PharMolix/UniProtQA huggingface dataset:
Protein: LIPA_ECOL6
Sequence: MSKPIVMERGVKYRDADKMALIPVKNVATEREALLRKPEWMKIKLPADSTRIQGIKAAMRKNGLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPFCDVAHGRPVAPDANEPVKLAQTIADMALRYVVITSVDRDDLRDGGAQHFADCITAIREKSPQIKIETLVPDFRGRMDRALDILTATPPDVFNHNLENVPRIYRQVRPGADYNWSLKLLERFKEAHPEIPTKSGLMVGLGETNEEIIEVMRDLRRHGVTMLTLGQYLQPSRHHLPVQRYVSPDEFDEMKAEALAMGFTHAACGPFVRSSYHADLQAKGMEVK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SP3AE_BACSU
Sequence: MKRFQWVLLLAVLIIAGRAEIVQAAGNAEQTEDHAETAEQLAERTAASLETDKIGEFWNDIMTEYGGLLPESQKGSLMEFINGDKSFSPQEWLKALFSYLFHEVLANGKLLGTLILLTIFCVILQLLQNAFQQSTVSKVAYSIVYMVLIILALNSFHVAINYATEAIQTMTSFILALIPLLLALLASSGGAVSAAFFHPVILFLMNTSGLLIQNIVMPLIFLSAILSIVSTMTEQYKVTQLANLLRNIAIGALAVFLTIFLGVISVQGASAAVTDGITLRTAKFITGNFIPVLGRMFTDATDTVISASLLLKNTVGILGVAILICIAAFPAIKVLSLAFIYKLAAAILQPLGGGPVITCLDVISKSVIYIFAALAIVSLMFFLSLTVIITAGNLTMMMK
What is the function of this protein?
Required during sporulation for activation of sigma factor SpoIIIG/SigG after engulfment is completed in the prespore.  Overexpression in the absence of SpoIIIJ is synthetically lethal.
What are the official names of this protein?
Stage III sporulation protein AE.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Signal sequence cleavage facilitates function; replacing the signal with the first transmembrane region of SpoIVFB decreases sporulation 7-fold, whereas replacing it with the SleB signal sequence does not affect sporulation.
Protein: UREE_PARDP
Sequence: MIPCSDRIIRNAPGPFDAEVVLDYESRLLRRKRLACAGGDFMVDLAEVASLEDGDAFALSDGRIVVVRAAAEPVLVVRGPLARLAWHIGNRHTPCRIEADRLIIRQDHVLEAMLRRLGAEISHQNLPFRPEGGAYGHGRTFGHDHGHAHDHHHA
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YPSC_BACSU
Sequence: MKKYTLIATAPMGIEAVVAKEVRDLGYECKVDNGKVIFEGDALAICRANLWLRTADRIKVQVASFKAKTFDELFEKTKAINWRSFIPENGKFPVIGKSVKSTLASVPDCQRIVKKAIVEKLKLQSGKANDWIEETGAEYKVEISLLKDQALITLDSSGTGLHKRGYRVDQGGAPIKETLAAALVQLTNWTPDRPFVDPFCGSGTIAIEAALIGQNIAPGFNRDFVSEDWEWIGKDLWNKARLEVEEKANYDQPLTIFASDIDHRMVQIAKENAEEAGLGDLIQFKQMQVKDFTTNLEFGVIVGNPPYGERLGEKKAVEQMYKEMGQAFEPLDTWSVYMLTSNENFEEAYGRKATKKRKLFNGFIKTDYYQYWSKVRPQRKKTENA
What are the official names of this protein?
