PharMolix/UniProtQA huggingface dataset:
Protein: DAPF_MYCTA
Sequence: MIFAKGHGTQNDFVLLPDVDAELVLTAARVAALCDRRKGLGADGVLRVTTAGAAQAVGVLDSLPEGVRVTDWYMDYRNADGSAAQMCGNGVRVFAHYLRASGLEVRDEFVVGSLAGPRPVTCHHVEAAYADVSVDMGKANRLGAGEAVVGGRRFHGLAVDVGNPHLACVDSQLTVDGLAALDVGAPVSFDGAQFPDGVNVEVLTAPVDGAVWMRVHERGVGETRSCGTGTVAAAVAALAAVGSPTGTLTVHVPGGEVVVTVTDATSFLRGPSVLVARGDLADDWWNAMG
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_SALSV
Sequence: MSRVAKAPVVVPAGVDVKINGQVITIKGKNGELTRTLNDAVEVKHADNALTFGPRDGYADGWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGNVVNLSLGFSHPVDHQLPAGITAECPTQTEIVLKGADKQVIGQVAADLRAYRRPEPYKGKGVRYADEVVRTKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RS8_NOSP7
Sequence: MAANDTIADMLTRIRNANLARHQTTQVPATKMTRSIAKVLREEGFIAEIEEAEEGVKHNLVISLKYKGKNRQPLITALKRVSKPGLRVYSNRKELPRVLGGIGIAIISTSSGIMTDREARRQNLGGEVLCYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: COBS_LEPIN
Sequence: MNKLQEEWNRFCASWMFNTRLPILPFYVYSESTLSRSSRYFPLIGWIVSAGTSYSTYFLSWILPIEISIILGMILSVLITGGFHEDGLADVCDAFGGGWSKEKILEIMKDSRIGTFGSIGLILSLGLKYLLLVNLFKISPWIFLFTSWFSHSASRWFALLLMMLIPYARENDLSKSKPMIKKLPPFDFALSTFFGCFPAVYFLYQFQNQIPNVLLGFFLSSIFVFYFRNYFNKWIEGFTGDCLGFIQQGTELLFYLGITVSWNSI
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CAD11_HUMAN
Sequence: MKENYCLQAALVCLGMLCHSHAFAPERRGHLRPSFHGHHEKGKEGQVLQRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVIDDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQEAKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGALLSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQKKEPLIVFEEEDVRENIITYDDEGGGEEDTEAFDIATLQNPDGINGFIPRKDIKPEYQYMPRPGLRPAPNSVDVDDFINTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLDYDYLQNWGPRFKKLADLYGSKDTFDDDS
What is the function of this protein?
Cadherins are calcium-dependent cell adhesion proteins.  They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.  Required for proper focal adhesion assembly (PubMed:33811546).  Involved in the regulation of cell migration (PubMed:33811546).
What are the official names of this protein?
Cadherin-11, OSF-4, Osteoblast cadherin, OB-cadherin.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: USV1_YEAST
Sequence: MENTTNRNTAGVLTSSNGNFATNSVAASTPKRSKSARRKTFKCTGYDGCTMSFTRAEHLARHIRKHTGEKPFQCPACLKFFSRVDNLKQHRESVHAHKNHHSTSSHQRKPSSSSLSSSSSASSSSSASSSTSYSDPYRKTNINSGNMPMMAENEKAPQIIHSSPEFITSTRSIPPISPRSIYNTQRQQQHQQQQHQQAPYYFPSHPITDSYYQYPLPSNNNTINYLPSVDVQYPLNVSPSSTSHPASEVIISSFPPRSMPSTSFKYKDSADFQARTTMNKYNIRPSNINVNTSNINNHLDSFSPPFSPSTTVAEAKPIILPQYQQAFSQPPNGNKNNNMSSSKNGGKGGENFKNTDDRNDNNNKKRSETLSESDISVNTNKKRLSVDYILT
What is the function of this protein?
Transcription factor that participates in the transcriptional activation of glucose-repressed genes during exponential growth in non-fermentable carbon conditions.  Also involved in salt-stress response.
What are the official names of this protein?
Nutrient and stress factor 1, Up in starvation protein 1.
What are the subcellular locations of this protein?
Nucleus. Note=Found in the nucleus in conditions under which NSF1 is actively transcribed, such as growth with non-fermentable carbon sources or salt stress.
