PharMolix/UniProtQA huggingface dataset:
Protein: CYC2_BLAVI
Sequence: MRKLVFGLFVLAASVAPAAAQDAASGEQVFKQCLVCHSIGPGAKNKVGPVLNGLFGRHSGTIEGFAYSDANKNSGITWTEEVFREYIRDPKAKIPGTKMIFAGVKDEQKVSDLIAYIKQFNADGSKK
What is the function of this protein?
Cytochrome c2 is found mainly in purple, non-sulfur, photosynthetic bacteria where it functions as the electron donor to the oxidized bacteriochlorophyll in the photophosphorylation pathway.  However, it may also have a role in the respiratory chain and is found in some non-photosynthetic bacteria.
What are the official names of this protein?
Cytochrome c2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
Protein: TM209_MOUSE
Sequence: MMQGDVSPNPSLIDRTIKMRKETETRKVVLAWGLLNVSMAGMIYTEMTGKLISTYYNVTYWPLWYIELALASLFSLNALFDFWRYFKYTVAPTSLVVSPGQQALLGLKQAVVQTTPPRDLAATQISPSPPSPSIQGQSVLSYSPSRSPSTSPKFATSCMTGYSPQLQGLSSGGLGSYSPGVTYSPVSGYNKLASFSLSPSSPYPTTVGPVESSGLRARYRSPPTVYNSPTDKEDYMTDLRTLDTFLRSEEEKQHRVKLGSPDSTSPSTSPTFWNYSRSVGDYAQTLKKFQYQLACRSQAPCANKDEADLISKQAAEEVWARVTMNRQLLDHMDSWTAKFRNWISETILVPLVQEIESVSTQMRRMGCPELQIGEASVTSLKQAALVRAPLIPTLNAIVQYLDLTPNQEYLFERIKELSQGGCMSSFRWNRGGDFKGRKWDTDLPTDSAIIMHVFCTYLDSRLPPHPKYPDGKTFTSQHFVQTPNKPDVTNENVFCIYQSAVNPPHYELIYQRHVYNLPKGRNNMFHTLLMFLYIIKTKESGMLGRVNLGLSGVNILWIFGE
What are the official names of this protein?
Transmembrane protein 209.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: COAE_STRP8
Sequence: MIIGITGGIASGKSTVVKVIRKAGYQVIDADQVVHDLQEKGGRLYEALREAFGNQILKADGELDRTKLSEMLFSNPDNMATSSAIQNQIIKEELAAKRDHLAQSQAIFFMDIPLLMELGYQDWFDAIWLVYVDAQTQLQRLMARNRLDKGKARQRIASQLPIEEKKPYASLVIDNNGDMETLIKQVQSALLSLANPR
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPSD_CMVAS
Sequence: MDKSESTSAGRNRRRRPRRGSRSASSSADANFRVLSQQLSRLNKTLAAGRPTINHPTFVGSERCKPGYTFSSITLNPPKIDRGSYYGKRLLLPDSVTEFDKKLVSRIQIRVNPLPKFDSTVWVTVRKVPASSDLSVAAISAMFADGASPVLVYQYAASGVQANNKLLYDLSAMRADIGDMRKYAVLVYSKDDALETDELVLHVDVEHQRIPTSGVLPV
What is the function of this protein?
Capsid protein.  Probably binds RNA and plays a role in packaging (By similarity).
What are the official names of this protein?
Capsid protein, CP, Coat protein.
What is the protein family that this protein belongs to?
Belongs to the cucumovirus capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: YQGF_BURM9
Sequence: MSAALSRDATLLAFDYGEKRIGVAVGNLLTRTARALVIVRNLNREHRFKAVGELIAEWKPDALVVGLPLHPDGAPHEMTQRAMRFGNQLNGRFNLPVSWVDERYSSVEARAGLRARGDAADRVDAEAARVILQQYLDGLPDHHEFN
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HMUV_ECOL6
Sequence: MISAQNLVYSLQGRRLTDNVSLTFPGGEIVAILGPNGAGKSTLLRQLTGYLQPDSGECRLFNKPLNEWSITELAKHRAVMRQNSHMAFPFSVQEVIQMGRHPHRTGNQDNETAQIMALCDCQALANRDYRQLSGGEQQRVQLARLLVQLWEPTPSPKWLFLDEPTSALDIHHQQHLFRLLRQLVHERQFNVCCVLHDLNLAARYADRVVLMQKGKVIANGKPQDVLTQQALTMLYGADITVLKDPANHSPLIVLDH
What is the function of this protein?
