PharMolix/UniProtQA huggingface dataset:
Protein: QTRT2_DROPS
Sequence: MKFVIESLTKNSGRLGRLHIKDGAPGQRTPLLMQTTKGGSIPYLSADVFESHVTETPQLLELTLSTIDHMSEALAQWNSADRGLSDYIGFPGHLNVLLLRDPCETTPAGGNDRDIQPLFTRRGKESLSAQRYMEMVASLRPDIYQGLCDADTNAESAKKRVQKSVDRTEKFMHYIYEHKSKVDSTLLAPIVGGYNTFARTQSIKHALEQPSGSYGGYVFEGFHTNGLSATILDASKLLPIVEHCVGQLEEEKPRMVPGAYTPLTTLELIGLGMDLFDTSYAYCAAVNFKALTFTFVQDEVVHVPLLDITDDAIKEDFSPLLKNCDCLSCQKHTRAYVHHLYKTNELLGPILLMVHNLHHYMAFFEAIRESIARDGLPQLTELVRRQNGDSQVDYSIAPNRKVISKATMGKGFAAAAV
What is the function of this protein?
Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase accessory subunit 2, Queuine tRNA-ribosyltransferase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS5_RHOP5
Sequence: MAGERERGGRDRGPREERDSEFVDKLVHINRVAKVVKGGKRFGFAALVVIGDQKGRVGFGHGKAREVPEAIRKATESAKRNLTRVPLREGRTLHHDIAGRHGAGRVYLRAAPAGTGIIAGGPMRAVFETLGIQDVVAKSIGSSNPYNMVRATFDALKHQDSPRSVAARRNIKVSTLQSRRVGGDAEVVAE
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: NLPI_ECO8N
Sequence: MKPFLRWCFVATALTLAGCSNTSWRKSEVLAVPLQPTLQQEVILARMEQILASRALTDDERAQLLYERGVLYDSLGLRALARNDFSQALAIRPDMPEVFNYLGIYLTQAGNFDAAYEAFDSVLELDPTYNYAHLNRGIALYYGGRDKLAQDDLLAFYQDDPNDPFRSLWLYLAEQKLDEKQAKEVLKQHFEKSDKEQWGWNIVEFYLGNISEQTLMERLKADATDNTSLAEHLSETNFYLGKYYLSLGDLDSATALFKLAVANNVHNFVEHRYALLELSLLGQDQDDLAESDQQ
What is the function of this protein?
May be involved in cell division.  May play a role in bacterial septation or regulation of cell wall degradation during cell division (By similarity).
What are the official names of this protein?
Lipoprotein NlpI.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: DAPA_TERTT
Sequence: MYRGSMVALVTPMKADGSLDWDALHKLIDWHLEQGTHAIVAVGTTGESATLNMAEHLEVISKVVDQVNGRVPVIAGTGANSTSEALELTQGAKQAKADACLLVTPYYNKPSQEGLYQHYCYLAREVAIPQFLYNVPGRTAVDMLPETVARLATVENIVGIKDATASMERLQQMQALTDDSFIFLSGDDATSVDFMALGGHGEISVTANVVPAQTAKICELALAGNVEQARELDRPLAPLHEALFLEANPVPVKWAMARMGFLDGALRLPLTPLNAVYHAQLEAAMLSAGAI
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXS_FRAT1
Sequence: MSDINIKIGLAEMLKGGVIMDVVNAEQAEIAQQAGAVAVMALERVPADIRKDGGIARMSDPKLIKEIMSVVSIPVMAKARIGHFVEAQILESLGVDFIDESEVLTPADELNHIDKDSFKVPFVCGCTNLGEALRRIGEGAALIRTKGEAGTGNIVEAVRQLRQVNKDINYIKNADKSELMAIAKNLQAPYDLVTYVHKNGKLPVPNFSAGGVATPADAALMMQLGAESVFVGSGIFKSADPLKRARAIVSAVTYYNDAKILAEVSEDLGEPMTGINCDFEKFSQRGW
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: FNR_VIBCH
Sequence: MISEKPAAKRIQSGGCAIHCQDCSISQLCIPFTLNESELDQLDQIIERKKPIQKGQELFKAGDELRSLYAIRSGTIKSYTITEQGDEQITAFHLAGDLVGFDAITGDQHPSFAQALETSMVCEIPYEILDDLSGKMPKLRQQIMRLMSNEIKGDQEMILLLSKKNAEERLAAFLYNLSTRFSQRGFSPREFRLTMTRGDIGNYLGLTVETISRLLGRFQKSEILSVKGKYITILNHAELMELAGVSKESK
What is the function of this protein?