Putative RNA methyltransferase YpsC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: LGT_CUPNH
Sequence: MLIHPQFDPVAIHLGPLAIRWYGLMYLAGFIMFLGFGRLRIRQPHIAAKGWTTRDLDDMLFFGVLGVILGGRLGYVLFYKPSYYLAHPLEILKVWEGGMAFHGGFLGVVVAMWLFGKLRRRHWMEVTDFIAPMIPCGLAAGRIGNFINGELWGRATDLPWGMIFPQAGDNIPRHPSQLYQFAGEGVALFIVLWLFARKPRPMGAVSGVFLIGYGAFRFAAEFAREPDNFLGLLALKLSMGQWLSLPMILAGIAMVVWAYRRQPGAGASQPVA
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MGP4_ARATH
Sequence: MAQQKFLHQRPIQNPFTNPFSSSPLSTSSISNRPISLLSRNGLLLLLALLVILGVFLPWAGSPLFPSPNKLSPSQSKWRDYSLPQAVKFVAKNGTVIVCAVSYPYLPFLNNWLISVSRQKHQDQVLVIAEDYATLYKVNEKWPGHAVLIPPALDSQTAHKFGSQGFFNFTARRPQHLLEILELGYNVMYNDVDMVWLQDPFQYLEGKHDAYFMDDMTAIKPLDHSHDLPPPGKKGRTYICSCMIFLRPTNGAKLLMKKWIEELETQPWSRAKKANDQPGFNWALNKTANQVDMYLLSQAAFPTGGLYFKNKTWVKETKGKHAIIHNNYIVGFEKKIKRFRDFNLWLVDDHASESPLGKLE
What is the function of this protein?
Catalyzes the transfer of D-xylose from UDP-alpha-D-xylose onto L-fucose.  Probably involved in the biosynthesis of rhamnogalacturonan II (RG-II) through xylosylation of the internal fucose moiety of the A-chain of RG-II, a structurally complex pectic polysaccharide of the primary cell wall.  RG-II is essential for the cell wall integrity of rapidly growing tissues such as roots and pollen tube growth and elongation.
What are the official names of this protein?
UDP-D-xylose:L-fucose alpha-1,3-D-xylosyltransferase MGP4, Protein MALE GAMETOPHYTE DEFECTIVE 4, Rhamnogalacturonan xylosyltransferase MGP4.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 77 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: URE2_PARP8
Sequence: MIPGELITDDGELELNAGRATVTVTVSNTGDRPVQVGSHYHFYEVNAALSFDREAARGFRLNIAAGTAVRFEPGQERTVELVALAGDRVVYGFNGKVMGKL
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: US03_HCMVM
Sequence: MKPVLVLAILAVLFLRLADSVPRPLNVVVSEIKSAHFRVEENQCWFHMGMLYFKGRMSGNFTKKHFVNVGIVSQSYMDRLQVSGEQYHHDERGAYFEWNIGGYPVSHTVDMVDITLSTRWGDPKKYAACVPQVRMDYSSQTINWYLQRSMRDDNWGLLFRTLLVYLFSLVVLVLLTVGVSARLRFI
What is the function of this protein?
Retains, but does not degrade MHC class I heterodimers in the endoplasmic reticulum during the immediate-early period of virus infection, thereby impairing their transport and maturation.  Forms a complex with beta-2-microglobulin-associated class I heavy chains, which accumulate in the ER.  In consequence, infected cells are masked for immune recognition by cytotoxic T-lymphocytes.
What are the official names of this protein?
Membrane glycoprotein US3.
What is the protein family that this protein belongs to?
Belongs to the cytomegalovirus US2 family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: INSC_MOUSE
Sequence: MRRPPGDGDSTGEGPGNWGLWGAQESRRLCCVGPDRCGQALLQIGINMMALPGGRHLDSVPLQEQRLHFMQVDSVQRWMEDLKLMTECECMCVLQAKPISLEEDTQGDLILAGGPGPGDPLQLLLKRGWVISTELRRIGQKLAQDRWARVHSMSVRLTCHARSMVSEYSTISRTASQEMGQAEKLLMEKCSELSAVTERCLQVENEHVLKSMKACVSETLSLLGEHFGQLLELALTREVQALVRKIDTSDNIYITESTTGNLFGLTQEGAPLCRIIAKEGGVVALFKVCRQDSFRCLYPQALRTLASICCVEEGVHQLEKVDGILCLADILTDESHSEATRAEAAAVVAQVTSPHLSFTQHLTSFLENMEEIVTALIKLCQEASSGEVFLLASAALANITFFDKMACEMLLQLNAIRVLLEACGDKQRVDTPYTRDQIVTILANMSVLEQCGSDIIQENGVQLIMGMLSEKPRSGTPAEVAACERVQQKAAVTLARLCRDPDVAQEAVRLSCMSRLIELCRSPSERNSSDAVLVACLAALRRLAGVCPEGLQDSDFQQLVQPRLVDSFLLCSNMEESFV
What is the function of this protein?
