PharMolix/UniProtQA huggingface dataset:
Protein: CBPC6_MOUSE
Sequence: MAERSQTAPEAGNDTGNEDAIGGNVNKYIVLPNGYSGQPKKGHLTFDACFESGNLGRVEQVSDFEYDLFIRPDTCNPRFRVWFNFTVENVKELQRVIFNIVNFSKTKSLYRDGMAPMVKSTSRPKWQRLPPKNVYYYRCPDHRKNYVMSFAFCFDREDDIYQFAYCYPYTYTRFQHYLDSLQKKNMDYFFREQLGQSVQQRQLDLLTITSPENLREGSEKKVIFITGRVHPGETPSSFVCQGIIDFLVSQHPIARVLREHLVFKIAPMLNPDGVYLGNYRCSLMGFDLNRHWLDPSPWAHPTLHGVKQLIIKMYNDPKTSLEFYIDIHAHSTMMNGFMYGNIFEDEERFQRQSIFPKLLCQNAEDFSYTSTSFNRDAVKAGTGRRFLGGLLDHSSYCYTLEVSFYSYIIGGTTAAVPYTEEAYMKLGRNVARTFLDYYRLNSLVEKIAVPMPRLRSKEERRLGWEHPSCLRAEQPLEVLGIPMCSGKALNEHLGNDIQWHLDCGSSTLPLGLISCSPSSSASWNDMAMSNSILLPDHSFH
What is the function of this protein?
Metallocarboxypeptidase that mediates protein deglutamylation of tubulin and non-tubulin target proteins (PubMed:21074048, PubMed:25103237, PubMed:26829768, PubMed:29593216).  Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of tubulin protein (PubMed:21074048, PubMed:25103237).  Specifically cleaves tubulin long-side-chains, while it is not able to remove the branching point glutamate (PubMed:25103237).  Also catalyzes the removal of polyglutamate residues from the carboxy-terminus of non-tubulin proteins such as MYLK (PubMed:21074048).  Mediates the deglutamylation of nucleotidyltransferase CGAS, leading to CGAS antiviral defense response activation (PubMed:26829768).  Involved in KLF4 deglutamylation which promotes KLF4 proteasome-mediated degradation, thereby negatively regulating cell pluripotency maintenance and embryogenesis (PubMed:29593216).
What are the official names of this protein?
Cytosolic carboxypeptidase 6, ATP/GTP-binding protein-like 4, Protein deglutamylase CCP6.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Golgi apparatus. Cytoplasm, cytoskeleton, cilium basal body. Note=Colocalizes with gamma- tubulin in the centrioles at interphase and dividing cells and with glutamylated tubulin in basal bodies of ciliated cells.
Protein: ISPF_SHEB8
Sequence: MKIRIGHGFDVHKFGAARPLILCGVEVPYETGLIAHSDGDVVLHAISDAILGALALGDIGKHFPDTDTAYKGADSRVLLRHCYALARAKGFVLGNLDVTIIAQAPKMAPHIEAMRQILAADLTSELDDINVKATTTEQLGFTGRKEGIAVEAVVLMTRKHD
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: HIS2_HALMA
Sequence: MSDDTGDVIDELFAVIEDRKANLPEDSYTASLFTHEKGENAVLEKLGEETTELILAAKDDDTEELAHESADIVYHLLVLLSMKEMDIDDLRAELAKRR
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBS3A_MOUSE
Sequence: MAAGETQLYAKVSNKLKGRSTPSLLDPLLAMGFPTHTALKALAATGRKTAEAAADWLHGHCNDPSLDDPIPQEYALFLCPTGPLLEKLQEFWRESRRQCAKNRAHEVFPHVTLCDFFTCEDQKVECLYEALRRAGDRILGSFPTLVPLVLHSSISYLGFFINDSPADAIREFAMAFATEAAVLADCTIKPCTKQLHLTLAHKFYPHHQRTLEQLAKAIQPSHSCQWTAALYSRDMRFVHYQTLKALFQYKPQNADELMLSAGDYIFVDPTQQEEASEGWAIGISHRTGCRGFLPENYTERANEADTWVKHRTYTFNLAMDLNSRKDFEASCRGNGEPHTPSMSKSVSSIQALQATISRRGILVVRHGERVDQVFGKSWLQQCTTADGKYYRPDLNFPRSLPRRSNGIKDFENDPPLSSCGIFQARLAGEALLDSGVRVTAVFASPALRCVQTAKHILEELKLEKKLKIRVEPGIFEWMKWEASKATLTFLTLEELKEANFNVDLDYRPALPRCSLMPAESYDQYVERCAVSMGQIINTCPQDMGITLIVSHSSALDSCTRPLLGLPPRECGDFAQLVRKIPSLGMCFCEENREDGKWDLVNPPVKTLTHGANSVFNWRNWISSN
What is the function of this protein?
Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases.  Promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface.  May inhibit dynamin-dependent endocytic pathways by functionally sequestering dynamin via its SH3 domain (By similarity).  Exhibits negligigle protein tyrosine phosphatase activity at neutral pH.  May act as a dominant-negative regulator of UBASH3B-dependent dephosphorylation.
What are the official names of this protein?
Ubiquitin-associated and SH3 domain-containing protein A, Suppressor of T-cell receptor signaling 2, STS-2, T-cell ubiquitin ligand 1, TULA-1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TIG_STAS1
Sequence: MTATWEKKEGNEGVLSVTVPAEKVDKAIDQAFKKVVKQINVPGFRKGKVPRPIFEQRFGVEALYQDAVDILLPEAYGEAIDETGIKPVDQPEINVTSIEKGKEMTFEANVVVEPEVQLGDYKGLEVEKQDVELTDEELQESIDHQLGHLAEMVVKEDGAIENGDTVNIDFDGYVDGEQFEGGQAEGYDLEIGSGSFIPGFEEQLVGVKTGEEKDVNVTFPEEYHAEELAGKEATFKTKVNEIKYKDVPELTDEIANELDSEANTVDEYKENLRKRLTEQKETDAENNQKEEAINKAANNASIDVPDAMINTELDRMVQEFGQRMQQQGLNLETYFQISGQDESQLREQMKDDAEERVKTNLTLTAIADAEDIEVSDDDIDKELEKMSEQFNISVEDIKQTLGNTDIVKNDVRIQKVIDLLVDEAKLVEPSKDDSEA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: DNAJ_BACC2
Sequence: MSKRDYYEVLGLSKGASTDEIKKAYRRLAKKYHPDVSKEENAIEKFKEVQEAYEVLSDDQKRAQYDQFGHAGANQGFGGFGGGGDFGGGFGFEDIFSSFFGGGGGRRRDPNAPRQGADLQYQVTLDFEEAIFGKELNVEIPVEDPCDTCKGSGAKPGTSKETCKHCSGSGQVSVEQNTPFGRIVNRQACGHCSGTGQIIKEKCTTCHGSGKVRKRKKINVKIPAGIDNGQQIRVSGKGEAGVNGGPAGDLYVVVHVRNHEFFEREGDHIICEMPLTFAQMALGDEVEVPTVHGKVKLKIPAGTQTGTEFRLKGKGAPNVRGYGQGDQYVVVRVVVPTKLTSQQKDLLREFAGQEEQDDSLFGKLKRAFKGE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGB_SYNC1
Sequence: MEELIRKANVLMEALPYIQRFNNKTIVIKYGGHAMVDGRLKHEFARDVVLLKYIGLNPVIVHGGGPQIGQVLKSMGKESRFVQGMRVTDQETMDVAEMVLGGKVNKEIVANINRHDGKAVGLSGKDGRLILARKLEMTAINPDTLTPEIVDVGLVGDVESINTEVITALENNGFIPVIAPIGAGLAGETYNINADIVAGRIAGALRAEKLILLTDVEGVKDKQGKLISTIDTQRVPDLINNGTITGGMIPKLNCCIDALDEGVHTAHIIDGRVEHACLLEIFTDRGVGTAVGRFTS
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPT1C_MOUSE
