PharMolix/UniProtQA huggingface dataset:
Protein: E4PD_ALIFM
Sequence: MLRVAINGFGRIGRSVLRALYESDKRDKIEVVAVNELSQPEAMAHLFQYDSTHGRFQHKVTHDQEYLYIDLPNGSQDKVRILHQADLSLLPWQSLEVDLILDCTGVYGSKADGEKHINAGAKKVLFSHPGGSDLDNTIIYGVNHDTLLPEHRIVSNGSCTTNCIIPVIKAIDDAFGIDSGTITTIHSSMNDQQVIDAYHSDLRRTRAASQSIIPVDTKLHKGIERIFPKFSNKFEAISVRVPTVNVTAMDLSVTINTNVKVNDINQTIVNASRCTLHNIVDYTEAPLVSIDFNHDPHSAIVDGSQTRVSNGHLVKMLVWCDNEWGFANRMLDTALAMSK
What is the function of this protein?
Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
What are the official names of this protein?
D-erythrose-4-phosphate dehydrogenase, E4PDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BSP_BOSSE
Sequence: YSLQNDPEITLIDSTIEWDEGYDVTARFLDYLNSLDAGFVAELENKTVEQLWSEYKASYGPNGQ
What is the function of this protein?
Metalloprotease, digests gelatin and azocasein (in vitro).
What are the official names of this protein?
Basic secretory protease, Boswellia basic secretory protease, BBSP.
Protein: TRUA_BRUC2
Sequence: MPRYKLTVEYDGTPYVGWQRQENGHAVQGAIEQAFKKFCGEDLTLSAAGRTDAGVHATAQVAHVDLAKDWGAGKVRDAVNAHLVMADERISILNVEKTTDTFDARFSARARHYLYRIHNRRAPLAVDYQRAWWVQKQLDADAMHEAAQRLLGEHDFTTFRATQCQAKSPVKTLDRLDVTRNGDMVEMRVSARSFLHNQVRSFAGSLMEVGVGRWTADDLQAALEARDRKACGQVAPPYGLYLVGVDYAFPF
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: DSVC_DESVH
Sequence: MAEVTYKGKSFEVDEDGFLLRFDDWCPEWVEYVKESEGISDISPDHQKIIDFLQDYYKKNGIAPMVRILSKNTGFKLKEVYELFPSGPGKGACKMAGLPKPTGCV
What is the function of this protein?
Catalyzes the reduction of sulfite to sulfide.  This is the terminal oxidation reaction in sulfate respiration, a process catalyzed by the sulfate-reducing bacteria.
What are the official names of this protein?
Sulfite reductase, dissimilatory-type subunit gamma, Desulfoviridin subunit gamma, Hydrogensulfite reductase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the DsrC/TusE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STP8_ARATH
Sequence: MAVVISSNGNSKSFDAKMTVYVFICVIIAAVGGLIFGYDIGISGGVTAMDDFLKEFFPSVYERKKHAHENNYCKYDNQFLQLFTSSLYLAALVASFFASATCSKLGRRPTMQLASIFFLIGVGLAAGAVNIYMLIIGRILLGFGVGFGNQAVPLFLSEIAPARLRGGLNIVFQLMVTIGILIANIVNYFTSSIHPYGWRIALGGAGIPALILLFGSLLICETPTSLIERNKTKEGKETLKKIRGVEDVDEEYESIVHACDIARQVKDPYTKLMKPASRPPFVIGMLLQFFQQFTGINAIMFYAPVLFQTVGFGNDAALLSAVVTGTINVLSTFVGIFLVDKTGRRFLLLQSSVHMLICQLVIGIILAKDLDVTGTLARPQALVVVIFVCVYVMGFAWSWGPLGWLIPSETFPLETRTEGFALAVSCNMFFTFVIAQAFLSMLCAMKSGIFFFFSGWIVVMGLFALFFVPETKGVSIDDMRDSVWKLHWYWKRFMLEEDEHDVEKRTD
What is the function of this protein?
Mediates an active uptake of hexoses, probably by sugar/hydrogen symport.
What are the official names of this protein?
