PharMolix/UniProtQA huggingface dataset:
Protein: NU6C_ANTAG
Sequence: MNIINLPELNYEVFFVFIELGLIFGSLGVVFLTNIVYSAFLLGLVFVCISFLYLLLDADFVATAQILIYVGAVNILIVFAVMLINKPQSLQFLPSWTVGDTITLILCTSLFFLLISMILSISWSNIFSIAQSNKIGEQVLKSSVQGIGSSLLIDFLLPFELLSIVLLVALIGAITIARREKKVKLQKNRTLQVTKDSFIL
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 6, chloroplastic, NAD(P)H dehydrogenase subunit 6, NADH-plastoquinone oxidoreductase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: TERT_YEAST
Sequence: MKILFEFIQDKLDIDLQTNSTYKENLKCGHFNGLDEILTTCFALPNSRKIALPCLPGDLSHKAVIDHCIIYLLTGELYNNVLTFGYKIARNEDVNNSLFCHSANVNVTLLKGAAWKMFHSLVGTYAFVDLLINYTVIQFNGQFFTQIVGNRCNEPHLPPKWAQRSSSSSATAAQIKQLTEPVTNKQFLHKLNINSSSFFPYSKILPSSSSIKKLTDLREAIFPTNLVKIPQRLKVRINLTLQKLLKRHKRLNYVSILNSICPPLEGTVLDLSHLSRQSPKERVLKFIIVILQKLLPQEMFGSKKNKGKIIKNLNLLLSLPLNGYLPFDSLLKKLRLKDFRWLFISDIWFTKHNFENLNQLAICFISWLFRQLIPKIIQTFFYCTEISSTVTIVYFRHDTWNKLITPFIVEYFKTYLVENNVCRNHNSYTLSNFNHSKMRIIPKKSNNEFRIIAIPCRGADEEEFTIYKENHKNAIQPTQKILEYLRNKRPTSFTKIYSPTQIADRIKEFKQRLLKKFNNVLPELYFMKFDVKSCYDSIPRMECMRILKDALKNENGFFVRSQYFFNTNTGVLKLFNVVNASRVPKPYELYIDNVRTVHLSNQDVINVVEMEIFKTALWVEDKCYIREDGLFQGSSLSAPIVDLVYDDLLEFYSEFKASPSQDTLILKLADDFLIISTDQQQVINIKKLAMGGFQKYNAKANRDKILAVSSQSDDDTVIQFCAMHIFVKELEVWKHSSTMNNFHIRSKSSKGIFRSLIALFNTRISYKTIDTNLNSTNTVLMQIDHVVKNISECYKSAFKDLSINVTQNMQFHSFLQRIIEMTVSGCPITKCDPLIEYEVRFTILNGFLESLSSNTSKFKDNIILLRKEIQHLQAYIYIYIHIVN
What is the function of this protein?
Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes.  It elongates telomeres.  It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
What are the official names of this protein?
Telomerase reverse transcriptase, Telomerase catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the reverse transcriptase family. Telomerase subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: BIOF_BACAH
Sequence: MNQPWRTHLQTKLQQLHEQGQYRNLHVTEQAEETWLIRDEKRMLNLASNNYLGLAGDERLKEAAIVCTRKYGTGATASRLVVGNYSLYEEVERSICNWKGTEKALVVNSGFTANVGAISSLACRHDIVFSDKLNHASIVDGIILSGAEHKRYRHNDLNHLEVLLKTASPEKRKLIVTDTVFSMDGDTAYLRELVQLKEKYGAIIIVDEAHASGIYGIGGAGLSHIEKDLAQKIDIHMGTFSKALGCYGAYLTGDAIYIEYLQNMMRSFIFTTALPPSTLGAVQKAIEIVQEDHKRRENLIANGEYFRSKLREAGFNIGNSSTHIVPIVVGSNENTLRFSKRLQEAGIAAIAIRPPTVPVHSSRIRFAVTSQHTIADLKWAIDRITHIAKEEELFV
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
Putative 8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: AMZA_SULIK
Sequence: MTEMKILIVTLTYIEKSIIDEIVNNLSSYGLEVDILFDSRKYLPISAFNWERLQYDAEKVLSFLKSKYDFNYDSIIFLADSDGYIDGYNFVFGLTIDNFAIIFLNRLREEFYNRKPDLELFMKRVVKEVTHEAGHTLGLGHCNTIGCVMNFSNTVEDVDKKQARFCKNCIYKIENLSKYLQRK
What is the function of this protein?