Sequence: MAEAHQASSLLSSLSSDGAEVELSSPVWQEIYLCALRSWKRHLWRVWNDFLAGVVPATPLSWLFLFSTIQLACLLQLDPSLGLMEKIKELLPDWGGQHHQLQGFLSAAVFASCLWGALIFTLHVALRLLLSHHGWLLEPHGAMSSPTKTWLALVRIFSGRHPRLFSFQRALPRQPVPSAQETVRKYLESVRPVLGDDAFDRATALANDFLRLHAPRLQLYLQLKSWCTSNYVSDWWEEFVYLRSRGSLINSTYYMMDFLYVTPTPLQAARAGNAVHTLLLYRHLLNRQEISPTLLMGMRPLCSAQYERMFNTTRIPGVEKDHLRHLQDSRHVAVFHRGRFFRVGTHSPNGLLSPRALEQQFQDILDDPSPACPLEEHLAALTAAPRSMWAQVRESVKTHAATALEAVEGAAFFVSLDSEPAGLTREDPAASLDAYAHALLAGRGHDRWFDKSFTLIVFSNGKLGLSVEHSWADCPVSGHLWEFTLATECFQLGYATDGHCKGHPDPTLPQPQRLQWDLPEQIQPSISLALRGAKTLSGNIDCHVFPFSHFGKSFIKCCHVSSDSFIQLVLQLAHFRDRGQFCLTYESAMTRLFLEGRTETVRSCTREACQFVRAMDNKETDQHCLALFRVAVDKHQALLKAAMSGQGIDRHLFALYIMSRLLHMQSPFLTQVQSQQWLLSTSQVPVQQTHLIDVHNYPDYVSSGGGFGPAHDHGYGISYIFMGENAITFHISSKKSSTETDSHRLGQHIENALLDVASLFRVGQHFKRQFRGENSDYRYNFLSCKTVDPNTPTSSTNL
What is the function of this protein?
May play a role in lipid metabolic process.
What are the official names of this protein?
Carnitine O-palmitoyltransferase 1, brain isoform, CPT1-B, CPT IC, Carnitine O-palmitoyltransferase I, brain isoform, CPTI-B, Carnitine palmitoyltransferase 1C.
What is the protein family that this protein belongs to?
Belongs to the carnitine/choline acetyltransferase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Synapse. Cell projection, axon. Cell projection, dendrite. Endoplasmic reticulum. Note=Localized in the soma and dendritic and axonal projections.
Protein: CH603_FRACC
Sequence: MAKDLRFNVEARRLLEAGVNALADAVKVTLGPKGRNAVIEKLTGPPTITNDGVTIAREIQLRNPFANMGAQLVKEVATKTNGTAGDGTTTATVLAQALVREGLHAVDGGANPMFLKNGIEAAVAALLEEFEKYRGEVEGEADLARVATLAANNDARIGDVVAAALGRVGCDGVVTVEESPIFGLEVSFVDGIELDNGYLSPYMVTDTERMEAAYTDPYILLTNEKISQVQTLMPVLELVTRAGGQLIVFAENVEGPALGMLVANNVHGTFRSAVVRAPGFGHRRLAELNDLAVFLGGQVITADAGLSLDRVTLGQLGRCKKATITEHATTIVDGAGSATEIHARIDQLKRELERAENPHDQDTLQTRIARLSGGVAVIRVGAVTGVELKEKLHRVEDSLAAARAALAEGVVAGGGTALLQAASALDKLTLTGDAAEGREIVRRAIAEPLRWIAINAGYDGDEVVKRVAELPRGHGFNAATGEYGEMAGFGVIDPVKVTRCALQSAASIAALLLTTETLVVEEVIGNPGAVIAPGFGDLAEGLVRPSNIA
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 3, 60 kDa chaperonin 3, Chaperonin-60 3, Cpn60 3.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPG_HALVD
Sequence: MIRLVVVDNFDSFTYNLVEYFSEQTVEGEPLDIEVRKNTASLDEIRDLDPDAIVISPGPGHPKNDRDVGVTNDVLTELSTEIPTLGVCLGLEAAVYAYGGTIGHAPEPIHGKAFPVDHDGAGVFAGLEDGFPAGRYHSLVATDVPDCFDVSATTDHDGEALVMGVRHRDYPIECVQFHPESVLTGSGHGVVRNFLTAVAGFDVA
What is the function of this protein?
Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan.  In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate.  In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia (By similarity).
What are the official names of this protein?
Anthranilate synthase component 2, AS, ASII, Anthranilate synthase, GATase component, Anthranilate synthase, glutamine amidotransferase component.
Protein: PNCB_POLSJ
Sequence: MIITSLLDTDLYKFTMMQVVLHQFPGAEVEYRFKCRNAGAPGIGKLAPYVNEIREEIRGLCNLRFQDAELAYLKAMRFIKSDFVDFLGIFKLNEKYVSVTALPSGEIEVSIKGPWLHTILFEIPVLAIINEVYFRNTQKQPDLTEGRKRLDTKILELQADGLRELKIADYGTRRRFGKVWHEEVLRTLVTRLGTGMSGQLAGTSNVLFAMKLGLTPLGTMAHEYLQACQALGPRLRDSQVFGFESWAREYRGDLGIALSDVYGMSAFLRDFDMYFCKLFDGARHDSGDPFEWGERMLAHYVKNRVDPRTKTLIFSDALTVPRTIELYQQFRGRCQLAFGIGTNLTNDLGYEPLQIVIKMIRCNGQPVAKLSDTPSKNMCEDEKYLAYLRQVFEIG
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: LIGD_PSEAE
Sequence: MPSSKPLAEYARKRDFRQTPEPSGRKPRKDSTGLLRYCVQKHDASRLHYDFRLELDGTLKSWAVPKGPCLDPAVKRLAVQVEDHPLDYADFEGSIPQGHYGAGDVIVWDRGAWTPLDDPREGLEKGHLSFALDGEKLSGRWHLIRTNLRGKQSQWFLVKAKDGEARSLDRFDVLKERPDSVLSERTLLPRHGEAATPAARPARRGKSGGKTPMPEWIAPELASLVEQPPRGEWAYELKLDGYRLMSRIEDGHVRLLTRNGHDWTERLPHLEKALAGLGLQRSWLDGELVVLDEEGRPDFQALQNAFEEGRGENILYVLFDLPYHEGEDLRDVALEERRARLEALLEGRDEDPLRFSATLAEDPRDLLASACKLGLEGVIGKRLGSAYRSRRSNDWIKLKCQLRQEFVIVGYTEPKGSRRHIGALLLGLYSPDEERRLRYAGKVGSGFTAASLKKVRERLEPLAVRSSPLAKVPPARETGSVQWVRPQQLCEVSYAQMTRGGIIRQAVFHGLREDKPAREVTGERPAGPPPLRGARKASAGASRAATAGVRISHPQRLIDPSIQASKLELAEFHARYADLLLRDLRERPVSLVRGPDGIGGELFFQKHAARLKIPGIVQLDPALDPGHPPLLQIRSAEALVGAVQMGSIEFHTWNASLANLERPDRFVLDLDPDPALPWKRMLEATQLSLTLLDELGLRAFLKTSGGKGMHLLVPLERRHGWDEVKDFAQAISQHLARLMPERFSAVSGPRNRVGKIFVDYLRNSRGASTVAAYSVRAREGLPVSVPVFREELDSLQGANQWNLRSLPQRLDELAGDDPWADYAGTRQRISAAMRRQLGRG
What is the function of this protein?
The preference of the polymerase domain for rNTPs over dNTPs may be advantageous in quiescent cells where the dNTP pool may be limiting.
What are the official names of this protein?
Multifunctional non-homologous end joining protein LigD, NHEJ DNA polymerase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the LigD polymerase family.
Protein: YCF39_CYAPA
Sequence: MSILVIGATGTLGRQIVRSALDEGYQVRCLVRNLRKAAFLKEWGAKLIWGDLSQPESLLPALTGIRVIIDTSTSRPTDPAGVYQVDLKGKKALIDAAKAMKIEKFIFFSILNSEKYSQVPLMRIKTVTEELLKESGLNYTIFKLCGFFQGLIGQYAVPILDQQTVWITTESTSIAYMDTIDIARFTLRSLVLKETNNRVFPLVGTRSWNSADIIQLCERLSGQNAKVTRVPIAFLELARNTSCFFEWGWNIADRLAFTEVLSKSQFFNSSMDEVYKIFKIESTSTTILESYLQEYFSRILKRLKEINSQQSQKKKTSDLFV
What are the official names of this protein?
