PharMolix/UniProtQA huggingface dataset:
Protein: AGNR1_PAEDI
Sequence: MSAPQKCAAVVVGAGPAGLAVIGNLLERLPGSKIAWIDPYFQAGRVNRRYREVPSNTKVSLFQAYASAVQPFRTVINTTPTPNAFSTMTKLEQDKGCHLHYAADMCRALTEGILKSDEVYRCCGIVTHADLKENLSQWTVRIKSYESLEEVQVVAPRLILCTGSSPTLLRIPVPALSIQRLDLDVVLKPSELVRAIHTGSPQTVAVVGASHSAILALLNLVDLARSSHPQLRIKWFTRNALRYAEYMDGWILRDNTGLKGVAADFAREQLEDDRLPKSEAGRFIEKIDCSDGKETAAYEAHLPSCSHIVQAVGFTRDPLPELARDGMPLKAEFDHESGGFSDQDGRVIKGLYGAGIAFPERVVDPYNNVEYAVGFFKFMKFIKRVCPRWLAA
What is the function of this protein?
Monooxygenase; part of the gene cluster that mediates the biosynthesis of agnestins, dihydroxy-xanthone metabolites (PubMed:30746079).  The pathway begins with the assembly and cyclization of atrochrysone thioester by the non-reducing polyketide synthase Agnpks1 (PubMed:30746079).  The atrochrysone carboxyl ACP thioesterase AgnL7 then breaks the thioester bond and releases the atrochrysone carboxylic acid as the first enzyme-free intermediate (PubMed:30746079).  The decarboxylase AgnL1 then catalyzes the concerted decarboxylation-elimination required to convert atochrysone carboxylic acid into emodin anthrone, which is further oxidized to emodin by the anthrone oxygenase AgnL2 (PubMed:30746079).  Emodin then undergoes reduction catalyzed by the oxidoreductase AgnL4 to yield the dihydroquinone tautomer which is the substrate for reduction by the short chain dehydrogenase AgnL6 reduction to produce hydroxyketone, followed by AgnL8 dehydration and likely spontaneous autoxidation to chrysophanol (PubMed:30746079).  Baeyer-Villiger oxidation by the oxidase AgnL3 leads to monodictyphenone via cleavage of the C-10/C-10a bond of chrysophanol (PubMed:30746079).  Alternative cleavage at the C-4a/C-10 bond of chrysophanol leads also to the formation some cephalone F (PubMed:30746079).  Further conversion to agnestins A and B, requires reduction to dihydro-monodictyphenone, oxidation to agnestin C probably via an epoxide, and rearrangement to either agnestin A or agnestin B directly, although agnestin A or agnestin B can also interconvert (PubMed:30746079).  Within the cluster, AgnR1 is the only unassigned oxidoreductase present which could be involved in this conversion.  However, AgnR1 seems not to be involved in this step, and thus genes involved in the proposed oxidation/reduction may be located elsewhere on the genome (PubMed:30746079).  Further agnestin A derivatives are probably formed by spontaneous decarboxylations, dehydrations and methanolysis reactions (PubMed:30746079).
What are the official names of this protein?
Monooxygenase AgnR1, Agnestins biosynthesis cluster protein R1.
Protein: SK1_EUBSB
Sequence: EQFEDYGHMRF
What is the function of this protein?
Myotropic peptide.
What are the official names of this protein?
Sulfakinin-1, EubSp-SK-1.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RK33_HELAN
Sequence: MAKGKDARIPVLLECTACVRNGVNKESTGISRYITQKNRHNTPNRLELLKFCPYCYKHTIHGEIKK
What are the official names of this protein?
