PharMolix/UniProtQA huggingface dataset:
Protein: TGT_PROM9
Sequence: MFQFEITSNCSNTDARTGIFHTPNGQVNTPRFMPVGTLGTVKGISSKQLTSTGSEMILSNTFHLHLQPGEKLVKESGGIHKFMNWPKPILTDSGGYQVFSLAKLNNISDKGVEFKNPRDGSHVFLSPEKVMQIQMDLGSDVAMAFDHCPPHTANENDIEDSLLRTHSWLQKCVETHQKSNQALFGIIQGGKYPRLREYSAKFTSSFDLPGIAVGGVSVGEAVEEIHSVINYIPKFLPINKPRYLMGIGSLREISLAVAKGFDIFDCVLPTRLGRHGTAFFNDQRLNLRNARFKNDFSPIDKTCKCETCKSYSRAYLHHLIRNDEILGLTLISLHNIAHLIRFTNAISNAIKDNCFTIDFAPWKTASIAHHTW
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: TGT_KLEP7
Sequence: MKFELDTTDGRARRGRLVFERGVVETPAFMPVGTYGTVKGMTPEEVEATGAQIILGNTFHLWLRPGQEIMKLHGDLHDFMQWKGPILTDSGGFQVFSLGDIRKITEQGVHFRNPINGDPIFLDPEKSMEIQYDLGSDIVMIFDECTPYPADWDYAKRSMEMSLRWAKRSRDRFDSLGNKNALFGIIQGSVYEDLRDISVKGLVEIGFDGYAVGGLAVGEPKEDMHRILEHVCPQIPADKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGHLFVTDGVVKIRNAKHKSDTAPLDAECDCYTCRNYSRAYLHHLDRCNEILGARLNTIHNLRYYQRLMAGLRKAIEEGKLESFVTDFYQRQGRTVPPLNVD
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: YSW1_YEAST
Sequence: MSSLADTVEGSEAKRGRFSNNALTSDTGILQKNSTLRNWFLKPTADLKNSCEDRVEDDVNDVYLNDKNSQKSVEERKLGRKVRSFFKQTNSNKDESVLEDEDDALVWKKTSNKCAKKENSHDIQKGSFTKKIRNSIFKSANDVKEFRNENNLLLPVELSSDDENESHFTDANSHVMQSKSPEKIPSKDQCLTKGAKNKGLKKEYEKSFEEYSDDSDDEFSPATPPENVLEGPYKFVFQTPNTFTSQPNITVENDFHKGGRHVIDYLNKKLATMNIDIDLTSGGKQNVSWEEELDQLSDHVIESITNHISKGRMHAQEKQDELEKLKLENLNLSTLKQENLQHKQEINSLKDNLESISKKNNDLILEMNKLKKKSTNNKTNEYISTDENENEEITKSNMGPGILELNVNETSKKLQQSTFKPSKYLPRETRNNENRLKHLEKRIFGLEKSLEKKKKQVRADSVRLDLNRYTIDQFLTLLKSLSEVLQFHNVYGNDLKENDDNIIKIETCCSALNMKNCFEDSSFRLQENSFKRQLGPLFANINFSLIDQLTMNFRFYERSANFQKETIGGLRMMLQDKDNYIKTLMQHLKKKESTKLIKDSKNGASTLTS
What are the official names of this protein?
Spore-specific protein YSW1.
