PharMolix/UniProtQA huggingface dataset:
Protein: MYO7B_MOUSE
Sequence: MSVFRLGDHVWLDPPSSSKTGVAIGGIVKETKLGKTLIEDDEGKEHWVHAEDLSTLRPMHPNSAQGVDDMIRLGDLNEAGVVHNLLIRYQQHKIYTYTGSILVAVNPFQMLPLYTLEQVQIYYSRHMGELPPHIFAIANSCYFNMKKNKRDQCCIISGESGAGKTETTKLILQFLATVSGQHSWIEQQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIHFNSSGVIEGASIEHFLLEKSRVCRQAPEERNYHIFYCMLMGMSPEEKQMLSLGMPSEYHYLTMGSCTSSEGLSDAKDYAHVRSAMKILQFSDSENWDISKLLAAILHLGNVGFMAAVFENLDSSDVMETPAFPLAMKLLEVQHQALRDCLIKHTIPVLGEFVSRPVNIAQATDRRDAFVKGIYGRLFQWIVKKINAAIFTPQAQDPQNVRRAIGLLDIFGFENFQNNSFEQLCINFANEHLQQFFVKHVFTMEQEEYLSENITWNYIHYTDNQPILDMLALKPMSIISLLDEESRFPQGTDVTMLQKLNSIHANNKSFLSPRSIHDTRFGIAHFAGDVYYQAEGFLEKNRDVLSTDILILIHSSKNKFLKEIFNVDSSQTKLGHGTICQVKAGSQLFKSSDSIKRPVTLASQFKQSLDQLMRILTNCQPYFVRCIKPNEYKKPLLFDRELCIQQLRYSGMMETVHIRKSGFPIRYTFDEFSQRFRVLLPSPERMQFQNKPRQMTLHIADLCLGTDKDWKVGKTKIFLKDHQDTVLEIRRSQALDGAAIRIQRVLRGHKYRKEFLRQRRAAVTLQAGWRGYSQRKNFKLILVGFERLQAIARSHLLMRQFQAMRQRIVQLQARCRGYLVRQQVQAKRRAVVIIQAHARGMVVRKSYWQQKSTGPQVILAKEPKAQVAVHERKRKSIYDTVTDTAMVEKVFGFLPAMIGGQEGPAPTRFEDLEVKTQKLHEVDLDTVPMMAMPEEEVDSLAEYTFPKFAVTYFQKSASHTHIQKPLRYPLLYHENDTDHSAALDVWIIILRFMGDLPEPVVYGRNSLTGSSVMRQIHDKLGKDSVTQHNRSSQVASQLNFGEEAFKFDGPISDRPMSNLEKVHFIVGYAIMRPGLRDEIYCQICKQLSENYKTSSRARGWILLSLCLGCFPPSERFMKYLLNFISQGPPSYGPFCAERLQRTFANGVRAEPPTWLELQAVKSKKHIPIQVILATGRSLTISVDSASTSREICQHVAQKQGLRDNLGFSLQVAVYDKFWSLGSGCDHLMDAVAQCEQLARERGESQRQAPWRIYFRKEFFTPWHDSQEDPVSTELIYHQVLRGVWSGEYNFEKEEELVELLARHCYVQLGATVKSNAVQELLPSCVPSKLYRTKSPEKWASLVTAAHAKAQYTQSKATPLAVREQTVEAARLLWPLLFSRLFEVTTLSGPRLPKTQLVLAINWKGMYFLDQKERTLLGLSFAEVMGLVANRDAPGGKKLLLATLQEEYEFVSPSSVAIAEMVALFLGGLKERSVFAMALQDRRATDDITLLPFKKGDLLILTKKQGLLASENWALGQNDRTGKTGLVPTACLYTIPSVTKPSTQLLSLLAMSPEKRKLAAQEVRALEPPLEDQLTESPYTLEEFSYQFFRAPEKETISRAAMPMARSRGHLWAYSPEPLRQPLLKSVHDKAKLRDAACQIFLAILKYTGDYPSRQSWHSLELTDQMFSLALQDPALQDELYCQILKQLTHNSIRFSEERAWQLLWLCTGLFPPGKTLLPHAQKFIDSRKKKPLALDCSRRLHRVLRVGPRKQPPHDVEVKAAEQNVSKLHHEVYLPNDTSKSMEVGSSSRVRDLCEGIGTRLQLASWDGCSLFIKITDKVISLKEGDFFFDSLRQVSDWVKKNRPQKEGASVTLPYQVFFMRKLWLNVTPGKDVNADTILHYHQELPKYLRGFHKCSREDAIHLGGLICKIQFGSDSSQLASVSKVLKELVPQNLTRLMSSEEWKKSLLLECDKNKRKTVAEAKVEFLKYMYRWPTFGSAFFEVKQTSEPSYPDILLIAINRHGLLLIHPKTKELLNTYPFTKISSWSSGNTYFHMALGSLGQGSRLLCETSLGYKMDDLLTSYVQQLLNTVNKQRGFRAPAPANP
What is the function of this protein?
