PharMolix/UniProtQA huggingface dataset:
Protein: NDPA_PSERE
Sequence: MPIRHIIVHQIDKKPDGTPAVLHARDTELGASQAIENMLADLNESYNAKQGKAWGLFHGESGAYPFSRWLKDYLDENQDFTAFSRHAVEHLQKLMEESNLSTGGHVLFAHYQQGMTDYLTVALLHHSEGVAVNDTLDVTPAKHLDLGQLHLAARINISEWQNNKQSKQYISFIKGKNGRKVSDYFRDFIGCQEGVDAPGETRTLLKAFSDFVESEDLPEEQAREKTNTLVGYATSQAKLGEPMTLEELSGLIDEDRPKAFYDHIRNRDYGLSPEIPADKRTLNQFRRFTGRAEGLSISFEAHLLGSKIDYDENAGTLTIRNLPTQLRDQLKRG
What are the official names of this protein?
Nucleoid-associated protein.
What is the protein family that this protein belongs to?
Belongs to the YejK family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: DCAKD_MOUSE
Sequence: MFLVGLTGGIASGKSSVIQVFQQLGCAVIDVDVIARHVVQPGYPAHRRIVEAFGTEVLLENGDIDRKVLGDLIFNQPDRRQLLNSITHPEIRKEMMKETFKYFLRGYRYVILDIPLLFETKKLLKYMKHTVVVYCDRDTQLARLMKRNNLNREDAEARINAQLPLKDKARMANHVLDNSGEWSLTRRQAILLHAKLERSMEYLPLRLGFLTGLAGIASLLYLLTRYLLPSP
What are the official names of this protein?
Dephospho-CoA kinase domain-containing protein.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
Protein: RR8_CUSRE
Sequence: MGRDTIAEIITSIRNADMDRKRVVRIASTHITENIVKLLLREGFFENVRKHRENNKNFFVLTLRHRRNKKRPLRNILKLKRISRPGLRIYYKSQKIPRILGGMGVIIISTSRGIMTDREARLEGIGGEILFYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8, plastid.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
What are the subcellular locations of this protein?
Plastid.
Protein: UBIG_BARQU
Sequence: MMNETRTTIDQDEIDRFSRIAAEWWNPKGKFRPLHQLNPTRLAYIREKICLAFNRDPVSLMPFENLKILDIGCGGGLLCEPMARLGAMVVGVDAAQTNIEVAKLHATQSDLSIDYRTTIAEALADKGEKFDIILNMEVVEHVADVNLFIAATAKMLKSQGVMFVSTLNRTWKAWGLAIVGAEYILRWLPKGTHDYKKFLKPQELKNLLSKNALTVIDEIGITYNPVNDSWNRSKDMDVNYLLLAKRP
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: RK2_STIHE
Sequence: MGIRFLRSYTPGTRNRSVSDFNEITINKPEKSLTFSHHRCKGRNHRGIITCRHRGGGHKRLYRQIDFQRDKTKVPAQVLSIEYDPNRNARIALLRYPDGEKRYILHPRGLKIGETVISDVNASIQTGNTLPLRNIPLGTEVHNVEFQPGSGGQLARSAGTLVELLAKEGDFVTLRLPSKEIRLISRHCWATIGQVGHVEAYSIVVGKAGRTRWLGIRPTVRGSVMNPVDHPHGGGEGRAPIGRSRPVTPWGKPALGQKTRKPKKQSNKLILRKRKK
What are the official names of this protein?
50S ribosomal protein L2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FAR5_TYRGL
Sequence: TDRNFLRL
What is the function of this protein?
FMRFamides and FMRFamide-like peptides are neuropeptides.
What are the official names of this protein?
