PharMolix/UniProtQA huggingface dataset:
Protein: ANR27_HUMAN
Sequence: MALYDEDLLKNPFYLALQKCRPDLCSKVAQIHGIVLVPCKGSLSSSIQSTCQFESYILIPVEEHFQTLNGKDVFIQGNRIKLGAGFACLLSVPILFEETFYNEKEESFSILCIAHPLEKRESSEEPLAPSDPFSLKTIEDVREFLGRHSERFDRNIASFHRTFRECERKSLRHHIDSANALYTKCLQQLLRDSHLKMLAKQEAQMNLMKQAVEIYVHHEIYNLIFKYVGTMEASEDAAFNKITRSLQDLQQKDIGVKPEFSFNIPRAKRELAQLNKCTSPQQKLVCLRKVVQLITQSPSQRVNLETMCADDLLSVLLYLLVKTEIPNWMANLSYIKNFRFSSLAKDELGYCLTSFEAAIEYIRQGSLSAKPPESEGFGDRLFLKQRMSLLSQMTSSPTDCLFKHIASGNQKEVERLLSQEDHDKDTVQKMCHPLCFCDDCEKLVSGRLNDPSVVTPFSRDDRGHTPLHVAAVCGQASLIDLLVSKGAMVNATDYHGATPLHLACQKGYQSVTLLLLHYKASAEVQDNNGNTPLHLACTYGHEDCVKALVYYDVESCRLDIGNEKGDTPLHIAARWGYQGVIETLLQNGASTEIQNRLKETPLKCALNSKILSVMEAYHLSFERRQKSSEAPVQSPQRSVDSISQESSTSSFSSMSASSRQEETKKDYREVEKLLRAVADGDLEMVRYLLEWTEEDLEDAEDTVSAADPEFCHPLCQCPKCAPAQKRLAKVPASGLGVNVTSQDGSSPLHVAALHGRADLIPLLLKHGANAGARNADQAVPLHLACQQGHFQVVKCLLDSNAKPNKKDLSGNTPLIYACSGGHHELVALLLQHGASINASNNKGNTALHEAVIEKHVFVVELLLLHGASVQVLNKRQRTAVDCAEQNSKIMELLQVVPSCVASLDDVAETDRKEYVTVKIRKKWNSKLYDLPDEPFTRQFYFVHSAGQFKGKTSREIMARDRSVPNLTEGSLHEPGRQSVTLRQNNLPAQSGSHAAEKGNSDWPERPGLTQTGPGHRRMLRRHTVEDAVVSQGPEAAGPLSTPQEVSASRS
What is the function of this protein?
May be a guanine exchange factor (GEF) for Rab21, Rab32 and Rab38 and regulate endosome dynamics (PubMed:16525121, PubMed:18477474).  May regulate the participation of VAMP7 in membrane fusion events; in vitro inhibits VAMP7-mediated SNARE complex formation by trapping VAMP7 in a closed, fusogenically inactive conformation (PubMed:23104059).  Involved in peripheral melanosomal distribution of TYRP1 in melanocytes; the function, which probably is implicating vesicle-trafficking, includes cooperation with Rab32, Rab38 and VAMP7 (By similarity).  Involved in the regulation of neurite growth; the function seems to require its GEF activity, probably towards Rab21, and VAMP7 but not Rab32/38 (By similarity).  Proposed to be involved in Golgi sorting of VAMP7 and transport of VAMP7 vesicles to the cell surface; the function seems to implicate kinesin heavy chain isoform 5 proteins, GOLGA4, RAB21 and MACF1 (PubMed:22705394).  Required for the colocalization of VAMP7 and Rab21, probably on TGN sites (PubMed:19745841).  Involved in GLUT1 endosome-to-plasma membrane trafficking; the function is dependent of association with VPS29 (PubMed:24856514).  Regulates the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes (By similarity).
What are the official names of this protein?
Ankyrin repeat domain-containing protein 27, VPS9 domain-containing protein.
What are the subcellular locations of this protein?
Early endosome. Late endosome. Cytoplasmic vesicle membrane. Lysosome. Cell membrane. Melanosome. Note=Colocalizes with VAMP7 in transport vesicles in the shaft of hippocampal neurons (By similarity).
