PharMolix/UniProtQA huggingface dataset:
Protein: PSME3_PIG
Sequence: MASLLKVDQEVKLKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPILNIHDLTQIHSDMNLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIEKVKPEIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVESEAASYLDQISRYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYVTLHDMILKNIEKIKRPRSSNAETLY
What is the function of this protein?
Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome.  11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits.  Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage.  May also be involved in cell cycle regulation.  Mediates CCAR2 and CHEK2-dependent SIRT1 inhibition (By similarity).
What are the official names of this protein?
Proteasome activator complex subunit 3, Activator of multicatalytic protease subunit 3, Proteasome activator 28 subunit gamma, PA28g, PA28gamma.
What is the protein family that this protein belongs to?
Belongs to the PA28 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Localizes to the cytoplasm during mitosis following nuclear envelope breakdown at this distinct stage of the cell cycle which allows its interaction with MAP3K3 kinase.
Protein: RPOC2_DIOEL
Sequence: MGVFMTERADLVFHNKVIDGTAMKRLISRLIDHFGMGYTSHILDQSKILGFQQATATSISLGIDDLLTIPSKEWLVQDTEQQRFILEKHYHYANVHAVEKLRQSIEIWYATSEYLRQEMNPNFRMTDPSNPVHLMSFSGARGNASQVHQLVGMRGLMSDPQGQMIDLPIQSNLREGLSLTEYIISCYGARKGVVDTAVRTSDAGYLTRRLVEVVQHIIVRRTDCGTIRSISVSPRKGMTEKIFVQTLIGRVLADDIYMGLRCIAVRKQEIGIGLANRLITFRARPIYIRTPFTCRSTSWICQLCYGRSPTHGDLVELGEAVGIIASQSIGEPGTQLTLRTFHTGGVFTGGTAEHVRAPSSGKIKFNEDLVHRTRTRHGHPAFLCSIGLYVTLEGRDIIHNLNIPPKGLILVQNGQYVESEQLIAEIRAGAFTLNFKERVRKHIYSESEGEMHWSTNVYHAPEYPYGNIHLLLKTSHLWILAGASRRSSIVSFSLHKDQDQMNVHSFSVEERYIYIFDLSMTNHRVKHKLLDTSGKKDREILEYSISDRIISNGHWNLISPSILQDNLDFLAKRRRNRFIIPLQYDQEREKELIPCFDISIEIPINGILRGNSILAYFDDPVYRRSSSGITKYGTLEVDSIVKKEDLIEYRGTKEFNQIQIKVDRFFFIPEEVHILPGSSSIMVRNNSLIGVHTRLTLNTRSKIGGLVRVERKKKSIELKIFSGNIHFPGETDKISRHSGILIPPGTGKKNFNQSKKELKNWIYVQRITPTKKKYFVSVRPVVTYEIADGINLATLFPQDLLQEKDNVQLRVVNYILYGNGKSIRGIYHTSSQLVRTCLVLNWDQEQNDSIEEVHTSFIEVRANDLIRDFIRIDLIKSTISYTGKRNDTGSSGLIPDNGLNSTNINPFYSKSKIQSLTQDQETIGMGTLLNRNKECQSLIILSSSNCSQIGPFNGSKYKNVTKESENIIPIMDFLGSLGTIVPKIANFYSSYHLITHNQILLKRFLLLDNSKQTFQVLKYGLIDENSRIYSPDPCSNIILNPFRLNWCFLRHNYCEETSTIISLGQFFCENICLFKYGPNINIKKSGQIIIVHVDSLVIRSAKPYLVTLGATVHGHYGKILYEGDRLVTFIYERSRSGDITQGLPKVEQVLEVRSIDSISMNLEKRVNSWNECISRILGRPWGFMIGSELTIAQSRISLVNRIQKVYRSQGVQIHNRHIEIIVRQVTSRVLVSEDGMSNVFSPGELIGLLRAERAGRALDEAICYRAILLGITRASLNTQSFISEASFQETTRVLAKAALRGRIDWLKGLKENVVLGGIIPVGTGFQKLVHRSRQDKNIHLEIKKNNLFDLEMRDILLHHRELFCSCIQDNLYETSEQSFTNS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta'', PEP, Plastid-encoded RNA polymerase subunit beta'', RNA polymerase subunit beta''.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: UPPP_THISH
