PharMolix/UniProtQA huggingface dataset:
Protein: MHPC_ECOLI
Sequence: MSYQPQTEAATSRFLNVEEAGKTLRIHFNDCGQGDETVVLLHGSGPGATGWANFSRNIDPLVEAGYRVILLDCPGWGKSDSVVNSGSRSDLNARILKSVVDQLDIAKIHLLGNSMGGHSSVAFTLKWPERVGKLVLMGGGTGGMSLFTPMPTEGIKRLNQLYRQPTIENLKLMMDIFVFDTSDLTDALFEARLNNMLSRRDHLENFVKSLEANPKQFPDFGPRLAEIKAQTLIVWGRNDRFVPMDAGLRLLSGIAGSELHIFRDCGHWAQWEHADAFNQLVLNFLARP
What is the function of this protein?
Catalyzes the cleavage of the C5-C6 bond of 2-hydroxy-6-oxononadienedioate and 2-hydroxy-6-oxononatrienedioate, a dienol ring fission product of the bacterial meta-cleavage pathway for degradation of phenylpropionic acid.  MhpC shows some selectivity for the carboxylate of the side chain.
What are the official names of this protein?
2-hydroxy-6-oxononadienedioate/2-hydroxy-6-oxononatrienedioate hydrolase, 2-hydroxy-6-ketonona-2,4-diene-1,9-dioic acid 5,6-hydrolase, 2-hydroxy-6-oxonona-2,4,7-triene-1,9-dioic acid 5,6-hydrolase, 2-hydroxy-6-oxonona-2,4-diene-1,9-dioic acid 5,6-hydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MhpC family.
Protein: RL9_ESCF3
Sequence: MQVILLDKVANLGSLGDQVNVKAGYARNFLVPQGKAVPATKKNIEFFEARRAELEAKLAEVLAAANARAEKINALETVTIASKAGDEGKLFGSIGTRDIADAVTAAGVEVAKSEVRLPNGVLRTTGEHEVSFQVHSEVFAKVIVNVVAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: Y4196_RHIE6
Sequence: MSPPWKLFADHLRLTVRLTPNGGRDAFDGIETGSEGETYLKARVTAIPEKGKANKALIALVSKSLGVAKSSITLVSGETARKKILRIEGDPEDLAKKLETLSG
What are the official names of this protein?
UPF0235 protein RHECIAT_CH0004196.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: BSH_CHICK
Sequence: MNLNFTSPVHPVPAPRPTSFFIEDILLHKPKPLREVPPEHFAGSLASRVPLLDYGYPLMPAPALLAPHPHPALHKPEHHHHHPYFLTTSGVPVPALFPHHAHAELPGKHCRRRKARTVFSDSQLSGLEKRFEIQRYLSTPERVELATALSLSETQVKTWFQNRRMKHKKQLRKSQDDPIHEENREQSSPEPELPEPAAAEPRKGPPGPFLLQDPEDEVDILEEGDILAAPHRL
What is the function of this protein?
DNA binding protein that function as transcriptional activator.  May play a role in the determination and function of cell types in the brain.
What are the official names of this protein?
Brain-specific homeobox protein homolog.
What is the protein family that this protein belongs to?
Belongs to the distal-less homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EGLC_ASPFU
Sequence: MQFTHLVALALALATSEAAHQGFNYGNTKSDGSAKSQADFQAEFSTAKNLVGTSGFTSARLYTMIQGGTANTPISAIPAAITEQTSLLLGLWASGGNFANEIAALKAAIAQYGDDLAKLVVGISVGSEDLYRNSVDGVKANAGIGTNPDEIVSYINEVRSTIAGTKLSGAPIGHVDTWTAWVNGSNSAVIDACDWLGFDGYPYFQNTMANSISDAKALFDESVAKTQAVAKGKEVWITETGWPVSGKTENLAVANLANAKTYWDEVGCPLFGKTNTWWYILQDADPVTPNPSFGIVGSTLSTTPLFDLSCSASSSSSAAAAASSTAGPSASSVIGGKASGFTTAAANSAKPTFTVGKGPGGSYNGTGFWNSTSSARPSSSAISGSSSGSAAGSSGAGASGASGQSSSSTGSSSAPSTSNILSNAASGLSGSIFGAVVAVCLALAAL
What is the function of this protein?
Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation.  This enzyme may be involved in beta-glucan degradation and also function biosynthetically as a transglycosylase (By similarity).
What are the official names of this protein?
Probable glucan endo-1,3-beta-glucosidase eglC, Endo-1,3-beta-glucanase eglC, Laminarinase eglC.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 17 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor. Secreted, cell wall. Note=Covalently-linked GPI-modified cell wall protein.
Protein: AROQ_BACCR
Sequence: MKKLLLVNGPNLNRLGVREVNVYGKGTLATLEADMKQEAETMGVELECFQSNHEGAIIDIIHEAEDIYEGIILNPGAFTHYSYAIRDAIASISIPVIEVHISNIHQRESFRHESVTAAVCAGQIVGFGFYGYKLALFALMEKLREA
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: HUTH_SALPA
Sequence: MNTMTLTPGQLSLSQLYDVWRHPVQLRLDASAIDGINASVACVNDIVAEGRTAYGINTGFGLLAQTRIADEDLQNLQRSLVLSHAAGVGDPLDDAMVRLIMVLKINSLARGFSGIRLSVIEALIALVNAGVYPLIPAKGSVGASGDLAPLAHLSLTLLGEGKARWQGEWLPAQAALKKAGLEPVALAAKEGLALLNGTQASTAFALRGLFEAQELFASAVVCGALTTEAVLGSRRPFDARIHAARGQQGQIDAARLFRHLLTDTSAIAESHHHCHKVQDPYSLRCQPQVMGACLTQLRQTKEVLLAEANAVSDNPLVFADAGEVISGGNFHAEPVAMAADNLALAIAEIGALSERRIALMMDKHMSQLPPFLVKNGGVNSGFMIAQVTAAALASENKALAHPHSVDSLPTSANQEDHVSMAPAAGRRLWEMAANTRGIIAVEWLAACQGIDLREGLTSSPLLEQARQTLRERVAHYTQDRFFAPDIECATTLLAQGALQRLLPDFM
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_CHLPD
Sequence: MLRYKRILLKLSGEALAGEDGYGINAQMLERYAEEIREVRNLGAEVALVIGGGNIFRGVSEAAANMDRVQADYMGMLATVINAIAFQDALERKGVFTRLQTAIKMEQMAEPFIRRRAIRHLEKGRVVIFGAGTGNPYFTTDTAASLRAIEIEAELIVKGTRVNGVYDSDPEKNPDAVFYPKISYQDVIRKNLRVMDMTAITLCRENLLPIVVMNMNESGNFSRLLCGEEIGTLVHA
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_DECAR
Sequence: MGTVLAFDFGEKRIGVATGETMLCSAHPLTTIHAESNEDRFAAIGKLVAEWQPEQLVVGLPTHADGTPHEMTRLATKFGERLARRFNLPVSFADERLTSLDAEARLRETGRNSKSAKPLLDAVAAQLILQTWFESPHHVIPTQPSA
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTHS_GRABC
Sequence: MSTEANKPRGNQHQEAKSDAEIAQAAFMRPIVDVAAEKLGIAAEHLAPYGHYKAKIDLNYLSSLDSRPDGKLVLVTAISPTPAGEGKTTTTVGLTDALNHIGKKAVACLREPSLGPCFGVKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAALIDNHVYWGNELGIDPRRIGWRRAVDMNDRALRSIVSSLGGVSNGYPREDGFDITVASEVMAIFCLATDLDDLQRRLGNIIVGHTKDRKPIRASELSAAGSMAVLLKDAIAPNLVQTLEHNPAFIHGGPFANIAHGCNSVIATRAALKLSDYVVTEAGFGADLGAEKFFDIKCRKAGLSPSAVVIVATVRALKMHGGVAKDALKTENVEAVQKGFANLERHIQNVRKFGVPVVVGVNKFSADTDAEFQMLHDLCAKMGVPCVSSDHWANGGAGAADLAHEVVKLVEGGSADFKPLYPEDMPLWDKLRTIATEIYGASDITADAAVRKRFDELQKEGFGHLPICVAKTQYSFSTDANLRGAPSGHVIPVRDLRLSAGAEFVVAICGDIMTMPGLPKVPAANAIRLASNGTIAGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: RBS5_ACEAT
