PharMolix/UniProtQA huggingface dataset:
Protein: MIAB_VIBCH
Sequence: MSKKLLIKTWGCQMNEYDSSKMADLLNAANGYELTEIPEEADVLLLNTCSIREKAQEKVFHQLGRWKTLKDKKPGVVIGVGGCVATQEGDSIRDRAPYVDVIFGPQTLHRLPEMIKQSQTSDAPVMDISFPEIEKFDRLPEPRAEGPTAFVSIMEGCSKYCTYCVVPYTRGEEVSRPMDDVLFEIAQLAEQGVREVNLLGQNVNAYRGATHDGGICSFAELLRLVATIDGIDRIRFTTSHPLEFTDDIIAVYEDTPELVSFLHLPVQSGSDRILTMMKRPHTAIEYKSIIRKLRKARPDIQISSDFIVGFPGETDKDFQDTMKLIRDVDFDMSFSFIFSPRPGTPAADYPCDLSEEVKKERLYELQQQINSQAMRYSRLMLGTEQRILVEGPSKKDLMELRGRTENNRVVNFEGSPDLIGQFVDVKIVDVFPNSLRGELLRTEQEMNLRIATSPSEMKAKTRREDELGVATFTP
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2593_MYCBO
Sequence: MGGLTISDLVVEYSSGGYAVRPIDGLSLDVAPGSLVILLGPSGCGKTTLLSCLGGILRPKSGSIKFDDVDITTLEGAALAKYRRDKVGIVFQAFNLVSSLTALENVMVPLRAAGVSRAAARKRAEDLLIRVNLGERMKHRPGDMSGGQQQRVAVARAIALDPQLILADEPTAHLDFIQVEEVLRLIRSLAQGDRVVVVATHDSRMLPLADRVLELMPAQVSPNQPPETVHVKAGEVLFEQSTMGDLIYVVSEGEFEIVRELADGGEELVKTAAPGDYFGEIGVLFHLPRSATVRARSDATAVGYTAQAFRERLGVTRVADLIEHRELASE
What are the official names of this protein?
Uncharacterized ABC transporter ATP-binding protein Mb2593.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: SERC_ACIAD
Sequence: MRAYNFCAGPAALPTAVLEKAQQELLDWQGKGLSIMEMSHRSKDYVAVAEKAEADLRKLMNIPENYQVLFLQGGASLQFSAIPMNLLGKNSKADYIHTGIWSEKALKEAQRYGDINVIEAGTSIDGKLAIKNQSEWNLSQDAAYVHYAENETIGGIQFADIPDVNVPLVSDLSSSILSAPLDVSKFGLIYAGAQKNIGPAGLTIVIVRDDLLDQSRSDIPSILKYSAQAKNGSMVNTPATYAWYLSGLVFEWLLEQGGVDAIHQVNLEKAKLLYGYIDSSDFYNNPIAVPNRSIMNVPFTLADEALEKLFLQEAEENHLLNLAGHRSVGGMRASIYNAVPLEGVQALVNFMDTFVQKHG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FHL1_MOUSE
Sequence: MSEKFDCHYCRDPLQGKKYVQKDGRHCCLKCFDKFCANTCVDCRKPISADAKEVHYKNRYWHDNCFRCAKCLHPLASETFVSKDGKILCNKCATREDSPRCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWHAECFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHNEQVYCPDCAKKL
What is the function of this protein?
May have an involvement in muscle development or hypertrophy.  Isoform 2 binds to RBP-J and plays a negative regulatory role in the RBP-J-mediated transcription in mammalian systems.
What are the official names of this protein?
Four and a half LIM domains protein 1, FHL-1, KyoT, RBP-associated molecule 14-1, RAM14-1, Skeletal muscle LIM-protein 1, SLIM, SLIM-1.
What are the subcellular locations of this protein?
[Isoform 1]: Cytoplasm. SUBCELLULAR LOCATION: [Isoform 2]: Nucleus.