Probable zinc metalloprotease whose natural substrate is unknown.
What are the official names of this protein?
Archaemetzincin.
What is the protein family that this protein belongs to?
Belongs to the peptidase M54 family.
Protein: FLID_BORBU
Sequence: MASGFFVPGLESKYNTKEIRESMLKSDKAKIDSSFKKLESLEQEKSAWQLINRKISTLNSLAKELTSLNSPFNLMSGNSSNSEVLTLSTRYGSKNETHKLIVDQIASADVFLSSNFDPKKVTIPEGDYIFLVGKKEINVKSNGNIDLLVKDINNKGKGFLSAKIVKSDKNGNSRFVLQSLKEGKENKLVIKGEGLSFAKQIGILSELKTNFNPNLSDIVVNQSSSNNKLAFENNGLVLNPLSEVSIEIPEDIEITSRSKIKFEVKYFDTGLEEPDSKIIFNPGGATFKDAKVESEDSVVDLGSDLKTPLEKKYIQMNMVKICSKEGSLELPLINISNNFEEVEVDVGALSNLEEINIENKANNKVIVISNVEIFDPKNRDGHLPINAKSFAENAKIKFDGVDVERDSNVINDLVPNVTLSLKKPSSDMVEAKIEPDYEGIKRVLLDFIGAYNEVLAEINIVSSNEDQPNNQKSNIVEELTYLSDSQKEEAYKNLGILRSEFLLKNLKSKLESIIFKPYVTSDPNFSIINQMGVFTNSISSSGGLSRYLRLDEKKFDESIRNNIDNVRELFLYDLNGDRVYDNGIAKMLGDCLSPLVASGGVIYNKIKNYDLKIFNQKNKVEDYKKKYEDRERKVEGELNTLDFTVKRMKDQENTLKAFDFNQRNK
What is the function of this protein?
Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament.  Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end (By similarity).
What are the official names of this protein?
Flagellar hook-associated protein 2, HAP2, Filament cap protein, Flagellar cap protein.
What is the protein family that this protein belongs to?
Belongs to the FliD family.
What are the subcellular locations of this protein?
Periplasmic flagellum. Periplasm.
Protein: GID4_YEAST
Sequence: MINNPKVDSVAEKPKAVTSKQSEQAASPEPTPAPPVSRNQYPITFNLTSTAPFHLHDRHRYLQEQDLYKCASRDSLSSLQQLAHTPNGSTRKKYIVEDQSPYSSENPVIVTSSYNHTVCTNYLRPRMQFTGYQISGYKRYQVTVNLKTVDLPKKDCTSLSPHLSGFLSIRGLTNQHPEISTYFEAYAVNHKELGFLSSSWKDEPVLNEFKATDQTDLEHWINFPSFRQLFLMSQKNGLNSTDDNGTTNAAKKLPPQQLPTTPSADAGNISRIFSQEKQFDNYLNERFIFMKWKEKFLVPDALLMEGVDGASYDGFYYIVHDQVTGNIQGFYYHQDAEKFQQLELVPSLKNKVESSDCSFEFA
What is the function of this protein?
Substrate-recognition component of the GID complex, a multisubunit ubiquitin ligase that targets enzymes involved in gluconeogenesis for proteasomal degradation when cells are shifted to glucose-containing medium (PubMed:12686616, PubMed:18508925, PubMed:28126757).  Specific for substrates with an N-terminal Pro (Pro/N-degron), including FBP1, ICL1 and MDH2 (PubMed:28126757).  Has high affinity for the N-terminal sequence Pro-Thr-Leu-Val, and can bind peptides with an N-terminal sequence of the type Pro-[Gly,Ala,Ser,Thr,Asp,Asn,Tyr,His]-[Ala,Val,Leu,Ile,Lys,Arg]-[Val,Cys,Pro,Leu,Ile,Trp] (PubMed:28126757).  Required for vacuolar degradation of FBP1 when cells are shifted to glucose-containing medium, probably by targeting FBP1-containing vesicles to the vacuole, but is not required for FBP1 sequestration in cytoplasmic vesicles (PubMed:9508768).
What are the official names of this protein?