Myosins are actin-based motor molecules with ATPase activity.  Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments.  As part of the intermicrovillar adhesion complex/IMAC plays a role in epithelial brush border differentiation, controlling microvilli organization and length.  May link the complex to the actin core bundle of microvilli.
What are the official names of this protein?
Unconventional myosin-VIIb.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, microvillus. Note=Enriched in the microvilli of the intestinal brush border.
Protein: RS6_FRATT
Sequence: MKHYEVVLMIHPDQSDQLDAMLGKYRGIIEEKGGKIHRFEDWGRRQLAYPIEKLHKAHYVLFNIECPTESLEKLQESLRYNDAILRRLVIATKEAITEPSVMMESNEKEVI
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: YAIW_ECOLI
Sequence: MSRVNPLSSLSLLAVLVLAGCSSQAPQPLKKGEKAIDVASVVRQKMPASVKDRDAWAKDLATTFESQGLAPTLENVCSVLAVAQQESNYQADPAVPGLSKIAWQEIDRRAERMHIPAFLVHTALKIKSPNGKSYSERLDSVRTEKQLSAIFDDLINMVPMGQTLFGSLNPVRTGGPMQVSIAFAEQHTKGYPWKMDGTVRQEVFSRRGGLWFGTYHLLNYPASYSAPIYRFADFNAGWYASRNAAFQNAVSKASGVKLALDGDLIRYDSKEPGKTELATRKLAAKLGMSDSEIRRQLEKGDSFSFEETALYKKVYQLAETKTGKSLPREMLPGIQLESPKITRNLTTAWFAKRVDERRARCMKQ
What are the official names of this protein?
Uncharacterized protein YaiW.
Protein: SARR_STAAW
Sequence: MSKINDINDLVNATFQVKKFFRDTKKKFNLNYEEIYILNHILRSESNEISSKEIAKCSEFKPYYLTKALQKLKDLKLLSKKRSLQDERTVIVYVTDTQKANIQKLISELEEYIKN
What is the function of this protein?
Negative regulator of sarA transcription at late exponential and stationary growth phases.  It contributes to the modulation of target genes downstream of the sarA regulatory cascade.  Also, positively regulates expression of primary transcripts RNAII and RNAIII generated by agr (virulence accessory gene regulator) locus (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator SarR, Staphylococcal accessory regulator R.
What is the protein family that this protein belongs to?
