PharMolix/UniProtQA huggingface dataset:
Protein: PDI12_ARATH
Sequence: MAFKGFACFSILLLLSLFVSSIRSEETKEFVLTLDHSNFTETISKHDFIVVEFYAPWCGHCQKLAPEYEKAASELSSHNPPLALAKIDASEEANKEFANEYKIQGFPTLKILRNGGKSVQDYNGPREAEGIVTYLKKQSGPASVEIKSADSATEVVGEKNVVAVGVFPKLSGDEFDSFMALAEKLRADYDFAHTLDAKFLPRGESVEGPAVRLFKPFDELFVDSKDFNGEALEKFVKESSIPLVTVFDSDPNNHPYVAKFFESPATKAMMFVNFTGATAEALKSKYREVATSNKDQSLAFLVGDAESSQGAFQYFGLEESQVPLIIIQTPDNKKYLKVNVEVDQIESWFKDFQDGKVAVHKKSQPIPAENNEPVKVVVAESLDDIVFKSGKNVLIEFYAPWCGHCQKLAPILDEVALSFQNDPSVIIAKLDATANDIPSDTFDVKGFPTIYFRSASGNVVVYEGDRTKEDFINFVEKNSEKKPTSHGEESTKSEEPKKTEETAAKDEL
What is the function of this protein?
Acts as a protein-folding catalyst that interacts with nascent polypeptides to catalyze the formation, isomerization, and reduction or oxidation of disulfide bonds.
What are the official names of this protein?
Protein disulfide isomerase-like 1-2, AtPDIL1-2, Protein disulfide-isomerase 2, PDI 2, Protein disulfide-isomerase 6, AtPDI6.
What is the protein family that this protein belongs to?
Belongs to the protein disulfide isomerase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: CARA_LEPBJ
Sequence: MKAFLVLDNGMILEGESFGYESESVGEIVFNTSMAGYQEILTDPSYCNQIITLTYPMIGNYGIHPDNMESSKIQASGLIVREYVDLPSNFMSQKTLSKFLKEYQIPAIQGIDTRKLTRYIRTNGSPNGGIFVAREYSPEFLEKVKSFPGITGTDLAKVVTTSTKYIFGTHTGKKYKLAVYDYGVKTNILRLLDAAGFAVTVYPALTPAEEIMKEGTDAFFLSNGPGDPAPLDYAIDATRKIMEKGYPLFGICLGHQIIGLSLGKKTEKMKFGHRGGNQPVKNLSTGQVEITSQNHGFAVIDDGKSSEPVSFLNLNDNTVEGILKSGYPLLTVQYHPESAPGPNDSRYLFQKFYDLVETTKRGK
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: OPGG_RHOPA
Sequence: MNRRQVLTGLAALPLLQAKPDPAAADRSSSIDFDPWMVRKLARELASKPYEAPDSSLPASLNDLSYDAYRSLRFRPERALWRAENLPFQVQFFHRGFLYKNRVTIFEVADGKARHVPYRADDFSFGDVAPPPDSDLGFAGFRIHAPLQRADYYDEVSAFLGAAYFRAVTKGERYGLSARGLSIDTGQSSGEEFPLFKTFWLERPAPGASSMVVHALLDSKSVAGAYRFTIRPGDTTVFDVEMALYPRVDLQHAGLAPMTSMFLFGPNDPADTPDFRAAVHDSDGLAIFNGSGEELWRPLCNPKDLQISSFGDRNPRGFGLMQRERSFANYQDLESRYELRPSLWAEPIGDWTDGAVKLIEIPTREEVHDNIASFWEPKQPLRAKGEHIYTYRLHWGPDTPKPKGLARFVRTGVSARGDNDRLFVLDLAGDRLKTVDAAAVRGVVTADKGEIRNIVTQPNPAMGGWRLSFDLAQARAPVELRAVVCEGDAAVSEVWLYRWTP
What is the function of this protein?
Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis protein G.
What is the protein family that this protein belongs to?
