PharMolix/UniProtQA huggingface dataset:
Protein: LRC19_HUMAN
Sequence: MKVTGITILFWPLSMILLSDKIQSSKREVQCNFTEKNYTLIPADIKKDVTILDLSYNQITLNGTDTRVLQTYFLLTELYLIENKVTILHNNGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIEQLNADVFVPLRSLKLLNLQGNLISYLDVPPLFHLELITLYGNLWNCSCSLFNLQNWLNTSNVTLENENITMCSYPNSLQSYNIKTVPHKAECHSKFPSSVTEDLYIHFQPISNSIFNSSSNNLTRNSEHEPLGKSWAFLVGVVVTVLTTSLLIFIAIKCPIWYNILLSYNHHRLEEHEAETYEDGFTGNPSSLSQIPETNSEETTVIFEQLHSFVVDDDGFIEDKYIDIHELCEEN
What is the function of this protein?
Pathogen-recognition receptor which mediates the activation of TRAF2- and TRAF6 NF-kappa-B signaling pathways and induces the expression of pro-inflammatory cytokines (PubMed:19679103, PubMed:25026888).  In kidney, prevents infection by uropathogenic bacteria by inducing the production of cytokines, chemokines and antimicrobial substances.  In gut, involved in host-microbiota interactions, plays a critical role in promoting the recruitment of immune cells and intestinal inflammation (By similarity).
What are the official names of this protein?
Leucine-rich repeat-containing protein 19.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: 3S11_AIPLA
Sequence: LTCCNQQSSQPKTTTDCADNSCYKKTWQDHRGTRIERGCGCPQVKPGIKLECCKTNECNN
What is the function of this protein?
Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.
What are the official names of this protein?
Short neurotoxin A.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type I alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: THIE_NATPD
Sequence: MTQDFGVYLVTGAEHSAGRSTAEVVEAAIRGGVDIVQLRDKTATARERYEVGTELRTLTRDAGVPLVVNDRLDLAAAIDADGVHLGDDDLPIEVAREQLGSDAIVGRSVSTPDAAREAEQAGADYLGVGAIYGTDSKDTDPEQSNIGLDRIRAVRDATSLPFVGIGGVTPDNAAPVVEAGADGVAVISAITAADDPEHATRRLADAVEGVAPNV
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: FLHD_ECO27
Sequence: MHTSELLKHIYDINLSYLLLAQRLIVQDKASAMFRLGINEEMATTLAALTLPQMVKLAETNQLVCHFRFDSHQTITQLTQDSRVDDLQQIHTGIMLSTRLLNDVNQPEEALRKKRA
What is the function of this protein?
Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region.  Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes.  Also regulates genes whose products function in a variety of physiological pathways.
What are the official names of this protein?
Flagellar transcriptional regulator FlhD.
What is the protein family that this protein belongs to?
Belongs to the FlhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_SALAR
Sequence: MANIKSAKKRAVQSEKARKHNASRRSMMRTFIKKVYAAIEAGDKAAALKAFNEMQPIVDRQAAKGLIHKNKAARHKANLTAQINKLA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: YG37_YEAST
Sequence: MCILMATRAHPDYELILISNRDEFLARKTHATCWHNNDFILSPYDLAKTSAEKQIFGTWSGINKEGKLATILNLKLDNEQNNTKSRSRGLLPFIFLSIHKADFEDWDNYKKFEGHYDGLKSTGDFNFFYGDVIKKQYKVIDSLGRTFDVLSSTCRKDLDSYMVVSNGKFYDSSSIPGQAWEKVKVARDSLENLVLENIESDEEKIISSCFQLASKSSLPSTISNPDVLQMVDPNVTMNTIYVPPLRRPPRDDLGASIPDGDYYGTRSQIVLLVSKDSTRVTFIERVLYSSDEDVRKYSVTSPKEEKRFKFKL
What are the official names of this protein?
Uncharacterized protein YGR127W.
