PharMolix/UniProtQA huggingface dataset:
Protein: NUON_ACIB5
Sequence: MNFTVSFSTLMPLAPVMIVALTAVVVMLLISIKRNHNLIATTSVVGLNLAALYILLELFGGKFVPANVMGMFMVDPFTMFYQFMILVASLACCTLSHAYIETYKDNREELYLLLLASVAGAMLMVASSHYASFFISLELMSIPVYGLLAYTYQRSQSLEAGIKYLVLSATASAMLLMGMAYIYAYTGSLSFYDSVQALFGAIKQPMVLLGLALIIFAVAFKLSLAPFHKWTPDVYAGAPAPMATFLATAAKVATIGLFVRYLLASGAIMVNSLVTVLTIIAVLSILVGNLLAVRQVNLKRILGYSSIAHFGYLLIALISMTYASLGSVTVYVVTYVLTTIGAFGAVALMSSPYNNVDEAQSLADYRGLFWRRPVLTATLTVMMLSLAGIPLTAGFIGKFLVVMAAVTTQHWFLAAMIIVGSGIGLYYYLRVMVVMYMTPPETPRIDADAHWGQKVGGLMVLAAAALVIILGVYPDPMINLALKAEILSPLHFMLSQQQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ACP_AKKM8
Sequence: MSDNSIEEKVRSIIVDQLGVESDKVTADAKFIEDLGADSLDTVELVMAFEENFDIEVPDEEAEKLQSVADVVAYIEKVQG
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_OLEA2
Sequence: MTKKKSSGGALIAQNKKARHLYELLEFFEAGIALAGTEVKSLRAGQVSFTDSYVTIHNNEAWIVGMHIAPYANAGYVQHDPDRDRKLLLHAREIDTLRARVEQKGLTVVPVKLYFKNSRVKLEIAVGRGKKLHDKRQDIKQRDVERETRREIMRH
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: PSBK_TRICV
Sequence: MESLLLARLPEAYVVFSPIVDVLPIIPVFFLLLAFVWQAAIGFR
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein K, PSII-K.
What is the protein family that this protein belongs to?
Belongs to the PsbK family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: TILS_SHEWM
Sequence: MTEPSFNTSALIEESIKSAKINVGAKLVLAYSGGVDSEVLAQGLSLYAKSHPEFRYLLVHVHHGLSRNADAWVTHCQKQALDYQLPIEVVQVQVKTGPRLSIEAEARRARYKAITSLMDSADVLLTAHHLDDQLETVLLALKRGLGPKGLSAMGALQVFDGDKQLLRPLLNVSREQIEAKAASLSLPHIEDESNTDDKYDRNFLRLQIIPKLKSRWSAIATTASRSAALCAQQQAVIDDEVSARLPNFIELVPYGEGTALNLDLLSHQTPNWQALLLRGYIESSGFAPVSQIQLEQLLSQLLTAKPDANLEVRIADMLVRRFREKAYLSSYRPHKPKSLESIELTLESEVHFVQEINIPLLSNIRVEVLEDDGGERVRLPLIEEKVSVRFSAVGSLRCHPHNRQKGRELKKLWQEYGVPPWERERVPLIFYNEKLVCAVGYWVEHSFQSAEHETGLRFSIAIVSNECESI
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y909_PASMU
Sequence: MNEKRLFTEAQTENEAVDFTPKREFHGEMHIEKDEPVIEDRFVEQTFEHIVQPRSRWWKTGLALTALLFCFAVIAQSIQWLVDTWQQNQWIYFVFSLVTCLVVLLGVSSLGKEWLRLVKLKKRLSLQQKSQQILRESAVNLGQDFCAEKHQQIKALCTEMAQMLKLSSEDPGLIQWQNQLHDAYSAQEVAHLFSQTVLHPFDVQIKKLISKSALEAAVIVAVSPLAVIDMFFLSWRNIRLVNQIAQIYGIELGYWSRLRLLKMVLLNLAFAGATEVVQDIGLDWLSQDLTAKLSARAAQGIGVGLLTARLGIKAMEFCRPLAFQAGEKPRLNHIQQELLGQLRSTFFRSNKTKVKQQV
What are the official names of this protein?
UPF0283 membrane protein PM0909.
What is the protein family that this protein belongs to?
