PharMolix/UniProtQA huggingface dataset:
Protein: VGLU1_RAT
Sequence: MEFRQEEFRKLAGRALGRLHRLLEKRQEGAETLELSADGRPVTTHTRDPPVVDCTCFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVSMVNNSTTHRGGHVVVQKAQFNWDPETVGLIHGSFFWGYIVTQIPGGFICQKFAANRVFGFAIVATSTLNMLIPSAARVHYGCVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTAFCGSYAGAVVAMPLAGVLVQYSGWSSVFYVYGSFGIFWYLFWLLVSYESPALHPSISEEERKYIEDAIGESAKLMNPVTKFNTPWRRFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGLVSALPHLVMTIIVPIGGQIADFLRSRHIMSTTNVRKLMNCGGFGMEATLLLVVGYSHSKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPIIVGAMTKHKTREEWQYVFLIASLVHYGGVIFYGVFASGEKQPWAEPEEMSEEKCGFVGHDQLAGSDESEMEDEVEPPGAPPAPPPSYGATHSTVQPPRPPPPVRDY
What is the function of this protein?
Multifunctional transporter that transports L-glutamate as well as multiple ions such as chloride, proton, potassium, sodium and phosphate (PubMed:11001057, PubMed:10938000, PubMed:18080752, PubMed:19169251, PubMed:8202535, PubMed:27133463, PubMed:25433636, PubMed:33440152, PubMed:29642010, PubMed:11698619).  At the synaptic vesicle membrane, mainly functions as an uniporter which transports preferentially L-glutamate but also phosphate from the cytoplasm into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells (PubMed:29642010, PubMed:11001057, PubMed:10938000, PubMed:11698619, PubMed:18080752).  The L-glutamate or phosphate uniporter activity is electrogenic and is driven by the proton electrochemical gradient, mainly by the electrical gradient established by the vacuolar H(+)-ATPase across the synaptic vesicle membrane (PubMed:29642010).  In addition, functions as a chloride channel that allows a chloride permeation through the synaptic vesicle membrane that affects the proton electrochemical gradient and promotes synaptic vesicles acidification (PubMed:10938000, PubMed:27133463, PubMed:25433636, PubMed:29642010, PubMed:19169251).  Moreover, may function as a K(+)/H(+) antiport allowing to maintain the electrical gradient and to decrease chemical gradient and therefore sustain vesicular glutamate uptake (PubMed:25433636).  The vesicular K(+)/H(+) antiport activity is electroneutral (PubMed:25433636).  At the plasma membrane, following exocytosis, functions as a symporter of Na(+) and phosphate from the extracellular space to the cytoplasm allowing synaptic phosphate homeostasis regulation (PubMed:33440152, PubMed:8202535, PubMed:29642010).  The symporter activity is driven by an inside negative membrane potential and is electrogenic (PubMed:29642010).  Is necessary for synaptic signaling of visual-evoked responses from photoreceptors (By similarity).
What are the official names of this protein?
Vesicular glutamate transporter 1, VGluT1, Brain-specific Na(+)-dependent inorganic phosphate cotransporter, Solute carrier family 17 member 7.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Cell membrane; Multi-pass membrane protein. Synapse, synaptosome.
