PharMolix/UniProtQA huggingface dataset:
Protein: EFTU_CLOBH
Sequence: MAKAKFERSKPHVNIGTIGHVDHGKTTLTAAITTVLAQKGGASATKYDEIDKAPEEKERGITINTSHVEYETANRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLASRVGVQYIVVFLNKADQVDDPELIELVEMEVRELLNEYGFPGDDTPIVVGSALEVLENQDNAEKTKCIDELMEAIDSYIPTPERATDQPFLMPVEDVFTITGRGTVATGRVERGVLHTGDEVELIGMKQEVSKTVCTGIEMFRKILDEAMAGDNIGALLRGIQRDEIQRGQVLAKPGSVTPHKKFVGQVYVLKKEEGGRHTPFFNGYRPQFYFRTTDVTGSINLPEGVEMVMPGDHIDMAVELITPVAMHENLRFAIREGGRTVGSGVVTTISE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F16PA_METFK
Sequence: MLKLSEFLVQQERQHAVADNVLTLIQDIAATCQAVAREIRYGALRGNMGSAGRENVQGEEQKALDVISNDIFTAMASKQPHVAAVASEEMAQAQVFAGKQGKYLLVFDPLDGSSNVNLNLSVGSIFSILPAPEGSVDEASFLQAGSRQLAAGYALYGTSTMLVLTMGHGVHGFTLDPDQGEFYLTHPGLTIAASTEEFAINMSNQRFWQPPVQRYIAECIAGSSGPRGKDFNMRWVATMVAEVHRLLVRGGVFLYPLDSRAVGRGGRLRLLYEANPMSLLVEQAGGLATTGHRRILDVEPAGLHQRVAVMMGAREEVERLQDYHSFTDPTA
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_STAAB
Sequence: MSRKESRVQAFQTLFQLEMKDSDLTINEAISFIKDGNPDLDFEFIHWLVSGVKDHEPVLDETISPYLKDWTIARLLKTDRIILRMATYEILHSDTPAKVVMNEAVELTKQFSDDDHYKFINGVLSNIKK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: PLSX_FRATF
Sequence: MGYKISIDAMGGDHGLNTTIPAALEAVKKDSNLQIVLVGDHHKIKRALDRYSKVKKIKLPVLQRIAIHHASETVGMDESPSIAVRKKKDSSMRVAINLVKDRTVDACVSAGNTGALMATSKFVLKTINGVDRPAIVYALPAFNRETKQLSKTYMLDLGANVVCTSEQLFQFAIMGSILAASSKGIAEPRVSLLNIGEEEMKGLDNIKNAAKLLQGCDFINYNGYIEGKYIFDDTTDVIVCDGFVGNVSLKTMEGSLRLIESLIKKTIQESSLLMKIPIVMALPIFKKMKKGMNLDSFNGASLLGLTGIVVKSHGGASANAFETAIYEAIKEIKYNIPKTIQESLEKVL
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: VAPC4_METJA
Sequence: MYKIVPDTNFLIYVFKHKINFDYEIERALNTKFEIVILSPIKEELERLLKSRDLKGKEKLAVNLALAKIKNYKLVDYTANYADEAILNYAKENENVIVATNDKELKEKLMENNIPVMVVRQKKYFEIFGMV
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  An RNase.  Its cognate antitoxin is VapB4 (By similarity).
What are the official names of this protein?