May function as an adapter linking the Par3 complex to the GPSM1/GPSM2 complex.  Involved in spindle orientation during mitosis (PubMed:16301171, PubMed:21816348).  May regulate cell proliferation and differentiation in the developing nervous system (PubMed:16301171).  May play a role in the asymmetric division of fibroblasts and participate in the process of stratification of the squamous epithelium (PubMed:16094321).
What are the official names of this protein?
Protein inscuteable homolog, Minsc.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cell cortex. Note=Uniformly distributed in the cytoplasm during interphase. During metaphase, detected in the cell cortex, adjacent to the mitotic spindle poles.
Protein: RS14_HALHL
Sequence: MAKNSMVERDRKRRKLAQKYSAKRERLKAIIESPESSVEERFEAQLKLQQIPRNASPVRQRNRCAKSGRPRGYYRKFGLARNELRRAAMNGEIPGLTLSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: PSBN_OENEH
Sequence: METATLVAISISGLLVSFTGYALYTAFGQPSQQLRDPFEEHGD
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: ATPB_STRPI
Sequence: MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIVLEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDLEAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVGKTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEPPGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQLGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDEEKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAFRGVGSIEDVIAKAEKMGF
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CR15B_ARATH
Sequence: MAMSLSGAVLSGMGSSFHNVGAKQSGVGTVRVGRKSELVVVAQRKKSLIYAVKSDGNILDDLNEATKKASDFVTDKTKEALADGEKTKDYIVEKTIEANETATEEAKKALDYVTEKGKEAGNKAAEFVEGKAEEAKNATKS
What is the function of this protein?
Exhibits cryoprotective activity toward stromal substrates in chloroplasts and in protoplasts and confers freezing tolerance to plants in a CBF-dependent manner.  Protectant against various stresses (e. g.  cold, drought and heat stress) by preventing protein aggregation and attenuating enzyme inactivation.  Influences the intrinsic curvature of the inner membrane of the chloroplast envelope, and modulates the freeze-induced lamellar-to-hexagonal II phase transitions that occur in regions where the plasma membrane is brought into close apposition with the chloroplast envelope during freeze-induced osmotic contraction (By similarity).  Mediates a shift in the melting curves of phospholipids-containing membranes to lower temperatures (PubMed:20510170).  Involved in the regulation of leaf senescence by abscisic acid (ABA) in a VNI2-dependent manner (PubMed:21673078).
What are the official names of this protein?
Protein COLD-REGULATED 15B, chloroplastic, AtCOR15B.
What is the protein family that this protein belongs to?
Belongs to the COR15 protein family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: FABA_BLOFL
Sequence: MFNKQEFYTKEDLLNSSKGNLFGKKGPVLPAPNMLMIDRITKMTTNGGNYNKGFVSAELDIRSDMWFFSCHFINDPVMPGCLGLDAMWQLVGFYLGWIGGKGRGRALGVKEVKFTGQILPTAKTVTYLIHFRKIITRTLIMGMADGEVMCDNKIIYTAADLKVGLFTNISTF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3746_HAHCH
Sequence: MNISKPEQRTLHVLAKGGRIIFTRNSSGKVTFVECYTREGYVLADCTLPVFTKLKNKRLIHSKSGKPYQINMAGLKAVRPQLDNQ
What are the official names of this protein?
UPF0386 protein HCH_03746.
What is the protein family that this protein belongs to?
Belongs to the UPF0386 family.