Protein: PUR5_CHESB
Sequence: MPIARERKARLENAMSRKKTGLSYADAGVDIDAGNALVEKIKPLVRATRRPGADGEIGGFGGLFDLKAAGFTDPILIAANDGVGTKLKVAIEAGKHDTVGIDLVAMCVNDLVVQGAEPLFFLDYFATGKLDPDQGAAIVAGIAEGCRQAGCALIGGETAEMPGMYRDGDYDLAGFAVGAAERGRLLPTNDIVEGDVILGLASTGVHSNGFSLVRRIVEVSGLDWNDPAPFDSDRSLAEALLTPTRIYVKPILSAIARTHGIKALAHITGGGFPENIPRVLPPAYAAEIDLEAVNVLPVFSWLAERGGVAAQEMLRTFNCGIGMIAVVAAGQAAQVAAVLQKEGEHVEILGSIVPRRDKGVIYQGALEL
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_CITBB
Sequence: MAEKLKVELVTPYKKVLSEEVDEITATGALGEFGVLPGHAPFLTSLKIGELAYRKDGVSHHMALNWGYFEVENDTVTVLVETAEKADEIDLERAKAALGRAETELKGLTPEDKNFRIYEAALERALIRVQVAGKAARR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RSGI1_ACET2
Sequence: MNRLGIIYEIQGMKAVVLTSEGEFLIIRRRKDMKVGQQVSFENEDIYNVRGKRFLYVAAAVSSVAAVLVVMFLYFQSAFLSNTDNIYGYICVDINPSVELVIDETCRVLEVRPQNKDGEQLISGLELLDKNVEDVVYELINRSISFGFVKADDNRKIVLISGALNDKRNELKTKKENDEAELTELLDNIKARVDRIDNIKVRTITATSRERKDALKYGLSMGKYCLYLEAQELNGSITIDEVHDMSISDMIEKLEQMKLALKDEASPKLQTTPTLGGETAQISPESMQHSTVPGLPETPSSSEKTIAPTLHGTPGVPDEKTLQPSTPTESSEYVQDGTKGLKIQYYSRKPHDSAGIDFSFRMFNTGNEAIDLKDVKVRYYFKEDVSIDEMNWAVYFYSLGSEKDVQCRFYELPGKKEANKYLEITFKSGTLSPNDVMYITGEFYKNDWTKFEQRDDYSYNPADSYSDWKRMTAYISNKLVWGIEPN
What is the function of this protein?
Anti-sigma factor for SigI1.  Negatively regulates SigI1 activity through direct interaction (PubMed:20937888).  Binding of the polysaccharide substrate to the extracellular C-terminal sensing domain of RsgI1 may induce a conformational change in its N-terminal cytoplasmic region, leading to the release and activation of SigI1 (Probable).
What are the official names of this protein?
Anti-sigma-I factor RsgI1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: TYY2_RATRT
Sequence: MASDTEKLMCLTTENAEIPADFVELQPLDEIETVSLETNVSQTIEVYGDVGVDWAHGGHYHSPLIALQPLAGSNLSNGDHDQEMIIVQTREEVVDYQDSDNLLLGTEFESQMVLPVTEDDYLQPTTATFSGFMAAENGQDELSPYGGNLCGLTTIIEAGAEEGVNPDLGDKQWEQKQIQIDGLDGEFPFAMWEDNNLKEDPVAEEEAGESTPDYSEYMTGKKFPPEGIPGIDLSDPKQLAEFTSMKPKKPKGDFPRPVACSHKGCGKMFKDNSAMRKHLHIHGPRVHVCAECGKAFVESSKLKRHQLVHTGEKPYQCTFEGCGRRFSLDFNLRTHVRIHTGDKPFVCPFDACNKKFAQSTNLKSHILTHVKNKNDQ
What is the function of this protein?
Functions as a multifunctional transcription factor that may exhibit positive and negative control on a large number of genes.  May antagonize YY1 and function in development and differentiation (By similarity).
What are the official names of this protein?
Transcription factor YY2, Yin and yang 2, YY-2.
What is the protein family that this protein belongs to?
Belongs to the YY transcription factor family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1257_BRADU
Sequence: MTKPPEQDDSNNRIVAVTLDEESIGRSGPDIEHERAIAIYDLIEQNLFAPEGADGKGPFTLHIGITGNRLMFDIRREDGAPVVVHLLSLGPFRGIVKDYFMICDSYYQAIRTATPDKIEAIDMGRRGIHDEGSRTLQERLKGKVRVDFETSRRLFTLITVLHWKG
What are the official names of this protein?
UPF0262 protein blr1257.
What is the protein family that this protein belongs to?
Belongs to the UPF0262 family.