Ribonuclease VapC4, RNase VapC4, Putative toxin VapC4.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: PDXT_ROSCS
Sequence: MTVGILALQGDFREHEEMLRRIGAPTLQVRLPKHLDRVERLIIPGGESTTIGKLLAMYGLIEPLRARVREGMPIWGTCAGAILMAQRIADGRADQPSLRLMAVTARRNAFGSQLESFEIDLPVEALGGESLRMVFIRAPVLEDLGDDVTPLARLEDGRVVAARQANMLATCFHPELTSDERMHRYFLEM
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: CDC45_XENLA
Sequence: MFVSDLRKEFFDVIVTERVLLLVAPDVDALCACKILQALFQCDHVQYTLVPVSGWQELETLFLEHKEQFRYFVLINCGANIDLLETLQPQEEAIFYICDTHRPIDVVNIYNDSQVKLLIRQDDDLEIPAYDDIFNDDEEDGEDSGNESDGAEPSGKRRRFDEAAVERRIERRRQRREWEARRREIIFDYEQYEYHGTSSAMMMFELAWIMSKDSNDMLWWAIVGLTDQWVQDRITQMKYVTDVGTLQRHVSRHNHRNEDEENSLSIDCMRIAFEYDLRLSLYQHWSLYESICNSCYTSATLKLWSLQGQKKLQEFLADMGMPLKQVKQKFNSMDISLKENLREMLEESANKFGMKDVRVQTFSVQFGFKNKFLASDIVFAVLSLLENTERDEKGTDNFIKALDSLSRSNLDKLHTGLEMGKKLLCAIQQTVASCICTNLILSQGPFLYCYLMEGTPDVKMFSNPISLCLLCKYLLKSFVCSTKNKRCKLLPLVLAAPLDAEKGTVIMVGIPPEAESSDKKNFFGRAFEKAAESTSSRTLHNHFDMSIIELRTEDRSKFLDALISLLS
What is the function of this protein?
Required for initiation of chromosomal DNA replication.  Binds to chromatin in a mutually dependent manner with the GINS DNA replication complex.
What are the official names of this protein?
Cell division control protein 45 homolog.
What is the protein family that this protein belongs to?
Belongs to the CDC45 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Associates with chromatin.
Protein: YL245_MIMIV
Sequence: MVTKWKKICLFDNYEISNTGKIRNSKSGKLLKFSMRKGYYCCSLSKNNTKKTFNVHRLVARIFINNPSKFNVVNHKDGNKLNNNSSNLEWTNYKHNANHAITNGLKKIFRKKIHQYDINGNYIDSFESINNAGLYTGINPKHISSTCLGKRKTCGGFIWEYDKKFSKEKKNGLPLENNNNYLITKDGRVFSKRANKYLKPKIDPDGYLLVSISTNNVNKQISIHRLVAMTYIENPNNYPYVNHIDNNKQNNNITNLEWCTPKQNMIHHIKTRTKIYTVKVAQYDMNYNVITSYASIKEAGEKTGIDKSSIVRVCKGKQKYAGKYIWSYIN
What are the official names of this protein?
Uncharacterized HNH endonuclease L245.
Protein: PANB_XANAC
Sequence: MSSHADSKPWTVPALAQAKREGRKLVMLTAYDAGFARTFDANGVDLILVGDSLGMVVQGHDSTLPVTTADMVYHTASVARALDRALLVADLSFQADATPERALDAATQLLQAGAEMVKIEGAGHKLEVIRYLVEREIPVCSHLGLTPQSVLRFGGYKVQGRGEAGEQLRRDAQAVVDAGASLLVLECVPTPIATQISAELSVPTIGIGAGPGCDGQVLVMHDMLGLDSGHRRPKFVKDFLAEGGSVAGAVRAYAQAVRDGSFPDAEHAYAA
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGB_HORSE
Sequence: MAAPAARADGSDAALAAALADVPDLGRLLEVDPYLKPYAPDFQRRYNRFSQTLDNIGKNEGGIDKFSRGYESFGVHRCADGGLYCKEWAPGAEGVFLTGDFNDWNPFSYPYKKLDYGKWDLYIPPKPNKSLLVPHGSKLKVVIRSKSGEILYRISPWAKYVVRESGNVNYDWIHWDPEQPYKFKHSRPKKPRSLRIYESHVGISSHEGKIASYKHFTCNVLPRIKGLGYNCIQMMAIMEHAYYASFGYQITSFFAASSRYGTPEELKELVDTAHSMGITVLLDVVHSHASKNSEDGLNMFDGTDSCYFHSGPRGTHDLWDSRLFIYSSWEVLRFLLSNIRWWLEEYGFDGFRFDGVTSMLYHHHGIGASFSGDYHEYFGLQVDEDALTYLMLANHLVHTLYPDSITIAEDVSGMPALCSPISQGGGGFDYRLAMAIPDKWIQLVKEFKDEDWNMGNIVYTLTNRRHLEKCIAYAESHDQALVGDKSLAFWLMDAEMYTNMSVLTPFTPVIDRGIQLHKMIRLITHALGGEGYLNFMGNEFGHPEWLDFPRKGNNESYHYARRQFHLTDDDLLRYKFLNNFDRDMNKLEERCGWLSAPQAFVSEKHEGNKVIAFERAALLFIFNFHPSKSYTNYRVGTTLPGKFKIVLDSDAAEYGGHQRLDHNTDFFSEPYEHNERPSSLLVYIPSRVALILQNVDPPN
What is the function of this protein?
