PharMolix/UniProtQA huggingface dataset:
Protein: SMAP2_CHICK
Sequence: MTGKSVRDVERYQAVLGSLLSEEENKYCADCQAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTQEQIQCMQEMGNGKANRLYEAFLPENFRRPQTDQAVEGFIRDKYEKKKYMDRSIDINTFRKEKDDKWKKSNEPVSERKLEPIVFEKVKMPQKKEETQQSRKSSPKSTEPVIDLLGLDAPVPSTLTNGRPCSLEKDLDLFASVGLNSDSRKVSGSMPTSGSAGSVPENLNLFPEPGGKGEEAGKKQLSKDSILSLYGSQTPQLPAQGAMFMAPAQMAYPAAAYTSFPGVPPSSSMMGGMMAPSVGVMAQHGAAGMVTPMAIPAGYVGNVQAAVIGVPNGMMAAQQAGYVAGMAAVPQPVYGVQPAQQLQWNITQMTQQMAGMNFYGANGVMGYGQSMGGGGAQGSNQSLSTQLWK
What is the function of this protein?
GTPase activating protein.  May play a role in clathrin-dependent retrograde transport from early endosomes to the trans-Golgi network (By similarity).
What are the official names of this protein?
Stromal membrane-associated protein 2, Stromal membrane-associated protein 1-like.
Protein: LOLD_MARMM
Sequence: MSDFVLELDAIERTYVTEAGELPVLRGASLSLAPGEIVGLVGPSGSGKSSLLHAAGLLERPDAGEVRVRGQATRDLDDRARTAIRRRDIGFVYQFHHLLPEFDALENIVLPQLIAGVPSARARQRAEELLTRLGLAERLLHQPSQLSGGEQQRVAIARALANAPHVLLADEPTGNLDPDTSDTVFAAFRDTVRAEGAAALVATHNHELAGRMDRILTFADGHLTPYVPA
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ATPE_BRUC2
Sequence: MAQAFQFELVSPERLLLSAQVTEVVIPGSEGYLTALAGHSPLMTTIMPGVVSVKLADGKTDSYVVFGGFADITPQGCTVLAESATHVDDIDPADIQHRIDHARKVLEDASSNEHRTKAEIFLHQLMTLQGAILPA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HIS1_RHOPT
Sequence: MSAPFVLAVPSKGRLQENAEAFFARAGLTLSKPGGARDYRGTIAGLDNVEVAYLSASEIAANLARGSVHFGVTGEDLVRESITDADKRVLLIDGLGFGYANVVVAVPQAWIDVRTMADLDDVTTGFRAQHNRRMRVATKYINLTRGFFAQHNVVDYRIVESAGATEGAPAVGTAEMIVDITTTGATLAANGLKVLDDGVMLRSQANLVASREADWSDTARETARVILDHIASRARAGKYKEVRTRFKGCNDALLAEAHSRFGVVSPFGGPTSSGMLTLHCPPAQIYALGSFLRQHGADTVSVAALDYVFDKENPLFSKLAAFLPQ
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_XYLFA
Sequence: MADQKIQIRLKAFDCRLIDRSAGEIVETAKRTGAHVRGPIPLPTKIERCTILVSPHADKDARDQYETCTYKRVLYIVDPNDKTVDALMKLELAAGVDVQIKLT
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RL13_MACCJ
Sequence: MRQTFMANESNIDRKWYVIDAEGKTMGRLSSEVASILRGKHKPTFTPHVDCGDHVILINAEKIYLSGNKAEDKIYYRHSNHPGGIKSISAGELREKNPVRLMETSIKGMLPKGSLGDKMFKKLHVYAGAEHPHTAQQPENYELRG
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: Y170_BORBR
Sequence: MHNIPPEESLIEYPSDFPIKVMGKQHPEFAQTLTEVVLQFDPAFDPASVEMRPSKGGNYMGLTFTVRATSREQLDSLYRALHGHPMVSIVL
What are the official names of this protein?
UPF0250 protein BB0170.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.
