PharMolix/UniProtQA huggingface dataset:
Protein: Y3189_MYCTU
Sequence: MKLADAIATAPRRTLKGTYWHQGPTRHPVTSCADPARGPGRYHRTGEPGVWYASNKEQGAWAELFRHFVDDGVDPFEVRRRVGRVAVTLQVLDLTDERTRSHLGVDETDLLSDDYTTTQAIAAARDANFDAVLAPAAALPGCQTLAVFVHALPNIEPERSEVRQPPPRLANLLPLIRPHEHMPDSVRRLLATLTRAGAEAIRRRRR
What is the function of this protein?
Probable toxic component of a type II toxin-antitoxin (TA) system.  Degrades NAD(+) by phosphorolysis.  Neutralized by its cognate antitoxin Rv3188.
What are the official names of this protein?
Probable NAD(+) phosphorylase Rv3189, Mycobacterial cidal toxin Rv3189.
What is the protein family that this protein belongs to?
Belongs to the MbcT/ParT/Res family.
Protein: SSRP_ACET2
Sequence: MAKEEKRVVAQNRKARHDYFIEQTIEAGIVLSGTEVKSIRAGKVSLKDSYANVKNGEVFIYGMHISPYEQGNIFNKDPLRDRKLLLHRAEINKLIGYIQQKGMTLVPLEVYFKNGKVKIELGIAKGKKLYDKREDIAKRDALREIDRRLKENFR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: KITH_COXBU
Sequence: MAKLHFYYSAMNAGKSTTLLQSSYNYNERGMDTLVFLPVVDDREGERKIATRIGLSGKTIALTKDTNLFKCISDKLAENPNIRCVLVDEAQFLTKSQVEALALVTDELNLPVLAYGIRTDFQGEPFEGSVYLLAWADLLIEIKTICHCGRKATMNLRIDDEGNPIREGEQIRLGGNDRYTATCRKHFRLGQPTQTK
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURQ_METST
Sequence: MTDVADVNVGIIRFPGTNCDRDIEYAVNLVGANSHYIYWNETDLSQMDVVIIPGGFSYGDYLRAGSIAGITPIIDAIKDFAKKENPVLGICNGAQILGEIDLVPGVFIENENAKFICKSKKLKVNTTRTPFTKLYKKNEVIDLPIAHKEGRYYTDNLETLYDNNQIVLTFEDGNPNGSLDNITGVCNVDGNVVAVMPHPERAVEKLLRSEDGLKFFKSFLD
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NOT3_CANAL
Sequence: MSNRKLQKEIDIIFKKIQEGLQDFDYHYERYESIQNTEDDSDNQREKEKLANDLKKEIKKLQKFREQIKHWLQNDTVHTLGPVGTSYESKLAENKSLIEDSMETYKLVEKQSKLKTFSNQSIMMTFMDSTNGDDDDDDDDSDDDELFSGSDEDEEDEYSDLPEDAVNAIHFFKDSILQLREQTHKLDHEYEKLAAKKLRKNNLATIEAKKEKIQSTIGNNKFHQKKLKKLLRQLTSGVVTEFNLIWLLKDDLNKYLESNGDYEFTRETELYDDIFNQIAAVEEDYSEIHEDNHDHSHSHLEKTSTANGTHHESATTTATAAKNSSVTTRTSPSPILTKANGHIKELSVESGSPTTSRSKLSKIHTNTSQSSTHSNTSSSTHAQAPRQSPELTSPAIVKTLRPATAPSKPVGTLKWSAAAAAAIPDVQEKPELVETESNGSSVHKTVSKDQYEEKINYQSPAPTQQQQQPQTSVESKTLSTTQSLASSITDNINLDKYKEVIKNSNLTKTELGLFSDMNLARVPPGIQDLVISFASKRNNDNFKVLVDSTEFNQFALPLHKPYLPEIVQPSYYSQYTSTSFKHPTPLVKFQSYWNQVRANFGFQKLMDEIKSLTLQNNADNLPIIAELTFVLFYGFYYGVTPAENLIAESYLFELGWKPYKNQSEDGSNNLSTGSISLSDINGSKSKSNRSSNYYFWFKRVKLISRGEDMGQPSNIEFGDYQVFDLSFWEIFVKYGFKFDYNFCQMEPSKTLF
What is the function of this protein?
