PharMolix/UniProtQA huggingface dataset:
Protein: SYN3_MOUSE
Sequence: MNFLRRRLSDSSFVANLPNGYMPDLQRPESSSSSPASPATERRHPQPLAASFSSPGSSLFSSFSGAMKQTPQAPSGLMEPPTPVTPVVQRPRILLVIDDAHTDWSKYFHGKKVNGDIEIRVEQAEFSELNLAAYVTGGCMVDMQVVRNGTKIVRSFKPDFILVRQHAYSMALAEDYRSLVIGLQYGGLPAVNSLYSVYNFCSKPWVFSQLIKIFHSLGPEKFPLVEQTFFPNHKPMLTAPNFPVVIKLGHAHAGMGKIKVENQHDYQDITSVVAMAKTYATTEAFIDSKYDIRIQKIGSNYKAYMRTSISGNWKANTGSAMLEQVAMTERYRLWVDSCSEMFGGLDICAVKAVHSKDGRDYIIEVMDSSMPLIGEHVEEDKQLMADLVVSKMSQLLVPGATVPSPLRPWGPQTKPAKSPGQGQLGPLLGQPQPRPPPQGGPRQAQSPQPPRSRSPSQQRLSPQGQQPVSPQSGSPQQQRSPGSPQLSRASGGSSPNQASKPSASLSSHNRPPVQGRSTSQQGEEPQKSASPHPHLNKSQSLTNSLSTSDTSHRGTPSEDEAKAETIRNLRKSFASLFSD
What is the function of this protein?
May be involved in the regulation of neurotransmitter release and synaptogenesis.  Binds ATP with high affinity and ADP with a lower affinity.  This is consistent with a catalytic role of the C-domain in which ADP would be dissociated by cellular ATP after bound ATP was hydrolyzed (By similarity).
What are the official names of this protein?
Synapsin-3, Synapsin III.
What is the protein family that this protein belongs to?
Belongs to the synapsin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Peripheral membrane protein localized to the cytoplasmic surface of synaptic vesicles.
Protein: GLGB2_XANAC
Sequence: MSQTLQALADGLPADAFAVLGPKLLADGRRQVRVLAPGAEAMGLIDPRGKLLARMQASAIDGVFEGTLAVDGPYRLRIVWPDRVQEVEDPYAFAATLDESLLLQIAAGDGQALRRALGAQHLHCGDVPGVRFALWAPHAQRVAVVGDFNGWDVRRHPMRQRIGGFWELFLPRVDAGARYKYAVTAADGRVLLKADPVARQTELPPATASVVPSAATFAWTDAAWMANRDPAAVPGPLSIYEVHAASWRRDGHNQPLDWPTLAEQLIPYVQQLGFTHIELLPITEHPFGGSWGYQPLGLYAPTARHGSPDGFAQFVDACHRAGIGVILDWVSAHFPDDAHGLAQFDGAALYEHADPREGMHRDWNTLIYNYGRPEVTAYLLGSALEWIEHYHLDGLRVDAVASMLYRDYGRAEGEWVPNAHGGRENLEAVAFLRQLNRDIATQFPGVLTIAEESTAWPGVTAAISDGGLGFTHKWNMGWMHDTLGYMQRDPAERAHHHSQLTFGLVYAFDERFVLPLSHDEVVHGTGGLLGQMPGDDWRRFANLRAYLALMWAHPGDKLLFMGAEFGQWADWNHDQSLDWHLLDGARHRGMQQLVGDLNAALRRTPALYRGTHRAEGFDWSVADDARNSVLAFVRHDPDGGAPLLAVSNLTPQPHHDYHVGVPRAGLWREILNTDSAHYGGSNLGNSGRLATEPVGMHGHAQRLRLTLPPLATIYLQAEK
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB 2, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase 2, Alpha-(1->4)-glucan branching enzyme 2, Glycogen branching enzyme 2, BE 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: SMG_SHEON
Sequence: MFDILMYLFENYVHSEVELLVDEDELTKELTRAGFHQSEILKALTWLERLAELQEGDKPYLCNHDQHSFRIYTKDEMEKLDVECRGFLLFLEQVKVLNVETREMVIDRVMELDEPALILEDLKWVILMVLFNAPGHESAYEQMEDLIFEQPEEGRLHS
What are the official names of this protein?
