PharMolix/UniProtQA huggingface dataset:
Protein: DNAJ_BORBU
Sequence: MKKDYYEILGLSKGASKDEIKKAYRKIAIKYHPDRNQGNEEAASIFKEATQAYEILIDDNKKAKYDRFGHSAFEGGGFEGFSGGFSGFSDIFEDFGDIFDSFFTGNKGQERNRKHAKGEDLGYNIEISLENAYFGYKNNINITRQMLCDSCLGKKSEKGTSPSICNMCNGSGRVVQGGGFFRVTTTCSKCYGEGKIISNPCKSCKGKGSLTKQETIQLNIPPGIDNNQQIKMKGKGNVNPDNQEYGDLYVKILIRSHKVFKRNGKDLYAMLPISFTQAALGKEVKIKTIASKEIKIHIPKGINNEEQILIKNAGMPILQTEKFGNLILITKIKTPKNLNSNAIKLFENLGKELKDGDEIDLLKA
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLIP1_RAT
Sequence: MRSRNQGGESSSNGHVSCPKSSIISSDGGKGPSEDAKKNKANRKEEDVMASGTIKRHLKPSGESEKKTKKSVELSKEDLIQLLSIMEGELQAREDVIHMLRTEKTKPEVLEAHYGSAEPEKVLRVLHRDAILAQEKSIGEDVYEKPISELDRLEEKQKETYRRMLEQLLLAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAVTYKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEEELQELREKIAKGECGNSSLMAEVESLRKRVLEMEGKDEEITKTEAQCRELKKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSRSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKEYSLTKERDELMGKLRSEEERSCELSCSVDLLKKRLDGIEEVEREINRGRSCKGSEFTCPEDNKIRELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQMAKHKAIEKGEAVSQEAELRHRFRLEEAKSRDLQAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFMEEETKNKNMGREVLNLTKELELSKRYSRALRPSGNGRRMVDVPVASTGVQTEAVCGDAAEEETPAVFIRKSFQEENHIMSNLRQVGLKKPMERSSVLDRYPPAANELTMRKSWIPWMRKRENGPSTPQEKGPRPNQGAGHPGELVLAPKQGQPLHIRVTPDHENSTATLEITSPTSEEFFSSTTVIPTLGNQKPRITIIPSPNVMSQKPKSADPTLGPERAMSPVTITTISREKSPEGGRSAFADRPASPIQIMTVSTSAAPTEIAVSPESQEVPMGRTILKVTPEKQTVPAPVRKYNSNANIITTEDNKIHIHLGSQFKRSPGPAAEGVSPVITVRPVNVTAEKEVSTGTVLRSPRNHLSSRPGASKVTSTITITPVTTSSTRGTQSVSGQDGSSQRPTPTRIPMSKGMKAGKPVVAASGAGNLTKFQPRAETQSMKIELKKSAASSTASLGGGKG
What is the function of this protein?
By acting through a filamin-A/F-actin axis, it controls the start of neocortical cell migration from the ventricular zone.  May be able to induce the degradation of Filamin A.
What are the official names of this protein?
Filamin-A-interacting protein 1, FILIP.
What is the protein family that this protein belongs to?
Belongs to the FILIP1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. SUBCELLULAR LOCATION: [Isoform 1]: Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, stress fiber. Note=Localized along actin stress fibers, except at their ends, suggesting colocalization with F-actin (fiber-like). SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm, cytoskeleton. Note=Punctate distribution in the cytoplasm distinct from that of F-actin.
Protein: BDNF_FELCA
Sequence: MTILFLTMVISYFGCMKAAPMKEANVRGQGSLAYPGVRTHGTLESVNGPKAGSRRLTSLADTFEHVIEELLDEDQKGRPNEENSKDADLYTSRVMLSSQVPLEPPLLFLLEEYKNYLDAANMSVRVRRHSDPARRGELSVCDGISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR
What is the function of this protein?
