PharMolix/UniProtQA huggingface dataset:
Protein: LMNA_MOUSE
Sequence: METPSQRRATRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLLAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTLKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQSQGGGSVTKKRKLESSESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIRRQNGDDPLMTYRFPPKFTLKAGQVVTIWASGAGATHSPPTDLVWKAQNTWGCGSSLRTALINSTGEEVAMRKLVRSLTMVEDNEDDDEDGEELLHHHRGSHCSGSGDPAEYNLRSRTVLCGTCGQPADKAAGGAGAQVGGSISSGSSASSVTVTRSFRSVGGSGGGSFGDNLVTRSYLLGNSSPRSQSSQNCSIM
What is the function of this protein?
Isoform C2 may have a role in determining the organization of nuclear and chromosomal structures during spermatogenesis.
What are the official names of this protein?
Prelamin-A/C.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Nucleus. Nucleus envelope. Nucleus lamina. Nucleus, nucleoplasm. Nucleus matrix. Note=Farnesylation of prelamin-A/C facilitates nuclear envelope targeting and subsequent cleavage by ZMPSTE24/FACE1 to remove the farnesyl group produces mature lamin-A/C, which can then be inserted into the nuclear lamina. EMD is required for proper localization of non-farnesylated prelamin-A/C (By similarity).
Protein: RL13_TETTS
Sequence: MKHNNQLPVAQLRKHQQFRIKTFFNQAAQKKARLHARRAQAAAVFPRPTEKLQPVVRKQTQRYNKSTKLGRGFTLQELKAAGISAAFAQSIGIKVDHRRKNRCQESLELNKKRLLAYVSKLVLFPRHQGKAKKGLVNDTADTSSAAQNALQTSVPLPSVSKREKAVSNIAELRKKKVYRIIRQEKTNQKWDGKRKAKAQAAAEPKA
What are the official names of this protein?
60S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL13 family.
Protein: ETFA_CLOPA
Sequence: MNIADYKGGVWVFAEQXDG
What is the function of this protein?
The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases.  It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity).
What are the official names of this protein?
Electron transfer flavoprotein subunit alpha, Alpha-ETF, CP 14, Electron transfer flavoprotein large subunit, ETFLS.
What is the protein family that this protein belongs to?
Belongs to the ETF alpha-subunit/FixB family.
Protein: RS12_ACISJ
Sequence: MPTINQLVRQGRTVEVVKSKSPAMENCPQRRGVCTRVYTTTPKKPNSALRKVAKVRLTNGFEVISYIGGEGHNLQEHSVVLVRGGRVKDLPGVRYHIVRGSLDLQGVKDRKQARSKYGAKKPKAK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: TRPG_MYCTO
Sequence: MRILVVDNYDSFVFNLVQYLGQLGIEAEVWRNDDHRLSDEAAVAGQFDGVLLSPGPGTPERAGASVSIVHACAAAHTPLLGVCLGHQAIGVAFGATVDRAPELLHGKTSSVFHTNVGVLQGLPDPFTATRYHSLTILPKSLPAVLRVTARTSSGVIMAVQHTGLPIHGVQFHPESILTEGGHRILANWLTCCGWTQDDTLVRRLENEVLTAISPHFPTSTASAGEATGRTSA
What is the function of this protein?
Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan.  In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate.  In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia (By similarity).
What are the official names of this protein?
Anthranilate synthase component 2, AS, ASII, Anthranilate synthase, GATase component, Anthranilate synthase, glutamine amidotransferase component.
