PharMolix/UniProtQA huggingface dataset:
Protein: FKBP4_CANGA
Sequence: MSDMLPLAMYALNVEPYTHTPAVLLDTPVTVRITMAAIDPEPFDEDKKPSTLRIIRRNPVYLDAGEVDEEKLIEELEGDEAAEDGDEASDDDKEEEDEDEDVDEDDEDDDEDDDGEDEYEECVVVTLSPETRCQQAIDITIAPEEDVQFLVTGSYTISLTGNYVKHPFDEPLEDLYSDEDSEEYSDDELDQEIEEDDELDHDEASSEESDEDQEFYDAISEGDEDIDEQLAKLEETSDVEAHLEDLIAKDNKKKRKQEQLDEQPETKKSKKTKDEKNTKATENEKKNKAQVLEGGVIIEDRKIGEGPKAKKGSKVGMRYIGKLKNGKVFDKNTSGKPFYFKLHRGEVIKGWDIGVTGMAIGGERRIVIPAPYAYGKQTLPGIPANSELTFDVKLVSLK
What is the function of this protein?
PPIase that acts as a histone chaperone.  Histone proline isomerase that increases the rate of cis-trans isomerization at prolines on the histone H3 N-terminal tail.  Proline isomerization influences H3 methylation thereby regulating gene expression.
What are the official names of this protein?
FK506-binding protein 4, Histone proline isomerase, Peptidyl-prolyl cis-trans isomerase, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. FKBP3/4 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RR8_LOBMA
Sequence: MGKDTIADIITSIRNADMNRKGTVRIGSTNITESIVKILLREGFIENVRKHRENNQYFLILTLRHRRNKKESHKTILNLKRISRPGLRIYSNSQRIPRILGGIGIVILSTSQGIMTDREARLKRIGGEILCYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TACHY_DROME
Sequence: MRPLSGLIALALLLLLLLTAPSSAADTETESSGSPLTPGAEEPRRVVKRAPTSSFIGMRGKKDEEHDTSEGNWLGSGPDPLDYADEEADSSYAENGRRLKKAPLAFVGLRGKKFIPINNRLSDVLQSLEEERLRDSLLQDFFDRVAGRDGSAVGKRAPTGFTGMRGKRPALLAGDDDAEADEATELQQKRAPVNSFVGMRGKKDVSHQHYKRAALSDSYDLRGKQQRFADFNSKFVAVRGKKSDLEGNGVGIGDDHEQALVHPWLYLWGEKRAPNGFLGMRGKRPALFE
What is the function of this protein?
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.  Stimulates gut muscle contractions (PubMed:10801863).  Required for the response to the male sex pheromone CH503 which is transferred from males to females during mating and inhibits courtship behavior by other males (PubMed:26083710).  The Gr68a gustatory receptor is required for detection of the pheromone and Gr68a-expressing neurons in the male foreleg relay signals to the suboesophageal zone (SEZ) which leads to courtship suppression through release of tachykinin from a cluster of 8-10 neurons in the SEZ (PubMed:26083710).
What are the official names of this protein?
Tachykinins, dTk.
What is the protein family that this protein belongs to?
Belongs to the tachykinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CAPP_EDWI9
Sequence: MNEQYSAMRGNVSMLGKLLGDTIKDALGEEILDRVETIRRLSKSSRAGNEASRQALLNTLQNLSNDELLPVARAFSQFLNLANVAEQYHRISPHGEAASNPDALYHLFTRLKNKNLDEAQIRQAVDNLSIELVLTAHPTEIARRTLIHKLVEVNTCLSQLDHDDLADYERHQIMRRLRQLVAQSWHTDEIRKNRPTPIDEAKWGYAVVENSLWEGVPAFLREFNEQLEKSLGYQLPVEAVPVRFTAWMGGDRDGNPNVTAEVTRRALLLSRWKAAELFLRDVQVLVSELSMTVCTPELRALAGEHTQEPYREVLKRLRQQLNNTLTYLDARLRGERLPRPADLLVSNDQLWQPLHTCYRSLKACGMGIIANGQLLDTLRRVHCFGVPLVRIDIRQESTRHTEALAELTRYLGLGDYETWSEEDKQTFLLRELNSKRPLVPRHWTPSPETKEVFDTCQVIAEAPAGAIAAYVISMARTPSDVLAVHLLLKEAGCPYNLPVVPLFETLDDLNNAEAVMTQLLSIDWYRGFIQGKQMVMIGYSDSAKDAGVMAASWAQYRAQEALVRVCDNAGIALTLFHGRGGSIGRGGAPAHDALLSQPPGSLKSGLRVTEQGEMIRFKLGLPEIAVSSLTLYTSAILEANLLPPPAPKQEWRDVMDELSQTSCALYRRYIRKNPDFVPYFRSATPELELGKLPLGSRPAKRRPSGGVESLRAIPWIFAWTQNRLMLPAWLGAGTALEEAMTEGHRGTLENMYRSWPFFTTRIDMLEMVFAKSDLWLAEYYDQRLVDPALWPLGTELRQQVQRDIQAVLTIADTDHLMADLPWAAESIALRNVYTDPLNVLQAELLYRSRHQEQPDANVEQALMVTIAGVAAGMRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: DF153_ARATH
Sequence: MKNVSQVSVAVLLIFSILVLGIGVQGKVPCLSRMFNKNNTCSFLRCEANCARKYKGYGDCRPGDRPHDKKDSLFCFCNYPC
What are the official names of this protein?