Protein: 054L_IIV3
Sequence: MASEATVESVETKVESPIVESPVDQGLLESIKNFMDDLAVVTENENFQDYHTIVRRIDETKVKSYNKLVGGFREFFSLNKTALMEGNFEGLIEPHISYKTESGSFFFNFQTTYLETDEANQEIIKEHLNHIWAQIRSENKCPEQLYIDEIFQKLKNKDQLTMDDQLIRDLFTKFQTANFNVTALIRAGCSKAREFLTNNGSQKSSSTFRLIETIENVNVDNFTQMDFMALISKISAIFSESGESNPLNLCLSSLFGGGNTNQPSLTSMFPFPTPPLPDNVLLDNLDQLTLEQQSETTGDDDHHSFEPEK
What are the official names of this protein?
Uncharacterized protein 054L.
Protein: ARNE_ECO8A
Sequence: MIWLTLVFASLLSVAGQLCQKQATCFVAINKRRKHIVLWLGLALACLGLAMVLWLLVLQNVPVGIAYPMLSLNFVWVTLAAVKLWHEPVSPRHWCGVAFIIGGIVILGSTV
What is the function of this protein?
Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
What are the official names of this protein?
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE, L-Ara4N-phosphoundecaprenol flippase subunit ArnE, Undecaprenyl phosphate-aminoarabinose flippase subunit ArnE.
What is the protein family that this protein belongs to?
Belongs to the ArnE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PE35_MYCTU
Sequence: MEKMSHDPIAADIGTQVSDNALHGVTAGSTALTSVTGLVPAGADEVSAQAATAFTSEGIQLLASNASAQDQLHRAGEAVQDVARTYSQIDDGAAGVFAE
What is the function of this protein?
Plays a major role in RD1-associated pathogenesis, and may contribute to the establishment and maintenance of M. tuberculosis infection.  Together with PPE68, stimulates the secretion of IL-10 and MCP-1 from human macrophages, via the interaction with human Toll-like receptor 2 (TLR2).
What are the official names of this protein?
PE family immunomodulator PE35.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PE family.
What are the subcellular locations of this protein?
Secreted. Cell surface.
Protein: ASTD_BURTA
Sequence: MTELFIDGAWVDGAGPVFASRNPGTNERVWEGASASADDVERAVASARRAFAAWSALDLDARCTIVKRFAALLVERKEALATMIGRETGKPLWEARTEVASMAAKVDISITAYHERTGEKRAPMADGVAVLRHRPHGVVAVFGPYNFPGHLPNGHIVPALIAGNTVVFKPSELAPGVARATVEIWRDAGLPAGVLNLVQGEKDTGVALANHRQIDGLFFTGSSDTGTLLHKQFGGRPEIVLALEMGGNNPLVVAEVEDIDAAVHHAIQSAFLSAGQRCTCARRILVPRGAFGDRFVARLADVASKITASVFDADPQPFMGAVISARAASRLVAAQARLVGLGASPIIEMKQRDPALGFVNAAILDVTNVRELPDEEHFGPLAQIVRYTDLDDAIARANDTAFGLSAGLLADDEQAWHTFRRAIRAGIVNWNRPTNGASSAAPFGGAGRSGNHRPSAYYAADYCAYPMASVESAQLQMPASLSPGLHF
What is the function of this protein?
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
What are the official names of this protein?
N-succinylglutamate 5-semialdehyde dehydrogenase, Succinylglutamic semialdehyde dehydrogenase, SGSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. AstD subfamily.
Protein: YP32_SCHPO
Sequence: MDKNLEEKVIWLVRHAQAEHNVGPPGNHRRINQVGIKQWEALHNWLVDNPIPIDVIVCSPLRRTLQTMEISFKSYIHKELPVPIKISPLFEESGNWPCDCAMDLSSTEKLFPDYDFSSCYDDIYPLRRGLYGTTYDENYCRAQKPLKHLASLHEKNIVVVTHSVYLRFLLREQRPEDNMNFMPPEKVFRNCEIRKYNLCHTGFQWELIPLIDN
What are the official names of this protein?
