PharMolix/UniProtQA huggingface dataset:
Protein: U95_HHV6U
Sequence: MSAHPDDLFWQQILNMDPTELLSDDVISSTCDENTAAGTDIMQPLCVDMSVQPTTSGCHTGAMMSDSYFSNDTPDQNCQSHSTLTDLSPEDMNNQINVQPNQMTFQPISPPIQDQNYGYSNNMINPIKPASIIKLHGHSIGEMTVTDPSSHVNAQHFVQQSNPKFFLNMYPCMTANSQGPGECQSVHNQSSGSGSNSYDINTAPRDEWIFTTSGGESWVLKRNTPNPPNSRTNLIFNNAQPIFHTQPQVSGFSDCSYQGGGLNSREYVNLAGYTPVCNMQNIKNSWATQLGASIDCMTASPTGIDANVNSAFQPVGVVSNNRGANVSMGGMGNYIENNSPWNQYYKSEMANNSINVKESNVYGHVGCVNDAISDKQGGTANVPSSLLNPDHQDWMRMTGTNTHMLNNINTNTEMENYDFPENDGNVHGATGVDLSTLSNGQQHSAFEGNGTFPVVNTGNPRTTLNCAPQLFLLGGNPTIAHPMNGNNETPDKNVCKPTPSTGVIKKLNFDGVDRGGGIGNFPKLASFVAMREKMSNTVNPSCGTFLEQLEGLRQQNSFEKNISFADLHFSEEDDVLSSASSVSCNSNCDMKIEVSQQGITVSNLQQGFRQQMNMNSSVVKMDGSYKTQEMSNGCATDVTDNAGTIQQNKRIHSQNENPEDGQVREGGCSDVRNEPPRKSARIHNMKSEGVTCGMCMTAADSTRQDASGGSSSGTKNEYYDDESELTGLSDTDSDNEVQCCQEVTKVGPKTYSSENFNPEYRQAKRLLADIPYRRWIPDPVNMEDNDGPFIPIVTRPATVCMNGRRRRTFFRQCVTAFGPLSKLTYFKELLQSYVSKNNNSYLSISWPPKHGVYVMSEKKLGYEHIPTLKDKFPLPCGWMMVLGVVGAEPPAALNKNMVILLCENRWVLLHNYSNSTHELFLAASDLKQFMEEGLSRCDPIYEESTVPYGVAMENSLRDFLRNSRTFQDLMDQRDNMHGCNWTFNGMPGRLGDRVIHLCNPESVDSIPGDEAVVCEGRPLYFFAYVTTFKSNPATKATVLIAADKDLRIYGYHKGRPRIRYLCKNVKTFFKAGARKFYLDFQITPKRLLAVNEEEYLNTLQNAPCLLLKPSVFRNIYSQEGK
What are the official names of this protein?
Uncharacterized protein U95.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae US22 family.
Protein: RL31_PROM3
Sequence: MPKPDIHPNWYPDAKVICNGEVVMTTGSTQPELHVDVWSGNHPFFTGTQKILDTEGRVDRFMRKYGMGSADAAADEKKTDAKNNNKDNTSKED
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: RL9_COREF
Sequence: MKLILTAAVENLGVAGDIVEVKDGYGRNLLLPRGLAIPATPGAEKQIEGIKRAQEARAIRDLDHAREVKAQLEALEGVKVAVRTSESGKLFGSVKADDIVDAVKAAGGPNLDKRAIVLPKNLVKTTGKYQVEAKIHEGIVSRVKFEVVAA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: DAPF_SHEWM
Sequence: MIHFAKMHGLGNDFMVVDGVTQNVFFSPEQIKRLADRNFGVGFDQLLLVEPPYDPDLDFHYRIFNADGGEVEQCGNGARCFARFVRNKGLTNKHKIKVSTSNGKITLRLERDGNVTVNMGVPVLDPSKIPFNAKRVEKTYLLQTSSSHAMETFLCGAISMGNPHCVLEVEDIEHAEVERIGALLTQNERFPKGVNVGFMQVIDAGHIKLRVYERGAAETLACGTGACAAAAVGQLQGKLNKMVRVDLPGGTLTINWEGEGNPLWMTGPAEHVYDGQIPQ
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NICA_CAEEL
