PharMolix/UniProtQA huggingface dataset:
Protein: SPKB_SYNY3
Sequence: MSFCVNPNCPHPKNPNNVQVCQACGNSLRLNGRYQTLGLLGKGGFGATFAAADVALPGTPICVVKQLRPQTDDPNVFRMAKELFEREAQTLGRVGNHPQVPRLLDYFEDDHQFYLVQEYVKGHNLHQEVKKNGTFTEGSVKQFLTEILPILDYIHSQKVIHRDIKPANLIRRQTDQKLVLIDFGAVKNQIDSVLSSNTSAQTALTAFAVGTAGFAPPEQMAMRPVYASDIYATGVTCLYLLTGKTPKEIDCNSQTGEMDWEKHVTVSSKFAEVIRKMLELSVRHRYKSAQQVLDALEMPTYEDGMMQGMVSTPFTTLTGAGDEPATGIRMGNSSSPDYGDPSTRFNTNVQPRDPSSTSLNTGIKTRTAKPRQSPRDRATSNIESPTTRVRPASNMADGGSVGAGGIDYNMVNPKPFSRREEEKQAIANQPETKRWNGKTFLAEYAQGKRDFADQNLVGIVLAKAFVPGINCYQANLTNANFEQAELTRADFGKARLKNVIFKGANLSDAYFGYADLRGADLRGANLNGVNFKYANLQGANFSGADLGSAKVSPEQLKLAKTNWRTVMPGSGRRR
What is the function of this protein?
Protein kinase required for cell motility, but not for phototaxis.
What are the official names of this protein?
Serine/threonine-protein kinase B.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: ARAA_OCEIH
Sequence: MLTLKEKEFWFVVGSQQLYGEEALQEVKAQAQTVTDALNESGALPYPIVLKDLAINADQITNVMKEVNYRDEVAGVITWMHTFSPAKMWIRGTKLLQKPLLHLATQFNESIPWDTIDMDFMNLNQSAHGDREYGFINARLNKQNKVVVGYWGKSEVQRQIAEWMDVAAAYNESFNVKVARFGDNMRNVAVTDGDKIEAQIQFGWTVDYFAIGDLVQYVNAVKEEEIDVLFAEYKDSYDFDYGDYSKDDWEASVRVQASYEIAIKRFLDDGGYNAFTSNFEDLYGMKQLPGLAVQRLMGQGYGFAGEGDWKTAALDRLLKVMSHNQSTGFMEDYTYELAEGKEAILQSHMLEVDPTLASTKPKITVFPLGIGDREDPARLVFDGKAGDGVVVSMADFGTHFKLLINEVNAFEPTTPAPNLPVARVLWEVKPNFQDGVKAWIENGGGHHTVVSLNLTTDQVVSYAKLVGLDYIVIK
What is the function of this protein?
Catalyzes the conversion of L-arabinose to L-ribulose.
What are the official names of this protein?
L-arabinose isomerase.
What is the protein family that this protein belongs to?
Belongs to the arabinose isomerase family.
Protein: HIS8_SALG2
Sequence: MSTENTLSVADLARENVRNLVPYQSARRLGGNGDVWLNANEFPTAVEFQLTQQTLNRYPECQPKAVIENYAQYAGVKPEQVLVSRGADEGIELVIRAFCEPGKDAILYCPPTYGMYSVSAETIGVERRTVPALENWQLDLQGISDNLDGTKVVFVCSPNNPTGQLINPQDLRTLLELTRGKAIVVADEAYIEFCPQATLTGWLVEYPHLVILRTLSKAFALAGLRCGFTLANEEVINLLLKVIAPYPLSTPVADIAAQALSPQGINAMRDRVAQTVQERQYLVNALQQTACVEHVFDSETNYILARFTASSSVFKSLWDQGIILRDQNKQPSLSGCLRITVGTRQENQRVIDALRAEPV
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: CLPX_CLOB8
Sequence: MAKYDEKKQLKCSFCGKTQEQVKRLIAGPGVYICDECIDLCSEIIADEFQETVDFDPKSVPKPNEIKEYLDSYVIGQERAKKSLAVAVYNHYKRINTNKEDIDVELSKSNILLLGPTGSGKTLLAQTLARFLNVPFAIADATTLTEAGYVGEDVENILLKLIQNADYDVEKAERGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQINTSNILFICGGAFDGVDKIIENRTRKSSMGFGAQIQAKHEKDVGSLLKEIMPADLLKFGLIPEFVGRLPILVTLESLDKEALIQILTKPKNALVKQYKKLFELDDVKLEFDEKSLIAIAEEAISRQTGARGLRAIIEDIMNEIMYEIPSDNRITNVIITEEAIKEKKQPRIERVEEGKIRPTLVKARTKKDIESA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: GLMU_COXBN
