PharMolix/UniProtQA huggingface dataset:
Protein: RSMA_CYTH3
Sequence: MEKVKAKKHLGQHFLNDQQIAQDIVDGLTLHGSYKEVLEIGPGMGVLTQYLLKNNSYHTKVVDIDGESIEYLKKVFPQLKDDVIHGDFLKADLADWYPDKFAIIGNFPYNISTEILFKVLDYREQIPEVVGMFQKEVAERFAAKNGNKTYGITSVLLQAFYDIEYLFTVPEHVFTPPPKVKSGVIRLKRNNRTHLPCDEKEFFKVVKAGFNMRRKTLRNALKSINVQNISMDLPIFDKRAEQLSVQEFFDLTNMLSGK
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCB1_YEAST
Sequence: MADQVPVTTQLPPIKPEHEVPLDAGGSPVGNMGTNSNNNNELGDVFDRIKTHFPPAKVKKIMQTDEDIGKVSQATPVIAGRSLEFFIALLVKKSGEMARGQGTKRITAEILKKTILNDEKFDFLREGLCVEEGQTQPEEESA
What is the function of this protein?
Component of the NC2 complex which represses RNA polymerase II transcription through binding to SPT15/TBP and thereby inhibiting the assembly of the preinitiation complex.  The NC2 complex may also mediate transcriptional activation from TATA-driven promoters through association with SPT15/TBP.
What are the official names of this protein?
Negative cofactor 2 complex subunit alpha, NC2 complex subunit alpha, Transcription repressor BUR6.
What is the protein family that this protein belongs to?
Belongs to the NC2 alpha/DRAP1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YTJA_ECOLI
Sequence: MFRWGIIFLVIALIAAALGFGGLAGTAAGAAKIVFVVGIILFLVSLFMGRKRP
What are the official names of this protein?
UPF0391 membrane protein YtjA.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CTL12_ANOGA
Sequence: MGLCCGSTDRVTKYSKEDIQQPTESEPLKYDPDFKGPLSKRSCTDLPCLFLFVTFLCAWGYVAYYAVQHGDLNRLLVPIDSDGRKCGVDSEVRDEPYLVFFNITECAKIDVPISGCSTTQVCVSQCPNQDFDFESANCNPSNVNEIRSKLICKQNVKKSDLTTCQIIRQYIKSQRCAQTMQKSTPLVNRCVSNIPEGQCTLIPKQFRQQPPITSTKFQTSAEQCKEQRELENILEEKISKLQSFLARYVNNLISVLTKNNSVHQLKYLNYHLVLQTLKKGNLKHNPLIITPYLITIHNITVLLTFQMIVEDILESWRMILVFIACSVLASLILIAMLRWIAKPLVWISIIGVITALSYGVYYSFRQYQQIRANPVAAHVNVSPNLSSLVNSWFKSDQTWLWILIALSVILIVLLLVVLVLRKRIVIAIALLKEGSKAVSASFSTVFFPLVPWILQAVVIVFSLLVLLFLASIGVPVYKVNGLNSSLTCVCTNGYMEGDICDPVAFNENCRDTSRIYDQERCLDAACHFQEVDTPGIVRFFHALNVIGFFWCICFVSAFSEMVLAFTFATWYWTRQKSRLPFFVLTRGVTHTVYYHLGTLAFGSLIIAICKIIRAILEYVDHKLKRYDNGFTRAVLCCCRCFFWCLESFLKFLNRNAYIMCAIYGKNFCSSAKDAFSLLTRNVLRVIALDKVTGFLFFLSKLLLASGMAAVTYTYFDSDLPKMQLNYPFVPAVLVFIGTFIIASIFFSVYSVAVDTLFLCFLEDIERNDGSAERPFYMSRGLQKILGKKQK
What are the official names of this protein?
Choline transporter-like 2.
What is the protein family that this protein belongs to?
