PharMolix/UniProtQA huggingface dataset:
Protein: LEXA_BORA1
Sequence: MATKLTERQQEILDLIRQTVARTGFPPTRAEIAQALGFRSPNAAEDHLKALARKGAIELTAGASRGIRLKDAEPTPSPILASLSQLLLPLVGRVAAGSPILAAEHVEREVGVDPSLFSQAPDYLLKVRGMSMRDAGILEGDLLAVKKSSEARNGQIIVARLGDDVTVKRLQRHGSRIELLPENPEFSPILVAPDDEFALEGVAVGLIRTHALH
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: ARLY_EXIS2
Sequence: MTKLWGGRFTESASAQAEAFGASISFDQKLAAVDLQGSLAHAQMLYEQGILEKTEWEQIEAGLKQLQTTLEQHVYTTVDEDIHMNLERLLTEQIGPVAGKLHTARSRNDQVATDLHLWMEQHVLELLSSLRNLQSVITEQAEQHVETVMPGYTHLQRAQPISLAHHLLAYFWMFERDADRLTDNLKRIRMSPLGAGALAGTTFPIDRFKSAELLGFEQVYPNSLDAVSDRDFVIEYLGIASTVMMHLSRFCEEIIIWASQEFSFIELSDAFSTGSSMMPQKKNPDFAELIRGKTGRVYGNLMGFLTTMKALPLAYNKDMQEDKEGVFDTADTVLQSVQIFTGMIESATFKTEALKKATMQDFSNATELADYLVTKGIPFREAHEIVGKAVLHCVQSGCFLKDLTLSTYQTFHPVIAEDVYPLLDPVQAVARRGSYGGTGFTAVRDQLALAKKQLEKL
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_STRP1
Sequence: MAKKSKQMRAALEKVDSTKAYSVEEAVALVKETNFAKFDASVEVAYNLNIDVRKADQQIRGAMVLPNGTGKTQRVLVFARGAKAEEAKAAGADFVGEDDLVAKINGGWLDFDVVIATPDMMAIVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGKITYRADKAGNVQALIGKVSFDADKLVENFKAFHDVMAKAKPATAKGTYMANVSITSTQGVGIKVDPNSL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: CYSD_SALCH
Sequence: MDQKRLTHLRQLEAESIHIIREVAAEFANPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYAFRDRTANAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWRNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMVDDDRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESHAQTLPEIIEEMLVSTTSERQGRMIDRDQAGSMELKKRQGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: Y480_MYCTU
Sequence: MRIALAQIRSGTDPAANLQLVGKYAGEAATAGAQLVVFPEATMCRLGVPLRQVAEPVDGPWANGVRRIATEAGITVIAGMFTPTGDGRVTNTLIAAGPGTPNQPDAHYHKIHLYDAFGFTESRTVAPGREPVVVVVDGVRVGLTVCYDIRFPALYTELARRGAQLIAVCASWGSGPGKLEQWTLLARARALDSMSYVAAAGQADPGDARTGVGASSAAPTGVGGSLVASPLGEVVVSAGTQPQLLVADIDVDNVAAARDRIAVLRNQTDFVQIDKAQSRG
What are the official names of this protein?
Hydrolase Rv0480c.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.
