PharMolix/UniProtQA huggingface dataset:
Protein: MNME_ECODH
Sequence: MSDNDTIVAQATPPGRGGVGILRISGFKAREVAETVLGKLPKPRYADYLPFKDADGSVLDQGIALWFPGPNSFTGEDVLELQGHGGPVILDLLLKRILTIPGLRIARPGEFSERAFLNDKLDLAQAEAIADLIDASSEQAARSALNSLQGAFSARVNHLVEALTHLRIYVEAAIDFPDEEIDFLSDGKIEAQLNDVIADLDAVRAEARQGSLLREGMKVVIAGRPNAGKSSLLNALAGREAAIVTDIAGTTRDVLREHIHIDGMPLHIIDTAGLREASDEVERIGIERAWQEIEQADRVLFMVDGTTTDAVDPAEIWPEFIARLPAKLPITVVRNKADITGETLGMSEVNGHALIRLSARTGEGVDVLRNHLKQSMGFDTNMEGGFLARRRHLQALEQAAEHLQQGKAQLLGAWAGELLAEELRLAQQNLSEITGEFTSDDLLGRIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_BRUME
Sequence: MSNTVSLQFPDGSVREYDASMTGAALAESISKSLAKKAVAYAVDGTVRDLSDPLGASGKVEIITREDPRALELIRHDTAHVLAEAVQELFPGTQVTIGPVIENGFYYDFARNEPFTLDDLPVIEKKMREIIQRNKPFTKEVWSREKAKQVFSDKGESYKVELVDAIPAGQDLKIYYQGDWFDLCRGPHMASTGQIGNSFKLMKVAGAYWRGDANNPMLTRIYGTAFANDNDLQAYLHMLEEAEKRDHRRLGREMDLFHFQEEGPGVVFWHAKGWKMFQNLVSYMRRRLDSHGYQEVNTPQVLDKSLWETSGHWGWYRDNMFKVTVAGDDTDDDRVFALKPMNCPGHVQIFKHGLKSYRDLPIKLAEFGNVHRYEPSGALHGLMRVRGFTQDDAHIFCTEEQMAAECLQINDLILSVYKDFGFEEITIKLSTRPEKRVGSDELWDRAESVMMTVLEQIRQQSNNIKTGILPGEGAFYGPKFEYTLKDAIGREWQCGTTQVDFNLPERFGAFYIGADSEKKQPVMIHRAICGSMERFLGILIENFAGHMPLWFAPVQVVVATITSDADEYAKEAAAKLKAAGLQVVTDLRNEKINYKVREHSLQKVPVILVCGKREAEEKTVNMRRLGSRDQESMTLDEAIARLCEEATPPDLLRLKNAG
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NKX21_HUMAN
Sequence: MSMSPKHTTPFSVSDILSPLEESYKKVGMEGGGLGAPLAAYRQGQAAPPTAAMQQHAVGHHGAVTAAYHMTAAGVPQLSHSAVGGYCNGNLGNMSELPPYQDTMRNSASGPGWYGANPDPRFPAISRFMGPASGMNMSGMGGLGSLGDVSKNMAPLPSAPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQQLQQDSGGGGGGGGTGCPQQQQAQQQSPRRVAVPVLVKDGKPCQAGAPAPGAASLQGHAQQQAQHQAQAAQAAAAAISVGSGGAGLGAHPGHQPGSAGQSPDLAHHAASPAALQGQVSSLSHLNSSGSDYGTMSCSTLLYGRTW
What is the function of this protein?
Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor.  Crucial in the maintenance of the thyroid differentiation phenotype.  May play a role in lung development and surfactant homeostasis.  Forms a regulatory loop with GRHL2 that coordinates lung epithelial cell morphogenesis and differentiation.  Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression.  Represses the transcription of the circadian transcriptional repressor NR1D1 (By similarity).
What are the official names of this protein?
Homeobox protein Nkx-2.1, Homeobox protein NK-2 homolog A, Thyroid nuclear factor 1, Thyroid transcription factor 1, TTF-1, Thyroid-specific enhancer-binding protein, T/EBP.
What is the protein family that this protein belongs to?