Sequence: MDLFQTLVLALVQGLTEFLPISSAAHLILVPELTDWDDQGLAFDVATHVGSLAAVVIYFRHELRRMTAEWLGSLAGRGLTPDAKLAWAVGLGTIPAGLAGLLFHDIIATHLRSAQVIAMATIGFAVLLLFADVSGKRTRDEHSITWKDVLVIGVAQALALIPGTSRSGITITAALLMGFTRQAAARYSFLLSIPIIALAGGFEILGLVKEPEENIQWGMIVLGALVAGVSAYLCIHYFLKLLAKMTMLPFVIYRLVLGAFLLFLFW
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DB135_PANTR
Sequence: MATRSVLLALVVLNLLFYVPPGRSGPNVYIQKIFASCWRLQGTCRPKCLKNETISYFGVILYICGCVNPKYLPILTGK
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Beta-defensin 135, Defensin, beta 135.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SPTP_SALTI
Sequence: MLRYDERKLNNLTLSSFSKSGVSSDTRLYIAKENTDKAYVAPEKFSSKVLTWLGKMPLFKNTEVVQKHTENIRVQNQKILQTFLQALTEKYGEKAVNNALYMSSINMNKPLTQRLVVQITECVKGADGGFINLIKNKDNVGVMNAALVIKGGDTKVTEQNNDVGAESKQPLLDIALKGLKRTIPQLEQMDGNSLRENFQEMASGNGPLRSLMTNLQSLNKIPEAKQLNDYVTTLKNIQIGADRFSQWGTCGGEVERWIDKASTHELTQAVKKIHVIAKELKNVTAELEKIKAGASMPQTMSGPTLGLARFAVSSIPINQQTQVKLSDGMPVPVNTLTFDGKPVALAGSCPKNTPDALEAHMKMLLEKECSCLVVLTSEDQMQAKQLPAYFRGSYTFGEVHTNSQKVSSASQGGAIDQYNMQLSCGEKRYTIPVLHVKNWPDHQPLPSTDQLEYLADRVKNSNQNGAPGRSSSDKHLPMIHCLGGVGRTGTMAAALVLKDNPHSNLEQVRADFRNSRNNRMLEDASQFVQLKAMQAQLLMTTAS
What is the function of this protein?
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues.  This protein includes tyrosine phosphatase and GTPase activating protein (GAP) activities.  After bacterial internalization, GAP mediates the reversal of the cytoskeletal changes induced by SopE.  This function is independent of its tyrosine phosphatase activity, which remains unclear (By similarity).
What are the official names of this protein?
Secreted effector protein SptP.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the YopE family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Note=Secreted via type III secretion system 1 (SPI-1 TTSS), and delivered into the host cytoplasm.
Protein: JIP5_CANGA
Sequence: MGKKKTSVVQSDELPVIEFRYAEPLFQFVCHPEEPMVVSALATGHVLCHRYDAELLTEKLREARKVQEAVKVEEKKQTLWTVVDVDAADKHPVLPSGVTLLWRTKRHKGSVRALAIDHDGKHVYTIGADNVLKKADTHSGKVVKKVTLDGGSKVTKLVKSATHDFLVMGDEVGTIVVLDSNDLTTKNTLTKIHGGDAINDIFQFCKRSVYKYISLGQTTLAYWDTREPKMKQPKKNSGNQTEEELSNIMCSDDQEDEILCGAFVDPIEGDTLVCGMGEGTLTVWKPKKNDLEDQLTRVKIAKGESIDTVISTLQDDNCVWCGCSNGLLYKVDTKRGKIVEIRKHSGLDEVGMLDLDFEYRLVSGGMDKLKIWEVPKEENSDSDSDSDINDDSEAGLSSSEDSDSDSELGSGSESEVESDASSKSDSDLEECTGSDLPGDIEGSEGENNSNDDDNHDDREELWKELDQPTSDEEEPPKKRSLKVKDKKNKKFKKNENNLSHGITKFDGL
What are the official names of this protein?