Belongs to the CTL (choline transporter-like) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: BIOB_HELHP
Sequence: MQKISNEIFLCSICNVSSGDCPEDCKYCTQSAHYGTQIQRYKNKSIDKIVQEAKTLREYGALGFCLVTAGRSLESQKCEYIAKAASAIKKADLGLHIIACCGSADVDSLKYLKTNGVDSYNHNLETSKEFFPHICTTHTWKERFETCENTLKAELGLLSGGIFGLGESWGDRIELLKHLQILSPHTSPLNFYIANESLPLPMQTLSPQEALECVTLAREYLPNTRLMIAGGREAVFGDNQKPLFEAGINGVVLGDYLTTDGKAPKDDVAMIESYGYVAATNCH
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: CYB_SARSA
Sequence: MASLRKTHPLLKIANDALVDLPTPSNISAWWNFGSLLGLCLISQILTGLFLAMHYTPDVESAFASVAHICRDVNFGWLIRNLHANGASFFFICIYFHIGRGLYYGSYLYKETWNIGVVLLLLVMMTAFVGYVLPWGQMSFWGATVITNLLSAVPYVGTTLVEWIWGGFSVDNATLTRFFAFHFLFPFVILAMTILHLLFLHETGSNNPIGLNSNADKISFHPYFSYKDLLGFAILLVALASLALFSPNLLGDPDNFTPANPMVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLASILVLMVVPFLHTSKQRTLTFRPVSQFLFWTLIADVAILTWIGGMPAEQPFIIIGQVASVLYFSLFLVFFPLAGWAENKILGWS
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CK2N2_BOVIN
Sequence: MSEILPYSEDKMGRFGADPEGSDLSFSCRLQDTNSFFAGNQAKRPPKLGQIGRAKRVVIEDDRIDDVLKGMGEKPPSGV
What is the function of this protein?
Potent and specific cellular inhibitor of CaM-kinase II (CAMK2) (By similarity).  Traps Ca(2+)/calmodulin on CAMK2 (By similarity).
What are the official names of this protein?
Calcium/calmodulin-dependent protein kinase II inhibitor 2, CaM-KII inhibitory protein, CaM-KIIN.
What is the protein family that this protein belongs to?
Belongs to the CAMK2N family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol. Synapse. Note=Excluded from nucleus when coexpressed with activated CAMK2.
Protein: HIS2_METB6
Sequence: MTHEGKEPVDLRVIRELWGVICERADCPDENSYTSRLLQDVKGIDKVLEKVGEESTEFILAVKNGVPERTTEEAADLFFHVLVALRAADVDLSGVIRELERRRK
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PER37_ARATH
Sequence: MHSSLIKLGFLLLLIQVSLSHAQLSPSFYDKTCPQVFDIATTTIVNALRSDPRIAASILRLHFHDCFVNGCDASILLDNTTSFRTEKDAFGNANSARGFDVIDKMKAAVEKACPKTVSCADLLAIAAQESVVLAGGPSWRVPNGRRDSLRGFMDLANDNLPAPFFTLNQLKDRFKNVGLDRASDLVALSGGHTFGKNQCQFIMDRLYNFSNTGLPDPTLDKSYLSTLRKQCPRNGNQSVLVDFDLRTPTLFDNKYYVNLKENKGLIQSDQELFSSPDASDTLPLVREYADGQGKFFDAFAKAMIRMSSLSPLTGKQGEIRLNCRVVNSKSKIMDVVEDALEFASSM
What is the function of this protein?
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.  These functions might be dependent on each isozyme/isoform in each plant tissue.
What are the official names of this protein?
Peroxidase 37, Atperox P37, ATP38.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.
What are the subcellular locations of this protein?
Secreted. Vacuole. Note=Carboxy-terminal extension appears to target the protein to vacuoles.
Protein: TRMB_EXIS2
Sequence: MRLRHKPWALDYMKEQSSIYIADPSTLKGNWSNEFKNENPIYIEVGSGKGAFITGMAKQYPEVNFVAIELFESVAVAIVQKMVEEPLANVRVLTVDAKDLRDFFEKGEVARVYLNFSDPWPKSRHAKRRLTYKTFLATYEDILPEKGQIHFKTDNRKLFESSLMTMSAYGMTFDWMSLDLHANEPENNVRTEYEERFSAMGQPIYRMEATYTK
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: YTFK_ECOLI
Sequence: MKIFQRYNPLQVAKYVKILFRGRLYIKDVGAFEFDKGKILIPKVKDKLHLSVMSEVNRQVMRLQTEMA
What are the official names of this protein?
Uncharacterized protein YtfK.
