PharMolix/UniProtQA huggingface dataset:
Protein: CLP1_DEBHA
Sequence: MSAIPGFGGDLNSNIDEDSNLNKSSVVEINGQSEWRFEVPFRTIMKLKVVNGIGEIFGTELPLNVEISLTGVKYAIYAPLDEGCKVEYYCVSNKANSTSTNEDDEISEYISEETSMNHYMNLHFALESYRQSISEHNFVNSSSQKTGPRVLVVGNRHSGKTSLVKTLASYGCKMDRSPILVNLNPRDGVFSVPGSLTATPISDAFDLESVNGWGGSTTSGSTFHNPKQPLVKNYGFTSHSDNLDLYKYQISKLGVAVVSRMEEDIAVKNSGLLIDTPPLSIKDFTIIENIVSDFEVNIIVVIGNERLLIDLKKKFKHKIASSQLDFVKVPKSGGVIEVDDAYIRKSQEESIKEYFNGTIRSPLSPFKTELDAKDFVIYKCVDSSEANSNLSFLPSGDSFTPEASEMSDGDKKEEFSLDTYYSQLQEPSSSNLDNSIVAITQLPQNNKSARDLMNTCVLGYAHVSKFDDTKSKMKVLLPFPGALPRNILISTSVGYTE
What is the function of this protein?
Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.
What are the official names of this protein?
mRNA cleavage and polyadenylation factor CLP1.
What is the protein family that this protein belongs to?
Belongs to the Clp1 family. Clp1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: HLDD_SERP5
Sequence: MIIVTGGAGMIGSNIIKALNDTGYRDILVVDNLKDGTKFANLVDLDIADYIDKEDFIANIIAGDDLGEIDAIFHEGACSSTTEWDGKYMMDNNYQYSKDLLHYCLDREIPFLYASSAATYGGREEFIEERQFEAPLNVYGYSKFLFDQYVREILPEAESQICGFRYFNVYGPREGHKGSMASVAFHLNGQINRGENPKLFDGSQDFKRDFIYVGDVAAVNLWFLKSGVSGIFNCGTGRAETFQAVADAVVDFHQKGAVENIPFPEKLKGRYQAFTQADLTKLRAAGYDAPFKTVAEGVKEYMAWLNRTA
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: APT_SYNJB
Sequence: MDLRALIRLVPDFPRPGILFRDMTPLLQDPAGFRAAIEQLAAGTTGMGSLDYVVGIESRGFILGAALAQHLGLGFVPVRKPGKLPPPVLSQTYSLEYGQDQLQLHAHALRPGERVLIVDDVIATGGTAAATAQLVAQSGAEVGGFAFLIELAFLSGCKALPPGIPAHVVMVEEGN
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSPB_PSELT
Sequence: MIIFEKSVPGRKAYRLPDEELQRIDPVFPEHLKRTRPLRLPELSEPDVVRHYTALAEKNYSVDKGFYPLGSCTMKYNPKLNEYVAGLEGFTDIHPYQPWESVQGALQVMYELKEFLCEITGMDEMTLQPAAGAHGELTGMLIVRAYHLSRNDKKRHVALVPDSAHGTNPASAAMAGFDVVEIKSTEDGLVDLEQLENHLNDEIAVLMLTNPNTLGLFEKDIVKIAEKVHQAGALLYYDGANLNAIMGKIKPGEMGFDIVHLNLHKTFSAPHGMGGPGSGPVGVKAFLSEFLPIPIIRKDGDKYYPDFKLPNSIGRTRSFYGNFLVLLKAYVYILSMGKDGLTRASEMAVLNANYLRSLISKFLKIASPGICMHEFVVDGSQFVKETGVKILDVAKRILDYGLHAPTVYFPLIVHEDMMIEPTETENKNTLDYFAKVLEKIVEEAKKTPEVVKTAPHTTPVKRLDDITATKKPVYRYRLS
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 2, Glycine cleavage system P-protein subunit 2, Glycine decarboxylase subunit 2, Glycine dehydrogenase (aminomethyl-transferring) subunit 2.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. C-terminal subunit subfamily.