Sugar transport protein 8, Hexose transporter 8.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HSLO_THEP3
Sequence: MRDYIVRATAYNNKILAIAAFSTQTAQKAKEIHNLTPTTCAALGRALTAVAMMRVMMKGEKDKVTLVIKGDGPIGNIVVVSNYPGIVKGYVGNPTVDLPLSEKGKLDVGKAVGKNGYVTVIKDIGLKEPYVGTVELQTGEIGEDIAYYFYTSEQVPSAVGVGVLVGKEGNVLASGGFIIQLLPNIEEEVVAKVEEALKNISSVTELLRKGYLPEDILNHILGEMGLNILERVDLKYECDCSQERFETAIIALGKEEIKKLIAEGQSVEAVCHFCGKKYLIEESRLKELLRIAEE
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_BUCA5
Sequence: MLKCIKHEYGIKNMKSIRNFSIIAHIDHGKSTLSDRLIQLCGGLSEREMSNQVLDSMDLEKERGITIKAQSVMIDYKNKSGNIFNLNFIDTPGHVDFSYEVSRSLAACEGALLVVDSTQGVEAQTLANCYTAIDMNVEIVPVLNKIDLPNSNADKVAKEIEDIIGIPALDAIRCSAKTGEGIEDLIERIINDIPYPKGSINSPLQALIIDSWFDNYLGVVSLIRIKNGILFEKDKIQVMSTGKNYYVDQIGVFTPKKLNKNQLRCGEVGWIICGIKNIIAAPVGDTLTTAKNPAKNMIIGFKKIKPQIYAGLFPLTSDQYEMFRDALGKLSLNDASLFYEPENSVALGFGFRCGFLGVLHMEIIQARLEREYSIDLITTIPTVIYEIELINGKIIYLDTPSNFPNMNDIKIIKEPIVECSILSPPQFLGSIIKLCIKKRGVQINMVYHSHQVLLKYNIPMNEVILNFFDELKSVSSGYASLEYDFKYFQSVKMVRIDILINSEKVDALTILSYHKNAQSRSREIVDKMKKLIPRHQFDISIQAVINNSVIARSTIKQLRKNVLSKCYGGDVSRKKKLLQKQKDGKKRMKKIGNVNVPKTVFLSILNSRES
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YWQM_BACSU
Sequence: MELKQLITFITAAEHVNFTLTAKMLNYAQSSVTSQIKSLEEEIGTPLFERLGKRLILTEAGKTFKSYAQKIIALTEEAKMATNQVRETTGTLKIGATESQCTYRLPPIIKEFKQAFPQVKLIFKPYISNEQAKEQLLQGQLDITFILDVNRMEDALHVESLIQDEIKMVAANDHPFPADLPVTLKDLQNETLLLTEDGCSYRTLFENNLHDSGIYPNKLEFVSIEAIKQCVMAGLGIGILPEMTVKDDIAAGRMKELNWQSDCPVFTQLAWHKDKWMSAPLKAFIDLTRKTFK
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator YwqM.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSD_ECOHS
Sequence: MLNSFKLSLQYILPKLWLTRLAGWGASKRAGWLTKLVIDLFVKYYKVDMKEAQKPDTASYRTFNEFFVRPLRDEVRPIDTDPNVLVMPADGVISQLGKIEENKILQAKGHNYSLEALLAGNYLMADLFRNGTFVTTYLSPRDYHRVHMPCNGILREMIYVPGDLFSVNHLTAQNVPNLFARNERVICLFDTEFGPMAQILVGATIVGSIETVWAGTITPPREGIIKRWTWPAGENDGSVALLKGQEMGRFKLGSTVINLFAPGKVNLVEQLESLSVTKIGQPLAVSTETFVTPDAEPAPLPAEEIEAEHDASPLVDDKKDQV