50S ribosomal protein L33, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RPOB_NOVAD
Sequence: MATKATSSRTTGRPGVKKRIRKIFGDIHEVVQMPNLIEVQRESYEQFLRSDPATGYVSGLEKTLRSVFPIQDFAGTASLDIKEKDGYVLESPKYDVNECRQRGITYAAPMKVTLKLATFEVDAETETKSLIDIKEQDVYMGDIPLMTENGTFFINGTERVIVSQMHRSPGVLFDHDRGKTHSSGKYLFAARVIPYRGSWLDFEFDAKDIVNVRIDRKRKLPVTALLHALGLGDEDILHHFYDTVTWARAEGGWKVPFVLEQWRGSKPAFDIVDAKSGEVIFPAGQKISPRAANKAAKDGLEALLIPTEEIFGRYAARDLIDESTGRIWIEAGDEVSPENLDLLDKAGIDNLDLLDIDHISTGPWIRNTLKADKAPDRDHALADIYRVMRPGEPPTRETAEALFDGLFFDGDRYDLSAVGRVKLNMRLGLDCPDTVTTLRTDDILAVVKELVNLKDGKGEVDDIDNLGNRRVRSVGELLENQYRVGLLRMERAVKERMSSVDVSTVMPNDLINAKPAVAAVREFFGSSQLSQFMDQTNPLSEVTHKRRVSALGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGPNIGLINSLSTFARVNKYGFIETPYRKVVDGKVTKDVIYLSAMEEQKHTVAQASAELTADGSFVEELVSARQNGEFVMAPRDTVTLMDVSPKQLVSVAASLIPFLENDDANRALMGSNMQRQAVPLIKADAPFVGTGMEETVARDSGAAISALRSGVVDQVDATRIVIRASGDIEPGQSGVDIYRLQKFERSNQSTCINQRPLVKVGDLIEKGDIIADGPSTEFGELALGRNVLVAFMPWNGYNYEDSILISERIVKEDVFTSIHIEEFEVMARDTKLGPEDITRDIPNVGEEALRNLDEAGIVYIGAEVHPGDILVGKITPKGESPMTPEEKLLRAIFGEKASDVRDTSLRLPPGVAGTIVDVRVFNRHGIEIDDRTRAIQNEEIERLAKDREDERAILNRATFNRLKDMLLGQVAAAAPKGIKKGVEIDEQVLADVERHEWWKFAVADDARQQQLEAVKAQYDTAVKAIQEKFEDRKEKLERGDELAPGVLKMVKVFVAVKRKLQPGDKMAGRHGNKGIISRILPQEDMPFLEDGTPVDFVLNPLGVPSRMNVGQIFETHLGWAARGLGKRIGEALDAWREANPNPEAGQPPEAVRELLKEIYGDNYAAEIDARNDEQIIDFAQSVRLGVPMGSPVFDGAVEKDVTDMLRLAGLDESGQVTLFDGRTGDAFDRKVTVGMKYVLKLHHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALQAYGAAYTLQEMLTVKSDDVVGRTKVYEAIVKGDDTFEAGIPESFNVLVKEMRSLGLNVELSSLDDTDDDDGLAEAAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: GRPE_STAES
Sequence: MSEKDQSVNNTEEDFNVETEDNQNDTNIENSVSNTDNSEANASDSENNSEESIKDEESESQDTKIKELEKLANDNEEKYLRLYAEFENYKRRIQKENQINATYKAQGVLTDILPSIDNIERALQIEGDDESFKSLQKGVQMVHESLLRALKDNGLEEILAEGKEFDPNLHQAVVQDDNPDFKSGEVTQELQKGYKLKDRVLRPSMVKVNQ
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RGCC_RAT
Sequence: MKPPSTQSSPAAVAAAAPAMDSAAAADLTDVLCEFDAVLADFASPFHERHFHYEEHLERMKRRSSASVSDSSGFSDSESADSLYRDSFTFSDEKLNSPTDSTPALLSSAVTPRKAKLGDTKELEDFIADLDRTLASM
What is the function of this protein?
Modulates the activity of cell cycle-specific kinases.  Enhances CDK1 activity.  May contribute to the regulation of the cell cycle.  Fibrogenic factor contributing to the pathogenesis of renal fibrosis through fibroblast activation (By similarity).
What are the official names of this protein?
Regulator of cell cycle RGCC, Response gene to complement 32 protein, RGC-32.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Cytoplasmic in unstimulated cells. Nuclear after activation by complement. Associated with the centrosome during prometaphase and metaphase (By similarity).