Protein: PYRD_ANADF
Sequence: MIWPALRWTLFHLDPERAHRLAHGALHRVPPGLARLRRPAVPPELRVSCLGLDFDGPIGLAAGFDKGDASIAGLFALGFSHVEIGTITPRPQAGNEPPRLFRLVEHRALVNRMGFNNAGAEVCARRLAGVPATARMGPVGVNVGKNKTTPNEDAAADYLACIDRLHPYADYLVVNISSPNTPGLRQLQERDQLDALLRACAGRLRERAPGKPLLVKLAPDLSPTALDEAVDVAIDAGVSGIVATNTTLSRAGVERHPRAREAGGLSGAPLEALATSVVRRCYIRAAGRVPIVGCGGVMNAEGAYAKIRAGATLVQVYTGLVYGGPGFVRRLNDGLARLLARDGFRTVAEAVGADVETAERAGV
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: UBP36_DROGR
Sequence: MPVSLAVCETTANVVNAALRESLGSCVARAALSADEAKTSNGGGDGSSTSGSSTDNLQSQIVANAKRVLLAKIDYEEVDNYHESVLAKLKSKYIVIKPDSNGGAASNGNGNYNGSNKTNGKFGAGNGHDNNGNGNGIVNGGTSALNGGNNRKQIVVVDHQSSNQHGSPSNPNELPKPKRVLYQREHIRIGWKQSERKWQVGTGMLNVGNTCYLNSSLQALFHIPSLANWLVSESAHLENCNISESCGSNGCIICAMAKTLQSTQSNQSAVRPFLIYSKLRQICKHMVVGRQEDAHEFLRFLIEAMEKAYLMRFRNYKELDQLVKETTPLNQIFGGYLRSEVRCLSCNHVSITFQHFQDLLLDIRKSDTLEDAFDGYFSRERLEDMGYKCEGCKKKVSATKQFSLERAPITLCIQLKRFSMMGNKLTKQISFKPRIDLSRFAARSPTAAAQPLSYRLVSMVTHLGVSQHCGHYTAIGLTETGSYYNFDDSCVRPIAMQSVCNTNAYIMFYELDVNGNGHVVAPKMNGMRLTTNGGQQHSSPVVATAPAAVVSATATSTSASVSAAAVTSPRFIGPQLPNGYGNSNGHALGGGAAKTAIQFKTTPQKHQQQQQAQTQYQLNGHINGAAKFQTGAANANANKSSCNTLNNSKQHQPQQQQQQPQHILPISSDEEEDSDDDNDNDNVKTNKAPQLPSMPKMFEESSESVALTAKLKPKTALKSLVPYESASEEEEQQQQQQQQTLQQQAATNSRKRRSGADSSDTDDDDDEEQQQQQQQQPSLILRNGHAKTNGNLLNSSSSKTKSASNASSANVNSSKQKTDAIDEIFKSLNNYKNKHRNDHNHVDDDDDDDEDEDEDEDEAQAQAEKKTVTKSSSSSSSTSLTNGWQQSQNGKATASPKTPPSPAVIKTKTGIWQVTRNDEDDDENVDGVADADDDDDNDEVAEPAVVTAKNHKNPFAAGKATATTDANPSAKRQKLLNGSSKSQQTTPRIGNGYQGESLPNGNAVVSELLKQNHRGYGSSVLSWNGKASELDKETFDLVCAKRIAGYGAAAADEHCCDVNSGHSSNYGTNYKSLNNDMSSSSSSSSSTNSSSNSSSRSNGNSSNCPPCDLLAEAREQRKRDDDDEEENEMDRGRQRKIKSASVKCGSGATAAPPGYNPFQEYESQKRWHSNKSGSYSRFYHHPNYRSNFQQRNKFKHNRFAGGGGGAKFQQQRALQRHLASGGGFTRRQHHQSSGQQQQQS
What is the function of this protein?
