PharMolix/UniProtQA huggingface dataset:
Protein: ISPT1_CORDI
Sequence: MRTLKKFSLRDLAYNAAYPFYEKRLMREIQGVRQPEHVAIMCDGNRRWAREAGFADVTHGHRVGAKKIGEMVRWCAHTDVELVTVYLLSTENLGRASDELQMLFDIIGDVVDELASPETNCRLRLVGHLDLLPDDVSRRLTQAQDSTNDNTGVFVNVAVGYGGRQEIVDAVRELIDAEAAAGTTATEMAEKISVDSISKHLYTSGQPDPDLVIRTSGEQRLSGFLLWQAAYSEIWFTDTYWPAFRRVDFLRALREYSKRSRRFGK
What is the function of this protein?
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
What are the official names of this protein?
Isoprenyl transferase 1.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: PYRH_SHIBS
Sequence: MATNAKPVYKRILLKLSGEALQGTEGFGIDASILDRMAQEIKELVELGIQVGVVIGGGNLFRGAGLAKAGMNRVVGDHMGMLATVMNGLAMRDALHRAYVNARLMSAIPLNGVCDSYSWAEAISLLRNNRVVILSAGTGNPFFTTDSAACLRGIEIEADVVLKATKVDGVFTADPAKDPTATMYEQLTYSEVLEKELKVMDLAAFTLARDHKLPIRVFNMNKPGALRRVVMGEKEGTLITE
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y569_ARCFU
Sequence: MPPTRKISIRLTEKYYTKLELLVESGEFTSVSEAVREAVKLLLEKYKEQLESIAQMDTYR
What are the official names of this protein?
Uncharacterized protein AF_0569.
Protein: Y889_METJA
Sequence: MVGFMIALSVSSGYLLDNNYSEYSYYILDNDEDFLVFVICDEPNTLKCGFRISEIFSRVFCNAVYNNRYITNLKNLIEVGIYEALENMDKFLKQKGLDYNDLNVSIAGGVYRNGKLMLFSLGNSPVFVVDKDYYLYCPFDLNKNYNLKDWKKFIKFSEVIENPKSVVACSNKLDGKVFKFKNENNKLIAEPFKYRIIQLINSIISNRENIDKIKEELKTDLNLKDNTPLFVASFDEKPINDELVKVGKPKLKVRGCTPILSKKKEETSPHIEPKIIKNMVLAFILILILIFGLFVMLSHNNLNGGNNSDIVNNSSYQVNTSKISIITVNNENKSTNISLNPIQTVKTVSSLNNLDLNNTITKSKNKDSLKILVKFQVGEISKDIKKLPISIMFPEQGYYYISIKSENSNLKLIDVENGEVVYKNTTLIELFEKIDGKEKTYNLIVEYNGSEIPSEKGINISIFEIKIIK
What are the official names of this protein?
Uncharacterized protein MJ0889.
Protein: ATG5_ASPOR
Sequence: METQATLNSIQKAVWDGRLPLQIRLAPSESRIYDQTDPYLISYPRISYLPSLLPRLRAFFASSLIDPSSNAHDGWFSFEGVPLKWHLPIGLLYDLYAGADPASKGTAESEDAGWDIDDQDNPLPWRLVVHFSDWPDEELVRLDAEGMVMNDAFINSVKEADFLRNGTAKGIMSLSKEDSSGLWKSVQNVELSSFQRISNILLPPLNQPFRNIPIRIFLPLPPDSGSPSLKIVQSPVPPLIPPSSVAASQLALSRSSITPQTQTIGSALHSLLPNLFPSRRTPVLAKPVLHGAAVPMSAPVEELVRSSAYGDGWLYVVIRMMG
What is the function of this protein?
Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.  Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation.  Required for selective autophagic degradation of the nucleus (nucleophagy).  Also required for mitophagy, which eliminates defective or superfluous mitochondria in order to fulfill cellular energy requirements and prevent excess ROS production.  Conjugation with atg12, through a ubiquitin-like conjugating system involving atg7 as an E1-like activating enzyme and atg10 as an E2-like conjugating enzyme, is essential for its function.  The atg12-atg5 conjugate acts as an E3-like enzyme which is required for lipidation of atg8 and atg8 association to the vesicle membranes (By similarity).
