PharMolix/UniProtQA huggingface dataset:
Protein: SYGB_NATTJ
Sequence: MHNTLLFELGTEELPARFIPGLIKQLEENSANLLTEYRIEYENIKVMATPRRLTLLVNGLADKQQSSTTMKRGPAKEIAFDENGEPTKAAIGFARGQNIDPKDLEIREDNGKEYVYAVAEIVGENCQDVLPKLLDELITKFNLPVKMFWNNKQDKFLRPVRWLVCLFNDQVLPLNFGTVEASNISRGHRFLSQGDVIINSAENYEEVMRDSWVMVDHNVREETIKAQIEELADQMNASPEMPHDLLEEVNFLVEWPTALLGNFAEEFLEIPKEALITSMQEHQKYFALVDKEDSSKLLPYFVAVRNGDDHGIDKVKAGNERVLRARLSDARFFFEEDTKTSLESKREQLKSIIYKEQLGSVDQKVTRMEELGKTLLDILELSEPVRSLTLRAIALSKADLPTNMVSEFPHLQGIMGEKYARIHGEDEKVCLGISEHYLPRHTGDKLPQTMVGTITSIVDKVDNIASSFAIGERPSGSQDPYALRRQALGIVHIILETELAFSLEQLFHRALSLIPESALVAPISNILDDILDFVKLRSRTIFNEQGLPIDIIDSTLEVDKANVYKAYLRAKVLKDYRDSQELEDVRTAYTRVKNLANKAKGEDVYTELLQDETEKMLYHKYLNTEDKLLSDLEQDEISSAISELAGFKDYIDQFFDEVMVMVDDKHLQNNRLNLIYHIKEMYRQLADFSIIQD
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1634_LACDA
Sequence: MSKRPAFPGMGGMNMQQMMKQAKKLQEQMAQEQENITTQEFTGKAADDMVVATFTGDRTLKSLFIKPEAIDPDDPDMLEDLVIDAVNKGLKQIDQATQQSLGKYTKGLM
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Ldb1634.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: CING_XENLA
Sequence: MERDIYGDMADQHIPVGQGVQIRFIGDLKENGKPRGKRSKQDSYGVAVRVQGIDGQPFVVLNSGDKAKSSFGVQIKSQEPYLNASNTSPPNYQNYSSKPRGPSRSISSESELPENPYGSRGYRPSSSHYSSASDEEQKPRGNIRGSDGLSSLPRPLQASRREELRRSQSHSSLLEPDVEESYDYDHHYSERSSTLDTTYSQSSRDSAWSRSSQKKIDNGDYPSLGYRSATSQQSTSVSNKTKKNGLSTSSPSNQSNEDIDTKPLSSVDSLINKFDIKGQVRGRTARRSQALKDERKRSQSLDGRKNYHDTADSREIIVEKQNEVQTMREPVNASNRSFNRQTLERGDISKTRLTKEWLDQDREEPVILKQQRTVQSEFQLKSTPDLLRDQQPDGSDPTREMIFGILREGSLESENTLRKKTSILLEKLPSLQVQPGEDTISLGSQKKELERKVAELQRQLDDEMKQRMKLETSQGRPKAGMQRLEIELEESKEECSRLKELYEKKKNELSAMSQELMEVRMGKEQVETKLRTMEDKLMDSKEELSHLRAKGGTSPDKLALLKELEEVQDELDEVLQIRQKQEELLRQKDRELTALKGALKDEVANHDKDLDRVREQYQNDMQQLRKNMDNVSQDQLSLESERQKINQVVRNLQRELEESSDEISQWKEMFQKNKEELRSTKQELLQMKLEKEESEDELKETRDRFSLLQSELAQVKKGSVDPGEVASVRKELQRVQDQLKQLSVDKQKVEENLQQREREMSALKGTLKEEVSGRDRETVRLREQLQSEVMHVKKENEGLAKESRRIQDQLKQVLLEKQRHEETVHQRERELSVLKGALKDEVSGRDRETEKLRERLEQDALMTKRSYEELVKINKRLESEKTDLERVRQVIENNLQESREENDDLRRKILGLEAQLKETNTFCDDLQRAESRLKDKINKLEAERKRMEDSLGEVADQEQELAFVKRDLESKLDEAQRSLKRLSLEYEELQECYQEEMKQKDHLKKTKNELEEQKRLLDKSMDKLTRELDNMSNESRGSLQLLQTQLEEYREKSRKEIGEAQKQAKEKTAEAERHQFNSSRMQEEVQKLKLALQELQVEKETVELDKQMISQRLQSLEQDIESKKRVQDDRSRQVKVLEDKLKRMEAELDEEKNTVELLTDRVNRSRDQMEQQRAELNQERSRGQDLECDKISLERQNKELKNRLASMEGQQKPSVNVSHLEAKLQEIQERLQLEEREKATLLSTNRKLERKLKELNIQLEDERLQVNDQKDQLNLRVKALKRQVDEAEEEIERLEGLRKKAVREMEEQQEINEQLQTRVKVMEKESKRKPIRPAHDDDLSSDGEFGGPYDPSSITSLLTESNLQTSSC
What is the function of this protein?
Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier, possibly by linking ZO proteins to the actomyosin cytoskeleton.
What are the official names of this protein?
Cingulin.
What is the protein family that this protein belongs to?
Belongs to the cingulin family.
What are the subcellular locations of this protein?
Cell junction, tight junction. Note=Localizes to the apical junction complex composed of tight and adherens junctions.
Protein: LPXD_CHLTE
Sequence: MKIADIKAFLGRYFDPVELVGTGDIEIVGPAKIEEASTGHVSFVANEKYYRYIAQTGASLVIVSQKAPLDDASPGTSFLKVADPYTAFVFILQHFSGKRRIADTGIAASASVAASVRLGENVSLGEHVVIGENCVIGDGTVIGPGTVLMDGVTVGSGCTIFPLVTIYDGTVIGDRVTIHSGTVVGADGFGFAPQKDGSYIKIPQMGTVEIGDDVEIGANTTIDRATMGATVIEKGAKIDNLVQIAHNCRIGGDTVIASQAGISGSVKIGRQCLIGGQAGFAGHLELADRTSVAAKAGISKSFLEPGLAIRGVPAQPMRDQLRQEAQVRGLGEMKSKLEALEAKLLALQQQLGE
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: CHEB2_VIBVY
Sequence: MMSKKMKVLVVDDSPVFRALLSEIINSDPQLEVIGAAEDPYQAREMIKALKPDVLTLDIEMPKMNGVQFLKNLMRLHPLPVVMISTLTQHGADATLMALELGAVDYFPKPSVANTADMLGYRSLVNEKIRMAAQAQVGANQSMSPAVASSSAVSTSQYQLIAIGASTGGTEAVKHLLSALPASMPPIVITQHISAMFSGPFASRLDASCALSVSELTQGEVALKANHAYVAPGDKHLMVFRRGGQLYAHLDDSPAVNRHKPSVDVMFGSVAESLKGKAIGVILTGMGKDGAQGMLQMKQQGAITVAQDEQSCVVYGMPRAAVECGAAMHIKPLNKLPQFLCDLLS
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 2.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSB_SHEDO
Sequence: MKVTLLIPARFGSSRFPGKPLAPINGKPMIQHVYERASLAKGLDAIYVATDDDRIKDAVEAFGGKVVMTSAAAASGTDRINDAIEQLGLSDDDLVINLQGDQPLIDPISIEQIVSLFERHPGEFEMATLGFEITDKSELDDPMHVKMVFDNDFNALYFSRARIPFGRDTNDYPVYKHLGVYAYTKRFVNAFAKLPLGKLEDLEKLEQLRALEYGHKIKVAISAFDSPEVDTPEDIRKCEQRLAVD
What is the function of this protein?
