PharMolix/UniProtQA huggingface dataset:
Protein: RS9_STUS1
Sequence: MSATQNYGTGRRKTATARVFLRPGTGKISINNRELDNFFGRETARMVVRQPLELTETAEKFDIYVTVLGGGVSGQAGAIRHGITRALISYDESLRSPLRKAGFVTRDAREVERKKVGLRKARKRPQYSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: ASNC_ECOLI
Sequence: MENYLIDNLDRGILEALMGNARTAYAELAKQFGVSPGTIHVRVEKMKQAGIITGARIDVSPKQLGYDVGCFIGIILKSAKDYPSALAKLESLDEVTEAYYTTGHYSIFIKVMCRSIDALQHVLINKIQTIDEIQSTETLIVLQNPIMRTIKP
What is the function of this protein?
Activator of asnA transcription; autogenous regulator of its own transcription; and repressor of the expression of gidA at a post-transcriptional level.
What are the official names of this protein?
Regulatory protein AsnC.
Protein: QUEF_PSEAB
Sequence: MQHPAEHSPLGKTSEYVSSYTPSLLFPISRTAKWAELGLSAETLPYRGVDIWNCYELSWLTPAGKPVVAIGEFSIPADSPNIIESKSFKLYLNSLNQSAFDSREALRAVLQKDLSAAAGAPVGVRLRSLDEVAEEGIGRLPGRCIDELDIAVDGYEQPRPELLRCDAGRIVEEQLYSHLLKSNCPVTGQPDWGTLVVDYRGPALDPASLLAYLVSFRQHQDFHEQCVERIFLDLQRLLQPQALSVYARYVRRGGLDINPYRSLAEVAPDNRRLVRQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IN80D_MOUSE
Sequence: MYEGKHIHFSEVDNKPLCSYSPKLCKQRRLNGYAFCIRHVLEDKTAPFKQCEYVAKYNSQRCTNPIPKSEDRRYCNSHLQVLGFIPKKERKKKTDPVDEVKARHQMDAMAFSLTVPTLALKMPNGLDSMSLSPPGARVPLHYLDTELEDPFAFNEEDDDLKKGVTVRKKLQSKLAQNRQRQRETEILKVRQEHFSTPPTPPQQHTHLSPLSTSLKPPAPPQGSVCKSPQPQNTSLPMQGVAPTTHSIAQIRQASHKRPLPLLPSSRAPISDAPRTDRILMKAAAFSPHLSCISRLQRLVKLCTQKRQLDADLFPHLGLDWSEESGEELEDADQASPYQVAWSIRETLRHERHTSDDDDMESRSSRVTQLCTYFQQKYKHLCRLERAESRQKKCRHTFRKALLQAASKEPECTGQLIQELRRAACSRASLRQTKLKEVEPAACSGTVKGEQCTKQALPFTRHCFQHILLNRSQQLFSSCTAKFADGQQCSVPVFDITHQTPLCEEHAKKMDNFLRGDNSRKVQHQQQRKPRKKTKPPALTKKHKKKRRRGPRRPQKPIPPAVPQGNLSMPTSVSLPVEASQMRSPSTPELSADELPDDIANEITDIPHDLELNQEDFADVLPRLPDDLQDFDFFEGKNGDLLPTTEEAEELERALQAVTSLECLSTIGVLSQSDGVPVQGLSDRGMGVFSTGTDASGIQSLSREVNTDLGELLNGRIVHDSFSSLELDENLLHSAPLSSPPTALAGQIQGQFSAPASAGLTSATLLSQSALGERAFPGQFHGLHDGSHASQRPHPAQLLSKADDLITSRQQYSSDHSHSSPHGSHYDSEHVPSPYSDHITSPHTSYSGDNMAATFSAEMPIMAQHLLPTQLEVPLGGVVNPRTHWGNLPVNLGDPSAFSNLLGADGHLLSTSLSTPPTTSNSETTQPAFATVTPSSSSVLPGLPQTSFSGMGPSAELMASTSPKQQLPQFSAAFGHQLSSHSGIPKDLQPSHSSIAPPTGFTATGATATSTNNASPPFPSPN
What is the function of this protein?
Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.
What are the official names of this protein?
INO80 complex subunit D.
What is the protein family that this protein belongs to?
Belongs to the INO80D family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PROFX_OLEEU
Sequence: MSWQAYVDDHLMCDIEGHEDHRLTAAAIVGHDGSVWAQSATFPQFKPEEMNGIMTDFNEPGHLAPTGLHLGGTKYMVIQGEAGAVIRGKKGSGGITIKKTGQALVFGIYEEPVTPGQCNMVVERLGDYLLEQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity).
