PharMolix/UniProtQA huggingface dataset:
Protein: OLA1_YEAST
Sequence: MPPKKQVEEKKVLLGRPGNNLKAGIVGLANVGKSTFFQAITRCPLGNPANYPFATIDPEEARVIVPSPRFDKLCEIYKKTASEVPAHLTVYDIAGLTKGASAGEGLGNAFLSHIRSVDSIYQVVRCFDDAEIIHVEGDVDPVRDLEIINQELRLKDIEFAQKALEGAEKIAKRGGQSLEVKQKKEEMDLITKIIKLLESGQRVANHSWTSKEVEIINSMFLLTAKPCIYLINLSERDYIRKKNKHLLRIKEWVDKYSPGDLIIPFSVSLEERLSHMSPEDAEEELKKLQTISALPKIITTMRQKLDLISFFTCGPDEVREWTIRRGTKAPQAAGVIHNDLMNTFILAQVMKCEDVFEYKDDSAIKAAGKLMQKGKDYVVEDGDIIYFRAGAGKN
What is the function of this protein?
Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency.  Has lower affinity for GTP.
What are the official names of this protein?
Obg-like ATPase 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_AGRVS
Sequence: MAPRGSQRTVNKIVAENRKARFNYEIIDTYEAGIMLTGTEVKSLREGKANIAESYASDEGEEIWLINSHLPEYLQANRFNHEPRRRRKLLLNKREINRLRVAINREGMTLVPLKIYFNEKGRAKLELALAKGKKLHDKRETEKERDWNRQKSRLLKTG
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: SYK_STRPQ
Sequence: MSNQHIEELNDQQIVRREKMMALAEQGIDPFGKRFGRTANSAELKENYADKTKEELHELNETAIVAGRLMTKRGKGKVGFAHLQDREGQIQLYVRKDSVGEDNYEIFKKADLGDFIGVEGEVMRTDMGELSIKATKLTHLSKSLRPLPEKFHGLTDIETIYRKRHLDLISNRESFDRFVTRSKMISEIRRYLDGLDFLEVETPVLHNEAGGAAARPFVTHHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQAYADYLDIMNLTEGIIQHAAKAVKGDGPIDYQGTEIRINEPFKRVHMVDAIKEVTGVDFWPEMTVEEAIALAKEKQVPLEKHFTSVGHIINAFFEEFVEETLVQPTFVFGHPVEVSPLAKKNPEDTRFTDRFELFIMTKEYANAFTELNDPIDQLSRFEAQAQAKELGDDEATGIDYDFVEALEYGMPPTGGLGIGIDRLCMLLTNTTTIRDVLLFPTMKP
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSB2_PYRAE
Sequence: MGEEVQIGATAVGIKAKDGVVLAAEKRVSYGFYTLSSAGKKVFVIDDKLAIASAGIIADMQTLAKILKLNAKAYELEMKRKPSTHSMARLLSVIMFSRRFMPFFAEVLVGGIDEEGPHLIVMDPLGSLIEDNYAALGTGAKLAVAVLDTGYRPDITVEEAKKLAVQALKAAIERDPVSGGGIDLAIVDKNGAREEEVRVQLLI
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta 2, 20S proteasome beta subunit 2, Proteasome core protein PsmB 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_GEOUR
Sequence: MDKQAAERRIQELHKEINRHNYLYYVEDRPEINDAEYDLLLRELQQLEKAYPDLVTADSPTQRVGAAPLEKFSQVTHRMPMLSLENAFNEEEMHDFDERIKRFLGLAAGDEIEYVCEPKMDGLAVELVYENGDFTVGSTRGDGYVGEDVTQNLRTVKTIPLSLAIATPPRLFEVRGEVYLGLAPFQKLNVEREEAGDPPFANPRNAAAGSLRQLDSRITARRPLSIFCYAAGSLEGHEFTSQSDLLNTIPGWGLPVNPLIRKVSGIGGVLAYYHEMSEKRESLPYEIDGVVVKVDSFDLQRELGEKTRSPRWAIAWKFPPRQAVTVVEEIVPQVGRTGVITPVAHLRPVEVSGVMVSRATLHNWEEMEKKDIRKGDTVVVERAGDVIPAVVKVITEKRKGDEQPLPIPANCPECGSEVVKIPGEVAVRCLGLSCPAQIRETIIHFASRHAMDIDGMGDKYIEQLLKLGLVKNVADLYYLKKDDFMRFERMGDKLAENLLGAIETSKQRELSRFIYALGIRHVGEHTAKLLANAFGSMENLEHASEEELLSIREVGPQVAQSIRTFFHNRNNIEVIDRMFNAGVKPSVEEKRVGGRFTGKTFVFTGALTRFTRDDAKRMVENEGGHAAGSVSKKTDFVVAGAEAGSKLDKARQLGVKVLTEDEFLAMLGVCRT