Protein: PYRR_AKKM8
Sequence: MTPPSQEIVLDGPGISRALERMAHGIVARFPGEPLAIVGLLSQGDVIARRLVDKVKELGVEAQYGSIDISLYRDDIFKLEARPSLRSSNLPFSTDDMRVVLVDDVLYTGRTIRAALNALFDYGRPARIELACLIDRGGREVPIQPDYTGHVLDHAGAKVIVSMKEADGEDSVVIPSH
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: PDXJ_VIBVU
Sequence: MSSIYLGVNIDHVATLRNARGTKYPDPVHAAEVAERAGADGITIHLREDRRHITDRDVRILRETLQTRMNLEMAVTDEMIEIALKTQPEYVCLVPEKREELTTEGGLDVAGHLDKIKAATEKLTAAGIKVSLFIDADREQIDAAKACGAPFIELHTGHYADAATEADQLDELKKIAAGASYAADLGITVNAGHGLTYHNVAPIAALPEIYELNIGHAIIGRAVFDGLHKAVADMKAIMVAARQ
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_VIBVU
Sequence: MANNVVVLGTQWGDEGKGKIVDLLTEDAKYVVRYQGGHNAGHTLVIDGVKTVLHLIPSGILRDNVKCVIGNGVVLSPEALIKEMKPLEERGIPVRERLFISEACPLILPYHVAMDQAREIARGKKAIGTTGRGIGPAYEDKVARRGLRVGDLFDMEAFAEKLKEVMEFHNFQLVNFYKAEAVSYEEVLEQARGYAELLTSMVIDVTDELDAARKRGDKIMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVAAGSGFGPRYLGYILGIAKAYCTRVGAGPFPTELYDGQEKQDPVGKHLGTVGHEFGATTGRLRRTGWFDAVAMRRAIQINSVSGFCLTKLDVLDGLKELKICTGYQMEDGSVLEVSPMAAEAFEKVTPIYETMPGWSENTFGAKSLEDLPQAAINYIKRIEELTGVPVDIISTGPDRNETIVKVHPFES
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ITIH1_MESAU
Sequence: MDGAAVGLRVLLGLGLVSLLTLEAMPAAWGLATTGRPRAREKRQAVDTTPDGVLVKSLKVNCKVTSRFAHYIITSQVVNRQPNEAREVAFDVEIPKTAFISDFAITADGNTFIGDIKDKASAWKQYRKAISGENAGLVRTSGRNMEQFTIHITVGAQSKATFQLTYEEVLKRRLTQYDIVIKVKPKQLVQHFEIDVDIFEPQGISKLDAQASFLSKELAAQTIKESFSGKKGHVLFRPTVSQQQQPCPTCSTSWLNGDFKVTYDVNRDKLCDLLVANNYFAHFFAPKNLTNMSKNLVFVIDISGSMEGQKVKQTKEALLKILGDVKPGDSFDLVLFGSRVQSWKGSLVPATQANLQAAQDFVRRFSLAGATNLNGGLLRGIEILNKAQGSHPELSSPASILIMLTDGEPTEGETDRSQILKNVRNAIRGRFPLYNLGFGHDLDFNFLEVMSMENSGWAQRIYEDHDATQQLQGFYNQVANPLLTDVELQYPQDSVLSLTQHRHKQYYDGSEIVVAGRIADHKLSTFKADVRARGERQEFKATCLVDEEEMKKLLRERGHMLENHVERLWAYLTIQELLAKRMKMEGEERANLSSQALKMSLDYQFVTPLTSMTIRGLTDEDGLEPTIDKTPEDSQPLVKVGPRRTFVLSATQPSPTARSSVVSKLPNQVTGVDTDPHFIIYVPQKEDSLCFNINEEPGVILSLVQDPDTGFSVNGQLIGSKPSRPGQHEATYFGRLGISNPPSDFQLEVTPRNITLNPSSGGPVFSWRDQATPQKDGVLVTINKKRNLVVSVEDGATFEIVLHRTWKGSAAHQDFLGFYVLDSSRMSARTRGLLGQFFCPLDFEVSDIRPGSDPMKLDATMRVKNRQLAVTRGLQRDYSKDPRHGTEVSCWFIHNNGAGLIDGVHTDYIVPDIF
What is the function of this protein?
May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.
What are the official names of this protein?
Inter-alpha-trypsin inhibitor heavy chain H1, ITI heavy chain H1, ITI-HC1, Inter-alpha-inhibitor heavy chain 1.
What is the protein family that this protein belongs to?