Sequence: MKKWLVIVLIIAGIRCDGFSDQVFRTLFIGEGNACYRTFNKTHEFGCQANRENENGLIVRIDKQEDFKNLDSCWNSFYPKYSGKYWALLPVNLIRRDTISQLKSSKCLSGIVLYNSGESIHPGDESTAASHDAECPNAASDYYLQDKNEEYCERKINSRGAITRDGLMKIDWRIQMVFIDNSTDLEIIEKCYSMFNKPKEDGSSGYPYCGMSFRLANMAAGNSEICYRRGKNDAKLFQMNIDSGDAPQLCGAMHSDNIFAFPTPIPTSPTNETIITSKYMMVTARMDSFGMIPEISVGEVSVLTSIISVLAAARSMGTQIEKWQKASNTSNRNVFFAFFNGESLDYIGSGAAAYQMENGKFPQMIRSDRTHIHPIRPNELDYILEVQQIGVAKGRKYYVHVDGERYQQNKTQTDRVIDRIERGLRSHAFDLEKPSGSGDRVPPASWHSFAKADAHVQSVLLAPYGKEYEYQRVNSILDKNEWTEDEREKAIQEIEAVSTAILAAAADYVGVETDEVVAKVDKKLITTIFDCLITSNFWFDCDFMQKLDGGRYHKLFNSYGFNQKSTYISMESHTAFPTVLHWLTIFALGSDKETLNVKSEKSCSHLGQFQAFQMYTYTWQPNPYTGNFSCLKSAIVKKVMVSPAVDSQTPEEEMNTRYSTWMESVYIIESVNLYLMEDASFEYTMILIAVISALLSIFAVGRCSETTFIVDEGEPAAEGGEPL
What is the function of this protein?
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch (glp-1 or lin-12).  It may represents a stabilizing cofactor required for the assembly of the gamma-secretase complex.
What are the official names of this protein?
Nicastrin, Anterior-pharynx-defective protein 2.
What is the protein family that this protein belongs to?
Belongs to the nicastrin family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: DEF89_ARATH
Sequence: MGFKNNLSLVSVMVFALILLPMISGQTMQCYSGIACTDDGTCNDYCNPRNNNLGGVCLRRANCCCCYVSVVKSQESSLSKDTNNVFITN
What are the official names of this protein?
Putative defensin-like protein 89.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS4_METKA
Sequence: MGDPKRPRKKYETPRHPWEAERLEYERKLMRKYGLRRKKELWRHQTQLKRWRERAKELMARTDPEAQREREALFRKLYDLGILDKKPEEATLDDILRLTVEDVLERRLQTIVYRKGLAKTPLQARQLVVHRHIAIGDRIVTVPSYLVSREEEEEVDYSPYSPLKDEDHPIRCEARGESPEETAAEE
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: QUEA_BURMS
Sequence: MLTLSDFDFDLPPELIAQTALPERSASRLLEVDNTNPSAPPRLIDRRFAELPACVAPGDLLVFNDTKVLKARFFGRKASGGKIEVLIERVTGERTALAQIRASKSPPPGTTLTLADAFDVTVGERVEPFFTLHFPDNCLVLIERHGRLPLPPYIEHAPDAADETRYQTVFAANPGAVAAPTAGLHFDDAVLAALEARGVERATLTLHVGAGTFQPVRVENLAEHRMHSESYELTDALVEKIAATRARGGRVIAVGTTSMRALEAAARDAQAAGRPLAATRAETDIFITPGYRFRVVDRLVTNFHLPKSTLLMLVSAFAGIETIRAAYRHAIDARYRFFSYGDAMLLTRRDDAAEATHGGA
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TILS_PROMA
Sequence: MTNSTKVEKPWTKWHERLHKSLKSKSNLLPYGSSLLISVSGGQDSMALLKLILDLQRIYEWKVHVWHGDHGWHNQSRQIAEELEEWCKCQKLSFFCNRTNKQKVSTEEDARNWRYKSLIQQAKTLSKESPSLPCERVLTGHTANDRTETFIMNLARGAHLKGLSSLREDRTLETKIQLIRPILRFSRQETIQICDEMDLPIWIDPSNSNIAYSRNKIRAEIIPVLESLHPQSTIRISNLAERLTSLQKDQHQLAHLALGALLTSTGLSRSKMTKLSKTVRAIILAQWLEDNKAPLLSSKQLEELSQKIGKNKGPGNMDISNHLKIRWNKNSIELIN
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNC_RHIEC
Sequence: MSKAQTLSAADRAKLEALIGHDFAEKERLDRALTHASARTEKGSNYERLEFLGDRVLGLCIAELLFRTFGTAGEGELSVRLNQLVSAETCAAVADELNLHLYIRTGADVKKLTGKRMMNVRADVVESLIAAIYLDGGLEVARRFILRYWQGRAVRADGAKRDAKTELQEWSHAKFGVTPIYRVDERSGPDHDPRFRVTVEVAGIKPESGVERSKRAAEQVAATKMLEREGIWQQSPAGN