Protein: KUP_BURM7
Sequence: MTDTNHSSMRQHSLQSLAIAAIGVVFGDIGTSPLYSLKEAFSPAHGIPLTPSAILGVISLLFWAIILVVGIKYVLFVMRADNNGEGGVLALMALSLRPLNPKSRITGLMMALGIFGACMFYGDAVITPAISVMSAVEGLEVATPQLSHLVLPITIVILIALFWIQRHGTATVGKLFGPIMLLWFVTIAALGIYHIARAPMIVSAINPYYAFSFMSEHVLLAYVVLGSVVLVLTGAEALYADMGHFGAKPIRLAAYVLVMPSLVLNYFGQGALLLLDPKAIENPFFLLAPQWAALPLVVLSTVATVIASQAVISGAYSLTSQAIQLGYVPRMKILHTSELAIGQIYVPVVNWLLLFVILCIVIGFKSSDNLAAAYGIAVTATMVITTILAAVVMVKVWNWNKLLVAMIIGVFLVIDLGFFGANLLKVEQGGWLPLGIGALLFFLLMTWYKGRHIVKERTAADGIPLAPFLQGLLAHPPHRVSGTAIYLTGNDTLVPVSLLHNLKHNKVLHERTIFMTFVTRDIPYVKDHERVTVHDAGEGLYIVKAEYGFNETPDVKAVLEEVARQRGMTFELMDTSFFLARETVVPTHLPGMSIWRERVFAWMHQNAAKPTDFFAIPANRVVELGTKIEI
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MNMA_AERHH
Sequence: MTDNSQIKVIVGMSGGVDSSVSAYLLQQQGYQVEGLFMKNWEEDDTDEYCSAAQDLADAKAVCDKLGMKLHTINFAAEYWDNVFEHFLEEYKAGRTPNPDILCNKEIKFKAFLEFAAEELGATYIATGHYVRRDDSTGRPRLLRGLDTNKDQSYFLYTLSEAQVGQSLFPVGDLEKPEVRRIAEQLDLITAKKKDSTGICFIGERKFKDFLAKFLPAQPGPIETVDGKVIGEHQGLMYHTLGQRKGLGIGGRKDATEEAWYVVDKEVERNTLVVAQGEHPRLYSDGLIASQLHWVDRTPIRAPRRCTVKTRYRQEDIPCLIQPIDDETIRVIFDEKQAAVTPGQSAVFYDGEVCLGGGIIEQRFSHPV
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMCR5_MACFA
Sequence: MRRCLRVKTRRGQLGLASGCFEQHSCFSPRVNRILSAVQNTPCAGPSSQAPPQPPQASPPAAPDHSRTPSLLASSHSASGGESLFQLYMASLAWPQNCCVLESCRRIPLGGLSSMENRRPLLRKGRLLRGQIHHGQDNQLWGLTGAGALLSG
What are the official names of this protein?
Smith-Magenis syndrome chromosomal region candidate gene 5 protein homolog.
Protein: YNF8_YEAS1
Sequence: MVKKNFIPSVSLVRRDLPTLVTTTTSSTALSKPTSSVVSETSSKSLPSLTSSAFSTSSGATSSSSLIVASITPPSTAGNPFILNAADKPNGTVYIAVGAVIGAIFISILIWWLVSSYLSRRFTMTNSYANDSKNLYRGHHKHSSSLQSNPFDINDEKSYMQDDWDSMSQLESSQYEDAASPFNPIQDPFTDNRRSLFISPTLQVSQYEKSHSRHQSKDTNIFIDDPSLYVGTYLEEEEEEERKLNLNRPQRAASPERKEKKINSMEGYHKRNQSSLGLIPVASATSNTSSPKKAHKRQAPSMFLDDVLNGREII
What are the official names of this protein?
Vacuolar membrane protein SCRG_03194.
What is the protein family that this protein belongs to?
Belongs to the PRM5 family.
What are the subcellular locations of this protein?
Vacuole membrane; Single-pass membrane protein.