Belongs to the ITIH family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPL_ECO55
Sequence: MENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPDLIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IRAG2_HUMAN
Sequence: MESTPFSGVANQIHTLCERPTYGEVKDGALDVKRQHKCPGPTSGPSPGTNLSGCIRMNDDPSMEENGVERVCPESLLQSREYSSLPLPRHTSSTDGTITSSDPGLEILNMASCDLDRNSLCKKEEDTRSASPTIEAQGTSPAHDNIAFQDSTSKDKTILNLEAKEEPETIEEHKKEHASGDSVVSPLPVTTVKSVNLRQSENTSANEKEVEAEFLRLSLGFKCDWFTLEKRVKLEERSRDLAEENLKKEITNCLKLLESLTPLCEDDNQAQEIIKKLEKSIKFLSQCAARVASRAEMLGAINQESRVSKAVEVMIQHVENLKRMYAKEHAELEELKQVLLQNERSFNPLEDDDDCQIKKRSASLNSKPSSLRRVTIASLPRNIGNAGMVAGMENNDRFSRRSSSWRILGSKQSEHRPSLPRFISTYSWADAEEEKCELKTKDDSEPSGEETVERTRKPSLSEKKNNPSKWDVSSVYDTIASWATNLKSSIRKANKALWLSIAFIVLFAALMSFLTGQLFQKSVDAAPTQQEDSWTSLEHILWPFTRLRHNGPPPV
What is the function of this protein?
Plays a role in the delivery of peptides to major histocompatibility complex (MHC) class I molecules; this occurs in a transporter associated with antigen processing (TAP)-independent manner.  May play a role in taste signal transduction via ITPR3.  May play a role during fertilization in pronucleus congression and fusion.  Plays a role in maintaining nuclear shape, maybe as a component of the LINC complex and through interaction with microtubules.
What are the official names of this protein?
Inositol 1,4,5-triphosphate receptor associated 2, Lymphoid-restricted membrane protein, Protein Jaw1.
What is the protein family that this protein belongs to?
Belongs to the IRAG2 family.
What are the subcellular locations of this protein?
[Processed inositol 1,4,5-triphosphate receptor associated 2]: Cytoplasm. SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Nucleus envelope. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Chromosome. Note=Colocalized with ITPR3 on the endoplasmic reticulum membrane.
Protein: RSMG_BACP2
Sequence: MNIEQFTAALEEKGITLSPVQLEQFETYFRMLVEWNEKMNLTSITEKEEVYLKHFYDSISASFFIDFHKVTTICDIGAGAGFPSIPLKICFPHLHVTIVDSLQKRITFLNELAKGLNLQDTTFYHDRAETFGQRKEKRESYDLVTARAVARLSVLSELCLPLVKKEGLFVALKASAADEEMQAGKKAVTVLGGEVVEKHSFVLPLEESERNIIVIEKKKQTPKKYPRKPGTPNKSPIEG
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RCF1_USTMA
Sequence: MSGMPNAELVREQQQPGDPMGSSAHPNAYVPEVGGLGSELPEAPRDKFFRKMREQPLVPIGSLLTCGALIAASNHLRSGNRDQFNKALRWRVGFQGLTVLAALVGSFYYGQQAAATIPAPASSSADAPLQQGAVTTLPGRAPTVWQQTRADERANKGRNEFEGRVGQALDRELNDDKRLEEALLGKEEEINLEQLKKTATKPRPVIGQDARRQV
What is the function of this protein?
Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes.
What are the official names of this protein?
Respiratory supercomplex factor 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RCF1 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: RL35_CALBD
Sequence: MPKLKTHRGLAKRIKISGSGKYLRKKAGKSHLLSGKSRKRKRNLKKTVVVDATNVKAVKKLLPYL
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: DER_UREU1
Sequence: MRTIAIVGKPNVGKSSLFNRILMRRKSIVDDQPGVTRDRIYDVGNWLTRDFMLIDTGGIISSEDTYQDNINEQVLFAINEANTIIFLVSAKDGINNDDKKIAKMLKEKAKDKKVILVVNKVESEKYYFNEGELYSFGFGKFFKISAEHGIGMGDLLDELVKDMPIQNALDQQERFKFCIIGRPNVGKSSLTNTILGEQRMIVNAEAGSTRDSIDNDFSYHNKKYTIIDTAGVRRKGKIVEAVEKYAVLRTQKAIERSQLILLVLDGSEPFKEQDEVVGGLAYDANIPTIIVVNKWDNIVNKNSHTMEMVKKQIRSQFKYLSWAPIVFISALDNKRIHTIFETIELVREQAMRKVATSLLNDVVIKANAFQEPPPFKGGRISISYVVQVQSQIPTFVLKCNNPKFLHFSYARYIENEIRKAFGFDSVPITLYWQDKNKKLRGE
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: INR1L_CARAU
Sequence: MSKHAVVQFGVVYALLFPGVFGFVPSPTNVSVVCHNFVNVLYWNYSNPTEQTKFAIKVEPYESPSQTVDTSQTYLDISSYSTDVEDDYLVLLTAHDGQEKSEDVSIRFTYSKDYFDENKHKYKCSLDFPAVNTSVHKDVIEVSFQHPFKLYKQEIMKEEFTYKITHDEQMVKYSCFEDEDLCNAEVHFNQSVAGQCVELKLEGVIAGIPSYTYSNVCVPQPTPETDKTGIIAALIGGATVVLFIIMGFVWLLWRKWSNIPQMPQGLWCIISKQSHTMLLSQPEPTDICPVTSQGPLNYLTEEDQSVSARDDTGADPPVVSEEGMAGEDSQGLGCSSDYDRPKFL
What is the function of this protein?
