PharMolix/UniProtQA huggingface dataset:
Protein: APT_PECCP
Sequence: MMTVTAQQQAELIKNSIKSIPDYPKPGILFRDVTSLLEDPVAYAASIEMLANRYRNSGVTKVVGTEARGFLFGAPVALALGVGFVPVRKPGKLPRPTISESYELEYGSDTLEIHSDAISAGDNVLVIDDLLATGGTLEATVKLIRRLGGTVNDAAFIINLFDLGGEQRLTGMGVTCYSLVDFPGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAD2A_XENLA
Sequence: MCRKEPFLLPTALCILAALVLHQGPVEALGGSRLCKTGFLEDVYHASVYRSVHEGQPLLNVKFTDCGADRRIHYETSNPTDFRIDGDGIVCASRTFDISPEQAEFLVYAQDEDTRELWHVTVKITLRPRHVQDLHQGFHKVREIKFSTQRKHNGLQRQKRDWVIPPINVPENARGTFPQELVGIRSDRDKSLSLRYSVTGPGADQPPLGVFIINPISGQLSVTKPLDREQIATFHLRAHAVDVNGNQVENPIDIVINVIDMNDNRPEFLHQIWNGTIPEGSKPGTYVMTVTAIDGDDPKQPNGMLRYKILSQTPASSSPNMFTINNETGDIITLAAGLDREKVQRYTLIIQATDMEGNPTYGLSNTATAVIAVTDVNDNPPEFTAMTFYGEVPENRVDVVVANLTVTDKDQPHTPAWNAVYRIVGGDGTGRFAIKTDANSNDGLVTVVKPIDYETKSTYILTVVAENQVELIRGIQYKPESTATVSVTIIDVNENPYFTPNPKLIRQEEGLFAGKLLTTFSAQDPDRYMQQTIRYSKLSDPANWLKIDPVNGFITTTAVLDRESIYVKNNMYNATFLATDSGIPPMSGTGTLQIYLLDINDNAPYVYPQEVEICDRPDPNAINITALDADINPNAGPFIFELPYSPMDIKKNWTVTRLSGDHAQLSLKIGSLDYGIYNIPIQITDSGNPAMSNTSYLRVKVCSCEHGYCSTTAPIIGTGLGTGAIIAILLCIIILLTLVLMFVVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGEEDQDYDLSQLQQPDTVEPDTIKPVGIRRMDERPIHAEPQYPIRSAAPHPGDIGDFINEGLKAADNDPTAPPYDSLLVFDYEGSGSTAGSLSSLNSSSSGGEQDYDYLNDWGPRFKKLADMYGGSDD
What is the function of this protein?
Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion.  Cadherins may thus contribute to the sorting of heterogeneous cell types, and thereby play an important role during embryonic development.  Required for proper neurite branching.  Required for pre- and postsynaptic organization (By similarity).
What are the official names of this protein?
Cadherin-2A, Neural cadherin A, N-cadherin A, Neural cadherin-2, N-cadherin-2.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell membrane, sarcolemma. Cell junction. Cell surface.
Protein: CT54_CONIM
Sequence: MRCLPVVVFLLLLLSAAAAPGVGSKTERLPGLTSSGDSDESLPFLNTICCWSGACCGG
What is the function of this protein?
Probable neurotoxin.
What are the official names of this protein?
Conotoxin Im5.4, Conopeptide im023.
What is the protein family that this protein belongs to?
Belongs to the conotoxin T superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: AX22E_VIGRR
Sequence: MGSYETELNLRATELRLGLPGSDEPQEKRPCSGSVVRSSNKRSSPELEESRCKSNINSDSSDSTTTSDHNEDSVQPAKVQVVGWPPIRSFRKNSLQQKKVEQGDGTGMYLKVSMAGAPYLRKIDLKVYKSYPELLKALQNLFKCTFGEYSEREGYNGSEYAPTYEDKDGDWMLVGDVPWNMFVSSCKRLRIIKGSEAKGLGCL
What is the function of this protein?
Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations.  Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin-responsive promoter element (AuxRE).  Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression (By similarity).
What are the official names of this protein?
Auxin-induced protein 22E, Indole-3-acetic acid-induced protein ARG14.
What is the protein family that this protein belongs to?
