PharMolix/UniProtQA huggingface dataset:
Protein: Y1708_LACPL
Sequence: MSDVNKKFDSKKDQLSGKAKEVEGKVTGDRAREAQGKTQSLMGKAKDKLADAEETVKGVVDEAKDKMKKKSDD
What are the official names of this protein?
UPF0337 protein lp_1708.
What is the protein family that this protein belongs to?
Belongs to the UPF0337 (CsbD) family.
Protein: SURA_VIBPA
Sequence: MKIWKSILFTTLLSCGAVAAPVELDKVAVIVNDGVILQSDINTAMKTLQANARQSGKSLPSASVLKEQVVEKLIIDTLQGQEADRIGVRIDDNRLNQAIAEIARNNNQSVEELAASVQAEGLSYPEFREQIRKEIAASEARNALVRRRINILPAEVDSLADQLAKETNATVQYKIGHIQLRFTDGQDKSEVEAQAKALVKKLNDGADFTEMAYTYSKGPKALQGGDWGWMRKEEMPTIFADQIKMQNKGSIIGPFRSGVGFHILKIEDVKGLETVAVTEVNARHILIKPTVILSDEGAKKQLNEFVRRIKAGEATFAQLASQYSQDPGSAAQDGELGYQTPDLYVPEFKHQVETLPVGSISEPFKTVHGWHIVEVLDRRQVDRTDSAMKNKAYRILFNRKFNEEAGAWMQELRASAFVEIVDDNNDN
What is the function of this protein?
Chaperone involved in the correct folding and assembly of outer membrane proteins.  Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins.  May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
What are the official names of this protein?
Chaperone SurA, Peptidyl-prolyl cis-trans isomerase SurA, PPIase SurA, Rotamase SurA.
What are the subcellular locations of this protein?
Periplasm. Note=Is capable of associating with the outer membrane.
Protein: GLPK_BACLD
Sequence: MEKYILSLDQGTTSTRAIVFNKAGEIVHIAQKEFRQYFPNPGWVEHNANEIWGSVLSVIASALSESGIEAGQIAGIGITNQRETTVVWDKHTGKPVYNAIVWQSRQSAEICQELKEKGYEETIREKTGLLIDPYFSGTKVKWILDHVEGAREKAENGDLLFGTIDSWLIWKMSGGKAHVTDYSNASRTLMFNIYDLKWDDELLDILGVPKSMLPEVKPSSHVYAETVDYHFFGKNIPIAGAAGDQQAALFGQACFEEGMVKNTYGTGCFMLMNTGEKAIKSEHGLLTTIAWGIDGKVEYALEGSVFVAGSAIQWLRDGLRMFKDAKESEKYAVRAESADGVYVVPAFVGLGTPYWDSDVRGAVFGLTRGTTKEHFIRATLEALAYQTKDVLDAMKEDSGIPVKTLRVDGGAVKNNFLMDFQGDILDVPVERPEINETTALGSAYLAGLAVGFWSDRSEIKDQWQLDKRFEPKMEEKERESLYNGWKKAVNAARAFK
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: CH10_ANASL
Sequence: MAAVSLSVSTVKPLGDRVFVKVSASEKRPRRLYFPDTAKEKPQVGEVVALGAGKRNDDGSRQELEVKVGDLLLYSKYAGTDVKLGTEEYVLLSEKDILAMVG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURC_ECOBW
Sequence: MNTQQLAKLRSIVPEMRRVRHIHFVGIGGAGMGGIAEVLANEGYQISGSDLAPNPVTQQLMNLGATIYFNHRPENVRDASVVVVSSAISADNPEIVAAHEARIPVIRRAEMLAELMRFRHGIAIAGTHGKTTTTAMVSSIYAEAGLDPTFVNGGLVKAAGVHARLGHGRYLIAEADESDASFLHLQPMVAIVTNIEADHMDTYQGDFENLKQTFINFLHNLPFYGRAVMCVDDPVIRELLPRVGRQTTTYGFSEDADVRVEDYQQIGPQGHFTLLRQDKEPMRVTLNAPGRHNALNAAAAVAVATEEGIDDEAILRALESFQGTGRRFDFLGEFPLEPVNGKSGTAMLVDDYGHHPTEVDATIKAARAGWPDKNLVMLFQPHRFTRTRDLYDDFANVLTQVDTLLMLEVYPAGEAPIPGADSRSLCRTIRGRGKIDPILVPDPARVAEMLAPVLTGNDLILVQGAGNIGKIARSLAEIKLKPQTPEEEQHD
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSMG1_PAPAN
Sequence: MAATFFGEVVKAPCRAGTEDEEEEEEEEGRRETPEDREVRQQLARKREVRLLRRQTKTSLEVSLLEKYPCSKFIIAIGNNAVAFLSSFVMNSGVWEEVGCAKLWNEWCRTADTTHLSSTEAFCGFYHLKSNPSVFLCQCSCYVAEDQQYQWLEKVFGSCPRKNMQITILTCRHVTDYKTLESTGSLPSPFLKALKTQNFKDPACCPLLEQPNIVHDLPAAVLSYCQVWKIPAILYLCYTDVMKLDLITVEAFKPILSTRSLKGLVKNISQSTEILKKLMTTNEIQSNIYT
What is the function of this protein?
Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG2.  The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization (By similarity).
What are the official names of this protein?
Proteasome assembly chaperone 1.
What is the protein family that this protein belongs to?
Belongs to the PSMG1 family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum.
Protein: EFTU_STAAW
Sequence: MAKEKFDRSKEHANIGTIGHVDHGKTTLTAAIATVLAKNGDSVAQSYDMIDNAPEEKERGITINTSHIEYQTDKRHYAHVDCPGHADYVKNMITGAAQMDGGILVVSAADGPMPQTREHILLSRNVGVPALVVFLNKVDMVDDEELLELVEMEVRDLLSEYDFPGDDVPVIAGSALKALEGDAQYEEKILELMEAVDTYIPTPERDSDKPFMMPVEDVFSITGRGTVATGRVERGQIKVGEEVEIIGLHDTSKTTVTGVEMFRKLLDYAEAGDNIGALLRGVAREDVQRGQVLAAPGSITPHTEFKAEVYVLSKDEGGRHTPFFSNYRPQFYFRTTDVTGVVHLPEGTEMVMPGDNVEMTVELIAPIAIEDGTRFSIREGGRTVGSGVVTEIIK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_STRS7
Sequence: MTAIIERAPAKINLGLDIQGKRPDGYHDLSMVLVSVDLCDYITVDHLEEDRILLTSNCPRLPINEHNDVYKAAYLLKERFQISTGVSIFLDKRVPVCAGMGGGSSDAAAAIRALNQLWQLKLSPRQMIDIGMQIGSDVPYCLFAGCAQVTGKGEVVKPINGRLSSWVVLVKPEFGISTRTIFWDIDCETISRVPIEDLVSAIEAGDYQRLLATMGNSLEDISIAKRPFIQKVKDKMLQSGADIALMTGSGPTVFALCQTEKQANRVVNSLKGFCKEVYKVRTL
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: CLPP_COFAR
Sequence: MPIGVPKVPFRSPGEEDASWVDVYNRLYRERLLFLGQAVDSEISNQLIGLMIYLSIEDDTKDLYLFINSPGGWVIPGVAIYDTMQFVRPDVHTICMGLAASMGSFILVGGEITKRLAFPHARVMIHQPASSFYEAQAGEFILEAEELLKLRETLTRVYVQRTGKPLWVVSEDMERDVFMSATEAQAYGIVDLVAVE
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: TOP3_STAS1
Sequence: MKSLIIAEKPSVGRDIANTLNINEKRNGYFENNKYIVTWALGHLVTNATPEQYDASYKEWKLNDLPIIPNKMKTIVISKTRKQFSTVQSLINNNKVKDIIIATDAGREGELVARLILDKAHNKKPTKRLWISSVTNKAIKEGFNKLQDGRKFNNLYHAALARSEADWIVGINATRALTTKYDAQLSLGRVQTPTIQLVQMRQNEINHFKPQTYYTMKLNAAGLTFHCTKPQSHPDKTVLESIKKAIDGQSGHIASISKTHKKAYPQQLYNLTDLQQDAYKRFHLGPKETLNTLQTLYERHKLVTYPRTDSNYLTDDMVDTLKDRLKAIMATSLKDMAKAQMSQTFSSKQRFVNNNKVSDHHAIIPTEVRPDINQLSQRESKIYMMIAQRYLENLMPPHEYEAIAIELKVGQHTFTFKDKVTTKLGFKAIYENKESINTQIDQLQKGTKLNVTKILIEEHETTAPPYFNEGSLLKAMESPQKFFDLSDKKHDKTLKDTGGIGTVATRADIIEKLFNMNAIEARDGKIKVTSKGKQILELAPQKLTSPLLTAEWEEKLLLIEQGKYNASQFISEMKAFTNQVVNEIKESEQNYKHDNLTTTECPTCGKFMIKVKTKNGQMLVCQDPQCKTKKNVQRKTNARCPNCHKKMTLFGRGKDAVYRCVCGHTETQAQMDKRHKNKKSDKVNKKDLKKYMNNDEGIENNPFQDALKGLKF
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.  The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils.  Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.