Protein Smg homolog.
What is the protein family that this protein belongs to?
Belongs to the Smg family.
Protein: GLNA3_PEA
Sequence: MSSLSDLINFNLSDSTEKIIAEYIWVGGSGIDIRSKARTLPGPVSDPAKLPKWNYDGSSTNQAPGKDSEVILYPQAIFKDPFRRGNNILVICDVYTPAGEPLPTNKRYNAAKIFSHPDVAAEVPWYGIEQEYTLLQKDINWPLGWPIGGYPGKQGPYYCGIGADKAYGRDIVDAHYKACLFAGINISGINGEVMPGQWEFQVGPSVGISAGDEIWAARYILERITEIAGVVVSFDPKPIPGDWNGAGAHANFSTKSMRENGGYEVIKKAIEKLGLRHKEHIAAYGEGNERRLTGKHETADINVFSWGVANRGSSIRVGRDTEKDGKGYFEDRRPASNMDPYVVTSMIAETTILWKKP
What are the official names of this protein?
Glutamine synthetase root isozyme A, Cytosolic GS3 A, Glutamate--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIR1_YEAST
Sequence: MSGVNNTSANDLSTTESNSNSAVGAPSVKTEHGDSKDSLNLDATEAPIDLPQKPLSAYTTVAILCLMIAFGGFIFGWDTGTISGFVNLSDFIRRFGQKKTTRGLTTYRK
What is the function of this protein?
Probable glucose transporter.
What are the official names of this protein?
Putative transporter-like protein YIL171W.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RLMD_METFK
Sequence: MSTPIALVESLDQEGRGVAHVEGKTIFIDGALPGEQVTYKVRRRKERYEVADVLDVLQASHLRTQPGCEHFGVCGGCAIQHLEFSGQVAAKQRMLESNLWHIGKTRSERMLPPIYGPAWGYRHKARLRVRHVAKKGGVLVGFNEKSSSFVADMDSCRVLPPHVSNLIVPMKELVGQLSIRDRLPQIEVAVGELATVLVLRILEPLQPQDAAPIKAFADRYGVEVWTQSKGPDTVQPFYPLQGPGLSYSLPEFNLTYPFKPTEFTQVNPYINRVMLRRAMQLLQPQPGERIADFFCGLGNFTLPIARSGASVFGMEGSAALVARANESAALNSLAGQVEFQEADLFKMTPALLQSLGRFDKWLIDPPRDGAIELVKALPDIEDADADTSHVPQRIVYVSCNPATLARDAGILVHTKGYRLLASGVINMFPHTSHVESIALFEKASP
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: SPC25_GIBZE
Sequence: MATDFRSSFSASMRQSMPPVGPSVANQLPNINFGFDDLRDRMAKFTARFDAFIEEGRKRVLDERNQFRMNVAELQEDQRMKKRDIEIVQTKTATHQQTIEKEKAETREMETAINSLASQRDNHLSTRDSLKAEIAQTQAEIETRLAAQREYAQHQQSQSRFNVPELDFWITNLCLKIEGAGHDDRLKFVYTHVDEKDWEREAWFELVTSSRDYDVKHCRPKVEREKVEKVLDKLNESRELVVLLKGMRELFVEAMKS
What is the function of this protein?
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
What are the official names of this protein?
Probable kinetochore protein SPC25.
What is the protein family that this protein belongs to?
Belongs to the SPC25 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with kinetochores.
Protein: PMF1_MOUSE
Sequence: MAEVSRDSEAAERGPEGSSPEAVPGDATIPRVKLLDAIVDTFLQKLVADRSYERFTTCYKHFHQLNPEVTQRIYDKFVAQLQTSIREEISEIKEEGNLEAVLNSLDKIIEEGRERGEPAWRPSGIPEKDLCSVMAPYFLKQQDTLCHQVRKQEAKNQELADAVLAGRRQVEELQQQVRALQQTWQALHREQRELLSVLRAPE
What is the function of this protein?
Part of the MIS12 complex which is required for normal chromosome alignment and segregation and for kinetochore formation during mitosis (By similarity).  May act as a cotranscription partner of NFE2L2 involved in regulation of polyamine-induced transcription of SSAT.
What are the official names of this protein?
Polyamine-modulated factor 1, PMF-1.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with the kinetochore.