Part of the ABC transporter complex HmuTUV involved in hemin import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Hemin import ATP-binding protein HmuV.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Heme (hemin) importer (TC 3.A.1.14.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TPIS_METS5
Sequence: MKVPIILVNFKVYETSYGRRGLEMAKIVEKVALETSTEIIIAVPATMITRVAESVTIPVYAQHVDGVPEGAHTGAVTPELIKDAGAKGSLLNHSERRVRMDEMDDALKRMKKLGLESVICVDRYELVAPMALLKPTAVLVEPPELIGTGVSVSKARPEVITSAVDEIRKVQGVYLIAGAGITSGEDVYVAMKLGSDGVGAASAIMKAKEPQKVLLDFVNGAIRALEER
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BMP7_HUMAN
Sequence: MHVRSLRAAAPHSFVALWAPLFLLRSALADFSLDNEVHSSFIHRRLRSQERREMQREILSILGLPHRPRPHLQGKHNSAPMFMLDLYNAMAVEEGGGPGGQGFSYPYKAVFSTQGPPLASLQDSHFLTDADMVMSFVNLVEHDKEFFHPRYHHREFRFDLSKIPEGEAVTAAEFRIYKDYIRERFDNETFRISVYQVLQEHLGRESDLFLLDSRTLWASEEGWLVFDITATSNHWVVNPRHNLGLQLSVETLDGQSINPKLAGLIGRHGPQNKQPFMVAFFKATEVHFRSIRSTGSKQRSQNRSKTPKNQEALRMANVAENSSSDQRQACKKHELYVSFRDLGWQDWIIAPEGYAAYYCEGECAFPLNSYMNATNHAIVQTLVHFINPETVPKPCCAPTQLNAISVLYFDDSSNVILKKYRNMVVRACGCH
What is the function of this protein?
Growth factor of the TGF-beta superfamily that plays important role in various biological processes, including embryogenesis, hematopoiesis, neurogenesis and skeletal morphogenesis (PubMed:31208997).  Initiates the canonical BMP signaling cascade by associating with type I receptor ACVR1 and type II receptor ACVR2A (PubMed:9748228, PubMed:12667445).  Once all three components are bound together in a complex at the cell surface, ACVR2A phosphorylates and activates ACVR1.  In turn, ACVR1 propagates signal by phosphorylating SMAD1/5/8 that travel to the nucleus and act as activators and repressors of transcription of target genes (PubMed:12478285).  For specific functions such as growth cone collapse in developing spinal neurons and chemotaxis of monocytes, uses also BMPR2 as type II receptor (PubMed:31208997).  Can also signal through non-canonical pathways such as P38 MAP kinase signaling cascade that promotes brown adipocyte differentiation through activation of target genes, including members of the SOX family of transcription factors (PubMed:27923061).
What are the official names of this protein?
Bone morphogenetic protein 7, BMP-7, Osteogenic protein 1, OP-1.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATG13_CANAL
Sequence: MLSDFKQQQQQKHHSHNPPNSHDDTQTKLQVAKLTQVIQKFFTKAAQIILESRAYPETSTPSLYPTKEESSKINKWFNLYMTNIPDSCKDDLKLWKGVDLTTIPPMIIETYIDLRSLPADQTLVLMDDEKHPWTVAKSRGKKQEVVLERWLIEFEPNTTDATVMVEELPLSYKQAIVLFRSIYGFTRLMPAFKVKKNLQNKLPLGNKILDGNQPISSKGRIGLSKPIINTRTNESHMTQKYFQPVHTSLGTLKISVAYRMDSEFCLHENEELLSSHFHKRDEEETKKKVSSSVSPLSSGTSLKETSTSPRKSQPPIRIQPFKVGSMSTSPPVQSPSISQPGTAPIQNQPSVPSSSLERRVSITSNKSTSNASLAAFLRNARSSTPSANNIPIINANPISGTSVPRSFSSSTGHEDSIFVNPDSASNTPRFASSFGSRASRRYSSTSIRQQTPQSDLMGQTNSVDAALSGIDADDDISDFVRMIDSKSDLRLGGGGGGGNSSVHNMSINESSYHGDALNKFQSLRSQYQQLSDSVSASLILQSRHSSRKSSLNSPAGSFDSHHHQHQQQQQQQQNQQQSQSPHTNTTSSIHSHAHSYSHSRMKDARPRSEDHQQTKFSAARRSSNISPTTAVPSSIGTPSSISSRIPHVTTIISSSDVSSTGGNRTKSAATTAIVSGMATSPSIYDYRSPRYQNVFDDDDEDDNDEEEGDREGNQLHEGRNSTESSQNQSKRIMKHIKKDEEDSEDDEDLLFTMSDMNSRNF
What is the function of this protein?