Activates KDO8N (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in the Shewanella genus.
What are the official names of this protein?
8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase, CMP-8-amino-3,8-dideoxy-manno-octulosonate synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y025_BORGP
Sequence: MSGHSKWSTIKRKKGALDAKRNKIFTKLIREITIAAKIGGGDVESNPRLRVAVNKAKVANMPKDNIEKAIKKGIGGNEGVEYFEITYEAYAPYGVALMIKCLTDNKNRTSSDVKSVLAKGGGSLGTPGSVSYMFYRKGLIVYNLEKYLEDEIMEFALEAGVEDILVSNNEAEVITSPDDFDKVLSFLKTKFKEEMAEVALIPENKISLNKEQAEKIILLIEKLEDFDDVQEVIHNLEIPEELS
What are the official names of this protein?
Probable transcriptional regulatory protein BG0025.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGA_STRMU
Sequence: MKILFVAAEGAPFAKTGGLGDVIGALPKSLVKNNNEVSVILPYYDVVDAKFGDQIEDLFYFFTNVGWRREYVGIKHIFRDGVDFYFIDNKHYFYRGQIYGEFDDGERFAYFQLAALEAMEKIQFIPDILHVHDYHTAMIPYLLKEKYHWINAYHGIKTVFTIHNIEFQGQFNPSMLGELFGVGDERYRDGTLRWNDCLNWMKAAVLYADRVTTVSPSYAKEIMTPEFGKGLDQIMRMESGKLSGVVNGIDTDLFDPETDPHLAVHFSKDDLSGKAKNKAALQERVGLPVREDVPLVGIVSRLTDQKGFQLVVDQLNTMMQLDLQIVLLGTGYADFENAFAWFGHAYPDKMSANITFDLELAQQIYAASDIFLMPSAFEPCGLSQMMAMRYGTLPLVHEVGGLRDTVIPYNEFEKTGTGFGFQDFSGYWLTKTLEAALDVYYNRKEDWKILQKNAMTTDFSWDTASQSYEHLYKELA
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: XYLD_CAUVC
Sequence: MRSALSNRTPRRFRSRDWFDNPDHIDMTALYLERFMNYGITPEELRSGKPIIGIAQTGSDISPCNRIHLDLVQRVRDGIRDAGGIPMEFPVHPIFENCRRPTAALDRNLSYLGLVETLHGYPIDAVVLTTGCDKTTPAGIMAATTVNIPAIVLSGGPMLDGWHENELVGSGTVIWRSRRKLAAGEITEEEFIDRAASSAPSAGHCNTMGTASTMNAVAEALGLSLTGCAAIPAPYRERGQMAYKTGQRIVDLAYDDVKPLDILTKQAFENAIALVAAAGGSTNAQPHIVAMARHAGVEITADDWRAAYDIPLIVNMQPAGKYLGERFHRAGGAPAVLWELLQQGRLHGDVLTVTGKTMSENLQGRETSDREVIFPYHEPLAEKAGFLVLKGNLFDFAIMKSSVIGEEFRKRYLSQPGQEGVFEARAIVFDGSDDYHKRINDPALEIDERCILVIRGAGPIGWPGSAEVVNMQPPDHLLKKGIMSLPTLGDGRQSGTADSPSILNASPESAIGGGLSWLRTGDTIRIDLNTGRCDALVDEATIAARKQDGIPAVPATMTPWQEIYRAHASQLDTGGVLEFAVKYQDLAAKLPRHNH
What is the function of this protein?
Catalyzes the dehydration of D-xylonate to 2-dehydro-3-deoxy-D-arabinonate during D-xylose degradation.  Can also dehydrate D-gluconate, with similar catalytic efficiency.  Has weak activity with D-galactonate, D-fuconate and L-arabinonate.
What are the official names of this protein?
