PharMolix/UniProtQA huggingface dataset:
Protein: VL2_HPV10
Sequence: MVAQRARRRKRASATQLYRTCKASGTCPPDVIPKVEGTTLADRILQWGSLGVYLGGLGIGTGSGTGGRTGYVPISTRPGTVVDVSVPARPPVVIEPVGPSDPSIVNLLEDSSIINSGSTIPTFSGTSGFEVTSSATTTPAVLDITPASENVVISSTNFTNPAFTEPSLVEVPQSGEVSGHILISTPTAGTHGYEEIPMDTFASSGTGTEPISSTPVPGVSRIAGPRLYSRANTQVKVSDPAFLSRPSSLLTFDNPVFEPEDETIIFERPYSPSRVPDPDFLDIVRLHRPALTSRRGTVRFSRLGQKFSMRTRSGKGIGARVHYYQDLSPIAPIEDIEMEPLLAPAASDTIYDIFADVDDGDVAFTEGYRSTTQSRGYNTTSPLSSTLSTKYGNVTIPFVSPVDVTLHTGPDIVLPTSAQWPYVPLSPADTTHYVYIDGGDFYLWPVTFHFSRHRRRKRVSYFFADGTLAL
What is the function of this protein?
Minor protein of the capsid that localizes along the inner surface of the virion, within the central cavities beneath the L1 pentamers.  Plays a role in capsid stabilization through interaction with the major capsid protein L1.  Once the virion enters the host cell, L2 escorts the genomic DNA into the nucleus by promoting escape from the endosomal compartments and traffic through the host Golgi network.  Mechanistically, the C-terminus of L2 possesses a cell-penetrating peptide that protudes from the host endosome, interacts with host cytoplasmic retromer cargo and thereby mediates the capsid delivery to the host trans-Golgi network.  Plays a role through its interaction with host dynein in the intracellular microtubule-dependent transport of viral capsid toward the nucleus.  Mediates the viral genome import into the nucleus through binding to host importins.  Once within the nucleus, L2 localizes viral genomes to host PML bodies in order to activate early gene expression for establishment of infection.  Later on, promotes late gene expression by interacting with the viral E2 protein and by inhibiting its transcriptional activation functions.  During virion assembly, encapsidates the genome by direct interaction with the viral DNA.
What are the official names of this protein?
Minor capsid protein L2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L2 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host early endosome. Host Golgi apparatus.
Protein: HIS4_ACIBT
Sequence: MLIIPAIDLKDGKCVRLKQGRMEDDTVFSDDPVATAQHWVNEGARRLHLVDLNGAFAGTPIHKPVVEAIAKAQPELPIQIGGGIRSLETIEHYLEAGVTFVIIGTKAVQEPEFVEEACKRFAGHIIVGIDAMNGMVATDGWANVTDVKATDLAKRFADAGVSSIVYTDIARDGMMQGVNVEQTVNLAQYSGLPVIASGGVTNLDDVRNLKGQPGILGAITGRAIYEGTLNLREAQLLLDENRL
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHED_CLOBJ
Sequence: MDIKEIKVGIADLNVGKNPDKIITVGLGSCIGIALYDGIKCIGGLSHIMLPDSTQFSKVTNPMKFADLAIPILVEKMEKLGARKNGLKAKICGGASMFNFSDKSMVMDIGNRNGKAVKEKLKELSIPLLAEDIGGNKGRTMIFDTSTGKVYIKTVGLGTKEI
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: Y7146_DICDI
Sequence: MMNFATRSVLRGSIKVNRLYTASASSSSSTRIPSGFASATSSKSNSSTKSSPSPINSFNNKTNNIFKSNATNNSSLAFGIVEFMVFNGMISTITTTTFNNNNNNNNK
What are the official names of this protein?