Belongs to the NK-2 homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: VCR_ARATH
Sequence: MASSPGNTNPHNPPPFDLGTIFKPSSNPYPPPTGPFLNNQYNQQLYAPPGIAAQPSPVNQTQQDVSSSSSATNLQPQRTLSYPTPPLNPQSPRVNHNPGTHILALLNNGGAVANQEPSHHNEIARAFPGGSGPIHVPSGKMPKGRRLVGEHAVYDVDVRLQGEIQPQLEVTPITKYGSDPQLVLGRQIAVNKVYICYGLKGGSIRVLNINTALRSLFRGHSQRVTDMAFFAEDVHLLASVSLDGKVFVWKISEGSEGDEQSQITGKIVVALQILGEEDTKHPRVCWHCHKQEILVVSIGKHVLRIDTTKVGRGEVFSAEAPLQCHLDKLIDGVQIVGKHDGEVTDLSMCQWMTTRLVSSSVDGTVKIWQDRKTQPLVVLRPHDGLPVNSAIFVTSPERPDHIILITGGPLNREIKIWVSAGEEGWLLPADTESWRCTQTLDLKSSTEPQAEKAFFNQVIALSEAGLLLLANARRNAIYSVHLDYGSSPVETLMDYLSEFTVTMPILSFIGTNDHPEEPFVKVYCVQTLAIQQYTLDLFLCMPPPRENVGFEKSDSTVSREANLVESTLETSGMKPTELPSVGSVPKPSILVNRSENANMLSFPAGPASAGITPPAIVPPNGEPKTSGMPSETSDVDSAYAPSPQLPLSPRLSSKLSGYHTPVEAFEQVLPHHKLGGKTSSADYFYVRQTDDVGGRNLDVSSVEENCRSKDTNVTPDDDVSGIRSPSAFFKQPTHLVTPSEILMGVSSTEASITTEDKRDRDANIEEVNNDARGLEVELKEVGEAQTSQNGEINYHETTENHTSESRENIFCSQASNLSTEMARDRHPITEGSAIPGDSMAYGQPLQAGDERGLDSRDVSAKLPESGSSSGLVATNSKGKKQKAKNSQGPGLSSTSSNVANLADSFNEQSQSLNHPMADLLPQLLALQETMTQVMASQKEMQRQLSNAVTGPIVKEGKKLEVALGRMIEKSSKSNADALWAHFQEEAVKNEKALRDHGQQIMNETTNFTSKELNAMFEKTMKKEFASVGPTLARVVTPVIEKTVSSAITESFQRGIGDKAVNQLEKSVNSKLETTVARQIQAQFQTSGRQVLQEGLRSSMESSVIPSFERSCKTMFEQVDSTLQKGIGKHTSATQQRIDSGQSQLAHTLRETISSASSVTQALNRELAESQRNRLALTAAGSNPLVTQLSNGPLGALLEKVEAPMDPTTELSRLISERKYEESFTSALQRSDVSIVSWLCSQVDLRGLLAMNPLPLSQGVLLSLLQQLACDISTDTSRKLGWMTDVVTAINPSDQMIAVHARPIFEQVYQILHHHRNAPGSDVSAVRLIMHVINSLLMSCK
What is the function of this protein?
As a component of the decapping complex, may play a role in the degradation of mRNAs.
What are the official names of this protein?
Varicose-related protein.
What is the protein family that this protein belongs to?
Belongs to the WD repeat EDC4 family.
What are the subcellular locations of this protein?
Cytoplasm, P-body.