Protein: RL23_BACC0
Sequence: MRDPRDIIKRPVITERSMEMMAEKKYTFDVDVKSNKTEVKDALEAIFGVKVEKVNIMNYKPKAKRVGRHAGFTSRRRKAIVKLTADSKEIEIFQGV
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: GLND_VIBCH
Sequence: MPYQSPITFQEPQLTVESLKQQLESFTEYQKQEFFDHHPVTDLVLGRSEYMDLLLHRLWQFFGFDELVEVSLVAVGGYGRGELHPLSDIDLLVLSQQPLSEQVANKISQFLTLLWDLKLEIGHAVRTVEQCAEIGKADLTVATNLQEARLLCGCEETFHRLKMVIHSESFWPSEIFYQAKVREQKERHARYHDTTYNLEPDIKSTPGGLRDIHTLSWVARRHFGATSLYEMSRFGFLTDAEYRELVECQDFLWRVRFALHIELKRYDNRLTFAHQVQVARHLGYFGEGNRGIEMMMKEFFRTLRRVAELNKMLLKIFDKAILNNGEEAEAVIIDDDFQRRGNMIEARKPALFQARPETILDMFLHMASDSTIESVAPATMRQLRTARRRLNKFLHTLPAAREKFIELVRHPNALHKAFSQMHKLGVLAAYLPQWNQIVGQMQFDLFHVYTVDEHSIRLLKHIHLFSDANNHDRHPICCEIYPKIQKKELLILAAIFHDIGKGRGGDHSEIGADEAFDFCIEHGLSKPEAKLVAWLVKNHLLMSVTAQRRDIYDPDVIIEFAKKVRDEERLEYLVCLTVADICATNPELWNSWKRTLLAELFYSTQRALRRGLENPVDVRERIRHNQQMASALLRKEGFSSREIEVLWQRFKADYFLRHTHKQIAWHCTHLLRHEDSSKPLVLLSKKATRGGTEVFIYTKDQAALFATVVAELDRRNLNVHDAQIMASKDGYVLDTFMVLDQNGQAIEEDRHQALIRHLVHVLEDGRPTTQKARRIPRNLQHFKVKTQVDFLPTKSKKRTLMEFVALDTPGLLATVGATFAELNLDLHAAKITTIGERAEDLFILTNAQGTRLNEEEEQHLREKLIEHVAELAPSAQ
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: CP21A_BOVIN
Sequence: MVLAGLLLLLTLLAGAHLLWGRWKLRNLHLPPLVPGFLHLLQPNLPIHLLSLTQKLGPVYRLRLGLQEVVVLNSKRTIEEAMIRKWVDFAGRPQIPSYKLVSQRCQDISLGDYSLLWKAHKKLTRSALLLGTRSSMEPWVDQLTQEFCERMRVQAGAPVTIQKEFSLLTCSIICYLTFGNKEDTLVHAFHDCVQDLMKTWDHWSIQILDMVPFLRFFPNPGLWRLKQAIENRDHMVEKQLTRHKESMVAGQWRDMTDYMLQGVGRQRVEEGPGQLLEGHVHMSVVDLFIGGTETTASTLSWAVAFLLHHPEIQRRLQEELDRELGPGASCSRVTYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSIFGYDIPEGMVVIPNLQGAHLDETVWEQPHEFRPDRFLEPGANPSALAFGCGARVCLGESLARLELFVVLLRLLQAFTLLPPPVGALPSLQPDPYCGVNLKVQPFQVRLQPRGVEAGAWESASAQ
What is the function of this protein?
A cytochrome P450 monooxygenase that plays a major role in adrenal steroidogenesis.  Catalyzes the hydroxylation at C-21 of progesterone and 17alpha-hydroxyprogesterone to respectively form 11-deoxycorticosterone and 11-deoxycortisol, intermediate metabolites in the biosynthetic pathway of mineralocorticoids and glucocorticoids (PubMed:25855791, PubMed:22262854).  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase) (PubMed:25855791, PubMed:22262854).
What are the official names of this protein?
Steroid 21-hydroxylase, 21-OHase, Cytochrome P-450c21, Cytochrome P450 21, Cytochrome P450 XXI, Cytochrome P450-C21.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: CHRB1_CUPMC
Sequence: MNALPSSPETAWLLLVVSLPTSASTARMRFWRGIKALGATALRDGAYLLPNLPGLRAPLQTLATDAASEDGKVWMLSVQAADDQQEAEYRALFDRSTEYAEWMVELSSARSTLSDSDEAELLRVARRHGRGIDAIRKVDFFPNEASARAELQWRDFNAAIDILLSPGEPHGVAGNIPRRDPTQYQGRQWATRQHLWVDRVACAWLIRRFIDPHATFLWLEDVRQCPDDALGFDFDGATFTHIGDRVSFEVLLASFGLDEDKGLARLGQMIHVLDVGGTPVAEASGFEAVLAGARERLPNDDALLDEVGYVLDSLYTHFSSPRKR
What is the function of this protein?
