PharMolix/UniProtQA huggingface dataset:
Protein: IF2G_DICDI
Sequence: MATKNKPNLSVQDVKLLNVNELTPLTPNVISRQATINIGTIGHVAHGKSTVVKAISGVLTVRFTSEFKRNITIKLGYANAKIYKCDNPQCERPGCYKSARSNTEDNPQCERPGCGGRMTLLRHVSFVDCPGHDVLMATMLNGAAVMDAALLLIAGNESCPQPQTSEHIAAIEIMNLKNIIILQNKIDLVKEAAAQEQYGQILKFIQGTIAENAPIIPISAQMKYNIDVICEYIVKKIPIPVRDFTSDPRMIVIRSFDVNKPGSRVDEIKGGVAGGSILKGVLKIGDEIEVRPGVISKELDGKIKCSPIFCRIISLFAEENELQYAVPGGLIGVGTKIDPTLCRADRLVGQVLGSVGKLPEIFVALEVNFFLLRRLLGVKSDGDKQSKVKKLSKEDTLMVNIGSTSTGCRVVAVKHDLAKLQLLTPVCSQEGEKIALSRRVDKNWRLIGWGEIKKGTVLTN
What is the function of this protein?
As a subunit of eukaryotic initiation factor 2 (eIF-2), involved in the early steps of protein synthesis.  In the presence of GTP, eIF-2 forms a ternary complex with initiator tRNA Met-tRNAi and then recruits the 40S ribosomal complex and initiation factors eIF-1, eIF-1A and eIF-3 to form the 43S pre-initiation complex (43S PIC), a step that determines the rate of protein translation.  The 43S PIC binds to mRNA and scans downstream to the initiation codon, where it forms a 48S initiation complex by codon-anticodon base pairing.  This leads to the displacement of eIF-1 to allow GTPase-activating protein (GAP) eIF-5-mediated hydrolysis of eIF2-bound GTP.  Hydrolysis of GTP and release of Pi, which makes GTP hydrolysis irreversible, causes the release of the eIF-2-GDP binary complex from the 40S subunit, an event that is essential for the subsequent joining of the 60S ribosomal subunit to form an elongation-competent 80S ribosome.  In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must be exchanged with GTP by way of a reaction catalyzed by GDP-GTP exchange factor (GEF) eIF-2B.
What are the official names of this protein?
Eukaryotic translation initiation factor 2 subunit 3, Eukaryotic translation initiation factor 2 subunit gamma, eIF-2-gamma.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
Protein: GRPE_ANOFW
Sequence: MFKGGEKMEKEQRTYDETLEQHEDAQSEQAPEEQVEQVENEATQQEEKDELTVAYEKIAQLEAKLAETENRFLRLHADFDNYRRRVRLDMEAAEKYRAQSLVSDLLPILDNFERALQVQVEDEKAKLLLQGMEMVYRSLIEALKKEGVEAIESVGKPFDPHVHQAVMQVDDQNYEPNTVVEEFQKGYKLKDRVIRPAMVKVNQ
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA2_CLOTE
Sequence: MARNVRLKVEYDGTNYSGWQKQKDKNIKTIQSSIEKAIEEATKEEVELIGSSRTDAGVHALAYTANFKTCSTIPGEKFKHALNRFLPEDIVILESEEVPMEFHSRFDCIGKTYVYKILNRPLFSPIQRNYIYHVKDELDINSMIEASKFLIGTHDFNAFKKSGGNLKTTVRTITNINILKSNDIVEIHVSGDGFLYNMVRIISGTLIEVGLSRRKPEDISIILQSKDRCKAGMCAPARGLYLKELFYN
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A 2, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I 2, tRNA-uridine isomerase I 2.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: YVIA_VACCC
Sequence: MSLIRDFSFWNRIIINIYNFIEISDNYFDHILQFEKIKSPIYYKHVQGNRCQITNGYLISIRILYYLSAKITTLDSS
What are the official names of this protein?