What are the official names of this protein?
Autophagy protein 5.
What is the protein family that this protein belongs to?
Belongs to the ATG5 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: VPP4_HUMAN
Sequence: MVSVFRSEEMCLSQLFLQVEAAYCCVAELGELGLVQFKDLNMNVNSFQRKFVNEVRRCESLERILRFLEDEMQNEIVVQLLEKSPLTPLPREMITLETVLEKLEGELQEANQNQQALKQSFLELTELKYLLKKTQDFFETETNLADDFFTEDTSGLLELKAVPAYMTGKLGFIAGVINRERMASFERLLWRICRGNVYLKFSEMDAPLEDPVTKEEIQKNIFIIFYQGEQLRQKIKKICDGFRATVYPCPEPAVERREMLESVNVRLEDLITVITQTESHRQRLLQEAAANWHSWLIKVQKMKAVYHILNMCNIDVTQQCVIAEIWFPVADATRIKRALEQGMELSGSSMAPIMTTVQSKTAPPTFNRTNKFTAGFQNIVDAYGVGSYREINPAPYTIITFPFLFAVMFGDCGHGTVMLLAALWMILNERRLLSQKTDNEIWNTFFHGRYLILLMGIFSIYTGLIYNDCFSKSLNIFGSSWSVQPMFRNGTWNTHVMEESLYLQLDPAIPGVYFGNPYPFGIDPIWNLASNKLTFLNSYKMKMSVILGIVQMVFGVILSLFNHIYFRRTLNIILQFIPEMIFILCLFGYLVFMIIFKWCCFDVHVSQHAPSILIHFINMFLFNYSDSSNAPLYKHQQEVQSFFVVMALISVPWMLLIKPFILRASHRKSQLQASRIQEDATENIEGDSSSPSSRSGQRTSADTHGALDDHGEEFNFGDVFVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVMNSGLQTRGWGGIVGVFIIFAVFAVLTVAILLIMEGLSAFLHALRLHWVEFQNKFYVGDGYKFSPFSFKHILDGTAEE
What is the function of this protein?
Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).  Involved in normal vectorial acid transport into the urine by the kidney (PubMed:10973252, PubMed:12414817).
What are the official names of this protein?
V-type proton ATPase 116 kDa subunit a 4, V-ATPase 116 kDa isoform a 4, Vacuolar proton translocating ATPase 116 kDa subunit a isoform 4, Vacuolar proton translocating ATPase 116 kDa subunit a kidney isoform.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase 116 kDa subunit family.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Note=Localizes to the apical surface of alpha- intercalated cells in the cortical collecting ducts of the distal nephron (PubMed:10973252). Localizes to the basolateral surface of beta-intercalated cells in the cortical collecting ducts of the distal nephron (By similarity).