What are the official names of this protein?
DNA topoisomerase 3, DNA topoisomerase III.
What is the protein family that this protein belongs to?
Belongs to the type IA topoisomerase family.
Protein: PLSX_MARN8
Sequence: MPHGRVVNTPVTIAIDAMSGDRGAAVVVHAALEAVRENEALSLVLVGIRSELEALLHEGHARIRIVEAADVVRMNERPSHALRHKKNSSMAIALSLVRDGEAQGCVSAGNTGALMAFGRSIIRMYPGIERPAIAKLIPSLRGRCHVLDLGANVDSTAENLYQYALMGSLMASAICRQSEPRVALLNVGEEEIKGNEQVRLASHMLAQCDTINYIGYVEGSDLFRDVADVVVCDGFVGNIALKTGEGVAGLLIELLEQAFTRSMYGRFVGLLARPIIGRLLQLMDPSRHNGASLLGLQGVVIKSHGNANERAMLAAIRQAVREVQLEVPRRINERLDDLML
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: F16A1_HALMA
Sequence: MSKSLDISTTEAEQTVTEVIDTIVATTPDVRRAVADYRGQSNSVNPTGDDQLAADLRADELFEQRVLGIDGVASYASEERADVKTTDGRLHVAMDPLDGSSNLEPNSGMGTIFGIYSEQPPTVGTNLLAAGFVIYGPITSMVVARDGSVREYILEDGDKRVVDDDVTVPEDPTVFGFGGGVDSWTDEFESYAEAVRHELKLRYGGAMVADINQVLTYGGIFSYPALESRPEGKLRVQFEGHPMAYILESAGGRSSDGDQSLLEIEPDELHERTPLYLGNDDLIDRLEANID
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1 1, FBPase class 1 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SDHF2_PENRW
Sequence: MSAPRILHRVARPVPSSISTITRLNRQFGTTALRLKDGSDEASPEVKAHRANQANKAPNQFVPNTTSTMTKDFVNVGQKPAPPEMLNSANPNYRPSDPYPGRIEHFTGGRQDNGAQKPELGVGEMEGITFKVEPLKRVGEELATKRARLLYQSRKRGILESDLLLSTFADVYLGKMNYDQLVEYDSFLDENDWDIYYWATQDSPEEISPSTPKEDTITETWKESGAKSGEWAQTIGAFRAAYRPVPSRWQNSEVLALLREHVRDKSATGFEKAKNKKTGGGGGLGRMPDVQVFNSGHIVHRRHVLRMLYI
What is the function of this protein?
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.
What are the official names of this protein?
Succinate dehydrogenase assembly factor 2, mitochondrial, SDH assembly factor 2, SDHAF2.
What is the protein family that this protein belongs to?
