PharMolix/UniProtQA huggingface dataset:
Protein: DEOC_MACCJ
Sequence: MNLAKYIDHTALKPETTKAQIAQLAQEAREYEFMSVCVNPAHVKYAKSLLEGTDVLVCTVIGFPLGANTPAVKAFETKDAIADGAGEVDMVINIGALKDKNYDLVAEDIKAVVDAAGDVTTKVIIETALLTDEEKVKACEIAQAQGADFVKTSTGFSTGGATKEDVALMRKTVGPDMGVKASGGVRSYEDVMTMIEAGATRIGASAGVQILKGEEAKGDY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MKKS_HUMAN
Sequence: MSRLEAKKPSLCKSEPLTTERVRTTLSVLKRIVTSCYGPSGRLKQLHNGFGGYVCTTSQSSALLSHLLVTHPILKILTASIQNHVSSFSDCGLFTAILCCNLIENVQRLGLTPTTVIRLNKHLLSLCISYLKSETCGCRIPVDFSSTQILLCLVRSILTSKPACMLTRKETEHVSALILRAFLLTIPENAEGHIILGKSLIVPLKGQRVIDSTVLPGILIEMSEVQLMRLLPIKKSTALKVALFCTTLSGDTSDTGEGTVVVSYGVSLENAVLDQLLNLGRQLISDHVDLVLCQKVIHPSLKQFLNMHRIIAIDRIGVTLMEPLTKMTGTQPIGSLGSICPNSYGSVKDVCTAKFGSKHFFHLIPNEATICSLLLCNRNDTAWDELKLTCQTALHVLQLTLKEPWALLGGGCTETHLAAYIRHKTHNDPESILKDDECTQTELQLIAEAFCSALESVVGSLEHDGGEILTDMKYGHLWSVQADSPCVANWPDLLSQCGCGLYNSQEELNWSFLRSTRRPFVPQSCLPHEAVGSASNLTLDCLTAKLSGLQVAVETANLILDLSYVIEDKN
What is the function of this protein?
Probable molecular chaperone that assists the folding of proteins upon ATP hydrolysis (PubMed:20080638).  Plays a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia (PubMed:20080638).  May play a role in protein processing in limb, cardiac and reproductive system development.  May play a role in cytokinesis (PubMed:28753627).
What are the official names of this protein?
Molecular chaperone MKKS, Bardet-Biedl syndrome 6 protein, McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytosol. Nucleus. Note=The majority of the protein resides within the pericentriolar material (PCM), a proteinaceous tube surrounding centrioles. During interphase, the protein is confined to the lateral surfaces of the PCM but during mitosis it relocalizes throughout the PCM and is found at the intercellular bridge. The MKSS protein is highly mobile and rapidly shuttles between the cytosol and centrosome.
Protein: PSTB_BACCZ
Sequence: MVATVVNVQVKNEEKIETAPKKVVFDTKNLNLWYGEDHALKDINLSIHENEVTAIIGPSGCGKSTYLKTLNRMVELVPIVRTTGVIEYRERNIFDKSYPVEELRTHVGMVFQKPNPFPKSIYENVAYGPKIHGISDKKTLDEIVEKSLRGAAIWDELKDRLHDNAYGLSGGQQQRLCIARCLAIEPDVILMDEPTSALDPISTLKVEELIQELKKDFSIVIVTHNMQQAARISDKTAFFLSGEVVEYTDTNKLFTTPSDKRTEDYITGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MSCL_PSYWF
Sequence: MSMMSEFKEFALKGNVMDLAVGVIIGGAFSGITNSLVEDIIMPIVAFIAGGELNFKNMFILLGDAPEGVAMTYDALKEAGVPLLAYGSFITVLINFLILAFIIFMMVKGMNKMRRKNEVEEVVEETPSEEVLLLREISQKLSK
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: URE23_PSEU2
Sequence: MLLTPTELERLTLYTAAELSRKRRSKGLRLNFPEASALIADEILEGAREGRSVAELIGFGSTILNTDDVMPGVADLLPVLQVEGTFPDGTKLVTVHQPIRPGQLPLAVMPTPGEILAPDGDIHLNGDRPTATLRAINTGDRPVQIGSHYHFFEVNKALDFPRERAFGMHLDIPAGTAVRFEPGELREVQLVQFGGTGDIHGFSGLTNGNLHDPACKLAALERARAQFFKGA
What are the official names of this protein?