Protein: SYY_PSEA8
Sequence: MSVPTHQQDLIALLEERGFVHQCTDRDGLAAHLAAGPATAYLGFDATADSLHVGHLQGLMLMRWLQKAGHRPLLLIGGATTRIGDPSFRDSSRPILTEAQIQANIDGIARVFSRYVELHDDSLVNNAEWLDGVGYLEFLDRVGRHFSINRLLTFDAIRQRLDREHSLSFLEFGYTLLQAYDFVELSRRRGCTLQLGGADQWANIINGVELSRRQGGAQLFGLTMPLLATSDGRKMGKSAQGAVWLNAERLAPFDFWQFWRNCDDRDVGRFLALFSELPMDEVRRLGALQGAELNEAKVVLANAATALAHGEHAARSAADAARGVFADGTRDSGLPVMKLSRARLAQGLSLTDLLLEHAIQPSRSAVRRLAAGGGLRLDGTPVSDPDAPLAGEVDGLRLSLGKKQHLHLRLED
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFB_STAAS
Sequence: MLISNEWLKEYVTIDDSVSNLAERITRTGIEVDDLIDYTKDIKNLVVGFVKSKDKHPDADKLNVCQVDIGEDEPVQIVCGAPNVDAGQYVIVAKVGGRLPGGIKIKRAKLRGERSEGMICSLQEIGISSNYIPKSFESGIYVFSESQVPGTDALQALYLDDQVMEFDLTPNRADALSMIGTAYEVAALYNTKMTKPDTTSNELELSANDELTVTIENEDKVPYYSARVVHDVTIEPSPIWMQARLIKAGIRPINNVVDISNYVLLEYGQPLHMFDQDAIGSQQIVVRQANEGEKMTTLDDTERELLTSDIVITNGQTPIALAGVMGGDFSEVKEQTSNIVIEGAIFDPVSIRHTSRRLNLRSESSSRFEKGIATEFVDEAVDRACYLLQTYANGKVLKDRVSSGELGAFITPIDITADKINRTIGFDLSQNDIVTIFNQLGFDTEINDDVITVLVPSRRKDITIKEDLIEEVARIYGYDDIPSTLPVFDKVTSGQLTDRQYKTRMVKEVLEGAGLDQAITYSLVSKEDATAFSMQQRQTIDLLMPMSEAHASLRQSLLPHLIEAASYNVARKNKDVKLFEIGNVFFANGEGELPDQVEYLSGILTGDYVVNQWQGKKETVDFYLAKGVVDRVSEKLNLEFSYRRADIDGLHPGRTAEILLENKVVGFIGELHPTLAADNDLKRTYVFELNFDALMSVSVGYINYQPIPRFPGMSRDIALEVDQNIPAADLLSTIHAHGGNILKDTLVFDVYQGEHLEKGKKSIAIRLNYLDTEETLTDERVSKVQAEIEAALIEQGAVIR
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLA_PROTO
Sequence: DCPSGWSSFKQYCYKPFKQLKTWEDAERFCLEQVKGAHLV
What is the function of this protein?
Platelet antagonist that specifically and reversibly binds to a site on platelet glycoprotein Ibalpha (GP1BA) close to or identical with the site for vWF binding.  It inhibits the binding of vWF to platelets and vWF-dependent shear-induced platelet aggregation.
What are the official names of this protein?
Snaclec tokaracetin subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: FAXC_OXYMI
Sequence: MAPQLLLCLILTFLWSLPEAESNVFLKSKVANRFLQRTKRANSLFEEFRSGNIERECIEERCSKEEAREVFEDDEKTETFWNVYVDGDQCSSNPCHYRGTCKDGIGSYTCTCLFGYEGKNCERVLYKSCRVDNGNCWHFCKPVQNDIQCSCAEGYLLGEDGHSCVAGGNFSCGRNIKTRNKREASLPDFVQSQNATLLKKSDNPSPDIRIVNGMDCKLGECPWQAVLVDEKEGVFCGGTILSPIYVLTAAHCINQTEKISVVVGEIDKSRVETGHLLSVDKIYVHKKFVPPKKGYKFYEKFDLVSYDYDIAIIQMKTPIQFSENVVPACLPTADFANQVLMKQDFGIISGFGRIFEKGPKSNTLKVLKVPYVDRHTCMVSSESPITPTMFCAGYDTLPRDACQGDSGGPHITAYRDTHFITGIVSWGEGCAKKGKYGIYTKVSKFILWIKRIMRQKLPSTESSTGRL
What is the function of this protein?
