PharMolix/UniProtQA huggingface dataset:
Protein: HLDD_VIBC3
Sequence: MIIVTGGAGMIGSNIIKALNERGITDILVVDHLKNGRKFKNLVDLQIADYMDRDDFLAQIMAGDDFGFIDAIFHEGACSATTEWDGKYVMLNNYEYSKELLHYCLDREIPFLYASSAATYGETDTFIEEPQYEGALNVYGYSKQQFDNYVRRLWLDAKQHDETLSQITGFRYFNVYGPREQHKGSMASVAFHLNNQMNAGENPKLFAGSENFKRDFVYVGDVAAVNLWFLDHGVSGIFNCGTGKAESFNEVAKAVIAFHGRGEVETIPFPDHLKGAYQEFTEADLTKLRAAGCDVQFKSVAEGVAEYMALINRK
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: RL33_VIBCH
Sequence: MAKGIREKIRLVSSAGTGHFYTTDKNKRNMPGKFEIKKYDPVVRQHVVYKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RPB10_ASFB7
Sequence: MLIPVVCFTCGFPIGTYAAIFDKARTEYIKTKMDGTLPQNIPLDASLQIELKDLITALGIPMRVCCRTHLITTLDYRKYY
What is the function of this protein?
Component of the DNA-directed RNA polymerase (RNAP) that catalyzes the transcription in the cytoplasm of viral DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase RPB10 homolog, RPB10 homolog.
What is the protein family that this protein belongs to?
Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: YNF8_YEASO
Sequence: MXKKNFIPSVSLVRRDLPTLVTTTTSSTALSKPTSSVVSETSSKSLPSLTSSAFSTSSGXTSSSSLIVASITPPSTVGNPFILNAADKPNGTVYIAVGAVIGAIFISILIWWLVSXYLSRRFTMTNSYANDSKNLYRGHHKHSSSLQSNPFDINDEKSYMQDDWDSMSQLESSQYEDAASPFNPIQDPFTDNRRSLFISPTLQVSQYEKSHSRHQSKDTNIFIDDPSLYVGTYLEEEEEEERKLNLNRPQRAASPERKEKKINSMEGYHKRNQSSLGLIPVASATSNTSSPKKAHKRQAPSMFLDDVLNGREII
What are the official names of this protein?
Vacuolar membrane protein FOSTERSO_4058.
What is the protein family that this protein belongs to?
Belongs to the PRM5 family.
What are the subcellular locations of this protein?
Vacuole membrane; Single-pass membrane protein.
Protein: ADCS_STRVP
Sequence: MRTLLIDNYDSFTHNLFQYIGEATGQPPVVVPNDADWSRLPLEDFDAIVVSPGPGSPDRERDFGISRRAITDSGLPVLGVCLGHQGIAQLFGGTVGLAPEPMHGRVSEVRHTGEDVFRGLPSPFTAVRYHSLAATDLPDELEPLAWSDDGVVMGLRHREKPLWGVQFHPESIGSDFGREIMANFRDLALAHHRARRDAADSPYELHVRRVDVLPDAEEVRRGCLPGEGATFWLDSSSVLEGASRFSFLGDDRGPLAEYLTYRVADGVVSVRGSDGTTTRTRRPFFSYLEEQLERRRVPVAPDLPFEFNLGYVGYLGYELKAETTGDPAHRSPHPDAAFLFADRAIALDHQEGCCYLLALDRRGHDDGARAWLRETAETLTGLAVRVPAEPTPAMVFGVPEAAAGFGPLARARHDKDAYLKRIDECLKEIRNGESYEICLTNMVTAPTEATALPLYSALRAISPVPYGALLEFPELSVLSASPERFLTIGADGGVESKPIKGTRPRGGTAEEDERLRADLAGREKDRAENLMIVDLVRNDLNSVCAIGSVHVPRLFEVETYAPVHQLVSTIRGRLRPGTSTAACVRAAFPGGSMTGAPKKRTMEIIDRLEEGPRGVYSGALGWFALSGAADLSIVIRTIVLADGRAEFGVGGAIVSLSDQEEEFTETVVKARAMVTALDGSAVAGAR
What is the function of this protein?