Uncharacterized 9.3 kDa protein.
Protein: EDIN_STAAU
Sequence: MKNKLLFKIFLSLSLALSVYSINDKIIEVSNTSLAADVKNFTDLDEATKWGNKLIKQAKYSSDDKIALYEYTKDSSKINGPLRLAGGDINKLDSTTQDKVRRLDSSISKSTTPESVYVYRLLNLDYLTSIVGFTNEDLYKLQQTNNGQYDENLVRKLNNVMNSRIYREDGYSSTQLVSGAAVGGRPIELRLELPKGTKAAYLNSKDLTAYYGQQEVLLPRGTEYAVGSVELSNDKKKIIITAIVFKK
What is the function of this protein?
Inhibits terminal differentiation of cultured mouse keratinocytes.  In culture, inhibits also the differentiation of human keratinocytes.  Probable ADP-ribosyltransferase.
What are the official names of this protein?
Epidermal cell differentiation inhibitor, EDIN.
What is the protein family that this protein belongs to?
To ADP-ribosyltransferase C3 of Clostridium.
Protein: HIS1_ANADF
Sequence: MNGEIITVAVPKGRLLEESSALFERALGVSPKRLLDGTRKLAADAPEAGLRFISIRAADVASYVEHGAAAVGIVGLDILREEPRDLYEPLDLGIGRCQVIVARHKQAKPLPRGVAPRVATKYLSLAAHHFARKGIPAEIIPLHGSIEVAPSLGLADAIVDITETGETLRANGLVIEELVLDVSARLVVNRVALKLHAERLRRLIEALRRVCAETATPKVR
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARMT1_MACFA
Sequence: MAVVPASLSGQDVGSFAYLTIKDRIPQILTKVIDTLHRHKSEFFENHGEEGVEAEKKAISLLSKLRNELQTDKPIIPLVEKFVDTDIWNQYLEYQQSLLNESDGKSRWFYSPWLFVECYMYRRIHEAIIQSPPIDYFDVFKESKEQNFYESQESVIALCTHLQQLIKTIEDLDENQLKDEFFKLLQISLWGNKCDLSLSGGESSSQKTDVLNSLEDLKPFILLNDMEHLWSLLSNCKKTREKASVTRVYIVLDNSGFELVTDLILANFLLSSELATEVHFYGKTIPWFVSDTTIHDFNWLIEQVKHGNHKWMSKCGADWEEYVKMGKWVYHDHIFWTLPHEYCAMPQVAPDLYAELQKAHLILFKGDLNYRKLTGDRKWEFSVPFHQALNGFHPAPLCTIRTLKAEIQVGLKPGQGEQLMASEPCWWTSGKYGIFQYDGPL
What is the function of this protein?
Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate (By similarity).  Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism (By similarity).  Has also been shown to have O-methyltransferase activity that methylates glutamate residues of target proteins to form gamma-glutamyl methyl ester residues (By similarity).  Possibly methylates PCNA, suggesting it is involved in the DNA damage response (By similarity).
What are the official names of this protein?
Damage-control phosphatase ARMT1, Acidic residue methyltransferase 1, Protein-glutamate O-methyltransferase, Sugar phosphate phosphatase ARMT1.
What is the protein family that this protein belongs to?
Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.
Protein: DAPAL_THEON
Sequence: MRGVIVPLVTPFNEDYSIDVPALEEHIDFLQKAGVHGIFINATTGEFTSLSVEERKFLAEKGRELVNTTFYLVGTASTNTFEVIELTKHAQDLGADYVVIAPPYYCPLNETALFRHYSMVAERTDIPIILYNIPSCANPLSVQLIKRLALEYSNIAGVKETIDSVNHVRDVIIEVKGEREDFMVFTGLDQHFLNTLILGGDGGIMACANFAPEVHLALYKAFQEKRFKDAFIYAQKLARLSKVYDLASSFGSAIKLAMSLRGFSIKPVLRPPYIIDGDEVKEEIRKLLREVLY
What are the official names of this protein?
