PharMolix/UniProtQA huggingface dataset:
Protein: B2MG_CEBAL
Sequence: MARFVVAALLVLLCLSGLEAIQHAPKIQVYSRHPAENGKPNFLNCYVSGFHPSDIEVDLLKNGKKIEKVEHSDLSFSKDWSFYLLYYTEFTPNEKDEYACRVSHVTFPTPKTVKWDRNM
What is the function of this protein?
Component of the class I major histocompatibility complex (MHC).  Involved in the presentation of peptide antigens to the immune system (By similarity).
What are the official names of this protein?
Beta-2-microglobulin.
What is the protein family that this protein belongs to?
Belongs to the beta-2-microglobulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SPTB1_HUMAN
Sequence: MTSATEFENVGNQPPYSRINARWDAPDDELDNDNSSARLFERSRIKALADEREVVQKKTFTKWVNSHLARVSCRITDLYKDLRDGRMLIKLLEVLSGEMLPKPTKGKMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLVLGLIWTIILRFQIQDIVVQTQEGRETRSAKDALLLWCQMKTAGYPHVNVTNFTSSWKDGLAFNALIHKHRPDLIDFDKLKDSNARHNLEHAFNVAERQLGIIPLLDPEDVFTENPDEKSIITYVVAFYHYFSKMKVLAVEGKRVGKVIDHAIETEKMIEKYSGLASDLLTWIEQTITVLNSRKFANSLTGVQQQLQAFSTYRTVEKPPKFQEKGNLEVLLFTIQSRMRANNQKVYTPHDGKLVSDINRAWESLEEAEYRRELALRNELIRQEKLEQLARRFDRKAAMRETWLSENQRLVAQDNFGYDLAAVEAAKKKHEAIETDTAAYEERVRALEDLAQELEKENYHDQKRITARKDNILRLWSYLQELLQSRRQRLETTLALQKLFQDMLHSIDWMDEIKAHLLSAEFGKHLLEVEDLLQKHKLMEADIAIQGDKVKAITAATLKFTEGKGYQPCDPQVIQDRISHLEQCFEELSNMAAGRKAQLEQSKRLWKFFWEMDEAESWIKEKEQIYSSLDYGKDLTSVLILQRKHKAFEDELRGLDAHLEQIFQEAHGMVARKQFGHPQIEARIKEVSAQWDQLKDLAAFCKKNLQDAENFFQFQGDADDLKAWLQDAHRLLSGEDVGQDEGATRALGKKHKDFLEELEESRGVMEHLEQQAQGFPEEFRDSPDVTHRLQALRELYQQVVAQADLRQQRLQEALDLYTVFGETDACELWMGEKEKWLAEMEMPDTLEDLEVVQHRFDILDQEMKTLMTQIDGVNLAANSLVESGHPRSREVKQYQDHLNTRWQAFQTLVSERREAVDSALRVHNYCVDCEETSKWITDKTKVVESTKDLGRDLAGIIAIQRKLSGLERDVAAIQARVDALERESQQLMDSHPEQKEDIGQRQKHLEELWQGLQQSLQGQEDLLGEVSQLQAFLQDLDDFQAWLSITQKAVASEDMPESLPEAEQLLQQHAGIKDEIDGHQDSYQRVKESGEKVIQGQTDPEYLLLGQRLEGLDTGWNALGRMWESRSHTLAQCLGFQEFQKDAKQAEAILSNQEYTLAHLEPPDSLEAAEAGIRKFEDFLGSMENNRDKVLSPVDSGNKLVAEGNLYSDKIKEKVQLIEDRHRKNNEKAQEASVLLRDNLELQNFLQNCQELTLWINDKLLTSQDVSYDEARNLHNKWLKHQAFVAELASHEGWLENIDAEGKQLMDEKPQFTALVSQKLEALHRLWDELQATTKEKTQHLSAARSSDLRLQTHADLNKWISAMEDQLRSDDPGKDLTSVNRMLAKLKRVEDQVNVRKEELGELFAQVPSMGEEGGDADLSIEKRFLDLLEPLGRRKKQLESSRAKLQISRDLEDETLWVEERLPLAQSADYGTNLQTVQLFMKKNQTLQNEILGHTPRVEDVLQRGQQLVEAAEIDCQDLEERLGHLQSSWDRLREAAAGRLQRLRDANEAQQYYLDADEAEAWIGEQELYVISDEIPKDEEGAIVMLKRHLRQQRAVEDYGRNIKQLASRAQGLLSAGHPEGEQIIRLQGQVDKHYAGLKDVAEERKRKLENMYHLFQLKRETDDLEQWISEKELVASSPEMGQDFDHVTLLRDKFRDFARETGAIGQERVDNVNAFIERLIDAGHSEAATIAEWKDGLNEMWADLLELIDTRMQLLAASYDLHRYFYTGAEILGLIDEKHRELPEDVGLDASTAESFHRVHTAFERELHLLGVQVQQFQDVATRLQTAYAGEKAEAIQNKEQEVSAAWQALLDACAGRRTQLVDTADKFRFFSMARDLLSWMESIIRQIETQERPRDVSSVELLMKYHQGINAEIETRSKNFSACLELGESLLQRQHQASEEIREKLQQVMSRRKEMNEKWEARWERLRMLLEVCQFSRDASVAEAWLIAQEPYLASGDFGHTVDSVEKLIKRHEAFEKSTASWAERFAALEKPTTLELKERQIAERPAEETGPQEEEGETAGEAPVSHHAATERTSPVSLWSRLSSSWESLQPEPSHPY
What is the function of this protein?
Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane.  It associates with band 4. 1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane.
What are the official names of this protein?
Spectrin beta chain, erythrocytic, Beta-I spectrin.
What is the protein family that this protein belongs to?
Belongs to the spectrin family.
Protein: RS14Z_LEPIC
Sequence: MAKTSITVRHQRKKKFEVREYNRCPICGRSRGYLRRFDMCRICFRKLASGAQIPGVVKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: RR19_ORYSA
Sequence: MTRKKTNPFVAHHLLAKIEKVNMKEEKETIVTWSRASSILPAMVGHTIAIHNGKEHIPIYITNPMVGRKLGEFVPTRHFTSYESARKDTKSRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YBJN_ECO57
Sequence: MTSLVVPGLDTLRQWLDDLGMSFFECDNCQALHLPHMQNFDGVFDAKIDLIDNTILFSAMAEVRPSAVLPLAADLSAINASSLTVKAFLDMQDDNLPKLVVCQSLSVMQGVTYEQFAWFVRQSEEQISMVILEANAHQLLLPTDDEGQNNVTENYFLH
What are the official names of this protein?
Uncharacterized protein YbjN.
Protein: LSPA_LISIN
Sequence: MYYYLITLAVIALDQLTKWIVVQNMEIGQKIEVIPGFLYWTSYRNDGAAWSILEGHMWFFYLITVIVIGIIIYIMQKYAKGKRLFSISLAFILGGAIGNFIDRILHQEVVDFVQTVWGNYYFPIFNVADAALSVGVVLMLVYVFVDDRKTKGIK
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EFGM_HUMAN
Sequence: MRLLGAAAVAALGRGRAPASLGWQRKQVNWKACRWSSSGVIPNEKIRNIGISAHIDSGKTTLTERVLYYTGRIAKMHEVKGKDGVGAVMDSMELERQRGITIQSAATYTMWKDVNINIIDTPGHVDFTIEVERALRVLDGAVLVLCAVGGVQCQTMTVNRQMKRYNVPFLTFINKLDRMGSNPARALQQMRSKLNHNAAFMQIPMGLEGNFKGIVDLIEERAIYFDGDFGQIVRYGEIPAELRAAATDHRQELIECVANSDEQLGEMFLEEKIPSISDLKLAIRRATLKRSFTPVFLGSALKNKGVQPLLDAVLEYLPNPSEVQNYAILNKEDDSKEKTKILMNSSRDNSHPFVGLAFKLEVGRFGQLTYVRSYQGELKKGDTIYNTRTRKKVRLQRLARMHADMMEDVEEVYAGDICALFGIDCASGDTFTDKANSGLSMESIHVPDPVISIAMKPSNKNDLEKFSKGIGRFTREDPTFKVYFDTENKETVISGMGELHLEIYAQRLEREYGCPCITGKPKVAFRETITAPVPFDFTHKKQSGGAGQYGKVIGVLEPLDPEDYTKLEFSDETFGSNIPKQFVPAVEKGFLDACEKGPLSGHKLSGLRFVLQDGAHHMVDSNEISFIRAGEGALKQALANATLCILEPIMAVEVVAPNEFQGQVIAGINRRHGVITGQDGVEDYFTLYADVPLNDMFGYSTELRSCTEGKGEYTMEYSRYQPCLPSTQEDVINKYLEATGQLPVKKGKAKN
What is the function of this protein?
Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.  Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis.
What are the official names of this protein?
Elongation factor G, mitochondrial, EF-Gmt, Elongation factor G 1, mitochondrial, mEF-G 1, Elongation factor G1, hEFG1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
Protein: ATPE_METPP
Sequence: MATIHVDVVSAEASIFSGEAKFVALPGEMGELGIYPRHTPLITRIKPGAVRVERADNGEEEFVFVAGGILEVQPDRVTVLADTAIRGHDLDEAKAEEAKKAAEEAMKNAKSDIDFAKAQGEFAAMAAQIAALRKFRKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RF1_STRZT
Sequence: MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNRDTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILLLPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGGFKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMLEVEEVEYDIDPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIRARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTILSGKLDEVVDALVLYDQTQKLEELNK
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRAG1_RAT
Sequence: MSACSDFVEHIWKPGSCKNCFCLRSDHQLTAGHPKARASSLPAGARLPARPEICRLEDEGVNGLAYSKPTIAVKPTMMTSETADLWTEASLSAEVPKVNWRRTPGKLLLQKQEDGPIVYLGSFRGMQKAAGPLACTDSNSRCPPAYTMVGLHNLEARVDRNTALQPVNFQEEKAGREELPSAQESFRQKLAAFTGMTSSCLKGPRPCTSPQPLRESLPSEDDSDQRCSPSGDSEGGEYCSILDCRPESRDAVHNTEGSGRRRGDCSPICWEQGTCTRPTEEEKQALNFPRECCGQGSTANPPHLGPKKPSLNSEAASSSDGLSCGSSRSGANSPFAPHLENDYCSLVKEPTSVKQQDSGCHLVNSGKYVGQAVDLQPPALPREAVQPEPIYAESAKRKKAAPVPQRPEPKKEQVSSGQVWTGDTWSQKTPSGWSQEREGPNAAPQVATTITVIAAHPEEDHRTIYLSSPDSAVGVQWPRGSLNQDLHGSGEEPLVVQGLSSRESHPHNMTENSSKEKPAIPPKLSKSSPGGSPVSPAAPPLTDHSDGNTSGSSVGSQPSSRVPTNLTSSCQTNGVAAGDPAKCPPQANSSVLDQRRPRYQTGAWSRQCRIEEEEEVGQELLSQSWGRELENGIADHSNSSTWHRLHPIDGASGQNGKTNSGMSKSASFAFEFPKDRGRLESFSPPPPPPKSRHLLKMNKSSSDLEKVSQSSAESLSPSFRGAHVSFTTGSTDSLASDSRTCSDGGPSCEATHSPTISGKKLFAPVPFPSGSTEDVSPSGPAQPPPLPQKKIVSRAASSPDGFFWTQGSPKPRTASPKLNLSHSETNVCAHDEPPLSYSLNSGNHPHHVFSSSEPLEKAFKGSVPWAPALGPANSKGGCGSPNLQGRAATSTSSSQLSVSSQASTGSSQLQLHSLLSSISSKEGTYAKLGGLYTQSLARLVTKCEDLFMGGLKTELRFDENSWSLFKLICNKPCCDSGDAIYYGATCSKDPDSIYAVKICKTPEPKSASYCSPSVPVHFNIQQDCGHFVASVPSSMLAFPDTSSKDPAPAAPSHTPAQEQDCVVVITREVPHQTASDFVRDSVASHRAEPEVYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCNPQSSPGPSANPSVPTTTSRCPSAAPAATTACQGGPGEKHLPRLIISNFLKAKQKPGGTTNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIYELLHQPNPFEVRAQLRERDYRREDLPPLPTLSLYSPGLQQLAHLLLEADPIKRIRIGEAKRVLQCLLWGPRRELVEQPCPSEEVLCNTLHNWIDMKRALMMMKFAEKAVERRRGVELEDWLCCQYLASAEPGALLQSLKLLQLL
What is the function of this protein?
