PharMolix/UniProtQA huggingface dataset:
Protein: PA2H_LACMU
Sequence: SLVELGKMILQETGKNPVTSYGAYGCNCGVLGSGKPKDATDRCCYVHKCCYKKLTDCDPKKDRYSYSWKDKTIVCGENNSCLKELCECDKAVAICLRENLDTYNKKYNYLKPFCKKADPC
What is the function of this protein?
Snake venom phospholipase A2 homolog that lacks enzymatic activity (PubMed:29067765).  Shows moderate cytotoxicity against C2C12 myotubes (activity above 200 ug/mL) (PubMed:29067765).  Also shows antibacterial activity against both Gram-positive and Gram-negative bacteria (PubMed:29067765).  A model of myotoxic mechanism has been proposed: an apo Lys49-PLA2 is activated by the entrance of a hydrophobic molecule (e. g.  fatty acid) at the hydrophobic channel of the protein leading to a reorientation of a monomer (By similarity).  This reorientation causes a transition between 'inactive' to 'active' states, causing alignment of C-terminal and membrane-docking sites (MDoS) side-by-side and putting the membrane-disruption sites (MDiS) in the same plane, exposed to solvent and in a symmetric position for both monomers (By similarity).  The MDoS region stabilizes the toxin on membrane by the interaction of charged residues with phospholipid head groups (By similarity).  Subsequently, the MDiS region destabilizes the membrane with penetration of hydrophobic residues (By similarity).  This insertion causes a disorganization of the membrane, allowing an uncontrolled influx of ions (i. e.  calcium and sodium), and eventually triggering irreversible intracellular alterations and cell death (By similarity).
What are the official names of this protein?
Basic phospholipase A2 homolog LmutTX, svPLA2 homolog, LmmV toxin, Lys49 PLA2-like.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. K49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CREL1_HUMAN
Sequence: MAPWPPKGLVPAMLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGLERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWWFHKQQEAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVGSKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYKQMEGICVKEQIPESAGFFSEMTEDELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFIKGR
What is the function of this protein?
Protein disulfide isomerase (By similarity).  Promotes the localization of acetylcholine receptors (AChRs) to the plasma membrane (By similarity).
What are the official names of this protein?
Protein disulfide isomerase CRELD1, Cysteine-rich with EGF-like domain protein 1.
What is the protein family that this protein belongs to?
Belongs to the CRELD family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RECX_YERPE
Sequence: MNDQLSRAMRLLSQRDHSESELRRKLAAPPFSAKGNWGKRSGAKSSDVVESNLVESNPVESNLAESNAIEESDPQVIEQVIDYCYQHNWLDDSRFAASYINSRSRKGYGVQRIRSELMQKGVDKERILAAFENSEIDWCQLAKEVAQRKFSETLPVEWKEKAKVQRYLLYRGFFQEEIQSIYTDSVE
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_THIDA
Sequence: MSDAQTHGTVLAFDLGLKRTGVASGELAIGIAHPLTVIQAESTDARMAAIEKLAAEWQPALFVLGLPTRADGSENEMTRVARNFARRLESRFERPVFLIDERLTSATAESELHARGIHGKKNKALTDAVAAQLILQGFFDARLTA
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CNNM3_HUMAN
Sequence: MAAAVAAAGRLGWLFAALCLGNAAGEAAPGPRVLGFCLEEDGAAGAGWVRGGAARDTPDATFLLRLFGPGFANSSWSWVAPEGAGCREEAASPAGEWRALLRLRLRAEAVRPHSALLAVRVEPGGGAAEEAAPPWALGLGAAGLLALAALARGLQLSALALAPAEVQVLRESGSEAERAAARRLEPARRWAGCALGALLLLASLAQAALAVLLYRAAGQRAVPAVLGSAGLVFLVGEVVPAAVSGRWTLALAPRALGLSRLAVLLTLPVALPVGQLLELAARPGRLRERVLELARGGGDPYSDLSKGVLRCRTVEDVLTPLEDCFMLDASTVLDFGVLASIMQSGHTRIPVYEEERSNIVDMLYLKDLAFVDPEDCTPLSTITRFYNHPLHFVFNDTKLDAVLEEFKRGKSHLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEIIRSEILDESEDYRDTVVKRKPASLMAPLKRKEEFSLFKVSDDEYKVTISPQLLLATQRFLSREVDVFSPLRISEKVLLHLLKHPSVNQEVRFDESNRLATHHYLYQRSQPVDYFILILQGRVEVEIGKEGLKFENGAFTYYGVSALTVPSSVHQSPVSSLQPIRHDLQPDPGDGTHSSAYCPDYTVRALSDLQLIKVTRLQYLNALLATRAQNLPQSPENTDLQVIPGSQTRLLGEKTTTAAGSSHSRPGVPVEGSPGRNPGV
What is the function of this protein?