Belongs to the Aux/IAA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ERA_SALCH
Sequence: MSTDKTYCGFIAIVGRPNVGKSTLLNKLLGQKISITSRKAQTTRHRIVGIHTEGPYQAIYVDTPGLHMEEKRAINRLMNKAASSSIGDVELVIFVVEGTRWTPDDEMVLNKLRDGKAPVILAVNKVDNVQEKADLLPHLQFLASQMNFLDIVPISAETGMNVDTIAGIVRKHLPEAIHHFPEDYITDRSQRFMASEIIREKLMRFLGAELPYSVTVEIERFVTNERGGYDINGLILVEREGQKKMVIGNKGAKIKTIGIEARKDMQEMFEAPVHLELWVKVKSGWADDERALRSLGYVDDL
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: RIMP_HELHP
Sequence: MLSQHTQARIEQLAATLGLYIYDIDFFKEDNRPILRVSITRKAPMQKQDCKNGLAVSLQDCQNVSELISPLLDVEDENLKDYNLEVSSPGLERVLKKPQHYIYSLGEKVSIKLMDKSVIEGILHDVNENVSISIDTGKEILSFSFADMKKIKVVFEL
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPD_RICRS
Sequence: MFVDKTLMITGGTGSFGNAVLSRFLKSGIINDIKEIRIFSRDEKKQEDMRIALNNPKLKFYIGDVRNYKSIDEAMHGVNYVFHAAALKQVPTCEFYPMEAINTNVLGTENVLSAAINNKVTKVIVLSTDKAVYPINAMGLSKALMEKLAIAKARMRSSGETVLCVTRYGNVMASRGSVIPLFINQIKQGKELTITEPSMTRFLMSLVDSVDLVLYAFEHGNQGDIFVQKSPASTIEVLAKALQDIFNSKNEIRFIGTRHGEKHYESLVSSEEMAKADDLRDYYRIPMDGRDLNYAKYFVEGEKKVALLEDYTSHNTKRLNLEEVKELLLTLDYVQEELKNA
What is the function of this protein?
Epimerizes UDP-galactose to UDP-glucose.
What are the official names of this protein?
UDP-glucose 4-epimerase, Galactowaldenase, UDP-galactose 4-epimerase.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide synthase family.
Protein: SLX1_PYRTR
Sequence: MTDGLKIDSRPLPAFYCCYLLRSKNRKAFYIGSTPNPARRLGQHNGSSKGGAKRTSMQGKRPWEMTCIVTGFPSRFAALQFEWAWQNTHATRHIERDVREARKDELEKGRKNASPVKRSRPPMSLEARLKNLHHLLGVGSFSRWPLHVRFFAPDVFSQWEKHISKMNTSLRKSITIRLTPAELPKLAPDVSSEMRTHFIPEVIRAIPVAYEDIKPYVEKSMSTLRDGKTRDCGVCKKDVNVDRSLVLICPNETCCSVSHMSCLSQRFLAEEANKEAFIPIEGTCPSCHSPIKWSDMIKELSLRMRGEDELKTLFKTKRKKKQVDTTEDDTDEYPDIDDLNADLDEDLDETWMENVNEEDDKPRS
What is the function of this protein?
Catalytic subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination.  Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
What are the official names of this protein?
Structure-specific endonuclease subunit slx1.
What is the protein family that this protein belongs to?
Belongs to the SLX1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NSP4_ROTHC
Sequence: MDFINQTLFSKYTESNVDTIPYLLGLILALTNGSRILRFINSFIIICKHIVTTSKSAIDKMRKINNSEHNTKNAHEEYEEVMKQIREMRIHMTALFNSLHDDNVKWRMSESIRREKKHEMKMSDNRNEFKHSHNDTNICEKSGLETEVCL
What is the function of this protein?
The secreted form acts as an enterotoxin that causes phospholipase C-dependent elevation of the intracellular calcium concentration in host intestinal mucosa cells.  Increased concentration of intracellular calcium disrupts the cytoskeleton and the tight junctions, raising the paracellular permeability.  Potentiates chloride ion secretion through a calcium ion-dependent signaling pathway, inducing age-dependent diarrhea.  To perform this enterotoxigenic role in vivo, NSP4 is released from infected enterocytes in a soluble form capable of diffusing within the intestinal lumen and interacting with host plasma membrane receptors on neighboring epithelial cells such as integrins ITGA1/ITGB1 and ITGA2/ITGB1.
What are the official names of this protein?
Non-structural glycoprotein 4, NSP4, NCVP5, NS28.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP4 family.
What are the subcellular locations of this protein?