Important signaling molecule that activates signaling cascades downstream of NTRK2.  Activates signaling cascades via the heterodimeric receptor formed by NGFR and SORCS2.  Signaling via NGFR and SORCS2 plays a role in synaptic plasticity and long-term depression (LTD).  Binding to NGFR and SORCS2 promotes neuronal apoptosis.  Promotes neuronal growth cone collapse.
What are the official names of this protein?
Brain-derived neurotrophic factor, BDNF.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted. SUBCELLULAR LOCATION: [BDNF precursor form]: Secreted. Note=A proportion of BDNF is secreted as immature precursor (proBDNF).
Protein: RL11_STRCO
Sequence: MPPKKKKVTGLIKLQIQAGAANPAPPVGPALGQHGVNIMEFCKAYNAATESQRGWVIPVEITVYEDRSFTFITKTPPAAKMILKAAGVEKGSGEPHKTKVAKITRDQVREIATTKMPDLNANDLDQAEKIIAGTARSMGVTVEG
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RPOC_BRUC2
Sequence: MNQEVMNLFNPQAPAQTFDSIRISIASPEKILSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMKYKGIICEKCGVEVTLSRVRRERMGHIELAAPVAHIWFLKSLPSRIGTLLDMTLKDIERVLYFENYIVTEPGLTSLKEHQLLSEEEYMIAVDEFGEDQFTALIGAEAIYELLASMELEKIAADLRVDLAETTSDLKQKKLMKRLKIVENFLESGNRPEWMIMKIVPVIPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPGIIIRNEKRMLQEAVDALFDNGRRGRVITGANKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVTGPELKLHQCGLPKKMALELFKPFIYARLDAKGYSSTVKQAKKLVEKERPEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPTLIEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSLEAQLEARVLMMSTNNILHPANGAPIIVPSQDMVLGLYYLSIVAEKEPGEGMIFADMGELQHALENKVVTLHTKIKSRFKTVDAEGNPVSKIYDTTPGRMIMGELLPKNVNVPFDICNQEMTKKNISKMIDHVYRHCGQKETVIFCDRIMQLGFAHACRAGISFGKDDMVIPESKAKIVAETEALTTEYEQQYNDGLITQGEKYNKVVDAWGKATDKITEEMMARLKAVEFDPVTGRQKQMNSVYMMSHSGARGSVNQMRQLGGMRGLMAKPSGEIIETPIISNFKEGLTVNEYFNSTHGARKGLADTALKTANSGYLTRRLVDVAQDAIISEVDCGAEIGLTMQPIVDAGQIVASIGQRVLGRTALDPILHPVTGEVIVEAGRMIEEKDVEIIEKAGIQSIRIRSALTCETRDGVCAKCYGRDLARGTPVNQGEAVGVIAAQSIGEPGTQLTMRTFHLGGTAQVVDSSYLEASYEGTVKLRNRNVVRNSDGNLVVMGRNMAVLILDATGKERAVHRVTYGSRLFVDEGDTVKRGQRIAEWDPYTRPIMTEVEGYVEFEDLVDGLSVSETADESTGITKRVVIDWRSTPRGSDLKPAMVIKDKAGKILKLSKGGDARFLLSVESILSVEPGAHVKAGDVIARLPMESAKTKDITGGLPRVAELFEARRPKDHAIIAEIDGTVRFGRDYKNKRRIIIEPNDDTIEPVEYLIPKGKPFHLQDGDVIEKGEYILDGNPAPHDILAIKGVEALASYLVNEIQEVYRLQGVLINDKHIEVIVRQMLQKVEITESGDTGYIPGDHVDRIELEEINERLIEEGKKPGSGNPVLLGITKASLQTPSFISAASFQETTRVLTEAAVAGKMDTLQGLKENVIVGRLIPAGTGGMTNQIRRIATARDELIIDERRKTSGSAEANAMLVDMTNNAAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: DYH12_BOVIN
Sequence: MELLLQKGANALGQASDSSSILLEAASGGNPDSVTLLLEYGADANVPKNSGHLPIHVAADRGHLLALKTLVPVTDFAAIKRSGISPIHCAAAGAHPKCLELLIQAGFDVNFMLDQRIRKHYDDHRKSALYFAVSNGDLSSVKLLLSAGAMPNQDPVNCLQIALRMGNYELVSLLLRHGANVNYFCRVNPLHFPSALQYTLKDEVMLRMLLNYGYDTELCFDCPHGDKVHRFSASEGWTSTVIKDTMFCEVITLSWLQHLSGKVVRVMLDYVDQVRICSKLKAVLQKQGLWSEIHFILTNPRSLKHLCRLKIRKCMGRLRLRCPVFMSFLPLPSRLKAYVLYKEYDLYEQGIFTGTW
What is the function of this protein?