Probable metal transporter.
What are the official names of this protein?
Metal transporter CNNM3, Ancient conserved domain-containing protein 3, Cyclin-M3.
What is the protein family that this protein belongs to?
Belongs to the ACDP family.
Protein: CS1_COFCA
Sequence: MELQEVLHMNGGEGEASYAKNSSFNQLALAKVKPFLEQCIRELLRANLPNINKCIKVADLGCASGPNTLLTVRDTVQSIDKVRQEMKNELERPTIQVFLTDLFQNDFNSVFMLLPSFYRKLEKENGRKIGSCLIAAMPGSFHGRLFPEESMHFLHSSYSLQFLSQVPSGLVTELGITANKRSIYSSKASPPPVQKAYLDQFTKDFTTFLRMRSEELLSRGRMLLTCICKGDECDGPNTMDLLEMAINDLVVEGRLGEEKLDSFNVPIYTASVEEVKCMVEEEGSFEILYLQTFKLRYDAGFSIDDDCQVRSHSPEYSDEHARAAHVASLIRSVYEPILASHFGEAIIPDIFHRFATNAAKVIRLGKGFYNNLIISLAKKPEKSDV
What is the function of this protein?
May be involved in the biosynthesis of caffeine.
What are the official names of this protein?
Probable caffeine synthase MTL1, Methyltransferase-like 1, CcMTL1.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Type-7 methyltransferase family.
Protein: MRS2_CANGA
Sequence: MRPLVRYRLIPWCLRQAVCQPVSKPIGYRLISTRGGNRSPQGKKTIPLLNKPESSNVGAFPSAHQQLLSLKPITPNDSFISSTVFDSKGAIVAVSKKFQKWEFLRKHALYPRDLRKIDTSSVDIIPSIQVKPNNCIVLNMLHIKALIEKDRVYVFDTVDPSSAVKLGVLMYDLESKLSPKMGTQVQYYEHRALESILINIMSSLEAEFKLHYSICGQILIDLENEVNRDKLRELLIKSKNLTLFYQKSLLIREVLDELLESDDDLASLYLTVKKTEEDDFSDLEMLLETYYTQCDEYVQQAESLIQDIKSTEEIVNIILDANRNSLMLLELKITIYTLGFTVATLVPAFYGMNLKNFIEESYLGFGAVVVFSILSAYLVTRANFKALKSVTKLTMLKSSNPSQASYNMKTNSTLRPALARIRGLFKWRKNPDSNGQPIWNKQDRDVIWKWLMDEKK
What is the function of this protein?
High-conductance magnesium-selective channel that mediates the influx of magnesium into the mitochondrial matrix.  Essential for the splicing of mRNA group II introns in mitochondria by affecting mitochondrial magnesium concentrations, which are critical for group II intron splicing.  It also suppresses a variety of mitochondrial intron mutations and its absence may disturb the assembly of mitochondrial membrane complexes.
What are the official names of this protein?
Mitochondrial inner membrane magnesium transporter MRS2, RNA-splicing protein MRS2.
What is the protein family that this protein belongs to?
Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: A47_VAR67
Sequence: MGNKNIKPSKENRLSILYKDRMDSFKRGSWATSSFREKSHATIQRFLSLRREHVKVDHPDKFLELKREIYAIIQKSSSIDVDKRTKLMSNIKTMMINPFMIEGLMTSLESLDPDNKMSYSSVMILGEFDIINISDNKAAFEFINSLLKSLLLLNTSQLKLLEYSISNDLLYTHINALEYIIKNTFNVPERQLILRCQYLTPIFSDLLKYAGLTIKSNILMWNKKFIKPVSDLYTSMQLLHCVTV
What are the official names of this protein?