Snake prothrombin activator that attacks the hemostatic system of prey.  This catalytic subunit is functionally similar to blood coagulation factor Xa.  It requires a non-catalytic subunit present in the venom, which is similar to coagulation factor Va, to be fully active (By similarity).
What are the official names of this protein?
Venom prothrombin activator omicarin-C catalytic subunit, vPA, Venom coagulation factor Xa-like protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CGA1_ORYSJ
Sequence: MSTIYMSQLPATLPLMEGDQDQGLYPAFHRAKDPPILFPFMIDSAVEHQGQIYGDQGLRRQQVLGESNQQFNDHMMMGGSDVFLTPSPFRPTIQSIGSDMIQRSSYDPYDIESNNKQHANGSTSKWMSTPPMKMRIIRKGAATDPEGGAVRKPRRRAQAHQDESQQQLQQALGVVRVCSDCNTTKTPLWRSGPCGPKSLCNACGIRQRKARRAMAAAANGGAAVAPAKSVAAAPVNNKPAAKKEKRAADVDRSLPFKKRCKMVDHVAAAVAATKPTAAGEVVAAAPKDQDHVIVVGGENAAATSMPAQNPISKAAATAAAAAASPAFFHGLPRDEITDAAMLLMTLSCGLVHS
What is the function of this protein?
Transcriptional regulator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters (By similarity).  Influences the expression of nuclear encoded chloroplast-targeted genes.  Regulates chloroplast development and promotes chlorophyll accumulation.  Modulates plant architecture (e. g.  height, length and width of leaf blades, and flowering tillers production) and represses tillering, probably by modulating number of cells.  Promotes senescence.  Involved in grain filling, panicle development and starch production (PubMed:23548780).
What are the official names of this protein?
Protein CYTOKININ-RESPONSIVE GATA TRANSCRIPTION FACTOR 1, OsCGA1.
What is the protein family that this protein belongs to?
Belongs to the type IV zinc-finger family. Class B subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SUCC_SHEWM
Sequence: MNLHEYQAKSLFAEYGLPVSEGFACDTAQEAVEAAGHIGGDMWVVKCQVHAGGRGKAGGVKVTGDKNEIRAFAEHWLGKNLVTYQTDEKGQPVAKILVESCTDIANELYLGAVVDRASRRVVFMASTEGGVEIETVAEETPELIHKAIIDPLAGPQPYQARDLGFKLGLNPTQLKQFTKVFMGLAKMFEDHDFALLEINPLVITDEGNIHCLDGKIGIDGNALYRQPKIREMHDPSQDDAREAHAAKFELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAEAFKIILSDDNVKAVLVNIFGGIVRCDMIAEGIIGAVKEVGVTVPVVVRLEGTNADLGREVLANSDLDIIAATSLTDAAEQVVKAAEGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: EXG_CANOL
Sequence: MLLTFAPIFLLISSIVAAPTLQLQRKGLEWDYQNDKIRGVNLGGWFVLEPYITPSLFSVWSNGEDDLNTPVDEYHYTQKLGKETALSRLEAHWSSWYTEADFAQMKYLGINAVRIPIGYWAFQLLDNDPYVQGQVKYLDQALEWCRNNGLYAWVDLHGAPGSQNGFDNSGLRDSYKFQDDDDVKVTLEVLKTIGAKYGGSDYEDVVIGIELLNEPLGPVLDMDGLRQFYQDGYSEIRNNDGVESYNAIIIHDAFQQTDHYWDNFMQVSGGYWNVVVDHHHYQVFDQAALELLIEDHIKTACNWGTTHKDEAHWNIVGEWSSALTDCAKWLNGVGHGARWSGNYDNCPYIDSCLSYTDLSGWTDEYKTNVRKYTEAQLDAWEQVGGWFFWCWKTESAPEWDFQALTNAGLIPQPLNDRQYPNQCGY
What is the function of this protein?
Beta-glucanases participate in the metabolism of beta-glucan, the main structural component of the cell wall.  It could also function biosynthetically as a transglycosylase (By similarity).