Activates the ATG1 kinase in a nutritional condition dependent manner through the TOR pathway, leading to autophagy.  Also involved in cytoplasm to vacuole transport (Cvt) and more specifically in Cvt vesicle formation.  Seems to play a role in the switching machinery regulating the conversion between the Cvt pathway and autophagy.  Finally, ATG13 is also required for glycogen storage during stationary phase (By similarity).
What are the official names of this protein?
Autophagy-related protein 13.
What is the protein family that this protein belongs to?
Belongs to the ATG13 family. Fungi subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure.
Protein: YORP_BACSU
Sequence: MPKYWSYPVGLAVEINNNARYGCPHHVGRKGKIIEHLHSATYDYAVSDETGDITYFKEHELTPLKGGLAYV
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YorP.
Protein: SYA_CLAMS
Sequence: MQTADIRNAWLTYFGDRGHTVVPSASLVSDDPTLLFTVAGMVPFVPYLTGVVPAPFARATSVQKCIRTLDIEEVGRTPRHGTFFQMNGNFSFGDYFKEQAIAYAWELLTTSEADGGLGFSPDDLWVTVYHEDDEARQAWKRIAGLPDERIQGLGRDTNYWHTGQPGPAGPCSEIFFDRGPAYGADGGPATDDDRYVEIWNLVFMQYLRGAGTGKSDFEILGDLPTRNIDTGMGLERVAFIKQGVENMYETDQVRPVLDRAAELSGRRYGADHEDDVRMRIVADHVRSSVMLMSDGVRPSNEGRGYILRRLMRRTVRAMRLMGVDAATFGELFPASRDAMKAAYPEVSDDFDRISRLAYAEEETFLRTLSGGTTILDVAVGETKAKGGERIAGDTAFLLHDTFGFPIDLTLEMAEENGLTVDREAFDRLMLEQRTRAKADAKSKKTALADLTVYSEFRAAGETRFTGYDELETGTTILGLIVGGHSVDHAVAGDIAEVILPETSLYAESGGQEADAGSIVGQGFDLEVLDVQKPVKGLISHRVQVRSGEVGVGDAATTIVDADWRRGATQAHSGTHLVHAALRQVLGQDAHQSGSYNRAGYMRLDFAWNQALSPATRSEIEDIANGAVRDDLQVVTRVMPIDEAKQLGAMALFGEKYGDTVRVVDIGGPWSRELCAGTHVSSSAQIGLINVVGESSVGSTNRRIESLVGREAFQDLAVERAIVSQLTSSLKTPREQLPDRIADLLQNLKTAERRIADFEAQALQQRVPTLLAQGSRVGSVTLIQESLGSVRSADEVRQLVTLVRERAGSDPVVVALAGDAGGKPTVIVATNQAARDAGAKAGQLARAAAAVLGGGGGGKDDLAQGGGSDVSAIGEALAAVRQALDS
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERF26_ARATH
Sequence: MADPNNPITEPKAIIQSSTSSSVTIVPVPTCGDSLSDSATCENPCPLDTITTTTTTVCFAAPSSTASGNDINTLMATDTDISRRKKNPVYRGIRCRSGKWVSEIREPKKTTRVWLGTYPTPEMAAAAYDVAALALKGGDTLLNFPDSLGSYPIPLSSSAAHIRCAAAAAAATRGAAGAAVKVGQKKEDKVYDTAESSTMGFVDEEELLNMPGLLADMAKGMMVAPPWMGSPPSDDSPENSDGESLWSY
What is the function of this protein?
Probably acts as a transcriptional activator.  Binds to the GCC-box pathogenesis-related promoter element.  May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
What are the official names of this protein?