Required for maintaining multiple types of adult stem cells, including male and female germline, epithelial follicle cell and intestinal stem cells.  May function as a transcriptional repressor by continually deubiquiting histone H2B at the promoters of genes critical for cellular differentiation, thereby preventing histone H3 'Lys-4' trimethylation (H3K4).  Controls selective autophagy activation by ubiquitinated proteins.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 36, Deubiquitinating enzyme 36, Protein scrawny, Ubiquitin thioesterase 36, Ubiquitin-specific-processing protease 36.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RNH2_METB6
Sequence: MICGVDEAGKGSVLGPMVIAGVGVGSTEMIDGFGLRDSKQLSPSERERLFVLIKKKCKVATVVISAAEIDAFRREMTLNTCVARAHAVVIAQLAPEIAYVDACDVNPFRYAETVRGYLSSPCEIVSEHHADSTYPVVSAASIVAKVTRDREIAKLAKKYGQIGSGYPSDPETIAYLNAYIDEHRIPPPIARKSWKTVSTLLAKKTQSSLTSFF
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_BRUSI
Sequence: MSISASLVKELRDLTGAGMMDCKAALAATEGKIEAAVDWLRAKGIAKADKKAGRTAAEGLVGVAASGNKAVVVEVNSETDFVARNDAFQELVRKIAQAALSTDGSSEAVANANVDGKTVTEAAKDAVATIGENISFRRSAALSVPQGVVATYIHNGVADGLGKLGVLVAIETAGDAEAAQAFGRQVAMHVAAVNPLALTSADVNPEAAEREKAIFIDQARQSGKPDNIIEKMVEGRMRKFYEEVVLLSQAFVINPDLTVEAALKDAEKAIGAPAKITGFARIALGEGIEKEESDFAAEVAAAAKG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LDHA_BOVIN
Sequence: MATLKDQLIQNLLKEEHVPQNKITIVGVGAVGMACAISILMKDLADEVALVDVMEDKLKGEMMDLQHGSLFLRTPKIVSGKDYNVTANSRLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNIVKYSPNCKLLVVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWILGEHGDSSVPVWSGVNVAGVSLKNLHPELGTDADKEQWKAVHKQVVDSAYEVIKLKGYTSWAIGLSVADLAESIMKNLRRVHPISTMIKGLYGIKEDVFLSVPCILGQNGISDVVKVTLTHEEEACLKKSADTLWGIQKELQF
What is the function of this protein?
Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+).
What are the official names of this protein?
L-lactate dehydrogenase A chain, LDH-A, LDH muscle subunit, LDH-M.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMY_THEON
Sequence: MRTFIIKANKAHTKADFKLKDLPGTSGRIDLLCRVLNSAFLLSHGFRKNVRVWLSLYGPPNPPKAIRFEGQGMKPKTLNPDELSTAKLIIKALKVGENLREPSKEIQVLPGIYVSNLTFEDIIRRTLKGATLYYLHEEGRPIERVNFSQNVAFVLGDHEGLTPEDEAFLSGIAEKVSIGRKSYLASHVVAYVNIFLDSITPPP
What is the function of this protein?
Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs.
What are the official names of this protein?
tRNA (pseudouridine(54)-N(1))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. TrmY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRAN_ECOLI
Sequence: MKRILPLILALVAGMAQADSNSDYRAGSDFAHQIKGQGSSSIQGFKPQESIPGYNANPDETKYYGGVTAGGDGGLKNDGTTEWATGETGKTITESFMNKPKDILSPDAPFIQTGRDVVNRADSIVGNTGQQCSAQEISRSEYTNYTCERDLQVEQYCTRTARMELQGSTTWETRTLEYEMSQLPAREVNGQYVVSITSPVTGEIVDAHYSWSRTYLQKSVPMTITVLGTPLSWNAKYSADASFTPVQKTLTAGVAFTSSHPVRVGNTKFKRHTAMKLRLVVRVKKASYTPYVVWSESCPFSKELGKLTKTECTEAGGNRTLVKDGQSYSMYQSCWAYRDTYVTQSADKGTCQTYTDNPACTLVSHQCAFYSEEGACLHEYATYSCESKTSGKVMVCGGDVFCLDGECDKAQSGKSNDFAEAVSQLAALAAAGKDVAALNGVDVRAFTGQAKFCKKAAAGYSNCCKDSGWGQDIGLAKCSSDEKALAKAKSNKLTVSVGEFCSKKVLGVCLEKKRSYCQFDSKLAQIVQQQGRNGQLRISFGSAKHPDCRGITVDELQKIQFNRLDFTNFYEDLMNNQKIPDSGVLTQKVKEQIADQLKQAGQ
What is the function of this protein?