What are the official names of this protein?
Profilin-2, Pollen allergen Ole e 2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: COX1B_PARDE
Sequence: MADAAVHGHGDHHDTRGFFTRWFMSTNHKDIGILYLFTAGIVGLISVCFTVYMRMELQHPGVQYMCLEGARLIADASAECTPNGHLWNVMITYHGVLMMFFVVIPALFGGFGNYFMPLHIGAPDMAFPRLNNLSYWMYVCGVALGVASLLAPGGNDQMGSGVGWVLYPPLSTTEAGYSMDLAIFAVHVSGASSILGAINIITTFLNMRAPGMTLFKVPLFAWSVFITAWLILLSLPVLAGAITMLLMDRNFGTQFFDPAGGGDPVLYQHILWFFGHPEVYIIILPGFGIISHVISTFAKKPIFGYLPMVLAMAAIGILGFVVWAHHMYTAGMSLTQQAYFMLATMTIAVPTGIKVFSWIATMWGGSIEFKTPMLWAFGFLFLFTVGGVTGVVLSQAPLDRVYHDTYYVVAHFHYVMSLGAVFGIFAGVYYWIGKMSGRQYPEWAGQLHFWMMFIGSNLIFFPQHFLGRQGMPRRYIDYPVEFAYWNNISSIGAYISFASFLFFIGIVFYTLFAGKRVNVPNYWNEHADTLEWTLPSPPPEHTFETLPKREDWDRAHAH
What is the function of this protein?
Subunit I and II form the functional core of the enzyme complex.  Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).  This cytochrome c oxidase shows proton pump activity across the membrane in addition to the electron transfer.
What are the official names of this protein?
Cytochrome c oxidase subunit 1-beta, Cytochrome aa3 subunit 1-beta, Cytochrome c oxidase polypeptide I-beta.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: INT9_NEMVE
Sequence: MKLYCVGHSVSSPCLVLQFKQTNIMLDCGLDMSTVNQFTPLSLVNNEKFSQLKSWSSRELQEIEGFTAQNNLKEAGGRLFIDAEPEVCPPETGLIDFSMVDVILISNYHHMLALPFITEYSGFNGKIYATEPTIQIGRDLMLELVTFAERVPKRRNGNMWKNDNVIRCLPAPLNELANVKSWRVLYSKHDVKACISKIQAVSYSEKLDLCGILQLSAHSSGFCLGSSNWMLESEYEKISYLSPSSSFTTHPLPLNQTVLKNSDVLIITGVTEAPIDNPDAMLGEFCTHLASTLRAGGNVLVPCYPSGVLYDLFECLYTYLDNAKLGMVPIYFISPVADSSLAYSNIYGEWLCQSKQTKVYLPEPPFPHAELLKEARLKVFSNLHNGFSSSFKTPCVVFTGHPSLRYGDAVHFMEIWGKSGNNTVIFTEPDFPYLEALAPYQPLAMKTCYCPIDPRLNFAQANKLLKELQPRHLVMPESYSRPPVIHPHRTDLTIEDPGCSLTTFNHLDVAALPISRSFEKVVIANELSSCLHPQHVRPGVAVATLTGTLVTKDNKYTLQPLEFLVEPKAGSEGGDSSTNKGQLSRHLWGTVQLDDFVRSLKKRGITDVNVESSGGEHTIHLPNDDAMILLDRGSTHIITHGNEELRIRIRDALLECVPQF
What is the function of this protein?
Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.
What are the official names of this protein?
Integrator complex subunit 9 homolog.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS9 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: FUCO_DICDI
Sequence: MKMIIIFFILLILNLIKSQQYGPTWDQINSRPLPGWYDDVKFGIFIHFGIYSVPAFANGGYAEWYWWTLKNPSSDGGATQRYHEKEFGANFTYQDFVSRFDCRLFDANEWASIIEKSGAKYVVLTSKHHEGYTLWNSEQSWNWNSVETGPGIDIVGELTKSVKNMGLHMGLYHSLFEWFNPLYLADAETGKNPTTQVYVDEILMKQLKDIVTTYEPELIWADGDWMQLSNYWKSTEFLSWLYTNSSVKDTVIVNDRWGSECRDKNGGFYTGADHFNPYKLQSHKWENCATIGYSYGYDEYEQATDYQNATELIIDLVTTVACGGNFLLDVGPDAQGTIPNNMVDRLLEIGNWLSINSESIYGSSPWRVQNMTFNIWYTTNTTNGNVYAFVFELPDDGVLILSDPIGNNKTEATLLGLKGEKGVEVSLPIESTKPGITLNIPMVAPQDYPPYVYVFRLTDVE
What is the function of this protein?
Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
What are the official names of this protein?
Alpha-L-fucosidase, Alpha-L-fucoside fucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 29 family.
Protein: RS17_MYCLE
Sequence: MAAEAKTSAKAAPSATTAAPKGGAVKGGVSKDKGPKHTPSIPKVRGGRKMRIGYVVSDKMQKTIVVELEDRMRHPLYGKIIRTTKKVKAHDENSVAGIGDRVSLMETRPLSATKRWRLVEILEKAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: DARCH_STRAW
Sequence: MPTEETEPPVTAFMLVKTTPEWLALTVQERVDAFTTQVLPAIEARTSGVRSRFYDTEFYSARVTDVWVWEAEDHHAYQLLIDALRETPFWDRYFEVVDLLVGTENGYARTYGLEPVATITT
What are the official names of this protein?
Darcynin homolog.
What is the protein family that this protein belongs to?
Belongs to the darcynin family.
Protein: GREA_CLONN
Sequence: MSDSKQYIMTAEGVKKLEEELEYLKTVKRREITEKIKVALSYGDLSENSEYDEAKNEQAFVEGRIVQLENMLRNANVVDESEISLDAVSVGSIVKVKDYDFDEIIDFHIVGSAEADPMENKISNESPVGSALIGKKVGDVINVPVPDGISKFEILEIRV
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: RSMG_NEIMA
Sequence: MERKERLRAGIAAMGLDISETAQDRLLAYVDLLKKWNKTYNLTALRDEEKMIVHHLLDSLTLLPHIEGVQTMLDVGSGGGQPGIPAAVCRPDVQITLLDANTKKTAFLQQAVIELGLDNVRVVSGRVEAVSDVRADVVTSRAFAELADFVSWTAHLLKDGGYWAAMKGVYPQGEIGRLPQDVCVEKVQRLDVPGLDAERHIVILSKR
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVD_STRZP
Sequence: MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETPIVGVISTWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDIIADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKDIDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLPGSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNATLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLLANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDGAVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEMLSLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQDTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGKK
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: NFUA_STRMK
Sequence: MIQISDTAQTHFRKLIEREGVPGMGVRLSAVDPGTPRADARLEFAEPTDLLGDEWAVDCDGFTLYVDAGSVGWLDGAEIDIVAGSAGTQQLTIKAPRIKGEAPGDAASLVERVHWVVENEINPQLASHGGKVAVQEVSAEGVVLLRFGGGCQGCGMADVTLKQGIEKTLMGRVPGVTAVRDATDHDSGHAPYIPRGNAA
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: IHFA_GLAP5
Sequence: MALTKIEIAENLVERCGLDKRIAKQFVEDFFEEIRRSLESGEEVKLSGFGNFTVRDKKARPGRNPKTGEDVAVSARRVVVFKAGQKLRERVENAKVKA
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: C3H24_ARATH
Sequence: METSSIEINELPLATKTQTPPASVEPIPMETSSIDELPSSDSNATDNIEAVGEKRKRADEDEKTNLESSDTKITTPSPWWKTSLCSYFRREASCSHGNECKYAHGEAELRMKPDNTWDPTSERGKKAKAMKMSEHEEKEEDEVLFTEQMMESIDGDEGGGGSVSVVDLSLSKCLVHLPNKWQSDELKKFLGEQGVLYKSAKKRRGMIVGFVTFENAEQLQSGVEILDGKTVNSSNLKIADVLPRTFDKNDARKSVKSARDAVTPLAYLSYADQLEQKKTSIGQMLKKLARNARKACPNGNSLPQWVLTSRDRGGLACNLEGIIESPITNGYRNKCEFSVGLSLQGKPTVGFSLGSFCAGVTAVEEPVDCPNVSKIASQYASIFQKFIENSKFQVWNRFQHSGFWRQLTVREGRKPGVFSNDEDAITRIAEVMLMVQVCLTGSDEAEVATEFEELAKAFAEGARASSPTLPLTVLVVQNHSGISNVAPPDAPLQVLAIPISDNGTDQEQTTNVLTEARIHDHINNLRFSISPTAFFQVNTVTAEKLYSIAGDWADLGPDTLLFDVCCGTGTIGLTLAHRVGMVIGIEMNASAVADAERNATINGISNCKFICSKAEDVMSSLLKQYLDVTQMEEAKPLSNANDDLNKQIPSTEEMTNSEHVADQNLPPSNTQVEELQDNEQKDSSSLEPEKTTKPQFKNVVAIVDPPRSGLHPAVIKALRTHPRLKRLVYISCNPETLVANAIELCTPSFDEPDRGNKNYRGRKKIGIAALARHRAKSMPTSEAFRPVKAMAVDLFPHTDHCEMVMLLER
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 24, AtC3H24.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
Protein: RS17E_METAR
Sequence: MGSIRQTYIKSTTDALLRQYPNEFGSDFTANKAKVEQLASVQTKEVRNRIAGYVTRKMASKGRKK
What are the official names of this protein?