Protein: MDM34_KLULA
Sequence: MSFKFNSGTFEDNTFNEQIRDRLTRALNPSRFENPESTSGQDGSDSQKKPKKLDILKSGVTVRQVDFRTIPQLEILDLDVSAQSKSLLKGICKISCKDAMIQITTEIEANLLLLYEAVSPEFTTPKLISNDSFTVPITMTFDHIELEAITNIFVKNTGVGISFNDVNLDFRFECSMKLLQTSIEKRLKNSMETIFKDVLPSVIFNMSQRWFTHGPELVEDPSLIATDSALSEVTPMTILDDSDLQDLSPATMLRLSTLISSRQSLALNPISSHTVATIPGCIERQNLRRFSSRIPSLNNYYAQEVGKHRPSKILPTRENSNSIIANKMASDFIQNSLPTEVLESGSYNIREIANIQQRIYERNNEENVIRRRRIRLGKRSKSVQDTAAKMHPVPESGSLHPIIQPSTTPAATVTPLLSPQPVVAKSPPESMTPNTLPEQSPYTSNIAIDKIPDLTLPQAQLQKDKVPMRLNLLEESYFKSDLKDLRNSLYSPMRNQRFYVQSEDGARPSLLDGKRFSFVGLANQQMKWGNDDLPPPYKAN
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 34.
What is the protein family that this protein belongs to?
Belongs to the MDM34 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria- endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: RS14Z_STAA1
Sequence: MAKTSMVAKQQKKQKYAVREYTRCERCGRPHSVYRKFKLCRICFRELAYKGQIPGVRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: PUR7_BACCR
Sequence: MQKLELLYEGKAKRIYRTESADMVWVEYKDSATAFNGEKKETITGKGRLNNEITTLLFRKLQEVGIKTHFVEKLSETEQLVKKVSIIPLEVVTRNVIAGSLSKRLGMEEGTVLAEPIVEFYFKDDDLGDPLVTEDHIRVLNVASPEQVSVLRDMALQINQVLIDHFASCRVRLVDFKLEFGVTEEGEIILADEISPDTCRLWDETSNEKFDKDVFRRDLGNLTDAYEEILKRLGGISHV
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: Y5418_PSEFS
Sequence: MTDKEVKAPKIEFPVVDYPIKVISDTGVGRKDLILEIVRKHATINDQRVDERSSSTGKYTTIQLHIVATDQDQLYNINSELRATGFVHMVL
What are the official names of this protein?
UPF0250 protein PFLU_5418.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.
Protein: GLGC_SALPB
Sequence: MVSLEKNDRVMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCLNSGIRRIGVITQYQSHTLVQHIQRGWSLFSEEMNEFVDLLPAQQRMKGENWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIKEATAFGVMAVDESDKIIDFVEKPANPPAMPGDASKALASMGIYVFDADYLYELLAADDKDDASSHDFGKDIIPKITREGMAYAHPFPLSCVQSDPQAEPYWRDVGTLEAYWKANLDLASVTPELDMYDQNWPIRTHMESLPPAKFVQDRSGSHGMTLNSLVSGGCIISGSVVVQSVLFPRVRINSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACIIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLQVKQER
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: SYI_RICB8
Sequence: MTNTKYYPEVSSNADFATIEKEILKFWQDNNIFQKSIDIREGDAEFIFYDGPPFANGLPHYGHLLTGFIKDVYARYQTVRGKKVERRFGWDCHGLPAEMQSEKELGISGHLAITNFGIEKFNAHCRDSVMKYAGEWEQYVTRQARWVDFKNSYKTMDKNFMESVLWAFKELYNKGLLYESMRVMPYSWACETPLSNFETRLDNSYRERADKAVTVSFVLCHPVSKSTLDVIPWLDHGIQKTINNDSANCSMDPVDKPRYDTENFLGITANYKEYRILAWTTTTWTLPSNLALAVGSDIDYALVPKGDVCYIIAASSVSKYAKELELKGDEQFTIIKGSELQGLSYKPLFDYFKNHPNSFKIFAGDFVVEGDGTGVVHMAPGFGEDDQILCESKGIKLVCPVDNSGKFTKEIPDLEGLQVFDANDKIIIKLKEQGNWLKTEQYIHNYPHCWRTDTPLIYKAVPSWYVKVTEFKDRMVELNQQINWIPTHVKDNLFGKWLENARDWSISRNRFWGTPLPVWKSDDPKYPRIDVYGSIEELEKDFGVKITDLHRPFIDELTRANPDDPTGKSTMRRIEDVFDCWFESGSMPYGQAHYPFENKQWFEEHFPADFIVEYSAQTRGWFYTLMVLSTALFDRPPFLNCICHGVILDATGQKLSKRLNNYADPLELFDKYGSDALRVTMLSSNVVKGQELLIDKDGKMVFDTLRLFIKPIWNAYHFFTMYANADHIKGELNFTSENVLDVYILSKLKIAVEKIKESLDSFDTGTAYHAVSEFFEVLNNWYIRRSRARFWKSEKDADKQSAYNTLYTCLETMAIAMSSLVPLISEAIYLGLYCHPRKSGDPEKPECLDSRLCGNDNLSVHLCDYPDLSKFKINSELVDTMDTVLDICNHSLFIRSSENARVRQPLSSITIISKNNDKLKSFEDLIKDEINVKSVIYRDDLENYAVKKLSINFPLLGKRLPAKMKDIIAASKKNEWEVTSGSLIICNETLNSDEYKLILEPHSHIKGASSFAHNSSLLILDLELTPELIDEGIARDIVRFIQQARKNADFAITDRILIDINLPKITDIYGEFIKEQTLGKFAKDFIPDHISEIELDNHKLQLKIKKVN
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_BURMA
Sequence: MPRRREVPKREVLPDPKYGNVDVAKFMNMLMLSGKKSVAERIVYGAFEQIQTKGGKDPLEVFTVALNNVKPVVEVKSRRVGGANYQVPVEVRPSRRMALAMRWLREAAKKRSEKSMALRLAGELSEAAEGRGGAMKKRDEVHRMAEANRAFSHFRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: MUTL_BACC3
Sequence: MGKIRKLDDQLSNLIAAGEVVERPASVVKELVENSIDANSTSIEIHLEEAGLSKIRIIDNGDGIAEEDCIVAFERHATSKIKDENDLFRIRTLGFRGEALPSIASVSELELITSTGDAPGTHLIIKGGDIIKQEKTASRKGTDITVQNLFFNTPARLKYMKTIHTELGNITDIVYRIAMSHPEVSLKLFHNEKKLLHTSGNGDVRQVLASIYSIQVAKKLVPIEAESLDFTIKGYVTLPEVTRASRNYMSTIVNGRYVRNFVLMKAIQQGYHTLLPVGRYPIGFLSIEMDPMLVDVNVHPAKLEVRFSKEQELLKLIEETLQAAFKKIQLIPDAGVTTKKKEKDESVQEQFQFEHAKPKEPSMPDIILPTGMDEKQEEPLAVKQPAQLWQPPKQEWQPPQSLVREEQSWQPSTKPIMEEPIREEKSWDSNEEDFELEELEEEVQEIEEIEMNGNDLPPLYPIGQMHGTYIFAQNDKGLYMIDQHAAQERINYEYFRDKVGRVAQEVQELLVPYRIDLSLTEFLRVEEQLEELKKVGLFLEQFGHQSFIVRSHPTWFPKGQETEIIDEMMEQVVKLKKVDIKKLREEAAIMMSCKASIKANQYLTNDQIFALLEELRTTTNPYTCPHGRPILVHHSTYELEKMFKRVM
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: REEP5_RAT
Sequence: MSAAMRERFDRFLHEKNCMTDLLAKLEAKTGVNRSFIALGVIGLVALYLVFGYGASLLCNLIGFGYPAYISMKAIESPNKDDDTQWLTYWVVYGVFSIAEFFSDLFLSWFPFYYMLKCGFLLWCMAPSPSNGAELLYRRVIRPIFLKHESQVDSVVKDVKDKAKETADAISKEVKKATVNLLGDEKKST
What is the function of this protein?
Plays an essential role in heart function and development by regulating the organization and function of the sarcoplasmic reticulum in cardiomyocytes.
What are the official names of this protein?
Receptor expression-enhancing protein 5, Polyposis locus protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the DP1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Sarcoplasmic reticulum membrane; Multi-pass membrane protein. Note=Localizes to endoplasmic reticulum tubular network. In cardiomyocytes, localizes to the junctional sarcoplasmic reticulum membrane which is closely tethered to the cell membrane and contractile machinery.