Involved in chloramphenicol biosynthesis (PubMed:8704974).  Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine (By similarity).
What are the official names of this protein?
Aminodeoxychorismate synthase, ADC synthase, 4-amino-4-deoxychorismate synthase, p-aminobenzoate synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the anthranilate synthase component I family.
Protein: GABD1_MYCBP
Sequence: MPIATINPATGETVKTFTAATDDEVDAAIARAHRRFADYRQTSFAQRARWANATADLLEAEADQAAAMMTLEMGKTLAAAKAEALKCAKGFRYYAENAEALLADEPADAAKVGASAAYGRYQPLGVILAVMPWNFPLWQAVRFAAPALMAGNVGLLKHASNVPQCALYLADVIARGGFPDGCFQTLLVSSGAVEAILRDPRVAAATLTGSEPAGQSVGAIAGNEIKPTVLELGGSDPFIVMPSADLDAAVSTAVTGRVQNNGQSCIAAKRFIVHADIYDDFVDKFVARMAALRVGDPTDPDTDVGPLATEQGRNEVAKQVEDAAAAGAVIRCGGKRLDRPGWFYPPTVITDISKDMALYTEEVFGPVASVFRAANIDEAVEIANATTFGLGSNAWTRDETEQRRFIDDIVAGQVFINGMTVSYPELPFGGVKRSGYGRELSAHGIREFCNIKTVWIA
What is the function of this protein?
Catalyzes the NADP(+)-dependent oxidation of succinate semialdehyde to succinate.  It is believed to be the main source of succinate semialdehyde dehydrogenase activity in Mycobacterium (By similarity).
What are the official names of this protein?
Succinate-semialdehyde dehydrogenase [NADP(+)] 1, SSADH 1, SSDH 1.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: OS9_EMENI
Sequence: MRRQSRIVASLLVLACASSGAFAHRKFNVHDDLLAYPQFRIKFPDGFILESQARAFLEQAPYSSPDLNDISEQTPLKDESEESIRDGSSGEKAKFSYEELSLEGQRYLCQIPVVEDGDSNRTKVEVNEEEERKELARATDRGLELLREMEGKCLYYISGWWSYSFCYMNQIKQFHALPSGGGVPNYPPMEDHTTHSFILGRFPQEEGQDEGKGAKSGKSSTELAELQTKGGSRYLVQRLESGDQCDLTGKNRKIEVQFHCNPQSTDRIAWIKELYTCSYLMLIYTPRLCNDVAFLPPQQEEVHTIECREILTPEEVTGWQAMHEYQLSQQLVESAEAPKHQVIGGIEVGAQRLVGTEGKRIEKGRVASIGEEKVDVVAKRVNGEVQLLSAEELKKFDLDEAKIEELRKKLEEWAKGKDWTLEIVTGNGAYLRGVVDTDEDEEDGYENEEGETDKREQRENTQETTGQPGQPGHQEETESGQAGHPMDDRSEDGEDPDVDGSEEIFKDEL
What is the function of this protein?
Lectin involved in the quality control of the secretory pathway.  As a member of the endoplasmic reticulum-associated degradation lumenal (ERAD-L) surveillance system, targets misfolded endoplasmic reticulum lumenal glycoproteins for degradation (By similarity).
What are the official names of this protein?
Protein OS-9 homolog.
What is the protein family that this protein belongs to?
Belongs to the OS-9 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side.
Protein: HFQ_ECODH
Sequence: MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVSHHSNNAGGGTSSNYHHGSSAQNTSAQQDSEETE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: RISB_STRA3
Sequence: MTIIEGQLVANEMKIGIVVSRFNELITSKLLSGAVDGLLRHGVSEEDIDIVWVPGAFEIPYMARKMALYKDYDAIICLGVVIKGSTDHYDYVCNEVTKGIGHLNSQSDIPHIFGVLTTDNIEQAIERAGTKAGNKGYDCALSAIEMVNLDKKLRER
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: Y1438_BDEBA
Sequence: MLRAAIAFFIIAIVAYIFGASGVAGMSVEIGRILLFVFLALAIISFVINLVSGRKP
What are the official names of this protein?