Protein: RL29_PROM4
Sequence: MARPEISEVTKLTDDDLKNKIDEIRKELFDLRFKRATRQLSETHRFKEARIQLAQLLTVQGDRNRSKTSS
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: F16PA_NEIM0
Sequence: MDTLTRFLPEHLQQNQLPEALGGVLLSVVSACTEINAKVRLGALAGVLGMTGTGNIQGEDQKKLDVIANNIMIDTLKANPAVAGLASEEEDTFVSAGENGRYLVLFDPLDGSSNIDVNISVGTIFSILEKPEGALATESFLQTGRQQLAAGYVLYGPQTQLVFTFGHGVYMFTLNAENEFVLTKEKPKVPESTKEFAINMSNRRHWLPPVQQYIDELLAGETGTRGKNYNMRWVASMVAEIHRILMRGGVFMYPQDKRDPAKPGKLRLMYEANPMSLILEQAGASASNAYQAMLDIQPENLHQRVAVFMGSSEEVDYLNRLHSK
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA_LEPIC
Sequence: MIAKSGSNQESNPMFQGVYTAIITPFKNDKIDYDSYFKLLEKQIKAGVSGVVPCGTTGESPTLSHSEHAELIRETVKAVQGKIQVVAGTGSNSTKEAIELTEAACKDGVDGILSVNPYYNKPTQEGLFQHFKSIAEHSTVPVMLYNIPGRTSVNLLPETVLRLSEVKQIRSMKEATGDLGQMGKLISLVGNKMTVLSGDDNLTLPLLAIGGVGVVSVISNLFPKALVQLVESFQQGKISEAKKIHYDFIEVFALAFMETNPIPIKAAMCWFGHCGPEIRLPLTPLSQNETSSKFKKVLEGLKEKGYE
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN750_DANRE
Sequence: METLQGRKPKKPHYIPRPPGKPFKYQCFQCPFTCNIKSHLFNHMKYNLCKNSISLVSQRMEQTGKASRASQHSPAFSHNSKELPLDAESTKPIENVKIEKAVTKEAREKPQSPIKEVSKDDTEPALEAKDKSEDMDIAQNKISSAFSPVARTCESEALSLSPHKDDQSTIPHFYQQIAPWVTSASSAHLLPPIPEYPPYMVPERSLPPLYAPYPHNQASTPAYQVTPRETQRPLVPSPLIPPNSSLLHPYHYRYGHSIFPSPPLPYSFYQHPELSIPLQRSRYLPLDVYSSRFYPREYGGHLVPLTHPESYSRLAEDRAVQEHNTGDKGIRESPLEGCDASGSPDRPSTADVTQRIPVGLRLASHGESHSGSQSHIISGSTKANDNLPKMPCGQNQEKMLQKTERYDSQTTISSRSSDISDKEEDEETEEEIGPLNLSKRDQATSNNMTHHHYPDRELHYDSESSQEEAPLNLCLRVQSSNQALPNTSETPEKETISNAEVSTTESPQDLEPCDQRQTAAFALCQLASSRDIINDTSVKQQDVTESQNTKCLPSPDNCSVKDSPNILNASMVALGQKRANNRPLRHTNKRAKVKEPSRPRRKRSQNC
What is the function of this protein?
Transcription factor involved in epidermis differentiation.
What are the official names of this protein?
Zinc finger protein 750.
What are the subcellular locations of this protein?
Nucleus.
Protein: NUOC_MYCBO
Sequence: MSPPNQDAQEGRPDSPTAEVVDVRRGMFGVSGTGDTSGYGRLVRQVVLPGSSPRPYGGYFDDIVDRLAEALRHERVEFEDAVEKVVVYRDELTLHVRRDLLPRVAQRLRDEPELRFELCLGVSGVHYPHETGRELHAVYPLQSITHNRRLRLEVSAPDSDPHIPSLFAIYPTNDWHERETYDFFGIIFDGHPALTRIEMPDDWQGHPQRKDYPLGGIPVEYKGAQIPPPDERRGYN
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: COMT_BOVIN
Sequence: MLEAPPLLLVAGGVGLALLALRWLATTDLQFFGRAFIVWNEFIMKPIRNLLMGSSKEQRILQHVLQHAVAGDPQSVVAAIDSYSLEKEWAMHVGEKKGQIVDRVLREQQPSVLLELGAYCGYSAVRMARLLLPGARLLTIEFNPDYAAITQRMVEFAGLQDKVTVVLGASQDIIPQLKKKYDVDTLDMVFLDHWKDRYLPDMLLLEECGLLREGTVLLADNVIYPGAPDFLEYVRGNSRFECSHFSSYLEYSKVVDGLEKVVYKGLSGPARP
What is the function of this protein?
Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.  Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol.
What are the official names of this protein?
Catechol O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
What are the subcellular locations of this protein?
[Isoform Soluble]: Cytoplasm. SUBCELLULAR LOCATION: [Isoform Membrane-bound]: Cell membrane; Single-pass type II membrane protein; Extracellular side.
Protein: RS18_CANLF
Sequence: MSLVIPEKFQHILRVLNTNIDGRRKIAFAITAIKGVGRRYAHVVLRKADIDLTKRAGELTEDEVERVITIMQNPRQYKIPDWFLNRQKDVKDGKYSQVLANGLDNKLREDLERLKKIRAHRGLRHFWGLRVRGQHTKTTGRRGRTVGVSKKK
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
40S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_ANADF
Sequence: MMPTKPLAEADPQIAQLIREETRRQAEGLELIASENFVSPAVMEAMGSTLTNKYAEGYPGKRYYGGCEVVDKVEQLAIDRAKQLFGAEHANVQPHSGSQANMAAYFALATPGDTVLAMSLNFGGHLTHGSPVNFSGKLFKIVPYGLKQSDETIDMDEVARLAREHRPKVLMVGASAYPRTLHFDRFAGIAREVGAALVVDMAHIAGLVAAGLHPNPVPHAEIVTTTTHKTLRGPRGGLILTREAHAKVLNSQIFPGIQGGPLEHVIAAKAVAFHEALQPSFKEYQRRIVENAQALAEGLKEAGLRLVSGGTDNHLMLVDLRPKKLTGKIGEEALGKAGITVNKNMIPWDPEKPMTTSGIRVGTPALTTRGMGPGEMATVASLIGRVLDAPADEKVIAAVRGEVRELCAQFPMYQDRL
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTL26_BOVIN
Sequence: MLVAEAAERNKEPILQVLRQYLDSAQRGVRVLEVASGSGQHIAHFARAFPHAEWQPSDVDQRCLDSILATTQAHGLPNVKAPMYLDVTWDWKQWGGILPQSLDLLVCINMSHISPLSCTEGLFRAAGHLLKPKAVLITYGAYAINGKISPQSNVDFDLTLRCRNPEWGLRDTSLLKDLGQASGLLLERMVDMPANNKCLIFRKQ
What are the official names of this protein?
Methyltransferase-like 26.
What is the protein family that this protein belongs to?
Belongs to the UPF0585 family.
Protein: SFSA_TRIEI
Sequence: MICYPIIMNNQLKFSYKYPSLEPGILIKRYKRFLADIELKSGGIITAHCPNTGPMTGVSTPGSNVMVSYSNNPKRKLAYTWELIEVTDNEPTWVGINTALPNRVIKLALAENLFPELGDYYEVKTEVVYGKDRKSRVDFKLISETKNIYLEVKNTTWADGRVALFPDTVTKRGQKHLRELIGVVEQGERAVCLFLINRGDCYQFAPGDVADHDYGKLLREAMIKGVEILPCRFIVTPQEINYLGIAEFIN
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: TRUA_VIBCH
Sequence: MRIALGIEYDGTHYYGWQRQREVKSVQEALEKALSKIANHPVEVQCAGRTDAGVHGTGQVVHFDTTAERQMVAWTMGANANLPKDIAVRWAMAVPDEFHARFSATARRYRYVIYNHVYRPGILNSGVSHYHGELDVEKMQQAGQYLLGENDFTSFRAVHCQSRSPWRNVMHLNVTRHGRYVVIDIKANAFVHHMVRNITGSLIAVGRGEQKPEWIQWLLAQKDRTLAAATAKAEGLYLVSVDYPAHFGLPEMPIGPLFLPDNLN
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: RUVA_KLEP7
Sequence: MIGRLRGIILEKQPPLVLLETAGVGYEVHMPMTCFYELPEAGQEAIVFTHFVVREDAQLLYGFNNKQERTLFKELIKTNGVGPKLALAILSGMSAQQFVNAVEREEVASLVKLPGIGKKTAERLIVEMKDRFKGLHGDLFTPAADLVLTSPAGPTADDAEQEAVAALVALGYKPQEASRMVSKIARPDANSETLIREALRAAL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: FABZ_RHORT
