PharMolix/UniProtQA huggingface dataset:
Protein: EX7S_RHOP5
Sequence: MADPADVKKLSFETAMEELESIVKRLEDGKVPLEESVAIYERGEALKRRCEELLRTAEARVDKITTDAAGQPTGTAPLDVE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACT_PLAMG
Sequence: MCDDEVAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNAPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPESLFQPSFLGMESAGIHETTYNSIMKCDVDIRKDLYANTVLSGGTTMFPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin, adductor muscle.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: NF09_NAEFO
Sequence: ATSAAQGAALDESVRKVLKP
What are the official names of this protein?
Unknown protein NF009 from 2D-PAGE.
Protein: RS1_ECOLI
Sequence: MTESFAQLFEESLKEIETRPGSIVRGVVVAIDKDVVLVDAGLKSESAIPAEQFKNAQGELEIQVGDEVDVALDAVEDGFGETLLSREKAKRHEAWITLEKAYEDAETVTGVINGKVKGGFTVELNGIRAFLPGSLVDVRPVRDTLHLEGKELEFKVIKLDQKRNNVVVSRRAVIESENSAERDQLLENLQEGMEVKGIVKNLTDYGAFVDLGGVDGLLHITDMAWKRVKHPSEIVNVGDEITVKVLKFDRERTRVSLGLKQLGEDPWVAIAKRYPEGTKLTGRVTNLTDYGCFVEIEEGVEGLVHVSEMDWTNKNIHPSKVVNVGDVVEVMVLDIDEERRRISLGLKQCKANPWQQFAETHNKGDRVEGKIKSITDFGIFIGLDGGIDGLVHLSDISWNVAGEEAVREYKKGDEIAAVVLQVDAERERISLGVKQLAEDPFNNWVALNKKGAIVTGKVTAVDAKGATVELADGVEGYLRASEASRDRVEDATLVLSVGDEVEAKFTGVDRKNRAISLSVRAKDEADEKDAIATVNKQEDANFSNNAMAEAFKAAKGE
What is the function of this protein?
In case of infection by bacteriophage T4, plays a significant role in substrate choice by viral endoribonuclease RegB.
What are the official names of this protein?
30S ribosomal protein S1, Bacteriophage Q beta RNA-directed RNA polymerase subunit I, Small ribosomal subunit protein bS1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX2_ORYSJ
Sequence: MILRSLECRFLTIALCDAAEPWQLGSQDAATPMMQGIIDLHHDIFFFLILILVFVSRMLVRALWHFNEQTNPIPQRIVHGTTIEIIRTIFPSVIPLFIAIPSFALLYSMDGVLVDPAITIKAIGHQWYRSYEYSDYNSSDEQSLTFDSYTIPEDDPELGQSRLLEVDNRVVVPAKTHLRMIVTPADVLHSWAVPSSGVKCDAVPGRSNLTSISVQREGVYYGQCSEICGTNHAFTPIVVEAVTLKDYADWVSNQLILQTN
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: YKID_ECOLI
Sequence: MTQRPWSKLQRKTHNIAALKIIARRSE
What are the official names of this protein?
Protein YkiD.
Protein: FAR5_HIRME
Sequence: GGKYMRF
What are the official names of this protein?
FMRFamide-like neuropeptide GGKYMRF-amide.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: YTOA_BACSU
Sequence: MIYPYKEHKPDIHPTAFIADNATITGDVVIGEQSSIWFSVVIRGDVAPTRIGNRVNIQDLSCLHQSPNKTLLIEDDATIGHQVTLHSAVIRKNALIGMGSIILDGAEIGEGAFIGAGSLVPPGKIIPPGHLAFGRPAKVIRPLTEEDRKDMQRIRSEYVEKGQYYKFLQQT
What are the official names of this protein?
Uncharacterized transferase YtoA.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: PEX11_YEAST
Sequence: MVCDTLVYHPSVTRFVKFLDGSAGREKVLRLLQYLARFLAVQNSSLLARQLQAQFTTVRKFLRFLKPLNHLQAAAKFYDNKLASDNVVRVCNVLKNIFFAAYLSLDQVNLLRILKVIPVTVLTGKKIPRWSNWCWLFGLLSGLAMDLRKIQTSHAQIAAFVKAKSQSQGDEHEDHKKVLGKAYQDRYTALRRLFWDAADSFIVLNNLGYLSSNEEYVALSGVVTSILGMQDMWKAT
What is the function of this protein?