Protein: ARLY_LACE2
Sequence: MKLWGGRFTKETNELVNNFNASISFDQKFYKQDIEGSIAHATMLGKQGIIPESESEQIVEGLKGILADIESGKLEITDEYEDIHTFMEATLIERIGDAGKRLHTGRSRNDQVALDMRLFTRQEVLNTDAELKELMAVILRIMKENTHTFMPGFTHLQKAQPVTVAHHFGAYFEMFKRDRSRLHDIYERMNYCPLGAGALAGTTYPLDRELTASLLGFYGPTLNSMDSVSDRDYLIEFLSALSTIMMHLSRFSEEICIWNSNEYRFIELDDAFSTGSSIMPQKKNPDIAELVRGKTGRVYGALISLLTTMKGIPLAYNKDMQEDKELSFDAFDTAKGCISLFKGMIDTMKFNNKRMEASAKNGFTNATDAADYLVKKGVPFREAHGIVGQLVLMCIEKNIALDDLSLDEYKAVSPVFDEDIYEAISLQTCVDKRLTLGAPGPEVMNKVIAIYDKYMEEN
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y7891_DICDI
Sequence: MSDTHDDRVKQLVEFLDPLVDDSFKIKFNELSKYSKEELKQHTQKLEDWALALGVAEQKQLQTGRLLGIISDFNEFNCENTNHHQQQQNHQNQQQQQQQPNGIFENNI
What are the official names of this protein?
Putative uncharacterized protein DDB_G0274333.
Protein: MFAP3_BOVIN
Sequence: FRTEGAEKLQKAFEIAKRIPIITSAKTLELAKVTQFKTMEFARYIEELARSVPLPPLILNCRAFVEEMFEAVQVDDPDEMGERIKERPALNAQDGIFVINPEMGRSNSPGGDSDDGSLSEQGQEIAVQVSVHPQSETKSIDTDSQDSSHFSPPDDTGSTESNSNYKDGSFESCQL
What is the function of this protein?
Component of the elastin-associated microfibrils.
What are the official names of this protein?
Microfibril-associated glycoprotein 3.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: TRYS_TRYCC
Sequence: MPTLQSLAVPFGCVQGYAPGGIPAYSNKHESYFSGERSIDGNLFCGFKYQCVEFARRWLFERKSLVLPDVDWAVHIFNLKEVSDARTGKPVRCVAIRNGTAAKPVVDSLLIYPSDDYSPVGHVAAITEVGDKWVRIADQNHRFHKWDANYAAELPLIHEKGVWTILDPLEDEVLKPLGWVTFPDTPDRNPNEPLVLHESLHFKRGELPTLRRLTFTPTSREKDWLDLTNEAEAYFADVCGIDVKNPKLEKASYYQMNRELYLDCAKYGNQLHQMFLEATKFVLGSDELLRLFCIPEEYWPRLRHSWETQPHAITGRFDFAFDEDTQQFKCFEYNADSASTLLECGVIQQKWARSVGLDDGTTYSSGSLVSSRLQLAWEMAEVTGRVHFLIDNDDEEHYTALYVMQHASAAGLETKLCVLFDEFHFDENGVVVDSDGVAVTTVWKTWMWETAIADHQKARVQRGNDWRPTPKDEVRLCDILLGPNWDLRVFEPMWKIIPSNKAILPIIYNKHPDHPALLRASYELTVELQRTGYVRKPIVGRVGRNVTVTEASGDIAAKSDGDFSDRDMVYQELFRLPERDGYYAILGGWVIGDVYCGTGVREDKTIITGLESPFSALRVYQGAQRRPLTHEDLDKAEAAAVGGGLKT
What is the function of this protein?
Bifunctional enzyme which catalyzes the formation of trypanothione (N(1),N(8)-bis(glutathionyl)spermidine) from glutathione and spermidine.  Converts spermidine or glutathionylspermidine into trypanothione.  Can also convert aminopropylcadaverine into glutothionylaminopropylcadaverine and homotrypanothione.  Also has low amidase activity, hydrolyzing trypanothione, homotrypanothione or glutathionylspermidine to form glutathione and the corresponding polyamine.
What are the official names of this protein?
Trypanothione synthetase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the glutathionylspermidine synthase preATP-grasp family.