Ethylene-responsive transcription factor ERF026.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL23_LACDB
Sequence: MDARDIILRPVITEKSADLMDSKKYTFDVALTATKLQVRDAIEEIFDVKVKSVNIMNVRGKEKRVGRYTGKIARRRKAIVALTEDSNDIKIFKDENNE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: GEMA_BPMU
Sequence: MSRTSLIKLIHVARRELQLDDDTYRAFLMQKTGKISCRELTVTQLEQVLGAMKERGFKKQNKYPRRRFKGHVTPREKVYKIWQQMAEDGFITDGGDVALDKYVQRLTAKRNGGQGVSTLAWCHGDTLLTVLETLKQWHIRCIREAFSRHGLPLPVSPSGRELRGYDAMTAAYAHARKTRRMAQ
What is the function of this protein?
Early protein responsible for decreasing host DNA gyrase activity.  Promotes DNA relaxation of bacterial host genome.  Modulates the expression of various host genes probably controlled by supercoiling of their promoters.  Host genes affected include DNA replication and cell division determinants.
What are the official names of this protein?
GemA protein, Gene product 16, gp16.
What is the protein family that this protein belongs to?
Belongs to the mulikevirus gemA protein family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: FLVC1_HUMAN
Sequence: MARPDDEEGAAVAPGHPLAKGYLPLPRGAPVGKESVELQNGPKAGTFPVNGAPRDSLAAASGVLGGPQTPLAPEEETQARLLPAGAGAETPGAESSPLPLTALSPRRFVVLLIFSLYSLVNAFQWIQYSIISNVFEGFYGVTLLHIDWLSMVYMLAYVPLIFPATWLLDTRGLRLTALLGSGLNCLGAWIKCGSVQQHLFWVTMLGQCLCSVAQVFILGLPSRIASVWFGPKEVSTACATAVLGNQLGTAVGFLLPPVLVPNTQNDTNLLACNISTMFYGTSAVATLLFILTAIAFKEKPRYPPSQAQAALQDSPPEEYSYKKSIRNLFKNIPFVLLLITYGIMTGAFYSVSTLLNQMILTYYEGEEVNAGRIGLTLVVAGMVGSILCGLWLDYTKTYKQTTLIVYILSFIGMVIFTFTLDLRYIIIVFVTGGVLGFFMTGYLPLGFEFAVEITYPESEGTSSGLLNASAQIFGILFTLAQGKLTSDYGPKAGNIFLCVWMFIGIILTALIKSDLRRHNINIGITNVDVKAIPADSPTDQEPKTVMLSKQSESAI
What is the function of this protein?
Heme transporter that promotes heme efflux from the mitochondrion to the cytoplasm.  Essential for erythroid differentiation.
What are the official names of this protein?
Feline leukemia virus subgroup C receptor-related protein 1, Feline leukemia virus subgroup C receptor, hFLVCR.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Feline leukemia virus subgroup C receptor (TC 2.A.1.28.1) family.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Multi- pass membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Mitochondrion membrane; Multi-pass membrane protein.
Protein: CATW_HUMAN
Sequence: MALTAHPSCLLALLVAGLAQGIRGPLRAQDLGPQPLELKEAFKLFQIQFNRSYLSPEEHAHRLDIFAHNLAQAQRLQEEDLGTAEFGVTPFSDLTEEEFGQLYGYRRAAGGVPSMGREIRSEEPEESVPFSCDWRKVASAISPIKDQKNCNCCWAMAAAGNIETLWRISFWDFVDVSVQELLDCGRCGDGCHGGFVWDAFITVLNNSGLASEKDYPFQGKVRAHRCHPKKYQKVAWIQDFIMLQNNEHRIAQYLATYGPITVTINMKPLQLYRKGVIKATPTTCDPQLVDHSVLLVGFGSVKSEEGIWAETVSSQSQPQPPHPTPYWILKNSWGAQWGEKGYFRLHRGSNTCGITKFPLTARVQKPDMKPRVSCPP
What is the function of this protein?
(Microbial infection) Plays a role during influenza virus infection in lungs cells ex vivo.  Acts at the level of virus entering host cytoplasm from late endosome.
What are the official names of this protein?
Cathepsin W, Lymphopain.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: DOPDA_XENLA
Sequence: MPFVELETNLPSQNVPQDLAEKLCSATATILGKPRERVNVTVRTGVSMVVGGSSAPCTQLFISSIGVVGTAEQNKEHSAKFFNFLTEQLGLAQDRILLRFVPIEPWQIGKNGTIMTFL
What is the function of this protein?