Protein: PYRE_YERE8
Sequence: MKAYQREFIEFALNKQVLKFGEFTLKSGRISPYFFNAGLFNTGLELAKLGRFYAAALMDCGVEFDLLFGPAYKGIPIATTTAVALAEHHNRDLPYCFNRKEAKDHGEGGSLVGSPLEGRVMLVDDVITAGTAIRESMEIINAQGATLAGVMISLDRQERGRGEISAIQEVERDYHCKVIAIVTLNDVISYLEEKPEMADHLAAVRHYREQYGV
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: RL33_ALBFT
Sequence: MATKGGREKIKLESTAGTGHFYTTSKNKKTMPEKMLIKKFDPKARKHVDYKEMKLK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RL18_PELPD
Sequence: MARTAQKLITRIKRKVRVRKKIVGTAQRPRLNVFKSARHIYAQLIDDTAGITLASCSTLSTSAESLSYTGNIAAAVHVGKEIAGLAKEKNITAVVFDRNGFLYHGRIKALADAARESGLLF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: GCSPB_CHLL2
Sequence: MIEKLIFDLSREGRKGYSLSGNDIPELSIETVLPAKFLRTEPADLPEVPESEVVRHFIRLSNMNYHVDKNMYPLGSCTMKYNPKVNDAACDLAGFSELHPLQPEKTVQGALQMMYELSGMLAEIAGMSAVTLQPAAGAHGELTGILLIKKYHEARGSKRSKLLVVDSAHGTNPASAAIAGYEIISVSSNADGRTDLGDLKAKLDGEVAALMLTNPNTIGLFEKDILTIAQMVHENGSLLYMDGANMNALLGITRPGDMGFDVVHYNLHKSFSAPHGGGGPGSGPVGVCEKLIPYLPVPVIERIETPEGSSFRLNTDHPESIGRMMNFYGNFSVLIRAYTYIRMLGATGLRRVSENAIINANYLLSRLDSRYDLPYPKPVLHEFCLSGDRQKKAHGVKTLDIAKRLLDYGYHAPTIYFPLIVSEALMIEPTETETRETLDLFAEALLCIADEAENSPDLLRSAPVNTPVKRLDEAQASRQLNICCQG
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 2, Glycine cleavage system P-protein subunit 2, Glycine decarboxylase subunit 2, Glycine dehydrogenase (aminomethyl-transferring) subunit 2.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. C-terminal subunit subfamily.
Protein: TRUB_UREU1
Sequence: MYTINKNIIVINKPINWTSNDVVQKVKRIIKAKKVGHAGTLDPNASGILVLGINEGTKLLTKLTLDSKTYVAEIQFGISTNTYDSTGEIISKINKFITLTEIESAIENLYKNEYWQKPPKFSALKINGKKAYELARNNISFEIEPRLVKIFEYNILDFNYEKQILKIIIKVSKGFYVRSFAVDLAARINNLAHLLSLVRTESGQFSINDAIEIEQVYDYWNNINKHSTN
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: ENV_MPMV
Sequence: MNFNYHFIWSLVILSQISQVQAGFGDPREALAEIQQKHGKPCDCAGGYVSSPPINSLTTVSCSTHTAYSVTNSLKWQCVSTPTTPSNTHIGSCPGECNTISYDSVHASCYNHYQQCNIGNKTYLTATITGDRTPAIGDGNVPTVLGTSHNLITAGCPNGKKGQVVCWNSRPSVHISDGGGPQDKARDIIVNKKFEELHRSLFPELSYHPLALPEARGKEKIDAHTLDLLATVHSLLNASQPSLAEDCWLCLQSGDPVPLALPYNDTLCSNFACLSNHSCPLTPPFLVQPFNFTDSNCLYAHYQNNSFDIDVGLASFTNCSSYYNVSTASKPSNSLCAPNSSVFVCGNNKAYTYLPTNWTGSCVLATLLPDIDIIPGSEPVPIPAIDHFLGKAKRAIQLIPLFVGLGITTAVSTGAAGLGVSITQYTKLSHQLISDVQAISSTIQDLQDQVDSLAEVVLQNRRGLDLLTAEQGGICLALQEKCCFYANKSGIVRDKIKNLQDDLERRRRQLIDNPFWTSFHGFLPYVMPLLGPLLCLLLVLSFGPIIFNKLMTFIKHQIESIQAKPIQVHYHRLEQEDSGGSYLTLT
What is the function of this protein?