Together with ChrA1, this protein reduces chromate accumulation and is essential for chromate resistance, possibly as a regulatory protein.
What are the official names of this protein?
Protein ChrB.
Protein: CHCH3_CAEEL
Sequence: MGASQSAEQEARPEVVRIDRNEIPEEYKTVGVSSDVVSRVNATRVAGNDGESDRLRQELAREREEKARLREDMAKLSQLQQRKTAGISAAPVSISGNDLEERKKIFDDTVERVQKQFFAYHRENVCQDNENEIVRCLQENPGRVLKCAPLTEAFEKCVGEFRQQVLKGN
What is the function of this protein?
Plays a role in maintaining mitochondrial morphology (PubMed:21248201).  May act as a component of the MICOS complex, a large protein complex of the mitochondria (By similarity).
What are the official names of this protein?
MICOS complex subunit MIC19, Coiled-coil-helix-coiled-coil-helix domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the MICOS complex subunit Mic19 family. Metazoan Mic19 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Lipid-anchor; Intermembrane side.
Protein: QUEC_METAC
Sequence: MKAITLLSSGLDSVAALAIAAESLEIEMAITFDYGQRAGQREIEYSRKVCEHYGIEHIVIKLDWLAGITNTSLVNRGEDVPALSFEDIDEAAPAAITEASAKAVWVPNRNGVMLNIAGSFAESRDCDYLVVGFNGEEAGTFPDNSMAYVEAMDNAFSYSTQNGVRVLAPLIELGKTEIVKKALEVKAPLEYSWSCYHGEETPCGGCESCVRRARAFKNTGTKDPLLERLGV
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, Archaeosine biosynthesis protein QueC, PreQ(0) synthase.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: PYRI_KORCO
Sequence: MKEELVVRRISDGTVIDHIPAGRALRVLKLLGITGERDGVVALVMNVPSKKLGKKDIVKIEGRELSKEEVDKISLIAPSATINIIRNFEVASKRRVELPRRVVGILRCLNPNCVTNAPREAVEPSFTLISESPLRMVCEYCGEYLREEDIIEQLSGV
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: UN13A_RAT
Sequence: MSLLCVGVKKAKFDGAQEKFNTYVTLKVQNVKSTTIAVRGSQPSWEQDFMFEINRLDLGLTVEVWNKGLIWDTMVGTVWIPLRTIRQSNEEGPGEWLTLDSQAIMADSEICGTKDPTFHRILLDAHFELPLDIPEEEARYWAKKLEQLNAMRDQDEYSFQDQQDKPLPVPSSQCCNWNYFGWGEQNDDPDSAVDDRDSDYRSETSNSIPPPYYTTSQPNASVHQYSVRPPPLGSRESYSDSMHSYEEFSEPRALSPTGSSRYASSGELSQGSSQLSEDFDPDEHSLQGSELDDERDRDSYHSCHSSVSYHKDSPRWDQDEEDLEDLEDLEDEELPEEEELEEEELEEEEELEEEELELEEEEEVPDDLASYTQQEDTTVAEPKEFKRISFPTAAPQKEDKVSAVPIEAPDVSKGIPKAATPEEKAAAECAQEAEPPKSEESFRSREAEEGQEGQDAMSRAKANWLRAFNKVRMQLQEARGEGEMSKSLWFKGGPGGGLIIIDSMPDIRKRKPIPLVSDLAMSLVQSRKAGITSALASSTLNNEELKNHVYKKTLQALIYPISCTTPHNFEVWTATTPTYCYECEGLLWGIARQGMRCTECGVKCHEKCQDLLNADCLQRAAEKSSKHGAEDRTQNIIMVLKDRMKIRERNKPEIFELIQEVFAVTKSAHTQQMKAVKQSVLDGTSKWSAKISITVVCAQGLQAKDKTGSSDPYVTVQVGKTKKRTKTIYGNLNPVWEENFHFECHNSSDRIKVRVLDEDDDIKSRVKQRFKRESDDFLGQTIIEVRTLSGEMDVWYNLDKRTDKSAVSGAIRLHISVEIKGEEKVAPYHVQYTCLHENLFHFVTDVQNNGVVKIPDAKGDDAWKVYYDETAQEIVDEFAMRYGVESIYQAMTHFACLSSKYMCPGVPAVMSTLLANINAYYAHTTASTNVSASDRFAASNFGKERFVKLLDQLHNSLRIDLSMYRNNFPASSPERLQDLKSTVDLLTSITFFRMKVQELQSPPRASQVVKDCVKACLNSTYEYIFNNCHELYGREYQTDPAKKGEVPPEEQGPSIKNLDFWSKLITLIVSIIEEDKNSYTPCLNQFPQELNVGKISAEVMWSLFAQDMKYAMEEHDKHRLCKSADYMNLHFKVKWLYNEYVAELPTFKDRVPEYPAWFEPFVIQWLDENEEVSRDFLHGALERDKKDGFQQTSEHALFSCSVVDVFSQLNQSFEIIKKLECPDPQIVGHYMRRFAKTISNVLLQYADIVSKDFASYCSKEKEKVPCILMNNTQQLRVQLEKMFEAMGGKELDAEASGTLKELQVKLNNVLDELSHVFATSFQPHIEECVRQMGDILSQVKGTGNVPASACSSVAQDADNVLQPIMDLLDSNLTLFAKICEKTVLKRVLKELWKLVMNTMERTIVLPPLTDQTMIGTLLRKHGKGLEKGRVKLPSHSDGTQMIFNAAKELGQLSKLKDHMVREEAKSLTPKQCAVVELALDTIKQYFHAGGVGLKKTFLEKSPDLQSLRYALSLYTQATDLLIKTFVQTQSAQVHGGKGTRFTLSEDVCPEMGSGVEDPVGEVSVHVELFTHPGTGEQKVTVKVVAANDLKWQTSGIFRPFIEVNIVGPQLSDKKRKFATKSKNNSWAPKYNESFQFSLSADAGPECYELQVCVKDYCFAREDRTVELAVLQLRELAQRGSAACWLPLGRRIHMDDTGLTVLRILSQRSNDEVAKEFVKLKSDTRSAEEGGAAPAP
What is the function of this protein?
Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway.  Involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of readily releasable vesicle pool (RRP).  Essential for synaptic vesicle maturation in most excitatory/glutamatergic but not inhibitory/GABA-mediated synapses.  Facilitates neuronal dense core vesicles fusion as well as controls the location and efficiency of their synaptic release (By similarity).  Also involved in secretory granule priming in insulin secretion.  Plays a role in dendrite formation by melanocytes (By similarity).
What are the official names of this protein?
Protein unc-13 homolog A, Munc13-1.
What is the protein family that this protein belongs to?
Belongs to the unc-13 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein. Presynaptic cell membrane; Peripheral membrane protein. Presynaptic active zone. Note=Translocated to the plasma membrane in response to phorbol ester binding.
Protein: BARH2_HUMAN
Sequence: MTMEGASGSSFGIDTILSSASSGSPGMMNGDFRPLGEARTADFRSQATPSPCSEIDTVGTAPSSPISVTMEPPEPHLVADATQHHHHLHHSQQPPPPAAAPTQSLQPLPQQQQPLPPQQPPPPPPQQLGSAASAPRTSTSSFLIKDILGDSKPLAACAPYSTSVSSPHHTPKQESNAVHESFRPKLEQEDSKTKLDKREDSQSDIKCHGTKEEGDREITSSRESPPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFYHPSLLGSMDSTTAAAAAAAMYSSMYRTPPAPHPQLQRPLVPRVLIHGLGPGGQPALNPLSSPIPGTPHPR
What is the function of this protein?