Acts as component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover.  The NOT protein subcomplex negatively regulates the basal and activated transcription of many genes.  Preferentially affects TC-type TATA element-dependent transcription.  Could directly or indirectly inhibit component(s) of the general transcription machinery (By similarity).  Required for yeast cell adherence to silicone substrate, but nor required not required for buccal epithelial cell adherence or virulence in mouse systemic infection.
What are the official names of this protein?
General negative regulator of transcription subunit 3.
What is the protein family that this protein belongs to?
Belongs to the CNOT2/3/5 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GLGA_LEPBA
Sequence: MKILHASAEYFPYTKMGGLADMLASLTKEQSRTEEVYVALPLIGKLGKEPNWTGKEVGALLPQDAKEETIAVSLLAKARFREAIESGVKLYFFDSELFSGLNSIYGQADEHYRFAIFSYACYALSQILQVDVFHAHDWHTALSLTLQKNSTKPIPSLFTIHNLAYQGDHPFWMTGFLKEDPFYLITSPFDQDGKCNYMKAGILSAGQITTVSPGYREETLREPNGFGLSYVLKKRKADYTGILNGIDPDEWNPKVDKRIFQTYHLQNWKEGKRKNKEHLYREIGRPNVSLDLPLIGLIGRLTYQKGFPTFLQAFLERRHLPHRYVVLGSGDPETENAFFHLSDMMPDVFYFYKGYNESLAHQIEAASDFFLMPSLFEPCGLNQMYSHVYGTIPIVSRVGGLRDTVDESIDIQFKTGIVFEPNDKSSLGYALERANDLFVSPERDHVVKNMMNLDWTWTKRKLEYDRVYKIAIELLE
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: EF1A_HALWD
Sequence: MSDKPHQNLAIIGHVDHGKSTLVGRLLFETGSVPEHVIEQHREEAEEKGKGGFEFAYVMDNLAEERERGVTIDIAHQEFDTEDYYFTIVDCPGHRDFVKNMITGASQADNAVLVVAADDGVAPQTREHVFLARTLGINELIIGVNKMDIVDYSEETYEDVKTEVDKLLKQVQFNANDAKYIPISAFEGDNVAESSDNTSWFDGPSLLEALNNLPEPQPPTDAPLRLPIQDVYTISGIGTVPVGRVETGTVSPGDDVSFQPSDVGGEVKTVEMHHEEVDQAGPGDNVGFNVRGIGKDDIRRGDVCGPSSNAPTVAETFKAQVVVMQHPSVITAGYTPVFHAHTAQVACTIESIDQKLDPASGEVAEEDPDFIKSGDAAVVTVRPQKPLSIEPSNEIPELGSFAVRDMGQTIAAGKVLEVDER
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha, EF-1-alpha, Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_BAUCH
Sequence: MLQPKRTKFRKMQKGRNRGLALDTNVNFGTFGLKAVDRGRLTARQIEAARRTITRAIKRQGKIWIRIFPDKPITEKPLEVRMGKGKGNVENWVALIKPGKILYEIDGVTEELAREALRLAAAKLPMKTTFANKMILS
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: TRPA_STRPI
Sequence: MPKTLTEKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLEDLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTYFNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGIERQKELIEGAEGFIYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQADLERFNAVSDGVIVGSKIVKALHQGEPIQDFIKQAVAYQK
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: RNH2_PSEP1
Sequence: MQIGLDFNLVEDLVAGVDEVGRGPLCGAVVTAAVILDPARPILGLNDSKKLTEARREALFDEICEKALSFCIARAEVEEIDSLNILQATMLAMQRAVEGLHITPKLALIDGNRCPKLAVPAAPVVKGDSQVPAIAAASILAKVTRDREMSAFELIYPGYGIGGHKGYPTPVHLEALARLGPTPIHRRSFAPVRAAWEVREGVTDSLI
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MT1_MOUSE
Sequence: MDPNCSCSTGGSCTCTSSCACKNCKCTSCKKSCCSCCPVGCSKCAQGCVCKGAADKCTCCA
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.
What are the official names of this protein?
Metallothionein-1, MT-1, Metallothionein-I, MT-I.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 1 family.
Protein: DPNPH_ARATH
Sequence: MAVDSLETEIDTAVRVVHLASSLCVKVQEKLHLPNGGHVKSKDDDSPVTVADFGVQAIVSWVLAEVFGDQNLSIVAEEDTETLSEADSLGLLGAVSNAVNEALSEAQNYGLPKPVKPLGSSEILKAISRCNSVGGPKGRHWVLDPVDGTLGFVRGDQYAVALALIENGKVLLGVLGCPNYPVKKECLSNGCNQAMKTKAVAGSVSKGCVMYAKRGSGQAWMQPLIVGGIPESATLLKVSSVDDPVLATVCEPVERANSNHLFTAGLANSMGVRKQPMRVYSMVKYAAIARGDAEVFMKFAQSSYKEKIWDHAAGVVIVEEAGGVVTDAGGRNLDFSKGVYLEGLDRGIIACSGQVLHEKIIGAVYASWESSSL
What is the function of this protein?
Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP (PubMed:10205895).  May regulate the flux of sulfur in the sulfur-activation pathway by converting PAPS to APS (By similarity).  Prevents both the toxicity of PAP on RNA processing enzymes as well as the product inhibition by PAP of sulfate conjugation.
What are the official names of this protein?
PAP-specific phosphatase HAL2-like, AtAHL, 3'(2'),5'-bisphosphate nucleotidase, 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase, DPNPase, Halotolerance protein.
What is the protein family that this protein belongs to?
Belongs to the inositol monophosphatase superfamily.
Protein: SPRTL_BACAA
Sequence: MDEQEIQRLVEEVSLQYFGMPFLHKAMFNSRLRTTGGRYLLNTHNIELNYRYYEMYGKEELVGIVKHELCHYHLHITGRGYKHRDKDFRELLKAVDAPRFCKRMVNAEKEKRVYVYECMECLLQYVRRRQINTKRYVCGKCKGKLNLIKKTS
What are the official names of this protein?
Protein SprT-like.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMH_PARP8
Sequence: MRFDLERPLQSAAAHRVAVLLINLGTPDAPTPRAVRRYLAQFLSDPRVVEIPSLVWQIILRLFILPFRGVASAKKYASVWMPEGSPLRVHTQKQVEGLRHLLHLNDYTVIVEYAMRYGTPDIPAMLNQLKLAGAERILLMPMYPQYSASTTATAFDAAFVALRRMRNQPEIRTVRQYADHPAYIAALAAQVNHYWHAHGRPDFAAGDKLVLSFHGVPKRTLDLGDPYHDQCQQTATLLMHALGLTSVECRVTFQSRFGKAEWLQPYTAPTLKELGAAGVHRADVFCPGFTADCLETIEEIGMEVRDEFLHAGGKVFHAIPCLNAAPAWIAALGEIVAQHLQGWPVQAATPQSASVA
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_PHYS1
Sequence: METETKQAKAIASKVSIAPRKVRLVIDLIRGKNIAQAQAILTFTSKVAAPVILKLLNSAVANATNNLKLNHEQLYVKEVFVNEGLRLKRIFPRAKGSGDMIKKRTSHITLVVALKNKQILKEAQDGSENQS
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: GCSH_COXB2
Sequence: MAEFPAELYYSKNHEWMRKESDETFTVGITDHAQEQLGDLVFVELPETNIHVDAGDEVAVVESVKTAADVYSPLSGKVIEINNALENEPATVNRDPYGDGWLYRITIDDEKELNDLLDADGYQTLIEAES
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: DPOL_BPM2
Sequence: MSRKMFSCDFETTTKLDDCRVWAYGYMEIGNLDNYKIGNSLDEFMQWVMEIQADLYFHNLKFDGAFIVNWLEQHGFKWSNEGLPNTYNTIISKMGQWYMIDICFGYKGKRKLHTVIYDSLKKLPFPVKKIAKDFQLPLLKGDIDYHTERPVGHEITPEEYEYIKNDIEIIARALDIQFKQGLDRMTAGSDSLKGFKDILSTKKFNKVFPKLSLPMDKEIRKAYRGGFTWLNDKYKEKEIGEGMVFDVNSLYPSQMYSRPLPYGAPIVFQGKYEKDEQYPLYIQRIRFEFELKEGYIPTIQIKKNPFFKGNEYLKNSGVEPVELYLTNVDLELIQEHYELYNVEYIDGFKFREKTGLFKDFIDKWTYVKTHEEGAKKQLAKLMLNSLYGKFASNPDVTGKVPYLKDDGSLGFRVGDEEYKDPVYTPMGVFITAWARFTTITAAQACYDRIIYCDTDSIHLTGTEVPEIIKDIVDPKKLGYWAHESTFKRAKYLRQKTYIQDIYVKEVDGKLKECSPDEATTTKFSVKCAGMTDTIKKKVTFDNFAVGFSSMGKPKPVQVNGGVVLVDSVFTIK
What is the function of this protein?