Protein: RPC5_MOUSE
Sequence: MANEEDDPVIQEIDVYLAKSLAEKLYLFQYPVRPASMTYDDIPHLSAKIKPKQQKVELEMAIDTLNPNYCRSKGEQIALNVDGACADETSTYSSKLMDKQTFCSSQTTSNTARYAAALYRQGELHLTPLHGILQLRPSFSYLDKADAKHREREAANEAGDSSQDEAEEDVKQITVRFSRPESEQARQRRVQSYEFLQKKHAEEPWVHLHYYGMRDSRSEHERQYLLCQGSSGVENTELVKSPSEYLMMLMPPSPEEEKDKPVAPSNVLSMAQLRTLPLADQIKVLMKNVKVMPFANLMSLLGPSVDSVAVLRGIQKVAMLVQGNWVVKSDILYPKDSSSPHSGMPAEVLCRGRDFVMWKFTQSRWVVRKEVAAVTKLCAEDVKDFLEHMAVVRINKGWEFLLPYDLEFIKKHPDVVQRQHMLWSGIQAKLEKVYNLVKETMPKKPDGQSAPVGLVSGEQRVQTAKTKAQQNHAFLERELQRRKEQMRAATVLPSVQIKEEPLSEEEADGAELEAEEEEPMDTAPSTCLSTKLANGLPAGRAVGGDSLNGHPVPGCASNPVACELKAFVEATFQRQFVLTLSELKRLFNLHLAGLPPGHILFSGVSDRMLQDTVLAAGCKQILVPFPPQTAASPDEQKVFALWESGDMSDQHRQVLLEIFSKNYRVRRNLIQSRLTQECGEELSKQEVDKVLKDCCVSCGGMWYLKGTVQS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Specific periphjeric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.  Essential for efficient transcription from both the type 2 VAI and type 3 U6 RNA polymerase III promoters.  Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses.  Acts as nuclear and cytosolic DNA sensor involved in innate immune response.  Can sense non-self dsDNA that serves as template for transcription into dsRNA.  The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase III subunit RPC5, RNA polymerase III subunit 5, RNA polymerase III subunit C5, Sex-lethal interactor homolog, Sxl interactor.
What are the subcellular locations of this protein?
Nucleus.
Protein: GRF6_ARATH
Sequence: MATRIPFTESQWEELENQALVFKYLAANMPVPPHLLFLIKRPFLFSSSSSSSSSSSFFSPTLSPHFGWNVYEMGMGRKIDAEPGRCRRTDGKKWRCSKEAYPDSKYCERHMHRGKNRSSSRKPPPTQFTPNLFLDSSSRRRRSGYMDDFFSIEPSGSIKSCSGSAMEDNDDGSCRGINNEEKQPDRHCFILGTDLRTRERPLMLEEKLKQRDHDNEEEQGSKRFYRFLDEWPSSKSSVSTSLFI
What is the function of this protein?
Transcription activator that plays a role in the regulation of cell expansion in leaf and cotyledons tissues.
What are the official names of this protein?
Growth-regulating factor 6, AtGRF6, Transcription activator GRF6.
What is the protein family that this protein belongs to?
Belongs to the GRF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NIPA4_MOUSE
Sequence: MELRVANANGSCENGSIVSLYCSSQEVLCQIVRGISPEEPYNATLITWQERVRKKYGFYIGVGLAFLSCFLIGTSVILKKKGLIRLVATGATRAVNGGYGYLKDPMWWAGMATMSAGEVANFGAYAFAPATVVTPLGALSVLISAIFSSYCLGESLNLLGKLGCVICMAGSTVMVIHAPKEEKVTTVAEMASKMKDTGFIVFAVLLVVSCLILIFIVAPRYGQRNILIYIIICSVIGSFSVTAVKGLGVTIRNFFQGLPVVRHPLPYILSLILGLSIIIQVNFLNRALDIFNTSLVFPIYYVFFTTVVVASSIVLFKEWYTMSAVDIVGTLSGFVTIILGVFMLHAFKDLDINQISLPHTHKNPTPAPAPEPTVIKLEDKNVLVDNIELASTPSPQQKPKVFMTDS
What is the function of this protein?
