PharMolix/UniProtQA huggingface dataset:
Protein: ATPG_LACLA
Sequence: MGASLNEIKTKIASTKKTSQITGAMQMVSAAKLQKAESHAKAFQIYAEKVRKITTDLVSSDKEPAKNPMMIKREVKKTGYLVITSDRGLVGGYNSNILKSVMNTIRKRHANESEYTILALGGTGADFFKARNVKVSYVLRGLSDQPTFEEVRAIVTEAVTEYQAEEFDELYVCYNHHVNSLVSDARMEKMLPISFEESGQQKPSLETFELEPDRETILNQLLPQYAESMIYGSIVDAKTAEHAAGMTAMRTATDNAHSVINDLTIQYNRARQASITQEITEIVAGASAL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: FBLN5_BOVIN
Sequence: MPGFKRILTVTVLALCLPTPGNAQQQCTNGFDLDRSSGQCLDVDECRTIPEACRGDMMCVNQNGGYLCIPRTNPVYRGPYSNPYSNPYSASYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWLLEGQCLDIDECRYGYCQQLCANVPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQTCVNTYGSFICRCDPGYELEDDGVHCSDMDECSFSEFLCQHECVNQPGTYFCSCPAGYILLDDNRSCQDINECEHRNHTCILQQTCYNLQGGFKCIDPIRCEEPYLRISDNRCMCPAENPGCRDQPFTILYRDMDVVSGRSVPADIFQMQATTRYPGAYYIFQIKSGNDGREFYMRQTGPISATLVMTRPIKGPRDIQLDLEMITVNTVINFRGSSVIRLRIYVSQYPF
What is the function of this protein?
Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN.  Stabilizes and organizes elastic fibers in the skin, lung and vasculature.  Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif.  Vascular ligand for integrin receptors which may play a role in vascular development and remodeling.  May act as an adapter that mediates the interaction between FBN1 and ELN.
What are the official names of this protein?
Fibulin-5, FIBL-5.
What is the protein family that this protein belongs to?
Belongs to the fibulin family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space, extracellular matrix. Note=co-localizes with ELN in elastic fibers.
Protein: RYA_TRICA
Sequence: MHARKLIVVLVYILTVLVSVAVSKRYTSEKRVQNLATFKTMMRYGRGGPSPNNKENKVNIRPRADAFFLGPRYGKRSGWSPNASLVYPVSTPLCGLDEDLSCAYTGISDLYRCTPRKGESEEFTTSSN
What is the function of this protein?
Neuropeptides RYamide-1 and RYamide-2 are ligands for the G-protein coupled receptor RYa-R.  RYamide-2 is the most potent activator of RYa-R.
What are the official names of this protein?
RYamide neuropeptides.
What are the subcellular locations of this protein?
Secreted.
Protein: SEPF_NOSS1
Sequence: MNNIFSKLRDFVGLNEQVEYEYYEEEADTDNYQNLYQQENPQPAPAEAAPNNRRWREPMTTMGDDVAAGTKSAMGNVIGMPGAINGISEVLVLEPRTFEEMPQAIQALRERKSVVLNLTIMDPDQAQRAVDFVAGGTYALDGHQERIGESIFLFTPSCVQVSTQGGVIHEVPQPPARPARPASTNPPAWGNETNRMAQ
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: TEG4_HHV2H
Sequence: MELSYATTLHHRDVVFYVTADRNRAYFVCGGSVYSVGRPRDSQPGEIAKFGLVVRGTGPKDRMVANYVRSELRQRGLRDVRPVGEDEVFLDSVCLLNPNVSSERDVINTNDVEVLDECLAEYCTSLRTSPGVLVTGVRVRARDRVIELFEHPAIVNISSRFAYTPSPYVFALAQAHLPRLPSSLEPLVSGLFDGIPAPRQPLDARDRRTDVVITGTRAPRPMAGTGAGGAGAKRATVSEFVQVKHIDRVVSPSVSSAPPPSAPDASLPPPGLQEAAPPGPPLRELWWVFYAGDRALEEPHAESGLTREEVRAVHGFREQAWKLFGSVGAPRAFLGAALALSPTQKLAVYYYLIHRERRMSPFPALVRLVGRYIQRHGLYVPAPDEPTLADAMNGLFRDALAAGTVAEQLLMFDLLPPKDVPVGSDARADSAALLRFVDSQRLTPGGSVSPEHVMYLGAFLGVLYAGHGRLAAATHTARLTGVTSLVLTVGDVDRMSAFDRGPAGAAGRTRTAGYLDALLTVCLARAQHGQSV
What is the function of this protein?