Putative uncharacterized protein DDB_G0286831.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SPEE_ARCFU
Sequence: MVWFFEYYDGCGLAIKVKKKLYEAEGVQKVEIYETESMGKMLVIDGKIQLTELDEPFYHEMLVHVPMLSHENPRKVAVIGGGDGGALREVLKHNVERAVLVDIDRNVIDLSRKFLKIDHGAFEDERVEIAIMDGKEFLRDCEIFDVIIVDSTDPVGVSDTLFDREFFELARQKCDVISLQSQSPLIQKEYFRTLLVNSAPFERRDVYLSCVPTYPLALWSFIIGGEYDFSNLEERFERIKGKTVHYNPDVHRAAFALPEWLKKEVEACI
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNG_STRP2
Sequence: MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKKSHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWGAYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANTFLKETGQEPIDWLR
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y922_METBU
Sequence: MLGASEPEDVIKQCTQVLEHIANDNSVPRNIRRSANDILATLKNEAEPLFLRTSSSISILEDISNDPNIPLHTRTLIWNVASQLETIPVDE
What are the official names of this protein?
UPF0147 protein Mbur_0922.
What is the protein family that this protein belongs to?
Belongs to the UPF0147 family.
Protein: KRFB_MYCAM
Sequence: MSCYDLCRPCGPTPLANSCNEPCVRQCQDSRVIIEPSPVVVTLPGPILSSFPQNTAVGSTTSAAVGSILSAEGVPISSGGFSLSGLGGRYSGRRCLPC
What are the official names of this protein?
Feather beta keratin, F-ker.
What is the protein family that this protein belongs to?
Belongs to the avian keratin family.
Protein: S22AF_XENTR
Sequence: MEVEGALKLVGEMGIYQIYLSFLLAVLLQLYSATEAIIITILGATPPYHWMNDSLTANGSRGKQYGSQLPAEGEHGHVVFDGNFTSIVSEWFLVGGAAYEVSVSSSVYFGGVLIGVISFGQLSDRFGRKPVYVTGLALEVVFAVMNALTPIFPLFLLTRFLVGVMNGGMSLVAFVLLNECIGASYWAAAGSLGSLCFAVGIAQFALIGYFIRSWRLLALLVNVQGAAVLALSLCIPESPRWLHAQGRLREAQESLLSLGRRNRRKVTSFTLCPRQKDSAHSANILTIYSNAILRQRTLIMMWVWFVCSLVYYGLTLSSGDLGGDIYLNLALSGLAELPAYPLCMYLINHKRVGRRGSLAGFLCVGGGACLLIMLVPGKTGSGPLSVLNSQTLSLLGKLNISAAFNIVYIYSSELYPTCVRNLGMGVCSMFSRIGGIIAPFIPALRFAHWALPFIVFGAAGVSAGLLSLLLPETLSAPLPETLADLRGAPYRRLEPDGEAMLHRPQAELGAFTNGSSEEDEEEELDAVRECQALI
What is the function of this protein?
Probably transports organic cations.
What are the official names of this protein?
Solute carrier family 22 member 15.
What is the protein family that this protein belongs to?
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SL6_DABSI
Sequence: MGRFISVSFGLLVVFLSLSGTGADCPSEWSSHEGHCYKVFKLLKTWEDAEKFCTEQKKGSHLVSLHSREEEKFVVNLISENLEYPATWIGLGNMWKDCRMEWSDRGNVKYKALAEESYCLIMITHEKVWKSMTCNFIAPVVCKF
What is the function of this protein?
Interferes with one step of hemostasis (modulation of platelet aggregation, or coagulation cascade, for example).
What are the official names of this protein?