Probable phosphatase SPBPB21E7.02c.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: PIF1_SCHPO
Sequence: MFSCQSLYKFSHSFRKRIPVMFQRAQQKSSLLHTQNESSHQPSLNKLGGFSSASLNFNSSRSSTNDDQQTFSSQSDNLPSSPITLPAKRGRSAASLKQLDNTVGFDVSKPSLPVFENSGLGSKYSTEIANGVYIDENDFDDDLLLENDIDQKPIPWSSSPIEHTKLTKSMLSSEKRSKNHLSKIYEDHTSEKGASSVISSNITRQGIKRSRTLPWAVDPYRYGDPDPKRTSTSADISQHTVSNDSSNKLSNGRSSSLDSLAKKRMSKSKSTPQISKKFSVPLNSASKSPIGSSLFKTSDSRKKSVPSIFLSDEQKRILDMVVEQQHSIFFTGSAGTGKSVLLRKIIEVLKSKYRKQSDRVAVTASTGLAACNIGGVTLHSFAGVGLARESVDLLVSKIKKNKKCVNRWLRTRVLIIDEVSMVDAELMDKLEEVARVIRKDSKPFGGIQLVLTGDFFQLPPVPENGKESKFCFESQTWKSALDFTIGLTHVFRQKDEEFVKMLNELRLGKLSDESVRKFKVLNRTIEYEDGLLPTELFPTRYEVERSNDMRMQQINQNPVTFTAIDSGTVRDKEFRDRLLQGCMAPATLVLKVNAQVMLIKNIDDQLVNGSLGKVIGFIDDETYQMEKKDAEMQGRNAFEYDSLDISPFDLPDVKQKKYKLIAMRKASSTAIKWPLVRFKLPNGGERTIVVQRETWNIELPNGEVQASRSQIPLILAYAISIHKAQGQTLDRVKVDLGRVFEKGQAYVALSRATTQEGLQVLNFSPAKVMAHPKVVQFYKQLASVNGLPIRNENKAPVQMRGVKNK
What is the function of this protein?
DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.  Involved in the maintenance of mitochondrial (mtDNA).  Required for both repair of mitochondrial DNA and recognition of a recombinogenic signal characterized by a 26-bp palindromic at sequence in the ery region of mitochondrial DNA.  May have a general role in chromosomal replication by affecting Okazaki fragment maturation.  Required for the completion of S-phase.
What are the official names of this protein?
ATP-dependent DNA helicase pfh1, DNA repair and recombination helicase pfh1, PIF1 helicase homolog, RRM3/PIF1 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the helicase family. PIF1 subfamily.
What are the subcellular locations of this protein?
[Isoform Nuclear]: Nucleus, nucleolus. Note=Mainly concentrated in the nucleolus, and occasionally redistributes to single nuclear foci outside the nucleolus, probably sites of DNA repair. SUBCELLULAR LOCATION: [Isoform Mitochondrial]: Mitochondrion.
Protein: EXL2_ARATH
Sequence: MKRNSINIHHVTSFSSSPFWCVFFLVLLCKTSTNALVKQPPNETTPAIIVFGDSIVDAGNNDDIMTTLARCNYPPYGIDFDGGIPTGRFCNGKVATDFIAGKFGIKPSIPAYRNPNLKPEDLLTGVTFASGGAGYVPFTTQLSTYLFIYKPLLFLKGGIALSQQLKLFEEYVEKMKKMVGEERTKLIIKNSLFMVICGSNDITNTYFGLPSVQQQYDVASFTTLMADNARSFAQKLHEYGARRIQVFGAPPVGCVPSQRTLAGGPTRNCVVRFNDATKLYNVKLAANLGSLSRTLGDKTIIYVDIYDSLLDIILDPRQYGFKVVDKGCCGTGLIEVALLCNNFAADVCPNRDEYVFWDSFHPTEKTYRIMATKYFERYV
What are the official names of this protein?
GDSL esterase/lipase EXL2, Family II extracellular lipase 2, Family II lipase EXL2.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family.
What are the subcellular locations of this protein?
Secreted.
