PharMolix/UniProtQA huggingface dataset:
Protein: TVP23_YARLI
Sequence: MTLWQRLSESSHPVALVFFLAFRLGALFTYMFGLLFTDKFVLMFVLVVLLLAADFWNVKNIAGRLMVGLRWWNEASETGESVWVFETADPQRYINPIDSKVFWMMLYGAPVLWVCLAVLALLKFQFLSLILVFIAVSLTVTNAMAYSRCDKFGKANNIVGQVSGGLLSRAARGTFLGRFM
What is the function of this protein?
Golgi membrane protein involved in vesicular trafficking.
What are the official names of this protein?
Golgi apparatus membrane protein TVP23.
What is the protein family that this protein belongs to?
Belongs to the TVP23 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: IOLG_CORGB
Sequence: MSKSLRVGVVGAGAMGADHIDRINNRTSGAHISAIIEPDAARAAAAAENAPGAQAFTRIEDAIAADAVDAVLIAVPGQFHEPVLVPALEAGLPILCEKPLTPDSESSLRIVELEQKLDKPHIQVGFMRRFDPEYNNLRKLVESGEAGELLMLRGLHRNPSVGENYTQSMLITDSVVHEFDVIPWLAGSRVVSVEVKYPKTSSLAHSGLKEPILVIMELENGVLVDVEMNVNIQFGYQVATEAVFEKGLARIGQPSGMQRWRDGEFLINEHTDFTTRFATAYDRQIQSWVDAVHEGTLVAGPNAWDGYLVALSCEAGVKAFDGGVIPVDAAPRPDFYA
What is the function of this protein?
Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).
What are the official names of this protein?
Inositol 2-dehydrogenase, Myo-inositol 2-dehydrogenase, MI 2-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
Protein: RBSD_KLEP7
Sequence: MKKGTVLNADISAVISRLGHTDTLVVCDAGLPVPRSSTRIDMALTQGVPSFMQVLEVVTTEMQVEAAVIAEEIKTHNPQLHATLLTHLEQLQQHQGNTIEIRYTSHELFKKQTADSQAVIRSGECSPFANIILCAGVTF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH10_ORYLA
Sequence: MAFRKFLPLFDRVLVERLMAETVTKGGIMLPEKSQGKVLQATVVAVGPGSMNQKGEVQPMSVKVGEKVLLPQYGGTKVVLEDKDYFLFRDADILGKYVD
What is the function of this protein?
Co-chaperonin implicated in mitochondrial protein import and macromolecular assembly.  Together with Hsp60, facilitates the correct folding of imported proteins.  May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.  The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back-to-back double ring.  In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per ring, followed by the binding of ATP and association with 2 heptameric rings of the co-chaperonin Hsp10.  This leads to sequestration of the substrate protein in the inner cavity of Hsp60 where, for a certain period of time, it can fold undisturbed by other cell components.  Synchronous hydrolysis of ATP in all Hsp60 subunits results in the dissociation of the chaperonin rings and the release of ADP and the folded substrate protein.
What are the official names of this protein?
10 kDa heat shock protein, mitochondrial, Hsp10, 10 kDa chaperonin, Chaperonin 10, CPN10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: FMT_DECAR
Sequence: MKLIFAGTPEFAAQALQGIVNAGHEVALVLTQPDRPAGRGMALQPSAVKKVALTHGIEVFQPLTLKDAEAQARIAAVGAEIMVVAAYGLILPQVVLDMPRFGCINIHGSLLPRWRGAAPIQRALLAGDAETGVCIMQMEAGLDTGPVLLRGAFPIAATDTTATLHDRLAELGARLVVEALGKLPLPAEPQPADGVTYAQKIEKAEAMIDWSKSAAELDRHIRAFNPFPGAQALFRGQTVKLWQASPVAGRGETGAILAVDKNSIIIACGEGALAVTELQKAGGKRLPVQQFLAGHPLAVGDRFDIPA
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: LUXS_LACH4
Sequence: MAKVESFTLDHTKVKAPYVRLITEETGKKGDVISNYDLRLVQPNTNAIPTAGLHTIEHLLAGLLRDRLDGVIDCSPFGCRTGFHLITWGKHSTTEVAKALKGSLEAIANDIEWKDVQGTDKYSCGNYRDHSLFSAKEWSKEILSQGISDQPFERHVI
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: H8A12_CYRHA
Sequence: MVNMKASMFLTFAGLVLLFVVCYASESEEKEFPKEMLSSIFAVDKDFKQEERDCAGYMRECKEKLCCSGYVCSSRWKWCVLPAPWRR
What is the function of this protein?