Involved in peroxisomal proliferation.  Promotes peroxisome division and biogenesis.
What are the official names of this protein?
Peroxisomal membrane protein PMP27, Peroxin-11.
What is the protein family that this protein belongs to?
Belongs to the peroxin-11 family.
Protein: DEXT_ARTGO
Sequence: MPGTGLGRLAKHVTAAAAVFLISTGAVLPAQAETAPGSTPSAAPAASVEKHPITTANNGNLHTWWHDNGVFSPAAPTQSDEVRRSSLYDVRVAQANQPQKAYDAFTYMSIPRSGKGKIGYTEEDGAEFSSEAGLTMSWSSFEYAKDVWVEVSLRTGQTISSADQVQIRPSSYNFEKQLVDADTVRIKVPYSDAGYRFSVEFEPQLYTAYNDMSGDSGKLTTEAEGNRPIHTEPRNSMMVFAEPKLRGEQKERLVPTQESGSIHYPEPGEVRNLNSVSAEIIYFRPGTYSMGSDYHAVLPANVKWVYLAPGAYVKGAFRFLHDTQSQYKVTGYGVLSGEQYVYEADTNNSYNHLSGASNCHSSCVKMLQFASADAEQKLDLQGVTVAEPPYHSFVVYGNEQTFHMNVENYKQVGSWYWQTDGIELYQGSTMKNTFFNANDDVLKMYHSDVSIDNTVVWKNENGPVVQWGWTPRNIDNVNVTNTTVIHNRMYWKDVKYNTCIFNSSSHWEDMGSTTKADPNTTVKNMRFENTTVEGMTNCAIRVYALSDTENIHIKNFNIGSWNGLDWTSQVSHLKRYTNSAGEKVTIGNELPDGNGLAIENYSVGGQVIEKSGGNWSDYQLGRLGFDGENWDSWNAWKSAP
What are the official names of this protein?
Dextranase, Alpha-1,6-glucan-6-glucanohydrolase, Endodextranase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 49 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL361_ECOUT
Sequence: MKVRASVKKLCRNCKIVKRDGVIRVICSAEPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: SYC_CLOK5
Sequence: MRIFNTMTRRKEEFVPLIPGEIKMYVCGPTVYNFFHIGNARTFVVFDTVRRYFEYKGYKVNFVQNFTDIDDKMIKKANDENITVQQLGDRFIDEYYRDADALNIKRATVNPRATLYISKIIEFIQDLIDKGYAYSVDGDVYFNAKKFNNYGKLSGQNIEQLQSGARIDIDERKKNPMDFAVWKSEKKGEPSWESPWGMGRPGWHIECSCMAYNILGETIDIHAGGSDLKFPHHENEIAQSEGRTGKVFAKYWMHSAFVNINNQKMSKSLNNFFTTREILDKYEPDVIRLFMLSGHYRTPINFSIELLDSTKSALDRICNSIINLEELSSKVKNDGILDSEIKYKEHLNSYKQRYIEKMDDDFNTADAISVIFDLIRDINTNIDENSSMEIIKYSLALIRELGSPLGILQKSKRGSIETEVELLIEKRQKARKDKNWALADKIRDDLKDKGIILEDTSDGVRWKRV
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCA_STAAN
Sequence: MDKSLFEQARPILEQIQDNGFEAYYVGGSVRDYVMGRNIHDIDITTSATPDEIESIFSHTIPVGKEHGTINVVFNDENYEVTTFRAEEDYVDHRRPSGVTFVRDLYEDLQRRDFTMNAIAMDTAYKLYDYFDGQQDINNRIIRTVGIAEERFQEDALRMIRCLRFQSQLSFDIAMETFEAMRTQMADIKFLSIERIVIELTKLMRGINVEESFNHLKSLKAFNYMPYFEQLDMNQINVTEPIDLELLIAIVSVKFDINYSLKPLKLSNRQVKDINQYIQIMNALPSIITKEQLKMFVYDYDTNLIKNVMVAADVLKANDIQGHEPLIVNLQTIDETLHRLPMHNRKDMMVNGGVLMAHLNAKSGPWLKDVLRQIEIAIVTGKVSNEETEILKWVDNHVKI
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
Protein: PANB_VIBCH
Sequence: MKKITINDLMKWKQEGRKFATSTAYDASFAQLFESQEMPVLLVGDSLGMVLQGETDTLPVTVDDIAYHTRCVRKGSPNCLLMADMPFMSYATPEQACENAAKLVRAGANMVKIEGGDWLVDTVKMLTERAVPVCAHLGLTPQSVNIFGGYKVQGREQDKADRMVRDALALQEAGAQIVLLECVPAELANRITQILDVPVIGIGAGNGTDGQILVMHDMFGISANYMPKFSKNFLAETGDIRQAVAKYIEDVASGAFPDLAHTIA
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YNFC_SALPC
Sequence: MKKPLLLTLLCMILAGCDNPKSLESFTPEMASFSNEFDFDPLRGPVKDFSQTLMSENGEVAKQVTGTLSQEGCFDTLELHDLENNTELALVLDANYYRDAQTLEKKVQLQGKCQLAALPSAGVTWETDDNGFVVSATGKEMKVEYRYDSEGYPLGKTTINSQNTLSVTAKPSADPRKKLDYTAVSRVDDRQVGNVTLSCEYDAYANPVDCRLVIVDESVKPAVSHHYTIKNRIDYY
What are the official names of this protein?
