PharMolix/UniProtQA huggingface dataset:
Protein: FRDC_VIBVU
Sequence: MSNRKPYVREVKRTWWKDHPFYRFYMLREATVLPLILFTLFLTVGLGSLVKGPEAWQTWLNFMANPVVIAINIVALLGSLLHAHTFFSMMPQVMPIRLKGKPVDKKIIVLAQWAAVAFISLIVLIVV
What is the function of this protein?
Anchors the catalytic components of the fumarate reductase complex to the cell membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit C, Quinol-fumarate reductase subunit C, QFR subunit C.
What is the protein family that this protein belongs to?
Belongs to the FrdC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CCG6_NEUCR
Sequence: MKFSAAAVLAAAAGAHAWSNVTYTTEIVTAVTTYCPGPTEITHGGNTYTVTEATTLTISDCPCTVTKPIITTSSVICHSCTGYVNSTIPAPTSAGSVGTGSAPAVVTPTVSPSEVPTAGAGKAAALSGAGLVGVLGLAAILL
What are the official names of this protein?
Clock-controlled protein 6.
What is the protein family that this protein belongs to?
Belongs to the SED1 family.
Protein: CP6D3_MUSDO
Sequence: MLLFLLITLLSAIFIFAKRHYTQWQRLGLVSDEAVIPFGSLAKVFRKERPFGLVMYDLYEKFQEQVVGIYLFFKPALLIRDAELARQILTSDFNSFHDRGIYVDEKNDPMSANLFALEGQSWRTLRMKLTPSFSSGKLKGMFETVDDVGNKLLEYLNNQLKDGQTHVLDIKSILTTYAIDIIGSVIFGLEIDSFTNPDNEFRVLSDRSFDNESRSFLSKLQNLTNFVCPPIAKLLTRLGTKEPVVYRLRDIVKRTIEFREENNVVRKDLLHLLIQLRNTGKISDDNDNLWNKVESTATNLKAMSIDMIASNSFLFYIAGSETTASSTSFTIYELAMNPEALKKAQNEVDECLKKHGIKPDGRITYEAIQDMKYLDLCVKETTRKYPGLPFLNRQCTQDFKVPNSKFTIKKDTNVIISLLGLHRDAKYFPEPLAYKPERFADETKDYDAAAYMPFGEGPRHCIAQRMGVMNTKVALAKILANFNIEPMPHKEAEFQFNTAPVLVPVNGLRVGLSKRSFNRR
What is the function of this protein?
Metabolizes pyrethroid insecticides and other xenobiotics.
What are the official names of this protein?
Cytochrome P450 6d3, CYPVID3, Pyrethroid resistance cytochrome P450.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: SPEB_BACAN
Sequence: MRFDEAYSGKVFIKSHPSFEESEVVIYGMPMDWTVSYRPGSRFGPARIREVSIGLEEYSPYLDRELEEVKYFDAGDIPLPFGNAQRSLDMIEEYVSKLLDAGKFPLGLGGEHLVSWPIFKAMAKKYPDLAIIHMDAHTDLRESYEGEPLSHSTPIRKVCDLIGPENVYSFGIRSGMKEEFEWAKEVGMNLYKFDVLEPLKEVLPKLEGRPVYVTIDIDVLDPAHAPGTGTLEAGGITSKELLDSIVAIANSNINVVGADLVEVAPVYDHSDQTPVAASKFVREMLLGWVK
What is the function of this protein?
Catalyzes the formation of putrescine from agmatine.
What are the official names of this protein?
Agmatinase, Agmatine ureohydrolase, AUH.
What is the protein family that this protein belongs to?
Belongs to the arginase family. Agmatinase subfamily.
