PharMolix/UniProtQA huggingface dataset:
Protein: RNB_VIBVU
Sequence: MFQDNPLLAQLKQQIQENLPKKEGTIKATEKGFGFLEVDSKTSFFIPPAYMKKCMHGDKVIAIIRTENEREVAEPQELVEQMLNRFIGRVKMFKGKLNVVPDHPQLKKMSLKAKTKKGLNPQEFAEGDWVVGHLIRHPLKDDNGFFVEISEKITDADDKIAPWWVTLAENDLPNSEPAGIDDWQIKDDADLERIDMTHIPFVTIDGESTKDMDDALYAKKNDAGDFELTIAIADPTAYITPDDEMDKVARERGFTIYLPGRNIPMLPRDLADELCSLIEGEIRPALCCTVTVSKDGVIGDDIQFFAANIKSHARLAYDNVSDWLETGSCEKWQPSEEIAAIVRDLYEFSQARAEWREKNAVVFPDRPDYRFELSEDNDVVAIHADMRRSANRLVEESMITANICAGKTLQGHFGTGVFNCHAGFKPEKIADVVELVNPEGTLEFTAESIATREGFAALRRWLSKQETTYLDNRIRKFQTYSEVSNQPLPHYAMGLDIYATWTSPIRKYGDMINHRMLKALILNKEPVQKPDDSVGEELALHRKHHKIAERNVADWLYARTLADAPENQTLFTGEIFDINRAGMRIRLLENGAAAFIPGSLIIDNKERIECNGDLGTVSIDKEVVYKLGDVLEVVLADVNQENRSLVAKPTQVFAELPVVEETQN
What is the function of this protein?
Involved in mRNA degradation.  Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.
What are the official names of this protein?
Exoribonuclease 2, Exoribonuclease II, RNase II, Ribonuclease II.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family. RNase II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHPS_STRP8
Sequence: MKIGRFVIEGNAAIMGILNVTPDSFSDGGSYTTVQKALDHVEQMIADGAKIIDVGGESTRPGCQFVSATDEIDRVVPVIKAIKENYDILISIDTYKTETARAALEAGADILNDVWAGLYDGQMFALAAEYDAPIILMHNQDEEVYQEVTQDVCDFLGNRAQAALDAGVPKNNIWIDPGFGFAKSVQQNTELLKGLDRVCQLGYPVLFGISRKRVVDALLGGNTKAKERDGATAALSAYALGKGCQIVRVHDVKANQDIVAVLSQLM
What is the function of this protein?
Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
What are the official names of this protein?
Dihydropteroate synthase, DHPS, Dihydropteroate pyrophosphorylase.
What is the protein family that this protein belongs to?
Belongs to the DHPS family.
Protein: COL71_CAEEL
Sequence: MRNAGGDKPFSTPVLLREMGLKTHVDDDPKTKAYRLIGYAAVTFSTVSVICFCVTMPVVFTYVQSVKRQMSHEMATCNVNARQIFDDVAALRAGFPFAQAGNRTARQAGYDVHPSKPTPVGYSGGDAAAAEVKGNSPAAAYEDKPFVAVGVEEGPHTATTGSDSEGTCHDCCLPGPPGPPGPPGRPGPNGKAGANGLNGNPGRPPEAPCEPVTPPPCPPCPAGPKGAPGQAGYPGADGQPGSQGDNGEKGSDGAAGEKGRPGPLGKIGEPGATGETGENAENSEPTPGPQGPPGAIGPVGSRGTPGHPGEDGEAGAPGAPGENGTDGENGEDGVPGVPGHDGKAGRAGERGICPKYCAKDGGIFFEDGTRR
What is the function of this protein?
Probable cuticular collagen-like protein (Probable).  Nematode cuticles are composed largely of collagen-like proteins (Probable).  The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment (Probable).  Acts downstream of the Wnt signaling pathway, perhaps in the formation of the adult cuticle (PubMed:24569038).
What are the official names of this protein?
Cuticle collagen 71.
What is the protein family that this protein belongs to?
Belongs to the cuticular collagen family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Nucleus.