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
Dynein axonemal heavy chain 12, Ankyrin repeat and SOCS box protein 14, ASB-14, Axonemal beta dynein heavy chain 12, Ciliary dynein heavy chain 12.
What is the protein family that this protein belongs to?
Belongs to the dynein heavy chain family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme.
Protein: SYI_MYCS5
Sequence: MSLDFKKTLNMPSTKFDMKANLVEKEPLFRKKWLEDDIYQKVLKNNANNERFVVHDGPPYANGDIHVGHALNKILKDIIVRYKSLQGYYSPFVPGWDTHGLPIEHKMLTESKLDRDQITVELLRKKSRNYALKQIEHQKKQFQKLQLFSDFSKIYITLDKSYEAKQLKVFKKLALDGLVYKGLKPIYWSPSSQSALAEAEVEYETVTTNSIYVSFDVTKSTFNKVPVGSKLVVWTTTPWTLIANAAVAISFDITYLTVKYQDSLYVVAKNLFYNDLLEKFQWENYEVVDEFLGKEMPRNSIWYKAPLLDFDAPVIATNYVLEDSGTGLVHSAPLFGEDDFSLTFDNDLKLIMHISDTGHIENSQTKYDSLFYEEANKEIIKDLAEKVVHVYTYSHSYPHDWRTKKPIIYRATPQWFVSIDKVRSKIVSELQNKVKTFPEWSKNRMISMIENRGDWTISRQRTWGVPIIIFYDENEKPVINEEIFDHVIDLVANHGTDIWFSSTVDELLPEKYRNRNWTKENDIMDVWFDSGVSSIAVDIDGGKTTLPFDVYLEGNDQFRGWFNSSVINAVAYAGVSPYINLVSHGFALDGQGKKMSKSRNNVVDPLDVIKKYGADILRLWVANSEYSSDVHISESILVQNSEIYRKIRNTVKFLLGNLNNFKYDKDLKLTSIHHYINEELKSVKKEVLENYDKFRFINVIKVLNRYVIDLSSFYFSVTKDILYIRKENDEERQMVLKNFYEILDFLMLALAPIIPTTADEMYSYFNKENKKESLFLERLEKAGDVSFDEKVLEQFKEFFELRDQVNILIENQIQNKVIKRSNELELVLPETASEFLKSLDLKTLLMVSKISYGKTLQVVKFESEKCKRCWNHFASLNKEYEICDLCFSVLKDTLANA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IDI2_THEVO
Sequence: MIEKRKEEHIRIAENENVSAFHNYWDDVYLMHEADPEVNYDDIDTGVDFLGKHLGFPMVISSMTGGAEIAKKINYNLATVAEKYQLAMGVGSMRAAIVNRSLSDTYSVINERNVPIKIANIGAPQLVPQGKEAIDEKDIAYIYDLIKADFLAVHFNFLQEMVQPEGDRNAEGVIKRIKELSGSFNIIAKETGSGFSKATAQRLADAGVKAIEVSGLSGTTFAAVEYYRAKNEGNAEKMRIGETFWNWGIPSPASVYYCSDVLPVIGSGGLRNGLDLAKAISLGASLGGFARTLLKDADQSVEAVSRNVEMIEREFKVAMFLTGNKNVYELRKTKKVIGEPLKEWMEV
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CWP06_DAUCA
Sequence: SEVGALVFQPKTRF
What are the official names of this protein?