Defensin-like protein 153, Low-molecular-weight cysteine-rich protein 31, Protein LCR31.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: WTF15_SCHPO
Sequence: MSNNYTSLSSSLDEEMGLKAGHEIDLEGSPPSEHNSEEKSTLPSNSDILTSANPVSQASETPDHSIESNTGSTQSPTSHSLLLKFSFCIVYYSYFAIVVLGCVLPFEHTHTFLIAFLVIFGIISVILFSGSIYYYETWTKTVKHFLKKVISPFKKEYIVCAFLKTFVFYGLLKTIEHFLVLLSGDKWGWKCSTLSSILTPVSCISFCLNESVQLRSCSTHLFINTVAWIKSLGGGKNAFENNYNQLNETSPEDLV
What is the function of this protein?
May act in meiotic drive.
What are the official names of this protein?
Wtf element wtf15.
What is the protein family that this protein belongs to?
Belongs to the WTF family.
What are the subcellular locations of this protein?
Spore membrane; Multi-pass membrane protein.
Protein: ISPF_BUCA5
Sequence: MRIGYGFDLHAFGSTKPLIIGGVLIPCEKGLIAHSNGDLLIHSLIDALLGATAMGDIGSFFPSNNYIYKNIDSRILLKKIWNKIILLNYDICNIDITIIAEYPKMLPYIFFMRSNLSLDLNTEIDNISIKSTTSKKIGCIGRKEAIACHSIVMLIKNKKCI
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: ATD2B_HUMAN
Sequence: MVNTRKSSLRLLGSKSPGPGPGPGAGAEPGATGGSSHFISSRTRSSKTRAASCPAAKAGGSGGAGVTLDEARKVEVDGSLSDSHVSPPAKRTLKQPDSVCKDKSKSRSTGQREEWNLSTGQARLTSQPGATLPNGHSGLSLRSHPLRGEKKGDGDLSCINGDMEVRKSCRSRKNRFESVNQSLLFDQLVNSTAEAVLQEMDNINIRQNRRSGEVERLRMWTDTEFENMDMYSRVKRRRKSLRRNSYGIQNHHEVSTEGEEEESQEEDGDIEVEEAEGEENDRPYNLRQRKTVDRYQAPPIVPAHQKKRENTLFDIHRSPARRSHIRRKKHAIHSSDTTSSDEERFERRKSKSMARARNRCLPMNFRAEDLASGILRERVKVGASLADVDPMNIDKSVRFDSIGGLSHHIHALKEMVVFPLLYPEIFEKFKIQPPRGCLFYGPPGTGKTLVARALANECSQGDKKVAFFMRKGADCLSKWVGESERQLRLLFDQAYLMRPSIIFFDEIDGLAPVRSSRQDQIHSSIVSTLLALMDGLDNRGEIVVIGATNRLDSIDPALRRPGRFDREFLFNLPDQKARKHILQIHTRDWNPKLSDAFLGELAEKCVGYCGADIKALCTEAALIALRRRYPQIYASSHKLQLDVSSIVLSAQDFYHAMQNIVPASQRAVMSSGHALSPIIRPLLERSFNNILAVLQKVFPHAEISQSDKKEDIETLILEDSEDENALSIFETNCHSGSPKKQSSSAAIHKPYLHFTMSPYHQPTSYRPRLLLSGERGSGQTSHLAPALLHTLERFSVHRLDLPALYSVSAKTPEESCAQIFREARRTVPSIVYMPHIGDWWEAVSETVRATFLTLLQDIPSFSPIFLLSTSETMYSELPEEVKCIFRIQYEEVLYIQRPIEEDRRKFFQELILNQASMAPPRRKHAALCAMEVLPLALPSPPRQLSESEKSRMEDQEENTLRELRLFLRDVTKRLATDKRFNIFSKPVDIEEVSDYLEVIKEPMDLSTVITKIDKHNYLTAKDFLKDIDLICSNALEYNPDKDPGDKIIRHRACTLKDTAHAIIAAELDPEFNKLCEEIKEARIKRGLSVTSEQINPHSTGARKTETRVEEAFRHKQRNPMDVWHNSANKCAFRVRRKSRRRSQWGKGIIKKRKVNNLKKDEEDTKFADYENHTEDRKLLENGEFEVSTDCHEENGEETGDLSMTNDESSCDIMDLDQGQRLNNGAGTKENFASTEEESSNESLLVNSSSSLNPEQTSRKETFLKGNCLNGEASTDSFEGIPVLECQNGKLEVVSFCDSGDKCSSEQKILLEDQSKEKPETSTENHGDDLEKLEALECSNNEKLEPGSDVEVKDAELDKEGASKVKKYRKLILEQAKTTSLELVPEEPSEPVPPLIVDRERLKKLLDLLVDKSNNLAVDQLERLYSLLSQCIYRHRKDYDKSQLVEEMERTVHMFETFL