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL27_HELPJ
Sequence: MAHKKGQGSTQNNRDSAGRRLGVKKFGSEFVRAGNIIVRQRGTKIHPGNNVGMGKDHTLYALIDGVVKFEHKDRSRKKVSVISGNFGE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: ASSY_METHJ
Sequence: MGKGTVVLAYSGGLDTSICIPLLKEEYGYDRVVTVAADVGQRKEEISIAEEKGKRFADKHYTLDLIDQFVDRCLMPSIKANGLYEGYPMGTSLARPVIAEAVVEIAKKEDATAVAHGCTGKGNDQLRFDVVFRAADLEVIAPIRERNMTREWEIGYAEKHGIPVPVDKEKPWSVDENLWSRSIEGGKLEDPAFHPPEEIYAWTVSPLKAPDEPQVLSITFEAGIPVALDGKRMKGADLIRTVGQIAGGHGIGRNDMMENRVLGIKAREIYEHPAANVLLTAHADLERLVLTREEYAFKQSVDAKWAQLAYYGLIYEPLWDALNAFIDTTQKRVNGTVDVRLFKGSVTVLGRSSPDSFYSIDVASFDSTTIDQTDAIGYSMYYGLQARLVRKKQKK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_BRUO2
Sequence: MKFLDQAKIYIRSGNGGAGAVSFRREKFLEFGGPDGGDGGRGGDVWVEAVDGLNTLIDYRYQQHFKAKTGMHGMGRNMTGGKGDDVVLRVPVGTQIFEEDNETLICDITEVGQRYRLAKGGNGGFGNLHFTTSTNRAPRRANPGQEGIERTIWLRLKLIADAGLVGLPNAGKSTFLASVTAAKPKIADYPFTTLHPNLGVARIDGREFVIADIPGLIEGASEGVGLGDRFLGHVERTRVLLHLVSAQEEDVAKAYQVIRGELEAYEHGLADKPEIVALSQVDTLDPETRKAKVKALKKACGCEPLLLSAVSHEGLNDTLRQLARIIDLSRAEEAGTAQAEE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENTD1_HUMAN
Sequence: MAFRRQVKNFVKNYSDAEIKVREATSNDPWGPSSSLMLDISDLTFNTISLSEIMNMLWHRLNDHGKNWRHVYKSLTLMDYLIKNGSKKVIQHCREGFCNLQTLKDFQHIDEAGKDQGYYIREKSKQVITLLMDEPLLCKEREVACRTRQRTSHSILFSKRQLGSSNSLTACTSAPTPDISASEKKYKLPKFGRLHNKRNVCKAGLKQEHCQDVHLPTETMLSQETLPLKIHGWKSTEDLMTFLDDDPELPLLATPPSIVSPITCLSEAEEVCNLSGADAVPTLSENSPSGQRDVSLDKRSDGIFTNTVTENLLETPLEKQSAAEGLKTLTILPACWSSKEEFISPDLRVSKSDSTFHNQASVETLCLSPSFKIFDRVKEIVINKAYQKPAQSSIQMDDKILKTTTRVSTASEGASSFSPLSMSSPDLASPEKSAHLLSPILAGPSFWTLSHQQLSSTSFKDEDKTAKLHHSFASRGPVSSDVEENDSLNLLGILPNNSDSAKKNISHISSSHWGEFSTQNVDQFIPLSCSGFQSTKDFPQEPEAKNSISVLLREVKRAIARLHEDLSTVIQELNVINNILMSMSLNSSQISQSSQVPQSSEGSSDQI
What are the official names of this protein?
ENTH domain-containing protein 1, Epsin-2B.