Snaclec 6, C-type lectin-like 6.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: DPOL_HHV1K
Sequence: MFSGGGGPLSPGGKSAARAASGFFAPAGPRGAGRGPPPCLRQNFYNPYLAPVGTQQKPTGPTQRHTYYSECDEFRFIAPRVLDEDAPPEKRAGVHDGHLKRAPKVYCGGDERDVLRVGSGGFWPRRSRLWGGVDHAPAGFNPTVTVFHVYDILENVEHAYGMRAAQFHARFMDAITPTGTVITLLGLTPEGHRVAVHVYGTRQYFYMNKEEVDRHLQCRAPRDLCERMAAALRESPGASFRGISADHFEAEVVERTDVYYYETRPALFYRVYVRSGRVLSYLCDNFCPAIKKYEGGVDATTRFILDNPGFVTFGWYRLKPGRNNTLAQPRAPMAFGTSSDVEFNCTADNLAIEGGMSDLPAYKLMCFDIECKAGGEDELAFPVAGHPEDLVIQISCLLYDLSTTALEHVLLFSLGSCDLPESHLNELAARGLPTPVVLEFDSEFEMLLAFMTLVKQYGPEFVTGYNIINFDWPFLLAKLTDIYKVPLDGYGRMNGRGVFRVWDIGQSHFQKRSKIKVNGMVNIDMYGIITDKIKLSSYKLNAVAEAVLKDKKKDLSYRDIPAYYATGPAQRGVIGEYCIQDSLLVGQLFFKFLPHLELSAVARLAGINITRTIYDGQQIRVFTCLLRLADQKGFILPDTQGRFRGAGGEAPKRPAAAREDEERPEEEGEDEDEREEGGGEREPEGARETAGRHVGYQGAKVLDPTSGFHVNPVVVFDFASLYPSIIQAHNLCFSTLSLRADAVAHLEAGKDYLEIEVGGRRLFFVKAHVRESLLSILLRDWLAMRKQIRSRIPQSSPEEAVLLDKQQAAIKVVCNSVYGFTGVQHGLLPCLHVAATVTTIGREMLLATREYVHARWAAFEQLLADFPEAADMRAPGPYSMRIIYGDTDSIFVLCRGLTAAGLTAMGDKMASHISRALFLPPIKLECEKTFTKLLLIAKKKYIGVIYGGKMLIKGVDLVRKNNCAFINRTSRALVDLLFYDDTVSGAAAALAERPAEEWLARPLPEGLQAFGAVLVDAHRRITDPERDIQDFVLTAELSRHPRAYTNKRLAHLTVYYKLMARRAQVPSIKDRIPYVIVAQTREVEETVARLAALRELDAAAPGDEPAPPAALPSPAKRPRETPSHADPPGGASKPRKLLVSELAEDPAYAIAHGVALNTDYYFSHLLGAACVTFKALFGNNAKITESLLKRFIPEVWHPPDDVAARLRAAGFGAVGAGATAEETRRMLHRAFDTLA
What is the function of this protein?
Replicates viral genomic DNA.  The replication complex is composed of six viral proteins: the DNA polymerase, processivity factor, primase, primase-associated factor, helicase, and ssDNA-binding protein.  Additionally, the polymerase contains an intrinsic ribonuclease H (RNase H) activity that specifically degrades RNA/DNA heteroduplexes or duplex DNA substrates in the 5' to 3' direction.  Therefore, it can catalyze the excision of the RNA primers that initiate the synthesis of Okazaki fragments at a replication fork during viral DNA replication (By similarity).
What are the official names of this protein?
DNA polymerase catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Host nucleus. Note=The protein is present at discrete sites in nuclei, called replication compartments where viral DNA replication occurs.
Protein: URE1_RHOPA
Sequence: MSTRISRSVYADMFGPTTGDRVRLADTDLIIEVEKDLTTYGEEVKFGGGKVIRDGMGQSQVTNKDGAADTVITNALIVDHWGIVKADVAITAGVITAIGKAGNPDVQPNVDIIIGPGTDVIAGEGKILTAGGFDSHIHFICPQQIEHALMSGVTTMLGGGTGPSHGTFATTCTPGPWHIGRMIQSFDAFPVNLGISGKGNAALPGPLKEMIEGGACALKLHEDWGTTPAAIDNCLTVADAYDIQVMIHTDTLNESGFVEDTVKAFKGRTIHAFHTEGAGGGHAPDIIKVASLENVLPSSTNPTRPFTRNTIDEHLDMLMVCHHLDPSIAEDLAFAESRIRKETIAAEDILHDLGALSMMSSDSQAMGRLGEVIIRTWQTADKMKKQRGALPQDSARNDNFRVKRYIAKYTINPAIAHGVSKLIGSVETGKMADLVLWSPAFFGVKPDCIIKGGSIVAAPMGDPNASIPTPQPVHYQPMFGAYGKALTASSVVFTSQAAAAGNLARDLGIAKKLVPVSNVRGGISKKSMIHNDATPKLEVDPETYEVRADGELLTCAPAEVLPLAQRYFMF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREG_MAGMM
Sequence: MSNPLRVGVGGPVGSGKTALLEWLCREMQQHYSVAAITNDIYTKEDQRILTASGALPAERIMGVETGGCPHTAIREDASMNLAAVEDMQLRFADLELIFIESGGDNLAATFSPELADLTLYVIDVAAGEKIPRKGGPGITRSDLLVINKTDLAPLVGADLAVMEQDTLRMRGSRPFVFTNLKQGDGVAAIIQFLVEKGGLGV
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSTX_BACSU
Sequence: MFCTFFEKHHRKWDILLEKSTGVMEAMKVTSEEKEQLSTAIDRMNEGLDAFIQLYNESEIDEPLIQLDDDTAELMKQARDMYGQEKLNEKLNTIIKQILSISVSEEGEKE
What is the function of this protein?