Acts as a Mg(2+) transporter.  Can also transport other divalent cations such as Ba(2+), Mn(2+), Sr(2+) and Co(2+) but to a much less extent than Mg(2+).  May be a receptor for ligands (trioxilins A3 and B3) from the hepoxilin pathway (By similarity).
What are the official names of this protein?
Magnesium transporter NIPA4, Ichthyin, NIPA-like protein 4, Non-imprinted in Prader-Willi/Angelman syndrome region protein 4 homolog.
What is the protein family that this protein belongs to?
Belongs to the NIPA family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FBX9_MOUSE
Sequence: MSAEAEEDCHSDADRVGDEGNESPAERDLQAQLQMFRAQWMFELTPGVGSSHGETRPCRAGRSSMLKAAADTKGRQELAKEEKARELFLQAVEEEQNGALYEAIKFYRRAMQLVPDIEFKITYTRSPDGDGVGSGYIEENEDASKMADLLSYFQQQLTLQESVLKLCQPELETSQTHISVLPMEVLMYIFRWVVSSDLDLRSLEQLSLVCRGFYICARDPEIWRLACLKVWGRSCMKLVPYASWREMFLERPRVRFDGVYISKTTYIRQGEQSLDGFYRAWHQVEYYRYMRFFPDGHVMMLTTPEEPPSIVPRLRTRNTRTDAILLGHYRLSQDADNQTKVFAVITKKKEEKPLDHKYRYFRRVPVQEADHSFHVGLQLCSSGHQRFNKLIWIHHSCHITYKATGETAVSAFEIDKMYTPLLFARVRSYTAFSERPL
What is the function of this protein?
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins and plays a role in several biological processes such as cell cycle, cell proliferation, or maintenance of chromosome stability.  Ubiquitinates mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation.  In contrast, does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex.  As a consequence, mTORC1 is inactivated to restrain cell growth and protein translation, while mTORC2 is the activated due to the relief of feedback inhibition by mTORC1 (By similarity).  Plays a role in maintaining epithelial cell survival by regulating the turn-over of chromatin modulator PRMT4 through ubiquitination and degradation by the proteasomal pathway (By similarity).  Regulates also PPARgamma stability by facilitating PPARgamma/PPARG ubiquitination and thereby plays a role in adipocyte differentiation (PubMed:23643813, PubMed:27197753).
What are the official names of this protein?
F-box only protein 9.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARNB_SALHS
Sequence: MSDFLPFSRPAMGAEELAAVKTVLDSGWITTGPKNQELEAAFCRLTGNQYAVAVSSATAGMHIALMALGIGEGDEVITPSMTWVSTLNMIVLLGANPVMVDVDRDTLMVTPEHIEAAITPQTKAIIPVHYAGAPADLDAIYALGERYGIPVIEDAAHATGTSYKGRHIGARGTAIFSFHAIKNITCAEGGIVVTDNPQFADKLRSLKFHGLGVDAWDRQSGGRAPQAEVLAPGYKYNLPDLNAAIALAQLQKLDALNARRAAIAAQYHQAMADLPFQPLSLPSWEHIHAWHLFIIRVDEARCGITRDALMASLKTKGIGTGLHFRAAHTQKYYRERFPTLTLPDTEWNSERICSLPLFPDMTESDFDRVITALHQIAGQ
What is the function of this protein?
Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase, UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase, UDP-Ara4O aminotransferase, UDP-4-amino-4-deoxy-L-arabinose aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.
