PharMolix/UniProtQA huggingface dataset:
Protein: CO1A1_MOUSE
Sequence: MFSFVDLRLLLLLGATALLTHGQEDIPEVSCIHNGLRVPNGETWKPEVCLICICHNGTAVCDDVQCNEELDCPNPQRREGECCAFCPEEYVSPNSEDVGVEGPKGDPGPQGPRGPVGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFASQMSYGYDEKSAGVSVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGGSGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGPPGTAGARGNDGAVGAAGPPGPTGPTGPPGFPGAVGAKGEAGPQGARGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPSGPPGPKGNSGEPGAPGNKGDTGAKGEPGATGVQGPPGPAGEEGKRGARGEPGPSGLPGPPGERGGPGSRGFPGADGVAGPKGPSGERGAPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPAGPPGARGQAGVMGFPGPKGTAGEPGKAGERGLPGPPGAVGPAGKDGEAGAQGAPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGNNGAPGNDGAKGDTGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGARGLTGPIGPPGPAGAPGDKGEAGPSGPPGPTGARGAPGDRGEAGPPGPAGFAGPPGADGQPGAKGEPGDTGVKGDAGPPGPAGPAGPPGPIGNVGAPGPKGPRGAAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPVGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGSPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGSSGERGPPGPMGPPGLAGPPGESGREGSPGAEGSPGRDGAPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKNGDRGETGPAGPAGPIGPAGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGSPGSPGEQGPSGASGPAGPRGPPGSAGSPGKDGLNGLPGPIGPPGPRGRTGDSGPAGPPGPPGPPGPPGPPSGGYDFSFLPQPPQEKSQDGGRYYRADDANVVRDRDLEVDTTLKSLSQQIENIRSPEGSRKNPARTCRDLKMCHSDWKSGEYWIDPNQGCNLDAIKVYCNMETGQTCVFPTQPSVPQKNWYISPNPKEKKHVWFGESMTDGFPFEYGSEGSDPADVAIQLTFLRLMSTEASQNITYHCKNSVAYMDQQTGNLKKALLLQGSNEIELRGEGNSRFTYSTLVDGCTSHTGTWGKTVIEYKTTKTSRLPIIDVAPLDIGAPDQEFGLDIGPACFV
What is the function of this protein?
Type I collagen is a member of group I collagen (fibrillar forming collagen).
What are the official names of this protein?
Collagen alpha-1(I) chain, Alpha-1 type I collagen.
What is the protein family that this protein belongs to?
Belongs to the fibrillar collagen family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: RPP29_PONAB
Sequence: MKSVIYHALSQKEANDSDVQPSGAQRAEAFVRAFLKRSTPRMSPQAREDQLQRKAVVLEYFTRHKRKEKKKKAKGLSARQRRELRLFDIKPEQQRYSLFLPLHELWKQYIRDLCNGLKPDTQPQMIQAKLLKADLHGAIISVTKSKCPSYVGITGILLQETKHIFKIITKEDRLKVIPKLNCVFTVEIDGFISYIYGSKFQLRSSERSAKKFKAKGTIDL
What is the function of this protein?
Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein subunit p29.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: DSBB_PSYIN
Sequence: MLLFFVILGIFVLTILKAISKQRWSWLLLAASALSLELSALYFQHVMQLEPCVMCVYERLAMLGILLAGLIGASSPNNVFIRLSAFLLWGISAVWGILLAIKHTDYQLHPSPFFTCDFFPNFPAWAPLHEWLPWLFNPTGDCSDIVWQFLGYSMPQWLIVSFSLYTLLFIIFAISAVLKTKKQLF
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by oxidizing the DsbA protein.
What are the official names of this protein?