Protein A47.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus A47 protein family.
Protein: NDUB6_PONPY
Sequence: MTGYTPDEKLRLQQLRELRRRWLKDQELSPREPVLPPQKMGPMEKFWNKFLENKSPWRKMVHGVYQKSIFVFTHVLVPVWIIHYYMKYHVSEKPYGIVEKKSRIFPGDTILETGEVIPPMKEFPDQHH
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6, Complex I-B17, CI-B17, NADH-ubiquinone oxidoreductase B17 subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFB6 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
Protein: ATPI_CICAR
Sequence: MNVLLCSINTLNRFYDISALEVGQHFYWQIGDFQVHAQVLITSWVVIAILLISTILVVRNPQTIPTSGQNFFEYVLEFIRDVSKTQIGEEYGPWVPFIGTLFLFIFVSNWSGALLPWKIIKLPHGELAAPTNDINTTVALALLTSVAYFYAGISKKGLAYFGKYIQPTPILLPINILEDFTKPLSLSFRLFGNILADELVVVVLVSLVPLVIPIPVMFLGLFTSGIQALIFATLAAAYIGESMEGHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, chloroplastic, ATP synthase F0 sector subunit a, F-ATPase subunit IV.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: FADR_SALG2
Sequence: MVIKAQSPAGFAEEYIIESIWNNRFPPGTILPAERELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTKVNNFWETSGLNILETLARLDHESVPQLIDNLLSVRTNISTIFIRTALRQHPDKAQEVLATAHEVADHADAFADLDYNIFRGLAFASGNPIYGLILNGMKGLYTRIGRHYFANPEARSLALGFYHKLSSLCEQGAHDQVYETVRRYGHDSGEIWHRMQKNLPGDLAIQGR
What is the function of this protein?
Multifunctional regulator of fatty acid metabolism.
What are the official names of this protein?
Fatty acid metabolism regulator protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXA_RHIME
Sequence: MSETSIGPVALTMGDPAGIGPDITLSVWAKRADRPTPPFLYVGDPALLAARAKLLGQTVPICETDCPGAVAAFRQALPVWPVRSPAPVIPGNPDAANASAVTDAIDTAVRLVLAGEASALATNPISKAVLYEAGFRFPGHTEYLADLAARATGVAALPVMMLAGPKLRAVPVTIHIPLKDVPAALTPDLIYETCTITAADLRSRFGLPAPRLAIAGLNPHAGEGGALGREDDAVIRPVIDRLRAEGLDVVGPLPADTMFHDRARETYDVAICMYHDQALIPAKALGFDDSVNVTLGLPFIRTSPDHGTAFSLAGKGIAREESLLAALRLAAELARNAGGTKR
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTD_VIBVY
Sequence: MIALIQRVSEAAVRVDGEVVGQIDKGLLVLLGVEKDDDEAKAKRLMERVTTYRVFEDSEGKMNLNVQQVDGKVLVVSQFTLPADTKKGTRAGFSRGAHPADAERLYDYFSDLCQQVLPTERGRFAADMKVSLINDGPVTFWLQV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FCRL4_HUMAN
Sequence: MLLWASLLAFAPVCGQSAAAHKPVISVHPPWTTFFKGERVTLTCNGFQFYATEKTTWYHRHYWGEKLTLTPGNTLEVRESGLYRCQARGSPRSNPVRLLFSSDSLILQAPYSVFEGDTLVLRCHRRRKEKLTAVKYTWNGNILSISNKSWDLLIPQASSNNNGNYRCIGYGDENDVFRSNFKIIKIQELFPHPELKATDSQPTEGNSVNLSCETQLPPERSDTPLHFNFFRDGEVILSDWSTYPELQLPTVWRENSGSYWCGAETVRGNIHKHSPSLQIHVQRIPVSGVLLETQPSGGQAVEGEMLVLVCSVAEGTGDTTFSWHREDMQESLGRKTQRSLRAELELPAIRQSHAGGYYCTADNSYGPVQSMVLNVTVRETPGNRDGLVAAGATGGLLSALLLAVALLFHCWRRRKSGVGFLGDETRLPPAPGPGESSHSICPAQVELQSLYVDVHPKKGDLVYSEIQTTQLGEEEEANTSRTLLEDKDVSVVYSEVKTQHPDNSAGKISSKDEES
What is the function of this protein?