Belongs to the UPF0283 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ARGD_LACLA
Sequence: MTNLFENYGRLPFSLIKGEDQYLFDDRGNKYLDFTSGIGVMNLGYSFEKGKVAVKAQLDSLSHLSNLYQNPLQEDVAEKLSQNHSYKAFFCNSGTEANEAALKLTHLIKKDQKILAFTDGFHGRTFGAMSATMQEKIQAGFSPLLPNFVASPFNDVVALEQILEKEKIGAIIFEIIQGEGGVLPISPDFVEALKSCQQKGILLIIDEIQTGIGRTGKLFAFEHFDFEPDIFTLAKALANGIPTGAMLAKNKYASYFSAGKHGSTFGGNPLAMASANEVLKEIDSDFLEKVTDKGIFFLKLLTEKLSVKATVKSIRGLGLMIGIQLTDEKKVPEVLALLRENGLLALSAGHDVIRLLPPLVMTKVELQKGAELLEKIL
What are the official names of this protein?
Acetylornithine aminotransferase, ACOAT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF3_STRT1
Sequence: MSIRDEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVKGKKTGNFAKSDWMDIEKQRGISVTSSVMQFDYAGKRVNILDTPGHEDFSEDTYRTLMAVDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLEELEEVLGIASYPMNWPIGMGKAFEGLYDLYNERLELYKGNERFAKIEDGDTLFANNPFYEQTKEDIELLTEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLDTFLKFAPEPHGHKTVDGDEIDPLNKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLTRTGKGAKLSNVTQFMAESRENVENAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPELFMKVSAKNVMKQKSFHKGIEQLVQEGAIQLYTNYQTGEYMLGAVGQLQFEVFKHRMENEYNAEVVMTPMGKKTVRWIQPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDVTLEEKM
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLUP_STRGR
Sequence: VLGGGAIYGGGSRCSAAFNVTKGGARYFVTAGHCTNISANWSASSGGSVVGVREGTSFPTNDYGIVRYTDGSSPAGTVDLYNGSTQDISSAANAVVGQAIKKSGSTTKVTSGTVTAVNVTVNYGDGPVYNMGRTTACSAGGDSGGAHFAGSVALGIHSGSSGCSGTAGSAIHQPVTKALSAYGVTVYL
What is the function of this protein?
Preferentially cleaves peptide bonds on the carboxyl-terminal side of glutamate.
What are the official names of this protein?
Glutamyl endopeptidase 2, GLUSGP, Glutamic acid-specific protease, Glutamyl endopeptidase II, SGPE, Serine protease E, Streptogrisin-E.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
Protein: PSMA_HALDO
Sequence: YGEPIGVETLTK
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.
What are the official names of this protein?
Proteasome subunit alpha, Multicatalytic endopeptidase complex subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSXC_SALAR
Sequence: MLKLFSAFRKDKIWDFDGGIHPPEMKTQSNGTPLRQIPLAPRFVIPLKQHIGAEGELCVSVGDRVLRGQALTHGRGKMLPVHAPTSGTVIAVAPHSTAHPSALAELSVIIDADGEDRWIEREGWSDYRAHSREALIERIHQYGVAGLGGAGFPTGVKLQGGIDKITTLIINAAECEPYITADDRLMQDCAAQIVEGIRILAYILQPREVLIGIEDNKPQAISMLRAVLADAHDISLRVIPTKYPSGGAKQLTQILTGKQVPHGGRSSDIGVLMQNVGTAYAVKRAVVDGEPITERVVTLTGEAVSRPGNIWARLGTPVRHLLNNAGFCPSADQMVIMGGPLMGFTLPWLDVPVVKITNCLLAPSATEMGAPQEETSCIRCSACADACPADLLPQQLYWFSKGQQHDKATAHHIADCIECGACAWVCPSNIPLVQYFRQEKAEINAIRLEEKRAAEAKARFEARQARLEREKAARLARHKSAAVQPAAKDQDAIAAALARVKEKQAQATQPVIIQAGSLPDNSAAIAAREARKAQARAKQAGHPMADSATSGDDPRKAAVEAAVARAKARKQEQQAISEAAEPVDPRKAAVEAAIARAKARKQEQQAVSEAAEPVDPRKAAVEAAIARAKARKQEQQAVSVPVEPVDPRKAAVAAAIARVQAKKAAQQQVVNEE
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit C, Rsx electron transport complex subunit C.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: YL289_MIMIV
Sequence: MTQYISKYSPIDFGEYGYDKSFPYCYNGTCKNFSKLMWLVINEKSNPRIDGHKKIVKHLKKNKRKINAQNEHGWTALMIASILSNDWSSIKTVKLLLKKGADPNIENYNYSQTVLKLAASNVKYASNIKTIKLLIHYGADINHKNLLGVSVLHYCYIDYYTKSDNLEVIKLLLSYGMDINSVTNQGNTLLYIVSKVSQNNNSTETVKFLLENNADPNIPNNKGTTALMVASKYSNSTSNLATVKLLLDYEANINFMNKYNETALSKVVSNFYESNYNKNNFMTLKFLIQKGAIDIPIGIDKLSILMVAVIRTYCSENSDNFTKLIELLLKHFNPNIQCSNGKTVLHYLCNKQVCNFPYVDVINLLLKAGINPNIKDNQGKTALILACDNYCFLKNKEAVRLLCKVSTINTIDNTGQSALDYFLNKYKEKYTNILTIILKYGAYCVNKNNINKIKILKCFDYLNKNNKINKIHEKICDQIKLKAIKHQIRPTSLRMKIISLNWYSRSYQTDKIISWNNLDAIDYLGAIDIDDLRYKISDCTKYID
What are the official names of this protein?
