PharMolix/UniProtQA huggingface dataset:
Protein: RL15_ANASK
Sequence: MSLNQLKAPRGANRAKKRVGRGQGSGLGKTAGRGGKGQKARSGNMHFEGFEGGQMPLQRRLPKFGFHNIFRRELEEVKVGDLQGLSGVVDPAALKSAGLVRGNRDGVVVLAGGELSSALTVKVHRVTAGARATIEKAGGKVELIPAPQTMHQKAKAAKKAAAQAK
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: RL29_BURO1
Sequence: MKASELLQKDQAALNKELADLLKAQFGLRMQLATQQLTNTSQLKKVRRDIARVRTVMTQKANQK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: PDPK1_CAEEL
Sequence: MEDLTPTNTSLDTTTTNNDTTSDREAAPTTLNLTPTASESENSLSPVTAEDLIAKSIKEGCPKRTSNDFMFLQSMGEGAYSQVFRCREVATDAMFAVKVLQKSYLNRHQKMDAIIREKNILTYLSQECGGHPFVTQLYTHFHDQARIYFVIGLVENGDLGESLCHFGSFDMLTSKFFASEILTGLQFLHDNKIVHRDMKPDNVLIQKDGHILITDFGSAQAFGGLQLSQEGFTDANQASSRSSDSGSPPPTRFYSDEEVPEENTARRTTFVGTALYVSPEMLADGDVGPQTDIWGLGCILFQCLAGQPPFRAVNQYHLLKRIQELDFSFPEGFPEEASEIIAKILVRDPSTRITSQELMAHKFFENVDWVNIANIKPPVLHAYIPATFGEPEYYSNIGPVEPGLDDRALFRLMNLGNDASASQPSTFRPSNVEHRGDPFVSEIAPRANSEAEKNRAARAQKLEEQRVKNPFHIFTNNSLILKQGYLEKKRGLFARRRMFLLTEGPHLLYIDVPNLVLKGEVPWTPCMQVELKNSGTFFIHTPNRVYYLFDLEKKADEWCKAINDVRKRYSVTIEKTFNSAMRDGTFGSIYGKKKSRKEMMREQKALRRKQEKEEKKALKAEQVSKKLSMQMDKKSP
What is the function of this protein?
Involved in the daf-2/insulin receptor-like transduction pathway, which controls longevity and prevents developmental arrest at the dauer stage (PubMed:10364160, PubMed:21980302).  Phosphorylates and activates sgk-1, akt-1 and akt-2 (PubMed:15068796).
What are the official names of this protein?
3-phosphoinositide-dependent protein kinase 1, Pdk-class protein kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BEPA_ECO57
Sequence: MFRQLKKNLVATLIAAMTIGQVAPAFADSADTLPDMGTSAGSTLSIGQEMQMGDYYVRQLRGSAPLINDPLLTQYINSLGMRLVSHANSVKTPFHFFLINNDEINAFAFFGGNVVLHSALFRYSDNESQLASVMAHEISHVTQRHLARAMEDQQRNAPLTWVGALGSILLAMASPQAGMAALTGTLAGTRQGMISFTQQNEQEADRIGIQVLQRSGFDPQAMPTFLEKLLDQARYSSRPPEILLTHPLPESRLADARNRANQMRPMVVQSSEDFYLAKARTLGMYNSGRNQLTSDLLDEWAKGNVRQQRAAQYGRALQAMEANKYDEARKTLQPLLAAEPGNAWYLDLATDIDLGQNKANEAINRLKNARDLRTNPVLQLNLANAYLQGGQPQEAANILNRYTFNNKDDSNGWDLLAQAEAALNNRDQELAARAEGYALAGRLDQAISLLSSASSQVKLGSLQQARYDARIDQLRQLQERFKPYTKM
What is the function of this protein?
Functions as both a chaperone and a metalloprotease.  Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
What are the official names of this protein?