Protein: GLMU_BUCAT
Sequence: MLTQEIIIVILAAGKGTRMKSNHPKVLHFLGGKTILEHVIETAQSIKPKKIILVYSDQKKPVLSNIYNIPIQWIIQKKPQGTGHAILLAIKKISDNTEILVLYGDVPFISPVSIKKLQKSKKQSKISLLTAKVKNPNGYGRILRKKGKVISIIEDQDASNEQKNIKEIYSGIFIAQSKDLTRWLKKIDKKNEKQEFYATDIIALAHLEGSFIKTIEPLNYEEILGINNKLQLSNLEKIFQKKQINKLLINGVTIKDPSHFIFRGTLQHGQNVEIDTGVILENNVILGDDVKIGPGCIIRNSSIDSNTNIQAYTIIENSKIGKGCIIGPFAHLRSNTLLDRNVHIGNFVETKDTFIKNESKVKHLSYLGNSEIGSKVNIGAGSITCNYDGANKFKTIIGDNVLVGSNTQLIAPIKIAKNTTIAAGTTVTKDVNTPCLVYNTKEQKYKKNWMRSKKIIKKN
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARAB_SALA4
Sequence: MAIAIGLDFGSDSVRALAVDCATGDEIATSVEWYPRWQEGRYCDGPNNQFRHHPRDYMESMEAALKAVLAQLSSAQRANVVGIGVDSTGSTPAPIDADGNVLALRPEFAENPNAMFVLWKDHTAVEEADEITRLCHKPGKVDYSRYIGGIYSSEWFWAKILHVTRQDSAVAQAAVSWIELCDWVPALLSGTTRPQDIRRGRCSAGHKTLWHESWGGLPPSSFFDELDPCINRHLRYPLFSETFTADLPVGTLCAEWAQRLGLPESVVISGGAFDCHMGAVGAGAQPNTLVKVIGTSTCDILIADKQSVGDRAVKGICGQVDGSVVPNFIGLEAGQSAFGDIYAWFSRVLSWPLEQLAAQHPELKTQINASQKQLLPALTDAWAKNPSLDHLPVVLDWFNGRRTPNANQRLKGVITDLNLATDAPALFGGLVASTAFGARAIQECFTDQGIAVNNVMALGGIARKNQVIMQVCCDVLNRPLQIVASDQCCALGAAIFAAVAAKIHADIPAAQQSMASAVERTLRPRPEQAQRLEQLYRRYQQWALSAEQHYLPTAAPAPTTPANQAILTH
What are the official names of this protein?
Ribulokinase.
What is the protein family that this protein belongs to?
Belongs to the ribulokinase family.
Protein: DIDA_AGKCO
Sequence: MIQVLLVTLCLAVFPYQGSSIILESGNVNDYEVVYPRKVTALPKGAIQPKNPCCDAATCKLTPGSQCAEGLCCDQCKFIKAGKICRRARGDNPDYRCTGQSGDCPRKHFYA
What is the function of this protein?
Inhibits fibrinogen interaction with platelets.  Acts by binding to alpha-IIb/beta-3 (ITGA2B/ITGB3) on the platelet surface and inhibits ADP-induced platelet aggregation in human platelet-rich plasma.
What are the official names of this protein?
Disintegrin acostatin-alpha.
What is the protein family that this protein belongs to?
Belongs to the disintegrin family. Dimeric disintegrin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPF_BURM9
Sequence: MNLNATLFAQMVVFLVLAWFTMKFVWPPLINALDERSKKIADGLAAAEKGKAELEAAHKRVDQELAQARNDGQQRIADAEKRALAVADEIKTNAQAEAARIIAQAKAEAEQQIVKARETLRGEVAALAVKGAEQILKREVDQTAHAELLNQLKAEL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PROB_THEP3
Sequence: MRIVVKVGTSTLTYENGKLNLEIMEKLVRQIANLLNRGEEVVLVTSGAIGAGMGKLNLKEKPKTIPEKQSLAAIGQGLLIEIYEKFFNEYGKITAQVLLTKEDFSDRRRYLNVSYTLSNLLKWGVVPIINENDTVTVDEIKIGDNDTLAALLASLVEADILIILTDIDGLYDKDPRIYKEAKIIEVVEEFSDELFKIAGSAGTKRGTGGMYTKIQAAKICWNSGVKMIIANGKIDNVLNQIANGEKIGTTFLPMKKPISSRKVWIAFNAKVSGRLFIDEGAAKAIIKHGKSLLPSGVVKTEGDYDVGDCVAVVDHQEKEIARGLINYSSEEVEKIKGCKTHEIEKILGYKYYDEVIHRDNLVILERGEKFGS
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DOXA2_HUMAN
Sequence: MTLWNGVLPFYPQPRHAAGFSVPLLIVILVFLALAASFLLILPGIRGHSRWFWLVRVLLSLFIGAEIVAVHFSAEWFVGTVNTNTSYKAFSAARVTARVRLLVGLEGINITLTGTPVHQLNETIDYNEQFTWRLKENYAAEYANALEKGLPDPVLYLAEKFTPSSPCGLYHQYHLAGHYASATLWVAFCFWLLSNVLLSTPAPLYGGLALLTTGAFALFGVFALASISSVPLCPLRLGSSALTTQYGAAFWVTLATGVLCLFLGGAVVSLQYVRPSALRTLLDQSAKDCSQERGGSPLILGDPLHKQAALPDLKCITTNL
What is the function of this protein?