UPF0391 membrane protein Bd1438.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y5621_BURL3
Sequence: MAGHSKWANIKHKKAAADAKRGKIWTRLIKEIQVAARLGGGDVNSNPRLRLAVDKAADANMPKDNVKRAIDRGVGGADGANYEEIRYEGYGISGAAIIVDTLTDNRTRTVAEVRHAFSKFGGNMGTDGSVAFMFDHVGQFLFAPGTSEDALMEAALEAGANDVNTNDDGSIEVLCDWQAFSAVKDALEAGGFKAELAEVTMKPQNEVEFTGDDAAKMQKLLDALENLDDVQDVYTNAVIVEE
What are the official names of this protein?
Probable transcriptional regulatory protein Bcep18194_A5621.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA_CAMFF
Sequence: MDYLEIKGGKKLFGSVYISGAKNAALPLIAMSILAKNDVVIRNIPQVADIKTLIKLLQNLGAVSKFENLDLVINTTTINSTKATYDIVRKMRASILVLGPLLARFGHCEVSLPGGCAIGARPIDLHLSALEKMGANIEIKDGYVIARAKDGLKGANIIFDKITVTGTENIVMAAALARGTTKILNAAKEPEVVQVCQILNDSGIKIEGIGTNELTIYGGGGELLNLNKICVIPDRIEAGTYLCAAAIAGGEITLKQVEPNHLVSVLGKLSDMGVNFELGDKSIKVISDAKLSPVQIITTEFPGFPTDMQAQFMALACVANGVSTIDERLFENRFMHASELNRMGADIKLNGHIATVSGVSLNGADVMATDLRASSALVLAALVANGTTRVHRIYHLDRGYENLEIKLQSLGADIKRLSE
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP8_RHEAM
Sequence: MPQLNPNPWFFIMIMSWAVFLLLIQPKLLSFTHTNLPSNKPLSTPNPTPWTWPWT
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: P30_TOXGO
Sequence: MSVSLHHFIISSGFLTSMFPKAVRRAVTAGVFAAPTLMSFLRCGVMASDPPLVANQVVTCPDKKSTAAVILTPTENHFTLKCPKTALTEPPTLAYSPNRQICPAGTTSSCTSKAVTLSSLIPEAEDSWWTGDSASLDTAGIKLTVPIEKFPVTTQTFVVGCIKGDDAQSCMVTVTVQARASSVVNNVARCSYGADSTLGPVKLSAEGPTTMTLVCGKDGVKVPQDNNQYCSGTTLTGCNEKSFKDILPKLTENPWQGNASSDKGATLTIKKEAFPAESKSVIIGCTGGSPEKHHCTVKLEFAGAAGSAKSAAGTASHVSIFAMVIGLIGSIAACVA
What are the official names of this protein?
Major surface antigen p30.
What are the subcellular locations of this protein?
Parasitophorous vacuole. Note=Surface of extra- and intracellular tachyzoites and also component of the vesicular network within the parasitophorous vacuole.