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: RPOC_CERS1
Sequence: MNQELSTNPFNPVAPVKTFDEIKISLASPERILSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMKYRGVVCEKCGVEVTLQKVRRERMGHIELAAPVAHIWFLKSLPSRIGLMLDMTLRDLERILYFENYVVIEPGLTDLTYGQLMTEEEFLDAQDQYGADAFTANIGAEAIREMLSAIDLEQTAETLREELKEATGELKPKKIIKRLKIVESFLESGNRPEWMILTVLPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPDIIVRNEKRMLQEAVDALFDNGRRGRVITGTNKRPLKSLSDMLKGKQGRFRQNLLGKRVDFSGRSVIVTGPELKLHQCGLPKKMALELFKPFIYSRLEAKGLSSTVKQAKKLVEKERPEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCSAFNADFDGDQMAVHVPLSLEAQLEARVLMMSTNNVLSPANGAPIIVPSQDMVLGLYYTTMERRGMKGEGMAFSSVEEVEHALAAGEVHLHATITARIKQIDEEGNEVVKRYQTTPGRLRLGNLLPLNAKAPFELVNRLLRKKDVQNVIDTVYRYCGQKESVIFCDQIMGMGFREAFKAGISFGKDDMLIPDTKWPIVNEVRDQVKEFEQQYMDGLITQGEKYNKVVDAWSKCSDKVAGEMMAEISAVRYDDAGAEKEPNSVYMMSHSGARGSPAQMKQLGGMRGLMAKPNGEIIETPIISNFKEGLTVLEYFNSTHGARKGLADTALKTANSGYLTRRLVDVAQDCIVRTHDCGTENAITASAAVNEGEVVSPLAERVLGRVAAEDILVPGSDEVIVARGELIDERRADLVDQANVASVRIRSPLTCEAEEGVCAMCYGRDLARGTLVNIGEAVGIIAAQSIGEPGTQLTMRTFHIGGIAQGGQQSFLEASQEGRIEFRNPNLLENANGEQIVMGRNMQLAIIDEAGQERATHKLTYGAKVHVKDGQTVKRATRLFEWDPYTLPIIAEKAGVARFVDLVSGISVREDTDEATGMTQKIVSDWRSTPKGGDLKPEIIIMNPETGDPMRNEAGNPISYPMSVEAILSVEDGQTVRAGDVVARIPREGARTKDITGGLPRVAELFEARRPKDHAIIAENDGYVRFGKDYKNKRRITIEPVDDTLNSVEYMVPKGKHIPVQEGDFVQKGDYIMDGNPAPHDILRILGVEALANYMIDEVQEVYRLQGVKINDKHIEVIVRQMLQKYEILDSGETTLLKGEHVDKAELDEVNQKAMDHGMRPAHAEPILLGITKASLQTRSFISAASFQETTRVLTEASVQGKRDKLVGLKENVIVGRLIPAGTGGATSRVKKIAHDRDQKVIDTRRAEAESAAALAAPTDEVIDLGSEDSGLVETVENREE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: AMY_NIACI
Sequence: MNKKWLNIPALIALLAAIAFGSVAPAEAAPATSVSNKQNFSTDVIYQIVTDRFVDGNTANNPAGSAYDATCSTNLKLYCGGDWQGIMNKINDGYFTGMGITALWISQPVENIYSVINYSGVNNTAYHGYWARDFKKTNPAFGSMTDFANLISAAHSRNIKVVIDFAPNHTSPAMETNASFGENGKLYDNGTLLGGYTGDTNGYFHHNGGTDFSTLKNGIYKNLYDLADLNHNNSTIDTYFKNAIRLWLDMGIDGIRVDAVKHMPFGWQKNWMSSIYSYKPVFTFGEWFLGTNETDANNTYFANESGMSLLDFRFSQKVRQVFRDGSDTMYGLDSMLSSTAADYYSVNDQVTFLDNHDMDRFQVSGANGRKLEQALALTLTSRGVPAIYYGTEQYMTGNGDPNNRAKMSSFSTSTTAYNVISKLAPLRKSNPAIAYGTTQQRWINNDVYIYERKFGNNVAVVAINKNLTSSYSIAGLNTSLPSGTYTDVLANSLSGNSITVGSSGAVNTFTLQAGGEASGLTRRRQRLR
What are the official names of this protein?