Protein: RUVC_HELAH
Sequence: MHILGIDPGSRKCGYAIISYASNKLSLITAGFINITTTHLQEQILDLIEALDCLLDRYEVHEVAIEDIFFGYNPKSVIKLAQFRGALSLKILERVGNFSEYTPLQVKKALTGNGKAAKEQVAFMVKRLLHITSEIKPLDISDAIAVAIMHAQRLKLY
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: GLGA1_BRADU
Sequence: MDDFVRVGGLGAVSAALPRALRPFADIRIMLPGYRDIIEQLTHIQIVGRCPSFADLPACSLGRAATKDGLPVYVLLCSQLYDRPGNPYGDESGRDWPDNDIRFARFASAAAELAMGKLDKNWAADLIHANDWQASLVPAYLAWRGAKLPSILTIHNLAYQGLFPKDSLRRIGAPESAFHIDGLEFYDQVSFLKAGLVYASHLTTVSGTYAREITTAEFGCGLEGLLRLRSDAAELTGILNGIDESWDPRSCAQLAQQFGAGDWVGKKANADYVRKQFGLAVSRGPMFGIVARLVHQKGIDLVLSAADEIIDAGGQIVVTGSGEPALEQALIDAHRRRPDAIGVAIGFNDAQARRIFAGSDFTLMPSRFEPCGLSQMYAQRFGSLPIGHQTGGLAETITDGETGFLFSRPSHESFLGGVRRAFEAFMAQDQLDSMRRSAMGRSFSWSISADSYSALYRKLAAV
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase 1, Starch [bacterial glycogen] synthase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: CE57L_XENTR
Sequence: MESLSKESYLSSFHQFPSYAPLPDHIKFESVSSKKIQCSALENISPHQYDILQAPNSRALISALKTLQEKICRLELEKTHARDRLTNLTRVAGEHKKVLESEKQSAELAAKEATNQQNDIGKQLNNAKQRCSLLEKQLDYMKEMMENADTQKTTIHEHQMLTQKEQKEIQSKLKKLEVLEKMCTRLSATHKSAETKIQHLEEKLSVEEQNRKALQDKAAQVQTSLEVNRILLSSASAQNSTQRKVKKKKQSKLKNSVSKEPPSKCFYPKAGELPFVAGKSTTSSHSLSANVQNVLHMMKHHSPQVSQKNPKTAEHKPSVLPGGSRTIPTRLISSFTGDNLSDILLALQDELGQMSFEHQELLRHINETKNTDMREDLERELDYVVKQMEIKSDQIMKLKRHQLNVNKLKKTAKLLKEQPRPTSVTKLAADKQNTGAKDPSTPRRKGDLADGSGTPNSKASLELLKSVRKIQMTLKKDDIMWEK
What is the function of this protein?
Required for spindle microtubule attachment to both kinetochores and centrosomes.  Also functions to tether minus-ends of spindle microtubules to centrosomes.  May act by forming ring-like structures around microtubules, or by serving as a cross-linker or scaffold at the attachment site (By similarity).
What are the official names of this protein?
Centrosomal protein cep57l1, Centrosomal protein 57kDa-like protein 1, Centrosomal protein of 57 kDa, Cep57, Cep57-related protein, Cep57R.
What is the protein family that this protein belongs to?
Belongs to the translokin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Note=Localizes to spindle microtubules.
Protein: COMPL_BPT5
Sequence: MSLSDLARQIIKEQLDTASRSENNKNTVVYSVETGLKDPTRDGTVAQVSFKFSKPVSQDLLNIRTASILKAVSSSLDLSGDLGALENLIQATAGKKSSVGKKRSTGRVQVNFGDPSDVEDGYSGAVTGASGRFVSNSNMKIILEIVAKEYLIKDMKKAGAPLKFRTGRFANSLKIKDVMLRDSETSKGSPELNVTYNYMTRPYSVFNPAVSTYRRLSLRPYPGARNPQKLIGEAIAKAARDLIHSRYKIKVNQGT
What is the function of this protein?
Stabilizes the tail sheath structure and acts as a connector between the end of tail and the portal vertex of the capsid.
What are the official names of this protein?
Tail completion protein p143, Tail protein p143.
What are the subcellular locations of this protein?
Virion. Note=Part of the tail.