Protein: SYK_STAA3
Sequence: MSEEMNDQMLVRRQKLQELYDLGIDPFGSKFDRSGLSSDLKEEWDQYSKEELVEKEADSHVAIAGRLMTKRGKGKAGFAHVQDLAGQIQIYVRKDQVGDDEFDLWKNADLGDIVGVEGVMFKTNTGELSVKAKKFTLLTKSLRPLPDKFHGLQDIEQRYRQRYLDLITNEDSTRTFINRSKIIQEMRNYLNNKGFLEVETPMMHQIAGGAAARPFVTHHNALDATLYMRIAIELHLKRLIVGGLEKVYEIGRVFRNEGVSTRHNPEFTMIELYEAYADYHDIMDLTESMVRHIANEVLGSAKVQYNGETIDLESAWTRLHIVDAVKEATGVDFYEVKSDEEAKALAKEHGIEIKDTMKYGHILNEFFEQKVEETLIQPTFIYGHPTEISPLAKKNPEDPRFTDRFELFIVGREHANAFTELNDPIDQKGRFEAQLVEKAQGNDEAHEMDEDYIEALEYGMPPTGGLGIGIDRLVMLLTDSPSIRDVLLFPYMRQK
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTU1_YEAS1
Sequence: MSFTAPSDPVNKPTKVKVSQLCELCHSRKALIRRPKNLSKLCKQCFCLVFETEIHNTIVANNLFQRGEKVAVGASGGKDSTVLAHMLKLLNDRYDYGIEIVLLSIDEGIIGYRDDSLATVKRNQQQYGLPLEIFSFKDLYDWTMDEIVSVAGIRNSCTYCGVFRRQSLDRGAAKLGISHVVTGHNADDMAETVLMNILRGDVARLEKSTAIITQSSGSPIKRSKPFKYSYQKEIVLYAHYMKLDYFSTECTYAPEAFRGTAREYMKNLEAVRPSCIIDIIQSGENLALKAKKSNARKRVVKFVDGNRCARCGYLSSNNICKACMLLEGLEKSRAQVAIENDTSADGAALKLRALEKLSF
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation.  It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.  Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation.  May also be involved in protein urmylation.
What are the official names of this protein?
Cytoplasmic tRNA 2-thiolation protein 1, Cytoplasmic tRNA adenylyltransferase 1, Needs CLA4 to survive protein 6, Thiolation of uridine in cytoplasmic tRNA protein 1.
What is the protein family that this protein belongs to?
Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion.
Protein: GLGB_MYCSK
Sequence: MAKTKGLPKDTAVTPSPHLRPHTADLNRLLAGEHHDPHSILGAHEYDDHTVIRAYRPHATEVAAVVGGERHVFTHLEAGVFAVTLPFTGLIDYRLEVGYDHGGDQPHIHHTADAYRFLPTLGEMDLHLFSEGRHERLWEVLGAHPRTFETPDGVVEGVSFAVWAPNANGVQLIGDFNHWDGNEAQLRVLGSTGVWELFWPDFPVDGLYKFRIHGADGVVSERADPMAFATEVPPQTASRVTTSSYTWNDDAWMTQRAAQNPVFEPMSTLEVHLMSWRPGLSYVELADQLTEYIVEHGFTHVEMLPVAEHPFGGSWGYQVTSYYAPTSRLGTPDEFRYLVDRLHQAGIGVIVDWVPAHFPKDAWALGRFDGTALYEHADPRRGEQLDWGTYVFDFGRAEVRNFLVANALYWLQEFHVDGLRVDAVASMLYLDYSRPEGGWTPNIYGGRENLEAVQFLQEMNATVHKASPGIVTIAEESTSWPGVTRPTNLGGLGFSMKWNMGWMNDTLAFISRDPIHRSYHHHEMTFSMLYAFSENYVLPISHDEVVHGKGTLWGRMLGDDHRKAAGVRQLLAYQWAHPGKQLLFQGQEFGQRAEWSEERGVDWYQLDENSYSGGILRMISDMNGIYTSHRALWSHDTSPEGYSWIDANDSTNNVLSFLRYGDDGSVLACVFNFSGSEHSQYRLGLPHAGTWREVLNTDAADYNGAGIGNYGAVQATDEPWHGRPASAVMVLPPLSALWFEPVAAEAPVVQEPPTAPPLS
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: SYL_PSET1