Required for normal glycogen accumulation.  The alpha 1-6 branches of glycogen play an important role in increasing the solubility of the molecule.
What are the official names of this protein?
1,4-alpha-glucan-branching enzyme, Brancher enzyme, Glycogen-branching enzyme.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: PEPB_YERP3
Sequence: MTTEIMQISLSHNPADARWGEKALISTNDQGVTIHLTSHDQLGGIQRAARKIDGQGIKQVKLAGEGWGLEQSWAFWQGFRGPKGQRSVVWAELPANEKTELEQRLQIIDWVRDTINAPAEDLGPEQLAKNAIDLLCAVSCDAVSYRITKGEDLREQNYAGIYTVGRGSDRAPVLLALDYNPTGNPDAPVMACLVGKGITFDSGGYSLKQSAFMDSMKSDMGGAATLTGALALAAARGLKERVKLYLCCADNMVSGNAFKLGDIIRYRNGKTVEIMNTDAEGRLVLADGLIDASEQNAPLIIDAATLTGAAKTALGNDYHALFSFDDELAQALLTSAHSEHELFWRLPLAEFHRSQLPSNFAELNNVAGGAYSAGASTAAAFLSHFVKNYQQGWLHIDCSATYRKSAVDQWSAGATGLGVRTVANLLLAQAKQ
What is the function of this protein?
Probably plays an important role in intracellular peptide degradation.
What are the official names of this protein?
Peptidase B, Aminopeptidase B.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IDHG2_MOUSE
Sequence: MLAVTSCSMKTVLQYAVFLGHSREVVCELVTSFRSFCSHCAVPPSPKYGGRHTVAMIPGDGIGPELMVHVKKIFRSNCVPVDFEEVWVTSTSNEEEINNALMAIRRNRVALKGNIATNHNLPARYKSHNTKFRTILDLYASVVHFKTFPGVMTRHKDIDILVVRENTEGEYTNLEHESVKGVVESLKIVTKTKSVRIADYAFKLAQKMGRKKVTVVHKANIMKLGDGLFLQCCKDVAAHYPQITLESMIIDNTTMQLVSKPQQFDVMVMPNLYGNIINSICTGLVGGSGIVPGANYGDSYAIFEMGSKEIGKDLAHRNIANPVAMLLTSCIMLDYLDLQPYATHIRSAVMASLQNKAVCTPDIGGQGNTASTVEYILHHMKEQTSGCHPNFFLQFT
What is the function of this protein?
Regulatory subunit which plays a role in the allosteric regulation of the enzyme catalyzing the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate.  The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers.
What are the official names of this protein?