Protein: PURL_AQUAE
Sequence: MERVWEAYGLTEEEYRKILKTLKREPNHVELGVLGALWSEHCSYKSSKKHLKKFPTKAEWVVQGPGENAGVVKIDEKVWVAFKVESHNHPSYIEPFHGAATGVGGIIRDVLSMGARPIALADSLRFGEFNYHETKRLVKGVVSGISFYGNCIGVPTVAGETVFEPSYKTNPLVNAFCLGVIPAGRMYRARATREGQLLFLIGSSTGRDGIFGAVMASGEFSEDVEEKRPNVQIGDPYFGKKLVEAIMEIVEKDLIVGMQDLGAAGLAGSASEIAAKSEKGVELYLENVPLREKDMNPYEILLSESQERMLLVVEEENVEKVKEIANKWHLEGAVVGKITDDDTFRAYYKGELVAELPVSLIVDEAPVYDRPYKEPEYMKEVRNFNQEELPQTDVKEALKKLLSSPNISCKEWVYTQYDYQVGTNTLLIPGHDAAVLRLKWVLRPELTTEKGIAISSEGNGRMVYLNPYEGGKFVVAEVCRNLACVGAKPLAITDCLNFGNPERPEIMWQFVKAVEGMAEACEELGIPVVSGNVSLYNETVEKNEIRNVFPTPIVVGVGVLEKAEKYTPSKVEKESELYLVGNLEENLRLDGSEYLKVIHGLIKGDVPPVDLEKEKILINLLISFNNKELITCAHDVSVGGLLIALLEMVFRTPYGLEVEVYTDERPDVFFFSENPTRVIIGVESDKAEEVKNAVEKAGLEWMYIGKTTEEKKIKVTFNGDTLLEDELEEYEKLWRTSLEKLLGST
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCUP_ECOLC
Sequence: MTELKNDRYLRALLRQPVDVTPVWMMRQAGRYLPEYKATRAQAGDFMSLCKNAELACEVTLQPLRRYPLDAAILFSDILTVPDAMGLGLYFEAGEGPRFTSPVTCKADVDKLPIPDPEDELGYVMNAVRTIRRELKGEVPLIGFSGSPWTLATYMVEGGSSKAFTVIKKMMYADPQALHALLDKLAKSVTLYLNAQIKAGAQAVMIFDTWGGVLTGRDYQQFSLYYMHKIVDGLLRENDGRRVPVTLFTKGGGQWLEAMAETGCDALGLDWTTDIADARRRVGNKVALQGNMDPSMLYAPPARIEEEVATILAGFGHGEGHVFNLGHGIHQDVPPEHAGVFVEAVHRLSEQYHR
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HISZ_BACP2
Sequence: MFMFEKPYGMRDSLPGLYETKKKVRHSLTEVMNGWGYRLMETPTLEFYDTVGVQSAITDTQLFKLLDQNGQTLVLRPDMTGPIARVAASKLHEQAYPLRVGYAANVFRAQEREGGRPSEFEQVGIELIGDGSISADAEVIALVVFALKNAGLNSFKIAIGHVALAETLFVDVLGNTERANVLRRFLYEKNYVGYRQHVKQLPLSSIDKTRLLQLLELRGGREVTERAEEIVVSQEGKEVLAQLKSLWETLEDYGCTEYIRLDLSMVSHMSYYTGILFEVFADHVGSVIGSGGRYDQLLAHFNAPAPATGFGLRLDRLLEALDVKEINEPQEAVIFSKEQRLEAFAFAEKERSKGKKIVLQDLAGIENIDAMTKAFEQVTYFIGARKGEQNG
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AACUH_ASPA1
Sequence: MTAHIGLSAQHVVDSLGHPDGASRPPVSAESLSRASELLQSNHDTWHIFFREATGHNHMAHSILTALALGASPSELERAYTDTEAIQRPIPAVDPMILTRLDADPQALESLLGWSDLYSTFLTYFQSQIDRHGWQSVVTTYVFSETPLAEKLLIKLYEGMYHSLIHLGLGIEFGQPGIIAEALAQAAAHEDGHIDKLLLGVEAAIAAKDDTRTETTVPKSLVQLVDEVRSHPRIWADLRFGDRWNRMRDSIMDRAADELIPIAAQFRIPASGMMMMAGEHADLLTIRTAEMASTAAYLAGASQSARRPRKIDFFLMHTVTASLFFSVFNAQEWIPRAMRVRLVEWKGRLDLAFYAFCKSPELDACVISDYSDDFTRDMDWAALYAAVNQEHDDGHVAKFMRALRHAERLSRPYEQHPVWAEHFPVKGNMWIKLARMALETTRHSPPDFKWIMGTGFDEAWERPDLKLAENRGQQGQSVP
What is the function of this protein?