Required for the maturation and the transport from the endoplasmic reticulum to the plasma membrane of functional DUOX2.  May play a role in thyroid hormone synthesis.
What are the official names of this protein?
Dual oxidase maturation factor 2, Dual oxidase activator 2.
What is the protein family that this protein belongs to?
Belongs to the DUOXA family.
Protein: VOSA_COCH5
Sequence: MAFTYNYSLQASYPSQRAYVPYQQAQVPTPSPIYSLPITNTTTAGALSPSSCFLSVRQQPKEALVTVKGKEKFRKPLDPPPMLELKVSSEIDPSQQFLQNPYLFVSVSLYKHDKDEAIEGTPFDILAGTLVSSLHRLKDVNNKDGAFFIFGDISIKVQGTYRLRFTLYELQPSYFTLSDLEQHKDLERYQGAALDPPEYGTYQCLGHVLSDKFNVVLPKDFKGLEESTYLSRAFSDQGVRLRLRKEARGMMSNKRSISGSGDLTTDQSQQQQQQQQPLAKKRREDSVESANPSSLMSGFYQNVSPFVNTPYLQTQGLQPQNLQNQGLQTPVRHDANYAWNLAYDPSFMGS
What is the function of this protein?
Component of the VEL2-VOS1 heterodimeric complex that plays a dual role in activating genes associated with spore maturation and repressing certain development-associated genes (By similarity).  The complex binds DNA through the DNA-binding domain of VOS1 that recognizes an 11-nucleotide consensus sequence 5'-CTGGCCGCGGC-3' consisting of two motifs in the promoters of key developmental regulatory genes (By similarity).  Required for normal pseudothecium development and regulates asexual spore compartmentalization, pigmentation and germination (PubMed:25080135).
What are the official names of this protein?
Spore development regulator vosA.
What is the protein family that this protein belongs to?
Belongs to the velvet family. VosA subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CSPL2_ARALL
Sequence: MRANNNNTREEERSSSSKQQQPQAHMSLKIIDSCLRLSVVPLSVATIWLTVTNHESNPDYGNLDYNSIMGLKYMVGVSAISAIYALLSTISLWVTCLVSKAWLFFVPDQVLAYVMTTSVAGATEIVYLLNKGDKIVTWSEMCSSYPHYCSKLTIALGLHVFVLFFFLFLSVISAYRAFSPFDPPCDSQTNIDA
What are the official names of this protein?
CASP-like protein 2D1, AlCASPL2D1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: INPD_EMENI
Sequence: MEKTQTPSLTPDELSARSSTPFEEREEEEEVHYVGHLKFSFIFVGLCLSVFQVALSLQDIGWYGSAYLFTDCAFQLVFGRLYSMLPVKIVYLGALLLFEIGSIICATAPNSIALILGRTIAGIGAGGILSGALTILSQSVPRAKVAVFNGILGAVNGIAFICGPLLAGGIINGTTWRWIFYINPIISAPTFFITVFLLKLDPPKTNVKTWRGRIAMLDLPAFTLFLGSILCLILALLWGGKEYSWKNARIIVLFILFGVIMLAFMLVQKRKGDDALVPMRILCQRSIAFGMFFSFCTSGTGFILEYYLPIWLQVIKDLSVISSAVKLLPIIAAAVVFTTLCGILTPVIGHYVPFMIIATMLLSVGMGLLSTLEYTSPIRHVLGFQVPAGVGLGCALQQTLVAAQTILPMNDIPIGVSLIVLAQTLGGTIALSAADTIYTGTLSSSISSRFPQINRETVLTTGNREIRNLVPAESLSVIMDLCNKAIVKTWYLSIGLAAASIIGVLGMEWRRVTPPKK
What is the function of this protein?