Protein: PDXJ_PHOV8
Sequence: MTKLSVNINKVATLRNARGGNNPDVVKVALDCEAFGAEGITVHPRPDERHIRRSDVYELRPLLTTEFNIEGYPSPEFVDLVLKVKPHQVTLVPDAPDQITSNAGWDTKTNLSFLTELMDTFGQAGIRTSIFVGTDKEMIEYAAKAGADRVELYTEPYATMYPRNPEAAIAPFIEAAKVTRSLGMGLNAGHDLSLVNLKYMHTHIPWLDEVSIGHALISDALYMGLKQTIEEYKNCLRS
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_XYLFT
Sequence: MTHVPVLYTQAMEGLRVVENGTYLDGTFGRGGHARGVLQQLGPGGRLLVMDKDPEAIAMAERAFSCDPRVVIRHGSFALLAQLAAPQSLDGVLFDLGVSSPQLDVPERGFSFAKDGPLDMRMDPEMGESAAQWLARVSEREIADVLWTYGEEKQSRRIARAIVAYRANQPLLRTVQLAELIASVMLRTKFGACKSRIHPATRSFQGIRIHVNRELVDLEVGLEAALAALRPGGRLVVISFHSLEDRIVKQFISRHSKVPPTNRRLPEVQTFVPLLRMIGRAIKADEDELEVNPRARSAVLRVAEKLDVLGAVR
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_BRADU
Sequence: MFAVIKTGGRQYRVAPDDVLEVGKIEGEVGSIVQLNEVLVVGGDTPILGLPTVAGASVAVEVLDHKRGPKVIAFKKRRRKNSRRKRGYRDEITVLRVSEILTDNAKPTKGPRPKKEKVAKEATKEDAAA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: BCL3_MOUSE
Sequence: MPRCPAGAMDEGPVDLRTRPKGTPGAALPLRKRPLRPASPEPATTRSPAGPLDALRSGCDVPVVPGPPHCVARPEALYYQGPLMPIYSTPTMAPHFPLLNLPTHPYSMICPMEHPLSADIAMATRVDEDGDTPLHIAVVQNNIAAVYRILSLFKLGSREVDVHNNLRQTPLHLAVITTLPDMVRLLVTAGASPMALDRHGQTAIHLACEHRSPSCLQALLDSATSGSVDLEVRNYEGLTALHVAVNTGCQEAVLLLLERGADIDAVDIKSGRSPLIHAVENNSLNMVQLLLLHGANVNAQMYSGSSALHSASGRGLLPLVRTLVRSGADSGLKNCHNDTPLMVARSRRVIDILRGKASRAASGSQPEPSPDQSATNSPESSSRLSSNGLQSSPSSSPSLSPPKDAPGFPATPQNFFLPTTSTPAFLPFPGVLRGPGRPVPPSPAPGSS
What is the function of this protein?
Contributes to the regulation of transcriptional activation of NF-kappa-B target genes.  In the cytoplasm, inhibits the nuclear translocation of the NF-kappa-B p50 subunit (By similarity).  In the nucleus, acts as transcriptional activator that promotes transcription of NF-kappa-B target genes.  Contributes to the regulation of cell proliferation.
What are the official names of this protein?
B-cell lymphoma 3 protein homolog, BCL-3.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, perinuclear region. Note=Ubiquitination via 'Lys-63'-linked ubiquitin chains is required for nuclear accumulation.