Protein: ILVD_LEPBJ
Sequence: MSDILKKRSSMTTDGDNRAPNRAMLRAVGFTDEDFHKPMIGIASTWSEVTPCNIHINKLAEKVKEGVRTAGGVPQIYGTITVSDGITMGHEGMHFSLPSREVIADSIEIVSNAMRHDGVIAIGGCDKNMPGCLMALCRIDAPSIFVYGGTILPGHCDGQDVDIVSIFEAVGKFNAGKISREEFIRIEQNACPGAGSCGGMYTANTMSSAIEALGMSLPGSASMPAVSSRKSEDCYEAGKALINLIQKGVTPKRILTKKAFENAITVVLVLGGSTNAVLHLIAIAKEIGVDLTLEDFDRISKKTPHLADLKPGGRYAMTDLDKVGGVHGVMKYLLKEGMLHGDCLTVTGKTIAENLMDMPDLVPNQTIVRKKSEALHPSGPLVILKGNLAPEGAVAKISGLKKISITGPAKVFESEDDCFNAIMTDQIKPGDVIIIRYEGPKGGPGMREMLAVTSALVGKGLGEDVGLMTDGRFSGGTHGLVVGHISPEAFDGGPIAIVQNGDAVTIDSGKNLLQVEISQEEIQKRLKNWKPIEPRYKSGVLAKYAKLVQSATNGAITNLL
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: LUXS_STAA1
Sequence: MTKMNVESFNLDHTKVVAPFIRLAGTMEGLNGDVIHKYDIRFKQPNKEHMDMPGLHSLEHLMAENIRNHSDKVVDLSPMGCQTGFYVSFINHDNYDDVLNIVEATLNDVLNATEVPACNEVQCGWAASHSLEGAKTIAQAFLDKRNEWHDVFGTGK
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: Y1313_THEMA
Sequence: MKNVRKIFTAIIEYDPEKKQYVGMVPDVPGVHTVGSSLEEVRRNLKEVLELVLEEAGDEINLQEFVALEMIEVET
What are the official names of this protein?
UPF0150 protein TM_1313.
What is the protein family that this protein belongs to?
Belongs to the UPF0150 family.
Protein: RL21_RALSO
Sequence: MYAVVKTGGKQYKVAAGEKLKVEQIPADVGAEITLDQVLAVGAGDQLKVGAPLVSGAAVKATVISHGRHDKVKIFKMRRRKHYQKHQGHRQNYTELRIDSIVA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: MATK_DRIGR
Sequence: MEELQGYLEIDGSRQQCFLYPLFFQEYIYALAHDHGLNGSILYKPMEIFGYDNKFSSLIGKRLITRMHQQNHLILSVKDSKQNLFVVPNKYFDSQMMSEVFAVIVEIPFSLRLVSSLEEKKIAKSHIRSIQSIHSIFLFFEDKFSHLNHVSDILIPHPIHLEILVQTLRCWIQDAPSLHLLRFFLYESRNSNSLIIPKKSISFFSKRNQRFFLFLYNSHIYGCESIFVFLRKQSSHLRSTSSRTLLERTHLYGKIEHFLVVLRNDFQRTLWLFKDPFMHYVRYQGKAIMASKGTHFLMKKWKYHLVNLWQCHFYLWSQPDSIHINQLYNHSFYFLGYLSRVQLNPSVVRSQMLENLFIIDTAINKFETIVPMIPLIRSLAKAKFCNVSGHPISKPARADSSDSDIIDRFGRICRNLFHYHSGSLKKQSLYRIKYILRLSCARTLARKHKSKVRAFLKRLGSGFFQEFLTEEEQVLSLIFPRTYSTSHRSHSERIWYLDIIRINDLANHE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS4_ACTP2
Sequence: MARYLGPKLKLSRREGTDLFLKSGVRAIESKCRNRLDVAPGQHGARKPRLSDYGSQLREKQKVRRIYGILERQFRNYYTEANRLKGNTGENLLVLLEGRLDNVVYRMGFAATRAEARQLVSHKSIVVNGRVVNIPSYQVSVDDVVAVREKSKKQARIKASLELATQREKPTWLEVDATKMEGVFKRTPERSDLSADINEHLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: ACCD_BACCQ
Sequence: MLRDLFVKKKKYAAIPSEQVRKDVPDGVMTKCPKCKKIMYTKELLKNLKVCVNCGYHHPMNAWERLDSILDEGSFREYDKEMVSLNPLEFPDYEEKLESDRKKTDLNEAVVTGEGTIDDMLVVVAVMDSRFRMGSMGSVVGEKIARAVEKAYDLQVPFIIFTASGGARMQEGILSLMQMAKTSVALKKHSNAGGLFISVMTHPTTGGVSASFASLGDYNLAEPGALIGFAGRRVIEQTVREKLPEDFQTAEFLLEHGQLDAVVHRDDMRESLRKILEVHQGGEMAVWQS
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABZ_POLNS