Sequence: MGLSVIILAAGQGKRMASSTPKILHPLGGIPLLERVVNTARLLNPHTIHVVYGNGGSHVREKLNYLPVHWIEQSQQLGTGHAVLQAIPFCQNEDRVLILYGDVPLISPKTLNSLLENTPSNGLGVVVAELPDPTGLGRIIRDDFGNILSIVEHKDVAEHQLKIREINTGIMTTTAMNLKKWLPQLNNNNCQKEYYLTDTVALAVAEGCPVGGVAAQCCEEVQGVNDRWELTKLERYYQRLMAKKLSLAGVTIIDPERFDARGENIEIAPDVVIDVNVILEGNVQLDRNVRIGPNVILKNTTVGENTEIHANSVIEAAVIKANCSVGPFARLRPGSVLEEGAKVGNFVEMKKTTLGRGSKANHLTYLGDTIIGKNVNVGAGTITCNYDGANKWQTKIEDGAFIGSNVALVAPLTVGKNATIGAGSTLSQDAPPDQLTVARERQRTIKGWHRPTKKE
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_BUCAI
Sequence: MLKIFNTLTSTKEIFTPIKKNRVNLYVCGVTVYDFCHIGHGRTFVVFDMIVRYLRFSGFQVKYVRNITDIDDKIISKSTKEKKKINTFTASMIKEMHKDFDLLGISVPDEEPRVTDYIDNIIRIITTLIKKKHAYIHKNGDVIFSIDSDPNYGTLSRQSLTSLESGSRIPLNNMKKNPLDFILWKSSNKEEYSWDSPWGKGRPGWHIECSAITNVFFNNSIDIHGGGSDLLFPHHENERSQSICFNNKSMINFWMHTGMVILNNKKMSKSLGNVYFLRNILKDCDAEVLRYFFLSTHYRHPIYYCEKNLDQAYTSLKYLYTALYDTNPFFNNEEGLNFELEFYNAMNDDFNTPAVFSIFFKIARKINFLKNKDILKTNKFAFRLKYLANNLGFLFQDPKEFLQKKTTLNLLTLKEIQLLIEKRNIARQSKLWQEADNIRKKLMSLDIILEDLPDKTIWRKNKKS
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YB1M_HERAU
Sequence: SMPPQVMVEINGMLNDGCTAFHEAKQVVEGNTIKIEVTTIRPKDAMCTQEISPFSTTIQVDAQLQPGEYTILVNDVAEALKL
What is the function of this protein?
Could be a silencing control element for the regulation of the restriction system.
What are the official names of this protein?
Uncharacterized 10.2 kDa protein in HgiBIM 5'region, ORF11, ORFC.
Protein: OPR9_ORYSJ
Sequence: MEDTHLLTPYKMGQLNLAHRIVHAPVSRFRSYGSMPQPHNLLYYAQRATPGALLIAEASAVSYAALGRSKDDAANGPIHRQRPGPPGFLFGTNLTDYNSATDGVKATESGVNDRNNLSKWWFMSRLNESGNAGGAEESHYTLPSSLDAPGLWNQEQIEAWRPIVDAVHAKGALFFCQIWHNGRVFSTDNPVTPQVSYFGNTDDLAPAAPQRLETGEIVQIVEDFRVAARNAIKAGFDGVEIHAANGHLLHQFMKASVNDRTDEYGGSVENRCRITVDAMSAVAEEIGADRVGVRLSPFADHCREEGTDPEEVALHLIGVMNGLGVLYCHVIEPRCMREQHRGAPRAPQRPAPPAPVQKGVPRHVHCERRVRPGGRGQGGRRRLRRPGVVREIVPGQPRPAGEVQAEGGSERV
What is the function of this protein?
Putative oxophytodienoate reductase that may be involved in the biosynthesis or metabolism of oxylipin signaling molecules.
What are the official names of this protein?
Putative 12-oxophytodienoate reductase 9, OPDA-reductase 9, OsOPR9.
What is the protein family that this protein belongs to?
Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.