30S ribosomal protein S17e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS17 family.
Protein: MSCL_SODGM
Sequence: MSFLQKFRKFAMRGNVVDLAVGIIIGAAFGKIVSSLVANVIMPQLGLLIGGIDFKQFSWVLKPAQGDTPAVVMKYGIFLQNIFDFIIVAFAVFCIIKLINRNASQRGGKTRRAVQTECGRDAAYRDPRSLETTKQRHGAGYNDD
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: QUEC_BAUCH
Sequence: MPHNQQIKKTVVVFSGGQDSTTCLIQALTQYDQVYCITFDYGQRHRAEICIARRLTITLGAYDHQIIDTSALNVLAASSLTRENIIVPLAEKNHMNSSLSTFVPGRNIVFLTLAAIYAYQVKAEVIITGVCETDFSGYPDCREKFIQALNKAVNLGMAYNIHFISPLMWLNKAETWALADYYQKLDLVCNETLTCYNGIQGKGCGFCTSCSLRARGLETYKQQPKLTMSSLKAKTGLP
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: DEF_LATSS
Sequence: MILMKDIIREGNPTLREIAQPVSFPLSDEDRQLAADMMTFLENSQDPEIAAKYQLRAGVGLAAPQVDVSKQMSAVLVPGPEGEAPILKDVIINPKIISHSVQDAALAEGEGCLSVDREVPGYVPRHDRITLRYQDVEGVSHKIRLKNYPAIVCQHEIDHLNGILFFDHINKENPFAAPDDMIILE
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: LRIG2_MOUSE
Sequence: MAAAPRGIWEQRRLGCGLGPLARLLILAQALRLLPAARAGLCPAPCACRLPLLDCSRRKLPAPSWRALSGPLPSDISSLDLSHNRLSNWNNTLESQTLQEVKMNYNELTEIPYFGEPTPNITLLSLVHNLIPEINAEAFELYSALESLDLSSNIISEIKTSSFPRMSLKYLNLSNNRISTLEAGCFDNLSDSLLVVKLNRNRISMIPPKVFKLPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTGVNKGWLYGLRMLQQLYMSQNAIEKISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNDISWAIEDASEAFSGLKSLTKLILQGNRIKSVTQKAFIGLESLEYLDLNNNAIMSIQENAFSQTHLKGLVLNTSSLLCDCHLKWLLQWLVDNNFHHSVNVSCAHPEWLAGQSILNVDLKDFVCDDFLKPQIRTHPESTIALRGVNVTLTCTAVSSSDSPMSTIWRKDSEILYDVDIENFVRYRQQDGEALEYTSVLRLFSVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNEMPSFLKTPMDLTIRTGAMARLECAAEGHPTPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANVKIEDMGIYSCMAQNIAGGLSANASLTVLETPSFIRPLEDKTVTRGETAVLQCIAGGSPAPRLNWTKDDGPLLVTERHFFAAANQLLIIVDAGLEDAGKYTCLMSNTLGTERGHIYLNVISSPNCDSSQSSIGHEDDGWTTVGIVIIVVVCCVVGTSLIWVIVIYHMRRKNEDYSITNTEELNLPADIPSYLSSQGTLSEPQEGYSNSEAGSHQQLMPPANGYTHRGTDGGAGTRVICSDCYDNANIYSRTREYCPYTYIAEEDVLDQALSSLMVQMPKETFLSHPPQDAANLESLIPSAEREPAAFPTNHERMTENLPFSQRSSEIFQRPLWNMNRELGLLPFSQQPVLESPELTERDPNCSSPVTCRRLHDHAFDFSRTRIIQDGTEGT
What are the official names of this protein?
