PharMolix/UniProtQA huggingface dataset:
Protein: GLPK_TREDE
Sequence: MKKYVLAFDQGTTSCRAILFDKDGKKIETAQQEFSQIFPKQGWVEHDAMEIWGKQSGVAREVLERSGVSTQEIAAIGITNQRETTVVWNKNTGRPVCNAIVWQCRRTADICDALKEKGLSDSIRKKTGLIIDAYFSGTKIKWILDNVPEARTLAEKGELLFGNIDTWLIWNLTRGKVHVTDYTNASRTLLFNIHTLQWDKELLKAMDIPESMLPEVKPSSYVYGYTEEHTFGGSKIPIAGAAGDQQAALFGQACFEEGSAKNTYGTGCFMLMNTGDKIIESENGLLTTIAFGIDNSVKYALEGSSFIAGAAVQWLRDELKLIYTAHETEYYAGLVNDTNGVYFVPAFSGLGAPYWDMYARGALLGLTRGAKREHIVRAVLEAIAYQTKDVLYAMEKDSKINLKSLKVDGGACANNFLMQFQSDILNVPVLRPYEKETTALGAAYLAGLAVGFWKEQGEIKRIQDIEREFRPDMEEEKRKTLYAGWKKAVERSMKWA
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: UFAP2_PIG
Sequence: MSHGKMPLVLSLVLILCGLFNSISCEKQQTSPKTITPVSFKRIAALSQKMEANYKAFAQELFKTLLIEDPRKNMIFSPVSISISLATLSLGLRSATRTNAIDVLERDLRNLRVWDKHQALQHLVEMLHELEKKKQLKHKDIFFIDRNKKMNQMFLKEIDRVYKVDIQMIDFKDKEKTKKAINQFVADKIDKKAKNLITHLDPQTLLCLVNYVFFKGILERAFQTNLTKKEDFFVNEKTIVQVDMMRKTERMIYSRSEELLATMVKMPCKENASIILVLPDTGKFDFALKEMAAKRARLQKTNELQIGALSCAQDQDHLQDRFKHLLPKIGINDIFTTKAVTWNTTRTSTILEAVHHAVIEVKEDGLTKNAAKDKDFWKVPVDKKEVPVVVKFDRPFFLFVEDEITRRDLFVAKVFNPKTE
What are the official names of this protein?
Uteroferrin-associated basic protein 2, UABP-2.
What is the protein family that this protein belongs to?
Belongs to the serpin family. UTMP subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: YAJC_CHLTR
Sequence: MYSRLFFSILFFLGCCPALFADTDSPQRATFGQPAVMLGIAIVFFYFILWRPEQKRRQAMEKRKSELAVGDKVTAMGIVGTIAEIREHTVILNIASGKIEILKAAISEILKAEK
What is the function of this protein?
The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes.  While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.
What are the official names of this protein?
Sec translocon accessory complex subunit YajC.
What is the protein family that this protein belongs to?
Belongs to the YajC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RUVB_CLAM3
Sequence: MSGLEHGDASSPVPESDAELAFEGALRPRSLSEFVGQVKVRGQLELLLTAAAMQNRSPDHILLAGPPGLGKTTLAMIVAEESRRPLRLTSGPAIQHAGDLAAVLSALVPGEILFVDEIHRMARSAEEMLYLAMEDYRIDIMVGKGAGATSIPLELSPFTLVGATTRSGMLPSPLRDRFGFTAHLEFYETHELEQVIERAARMLHLEIEHEAVAEIAGRCRGTPRIANRLLRRVRDYALVHGTEAGLESVRAALDLYDVDPLGLDRLDRAVMRGILTRFGGGPVGLNTLAVSVGEEAETIESVVEPFLVRIGLVTRTPRGRVATPAAWEHFGLEAPAAPGAPARASGPASVAGALFGDEL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: ARM10_HUMAN
Sequence: MGGPRGAGWVAAGLLLGAGACYCIYRLTRGRRRGDRELGIRSSKSAGALEEGTSEGQLCGRSARPQTGGTWESQWSKTSQPEDLTDGSYDDVLNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQSIKEKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVQLAGLTLLTNMTVTNDHQHMLHSYITDLFQVLLTGNGNTKVQVLKLLLNLSENPAMTEGLLRAQVDSSFLSLYDSHVAKEILLRVLTLFQNIKNCLKIEGHLAVQPTFTEGSLFFLLHGEECAQKIRALVDHHDAEVKEKVVTIIPKI
What is the function of this protein?