Catalytically inactive protein kinase that acts as a scaffold protein (PubMed:29503074).  Functions as an effector of the small GTPase RND2, which stimulates RhoA activity and inhibits NGF-induced neurite outgrowth (PubMed:16481321).  Promotes Src family kinase (SFK) signallig by regulating the subcellular localization of CSK, a negative regulator of these kinases, leading to the regulation of cell morphology and motility by a CSK-dependent mechanism (PubMed:27116701, PubMed:21873224).  Acts as a critical coactivator of Notch signaling (By similarity).
What are the official names of this protein?
Inactive tyrosine-protein kinase PRAG1, PEAK1-related kinase-activating pseudokinase 1, Pragma of Rnd2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell junction, focal adhesion. Note=Colocalized with NOTCH1 in the nucleus.
Protein: YQGA_BACSU
Sequence: MKQGKFSVFLILLLMLTLVVAPKEKAEAASSGWQPVSGISGCKIRVITDAYTYTKSATSIDAYAETNGKCGKLNYKSFGVSIVEGGDIGPQYSGYFSSRTPTKKFYFSKLPKPTGTPWAVGLSVYKGKAKGAAFVYINPQKR
What are the official names of this protein?
Cell wall-binding protein YqgA.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: TIG_CELJU
Sequence: MQVSLETTSGLERRLTVGVPAEQVENEVENRLKQAARNVTIKGFRKGKVPLSVVKQRFGAGIRQEVVGDVINRSFYAAVQKENLKPAGQPSIQPKQLSAGQDLEYIAVFEVYPSVELSDLSVFEITRHKAEVTDVDVDNMIDVLRKHQATWTQVERAAADGDQVNINFVGTKDGVEFAGGKADNQNLILGSNSMIPGFEAGLVGLKSGDQKTLALTFPEDYHSEELKGAAVEFAVTVNSVSEAVLPELNKEFFQKFGVEKGGEKQFRKEVKANMERELGNALKAKVKGQVMDALVASHTVDVPKALVANEIQVLRNQMLQRFGGQQQNFDVKSLLPDTMFQEEASRRVTLGLIVGEIVKSAKLKPDAKRIKSMIEEIASTYQEPQEVIDYYNSNQELLAGVESAVLEDQVVDHILSKAKVSDVDSTYDDVIKSKAQR
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: SRB8_ASPCL
Sequence: MIPHSSAGVQPWGHPLRAVHSASGLTDIPHALGQPDLHPEQSSMPAPQPQTGPSAVIDLTANGGEAQEREHPAKRLRLDIHSGSNARDGSPASAGLGEPKSTPVSTSSKPPPLSWRGRPVWSFQALLSEVPGAGEPNVESTTAAAQDVKPLSPPSFPAPPWKHSPADPTASSAAGLRGVTPAKEVRTTPYHIEVPSVAPVLRGDKVADFLPWTGNHPEDVLNEQTAKQGYYDRTQVSQNESNTARPSLYAQLKHRSGLQMLSSVFAAALEKRQGHSMVTAPSTFKPPPRVTLTDNKREAWLRDLANPTVPLRRLSRTIPHGIRGRVLLDQCLTKWVPVGRAVWLAKCVGANEIRAFKRKGTSGALAIGLEAKWVRDWTTNVQQFLDGVITSCGVADWKLKMTYAVSLTARLFFEQLLDHDQYLGWFLSSLEAAPLNTLPVWLLMLGIYWNHLLRYRKRGRRLAELLLEKLSKANKLDSSNTLRPLADRLSLHIRKLTLEHTSSAVLPHSWDKYKDLLSSCLNMKDSVHRAVIQNLSERNARVQRPRKCQETANQPPQQRVIQLFDSIRSTHDVTAVSIASLSAIDDKAALVFKLLEWVSTPFRHGICRVYTGARLLRKWKVAGVDVDSCIISFLAEGHDGSHLNMDNIYHIISELVRSQTFSVGRYLQWLMAKGVADCSKDSHQHHKHLSDDLELLLQLPVSRLPDHVRNLRNTLLHRAGIEVSKEEAMIATLKASIAQRLPNIFSSVTDSAMSCDVAQSELTWAVKSEIGQWIRRGVTEGRRGSTGKFQIAIGQPVLSADEFYSIRDILEGFGDLSMLADVLNQATNCDDGLILASAADTVNYHFQSFSVIGASTGLFRRFVESYARLKRLGVTSLDLILSLIDLGLHLPGEFNTVALLRQDLGRIENKSSMAAPSPLSDHIPATFNETDSLFPEKLDQLLFSGGGMDESTMDAIFNALITSLGRAEDRVKLSANDICRYLAYLRPFHPKHFDIMLIRWICGLLKSSTRTMLSRVLPPLIGVGCVTIQAFIFLVRRLLQSEKVASMIPHPNDLKIDLLQLLVPPPAGQSRYFDMVTYRFHLSQKEFLSKHPEETFNIIRDAIALIDSQDQDNHSDQGQMNLNQNAMVLLQILLTKNPESAVQYCTEKLITQHSTSMMVLTKALDTLLGFDTGPDPPNVSVAEKVIELTNDFSLPFCQLKLQTLFNAEAGSNVKNEIVDVMFKAAIADSRSRRSNWVGLVRLMNQDAVRQIRERAEKSFFAIPLFEEANEGRSMNNGTSLETAKLYLTIIEKLAYSIPDSGVQGVGSVLVEKMDLLLHKLVSMQTSYNGSTEMRHGIDAEQVIQSRTEFERSLAFWFSALLRMIVLHRSAFSIPPAPKSSASQEQTRLLISIFCITLARLPDSVLRLFPTADYFPHSMRQGDHRPCPGILLQTHALDVAASLIDMFPDELRHQCARFLKDKCSPFAQSQNDSRFLYLLGPLGDGPTSNATLPVSIPSPAASGSTPAPTPSGSLTAGPSNPPQPASASLGVPTGLPEGLNCGASHLCLQYRGRAIGAYPVRPWELLEDAAPIAGTNDTAVSLGYFDARRVRA
What is the function of this protein?
Component of the srb8-11 complex.  The srb8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription.  The srb8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator.  It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 12, Mediator complex subunit 12.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 12 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SEC11_ARTBC
Sequence: MFAELAPYLSNPRQTLAQLLNFALVLSTAFMGWKALSVYTNSSSPIVVVLSGSMEPAFQRGDLLFLWNNSPRAEVGEIVVYNVQGKDIPIVHRVIKAFGTGDGGKKSQRRLEREADKRSGPGLSSPVSHQMLTKGDNNIADDTELYAQGQDYLDRKLDIVGSVRGYIPAVGYVTIMLAENPWMKTVLLGIMGVMVMLQRE
What is the function of this protein?
Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity).  Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids (By similarity).
What are the official names of this protein?
