PharMolix/UniProtQA huggingface dataset:
Protein: HBB_GADMO
Sequence: MVEWTDSERAIINSIFSNLDYEEIGRKSLCRCLIVYPWTQRYFGGFGNLYNAETILCNPLIAAHGTKILHGLDRALKNMDDIKNTYAELSLLHSDKLHVDPDNFRLLADCLTGVIAAKMVPAFTVDTQVGWQKFRSFVVSALGREYH
What is the function of this protein?
Involved in oxygen transport from gills to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: ISPT_AQUPY
Sequence: MSLKIPEHVAIIMDGNGRWARKRGLPRIAGHYKGAEVAEDIVEFAIELGIKHLTLFAFSTENWNRPKGEVEALFELLRRYLQTKKDKLYKLGIRVRFIGRRDRINKELVKLMQEIEEESKKFKNLFLNLAVDYGGRDDILRAVKKAVKLQREEITEELFSSLLDLSCSPDPDLLIRTAGEKRISNFLLWNLAYTELYFSETLWPDFSREEFLKALEDFSRRKRKFGRVLDE
What is the function of this protein?
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
What are the official names of this protein?
Isoprenyl transferase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: CDO_AJECG
Sequence: MPYLENSESSPDPTPLDAFHCLVQDINKVLGPSSGLDSDDVDPMDIQKLMEDYTSNESEWERYAFGDAGRAYTRNLVDEGNGKCNLLILVWSPGKGSAIHDHANAHCVMKVLKGSLRETLYGWPESDKVQKGEPSPLTVTRDKVYKEGQVTYMSDKLGLHKISNPDPTNFAISLHLYTPPNAAHYGFSLFDEKTGKSRHVKQSVLFSRKGHKL
What are the official names of this protein?
Cysteine dioxygenase, CDO.
What is the protein family that this protein belongs to?
Belongs to the cysteine dioxygenase family.
Protein: CYSH_SHIF8
Sequence: MSKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIHPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDDGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
What is the function of this protein?
Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
What are the official names of this protein?
Phosphoadenosine 5'-phosphosulfate reductase, PAPS reductase, 3'-phosphoadenylylsulfate reductase, PAPS reductase, thioredoxin dependent, PAPS sulfotransferase, PAdoPS reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TATA_RHIME
Sequence: MGSFSIWHWLIVLAVVLLLFGRGKIPELMGDVAKGIKNFKKGMGDDEVASADKSVDGKTVDHKSDEVR
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: TRHO_STAA3