Sequence: MSTPIAIDINKILKLLPHRYPFLLVDRVLEISPRESITALKNVTMNEPFFQGHFPGFPMMPGVLIIEALAQTAALLTFSDERAEDAIYYFAGIDGARFKKPVLPGDQLIMTAKLERDRAGIYKFAVQATADGEIAAEANITCAVRTKGA
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAX_DESAL
Sequence: MLLVIDVGNTNTVMGVFDDQRVVCDWRIRTERETTEDEFFVLASQLFAGKDIKPEIITATIVSCVVPPMRKILHAFCKKYLGHEPIWVSAEMDMGMPILYDNPAEVGADRIVNAVAAYERYHDALIVIDFGTATTFDCISKDGEYLGGAISPGVGIASEALFARASKLPRVEIFNPPAQAIGKDTAKSMQSGIILGYAGLVDGLVRRIVKEMENKPRVIATGGLAPLMANVAETIEEVESGLTLEGLRIIFDRVSNS
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_STRPC
Sequence: MSRKNQAPKREVLPDPLYNSKIVTRLINRVMLDGKRGTAATIVYDAFSAIKEATGNDALEVFETAMDNIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLRWLVNASRARGEHTMKDRLAKEIMDAANNTGASVKKREDTHKMAEANRAFAHFRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RL23_STRZT
Sequence: MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEAAFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: EFG_SYNSC
Sequence: MARDFPLERVRNIGIAAHIDAGKTTTTERILFYSGVVHKIGEVHDGAAVTDWMAQERERGITITAAAISTSWQDHRINIIDTPGHVDFTIEVERSMRVLDGVIAVFCAVGGVQPQSETVWRQADRYSVPRMVFVNKMDRTGADFLKVHGQIKDRLKANAVPIQLPIGAEGELSGIIDLVANKAYIYKNDLGTDIEEADVPADMADEVAEWRNTLMETVAETDEALIEKFLESGELSVDDLKKGIREGVLKHGLVPMLCGSAFKNKGVQLVLDAVIDYLPAPVDVPPIQGVLPDGSEAVRPSDDSAPFSALAFKVMADPYGKLTFVRMYSGILEKGSYVLNSTKGEKERISRLVVLKADDREEVDALRAGDLGAVLGLKNTTTGDTLCTQDDPIVLETLFIPEPVISVAVEPKTKGDMEKLSKALVALAEEDPTFRVNTDSETGQTVIAGMGELHLEILVDRMLREFKVEANIGAPQVSYRETIRGSAGGEGKFSRQTGGKGQYGHVVIEMEPGEPGSGFEFVNKIVGGVVPKEYIKPAEQGMKETCESGVIAGYPLIDVKCTLVHGSYHDVDSSEMAFKIAGSMAFKDGVKKCNPVLLEPMMKVEVEAPEDFLGSIIGDLSSRRGQVEGQSVEDGTSKISAKVPLAEMFGYATELRSMTQGRGIFSMEFDNYAEVPRNVAEAIISKNQGNS
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYR_SACD2
Sequence: MNIRNLLNDRVKSAMNDAGIPADYSPHLAVSKKAGFGDYQANGAMGAAKALKTNPREVAQKIIDNLDLNGIASKVEIAGPGFINIHLDPKWLAQQTVAVTNSTNLGILPKNNPETVVIDYSSPNLAKEMHVGHLRSTIIGDAIARVLEFTGDKVIRQNHVGDWGTQFGMLIAELEDQLGSGERPELALQDLEGFYQQAKKHFDDDPAFADRARDYVVKLQSGDAQVNKLWQEFRRVSLLHAEEIYRKLNVTLGEADVRGESAYNDDLAPVVAELEAQGLAVEDQGAKVVFLHELADKNGDPSVAIIQKKDGGYLYSTSDLAALRYRVGTLKANRILYFIDARQSLHMQQVFTLARKAGFADEWLSTEHHAFGTMLGSDGKPFKTRSGGTVKLAQLLDEAVERAAKEVRTKNPDLTEEEMAEVASKVGIGAVKYADLCKTRTNDYVFNWESMLAFEGNTGPYMQYAYTRIRSIFRRANENMDTFESEVNLTEPQEVQLAIKLLQLPEIVEQIAADAYPHVMCNYLYDLASLFMTFYEACPILKEGVEPAVKTSRLQLSKGVARTLAQGLDLLGIEVMEKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PQQB_PSEA8
Sequence: MHIRILGSAAGGGFPQWNCNCRNCRGVRDGSVAAQPRTQSSIALSDEGERWILCNASPDIRAQIAAFPALQPARRPRDTAIGAIVLLDSQIDHTTGLLSLREGCPHEVWCTQMVHQDLSEGFPLFPMLSHWNGGLRHRPIALDGEPFAIPACPRLRFTAIPLRSSAPPYSPHRGDPHPGDNIGLFVEDLDSAGTLFYAPGLGEVDEALLEWMRRADCLLVDGTLWRDDEMLVCEVGDKLGRQMGHLAQSGPGGMLEVLAKVPAARKVLIHINNTNPILDTASAERAELDASGIEVAWDGMHIQL
What is the function of this protein?