Uncharacterized DapA-like lyase TON_0506.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTO1_SCHPO
Sequence: MLYIVDFDETITTYDTIHLLAEAVNKPEEWSVISDKYWQEYLAWREALPHSTTLTSYLPLLGGSRYLEEASIKRIEKSQYFSGLSEGALDNIVQLITLRAGFVEFINALVPDLRVSKTIFHVLSVNWSARVIEQTLLHHTDLTADLLCVHANDFDFDTSTNTTNGRILARNASSLLMNSTDKVREFRRIVQTDAVSSPLNVVYIGDSPTDFGCLQISPISILMRSNQKYYDILSRFEDVQLVDISEFPVQKAVPGKKIIYTCSDWCAIQKAFLA
What are the official names of this protein?
CTO1 family protein C17G9.12c.
What is the protein family that this protein belongs to?
Belongs to the CTO1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: EM4_WHEAT
Sequence: MASGQQERSELDRMAREGETVVPGGTGGKSLEAQEHLADGRSRGGETRKEQLGEEGYREMGRKGGLSTMEESGGERAAREGIEIDESKFKTKS
What is the function of this protein?
It is thought to provide protection for the cytoplasm during the desiccation stage of embryo development.
What are the official names of this protein?
Em protein H5.
What is the protein family that this protein belongs to?
Belongs to the small hydrophilic plant seed protein family.
Protein: PGK_FINM2
Sequence: MNKKTLKDLNVENKRVLVRVDFNVPIKEGIITDTNRIEASLTTIKYLIDNNAKVILMSHLGRPKGEPKPEFSLKPVAQKLSEMIGQDVKFIDSDKVVDDSVIEESKKLQPKEIMLIQNTRFRKEEEKNDQTFSKELSQLADLYVNDAFGTSHRAHASNVGVSKFLPSAVGFLVQKEIEIMGKALENPERPFTAILGGAKVSDKIGVIENLLDKVDTILIGGAMAFTFIKSQGKNVGKSLIEEDKLDLAKSLLEKAQEKGVKIFLPVDFVVAKEMTEESDSKVINIDDFTDDIAGFDIGTKTIKIFDEEIQKSKTIVWNGPMGVFEIEQFSKGTFEIANSLVKSKAITIVGGGDSASAIAKSGNKDKVTHVSTGGGASLEFLEGKVLPGIDCIDER
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MENI_ECOLI
Sequence: MIWKRKITLEALNAMGEGNMVGFLDIRFEHIGDDTLEATMPVDSRTKQPFGLLHGGASVVLAESIGSVAGYLCTEGEQKVVGLEINANHVRSAREGRVRGVCKPLHLGSRHQVWQIEIFDEKGRLCCSSRLTTAIL
What is the function of this protein?
Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA).  Also shows significant activity toward a wide range of acyl-CoA thioesters, and minimal activity toward benzoyl-holoEntB.
What are the official names of this protein?
1,4-dihydroxy-2-naphthoyl-CoA hydrolase, DHNA-CoA hydrolase, DHNA-CoA thioesterase.
What is the protein family that this protein belongs to?
Belongs to the thioesterase PaaI family.
Protein: YAJC_BRUME
Sequence: MFVTPAFAQASGSVVGPDMLMSILPFILIFVIMYFLIIRPQRTQMKKRQEMLNSVRRGDTVVTGGGIVGKVLKVVDDNELELEIADGVRIRVVRATLMDVRVKGEPVADNKNK
What is the function of this protein?
The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes.  While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.
What are the official names of this protein?
Sec translocon accessory complex subunit YajC, Immunogenic membrane protein YajC.
What is the protein family that this protein belongs to?