Protein: ETR1_KLULA
Sequence: MSSFLSKRFLSFSQRAMSQESLKFKSLIYSSHDSQDCTKVLKVHNYKPKKGSETSIVLKTLAFPINPSDINQLEGVYPSKPDKVTDYSTDEPSAIAGNEGVFEVVSVPSSVSTLKPGDKVIPLQANFGTWSTYRTCDKESDLIKIEGVDIYTAATVAVNGCTAYQLVNDYINWDPKGNDWLVQNAGTSSVSKIVTQIAKAKNINTLSVIRDRENFEEVAEILEKKYGATKVISETENGEKEFGKEVLPKVLGSNAQVKLALNSVGGKSCANIARKLSKDGLMLTYGGMSKQPLTFPTGLFIFKGLKSHGFWVTENSKRDPENKIKTVNEVIELYRDGKIISPKEDIRALEWDVNNASDEEVLQLITDGIKTKGTKNMVILKW
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of trans-2-enoyl thioesters in mitochondrial fatty acid synthesis (fatty acid synthesis type II).  Fatty acid chain elongation in mitochondria uses acyl carrier protein (ACP) as an acyl group carrier, but the enzyme accepts both ACP and CoA thioesters as substrates in vitro.  Required for respiration and the maintenance of the mitochondrial compartment.
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase, mitochondrial, 2-enoyl thioester reductase.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: DNLJ_PORGI
Sequence: MEKIVPPAVRIEELRRILREHEYRYYVLSSPTIDDFEYDAMMKQLEELEREYPEWDSPDSPTHRVGSDKTEGFASVRHDRPMLSLSNTYNYDEIGDFYRRVSEGLQGAPFEIVAELKFDGLSISLIYEDGMLVRAVTRGDGIMGDDVTANVRTIRSVPLRLRGDDYPRMLEVRGEILLPFKEFDRINAQREAEGEPLFANPRNAASGTIKQLDPHIVAGRNLDAYFYYLYSDEPLAENHYDRLMQARQWGFKVSDAVTLCCSKEEVYAFIDRFDTERLTLPVATDGIVLKVNAPAQQDLLGFTAKSPRWAIAYKYQAERVRTRLQHVSYQVGRTGAVTPVANLDPVLISGTVVRRASLHNADFIAEKDLHEGDFVYVEKGGEIIPKIVGVDTDARSIDGRPIVFTVLCPDCATPLVREQGEAAYYCPNAEGCPQQQKGRLEHYCGRKTADINIGPETIELLYSRNMIRNVADFYALTEEQLLTLPGFKKRAAAKLLDSIEASKARPYQAILFGLGIRFVGETVAKKLAAVYPSIDALAAATSEELVQIDEIGERIAAAVLHFFSLRQNRELIERLRLAGVSLEAETVSVAVSNRLAGKTVVISGTFEKRSRDEYKAMVEDNGGRMAGSVSSKTSFILAGSDMGPSKREKAEKLGVRLMSEEEFLRLIEE
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: Y2186_MARN8
Sequence: MPIWVDADACPVPIREILCRAATRWQIQTTFIANHAISLPPSPHISRRQVPHGFDVADNEIMDQMSKGDLVITQDIPLAAEAIEKGADVFNPRGQAFTKENIRQRLAMRNFMEEMRNAGQVTGGPAPFSQGDRKEFADQLDRWLQRNARK
What are the official names of this protein?
UPF0178 protein Maqu_2186.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: SPT21_MACFA
Sequence: MDNRNTQMYTEGRIKVPGTQPSPGLRITIKRAGVEPTIPGVSQVMFPDASEVGSRKQLSSASGGPEKGPRYRDTFKEGPSELRTQEQRPPAKPGKKQSSWVPQEGSQELQAGQDQSELGLLPSWVPEGPEGLQQLGSGKEIEGQQRRQRNRGTGEDEPPESCQGPGYQSTLGHQADVVQPAEPCCPLAGRGQPLGDKRPKEADVPHIRPQEAPPEPSPGAHGDSSQEAMPPTSTVAPEEKTASSFLPSMPGPTKTKGGGEAVETQPAPGPLPPPEVRDIGERREPDRVQQQPQKPVVAAGTQNLRKFRQGFMKCLLEMEKVEASHRRALKARSLTAQKSPRTLTPVPTSSPSLPQTPASAPASGPSWARLSAPGPEPAPVGASVPTSTPCPVLLCPALDLGWRRMELSHHSSERTLSYAKARQEPEEQSLQKLYQNREKSEEQLTLKQEEAFRSYFEIFNGPGEVDAQSLKNILLLMGFSVTPAQVEDALMSADVNGDGHVDFKDFLAVMTDTRRFFCSVEQNALTDMAPHNPHTLLFEILPLLVEMLALPEAVLEEITNYYQKKLKAGTCKAQEMEAAIGRLRLQKQLPYNPQQEESSEVPERKVLSILSRLKQQNYAPNLQSPYAQVPCIPLCPRMDKKMVRRKPTNHYVQDQCTTPGLAPDIRSPFFQSRSQGNREHNSDSRKWPSSVPSRTH
What is the function of this protein?
