PharMolix/UniProtQA huggingface dataset:
Protein: VATB2_HUMAN
Sequence: MALRAMRGIVNGAAPELPVPTGGPAVGAREQALAVSRNYLSQPRLTYKTVSGVNGPLVILDHVKFPRYAEIVHLTLPDGTKRSGQVLEVSGSKAVVQVFEGTSGIDAKKTSCEFTGDILRTPVSEDMLGRVFNGSGKPIDRGPVVLAEDFLDIMGQPINPQCRIYPEEMIQTGISAIDGMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKSKDVVDYSEENFAIVFAAMGVNMETARFFKSDFEENGSMDNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHADVSNQLYACYAIGKDVQAMKAVVGEEALTSDDLLYLEFLQKFERNFIAQGPYENRTVFETLDIGWQLLRIFPKEMLKRIPQSTLSEFYPRDSAKH
What is the function of this protein?
Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:33065002).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (PubMed:32001091).  In renal intercalated cells, can partially compensate the lack of ATP6V1B1 and mediate secretion of protons (H+) into the urine under base-line conditions but not in conditions of acid load (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit B, brain isoform, V-ATPase subunit B 2, Endomembrane proton pump 58 kDa subunit, HO57, Vacuolar proton pump subunit B 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Apical cell membrane. Melanosome. Cytoplasm. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Protein: VALC_STRHJ
Sequence: MTALTLAPCDLVVADLGGTTLRVGRITAGTSEVHDVKRVPTNGLGRYGALAPQELQDRVMEQLTREIAAHLTRPGQAPAQAVAVSFAGPMTADGVVLAGPTLWGGPAAPLPVADVLTQRLGLPVVAANDVTAAAWRYAAAEPEPFCLTTVSSGIGNKVFRHGEIVIDQLGYGGEIGHWLVDHAEDAAPCECGGRGHLGAIASGRGALFAVRAAAAADASAFARSALAGPSGGVPEAITNEAFAAAARAGDTFARESLRRSLRPLASAVSLLFTAIGVRRYLFVGGFALALGDTFLTLLGDELVRVGCFGLDEYATRAMLALGEDDDDHCLIGIGQLAAARLGAPRAVEVTA
What is the function of this protein?
Involved in the biosynthesis of the antifungal agent validamycin A.  Catalyzes the phosphorylation of valienone and validone to their 7-phosphate derivatives.
What are the official names of this protein?
C(7)-cyclitol 7-kinase.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family.
Protein: RPOC_EHRRG
Sequence: MKMLDLYGYTSIAQSFDKICISIASPESIRAMSYGEIKDISTTNYRTFKVEKGGLFCPKIFGPVNDDECLCGKYRKKRYRGVICEKCGVEVTSSKVRRERMGHIELVSPVAHVWFLKSLPSRIGALLDMPLKLIESILYSGDFVVIDPIATPLSKGEVISESAYNQAKDNYGEDSFIALTGAEAIRELLVRLDLHAINANLRSELESTTSEMKRKKIVKRLRIVENFINSGNKPEWMILTVIPILPPDLRPLVSLENGRPAVSDLNHHYRTIINRNNRLGKLLKLNPPAIMIRNEKRMLQEAVDALFDSTRRSYVSNKAGSVGYKKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPNLKLHQCGLPKKMALELFKPFICSKLKMYGIVPTVKLANKMIQNEKPEVWDILDEVIHEHPILLNRAPTLHRLGIQAFDPVLIEGKAIQLHPLVCSAFNADFDGDQMAVHIPLSLEAQLEARILMMSTNNILSPSNGKPIIVPSKDIILGIYYLTLQDYVEPEEILFFGDFSHVEYALHNKDIHICSKIKYKMNYCTDSSDGSGPTYYSKIVETTPGRLMLWQIFPEHKNLTFDLVNQVLTVKEITAIVDLVYRSCGQSETVEFSDKLMSLGFRYASQSGISFGRMDMIIPDTKTMHVDNASEKIKEFAVQYQDGLITKSERYNKVIDEWSKCTDLIAKDMMKAISVYDEESKLNSIYMMAHSGARGSASQMKQLAGMRGLMAKPSGEIIETPIISNFREGLNVFEYFNSTHGARKGLADTALKTANSGYLTRRLVDVAQDCIVVEYDCKTHNGFAMRSVIDGGTVVETLDNIILGRVAAVDIYNPITEELLVNAGELIDEAKVEKIRIAGLDAVKVRSPLTCEAKKGICALCYGRDLAIGDVVSIGEAVGVIAAQSVGEPGTQLTMRTFHVGGTAMRGVETSNLIAMLDAKVKLVNSNVVEDKYGNKIVMSRSCDVVLLDSVGNEKMRHSVPYGARLYVNDGQLVKITEKIADWDPYTMPIITEKTGIIKYMDLIDGVSINEVLDESTGISNRVVVDWKLHLQGANLRPRLVLVNDNGDIITLSSGLEANYFIPIGAVLSVQDGQKVHAGDVITRIPRESIKTRDITGGLPRVIELFEARRPKEHAIVSDIDGYVEFGKDYYRSKRRIFIKPVDDKLSPVEYLVPKGKHTIVNEGDFVHKGDLLMDGDPDPHDILRVLGVEALANYMIAEIQQVYRLQGVRIDNKHIEVILRQMLQKVEIFEPGDTMYLIGENVDVEEVLKTNSNMEKIGKSPAKYIPILQGITRASLDTNSFVSAASFQETTKVLTEAAFSGKEDSLYGLKENVIVGRLIPAGTGFLMNKIKKLSLLNKDDYSMYYNSEYQDLASIEAGHACSVSPSQGVSDTSGAVDY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: YIHI_SALPB
Sequence: MKKPTSAPRSKAFGKQRRKTREELNQEARDRKRLKKHRGHAPGSRAAGGNSASGGGNQNQQKDPRIGSKTPVPLGVTEKVTQQHKPKSEKPMLSPQAELDLLETDERLDALLERLEAGETLSAEDQAWVDAKLDRIDELMQKLGLSYDDDEEDDEEDEKQEDMMRLLRGGN
What is the function of this protein?
A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function.  May play a role in ribosome biogenesis.
What are the official names of this protein?
Der GTPase-activating protein YihI.
What is the protein family that this protein belongs to?
Belongs to the YihI family.
Protein: ATPB2_BURP6
Sequence: MADPQATNGTGAACAERDASDVGDVSDVGDARDEGAGRVVAVRGAVVDVAFDGGALPALNEALTIPVDGAAPILAEVHAHLSDAAVRALALGPTGGLRRGAAVRATGGPIRVPVGDAVLGRLLSVTGAPGDDGAALAADVERRPIHRGAPPLAEQKSANALFATGIKVIDLLAPLAQGGKAAMFGGAGVGKTVLVMELIHAMVERYRGISVFAGIGERSREGHEMLLDMRGSGVLGRTVLVYGQMNEPPGARWRVPLTALAIAEYFRDERAQNVLLLMDNVFRFVQAGAEVSGLLGRLPSRVGYQPTLASEVAALQERIASVEGAAVTAIEAVYVPADDFTDPAVTAIAAHVDSMVVLSRAMAAEGMYPAIDPVASSSILLDPLVVGEAHVEVAIEVRRVIEHYRELQDVIALLGIDELGADDRRLVGRARRLQRFLTQPFAVTEAFTGQAGASVEIADTIAGCRAILRGDCDDWRESSLYMVGTLDDARRKEAAAREADARREAAAAASGAGPGTTSDPASGSAEPQGARHGR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta 2, ATP synthase F1 sector subunit beta 2, F-ATPase subunit beta 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS7_TRIV2
Sequence: MSRRGVIQRRPVPPDSVYNSRLVSMIIRRIMRHGKKSLAARIVYDALKTIEERTGNNALEVFERAVRNATPLVEVKARRVGGATYQVPMEVRTERGTTLALRWLVQFSRSRPGRTMASRLANELLDAANESGNAIRKREETHRMAEANKAFAHYRY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: TP8L2_XENLA
Sequence: METFSSKDLALQAQKKILSRMASKSMVNMFIDETSSEILDELYRVSKEYTKNKTESQKVIKNLIKIAVKIGVLFRHNRFSPEELVLAKDFKNRLHNGAMTAISFYEVEFTFEKDVLPEILMECKNLVLRLVEKHLTPKSHGRIQHVFNHFADPEMLSQLYDTKSSLRPHLQKICNGLNKLIEEEKL
What is the function of this protein?
Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis.  Negative regulator of Toll-like receptor and T-cell receptor function.  Prevents hyperresponsiveness of the immune system and maintains immune homeostasis.  Inhibits jun/ap1 and NF-kappa-B activation.  Promotes Fas-induced apoptosis (By similarity).
What are the official names of this protein?
Tumor necrosis factor alpha-induced protein 8-like protein 2, TIPE2, TNF alpha-induced protein 8-like protein 2, TNFAIP8-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the TNFAIP8 family. TNFAIP8L2 subfamily.
Protein: SYH_PARUW
Sequence: MKFSIPPGVFDIIPTNTQEIWKSSYLWDFVERTIRKTVRDYGYQEIRTPLFERTELFQRSVGETSDIISKEMYTFEDKGGRSMSLRPEGTAPVMRSFIENQLHTIAPLQKLFYIAPMFRYERAQAGRYRQHHQFGAEAIGNSSPEQDAELIDLLYTLYKRLGLQNLSLNINSIGTISCRHTFRQALKDYLKPHLNNLSSDSQNRFETNPLRILDSKNAQDKQIVADAPSILDFLDEDSQIHFEQLKKLLKQLKIPYQVNPLLVRGLDYYNKTVFEVVVGELGAQNSIGGGGRYDGLLRELGGPDLPSIGFGTGIERIIQTMINQGIPLPSPCHPSLFLIPMGDEAKQLCFTLTHELRQQGIPTQMDFSGKKLGKVLQYADQIESTYVVVIGENELQTQEIELKELASGKKYKLTIDELAPTLKN
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_BURP0
Sequence: MSAALSRDATLLAFDYGEKRIGVAVGNLLTRTARALVIVRNLNREHRFKAVGELIAEWKPDALVVGLPLHPDGAPHEMTQRAMRFGNQLNGRFNLPVSWVDERYSSVEARAGLRARGDAADRVDAEAARVILQQYLDGLPDHHEFN
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPH_RABIT
Sequence: MLRFYLFISLLCLVRSDTDETCPSFTKLSFHSAVVGTELNVRLLLYTRKNYTCAQIINSTTFGNLNVTKKTTFVVHGFRPTGSPPVWLQDLVKALLMVEDMNLVVVDWNRGATTVIYTQASNKTRKVAIILKEFIDQMLARGASLDDIYMIGVSLGAHISGFVGKMYNGQLGRITGLDPAGPLFNGKPPQDRLDPSDAQFVDVIHSDTDALGYKEPLGNIDFYPNGGVDQPGCPKTIFEAGMQYFKCDHQMSVYLYLSSLRKNCTITAYPCDSYRDYRNGKCINCGLPQGKPCPLLGYYADNWKDYLSEKDPPMTKAFFDTAEKEPYCMYHYFVDIITWNKSIRRGSITIKLKDEAGNTTESKINHEPVTFEKYHQVSLLARFNQDLDKVAEISLVFSTGAVIGPKYKLRILRMKLRSLAHPERPQLCRYDLVLTENVETPFQPIVCQKLQM
What is the function of this protein?