Protein: U2AF4_MOUSE
Sequence: MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRLHNKPTFSQTIVLLNLYRNPQNTAQTADGSHCHVSDVEVQEHYDNFFEEVFTELQEKYGEIEEMNVCDNLGDHLVGNVYVKFRREEDAERAVAELNNRWFNGQAVHAELSPVTDFRESCCRQYEMGECTRGGFCNFMHLRPISRNLRRQLYGRGPRHRSPPRSHTGHRPRERNRRRSPDHRHGRF
What is the function of this protein?
RNA-binding protein that function as a pre-mRNA splicing factor.  Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection.  It can functionally substitute for U2AF1 in constitutive splicing and enhancer-dependent splicing.  Acts by enhancing the binding of U2AF2 to weak pyrimidine tracts.  Also participates in the regulation of alternative pre-mRNA splicing.  Activates exon 5 skipping of PTPRC during T-cell activation; an event reversed by GFI1.  Binds to RNA at the AG dinucleotide at the 3'-splice site.  Shows a preference for AGC or AGA (PubMed:11739736, PubMed:16819553, PubMed:18460468).  Alternative splicing of U2AF1L4 may play a role in connecting the circadian rhythm to changing external cues: may provide a circadian buffering system in central and periphery clocks that allows synchronized adaption to clock-resetting stimuli in order to prevent potentially pathogenic desynchronization (PubMed:24837677).
What are the official names of this protein?
Splicing factor U2AF 26 kDa subunit, U2 auxiliary factor 26, U2 small nuclear RNA auxiliary factor 1-like protein 4, U2AF1-like 4.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
What are the subcellular locations of this protein?
[Isoform 1]: Nucleus. Nucleus speckle. Cytoplasm. Note=Interaction with C1QBP is required for the nuclear translocation. Displays active nucleo-cytoplasmic shuttling. SUBCELLULAR LOCATION: [Isoform 3]: Cytoplasm. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm.
Protein: CSPLG_POPTR
Sequence: MALEIPKIEAILRGIAILLLVSTACLVGLDSQTKFVIVYEKEVTYKDLHALVVLVYVDAVAAAYNLLQLCRCSVSALSKGNFKGSYRYLSWACFVLDQLAAYTTFAAHSAALQHSVLGITGAKVFQWMKWCNRFTRFCFQIGGALTCGYIASVLMVMISFISAFNLFRLYSPKHFLRLKGT
What are the official names of this protein?
CASP-like protein 2C1, PtCASPL2C1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CFA70_MOUSE
Sequence: MDQTSSTTKIVHITVTNGYDLKGFKGDTPVTFVRAEFNQTVLGDSSKVTVSPEGTAKYNFTSNIDLSPDGGGALDDLAHKPLFLTVTEVLPKEKKQKDEKTLILGQAVVDLLPLLEGEESFETTVPLHPVPGSPLETPLPGSKQCSLDVKVFVAEPLLTPAQVSASNLLKVTLEAAYSVPESFIPVGPQQNYMVGLQVPSVGEKDYTMIFKNGNLKLGGEKEPVPRPKKWPIANILAPGASNIPDEFIVGGPYEEEEGELNHPEDREFRNQAECTKKRIVWDLESRCFLHPFAVASFQKRIADCRLWPVEITRVPLVVMPKAKPGKLEKIDDENQLSFHGVAYINMVPLLYPGVKKIRGAFHVYPYLDGTVFEKTKCLFSLFRDTGHHLVQNNKAGGLNSPLSKPLSKNLKEEKPGKDKDTEGRPRLGELQAPSIKSQSSDTPLESEAPLSHNLEGQQYIEAGTYIVLEIQLEKALVPKRMPEELARRVKEMIPPRPPLTRRTGGAQKAVSDYHTQIKSISRAILNEYYRMFGKQGPKLESDIDNETMEERKCQLNYELNCSGKYFAFKEQLKHAVVKIVREKYLKTTAFESQEELQTFISELYVFLVDQMHVALNQAVPDDVPSSTSTIQTSSEQLRLFAFEAEVNEKFEIAAMYYEERLVREPQNLENWLDYGAFCLLTEDNIKAQECFRKALSLNESHVDSLLLCGVLAILLENYEQAEIFFEDATCLEPTNVIAWTLLGLFYEIQNNDIRMEMAFHEAFKQLQARTLQTKLKSTVTIENMEEGVKVEPSFGPWGVVQESTTAIKTEGLSGMRPQSSHQLSPHTNMELHPQPQGPNTALSSLDEFLEESPKAQSESQEPMATGQPLEPSLVQRSSNALLKELTSKKDISKCQDSSAFSPPTQHVIAQPPVTIFMETIRFLMKVNAVQFVHRVLAHELLCPQGGPSCEYYLVLAQTHLLKKDFAKTEEYLQQAAQMDYLNPNVWGVKGHLYFLSGNHAEAKECYERTISFVVDASEMHFIFLRLGHIYLEEKEYENAKRTYMHACKRSPSCLTWLGLGIACYRLEELTEAEDALSEANALNNCNAEVWAYLALVCLKVGRQLEAEQAYKYTIKLKLKDQALLEEIHTVQEMVGFGNPSF
What is the function of this protein?
