PharMolix/UniProtQA huggingface dataset:
Protein: SECE_STAAC
Sequence: MAKKESFFKGVKSEMEKTSWPTKEELFKYTVIVVSTVIFFLVFFYALDLGITALKNLLFR
What is the function of this protein?
Essential subunit of the Sec protein translocation channel SecYEG.  Clamps together the 2 halves of SecY.  May contact the channel plug during translocation.
What are the official names of this protein?
Protein translocase subunit SecE.
What is the protein family that this protein belongs to?
Belongs to the SecE/SEC61-gamma family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PGK_ENTFA
Sequence: MAKKTIKDVDLKDKKVLVRVDFNVPLKDGVITNDNRIVAALPTIKYVIENGGKAILFSHLGRVKTEEDKAGKSLKPVAERLSELLGQPVTFVPETRGKELEDAVNNMKDGDVLVFENTRFEDVDGKKESGNDAELGKYWASLGDVFVNDAFGTAHRAHASNVGIASTGIPTVAGFLMEKEIKFIGEAVENPKRPFVAILGGAKVSDKIAVIENLIEKADKILIGGGMAYTFMKAQGYSVGLSLLEEDKVDLAKSLMEKAGDKLVLPVDTVVSKEFSNDAPFHTVPSTEIPDDEEGLDIGEKTIELFANELQGAKTVVWNGPMGVFEMSNFAKGTIGVCEAIANLEDATTIIGGGDSAAAAIQLGYENKFSHISTGGGASLELLEGKTLPGLASINDK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIMT_VIBCH
Sequence: MANPKADRLIQFLTEQGITSPQVLAAIHALPREFFVAPAMMHQAYDNNALPIGQGQTISQPYIVAKMTELLALTPETKVLEIGTGSGYQTAVLAKLVNHVFTVERIKTLQWDAKRRLKQLDIYNVSTKHGDGWQGWPARGPFDAILVTAAAAKVPQSLLDQLAEGGRMVIPVGEDEQYLYKIVRQGGQFISERVEAVRFVPLVAGDLA
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14Z_MYCS2
Sequence: MAKKALVHKANKKPKFAVRAYTRCNKCGRPHSVYRKFGLCRICLREMAHAGELPGVQKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: FXRD2_DANRE
Sequence: MSVIQLVFRLLCVLDLLLAVSASGLHGRNRTLSHEYCVLGAGPAGLQMGYFLSRSQRDYIILERNAGPGSFFNIYPRHRKLISINKIYTGRRNKEFNLRHDWNSLLSDRPDLLFQRISRKLYPSADDFPHYLSLFEKELGLKVKYGTDVGRIKASDFNGHQGYVLTDQNGVNYQCRVLLVSTGLWVPQEVDFRGSDLVEGYESIPTDPEEFKDQAVLILGKGNSAFETAQSILGRASRIHLYSPSPVRLAWQTHYVGDLRAVNNELLDTYQLKSLDGLVEGRLEDIAIVRRAKDRGKRRAAKKRNSTSTKRNEPLYLTLTELLDDQNDTNISNVTGQNLPGYHTDNFSLRQPYDRVIRCLGFRFNFSIFDGSARPPQSSGARGRLPGVTAWYEGRGTPNMFVLGIAAHSRDYRMSAGGFIHGFRYTVRAVHKILEQRYHNIAWPTTNIPISQLQSWILRRVNEASGTYQMFGVLGDIILLQGSHCEYLEEFPLQALPQLSALSGRSISDHGLLVLVMQYGLNHTDTLGPGRAESEWTKAWKSNFLHPVLYYYKTLPTDKDMRQRPVGWPLPRPEAVHHMVEDFLTEWDQPISHSQPLRRFLEHCLKTDLRAFYAESCFLLSLTSRNPPLFCRQGYLRKQGIMGNRHLWQHAREAGLMEDAALSEDASVPEYLNHAGAAVISTVNFDL
What is the function of this protein?
Probable flavoprotein which may function in endoplasmic reticulum associated degradation (ERAD).  May bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation (By similarity).
What are the official names of this protein?