Ion channel inhibitor.
What are the official names of this protein?
U3-theraphotoxin-Hhn1a 12, U3-TRTX-Hhn1a, Hainantoxin-VIII.12, HNTX-VIII.12, Peptide F4-27.90.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 51 (Hntx-8) subfamily. Hntx-8 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: VME1_CVBEN
Sequence: MSSVTTPAPVYTWTADEAIKFLKEWNFSLGIILLFITVILQFGYTSRSMFVYVIKMVILWLMWPLTIILTIFNCVYALNNVYLGFSIVFTIVAIIMWIVYFVNSIRLFIRTGSWWSFNPETNNLMCIDMKGRMYVRPIIEDYHTLTVTIIRGHLYMQGIKLGTGYSLSDLPAYVTVAKVSHLLTYKRGFLDKIGDTSGFAVYVKSKVGNYRLPSTQKGSGLDTALLRNNI
What is the function of this protein?
Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.
What are the official names of this protein?
Membrane protein, M protein, E1 glycoprotein, Matrix glycoprotein, Membrane glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the betacoronaviruses M protein family.
What are the subcellular locations of this protein?
Virion membrane; Multi-pass membrane protein. Host Golgi apparatus membrane; Multi-pass membrane protein. Note=Largely embedded in the lipid bilayer.
Protein: SECA_POLSJ
Sequence: MASNILTQIFGSRNDRLLKTYRKIVDRINALETQYEQLGDDELRAKTQEFKNRVAAGEALDAILPEAFAVVREGSKRVMKMRHFDVQMLGGISLHNGKISEMRTGEGKTLTATLPVYLNALTGKGVHVVTVNDYLASRDARWMGKLYNFLGLTVGINLPNMSREEKQAAYNADITYGTNNEYGFDYLRDNMVYEVGDRVQRGLNYAIVDEVDSILIDEARTPLIISGQAEDHTEMYLAMNKVVPLLTRQEGEADPRTGEGVTKPGDFTIDEKTRQVFLTEQGHESAERILFNLGLIAESATLYDPANISLMHHLYAALRANLLYHRDQHYVVQDGEVVIVDEFTGRLMSGRRWSDGLHQAVEAKEGVQIQAENQTLASITFQNYFRLYGKLAGMTGTADTEAYEFQEIYGLETTVIPPNRVSRRDDQLDRVYKTTREKYEAAIKDIRECYERGQPVLVGTTSIENSEIIDQLLEKEKLPHQVLNAKQHAREADIVAQAGRLKVITIATNMAGRGTDIVLGGNLEKLIEAVEADESMDTAAKEAEIARLRARWSEEHEQVKALGGLRIIATERHESRRIDNQLRGRSGRQGDPGSSRFYLSLDDPLMRIFAGDRVKAIMERLKMPDGEAIEAGIVTRSIESAQRKVEARNFDIRKQLLEYDDVANDQRKVIYQQRNDIMDAGSLQAQIESLREGCFTDLTRQYVPAESVEEQWDIAGLEKVLLEEWQISLPLAGELESATAITDEDILEKVIAAANVAFADKVEKIGQENFTQFERLVLLQSIDTHWREHLSALDYLRQGIHLRGYAQKQPKQEYKREAFELFGQLLDSVKNEVTKVLMTVKIQSGEQLEQAAEEMENRAESISNVTYTAPTETGEAETRVDEDTLRRVSLASGIAVPRVGRNDPCPCGSGKKYKLCHGRLN
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: DNAJ_MARMS
Sequence: MSKRDYYDVLGVAKDADKKDIKKAYRSLANKYHPDKNPDNPEALDKFKELAEAYEILSSDDKRAAYDRFGHDGVNGQAGGYGGAGAGGFSDIFGDVFGDIFGGGGGGQSRTRRGSDLRYTLELDLEQAVWGCEEKIRIPTLVNCKTCDGSGAKKGSTPKTCGTCGGAGQVRMSQGFFSVQQTCPECHGAGQVISDPCRDCHGQGRVQEYKTLNVKIPAGVDTGDRIRLSGEGEAGTHGGPAGDLFVQVSVKPHSIFERDGANLYCEVPISFTTAALGGEIDVPTLDGRVRLKVTAECQSGKLFRLRNKGVKPVRGGPVGDLICKVVVETPVNLTSRQKELFTELAESMGEGTDHSPKQKSWFDGVKRFFDDIKK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMP1_CHICK
Sequence: GRKSDCFRKSGFCAFLKCPSLTLISGKCSRFYLCCKRIR
What is the function of this protein?