Sequence: MQEQYNPQKIESKIQRYWEENKVFKVTEDESKEKYYCLSMFPYPSGRLHMGHVRNYTIGDVVSRFQRLKGKNVMQPMGWDAFGLPAENAAIKNKTAPAKWTYENIDYMRTQLKQLGFGYDWDREIATCHPEYYKWEQWFFTKLYEKGLVYKKMSTVNWDPVDQTVLANEQVIDGRGWRSGAVVEQKEIPQWFIKITDYAQELLDDLDKLEDWPEQVKTMQRNWIGRSEGCDIEFKRTDNNETFSVYTTRPDTFMGVTYVAVAAGHPIAKEAAKNSDSVALFVEECKNNKVSEADMATMEKKGIATGFFATHPLTGEQVPIWIANFVLMHYGSGAVMAVPAHDQRDFEFATAYGLDIKQVIAPVTGSDLEVNLNKEAFTDKGVLVNSGEFDGLDFDAAFNAIADKLEALGVGERKVNFRLRDWGVSRQRYWGSPIPMLSDEDGNELAATDDMLPVRLPEDVVMNGVTSPIKADPNWAKTTMNGAPAFHETDTFDTFMESSWYYARYCSPRHDEGMLDPAAANYWLPVNQYIGGIEHAILHLLYSRFFHKLLRDFGLVDSDEPFDRLLCQGMVLAETFYRKDEKGADIWISPSDVNTETDDKGRVTKAWHKVDGNPVFSSGMSKMSKSKNNGIDPQHVIAQYGADTVRLFMMFTAPPEQTLEWSDAGVEGAHRFLKRVWKYAVDVKTVGFQPLNKTALNNEQKVLRRDLHKAIAKVSDDVERRQTFNTAIAAIMELSNKLLKAPLNSKQDVAIANEALEAMLIMLAPITPHLSHQLWQELGKEGDIVNASWPEVDQSALVEDEKLIIIQVNGKLRAKLTVAADATKEQVEALAFEQASVTKYTDGVTVRKVIYVPGKLLNVVAN
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPF_MYCPA
Sequence: MNTTPRIGLGVDVHPIQPGRPCRLLGLLFDDADGCAGHSDGDVGAHALCDAVLSAAGLGDVGAVFGVDDPRWAGVSGADMLRHVADLTARHGFRVGNAAVQVIGNRPKVGPRRAEAQRVLSELLGAPVSVAATTTDGLGLTGRGEGLAAIATALVVPTG
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: CAD_ASPTN
Sequence: MTKQSADSNAKSGVTAEICHWASNLATDDIPSDVLERAKYLILDGIACAWVGARVPWSEKYVQATMSFEPPGACRVIGYGQKLGPVAAAMTNSAFIQATELDDYHSEAPLHSASIVLPAVFAASEVLAEQGKTISGIDVILAAIVGFESGPRIGKAIYGSDLLNNGWHCGAVYGAPAGALATGKLLGLTPDSMEDALGIACTQACGLMSAQYGGMVKRVQHGFAARNGLLGGLLAYGGYEAMKGVLERSYGGFLKMFTKGNGREPPYKEEEVVAGLGSFWHTFTIRIKLYACCGLVHGPVEAIEKLQRRYPELLNRANLSNIRHVYVQLSTASNSHCGWIPEERPISSIAGQMSVAYILAVQLVDQQCLLAQFSEFDDNLERPEVWDLARKVTPSHSEEFDQDGNCLSAGRVRIEFNDGSSVTETVEKPLGVKEPMPNERILHKYRTLAGSVTDESRVKEIEDLVLSLDRLTDITPLLELLNCPVKSPLV
What is the function of this protein?
Involved in the production of itaconic acid, a soluble unsaturated dicarboxylic acid mainly produced from sugars.
What are the official names of this protein?
Cis-aconitate decarboxylase, CAD, aCAD, Aconitate decarboxylase, Cis-aconitic acid decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PrpD family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MATP_SALTI
Sequence: MKYQQLENLESGWKWKYLVKKHREGELITRYVEASAAQEAVNLLLALENEPVRVNVWIDRHMNPALLNRMRQTIRARRKRHFNAEHQHTRKKSIDLEFMVWQRLAGLAQRRGKTLSETIVQLIEDAEHKEKYATQMTTLKQDLQALLGKK
What is the function of this protein?
Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle.  Prevents early segregation of duplicated Ter macrodomains during cell division.  Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.
What are the official names of this protein?
Macrodomain Ter protein.
What is the protein family that this protein belongs to?
Belongs to the MatP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MGSA_SALPA
Sequence: MELTTRTLPTRKHIALVAHDHCKQMLMNWVERHQPLLEKHVLYATGTTGNLIQRATGMDVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVSTADFIIQSPHFNDAVDILIPDYARYLAERLK
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: NA24_HETCR
Sequence: GNCKCDDEGPNVRTAPLTGYVDLGYCNEGWDKCASYYSPIAECCRKKK
What is the function of this protein?