Global transcription factor that controls the expression of over 100 target genes in response to anoxia.  It facilitates the adaptation to anaerobic growth conditions by regulating the expression of gene products that are involved in anaerobic energy metabolism.  When the terminal electron acceptor, O(2), is no longer available, it represses the synthesis of enzymes involved in aerobic respiration and increases the synthesis of enzymes required for anaerobic respiration (By similarity).
What are the official names of this protein?
Fumarate and nitrate reduction regulatory protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AAR2_HUMAN
Sequence: MAAVQMDPELAKRLFFEGATVVILNMPKGTEFGIDYNSWEVGPKFRGVKMIPPGIHFLHYSSVDKANPKEVGPRMGFFLSLHQRGLTVLRWSTLREEVDLSPAPESEVEAMRANLQELDQFLGPYPYATLKKWISLTNFISEATVEKLQPENRQICAFSDVLPVLSMKHTKDRVGQNLPRCGIECKSYQEGLARLPEMKPRAGTEIRFSELPTQMFPEGATPAEITKHSMDLSYALETVLNKQFPSSPQDVLGELQFAFVCFLLGNVYEAFEHWKRLLNLLCRSEAAMMKHHTLYINLISILYHQLGEIPADFFVDIVSQDNFLTSTLQVFFSSACSIAVDATLRKKAEKFQAHLTKKFRWDFAAEPEDCAPVVVELPEGIEMG
What is the function of this protein?
Component of the U5 snRNP complex that is required for spliceosome assembly and for pre-mRNA splicing.
What are the official names of this protein?
Protein AAR2 homolog, AAR2 splicing factor homolog.
What is the protein family that this protein belongs to?
Belongs to the AAR2 family.
Protein: MRAZ_METSB
Sequence: MDGYVSHYTNKLDAKGRVSIPAPFRAVLVRDGFDGLYVHPSIDQEALDCGGHALLREIDGLLSGLSPYSEERDLFSTALIGTSEILKVDSEGRTILTETLKSYAGITGEVTFVGHGHKFQIWEPGRFRAHLEEARNRVRDLRRQLSARHAAPDAPPLRSHGARE
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: MURE_MYCLE
Sequence: MTEVVAVPVRLRPSATAGVRLPELVAQVGAVLADGPGQAATVPDIPVTGVTLRAQEVLSGDLFAALAGASTHGARYAGVALERGAVAVLTDVAGVAELTAQASSVPILIHPEPRSVLGGLAAAAYGHPSNRMTVVGITGTSGKTTTTYMVEAGLRAGGRVVGLVGTIGIRIDGADIPSFLTTPEAPALQAMLAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDMEEYFEAKAVLFDPHSLLRARTVVVCIDDDAGRATAARAGDAITVSALGQPASWRATDIRSPGVGAQEFTAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRIPGRLERIDCGQDFLALVDYAHKPGALHSVLTALLQPDHRLAVVFGAGGERDPGKRAPMGEIAAELADLVVVTDDNPRGEDPAAIRRDILTGTVAAGGAAQVVEIGDRRAAIQYAVAWAGPDDVVLVAGKGHETGQRGAAETCPFDDRVELARALQVRDARLLPAPGRACQ
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_BACCR
Sequence: MGQKVNPIGLRVGVIRDWESRWFAEKDYATLLHEDIKIREYINVRLKDSAVAKVEIERAANRVNVTIHTAKPGMVIGKGGTEVEALRKALNQLTGKRVHINILEVKRADLNAKLVGENIARQLENRVSFRRAQKQVIQRAMRAGAKGIKTQVSGRLGGADIARAESYSEGTVPLHTLRADIDYAAVEADTTYGKLGVKVWIYRGEVLPTKKKASEEGGK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: CD123_RAT
Sequence: MKKEHVSHCQFSAWYPLFRSLTIKSVILPLPQNVKDYLLDDGTLVVSGREDPPTCSQPDSGDEAEETQWSDDESTATLTAPEFPEFNTQVQEAINSLGGSVFPKLNWSAPRDAYWIAMNSSLKCKSLSDIFLLFKSSDFITHDFTQPFIHCNDDSPDPCIEYELVLRKWCELIPGAEFRCFVKENKLIGISQRDYTQYYDHISKQKEEICRCIQDFFKEHLQYKFLDEDFVFDIYRDSRGKVWLIDFNPFGEVTDSLLFTWEELTSENNLRGDVSEADALEQDSPAFRCTNSEVTVQPSPYLSYGLPKDFVDLSTGEDAHKLIDFLKLKRNQQEDD
What is the function of this protein?
