PharMolix/UniProtQA huggingface dataset:
Protein: SYA_PSEMY
Sequence: MKSAEIREAFLSFFEEKGHTRVASSSLIPANDPTLLFTNAGMNQFKDCFLGLEKRAYTRATTSQKCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKRDAIHYAWEFLTSDKWLNLPKEKLWVTVYATDDEAYEIWNKEIGVPAERMIRIGDNKGAPYASDNFWAMGDTGPCGPCTEIFFDHGEHIWGGPPGSPEEDGDRYIEIWNNVFMQFNRTADGVLHPLPAPSVDTGMGLERISAVLQHVNSNYEIDLFQNLLAASAKAIGCANEGQASLKVVADHIRSCSFLIADGVTPSNEGRGYVLRRIVRRACRHGNKLGAKGSFFYQIVAALVAEMGEAFPELKQQQAHIERVLKTEEEQFAKTLEQGLKILEQDLAGLQGSVIPGDIVFKLYDTYGFPVDLTADIARERELSVDEEGFEREMEAQRERARSASAFGMDYNALVKVDADTRFLGYEGTSGSGKIIALFKAGAAVDSLAEGEEGVVVLDQTPFYAESGGQIGDCGYLESAGMRFDVRDTTKAGGAFLHHGVVAKGGLSVGTSVKAEAEASVRQATALNHSATHLLHAALRQVLGDHVQQKGSLVDSQRLRFDFSHFEAIKPEQLKQLEDIVNAEIRKNSEVETEETDIETAKAKGAMALFGEKYGDQVRVLSMGGDFSVELCGGTHVSRTGDIGLFKITSEGGVAAGVRRIEAVTGAAALAWLNAAEEQLKEAASLVKGSRDNVLDKLSALIERNRQLEKELEQLKAKAASAAGNDLAGSAVDLKGTKVLAARLDGLDGKALLALVDQLKNKLGSGVILLGGVFDEKVVLVAGVTQDLTAKLKAGDLMRQAAAAVGGKGGGRPDMAQGGGVDAGKLDEALALAATFVEQGL
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPA_EHRRG
Sequence: MKSKPDWLKVKMPTGSAFYEMRNLMKLHKLNTVCEEAACPNIGECWNKKHATVMILGSTCTRACAFCNVASGIPDKLDPHEPQSLAKAVSSLKLQHVVITSVDRDDLEDGGAGHFVECIEEIRKRDSNVTIEILTPDFLNKHDAIDKIAKAFPDVYNHNVETVPRLYAKIRPKARYFHSLYLLKTIKQKNPRIFTKSGIMVGLGELKEEIYQVMDDLRSADVDFIVIGQYLQPTSKHAVVDRYVTPEEFDHYKYVAYSKGFLMVASGPLVRSSYHAEEDFQRLKKNRAAMYT
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GID2_ORYSJ
Sequence: MKFRSDSSGGDEPRAPAAGDGGGGGDEPAKRQRTDPSSSSSQGEASSSSQPPPQQQQEEQPPEDAGEGEQPRVPDLGEDLVFEVLRRAEARTLAAAACVSRGWRQLAEDERLWEAACVREWANLGFSERQLRAVVLSLGGFRRLHAVYIRPLQWRGAGVPRQQGRRQPPVRLGRDQVQLSLSLFSIGFFQNMPCPKKDKGNDSDKNGGGQCG
What is the function of this protein?
Essential component of some SCF-type E3 ligase complex that positively regulates the gibberellin signaling pathway.  Upon gibberellin treatment, the complex mediates the ubiquitination and subsequent degradation of DELLA protein SLR1, a repressor of the gibberellin pathway, leading to activate the pathway.
What are the official names of this protein?