Axoneme-binding protein that plays a role in the regulation of ciliary motility and cilium length.
What are the official names of this protein?
Cilia- and flagella-associated protein 70, Tetratricopeptide repeat protein 18, TPR repeat protein 18.
What is the protein family that this protein belongs to?
Belongs to the CFAP70 family.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum. Cytoplasm, cytoskeleton, flagellum basal body. Cell projection, cilium. Cytoplasm, cytoskeleton, cilium axoneme. Note=Present all along the flagellum, with a marked signal at the base of the flagellum.
Protein: ATPG_NAUPA
Sequence: MATLKELKQKISSVKNTQKTTRAMKLVSTAKLKRAEEAIMRSREYARKIDEVMHEISAKLASVKDSIELRAFAKIENVEKVDVIVITADKGLCGGFNIQTIKQTIKLIEELKEKKVKIRLKVIGKKAIEYFKFVGIDMYEEVIGLSAAPNYEKAAELIQKSYEDFVNEEIDNIITIHNGYVNKLTQQVYVKELLPIEVDVNDSQEFLEVEPDNDYETILETLVKKYIEYSLYYALLDSLAAEHSARMQAMDAATNNAKEMVHQLTLEFNKARQEAVTRELIEIVTAIEAMKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DPRP_MYCS2
Sequence: MSDAPRGEDAVLVAVQAALAGRPGVLTGARALSHFGEHSAGWVALAAAGALAQPAKRRSWLAVGAGAFLAHAAAVVIKRVVRRERPSHPDIAVNVGTPSRLSFPSAHATSTTAAAVLLAQTTGVPAPALLVPPMALSRLVLGVHYPTDVVTGVVVGALVGKAVGKAAGRISNSVGAEGDR
What is the function of this protein?
Involved in the biosynthesis of decaprenylphosphoryl arabinose (DPA) a precursor for arabinan synthesis in mycobacterial cell wall biosynthesis.  Could be involved in the dephosphorylation of decaprenylphosphoryl-5-phosphoribose (DPPR) to decaprenyl-phospho-ribose (DPR).
What are the official names of this protein?
Putative decaprenylphosphoryl-5-phosphoribose phosphatase MSMEG_6402, DPPR phosphatase, Phospholipid phosphatase.
What is the protein family that this protein belongs to?