Bactericidal activity; inhibits S. aureus and E. coli.
What are the official names of this protein?
Antimicrobial peptide CHP1, Chicken heterophil peptide 1.
Protein: NDHI_RATCO
Sequence: MFPMVTEFMNYGQQTVRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSIIDDYTIRTILNLPEIKT
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: LIS11_PODAN
Sequence: MNTNILTTRQAEELHKAIIAYLTANNLSNTASALRTELNLGEDVFDPATAKKYEGLLEKKWTSVVRLQKKIMDLESRNSTLQSELANSTPTSRQNKDPVAWLPKSPARHTLQSHRNPITCVAFHPVFSSLASGSEDQTIKIWDWELGELERTIKGHTKAVLDVDFGGPRGNTLLASCSSDLTIKLWDPSDDYKNIRTLPGHDHSVSAVRFIPSGVAGGTGNLLVSASRDKTLRIWDVSTGYCVKTLRGHAEWVRDVCPSIDGRFILSTSDDYTGRLWDVSIPNPEPKTTLIGHEHVVLCCAIAPAAAYPHLAAMAGIKKPPATSAVEFMATGSRDKTIRLWDARGTCIKILVGHDNWVRGLVFHPGGQYLLSVADDYTLRCWDLTQEGRCVKTIGDAHGHFVQCIRWAPSIVKDVPAVNGEGANGESNGTPRKAAGAAGAGGEAQIRCVIATGSVDLNVRIFAN
What is the function of this protein?
Positively regulates the activity of the minus-end directed microtubule motor protein dynein.  May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end.  Required for nuclear migration during vegetative growth as well as development.  Required for retrograde early endosome (EE) transport from the hyphal tip.  Required for localization of dynein to the mitotic spindle poles.  Recruits additional proteins to the dynein complex at SPBs.
What are the official names of this protein?
Nuclear distribution protein PAC1-1, Lissencephaly-1 homolog 1, LIS-1 1, nudF homolog 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LIS1/nudF family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes to the plus ends of microtubules at the hyphal tip and the mitotic spindle poles.
Protein: RECR_GEOTN
Sequence: MHYPEPISKLIDSFMKLPGIGPKTAARLAFHVLAMKEDTVLEFAKALVDVKRHIHYCTICGHITDTDPCYICKDERRDRTMICVVQDPKDVIAMEKMKEYNGLYHVLHGAISPMEGIGPEDIKIAELLARLQDETIQEVILATDPNIEGEATAMYLSRLLKPTGIKITRIAHGLPVGGDLEYADEVTLSKALEGRREL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: THIE_LATSS
Sequence: MTNIAQEILQTYLVAGTQDTGRENFLPILDQALQAGITCFQFRDKGPNSLPTDAMRSDYAKKAQALCRTYHVPFIIDDRLELALDLQADGLHVGQSDQPWPKIEVAKQHGLITGLSCHTAQEILSSHQQPALDYIGVGPIFPTNSKEDAKTPLGLAQLKAFTQLSQLPVVAIGGISLKNCQQVAETGVAGAAVISAITQAKNIPQAIQLLNQPWQSSEGNNHES
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: SLIK5_MOUSE