Protein: RL16_AROAE
Sequence: MLQPSRRKYRKEQKGRNTGIATRGAKVSFGEFGLKAIGRGRLTARQIESARRAMTRHIKRGGRIWIRIFPDKPISKKPAEVRMGNGKGNPEYWVAEIQPGKVLYEMDGVDETLAREAFRLAAAKLPLETVFVHRQMG
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: AP4AT_RAT
Sequence: MAAVPPLRDRLSFLHRLPILLKGTSDDDIPCPGYLFEEIAKISHESLGSSQCLLEYLLNRLDSSSGHVKLKVLKILLYLCSHGSSSFMLILRRNSALIQEATAFAGPPDPLHGNSLYQKVRAAAQDLGSTLFSDALPQPPSQPPQILPPAGMGAQARPHSALQGFGYTKESSRTGSAGETFLSTIQRAAEVVVNAVRPGPDNPCTKGPLPHGDAYQPAVTPSASHTHPNPGNLLPAAIQGTRAVKHQPGQAGGGWDEMDSSPSSQNSSCTSNLSRASDSVSRSGSDSHSGASREPGDLAERAEGMAPNDCQQELNLVRTVTQGPRVFLSREETQHFIKECGLLNCEAVLELLLQQLVGTSECEQMRALCAIASFGSADLLPQEHILLLCRQQLQELGAGSPGPVTNKATKILRHLEASCGQQFPTLRPCAQPNSAAAVVGPADLLTSPVPPPGSQVFLQPLSSTAVVPRSPVPTPSPDTLPPALQDPGELRTQLVCSSEPGTGSEQRLENTDTPKDSSSPCPWSPNSLFAGMELVACTRLPCPSFQADLQKVTTEPPVSEPSAFAFLNM
What is the function of this protein?
Associates with the adapter-like complex 4 (AP-4) and may therefore play a role in vesicular trafficking of proteins at the trans-Golgi network.
What are the official names of this protein?
AP-4 complex accessory subunit Tepsin, ENTH domain-containing protein 2, Tetra-epsin.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Cytoplasmic vesicle. Cytoplasm, cytosol. Note=Extensively colocalizes with AP-4 which mediates the recruitment of TEPSIN to the trans-Golgi network.
Protein: MFNA_METS3
Sequence: MEDKPISKKDILKELNEIQSKDHKYSDGRILGSMCTEAHPFAKEVYCKFLDSNLGDPGLFKGTKYIENEVIKSIGELLSISEPYGNIVTGGTEANIMAMRAARNHARKYKGIKEGEIIIPDSAHFSFKKAADMMNLKIIEAKLDENYKIDVDSVKENISDNTVAIVAIAGTTELGLVDPIEELSEIAYENNIYFHVDAAFGGFSIPFLRKIGYEFPPFDFSLPGVCSITVDPHKMGLAPIPAGGILFRKKEYLEVMAVDSPYLTVKTQSTIVGTRSGAASAATYAIMKYLGNEGYEKLAGNLMDNTHYFKEGLEKIGYDVVVEPELNIVAFNHPDMEAHDLADKLEDLGWRVSVAKCPIAIRVVLMNHITKQHLTDLLDDLTEIY
What is the function of this protein?
Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis.  Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis.
What are the official names of this protein?
Probable L-tyrosine/L-aspartate decarboxylase, TDC/ADC.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family. MfnA subfamily.
Protein: RL32_LACGA
Sequence: MAVPARKTSKQKKRSRRGHIKLATPAMHYDATTGEYRLSHRVSPKGFYKGRQVANENKQQNND
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: LIPA_BACCR
Sequence: MTKQTEYKRKPEWLKIKLNTNENYTGLKKMMRSKNLHTVCEEAKCPNIHECWAVRKTATFMILGAVCTRACRFCAVKTGLPTELDLQEPERVADSVVQMGLKHVVITAVARDDLKDGGAAVFAETVRAVRRKNPFTSIEVLPSDMGGVEENLKMLMDAKPDILNHNIETVRRLSDRVRARAKYERSLEFLRRAKEMQPDIPTKSSIMVGLGETREDLIEAMDDLRANNVDILTLGQYLQPSKKHLPVLKYYPPAEFAELKEIALSKGFSHCEAGPLVRSSYHADEQVRSAKEKTAGS
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRP54_NATPD
Sequence: MVLDDLGSSLRGTLDKLQGKTTLSEDDVEEIVKEIQRSLLSADVDVDLVMDLSDSIRERALDEEPPAGTTARDHVLKIVYEEMVELVGESTALPLEEQTIVLAGLQGSGKTTTAAKMAWWFSKKGLRPAVIQTDTFRPGAYDQAKEMCERAEVDFYGNPDSDDPVEIAERGLEETADADVHIVDTAGRHALEEALIDELEAIESAVDPDRNLLVLDAAIGQGAKDQAERFHDAVGIDGVAITKLDGTAKGGGALAAVDQTDSSIAFLGTGEEVKDIERFEPSGFISRLLGMGDLKQLSERVERAMEETQAEEDWDPEDLMKGEFTLKDMRNQMNAMNKMGPLDQVMDMIPGLGGGIKDQLPDDAMDMTQERLRDFEVIMDSMSEAELENPRAIGQSQIERIARGSGTDEDTVRELLEQHKMMSRMMKQFQGMGDGDMQRMMKQMQQGGGGGGGGGGGLGGMGPFGD
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes.  The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
What are the official names of this protein?