Belongs to the OpgD/OpgG family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MIAB_POLAQ
Sequence: MKKLYIKTFGCQMNEYDSGKMADLLHADEGMVMTDTPEDADVVLLNTCSIREKAEDKVFSDLGRLRELKKTKPHMLIGVGGCVASQEGRQIVSRAPYVDVVFGPQTLHRLSDLIAQRRKTGLSQVDISFPEIEKFDHLPASRQTRGSAYVSIMEGCSKYCSYCVVPYTRGEEVSRPFDDVLTEVAGLASKGVKEIVLLGQNVNAYLGKMGDAEEIADFALLIEYIAEIPGVERIRFTTSHPKEFTQRLIDVYAKVPKLVSHLHLPVQHGSDSILSAMKRGYTALEYKSIIRKMRAVRPDLTLSSDFIVGFPGETDADFEKLLKMVQELDFDNSFCFIFSPRPGTPAANLSDDTPYEVKLKRLQTLLALIEGQSNQISQKMLGKTERVLIEGLAKDGVNLQGRAENNRVIHFSPPDQNIDGLIGEMVDIRITEVLNYTLRGELVETHVI
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y202_CLOB8
Sequence: MAIRINNINLSLDDDLNVLEKKICKKLNMSKEDISRLDIIKRSIDARKKNDIKVSFSVNVFCKKEKMLLSRIHDKDISFEEIREIESIKSGTEEIKARPVVVGFGPAGIFAALTLARYGYKPIVYERGEDVDKRTETVEKFWKDGRLNLESNVQFGEGGAGAFSDGKLTTRIKDHRCSFVLDELIKAGAPAEIKYESKAHVGTDLLKGVVKNIREEIKRLGGEVNFNSKLEKITYKDGKLESIVVNGKNITCEALVLAIGHSSRDTYEMLYRENVSMDAKAFAIGVRIEHPQELINVNQYGNNHNHPKLHAADYRLTYQSEKLKRGVYSFCMCPGGVVVAAASEEGRLVSNGMSYHARDLDNANSALVVTVSPEDFKGSSPLRGMEFQRHYESLAFKLGGGNYKAPVQLVGDFMKDRVSTKLGEVIPSYTAGYEFRELKECLPDYVVEALKEGIINFDKKIKGYAREDAILTGIETRTSAPVRLNRNASLESINVCGLYPTGEGAGFAGGIISAAVDGIKVAEHIIEKFDLPK
What are the official names of this protein?
Uncharacterized protein Cbei_0202, ORF1.
Protein: LPP_ECO57
Sequence: MKATKLVLGAVILGSTLLAGCSSNAKIDQLSSDVQTLNAKVDQLSNDVNAMRSDVQAAKDDAARANQRLDNMATKYRK
What is the function of this protein?
A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes.  The only protein known to be covalently linked to the peptidoglycan network (PGN).  Also non-covalently binds the PGN.  The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.
What are the official names of this protein?
Major outer membrane lipoprotein Lpp, Braun lipoprotein, BLP, Murein lipoprotein.
What is the protein family that this protein belongs to?
Belongs to the Lpp family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor; Periplasmic side. Secreted, cell wall; Peptidoglycan-anchor. Note=Attached via its lipidated N- terminus to the inner leaflet of the outer membrane. Attached to the peptidoglycan network (PGN) via its C-terminus.
Protein: HLDD_SALNS
Sequence: MIIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNLVDLNIADYMDKEDFLIQIMSGEELGDIEAIFHEGACSSTTEWDGKYMMDNNYQYSKELLHYCLEREIPFLYASSAATYGGRTSDFIESREYEKPLNVYGYSKFLFDEYVRQILPEANSQIVGFRYFNVYGPREGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVAAVNLWFLESGKSGIFNLGTGRAESFQAVADATLAYHKKGSIEYIPFPDKLKGRYQAFTQADLTNLRNAGYDKPFKTVAEGVTEYMAWLNRDS
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: AROA_ACICJ
