PharMolix/UniProtQA huggingface dataset:
Protein: KDSA_ECOL6
Sequence: MKQKVVSIGDINVANDLPFVLFGGMNVLESRDLAMRICEHYVTVTQKLGIPYVFKASFDKANRSSIHSYRGPGLEEGMKIFQELKQTFGVKIITDVHEPSQAQPVADVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQFVSPGQMGNIVDKFKEGGNEKVILCDRGANFGYDNLVVDMLGFSIMKKVSGNSPVIFDVTHALQCRDPFGAASGGRRAQVTELARAGMAVGLAGLFIEAHPDPEHAKCDGPSALPLAKLEPFLKQMKAIDDLVKGFEELDTSK
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGD_STRMU
Sequence: MSNLFQNYTRADLEFIKAEGNYLFDTQGKKYLDFSTGIGVTNLGFHPQVQVALQKQAEQIWHTPNLYQNSLQEEVAAKLMAGKDYLAFFCNSGAEANEAAIKIARKATGKQEIITFQNSFHGRTFGSMSATGQDKIKVGFGDAVPHFHYAVFNDLNSVKALVTENTAAVMLELVQGESGVLPAEQDFVTALADYCQKNGLLLIIDEVQTGMGRTGKLYAFQHYGIEPDIFTLAKGLANGVPVGAMLAKKQFGSAFGPGSHGSTFGGNKLAMAASSAVLDIMTKAGFLEQAWENAHYLQEQLTSALQVADTVTQVRGLGYMIGIETTADLGQLVKATRDRGLIVLTAGTNVIRLLPPLTLTKDEIDQGIMILQEVFEQHN
What are the official names of this protein?
Acetylornithine aminotransferase, ACOAT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSD_CROS8
Sequence: MLNEIKLSLQYILPKQWLTRLAGWGASKRAGWLTKLVIDLFVKYYKVNMSEAQKPDTASYRTFNEFFVRPLRDEVRPLNTDPNVLAMPADGVISQLGRIEGDKILQAKGHNYSLEALLAGNYLMADLFRNGTFATTYLSPRDYHRVHMPCNGILREMIYVPGDLFSVNHLTAQNVPNLFARNERVICLFDTEFGPMAQILVGATIVGSIETVWAGTITPPREGIIKRWTYPAGESDGAVALLKGQEMGRFKLGSTVINLFAPGKVELVEHLQSLSVTRLGEPLAVSVEAVAADVAPAVISQEEADAEREANPLVDNDQNR
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: AIMP1_MOUSE
Sequence: MATNDAVLKRLEQKGAEADQIIEYLKQQVALLKEKAILQATMREEKKLRVENAKLKKEIEELKQELILAEIHNGVEQVRVRLSTPLQTNCTASESVVQSPSVATTASPATKEQIKAGEEKKVKEKTEKKGEKKEKQQSAAASTDSKPIDASRLDLRIGCIVTAKKHPDADSLYVEEVDVGEAAPRTVVSGLVNHVPLEQMQNRMVVLLCNLKPAKMRGVLSQAMVMCASSPEKVEILAPPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQPDLHTNAECVATYKGAPFEVKGKGVCRAQTMANSGIK
What is the function of this protein?
Non-catalytic component of the multisynthase complex (PubMed:12060739).  Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase (By similarity).  Binds tRNA.  Possesses inflammatory cytokine activity (PubMed:1400342, PubMed:7545917).  Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation (PubMed:18448069).  Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels (PubMed:17001013).  Promotes dermal fibroblast proliferation and wound repair (PubMed:15681823).  Regulates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticulum (PubMed:17525271).  Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations (By similarity).  Induces maturation of dendritic cells and monocyte cell adhesion (PubMed:18292511).  Modulates endothelial cell responses by degrading HIF-1A through interaction with PSMA7 (By similarity).
What are the official names of this protein?
