PharMolix/UniProtQA huggingface dataset:
Protein: LIPA_METPB
Sequence: MAVVLDLLNNDTRPKVEAPARPRHPEKAHRPDTAIQRKPDWIRVKAPGSKLWAETKDIVRANNLVTVCEEAGCPNIGECWEKRHATFMIMGDTCTRACAFCNVRTGLPESLDAAEPEKVADAVAKLGLHHVVVTSVDRDDLKDGGAEHFSRTIAAIRRASPGTTVEILTPDFLRKPGALEVVVAAKPDVFNHNLETVPGKYVTVRPGARYFHSVRLLQRVKELDPTIFTKSGIMVGLGEERNEVVQLMDDLRSAEVDFLTIGQYLQPTRKHHEVVRFVPPDEFKAYETTAYAKGFLLVSATPLTRSSHHAGEDFARLKAARLAKLGPAPVAVNA
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIG_VIBC3
Sequence: MLKIADKTFQSRLFTGTGKFSNRHVMAEALAASGSELVTMALKRIDLAQRDDDILAPLLSMQMNLLPNTSGAKNAADAVYAAELAREALATNWLKLEIHPDPKYLMPDPIETLLAAEQLVKQGFIVLPYCHADPVLCKRLEEVGCAAVMPLGSPIGSNQGLASKTFLEIIIDQAKVPVIVDAGIGSPSDAAQAMELGADAVLVNTAIAAAHDPIAMAKAFKLAVEAGRMAYESGLPSRVKMATASSPLTGFLDFVS
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBE2B_HUMAN
Sequence: MSTPARRRLMRDFKRLQEDPPVGVSGAPSENNIMQWNAVIFGPEGTPFEDGTFKLVIEFSEEYPNKPPTVRFLSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKRVSAIVEQSWNDS
What is the function of this protein?
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.  In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1.  H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation.  In vitro catalyzes 'Lys-11'-, as well as 'Lys-48'- and 'Lys-63'-linked polyubiquitination.  Required for postreplication repair of UV-damaged DNA.  Associates to the E3 ligase RAD18 to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164'.  May be involved in neurite outgrowth.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 B, E2 ubiquitin-conjugating enzyme B, RAD6 homolog B, HR6B, hHR6B, Ubiquitin carrier protein B, Ubiquitin-conjugating enzyme E2-17 kDa, Ubiquitin-protein ligase B.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
What are the subcellular locations of this protein?
Cell membrane. Nucleus. Note=In peripheral neurons, expressed both at the plasma membrane and in nuclei.
Protein: ACP_STAA1
Sequence: MENFDKVKDIIVDRLGVDADKVTEDASFKDDLGADSLDIAELVMELEDEFGTEIPDEEAEKINTVGDAVKFINSLEK
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_PSEA7
Sequence: MAIVKCKPTSAGRRFVVKVVNQELHKGAPYAPLLEKKSKSGGRNNNGRITTRHIGGGHKQHYRLVDFRRNKDGIPAIVERVEYDPNRTAHIALLKYADGERRYIIAPKGVAAGDQLISGIGAPIKAGNSMPLRNIPVGSTVHGIELKPGKGAQIARSAGASAQLVAREGAYVTLRLRSGEMRKVLAECRATLGEVSNSEHSLRSLGKAGATRWRGVRPTVRGVAMNPVDHPHGGGEGRTSAGRHPVSPWGLQTKGKKTRSNKRTDNMIVRRRK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: SOK1_YEAST
Sequence: MDQPRTHSGPTTASNPAPSSTNSSSAPSATNSKQERSSSSLSKPSSVVPSKDSPDGDAIAKTQAAALKNDMKSGDTSTLDGSSQNIIPNRASMQKYIDQSSDLLSRSSGVITPSMSLNASTNATNNDSSGNSANSSDLKIPIDRDNTIFKTFDTKTGQFLKNDDNEEEIRRNNKVDSIPPKNIYTNINNPSPSPPPSSKQPPSASAPQLPPATEPHKEQAAQQQPPGNASNFLRIFSNKKMRSHSVPTILHSSLRKLSSHNQYYRNQNILLNHPTPSGISKKKFSRNHHQPYLHSNNPLSSNPLSLKRAIFLNQQISGNASTNANNDNINNSTATSMTNQSFLSSSNFDLTLEDRINYIKATPTPVPFPPINLQGLKEIDLQEILKNPQLRHDIIFDPLLQFRPNLDGERGNKKRQLANIYWNDVQNEIYVYSKRPEIFQYNRSRLVPLFDTLRDVLLTIVPQKESPMINNVLDTELNIQELLKGSLIMSNLSGWLADLFKHHCAPMRDPWVDKMSNKFKEAERDSSLTRLIEGLRLVFQILETMKLDIANHQIRILRPALLSNAVEFEKQYFNTLIASKRVNLNTSLLWFDKKFNENVTAGLVRNPSSITIPDVYNICIRSIINLLSCRKMVREYPTPLSFDHARLILLRADIRQIVCILVCRLLFQQLVANDPSMDKATKEYVIHTYSTKRLKNEIISIITDEHGNCRWTKNTMSIAVHLCKVIDDLHREYDNNGSCEQARRPQLPSLDNSKITFAKSWLSKQTQPLSEVYGVLENRVFKSLEDAIFNRSECTIDGRVKQDFVYLYNTNNGNVGSTNTLSTTTDTASVKISPSLMSPSKTSTTTPTGNAIASRGLFAATELEEFENVYRHLYALINLHWSVFGPHYIEMLGDKVNKKGI
What is the function of this protein?