Leucine-rich repeats and immunoglobulin-like domains protein 2, LIG-2.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cytoplasm.
Protein: PB1F2_I83A4
Sequence: MEQEQDIPWTQSAEHTNIQKRESGQQTQRLEHPSLTRLMDHYQRTMSQADMHRQIVSWRQWLSLKNPTQGSLKTRVLKRWKLFSKQGWTN
What is the function of this protein?
Plays an important role in promoting lung pathology in both primary viral infection and secondary bacterial infection.  Promotes alteration of mitochondrial morphology, dissipation of mitochondrial membrane potential, and cell death.  Alternatively, inhibits the production of interferon in the infected cell at the level of host mitochondrial antiviral signaling MAVS.  Its level of expression differs greatly depending on which cell type is infected, in a manner that is independent of the levels of expression of other viral proteins.  Monocytic cells are more affected than epithelial cells.  Seems to disable virus-infected monocytes or other host innate immune cells.  During early stage of infection, predisposes the mitochondria to permeability transition through interaction with host SLC25A6/ANT3 and VDAC1.  These proteins participate in the formation of the permeability transition pore complex (PTPC) responsible of the release of mitochondrial products that triggers apoptosis.
What are the official names of this protein?
Protein PB1-F2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB1-F2 family.
What are the subcellular locations of this protein?
Host mitochondrion inner membrane. Host nucleus. Host cytoplasm, host cytosol. Note=Inner mitochondrial membrane in most cells types. Otherwise is detected in the nucleus and cytosol.
Protein: WRK57_ARATH
Sequence: MNDPDNPDLSNDDSAWRELTLTAQDSDFFDRDTSNILSDFGWNLHHSSDHPHSLRFDSDLTQTTGVKPTTVTSSCSSSAAVSVAVTSTNNNPSATSSSSEDPAENSTASAEKTPPPETPVKEKKKAQKRIRQPRFAFMTKSDVDNLEDGYRWRKYGQKAVKNSPFPRSYYRCTNSRCTVKKRVERSSDDPSIVITTYEGQHCHQTIGFPRGGILTAHDPHSFTSHHHLPPPLPNPYYYQELLHQLHRDNNAPSPRLPRPTTEDTPAVSTPSEEGLLGDIVPQTMRNP
What is the function of this protein?
Transcription factor.  Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity).
What are the official names of this protein?
Probable WRKY transcription factor 57, WRKY DNA-binding protein 57.
What is the protein family that this protein belongs to?
Belongs to the WRKY group II-c family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARLY_PARMW
Sequence: MAGGVTGGAAGAWSDRFEQGLHPFVEAFNASIGFDLTLLQEDLDGSIAHARMLASCGVIAEEEAVQLVDGLELIRTEAADGRFNPGLEDEDVHFAVERRLIALVGSVGKKLHTGRSRNDQVGTDLRLWLRRRLDEIDGDLQRLQRALLDQADRHQSTMIPGYTHLQRAQPLCLAHHLLAYIEMLQRDRQRLGDVRGRVNICPLGAAALAGTPVPIDRRRTAEDLGFTAIYANSLDAVSDRDFCVEFSAAASLVMAHLSRLAEEVIAWASEEFGFVRLSDRCATGSSLMPQKKNPDVPELVRGKCGRVFGHLQGLLTMIKGLPLAYNKDFQEDKEALFDAYRTTRDCVEAMAILFEEGLEFRIDRLNQAVESDFSNATDVADYLVARGVPFREAYQLVGAVVRRCLEQDCLLRELSLEQWKEIHPAFEADLHEALAPRAVVSARRSEGGTGFDRVHEQVMLWQERLKESAVG
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAA_MYCSM
Sequence: MTADPDPPFVAVWNSVVAELNGDVNGDRQGDPSLPVLTPQQRAWLKLVKPLVIAEGFALLSVPTPFVQNEIERHLREPIVTALSRKLGQRVELGVRIATPTDEPEDAPDSFADSPAPASVPAGPADADEIDDDRDARVNAQESWPKYFSRPEPDTSSDDSNAVNLNRRYTFDTFVIGASNRFAHAATLAIAEAPARAYNPLFIWGESGLGKTHLLHAAGNYAQRLFPGMRVKYVSTEEFTNDFINSLRDDRKASFKRSYRDIDILLVDDIQFIEGKEGIQEEFFHTFNTLHNSNKQIVISSDRPPKQLATLEDRLRTRFEWGLITDVQPPELETRIAILRKKAQMDRLDVPDDVLELIASSIERNIRELEGALIRVTAFASLNKTRIDRSLAEVVLRDLIADATTMQISTAAIMAVTAEYFETTVEELRGPGKTRALAQSRQIAMYLCRELTDLSLPKIGQAFGRDHTTVMYAEKKIRGEMAERREVFDHVKELTTRIRQRAKR
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids (By similarity).