What are the official names of this protein?
ATPase family AAA domain-containing protein 2B.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Nucleus. Note=Partially localizes to replication sites.
Protein: SYE_CHLPB
Sequence: MQATPGQRVRTRFAPSPTGHLHVGGLRTALYNYLYAKSMGGDFIVRIEDTDQARKVEGAERSLLNTLEVTGIVPDESFIHGGNFGPYVQSERLGIYSKYCEQLLEQKQAYYCFSTAEELEANRKLQMKQGMQPKYDRKWLPEEMGGNMPESEIRRKREEGAPFVVRMKVPDYISIMFEDMIRGPIEFDSATVDDQVLMKSDGFPTYHFASIIDDHLMEISHVIRGEEWLSSMPKHILLYEFFGWEPPKVAHLPLLLNPDRSKLSKRQGDVAAEDFISKGYSPEAIINFVALLGWNEGEGCEREVYSLDELKDKFTLRRVGKAGAVFNVEKLGWLEKQYIKARPASEIISAIKPLLQAELAKKETGMDADRLVSDDYLGQVIELMRERVNFEHEFISFSRYFYFDPEEFDEKAVAKRWVDDTNEVLGEFIEVLENTADFSADNIEAALKAFVAPREKKPAFLIHPVRILTSGVGFGPSLYHMLEVLGKETVIRRLRKGIGVVGK
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_SULNB
Sequence: MKINVIIIDKKGKDQLYAPLIEHYKKISKPFAKVEVIELFDKEIAKAQDISPEAAQRSYSKALEKYLGSGINIALDPASKEVDSFEFAKLLKDSVTVNFYIGGAYGFERDFLSKCNNAVSFGKITLSHKLVKVVLMEQIFRGLTINHNHPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_CHLTE
Sequence: MNIISVGVNHKTAPIEIRERIALSEVQNKELVTDLVSSGLASEAMVVSTCNRTELYVVPGMPEVNCDYLKDYIISYKNARNAVRPEHFFSRFYCGTARHLFEVSCAIDSLVLGEGQILGQVKNAYRIAAEVGTAGILLTRLCHTAFSVAKKVKTRTKLMEGAVSVSYAAVELAQKIFSNLSMKKVLLIGAGETGELAAKHMYAKNARNIVITNRTQSKAEALAEELGTNRVLPYESYKEHLHEFDIIITAVSTKEYILNAAEMQQSMAKRRLKPVIILDLGLPRNVDPEVGALQNMFLKDIDALKHIIDKNLERRRAELPKVKAIIDEELVAFGQWLNTLKVRPTIVDLQSKFLEIKEKELERYRYKVSEEELRRMEHLTDRILKKILHHPIKMLKAPVDTADNIPSKVNLVRNIFDLEEPNQSLQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: TYSY_SALPB
Sequence: MKQYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLQEGFPLVTTKRCHLRSIIHELLWFLQGDTNIAYLHENNVTIWDEWADENGDLGPVYGKQWRAWPTPDGRHIDQIATVLSQLKNDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLDVGDFVWTGGDTHLYSNHMEQTHLQLSREPRALPKLVIKRKPDSLFDYRFDDFEIEGYDPHPGIKAPVAI
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YFM8_SCHPO
Sequence: MSSASMFGSLKTNAVDESQLKARIGVLALQGAFIEHINIMNSIDGVISFPVKTAKDCENIDGLIIPGGESTTIGKLINIDEKLRDRLEHLVDQGLPIWGTCAGMILLSKKSRGGKFPDPYLLRAMDIEVTRNYFGPQTMSFTTDITVTESMQFEATEPLHSFSATFIRAPVASTILSDDINVLATIVHEGNKEIVAVEQGPFLGTSFHPELTADNRWHEWWVKERVLPLKEKKD
What are the official names of this protein?