Signal recognition particle 54 kDa protein, SRP54.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. SRP54 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=The SRP-RNC complex is targeted to the cytoplasmic membrane.
Protein: CH60_CALS8
Sequence: MAAKMILFDEEARRALERGVNKLADTVKVTLGPKGRNVVLEKKFGSPQIVNDGVTIAKEIELEDPFENMGAQIVREVASKTNDIAGDGTTTATVLAQAMIREGLKNIAAGANPMILRRGIQKAVDVVVDEIKKMSKKVRGKEDITYVASISAGDEEIGKLVADAMEKVTNDGVITVEESKTTETTLEIVEGMQFDRGYISAYMVTDTERMEAVLDDPYILITDKKISTIQDILPLLEQIVQQGKKLLIIAEDVEGEALATLVVNKLRGTLQCVAVKAPGFGDRRKAMLQDIAILTGGQVISEELGLDLREVKISQLGRARQVKVQKENTIIVDGAGDPSEIKARIQSIKKQIEETTSDFDREKLQERLAKLAGGVAVIHVGAATETEMKEKKLRIEDALAATKAAVEEGIVPGGGTAFINAIPALDKLIETLTGDEKTGAMIVKKALEEPLRQIAENAGLDGSVIVNKVKESPAGIGFDALNERFVDMFEAGIVDPTKVTRTAIQNAASAAAMLLTTEAVVAEKPEKEKNPPAPAPDMY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_LEPIC
Sequence: MARRCEVTGRGTVSGNNVSHSHIKTRRTWKVNLIKKRIFLEDENRWVTIRLSTRALRTLRKKGIKAAIKDNGGSLGVLAPKKYAGITKQAPKKA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: MI25_TOBAC
Sequence: MRLSSTNMQARKMLFAAILSICASSSKKISIYNEEMIVALCFIGFIIFSWKSLGKTFKVTLDGRIQAIQEESQQFPNPNEVVPPESNEQQRLLRISLRICGTVVESLPMARCAPKCEKTVQALLCRNLNVKSATLPNATSSRRIRLQDDIAIKMHVLVGKRFCPWCSSKAERVEFIRESLVVLRMVWVGDSLKNKELE
What is the function of this protein?
This is one of the chains of the nonenzymatic component (CF(0) subunit) of the mitochondrial ATPase complex.
What are the official names of this protein?