May participate in DNA packaging/capsid maturation events.  Promotes efficient incorporation of tegument proteins UL46, UL49, and US3 into virions.  May also play a role in capsid transport to the trans-Golgi network (TGN) (By similarity).
What are the official names of this protein?
Tegument protein UL21.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae UL21 protein family.
What are the subcellular locations of this protein?
Virion tegument. Host cytoplasm. Host nucleus.
Protein: PTH_STRU0
Sequence: MVKMIVGLGNPGSKYDNTKHNIGFMAIDTIVKNLDINFTEEKNFKALVGSTFINQEKIYFVKPVTFMNNSGIAVKALLTYYNISIQDLIVIYDDLDMEVGKIRFRQKGSAGGHNGIKSIISHIGTQEFDRIKIGIGRPKQGMTVINHVLGKFDQDDDITIKNTLNKVDNAVNYYLQMKNFEKTMQKYNG
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS8_SYNE7
Sequence: MLPFLRSELARCQPYHPNPGGTGMAMDILDTNECPYDLPTDLKQTLADRYVEAIASNRYPDGSHTDLKAAIVDYLSEQTAGQWQPGPEHVTVGNGSDELIRSILIATCLGGQGSVLVAEPTFSMYGIVAETLGIPVVRIGRDPQTWEMDLAAAETAITQTEGTPVRLCFVVHPNSPTANPLTEAEKDWLRQVPPQILVVIDEAYFEFSGETLLAELPQHPNWLITRTFSKALRLAAHRVGYGIGDPQLIAALEAIRLPYNLPSVAQLAATLALEARSQLLSAIPRLITERDRLYRKLQVVSQLQVWPSASNFLFLKTQSSSQTAALAAQLKAQGTLVRHTADGLRITIGSPAENERTLAHLQTAITQSLPATV
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: KINI4_PERAM
Sequence: GAQFSSWG
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Kinin-4, Pea-K-4.
What is the protein family that this protein belongs to?
Belongs to the kinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL15_CHLT3
Sequence: MNLSTLQPAKGAIKSGRRIGRGQGSGSGTTAGRGNKGHKARSGYTSKNFEGGQMPLHRRLPKFGFSVPNPVKIRTVNVADLEKYVEKGLLEKEITLESFKSIGIIGKKDRLKVLGTGEVSSALTVTAHYFSESAKEKIEKAGGKTVVVFRTIEEAQKMKKELFEEALLTPKVSVDEKKKAAKKLKA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: ASP5_TOXGO
Sequence: MEAGAMGGSSFLSFSSGPSAETSPSSLSPPTSSSPSPSPQLVSDSVESLHAKRPLAQSSRSSSRTAASTCFCWQGEGQENEAAPTISQEERRGGSMTAASAGHLETAREEAARCLGCSYTGEERRGASSATSVLSLGGERGRPPSRSSSLWTFSGLLSPLAFRSRRCCPQFSSSSSPLSPLPHPRGAPASACGSAVITDRAGRPASPLSFSRLASPVSDPSGVCPPRVVAARVWRLLSSVLFSLVNCARLFPRRLSRRPDPLRKPRAQVWSASSRSLQALLLATVALFAACSSLHGSSLLGAQAASPTPPFLSLSSSPRSLASDSAKKGSNAPEQSREQRGEREGERQRPDKGEENGETEETFPAASGVVPAPGLKVADLPRTGPPVDLLGLPIRKKVFRARLYGSMFSYAYYFLDILVGTPPQRASVILDTGSSLLAFPCAGCSECGQHLDPAMDTSRSATGEWIDCKEQERCFGSCSGGTPLGGLGGGGVSSMRRCMYTQTYSEGSAIRGIYFSDVVALGEVEQKNPPVRYDFVGCHTQETNLFVTQKAAGIFGISFPKGHRQPTLLDVMFGHTNLVDKKMFSVCISEDGGLLTVGGYEPTLLVAPPESESTPATEALRPVAGESASRRISEKTSPHHAALLTWTSIISHSTYRVPLSGMEVEGLVLGSGVDDFGNTMVDSGTDLSSIFPPIKVSFGDEKNSQVWWWPEGYLYRRTGGYFCDGLDDNKVSASVLGLSFFKNKQVLFDREQDRVGFAAAKCPSFFLDQRPRGPDSGDGPKGRPTAPFTVPPLRVPVPMDGGGVPGDAKQPEGLPLSPQQLWVAAALVVVAILIAVTVILLHTIKRPSRSSAVVPAPSAPRLPFAQNSKSAGRFARGLGHGALGVGNPVYVQRTQRYREVQEAQPHTADAYYDVEEDRFTGEDDGDFFGDDSVPSAEEQETAPSLSLREESSPFSASQSTLLDLPLGGE
What is the function of this protein?