Hydrolyzes specifically phosphatidic acid (PA) to produce 2-acyl lysophosphatidic acid (LPA; a potent bioactive lipid mediator) and fatty acid (By similarity).  Does not hydrolyze other phospholipids, like phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) or triacylglycerol (TG) (By similarity).
What are the official names of this protein?
Lipase member H, Lacrimal lipase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted. Cell membrane; Peripheral membrane protein.
Protein: EIF3E_ASPFU
Sequence: MAANVPPSAETLSSGAAAHPSNTAEEIANQYNLLPKLIPYLDRHLVFPLLEFSSGQDDEKEIVRAKYELLKHTNMTDYVANLWKEINNSDDIPDEFVKKREEVLAKLQQYEEESAKITQLLQDESVVANLRSDKVANLKFLEEQHGVTVEMVNSLYDYGRFQYSCGSYGNAAELLYQFRVLSTDNDKVASATWGKFASEILTTSWEAAMEEVQKVKDSIETRLFNNPLGQLQNRSWLIHWSLFPFFNHDPARDVLTDLFFSPAYINTIQTNCPWILRYLAAAVITNRNRAHKNSSVYQKQLKDLIRVVRQEGYEYNDPITDFIKALYVDFDFEEAQKKLGEAEEVLRSDFFLVSTTDAFVEAARHLISESYCKIHQRIDIKDLSTRLGLNQDEGEKWIVNLIRDTRVDAKIDYKEGTVIMNHPPQSVYQQVIEKTKGAFFRTQVLSAAVAK
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit E, eIF3e.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit E family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_FERNB
Sequence: MAKGRTTRTKQKKRVAVDHGVVHIKSTYNNTIISLTDPTGHVLSWASGGTTGFEGTRKGTPYAAQLAADKVAKDAVKMGIKRVDVIVKGPGAGRETAIRTLQAAGLEIDNIRDATPIPFNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: PTPB_STAAS
Sequence: MKILFVCTGNTCRSPLAESIAKEVMPNHQFESRGIFAVNNQGVSNYVEDLVEEHHLAETTLSQQFTEADLKADIILTMSYSHKELIEAHFGLQNHVFTLHEYVKEAGEVIDPYGGTKEMYVHTYEELVSLILKLKDIIC
What is the function of this protein?
Dephosphorylates the phosphotyrosine-containing proteins.
What are the official names of this protein?
Low molecular weight protein-tyrosine-phosphatase PtpB, Phosphotyrosine phosphatase B, PTPase B.
What is the protein family that this protein belongs to?
Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
Protein: YIT6_YEAST
Sequence: MSGTRCLLGVGLPVDVTATETLTHDEQGPGVEPGPCSRGSSIDGLLPSLLGPHDDVDDDSAAFHKYMTLSRDGAGAIHAPSLVEDASRNDDDDDDEDDDDSSMSRDLSKALDMSSSSSSSPRVQSRRHRSSVSAISAILHQGKSGREDITGSLSVPAEQEKLSFLAKASSIFFRRNSMPRDKHTHSVCPASRPDSERFIVTSAAAQSLRRQQQLEDAQYARVITNFRTIGWCSPSEIESVEYKRSLINAEWDEKISLLSHAQCYK
What are the official names of this protein?
Uncharacterized protein YIR016W.
Protein: SPT46_MACFA
Sequence: MENFSLLSISGPPISSSALSAFPDIMFSRATSLPDIAKTAVPTEASSPAQALPPQYQSITVRQGIQNTALSPDCSLGDTQHGEKLRRNCTIYRPWFSPYSYFVCADKESHPEAYDFPEVQQDEGKWDNCLSEDMAESICSSSSSAENTCPREATKKSRHGLDSITSQDILMASRWHPAQQNGYKCAACCRMYPTLDFLKSHIKRGFREGFSCKVYYRKLKALWSKEPKAWLGDRLSSGSCQAFNSPAEHLR
What is the function of this protein?