ATP synthase protein MI25, ORF 25.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein MI25 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: HSLO_METFK
Sequence: MQISDHLHRFLFENTPVRGSIVHLDDSFQQSLQHHDFPQILRQALGELMAASALLAATLKLKGGALVLQVQGKGPLKLLVVECTSDLGIRATAKWSGELDGMSFSDMVSNGHFVITLDPRDGGQPYQGIVPVEGGSIAEILQSYMQRSEQIDTRMWLACDGKRAAGMLVQKMPDQPDAADPDAWNRIIMLADTVRDEELLDLSAVSLIKRLFNEEDVRLFKEQPIKFHCGCSRESVGNMLRMLGEEEVADILAEQHTIDINCDFCNAEYHFDEVDAEQLFTTEIVMPGNDVRH
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_RHOPT
Sequence: MPKLKTKSGAKKRFKVTATGKVMSAQRGKRHGMIKRTKKQIRQLRGTRAIFKTDGDNIKKYFLPNA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: H2A_MAIZE
Sequence: MDSTGTGAGGKGKKGAAGRKVGGPRKKSVSRSVKAGLQFPVGRIGRYLKKGRYAQXVGTGAPVYLAAVLEYLAAEVLELAGNAARDNKKTRIIPRHVLLAIRNDEELGKLLGGVTIAHGGVLPNINPVLLPKKTAEKASSGGSKEAKSPKKAAKSPKKA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: PROB_ECOK1
Sequence: MSDSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHRIVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQMLLTRADMEDRERFLNARDTLRALLDNNIVPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLTDQKGLYTADPRSNPQAELIKDVYGIDDALRAIAGDSVSGLGTGGMSTKLQAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAGEITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDALRRIAGHHSQEIDAILGYEYGPVAVHRDDMITR
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXT_METMJ
Sequence: MGVKVGVLALQGDVAEHIAAFREALAERPGSSVAPIRRAEDLADLDALAIPGGESTTISRLMGKNGLYEPVAEFEGGVFATCAGMVLSADRVDDPRVRPLSLIPMHVARNAFGRQVDSRETMLEVAGLAEPFRAVFIRAPVATEAGDGVEVLARIPEGIVAVRHGRHMAFAFHPELGGDLRLHRVFLEGLEV
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: Y882_MYCTO
Sequence: MNDQRDQAVPWATGLAVAGFVAAVIAVAVVVLSLGLIRVHPLLAVGLNIVAVSGLAPTLWGWRRTPVLRWFVLGAAVGVAGAWLALLALTLGDG
What are the official names of this protein?
Uncharacterized protein MT0905.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GSA_PSEE4
Sequence: MSRSEALFAQAQKHIPGGVNSPVRAFKSVGGTPLFFKHAEGAYVIDEDDKRYVDYVGSWGPMILGHGHPEVLDAVRNQLQHGLSYGAPTAMETEMADLVCSIVPSMEMVRMVSSGTEATMSAIRLARGYTGRDAIIKFEGCYHGHSDSLLVKAGSGLLTQGVPSSAGVPADFAKHTLTLPFNDIAAVEKTLAEVGQTVACIIVEPVAGNMNCVPPAPGFLEGLREQCDKHGVVLIFDEVMTGFRVSLGGAQGYYGITPDLSTFGKIVGGGMPVGCFGGKREIMGCIAPLGPVYQAGTLSGNPLAMAAGLTTLKLISRPGFHDELTAFTSRMLDGLQQRADAAGVPFVTTQAGAMFGLYFSGADDIVTFDDVMASDAERFKRFFHLMLEGGVYLAPSAFEAGFTSIAHGDKELQITLDAAERAFAKLK
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AGBR_MYCTO
Sequence: MRFVVTGGLAGIVDFGLYVVLYKVAGLQVDLSKAISFIVGTITAYLINRRWTFQAEPSTARFVAVMLLYGITFAVQVGLNHLCLALLHYRAWAIPVAFVIAQGTATVINFIVQRAVIFRIR
What is the function of this protein?
Required for arabinosylation of arabinogalactan (AG), an essential component of the mycobacterial cell wall.  Probably acts as an anchor protein recruiting AftA, the first arabinosyl transferase involved in AG biosynthesis.
What are the official names of this protein?
Arabinogalactan biosynthesis recruiting protein MT3897.
What is the protein family that this protein belongs to?
Belongs to the GtrA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UTR1_YEAST
Sequence: MKENDMNNGVDKWVNEEDGRNDHHNNNNNLMKKAMMNNEQIDRTQDIDNAKEMLRKISSESSSRRSSLLNKDSSLVNGNANSGGGTSINGTRGSSKSSNTHFQYASTAYGVRMLSKDISNTKVELDVENLMIVTKLNDVSLYFLTRELVEWVLVHFPRVTVYVDSELKNSKKFAAGELCEDSKCRESRIKYWTKDFIREHDVFFDLVVTLGGDGTVLFVSSIFQRHVPPVMSFSLGSLGFLTNFKFEHFREDLPRIMNHKIKTNLRLRLECTIYRRHRPEVDPNTGKKICVVEKLSTHHILNEVTIDRGPSPFLSMLELYGDGSLMTVAQADGLIAATPTGSTAYSLSAGGSLVCPTVNAIALTPICPHALSFRPIILPESINLKVKVSMKSRAPAWAAFDGKDRIELQKGDFITICASPYAFPTVEASPDEFINSISRQLNWNVREQQKSFTHILSQKNQEKYAHEANKVRNQAEPLEVIRDKYSLEADATKENNNGSDDESDDESVNCEACKLKPSSVPKPSQARFSV
What is the function of this protein?