May play a role in cell survival and cell growth.  May suppress the transcriptional activity of p53/TP53.
What are the official names of this protein?
Armadillo repeat-containing protein 10, Splicing variant involved in hepatocarcinogenesis protein.
Protein: IHFA_ECO27
Sequence: MALTKAEMSEYLFDKLGLSKRDAKELVELFFEEIRRALENGEQVKLSGFGNFDLRDKNQRPGRNPKTGEDIPITARRVVTFRPGQKLKSRVENASPKDE
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: RFCL_METLZ
Sequence: MDWAEKYRPMHLADILGNGSAVRQIVDWAKTWTPDSRPLLFTGKPGIGKTSAALALARDMDWEVLELNASDARTKTIIERVAGNSSTTTSLFGAGRKLIIIDEVDNLEGNADRGGARAIADILKEAKQPIVLIANDAYGVSDSIRRLCDPVPFRAIGVSTLQKRMKEICRFEDIACGEDALSAIAESSAGDMRTAVNMLFGSSTGKTSISVGDINTAQKDERATIFDLVGGVFAGAPDRELQKLSFECDEKPDSVMQWIEESIPLMHDPKRRIRAYGRISRADVYLGRTMRRQYFTLWRYATSMMTLGVASENAGAGFRTRIMPPSRWKRMSTAKKQKTVRRTLAASLAEGYSIPERQIQSEYLDLLSRFAEKDPAAFCERHNLDVDQMGIILHDKAAAAAAVKTVQQAAKERDMKVKKMAASKKAEMRKLEEQLEALRMQEPPVPETPPAAEEQPLEEPQEEKKLAPKQATLDFF
What is the function of this protein?
Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.
What are the official names of this protein?
Replication factor C large subunit, RFC large subunit, Clamp loader large subunit.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family. RfcL subfamily.
Protein: ATPF_CORU7
Sequence: MTNTFFLAAETLPLEEPINPLIPPLYDIVWSIIPFAVILFVFAKVVLPKFQEVLTQREDKIEGGIQRAEAAKAEAQEALEKYNKQLAEARTEAAQIRDDARSQGQKIIADMKTQATEESNRIVEAGNKQLEANRASVVADLRKEMGENSINLAERLLGEQLNDDVKRSGTIDNFLAGLDNVGTAGK
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RS13_BREBN
Sequence: MARIAGVDLPREKRVEVALTYIFGIGRPTSQKILSATGVDMNTRVRDLTEDEVNKLREYIDKTVKVEGDLRREISLNIKRLMEIGCFRGIRHRRGLPVRGQRSKTNARTRKGPRRTVANKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: GTCA_LISMN
Sequence: MSKIRQLLNKIPWYTDQVHSIFMYLIMGGFTTIINIVTFWLCTYILNWDYRIANTIAFIASVLFAYFSNKKFVFDSYTPTWKDRLREASSFFGFRCLTYIIDILVMILLISYLSVDELWAKIWTNIIVLVLNYVFSKWIIFKVQK
What is the function of this protein?
Involved in the decoration of cell wall teichoic acid with galactose and glucose.
What are the official names of this protein?
Cell wall teichoic acid glycosylation protein GtcA.
What is the protein family that this protein belongs to?
Belongs to the GtrA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RECR_CHLT2
Sequence: MLKYPDYISKLISFLKKLPGIGFKSAEKIAFELLEWDPSQIEAMALALQEFSTSHATCSNCFCLKISQTSPCNFCSESRDSSSLCIVATPKDVFALEKSKIFKGHYFVLGNLLSPITGKHLSLEKLAILKQRIEACSPKEMIIALDATLEGDATALFLKQEFSYLPIKISRLALGMPVGLSFDFVDANTLARAFSGRNCF
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: NODM_RHILV
Sequence: MCGIVGIVGHKPVSERLIEALGRLEYRGYDSSGVATIFEGELHRRRAEGKLGNLKTRLKEAPLSGTVGIAHTRWATHGAPTECNAHPHFTDGVAVVHNGIIENFSKLKDALAEVGTKFQTDTDTEVIAHLLTKFRRDGMGCLEAMHAMLKCVEGAFALAILFEDDPATIMVARNGPPLVIGHGDGEMFLGSDAIALAPFTNDITYLNDGDWAVVGKTSVQVFDIEGNVVTRPRHISLATADLVGKGNHPHFMEKEIYEQPEVIARALGHYINVNDSHVTTTSTDIDFAGVESLAISACGTAYLAGLIGKYWFERYARLIVEIDVASEFRYREIPLSPRSAALFISQSGETADTLASLRYCKAHGLRIGAVVNTRESTMAREADAIFPILAGPEIGVASTKAFTCQLAVLAALRIGAGKARGTITDDEEQVLVQSLATLPGVMRQVLNDITPEIELLSRELSHYRDVLYLGRGTSFPLAMEGALKLKEVSYIHAEGYAAGELKHGPIALIDENMPVIVIAPHDRFFDKTVSNMQEVAARGGRIILITDETGASMSKLPTMHTIVLPDVAEIIAPMIFSLPLQLLAYHTAVVMGADVDQPRNLAKSVTVE
What is the function of this protein?
