PharMolix/UniProtQA huggingface dataset:
Protein: MURD_RIPO1
Sequence: MATAYIIGLGRSGIAAARLLKIQGWEVILSDRAHSPNLEITQQELGQEGITVKLADHPSLIDSNLPNLIVVSPGVPWDVNFLQEARDRGIDVIGELELAWRSLQSSPWVGITGTNGKTTTTALVAAIFQASGLNAPSCGNIGYAACELALSQTKTKASSFDWIIAEVSSYQIESSRELAPKIGIWTTFTPDHLSRHKTLDNYYAIKASLLRRCELQIFNGDDPYLHQVGLHQWADAYWTTVKGKEHLLCDAAKGVYLQDNWIVAFGELIAPLNLFKMVGVHNQQNLLMAVGAARLAGIEKGAIAQAIATFKGVPHRLELITNIDGIDFINDSKATNYDAAEVGLVSVNASVILIAGGEAKEGDDRRWIEQIKAKVATVLLIGEAATAFAQRLQQSNYEAYEIVETMDNAVKRGLELAKKQQAKVVLLSPACASFDQYQSFEHRGDHFRQLCQALKE
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENP1_ENCIN
Sequence: MKLLGLLISAFGAINALKIKALYLSCDYELRPYNAVIDSQCMAFALNGSNIHEAIRYLNAMNIDKAYVLYWNDHDLHQNPMVLHKNGALAPFDRYTNTAKHVLCVEACSCPGPQSRPVVCPENNGASVSSPCPPCGQGNNTTVCDKVVVNPQPVKPLPAPCTPCAPCESSSSEKSESKECMTFPRICKKKCGPRHGRSPKKVEIVKSQKTYTFDIERYKRRGDVVVRVCSQDCKDKFEKFVLTKTGEIRKGKDKKCIPEPLPECLQCPKNLYKLKSGIEAKVCSEVCMYINSKCEIFVLIGDCDFYKVVMNERRRKQSSFHLKKIRGQKLRELIRQGLFGVEFSPLKC
What is the function of this protein?
Spore wall protein involved in the adhesion to host cells surface glycoaminoglycans (GAGs).  Microsporidian spore adherence is an integral part of activation and host cell infection.
What are the official names of this protein?
Spore wall and anchoring disk complex protein EnP1, Host cell adhesion protein EnP1.
What are the subcellular locations of this protein?
Spore wall. Spore, perispore. Note=Localizes also at the anchoring disk complex which consists of the polar sac and the anchoring disk, playing a crucial role in the rupture of the spore wall and the subsequent release of the polar tube following activation.
Protein: HPCA_MOUSE
Sequence: MGKQNSKLRPEMLQDLRENTEFSELELQEWYKGFLKDCPTGILNVDEFKKIYANFFPYGDASKFAEHVFRTFDTNSDGTIDFREFIIALSVTSRGRLEQKLMWAFSMYDLDGNGYISREEMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRLLQCDPSSASQF
What is the function of this protein?
Calcium-binding protein that may play a role in the regulation of voltage-dependent calcium channels.  May also play a role in cyclic-nucleotide-mediated signaling through the regulation of adenylate and guanylate cyclases.
What are the official names of this protein?
Neuron-specific calcium-binding protein hippocalcin.
What is the protein family that this protein belongs to?
Belongs to the recoverin family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Membrane; Peripheral membrane protein. Note=Association with membranes is calcium-dependent (By similarity). Enriched in the perinuclear region, probably at the trans Golgi network in response to calcium (By similarity).