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_ECO55
Sequence: MTAIAPVITIDGPSGAGKGTLCKAMAEALQWHLLDSGAIYRVLALAALHHHVDVASEDALVPLASHLDVRFVSTNGNLEVILEGEDVSGEIRTQEVANAASQVAAFPRVREALLRRQRAFRELPGLIADGRDMGTVVFPDAPVKIFLDASSEERAHRRMLQLQEKGFSVNFERLLAEIKERDDRDRNRAVAPLVPAADALVLDSTTLSIEQVIEKALQYARQKLALA
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_CYTH3
Sequence: MKKIIVAIDGYSACGKSTTAKILAAKLGYVYIDTGAMYRSVALYFIQHYINSTNPKAVAEALNQIHISFVHNNKTETCETYLNGLNVESEIRKMYVSEKVSEVSAIPEVRKRMVELQQKMARKRGVVMDGRDIGTHVFPDAELKIFMVADMHVRAFRRQQELFERKQIIDLDDIIKNIESRDLMDTTREESPLRKASDAYEIDTTYITVEEQVDCIMNIAVGKMIELEYNIENI
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH10_NITEU
Sequence: MNIRPLHDRVIVKRLEEERKTASGIVIPDTAAEKPDQGEIIAVGKGKTGEDGKIRALEVKVGDRVLFGKYAGQAVKIKGEEFLVMREEDIMGVIEG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMJ_SHISS
Sequence: MKICLIDETGAGDGALSVLAARWGLEHDEDNLMALVLTPEHLELRKRDEPKLGGIFVDFVGGAMAHRRKFGGGRGEAVAKAVGIKGDYLPDVVDATAGLGRDAFVLASVGCRVRMLERNPVVAALLDDGLARGYADAEIGGWLQERLQLIHASSLTALTDITPRPQVVYLDPMFPHKQKSALVKKEMRVFQSLVGPDLDADGLLEPARLLATKRVVVKRPDYAPPLANVATPNAVVTKGHRFDIYAGTPV
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPE_MYCTU
Sequence: MAGSTGGPLIAPSILAADFARLADEAAAVNGADWLHVDVMDGHFVPNLTIGLPVVESLLAVTDIPMDCHLMIDNPDRWAPPYAEAGAYNVTFHAEATDNPVGVARDIRAAGAKAGISVKPGTPLEPYLDILPHFDTLLVMSVEPGFGGQRFIPEVLSKVRAVRKMVDAGELTILVEIDGGINDDTIEQAAEAGVDCFVAGSAVYGADDPAAAVAALRRQAGAASLHLSL
What is the function of this protein?
Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
What are the official names of this protein?
Ribulose-phosphate 3-epimerase.
What is the protein family that this protein belongs to?
Belongs to the ribulose-phosphate 3-epimerase family.
Protein: OBG_STRCO
Sequence: MTTFVDRVELHVAAGNGGHGCASVHREKFKPLGGPDGGNGGRGGDVILTVDQSVTTLLDYHHSPHRKATNGKPGEGGNRSGKDGQDLVLPVPDGTVVLDGAGNVLADLVGHGTSYVAAQGGRGGLGNAALASARRKAPGFALLGEPGDLQDIHLELKTVADVALVGYPSAGKSSLISVLSAAKPKIADYPFTTLVPNLGVVTAGETVYTVADVPGLIPGASQGKGLGLEFLRHVERCSVLVHVLDTATLESERDPLSDLDVIETELREYGGLDNRPRIVVLNKIDVPDGKDLAEMVRPDLEARGYRVFEVSAVAHMGLRELSFALAELVATARAARPKEEATRIVIRPKAVDDAGFTVTREEDGLFRVRGEKPERWVRQTDFNNDEAVGYLSDRLNRLGVEDKLMKAGARNGDGVAIGPEDNAVVFDWEPSVTAGAEMLGRRGEDHRFEAPRPAAQRRRDRDAERDEAQQEFDGFEPF
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein. Note=No longer associated with the cell membrane after salt-washing.