Signal peptidase complex catalytic subunit SEC11, Signal peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26B family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: VM2M2_DEIAC
Sequence: FPYQGSSIILESGNVNDYEVVYPRKVTALPKGAVQQKYEDTMQYEFKVNGEPVVLHLEKNKGLFSKDYSETHYSPDGRRITTHPLVEDHCYYRGRIRNDADSTASISACNGLKGHFKLRGETYLIEPMKISNSEAHAVYKYENVEKEDEAHKMCGVTQNWESYEPIKKASQLIVTPEHQRYMEIVIVVDHSMYTKYNGDSDKIKTWIYEMSNTIRESYRYLYIDTSVAAIEIWSEKDLINVETSAKNTLESFGEWRARDLIHRISHDNAQLLTATDLDGPTIGLAYVASMCDPKRSVGVVQDHSSVNHLVAITLAHEIAHNLGVRHDEGSCSCGSGYTCIMSPVINPDAMKYFSDCSYIQCWDYIMKENPPCILNKPLRTDTVSTPVSGNELLEAGKDYDRDSSANPCYDAATCKLNQGAQCTAGPCCDQGRFKEEGTICRRARGDDLDDYCNGISGDCPRNPYHA
What is the function of this protein?
Inhibits platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen.  Acts by inhibiting fibrinogen interaction with platelet receptors GPIIb/GPIIIa (ITGA2B/ITGB3) (By similarity).
What are the official names of this protein?
Zinc metalloproteinase/disintegrin.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-II subfamily. P-IIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HFQ_SHIBS
Sequence: MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVSHHSNNAGGGTSSNYHHGSSAQNTSAQQDSEETE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: SMI7B_XENLA
Sequence: MIGDLLLFGTLLVNAGAVLNFKLKKKESQGFGDDLTEATTGDNIREFLLSLRYFRIFIALWNIFMMFCMVVLFGS
What are the official names of this protein?
Small integral membrane protein 7-B.
What is the protein family that this protein belongs to?
Belongs to the SMIM7 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: MARE1_CHICK
Sequence: MAVNVYSTSVTSDNLSRHDMLAWINESLQLTLTKIEQLCSGAAYCQFMDMLFPGSVALKKVKFQAKLEHEYIQNFKVLQAGFKRMGVDKIIPVDKLVKGKFQDNFEFVQWFKKFFDANYDGKEYDPVAARQGQETVAPNLVAPVVNKPKKPLAPQRPIVAQRTPATPKGSTGMVKKAAGDDESAGLIEQINVLKLTVEDLEKERDFYFGKLRNIELICQENEGENDPVLQRIVEILYATDEGFVIPDEGAPQEEQEEY
What is the function of this protein?
Plus-end tracking protein (+TIP) that binds to the plus-end of microtubules and regulates the dynamics of the microtubule cytoskeleton.  Promotes cytoplasmic microtubule nucleation and elongation.  Involved in mitotic spindle positioning by stabilizing microtubules and promoting dynamic connection between astral microtubules and the cortex during mitotic chromosome segregation.
What are the official names of this protein?
Microtubule-associated protein RP/EB family member 1.
What is the protein family that this protein belongs to?
Belongs to the MAPRE family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Golgi apparatus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole.
Protein: SYP73_ARATH
Sequence: MGVIDLITRVDSICKKYEKYDINRQRDANVSGDDAFSRLYSAVEYALETVLQKTEDLSSETNKAKAVAMNAEIRRTKARLLEGIPKLQRLSLKKVKGLSKEELDARNDLVLSLRDKIEAIPESSAPVVGGWEASTSYSNIRFDTNVSDDRIGSEYFQPTGESDQFKQEYEMKRIKQARLDYIAEGLDTLKNMAQDINEELDRQEPLMDEIDTKIDKAATDLKSTNVRLKDTVTKLRSSRNFCIDIILLCILLGIAAFIYNSVK
What is the function of this protein?
Vesicle trafficking protein that functions in the secretory pathway.
What are the official names of this protein?