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1, Multisynthase complex auxiliary component p43.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol. Secreted. Endoplasmic reticulum. Golgi apparatus. Note=Enriched in secretory vesicles of pancreatic alpha cells and secreted from the pancreas in response to low glucose levels (PubMed:17001013). Secreted in response to hypoxia (By similarity). Also secreted in response to both apoptotic and necrotic cell death.
Protein: ICSP_SHIFL
Sequence: MKLKFFVLALCVPAIFTTHATTNYPLFIPDNISTDISLGSLSGKTKERVYHPKEGGRKISQLDWKYSNATIVRGGIDWKLIPKVSFGVSGWTTLGNQKASMVDKDWNNSNTPQVWTDQSWHPNTHLRDANEFELNLKGWLLNNLDYRLGLIAGYQESRYSFNAMGGSYIYSENGGSRNKKGAHPSGERTIGYKQLFKIPYIGLTANYRHENFEFGAELKYSGWVLSSDTDKHYQTETIFKDEIKNQNYCSVAANIGYYVTPSAKFYIEGSRNYISNKKGDTSLYEQSTNISGTIKNSASIEYIGFLTSAGIKYIF
What is the function of this protein?
Protease responsible for the cleavage of IcsA between 'Arg-758' and 'Arg-759', removing the entire alpha domain from IscA localized on the bacterial surface.  This proteolytic activity contributes to the maintenance of a tight polar cap of IcsA, which is important to Shigella actin-based motility.
What are the official names of this protein?
Outer membrane protease IcsP.
What is the protein family that this protein belongs to?
Belongs to the peptidase A26 family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: Y6530_RHOBA
Sequence: MNEENAAENESSQPKPLSATARRCLGVLVEKAKTTPDGYPLSLAGLITGCNQKSNRSPQMQVDESDALLALDELRAAGAAREIQGSGRVTKYRHAAYEWLGVDSPGAAIVTELMLRGPQTAGELRTRASRMHKFPDLDSLKTELDSLIEKGLVESLTPPGRGQTFAHCLYTPQERLYLVDKIKKQDASSAAPSQAESGSTSPAKAANDDRIDKIQERLDSVTAKLEALEKRLEFLES
What are the official names of this protein?
UPF0502 protein RB6530.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: RL27_METRJ
Sequence: MAHKKAGGSSRNGRDSEGRRLGVKKFGSEAVIPGNIIVRQRGTKWHPGANVGMGKDHTIFALVPGHVRFETRRGRAFVGVTPLAEAAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: ATPA_SYNWW