High copy suppressor of a cyclic AMP-dependent protein kinase mutant.
What are the official names of this protein?
Protein SOK1.
What is the protein family that this protein belongs to?
Belongs to the TCP11 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HISX_METMP
Sequence: MIVKKISKLNEKELDIILNRNKTNISGILPTVSEILENVQKNGDNALKEYTKKFDGVDIDNFKVSTEEIDKAYDKIDSKVVESLEKAYENIREFHEIQFKNLNEWEIDKKGIKAGQIIRPVEKAGCYVPGGRAFYPSTVLMTVTPAKVAGVKEVIVTSPPNGTEGNPATLVASDIAKADGIYKIGGAQAIGALAYGTKSIPKVDIIVGPGNIFVTAAKKLVYGEVSIDFPAGPSEVLIMCDESSNEEYVAMDFLAQAEHDPNASCIITVTSEKKAEKIKERILMEIKTAKRTEIIEKSILNSAIVIGSIDECIELSNSYAPEHLEIMTKNPREVLKSIENAGSIFLGNYAPVPVGDYASGTNHVLPTSACAKMYSGLSVETFIKKPTVQELTKEGLLGISDIVTTLAEAEGLFNHSEAVKRRLN
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: ALAA_MYCTU
Sequence: MDNDGTIVDVTTHQLPWHTASHQRQRAFAQSAKLQDVLYEIRGPVHQHAARLEAEGHRILKLNIGNPAPFGFEAPDVIMRDIIQALPYAQGYSDSQGILSARRAVVTRYELVPGFPRFDVDDVYLGNGVSELITMTLQALLDNGDQVLIPSPDYPLWTASTSLAGGTPVHYLCDETQGWQPDIADLESKITERTKALVVINPNNPTGAVYSCEILTQMVDLARKHQLLLLADEIYDKILYDDAKHISLASIAPDMLCLTFNGLSKAYRVAGYRAGWLAITGPKEHASSFIEGIGLLANMRLCPNVPAQHAIQVALGGHQSIEDLVLPGGRLLEQRDIAWTKLNEIPGVSCVKPAGALYAFPRLDPEVYDIDDDEQLVLDLLLSEKILVTQGTGFNWPAPDHLRLVTLPWSRDLAAAIERLGNFLVSYRQ
What are the official names of this protein?
Alanine aminotransferase, Alanine transaminase, Transaminase A.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_RHOPS
Sequence: MAKAANIIKVEQIGSAIRRHHSQRATLVGLKLNKIGRVTELQDTPEVRGMIAKVQHLVRVVDEK
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: DUSC_SHIFL
Sequence: MRVLLAPMEGVLDSLVRELLTEVNDYDLCITEFVRVVDQLLPVKVFHRICPELQNASRTPSGTLVRVQLLGQFPQWLAENAARAVELGFWGVDLNCGCPSKTVNGSGGGATLLKDPELIYQGAKAMREAVPAHLPVSVKVRLGWDSGEKKFEIADAVQQAGATELVVHGRTKEQGYRAEHIDWQAIGEIRQRLNIPVIANGEIWDWQSAQQCMAISGCDAVMIGRGALNIPNLSRVVKYNEPRMPWPEVVALLQKYTRLEKQGDTGLYHVARIKQWLSYLRKEYDEATELFQHVRVLNNSPDIARAIQAIDIEKL
What is the function of this protein?