UPF0257 lipoprotein YnfC.
What is the protein family that this protein belongs to?
Belongs to the UPF0257 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: LIPA_UNCRE
Sequence: MAVCARGLRCLGTPAVSLRLAASRSYATTTPPDPAIPNTPGAAATSSPAKRPRTSFQDKLNAGPSFSDFLSDKDDARILDPAEAYALKTALVGPKGKKKEYTRLPPWLKTSIPDSNNYKRIKNDLRGLNLHTVCEEARCPNISECWGGGSKSAATATIMLMGDTCTRGCRFCSVKTSKAPPPLDPHEPENTAEALSRWGLGYVVMTSVDRDDLPDGGARHWAETVMKIKQKAPNILVECLTGDFDGNLEMVALVAKSGLDVYAHNVETVEALTPQVRDRRAGFQKSIRVLKAAKAAQPSLITKTSMMLGLGETEEQMWDALRQLRAADIDVVTFGQYMRPTKRHMPVHEYVRPDVFEFWKEKALEMGFLYCASGPLVRSSYKAGEAFIENVLKKRRAESTGPGSASVQDVATGDLVR
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, mitochondrial, Lipoate synthase, LS, Lip-syn, Lipoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TIM_CAEEL
Sequence: MNVLVQGAVHALGYYEDGKYSREPDCYESIRDLIRYLREDGDDHTARIECGRHNLVEQDLVPMVKCEDLTDDEFDIAIRLMVNLCQPAISTMRGKPPADRDQWKMYWELEENLRRAKTAFSDAHFFTAIKKRIDNYFIDTEYEDRDERLRLVVERIVLLIKYVFSINPDTSEGRRTRIEDSSHDRVIIAFLESGIDKTLMHIANQPREKEFHVTILDIFALILKEQTAEDLATKSEEVSTAEQKKTEEEFRKIIENHVVKETQKRKSFSRFGGSYTIKGLKGISANSSQVVFKPIQNVEKHNFLDDRKAKKRAPRNRRPFEIDTNSHFASSEVRGMLRDMVIRIIETCFNRLMKSSKTTVFVQVQKTSQINYFFLIKFVLRFVRLSRQDHLLERISECIGVEAFHENNVQLTEYVENATTLKGVEAKSHGLKAQYALGAYNELVLLHRYIYEHAKEENERKFAKRALEHIVNVEEYRELPIFIIKKFSSSVLSNNFLRELVLTTHHYMKLVERFVKTGALKKVTKKVKVRKATKKSKMSEEDVRSEFDGMSKKDLDRLWEESKGLVLQILKKEVPEMRGMNPIDSQLDVPVDAQQKFAKLSIQRSLRSRGFPAAVGLYHASRALWPESFKRGLTDFQDSPGEEDQLQELEQLLKADMKKVAKDLKKAESCKTCDEDPAYKKYDKMDATALQSLWEQSTDTLARILSHELPESESTSPVNWQLDITPDVQQKFAMLAIQRALRARDLPAAVGLYHTSRKLWPGDEAIFGAPGIGVEEEIAELKAILEADLHEVAREMKVAEDRAEDPDEEDPAEPYDSEQEEEEEVPAWKVEEIDFQFDSYVCKFSNVDVLKWYVFLLNDFSKNSTELNQALVKMLHRIAFDLKLPIKLYQVSLFQVFSKVNEHFTHLSKDLRKSSRLYELYQFGFHLLKKFFSKFTGDLAIEALFWKGPRECFEIENGYGSWVKSREADIRVWTEDLEIELRNLYEEYRTMETRDGIDVLDFIEHNLSRARSRKKVAKKLIEFGFDLLGAKWKNSDKARMDSVLPIGDIQKWYDEWKEAGARGDLVNVLQEKLNEDLGMEISRKKILKQLAHMDILYEKPKKEKPLPQWDTGLIEELKKLKEQYDDIPDALNMLGVNIVRYVMKRLSEKKPTRQVERHLESLGATIPERSKKSEKNGKKFDDFLNDDDDDSENDVGGGSEDDEEEEIVMKSKRIIPDSEDEEEHIEQEEAQKKLEKVAEKPNTLMGMIAGRKRKLAQLESDSSDESDDDDSAEKEEKKLPAAEDDSDLEEDAVIYKRSYVDALLTGGSIAGNGITETRRDTSEEREDDDDEDPFTKKLTFKRRIVMSDNEDEA
What is the function of this protein?