Belongs to the YajC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PCDB2_PANTR
Sequence: MEAGEGKEPVPKQRQVLIFFVLLGIAQASCQPRHYSVAEETESGSFVANLLKDLGLEIGELAVRGARVVSKGKKMHLQFDRQTGDLLLNEKLDREELCGPTEPCVLPFQVLLENPLQFFQAELRIRDINDHSPVFLDKEILLKIPESITPGTTFLIERAQDLDVGTNSLQNYTISPNFHFHLNLQDSLDGIILPQLVLNRALDREEQPEIRLTLTALDGGSPPRSGTALVRIEVVDINDNVPEFAKLLYEVQIPEDSPVGSQVAIVSARDLDIGTNGEISYAFSQASEDIRKTFRLSAKSGELLLRQKLDFESIQTYTVNIQATDGGGLSGTCVVFVQVMDLNDNPPELTMSTLINQIPENLQDTLIAVFSVSDPDSGDNGRMVCSIQDDLPFFLKPSVENFYTLVISTALDRETRSEYNITITVTDFGTPRLKTEHNITVLVSDVNDNAPAFTQTSYTLFVRENNSPALHIGSVSATDRDSGTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALQSLDYEALQAFEFRVGAADRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSATATLHVLLVDGFSQPYLPLPEAAPAQAQADLLTVYLVVALASVSSLFLFSVLLFVAVRLCRRSRAASVGRCSVPEGPFPGHLVDVSGTGTLSQSYQYEVCLTGGSGTNEFKFLKPIIPNFVAQGAERVSEANPSFRKSFEFS
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.  May be involved in the establishment and maintenance of specific neuronal connections in the brain.
What are the official names of this protein?
Protocadherin beta-2, PCDH-beta-2.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RPOZ_LIGS1
Sequence: MILYPSVDDLLEQVDSRYSLIMLAAKRAHDLDAGSPELLSNYESPKNIGHALEEIAAGKVKIKED
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: YABA_STRA5
Sequence: MDKKDLFDAFDDFSQNLLVGLSEIETMKKQIQKLLEENTVLRIENGKLRERLSVIEAETETAVKNSKQGRELLEGIYNDGFHICNTFYGQRRENDEECAFCIELLYRD
What is the function of this protein?
Involved in initiation control of chromosome replication.
What are the official names of this protein?
Initiation-control protein YabA.
What is the protein family that this protein belongs to?
Belongs to the YabA family.
Protein: WRK65_ARATH
Sequence: MKRGLDMARSYNDHESSQETGPESPNSSTFNGMKALISSHSPKRSRRSVEKRVVNVPMKEMEGSRHKGDTTPPSDSWAWRKYGQKPIKGSPYPRGYYRCSSTKGCPARKQVERSRDDPTMILITYTSEHNHPWPLTSSTRNGPKPKPEPKPEPEPEVEPEAEEEDNKFMVLGRGIETTPSCVDEFAWFTEMETTSSTILESPIFSSEKKTAVSGADDVAVFFPMGEEDESLFADLGELPECSVVFRHRSSVVGSQVEIF
What is the function of this protein?
Transcription factor.  Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity).
What are the official names of this protein?
Probable WRKY transcription factor 65, WRKY DNA-binding protein 65.
What are the subcellular locations of this protein?
Nucleus.
Protein: RAE1L_BOVIN
Sequence: MSLFGTTSGFGSGGTSMFGSTTTDNHNPMKDIEVTSSPDDSIGCLSFSPPTLPGNFLIAGSWANDVRCWEVQDSGQTIPKAQQMHTGPVLDVCWSDDGSKVFTASCDKTAKMWDLNSNQAIQIAQHDAPVKTVHWIKAPNYSCVMTGSWDKTLKFWDTRSSNPMMVLQLPERCYCADVIYPMAVVATAERGLIVYQLENQPSEFRRIESPLKHQHRCVAIFKDKQNKPTGFALGSIEGRVAIHYINPPNPAKDNFTFKCHRSNGTNTSAPQDIYAVNGIAFHPVHGTLATVGSDGRFSFWDKDARTKLKTSEQLDQPISACCFNHNGNIFAYASSYDWSKGHEFYNPQKKNYIFLRNAAEELKPRNKK
What is the function of this protein?