FAD-dependent oxidoreductase domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the FOXRED2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: TBX2A_XENLA
Sequence: MRDPAFPGAAMAYHPFHAPRAADFPMSAFLAAAQPSFFPALTLPPAALGKPLSDASLAGAAEAGLHLSALGHHHQAAHLRSLKSLEPEEEVEDDPKVNLEAKELWDQFHKIGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLSLPSLRMYEEQCKADRDGAESDASSCDPAPGRDSLHSPLSAEPSPLRLHRNNREEKFGADSDQELDRREIRSARSHSPVGHRSPPSSPRLEDRGKDKSTPEKKSDSPESRKDGSDSLFSSIRSLEKDKAESRRKEDSKSDPECGSLSKETFAPLMVQTDSPPHLSASHLQSLALSGLHGQQFFNPLNAGQPLFIHPGQFTMGPGAFSAMGMGHLLASMTGAGALDNGSLSSVQGATGAANPFPFHFSQHMLASQGIPMPAFGGLFPYPYTYMAAAAAAASAMPATSAATTMPRNPFLSSTRPRLRFNPYQIPVGIPPSTNLLTTGLPGSLNPGSESSKPGSSRESSPIPDTPVPKRSHSNSLSPKASMKDSINELQNIQRLVSGLESQREISPGRETPK
What is the function of this protein?
Transcription factor which acts as a transcriptional repressor (By similarity).  May also function as a transcriptional activator (By similarity).  Binds to the palindromic T site 5'-TTCACACCTAGGTGTGAA-3' DNA sequence, or a half-site, which are present in the regulatory region of several genes (By similarity).
What are the official names of this protein?
T-box transcription factor TBX2-A, T-box protein 2-A.
What are the subcellular locations of this protein?
Nucleus.
Protein: SRK2B_ARATH
Sequence: MDKYELVKDIGAGNFGVARLMRVKNSKELVAMKYIERGPKIDENVAREIINHRSLRHPNIIRFKEVVLTPTHIAIAMEYAAGGELFERICSAGRFSEDEARYFFQQLISGVSYCHAMQICHRDLKLENTLLDGSPAPRLKICDFGYSKSSLLHSMPKSTVGTPAYIAPEVLSRGEYDGKMADVWSCGVTLYVMLVGAYPFEDQEDPKNFKKTIQRIMAVKYKIPDYVHISQDCKHLLSRIFVTNSNKRITIGDIKKHPWFLKNLPRELTEIAQAAYFRKENPTFSLQSVEEIMKIVEEAKTPARVSRSIGAFGWGGGEDAEGKEEDAEEEVEEVEEEEDEEDEYDKTVKQVHASMGEVRVS
What are the official names of this protein?
Serine/threonine-protein kinase SRK2B, OST1-kinase-like 6, SNF1-related kinase 2.10, SnRK2.10.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: GARL_SALSV
Sequence: MNNAIFPNKFKAALAAQQVQIGCWSALASPITTEVLGLAGFDWLVLDGEHAPNDVTTLIPQLMALKGSASAPVVRVPTNEPVIIKRMLDIGFYNFLIPFVETQEEAARAVASTRYPPEGIRGVSVSHRANMFGTVPDYFAQSNKNITIIVQIESQLGVDNVDAIAATEGVDGIFVGPSDLAAALGHLGNASHPDVQQTIQHIFARAKAHGKPCGILAPVEADARRYLEWGATFVAVGSDLGAFRASTQKLADTFKK
What is the function of this protein?
Catalyzes the reversible retro-aldol cleavage of both 5-keto-4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde.
What are the official names of this protein?
5-keto-4-deoxy-D-glucarate aldolase, KDGluc aldolase, KDGlucA, 2-dehydro-3-deoxy-D-glucarate aldolase, 2-keto-3-deoxy-D-glucarate aldolase, 5-dehydro-4-deoxy-D-glucarate aldolase, Alpha-keto-beta-deoxy-D-glucarate aldolase.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily.
Protein: RL14_CHLT3
Sequence: MIQKETDLMVADNSGAKRVRCIHVLGGTGRRYATIGDMIVVSVKSAIPGGAVKKKDVSKAVVVRTKKEYRRKDGSYIRFDENAVVLLNTQGEPRGTRIFGPVARELRDKQYMKIISLAPEVI
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: Y2928_POLSJ
Sequence: MGAQWKAKGKAQAADARGKLFGRLAKDIMVAARGGADPASNSRLRLVVEQARKVSMPKDTLERAIKKGAGLTGEAVHFEHVMYEGFAPHQVPVMVECLTDNVKRTAPEMRVLFRKGHLGASGSVAWDFDHVGMIEAEPVVAGSDPEVAAIEAGAEDFEPGHEEGTTLFLTAPTDLDLVSRALPAQGFTVISAKLGYKPKNPIDPASLDPAHLEEVEAFLAAIDANDDVQNVFVGLAG
What are the official names of this protein?