Chaperone that facilitates the production and integration of integral membrane proteins into the bacterial lipid bilayer.
What are the official names of this protein?
Protein mistic, Membrane-integrating protein MstX.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Folds autonomously into the membrane, bypassing the cellular translocon machinery.
Protein: HSL42_DICDI
Sequence: MTLFSSISSMSTSMSGSKSSISSFGSGTSMGSNSIACGGCGGSGGILGSGLGLGLGLGLDLTGGSRSRGACGGNRGNGNGNGGMGGGNGSCCGGPCCGI
What are the official names of this protein?
HssA/B-like protein 42.
What is the protein family that this protein belongs to?
Belongs to the hssA/B family.
Protein: DAPA_DINSH
Sequence: MFKGSMPALVTPMKDGAVDFATLEALVEWQIAEGSHGLVPVGTTGESPTLSHEEHEAVVAKVIEVAAGRVPVIAGAGSNNTVEAVRFVRHAKDAGADGALVVTPYYNKPTQGGMIAHYTALAEAADIPIVIYNIPGRSVVDMTPATMAALAALPTIVGVKDATGDLARVSQTRMACGPEFIQLSGEDATALGFNAHGGVGCISVTANVAPALCAQFQEATLAGDFATALALQDKLMPLHEAIFVEPGLVGAKYALSLLGKCSEDVRLPLLGLSDGTKVLIKDAMIHAGILG
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLOT3_MEDTR
Sequence: MYRVAKASEYLAITGAGIDDIKLQKKAWIFPGQSCTVFDLSPVNYTFEVQAMSAEKLPFVLPAVFTIGPRVDDQESLLKYAKLISPHDRHSNHVNELVQGIIEGETRVLAASMTMEEVFRGTKQFKQEVFDKVQLELNQFGLLIYNANVKQLVDVPGHEYFSYLGQKTQMEAANQAKVDVAEAKMKGEIGSKLRVGQTLQNAAKIDAETKVIAMQRAGESEKQGIKVRTEVKVFENQREAEVAEANSELAKKKAAWTKAAQVAEVEAKKAVALREAELQGEVEKMNALTTTEKLKADLLSKASVQYETKVQEANWELYKKQKEAEAILFEKKAEAEAQKALADSTFYARKQEAEAELYAKKKEAEGIVTLGNAQGAYVSTLLNALGNNYTAVRDYLMINGGMFQEIAKINAEAVRGLEPKISIWTNGGDNSGGEGAMKEVAGVYKMLPPLFKTVHEQTGMLPPAWMGSLSDKSS
What is the function of this protein?
May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles (By similarity).  May be involved in nodule formation.
What are the official names of this protein?
Flotillin-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the band 7/mec-2 family. Flotillin subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Membrane, caveola.
Protein: HEMH_HYPNA
Sequence: MGRRIAVVLFNLGGPDTGNDVQPFLKNLFRDPAIIRAPLPVRWLVARLISTLRAPVVKQNYAMMDAGGGSPLLRETKKQADALQAELAKKLPGDEVRCFIAMRYWHPFTEEAAAEVQKWGADEVVLLPLYPQFSTTTTGSSLSAWHKAYKGKSRTICCYPFEENFVSAHVDQIMAAWERAGRPGNVNLLLSAHGLPESVVKSGDPYQWQCEALAEMIAGRVPADWEVSVCYQSRVGPMKWIGPPTEEEIARISDQGRNILIAPIAFVSEHIETLVELGEEYRLVAEKHGAASYTRVEALGVHPGFISTLTGEVLAALGMKETIRSCAGGRLCPSGWSGCPQAELKQKAGVRITETAG
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRIS_METJA
Sequence: MNTFAEVQKLYREYYNFAIKNNILEIPEGIEYREFGYGYLKKVDNRNLSFKNEREYKDWVLKNAPMHFYKSLAYMLYPNKSGGASKKGIFRRELAFDIDVHKTKKCKHEDDWICKHCLEEAKNQAIYLIEEFLIPDFGLNEEDLKIVFSGNRGYHIYIKPRDEKIRDIIESYSKEDRRFLMDYILGKNLNLNSVGSGWRRRLIKAIKERDKRISTKKLENEKNWKKVIENLKSKNKIYNIIEETKNKIELDEKVMDDDIRLLRVINSLHGYTGFIVKPLSGLDELRRFNPLEDAIFKDFENKVYEVNIFDDRKFEIEICGKKYNNKSKKITASALLYLFGHNIKFELLKS
What is the function of this protein?
Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.  The small subunit contains the primase catalytic core and has DNA synthesis activity on its own.  Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability.  The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis.  May also play a role in DNA repair.
What are the official names of this protein?
DNA primase small subunit PriS.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic-type primase small subunit family.
Protein: RAF_YEAST
Sequence: MPYKTAIDCIEELATQCFLSKLTDDDVSTFRRVCSKENDIIKLALRIPRTIDYTSILRLLYDTLPLRSLSFNEALPLFCYSIDPAQQRQCDLRFYLRDVVKLARPRKRLEMQKALLQWLPSLLSDVTLQLLNDIRIRFEEIQPNIRQTVLQIYDRTCYPSLNFEHPNLGVFPETDSIFEPV
What is the function of this protein?
Plays a role in 2-micron plasmid partitioning.  Antagonizes transcriptional repression of recombinase FLP by REP1-REP2 (PubMed:2832156).  Regulates both stability and copy number of the plasmid by blocking the formation of the REP1-REP2 repressor complex (PubMed:28472368).
What are the official names of this protein?
Trans-acting factor D, REP-antagonizing factor, Recombinase-activating factor, RAF.
Protein: PYRG_VIBCH
Sequence: MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLKVTMMKLDPYINVDPGTMSPTQHGEVFVTEDGAETDLDLGHYERFIRTKMTKRNNFTAGRVYADVLRKERRGDYLGATIQVIPHITNAIKDRVIAGSEGHDIAIVEVGGTVGDIESLPFMEAIRQLAIEVGREHAMFMHLTLVPYLAAAGEVKTKPTQHSVKELLSIGIQPDILVCRSDRMIPANERKKIALFCNVPEKAVISMKDVDSIYKIPQLIRSQGLDDLVCARFGINAPEADLSEWEQVIYEEANPTGEVTIGMVGKYTELPDAYKSVNEALKHAGLKNRLSVTIKYVDSQDVETKGTDVLNGLDAILVPGGFGDRGIEGKIRAAQYARENKIPYLGICLGMQVALIEYARNVAGMEGAHSTEFNKNTKYPVVGLITEWVDGEGNVEERSEKSDLGGTMRLGSQLCHLEKGTKAYELYGSATIHERHRHRYEVNNLLRPQIEKAGLKVSGLSADKKLVEVIENPAHPWFVAAQFHPEFTSTPRDGHPLFAGFVKAAGQFQRGELK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: RUVB_PSEFS
Sequence: MIEADRLIAATGPRDREEVQDRAIRPLSLADYIGQPTVREQMELFIQAARGRSESLDHTLIFGPPGLGKTTLANIIAQEMGVSIKSTSGPVLERPGDLAALLTNLEPHDVLFIDEIHRLSPIVEEVLYPAMEDFQLDIMIGEGPAARSIKLDLPPFTLVGATTRAGMLTNPLRDRFGIVQRLEFYSTADLATIVSRSAGILGLPLDPEGAFEIARRARGTPRIANRLLRRVRDFAEVRAKGHITKAVADLALNLLDVDEHGFDHQDRRLLLTMIEKFDGGPVGVDSLAAAISEERHTIEDVLEPYLIQQGYIMRTPRGRVVTRHAYLHFGLNIPSRLGEMPVVDEFLDAVDD
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: A70A_DROME
Sequence: MKTLALFLVLVCVLGLVQSWEWPWNRKPTKFPIPSPNPRDKWCRLNLGPAWGGRC
What is the function of this protein?