Plays an important role in chromosome cohesion during both mitosis and meiosis (PubMed:12827206).  In prophase of meiosis, it is involved in the formation of the synaptonemal complex (SC) and specifically, in the diplotene and diakinesis phases of prophase, it stabilizes the association of homologous chromosomes during synapsis and sister chromatid cohesion (PubMed:12827206).  It regulates cohesin subunits to promote meiotic chromosome cohesion and localizes non-SMC (structural maintenance of chromosome) cohesin subunits to chromatin prior to or during pre-meiotic S phase (PubMed:12827206).  Implicated in influencing either the stability or loading of meiotic-specific cohesin subunit, rec8 (PubMed:12827206).  Controls cell cycle exit and cell fusion to prevent the premature differentiation into adult cells (PubMed:15691769).  Specifically, regulates hypodermal seam cell identity (PubMed:15691769).
What are the official names of this protein?
Protein timeless homolog.
What is the protein family that this protein belongs to?
Belongs to the timeless family.
What are the subcellular locations of this protein?
Nucleus.
Protein: URE1_PSEE4
Sequence: MSRISRQAYADMFGPTVGDRVRLADTALWVEVEKDFTVYGEEVKFGGGKVIRDGMGQGQMLAAEAMDLVLTNALIIDHWGIVKADIGVKHGRIAAIGKAGNPDVQPGVSVPVGPGTEVIAAEGKIVTAGGIDSHIHFICPQQVEEALTSGVTTFIGGGTGPATGTNATTCTPGPWYLARMLQAADSLPINIGLLGKGNASRPEALREQITAGAVGLKLHEDWGSTPAAIDCCLGVAEEMDIQVAIHTDTLNESGCIEDTLSAIGDRTIHTFHTEGAGGGHAPDIIRAAGQANVLPSSTNPTLPYTVNTVDEHLDMLMVCHHLDPSIAEDVAFAESRIRRETIAAEDILHDMGAFAMTSSDSQAMGRVGEVVLRTWQVAHQMKLRRGPLAPDGSYSDNFRVKRYIAKYTINPALTHGIAHEVGSVEVGKLADLVLWAPAFFAVKPALVLKGGMIATAPMGDINGSIPTPQPVHYRPMFGALGAARHTTRMTFLPQAAMDRGLAEELNLQSLIGVAHGCRRVRKADMVHNTLQPLIEVDAQTYQVRADGELLVCEPARELPLAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSL47_DICDI
Sequence: MTLFSSISSISNPMTSSKSSIASFGSGTSMSSNSNACGGGCGGGNGGILGLGLGLGLNLFGGSRSRGACGGNNGGSGNPGNGPFSGGSCCGSPCCGI
What are the official names of this protein?
HssA/B-like protein 47.
What is the protein family that this protein belongs to?
Belongs to the hssA/B family.