Probable transcriptional regulatory protein Bpro_2928.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIF3M_NEOFI
Sequence: MPAPTTTLLIEGTFTELADEFAQYIDALRKNEGASLQSEIAPLIEPLRQQEQSEEEPDRKQRDEVLKKLVGAAAVLNAAPEKEIISAYNLLVHLVHQASNPDMFLSRICTYLAKPITTSPQFGPTLAISILSTIFNTLAPTDSSRFHVLLAIVAVIRQSGSSYAFEALKPQLAAQLPTWLSAWELDDEDAQKLHLAVADAAQASGDLELAQTHVVQALQTIPANESSSKEARDLAVRALTSALKSPGVFDFTSLTAADAIQALRSSDSTLFELLEIFTADTLDAYEDFIAATPLETISGGVLADGAEALQTKMRLLTLASLAASTPSRSLPYATIASALRVPVEDVEKWVIDTIRAGLVEGKLSQLRSEFLVHRATYRVFGEKQWAEVQGRLMVWRRSLESVLGVLRTERERYIRESMQAAAEETGQGKSGDKGAKGGDRRRNPQQQQQSQPSQPQQAREVELVGGAE
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit M, eIF3m.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit M family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAAH1_MOUSE
Sequence: MVLSEVWTALSGLSGVCLACSLLSAAVVLRWTRSQTARGAVTRARQKQRAGLETMDKAVQRFRLQNPDLDSEALLALPLLQLVQKLQSGELSPEAVLFTYLGKAWEVNKGTNCVTSYLTDCETQLSQAPRQGLLYGVPVSLKECFSYKGHASTLGLSLNEGVTSESDCVVVQVLKLQGAVPFVHTNVPQSMLSYDCSNPLFGQTMNPWKPSKSPGGSSGGEGALIGSGGSPLGLGTDIGGSIRFPSAFCGICGLKPTGNRLSKSGLKSCVYGQTAVQLSVGPMARDVDSLALCMKALLCEDLFRLDSTIPPLPFREEIYRSSRPLRVGYYETDNYTMPTPAMRRAVMETKQSLEAAGHTLVPFLPNNIPYALEVLSAGGLFSDGGCSFLQNFKGDFVDPCLGDLVLVLKLPRWFKKLLSFLLKPLFPRLAAFLNSMCPRSAEKLWELQHEIEMYRQSVIAQWKAMNLDVVLTPMLGPALDLNTPGRATGAISYTVLYNCLDFPAGVVPVTTVTAEDDAQMEHYKGYFGDMWDNILKKGMKKGIGLPVAVQCVALPWQEELCLRFMREVERLMTPEKRPS
What is the function of this protein?
Catalyzes the hydrolysis of endogenous amidated lipids like the endocannabinoid anandamide (N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine), as well as other fatty amides such as the taurine-conjugated fatty acids (a structural class of central nervous system (CNS) metabolites), to their corresponding fatty acids, thereby regulating the signaling functions of these molecules (PubMed:15533037, PubMed:32271712).  FAAH cooperates with PM20D1 in the hydrolysis of amino acid-conjugated fatty acids such as N-fatty acyl glycine and N-fatty acyl-L-serine, thereby acting as a physiological regulator of specific subsets of intracellular, but not of extracellular, N-fatty acyl amino acids (PubMed:32271712).  It can also catalyze the hydrolysis of the endocannabinoid 2-arachidonoylglycerol (2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol) (By similarity).
What are the official names of this protein?
Fatty-acid amide hydrolase 1, Anandamide amidohydrolase 1, Fatty acid ester hydrolase, Oleamide hydrolase 1.
What is the protein family that this protein belongs to?
Belongs to the amidase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Golgi apparatus membrane; Single-pass membrane protein. Note=Seems to be associated with the endoplasmic reticulum and/or Golgi apparatus.
Protein: PEX12_BOVIN
Sequence: MAEHGAHITTASVVDDQPSIFEVVAQDSLMSAVRPALQHVVKVLAESNPAHFGFFWRWFDEIFTLLDLLLQQHYLSKTSASFSENFYGLKRIVMGDQHKLQRLANAGLPKQQFMKSIMFLVLLPYLKVKLEKLVSSLREEDEYSIHPPSSRWKRFYRAFLAAYPFVNMAWEGWFLVQQLRYILGKAQHHSPLLRLAGVRLGRLTVQDIQALEHKPAEASMMQLPAGSIGEKIKSALKKAVGGVALSLSTGLSVGVFFLQFLEWWYSSENQETIKSLTALPTPPPPVHLDYNSDSPLLPKMKTVCPLCRKNRVNDTVLATSGYVFCYRCVFHYVRSHQACPITGYPTEVQHLIKLYSPEN
What is the function of this protein?
