PharMolix/UniProtQA huggingface dataset:
Protein: KLH35_HUMAN
Sequence: MRQGHAPEESEPGCEAPCAGPCHAQRVLQALNAYRRSGTLTDVVLRAGGRDFPCHRAALSAGSAYFRSLFAAGRPERGPAVVPVVPVAPEAPGTSPAGAAAALAVVLDYVYGAGVRLRAEDEAAAVLALAERLGVAGLREACVRFLEGRLRAANSLALRRVAAAFSLAPLAERCGRVLRQAFAEVARHADFLELAPDEVVALLADPALGVAREEAVFEAAMRWVRHDAPARRGQLRRLLEHVRLPLLAPAYFLEKVEADELLQACGECRPLLLEARACFILGREAGALRTRPRRFMDLAEVIVVIGGCDRKGLLKLPFADAYHPESQRWTPLPSLPGYTRSEFAACALRNDVYVSGGHINSHDVWMFSSHLHTWIKVASLHKGRWRHKMAVVQGQLFAVGGFDGLRRLHSVERYDPFSNTWAAAAPLPEAVSSAAVASCAGKLFVIGGARQGGVNTDKVQCFDPKEDRWSLRSPAPFSQRCLEAVSLEDTIYVMGGLMSKIFTYDPGTDVWGEAAVLPSPVESCGVTVCDGKVHILGGRDDRGESTDKVFTFDPSSGQVEVQPSLQRCTSSHGCVTIIQSLGR
What are the official names of this protein?
Kelch-like protein 35.
Protein: MURE_XANAC
Sequence: MSRSMALSQLLPDVALTHDVQVSGLVMDSRAVRPGDAFVAIAGFGAHGLGFVEQARANGAAAVLFEPPAPDGLPVPADAIAVPGLRARLGVMADQFHGRPSQAMRMVGVTGTNGKTSTVQLLAQALTLLGTPTGTLGTLGVGLYGAAVPTGFTTPLVLPTHALLAQLRDDGAQAVAMEVSSHALDQGRVDAVHFDVAVFTNLTRDHLDYHGDMAQYGAAKAKLFARAGLKAAVVNLDDAFGHTLFAALDPALRAIGVSSRAHADASVSAQALQLDHNGINFALNIRGQVHPVHSPLLGRFNVDNLLAVAGALWAMEFAPAQIASVLGQLQPIHGRMNRLGGAHGAPLVVVDYAHTPDALEQALSSLRSHAQDRLICVFGCGGERDTGKRPQMAAIAELKADVAIVTDDNPRGEDGDAIVADILRGFARPDAAIVQRDRAAAIHQAIGMASPSDIVLIAGKGHEPYQEVAGVRHAFDDALVAAQALLPRTVLGVRP
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y104_MYCVP
Sequence: MSSLRTDNDTWDIASSVGATAVMVAAARAAETERPEPLIDDPYAKILVAGAGNGAWQYIADDGFVAKVTESDPEIGPLFEHMKNYQAVRTHFFDAFFAAAVDAGIRQIVILASGLDSRAFRLPWPAGTTVFEIDQPLVLAYKSSTLASHGVQPTADRREVPIDLRQDWPTALTHAGFDADQPTAWLAEGLLMYLPADAQDRLFAQITELSAPGSRVAAESMGIHAQDRRERMRERFASITAQFDVEPMDITELTYEDPDRADVAQWLTAHGWRAEAVPSQDEMRRLHRLVEIADGDDQSFSTFTTAVKR
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase Mvan_0104.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: NRCAM_CHICK
Sequence: MMKEKSISASKASLVFFLCQMISALDVPLDSKLLEELSQPPTITQQSPKDYIVDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDAQVTMKPNSGTLVVNIMNGVKAEAYEGVYQCTARNERGAAISNNIVIRPSRSPLWTKEKLEPNHVREGDSLVLNCRPPVGLPPPIIFWMDNAFQRLPQSERVSQGLNGDLYFSNVQPEDTRVDYICYARFNHTQTIQQKQPISVKVFSTKPVTERPPVLLTPMGSTSNKVELRGNVLLLECIAAGLPTPVIRWIKEGGELPANRTFFENFKKTLKIIDVSEADSGNYKCTARNTLGSTHHVISVTVKAAPYWITAPRNLVLSPGEDGTLICRANGNPKPSISWLTNGVPIAIAPEDPSRKVDGDTIIFSAVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANKLYQVIADSPALIDCAYFGSPKPEIEWFRGVKGSILRGNEYVFHDNGTLEIPVAQKDSTGTYTCVARNKLGKTQNEVQLEVKDPTMIIKQPQYKVIQRSAQASFECVIKHDPTLIPTVIWLKDNNELPDDERFLVGKDNLTIMNVTDKDDGTYTCIVNTTLDSVSASAVLTVVAAPPTPAIIYARPNPPLDLELTGQLERSIELSWVPGEENNSPITNFVIEYEDGLHEPGVWHYQTEVPGSHTTVQLKLSPYVNYSFRVIAVNEIGRSQPSEPSEQYLTKSANPDENPSNVQGIGSEPDNLVITWESLKGFQSNGPGLQYKVSWRQKDVDDEWTSVVVANVSKYIVSGTPTFVPYEIKVQALNDLGYAPEPSEVIGHSGEDLPMVAPGNVQVHVINSTLAKVHWDPVPLKSVRGHLQGYKVYYWKVQSLSRRSKRHVEKKILTFRGNKTFGMLPGLEPYSSYKLNVRVVNGKGEGPASPDKVFKTPEGVPSPPSFLKITNPTLDSLTLEWGSPTHPNGVLTSYILKFQPINNTHELGPLVEIRIPANESSLILKNLNYSTRYKFYFNAQTSVGSGSQITEEAVTIMDEAGILRPAVGAGKVQPLYPRIRNVTTAAAETYANISWEYEGPDHANFYVEYGVAGSKEDWKKEIVNGSRSFFVLKGLTPGTAYKVRVGAEGLSGFRSSEDLFETGPAMASRQVDIATQGWFIGLMCAVALLILILLIVCFIRRNKGGKYPVKEKEDAHADPEIQPMKEDDGTFGEYRSLESDAEDHKPLKKGSRTPSDRTVKKEDSDDSLVDYGEGVNGQFNEDGSFIGQYSGKKEKEPAEGNESSEAPSPVNAMNSFV
What is the function of this protein?
This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.  Specifically involved in the development of optic fibres in the retina.
What are the official names of this protein?
Neuronal cell adhesion molecule, Nr-CAM, Neuronal surface protein Bravo, gBravo, NgCAM-related cell adhesion molecule, Ng-CAM-related.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: Y317_STACT
Sequence: MGRKWNNIKEKKAQKDKNTSRIYAKFGKEIYVAAKSGEPDPESNQNLRLVLERAKTYNVPRNIIDRAIDKAKGSDDENYDNLRYEGFGPNGSMLIVDALTNNVNRTASDVRAAFGKNGGNMGVSGSVSYMFDHTATFAFEGKSADEILEVLMEQDLDVRDVVDDGNLTIVYAEPDQFAQVQDALRQDGVEDFQVAEFEMLPQNDIQLSDEDKATLEGLIDALEDLEDVQNVYHNVDLDS
What are the official names of this protein?
Probable transcriptional regulatory protein Sca_0317.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family. YeeN subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MENG_CHLPN
Sequence: MEPSTNKPDCKKIFDSIASKYDRTNTILSLGMHHFWNRSLIQILGSGYSLLDLCAGTGKVAKRYIAAHPQASVTLVDFSSAMLDIAKQHLPQGSCSFIHSDINQLPLENHSYPLAAMAYGLRNLSDPHKALQEISRVLMPSGKLGILELTPPKKTHPTYSAHKLYLRAVVPWIGKSVSKDPDAYSYLSKSIQQLPKDHDLEDLFSKSGFYIAKKKKLFLGAATIWLLEKQ
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
What are the official names of this protein?
Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: PANB_PROM0
Sequence: MLPSDLVNYKKKSRKIIALTAWDSISGSIAEQANVDLVLVGDSLAMVCLGYQSTLPITLENIIYHTNAVSRGFKKKIEEQPLVVSDMPFMTYQCGEDKAVEYAGKIIQSTYAKAVKVEGAEPEIQKVISRLIRMGIPVMGHIGLTPQSYLNIGLRKQGESLASQEKIKKEASILEELGCFSIVLEHIPDLLAKEIQNSLTIPTIGIGAGNYCDGQVRVTADLLGLNDDQPPFCQPIIQGKKLFKDKLKEWVDSERLS
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y658_COXBU
Sequence: MSAILPTEADRRLLSDIKESITDMQQQMQATYSNLADLKLVGESHDKTVRITMTATYNFEDIEFDERALQGGVKEFKWRIREAWKNLCETIQKTTQSKTIELLQSMRIPEDIRNLSVEEEGGEGGEGGQGTRGMIGNPIASGG
What are the official names of this protein?
Uncharacterized protein CBU_0658.
Protein: HBEAG_HBVGB
Sequence: MQLFHLCLIISCSCPTVQASKLCLGWLLGMDIDPYKEFGASVELLSFLPSDFFPSVRDLLDTASALYREALESPEHCSPNHTALRQAVLCWGELMTGCSWVGNNLEDPASRELVVNYVNTNMGLKIRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRGRSPRRRTPSPRRRRSQSPRRRRSQSPASQC
What is the function of this protein?
May regulate immune response to the intracellular capsid in acting as a T-cell tolerogen, by having an immunoregulatory effect which prevents destruction of infected cells by cytotoxic T-cells.  This immune regulation may predispose to chronicity during perinatal infections and prevent severe liver injury during adult infections.
What are the official names of this protein?
External core antigen, HBeAg, Precore protein, p25.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus precore antigen family.
What are the subcellular locations of this protein?
Secreted. Host nucleus.
Protein: MATRX_RABVR
Sequence: MNVLRKIVKKCRDEDTQKPSPVSAPPYDDDLWLPPPEYVPLKELTSKKNMRNFCVNGEVKACSPNGYSFRILRHILRSFNEIYSGNHRMVGLVKVVVGLALSGAPVPEGMNWVYKLRRTLIFQWADSRGPLEGEELEYSQEITWDDDTEFVGLQIRVSARQCHIQGRIWCINTNSRACQLWSDMSLQTQRSEEDKDSSLLLE
What is the function of this protein?
Plays a major role in assembly, budding and uncoating of virion after membrane fusion.  Completely covers the ribonucleoprotein coil and keep it in condensed bullet-shaped form.  Inhibits viral transcription and stimulates replication.  Plays a major role in early induction of TRAIL-mediated apoptosis in infected neurons.
What are the official names of this protein?
Matrix protein, Phosphoprotein M2.
What is the protein family that this protein belongs to?
Belongs to the lyssavirus matrix protein family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein. Host endomembrane system; Peripheral membrane protein. Host cytoplasm.
Protein: TRPA_AZOSB
Sequence: MSKIQTTFQRLQAQGRKALIPFITAGDPDPTLTVPLMHALVAGGADIIELGVPFSDPMADGPTIQRASERALAQGMTLRKVLQAVREFRSGDADTPVVLMGYANPIEAMGQQAFVAAAREAGVDGALVVDYPPEECVEFAAASKAAGLDPIFLLAPTSSEQRFADVARAGSGYIYYVSLKGVTGAGTLDLDEVARRIPQIRAAVGMPVGVGFGIRDAESARRIGAVADAVVIGSRIIEEIERSPREQACSNVTHFVKGIREALDTLPGVKQ
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: RNB_YERP3
Sequence: MFQDNPLLAQLKQQLHTQTPRVEGVVKGTEKGFGFLEVDGQKSYFIPPPQMKKVMHGDRIIATLHTDKDREIAEPETLVEPFLSRFVGRVQRKDDRLSIVPDHPLLRDAIQCRPVRELTHSFQNGDWAVAEMCRHPLKGDRAFQADLTAFITNGEDHFVPWWVTLARHNLEREAPAMVESALNDAELEREDLTALNFVTIDSASTEDMDDALFVQDNGDGSWLLTIAIADPTAYVVENSELDLTARKRAFTNYLPGFNIPMLPRDLSDNLCSLRPNERRTVLVCRVTITEEGALSNDIRFSAAWVESKAKLVYDDVSDWLEGNNRWQPQDTAIAEQITLLKRICDARSNWRQQHALVFKDRPDYRFLLGEKGEVLDIIVEHRRIANRIVEECMIAANVCAALALRDHLGFGIYNVHTGFDPALVEQAASVLKANGVDADPQALLTLPGFCELRRHLDALPTQFLDSRIRRFQTFAEISTVPGPHFGLGLEAYATWTSPIRKYGDMVNHRLLKAMITGQQAEKPQEEITVQLAERRRLNRMAERDVGDWLYARYLQPQAGTDTRFTAEIIDITRGGLRVRLLDNGAVAFIPAPFIHAVRDEVVCSQETGTVQIKGETVYSQSDKIEVRIAEVRMETRNVIARPVA
What is the function of this protein?