Protein: SCTN2_SALTY
Sequence: MKNELMQRLRLKYPPPDGYCRWGRIQDVSATLLNAWLPGVFMGELCCIKPGEELAEVVGINGSKALLSPFTSTIGLHCGQQVMALRRRHQVPVGEALLGRVIDGFGRPLDGRELPDVCWKDYDAMPPPAMVRQPITQPLMTGIRAIDSVATCGEGQRVGIFSAPGVGKSTLLAMLCNAPDADSNVLVLIGERGREVREFIDFTLSEETRKRCVIVVATSDRPALERVRALFVATTIAEFFRDNGKRVVLLADSLTRYARAAREIALAAGETAVSGEYPPGVFSALPRLLERTGMGEKGSITAFYTVLVEGDDMNEPLADEVRSLLDGHIVLSRRLAERGHYPAIDVLATLSRVFPVVTSHEHRQLAAILRRCLALYQEVELLIRIGEYQRGVDTDTDKAIDTYPDICTFLRQSKDEVCGPELLIEKLHQILTE
What is the function of this protein?
ATPase component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells (PubMed:24722491).  Acts as a molecular motor to provide the energy that is required for the export of proteins (By similarity).  Required for type III secretion apparatus (T3SA) formation, secretion of a subset of SPI-2 effectors and virulence (PubMed:24722491, PubMed:25035427).  May play a critical role in T3SS substrate recognition, disassembly of the effector/chaperone complex and unfolding of the effector in an ATP-dependent manner prior to secretion (Probable).  Releases the effector protein SseB from the T3SS-2 specific chaperone SsaE in an ATP-dependent manner (PubMed:24722491).
What are the official names of this protein?
SPI-2 type 3 secretion system ATPase, T3SS-2 ATPase.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Can associate with the membrane regardless of the presence of the other ATPase-associated components.
Protein: YD11A_YEAST
Sequence: MESQQLSNYPHISHGSACASVTSKEVHTNQDPLDVSASKIQEYDKASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWSFYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADSDMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELTFLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQYNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNMTVAELFLDIHAIYEEQQGSRNSKPNYRRNPSDEKNDSRSYTNTTKPKVIARNPQKTNNSKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLRPGTY
What is the function of this protein?
Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome.  The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules.  CA has also nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty1 RNA and initiation of reverse transcription (By similarity).
What are the official names of this protein?
Transposon Ty1-DR1 Gag polyprotein, Gag-p49, Transposon Ty1 protein A, TY1A, TYA, p58.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CARB_LEPIN
Sequence: MPRREDIRSVLILGSGPIVIGQACEFDYSGTQAAKALKEKGIRVILLNSNPATIMTDPDLADATYVEPMTVPVVQKILEKEKPDAILPTVGGQTALNLALACNSAGILEKYNVELIGAKVDAIKKAEDRELFKKAMEKIGVRVPASGLANNLKDAVEIKNKLGLPLIVRPAFTLGGTGGGIAYTEETFEEVVSKGLKASPISQVLLEESVLGWKEFELEVMRDLADNVVIICSIENIDPMGVHTGDSITVAPQQTLSDKEYQNLRDMSIAIIREIGVETGGSNIQFAVNPTNGDVIVIEMNPRVSRSSALASKATGFPIAKIAALLSIGYTLDEIKNDITRVTPASFEPSIDYVVTKVPRFAFEKFPGTDDTLGVQMKAVGEAMAIGRTFKESFQKALRSLEIDRYGFGSDGYFQELLYSRSLNNDQRKEWIDSHLKRPNDKRIFYVKLAFDEGYTVDQIHDLCKIDRWFLWQMEGLLKLEKEYSEKGNSILYKMKQVGFSNRQLSFLKNKKQILDLLDGNLRVDLKKTEIQNLLKLSEEEIEVELGSKKILPVYKRIDTCAGEFEAYTPYFYSSYDEEDESDVTNAKSVMILGGGPNRIGQGIEFDYCCCQASYALQDLGIESIMINSNPETVSTDYDTSDRLYFEPLTLEDVYRIYQNEKPEGVIIQFGGQTPLKLAKDLEKKGVKILGTSPDSIDRAEDRKRFVEVLEKLKLNSPESGIATSMEEAREIAHKIGYPVLVRPSYVLGGRAMLIINEEKELDRYMEKAEEISKDRPLLIDSFLEDAIEVDVDALCDGKEVFVTGIMEHIEEAGIHSGDSACVLPPQTLSKNMMDEIRKATVNLALELQVKGLINIQYAVKNEILYIIEVNPRASRTVPFVSKALGHPIVKYATRIMMGESLKSLPLPKEMEFSQVSVKEVVLPFNKFPGVDTILGPEMRSTGEVMGIASTAGEAFLKSQYMAGDELPSQGTVFVSINDKTKAELLSYIKDLSELGFNLIATSGTHKFLSDNGILSSKINKVYDGIFPTALDYIRENKIHLIINTPLSRVTRDDSFTIRQAAIRFKVPCLTTSNAAKALIKGMVEMKNKGFTIHSLQEIHAMPKIL
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: RS10_ECO8A
Sequence: MQNQRIRIRLKAFDHRLIDQATAEIVETAKRTGAQVRGPIPLPTRKERFTVLISPHVNKDARDQYEIRTHLRLVDIVEPTEKTVDALMRLDLAAGVDVQISLG
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: TIG_CHRSD
Sequence: MQVSVESTSQIERRVTVQVPAAEVDQAVATRLQETAKNVRLNGFRRGKIPLTVVRQRFGREVRNEVVGEMMRQHYVQAITQESLNPAGSPQVEPTVDEDGKDLEFVATLEVYPEFELNSIENTEIERPQAEVTEADVDQMIETLRTQHAEWEAVDRAAANGDQVTIDFEGYLGDEPFEGGAAEGHELELGSNSFIPGFEEQLVGAKAGDELEIKVTFPEDYQAAHLAGQEATFKVKVHKVAGKQLPEVDDEFIKRFGVEEGGVAAFRADVQKNMEHELSQAVTNRVKQQALEALQQANDIPVPQSLIQQETQGLKRQAAQQFGLGEDFDVSQLPDELFADQAKKRVQVGLLLAEVVKVNELDASDDEIKARVEELAQQYQQPEQVIEYYLKNDEMKNQIKSSVLEDKAVDKLLEQAQVKDVEMSYEQALQAAQQQEGAEEEAQEETSA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: ASSY_PARMW
Sequence: MGRANKVVLAYSGGVDTSVCIPYLKQEWGVEEVITFAADLGQGDELEPIRQKALDAGASQSLVGDLIQPFIEEFAFPAIRANALYEGRYPLSTALARPLIARRLVEVAREVGADAVAHGCTGKGNDQVRFDVAIAALAPDLKVLTPAREWGMSREETIAYGERCGIPAPVSKKSPYSIDLNLLGRSIEAGPLEDPMVAPPEEVFAMTSPMSDTPDAAEEIEIAFEAGNPVAINGQVLDPVAMIREANRLAGSHGIGRLDMIENRVVGIKSREIYETPGLLLLIQAHQELESLTLAADVLRSKRQLEMQWADLVYQGLWFGPLKDALDGFMDRTQQHVNGVVRLRLYKGNATVIGRGSTQSSLYVPAMASYGSEDAFDHRAAEGFIYVWGLPTRLWAASQRTSG
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YACG_SHESM
Sequence: MPLTVNCPICKTPVEWVPQSEFKPFCSERCKMIDLGDWASEKHAIPVKSEFDLDALDELGYDEESFFKE
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: PPN1_CRYNJ
Sequence: MRSPLLASLFALALSIASSEAAISSTEQVPLSGSVPQLDHSELQNVRINKKRPLKGRFLHITDIHPDPHYKTGSTFDSGCHRKPKKDGKSEGKKATENERGNEDLDDKEFDTLIKNEDLAGKWGTAVSDCDCPMSLVNITFDWLKEEWANEVDFVVWTGDNARHDIDRRIPRTPKEIFDSNRMIVDRMLDAFGRDMPIVPSIGNNDIYPHNVLAAGPSRITEEFLLIWKHFIPSEAAHVFERGAYFSVEVIPDRLAVISLNTLFWYDANTLVDGCRDHSNDPGALEMDWLEVQLNNFRQRGMQVWLTGHVPPHMNHYYDNCYLRYGDLALRYQDTIVGHLFGHMNVDHFFFIDVDELEATSELTSTSSNTTLSDLPLLHGPRLPRPGPGKYTAMGRSGARKLEEELRKDFGQMPGPGILKLKDYAVMNVAPSVIPTYYPGIRIFSYNISDEEDSFDQGHSYQGADELLDDEDEGDELEELELPSDNGFFGGLDERENEDIEILKGSGGHRHDVPKGDCSLPSNEDKPHCTFKRKPRHYSKRSPSRTNRALSPLGYTQFYLPSMMKQKKRPKWEVEYTTYKVKTLVPSSPENTTQPLPVPLHLLPRYDPSIFSKPKNKTEEKEVAKKTAKFYKAVKAVTPYRMKDLTIGSWVKLARMLVLEKKRWKKFAELMLVSTETD
What is the function of this protein?