What are the official names of this protein?
Glucan 1,3-beta-glucosidase, Exo-1,3-beta-glucanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL13_BURCJ
Sequence: MKTFSAKAHEVTREWYVIDATDKVLGRVASEVARRLRGKHKPEFTPHVDTGDFIIIINASKLKVTGNKTLDKKYYRHSGYPGGIYETTFGKMQERFPGRALEKAVKGMLPKGPLGYAMIKKLKVYAEATHPHSAQQPKALEI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: LEG9_RAT
Sequence: MAFFSTQPPYMNPVIPFTGIIQGGLQNGLQITLQGTVHPFPNRIAVNFQTGFSGNDIAFHFNPRFEEGGYVVCNTKQNGKWGPEERKMQMPFQKGMPFELCFLVQRSEFKVMVNKNFFVQYSHRVPYHLVDTISVSGCLHLSFINFQNSTAAPVQPVFSTMQFSQPVQFPRMPKGRKQRTQGFQPALQAPVAQTIIHTVHSIPGQMLSTPGIPPMAYPTPAYTIPFFTSIPNGFYPSKSINISGVVLPDAKRFHINLRCGGDIAFHLNPRFNEKVVVRNTQINNSWGPEERSLPGRMPFNRGQSFSVWILCEGHCFKVAVDGQHICEYYHRLKNLPDINTLEVAGDIQLTHVQT
What is the function of this protein?
Binds galactosides (By similarity).  Has high affinity for the Forssman pentasaccharide (By similarity).  Ligand for HAVCR2/TIM3 (By similarity).  Binding to HAVCR2 induces T-helper type 1 lymphocyte (Th1) death (By similarity).  Also stimulates bactericidal activity in infected macrophages by causing macrophage activation and IL1B secretion which restricts intracellular bacterial growth (By similarity).  Ligand for P4HB; the interaction retains P4HB at the cell surface of Th2 T helper cells, increasing disulfide reductase activity at the plasma membrane, altering the plasma membrane redox state and enhancing cell migration (By similarity).  Ligand for CD44; the interaction enhances binding of SMAD3 to the FOXP3 promoter, leading to up-regulation of FOXP3 expression and increased induced regulatory T (iTreg) cell stability and suppressive function (By similarity).  Promotes ability of mesenchymal stromal cells to suppress T-cell proliferation (By similarity).  Expands regulatory T-cells and induces cytotoxic T-cell apoptosis following virus infection (By similarity).  Activates ERK1/2 phosphorylation inducing cytokine (IL-6, IL-8, IL-12) and chemokine (CCL2) production in mast and dendritic cells (By similarity).  Inhibits degranulation and induces apoptosis of mast cells (By similarity).  Induces maturation and migration of dendritic cells (By similarity).  Inhibits natural killer (NK) cell function (By similarity).  Can transform NK cell phenotype from peripheral to decidual during pregnancy (By similarity).  Astrocyte derived galectin-9 enhances microglial TNF production (PubMed:25158758).  May play a role in thymocyte-epithelial interactions relevant to the biology of the thymus.  May provide the molecular basis for urate flux across cell membranes, allowing urate that is formed during purine metabolism to efflux from cells and serving as an electrogenic transporter that plays an important role in renal and gastrointestinal urate excretion (PubMed:8995305).  Highly selective to the anion urate (PubMed:8995305).
What are the official names of this protein?
Galectin-9, Gal-9, 36 kDa beta-galactoside-binding lectin, Urate transporter/channel, UAT.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Secreted. Note=May also be secreted by a non- classical secretory pathway. Secreted by mesenchymal stromal cells upon IFNG stimulation.