Involved in mRNA degradation.  Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.
What are the official names of this protein?
Exoribonuclease 2, Exoribonuclease II, RNase II, Ribonuclease II.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family. RNase II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOZ_GUITH
Sequence: MKKKYLSVNSNYVLYKTEELLDAASNRYKITVQIANRAKRRRYEDIDLLEEVTLKPIVRAVLEMAEEISQPEIISD
What is the function of this protein?
May be involved in RNA polymerase activity.
What are the official names of this protein?
Putative DNA-directed RNA polymerase subunit omega, PEP, Plastid-encoded RNA polymerase omega subunit, RNA polymerase omega subunit.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: COBQ_CHLAA
Sequence: MQAPVLMVVGTASSVGKSTLVTALCRLAYRRGLRVAPFKAQNMSNNAAVTADGKEIARSTAVQAAAAGIAPTVAMNPILIKPEGQRRSQIIVEGRPWQSLTATDFWQRKAQLWSVVTRNLDHLRATYDLVIAEGAGSPVELNLKPGDIVNMRVARYAQAQTILVGDIDRGGIFAQLLGTLMLLEPEERQLITGCIVNRFRGDPSLFADGVTILEERSGLPVLGVIPWLDDLGLPEEDAVALEQPPVAPAHGLIIAVIRLPTIANFDDFDPLAREPGVVVRYIDHPLELTGAAAVILPGVKHTLAARHWLHERGFDNALREFTGAIVGICGGYQLLGERISDPLAVEGSGGEAAGLGLLPIETIFTTAKQTTQTIACAQVPWAGNEPLQGYEIHMGQSYRRGEAPAFLRIIQRGNTPTSADDGCISSDGRVWGCYLHGIFANDTFRRGWLRRLGWQPPTTPVARADPFDRLADHVAAALGPAVLDRLMRR
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: NUOH_ALBFT
Sequence: MIDTIFALGEGLLAAPWWSAIGWPVVWALIKVTLVLMIVMGAVTYTTLWERRLLAWAQIRMGPNRVGPWGLLQPIADAMKLMTKEVLRPAAAEKFLFYLGPVMTVMPAMAAWAVIPFGPDIALANINAGLLFLMAITSMEVYGVIISGWSSNSKYPFLGALRASSQMVSYEIAMGFCLVVVLMVSASLNLTDIVAGQNKGYFAQIGLNFLSWNWLPLLPIFLIYFISGLAETNRLPFDVIEGESEIVAGHMVEYSGMSWAMFQMAEYANIWLVSVLTTIMFLGGWLSPIDSVMFNWIPGWIWLGLKSFCVVTMFIWVRVSFPRFRYDQIMRLGWKIFIPVSLIWLVVVGGWMQTPWNIWK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ALR_GEOMG
Sequence: MDSRPTIAEIDLAALRHNFEQVQRAVPAGCGILAIVKADAYGHGFMDISRELESLGVTAFGVAFLAEGIQLRKSGIDRPVLILGGVYPGQERKCVGFNLSTAVFSLEQARVLNDTAARLYRKAKIHVKIDTGMGRLGVAAAEAPAFFRELREMKSLELEGIISHFASADELDDDGRRFSDRQAAVFAQSVAEARSLGLDPRYVHIANSAAAFGMDLPFCNLVRPGIVLYGALPSGDFEGKMALRPIMRLQSTVAMLKWVEPGTSISYARRYTAPDRRLIASVPVGYADGYSRALTNRGEVLIRGTRAPVVGTVCMDWIMIDVTSVPGVAVGDEVTLLGCDRQGHCVRAEELASWAGTIPYEIFCGISKRVPRVYLNATR
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: OBG_ACIBC
Sequence: MRFVDEAVITVEAGDGGNGVASFRREKFVPFGGPDGGDGGRGGSIYIQADDDTSTLVDYRYTRKFRAERGKNGAGANCTGRGGEDVVLKVPVGTTIVDTDSGDIIGDLVEDGQRVMVASGGEGGLGNTHFKSSTNRAPRKCTTGTKGEFREIRLELKVLADVGLLGMPNAGKSTFIRAVSAAKPKVADYPFTTMVPNLGVVDADRHRSFVMADIPGLIEGAAEGAGLGIRFLKHLARTRILLHIIDVQPIDGSDPAHNAKAIMNELAKFSPTLAKLPIVLVLNKLDQIAEESREEWCQHILDELQWTGPVFKTSGLLEEGTKEVVYYLMDQIEQQREREVEDPEYAAEVRAFREQLEAETREQTIAAKEAYRAMRKAQRLESMMDDDDDFDDDEDDGDVESIYVRD