Protein: LPXC_VIBVU
Sequence: MIRQRTLKEIVKTTGVGLHSGRKVTLTLRPAAANTGIIYRRTDLTPAVDFPADPASVRDTMLCTALVNDEGVRISTVEHLNAALAGMGIDNIIIEVDAPEIPIMDGSASPFVYLLQQAGIETQNAAKRFIRIKKPVRFEDGDKWAEFVPFNGFRMDFEIEFNHPAIDSDEQRLLFDFSTQGFVREISRARTFGFMRDIEYLQSQNLVLGGSFDNAIVLDDYRILNEEGLRFENEFVTHKVLDAIGDLYMCGHAIIGEFRAYKSGHGLNNQLLRAVLADQEAWEWTTFEEEVGSPVAFAEPNMVLA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: PLMP_PLEOS
Sequence: ATFVGCSATRQTQLNAAASQAQTYAANALSYLNSHTSSTTRYTTWFGTFVTSRYNTVLSHFSSISSNTFSSYTFDCTCSDSGTYAFVNPSNFGYVTLCGAFWNAPVAGTDSRGGTLIHESSHFTRNGGTDDHVYGQAGAQSLARSNPAQAIDNADSHEYFAENNPALA
What are the official names of this protein?
Peptidyl-Lys metalloendopeptidase, MEP, PoMEP.
What is the protein family that this protein belongs to?
Belongs to the peptidase M35 family.
What are the subcellular locations of this protein?
Secreted. Note=Binds strongly to beta-1,3-glucan and chitin, major polysaccharides constituting the fungal cell wall.
Protein: CLD11_MACFA
Sequence: MVATCLQVVGFVTSFVGWIGVIVTTSTNDWVVTCGYTIPTCRKLDELGSKGLWADCVMATGLYHCKPLVDILILPGYVQACRALMIAASVLGLPAILLLLTVLPCIRMGHEPGVAKYRRAQLAGVLLILLALCAIVATIWFPVCAHRETTIVSFGYSLYAGWIGAVLCLVGGCVILCCAGDAQAFGENRFYYSSGSSSPTHAKSAHV
What is the function of this protein?
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
What are the official names of this protein?
Claudin-11.
What is the protein family that this protein belongs to?
Belongs to the claudin family.
What are the subcellular locations of this protein?
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.
Protein: HSLU_CAUVN
Sequence: MTEFSPREIVSELDRYIVGHAEAKKAVAVALRNRWRRRRVPADLRDEVTPKNILLIGPTGVGKTEIARRLAKLAQAPFLKVEATKFTEVGYVGRDVDQIVRDLVESALAMVREKRRAAVKAKAEGGAEERILDALTGPGSTAARESFRKKLRAGELDDKEVELQLADTGGPSFDIPGQPGAAVFNLSDMMKSLGGGRTKTHKTTVSGAWAPLIAEESDKLLDQEALTQEALELAENHGIVFLDEIDKVASSSQRSGADVSREGVQRDLLPLIEGTTVSTKYGPVKTDHILFIASGAFHVAKPSDLLPELQGRLPIRVELKGLSRDDMRRILTEPEANLIRQHQALMATEEVTLVFTDEAIDALADAAVAVNGSVENIGARRLQTVMEKVVEEISFTAADRGGETVTIDAAYVQERVGALAANADLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDGC_ECO57
Sequence: MLWFKNLMVYRLSREISLRAEEMEKQLASMAFTPCGSQDMAKMGWVPPMGSHSDALTHVANGQIVICARKEEKILPSPVIKQALEAKIAKLEAEQARKLKKTEKDSLKDEVLHSLLPRAFSRFSQTMMWIDTVNGLIMVDCASAKKAEDTLALLRKSLGSLPVVPLSMANPIELTLTEWVRSGSAAQGFQLLDEAELKSLLEDGGVIRAKKQDLTSEEITNHIEAGKVVTKLALDWQQRIQFVMCDDGSLKRLKFCDELRDQNEDIDREDFAQRFDADFILMTGELAALIQNLIEGLGGEAQR
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: BIPA_BUCBP
Sequence: MQKKTNKNLRNIAIIAHVDHGKTTLVDKLLQQSGTFKKHEEFSERIMDSNDLEKERGITILAKNTAIQWKKYRINIIDTPGHADFGGEVERILSMVDSVLLVVDALEGPMPQTRFVTQKAFSYGIKPIVVINKIDRKHARPNWVIDQIFDLFVNLNATDEQLDFPTIYTSALLGTSGVSYNHMNPDMIPLYNAIVKYTPPPTVYPNCPFQMQISQLDYDNYLGIIGIGRINKGSVTSNQSISIINNTEVKRTGKIGKILQYLGLNKIEINEAQSGDIIAITGIDKLNISDTICDPQYISALPMLKIDEPTVEMLFSVNKSPFSGTEGKYITSRQIFNRLKKEENYNVALKIKETNDTNTFSVSGRGELHLSILIENMRREGFELEVSRPQVILKTINELIQEPMETVVLDIENKYQGTIMKTIGQRKGTISNITPDQNNERTRLDCIISSRSLIGFRTEFSTLTSGSGLFYSTFSHYQKIESNKIKRHRNGVLIANKTGQAIGFSLFNLQNRGKLFITHGTKVYEGQIVGIHNRVNDLTVNCLSGKKLTNMRASGSDEAITLTTPIKMTLEYAISFINDDELVEITPKSIRLRKRYLKENERKILLRNIKE
What is the function of this protein?