Belongs to the PA-phosphatase related phosphoesterase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ILVD_ACICJ
Sequence: MPQYRSRTSTHGRNMAGARALWRATGMGDADFGKPIIAIANSFTQFVPGHVHLKDLGQLVAREIEAAGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADAVEYMVNAHCADALVCISNCDKITPGMLMAAMRLNIPTIFVSGGPMEAGKYIADGETRAADLITAMVVAADPTKTDEQAAVMERSACPTCGSCSGMFTANSMNCLTEALGLALPGNGSLLATHADRKRLFVEAGWQIVDLARRYYEQDDEGVLPRRIGGFKAFENAMSLDIAMGGSTNTVLHLLAAAREAELDFTMADIDRLSRRVPNLCKVSPSVSNVHMEDVHRAGGIMGILGALDRAGLIHRDCATVHEKTIGEAIDRWDVMRGGETAKTLYSAAPGGVRTTEAFSQSRRYESLDLDREKGVIRDAEHAFSKDGGLAVLYGNIALDGAIVKTAGVDASILVFEGPARIFESQEDAVAGILGDRVKAGDVVLIRYEGPKGGPGMQEMLYPTSYLKSKGLGKSCALITDGRFSGGTAGLSIGHISPEAAQGGAIGLVEEGDIIAIDIPNRKLDVKLDEATLEARRAAMEAKGKAAWKPAARERVVSAALQAYAALTTSAANGAVRDVTQVQRGR
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: HXD4_MOUSE
Sequence: MAMSSYMVNSKYVDPKFPPCEEYLQGGYLGEQGADYYGSGAQGADFQPSGLYPRPDFGEQPFGGGGPGPGSALPARGHGQEPSGPGSHYGAPGERCPAPPPAPLPGARACSQPTGPKQPPPGTALKQPAVVYPWMKKVHVNSVNPNYTGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKGRSSSSSSCSSSAAPGQHLQPMAKDHHTDLTTL
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-D4, Homeobox protein Hox-4.2, Homeobox protein Hox-5.1.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family. Deformed subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: NDK_CHRVO
Sequence: MAIERTLSIVKPDAVAKNVIGKIYDRFESAGLKIVAAKMKQLSRAEAEGFYAVHKERPFFKDLVDFMVSGPVMIQALEGENAVLKNRELMGATDPKKAEAGTIRADFAESIDANAVHGSDSVENAAIEVAYFFAASEISSR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSH_MYCPU
Sequence: MDKMKKPKINWLLIVIVGIIAALLITVLVLLFSPKTQPKSFDYLLKHFEEAAKSTTDDIYFETIKINSLDNTIGVIFRNGAMREEYFVAASAAQANFLTSGNVEVREILQLANVQAYIQSIKTLNGTISWFTFMNKFLAQHPGYDASKAGLFGQHIVQENGFITFIKAIWFPALIAIIIFLGYKAQSRAASGGIFNPGKNQAVIVKTDKKFTDIAGNKEPIEEVQELVDYLKNPKKYAAAGARFPKGILLGGPPGTGKTLLAKATAGEANVPFFFISASSFVELYVGLGAKRVREMFKEARKLAPAIIFIDELDAVGRSRGSGIGGGNDEREQTLNQILVEMDGINENAGILIMGATNRTDVLDPALLRPGRFDRIITVGLPDIKEREEILKLHSKGKRLSKEIKFDKIAKRTPGYSGAQLENVINEASLLSVREKTDVIISTQIDEAIDRVMAGPAKKSRVISQEELKAVAYHEAGHAVVGLKVKGGNKVQKITIIPRGNAGGYNLMTPEEEKYNASKKELLATIASYMGGRAAEMIIYGKENISTGASDDISRATKIARKMVTEWGMSALGPIKYEEDTENPFLGRDYSKGTFGSKMAHEIDLEIRKIISASEEIAIKAIEQNLELLELIKDSLLENETIVAEEIEYIEKNMKLPPNNEKIKPDGESKKVNIEDLINQVNESQEKDKQKNAQIKEDLSKMDKKDNLTKAKDKGEEETLAEKAE
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: RPO5_STAMF
Sequence: MSRKKPNILEHELVPKHEVLSVREAAELLRKLKIKPAQLPWISIDDPVVKAIKAKPGDIIRIIRKSPTAGEAIAYRYVVVDTLRPRKKEKV
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo5, DNA-directed RNA polymerase subunit H.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRRT_PONAB
Sequence: MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDHGRERRSRGEYRDYDRNRRERFSPPRHELSPPQKRMRRDWDGHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPGVHIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFRRQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPGKKEEGRAGAGLGDGERKTNDKDEKKEDSKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSMSESESESESGQAEEEKEEAEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKTCSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICWNLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWASEPGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVERDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVLEWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGKKFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQSLTPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFRGQGGYPGKPRNRMVRGDPRAIVEYRDLDAPDDVDFF
What is the function of this protein?
Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation.  Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and DROSHA, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs.  Binds capped RNAs (m7GpppG-capped RNA); however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex.  Involved in cell cycle progression at S phase.  Does not directly confer arsenite resistance but rather modulates arsenic sensitivity.  Independently of its activity on miRNAs, necessary and sufficient to promote neural stem cell self-renewal.  Does so by directly binding SOX2 promoter and positively regulating its transcription (By similarity).
What are the official names of this protein?
Serrate RNA effector molecule homolog, Arsenite-resistance protein 2.
