PharMolix/UniProtQA huggingface dataset:
Protein: BOP1_LEIIN
Sequence: MTSPKGKPSPKRSAPAPTTAALTPRTEERTEGATSSASASASSHISSSFDSPRDDTVVFTGYTAESKHNAHGYERLHDIILQDGDTGADSEDGRANEDNVILFPHAEELANAAAGINGDDDNGRVVRLGTIQHLEESDSSEDEPTLNRVGDIPLEWYKDEDHIGYDIEGKKLMKKERSALERLLEATDDPNAMRTIYDALHDEKKTLSNADLQLIFNLQRNRTTNPNYDMYSEVQEDTVVFDPLNHPLARSGGPSKRAFVPALHDMKVIAKMVRRLRKEEAERKLRPGKEEKEEEDQLLWDDGHVEMDTHTHFKYFNRVPKPKLPPPGTFESYRPPPEYLPSERAKQRQARLRAIDRKEHFLPQSFDALRHVPFYHHTIQDRYQRCLDLAFFPRAQRTRLVVDPDKLLPELPDPKDLRPYPEKLSFHYKGHTATVRSVSVSPNGQYLATGCDDHLVRVFEVQTGRLMKRYDMGAPVQQVEFCPSTSLNILAAAVEYSLVFIVPTFAAHTLVNDHTIRFLRAPGLSAGQREAAHALGAVDTLGGRAVTQTTLDADETAHEATADLHDIEEREKRAEFVDASAKERNAGIVVKIAMHAKVKKFCFHIKGDYLCALCPKDHVKYRQTIMLQLSKRKVFCPFRKFSEVVTDCRFHPREPIFFLATTNSVRCYNLMAHRLQRRFKASGGVTTCLSIHPEGDNFLVGDTTSHTSWFDMDFSDKPYKRMRSHRGVVNALAFHPKTNAYPLFATGASDGQVHVFHGMVYDDYNKNALVVPVKILKHQRPVYAVAWHPTLAWLFTSTEDGVVTAWTE
What is the function of this protein?
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
What are the official names of this protein?
Ribosome biogenesis protein BOP1 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat BOP1/ERB1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: SPO1_YEAST
Sequence: MQKLLFVFSVLLTVVLATAPFQVQCPSSPLIREAKHELCPEETLYLKKKKIKTKNKLIQFLKSLTEAKFSSKFYKRVLKDPPKIGIAISGGGYRSMLVGTGFISQMNDYGLFEYSDYIAGLSGGSWILMDLVVQNFEVKSLLQEWDLEEDLLLGIPEFDISEEEIVTNAKKEYNDNDLKMKKRQGGSLITSSSNFYEQIEEIMNSIEEIPEDYMITKRNLNPLARLKKIFFPNNTFTGTDAKIETFKKVLDFYKSLHLKIKPKKMEGFQISFTDYWGKAIVQRLKKNFDDDPNHSFSFSKLVNSSKKFKECSVPIPIFVANCKNGLLSNVIFEFTPFEFGSWENILRLFVKLPYLGSKIVSGKAEKCINNFDDLGFITATSSSIFNNVLIFIWNLASQSSREAMKALNMVMGIFGLGKEEIFSISKDSSRLETDYAVYQPNPFYLYPEKDNVLTNKNHLYLVDGGEDGENIPLRTLVIPERELDVIFVLDSSSDIDNYPNGSKLKRIFEKLDEENVHYQFPNNVKTFTHPIVIGCNATKRTGHDSFLPIIIYHANANHGNASNTSTFKITYNQSEVSSMLPTGRGVFSNDYDLYYKNCLGCILTKRTMDRLPRKKKFSPFCLQCFKDYCYS
What is the function of this protein?
Regulates spindle pole duplication in meiosis I, but not in mitosis.  Required for meiosis I, meiosis II chromosome segregation and spore formation.  Binds phosphatidylinositol (4)P mono- and polyphosphates.
What are the official names of this protein?
Putative meiotic phospholipase SPO1, Sporulation-specific protein 1.
What is the protein family that this protein belongs to?
Belongs to the lysophospholipase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein.