Probable isocitrate dehydrogenase [NAD] gamma 2, mitochondrial, Isocitric dehydrogenase subunit gamma 2, NAD(+)-specific ICDH subunit gamma 2.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
Protein: SEPF_ENTFA
Sequence: MSIFNKDALSSFFGLSGEEDDYYDNYEEYEERKAVNEPPRRAARPKPQRPVQQQESYSQPAYTQQSEPVVEKPSARYRSAEAHQERDTQQAAYTEKKVVSMRSSNQSATTNTRRAQESTANAKTHKITIIEPRVYSEAMSIAKHLFAEEAVLVNFTLVEEDQARRIVDFLTGTVYALDGDIQRVGNEIFLCTPANMEIDSATAQSLANKQFFDF
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: GLYA_BACC2
Sequence: MDHLKRQDEKVFAAIEAELGRQRSKIELIASENFVSEAVMEAQGSVLTNKYAEGYPGKRYYGGCEHVDVVEDIARDRVKEIFGAEHVNVQPHSGAQANMAVYFTILEQGDTVLGMNLSHGGHLTHGSPVNFSGVQYNFVEYGVDADSHRINYDDVLAKAKEHKPKLIVAGASAYPRVIDFKRFREIADEVGAYLMVDMAHIAGLVAAGLHPNPVPHAHFVTTTTHKTLRGPRGGMILCEEKFAKQIDKSIFPGIQGGPLMHVIAAKAVAFGETLQEDFKTYAQNIINNANRLAEGLQKEGLTLVSGGTDNHLILIDVRNLEITGKVAEHVLDEVGITVNKNTIPFETASPFVTSGVRIGTAAVTSRGFGLEEMDEIASLIAYTLKNHENEAALEEARKRVEALTSKFSMYPNL
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERA_RALSO
Sequence: MPEGFRCGMVAIVGRPNVGKSTLMNALVGQKVSITSRKAQTTRHRITGIQTTDDAQFVFVDTPGFQTRHATALNRSLNRAVTSTLTSVDAVLFVVEAGRYGPDDAKVLSLLPRETPVILIVNKVDRLDAYTRAEMVAVFLQEMAQVFPFKEIVPMSAKNRDDILRLLGIVRPYLPEGEPMYDPEALTDRSERFLAAEIVREKVFRWTGDELPYSSTVVVDKFETEGRLRRVFVTILVDRDAHKAMIIGAKGAKLKQISTEARMDMEKLFDGKVYLEVWVKVKSGWADNEAGLRAYGYE
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: METN_XANCP
Sequence: MIQFQRLHKSYTVDGRQIVALHPLDLRIGPGEVFGIIGHSGAGKSTLIRLINRLEEPTGGRLLIGDEDVTALNSTGLRALRRRVGMIFQHFNLLSSRTVAGNVAFPLELAGTPRAEIDARVAELLARVGLEQHATKYPAQLSGGQKQRVGIARALATRPQILLCDEATSALDPQTTASVLQLLAQINRELGLTIVLITHEMEVIRRVCDRVAVLDAGKLVETGPVTEVFLHPQHPTTRRFVSEAEHVDEAELHRDFEAVGGRIVRLTFLGNGTYEPVLGRIARETGVDYNILSGRVDRIKDTPYGQLTVALTGGDQNAARAGFVAAGVHVEDLRV
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ASTD_SALAR
Sequence: MTLWINGDWITGQGERRSKTNPVSAEILWQGNDADTAQVAGACEAARAAFPCWARQPFAARQAIVEKFAVLLEEHKAELTAVIARETGKPRWEAATEVTAMINKIAISIKAYHARTGEQTSELADGAATLRHRPHGVLAVFGPYNFPGHLPNGHIVPALLAGNTLIFKPSELTPWTGETVIKLWERAGLPAGVLNLVQGGRETGHALSLLDDLDGLLFTGSASTGYQLHRQLSGQPKKILALEMGGNNPLIIEDAEDIDAAVHLTLQSAFITAGQRCTCARRLLVKQGVQGDAFLARLVDVAGRLQPGRWDDDPQPFIGGLISAQAAQHVIEAWHQREALGGRTLLAPRKVKEGTSLLTPGIIELTGVTDVPDEEVFGPLLSVWRYDHFDEAIHLANSTRFGLSCGLVSTDRAQFEQLLLEARAGIVNWNKPLTGAASTSPFGGVGASGNHRPSAWYAADYCAWPMATLESPELTLPATLSPGLDFSRREAV
What is the function of this protein?