Sequence: MAAAMMNKSVLLNKQCGKPAAVPKVVMSKGGFARTSAVNKNRDMMVWQPFNNKMFETFSFLPPLTDEQISKQVDYILANSWTPCLEFAASDQAYAGNENCIRMGPVASTYQDNRYWTMWKLPMFGCTDGSQVLSEIQACTNAFPDAYIRLVCFDANRQVQISGFLVHRPPSATDYRLPADRQV
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, chloroplastic 5, RuBisCO small subunit 5.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RSMJ_ACTP7
Sequence: MTIQLINESSNTEKFQQICDKWRLVHDRSAILALVLTDERLELRKLDEPKLGAIAVNFVDGTMAHRRKFGGGRGEAVAKAVGIKGDYLPTIIDATAGLGRDAFVLASVGCKVLLVERNPIVAALLEDGLVRAYADPEIGAFMQERMILADVRNISLLDVAQQAADVVYLDPMYPHKQKSALVKKEMRVFQHLVGADLDSDNFFVPAKALARKRVVVKRPDYAPFLAEQKPDFSQTTKNHRFDVYLSHLKSA
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_BRASO
Sequence: MKTFSAKPAEVQKKWVVIDAKGLVVGRLATLVAMRLRGKHLPIYTPHVDCGDNVIIVNAKHAVFTGRKREQKTYYKHTGFVGHVKERTARQILEGRFPERVLEKAVERMIPRGPLGRVQMGNLRVYGGPDHPHEAQNPEKIDIAKLNRKNTRAA
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: ISDA_STAAN
Sequence: MTKHYLNSKYQSEQRSSAMKKITMGTASIILGSLVYIGADSQQVNAATEATNATNNQSTQVSQATSQPINFQVQKDGSSEKSHMDDYMQHPGKVIKQNNKYYFQTVLNNASFWKEYKFYNANNQELATTVVNDNKKADTRTINVAVEPGYKSLTTKVHIVVPQINYNHRYTTHLEFEKAIPTLADAAKPNNVKPVQPKPAQPKTPTEQTKPVQPKVEKVKPTVTTTSKVEDNHSTKVVSTDTTKDQTKTQTAHTVKTAQTAQEQNKVQTPVKDVATAKSESNNQAVSDNKSQQTNKVTKHNETPKQASKAKELPKTGLTSVDNFISTVAFATLALLGSLSLLLFKRKESK
What is the function of this protein?
Cell wall-anchored surface receptor that participates in the extraction of heme from oxidized methemoglobin/metHb to enable growth on hemoglobin as a sole iron source (By similarity).  Receives heme from IsdB and transfers it to IsdC (By similarity).  Also plays a role in the inhibition of host immune response.  Protects S. aureus against the bactericidal protease activity of apolactoferrin.  Decreases bacterial cellular hydrophobicity, which renders S. aureus resistant to bactericidal human skin fatty acids as well as to beta-defensins and cathelicidin.  Also binds fibronectin and chains B-beta and gamma of fibrinogen, promoting clumping of S. aureus with fibrinogen.  Involved in adherence of S. aureus to human desquamated nasal epithelial cells and is required for nasal colonization (By similarity).
What are the official names of this protein?
Iron-regulated surface determinant protein A, Fur-regulated protein A, Staphylococcal transferrin-binding protein A.
What is the protein family that this protein belongs to?
Belongs to the IsdA family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor. Note=Encodes an LPXTG motif-containing sorting signal that targets to the cell wall, which is catalyzed by sortase A.