Beta-barrel assembly-enhancing protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48 family. BepA subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: RS3_ECO55
Sequence: MGQKVHPNGIRLGIVKPWNSTWFANTKEFADNLDSDFKVRQYLTKELAKASVSRIVIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAGVPAQINIAEVRKPELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRLGAKGIKVEVSGRLGGAEIARTEWYREGRVPLHTLRADIDYNTSEAHTTYGVIGVKVWIFKGEILGGMAAVEQPEKPAAQPKKQQRKGRK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: P3H3_MOUSE
Sequence: MLRLLRLLLLLLLPPPGSPEPPEPPGLAQLSPGSPPQAPDLLYADGLRAYSAGAWAPAVALLREALRSRAALGRARQECGASCAAEPGAALPSQLLGAPHPVSGPGVWEPLLLRATLRRAECLTQCAVRRLGPGGAARLRVGSALRDAFRRREPYNYLQRAYYQLKKLDLAASAAHTFFVANPTHLQMREDMAKYRRMSAIRPQSFRDLVTPLYWAAYDTGLELLEQREAALALPQLEEALQGSLAHMESCRAACEGPEEHQGAEEEGEGSQGGLYEAIAGHWIRVLQCRQHCVADTATRPGRSFPVQDFLLSQLRRLHEAYAQVGNMSQAMENVLSVLLFYPEDEAAKKALNQYQTQLGEPRPDLGPREDIQRFILRSLGEKRQLYYAMEHLGTSFKDPDSWTPEALIPKALRERLREDQEKKPWDHQPPQQKPLAHWKDALLMEGVTLTQDAQQLNGSERAVLDGLLTSAECGVLLQLAKDAAQAGARSGYRGRRSPHSPHERFEGLTVLKAAQLARAGTVGRPGAKLLLEVSERVRTLTQAYFSPERPLHLSFTHLVCRSAIEGEQEQRMDLSHPVHADNCVLDPDTGECWREPPAYTYRDYSGLLYLNDDFKGGDLFFTQPNALTVTAQVRPRCGRLVAFSSGGENPHGVWAVTRGRRCALALWHTWAPEHSEQEWTEAKELLQEEEEEEEEEDILSRDPSPEPPSHKLQRVQEKAGKPRRVRVREEL
What is the function of this protein?
Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linkling of collagen fibrils (PubMed:27119146).  Required for normal hydroxylation of lysine residues in type I collagen chains in skin, bone, tendon, aorta and cornea (PubMed:28115524).  Required for normal skin stability via its role in hydroxylation of lysine residues in collagen alpha chains and in collagen fibril assembly (PubMed:27119146, PubMed:28115524).  Apparently not required for normal prolyl 3-hydroxylation on collagen chains, possibly because it functions redundantly with other prolyl 3-hydroxylases (PubMed:28115524).
What are the official names of this protein?
Prolyl 3-hydroxylase 3, Leprecan-like protein 2, Protein B.
What is the protein family that this protein belongs to?
Belongs to the leprecan family.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: P40_SCHMA
Sequence: MSGGKQHNAVSIPVNREQRSFEKQRRDLLTGLEHGGGAHRGNSIAPYTEDWPSTVDNWIDSSWKRWDDDMRRLRRGMFALLPLDTFSIGILENPFALMHQMDRQIQDIRERMGSLDVPSTGSVNDFLKDAYEVGEDGKVHFKVRFDAQGFAPQDINVTSSENRVTVHAKKETTTDGRKCSREFCRMVQLPKSIDDSQLKCRMTDDGVLMLEAPVKVDQNQSLTLNESGQVAVRPKSDNQIKAVPASQALVAKGVHGLSYVDDGSGGKRLHVEVAVDPVYKPEDLFVNVDSNRVVVSGRHHKQKSDQHGRSSSFAEFSQSYAIPETVDPLSVSAQVVGNTLVLEAPLEKQHAITH
What are the official names of this protein?