Involved in the differentiation of haploid spermatids.
What are the official names of this protein?
Spermatogenesis-associated protein 21.
Protein: CABS1_BOVIN
Sequence: MAEDGLPKIYSHPPAESTKTTTEATIFFGADNTIPKSETTITSEGDHVTSVNDYMLENDFSTTTGNKLIPPKERQKSEDDVESHLEKEFATLMDIKNPMANESITENFLPVKTGNISSTDAISLIDFSTDIAKEDILLDTIDPGDKDVSLTSEVSGTPKESTAAIADTPILPNIMGKSDVSNYSSSVKFKVPADGNAHITDSSVPEAEITPTTERNLTTIPDITALTEEKITEIDLILPENDPNVVPKLTDSDEEKFITVFELTTTAERDKDNPEDALLTDEESTDEVSVWMERDMANEEESHSVLLTAVESRYDFVIPASVTMNLTEDLLTEEDLPENNRMESVTKNTDELSGTTPDLDAFSHKEDNFTTETGVFKLLKEEPDEFLI
What is the function of this protein?
Calcium-binding protein (By similarity).  Essential for maintaining the structural integrity of the sperm flagella (By similarity).
What are the official names of this protein?
Calcium-binding and spermatid-specific protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion inner membrane. Cell projection, cilium, flagellum. Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Mostly cytoplasmic, but associated with the mitochondrial inner membrane during the last steps of spermatid differentiation. Localizes to the principal piece of the sperm flagellum (By similarity).
Protein: TRMFO_BRUAB
Sequence: MSNNTDLSPVHVIGGGLAGSEAAWQIAQAGVPVVLHEMRPVRGTDAHKTEQLAELVCSNSFRSDDAETNAVGVLHAEMRLAGSLIMACADAHQVPAGGALAVDREGFSQAVTARLEAHPLITIEREEITGLPPTEWGTTIIATGPLTAPSLAEAIAAETDADALAFFDAIAPIIHFDSINMDVCWFQSRYDKVGPGGTGKDYINCPMDKEQYEAFVAALIEGDKTDFKEWEGTPYFDGCLPIEVMAERGPETLRHGPMKPMGLTNAHNPTVKPYAVVQLRQDNALGTLYNMVGFQTKLKYGSQTGIFKMIPGLENAEFARLGGLHRNTYLNSPVLLDNVLRLKSRQTLRFAGQVTGCEGYVESSAIGLLAGRFTAAEKLSQAAVPPPPTTAFGALLGHITGGHIVTNDEPGKRSFQPMNVNFGLFPPVDVPKPEGKRLRGKEKTIAKKRALSARALADCRNWLSLY
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_BUCAI
Sequence: MIFSNKNKIISRIRRSMKTRCKIKKLGAIRLVVHRTSRHMYAQIISSKEAKVLVFASTLERKINCSLKYTGNKEAAAKIGKIIAERALSKGISHVSFDRSGFKYHGRVQVLAESAREVGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: ATPD_YERP3
Sequence: MSEFVTVARPYAKAAFDFAVEHQAVERWQNMLAFTAQVTRNEQIAELLSGAVAPETMSTTFIAVCGDQLDEPAQNFIRVMAENGRLLVLPEVLQQFIQLRASLESTVDVEVSSARALNDEQLAKIAAAMEKRLSRKVKLNCKIDKSVMAGVVIRAGDMVIDGSVRGRLERLADVLQS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS19_STAA9