Involved in the production of the root hair deformation (HAD) factor specifically on medicago.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], GFAT, Nodulation protein M.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_BLOFL
Sequence: MAKLRDYYKSHVVYDLMREFKYKSVMQVPKINKITISMGVGKSIINKKFLERAIEDLEMISGQKPVITKARKSIASFKIRQGQEIGCKVTLRRKRMWEFFERLISIAIPRIRDFRGLSIKSFDGYGNYTMGIREQIIFPEINYDTIDGIRGMNITITTNAVSDKEAYVLLRAFRFPLKNNDSIYTSTEEH
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: RNC_STRR6
Sequence: MKELQTVLKNHFEIEFADKKLLETAFTHTSYANEHRLLKISHNERLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKLGKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITDYKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQEAAKNAVEKGLDSCI
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_TROW8
Sequence: MASTSDIRNGVVLNINGQLNTVIEFQHVKPGKGGAFVRTKLKNILTGKVVDKTFNAGASVVLENVDRRDCTYLYRDADSFVFMDLADYDQIRLTASQVASAANYLSDNQKVVIATHNNAPLYVDLPPSVVLAVTHTEPGVQADRSTGGTKPATLETGYQIQVPLFITVGTRIRVDTRTGAYIGKA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DLT_ORYSJ
Sequence: MLAGCSFSSSRHQMSTAQRFDILPCGFSKRGSRGDGAAPRVAGDARSGATTCSFRTHPAPPVTQSVSWGAKPEPGGNGNGAHRAVKRAHDEDAVEEYGPIVRAKRTRMGGDGDEVWFHQSIAGTMQATAAGEGEEAEEEKVFLVPSAAAFPHGMAAAGPSLAAAKKEEYSKSPSDSSSSSGTDGGSSAMMPPPQPPEFDARNGVPAPGQAEREALELVRALTACADSLSAGNHEAANYYLARLGEMASPAGPTPMHRVAAYFTEALALRVVRMWPHMFDIGPPRELTDDAFGGGDDDAMALRILNAITPIPRFLHFTLNERLLREFEGHERVHVIDFDIKQGLQWPGLLQSLAARAVPPAHVRITGVGESRQELQETGARLARVAAALGLAFEFHAVVDRLEDVRLWMLHVKRGECVAVNCVLAMHRLLRDDAALTDFLGLARSTGATILLLGEHEGGGLNSGRWEARFARALRYYAAAFDAVDAAGLPEASPARAKAEEMFAREIRNAVAFEGPERFERHESFAGWRRRMEDGGGFKNAGIGEREAMQGRMIARMFGPDKYTVQAHGGGGSGGGEALTLRWLDQPLYTVTAWTPAGDGAGGSTVSASTTASHSQQS
What is the function of this protein?
Probable transcription factor that acts as positivie regulator of brassinosteroid (BR) signaling (PubMed:19220793, PubMed:22685166).  Functions downstream of BRI1 and GSK2 to modulate BR responses.  Acts as a direct target of GSK2 kinase to mediate BR responses (PubMed:22685166).  Involved in feedback inhibition of BR biosynthetic genes.  Repressed by BZR1 (PubMed:19220793).  Cooperatively functions in a transactivating complex with SMOS1 to enhance the transcription of the SMOS1 target PHI-1, and regulate plant organ size (PubMed:28069545).  Interaction between SMOS1 and DLT is a crosstalk point for auxin and brassinosteroid signaling (PubMed:28069545).
What are the official names of this protein?
Protein DWARF AND LOW-TILLERING, GRAS family protein 32, OsGRAS-32, Protein SMALL ORGAN SIZE 2.
What is the protein family that this protein belongs to?