Urease subunit gamma/beta, Urea amidohydrolase subunit gamma/beta.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGC_RHOOB
Sequence: MRSQPHVLGIVLAGGEGKRLYPLTADRAKPAVPFGGAYRLIDFVLSNLVNAGYLRLCVLTQYKSHSLDRHISQTWRLSGFAGEYITPVPAQQRLGPRWYTGSADAILQSLNLVYDEDPEYIVVFGADHVYRMDPEQMVQHHIESGAGVTVAGIRVPRSEAFAFGCIDSDESGRIVQFLEKPAHPPGTPDDPNMTFASMGNYVFTTKVLVDAIRADSENSDSDHDMGGDIIPALVEAGEASVYDFKDNVVPGATDRDRGYWRDVGTLDAFYDAHMDLVSVHPIFNLYNRRWPIRGETENLAPAKFVQGGLAQESVVGAGCILSAATVRNSVLSSNVMVDSGATVEGSVLMPGVRIGKGAVVRRAILDKNVVVGDGEIIGVDLERDKQRFAVSNGGVVAIGKGVWI
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: MURC_ACIBY
Sequence: MSPTTAANQAKKLIKVPEMRRIKHIHFVGIGGAGMCGIAEVLANQGYKISGSDIKASKTTQQLEENGIKVYIGHEAENIKNANVLVVSTAIDPENPEVKAAIEQRIPIVRRAEMLGELMRYRHGIAVAGTHGKTTTTSLLTTMLAEENLDPTYVIGGLLNSTGVNAALGESRFIVAEADESDASFLYLQPMAAIVTNIDADHMDTYEGSFDKLKDTFVQFLHNLPFYGLAVVCGDDANIREILPRVGRPVITYGFNEDNDIRAIDVEQDGMRSHFTVLRKGREPLRLTINQPGLHNVLNALAAIGVATDEGVSDEAISRALKGFSGVGRRFQVQGEFELGEGNVKLVDDYGHHPKEVEATIKAARQSHPDRRLVMLFQPHRYSRTRDCFDDFIEVLSQVDQLLLLEVYPAGEKPIVGADSRTLARSIRLRGQVEPILIDPVEGNLQNIMQNVLQPNDLLLTQGAGNVGAISVELAQHHLYVK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_ANAMM
Sequence: MVRGDMVLLGVVRAPHGVMGLVKVRTFTEDPSHISAYGPLTDGHNCFNVTVVSVLGADSVIAKFDGLSSRTESEKLRGKRLYVSRSSLPRLQEDEFYENELIGMDAKLEDGTAYGVISAILNFGSCDIIELSTSTGKVVMVPFSRSTFPVVDVERRVVIVVPPEVIGVGSR
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOBA_PSEE4
Sequence: MSTALPLCSILILAGGRGQRMGGRDKGLVSWHGEPLVAHVQHVVREFSDDVVISCNRNQERYALYADQLVSDAEVDFPGPLAGVITGLKVARHEWVVMLACDAPLIDQALIEGLLRLAVEHDSAAMVRQGGYWQPMFSVLPRRVLPMLEHAWAAGERSLQKALLGAVPVQALECAENDQRLSNFNSPELLL
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEP_I83A6
Sequence: MDSNTVSSFQDILMRMSKMQLGSSSEDLNGMITQFESLKLYRDSLGKAVMRMGDLHSLQSRNGNWRRQLSQKFEEIRWLIEEVRHRLKITENSFEQITFMQALQLLLEVEQEMRTFSFQLI
What is the function of this protein?
Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs).  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell.  Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain.  This domain is believed to allow recognition of RNPs bound to the protein M1.  Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized.  Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane.  May down-regulate viral RNA synthesis when overproduced.
What are the official names of this protein?