Uncharacterized glutaminase C222.08c.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HXA1_XENLA
Sequence: AYAHSSCGSNYGMQNFSPGYSHFPIHQETEVSSGFPQSVYSGNIASSVVQHQQHQSYIEGSAHYIHHSYGPEQNLSVANYNNNVASLHISQREVCHSPSSETSPGPTQTFDWMKVKRNPPKTGKAGEYGYAGQPNTARTNFTTKQLTELEKEFHFNKYLTRARRVEIAAALQLNETQVKIWFQNRRMKQKKREKEGLLPISPSTSTGSDEKSEELSEKSNSSPCAPSPASSTSDHLSASG
What is the function of this protein?
Sequence-specific transcription factor.  Part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.  Acts on the anterior body structures.  Seems to act in the maintenance and/or generation of hindbrain segments.
What are the official names of this protein?
Homeobox protein Hox-A1, Hox.lab2.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family. Labial subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: STP1_RAT
Sequence: MSTSRKLKTHGMRRGKNRAPHKGVKRGGSKRKYRKSSLKSRKRGDDASRNYRSHL
What is the function of this protein?
Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals.  In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.
What are the official names of this protein?
Spermatid nuclear transition protein 1, STP-1, TP-1, Testis-specific basic protein.
What is the protein family that this protein belongs to?
Belongs to the nuclear transition protein 1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Loaded onto the nucleosomes of condensing spermatids.
Protein: UL24_EHV1V
Sequence: MKRRQRLTARSRLRAGIRCHNRFYNAMVQDLASAKRNGVYGERLAPLFSELVPAETLKTALGVSLAFEVNLGQRRPDCVCTVQFGKGSDAKGVCILIELKTCRFSKNMNTASKNLQRKGGMRQLHDSCRLLARTLPPGSGEIVLAPVLVFVAQRGMRVLRVTRLSPQVVYSNAAVLSCTISRLAEYAPPVSAKSTRRRCVAKGTKAKAFSTKAAAEPVPSITPAQPSAAAAVVSLFPAAVPANTTNAAAVHQPVAVSHVNPLAWVASLFSPK
What is the function of this protein?
May participate in nuclear egress of viral particles.  Plays a role in the dispersal of several host nucleolar proteins including NCL/nucleolin and NPM1.  Since deletion of host NCL/nucleolin negatively impact on nuclear egress, UL24 supposedly acts on this process through its effect on host nucleoli (By similarity).
What are the official names of this protein?
Protein UL24 homolog.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae UL24 family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Host nucleus, host nucleolus. Host Golgi apparatus.