Sequence: MEHAATLPQTSRRPATPLTGTITVPGDKSISHRALMFAGLAVGETRISGLLEGEDVLRTAAAMRALGATVERTGPGAWRASGPGIGGLQSPDDVLDMGNSGTAARLLCGILASHDIFAVMTGDASLRRRPMRRVIDPLGATGAVFAAREGGRLPLSVRGAAEAMPLSYRLPVASAQVKSALLLAGLNARGITEIEEPEPTRDHSENMLRHFGAEVEVAAHGTGKLIRLRGQPELRGADVVVPGDPSSAAFPIVAALIVPGSRVTIGGVGLNPLRTGLFLTLREMGAAIEIVNAREAGGEPVGDLIVTASDLRAVDVPAERAPSMIDEYPILAVACAMARGSSRLRGLAELRVKESDRLAATLAMITANGVKAQVDGDDLIIEGGGARGGATVATHMDHRLAMSALVMGLATETPVTIDDARFIDTSFPGFLPLMRGIGAAIEAAA
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSXL9_ARATH
Sequence: MVTFTSEASRSRSKKVCVIGAGPAGLVSARELRKEGHKVVVLEQNEDVGGQWFYQPNVEEEDPLGRSSGSINGELKVHSSIYSSLRLTSPREIMGYSDFPFLAKKGRDMRRFPGHKELWLYLKDFSEAFGLREMIRFNVRVEFVGEKEEEDDVKKWIVRSREKFSGKVMEEIFDAVVVATGHYSHPRLPSIKGMDSWKRKQIHSHVYRVPDPFRNEVVVVVGNSMSGQDISMELVEVAKEVHLSAKTLDISSGLSKVISKHPNLLIHPQIESLEDDGKVIFVDGSWVVADTILYCTGYSYKFPFLESKGRIEVDDDRVGPLFEHTFPPCLSPSLSFVGIPRKLIGFPFFEAQAKWIAQVLSGKSSLPSPDQMLQSVDEFYRSRDLAGVPKHNTHDIADFTYCDKYADYVGFPHLEDWRKLLCLSALNNSQENLETYRDSWDDHELLQEALQSSHFTNFNS
What is the function of this protein?
Catalyzes the conversion of methylthioalkyl glucosinolates of any chain length into methylsulfinylalkyl glucosinolates.
What are the official names of this protein?
Flavin-containing monooxygenase FMO GS-OX-like 9, Flavin-monooxygenase glucosinolate S-oxygenase-like 9.
What is the protein family that this protein belongs to?
Belongs to the FMO family.
Protein: FAR19_LUCCU
Sequence: SANAKNDFMRF
What are the official names of this protein?
FMRFamide-19, LucFMRFamide-19.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL21_CLOB8
Sequence: MYAVLATGGKQYRVQEGDVIYVEKLNADVDSTVELNEVLAVGTEEGIKVGAPVVEGAKVVAKVAAQGKAKKVVVFKYKSKKDYRRKNGHRQPYTKLVIEKIEA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: AROB_SHESA
Sequence: MTKQIQVDLGERSYPIYIGQSLMSDGETLSRYLLKKRILIVTNETVAPLYLKQIQDTMASFGEVTSVILPDGEQFKDLTHLDSIFTALLQRNYGRDSVLVALGGGVIGDMTGFAAACYQRGVDFIQIPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPQIVIIDTECLQTLPAREFAAGMAEVIKYGIMWDAEFFQWLENNVQALKSLDTQALVYAISRCCEIKADVVSQDETEQGVRALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGTVLAAQTAKSMGLIDESIVRRIVQLFHAFDLPVTAPESMDFDSFIKHMRRDKKVLGGQIRLVLPTAIGRADVFSQVPESTLEQVICCA
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_UREU1
Sequence: MNRIKKGDTVVVISGKNKNKSGVVIQVNPKEQTALVEGVNKIKRHQKKDQTHEQSGIIEKEAPIRLCKLALVDPKGKDKGKATKVKYLLKDNKKVRVARKSGSELDANKK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: GPR39_HUMAN
Sequence: MASPSLPGSDCSQIIDHSHVPEFEVATWIKITLILVYLIIFVMGLLGNSATIRVTQVLQKKGYLQKEVTDHMVSLACSDILVFLIGMPMEFYSIIWNPLTTSSYTLSCKLHTFLFEACSYATLLHVLTLSFERYIAICHPFRYKAVSGPCQVKLLIGFVWVTSALVALPLLFAMGTEYPLVNVPSHRGLTCNRSSTRHHEQPETSNMSICTNLSSRWTVFQSSIFGAFVVYLVVLLSVAFMCWNMMQVLMKSQKGSLAGGTRPPQLRKSESEESRTARRQTIIFLRLIVVTLAVCWMPNQIRRIMAAAKPKHDWTRSYFRAYMILLPFSETFFYLSSVINPLLYTVSSQQFRRVFVQVLCCRLSLQHANHEKRLRVHAHSTTDSARFVQRPLLFASRRQSSARRTEKIFLSTFQSEAEPQSKSQSLSLESLEPNSGAKPANSAAENGFQEHEV
What is the function of this protein?