Nuclear export protein, NEP, Non-structural protein 2, NS2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses NEP family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: TGT_RALPJ
Sequence: MLKYELLTTDGLARRGRMTLNHGVVETPIFMPVGTYGAVKAMSPAELKDIGAQIILGNTFHLWLRPGLEVMDAHKGLHGFNGWDKPILTDSGGFQVFSLGDLRKITEDGVTFASPINGDKLFLSPEISMQIQRRLNSDIVMQFDECTPYKIGDRPATEAEAAASMRMSLRWAQRSRNEFEREKNPNALFAIVQGGMFENLRDESLAGLQAIDADAGGEGFGGYAIGGLSVGEPKEDMMRVLQHVAPRLPADKPHYLMGVGTPEDLVAGVAAGVDMFDCVMPTRNARNGWLFTRFGDIKIKNAVHRNDPRPLDETCGCYTCSNFSRAYLHHLQRVGEILGARLNTIHNLYYYLELMAEMRTAIESHGFAAFQARFAADRARGAL
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: ILVC_CERS4
Sequence: MRVYYDRDCDINLIKDKKVAILGYGSQGHAHALNLRDSGAKNVVVALREGSPSAKKAEAEGLKVMGIAEAAAWCDLIMFTMPDELQAETYRKYVHDNLREGSAIAFAHGLNVHFGLIEPKPGVDVIMMAPKGPGHTVRGEYVKGGGVPCLVAVHNDATGKAMEIGLSYCSAIGGGRSGIIETNFRQECETDLFGEQAVLCGGLVELIRMGFETLVEAGYEPEMAYFECLHEVKLIVDLIYEGGIANMNYSISNTAEYGEYVSGPRILPYEETKARMKAVLTDIQTGKFVRDFMQENAVGQPFFKATRRINDEHQIEQVGEKLRGMMPWISKGKMVDRARN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: PSBL_YUCGL
Sequence: MTQSNPNEQNVELNRTSLYWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RBFA_JANSC
Sequence: MARSKNQNGPSKSQRQLRVGELIRRTLSTVLARADVHDPALNAMSITVAEVRTSSDLKIATVYVMPLGGSGKDEAIEALKRNKGELRRLLGKDLKLKYLPDLRFVIDQTFDQMDATREMLARADVRRDVEKAEDDGPMDGDGA
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_THIDA
Sequence: MMRIAVGLEYRGVGFCGWQSQPQACGVQDAVEKAVSAIAGEAITVTAAGRTDTGVHAALQIVHFDTTSVRPLTAWVRGVNSHLPAGVAVLWAREVDAEFHARFAAFERGYRYVLLNHPVRPGLNAGLVGWHHRPLDVACMNRAASPLIGRHDFSAFRAAECQARSPVKELRRALIERRGDYLLCDFRADGFLHHMVRNLMGCLVQIGAGGRPPEWLHEVLAGRDRTRAAPTFEAAGLYLTHIRYPARFALPESSERWPFA
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: 2AAA_BOVIN
Sequence: MAAADGDDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYDEDEVLLALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAVESLRAISHEHSPSDLEAHFVPLVKRLAGGDWFTSRTSACGLFSVCYPRVSSAVKAELRQYFRNLCSDDTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTELHKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMTQILPCIKELVSDANQHVKSALASVIMGLSPILGKDSTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSLQKIGPILDNSTLQSEVKPVLEKLTQDQDVDVKYFAQEALTVLSLA
What is the function of this protein?
The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit (By similarity).  Upon interaction with GNA12 promotes dephosphorylation of microtubule associated protein TAU/MAPT (By similarity).  Required for proper chromosome segregation and for centromeric localization of SGO1 in mitosis (By similarity).  Together with RACK1 adapter, mediates dephosphorylation of AKT1 at 'Ser-473', preventing AKT1 activation and AKT-mTOR signaling pathway.  Dephosphorylation of AKT1 is essential for regulatory T-cells (Treg) homeostasis and stability (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, Medium tumor antigen-associated 61 kDa protein, PP2A subunit A isoform PR65-alpha, PP2A subunit A isoform R1-alpha.
What is the protein family that this protein belongs to?
Belongs to the phosphatase 2A regulatory subunit A family.
What are the subcellular locations of this protein?
Chromosome, centromere. Nucleus. Cytoplasm. Lateral cell membrane. Cell projection, dendrite. Note=Centromeric localization requires the presence of BUB1.