Belongs to the SarA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_CUPNH
Sequence: MQTALLKPKIIAVEPLGDHHAKVVMEPFERGYGHTLGNALRRVLLSSMVGYAPTEVTIAGVVHEYSTIDGVQEDVVNLLLNLKGVVFKLHNRDEVTVSLRKDGEGVVTAADIELPHDVEIINPNHVIAHLSAGGKLDMQIKVEQGRGYVPGNVRKFGDESGKVIGRIVLDASFSPVRRVSYAVESARVEQRTDLDKLVMNIETDGVISPEEAIRQSARILVDQLSVFAALEGTESAAEAASSRTPQIDPILLRPVDDLELTVRSANCLKAENIYYIGDLIQRTENELLKTPNLGRKSLNEIKEVLASRGLTLGMKLENWPPAGLEK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: EX7S_SHIB3
Sequence: MPKKNEAPASFEKALSELEQIVTRLESGDLPLEEALNEFERGVQLARQGQAKLQQAEQRVQILLSDNEDASLTPFTPDNE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUT_NITOC
Sequence: MPKVQLKILDSRLGKEFPLPDYATAGAAGLDLRACIERPLAILPGATKLIPTGLAIYIADPRFAAVLLPRSGLGHKQGIVLGNLVGLIDSDYQGEILVSCWNRGAEPFTLAVGERIAQMIFVPVVQMEFEQVETFTATLRGEGGFGHTGRH
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: KTHY_TROWT
Sequence: MFVTFEGIDGSGKTAQLTAAGEFLKASGKQVVLTREPGTISCIRDYVLASDMDIRTEALLYSADRAENIAKNVIPALNAGKVVLQDRYLDSFLAYQLADNKLVETDIMRLFEFSSQGLRPDLTLLFDLTPACAQERLENRDRIERKPIDFHSKVRNIYLKLSADNTDRIRVIDASQSFSKIHQQVIYHIERKLGGTHSA
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: CTTB2_HUMAN
Sequence: MATDGASCEPDLSRAPEDAAGAAAEAAKKEFDVDTLSKSELRMLLSVMEGELEARDLVIEALRARRKEVFIQERYGRFNLNDPFLALQRDYEAGAGDKEKKPVCTNPLSILEAVMAHCKKMQERMSAQLAAAESRQKKLEMEKLQLQALEQEHKKLAARLEEERGKNKQVVLMLVKECKQLSGKVIEEAQKLEDVMAKLEEEKKKTNELEEELSAEKRRSTEMEAQMEKQLSEFDTEREQLRAKLNREEAHTTDLKEEIDKMRKMIEQLKRGSDSKPSLSLPRKTKDRRLVSISVGTEGTVTRSVACQTDLVTENADHMKKLPLTMPVKPSTGSPLVSANAKGSVCTSATMARPGIDRQASYGDLIGASVPAFPPPSANKIEENGPSTGSTPDPTSSTPPLPSNAAPPTAQTPGIAPQNSQAPPMHSLHSPCANTSLHPGLNPRIQAARFRFQGNANDPDQNGNTTQSPPSRDVSPTSRDNLVAKQLARNTVTQALSRFTSPQAGAPSRPGVPPTGDVGTHPPVGRTSLKTHGVARVDRGNPPPIPPKKPGLSQTPSPPHPQLKVIIDSSRASNTGAKVDNKTVASTPSSLPQGNRVINEENLPKSSSPQLPPKPSIDLTVAPAGCAVSALATSQVGAWPAATPGLNQPACSDSSLVIPTTIAFCSSINPVSASSCRPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRPTLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAADKNGFTPLCAAAAQGHFECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHAAVDTGNVDSLKLLMYHRIPAHGNSFNEEESESSVFDLDGGEESPEGISKPVVPADLINHANREGWTAAHIAASKGFKNCLEILCRHGGLEPERRDKCNRTVHDVATDDCKHLLENLNALKIPLRISVGEIEPSNYGSDDLECENTICALNIRKQTSWDDFSKAVSQALTNHFQAISSDGWWSLEDVTCNNTTDSNIGLSARSIRSITLGNVPWSVGQSFAQSPWDFMRKNKAEHITVLLSGPQEGCLSSVTYASMIPLQMMQNYLRLVEQYHNVIFHGPEGSLQDYIVHQLALCLKHRQMAAGFSCEIVRAEVDAGFSKEQLLDLFISSACLIPVKQSPSKKKIIIILENLEKSSLSELLRDFLAPLENRSTESPCTFQKGNGLSECYYFHENCFLMGTIAKACLQGSDLLVQQHFRWVQLRWDGEPMQGLLQRFLRRKVVNKFKGQAPSPCDPVCKIVDWALSVWRQLNSCLARLGTPEALLGPKYFLSCPVVPGHAQVTVKWMSKLWNGVIAPRVQEAILSRASVKRQPGFGQTTAKRHPSQGQQAVVKAALSILLNKAVLHGCPLPRAELDQHTADFKGGSFPLSIVSSYNTCNKKKGESGAWRKVNTSPRRKSGRFSLPTWNKPDLSTEGMKNKTISQLNCNRNASLSKQKSLENDLSLTLNLDQRLSLGSDDEADLVKELQSMCSSKSESDISKIADSRDDLRMFDSSGNNPVLSATINNLRMPVSQKEVSPLSSHQTTECSNSKSKTELGVSRVKSFLPVPRSKVTQCSQNTKRSSSSSNTRQIEINNNSKEVNWNLHKNEHLEKPNK
What is the function of this protein?
Regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurons, thus controls dendritic spinogenesis and dendritic spine maintenance.
What are the official names of this protein?
Cortactin-binding protein 2, CortBP2.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Cell projection, dendritic spine. Note=Remains associated with dendritic spines even after glutamate stimulation.
Protein: AVRA_STRVR
Sequence: MSAYRHAVERIDSSDLACGVVLHSAPGYPAFPVRLATEIFQRALARLPGDGPVTLWDPCCGSGYLLTVLGLLHRRSLRQVIASDVDPAPLELAAKNLALLSPAGLTARELERREQSERFGKPSYLEAAQAARRLRERLTAEGGALPCAIRTADVFDPRALSAVLAGSAPDVVLTDLPYGERTHWEGQVPAQPVAGLLRSLASALPAHAVIAVTDRSRKIPVAPVKALERLKIGTRSAVLVRAADVLEAGP
What is the function of this protein?
Specifically methylates the guanine-2535 in 23S ribosomal RNA.  Confers resistance to antibiotic avilamycin, an orthosomycin antibiotic.
What are the official names of this protein?
23S rRNA (guanine(2535)-N(1))-methyltransferase, Avilamycin resistance protein A.
Protein: LEAD7_GOSHI
Sequence: MASHEQSYKAGRAEGRAHEKGEQMKESMKEKAEAAKQKTMETAEAAKQKTMETAEAAKQKTRGAAETTNDKTKQTAGAARGKAEETKETSGGILQQAGEKVRNAAQGATDAVKHTFGMADADEDEHNYPATVTRKD
What is the function of this protein?
LEA proteins are late embryonic proteins abundant in higher plant seed embryos.  There are two subsets of LEA proteins (5a and 5b), the first ones are expressed when the cotyledon weight reach 80 mg and the second set are expressed above 100 mg.  The function of those proteins is not known.
What are the official names of this protein?
Late embryogenesis abundant protein D-7, LEA D-7.
What is the protein family that this protein belongs to?
Belongs to the LEA type 4 family.
Protein: THNE_TRIHA
Sequence: MSSATTMGQLPQHQTAIVAQGPGQMTIQKDAPVPALAHDMVLVKTATVAINPVDVKSLDYSPAPGAIIGFDFAGTIVALGSDAVKEGRLAVGDRVAGVVYGMDRLQPDVGAFAQYVGALADLVLKLPDHISLEDAAALGLATATAAYGLFKEMELPGALDRLSSSVPDRGDFVLVAGGSTATGTRAIELLKTAGFRPVATSSPSNFELVKKFGAEAVFDYHDPGCADAIKAYTNNELDYALDCIAEAETTQLCYAAIGRAGGRYVAVEPFRESIAQSRINTVKASWFNVMTVWGRKVELGGEYAREASLEDREFGARSFAAVQALLDRGYVTTHPIKLMSGGWEGVVEGVAKIRSQPPSGYKLVCQVA
What is the function of this protein?
