PharMolix/UniProtQA huggingface dataset:
Protein: CZS15_CRUCA
Sequence: GFLDIVKGVGLVALGAVSKS
What is the function of this protein?
Has antimicrobial activity.
What are the official names of this protein?
Cruzioseptin-15, CZS-15.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Cruzioseptin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL10_BLOFL
Sequence: MVLSIKKKEQIVCKIQEVFKISSSAVIASLSNITSNSMNQLRKESRDCGVYIKVIPNTLLRRALKNSLYECLSNFCIGQNIIAFSINNPSDAARVLVNFSKNNEYFKIAGAVCEGNFIDKDQIDMLSRLPNYNESLLQLILILKVMSVGKLINVLKILSNQIIEE
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: NAGA_RAT
Sequence: MRSGQSAALAPVLQFTNCRILRGGTLLREDLWVRGGRILDPEKLFFEERRVADEQRDCGGRILAPGFIDVQINGGFGVDFSRATEDVGSGVALVARRLLSHGVTSFCPTLVTSPPEVYHKVLPQIPVKSGGPHGAGVLGVHLEGPFISREKRGAHPEAYLRSFGANAFHDVLATYGPLDNVCIVTLAPELDRSHEVIQALTAKGIRVSLGHSVADLRAAEVAVQSGATFITHLFNAMLPFHHRDPGIVGLLTSDQLPPGHCIFYGMIADGIHTNPAALRIAHRAHPQGLVLVTDAVPALGLGNGRHTLGQQEVEVDGLIAYIAGTKTLSGSIAPMDVCIRHFLQATGCSVESALEAASLHPAQLLGLEKTKGSLDFGADADFVVLDDTLHVQATYISGELVWQAEEAGL
What is the function of this protein?
Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6-phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway.
What are the official names of this protein?
N-acetylglucosamine-6-phosphate deacetylase, GlcNAc 6-P deacetylase, Amidohydrolase domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. NagA family.
Protein: KGUA_THIDA
Sequence: MTPPASPGVLYIVSAPSGAGKTSLVKALLKSDPAIRLSVSHTTRAPRPGESDGRDYHFVARDTFEKMLADGEFLEHAEVYGNFYGTSRGRIGQELDAGRDLLLEIDWQGAEQVKRHFPQSTSIFILPPTFSALRTRLTGRGQDSPEIIERRLAAAAHDVAHAEAFDYIIVNDDFDHALQDLVAITRSIRLEAQRQLKRHAALFGEFRRI
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HR1_ARATH
Sequence: MPLVELLTSAALGLSLQLLHDAIIRAKERSLITRCILDRLDATLHKITPFVIKIDTLTEEVDEPFRKVIEELKRLLEKAIRLVDAYAELKLRNLLRKYRYKRRIKELDSSLRWMIDVDVQVNQWLDIKKLMGKMSEMNTKLDDITRQPMDIIEATGRSSEEDGCTKPTIDIHFRWKNQTKEHEIRFIFK
What is the function of this protein?
Probable disease resistance (R) protein.
What are the official names of this protein?
RPW8-like protein 1, AtHR1.
What is the protein family that this protein belongs to?
Belongs to the plant RPW8 protein family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SAMP_BOVIN
Sequence: MNKLMSWVSVLIILPEAFAQTDLRGKVFVFPRESSTDHVTLITKLEKPLKNLTLCLRAYSDLSRGYSLFSYNIHSKDNELLVFKNGIGEYSLYIGKTKVTVRATEKFPSPVHICTSWESSTGIAEFWINGKPLVKRGLKQGYAVGAHPKIVLGQEQDSYGGGFDKNQSFMGEIGDLYMWDSVLSPEEILLVYQGSSSISPTILDWQALKYEIKGYVIVKPMVWG
What are the official names of this protein?
Serum amyloid P-component, SAP.
What is the protein family that this protein belongs to?
Belongs to the pentraxin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PGPSD_DROSI
Sequence: MTWIGLLIVGLTAIAVQGEVPIVTRAEWNAKPPNGAIDSMETPLPRAVIAHTAGGACADDVTCSQHMRNLQNFQMSKQKFSDIGYHYLIGGNGKVYEGRSPSQRGAFAGPNNDGSLGIAFIGNFEKQAPNKEALDAAKELLEQAVKQAQLVEGYKLLGHRQVSATMSPGEALYALIQQWPNWSEEM
What is the function of this protein?