Host rough endoplasmic reticulum membrane; Single-pass type III membrane protein. Host membrane, host caveola; Single-pass type III membrane protein. Secreted. Note=NSP4 localizes also in vesicular structures which contain autophagosomal markers and associate with viroplasms in virus- infected cells. Additionally, a soluble form of glycosylated NSP4 is secreted despite retention of its transmembrane domain.
Protein: AF9_CANGA
Sequence: MAPPTSKRIKTLSVSRAVIYGNTAKKIGENRPPNAPSEHTHLWTIFVRSPTGDDISYFIKKVVFKLHETYPNPVRTIEAPPFELTETGWGEFDINIKIYFVEESNEKFINFYHRLRLHPYVNVNPPMSTEVKKEETGNATTSDEISSIFYDEIVFNEPYEDFFKILVSKPGNLLPSNKTEDCLFSRQLEQDELTRIKMASSNVDKEIEIYKKKLEDTLKSR
What is the function of this protein?
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling.  Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4 and H2A.  The NuA4 complex is also involved in DNA repair.  Yaf9 may also be required for viability in conditions in which the structural integrity of the spindle is compromised (By similarity).
What are the official names of this protein?
Protein AF-9 homolog.
What is the protein family that this protein belongs to?
Belongs to the YAF9 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GLCT_STAEP
Sequence: MSKYVITKTLNNNVIICTKNHQEVVLIGKGIGFNKKVGMTVQENASIEKIYKLEQQEQQEHYKTLLELGEDHVVQAVIESVNIINESGLITDDKNLVVALTDHIIYAYKRLKQHQMITNPFVIETKHLYSNAYNVARKVIDKLNKTLDVHFPEDEIGFIALHIASNSEKLSIHDISVINKLINKSITIIETDLQHSIDKQTIQYQRFIRHIQFLIYRLTKGEYLEAQENFISMIKTMYPRSFNTAYKILKMIQREFSVYVYEAEIVYLTLHINHFEVQISSE
What are the official names of this protein?
Protein GlcT.
What is the protein family that this protein belongs to?
Belongs to the transcriptional antiterminator BglG family. GlcT subfamily.
Protein: CL2DB_RAT
Sequence: MSAKKASQPMLNTTGSLQEGEMGKMFHGKCLRIVSPESPAKLYCCYGVIMVLSVAVVALSVALSVKMTPQISTINTYAACPRNWIGVGNKCFYFSEYASNWTFSQTFCKAQEAELARFDTEEELNFLSRYKGSFDYWIGLHRESSEHPWKWTDNTQYNYSLSIRGVERYAYLNDIGISSARVYADKRWSCSKLNSYSLQCKTPFSPM
What is the function of this protein?
Receptor for KLRB1B that protects target cells against natural killer cell-mediated lysis.
What are the official names of this protein?
C-type lectin domain family 2 member D11, C-type lectin-related protein B, Clr-b, Lectin-like transmembrane protein, Osteoclast inhibitory lectin.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: TRMD_FRATT
Sequence: MKMKFGIISIFPEMFKAINDFGVTARAIKDSKVSISCFNPRDYTTDRHATVDDTSFGGGAGMVMKYQPLSAAIEDAKNTLGCGTKVVYLSPQGSIFNHRKAQELLQNDSLILLCGRYEGVDERLIQDYVDEEISVGDFVLSGGELPAMLVMDSLIRLLPEVLGNKESVVEDSFYDGLLDYPHYTKPAVLPNGNAVPDVLLSGNHKEIAKWRRKQKLIRTYERRKDLIECLCLSAKDKQILDDYKIDKVSTKGEE
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTL_BORA1