Major egg antigen, p40.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
Protein: YBEY_STAA8
Sequence: MFTIDFSDHTGLVKDAWYKQIEDLLEFAKKEEHIEDDAELSVTFVDKQEIQEINRTYRDKDKVTDVISFALEEDEPEIDFSGLDIPRVLGDIIICTDVAQEQANNYGHSFERELGFLALHGFLHLLGYDHMTEADEKEMFGRQDTILNAYGLTRD
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FDHD_XANC5
Sequence: MTSPSSRSVRPGSVVRTVRRHRGGRSATVQDMVAAEMPVAFIYNGVPFAVMMATPEDLEDFALGFSLSEGIVDHAQDLRVIAVETFLEGASLQIEIPPERAAALDQRRRNLDGRSGCGVCGNESIEAVLRVPPVLHSSLQIDVDALAHALDALHARQPIAAQTGAVHAAAWADAQGNVQLVREDVGRHNALDKLIGALARARIDASHGFAVVTSRASYEMAMKAAQARIPLLAAISAPTALAISLAESAGLTLIGFARDHDCVVYSHPQRLDLGVAVGEPA
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity.  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
What are the official names of this protein?
Sulfur carrier protein FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX2_HALGR
Sequence: MAYPLQMGLQDATSPIMEELLHFHDHTLMIVFLISSLVLYIISLMLTTKLTHTSTMDAQEVETVWTILPAIILILIALPSLRILYMMDEINNPSLTVKTMGHQWYWSYEYTDYEDLNFDSYMIPTQELKPGELRLLEVDNRVVLPMEMTIRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQTTLMAMRPGLYYGQCSEICGSNHSFMPIVLELVPLSHFEKWSTSML
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RGS5_PIG
Sequence: MCKGLAALPHSCLERAKEIKIKLGILLQKPESAVDLVIPYNEKPDKPVKIQKPSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWMACEDYKKIKSPVKMAEKAKKIYEEFIQSEAPKEVNIDHFTKEITMKNLVEPSPSSFDVAQKRIYALMEKDSLPRFVRSEFYQEFIK
What is the function of this protein?
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.  Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha (By similarity).
What are the official names of this protein?
Regulator of G-protein signaling 5, RGS5.
What are the subcellular locations of this protein?
Cytoplasm. Membrane.
Protein: NUR1_YEAS1
Sequence: MGSNDLINEAYDDSEVVGEERESKSAWMKRWYQLLTSPLDLQLVINEKLEMINWDAYAKSLAKPLGNFLTILFFIIRLLQDNLIKPNYYKLNVKSGAFDLSKSNKLKEFDYLWEISSSFQNSNQFYAFQSWYFVTLRFLNNLFRFTIFILLSLNLYVSCKFMFGYFKTYNLFHLKKEFNSPNLTKHNLKDLSKEYYEDIYKQSLWSMLKHFFRGSRDDGPHVNQNEDEIFFQLRKWIPTNFMINLFVSFSPTAIVFLSFSDVSFTSAIAIVFHQYILDYIITKRFQRSVDDDLILSSAALQEYEDKHIMARINQCSNIDTLSSAMGTRSKTPRIFTTHSLCGEEIREVYNYEKREFEALPKMTESVPGSRETRIKDYGGISQVSDNQSHPIGFHYSPRMSPYYRDKVLDNNLAQSSSNENLEKGGAFLPNQDQNRPSKSLSPLRKTPLSARQKRFEGSEFNVLNKNDINSILRSPKKKKNYHKR
What is the function of this protein?
Member of a perinuclear network that controls recombination at multiple loci to maintain genome stability.  Required for rDNA repeat stability (By similarity).
What are the official names of this protein?
Nuclear rim protein 1.
What is the protein family that this protein belongs to?
Belongs to the NUR1 family.
What are the subcellular locations of this protein?