Disulfide bond formation protein B, Disulfide oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the DsbB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GCYA1_CANLF
Sequence: MFCTKLKDLKITGECPLSLLAPGQVPKEPGEEVAGTSESGKATLPICQDVPEKNVQRSLPQRKTSRSRVYLHTLAESICKLIFPELERLNLALQRTLAKHKIKESRKSLEREDLEKIITDQAIAAGVPVEIVKESLGEELFKICYEEDEHILGVVGGTLKDFLNSFSTLLKQSSHCQEAEKRGRFEDASILCLDKDHDFLNVYYFFPKRITSLILPGIIKAAAHILYETEVEVSLLPPCFRNDCSEFVNQPYLLYSLHVKSTKPSLSPGKPQSSLVIPASLFCKTFPFHFMFDKDMTILQFGNGIRRLMNRRDFQGKPHFEEYFEVLTPKINQTFSGIMTMLNMQFVVRVRRWDNSVKKSSRVMDLKGQMIYIVESSAILFLGSPCVDRLEDFTGRGLYLSDIPIHNALRDVVLIGEQARAQDGLKKRLGKLKATLEQAHQALEEEKKKTVDLLCSIFPSEVAQQLWQGQVVQAKKFSNVTMLFSDIVGFTAICSQCSPLQVITMLNALYTRFDQQCGELDVYKVETIGDAYCVAGGLHKESDTHAAQIALMALKMMELSDEVMSPHGEPIKMRIGLHSGSVFAGVVGVKMPRYCLFGNNVTLANKFESCSIPRKINVSPTTYRLLKDCPGFVFTPRSREELPPNFPSEIPGICHFLEAYEPATNSKPWFQKKDVEDGNANFLGKASGID
What are the official names of this protein?
Guanylate cyclase soluble subunit alpha-1, GCS-alpha-1, Guanylate cyclase soluble subunit alpha-3, GCS-alpha-3, Soluble guanylate cyclase large subunit.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPD_STAEQ
Sequence: MKKPDIQQLKDIVNNSNQIVFFTGAGVSVASGIPDFRSMGGLYDEISKDGQSPEYLLSIDHLHDNKESFINFYHERLLIADKKPNIVHQWIAQLENQQKSLGVITQNIDGLHEDAGSHNIDELHGTLNRFYCINCYEEYSKSYFMTHHLKYCEKCGNVIRPDIVLYGEMLNQKTVFKALDKIQHADTLIVLGSSLVVQPAAGFVSEFKGDNLVIINRDATPYDHTASLVIHDDMTSVIEEIVNSNS
What is the function of this protein?
NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.
What are the official names of this protein?
NAD-dependent protein deacetylase, Regulatory protein SIR2 homolog.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class U subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MLTF_YERPP
Sequence: MTRIKLSYFTIGLVALLLALALWPNIPWRNGQEGQLDQIKARGELRVSTISSPLIYSTEKDTPSGFDYELAKRFADYLGVKLVIIPHHNIDDLFDALDNDDTDLLAAGLIYNRERLNRARTGPAYYSVSQQLVYRLGSPRPKSFSDLKGQVVVASGSAHMTTLKRLKQTKYPELNWSSSVDKSGKELLEQVAEGKLDYTLGDSATIALLQRIHPQLAVAFDVTDEEPVTWYFKQSDDDSLYAAMLDFYSEMVEDGSLARLEEKYLGHVGSFDYVDTKTFLSAIDNVLPSYQHLFEKHAGDIDWKLLAVIAYQESHWNPQATSPTGVRGLMMLTRATADGLGVKDRVDPEESIRGGAIYLQRLMKKLPETIPEDERIWFALAAYNLGYGHMLDARRLTKNQNGNPDSWVDVKMRLPMLSQKRYYPSTTYGYARGHEAYNYVENIRRYQVSLVGYLQEKEKKAAQHAAIEAELGKSNPVVGPGWSIGD
What is the function of this protein?
Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product.  Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus.  Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase F, Murein lyase F.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane.