What is the protein family that this protein belongs to?
Belongs to the ARS2 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Cytoplasm. Note=Predominantly nuclear. Shuttles between the nucleus and the cytoplasm in a CRM1-dependent way (By similarity).
Protein: ODH_PSEAE
Sequence: MNAADESLGNVLLVGLGAVAIQVALDLRRHGAGRLGALNHPGRRSQRIAEALARGACLQLEGQGQHRWLSGNAALDVFHQDPAELRDDWQTLVLCVPADSYLDVVRGLPWERLGGVRTLLLVSAFIGANLLVRSALPAGCQATVLSLSSYYAATKVIDETQPLRALTKAVKRRVYLGSSRPDCPARETWRRVLAGSGVEVVPLATPEAAEGRNVTTYVHSPFFLGEFALARILSEQGPPGFMYKLYPEGPITPGAIGAMRRLWCELSELLRRMGAEPLNLLRFLNDDNYPVHETMLPRASIDGFAEAGAERQEYLLFVRYAALLVDPFSPADEQGRHFDFSAVPFRRVSRDEDGLWRLPRVPLEDYRKLALIVALAAHFDLAMPQARSLLASYENAVSRFIDCQGASQCHPSLYPIDSRPAADAIYRQWCSTC
What is the function of this protein?
Catalyzes the NAD(P)H-dependent reductive condensation of alpha-ketoglutarate to the intermediate formed by the adjacently encoded enzyme PA4836, namely (2S)-2-amino-4-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate, leading to the production of pseudopaline.  This is the last step in the biosynthesis of the metallophore pseudopaline, which is involved in the acquisition of nickel and zinc, and thus enables bacterial growth inside the host, where metal access is limited.  Therefore, this enzyme probably contributes to Pseudomonas virulence.  Can use neither pyruvate nor oxaloacetate in place of alpha-ketoglutarate (PubMed:29091735, PubMed:29618515).  Is two-fold more efficient using NADPH than NADH as the electron donor (PubMed:29618515).
What are the official names of this protein?
Pseudopaline synthase, Opine dehydrogenase, ODH, Pseudopaline dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the staphylopine dehydrogenase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RIBA_YERPS
Sequence: MQLKRVAEAKLPTPWGDFLMVGFEELATGHDHLALIFGDISGDKPVLSRVHSECLTGDALFSLRCDCGFQLEVALTRIAEEGRGVLIYHRQEGRNIGLLNKIRAYALQDLGADTVEANHQLGFAADERDFTLCSDMYKLLGIKAVRLLTNNPKKVEILTQAGINIVERVPLIVGENPKNEHYLATKAAKMGHLLTK
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: TESA_ECOL6
Sequence: MMNFNNVFRWHLPFLFLVLLTFRAAAADTLLILGDSLSAGYRMSASAAWPALLNDKWQSKTSVVNASISGDTSQQGLARLPALLKQHQPRWVLVELGGNDGLRGFQPQQTEQTLRQILQDVKAANAEPLLMQIRLPANYGRRYNEAFSAIYPKLAKEFDVPLLPFFMEEVYLKPQWMQDDGIHPNRDAQPFIADWMAKQLQPLVNHDS
What is the function of this protein?
TesA is a multifunctional esterase that can act as a thioesterase, arylesterase, lysophospholipase and protease.
What are the official names of this protein?
Thioesterase 1/protease 1/lysophospholipase L1, TAP, Acyl-CoA thioesterase 1, TESA, Acyl-CoA thioesterase I, Arylesterase, Lysophospholipase L1, Oleoyl-[acyl-carrier-protein] hydrolase, Phospholipid degradation C, Pldc, Protease 1, Protease I, Thioesterase I/protease I, TEP-I.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family.
What are the subcellular locations of this protein?
Periplasm.
Protein: Y2832_ERWT9
Sequence: MNLQHHFLIAMPTLQDPLFKRSVVYICEHNADGAMGLIVNKPMENLTVEGILKKLKIAPTAREPDIRLDKPVFSGGPLAEDRGFILHSAQKTFTSSIRVSDNTVITTSRDVLETLGTAEQPDNVLVALGYCAWEKDQLEQELLENAWLTSPANSNILFHTPIAERWREAAKSIGVDIHNIASEAGHA
What are the official names of this protein?