Extended FMRFamide-5, FMRFa-5.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRF amide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS5_SHESR
Sequence: MAKLEAQQKDDLQEKLIAVNRVSKVVKGGRIFSFTALTVVGDGNGKVGYGYGKAREVPAAIQKAMEKARRNMVTVELNAGTLHHPVKGRHTGSRVYMQPASQGTGIIAGGAMRAVLEVAGVHNVLSKAYGSTNPINIVRATVDALVHMKSPSQIAAKRGLNVDEIRG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: SYR_ANOFW
Sequence: MNIVEQMKQKLKEEIKEAVIRSGVATEADVPSVILETPKDKAHGDYSTNVAMQLARVAKKAPRMIAEDIVRHFNGEAVFVKKVDIAGPGFINFYMDNRYLTELVPAILQAGDAYGETNVGQGQKVQVEFVSANPTGSLHLGHARGAAVGDSLCNILKKAGFDVTREYYINDAGNQIANLAKSVEARYFQALGIKKDMPEDGYFGEDIIELGKKLAEEHGDKFVALDEQERLQLFREYGLAFEMDKIKKDLADFRVTFDVWYSETSLYHNGKIDKALETLREKGHIYEQDGATWFRSTTFGDDKDRVLIKQDGTYTYLLPDIAYHQDKLERGFEKIINIWGADHHGYIPRMKAAIAALGYDPDVLEVEIIQLVSLYQNGEKVRMSKRTGKAVTLRDLMEEVGLDATRYFFAMRSSDTHLDFDMDLAVSQSNENPVYYAQYAHARVCSMLRQGEEQGWRYDGDLSFTYELAEKEIDLLKKLGEFPSAVAEAAVKRSPHRMTNYIFDLASALHSFYNAEKVLDAANVEKSRARLALMKAVQITLKNALALVGVHAPEKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANC_ACIF2
Sequence: MAIFKDIAGLRQWRQSLHGTLALVPTMGNLHEGHLALVRLAANRAEHVLVSIYVNPLQFGPGEDFANYPRTLDQDLQRLHEAGCQTVFTPDDGLMYPRGRQDISIVMPPRSLSKVLCGASRPGHFAGVCTVLSKLLHMVAPEILILGEKDYQQLRIVQQMVADLNLNVQVLPGPLQREADGLAYSSRNIYLNLAERQVAPLLAETLFDLARRSTNDAAVSDLAATGWERLERAGFLPEYLELRDAQTLQSLALPQPGARWFAAARLGQIRLIDNVIIS
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ETFS_ASFM2
Sequence: MICGLILSRLVGPGCEKGGRAFFPCDPYASPFPSIKGLQLHNAQLFVQNFQNPNTPYSRLLLNWQTGTGKSIAAIAIARQFMNHYMNFIENAPWIFVVGFTRTIIQTEMLRRPELGFVSYKEVAELHRLLHIAKQSGSTTSVESRHLNGFISTLKRRLTDRNRGGFFQFYGYKEFASKLFNITSKGEEKNFDVLSLFHRSDEAEDTLNENDISQFVQKISEAETNGLIRVNQKIMEQLRGGLLIADEIHNVYNIQERNNYGIALQYVLDAFPPHQAPRAVFMSATPVTGSVMEYVDLLNLLVPRHELPNGQPLQRQQLFDNSGHSVKWKKDALALVERLSIGRVSFLLDTNTNFYPERIFAGKMLSYRDEKLPYLHFIECPMSNYQLETLKQLGPDPKISSNAYSIYDMVFPNPKFSKQTEPKAYGLFNSTETPAALSMASTDWLLENGVQIIEPSRRTPFNVSGSFLSLQPPTHISGLAFYSGKYTQMMKDILSIIREGRGKILIYHNRVRMSGVLILQEILQSNGILNEVSSPVGTTRCSICAAIRDDHTHSDHQFIPVRFTILHSEIEPAVRERSLALFNASSNLEGHQLRILIGSKVIVEGLNFQAVRYEMIMSLPLDIPRLIQVFGRVVRKNSHMELPPNERNVTIYLYVSTTPDGGPELAKYAQKLKEYILIQEGDKALRKHAIDGFTNQIKIDKPMLESLPLSPSITPANVGATVLNTFEAYGYGEQEVKTISNIIISLFMARPVWTYSELWKAVSTPKLIQGITIDNKLFSEDNFALALISLCYSKNQCKELLIQNRLCTIMHVPAKPEHLYIAAVLNHKKEPVLDIETYIRDFQPPTMHSVRITKYLEHSQTKEPFQVLYEKFQKDFQDEPIEQVLIHYPASFHYTMLEALIIDNLAGMGALVEVYKKFFIAFSKKDIQPFPDIFKIISHVPGDDNTLVGYATEDSVRLITSRKDKTWHEIPLYMLNINVKRKENDIVIGYMESKGKALKFKIRPPIQVLKKNEITDIRMLNRGAVCETRGREEQQKIANQLGISLNLTKISAIKLCLLIRNNLLQKEMEARNQPNGMQDGIRWFYLFNDKMPSLVHTS
What is the function of this protein?