Protein: RL20_PHOPR
Sequence: MPRVKRGVQARARHKKVLKQAKGYYGARSRVYRVAFQAVTKAGQYAYRDRRQKKRTFRALWIARINAAARQNGLSYSRLINGLKKASIEIDRKILADIAVFDKATFTVLVEKAKAAL
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: ARNA_YERPN
Sequence: MKAIVFAYHDIGCVGLNALAEAGYDIQAVFTHTDNPGENRFFSSVARVAADLALPVFAPEDVNHPLWVERIRELQPDIIFSFYYRNMLSDEILSLAPQGGFNLHGSLLPQYRGRAPINWVLVNGETETGVTLHQMVKKADAGPIAGQYKVAISDVDTALTLHAKMRDAAQELLRNLLPRMKEGPLPLTPQKEADASYFGRRTAADGEIHWQKSAFTINNLVRAVTEPYPGAFSYLGQRKLTIWRSRPLDLVHNKLPGTVLSTAPLTVACGEGALEIITGQGEAGLYVQGDRLAQEMGIVTDVRLGNKPSNTLKRRTRVLILGVNGFIGNHLTERLLQDDRYEVYGLDIGSDAISRFLGNPAFHFVEGDISIHSEWIEYHIKKCDVILPLVAIATPIEYTRNPLRVFELDFEENLKIVRDCVKYNKRIVFPSTSEVYGMCDDKEFDEDTSRLIVGPINKQRWIYSVSKQLLDRVIWAYGVKEGLKFTLFRPFNWMGPRLDNLDAARIGSSRAITQLILNLVEGSPIKLVDGGAQKRCFTDIHDGIEALFRIIENRDGCCDGRIINIGNPTNEASIRELAEMLLTSFENHELRDHFPPFAGFKDIESSAYYGKGYQDVEYRTPSIKNARRILHWQPEIAMQQTVTETLDFFLRAAVIEKTAAPKDELNA
What is the function of this protein?
Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Bifunctional polymyxin resistance protein ArnA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
Protein: ERB1_MAGO7
Sequence: MAPTAPAKKRKQSAEVTELSDDEIIDGLLDGALSQSEDDSDFVASGDEDEEDEDEDEDEDKDEDDEHDDKQDIGDLQDLSLNDLDDDAQSKELAKDGANGGSGDGPEADDEDRPNYRVVEDANGGIRYVYDEINPVYDSDDSDKEEDNRIGDIPLSFYEAYPHVGYTIDGKKLMRPSERRQALDSLLDSIEIPKGWTGLTDPTTGKPLNLSQDELELLKRVQMNEIPEEGYDPYPDTVEYFTGIEEKMPLSAAPEPKRRFIPSKHEAKRVMKLVRAIREGRIQPYKSKEEREKEEEGKEEKYYDVWQDEQPRDPHVMHIPAPKLAPPGYDMSYNPPPEYLPTKAEREEWEKMDPEDREKEYLPQKFDALRKVPGYETFVKERFERCLDLYLAPRVRKNRLNIDPASLLPKLPRPEELKPFPTVCQAIFRGHEGRVRSSAIDPTGLWLATGGDDGYVRIWLINPARQVWAVKLSSDEAVNAVRWRPTKDTMILAAAAGEEIFLMVPPDIDPEVEQTSRAVLDAGFGHAAGGADKQTTDGKAPAAKWARPGARLEDEGVLVKVTVRSPVKVISWHRRGDHFCTVSPSGQRSSVAVHTLSKHLSQIPFRKLSGLAQVAHFHPSRPLFFVATQRTIRCYDLQRLELVKVVQPGARWISSFDIHPGGDNLIVGSYDRRLLWHDLDLSTRPYKTMRFHPQAIRAVKYHRGGLPLFADASDDGSLQIFHGKVVSDLMENATIVPLKSLKGHRVVDSLGVMDVDWHPSEPWCISAGADGTCRLWM
What is the function of this protein?
Component of the NOP7 complex, which is required for maturation of the 25S and 5. 8S ribosomal RNAs and formation of the 60S ribosome.
What are the official names of this protein?