Essential for F plasmid conjugative transfer.  May interact with the recipient cell surface to stabilize mating pairs initiated by F-pili.  May interact with TraG (Probable).  Transfer requires OmpA and lipopolysaccharide (LPS), which are possibly receptors for TraN (PubMed:9696748, PubMed:16272376).
What are the official names of this protein?
Mating pair stabilization protein TraN.
What are the subcellular locations of this protein?
Cell outer membrane. Note=Part of the protein is accessible to externally added proteases (PubMed:1593622, PubMed:16272376). A topology of the protein suggesting it is a beta-barrel has been proposed; this was not confirmed using bioinformatics programs available in April 2019 (Probable).
Protein: GLB7_ARTSX
Sequence: ALTALEKQSIQDIWTILKAVGLEFLQVKMFGKLFADHPEYKAHFDNFLTAIFSVAEDLVPKLRAHLHRVIDAFDLVIFALGRESLRGSLKDLGIFHTGRDIVDPVESLTGFKLMVAVIEEGLDTFRAVPEYSKGLEGRFGNVDNINENAPFR
What are the official names of this protein?
Extracellular globin-E7.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: NORC_HALHD
Sequence: MADGLTKSAARNIFYGGSLFFFLLFAALTAHSHWYMVNKSTDNEGLTESVVAGKHIWEKNMCINCHSIMGEGAYFAPELSNVWERYGGHQNPEAARAGLAAWIRAQPLGTQGRRQMPAYDFTDEEMSSLIDFLEWTDGIDDQDWPPHPAG
What is the function of this protein?
Component of the anaerobic respiratory chain that transforms nitrate to dinitrogen (denitrification).
What are the official names of this protein?
Nitric oxide reductase subunit C, NOR small subunit, Nitric oxide reductase cytochrome c subunit.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=May be attached to the membrane by a signal-anchor.
Protein: MRAY_AROAE
Sequence: MLLEFALWLGQDIRAFNVFGYITLRTVMAAMTALLISFACGPAVIRWLAAKKIGQAVRDDGPKSHLTKAGTPTMGGALIIIAIAVTTLLWGDLRNQYVWVTLLVTLGFGAVGWVDDWRKVVHRDPKGLASRWKYLWTSLIALAAALFLGLTANEPAQTELIVPFFKAVSYPLGMLGFVALSYFVINGTSHSVNLTDGLDGLAIMPTVMVAGALAIFAYVAGHAGFSKYLGVPYIAGAGELAVFCGALAGAGLGFLWFNAYPAEVFMGDVGALALGAALGTVAVVVRQEIVLFIMGGLFVAETLSVMVQVLYFKASGGKRIFRMAPLHHHYELGGWKETQVVVRFWIITIMLVLFGLSTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HVTJ_LACHE
Sequence: MKHLNETTNVRILSQFDMDTGYQAVVQKGNVGSKYVYGLQLRKGATTILRGYRGSKINNPILELSGQAGGHTQTWEFAGDRKDINGEERAGQWFIGVKPSKIEGSKIIWAKQIARVDLRNQMGPHYSNTDFPRLSYLNRAGSNPFAGNKMTHAEAAVSPDYTKFLIATVENNCIGHFTIYNLDTINEKLDEKGNSEDVNLETVKYEDSFIIDNLYGDDNNSIVNSIQGYDLDNDGNIYISSQKAPDFDGSYYAHHKQIVKIPYYARSKESEDQWRAVNLSEFGGLDIPGKHSEVESIQIIGENHCYLTVAYHSKNKAGENKTTLNEIYELSWN
What is the function of this protein?