Alpha-amylase, 1,4-alpha-D-glucan glucanohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: SRP54_MACFA
Sequence: MVLADLGRKITSALRSLSNATIINEEVLNAMLKEVCTALLEADVNIKLVKQLRENVKSAIDLEEMASGLNKRKMIQHAVFKELVKLVDPGVKAWTPTKGKQNVIMFVGLQGSGKTTTCSKLAYYYQRKGWKTCLICADTFRAGAFDQLKQNATKARIPFYGSYTEMDPVIIASEGVEKFKNENFEIIIVDTSGRHKQEDSLFEEMLQVANAIQPDNIVYVMDASIGQACEAQAKAFKDKVDVASVIVTKLDGHAKGGGALSAVAATKSPIIFIGTGEHIDDFEPFKTQPFISKLLGMGDIEGLIDKVNELKLDDNEALIEKLKHGQFTLRDMYEQFQNIMKMGPFSQILGMIPGFGTDFMSKGNEQESMARLKKLMTIMDSMNDQELDSTDGAKVFSKQPGRIQRVARGSGVSTRDVQELLTQYTKFAQMVKKMGGIKGLFKGGDMSKNVSQSQMAKLNQQMAKMMDPRVLHHMGGMAGLQSMMRQFQQGAAGNMKGMMGFNNM
What is the function of this protein?
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (By similarity).  As part of the SRP complex, associates with the SRP receptor (SR) component SRPRA to target secretory proteins to the endoplasmic reticulum membrane (By similarity).  Binds to the signal sequence of presecretory proteins when they emerge from the ribosomes (By similarity).  Displays basal GTPase activity, and stimulates reciprocal GTPase activation of the SR subunit SRPRA (By similarity).  Forms a guanosine 5'-triphosphate (GTP)-dependent complex with the SR subunit SRPRA (By similarity).  SR compaction and GTPase mediated rearrangement of SR drive SRP-mediated cotranslational protein translocation into the ER (By similarity).  Requires the presence of SRP9/SRP14 and/or SRP19 to stably interact with RNA (By similarity).  Plays a role in proliferation and differentiation of granulocytic cells, neutrophils migration capacity and exocrine pancreas development (By similarity).
What are the official names of this protein?
Signal recognition particle subunit SRP54, Signal recognition particle 54 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. SRP54 subfamily.
What are the subcellular locations of this protein?
Nucleus speckle. Cytoplasm. Endoplasmic reticulum.
Protein: MND1_DANRE
Sequence: MSKKKGLSLEEKRSRMMEIFFETKDVFQLKDIEKIAPKSKGITPMSVKEVLQSLVDDNMVDTERVGTSNYYWAFPSKALHARKRRLEELEKQLEDGSQRKKALQQAVDKAKVGREVNEEREDLLKELTALKGQRDQMKVEIEKYQECDPAVVEEIRNANIAAKEAVARWTGGTFGNYLISYLLTCSLTRQEPWAHHLSPSSGFSPGTACQTCYYYQQAIS
What is the function of this protein?
Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis.  Stimulates both DMC1- and RAD51-mediated homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks (By similarity).
What are the official names of this protein?