Tautomerization of D-dopachrome with decarboxylation to give 5,6-dihydroxyindole (DHI).
What are the official names of this protein?
D-dopachrome decarboxylase-A, D-dopachrome tautomerase-A.
What is the protein family that this protein belongs to?
Belongs to the MIF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATCAY_RAT
Sequence: MGTTEATLRMENVDVRDEWQDEDLPRPLPEDTGEDHLGGTVEDSSSPPSTLNLSGAHRKRKTLVAPEINISLDQSEGSLLSDDFLDTPDDLDINVDDIETPDETDSLEFLGNGNELEWEDDTPVATAKNMPGDSADLFGDGSGEDGSAANGRLWRTVIIGEQEHRIDLHMIRPYMKVVTHGGYYGEGLNAIIVFAACFLPDSSSPDYHYIMENLFLYVISSLELLVAEDYMIVYLNGATPRRRMPGIGWLKKCYHMIDRRLRKNLKSLIIVHPSWFIRTVLAISRPFISVKFISKIQYVHSLEELEQLIPMEHVQLPACVLQYEEQRLRAKRESARPPQPEFLLPRSEEKPETVEEEDRAAEVTEDQETSMS
What is the function of this protein?
Functions in the development of neural tissues, particularly the postnatal maturation of the cerebellar cortex.  May play a role in neurotransmission through regulation of glutaminase/GLS, an enzyme responsible for the production in neurons of the glutamate neurotransmitter.  Alternatively, may regulate the localization of mitochondria within axons and dendrites.
What are the official names of this protein?
Caytaxin.
What are the subcellular locations of this protein?
Cell projection, axon. Cell projection, dendrite. Presynapse. Mitochondrion. Cell projection, growth cone. Cytoplasm.
Protein: TRPA_THEKO
Sequence: MFEKGSLIPYLTAGDPSVEKTLEFLLAVEEFAGLIELGIPFSDPMADGKTIQESHYRALRNGFKLDDTFRILREFRRHSSTPVILMTYYNPVFRTGVKKFLGEAKASGADGILVVDLPVSHAGEFLDAAKEEGLKTVFLAAPNTPDERLREIDKASTGFVYLISLYGTTGARDRLPETAFEFVRRARKICNNKLAVGFGVSRREQVEELLKAGADGVVVGSALIELISRSENPVEELRRKVAELSGYSRAL
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: DTD_STAAM
Sequence: MKVVVQRVKEASVTNDTLNNQIKKGYCLLVGIGQNSTEQDADVIAKKIANARLFEDDNNKLNFNIQQMNGEILSVSQFTLYADVKKGNRPGFSNSKNPDQAVKIYEYFNDALRAYGLTVKTGEFGTHMNVSINNDGPVTIIYESQDGKIQ
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_SYNY3
Sequence: MVDCIVKNWQGEEVGNASLTLRVAKEENAAHIVHRALVRQQNNARQGNASAKTRAEVRGGGRKPWKQKGTGRARAGSIRSPLWRGGGVIFGPKPRDYSQKMNRKERRLALRTAIASRADNMVVVEAFGDQFSQPKTKELATALTRWGAKPEKRVLLILDEIPENVFLSGRNIPYLKILRADNLNIYDVLVADTIVATATALEKIQEVYGE
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: HAT1_ARATH
Sequence: MMMGKEDLGLSLSLGFAQNHPLQLNLKPTSSPMSNLQMFPWNQTLVSSSDQQKQQFLRKIDVNSLPTTVDLEEETGVSSPNSTISSTVSGKRRSTEREGTSGGGCGDDLDITLDRSSSRGTSDEEEDYGGETCRKKLRLSKDQSAVLEDTFKEHNTLNPKQKLALAKKLGLTARQVEVWFQNRRARTKLKQTEVDCEYLKRCVEKLTEENRRLEKEAAELRALKLSPRLYGQMSPPTTLLMCPSCERVAGPSSSNHNQRSVSLSPWLQMAHGSTFDVMRPRS
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
Homeobox-leucine zipper protein HAT1, Homeodomain-leucine zipper protein HAT1, HD-ZIP protein 1.
What is the protein family that this protein belongs to?