Protein: BROX_XENTR
Sequence: MTHWFHRNPLKATAPVSFNFYGVASTQAASKICSDLRSTRARLLELFSDITCNHEMMKNATDAYFSLLLGFIDSLDGGTQDNKLRYIQNFKWTDTLQGNAPSAQQDAVFELVSMGFNVALWYTKYASRLAGKEDITEEEAKEVHRSLKIAAGVFKHLKENHIPKLITPVEKGRDLETRVIDAYTVQCQAEAQEVTIARAIELKHNPGLIAALAYETANYYQKVDHTLATLDPVYIAKWRSYTQLKMCFYMAYSYCYHGQTLLSADKCGEAIRSLQEAEKFYGKAEALCKEYGETKGPGTTAKPSGHLFFRKMGTLVRNTLEKCQRENGFIYFQKVPPEAPQLELKANYGLVEPVPFEFPAMTSQWSPETHTGFDLTKRPKDDSAKPKKEEEVKPMKEPDIKPQKDSGCQIS
What is the function of this protein?
Nuclear envelope-associated factor that is involved in the nuclear envelope ruptures during interphase (NERDI) repair.
What are the official names of this protein?
BRO1 domain-containing protein BROX, BRO1 domain- and CAAX motif-containing protein.
What is the protein family that this protein belongs to?
Belongs to the BROX family.
What are the subcellular locations of this protein?
Membrane; Lipid-anchor.
Protein: TRPB_TOLAT
Sequence: MTLLDPFFGEFGGMYSPQILMPVLLELEKAFVDAKDDPEFQAEFQHLLTEYAGRPTPLTLCRNLTKGTKTKIYLKREDLLHGGAHKTNQVLGQALLAKRMGKTRIIAETGAGQHGVATALACALLDLPCRIYMGAVDCERQKPNVFRMRLMGAEVIPVHAGSSTLKDACNEAMRDWTANYKDTHYILGTAAGPHPFPTIVREFQRMIGEEAKEQILKAEGRLPDAVVACVGGGSNAIGMFATFIEEEGVRLIGVEPAGHGIETGKHGAPIGHARKGIYLGMVSFLMQNEDGQVEESHSISAGLDFPSVGPQHAYLSSIGRAQYPSVTDQEALDAFQELSLREGIIPALESSHALAHALKMARSEPEKEQILIVNLSGRGDKDIFTVANALEGEGALS
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: ISPG_HAEIN
Sequence: MSAFQPTIKRRESTKIYVGNVPIGGDAPIAVQSMTNTRTTDVEATVAQIKSLERVGADIVRVSVPTMDAAEAFKQIKQQVNVPLVADIHFDYRIALKVAEYGVDCLRINPGNIGREDRVRAVVDCARDKNIPIRIGVNAGSLEKDLQEKYGEPTPEALLESALRHVEILDRLNFDQFKVSVKASDVFLAVESYRLLAKAIKQPLHLGITEAGGARAGAVKSAVGLGMLLAEGIGDTLRVSLAADPVEEIKVGFDILKSLRIRSRGINFIACPTCSRQEFDVIGTVNALEQRLEDIITPMDVSIIGCVVNGPGEALVSDLGVTGGNKKSGYYLDGERQKERFDNEDIVNQLEAKIRAKVARQDPKNRII
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: PGAP2_CRIGR
Sequence: MYQVPLTLDRDGTLVRLRFTMVALITVCCPLVAFLFCILWSLLFHFKETTSTHCGVPNYLPSVSSAIGGEVPQRYVWRFCIGLHSAPRFLAAFAYWNHYLSCASPCPGYRLLCRLNFSLNVVENLALLVLTYVSSSEDFTIHENAFIVFIAASLSYMLLTCILWRLTKKHTVSQEDRKSYSWKQRLFIINFISFFSALAVYFRHNMYCEAGVYTIFAILEYTVVLTNMAFHMTAWWDFGNKELLITSQPEEKRF
What is the function of this protein?
Involved in the lipid remodeling steps of GPI-anchor maturation.  Required for stable expression of GPI-anchored proteins at the cell surface.
What are the official names of this protein?
Post-GPI attachment to proteins factor 2, FGF receptor-activating protein 1.
What is the protein family that this protein belongs to?