Zn(2+) acts as an agonist.  This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.  Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins.  Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death (By similarity).
What are the official names of this protein?
G-protein coupled receptor 39.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PURA1_MOUSE
Sequence: MSGTRASNDRPPGTGGVKRGRLQQEAAATGSRVTVVLGAQWGDEGKGKVVDLLATDADIVSRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAEKNEKKGLKDWEKRLIISDRAHLVFDFHQAVDGLQEVQRQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLSDFDEFSARFKNLAHQHQSMFPTLEIDVEGQLKRLKGFAERIRPMVRDGVYFMYEALHGPPKKVLVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIGAFPTEQINEIGDLLQNRGHEWGVTTGRKRRCGWLDLMILRYAHMVNGFTALALTKLDILDVLSEIKVGISYKLNGKRIPYFPANQEILQKVEVEYETLPGWKADTTGARKWEDLPPQAQSYVRFVENHMGVAVKWVGVGKSRESMIQLF
What is the function of this protein?
Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase isozyme 1, AMPSase 1, AdSS 1, Adenylosuccinate synthetase like 1, Adenylosuccinate synthetase, basic isozyme, Adenylosuccinate synthetase, muscle isozyme, M-type adenylosuccinate synthetase, IMP--aspartate ligase 1.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein. Note=Partially associated with particulate fractions.
Protein: PEPT_MACCJ
Sequence: MKEKLIDRLTSYVVIDTQSDASSTTTPSTDKQWNLLNQLKQEIEQLGLETDIDEYGYLFATLPSNTNKDVPVIGLLAHVDTATDFTGTNVNPQIIQSYDGNDITLKSGLKIETAKFPELSLYKGHTLITTDGTTLLGADNKAGIAEIMTAIEYLIAHPEIKHGKIRFGFTPDEEIGRGPHKFDVERFACDFAYTIDGGRRGELQYESFNAAGVNVTFNGVNVHPGSAKDKMVNALNLAVRFQSSLPANEVPEHTEGYEGFFHLMELNGNVERAQLSYIIRDHSREQFEARKVKMHEIITSIQNEYGEQAAHIEINDQYYNMGEKITPHPQLIDIPLEVMKSLNIEPIVEPIRGGTDGSQLSYMGLPTPNLFTGGENYHGPYEYVSVDDMERAVMNIVGILQKFEEKA
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_RHIRD
Sequence: MAREYKIEDYRNFGIMAHIDAGKTTTTERILYYTGKSHKIGEVHDGAATMDWMEQEQERGITITTAATTTFWKGRDGKMRRFNIIDTPGHVDFTIEVERSLRVLDGAIALLDANAGVEPQTETVWRQAEKYNVPRMIFCNKMDKTGADFYRSVEMIKTRLGATAVVMQLPIGAETEFKGVIDLIEMNALIWRDESLGAQWDVVEIPDDLKAKADEYREKLIETVVEIDEEAMEDYLNGIMPDNDKIRALVRRGTIDVKFLPMFCGTAFKNKGVQPLLDAVVDYLPSPLDIPAIKGIDFKTEAEIERHADDSEPLSMLAFKIMNDPFVGSLTFARIYSGKLEKGTSVINTVKDKREAVGRMLQMHSNSREDIEEAFAGDIVALAGHKETTTGDTLCDPLKPVILERMEFPEPVIQIAIEPKTKGDQEKMGLALNRRAAEDPSFRVKTDEESGQTYYAGMGELHLDILVDRMRREFKVEATVGAPQVAYRETITRHDEEDYTHKKQSGGTGQFARVKIIFEPNPEGEDFKFESKIVGGAVPKEYIPGVQKGIESVLSSGPLAGFPMLGVKATLIDGAYHDVDSSVLAFEIASRACFREAAKKAGAQLLEPMMKVEVVTPEDYVGDVIGDLNSRRGQIQGQESRGITIVISAHVPLANMFKYVDNLRSMSQGRAQYSMTFDHYSPVPSNVAQEIQAKYSGQK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA_RALPJ