Protein: CLPX_BACC0
Sequence: MFKFNDEKGQLKCSFCGKTQTQVRKLVAGPGVYICDECIELCTEIVQEELAKDEEVEFKDVPKPVEIREILDEYVIGQDNAKKALAVAVYNHYKRINSNSKIDDVELAKSNIALIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNILFICGGAFDGIEPIIKRRLGEKVIGFGSEKKNADVNEKHVLSHVLPEDLLRFGLIPEFIGRLPVIANLEPLDEDALVDILTKPKNALVKQFQKLLELDDVELEFEEGALIEIAKKAIERKTGARGLRSIIEGLMLEVMFELPSRKDIEKCILTKETVADNAAPKLVLQDGTVLDTKTSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: MTU1_DANRE
Sequence: MGVLRHVVCAMSGGVDSSVSALLLKRMGYHVTGVFMKNWDSQEEKGLCSSDRDCEDAYKVCKMLDIPFHEVSYVKEYWHEVFSNLLWEYERGRTPNPDIICNKHIKFKHFYQYAVNTLGADAMATGHYARTSQEDEEVFQQKLTEAPKSLFRDRFEIRKPVRLYQGADLLKDQTFFLSQISQDALRHTLFPLAGLTKGYVKKIAAEAGFQHVLKKKESMGICFIGKRDFENFILEYLEPRPGNFVSIEDGQIMGKHKGWFTLTLGQRARIGGRADAWFVVDKDVTTADVFVCPSTFHPALFRDTLQTDRFHWIAEEPPAELVHTQMMDCHFCFNNRMPLTPCTVTLNLDGSVWVMVKEPMRGMATGQFAVLYKGHECLGSGKIIRLGPTKFALQKDQSNTNCLHKDTNQQHPEPHS
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position.  ATP is required to activate the C2 atom of the wobble base.
What are the official names of this protein?
Mitochondrial tRNA-specific 2-thiouridylase 1.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: DC4L1_HUMAN
Sequence: MEAERLRLLEEEAKLKKVARMGFNASSMLRKSQLGFLNVTSYSRLANELRVSCMERKKVQIRSLDPSSLASDRFNFILASTNSDQLFVVNQVEVEGSKYGIISLRTLKIPSFHVYVLRNLYVPNRKVKSLCWASLNQLDSHVLLCFEGITDAPSCAVLLPASRFLSVHTRVNQPGMLCSFQIPEAWSCAWSLNTRAYHCFSAGLSQQVLLTSVATGHQQSFDTSSDVLAQQFASTAPLLFNGCRSGEIFAIDLRCRNRGKGWRATRLFHDSAVTSVQILQEEQCLMASDMTGKIKLWDLRATKCVRQYEGHVNESAYLPLHVHEEEGIVVAVGQDCYTRIWSLHDAHLLRTIPSPYSASEDDIPSVAFASRLGGIRGAAPGLLMAVRQDLYCFPFS
What are the official names of this protein?
DDB1- and CUL4-associated factor 4-like protein 1, WD repeat-containing protein 21B.
Protein: VP7_ROTW3
Sequence: MYGIEYTTILIFLTSITLLNYILKSITRIMDYIIYRFLLMVVILATIINAQNYGVNLPITGSMDTAYANSTQSEPFLTSTLCLYYPVEASNEIADTEWKDTLSQLFLTKGWPTGSVYFKEYADIAAFSVEPQLYCDYNLVLMKYDSTQKLDMSELADLILNEWLCNPMDITLYYYQQTDEANKWISMGSSCNVKVCPLNTQTLGIGCLITNPDTFETVATTEKLVITDVVDGVNHKLNVTTATCTIRNCKKLGPRENVAVIQVGGANILDITADPTTTPQTERMMRINWKKWWQCFYTVVDYVNQIIQTVSKRSRSLNSSAFYYRV
What is the function of this protein?
Calcium-binding protein that interacts with rotavirus cell receptors once the initial attachment by VP4 has been achieved.  Rotavirus attachment and entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors.  Following entry into the host cell, low intracellular or intravesicular Ca(2+) concentration probably causes the calcium-stabilized VP7 trimers to dissociate from the virion.  This step is probably necessary for the membrane-disrupting entry step and the release of VP4, which is locked onto the virion by VP7.
What are the official names of this protein?
Outer capsid glycoprotein VP7.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP7 family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum lumen. Note=The outer layer contains 780 copies of VP7, grouped as 260 trimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple-layered particles.