Sequence: MNYQVLLYYKYMTIDDPEQFAQDHLAFCKAHHLKGRILVSTEGINGTLSGTKEETEQYMAHMHADERFKDMVFKIDEAEGHAFKKMHVRPRKEIVALDLEDDVDPRHTTGQYLSPVEFRKALEDDDTVIIDARNDYEFDLGHFRGAIRPNITRFRDLPDWIKENKALFADKKVVTYCTGGIRCEKFSGWLLKEGFEDVAQLHGGIATYGKDPETKGEYWDGKMYVFDDRISVDINQVEKTIIGKDWFDGKPCERYINCANPECNKQILVSEENETKYLGACSYECAKHERNRYVQANNISDNEWQQRLTNFDDLHQHA
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: PXPA_SYMTH
Sequence: MGAIRGPVRKIDLNCDMGESFGVYRIGADEEIMPLITSANIACGFHGGDPQVMRRTVRLAREHGVAVGAHPGYRDLVGFWRRPVRCSPDEVYADVLYQIGALAAFCRAEGVALRHVKPHGALYNTAAADAAIAGAVARAVADFDRSLMLYAPPGSALEQAGLAAGLRVIREGFADRGYAADGTLLPRTHPGAVLHEPERAAAQARGMVCSGTVTADTGEEVAVPAETLCVHGDHPSVIQVLRRIRSELEAAGVSVGAPGAD
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: LEU1_THEFY
Sequence: MIPQQQPSGMPFHRYQPFKPVDLPDRTWPSKTITKAPRWLSTDLRDGNQALIEPMDTERKREIFDLLVRMGYKEIEVGFPAASQTDYDFVRYLIEEDRIPDDVQISVLTQAREELIERTVQSLVGAKRATVHLYNATSPEFRRIVFGVNREECKGIAVEGTRTVLKFAEQYLKDTEYFGYEYSPEIFIDTELEFALEVCEAVMDVYQPGPDREIILNLPATVERATPNVYADQIEWMSRNLSRREYVCLSVHPHNDRGTAVAAAELAVMAGADRVEGCLFGHGERTGNVCLVTLGLNLFSQGIDPMIDFSNIDEIRRTVEHCTQLPVNPRHPYGGDLVYTAFSGSHQDAIKKGFHALEADAAAAGVPVDEYRWNMPYLPIDPKDVGRTYEAVIRVNSQSGKGGVSYVLQRDYSIDLPRRLQIEFSRVVQQFADAEGGEFSGERIWEIFTDTYLSEGVVGVMAYRSETSEDGEYCISADVRLRGEIREITGTGNGPISAFVDALAGVGFKLRVLDYSEHALSEGGDARAAAYVEAEVDGNVLWGVGISSNITTASLKAVCSAVNRAQQS
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
Protein: FADB_YERE8
Sequence: MLYQSETLQLHWLENGIAELVFDAPGSVNKLDTQTVANLGEALVVLEKQSELKGLLLRSAKAAFIVGADITEFLSLFNEPPEKLHQWLVFANDIFNRLEDLPVPTIAAINGYALGGGCECILATDFRVASPEARIGLPETKLGIMPGFGGSVRLPRLLGADSALEIIAAGKDIIAKDALKVGLVDAVVAPEKLVDAALSILNQAIDGKLDWQAARRPKLEPLKLNPTEAAMCFTIAKGMVMQVAGKHYPAPLTAVKTIEAAAKFGRAEALILETNSFVPLAGSNEARALVGIFLNDQYVKGQAKKLSKGVSAPKQAAVLGAGIMGGGIAYQSALKGVPVIMKDINDKSLTLGMNEAAKLLNKQLERGKIDGLKMANILATIQPTLDYAGIERAQVIVEAVVENPKVKAAVLAEVETLIGEETVLASNTSTIPIDQLAKSLKRPENFCGMHFFNPVHRMPLVEIIRGTKTSDKTIAAVVAYATQMGKTPIVVNDCPGFFVNRVLFPYLAGFGMLVRDGADFRQIDKVMEKQFGWPMGPAYLLDVVGIDTAHHAQAVMAVGFPERMNKDYRDAVDVMFDNQRFGQKNGQGFYRYTQDTKGKPRKENDEQVDALLAQVSQPLQKFSDDDIIARTMIPMINEVVRCLEEGIIASPAEGDMALVYGLGFPPFHGGVFRYLDTIGSANYVEMAQRYTHLGALYQVPPGLRAKAEHNESYYPVAAALLDVSISQPA
What is the function of this protein?
Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle.  Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA.  It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
Protein: MRAZ_CUPPJ
Sequence: MFQGASALSLDAKGRMSIPSRHREALQQQAEGRVTLTKHPDGCLLLFPRPEWESFRQRIAALPMDAHWWKRIFLGNAADVEMDGAGRVLIAPELRGAAMLDKEVMLLGMGSHFEVWDAATYAAKEQQAMAQGMPEALKNFSF
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RL6_YERE8
Sequence: MSRVAKAPVVIPAGVEVKLNGQVISIKGKNGELTRTVHSAVEVKQEENTLTFAPREGAVDGWAQAGTTRALLNAMVIGVTEGFTKKLQLVGVGYRAAVKGNVVNLALGFSHPVDHELPAGITAECPTQTEIVLKGADKQVIGQVAADLRAYRRPEPYKGKGVRYADEVVRTKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: CEMA_GUITH
Sequence: MKNWRLNNVTESAFEKTGPIPRSIAKTFEKFKKELEPNSESEIIEEFRVSRYQTASSIKYLVLLVTVPLLINQASKSLVFSPFIDYFWNDNQSDIFLNESQEERAFSELQRFEEKIHFEILIGQSPPLSQETIDKEIKNKAIELAQFYVQESTDAIKNLLADILAFITFAYLIFTGGRQIAVLKSFINELIYGLSDTAKAFLIILFTDIFVGFHSTHGWEVVLENGLRHFGLPENRDLIFLFIATFPVVLDTVFKYWIFRYLNQVSPSAVATYHEMNE
What is the function of this protein?
May be involved in proton extrusion.  Indirectly promotes efficient inorganic carbon uptake into chloroplasts.
What are the official names of this protein?
Chloroplast envelope membrane protein.
What is the protein family that this protein belongs to?
Belongs to the Cema family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: YCF2_ARAHI
Sequence: MKGHQFKSWIFELREIVREIKNSHYFLDSWTQFNSVGSFIHIFFHQERFRKLLDPRILSILLLRNSQGSTSNRYFTIKGVVLFLVAALLYRINNRNMVESKNLYLKGLLPIPMNSIGPRNDTSEESFGSSNINRLIVSLLYLTKGKKISESCFRDPKESTWVLPITKKCIMPESNWSSRWWRNWIGKKRDFCCKISNETVAGIDISFKEKDIKYLEFLFVYYMDDPIRKGHDWELFDRLSPSKRRNIINLNSGQLFEILVKDWICYLMFAFREKIPIEVEGFFKQQGAGSTIQSNDIEHVSHLFSRNKWPISLQNCAQFHMWQFHQDLFVSWGKNPHESDFFRKISRENWIWLDNVWLVNKDRFFSKVRNVSSNIQYDSTRSSFVKVTDSSQLNGSSDQFIDPFDSISNEDSEYHTLINQREIQQLKERSILWDPSFIQTEGREIESDRFPKYLSGYSSMPRLFTEREKRMNNNLLPEESEEFLGNPTRAIRSFFSDRWSELHLGSNPTERSTRDQKLLKKEQDVSFVPSRRSENKEIVNIFKIITYLQNTVSIHPISSDLGYDMVPKDELDMDSSNKISFLNKNPFFDLFHLFHERKRGGYTLRHDFEAEERFQEMADLFTLSITEPDLVYHKGFAFSIDSYGLDQRQFLKEVFNSRDESKKKSLLVLPPIFYEENESFYRRIRKNWVRISCGNYLEDPKPKRVVFASNNIIEAVNQYRLIRNLIQIQFQYSPYGYIRNVLNRFFLMKRPDRNFEYGIQRDLIGNDTLNHRTIMKDTINQHLSNLKKSQKKWFDPLIFLSRTERSINRDPNAYRYKWSNGSKNFQEHLEHFVSERKSRFQVMFDRLCINQYSIDWSEVIDKKDLSKSLRFFLSKLLRFFLSKLLRFLSKLLLFLSNSLPFLFVSFENIPIHRSEIHIYELKGPNDQLCNQLLESIGLQIVHLKKLKPFLLDDHNTSQKSKFLINGGTISPFLFNKIPKWIIDSFHTRKNRRKSFDNTDSYFSIVSHDQDNWLNPVKPFQRSSLISSFSKANRLRFLNNPHHFCFYCNKRFPFYVEKAHLNNSDFTYGQFLTILFIHNKIFSSCGGKKKHAFLERDTISPSSIESQVSNIFISNDFPQSGDERYNLYKSFHFPIRSDPLVRRAIYSIADISGTPLIEGQRVNFERTYCQTLSDMNRSDSEEKSLHQYLNFNSNMGLIHTPCSEKYLQRKKRSLRLKSLKRCVDKGQLDRTFQRDSAFSTLSKWNLFQTYMPWFFTSTGYKYLNLIFLDTFSDLLRILSSSQKFVSIFHDIMHGLDISWRILQKKLCLPQRNLISEISSKSLHNLLLSEEMIHRNNESSLISIHLRSPNVREVLYSILFLLLVAGYIVRTHLLFVSRAYSELQTEFEKIKSLMIPSYMIELRKLLDRYPTSELNSFWLKNLFLVALEQLGDCLEEIRGSGGNMLWGGDPAYGVKSIRSKKKDLKINFIDIIDLISIIPNPINRITFSRNTRHLSHTSKEIYSLIRKRKNVSGDWIDDKIESWVANSDSIDDKEREFLVQFSTLRAEKRIDQILLSLTHNDHLSKNDSGYQMIEQPGTIYLRYLVDIHKKYLMNYEFNTSCLAERRIFLAHYQTITYSQTSCGANSFHFPSHGKPFSLRLALSPSRSVLVIGSIGIGRSYLVKYLATNSYVPFITVFLNKFLDNKPKGFFIDDIDIDDSDDIDASNDIDRELDTELELLTMMNALTMDMMSEIDRFYITLQFELAKAMSPCIIWIPNIHDLDVNESNYLALGLLVNSLSRDCERCSTRNILVIASTHIPQKVDPALIAPNKLNTCIKIRRLLIPQQRKHFFTLSYTRGFHLEKKMFHTNGFESITMGSSARDLVALTNEALSISITQKKSIIDTNTIRSALHRQTWDLRSQVRSVQDHGILFYQIGRAVAQNVLISNCPIDPISIYMKKKSCNEGDSYLYKWYFELGTSMKKFTILLYLLSCSAGSVAQDLWSLPGPDEKTRITSYGFIENDSDLVHGLLEVQGALVGSSRTEKDCSQFDNDRVTLLFRSEPRDPLYMMQDGSCSIVDQRFLYEKYESEFEEGEGEGVLDPQQIEEDLFNHIVWAPRIWRPRGFLFDCIERPNELGFPYLAGSFRGRRIIYDEKYELQENDSEFLQSGTMQYQRRDRSSKEQGFFRISQFIWDPADPLFFLFKEQPFVSVFSHREFFADEEMSKGLLTSQTDPPTSIYKRWFIKNTQEKHFELLIQRQRWLRTNSSLSNGFFRSNTLSESYQYLSNLFLSNGTLLDRMTKTLLKKRWLFPDEMKIGFM
What is the function of this protein?
Probable ATPase of unknown function.  Its presence in a non-photosynthetic plant (Epifagus virginiana) and experiments in tobacco indicate that it has an essential function which is probably not related to photosynthesis.
What are the official names of this protein?
Protein Ycf2.
What is the protein family that this protein belongs to?