Protein: SNU71_CANGA
Sequence: MLEDALVPDDKLIYVSPENLYYCYANDTIDQDDKWTSIQPQQGYIPILSANLRAYKIELLKKLRFSGQNNVSPSIKKEKKNLEPNKKITTKPTESTGSKKYLIPEQFIPDSLEKQLRTLTVILKDALYLGKNNRFIKENEVVSDDTRLLILDEFLKLIIPNYIDSLANWTLVDLNKGTDDESLLYLRFNESGTQSMISFYKKHSKMAKYMEIHYDTNTEKYINDNFKDDGDEDNVEAEQSHSVGEILKSMETAFEKARSQVGTFKGDINDDQDDKINYKIDYNTLLDIPSDSLEQLTKEILNFRTKVIDIEKQKQLRQQYEDNERRQKHMTQLFEKLRKGTKSNDSNRNMDIESTDTINDSDSEEDDDEEDEDDLAIEKRKEEKRKEEEARKYRALLKDYETTIEPHLHLLSQQYKQNLEYEKELAANREANVKDLLRQANDIYYDKDRSFKDREEQEDKLDREKYGDIIIEDIVIDDDRKGQKKLLEKDKKVKKAGEPAIKINLAFKKAMDNSIQDKRDKAEDIEPVSQPIEARSTNRYAALKEKRVVDELVKELLGVYEDDVVAYVFEILEKPEMSDEKKQSELVTEMEDLFDKEGAVQFAEQVFKALDEA
What is the function of this protein?
Component of the U1 snRNP particle, which recognizes and binds the 5'-splice site of pre-mRNA.  Together with other non-snRNP factors, U1 snRNP forms the spliceosomal commitment complex, that targets pre-mRNA to the splicing pathway (By similarity).
What are the official names of this protein?
U1 small nuclear ribonucleoprotein component SNU71.
What is the protein family that this protein belongs to?
Belongs to the SNU71 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DPOZ_SCHPO
Sequence: MRFSIEYIDWELSPCDPAYDFVGKDLPTANEELTTVPVIRVFGLNEEAETVCCFIHNVFPYIYVEYSSFAETLDLEVPDFLSQLQTSINYALALAARANPETYKPAVQSVQLVKGIPFYGYSFCFQKFLKICLFSPKNRDRLVDLFRQGAILNKVIQVYESHLPYLLQFMVDHNLYGCAPIDLDDSIIKRDDLLSFCNVEVHVSPNAILNACWLSERNIHTDLYETHASSPNSLLVTSLAEIWKSEASRRNLTSSDETNSFSKLHQSQFGLKEESSHEPRSSQHWKNEVAMKDLLKNLIKSKLESSSDVNTPLIFDPWPELPTIYSAIHTKDYVRPSQNDISVSQISVDEKICTSYESLPKIQLEQNTAPVIESSFEQLDSELERILGDTLFDSFPYVEPNVDRSKFPKSPLNSSQEVTIHSSQDRQSPPSSPLKDVPSQINPFSPSLRLKGGSPITKREIEFCRDLPNRPTSSEPNQGDTRKAGKRLKYSRNLDDYHICTQIPEDYSPKFLSQHESFVYKQQPPSTDDLYGTMKKLKIPFSIPTNVHYSSEKDIPSYSQEYLGKSHYPIGVSSRYLPEFQSDGSVSEKVRLNPLKLSNFHGERTWQYIKPAPLAVDLSNLESKEAVSEEIQSPQRLSRSKVFRKDPYSCVRILALELFCCSHGGLTPDPTKDSIECCFWAYQEDVNSSMIDRVGFIVVDKSASNSSFGRSFPSCTVLVVNSELELINEVIGLNRQLDPTIVCGYEVHNSSWGYLIERASYRFNYDLPEQLSRLKCTSKANFAKKENAWKYTTTSSINIVGRHVLNIWRILRGEVNLLNYSLENVVLNIFKKQTPYYNQADKVHLWQSSRFHEKQILLNYMLNRTRYCLEILSACAIVTKIREQARIIGIDFMSVISRGSQFKVESIMFRIAKPENYIFPSPSAKQVAEQNALEALPLVMEPKSDLYNNPVVVLDFQSLYPSIIIAYNLCYSTCLGPVKIVNGKVKLGFMFHSSNPNIVNLIKNDVYISPNGYAYVKENVRKSLLAKMLEELIETRNMVKRGMKDCDSDYVNKVLNSRQLALKLIANVTYGYTSASFSGRMPCSEIADTIVETGREILSYSLEYINTLDFCHAKVVYGDTDSLFVELPGATKEQAFDIGQQLANNITSRFPSPIRLKFEKIYFPCFLLAKKRYVGFKFESVSQKAPIFEAKGIETVRRDGTPVQQQLLRRCLEILFKTKDLSTVKKEFQNVCYQIMSGNVPVMDFCFSKEVRLEKYKELSTAPPGAVMARRLMTKDPRREPQYGERVPYLIIAAAPGTTLANRSVAPEEFLSSSFSQLDINYYINNSLIPPLDRFLNLLGASAQSWYHEMPKPRTSLKLTETVKGGIQKKTLDTFLMEKLCSSCLKNNIEIIPDKINSLCSDCLKNPCATISKAVTQHNAYNKKLSLLFDICRGCSKLSSSDPVLCKSNSCKVYYDRAKTENYAKVQAEMLTKTLGSLDW
What is the function of this protein?
Nonessential DNA polymerase.  Required for DNA damage induced mutagenesis.  Involved in DNA repair, mitochondrial DNA repair and translesion synthesis.  Has a role in the bypass of abasic (AP) sites (By similarity).
What are the official names of this protein?
DNA polymerase zeta catalytic subunit, Protein reversionless 3.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Mitochondrion. Nucleus.
Protein: YK15_SCHPO
Sequence: MKRQRPQDSMISVPLQNENSTTTPTKEVSHLNFPLKRPRLHSFVPTSKQAALSDITPDTPPAFKTPYSSLPYNLVPQNSSTSKKRPRAEDLLVIEPSQNSLVPSTQNNEWNEIARKRVSLESDHPDKSGQVIDLATGQILDKQTEDIDDDRNKSAVSKSLVRHPHRLKMLPFGIQSAHPYISSLNSNYPTTWHFASHYYPTDSKQLVKYHPTEVHPSWTVEEPVHYNTYDGVVNEPNSSVIIEELDDDYDELNDPMNNNDTPITNSTHSAQMSNLPTHDSMDIDMGGAVPSTST
What are the official names of this protein?
Uncharacterized protein PB1A10.05.
What are the subcellular locations of this protein?
Nucleus.
Protein: NDHI_VILAC
Sequence: MFPMVTEFMNYGQQTVRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSIIDDYTIRTILNLPEIKT
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: NRAM1_CHICK
Sequence: MSGSGPAMASLEPGLAGSLNRGQTDASNVPVPPHHPVPHAQTYLDELISIPKGSTPGFSFRKLWAFTGPGFLMSIAYLDPGNVESDLQCGAVAGFKLLWVLLWATVLGLLCQRLAIRLGVVTGKDLAEICYLYYPRVPRVLLWLMMEIAIIGSDMQEVIGTAIAFSLLSAGRIPLWGGVLITITDTLFFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVMVRPAQTEVLKGIFLPYCPGCGREELLQAVGIVGAIIMPHNIFLHSSLVKTRAIDRSKKEEVKEANMYFLTESCLALFVSFLINLFVMAVFGEAFYHQRNEDVHNKCVNSSVSRYASIFPINNETVSVDIYQGGVILGCYFGAAALYIWAVGILAAGQSSTMTGTYAGQFVMEGFLQLRWSRFTRVLFTRSLAILPTLFVAAFRDVSQLTGMNDLLNVLQSILLPFAVLPVLTFTSLRPLMHDFANGLLGQVLMSLITGLVCAINVYFVVDFLPTLRGLGYLIPLGLLLVAYVAFVTYLLWTCSIAHGARFLARGRYNRFSFDVTADVPGLAGPH
What is the function of this protein?
Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens.  Macrophage-specific membrane transport function.  Controls natural resistance to infection with intracellular parasites.  Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis of its protective enzymes (By similarity).
What are the official names of this protein?
Natural resistance-associated macrophage protein 1, NRAMP 1, Solute carrier family 11 member 1.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: LRK15_ARATH
Sequence: MSKGLFLIWLISSFHLISFSTSSKDTSFVFNGFGQSNLALDGSATLLPNGLLQLAKDSQHQMGHAFIKKPIDFSSSKPLSFSTHFVCALVPKPGFEGGHGITFVISPTVDFTRAQPTRYMGIFNASTNGSPSSHLFAVELDTVRNPDFRETNNNHIGIDVNNPISVESAPASYFSKTAQKNVSINLSSGKPIQVWVDYHGNVLNVSVAPLEAEKPSLPLLSRSMNLSEIFSRRRLFVGFAAATGTSISYHYLLGWSFSTNRELSQLLDFSKLPQVPRPRAEHKKVQFALIIALPVILAIVVMAVLAGVYYHRKKKYAEVSEPWEKKYGTHRFSYKSLYIATKGFHKDRFLGRGGFGEVYRGDLPLNKTVAVKRVSHDGEQGMKQFVAEVVSMKSLKHRNLVPLLGYCRRKGELLLVSEYMPNGSLDQHLFDDQSPVLSWSQRFVILKGIASALFYLHTEAEQVVLHRDIKASNVMLDAELNGRLGDFGMARFHDHGGNAATTAAVGTVGYMAPELITMGASTITDVYAFGVFLLEVACGRKPVEFGVQVEKRFLIKWVCECWKKDSLLDAKDPRLGEEFVPEEVELVMKLGLLCTNIVPESRPAMGQVVLYLSGNLPLPDFSPYTLGIGSFTPVVVDAASLTVSFTSRNWSAPSASSSSANNSKDHEQPLEFKS
What are the official names of this protein?
Probable L-type lectin-domain containing receptor kinase I.5, LecRK-I.5.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the leguminous lectin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: YREP_STRAM
Sequence: MDPQTAATLLPLLGWALHGSVLTRRLASARRDPLTGLHTRAGWTARAEHCIHRHPRAAVLLVDLDHFKTLNDTHGHAAGDAALIATAHRLSSWCGRHGTAGRLGGDEFVTAIRDLDAVDLDALTTALHQPTNYDGTALPLAASVGVCRVAELPVPALTDALAAADAAMYAAKGRSRRGSRPAR
What is the function of this protein?
Might be involved in pSAM2 replication control.
What are the official names of this protein?
Uncharacterized 19.3 kDa protein in repSA 5'region, ORF183.
Protein: CLPP_CAPBU
Sequence: MPIGVPKVPFRSPGEGDTSWVDIYNRLYRERLFFLGQEVDTEISNQLISLMIYLSIEKDTKDLYLFINSPGGWVISGMAIYDTMQFVRPDVQTICMGLAASIASFILVGGEITKRIAFPHARVMIHQPASSFYEAQTGEFILEAEELLKLRETITRVYVQRTGKPIWVVSEDMERDVFMSATEAQAHGIVDLVAVQ
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: HDFR_YERPY
Sequence: MDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLENQLGANLFTRHRNNIRLTPAGERLVPYAEMLLNTWRLAKKEVIHSLQHTELSIGATASLWEAYLTPWLQQLYEQQEELRLEARIALRNSLVKQLHERQLDLLITTEPPKMDELACLLLGHFSLRLYSSFSLDLPKEDDTPNEHKNASEVPYIKLEWGADFHQQENRLLDSEQAPILTTTSAHLTRQLLETTGGCAFLPEHWQKEYPQLVIHPDIPPIVRPLYAVWLQNSDQQALIRQLLKTPMNNATQSVTRE
What is the function of this protein?
Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.
What are the official names of this protein?