In tachyzoites, plays an essential role in the export of several dense granule proteins into the host cell by cleaving the localization motif RRLxx (termed Toxoplasma export element (TEXEL)) located downstream of the N-terminal secretory signal sequence (PubMed:26576949, PubMed:26473595, PubMed:26270241, PubMed:30377279).  However, can also regulate the export of proteins that lack the TEXEL motif, such as GRA24 (PubMed:26576949, PubMed:26473595, PubMed:26270241).  Requires Arg at P3 and P2, and Leu at P1 in the substrate TEXEL motif and, specifically, cleaves after Leu (PubMed:26576949).  Cleaves GRA16; proteolytic cleavage is essential for the correct trafficking of GRA16 from the parasite into the infected host nucleus (PubMed:26576949, PubMed:26473595, PubMed:26270241).  Cleaves GRA19 and GRA20 (PubMed:26473595).  Cleaves MYR1 (PubMed:26576949).  Cleaves LCAT, GRA44, GRA46, GRA46, ROP35/WNG1 and ROP34/WNG2 (PubMed:30377279).  By regulating the export of dense granule proteins into the host cell, regulates multiple processes during tachyzoite infection of host cells, including recruitment of host mitochondria to the parasitophorous vacuole (PV), formation of the nanotubular network (NTN) or intravacuolar network (IVN) which are membranous tubules that bud from the PV membrane into the vacuolar lumen and, up-regulation of host cell genes to facilitate the parasite infection and modulate the host innate immune response (PubMed:26576949, PubMed:26473595).  At the bradyzoite stage, also involved in the formation of the cyst wall (PubMed:26473595).
What are the official names of this protein?
Aspartic protease 5.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
Protein: SEPF_STAS1
Sequence: MALKDLFSGFFVVEEEDDELEAPPEENEQQERQQPKQQAQSQNQFTEQPRNVNSERPRSIQSVPKKQSTRLQQSSGERKYQMNNTTSKNNARNVVNMNNQEQENYDFTQESSKMCLFEPRVFSDTQDIADELKNRRATLVNLQRIDKVSAKRIIDFLSGTVYAIGGDIQRVGSDIFLCTPDNVEVAGSITDQIENMEYQGE
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: HOPD_SALTY
Sequence: MFVALPFLIFYASFSLLLGIYDARTGLLPDRFTCPLLWGGLLYHQICLPERLPDALWGAIAGYGGFALIYWGYRLRYQKEGLGYGDVKYLAALGAWHCWETLPLLVFLAAMLACGGFGVALLVRGKSALINPLPFGPWLAVAGFITGWKVFFPDG
What are the official names of this protein?
Leader peptidase HopD.
What is the protein family that this protein belongs to?
Belongs to the peptidase A24 family.
Protein: M7E_CONCN
Sequence: MKLTCVVIVAVLLLTACQLITADDSRGTQKHRALRSDTKLSMSTRCKGTGKPCSRIAYNCCTGSCRSGKCG
What is the function of this protein?
Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels (Cav).
What are the official names of this protein?