Potential regulator of neural basic helix-loop-helix genes.
What are the official names of this protein?
BarH-like 2 homeobox protein.
What is the protein family that this protein belongs to?
Belongs to the BAR homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NCAP_PIRYV
Sequence: MSVSVKRISTGTQVVAALPASEDPVEFPAEYFAKNPGKIPVFISTRLDLDKLRQYVYMGLTTGEVNVCHINSYLYRVLQNIEDEARDNWVSFRVTIAAKDTTVRLFDMLEVKEYAGLVPDGKENANLTQTVDEWLPMYILGLQRVGRATDERYRGDLYDHLCAQCKLKSPSFESLGNPADNNYASWINDSNFLKLVAAIDMFFHHFKKHEEAVIRFGTITSRFKDCAALSTMAHLVKVTGMPVEEVMTWVLNKPVEDEVCRMMTPGQEIDKADSYMPYLIDFGLSTKSPYSSVKNPCFHFWGQLTAVLVNSARARNARVPDDIPYQELTQAALLFAYATGRSSDLAQRFVLHNKEYIKAAPDASDNSEREESKEAPTTRDVVEWLAWWDDIGQVRTRDMEVFARRAVHGILDPREKSIGAYARGYFA
What is the function of this protein?
Encapsidates the genome in a ratio of one N per nine ribonucleotides, protecting it from nucleases.  The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication.  Replication is dependent on intracellular concentration of newly synthesized N, termed N(0), which corresponds to the protein not associated with RNA.  In contrast, when associated with RNA, it is termed N.  During replication, encapsidation by N(0) is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).
What are the official names of this protein?
Nucleoprotein, NP, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the vesiculovirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=The nucleocapsid is synthesized in the cytoplasm, and is subsequently transported via microtubules to the cell periphery.
Protein: CYSZ_ECOL6
Sequence: MVSSFTSAPRSGFYYFAQGWKLVLQPGIRRFVILPLLVNILLMGGAFWWLFTQLDVWIPTLMSYVPDWLQWLSYLLWPLAVISVLLVFGYFFSTIANWIAAPFNGLLAEQLEARLTGATPPDTGIFGIMKDVPRIMKREWQKFAWYLPRAIVLLILYFIPGIGQTVAPVLWFLFSAWMLAIQYCDYPFDNHKVPFKEMRTALRTRKITNMQFGALTSLFTMIPLLNLFIMPVAVCGATAMWVDCYRDKHAMWR
What is the function of this protein?
High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake.  Provides the sulfur source for the cysteine synthesis pathway.
What are the official names of this protein?
Sulfate transporter CysZ.
What is the protein family that this protein belongs to?
Belongs to the CysZ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL13_CHLCV
Sequence: MEKRKDTKTTIAKASDAQNKSWYVIDATGKTLGRLSSEVAKILRGKHKVTYTPHIAMGDGVIVINAEKVHLTGAKKGQKIYRYYTGYISGMREIPFENMLAKKPSYIIEHAIKGMMPKTRLGKRQLKSLRILKGDCYKTFEAQKPILLDV
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: NR0B1_PONPY
Sequence: MAGENHQWQGSILYNMLMSAKQTRAAPEAPETRLVDQCWGCSCGDEPGVGREGLLGGRNVALLYRCCFCGKDHPRQGSILYSMLTSAKQTYATPKAPEATLGPCWGCSCGSDPGVGRTGLPGGRPVALLYRCCFCGEDHPRQGSILYSLLTSAKQTHVAPAAPEARPGGAWWDRSYFAQKPGGREALPGGRATALLYRCCFCGEDHPQQGSTLYCMPTSTNQAQAAPEERPRAPWWDASSGALRPVALKNPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLELAQDRLQFETVEVSEPSMLQKILTTRRRETGGNEPLPVPTLQPHLAPPAEARKVPSASQVQAIKCFLSKCWSLNISTKEYAYLKGTVLFNRDVPGLQCVKYIQGLQWGTQQILSEHTRMTHQGPHDRFIELNSALFLLRFINANVIAELFFRPIIGTVSMDDMMLEMLCTKI
What is the function of this protein?