Receptor which shows binding specificity for the cytokine ifng1 (interferon gamma 1).
What are the official names of this protein?
Interferon gamma receptor 1-like, Interferon gamma receptor 1-2.
What is the protein family that this protein belongs to?
Belongs to the type II cytokine receptor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: STBB_ECOLX
Sequence: MMDKRRTIAFKLNPDVNQTDKIVCDTLDSIPQGERSRLNRAALTAGLALYRQDPRTPFLLCELLTKETTFSDIVNILRSLFPKEMADFNSSIVTQSSSQQEQKSDEETKKNAMKLIN
What is the function of this protein?
This protein is thought to be involved in the control of plasmid partition.
What are the official names of this protein?
Protein StbB.
Protein: ABC3F_HUMAN
Sequence: MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPRLDAKIFRGQVYSQPEHHAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAKLAEFLAEHPNVTLTISAARLYYYWERDYRRALCRLSQAGARVKIMDDEEFAYCWENFVYSEGQPFMPWYKFDDNYAFLHRTLKEILRNPMEAMYPHIFYFHFKNLRKAYGRNESWLCFTMEVVKHHSPVSWKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLYYFWDTDYQEGLRSLSQEGASVEIMGYKDFKYCWENFVYNDDEPFKPWKGLKYNFLFLDSKLQEILE
What is the function of this protein?
DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms.  Exhibits antiviral activity against viruse such as HIV-1 or HIV-2 (PubMed:15141007, PubMed:15152192, PubMed:23001005, PubMed:34774569).  After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA (PubMed:15141007).  The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells.  Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single- or double-stranded RNA.  Exhibits antiviral activity also against hepatitis B virus (HBV), equine infectious anemia virus (EIAV), xenotropic MuLV-related virus (XMRV) and simian foamy virus (SFV) and may inhibit the mobility of LTR and non-LTR retrotransposons.  May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.
What are the official names of this protein?
DNA dC->dU-editing enzyme APOBEC-3F, Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3F, A3F.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, P-body.
Protein: Y1419_OCEIH
Sequence: MSYQYPMDETWSTEEIIDVVNFFSLIEKAYEKQVDREEILALYRRFKQIVPSKSEEKKLFTQFQEASGYSSYHVVKKARETNESNIRM
What are the official names of this protein?
UPF0223 protein OB1419.
What is the protein family that this protein belongs to?
Belongs to the UPF0223 family.
Protein: GLYA_TERTT
Sequence: MFDKTQTIADFDPDVWQAIVDEGVRQEEHIELIASENYTSPLVMVAQGSKLTNKYAEGYPSKRYYGGCEYVDKVEELAIERAKALFGADYANVQPHSGSQANSAVYAALCAPGDTVLGMSLDHGGHLTHGAKVNFSGKMYNAVQYGLNPETGLVDYEEIAALAREHKPKMIVAGFSAYSQVLDWQKFRDIADEVGAYLMVDMAHVAGLVAAGVYPSPVQIADVTTTTTHKTLRGPRGGIILAKANPEIEKKLNSAVFPGGQGGPLMHVIAGKAISFKEAMSDEYKAYQQRVVDNAKTMAATFIKRGFKIVSGGTENHLMLVDLIGKDYSGKDADAALGAANITVNKNAVPNDPRSPFVTSGLRVGTPAITTRGFGETEVVDLTNWMCDVLESLEAGNSEAVIADVKAKVLDVCGKFPVYGSN
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCMA_PSEPG
Sequence: MTLHLQAAGLACERDWRLLFEQLDFELGAGDMLQISGPNGSGKTSLLRLLAGLMQPTAGQILLGGKPLAEQRHALASILLWIGHAAGIKDLLTAEENLTWLCALHQPASREAIWAALEAVGLRGFEDVPCHTLSAGQQRRVALARLHLACPPLWILDEPFTALDKQGVAQLEAHLAAHCEQGGTVVLTTHHTLERKPSGYRELNLGQWAA
What is the function of this protein?
Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RHIR_RHILV
Sequence: MKEESSAVSNLVFDFLSESASAKSKDDVLLLFGKISQYFGFSYFAISGIPSPIERIDSYFVLGNWSVGWFDRYRENNYVHADPIVHLSKTCDHAFVWSEALRDQKLDRQSRRVMDEAREFKLIDGFSVPLHTAAGFQSIVSFGAEKVELSTCDRSALYLMAAYAHSLLRAQIGNDASRKIQALPMITTREREIIHWCAAGKTAIEIATILGRSHRTIQNVILNIQRKLNVVNTPQMIAESFRLRIIR
What is the function of this protein?
Positive regulator of the rhiABC operon.
What are the official names of this protein?
Regulatory protein RhiR.
Protein: PUR9_STRGC
Sequence: MTKRALISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDSAGVETIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNNIELIDLVVVNLYPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELSANGETTYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQAMRYGENPQQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKYRPTVVALKHMNPCGIGQADDIKTAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSYTDEALAILTNKKKNLRILALPFDAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQVVTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRIAIDQAKDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFTGVRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: SLMA_ACTPJ
Sequence: MIQPTVKMPKKSVKERQQQVLEVLIGLLNSEDGMQRVTTERLAKAVGVSEGALYRYFPSKTKMFEALIERIEQTLTGYINASKRKENTTASTVKAILYTVIEFARKNPGVTRILTGHALMFEDDQLKARVAKFFDGLEFQFANILQMSKLREGKTFEDERALAGYLVNFCEGQFLRLVRSNFSYNQHQHFEKQWALIKPLFE
What is the function of this protein?
Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid.  Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers.  SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
What are the official names of this protein?
Nucleoid occlusion factor SlmA.
What is the protein family that this protein belongs to?
Belongs to the nucleoid occlusion factor SlmA family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: PA24A_MOUSE
Sequence: MSFIDPYQHIIVEHQYSHKFTVVVLRATKVTKGTFGDMLDTPDPYVELFISTTPDSRKRTRHFNNDINPVWNETFEFILDPNQENVLEITLMDANYVMDETLGTATFPVSSMKVGEKKEVPFIFNQVTEMILEMSLEVCSCPDLRFSMALCDQEKTFRQQRKENIKENMKKLLGPKKSEGLYSTRDVPVVAILGSGGGFRAMVGFSGVMKALYESGILDCATYIAGLSGSTWYMSTLYSHPDFPEKGPEEINEELMKNVSHNPLLLLTPQKVKRYVESLWKKKSSGQPVTFTDIFGMLIGETLIQNRMSMTLSSLKEKVNAARCPLPLFTCLHVKPDVSELMFADWVEFSPYEIGMAKYGTFMAPDLFGSKFFMGTVVKKYEENPLHFLMGVWGSAFSILFNRVLGVSGSQNKGSTMEEELENITAKHIVSNDSSDSDDEAQGPKGTENEEAEKEYQSDNQASWVHRMLMALVSDSALFNTREGRAGKVHNFMLGLNLNTSYPLSPLRDFSSQDSFDDELDAAVADPDEFERIYEPLDVKSKKIHVVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDTSPPFKELLLAEKWAKMNKLPFPKIDPYVFDREGLKECYVFKPKNPDVEKDCPTIIHFVLANINFRKYKAPGVLRETKEEKEIADFDIFDDPESPFSTFNFQYPNQAFKRLHDLMYFNTLNNIDVIKDAIVESIEYRRQNPSRCSVSLSNVEARKFFNKEFLSKPTV
What is the function of this protein?