F-box protein GID2, Gibberellin-insensitive dwarf protein 2, Protein GIBBERELLIN INSENSITIVE DWARF2.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS4_CAMHC
Sequence: MEILPAIDLKNGFAVRLKKGEMNSAKIYSDKPWELAEKFADLGAKWLHIVDLDGAFAGEAKNAKTIEKIVKSTNLKIEVGGGIRDEERIKFYKNSGVSRFILGSAALKNPEFVKQMAKKYKIAVGIDAKNGFVATEGWAEVSNIKACELAKIYADAGVEAIICTDISKDGMLSGVNVKFSEEIAKSSGIKTIASGGVKDLSDIKALKQSGKIYGVIVGKAYYEGSIDLKEAFLIAK
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHG36_AILME
Sequence: MGGCNPFLKAARTLCPRIMPPLLFLSAFIFLVNVLGGAPGHNPDRRTKMISIHSLSELERLKLQETAYHELVARHFLSEFKPDRALPIDRPNTFEKWFLILRGQQRAVSLKTFGIRLEEVLVNELTRRKHLELTAAMQIEESTGQASGRRRGNVVQRLFGRIRRFFSSRRDEPSLPREFTRRGRRGAVSVDSLAELEDGALLLQTLQLSKISFPIGQRLLGSKRKMSLNPIAKQIPQVVEACCSFIEKHGLSAVGIFTLEYSEERVRELREEFDQGLDVVLDDTQNVHDVAALLKEFFRDMKDSLLPDDLYMSFLLTATLKPQDQLSALQLLVYLMPPCHSDTLERLLKALHKITENCEDSIGIDGQLVSGNRMTSTNLALVFGSALLKKGRFAKRESRKTRLGIDHYVASVNVVRAMIDNWDILFQVPPHIQKQVAKRVWKSSPEALDFIRRRNLRKIQSARIKMEEDALLSDPVENSAEAWAAVLAQSKPFDEGSSEEPAVPPGTAHSHDDEEGAGNPPIPEQDRPLLRVPREKQAKTGIGYFFP
What is the function of this protein?
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
What are the official names of this protein?
Rho GTPase-activating protein 36.
Protein: RLME_AGRRK
Sequence: MTKPTIAGNRTGRKLGQRVKKKKLKASSREWLHRHINDPYVQRAQLEGYRARAAFKLLEIDEKHQILKGARRIIDLGAAPGSWSQIAAKVTGSTEDDIRVAAIDFLEMAHLPGVTILQLDFLDPDAPQRLVDAVGGEPDLVMSDMAAPTTGHHRTDHLRTMHLCEVAAHFAIEVLAEGGHFLAKTFQGGTERDLLNLLKQNFRQVVHVKPGASRAESVEMFLLAKGFKGRNVEHGTISA
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_THESQ
Sequence: MPKVKTNRSAAKRFRITKNGKIMRNHAYRSHKTGKKRRNALRALRKKDVVSSADKNRVLRLLGKK
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: FABP3_FASHE
Sequence: MANFVGSWKLEQSENMDAVLQKLGINVIKRKLITSSKPEITFTLEGNKMTMKTVSALKTTVISFTFGEEFKEETADGRTVMTTFTKDSDSKISQVQKCPENTTHVVREVTGGKMIATVTVGDVKAVNNYHKV
What are the official names of this protein?
Fatty acid-binding protein type 3.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Protein: NU1M_ONCMY
Sequence: MITLITHVINPLAYIVPVLLAVAFLTLLERKVLGYMQLRKGPNIVGPYGLLQPIADGLKLFIKETVRPSTSSPFLFLATPMLALTLALTLWAPMPIPYPVTDLNLGVLFVLALSSLAVYSILGSGWASNSKYALIGELRAVAQTISYEVSLGLILLSVIIITGGFTLQTFNVAQESIWLLVPAWPLAAMWYISTLAETNRAPFDLTEGESELVSGFNVEYAGGPFALFFLAEYANILLMNTLSAVLFLGASHIPAFPELTALNLMTKAALLSVVFLWVRASYPRFRYDQLMHLVWKSFLPLTLALVLWHLALPIALAGLPPQL
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RT25_BOVIN
Sequence: MPMKGRFPIRRTLQYLSQGDVVFKDSVKVMTVNYNTHGELGEGARKFVFFNIPQIQYKNPWVQIMLFKNMTPTPFLRFYLDSGEQVLVDVETKSNKEIMEHVKKILGKNEETLRRERQEREQLSHPAHFGPRKYCLRECICEVEGQVPCPAVVPLPRELTGKFQAALRAGAQD
What are the official names of this protein?