Meiotic nuclear division protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the MND1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PYRE_BORBR
Sequence: MSASASTAADFVRFALDEGVLRFGSFKVKSGRISPYFFNAGLFNSGRSVGALAGFYAQALVDSGVAFDMLFGPAYKGIPLATATSVALAGHRAMAGRDVPFAFNRKEAKDHGEGGTLVGAPLTGKVVIIDDVITAGTSVRESVEIIRAAGAEPAAVLIALDRMERAGPDDALSPHSAVQDVARTYGIPVVSIASLADIMTLLQDDAQFAEHREAVQAYRSKYGV
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: YOA5_SCHPO
Sequence: MDLWKKGKRFFRFSKEPVITCINTSYAGKEIIFDLIANPQMETKDVNLTLDFDAPIFHRKAGIDGLLTLTNKSKVNEIQLISIEVFIIGICKHKFHSSTVFLCLGTHIMEGQYIVPEELLDYAKKRGKNRIISIPNHSTVDIPFQVNFPKHVEVGPGRQIHSRVKVQYFAYANIIYQSADKLRSRRECQEINVLPSISPSSFLDSPSIMCVSKQPDLKKDRQRKSATRITVSLPRTDWLAGESVVSKIKIENHSKSSIKTLKLCLYRRIIGFDPPSWKTQQMMSHLNLSRKNSEVSKTCKCLQKETIRCNKKSNCYNWNGIAALETYTTECHIQIPDKEATITVGSNFEVDHFLKISVGNKLWTLNRVEIPFKIISANSLSLEQENVFLNLEKLTNKASPHGLPISVRLGNSLSYDALSAARRMRNTRYFLYS
What are the official names of this protein?
Uncharacterized protein C557.05.
What is the protein family that this protein belongs to?
Belongs to the arrestin family.
Protein: MIAB_TRIL1
Sequence: MNHKKLYIDTVGCQMNVNDSERIVTMLQPLGYTQTSRRHEAALILFNTCTVRAGAEECLLQNIANLKNLKRKKPGTLIGVAGCVAQQMGAELLQKFPWVDLVFGTHNLHLVPEMVKDAEAGRRRAETDFLDSSERLDLFPPIEGRKRVSAFVTVMQGCDNFCSYCIVPYVRGREISRRFAEILQEVQDLAAQGLREVVLLGQNVNSYGLKGEEQPSFAELVRAVAAVSGIDRVRFVTSHPKDMSDDLIACFADLAKLCGSLHLPAQAGNNRILKAMNRGYSREHYLETIYKLRQARPEIKITGDMIVGFPGETEAEFEETLSLMEEVRYFDLFSFVYSPRPGTKAAELSDELAKEVKLARLDRLQKLQAVHSRIHNETYVGSTQQVLVEGLAKRHGQVSGRCDSGRIVNLAGSPALIGKLVDVKILEGYANSLLGELL
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COFI_YEAST
Sequence: MSRSGVAVADESLTAFNDLKLGKKYKFILFGLNDAKTEIVVKETSTDPSYDAFLEKLPENDCLYAIYDFEYEINGNEGKRSKIVFFTWSPDTAPVRSKMVYASSKDALRRALNGVSTDVQGTDFSEVSYDSVLERVSRGAGSH
What is the function of this protein?
Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner.  It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin.  Binding to F-actin is regulated by tropomyosin.  It is the major component of intranuclear and cytoplasmic actin rods.  Required for accumulation of actin at the cell division site via depolymerizing actin at the cell ends.  In association with myosin II has a role in the assembly of the contractile ring via severing actin filaments.  Involved in the maintenance of the contractile ring once formed.  In association with profilin and capping protein, has a role in the mitotic reorganization of the actin cytoskeleton.  In effect, yeast cofilin increases the rate of actin polymerization by making new ends available for actin subunit addition.  Such a protein complex is important for the polarized growth of yeast cells.
What are the official names of this protein?
Cofilin, Actin-depolymerizing factor 1.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Nucleus matrix. Note=Throughout the cytoplasm (but not on the cytoplasmic cables) and major component of the cortical actin cytoskeleton.
Protein: NTPPB_THIDA
Sequence: MTRTSPTLVLASTSRYRRELLARLRLPFEVLAPNVDETPLPGETRSATALRLSVLKAQAAAMTHRDALVIGSDQVLMLGTEQLGKPGDHERAFAQLKKMQGRAMVFHTALTLLNSRTGSVQTRDVPTVVHIRPLTDAQIEAYLKKEQPYDCAGSAKSEALGIALMERMESPDPTALIGLPLMALTEMLAQEGVDVLTWPAT
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP).  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
7-methyl-GTP pyrophosphatase, m(7)GTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YceF subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEMR_ECOL6
Sequence: MNKHTEHDTREHLLATGEQLCLQRGFTGMGLSELLKTAEVPKGSFYHYFRSKEAFGVAMLERHYAAYHQRLTELLQSGEGNYRDRILAYYQQTLNQFCQHGTISGCLTVKLSAEVCDLSEDMRSAMDKGARGVIALLSQALENGRENHCLTFCGEPLQQAQVLYALWLGANLQAKISRSFEPLENALAHVKNIIATPAV
What is the function of this protein?