Vacuolar import and degradation protein 24, Glucose-induced degradation protein 4.
What is the protein family that this protein belongs to?
To yeast YGR066c and S.pombe SpAC3H1.14.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Peripheral membrane protein. Note=Colocalizes with FBPase-containing vesicles.
Protein: RBFA_STAHJ
Sequence: MNNMRAERVGEQMKKEIMDIVNNKVKDPRVGFITITDVDLTNDLSQAKVYLTVLGSEKEVNDTFKALDKAKGFIKSELGSRMRLRIVPELFFEYDESIEYGNKIEKMIQDLHKQDR
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_PSEPG
Sequence: MSKRDYYEVLGVERGASEADLKKAYRRLAMKYHPDRNPGDKESEDKFKEANEAYEVLSDASKRAAFDQYGHAGVDPSMGGGGAGFGGANFSDIFGDVFSDFFGGGRGGGRGGAQRGSDLRYTLELNLEEAVRGTTVSIRVPTLVNCQPCDGSGAKKGSTPSTCPTCGGIGQVRMQQGFFSVQQTCPRCHGQGKIITDPCTSCHGEGRVEEYKTLSVKVPAGVDTGDRIRLSGEGEAGTHGGPTGDLYVVISVREHEIFQRDGKHLYCEVPISYTDAALGGELEVPTLDGRVKLKIPEGTQTGKQFRLRGKGVAPVRGGGAGDLLCRVAVETPVNLSRRQRELLEELRDSLEGDSSHSPKASGWFDGVKRFFGDL
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: USP10_PINMG
Sequence: MKCLVVLTALFGISTASFLGCNLSPVWGVKNAYRSGLQTYWCPPGLKFDPFGCCCDFPFDDLVEDLAGLLGGAGNGGNGGGGNGGNGGGGNGGNNGNGNGNNGLKKYETCYDC
What are the official names of this protein?
Uncharacterized shell protein 10, Nacre uncharacterized shell protein 17.
What are the subcellular locations of this protein?
Secreted.
Protein: CYAY_ECO24
Sequence: MNDSEFHRLADQLWLTIEERLDDWDGDSDIDCEINGGVLTITFENGSKIIINRQEPLHQVWLATKQGGYHFDLKGDEWICDRSGETFWDLLEQAATQQAGETVSFR
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: YJJB_SALPB
Sequence: MGIIDFLLALMQDMILSAIPAVGFAMVFNVPHRALPWCALLGALGHGSRMLMMSAGFNIEWSTFMASLLVGSIGIQWSRWYLAHPKVFTVAAVIPMFPGISAYTAMISAVKISHLGYSEPMMITLLTNFLKASSIVGALSIGLSVPGLWLYRKRPRV
What is the function of this protein?
Involved in succinate export with YjjP.  Both proteins are required for export.
What are the official names of this protein?
Probable succinate transporter subunit YjjB.
What is the protein family that this protein belongs to?
Belongs to the ThrE exporter (TC 2.A.79) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TATB_HYDCU
Sequence: MFDIGFLEIIVIMVIALIVIGPERMPEVARKIGQFMGKTKRFINSMKENSEITETVRDLQNSMNLEEEKRNLESVSDTLHDDFSKIQDEFGIDQEISRPFDADEPTAFSGTQFNKAPTQPKMPTTEESPSSTPETSTKETEKTSTSDVSAPSESTPESSNKS
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: GLMM_CLAMS
Sequence: MPRLFGTDGVRGLANGETITADLALRLAQAAAHVLGQDARDAGRRPVAVVARDPRVSGEFIAAAVAAGLASSGVDVFDAGVIPTPATAYLIADFDADFGVMISASHNPAPDNGIKFFAAGGRKLADELEDRIEAQLSQPVLLPTGADVGRIRRFADAEDRYVLHLLGTLQHRLDGIHVVLDCAHGAAAGISPEVSTDAGARVTVIGNDPDGMNINDRVGSTHLDLLAEAVLGHGADVGIAYDGDADRCLAVDHTGAIIDGDQIMAVLALSMARRGLLVERTLVATVMSNLGLRIAMAENDITVLQTRVGDRYVLEAMNEGGYSLGGEQSGHLVIAEHATTGDGILTGIQLLGEMAATGRSLHELASVMTVYPQVMINVRGVDRERVSDDAELNAAVARAEAELGDTGRILMRASGTEPMIRVMVEAADQATAERHAQELAALVTERLAI