30 kDa cell wall protein.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: NUSB_CLAMS
Sequence: MSARTKARKRALDVLYVADIRGESIPATLAVEQQRAAAEPDRQASWAYAREIAEGFVEHQDEIDELIETYSVNWTLARMPAVDRAILRIGIWEILFNADVPDGVAISESVDLASSLSTDESASFVNGMLARIAAAQA
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: Y3200_MYCTO
Sequence: MCSGPKQGLTLPASVDLEKETVITGRVVDGDGQAVGGAFVRLLDSSDEFTAEVVASATGDFRFFAAPGSWTLRALSAAGNGDAVVQPSGAGIHEVDVKIT
What are the official names of this protein?
Uncharacterized protein MT3200.
Protein: SYI_RICBR
Sequence: MTNTKYYPEVSSNADFATIEKEILKFWQDNNIFQKSIDIREGDAEFIFYDGPPFANGLPHYGHLLTGFIKDVYARYQTVRGKKVERRFGWDCHGLPAEMQSEKELGISGHLAITNFGIEKFNAHCRDSVMKYAGEWEQYVTRQARWVDFKNSYKTMDKNFMESVLWAFKELYNKGLLYESMRVMPYSWACETPLSNFETRLDNSYRERADKAVTVSFVLCHPVSKSTLDVIPWLDHGIQKTINNDSANCSMDPVDKPRYDTENFLGITANYKEYRILAWTTTTWTLPSNLALAVGSDIDYALVPKGDVCYIIAASSVSKYAKELELKGDEQFTIIKGSELQGLSYKPLFDYFKNHPNSFKIFAGDFVVEGDGTGVVHMAPGFGEDDQILCESKGIKLVCPVDNSGKFTKEIPDLEGLQVFDANDKIIIKLKEQGNWLKTEQYIHNYPHCWRTDTPLIYKAVPSWYVKVTEFKDRMVELNQQINWIPTHVKDNLFGKWLENARDWSISRNRFWGTPLPVWKSDDPKYPRIDVYGSIEELEKDFGVKITDLHRPFIDELTRANPDDPTGKSTMRRIEDVFDCWFESGSMPYGQAHYPFENKQWFEEHFPADFIVEYSAQTRGWFYTLMVLSTALFDRPPFLNCICHGVILDATGQKLSKRLNNYADPLELFDKYGSDALRVTMLSSNVVKGQELLIDKDGKMVFDTLRLFIKPIWNAYHFFTMYVNADHIKGELNFTSENVLDVYILSKLKIAVEKIKESLDSFDTGTAYHAVSEFFEVLNNWYIRRSRARFWKSEKDADKQSAYNTLYTCLETMAIAMSSLVPLISEAIYLGLYCHPRKSGDPEKPECLDSRLCGNDNLSVHLCDYPDLSKFKINSELVDTMDTVLDICSHSLFIRSSENARVRQPLSSITIISKNNDKLKSFEDLIKDEINVKSVIYRDDLENYAVKKLSINFPLLGKRLPAKMKDIIAASKKNEWEVTSGSLIICNETLNSDEYKLILEPHSHIKGASSFAHNSSLLILDLELTPELIDEGIARDIVRFIQQARKNADFAITDRILIDINLPKITDIYGEFIKEQTLGEFAKDFIPDHISEIELDNHKLQLKIKKVN
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PARD_VIBCH
Sequence: MAKNTSITLGEHFDGFITSQIQSGRYGSASEVIRSALRLLENQETKLQSLRQLLIEGEQSGDADYDLDSFINELDSENIR
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system.  Neutralizes the effect of toxin ParE (By similarity).
What are the official names of this protein?
Antitoxin ParD.
What is the protein family that this protein belongs to?
Belongs to the ParD antitoxin family.
Protein: VP4_LBVAV
Sequence: MDEENVDITEDELSVISDLELDSITRVVGTNEIKTYEDYKLEEANYLKVLDIIKKFSTSDTCECYRCELFERGDIGKFLTRSEFSKLAVLYWERCGRPRNSEALEAFIGRHICIRCAASILLSHHPVIAMRADMRLREIYIENGDKPASSSGTLFSAKGKGPRI
What are the official names of this protein?