Male seminal protein which triggers short- and long-term post-mating behavioral responses (PMR) in female Drosophila (PubMed:3135120, PubMed:19249273, PubMed:20308537, PubMed:19793753, PubMed:15694303, PubMed:24089336).  Binds initially to sperm where it is later cleaved to release an active peptide within the female reproductive tract.  Signals via the sex peptide receptor (SPR) in female flies; may also act via other receptors (PubMed:20458515, PubMed:20308537, PubMed:24089336).  Moderates the activity of distinct neuronal circuitries in the female genital tract to promote specific PMRs including: enhanced ovulation, increased egg laying rate, increased feeding/foraging rate, induced antimicrobial peptide synthesis, reduced mating receptivity, reduced day-time sleep and reduced lifespan in multiple mated females (PubMed:3135120, PubMed:15694303, PubMed:19249273, PubMed:19793753, PubMed:24089336).
What are the official names of this protein?
Accessory gland-specific peptide 70A, Paragonial peptide B, Sex peptide, SP.
What is the protein family that this protein belongs to?
Belongs to the Drosophila sex peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: SUCC_PARUW
Sequence: MNTHEFQAKQILRKYGIPVPDFYIASSSKEVEEIIKQYQLQSAIIKVQVHAGGRGKAGGVKLATNPQEILEFSQELIGKKIINEQTGPSGMISHQVLISPAILIKKEFYLGITINRELASRVLIASPIGGVNIEKIAHEQPNQLLMLPIPLEETFRSYHLIRIASFMGWKGKQIQEGVAIIQSLVKAFKETDASLLEINPLVETKEGHLLALDAKLSIDDNALFKHEDLKTLFDPSQMSNNEARAQQFELAYVALEGEIGCMVNGAGLAMATMDLIQYHGGRPANFLDVGGGASQVKVAEGFRIILSDSNVKAILINIFGGIMNCETLASGIIEAAKGLQIHIPLIVRMEGTNVEKGKQLLQQSGLKILITENLTEAAQQAVQLAQSVR
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: RSMH_SALPA
Sequence: MMENFKHTTVLLDEAVNGLNIRPDGIYIDGTFGRGGHSRLILSQLGEEGRLLAIDRDPQAIAVAQAISDPRFSIIHGPFSALADYVAERELTGKIDGILLDLGVSSPQLDDAERGFSFMRDGPLDMRMDPTRGQSAAEWLQTAEEADIAWVLKTFGEERFAKRIARAIVERNREQPMTRTKELAEVVAAATPVKDKFKHPATRTFQAVRIWVNSELEEIEQALKSSLSVLAPGGRLSIISFHSLEDRIVKRFMREQSRGPQVPAGLPMTEAQLKKLGGRELRALGKLMPGEKEVAENPRARSSVLRIAERTNA
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COXX_SALTO
Sequence: MSMITERPVSDPAGQSVSATGDGAVGSRRDMRAVVAAYVALTKPRIVELLLVTTVPAMMLAHGGLPSLWLMAVVLVGGSLAAGAASVLNCYIDRDIDQVMRRTKRRPLPAHTVAPRNALIFGLVLATVSVTLLAVFTNALAAGLTLAAILYYDLVYTAWLKRTTTANTFWGGACGAAPVLIGWAAVTGSLAPAAWALFGVVFFWQMPHFYPLAMKYKDDYARAGIPMLPVVASTRRVNAEILVFAWLTVLVSLVTWPLGAGMGPIYGLPTLVVGVIFLVEAHRLCRRAARGEAVKPMRLFHWSTTYLTVVFAAVALDALI
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HIS1_HALLT
Sequence: MRIAVPNKGRLHDPTLSLLERAGLHTEETADRQLYADTVDPDVSILFARAADIPEYVRDGAADVGITGLDQAAESGGVADSASAAGDDDLVDLLDLGYGSCKLVLAAPEDGDISVVADLAGGTVATEFPNITRDYLDRVDVDADVVTVTGATELTPHVDMADAIVDITSTGTTLKVNRLAVIDDVLDSSVRLFARPDMVDDAKVKQVLTAFESVLAADGRRYLMMNAPKERLDEVKDVIPGLGGPTVMDVEADENGNGMVAVHAVVEERDVFATISELKSVGATGILVTKIERLVG
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.