Orphan nuclear receptor.  Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis.  Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions.  May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity).
What are the official names of this protein?
Nuclear receptor subfamily 0 group B member 1, Nuclear receptor DAX-1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR0 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between the cytoplasm and nucleus. Homodimers exits in the cytoplasm and in the nucleus (By similarity).
Protein: RL22_MYCTO
Sequence: MTAATKATEYPSAVAKARFVRVSPRKARRVIDLVRGRSVSDALDILRWAPQAASGPVAKVIASAAANAQNNGGLDPATLVVATVYADQGPTAKRIRPRAQGRAFRIRRRTSHITVVVESRPAKDQRSAKSSRARRTEASKAASKVGATAPAKKAAAKAPAKKAPASSGVKKTPAKKAPAKKAPAKASETSAAKGGSD
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: DAPB_RUEPO
Sequence: MTHIPGIVITGASGRMGQMLVRTVTDSDKVRLVGALERPGHDWIGRDVGEAMGGQALGVAVTDDPLEAFAQAQAVIDFTAPAATLGFAALAAQARCVHVIGTTGMTAEQIAALEPAARHAVIVRAGNMSLGVNLLVQLTKKVAAALDEDFDIEVIEAHHHHKVDAPSGTALMLGEAAAEGRGVRLDDVADRARDGITGARTRGDIGFHAIRGGDIVGEHDVLFAAPGERIVLRHVASDRAVFARGALKAALWGQGKAPGHYDMVDVLGL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VE1_PCPVC
Sequence: MADDTGTDNEGTGCSGWFLVEAIVDKTTGEQVSDDEDETVEDSGLDMVDFIDDRPITHNSLEAQALLNEQEADAHYAAVQDLKRKYLGSPYVSPLGHIEQSVDCDISPRLDAIQLSRKPKKVKRRLFQSREITDSGYGYSEVETATQVERYGEPENGCGGGGDGREKEGEGQVHTEVHTESEIEQHTGTTRVLELLKCKDVRATLHGKFKECYGLSFKDLTREFKSDKTTCGDWVVAGFGVHHSVSEAFQKLIQPLSTYSHIQWLTNYKCMGMVLLVLLRFKVNKNRCTVARTLATLLNIPEDHMLIEPPKIQSSVAALYWFRTSISNASIVTGDTPEWIARQTIVEHGLADNQFKLTEMVQWAYDNDYCDESDIAFEYAQRADFDSNAKAFLNSNCQAKYVKDCATMCKHYKNAEMKKMSIKQWIKYRSNKIDETGNWKPIVQFLRHQGIEFISFLSKLKLWLHGTPKKNCIAIVGPPDTGKSAFCMSLIKFLGGTVISYVNSSSHFWLQPLCNAKVALLDDATQSCWGYMDTYMRNLLDGNPMSIDRKHKSLALIKCPPLLVTSNIDITTEERYKYLYSRVTLFKFPNPFPFDSNGNAVYELCDANWKCFFARLSASLDIQDSEDEDDGDTSQAFRCVPGTVVRTV
What is the function of this protein?