Ribosome biogenesis protein ERB1, Eukaryotic ribosome biogenesis protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat BOP1/ERB1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: LAMB2_YERPN
Sequence: MKTSLRTLSVALAAALVSPSVLAIEKIDFHGYMRAGVGVSSDGGLAEWQKTMVGRLGNESDTYGEIGLGAEVYKKEDVSFYLDSMVSMLSDGSNDSETTIGDDAQFGLRQLNLQIKGLIPGDKEAVIWGGKRYYQRHDLHIIDTKYWNISGSGAGIENYTVGPGAVSVAWVRGDANDVDTRITGDSDVNINYIDVRYAGFKPWAGSWTEVGIDYAMPNPTKQQKEYGGLYDADNAVMLTGEISQDMFGGYNKLVLQYANKGLAQNMISQGGGWYDMWHKTDEAKGYRVINTGLIPITDKFSFNHVLTWGSANDITEYTDKTNLISLVGRAQYQFTQYVRAIGEVGGFYQKDTYHNGSNYKQGGEKYTIALGLAEGPDFLSRPELRVFASYLNDSENGKPFEDGTSNDTWNFGVQVEAWW
What is the function of this protein?
Involved in the transport of maltose and maltodextrins.
What are the official names of this protein?
Maltoporin 2, Maltose-inducible porin 2.
What is the protein family that this protein belongs to?
Belongs to the porin LamB (TC 1.B.3) family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: SNU13_DEBHA
Sequence: MSAPNPKAFPLADSALTQQILDVVQQSQNLRQLKKGANEATKTLNRGISEFIIMAADTEPIEILLHLPLLCEDKNVPYVFVPSKTALGRACGVSRPVIAASVTTNEASAMKNQIYGIKDKIETLLI
What is the function of this protein?
Common component of the spliceosome and rRNA processing machinery.  In association with the spliceosomal U4/U6. U5 tri-snRNP particle, required for splicing of pre-mRNA.  In association with box C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and site-specific 2'-O-methylation of substrate RNAs.  Essential for the accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs (By similarity).
What are the official names of this protein?
13 kDa ribonucleoprotein-associated protein.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: MDM12_LODEL
Sequence: MSFDINWEKLTTDNQINDSIKNFLHEQFQSLQLPSYISNLEVVDFKLGTIPPEITIRHIGDPFEEFYANPDDGDGDGNNDEEVLKDKSTKLKNRQAVNIIPNKAGATHEADIINDHDYGDEDDIDDDYDNDSDDYDDDENDGLHDHGEDEENEESSQYDEDRLSNITEGLSLVELLASASTPKRTSPQRPPLISPRGEVTQQTLSKPKEPFQSILNPYGVTSVLNQGSNAAKNTTATSIAAGTTAANGVGTLKDIFDQNNFSSRVIPKIKTKEESVSGDQQQGKQTGKANEKGQKHKHEHEEEQGSDKQNAKNKASDDVQLILEINYKGNLYIDLLVTLLVNYPSPNFISLPIKLHVTDLVIHTIATIAYLKHAVYVSFLCDVNDEADGFSGASSNASTPNVTGTTSGGGNSGGNIVDYYFSDPNNKERIDIIKKIKIESEIGEVENNILRNVGKVEKFLMEQLRAILRDEIAWPSWICVDMAENDDEEEDDDDDDHDEDNEGRGRMRDTGDVDVRDHDKKED
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.  The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 12, Mitochondrial inheritance component MDM12.
What is the protein family that this protein belongs to?
Belongs to the MDM12 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: PRT14_ONCMY
Sequence: MPRRRRSSRPPVRRRRRPRVSRRRRRRGGRRRR
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Protamine TP14.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: Y559_MYCTO
Sequence: MKGTKLAVVVGMTVAAVSLAAPAQADDYDAPFNNTIHRFGIYGPQDYNAWLAKISCERLSRGVDGDAYKSATFLQRNLPRGTTQGQAFQFLGAAIDHYCPEHVGVLQRAGTR
What are the official names of this protein?
Uncharacterized protein MT0585.