Baeyer-Villiger monooxygenase; part of the gene cluster that mediates the biosynthesis of the tetrahydroxanthone dimer secalonic acid D (PubMed:30996871, PubMed:33891392).  The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase AacuL (Probable).  The atrochrysone carboxyl ACP thioesterase AacuM then breaks the thioester bond and releases the atrochrysone carboxylic acid from AacuL (Probable).  Atrochrysone carboxylic acid is decarboxylated by the decarboxylase AacuI, and oxidized by the anthrone oxygenase AacuG to yield emodin (Probable).  Emodin is then reduced to emodin hydroquinone by a yet unidentified oxidoreductase (Probable).  A-ring reduction by the short chain dehydrogenase AacuN, dehydration by the scytalone dehydratase-like protein AacuK and probable spontaneous re-oxidation, results in overall deoxygenation to chrysophanol (PubMed:33891392).  Baeyer-Villiger oxidation by the Baeyer-Villiger monooxygenase (BVMO) AacuH then yields monodictyphenone (PubMed:33891392).  Monodictyphenone is transformed into compounds with the tetrahydroxanthone skeleton via methylesterification by the methyltransferase AacuQ, followed by the action of the flavin-dependent monooxygenase AacuC, the isomerase AacuP, and the short chain dehydrogenase/reductase AacuF or AacuD (PubMed:33891392).  AacuF and AacuD should accept the same compound as a substrate but perform the ketoreduction with a different stereoselectivity, thus yielding blennolides B and A, respectively (PubMed:33891392).  In the final step of the biosynthesis, the cytochrome P450 monooxygenase AacuE accepts blennolide B and/or blennolide A to conduct the dimerization reaction to furnish the tetrahydroxanthone dimers, secalonic acids D, B, and F (PubMed:33891392).
What are the official names of this protein?
Baeyer-Villiger monooxygenase AacuH, BVMO AacuH, Secalonic acid biosynthesis cluster protein H.
What is the protein family that this protein belongs to?
Belongs to the AflY oxidoreductase family.
Protein: RM12_CRICR
Sequence: MLPAAAAAASLWAPRLGLRGARLRLARQQVPGVCAARQLSSSSQRRSEALAGAPLDNAPKEYPPKIQQLVQDIASLTLLEISDLNELLKKTLKIQDVGLMPMGGMMPGAVPAAAAAAPEVAEGEDILKQKERTHFTVRLTEAKPVDKVKLIKEIKNYVQGINLVQAKKLVESLPQEIKANVAKAEAEKIKAALEAVGGTVVLE
What is the function of this protein?
As a component of the mitochondrial large ribosomal subunit, it plays a role in mitochondrial translation.  Associates with mitochondrial RNA polymerase to activate transcription.
What are the official names of this protein?
39S ribosomal protein L12, mitochondrial, L12mt, MRP-L12, P2A1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: YIHI_SALSV
Sequence: MKKPTSAPRSKAFGKQRRKTREELNQEARDRKRLKKHRGHAPGSRAAGGNSASGGGNQNQQKDPRIGSKTPVPLGVTEKVTQQHKPKSEKPMLSPQAELDLLETDERLDALLERLEAGETLSAEDQAWVDAKLDRIDELMQKLGLSYDDDEEDDEEDEKQEDMMRLLRGGN
What is the function of this protein?
A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function.  May play a role in ribosome biogenesis.
What are the official names of this protein?
Der GTPase-activating protein YihI.
What is the protein family that this protein belongs to?
Belongs to the YihI family.