WD repeat-containing protein JIP5.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR55 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: SLAE_MACLB
Sequence: MGRFIFVRVGLLVVFLSLSGTGADFDCPPDWSAYDQHCYKAFDEPKRSGDAEKFCTQQANGGHLVSIESVEEAEFVAQLISENIKTSADYVWIGLWNQRKAPYCVSKWTDGSSVIYKNVIERFIKNCFGLEKETNYRTWFNLSCGDDYPFVCKSPA
What is the function of this protein?
Interferes with one step of hemostasis (modulation of platelet aggregation, or coagulation cascade, for example).
What are the official names of this protein?
Snaclec A14, C-type lectin A14.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: RNFA_SHESA
Sequence: MSEYLLLLISTVLVNNFVLVKFLGLCPFMGVSSKLESAIGMSMATTFVLTLASILSYLVNQYLLLPFDLSYLRTMSFILVIAVVVQFTEMVVQKTSASLHRALGIYLPLITTNCAVLGVALLNVNEKHDFIQSAIYGFGAAVGFSLVLILFSAMRERLAAADVPMPFKGGAIAMITAGLMSLAFMGFTGLVK
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit A, Rnf electron transport complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CLPP_RHORT
Sequence: MIDRDPIDVFNNTLVPMVVEQTNRGERSYDIYSRLLKERIIFLTGQVHDGVASLICAQLLFLESENPSKDISFYINSPGGVVTSGMAIYDTMQYIRSPVSTVCIGQAASMGSLLLCAGEAGKRYATPNARIMIHQPSGGFQGQAADIEIQAREILALRERLNRIYVKHTGQPLETIERAMDRDNYMTAEESRAFGLTDSVIERRALSDDGDTKSSS
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIMT_PECCP
Sequence: MVNKRIETLLAQLRQQGIQDERLLKAIEAVPRERFVDEAFEHKAYENTALPIGSGQTISQPYMVAKMTELLSLTPVSRVLEIGTGSGYQTAILAHLVQHVCSVERIKGLQWQAKRRLKQLDLHNVSTRHGDGWQGWASRGPFDAIIVTAAPPEIPRALLEQLDEGGVMVLPVGEQSQILQVVQRHAGEFIIQTVEAVRFVPLVKGELA
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTXL_HOTTS
Sequence: CGPCFTKDPETEKKCATCCGGIGRCFGPQCLCNRGY
What is the function of this protein?
Toxin with unknown function in healthy organisms.  On glioma cells, interacts with chloride channels (probably ClC-3/CLCN3) and MMP2 at the surface of glioma cells.  This complex is then internalized via caveolae, thus inhibiting the chloride channels necessary for cell shrinkage and tumor propagation (By similarity).
What are the official names of this protein?
Chlorotoxin-like peptide Bs 14, Bs14.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Chloride channel inhibitor family.
What are the subcellular locations of this protein?
Secreted.