Peptidoglycan-recognition protein that plays a key role in innate immunity by binding to peptidoglycans (PGN) of Gram-positive bacteria and activating the Toll pathway.  Has no activity against on Gram-negative bacteria and fungi.  Shows some partial redundancy with PRPGP-SA in Gram-positive bacteria recognition.  May act by activating the proteolytic cleavage of Spatzle and the subsequent activation of Toll pathway.  Recognizes S. aureus PGN (By similarity).
What are the official names of this protein?
Peptidoglycan-recognition protein SD.
What is the protein family that this protein belongs to?
Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: XLRS1_MOUSE
Sequence: MPHKIEGFFLLLLFGYEATLGLSSTEDEGEDPWYQKACKCDCQVGANALWSAGATSLDCIPECPYHKPLGFESGEVTPDQITCSNPEQYVGWYSSWTANKARLNSQGFGCAWLSKYQDSSQWLQIDLKEIKVISGILTQGRCDIDEWVTKYSVQYRTDERLNWIYYKDQTGNNRVFYGNSDRSSTVQNLLRPPIISRFIRLIPLGWHVRIAIRMELLECASKCA
What is the function of this protein?
Binds negatively charged membrane lipids, such as phosphatidylserine and phosphoinositides (PubMed:17325137, PubMed:20677810).  May play a role in cell-cell adhesion processes in the retina, via homomeric interaction between octamers present on the surface of two neighboring cells (By similarity).  Required for normal structure and function of the retina (PubMed:11983912, PubMed:17325137).
What are the official names of this protein?
Retinoschisin, X-linked juvenile retinoschisis protein homolog.
What are the subcellular locations of this protein?
Secreted. Cell membrane; Peripheral membrane protein; Extracellular side. Note=Binds to phosphatidylserine-containing lipid membranes and embeds itself partially into the lipid bilayer. Lipid-binding requires the presence of Ca(2+) ions.
Protein: WHIA_BACC0
Sequence: MSFASETKKELTNLEMKECCEKAELSALLRMNGSLSFSNRRLSIDIQTENAAIARRIYTLLKKGYDVTVELLVRKKMRLKKNNVYIVRLVEKSREILADLHIVRDDFSFIRNISQELIEKKCCKRSYLRGAFLAGGSVNNPETSSYHLEIFSLYKEHNDAICELMNGFDLNSKTLERRKGYITYLKEAEKITEFLNIIGAHNALLRFEDIRIVRDMRNSVNRLVNCETANLNKTIGAALRQIENIRYIDETVGLDILPDKLREIAQLRRDYQDVTLKELGEMVSGGKISKSGINHRLRKIDDIAEKLRAGETVAKK
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: RS20_CLOBH
Sequence: MANIKSAKKRIKVIETKTLRNKMLKSSLKTTIKNFLTVVEGKNVEEAKAAYKTAARALDMSVSKGIVHKNKAARTKSRLAAKLNALNA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: UBIE_CUPPJ
Sequence: MSETHFGFEKVDETEKAGKVAGVFHSVASKYDVMNDLMSGGMHRLWKMFTIAQANVRPGHKVLDIAGGTGDLAKAFAKQAGPTGQVWLTDINESMLRVGRDRLLDKGVVTPVALCDAEHIPFPDNYFDLVTVAFGLRNMTHKDAALAEMRRVVKPGGKVMVLEFSKVWKPLEKAYDVYSFQVLPWLGQKVAGDAASYRYLAESIRMHPDQTSLVRLMEQVGLEKVEYFNLTAGVVALHVGRKY
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: DPOL_NPVCF