Sequence: MSIRPEEISAILKEQIERYQSEVEVSNVGSVIYVGDGIARVYGLQGAMAGELLEFTGGTFGMVLNLEEDNVGAVLLGEYNHIKEGDVVKATGRIMEVPAGSAMLGRVVNALGQPIDGKGPINTTAFRPLEKVAHGVVTRQPVTTPMQTGLKAIDSMVPIGRGQRELIIGDRQIGKTAIALDSIINQREKKDLICIYVAVGQKQASIAGIAAKFEEMGAMDYTIIVAATASEPAPLLYMAPYAGVAMAEEFMEAEGKDVLIIYDDLSKHAVAYREMSLLLRRPPGREAYPGDVFYLHSRLLERACRLNPDHGGGSITALPIIETQAGDVSAYIPTNVISITDGQIYLEADMFNAGQRPAVNAGLSVSRVGGSAQTKAMKSVAGQLRLDLAQYRELAAFAQFGSDLDKATLARLTRGERVTEILKQGQYQPMPVQEQVVSIYSGVNGYLDDIPRDKVGEFEVDFLKFMRSANADVLNAIKDTGKIDDATEQKLIKAINEFKSTFAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: EMPA_VIBAN
Sequence: MKKVQRQMKWLFLAASISAALPVSAAKMVQVDDPSLLEQALSMQARSIVPTQNGFQVVKSVTLPNGKVKVRYQQMYHGLPVFNTSVVATQTEKGIGQVYGMLAQQIDSDVVSTSPQVEQKQAVSIALTHYQQQNPSLTSADLVTENERAQLMVRLDENQMAQMVYLVDFFVATNEPARPFFFIDANSGDVLQTWEGLNHAEATGTGPGGNQKTGFYQYGTDFPGLVINKVGNTCSMMNSAVKTVDMKHATSGGSTFSYSCTDASNYNDYKAINGAYSPLNDAHYFGKVVFDMYKDWMNTTPLTFQLTMRVHYDSNYENAFWNGSSMTFGDGQNTFYPLVDINVSAHEVSHGFTEQNSGLVYQNMSGGINEAFSDIAGEAAEFYMKGSVDWVVGSDIFKSSGGLRYFDQPSKDGRSIDHASQYYNGLNVHYSSGVFNRAYYLLANKANWSVRKGFEVFTVANQLYWTANSTFDQGGCGVAKAAQDLGYNKADVVDAFNQVGVNASCGVVPPTENVLEKGKPVIGLQGTRSSEAFYTFTVASSTSAKVSISLGSGDADLYVKAGSKPTTSSWDCRPYKSGNNEQCTISATPGTTYHVMLKGYSNYSGVTLRLD
What is the function of this protein?
Extracellular zinc metalloprotease involved in the virulence mechanism of V. anguillarum.
What are the official names of this protein?
Virulence metalloprotease, Vibriolysin.
What is the protein family that this protein belongs to?
Belongs to the peptidase M4 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS9_STAA9
Sequence: MAQVEYRGTGRRKNSVARVRLVPGEGNITVNNRDVREYLPFESLILDLNQPFDVTETKGNYDVLVNVHGGGFTGQAQAIRHGIARALLEADPEYRGSLKRAGLLTRDPRMKERKKPGLKAARRSPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: HSLV_SULSY
Sequence: MEKIKSTTILAVRRNGKTVIAGDGQVTLGSAVVKHTAKKIRVLNEGKVIVGFAGSAADGLALMERLEEKLNKYKGNLVKSAVELAKDWRLDKYLRRLEAVMIAADKNNMLLLSGNGDVIEPDEPVLAIGSGGDYARSAALALYRNTDLDARKIVEEAMKIAGEICIYTNQNFVIEEIE
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUB_THEON
Sequence: MARDEVRRILPADIKREVLIKDEKAETNPKWGFPPEKRPMEMHMQFGIINLDKPPGPTSHEVVAWVKKLFNLNKAGHGGTLDPKVSGVLPVALERATRVVQALLPAGKEYVALMHLHGEVPEDKIYAVMKEFEGEIIQRPPLRSAVKRRLRTRKVYYIEILEIDGKDVLFRVGVEAGTYIRSLIHHIGLALGVGAHMAELRRTRSGPFKEDETLVTLHDLVDYYHFWKEDGIEEYFRKAIQPMEKAVEHLPKVWIRDSAVAAVTHGADLAVPGIVKVHKGIKKGDLVAVMTLKDELVALGKATMTSGEMLQKSKGIAVDVDKVFMPRDWYPKLW
What is the function of this protein?
Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
Probable tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
Protein: RPOB_LACSA
Sequence: MSTIPGFNQIQFEGFCRFIDQGLTEELSKFPKIEDTNQEIDFELFLERYQLVEPSIKERDAVYESLTYSSELYVSARLIWKNDRRRYIQEQTILIGKIPLMTSLGAFIVNGIYRIVINQILQSPGIYYQSELNDNGISVYTGTIISDWGGRLELEIDRKTRIWVRVSRQQKLSILVLLSAMGLNIREILENVCYPELFLSFLNDKKQIGSKENAILEFYQQFACVEGDPVFSESLSKDLQKKFFQQRCELGGIGRRNMNRRLNLDIPQNNTFLLPRDILAAADRLIRIKFGMGTLDDMNHLQNKRIRSVADLLQEQFGLALVRLENMARGNIYAALKHNWTPTPQNLVNSTPLTDTYKVFFRLHPLSQVLDRTNPLTQIVHGRKLSYLGPGGLTARTATFPIRDIHPSHYGRICPIDTSEGINVGLIGSLAIHARIGRWGSLESPFYKISERSKGARMLYLSPGRDEYYMVAAGNSLALNQGIQEEQVVPARYRQEFLTIAWEQVHLRSIFSFQYFSIGASLIPFIEHNDANRALMSSNMQRQAVPLSQSEKCIVGTGLEGQAALDSGALAIAEHEGEIIYTDTDKILLSGNGDTLRIPLVMYQRSNKNTCMHQKPQVQRGKCIKKGQILAYGAATVGGELALGKNVLVAYMPWEGYNFEDAVLISERLVYEDIYTSFHIRKYEIQINQGSERVTNEIPHLEVHLLRNLDKNGIVMLGSWVETGDILVGKLTPQMVKESSYAPEDRLLRTILGMRVYTSKETCLKLPIGGRGRVIDVRWVQSSKTDETEKTESIRVYILQKREIKVGDKVAGRHGNKGIISKILPRQDMPYLQDGRPVDMVFNPLGVPSRMNVGQIFESSLGLAGGLLDRHYRIAPFDERYEQEASRKLVFSELYEASKQTVNPWIFEPESPGKSRIFDGRTGDPFEQPVIIGKPYILKLIHQVDDKIHGRSSGRYSRLTQQPLKGRAKKGGQRVGEMEVWALEGFGVAYILQEMLTYKSDHIRARQEVLGTIIFGGRIPTPEDAPESFRLFVRELRSLALELNHFLVSEKTFQLNRKEA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, PEP, Plastid-encoded RNA polymerase subunit beta, RNA polymerase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DCUP_RICBR
Sequence: MTLISSPIKRLDNKPPIWLMRQAGRYLSEYMAVRKEVKNFLEFCYDVDKATEVTLQPIKRFGFDAAIIFSDILVLPHALGWEVDFKENIGPLLKQFKSKEDFKYLQDNSNDKLEKVYEIVKKVRKELPKSTSLIGFAGSPWTVMTYMLEGKGKQDFRVSKKFIYENKDLAKELLNFITEKTIHHLINQIKSGANIIKIFDSWAGILPEEEFKKFVIEPTKKIIKSIKGYFPDIPIITFPKGAGLLYEKFLEEVPTDIIAIDPLIPLEKMKLWSNKVTVQGNLDPVILLTNKKIIKEKIHKILSIMENKNFIFNLGHGILPETPPENVEFLVKCIREYEYK
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHON_SALTI
Sequence: MKSRYLLFFLPLIVAKYTSAATMQPFHSPEESVNSQFYLPPPPGNDDPAFRYDKEAYFKGYAIKGSPRWKQAAEDADISVENIARIFSPVVGAKINPKDTPETWNMLQNLLKMGGYYATASAKKYYMRTRPFVLFNHSTCRPEDENTLRKDGSYPSGHTAYSTLLALVLSQARPERAQELARRGWEFGQSRVICGAHWQSDVDAGRYVGAVEFARLQTIPAFQKSLAKVREELNDKNNLLSKEERPELNY
What are the official names of this protein?
Non-specific acid phosphatase, NSAP.
What is the protein family that this protein belongs to?
Belongs to the class A bacterial acid phosphatase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: KMO_XANC5
Sequence: MSPVSPRSLTLIGAGLAGCLLAILLSRRGWQVTVYERRGDPRIKGYESGRSINLALAERGRHALRQAGAEDAVMAKAVMMRGRMVHPIIGQPQLQRYGRDDSEVIWSIHRAALNVALLDLAEQAGARVHFYRRLHTVGFDAGYARFIDDRDDQPHEIHFQSLIGSDGAGSALRAAMQRKSPLGERTEFLDHSYKELEIPPQPGGGFRIEGNALHLWPRGRYMCIALPNDGGTFTVTLFLPNAGEPSFATTRTGDEALALFARDFPDALPLIPQLREHWEEHPPGLLGTLTLDRWHLDGRALLIGDAAHAMVPFHGQGMNCAFEDCVALADQLDAHDDLASAFAAFEAARRDDAAAIQQMALENYLEMRDRVDDPDFLLQRELEQKLQARWPTRFVPHYTMVTFLRTRYSIALARSEIQRQILVEATRGHRDLSRIDWAALEAVVHARLEPLDGAH
What is the function of this protein?
Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn).  Required for synthesis of quinolinic acid.
What are the official names of this protein?
Kynurenine 3-monooxygenase, Kynurenine 3-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
Protein: DBNL_DICDI
Sequence: MASLDISDPDITKYIKLVQDGNPANRWIVFSYVPKSNNKIKFCDSGSGDLKELREELDDSSIRFAYIRFVINNMPKFVYIPWCGDGVNGPIKGAFSGHAIEFSKSFKPIHHQVNARSEEDIDEKAITAALNKATGASYDSGSKVQGATKGTFIPQSVSQGREAATKSNAEVKNVINKNDYNKIQESAEYWKQNQANKSEPAKPTRPEYNLSTERDDYWKQQQAEKQKQQQQQQQQQASRVNAPPPSRTVGNKFQEQVSKPTETAPPQPRPAPSKGSVLNRFPAATQQQQEPPAPSRPAAPVPSRVNKPAAPVQPVYQEPVHEEPQYEEPQYEEEQQQQYEEQPTEEQQYYQEEPQQQYEEQPTEEQQYYQEEQQQYEEQPTEEQQYYQEEQQQYEQPTEDQQYYQEEQQQYEQPAEEQYDQSGYLQAKALYDYNGENDGDLSFREGDIITILDQSDPDGWWQGSLPTGEQGFFPSNFVQQL
What is the function of this protein?
Actin-binding adapter protein.  Binds to F-actin but is not involved in actin polymerization, capping or bundling.  Does not bind G-actin.  Controls pseudopodium number and motility in early stages of chemotactic aggregation.
What are the official names of this protein?
Drebrin-like protein, Actin-binding protein 1, Dabp1, Actin-binding protein E.
What is the protein family that this protein belongs to?
Belongs to the ABP1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, pseudopodium.
Protein: PHT3_ORYSJ
Sequence: MEVKVLSSKLVKPAYNGGVAAAPDVEYIPLSIFDKVTYKMQMAIIYAFPPPAPSTAAIEKGLAAVLAQYRAFAGQLGESPDGEAAVVLNDRGARLVEAAVDADLVDMAPAKPTPELLRLHPDLEGELQEVVLLQLTRFRCGSLAVGFTSNHVVADGHATSNFLVAWGRATRGLPMGAPPVHHHAALFKPRPSPHVEHDHRNREYYLPAAGDDSHGHGDGGAADNIVIHKAHFTKDFIAGLRAAASEGRGRPFSRFETILAHLWRTMTRARGLSPDEASTIRLSVDGRHRLGAPAEYFGNLVLWAFPRATVGDLLTRPLKHAAQVIHDEVARVDGAYFRSFLDFALSGAGGDKEGLAPSAVLKDVLCPNAEVDSWLTFPFYELDFGTGSPTYFMPSYFPTEGMLFLVPSYLGDGSVDAFVPVFNHNLEAFKECCYSME
What is the function of this protein?
Hydroxycinnamoyl transferase that catalyzes the transfer of an acyl from p-coumaryol-CoA to putrescine, to produce coumaroyl putrescine.  Can use feruloyl-CoA and caffeoyl-CoA as acyl donors.
What are the official names of this protein?
Putrescine hydroxycinnamoyltransferase 3, OsPHT3.
What is the protein family that this protein belongs to?
Belongs to the plant acyltransferase family.