Belongs to the SDHAF2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: GLGB2_RHIL3
Sequence: MNVERSELLAGIGQDALWALIEGRHGDPFSILGPHQSGGMTIVRVYLPGAEAVDLIDATSGRVVAPFSIAHPSGLFAATVASRTGYRLRITWPDAVQITEDPYSFGLLLGELDLHLISEGTHYSLSRTLGAVAMSIDGISGVRFAVWAPNARRVSVVGDFNAWDGRRNPMRLRPSAGVWELFIPRLAPGERYKFEIVDAEGTCLPQKADPVARASEAAPSTASIVASSTPFRWTDDGWMKGRSRQDRLEGAFSVYEVHVGSWLRDQKDGNRSLDWVELSQRLVPYVSDMGFTHIELLPIMEHPFGGSWGYQPLGLFAPTGRYGTPEDFAYFVDRCHGAGLGVILDWVPAHFPTDVWGLARFDGSALYEHEDPREGFHRDWNTLIYNLGRNEVKGFLIASALEWLERYHIDGLRVDAVASMLYRDYSRNEGEWIPNQYGGRENLEAVEFFKHLNSIIHERCPHAMTIAEESTAWPGVTKPPEQGGLGFDIKWNMGWMHDSLSYIEKDPIYRSYAHGTMTFGMIYAYSERFILPISHDEVVYGKGSLLTKMPGDEWQKFANLRSYLAFMWGHPGKKLLFMGSEIAQPSEWNHDGSVTWDVLDQPQHVGIQRLVKDLNGLYGDEPALQFGDFHSEGFEWAAADDAVNSVLGMLRYAPDRASSVLVMSNFTPVPRYGYRIGVPSDGVWIERITTDAREYGGSGLVNGAVSSEPVPAHGRPVSLSLTLPPLSTIFLQGPSP
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB 2, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase 2, Alpha-(1->4)-glucan branching enzyme 2, Glycogen branching enzyme 2, BE 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: ARLY_BURM7
Sequence: MTSQLHKKGEAWSARFSEPMSELVKRYTSSVFFDKRLALVDIAGSLAHAGMLAAQKIISADDLAAIERGMAQIKGEIERGEFEWQLDLEDVHLNIEARLTALIGDAGKRLHTGRSRNDQVATDIRLWLRGEIDRIGGLLNDLRGALIDLAEQNADTILPGFTHLQVAQPVTFGHHLLAYVEMFSRDAERMRDCRARVNRLPLGAAALAGTSYPIDRHAVAKTLGFDGICANSLDAVSDRDFAIEFTAAAALVMTHVSRFSEELVLWMSPRVGFIDIADRFCTGSSIMPQKKNPDVPELARGKTGRVNGHLMALLTLMKGQPLAYNKDNQEDKEPLFDTVDTVADTLRIFAEMVAGITVKPDAMRAAALQGFSTATDLADYLVKRGLPFRDAHEAVAHAVKVCDARGIDLADLTLDEMKQELPNVAHLIGEDVFDYLTLEGSVASRNHPGGTAPDQVRAAAKAARAALGQ
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TDH_SALNS
Sequence: MKALSKLKAEEGIWMTDVPEPEVGHNDLLIKIRKTAICGTDVHIYNWDDWSQKTIPVPMVVGHEYVGEVVGIGQEVKGFKIGDRVSGEGHITCGHCRNCRGGRTHLCRNTTGVGVNRPGCFAEYLVIPAFNAFKIPDNISDDLASIFDPFGNAVHTALSFDLVGEDVLVSGAGPIGVMAAAVAKHVGARHVVITDVNEYRLELARKMGVTRAVNVAKESLNDVMAELGMTEGFDVGLEMSGAPPAFRTMLDTMNHGGRIAMLGIPPSDMSIDWTKVIFKGLFIKGIYGREMFETWYKMAALIQSGLDLSPIITHRFSIDDFQKGFDAMRSGQSGKVILSWD
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTAS_STAAM
Sequence: MADLLNVLKDKLSGKNVKIVLPEGEDERVLTAATQLQATDYVTPIVLGDETKVQSLAQKLDLDISNIELINPATSELKAELVQSFVERRKGKATEEQAQELLNNVNYFGTMLVYAGKADGLVSGAAHSTGDTVRPALQIIKTKPGVSRTSGIFFMIKGDEQYIFGDCAINPELDSQGLAEIAVESAKSALSFGMDPKVAMLSFSTKGSAKSDDVTKVQEAVKLAQQKAEEEKLEAIIDGEFQFDAAIVPGVAEKKAPGAKLQGDANVFVFPSLEAGNIGYKIAQRLGGYDAVGPVLQGLNSPVNDLSRGCSIEDVYNLSIITAAQALQ
What are the official names of this protein?
Phosphate acetyltransferase, Phosphotransacetylase.
What is the protein family that this protein belongs to?
Belongs to the phosphate acetyltransferase and butyryltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIG1C_ARATH
Sequence: MAFPQRKRTPSFSSSVLDSVYRSIDESDGLQSDLKGSINENVSSSSSSPSPNKKDDKLTTLRRAIMDEEHWLYARSSTTTTNSSDSSSFSSSEAESYRTKRRLRKLAEQGKRSGDERQRTKRTVMDNDSRLFSKSDDDKKPKAVKIIEELKRSKQPVSPGARLTSFLNSIFQSNAKKVKLCSVGKTTDVKSSSSKSCFSRTRNKTDNNNNNCKKLERSIRFYPVRVTIDGDCRDYAQKHITRVRKPIPEFTAKKSVKEEIKTNDHHTEFTCITRNIGLKDFVRSNKYEGKEEEEDAWSHSSSDLFELDSYRIGMGRYLKELPVYETTDFKTNQAIARSLLL
What is the function of this protein?