Sequence: MKIVTYNQLQEAFRDYSPRDFAISRDNVFRVMRIYYNENVGQLVAFCNTQLAGRLAQFYFTIKMDLYSYKQCYNSHIFATCRNRCSSYNTFVAPGVKNVYMDKINVIKFKRNGSSFGEKAAALDKFLHNANRVHMQTPVIEGTYMRFRRAQRCRNNCVTDDARPFELERFADDFQVVNPATLTTKIEPVMACFDIETHSDGHNSSKPECDVIMCIGLAVLKDNRYDKICFVYHKELVEISGNDEYTHVVVFNNESHMIASFFDFFKYANPDVILDYNGDVFDLPYIRGRLKGDKPLLGRYDLPALQPNTKLFITKIGNRTDTYYFNYYIHIDLYKYFGADANKRDVENFELNTLSQYYLNDNKVDLNWQTMVAMYNNKQLGTMIDYNLKDCLLPIRLFNKLKLNDFMYSQCLMYRLCTDDFICNISHLISSTFFHLALTNTRTDPVTGLVVHDPYFFNKDDLGRMSSKDAGFCAGMSRLQRKRIPLKDLPANSIRLGAINEIVNYEGGKVLQPRAGVYEFAFSLDFNSLYLTIMIDICACLTNLILCEDGNVYLNQDKQAINVQLLLQLLKQRSELKKCRDSQTDSEFLYDLYDQMQNLSKRTANSIYGYYGIFCKLLANYITRVGREKLTAAIGMIEGLSNDAELLSKFNLSTLTFRVLYGDTDSTFVLPTFKRDEIPEESCMVTLTRICAAVETRVNGLFANGYKMAFENLMSVLILLKKKKYCYINSANKIVFKGWLVKKDMPVFMRVAFRTAIEQVLRHQDLQKCLDSLLINMLMYFDAFGTTKPLTDYSFSMTYNDGAGKVTENESRPTKRRVVTVARHCREILLNKGTDFVPGNGDRIPYVLLDIQGSVTQKAYPLRLFDPRTMRISWLKHMTILNTFMNELLEIFGDEHTSALNKCYDAILTKYMQHQAYDKKRVTLIKINAAYKRKAPSDDAARKRARAGPSALRKQKAASNDEDSSDEDDEDCSQAIGSNNTFKFSLYKYK
What is the function of this protein?
Replicates the viral genome, host DNA polymerases cannot substitute for the viral enzyme in this process.
What are the official names of this protein?
DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
Protein: GLMU_CAMC5
Sequence: MNDTSIIILAAGLGTRMKSKRPKVLFELCGEPMIIHILKQAYAITNDVGVVLHYEKELISQKIKEIFPQTKIYTQDLENFPGTAGALKNATLSGKKVIVTCGDMPLVRSTDLMRLANADADIAMSCFEAANPFGYGRVIIKGGKVGAIVEQKDASEAELAIKSVNAGCYCFKREILEEILPLIKNKNTQKEFYLTDTIKIANERGFKCVAVNVSEQNFMGINDKFQLSVAEKIMQDEIKQDLMKAGVLMRLPESIFIDSRAKFEGECVLEENVSIMGACHIKESIIKSCSVIEDSVIEGSDIGPLAHIRPKSEIKNTHIGNFVEVKKGVLDGVKAGHLSYLGDCEIASGTNVGCGTITCNYDGKAKYKTTIGKNVFIGSDTQLVAPVNIADDVIIAAGSTITNDVPSGALAISRGKQENKAGFFYKFFGKNNAEK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_CHLTB
Sequence: MSFKSIFLTGGVVSSLGKGLTAASLALLLERQDLKVAMLKLDPYLNVDPGTMNPYEHGEVYVTDDGVETDLDLGHYHRFSSVQLSKYSIATSGQIYTKVLTKERNGEFLGSTVQVIPHVTNEIINVIQSCADHHKPDILIVEIGGTIGDIESLPFLEAVRQFRCEHPQDCLSIHMTYVPYLRAAKEIKTKPTQHSVQNLRSIGISPDVILCRSEAPLSTEVKRKISLFCNVPEHAVFNAIDLERSIYEMPLLLAKENISDFLLNKLGFSPKPLDLSDWQDLVEALCDKERQHVRIGLVGKYLEHKDAYKSVFEALFHASVPANCSLELVPIAPESEDLLEQLSQCDGCLIPGGFGTRSWEGKISAARYCREQNIPCFGICLGMQALVVEYARNVLDKPLANSMEMNPETPDPVVCMMEGQDSVVKGGTMRLGAYPCRIAPGSLASAAYKTDLVQERHRHRYEVNPSYIERLEEHGLKIAGVCPLGELCEIVEIPNHRWMLGVQFHPEFLSKLAKPHPLFIEFIRAAKAYSLEKANHEHR
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: SYI_HALWD