Protein: MIAB_RIPO1
Sequence: MTPKKMTHYQRHYHITTFGCQMNKADSERMAGILENMGFIWSEDPNQADLILYNTCTIRDNAEQKVYSYLGRQAKRKHENPDLTLIVAGCVAQQEGEQILRRVPELDLVMGPQHANRLEDLLQQVFDGNQVVATEPIHIIEDITKPRRDSTITAWVNVIYGCNERCSYCVVPNVRGVEQSRTPEAILAEMELLGKQGYKEVTLLGQNIDAYGRDLPGVTESGRHQHTLTDLLYTVHDVVGIERIRFATSHPRYFTERLIAACQELSKVCEHFHIPFQSGDNDILKAMKRGYTHEKYRQIIDKIRDYMPDASISADAIVGFPGETEEQFENTLKLVEDIGFDQLNTAAYSPRPGTPAALWDNQLSEEVKSDRLQRLNHLVAQKAAERSQRYLGRIEEVLVEDQNPKDSTQVMGRTRGNRLTFFKGDINQLKGRLIKVKITEVRAFSLTGEIV
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HDRB2_METMP
Sequence: MKYAFFLGCIMPNRYAGVESATRTVMEKLGVELVDMPGASCCPAPGVFGSFDQKTWLTLAARNLVIAEEMGTDIVTVCNGCYGSLYEAAHMLHENKEALAMVNEQLKEIGKEYKGTVHVRHFAELIYKEIGVDKIRENVVKPLAVNIGVHYGCHFLKPTAAKGLGNAEHPTMLDELVEATGAKSVDYKDKMMCCGAGGGVRAKELDLALSMTQEKIENMLAVGADATVNVCPFCQLQFDRGQVEIKEKLGNEYNFPVVHLSQLLGLAMGMDPKEVALDVNFISPEPLLQKLGY
What is the function of this protein?
Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
What are the official names of this protein?
H(2)/formate:CoB-CoM heterodisulfide,ferredoxin reductase subunit B2, CoB--CoM heterodisulfide reductase subunit B2.
What is the protein family that this protein belongs to?
Belongs to the HdrB family.
Protein: GRCA_ERWT9
Sequence: MITGIQITRSANSDLHNSFWLLDSETAQARCVCANAGYSEDQVVAVSDLGQIEYREIPLDVKPQVRVEGGQHLNVNVLSRETLEEAVENPDKYPQLTIRVSGYAVRFNSLTPEQQRDVITRTFTDSL
What is the function of this protein?
Acts as a radical domain for damaged PFL and possibly other radical proteins.
What are the official names of this protein?
Autonomous glycyl radical cofactor.
Protein: FAAA_HUMAN
Sequence: MSFIPVAEDSDFPIHNLPYGVFSTRGDPRPRIGVAIGDQILDLSIIKHLFTGPVLSKHQDVFNQPTLNSFMGLGQAAWKEARVFLQNLLSVSQARLRDDTELRKCAFISQASATMHLPATIGDYTDFYSSRQHATNVGIMFRDKENALMPNWLHLPVGYHGRASSVVVSGTPIRRPMGQMKPDDSKPPVYGACKLLDMELEMAFFVGPGNRLGEPIPISKAHEHIFGMVLMNDWSARDIQKWEYVPLGPFLGKSFGTTVSPWVVPMDALMPFAVPNPKQDPRPLPYLCHDEPYTFDINLSVNLKGEGMSQAATICKSNFKYMYWTMLQQLTHHSVNGCNLRPGDLLASGTISGPEPENFGSMLELSWKGTKPIDLGNGQTRKFLLDGDEVIITGYCQGDGYRIGFGQCAGKVLPALLPS
What are the official names of this protein?
Fumarylacetoacetase, FAA, Beta-diketonase, Fumarylacetoacetate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the FAH family.