Protein: GATA_PROMM
Sequence: MAIAEWRQQLKLGEVSARELTDHQLARIAVVDPTLHAFLDITADRARADADRIDEALAAGESLPPLAGVPLAIKDNLCTKGIRTTCSSRMLETFVPPYESTVTERLWQAGAVLLGKTNLDEFAMGSSTETSAFGATSNPWDISRVPGGSSGGSAAAVAAGECMAALGSDTGGSIRQPASFCGVVGLKPTYGRVSRWGLVAFASSLDQVGPFTTNVADAAELLQVIAGSDPRDSTCLNVAVPDYCSALSQPMSGVRIGLIRECFDQNGLDAQVKRTVLTAAEKLQSLGAELVEVSCPRFSDGIATYYVIAPSEASANLARYDGVKYGYRAEGADALAAMTARSRAEGFGSEVQRRILIGTYALSAGYMDAYYKKAQQVRTLIRQDFDAAFQTVDVLLTPTSPTTAFKAGAHADDPLAMYLADLLTIPANLAGLPAISLPCGFDDDGLPIGVQLIANVLEESRLLQVAFHYEQAANVMANHPQGNFIP
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: LDH2_STAA3
Sequence: MKTFGKKVVLIGDGSVGSSYAFAMVTQGVADEFVIIDIAKDKVKADVQDLNHGTVHSPSPVDVKAGEYEDCKDADLVVITAGAPQKPGETRLQLVEKNTKIMKSIVKSVMDSGFDGYFLIAANPVDILTRFVKEYTGLPAERVIGSGTVLDSARLQYLISQELGVAPSSVDASIIGEHGDTELAVWSQANVAGISVYDTLKEQTGSEAKAEEIYVNTRDAAYEIIQAKGSTYYGIALALMRISKAILNNENNVLNVSIQLDGQYGGHKGVYLGVPTLVNQHGAVKIYEMPLSAEEQALFDKSVKTLEDTFDSIKYLLED
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate (Potential).  Contributes to S. aureus growth during nitrosative stress in both aerobically and anaerobically cultured cells, despite playing a secondary role in this resistance mechanism (By similarity).
What are the official names of this protein?
L-lactate dehydrogenase 2, L-LDH 2.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSP4_STRMT
Sequence: MKNTVNLDKFVELKEKDLQNIQGGEIRQTHNIFFNFFKRR
What is the function of this protein?
Acts as a pheromone, induces cells to develop competence for genetic transformation.
What are the official names of this protein?
Competence-stimulating peptide, CSP.
What is the protein family that this protein belongs to?
Belongs to the ComC family.
What are the subcellular locations of this protein?
Secreted.
Protein: RIPP2_DANRE
Sequence: MENITFTSGLNSEMDANQPWRPWLSQTSRKAPDYKPYKRPADDEQHKLSIFKHPVKLFWPKSQCFDYLYEDAEVLLRNYPVQATICLYEDPDTEDEEDYSDEEDEKELR
What is the function of this protein?
Plays a role in somitogenesis.  Required for somite segregation and establishment of rostrocaudal polarity in somites (By similarity).
What are the official names of this protein?
Protein ripply2.
What is the protein family that this protein belongs to?
Belongs to the ripply family.
What are the subcellular locations of this protein?
Nucleus.
Protein: AHLLB_AGRFC
Sequence: MGNKLFVLDLGEIRVDENFIIANSTFVTPQKPTVSSRLIDIPVSAYLIQCTDATVLYDTGCHPECMGTNGRWPAQSQLNAPYIGASECNLPERLRQLGLSPDDISTVVLSHLHNDHAGCVEYFGKSRLIAHEDEFATAVRYFATGDHSSPYIVKDIEAWLATPRNWDLVGRDERERELAPGVNLLNFGTGHASGMLGLAVRLEKQPGFLLVSDACYTATNYGPPARRAGVLHDTIGYDRTVSHIRQYAESRSLTVLFGHDREQFASLIKSTDGFYE
What are the official names of this protein?
N-acyl homoserine lactonase AiiB, AHL-lactonase AiiB.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily.
Protein: Y3275_PSEAE
Sequence: MINYFWFVLAAFCEIAGCYAFYLWLRLGKSALWVLPGLLSLTLFALLLTRVEASYAGRAYAAYGGIYVAASLFWLAFVERSRPLWSDWLGVALCVVGASVVLFGPRLSQ
What are the official names of this protein?