Sequence: MDEVDDQYTPADVETAIETYWDDTNAYEATKEAHADDPSFFFVDGPPYTSGQMHLGTAWNKTLKDAIIRYKRMTGHHVTDRPGYDMHGLPIEVKVEEELGFETKRDIEEYGMESFIEECKRFAVDNRKAMDEDFQSIGVWMDWDNPYETLSPEYMEAAWWAFQQVDDRGLVERGKRSVSYCPRCQTAIAANEVEYDEITSPSIYVRFPLSNKEGSLVIWTTTPWTIPANTFVAVDKDLTYQAVRAEQGDDSEVLYIAESCVEDVLKQGRYDDYTVVEEYSGDELTGWEYDHPLADQVQTYADFAGAGEVYTAEYVEADRTGLVHSAPGHGQEDFARGQELDLETFVPVDGRGEFTEAAGQYTGTFVRDANDEIINDLDEEGVLLSSGTHEHRYGHCWRCDTDIIFLATDQWFITVTDIKDELLDNINDSEWYPQWARDNRFRDFVADAPDWNVSRQRYWGIPLPIWESVDDADTGDNSTSDDWIVIGTREELAERADQDVNPAEIDLHRPAVDPLTITENGSRYERVPDVFDVWIDSSVASWGTIDYPGETDAYDELWPADFIVEAHDQTRGWFWSQLGMGTAATGQVPYEEVMMHGFANDENGRKMSKSRGNIVTPEEAIDRAGRDPLRAYLLSHDQQGVDLSFEWDGLGEMQSTLNIFWNVFRFPLPYMDLDGYDPATADLSEGSMNIVDEWVLSRLQSVKATTRAAWEEYEIDTAVNTILEFITDDVSRFYIKAIRERMWADEDSASKRGAYATLSTVLDETIRLLAPIAPYLTEQMYQHLNGSETTVHALSYPSVDPEWQNETLESEMAVLRDVEEAAANARQQGGRKLRWPVPRVIVEAEDDSIADAVESLSGLLADRVNTEAIETVTQFDELIERAQPEMSVIGPEFGADAQRVMDAIEGGSREILTEGVTIDGVQYEITDEMITFDAEPPAYISAADFDGGTVYVDTSLTESIEAEGYARDVIRRIQQMRKELALDVDTEIQTAVDVADDRVADLVAQQRDVVATETRTNAFVDNIDRASENGQALIEEWDVEGVTVTIGVAPLKAQLSDQS
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_DESVM
Sequence: MTTVSSDRIRIKLKAYDYRILDKAVAEIVDTARNTGAGVAGPIPLPTNIHKYTVNRSVHVDKKSREQFEMRIHKRLMDILEPTQQTVDALGKLSLPAGVDVEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: Y286_XANOR
Sequence: MPTSMPNDPCPCGRPADYARCCGPYHAGAAAPDAETLMRARYSAHVRRDAAYLLASWHPSTRPGELSLDEGGRTTWLGLTVQRTLETGPETAEVVFLARYRIGGGSAVRMTEHSRFVRDAGRWYYLDAR
What are the official names of this protein?
UPF0225 protein XOO0286.
What is the protein family that this protein belongs to?
Belongs to the UPF0225 family.
Protein: TAT_HV193
Sequence: MELVDPNLDPWNHPGSQPTTPCTRCYCKWCCFHCYWCFTTKGLGISYGRKKRRQRPRTPQSSQIHQDFVPKQPISQARGNPTGPKESKKEVESKAKTDP
What is the function of this protein?
Extracellular circulating Tat can be endocytosed by surrounding uninfected cells via the binding to several surface receptors such as CD26, CXCR4, heparan sulfate proteoglycans (HSPG) or LDLR.  Neurons are rarely infected, but they internalize Tat via their LDLR.  Through its interaction with nuclear HATs, Tat is potentially able to control the acetylation-dependent cellular gene expression.  Modulates the expression of many cellular genes involved in cell survival, proliferation or in coding for cytokines or cytokine receptors.  Tat plays a role in T-cell and neurons apoptosis.  Tat induced neurotoxicity and apoptosis probably contribute to neuroAIDS.  Circulating Tat also acts as a chemokine-like and/or growth factor-like molecule that binds to specific receptors on the surface of the cells, affecting many cellular pathways.  In the vascular system, Tat binds to ITGAV/ITGB3 and ITGA5/ITGB1 integrins dimers at the surface of endothelial cells and competes with bFGF for heparin-binding sites, leading to an excess of soluble bFGF.