Omega-conotoxin-like CnVIIE.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1281_METTH
Sequence: MAKNVLDLLMWHPKWDIERCRISYLHRGACRNLKTIRGSDIERLERGFMILRDGSSIPYHRVVKIVCDNSFIWKKQKKGIG
What are the official names of this protein?
UPF0248 protein MTH_1281.
What is the protein family that this protein belongs to?
Belongs to the UPF0248 family.
Protein: MSCL_BURL3
Sequence: MSIIKEFKEFAVKGNVMDLAVGVIIGGAFSKIVDSVVKDLIMPVIGVLTGGLDFSNKFVLLGTIPPTFKGNPDSFKDLQAAGVAAFGYGSFITVAINFVILAFIIFLMVKFINKLRKPEEAAPAATPEDTVLLREIRDSLKQR
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RPOC_TROWT
Sequence: MSTSFKEIRVSMATTEDIRRWSYGVVKKPETINYRTLKPEKDGLFGEQIFGPTRDWECGCGKYKRSRYRGVVCERCGVEVTQSSVRRERMGHIELAAPVTHIWYFKGVPSRLGYLLDIAPKDLDKVIYFAAYMVVSLDEEGRKEDLQDLENELRLDIKQLRDACDASIASAVSELERTITELQDAKTSASRINKVRSEAENKMANIRREYDDKIEHLERVWDSFKALKVGGLYAEDDVFRDVQDRYGDYFDACMGAEAIKRRLEDFDLQKTAQELGVQIVECRGQRKVRAIKRLRVVNSFITSKANPACMVLDVIPVIPPELRPMVQLDAGRFAASDLNDLYRRVINRNNRLKRLLDLGAPRIIVNNEKRMLQEAVDALFDNGRRGRPVSGTNNRTLKSLSDMLKGKSGRFRQNLLGKRVDYSGRSVIVVGPTLQLHQCGLPKLMALELFKPFIVKRLLDLALAPNIRSARRMIERGDPAVWDMLDAVIKARPVLLNRAPTLHRLGIQAFEPQLVEGKAIQLHPLVCAAFNADFDGDQMAVHLPLSLEAQAEARVLMLASNNILNPSDGRPVTLPSHDMIIGLYHLTTVKPSAKGAGRAFSSVAEAIMAKDRGDLSISAPVKILFSNIVLDGKTLDSAVVETTLGRAIFNEALPDGHPYINELVDKQVISSIINNLAEVYSKVEVANTLDKIKSVGFHWATRSGVTVAISDVVSPPEKQEIISKYEAQARGVQQDFEIGLLTDLERRQALVSIWSEATDRVAEAMRKCFPDDNTINTMVTSGARGNWLQVRNIAGMRGLVANPKGETIPRPIISSYREGLSVTEYFISTHGARKGLVDTALKTADSGYLTRRLVDVAQDVVVRERDCGFTRGVRMPVTFRGDDGELHKVENAEHSVYGRTLAEDVKTPDDNLIAKAGEDISGIMIDSFIAAGVESVEVRSVLTCRSKVGVCSACYGRSLATGARVDIGDAVGIVAAQSIGEPGTQLTMRTFHSGGSASAVDITQGLPRVQELFEARTPRAAAPIAEADGTVSIEDGDRARRLILKSDNNEEFSYTVLKRAQLRVKDGSRVSLGDQLVEGSLDPKEVLRVKGIRAVQEYLVNGVQQVYRSQGVPIHNKHIEVIVRQMLRKVTVVDHGDTSMLPGELIDQSRYQELNREAQAEGRKTASARQEVTGITKASLATESWLSAASFQETTRVLTQAVISGRRDPLIGLKENVIIGNLIPAGTGLSVYRDVEPEPRPEAISRMYPTRRPEIENLLEGDSVDPEFDFSSLTQGLELPDDYPVQ
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: RUVB_RHILW
Sequence: MSEPARLISPEKRGEDLDITLRPQSLDEFTGQAEARANLKVFIEAAKNRGEALDHVLFVGPPGLGKTTLAQIMAKELGVNFRSTSGPVIAKAGDLAALLTNLEERDVLFIDEIHRLNPAVEEILYPAMEDFQLDLIIGEGPAARSVKIDLSKFTLVAATTRLGLLTTPLRDRFGIPVRLSFYTVEELELIVRRGARLMNLPITEEGAREIARRARGTPRIAGRLLRRVRDFAEVARAEAVTREIADEALTRLLVDNVGFDQLDKRYLNMIAVNFGGGPVGIETIAAGLSEPRDAIEDIIEPYMIQQGFIQRTPRGRVLTAIAWKHLGMQPPKEMEAAQFRLFQEDN