Belongs to the PGAP2 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PXL2C_TAKRU
Sequence: MAAVLSPITRQVSKEPRELQRVCVDIRLEDVQDCLVYDRRGGSVPFKNLYQHTKSVIIFVRNFLCYACKEYVEDLSKIPEDVFEGKVLGIRLIVIGQSMHHHIEAFCTLTGYPYEIYVDPDRHIYQKLGMKREETFTDSAQPSPHVKSGIFAGQMKSIWRAMTGPIFDFQGDLHQQGGAIIVGPGAQVHFCHFDTNRLDHMPINWLLQLAGVQQTLDFSKPKIMHV
What are the official names of this protein?
Peroxiredoxin-like 2C, AhpC/TSA antioxidant enzyme domain-containing protein 1, Thioredoxin-like protein AAED1, fmHP.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin-like PRXL2 family. PRXL2C subfamily.
Protein: DEOD_BACC1
Sequence: MSVHIEAKQGEIAESILLPGDPLRAKYIAETFLEDVTCYNNVRGMLGFTGTYKGKRVSVQGTGMGVPSISIYVNELIQSYGVKNLIRVGTCGAIQKDVKVRDVIIAMTACTDSNMNRLTFPGFDFAPAANFDLLKKAYDAGTEKGLHVRVGNVLTADVFYRESMDMVKKLGDYGVLAVEMETTALYTLAAKYGVNALSVLTVSDHIFTGEETTSEERQTTFNEMIEIALDAAIQQ
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: PKG1_ADEM1
Sequence: MESRGKHRLKKNGESKENLGEHEQARIGFHRNGDSADSLSSPVAEPNFSSPGGRSSNSILHCPPQSPEQGNNLDCLVGEELQFLWPRLQCLQHTLSNLPLSEGLKPLMNFETVEDLAALAGKGLLQELKHDYEILCKSLNSAAPLLSPEGNCESLNYSLQPLIAIVYGPTGSGKSQLLRNLLSCHLIDPSPETVFFVVPQIDMIPPQEMSAWNAQLVEGNYTCGPQQTIVPKSGTLKPRLITLTYDDLTADHNYDVTHPQNIFAQAAQRGPICIIVDECMEELGKHKSIAKFFHAFPSKLHDRFPQCTGYSVFVVLHNMNPRKDQAGNIATLKIQSKCHIISPKMQPSQVARFINTYTKAMPTAITLLLKDIFHHNANHINYDWIIYNTSPEHECMQWMYLHPQNGLMPMYLNVQTILYQLLEKIDKVLRQRQRWNTAYSKKCDKLANK
What is the function of this protein?
Component of the packaging machinery which encapsidates the viral DNA into preformed capsids and transcriptional activator of the viral major late promoter (MLP).  Binds, along with packaging proteins 2 and 3, to the specific packaging sequence on the left end of viral genomic DNA and displays ATPase activity thereby providing the power stroke of the packaging machinery.  The activity of packaging protein IVa2 is stimulated by protein 33K which acts as a terminase.  May be the protein that pumps DNA into the capsid powered by ATP hydrolysis.  Specifically binds to the 5'-CG-3' nucleotides of the repeats making up the packaging sequence.  Component of the DEF-A and DEF-B transcription factors that bind downstream elements of the major late promoter (MLP), and stimulate transcription from the MLP after initiation of viral DNA replication.  DEF-A is a heterodimer packaging proteins 1 and 2 and DEF-B is a homodimer of packaging protein 1.
What are the official names of this protein?
Packaging protein 1, Packaging protein IVa2.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae packaging protein 1 family.
What are the subcellular locations of this protein?
Virion. Host nucleus, host nucleoplasm. Host nucleus, host nucleolus. Note=Located at a unique vertex of the capsid. Present in about 6-8 copies per virion.