HTH-type transcriptional regulator HdfR, H-NS-dependent flhDC regulator.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: RS20_STRU0
Sequence: MANIKSAIKRAELNVKANEKNSAQKSAMRTAIKAFEANPTEELFRAASSSIDKAESKGLIHANKASRDKARLAAKLG
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: UBP18_PONAB
Sequence: MSKAFGLLRQTCQSILAESPQSPADLEEKKEEDSNMKREQPRERPRAWDYPHGLVGLHNIGQTCCLNSLIQVFVMNVDFARILKRITVPRGADEQRRSVPFQMLLLLEKMQDSRQKAVRPLELAYCLQKYNVPLFVQHDAAQLYLKLWNLMKDQITDVHLVERLQALYMIRMKDSLICLDCAMESSRNSSMLTLPLSLFDVDSKPLKTLVGQEDALHCFFQPRELSRKSKCFCENCGKKTHRKQVLKLTHFPQTLTIHLMRFSIRNSQTRKICHSLYFPQSLDFSQVLPTKQKSCDAEEQPGGQFELFAVIAHVGMADSGHYCVYIRNAVDGKWFCFNDSNICLVSWEDIQCTYGNPNYHWQETAYLLVYMKMEC
What is the function of this protein?
Interferon-induced ISG15-specific protease that plays a crucial role for maintaining a proper balance of ISG15-conjugated proteins in cells.  Regulates protein ISGylation by efficiently cleaving ISG15 conjugates linked via isopeptide bonds.  Regulates T-cell activation and T-helper 17 (Th17) cell differentiation by deubiquitinating TAK1, likely to keep TAK1-TAB complexes in steady conditions.  In turn, restricts activation of NF-kappa-B, NFAT, and JNK as well as expression of IL2 in T-cells after TCR activation.  Acts as a molecular adapter with USP20 to promote innate antiviral response through deubiquitinating STING1.  Involved also in the negative regulation of the inflammatory response triggered by type I interferon.  Upon recruitment by STAT2 to the type I interferon receptor subunit IFNAR2 interferes with the assembly of the ternary interferon-IFNAR1-IFNAR2 complex and acts as a negative regulator of the type I interferon signaling pathway.
What are the official names of this protein?
Ubl carboxyl-terminal hydrolase 18, ISG15-specific-processing protease, Ubl thioesterase 18.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
Protein: HPCH_SHIB3
Sequence: MENSFKAALKAGRPQIGLWLGLSSSYSAELLAGAGFDWLLIDGEHAPNNVQTVLTQLQAIAPYPNQPVVRPSWNDPVQIKQLLDVGTQTLLVPMVQNADEAREAVRATRYPPAGIRGVGSALARASRWNRIPDYLQKANDQMCVLVQIETREAMKNLPQILDVEGVDGVFIGPADLSADMGYAGNPQHPEVQAAIEQAIVQIRESGKAPGILIANEQLAKRYLELGALFVAVGVDTTLLARAAEALAARFGAQATAVKPGVY
What is the function of this protein?
Catalyzes the reversible retro-aldol cleavage of 4-hydroxy-2-ketoheptane-1,7-dioate (HKHD) to pyruvate and succinic semialdehyde.
What are the official names of this protein?
4-hydroxy-2-oxo-heptane-1,7-dioate aldolase, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, HHED aldolase, 4-hydroxy-2-ketoheptane-1,7-dioate aldolase, HKHD aldolase.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family.
Protein: RNPH_RHOE4
Sequence: MTTREDGRADDELRTVKITRGFTSHPAGSVLVEFGNTRVMCTASVEEGVPRWRKGSGLGWLTAEYAMLPAATHTRSGRESVKGKVGGRTQEISRLIGRSLRACIDLAAIGENTIALDCDVLQADGGTRTAAVTGAYVALVDAVTYLRAADLLSDPQPISCGIAAVSVGVVDGRVRLDLPYEEDSRAEVDMNVVATDTGTLVEIQGTGEGATFPRSTLDKLLDSALAGCEQLFEIQRQALAEPYPGVLPEPKNPEPKKKFGA
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.