Syntaxin-73, AtSYP73.
What is the protein family that this protein belongs to?
Belongs to the syntaxin family.
What are the subcellular locations of this protein?
Membrane; Single-pass type IV membrane protein.
Protein: TATA_CHLCH
Sequence: MFGLGGQELVLILLIVLLLFGAQKLPELAKGLGKGMKEFKRAQNEIEEEFNKSMDDNPKKEKATTASKS
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: COBT_METC4
Sequence: MGEIGGNALDGIHARVRTAPLADQAAIAAVRQRDRLLTKPPGSLGRLEAIVEWLAAWQGKSPPVLESAAAVVFAGNHGVAKHGVSAYPAEVTAQMVANFEAGGAAINQIAKANGLKLSIVPIDLDRPTADIIIADAMSVQECAAAVNLGASVAAADLDLLCIGEMGIGNTTPASAILQALFGGPAHIWVGPGTGVERDALTNKIRAVESAVARVIGTDGTSPLEFLRRLGGREIAALVGAIIEARHRRIPVLIDGFVATAAAAVVHAIEPGAIDHCLIGHLSAEPAHRRAVQALGKTPILELNMRLGEASGAALAAGIVRSALAVHTGMATFAEAGVTDRQT
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: 2A5T_ARATH
Sequence: MWKQILSKLPKKSSSKNHSSSSSSTSKSSDNGASKSGNSQTQNAPPVKPSADSGFKEGNLKGNGNGFTPYEALPGFKDVPNAEKQNLFVRKLSLCCVVFDFSDPTKNVKEKDIKRQTLLELVDYVASPNGKFSETVIQEVVRMVSVNIFRTLNPQPRENKVIDALDLEEEEPSMDPTWPHLQLVYEILLRLIASPETDTKLAKKYIDQSFVSRLLDLFDSEDPRERDCLKTVLHRIYGKFMVHRPFIRKSINNIFYRFVFETEKHNGIAEFLEILGSIINGFALPLKDEHKVFLVRALVPLHKPKSLQMYHQQLSYCITQFVEKDCKLADTVIRGLLKSWPVTNSSKEVMFLNELEEVLEATQPPEFQRCMVPLFRQVARCLNSLHFQVAERALFLWNNDHIENLIMQNRKVILPIIFPALERNTQKHWNQAVHSLTLNVQKIFNDIDAELFKDCLAKFREDESKEAEIGAKREATWKRLEEIGNQKQKSSL
What is the function of this protein?
The B regulatory subunit may modulate substrate selectivity and catalytic activity, and may also direct the localization of the catalytic enzyme to a particular subcellular compartment (By similarity).  Associates with the serine/threonine-protein phosphatase PP2A catalytic subunit C and regulatory subunit A to positively regulates beta-oxidation of fatty acids and protoauxins in peroxisomes by dephosphorylating peroxisomal beta-oxidation-related proteins (PubMed:25489022).  Required for the formation of the PP2A holoenzyme that negatively regulates brassinosteroid signaling by dephosphorylating and inactivating BRI1 in the cytoplasm (PubMed:26517938).
What are the official names of this protein?
Serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' theta isoform, AtB' theta, PP2A, B' subunit, theta isoform.
What is the protein family that this protein belongs to?
Belongs to the phosphatase 2A regulatory subunit B56 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Peroxisome.
Protein: RUVA_STRPD
Sequence: MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGIGPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGHTKARSNKAGNTQLDEAIEALLALGYKAKELKKIRAFFEETSETAEQYIKSALKLLMKG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: APT_CAMC1
Sequence: MKILDQKGKEFLLNSIRCINDFPKPGIVFRDITTLLNNKEAFNFLIDHLAARYEDANIDYIAGIESRGFIFGAALAARLRLPFVPIRKPKKLPFITLSQKYSLEYGVDEVQIHIDAFGEKAGARVLLMDDLIATGGTAKASVELINQTNATCVEACFLIDLVDLKGSEKLKSLTKIYSVLEV
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.