Component of a retrotranslocation channel required for peroxisome organization by mediating export of the PEX5 receptor from peroxisomes to the cytosol, thereby promoting PEX5 recycling (By similarity).  The retrotranslocation channel is composed of PEX2, PEX10 and PEX12; each subunit contributing transmembrane segments that coassemble into an open channel that specifically allows the passage of PEX5 through the peroxisomal membrane (By similarity).  PEX12 also regulates PEX5 recycling by activating the E3 ubiquitin-protein ligase activity of PEX10 (By similarity).  When PEX5 recycling is compromised, PEX12 stimulates PEX10-mediated polyubiquitination of PEX5, leading to its subsequent degradation (By similarity).
What are the official names of this protein?
Peroxisome assembly protein 12, Peroxin-12.
What is the protein family that this protein belongs to?
Belongs to the pex2/pex10/pex12 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Multi-pass membrane protein.
Protein: Y4136_BACC2
Sequence: MVHMHITAWALGLILFFVAYSLYSAGRKGKGVHMGLRLMYIIIIVTGFMLYMSIVKTATGSMHMWYGLKMLTGILVIGGMEMVLVKMSKNKPTGAVWGLFIVALVAVFYLGLKLPIGWKVF
What are the official names of this protein?
UPF0344 protein BCG9842_B4136.
What is the protein family that this protein belongs to?
Belongs to the UPF0344 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ARGJ_LISMO
Sequence: MELIKGNIASPKGFYADGKHAGLKRKRNDIGWIYSEVPANAAAVYTMNQMQAAPIFVTKDSFQSNAKLQAIIVNSGNANACTGNQGMLDALAMRAQTAEKLEIPLDSVAVASTGIIGDMLPMDKINAGIEMLEKQTGNAADFEEAILTTDTFQKQISFQTEIGGRKVTMSGVAKGSGMIHPNMATMLAFITTDAAIPAELLQKLLKIKVDKTFNQITVDGDTSTNDMVVVMANGCAENPMLQEGTADFAKFADMFQAVTEHLAKSIARDGEGATKLIEVQVNGATKTEDARMIAKKIVSSSLVKTAAFGGDGNWGRIICAIGYSGGRFAPDNITIKIGGIEILNHSSQTIYNQQALDAYLEEEHIIIEVDLHIGLESGTAWGCDLSYEYVKINACYRT
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA66E_SHEEP
Sequence: RDSNVTILPLRNMKD
What are the official names of this protein?
Pregnancy-associated glycoprotein 66e, ovPAG 66e.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
Protein: COR12_PAPSO
Sequence: MESNGVPMITLSSGIRMPALGMGTVETMEKGTEREKLAFLNAIEVGYRHFDTAAAYQSEECLGEAIAEALQLGLIKSRDELFITSKLWCADAHADLVLPALQNSLRNLKLEYLDLYLIHHPVSLKPGKLVNEIPKDHILPMDYKSVWAAMEECQTLGFTRAIGVSNFSCKKLQELMATAKIPPVVNQVEMSPTLHQKNLREYCKANNIMITAHSVLGAIGAPWGSNAVMDSKVLHQIAVARGKSVAQVSMRWVYQQGASLVVKSFNEARMKENLKIFDSELTAEDMEKISEIPQSRTSSADFLLSPTGPFKTEEEFWDEKD
What is the function of this protein?
Reduces codeinone to codeine in the penultimate step in morphine biosynthesis.  Can use morphinone, hydrocodone and hydromorphone as substrate during reductive reaction with NADPH as cofactor, and morphine and dihydrocodeine as substrate during oxidative reaction with NADP as cofactor.
What are the official names of this protein?
NADPH-dependent codeinone reductase 1-2.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Note=Present in the cytosolic part of laticifer cells that secrete latex.