May function as an inhibitor of the B-cell receptor signaling.  May function in the B-cell-mediated immune response.
What are the official names of this protein?
Fc receptor-like protein 4, FcR-like protein 4, FcRL4, Fc receptor homolog 4, FcRH4, IFGP family protein 2, hIFGP2, Immune receptor translocation-associated protein 1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RPOA_PARDP
Sequence: MIHKNWAELIKPTQLEIKPGADSSRVATVVAEPLERGFGLTLGNALRRVLLSSLQGAAITSVQIDNVLHEFSSVPGVREDVTDIVLNLKGVTLKMDVDAPKRLTLSAKGPGEVKAGDIQESAGITILNRDHVICHLDEGAELHMELAVANGKGYVAADKNRPEDAPIGLIPIDAIFSPVKRVSYEVTPTREGQVLDYDKLTMKVETDGSLTPEDAVAYAARIIQDQLSVFVNFDEPETATRSDAEDGLEFDPRLLKKVDELELSVRSANCLKNDNIVYIGDLIQKTEAEMLRTPNFGRKSLNEIKEVLSGMGLHLGMDVVDWPPENIEDLAKRFDDQF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: KTHY_BACC1
Sequence: MKGLFVTIEGPEGSGKTTLIQGLLPYFEQKEQKVMATREPGGIAISEDIRTILHKQEYTMMEARTEALLYAAARRQHLVEKVMPALDEDYLVLCDRFIDSSLAYQGYARGLGMDKVFEINRFATEDCMPSLTIYLDIEPEVGLARIAKDAGREVNRLDMEDITFHKRVREGYLQVVERFSDRIVLVNADQPMEKLIEEVIQVIEDKLL
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: Y1108_LIGS1
Sequence: MAKQNQDENLITLVDEQGNETLYQELFNFHSDDYDKSYILLIPAGSEPEEQVDVLAFAFNPDENDDSQDYELFDIESDEEWEMVEGVLDTFLNDENMR
What are the official names of this protein?
UPF0473 protein LSL_1108.
What is the protein family that this protein belongs to?
Belongs to the UPF0473 family.
Protein: FRG1_CAEEL
Sequence: MPGADYSAVKGGGLKLKAGKKNLFKVGKEKKKKNKDDKEKIDPDTVENGGWRKIADEFDMKGGTNVAIEVASGAGSTRTYVAAMDNGKFTIGFPHPEGEGPNPEEIFALVKTPDDSKISLKTGFGRYVGVDSEYQLVAMAEAIGSREQFVLVFQEGKTAFQAVSSPLFLSTVPNKEGHIYVASRTATENEMVNIRTDAIQEGPVDWRSVEDRKNARECETAYVKMYQHSKVDLKNRHIAIDVKDKKGVKKAQADGSAHELLLDRRMKMKSDRYC
What is the function of this protein?
Binds to mRNA in a sequence-independent manner.  May play a role in regulation of pre-mRNA splicing or in the assembly of rRNA into ribosomal subunits.  May be involved in mRNA transport.  May be involved in epigenetic regulation of muscle differentiation through regulation of activity of the histone-lysine N-methyltransferase KMT5B (By similarity).
What are the official names of this protein?
Protein FRG1 homolog.
What is the protein family that this protein belongs to?
Belongs to the FRG1 family.
What are the subcellular locations of this protein?
Nucleus, Cajal body. Nucleus, nucleolus. Cytoplasm.
Protein: LV1E_MOUSE
Sequence: MAWISLILSLLALSSGAISQAVVTQESALTTSPGETVTLTCRSSTGAVTTSNYANWVQEKPDHLFTGLIGGTNNRAPGVPARFSGSLIGDKAALTITGTQTEDEAMYFCALWYSNHWVFGGGTKLTVLG
What are the official names of this protein?
Ig lambda-1 chain V region S43.