Protein: MAO1_YERPY
Sequence: MELEYESKRPLYIPYAGPILLEFPLLNKGSAFTNDERNHFNLHGLLPEAVETIEEQAERAYRQYQDFKNDDDKHIYLRNIQDTNETLFYRLLEAHLSEMMPIIYTPTVGEACEHFSDIYRRARGLFISYPNREHIDDMLQNATKQNVKVIVVTDGERILGLGDQGIGGMGIPIGKLSLYTACGGISPAYTLPVVLDVGTNNPQRLNDPLYMGWRHPRISGDEYYAFVDEFIQAVKRRWPNVLLQFEDFAQKNATPLLNRYRDELCCFNDDIQGTAAVTLGSLIAASHAAGSQLRDQTVTFLGAGSAGCGIAEQIIAQMMSEGLSEIQARARIFMVDRFGLLTDKLPNLLDFQSKLVQKSDDLHHWNLHNDAISLLDVVRNAKPTVLIGVSGQPGLFTEELIREMHSHCARPIVMPLSNPTSRVEARPEDIINWTDGAALVATGSPFPPVSYKEKLYPIAQCNNSYIFPGIGLGVLASGASRVTDGMLMAASRALAESSPLARHGEGALLPNIDDIQAVSKAIAMRVGQAAQLQGVAIVTSEEALSKAIEHNYWQPQYRSYKRTSF
What are the official names of this protein?
NAD-dependent malic enzyme, NAD-ME.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
Protein: ALG44_PSEAE
Sequence: MNTAVNVNVVHESEAQRQFARVKLPARIRYIGANREGVDARLLDLSAGGFAFTASGAPIQPGDLYKGKLLFQVDSISFSLEVEFQVRSVDPASRRVGCEFQNLKPREVAALRYLITSYLAGEVIGVGDMLNTLQRENFTKARKQGGGNGGMGFFGRVRAVTLSTAIFVVGVGAFAFILNQMYNLYFVTHADSGVVSVPNQQITMPREGTVQSLLGPNAEVAKGAPIATFSANLLDMLKGNLTEEQLNPGNIEKLFGHQMKGTLTSPCDCRVVQQLVADGQYANKGQVIFTLAPRDSVASIEARFPYRNAAELAPGTRVNFQVAGDGVNRSGRIVNTAPVDGDLSSEIRVQIQPDQPLDAQYAGRPAEVSIGGLPGRTLLNKAVTLATAR
What is the function of this protein?
Required for alginate biosynthesis.
What are the official names of this protein?
Mannuronan synthase, Alginate biosynthesis protein Alg44.
What is the protein family that this protein belongs to?
Belongs to the Alg44 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RIMP_SHIB3
Sequence: MSTLEQKLTEMITAPVEALGFELVGIEFIRGRTSTLRIYIDSEDGINVDDCADVSHQVSAVLDVEDPITVAYNLEVSSPGLDRPLFTAEHYARFVGEEVTLVLRMAVQNRRKWQGVIKAVDGEMITVTVEGKDEVFALSNIQKANLVPHF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_BACFN
Sequence: MADNNSILEKLDGLVARFEEVSTLITDPAVIADQKRYVKLTKEYKELDDLMKARKEYMQLLANIEEAKDILSNESDADMREMAKEEMDNSQERLPVLEEEIKLLLVPADPQDGKNAILEIRGGTGGDEAAIFAGDLFRMYAKFCETKGWKMEVSSANEGAAGGYKEIICSVTGDNVYGTLKYESGVHRVQRVPATETQGRVHTSAASVAVLPEAEEFDVVINEGEIKWDTFRSGGAGGQNVNKVESGVRLRYIWKNPNTGVAEEILIECTETRDQPKNKERALARLRTFIYDKEHQKYIDDIASKRKTMVSTGDRSAKIRTYNYPQGRITDHRINYTIYNLAAFMDGDIQECIDKLTVAENAERLKESEL
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXK_BORPE
Sequence: MNAPRCLRRLLERQWRQGGWLSTLLRPLAALTGLVVARKRNAYLTGARAAWRAPVPVVVVGNIYVGGTGKTPVVIEVVRQLQARGWTPGVVSRGYGVDVGAAPRVGQGQLAAADYGDEPALIARATGAAIAVHPHRPRAVQALLRAHPGVDVVVSDDGLQHLALARDVEIVVQDERGVGNGRLLPVGPLREPAQRLADVDAIVTNAGRPRAAAAPAAGAPRQLAMWLEPTHAQRVTDGATRTLADLAALPPARLAAAAGIGNPARFFQTLEQAGIRPAHTLALPDHYAYAQSPFTALDADLILVTAKDAIKCAALDDPRLWAVQVGTRLSDPDFGDWLSATLRARQP
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: CCA_PSEA8