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTI_SALTI
Sequence: MQQFEWIHGAWLGLAIMLEIAANVLLKFSDGFRRKCYGILSLAAVLAAFSALSQAVKGIDLSVAYALWGGFGIAATLAAGWVLFGQRLNPKGWVGVILLLAGMVMIKFA
What is the function of this protein?
Catalyzes the excretion of spermidine.
What are the official names of this protein?
Spermidine export protein MdtI.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtI subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MTNN_SALTI
Sequence: MKIGIIGAMEEEVTLLRDKIDNRQTITLGGCEIYTGQLNGTEVALLKSGIGKVAAALGATLLLEHCKPDVIINTGSAGGLASTLKVGDIVVSDEARYHDADVTAFGYEYGQLPGCPAGFKADDKLIAAAESCIRELNLNAVRGLIVSGDAFINGSVGLAKIRHNFPDAVAVEMEATAIAHVCHNFNVPFVVVRAISDVADQQSHLSFDEFLAVAAKQSTLMVETLVQKLAHG
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.  Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: DNMK_BPT5
Sequence: MSVLVGLHGEAGSGKDTVAKLIIDWCNDTYPTCLSRRYSFAKPVYELASVILGVTPEFLGERRGKEIDQWFTVTQSQLERARDVWFKYGIDKFEDFSYVWPIFEEKYLNPQQLISENKEDGLYSLFISPRKMLQLVGTELGRQLVHERIWLIILEQSIAKDDPDVAVITDVRFPNEGELLRETNHLDMDSLLVNVVPAEQKFTIKSDHPSESGIPAKYITHELVNKFDGINNLKLEVYNFCDLELEPLVG
What is the function of this protein?
Allows the synthesis of deoxyribonucleoside triphosphates necessary for the rapid viral DNA replication (PubMed:14711503).  Phosphorylates all four dNMPs (PubMed:5846986).
What are the official names of this protein?
Deoxynucleoside-5'-monophosphate kinase.
Protein: KUNIG_RHIMP
Sequence: MKYLILLAVLGTAFAQRNGFCRLPADEGICKALIPRFYFNTETGKCTMFSYGGCGGNENNFETIEDCQKACGAPERVSDFEGADFKTGCEPAADSGSCAGQLERWFYNVRSGECETFVYGGCGGNDNNYESEEECELVCKNM
What is the function of this protein?
Midgut thrombin inhibitor that plays a major role in keeping the midgut microenvironment at low hemostatic and inflammatory tonus (PubMed:18286181, PubMed:26745503).  Also inhibits FXIa (F11), kallikrein (KLK1), neutrophil elastase (ELANE) and cathepsin G (CTSG), which play a role in the contact pathway of the coagulation cascade (PubMed:18286181, PubMed:26745503).  Also abrogates platelet aggregation by cathepsin G and plasmin, and attenuates tissue factor (F3) pathway inhibitor cleavage by elastase (PubMed:18286181, PubMed:26745503).  In vivo, inhibits thrombosis and promotes bleeding in mice (PubMed:26745503).