A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation.  Binds GTP and analogs.  Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
What are the official names of this protein?
50S ribosomal subunit assembly factor BipA, GTP-binding protein BipA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Binds to ribosomes.
Protein: NU2C1_PANGI
Sequence: MIWHVQNENFILDSTRIFMKAFHLLLFDGSLIFPECILIFGLILLLMIDSTSDQKDIPWLYFISSTSLVMSITALLFRWREEPMISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDLITIFVAPECFSLCSYLLSGYTKKDVRSNEATMKYLLMGGASSSILVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGIGFKLSPAPSHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNDGYASMITYMLFYISMNLGTFACIVLFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGLPPLAGFFGKLYLFWCGWQAGLYFLVLIGLLTSVVSIYYYLKIIKLLMIGRNQEITPHVRNYRRSPFRSNNSIELSMIVCVIASTIPGISMNPIIAIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 A, chloroplastic, NAD(P)H dehydrogenase, subunit 2 A, NADH-plastoquinone oxidoreductase subunit 2 A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RL20_DESHD
Sequence: MARVKRGVTKHQRHKKVLKLAKGFRGAKSKLYRPANEQVMKSLAYAYAHRRDKKGDFRKLWIARINAAARLNGLSYSRMMNGLKIAGVSVNRKMLADLAINDAAAFTELVNVAKAQVSAK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: Y9248_DICDI
Sequence: MTIIFLICLDASTQSTTNNSINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSKVFDFNIF
What are the official names of this protein?
Putative uncharacterized protein DDB_G0277445.
What are the subcellular locations of this protein?
Secreted.
Protein: PSBF_TAXBR
Sequence: MTIDRTYPIFTVRWLAVHGLAVPTVFFLGSISAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: KDSB_YERPA
Sequence: MSFIAIIPARYASTRLPGKPLADIAGKPMVVHVMERALASGADRVIVATDHPDVVKAVEAAGGEVCLTRADHQSGTERLAEVIEHYGFADDDIIVNVQGDEPLVPPVIIRQVADNLAACSAGMATLAVPIASSEEAFNPNAVKVVMDAQGYALYFSRATIPWERERFAQSKETIGDCFLRHIGIYAYRAGFIRRYVNWAPSQLEQIELLEQLRVLWYGEKIHVAVAKAVPAVGVDTQSDLDRVRAIMLNQ
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OSPG_SHIFL
Sequence: MKITSTIIQTPFPFENNNSHAGIVTEPILGKLIGQGSTAEIFEDVNDSSALYKKYDLIGNQYNEILEMAWQESELFNAFYGDEASVVIQYGGDVYLRMLRVPGTPLSDIDTADIPDNIESLYLQLICKLNELSIIHYDLNTGNMLYDKESESLFPIDFRNIYAEYYAATKKDKEIIDRRLQMRTNDFYSLLNRKYL
What is the function of this protein?
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues.  This protein is a kinase that is involved in down-regulation of the host innate response induced by invasive bacteria.  Prevents or at least delays host phospho-NF-kappa-B inhibitor alpha (NFKBIA) degradation.  Does not phosphorylate E2 enzymes.
What are the official names of this protein?
Protein kinase OspG, Effector protein OspG.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily.
What are the subcellular locations of this protein?