Trans-enoyl reductase; part of the gene cluster that produces the tetronate natural products trihazones (PubMed:33570538).  The PKS-NRPS synthetase thnA with the help of the trans-enoyl reductase thnE are responsible for the synthesis of the carboxylmethyl containing trihazone A (PubMed:33570538).  The PKS portion of thnA synthesizes beta-keto-triene chain from one acetyl-CoA and 6 equivalents of malonyl-CoA, in collaboration with thnE, which selectively reduces the enoyl intermediate during the first and fourth iteration of the PKS (PubMed:33570538).  The NRPS domain selects and activates malate, of which the alpha-hydroxyl group attacks the completed polyketide acyl-S-ACP chain to form the ester product (PubMed:33570538).  Intramolecular Dieckmann cyclization catalyzed by the terminal reductase domain releases the product as trihazone A from the PKS-NPRS (PubMed:33570538).  The pathway begins with the formation of trihazone A by the hybrid PKS-NRPS synthetase thnA and the trans-enoyl reductase thnE.  Trihazone A is further decarboxylated by the 2-oxoglutarate-dependent dioxygenase thnC to produce trihazone D.  The function of the FAD-dependent monooxygenase thnD has still to be identified (PubMed:33570538).
What are the official names of this protein?
Trans-enoyl reductase thnE, Trihazone biosynthesis cluster protein E.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: NOP2_SCHPO
Sequence: MGRKQKSKQGIPPTLEENHNSSHKVTENAKKRKHSKEKPQNSRKRQLAEEKKSLFENSDSENEKDLIDADEFEEAETLSDLEHDEEPQTFADEFIDDEAKECEGEEEDSVFDSDEEHEVKPMFSDDSGDEEDLELANMEAMSRKLDEEAELEEKEAEEELHTNIHPEAPTVLPPIDGFTDSQPISTLPQDLSQIQLRIQEIVRVLNDFKNLCEPGRNRSEYVDQLLNDICAYYGYSRFLAEKLFELFSVSEAVEFFEANEMPRPVTIRTNTLKTQRRELAQALINRGVNLEPIGKWSKVGLQVFESQVPIGATPEYLAGHYILQAASSFLPVMALAPQPNERILDMSSAPGGKVTYVAALQKNTGIIFANDSNKARTKALSANIHRLGVRNAIVCNYDGRKFPNEVIGGFDRVLLDAPCSGTGVIYKDQSVKTNKSERDFDTLSHLQRQLLLSAIDSVNADSKTGGFIVYSTCSITVDEDEAVIQYALKKRPNVKLVSTGLEFGREGFTRFREKRFHPSLKLTRRYYPHVHNIDGFFVAKLKKISDKIPTVNVADDMKDGTNNDVEIEKNSTEIDNITFNDEADKEIIEQNRRKWLKSKGYKVAKKKD
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C(5) position of a cytosine in 25S rRNA.  Required for 60S ribosomal subunit synthesis and processing (By similarity).
What are the official names of this protein?
25S rRNA (cytosine-C(5))-methyltransferase nop2, Nucleolar protein 2.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus.
Protein: TAF10_DROME
Sequence: MASDGEDISVTPAESVTSATDTEEEDIDSPLMQSELHSDEEQPDVEEVPLTTEESEMDELIKQLEDYSPTIPDALTMHILKTAGFCTVDPKIVRLVSVSAQKFISDIANDALQHCKTRTTNIQHSSGHSSSKDKKNPKDRKYTLAMEDLVPALADHGITMRKPQYFV
What is the function of this protein?
TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors.
What are the official names of this protein?
Transcription initiation factor TFIID subunit 10, Transcription initiation factor TFIID 24 kDa subunit, TAFII-24, TAFII24, dTAF(II)24.
What is the protein family that this protein belongs to?