Protein 4.
Protein: QUEF_BURCM
Sequence: MNPEHSPLGKATVYAAQYDASLLFPIPRAGAREQLGITSALPFFGTDIWNAYELSWLNARGKPQVAVATFYVPAESPNIVESKSFKLYLGSFAQSKFDSLDAVRDTLKRDVSAACGASVSVQLVSPHDFGKLQMEELDGLSLDRLDLDTDVYEPDPSLLSAAQDEAPVEETLVSDLLRSNCPVTGQPDWGSVQIHYVGPQIDHAGLLRYIISFRNHTGFHEQCVERIFLDILHACKPLKLAVYARYTRRGGLDINPFRTNYNQPMPDNARTARQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP25_CANTT
Sequence: MIARGRVLNDTALKSKAMFGFTVLKLVSRHIHHTPIIFQEKKDAQVDLGVPWYLRQENSPPVEEIKKVEIPELPESAPGSLSELVHLIAEEYGIVDVEVFDLATLPEDHPKSVDVQSYDKYIILGTGKSEKHLYKAAYELKQYIKHHHDCMPVIEGMVSNSIGKVARRRLAKRVSRGPPATHSTYGIGANTWVSCDTGVDGITIHMLTKERRQEMNLEQLYSDAPDYESNRYTNNIDDDDIFYGIKRGFHTSTRVFNKADQLKVVYDELLENGKTKSLAKFKAQFDNLFSGASVEEYNRKVDFYKVISLMDEQLVTAEQVECIFKDKYSSLLLAQEQGIDWHMEVTNDIIKYMELLADVGDQYTPAQKLNKLSEFVSDMTNFTGDSVQLFSIDKFNALLWNLTTKSTFNQLDSAGIREVINTKGKFEPVVGKVEQDAKIERCVKELTRRSLPKEVFPLWFREQMMYTYGQTGAWDKFWKEFQSLVQSIGSSKDRVYFWVTTLIFLSKVNNRDALRTYFTKYWSSPSGYSFLKDFEKNDNRFNSDNERIVFKRTVQDIQNSYGSSPWKDEAVEFVENL
What is the function of this protein?
Probable mitochondrial mRNA stabilization factor.
What are the official names of this protein?
ATPase synthesis protein 25, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ATP25 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: MSRA_MYCTO
Sequence: MTSNQKAILAGGCFWGLQDLIRNQPGVVSTRVGYSGGNIPNATYRNHGTHAEAVEIIFDPTVTDYRTLLEFFFQIHDPTTKDRQGNDRGTSYRSAIFYFDEQQKRIALDTIADVEASGLWPGKVVTEVSPAGDFWEAEPEHQDYLQRYPNGYTCHFVRPGWRLPRRTAESALRASLSPELGT
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: TUS_SALA4
Sequence: MSRYDLVERLNGTFRQIEQHLAALTDNLQQHSLLIARVFSLPQVTKEAEHAPLDTIEVTQHLGKEAEALALRHYRHLFIQQQSENRSSKAAVRLPGVLCYQVDNAIQLDLENQIQRINQLKTTFEQMVTVESGLPSAARFEWVHRHLPGLITLNAYRTLTLINNPATIRFGWANKHIIKNLSRDEVLSQLKKSLASPRSVPPWTREQWQFKLEREYQDIAALPQQARLKIKRPVKVQPIARIWYKGQQKQVQHACPTPIIALINTDNGAGVPDIGGLENYDADNIQHRFKPQAQPLRLIIPRLHLYVAD
What is the function of this protein?
Trans-acting protein required for termination of DNA replication.  Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks.  The termination efficiency will be affected by the affinity of this protein for the terminator sequence.
What are the official names of this protein?
DNA replication terminus site-binding protein, Ter-binding protein.
What is the protein family that this protein belongs to?