Protein: GCSP_PROMA
Sequence: MRNTKASKFSDRHLGLIEEAQVEILNALGHADINDFISSVVPEEILDAQPPDELLPKALNEIEALEELRSIAKKNQIKRSLIGLGYYGTYTPAVIQRHVFENPAWYTSYTPYQAEIAQGRLEALFNFQTLITELTGLPIANASLLDEGTAAAEAMSLSFAVNKQTKARKFIVDDQVLPQTLAVLKTRAEPLELDIEVVNLTDLVINETVFGLLIQLPGKSGQLWDPSSLIAQAHEFNALVTVAIDPLAQVLIAPMGQLGVDIAIGSSQRFGVPIGFGGPHAAFFAIKEEYKRLVPGRLVGQSIDSKGHSALRLALQTREQHIRRDKATSNICTAQALLATIASFYAVYHGPHGLEEIAKNIIYLRSQLELYLKEFGYTFAPDCRFDTLEIHCLEAPEIHRLSILSGFNLRILPLGASIEKSKGFAVSFDELSTTKELYKLCKIFADVKDKNFEPRENTNFNFKESLTSLPLRTTPWLKQQVFNNYRTETELMRYIQKLASRDFSLVNGMIPLGSCTMKLNATAELLPITWKEFSSIHPFVPSDQAKGYGYLSEQLEGWLCALTGFDGVSLQPNAGSQGEFAGLLVIRAWHKAINQADRNICLIPKSAHGTNPASAVMAGFKVVAVECDEYGNIDFEDLVLKVETYSSELGALMITYPSTHGVFEPNIRQICDQVHLHGGQVYLDGANLNAQVGLCRPGAFGADVCHLNLHKTFCIPHGGGGPGIGPIAVAKHLVAFLPSKNFHASDNNAAIGAISASPLGSASILPISWMYIRMMGADGLRQASSLAILSANYIANKLDPYFQVLFKAPNGKVAHECILDLRSIKRITGIEVDDVAKRLMDYGFHAPTISWPVAGTLMIEPTESESFEEINRFCEAMISIRSEIDAIESGITDLSNNPLRLAPHTMETVTAEIWDRPYTRQQAAFPLKDQFMNKFWPAVSRIDNAFGDRNLVCSCSTLEELSET
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: MICU1_MOUSE
Sequence: MFRLNTLSALAELAVGSRWYHGASQPTQTKRRLMLVAFLGASAVTASTGLLWKKAHAESPPCVNSKKPDTEDKERNKDSGEVSSREGRAADAAAEPYPEDKKKKRSGFRDRKVMEYENRIRAYSTPDKIFRYFATLKVINEPGETEVFMTPQDFVRSITPNEKQPEHLGLDQYIIKRFDGKKIAQEREKFADEGSIFYSLGECGLISFSDYIFLTTVLSTPQRNFEIAFKMFDLNGDGEVDMEEFEQVQSIIRSQTSMGMRHRDRPTTGNTLKSGLCSALTTYFFGADLKGKLTIKNFLEFQRKLQHDVLKLEFERHDPVDGRISERQFGGMLLAYSGVQSKKLTAMQRQLKKHFKDGKGLTFQEVENFFTFLKNINDVDTALSFYHMAGASLDKVTMQQVARTVAKVELSDHVCDVVFALFDCDGNGELSNKEFVSIMKQRLMRGLEKPKDMGFTRLMQAMWKCAQETAWDFALPK
What is the function of this protein?
Key regulator of mitochondrial calcium uniporter (MCU) that senses calcium level via its EF-hand domains (PubMed:24560927).  MICU1 and MICU2 form a disulfide-linked heterodimer that stimulates and inhibits MCU activity, depending on the concentration of calcium (PubMed:24560927).  MICU1 acts both as an activator or inhibitor of mitochondrial calcium uptake (By similarity).  Acts as a gatekeeper of MCU at low concentration of calcium, preventing channel opening (By similarity).  Enhances MCU opening at high calcium concentration, allowing a rapid response of mitochondria to calcium signals generated in the cytoplasm (PubMed:24560927).  Regulates glucose-dependent insulin secretion in pancreatic beta-cells by regulating mitochondrial calcium uptake (By similarity).  Induces T-helper 1-mediated autoreactivity, which is accompanied by the release of IFNG (By similarity).
What are the official names of this protein?
Calcium uptake protein 1, mitochondrial, Calcium-binding atopy-related autoantigen 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the MICU1 family. MICU1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein. Mitochondrion intermembrane space. Note=The topology is subject to debate.