Protein: THIG_BARBK
Sequence: MLNFYGHEFSSRLLLGTAQYPSPEILRKVIDKSGTEIVTVSLRRETAGGKHSGQFWQFLKELNVTILPNTAGCYTIKEAVTTAQLARDLFKTPWIKLEVIGNPDTLQPNIFALVEAAQILNNEGFQIFAYTTDDLIVAEKLLEVGCRVIMPWCAPIGSAKGPRDTDGLRSIRAYLPDLTLVIDAGIGRPSHATIAMELGYDAILLNTAVAKSGDPVLMAEAFSKAVNAGYMAYKAGILEARDVAVPSTPIIGKAVFS
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYSY_LATSS
Sequence: MSEQVYLDLARTILEEGHYKGDRTNTGTYSLFGYQMRFNLQEGFPLLTTKKMPFGLIKSELLWFLKGDSNIRYLLQHNNHIWDEWAFERFVKSTDYTGPDMTDFSHRAQDDADFKVVYQEQMRLFNDRILADEGFAKQYGELGDIYGKQWRAWQTRSGETIDQIKNVIEMIKTNPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVNDGKLSCQLYQRSGDVFLGVPFNIASYALLTHLIAHETGLEVGEFIHTLGDAHIYSNHVTQVKTQLARSMHAAPKLWLNPDKKSIFDFDVADIKVENYESEPAIKAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RADA_RICPR
Sequence: MTRDKKYYICSNCANISNKWSGQCFDCGVWGSIVEEIINTNKSIIKGSKQTFDKLSCNVSEQLRIPTPICELNRVLGGGLVLGSAILIGGEPGIGKSTLLLQLTASNFESEMRCLYITGEESLDQIKLRAIRLNITNYNTAILAATNLEDIIASIDDNNNNIDLVVIDSIQTITTKELSSPPGTVSQIRTCANELVNYSKQNNIIILLSCHVTKDGQIAGPKILEHLVDTVLYFEGDHNNHFRILRSYKNRFGGVGEIGVFEMSNSGIIEVTNHSELFLIKREHNVVGTSIFAGIEGSRPLLMEVQALIVPSNMVTPRRSAVGWDANRLSMILAVLSSRIGLNLANYEIYLSIAGGLKIADPASDLAVAASLISAATSIPLPEHSVFFGEISLSGEIRKTAKAETRIKEAVKLGFNKVICSKLENLTYDFIFPCAHLQELKEIIK
What is the function of this protein?
DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks.  Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster.  Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB.  Does not have RecA's homology-searching function.
What are the official names of this protein?
DNA repair protein RadA, Branch migration protein RadA.
What is the protein family that this protein belongs to?
Belongs to the RecA family. RadA subfamily.
Protein: UDA1_CAEEL
Sequence: MLFPAFSILLISFFSLLSVVTTKTQYWCHGDGVLNNQHTCRFFTIVIDAGSTGTRLHLYKFIHDPAIASHGMPFKVEKEIFQEVKPGLSSFAKSPSSAADSLEPLLQRARKEVPHFMWEKTPITLKATAGLRLLPGDMADDILESVEERIFNSGFFAAFPDAVNVMPGSDEGVYSWFTLNILLETLFTDEPTVGHKPAAHRSVAAFDLGGGSTQLTYWPNNEAVFSEHVGYERDIDFFGHHIRLFTHSFLGNGLIAARLNILQLETDNEIESTHQLITSCMPEGYQLTEWEYALKFWNINGSSSHSFESCYGTTKNFVESSEIMHLRELKGSPVYLFSYFFDRALNSGLVKGNEGGKIELRQFKEAAEIACRREKTEIDDGSHWMPWQCLDLTYIYSLLRDGYQFEDNQPLVLAKKIKGMEVSWGQGLAFATANEFQLTEGAIKTALSSEPNSTVVDQIFDLVYSGTNQVLSYFNIISV
What is the function of this protein?