Uncharacterized protein ycf39.
What is the protein family that this protein belongs to?
Belongs to the NmrA-type oxidoreductase family. Ycf39 subfamily.
What are the subcellular locations of this protein?
Plastid, cyanelle.
Protein: NAG3_CELFI
Sequence: MIDLTAAPFSLDDDGIAWVRTTLAEMGEDEKLGQLFCLITYTSDPEYLGYLTRGLHVGGVMLRTMTAADAAATVTTLQSTATVPLLISANLEGGASQTVQEATHVGSNMALAATGSTDHVRRAATVIGREARALGINWAFTPVVDIDLNFRNPITNTRTFGADAATVAAMGAEYVEAIQAQGLAASAKHFPGDGVDERDQHLLASVNTMSVEEWDDSFGVVYRAAIAAGVKTVMVGHIMLPAYSRALRPGVADRDILPGVVAEELLNDLLRDRLGFNGLVVSDSTTMAGLASVLPRSQAVPRVIAAGCDMFLFTKNLDEDFGYMRAGIRDGVITPERLDEAVTRILALKASLGLHRGTNLPAQGAAGVLADPDHSATAREVAASSITLVKEEPGVLPITRERYPRVLVYDLQNGGSPIGQGARAGAVEQFVDALVEAGHDVTRFEPGGGWEGMAAPTTDVTERHDLVLYLANLSTRSNQTVVRIEWAEPMGANVPAYVHSVPTVFVSFENPYHLFDVPRVRTLINTYGSSPVVLETLLAALQGKAPFAGSSPVDAFCGQWDTHL
What is the function of this protein?
Catalyzes the cleavage of beta-N-acetyl-D-glucosaminides and beta-D-glucosides.  Might be involved in the degradation of glucuronic acid-containing glycosaminoglycans such as hyaluronic acid.
What are the official names of this protein?
Beta-N-acetylglucosaminidase/beta-glucosidase, 3-beta-N-acetyl-D-glucosaminidase/beta-D-glucosidase, Nag3.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
Protein: FIXA_ECO27
Sequence: MKIITCYKCVPDEQDIAVNNADGSLDFSKADAKISQYDLNAIEAACQLKQQAAEAQVTALSVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQQTASVLAAAAQKAGFDLILCGDGSSDLYAQQVGLLVGEILNIPAVNGVSKIISLTADTLTVERELEDETETLSIPLPAVVAVSTDINSPQIPSMKAILGAAKKPVQVWSAADIGFNAEAAWSEQQVAAPKQRERQRIVIEGDGEEQIAAFAENLRKVI
What is the function of this protein?
Required for anaerobic carnitine reduction.  May bring reductant to CaiA.
What are the official names of this protein?
Protein FixA.
What is the protein family that this protein belongs to?
Belongs to the ETF beta-subunit/FixA family.
Protein: UFL1_ANOGA
Sequence: MADWDEIKRLAADFQKAQLSTGLQRLSERNCIEIVRLLIEKGLIDVIYTNDGKEYLTQDHLKQEVKDELYVRGGRVNLIELARVLNVDFGKIEYTAKRLVEKDPNLHLLLGQLIETSYLQRLASEINQKLVQYGEIHIGQLTTTYDLPTDFILNKIVLANLHKVIFAKQDPTNAHIFFTQSYIARNKAKIRGALAAITKPTPISVILNLTDVPARILYMSLNEMSSLGSVTVQSPAGQYIPHVYQRMQAQWVKDYFKQNGHIMYETVTKLGVSDVRSFVQAQLPDEKLVQLKNCIIGNRLIDQVKDSMDMCVTSNSYLDISTILPSSLSDDNIEEILTHILTPTIRKQTYVFGMVVLTVNFMDECVKGCLELVNEHAKRAVESGSYQKYIAEKSIKHQEVDHGVMEEEKADKREERRKKASTGKGGGGAQGRETKTKSTKKHARGTRGNVSDSDDGGEIQTNASNKKGGKDPHIELITAKEIAKVVEKTLEPEGLEMLAKDVANHYFPILSKQALVKAHELYEQSLQKNNQNRRQTHASIQEKLNTLYNDIRLYEKGLKLFPADVQGQLLKYLLKTFGTDACNELCLYVASECNLNTNFNAPLTTEQRTKIANDSGPEYRPHLQTLCKALSASETVEDFLDKTEKTMQACSMMLKKIDKKKDRNLILCHKHGLLEQLTNCTDPALVLHLAVLIIFTISTQTMLHASGRHVSAILTFLQTVLSTDDSKVFNNYHDLVLKLLSTESSTTEEAKANAEDITKQLGELTPVVKNIAGNFKKAGVTPVE
What is the function of this protein?