Nucleus membrane; Multi-pass membrane protein.
Protein: LEUC_LACLS
Sequence: MTAKTIFDKLWDRHVVAGNEGEPQLLYIDLHVIHEVTSPQAFQGLRDAGRSVRRRDLTYGTLDHNVPTKDIFNIQDLISKKQIDTFTKNVKEFGIPAEAHGGKGQGIVHMVAPESGRTQPGKTIVCGDSHTATNGAFGAIAFGIGTSEVEHVLATQTIWQVKPKRMKIEFQGHPQKGVYSKDFILALIAKYGVDAGVGYAVEYTGNAISDLSMEERMTICNMSIEFGAKMGQMNPDEKTYDYVKGREYAPENFDEAVSKWEKLVSDSDAVYDKVLTLDVSQLKPMVTWGTNPGMGLEFGEEFPKINDDLNYERAYQYMDLKPGQTASDIDLGYIFIGSCTNARLGDLEEAAKIIKGNHIADGLTGIVVPGSRPVKIADEELGLDKIFKNAGFEWREPVCSACLGMNPDQIPAYVHCASTSNRNFEGRQGHNARTHLCSPAMAAAAAIAGKFVDVREIV
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: ACDH_RALSO
Sequence: MTRKLKVAIIGSGNIGTDLMIKVLRHGGPIEMGAMVGIDPGSDGLARAARLGVPTTAEGLEGLLRLPGFKDIGLVFDATSAGAHHRHAARLAELGVPMIDLTPAAIGPYVVPVVNGEAHRGARNINMVTCGGQATIPIVAAVSQVARVHYAEIVASIASRSAGPGTRANIDEFTETTSRAIEAVGGAERGKAIIILNPAEPPLMMRDTVFTFSAPASESEVEASIEAMVAKVQAYVSGYRLKQRVQFEHTEVALPGAGRVRGLKTTVLLEVRGAAHYLPEYAGNLDIMTSAALACAQAQAAALIAA
What are the official names of this protein?
Acetaldehyde dehydrogenase, Acetaldehyde dehydrogenase [acetylating].
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: RFA2_PONAB
Sequence: MWNSGFESYGSSSYGGAGGYTQSPGGFGSPAPSQAEKKSRARAQHIVPCTISQLLSATLVDEVFRIGNVEISQVTIVGIIRHAEKAPTNIVYKIDDMTAAPMDVRQWVDTDDASSENTVVPPETYVKVAGHLRSFQNKKSLVAFKIMPLEDMNEFTTHILEVINAHMVLSKANSQPSAGRAPISNPGMSEAGNFGGNSFMPANGLTVAQNQVLNLIKACPRPEGLNFQDLKNQLKHMSVSSVKQAMDFLSNEGHIYSTVDDDHFKSTDAE
What is the function of this protein?
As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress.  It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism.  Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.  In the cellular response to DNA damage, the RPA complex controls DNA repair and DNA damage checkpoint activation.  Through recruitment of ATRIP activates the ATR kinase a master regulator of the DNA damage response.  It is required for the recruitment of the DNA double-strand break repair factors RAD51 and RAD52 to chromatin in response to DNA damage.  Also recruits to sites of DNA damage proteins like XPA and XPG that are involved in nucleotide excision repair and is required for this mechanism of DNA repair.  Also plays a role in base excision repair (BER) probably through interaction with UNG.  Also recruits SMARCAL1/HARP, which is involved in replication fork restart, to sites of DNA damage.  May also play a role in telomere maintenance.
What are the official names of this protein?
Replication protein A 32 kDa subunit, RP-A p32, Replication factor A protein 2, RF-A protein 2.
What is the protein family that this protein belongs to?
Belongs to the replication factor A protein 2 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, PML body. Note=Redistributes to discrete nuclear foci upon DNA damage in an ATR-dependent manner.
