PharMolix/UniProtQA huggingface dataset:
Protein: CDSA_AQUAE
Sequence: MRITQGERESSGEFLMSREFYGVLIGVTTLLVIFLPKSLFLLVILFLCFAISREVSVALGENEVFYFSPLVLLTYYFADPLVFPLIGLLSLYFAYKRWELNSFFKSTFLLFYPALFLVYLIKIKEISTYYLLIFIFGIWINDVFAYYIGKNFGKTPLFPKISPKKTVEGFLGGVLFGSLFFALTLPYGILNSFLLGTFVLTVGVAGDYFKSFIKRQVGIKDFSNVFGEHGGFTDRFDALVFSAPVFYLIMCAGELNCKL
What are the official names of this protein?
Phosphatidate cytidylyltransferase, CDP-DAG synthase, CDP-DG synthase, CDP-diacylglycerol synthase, CDS, CDP-diglyceride pyrophosphorylase, CDP-diglyceride synthase, CTP:phosphatidate cytidylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CDS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NTPP_GLOC7
Sequence: MTIPFILASASPARRKLLQTMGIDPIVRHSNFDESQIQLTDTIALVQTLAQCKAEVVANEVNEGLILGCDSLLEVDTQSYGKPESPEEAIIRWQKMRGNSGVLYTGHALIDKTQNKQLLRCGITQVYFADVSDAEIKAYVASGEPLKCAGCFALEGKGGLFVEKLEGCHSNVIGLSLPLLREMLNELGYTVMDFWQ
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y039_MYCBO
Sequence: MVAPHEDPEDHVAPAAQRVRAGTLLLANTDLLEPTFRRSVIYIVEHNDGGTLGVVLNRPSETAVYNVLPQWAKLAAKPKTMFIGGPVKRDAALCLAVLRVGADPEGVPGLRHVAGRLVMVDLDADPEVLAAAVEGVRIYAGYSGWTIGQLEGEIERDDWIVLSALPSDVLVGPRADLWGQVLRRQPLPLSLLATHPIDLSRN
What are the official names of this protein?
UPF0301 protein Mb0039.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: SODC_DANRE
Sequence: MVNKAVCVLKGTGEVTGTVYFNQEGEKKPVKVTGEITGLTPGKHGFHVHAFGDNTNGCISAGPHFNPHDKTHGGPTDSVRHVGDLGNVTADASGVAKIEIEDAMLTLSGQHSIIGRTMVIHEKEDDLGKGGNEESLKTGNAGGRLACGVIGITQ
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn].
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: LYSX_THET8
Sequence: MLAILYDRIRPDERMLFERAEALGLPYKKVYVPALPMVLGERPKELEGVTVALERCVSQSRGLAAARYLTALGIPVVNRPEVIEACGDKWATSVALAKAGLPQPKTALATDREEALRLMEAFGYPVVLKPVIGSWGRLLAKVTDRAAAEALLEHKEVLGGFQHQLFYIQEYVEKPGRDIRVFVVGERAIAAIYRRSAHWITNTARGGQAENCPLTEEVARLSVKAAEAVGGGVVAVDLFESERGLLVNEVNHTMEFKNSVHTTGVDIPGEILKYAWSLAS
What is the function of this protein?
Catalyzes the ATP-dependent formation of a covalent bond between the amino group of alpha-aminoadipate (AAA) and the gamma-carboxyl group of the C-terminal glutamate residue in LysW.
What are the official names of this protein?
Alpha-aminoadipate--LysW ligase LysX, AAA--LysW ligase LysX.
What is the protein family that this protein belongs to?
Belongs to the RimK family. LysX subfamily.