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
What are the official names of this protein?
N-succinylglutamate 5-semialdehyde dehydrogenase, Succinylglutamic semialdehyde dehydrogenase, SGSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. AstD subfamily.
Protein: Y2033_YERP3
Sequence: MAGHSKWANTKHRKAAQDAKRGKIFTKIIRELVTAARLGGGDPGANPRLRAAIDKALSNNMTRDTLNRAIARGVGGDEDNNMETIIYEGYGPGGTAVMVECLSDNRNRTVSEVRHAFTKTGGNLGTDGSVSYLFTKKGVISYAPGLEEDTVMDAALEAGADDIVVYDDGAIDVFTAWESLGAVKDALDATGLVAEGAEVSLIPSTKAELDAETAPKLLRLIDMLEDSDDVQEVYHNGEISDEVAATL
What are the official names of this protein?
Probable transcriptional regulatory protein YpsIP31758_2033.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_CHLTA
Sequence: MFKCPERVSIKKKEDILDLPNLVEVQIKSYKQFLQIGKLAEERENIGLEEVFREIFPIKSYNEATILEYLSYNLGVPKYSPEECIRRGITYSVTLKVRFRLTDETGIKEEEVYMGTIPIMTDKGTFIINGAERVVVSQVHRSPGINFEQEKHSKGNVLFSFRIIPYRGSWLEAVFDINDLIYIHIDRKKRRRKILAMTFIRALGYSTDADIIEEFFSVEERSLRLEKDFVALVGKVLADNVVDADSSLVYGKAGEKLSTAMLKRILDAGVQSLKIAVGADENHPIIKMLTKDPTDSYEAALKDFYRRLRPGEPATLVNARSTIMRLFFDAKRYNLGRVGRYKLNKKLGFPLDDETLSQVTLRKEDVIGALKYLIRLRMGDEKTSIDDIDHLANRRVRSVGELIQNHCRSGLARMEKIVRERMNLFDFSSDTLTPGKIISAKGLVSVLKDFFSRSQLSQFMDQTNPVAELTHKRRLSALGPGGLNRERAGFEVRDVHASHYGRICPIETPEGPNIGLITSLSSFAKINEFGFIETPYRVVRDGIVTDEIEYMTADVEEECVIAQASAELDEYNMFKTPVCWARYKGEAFEADTSTVTHMDVSPKQLVSVVTGLIPFLEHDDANRALMGSNMQRQAVPLLKTEAAIVGTGLEGRAAKDSGAIIVAQEDGVVEYVDSYEIVVAKKNNPTLKDRYQLKKFLRSNSGTCINQTPLCSVGDVVTHGDVLADGPATDKGELALGKNVLVAFMPWYGYNFEDAIIISERLIKQDAYTSIYIEEFELTARDTKLGKEEITRDIPNVSEEVLANLGEDGIVRIGAEVKPGDILVGKITPKSETELAPEERLLRAIFGEKAADVKDASLTVPPGTEGVVMDVKVFSRKDRLSKSDDELVEEAVHLKDLQKEYKSQLAQLKVEHREKLGALLLNEKAPAAIIHRRSADILVQEGAIFDQETIELLERESLVDLLMAPCDMYDVLKDILSSYETAVQRLEVNYKTEAEHIKEGDADLDHGVIRQVKVYVASKRKLQVGDKMAGRHGNKGVVSKIVPEADMPFLANGETVQMILNPLGVPSRMNLGQVLETHLGYAAKTAGIYVKTPVFEGFPESRIWDMMIEQGLPEDGKSYLFDGKTGERFDSKVVVGYIYMLKLSHLIADKIHARSIGPYSLVTQQPLGGKAQMGGQRFGEMEVWALEAYGVAHMLQEILTVKSDDVSGRTRIYESIVKGENLLRSGTPESFNVLIKEMQGLGLDVRPMVVDA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: HIS4_SALG2