Sequence: MQIYKVGGAVRDRLLGRPVTDIDWVVVGASSDEMLARGYRPVGADFPVFLHPQSGEEYALARTERKSGRGYGGFTFHASPEVTLEEDLTRRDLTINAMAEDEQGRVIDPYGGQADLEARLLRHVSPAFAEDPLRVLRVARFAARYAGLGFRVAAETLALMRQLAESGELQALTPERSWKEISRALMEPNPEVFIQVLHDCGALAELIPEVEALFGVPQPAAHHPEIDTGVHVLSVLQQCARHRQPLSVRWACLLHDLGKGLTSEADWPRHIAHETRGVPLIDAVNQRFRVPRDCQELARLVGEYHTHAHRALELRPNTLLELLQSFDVYRRPQRFEEFVAASEMDARGRLGLEQRDYPQAAYLLGAAQAARAVSVKPLVEKGLKGAELGEALKCARLAALKAYKEERGKA
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: ISCA1_RAT
Sequence: MSASLVRATVRAVSKRKLQPTRAALTLTPSAVNKIKQLLKDKPEHVGLKVGVRTRGCNGLSYSLEYTKTKGDADEEVIQDGVRVFIEKKAQLTLLGTEMDYVEDKLSSEFVFNNPNIKGTCGCGESFNV
What is the function of this protein?
Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway.  Probably involved in the binding of an intermediate of Fe/S cluster assembly.
What are the official names of this protein?
Iron-sulfur cluster assembly 1 homolog, mitochondrial, HESB-like domain-containing protein 2, Iron-sulfur assembly protein IscA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: VM3S5_GLOBR
Sequence: NHNPECIVNEPLGTDIVSPPVCGNELLEVGEECDCGTPENCQNECCDAATCKLKSGSQCGHGDCCEQCKFSKSGTECRESMSECDPAEHCSGQCSECPADVFHKNGQPCLDNYGYCYNGNCPIMYHQCYALWGADVYEAEDSCFESNKKGNYYYGYCRKENGKKIPCAPEDVKCGRLYCKDNSPGQNGPC
What is the function of this protein?
Inhibits platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen.  Acts by inhibiting fibrinogen interaction with platelet receptors GPIIb/GPIIIa (ITGA2B/ITGB3) (By similarity).
What are the official names of this protein?
Zinc metalloproteinase/disintegrin.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-III subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TMEDB_DICDI
Sequence: MNKTNQLINICILVTLFLIGSSSALTLQVEPKSQECFYNFIESGKTSLLLYQVIRGGLLDINVKLTDPKGNTIFERLHFDTQMKGKQSFTAGESGAYKVCFNNEMSRFTAKVVTFTWASEEEGVKEVAKGDSITPMDQSVQKIERVLQSVIHEQKKLRYREQANRDTSESTNARVVWWTIAEVIVLVVMGVGQIWYLRKWFDNKSTGRV
What is the function of this protein?
Could have a role in the budding of coatomer-coated and other species of coated vesicles.
What are the official names of this protein?
Transmembrane emp24 domain-containing protein B.
What is the protein family that this protein belongs to?
Belongs to the EMP24/GP25L family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Single-pass type I membrane protein.
Protein: CRR29_ARATH
Sequence: MSSVFGSVHILAMIAIQLLLIHSVSSLNLTNAYLHHKCSNTQGKYKQGSAFEKNLNLVLSTITSIGNFRDGFRYTEEGEDPNNVFVMFQCRGDSYWSKCPPCISTAVSGLRRRCPRNKGAIIWYDQCLLKISSVASFNKIDYENDFYLSNPKNMSDRELFNKETSALLEKLANKASDRNNLDGKQLVLYAAGEKRIGTKKVSAMVQCTKDLIFTKCFECLEGILRKFPECCDGKQGGRVLGTSCNFRYELYPFLRN
What are the official names of this protein?
Cysteine-rich repeat secretory protein 29.
What is the protein family that this protein belongs to?