Sequence: MARSIKKGPFVDEHLMKKVEAQEGSEKKQVIKTWSRRSTIFPNFIGHTFAVYDGRKHVPVYVTEDMVGHKLGEFAPTRTFKGHVADDKKTRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: MURD_OLEA2
Sequence: MHTVIPHTHDTPAAAPVRSGAVAVVVGTGRSGTAAARLLHHLGASVRIVEKDESRVSAEFASLAARLGFDCRYGSHSAEQFAGADILVPSPGVPVASLLPYLDASRPPEIMAEIDLAARCVTSPVLAVTGTSGKTTTVSLCAAMLRAAGKRVFLGGNIGTPLSEYVLDVAAGEAPADVLVLEVSSFQLQTCTTLRPEVAVLINISANHLDYHADMQEYLDAKFRLFALQGPDDLAVLQSGMEELADRYALAARREFFDAVRRFPRTALLGSHNMANIEAAWLACRAFGVTQSQAAQAVEEFAPLEHRLEKVDEVAGVLFVNDSKSTTVDSMKAALESFDRPVLLLCGGKWKGGDLVSLIPVVRRHAKAVGLFGASREIFEHAWADVVPMSWDHDLQTAFRRMTAMAQPGDVVLMSPATSSYDLYSNYKERGGDFKRNVAAWKAERDD
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GDF8_BUBBU
Sequence: MQKLQISVYIYLFMLIVAGPVDLNENSEQKENVEKEGLCNACLWRENTTSSRLEAIKIQILSKLRLETAPNISKDAIRQLLPKAPPLLELIDQFDVQRDAGSDGSLEDDDYHARTDAVITMPTESDLLTQVEGKPKCCFFQFSSKIQYNKLVKAQLWIYLRPVKTPATVFVQILRLIKPMKDGTRYTGIRSLKLDMNPGTGIWQSIDVKTVLQNWLKQPESNLGIEIKALDENGHDLAVTFPEPGEDGLTPFLEVKVTDTPKRSRRDFGLDCDERSTESRCCRYPLTVDFEAFGWDWIIAPKRYKANYCSGECEFVFLQKYPHTHLVHQANPRGSAGPCCTPTKMSPINMLYFNGEGQIIYGKIPAMVVDRCGCS
What is the function of this protein?
Acts specifically as a negative regulator of skeletal muscle growth.
What are the official names of this protein?
Growth/differentiation factor 8, GDF-8, Myostatin.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: RAPZ_CITK8
Sequence: MVLMIVSGRSGSGKSVALRALEDMGFYCVDNLPVVLLPDLARTLADRQISAAVSIDVRNMPESPEIFEQAMNNLPDAFSPQLLFLDADRNTLIRRYSDTRRLHPLSSKNLSLESAIDQESDLLEPLRSRADLIVDTSEMSVHELAEMLRTRLLGKRERELTMVFESFGFKHGIPIDADYVFDVRFLPNPHWDPKLRPMTGLDKPVAAFLDRHTEVHNFIYQTRSYLELWLPMLETNNRSYLTVAIGCTGGKHRSVYIAEQLADYFRSRGKNVQSRHRTLEKRKT
What is the function of this protein?
Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ.  When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E.  Consequently, GlmZ is inactivated and unable to activate GlmS synthesis.  Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.
What are the official names of this protein?
RNase adapter protein RapZ.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family. RapZ subfamily.
Protein: RS21_WIGBR
Sequence: MPIIKIRENEPFDVALRRFKRSCEKAGILSEVRRREFYEKPTTERKRAKASAIKRHAKKMARENLKKTKFY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.