Involved in response to both electrophiles and reactive chlorine species (RCS).  Represses the transcription of the nemRA-gloA operon by binding to the NemR box.
What are the official names of this protein?
HTH-type transcriptional repressor NemR.
Protein: TRPD_LEPBJ
Sequence: MEPRAIVLKLIEHKHISVEEAEFFMNRVMKGEVSEILLSSFVTAMRAKGESVDEVLGCTLALRKNALKPKTVFPFDLLDTCGTGGDGQGTINVSTLSAITLASLGVKVAKHGNRSVSSHTGSSDILARLGYQTEATQEEVEAHLISRGFTFLFAPMWHPSMKYAGSVRKELGFRTVFNMIGPLSNPFSPQFQIIGVYQPELTELFIKVLQYLGLKRALVCHSRDGLDEFSIFQTTDYTLLENEVISRHSFDPRTLGFSSLKREEVYADSSEHAEVLARRVLNSEPIAGTHAVALNAGAGLFVMGKVKTIEQGYKIAWEALLSGKTRKYFEDLISKE
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: POLR_NORAV
Sequence: MLIEAFINSLLQNLGIMMSFRDLVASPWILLVIAIPLCAFASSASMVREMLFRHKITENILKGTGVEELFNPFGIIIKYFLYFAILYAFIKYIRNNINVITEKVNFIRRVVSNPTGTTGRRGVLGRCVEQIVEYPTFFITMVYELQQIKNKKDLISKITMISSILKLPLGIWESTVGRMLDRPAIEGTEEMLEDVLPIVAMGLTITKTQIGDVPVESFLVNLDRNQKACENIIKRMQPLMIKMGMMKDSSYDTILQVAKEVNELSEAETWMKTTLKLNPNEFLQTQGAVRVGEIREKVATLRNKLNTLQTKELRSDKVVTECQKHLASLEVLLIEVKVLENSNQTRVKPVGVTIQGEKQIGKTNLVAILSRKICEYVQEHGDISFRNATKWTTWSRQCRDEFDTGYTGQEITYVDDAFQQKDNKDHLMWFTFISNTAVGTNQADLKQKGLPYRSKLVFTTCNKSPDKSVTIEDIEALHARFPHTICLRRNKNKMPKRGAIDESYDWVDFYYGPMSKAVSAIGSNTTSTLKTMSLSEIVKIIGDDLIIQNNFYNSTIKDVGITGQEQMDGAQLERRQRMRELRDHLLRIRSGDENMPFLDETFELNSRPIQTDEKFIPLKDNLDEEVMYGGISDQLLTRFDNIIERSLEGYDVESRELGVEPLTTLNHVRSNMLSYRAWNLINSMCINKTETFSAWLGRYITECVEGVAENLVTTKVKIRINPFTGLQLIAAKRMLQENKLIDMDEIPSTSANSYETVYDQIKNFVNDELSLMETDVVDLALAKISLSQIRSNIKRSTWLDVNDWILALKHKISGKSFAKHMDLYPSSLDSFLLTLKDWEVEDRIKFNSIYKQKVLFVQSRFSLYCWSPFISRGTRFVKVTSRFRELVDKLETGILFHEIKSVTNGIRWLGGAGNNGHVGERVRVIAHTAQFPKKSYPQNGFPINEELHREWIQLVINSDYKYHSLIGEEKVNILWNLIRLQPQREVENFKVYLEDLQASPPKTGTICAKVVNDIKAEVTSSYRQFNNYYTRLTKDGMHTLLSMLSRIGVPISDYWNDLLVDKAPAITAVTVGAITSLAIITIVKTFQYAIAGEEQSKGEKRAKQKNIATTKLQKLKFTLGKEQAEGDSIEHVKEFDGDVKFETIEKLFDHIDEHPNLNIVGLNLVAPENPIAIYAAREESYDFSFSEPRPPQWKKVVTFKEDSKRIISLQLRGEDTEDNILDEIEHAIKVSHGMPYAEWIFNGWFKKESNDNILYCVELDLVTAKTQSGPVGWTRAQTKNLKDLEIQLNKGKPIDVKSVVLGAPQASTQATDTMDVLVNKHLVKVHCLSYENLNNLALNGTQVFALASDNILIVPAHAARQNKWIRFSRATQTGHYGVAKVDERRIDFTRDIAIAIILTRAEAEQKLCELGYSIQLTNISKEKFHFPLITKYLLTADQSEVEWMNCTTLHYFAKNKTVGLGRTTSFQVSEFLCGNEYISKKLVACAQGLQSSVELSRLGDCGSPIVLASGKKAGKLIGFHGYHSPNLQTWYGAMLTVEDLGIINGVEEHFDDPWAKLITQGLPVDLPIGPEVEYVGNLIRPSLPVTNDSLDHWHKSPFADQFEEQLAPGRLNPYDSYIEGDLPTNLEGRKSLILGPNSEMAKTLPELDQGILDWIVDQLVVEQVATFKAENLLTKVSDDIDEMLDYALNGNVDNTYVRGMEVNKASGLPWSLSGSPKKSDFIDVDEATGVRSFKVNANGDALKNRVILKLQQAKMGNRILSFSSSKLKDQPIKIAQAKSGRTRVFHCIPVDLILFSGALYGPYKEAYTKAGLKCYHAVGIDPKSVGWQQLATYMTKHPNYFDADYKNYDKYLHRQVFKAVRKIQRSVIQQVCPDKWDKARAVEELDAIDTYVVDYQTVYKTNRGNKSGSYTTTIDNCLANDIYGLYAWVKTTGLRSLWDYRQNVSSVAFGDDIIKSVSDEYKDKYNYCTYRDVLNATGHIMTPGSKDGEEKPFTSFENLQFLKRGFKLENGMVLAPLLQRSIEGPFVWTDIREDQITVWVNLVQEQLIEAALWGEEYYNELCQKLKCGTNRTLNGALAVLLNTSWEVTFQKFCNRYYGIKRGDL
What is the function of this protein?
The peptidase activity is involved in polyprotein maturation, possibly along with hosts proteases.  Transmembrane protein may be surface viral glycoprotein.  RNA-directed RNA polymerase replicates the viral genome (Probable).
What are the official names of this protein?
Replication polyprotein.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: KTXA_KLULA
Sequence: MNIFYIFLFLLSFVQGLEHTHRRGSLVKRAVCYDTDQVPLNIFFGYNRADKTDSNKNMALNIFNVFRGFLAGEGGESFYNSNGNVYGFMWVGSMVHNRGFKDNILPIMENEVKNYGIPKTLYLEYDGGGDPMKSFGIILDTTSRDTVVKAAKLWSQGKKLNSYEGSKNYQATACYLSYAYRKPIVNDNFVGTCDYFTLESGKTPADQSGINGESLQGYNPNLDFSKLSAGQPICKTIGNPPNFKPSKNSDGSCKTYKVSSGESCSSIAVKYYPLSLNDIENYNKGNYGWKGCSSLQKDYNLCVSDGSAPRPVSNPIAECGPLAPGEKYNAKCPLNACCSEFGFCGLTKDYCDKKSSTTGAPGTDGCFSNCGYGSTSNVKSSTFKKIAYWLDAKDKLAMDPKNIPNGPYDILHYAFVNINSDFSIDDSAFSKSAFLKVTSSKKIPSFGGWDFSTSPSTYTIFRNAVKTDQNRNTFANNLINFMNKYNLDGIDLDWEYPGAPDIPDIPADDSSSGSNYLTFLKLLKGKMPSGKTLSIAIPSSYWYLKNFPISDIQNTVDYMVYMTYDIHGIWEYGKANSYINCHTPRKEIEDAIKMLDKAGVKFNKVFGGVANYGRSYKMVNTNCYNYGCGFQREGGNSRDMTNTPGVLSDSEIIDIDSSDKKNDRWVDTNTDCIFMKYDGNSVVSWPKSRYDLEDMFKNYGFAGTSLWAANYFKHDEWKNDEDDNNDDTEDPFDEENVYFDVYDCKNKAGYDLDNPVYGCRLETAINIIIWNGTESVNTVLNILNDYDNYIKYYEALTRAHYDSVMEKYEKWLFEEDGYYTYYTDVDGDDIIITPPDKKKRDYIQEKYSFEKEFMMSQNMTELTEIKVNKTINFMLNGTSLAVKEYNNEKVLYKRGDIPPPGSNNRLIRNSIILDKDKEAAIASFKQYSGIELSKDSFVQRDKDKKFDLNGKHYTFMHSTILNAIVLFPNVLTNIDSDYIHHISDLIEQAHNSLGNESPDNIYEVLESVVVFMSVSEIADYTYTEGKKIKEKYDKMKKTMIVGIILGIIGGLSLFLGPIGIATSVLADFALLGADAAINGELNPSDLAFALAGLFLPVFASLGKTFKFAEALQKININKSKNFDNLNEFEKIRFFRSKLGKVKMCGS
What is the function of this protein?