Belongs to the cysteine-rich repeat secretory protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS4_LACDB
Sequence: MSRYTGPSWKRSRRLGISLSGTGKELARRSYIPGQHGPNHRGRLSEYGMQLQEKQKLRWMFGLNERQFRTLFARAGKIREGQHGTNFMILLERRLDNVVYRLGLATTREQARQLVNHGHITVDGKRVDIPSYEVKVGQTISLKEKSKNLQQVKDALEAVASRPSFVSFDEDKMEGQLVRFPERDEMEPEIDEALVVEYYNKLL
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: UBE2A_MOUSE
Sequence: MSTPARRRLMRDFKRLQEDPPAGVSGAPSENNIMVWNAVIFGPEGTPFEDGTFKLTIEFTEEYPNKPPTVRFVSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKRVSAIVEQSWRDC
What is the function of this protein?
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.  In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1.  H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation.  In vitro catalyzes 'Lys-11', as well as 'Lys-48'-linked polyubiquitination.  Required for postreplication repair of UV-damaged DNA.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 A, E2 ubiquitin-conjugating enzyme A, RAD6 homolog A, HR6A, mHR6A, Ubiquitin carrier protein A, Ubiquitin-protein ligase A.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: HIS8_STAAR
Sequence: MKEQLNQLSAYQPGLSPRALKEKYGIEGDLYKLASNENLYGPSPKVKEAISAHLDELYYYPETGSPTLKAAISKHLNVDQSRILFGAGLDEVILMISRAVLTPGDTIVTSEATFGQYYHNAIVESANVIQVPLKDGGFDLDGILKEVNDDTSLVWLCNPNNPTGTYFNHESLDSFLSQVPSHVPVLIDEAYFEFVTAEDYPDTLALQQKYDNAFLLRTFSKAYGLAGLRVGYVVASEHAIEKWNIIRPPFNVTRISEYAAVAALEDQQYLKEVTHKNSVERERFYQLPQSEHFLPSQTNFIFVKTKRVNELYEALLNVGCITRPFPTGVRITIGFKEQNGKMLEVLSNFKYE
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: FPG_UREPA
Sequence: MPELPEVQTIVDYLNHHVLDIFIKKTIVHLPKILKNKTPQEFEKLLINHKIVKIKRLGKYLLFFLSNNLVLSVHLRMEGKFYYQAKEEWFNLAHTHIIIEFNNGMQLRYNDTRQFGTFHIYEQQSFLDSKELKKIALDPLDNNFSAQYLYEKLKKSNKAIKTALLDQSVVSGIGNIYADEILFAAKIFPTILAKNLTLKNYEKITKEAQRILLLSIKNKGTTIHTYKFGNDETGLFQKMLLVHTHAKEPCQICGTIIQKTKVNGRGTYYCPNCQN
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: RSMA_PHOLL
Sequence: MNNRVHQGHFARKRFGQNFLTDQFVIDSIAAAINPQPGQAVLEIGPGLGALTEPVGERMDKMTVVELDRDLAARLQVHPQLKDKLTIIQQDAMTVNFGELSQQRGKPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPGSKTFGRLSVMAQYYCQVIPVLEVPPTAFTPAPKVDSAVVRLVPHKSIPHPVKNIRMLSRITTQAFNQRRKTIRNSLGDLFTVEQLTELGIDPSTRAENISVEQYCKMANWLSEQPEMQS
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPSD_ABYKO
Sequence: YLVNPAAYAALGAYMFLLILIGFPINFLTLYVTLEHKKLRTPLNYILLNLAVANLFMVLGGFTTTMYTSMHGYFVLGRLGCNLEAFFATLGGEIALWSLVVLAIERWIVVCKPISNFRFTEDHAIMGLAFTWVMALACAVPPLVGWSRYIPEGMQCSCGVDYYTRAEGFNNESFVIYMFIVHFLIPLSVIFFCYGRLLCAVKEAPAAQQESETTQRAEKEVSRMVVIMVIGFLVCWLPYASVAWWIFCNQGSDFGPIFMTLPSFFAKSAAIYNPMIYICMNKQFRHCMI
What is the function of this protein?
Photoreceptor required for image-forming vision at low light intensity.  While most salt water fish species use retinal as chromophore, most freshwater fish use 3-dehydroretinal, or a mixture of retinal and 3-dehydroretinal (By similarity).  Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins.  Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity).
What are the official names of this protein?
Rhodopsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell projection, cilium, photoreceptor outer segment. Note=Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to disk membranes in the rod outer segment (OS) photosensory cilia.
Protein: MDTK_ECOHS
Sequence: MQKYISEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLIMLVLWNAGYIIRSMENIDPALAEKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSMRDIRNEKGTAKPDPAVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTVSLREQIALLYNDNPEVVTLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFYITFTAYWVLGLPSGYILALTDLVVEPMGPAGFWIGFIIGLTSAAIMMMLRMRFLQRMPSAIILQRASR
What is the function of this protein?