D-xylonate dehydratase, XyDHT, Gluconate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: RUVA_GEOSW
Sequence: MIEFVRGYVDYVCPEYIVIDNNGIGYQIFTPNPFSFQESRDTIVTVYTYQYVREDTLALYGFRTREERTLFAKLLQVSGIGPKGGLAILAAGQPEQLVEAIEQENETFLCKFPGVGKKTARQMILDLKGKLTAVTAKTFPDLFHLQEESARPHLSALEEAIEALKALGYAEREIQKVVPSLMKENLSTDQYVKRALQQLLK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: TRMD_CLOBL
Sequence: MRIDVLTLFPEMFSIFNHSIIGRAIEKEILKINTVNIRDYTIDKHKKVDDYPYGGGAGMVMAAQPIVDSIKTVKKENKGKVIFLGPKGKTFNQNLAKELAKEEELIFLCGHYEGIDERAYEYIDMEISLGDFVLTGGEMACIPIVDSICRLVDGVLKSSESYEDESFYNGLLEYPQYTRPATYEGKSVPEVLLSGHHENIKKWRKAKSLIITNKVRPDLFKKYKLTEEDKKILKDFNKKL
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_LEUMM
Sequence: MIEFEKPNIHNIEEDARYGKFVVEPLERGYGTTLGNSLRRILLSSLPGAAVNTVQIDGVVHEFSTVDGVVEDVTQIILNLKKVVLAIDSDDERSLEIDIQGPADVTAADLQGGADVEVLNPDLHIATVAAGKSLHMTVTAVKGRGYTSADENKKLRDEMPIGVLAVDSIYTPIERVNYQVENTRIGARDDYDKLTFDIWTNGSIKPSDALSLGAKILAEHLGLFMDISPVAAEASVMVEAEPVAASASDSAPIEDLDLSVRSYNCLKRAGINTIVELTDRTEADMMKVRNLGRKSLDEIQEKLTDMNLGFRKED
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: RPOY_LYSSC
Sequence: MIYKVYYQENANEIPVRENTKSLYLEAASEREVRQKLKDRNYNIEFVQLLEGNYLEYEQASPNFVLEEI
What is the function of this protein?
A non-essential component of RNA polymerase (RNAP).
What are the official names of this protein?
DNA-directed RNA polymerase subunit epsilon, RNAP epsilon subunit, RNA polymerase epsilon subunit, Transcriptase subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit epsilon family.
Protein: HSLU_ECOLU
Sequence: MSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAKNNWGQTEQQQEPSAARQAFRKKLREGQLDDKEIEIDLAAAPMGVEIMAPPGMEEMTSQLQSMFQNLGGQKQKARKLKIKDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKRGESSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLERLMEEISYDASDLSGQTITIDADYVSKHLDALVADEDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Heat shock protein HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NACA_PHANO
Sequence: MSNPRIEELPDEPEKKNVQIEEDESSDESEGEEGEANIPAGASVAVHSRNEKKARKAIAKLGLKHIDGITRVTLRRPKNILFVINQPDVYKSPSSNTWIIFGEAKIEDLNSQAQASAAQQLAQAEAASHDHSGHDHDHDHKGKGKAVEDKKDDEEDEEEEEEDDEEVDDSGLEAKDIELVMQQASVSRKKAVKALKENDNDIVNSIMALSI
What is the function of this protein?
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting.  The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum.  EGD2 may also be involved in transcription regulation (By similarity).
What are the official names of this protein?
Nascent polypeptide-associated complex subunit alpha, NAC-alpha, Alpha-NAC.
What is the protein family that this protein belongs to?
Belongs to the NAC-alpha family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic, may also transiently localize to the nucleus.