Protein: OMPA_NEIGO
Sequence: MKKSLIALTLAALPVAAMADVTLYGTIKAGVETSRSVAHHGAQADRVKTATEIADLGSKIGFKGQEDLGNGLKAIWQLEQKAYVSGTDTGWGNRQSFIGLKGGFGKVRVGRLNSVLKDTGGFNPWEGKSYYLGLSNIAQPEERHVSVRYDSPEFAGFRAVQYVPNDNSGKNHSESYHAGFNYKNSGFFVQYAGFYKRHSYTTEKHQVHRLVGGYDHDALYASVAVQQQDAKLTWRNDNSHNSQTEVAATAAYRFGNVTPRVSYAHGFKGSVYDADNDNTYDQVVVGAEYDFSKRTSALVSAGWLQRGKGTEKFVATVGGVGLRHKF
What is the function of this protein?
Serves as a slightly cation selective porin.  Major antigen on the gonococcal cell surface and it may have pathogenic properties in addition to its porin activity.
What are the official names of this protein?
Major outer membrane protein P.IA, PIA, Protein IA, Class 1 protein.
What is the protein family that this protein belongs to?
Belongs to the Gram-negative porin family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: PIRL9_ARATH
Sequence: MAAEPNPKNFPVLSYVLARLPSFTAKSPSSSVPPFDIEQPPPSSSSSSIEIVTQMPHLTQPDVLASMTSAISDVAETRSILRTLGPRPDHESVDKARAKLSEIESFLSESFEDIALTDAAAKDEKRRQEMDQEKTWCESILKLDEVHASYEKLLKEAEERLVRIYESAEKNAAEDEENVAAVEVNEEVVGILQHASANPVDRVDLSGRKLRLLPEAFGRIQGLLVLNLSNNKLESIPDSIAGLHSLVELDVSTNSLETLPDSIGLLSKLKILNVSTNKLTSLPDSICRCGSLVILDVSFNRLTYLPTNIGPELVNLEKLLVQYNKIRSFPTSIGEMRSLKHLDAHFNELNGLPDSFVLLTNLEYLNLSSNFSDLKDLPFSFGELISLQELDLSNNQIHALPDTFGTLDSLTKLNVDQNPLVVPPEEVVKEGVEAVKTYMGQRRISMLEEEEKKKMEEEMEQANAGWLTRTTSKLKTYVADVSEYLGSNSPRDPYLERQL
What is the function of this protein?
Leucine-rich repeat protein that likely mediates protein interactions, possibly in the context of signal transduction.  PIRL9 acts redundantly with PIRL1 in the differentiation of microspores into pollen.
What are the official names of this protein?
Plant intracellular Ras-group-related LRR protein 9.
What is the protein family that this protein belongs to?
Belongs to the SHOC2 family.
Protein: RPOA_TRICV
Sequence: MNNFYIKCLKSKKVESGSIYGQFVIKSLHPGQGITIGNLFRRVLLSDLGGTAITGVRIAGVRDEFSTIPGIREDILEILLNLKGIVLKSKTNDLKFGRLKIKGPAVVTANCIQLPSEVEIVNPNHYIATITTSNVLEIEFKIESGTGYKLAGQTFCKKSQDYLQIDAIFMPVQKVDFKIENIYDNSNDLTERLFLDIWTNGSMSPEEAVSSASRFIISFFSSLLENKLPQETKESENKTLSAPKNPHTNIAIEELHLSVRAYNCLKRAQINTIGDLLKYSPEKLQELKNFGRKSADEVFTTLKNKLGIVLSN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: S31A3_HUMAN