Protein: ESXF_MYCTU
Sequence: MGADDTLRVEPAVMQGFAASLDGAAEHLAVQLAELDAQVGQMLGGWRGASGSAYGSAWELWHRGAGEVQLGLSMLAAAIAHAGAGYQHNETASAQVLREVGGG
What are the official names of this protein?
ESAT-6-like protein EsxF.
What is the protein family that this protein belongs to?
Belongs to the WXG100 family. CFP-10 subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Probably secreted via the ESX / type VII secretion system (T7SS).
Protein: COX2_DEKBR
Sequence: MYMLNNMLNDVPTPWGMFFQDSATPNMEGMMELHNNVMFYLCMMLGFVSYMLYNMLTTYNHSVLPYKYLYHGQFIEIVWTTFPAMILLIIAFPSFILLYICDEVIAPAMTIKAMGLQWYWKYEYSDFIDDKGETIEFESYMIPEDLLEEGQLRQLDVDSPIVCPVDTHMRFIVTAADVIHDFAMPSLGIKIDAVPGRLNQTSALIQREGVYYGQCSELCGVMHSSMPIKIEAVSLGEFLAWIDEQ
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TRMB_UREU1
Sequence: MRLRNNANAPLYLKSQEQYIVNDQQLLKNDLAKVFKNPHLPLHIEIGMGKGDFIVENALHNPQINYLGIEKFPTVIVKAHKKALKHKLDNLAMICFDANAILDLLNSKSIDKIYLNFSDPWPKKRHAKKRLTNPYFLEKFAALLKDDGLIEFKTDNESLFHYTIYDVLLNDLTKYEILFLTYNLYALVNNVELLKNIPTEYEKKFVMQGQRIKKVSFRFLKKND
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: CRCB_THET8
Sequence: MERYLLVALGGALGSLLRYGLGALVQGSLGAGFPWSTLFVNALGSFLIGLTLRLSLEGALSGEARLFLAVGVLGGFTTFSSLSYETLALLQGGEVGKALLYAFGSLFLGLFLAFLGYRLGGALVG
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y4228_XANC8
Sequence: MTETLPTPVLDTAQARVLGCLIEKEATTPDAYPLTVNAAQVAANQKTAREPVLTLQTGKVHHALRQLETLGLVRQQFSSRAERYEHRLGSALDLTRQQVAVIGLLLLRGPQTLGELFARSERLARFNDSDDVRHHLERLIQRGLAVQLPRASGQREDRYAHLLSGELDLDALQAAAARAAPSARSGADSSELEARVLSLETTVAELQDALSALQARLDAAGA
What are the official names of this protein?
UPF0502 protein XC_4228.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: CCL27_HUMAN
Sequence: MKGPPTFCSLLLLSLLLSPDPTAAFLLPPSTACCTQLYRKPLSDKLLRKVIQVELQEADGDCHLQAFVLHLAQRSICIHPQNPSLSQWFEHQERKLHGTLPKLNFGMLRKMG
What is the function of this protein?
Chemotactic factor that attracts skin-associated memory T-lymphocytes.  May play a role in mediating homing of lymphocytes to cutaneous sites.  Binds to CCR10.
What are the official names of this protein?
C-C motif chemokine 27, CC chemokine ILC, Cutaneous T-cell-attracting chemokine, CTACK, ESkine, IL-11 R-alpha-locus chemokine, Skinkine, Small-inducible cytokine A27.
What is the protein family that this protein belongs to?