Putative ankyrin repeat protein L289.
Protein: PRIO_CERAT
Sequence: MLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHNQWHKPSKPKTSMKHMAGAAAAGAVVGGLGGYMLGSAMSRPLIHFGNEYEDRYYRENMYRYPNQVYYRPVDQYSNQNNFVHDCVNITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYEKESQAYYQRGSSMVLFSSPPVILLISFLIFLIVG
What is the function of this protein?
Its primary physiological function is unclear.  Has cytoprotective activity against internal or environmental stresses.  May play a role in neuronal development and synaptic plasticity.  May be required for neuronal myelin sheath maintenance.  May play a role in iron uptake and iron homeostasis.  Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).  Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts.  Also provides Cu(2+) or Zn(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains (By similarity).
What are the official names of this protein?
Major prion protein, PrP, PrP27-30, PrP33-35C.
What is the protein family that this protein belongs to?
Belongs to the prion family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Golgi apparatus. Note=Targeted to lipid rafts via association with the heparan sulfate chains of GPC1. Colocates, in the presence of Cu(2+), to vesicles in para- and perinuclear regions, where both proteins undergo internalization. Heparin displaces PRNP from lipid rafts and promotes endocytosis.
Protein: RISB_STRGG
Sequence: MSGKGAPELSVRNCGDLRVAVIAAQWHEKVMDGLVDGALRALHELGIDEPTLLRVPGSFELPVVAKVLAGRGYDAIVALGVVIRGGTPHFEYVSQGVTLGLTQVTVDTGVPVGFGVLTCDTEEQALDRAGLEGSNEDKGHEAVTAAVATAATLRTVSEPWR
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: PYRB_XYLFT
Sequence: MNLKAITLMQFDSNGRLRHLLTLEGLSRHTLLQLLDCAAQNCALGVDPMGKRNVLAGMAVCTLFFEPSTRTRHSFHLAAQRLGADVLNFDASMSSTSKGESACDTLKNLEAMGVRGFIVRHPEEIVIAQLAAVVGEGTVLINAGAGRSTHPTQGLLDMLTLCQAKGNDFSKLKLLFVGDIKHSRVARSNLHALRTLGAGQIRVCGPTALLPHDGLLSGCVVSQDFDAMLEGVDVLMMLRLQRERMEEGLVPSLEHYHANYGLTAARLARAAPDAVVLHPGPINRGVEITDEVADGPQSWILRQASNGVMVRMAVLETLLG
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: KTHY_ASFP4
Sequence: MRGILIAIEGVNRVGKSTQAMRLKKALECMDYNAVCIRFPNPDTTTGDLILQVLNKMIEMSSEQLHKLFTKHCSEFVAEIAALLKLNFIVIVDRYIWSGLAYAQADGITIETKNIFKPDYTFFLSSKKPLNEKPLTLQRLFETKEKQETIFTNFTIIMNDVPKNRLCIIPATLNKEIIHTMILTKTIKVFDNNSCLNYIKMYDDKYLNVQELNLFDFEWQKCIEDNNDKEEYDDDDFII
What is the function of this protein?