Protein: NR1I2_RAT
Sequence: MRPEERWNHVGLVQREEADSVLEEPINVDEEDGGLQICRVCGDKANGYHFNVMTCEGCKGFFRRAMKRNVRLRCPFRKGTCEITRKTRRQCQACRLRKCLESGMKKEMIMSDAAVEQRRALIKRKKREKIEAPPPGGQGLTEEQQALIQELMDAQMQTFDTTFSHFKDFRLPAVFHSDCELPEVLQASLLEDPATWSQIMKDSVPMKISVQLRGEDGSIWNYQPPSKSDGKEIIPLLPHLADVSTYMFKGVINFAKVISHFRELPIEDQISLLKGATFEMCILRFNTMFDTETGTWECGRLAYCFEDPNGGFQKLLLDPLMKFHCMLKKLQLREEEYVLMQAISLFSPDRPGVVQRSVVDQLQERFALTLKAYIECSRPYPAHRFLFLKIMAVLTELRSINAQQTQQLLRIQDTHPFATPLMQELFSSTDG
What is the function of this protein?
Nuclear receptor that binds and is activated by a variety of endogenous and xenobiotic compounds.  Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, endogenous compounds and drugs.  Response to specific ligands is species-specific, due to differences in the ligand-binding domain.  Activated by naturally occurring steroids, such as pregnenolone and progesterone.  Binds to a response element in the promoters of the CYP3A4 and ABCB1/MDR1 genes (By similarity).
What are the official names of this protein?
Nuclear receptor subfamily 1 group I member 2, Orphan nuclear receptor PXR, Pregnane X receptor.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: THIE_SALTO
Sequence: MSSLGRLHLITDARAGRNPLTVVQAALSVARTELVVQVRVADDATDRQAYDLARRVIALCARYDATCLVNDRLHVALAVGAAGGHVGADDLPVGAARAVLGSAAVLGVTARDADTAVEAVAAGASYLGVGPVHPTTSKEGLPPAIGVAGVGVVAAAVSVPVIAIGAVTAADVPVLRAAGAYGVAVIGALSHAADPAGATAALLEALTW
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: ENOPH_DANRE
Sequence: MAAIAIPENTRVFLLDIEGTTTPITFVKDILFPYIRENLEDYLSAHWEEDECKQDVHLLKKQTEEDLRQNKACHVHTVDQTVHTDEEKAIREVVENVLWQMAADRKTTALKQLQGHMWRAAYMMGRIKGEVYQDVVPAIRRWRHHGLKIYIYSSGSVEAQKLLFGYSVQGDILDLFDGHFDTNIGAKVESKSYENIAERIGCQPEEIMFLTDVTREAKAAEDAGVNVAVVVRPGNMELTEEERDHYRIITSFNQLELIGNV
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase, MASA homolog.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MYBB_XENLA
Sequence: MSRRSRGDDLEDLQYQDTDSDVPEPKENRVKVKWTPEEDETLKALVKKHGQGEWKTIASNLNNRTEQQCQHRWLRVLHPDLVKGPWTKEEDEKVIELVKKYGTKHWTLIAKQLRGRMGKQCRERWHNHLNPEVKKSSWTEEEDRIICQAHKVLGNRWAEIAKLLPGRTDNAVKNHWNSTIKRKVETGGFLTVKASGQQEEREDSGYQAAEDQNHVLLSEPVERSANIPEEPSNILSPKLLTKSPGIRSEQESGGEGSNSESATAIVDSAPEKWMVEYVNFLVPGSDIMESDPEAWCELSSFDLGEDSTVSDVGSPTHAAVTDKPQASNVTEYRLDGHTLSDLCKGNKGELIPISPQPQTAFGTPPSVLKQHKKRKITLSPVTENGGSITTSVTEANSMTPKSTPVKSLPFSPSQFLNFWSKQDALELENPSLTSTPVCSQKTMVTTPLHRDKTPLLQKNSVFITPNNKFAADHVLHTPTPFKNALEKFGSLKPLPPTPHLEEDLKEVLRSESGIELIIVDEPKLERQKRKPHSPMKKVRKSLALDIIDKHPKPSSLTLPSAVSAHMQPQTCDSFLSVSLNESSCSREENSVLNQGFVQVKTSKGAVVQLGNTSQLLTDIGELVKTQCSLRNTETATPFKTENGTFTNTDLCPQSLMDLDTFHSTAVASNKCPTIKTETLFQVKPEKTKMQRHNIMNIPEPMTAAWKTVAFGGSQDQMLMQEKARAILNLTYKHSSTSRALVLS
What are the official names of this protein?
Myb-related protein B, B-Myb, Myb-like protein 2, Myb-related protein 1, XMYB1.