E3 UFM1-protein ligase that mediates ufmylation of target proteins.
What are the official names of this protein?
E3 UFM1-protein ligase 1 homolog, E3 UFM1-protein transferase 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the UFL1 family.
Protein: SOX10_RAT
Sequence: MAEEQDLSEVELSPVGSEEPRCLSPSSAPSLGPDGGGGGSGLRASPGPGELGKVKKEQQDGEADDDKFPVCIREAVSQVLSGYDWTLVPMPVRVNGASKSKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESDKRPFIEEAERLRMQHKKDHPDYKYQPRRRKNGKAAQGEAECPGGETDQGGAAAIQAHYKSAHLDHRHPEEGSPMSDGNPEHPSGQSHGPPTPPTTPKTELQSGKADPKRDGRSLGEGGKPHIDFGNVDIGEISHEVMSNMETFDVTELDQYLPPNGHPGHVGSYSAAGYGLSSALAVASGHSAWISKPPGVALPTVSPPAVDAKAQVKTETTGPQGPPHYTDQPSTSQIAYTSLSLPHYGSAFPSISRPQFDYSDHQPSGPYYGHAGQASGLYSAFSYMGPSQRPLYTAISDPSPSGPQSHSPTHWEQPVYTTLSRP
What is the function of this protein?
Transcription factor that plays a central role in developing and mature glia (By similarity).  Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination (By similarity).  Once induced, MYRF cooperates with SOX10 to implement the myelination program (By similarity).  Transcriptional activator of MITF, acting synergistically with PAX3 (By similarity).  Transcriptional activator of MBP, via binding to the gene promoter (PubMed:26525805).
What are the official names of this protein?
Transcription factor SOX-10.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CAV_DROSE
Sequence: MSGTQMSAFLRQYLADEDKKIRAQFKESDPNNKLILWMHEKTRITEEDLARPYTEDEVKELCLRTKVKVDMTAWNCLWEAKKRFEAKGRFVNKSERFINRMYVKAVRKKMVQPYPEEFVAQRREVVAAETKKHNISRLDRWQRKKTQNLSAQESSPARGAHLSFIDAMQTHEDQVNANLSSVSQINFQVEAIARPAVSSSDLSGIGDDEDEHQQSEFQDEHINCPETAINENSVRCDPINSGRMRTGCINSQGNNNTESDPDYYMFGTQLSSLLRPTSTQEPDDQVNCPETEMNESWVRCDQINSESMSIGPSIDSEGTITFQNSESEPIDVDSIA
What is the function of this protein?
Binds to chromosome ends in a sequence-dependent manner and is required for telomere capping.
What are the official names of this protein?
Telomere-binding protein cav, Protein caravaggio.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: KA162_MESMA
Sequence: MKIFSILLVALIICSISICTEAFGLIDVKCFASSECWTACKKVTGSGQGKCQNNQCRCY
What is the function of this protein?
Significantly inhibits voltage-dependent sodium current (Nav) and voltage-dependent delayed rectifier potassium current.
What are the official names of this protein?