Involved in auxin transport.  Regulator of the auxin signaling pathway.
What are the official names of this protein?
Protein BIG GRAIN 1-like C.
What is the protein family that this protein belongs to?
Belongs to the BIG GRAIN 1 (BG1) plant protein family.
What are the subcellular locations of this protein?
Cell membrane.
Protein: CLPX_NOCSJ
Sequence: MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEELSEGAEVSLDELPKPKEIFEFLNSYVIGQEQAKKSLAVAVYNHYKRVQAGLQPMSGKHSKEEVVEVAKSNILVIGPTGCGKTYLAQTLARMLNVPFAIADATALTEAGYVGEDVENILLKLIQAADYDVKKAETGIIYIDEIDKVARKAENPSITRDVSGEGVQQALLKIIEGTTASVPPQGGRKHPHQEFIQIDTTNILFVVGGAFAGLEHIIEQRVGKKTLGFTAEVRGKAEREAEDLLAQVRPEDLTKFGLIPEFIGRLPLIASVSKLDQEALVQILTEPRNALVKQYQKLFELDGVELEFTPDAIEAIADNALERGTGARGLRAIIEEVLLHVMYDVPSRGDIAKVIVTREVVMDGVSPTLIPRESEKKKKSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: RBSD_THEMA
Sequence: MKKVGILNSEISKIVADMGHMDTLAVVDLGFPIPQGVKKVDLVVDRGKPGLMEVIEILLRELKVERIILAKEMDEKSIQTKQELLKLIEKMNGPVEVVTVPHKEFKEMSKNVKGIIRTGADIPYSNVILVGGVIF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP2_BTV13
Sequence: MEELVIPVITERFDKRLVGRYDYVIELARPEGDEWSGHDVTHIPDRRMFDIKVQPIRDAIDYKPVENDGEVLPRILDMSIACYDMRKRMMKRDGVDFVSDTKWLEWMIQDSMDVQPLKVDMKEDHSTVQYDMFSAKLHVDSRKADTTSYNILALETKEGAQCHHVHTNIWNHMIRNHLFHAVQESCYIFKPTYKLTVNSERRTPDEDFQIGNPQFLTLRRNQQIFLGDDAYKKTAKGLVQVLVNGVVPDIIRNEIAALDAIRDKWIQGNYERTHIKSLELCNLLSAIGRKMVNLEEEPKDERDLSLRFQHKLDDKFAKNDQERNVIFAQKSQRNDQDRFYVLMVIAASDTNNSRVWWSNPYPCLRGALIAAECKLGDVYYKLRSWYEWSVREGYKPRDLDRQYEKYIVGRVNLFDLEAEPGTKVLHWEYELISKLYTVSNHEGNQCDLHPDEGEIVTKFDDTRYSDMIQTIINEGWKQNDFKMFKMLKDEGNPLLYDLEKDIKLDRVSRVVFPPYFDQWTYVPMFNARIKPCEVEVGERKNIDPYVKRTHRPLKADCIELMRYHMSQYMDLRVSLQGTSLSIKQTPSSIHQSLARDASYAEILSRRRENLDYKSQCPIVTNLFLLEKFFLLIFTTMEKHYWEMDDDETEYEHPKIDPSKFEVEGTLHDVSQVMVHLFDRFFEKRRFLRTVDESRWILHLIRSASGARRLEVLSRFFPAFSDGLRIREFKKVRDIMLLNFLPFLFLTGDNIAYEHRQWAVPVIFYADKIMIIPAEVGAYYNRFGLTCILELMMFFPSYDTRNENLSEDVRACIGPIINYYLDTTISNGGIQTSIVSTKALLYETYLSSICGGFSEAILWYLPITHPSKCLIALEVSDALTSPELRIDKIKRRFPLSSNHLKGIVQISVRPGRTFSVVTQGIVKHRVCKKTLLRYRCDVILIQTPGYVFGNDELLTKLLNI
What is the function of this protein?