Polymerase responsible for protein-primed viral DNA replication by strand displacement with high processivity and fidelity.  To start replication, the DNA polymerase forms a heterodimer with a free primer terminal protein (TP), recognizes the replication origins at both 5' ends of the linear chromosome, and initiates replication using as primer the OH-group of Ser-232 of the TP.  This polymerase possesses three enzymatic activities: DNA synthesis (polymerase), primer terminal protein (TP) deoxynucleotidylation, which is the formation of a covalent linkage (phosphoester) between the hydroxyl group of a specific serine residue in TP and 5'-dAMP, a reaction directed by the second T at the 3' end, and 3' to 5' exonuclease activity.  Exonuclease activity has a proofreading purpose.
What are the official names of this protein?
DNA polymerase, Gene product 2, gp2, Protein p2.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
Protein: MECA_STRP7
Sequence: MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMSPDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFAKLADLVVFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDSDISRSVLQEYGQVLMSHDAVLNLQKIG
What is the function of this protein?
Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
What are the official names of this protein?
Adapter protein MecA.
What is the protein family that this protein belongs to?
Belongs to the MecA family.
Protein: YGQ3_SCHPO
Sequence: MGRANGKRRNHRKNRMNPIQKKGFLEQEIPLNNSEAALPLLSRLDNPEIKERSWACSAISNIIASCTEGRLYLLKNGLVSKLIDRISDDSVEVVVEATGALRNLAIEEGYSICMDMYRKNVLAPLQIWQTKIVQTLDEATEGKNVLETYEDRSTFSCLCAIAENISSLLVNLGETTSQVIKVLNQKNTLVFLSRLLIPEAKIPQSVQEMALQAFFTLTDDNDDGIITWIQNSSDFALKTINQIYLYFSYPSCLVRVYSIGIIYNIYQSGFVNKKMESVVKGISLFDSFIPEALPILSDLLPSEENYRNLVRQVYDKDTYFKTKKDDLTLSSELLVIPATLELISSMTSLLQSLADGTDELEEQEDSLMEDEDLSYMDDMSNVVNEDENLIIDEIPSNTPQKGNFKLVEYMLDHVLPKVITYCVVAFEFSSEEIPSNLSNYFQEVGDRTIECLNNISWSCNSVFVESSEAFTRWKLSAGKILQWIFQTIFLRLGLGVWPFSSEGFTTACSLLWSVSKPFPAEIQVLSVDDISTLILFSSTHGSLEAQSRLLGAFGSLGRCGNIQINQLLGQTLMSCVIASDPNPLLAVEALNAIFDVYGDKSYPYDAPVFKGSGYLSQLSEALPRLKNMVKKIDRRREKHLRFRAEEALENLESFIDYKHAEYAS
What are the official names of this protein?
Uncharacterized ARM-like repeat-containing protein C1703.03c.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: P210L_MOUSE
Sequence: MIAFGAPRRRSFGLLFSLAPHLFFLFLIGTLANKLNVPQVLLPFSREPGRVPFLLEAQRGCYIWHSTHHDAVTIQPLYENGTSCSQRAVLVAESTQPIRLSSIILAREVVTDHELRCDVKVDVIDNIEIVSRTRELYVDDAPLELMVRALDSKGNTFSTLAGMVFEWSIAQDNESSREELSSKIRILKYSEAEYSPPDYIIEMEKQERQGDVILVSGMRTGAAVVKVRIYEPFYKKVAAALIRLLVLENIFLIPSHDTYLLVGAYIKYRVAKMVQGRMTEVNFPLEHYTLELQDHRLTNGGLPSKSVALLDEKTAMVTAVQLGQTNLVFVHKNVHMRSVSGLPNSTIYVVEPGFLGFSIHPGGRWSLEVGQVYVITVEVFDKSSTRVYISDNLKITFQFSKEYFEEQLSTSNGSYHVVKALKDGVVVINATLTSSLQERNSSQPKTYQISHQQEVKIYFPIQLKPSFLAFPHHPLGISNRFTVQVEGGSGNFTWSSSNETVAMVTTKGVVTAGQVRGNSTILARDVQNPSRSGDIKVYVMKLNKMELLPFQADVEIGQIIEVPIAMYHVNTETKEAIAFTDCSHLPLDLNSDKQGVFTLFKEGIQKPGAMHCSSVHIAATSPGHTLVTVSVTGHEEHAWSSATFAAYEPLKALNPVDVALVTWQSVKEMVFEGGPHPWILEPSRFFLELSMEKAEAIRVAEVRLPAKRKQNQYVYRVLCLELGEQVLTFRIGNHPGVLNPSPSVEKVQVRFICAHPASMLVTPMYKAPSGTQPCPLPQYNKQLIPVSSLRDSVLELAVFDQHGRKFDNFSSLMLEWKSSNETLAHFEDSKSVEMVARDDGSGQTRLHGHQILKVHQMKGTVLIGVNFAGYSGKKSPKGISNSPRSAGVELILVEDVTVQPENATIYNHPDVKEIFNLVEGSGYFLINSSEQDIVTITYREAESSVQLVPAHPGFLTLEVYDLCLAYLGPAVAQIRVSDIQELELDLIDKVEIGKTVLVVVRVLGSSKHPFRNKYFRNMEVRLQLASAIVTLRLMEDQDEYSENYMLRAVTVGQTTLVAIATDRMGKKFTSAPRHIEVFPPFRLIPEKMTLIATNMMQIMSEGGPQPQSIIHFSISNQTVAVVNRRGQVTGKSVGTAVLHGTIQTVNEDTGKVIVFSQDEVQIEVVQLQAVRILAAATRLVTATEMPVYVMGVTSTQTPFSFSNASPLLTFHWSMSKRDVLDLVPRHSEVFLQLPAENNFAMVVHTKAAGRTTIKVTVRSENSSSGQLEGNLLELSDEIQILVFEKLQLFYANCQPEQILMPMNSQLKLHTNREGAAFVSSRVLKCFPNSSVIEEDGGGLLRSGSIAGTAVLEVTSIEPFGVNQTTITGVQVAPVTYLRLSSYPKLYTAQGRTLSAFPLGMSLTFIVEFYNNIGEKFHTHNTRLYMALNRDDLLLIGPGNRNYTYMAQAVNKGVTVVGLWDQRHPGMADYIPVAVEHAIEPDTKLIFVGDVICFSTQLVNQHGEPGVWMISTNNIVQTDTATGVGVARNPGTATIFHNIPGVVKTFREVVVNASSRLTLSYDLKTYLTNTPNATAFKLFISTGRNVNLKGSCTPSQALAIEKVLLPETLMLCHVQFSNTLLDIPASKVFHIHSEFSVEKGVYVCLIKVRQESKELRQVLSVADTSVYGWATLVSERGKNGMQRILIPFIPGFYMNQSEFVLGHKDTGELRILGVERVLESLEVFHSSPFLAVSGYKHSMLTTGLTVYLVRIVNFTAFQQMSSPAFINVSCALTNQQEAVIVRAKDASGADHCEDSGVFKNFVGSYQILLFTLFAVLASTSFIFLAHNAFLNKVQTIPVVYVPTTGTTQPGSYTATCSPPHFLSSRPPLVQSRLQHWLWSIKH
What are the official names of this protein?
Nuclear pore membrane glycoprotein 210-like, Nucleoporin 210 kDa-like, Nucleoporin Nup210-like.
What is the protein family that this protein belongs to?
Belongs to the NUP210 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL35_CHRVO
Sequence: MPKMKTKSSAKKRLKVLGGGGFKRAHAFKRHILTKKTTKNKRQLRGTSMVDATNVASVRAMMPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: CMOA_SALCH
Sequence: MSHRDTLFSAPIARLGDWTFDERVAEVFPDMIQRSVPGYSNIISMIGMLAERFVQPNTQVYDLGCSLGAATLSVRRNIRHEHCRIIAVDNSPAMIERCRRHIDAYKAPTPVEVVEGDIRDITIENASMVVLNFTLQFLEPAERQALLDKIYQGLNPGGALVLSEKFSFEDAKVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVETHKSRLRKAGFEHSELWFQCFNFGSLVALKAGVAA
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: DBP9_ASPTN
Sequence: MKRKLDANDVPSPEAADDSVKNDVDNLDFESLNLDPRLRQALVKEKFTKPTLVQAKAIPLALEGKDILARAKTGSGKTAAYVLPILQTILQKKANDPSLKATTGLILVPTRELAEQVQNVITTFAAFCGKDVRSVNLTQKVSDAVQRTMLADYPDLIVSTPSRVIANLGSSALSLENLTHLVIDEADLVLSYGYDEDINALAKAIPRGVQTFLMSATLTAEVDTLKGLFCRSPVILKLEDKDDQGSGVSQFVVKCAEDEKFLLTYVIFKLQLIKGKVIIFVGDVDRCYRVKLFLEQFGIKSCVLNSELPVNSRLHVVQEFNKGVYDIIIAADEQEVMGARKSKKSKEAEENDAGEAAGSSDEDEGEAQKPSTTRSDKPSEKRRKTAGKDKDYGISRGIDFQNVACVLNFDLPTTSKSYTHRIGRTGRAGKTGMALSFVVPADQFGKHKPTSFPTAKHDETVLAKITKRQAKLGHEVKPYHFEMKQVDAFRYRMTDALRSITRLAVQEARAREIRQELIKSEKLKRHFEENPEELRQLRHDDELRSARIQPHLKHIPDYLMPSKGKKGISSENVGYVGFRKTSENRIRKAREKNRGKGKGRNYAGVKKVDPLKTFNRGRK
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase dbp9.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX56/DBP9 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: FABG_STAEQ