The transmembrane protein (TM) acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm (By similarity).
What are the official names of this protein?
Envelope glycoprotein, Env polyprotein.
What are the subcellular locations of this protein?
[Transmembrane protein]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Surface protein]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM. Both proteins are thought to be concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag (By similarity).
Protein: MPAG2_DACGL
Sequence: EAPVTFTVEKGSDEKNLALSIKYNKEGDSMAEVELK
What are the official names of this protein?
Pollen allergen Dac g 2, Allergen Dac g II.
What is the protein family that this protein belongs to?
Belongs to the expansin family. Expansin B subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GSA_DEIGD
Sequence: MTTQIRPFTTQSEALFARAQAVTPGGVNSPVRAFRSVGGTPRFIREAHGAYLTDMDGHRLLDYIGSWGPMILGHDHPAVREAVAAALDRGTSFGAPSEGEVRLAETVTRLTGVDRVRFVNSGTEATMSALRLARGFTGRTFIVKFRGNYHGHADGLLVEAGSGLMTNAAKTLGQAAPSSAGVPEEYARLTLVCEYNDPAALGALMQERGHDVAAVIFEPVVGNAGVLIPTPEFLAALHRVRDAGALLIADEVMTGFRLSLRGATGLLGLTPDLICWGKIIGGGLPVGAYGGRAEVMDFVSPQGPVYQAGTLSGNPLAMAAGLATLEVLESDPSIYARLETYTMQLAEGLRAAAQAAGVPLSVNQIGSMLTAFHQDAPVGSIRTYADAARSDTGAFAVWFQRMLAQGIYWAPSQFESIFVSAAHTDSDLNATLDAAHSAYAQLGGTA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DJC17_MOUSE
Sequence: MAVTKELLQMDLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDNPRAAELFHQLSQALEVLTDAAARAAYDKVRKAKKQAAERTQRLDENRKKVKLDLEARERQAQAHGSEEEEESRSATTLEQEIARLREEGSRQLEEQQRLIQEQIRQDREQRLRGRTENTEGKGTPKLKLKWKCKKEDESQGGYSRDVLLRLLQKYGEVLNLVLSRKKAGNAIVEFATVRAAELAVRNEVGLADNPLKVSWLEGQPQSTVDPGPPGLSKGSVLSERDFESLVMMRMRQAAERQQLIAQMQQEDEGRPT
What is the function of this protein?
May negatively affect PAX8-induced thyroglobulin/TG transcription.
What are the official names of this protein?
DnaJ homolog subfamily C member 17.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly nuclear.
Protein: DUT_SHESM
Sequence: MKTPIELKILDSRIGSEFPLPAYATPGSAGMDLRAMIDTTMTIAPGETQLIPTGIAIHVADPGLAAVILPRSGLGHKHGIVLGNLVGLIDSDYQGPLMVSCWNRSDTPFTLEIGDRLAQLVFVPVVQAQFKLVDEFDSSDRGEGGFGHSGTK
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: CHED_SINMW
Sequence: MNTEAAGKRVHVIQGEFKVVNDPHIVLSTILGSCVAACLRDPVTGVGGMNHFLLPGSASSPSSGADATRYGVHLMELLINGLLKQGARRDRLEAKIFGGARTIARFSNVGEQNAAFARRFLMDEGIRIVGESTGGDHGRKLEYWPSSGRARQYALTGVEAQRAMQMDQRPAAPKPVESSIEFF
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: MAPK3_MOUSE
Sequence: MDGETAGEKGSLVPPPGALGGSALGGAPAPGVRREPKKYAVTDDYQLSKQVLGLGVNGKVLECYHRRSGQKCALKLLYDSPKARQEVDHHWQASGGPHIVRILDVYENMHHGKRCLLIVMECMEGGELFSRIQERGDQAFTEREAAEIMRDIGTAIQFLHSRNIAHRDVKPENLLYTSKEKDAVLKLTDFGFAKETTQNALQTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQYSFPNPEWLDVSEDAKQLIRLLLKTDPTERLTIMQFMNHPWINQSMVVPQTPLYTARVLQEDKDHWDDVKEEMTSALATMRVDYDQVKIKDLKTSNNRLLNKRRKKQAGSSSASQGCNNQ
What is the function of this protein?