Protein: HIS4_SHIFL
Sequence: MIIPALDLIDGTVVRLHQGDYGKQRDYGNDPLPRLQDYAAQGAEVLHLVDLTGAKDPAKRQIPLIKTLVAGVNVPVQVGGGVRSEEDVAALLEAGVARVVVGSTAVKSPDVVKGWFERFGADALVLALDVRIDEQGNKQVAVSGWQENSGVSLEQLVETYLPVGLKHVLCTDISRDGTLAGSNVSLYEEVCARYPQVAFQSSGGIGDINDVAALRGTGVRGVIVGRALLEGKFTVKEAIACWQNA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SF1_ARATH
Sequence: MESVEMNNPNSQTLDQPPPSSNGDTAPLALDHMNPQNSESVALNGSSTPIPDTNGSSAKPELLRPLLSENGVSKTLSGNDKDQSGGEEETTSRRKRRSRWDPPPSESINNPSAEGGTDSGTGTRKRKSRWADDEPRTQIQLPDFMKDFTGGIEFDPEIQALNSRLLEISRMLQSGMPLDDRPEGQRSPSPEPVYDNMGIRINTREYRARERLNRERQEIIAQIIKKNPAFKPPADYRPPKLHKKLFIPMKEFPGYNFIGLIIGPRGNTQKRMERETGAKIVIRGKGSVKEGRHQQKKDLKYDPSENEDLHVLVEAETQEALEAAAGMVEKLLQPVDEVLNEHKRQQLRELATLNGTIRDEEFCRLCGEPGHRQYACPSRTNTFKSDVLCKICGDGGHPTIDCPVKGTTGKKMDDEYQNFLAELGGTVPESSLKQSATLALGPGSSGSNPPWANNAGNGASAHPGLGSTPTKPPSKEYDETNLYIGFLPPMLEDDGLINLFSSFGEIVMAKVIKDRVTGLSKGYGFVKYADVQMANTAVQAMNGYRFEGRTLAVRIAGKSPPPIAPPGPPAPQPPTQGYPPSNQPPGAYPSQQYATGGYSTAPVPWGPPVPSYSPYALPPPPPGSYHPVHGQHMPPYGMQYPPPPPHVTQAPPPGTTQNPSSSEPQQSFPPGVQADSGAATSSIPPNVYGSSVTAMPGQPPYMSYPSYYNAVPPPTPPAPASSTDHSQNMGNMPWANNPSVSTPDHSQGLVNAPWAPNPPMPPTVGYSQSMGNVPWAPKPPVQPPAENPSSVGESEYEKFMAEMK
What is the function of this protein?
Necessary for the splicing of pre-mRNA.  Required during development and for abscisic acid (ABA) responses.
What are the official names of this protein?
Splicing factor-like protein 1, AtSF1, SF1 homolog protein.
What is the protein family that this protein belongs to?
Belongs to the BBP/SF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KUP1_RALSO
Sequence: MLGAIGVVFGDIGTSPLYALKECFNPEHGVPFSTQTVYGVLSMLFWSMTLVVSIKYVVFVMRADNNGEGGILALTALAMRASSGGARTIRTLMLLGLLGASMFYGDAVITPAISVLSAVEGMEVMTPALQPWVLPLSLIVLVGLFLLQKHGTHVVGRLFGPVMLFWFVLLGLIGLFSVLRSPQILVALNPVHAIEFMFRHAVQAFIVFGSVFLALTGAEALYADMGHFGARPIRYAWFYIAMPCLLLNYFGQGALLLREPSALQNPFFLLMPTWAVAPTIVLATAATVIASQAVISGAFSMTAQAVHLGYAPRMKILYTSDVEIGQIYVPVVNYALLLLVVAVVLAFGKSDNLAAAYGIAVTTTMLLTTGLVTVVMRNAWKWSLPAVALLGTVFLAVDLSFFGANLLKVAAGGWFPLLLGGLIFFLMVTWHTGTQLLKARNVEGGIPLEPFMEGLLSHPPYRVDGTAVYLTPSIEFVPLALLHNLKHNHVLHSRVLFIHFRTQAVPYVEPAKRLVVKTIGDNLYAVAADFGFKETPAVDEIVRMVGERLGIVFEDMETSFFITRATVVPSQLPGMAMWREALFAWMQHNSAKPSDFFRIPANRLVELGSKVEI
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup 1.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EMIL2_MOUSE