28S ribosomal protein S25, mitochondrial, MRP-S25, S25mt.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mS25 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PXPA_TOLAT
Sequence: MAQVDLNCDMGESFGIYQMGTDTQIMPLVSSANIACGFHAGDPSVMRKTLEAAVAQGVALGAHPGLPDLVGFGRRNMQVSAQEAYDMVVYQVGALAGFAKAAGVSLHHVKPHGALYNMAAKDKALADAIARAVRDIDASLVLYGLAGSQLIQAGKNAGLRVASEVFADRTYQADGSLTSRSQPNALLQSDEEAVQQVLTMVTEKRVKAVTGEWVSLDADTICIHGDGAHALSFATKVRAALLQAGVEIKAM
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: OPP11_HAEIN
Sequence: MKKFNQSLLATAMLLAAGGANAAAFQLAEVSTSGLGRAYAGEAAIADNASVVATNPALMSLFKTAQFSTGGVYVDSRINMNGDVTSHATIITSSSGIKAIEGGSASARNVVPGAFVPNLYFVAPVNDKFALGAGMNVNFGLKSEYDDSYDAGIFGGKTDLSAINLNLSGAYRVTEGLSLGLGVNAVYAKAQVERNAGIIADSVKDNQVKTALTVQQEPLKFLDKYLPSKDTSVVSLQDRAAWGFGWNAGVMYQFNEANRIGLAYHSKVDIDFTDRTATSVEANVIKAGKKGDLTLTLPDYLELSGFHQLTDKLAVHYSYKYTHWSRLTKLNASFEDGKKAFDKELQYSNNSRVALGASYNLDEKLTLRAGIAYDQAASRHQRSAAIPDTDRTWYSLGATYKFTPNLSVDLGYAYLKGKKVHFKEVKTIGDERSLTLNTTANYTSQAHANLYGLNLNYSF
What are the official names of this protein?
Outer membrane protein P1, OMP P1.
What is the protein family that this protein belongs to?
Belongs to the OmpP1/FadL family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: ACBD6_DANRE
Sequence: MASRSPSSSPDSATGSGTDPARPDTGEPLGGGSDSDSDFGLGKFDCSAGDASARLEGADLENEFESAADRVRDLVQTASREQLLYLYARFKQVKVGKCNTSKPGFFDFEGQRKWSAWKQLGDMSAEQAMQEYVTCVHALDPEGSQKSSERRGGEKRTGFGGPAVSSLYQEEKIREEDKNIFDYCRENNIEHVSKAISSKTVDVNTRDEEGRALLHWACDRGHKDLVSLLLQNNADINSQDDEGQTALHYASACEFAEIVELLLKAGADPSIKDQEGSLPEEVTESSAISSLLRQYTAPKG
What is the function of this protein?
Binds long-chain acyl-coenzyme A molecules with a strong preference for unsaturated C18:1-CoA.  Does not bind fatty acids (By similarity).
What are the official names of this protein?
Acyl-CoA-binding domain-containing protein 6.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBS1_CHLRE
Sequence: MAAVIAKSSVSAAVARPARSSVRPMAALKPAVKAAPVAAPAQANQMMVWTPVNNKMFETFSYLPPLTDEQIAAQVDYIVANGWIPCLEFAEADKAYVSNESAIRFGSVSCLYYDNRYWTMWKLPMFGCRDPMQVLREIVACTKAFPDAYVRLVAFDNQKQVQIMGFLVQRPKTARDFQPANKRSV
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, chloroplastic 1, RuBisCO small subunit 1.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HUTI_PHOLL
Sequence: MVIELRDTDIIWRNARLATMDPAVNAAYGLLKEYDLVVRDDKILAILPTAALQTSRCQVIDVQQRLITPGLIDCHTHLVFGGNRAYEWEQRLNGMSYAELSAQGGGINATVSATRASSHEQLERSAQQRLTAFMAEGVTTIEIKSGYGLNLENEEKLLQVVQHLAQHNPIEISPTLLAAHTCPPEYKHNPDAYMDLICEDILPQLWQKGLFEAVDVFCESVGFNLAQTERLFQAAQRWNIPVKGHVEQLSHLGGSELVARYHGLSVDHIEYLDQAGVESLSHSGTVAVLLPGAFYFLQETRCPPIDLLRQFNVPIAVSTDFNPGTSPFASLRMAMNMACVQFGLTPEEVWLGVTRHAARALGREPRHGQLRAGAYADFVVWDAENPVDIFYELGHNPLNTRVFRGVMTHSSIYNR
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISDA_STAA8
Sequence: MTKHYLNSKYQSEQRSSAMKKITMGTASIILGSLVYIGADSQQVNAATEATNATNNQSTQVSQATSQPINFQVQKDGSSEKSHMDDYMQHPGKVIKQNNKYYFQTVLNNASFWKEYKFYNANNQELATTVVNDNKKADTRTINVAVEPGYKSLTTKVHIVVPQINYNHRYTTHLEFEKAIPTLADAAKPNNVKPVQPKPAQPKTPTEQTKPVQPKVEKVKPTVTTTSKVEDNHSTKVVSTDTTKDQTKTQTAHTVKTAQTAQEQNKVQTPVKDVATAKSESNNQAVSDNKSQQTNKVTKHNETPKQASKAKELPKTGLTSVDNFISTVAFATLALLGSLSLLLFKRKESK
What is the function of this protein?