Protein: MINE_METC4
Sequence: MSVLTFLKPRGSGSVARERLQLILAHERVENGRPDLIITLREEILNVIAKHVTVERDKVQIKLERGEGVSTLGVDIEFPVDAVIKPKAKAKRAIA
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: PETN_RIPO1
Sequence: MDILALGWVSVLALFTWSIAMVVWGRNGF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 8, Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PetN family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: HLDD_VIBVU
Sequence: MIIVTGGAGMIGSNIVKALNEIGINDILVVDNLKNGRKFKNLVDLDITDYMDRDDFLTQIMAGDNFGPIEAVFHEGACSATTEWDGKYMMLNNYEYSKELLHYCLEREIPFLYASSAATYGETTVFKEEREYEGALNVYGYSKQQFDNYVRRLWQDAEEHGETLSQITGFRYFNVYGPREQHKGSMASVAFHLNNQILAGENPKLFAGSEQFKRDFIYVGDVCKVNLWFMQNGVSGIFNCGTGNAESFEEVAKAVIKHHGKGEIETIPFPEHLKGAYQEFTQADLTKLRAAGCDVEFKTVAEGVAEYMAIVNG
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: BRA6_CHITH
Sequence: MKFIIRTILIALFLIAIINESQCRRDPRKFRLSRVFEKLIEKNSRHHENERENEIGRAFDMDCVKNFFKLPQNGKMILKETEEMVFMVASGMKCSTEYKIFGAMFRDFVNEGLKEHLTCLKWQLKQYEPSAKLIENFEITEAELKVCQEKFPIYNEMKGFQKDLEDLLGPLNTYTCGAVSEDGAKDFLIFVSKGAIVEYGDISEELKKTEKEKLKDYFKDISIKTAECHIKRFENEPQAYQVNDTLNYYYKKDLVPTDPDQEDPNGYYQRLIKVEEAIDKDCVKQKLTLPENGDKAFVEPEATILIASAKTKCIKIDQLEFSNLFIDFALEDGQRHDRYYSCARYKLHQLDPNSQLAVITSSDKSHEKHCRHIEIRLHPFSIPINGYAESVGKLNEATCGVLTDDIVNVVTLKTMLLYDVKDKELKINETKELYGLVTDKLQKLARLILERVR
What is the function of this protein?
Used by the larvae to construct a supramolecular structure, the larval tube.
What are the official names of this protein?
Balbiani ring A 67 kDa protein, p67.
What are the subcellular locations of this protein?
Secreted.
Protein: PDXT_BACCR
Sequence: MVKIGVLGLQGAVREHVKSVEASGAEAVVVKRIEQLEEIDGLILPGGESTTMRRLIDKYAFMEPLRTFAKSGKPMFGTCAGMILLAKTLIGYEEAHIGAMDITVERNAFGRQKDSFEAALSIEGVGEDFVGVFIRAPYVVEVADNVEVLSKHGDRMVAVRQNQFLAASFHPELTDDHRVTAYFVEMVKEAKMKKVV
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: PSBI_WHEAT
Sequence: MLTLKLFVYTVVIFFVSLFIFGFLSNDPGRNPGREE
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.8 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: KLC2_MOUSE
Sequence: MATMVLPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLASHEAGEAEPGSQERCLLLRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKLQRSEQAVAQLEEEKQHLLFMSQIRKLDEMLPQEEKGDVPKDSLDDLFPNEDEQSPAPSPGGGDVAAQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGENKPIWMHAEEREESKDKRRDRRPMEYGSWYKACKVDSPTVNTTLRTLGALYRPEGKLEAAHTLEDCASRSRKQGLDPASQTKVVELLKDGSGRGHRRGSRDVAGPQSESDLEESGPAAEWSGDGSGSLRRSGSFGKLRDALRRSSEMLVRKLQGGGPQEPNSRMKRASSLNFLNKSVEEPVQPGGRVFLTAAL
What is the function of this protein?
Kinesin is a microtubule-associated force-producing protein that plays a role in organelle transport.  The light chain functions in coupling of cargo to the heavy chain or in the modulation of its ATPase activity.  Through binding with PLEKHM2 and ARL8B, recruits kinesin-1 to lysosomes and hence direct lysosomes movement toward microtubule plus ends.
What are the official names of this protein?
Kinesin light chain 2, KLC 2.
What is the protein family that this protein belongs to?