Protein: KN7G_ORYSJ
Sequence: MASRHRRGAFPAGAKAAPEAEAAKESVAVAVRFRPLSPREVRRGEKIAWYADGETVARSEQSNLAYAYDRVFGPTTTTRHIYDAVAQYVVNGAMKGINGTIFAYGVTSSGKTHTMHGDQISPGVIPLAVKDIFNIIQETPNREFLLRVSYLEIYNEVVNDLLNPAGQNLRIREDLQGTIVEGIKEEAVLSPVHALSLIAAGEELRHVGSTNFNLLSSRSHTIFTLTIESSPRGQSNEAEAVTLSQLNLIDLAGSESSRVETAGVHQKEGSYINKSLLTLGKVISKLTDEKATHIPFRDSKLTRLLKSSLSGQGRVSLICTVTPASSNSEETHNTLKFAHRAKHIEIQATQNKIMDARSLIKKYQNEIRQLKEELEQLRRSIRTGTPIEDTMQKKHHLLETKEDCNVKLQSRLEQGEEAKAALLERIEHLTELILVSAKASRTTKSSHCPRRRHSFGEEELAYLPYERQDIILDNESNMLFVPIEGFGEKFKSSPKEETENQKGHLNWLNLRKCDSGSTNLTSSDGENPSSTKSLPALSTPLGIGFFNVTSEQRMSDYMLAENVPANLLCVGHREFPSDSLPVQETPLVSRKTSDHVDILREQFNILSGEVALHQSVLKRLSEEAGKNAMNEQIEMEMKVVNDEVKLNKQKIASLERRISNSMSNSRGMHDNLELSLPYIEIPEQLNEKAFQLEASECQEFLLSERTTFQHNTGIVQETGSQAHKGKPLPSDVSDEFLKKASQAEIDELKQRVSELTEAKSQLDSCNHKLLEESTYAKGLASVTSVELKALSVKVTKLMKQNERLSSELASGRNQRRGSHGPRGARRESHTKRYEPARRGDMNALEAMLKEKDQRQAELHTKIEESKQKEAFLEKELANMWTVLANLKKTRGIDQEDFDSKYNGSWA
What are the official names of this protein?
Kinesin-like protein KIN-7G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-7 subfamily.
Protein: YAAA_ECOHS
Sequence: MLILISPAKTLDYQSPLTTTRYTLPELLDNSQQLIHEARKLTPPQISTLMRISDKLAGINAARFHDWQPDFTPENARQAILAFKGDVYTGLQAETFSEDDFDFAQQHLRMLSGLYGVLRPLDLMQPYRLEMGIRLENARGKDLYQFWGDIITNKLNEALAAQGDNVVINLASDEYFKSVKPKKLNAEIIKPVFLDEKNGKFKIISFYAKKARGLMSRFIIENRLTKPEQLTGFNSEGYFFDEASSSNGELVFKRYEQR
What are the official names of this protein?
UPF0246 protein YaaA.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: AROQ_YERPE
Sequence: MSDKFHILLLNGPNLNLLGTREPEKYGYTTLAEIVSQLEIQAQGMDVALSHLQSNAEHALIDSIHQARGNTDFILINPAAFTHTSVALRDALLGVQIPFIEIHLSNVHAREPFRHHSYLSDIAVGVICGLGADGYNFALQAAVNRLSKSN
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: S10AC_BOVIN
Sequence: MTKLEDHLEGIINIFHQYSVRVGHFDTLNKRELKQLITKELPKTLQNTKDQPTIDKIFQDLDADKDGAVSFEEFVVLVSRVLKTAHIDIHKE
What is the function of this protein?
S100A12 is a calcium-, zinc- and copper-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response.  Its pro-inflammatory activity involves recruitment of leukocytes, promotion of cytokine and chemokine production, and regulation of leukocyte adhesion and migration.  Acts as an alarmin or a danger associated molecular pattern (DAMP) molecule and stimulates innate immune cells via binding to receptor for advanced glycation endproducts (AGER).  Binding to AGER activates the MAP-kinase and NF-kappa-B signaling pathways leading to production of pro-inflammatory cytokines and up-regulation of cell adhesion molecules ICAM1 and VCAM1.  Acts as a monocyte and mast cell chemoattractant.  Can stimulate mast cell degranulation and activation which generates chemokines, histamine and cytokines inducing further leukocyte recruitment to the sites of inflammation.  Can inhibit the activity of matrix metalloproteinases; MMP2, MMP3 and MMP9 by chelating Zn(2+) from their active sites (By similarity).
What are the official names of this protein?
Protein S100-A12, Calcium-binding protein in amniotic fluid 1, CAAF1, Calgranulin-C, CAGC, Cornea-associated antigen, CO-AG, Extracellular newly identified RAGE-binding protein, EN-RAGE, RAGE-binding protein, S100 calcium-binding protein A12.