Sequence: MCQETPPRPRAPSRWTPALLALLALGGAGLCHASSQPGYHARPSARNKNWCAYIVNKNVSCTVQEGSESFIQAQYNCPWNQMPCPSALVYRVNFRPRFVTRYKIVTQLEWRCCPGFRGPDCQEGPKDHMKTPRPPSARPKNNLKKATDTDPSQVSQPKKTLSPTNAVEPGQVADAKQGPPELQQSKVQVLEEKVVRLTRMVLDLQSTVVGLKENLKHTIQDDGRKEPDSWLGPLHPQPTPDSPLAGDAEPSQLPGIPSSKESGMKDIKSELAEVKDTLKTKSDKLEELDGKVKGYEGQLKQLQEAAQGPTVTMTTNELYQAYVDSKIDALREELMEGMDRKLADLKNTCEYKLVGLQQQCDDYGSSYLGVIELIGEKEASLKKDIADLRAQLQDPVAQPSCCNGQKSSDFGPQIKALDQKIERVAEATRMLNGRLDNEFDRLSVPEPDADFDARWTELDARINVTEKNAEEHCFYIEETLRGTINGEVDDLRKLLNEKIHSLEDRLGIVLQAANSSDVELTPMGPALPEQPGAENEQVLMELSRLKDKVQVVEDFCLQSLPHGIDGALPSVEDLTHVSLSLLESLNDTMHRQFQETSHSIQKLQEDVNALHSQLNHSECTGTYLQNGVSDSRTGDSMEASGFTKTGEQERTVGTVPSPGTPAAPCCGQLEERWQKLQNQMLAELDTCKESAHGVQSGVSAIEGRVFQLEQTCRRLDTISGSLQRIKEGLGKHVGSLWNCIRQMNGTLKSHSRDISGLKNSVQQFYSHVFQISTDLQDLVKFQPSATEEPSEATEGPSGKTPLESTRPSEEAPTEPPRLTPLPEDPAGPPQTGQQPVLPQRPLQPPPLPAWPGRTGLPFLPGSSGVIMETGEAGPPGRMGVSGRGLPRGVDGQMGQGPIHSSEGYAGAPGYPKSPPVTTPGVPLPTLVSFSAGLTQKPFPSDGGVVLFNKVLVNDGDVYNPNTGIFTAPYDGRYLITATLTPERDTYVEAVLSVSNASVAQLHTAGYRREFLEYHRPPGAVHTCGGPGAFHLIVHLKAGDGVNVVVTGGRLAHTDFDEMYSTFSGVFLYPFLSHL
What is the function of this protein?
May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly.  Has cell adhesive capacity.  Major component of the cochlear basilar membrane (BM) which may contribute to the developmental assembly or function of the BM.
What are the official names of this protein?
EMILIN-2, Basilin, Elastin microfibril interface-located protein 2, Elastin microfibril interfacer 2.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Note=Found mainly at the interface between amorphous elastin and microfibrils.
Protein: PXPA_STAAB
Sequence: MRVDLNCDLGEAFGNYSFGGDHQIIPLITSANVACGFHAGDENVMNETVKLAKAHNVAVGAHPGLPDLKGFGRRNIDISNEEIYNLMIYQLGALQGFCRIHQVKINHVKPHGALYQMGAKDREIASVIAQAVYDFDPSLVLVGLANSYLISEAKNVGLITASEVFADRRYEDDGQLVSRKESDAVITDTDEALKQVLKMVKENKVISKNNKEVTLQADTICVHGDGEHALLFVSKIREILMKEGIDIQSL
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: KCY_METAC
Sequence: MQITVSGLPGSGTTTLSRLLSDYYELELISSGEIFRRMAKERGMSLADFGAMAEKDPSIDLDIDKNQKSIIHTQDDLVLESRLAGHMAKGVPNVLKIWIKAPLLTRVKRIQRREKTISFDEELAKTVEREKSEALRYKNYYGIDITDLSIYDIVIDSEKWNQYQTLDILRVAIDALVGPE
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TF2B_PYRNV
Sequence: MTSPNPPSSGKPLKLRINRDSEGYLSLVTDTGEVYRCPICGNDKFIYNYERGEVVCIVCGAVVQEQLLDLGPEWRAFTSEERGQRARTGAPLTRLISEALTTVIDWRDKDVSGKELDIKRKLEVIRLRKWQTRARVQTSYERNFIQAAQELERLRSSMGIPRPCIEQALEIYRQALEKELVRGRSVEAMAAAALYMACRMMKMPRPLDELVRYTKASRREVARCYRLLLRELNVKVPISDPTLYISRIAEQLKLSGEVVKTAIDILQKAKKAGITAGKDPAGLAAAAVYIASLMHGDNRTQKDFAVAAGVTEVTVRNRYKELAKALNIKVPVK
What is the function of this protein?