Protein: SUI1_METBF
Sequence: MSSGMCPVCGLPKELCICEEVAKEQQRITVKVNRRRYGKEVTVVEGFDASEIDLHELSTYLKSKFACGGTVKGNTVELQGNHLARMKEVLMEKGFSAEQIKN
What are the official names of this protein?
Protein translation factor SUI1 homolog.
What is the protein family that this protein belongs to?
Belongs to the SUI1 family.
Protein: SLX9_YEAST
Sequence: MVAKKRNTLRSKVSARNSQNFGPDVANNGILDESYDIESDPRAFLHQPKETKKEKLLNRQNTFLSNLKGKSTLNDGIAANFDGISKSSIRRRKRKLREELKPRMQDLLTSLEQEKDLRGIIENSSKDMNNDDDIDMDSKIRFVDTKEMNLKKIEPGSVRIKKNQPNIRNQKGAKALAANETARFNQVLTNQDFQKNPFGALREVIKLQKQ
What is the function of this protein?
Involved in ribosome biogenesis.  Required for normal pre-rRNA processing in internal transcribed spacer 1 (ITS1).  May be involved in the movements of the replication forks.
What are the official names of this protein?
Ribosome biogenesis protein SLX9.
What is the protein family that this protein belongs to?
Belongs to the SLX9 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: KITA_DANRE
Sequence: MEYHCVLFTVLLQLIIQPGRSRPTITPEGPRLTVPLYSNFSLHCQSNSTVRWQHENRPMRTLKEEQRQGQQTILKVNRAGPQHLGKYSCREEKTGEKSSIYVYVKDPENPFRRTIVFDIVAAEGDTTVIPCLATDPDMKNLNLQKCDGQPLPNSLRYSASLETGVSVEKVRKEFEGCYVCVGTLDAATVKSGRYQLTVRLVPDAPPPITLGQPQRVLLTQGEKLSLSCSTSNVNSDIAVKWKAPNGVNPSVHQNSHLLTEPITHVRTAILSLSSVTMQDAGNYSCEAINEKGTTAKPVWVNIYEKGFINITSVDNSTRRVRAGESLSLRVVMNAYPKPHTFSWSYSGVKLTNTTDHVITSRTHGNSYTSELKLVRLKVSESGIYTFSCLNRDATIRQTFEVHVISKPQIVSYEGPIDGQVRCVAEGYPTPQIKWYYCDLPHSRCSNLLNATQEEEDVVTVTMTNPPFGKGAVESRLNITKNNYATLECVASANGEIVYTLFSISENTVPHELFTPLLIGFVAAAVILVLILIVLTYKYMQKPKYQIQWKVIEGIHGNNYVYIDPTQLPYDHQWEFPRDKLRFGKTLGSGAFGKVVEATAYGMSKADTVMTVAVKMLKPSAHATEKEALMSELKVLSYLGNHINIVNLLGACTVGGPTLVITEYCCFGDLLNFLRRRRVYFYYTTLGEDAYYRNVMMQSEPNDSRNGYMTMKPSVLGILSSENRRSLNKGDSYSDSDAVSEILQEDGLTLDTEDLLSFSYQVAKGMDFLASKNCIHRDLAARNILLTQGRVAKICDFGLARDITTDSNYVVKGNARLPVKWMSPESIFECVYTFESDVWSYGILLWEIFSLGSSPYPGMPVDSKFYKMIKEGYRMESPEFSPSEMYDIMHSCWDADPVKRPSFSKIVEKIEQQISDSTKHIYLNFSSRLPAAPGPREESSSHVHRLNSVGSHSTATQPLLSSNDVFLDRSSPSHPVV
What is the function of this protein?
Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine kitlg/scf and plays a role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, and in mast cell development, migration and function.  Required for the migration of cells in the melanocyte lineage and the survival of embryonic melanocytes.  Required for the differentiation of some, but not all, melanocytes.  Not essential for hematopoiesis or primordial germ cell development.
