PharMolix/UniProtQA huggingface dataset:
Protein: PYRD_MARMS
Sequence: MYQLARSLLFKLDPEVSHELSLDLLAASSRLGLNRFLGGLPSTKPVDVMGLRFPNAVGLAAGLDKNADAFEALGALGFGFVEVGTVTPKGQAGNPKPRLFRLPEHEAIINRMGFNNKGVDHLVSRIKSHRYPGVLGVNIGKNLTTSVEDAAADYLACLESVIPYADYITANISSPNTPGLRSLQFGESLAQLIAPLVAARDRYEAAYGKRVPLAVKIAPDMTDDEIKMVADTLVDQGVDGIIATNTTLSREAVLGHQFEKEAGGLSGMPVRDASTHVVKVLAEHLKDTLPIIGVGGISSGADAVEKLQAGARLVQIYSGFIYHGPELIKEAVASTDAYYRELDLGI
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ARNB_YERPS
Sequence: MQSFLPFSRPAIGSEEINAVANVLGSGWITTGPQNHQLETDFCQIFGCKHAIAVCSATAGMHITLLALGIGPGDEVITPSQTWVSTINMIVLLGAEPVMVDVDRDTLMVNAAAIEAAITPNTKAIIPVHYAGAPCDLDALRQISQRHGIPLIEDAAHAVGTRYRDQWIGEQGTAIFSFHAIKNITCAEGGLVATDDDELAARVRRLKFHGLGVDAFDRQIQGRSPQAEVVEPGYKYNLSDIHAAIAVVQLRRLPEINARRQALVASYHKALAHLPLQPLALPHYSHQHAWHLFMVRVDEERCGISRDQLMACLKDMGIGSGLHFRAVHSQKYYRERYPHLCLPNTEWNSARLCTLPLFPDMLDSDIERVANALTTIIGSHRVTK
What is the function of this protein?
Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase, UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase, UDP-Ara4O aminotransferase, UDP-4-amino-4-deoxy-L-arabinose aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.
Protein: HOP2_XENLA
Sequence: MSKSKEAAASSIILKYLNDQNRPYSTQDVFSNLQRDHGLGKTAVVKTMELLAQKGKIKEKVYGKQKIYFADQEQFPSVSDSELKDLDAQVTELSSKLQSSQQSCRQLESELKDLTSSLTTEEMLKEVSCLKEECDRHEHKLTNIKSATNHVTPAEKEKVYGERKHFCKEWKKRKRMATDIFDAILEGYPKSKKQFFEEVGVETDEDCNVTVPDV
What is the function of this protein?
Plays an important role in meiotic recombination.  Stimulates DMC1-mediated strand exchange required for pairing of homologous chromosomes during meiosis (By similarity).
What are the official names of this protein?
Homologous-pairing protein 2 homolog, PSMC3-interacting protein, Proteasome 26S ATPase subunit 3-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the HOP2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYDP_SHIF8
Sequence: MDDLTAQALKDFTARYCDAWHEEHKSWPLSEELYGVPSPCIISTTEDAVYWQPQPFTGEQNVNAVERAFDIVIQSTIHTFYTTQFAGDMHAQFGDIKLTLLQTWSEDDFRRVQENLIGHLVTQKRLKLPPTLFIATLEEELEVISVCNLSGEVCKETLGTRKRTHLASNLAEFLNQLKPLL
What is the function of this protein?
Interacts with the SecY protein in vivo.  May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.
What are the official names of this protein?
Protein Syd.
What is the protein family that this protein belongs to?
Belongs to the Syd family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Loosely associated with the cytoplasmic side of the inner membrane, probably via SecY.