Catalyzes the conversion of dTMP to dTDP.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: NTPPA_CLOD6
Sequence: MNIILASASPRRKEILENTNVRFDIIKNEIDEIILEGETPKHLVMRLAFEKSMSVASEHNEDVVIGADTVVVLDNAILGKPKDESCARDMLKRLSGREHQVITGISLINLCEDKKVIDYVISNVKFKTLSEQDIEDYLKTNESFDKAGAYGIQGYGALLVEEIRGDYFNIVGLPISRLGDLLKKYFSINLFYGV
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPC7_SCHPO
Sequence: MRRGARGSTNLGGMTWQEVLEFNANSTPTKLYPDRDIPLQRSIRPEELLELRFYKEIRTSFLDESAFYIRRNPISVVQRNEDGLVRYSDRNKPKRKNDNLSLSDLDLDPKFFPEELRKTLGAASATGRKRARRKLDMKTFIDFTIKAQDLKDESSEAAHPNIEEEPDEGLEEEDEDFGDDDDNDYGENYFDNGEGDDYDDYDGDEGAIYE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
What are the official names of this protein?
DNA-directed RNA polymerase III subunit rpc31, RNA polymerase III subunit C31, DNA-directed RNA polymerase III 31 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RPC7 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SYI_LISMO
Sequence: MEYKDTLLMPKTDFPMRGNLPNKEPEWQAKWEEEKLYEKIQEKNAGRPTYILHDGPPYANGELHMGHALNKTIKDIIVRYKSMAGFSSPYVPGWDTHGLPIETAIAKKGVKRKEMSIAEFRKLCAEYAMKQVDGQRTGFKRLGINGDWENPYITLLPEYEAEQIKVFGEMAKKGYIYKGKKPVYWSPSSESALAEAEIEYQDKTSASIFVAFKVTDGKGVLDEGTNIVIWTTTPWTIPANMGITVNPDLDYVVIESAGEKYVVAEALLPSLREKLGFEDATVVKTVRGSELDRVVTKHPFYDRDSLVMNGEHATAEAGTGAVHTAPGHGEDDFLIGKKYDLEILAPLDDRGVFTEEAPGFEGVFYDTANKMVTEKLEEVGALLKMEFITHSYPHDWRTKKPVIFRATAQWFASIDAFRDDLLAAVKGVNWTPAWGETRLFNMVRDRGDWVISRQRAWGVPLPIFYAENGEAIITDETINHISELFREHGSNVWFERDVKDLLPAGFTHPGSPNGEFTKETDIMDVWFDSGSSHQAVLNARPELSRPADLYMEGSDQYRGWFNSSLTTAVAITGEAPYRNVLSHGFALDGEGRKMSKSLGNTLLPGKVIKQLGADIVRLWVASVDYQADVRVSDEILKQVSEVYRKIRNTMRFLLGNINDFNPTTNTVSYENLREVDKYMLIKLNDLVKNVKDSYEAFEFSTIYHQINNFCTVELSQFYMDFAKDVVYIEAADSHDRRAMQTVFYEAVVTLTKLLAPILPHTTEEVWNSLIGEGAESIHLQDLPDVKVLANSEEITAKWDAFMQIRDNVQKALEFARNEKLIGKSMLAKVTLYVDGEAKTLFDSLEGDFAQLFIVSDFELVEGLENAPESAFKSNQVAVQITVAEGETCERCRVVKKDVGVNPKHPTLCGRCADIVVKHYEA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPRK1_OCEIH
Sequence: MVAVVRTQDLLDNFNLTLVSGEDGIQREIITSDISRPGIEMTGYFRYYPKERLQLIGKTEMAYFLDLSSEQRRDRAERLCTDITPGIVVSRGMDIPEELKEASEKSGVPILQSPRKTTRVISRLTNYLESKFAPFTAIHGVLVDIYGVGVLIIGQSGVGKSETALELVKRGHRLVADDNVEIRQEDYDSLIGNAPPLIEHLLEIRGLGIINVMTLFGAGSVRSKKRISLVINLENWDEKKQYDRLGLDEDMMKVMDVHLPKATVPVRPGRNLAVIIEVAAMNFRLKRMGVNTAEEFSERLSTMIEKGELE
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).  The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc. ) in the growth medium.  Also phosphorylates/dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue.  Therefore, by controlling the phosphorylation state of HPr and crh, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity).
What are the official names of this protein?