This heat-sensitive bacteriocin inhibits the growth of closely related Lactobacillus species.
What are the official names of this protein?
Bacteriocin helveticin-J.
Protein: F16A1_CUPNH
Sequence: MTRISLTRYLVEEQRKHNTIQPELRLLIEVVARACKAISNAVSKGALAGVLGSAGTGNVQGETQQKLDVIANEVLLDANEWGGHLAAMASEEMESFYEIPNRYPKGEYLLMFDPLDGSSNIDVNVSIGTIFSVLHMPKPGQTVTEADFMQPGTHQVAAGYAVYGPQTTLVLTVGNGVHMFTLDREAGSFVLTHSNVTIPDDTKEFAINMSNMRHWAPPVRRYIDECLAGEEGPRGKNFNMRWVASMVADVHRILTRGGVFMYPWDKREPEKPGKLRLMYEANPMAMLVEQAGGAATNGHQRIMDVQPEKLHQRVSVILGSKNEVERVTRYHLEAEDKA
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1 1, FBPase class 1 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURC_GEOMG
Sequence: MYGKIEKIHFVGIGGIGMSGIAEVLLNLGYKVSGSDLKQSDTTDRLASLGGDIRFGHARENLADVDVVVTSTAVHDDNPEVMEAKRRMIPVIPRAEMLAELMRMKYGIAIAGTHGKTTTTSMVATALTHGGIDPTIVIGGKLNTLGTNAKLGQGQFLVAEADESDGSFLKLSPTIAVVTNIDADHLDFYTGGIEQIKDTFVDFINKIPFYGLAVLCLEDRNIAEILPRVKKRFVTYGLSSQADIRATHIRLEGGTTSFVAHYKGYRMGEVSFAMPGAHNVLNALACIAVAMELDVPFAQIQEGFAKFGGVGRRFQVKGEVNGITVVDDYGHHPAEIRATLAAGKSGWPDRRLVVAFQPHRFSRTKELFAEFVTCFYDADVLVLTDIYSAGEAPIEGVTAERLAENIRKHGQRDVTYIADREALPDHLLQIVRPGDIVLTLGAGNIWQTGEALLRKLETAEG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_RHOOB
Sequence: MARYTGPITRKSRRLRVDLVGGDQAFERRPYPPGQHGRARIKESEYLLQLQEKQKARFTYGVMEKQFRLYYKEANNRPGKTGENLLRILESRLDNVVYRAGLARTRRQARQLVTHGHLLVNNKKVDIPSYRVSQYDIIDVKEKSLSTLPFQVARETQGDRPIPGWLQVVGGRLRVLVHQLPERAQIDVPLQEQLIVEYYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: PTH_STRSY
Sequence: MTRLIIGLGNPGDRYFETKHNVGFMLLDKIAKRENVTFNHDKIFQADIATTFIDGEKIYLVKPTTFMNESGKAVHALMTYYGLDATDILVAYDDLDMAVGKIRFRQKGSAGGHNGIKSIVKHIGTQEFDRIKIGIGRPKGKMSVVNHVLSGFDIEDRIEIDLALDKLDKAVNVYLEEDDFDTVMRKFNG
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XYN2_RHIOR
Sequence: MVSFSSLFVAACAAVTAFALPNELEKRAITSNEQGTNNGYFYSFWTNGGGSVSYNNGAAGQYSVNWKDCGSFTSGKGWATGSARNINFSGSFNPSGNAYLAVYGWTTSPLVEYYIMENYGEYNPGSSMAHKGTVTSDGSVYDIYAHQQVNQPSIVGTATFNQYWSIRRNKRSSGTVTTANHFNAWSRLGMGLGSHNYQIVNTEGYQSSGSASITVS
What is the function of this protein?
Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.
What are the official names of this protein?