Putative initation factor.
What are the official names of this protein?
Early transcription factor large subunit homolog, ATP-dependent helicase VETFS homolog.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
What are the subcellular locations of this protein?
Virion. Note=Found in association with viral nucleoid.
Protein: TPRGL_RAT
Sequence: MLQLRDTVDSAGTSPTAVLAAGEDAGAGRQGAGTPLRQTLWPLNVHDPTRRARVKEYFVFRPGTIEQAVEEIRAVVRPVEDGEIQGVWLLTEVDHWNNEKERLVLVTDQSLLICKYDFISLQCQQVVRVALSAVDTISCGEFQFPPKSLNKREGFGVRIQWDKQSRPSFINRWNPWSTNMPYATFIEHPMAGMDEKTASLCHLESFKALLIQAVKKAQKESPLPGQANNVLVLDRPLLIETYVGLMSFINNEAKLGYSMTRGKIGF
What is the function of this protein?
Presynaptic protein involved in the synaptic transmission tuning.  Regulates synaptic release probability by decreasing the calcium sensitivity of release.
What are the official names of this protein?
Tumor protein p63-regulated gene 1-like protein, Mossy fiber terminal-associated vertebrate-specific presynaptic protein.
What is the protein family that this protein belongs to?
Belongs to the TPRG1 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein. Presynaptic active zone.
Protein: HIS4_NITMS
Sequence: MKIIPAIDLMDGQVVRLYKGDPKQKTVYSDDPVSVAKKWQKAGADMLHIVDLDATIGTGSNLDLIEKISKELSIPVEVAGGLRNEEIIDRAISFSNRVVIGTMAFKDKEMLQRIAKKYDFSKIVISVDHIDGFIVTHGWQESTKTPLLDAINEFVSMGFTEFLLTNVSKDGTLEGPDLEYLEKACAVQNANVIASGGISNIDDVSDVQRKNAFAVILGKALYENKISIEEAKQLVN
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRB_CLAMS
Sequence: MQPTRSVRPFKVVSDYSPSGDQPTAIAELAGRVNAGEPDVVLLGATGTGKSATAAWLIEKVQRPTLILAHNKTLAAQLATEFRELMPDNAVEYFVSYYDYYQPEAYVPQTDTFIEKDSSVNAEVERLRHSTTNSLLSRRDVVVVSTVSCIYGLGQPEQYMNAMVALQVGMQINRDTLIRKFVSMQYQRNDVDFSRGNFRVRGDTIEIIPMYEELAIRIEMFGDEIEALYQLHPLTGDVVRKMDAVSVFPGSHYVAETEVMQRAIGTIQQELEERLAVLEREGKLLEAQRLRMRTNFDIEMMQQIGFCSGIENYSRHIDGRDAGEAPHCLLDYFPDDFLVVIDESHVTVPQIGAMFEGDSSRKRTLVEHGFRLPSALDNRPLKWNEFTERVPQTVYMSATPGKYELGMGDGVVEQIIRPTGLIDPAIVVKPTKGQIDDLLEQIRIRVEKDERILVTTLTKKMAEELTDYFAEAGVRVRYLHSDVDTLRRVELLSELRAGVYDVLVGINLLREGLDLPEVSLVAILDADKEGFLRSSTSLIQTIGRAARNVSGEVHMYADVLTDSMKRAIEETDRRREKQVAYNTEHGIDPTPLRKRIADITEILAREGEDTKKMLEGRGGGKRSPTPNLRREGKAAAGANELETIISDLNDQMLQAAGELKFELAARLRDELGDLKRELRQMEKAGHLS
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2010_XYLFA
Sequence: MESPMHLPEVIAVQQESQQMGLSVTAPELHGSLSGLLAGGGGNGPDWLAMILADAEVAAPPKGSVLERLYQATASQLEDPDFAFQLLLADDGATLAARADALFEWCRAFLGGFGLAAHSRSVLSAEGDEILRDLAKLAQASVDDFDMNEEEEDGSLEEIEEFVRVAVLLLHGDCLIGPCAPQPLN
What are the official names of this protein?