Belongs to the TAF10 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RECX_NEIG2
Sequence: MKPQKSLRARAMDILSRQEVSRIGLKRKLAPHAESEEELENVLNEFAERNWQSDLRYAEAYIRSKSRKHGSLRLKQALAQQGIDEKTSRNLLPDRSSEKQAAIAVLRKKFKHPAANLKEKQKQARFLAYRGFDADTVQTALKHAWDENWEDSC
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SIP5_YARLI
Sequence: MGNVPGKEQQVRNARSVSEDYHREGQVRSKRPSAPREKKREPRVFVDPNEQVDGGYLVPQGVYTGPQDFDILVVKSLMTSRKLAPFFKGLQDYEEEWTDHQLMAAIRGFPIPSAASESPTTESTDTKDASASTSTPHAISTPSHLSPPTAPPQVAISPPRHTLSSNNPFRDPLEHMSHLRIDLDNTTFSQSAPTPSWMRSGEPDQEDGDELINPGILQSPPSREAPKPPPSRQRAKTLTNKEPPLMVKIYRDPIECPICFLYYPNSLNMTRCCAQPICSECFVQMKRAEPHPRHDEPEPDTLLGQLDLISEPTACPYCAMSDFGVVYSPRHGPGAKAAGANSADAAAAKGNGDESAIDDSGDSSDGIDTTNMDDVADKLMHMSGAKRRSSISVTNPNVVTVDRVRPDWSKTLAAARARAARKAATANALHATAFVEGGNGEVAGSSRSSRRTRQNHEQRQAARAQELEQIMLSEAMRLSMLESQEAEEKRSREQESK
What is the function of this protein?
May negatively regulate the SNF1 kinase.
What are the official names of this protein?
Protein SIP5.
What is the protein family that this protein belongs to?
Belongs to the SIP5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEPR2_ARATH
Sequence: MRNLGLLEITLLCSLFVYFRIDSVSSLNSDGLALLSLLKHFDKVPLEVASTWKENTSETTPCNNNWFGVICDLSGNVVETLNLSASGLSGQLGSEIGELKSLVTLDLSLNSFSGLLPSTLGNCTSLEYLDLSNNDFSGEVPDIFGSLQNLTFLYLDRNNLSGLIPASVGGLIELVDLRMSYNNLSGTIPELLGNCSKLEYLALNNNKLNGSLPASLYLLENLGELFVSNNSLGGRLHFGSSNCKKLVSLDLSFNDFQGGVPPEIGNCSSLHSLVMVKCNLTGTIPSSMGMLRKVSVIDLSDNRLSGNIPQELGNCSSLETLKLNDNQLQGEIPPALSKLKKLQSLELFFNKLSGEIPIGIWKIQSLTQMLVYNNTLTGELPVEVTQLKHLKKLTLFNNGFYGDIPMSLGLNRSLEEVDLLGNRFTGEIPPHLCHGQKLRLFILGSNQLHGKIPASIRQCKTLERVRLEDNKLSGVLPEFPESLSLSYVNLGSNSFEGSIPRSLGSCKNLLTIDLSQNKLTGLIPPELGNLQSLGLLNLSHNYLEGPLPSQLSGCARLLYFDVGSNSLNGSIPSSFRSWKSLSTLVLSDNNFLGAIPQFLAELDRLSDLRIARNAFGGKIPSSVGLLKSLRYGLDLSANVFTGEIPTTLGALINLERLNISNNKLTGPLSVLQSLKSLNQVDVSYNQFTGPIPVNLLSNSSKFSGNPDLCIQASYSVSAIIRKEFKSCKGQVKLSTWKIALIAAGSSLSVLALLFALFLVLCRCKRGTKTEDANILAEEGLSLLLNKVLAATDNLDDKYIIGRGAHGVVYRASLGSGEEYAVKKLIFAEHIRANQNMKREIETIGLVRHRNLIRLERFWMRKEDGLMLYQYMPNGSLHDVLHRGNQGEAVLDWSARFNIALGISHGLAYLHHDCHPPIIHRDIKPENILMDSDMEPHIGDFGLARILDDSTVSTATVTGTTGYIAPENAYKTVRSKESDVYSYGVVLLELVTGKRALDRSFPEDINIVSWVRSVLSSYEDEDDTAGPIVDPKLVDELLDTKLREQAIQVTDLALRCTDKRPENRPSMRDVVKDLTDLESFVRSTSGSVH
What is the function of this protein?