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.  Specifically modifies U16 in tRNAs.
What are the official names of this protein?
tRNA-dihydrouridine(16) synthase, U16-specific dihydrouridine synthase, U16-specific Dus, tRNA-dihydrouridine synthase C.
What is the protein family that this protein belongs to?
Belongs to the Dus family. DusC subfamily.
Protein: S20AA_XENLA
Sequence: MESTTAFSAVTSALGTLDVHIMAPYLWMLVLGFVIAFVLAFSVGANDVANSFGTAVGSGVVTLRQACILASIFETVGSVLLGAKVSETIRKGLIDVTMYNSTQELLMAGSISAMFGSAVWQLAASFMKLPISGTHCIVGATIGFSLVAKGQQGVKWIELLRIVLSWFISPLLSGIMSALLFLFVRMFILRKADPVPNGLRALPVFYACTIGINLFSIMFTGAPLLGFDKVPLWGIILISVGCAVLCALIVWFVVCPRMKRKIECEFKSSPSESPLMDKKNQELRCPILKPDPEDLKLPVDGGIVAEVKVPILDMVSVSRTEERTVTFKMGECDDPIEKEKLNSMETNIDQPTNGSVQLPNGNHVQFSQAVSNQMNSSGQYQYHTVHKDSGLYKDLLHKLHLAKMGDCMGDSGDKPLRRNNSYTSYTMAICGMPLDSLRNRDTEARPDEAEKSTVHGADGKKRIRMDSYTSYCNAVADTHMDVEAEEQEEGSVEDVETDRKSSSSSLEERHDQDKPEVSLLFQFLQILTACFGSFAHGGNDVSNAIGPLVALYLVYETGDVTTKAATPIWLLLYGGIGICIGLWVWGRRVIQTMGKDLTPITPSSGFSIELASALTVVIASNVGLPISTTHCKVGSVVSVGWLRSKKAVDWRLFRNIFLAWFVTVPISGLISAGIMALFKYAILKV
What is the function of this protein?
Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport.
What are the official names of this protein?
Sodium-dependent phosphate transporter 1-A, Solute carrier family 20 member 1-A.
What is the protein family that this protein belongs to?
Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL20_ECOLI
Sequence: MARVKRGVIARARHKKILKQAKGYYGARSRVYRVAFQAVIKAGQYAYRDRRQRKRQFRQLWIARINAAARQNGISYSKFINGLKKASVEIDRKILADIAVFDKVAFTALVEKAKAALA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds close to the 5'-end of the 23S rRNA.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L20, Large ribosomal subunit protein bL20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: ATPF2_BARQU
Sequence: MTDTFWAFVGLVLFLALLAYFKVPEMIVHRLDARAKRIKDELDEALRLREEAQEVLAEYQRKHAEAEKDAQEIIAAAKREVEAVVSEARTKAEEYVKNRNKLAEQKIAQAEADAIRVVSSSAVDLAVSAARVLIEQELDSNKANELIKESLFEESLTKMKAYLN
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b 2, ATP synthase F(0) sector subunit b 2, ATPase subunit I 2, F-type ATPase subunit b 2, F-ATPase subunit b 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: NHAP2_PSEF5
Sequence: MNATTINSLFLIGALLVGASILVSSLSSRLGIPILVIILAVGMTAGVDGGGIIFDNYPTAYLVGNLALAVILLDGGLRTRVASFRVALWPALSLATVGVLITTGLTGMAAAWLFDLNLIQGLLIGAIVGSTDAAAVFSLLGGKGLNERVTASLEIESGSNDPMAVFLTVTLIDMLASGHTGLHWSLLTDLIREFGIGAVIGLGGGWLMLQLVNRIHLATGLYPILVVAGGLVVFALTNALHGSGFLAVYLCGLVIGNRPVRSRHGILHMLDGMAWLAQIGMFLVLGLLVTPHDLLPIALPALGLALWMILFARPLSVLVGLAPFKAFHGREKAFISWVGLRGAVPIILAVFPLMAGLPNAQLYFNLAFFIVLISLLVQGTSLPWVAKWLKVTVPPEPAPISRAALEVHVTSEWELFVYRLGAEKWCIGAALRELKMPEGTRIAALFRGQQLLHPSGSTVLEADDLLCVIGHEHNLPALGKLFSQAPERGLDLRFFGDFVLEGDAQLGAVSALYGLKLDGQDADMPLGAFIAQKVGGAPVVGDQVEWNNTIWTVAVMDGNKIGKVGVRFPEGSRPGPGLFL
What is the function of this protein?