UPF0060 membrane protein PA3275.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NRG2_ARATH
Sequence: MGCAASKLDNEDAVRRCKDRRRLMKEAVYARHHLAAAHADYCRSLRITGSALSSFASGEPLSVSDQTPAVFLHTPPPPLSEQSPAKFVPPRFSPSPAPSSVYPPSTSPSVASSKQPSVMSTSSNRRRKQQPKPRLPHILSESSPSSSPRSERSNFMPNLYPSAYQNSTYSATPSHASSVWNWENFYPPSPPDSEFFNRKAQEKKHNSDNRFNDEDTETVRSEYDFFDTRKQKQKQFESMRNQVEEETETEREEVQCSEWEDHDHYSTTSSSDAAEEEEEDDDRESISEVGTRSEFGSTVRSNSMRRHHQQPSPMPQVYGGAEQSKYDKADDATISSGSYRGGGDIADMKMVVRHRDLKEIIDAIKENFDKAAASGEQVSQMLELGRAELDRSFSQLKKTVIHSSSLLSNLSSTWTSKPPLAVKYRIDTTALDQPNSSKSLCSTLDRLLAWEKKLYEEIKAREGFKIEHEKKLSQLQSQEYKGEDEAKLDKTKASITRLQSLIIVTSQAVTTTSTAIIRLRDTDLVPQLVELCHGFMYMWKSMHQYHETQNSIVEQVRGLINRSGKGESTSELHRQATRDLESAVSSWHSSFSSLIKFQRDFIHSVHAWFKLTLLPVCQEDAANHHKEPLDAYAFCDEWKLALDRIPDTVASEAIKSFINVVHVISAKQADEHKIKKRTESASKELEKKASSVRNLERKYYQSYSMVGVGLPESGPDNQHMLDARDPLSDKKSELAVCQRRVEEEMVKYSKAIEVTRAMTLNNLQTGLPGVFQSLTSFSALFMESLQTVCTRSYSIK
What is the function of this protein?
Required for nitrate signaling.  Regulates expression of the nitrate-responsive genes NIA1, NIR1, NRT2. 1 and NPF6. 3/NRT1. 1.
What are the official names of this protein?
Nitrate regulatory gene2 protein, NRG2 protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS21_RICAE
Sequence: MILVNVHAGNCDNTLKNFKKKLQRELYFRKMKEQRYYETPSAKRVRKVQEAARRQRKFARKKMFDE
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: CCNO_MOUSE
Sequence: MVTPCPASPGSPAAGAGRRDSHQNLRAPVKKSRRPCLRRKKPLRPLNACSLPGDSGVCDLFESPSSSSDGADSPAVSAARDCSSLLNPAQPLTALDLQTFREYGQSCYDFRKAQENLFHPRESLARQPQVTAESRCKLLSWLLQVHRQFGLSFESLCLTVNTLDRFLLTTPVAADCFQLLGVTCLLIACKQVEVHPPRLKQLLALCGGAFSRQQLCNLECIVLHKLHFSLGAPTINFFLEHFTQWRMEAGQAEVTEALEAQTLARGVAELSLTDYAFTTYTPSLMAICCLALADGLLQHQHEMDLRLGEHPEATLQDCLGKLQTLVSINSSSLPRILPPQIWERCSLPQSWQ
What is the function of this protein?
Specifically required for generation of multiciliated cells, possibly by promoting a cell cycle state compatible with centriole amplification and maturation.  Acts downstream of MCIDAS to promote mother centriole amplification and maturation in preparation for apical docking (By similarity).  May be involved in apoptosis in lymphoid cells; however, this result requires additional evidences in vivo.  May be involved in oocyte meiotic resumption in oocytes.
What are the official names of this protein?
Cyclin-O.
What is the protein family that this protein belongs to?
Belongs to the cyclin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Note=Localizes to the apical part of cytoplasm.