Cell wall-anchored surface receptor that participates in the extraction of heme from oxidized methemoglobin/metHb to enable growth on hemoglobin as a sole iron source (By similarity).  Receives heme from IsdB and transfers it to IsdC (By similarity).  Also plays a role in the inhibition of host immune response.  Protects S. aureus against the bactericidal protease activity of apolactoferrin.  Decreases bacterial cellular hydrophobicity, which renders S. aureus resistant to bactericidal human skin fatty acids as well as to beta-defensins and cathelicidin.  Also binds fibronectin and chains B-beta and gamma of fibrinogen, promoting clumping of S. aureus with fibrinogen.  Involved in adherence of S. aureus to human desquamated nasal epithelial cells and is required for nasal colonization (By similarity).
What are the official names of this protein?
Iron-regulated surface determinant protein A, Fur-regulated protein A, Staphylococcal transferrin-binding protein A.
What is the protein family that this protein belongs to?
Belongs to the IsdA family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor. Note=Encodes an LPXTG motif-containing sorting signal that targets to the cell wall, which is catalyzed by sortase A.
Protein: RL23_STAAR
Sequence: MEARDILKRPVITEKSSEAMAEDKYTFDVDTRVNKTQVKMAVEEIFNVKVASVNIMNYKPKKKRMGRYQGYTNKRRKAIVTLKEGSIDLFN
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: RL2_PHOLL
Sequence: MAIVKCKPTSPGRRHVVKVVNPELHKGKPYAPLLEKSSKTGGRNNNGRITTRHIGGGHKQHYRLIDFKRNKDGIPAVVERLEYDPNRSANIALVLYKDGERRYILAPKGLKAGDQIQSGVDASIKTGNALPMRNIPVGSTVHNVEMKPGKGGQLARSAGAYVQIVARDGSYVTLRLRSGEMRKVLSDCRATLGEVGNAEHMLRVLGKAGASRWRGIRPTVRGTAMNPVDHPHGGGEGRNFGKHPVTPWGVQTKGKKTRSNKRTDQFIVRRRTKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: SC5AC_DANRE
Sequence: METVGRFQAGDYVVFACLFVVSSGIGVFFAIKERNKAPSKEFLVGGRQMSCGPVALSLTASFMSAVTVIGAPADVYRFGASYVIFGVAYTFVVFFTAELFLPVFYRSGITSTYEYLELRFCKLVRVAATLIYIIQTILYTGVVVYAPALALNQVTGFDLWGSIFATGIVCTFYCTLGGLKAVVWTDAFQMVVMVVGFLTVLIQGSSRAGGIENVWSTSRTGGRLQVFDFDVSPLRRHTFWTLSVGGTFTWLGIYGVNQSTIQRCISCKTEGHARWALYLNLLGLWIILFCAVVSGLIMYSYYSHCDPWSSGLISAPDQLMPYFVMEILGAFPGLPGLFVACAFSGTLSTVAASINALATVMYEDFVSQCFPDLSNRAASWISKALCVAFGVACTTMAVAASYMGGIVQAALSIHGMCGGPVLGLFSLGILFPFTNLKGAVGGLIVGISLSFWVGVGAFIYPAPSNNTHALELNTAGCNITAAAFEPTSATVTQLTSDRNWLADSWYSMSYLYYSAVGFIGTVAAGLLITLLTGPMDPKLLKPGMTRSVKEVMCFCTEKFTEADLGEGKEDVGDFGKAWEKHPDQGCTLRMDEKFRCSCDNQQENGNTNAGFDHNETSIVQKKL
What is the function of this protein?
Acts as an electroneutral and low-affinity sodium (Na(+))-dependent sodium-coupled solute transporter.  Catalyzes the transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, nicotinate, propionate, butyrate and beta-D-hydroxybutyrate.
What are the official names of this protein?