Protein: UGPC_CUPPJ
Sequence: MAKLSLRNVQKTYAGNVKVVHGIDMEIADGEFIVIVGPSGCGKSTLLRMVAGLETITGGDIHIGDRVVNNLEPAERDIAMVFQNYALYPHMSVYDNMAYGLKIRGMAKAEIEQRVKHAAGILELAPLLDRKPRQLSGGQRQRVAMGRAIVREPSVFLFDEPLSNLDAKLRVQMRLELKELHRRLGTTSLYVTHDQVEAMTLADRMMVLNGGRVEQIGTPLEVYTRPASTFVAGFIGSPPMNLVPVARNGGMAGAGGVAQMRVLGKEGGASDATLGHLPMGLHLPAEALLGLRPEHIEPCAAHDAIAEVDVRVVEALGADSFAYGSLGGQPIVVRLDSHARVRAGDKLPVTSSPDHLHFFDAQSGKRIEA
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
sn-glycerol-3-phosphate import ATP-binding protein UgpC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. sn-glycerol-3-phosphate importer (TC 3.A.1.1.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SYIM_MOUSE
Sequence: MHWGLCPRGPGAAAVAAAGSFWGPARLPSRLGCLGMTRRLVVRSVAGADSPQSSSKGGRYRDTVLLPQTSFPMKLLGRQQSDMELEIQQKCGFSELYSWQRERKVKTEFCLHDGPPYANGDPHVGHALNKILKDIANRFHMMRGSKVHFVPGWDCHGLPIETKVLSELGVDAQSLSAMEIREKARSFAQAAIEKQKSAFVRWGVMADWNNCYYTFDPKYEAKQLRVFYQMYEKGLVYRSYKPVYWSPSSRTALAEAELEYNPEHVSRSIYVRFPLLRPPPKLESLTDASSPVSVLVWTTQPWTIPANQAICYMPEAKYAVVKCSASGHLYILAEDKIAPVASALETTFDVVAAFSGVDLEGGTCSHPLTPDKVSPLLPATHVTMAKGTGLVHTAPAHGMEDYSVASQHSLPMDCLVDEGGMFTDAAGPELQNKAVLKEGTDVVIKMLQATKNVLKEENIVHSYPCDWRTKTPVLIRASKQWFVNITDIKAAAKESLKTVKFIPGAALNSMTDMLDRRPYWCISRQRVWGVPIPVFHHKTKDEYLINSQTTEHIIKLVEQHGSDVWWTLPAEQLLPAEVLAQAGGPGALEYAPGQDILDIWFDSGTSWSCVLQDTQQRADLYLEGKDQLGGWFQSSLLTSVATRSKAPFRTVMVHGFTLGEKGEKMSKSLGNVINPDTIISGGKDHSKEPPYGADILRWWIAESNVFTEVTIGPSVLSAARDDISKLRNTLRFLLGNLTGFNPETDSVPVKNMYVIDQYMLHLIQDFATKITDSYKQYDFGKVVRLLKAFYTRELSSFYFSIVKDRLYCENEKDPKRRSCQTALAEILDVLVRAFAPILPHLAEEVFQHIPYVTEPKSVFRTGWINTSSIWKKPGLEEAVESACAMRDSFLGSIPGKNAAEYEVIIVIEPGLLFEIMEMLQAEETSSTSQLNELMMASQTTLLAQEPRERTAGDIELTGTFVINLEGGDIREESSYKVIVVPTAREKCPRCWKHTSETADALCPRCAEVIGAK
What are the official names of this protein?