May be involved in the transport of PQQ or its precursor to the periplasm.
What are the official names of this protein?
Coenzyme PQQ synthesis protein B, Pyrroloquinoline quinone biosynthesis protein B.
What is the protein family that this protein belongs to?
Belongs to the PqqB family.
Protein: KHSE_HAEIN
Sequence: MLRIYAPASSANISVGFDTLGAAISPIDGSLLGDVVQIESISTGFELESAGYFVRKLPKEPQKNIVYQAYVLFSEQLKLRGANVKPLRLTLEKNMPIGSGLGSSACSIVAALVALNQFHNEPFSKMELLEMMGELEGRISGSIHYDNVAPCYLGGVQFMVQSLGNICQKLPFFDNWYWVLAYPGIEVSTAEARAILPKSYTRQNVIAHGRHLGGFVHACHTHQENLAAIMMKDVIAEPYRESLLPNFAEVKQATRDLGALATGISGSGPTIFSIAPDLQTAIKLSSYLESHYLQNNEGFVHVCKVDNEGTREIK
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y5378_BACCR
Sequence: MPYVTVKMLEGRTEEQKKALAEKVTAAVSETTGAPEENIVVFIEEMSKNHYAVGGKRLSDK
What are the official names of this protein?
Probable tautomerase BC_5378.
What is the protein family that this protein belongs to?
Belongs to the 4-oxalocrotonate tautomerase family.
Protein: TYSY_SHEB9
Sequence: MKQYLDLMKHILAEGVDKSDRTGTGTRSVFGYQMRFDLSKGFPLVSTKKCHMRSIIHELLWFLKGETNVAYLRENKVSIWDEWADDNGDLGPVYGAQWRSWPTQSGDAIDQISQVIAQIKSQPDSRRLIVSAWNVGELDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLTMMVAQQCDLALGDFVWTGGDTHLYSNHMEQTALQLSREPMPLPTMTILRRPESIFDYQFDDFELTNYAPHPHIKAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ODR7_CAEEL
Sequence: MIVPDTEGLLIYSYGLMYGSYCMACQMLIPHFQCIPGIFPNFRISTELIKTMTDKLEQPNNNVPQQPWGPFPPAFGGRPSGEQTDGNPGEFDNDAAHQQTAPFMTHFFPRIGLQFPDFTEYQRFNGFQRNAFFPNPFGSQFTGQAFAQSFPLHNSMTTMDGFNLTHAPHPFSTNTNSTKPKDIENTVQSTIKHSSENIQDKPPVLSVEYPVKYDSELKFDANVDFTAVPKQESSDDSTLKNLKKSDQQLQQPQQFTFPPPLLAEKSFEQPRMREDVLPFHPQFYPAPLDMGTNFKQEMRTPPIDGHIDYRKFDASGKRMEFQPPGALHDCQVCLSTHANGLHFGARTCAACAAFFRRTISDDKRYVCKRNQRCNNASRDGTGYRKICRSCRMKRCLEIGMLPENVQHKRNRRDSGSPPRKTPFDTFFNGFYPSFQPSGSAAQPITVSSSESPRHTTN
What is the function of this protein?
Required for the function of one pair of chemosensory neurons called AWA neurons that are involved in chemotaxis to volatile odorants.  Acts in a pathway that specifies olfactory neuronal fate.  Regulates the transcription of olfactory signaling molecules such as odr-10 that specify AWA neuron identity and function.  Represses the expression in AWA neurons of factors such as str-2 which specify AWC neuron identity.
What are the official names of this protein?
Nuclear hormone receptor family member odr-7, Odorant response abnormal protein 7.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR0 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, perinuclear region.