Catalyzes the hydrolysis of inorganic polyphosphate (polyP) chains of many hundreds of phosphate residues into shorter lengths.
What are the official names of this protein?
Endopolyphosphatase.
What is the protein family that this protein belongs to?
Belongs to the endopolyphosphatase PPN1 family.
What are the subcellular locations of this protein?
Vacuole membrane; Single-pass type II membrane protein.
Protein: AROQ_DICTD
Sequence: MIKVLVLHGPNLNLLGVREPNIYGRVDFQTLNNLILQKAKEREIEVEIKQSNFEGQLIDWIQEYRDWADAIIINPGALTHYSYSLRDALLAFGKPVIEVHISNIYKREEFRHHSVIAPVALGQISGFGVNSYLLALEAIFLYFNK
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: DF128_ARATH
Sequence: MSKLTNVVIFIVFFLGMMAKETQGQHICHQILLNNNCDGATCTSLCDKQLQGTGQCYKTVDKRFICLCNYLCRT
What are the official names of this protein?
Putative defensin-like protein 128, Putative low-molecular-weight cysteine-rich protein 8, Protein LCR8.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: SRCRM_HUMAN
Sequence: MRAALWTLGLGPLLLNLWAVPIGGPGALRLAYRHSTCDGVVLVRHHGAWGYVCNQEWTLAEASVVCRQLGCGPAVGAPKYVPLPGEMAQPWLHNVSCRGNESSLWECSLGSWCQSPCPHAWVVVALCSNGTFRELRLVKGRSPCAGLPEIRNVNGVDRLCVLHVEEAMVFCRELGCGPVLQAPRRDVGVVRKYLACRGTEPTIRSCRLDNNFRSGCDLRLDAEVVCSGHTEARLVGGEHPCAGRLEVTWGTVCDAALDLATAHVVCRELQCGAVVSTPEGARFGRGSGPVWTEAFRCAGNESLLFHCPRGRGSQCGHGHDAGLRCSEFRMVNGSSSCEGRVEFQVQGSWAPLCATHWDIADATVLCHQLNCGNAVAAPGGGHFGDGDAAIWPDAFHCEGTESYLWNCPVSTLGAPACAPGNTASAVCSGLAHALRLREGQSRCDGRVEVSLDGVWGRVLDDAWDLRGAGVVCRQLGCRGAQQAYDAPAPSRGSVQVALSRVRCLGTETRLTQCNVSATLQEPAGTSRDAGVVCSGEVGTASPMARRHGIPGALTLSLHREPQGAAGRGAGALHGGAWGTVCDDAWDLRDAHVVCRQLGCGRALSALGAAHFGAGAGRIWLDELGCQGHESALWQCPSAGWGRHDWRHKEDAGVFCSESVALRLRGGTCCCAGWLDVFYNGTWGAMCSNALKDLSLSIICKQLGCGVWGVGLAGEQALPLCGHRDRLGGQHRVPQAAQLHSVAMPFPPMAPALLRPSRAGLSEDRPQAAGEPLNCSSWLGCPEEGALRVRGGEDRCSGRVELWHAGSWGTVCDDGWDLADAEVVCRQLGCGRAVAALGAAAFGPGSGPVWLDEVGCRGSEASLWGCPAERWGRGDRAHEEDAGVRCWEPGPGPPLPAAPFRTFWVVSVVLGSLLGLLLLGLMAFLILPRVTQAMQRGLGRSEVSPGEAIYDVIGEMPPAGLYEEIMEAEAVLQDEEDGSVVKVDTEAAVSGEVSNLLEGQSIRAEGGHSRPVSQGYDEAAFPLEEMTL
What is the function of this protein?