Acts as a receptor for PEP defense peptides.  Unlike typical immune receptors, senses an endogenous elicitor that potentiates PAMP-inducible plant responses (By similarity).
What are the official names of this protein?
Leucine-rich repeat receptor-like protein kinase PEPR2, Elicitor peptide 1 receptor 2, PEP1 receptor 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: KDSB_HELPH
Sequence: MIIIPARLKSSRFENKVLEDIFGLPMVVRCAKNANLVDECVVACDDESIMQTCQKFHIKAVLTSKHHNSGTERCLEAARILGLKNDERVLNLQGDEPFLEKEVILALLEATKNAPFMATCAKVIDEEQAKSPNLVKVVLDSQNNALYFSRSLIPFLRDFDAKRQTPLLGHIGIYGFHNKEILEELCTLKPCVLEDTEKLEQLRALYYQKKIAVKIVQSQSVGIDTQEDLENALKIFSPNLLER
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4HM_SINFN
Sequence: MVFTGKCDLRSPLLGRRLRLGFIGGGKGGLVGRWHFAGARLSNHWEIVAGALSSDPENAHASAAEWMIAPDRSYSDWNAMATAEAARDDGIEAVSIVTPNWTHHRIATAFLKAGIDVILDKPMTTTVSDARELVELQRATDRLVIMTYPYAHHAMVRQAKHMIRNGAVGTVRQAHVEYVQEWATAPFSSDAKGAMWRQDPEKVGRASATGDIGTHAYHLLHTLTGQDIARLRAEFHTCGAVKAMEDTAYVTFRLENGAPGILWVTQAAPGQYCGLRIRVWGDRGGLEWDQEKPEALRYVPLGEQEQIFVRGHGSGIVPEAERLIHLPRGHGEALVDAWANLYAEAGVAVAARRAGYALPKDSVELSGVEDGLKGMLFIDACADSHESGGSWVSINGESIPNFC
What are the official names of this protein?
Uncharacterized oxidoreductase y4hM.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
Protein: SYY_BORPA
Sequence: MSHPEAPITPEVEADLAIARRGCDELLVESEFARKLARSRATGVPLRIKLGLDPTAPDIHLGHTVVLNKMRQLQDLGHNVIFLIGDFTSTIGDPSGRNSTRPPLTREQIETNAKTYYAQASLVLDPARTEIRYNSEWCDPLGARGMIQLASRYTVARMMEREDFTRRFKGGVPIAVHEFLYPLLQGYDSVALKADLELGGTDQKFNLLVGRELQKEYGQEQQCILTMPLLVGTDGVEKMSKSKGNYIGISEAPESMFGKLMSISDMLMWRYYELLSFRSLADIAALKAEIDGGRNPRDAKVALAQEIVARFHSPQAAEAALAAFEARFRDGAIPEDMPEVTVGGAPQGILRILREAGLVASGSEAQRNVEQGGVRVNGDRVEDKSLQLSAGTYVVQVGKRKFARVKLVG
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMT14_ALTAL
Sequence: MPASDPRRLRSPLNPSIHSPFVIRQLPFEMDFSATASLPIGFSSLFLLTEVYIRHVESSRRRDISLLSNCWYIAVNTGLWICCLVLSIVALVLRIEAVSLSSCQLAWMQAAVLKASDAQLWQPSADQLQVYHLRILLFLPGESSWPYGVLALVLTACLQCAAAGLCVWDAAPGLTPHLTRSALVPILHVGWGLHYTVFLLWILRICSLKGNDLRHIWKWRVWCLLVAPLFISALVGATPLTLWYPPKITFLFWCRKQQMRWRMLGERGAVQSLRSVSSTVRAQPTSHPYPAAL
What is the function of this protein?