Belongs to the kinesin light chain family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL6_BORBR
Sequence: MSRIAKYPVELPKGVEASIQPDQITVKGPLGTLVQSLTGDVNVAQEDGKLTFVVANDSRHANAMSGTLRALVANMVTGVSKGFERKLNLVGVGYRAQIQGDAVKLQLGFSHDVVHQLPAGVKAECPTQTEIVIKGPNKQVVGQVAAEIRKYREPEPYKGKGVRYADERVVIKETKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: CHEB_DESPS
Sequence: MKNLRVLVVDDTILYRKIVSDLLREIPGIEVIGVAHNGKIALDKIRLSKPDLITLDIEMPVMNGIELLEHLKDIPDAPGAVMLSTLTSDGSRMTMKALELGAFDFILKPQEKTPAANKAALANSLKQIVKTYRLRNIGFSRTRATTPASRLSPRTTIKREIKTTDRSIKKGKAEIVVIGISTGGPNALTNMLPQIPGNIGVPILIVQHMPPVFTASLATSLNKKCQIEVKEAEDGEAIQPGIAYIAPGGKQMKISASKNGVERLIKITNDPPENSCRPSVDYLFRSVGDYFIGRATAVIMTGMGADGTKGLEVLMAKGAHSIGQDEESCVVYGMPKSVADAGLIDTVCPLNKIAQEIVHTVKLY
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS3_BRUA4
Sequence: MSFFPAQPSDKKAIEEGAAFMPRFDASGLITAVVTDARDGELLMVAHMNEEALRLTLETGIAHYWSRSRGKLWKKGETSGNLQSVVELRTDCDQDALWLKVRVAGDGPTCHTGRRSCFYRQVVAENGDISLAIEGACDHEH
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDM10_VANPO
Sequence: MIEYMNYVIKSLQSNNDYEHLTLSSRSLLNFKIPNAFKFQLSNKSTPYTYNTIDISTNKVINGSITYLYTDAKGLDKLIKDSHNINIQSIVETYNHHCKTLNINKQNVDFKSLYYGRMYYPNSHLEGMIIKKFTTNTQVVLKWVSSFNSCNIITGYFQKYGKRNFQELIVSSNDFLCGYRFLHNFIEQPSKLNNSLYNNSYISLGGEFWLAISTLSPTCATTLRYCTHSATTGRPLTLTLSFNPLFGHLSSTYSAKTSSNSAFCVQYDFNLYSIDSNLSLGCELWKQNELIQNVSQEKSKKQEIQVPPNFYNNNSNDAKQKRILNDLNTTFESSLKKIDKERAVIENFETDLYNKDFTSVWKFSTSLRDKNLCILWDGKFKGFLLSAGTELIRINTNNENNSQSLVKFYPAKLGLQLQFST
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange.  MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex).  Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins.  Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins.  May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway.  Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 10, Mitochondrial inheritance component MDM10.
What is the protein family that this protein belongs to?
Belongs to the MDM10 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria- endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: RASP2_TOXGG
Sequence: MALVLRLMGGAAGMGAKAVGGACCELGSACFRQITKGLPHPTECGCLGSLFFYLGIHDHQKFNVLVEIHELDRVPKSCSLYMTIEAGRWSATSQVVKVKGQDQRVVVEERLMVHIRQVDNEVKIFLFKKGLVKTTRLANLVLKVKEDMIDKKFPKRTWYNMKVENGKSQPRINLSLHKLDPGLPTNQSPLLQQAMLIAQQEADEKGEELKLDLAKMTAKERLTFFSQVLEGPLERLNANGGACMQFYYKAVEVKPDRWEWCYWESAAACKEGKEKEGSIPFLAISLVLPDRKNRNVFFVRYHDKDNQHDVFFRRVDRDRNLWSDGLYEFIEKLRAYRETCSTRVPSQKGADGEEKKKKKKRREDGEDSSGEKSPRKSGGKKSRRPSTSPRLDISTARRLHSPRAQVPSKSPCAHQQMYEEVMISTQSSVVGDEEPQT
What is the function of this protein?
Essential for tachyzoite invasion of host cells by controlling rhoptry secretion (PubMed:31492901).  Binds to phosphatidic acid (PA) and phosphatidylinositol 4,5-bisphosphate (PIP2) lipids and thus, likely contributes to the assembly of the machinery that docks or primes the rhoptry to the parasite cell membrane prior to the fusion with the host cell membrane (PubMed:31492901).
What are the official names of this protein?
Rhoptry apical surface protein 2, TgRASP2.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, rhoptry membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes to the extremity of the neck of the rhoptry (PubMed:31492901). Associates only with mature rhoptries (PubMed:31492901).
Protein: RS9_DESVM
Sequence: MANEFNYGTGRRKTATARTRLYAGSGQIVVNGRPFEDYFPRKSLQMIIRQPLVLTKNVERFDIKVNVCGGGVTGQAEAVRHGISRALLELEPELRGALKRAGFLTRDARKKERKKYGQRAARARYQYSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: YR024_MIMIV
Sequence: MVLSDFIYPACEGLCFPKISRTKDSNHKTYEFFNKKKHPKKYVDNSDALFLIKRARDSFLSHIKLKDKHMKKNYLTELSPEQIRGRFFLSGDKNFYCIYFYFTDEDAVFYCVFGIIEKSTGKHLLFVREFWSGSFDACCIKHNSFDYYSGDKYMEKTNVLNLPVILSNDTK
What are the official names of this protein?