Sequence: MHVCCPPVTLEQDLHRKMHSWMLQTLAFAVTSLVLSCAETIDYYGEICDNACPCEEKDGILTVSCENRGIISLSEISPPRFPIYHLLLSGNLLSRLYPNEFVNYTGASILHLGSNVIQDIETGAFHGLRGLRRLHLNNNKLELLRDDTFLGLENLEYLQVDYNYISVIEPNAFGKLHMLQVLILNDNLLSGLPNNLFRFVPLTHLDLRGNRLKLLPYVGLLQHMDKVVELQLEENPWNCSCELISLKDWLDSISYSALVGDVVCETPFRLHGRDLDEVSKQELCPRKLISDYEMRPQTPLSTTGYLHTTPASVNSVATSSSAVYKPPLKPPKGTRQPNKPRVRPTSRQPSKDLGYSNYGPSIAYQTKSPVPLECPTACTCNLQISDLGLNVNCQERKIESIAELQPKPYNPKKMYLTENYITVVRRTDFLEATGLDLLHLGNNRISMIQDRAFGDLGNLRRLYLNGNRIERLSPELFYGLQSLQYLFLQYNLIREIQAGTFDPVPNLQLLFLNNNQLQAMPSGVFSGLTLLRLNLRGNSFTSLPVSGVLDQLTSLIQIDLHDNPWDCTCDVVGMKLWIEQLKVGVLVDEVICKAPKKFAETYMRSIKSELLCPDYSDVVVSTPTPSSIQVPSRTNAATPAVRLNSTGTPAGLGAGTGASSVPLSVLILSLLLVFIMSVFVAAGLFVLVMKRRKKNQSDHTSTNNSDVSSFNMQYSVYGGGGGGGGGHPHAHVHHRGPALPKVKTPAGHVYEYIPHPLGHMCKNPIYRSREGNSVEDYKDLHELKVTYSSNHHLQQQPPPPPQQPQQQPPPQMQMQPGEEERRESHHLRSPAYSVSTIEPREDLLSPVQDADRFYRGILEPDKHCSTTPAGSSLPEYPKFPCSPAAYTFSPNYDLRRPHQYLHPGAGESRLREPVLYSPPGAVFVEPNRNEYLELKAKLNVEPDYLEVLEKQTTFSQF
What is the function of this protein?
Suppresses neurite outgrowth.
What are the official names of this protein?
SLIT and NTRK-like protein 5.
What is the protein family that this protein belongs to?
Belongs to the SLITRK family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: GCSPB_STAAT
Sequence: MTSKSSPLIFERSREGRYAYSLPKSDIKTNSVESLLDDKFIRKNKAEFPEVAELDLVRHYTELSNKNFGVDNGFYPLGSCTMKYNPKINEKVARIPGFSESHPLQDEDQVQGSLEIIYSLQEELKEITGMDEVTLQPAAGAHGEWTALMIFKAYHENNGEGHRDEVIVPDSAHGTNPASASFAGFKSVTVKSNERGEVDIDDLKRVVNENTAAIMLTNPNTLGIFEKNIMEIREIVHNAGGLLYYDGANLNAIMDKVRPGDMGFDAVHLNLHKTFTGPHGGGGPGSGPVGVVKELASYLPKPMVIKDGDKFKYDNDIKNSIGRVKPFYGNFGIYLRAYTYIRTMGATGLKEVSEAAVLNANYIKARLSKHFEIPYKQYCKHEFVLSGVRQKEFGVRTLDMAKRLLDFGVHPPTIYFPLNVEEGMMIEPTETESKETLDYFIDTLISIAEEAKNDPDKVLEAPHTTVIDRLDEATAARKPILKFENLKQEK
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 2, Glycine cleavage system P-protein subunit 2, Glycine decarboxylase subunit 2, Glycine dehydrogenase (aminomethyl-transferring) subunit 2.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. C-terminal subunit subfamily.
Protein: PDAD2_METAC
Sequence: MIPRKAFLTKGTGVHKDRLASFELALRDAKIEKYNLVSVSSILPPNCKLVTREEGLSELKPGAIVHCVLARNDTNEPHRLMASAIGTAVPVNEDNYGYISEHHSFGEEEIIAGEYAEDLAATMLATTLGIEFNAEMAWHEREQVYKASGHIFDTFHICQTAAGDKNGKWTTVVAAMVFVTSKC
What are the official names of this protein?
Pyruvoyl-dependent arginine decarboxylase 2, PvlArgDC 2.
What is the protein family that this protein belongs to?
Belongs to the PdaD family.