Plays a role in spermiogenesis and fertilization.
What are the official names of this protein?
Spermatogenesis-associated protein 46.
What are the subcellular locations of this protein?
Nucleus membrane. Note=Located throughout the subacrosomal area.
Protein: RS18_SYNFM
Sequence: MAIRRRRRTFHRRKVCRFCVDSELKIDYKDSKTLRYFVTERGKIVPRRISGNCAKHQRELTLAVKRARQIALLPHTTIHNV
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: ATG15_GIBZE
Sequence: MYKYGTVVDPAMTTNRRSRLSGFRCASTARVTATLLLSFLAFSPSSASSDFGDRFHDDIVLPPGPVLPSAPEIPEPAEHTFSLRHIYHHGTHLHPSLHRKRDVVHEQSRVYLAAEDDFSEYDILRLKAKSRPEPIHRLADRRPSVVDPMVAESRQRGYAAVLDASAWTMDQVSSPDIKDKDTVLTLALMTANAYVEHDTDADWEDVGERWNRSADFGWESDGLRGHVFVDDTNSTIVIGLKGTTTAVFDGEGTTTNDKVNDNLFFSCCCAQQGQWTWHQVCDCATGTYSCNNTCVVQALREENRYYGAARELYSNVTELYPDAQVWLTGHSLGGAVTSMLGMTYGLPVVTFEAVPEALPASRLGLPVPPGASAEYPQMRENTGTFHFGHTADPVYIGTCNGATASCTYGGYAMESTCHAGYECVYDVVADKGWRVGIGTHRIRSVIDDVIKKYDGVPECKRTPECRDCAQWKMYESNGTETTTTSSPSTTSTTRTRTRTSTCETPGWWGCLDKTTPVTTTTSTTSSSTSTCKTPGWFGCKDKTTSESSTTTTTEASPTTTCETPGRFWGCRDEVEATTTAKPGQVTNVPVTAAPTGTTDDSLSTALPETQRCLARNWFGICKEWAIDDLEFATDEM
What is the function of this protein?
Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies (By similarity).  Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles (By similarity).  The intravacuolar membrane disintegration by ATG15 is critical to life span extension (By similarity).  Autophagy is required for proper vegetative growth, asexual/sexual reproduction, and full virulence (PubMed:28894236).  Autophagy is particularly involved in the biosynthesis of deoxynivalenol (DON), an important virulence determinant (PubMed:28894236).
What are the official names of this protein?
Putative lipase ATG15, Autophagy-related protein 15.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Endosome, multivesicular body membrane; Single-pass type II membrane protein. Prevacuolar compartment membrane; Single-pass type II membrane protein. Note=From ER, targeted to vacuolar lumen at the MVB vesicles via the Golgi and the prevacuolar compartment (PVC).
Protein: RUVB_CUPNH
Sequence: MIETDKLAAPARVIAATPASSQEEAFERALRPKLLDEYVGQEKVRGQLDIFMHAARNRREALDHVLLFGPPGLGKTTLAHIIAREMGVNLRQTSGPVLERPGDLAALLTNLEANDVLFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSVKLDLQPFTLVGATTRAGMLTNPLRDRFGIVARLEFYTADELARIVTRSAQLLHARIDPQGALEIARRARGTPRIANRLLRRVRDYAEVKGDGNITRAMADAALAMLDVDSVGFDLMDRKLLEAVLHKFGGGPVGVDNLAAAIGEERDTIEDVLEPYLIQQGYLQRTPRGRVATAAAYRHFGLANPQGSGASELFGDA
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: RL16_MYCBT
Sequence: MLIPRKVKHRKQHHPRQRGIASGGTTVNFGDYGIQALEHAYVTNRQIESARIAINRHIKRGGKVWINIFPDRPLTKKPAETRMGSGKGSPEWWVANVKPGRVLFELSYPNEGVARAALTRAIHKLPIKARIITREEQF
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: PLIA1_BOTNU
Sequence: MRLILLSGLLLLGIFLANGDEVDREGKVVNSLIDALMHLQREFAKLKGSFLIVHKARSFGSGSERMYVTNKEIKNFEALRQICEQADGHIPSPQLENQNKAFANVLERHGKEAYLVVGDSANFTNWAAGEPNKAAGACVKADTHGSWHSASCDDNLLVVCEFYFIL
What is the function of this protein?