Protein: RUVA_BAUCH
Sequence: MIGRLRGIILEKQPPLLLLEINGIGYEIAIPMNNFSLLPAIGQETILYTHCIVREDTELLFGFIKKPDMILFRALIKINGVGPKLALAILAGMSEKQFLSAIEHNEIHMLTKLPGVGKKTAERLVIEMKDKLKGTSKSLFSLATIGEGLAKTEIEAITALISLGYTHQEASKMVKKVAIEGANCETLIRDALRTTL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: SURE_PORGI
Sequence: MKADPIEILVSNDDGFRAQGIRELAEALRPLGNVTIVAPDGPRSGASAAITSTLPIKLKLRHREEGYTVYSCTGTPVDCVKLAMNTVFKERKPDLLVTGVNHGNNAGICVIYSGTVGAAMEGCVCDVPALAVSLDDHSEICDMSHATAYAVHVSRMILKNGLPQDTMLSMNVPKGKPLGLKPCAVTDGRFVDEYMASEDARGNAVYWMTGRQINKGTIEGDLELMHAGYVTLSPIKLNMTSRRYLPVLEELLKRSV
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECD_DESIS
Sequence: MDGKLIAKLLLIAAVIGFCIHLATPLNEKIALGLDLQGGMHLALDVDTEQAVERKLDAMTNALRLEAQQQHLVIGTIQRRGMQILIPVPYAEEKAEFKRLMQRRYGQLELQDEQPELLVYGYTTYDIEEIKELAVGQALETIRNRIDQFGVSEPTVQKQGDRRIIIELPGVEDVDRAVELIGRTAMLEFRLVNENVSTRDALDGFLPENSEVLYQRHMDPQTNTEVDRTPFVLYRDVIFTGDRLLDARVRFDPQFNTPYVSITLDGEGARLFADVTGRNVGRRLAIVLDGHVHSAPVINERIPSGQASISGQFTMEQATDLSIVLRSGSLPAPVDIVENRTVGPTLGQDSIDKGILSVTIGMALVLLFMVAYYRLSGLLANMALLMNLIILMGLLAYFGATLTLPGIAGIILTIGIAVDANVLIFERIREELRRGASPRLAIEEGYAKAFSTILDANITTLIVAVILFQFGTGPIKGFAVTLSIGILASMFTAILCTRAIYELILVYKPIRKLSI
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
What are the official names of this protein?
Protein translocase subunit SecD.
What is the protein family that this protein belongs to?
Belongs to the SecD/SecF family. SecD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS1_VIBCH
Sequence: MQTQRLRIAIQKKGRLSQECQELLKKCGVKFNIMGERLVVHSLNMPIDLLLVRDDDIPGLIMDGVVDLGFVGENVLEETRLDRLALNQRNEFTTLRRMDFGGCRLSIAIEKDAEYRGPQDLNGKRIATTYPQLLKAYMDRQGVDFSTCMLTGSVEVAPRAGLADAIADLVSTGATLEANGLKEVEVIFESKATLIQRPGAFAADKAALIDKLLTRMHGVQQAKESKYIMLHAPVEKLAQIKTLLPGAEDPTVLPLSADKSKVAVHMVSSENLFWETMEQLKALGASSILVLPIEKMME
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity).
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIBBA_SALAI
Sequence: MTTFGTIEQAMAEIVAGRPVVVVDDANRENEGDLIFAAELATPELVAFMVRYTSGYICAPLTEDECDRLDLPPMHHTNQDRRGTAYTVTVDAREGVSTGISAADRAHTIRLLADPRTGPADLARPGHVVPLRARQGGVLRRPGHTEAAIDLTRLAGLRPAGVLCELVNDDGTMMRVPDLERFCAEHSLVLITIADLVAYRRRTEKQVELVAEARMPTRHGVFRAFGYRSDYDSAEHVALVMGDLGDGRDVLVRVHSECLTGDVLGSLRCDCGPQLNAALDQVAREGRGVVLYVRGHEGRGIGLLHKLQAYQLQDTGRDTVDANLDLGLPADARDYGTGAQILYDLGVRSMRLLTNNPAKRAGLEGYGLTVAGRVELPVRPHPENVRYLRTKRDRMGHLLEFDEVIEAPMGRAVVGDGIGA
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
Riboflavin biosynthesis protein RibBA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the GTP cyclohydrolase II family.