Protein: SSRP_GRABC
Sequence: MAETKSGKSGLISHGVAAQNRKARFDYTIKETVEAGLVLKGPEVKSLRHGRATLSEAWAGERDGEMFLFNAYIPEYQGGVLSRFEPRSPRKLLLKRKQINHLLGAVQKQGQTVVPLQIHFNERGMAKVLLGVAEGRNKADKRAAIASRDWQRDKARLMREKG
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: STS2_HUMLU
Sequence: MSTQIFASSSQNEKIHKILRPTKKLQPSVWGERFLHYNISEQELRYKQQQVEELKAVVKKEIFGESAYDVSHQLKLINVVERLGLSYHFESEIENELESIYNKSVDQNYILKDENLHDASLRFRLLRQHGFRVSSADIFEKFKDEDGNFKECLVSDTIGLLSLYEASHLSCVGENILDEALDFTTTHLTEFLANKKEHDDPLSKEISQALERPLRKSLERLAARHFISIYANETSHNKVLLQLAKLDFNLLQSIHKKELSEISRWWKESDFVHKFPFARDRIVELYLWILAVYYEPQYYLARNILTKTIALASIADDIYDEYGTIEELELLTEAVERWDINFIDKLNPEYLQTFYKELLNSYEEFEQALSKEETYRVHYAKERFKELLRSSLEVAWWLKEGRVPSFDEYLKISLINCGYHMLIVSSLIGMKGSIVTKEVFEWLSIDRKIVRASVTICRLMDDIAEYKFEQEKNEEPSAVECYMKQYGVSEEEAYDELNKRVVNAWKEINEELLKPTGVASPILVRALNFSKFMDLFYKNGDGYTQVGKVTKHSVAALLIHPIP
What is the function of this protein?
Sesquiterpene synthase that catalyzes the formation of germacrene A.  Can use farnesyl diphosphate as substrate, but not geranyl diphosphate or geranylgeranyl diphosphate.  Beta-elemene, the initially measured product in the assay, is derived nonenzymatically from germacrene A.
What are the official names of this protein?
Germacrene-A synthase, Sesquiterpene synthase STS2, HlSTS2.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsa subfamily.
Protein: MURD_NOVAD
Sequence: MIVSRAFAGKRYAVLGLARSGLASVESLLAGGADVTVWDNREEPRSAFEGSCTIADPLSIDLTGFAGVVVSPGVPLNRHPIADHARAAGVPVIGDIELFAQARADLPPHRVVGITGTNGKSTTTMLVHHICAAAGLPARLGGNIGLPILGQEPLPEGGVYVLELSSYQIDLTQSLACDVAALINLSPDHLDRYDGFAGYAASKARLFAMQRADQHAVFGCGDEHTLEIAREASATHDTGFVHVVQPSALHGQLEWPSLQGPHNLQNAAIAVEIARQLGIAEDIWRSALASFVGLPHRMERVAEANGVLFVNDSKATNPASTAPALGAYPRIHWILGGLPKSDNLDECAPYFDHVVAAYTIGEAGPRFAEILEPVMPVTRSEMLCDAVRQAMEAAQPGDVVMLSPACASFDQFRDFEARGDSFRQIVEALIEDREAPCPDGTPT
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIRO1_ARATH
Sequence: MARYAAGAVDCPGSPKSVRIVVVGDKGTGKSSLIVAAATDSFPPNVPPVLPDYKLPIEFFPDGIPVTIVDTSSRPEDRDIVAEELKRADAVVLTYACDRPETLERLSEYWLPELRRLEVKIPIIVAGCKLDFRDDNNQVSLEQVMSPIMQQFREIETCIECSALKQLQAQEVFYYAQKTVLHPTGPLFDQDSQALKPRCVRALKRIFILCDHDRDGALSEAELNDFQVKCFHAPLQPSEIEGVKRVVQEKLPEGVNERGLTVTGFLFLHALFIEKGRLETTWTVLRKFGYNNDIRLAEELLPSAIFKRAPDQSFELTNAAIDFLKGMYMLFDDDQDNNLRPQEIEDLFSTAPESPWKEAPYEDAAEKTALGGLSFDAFLSMWSLMTLLEPARSVENLIYIGFPGDPSTAIRVTRRRRLDRKKQQCERKVFQCFVFGPNNAGKSALLNCFLGRSYTDNQESTTDERYAVNMVDESGAKKTLIMREIPEDGVQGLFSSKESLAACDIAVFVYDSSDESSWKRATQLLVEVANYGEATGYEVPCLMVSAKDDLDSSPISIQESTRMTQDMGIEPPVSISSKLGDFNNLFRKILTAAQHPHLSIPETEAGKSRKHYNRLINRSLMAVSIGAAAVVVGLAAYRVYATRKSSSA
What is the function of this protein?
Mitochondrial GTPase required to maintain proper development, morphology and intracellular distribution of mitochondria, which in turn are essential for the progress of embryonic cell division, development of haploid male and female gametes, and pollen tube growth.