Protein: GLYA_FLAJ1
Sequence: MQRDEQIFDLIQEEKDRQIHGLELIASENFVSDEVMEAAGSVLTNKYAEGYPGKRYYGGCEVVDVIEQIAIDRAKELFGAEYANVQPHSGSQANTAVYHACLNPGDTILGFDLSHGGHLTHGSPVNFSGRLYRPVFYGVDAETGRLDYDKIQEIATKEQPKLIIAGASAYSRDMDFARFRQIADSVGAILFADISHPAGLIAKGLLSDPIPHCHIVSTTTHKTLRGPRGGLILMGKDFPNPQGLTTPKGEIRMMSSLLDLAVFPGNQGGPLMHIIAAKAVAFGEALKDEFFTYAMQLQKNANAMADAFVKRGYNIISGGTDNHMMLIDLRNKNISGKEAENALVKAEITVNKNMVPFDDKSPFITSGIRVGTAAITTRGLVEKDMETIVALIDKVLTNHTNEDVIEEVAEEVNELMSERPIFAY
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIGM_MACFA
Sequence: MGSTKHWGEWLLNLKLAPAGVFGVAFLARVALVFYGVFQDRTLHVRYTDIDYQVFTDAARFVAEGRSPYLRATYRYTPLLGWLLTPNIYLSELFGKFLFISCDLLTAFLLYRLLLLKGLARRQACGYCVFWLLNPLPMAVSSRGNADSIVASLVLMVLYLIRKRVVACAAVFYGFAVHMKIYPVTYILPITLHLLPDRDNDKSLRQSRYTFQAHLYELLKRLCDRAVLLFVAVAGLTFFALSFGFYYEYGWEFLEHTYFYHLTRRDIRHNFSPYFYMLYLTAESKWSFSLGIAAFLPQFILLSAVSFAYYRDLVFCCFLHTSIFVTFNKVCTSQYFLWYLCLLPLVMPLVRMTWKRAVVLLMLWFIGQALWLAPAYVLEFQGKNTFLFIWLAGLFFLLINSSILIQIISHYKEEPLTERIKYD
What is the function of this protein?
Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.  Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly (By similarity).
What are the official names of this protein?
GPI mannosyltransferase 1, GPI mannosyltransferase I, GPI-MT-I, Phosphatidylinositol-glycan biosynthesis class M protein, PIG-M.
What is the protein family that this protein belongs to?
Belongs to the PIGM family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SYT_ENT38
Sequence: MPVITLPDGSQRQFDRAVSPMDVALDIGPGLAKATIAGRVNGELVDASDLIENDAQLSIITAKDAEGIEIIRHSCAHLLGHAIKQLWPNTKMAIGPVIDNGFYYDVDLDHTLTQEDIDALEKRMHELAETNYDVIKKNVSWHEARETFVKRGENYKVSILDENISHDDKPGLYHHEEYVDMCRGPHVPNMRFCHHFKLMKIAGAYWRGDSNNKMLQRIYGTAWADKKALNAYLVRLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELETFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGALHGLMRVRGFTQDDAHIFCTEGQVRDEVNACIRMVYDMYSTFGFEKIVVKLSTRPEKRIGSDETWDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPQRLSASYVGEDNERQIPVMIHRAILGSIERFIGILTEEFAGFFPTWLAPVQVVVMNITDSQADYVKELTQKLQNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRGKDLGSLDVNEVIEKLRLEIRSRSLQQLEV
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM240_MOUSE
Sequence: MSMSANTMIFMILGASIVMAIACLMDMNALLDRFHNYILPHLRGEDRVCHCNCGRHHIHYVIPYDGDQSVVDASENYFVTDNVTKQEIDLMLGLLLGFCISWFLVWMDGVLHCAVRAWRAGRRYDGSWTWLPKLCSLRELGRRPHRPFEEPTGNMVHVKQKLYHNGHPSPRHL
What are the official names of this protein?
Transmembrane protein 240.
What are the subcellular locations of this protein?
Synapse. Cell membrane; Multi-pass membrane protein.
Protein: RL24_STAAC
Sequence: MHIKKGDNVKVIAGKDKGKEGKVIATLPKKDRVVVEGVNIMKKHQKPTQLNPEGGILETEAAIHVSNVQLLDPKTNEPTRVGYKFVDGKKVRIAKKSGEEIKSNN
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: YIHY_SALCH
Sequence: MLKTVHQKAGRHTRPVRAWLKLLWQRIDEDNMTTLAGNLAYVSLLSLVPLIAVVFALFAAFPMFSDVSIQLRHFIFANFMPATGDVIQRYIEQFVANSNKMTAVGACGLIVTALLLMYAIDSALNTIWRSKRTRPKVYSFAVYWMILTLGPLLAGASLAISSYLLSLRWASDLNTVIDNVLRILPLLLSWISFWLLYSIVPTTRVPNRDALVGAFVAALLFEAGKKGFALYITMFPSYQLIYGVLAVIPILFVWVYWTWCIVLLGAEITVTLGEYRKLKQAAEQEEADQP
What are the official names of this protein?