Protein: GATC_CLOB1
Sequence: MSVSKKDVEYVAELARLEFKEEEKDSFVNDLNKILNYMEKLDELNTDDVDIVVNPYYIENKYREDNVEKSMELKEVIDNAPESLEEYVIVPKVID
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: FEN1_BABBO
Sequence: MGIKGLIGFLSDAAPGCISEVTLESLSGTSIAIDASTALYQFTIAIREGSYLSSLTNSKGESTSHIAGLLNRCIRLLELGIRPVFVFDSTPPEAKSQTLAKRKLLREEAESSLEKAIEEDDKEAIRKYVGRTVRITQKENESAKKLLRLVGVPVIEAAEEAEAQCAYLCQRGFVTAVGSEDADALVFRCGVLLKNLTASNKPVVRVDLAKALELLELTHEQFTDFCILCGCDYCGTLKGVGPKTAYNLIKKHGSISRILEVRSETLEGYEAAQEYFRDPKVRDITTIDRCEANIDGLREFLISENDFSEERVDKLIERLQKARSKKTQLSLKSFFGYPPRAANITRNYTVPIKGVSPPAVVESAVDSTSDDGKDEVPSDDKVPSVNEVPTVDKVPSVNEVPTVEEAPPADAVPTVEDTSEPPSEEPDAKKRNKRVPIEVDDSLVPDNLKRFICVQHYDPRVTIKRTGASELGSDSVDSLVSHICGVYGIQSGTPDNDLSVVGEGILWPNPILQRFRSVTKDLPNSRLHELWRCSSSHGISWDALDKLYINFREARDSSVEEWDKYAPEIVDFASKVARDKITQWLDGSTSCPPRLLRRWTHLLYSRWRERYLHVYGPRMLSRYLKGEVTDRVLVREINECLPAGVECSELPLDTEPSEHNPHFVRRVPKSGS
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: DAPE_BUCAT
Sequence: MTCSITELAKKLISIPSVSPKDLGCQDIIIKRLCAIGFDIKRVNVNDTKNFWAFRGTGKTLTFAGHTDVVPIGQDKDWQTDPFQPVIRSGYLFGRGSADMKGALAAMITAAERFVNKFPNHKGRLSFLITSDEESSAVDGTIKVVEYLMSKRDMIDYCIVGEPSSTNIVGDVIKNGRRGSITANITIHGIQGHIAYPDLADNPIHKGLPVILKILSIKLDSGNDFFLPSSINIANIHAGNGFNNVIPGSLFVQFNIRFSSEVSEKHIQSQIVNILNSNDINYSIEWLFSGKPFITKKGLLIDTVIQSIFYFNKKKPILSTSGGTSDGRFIALMGSEVVELGLVNNTIHKVNECVKISDLKLLSCMYEDIMKNLLS
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: DMRTA_HUMAN
Sequence: MERSQCGSRDRGVSGRPHLAPGLVVAAPPPPSPALPVPSGMQVPPAFLRPPSLFLRAAAAAAAAAAATSGSGGCPPAPGLESGVGAVGCGYPRTPKCARCRNHGVVSALKGHKRFCRWRDCACAKCTLIAERQRVMAAQVALRRQQAQEESEARGLQRLLCSGLSWPPGGRASGGGGRAENPQSTGGPAAGAALGLGALRQASGSATPAFEVFQQDYPEEKQEQKESKCESCQNGQEELISKSHQLYLGSSSRSNGVIGKQSIGSSISEYSNKPDSILSPHPGEQSGGEESPRSLSSSDLESGNESEWVKDLTATKASLPTVSSRPRDPLDILTKIFPNYRRSRLEGILRFCKGDVVQAIEQVLNGKEHKPDNRNLANSEELENTAFQRASSFSLAGIGFGTLGNKSAFSPLQTTSASYGGDSSLYGVNPRVGISPLRLAYSSAGRGLSGFMSPYLTPGLVPTLPFRPALDYAFSGMIRDSSYLSSKDSITCGRLYFRPNQDNP
What are the official names of this protein?
Doublesex- and mab-3-related transcription factor A1.
What is the protein family that this protein belongs to?