Belongs to the Ycf2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: NUOCD_AZOVD
Sequence: MTADSVLSIPPYKADDQDVVAELNSRFGAETFTVQSTCTDMPVLWVAREKLIEVLRFLRNLPRPYVMLYDLHGVDERLRTQRRGLPEADFSVFYHLLSIERNSDVMIKVALKEGDLKLPSATGIWPNANWYEREIWDMYGIHIEGHPHLTRILMPPTWEGHPLRKDYPARATEFDPYSLSAAKQDLEQEALRFKPEEWGMKRGGEHEDFMFLNLGPNHPSAHGAFRIILQLDGEEIVDCVPEIGYHHRGAEKMAERQSWHSFIPYTDRIDYLGGVMNNLPYVLAVEKLAGIKVPQRVDVIRVMMAEFFRILNHLLYLGTYIQDVGAMTPVFFTFTDRQRAYKVVEAITGFRLHPAWYRIGGVAHDLPRGWDALVKEFVEWMPKRLDEYEKAALQNSILRGRTMDVARYDTRQALEWGVTGAGLRATGLDFDLRKARPYSGYENFEFEVPLAHNGDAYDRCMVKLGEMRQSLRIIEQCRRNMPEGPYKADHPLTTPPPKERTLQHIETLITHFLQVSWGPVMPANESFQMIEATKGINSYYLTSDGSTMSYRTRIRTPSYAHLQQIPSVIRGSMVADLIAYLGSIDFVMADVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SYD_SALA4
Sequence: MRTEYCGQLRLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGIVQVFFDPDRADALKLASELRNEFCIQVTGTVRARDAKNVNADMATGEIEVLASSLTIINRADSLPLDANHVNTEEARLKYRYLDLRRPEMAQRLKTRAKITSLVRRFMDEHGFLDIETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDVETSFMTAPQVREVMEALVRHLWLEVKGVDLGDFPVMTFAEAERRYGSDKPDLRNPMELVDVADLLKSVEFAVFAGPANDPKGRVAALRVPGGAQLSRKQIDDYGNFVKIYGAKGLAYIKVNERAKGLDGINSPVAKFLTADIVDAILERTGAQDGDMIFFGADNKKVVADALGALRLKLGKDLSLTDEDKWAPLWVIDFPMFEDDGEGGLTAMHHPFTAPRDMTASELKTAPEEAVANAYDMVINGYEVGGGSVRIHNGEMQQTVFGILGINEQEQREKFGFLLDALKYGTPPHAGLAFGLDRLTMLLTGTDNIRDVIAFPKTTAAACLMTEAPSFANQAALTELGIQVVKKAENN
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HMN4_HUMAN
Sequence: MATQGFSCLLLSVSEIDLSMKRQYKQIR
What is the function of this protein?
Plays a role as a neuroprotective and antiapoptotic factor.
What are the official names of this protein?
Humanin-like 4, HN4, MT-RNR2-like protein 4.
What is the protein family that this protein belongs to?
Belongs to the humanin family.
What are the subcellular locations of this protein?
Secreted. Cytoplasm.
Protein: TTCA_XANOP
Sequence: MTAVLPLPHPLADPAPRDPRQRLQREQLRLGKRLQRQVGQAIADFGMISPGDKIMVCLSGGKDSYTMLDMLLQLQRKAPVPFTLVAVNLDQKQPDFPAHVLPAYLDALGVPFDIVEQDTYSVVSRVVPAGKTMCSLCSRLRRGALYAYAQTHGVTKIALGHHRDDIVATFFMNLFHHARLAAMAPKLRSDDGAHVVIRPLAYVREAHIAAYAQARQFPIIPCNLCGSQENLQRQQVGKMLQQWDHEQPGRVEQIARALGDVRPEQLADRTLFDFLALGRSGDAPPDLAPDPGAWLTASDATHDSD
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: I17RD_CHICK
Sequence: MAPGRELGAFLLALLAFCGGRRLAEAAGGPGGRRGAAADACGGRGLSSVTKSNGLLNITFKYDNCTPYLNSVGKHVIGDVQNITISQYACYEQVAVTILWTANAIGIEYLRGFRVILEELKSEGRQCQQMVLRDPKQLSPSFKRTGMESNPFANLKFETDYFVKIVPFPSIKNESNYHPFFFRTRPCELLLQPENLICKPYWKPRNLNVTQQGFNMQVSFDHAPHNFGFRYYFLHYKLKHEGPFKQKTCKQDQNTDTTSCILQNVTPGDYIIELVDDTNTTRKTMHYALKPVHSPWAGPIRAIAITVPLVVISAFATLFTVMCRKKQQENIYSHLDEESSESSAYGAGLPVERLRPRPKVFICYSSKDCQKHINVIQCFAYFLQDFCGCEVALDLWEDLKICKESQKEWLIKKINESQFIIIVCSKGMKYFVEKKNWKHRGVTKDTGKGELFLFAVFTVAEKLRQAKQNSNDLCKFIAVYFDYSCEGDIPGILDLSTKYKLMDNLPQLYSHLHSRDLSVQDSEVFPVNVSKRNYFRSKSGRSLYVAICNMHQFIDQEPDWFEKQFIPFLPHPLHYSEPVMEKFDSGLVLNDLVNKQAADDDFYLKTDVNIISAGSSDSHCIIQHLNLGEDVETQDIQRGGSSVLRPLLHAVKASNLKDMPRDSGIYDSSVPSSELSLPLMEGLLTDQTETSSITGSVSSSSGLGEEEPPVITSTKFLLPGICKAELHCHIHTDELQAIAPL
What is the function of this protein?
Feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation.  May inhibit FGF-induced FGFR1 tyrosine phosphorylation (By similarity).  Inhibits TGFB-induced epithelial-to-mesenchymal transition in lens epithelial cells (By similarity).
What are the official names of this protein?
Interleukin-17 receptor D, IL-17 receptor D, IL-17RD, Sef homolog, cSEF.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RECX_ECOSE
Sequence: MTESTSRRPAYARLLDRAVRILAVRDHSEQELRRKLAAPIMGKNGPEEIDATAEDYERVIAWCHEHGYLDDSRFVARFIASRSRKGYGPARIRQELNQKGISREATEKAMRECDIDWCALARDQVTRKYGEPLPTVFSEKVKIQRFLLYRGYLMEDIQDIWRNFAD
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2868_CLOBJ
Sequence: MDNNVDTITLTDEEGKETEFEVITKLDIEDKEYVVVVPKNEEVDEAIALRIDNNDDGEEVLVPVEEDEEFNMVAEAYELLFSEE
What are the official names of this protein?
UPF0473 protein CLM_2868.
What is the protein family that this protein belongs to?
Belongs to the UPF0473 family.
Protein: AROQ_CLOB8
Sequence: MKIMVINGPNLNMVGVREKGIYGAKSFEDICEYIKEEGKKRGHEITLFQSNCEGEIIDELQKAYFENYDGIIINPGAYTHYSYAIHDAIKGINIDTVEVHLSNVHAREDFRKKSVTAPACIGQMCGFGEDGYILAIKALELKKMSK
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: RL3_PROMT
Sequence: MSLGILGKKLGMSQLFDDQGRAVPVTLIEAGPCRITQLKSADTDGYAAVQIGFQLIREKLINKPSKGHLAKSGNDLLRHLREYRVENSSEFELGASITVDDFEKGQKVDISGDTMGRGFAGYQKRHGFSRGPMSHGSKNHRLPGSIGAGTTPGRVYPGKRMAGRMGGKKVTTRALEILKIDTNHNLLVVKGSVPGKPGSLLNIRPAKRVGAPTQQGGK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: HIR3_YARLI
Sequence: MSSFIPLNALEDYSLSSAEEHTRELQIEEGLKIFQKALHAQRQGKLDEAFDLYDALFKIDVIHLDIDDNNLSPTVGRLKYLAYKNHGILLLEHLAHNLDDLTTTEIRDQLQDILVQFADALLVDDSDDSFLKLFSDLARIIGLKRLSRFALECIVSSPSRVFTFSESLLNHDFLNPEEVAILQEVVLLAKQLQDYVSMDSPMYDLMASQVADVAPAKKPKYISWIEPTQFKAPPLKDLKETWRGSELVVEIGVPSWRGICKGLHDSLHRLTKRKKVLNGVTIRDPYLQIGVEISSVHGKLVDEEDLEDPEDDVEMMDIIDKPAEETIEVKTEEALDSTVKVEEIPAEINIGEVENKSSTEENKKQESPENGDKKEASGNGNGSAGPPVKDTTVKTEDRDSLTVALAIKRPAEGTTSSSQPPSKRTRGRGADEPAELEKQVDPGFFNNITSFVGSLDLKFPFVDLNQLDNEEQFYQDFKAVISNWGEQGSELFLKLSSAPESNLSVPVTQILDSAAQVDDDYGAPCNVLSISPDKFLEQMSESCSLSDFRFKIIEALLGNSSLVNEIWPSELIASVQIILNHLEPQILRDVRQMFFDGQTHSDSLIKQQLYVAEARYELVANEIIADKQRITENTSKLTKSALRDREWHKKTLHQRLLAWESCVITLLSMCKTRQLSVTELELRHTWVRLSLSQCDEAEISRMRQNYEEFQVQLLDEAPDLMVRFVNFPHIQTLSLDSVNGQISKLKVASTFAKIFSPDADEDIGTRIAMLESILKGSSDTSGDRESLSAREFLQHASIDFKHKLWYLLLDAYNESGEKRISVDGYIEMLTSLSYELETAGYRNMNPNQRHTILLRTLSTMNDTVGNLAKICRDTPALLESVSREKIHELAQLCLSFLRLLQVFNQFYDRRNPEEPTPFLWDKASEKFQTMMVKLWTFFYLLFRQLTNGLDENLPQTTISTLNDILSIVHEDLGHRKCCSFANGIFVDLTLDEIVRMKWNESEADLLQNIRCRFGIQLANEHYHPTDHGATPRALKRSDGLAFQDFIMNMVYRKPSSVHNIRADLRAVMDQLYEAIGDPDKNIASTSHNMTVLGRFTVAPVTWNYIENSLRGESFLPFMTSTDPVLSASTGGFYCVQGMLALAKFRQGKKAAAPGRTEDLQAAVKFFTNDILCCPTRYESWFGIANAYEMLTEDDLMWSAEKLDVPNSIVNINQRKALLCGLNSVNLMLQQRDEKPANPQLRTFFNAVMKESQWLFLSKLFYSATANPLHGASFRQADNKIFCGMKGLYMRQNLSLPRRKQCYQVVRACLTISINSKDQPPDWYSYYLRSKVYSKLKKTTQAILGDIQKSIAVAPDKINGDILLEPHYKLVAYLYKAVKRGKLTAAEAYKELKKTPHFVEYLGEDADMESGDDSDSDSEVGSDSETESTKEGPIASATEPAADTAPPVVPSEGTSGSPISIDDATPVPGPVTAVTAIAAPPTVAAKPEEKKKPLTRMEIKFYKSCIETLRRMKVLDKRKWHHRPPFLIARIHKEVFEDYRSAKEEMVPFFNLKNQSKAPVHIWKPDFERAGKHFQYVFDYLMFFIVLLDKTDDTDAITTIGKKLRRFNNGMVNHFEVWEFTCLTSNVLMKRVTRIPEKLPDAIIPSLQFDNFDRIAQGLQDKITKSKEPASYLLSLLYYASEFRRLNNGFGSTGVVDDTVVCLYLKMLIEYAGTSLLADNKSRSSTPVVLDGAKFEFQPGSAQPPALPAPATTATTAGKKEDGKKEKTRVTRKDILLRATNLIKACSNKVGENIKLVTTKGPPAVASSNGSSSNSGTRSNSEEKEKEPTEEPEKSTQDSDVEMADANQGNTETTVEPEAEGEADKSAEEDKSDKSAEEEKTDKFAEEEKSASAEPAGKNTPKSKSTGSNGVITIDEEYSAPE
What is the function of this protein?
Has a role in a nucleosome assembly pathway that is required for the integrity of heterochromatin and proper chromosome segregation.
What are the official names of this protein?
Histone transcription regulator 3 homolog.
What is the protein family that this protein belongs to?