UPF0149 protein XF_2010.
What is the protein family that this protein belongs to?
Belongs to the UPF0149 family.
Protein: RS13_CORDI
Sequence: MARLAGVDLPRNKRMEVALTYIYGIGPARAAQLLEETGISPDLRTDNLTDEQVSALRDVIEATWKVEGDLRRQVQADIRRKIEIGCYQGLRHRRGLPVRGQRTKTNARTRKGPKKTIAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: TRMD_CAMJJ
Sequence: MKFSFVSLFPNLMEFYFQDSILARAKEKKLFKLNFYNPRDFSKNSYHKVDDYKIGGGAGLLMQAEPMYEVLRSIQEKKENPYFIFLNPSGKTFNQKDAKRLSKKEHIVFVCGRYEGIDERVLEIFANEVFSIGDFILTGGELPALVMCDAILRNVNGVLGNMESLEEESFENNLLEAPAFSKPFIFEKKNKKFYTPSEFLKGNHARIASLKTTLASCKTKFFRPDLFLEHERKK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCD15_HUMAN
Sequence: MLGSMARKKPRNTSRLPLALNPLKSKDVLAVLAERNEAIVPVGAWVEPASPGSSEIPAYTSAYLIEEELKEQLRKKQEALKHFQKQVKYRVNQQIRLRKKQQLQKSYERAQKEGSIAMQSSATHLTSKRTSVFPNNLNVAIGSSRLPPSLMPGDGIEDEENQNELFQQQAQALSETMKQARHRLASFKTVIKKKGSVFPDDGRKSFLTREEVLSRKPASTGINTGIRGELPIKVHQGLLAAVPYQNYMENQELDYEEPDYEESSSLVTDEKGKEDLFGRGQQDQQAIHSEDKNKPFSRVQKVKFKNPLFVLMEEEEQKQLHFEGLQDILPEAQDYFLEAQGDLLETQGDLTGIQSVKPDTQAVEMKVQVTEPEGQAIEPEGQPIKTETQGIMLKAQSIELEEGSIVLKTQDFLPTNQALLTKNQDVLLKDHCVLPKDQSILLKYQDQDFLPRDQHVLHKDQDILPKYQDQNFLPKDQNFLSRDQHVLPKDQDILPKYQDQNFLPKDQNFLSRDQHVLPKDQNILPKYQGQDFLPKDQDFLSRDQHVLPKDWNILPKCQDQDFLPRDQGVLPKDQNILPICQDQDFLPRDQGYLPKDQNILPICQDRDFLPRDLHVLSNDQNILPKCQDQDFLPKYQKVHFKEPYSDMTDEKGREDFSLADYQCLPPKSQDQDDIKNQQPASFMREERVREELPLDYHQYVVPKIQDQDSPREQNKHIKLPSSFEKWEIARGNTPGVPLAYDRYQSGLSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRRLFMDIEREQVKEQQRQKEQKKKIEKIKKKREQECYAAEQRILRMNFHEDPYSGEKLSEILAQLQLQEIKGTREKQQREKEYLRYVEALRAQIQEKMQLYNITLPPLCCCGPDFWDAHPDTCANNCIFYKNHRAYTRALHSFINSCDVPGGNSTLRVAIHNFASAHRRTLKNL
What are the official names of this protein?