Protein: PATD2_SOLTU
Sequence: MATTKSFLILIVMILATTSSTFASLEEMVTVLSIDGGGIKGIIPGTILEFLEGQLQKMDNNADARLADYFDVIGGTSTGGLLTSMITTPNENNRPFAAANEIVPFFFEHGPHIFNSSTGQFFGPKYDGKYLMQVLQENLGETRVHQALTEVAISSFDIKTNKPVIFTKSDLAKSPELDAKMYDICYSTAAAPTYFPPHYFTTNTINGDKYEFNLVDGAVATVADPALLSISVATRLAEKDPAFASIRSLNYKKMLLLSLGTGTTSEFDKTYTAEETAKWGAIQWMLVIQRMTDAASSYMTDYYLSTVFQAQNSQKNYLRVQENALTGTTTEMDDASEANMESLVQVGENLLKKPVSKDNPETYEEALKRFAKLLSDRKKLRANKASY
What is the function of this protein?
Probable lipolytic acyl hydrolase (LAH), an activity which is thought to be involved in the response of tubers to pathogens.
What are the official names of this protein?
Patatin group D-2.
What is the protein family that this protein belongs to?
Belongs to the patatin family.
What are the subcellular locations of this protein?
Vacuole.
Protein: SIGA_LISIN
Sequence: MSDKTQNTKPVAELNVEQVKEALIEEGKKKGILTYAKIAARLAPFTLDSDQMDEYLEHVGEAGIEVSDDADDEDPDETELVKEETESFDLTDMSVPPGVKINDPVRMYLKEIGRVDLLTADEEIALAKRIEAGDIEAKGRLAEANLRLVVSIAKRYVGRGMLFLDLIQEGNMGLMKAVEKFDFNKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINKLIRVQRSLLQDLGRDPSPEEIGEEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHLGDFIEDQDATSPSDHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVGRVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  This sigma factor is the primary sigma factor during exponential growth.
What are the official names of this protein?
RNA polymerase sigma factor SigA, Sigma-43.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK1_HUMAN
Sequence: MNGPVDGLCDHSLSEGVFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCGEITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEEDVGAGDQGLMFGYATDETEECMPLTIILAHKLNARMADLRRSGLLPWLRPDSKTQVTVQYMQDNGAVIPVRIHTIVISVQHNEDITLEEMRRALKEQVIRAVVPAKYLDEDTVYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGLCRRVLVQVSYAIGVAEPLSISIFTYGTSQKTERELLDVVHKNFDLRPGVIVRDLDLKKPIYQKTACYGHFGRSEFPWEVPRKLVF
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.  The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
What are the official names of this protein?
S-adenosylmethionine synthase isoform type-1, AdoMet synthase 1, Methionine adenosyltransferase 1, MAT 1, Methionine adenosyltransferase I/III, MAT-I/III.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
Protein: FTHS_CLOBM
Sequence: MFKSDIEIAQESKMKNIKDIAENIGLTEEDIDLYGKYKCKISLDVLKNNKDKKDGKLILVTAINPTPAGEGKSTVTVGLGQALWKKNKKAVIALREPSLGPVFGIKGGAAGGGYSQVVPMEDINLHFTGDMHAITSANNLLAAAIDNHIHQGNILKIDQRRILFKRVMDMNDRALRNVIVALGGKVNGFPREDGFMITVASEIMAILCLAENLMDLKNKMGEILVAYSTEGNPIYCKDLEVQGAMALLMKDAIKPNLVQTLENTPAIIHGGPFANIAHGCNSILGTKMALKLGDYVITEAGFGADLGAEKFFDIKCRKANLKPNCVVIVATVRALKYNSGIPKENLKEQNMEALSKGIKNLGKHIENVNKFGVPAVVAINKFISDTEEEIEFIKKYCKELGAEVSIAEVWEKGGNGGLELADKVLDTIENKESKFNPIYEETLNIKQKIETIAQEIYGAEGVDYSKEAEKQISEIEKLDLDKKPVCMAKTQYSLSDDAKLLGRPCGFRINVKEVRISNGAGFIVVLTGNVMTMPGLPKKPAANNMNVLSDGNIVGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: PGKH2_ARATH
Sequence: MASTAATAALSIIKSTGGAAVTRSSRASFGHIPSTSVSARRLGFSAVVDSRFSVHVASKVHSVRGKGARGVITMAKKSVGDLNSVDLKGKKVFVRADLNVPLDDNQNITDDTRIRAAIPTIKFLIENGAKVILSTHLGRPKGVTPKFSLAPLVPRLSELLGIEVVKADDCIGPEVETLVASLPEGGVLLLENVRFYKEEEKNEPDFAKKLASLADLYVNDAFGTAHRAHASTEGVTKFLKPSVAGFLLQKELDYLVGAVSNPKRPFAAIVGGSKVSSKIGVIESLLEKCDILLLGGGMIFTFYKAQGLSVGSSLVEEDKLELATTLLAKAKARGVSLLLPTDVVIADKFAPDANSKIVPASAIPDGWMGLDIGPDSVKTFNEALDTTQTVIWNGPMGVFEFEKFAKGTEAVANKLAELSKKGVTTIIGGGDSVAAVEKVGVAGVMSHISTGGGASLELLEGKVLPGVVALDEATPVTV
What are the official names of this protein?