This phospholipase A2 inhibitor binds directly phospholipase A2 in the presence or absence of calcium.
What are the official names of this protein?
Phospholipase A2 inhibitor A1, alpha-PLI.
What is the protein family that this protein belongs to?
Belongs to the alpha-type phospholipase A2 inhibitor family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted in plasma.
Protein: TRFE_ORYLA
Sequence: MKPLLLLTLLGCLAAALAVPAQKVKWCVKSDQEFRKCSDLAAASPAFSCVKKESTLDCIIAIKAGEADAITVDGGDVYTAGLNNYDLHPIIAEDYGTSSETCYYAVAVAKKGTTFGIRDLRGKKSCHTGLGKSAGWNIPIGTLVSMDIIQWAGVEDKPVEEEVSTFFQASCVPGATRGSKLCELCKGDCSRSQKEPYYDYNGAFNCLAEGAGDVAFVKHLTVPDQEKSKYELLCRDNTRAPIDDYKKCNLARVPAHAIVTHKDPQLAELIWTSLNSVQNFNLFSSEAYAPSKNLMFKDSTQRLVKLPQNTDSFLYLGAQYMSIVRSLKKEQSVGTNSNAIKWCAVGHAETAKCDTWSINSVTDDTAAIECQNAPSVEECLKKIMRKEADAMAVDGGEVYTAGKCGLVPAMVEQYDAELCSSSGGQASSYYAVAVVKKDSGVTWENLKGKKSCHTGIGRTAGWNIPMGRIYDQTKDCDFTKFFPSGCAPEPKPALHCALCVKAAAKLSGDEAKCKARPEEQYYGYAGAFRCLAEGAGDVAFIKHTIVGENTDGNGPDWARSLKSDDYQLICPGKGPVPISEYASCNLAVVPAHAVVTRPESRSDVVRVLQVQQTFFGASGSDPSFKLFQSQNGNNLLFKDSTKCLQEVPAGTSYDQFLGSGYMEAMTSLRKCSDTASDLEKSCTFHSCQQT
What is the function of this protein?
Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate.
What are the official names of this protein?
Serotransferrin.
What is the protein family that this protein belongs to?
Belongs to the transferrin family.
What are the subcellular locations of this protein?
Secreted.
Protein: YQP1_CAEEL
Sequence: MRTQTFPPSSSSSRTTHPKKNRHSSNSSSMALVTPAKSSTGAAPKQSSQSGWDYWTRVYSDDAQTTGTPRDVRISDMLSSESLIRAKLLFLNVPSLPSAHKNIILNLVKRELNHDISIQDVVVVPPAKWFLNFYRPEDALKVMKHLNGYSYRGHILAVRFCYPDGTYGDESALTELVQCTNSAKGRILEKKDIVQDTFAVECWTKTEFDSLKVFEKELTNLLKAHAYLPYHTVLQSMRNLFTCKVQSELSSMFISDALAQWPTGLIRIFNRNVKVVSNTMCLSSSSYYTQRIHDSALEGGCSVHRNSWEPTVPDDIRSEVQLIQYTNSFLGHFGPQNIDVDIPIRILAQSLRGTWPKTGPKLAALLTEISSGFVLINRVLYLSSNLHHHEKIIDNLACFQDDCTDVYFLPLSCTTEDQKGKTVDYEDI
What are the official names of this protein?
Uncharacterized protein F07F6.1.