Uncharacterized protein R24.
What is the protein family that this protein belongs to?
Belongs to the mimivirus R24/R907 family.
Protein: LEG9_HUMAN
Sequence: MAFSGSQAPYLSPAVPFSGTIQGGLQDGLQITVNGTVLSSSGTRFAVNFQTGFSGNDIAFHFNPRFEDGGYVVCNTRQNGSWGPEERKTHMPFQKGMPFDLCFLVQSSDFKVMVNGILFVQYFHRVPFHRVDTISVNGSVQLSYISFQNPRTVPVQPAFSTVPFSQPVCFPPRPRGRRQKPPGVWPANPAPITQTVIHTVQSAPGQMFSTPAIPPMMYPHPAYPMPFITTILGGLYPSKSILLSGTVLPSAQRFHINLCSGNHIAFHLNPRFDENAVVRNTQIDNSWGSEERSLPRKMPFVRGQSFSVWILCEAHCLKVAVDGQHLFEYYHRLRNLPTINRLEVGGDIQLTHVQT
What is the function of this protein?
Acts as an eosinophil chemoattractant (PubMed:9642261).  It also inhibits angiogenesis (PubMed:24333696).  Suppresses IFNG production by natural killer cells (By similarity).
What are the official names of this protein?
Galectin-9, Gal-9, Ecalectin, Tumor antigen HOM-HD-21.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Secreted. Note=May also be secreted by a non- classical secretory pathway (By similarity). Secreted by mesenchymal stromal cells upon IFNG stimulation (PubMed:23817958). SUBCELLULAR LOCATION: [Isoform 2]: Secreted. SUBCELLULAR LOCATION: [Isoform 3]: Secreted.
Protein: BIOB_PSEVU
Sequence: MAHHARWTLSQVTELFDKPLLDLLFEAQTIHRQHFDPRQVQVSTLLSIKTGACPEDCKYCPQSSRYKTGLETERLMEVEQVLDSARKAKNAGSTRFCMGAAWKNPHERDMPYLEQMVQGVKAMGLEACMTLGTLDETQAQRLASAGLDYYNHNLDTSPEFYGNIITTRTYQERLDTLDKVRDAGIKVCSGGIVGLGETVKDRAGLLLQLANLPTPPESVPINMLVKVKGTPLADNDDVDAFDFIRTIAVARIMMPTSFVRLSAGREQMNEQTQAMCFMAGANSIFYGCKLLTTPNPEEDKDVQLFRKLGLNPQQTDVMTGDNEQQQKLEEQIFNADTDQFYNAAAL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: AZO1_STAAB
Sequence: MKGLIIIGSAQVNSHTSALARYLTEHFKTHDIEAEIFDLAEKPLNQLDFSGTTPSIDEIKQNMKDLKEKAMAADFLILGTPNYHGSYSGILKNALDHLNMDYFKMKPVGLIGNSGGIVSSEPLSHLRVIVRSLLGIAVPTQIATHDSDFAKNEDGSYYLNDSEFQLRARLFVDQIVSFVNNSPYEHLK
What is the function of this protein?
Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines.  Requires NADPH, but not NADH, as an electron donor for its activity (By similarity).
What are the official names of this protein?
FMN-dependent NADPH-azoreductase, NADPH-dependent flavo-azoreductase, NADPH-flavin azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 2 family.