What are the official names of this protein?
Boophilin-G2.
What are the subcellular locations of this protein?
Secreted.
Protein: IML2_ASPCL
Sequence: MFRVGSWLYGKKPANASTQSLDSLVELRDPATLILNDDVDGAEDGLAEGTSSFHNLGRGVVAFIRATLGFEQDIMRQASERLNEAETTASVDQHRAQHNSQAPNTYHSAMYTPGTEFALCQAMAQLMGAVVGVLNESLTESIKGFYRLRKAYITLDAILKMEQKYLQESRMATPIESAAPGSIPLSMKRQGSSNLQSSSSSISSAKIKKAASSATTLAAPVENTDLSERLTGLNLSSETLAPGDVKEASTLGPADMLNHDPDSDIFHNQIDIFVHSGSNFCFGILLLLISMVPPAFSKLLSIIGFHGDKERGLRMLWQASKFHNLIGAIAAFSVLGYYNGFVRYCDIMPDSIPGQDEDVQGYPQERLELLLAKMRKQFPKSQLWVLEESRMCGANKNLDRALELLCGGESSPLKQVEALRLFERSLNAMYLHKYELCAASFLECFELNTWSRSLYYYITGSCHLSLYRNALDKDPAKAAEHAELAEKYFRLAPPLAGKKRFMARQLPFDVFVARKVAKWEARAKDWKVPLVDAVGVDPIEEMIFFWNGHSRMTDEHLLESLQKLAWCESSANKTWSREGPEEKAILKLLRAAVFRSLRKHSQAKDLLEDILSQDRNLFKGHLKDDWICPVAHFEMAANMWMERPTYIAIHGGSKEFTDPEATEPADSSKSLEYEREKVHKCKEYLEKAAKWESYELDARIGLKVTAAMEAVQKWENTHPPA
What is the function of this protein?
Inclusion body (IB) resident protein that interacts strongly with lipid droplet (LD) proteins.  Involved in LD-mediated IB clearing after protein folding stress, probably by enabling access to the IBs of an LD-stored soluble sterol derivative that acts as chaperone in inclusion clearing.
What are the official names of this protein?
Inclusion body clearance protein iml2.
What is the protein family that this protein belongs to?
Belongs to the IML2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localized exclusively in cytoplasmic inclusion bodies under protein folding stress conditions.
Protein: FTR_METFK
Sequence: MIINGVTIDDTFAEAFGMRGTRVIITAQNLRWAYNAARAMTGFATSVIACGVEAGIERELTPEETPDGRPGVSILMFAMSSAVLIKQLETRMGQCVLTCPTAAAFSGIDEGYPEITRINLGKNLRFFGDGFQISKVFNGKRYWRVPVMDGEFLTEETTGMIRSVGGGNFLILAESQPQALAACEAAIDAMSKIPNVIMPFPGGVVRSGSKVGSKYKALIASTNDAFCPTLKGITKTELSPEIESVMEIVIDGLTDPDIRVAMRAGIAAACELGAKNGIKRISAGNYGGKLGPYHFKLREIMA
What is the function of this protein?
Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT).
What are the official names of this protein?
Formylmethanofuran--tetrahydromethanopterin formyltransferase, Ftr, H4MPT formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the FTR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIG_ECO5E
Sequence: MNAEKSPVNHNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLRLSYIAERAGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTLNRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLGWVDQTSLKERHITGLHYNPITNTFKLGPGVDVNYMLHTQNK
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-octaprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone-8 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: RHEX_HUMAN
Sequence: MLTEVMEVWHGLVIAVVSLFLQACFLTAINYLLSRHMAHKSEQILKAASLQVPRPSPGHHHPPAVKEMKETQTERDIPMSDSLYRHDSDTPSDSLDSSCSSPPACQATEDVDYTQVVFSDPGELKNDSPLDYENIKEITDYVNVNPERHKPSFWYFVNPALSEPAEYDQVAM
What is the function of this protein?