What are the official names of this protein?
Protein Tat, Transactivating regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the lentiviruses Tat family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Secreted. Note=Probably localizes to both nuclear and nucleolar compartments. Nuclear localization is mediated through the interaction of the nuclear localization signal with importin KPNB1. Secretion occurs through a Golgi-independent pathway. Tat is released from infected cells to the extracellular space where it remains associated to the cell membrane, or is secreted into the cerebrospinal fluid and sera. Extracellular Tat can be endocytosed by surrounding uninfected cells via binding to several receptors depending on the cell type.
Protein: IKBB_MOUSE
Sequence: MAGVACLGKTADADEWCDSGLGSLGPDAAAPGGPGLGAELGPELSWAPLVFGYVTEDGDTALHLAVIHQHEPFLDFLLGFSAGTEYLDLQNDLGQTALHLAAILGEASTVEKLYAAGAGVLVAERGGHTALHLACRVRAHTCACVLLQPRPSHPRDASDTYLTQSQDCTPDTSHAPAAVDSQPNPENEEEPRDEDWRLQLEAENYDGHTPLHVAVIHKDAEMVRLLRDAGADLNKPEPTCGRTPLHLAVEAQAASVLELLLKAGADPTARMYGGRTPLGSALLRPNPILARLLRAHGAPEPEDEDDKLSPCSSSGSDSDSDNRDEGDEYDDIVVHSGRSQNRQPPSPASKPLPDDPNPA
What is the function of this protein?
Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm.  However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation.  Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.
What are the official names of this protein?
NF-kappa-B inhibitor beta, NF-kappa-BIB, I-kappa-B-beta, IkB-B, IkB-beta, IkappaBbeta.
What is the protein family that this protein belongs to?
Belongs to the NF-kappa-B inhibitor family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: KRF4_COLLI
Sequence: MSCYNPCLPCQPCGPTPLANSCNEPCVRQCQSSNVVIEPSSVVVILPGPILSSFPQNTVVGSSTSAAVGSILSCEGVPINSGCFDLSCITSRYCGSRCQPC
What are the official names of this protein?
Feather keratin Cos2-3, F-ker.
What is the protein family that this protein belongs to?
Belongs to the avian keratin family.
Protein: HSLR_AERSA
Sequence: MPNPAETTTQVRLDKWLWAARFYKTRSLARDQIEGGKVHYNGQRSKPGKAVEAGALIRVWQGQDEREVRVLQVSEQRKSAPLAQLLYEETEASLKKRAENSEARRFNSQFAPSPERRPDKQERRQLIKVKQY
What is the function of this protein?
May play an important role in binding of nucleic acid.  More specific for RNA (By similarity).
What are the official names of this protein?
Heat shock protein 15 homolog, HSP15.
What is the protein family that this protein belongs to?
Belongs to the HSP15 family.
Protein: THIC_BACC2
Sequence: MKQSVSAEQIELKSSLPGSKKVYVDGPREGMKVPMREIEQSETNGVPNPPIRVYDTSGPYTDPAYKVELEKGIPTPRHSWIMGRGDVDAYEGREVKPEDDGVKVASKHTPVFPQMDRKPLRAKQGANVTQMHYARNGIITSEMEYVAIREGVEPEFVRKEIAEGRAILPANINHPEAEPMIIGRNFHVKVNANIGNSAVSSSIAEEVEKMTWATRWGADTIMDLSTGKNIHTTREWIIRNAPVPVGTVPIYQALEKVNGIAEDLTWEVYRDTLIEQAEQGVDYFTIHAGVLLRYIPITAKRTTGIVSRGGSIMAQWCLFHHKENFLYTHFEEICEIMKQYDVSFSLGDGLRPGSIADANDEAQFSELETLGELTKIAWKHDVQVMIEGPGHVPMHLIKENMEKELDICQGAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVRTGVITYKIAAHAADLAKGHKTAHQRDDALSKARFEFRWRDQFNLSLDPERAMEYHDETLPAEGAKTAHFCSMCGPKFCSMRISHDIREYAKENDLETTEAIEKGMKEKAEEFKEAGSHLYQ
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: BIOB_HAEIG
Sequence: MLAEKLQINSITPHPSVEYWSVCKVEALFETPFLELVYRAAQIHRKHFNSRTIQLSTLMSIKTGGCPEDCGYCPQSARYHTGVQNQQLLDVNEIIAKAKIAKARGAGRFCMGAAWRGPKPKDIEKVTEIIKAVKSLGLETCGTFGLLQDGMAEDLKEAGLDYYNHNLDTAPEHYAEVIGTRRFDDRLSTLGKVRKAGLKVCCGGIVGMNETRKERAGLIASLANLDPQPESVPINQLVKVEGTPLADAEELDWTEFVRTIAVARITMPKSYVRLSAGRSGMTEEMQAMCFMAGANSIFYGDKLLVTDNPEEDGDQLLMAKLDLEPETAENKK
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: IOVO_LOPED
Sequence: LAAVSVDCSEYPKPACTMEYRPLCGSDNKTYGNKCNFCNAVVESNGTLTLSHFGKC
What are the official names of this protein?