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: ATPB_PTEES
Sequence: IVTKTSFLSFEISELVKKNVGYITQIIGPVLDVASSPGKMPNIYNSLIIKGQNSAGQELNVTCEVQQLLGNNEVRAVAMSATDGLTRGMGAVDTGAPLSVPVGETTLGRISNVLGEPVDNLGPVQSSTTFPIHRSAPAFIQLDTKLSIFETGIKVVDLSAPYRRGGKIGLFGGAGVGKTVLITELINNIAKAHGGVSVSGGVGERTREGNDPYMEMKESKVINEQNISESKVALVYGQMNEPPGASMRVGSTASTMAEYFRDVNKQDVLPFIDYILRFVQAGSEVSALLGRMPSAVGYQPTLGTEMGSSQERITSTKDGSITSIQAVYVPADDLTDPAPATTSAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMSQPWIVGEEHYETAQGVKQTSQRYKELQDIIAILGLDELSEEDRLTVARARKIERFSSQPSFVAEVFTGSPGKYVSLPETIKGFQMILPGELDNLPEQA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: PHLP_DROME
Sequence: MATLEDKLLGEKLEYYCSSSEGEDNGDEGGDNKGASGKSRCSGLTIDTNPDATPAGGFRQQSSTNTGPKGVVKDWQRFKQLEAERRDETERQRLALAKKLTITATTSAEDEERKRQEELDAELDELMSEDFLQQYQKQRMAEMLRQTGHHQQFGQVQQLTSHEEFLACVEQENKHTTIIIHIYERQLAACATLNKCLDSLASDYPSIKFAKICSSVAGMSRDFRTKGLPALLVYKAQAVIGNFVRLTDDLSDDFFASDVESFLIEHGIIVDRALYN
What is the function of this protein?
Functions as a co-chaperone for CCT in the assembly of heterotrimeric G protein complexes, facilitates the assembly of both Gbeta-Ggamma and RGS-Gbeta5 heterodimers.
What are the official names of this protein?
Phosducin-like protein, PHLP.
What is the protein family that this protein belongs to?
Belongs to the phosducin family.
Protein: SYE_TROWT
Sequence: MRDPRVRVRFCPSPTGAPHLGLVRTALFNWVFARKHGGGFIFRIEDTDATRNREESCSQLIDTLKWLGLDWDEGPDKGGQFGPYYQSQRGDIYQEVLDKLLAADLAYESFSTKEEIEKRNLEAGRPIQLGYDNYDRTLSEQTKAAMREAGRTPIIRLRMDDENIAFEDLVKGEVVFTDPIPDFALTRASGEPLYTLVNPVDDAFMKITHVLRGEDLLSSTPRQIALYKALITIGITDYVPFFGHLPIVMGEGNRKLSKRNPESDFYFYKARGFIREGLLNYLSLLGWSISNSRDTFSLSEMIHAFDVRDVRGNPARFDYKKCLAINAYHLRELNVEDFFLRLVPFVEEMLGIPLSFEQKNSLRAICPFVQGRVQLLTEAAEMVRFLLVDNISVDFAVTDKEIDVLRHCLALLNLLDTWESAQIASCIKQAIEQFDLQPKRIFSILRLAITGRRVSPPLFESMQILGRSASLNRVETFVTN
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHYS_ARATH
Sequence: MEDDRVFSSVHSTVFKESESLEGKCDKIEGYDFNQGVDYPKLMRSMLTTGFQASNLGEAIDVVNQMLDWRLADETTVAEDCSEEEKNPSFRESVKCKIFLGFTSNLVSSGVRDTIRYLVQHHMVDVIVTTTGGVEEDLIKCLAPTFKGDFSLPGAYLRSKGLNRIGNLLVPNDNYCKFEDWIIPIFDEMLKEQKEENVLWTPSKLLARLGKEINNESSYLYWAYKMNIPVFCPGLTDGSLGDMLYFHSFRTSGLIIDVVQDIRAMNGEAVHANPKKTGMIILGGGLPKHHICNANMMRNGADYAVFINTGQEFDGSDSGARPDEAVSWGKIRGSAKTVKVYCDATIAFPLLVAETFATKRDQTCESKT
What is the function of this protein?
Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.  Also able to produce homospermidine from putrescine (By similarity).
What are the official names of this protein?
Deoxyhypusine synthase.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine synthase family.
Protein: METE_BURMA
Sequence: MTTAHILGFPRIGAQRELKFALERYWRDGASADAERALVDTGRALRAEHWRIERDAGLDCVTVGDFAWYDHVLTTLAHVGGLPRRFGFDARALTLADYFAAARGNAAQPAMEMTKWFDTNYHYLVPEYSPATTFGPGVEWLFDEVREARALGYRAKAALVGPLTLLWLGKARDGLVERLALLPRLVPAYRALLARLREAGVDWVQIDEPIFSLDLPDAWRDAARPTYEALAPGAPKLLVATYFDDASEHAALLKALPVAGLHVDLVRADAQLDAFVADYPADKVLSCGIVDGRNVWRNDLDRSLARLAPVRDALGERLWVATSCSLLHVPVDLAHEPRLDEELKTWLAFAAQKTREVAALRDALVKGRAAVAAEFDDAAVVAAARRTSARIHNPLVKRRVAALTDADARRASAYSVRAAAQRARFGLPLLPTTTIGSFPQTPEIRRARAAFKQGVLDHLGYLEAMREQVRIAIDKQLAYGLDVLVHGEAERNDMVEYFGELLWGFAITSNGWVQSYGSRCVKPPLVYGDVYLPEPMTVGWASYAQSLSAKPVKGMLTGPVTMLQWSFVRDDQPRATTALQIALALRQETLDLEKAGIGMIQIDEPALREGLPLKARERAAYLDWAVRAFGIAASGVADDTQIHTHMCYSEFGDILPSIAALDADVISIETTRSNMELLDAFETFDYPNEIGPGVYDIHSPRVPDADEIERLILLALERIPAQRLWVNPDCGLKTREWRQVDAALAAMVDAAKRVRQKVEEAAPA
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: MREB_BACSU
Sequence: MFGIGARDLGIDLGTANTLVFVKGKGIVVREPSVVALQTDTKSIVAVGNDAKNMIGRTPGNVVALRPMKDGVIADYETTATMMKYYINQAIKNKGMFARKPYVMVCVPSGITAVEERAVIDATRQAGARDAYPIEEPFAAAIGANLPVWEPTGSMVVDIGGGTTEVAIISLGGIVTSQSIRVAGDEMDDAIINYIRKTYNLMIGDRTAEAIKMEIGSAEAPEESDNMEIRGRDLLTGLPKTIEITGKEISNALRDTVSTIVEAVKSTLEKTPPELAADIMDRGIVLTGGGALLRNLDKVISEETKMPVLIAEDPLDCVAIGTGKALEHIHLFKGKTR
What is the function of this protein?
Forms membrane-associated dynamic filaments that are essential for cell shape determination (PubMed:11290328, PubMed:15745453, PubMed:17064365, PubMed:19117023, PubMed:19659933).  Acts by regulating cell wall synthesis and cell elongation, and thus cell shape (PubMed:19659933).  A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature (By similarity).  Filaments rotate around the cell circumference in concert with the cell wall synthesis enzymes.  The process is driven by the cell wall synthesis machinery and does not depend on MreB polymerization (PubMed:21636745, PubMed:21636744).  The active movement of the MreB cytoskeleton stimulates diffusion of membrane proteins (PubMed:24603761).  Organizes peptidoglycan synthesis in the lateral cell wall (PubMed:19659933).  Also required for proper chromosome segregation (PubMed:14588250, PubMed:15745453, PubMed:17064365).  Membrane fluidity influences MreB movement; in rich medium MreB movement is significantly decreased in a floA-floT mutant (PubMed:32662773).
What are the official names of this protein?
Cell shape-determining protein MreB, Actin-like MreB protein, Rod shape-determining protein MreB.
What is the protein family that this protein belongs to?
Belongs to the FtsA/MreB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Membrane-associated (PubMed:15745453, PubMed:17064365). Localizes in the form of helical filaments that encircle the cell (PubMed:11290328, PubMed:15745453). Localization is affected by Mbl, MreBH, MreC and MreD (PubMed:15745453). Colocalizes with MreBH and Mbl (PubMed:16950129, PubMed:17064365).