Stabilizes TBP binding to an archaeal box-A promoter.  Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
What are the official names of this protein?
Transcription initiation factor IIB, TFIIB.
What is the protein family that this protein belongs to?
Belongs to the TFIIB family.
Protein: Y1558_STAAC
Sequence: MDMNFDLYMNGVVEQARNEIESAGYEQLTTAEDVDKVLKQDGTTLVMINSVCGCAGGIARPAASHALHYDVLPDRLVTVFAGQDKEATQRAREYFEGYAPSSPSFALVKDGKITEMIERHQIEGHDVMNVINQLQTLFNKYCEER
What are the official names of this protein?
UPF0403 protein SACOL1558.
What is the protein family that this protein belongs to?
Belongs to the UPF0403 family.
Protein: RL5_THEVB
Sequence: MSQRLKDHYNKTVVPQLMQQFQYKNIHQVPKIVKVTVNRGLGEAAQNAKALEATLAEIATITGQKPVVTRAKKAIAGFKIRKGMPVGVAVTLRSERMYAFLDRLINLALPRIRDFRGVNPKSFDGRGNYTLGLREQLIFPEVNYDDIDQIRGMDVSIITTANTDEEGRALLKAMGMPFREN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: MED20_CAEBR
Sequence: MGVSWVFEAEQTAKSVERILEGIGAELMGQFQVDVIPYNPATPSTDYATNIVMHHSKCPQSTFSICPKTDFRVSPKAVCDRGFDLILGKLAGGLVIDNAGKIEINGNEYNIHSDWTVRVGTATQGTTVKGVVVEVEYDPTVIIVQCREMMAEFIKQVFNKYHETQPEIFKITEKPERYSTLDTMWQYLQIAAKLRKKT
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 20, Mediator complex subunit 20.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 20 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: S38A1_PONAB
Sequence: MMHFKSGLELTELQNMTVPEDDNISNDSNDFTEVENGQINSKFISDRESRRSLTNSHLEKKKCDEYIPGTTSLGMSVFNLSNAIMGSGILGLAFALANTGILLFLVLLTSVTLLSIYSINLLLICSKETGCMVYEKLGEQVFGTTGKFVIFGATSLQNTGAMLSYLFIVKNELPSAIKFLMGKEETFSAWYVDGRVLVVIVTFGIILPLCLLKNLGYLGYTSGFSLSCMVFFLIVVIYKKFQIPCIVPELNSTISANSTNADTCTPKYVTLNSKTVYALPTIAFAFVCHPSVLPIYSELKDRSQKKMQMVSNISFFAMFVMYFLTAIFGYLTFYDNVQSDLLHKYQGKDDILILTVRLAVIVAVILTVPVLFFTVRSSLFELAKKTKFNLCRHTVVTCILLVVINLLVISIPSMKDIFGVVGVTSANMLIFILPSSLYLKITDQDGDKGTQRIWAALFLGLGVLFSLVSIPLVIYDWACSSSSDEGH
What is the function of this protein?
Symporter that cotransports short-chain neutral amino acids and sodium ions from the extraccellular to the intracellular side of the cell membrane.  The transport is elctrogenic, pH dependent and driven by the Na(+) electrochemical gradient.  Participates in the astroglia-derived glutamine transport into GABAergic interneurons for neurotransmitter GABA de novo synthesis (By similarity).  May also contributes to amino acid transport in placental trophoblast (By similarity).  Regulates synaptic plasticity (By similarity).
What are the official names of this protein?
Sodium-coupled neutral amino acid symporter 1, Amino acid transporter A1, N-system amino acid transporter 2, Solute carrier family 38 member 1, System A amino acid transporter 1, System N amino acid transporter 1.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Restricted to the somatodendritic compartment of neurons. Found in the cellular processes of neurons in the developing brain.