Phosphoglycerate kinase 2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HIS4_HAHCH
Sequence: MLIIPAIDLKDGKCVRLKQGRMDDSTVFSDDPVSMAAQWVDAGARRLHLVDLNGAFAGKPVNGEIVSAIAKAYPDLPIQIGGGIRELDIIEQYLDAGVKYVIIGTKAVKEPAFVEEACRAFPGAVIVGIDAKDGMVATEGWAEVSSVSAVDLAKQFRDAGVSSIVYTDIARDGMMQGVNVEATAALARESGLPVIASGGVTNMDDIRRLATVADSGVIGAITGRAIYEGALDLREAQTYCDSIA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTAA_DICDI
Sequence: MGDEEAPSGSIEDRINHKNWKWRVSGLEELTTKFRNSIEGSGPLFNEWGPQFKKILADINPMSQERALEPLSAFIDRCDCVNKFAASYVGVLVEKLFASTRPRAKEKTIECLLLTIEADSAEPVVEALLKGTSSTSPKILLASLAALTQALKTFGPKQIPVKLILKQFSPWFENRDKGIRDQASELFIEIYRWIGKALIPLISEALTPIQLKALQDQFEKLPTDPAVPLKYTRSEAAKALANASKGIQAKPEVVEEIDPYSLMTAVNILPKLTSEFYEGLQAKKWQERSEQMDKLVTILTNTPKIETADFSELCKALKKILADVNVMIVQKAVVSIGLLADSLRGGFTSYVKPFITPILEKFKEKKTSVLQSVHTTMDSLVGKSISLSDIIDELTATMQSKVPQIKQEVLVFICNSITNTKKPADITKVTKQLTKIFMEALNDTDSNIRDNASKAFAALGGIIGERAMTPYLNQIDPIKAKKIKDNMPAVATPVTITPQPLAPVDLKDIDLPVSSSNKKPAAATGNSKSSSTTTPTGRSSNSSPLPPPPSSSDDIKNKLIGAGIVNNEIIEGLGKTQWKDRLQAVDDILENVKGLTADSINGMSESIIQLLCDKPSLKESNFQVLSSIFSIFIQCCKNDSNFTQQRCANSYLTTCIEKLTDVKLKEISSELLFSTGESITPHAVFTSIYQFTSNHKNPKIIADSLVWIQQAIDEFGIGCCSNGIQQLKPLLDYTKQCLESTNPDVKKSAIKLLCTIKINIGATLTDFLGDVKKPTMEVLDREFQKIRDQKPPVPNRQWKGMPPPGSAPVQIEFPRVDISVKLTPAIITNLSDANWKTRSDALDEIERIIIDANRKIQPKLGGLIPALKNRLTDNNQKCTITTLNIIGMLSQAMGGQSFEKHARLLIPGILLLLGDSKKPVRDAVISCMNVIVQSDLGFDVFIGSLAAPMIQESAFTRKESLAWTIVNVTNMKAAPIPSEINTLAKGIISCLQDKSAEIRSLADNLLSILCTQIPLIEFKKELKHVKPASQPSIQTILDKYYQKTGQPIPPPSKTKQSTSSSSSSSSTTSQQSSTPSSPQPIRQQQQQQQQQPTQPQQQQQQQQRRSILQSNNGASNCEFIIFDINGKMNRQKTNQIPSWHFIEPTEEVVEILQDQVLQCFTEEFANLMFSSLPSNSQHMSDLMIGMIEQNPEAIISVLDILFRWITFKLFDTGLASQKRVLKILEILLNKLIDSEYSIGEYEASCLVPILLEKSGSATNEQIKQIFKQSIQQLEELCLPNVLFRFAIEMVTSQNWRTRVEVLNVMASIIDKNGASVCGNLKVVIPLITQNLNDSQSKQSSLLCLNKLYSHIKDECFKYSNISQQDKILIIGNNNNNNNNNNNNNNNNNNNNVQQQQQQQQQQQQQQPRKSLSTDEMSTQLIGCLELLKNYSITKENIEHTVEALKQFSGLMANGKLDDVFVNFAEEYFLVLTSILADTFPQVSKDATILRLCKYLIHTIISILSNKVVAKQCNVRCLEIVLNETIKLYSLAESNSSKQGTESELSKAFNQILLRILQNCNSTILFSTLLQMMSRTDNDQSIQHPGKYNDLLLRCLLRATKSLTTPSILEELNVETVLSEINSFLKSNPSLDEITRKTTKTLTSELYQNRTNQVVKFTKDIISKGQQQKYQYLLNLLIELVPKQFEDLINGNGNGNRISSGGSNNNNNNGGRVSSGGNNNNNSGRENINNININSSLDSPINDHHNSNNTTTTTTRSRTSTGSSNSQQQQLPTTSANTTTTTTTTTTTGKTQSTLSTLKINKEPRDYSGKTDSQKKELLIEIFKKIGNKDLTLDGIHDLYFFIREYPDYDITPNLNSSSQQFQAYITRNLKKIKDSMDAPKDKDDEVVNYQERLKVIQNTFYNQHNQPSSQVVNNNNNNNNNNNNNNNNNINNNNNNNNNSGGNENIAPQLSNTASMASNTLQRLRTLNPDQNSGSNNNNSHQNSPSTSSSNDLNSTVASLRQRLAQLTSKSNE
What is the function of this protein?
Involved in regulation of microtubule dynamics.  Regulates the interaction of microtubules tips with the centrosome and cell cortex.
What are the official names of this protein?
Centrosomal protein 224, CP224.
What is the protein family that this protein belongs to?
Belongs to the TOG/XMAP215 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton. Chromosome, centromere, kinetochore. Note=Associated with the microtubule network. Accumulates at the plus end of microtubules.
Protein: PTH_DEIDV
Sequence: MKLVVGLGNPGTQYAQTRHNVGWLVVNEVARRWGATWRKEKDAEVAEIRLGPAPGVKVLLVKPQTFMNASGKAVVPRLSFFKLDPGALLVVQDDLDSPFGLMKVRLGGRHGGQNGVRDIIRLLGTEAFARLKLGISRPPAGRDPADWVLSRWRDEEQSTLGDLVRLGADAVERWATAGLAEAQQAFNSTDLRPRPEPVPAPQPADVSGPQETGPAERPEV
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IRS4_ASPNC
Sequence: MEPVGVSHNTPEMDPPRNIQTPELPESGSVKDKIGKFSAYQQQPSGLKDAFGKTPTSIGANRSRTPQQIAAQLAAGRSTPGEITATHTGVSRTQGSRPTTSKRSDDNEGPPLLAPKPVWATSANTASVNKLLRSEADLPIRDKSIQRRPVAQISPIEAARLAAKKPRPPPVPRKPAAVATGPTSVPINVHSKGPESPEPTSKNHSSRHLEDTTIPFKAPPALPPRTGASSVPRKDLTNHRRLLDTNHGSRRRPSTPGTASLYTTSLSNSTTSLLDSSSGLDEGALSDAVVASSRASVRASQERKVPPPPPPERRARSRSLKQFPHTAKGEHTDSSSPSTHLRQTLREPTKIAENDEGYQRHKHLIRKHPHKHHEGDRRRWRSEITEKERKRYEGVWAANKGLLLPPAHLRVPEAYPPESSEMVVNLVAADIWSRSRLPRHVLAQVWDLVDGQHIGLLTREEFVVGMWLIDQQLKGHKLPPRVPASVWGSAKRISGVHIHGLPPA
What is the function of this protein?