Protein: AROQ_CLOB1
Sequence: MNNILVINGPNLNLLGKREPDIYGNITLENINQKIKLHFKNEDLKIDFFQSNEEGKIIDKIIESEKKYNAIVINPAAYSHYSIAILDAMRSINIPVVEVHLSNIYKREEYRKKSVTAEASLGVISGFGYYGYIMAIEFILNNLVRER
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: Y2890_YERPG
Sequence: MFGKGGIGNLMKQAQQMQEKMQQMQEEVAKLEVTGESGAGLVKVTINGAHNCRRVEIDPSLLVEDDKEMLEDLIAAALNDAARRIDETQKEKMASVSNGMQLPPGFKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein YpAngola_A2890.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: QUEF_PROM2
Sequence: MSTAKLDDSTQRPLYGERIIKESKIICFENPNKKRIYEISIDLPEFTCKCPFSGYPDFAKLNIIYQPNLRVYELKSLKLYINNFRDIKISHEEVVNRIMDDLLSAGSPHWIHLNASFNPRGNVSMQLDIFSGQKKN
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: E42_ADES1
Sequence: MELSRIPEGLVCSSGRPYHAKACFKATLHGFCPPFVLQQALKELLTPVLYDQFYCETPLSQKKAHVHRCRNRCVTFYWHCHCSSANSLQCAAAKKVANSVFYHSFIVMQNDNKMCPVPVCCDTWACIPFKPLGIVKQRRCTCYFFVMGGKFETEVLHVASEYSVKFLPFKPNVEIVCVICSCVDSPESCLKRVRRMMNCLRMVMCCSFVNADALQR
What are the official names of this protein?
Protein E4.2.
Protein: HEM3_STAES
Sequence: MRKLIVGSRRSKLALTQSQQFIDKLKFIDPSLDIEIKEIVTKGDKIVDKQLSKVGGKGLFVKEIQNELFNKEIDMAIHSLKDVPSMIPDGLTLGCIPDREIPFDAYIAKNHIPLQELSEGSIVGTSSLRRGAQILSKYPHLKIKWIRGNIDTRLKKLETEDYDAIILAAAGLKRMGWSDNIVTTYLDRDILLPAIGQGALGIECRSDDKELLDLLSKVHNHDVAQCVTAERTFLSEMDGSCQVPIGGYATIAQDNQIEFTGLIMSPDGKERYEHTALGTDPVKLGIEVSQVLKKQGAYDIIKKLNEAE
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: IF2_COXBR
Sequence: MADMSVKQLADLVRTTPERLLEQLKEAGVAITHVDQTISDEEKRKLLLHLKTSHSTETDKKRSKIVLKRKKLSVVKSGKKSVNVEIRSKRTYTKPVVEQKRETEPAPTQEVPLTSDTTNLNEKAEVNVATLEKAVEAEVKEEAKKTPSEKKETPKKGPRKETRRSRKPDKEDKWEREELHMTKLVEERRRRHKPAHMPDSDSASAKLEQGFARPTAPVVREVALPESITVADLAQKMSVKAAEVIKAMMKLGAMVTINQRIDQETAAIVVEEMGHKPKLIKEDVLEENLVATLGEQTGEAVPRAPVVTIMGHVDHGKTSLLDYIRRTKVTSTEAGGITQHIGAYHVETELGMITFLDTPGHEAFTAMRARGAKCTDIVVLVVAADDGVMPQTVEAIQHARAAKVPVVVAVNKIDKPEADPERIKTELSTHDVLPEEWGGDTMFQPISAKTGEGIDALLERILLQAEVLELKAVDNGPARGMVVESRLDRGRGPVATVLVTSGELHLGDILLVGREYGRVRAMIGDDGRPCESAGPSMPVEVLGLSGTSVAGEEAIVVPDERKAREIARFRQGKYREVRLAKKQTAHLERIFDRMGEGKQNTLNIVLKADVQGSLEALTEALNKLSTDEVKVNIIASGVGGITESDVNLAIASDAVVIGFNVRADAPTRVLVEREGVDLRYYSIIYDLIDEVKKALSGLLAPEFEEKIVGLAEVRDVFRSSKIGAIAGCMVVEGVVRRHLPIRVLRDNVVIYEGQLESLRRYKEDVAEVRQGTECGIGVKNYNDVKVGDQIEVYEKTQVHRTIA
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.