Protein: GMHA_AROAE
Sequence: MDLIHRISRQFEDSARIKLEALEALAAPIAGAVEIMIGSLLNNGKILACGNGGSAADAQHFAAELVNRFEMERPPLAAIALTTDTSTLTSIANDYDFTQVFSKQVRALGHPGDVLLAISTSGNSPNVIEAIAAAREREMRVIALTGNDGGQIGALLDDGDVHLCVPAQRTARIQEVHLLTLHCLCDGIDCLLLGVEDQ
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPT_BACO1
Sequence: MGLLQEKLAKYDLPQKFMAQGVYPYFREIEGKQGTEVEMGGHEVLMFGSNAYTGLTGDERVIEAGIKAMHKYGSGCAGSRFLNGTLDLHVQLEKELAAFVGKDEALCFSTGFTVNSGVIPALTDRNDYIICDDRDHASIVDGRRLSFSQQLKYKHNDMADLEKQLQKCNPDSVKLIIVDGVFSMEGDLANLPEIVRLKHKYNATIMVDEAHGLGVFGKQGRGVCDHFGLTHEVDLIMGTFSKSLASIGGFIAADSSIINWLRHNARTYIFSASNTPAATASALEALHIIQDEPERLEALWEATNYALKRFREAGFEIGATESPIIPLYVRDTEKTFMVTKLAFDEGVFINPVIPPACAPQDTLVRVALMATHTKDQIDRAVEKLVKAFKALDLL
What is the function of this protein?
Involved in de novo bacterial ceramide synthesis (PubMed:31071294).  Catalyzes the condensation of L-serine with palmitoyl-CoA (hexadecanoyl-CoA) to produce 3-oxosphinganine (By similarity).  Also capable of using alanine as substrate leading to the formation of 1-deoxysphinganine (1-deoxySa) (PubMed:31071294).  Contributes to the levels of endogenous sphingolipids in its host (PubMed:31071294).
What are the official names of this protein?
Serine palmitoyltransferase, SPT.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
Protein: DTD_ECO81
Sequence: MIALIQRVTRASVTVEGEVTGEIGAGLLVLLGVEKDDDEQKANRLCERVLGYRIFSDADGKMNLNVQQAGGSVLVVSQFTLAADTERGMRPSFSKGASPDRAEALYDYFVERCRQQEMNTQTGRFAADMQVSLVNDGPVTFWLQV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 1001R_ASFP4
Sequence: MVRLFRNPIKCIFYRRSRKIQEKKLRKSLKKLNFYHPPEDCCQIYRLLENVPGGTYFITENMTNDLIMVVKDSVDKKIKSIKLYLHGSYIKIHQHYYINIYMYLMRYTQIYKYPLICFNKYYNI
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 100-1R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 100 family.
Protein: RL10_NITWN
Sequence: MERAAKKEAVEQLNETFRTTGVAIVAHYSGLTVAQMQTLRKQMKQAGASVKVSKNRLAKIALEGTDVVAIGSLLKGPTVIATSSDPVAAPKVAVEFAKTNENFVVLGGSMGKTVLDVNGVKALASLPSLDELRGKLVGLLVAPATKIAQLSTAPAAKLARVVQAYASKDEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: GDT1_DICDI
Sequence: MKKILLSIFFVVFLLIGSECELIDTPPGYYNLKKIDKFQQFSKIQIERNNKTIYSSSFHDLFYPDICEGTIQNIPGSLYFGRSSFPGAQESSNLMITRGTKMKYRVGNGGIPIYKINVLCIEGTLEIPEGISFFNVGALFILPGGVLNSKSSIRFTDLDPYNSKMDPFNFFPGMMVLGGSLSLIGEKKRIFQATRIDDYQLQIEDFKKIGSLTNNIYLGSKVTIYSQQISEGQTCSFSFGASNDKINLTSSSSSSLRGTNCLPISKNDKNIIVHFNCKYLLGGSSESFIDSTSTVGSSIYITGDSQVQIENFTLDSIGKTTNKLYNDTKLIFSNDKPNQVIDIIKGENQRFRNSLYIEFSNSVVIKGCAIIDRVKESRAPLIFVSSNVSLSESLIVSKSGSNLIAQYGTEFIKSKLNHYFLIPPLPQPFGLNSPINFPSPFSMDYGFEGNGIYSLSPNVQSINDTFISQLIALNFNFIGNRSIITGFDNDCYSPCTNTSILFSNLIQYPVDFKINNSTYFYKLNNNNNDNNNNTNNFNLLNINNENNNNDDNNNNNNSQNHYLLNINNNGNSPGRFFTIKDLVASDTVSAYLPNSALVFNNLNATENFSFNGTVSRLDFINSSFNTNLTSTQKFFDETTTTVTNFQNTYIYGSPETTEPPEKVFGSSITPIYYFSKSVLDSLKVETVYPNEPHKMFFNSSVSLSVKLNNMGLKTPIICIFSSNGMESKEVQYNPISTKCSFLYVSEKLGNHNIRVTIKNEYSKDSSYYFIIDFPIITVYGQSLFNAGWQMIDPTSTTIIPTPTPTSTSTSTSTSTPTTTNNNQLVNDNNNKINELDGLKFQGGCIKTLGCQLSSNAKYVGGLPNVTASSTLNSLFSWGITSDVQYDPVIIDLFINKSIATLQVQLFFTFYKPIDQYSSPLSVSIQKNPVLVMEPFAGDQPFSKNLTFVYNNTQSLDFLNISFTSRGDIYLTSLAIFSVSDSLPQIIDPITPTLLPIESVKASKPAILAIVLSIVLGSLALSIITILIVKHRKRLSQFLSKSNKDIEYAQNNEIEIKVLPKITSHSSYPSISILDTISSDSIFNNQIPKNNNRYKFKNQSLNNNNYFNNNNNNNNSNNNNSNNIIYSNCNSNYSNSNSNNNNNNNNSNSNNNSNSNSNININSNSNSNSNSNSNGNNNYQIYSNKLESFKIDEISNDTIPIINSTFPDEFQTLEFQKLAFEILKREKRLDFSFRTTNDILTCCALSDFKDFSNFPLRFNQSIITFGLINGKAKLGETYYDTLSITNDSTIRFTAFLILPMDNHSATFTSDHSSFDLGPGETFSIKFSITLHCTTRFFENFSIQINSNNIKEMYTLLKIKVESESSTRLDFNDIHFQELIEKYSWEILYRGTVGDKNALLKLIKLKTKNCEEAYRELNIISRLKHQNILPLIGCVISKDYLCLAFEYPPLGSLDYIISKKKLKMSITQKIRILIDVAKGCKFLQQSSIIQKTLRARNIFLYDTNENAEVCAKVLDLTSSKTIKGLACNNYIERVDTPINLTREISIIRDPKQNNDFNNSNNSNNNNNNNNNNNNNNNNNSNNSNNSSSLKYNIHSFAVLSYELLIDEILVGDTRKFGQEKPSIGLDKIDPNIKNFIHKCWNPIDGFTFNEILKTLKDFIESLN
What is the function of this protein?
Regulates the transition between growth and differentiation.
What are the official names of this protein?
Probable inactive serine/threonine-protein kinase gdt1, Growth-differentiation transition protein 1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: UBIQA_DICDI
Sequence: MQIFVKTLTGKTITLEVEGSDNIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEGSDNIENVKTKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEGSDNIENVKTKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEGSDNIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEGSDNIENVKTKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGN
What is the function of this protein?
Ubiquitin exists either covalently attached to another protein, or free (unanchored).  When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains).  Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involved in protein degradation via the proteasome.  Linear polymer chains formed via attachment by the initiator Met lead to cell signaling.  Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed.  When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling (By similarity).
What are the official names of this protein?
Polyubiquitin-A.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ATS3_ARATH
Sequence: MTFPSLSVSFLFFAFIFVTHAFDLSIIQMQQGTCPYTVVVMTSCLSPESTRDQISIVFGDADGNKVYAPKLGGLVRGPGGLGKCSTNTFQVRGQCLNDPICSLYINRNGPDGWVPESIEIYSEGSKSVKFDFSKSVPQLNTWYGHNNCNTTGRPSSPDLPPPHFPPEFPPETPTTPPPPPPRPSAASRLGNGESVFLAFAIATAIAAMVRWSY
What is the function of this protein?