Isoleucine--tRNA ligase, mitochondrial, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: HTPG_GEOMG
Sequence: MTKTTKKFETEVQQLLDLVIHSLYSNKDIFLRELISNSSDAIDKVLFEAHQNAAVIEGEPEGKIKLIPDKEAGTITIRDNGVGMTMEEVEKNIGTIAHSGTKAFLANLKEQNVSEHPELIGQFGVGFYASFMVADRVTLVTRRAGQDKAAGVRWESTGDGTYTVEEAVKETRGTEITLHLKEEMKEYLDEWKIRSIVRKYSDYVQYPVVMDVTRTEVPKGVNGEEIEGAGTIEKTVEETLNSMKAIWARAKSEVTEEEYEEFYKHVSHDFEKPLKTIHYSAEGVSEFKALLYLPAHKPFDLFMPERKKGVQLYVRRVFITDSCEQLIPDYLRFVKGVVDSSDLPLNVSREILQEDVQIKRIQKSLVSKIISTLSEMREKEADDYLAFYKEFGQVLKEGVHFDYANREKLQDLLLFESTRTEAGKFTSLKEYVERMPAGQEEIYFITGTSRTALEQSPHLEIFRKKEYEVLFLTDPVDEWVVQGVTEYDGKKLKAVDRGDVIPATEEEKKEQEAKREEAFKQYGDLLSFVKEKLDARVKEVRLSSRLTDSACCLVADEHGLNANMERILRAMNQDVPESKRILELNPDHPLMQVMANLFARDKANPRLGDYCDLLYDQALLTEGSPISDPLRFTRLVAELMVADGKAAAGE
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE2_CERS5
Sequence: MSAASEKPVVTRFAPSPTGYLHIGGARTALFNWLFARGRKGTFLLRIEDTDRERSTPEATDAILRGLTWLGLDWDGEVVSQFARKDRHAEVAREMLARGAAYKCFSTQDEIEAFREAARAEGRSTLFRSPWREADPSTHPDAPYVIRMKAPRTGETVIADRVQGTVRFQNETLDDMVVLRSDGTPTYMLAVVVDDHDMGVTHVIRGDDHLNNAARQTMVYEAMGWEVPIWAHIPLIHGPDGKKLSKRHGALGVEEYQAMGYPAAGMRNYLTRLGWAHGDDEFFTSEQAMAWFDLEGIGRSPARLDFKKLENVCGQHIAVMDDAAAMHEIQAYLAAARKPALTDLQAGRLSAALYALKDRAKTFPELLEKARFALESRPIAADDAAAKALDAVSRGILRELTPILQTASWSKQELEAALTAFAGEKGMGFGKLAGPLRAALAGRTVTPSVFDMMLVIGRDETIARLEDAAAA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 2, Glutamyl-tRNA synthetase 2, GluRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STAC3_DANRE
Sequence: MAQYDQLEDKDSLDIHDNPPAPENVVKEDDNTVYFVYDEEVEEEEAPPPPTPEPIVQVNDKPHKFKDHYCKKPKFCDVCARMIVLNNKFALRCKNCKTNIHHSCQSYVQFQRCFGKIPPGFRRAYSSPLYDQEINNPGQQNRTDPVFDTLRVGVIMANKERKKGSEDKKNMMMMMMEEEEAQQPKEDEEGAEGKQDGDKKDKTATDDKNKKQQQTFSQSHYYMALYRFKAIEKDDLDFHPGDRITVLDDSNEEWWRGKIGEKTGYLPMTYIIRVRAGERVYKVTRSFVGNREMGQITLKKDQIVVKKGEEVNGYLKVSTGRKLGFFPADLLHEL
What is the function of this protein?
Required for normal excitation-contraction coupling in skeletal muscle and for normal muscle contraction in response to membrane depolarization (PubMed:23736855).  Required for normal Ca(2+) release from the sarcplasmic reticulum, which ultimately leads to muscle contraction.  Probably functions via its effects on muscle calcium channels.  Increases CACNA1S channel activity, in addition to its role in enhancing the expression of CACNA1S at the cell membrane.  Has a redundant role in promoting the expression of the calcium channel CACNA1S at the cell membrane (By similarity).
What are the official names of this protein?
SH3 and cysteine-rich domain-containing protein 3.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Cell membrane, sarcolemma, T-tubule.