What is the protein family that this protein belongs to?
Belongs to the S-100 family.
What are the subcellular locations of this protein?
Secreted. Cytoplasm. Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein. Note=Predominantly localized in the cytoplasm. Upon elevation of the intracellular calcium level, translocated from the cytoplasm to the cytoskeleton and the cell membrane. Upon neutrophil activation is secreted via a microtubule- mediated, alternative pathway (By similarity).
Protein: ALY1_SCHPO
Sequence: MYIPNLRNYHDKVFPYGPSSNGYNPVIRLTDRTTQPDPSQHIYQEEKISKCEGLSYRAREWLLLSSNSNARVAIALAEPVLYLPGATSSEIQSEHSAVLRGSLCIQIYKPVKLKKIQLSFKGKSRTEWPEGIPPKLFDTYEENSIMNHCWVFFHSEQKVDENSHGAVWYKVLPHYADTAHYPRSMECFYPGEYVYNFELPISCTYPESIQTDMGRVYYFLETLVDRSSTFSGKSTGRIPIELIRSPCSTSVATSEPILVSKSWEDRLHYEVQVGEKCVVMGQVVPVNFKFTLLGEVKFHKLRLFLMERRYYYCRQRSVRRKEKTRQLLLYERSAPKNQCLLSDWKQVRPDVYELSDQVRIPGCHDMAANIVHFDTTYPNIKITHTVRTVLRFSCENSPELMGSAKYLEIYIDSPVRLLSCRCSDGSTMLPAYCPIIPSSEVNFCSIDNRIIAGMNRDLALDSDIIGNSPPSFDSWTAVPYQAPPPKYDDIFQSGSSHDENHDDN
What is the function of this protein?
May regulate endocytosis in response to extracellular stimuli.
What are the official names of this protein?
Putative arrestin-related trafficking adapter SPBC839.02.
What is the protein family that this protein belongs to?
Belongs to the ALY1 family.
Protein: SFSA_SACD2
Sequence: MKFEYPLIPATLLRRYKRFLADVELSDGSTITVHCPNTGSMRNCIVENSPCWLLDSANPKRKYRYSLERVTTPTGAVAGINSASANGLVIAAIENGVISELQGYDELAREQRYGDEKSRIDILLSKPEEQCYIEVKSVTLEEGKGEGFFPDAVSTRGQKHLRELMAMRSQGHRAVLFFCVQHSGITKVAAAEHIDPAYAALFKQAVNEGVEVIAYGVDLGIEGSVITKKLKVV
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: SP0A_CLOAB
Sequence: MESRKISVLIADDNKEFCNILNDYLLNQSDMIVVGIAKDGVEALKLIENKKPDLVVLDIIMPRLDGLGVLEKLNNKDAENLPRIIVLSAVGQDKITQRAITLGADYYVVKPFDMDVFTNRIREMFNNTISNSEQKRSYQVEEKEASFAGTIANDVYSDNIGNKAVDLESEITSIIHQIGVPAHIKGYMYLREAITMVVNNMELLSAVTKELYPSIAKKYNTTASRVERAIRHAIEVAWSRGQVETINKLFGYTINNGKGKPTNSEFIAMIADKLRLKNKVS
What is the function of this protein?
May play the central regulatory role in sporulation.  It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress.  Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process (By similarity).
What are the official names of this protein?
Stage 0 sporulation protein A homolog.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RT13_ARATH
Sequence: MLGLRRSATTLFDISQSLLRNVTFHGLRVQGIRVGNAEVPNNKPLKTGLQEVYGIGRRKSHQVLCHLGITNKLARDLTGKELIDLREEVGQHQHGDELRRRVGSEIQRLVEVDCYRGSRHRHGLPCRGQRTSTNARTKKGKAVAIAGKKKAPRK
What is the function of this protein?
Located at the top of the head of the small subunit, it contacts several helices of the 18S rRNA.
What are the official names of this protein?