Protein: RNY_CHLTE
Sequence: MGIVINLFLIIAASIVFFVVGFYIGRFFLERIGTTKVLEAEERAVQVIQEAQKEANDYKELKVNEVNQEWKKRKREFDSEVTIKNNKFAQLQKQIRQKEVTLANQMRDIKETEKKLQEQREELKHQTQNVQNRSAELEKTILEQNQRLESISNLTAEEARQMLIDNMIAKAREEAAETVHQIHEEATQKADRIAEKIMLTAIQRISFEQATESALSVVHIQSDELKGRIIGREGRNIKAFENATGVDIIVDDTPEVVILSCFDPLRREMAKLTLQKLLVDGIIHPVAIEKAYQDAKKEIEDVIMSSGEEAISSLQIPDMPAEIVNLIGKMRFHTVYGQNLLQHSREVAMLAGLMAAELKLDAKQAKRAGLLHDIGLVLPETEMPHALAGMEFLKKFNMSPVVLNAIGAHHGEVEKASPIADLVDAANIVSLSRPGARGAVTAEGNVKRLESLEEIARTFPGVIKTYALQAGREIRVIVEGDNVSDSQADVLAHDIASKIESEAQYPGQIKVTILREKRSVAFAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: NCPP_ALIFM
Sequence: MKVIIASQNPAKIAAVESAFNLAFPNDTFSFEGVSVKSGVPDQPMSCEETKQGAINRVNNAKIKLPNCDYYVGLEAGIEGNSTFAWMIIDNGLTVGESRSSSLPLPPQVIDEVKKGKELGDVMDEQFNTDNIKQKGGAIGLLTNNLLTRTSVYQQALILALIPFLHPTRF
What is the function of this protein?
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives.  Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine/xanthosine triphosphatase, ITPase/XTPase, Non-canonical purine NTP phosphatase, Non-standard purine NTP phosphatase, Nucleoside-triphosphate phosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the YjjX NTPase family.
Protein: NUOC_CITBB
Sequence: MAENNRAVVKLKERFANALLDCTEYRGEVTVTVKKENILEVLKCLRDDLRYNFLTDVTAVDYLGQDPRFMVVYHLMSIPNKDRIRVKAPLTEADCSIDSATALWNSADWVEREAYDMFGIDFKNHPNLVRILMTDDWVGHPLRKDYPLQGPDREPYKGRLS
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CP107_PRIM1
Sequence: MKKVTVDDFSSPENMHDVIGFYKKLTEHQEPLIRLDDYYGLGPAWVALRHDDVVTILKNPRFLKDVRKFTPLQDKKDSIDDSTSASKLFEWMMNMPNMLTVDPPDHTRLRRLASKAFTPRMIENLRPRIQQITNELLDSVEGKRNMDLVADFSFPLPIIVISEMLGIPPLDQKRFRDWTDKLIKAAMDPSQGAVVMETLKEFIDYIKKMLVEKRNHPDDDVMSALLQAHEQEDKLSENELLSTIWLLITAGHETTAHLISNGVLALLKHPEQMRLLRDNPSLLPSAVEELLRYAGPVMIGGRFAGEDIIMHGKMIPKGEMVLFSLVAANIDSQKFSYPEGLDITREENEHLTFGKGIHHCLGAPLARMEAHIAFGTLLQRFPDLRLAIESEQLVYNNSTLRSLKSLPVIF
What is the function of this protein?
Cytochrome P450 whose physiological substrate is unknown.  In vitro, is able to catalyze the selective hydroxylation of mevastatin to pravastatin, the widely used therapeutic agent for hypercholesterolemia.
What are the official names of this protein?
Cytochrome P450 CYP107DY1, Mevastatin hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: CP1A1_LIMLI
Sequence: MMLMMLPFIGSVSVSESLVAMTTVCLVYLILKFFQTEIPEGLRRLPGPKPLPIIGNVLEMGSRPYLSLTAMSKRYGNVFQIQIGMRPVVVLSGSETVRQALIKQGDDFAGRPDLYSFRFINEGKSLAFSTDKAGIWRARRKLAYSALRSFATLEGTTPEYSCVLEEHVCKEGEYLIKQLNTAMTADGSFDPFRHIVVSVANVICGMCFGRRYDHDDQELVGLVTLSDEFGRVVGSGNPADFIPILQYLPSATMKNFLRINGRFTEFVQKIVTEHYTTFDKDNIRDITDSLIDHCEDRKLDENSNVQMSDEKIVGIVNDLFGAGFDTVSTALSWSVMYLVAHPEIQERLYQEIEDKVGLDRMPLLSDKPNLPFLEAFILEILRHSSFLPFTIPHCTTKDTSLNGYFIPKDTCVFINQWQINHDPEMWKDPSSFNPDRFLSADGSEVNKLDGEKVMAFGMGKRRCIGEVIARNEVYLFLAILIQKLHFLPIPGEKLDMTPEYGLTMKHKRCHLKATMRARNEH
What is the function of this protein?