Required for S phase entry of the cell cycle.
What are the official names of this protein?
Cell division cycle protein 123 homolog, Protein D123.
What is the protein family that this protein belongs to?
Belongs to the CDC123 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOLA_AERS4
Sequence: MKKQLLIGSVLLVASSQVWADAASSLKQKLADVSLFSAKFAQTVYDSKGKELQKAGGDLLVQRPNRFNWHTTSPDESLIVADGKDVWVYDPFVEQVTALKLKDAVLNTPFILIAGNDDKFWKHYDVTQEGNVYTVTSRNKDELIASFRVTFDRQNNISRFDVKEAQGQWSEFTLSSFNRKPVLKGNEFVFKIPKGVELDDQR
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: CNR14_CAEEL
Sequence: MSFETKPNYLLLTNPDTPLSVCTSPYYSPSGKTASIPSSEASKPEGTNGQWSHLPTGATYVTDEFSSEFQIQNGSTAAQSGNANNYADPLSHRRYFNNVNGYNHHQFYDTASQASVSSPATSVTSSLSPPDSLSNGHTTQRHHIGKAISFCKVCGDKASGYHYGVTSCEGCKGFFRRSIQRKIDYRCLKQQVCEIKRESRNRCQYCRFKKCLDSGMSKDSVRQMKFRNAMRDDKSPDSVFVPEISTLERQEEVDAVYEAVLRAHTTFSFYTDIKIRSIVARPFNVRINEDSKMNRLNAWQIYAHEIDVDIKEVVNFVKEIPKFNFINGNDKAVLLRKNAFPLYLLRIVRGMSNRGLMLRDGRLIDFKSLQLLYGSLADEMLAFANHIITIGCTDGDIALFIVLILCQPLTTEQQFSTNFKSQLQLLEMFDFYKKVLFQKMTCRIDGCDTYKQLMKCIHELNRLNELHKQQLNILRENLSFLNLPPLVVEMFQLSTLPLPVNHNNQENQYTPAPEHQSPQPQQPTPNQQQTPVHC
What is the function of this protein?
Transcriptional regulator which is involved in the sex determination and X chromosome dosage compensation pathways (PubMed:21471153, PubMed:23666922, PubMed:16139225, PubMed:17720939, PubMed:33372658).  Directly binds to five 5'-A(G/C)(G/T)(T/G)C(A/G)-3' sites in the promoter of sex-determining factor xol-1 to negatively regulate its expression and promote hermaphrodite development (PubMed:23666922).  Together with fox-1 is involved in making the distinction between one and two X-chromosomes (PubMed:21471153, PubMed:23666922, PubMed:33372658).  Plays a role in the fox-1-mediated repression of the functionally active isoform (isoform b) of the sex-determining factor xol-1 gene to promote hermaphrodite development (PubMed:33372658).  Plays a role in the association of the dosage compensation complex proteins dpy-27 and sdc-3 with the hermaphrodite X chromosomes (PubMed:16139225, PubMed:17720939).
What are the official names of this protein?
Steroid hormone receptor family member cnr14, Nuclear receptor subfamily 1 group G member 1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PEN2_RAT
Sequence: MNLERVSNEEKLNLCRKYYLGGFAFLPFLWLVNIFWFFKEAFFAPAYTEQSQIKGYVWRSAVGFLFWVIVLTTWITIFQIYRPRWGALGDYLSFTIPLGTP
What is the function of this protein?