Protein: DXR_VIBC1
Sequence: MQKLTILGATGSIGASTLKVVEQNPELFSIVALAASTNVEKMVALCRKWQPKYAVMADKAAALALQSELASVSPSTEVLGGVDALCHVSALEEVDSVMAAIVGAAGLLPTMAAVKAGKRVLLANKEALVMSGQLFIDAVEEHGAELLPVDSEHNAIFQCLPQQVQTSLGRCNLEEHGISSILLTGSGGPFRYTDIAELEKVTPAQAIAHPNWSMGPKISVDSATMMNKGLEYIEAKWLFNAAREQLKVIIHPQSVIHSMVQYRDGSVLAQMGEPDMATPIALTMSYPSRVDAGVKPLDVTQVGELTFLQPDFARYPCLKLAIDACYEGQHATTALNAANEVAVDAFLNNRLGFTDIARINESVLNKITASHKSENVNSLESLIELDRMSRTIALEFLRERS
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: GREA_CAUVN
Sequence: MEKVPMTVAGYQTLDEELKRLKTVERPAVIAAIAEARSHGDLSENAEYHAAKERQGWIEGQIAEIEDKIARAQVIDVTKLSGKQVKFGATVSVVDEDTEEEARYQIVGDHEADVKSGRISLSSPLSRAMIGKEVGEVVEVNTPGGVKAYEILKVEWL
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: Y3170_HAEIE
Sequence: MTIENDYAKLKELMEFPAKMTFKVAGINREGLAQDLIQVVQKYIKGDYIPKEKRSSKGTYNSVSIDIIAENFDQVETLYKELAKVEGVKMVI
What are the official names of this protein?
UPF0250 protein CGSHiEE_03170.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.
Protein: DAPA_STRS2
Sequence: MSIQDLRDVKIITAMITPFKEDGSINFEVLPELIEHLLSHHTEGILLAGTTAESPTLTHEEELELFGAVQKIVNGRVPLIAGIGTNDTRDSIEFAKEVAAFGGFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVEMTPETMLRLAEHPNIIGVKECTSLANMAYLIEHKPEDFLIYTGEDGDAFHAMNLGADGVISVASHTNGDEMYEMFTAIEQQDIRTAAAIQRKFIPKVNALFSYPSPAPVKAVLNYLGFEVGPLRLPLVPCPEEDAKRIIKVVVDGDYEATKATVTGVVRPDY
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLOWR_DROSE
Sequence: MSFAEKITGLLARPNQQDPIGPEQPWYLKYGSRLLGIVAAFFAILFGLWNVFSIITLSVSCLVAGIIQMVAGFVVMLLEALCCFVCFEQVNVIADKVDSKPLYFRAGLYIAMAIPPIILCFGLASLFGSGLIFGTGVVYGMMALGKKASAEDMRAAAQQTFGGNTPAQTNDRAGIVNNAQPFSFTGAVGTDSNV
What is the function of this protein?
A calcium channel that regulates synaptic endocytosis and hence couples exo- with endocytosis.  Required in the nervous system and necessary in photoreceptor cells (By similarity).
What are the official names of this protein?
Calcium channel flower.
What is the protein family that this protein belongs to?
Belongs to the calcium channel flower family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Note=Upon fusion of the synaptic vesicle with the presynaptic membrane, protein is present in the periactive zones, where endocytosis is known to occur.
Protein: Y979_FRATF
Sequence: MAGHSKWANIKHKKAKEDAKRGKIFTKLIREITVAARLGGGDKDANPRLRAAIATALANNMSKDTIERAIVKGAGGDESANVEEVRYEGYGPGGVAIIVDCMTDNRNRTVGEVRHAFTKSGGNLGTDGSVAYMFTKRGIISFAPGVDEDALMEVALEAGAEDIITHEDGSIDVYTDPHDFSDIQEVLIEKGFNSENAEVTFDAETKAELDTETAEKVMALIDKLEDLDYVQSVYSNANFTQELIEQIG
What are the official names of this protein?