May play a role during embryo development.
What are the official names of this protein?
Embryo-specific protein ATS3, Protein ARABIDOPSIS THALIANA SEED 3.
What are the subcellular locations of this protein?
Secreted.
Protein: SFNG_PSEPF
Sequence: MSQQAVKFAYWVPNVSGGLVVSRIEQRTDWGIDYNRKLAQLAEAAGFEYALTQIRFTAGYGAEFQHESVAFSHALLAATSQLKVIAAILPGPWQPALAAKQLATIDQLTNGRIAVNIVSGWFRGEFQAIGEHWLEHDERYRRSEEFIRSLRGIWSQDNFTFRGDFYRFDNYSLKPKPLGRPEIFQGGSSRAARDMAARVSDWYFTNGNSVEGIKAQVDDIRAKAAANHHSVKIGVNAFVIARDTEEEAKAVLAQIIDQADPEAVNAFGDAAKQAGRASPEGEGNWAKSTFEDLVQYNDGFKTNLIGTPQQIAERIVALKAVGVDLVLAGFLHFQEEVEYFGQRVLPLVRELEAKAQSARTAEVA
What is the function of this protein?
Involved in the dimethyl sulfide degradation pathway.  Catalyzes the oxidation of dimethylsulfone (DMSO2) to yield methanesulfinate, which is oxidized spontaneously to methanesulfonate in the presence of dioxygen and FMNH(2).
What are the official names of this protein?
FMNH(2)-dependent dimethylsulfone monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the SsuD family.
Protein: PYLS_METAC
Sequence: MDKKPLDTLISATGLWMSRTGMIHKIKHHEVSRSKIYIEMACGERLVVNNSRSSRTARALRHHKYRKTCRHCRVSDEDINNFLTKTSEEKTTVKVKVVSAPRVRKAMPKSVARAPKPLEATAQVPLSGSKPAPATPVSAPAQAPAPSTGSASATSASAQRMANSAAAPAAPVPTSAPALTKGQLDRLEGLLSPKDEISLDSEKPFRELESELLSRRKKDLKRIYAEERENYLGKLEREITKFFVDRGFLEIKSPILIPAEYVERMGINSDTELSKQVFRIDKNFCLRPMLAPNLYNYLRKLDRALPDPIKIFEIGPCYRKESDGKEHLEEFTMLNFCQMGSGCTRENLEAIITEFLNHLGIDFEIIGDSCMVYGNTLDVMHDDLELSSAVVGPVPLDREWGIDKPWIGAGFGLERLLKVMHGFKNIKRAARSESYYNGISTNL
What is the function of this protein?
Catalyzes the attachment of pyrrolysine to tRNA(Pyl).  Pyrrolysine is a lysine derivative encoded by the termination codon UAG.
What are the official names of this protein?