HPr kinase/phosphorylase 1, HPrK/P 1, HPr(Ser) kinase/phosphorylase 1.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: RS11_CLOBL
Sequence: MAAGMKGKRSRRRKERKNVEHGCAHIKSTFNNSIVTITDSVGNTLSWASAGGLGFRGSRKSTPFAAQMAAETAAKVAMEHGLKSIEVYVKGPGSGREAAIRSLQAAGLEVTLIKDVTPIPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: ELMD1_BOVIN
Sequence: MKHFLRMLIQVCLFFYCKFLWRCLKFVMRKLTGRCELQRICYNTKPGASRTMKIETSLRDSKSKLLQTSVSVHPDAIEKTIDDIMELKKINPDINPQLGISLQACLLQIVGYRNLIADVEKLRRESYDSDNPQHEEMLLKLWKFLKPNTPLESRISKQWCEIGFQGDDPKTDFRGMGLLGLYNLQYFAERDAAAAQQVLSDSLHPKCSKFSKAEWEKKRMDKAIGYSFAIVGINITDLAYNLLVSGALKTHFYNIAPEAPTLSHFQQTFCYLMHEFHKFWIEEDPMDIMEFNRVREKFRKRIIKQLQNPDMALCPHFAASEGLINM
What is the function of this protein?
Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family.
What are the official names of this protein?
ELMO domain-containing protein 1.
Protein: Y1232_BACC0
Sequence: MVHMHITAWALGLILFFVAYSLYSAGRKGKGVHMGLRLMYIIIIVTGFMLYMGIMKTATSNMHMWYGLKMIAGILVIGGMEMVLVKMSKNKATGAVWGLFIVALVAVFYLGLKLPIGWQVF
What are the official names of this protein?
UPF0344 protein BCAH820_1232.
What is the protein family that this protein belongs to?
Belongs to the UPF0344 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YGDD_ECO57
Sequence: MTSRFMLIFAAISGFIFVALGAFGAHVLSKTMGAVEMGWIQTGLEYQAFHTLAILGLAVAMQRRISIWFYWSSVFLALGTVLFSGSLYCLALSHLRLWAFVTPVGGVSFLAGWALMLVGAIRLKRKGVSHE
What are the official names of this protein?
UPF0382 inner membrane protein YgdD.
What is the protein family that this protein belongs to?
Belongs to the UPF0382 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL34_SACS2
Sequence: MPRPALRSRSLRRVYVKLPSGKTVIHYERKRNDIAICAICKKPLHGVKTNFLHKYSKSEKRPERPFGGYLCSSCLTQLIKATVRQQLQ
What are the official names of this protein?
50S ribosomal protein L34e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL34 family.
Protein: RL16_BRUO2
Sequence: MMQPKRTKFRKQFKGRIHGNSKGGTDLNFGAFGLKALEPERVTARQIEAARRAITRHMKRAGRVWIRIFPDLPVTSKPTEVRMGKGKGSVDYWACRVAPGRVMFELDGVPEDVAREALRLGAAKLPIKTRFIQRIAE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: MRAY_CHLSY
Sequence: MSVLRAVLVQDMARALLLAAAAFVLTLIIGGWWVRFARRHKLGKRIRPDGPQSHLVKVGTPTMGGIMIVSTVLILTILFNLVDRWSMLLPLGVMVSFAVLGAIDDWLSLTGSRSKTHGFTVRFKFWIMMAVAFVASLALYLPQPYGLEHEGLVQIPFVGEVNIGLWFIPIAVLIIVFISNAVNITDGLDSLAGWNLTLAFGAYGVITFLAEPRLTNLMAFCFTVVGACAAFLWYNAYPAQVFMGDLGALALGATLAVVALQSQQWLLLPVIGIVFVVEALSTMIQTGYFKWTKWRYGEGRRIFKMAPLHHHFELLGWSQPQVTQRFVLIGTVAAMVGISLALIFGPPATGLQVDQPGIIVIEGDGSR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VIRB3_BARQU
Sequence: MNEDTLFLACTRPATFAGVTMEGMALNVMATSILFILTSNFTMIGLGIGLHFVLREVTKYDHNQFRVLFAWLNTRGKQKNLTRWGGGSTSPLRLIRTYKELNR
What is the function of this protein?
Component of the type IV secretion system VirB/VirD4 which could be a major virulence determinant for subversion of human endothelial cell (HEC) function.  VirB3 may play a role in stabilization of pilus structure.
What are the official names of this protein?
Type IV secretion system protein virB3.
What is the protein family that this protein belongs to?
Belongs to the virB3 family.
What are the subcellular locations of this protein?
Cell outer membrane; Single-pass membrane protein.
Protein: Y032_CLOBH
Sequence: MARGGFPNMGGANMNNLMKQAQKLQQDMEKMQGEMEKKEFSATVGGGAVTAVANGKKQIVDIKIEPEVVDEDDIEMLEDLIMSACNEALKKAEEDTSSEVKRLTGGMNLPGMF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein CBO0032/CLC_0052.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.