Specifically phosphorylates NAD in the presence of ATP, dATP, or CTP as phosphoryl donors.
What are the official names of this protein?
NAD(+) kinase, Unknown transcript 1 protein.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
Protein: CYC2_CERCA
Sequence: MGVPAGDVEKGKKLFVQRCAQCHTVEAGGKHKVGPNLHGLIGRKTGQAAGFAYTDANKAKGITWNEDTLFEYLENPKKYIPGTKMIFAGLKKPNERGDLIAYLKSATK
What is the function of this protein?
Electron carrier protein.  The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase.  Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
What are the official names of this protein?
Cytochrome c-2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane.
Protein: PSTB1_STRA1
Sequence: MTQPILQVSDLSVYYNKKKALKEVSMDFYPNEITALIGPSGSGKSTLLRAINRMGDLNPEVTLTGAVMYNGHNVYSPRTDTVELRKEIGMVFQQPNPFPMSVFENVVYGLRLKGIKDKATLDEAVETSLKGASIWDEVKDRLHDSALGLSGGQQQRVCIARTLATKPKIILLDEPTSALDPISAGKIEETLHGLKDQYTMLLVTRSMQQASRISDRTGFFLDGNLIEYGNTKEMFMNPKHKETEDYITGKFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB 1, ABC phosphate transporter 1, Phosphate-transporting ATPase 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: LPXC_XANCP
Sequence: MTQQRTLKNTIRATGVGLHSGDKVYMTLRPAPVDHGIVFRRVDLEPVVEVPADAELVTETTLCTGLTCNGAKIQTVEHLMSALAGLGVDNVIVELSSAELPIMDGSSGPFVFLLQSAGIVEQNKAKRFIRIKQPVEVREGDKVARFEPYEGYKLGFTIEFNHPMIPAKQSRQEIEFSTSAYVKEISRARTFGFMRDLEYMRERNLGLGGSMDNAIVLDEFRVLNEDGLRYTNEFVRHKILDAIGDLYLAGGAILGAYEGFKSGHALNNKLVRALLADQAAWEWVSFPEGTEQPPVTYASPVYA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: SSL10_STAA8
Sequence: MKFTALAKATLALGILTTGTLTTEVHSGHAKQNQKSVNKHDKEALYRYYTGKTMEMKNISALKHGKNNLRFKFRGIKIQVLLPGNDKSKFQQRSYEGLDVFFVQEKRDKHDIFYTVGGVIQNNKTSGVVSAPILNISKEKGEDAFVKGYPYYIKKEKITLKELDYKLRKHLIEKYGLYKTISKDGRVKISLKDGSFYNLDLRSKLKFKYMGEVIESKQIKDIEVNLK
What is the function of this protein?
Plays a role in the inhibition of host complement activation via the classical pathway by interacting with the Fc region of human IgG and thereby interfering with the IgG/C1q interaction (PubMed:19913916).  Inhibits also the penultimate step of plasma clotting by interacting with prothrombin/F2 and coagulation factor X/F12.  Does not affect the protease activity of thrombin but interferes with the conversion of prothrombin to thrombin (PubMed:23754290, PubMed:28193526).  Interacts with human receptor CXCR4 and specifically inhibits CXCL12-induced calcium mobilization and cell migration (PubMed:19308288).
What are the official names of this protein?
Staphylococcal superantigen-like 10.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal/streptococcal toxin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CYMEH_MELDN
Sequence: GIPICGETCFFGKCNTPKCTCNKPLCYKN
What is the function of this protein?
Probably participates in a plant defense mechanism.
What are the official names of this protein?
Cyclotide mden-H.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family.
Protein: SODC_PANTR
Sequence: MATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTSAGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVVHEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn].
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ATPA_STRZP
Sequence: MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGLENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGESLIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIGRGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGALDYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLLLRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNVISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYRELEAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPVDDIVRFEEEFHTFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.