Protein: CLPP1_AGRFC
Sequence: MRETMQLVPMVVEQSSRGERSFDIYSRLLRERIIFLNGEVDDTVSALVCAQLLFLEAENPKKPIHLYINSPGGMVTSGFAMYDTMRYIRAPVHTLCMGTARSMGSFLLMAGEPGTRAALPNASILIHQPSGGFQGQASDMLIHAEEIRQTKHRMTRLYAEHCGRSYEEFETAMDRDRFMTVQEALEWGLIDRILEVREDAAA
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 1, Endopeptidase Clp 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNN_ECO7I
Sequence: MKIGIIGAMEEEVTLLRDKIENRQTISLGGCEIYTGQLNGTEVALLKSGIGKVAAALGATLLLEHCKPDVIINTGSAGGLAPTLKVGDIVVSDEARYHDADVTAFGYEYGQLPGCPAGFKADDKLIAAAEACIAELNLNAVRGLIVSGDAFINGSVGLAKIRHNFPQAIAVEMEATAIAHVCHNFNVPFVVVRAISDVADQQSHLSFDEFLAVAAKQSSLMVESLVQKLAHG
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.  Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: AMPA_SALHS
Sequence: MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGKERELDERQYKQVIQKTINTLNDTGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFNVPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNVITRVIGEQQMRELGMNAYLAVGHGSQNESLMSVIEYKGNPSEDARPIVLVGKGLTFDSGGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVLAGCENMPGGRAYRPGDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHITGLMSNHNPLAHELIGASEQAGDRAWRLPLGDEFQEQLESNFADMANIGGRPGGAITAGCFLSRFTRKYNWAHLDIAGTAWRSGKAKGATGRPVALLSQFLLNRAGFNGEE
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINE_PSEA8
Sequence: MSLLDFFRSRKSQNSASIAKERLQIIVAHERGQRAQPDYLPQLQKDLLEVIRKYVPIDQEQIQVELENQGNCSILELNITLPDR
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: DERI1_MYCS2
Sequence: MALRVVVGADDAGYEYKEALKGDLAADDRVTEVIDVGVGADEDTAYPHVAVAAARLIAEGKADRALLVCGTGLGVAISANKVPGIRAVTAHDSFSVERSVLSNNAQVLCFGQRVVGLELARRLAREWLGYEFDPTSKSAEKVQAICGYEPATS
What is the function of this protein?
Catalyzes the isomerization of D-erythrulose-4P to D-erythrose-4P.  Involved in the degradation pathways of erythritol and D-threitol, that allow M. smegmatis to grow on these compounds as the sole carbon source.
What are the official names of this protein?
D-erythrulose-4-phosphate isomerase 1.
What is the protein family that this protein belongs to?
Belongs to the LacAB/RpiB family.
Protein: P4K2B_MOUSE
Sequence: MAEACEPTRPSEDEDEEREPLLPRVAWAQPRRVAPGSAVRMQADEGADVLREPATDEPPAVSGEGSISASLSTELDRTRTTSSETNTFLEDPEFADIVLKAEQAIEIGVFPERISQGSSGSYFVKDSKRNIIGVFKPKSEEPYGQLNPKWTKYVHKVCCPCCFGRGCLLPNQGYLSEAGAYLVDVKLNLGIVPKTKVVWLVSETFNYSAIDRAKSRGKKYALEKVPKVGRKFHRIGLPPKVGSFQLFVKDYKEAEYWLRRFEAEPLPENIRKQFQSQFEKLVILDYIIRNTDRGNDNWLVKYDEMKYAKKIESEESNWIDNKQLLIKIAAIDNGLAFPFKHPDEWRAYPFHWAWLPQAKVPFSEETRNLILPYISDMNFVQDLCEDLYELFKTDKGFDRAAFENQMSVMRGQILNLTQALRDGKSPMQLAQMPCVIVECSKSGSQGRVVHLGSSFTQTVHCRKPFFSSW
What is the function of this protein?
Together with PI4K2A and the type III PI4Ks (PIK4CA and PIK4CB) it contributes to the overall PI4-kinase activity of the cell.  This contribution may be especially significant in plasma membrane, endosomal and Golgi compartments.  The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3).  Contributes to the production of InsP3 in stimulated cells and is likely to be involved in the regulation of vesicular trafficking.
What are the official names of this protein?
Phosphatidylinositol 4-kinase type 2-beta, Phosphatidylinositol 4-kinase type II-beta.
What is the protein family that this protein belongs to?
Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Golgi apparatus membrane; Peripheral membrane protein. Endoplasmic reticulum membrane. Cell membrane. Early endosome membrane. Note=Mainly cytosolic, association with membranes of the Golgi, endoplasmic and plasma membrane is stimulated by active RAC1. Association with early endosomes has not been confirmed.
Protein: Y329_PSEAE
Sequence: MAAKFHLKKAKDGQFHFNLHAANGEIILTSELYKAKDSALGGIESVRKNSQRDGAFEVKPANNGKFHFVLKATNGQVVGQSQLYASQANAEAGVQSVKRATPEAGLSDES
What are the official names of this protein?
UPF0339 protein PA0329.
What is the protein family that this protein belongs to?
Belongs to the UPF0339 family. Duplicated subfamily.