MFS efflux transporter; part of the inp gene cluster that mediates the biosynthesis of fellutamide B, a mycotoxin that acts as a proteasome inhibitor (PubMed:20952652, PubMed:27294372).  In the first step of fellutabmide B biosynthesis inpC activates 3-hydroxydodecanoic acid to generate 3-hydroxydodecanoyl-AMP that is then loaded onto the T0 domain of inpB (PubMed:27294372).  The 3-hydroxydodecanoyl-S-phosphopantetheinyl-T0 is sequentially extended with L-Asn and L-Gln by the two CAT modules of inpB (PubMed:27294372).  The linear lipodipeptide from inpB is then transferred onto inpA for the addition of the third amino acid, L-Leu (PubMed:27294372).  Reductive releasing of the lipotripeptide by the TE domain of inpA produces (2S)-fellutamide B (PubMed:27294372).  InpF might be involved in the release and transfer of the lipodipeptide from inpB to inpA (PubMed:27294372).  The inp cluster-encoded proteasome subunit inpE confers resistance to internally produced fellutamides (PubMed:27294372).  The MFS efflux transporter inpD may contribute to fellutamide resistance as well (PubMed:27294372).
What are the official names of this protein?
MFS efflux transporter inpD, Fellutamide B biosynthesis cluster protein D, Inp cluster protein D.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SMOC1_MOUSE
Sequence: MLPARVRLLTPHLLLVLVQLSPAGGHRTTGPRFLISDRDPPCNPHCPRTQPKPICASDGRSYESMCEYQRAKCRDPALAVVHRGRCKDAGQSKCRLERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTPVCSGPVTDKPLSQGNSGRKVSFRFFLTLNSDDGSKPTPTMETQPVFDGDEITAPTLWIKHLVIKDSKLNNTNVRNSEKVHSCDQERQSALEEARQNPREGIVIPECAPGGLYKPVQCHQSTGYCWCVLVDTGRPLPGTSTRYVMPSCESDARAKSVEADDPFKDRELPGCPEGKKMEFITSLLDALTTDMVQAINSAAPTGGGRFSEPDPSHTLEERVAHWYFSQLDSNSSDDINKREMKPFKRYVKKKAKPKKCARRFTDYCDLNKDKVISLPELKGCLGVSKEGGSLGSFPQGKRAGTNPFIGRLV
What is the function of this protein?
Probable regulator of osteoblast differentiation.  Plays essential roles in both eye and limb development.
What are the official names of this protein?
SPARC-related modular calcium-binding protein 1, SPARC-related gene protein, Secreted modular calcium-binding protein 1, SMOC-1.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix, basement membrane. Note=In or around the basement membrane.