Ovomucoid.
What are the subcellular locations of this protein?
Secreted.
Protein: TRPA_GEOSE
Sequence: MLLLSVNPPLFIPFIVAGDPSPEVTVDLALALEEAGADLLELGVPYSDPLADGPTIQRAAARALAGNMTLPKAIHLVAEMRKKGVTIPIILFTYYNPVLQLGEESFFALARENGANGVLIPDLPFEESGPLRELGERFDLPLISLVAPTSKQRIERIASVAQGFLYCVSSLGVTGMRETLPESLGDFVSEVKRHSRVPVAVGFGISTPEQVAMLKEVCDGVVIGSALVQKVEQLGERLLAPEEKEAAIAEFAAYARSLAAPLHAPCSLR
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: TYPH_BURP0
Sequence: MTFLPQEFIRKVRDRAPLDTADVARFVQGVTAGDVTEGQIAAFAMAVYFNELPLSARIALTLAQRDSGDVLDWRGARLNGPVVDKHSTGGVGDLTSLVIGPMVAACGGYVPMISGRGLGHTGGTLDKLEAIPGYDVAPSVDMLRRVVRDAGLAIVGQTAQLAPADKRIYAVRDVTATVESISLITASILSKKLAAGVSALAMDVKVGSGAFMPSAEQSAELARSIVDVGNGAGMRTAATLTDMNQALAPCAGNAIEVRCAIDFLTGAARPARLEAVSFALAAQMLTMGGLAADAHDARRRLRAVLESGAAAERFARMVAALGGPADLVERPERHLPRAAAAAPVAAARAGWIERIDARALGLAVVGLGGGRAKIGDTLDYSVGLSALAELGERVEAGQPLATVHARDADSAAQATDAVRRAYRIGAEPPAQTRVVHAVIE
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: SEPF_STAAT
Sequence: MSHLALKDLFSGFFVIDDEEEVEVPDKQQQVNEAPAKEQSQQTTKQNAIKSVPQKSASRYTTTSEERNNRMSNYSKNNSRNVVTMNNATPNNASQESSKMCLFEPRVFSDTQDIADELKNRRATLVNLQRIDKVSAKRIIDFLSGTVYAIGGDIQRVGTDIFLCTPDNVEVAGSITDHIENMEHSFD
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: GAL1_YERPS
Sequence: MSLKQHTQTIFRQQFDRESDITIKAPGRVNLIGEHTDYNDGFVLPCAINYETVISCGKRGDRQIRVIAADYENQQDIFSLDAPIVPHPEYRWADYVRGVVKHLQMRNADFGGADLVICGNVPQGAGLSSSASLEVAVGQALQSLYQLPLSGVELALNGQEAENQFVGCNCGIMDQLISALGKKDHALLIDCRTLETRAVPMPENMAVVIINSNIQRGLVDSEYNTRRQQCEAAARFFGVKALRDVEPSLFFSIQDELDPVVAKRARHVISENARTLAAADALAAGNLKLMGQLMQESHISMRDDFEITVPPIDRLVEIVKSVIGDQGGVRMTGGGFGGCIVALMPLELVEQVRTTVAQEYPAHSGGKKETFYVCQASQGAGLC
What is the function of this protein?
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.