Positive regulator of phosphatidylinositol 4,5-bisphosphate turnover and negatively regulates signaling through the cell integrity pathway.  Involved in rDNA silencing (By similarity).
What are the official names of this protein?
Increased rDNA silencing protein 4.
What is the protein family that this protein belongs to?
Belongs to the IRS4 family.
Protein: MUTS_VIBC3
Sequence: MMKSNASPSESLSHHTPMMQQYLRLKAENPDILLFYRMGDFYELFYDDAKRASELLDISLTKRGASAGEPIPMAGVPFHAVEGYLAKLVQMGESVAICEQIGDPATSKGPVERKVVRIVTPGTVTDEALLSERVDNLIAAIYHHNGRFGYATMDITSGRFQLSEPQTEEEMAAELQRTSPRELLFPEDFSPVHLMASRQGNRRRPIWEFELDTAKQQLNQQFGTRDLVGFGVEQAKLGLCAAGCLIQYVKDTQRTALPHIRSLTWDRQDQSVILDAATRRNLELTHNLAGGTDNTLAEVLDHCATPMGSRMLKRWIHQPMRDNATLNQRLDAITELKETALYGELHPVLKQIGDIERILARLALRSARPRDLARLRHAMQQLPELHSVMSELKQPHLTELRTHAEPMDELCDLLERAIKENPPVVIRDGGVIADGYSAELDEWRDLANGATEFLERLEAEERDRHGIDTLKVGYNNVHGFYIQVSRGQSHLVPPHYVRRQTLKNAERYIIEELKQHEDKVLNSKSRALALEKQLWEELFDLLMPHLEQLQQLAASVAQLDVLQNLAERAENLEYCRPTLVQEAGIHIQGGRHPVVERVMNEPFIANPIELNPQRRMLIITGPNMGGKSTYMRQTALIALMAHIGSYVPAESASIGPLDRIFTRIGASDDLASGRSTFMVEMTETANILHNATRNSLVLMDEIGRGTSTYDGLSLAWASAEWLAKEIGAMTLFATHYFELTELPNVLPHLANVHLDAVEHGDGIAFMHAVQEGAASKSYGLAVAGLAGVPKPVIKNARAKLQQLELLSSQPAETRKPSRVDIANQLSLIPEPSAVEQALAGVDPDQLTPRQALDMLYQLKKLL
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: HRCA_STRT2
Sequence: MITQRQNAILNLIVEMFTRTHEPVCSKALQDSIDSSSATIRNDMAKLEKMGYLEKAHISSGRMPSRAGFQYFVANSLNLDTIDEQDVYQVVKAFDFEAFKLEDILDAAAKLLAEMTGCTAVIQDVEPTKQRLTGFEIVQLSNHDALAVLTLDESKPVTVQFAIPKNFLSSDLEIFHKLVQGRFLGNTVLDIHYRLRTETPQIVQKYFKITDNVLDLFDYIFSHLFKELIFIEGKVASLAYADLKTYQFLDNPQHVALALRSAISDDEVTKISVAESTEEALENVTVMSHKFLIPYRGTALMHVIGPIEMDYRRMVSLVNVISRVLVMKLTDYYRYLNSNHYEVFLSRNVLKNIERGECLD
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: RL28_LACDB
Sequence: MAKDFVTGKKTTFGNTRSHALNSSSRSWKPNLQKVRILVNGKPKRVWVSTKTLKSGKVTRV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: PLSX_LACLS
Sequence: MKIAIDAMGGDFAPENIVKGVNLAKKELSDVTFQLYGDGAKIRQFLDDETAIEIIETTEVIDFHDDPVAAIKSKKDSSLVRAVTAVKKREADAVLSAGSTGALLTAGLMLVKRIKQVSRPALMSTLPTADGRGFDMLDLGANTENTAHHLVDFAILGSYYAENVRGIEKPRVALISNGSEESKGSPTVKEAHEILSAMTEINFIGNIESRDLLSGGADVVVTDGFTGNAILKAIEGTATVLMKEIKSAIMAGSVTTKIGGVLIKKPLSGLKDLMSTDGAGGAAFVGLKAPVVKAHGNSSELAIASALKQIHKMLESDVSGKLVKHFENMDK