Pyrrolysine--tRNA ligase, Pyrrolysine--tRNA(Pyl) ligase, Pyrrolysyl-tRNA synthetase, PylRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_HELMI
Sequence: MTEYVAGKYDVIVIGAGHAGCEAALASARLGAKTLILTISWDNVALMPCNPAIGGPAKGHLVREIDALGGQMGLTIDKTCIQIRLLNTGKGPAVHALRAQADKKRYQREMIRVLEHQENLDVRQAMVESVVVEQGRVRGIRTNTGAFFAAPALVITTGTYLRGRIIIGDLHYPGGPNGYFPSVALAASLRDIGVRLGRFKTGTPARVDGRTVDFSQMVEQPGDREPLNFSFLSPRIERKQISCWLTYTTEETHQIIRDNLHRSPLYAGVIEGTGPRYCPSIEDKVVRFADKKSHQVFIEPEGEGTHEMYVQGMSTSLPEDVQVTMLRSIIGMKDVKIIRPGYAIEYDYVDPTQLRLSLEHQEIGGLFTAGQINGTSGYEEAAAQGLMAGINAARFVKGEEPLVLKRSDAYIGVLIDDLVTKGTNEPYRMLTSRAEYRLLLRQDNADQRLTEIGRSIGLVDDRRYRRFREKMQLLEQEVVRWKSSFVTPGNKKIQAILDEKKSAPLTKGVSLYDLLRRPELTYDDLIPLCNDGEKDLPIDPEVAEQVEISAKFEGYLVKQQAQVDRFNKLENKRLPADLDYKRVHGLSNEGRQKLIARKPVSIGQASRISGVSPADISILLVYLEQQRRLAPGEGGVD
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C78AB_ORYSJ
Sequence: MAMATATASSCVDATWWAYALPALLGADTLCAHPALLAGAVLLAFATAAVLAWAASPGGPAWAHGRGRLGATPIEGPRGLPVFGSIFALSRGLPHRALDAMSRDAAAPRARELMAFSVGETPAVVSSCPATAREVLAHPSFADRPLKRSARELLFARAIGFAPSGEYWRLLRRIASTHLFSPRRVAAHEPGRQADATAMLSAMAAEQSATGAVVLRPHLQAAALNNIMGSVFGRRYDVSSSSGAAADEAEQLKSMVREGFELLGAFNWSDHLPWLAHLYDPNHVARRCAALVPRVQAFVRGVIRDHRLRRDSSSTAADNADFVDVLLSLEAHENLAEDDMVAVLWEMIFRGTDTTALVTEWCMAEVVRNPAVQARLRAEVDAAVGGDGCPSDGDVARMPYLQAVVKETLRAHPPGPLLSWARLATADVGLANGMVVPAGTTAMVNMWAITHDGEVWADPEAFAPERFIPSEGGADVDVRGGDLRLAPFGAGRRVCPGKNLGLATVTLWVARLVHAFDWFLPDGSPPVSLDEVLKLSLEMKTPLAAAATPRRRRAA
What is the function of this protein?
Involved in the regular timing (plastochron) of lateral organs formation.  May regulate the rate of leaf initiation and the duration of vegetative phase.  Seems to be redundant to the function of PLASTOCHRON2, but to act in an independent pathway.
What are the official names of this protein?
Cytochrome P450 78A11, Protein PLASTOCHRON1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SECY_ECOL6
Sequence: MAKQPGLDFQSAKGGLGELKRRLLFVIGALIVFRIGSFIPIPGIDAAVLAKLLEQQRGTIIEMFNMFSGGALSRASIFALGIMPYISASIIIQLLTVVHPTLAEIKKEGESGRRKISQYTRYGTLVLAIFQSIGIATGLPNMPGMQGLVINPGFAFYFTAVVSLVTGTMFLMWLGEQITERGIGNGISIIIFAGIVAGLPPAIAHTIEQARQGDLHFLVLLLVAVLVFAVTFFVVFVERGQRRIVVNYAKRQQGRRVYAAQSTHLPLKVNMAGVIPAIFASSIILFPATIASWFGGGTGWNWLTTISLYLQPGQPLYVLLYASAIIFFCFFYTALVFNPRETADNLKKSGAFVPGIRPGEQTAKYIDKVMTRLTLVGALYITFICLIPEFMRDAMKVPFYFGGTSLLIVVVVIMDFMAQVQTLMMSSQYESALKKANLKGYGR
What is the function of this protein?
The central subunit of the protein translocation channel SecYEG.  Consists of two halves formed by TMs 1-5 and 6-10.  These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back.  The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug.  The plug probably moves laterally to allow the channel to open.  The ring and the pore may move independently.
What are the official names of this protein?
Protein translocase subunit SecY.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.