Sequence: MQADPQENQVRTTVDIARIIDMIPHRYPFLMVDKLIDMVRGESAIGIKNVTINEPFFQGHFPNRPVMPGVLIVEAMAQTAAVLVVETLGVRAEGKIVYFMIVENARFRKPVIPGDQLRLHVAKERHRGNVWKFRGVAKVDEVVVAEATFAAMIMDEEPQP
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABH_RICFE
Sequence: MTCKIIGSGGYLPSKIVSNDELAKFVDTNDEWIRTRTGITQRHIAGDTEYTSHLALKSAEKAIADARVSVNDIDLIITCTTTPDNSFPSVASKLQGYLGLTNIPSFDLQAVCAGFVYGLQVANSLIASGKYKTVLLIGAEKMTSLLDWSDRSTCVLFGDGAGSVILQRSSDDSGLIDSNIFSSGADYEILYTNGGVSMNGISGKIVMQGQKLFRHAIEKMQQSIEDLLHANQFSVSDIDYFIPHQANIRIINKLAELLNIEEHKVVKTVEKHANCSAASIPLALSTLKASGKIKKGDILLFSAIGAGLTWGSALIRW
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NARL_MYCTU
Sequence: MSNPQPEKVRVVVGDDHPLFREGVVRALSLSGSVNVVGEADDGAAALELIKAHLPDVALLDYRMPGMDGAQVAAAVRSYELPTRVLLISAHDEPAIVYQALQQGAAGFLLKDSTRTEIVKAVLDCAKGRDVVAPSLVGGLAGEIRQRAAPVAPVLSAREREVLNRIACGQSIPAIAAELYVAPSTVKTHVQRLYEKLGVSDRAAAVAEAMRQRLLD
What is the function of this protein?
Member of the two-component regulatory system NarS/NarL that regulates genes involved in aerobic nitrate metabolism (PubMed:25659431).  Upon phosphorylation by NarS, functions as a transcription regulator by direct binding to promoter regions of target genes together with DevR to regulate their expression during aerobic nitrate metabolism (PubMed:25659431).
What are the official names of this protein?
Probable transcriptional regulatory protein NarL.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTL_HERAR
Sequence: MHASSPSVRPIQALSDQLISQIAAGEVVERPSAVVKELLENALDAGATHISVRLEQGGVKRIAITDNGRGIAPEQLPLALARHATSKINSLTELENVATLGFRGEALASIASVSQLTLTSRTADAAHAWEISGVQSIDQKSTVAPSSGTAGTTVDVLDLYFNTPARRKFLKTEQTEFGHCAEVVRRIALSRPDVAFSLTHNGKTIDHWAVNDIARRSAHILGNEFSAARLPLKETAGPLRLHGFIGLPTASKARGDAQYFYVNGRFVRDKLLMHAVRSAYQDVLHGDRYPSYVISLELDPALVDVNVHPSKIEVRFRDSRAVHQFVFHAVTRALAQTSATAFGAAPSPTPAPSSALPWLREQQQSTFAPQFNSPYGVAQSAANYGALFANGPASNDSNSAAPSLHTAGSHGATTLPDDEFPLGFALAQLHGIFILAQNTKGLVLVDMHAAHERILYEQLKHALDDNELQVQPLLIPITFYADGMEVGTTEDNQDILHALGFDIAALSPTTLAVRAVPALLKNADAQTLARDVLRDVREFGGSRVLLERRNELLGTLACHTAVRANRTLTVPEMNALLRQMEATERADQCNHGRPTWVQLGLSDLDKLFERGR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: XYLA_SHISS
Sequence: MQAYFDQLDRVRYEGSKSSNPLAFRHYNPDELVLGKRMEEHLRFAACYWHTFCWNGADMFGVGAFNRPWQQPGEALALAKRKADVAFEFFHKLHVPFYCFHDVDVSPEGASLKEYINNFAQMVDVLAAKQEESGVKLLWGTANCFTNPRYGAGAATNPDPEVFSWAATQVVTAMEATHKLGGENYVLWGGREGYETLLNTDLRQEREQLGRFMQMVVEHKHKIGFQGTLLIEPKPQEPTKHQYDYDAATVYGFLKQFGLEKEIKLNIEANHATLAGHSFHHEIATAIALGLFGSVDANRGDAQLGWDTDQFPNSVEENALVMYEILKAGGFTTGGLNFDAKVRRQSTDKYDLFYGHIGAMDTMALALKIAARMIEDGELDKRIAQRYSGWNSELGQQILKGQMSLADLAKYAQEHNLSPVHQSGRQEQLENLVNHYLFDK