What are the subcellular locations of this protein?
Nucleus.
Protein: RK22_NICTO
Sequence: MLKKKKTEVYALGEHISMSADKARRVIDQIRGRSYEETLMILELMPYRACYPILKLVYSAAANASYNMGSSEANLVISKAEVNGGTTVKKLKPRARGRSFPIKRSTCHITIVMKDISLDDEYVEMYSLKKTRWKKKPTAMPYRDMYNSGGLWDKK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SLAF7_HUMAN
Sequence: MAGSPTCLTLIYILWQLTGSAASGPVKELVGSVGGAVTFPLKSKVKQVDSIVWTFNTTPLVTIQPEGGTIIVTQNRNRERVDFPDGGYSLKLSKLKKNDSGIYYVGIYSSSLQQPSTQEYVLHVYEHLSKPKVTMGLQSNKNGTCVTNLTCCMEHGEEDVIYTWKALGQAANESHNGSILPISWRWGESDMTFICVARNPVSRNFSSPILARKLCEGAADDPDSSMVLLCLLLVPLLLSLFVLGLFLWFLKRERQEEYIEEKKRVDICRETPNICPHSGENTEYDTIPHTNRTILKEDPANTVYSTVEIPKKMENPHSLLTMPDTPRLFAYENVI
What is the function of this protein?
Isoform 3 does not mediate any NK cell activation.
What are the official names of this protein?
SLAM family member 7, CD2 subset 1, CD2-like receptor-activating cytotoxic cells, CRACC, Membrane protein FOAP-12, Novel Ly9, Protein 19A.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: YBHG_SALTI
Sequence: MKKPVVIGLVIAAIVAVIAGGTWWYQSRQDDGLTLYGNVDIRTVNISFRVGGRLASLNVDEGDTIKAGQVLGELDHAPYENALMQAKAGVSVAQAQYDLMLAGYRDEEIAQAAAAVRQAQAAYDYAQNFYNRQQGLWKSRTISANDLENARSSRDQAQATLKSAQDKLSQYRTGNREQDIAQAKASLEQAKAQLAQAQLDLQDTTLIAPANGTLLTRAVEPGSMLNAGSTVLTLSLTRPVWVRAYVDERNLSQTQPGRDILLYTDGRPDKPYHGKIGFVSPTAEFTPKTVETPDLRTDLVYRLRIIVTDADDALRQGMPVTVKFNDEARHE
What are the official names of this protein?
UPF0194 membrane protein YbhG.
What is the protein family that this protein belongs to?
Belongs to the UPF0194 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: NFRA_STAAN
Sequence: MSDYVYNLVKKHHSVRKFKNKPLSEDVVKKLVEAGQSASTSSFLQAYSIIGIDDEKIKENLREVSGQPYVVENGYLFVFVIDYYRHHLVDQHAETDMENAYGSTEGLLVGAIDAALVAENIAVTAEDMGYGIVFLGSLRNDVERVREILDLPDYVFPVFGMAVGEPADDENGAAKPRLPFDHVFHHNKYHADKETQYAQMADYDQTISEYYDQRTNGNRKETWSQQIEMFLGNKARLDMLEQLQKSGLIQR
What is the function of this protein?
Reduces FMN, organic nitro compounds and disulfide DTNB.  Involved in maintenance of the cellular redox state and the disulfide stress response (By similarity).
What are the official names of this protein?
NADPH-dependent oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the flavin oxidoreductase frp family.
Protein: BECN1_PONAB
Sequence: MEGSKTSNNSTMQVSFVCQRCSQPLKLDTSFKILDRVTIQELTAPLLTTAQAKPGETQEEETNSGEEPFIETPRQDGVSRRFIPPARMMSTESANSFTLIGEASDGGTMENLSRRLKVTGDLFDIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQMQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEWNEINAAWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYLESLTDKSKELPLYCSGGLRFFWDNKFDHAMVAFLDCVQQFKEEVEKGETRFCLPYRMDVEKGKIEDTGGSGGSYSIKTQFNSEEQWTKALKFMLTNLKWGLAWVSSQFYNK
What is the function of this protein?
Beclin-1-C 35 kDa localized to mitochondria can promote apoptosis; it induces the mitochondrial translocation of BAX and the release of proapoptotic factors.
What are the official names of this protein?
Beclin-1.
What is the protein family that this protein belongs to?