Protein: KGUA_HYDCU
Sequence: MAGSLYIISAPSGAGKTSLVSKLTEKDSRIQVSISSTTRPKRPGEEDGVNYVFLSVDAFKQKVAENDFLEHAQVFDNYYGTSKSVVESKLAEDKDVILEIDWQGAQQVRKLIPDAVSVFILPPSLKELEKRLRGRGTDSEDVIERRMSDAVNEMKHFNEFDYLVINNHFDTALSELHSIFLANRQACAKQYEKHSVMINELTQQH
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTCB_EUBLI
Sequence: MIRNSLTDVFFAKDDVENLHEGVLRVLSKVGVKIENDEALGIFEQHGARVENGTVYIGEVLLNKALQTVPANFELQGFDRTVQVGLDHDPVVIPTNGTPMVLNFDGSYSDTNTDDLVNFYKLIDTSDVMQVTSEIAVDVPGLDKTKDSLLAQTALLMKYSHKPIYNILGATIHNYKKGSVAQGVRENIQFAKKYYGYDDKYVIYSGTCVISPLGVGWEAMDHFMGFIKENQPISITACSMTNLTAPGSLYGSVVEDAAAILSIVVLSQLMNPGLPVLYTSLSSMSDMRYVQLCMGAPEFALITLGHIALANFYKIPVRVGGALGDAFKADYQAGVESFVGLMAPMLSQSAMIPHGCGTMGSFNLTSYEKFIMDEETIRYLMRLRRGFEVSDKRKEKALKDITKVGPRGNFLGGRTPKEYREDNYLASEVFNRKGCKENTREEQGDIRDRARKVYDARMEAYELPDTTLEQKKLLNTELPEQYKFDI
What is the function of this protein?
Involved in the degradation of the quaternary amine L-carnitine (PubMed:32571881).  Component of a corrinoid-dependent methyltransferase system that transfers a methyl group from L-carnitine to tetrahydrofolate (THF), forming methyl-THF, a key intermediate in the Wood-Ljungdahl acetogenesis pathway (PubMed:32571881).  MtcB catalyzes the methylation of the corrinoid protein MtqC, using L-carnitine as the methyl donor (PubMed:32571881).  L-carnitine demethylation generates the unusual biological product norcarnitine, which is likely degraded by other members of the gut microbiota (PubMed:32571881).  In vitro, can methylate free cob(I)alamin (PubMed:32571881).
What are the official names of this protein?
L-carnitine:corrinoid methyltransferase, Cobalamin-dependent carnitine demethylase, L-carnitine methyltransferase, L-carnitine--corrinoid protein Co-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the trimethylamine methyltransferase family.
Protein: WECF_SALA4
Sequence: MTVLIHVLGSDIPHHNHTVLRFFNDTLAATSEHAREFMVAGEDNGFTESCPALSLRFYGSKKALAQAVIAKAKANRRQRFFFHGQFNTSLWLALLSGGIKPAQFYWHIWGADLYEVSHGLKFRLFYPLRRIAQGRVGGVFATRGDLSYFARQHPGVRGELLYFPTRMDPSLNAMAKERQRAGKLTILVGNSGDRSNQHIAALRAVYQQFGDTVNVVVPMGYPANNQAYIDEVRQAGLALFSAENLQILSEKMEFDTYLALLRQCDLGYFIFARQQGIGTLCLLIQADIPCVLNRDNPFWQDMAEQHLPVLFTTDDLNEQVVREAQRQLASVDKSGITFFSPNYLQPWHNALRIAAGEAE
What is the function of this protein?
Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis.
What are the official names of this protein?
TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase, 4-alpha-L-fucosyltransferase, TDP-Fuc4NAc:lipid II Fuc4NAc transferase, Fuc4NAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 56 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TRPF_STRPN
Sequence: MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAELAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQVDGNGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQHFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: FAB1A_DANRE
Sequence: MAFTGKYQLESHENFEAFMKAVGVPDDEVEKGKDIKSISEIHQDGKDFKVTVTAGTKVILYSFTVGEECELETFTGDRAKTVVQMDGNKLTAFVKGIESVTELDGDTISNTLSFNGIVYKRISRRIS
What is the function of this protein?
Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm.  May be involved in intracellular lipid transport (By similarity).
What are the official names of this protein?
Fatty acid binding protein 1-A, liver.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Cytoplasm.