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: RRG1_YEAS6
Sequence: MAQNFGKIPSHKSYVLSLYRTVLRNIPKCCHSYAFQYEIKKTLSKQLFKHKHDKSSWSVYTLLNEFSLLNNCLLEGKLQEIKNLMKPLKKMKKQLETTKILNSLTSLGDVKTNDPEEVRRFHVLSAYIKRKQDLGLLPAYIPKTYQHKLLLPLALNEHACLKLFHIQQKLKNGPPSAGLSYTKEGRNQIWFVRSPINKGRQQSKKLGILIRKERKDSQKNIDNLNFCEINAAWALHEAIWEEYLESKKIIKVNLPKYLEYAANIPKSTKCNPSSQYQKIKEWVDPVREIMFELHSKSFQRVEYFNKYKEKLLKNGGQLAYFDKKSKEMYAKRLTLFRKMSKETLPYVTLFIEGRDLPSVLAKYGF
What is the function of this protein?
Essential for respiratory growth and required for mitochondrial protein synthesis.  Required for vacuolar acidification (By similarity).
What are the official names of this protein?
Required for respiratory growth protein 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RRG1 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: HSCA_BURMS
Sequence: MALLQISEPGMAPAPHQRRLAVGIDLGTTNSLVAAVRNSIPEALPDDAGRVLLPSVVRYLDKGGRRIGHAAKEEAAIDPRNTIVSVKRFMGRGKAEVEGAANAPYEFVDAPGMVQIRTVDGVKSPVEVSAEILATLRQRAEDTLGDDLVGAVITVPAYFDDAQRQATKDAARLAGLNVLRLLNEPTAAAIAYGLDNGAEGLYAVYDLGGGTFDLSILKLTKGVFEVLAAGGDSALGGDDFDHLLFEHVLAQAGLEVAALAPEDVRLLLDRVRGAKEALSAAPQARVDVKLSTGEKLAQTITRDTFAALVEPLVQRTLGPTRKALRDAQVSAADIKGVVLVGGATRMPVIRDAVAKYFGQPPLVNLDPDQVVALGAAIQADLLAGNRSGGDDWLLLDVIPLSLGVETMGGLVEKIIPRNSTIPVARAQEFTTFKDGQTAMAIHVVQGERELVSDCRSLARFELRGIPPMTAGAARIRVTYQVDADGLLSVFAREQHSGVEASVVVKPSYGLGDDDIARMLEDSFKTAEVDMRARALREAQVEAQRLVEATEAALVADGDLLDASERATVDALVASLRALAPGDDADAIDTATKALAEGTDEFAARRMDKSIKRALAGRKLDEI
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: TRUB_STRAW
Sequence: MTEKHRTPDGLVIVDKPSGFTSHDVVAKMRGIARTRRVGHAGTLDPMATGVLVLGVEKATKLLGHLALTEKEYLGTIRLGQNTLTDDAEGEIISSTDASRVTRDAIDAGVAKLSGAIMQVPSKVSAIKIDGVRSYKRAREGEDFEIPARPVTVSSFAVYDVRDAVAEDGTPVLDLVVSVVCSSGTYIRALARDLGADLGVGGHLTALRRTRVGPYKLDAARTLDQLQEELTVMPIAEAAAAAFPRWDVDTKRARLLLNGVRLEMPEEYAGRGAVAVVDPAGRFLALVEEQKGKAKSLAVFG
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: PP324_ARATH