Small ribosomal subunit protein S13, mitochondrial, mS13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: Y3063_BACAN
Sequence: MKIYVDADACPVKDVIIFEATKAEIPVILVTSFSHYSNAEQPKGVETIYVDSGADAADYRIMQLAQKEDLIVTQDYGLASLALAKGCIVLHHKGYKYTNENIEQLLQTRYLSAMVRKSGKRTKGPKPFTAEDKEKFRALFKSMIAL
What are the official names of this protein?
UPF0178 protein BA_3063/GBAA_3063/BAS2849.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: 3O1D_RHOOP
Sequence: MQDWTSECDLLVVGSGGGALTGAYTAAAQGLTTIVLEKTDRFGGTSAYSGASIWLPGTQVQERAGLPDSTENARSYLRALLGDAESERQDAYVETAPAVVALLEQNPNIEFEFRAFPDYYKAEGRMDTGRSINPLDLDPADIGDLAGRCVRNCTKTDRMDHAPGRMIGGRALIAVSAAVQSTARQNFAPESVLTSLIVEDGRVVGGLRSNPRYRQRIKANRGVLMHAGGGFEGNAEMREQAGTPGKAIWSMGPSGPTPATRSPPELAGRRRNSLARSGVVLPRGRAARRRRLHGRVRGGLVVDSPGSVPQRVASVRPVRTSHGCSPDDNGSAVPSFMIFDSREVTDCPPSASRTRPPPSTSKPEPGSVPTLSKNSLPRPDYRPERIAQHCRKVQRCRKLGVDEEFHRGEDPYDAFFCPPNGGANAALTAIENGPFYAARDRLSDLGTKGGLVTDVNGRVLRADGSAIDGLYAAGNTSASVAPFYPGPGVPLGTAMVFSYRAAQDMAK
What is the function of this protein?
Catalyzes the elimination of the C-1 and C-2 hydrogen atoms of the A-ring from the polycyclic ring structure of 3-ketosteroids.
What are the official names of this protein?
3-oxosteroid 1-dehydrogenase, Steroid 1:2-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase 2 family. 3-oxosteroid dehydrogenase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RR4B_CYACA
Sequence: MSRYLGPRVRVIRRLGALPALTNKSPKKRTIAPGEHAHKTRKLSEFAVQLQEKQKLQYYYGITNSQLARYFRQARRSKSSTGLALLTMLETRLDHLVYRAGFAPTLPAARQLVNHGHVKVNGKKVTIASWACEVNHVIEVKSSSPPKPPEYLPPYLQLSNGTLTVTQPVQKEWLAFVVNELLVVEYYTRVGA
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: VPC10_MYCTO
Sequence: MILVDSDVLIAHLRGVVAARDWLVSARKDGPLAISVVSTAELIGGMRTAERREVWRLLASFRVQPATEVIARRAGDMMRRYRRSHNRIGLGDYLIAATADVQDLQLATLNVWHFPMFEQLKPPFAVPGHRPRA
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  An RNase.  The cognate antitoxin is VapB10 (By similarity).
What are the official names of this protein?
Ribonuclease VapC10, RNase VapC10, Toxin VapC10.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: PPE47_MYCTO
Sequence: MTAPVWLASPPEVHSALLSAGPGPGSLQAAAAGWSALSAEYAAVAQELSVVVAAVGAGVWQGPSAELFVAAYVPYVAWLVQASADSAAAAGEHEAAAAGYVCALAEMPTLPELAANHLTHAVLVATNFFGINTIPIALNEADYVRMWVQAATVMSAYEAVVGAALVATPHTGPAPVIVKPGANEASNAVAAATITPFPFGELAKFLEMAAQAFTEVGELIMKSAEAWAVGFVELITGLVNFEPWLVLTGMIDMFFATVGFALGVFVLVPLLEFAVVLELAILSIGWIISNIFGAIPVLAGPLLGALAAAVVPGVAGVTGLAGLAAVPAVGAAAGAPAALVGSVAPVSGGVVSPQARLVSAVEPAPASTSVSVLASDRGAGALGFVGTAGKESVGQPAGLTVLADEFGDGAPVPMLPGSWGPDLVGVAGDGGLVSV
What are the official names of this protein?
Uncharacterized PPE family protein PPE47/PPE48.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PPE family.