What are the official names of this protein?
Mitochondrial Rho GTPase 1, AtMIRO1, Miro-related GTPase 1.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial Rho GTPase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass type IV membrane protein.
Protein: HGL1A_WHEAT
Sequence: MALLAAATLNPTTHLSLRSRAGRNSENLWLRSAASSQKSKGRFCNLTIRAGTPSKPAEPIGPVFTKLKPWQIPKRDWFDKDFLFGASTSAYQIEGAWNEDGKGPSTWDHFCHTYPERISDRTNGDVAANSYHLYEEDVKALKDMGMKVYRFSIAWSRILPDGTGKVNQAGIDYYNKLINSLIDNDIVPYVTIWHWDTPQALEDKYGGFLNRKIVDDYKQFAEVCFKNFGDRVKNWFTFNEPHTYCCFSYGEGIHAPGRCSPGMDCAVPKGDSLREPYTAGHHILLAHAEAVELFKACYNKHGDSKIGMAFDVMGYEPFQDSFLDDQARERSIDYNLGWFLEPVVRGDYPFSMRSLIGDRLPKFTKEEQEKLASSCDIMGLNYYTSRFSKHIDISSDFTPKLNTDDAYASSETKGSDGNDIGPITGTYWIYMYPKGLTDLLLIMKEKYGNPPIFITENGIADVDSDPTMTDPLDDWKRLDYLQRHISAVKDAIDQGADVRGHFTWGLIDNFEWSLGYSSRFGLVYIDKKDGNKRKLKKSAKWFAKFNSVPKRLLKTTNNNATVTVTSVSV
What is the function of this protein?
Acts in defense of young plant parts against pests via the production of hydroxamic acids from hydroxamic acid glucosides.  Enzymatic activity is highly correlated with plant growth.  The preferred substrate is DIMBOA-beta-D-glucoside.
What are the official names of this protein?
4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1a, chloroplastic, Beta-glucosidase 1a, TaGlu1a.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y1874_STAA1
Sequence: MNDQWYKHLIGARTIKTGIAIFLTAVFCMALDLTPIYAILTAVVTIEPTAKASLIKGYRRLPATVIGAGFAVLFTYLFGDQSPFTYALSATFTILFCTKLKLQVGTNVAVLTSLAMIPGIHDAYIFNFLSRTLTAIIGLVTSGLINFMVFPPKYYGQVEEKLSKTDALMYKLFYNRCQELILSRLQSDKSEKAYKNIFNLNNQVETLISYQRDELSYHKKKECDWKLLNQLTKRAYTNRLFITHLSNIIYLPKNTRVNFSGDEKMALLKISSSIKDIFYDGTFKREDDSVETLRSTIKALEISGENQIKSHILYEVLMIYRLLDSRYA
What are the official names of this protein?
UPF0421 protein SAHV_1874.
What is the protein family that this protein belongs to?
Belongs to the UPF0421 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y501_HYDS0
Sequence: MAGHSHWAQIKHKKAKVDAQKGKLFGKLIREITVATKLGGPDPNANPRLRIAIEAARKVSMPMDTIEKAIKRGTGNDKEGALEEIVYEGYGPGGTAIMVVVATDNRNKATSEVRHAFSKHGGNLGSSGCVSYLFEQKGVIEIPKEATDEEKLMEAALEAGADDVESTEDMFIVYTNPKDVYTIKDILASKGFTIESAKTSLIPTTTVEIKDVDTAKKLLNLLEHLDELDEVQEVISNFEIDKDILAALG
What are the official names of this protein?
Probable transcriptional regulatory protein HY04AAS1_0501.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTC_ECO55
Sequence: MKFFALFIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVSEMTSSSSLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSRPTYRKANPSDAPIMILTLTSDTYSQGELYDFASTQLAPTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRTAISNANVRKPQGALEDGTHRWQIQTNDELKTAAEYQPLIIHYNNGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDSIRAKLPELQETIPAAIDLQIAQDRSPTIRASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENIARHLEAGMKPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLLVSLTLTPMMCGWMLKASKPREQKRLRGFGRMLVALQQGYGKSLKWVLNHTRLVGVVLLGTIALNIWLYISIPKTFFPEQDTGVLMGGIQADQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTGGSRVNSGMMFITLKPRGERSETAQQIIDRLRVKLAKEPGANLFLMAVQDIRVGGRQSNASYQYTLLSDDLAALREWEPKIRKKLATLPELADVNSDQQDNGAEMNLVYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGLSAASTISFNLPTGKSLSDASAAIDRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVILIIAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRHGNLTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLRFSRKPKQTVTE
What is the function of this protein?