May play a role in the immune system, perhaps as a co-receptor on alphabeta and gammadelta T-cells.
What are the official names of this protein?
Scavenger receptor cysteine-rich domain-containing protein SCART1, Scavenger receptor family member expressed on T cells 1.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MIAB_AZOSB
Sequence: MKKLYIRTFGCQMNEYDSEKMADVLGAGEGIAKTDNPEEADVILFNTCSVREKAQEKVFHDLGRVKHLKQLKPDLIIGVGGCVASQEGDAIVARAPYVDVVFGPQTLHRLPALIAARKQSGRSQVDISFPEIEKFDAMPPARVEGASAFVSIMEGCSKYCTFCVVPYTRGEEISRPLEDVLAEIAGLAEQGVKEVTLLGQNVNAWRGEIVRDAGEEGDFAFLLECVAEIPGIERIRYTTSHPREMTQRLFDAYVKIPKLVSQLHLPVQSGSDRILAAMKRGYSVLEFKSIVRKLRAARPDLSLSSDFIVGFPGETEEDFEKTMKLIDEVGFDGSFSFVYSARPGTPAADLEDPVPQETKLAWLARLQKRIDEQAQAVSQSMVGSAQRILVEGVSRKSAEELMGRTDNNRVVNFPAPSPHRDRLVGQFIEVRITSALPHSLRGEILTRES
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KYNU_XANCB
Sequence: MMTDPLSRSHAAALDAADPLRALRDAFVFPQHGGQDQTYFVGNSLGLQPRQARAMVSEVLDQWGALAVEGHFTGPTQWLTYHQLVRDGLARVVGAQPDEVVAMNTLTVNLHLMMASFYRPSAERAAILIEAGAFPSDRHAVESQLRLHGLDPDTHLIEVEPDAADGTLSMDAIAAAIAQHGPRLALVLWPGIQYRTGQAFALGEIARLARAQGAAVGFDLAHAVGNIPLSLHDDGVDFAVWCHYKYLNAGPGAVGGCFVHARHAHSNLPRMAGWWGHEQPTRFRMEPQFVPSPGAEGWQLSNPPVLALAPLRASLELFDQAGMPALRAKSEQLTGHLEQLIHTRVPQVLQIVTPADPAQRGCQLSLRVAGGRTQGRALFEYLQSVGVLGDWREPDVIRIAPVPLYNRFCDLHQLVEHVETWAAA
What is the function of this protein?
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
What are the official names of this protein?
Kynureninase, L-kynurenine hydrolase.
What is the protein family that this protein belongs to?
Belongs to the kynureninase family.
Protein: CAH3_BOVIN
Sequence: MAKEWGYADHNGPDHWHELFPNAKGENQSPIELNTKEISHDPSLKPWTASYDPGSAKTILNNGKTCRVVFDDTYDRSMLRGGPLAAPYRLRQFHLHWGSSDDHGSEHSVDGVKYAAELHLVHWNSKYNSYATALKHADGIAVVGVFLKIGREKGEFQLLLDALDKIKTKGKEAPFNNFNPSCLFPACRDYWTYHGSFTTPPCEECIVWLLLKEPITVSSDQIAKLRTLYSSAENEPPVPLVRNWRPPQPIKGRIVKASFK
What is the function of this protein?
Reversible hydration of carbon dioxide.
What are the official names of this protein?
Carbonic anhydrase 3, Carbonate dehydratase III, Carbonic anhydrase III, CA-III.
What is the protein family that this protein belongs to?