Belongs to the intercrine beta (chemokine CC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: ANMK_ECOLI
Sequence: MKSGRFIGVMSGTSLDGVDVVLATIDEHRVAQLASLSWPIPVSLKQAVLDICQGQQLTLSQFGQLDTQLGQLFADAVNALLKEQNLQARDIVAIGCHGQTVWHEPTGVAPHTLQIGDNNQIVARTGITVVGDFRRRDIALGGQGAPLVPAFHHALLAHPTERRMVLNIGGIANLSLLIPGQPVGGYDTGPGNMLMDAWIWRQAGKPYDKDAEWARAGKVILPLLQNMLSDPYFSQPAPKSTGREYFNYGWLERHLRHFPGVDPRDVQATLAELTAVTISEQVLLSGGCERLMVCGGGSRNPLLMARLAALLPGTEVTTTDAVGISGDDMEALAFAWLAWRTLAGLPGNLPSVTGASQETVLGAIFPANP
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: METK_DEHMC
Sequence: MSQTFGNSSKYLFTSESVTEGHPDKICDQISDAVLDAIIAKDPTAHVACETAVTNGLVVVMGEITTSCYVEIPELVRGVIKDIGYIKPEYGFDDRTCGVLTSINRQSPDIALGVNKSQEAKSGQVDELDLTGAGDQGMMFGYACTETPEYMPLPISLAHRLSKRLAEVRKNGTLPYLRPDGKSQVTVEYHNGKAKRISSVVIGAQHDPDITTEKIQADIIREVIKPIIPTNLLDEKTEYYVNATGRFVVGGPVSDTGFTGRKILVDTYGGFARHGGGAFSGKDPTKVDRSACYMARYIAKNLVAAGLADRLEIQVAYVIGVAHPLSVSIETFNTARMNHEDILSIIQKHFDLRPEAIIRNLGLRRPIYRQTAAYGHLGRPELDLPWERLDKVDAIKATIESLSVSK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXR_NOCFA
Sequence: MRPPSRCPGMRHNDGVSDIVRVLLLGSTGSIGTQALEVIAANPDKFEVVGLAARGGNPALLAEQMAATGTRNVAVADPAAGAALDIKLAGPHAVTELVRRTEADVVLNALVGSLGLEPTLATLTAGTRLALANKESLVAGGSLVTRAAAPGQIVPVDSEHSALAQCLRGGRADEVDRLVLTASGGPFRGWTAQMLESVNPEAAKAHPTWSMGLMNTLNSASLVNKGLELIETHLLFGIPYDRIDVTVHPQSIVHSMVTFVDGSTLAQASPPDMKLPIALALGWPDRVPGAAAACDFSTASTWTFEPVDTEVFPAVELARQAGQAGGSVTAVYNAANEVAVQAFLDGRIRFPEIVRTVARAVEAADRWRAEPETVEDVLAADRWARGRAAELVGA
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: RNPH_SYNE7
Sequence: MAWIRPDGRRPDQLRAIAFQRRFTQFPAGSVLAQFGQTQVLCTVTIQAGVPRWLTGQGQGWLTAEYRMLPGATPDRQSREWLKLSGRTQEIQRLIGRSLRAAIDLKKLGERTLLIDADVLQADAGTRTTAINGSWVALQDAIAQLIAQGELTESPIQRSIAAVSVALIGGEAFLDPDYPEDVQADVDCNVVMGDRGELIEIQGTAEANPFSRTQLNHILDLAEQGIAQIQAAQLEALR
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: GFA2_ARATH
Sequence: MVPSNGAKVLRLLSRRCLSSSLIQDLANQKLRGVCIGSYRRLNTSVGNHANVIGDYASKSGHDRKWINFGGFNTNFGSTRSFHGTGSSFMSAKDYYSVLGVSKNAQEGEIKKAYYGLAKKLHPDMNKDDPEAETKFQEVSKAYEILKDKEKRDLYDQVGHEAFEQNASGGFPNDQGFGGGGGGGFNPFDIFGSFNGDIFNMYRQDIGGQDVKVLLDLSFMEAVQGCSKTVTFQTEMACNTCGGQGVPPGTKREKCKACNGSGMTSLRRGMLSIQTTCQKCGGAGQTFSSICKSCRGARVVRGQKSVKVTIDPGVDNSDTLKVARVGGADPEGDQPGDLYVTLKVREDPVFRREGSDIHVDAVLSVTQAILGGTIQVPTLTGDVVVKVRPGTQPGHKVVLRNKGIRARKSTKFGDQYVHFNVSIPANITQRQRELLEEFSKAEQGEYEQRTATGSSQ
What is the function of this protein?
Chaperone that may play a role in mitochondrial protein folding.  Involved in female gametophyte development.  Required for cell death of the synergid cells during fertilization process, and fusion of the polar nuclei during megagametogenesis.
What are the official names of this protein?