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACDH4_BURL3
Sequence: MMKDLDKLAVAIIGSGNIGTDLMIKVLRHAKHLDVAAMVGIDPASDGLARAARLGVPTTAGGIDGLVAMPGFADVRIAFDATSAGAHARHAEVLGRHGVQVIDLTPAAIGPFVVPVVNLFEHLDAPNLNMVTCGGQATIPIVHAVSRVAPVHYAEIVASISSRSAGPGTRANIDEFTETTSKAIETVGGAARGKAIIVLNPAEPPLMMRDTVYCLTDEDADTAAIEHSIRTMVDAVASYVPGYRLKQAVQFDRYTAAQPLAFDAGERRAGLKVSVFLEVEGAAHYLPSYAGNLDIMTSAALAAAEQIAASRVAA
What are the official names of this protein?
Acetaldehyde dehydrogenase 4, Acetaldehyde dehydrogenase [acetylating] 4.
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: SFGH2_SHIF8
Sequence: MEMLEEHRCFEGWQQRWRHDSSTLNCPMTFSIFLPPPRDHTPPPVLYWLSGLTCNDENFTTKAGAQRVAAELGIVLVMPDTSPRGEKVANDDGYDLGQGAGFYLNATQPPWATHYRMYDYLRDELPALVQSQFNVSDRCAISGHSMGGHGALIMALKNPGKYTSVSAFAPIVNPCSVPWGIKAFSTYLGEDKNAWLEWDSCALMYASNAQDAIPTLIDQGDNDQFLADQLQPAVLAEAARQKAWPMTLRIQPGYDHSYYFIASFIEDHLRFHAQYLLK
What is the function of this protein?
Serine hydrolase involved in the detoxification of formaldehyde.  Hydrolyzes S-formylglutathione to glutathione and formate (By similarity).
What are the official names of this protein?
S-formylglutathione hydrolase YeiG, FGH.
What is the protein family that this protein belongs to?
Belongs to the esterase D family.
Protein: CDSH_SCHPO
Sequence: MARKRTNKRNNSDKENGNVGVVQNKDSASSKTTEPARLTKHKSLARKPSQNFITRTIWTFLLLGIFFTALAMGHFWVVLLVTIVQIGVYKEVIAIASVPSREKDLPWTRFINWYFLMTTLYYAYGESIYAYFHHLFIMDSFMLPLVLHHRFISFMLYIIGFVLFVASLKKGNYKFQFSQFCWTHMTLLLVVGQSHFMINNLFEGLFWFFVPVCYVVCNDVFAYLCGKMFGKHPLIQVSPKKTVEGFLGGWICTVVIGSLISYVLMHFKYFICPTRDLSTSAFSGLNCTPNSVFLPHTYTIPAVFVDTFRLPETITLAPIYFHLAIFATFSSLIAPFGGFFASGLKRAFKIKDFGASIPGHGGLTDRMDCQFLNGVFVYMYFQSFIAEKSTSVADLLDTAVYSLTTTQQVQLVEDLQNYLISHGKTSVQAICSKLLQNSK
What is the function of this protein?
Supplies CDP-diacylglycerol, which may play an important role as both a precursor to phosphoinositide biosynthesis in the plasma membrane and as a negative effector of phosphatidylinositol 4-kinase activity, thereby exerting an effect on cell proliferation via a lipid-dependent signal transduction cascade.
What are the official names of this protein?
Putative phosphatidate cytidylyltransferase, CDP-DAG synthase, CDP-DG synthase, CDP-diacylglycerol synthase, CDS, CDP-diglyceride pyrophosphorylase, CDP-diglyceride synthase, CTP:phosphatidate cytidylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CDS family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RS19_LISW6
Sequence: MGRSLKKGPFVDDHLMKKVEAAAESEKKQVIKTWSRRSTIFPTFVGQTIAVYDGRKHVPVYVQEDMVGHKLGEFAPTRTYRGHAGDDKKTKR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.