Belongs to the GRAS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DNAJ_SALG2
Sequence: MAKRDYYEILGVSKTAEEREIKKAYKRLAMKYHPDRNQGDKEAEAKFKEIKEAYEVLTDAQKRAAYDQYGHAAFEQGGMGGGFGGGFNGGADFSDIFGDVFGDIFGGGRGRQRAARGADLRYNMDLTLEEAVRGVTKEIRIPTLEECDVCHGSGAKAGTQPQTCPTCHGSGQVQMRQGFFAVQQTCPHCQGRGTLIKDPCHKCHGHGRVEKSKTLSVKIPAGVDTGDRIRLAGEGEAGEHGAPAGDLYVQVQVKQHPIFEREGNNLYCEVPINFAMAALGGEIEVPTLDGRVMLKVPSETQTGKLFRMRGKGVKSVRGGAQGDLLCRVVVETPVGLSEKQKQLLKDLQESFGGPTGEKNSPRSKSFFDGVKKFFDDLTR
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROA_KLEP3
Sequence: MLEQMGIAAKAASWQLALLSSREKNQVLEKIADYLEAQTDDILRANAEDLAEARANGLSEAMLDRLALTPARLSGIANDVRQVCNLADPVGQVIDGGLLDSGLRIERRRVPLGVIGVIYEARPNVTVDVASLCLKTGNAAILRGGKETWRTNAATVKVIQQALQECGLPAAAVQAIESPDRALVGEMLKMDKYIDMLIPRGGAGLHKLCREQSTIPVITGGIGVCHIFVDETAEIAPALKIIVNAKTQRPSTCNTVETLLVHRNIADTFLPALSKQMAESGVTLHAAPSALPALQNGPAKVEPVKAEQYDDEYLSLDLNVKVVADMDEAIAHIREHGTQHSDAILTRTLRNANRFINEVDSSAVYVNASTRFTDGGQFGLGAEVAVSTQKLHARGPMGLEALTTYKWIGFGDDTIRA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MASZ_RHILV
Sequence: MSRVDKNGLAIETVLHDFLVEEVLPGLAVDADKFFADFSAIVHDLAPKNCALLAKRDELQVKIDDWYRRHGAPADMDEYQSFLREIGYLLPEGSDFQVSTQNVDPEIASIAGPQLVVPVMNARYALNAANARWGSLYDALYGTDAIPESDGAEKGKSYNPKRGEKVIAWVRDFLDTSAPLQDCRWKDVGSFAVKDGALVVRSIDGEQAMLTDGKHFAGYRGDAAAPTHILLKNNGIHIEIVIDAATTIGKADSAHISDVWLESAITTIMDCEDSIAAVDAEDKVVVYRNWLGLMKGDLQEEVAKGGTSFIRTLNPDLQYAGPDGAAFEVHRRSLMLVRNVGHLMTNPAILDRDGNEVPEGIMDAAITGLIALYDIGPSGRRKNSRTGSMYVVKPKMHGPEEVAFAVEIFSRVEDALGLPRNTIKMGIMDEERRTTVNLKECIRAARERVVFINTGFLDRTGDEIHTSMEAGPMIRKGDMRQAAWISAYENWNVDIGLECGLAGHAQIGKGMWAMPDLMAAMLEQKIAHPKAGANTAWVPSPTAATLHATHYHRVNVARVQQGLKDRARAKLSDILSVPVAVRPNWTPEEIQRELDNNAQGILGYVVRWVDQGVGCSKVPDINNVGLMEDRATLRISAQHMANWLHHKVVTEAQIIETMRRMAAVVDRQNASDPAYRPMAGNFDDSIAFQAALDLVLKGREQPNGYTEPVLHRRRLELKAKQAA
What is the function of this protein?
Involved in the glycolate utilization.  Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
What are the official names of this protein?
Malate synthase G.
What is the protein family that this protein belongs to?