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: KEFC_SHIF8
Sequence: MDSHTLVQALIYLGSAALIVPIAVRLGLGSVLGYLIAGCIIGLWGLRLVTDAESILHFAEIGVVLMLFIIGLELDPQRLWKLRAAVFGGGALQMVICGGLLGLFCMLLGLRWQVAELIGMTLALSSTAIAMQAMNERNLMVTQMGRSAFAVLLFQDIAAILLVAMIPLLAASSASTTMGAFALSALKVAGALVLVVLLGRYVTRPALRFVARSGLREVFSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLFFIGVGMSIDFGTLIENPLRIVILLLGFLIIKIAMLWLIARPLQVPNKQRRWFAVLLGQGSEFAFVVFGAAQMANVLEPEWAKSLTLAVALSMAATPILLVILNRLEQSSTEEAREADEIDEEQPRVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQTNLQLTEMVKEHFPHLQIIARARDVDHYIRLRQAGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRRFNIQMVEEMAMVENDTKARAAVYKRTSAMLSEIITEDREHLSLIQRHGWQGTEEGKHTGNMADEPETKPSS
What is the function of this protein?
Pore-forming subunit of a potassium efflux system that confers protection against electrophiles.  Catalyzes K(+)/H(+) antiport.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system protein KefC, K(+)/H(+) antiporter.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATS1_BOMMO
Sequence: MPCCLWAALSLLLAVVGAGAWTPPRQPLLLTPRHRRHAQETHHLRLLGWDLKLKENKAIRSPYYKECQFFTGRVLHEEGSAVTVTECDGQLYGLLQVGGEEFVLQPTRTQEKHVLRRRDVTHSERSAEYNLTGDTVIDLDLDFDEDDDLLPTSHVHPRHSDHSDKEYFHDMHLFRRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHLLGLTHDGEGNCQSEALRGSVMAPTVLATLHNFAWSSCSKEQFHAKSKKWWCLHERSTDEGVELGGAKELSNYVFTMDEQCRTEFGEGFSVCRSVKVRSACSRLWCAHRAMPHVCRSKRAPPLEGTPCGQNQWCVDRVCEPMPGHSKETKVENKHTPEWGDWEEWSACNADCGYGLRTRTRKCKYRGFVSESACEGAGSQVATCWAGSSCAATRDIRSDLCHRQQSRLIPYLHANESNHCEISCVDYAGGSPTNFGALPDGTPCSYLRPFDVCFQGTCVKGQCNSSDTTCNWCPDGYCNNNTNTYTRLLGNGWTRMTMVPHEARQLSIHIATPIPLHIALRERKRDKPILELSKHSKKFDISSLQDNYLKYDPSVPQNLQIVEMDSNILDLKESFRYEGEAITAGTLLRWNQTDTDIYITSESRLQTDLMIMAIPVNPTLEDAVSVDASVNYSTPTGRTRPLEYRWSIERGPCSASCGGGVRLITAQCHRDQKCPPPRYESCNTHSCEFVWASDDWEECSSTCGSNGVQERQLFCVPSNASMLSRREFIKHSVSPVMCSSSKPPHRQPCNRIPCPVYWREQPWTPCSASCGRGVSRRPLTCPASDELLCGPKPRERRRRCRLRRCPSALRVAVQCPERDHAHYCELFTLEQLHRNCEVPPFRKYCCNACRDADRRQHRRYG
What is the function of this protein?