Acts as a signaling transduction factor of the EPO-EPOR signaling pathway promoting erythroid cell differentiation (PubMed:25092874).
What are the official names of this protein?
Regulator of hemoglobinization and erythroid cell expansion protein, Regulator of human erythroid cell expansion protein.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RELE1_CAUVC
Sequence: MTFTVLVSVRAKRDFNRLIVWLVERDPRAAARLGPLLEAALDSLTEAPSRGRSVGPTTREISIPFGQSAYVIRYRLLGSSVHVTRIWHGLEQR
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  Its toxic effect is neutralized by coexpression with cognate antitoxin RelB1 but no other ParD or RelB antitoxin.
What are the official names of this protein?
Toxin RelE1.
What is the protein family that this protein belongs to?
Belongs to the RelE toxin family.
Protein: MATK_PICAB
Sequence: MDEFHRYGKEDSSWQQCFLYPLFFQEDLYAISHDHYLDGSSSSEPMEHLSSNDQFSFLTVKRLIGQIRQQNHSIVLFVNCDPNPLVDRKKSSYSESVLEGLTLVLEVPFSIRSKYSVEGMNEWKSFRSIHSIFPFLEDKFPHSNYVSDTRIPYSIHPEILVRTFRRWIGDAPSLHPLRSILYEYRNSSESLQRSIIVVPKVNTRFFLFLWNNYVYECESILVSLLKRSSHSRSLSHGSFPQRTHFHRKIKNIFLFSRRNSFQSIWSLKDPNIHYVRYGERSIIAIKGTHLLVKKYRYYLPIFRQCYFHLWNEPYRVCFHQLSKNCSSSLGYFLRVRMKPLLVKTKMLDELFIADLITDEFDPIVPIVPIIGLLSREKFCDISGRPISKLSWTSLTDDDILDRFDRIWRNLFHYYSGSFGRDGLYRIKYILSLSCAKTLACKHKSTIRVVRKELGPELFKKSFSKERELDSPPFSSKAAARSQRERIWHSDIPQINPLAHSWQKIQDLKIENLFDQ
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ACS1_KLULA
Sequence: MSPAVDTASTAKDPISVMKSNASAAAADQIKTHEYEHLTSVPIVQPLPITDRLSSEAAQKYKPNLPGGFEEYKSLHKESLENPAKFYHERAQLLNWFKPYDQVFIPDTEGKPTFENNAWFTNGQLNACYNLVDRHAFTQPNKVAILYEADEPGQGYSLTYAELLEQVCKVAQILQYSMNVKKGDTVAVYMPMIPQALITLLAITRIGAIHSVVFAGFSSNSLRDRINDAYSKTVITTDESKRGGKTIETKRIVDEALKDTPQVTNVLVFKRTHNENIKYIPGRDLDWDEEVKKYKSYTPCEPVDSEHPLFLLYTSGSTGAPKGVQHSTAGYLLQALLSMKYTFDIQNDDIFFTAGDIGWITGHTYCVYGPLLQGCTTLVFEGTPAYPNFSRYWEIVDKYQVTQFYVAPTALRLLKRAGDSFTEGFSLKSLRSLGSVGEPIAAEVWEWYSEKIGKNELPIVDTYWQTESGSHLVTPLAGGATPMKPGAAAFPFFGIDLAVLDPTTGIEQTGEHAEGVLAIKRPWPSFARTIWKNNDRFLDTYLKPYPGYYFTGDGVARDKDGFFWILGRVDDVVNVSGHRLSTAEIEAAIIEDDMVAECAVVGFNDELTGQAVAAFVVLKNKSSLTAASESELQDIKKHLIITVRKDIGPFAAPKLIVLVDDLPKTRSGKIMRRILRKILAGESDQLGDVSTLSNPGIVKHLIDSVKL
What is the function of this protein?
May be required for assimilation of ethanol and acetate.
What are the official names of this protein?
Acetyl-coenzyme A synthetase 1, Acetate--CoA ligase 1, Acyl-activating enzyme 1.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Microsome. Endoplasmic reticulum.