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein).  The gamma-secretase complex plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels.  PSENEN modulates both endoproteolysis of presenilin and gamma-secretase activity.
What are the official names of this protein?
Gamma-secretase subunit PEN-2, Liver regeneration-related protein LRRGT00140, Presenilin enhancer protein 2.
What is the protein family that this protein belongs to?
Belongs to the PEN-2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus, Golgi stack membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Note=Predominantly located in the endoplasmic reticulum and in the cis-Golgi.
Protein: DAAF4_PONPY
Sequence: MPLQVSDYSWQQTKTAVFLSLPLKGVCVRDTDVFCTENYLKVNFPPFLFEAFLYAPIDDESSKAKIGNDTIVFTLYKKEAAMWETLSVTGVDKETMQRIREKSILQAQERAKEATEAKAAAKREDQKYALSVMMKIEEEERKKIEDMKENERIKATKELEAWKEYQRKAEEHKKIQREEKLCQKEKQIKEERKKLKYKSLTRNSASRNLAPKGRNSENIFTEKLKEDSIPAPRSVGSIKINFTPRVFPTALRESQVAEEEEWLHKQAEARRAMNTDIAELCDLKEEEKNPEWLKDKGNKLFATENYLAAINAYNLAIRLNNKMPLLYLNRAACHLKLKNLHKAIEDSSKALELLMPPVTDNANARMKAHVRRGTAFCQLELYVEGLQDYEAALKIDPSNKIVQIDAEKIRNVIQGTELKS
What is the function of this protein?
Involved in neuronal migration during development of the cerebral neocortex.  May regulate the stability and proteasomal degradation of the estrogen receptors that play an important role in neuronal differentiation, survival and plasticity.  Axonemal dynein assembly factor required for ciliary motility (By similarity).
What are the official names of this protein?
Dynein axonemal assembly factor 4, Dyslexia susceptibility 1 candidate gene 1 protein homolog.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell projection, neuron projection. Dynein axonemal particle.
Protein: RL2_BORPE
Sequence: MALVKVKPTSAGRRGMVKVVSPKLHKGAPHAALLEKKTRGSGRNNNGHITVRHRGGGHKQHYRVVDFRRNKDGIPAKVERLEYDPNRTAHIALLCYADGERRYIIAPRGLEVGATLISGIEAPIRAGNTLPIRNIPVGTTIHCIEMIPGKGAQMARSAGASAVLMAREGTYAQVRLRSGEVRRVHIQCRATIGEVGNEEHSLRQIGKAGAMRWRGVRPTVRGVAMNPIDHPHGGGEGRTGEAREPVSPWGTPAKGFKTRRNKRTNNMIVQRRKRK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: GPMA_DESVM
Sequence: MHTLVLLRHGQSAWNLENRFTGWTDVDLSPEGEQEARDAARLLTDEGLTFDVCHTSVLTRAIRTLYIVQHEMGLSWLPVHKHWRLNERHYGGLQGLDKAETAARFGEEQVFEWRRSYDTPPPPLPADDPRSPAGDARYAGLAPDVLPASESLKETVARVLPYWHDVIAPQVLAGQRVLVAAHGNSLRALVMHLDGMTPEAVTKLNIPTGLPLVYTLDGTLRPLAHRYLGDPAVAEAKAKAVAAQGAARK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: RF1_EHRRW
Sequence: MSFDSGLEELSEKFYKLKHLLEDPSQLSVESFVNASKEYSELLPIISVIDEYNAVQKDIKDLQELINNQETDTELKNLAKEEFYELQKQLPKVKHKLKLSLLPKDKDDARNAILEIRAGTGGEEAALFVTDLYRMYIKYAEKKNWKIEQINSSSTGIGGHKEVSLCVSGSNVFAKLKFESGVHRVQRVPETEASGRLHTSAATVAVLPEIEEVDLKIDEKDLRIDVYRSSGPGGQSVNTTDSAVRITHIPSGIVVIQQDEKSQHKNKNKALKVLRARLYDLEKQKRDAEISQLRKSQIGSGDRSERIRTYNFPQSRITDHRINLTLYRLEDIMKEGDLDELIEALIAEDEANKLKNLNI
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2027_YERE8
Sequence: MLKASLLFFVTALAEIIGCFLPYLWLRKGASMWLLLPAAASLALFVWLLTLHPAASGRVYAAYGGVYVATALIWLRVVDDVKLSLFDWVGAAVALVGMLIIVAGWRVN
What are the official names of this protein?