Sequence: MLLVMVRSSTISPKSLRLYCSGHIIDSLRHSISRWNSPSGYCSNYYFSKRKHKRHFTSSVLSPVTPIVHNLFDELPERENRTMESSFMFLRDVLRSFMMRTETETPRSVHCFALKCGLLQDLATSSKLLTFYGRTGELVSSSCLFDELKEKDVIVWNSMITALNQNGRYIAAVGLFIEMIHKGNEFDSTTLLLAASALSSLHLSRKCSMLHCLAIETGLVGDSSLCNALMNLYAKGENLSSAECVFTHMEHRDIVSWNTIMTKCLANGHPRKSLQYFKSMTGSGQEADTVTFSCVISACSSIEELTLGESLHGLVIKSGYSPEAHVSVGNSIISMYSKCGDTEAAETVFEELVCRDVISSNAILNGFAANGMFEEAFGILNQMQSVDKIQPDIATVVSITSICGDLSFSREGRAVHGYTVRMEMQSRALEVINSVIDMYGKCGLTTQAELLFKTTTHRDLVSWNSMISAFSQNGFTHKAKNLFKEVVSEYSCSKFSLSTVLAILTSCDSSDSLIFGKSVHCWLQKLGFGDNMLSANSVINMYIGCRDLTSAFLRLETMSETRDLTSWNSVISGCASSGHHLESLRAFQAMSREGKIRHDLITLLGTISASGNLGLVLQGRCFHGLAIKSLRELDTQLQNTLITMYGRCKDIESAVKVFGLISDPNLCSWNCVISALSQNKAGREVFQLFRNLKLEPNEITFVGLLSASTQLGSTSYGMQAHCHLIRRGFQANPFVSAALVDMYSSCGMLETGMKVFRNSGVNSISAWNSVISAHGFHGMGEKAMELFKELSSNSEMEPNKSSFISLLSACSHSGFIDEGLSYYKQMEEKFGVKPVTEHRVWIVDMLGRAGKLREAYEFITGIGEPQKAGVWGALLSACNYHGDTKLGKEVAEVLFEMEPDNASYYISLANTYVGLGGWEEAVRLRKMVEDNALKKLPGYSVIDVRCLDTVS
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At4g19220, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PPR family. PCMP-E subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CH60_SERFI
Sequence: MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQSIITEGLKAVAAGMNPMDLKRGIDKAVVAAVEELKKLSVPCSDSKAIAQVGTISANSDETVGKLIAEAMEKVGKEGVITVEEGTGLQDELDVVEGMQFDRGYLSPYFINKPETGSVELESPFILLADKKISNIRELLPVLEAVAKAGKPLLIVAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTAGTVISEEIGLELEKATLEDLGQAKRVVINKDTTIIIDGVGDEATIQGRVTQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVAGKIAGLKGDNEDQNVGIKVALRAMESPLRQIVINAGEEASVIANNVKAGEGSYGYNAYSEEYGDMIAMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPKADAPDLXGAGGMGG
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIR1E_MOUSE
Sequence: MAEHGESSEDRISEIDYEFLPELSALLGVDAFQVAKSQEEEEHKERMKMKKGFNSQMRSEAKRLKTFETYDTFRSWTPQEMAAAGFYHTGVRLGVQCFCCSLILFGNSLRKLPIERHKKLRPECEFLQGKDVGNIGKYDIRVKRPEKMLRGGKARYHEEEARLESFEDWPFYAHGTSPRVLSAAGFVFTGKRDTVQCFSCGGSLGNWEEGDDPWKEHAKWFPKCEFLQSKKSSEEIAQYIQSYEGFVHVTGEHFVKSWVRRELPMVSAYCNDSVFANEELRMDMFKDWPQESPVGVEALVRAGFFYTGKKDIVRCFSCGGCLEKWAEGDDPMEDHIKFFPECVFLQTLKSSAEVIPTLQSQYALPEATETTRESNHGDAAAVHSTVVDLGRSEAQWFQEARSLSEQLRDNYTKATFRHMNLPEVCSSLGTDHLLSCDVSIISKHISQPVQEALTIPEVFSNLNSVMCVEGETGSGKTTFLKRIAFLWASGCCPLLYRFQLVFYLSLSSITPDQGLANIICAQLLGAGGCISEVCLSSSIQQLQHQVLFLLDDYSGLASLPQALHTLITKNYLSRTCLLIAVHTNRVRDIRLYLGTSLEIQEFPFYNTVSVLRKFFSHDIICVEKLIIYFIDNKDLQGVYKTPLFVAAVCTDWIQNASAQDKFQDVTLFQSYMQYLSLKYKATAEPLQATVSSCGQLALTGLFSSCFEFNSDDLAEAGVDEDEKLTTLLMSKFTAQRLRPVYRFLGPLFQEFLAAVRLTELLSSDRQEDQDLGLYYLRQIDSPLKAINSFNIFLYYVSSHSSSKAAPTVVSHLLQLVDEKESLENMSENEDYMKLHPQTFLWFQFVRGLWLVSPESSSSFVSEHLLRLALIFAYESNTVAECSPFILQFLRGKTLALRVLNLQYFRDHPESLLLLRSLKVSINGNKMSSYVDYSFKTYFENLQPPAIDEEYTSAFEHISEWRRNFAQDEEIIKNYENIRPRALPDISEGYWKLSPKPCKIPKLEVQVNNTDAADQALLQVLMEVFSASQSIEFRLFNSSGFLESICPALELSKASVTKCSMSRLELSRAEQELLLTLPALQSLEVSETNQLPEQLFHNLHKFLGLKELCVRLDGKPNVLSVLPREFPNLLHMEKLSIQTSTESDLSKLVKFIQNFPNLHVFHLKCDFLSNCESLMAVLASCKKLREIEFSGRCFEAMTFVNILPNFVSLKILNLKDQQFPDKETSEKFAQALGSLRNLEELLVPTGDGIHQVAKLIVRQCLQLPCLRVLTFHDILDDDSVIEIARAATSGGFQKLENLDISMNHKITEEGYRNFFQALDNLPNLQELNICRNIPGRIQVQATTVKALGQCVSRLPSLIRLHMLSWLLDEEDMKVINDVKERHPQSKRLIIFWKLIVPFSPVILE
What is the function of this protein?
Sensor component of the NLRC4 inflammasome that specifically recognizes and binds flagellin from pathogenic bacteria such as Legionella or Salmonella (PubMed:12526741, PubMed:21874021, PubMed:21918512, PubMed:29146805, PubMed:29182158).  Association of pathogenic bacteria proteins drives in turn drive assembly and activation of the NLRC4 inflammasome, promoting caspase-1 activation, cytokine production and macrophage pyroptosis (PubMed:21874021, PubMed:21918512, PubMed:29146805, PubMed:29182158).  The NLRC4 inflammasome is activated as part of the innate immune response to a range of intracellular bacteria.  The NLRC4 inflammasome senses Gram-negative bacteria such as L. pneumophila and P. aeruginosa, enteric pathogens S. typhimurium (Salmonella) and S. flexneri (PubMed:21874021, PubMed:21918512, PubMed:29146805, PubMed:29182158).  May contribute to prevent motor-neuron apoptosis induced by a variety of signals (By similarity).
What are the official names of this protein?
Baculoviral IAP repeat-containing protein 1e, Neuronal apoptosis inhibitory protein 5.
Protein: SYE_ENDTX
Sequence: MSGIRVRFAPSPTGDLHIGGVRTALFNWLFAKNKGGKFILRIEDTDETRSTGESAKVILDAMKWLELEWNEGPGNENLKYSPYSQMKRKERGIYRKYADELVAKELAYPCYCTPEEIDVMRKKAKADKLPPKYDGKCRHLTPGQRKQKEIEGKKAVVRFKMFGSGTTVLNDIIRGRVKFDNSLLDDFVIMKASGVPAYNFACVVDDYLMEITHVLRGDDHISNAPRQMHIYNALGWEMPEFAHMSMILGAGGARLSKRHGHTSVLEYRKEGYLREALINYLALLGWSTEDSQQIFTIEELKQKFSVERCGISPSIFDPAKLLWLNGEKIRSKTPQQVYELFIDWLKYTGNEKLTETWDVELLKKALILEHDKIKLLKDIPSLVDFFFTKNVDYKEEAVKKTLLSEKSKDIAKLVLIESAARLPNQLDFSAISLEQYARNLAAEKNIKTGQVFHPIRVAISGRMQGPGLFQMMEVMGKEDVVRRINVAINKFFQK
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.