Chaperone protein dnaJ GFA2, mitochondrial, Chaperone protein dnaJ A30, AtDjA30, Gametophytic factor 2.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SECG_ECOLI
Sequence: MYEALLVVFLIVAIGLVGLIMLQQGKGADMGASFGAGASATLFGSSGSGNFMTRMTALLATLFFIISLVLGNINSNKTNKGSEWENLSAPAKTEQTQPAAPAKPTSDIPN
What is the function of this protein?
Subunit of the protein translocation channel SecYEG.  Overexpression of some hybrid proteins has been thought to jam the protein secretion apparatus resulting in cell death; while this may be true it also results in FtsH-mediated degradation of SecY.  Treatment with antibiotics that block translation elongation such as chloramphenicol also leads to degradation of SecY and SecE but not SecG.
What are the official names of this protein?
Protein-export membrane protein SecG, P12, Preprotein translocase band 1 subunit.
What is the protein family that this protein belongs to?
Belongs to the SecG family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSAI_OLTVI
Sequence: MTAAYLPSILVPLVGLVFPAIAMASLFLYIEEQQIS
What is the function of this protein?
May help in the organization of the PsaL subunit.
What are the official names of this protein?
Photosystem I reaction center subunit VIII, PSI-I.
What is the protein family that this protein belongs to?
Belongs to the PsaI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RL31_AERPE
Sequence: MPSEGTWVYVVNLRRVYWGRRTRRAIRAVRMVREFVRRHTKADEVVIDNELNNYIWSRSREKPPARVKIIVSIREEEPEEGGERIRKAVVRLAGRKLRPGRYKG
What are the official names of this protein?
50S ribosomal protein L31e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL31 family.
Protein: OMT3_SORBI
Sequence: MVLISEDSRELLQAHVELWNQTYSFMKSVALAVALDLHIADAIHRRGGAATLSQILGEIGVRPCKLPGLHRIMRVLTVSGTFTIVQPSAETMSSESDGREPVYKLTTASSLLVSSESSATASLSPMLNHVLSPFRDSPLSMGLTAWFRHDEDEQAPGMCPFTLMYGTTLWEVCRRDDAINALFNNAMAADSNFLMQILLKEFSEVFLGIDSLVDVAGGVGGATMAIAAAFPCLKCTVLDLPHVVAKAPSSSIGNVQFVGGDMFESIPPANVVLLKWILHDWSNDECIKILKNCKQAIPSRDAGGKIIIIDVVVGSDSSDTKLLETQVIYDLHLMKIGGVERDEQEWKKIFLEAGFKDYKIMPILGLRSIIELYP
What is the function of this protein?
O-methyltransferase involved in the biosynthetic pathway of the phytotoxin sorgoleone, a potent broad-spectrum inhibitor active against many agronomically important monocot and dicot weed species.  Substrate specificity for alkylresorcinols.  Strong preference for a five carbons alkyl side chain.
What are the official names of this protein?
5-pentadecatrienyl resorcinol O-methyltransferase, O-methyltransferase 3, SbOMT3.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. COMT subfamily.
Protein: LEU1_ANOFW
Sequence: MRKINIFDTTLRDGEQSAGVNLNLHEKLEIARQLERLGVDIIEAGFPAASKGDFQAVQAIAQTVRNCSVTGLSRSVQSDIDAAWEALKDGAEPRLHVFIATSPIHMQYKLRMTPEQVVETAVESVRYAKKYFPIVQWSAEDACRSDLPFLATIVEKVIEAGANVINIPDTVGYITPKQYGDIFSFLKKNVRNIEKISLSAHCHDDLGMAVANSLAAIEAGATQIEGTINGIGERAGNAAIEEVAVALYIRKDYYQAETRLNLQEIKRTSSLVSKLTGMIVPANKAIVGKNAFAHESGIHQDGVLKEKTTYEIISPQLVGVQSNSMVLGKHSGRHAFRTRIQELGYSLTEEEVNRLFVRFKDLADKKKDITDDDLIALILDEKLDTYKNFYQLCSIQVQYGTNQIPTAVVVLKDGEGNDIQEAATGAGSVEALYNALEKALQLPVTLLDYRIESVGSGRDALAQVYVKVSLDRKEASGRGTAQDVLEASAKAYIHAVNRMFVIEKMKEEQALAAQ
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: TUSA_ECOLU
Sequence: MTDLFSSPDHTLDALGLRCPEPVMMVRKTVRNMQPGETLLIIADDPATTRDIPGFCTFMEHELVAKETDELPYRYLIRKSG
What is the function of this protein?