Sodium-coupled monocarboxylate transporter 2, Electroneutral sodium monocarboxylate cotransporter, zSMCTn, Low-affinity sodium-lactate cotransporter, Solute carrier family 5 member 12, zSLC5A12.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GLMM_DESRM
Sequence: MAKLFGTDGVRGVANTELTAELAFRLGRAGAHVLTRQGHSKKIIIGRDTRISGDMLEAALVAGICSVGVDVYKIGVLPTPGIAYLTRKLGAGAGVVISASHNPVQDNGIKFFGPSGYKLPDELESQIEKLALDDQAELPRPTGGELGRLYYVEDAVDQYVDFAKATISTDLKGLKIVVDCANGAAYAVAPRILSELGAEVIPIFHRPDGVNINAHCGSTHPETLMEEVVKQGADLGLAHDGDADRVLAVDHLGNLVDGDQIMVLCAKHLKSKGKLRKNTTVVTVMSNLGLYKALERSGIEVVETKVGDRYVLEKLLETGARFGGEQSGHIIFLQHNTTGDGIITALQLLAVVKETGMSLAQLAGQMERYPQILKNVQVKDKNYVMNSPIISEAIRRFERDLAGQGRILVRPSGTEPLVRIMVEGKDMAELQSIVDKMAEIVGNI
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: RTL1_ARATH
Sequence: MEDQETKRITKKPSRSIIISLKDIPPLDPSSIPSMKPMAQDHHNVGMQRFQEKTDFKFEEEDNAISSFSNIQIDPNSTRSISLEKKLAPKPDEEHTTTTKPISKDDESKTRRGSAKSVLHEMCASKRWRPPVYECCNVDGPCHLRLFTYKVMVEIRDSSGKTVLECFGDPRRKKKAAAEHAAEGALWYLEHVKTKPHQ
What are the official names of this protein?
Ribonuclease 3-like protein 1, Ribonuclease III-like protein 1, RNase III-like protein 1, Ribonuclease three-like protein 1.
Protein: WDR18_HUMAN
Sequence: MAAPMEVAVCTDSAAPMWSCIVWELHSGANLLTYRGGQAGPRGLALLNGEYLLAAQLGKNYISAWELQRKDQLQQKIMCPGPVTCLTASPNGLYVLAGVAESIHLWEVSTGNLLVILSRHYQDVSCLQFTGDSSHFISGGKDCLVLVWSLCSVLQADPSRIPAPRHVWSHHALPITDLHCGFGGPLARVATSSLDQTVKLWEVSSGELLLSVLFDVSIMAVTMDLAEHHMFCGGSEGSIFQVDLFTWPGQRERSFHPEQDAGKVFKGHRNQVTCLSVSTDGSVLLSGSHDETVRLWDVQSKQCIRTVALKGPVTNAAILLAPVSMLSSDFRPSLPLPHFNKHLLGAEHGDEPRHGGLTLRLGLHQQGSEPSYLDRTEQLQAVLCSTMEKSVLGGQDQLRVRVTELEDEVRNLRKINRDLFDFSTRFITRPAK
What is the function of this protein?
Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes (PubMed:22872859).  Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit (PubMed:21326211).  May play a role during development (By similarity).
What are the official names of this protein?
WD repeat-containing protein 18.
What is the protein family that this protein belongs to?
Belongs to the WD repeat IPI3/WDR18 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Cytoplasm. Dynein axonemal particle. Note=Mainly found in the nucleoplasm, with low levels detected in the cytoplasmic and chromatin fractions.