Protein: OMP2A_BRUSU
Sequence: MNIKSLLLGSAAALVAASGAQAADAIVAPEPEAVEYVRVCDAYGAGYFYIPGTETCLRVHGYVRYDVKGGDDVYTGSDRKGWDKGARFALMFNTNSETELGTLGTYTQLRFNYTSNNSRHDGQYGDFSDDRDVADGGVSTGTDLQFAYITLGGFKVGIDESEFHTFTGYLGDVINDDVVAAGSYRTGKIAYTFTGGNGFSAVIALEQGGEDVDNDYTIDGYMPHVVGGLKYAGGWGSIAGAVAYDPVIEEWATKVRGDVNITDRFSVWLQGAYSSAATPNQNYGQWGGDWAVWGGAKFIATEKVTFNLQAAHDDWGKTAVTANVAYQLVPGFTITPEVSYTKFGGEWKDTVAEDNAWGGIVRFQRSF
What is the function of this protein?
Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane.
What are the official names of this protein?
Porin Omp2a.
What is the protein family that this protein belongs to?
Belongs to the alphaproteobacteria porin family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: SYI_METI4
Sequence: MDYSLTVLLPKTDFPMKANLPQREPHWIEVWEKEKVYSTLLEKRKNCPQFILHDGPPFANGKAHMGSGLNKILKDIVLKSRNMLGFQCPYIPGWDCHGLPIEHKVMSEYPALAADPLSIRNKCKEYARYWIEIQKEQFRRLGILGSWDNPYITMDPGYEAAELRLFAELVEKKWVYRGLRPVFWSVGCRTALAEAEIEYQKKEDIAIYVEFPVGEEELKKAGLPQGTSFLAWTTTPWTLPANLALAVSPDLSYELRQVGGKKFIVAGKLAESIPGFSHSVVLLSFPSGQNLEGLKYNHPLLPREGVVYTADFVSGETGSGIVHIAPGHGMEDYQLGMVHGLEVYSPVDDQGRFTKQCGIEKIVGLSVFEANSILCAMLKEKGLLWAKYPYVHDYPFCWRSKTPIIFRSVPQWFIAIEAFKSLALKEIERVNWIPSRGENRIKGAVESRKDWCISRQRYWGVPIPAFYKKSGEAILDPSIIRRFADKVEEEGTDLWFRLESKELCQLLGLAPSEDLVKGLDTLDVWIDSGSSHYSVLKPRGEDPADLYLEGSDQHRGWFQSSLLLSVASKGKAPYKSVLTHGFVVDLDGKKLSKSSGARDLSEQIQTYGADLLRLWVASEEYAEDVPFSKEIFSRLSDSYRLIRNSLRILLGNLHDFNPQEQSLPDDRLREIDRYFELCVNKLVKKTKAFYENYEFSQVYQALTRFCSVELSSFYIDILKDRLYCDGQNWLSRRSAQTVLYRTFECLVKLLAPILPFTTEEAWRASGKTSSIHLELFPEEREIKEEEKLLKRWEKILQLRDLANRELEKARKQKMIGKNLEAKLILFTDDFEAEDTALLTEVFLVSQLEIIRSSKTEILVEKALGKKCPRCWKFSLFAQSNSDPQYPHVCPRCLKVLKGLPESFLVSD
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCUP_LEGPH
Sequence: MFDLNQSLFLRALRRQPVERTPIWIMRQAGRYLPEYRKVREHAGDFLNLCKNPELACEVTLQPLRRYALDAAILFSDILTIPDAMGLGLYFAEGEGPRFTNPLQDTKAIHTLKIPSIPESLSYVFDAARLIRQEMPKELPLIGFSGSPWTLACYMVEGGSSRDFKRILNLIYTEKEAAHLLLNKLAVSVTAYLIEQIKAGVNAVMIFDTWGGVLTPQNYKDFSLAYMHQIVQQLKKEYPDIPVILFTKNGGQWLEWMAETGCDALGVDWTCDLASARKRVGGKVALQGNLDPAVLLTTKNCIRSEVGSVLASYGYGTGHIFNLGHGITPDVPPENVAIMIEAVHEISPQYHL
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABZ_SHESH
Sequence: MSNQLNTMDIKEIMNSLPHRYPFLLIDRVLDYTPGETLHAIKNVTINEPFFQGHFPIQPVMPGVLILEAMAQATGLLAYKTMEAAVTDDSLYYFAGIDKARFKRVVEPGDQLHFEVKMVKERRGIGVFTGVVKVDGELVCSAEIMCARREIKK
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.