Belongs to the DMRT family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ULAF_SALCH
Sequence: MQKLKQQVFDANMDLPRYGLVTFTWGNVSAIDRERGLVVIKPSGVAYETMKVDDMVVVDMDGKVVEGGYRPSSDTATHLALYQRYPSLGGVVHTHSTHATAWAQAGMAIPALGTTHADYFFGDIPCTRALSEEEVQGEYELNTGKVIIETLGEVEPLHTPGIVVYQHGPFAWGKDAHDAVHNAVVMEEVAKMAWIARGINPALNPIDDYLMNKHFMRKHGPNAYYGQK
What is the function of this protein?
Catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate.  Is involved in the anaerobic L-ascorbate utilization.
What are the official names of this protein?
L-ribulose-5-phosphate 4-epimerase UlaF, L-ascorbate utilization protein F, Phosphoribulose isomerase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. AraD/FucA subfamily.
Protein: UREG_BORPA
Sequence: MHDISSLTTRTKTLPPLRVGVGGPVGSGKTTLLEMVCKAMYPQFDLIAITNDIYTKEDQRLLTLSGALPPERILGVETGGCPHTAIREDASINLIAIDQMLEQFPDADIVFVESGGDNLAATFSPELSDLTLYIIDVASGEKIPRKGGPGITKSDLFIINKTDLAPYVGADLAVMEADTRRMRGDKPFVMCNLKTGDGLDQVIAFLKTEGLFRG
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GXM2_ARATH
Sequence: MRNKSQSFISSKLIFICCSILVLFILFLKRASFSSNSTATIRDEYHQKSKCPSTPQQCTKLPTSLSDALVHYVTSEITPQQTFDEVSVSKRVLDKKSPCNFLVFGLGHDSLMWASLNHGGRTLFLEEDEAWIETVTKKFPNLESYHVVYDTKVKDSNKLMELKRTEDCKAVSDPRDSKCALSLKGFPADVYETQWDVIMVDAPTGYHDEAPGRMSAIYTAGLLARNRYDGGETDVFVHDINRPVEDEFSVAFLCGGYMKEQQGRLRHFNIPSHRASFGTPFCPADISRRF
What is the function of this protein?
Methyltransferase catalyzing 4-O-methylation of glucuronic acid side chains on xylan.
What are the official names of this protein?
Glucuronoxylan 4-O-methyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass membrane protein.
Protein: EX7S_PECAS
Sequence: MPKKTEQPVSFESSLNELEKIVTRLESGELPLDDALNEFEHGIQLARQGQQKLQQAEQRVQILLSDDPDAPLSPFTPDNDTL
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAD8B_ORYSJ
Sequence: MSRHFRTHTTSRLTFPSSSGGLAITRLPFSSTSSKLLLQQLSSTSPAAAATAVTITTSSPARNLQRARASAAEQGMEEHGKAAVGWAARDDSGVLSPYNFSRRAQKDDDVTIKVLYCGICHTDLHVVKNDWGNAMYPVVPGHEIVGVVTGVGAGVTKFKAGDTVGVGFFVGSCRTCDSCGKGYENYCPTMVITSNGKDYGGAATQGGFSDAIVVNEHYVLRVPAGLPLDGAAPLLCAGVTVYSPMVIHGLNAPGKHVGVVGLGGLGHVAVKFAKAFGMRVTVISTSPGKRREALEHLGADEFLVSRDAGQMAAAAGTMDGILNTVSAWHPVAPLFALMKPMAQMVFVGAPTRPLELPAYAIVPGGKGITGNCVGGIRDCQAMLDFAGEHGITAEVEVIKMDYVNTAMERLEKNDVRYRFVIDVAGSSLGGSGDDKI
What is the function of this protein?
Involved in lignin biosynthesis.  Catalyzes the final step specific for the production of lignin monomers.  Catalyzes the NADPH-dependent reduction of coniferaldehyde, 5-hydroxyconiferaldehyde, sinapaldehyde, 4-coumaraldehyde and caffeyl aldehyde to their respective alcohols.
What are the official names of this protein?