ATP-dependent DNA helicase required for initiation of viral DNA replication.  It forms a complex with the viral E2 protein.  The E1-E2 complex binds to the replication origin which contains binding sites for both proteins.  During the initial step, a dimer of E1 interacts with a dimer of protein E2 leading to a complex that binds the viral origin of replication with high specificity.  Then, a second dimer of E1 displaces the E2 dimer in an ATP-dependent manner to form the E1 tetramer.  Following this, two E1 monomers are added to each half of the site, which results in the formation of two E1 trimers on the viral ori.  Subsequently, two hexamers will be created.  The double hexamer acts as a bi-directional helicase machinery and unwinds the viral DNA and then recruits the host DNA polymerase to start replication.
What are the official names of this protein?
Replication protein E1, ATP-dependent helicase E1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E1 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: Y1637_HAEIN
Sequence: MFNRVQKEINQIINRGFDRTLRLAVTGLSRSGKTAFITSLINQLLSINQHSSQNLPLFEAARNGSILAVKRVSQQDLSVPRFDYESNLNDLSQNPPQWFQSTRGVSETRLAIRFQRQSGLLRHLKERGTLYLDIFDYPGEWLLDLPLLNLDFQQWSQEQIKVTTGVRAELAQNWLSMLQNLDLSAVANEDVLAKIAKSYTDYLHQCKAQGMQFIQPGRFVLPSDLEGAPALQFFPLIHLSGEHWQTLKKTAKSNSYFAVLTKRYNYYRNKIVKGFYENYFSTFDRQVILADCLTPLNHSQQAFLDMQMGLNQLFNNFHYGSRNFLHRLFSPQIDRLMFVATKADHITRDQIPNLVSLMRQIVQEGGRHVEFEGIDTEYTAIAAVRTTKQVIVNQQGKEIKAIQGVRSIDKQLITLYPGTVPSKLPKTEFWQKQPHFDFDSFEPQPLEQGESIPHLRMDAVLQFLLSDRFE
What are the official names of this protein?
Uncharacterized protein HI_1637.
What is the protein family that this protein belongs to?
To E.coli YcjX.
Protein: PANC_SHIF8
Sequence: MLIIETLPLLRQQIRRLRMEGKRVALVPTMGNLHNGHMKLVDEAKARADVVVVSIFVNPMQFDRPEDLARYPRTLQEDCEKLNKRKVDLVFAPSVKEIYPNGTETHTYVDVPGLSTMLEGASRPGHFRGVSTIVSKLFNLVQPDIACFGEKDFQQLALIRKMVADMGFDIEIVGVPIMRAKDGLALSSRNGYLTAEQRKIAPGLYKVLSSIADKLQAGERDLDEIITIAGQELNEKGFRADDIQIRDADTLLEVSETSKRAVILVAAWLGDARLIDNKMVELA
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2443_STAEQ
Sequence: MRYLKKVTIYISLLILVSGCGNGKETEIKQNFNKMLDMYPTKNLEDFYDKEGYRDEEFDKKDKGTWIVGSTMTIEPKGKYMESRGMFLYINRNTRTTKGYYYVRKTTDDSKGRLKDDEKRYPVKMEHNKIIPTKPIPNDKLKKEIENFKFFVQYGDFKNLKDYKDGDISYNPNVPSYSAKYQLSNNDYNVKQLRKRYDIPTNQAPKLLLKGDGDLKGSSIGSKSLEFTFIENKEENIFFSDGVQFTPSEDSES
What are the official names of this protein?
Uncharacterized lipoprotein SERP2443.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal tandem lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: RS4_SALPA
Sequence: MARYLGPKLKLSRREGTDLFLKSGVRAIDTKCKIEQAPGQHGARKPRLSDYGVQLREKQKVRRIYGVLERQFRNYYKEAARLKGNTGENLLALLEGRLDNVVYRMGFGATRAEARQLVSHKAIMVNGRVVNIASYQVSPNDVVSIREKAKKQSRVKAALELAEQREKPTWLEVDAGKMEGTYKRKPERSDLSADINEHLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: ATPL_SALPA
Sequence: MENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPDLIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.