Belongs to the Tus family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR1_STAAW
Sequence: MFNYSGLNEECGVFGIWNHPEAAQLTYMGLHSLQHRGQEGAGIVVSDQNELKGERGLGLLTEAIKDDQMERLKGYQHAIGHVRYATSGNKGIENIQPFLYHFYDMSVGICHNGNLINAKSLRQNLEKQGAIFHSSSDTEVIMHLIRRSKAPTFEEALKESLRKVKGGFTFAILTKDALYGAVDPNAIRPLVVGKMKDGTYILASETCAIDVLGAEFVQDIHAGEYVVINDKGITVKSYTHHTTTAISAMEYIYFARPDSTIAGKNVHAVRKASGKKLAQESPVNADMVIGVPNSSLSAASGYAEEIGLPYEMGLVKNQYVARTFIQPTQELREQGVRVKLSAVKDIVDGKNIILVDDSIVRGTTIRRIVKMLKDSGANKVHVRIASPEFMFPSFYGIDVSTTAELISASKSPEEIKDYIGADSLAYLSVDGLIESIGLDYDAPYSGLCVESFTGDYPAGLYDYEANYKAHLSHRQKQYISKNKHFFDSEGNLNV
What is the function of this protein?
Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
What are the official names of this protein?
Amidophosphoribosyltransferase, ATase, Glutamine phosphoribosylpyrophosphate amidotransferase, GPATase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
Protein: E1124_IXORI
Sequence: MAVNVFTILQLAVFAAIVLNVNLHSVSADSKGTSDSQDSTKSIKVDFCETNCTKTDGGWTGCTGDCICVSVGDSIEGRCMDFG
What is the function of this protein?
Salivary chemokine-binding protein which binds to host chemokines CXCL1, CXCL2, CXCL3, CXCL5, CXCL6, CXCL12 and CXCL13.
What are the official names of this protein?
Evasin P1124.
What are the subcellular locations of this protein?
Secreted.
Protein: STX4_SCOAN
Sequence: AKEKEVTFQ
What are the official names of this protein?
Scolopendra 5887.74 Da toxin.
What is the protein family that this protein belongs to?
Belongs to the scolopendra toxin 4 family.
What are the subcellular locations of this protein?
Secreted.
Protein: MSRA_STRPB
Sequence: MERAIFAGGCFWCMVQPFEEQAGILSVRSGYTGGHLPNPSYEQVCAKTTGHTEAVEIIFDPKQIAYKDLVELYWAQTDPTDAFGQFEDRGDNYRPVIYYTTERQKEIAEQSKANLQASGRFDQPIVTTIEPAEPFYLAEDYHQGFYKKNPKRYAQSSAIRHQFLEENWS
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: INIB_MYCTU
Sequence: MTSLIDYILSLFRSEDAARSFVAAPGRAMTSAGLIDIAPHQISSVAANVVPGLNLGAGDPMSGLRQAVAARHGFAQDVANVGFAGDAGAGVASVITTDVGAGLASGLGAGFLGQGGLALAASSGGFGGQVGLAAQVGLGFTAVIEAEVGAQVGAGLGIGTGLGAQAGMGFGGGVGLGLGGQAGGVIGGSAAGAIGAGVGGRLGGNGQIGVAGQGAVGAGVGAGVGGQAGIASQIGVSAGGGLGGVGNVSGLTGVSSNAVLASNASGQAGLIASEGAALNGAAMPHLSGPLAGVGVGGQAGAAGGAGLGFGAVGHPTPQPAALGAAGVVAKTEAAAGVVGGVGGATAAGVGGAHGDILGHEGAALGSVDTVNAGVTPVEHGLVLPSGPLIHGGTGGYGGMNPPVTDAPAPQVPARAQPMTTAAEHTPAVTQPQHTPVEPPVHDKPPSHSVFDVGHEPPVTHTPPAPIELPSYGLFGLPGF
What are the official names of this protein?
Isoniazid-induced protein IniB.