Protein: TSAD_GEOSL
Sequence: MLVLAIETSCDETAAALVRDGRSILSSVVSSQVKDHAVYGGVVPEIASRKHLETIPAVIGEALRLADVTLDHVEGVAVTQGPGLAGALLVGLSVAKSIAFARRLPLVGVNHIEAHLAAIFLEREVAYPYLALVVSGGHSHLYRVDGIGRCTTLGQTLDDAAGEAFDKVAKLLGLPYPGGIEIDRLASAGDPDAIAFPRPLLHDGSFNFSFSGLKTAVLSAVKKQGLPEGKSLADFCASFQKAVCHVLVEKTFRAAEAAGIDRVVVAGGVACNSALRREMAHAAAARGVELMIPSPSLCGDNAAMIAVPGDYYLRCGEQGGLALDARVNWPLDLLGSGREG
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCJF_SALEP
Sequence: MSEPLKPRIDFAEPLKEEPTSAFKAQQTFSEAESRTFAPAAIDERPEDEGVAEAAVDAALRPKRSLWRKMVMGGLALFGASVVGQGVQWTMNAWQTQDWVALGGCAAGALIIGAGVGSVVTEWRRLWRLRQRAHERDEARELLHSHSVGKGRAFCEKLAQQAGIDQSHPALQRWYAAIHETQNDREIVGLYAHLVQPVLDAQARREISRFAAESTLMIAVSSLALVDMAFIAWRNLRLINRIATLYGIELGYYSRLRLFRLVLLNIAFAGASELVREVGMDWMSQDLAARLSTRAAQGIGAGLLTARLGIKAMELCRPLPWIDNDKPRLGDFRRQLIGQLKETLQKSKSSPEK
What are the official names of this protein?
UPF0283 membrane protein YcjF.
What is the protein family that this protein belongs to?
Belongs to the UPF0283 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLNE_SERP5
Sequence: MLPLSAALQTQAQNIVQRFQETQGADCALSSQELWVLASSDFVCDMLQSQPEWLATLRKQPPVADEWQHYAAWLQDDLEEVRDEAQLMRALRLFRRETLVRIAWAQALGQCSTQETLLQLSGLAETLIVSARDWLYQTCCREWGTPCNAQGVPQPLLILGMGKLGGGELNFSSDIDLIFAYPENGQTQGGRRELDNAQFFTRLGQRLIKALDQQTIDGFVYRVDMRLRPFGDSGPLVMSFAALEDYYQEQGRDWERYAMVKARLMGGSEDAYSEELRKTLRPFVFRRYIDFSVIQSLRNMKGMIAREVRRRGLKDNIKLGAGGIREIEFITQVFQLIRGGREPALQGRSLLPTLQAVGELGLLEPQQVQAMSASYLFLRRLENLLQAIADQQTQTLPQDELDQARLAWGMGFDDWSALLLALDHHMQAVRAVFNDLIGDDSPDVGEDPDYQHYHSLWQDALEENELAPLTPHLDEEARRQMLRTIAEFRHDVDKRTIGPRGRDVLDQLMPRLLAEVCPRQDAPTALLRLTQLLLSIVTRTTYLELLVEYHAALSHLIRLCAASPMVANQLSRYPLLLDELLEPATLYQPVAPDAYRSELRQYLLRVPEDDEEQRLEALRQFKQAQQLRIAAGDISGALPVMKVSDHLTYLAEAIIDTVVQQAWNDMVARYGQPTHLQEREGRGFAVIGYGKLGGWELGYSSDLDLVFILDCPPEVMTDGDRSIDGRQFYLRLAQRVMHLFSTRTSSGILYEVDARLRPSGAAGMLVSTVEAFADYQQSEAWTWEHQALVRARIVHGDPLLHQQFDVIRREILCKPRDLETLKREVREMREKMRNHLGNKQRELFDIKADEGGITDIEFIAQYLVLGYAAAEPRLTRWSDNVRIFELMANYDIMPEEEARALTQAYVTMRDEIHHLALQEHSGKIGNGQFAAEREQVRASWAKWLG
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia.  When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity.  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity.  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.