYAKVNIPMLPVTHGVEYTKTSILLYAILLALVCMLPVLVGMASYLYLFSALVLNVCFVRYAIKLKFRAEERTAIEMFRFSIYFLLLLFCALLLDQQLAL
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRAP1_BOVIN
Sequence: MARELRMLLLWGRRLRAPALAAACGGKPVLCPWRPPAQSWGPPRSLASSFHVGRPFSSQAAEDQAEAGPLHSVISSLEAVQGSATKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSEGQALPDMEIHLQTDADRGTITIQDTGVGMSREELVSNLGTIARSGSKAFLDALQNQAEAGSKIIGQFGVGFYSAFMVADRVEVYSRSVDAGSLGYRWLSDGSGVFEVAEASGVRTGTKIIIHLKADSREFASEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVGEGQHEEFYRYVAQAHDRPRYTLHYRTDAPLSIRSIFYVPDAKPSMFDVSRELGSSVSLYSRKVLIQTKATNILPTWLRFVRGVVDSEDIPLNLSRELLQESALIRKLQGVLQQRLIKFFTDQSKKDAEKYARFFEDYGLFVREGIVTTAEQEVKEDIAKLLRYESSALPAGQLTSLSDYASRMQAGTRNIYYLCAPNRHLAEHSPYYEAMKRKNTEVLFCYEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDGAPAGDCLSEKETEDLMAWMRNALGSRITDVKVTLRLDTHPAMITVLEMGAARHFLRMRQLAKTQEERAQLLQPTLEINPRHVLIKKLSQLRDSEPDLAQLLVDQIYENAMITAGLIDDPRPMVGRLNQLLVKALERH
What is the function of this protein?
Chaperone that expresses an ATPase activity.  Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I.  Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis.  The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.
What are the official names of this protein?
Heat shock protein 75 kDa, mitochondrial, HSP 75, TNFR-associated protein 1, Tumor necrosis factor type 1 receptor-associated protein, TRAP-1.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane. Mitochondrion matrix.
Protein: Y3692_BRUSI
Sequence: MAGHSQFKNIMHRKGRQDAVRSKMFSKLAREITVAAKQGLPDPAMNPRLRLAIQNAKAQSMPKDNIERAIKKAAGNDGENYDEVRYEGRGPGGVSVIVEALTDNRNRTASNVRAAFTKSGGSLGETGSVSFMFDRVGEIVYKPEAGDADKVMEAAIEAGAEDVQSGEDGHVILCAFEDIGEVSKALEAALGEAESIKTIWKPQTNTELDEEKARSVLKLLSVLEDDDDVQNVYTNFEVSDEVMEKLSA
What are the official names of this protein?
Probable transcriptional regulatory protein BSUIS_B1192.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.