Endo-1,4-beta-xylanase 2, Xylanase 2, 1,4-beta-D-xylan xylanohydrolase 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 11 (cellulase G) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS11_BUCA5
Sequence: MVKNSTSIRTRKRVKKQILDGIAHIHASFNNTIVTITDRQGNALGWATSGGSGFRGSRKSTPFAAQVAAERCAEIVKDYGIKNLEVMVKGPGPGRESTIRALNAAGFRITNITDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: RPOB_SHESR
Sequence: MVYSYSEKKRIRKDFGKRPQVLDIPYLLSIQLDSFKKFTDQDPTGERGLEAAFRSVFPIKSFSGNSELQYVSYKLGEPVFDVKECQIRGVTYSAPLRVKLRMVLYDREAAAGTVKDIKEQEVYMGDIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDHDRGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDALFVRIDRRRKLPATIILRALEYSTQEILDLFFERVEFKIKKDTLVMTLVPERLRGETASYDIKDAEGSVLVEAGRRITARHIRQLEKTNTTELEVPVEYIVGKYAAQDYIDPDTGEVLVSANSEISLEDLAKLSLAGIKELSTLYINELDHGAYISDTLRIDPTTNRLEALVEIYRMMRPGEPPTKDAAEALFQNLFFSEERYDLSKVGRMKFNRRLSIPDDEGSGVLSKEDIVAVMKNIIHIRNGFDEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVRERLSLGDLNELMPQDLINAKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHPTHYGRLCPIETPEGPNIGLINSLASFARTNSYGFLETPYRKVVDGVITDDVEYLSAIEEGRYVIAQANIEVDSQGRMVEEQIACRHKGESTFMRASDIQYMDVSPQQIISVAASLIPFLEHDDANRALMGANMQRQAVPTLKSEKPLVGTGIERTLAVDSGVVVAAKRGGVIDYVDASRIVVKVNEDELRPGEAGIDIYNLTKYTRSNQNTCINQRPCCSVGEPVVRGDVLADGPSTDLGDLALGQNMRIAFMPWNGYNFEDSILISERVAQEDRFTTIHIQELSCIARDTKLGSEEITADIPNVGESALSKLDESGIVYIGAEVKGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNSVKGTIIDVQVFTRDGVEKDKRAIEIEEMHIAQARKDLGEEFKILEEGVLSRARNLLLSAGFTEAQIAALPRKDVLVQVIDDETKQTELEQLAEQHEELKADFDKKFEIKRRKITQGDDLAPGVLKIVKVYLAVKRTIQPGDKMAGRHGNKGVISKINPIEDMPYDEQGNPVDIVLNPLGVPSRMNIGQVLEVHLGAAAKGIGNKIAAMLEDQREKGLAEVRSYIKQVYELGDEVQQRVDIDSFTDDELLRLANNLKGGIPVATPAFDGAKEKEIKQMLELAGLPTSGQLKLFDGRTGNEFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTQMYKNIVDGNHQMQPGMPESFNVLLKEIRSLGINIELDQE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: IRS4_HUMAN
Sequence: MASCSFTRDQATRRLRGAAAAAAAALAAVVTTPLLSSGTPTALIGTGSSCPGAMWLSTATGSRSDSESEEEDLPVGEEVCKRGYLRKQKHGHRRYFVLKLETADAPARLEYYENARKFRHSVRAAAAAAAAAASGAAIPPLIPPRRVITLYQCFSVSQRADARYRHLIALFTQDEYFAMVAENESEQESWYLLLSRLILESKRRRCGTLGAQPDGEPAALAAAAAAEPPFYKDVWQVIVKPRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRCGHSEQYFFLEVGRSTVIGPGELWMQVDDCVVAQNMHELFLEKMRALCADEYRARCRSYSISIGAHLLTLLSARRHLGLVPLEPGGWLRRSRFEQFCHLRAIGDGEDEMLFTRRFVTPSEPVAHSRRGRLHLPRGRRSRRAVSVPASFFRRLAPSPARPRHPAEAPNNGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSGGRFRLYFCVDRGATKECKEAKEVKDAEIPEGAARGPHRARAFDEDEDDPYVPMRPGVATPLVSSSDYMPMAPQNVSASKKRHSRSPFEDSRGYMMMFPRVSPPPAPSPPKAPDTNKEDDSKDNDSESDYMFMAPGAGAIPKNPRNPQGGSSSKSWSSYFSLPNPFRSSPLGQNDNSEYVPMLPGKFLGRGLDKEVSYNWDPKDAASKPSGEGSFSKPGDGGSPSKPSDHEPPKNKAKRPNRLSFITKGYKIKPKPQKPTHEQREADSSSDYVNMDFTKRESNTPAPSTQGLPDSWGIIAEPRQSAFSNYVNVEFGVPFPNPANDLSDLLRAIPRANPLSLDSARWPLPPLPLSATGSNAIEEEGDYIEVIFNSAMTPAMALADSAIRYDAETGRIYVVDPFSECCMDISLSPSRCSEPPPVARLLQEEEQERRRPQSRSQSFFAAARAAVSAFPTDSLERDLSPSSAPAVASAAEPTLALSQVVAAASALAAAPGIGAAAAAAGFDSASARWFQPVANAADAEAVRGAQDVAGGSNPGAHNPSANLARGDNQAGGAAAAAAAPEPPPRSRRVPRPPEREDSDNDDDTHVRMDFARRDNQFDSPKRGR
What is the function of this protein?
Acts as an interface between multiple growth factor receptors possessing tyrosine kinase activity, such as insulin receptor, IGF1R and FGFR1, and a complex network of intracellular signaling molecules containing SH2 domains.  Involved in the IGF1R mitogenic signaling pathway.  Promotes the AKT1 signaling pathway and BAD phosphorylation during insulin stimulation without activation of RPS6KB1 or the inhibition of apoptosis.  Interaction with GRB2 enhances insulin-stimulated mitogen-activated protein kinase activity.  May be involved in nonreceptor tyrosine kinase signaling in myoblasts.  Plays a pivotal role in the proliferation/differentiation of hepatoblastoma cell through EPHB2 activation upon IGF1 stimulation.  May play a role in the signal transduction in response to insulin and to a lesser extent in response to IL4 and GH on mitogenesis.  Plays a role in growth, reproduction and glucose homeostasis.  May act as negative regulators of the IGF1 signaling pathway by suppressing the function of IRS1 and IRS2.
What are the official names of this protein?
Insulin receptor substrate 4, IRS-4, 160 kDa phosphotyrosine protein, py160, Phosphoprotein of 160 kDa, pp160.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: UPP_BRUO2
Sequence: MGVTVVSHPLVQHKLTIMRKKETSTASFRRLLKEISLLLCYEVTRNLELTTMSIETPLMPMEAPVLEGKKLVFASILRAGNGLLEGMLDLVPAARVAHIGLYRDHDTLQPIEYYFKAPEDIVNRLVIVVDPMLATANSAIAAIDKLKERGATNIRFLCLLAAPEGIERFTKAHPDVEVFTASIDERLDEKGYIVPGLGDAGDRMYGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: XERD_XYLFA
Sequence: MTPRTTNQRRQLARQQPPLLPEDATTIAHFLDALWIKHGLSQHTLNSYRRDLEGLARWNNGRAGPLATLTPPALLDYLTWRTQQHYSPLSNARLLSVLRTFFSYAVECGWRNDNPSTLLAHPVLPHPLPKALTESQIEALLAAPSIETPEGLRNRAMLELMYAAGLRVSELVTLPVAMLNRRQGVLRIIGKGGKERLVPLGEESQHWLQRYLEQARPSLAADKPIPADSDGDVPLFINTTLKRLSRQQFWRWIKHYAALAGIAPNKVSPHVLRHSFATHLLNHGADLRALQMLLGHRSISTTQIYTFIARQHLQQLHAQHHPRA
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids (By similarity).
What are the official names of this protein?
Tyrosine recombinase XerD.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.