Protein: CARG2_BPCA1
Sequence: MANFSFVSGAKFRPFSYQEMLQPLQAYTQEYNTIQEGMGELGTKADVFERMANEQTDPQAYAMYKQYSNDLAAQAESLAKQGLTPASRQGLIDMKRRYSSEIVPIEQAYKRRQELVDEQRKLQAQDSTLLFDRPASTLSLDELISNPALSPQSYSGALLSKQVGTAAQNLAKEVRENPRKWRTILGNQYYETIMQKGFRPEEIMQAVQNNPEASPILQGIVEDAVGSSGIRNWNDENILNRAYDYARQGLWNAVGETQYQTLSNKAYDYAMQERLAAAKKGKTEGTPSAVFRSVPKTKVDGDKKTTELNDELQFIQQLRANPSMINEEVERVNPGYPTQYGVNVGGGIYKVKPHAERLQQIIKKYDMKDGNMDQLEQKLQADIRSSAVRDFIYKPNITQSDLISQVIKENARTLGAATESTGLYELDDNRKGDPIKLKNISDYFTGDNDISYDPEVGLIINATKDGKTKSAVIDPELIDDADRSVAGYMNNINVLLENGYDVEAQRYINTMMNYIYGKFNTLAKRQSNTDSKLE
What is the function of this protein?
Protein that is stored in high quantity in the viral capsid and may play a role during ejection.
What are the official names of this protein?
Cargo protein 2, Gene product 46, gp46.
Protein: CBPA_ESCF3
Sequence: MELKDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEARFKEVAEAWEVLSDEQRRAEYDQMWQHRNDPQFNRQFHHGDGQSFNAEDFDDIFSSIFGQHARQARQRPATRGHDIEIEVPVFLEETLSEHKRTISYNLPVYNAFGMVEQEIPKTLNVKIPAGVGNGQRIRLKGQGTPGENGGPNGDLWLIIHIAPHPLFDVVGQDLEIVVPVAPWEAALGGKVTVPTLKESILLTIPAGSQAGQRLRVKGKGLVSKKHTGDLYAVLKIVMPPKPDENATALWQQLADAQSSFDPRKDWGKA
What is the function of this protein?
DNA-binding protein that preferentially recognizes a curved DNA sequence.  It is probably a functional analog of DnaJ; displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adaptive response to environmental stresses other than heat shock.  Lacks autonomous chaperone activity; binds native substrates and targets them for recognition by DnaK.  Its activity is inhibited by the binding of CbpM.
What are the official names of this protein?
Curved DNA-binding protein.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: ESPC_MYCTU
Sequence: MTENLTVQPERLGVLASHHDNAAVDASSGVEAAAGLGESVAITHGPYCSQFNDTLNVYLTAHNALGSSLHTAGVDLAKSLRIAAKIYSEADEAWRKAIDGLFT
What is the function of this protein?
Required for ESX-1 function.  Required for either stability or expression of EspA.
What are the official names of this protein?
ESX-1 secretion-associated protein EspC.
What is the protein family that this protein belongs to?
Belongs to the EspC family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the ESX-1 / type VII secretion system (T7SS).
Protein: GUN1_HYPJR
Sequence: MAPSVTLPLTTAILAIARLVAAQQPGTSTPEVHPKLTTYKCTKSGGCVAQDTSVVLDWNYRWMHDANYNSCTVNGGVNTTLCPDEATCGKNCFIEGVDYAASGVTTSGSSLTMNQYMPSSSGGYSSVSPRLYLLDSDGEYVMLKLNGQELSFDVDLSALPCGENGSLYLSQMDENGGANQYNTAGANYGSGYCDAQCPVQTWRNGTLNTSHQGFCCNEMDILEGNSRANALTPHSCTATACDSAGCGFNPYGSGYKSYYGPGDTVDTSKTFTIITQFNTDNGSPSGNLVSITRKYQQNGVDIPSAQPGGDTISSCPSASAYGGLATMGKALSSGMVLVFSIWNDNSQYMNWLDSGNAGPCSSTEGNPSNILANNPNTHVVFSNIRWGDIGSTTNSTAPPPPPASSTTFSTTRRSSTTSSSPSCTQTHWGQCGGIGYSGCKTCTSGTTCQYSNDYYSQCL
What is the function of this protein?
Endoglucanase (EG) that cleaves the internal beta-1,4-glucosidic bonds in cellulose.  The degradation of cellulose involves an interplay between different cellulolytic enzymes.  Hydrolysis starts with EGs, which cut internal glycosidic linkages to reduce the polymerization degree of the substrate and creates new chain ends for exocellobiohydrolases (CBHs).  The CBH release the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain.  Finally, beta-1,4-glucosidases hydrolyze the cellobiose and other short cello-oligosaccharides into glucose units.