Protein: IF1_BORAP
Sequence: MDIKEEAIETEGIVKESLPNTMFRVELKNKHIVLAHLSGKMRKHFIKIVPGDKVKVELSPYDLTKGRIVYREK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1344_ACIB3
Sequence: MLAQFDVNLVVLLVLLICGLLSQNAAVTIAAGVLIVIKITPLNQFFPYIQAHGLNLGILILTIGVLTPIASGKLSGESILKSFISFKSLVAIAIGLLVAWLGGRGVKLMSSQPDVVAGLLIGTVAGVALLRGVPVGPLIAAGLLSLFIGK
What are the official names of this protein?
UPF0756 membrane protein ABBFA_001344.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HRK1_YEAST
Sequence: MPNLLSRNPFHGHHNDHHHDRENSSNNPPQLIRSSKSFLNFIGRKQSNDSLRSEKSTDSMKSTTTTTNYTTTNLNNNTHSHSNATSISTNNYNNNYETNHHHNISHGLHDYTSPASPKQTHSMAELKRFFRPSVNKKLSMSQLRSKKHSTHSPPPSKSTSTVNLNNHYRAQHPHGFTDHYAHTQSAIPPSTDSILSLSNNINIYHDDCILAQKYGKLGKLLGSGAGGSVKVLVRPTDGATFAVKEFRPRKPNESVKEYAKKCTAEFCIGSTLHHPNVIETVDVFSDSKQNKYYEVMEYCPIDFFAVVMTGKMSRGEINCCLKQLTEGVKYLHSMGLAHRDLKLDNCVMTSQGILKLIDFGSAVVFRYPFEDGVTMAHGIVGSDPYLAPEVITSTKSYDPQCVDIWSIGIIYCCMVLKRFPWKAPRDSDDNFRLYCMPDDIEHDYVESARHHEELLKERKEKRQRFLNHSDCSAINQQQPAHESNLKTVQNQVPNTPASIQGKSDNKPDIVEEETEENKEDDSNNDKESTPDNDKESTIDIKISKNENKSTVVSANPKKVDADADADCDANGDSNGRVDCKANSDCNDKTDCNANNDCSNESDCNAKVDTNVNTAANANPDMVPQNNPQQQQQQQQQQQQQQQQQQQQHHHHQHQNQDKAHSIASDNKSSQQHRGPHHKKIIHGPYRLLRLLPHASRPIMSRILQVDPKKRATLDDIFNDEWFAAIAACTMDSKNKVIRAPGHHHTLVREENAHLETYKV
What is the function of this protein?
Involved in regulating the activity of the plasma membrane proton pump PMA1.
What are the official names of this protein?
Serine/threonine-protein kinase HRK1, Hygromycin resistance kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TUSD_SALCH
Sequence: MRYAIMVTGPAYGTQQASSALQFAHALLNEGHELASVFFYREGVYNANLLTSPASDEYDLVRAWQKLNTQHGVALNICVAAALRRGIIDETEAGRLALPSANLQPGFTLSGLGALAEASLTCDRVVQF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.  Accepts sulfur from TusA and transfers it in turn to TusE.
What are the official names of this protein?
Sulfurtransferase TusD, tRNA 2-thiouridine synthesizing protein D.
What is the protein family that this protein belongs to?
Belongs to the DsrE/TusD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPD_BURL3
Sequence: MAELATIARPYAEALFRVAEGGDIAAWSTLVQELAQVARLPEVLSVASSPKVTRTQVAELLLAAVKSPLGAGAEAKNFVQMLVDNHRIALLPEIAEQFEALKNEREGAADAEIVSAFPLNGADLESLVSGLERKFKRKLKPTVAVDSSLIGGVRVTVGDEVLDTSVRARLASMQAALTA
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GSHB_XANCP
Sequence: MSLDVVVVMDPIASIKIAKDTTFAMLLEAQRRGHRLHYVRPGGLSLHEGRAVAQVAPLSVREDKASWFTLGAFTELVFGPGQVVLMRKDPPVDAEFIYDTQVLAVAQRAGAQVVNDPQGLRDYNEKLAALLFPQCCPPTLVSRDAAALKAFVLAHGQAVLKPLDGMGGRSIFRSGTGDPNLNVILETLTDGGRKLTLAQRFIPDITAGDKRILLVDGEPVDYCLARIPQGDEFRGNLAAGGRGEGRPLSERDRWIAAQVGPEMKRRGMRFVGLDVIGDYLTEVNVTSPTCVRELDAQFGLNIAGLLFDAIEAGTAQ
What are the official names of this protein?