Potassium channel toxin alpha-KTx 16.2, BmK 622, BmTx3B, Martentoxin.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 16 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MTLD_CHAGB
Sequence: MVQRNAPKKAVHFGAGNIGRGFVACFLHNSGYEVIFAEVNDTTVQKLNSQKSYKVIEVGADGTSESTITNYRAINSRLNEAELVQEIATADLVTCSVGPHILKFLAPVIAKGIDARSTDLTPVAVIACENAIGATDTLAEFIKAPENTNPDRLADYDKRARFANSAIDRIVPAQDPDAGLDVRLEKFYEWVVERTPFADHEPPAVEGIHWVDNLQPFIERKLYTVNTGHATAAYHGYIRRKSTVYDALQDREIQEEVKKALANTASLITQKHGIPQDEQQAYVDKIVRRISNPHLEDAVERVGRAPLRKLSRKERFIGPAAELAEHGKDCGALLDAAEMAFRFQNVEGDDESFKLAEIMEQNGPEDVVKQVCGLEPKEKLFPAVVDVVKRVQADTQSD
What is the function of this protein?
Catalyzes the NAD(H)-dependent interconversion of D-fructose 6-phosphate and D-mannitol 1-phosphate in the mannitol metabolic pathway.
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase, M1PDH, MPD, MPDH.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: RLMM_ECODH
Sequence: MNKVVLLCRPGFEKECAAEITDKAGQREIFGFARVKENAGYVIYECYQPDDGDKLIRELPFSSLIFARQWFVVGELLQHLPPEDRITPIVGMLQGVVEKGGELRVEVADTNESKELLKFCRKFTVPLRAALRDAGVLANYETPKRPVVHVFFIAPGCCYTGYSYSNNNSPFYMGIPRLKFPADAPSRSTLKLEEAFHVFIPADEWDERLANGMWAVDLGACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFKFRPTRSNISWMVCDMVEKPAKVAALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYIQAQLDEHGINAQIQARQLYHDREEVTVHVRRIWAAVGGRRDER
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_LACPL
Sequence: MSLQDRLTELRDQGLADIKSADVLKKVNQVKVDLLGKKGPITEVLRGMRDLSPEERPKVGAYANEVRDRIQAAIDERREELEQAAVNEQLAAEKLDVTLPGREVPQGQPHVITQIITELEDLFMGMGYQIVDGDEVEEDYYNFERLNLPKDHPARDMQDTFYITKDVLLRTQTSADQPRSLENHDFSKGPLKVLSPGRVYRRDTDDATHSHQFHQIEGLVVDKHITMADLKGTLILVAKTLFGDQFDVRLRPSFFPFTEPSVEADVTCFNCNGKGCAICKQTGWIEVLGAGMVHPHVLEMSGIDPEEYGGFAFGLGPDRFAMLKYGVDDIRNFYLNDVRFLSQFYKKG
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNC_BUCAT
Sequence: MNHIVTKKIQKVLGYTFTHKDLLKQALTHRSASSKHNERLEFLGDSILSFVIANALYQHFPYIDEGDMSRMRATLVRGNTLAEIAYEFDLGEYLKLGQGELKSGGFRRESILANTVEALIGSIYLDSNIKTVEELILKWYEKRLEKISPGDTQKDPKTRLQEYLQSKHLSLPLYFIVEVYGEAHNQLFTIHCKISTISEYLIGTGSSRRKAEQDAAQKALIKLGVE
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR5_ROSDO
Sequence: MNLPKNGMTYADAGVDIDAGNALVDRIKPAAKRTNRSGVMAGLGGFGALFDLKDAGYTDPILVAATDGVGTKLRIAIDTGHVDGVGIDLVAMCVNDLVCQGAEPLFFLDYFATGALETDKAARIIEGIALGCERAGCALIGGETAEMPGMYPAGDFDLAGFSVGAMERGAALPAHVAQGDVLLGLASDGVHSNGYSLVRKLVEVSGLSWDAPCPWAEQSLGAELLTPTRLYVKQALAAIDAGGVHALAHITGGGLTENLPRVLPEGLGADIDLSTWSLPAVFGWMAQTGGMQEAEMLKTFNCGIGMILVVAQEEADKLTQLLASLGEDVARIGHVSAREGVRYSGTLL
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.