Sequence: MSTPSRSAALFERAQKTIPGGVNSPVRAFRSVGGIPRFIAKAAGPYLWDADGTRYIDYVGSWGPMIVGHAHPEVVRAVQEVAADSFSFGAPTEAEVVMAEEICKLVPSIEQVRLVSSGTEATMSALRLARGFTGRDLIVKFEGCYHGHADSLLVKAGSGLLTFADTTQNAPSSTGVPEDVVKHTMVLPYNDVAALREAFARHGKEIAAVIVEPVAGNMNLVRGSNEFHQAMRALCTEHGAVLIFDEVMTGFRVALGCAQALYGIKPDLTCLGKVIGGGMPAAAFGGRRDIMGFLAPLGSVYQAGTLSGNPLAVAAGLTTLRLIAAEGFHDRLATQTRKLVDGLAEIAREVGVPFAADSVGGMFGIYFREGVPTSFAEVTKSDVGRFNAFFHAMLDQGVYLAPSAFEAGFVSSTHDDAILDATFEAARKAFKAV
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IMND1_ENTGE
Sequence: MTPTIITDVKSFAIKPDRHNLVVVKVETNKGISGLGCSTFQFRPLAVKTVVDEYLRPLLMGRDANEIEDIWQVMNVNSYWRNGPITNNAISGIDMALWDIKGQLADMPLYQLLGGKARTAIPAYTHAVADNLDDLYHEIDRFLAAGYRYIRCQLGFYGGNPSQLQTPEEPISGSYFDQTDYMETTLKMFAAIKEKYGNQFQMLHDVHERLHPNQAIQFAKAAEPYQLFFLEDILPPDQSHWLTQLRSQSATPIATGELFNNPMEWQELVKNRQIDFMRAHVSQIGGITPALKLAHFCDAMGVRIAWHTPSDISPVGLAVNTHLNIHLHNAAIQETIELPANTQSVFVGSPQPKGGFFYPMEKSGIGITFDEEAAADFPVVYRPHEWTQSRTPDGTLITP
What is the function of this protein?
Has no detectable activity with D-mannonate and with a panel of 70 other acid sugars (in vitro), in spite of the conservation of the residues that are expected to be important for catalytic activity and cofactor binding.  May have evolved a divergent function.
What are the official names of this protein?
D-galactonate dehydratase family member EGBG_01401.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
Protein: FOLD_JANSC
Sequence: MTEPQTNRTSGAKIIDGKAFAADVRGQVAGHVQRLKDEHGITPGLAVVLVGEDPASEVYVSHKHKATVEVGMTSFEHKLPADTSEDDLFALIDKLNADPAVHGILCQFPVPDHLDERRTVARISPAKDVDGLSVTNAGLLSSGGEALVSCTPLGCLMLLRAEFDSLSGKDAVVIGRSNLFGKPMAQLLLGDNCTVTIAHSRTKDLADVCRRADILVAAVGRAEMVRGDWIKPGATVIDVGISRVPHPDKPGKTKLIGDVHFAEAVDVAGAITPVPGGVGPMTIACLLANTVTACCRAHGLDEPRGLTA
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: KRT34_HUMAN
Sequence: MLYAKPPPTINGIKGLQRKERLKPAHIHLQQLTCFSITCSSTMSYSCCLPSLGCRTSCSSRPCVPPSCHGYTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELEKLIQERSQQQEPLLCPSYQSYFKTIEELQQKILCAKAENARLVVNIDNAKLASDDFRSKYQTEQSLRLLVESDINSIRRILDELTLCKSDLESQVESLREELICLKKNHEEEVNTLRSQLGDRLNVEVDTAPTVDLNQVLNETRSQYEALVEINRREVEQWFATQTEELNKQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEAHYSSQLSQVQSLITNVESQLAEIRCDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCKLPCNPCATTNASGNSCGPCGTSQKGCCN
What are the official names of this protein?
Keratin, type I cuticular Ha4, Hair keratin, type I Ha4, Keratin-34, K34.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: ISOC2_BOVIN
Sequence: MAAARPALGRVLPGSSMLFLCDMQEKFRHVVYFRQIVSMAARMLKVARLLSVPTVLTEQYPQGLGPTVPELGAQGLQPYSKTCFSMVPAVQQELDARPQLRSVLLCGVETQACILQTALDLLDRGLQVHVVVDACTSRSQVDRLVALSRLRQSGAFLSTSEGLIFQLVGDATHPQFKEIQKLVKEPSPDSGLLGLFQDQNPLFR
What are the official names of this protein?