Belongs to the alpha-carbonic anhydrase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_ECODH
Sequence: MIQEQTMLNVADNSGARRVMCIKVLGGSHRRYAGVGDIIKITIKEAIPRGKVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVLLNNNSEQPIGTRIFGPVTRELRSEKFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: MCTS1_CHICK
Sequence: MFKKFDEKENVSNCIQLKTSVIKGIKNQLIDQFPVIEPWLNQIMPKKDPVKIVRCHEHIEILTVNGELLFFRQREGIFYPTLRLLHKYPFILPHQQVDKGAIKFVLSGANIMCPGLTSPGAKLYPAAVDTVVAIMAEGKQHALCVGVMKMSADDIEKVNKGIGIENIHYLNDGLWHMKTYK
What is the function of this protein?
Plays a role as translation enhancer and involved in cell cycle regulation.
What are the official names of this protein?
Malignant T-cell-amplified sequence 1, MCT-1.
What is the protein family that this protein belongs to?
Belongs to the MCTS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TETR_MYCA9
Sequence: MVARGETRSAALLAVALQVLIRDGYDRFSMDSVAALAHASKTTIYRRWSNKAELIKAALDAHDASFNDEVFDTGGLRTDLIATMGMLRRKAQALPPTLYPDLIRAMEHDETLSDAIRRHLADPGLSPFDAPLSRAVGRGEAGVDVDRQLIHDVAEAMLTHRLTLGGPLDDAFIGRLVDDVLLVLIRPGAR
What is the function of this protein?
Binds to its own palindromic promoter and represses transcription of its operon; addition of tetracycline or doxycycline (but not tigecycline) interferes with DNA binding.  Addition of TetX to the DNA-TetR-antibiotic complex restores DNA binding.
What are the official names of this protein?
DNA-binding transcriptional repressor TetR, MabTetRx.
Protein: YCIB_YERPB
Sequence: MKQLLDFLPLVVFFIFYKMYDIFVASGALIVATLVALAFTWLKYRKVEKMTLVTAAMVLVFGTLTLAFHSDLFIKWKVTVLYVLFALALLVSQWVMKKPLIQRMLGKELTLPDKVWSTLNLSWAIFFLVCGLLNIYVAFWLPQDIWVNFKVFGLTALTLIFTLISGVYIYRHMPEEQKKS
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RLMG_ECOLC
Sequence: MSHLDNGFRSLTLQRFPATDDVNPLQAWEAADEYLLQQLDDTEIRGPVLILNDAFGALSCALAEHKPYSIGDSYISELATRENLRLNGIDESSVKFLDSTADYPQQPGVVLIKVPKTLALLEQQLRALRKVVTSDTRIIAGAKARDIHTSTLELFEKVLGPTTTTLAWKKARLINCTFNEPQLADAPQTVSWKLEGTDWTIHNHANVFSRTGLDIGARFFMQHLPENLEGEIVDLGCGNGVIGLTLLDKNPQAKVVFVDESPMAVASSRLNVETNMPEALDRCEFMINNALSGVEPFRFNAVLCNPPFHQQHALTDNVAWEMFHHARRCLKINGELYIVANRHLDYFHKLKKIFGNCTTIATNNKFVVLKAVKLGRRR
What is the function of this protein?
Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase G, 23S rRNA m2G1835 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RlmG.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30E_PYRHO
Sequence: MDLAFELKKALETGKVILGSNETIRLAKTGGAKLIIVARNAPKEIKDDIYYYAKLSDIPVYEFEGTSVELGTLLGKPFVVASLAIVDPGESRILALVKR
What are the official names of this protein?
50S ribosomal protein L30e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL30 family.