K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.
What are the official names of this protein?
K(+)/H(+) antiporter NhaP2, Potassium/proton antiporter NhaP2.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PABP_KLULA
Sequence: MSDITEKTAEQLENLQINDDQQPAQSASAPSTSASESEASSVSKVENNNASLYVGELDPNITEALLYDVFSPLGPISSIRVCRDAVTKASLGYAYVNYTDYEAGKKAIQELNYAEINGRPCRIMWSERDPAIRKKGSGNIFIKNLHPAIDNKALHETFSTFGEVLSCKVALDENGNSRGFGFVHFKEESDAKDAIEAVNGMLMNGLEVYVAMHVPKKDRISKLEEAKANFTNIYVKNIDVETTDEEFEQLFSQYGEIVSAALEKDAEGKPKGFGFVNFVDHNAAAKAVEELNGKEFKSQALYVGRAQKKYERAEELKKQYEQYRLEKLAKFQGVNLFIKNLDDSIDDEKLKEEFAPYGTITSARVMRDQEGNSKGFGFVCFSSPEEATKAMTEKNQQIVAGKPLYVAIAQRKDVRRSQLAQQIQARNQIRFQQQQQQQAAAAAAGMPGQYMPQMFYGVMAPRGFPGPNPGMNGPMGAGIPKNGMVPPPQQFAGRPNGPMYQGMPPQNQFPRHQQQHYIQQQKQRQALGEQLYKKVSAKIDDENAAGKITGMILDLPPQQVIQLLDNDEQFEQQFQEALAAYENFKKEQEAQA
What is the function of this protein?
Binds the poly(A) tail of mRNA.  Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation.  In the nucleus, involved in both mRNA cleavage and polyadenylation.  Is also required for efficient mRNA export to the cytoplasm.  Acts in concert with a poly(A)-specific nuclease (PAN) to affect poly(A) tail shortening, which may occur concomitantly with either nucleocytoplasmic mRNA transport or translational initiation.  In the cytoplasm, stimulates translation initiation and regulates mRNA decay through translation termination-coupled poly(A) shortening, probably mediated by PAN (By similarity).
What are the official names of this protein?
Polyadenylate-binding protein, cytoplasmic and nuclear, PABP, Poly(A)-binding protein, Polyadenylate tail-binding protein.
What is the protein family that this protein belongs to?
Belongs to the polyadenylate-binding protein type-1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL7_PARUW
Sequence: MSKKKTEELVDALSELTVLEMAELKTLLEDKWGVKAAAPVAVAAPAAGAPAAAVVESTDFQVTLTEAPADKKIGIIKVVREITGLGLKEAKDLVEAAPKELKPTAPKAEAEDIKKKIETAGGKVTLKGL
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: OPRD_MOUSE
Sequence: MELVPSARAELQSSPLVNLSDAFPSAFPSAGANASGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTQPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRTPCGRQEPGSLRRPRQATTRERVTACTPSDGPGGGAAA
What is the function of this protein?
G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids.  Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase.  Signaling leads to the inhibition of adenylate cyclase activity.  Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance.  Plays a role in the perception of pain and in opiate-mediated analgesia.  Plays a role in developing analgesic tolerance to morphine.
What are the official names of this protein?
Delta-type opioid receptor, D-OR-1, DOR-1, K56, MSL-2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TATA_NEIM0
Sequence: MGSFSLTHWIIVLIIVVLIFGTKKLRNVGKDLGGAVHDFKQGLNEGTDGKEAQKDDVIEHKKDEDKA
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PFDA_METHJ
Sequence: MAAPVDPREVQSLQTYLNQYTQQAEVYSRQLGMMEEGIREANASIETLKALAEAGEAPVFMPIGGGLNIRATIIQPDEVFVSIGSDIIVQKTNEGAISYLQDRIKEMEATAKNLTEVLQKIDAQVKDIQKRLEQLYRQAQAEQQGAGSL
What is the function of this protein?