Cytochromes P450 are a group of heme-thiolate monooxygenases.  They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
What are the official names of this protein?
Cytochrome P450 1A1, CYPIA1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: DNJH_ATRNU
Sequence: MFGRAPKKSDSTRYYEILGVPKDASPEDLKKAYKKAAIKNHPDKGGDPEKFKELAHAYEVLSDPEKREIYDQYGEDALKEGMGGGGGMHDPFDIFQSFFGGSPFGGVGSSRGRRQRRGEDVVHPLKVSLEDLFTGTTKKLSLSRNVICSKCTGKGSKSGASMKCSGCQGTGMKVSIRHLGPSMIQQMQHPCNECKGTGETINDKDRCPQCKGEKVVQEKKVLEVVVEKGMQHGQKITFPGEADEAPDTVTGDIVFVLQQKEHPKFKRKGEDLFYEHTLSLTEALCGFRFVLTHLDGRQLLIKSNLGEVVKPDQFKAIEDEGMPIYQRPFMKGKMYIHFTVEFPDSLNPDQVKSLEAILPPKPSMSLTYMELDECEETTLHNVNIEEEMKRKQTQAQQEAYDEDDEPAGGQRVQCAQQ
What is the function of this protein?
Plays a continuous role in plant development probably in the structural organization of compartments.
What are the official names of this protein?
DnaJ protein homolog ANJ1.
What are the subcellular locations of this protein?
Membrane; Lipid-anchor.
Protein: NIT1_SYNYG
Sequence: MKPYLAAALQMTSRPNLTENLQEAEELIDLAVRQGAELVGLPENFAFLGNETEKLEQATAIATATEKFLQTMAQRFQVTILAGGFPFPVAGEAGKAYNTATLIAPNGQELARYHKVHLFDVNVPDGNTYWESATVMAGQKYPPVYHSDSFGNLGLSICYDVRFPELYRYLSRQGADVLFVPAAFTAYTGKDHWQVLLQARAIENTCYVIAPAQTGCHYERRHTHGHAMIIDPWGVILADAGEKPGLAIAEINPDRLKQVRQQMPSLQHRVFV
What is the function of this protein?
Hydrolyzes deaminated glutathione (dGSH, 2-oxoglutaramate) to alpha-ketoglutarate (alpha-KG) and cysteinylglycine (specific activity 7. 77 umol/min/mg), hydrolyzes alpha-ketoglutaramate (a-KGM, specific activity 2. 13 umol/min/mg), has no activity on glutathione or L-glutamine.  May function as a metabolite repair enzyme.
What are the official names of this protein?
Deaminated glutathione amidase, dGSH amidase, Nitrilase homolog 1, syNit1.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.
Protein: FTHS2_STRPG
Sequence: MVLSDIEIANSVTMEPISKVADQLGIDKEALCLYGKYKAKIDARQLVALKDKPDGKLILVTAISPTPAGEGKTTTSVGLVDALSAIGKKAVIALREPSLGPVFGVKGGAAGGGHAQVVPMEDINLHFTGDFHAIGVANNLLAALIDNHIHHGNSLGIDSRRITWKRVVDMNDRQLRHIVDGLQGKVNGVPREDGYDITVASEIMAILCLSENISDLKARLEKIIIGYNFQGEPVTAKDLKAGGALAALLKDAIHPNLVQTLEHTPALIHGGPFANIAHGCNSVLATKLALKYGDYAVTEAGFGADLGAEKFIDIKCRMSGLRPAAVVLVATIRALKMHGGVPKADLATENVQAVVDGLPNLDKHLANIQDVYGLPVVVAINKFPLDTDAELQAVYDACDKRGVDVVISDVWANGGAGGRELAEKVVALAEQDNQFRFVYEEDDSIETKLTKIVTKVYGGKGIKLTPTAKRELAELERLGFGNYPICMAKTQYSFSDDAKKLGAPTDFIVTISNLKVSAGAGFIVALTGAIMTMPGLPKVPASETIDIDEEGNITGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase 2, Formyltetrahydrofolate synthetase 2, FHS 2, FTHFS 2.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: RL14_ACTP7
Sequence: MIQEQTMLDVADNSGARSVMCIKVLGGSHRRYAAIGDIIKVTVKEAIPRGKVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVILNNNTEQPIGTRIFGPVTRELRSEKFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.