The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate.
What are the official names of this protein?
Multidrug resistance protein MdtC, Multidrug transporter MdtC.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HISZ_AGRVS
Sequence: MPLINMPDFAGALLDDFAARGAARVDTPVIQPAEPFLDMAGEDLRRRIFLTESETGESLCLRPEFTIPVCLSHIENATGTPKRYAYLGEVFRQRREGGNEFYQAGIEDLGEPATARADARAINDAIGILHKLLPGRPLTVMLGDQAVFEAVVKTLGLPSGWQRRLIQAFGDSTHLDQLLKTLASPQTAHGLDPAVEALLSSGDEAGLIAHLDRTMEDTGYSTNASRSPREIAARLKEKLALAETRLDGAALLLLREFLSLELPLSEATAALAGFADAAGLSLGAALDGFEARIAALADLGVDLSRITYRAAFGRPLDYYTGLVFEVALSGETAVLAGGGRFDRLLTLLGAKHTIPAVGFSLWLDRIELARAR
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GDA7_WHEAT
Sequence: MKTFLILALVATTATTAVRVPVPQLQPKNPSQQQPQEQVPLVQQQQFPGQQQQFPPQQPYPQPQPFPSQQPYLQLQPFPQPQPFLPQLPYPQPQSFPPQQPYPQQRPKYLQPQQPISQQQAQQQQQQQQQQQQQQQQQILQQILQQQLIPCRDVVLQQHNIAHASSQVLQQSTYQLLQQLCCQQLLQIPEQSRCQAIHNVVHAIIMHQQEQQQQLQQQQQQQLQQQQQQQQQQQQPSSQVSFQQPQQQYPSSQGSFQPSQQNPQAQGSVQPQQLPQFAEIRNLALQTLPAMCNVYIPPHCSTTIAPFGIFGTN
What is the function of this protein?
Gliadin is the major seed storage protein in wheat.
What are the official names of this protein?
Alpha/beta-gliadin clone PW8142, Prolamin.
What is the protein family that this protein belongs to?
Belongs to the gliadin/glutenin family.
Protein: PEP1_THUOR
Sequence: LLQVPLEKGQSAREYLQEQGLWEQYRLKYPYNPMAKFDPSFAVAGEPMTNDADLAYYG
What are the official names of this protein?
Pepsin-1.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
Protein: ACKA_DESHD
Sequence: MKILVINCGSSSLKYQLLDMDTQTPIAKGLVERIGLPGAVLTHRPADGEKEIITAEIPNHTVAIQLVLDALVNPEYGVVKSLEEIGSVGHRVVHGGEKFASSVLITDEVMQAIEECIELAPLHNPPNIAGIEACQKLMPGVPQVAVFDTAFHQTMPPHAYLYGLPYEFYEKYKIRKYGFHGTSHKYVSQRAAKLLNRPAEGLKLISCHLGNGSSITAIKDGKSIETSMGFTPLEGLMMGTRSGDLDPAIVSFIQQKENLSSDEVNDFLNKKCGVLGLSGVSSDFRDIEQARDQGNYRAALALDVFSHDVKKYIGSYAAVLNGADAIIFTAGLGENSAEMREAVVDGLQYLGAKLDLEKNKVRGKEADISAPEATCRVLVIPTNEELMIALDTLDIIQKG
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMA_CAUVN
Sequence: MPTLVLLRHGQSQWNLENRFTGWVDVDLTAEGEAQARKGGELIAAAGIEIDRLFTSVQTRAIRTGNLALDAAKQSFVPVTKDWRLNERHYGGLTGLNKAETAEKHGVEQVTIWRRSYDIPPPELAPGGEYDFSKDRRYKGASLPSTESLATTLVRVLPYWESDIAPHLKAGETVLIAAHGNSLRAIVKHLFNVPDDQIVGVEIPTGNPLVIDLDAALKPTGARYLDDSRAEALPKVG
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: ORN_SALTI
Sequence: MSADENNLIWIDLEMTGLDPERDRIIEIATLVTDASLNILAEGPTIAVHQSDAQLALMDDWNVRTHTGSGLVDRVKASTMGERDAELATIEFLKTWVPAGKSPICGNSIGQDRRFLFKYMPELEAYFHYRYLDVSTLKELARRWKPEILAGFTKQGTHQAMDDIRESVAELAYYREHFIKL