Belongs to the HD-ZIP homeobox family. Class II subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS18_STRZT
Sequence: MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKILPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: HEMA_I78AE
Sequence: MKKILLFTVIFLYAKADEICIGYLSNNSTDKVDTIIESNVTVTSSVELVETEHTGSFCSINGKQPISLGDCSFAGWILGNPMCDDLIGKTSWSYIVENQS
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: GENL2_ARATH
Sequence: MGVKYLWDVLEPCKKTFPLDHLQNKRVCVDLSCWMVELHKVNKSYCATKEKVYLRGFFHRLRALIALNCSIILVSDGAIPGIKVPTYKRRLKARFEIADDGVEPSKETSLKRNMGSEFSCIIKEAKVIASTLGILCLDGIEEAEAQCALLNSESLCDACFSFDSDIFLFGAKTVYREICLGEGGYVVCYEMDDIKKKLGLGRNSLIALALLLGSDYSQGVRGLRQEKACELVRSIGDNVILEKVASEGLSFAEKPRKSKKQVRPSVCSKKGTLPLVVINGNNRDPERLEEIKQVIDAFMNPKCHQADSNTVSRALAEFSFQRTKLQEICHQFFEWPPEKTDEYILPKVAERNLRRFANLQSRSTEVEVNLPLHKPQMPEKCPVSEIIKTRKVQGRECFEVSWNDLEGLESSIVPADLVERACPEKIIEFKEKMAAKKKKPKPKQKQKETSSPTKSSSLVELSLELQHLDLNSTSLVSRSTLEEAEQENEQQNSKKHDYLRLIDSPDRENCNNAWSNRDRLGVGMSSFPLYPETEVIDLISPCPEARSRSVSRSYQEQKSHDHQLETVIELSDSETDDEEHCKKARELRIFLQNIRKDIIL
What is the function of this protein?
Endonuclease which cleaves flap structures at the junction between single-stranded DNA and double-stranded DNA with a specific cleavage site in the 5' overhang strand exactly one nucleotide 3' of the branch point (PubMed:25037209).  Structure- and sequence-specific nuclease that resolves holliday junctions (HJs) by symmetrically oriented incisions in two opposing strands near the junction point, thus leading to ligatable products; HJs are physical links between homologous DNA molecules that arise as central intermediary structures during homologous recombination and repair in meiotic and somatic cells (PubMed:25037209).  Structure-specific nuclease with 5'-flap endonuclease activity, preferentially cleaving static flaps 5' overhang strand exactly one nucleotide in the 3' direction of the branch point and, to lower extent, on the two neighboring positions (PubMed:25037209).  Also able to cleave double-stranded flap strand 1 one nucleotide in the 3' direction of the branch point (PubMed:25037209).  Together with MUS81, essential for the resolution of toxic replication structures to ensure genome stability, and to maintain telomere integrity and replication (PubMed:26704385).
What are the official names of this protein?
Single-strand DNA endonuclease 1, AtSEND1, Flap endonuclease GEN-like 2, XPG-like endonuclease 2.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. GEN subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: MLTC_ACTP7
Sequence: MKKYTKYLPLLLIIPFLAACGSSSPKKSKRTKTRVDYNTKDTNGLDILTGQFSHNIDDIWGSNELLVASKKDYVKYTDKFYTRSHISFEDGQITIETLGDQNHLRNSIIHTLLMGSDPKGIDLFASGDAPISSNPFLAGQVNDQFGRDINNIAIANDFATYLIQNKLQTRRLQNGRTVTYVAIKMVAGHIEVRARQYLPLVRKMAKRYGIEPSLILGIMEVESAFNPYAVSYANAIGLMQVVPRTAGRDIFARKGFDGQPDRAYLYNPSQNIDSGTLYLAILRDEYLEGITNPTAKRYAMISAYNSGAGAVLKVFDYDKYDAIDRINELSPDAVYRILTTAHPSSQARNYLKKVSKAREKYLHIR
What is the function of this protein?
Murein-degrading enzyme.  May play a role in recycling of muropeptides during cell elongation and/or cell division.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase C, Murein lyase C.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: RL3_PSEAE
Sequence: MTIGVVGRKCGMTRIFTEEGVSIPVTVIEVEPNRVTQFKTEETDGYRAVQVTAGERRASRVTKAQAGHFAKANVAAGRGVWEFRLGEEQYAAGDQITVDLFQAGQMVDVTGESKGKGFAGTIKRWNFRGQDNTHGNSVSHRVPGSIGQCQTPGRVFKGKKMSGHLGAERVTVQSLEIVRVDAERNLLLVKGAVPGATGGDVIVRPAAKARG
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.