Involved in larval molting and metamorphosis.  May degrade extracellular matrix (ECM) and basement membrane (BM) during the development of organs to allow degeneration and remodeling of tissues.
What are the official names of this protein?
A disintegrin and metalloproteinase with thrombospondin motifs 1, ADAMTS-1, BmADAMTS-1.
Protein: HUTP_GEOSW
Sequence: MLKQAKGRIGRNAVLLALFEEEEEGKITAHLDNLQWRYCKGKVGSMELQKIVASVETAAKRNNVVNGELYREMHALYHAVVEAVQGVTRGQVELGDLMRTVGLRFAVVRGNPYENSKEGEWIAVALYGTIGAPIRGLEHETIGLGINHI
What is the function of this protein?
Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.
What are the official names of this protein?
Hut operon positive regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the HutP family.
Protein: ADPRM_RAT
Sequence: MADKPDPSSPADGPEPLFSFGVIADIQYADLEDGYNFQRSRRRYYRHSLVHLQGAIEDWNKESSMPCCVLQLGDIIDGYNAQYKVSEKSLELVMNTFQMLKVPVHHTWGNHEFYNFSRDYLANSKLNSKFLEDQIPQHPETTPSENYYAYHFVPFPKFRFILLDSYDLSVLGIDQFSPKYEQCMKILREHNPNVELNSPQGLSEPQYVQFNGGFSQEQLNWLNEVLTFSDANQEKVVIVSHLPIYPEASDSVCLAWNYVDALSIIWSHQCVVCFLAGHTHDGGYSEDPFGVHHVNLEGVIETAPDSQAFGTVHVYPDKMLLKGRGRVPDRIMNYKRE
What is the function of this protein?
Hydrolyzes ADP-ribose, IDP-ribose, CDP-glycerol, CDP-choline and CDP-ethanolamine, but not other non-reducing ADP-sugars or CDP-glucose.  May be involved in immune cell signaling as suggested by the second-messenger role of ADP-ribose, which activates TRPM2 as a mediator of oxidative/nitrosative stress.
What are the official names of this protein?
Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase, ADPRibase-Mn, CDP-choline phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the ADPRibase-Mn family.
Protein: HUTH_ALIF1
Sequence: MYSLEIIPGKLSLKQLREVSRHPTKLSLDPNALPDMLISADVVAQVIEEGKTVYGINTGFGLLANTRIAEKDLETLQRSIVLSHAAGIGEFMDDATVRLMMVLKINSLARGYSGIRPLVIDALIQLVNSEVYPCIPKKGSVGASGDLAPLAHMSTVLLGEGEARYRGEVITGKTALEIAGLTPITLAPKEGLALLNGTQASTAFALEGLFAAEDLYASATVCGAMSVEAALGSRKPFDPRIHRVRGHRSQMDAALAYRHLLAQSSDIGLSHQCCERVQDPYSLRCQPQVMGACLQQIRNSADILEIEANSVSDNPLVFADDGDIISGGNFHAEPVAMAADNLALAISEIGSLSERRMALLIDSGLSKLPPFLVDNGGVNSGFMIAQVTAAALASENKTLAHPASIDSLPTSANQEDHVSMATFAGRRLGDMAENTRGILAVELLAAAQGLDFRAPNKSSNRIEKAKELLRERVDFYDKDRYFAPDIAKANSLLKEAVYNHLMPDTLLPSI
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14_LEUCK
Sequence: MAKKSKIAKAQKREALVAKYADKRAALKAAGDFIGLAALPKDSSPVRMHNRDLIDGRPHAYMREFGMSRLNFRQLAHKGQIPGVRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.