Sequence: MYERRPIAQLPDLLISQIAAGEVIERPASVLKEILENAIDAGARAIEIRLEGGGIRRIAVSDDGFGIPPEELPLAVAQHATSKIRSLSELESVASMGFRGEALASIASVARLTIISRVRNGDHAWQIDASSGEISPASGPPGTTVDVRQLFDNVPARRKFLRSEATEFGHCLDALERIALANPQIAFRLFHHDKAQRQWLPADPGQRIRDVLGAEFAGQALPVDTRYGAIGLMGMVTRPTAARARADRQYLYVNGRYVRDRTVSHALRSAYADVLHGDRQPAYVLYLEVDPAAVDVNVHPAKHEVRFRDSGAVHRFVSQVVGQALAQTGGAQALDAEDPPPEPIRPETPPPPSLSPAAALPSAPAQPPAAPYPSRPHSQMPFRLQEPAGVSARDWQSLYRPLAEPGATPQTADRPQAAAPARLVSEEEHPLGMALGQLHGVYILAQNARGLVLVDMHAAHERVVYEQLKHALDERSLPRQDLLVPVVFHAQEKDVALAEEYAEQLSELGFEMRPSGPTSIAVRSVPALLARGDIEGLARAVLRDLGAVGASQLLTEQRNELLSTMACHGSVRANRRLTIEEMNALLRQMEATERADQCNHGRPTWIQWTVNDLDKLFLRGQ
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: AROC_SULAC
Sequence: MPGNSLGKMFRITTFGESHGPMIGVIVDGVPAGLYISKEDIEFELSFRRPGKQFVSGRREKDEPEIVSGVYNGRTTGAPLTIIIRNNDVISSLYEEVKHKPRPGHADLPYIMKYGYENWDYRGGGRSSARETASRVAASAIAKKLLMLTDTVIGAHLKSLGPVELDEDVSFREIFCSKYSPVRASKKWLEEKYEELIKQATVEGDSWGGVAEVIADNVPIGLGEPVFDKLKSDLAKALLSIPAVVGFEYGLGFKASKMKGSEANDEIVIKDNGKLGWRYNKAGGILGGLSNGEKLVLRCAFKPTSSIRKPQKTVDLRTSEESTIRVIGRHDPAVAIRGVSVAEAMVALVLVDHALRSGYIPPVKLSEDQARIIEEKWRRYVEECKPMQESQ
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: DHMA1_MYCTO
Sequence: MDVLRTPDSRFEHLVGYPFAPHYVDVTAGDTQPLRMHYVDEGPGDGPPIVLLHGEPTWSYLYRTMIPPLSAAGHRVLAPDLIGFGRSDKPTRIEDYTYLRHVEWVTSWFENLDLHDVTLFVQDWGSLIGLRIAAEHGDRIARLVVANGFLPAAQGRTPLPFYVWRAFARYSPVLPAGRLVNFGTVHRVPAGVRAGYDAPFPDKTYQAGARAFPRLVPTSPDDPAVPANRAAWEALGRWDKPFLAIFGYRDPILGQADGPLIKHIPGAAGQPHARIKASHFIQEDSGTELAERMLSWQQAT
What is the function of this protein?
Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons.
What are the official names of this protein?
Haloalkane dehalogenase 1.
What is the protein family that this protein belongs to?
Belongs to the haloalkane dehalogenase family. Type 1 subfamily.
Protein: NAR22_ORYSJ
Sequence: MARFGAVIHRVFLPLLLLLVVLGACHVTPAAAAAGARLSALAKALVVEASPRAGQVLHAGEDAITVTWSLNATAAAAAAGADAGYKAVKVTLCYAPASQVGRGWRKAHDDLSKDKACQFKIAQQPYDGAGKFEYTVARDVPTASYYVRAYALDASGARVAYGETAPSASFAVAGITGVTASIEVAAGVLSAFSVAALAVFLVLENKKKNK
What is the function of this protein?
Involved in nitrate transport.
What are the official names of this protein?
Probable high-affinity nitrate transporter-activating protein 2.2, OsNAR2.2.
What is the protein family that this protein belongs to?
Belongs to the NAR2 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: SYH_ECOSM
Sequence: MAKNIQAIRGMNDYLPGETAIWQRIEGTLKNVLGSYGYSEIRLPIVEQTPLFKRAIGEVTDVVEKEMYTFEDRNGDSLTLRPEGTAGCVRAGIEHGLLYNQEQRLWYIGPMFRHERPQKGRYRQFHQLGCEVFGLQGPDIDAELIMLTARWWRALGISEHVTLELNSIGSLEARANYRDALVAFLEQHKEKLDEDCKRRMYTNPLRVLDSKNPEVQALLNDAPALGDYLDEESREHFAGLCKLLESAGIAYTVNQRLVRGLDYYNRTVFEWVTNSLGSQGTVCAGGRYDGLVEQLGGRATPAVGFAMGLERLVLLVQAVNPEFKADPVVDIYLVASGADTQSAAMALAERLRDELPGVKLMTNHGGGNFKKQFARADKWGARVAVVLGESEVANGTAVVKDLRSGEQTAVAQDSVAAHLRTLLG
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLTRN_RAT
Sequence: MLWALFFLVTTIHAELCRPDAENAFKVRLSIKAALGDKAYVWDTDEEYLFRAMVAFSMRKVPNREGTEISHVLLCNVTQRVSFWFVVTDPLKNHTLPAAEVQSAIRMNRNRINSAFFLDDHTLEFLKIPSTLAPPMDPSVPVWIIVFGVIFCIVTVAIALLVLSGIRQRRRNKKGPPGVEDAEDKCENIITIENGIPCDPLDMKGGHINDGFLTEDERLTPL
What is the function of this protein?