The alpha subunit is a potent exochitinase.  Along with the beta subunit it plays a role in the initial interaction of the toxin with sensitive cells and allow the gamma subunit (the active toxin) to gain entry into the cell.
What are the official names of this protein?
Killer toxin subunits alpha/beta, RF2 protein.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family.
Protein: GATA_ANAD2
Sequence: MSTPAHELCRLGLREAGAGVAAKAISSSELVEASLARIQATDGKLGAFLAVSADRARAAARAADARAARGERRSELDGVPVAVKDLFVTKGVPTTAGSRILEGWLPPYDATVVERLEAAGAVIVGKLNMDEFAMGSSNENSAYKPCHNPWDLSRTPGGSSGGSAASVAAGQVHASLGTDTGGSIREPAAFCGVVGVKPTYGRVSRYGVVAFASSLDQVGPLAREVGDAALVLRTIAGHDPRDMTSSTRPVDDYLAPLEDGARGLRVGVPREWLSGGLDAGVEAAVRAALDTYRRLGATLVDVSLPHSKYGIGAYYLIAPAEASSNLARYDGVRFGLRAADAKGLKEMYAESRERGLGAEPKRRIMLGTYALSSGYYDAYYLRAQKVRTLIRRDFDEAFRGCDVIAGPVTPSVAFKLGERTGDPLRMYLADIFTITCNLAALPGLSVPCGLEAASGLPVGLQLVGRPFDEATLFRAARALERELGPLPAPPEP
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: RS14_CHLCV
Sequence: MAKKSAVARENKRRRLVEANYKKRSELRNIAKSLTASEEEKENARVALNKMRRDTAHIRLHNRCLLTGRPRGYLRKFAISRICFREMASMGEIPGVIKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: IXTPA_DESPS
Sequence: MIPMIVLATTNQNKVKEFQEILKDFAIEIRSLAEFGPIPEAIEDGKDFDENAYKKAIHTAKILGIPAIADDSGLEVHALNGAPGVYSARYSGEGATDASNCDKLLEELAGKEDRSANFTCVISIATPGGPALTYEGRCDGKILTEKRGKSGFGYDPLFYFAEYDKTFAELSMEEKNRVSHRGKALAEIKAEAPQIIKWLEQRLSEEKPAKPDHSEFEGNDWSK
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: NADE_LACLA
Sequence: MTLQDEIIKELGVKPVIDPKEEIRVSVDFLKDYLKKYPFIKSFVLGISGGQDSSLAGRLAQIAIEEMRQETADETYKFVAIRLPYGVQADEEDAQRALAFIQPDVSLTVNIKAAVEGQVAALNEAGIEVSDFNKGNIKARQRMITQYAVAGQYQGAVLGTDHAAENITGFFTKFGDGGADLLPLFRLNKRQGKALLAELGADPAIYEKVPTADLEEGKPGLADEIALGVTYNDIDDYTEGKVISEDAKAKIEAWWKKTQHKRHLPISVFDDFWK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: GCH1_VIBC1
Sequence: MSGLSESAKLVKEALEQRGLETPMRPNNVSREEKKEKIEHHMREILGLLQLDLTDDSLEETPHRIAKMYVDEIFSGLDYSNFPKITVIENKMNVSEMVRVKDITVTSTCEHHLVTIDGKAAVAYIPRGKIIGLSKINRIVRFFAQRPQVQERMTQQILVALQTLLESDDVAVTIDATHYCVKSRGVMDATSETTTTALGGIFKSNPATRAEFLHGLR
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.