What are the official names of this protein?
Endoglucanase EG-1, Cellulase, Endo-1,4-beta-glucanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 7 (cellulase C) family.
What are the subcellular locations of this protein?
Secreted.
Protein: SRC2_XENLA
Sequence: MGATKSKPREGGPRSRSLDIAEGSHQPFTSLSASQTPSKSLDSHRPSGQPFGGNCDLTPFGGVNFSDTITSPQRTGPLAGGVTTFVALYDYESRTETDLSFRKGERLQIVNNTEGDWWLARSLSSGQTGYIPSNYVAPSDSIQAEEWYLGKITRREAERLLLSLENPRGTFLVRESETTKGAYCLSVSDYDASRGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKHADGLCHRLTAVCPTAKPQTQGLSKDAWEIPRDSLRLELKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGEMGRYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPDCPESLHDLMFQCWRKDPEERPTFEYLQAFLEDYFTATEPQYQPGDNL
What are the official names of this protein?
Tyrosine-protein kinase Src-2, p60-Src-2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
What are the subcellular locations of this protein?
Cell membrane.
Protein: SC61G_GADMO
Sequence: MDQIMQFVEPSRQFVKDSIRLVKRCTKPDRKEFQKIAMATAIGFAIMGFIGFFVKLIHIPINNIIVGG
What is the function of this protein?
Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across the endoplasmic reticulum (ER).  Forms a ribosome receptor and a gated pore in the ER membrane, both functions required for cotranslational translocation of nascent polypeptides (By similarity).  The SEC61 channel is also involved in ER membrane insertion of transmembrane proteins: it mediates membrane insertion of the first few transmembrane segments of proteins, while insertion of subsequent transmembrane regions of multi-pass membrane proteins is mediated by the multi-pass translocon (MPT) complex (By similarity).
What are the official names of this protein?
Protein transport protein Sec61 subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the SecE/SEC61-gamma family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: RL28_CAUSK
Sequence: MSRRCELTGIGPMVGHNVSHSNIKTKRRFLPALSPASLQSDSLGQTFKLRISNAALRTLDFRGGLDVFLLGAKDEQLSPRALKIKAQVKAKAKAAATAVAA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: COXX_BURPS
Sequence: MDTTLSHTPGSRLSQYLALTKPRVTQLAVFCAVIGMFLATPGMVPWKVLLGGTIGIGLLAGSAFAINCLVEQKIDAMMRRTAWRPSARGEITTLQILAFSTVLGGLGAWTLYTFTNPLTMWLTIATFVGYAVIYTLLLKPMTPQNIVIGGASGAMPPALGWAAVTGAVPGDAWILVLIIFVWTPPHFWVLALYRRKDYENAGLPMLPVTHGEQFTRLHILLYTVILFAVTMMPFISGMSGAVYLTSAVLLGALFLAYAWKIYRDYSDALARRAFRYSIVYLSLLFAALLVDHYARPVIGM
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GRDA_CARHZ
Sequence: MAILAGKKVIAVGDRDGVPGPAIAECAKSAGAEVVFATTECFVUTAAGTMDLQNQARIKELAEELGGENIVVLLGAAEPDTASLAAETVTLGDPTFAGPLAGVSLGLKVYHILEPEIKAEIDPAVYEEQAAMMEMVLDVDALAAEVSKMRKEGSKY
What is the function of this protein?
In the first step of glycine, betaine and sarcosine reductases, the substrate is bound to component PB via a Schiff base intermediate.  Then the PB-activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a carboxymethylated selenoether and the respective amine.  By action of component PC, acetyl phosphate is formed, leaving component PA in its oxidized state.  Finally component PA becomes reduced by the thioredoxin system to start a new catalytic cycle of reductive deamination (By similarity).
What are the official names of this protein?
Glycine/sarcosine/betaine reductase complex component A, Selenoprotein PA, Thioredoxin reductase complex selenoprotein A.
What is the protein family that this protein belongs to?
Belongs to the GrdA family.