Protein: NDHI_MONRV
Sequence: MFPMVTEFMNYGQQTVRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSIIDDYTIRTILNLPEIKT
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: TPSN_CHICK
Sequence: MAAGLRLLLAGLCWSQFRVEDAASPPPPPAPVRCALLEGVGRGGGLPGGGNARPALLRFGGDAETPPEPGPEPEVTFNVSDPWGTLTPLGVPPRTPPSCELNPTNPQTGSDPWSRPLHPDARSPPTAGGQWWVAAVGTPQYGVTALLQGGMGTEGTITAAVALAVLTHTPTLRARVGSPIHLHCAFAAPPSSFVLEWRHQNRGAGRVLLAYDSSTARAPRAHPGAELLLGTRDGDGVTAVTLRLARPSPGDEGTYICSVFLPHGHTQTVLQLHVFEPPKVTLSPKNLVVAPGTSAELRCHVSGFYPLDVTVTWQRRAGGSGTSQSPRDTVMDSWTSGHRQAADGTYSRTAAARLIPARPQHHGDIYSCVVTHTALAKPMRVSVRLLLAGTEGPHLEDITGLFLVAFVLCGLIRWLYPKAARPKEETKKSQ
What is the function of this protein?
Involved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading).
What are the official names of this protein?
Tapasin, TPN, TPSN, TAP-associated protein, TAP-binding protein.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: SPEA_VIBCH
Sequence: MRYDVEQPSKLDRVRADYNVHYWSQGFFGIDDQGEVYVSPRKDKAHQTQLSSIVKQLEARDLNLPVLVRFPQILHQRVHNICDAFNQAIEEYDYPNKYLLVYPIKVNQQKEVVDEILASQAELEHKQLGLEAGSKPELLAVLAMAQQASSVIVCNGYKDREYIRLALIGEKLGHKVFIVLEKLSELDLVLKEAKSLGVKPRLGLRIRLASQGAGKWQSSGGEKSKFGLAASQVLTVINRLKAENQLEALQLVHFHLGSQMANIRDVRNGVNEAVRFYCELRELGAHIDFFDVGGGLAVDYDGTRSQSSNSMNYGLHEYARNIVSTVSDVCNLYGQPRPVIISESGRSITAHHAVLITNVIGTEAYSPEEIPAPGADAPMLLKNMWRGFEEVQHGTDDRALIEIYNDTQSDLSEAHSQFATGVLNLEHRAWAEQLSLRIYHELRQKMSNKNRFHRPILDELQERLADKFFVNFSLFQSLPDAWGIDQVFPVLPLSGLEEMNDRRAVMLDITCDSDGAVEQYVEGQGIESTLPVPAWTSDKPYLMGFFLVGAYQEILGDMHNLFGDTHSAVVNINDNGESEIAFINEGDTVEDMMRYVHIDVDKIRTNYRQLVSQRVAKEEQETVLAELELGLSGYTYLEDF
What is the function of this protein?
Catalyzes the biosynthesis of agmatine from arginine.
What are the official names of this protein?
Biosynthetic arginine decarboxylase, ADC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
Protein: NUOH_YERPG
Sequence: MSWFTPELIEILISVLKAVVILLVVVTCGAFMSFGERRLLGLFQNRYGPNRVGWGGSLQLVADMIKMFFKEDWVPRFSDRAIFTLAPVIAFTSLLLSFAIVPVSPTWAVADLNIGILFFLMMAGLAVYAVLFAGWASNNKYSLLGAMRASAQTLSYEVFLGLSLMGVVAQAGSFNMQDIVNSQEHVWNVIPQFFGFLTFAIAGVAVCHRHPFDQPEAEQELADGYHIEYSGMKFGLFFVGEYIGIVTVSALIVTLFFGGWQGPFLPPFIWFALKTAFFMVMFILIRASLPRPRYDQVMSFGWKVCLPLTLLNLLATAAVILYNAQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.