Protein: IFNG1_ORYLA
Sequence: MMMMALMKVILCLWLTVTGVSASYVPQEMNKTIQNLLQHYKIPLVERFNGNPVFPKDSMDGNVEMKMIFMHGVLETYEDLIGHMLKQLPTASPPLGSNQDKPASPGTSNDDAAPVKADVRSKLMYILEKIQFLKTHRYQEQEKLLHRLQNLKKIQMDNRTVQSKALWELPQLFEKASSLADNTMRRRRRRQARNRMRLKA
What is the function of this protein?
Probable cytokine.
What are the official names of this protein?
Interferon gamma 1, Interferon gamma 2.
What is the protein family that this protein belongs to?
Belongs to the type II (or gamma) interferon family.
What are the subcellular locations of this protein?
Secreted.
Protein: YH2B_SCHPO
Sequence: MPEKDWIGEFGPSKFKSPIDKLNQLLPESNDPSILYETSQHLLSEFDKTLNDSLRVLNQQINQVSEVLPRLPTMISALDRESKRLFESCEKMDPEPSALMPLQELEKIRSNIQLTISQIDNLTP
What are the official names of this protein?
Uncharacterized protein C1A4.11c.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GPXC_WUCBA
Sequence: MSAQLLILSHVVLLQLIVAQLGPKIGKQFLKPKQCEITNQTVYDFHAQMLNGAQRSLTEYRNKVLLIVNVATYCAYTMQYRDFNPILGSNSNGTLNILGFPCNQFYLQEPAENHELLNGLKYVRPGHGWEPHKNMHIFGKLEVNGENDHPLYKFLKERCPPTVPVIGKRHQLIYDPIGTNDVIWNFEKFLVDKKGRPRYRFHPENWVQGTAVKPYIDELEREI
What is the function of this protein?
Could inhibit the oxidative burst of leukocytes and neutralize the secondary products of lipid peroxidation, thus providing the resistance of these parasites to immune effector mechanisms and their persistence in the mammalian host.  It may also be involved in the formation of cross-linking residues such as dityrosine, trityrosine and isotrityrosine identified in cuticular collagen.  Highly cross-linked external cortex may also serve to protect the parasite from immune attack.
What are the official names of this protein?
Cuticular glutathione peroxidase, Cuticular glycoprotein gp29, Major surface antigen gp29, gp30.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted into the cuticle and ultimately released into the medium.
Protein: LDH_CLOBL
Sequence: MIKKRNTTKISVIGAGSVGATTAYALMLSGVATEIVLVDVNKSKTEGEAMDLSHGADFVKPVNILSGDYKDTEGSDIVVITAGAAQKVGETRLQLINKNINIFKSIIPEVVKYNKDAILLVVSNPVDVLSYVTYKLSGFPKERVIGSGTVLDTSRLKHEIGKRYKIDPRNVNTYIMGEHGDSEIATWSVTNIQNIKIDEYANKENLEYNDNFRKEVYENVKNAAYEVINRKGATFYAIALAVTRIVKAILGDEKTILPVSTLVENYYGIKDVYLGMPCIVGGSGIEKALSIDLNKTEASKLVKSAETLKNTLNNASGL
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARL3_YEAST
Sequence: MFHLVKGLYNNWNKKEQYSILILGLDNAGKTTFLETLKKEYSLAFKALEKIQPTVGQNVATIPVDSKQILKFWDVGGQESLRSMWSEYYSLCHGIIFIVDSSDRERLDECSTTLQSVVMDEEIEGVPILMLANKQDRQDRMEVQDIKEVFNKIAEHISARDSRVLPISALTGEGVKDAIEWMIVRLERNKKSRPPIYK
What is the function of this protein?
Involved in the targeting of ARL1 to the Golgi.  Can bind and hydrolyze GTP.
What are the official names of this protein?
ADP-ribosylation factor-like protein 3, Arf-like GTPase 3.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
What are the subcellular locations of this protein?
Golgi apparatus.