UPF0761 membrane protein YihY.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: 2ABA_PIG
Sequence: DDDVAEADIISTVEFNHSGELLATGDKGGRVVIFQQEQENKIQSHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQFLLSTNDKTIKLWKISERDKRPEGYNLKEEDGRYRDPTTVTTLRVPVFRPMDLMVEASPRRIFANAHTYHINSISINSDYETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPNSCNTFVYSSSKGTIRLCDMRASALCDRHSKLFEEPEDPSNRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKIWDLNMENRPVETYQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSVVMTGSYNNFFRMFDRNTKRDITLEASRENNKPRTVLKPRKVCASGKRKKDEISVDSLDFNKKILHTAWHPKENIIAVATTNNLYIFQDKVN
What is the function of this protein?
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.  Essential for serine/threonine-protein phosphatase 2A-mediated dephosphorylation of WEE1, preventing its ubiquitin-mediated proteolysis, increasing WEE1 protein levels, and promoting the G2/M checkpoint.
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform, PP2A subunit B isoform B55-alpha, PP2A subunit B isoform PR55-alpha, PP2A subunit B isoform R2-alpha, PP2A subunit B isoform alpha.
What is the protein family that this protein belongs to?
Belongs to the phosphatase 2A regulatory subunit B family.
Protein: CUTA_PYRHO
Sequence: MIIVYTTFPDWESAEKVVKTLLKERLIACANLREHRAFYWWEGKIEEDKEVGAILKTREDLWEELKERIKELHPYDVPAIIRIDVDDVNEDYLKWLIEETKK
What is the function of this protein?
Involved in resistance toward heavy metals.
What are the official names of this protein?
Divalent-cation tolerance protein CutA.
What is the protein family that this protein belongs to?
Belongs to the CutA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_STRM5
Sequence: MTSRLEKFYKEEVVPALMKQFGYTNPMEVPKLVKVTLNMGVGEAATNKKILENAVGDMTKISGQKPVVTKSRISVASFKIRDGWPIGCKTTLRRHKMYEFLDRLINISLPRVRDFRGVSGRSFDGRGNFNMGVKEQIIFPEIDFDAVDAIRGMDIAITTTAKTDAEAKALLAAFKFPFRN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: SYE1_RICB8
Sequence: MTKVITRFAPSPTGMLHVGNIRAALLNWLYAKKHDGQFILRFDDTDLERSKQEYKDAIRADLKFLNLNWDQTFNQLSRLSRYDEIKKLLLDKKRLYACYETPEELELKRKFQLSKGLPPIYDRAALNLTEDQIQKYIEQGRKPHYRFLVNHEPITWHDMIKGEVKYEGKALSDPIVIRADGSMTYMLCSVIDDVDYEITHIIRGEDHVSNTAIQIQMFEALDKYPPTFGHLSLIINKDEKISKRVGGFEIATLREEVGLEAMAIASFFSLLGSSAQIIPHKKMDELVKHFEISSFSKSPTIYQPEDLERLNHKLLISLEFNEVKDRLKEIDAEYIDENFWLSVRPNLKKLFDAKDWWEICHKTPNIQDLNLDKEYLKQAAELLPEEEITTETWGIWTKKLAAITNRKGKELFLPLRLALTGKESGPEISKVLPLIKREEIVKRLT
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 1, Glutamyl-tRNA synthetase 1, GluRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSGA_SHIF8
Sequence: MTNSNRIKLTWISFLSYALTGALVIVTGMVMGNIADYFNLPVSSMSNTFTFLNAGILISIFLNAWLMEIVPLKTQLRFGFLLMVLAVAGLMFSHSLALFSTAMFILGVVSGITMSIGTFLITQMYEGRQRGSRLLFTDSFFSMAGMIFPMIAAFLLARSIEWYWVYACIGLVYVAIFILTFGCEFPALGKRAPKTDAPVEKEKWGIGVLFLSVAALCYILGQLGFISWVPEYAKGLGMSLNDAGTLVSNFWMSYMVGMWAFSFILRFFDLQRILTVLAGLAAILMYVFNTGTPAHMAWSILALGFFSSAIYTTIITLGSQQTKVPSPKLVNFVLTCGTIGTMLTFVVTGPIVEHSGPQAALLTANGLYAVVFVMCFLLGFVSRHRQHNTLTSH
What are the official names of this protein?
Protein TsgA.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TsgA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.