Sequence: MENLPFPLKLLSASSLNAPSSTPWVLDIFLTLVFALGFFFLLLPYLSYFRCDDPPSPSPGKRKCPVGRRRRPRGRMKNHSLRAGRECRRGLEETSDLLSQLQSLLGPHLDKGDFGQLSGPDPPGEVGERAPDGASQSSHEPMEDAAPILSLLASPDPQAKHPQDLASTPSPGPMTTSVSSLSASQPPEPSLPLEHPSPEPPALFPHPPHTPDPLACSLPPPKGFTAPPLRDSTLITPSHCDSVALPLGTVPQSLSPHEDLVASVPAISGLGGSNSHVSASSRWQETARTSCAFNSSVQQDHLSRHPPETCQMEAGSLFLLSSDGQNVVGIQVTETAKVNIWEEKENVGSFTNRMTPEKHLNSLRNLAKSLDAEQDTTNPKPFWNMGENSKQLPGPQKLSDPRLWQESFWKNYSQLFWGLPSLHSESLVANAWVTDRSYTLQSPPFLFNEMSNVCPIQRETTMSPLLFQAQPLSHLGPECQPFISSTPQFRPTPMAQAEAQAHLQSSFPVLSPAFPSLIQNTGVACPASQNKVQALSLPETQHPEWPLLRRQLEGRLALPSRVQKSQDVFSVSTPNLPQESLTSILPENFPVSPELRRQLEQHIKKWIIQHWGNLGRIQESLDLMQLQDESPGTSQAKGKPSPWQSSMSTGESSKEAQKVKFQLERDPCPHLGQILGETPQNLSRDMKSFPRKVLGVTSEELERNLRKPLRSDSGSDLLRCTERTHIENILKAHMGRNLGQTNEGLIPVRVRRSWLAVNQALPVSNTHVKTSNLAAPKSGKACVNTAQVLSFLEPCTQQGLGAHIVRFWAKHRWGLPLRVLKPIQCFKLEKVSSLSLTQLAGPSSATCESGAGSEVEVDMFLRKPPMASLRKQVLTKASDHMPESLLASSPAWKQFQRAPRGIPSWNDHEPLKPPPAGQEGRWPSKPLTYSLTGSTQQSRSLGAQSSKAGETREAVPQCRVPLETCMLANLQATSEDVHGFEAPGTSKSSLHPRVSVSQDPRKLCLMEEVVSEFEPGMATKSETQPQVCAAVVLLPDGQASVVPHASENLVSQVPQGHLQSMPTGNMRASQELHDLMAARRSKLVHEEPRKPNCQGSCKSQRPMFPPIHKSEKFRKPNLEKHEERLEGLRTPQLTPVRKTEDTHQDEGVQLLPSKKQPPSVSPFGENIKQIFQWIFSKKKSKPAPVTAESQKTVKNRSCVYSSSAEAQGLMTAVGQMLDEKMSLCHARHASKVNQHKQKFQAPVCGFPCNHRHLFYSEHGRILSYAASSQQATLKSQGCPNRDRQIRNQQPLKSVRCNNEQWGLRHPQILHPKKAVSPVSPPQHWPKTSGASSHHHHCPRHCLLWEGI
What is the function of this protein?
May play a role in spermatogenesis.
What are the official names of this protein?
Spermatogenesis-associated protein 31A3, Protein FAM75A3.
What is the protein family that this protein belongs to?
Belongs to the SPATA31 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SHSA2_MOUSE
Sequence: MWGGRCSPSTSSRHRASLLQLLLAALLAAGARASGEYCHGWLDAQGVWRIGFQCPERFDGGDATICCGSCALRYCCSSAEARLDQGGCDNDRQQGVGEPGRTDREGPDSSAVPIYVPFLIVGSVFVAFIILGSLVAACCCRCLRPKQDPQQSRAPGANRLMETIPMIPSASTSRGSSSRQSSTAASSSSSANSGARAPPTRSQTNCCLPEGTMNNVYVNMPTNFSVLNCQQATQIVPHQGQYLHTPYVGYAVQHDSVPMTPVPPFMDGLQPGYRPVQPPFAHTNSEQKMFPAVTV
What is the function of this protein?
Plays an essential role in the maturation of presomitic mesoderm cells by individual attenuation of both FGF and WNT signaling.
What are the official names of this protein?
Protein shisa-2 homolog, Shisa-like protein 2, mShisa, Transmembrane protein 46.
What is the protein family that this protein belongs to?