Plays a role in mitotic bipolar spindle formation.  Binds mRNA.  May function in nucleocytoplasmic transport and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton.
What are the official names of this protein?
mRNA export factor, Rae1 protein homolog, mRNA-associated protein mrnp 41.
What is the protein family that this protein belongs to?
Belongs to the WD repeat rae1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle pole. Note=Recruited from interphase nuclei to spindle MTs during mitosis.
Protein: PNP_WOLPM
Sequence: MFKIIKKSIEWGGRALSLETGKIARQAHGSVVVNYGDTSVLVTVVRKKKEESVDFLPLNVQFIAKSYAMGKIPGGFFKREGKPSDRETLISRVIDRSIRPLFPEGFHDEISVVCNLLTYDTVNPPEVPALIGAVAALAISGVPFHFTIAGVMVGCDENNNYILNPSVQEMKASSLDLFLSGDENSILMVESEVKELSEENVFNAIKFGHEHLKPVIKLIKEFADTIGNKPESFAPIDASDITQELEKYGKDFEKAYSQTVKQERVQALEAIRENILNTLKETGKDEKLITYAVKNFERSLVREIIRKKSVRIDGRKHDEIRQIEVEVDILSKTHGSALFTRGNTQALVVTALGTTQDEQIVDDIEGDRREHFMLHYNFPSFAVGETSAARAPGRREIGHGKLAWKAIHPVLPDKSEFPYTIRVVSEILESDGSSSMATVCGTSLALMDTGVPIKAPVAGIAMGLIKDKDEYVILSDILGDEDYLGDMDFKVAGTSEGVTALQMDMKISGISFEIVEKSLEQAKAGRLHILEKMNAVISEHSDDVKDHAPRMLSFYIDKDKISAAIGSKGKNIRSVCERSNAKIEIGDDGKVSVFATSGTEAEIAKSMMIDSITELEQGSIVDVKVVRIEKSIVELEFLNGRKGKMHISEVANEHIDSIESVLKQDDTFKALVIDFEKGGCPKLSRRRVDQETGEFFEGELYNEERKDGPNDRDNYYNNSFSRKPGGSHHKRPPRPHSGFSNRNRPKFGNNDSSSGFY
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTH_XANC8
Sequence: MSALRLIVGLGNPGPEHAQTRHNAGFRFVDALAERTGARWGLDSKLFGETAKADIAGHTVWLLKPATFMNLSGKSITAALRFWKIEPEQLLVAHDELDLAPGTARLKFDGGHGGQNGLRDTIRLLGHGKFHRLRVGIGHPGHKDRVVPWVLGRAGRDDDMAIGEAVDAAIDALPLALDGNFNEAMKRLHTPKK
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VNS2_BTV10
Sequence: MEQKQRRFTKNIFVLDVTAKTLCGAIAKLSSQPYCQIKIGRVVAFKPVKNPEPKGYVLNVPGPGAYRIQDGQDIISLMLTPHGVEATTERWEEWKFEGVSVTPMATRVQYNGVMVDAEIKYCKGMGIVQPYMRNDFDRNEMPDLPGVMRSNYDIRELRQKIKNERESAPRLQVHSVAPREESRWMDDDEAKVDDEAKEIVPGTSGLEKLREARSNVFKEVEAVINWNLDERDEGDRDERGDEEQVKTLSDDDDQGEDASDDEHPKTHITKEYIEKVAKQIKLKDERFMSLSSAMPQASGGFDRMIVTKKLKWQNVPLYCFDESLKRYELQCVGACERVAFVSKDMSLIICRSAFRRL
What is the function of this protein?
Single-stranded RNA-binding protein.
What are the official names of this protein?
Non-structural protein NS2.
What is the protein family that this protein belongs to?
Belongs to the orbivirus non-structural protein NS2 family.