Protein: RL15_MARN8
Sequence: MRLNELAPEPGSRPSAKRVGRGIGSGLGKTGGRGHKGLKSRSGGSVAPGFEGGQQPLARRLPKFGFTSRQQRYVAEIRLNELAKVEGDVVDLAALKKADIIREEIREAKVILSGELDRAVTVKGLRVTKGAREAITAAGGKVED
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: LPTD_BURMA
Sequence: MPPKTLFPLVPACDAAPRKKRLAVALLAVPGLVPAVSQAQLSGAAAEPQAFGSPWDLRLAPQLDEHPQKQGGKPATFVLADHTNGTAEQDLAAKGAAEIRRGNAAVKADAIHYDQDTDMADAYGKVTVANGGTTFSGPEAHLKVEANQGFMTTPKYRFTATGGTGSAERVQLLDSERSVFTNGTYTGCQCSTNPAWYIKGSEFDFDTGADEGVARNGVLFFQGVPLFGSPWLTFPLSGDRRSGFLPPTFSPFSSTNGFELSLPYYFNIAPNRDLTITPHIISKRGIFTQATFRYLSTNYSGTLTGEYLPDDRVAHRNRYAIFWQHQQNFGNGFGGYVYYNKVSDNLYPEELGSTNQFVNGVQTVYQQEAGLTYNNGPWSVLGRYQHWQTLPPSAAPYGREPQLNVKYTKYNVGGFDFGAEADYSRFRITTADQPEGDRVMFNPYVSYGLYGPGYFFVPKAQLHMASYDLTTTTGGVPGQPKRFTYSIPTLSLDTGLVFDRSVRLFGQDFIQTLEPRLFYVYTPYRNQSNAPLFDTAVSDFGLAEIFTPNTFVGNDRIADANRLTAALTTRFINPTTGDERARFVIAQQYYFTDQRVTLLPTEAPATARHSDLILGASVKLGAGFASETAFQYNVDNNQLVKSSVGFGYSPGERRVINVGYRYTRQNPTLSNEPINQILMSAQWPLTRRLYAVGRLNYDLASSRVVDGLVGFQYDADCWAFGVGVQRYANGLNSSGQQNSSTRVLAQLVLKGLTSIDNGLVTAFRAGVQGYTPLPPAPAPLSRFSNYD
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: ZAPD_SALTY
Sequence: MHTQVLFEHPLNEKMRTWLRIEFLIQQLSINLPIADHAGALHFFRNISDLLDVFERGEVRTELLKELERQQRKLQAWVEVPGVDQDRIEALRQQLKSAGSVLISAPRIGQQLREDRLIALVRQRLSIPGGCCSFDLPTLHIWLHLQQAQRDAQIESWLASLNPLTQALTLVLDLIRNSAPFRKQTSLNGFYQDNGDDADLLRLMLTLDSQLYPQISGHKSRFAIRFMPLDSENGLVPERLDFELACC
What is the function of this protein?
Cell division factor that enhances FtsZ-ring assembly.  Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
What are the official names of this protein?
Cell division protein ZapD, Z ring-associated protein D.
What is the protein family that this protein belongs to?
Belongs to the ZapD family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to mid-cell in an FtsZ-dependent manner.
Protein: SURE_RHOPA
Sequence: MRILCTNDDGIHAPGLKTVEQIARAISDDVWVVAPELDQSGVSHSLSLNDPLRLREVGPRHFAVRGTPTDCVIMGSRFILKDKAPDLVLSGVNRGRNVAEDVVYSGTIAGALEGTILGLPSFALSQEFTIETRNAPLWETARTHAPDIIRKVMAAGVPKNTVVNINFPACTPDKVKGVVVTRQGKRNPGFLRIDERHDGRGNPYYWIGFERIKVEDMPAEGTDLAALAANFVSVTPLKLDRTDETFSAALANTLA
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBPA_HAEIN
Sequence: MQFKHFKLATLAAALAFSANSFADITVYNGQHKEAATAVAKAFEQETGIKVTLNSGKSEQLAGQLKEEGDKTPADVFYTEQTATFADLSEAGLLAPISEQTIQQTAQKGVPLAPKKDWIALSGRSRVVVYDHTKLSEKDMEKSVLDYATPKWKGKIGYVSTSGAFLEQVVALSKMKGDKVALNWLKGLKENGKLYAKNSVALQAVENGEVPAALINNYYWYNLAKEKGVENLKSRLYFVRHQDPGALVSYSGAAVLKASKNQAEAQKFVDFLASKKGQEALVAARAEYPLRADVVSPFNLEPYEKLEAPVVSATTAQDKEHAIKLIEEAGLK
What is the function of this protein?
Part of the ABC transporter complex FbpABC (TC 3. A. 1. 10. 1) involved in Fe(3+) ions import.  This protein specifically binds Fe(3+) and is involved in its transmembrane transport (By similarity).
What are the official names of this protein?
Iron-utilization periplasmic protein, Fe(3+)-binding protein, Iron-regulated 40 kDa protein, Major ferric iron-binding protein, MIRP.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 1 family.
What are the subcellular locations of this protein?
Periplasm.