Part of the gene clusters that mediate the biosynthesis of AM-toxins, host-selective toxins (HSTs) causing Alternaria blotch on apple, a worldwide distributed disease (Probable).  AM-toxins are cyclic depsipeptides containing the 3 residues 2-hydroxy-isovaleric acid (2-HIV), dehydroalanine, L-alanine which are common for all 3 AM-toxins I to III.  The fourth precursor is L-alpha-amino-methoxyphenyl-valeric acid (L-Amv) for AM-toxin I, L-alpha-amino-phenyl-valeric acid (L-Apv) for AM-toxin II, and L-alpha-amino-hydroxyphenyl-valeric acid (L-Ahv) for AM-toxin III (Probable).  AM-toxins have two target sites for affecting susceptible apple cells; they cause invagination of the plasma membrane and electrolyte loss and chloroplast disorganization (PubMed:22846083).  The non-ribosomal peptide synthetase AMT1 contains 4 catalytic modules and is responsible for activation of each residue in AM-toxin (PubMed:10875335).  The aldo-keto reductase AMT2 catalyzes the conversion of 2-keto-isovaleric acid (2-KIV) to 2-hydroxy-isovaleric acid (2-HIV), one of the precursor residues incorporated by AMT1 during AM-toxin biosynthesis, by reduction of its ketone to an alcohol (PubMed:15066029).  The cytochrome P450 monooxygenase AMT3 and the thioesterase AMT4 are also important for AM-toxin production, but their exact function within the AM-toxin biosynthesis are not known yet (PubMed:17990954).  Up to 21 proteins (including AMT1 to AMT4) are predicted to be involved in AM-toxin biosynthesis since their expression ishighly up-regulated in AM-toxin-producing cultures (PubMed:17990954).
What are the official names of this protein?
AM-toxin biosynthesis protein 14.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y4SN_SINFN
Sequence: MDCDGLRDDQWERIRGFVPGGTKGKRGPRTNNRLFLDALLWMARSGGRWRDLPERLGDYRAVKRRYYRWIEMGVLDEMLAVLAREADLEWLMIDSTIVRAHQHAAGARRAKGGRMPRAWVGLEAG
What are the official names of this protein?
Uncharacterized protein y4sN.
What is the protein family that this protein belongs to?
To transposase of insertion sequence IS6501.
Protein: DXS_MYCSJ
Sequence: MLEQIRGPADLQHLSQSALSELAGEIRQFLIHKVAATGGHLGPNLGVVELTLALHRVFDSPHDPLIFDTGHQAYVHKMLTGRSHEFDSLRKKDGLSGYPSRSESEHDWVESSHASAALSYADGLAKAFELTGHRNRHVVAVVGDGALTGGMCWEALNNIAAARRPVVIVVNDNGRSYAPTIGGFADHLAALRLQPGYERVLEEGRKAVRGLPVIGEFCYQCMHSVKAGIKDALSPQVMFTDLGLKYVGPIDGHDEHAVESALRHARGFNAPVIVHVVTRKGMGYAPAENDEAEQMHACGVIDVATGRATMVAAPGWTSSFSEALIDYGAKRRDIVAITAAMPGPTGLSAFRDRFPDRFFDVGIAEQHAMTSAAGLAMGGLHPVVAIYSTFLNRAFDQLMMDVALHKLPVTLVLDRSGVTGPDGASHNGMWDLSVLGIVPGMRVAAPRDGARLREELGEALDVNDAPTAIRFPKGDVGEDIPAVRRHRGVDVLAEPADGLSDDVLLVAVGPFASMALTVAERLRKQGIGVTVVDPRWVLPVPEVLTEFAAAHKLVVTVEDNGLHGGIGSSVSAALRHAEVDVPCRDVGLPQQFFDHASRGEVLADVGVTDRNISRQITGWVAALGATPADADEVSERLD
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.