Probable transcriptional regulatory protein FTA_0979.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH_EHRCR
Sequence: MKDELNKVVIYTDGACSGNPGPGGWAAVLLFDDNEKTICGNDSDTTNNRMELTAVIEALKLLKVAYNVDLYTDSVYVKDGITLWIRKWKVNGWKTANKMPVKNLELWLELDSLANFHKVTWYWVRAHVGDLYNQKADMLARSQIVR
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SERC_ALIFM
Sequence: MEKVFNFCAGPAMLPVDVLAQAQKELVNWNGLGTSVMEISHRSKEFIKVAEESEQDLRDLLAIPSNYKVLFCQGGARAQFAAVPLNLLGGNTKADYVDAGYWAQSAVEEAQKYCTPNVINTIIDIDGKKAVQPASEWALSDDAAYVHFCPNETIDGIEINDLPVTDKPIVADMSSTILSRKIDVSKYGVIYAGAQKNIGPAGLTIVIVRDDLLDLASQALPSVLNYGVLADKESMFNTPPTYAWYLAGLVFKWLKSNGGIDAMETHNRKKAAVLYDYIDQSDFYRNDVHSDNRSLMNVPFQLANSELDTKFLELADEAGLKALKGHRVVGGMRASIYNAMPLEGVEALVQFMKEFEEKYV
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_BURTA
Sequence: MASETIVNLLDLDAEGLVAYCGGLGEKAFRAKQLQRWIHQYNAADFDGMTDLAKSLREKLKGRAVIGTPDILSDHVSADGTRKWLINVGNGNAVETVFIPEETRGTLCVSSQAGCAVNCRFCSTGKQGFSRNLSTGEIVGQLRMAEFALRASLGRAPGPNGKAERVITNVVMMGMGEPLLNYSAVVPAMRLMLDDNAYGLSRRRVTLSTSGVVPMMDRLGAELPVALAVSLHAPNDALRDELVPLNKKHPLRELMAACQRYLKVAPRDFITFEYCMLDGVNDTEAHARELLALTRDVPCKFNLIPFNPFPESGLLRSKTEQIKRFAQVLIDAGVVTTIRKTRGDDIDAACGQLAGAVKDRTRLAERTGATKIIEVRAV
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_CLOK5
Sequence: MKLHELKPAEGSRKSRKRIGRGTGSGLGRNAGKGEKGQKARAGGGVRIGFEGGQMPLYRRVPKRGFTNIFAKQYSELNVERLNIFEDGTEITPELLIEKRMIRKSKDGLKILGNGELQKKLTVKAVKFTKAAAQKIEAAGGKVEVI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: PRTB_MUGCE
Sequence: PRRRRETSRPIRRRRRARRAPIRRRRRVVRRRR
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Protamine-M6/M7, Mugiline beta.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: AMY6_HORVU
Sequence: MANKHMSLSLFIVLLGLSCSLASGQVLFQGFNWESWKHNGGWYNFLMGKVDDIAAAGVTHVWLPPASQSVAEQGYMPGRLYDLDASKYGNKAQLKSLIGALHGKAVKAIADIVINHRTAERKDGRGIYCIFEGGTPDARLDWGPHMICRDDRPYPDGTGNRPTRTRADFGAAPDIDHLNPRVQKELVEWLNWLRTDDGFDGWRFDFAKGYSADVAKIYVDRSEPSFAVAEIWTSLAYGGDGKPNLNQDPHRQELVNWVNKVGGSGPATTFDFTTKGILNVAVEGELWRLRGTDGKAPGMIGWWPAKAVTFVDNHDTGSTQHMWPFPSDRVMQGYAYILTHPGNPCIFYDHFFDWGLKEEIDRLVSIRTRQGIHSESKLQIMEADADLYLAEIEGKVIVKLGPRYDVGHLIPEGFKVVAHGNDYAVWEKV
What are the official names of this protein?
Alpha-amylase type B isozyme, 1,4-alpha-D-glucan glucanohydrolase, Clones GRAMY56 and 963.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: Y1105_STAS1
Sequence: MKINDLANHQKPRERMLNYGASHLSHAELLAILINTGRKGYSSLDIANELLKSIVNLKELKHLSINDLNKIKGVGLYKALTLKAAFELGERMHSGSVDDKIQINNPKDAADFMMGKMEHLTQEKFIALFLNSKNIIIKQKTIFMGTLNSAIVHPREIYSEAVKCASNAIIVLHNHPSGDTTPSLEDIKTTDRLRECGDILGIQLLDHVIIGDHTYLSMVEEGYFDI
What are the official names of this protein?
UPF0758 protein SSP1105.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.