Protein: LGT_NEIMF
Sequence: MIIHPQFDPVLISIGPLAVRWYALSYILGFILFTFLGRRRIAQGLSVFTKESLDDFLTWGILGVILGGRLGYVLFYKFSDYLAHPLDIFKVWEGGMSFHGGFLGVVIAIWLFGRKHGIGFLKLMDTVAPLVPLGLASGRIGNFINGELWGRVTDINAFWAMGFPQARYEDAEAAAHNPLWAEWLQQYGMLPRHPSQLYQFALEGICLFAVVWLFSKKQRPTGQVASLFLGGYGIFRFIAEFARQPDDYLGLLTLGLSMGQWLSVPMIVLGIVGFVRFGMKKQH
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ADHS_METM7
Sequence: MKMFDNIKNVGKLIRLERIFDKKSEKTVIIPMDHGVSSGPLDGLKDMRITTNAVADGGANAVLGHKGLVRHGHRGYGRDIGLIIHMSAGTSLSPDPNKKVIVTTVEDAMRLGADAVSLHVNVGAETDFEMYRDLGLISETCEQWGMPLIAMMYPRGPKIEDEKDPEVVAHAARLGAELGADIIKTNYTGDPDTFKEVVKGCPAPIVIAGGPKTNTDEEFLQMVKDAMHAGGKGVASGRNVFQHKDVKGITSAICKIVHEDVEVKEALKEIKI
What is the function of this protein?
Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH).  Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
What are the official names of this protein?
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase, ADH synthase, ADHS, ADTH synthase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.
Protein: CYB_XENLA
Sequence: MAPNIRKSHPLIKIINNSFIDLPTPSNISSLWNFGSLLGVCLIAQIITGLFLAMHYTADTSMAFSSVAHICRDVNYGWLIRNLHANGASFFFICIYLHIGRGLYYGSFLYKETWNIGVILLFLVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGNVLVQWIWGGFSVDNATLTRFFAFHFLLPFIIAGASILHLLFLHETGSTNPTGLNSDPDKVPFHPYFSYKDLLGFLIMLTALTLLAMFSPNLLGDPDNFTPANPLITPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILALMPLLHTSKQRSLMFRPFTQIMFWALVADTLILTWIGGQPVEDPYTMIGQLASVIYFSIFIIMFPLMGWVENKLLNW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ARGB_THEP3
Sequence: MIRRQKYGDEIAKAQVLIEALPYIKKFSGKTVVIKYGGSAMLDCNLKRMVMQDIVLMKFVGLNPIVVHGGGPEINKMLERLGIESKFVNGLRVTDEATMEIVEMVLTGRINKEIVSLINELGGQAIGVSGKDGRLLKAEKDTSNGDIGYVGKIVDVNIDVITMMLEKGYIPVIAPTSFGDDGKTYNVNADTAAGKIAEALKAEKLILLTDVEGILSNINDKSSLISRMDLEHAKEFMNSGRINGGMIPKLECCIKAVENGVKRAHIIDGRLTHSLLLEIFTDEGIGTMIGKECFDDDNL
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FDHL_STAA8
Sequence: MQEHLVVTLDGKDYLVEPGTNLLEFIKSQDTFVPSICYNESMGPIQTCDTCTVEIDGKIERSCSTVIDRPMTVNTVNNDVKDAQKEALDRILEKHMLYCTVCDYNNGDCEIHNTMDAWGLQHQTYEYKEKPYEKDYGPFYRYDPNQCILCGRCVEACQDIEVNETIRIDWDREHPRVIWDNDVPINESSCVSCGQCATVCPCNAMMEVNMEGNAGYMTDTEPGSLAAMIDLTKKAEPGYGPLFAISDSEAEMRKERIKKTKTVCTYCGVGCSFEVWTKDREILKVQPSHDSPANKIATCVKGKFSWGHINSDQRLTKPLVRKNGEFHEVEWDEALNVIADNFTAIKEKHGPDALSFISSSKATNEESYLMQKLARQVIGTNNVDNCSRYCQAPATKGLFRTVGHGGDSGSIEDLEKAAMSVLIGTNTAEAHPVIASRMKRAQKLFGQKIHVFDIRKHEMAERADRFYQPKPGTDLAWLSAVTKYIIDHDLHDKAFIDEWVDDFDEYYKSLETFTMAFAEEATGIPESELIKFAEECAKAESVVICWAMGITQQDIGSDSSTAISNLLLVTGNYRRPGTGAYPLRGHNNVQGCSDMGSMPDKITGYQSIEADDIRAKFEKEYGVKLNPKAGKDNHEMVEGIHDGEVHSLYLYGEDTGIVDSNINFVQAAFEKLDFMVVQDEFLTFTATYADVVLPASPSLEKDGTFTNTERRIQRLYQALEPLGDSKPDWKIFQAIANRLGFDWNYKHPSEIMDEVARLTPLYAGVSYDRLEGFNSLQWPVQPDGTDEPILYLEGFNFDNGKAKLFPLSFDNYFKQDEIYDIHVNNGRLLEHFHEGNMTYQTPMIKYKVPRAFVEISPELAEDRGIHEGAEVKLISETGEAVLQVHVTDRVKGKEIYIPLNNDAMENGDLGAINLLTNSDVDQYTDTPSYKRTSCRLEVITKRGKSPLNPNNFRVNKKRQPQYSVQVQKKWERSDYVFPGNQVDK
What are the official names of this protein?
Putative formate dehydrogenase SAOUHSC_02582.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
Protein: FGF18_MOUSE
Sequence: MYSAPSACTCLCLHFLLLCFQVQVLAAEENVDFRIHVENQTRARDDVSRKQLRLYQLYSRTSGKHIQVLGRRISARGEDGDKYAQLLVETDTFGSQVRIKGKETEFYLCMNRKGKLVGKPDGTSKECVFIEKVLENNYTALMSAKYSGWYVGFTKKGRPRKGPKTRENQQDVHFMKRYPKGQAELQKPFKYTTVTKRSRRIRPTHPG
What is the function of this protein?
Plays an important role in the regulation of cell proliferation, cell differentiation and cell migration.  Required for normal ossification and bone development.  Stimulates hepatic and intestinal proliferation (By similarity).
What are the official names of this protein?
Fibroblast growth factor 18, FGF-18, zFGF5.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Secreted.
Protein: MUKF_ECO57
Sequence: MSEFSQTVPELVAWARKNDFSISLPVDRLSFLLAVATLNGERLDGEMSEGELVDAFRHVSDAFEQTSETIGVRANNAINDMVRQRLLNRFTSEQAEGNAIYRLTPLGIGITDYYIRQREFSTLRLSMQLSIVAGELKRAADAAEEGGDEFHWHRNVYAPLKYSVAEIFDSIDLTQRLMDEQQQQVKDDIAQLLNKDWRAAISSCELLLSETSGTLRELQDTLEAAGDKLQANLLRIQDATMTHDDLHFVDRLVFDLQSKLDRIISWGQQSIDLWIGYDRHVHKFIRTAIDMDKNRVFAQRLRQSVQTYFDEPWALSYANADRLLDMRDEEMALRDEEVTGELPPDLEYEEFNEIREQLAAIIEEQLAVYKTRQVPLDLGLVVREYLSQYPRARHFDVARIVIDQAVRLGVAQADFTGLPAKWQPINDYGAKVQAHVIDKY
What is the function of this protein?
Involved in chromosome condensation, segregation and cell cycle progression.  May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.  Not required for mini-F plasmid partitioning.  Probably acts via its interaction with MukB and MukE.  Overexpression results in anucleate cells.  It has a calcium binding activity.
What are the official names of this protein?
Chromosome partition protein MukF.
What is the protein family that this protein belongs to?
Belongs to the MukF family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.