Probable cinnamyl alcohol dehydrogenase 8B, OsCAD8B.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: MDH_CERS4
Sequence: MARPKIALIGAGQIGGTLAHLAAIKELGDVVLFDIAEGTPQGKALDIAQSGPSEGFDAVMKGANSYEEIAGADVCIVTAGVPRKPGMSRDDLIGINLKVMKSVGEGIKAHAPNAFVICITNPLDAMVWALQQFSGLPAEKVVGMAGVLDSARFRHFLSVEFNVSMRDVTAFVLGGHGDTMVPLVRYSTVAGIPLPDLVQMGWTTQEKLDQIVQRTRDGGAEIVGLLKTGSAFYAPATSAIEMAEAYLKDQKRLLPCAAYVDGAFGLNGMYVGVPTIIGAGGIEKIVDIKLNDDEQAMFDKSVNAVKGLVEACKGIDSSLA
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: MURD_COXBU
Sequence: MSSESLTVIVGLGKTGLSCAQFLAAKNQPFAVMDSREEPPEWENFIKTYPRVELIRGQFSEKLLNEAQEIILSPGVSLQEPLIAKQAAQGKSIIGDIELFARNVNKPIIAITGSNGKTTVTTVVGLMMKAAGRNVSVCGNIGEPVLEQITPEPDYYVLELSSFQLETTFSLRSQAATILNISEDHMNRYATLQDYLRAKQRIYTDCFIPIVNADEPEIWRHLPFNKKPLSFGLNNAADFSLAEHNQKTSIAYQGKILMPIQELKLNARHHLQNALAALALGTAAKIPIENMLHVLRDFSGIRHRCQWVRKYKEIDYYNDSKGTNVGATRAAIESLGQAAKGQLILIAGGQGKGADFSPLKDVVKRYVKQVILIGEDAPLLEKTLKEITVIKHADSMNEAVKRSTQAAKAGDIVLLSPACASFDMFTNYEHRGDVFTETVEAL
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2B1_CANGA
Sequence: MSAEKKPASKAPAEKKPAAKKTAPSADGKKRTKARKETYSSYIYKVLKQTHPDTGISQKSMSILNSFVNDIFERIASEASKLAAYNKKSTISAREIQTAVRLILPGELAKHAVSEGTRAVTKYSSSTQA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.1.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: PEX3_MACFA
Sequence: MLRSVWNFLKRHKKKCIFLGTVLGGVYILGKYGQKKIREIQEREAAEYIAQARRQYHFESNQRTCNMTVLSMLPTLREALMQQLNSESLTALLKNRPSNKLEIWEDLKIISFTRSIVAVYSTCMLVVLLRVQLNIIGGYIYLDNAAVGKNGTTILAPPDVQQQYLSSIQHLLGDGLTELITVIKQAVQKILGSVSLKHSLSLLDLEQKLKEIRNLVEQHKSSSWINKDGSKSLLCHYMMPDEETPLAVQACGLSPRDITTIKLLNETRDMLESPDFSTVLNTCLNRGFSRLLDNMAEFFRPTEQDLQHGNSMNSLSSVSLPLAKIIPIVNGQIHSVCSETPSHFVQDLLTMEQVKDFAANVYEAFSTPQQLEK
What is the function of this protein?
Involved in peroxisome biosynthesis and integrity.  Assembles membrane vesicles before the matrix proteins are translocated.  As a docking factor for PEX19, is necessary for the import of peroxisomal membrane proteins in the peroxisomes (By similarity).
What are the official names of this protein?
Peroxisomal biogenesis factor 3, Peroxin-3, Peroxisomal assembly protein PEX3.
What is the protein family that this protein belongs to?
Belongs to the peroxin-3 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Multi-pass membrane protein.