Hydrolyzes UDP and GDP but not any other nucleoside di-, mono- or triphosphates.  May promote reglycosylation reactions involved in glycoproteins folding and quality control in the endoplasmic reticulum.
What are the official names of this protein?
Nucleoside-diphosphatase uda-1, Uridine-diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the GDA1/CD39 NTPase family.
What are the subcellular locations of this protein?
Endomembrane system; Single-pass type II membrane protein.
Protein: UREG_PSEP1
Sequence: MQSYQQPLRVGVGGPVGSGKTALLEALCKAMRDHYQIAVVTNDIYTKEDQRILTEAGALEPERIVGVETGGCPHTAIREDASMNLAAVEALARKFGNLEVIFVESGGDNLSATFSPELADLTIYVIDVAEGEKIPRKGGPGITKSDFLVINKTDLAPYVGASLEVMERDTQRMRPQRPWTFSNLKKGEGLQAVIDFIVERGMLGARA
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IXTPA_RALSO
Sequence: MRRIVLASNNPGKLAEFNALLAPLGLDVAPQGELGIPEAEEPHATFVENALAKARHASRLAGLPALADDSGICAHALGGAPGVYSARYAQLAGGPKSDAANNARLVRELAGHADRGAHYVCVLVYVRHADDPQPIIAEGSWFGEVIDAPRGDGGFGYDPHFLLPALGKTAAELSKAEKNAVSHRAQALAQLVERLRLFENA
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: TRUA_PYRIL
Sequence: MPYLYRIAYDGTLFYGFTGHSRSLEPALKRVFGEILGRGSRTDPGVSAVANTVMVSQKLPIALVNSKLPRGVWAWAIAEVPQSFNPRRAKFRHYLYVAPHWGEDLGSMHEAAEVLAGTHDFASFIQRRGEKISTIATVMEIKVELRGDLIYMHFVGRGFKNKMIRKLAWAILAAGRGIFNIRDIRELLERPRPGVVPSAPAEGLVLLNIEYDVDFQIDYTALRSAYVYFLSKYRHAVAHAAALKAVGETLATWEQ
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: FABF_ECOL6
Sequence: MSKRRVVVTGLGMLSPVGNTVESTWKALLAGQSGISLIDHFDTSAYATKFAGLVKDFNCEDIISRKEQRKMDAFIQYGIVAGVQAMQDSGLEITEENATRIGAAIGSGIGGLGLIEENHTSLMNGGPRKISPFFVPSTIVNMVAGHLTIMYGLRGPSISIATACTSGVHNIGHAARIIAYGDADVMVAGGAEKASTPLGVGGFGAARALSTRNDNPQAASRPWDKERDGFVLGDGAGMLVLEEYEHAKKRGAKIYAELVGFGMSSDAYHMTSPPENGAGAALAMANALRDAGIEASQIGYVNAHGTSTPAGDKAEAQAVKTIFGEAASRVLVSSTKSMTGHLLGAAGAVESIYSILALRDQAVPPTINLDNPDEGCDLDFVPHEARQVSGMEYTLCNSFGFGGTNGSLIFKKI
What is the function of this protein?
Involved in the type II fatty acid elongation cycle.  Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor.  Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.
What are the official names of this protein?
3-oxoacyl-[acyl-carrier-protein] synthase 2, 3-oxoacyl-[acyl-carrier-protein] synthase II, Beta-ketoacyl-ACP synthase II, KAS II.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
Protein: OSTCN_LAMGU
Sequence: YLDHGLGAPAPYVDPLEPKREVCELNPDCDELADQMGFQEAYRRFYGTT
What is the function of this protein?
Constitutes 1-2% of the total bone protein.  It binds strongly to apatite and calcium (By similarity).
What are the official names of this protein?
Osteocalcin, Bone Gla protein, BGP, Gamma-carboxyglutamic acid-containing protein.
What is the protein family that this protein belongs to?
Belongs to the osteocalcin/matrix Gla protein family.
What are the subcellular locations of this protein?
Secreted.