Glutathione synthetase, GSH synthetase, GSH-S, GSHase, Glutathione synthase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic GSH synthase family.
Protein: ATPF_HELPS
Sequence: MFLVKMVLGFLIFLSPLCATGLDISQTDIIERSLNFLLFAGILWYFLAKKLRSFLHSKSLEISKRLEEIQAQLKVSKENKKKLLKELEQAKEKAELIISDANKEAYTITQKYELQTKMDVENLIKNSKALMDLEVKKIKRELVESVFKDLRESKKVSFNVQDCVNILKQRL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: BHE40_PONAB
Sequence: MERIPSAQPPPACLPKAPGLEHGDLPGMYPAHMYQVYKSRRGIKRSEDSKETYKLPHRLIEKKRRDRINECIAQLKDLLPEHLKLTTLGHLEKAVVLELTLKHVKALTNLIDQQQQKIIALQSGLQAGELSGRNVETGQEMFCSGFQTCAREVLQYLAKHENTRDLKSSQLVTHLHRVVSELLQGGTSRKSSDPAPKVMDFKEKPSSPAKGSEGPGKNCVPVIQRTFAHSSGEQSGSDTDTDSGYGGESEKGDLRSEQLCFKSDHGRRFTMGERIGAIKQESEEPPTKKNRMQLSDDEGHFTSSDLISSPFLGPHPHQPPFCLPFYLIPPSATAYLPMLEKCWYPTSVPVLYPGLNASAAALSSFMNPDKISAPLLMPQRLPSPLPAHPSVDSSVLLQALKPIPPLNLETKD
What is the function of this protein?
Transcriptional repressor involved in the regulation of the circadian rhythm by negatively regulating the activity of the clock genes and clock-controlled genes.  Acts as the negative limb of a novel autoregulatory feedback loop (DEC loop) which differs from the one formed by the PER and CRY transcriptional repressors (PER/CRY loop).  Both these loops are interlocked as it represses the expression of PER1/2 and in turn is repressed by PER1/2 and CRY1/2.  Represses the activity of the circadian transcriptional activator: CLOCK-BMAL1|BMAL2 heterodimer by competing for the binding to E-box elements (5'-CACGTG-3') found within the promoters of its target genes.  Negatively regulates its own expression and the expression of DBP and BHLHE41/DEC2.  Acts as a corepressor of RXR and the RXR-LXR heterodimers and represses the ligand-induced RXRA and NR1H3/LXRA transactivation activity.  May be involved in the regulation of chondrocyte differentiation via the cAMP pathway (By similarity).  Represses the transcription of NR0B2 and attentuates the transactivation of NR0B2 by the CLOCK-BMAL1 complex (By similarity).  Drives the circadian rhythm of blood pressure through transcriptional repression of ATP1B1 in the cardiovascular system (By similarity).
What are the official names of this protein?
Class E basic helix-loop-helix protein 40, bHLHe40, Class B basic helix-loop-helix protein 2, bHLHb2.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly localized in the nucleus (By similarity).
Protein: BIOB_ANADF
Sequence: MCETARTLPPDIVPITVEEARTLIRHTGGPALDALLDRADAVRRAVHGDEVALCGITNAKSGRCPENCGFCSQSAHFPGADAPVYPLVPAEEMVAQAKVAERAGAREFSIVTSGTRVAKESELATIEEAVRKLRAETAVEPCASLGLVREPELVRLKAAGLMHYHHNLETARSFFENVCTTHTYDEQLETIRAAKRQGLKLCSGGILGMGETPEQRVELAATIRELGIDCVPMNFLNPRPGTPMEHVQAITAEECLAAVAVFRLMMPAAHIFVMGGREVNLGGRQHLIFRAGANGTMVGNYLTSAGRGPGETVRMVEEQGLRLRAPDTGREWAFDGSAPAEAEWNRRAAEPGGKRGLPVVGPPRGGCA
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.