Protein: RS19_CLOB6
Sequence: MSRSVKKGPYIQEVLLKRINEMNKNGEKKVLKTWSRSSTIFPQMIGHTIAVHDGRKHVPVYITEDMVGHKLGEFVLTRTYRGHDDKSEKSSRLR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: RS17_HALWD
Sequence: MAIGLNVTEPEVSCADTNCPFHGSLSVRGQTLEGTVASTDMDKTVIVEREYDVRVPKYDRLMKRRSRIPAHAPPCVDLAEGDTVRIAETRPLSKTKSHVVVEQIDTGGAE
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: URE3_KLEP7
Sequence: MELTPREKDKLLLFTAALVAERRLARGLKLNYPESVALISAFIMEGARDGKSVASLMEEGRHVLTREQVMEGVPEMIPDIQVEATFPDGSKLVTVHNPII
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPS_KLEP7
Sequence: MSKRDWLDFEHLVDDEVRDAIKPPSMYKVILVNDDYTPMEFVIDVLQKFFSYDVERATQLMLTVHYEGKAICGVFTAEVAETKVAMVNQYARENEHPLLCTLEKA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: GUC2D_MOUSE
Sequence: MAGLQQGCHFEGQNWTAPHWKTCLPCQGPWRLTVSHLKTVSSISVLSVVFWSVLLWADSLSLLAWARETFTLGVLGPWDCDPIFAQALPSIATQLAVDQVNQDASLLPGSQLDFKVLPTGCDTPHALATFVAHKNIVAAFVGPVNPGFCSAAALLAQGWGKSLFSWACEAPEGGGDLVPTLPSAADVLLSVMRHFGWARWAIVSSHQDIWVTTAQQLATAFRTHGLPIGLVTSLGPGEKGATEVCKQLHSVHGLKIVVLCMHSALLGGLEQTTLLHCAWEEGLTDGRLVFLPYDTLLFALPYGNRSYLVLDDHGPLQEAYDAVLTVSLESSPESHAFTATEMSGGATANLEPEQVSPLFGTIYDAVILLAHALNRSETHGAGLSGAHLGDHVRALDVAGFSQRIRTDGKGRRLAQYVILDTDGEGSQLVPTHILDTSTWQVQPLGKPIHFPGGSPPAHDASCWFDPNTLCIRGVQPLGSLLTLTIACVLALVGGFLAYFIRLGLQQLRLLRGPHRILLTSQELTFLQRTPSRRRPHVDSGSESRSVVDGGSPRSVTQGSARSLPAFLEHTNVALYQGEWVWLKKFEAGVAPDLRPSSLSFLRKLREMRHENVTAFLGLFVGPGVSAMVLEHCARGSLEDLLQNENLRLDWTFKASLLLDLIRGLRYLHHRRFPHGRLKSRNCVVDTRFVLKITDHGYAEFLESHCSSRPQPAPEELLWTAPELLRGPGKATFKGDVFSLAIILQEVLTRDPPYCSWGLSAEEIIRKVASPPPLCRPLVSPDQGPLECIQLMQLCWEEAPDDRPSLDQIYTQFKSINQGKKTSVVDSMLRMLEKYSESLEDLVQERTEELELERRKTERLLSQMLPPSVAHALKMGTTVEPEYFDQVTIYFSDIVGFTTISALSEPIEVVGFLNDLYTLFDAVLDSHDVYKVETIGDAYMVASGLPRRNGNRHAAEIANLALDILSYAGNFRMRHAPDVPIRVRAGLHSGPCVAGVVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVSQSTVQALLSLDEGYKIDVRGQTELKGKGLEETYWLTGKVGFCRPLPTPLSIKPGDPWQDRINQEIRTGFAKARQGLAEPRKSGEAGPGP
What is the function of this protein?
Functions as an olfactory receptor activated by urine odorants, uroguanylin and guanylin and as well by the volatile semiochemicals carbon disulfide (CS2) and carbon dioxide (CO2) (PubMed:17724338, PubMed:17702944, PubMed:20637621).  Has guanylate cyclase activity upon binding of the ligand (By similarity).  Activation of GUCY2D neurons leads to the cGMP-dependent activation of the CNGA3 channels, membrane depolarization and an increase in action potential frequency (PubMed:17724338, PubMed:20637621).  Signaling pathways activated by GUCY2D may trigger social behaviors such as acquisition of food preference (PubMed:20637621).
What are the official names of this protein?