UPF0060 membrane protein YE2027.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LEU1_XANOM
Sequence: MNTTISNQTPHIRIFDTTLRDGEQSPGCSMTPQQKLVMARALDELGVDIIETGFPASSHSDREAVAMMGRELRRPTLAVLSRCLQADIETSAKALETAANPRLHVFLSTSPLHREHKLRMSREQVLESVHRHVTLARGYIDDVEFSAEDATRTEEDFLAEVTRVAVAAGATTINLPDTVGFTTPEEIRGMFSRLIASVEGADKVIFSAHCHNDLGLAVANSLAAIEGGARQVECTINGIGERAGNCALEEITMALKVRGAFYNIDSAINTPRIVSTSQLLQRLVGMPVQRNKAVVGGNAFAHESGIHQHGMLRHRGTYEIMRPEDVGWESSQMVLGRHSGRAAVERRLRALGYLLEEEEVKLMFEQFKALCEKQRLVTDADLQALMQDATVQEGYRLASMTISDVGSRANALVELSDPEGNRVAETAQGNGPVDALFGALASATGVKLELDSYQVHSVGIGADARGEASLSVRHDGVEYEGTGTSKDIIEASALAWLDVANRLLRQRERGVIAGKTAAVA
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: DXR_ANAMM
Sequence: MLHMGRKRVSVFGSTGCIGQKAVQILRDNPDDFEVVALVAKQDAHLLASQARLLSANMAVVAEDAAYETLRELLRGTCVEVGAGTAGVMDAASRDVDSAVMAITGIAALHPVIRLIKSGVKSIALANKESVVCGGELLINAAKQTGVNIVPVDSEHNAVFQILAHDGCVARVTLTASGGPFLRWTREQMQAVTPSDALAHPVWKMGRKISVDSATMVNKALEVIEAHYLFSLDPDSIDVTVHPESVVHAVAAYPNGTSISLMSVPDMGIPTLHALYWPQSATVCGSTLDLASYGKLTFMEPDLERFPALGFGFEALRSSKPRAACIALNAANEVAVEAFLNFEIAFLDIPNIIMSAMDKLACCEVNSISEAGEYDLICRARTREICDTLKVSEFIR
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: LRK12_ARATH
Sequence: MAQRFYLLLLLLIFLVNLICFSSQQDLSFVFNGFNQDQAGDELLLDGFARIQSPERVLQLTDGTTQQKGHAFFNRPFDFGSASSQSLSFFTQFVCALVPKPGFYGGHGIAFVLSSAHNLKKAYASSYLGLFNRSTNGSPSSHVLAVELDTVQSAETDDMDNNHVGIDENRIQSVVSASASYYSDREGKNISLILLSGDPIQVWVDYEDTLLNVTLAPLRNQKPSKPLLSRTINLTAIFPDRKAFVGFSAATGSSISNQYILGWSFSRSRRLLKSLDISELSTVPLFTEQKRKRSPLLIVLLVILTLVVIGGLGGYYLYRRKKYAEVREPWEKEYGPLRYSYESLYKATKGFNKDGRLGKGGFGEVYKGSLPLVGDIAVKRLSHNAEQGMKQFVAEVVTMGSLQHKNLVPLLGYCRRKGELLLVSKYMEGGSVDQYLFNGDKPPLSWSQRLAILRDIASALCYLHTGASQVVLHRDIKASNVMFDDHGANLSATAAVGTIGYMALELISTGTSTKTDVYAFGAFMLEVTCGRRPFDPEMPVEKRHLVKWVCECWRKHSLVDAIDTRLRDKFTLGEVEMVLKLGLLCTSIIPESRPNMEKVMQYINRDQALPDFSPDTPGIGVSTPMVMGIPGLAITSTSVTSSASVPLVSPPSTNNSMFISHTILNGDGR
What is the function of this protein?