Multidrug efflux pump that functions probably as a Na(+)/drug antiporter.
What are the official names of this protein?
Multidrug resistance protein MdtK, Multidrug-efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ACPT_SALTI
Sequence: MYQIVLGKVSTLSAGQLPDALIAQAPQGVRRASWLAGRVLLSRALSPLPEMVYGEQGKPAFSAGTPLWFNLSHSGDTIALLLSDEGEVGCDIEVIRPRDNWRSLANAVFSLGEHAEMEAERPERQLAAFWRIWTRKEAIVKQRGGSAWQIVSVDSTLPSALSVSQCQLDTLSLAVCTPTPFTLTPQTITKAL
What is the function of this protein?
May be involved in an alternative pathway for phosphopantetheinyl transfer and holo-ACP synthesis.  The native apo-protein substrate is unknown.
What are the official names of this protein?
4'-phosphopantetheinyl transferase AcpT.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
Protein: EIF2D_MOUSE
Sequence: MFAKAFRVKSNTAIKGSDRRKLRADVTAAFPALGTDQISELIPGKEELNVVKLYVHKGDSVTVYTSGGNPILFELEKNLYPTVYTLWAYPDILPTFITWPLVLEKLVGGADLMLPGVVVPPTGLPQVQQGDLCAIALVGNRAPVAIGVAAMSTAQMLASGLKGKGVSVLHTYQDHLWRSGDKSSPPAIAPLDPTDSCEEKVHLGLQGNLKSLTLDGEEENGQVPLREASEDTSSRAPSQDSLDGKPLQEQMDDLLLRCFLHALKSRVKKADLPLLTSTLLGSHMFSCCPEGQQLDIKKSSYKKLSKFLQHMQQEQIVQVKELSKGVESIVAVDWRHPRITSFVIPEPSLTSQTVQEVSREQPYLPPDIKSLYCVPANMTQLFLESGHKKGSTLEGSEVRKIITDYAKRNRLVDADNRNLVKLDPILCDCILEKNEQHLVTKLPWDCLLTRCLKNMQPAYQVTFPGQEPILKKGKLCPIDITLALKTYNKKVTVVRNLETYGLDPCSVAAILQQRCQASTIVSPAPGAKDSLQVQVQGNQIHHLGQLLLEEYRLPGKYIQGLEKAPKPGKK
What is the function of this protein?
Translation initiation factor that is able to deliver tRNA to the P-site of the eukaryotic ribosome in a GTP-independent manner.  The binding of Met-tRNA(I) occurs after the AUG codon finds its position in the P-site of 40S ribosomes, the situation that takes place during initiation complex formation on some specific RNAs.  Its activity in tRNA binding with 40S subunits does not require the presence of the aminoacyl moiety.  Possesses the unique ability to deliver non-Met (elongator) tRNAs into the P-site of the 40S subunit.  In addition to its role in initiation, can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits (By similarity).
What are the official names of this protein?
Eukaryotic translation initiation factor 2D, eIF2D, Ligatin.
What is the protein family that this protein belongs to?
Belongs to the eIF2D family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STK40_CHICK
Sequence: MKRRASDRGAGETSTKAKALCTGISGNNAKRAGPFILGPRLGNSPVPSIVQCLARKDGTDDFYQLKILTLEERGDKGIETQEERQGKMLLHTEYSLLSLLHNQEGVVHHHGLFQDRACEIIEDLEANRMVRKMKKRICLVLDCLCAHDFSDKTADLINLQHYVIKEKRLSERETVVIFYDVVRVVEALHKKNIVHRDLKLGNMVLNKRTHRITITNFCLGKHLVSEDDLLKDQRGSPAYISPDVLSGRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQELFRKIKAAEYTIPEDGRVSENTVCLIRKLLVLDPQQRLTASEELDSLSSIIASWQSMSLLSGPLQVVPDIDDQVANPEHPQEAKVTEECSQYEFENYMRQQLLLAEEKNTLHEAKSFLQKRQFGNIPPVRRLGHDAQPMNPLDAAILAQRYLRK
What is the function of this protein?
May be a negative regulator of NF-kappa-B and p53-mediated gene transcription.
What are the official names of this protein?
Serine/threonine-protein kinase 40, Serine/threonine-protein kinase lyk4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.