Protein: ISPF_NATTJ
Sequence: MRIGHGVDVHKLVKGEDLVLGGVQIPSDLGLKGHSDADVLIHAIMDAMLGSLALGDIGKHFPDDDPRYHQIDSKVLLKKTYQLITSYGYQLINLDSTIMAEKPKLAPYIDEMRITISDVLDLYPSQIGIKATTFEKLGFVGSGQGIMAQAVVLMERLY
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: ATPB_STAA2
Sequence: MGIGRVTQVMGPVIDVRFEHNEVPKINNALVIDVPKEEGTIQLTLEVALQLGDDVVRTIAMDSTDGVQRGMDVKDTGKEISVPVGDETLGRVFNVLGETIDLKEEISDSVRRDPIHRQAPAFDELSTEVQILETGIKVVDLLAPYIKGGKIGLFGGAGVGKTVLIQELINNIAQEHGGISVFAGVGERTREGNDLYFEMSDSGVIKKTAMVFGQMNEPPGARMRVALSGLTMAEYFRDEQGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTTKGSVTSIQAVFVPADDYTDPAPATAFAHLDATTNLERKLTEMGIYPAVDPLASTSRALEPSIVGQEHYEVARDVQSTLQKYRELQDIIAILGMDELSDEDKQTVERARRIQFFLSQNFHVAEQFTGQKGSYVPVKTTVANFKDILDGKYDHIPEDAFRLVGSMDDVIAKAKDMGVEV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MKTX2_MESMA
Sequence: MNYLIVISFALLLMTSVESGRDAYIADSENCTYFCGSNPYCNDLCTENGAKSGYCQWAGRYGNACWCIDLPDKVPIRIPGPCRGR
What is the function of this protein?
This protein markedly relaxes the rat carbachol-precontracted anococcygeus muscle.  This relaxation is inhibited by the inhibitor of nitric oxide (NO) synthase, N-nitro-L-arginine methyl ester (L-NAME), suggesting that the response induced by this protein is NO-mediated (By similarity).
What are the official names of this protein?
Makatoxin-2, Makatoxin II, MKTXII, MakatxII, MkTx II.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HSTC_CHLRE
Sequence: MDLCSSTGRGACLSPASTSRPCPAPVHLRGRRLAFSPAQPAGRRHLPVLSSAAVPAPLPNGGNDESFAQKLANFPNAFWKFLRPHTIRGTILGTTAVTAKVLMENPGCIDWALLPKALLGLVALLCGNGYIVGINQIYDVDIDVVNKPFLPVASGELSPALAWGLCLSLAAAGAGIVAANFGNLITSLYTFGLFLGTVYSVPPLRLKQYAVPAFMIIATVRGFLLNFGVYSATRAALGLPFEWSPAVSFITVFVTLFATVIAITKDLPDVEGDQANNISTFATRMGVRNVALLAIGLLMANYLGAIALALTYSTAFNVPLMAGAHAILAATLALRTLKLHAASYSREAVASFYRWIWNLFYAEYALLPFL
What is the function of this protein?
Involved in the synthesis of plastoquinone-9.  Can use both homogentisic acid and 2,5-dihydroxyphenylacetic acid gamma-lactone as prenyl acceptors, and solanesyl diphosphate > farnesyl diphosphate > geranylgeranyl diphosphate >> phytyl diphosphate as prenyl donors.  Do not catalyze the decardoxylation of homogentisate uncoupled from prenylation.
What are the official names of this protein?
Homogentisate solanesyltransferase, chloroplastic, CrHST, Homogentisate prenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: TRUD_ECOHS
Sequence: MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHILVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDLSAFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLNDICVKGVPNYFGAQRFGIGGSNLQGAQRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQVVDGDALQLAGRGSWFVATTEELAELQRRVNDKELMITAALPGSGEWGTQREALAFEQAAVAAETELQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVVRELINTTGDYAHIAE
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: RS2_BURO1
Sequence: MAVTMRQMLEAGVHFGHQTRFWNPKMAPFIFGHRNKIHIINLEKTLPMFTDAQKYVRQLAANRGTILFVGTKRQSRDTIAQEAQRAGMPYVNARWLGGMMTNFKTLKVSIKRLKDMEAAVESGETEKMSKKEALLFEREIAKLQKSIGGVKDMGGIPDAIFVVDVGYHKIAVTEANKLGVPVIAVVDTNHSPEGVDYVIPGNDDSSKAVALYAEGVADAILEGRANAVNEVVQAARGDDEYVEENA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: COBT_SHEPC