Molecular chaperone capable of stabilizing a range of proteins.  Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
What are the official names of this protein?
Prefoldin subunit alpha, GimC subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit alpha family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU1M_DIDVI
Sequence: MFLINLLMYIIPILLAVAFLTLVERKVLGYMQFRKGPNVIGPYGILQPFADALKLFIKEPLRPMTSSISMFTIAPTLALTLAFTIWTPLPMPNALLDLNLGLLFILALSGLSVYSILWSGWASNSKYALIGALRAVAQTISYEVTLAIILLSIMLINGSFTLKNMLITQENMWLIMMTWPLTMMWYISTLAETNRAPFDLTEGESELVSGFNVEYAAGPFAMFFLAEYANIMVMNAITATLFLGSPLSSNIPYINSMTFMMKMLILTTTFLWIRASYPRFRYDQLMYLLWKNFLPITLALCLWYISIPISLSSLPPQL
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CYSG_RUTMC
Sequence: MNYLPIFIDIKQKPCLVVGGGDIAYRKINFLLKAHGQVTCIAKSSCKNVVKLASDNKIIYFEKSFEASDIKEQVLIVSATDNTSLNKQVSELSNQNNIPVNVVDSPDLCTFIMPSIVDRSPIVIAISSAGKAPVLARLIRAKLESTLPHAYGKLAELAGNFRDKVKEKFSNIEDRRYFWEKTFSGIIAEKVFSGKIQEAKADLQVQLDGSTKTQVGEVYLVGGGPGDPDLLTFKALRLMQQADVVLYDRLVSNGVMGLVRRDAQLIYVGKERDNHVVPQGDINQLLVNLAKQGRRVCRLKGGDPFIFGRGGEEIETLAENGISFQVVPGITAASGCSTYSGIPLTHRDYSQSCRFVTGHLKDGSMNLPWHELSVEQQTIVFYMALNGARHLSEQLITHGMSPDMPVALVEKGTTPEQKVYTTTLKKLPDLVKNEIIHAPTLIIIGEVVTLREKLNWFDAKLASSKKSYLFGG
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: Y7331_DICDI
Sequence: MIPNNINNRKKLKLPELFKEKYGFNKKGIELRYCDGEKGMGIFSNRKFNKGEKIMKIEPYVWSVAKHAIVCDECLKNKLDLEEGKTLKRCSNCKLVYYCSTDCQTKAWKIHKQECKILSTIPSTTDKKNINTKSTTMLLRLFIKRNLELINNNNNNNNNNNNNNNNNDNHITGQYEIIDGLLNHKDIRSDNNEYKSFSSGFCSLLGEDPQLKAPIVLEYLLKLEPNCITIPRCEASSIGLYPLMLFFNHSCKPNISIINNRKELLIITNKIIEKDEELFINYSPAICYRNERLDNLKQCFFFNCKCTLCLGEEKIKSKDLYITCNINNCGGRINQEIDININNNNNNNNNNNNNSNNNNNNNNSNEEILKCYKCLKVYKGQEKDEILKKKLIIKNLQNKLSTNTDQININQEFKSLLELYCKEIHPTDPLFYEIVNKTQLFYLGNNNKFISDNELSTIYHPRYQIMIKYHLLQVQNLEYEYCRQMLDYVNTLATTSYFKDALNILTDLMSNHLSQIDFYGFNRDELLSLLYNLQHEYKNNIKTSRKIIN
What is the function of this protein?
Probable methyltransferase.
What are the official names of this protein?
SET and MYND domain-containing protein DDB_G0277331.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily.
Protein: RLUD_SALTY
Sequence: MAQRVQLTATVSENQLGQRLDQALAEMFPDYSRSRIKEWILNQRVLVNGQLCDKPKEKVLGGERVAIDAEIDEEIRFEAQDIPLDIVYEDDDILVINKPRDLVVHPGAGNPDGTVLNALLHYYPPIADVPRAGIVHRLDKDTTGLMVVAKTVPAQTRLVESLQLREITREYEAVAIGHMTAGGTVNEPISRHPTKRTHMSVHPMGKPAVTHYRIMEHFRVHTRLRLRLETGRTHQIRVHMAHITHPLVGDQVYGGRPRPPKGASEEFISTLRKFDRQALHATMLRLYHPVSGIEMEWHAPIPQDMVDLIDAMRADFEDHKDDVDWL
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA.