Plays an important role in amino acid transport by acting as binding partner of amino acid transporters SLC6A18 and SLC6A19, regulating their trafficking on the cell surface and their activity (By similarity).  May also play a role in trafficking of amino acid transporters SLC3A1 and SLC7A9 to the renal cortical cell membrane (By similarity).  Regulator of SNARE complex function (PubMed:16330323).  Stimulator of beta cell replication (By similarity).
What are the official names of this protein?
Collectrin, Transmembrane protein 27.
What is the protein family that this protein belongs to?
Belongs to the CLTRN family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=Localizes to the brush border membranes of cells in the proximal tubules of kidney. Colocalized with SLC6A19 in the early proximal S1 tubule.
Protein: SYDND_ACIET
Sequence: MAMRSHYCGLVTEALLGQTVTLSGWVNRRRDHGGVIFIDLRDREGYVQVVCDPDRPEMFKVAEDVRNEFCVQVKGLVRARPEGTTNDSLKSGKIEVLCQELNVLNPSVTPPFQMDDDNLSETTRLTHRVMDLRRPYMQRNMMLRYKTAIQVRNFLDKEGFIDIETPMLGKSTPEGARDYLVPSRVHDGQFFALPQSPQLYKQMLMVAGYDRYYQITKCFRDEDLRADRQPEFTQIDCETSFLNEEEIRAIFQRMIKEVFQQQLGVDLGEFPTMTYQEAAHRFGSDKPDLRVKLEFTELTDVMKDVDFKVFSGAANMKGGRVVALRVPGGAREEGGLSRGEIDGYTEFVKIYGAKGLAYIKVNDKAKGRDGLQSPIVKNIHDAALAEVLQRTGAQDGDLLFFGADKEKIVNDAIGALRLKVGHSEFGKKNGLFENRWAPLWVVDFPMFEHDEEEDRWVAVHHPFTSPKDGHENLMDTDPGKCIAKAYDMVLNGWELGGGSVRIHRADVQAKVFAALNIGPEDQRAKFGYLLDALQYGAPPHGGLAFGLDRLITLMTGAESIRDVIAFPKTQRAQDLLTQAPSPVDEKQLRELHIRLRNPLPAAH
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMA_BACAN
Sequence: MKWSEISIHTTEEAVEAVSHILHEAGASGVAIEDPAELTKEREQQYGEIYALNPDEYPAEGVLIKAYFPQTDSLHETIAGVKSSIDVLPSYDIEIGTGNITVNEVNEEDWATAWKKYYHPVQISDTFTIVPTWEEYTPSSPEEKIIELDPGMAFGTGTHPTTTMCIRALEKTVQPGDTIIDVGTGSGVLSIAAAKLGASSVQAYDLDPVAVESAEMNVRLNKTDDVVSVGQNSLLEGIEGPVDLIVANLLAEIILLFPEDAARVVKSGGLFITSGIIAAKEKVISEALEKAGFTIEEVLRMEDWVAIIARNA
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLRA3_RAT
Sequence: MAHVRHFRTLLSGFYFWEAALLLSLVATKETNSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKTEAFALEKFYRFSDTDDEVRESRLSFTAYGMGPCLQAKDGVVPKGPNHAVQVMPKSADEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHHQQD
What is the function of this protein?
Glycine receptors are ligand-gated chloride channels.  Channel opening is triggered by extracellular glycine (PubMed:15131310, PubMed:23834509, PubMed:23895467, PubMed:23613537).  Channel characteristics depend on the subunit composition; heteropentameric channels display faster channel closure (PubMed:25445488).  Plays an important role in the down-regulation of neuronal excitability (By similarity).  Contributes to the generation of inhibitory postsynaptic currents (PubMed:25445488).  Contributes to increased pain perception in response to increased prostaglandin E2 levels (By similarity).  Plays a role in cellular responses to ethanol (PubMed:23895467).
What are the official names of this protein?