Coiled-coil domain-containing protein 15.
Protein: PTH_STAAN
Sequence: MKCIVGLGNIGKRFELTRHNIGFEVVDYILEKNNFSLDKQKFKGAYTIERMNGDKVLFIEPMTMMNLSGEAVAPIMDYYNVNPEDLIVLYDDLDLEQGQVRLRQKGSAGGHNGMKSIIKMLGTDQFKRIRIGVGRPTNGMTVPDYVLQRFSNDEMVTMEKVIEHAARAIEKFVETSRFDHVMNEFNGEVK
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT3_ARATH
Sequence: MSGNKEEEDPRIHGIKTKIRVVPDFPKKGIMFQDITTVLLDPKAFKDTIDLFVERYRDKNISVVAGIEARGFLFGPPIALAIGAKFVPLRKPKKLPGETIFEEYELEYGNDRLEMHIGAVEAGDRALVVDDLIATGGTLCAAINLLERVGAEVVECACVIELPELKGRQRLKGKPLCMLVEYR
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.  May contribute to the recycling of adenine into adenylate nucleotides and the inactivation of cytokinins by phosphoribosylation.  Possesses low activity toward adenine and cytokinins.
What are the official names of this protein?
Adenine phosphoribosyltransferase 3.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIBL_METSF
Sequence: MEKKKIVVTAGTFDILHPGHYEILKFAKSLGDELIVIVARDETVKKLKGRKPIIPEEQRREMVEALKPVDKAVLGSLKNKLEPILKLKPDIIVLGPDQTTFDEETLKQELAKYNLYPEIVRFRGYKKCPFHSSFDIVKEIIRRFCSKEIKI
What is the function of this protein?
Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
What are the official names of this protein?
FAD synthase, FMN adenylyltransferase, Flavin adenine dinucleotide synthase.
What is the protein family that this protein belongs to?
Belongs to the archaeal FAD synthase family.
Protein: SYFA_SALG2
Sequence: MSHLAELVANAAAAINQASDVAALDNVRVEYLGKKGHLTLQMTTLRDLPPEERPAAGAVINAAKEQVQQALNARKAELESAALNARLAAETIDISLPGRRIENGGLHPVTRTIDRIESFFGELGFTVATGPEIEDDYHNFDALNIPGHHPARADHDTFWFDATRLLRTQTSGVQIRTMKAQQPPIRIIAPGRVYRNDYDQTHTPMFHQMEGLIVDTNISFTNLKGTLHDFLRNFFEEDLQIRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRNVGIDPEIYSGFAFGMGMERLTMLRYGVTDLRSFFENDLRFLKQFK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_CAMJR
Sequence: MRLFGTDGVRGKAGEFLDSFLAMRLAMAAGIYFKDKSITNNILVGKDTRRSGYMIENAIVSGLTSIGYNVIQIGPMPTPAIAFLTEDMRCDAGIMISASHNPYYDNGIKFFDAHGNKLSEDIEKKIEEIYFDDKLIQASKVDMEKIGQAKRIDDVIGRYIVSIKNSFPKDLTLKSLRVVLDVAHGAAYKVAPTVFKELGAEVIVMSDKPNGLNINENCGALHPVNLAAEVKRLRADVGFAFDGDADRLVVVDEKGEVANGDSLLGVLALYLKEQGKLQSSVVATIMSNGALKEFLNKHGIELDTCNVGDKYVLEKLKANGGNFGGEQSGHIIFSDYAKTGDGLIAALQFSALMLSKKKSASSILGQVKPYPQLLINLKIAEKKDLDKIKGLKELKKDLENKNINTLFRYSGTENLIRLLLEARDIKLLEKEMKNVVEFFKKALNG
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: IMDH_CANAX
Sequence: MVFETSKATSYLKDYPKKDGLSVKELIDSTNFGGLTYNDFLILPGLINFPSSAVSLETKLTKKITLKSPFVSSPMDTVTEENMAIHMALLGGIGIIHHNCTSEEQAEMVRKVKKYENGFINDPVVISPEVTVGEVKKMGEVLGFTSFPVTENGKVGGKLVGIITSRDIQFHEDNKSPVSEVMTKDLVVGKKGISLTDGNELLRSSKKGKLPIVDAEGNLVSLISRTDLQKNQDYPNASKSFHSKQLLCGAAIGTIDADRERLDKLVEAGLDVVVLDSSNGSSVFQLNMIKWIKEKYPELQVIAGNVVTREQAALLIEAGADALRIGMGSGSICITQEVMACGRPQGTAVYGVTEFANKFGVPCIADGGIGNIGHITKALALGASCVMMGGLLAGTAETPGDYFYRDGKRLKTYRGMGSIDAMQQTNTNANASTSRYFSEADKVLVAQGVSGSVVDKGSITKFVPYLYNGLQHSLQDIGIKSIDELRENVDNGEIRFEFRTASAQFEGGVHGLHSYEKRLHN
What is the function of this protein?