What are the official names of this protein?
Mast/stem cell growth factor receptor kita, SCFR, Tyrosine-protein kinase Kit.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: YCF33_PORPU
Sequence: MSRFWNNVVKFPRFLVSVILGLILTIISPFFVLFRKPSTSFFFIISFTGLLVVLTAIIKKMLNIECC
What are the official names of this protein?
Uncharacterized protein ycf33.
What is the protein family that this protein belongs to?
Belongs to the ycf33 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FUMC_XYLFA
Sequence: MEMQMSNSDRYRIEHDSMGDLRVPIDALWGAQTQRAIENFPISGRSMPQGFIHALGFIKAAAAKVNAELGLLPKPMAKEIEAAALDVAAGRYDADFPVDIYQTGSGTSSNMNANEVIATLAMRATKEPIHPNDHVNLGQSSNDVVPTAIRISATLAVQGRLLPALKHLRKMINKRARGLGSVVKTGRTHLMDAMPLTFAQEFGAWSAQIVSAEARLNDTLKRLHRLPLGGTAIGTGINTDPHFGRNAVKVLSALTGIHFESANNKFEGLAAQDDLVELSGQFNALAVALMKIANDLRWMNAGPLAGLGEIELPALQPGSSIMPGKVNPVIPEAVVMVASQVIGHHTAVTVAGQSGNFQLNVTLPLIAYNLLESATLLGNVVMLLADKVIVGLKVRQDRVQEVLERNPILVTALNPIIGYEKAAVIAKRAYKEHRPVLEVACEESNLNPVELARLLDPTALTEGGIYVVGGGGG
What is the function of this protein?
Involved in the TCA cycle.  Catalyzes the stereospecific interconversion of fumarate to L-malate.
What are the official names of this protein?
Fumarate hydratase class II, Fumarase C, Aerobic fumarase, Iron-independent fumarase.
What is the protein family that this protein belongs to?
Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROE_LEGPC
Sequence: MLRRFAVIGNPIAHSLSPVIHQMFAQQTQIELIYEKILGDDVKFEQQISDFFIQYGNGLNVTLPYKKRAYELAKIRTQRCALAGVANTLWMEENQLHADNTDGIGLIRDLSRFLELKDKKILILGAGGAARGIIFPLLEAKPLKLIVANRTLEKAEELKRQFPQINVTSFAELPEFFDLIINATSASLSDQVIALPEEAFSHKPFCYDLAYNQKTSTAFVQYARNGGCEAVDGLGMLVEQAAEAFFIWNKVMPSTQKILEHLRSF
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: QCR9_DICDI
Sequence: MSNALTNIFYKYVARRNSTWMAGAILGAFVLDSTVSGAVNTFFDSVNKGKLWKDVYAERVKKGISQ
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol.  In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
What are the official names of this protein?
Probable cytochrome b-c1 complex subunit 9, Ubiquinol-cytochrome c reductase complex subunit 9.
What is the protein family that this protein belongs to?