Glycine receptor subunit alpha-3.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA3 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Perikaryon. Cell projection, dendrite. Synapse. Cell membrane; Multi-pass membrane protein. Note=Partially colocalizes with GPHN that is known to mediate receptor clustering at postsynaptic membranes.
Protein: ATPA_MAGMM
Sequence: MQVSVAEISGILKKQIAEYGKEAEVSEVGEVIAVGDGIARAYGLDNVMAGEMVEFEDGTQGMALNLEEDNVGIVIFGEGLAIKEGTTVKRTGRIVDVPVGKGLLGRVTDGLGNPIDDKGPLETTERRLAEVKAPGIIPRKSVHEPLHTGIKALDGLVPIGRGQRELIIGDRQTGKTAVAIDTIINQKRTHETDSPVYCIYVAIGQKRSTVAQVVQTLEENGAMAYTTVVAATASDPAPMQFLSAYTGCAMGEYYRDNGMHALIVYDDLSKQATAYRQMSLILRRPPGREAYPGDVFYIHSRLLERAAKMNDEHGGGSLTALPIIETQDGDVSAYIPTNVISITDGQIFLETDLFYSGIRPAISVGLSVSRVGGSAQVKATKQVAGTLRLDLAQYREMAAFAQFGSDLDATTQKLLHRGKRLMELLKQAQYAPLSMEEQVVSIFAGTRGFLDVVDADAVVKAELELLKQMHAKHSDLLDTIRTSGKLDADTETKLGVAITAIIKEFLA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: UDB23_MACFA
Sequence: MSVKWTSVILLIQLSFYFSSGSCGKVLVWAAEYSHWMNMKTILEELVQRGHEVTALASSASILFDPNNSSALKIEVFPTSLPKPEFENIVTQEIKRWIELPKDTFWLYFSQMQEIMWKFGDIFRNFCKDVVSNKKLMKKLQESRFDVVFADPIFPCSELLAELFNIPLVYSLRFTPGYVFEKHCGGFLFPPSYVPVVMSELSDQMTFMERVKNMIYMLYFDFCFQIYDMKKWDQFYTEVLGRHTTLSEIMGKADIWLIRNSWNFQFPHPLLPNVDFIGGLLCKPAKPLPKEMEEFVQSSGENGVVVFTLGSMITNMKEERANVIASALAQIPQKVLWRFDGNKPDTLGVNTRLYKWIPQNDLLGHPKTKAFITHGGANGIYEAIYHGVPMVGIPLFADQPDNIAHMKTRGAAVQLDFDTMSSTDLVNALKTVINDPLYKENVMKLSRIQRDQPVKPLDRAVFWIEFVMRHKGAKHLRPAAHDLTWFQYHSFDVIGFLLACVATVIFIIMKCCLFCFWKFARKGKKGKSD
What is the function of this protein?
UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.  This isozyme has glucuronidating capacity on 6 steroids and the bile acid, hyodeoxycholic acid.  May potentially play an important role in estrogen and androgen catabolism in peripheral steroid target tissues.
What are the official names of this protein?
UDP-glucuronosyltransferase 2B23, UDPGT 2B23.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
What are the subcellular locations of this protein?
Microsome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: Y3920_CAUSK
Sequence: MTARKPFWETKSLNQMTVPEWESLCDGCGLCCLVRFEDEDTGEIIPTRVHCQLFDEHRCTCKDYANRKKTVPDCIKLTPHNIETLEWMPPSCAYRRLHEGKTLPLWHPLITGDRESVHQAGVSVRDQTVSELSFSDPEDALDFVATDLMYDKSDVDWDPEEP
What are the official names of this protein?
UPF0260 protein Caul_3920.
What is the protein family that this protein belongs to?
Belongs to the UPF0260 family.
Protein: RL21_SYNS9
Sequence: MADTKPAAKAAPETSDAYAIVEASGTQIWLQTNRYYDLDRLQADVDETLKLDNVLLVKDSKGTTLGQPYVKDASVELKVMAHRRGPKVIVYKMRPKKKTRRKNGHRQELTRVMVQSISVGGKAIG
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: RIMP_LEGPC
Sequence: MINDDLIVLLEPIIKNMGYELWGCEYLSQGKHSLLRIYIDKPDGIGIDDCQEVSKQVSAMLDVEDPIPGHYSLEISSPGIPRPLFSIWQYQRYLGYEIHVKTFKPVNGKRKLSGIIVSASEDTIVLDINNEHQEILLSNIVKANLTV
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.