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FADA_ESCF3
Sequence: MEQVVIVDAIRTPMGRSKGGAFRNVRAEDLSAHLMRSLLARNPALEAAALDDIYWGCVQQTLEQGFNIARNAALLAEVPHSVPAVTVNRLCGSSMQALHDAARMIMTGDAQACLVGGVEHMGHVPMSHGVDFHPGLSRNVAKAAGMMGLTAEMLARMHGISREMQDAFAARSHARAWAATQSGAFKNEIIPTGGHDADGVLKQFNYDEVIRPETTMEALATLRPAFDPVSGTVTAGSSSALSDGAAAMLVMSESRARELGLKPRARVRSMAVVGCDPSIMGYGPVPASKLALKKAGLSASDIGVFEMNEAFAAQILPCIKDLGLMEQIDEKINLNGGAIALGHPLGCSGARISTTLLNLMERKDVQFGLATMCIGLGQGIATVFERV
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, Acetyl-CoA acyltransferase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BETA_STAES
Sequence: MRRKRDSYDYVIIGGGSAGSVLGARLSEDKDKNVLVLEAGRSDYFWDLFIQMPAALMFPSGNRFYDWEYQTDEEPHMGRRVDHARGKVLGGSSSINGMIYQRGNPMDYEGWAEPEGMDTWDFAHCLPYFKKLETTYGAAPYDKVRGHDGPIKLKRGPATNPLFKSFFNAGVEAGYHKTADVNGYRQEGFGPFDSQVHHGRRMSASRAYLRPALRRRNLDVETRAFVTKLIFDENNSKKVTGVTFKKNGKEHTVHANEVILSGGAFNTPQLLQLSGIGDSEFLKSKGIEPRMHLPGVGENFEDHLEVYIQHKCKQPVSLQPSLDVKRMPFIGLQWIFARKGAAASNHFEGGGFVRSNDDVDYPNLMFHFLPIAVRYDGQKAPVAHGYQVHVGPMYSNSRGSLKIKSKDPFEKPSIVFNYLSTKEDEREWVEAIRVARNILKQKAMDPFNGGEISPGPQVQTDEEILDWVRKDGETALHPSCSAKMGPASDPMAVVDPLTMKVHGMENLRVVDASAMPRTTNGNIHAPVLMLAEKAADIIRGRKPLEPQYVDYYKHGIDDEKAGAMEDDPFYQY
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
What are the official names of this protein?
Oxygen-dependent choline dehydrogenase, CDH, CHD, Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: DATPH_BPS2L
Sequence: MTLQITETYERLRASHISRWGIVQTTYPQNIAEHMWRVWLLCRDWGAAAGMPQHTVRQACEFALVHDLAEIRTGDAPTPHKTPELKELLAGIEAQIVPEVAELEATMAPEARELWKFCDTAEAVLFLKVNGLGAHAYDVQHLLMEQMKRRLMDSVLDVEVQDELMFQFERTIKKT
What is the function of this protein?
Catalyzes the hydrolysis of dATP, dADP and dAMP into dA (PubMed:33926954, PubMed:33893297).  This step is essential for Z-genome synthesis (containing aminoadenine instead of adenine).  Specifically removes dATP and its precursor dADP from the nucleotide pool of the host, preventing the incorporation of A into the phage genome and favoring the integration of the Z-base into the viral genome (PubMed:33926954, PubMed:33893297).
What are the official names of this protein?
dATP triphosphohydrolase, dATPase, DatZ.
What is the protein family that this protein belongs to?
Belongs to the Caudovirales dATP triphosphohydrolase family.