Stress-activated serine/threonine-protein kinase involved in cytokines production, endocytosis, cell migration, chromatin remodeling and transcriptional regulation.  Following stress, it is phosphorylated and activated by MAP kinase p38-alpha/MAPK14, leading to phosphorylation of substrates.  Phosphorylates serine in the peptide sequence, Hyd-X-R-X(2)-S, where Hyd is a large hydrophobic residue.  MAPKAPK2 and MAPKAPK3, share the same function and substrate specificity, but MAPKAPK3 kinase activity and level in protein expression are lower compared to MAPKAPK2.  Phosphorylates HSP27/HSPB1, KRT18, KRT20, RCSD1, RPS6KA3, TAB3 and TTP/ZFP36.  Mediates phosphorylation of HSP27/HSPB1 in response to stress, leading to dissociate HSP27/HSPB1 from large small heat-shock protein (sHsps) oligomers and impair their chaperone activities and ability to protect against oxidative stress effectively.  Involved in inflammatory response by regulating tumor necrosis factor (TNF) and IL6 production post-transcriptionally: acts by phosphorylating AU-rich elements (AREs)-binding proteins, such as TTP/ZFP36, leading to regulate the stability and translation of TNF and IL6 mRNAs.  Phosphorylation of TTP/ZFP36, a major post-transcriptional regulator of TNF, promotes its binding to 14-3-3 proteins and reduces its ARE mRNA affinity leading to inhibition of dependent degradation of ARE-containing transcript.  Involved in toll-like receptor signaling pathway (TLR) in dendritic cells: required for acute TLR-induced macropinocytosis by phosphorylating and activating RPS6KA3.  Also acts as a modulator of Polycomb-mediated repression.
What are the official names of this protein?
MAP kinase-activated protein kinase 3, MAPK-activated protein kinase 3, MAPKAP kinase 3, MAPKAP-K3, MAPKAPK-3, MK-3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
[Isoform 1]: Nucleus. Cytoplasm. Note=Predominantly located in the nucleus, when activated it translocates to the cytoplasm. SUBCELLULAR LOCATION: [Isoform 3]: Nucleus. Cytoplasm. Note=Localizes throughout the cell. Degraded in response to osmotic stress.
Protein: RISB1_BRUA2
Sequence: MEFLMSKHEADAPHLLIVEARFYDDLADALLDGAKAALDEAGATYDVVTVPGALEIPATISFALDGADNGGTEYDGFVALGTVIRGETYHFDIVSNESCRALTDLSVEESIAIGNGILTVENEEQAWVHARREDKDKGGFAARAALTMIGLRKKFGA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase 1, DMRL synthase 1, LS 1, Lumazine synthase 1, Type I lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: SECB_BUCAT
Sequence: MLEEKKKQESFEIQRIYIKDVSFEAPNTPNIFHVNWIPTIKLNLNTTTKKIKENIFEVVLMVKVTVKIKEDLVFLCDIDQAGIFFIANINEKRLKHCLYSYCPNILFPYARTCISNLVSCGSFPQMNLAPINFDALYHDHIK
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF05_ARATH
Sequence: MKVSPRLNSALLLLFMILATVMGLVTVEARTCETSSNLFNGPCLSSSNCANVCHNEGFSDGDCRGFRRRCLCTRPC
What is the function of this protein?
Confers broad-spectrum resistance to pathogens.