Isochorismatase domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the isochorismatase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes to the nucleus in the presence of CDKN2A.
Protein: GLO2_DECAR
Sequence: MLEISFIPAFKDNYIWLLTRGKRAFVVDPGDAAPVLARLEAGGLMLEGILITHHHADHQGGVAELKARWQAEVYAPGNESITGCSCPLSGGESIDVLGQKVTVMAVPGHTLGHLAYYAPGALLCGDTLFGAGCGRLFEGTPAQMSASLDSIAALPGDTLIYCAHEYTEMNLRFALAVEPNNQALQARVAKVAALRAAGLPSVPLILAEEKATNPFLRCHEAAVVEAGLQHAASCLLGHAAQQGADIEDRSKTAIFAAIRSWRNTF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: GSPL_PSEAE
Sequence: MSGVSALFLPPASTAGADGELAVWWVQDGECRRAPFAQALAEIRAPWRLYLPVEAVTACAVNLPTQKARWLRQSLPFAVEEQLADDVEQMHLALGPALADGRHRVFAVQRTWLAAWLALAEGAGKAPASLHVDADCLPGEGSCLFWLEERWLLGGSGAVRLACGSEDWPVLRDSCPPPQRAFAAQEVAPLEGVEVQALAGNPHVWLSEQPLGTDLAQAEFAARQQSSQWRRWRPLLGLVGLWLVLQWGFTLVQAWQLQREGDRYAAQSAELYRQLFPEDRKLINLRAQFDQHLADSASSGGEGQLLGLLGQAATVIGGEPTVSVEQLDFSAARGDVALQVRAPGFDVLERLRSRLSESGLAVQLGSASRDGSTVSARLVIGG
What is the function of this protein?
Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.  Plays a role in the complex assembly and recruits XcpZ resulting in a stable complex in the inner membrane.  Provides thus a link between the energy-providing XcpR protein in the cytoplasm and the rest of the T2SS machinery.
What are the official names of this protein?
Type II secretion system protein L, T2SS protein L, General secretion pathway protein L.
What is the protein family that this protein belongs to?
Belongs to the GSP L family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PSBL_PINTH
Sequence: MTRPNPNDQNVELNRTSLYWGLLLIFVLAVPFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RL24_CHLAD
Sequence: MHVKTGDEVLVIAGKDKGRRGKIKRALPAVNRVVVEGLNIVKRHQKPRGPGRPGGIVEMEAPIHVSNVMLICPSCGRASRTGKRFLEETDHKGRPRKVRYCKACDAIIDK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: AUAH_STIAU
Sequence: MRTFVTGGSGYLGRNLLSALVARGISVRALVRSEEAAQKVQALGAQPILGTLEHRETLKEGMAGCDVLFHAAALTSARATDAEFHRANVLGTETVLAAARDARIQRMVHVSTEAVLADGRPLLQVDESHPLPKRPFAGYPATKAQAEQLVLQANGPGFTTVVVRPRFIWGADDTAFLPQLIDAIRTKRFRWVDGGRYLTSTCHVANVCEGMLLAAERGPGGEVYFLTDGAPVELRSFLTLLLETQGIKAEVGNIPFQAARAAAHLGESLWRALVPQARAPALRLAVYLLGREVTLNDDKARRELGYAGRVTHQQGLDALRQAGPAGQGAMPHRA
What is the function of this protein?
Catalyzes the final step in the conversion of aurachin C to aurachin B.  Catalyzes the reduction of 4-hydroxy-2-methyl-3-oxo-4-((2E,6E)-farnesyl)-3,4-dihydroquinoline-1-oxide to form 2-methyl-1-oxo-4-((2E,6E)-farnesyl)-3,4-dihydroquinoline-3,4-diol, which then undergoes a spontaneous dehydration to form aurachin B.  Accepts both NADH and NADPH, but has a preference for NADH.
What are the official names of this protein?
Aurachin B dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the 3-beta-HSD family.
Protein: FABZ_ZYMMO
Sequence: MTETTEKVESIGPLDVKRVMAALPHRFPMLLVDRVETLIPGEKIVAIKAVTINEPFFTGHFPGNPIMPGVLIVEALAQAAGVLAIESLGLTGTGKLVYFMAINETKFRIPVEPGILLRLEVEFLQKRAKICKFKARALIEDKVAAETEFTAMIADPAN
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.