Secreted. Host cell. Note=Secreted via Mxi-Spa type III secretion system (TTSS), and delivered into the host cell.
Protein: NRAM_I72A3
Sequence: MNPNQKIITIGSVSLTIATICFLMQIAILVTTVTLHFKQYECDSPANNQVMPCEPIIIERNITEIVYLTNTTIEKEICPKLVEYRNWSKPQCKITGFAPFSKDNSIRLSAGGDIWVTREPYVSCDPGKCYQFALGQGTTLDNKHSNDTIHDRTPHRTLLMNELGVPFHLGTRQVCIAWSSSSCHDGKAWLHVCVTGYDKNATASFIYDGRLVDSIGSWSQNILRTQESECVCINGTCTVVMTDGSASGRADTKILFIEEGKIVHISPLSGSAQHVEECSCYPRYPGVRCICRDNWKGSNRPVVDINVKDYSIDSSYVCSGLVGDTPRNNDRSSNSYCRNPNNEKGNHGVKGWAFDDGNDVWMGRTISEDSRSGYETFKVIGGWSTPNSKLQINRQVIVDSDNRSGYSGIFSVEGKSCINRCFYVELIRGREQETRVWWTSNSIVVFCGTSGTYGTGSWPDGADINLMPI
What is the function of this protein?
Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates.  Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release.  Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell.  Otherwise, infection would be limited to one round of replication.  Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors.  May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells.  Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport.  May additionally display a raft-association independent effect on budding.  Plays a role in the determination of host range restriction on replication and virulence.  Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
What are the official names of this protein?
Neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 34 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type II membrane protein. Note=Preferentially accumulates at the apical plasma membrane in infected polarized epithelial cells, which is the virus assembly site. Uses lipid rafts for cell surface transport and apical sorting. In the virion, forms a mushroom-shaped spike on the surface of the membrane.
Protein: SAT_STAES
Sequence: MSNNETITNYTIKPHGGELINRVVEGNERERLIEEALKFKPITLNPWGISDLELIGIGGFSPLTGFMNKEDYTKVIEETHLSNGLVWSIPITLPVTESEADKLEIGDDIALYGEDGQLYGTLKLEEKYTYDKEKEARLVYGTTEEAHPGVKKVYEKGNIYLGGPIKLLNRPKHDAFSNYHLDPSETRQLFHDLGWKTVVGFQTRNPVHRAHEYIQKSALEIVDGLLLNPLVGETKSDDIPADVRMESYEVILKNYYPEDRARLVIYPAAMRYAGPREAILHATVRKNYGCTHFIVGRDHAGVGDYYGTYEAQELITQFEDELGIQILKFEHAFYCEACGNMATAKTCPHDASQHLHLSGTKVREKLRNGESLPTKFSRPEVAEVLIKGLREK
What are the official names of this protein?
Sulfate adenylyltransferase, ATP-sulfurylase, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the sulfate adenylyltransferase family.
Protein: PSBJ_CYAM1
Sequence: MASTGRIPLWLVATIGGIAVLTVLGLFFYGSYSGLGSSL
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein J, PSII-J.
What is the protein family that this protein belongs to?
Belongs to the PsbJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CM34_CONPE
Sequence: DDNPGGASGKFMNVLKGQPLCCPFGGCHELCHCCGS
What are the official names of this protein?
Conotoxin PnMLKMF-01.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TRUB_PASMU
Sequence: MAKPRKRGRDIDGVFLLDKPQGMSSNDIMQKVKRVFQANKAGHTGALDPLATGMLPICLGEATKFSQFLLDADKRYQVTAKLGERTDTSDAEGQVVETRDVQVDVQDILAALPHFRGNLMQVPTMFSALKHQGKPLYEYARAGITVEREARPITIFDLQFIAYDAPYLTLEVHCSKGTYIRTLVDDLGEYLGCGAHVTVLRRTAVANYPVEAMMNWDTLQVLAAQQDLALLDQHLLPTDSAVSALPALHLNQEQSKAISFGQRVKFDNPTQLTGQVRLFSDTQQFLGVALVDEHNVIRPQRLMTQNT
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.