Involved in resistance response to the pathogenic fungus Alternaria brassicicola.
What are the official names of this protein?
Probable L-type lectin-domain containing receptor kinase I.2, LecRK-I.2.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the leguminous lectin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: EFG2_SHESR
Sequence: MTELSKYRNIGIFAHVDAGKTTTTERILKLTGKIHKLGEVHDGESTTDFMVQEAERGITIQSAAVSCFWKDHRFNVIDTPGHVDFTVEVYRSLKVLDGGIAVFCGSGGVEPQSETNWRYANESEVARIIFVNKLDRMGADFLRVVKQTKDVLAANPLVMVLPIGIEDEFKGVVDLLTRKAYVWDDSGIPENFEVQDVPADMVDLVEEYREMLIESAVEQDDDLMEAYMEGEEPSIEDLKRCIRKGTRTMAFFPTFCGSAFKNKGMQLVLDAVVDYLPAPDEVDPQPLTDEEGNETGEYAIVSADESLKALAFKIMDDRFGALTFVRIYAGRLKKGDTILNSATGKTERIGRMCEMYANDRIEIESAEAGDIIAIVGMKNVQTGHTLCDVKHPCTLEAMVFPEPVISIAVAPKDKGGSEKMAIAIGKMIAEDPSFRVETDEDSGETILKGMGELHLDIKVDILKRTYGVELIVGEPQVAYRETITQMVEDQYTHKKQSGGSGQFGKIEYIIRPGEPNSGFVFKSSVVGGNVPKEYWPAVEKGFASMMNTGTIAGFPVLDVEFELTDGAYHAVDSSAIAFEIAAKAAFRQSIAKAKPQLLEPIMKVDVFSPEDNVGDVIGDLNRRRGMIKDQVAGVTGVRVKADVPLSEMFGYIGTLRTMTSGRGQFSMEFSHYSPCPNSVADKVVEQVKERKAAEAKK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G 2, EF-G 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CD3D_BOVIN
Sequence: MEHSRFLSCLILAALLSQVNPRILKVLEPEDKVMLECNSSITLLQGTEGQEVSGNNKTRDLGKRIQDPRGMYRCGENTQQLILQVYYRMCQNCVELDTATLAGMIITDIIATVLLALGVYCFAGHETGRFSRAADTQALMGNDQLYQPLRERNDAQYSRLGDKWARNK
What is the function of this protein?
Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response.  When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z.  All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain.  Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways.  In addition of this role of signal transduction in T-cell activation, CD3D plays an essential role in thymocyte differentiation.  Indeed, participates in correct intracellular TCR-CD3 complex assembly and surface expression.  In absence of a functional TCR-CD3 complex, thymocytes are unable to differentiate properly.  Interacts with CD4 and CD8 and thus serves to establish a functional link between the TCR and coreceptors CD4 and CD8, which is needed for activation and positive selection of CD4 or CD8 T-cells.
What are the official names of this protein?
T-cell surface glycoprotein CD3 delta chain, T-cell receptor T3 delta chain.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: HDOX_BACAN
Sequence: MIIVTNTAKITKGNGHKLIDRFNKVGQVETMPGFLGLEVLLTQNTVDYDEVTISTRWNAKEDFQGWTKSPAFKAAHSHQGGMPDYILDNKISYYDVKVVRMPMAAAQ
What is the function of this protein?
Allows bacterial pathogens to use the host heme as an iron source.  Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the biliverdin in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron.
What are the official names of this protein?
Heme-degrading monooxygenase, Heme oxygenase, Iron-regulated surface determinant, Iron-responsive surface determinant.
What is the protein family that this protein belongs to?
Belongs to the antibiotic biosynthesis monooxygenase family. Heme-degrading monooxygenase IsdG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_BRUA1
Sequence: MNSIPEGRPTPNLPRTANKRGVARLAAVQALFQMDVAGTGVMEVVAEYEAFRLGKEVDGTQYLDADPQWFRAIVAGVVEDQLKLDPMIHQALTEDWPLSRLDSTLRAILRAGAWELKARKDVPTAVIVSEYVDIAKAFYTEDEPKLVNAVLDRLALVIRGESRGAKPRHKS
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.