Guanylate cyclase D.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Cell projection, cilium membrane; Single-pass type I membrane protein.
Protein: LPXK_SACD2
Sequence: MSAALAKAIERRWYSRPGILWLLYPLALLFRLLSYFRRRSQTQSSVKFAVPVCIVGNIAIGGTGKTPTIIALVHALAEQGITAGVVARGYGASLAKDEVRVLDANATAAMVGDEPLLIYKRTGCVVAVGSNRVAACETLLKSHAVDVILSDDGMQHYKLGRDLELALVDGERVFGNGQLLPVGPLREHPKRLQSVNWLLVNGGSAEHVNARLQALEAINAAELSSKPNKLNKTPAPVFAQLEAVKLVNLATGKTLLLQNITELGAFVAVAGIGNPARFFKTLQSTGITGFDTFSYPDHHKFTSADFRQFDNKAIVMTEKDAVKCTPFATDAMWYVPVDLKLPQTFIADFCAQIRKVIALYN
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: GLXB_RHIME
Sequence: MCGIVGLFLKDSRLEPQLGQLLSDMLITMTDRGPDSAGLAIYGSATEGKAKVTIQSAKPEIDFADLERDLAEAGVPARVAVKSTHAVVAIAAARLADVRAVLAAIRPDVRIMGAGDSVEIYKEVGLPKDVVARFDVRSMGGSHGIGHTRMATESAVTTLGAHPFSTGSDQCLVHNGSLSNHNNLRRELIREGIAFETQNDTEVAAAYLTAEMAKGKDLGQALTGALDDLDGFFTFVVGTKSGFGVVRDPIACKPAVMAETDRYVAFGSEYRALVNLPDIESARIWEPEPATVYFWDHQKAA
What are the official names of this protein?
Glutamine amidotransferase-like protein GlxB.
Protein: MIAB_BUCAP
Sequence: MKYIYIKTWGCQMNEYDSSMITVFLEKTGRYLITKEVEKADILILNTCSIREKAQEKVFHQLGRWKKLKNKKPDVIIAVGGCVATQEGKEIFKRANYVDIVFGTQTLHKLAQMIDKVEKNRRFMIDISFPQLEKFNYSLEPKKTGYTASISIMEGCNKYCSFCVVPYTRGHEISRPSDDILLEISILAENGVREINLLGQNVNAYRGRTFNGKICFFSELLRLVSEIDGIDRIRFTTSNPLEFTDDIIEVYQDTPKLVSFLHLPVQSGSNRILQLMKRSYTTEEYEKIIEKLILARSNIQISSDFIVGFPSESEEDFQKTINFIKKINFDMSFSFIYSSRPGTPASEMKDNIDLQEKKKRLYTLQNCINKQTMSWSRKMLKSTQSVLVEGVSKKNIMELYGKTENNRIVTFKGSHKMIGKFIKLKIKKVHTHSLQGELI
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZIPA_YERPY
Sequence: MMQDLRLILIVVGAIAIIALLLHGLWTSRKERSSLFRDRPVKRTKQERVETPIESLDEGVGEVRVRTSHPQEKPSFNHLDDDDDEVPVIQHAETKSAQVKTASRQAPFASVQTDYDDPLLGGLSAEQPPHDLSRDPLLGKADESYSQPQHAEPPHVEKPAHQVAPQQHVESQQEPVAPAPEAKPQKLKETVLVLHVAAHHGGVIGGEVLLQSVLQSGFQFGEMGIFHRHLSPAGSGPVLFSLANMVKPGSFDPDTMSDFSTPGVSMFMMVPSYGDANQNFKLMLQSAQRIADDVGGVVLDDERRMMTPQKLESYKARIREVLDANTIA
What is the function of this protein?
Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring.  Also required for the recruitment to the septal ring of downstream cell division proteins.
What are the official names of this protein?
Cell division protein ZipA.
What is the protein family that this protein belongs to?
Belongs to the ZipA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type I membrane protein. Note=Localizes to the Z ring in an FtsZ-dependent manner.