Sulfur carrier protein involved in sulfur trafficking in the cell.  Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA.  Interacts with IscS and stimulates its cysteine desulfurase activity.  Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation.  Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.
What are the official names of this protein?
Sulfur carrier protein TusA, Sulfur mediator TusA, Sulfur transfer protein TusA, tRNA 2-thiouridine synthesizing protein A.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSM_ECOLI
Sequence: MSTLEQTIGNTPLVKLQRMGPDNGSEVWLKLEGNNPAGSVKDRAALSMIVEAEKRGEIKPGDVLIEATSGNTGIALAMIAALKGYRMKLLMPDNMSQERRAAMRAYGAELILVTKEQGMEGARDLALEMANRGEGKLLDQFNNPDNPYAHYTTTGPEIWQQTGGRITHFVSSMGTTGTITGVSRFMREQSKPVTIVGLQPEEGSSIPGIRRWPTEYLPGIFNASLVDEVLDIHQRDAENTMRELAVREGIFCGVSSGGAVAGALRVAKANPDAVVVAIICDRGDRYLSTGVFGEEHFSQGAGI
What is the function of this protein?
Two cysteine synthase enzymes are found.  Both catalyze the same reaction.  Cysteine synthase B can also use thiosulfate in place of sulfide to give cysteine thiosulfonate as a product.
What are the official names of this protein?
Cysteine synthase B, CSase B, O-acetylserine (thiol)-lyase B, OAS-TL B, O-acetylserine sulfhydrylase B.
What is the protein family that this protein belongs to?
Belongs to the cysteine synthase/cystathionine beta-synthase family.
Protein: JHD1_CAEEL
Sequence: MDPEALNLEFYDKNGLDNPIHFRCDPKRIGMTLPSPDFSVDDVLELVGGNRMIEVVQVQNQGSVKMSLQEFINFYKTPQEKREVLYNVLSLEFSQTPLEDLVKSPELVRQIDWVGNQWPDALRQRWISFNGRDKKFYNPHHTFPKVQNYCLMSVANCYTDFHIDFSGTSVWYHVLKGRKVFWLIPPTETNFFIYQEFIKTVNDNAFFGKSVEKCHVAILEPGDTMLIPSGWIHAVYTPDDSLVFGGNFLHSQSCKTQLRVYQVENKLNITRKFRLPYNEELIFYVIADYVKQWTGREYVRPLRIEDAKYDYVGDKWKTAGGHHKKIEYSDYETGVELTNDMIKGDEESTKDEVKVIAMHAENSLFGYPMVSKATFSADTGLEEEADEDEVKYQETKEEMDARRDAEIDELANSNSLIFYKNRTHDFVRNKCVPDHKLPIGHEPPIYFNDDEISRISPRLLDELETLGTYIRRKARVEVAEGICQPASLINTFQTVLKKRRSELTGKKFEFNQIMPRRYTRSTMETGEYDFQPTQEVPQESARRSTRFKVDNFPDELLESEVTDKPIILPQQPSSGPLEYLPAPKDEIKEDINGFEEEFEEEYEGIGQRDDQEEEEYDAEEPEDQEEEEEDEYQAEEYTPTPVTRRSSSRRSGAKNDESEEVSVKKDKKEKMEKVEKDEKRRNSKSKKDKISKEKKKKERERIELESQLDAELRAAHGGGSSKSKKKKPEKPAFVGGLPTSSIQIDPVVSNPYNYDPRMEMMKLGTGQLKSAYRKTKNNVELHIEKNLYKIEPKRGSEEGSQSREQSMEPEHSTPVFTTFDDINEANNDHYDGQKPPTKRAKYEAISVDTYETPSSSRNKEHKEYRPSPNAAPTPSPSHHQKPKLSSPAMVSSTNEYQLRKHMSSERRSSDAGSAMKKGVYMPAMSRQDKMIAEGASAPSSRHSSISSERRPSFIPDFNSSRNSSIDTPYTPTTVTPSRSSWLPNTSSINRHSIEDDSPIDVVNDSLSPINIASSPTYPTAITPPPVTLSDLKKDMSNGRKSHSQHHDDGHKHKIPSKEAIAELKLLVGKLKAINDS
What is the function of this protein?
Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code (By similarity).  Has a role in regulating lifespan.
What are the official names of this protein?
JmjC domain-containing histone demethylation protein 1, [Histone-H3]-lysine-36 demethylase 1.
What is the protein family that this protein belongs to?
Belongs to the JHDM1 histone demethylase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYNS_FUSV7
Sequence: MANEGRIATLDSTVADRLPVYSKLLFDGKAAKGLSFETIAKHLDRSEVACAALFYGQATASPEDIDRLSDLLEISKETLTTQMTGFPNRGQASPMPPVEPLIYRLYEIVQNYGYAYKAILNEKFGDGIMSAICFSTTVDKEVDEAGAPWVVITLKGKWLPFSRF
What is the function of this protein?
Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
What are the official names of this protein?
Cyanate hydratase, Cyanase, Cyanate hydrolase, Cyanate lyase.
What is the protein family that this protein belongs to?
Belongs to the cyanase family.
Protein: RL23_LACAC
Sequence: MDARDIILRPVITEKSTNLMDDKKYTFDVLLTATKTQVRNAVEEIFDVKVKSVNIMNVRGKDKRVGRYTGKTARRRKAIVALTDDSNDIKIFQENTEDNK
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: SYS_SYNR3
Sequence: MLDQRLLRDNPELISQQLGRRGMEVDLTKLQLIAKQERDLEEQRSNLQAEGNRTGKEVGMLIKGGAAPDSDEVKALREKGNRIKQQVAVLEEEEKGLEAKLREQLLALPNLPSADAPEGKSEADNVEVKRWGEPRQGKDLEEHWQLADRLGLFETERSVRIAQSRFITLMGDGARLERALISFMLDLHSTKGYTEVMPPILVNSASLTGSGQLPKFAEESFRCADDDLWLTPTAEVPLTSLHRDEVIAVEQLPLKYAAYTPCFRREAGSYGRDTRGLIRLHQFNKVELYWFCHPEKSAEAHEQLTLDAEAVLEALELPYRRLELCTGDMGFSAARTYDLEVWLPGAGSYREISSCSTCGDFQARRSAIRFKEGKGTQLLHTLNGSGLAIGRTMAALLENGQQPDGSIQLPAALVPYFGRERLTPQ
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TDH_SACEN
Sequence: MRALVKTSPAPGLELTELPDPTPGANDIVVQVFRTGICGTDLHIDSWDEWAARTVPTPLVIGHEFAGEVVAVGSAVTQAQVGDFVSGEGHLVCGTCRNCRAGRRHLCANTRGLGVHHNGAFAEYAVLPEQNVWVHREHVDPDVAAIFDPFGNAVHTALTFPVVGEDVLITGAGPIGLMAACVARHAGARNVVITDVSEHRLELARRVGVDLAVNVAETGIADAQAKLGMSEGFDVAMEVSGQPSALRETIENMAHGGRIAMLGLPAERFQIDWSAVVLKMLTVKGIYGREMFETWYSMSVLLQSGLDLSPVITHRFPCTRHVEAFETARAGRCGKVILDWTVR
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNME_STRP2
Sequence: MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDLNKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQLAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSDLINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGKILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLIDTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRIILLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSNARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDATPDELITQLFSQFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_BACSU
Sequence: MPRKGPVAKRDVLPDPIYNSKLVSRLINKMMIDGKKGKSQTILYKSFDIIKERTGNDAMEVFEQALKNIMPVLEVKARRVGGANYQVPVEVRPERRTTLGLRWLVNYARLRGEKTMEERLANEILDAANNTGAAVKKREDTHKMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7, BS7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.