Protein: ARGC_PSEU2
Sequence: MVKVGIVGGTGYTGVELLRLLAQHPQAEVVVITSRSEAGMPVADMYPNLRGHYDGLAFSVPDVKTLGACDVVFFATPHGVAHALAGELLAAGTKVIDLSADFRLQDPVEWAKWYGQPHGAPQLLEDAVYGLPEVNREQIRNARLIAVPGCYPTATQLGFLPLLEAGIADNTRLIADCKSGVSGAGRGLNIGSLYSEANESFKAYAVKGHRHLPEITQGLRRAAGGDIGLTFVPHLVPMIRGIHSTLYATVADRSVDLQALFEKRYADEPFVDVMPAGSHPETRSVRGANVCRIAVHRPQGGDLVVVLSVIDNLVKGASGQAVQNMNILFGLDERAGLSHAGMMP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_STAEQ
Sequence: MAKDTFYITTPIYYPSGNLHIGHAYSTVAGDVIARYKRMQGYDVRYLTGTDEHGQKIQEKAQKAGKTELEYLDEMISGIKNLWSKLEISNDDFIRTTEERHKQVVEKVFERLLKQGDIYLGEYEGWYSVPDETYYTESQLVDPVYENGKIVGGKSPDSGHEVELVKEESYFFNINKYTDRLLEFYDENPDFIQPPSRKNEMINNFIKPGLEDLAVSRTSFDWGVRVPSNPKHVVYVWIDALVNYISSLGYLSDDETLFNKYWPADIHLMAKEIVRFHSIIWPILLMALDLPLPKKVFAHGWILMKDGKMSKSKGNVVDPNVLIDRYGLDATRYYLMRELPFGSDGVFTPEAFVERTNYDLANDLGNLVNRTISMINKYFHGELPAYQGPKHELDEKMEAMALETVKSFNDNMESLQFSVALSTVWKFISRTNKYIDETQPWVLAKDENQREMLGNVMAHLVENIRFATILLQPFLTHAPREIFKQLNINNPDLHQLDSLQQYGMLSEAITVTEKPTPIFPRLDTEAEIAYIKESMQPPKSIKQSDEPGKEQIDIKDFDKVEIKAATIIDAENVKKSEKLLKIKVELDNEQRQIVSGIAKFYRPEDIIGKKVAVVTNLKPAKLMGQKSEGMILSAEKDGVLTLISLPSAIPNGAVIK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADD_MYCPA
Sequence: MTAPLELEQIRKAPKALLHDHLDGGLRPSTVLDIAGQTGYDGLPATDVEELATWFRTRSHSGSLERYLEPFSHTVAVMQTPEALHRVAYECVEDLAEDSVVYAEIRFAPELHINRGMSFDEIVDAVLAGFADGEKACAAAGRPIVVRLLVTAMRHAAVSREIAELAIRWRDKGVVGFDIAGAEAGNPPTRHLEAFDYMRDHNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDIDVLADGPDKGKVRLGRLANILRDKRIPLELCPSSNVQTGAVKSIADHPFDLLARTRFRVTVNTDNRLMSDTYMSREMHRLVQAFGYGWSDLERFTINAMKSAFIPFDERLAIIDEVIKPRYAVLIG
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
What are the official names of this protein?
Adenosine deaminase, Adenosine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
Protein: RUVA_SHIFL
Sequence: MIGRLRGIIIEKQPPLVLIEVGGVGYEVHMPMTCFYELPEAGQEAIVFTHFVVREDAQLLYGFNNKQERTLFKELIKTNGVGPKLALAILSGMSAQQFVNAVEREEVGPLVKLPGIGKKTAERLIVEMKDRFKGLHGDLFTPAADLVLTSPASPATDDAEQEAVAALVALGYKPQEASRMVSKIARPDTSSETLIREALRAAL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: RL16_SHIDS
Sequence: MLQPKRTKFRKMHKGRNRGLAQGTDVSFGSFGLKAVGRGRLTARQIEAARRAMTRAVKRQGKIWIRVFPDKPITEKPLAVRMGKGKGNVEYWVALIQPGKVLYEMDGVPEELAREAFKLAAAKLPIKTTFVTKTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: SRRT_DROVI
Sequence: MADSDDEYDRKRRDKFRGERDSYRPERRDERRPMGGGANSRDEWSERNPFRGSSAAGGGGGGGARHRPDYSDYRGSGPRPRYGSPGREMPPAKRMRPDWGESEMRSNPRFGYDPYLVQAWNDHYQSLHSAYSHSSHPSSARESAPNVVNSDTQTQPAMLTLKQFLDTQDENISDSEVMRKYTEYKTDFKRQQLNEFFVAHKDEEWFKNKYHPEDSVRRSEEQRGFLKRRTDVFLELLENGTIGSVKVDSSQADSLVRVLDTCVIKLEGGTDEDLKILDEKPKETPVVYERKSESTEASVVAKREPESPKQTKSEKGADEEQPVVVSPQRKSLRPVNSDEENWDDENDEMAAPAKVQGDDDSIKSGSDKKLKKKKIKKRNRNSSDDESSSSSSFESDSDSDDEKLKAKYDVEEGLRADQKAEAQKDKEEAATVAKANPLPPDSPQPEGGTALQDAAAIKSEQSDEQQEKDAEQPAELQADEPAAAKNGEEPEKTEKNEVETKSTADDVTETIDLDKVKDGPQPRALHRTSSIFLRNLAPSITKAEIEAICTRFSGYLRVAIADPLVERRWYRRGWITFTRDVNIKEICWSLNNQRLRDCEMGAIVNRDLSRRVRPANGITAHKQIVRADIKLCAKIAMNLDERFKLWSEADSTQQQPDAESKPSADATNGSGGSSTTYGFNSKNPVLQNITDYLIEEASAEEEELLGLAGDNKDGEGEPIERDEQLISVLDRLVLYLRIVHSVDYYNHCEYPYEDEMPNRCGIIHARGPPPMRVTSNDVQEYIKAYDGKLQQFLTKSVQLSDDEIKELGAKNPETEVEKFVQANTQELAKDKWLCPLSGKKFKGPEFIRKHIFNKHEEKVDEVRKEVQYFNNYLRDPKRPQLPEHPGSSKRTESESGRGSGGYRPPMYPPFSAMPYGFAPPMMGGGGRGGRNFPPVRREMPLEHQRRLIGYHDLDAPVNSDMFD
What is the function of this protein?
Acts as a mediator between the cap-binding complex (CBC) and RNA-mediated gene silencing (RNAi).  Involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production.  Also involved microRNA (miRNA)-mediated silencing by contributing to the stability and delivery of primary miRNA transcripts to the primary miRNA processing complex containing drosha and pasha (By similarity).
What are the official names of this protein?
Serrate RNA effector molecule homolog, Arsenite-resistance protein 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the ARS2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: IOLA_LISMH
Sequence: MADVRKLKNYIDGEWVESKTDKYEDVINPATGEVLCQVPISTRAELDQAAVIAEQAFEKWSQVAVPRRARVLFSFQQLLIQHKEELARLITLENGKNLSEARGEVQRGIENVEFAAGAPTLMMGDSLASIATDVEAANYRYPVGVVGGIAPFNFPMMVPCWMFPMAIALGNSFILKPSERTPLLMEKLVELFSEAGLPKGVFNVVYGAHDVVNGILENEIIKAVSFVGSKPVGEYVYKTGSANLKRVQALTGAKNHTIVLNDADLEDTVTNVISAAFGSAGERCMACAVVTVEEDIADEFLEALRTAAKNVKIGNGLDDGVFLGPVIREENQKRTIAYIEKGVEEGAKLTVDGRETGLSEGHFVGPTILEDVTTDMTIWKDEIFAPVLSVIRVKNLQEAVRVANLSEFANGACIFTNNAKAIRYFREKIDAGMLGVNLGVPAPMAFFPFSGWKSSFYGTLHANGKDSVDFYTHKKVVTARYSLKGYEE
What is the function of this protein?
Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively.
What are the official names of this protein?
Malonate-semialdehyde dehydrogenase, MSA dehydrogenase, Methylmalonate-semialdehyde dehydrogenase, MMSA dehydrogenase, MSDH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. IolA subfamily.
Protein: PG114_VACCC
Sequence: MSINIDIKKITDLLNSSILFPDDVQELLREKYIVLERKSNGTPTVAHIYKTMARFDNKSIYRIAKFLFMNRPDVIKLLFLEDVEPLLPDKSINISINNTEYPQLEGPIGTKIALLELFNAFRTGISEPIPYYYLPLRKDINNIVTK
What is the function of this protein?
Late protein which is part of a large complex required for early virion morphogenesis.  This complex participates in the formation of virosomes and the incorporation of virosomal contents into nascent immature virions.
What are the official names of this protein?
Core protein D2.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG114 family.
Protein: NUOK2_AQUAE
Sequence: MKTIPLEAFLTVSMILFGLGLIGIIARRNLVTVLMSLELALNAVNIALVGADHYLGLAEGQIFALFIIALAATEAAVGLGIIIAIFRLKKVESTDEIRELRG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K 2, NADH dehydrogenase I subunit K 2, NDH-1 subunit K 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.