Sequence: MIIPALDLIDGTVVRLHQGDYARQRDYGNDPLPRLQDYAAQGAGVLHLVDLTGAKDPAKRQIPLIKTLVAGVNVPVQVGGGVRTEEDVAALLKAGVARVVIGSTAVKSPDVVKGWFERFGAQALVLALDVRIDEHGNKQVAVSGWQENSGVSLEQLVETYLPVGLKHVLCTDISRDGTLAGSNVSLYEEICARYPQIAFQSSGGIGDIDDIAALRGTGVRGVIVGRALLEGKFTVKEAIQCWQNV
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPG_SALDC
Sequence: MHNQAPIQRRKSTRIYVGNVPIGDGAPIAVQSMTNTRTTDVEATVNQIKALERVGADIVRVSVPTMDAAEAFKLIKQQVNVPLVADIHFDYRIALKVAEYGVDCLRINPGNIGNEERIRMVVDCARDKNIPIRIGVNAGSLEKDLQEKYGEPTPQALLESAMRHVDHLDRLNFDQFKVSVKASDVFLAVESYRLLAKQIDQPLHLGITEAGGARSGAVKSAIGLGLLLSEGIGDTLRVSLAADPVEEIKVGFDILKSLRIRARGINFIACPTCSRQEFDVIGTVNALEQRLEDIITPMDVSIIGCVVNGPGEALVSTLGVTGGNKKSGLYEDGVRKDRLDNDDMIAQLESRIRAKASQLDEARRIDVLQVEK
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: PMVK_HUMAN
Sequence: MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFREAYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENLIEFIRSRL
What is the function of this protein?
Catalyzes the reversible ATP-dependent phosphorylation of mevalonate 5-phosphate to produce mevalonate diphosphate and ADP, a key step in the mevalonic acid mediated biosynthesis of isopentenyl diphosphate and other polyisoprenoid metabolites.
What are the official names of this protein?
Phosphomevalonate kinase, PMKase, hPMK.
Protein: DXR_BAUCH
Sequence: MKYLTILGSTGSIGTSTLTVIKQNPDKFTVRALVAKNNFTLMTKQCLDFRPSWVGMVDKRAARELKANLAQLGIAINIISGNQAACELAALKEIDTVMAAIAGVDGLLSTLSALRAGKRVLLANKESLVSCGRLFMNEVHQHNAQLLPVDSEHNAIFQILPEPIQRQLGCLSLSKYGVSQIILTGSGGPFRQTPLDALATITSDQACIHPNWSMGRKISVDSATMMNKGLEYIEARCLFNASTDQIEVLLHPQSIFHSMVRYVDGSVLAQLAYPDMRIPITYALSYPTRVPIKVTPLNFLQLGTLSFDQPDNKRYPCLQLAIEASKLGQAATTTLNAANEVAVAAFLQRKIRFTDIASVNQMVLDKINLEEPSSIEEVLCIDRQARINAHLSIRYLAL
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: RL14_NEIG1
Sequence: MIQMQTILDVADNSGARRVMCIKVLGGSKRRYASVGDIIKVAVKDAVPRGRVKKGDVYNAVVVRTAKGVRRPDGALIKFDNNAAVLLNNKLEPLGTRIFGPVTRELRTERFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: HBE_PITIR
Sequence: MVHFTAEEKAAITSLWGKMNVEEAGGEALGRLLVVYPWTQRFFDNFGNLSSPSAILGNLKVKAHGKKVLTSFGDAIKNMDNLKTTFAKLSELHCDKLHVDPENFRLLGNVMVIILATHFGKEFTPEVQAAWQKLVSAVAIALGHKYH
What is the function of this protein?