Belongs to the malate synthase family. GlcB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_DANRE
Sequence: MADTGLLEALLQRVEQLDGGVDSQDVSAALGVDHQLVVGAVKSLQALGEVISAEQKSSKHWELTGEGREIAEQGSHEARVFNAIPAEGLPQNQLMKMASGKVGFSKAMSNKWIRLDKAHEGGPRVFRTVESIEDTVRDKLQLVQNGQSAKLEEKEKNELKKRKLLAEVTVKSYWITKGNSFSTTITKQETELTPEMIASGNWKEKKFKPYNFEAMGVAPDCGHLHPLMKVRTQFRQIFLEMGFTEMPTNNFIESSFWNFDSLFQPQQHPARDQHDTFFISDPALAHEFPRDYLERVKKVHSEGGYGSQGYKYDWKIEEAQKNLLRTHTTAVSARMLYKLAQQEKFTPVKYFSIDRVFRNETLDATHLAEFHQIEGVVADYGLTLGNLMGVLHQFFTKLGITKLRFKPAYNPYTEPSMEVFSYHEGLKKWVEVGNSGVFRPEMLLPMGLPEGVSVIAWGLSLERPTMIKYGINNIRELVGHKVNLQMVYDSPICRLDS
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPX_YERP3
Sequence: MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVSPHRDRSSLPTPHEIRHHLDDYVIGQEPAKKVLAVAVYNHYKRLRNGDTSNGIELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTIAAVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVIGQRINTGSGIGFGAVVKGQSEKATEGELLSQVEPEDLIKFGLIPEFIGRLPVVATLSELSEDALIQILKEPKNALTKQYQALFSLEGVELEFRDEALTAIAKKAMARKTGARGLRSIVEGALLDTMYDLPSMDSVEKVVVDESVIAGQSAPMLIYGQPEAQASGE
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: HPAB_PSEAE
Sequence: MKPEDFRASATRPFTGEEYLASLRDDREIYIYGDRVKDVTSHPAFRNAAASMARLYDALHDPQSKEKLCWETDTGNGGYTHKFFRYARSADELRQQRDAIAEWSRLTYGWMGRTPDYKAAFGSALGANPGFYGRFEDNAKTWYKRIQEACLYLNHAIVNPPIDRDKPVDQVKDVFISVDEEVDGGIVVSGAKVVATNSALTHYNFVGQGSAQLLGDNTDFALMFIAPMNTPGMKLICRPSYELVAGIAGSPFDYPLSSRFDENDAILVMDKVFIPWENVLIYRDFERCKQWFPQGGFGRLFPMQGCTRLAVKLDFITGALYKALQCTGSLEFRGVQAQVGEVVAWRNLFWSLTDAMYGNASEWHGGAFLPSAEALQAYRVLAPQAYPEIKKTIEQVVASGLIYLPSGVRDLHNPQLDKYLSTYCRGSGGMGHRERIKILKLLWDAIGSEFGGRHELYEINYAGSQDEIRMQALRQAIGSGAMKGMLGMVEQCMGDYDENGWTVPHLHNPDDINVLDRIRQ
What is the function of this protein?
Oxygenase component of the 4-hydroxyphenylacetate (HPA) 3-hydroxylase.  Catalyzes the hydroxylation of 4-hydroxyphenylacetate to form 3,4-dihydroxyphenylacetate, using FADH(-) provided by the reductase component HpaC to activate oxygen.  To a lesser extent, can also use reduced FMN (PubMed:20000468).  In vitro, has hydroxylation activity toward tyrosol and various cinnamic acid derivatives, catalyzing the hydroxylation of p-coumaric acid, caffeic acid, ferulic acid, and coniferaldehyde (PubMed:23666444).
What are the official names of this protein?
4-hydroxyphenylacetate 3-monooxygenase oxygenase component, HPA 3-monooxygenase oxygenase component, p-hydroxyphenylacetate 3-hydroxylase large component, HPAH large component.
What is the protein family that this protein belongs to?
Belongs to the FADH(2)-utilizing monooxygenase family.