Has primarily calcium-dependent phospholipase and lysophospholipase activities, with a major role in membrane lipid remodeling and biosynthesis of lipid mediators of the inflammatory response (PubMed:1904318, PubMed:9403692, PubMed:9403693).  Plays an important role in embryo implantation and parturition through its ability to trigger prostanoid production (PubMed:9403692, PubMed:9403693).  Preferentially hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity).  Selectively hydrolyzes sn-2 arachidonoyl group from membrane phospholipids, providing the precursor for eicosanoid biosynthesis via the cyclooxygenase pathway.  In an alternative pathway of eicosanoid biosynthesis, hydrolyzes sn-2 fatty acyl chain of eicosanoid lysophopholipids to release free bioactive eicosanoids.  Hydrolyzes the ester bond of the fatty acyl group attached at sn-1 position of phospholipids (phospholipase A1 activity) only if an ether linkage rather than an ester linkage is present at the sn-2 position.  This hydrolysis is not stereospecific.  Has calcium-independent phospholipase A2 and lysophospholipase activities in the presence of phosphoinositides.  Has O-acyltransferase activity.  Catalyzes the transfer of fatty acyl chains from phospholipids to a primary hydroxyl group of glycerol (sn-1 or sn-3), potentially contributing to monoacylglycerol synthesis (By similarity).
What are the official names of this protein?
Cytosolic phospholipase A2, cPLA2, Phospholipase A2 group IVA.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane. Nucleus envelope. Note=Translocates to intracellular membranes in a calcium-dependent way.
Protein: CBID_GEOTN
Sequence: METKKTLREGYTTGLCAAAATKAALTALITGQVQTDATIRIPIGRVVTFSLASCSFDGETATASVVKDGGDDPDATHGALIVSTVSWASSPGVHIDGGEGVGRVTKPGLPVPVGEAAINPVPRQMIHEAVNEVLAQYGLHRGVNVVISVPGGEEIAKKTLNPRLGIMGGISILGTRGIVVPFSTAAYRASIVQALQVAKANGCRHVVITTGGRSEKYAMQEYPHLPEEAFIEMGDFVGFTLKQCKRLGIKMVSMVGMMGKFSKVAQGVMMVHSKSAPVDFGFLAALAEQAGASSALVAAVRGANTAAQVGDMMQEAGCMKFFELLCEACCQAALHEVGGGLTVATSIYTMNGQQLGKAVQTDGDDEVDRCGC
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: VATC_THET8
Sequence: MADDFAYLNARVRVRRGTLLKESFFQEALDLSFADFLRLLSETVYGGELAGQGLPDVDRAVLRTQAKLVGDLPRLVTGEAREAVRLLLLRNDLHNLQALLRAKATGRPFEEVLLLPGTLREEVWRQAYEAQDPAGMAQVLAVPGHPLARALRAVLRETQDLARVEALLAKRFFEDVAKAAKGLDQPALRDYLALEVDAENLRTAFKLQGSGLAPDAFFLKGGRFVDRVRFARLMEGDYAVLDELSGTPFSGLSGVRDLKALERGLRCVLLKEAKKGVQDPLGVGLVLAYVKEREWEAVRLRLLARRAYFGLPRAQVEEEVVCP
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit C, V-ATPase subunit C.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase V0D/AC39 subunit family.
Protein: VP16_HHV2H
Sequence: MDLLVDDLFADADGVSPPPPRPAGGPKNTPAAPPLYATGRLSQAQLMPSPPMPVPPAALFNRLLDDLGFSAGPALCTMLDTWNEDLFSGFPTNADMYRECKFLSTLPSDVIDWGDAHVPERSPIDIRAHGDVAFPTLPATRDELPSYYEAMAQFFRGELRAREESYRTVLANFCSALYRYLRASVRQLHRQAHMRGRNRDLREMLRTTIADRYYRETARLARVLFLHLYLFLSREILWAAYAEQMMRPDLFDGLCCDLESWRQLACLFQPLMFINGSLTVRGVPVEARRLRELNHIREHLNLPLVRSAAAEEPGAPLTTPPVLQGNQARSSGYFMLLIRAKLDSYSSVATSEGESVMREHAYSRGRTRNNYGSTIEGLLDLPDDDDAPAEAGLVAPRMSFLSAGQRPRRLSTTAPITDVSLGDELRLDGEEVDMTPADALDDFDLEMLGDVESPSPGMTHDPVSYGALDVDDFEFEQMFTDAMGIDDFGG
What is the function of this protein?
May play a role in the aggregation of tegument proteins around nucleocapsids during virus morphogenesis.
What are the official names of this protein?
Tegument protein VP16, Alpha trans-inducing protein, Alpha-TIF, ICP25, Vmw65.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae tegument protein VP16 protein family.
What are the subcellular locations of this protein?
Virion tegument. Host nucleus.