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: D4FAD_THRSP
Sequence: MTVGYDEEIPFEQVRAHNKPDDAWCAIHGHVYDVTKFASVHPGGDIILLAAGKEATVLYETYHVRGVSDAVLRKYRIGKLPDGQGGANEKEKRTLSGLSSASYYTWNSDFYRVMRERVVARLKERGKARRGGYELWIKAFLLLVGFWSSLYWMCTLDPSFGAILAAMSLGVFAAFVGTCIQHDGNHGAFAQSRWVNKVAGWTLDMIGASGMTWEFQHVLGHHPYTNLIEEENGLQKVSGKKMDTKLADQESDPDVFSTYPMMRLHPWHQKRWYHRFQHIYGPFIFGFMTINKVVTQDVGVVLRKRLFQIDAECRYASPMYVARFWIMKALTVLYMVALPCYMQGPWHGLKLFAIAHFTCGEVLATMFIVNHIIEGVSYASKDAVKGTMAPPKTMHGVTPMNNTRKEVEAEASKSGAVVKSVPLDDWAVVQCQTSVNWSVGSWFWNHFSGGLNHQIEHHLFPGLSHETYYHIQDVFQSTCAEYGVPYQHEPSLWTAYWKMLEHLRQLGNEETHESWQRAA
What is the function of this protein?
Fatty acid desaturase that introduces a cis double bond at the 4-position in 22-carbon polyunsaturated fatty acids that contain a Delta(7) double bond, resulting in the production of delta-4 desaturated fatty acid docosahexanoic acid (DHA) (22:6(4,7,10,13,16,19)).
What are the official names of this protein?
Acyl-lipid (7-3)-desaturase, Acyl-lipid 4-desaturase, Delta-4 fatty acid desaturase.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TLE4_HUMAN
Sequence: MIRDLSKMYPQTRHPAPHQPAQPFKFTISESCDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQAEIVKRLNAICAQVIPFLSQEHQQQVVQAVERAKQVTMAELNAIIGQQLQAQHLSHGHGLPVPLTPHPSGLQPPAIPPIGSSAGLLALSSALGGQSHLPIKDEKKHHDNDHQRDRDSIKSSSVSPSASFRGAEKHRNSADYSSESKKQKTEEKEIAARYDSDGEKSDDNLVVDVSNEDPSSPRGSPAHSPRENGLDKTRLLKKDAPISPASIASSSSTPSSKSKELSLNEKSTTPVSKSNTPTPRTDAPTPGSNSTPGLRPVPGKPPGVDPLASSLRTPMAVPCPYPTPFGIVPHAGMNGELTSPGAAYAGLHNISPQMSAAAAAAAAAAAYGRSPVVGFDPHHHMRVPAIPPNLTGIPGGKPAYSFHVSADGQMQPVPFPPDALIGPGIPRHARQINTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYIRSCRLLPDGRTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMENSNVEVLHVTKPDKYQLHLHESCVLSLKFAHCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIVTGSGDKKATVYEVIY
What is the function of this protein?
Transcriptional corepressor that binds to a number of transcription factors.  Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling.  The effects of full-length TLE family members may be modulated by association with dominant-negative AES.  Essential for the transcriptional repressor activity of SIX3 during retina and lens development and for SIX3 transcriptional auto-repression (By similarity).
What are the official names of this protein?
Transducin-like enhancer protein 4, Grg-4, Groucho-related protein 4.
What is the protein family that this protein belongs to?