Protein: CLCA_VIBVU
Sequence: MTKRERIIQSVLVKVPKDAINQFLSHGSTPISVLFLAALVGVLAGLVGTYFEIAVHFVSETRTEWLKSEIGHLLPLWLAAILISAALAFVGYFLVHRFAPEAAGSGIPEIEGAMDNIRPVRWWRVIPVKFFGGMGALGSGMVLGREGPTVQMGGAVGRMVTDIFRVKDDDTRHSLLASGAAGGLAAAFNAPLAGIMFVVEEMRPQFRYSLISIRAVIISAVMANIVFRAINGQDAVITMPQYQPPELKALWLFLLLGGLFGVFGVLFNKLVTVAQDAFVALHKNDRKRYLITGTCLGGIFGLLLLYVPELTGGGIHLIPDVTNGNYSVSLLVMLFVGRVLTTLICFGSGAPGGIFAPMLALGTLFGYAFGATAKILLPDLPIEPGMFAIAGMGALFAATVRAPITGILLVIEMTNNYYLILPLIITSLGAVICAQICGGKPIYSQLLHRTIKNDKLRQQDLPEQQNS
What is the function of this protein?
Proton-coupled chloride transporter.  Functions as antiport system and exchanges two chloride ions for 1 proton.  Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.
What are the official names of this protein?
H(+)/Cl(-) exchange transporter ClcA.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClcA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS13_XYLFT
Sequence: MARIAGVNLAIQKHVWIGLQSIYGIGRTRSRKVCDAANVAIYTKIRDLSESEIERLRVEVGKYVIEGDLRREVGMAIKRLMDLNCYRGLRHRRCLPLRGQRTRTNARTRKGPRKAIKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: TDH_SHIBS
Sequence: MKALSKLKAEEGIWMTDVPVPELGHNDLLIKIRKTAICGTDVHIYNWDEWSQKTIPVPMVVGHEYVGEVVGIGQEVKGFKIGDRVSGEGHITCGHCRNCRGGRTHLCRNTIGVGVNRPGCFAEYLVIPAFNAFKIPDNISDDLASIFDPFGNAVHTALSFDLVGEDVLVSGAGPIGIMAAAVAKHVGARNVVITDVNEYRLELARKMGITRAVNVAKENLNDVMAELGMTEGFDVGLEMSGAPPAFRTMLDTMNHGGRIAMLGIPPSDMSIDWTKVIFKGLFIKGIYGREMFETWYKMAALIQSGLDLSPIITHRFSIDDFQKGFDAMRSGQSGKVILSWD
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRG1_MOUSE
Sequence: MSERKEGRGKGKGKKKDRGSRGKPAPAEGDPSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRRNKPQNVKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNDLTTGMSASTERPYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLIKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKHLGIEFMEAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRQKLHDRLRQSLRSERNNMVNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREVETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESIISESHSVIMMSSVENSRHSSPAGGPRGRLHGLGGPRECNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSVAVSPFVEEERPLLLVTPPRLREKKYDHHPQQLNSFHHNPAHQSTSLPPSPLRIVEDEEYETTQEYEPIQEPIKKVTNSRRAKRTKPNGHIANRLEMDSNPSSVSSNSESETEDERVGEDTPFLGIQNPLAASLEVAPAFRLAESRTNPAGRFSTQEELQARLSSVIANQDPIAV
What is the function of this protein?
Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors.  Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors.  Perform diverse functions such as inducing growth and differentiation of epithelial, glial, neuronal, and skeletal muscle cells; inducing expression of acetylcholine receptor in synaptic vesicles during the formation of the neuromuscular junction; stimulating lobuloalveolar budding and milk production in the mammary gland and inducing differentiation of mammary tumor cells; stimulating Schwann cell proliferation; implication in the development of the myocardium such as trabeculation of the developing heart.  Binds to ERBB4 and ERBB3.  Acts as a ligand for integrins and binds (via EGF domain) to integrins ITGAV:ITGB3 or ITGA6:ITGB4.  Its binding to integrins and subsequent ternary complex formation with integrins and ERRB3 are essential for NRG1-ERBB signaling (By similarity).  Induces the phosphorylation and activation of MAPK3/ERK1, MAPK1/ERK2 and AKT1, and ligand-dependent ERBB4 endocytosis is essential for the NRG1-mediated activation of these kinases in neurons (By similarity).
What are the official names of this protein?
Pro-neuregulin-1, membrane-bound isoform, Pro-NRG1.
What is the protein family that this protein belongs to?
Belongs to the neuregulin family.