Sequence: MNKSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKDKAEAVVEEIKAKGVESFAIQANVAKGDEVKEMIKEVVSQFGSVDVLVNNAGITKDNLLMRMKEQEWDDVIDTNLKGVFNCIQKVTPQMLRQRSGAIINLTSIVGAMGNPGQANYVATKAGVIGLTKTAARELASRGITVNAVAPGFIVSDMTNALSDDLKDQMLEQIPLKRFGEDTDIANTVAFLASDKAKYITGQTIHVNGGMYM
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
What are the official names of this protein?
3-oxoacyl-[acyl-carrier-protein] reductase FabG, 3-ketoacyl-acyl carrier protein reductase, Beta-Ketoacyl-acyl carrier protein reductase, Beta-ketoacyl-ACP reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: HAND2_HUMAN
Sequence: MSLVGGFPHHPVVHHEGYPFAAAAAAAAAAAASRCSHEENPYFHGWLIGHPEMSPPDYSMALSYSPEYASGAAGLDHSHYGGVPPGAGPPGLGGPRPVKRRGTANRKERRRTQSINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDLLAKDDQNGEAEAFKAEIKKTDVKEEKRKKELNEILKSTVSSNDKKTKGRTGWPQHVWALELKQ
What is the function of this protein?
Essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries.  Required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway.  Also plays an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud.  Is involved in the development of branchial arches, which give rise to unique structures in the head and neck.  Binds DNA on E-box consensus sequence 5'-CANNTG-3' (By similarity).
What are the official names of this protein?
Heart- and neural crest derivatives-expressed protein 2, Class A basic helix-loop-helix protein 26, bHLHa26, Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2, dHAND.
What are the subcellular locations of this protein?
Nucleus.
Protein: AMN_DROME
Sequence: MRSFCCCFYPAAVALHCVLLFYTFFLLFRASALRRRVVSGSKGSAALALCRQFEQLSASRRERAEECRTTQLRYHYHRNGAQSRSLCAAVLCCKRSYIPRPNFSCFSLVFPVGQRFAAARTRFGPTLVASWPLCNDSETKVLTKWPSCSLIGRRSVPRGQPKFSRENPRALSPSLLGEMR
What is the function of this protein?
Required for associative learning and memory in adults.  Expression pattern suggests a modulatory role in memory formation.  Controls neurotransmitter-mediated signaling pathways associated with the structure of the larval peripheral nerve.
What are the official names of this protein?
Amnesiac neuropeptides.
What are the subcellular locations of this protein?
Secreted.
Protein: RSBW_BACAH
Sequence: MMERFEKIEMKIPAKAEYVAIIRLTMAGVANRMGFAYDDIEDMKIAISEACTNIVQHAYKEDVGEIAIVFGLYENRLEIMVADNGVSFDFNNLKRKVGPYDISKPVEHLPENGLGLYLINTLMDDIQIMHDEGMTVLMTKYIQREQVENDGNPISTYESY
What is the function of this protein?
Negative regulator of sigma-B activity.  Phosphorylates and inactivates its specific antagonist protein, RsbV.  Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).
What are the official names of this protein?
Serine-protein kinase RsbW, Anti-sigma-B factor, Sigma-B negative effector RsbW.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-factor family.
Protein: ATPE_BURM9
Sequence: MATIKVDVVSAEEQIFSGQAKFVALPGEAGELGILPGHTPLITRIRPGAVRIESESGDEEFVFVAGGILEVQPGAVTVLADTAIRGKDLDAAKAEEARKRAEETLQNAKSDIDLAKAQSELATAMAQLEAIQRLAKIRGKH
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.