Belongs to the HIR3 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DYL5B_XENLA
Sequence: SDIAKDKAARLLKKRGSISSLGSHDVKPRGSFSKTKDSVSTVSYIDEPGHHDDIQRPAILVENTYQMGPTKRFPVASVNNILKDVLTSYLQEEKYEAELCRQMTKTISEVIKARVKDLMIPRYKIIVLIYIGQLNDQGMRVGSRCIWDPANDTFSSYSFKNSSLFALANVYGVYYE
What are the official names of this protein?
Dynein light chain Tctex-type 5-B, Tctex1 domain-containing protein 1-B.
What is the protein family that this protein belongs to?
Belongs to the dynein light chain Tctex-type family.
Protein: OTRA_STRRM
Sequence: MNKLNLGILAHVDAGKTSLTERLLHRTGVIDEVGSVDAGTTTTDSMELERQRGITIRSAVATFVLDDLKVNLIDTPGHSDFISEVERALGVLDGAVLVVSAVEGVQPQTRILMRTLRRLGIPTLVFVNKIDRGGARPDGVLREIRDRLTPAAVALSAVADAGTPRARAIALGPDTDPDFAVRVGELLADHDDAFLTAYLDEEHVLTEKEYAEELAAQTARGLVHPVYFGSALTGEGLDHLVHGIRELLPSVHASQDAPLRATVFKVDRGARGEAVAYLRLVSGTLGTRDSVTLHRVDHTGRVTEHAGRITALRVFEHGSATSETRATAGDIAQAWGLKDVRVGDRAGHLDGPPPRNFFAPPSLETVIRPERPEEAGRLHAALRMLDEQDPSIDLRQDEENAAGAVVRLYGEVQKEILGSTLAESFGVRVRFDPTRTVCIEKPVGTGEALIELDTRTHNYFWGAPWVCASDRPSPARAITFRLAVELGSLPLAFHKAIEETVHTTLRHGLYGWQVTDCAVTLTRTGVRSPVSAADDFRKANARLVLMDALGRAGTEVHEPVSSFELEVPAARLSPVLAKLAELGATPGVPTAEGDVFRLEGTMPTSLVHDFNQRVPGLTQGEGVFLAEHRGYRPAVGQPPVRPRPEGPNPLNRDEYILHVLKRV
What is the function of this protein?
Abolishes the inhibitory effect of oxytetracycline on protein synthesis by a non-covalent modification of the ribosomes.
What are the official names of this protein?
Oxytetracycline resistance protein.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. TetM/TetO subfamily.
Protein: VATF_CAEEL
Sequence: MASAAKGKILAVIGDEDTVVGFLLGGVGELNKARKPNYLIVDKQTTVQEIEEAFNGFCARDDIAIILINQHIAEMIRYAVDNHTQSIPAVLEIPSKEAPYDPSKDSILNRARGLFNPEDFR
What is the function of this protein?
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).  Required along with other vacuolar ATPase components for the removal of protein aggregates which form in immature oocytes in the distal gonad (PubMed:29168500).  This removal occurs as the oocytes mature and move to the proximal gonad, is triggered by the introduction of sperm through mating and occurs before fertilization (PubMed:29168500).  The introduction of sperm triggers V-ATPase accumulation in proximal oocytes and induces lysosomal acidification which leads to engulfing of protein aggregates by lysosomes and subsequent clearance of the aggregates (PubMed:29168500).  Lysosomal acidification also leads to changes in mitochondrial morphology and function (PubMed:29168500).  Mitochondria in distal immature oocytes are fragmented, produce high levels of reactive oxygen species (ROS) and have high membrane potential, indicative of metabolic inactivity (PubMed:29168500).  In contrast, mitochondria in proximal mature oocytes are tubular with lower ROS levels and membrane potential, indicative of an active metabolic state required for aggregate mobilization before clearance (PubMed:29168500).
What are the official names of this protein?
Probable V-type proton ATPase subunit F, V-ATPase subunit F, Vacuolar proton pump subunit F.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase F subunit family.