Protein: PUR7_PECCP
Sequence: MQKLAELYRGKAKTVYTTEDPDLLVLEFRNDTSAGDGARIEQFDRKGMVNNKFNHFIMSKLEEAGIPTQMVSLLSDNEVLVKKLEMVPVECVVRNRAAGSLVKRLGIEEGIELNPPLFDLFLKNDAMHDPMVNESYCKTFGWVNEENLARMKELSYKANDVLSKLFGDAGLILVDFKLEFGLFKGEVVLGDEFSPDGSRLWDKETLNKMDKDRFRQSLGGLIEAYEEVAHRIGVKLD
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: KEL1_YEAST
Sequence: MAGFSFAKKFTHKKHGKTPSDASISDQSREASLSTPPNEKFFTKQETPQKGRQFSQGYHSNVNKTSSPPMFARKQVSESRIQPSAVPPQQRNVSGPSTTLHKQLSKQREYTVWNRIKLQNSPFPRYRHVASAYVTDKNQIYVIGGLHDQSVYGDTWILTAFDNATRFSTTTIDISEATPPPRVGHAAVLCGNAFVVFGGDTHKVNKEGLMDDDIYLLNINSYKWTVPAPVGPRPLGRYGHKISIIATTQMKTKLYVFGGQFDDTYFNDLAVYDLSSFRRPDSHWEFLKPRTFTPPPITNFTMISYDSKLWVFGGDTLQGLVNDVFMYDPAINDWFIIDTTGEKPPPVQEHATVVYNDLMCVVGGKDEHDAYLNSVYFLNLKSRKWFKLPVFTAGIPQGRSGHSLTLLKNDKILIMGGDKFDYARVEEYDLHTSDIDMQRGTIVYTLDLARIKDLCPGVMDVPTDTPTPRNGNLDLATPVTPTSHQTKNMNVPISAAPLASAPSPAPKDFSDADRLNREVHNRNVSTEHQNQSHPVNSESHLIAEPNILTPYVPSESSQTPVMKITSNKPFDTPTIQKEPDLSETMDPTVGNQRIPSSIYGDNLTPANQIKNNSPILETLPSNEIKTPQNGNIEEIKHLPDADEKIDSTTTFDQEINGDKLGTSSMSKVEEDGNVADEDDEIGVAQMASSPSKDQFKIKHYNESSELSQNNTEIDKLSEPVDITIKKSDTAGHDSANHVIDASDEKNVSPMGDVPTDTKNEEASVPINRDATTEVVDRALFEKLRSELQSLKELTHEKALEAGAHIKELETELWQLKSQKNSGTTKEIDELDSVRLQSKCEILEADNHSLEDKVNELEELVNSKFLDIENLNEVIQFQNEKIKSLELEPNYKEKLEELQIEHENLSRENERLKNESKQHNEDIINNVANYSSQLGSLISHWKENRANSSFLESSSSLISVSDENGEKTVGEPYGDQSRHHRVVINKLTNRLDDLLERSQELTISKEKLSSEYHALKMEHSSLSQDVLVKENEIKKIQNDYKESISSMDSASKALMVSQRELEKYKSLNKKLIDELDELKFKNGVCSENFENGLRSTEESSNNVKNSNSIRENQFNIKINDLKAELFITNQERDDLKSEVLELKKRLLNLENNTKQVNEDADSDLL
What is the function of this protein?
Has a role in cell morphogenesis and cell fusion and may antagonize the PKC1 pathway.
What are the official names of this protein?
Kelch repeat-containing protein 1.
Protein: 7DMAW_ASPFU
Sequence: MSIGAEIDSLVPAPPGLNGTAAGYPAKTQKELSNGDFDAHDGLSLAQLTPYDVLTAALPLPAPASSTGFWWRETGPVMSKLLAKANYPLYTHYKYLMLYHTHILPLLGPRPPLENSTHPSPSNAPWRSFLTDDFTPLEPSWNVNGNSEAQSTIRLGIEPIGFEAGAAADPFNQAAVTQFMHSYEATEVGATLTLFEHFRNDMFVGPETYAALRAKIPEGEHTTQSFLAFDLDAGRVTTKAYFFPILMSLKTGQSTTKVVSDSILHLALKSEVWGVQTIAAMSVMEAWIGSYGGAAKTEMISVDCVNEADSRIKIYVRMPHTSLRKVKEAYCLGGRLTDENTKEGLKLLDELWRTVFGIDDEDAELPQNSHRTAGTIFNFELRPGKWFPEPKVYLPVRHYCESDMQIASRLQTFFGRLGWHNMEKDYCKHLEDLFPHHPLSSSTGTHTFLSFSYKKQKGVYMTMYYNLRVYST
What is the function of this protein?
Catalyzes the prenylation of L-tryptophan at the C-7 position of the indole moiety.  The enzyme is specific for dimethylallyl diphosphate (DMAPP) as prenyl donor.  Accepts also D-tryptophan, typtophan-derivatives with modifications at the side chain or the indole ring, and linear and cyclic dipeptides such as H-L-Trp-L-Gly-OH or cyclo-L-Trp-L-Gly as substrates, however with lower efficiency.  Also has tryptophan aminopeptidase activity towards linear peptides with a tryptophanyl moiety at the N-terminus.  Dipeptides are better substrates than peptides with 3 or more amino acids.  Enzymatic rate constants however are much higher for the prenyltransferase activity than for the aminopeptidase activity.
What are the official names of this protein?
7-dimethylallyltryptophan synthase, 7-DMATS, Tryptophan aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the tryptophan dimethylallyltransferase family.