Protein: NMBR_MOUSE
Sequence: MPPRSLSNLSFPTEANESELVPEVWEKDFLPDSDGTTAELVIRCVIPSLYLIIISVGLLGNIMLVKIFLTNSAMRNVPNIFISNLAAGDLLLLLTCVPVDASRYFFDEWVFGKLGCKLIPAIQLTSVGVSVFTLTALSADRYRAIVNPMDMQTSGVLLWTSLKAVGIWVVSVLLAVPEAVFSEVARIGSLDNSSFTACIPYPQTDELHPKIHSVLIFLVYFLIPLVIISIYYYHIAKTLIKSAHNLPGEYNEHTKKQMETRKRLAKIVLVFVGCFVFCWFPNHVLYLYRSFNYKEIDPSLGHMIVTLVARVLSFSNSCVNPFALYLLSESFRKHFNSQLCCGRKSYPERSTSYLLSSSAVRMTSLKSNTKNVVTNSVLLNGHSTKQEIAL
What is the function of this protein?
Receptor for neuromedin-B (By similarity).  Contributes to the maintenance of basal sigh rate through signaling in the pre-Botzinger complex, a cluster of several thousand neurons in the ventrolateral medulla responsible for inspiration during respiratory activity (PubMed:26855425).  Contributes to the induction of sneezing following exposure to chemical irritants or allergens which causes release of NMB by nasal sensory neurons and activation of NMBR-expressing neurons in the sneeze-evoking region of the brainstem (PubMed:34133943).  These in turn activate neurons of the caudal ventral respiratory group, giving rise to the sneezing response (PubMed:34133943).  Contributes to induction of acute itch, possibly through its activation on dorsal root ganglion neurons by the NMB peptide (PubMed:30734045).  Plays a role in the innate immune response to influenza A virus infection by enhancing interferon alpha expression and reducing expression of IL6 (PubMed:31601264).  Plays a role in CSF1-induced proliferation of osteoclast precursors by contributing to the positive regulation of the expression of the CSF1 receptor CSF1R (PubMed:28780306).
What are the official names of this protein?
Neuromedin-B receptor, NMB-R, Neuromedin-B-preferring bombesin receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MSTO1_MOUSE
Sequence: MAGGAREVLTLQLGHFAGFVGAHWWNQQDAALGRMAEDEESPGELCPDVLYRTGRTLHGQETYTPRLILMDLKGSLNTLKEEGNLYRDRQLEAAVAWQGKLSTHREDAHPKNPNLQGLLSAEGVRSSDGAWRAKLIQNIQNGKENSIKVWSDFLRVHLHPRSICVIHKYHHDGETGRLEAFGQGESVLKEPRYLEELEDRLHFYVEECDYLQGFQLLCDLHDGFSGVGAKTAELLQDEYAGRGVLTWGLLPGPYSLGEPQKNIYRLLNTAFGLVHLTGYSSFVCPLSLGGNLGLRPKPPVNFPSLHYDATLPFHCSAILATALDTVTVPYRLRSSMVTMAHLADVLSFSGKKVVTAEAIIPFPLVRGQSLPDILTQLGEATPWTSLSACGDSAGHRCFAQSVVLRGIDRASHTSKLNPGTPLPSALHACASGEEVLAQYLQQQHPRVLSSSHLLLTPCKVAPPYPHFFSSFSQKGLAMDSTPKGAAVQSIPVFGALRSTSSLHRTLGDLAEELSRLDLRRWASFMDAGVEQDDMEEMLHELHRLAQCYQEGDSLSN
What is the function of this protein?
Involved in the regulation of mitochondrial distribution and morphology.  Required for mitochondrial fusion and mitochondrial network formation.
What are the official names of this protein?
Protein misato homolog 1.
What is the protein family that this protein belongs to?
Belongs to the misato family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane. Cytoplasm.
Protein: RL16_CUPTR
Sequence: MLQPKRRKYRKEQKGRNTGKATRGNAVSFGEFGLKAMGRGRLTARQIESARRAMTRHIKRGGRIWIRIFPDKPISKKPAEVRMGNGKGNPEYYVAEIQPGKMLYEMDGVSEDLAREAFRLAAAKLPIATNFVVRQVGT
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.