Belongs to the UQCR10/QCR9 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: NADE_PSYIN
Sequence: MKQQILQEMRVLVTINEEIEIKRRINFIKKKLQQAECYTLVLGISGGVDSSTAGRLCQLAVEQLNQSTDTDKYQFIAVRLPYAIQKDEDEAQLALQFIRPSHVITINIKNGADGIHESTLAALQTSSVNLSADTNIDFIKGNVKARMRMIAQYEIAGLTGGLVVGTDHSAENITGFYTKHGDGACDLAPLFGLNKRQIRALAKQLGAPAILIEKAPTADLEEDKPQLQDEHALGITYDQIDDFLEGKAVTQEIEDKLIAIYLRTQHKRQAVPTIYD
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: UNG_HCMVM
Sequence: MALKQWMLANIADNKGSLLTPDEQARVFCLSADWIRFLSLPDHDTVLLRDTVAAVEGARQLEMVYPAPEHVHRWSYLCPPEQVRVVIVGQDPYCDGSASGLAFGTLAGRPPPPSLNNVFRELARTVDGFQRPASGCLDAWARRGVLLLNTVFTVVHGQPGSHRHLGWQTLSNHVIRRLSERREHLVFMLWGADAHTCEYLIDRRRHLVLKSCHPSPRNTTRAFVGNDHFILANAYLDTHYRETMDWRLCG
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or deamination of cytosines.  Therefore may reduce deleterious uracil incorporation into the viral genome, particularly in terminally differentiated cells which lack DNA repair enzymes.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG, UNG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: FLGE_CAUVC
Sequence: MSINSAMLAGVSGLIANSSALAAISDNIANVNTVGFKRSTSNFSTLVTSGNKNQTYSAGGVKAQTHQFISQQGLTQSTTSNLDISISGAGFFVTTEKPENLTATDTRSFTRAGSFQLDNLGYLRNDAGLYLQGWLADPVSGLITPDPSDLMQLASINVGSVGGTAEKTTRVGVNANLRSEQPVAAAVSYKVGTAGSPSKTNVVDSATNSHNYDVVYSSTGIANPVSGNNEYLVDIKENGVIVATGKVAYDAATNELVSSTIDYKGASPVTGSMTTTRINAAGTTVNLADLGIVNASGADDAEVVAGKLYDPSTWSMSDYAKDNSKGVKPDFEVQIPLSDSKGGQRTVTLSMLKGPGPNQWYAELRAKPGDLANNGNGQISTGIIEFTTDGKLKNTGSLFGTTSPTAITIKSSGYIAPTVTPPAVQPPTPPTWADALGIDEQEVQIDLASAAGGLTQYNSQSVVQSVNTNGTAFGNLTNIEIDEGGYVSAIFDNGVTRRIAQVAIATFSNPNGLKGVNGNAYRVTNESGTYSLKAPSQGGAGALAPSTLEASTVDLSQEFTGLITTQRAYSASSKIITTADQMLEELLNIKR
What are the official names of this protein?
Flagellar hook protein FlgE.
What is the protein family that this protein belongs to?
Belongs to the flagella basal body rod proteins family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: AOC3_ARATH
Sequence: MASSSAAMSLESISMTTLNNLSRNHQSHRSSLLGFSRSFQNLGISSNGPDFSSRSRSTTSKNLNVTRAFFWNWGKKTENSRPSKIQELNVYELNEGDRNSPAVLKLGKKPTELCLGDLVPFTNKLYTGDLKKRVGITAGLCVLIQHVPEKSGDRFEASYSFYFGDYGHLSVQGQYLTYEDTFLAVTGGSGIFEGAYGQVKLRQLVYPTKLFYTFYLKGLANDLPLELTGTAVTPSKDVKPAPEAKAMEPSGVISNFTN
What is the function of this protein?
Involved in the production of 12-oxo-phytodienoic acid (OPDA), a precursor of jasmonic acid.
What are the official names of this protein?
Allene oxide cyclase 3, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the allene oxide cyclase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PYRB_PELPD
Sequence: MANFKHKDIIALQDLTKQEIELLLSTAESMREINNRDIKKVPTLRGKTIVNLFYESSTRTRTSFELAAKRLSADTVNISPSTSSATKGETLADTALNLLAMKPDIIVMRHSVSGSHYFLSKKLPCSIVNAGDGVHEHPSQGLLDMLTMKDRFGRLDGLKVAIVGDISHSRVARSNIQGLTKLGSQVFLAGPPTMMPPGVERLGNVTVCDSLREAIQDADVVMMLRIQQERQGKTLMPNAREYARYFGLNPENLKLAKPDAMVMHPGPINRGVEMASSVVDGDQSWILKQVENGVAVRMSMLYHVCEGELE
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.