Protein: NR1H4_HUMAN
Sequence: MVMQFQGLENPIQISPHCSCTPSGFFMEMMSMKPAKGVLTEQVAGPLGQNLEVEPYSQYSNVQFPQVQPQISSSSYYSNLGFYPQQPEEWYSPGIYELRRMPAETLYQGETEVAEMPVTKKPRMGASAGRIKGDELCVVCGDRASGYHYNALTCEGCKGFFRRSITKNAVYKCKNGGNCVMDMYMRRKCQECRLRKCKEMGMLAECMYTGLLTEIQCKSKRLRKNVKQHADQTVNEDSEGRDLRQVTSTTKSCREKTELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFLILTEMATNHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPSGHSDLLEERIRNSGISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLLDVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLCEIWDVQ
What is the function of this protein?
Promotes transcriptional activation of target genes ABCB11/BSEP (inducible by unconjugated CDCA, ACA and DCA), NR0B2/SHP (inducible by unconjugated CDCA, ACA and DCA), SLC51B/OSTB (inducible by unconjugated CDCA and DCA) and FABP6/IBAP; most efficient isoform compared to isoforms 1 to 3; not inducible by taurine- and glycine-amidated CDCA.
What are the official names of this protein?
Bile acid receptor, Farnesoid X-activated receptor, Farnesol receptor HRR-1, Nuclear receptor subfamily 1 group H member 4, Retinoid X receptor-interacting protein 14, RXR-interacting protein 14.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR1 subfamily.
What are the subcellular locations of this protein?
Nucleus. SUBCELLULAR LOCATION: [Isoform 1]: Nucleus. SUBCELLULAR LOCATION: [Isoform 2]: Nucleus. SUBCELLULAR LOCATION: [Isoform 3]: Nucleus. SUBCELLULAR LOCATION: [Isoform 4]: Nucleus.
Protein: DXS_SHIDS
Sequence: MSFDIAKYPTLALVDSTQELRLLPKESLPKLCDELRRYLLDSVSRSSGHFASGLGTVELTVALHYVYNTPFDQLIWDVGHQAYPHKILTGRRDKIGTIRQKGGLHPFPWRGESEYDVLSVGHSSTSISAGIGIAVAAEKEGKNRRTVCVIGDGAITAGMAFEAMNHAGDIRPDMLVVLNDNEMSISENVGALNNHLAQLLSGKLYSSLREGGKKVFSGVPPIKELLKRTEEHIKGMVVPGTLFEELGFNYIGPVDGHDVLGLITTLKNMRDLKGPQFLHIMTKKGRGYEPAEKDPITFHAVPKFDPSSGCLPKSSGGLPSYSKIFGDWLCETAAKDNKLMAITPAMREGSGMVEFSRKFPDRYFDVAIAEQHAVTFAAGLAIGGYKPIVAIYSTFLQRAYDQVLHDVAIQKLPVLFAIDRAGIVGADGQTHQGAFDLSYLRCIPEMVIMTPSDENECRQMLYTGYHYNDGPSAVRYPRGNAVGVELTPLEKLPIGKGTVKRRGEKLAILNFGTLMPEAAKVAESLNATLVDMRFVKPLDETLILEMAASHEALVTVEENAIMGGAGSGVNEVLMAHRKPVPVLNIGLPDFFIPQGTQEEMRAELGLDAAGMEAKIKAWLA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: LEG7_RAT
Sequence: MSATHHKTPLPQGVRLGTVMRIRGVVPDQAGRFHVNLLCGEEQEADAALHFNPRLDTSEVVFNTKQQGKWGREERGTGIPFQRGQPFEVLIITTEEGFKTVIGDDEYLHFHHRMPSSNVRSVEVGGDVQLHSVKIF
What is the function of this protein?
Could be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control.  Pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release (By similarity).
What are the official names of this protein?
Galectin-7, Gal-7.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Secreted. Note=May be secreted by a non-classical secretory pathway.
Protein: Y514_YERPA
Sequence: MYDNLKSLGITQPEDVDRYSLRQEANNDILKIYFRKDKGEFFAKSVKFKYPRQRKTVVSDNASHGYKEINEINPNLRYVIDELDQLCKRDQIEVDLKRKILDDLRHLESVVTNKIAEIEADLEKLTNGR
What are the official names of this protein?
UPF0325 protein YPA_0514.
What is the protein family that this protein belongs to?
Belongs to the UPF0325 family.