The VP2 protein is one of the two proteins (with VP5) which constitute the virus particle outer capsid.  It is the major target of the host immunogenic response.  Responsible for viral attachment to target host cell, probably by binding to sialic acid.  This attachment induces virion internalization predominantly through clathrin-dependent endocytosis (By similarity).
What are the official names of this protein?
Outer capsid protein VP2.
What is the protein family that this protein belongs to?
Belongs to the orbivirus VP2 family.
What are the subcellular locations of this protein?
Virion.
Protein: CYB_CEBAL
Sequence: MTSPRKTHPLMKIINSSFIDLPTPSNISSWWNFGSLLGACLMIQITTGLFLAMHYTPDTSTAFSSVAHITRDINYGWMIRLLHANGASMFFVCLFLHTGRGLYYGSFLFLNTWNIGTILLLMTMATAFMGYVLPWGQMSFWGATVITNLLSAIPYTGHNLVQWIWGGFSVDKPTLTRFFTFHFILPFIITALATIHLLFLHETGSNNPSGMASSPDKIMFHPYYTTKDIFGLTLLLLLLTSLTLFTPDLLTDPDNYTLANPLNTPPHIKPEWYFLFAYTILRSIPNKLGGVLALLLSIMILTIIPATHLSKQQSMMFRPITQILFWTLAADLLTLTWIGGQPVEYPFEAIGQTASIAYFLIITLIPLSALTENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: 6PGL_CHLPN
Sequence: MATLINFNDTNKLLLTKQPSLFIDLASKDWIASANQAIKQRGAFYVALSGGKTPLEIYKDIVINKDKLIDPSKIFLFWGDERLAPITSSESNYGQAMSILRDLNIPDEQIFRMETENPDGAKKYQELIENKIPDASFDMIMLGLGEDGHTLSLFSNTSALEEENDLVVFNSVPHLETERMTLTFPCVHKGKHVVVYVQGENKKPILKSVFFSEGREEKLYPIERVGRDRSPLFWIISPESYDIADFDNISSIYKMDIL
What is the function of this protein?
Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
What are the official names of this protein?
6-phosphogluconolactonase, 6PGL.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
Protein: RS17_THEKO
Sequence: MREIGLRVQPPAEVCNDPKCPWHGNLKIHGRYVEGIVVSDKGKKTVVVERQYYHYLKKYERYELRKSKVHAHNPECINAKVGDKVLIAETRPISKTKSWVVVAVLQRAERAEEV
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: TM11E_MOUSE
Sequence: MYRSCVVRARKRTCVEPWVIGIISFLSLIVLAVCIGLTVHYVRYNHRRTYNYYSTLSFTSDKLYSEFGREASKNFTEMSQRIETMVKHAFHKSPLRGQLVKAHIIKFSKEDDGVLAHMLLIFRIRSTEDPETVHKIIEYVLHEKLKYATGPPNVDPESVKIKKINKTESDNYFNHCCGTRRNKSTVQTSVRIVGGTPVEEEEWPWQSSLRWDGSHRCGATLINNTWLVTAAHCFRTHKDPSRWSATFGATLQPRKLTTGIRRIIVHEKYKYPSHDYDIALAELSKPVPCTNAVHKVCLPDANHEFQPGQRMFVTGFGALKNDGFTQNNLRQVQVDYIDTQTCNQPQSYNGAITPRMLCAGFLKGEKDACQGDSGGPLVTADVRDIWYLAGVVSWGDECGQPNKPGVYTRVTAFRHWIASNTGI
What is the function of this protein?
Serine protease which possesses both gelatinolytic and caseinolytic activities.  Shows a preference for Arg in the P1 position.
What are the official names of this protein?
Transmembrane protease serine 11E, Serine protease DESC1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Transmembrane protease serine 11E catalytic chain]: Secreted. Note=Activated by cleavage and secreted.
Protein: FIS_ECO7I
Sequence: MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.
Protein: MTNN_HAEIE
Sequence: MKIGIVGAMAQEVEILKNLMADRTETRVASAVIFEGKINGKDVVLLQSGIGKVAAAIGTTALLQLAKPDLVINTGSAGGVAKGLKVGDIVISDETRYHDADVTAFGYEKGQLPANPAAFLSDKKLADLAQEIAEKQGQSVKRGLICSGDSFINSEDKITQIKADFPNVTGVEMEATAIAQVCYAFNVPFVVVRAISDGGDGKASISFEEFLPLAAKQSSALVLEMIDRL
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.