Belongs to the shisa family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: TRPG_NEOYE
Sequence: MILIIDNYDSFTYNLAQCVGELGYDVLVCRNDEIDIPTIKQLNPNKIIISPGPGKPSDSGISLDVISSFSDSIPILGVCLGHQSIGYLNGGRIIKVSEIMHGKTSKIYHNNEDLFKTLPNPFIATRYHSLIIDNLNFPSSLAITAWTENNIIMACRHKDNQMLRGIQFHPESLWTFYGQQLLRNFLEYS
What are the official names of this protein?
Anthranilate synthase component 2, AS, Anthranilate synthase, glutamine amidotransferase component.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RER2_ENCCU
Sequence: MIEGLKVKALICVVEIIENGINSIHAMGILLFALNILKKASVLVSRILCAWNGKLSSEYPRDPRSRLGIFKNMNIAFICDGNRRYARKLGLEDSFIKDKGLQKIYEFIEFGCFYGIKEISFFCFALSNFKRSPEEVNKLMGLVKQKIERPKEIGIRPKFRVYGRLDLLEEDVRKRLMDIEEESKNNTSIIVNIFFAYSAEDEITRGIQFNSHVDILIRTSNTKRLSNFMIRQVAKGTSVFFAKALWPELTTAHLFLILLKHRLENKYLLG
What is the function of this protein?
Cis-prenyl transferase that adds multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP).
What are the official names of this protein?
Dehydrodolichyl diphosphate synthase, DEDOL-PP synthase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: MTLD_COCIM
Sequence: MGKKAVHFGGGNIGRGFVGEFLHESDYEVVFVDVMDSIIDALQGASSYKVTEVSNEGEHTKTVTNYRAINSKHNLDQVISEISTADVVTCAVGPNILKFIAPPIAKGIDARTIERPLAVVACENAIGATDTLHKFVKENTDPSRVESLSSRARFANSAIDRIVPTQDPDSGLDVKIEKFYEWVVEKTPFGEWGHPDIQAILWVDNLDPYIERKLYTVNTGHATAAYYGYNMGKKTIYESMSDEKIRGHVRDALSETSTLIVDKYGIPAQEQRKYVDAIVARISNPHLEDVVERVGRAPLRKLGRKERFVGPASQLAERGKKVDALLGAMEQALRFQNVLEDDESFELAKILKTESAEDATAKLTGLESDHPLFARVVERVAKVQKGPK
What is the function of this protein?
Catalyzes the NAD(H)-dependent interconversion of D-fructose 6-phosphate and D-mannitol 1-phosphate in the mannitol metabolic pathway.
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase, M1PDH, MPD, MPDH.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: ADCY9_CHICK
Sequence: MASPPHQQLLHHHSTEVSCDSSGDSNSVTVRINPRQQQALSAKRCKYSISSSCSSGESGGVGRGGGGGLRRQKKLPQLFERASSRWWDPKFDSTNLEEASMERCFPQTQRRFRYALFYIGSACLLWGIYFGVHMREKQMVFMVPALCFLLVCVAFFAFTFTKAYARRYVWTSGYTLLVFALTLAPQFQPWTLGERQRVQPRPAAPVDTCLSQVGSFSMCVEVLLLLYTVMHLPLYLSLFLGLSYSVLFETSAFRDESCTLLGGGAVYWELLSKAFLHVCIHAIGIHLFIMSEVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDDESENSVKRHSTSSPKNRKKKPSIQKTPIIFRPFKMQQIEQVSILFADIVGFTKMSANKSAHALVGLLNDLFGRFDRLCEDTKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIKAIEQFCQEKKEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLDDRYEMEDGKVTERVGQSAVADQLKGLKTYLISGQKVKEPHCSCSQALLQLGGWGWSQMQAAPSAENTADSTKALKHVEKPKPCPSCSTTLVPPCDVSIDEGAIQNGCQDEHKNSTKAPGGHSPKTQNGLLSPPQEEKLSNSQTSLYEMLQEKGRWGGVSLDQSALLPLRFKNIREKTDAHFVDVIKEDSLMKDYFFKPPISKLSLNFLDQDLEMAYRTSYQEEVMRNAPVKTFASATFSSLLDVFLSTTVFLILSVTCFLKHGMVASPPPPAAVVVFVIAILLEVLSLVISVRMVFFLEEVMACTKRLLELISGWLPRHFLGAILVSLPALAVFSHFTSDFETNIHYTMFMCCAILIAIVQYCNFCQLSSWMRSLLATVVGAVLLILLYVSLCPDSSVETLHLDLAQNLSSRKSPCNSSMPADVKRPADLIGQEVILAVFLLLLLVWFLNRSFEVSYRLHYHGDVEADLHRTKIQSMRDQPDSCVRNIIPYHVADELKVSQSYSKNHDSGGVIFASIVNFSEFYEENYEGGKECYRVLNELIGDFDELLSKPHYSSIEKIKTIGATYMAASGLNTSQCQDSNHPHGHLQTLFEFAKEMMRVVDDFNNNMLWFNFKLRIGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTIGVECRIQVSEETYRILSKMGYDFDYRGTVNVKGKGQMKTYLYPKCMDNGIVPHHQLSISPDIRVQVDGSIGRSPTDEIANLVPSVQNSDKTAHATDNSETKDALPSSKKLQKEPTKAEERCRFGKAVEKTDCEEAGTEEVNELTKLNVSKSV
What is the function of this protein?
Adenylyl cyclase that catalyzes the formation of the signaling molecule cAMP in response to activation of G protein-coupled receptors.
What are the official names of this protein?
Adenylate cyclase type 9, ATP pyrophosphate-lyase 9, Adenylate cyclase type IX, Adenylyl cyclase 9.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.
Protein: SPP2B_MOUSE
Sequence: MAAARLAAALLLLAAQVACEFGVLRVVSQTSRTRSRDYCILYNPQWAHLPHDLSKVSLLKLRDLSTTQLCSYLDVPAEDFTNQIALVARGNCTFYEKVRLAQGSGAHGLLIVSKEKLVPPGGNKTQYEEISIPVALLSHRDLQDIFRRFGREVMVALYAPSEPVMDYNMVIIFVMAVGTVAIGGYWAGSHDVKKYMKHKRDDGPEKQEDEAVDVTPVMICVFVVMCCFMLVLLYYFYDRLVYVIIGIFCLASSTGLYSCLAPFVRKLPFCTCRVPDNNLPYFHKRPQARMLLLALFCVTVSVVWGIFRNEDQWAWVLQDTLGIAFCLYMLKTIRLPTFKACTLLLLVLFIYDIFFVFITPFLTKSGNSIMVEVATGPSNSSTHEKLPMVLKVPRLNTSPLSLCDRPFSLLGFGDILVPGLLVAYCHRFDIQVQSSRIYFVACTIAYGLGLLVTFVALVLMQRGQPALLYLVPCTLLTSCTVALWRRELGAFWTGSGFAKDAPQTPWAATQGPVPPKAVGSSLSEQPPSEELAKSPLSTEEAGAADPAKDPDNPVASPLSPSNGDEAQPIPVVKPETSA
What is the function of this protein?
Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane.  Functions in ITM2B and TNF processing.  Catalyzes the intramembrane cleavage of the anchored fragment of shed TNF-alpha (TNF), which promotes the release of the intracellular domain (ICD) for signaling to the nucleus.  May play a role in the regulation of innate and adaptive immunity.
What are the official names of this protein?
Signal peptide peptidase-like 2B, SPP-like 2B, SPPL2b.
What is the protein family that this protein belongs to?
Belongs to the peptidase A22B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein; Lumenal side. Note=targeted through the entire secretory pathway to endosomes/lysosomes.
Protein: RIMP_CLOBJ
Sequence: MSKHSLIENLKKQIEPIAEGLDYELYHIEFVKEGKENYLRIYIDSENGVSLEGCEKVSRAISELLDDIDPIQESYYLEVSSPGIDRVLYTDKHLEKYKSYNIVLNLYSPIDKKKKYEGELVDFNENEIDIKVEENIVTIPREKISKTTLKGEL
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.