What are the official names of this protein?
Ribosomal large subunit pseudouridine synthase D, 23S rRNA pseudouridine(1911/1915/1917) synthase, rRNA pseudouridylate synthase D, rRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RluA family.
Protein: CCF32_ORYSJ
Sequence: MARPRTRSVARMEATAAAAAAAEEEEAGNPDGAEGAAVVAVAPEAAAEGPNEPNAGEASREPDAGQASREPDVAGPSRQPGAAGPSREPGAAGGPRQPGAAGGPWQLVPNAAGPAVAPYVEDIDRYLRSLEGREMAKCLDAVQFCTAEESRRPIVNYDQEIQGGHINMRGKLVNWMEELVYGFNLWDNILYLAVSYVDRFLSRNVVNRERLQLLGTSALFVASKYEDRCHPSARFFSSITADTYTTQQVVAMEANILSFLNFQMGSPTVITFLRRFLFSCRGSNRPINIRLELMCIYLAELSLLDDYNIRFLPSIVAAACLFVGKFTLNPNTRPWNLSVQRITGYKVSDIEDCIRSIHDLQAGRKWSNLRAIRSKYEDDAFERVSTIPSPNTIKPSFLRDLKYVNG
What are the official names of this protein?
Putative cyclin-F3-2, CycF3;2.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin F subfamily.
Protein: GLYC_LYCVW
Sequence: MGQIVTMFEALPHIIDEVINIVIIVLIIITSIKAVYNFATCGILALVSFLFLAGRSCGMYGLNGPDIYKGVYQFKSVEFDMSHLNLTMPNACSVNNSHHYISMGSSGLEPTFTNDSILNHNFCNLTSALNKKSFDHTLMSIVSSLHLSIRGNSNYKAVSCDFNNGITIQYNLSSSDPQSAMSQCRTFRGRVLDMFRTAFGGKYMRSGWGWTGSDGKTTWCSQTSYQYLIIQNRTWENHCRYAGPFGMSRILFAQEKTKFLTRRLSGTFTWTLSDSSGVENPGGYCLTKWMILAAELKCFGNTAVAKCNVNHDEEFCDMLRLIDYNKAALSKFKQDVESALHVFKTTLNSLISDQLLMRNHLRDLMGVPYCNYSKFWYLEHAKTGETSVPKCWLVTNGSYLNETHFSDQIEQEADNMITEMLRKDYIKRQGSTPLALMDLLMFSTSAYLISIFLHFVRIPTHRHIKGGSCPKPHRLTNKGICSCGAFKVPGVKTIWKRR
What is the function of this protein?
Forms the virion spikes together with glycoprotein G1.  The glycoprotein spike trimers are connected to the underlying matrix.  Class I viral fusion protein that directs fusion of viral and host endosomal membranes, leading to delivery of the nucleocapsid into the cytoplasm.  Membrane fusion is mediated by irreversible conformational changes induced by acidification.
What are the official names of this protein?
Pre-glycoprotein polyprotein GP complex, Pre-GP-C.
What is the protein family that this protein belongs to?
Belongs to the arenaviridae GPC protein family.
What are the subcellular locations of this protein?
[Glycoprotein G1]: Virion membrane; Peripheral membrane protein. Host endoplasmic reticulum membrane; Peripheral membrane protein. Host Golgi apparatus membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. SUBCELLULAR LOCATION: [Glycoprotein G2]: Virion membrane; Single-pass membrane protein. Host endoplasmic reticulum membrane; Single-pass membrane protein. Host Golgi apparatus membrane; Single-pass membrane protein. Host cell membrane; Single-pass membrane protein. Note=Binding to the stable signal peptide masks endogenous ER localization signals in the cytoplasmic domain of G2 to ensure that only the fully assembled, tripartite GP complex is transported for virion assembly. SUBCELLULAR LOCATION: [Stable signal peptide]: Virion membrane; Multi-pass membrane protein. Host endoplasmic reticulum membrane; Multi-pass membrane protein. Host Golgi apparatus membrane; Multi-pass membrane protein. Host cell membrane; Multi-pass membrane protein.