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
What are the official names of this protein?
Inosine-5'-monophosphate dehydrogenase, IMP dehydrogenase, IMPD, IMPDH.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYSY_SHIF8
Sequence: MKQYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLQDGFPLVTTKRCHLRSIIHELLWFLQGDTNIAYLHENNVTIWDEWADENGDLGPVYGKQWRAWPTPDGRHIDQITTVLNQLKNDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLEVGDFVWTGGDTHLYSNHMDQTHLQLSREPRPLPKLIIKRKPESIFDYRFEDFEIEGYDPHPGVKAPVAI
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YGV4_SCHPO
Sequence: MSENPAHKDLDSLQVDEKAKSWIAEKVEEELRRLESVGAKAIPLDVKNYSVMLDEDTDTVVNRIELMTSFDFDHVQQILLSAVQPYPYDKNLMFVYLVILTPLPHPMLIPYLFAPKVVGKNLLPRADGLVENTLKRWTFINDKLKRSDTVVREFQEIEEEATK
What are the official names of this protein?
Uncharacterized protein C354.04.
Protein: NU2M_VARNE
Sequence: MNPLINFILLSSMIAGTILTTTSHHWVSAWLGLELNTLAIIPIISMTHHPRATEASTKYFLIQAASSALVLLSGIINAHLHGSWDISQLSDNFSKIALTTALATKLGLAPIHFWLPEILQGVPILTALIIATWQKIAPMALLIMIWDLIPTPITLIMGLTSTIVGGLGGLNQTQLRKTMAFSSIAHLGWMITMMTIAPNLTLLNLILYIPMTSLTMLIMHLTMSKTLQNAMLIPSHSLTATSLFLLSLLSLGGLPPLSGFIPKWLILQELTIHNLTPMAFMMAITALLSLMFYLRITYISTMTLPPSTTPLKNTWRFKSHQNTSTLPLLSLISIFLLPITPTLTQ
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CADH5_MOUSE
Sequence: MQRLTELATALGAFLGLLAVAAMAGPNFPQIDTPNMLPAHHRQKRDWIWNQMHIDEEKNESLPHYVGKIKSNVNRQNAKYVLQGEFAGKIFGVDANTGNVLAYERLDREKVSEYFLTALIVDKNTNKNLEQPSSFTVKVHDINDNWPVFSHQVFNASVPEMSAIGTSVIRVTAVDADDPTVAGHATVLYQIVKGNEYFSIDNSGLIFTKIKNLDREKQAEYKIVVETQDALGLRGESGTATVMIRLEDINDNFPVFTQSTYTFSVPEDIRVGKPLGFLTVVDPDEPQNRMTKYSIMQGEYRDTFTIETDPKRNEGIIKPTKSLDYEVIQQYTFYIEATDPTIRYEYLSSTSGKNKAMVTINVLDVDEPPVFQRHFYHFKLPENQKKPLIGTVVAKDPDKAQRSIGYSIRKTSDRGQFFRITKQGNIYNEKELDRETYAWYNLTVEANELDSRGNPVGKESIVQVYIEVLDENDNPPEFAQPYEPKVCENAAQGKLVVQISATDKDVVPVNPKFKFALKNEDSNFTLINNHDNTANITVKYGQFNREHAKFHYLPVLISDNGVPSLTGTSTLTVGVCKCNEQGEFTFCEEMAAQAGVSIQALVAIFLCILTITVITLLIILRRRIRKQAHAHSKSALEIHEQLVTYDEEGGGEMDTTSYDVSVLNSVRGGSTKPLRSTMDARPAVYTQVQKPPRLAPGLHGGPREMATMIDVKKEEADNDGGGPPYDTLHIYGYEGAESIAESLSSLSTNSSDSDIDYDFLNDWGPRFKMLAELYGSDPQEELII
What is the function of this protein?