Protein: COX3_DROME
Sequence: MSTHSNHPFHLVDYSPWPLTGAIGAMTTVSGMVKWFHQYDISLFVLGNIITILTVYQWWRDVSREGTYQGLHTYAVTIGLRWGMILFILSEVLFFVSFFWAFFHSSLSPAIELGASWPPMGIISFNPFQIPLLNTAILLASGVTVTWAHHSLMENNHSQTTQGLFFTVLLGIYFTILQAYEYIEAPFTIADSIYGSTFFMATGFHGIHVLIGTTFLLVCLLRHLNNHFSKNHHFGFEAAAWYWHFVDVVWLFLYITIYWWGG
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: EFG2_VIBPA
Sequence: MTDLSKYRNIGIFAHVDAGKTTSTERILKLTGKIHKIGDTHDGSTTTDFMEQEAERGITIQSAATTCFWNDHRLNIIDTPGHVDFTIEVYRSLKVLDGGIGVFCGSGGVEPQSETNWRYADESHVSRLIFVNKLDRMGADFYKVVDQVQNVLGATPLVMTLPIGIEEDFVGVVDVLSQQAYVWDESGQPENYEVQEIPADMVDKAAEYREMLIETALEQDEDLMMAYLEEGEEPSVEDIKRCIRKGTRDLAFFPTYCGSAYKNKGMQLILDAVVDYLPSPTEVDPQPLTDPDTGEATGEVATVSADEPLKALAFKIMDDRFGALTFIRIYSGKMKKGDTVLNSATGKTERIGRMVEMHADERNEIDSAQAGDIIAVVGMKNVQTGHTLCDPKHECTLEPMIFPEPVISIAVKPKDKGGSEKMGIAIGKMVAEDPSFQVETDEESGETILKGMGELHLDIKVDILKRTYGVELEVGAPQVAYRETITQAIEDSYTHKKQSGGSGQFAKIDYRIKPGEVGSGFTFKSTVVGGNVPKEFWPAVEKGFAGMMETGVLAGFPTLDVEVELYDGGFHAVDSSAIAYEIAAKGAFRQSMPKAGAQLLEPIMKVDVFTPEDHVGDVIGDLNRRRGMIKDQQAGTTGVRIKGDVPLSEMFGYIGTLRTMTSGRGQFSMEFSHYSPCPNNVAEQVIADVKERNAKK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G 2, EF-G 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ELAS_PSEAE
Sequence: MKKVSTLDLLFVAIMGVSPAAFAADLIDVSKLPSKAAQGAPGPVTLQAAVGAGGADELKAIRSTTLPNGKQVTRYEQFHNGVRVVGEAITEVKGPGKSVAAQRSGHFVANIAADLPGSTTAAVSAEQVLAQAKSLKAQGRKTENDKVELVIRLGENNIAQLVYNVSYLIPGEGLSRPHFVIDAKTGEVLDQWEGLAHAEAGGPGGNQKIGKYTYGSDYGPLIVNDRCEMDDGNVITVDMNSSTDDSKTTPFRFACPTNTYKQVNGAYSPLNDAHFFGGVVFKLYRDWFGTSPLTHKLYMKVHYGRSVENAYWDGTAMLFGDGATMFYPLVSLDVAAHEVSHGFTEQNSGLIYRGQSGGMNEAFSDMAGEAAEFYMRGKNDFLIGYDIKKGSGALRYMDQPSRDGRSIDNASQYYNGIDVHHSSGVYNRAFYLLANSPGWDTRKAFEVFVDANRYYWTATSNYNSGACGVIRSAQNRNYSAADVTRAFSTVGVTCPSAL
What is the function of this protein?
Cleaves host elastin, collagen, IgG, and several complement components as well as endogenous pro-aminopeptidase (PubMed:11533066).  Autocatalyses processing of its pro-peptide (PubMed:9642203, PubMed:1744034).  Processes the pro-peptide of pro-chitin-binding protein (cbpD) (PubMed:9642203).  Involved in the pathogenesis of P. aeruginosa infections.
What are the official names of this protein?
Elastase, Neutral metalloproteinase, PAE, Pseudolysin.
What is the protein family that this protein belongs to?
Belongs to the peptidase M4 family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted in an Xcp-dependent fashion (a type II secretion pathway).
Protein: HFLD_IDILO
Sequence: MNEWQQRVIALAGMSLSAMAVQKLARSGELYPESISNTLVHSLLQQNPDNIEDIYGGLDNIKPGIQAFIRQAGSNKNKDIEVTRYLIGLIHLSRRLLKQPDILNLLGERITQVKRQKEEFEFENYRIQQSLAGIYRELISPLGQPIRINGNPEFLKRDSNQHHIRTLLLAGIRSAVLWQQVGGKRRHFVFSRKKMLDTAQQLLHVA
What are the official names of this protein?
High frequency lysogenization protein HflD homolog.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS33_ARATH
Sequence: MATQISKKRKFVADGVFYAELNEVLTRELAEDGYSGVEVRVTPMRTEIIIRATRTQNVLGEKGRRIRELTSLVQKRFKFPQDSVELYAEKVANRGLCAIAQAESLRYKLLGGLAVRRACYGVLRFVMESGAKGCEVIVSGKLRAARAKSMKFKDGYMVSSGQPTKEYIDAAVRHVLLRQGVLGLKVKIMLDWDPKGKQGPMTPLPDVVIIHTPKEDDVYIAPAQVVTQAAFVPEAPLTTTDYPAMPVA
What are the official names of this protein?
40S ribosomal protein S3-3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.