Binds to site 3 of voltage-gated sodium channels and inhibits the inactivation process.
What are the official names of this protein?
Delta-stichotoxin-Hcr1c, Delta-SHTX-Hcr1c, Neurotoxins IV, RTX-IV, Rm4.
What is the protein family that this protein belongs to?
Belongs to the sea anemone sodium channel inhibitory toxin family. Type II subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: TRI1_FUSSP
Sequence: MSKVDKTGYAQWVYLLPERSSMMSFIDSMEDFRFDMLIYFLCFVVLGRAVQWFLRPKPNAPLLNPRRFFEFSDSRAVSEILYSTRQVLEDWFSKYPTKPMRIIADLGQITILPPSMADEIKNDPRLSFIKASTESAFHITIPGFEPFREGAKNEAGLIKNVLHKHLNKTLNHITTPLAEETCLAVQEYFGSDQGWHKVPLRDTLVPLVTRISTRIFLGQDLCRNQEWLRIAASYSSTSAEVANHLRRWPKPLRYLVSLLSPECQNLAKQVRNARALINPILERRRVEEGQEKGTSYNDSLEWFERYAREAYDPAATQLFLSVVSIHTTTDLLCQALEDISSHPEIIKPLQHEIREVLKQEGWNTKALYKMKLLDSVLKESQRLKPVQHATMLRLALEDITLEDGTFIPKGHQISVSCHAMRDNEIYENASSWDGYRYYRQREQSANEHKAQLSSTSPEHMGFGYGIHVCPGRFFAANEVKVIMIYLLLQYEWRTPPGSQPKPLSWCTTWATDPTFELEVRRKGSDDIPVELSHNTFSRESES
What is the function of this protein?
Cytochrome P450 monooxygenase; part of 2-gene cluster involved in trichothecene C-8 modification that mediates the biosynthesis of T2-toxin (PubMed:14690377, PubMed:12620849).  The biosynthesis of trichothecenes begins with the cyclization of farnesyl diphosphate to trichodiene and is catalyzed by the trichodiene synthase TRI5 (PubMed:3800398).  Trichodiene undergoes a series of oxygenations catalyzed by the cytochrome P450 monooxygenase TRI4 (PubMed:7651333).  TRI4 controls the addition of four oxygens at C-2, C-3, C-11, and the C-12, C-13-epoxide to form the intermediate isotrichotriol (PubMed:16917519).  Isotrichotriol then undergoes a non-enzymatic isomerization and cyclization to form isotrichodermol (PubMed:2317042).  During this process, the oxygen at the C-2 position becomes the pyran ring oxygen and the hydroxyl group at C-11 is lost (PubMed:2317042).  More complex type A trichothecenes are built by modifying isotrichodermol through a series of paired hydroxylation and acetylation or acylation steps (PubMed:11352533).  Isotrichodermol is converted to isotrichodermin by the acetyltransferase TRI101 (PubMed:10583973).  TRI101 encodes a C-3 transacetylase that acts as a self-protection or resistance factor during biosynthesis and that the presence of a free C-3 hydroxyl group is a key component of Fusarium trichothecene phytotoxicity (PubMed:10583973).  A second hydroxyl group is added to C-15 by the trichothecene C-15 hydroxylase TRI11, producing 15-decalonectrin, which is then acetylated by TRI3, producing calonectrin (PubMed:9435078, PubMed:8593041).  A third hydroxyl group is added at C-4 by the cytochrome P450 monooxygenase TRI13, converting calonectrin to 3,15-diacetoxyspirpenol, which is subsequently acetylated by the acetyltransferase TRI7 (PubMed:12135578, PubMed:11352533).  A fourth hydroxyl group is added to C-8 by the cytochrome P450 monooxygenase TRI1, followed by the addition of an isovaleryl moiety by TRI16 (PubMed:12620849, PubMed:14532047).  Finally, the acetyl group is removed from the C-3 position by the trichothecene C-3 esterase TRI8 to produce T-2 toxin (PubMed:12039755).
What are the official names of this protein?
Cytochrome P450 monooxygenase TRI1, Trichothecene biosynthesis protein 1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.