Cadherins are calcium-dependent cell adhesion proteins (By similarity).  They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (By similarity).  This cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions (PubMed:9220534, PubMed:20332120).  It associates with alpha-catenin forming a link to the cytoskeleton (By similarity).  Acts in concert with KRIT1 and PALS1 to establish and maintain correct endothelial cell polarity and vascular lumen (PubMed:27466317).  These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B (By similarity).  Required for activation of PRKCZ and for localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction (By similarity).
What are the official names of this protein?
Cadherin-5, Vascular endothelial cadherin, VE-cadherin.
What are the subcellular locations of this protein?
Cell junction. Cell membrane; Single-pass type I membrane protein. Note=Found at cell-cell boundaries and probably at cell-matrix boundaries. KRIT1 and CDH5 reciprocally regulate their localization to endothelial cell-cell junctions (By similarity).
Protein: EF1G2_ORYSJ
Sequence: MALVLHAGSGNKNAFKALIAAEYSGVKVELVKNFQMGVSNKTPEFLKMNPIGKIPVLETPDGPVFESNAIARYVTRSKADNPLYGSSLIEYAHIEQWNDFSATEVDANIGKWLYPRLGIAPYVAVSEEAAIAALKRSLGALNTHLASNTYLVGHSVTLADIVMTCNLYMGFARIMTKSFTSEFPHVERYFWTMVNQPNFKKVLGDVKQAESVPPVQKKAPPPKEQKPKEAKKEAPKEAPKPKAVEKPEEEEEAPKPKPKNPLDLLPPSKMILDEWKRLYSNTKTNFREVAIKGFWDMYDPEGYSLWFCDYKYNDENTVSFVTMNKVGGFLQRMDLCRKYAFGKMLVIGSEPPFKVKGLWLFRGPEIPKFVMDEVYDMELYEWTKVDISDEAQKERVSAMIEDLEPFEGESLLDAKCFK
What is the function of this protein?
Probably plays a role in anchoring the complex to other cellular components.
What are the official names of this protein?
Elongation factor 1-gamma 2, EF-1-gamma 2, eEF-1B gamma 2.
Protein: DHR13_HUMAN
Sequence: MEALLLGAGLLLGAYVLVYYNLVKAPPCGGMGNLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSQERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNAGISSCGRTREAFNLLLRVNHIGPFLLTHLLLPCLKACAPSRVVVVASAAHCRGRLDFKRLDRPVVGWRQELRAYADTKLANVLFARELANQLEATGVTCYAAHPGPVNSELFLRHVPGWLRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGRYFANCHVEEVPPAARDDRAAHRLWEASKRLAGLGPGEDAEPDEDPQSEDSEAPSSLSTPHPEEPTVSQPYPSPQSSPDLSKMTHRIQAKVEPEIQLS
What is the function of this protein?
Putative oxidoreductase.
What are the official names of this protein?
Dehydrogenase/reductase SDR family member 13, Short chain dehydrogenase/reductase family 7C member 5, Protein SDR7C5.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL33_XYLFT
Sequence: MAGKRDKIRLISSADTGHFYTTDKNKKNTPGKLEFKKYDPRVRRHVIYKEGKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.