The epsilon chain is a beta-type chain of early mammalian embryonic hemoglobin.
What are the official names of this protein?
Hemoglobin subunit epsilon, Epsilon-globin, Hemoglobin epsilon chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: HIS4_PAEAT
Sequence: MTTSAQSVLELLPAVDIVDGQAVRLLQGEAGSETSYGTPLEAALNWQNDGAEWVHMVDLDAAFGRGNNAALISDVVSQLNVKVELSGGLRDDESLERALELGVARVNLGTAALENPEWTRKAIDRFGDKIAVGLDVRGTTLAGRGWTKEGGDLWEVLARLEDAGCARYVVTDVTKDGTLQGPNVELLRQMVEKTGKPVVASGGISSLEDLRVLRELVPLGVEGAIVGKALYAGAFTLPEALDVAGRR
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: K1C15_PROAT
Sequence: LLLLGHASTSTRGFSGNSFKSDLIPQSRRSHSVYGTPGSIRISSPSVPSAIVSSYSSTLSSALPSSSYGGNSFSSSTSFSSGGSDLLLGTSGKEAMQNLNDRLASYLDKVRSLEGKNHELELKIKDWYSQVIPGTGGPDARDYGHLEKEIEDLQNKVNNCRVDTATILLHIDNAKLAADDFRNKYENEQSLRLGVEADINGLKRVLDELALAKADTDMQIEGLRDELDYLKKNHEEDMKAASSGIAGQVNVELDAAPGTNLLDELDACRRDHEAMLDQMRREAERWYNEKAKDVKDKAGEAQETLVSHTSEISDLKRSIQSLEIELQTQLARKSSLESTLAGTESQYGMRIQEIQMKINVFEDQISDLRAKMEFQSQEYQMLLDVKQRLEAEIATYRMLLDSEDSKGSIINHKILTAIEKLVDGIVLSTEVLEKQIPVLSY
What are the official names of this protein?
Keratin, type I cytoskeletal 15, Cytokeratin-15, CK-15, Keratin-15, K15.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: LEPA_FUSNN
Sequence: MEAIMLQKNKRNFSIIAHIDHGKSTIADRLLEYTGTVSERDMKEQILDSMDLEREKGITIKAQAVTLFYKAKNGEEYELNLIDTPGHVDFIYEVSRSLAACEGALLVVDAAQGVEAQTLANVYLAIENNLEILPIINKIDLPAAEPEKVKREIEDIIGLPADDAVLASAKNGIGIEDILEAIVHRIPAPNYDEDAPLKALIFDSYFDDYRGVITYVKVLDGNIKKGDKIKIWSTEKELEVLEAGIFSPTMKSTDILSTGSVGYIITGVKTIHDTRVGDTITSVKNPALFPLAGFKPAQSMVFAGVYPLFTDDYEELREALEKLQLNDASLTFVPETSIALGFGFRCGFLGLLHMEIIVERLRREYNIDLISTTPSVEYKVSIDNQEEKVIDNPCEFPDPGRGKITIQEPYIRGKVIVPKEYVGNVMELCQEKRGIFISMDYLDETRSMLSYELPLAEIVIDFYDKLKSRTKGYASFEYELSEYKISNLVKVDILVSGKPVDAFSFIAHNDNAFHRGKAICQKLSEVIPRQQFEIPIQAALGSKIIARETIKAYRKNVIAKCYGGDITRKKKLLEKQKEGKKRMKSIGNVEIPQEAFVSVLKLND
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS19_MAGMM
Sequence: MARSVKKGPFLDDFLVKKVDVLREGSRKELIKTWSRRSTIIHEFVGYTFGVHNGRKFIPVLVTENMVGHKLGEFAPTRTYYGHGVDKKAKRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.