UPF0301 protein ETA_28320.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: RL28_NITEU
Sequence: MARVCQVTGKRPMSGHNVSHANNKTKRRFLPNLQSRRFWLESENRWIRLRLTNAALRTVDKNGIDSVVADMRARGERV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: LEU1_HAEI8
Sequence: MTDRVIIFDTTLRDGEQALKASLTVKEKLQIALALERLGVDVMEVGFPVSSQGDFESVQTIARHIKNARVAALSRAVDKDIDAAYQALKVAEAFRIHTFIASSALHVEAKLKRSFDDVVGMAVAAVKRARNYTDDVEFSCEDAGRTGIDNICRIVEAAINAGATTVNIPDTVGFCLPNEYGNIIAQVRNRVPNIDKAVISVHCHNDLGMATANSLTAVQNGARQIECTINGIGERAGNTSLEEVVMAMKVRQDFMGVDTRINTQEIHRVSQMVSQLCNMPIQPNKAIVGSNAFAHSSGIHQDGMLKNKNTYEIMSPETIGLKKEKLNLTARSGRAAVKGHMADMGYNEQDYDLDKLYDAFLKLADKKGQVFDYDLEALAFIDMQQGDEDRLVLDKLSAHSTKEYPATAFVQLKLDGEKLSTSSIGGNGPVDAVYNAILNLTGLEIKMSHYNLTAKGEGAEALGQVDIVVEHKGRKFHGVGLATDIVESSALALVHAINAIYRAHKVADIKSHKHH
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: ASSY_OCEIH
Sequence: MTKEKIVLAYSGGLDTSVAVKWLQDKYNYDVIAVALDVGEGKDLDFVKKKALDVGAIKSYVIDAKNLFAEEYVLPALQANLLYEGKYPLISALSRPLISKILVDIAEEEGAVAVAHGCTGKGNDQVRFDVSFTALNPNLKIVAPVREWAMSREEEIEYAKSHGIPIPINLDSPYSIDQNLWGRSNECGILEDPWAEAPKDAYDLTIDPVDAPEDPEVIQITFKKGKPVSIDGKEMPLDELILQLNTIAGKHGVGRIDHVENRLVGIKSREIYEAPAATTLIAAHQELEALTLPREVAEFKPTIEQKLAQTVYYGLWYSPLTEALQSFIEKTQEHVSGTVKVKLYKGHAQVIGRESENSLYDFDLATYNKADAFDHDAALGFIKLWGLPTQVHSAVNGPQGKKSIEKVDLEVKEAVKP
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_THEP3
Sequence: MKGKFISFEGIDGCGKTTQIKFLEEYLLKQGYNILVLREPGGTKVGEKVRDILLDKNNFISPVTEMLLYASSRAQLVEEKILPAIEEGKIVLLDRFVDSSYVYQGYARGLGIEKVKVVNEIATMGILPDVTIYIDITPEEAMKRRGKREADRLERESWDFHKKVREGYIKLVKEFPKRFVFIDGMQELMKVHKDIIDVVKKYL
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: FER_PHYPA
Sequence: MAAAAMTSIVPVASIAPVSKVANVRPSSVSVAKAFGLKSRSMGRLTCMATYKVTFLDGETGAENVVECSDEEYVLDAAERAGMDLPYSCRAGACSSCAGIIKAGEVDQSDQSFLDDSQIDDGFVLTCVAYPASDCIILTHQEENM
What is the function of this protein?
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
Ferredoxin, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the 2Fe2S plant-type ferredoxin family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RK16_CYCTA
Sequence: MLSPQKTKFRKQHRGRMKGVSHRRGNHICFGRFALQALEPAWITSGQIEAGRRAITRYARRGGKIWVRIFPDKPITMRPAETRMGSGKGSPEYWVSVIRPYRILYEMGGVSETVARAATEIAAYKMPIRTRFVTASPV
What are the official names of this protein?
50S ribosomal protein L16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MOAC_SALEP
Sequence: MSQLTHINAAGEAHMVDVSAKAETVREARAEAFVTMRSETLAMIVDGKHHKGDVFATARIAGIQAAKRTWELIPLCHPLLLSKVEIQLQAEPEYNRVRIESLCRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGPVRLLAKSGGKSGDFKVDAHD
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.