Belongs to the beclin family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein. Mitochondrion membrane; Peripheral membrane protein. Cytoplasmic vesicle, autophagosome. Note=Interaction with ATG14 promotes translocation to autophagosomes. Expressed in dendrites and cell bodies of cerebellar Purkinje cells. SUBCELLULAR LOCATION: [Beclin-1-C 35 kDa]: Mitochondrion. Nucleus. Cytoplasm. SUBCELLULAR LOCATION: [Beclin-1-C 37 kDa]: Mitochondrion.
Protein: Y3126_MYCTO
Sequence: MVIRFDQIGSLVLSMKSLASLSFQRCLRENSSLVAALDRLDAAVDELSALSFDALTTPERDRARRDRDHHPWSRSRSQLSPRMAHGAVHQCQWPKAVWAVIDNP
What are the official names of this protein?
Uncharacterized protein MT3211.
Protein: RISB_LEPCP
Sequence: MKNADRGVAAELDGSDLRVAIVQARFNAAITEQLASSCIAELEALGVLAKHIKHVTVPGALEVALALQALAEQKDHDALIALGCIIRGETYHFELVANESGAAVTRVSLEHGVPIANAILTVENEAQAWARADEKGRDAARVAVEMANLMEDLS
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: ACLB_ASPOR
Sequence: MASESSIPLYDCLIIGGGIAGLSSALSLVRTLHTAVVFDEGIHRNDQAPHLATVPTWDSQDPKRFRDAAKLNILSKYSTVEFANVKLEKFNKALGKPFLTKVFGHDYVVLPSKYFDDIKRASPQSLSFFQALSDGLNMEASVGHLYASTTEIDVVVKHLNPRLTQLTPLLCDEAEYAIEREVGALPDWKKFNVSNLIAAIVHRTTNRILVGKELCRNEEYLAITTKFSRSLFISGIFWNFVRLGPLRKLVAWLTIGLHLRDRNAAAKVLLPHVLARRQEKEAGVDVATKYPDALQWTIDTAPSFPGDDEPLHQVYHMLHLTFAASSASGVGVTQCLLNVLAYPEYLEPLRDEISTVVARHGGWTDKALSQMALLDSFIRETMRLHPAGSFMDDHFRFHDGLTLPKGTNIIAPALAIHYDPDNYEDAHRFDGFRFARYRQKQGENHRWLASTIDQKFLQFGYGNHACPGRFYAIRKIKLVLAKLIMDYDFKWAQPRPVHDRPEDFAIEAQLVAAPDAEILIRSRNLSN
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of aspirochlorine (or antibiotic A30641), an unusual halogenated spiro compound with distinctive antifungal properties due to selective inhibition of protein biosynthesis, and which is also active against bacteria, viruses, and murine tumor cells (PubMed:25302411).  The non-ribosomal peptide synthetase (NRPS) aclP is responsible the formation of the diketopiperazine (DKP) core from the condensation of 2 phenylalanine residues (PubMed:25302411).  One Phe residue is tailored into chlorotyrosine by hydroxylation and chlorination, whereas the second Phe undergoes an unprecedented C-C bond cleavage to be converted into glycine (PubMed:25302411).  After formation of the DKP, sulfur is incorporated into the DKP by conjugation with glutathione by aclG, followed by its stepwise degradation to the thiol by aclI, aclJ and aclK, and the dithiol oxidation by aclT (PubMed:25302411).  In addition, oxygenases (aclB, aclC, aclL and aclO) and O-methyltransferases (aclM and aclU) act as tailoring enzymes to produce the intermediate dechloroaspirochlorine (PubMed:25302411).  Ultimately, chlorination of dechloroaspirochlorine by the halogenase aclH is the last step in the aspirochlorine pathway (PubMed:25302411).
What are the official names of this protein?
Cytochrome P450 monooxygenase aclB, Aspirochlorine biosynthesis protein B.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: PSTB1_STRPB
Sequence: MMTESILQIRDLSVYYNQKKTLKDVSLDLYPNEITALIGPSGSGKSTLLRSINRMNDLNPEVTITGSIVYNGHNIYSPRTDTVDLRKEIGMVFQQPNPFPMSIYENVVYGLRLKGIRDKSILDHAVESSLKGASIWNEVKDRLHDSAVGLSGGQQQRVCIARVLATSPRIILLDEPTSALDPISAGKIEETLLLLKKDYTLAIVTRSMQQASRLSDRTGFFLEGDLLECGPTKAMFMNPKRKETEDYISGKFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB 1, ABC phosphate transporter 1, Phosphate-transporting ATPase 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.