What are the official names of this protein?
Defensin-like protein 5, Low-molecular-weight cysteine-rich protein 66, Protein LCR66, Plant defensin 2.4.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: MURC_PSYIN
Sequence: MIKIDLAQIRTTVPEMRRVKQIHFVGIGGAGMGGIAEVLAYEGYKISGSDIAENPVVRRLRSLGAEIFIGHQQDNIYGASVVVVSTAINADNPELLAAQQARIPVVRRAEMLAELMRYRHGVAVSGTHGKTTTTSLIASIYGQAQLDPTFVIGGLLNSAGTNAKLGQSRYLIAEADESDASFLHLQPMVSVVTNIEADHMDTYEGNFEVLKDTFVRFIQNLPFYGTAVVCLDDAVIEQLIPRFARQTVTYGFHEQADVRISDFSQCVNRSEFSVHRINKPAMKIQLNLPGKHNALNAAAAIAVAMEDDIDDFSISKALNEFAGIGRRFEQYGEFETGRGKAILVDDYGHHPTEVQATIDAARAAWPDKRLVMAYQPHRYTRTRDLYEDFAHVLAQVDQLLLLDVYAAGETPIAGADSRSLCRTIRQRSGKEPIFVASPEVLPAMLAQIIDDGDLVLTQGAGNIGAVVKTLAELQLNIEKMKKASRVQ
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR16_PHATC
Sequence: MLKLRLKRTGRKRSPSYRLVVMENTARRDGRPIEELGYYSPITKQYKFDVEKIKKWLDFGVKPTETVSSLLRKAEIIS
What are the official names of this protein?
30S ribosomal protein S16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PLSY_ECOLU
Sequence: MSAIAPGMILIAYLCGSISSAILVCRLCGLPDPRTSGSGNPGATNVLRIGGKGAAVAVLIFDVLKGMLPVWGAYELGVSPFWLGLIAIAACLGHIWPVFFGFKGGKGVATAFGAIAPIGWDLTGVMAGTWLLTVLLSGYSSLGAIVSALIAPFYVWWFKPQFTFPVSMLSCLILLRHHDNIQRLWRRQETKIWTKFKRKREKDPE
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-ACP to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme can also utilize acyl-CoA as fatty acyl donor, but not acyl-PO(4).
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS2_CORU7
Sequence: MAVVTMRELLDAGVHFGHQTRRWNPKMRRFIFTDRNGIYIIDLQQTLTYIDEAYEFVKETVAHGGNILFVGTKKQAQEAVANEAERVGMPYVNHRWLGGMLTNFQTVSKRLARMKELQAMDAAEDGYQGRTKKEILLLNREREKLERVLGGIADMTKVPSAMWVVDTNKEHIAVSEAKKLGIPVVAILDTNCDPDEVQYPVPGNDDAIRSANLLTSIISSAVEEGRKARAERQAAAAKDAAGDTGKSEADAEAVKAEAAAEEKAETTEA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: ADF6_ARATH
Sequence: MSFRGLSRPNAISGMGVADESKTTFLELQRKKTHRYVVFKIDESKKEVVVEKTGNPTESYDDFLASLPDNDCRYAVYDFDFVTSENCQKSKIFFFAWSPSTSGIRAKVLYSTSKDQLSRELQGIHYEIQATDPTEVDLEVLRERAN
What is the function of this protein?
Actin-depolymerizing protein.  Severs actin filaments (F-actin) and binds to actin monomers.
What are the official names of this protein?
Actin-depolymerizing factor 6, ADF-6, AtADF6.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RIBA_ACIBS
Sequence: MPIEFIATSKLPTAFGEFNISVFQDPVTGEEHVALSKGLENPPTDPVLVRVHSECLTGDAFASLKCDCGPQLQATQKLINEAGQGVILYLRQEGRGIGLTNKIRAYALQDQGHDTVDANLLLNLPADARRYDMCSIMLDHLKVKEVKLITNNPLKIQALKDQGINVVDRVPLTVGRNPFNEQYLKTKRERMAHLYQKDDF
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.