Belongs to the WD repeat Groucho/TLE family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RUVC_HELMI
Sequence: MVILGIDPGTAICGYGLIEVQGNRLSALAYGAVRTPAHTSQASRLQTIFTDLEAIIATYRPTHVAVEELFFNRNVTTALTVGQARGVILLAAARAGLSVHEYKPSQVKQAVVGYGRAEKQQVQQMVRVLLALEEIPKPDDVADALAVAICCAHSLTWGVACR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: CPFC_MYCVP
Sequence: MSVEALLLLSFGGPEGPEQVMPFLENVTRGRGIPRERLESVAEHYLHFGGVSPINGINRDLIVAIEAELARRGMQMPVYFGNRNWEPYVEDTVAAMRDNGIRRAAVFSTSAWGGYSGCAQYQEDIARGRAAAGPEAPELVKLRQYFDHPLLIEMFADAIRDAAATLPEDLRAQARLVFTAHSIPVRAANRCGPDLYERQVAHTSALVAAAAGYPEYDQVWQSRSGPPQVPWLEPDVGDHLEVLAARGVNAVIVCPVGFVADHIEVVWDLDNELAEQAAEAGIALARASTPNAQPRFAKLVVDLIDELRLGLPPQRVGGGLVPGYGSSVNGALCTPDCSG
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
What are the official names of this protein?
Coproporphyrin III ferrochelatase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SH_MUMP1
Sequence: MPANQPPLYLTFLLLILLYLIITLYVWTILTINHKTAVRYAALYQRSCSRWGFDQSL
What is the function of this protein?
Plays a role in the inhibition of the host NF-kappa-B pathway.  This inhibition occurs at the receptor level, by preventing the signaling of TNFR1 as well as IL-1R and TLR3.
What are the official names of this protein?
Small hydrophobic protein.
What is the protein family that this protein belongs to?
Belongs to the rubulavirus small hydrophobic protein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass membrane protein. Host cell membrane; Single-pass membrane protein.
Protein: ARNC_PSE14
Sequence: MRPYPIKFVSIVIPVYNERQSLPELLRRTEAACKHLNHRFEIVLVDDGSRDDSAEILQQAAERSASPFVAVILNRNYGQHAAIMAGFEQCKGDVVITLDADLQNPPEEIPRLVALAEQGYDVVGTVRSNRQDSAWRRWPSKIINVAVQRSTGVAMSDYGCMLRAYRRTIVDAMLACRERSTFIPILANSFARHTTEVLVDHAEREHGDSKYSPMRLVNLMFDLITCMTTTPLRLLSIIGFSMALLGVLFAALLIILRLIFGAPWAGDGTFVLFAVLFVFTGGQFIGMGLLGEYLGRMYSDVRARPRFFIEKVVRSSSEVVSESVDSSVTPYMNKVAP
What is the function of this protein?
Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase, Undecaprenyl-phosphate Ara4FN transferase, Ara4FN transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DER_ACIBC
Sequence: MKPVIALIGRPNVGKSTLFNQITKSRDALVADFAGLTRDRKYGDATYQNKSFIVVDTGGIGESEGGIDNYMAEQSKTAINEADIIIFVVDARAGLLASDEQIARELRTLGKKIYLVANKVDGVHAEAALVEFYKLGMGEPLQVAASHGRGVQQMLEDVLQDIPEDENPEEHDKDTGLRLAIIGRPNVGKSTLVNRLLGEDRVVAFDQPGTTRDSIYIPFEREGRKYTLIDTAGVRRKGKVDEMIEKFSIVKTLQAMKDAHVVVVVVDAREGIVEQDLHLIGYALEAGRAMVIAINKWDNMSEYDRKQCKLDVERRFDFIPWARIHLISALHGTGVGELYPSIHRAYESANLKVSPAKLTQILNDATDQHQPPTVQGRRIKMRYAHMGGQNPPTIVIHGNKVDKTPADYRRYLENVFRKVYKLEGTPVKIEFKTSENPFEGRKSQVDERTAARRRRYIQKFKKAEKKFKR
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: RL28_HYDS0
Sequence: MAACFVCNKKAVYGKSVTFSAERNSRVFKPNLQSVKIRMPDGSTKRVMVCTKCLKAGKVVKAV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: IRAD_SHIFL
Sequence: MMRQSLQAVLPEISGNKTSLLRKSVCSDLLTLFNSPHSALPSLLVSGMPEWQVHNPSDKHLQSWYCRQLRSALLFHEPRIAALQVNLKEAYCHTLAISLEIMLYHDDEPLTFDLVWDNGGWRSATLENVS
What is the function of this protein?
Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during oxidative stress.  Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway.
What are the official names of this protein?
Anti-adapter protein IraD.
What is the protein family that this protein belongs to?
Belongs to the GpW/Gp25 family. IraD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.