Sequence: MSQSAVSFQINSVSKVQEQLIQQKINLKTKPLGALGQLESLALQIARIQGADQPYIANPTMLVFAGDHGIAAEGVSIAPSEVTRQMVQNFAHGGAAINVFCRQVGFKLEVIDCGILTPIEGVKGIIDQRLGAGTGAIHLEPAMALETVDKGFAMARDLIERHHQAGCNLVAFGEMGIGNTSAASAIMAAIMQLDVIDCVGRGTGINQETLARKLMLIELALLLHQSALTGPKEVLACLGGFEIVQMTGAMLAAAERNMLVVVDGFIATAAALVAVTIAPNVRDYLIFAHQSDEQGHLRMLEFLQAKPLLSLGLRLGEGTGAALALPLIQAAVNFYNQMASFSDAGIEAVV
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: RL31_DESAP
Sequence: MKEKLHPAYQKARIVCVCGAQFEVGSTKKEMRVDICSKCHPFYTGMQRTVETRGRADKFRRKYGLGK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: ARGC_XANAC
Sequence: MTVQPKTIGIVGARGHTGSELIKLVAAHPQLHLSFVSSRELAGQRVAEHNDAYQGQLRYENLDADAVAVKAADVVILALPNGKAAPFVAAIDAATPQTLVIDLSADYRFDPAWYYGLPELTRGSYAGQRRISNPGCYATAMQLTIAPLLDQLAGPPQCFGVSGYSGAGTTPSDKNNPELLSNNLMPYALTNHMHEREVSAQLGVPVEFMPHVAPHFRGITMTVNLWLQQPLTREQIQARYTQRYADEPLIEIVDEAPWVSRIAGKHGVQIGGVTLAPGNKRVVVVATLDNLLKGAATQAMQNLNLALGWDELMAIR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADE_LIMRD
Sequence: MRKYQEEIINALGVNSQIDPQAEVTKRVQFICDFLQTTKMKALVLGISGGQDSSLAGRLSQLAVEKLREETGDNEYQFIAVRLPYGEQADESDAMFAINDFIKPDKIMRVNIKAATDAMVASLNEAGTPISDFSKGNIKARERMIVQYAIGGENKGAVVGTDHAAEAVTGFYTKFGDGGADITPLSGLDKRQGKALLQYLGAPAKLYDKTPTADLEEDKPMRPDEEALGVRYDEIDDYLEGREVSPAAAEKIESWYRRTQHKRHLPIAPYDTWWK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: NKG2A_PANTR
Sequence: MDNQGVIYSDLNLPPNPKRQQRKPKGNKSSILATEQEITYAELNLQKASQDFQENDKTYHCKDLPSAPEKLIVGILGIICLILMASVVTIVVIPSTLIQRHNNSSLNTRTQKARHCGHCPEEWITYSNSCYYIGKERRTWEESLLACTSKNSGLLSIDNEEEMKFLSIISPSSWIGVFRNSSHHPWVTINGLAFKHEIKDSDNAELNCAVLQVNGLKSAQCGSSIIYHCKHKL
What is the function of this protein?
Immune inhibitory receptor involved in self-nonself discrimination.  In complex with KLRD1 on cytotoxic and regulatory lymphocyte subsets, recognizes non-classical major histocompatibility (MHC) class Ib molecule MHC-E loaded with self-peptides derived from the signal sequence of classical MHC class Ia molecules.  Enables cytotoxic cells to monitor the expression of MHC class I molecules in healthy cells and to tolerate self.  Upon MHC-E-peptide binding, transmits intracellular signals through two immunoreceptor tyrosine-based inhibition motifs (ITIMs) by recruiting INPP5D/SHP-1 and INPPL1/SHP-2 tyrosine phosphatases to ITIMs, and ultimately opposing signals transmitted by activating receptors through dephosphorylation of proximal signaling molecules.  Key inhibitory receptor on natural killer (NK) cells that regulates their activation and effector functions.  Dominantly counteracts T cell receptor signaling on a subset of memory/effector CD8-positive T cells as part of an antigen-driven response to avoid autoimmunity.  On intraepithelial CD8-positive gamma-delta regulatory T cells triggers TGFB1 secretion, which in turn limits the cytotoxic programming of intraepithelial CD8-positive alpha-beta T cells, distinguishing harmless from pathogenic antigens.  In MHC-E-rich tumor microenvironment, acts as an immune inhibitory checkpoint and may contribute to progressive loss of effector functions of NK cells and tumor-specific T cells, a state known as cell exhaustion.
What are the official names of this protein?
NKG2-A/NKG2-B type II integral membrane protein, CD159 antigen-like family member A, NK cell receptor A, NKG2-A/B-activating NK receptor.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.