Protein: PWP3A_RAT
Sequence: MTDAKYVLCRWEKRLWPAKVLARTETSAKNKRKKEFFLDVQILSLKEKIQVKSSAVEALQKSHIENIAAFLASQNEVPATPLEELTYRRSLRVALDVLNERTSLSPESHPVENGSTPSQKGKPDADMASQVSSAPSPSFLSEDDQAVAAQCASKRRWECSPKSLSPLSASEEDLRCKVDPKTGLSESGALGTEVPAPTGDESQNGSGSQLDHGQESTTKKRQRNSGEKPARRGKAESGLSKGDSVAESGGQASSCVALASPRLPSQTWEGDPCAGVEGCDPVESSGNIRPLLDSERSKGRLTKRPRLDGGRNPLPRHLGTRTVGAVPSRRSCSGEVTTLRRAGDSDRPEEADPMSSEESTGFKSVHSLLEEEEEEEEEEEEEEEPPRILLYHEPRSFEVGMLVWLKYQKYPFWPAVVKSVRRRDKKASVLFIEGNMNPKGRGITVSLRRLKHFDCKEKHALLDRAKEDFAQAIGWCVSLITDYRVRLGCGSFAGSFLEYYAADISYPVRKSIQQDVLGTRFPQLGKGDPEEPMGDSRLGQWRPCRKVLPDRSRAARDKANQKLVEYIVKAKGAESHLRAILHSRKPSRWLKTFLSSNQYVTCMETYLEDEAQLDEVVEYLQGVCRDMDGEMPARGSGDRIRFILDVLLPEAIICAISAVEAVDYKTAEQKYLRGPTLSYREKEIFDNELLEERNRRRR
What is the function of this protein?
Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture.  Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation.  Required for efficient DNA repair and cell survival following DNA damage (By similarity).
What are the official names of this protein?
PWWP domain-containing DNA repair factor 3A, PWWP3A, Mutated melanoma-associated antigen 1, MUM-1, PWWP domain-containing protein MUM1.
What is the protein family that this protein belongs to?
Belongs to the PWWP3A family.
What are the subcellular locations of this protein?
Nucleus. Note=Recruited to DNA damage sites via its interaction with the BRCT domain of TP53BP1.
Protein: YCIB_SHEB2
Sequence: MKQLLDFLPLVIFFAVYKFFDIYIASGALIAATALQLIVTYALYKKLEKMHLITFAMVTVFGTLTLVFHDDSFIKWKVTIIYSLFAIALGVSQLLNKSILKSMLGKEMQVEDKIWARVTWYWVVFFASCGLVNIYVAFSLPLETWVNFKVFGLTALTLINTVLTVFYLYKHLPEDQRKELK
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KPRS_OCEIH
Sequence: MTSSYKDSSLKVFSLNSNPELANEIATHIGTNLGKCTVSKFSDGEVQINLEESVRGCDVYVVQSTCAPVNQHIMELLIMIDALKRASAKSINIVMPYYGYARQDRKARSREPIAAKLVADLIEKAGANRVITLDLHAPQIQGFFDIPIDHLQGVPILSSYFEQKNLDDVIVVSPDHGGVTRARKMADRLKAPIGIIDKRRPKPNVAEIMNIIGNIEGKTAILIDDIIDTAGTITLAANALIENGAKEVYACCTHPVLSGPAIERIDNSKIKELVITDSIPLPDEKFSTKITALSVAPLIGEAIIRVHEMQSVSILFD
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase, RPPK, 5-phospho-D-ribosyl alpha-1-diphosphate synthase, Phosphoribosyl diphosphate synthase, Phosphoribosyl pyrophosphate synthase, P-Rib-PP synthase, PRPP synthase, PRPPase.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_METVS
Sequence: MDLRKKIRIIDDFPKKGISFKDVTPILKDPKSMKHTTKEITKYLEDKNIDVIVGPEARGFLFGILVAQELDLGFVPVRKPGKLPFKTFSVDYALEYGLDRLEIHSDSIEKGQNVAVVDDLLATGGTVLGVTKLVEKIGGNVSALSFVIELTNLNGRDKLKGYNVQSLVKYDDL
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERA_MYCAP
Sequence: MKVCIISILGRPNVGKSSLLNKIIKYDLAIVSNVPQTTRDQIMGVYTEDGYQFVFVDTPGIHKPLNLLGESLNKEAFSSLKDIDCVLFLSPVNEDIKSGDKLILERITNAKNKIAVISKIDLAKSPDEIAKKIDGLKEYGFNKIISVSNKNDKSVDSLIEILKEYAYNAPPFYDEDYITDKSMRFMAKEYIRESAINLLTDELPHSIAVEVQDFIEEDDRITINAIIYVKKDSQKGILIGKGASMIKKIGTNARMKMSHQFDTKVTLNLKVKVSNKWINDKSALKKFGYN
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: KDUI_ECOSE
Sequence: MDVRQSIHSAHAKTLDTQGLRNEFLVEEVFVADEYTMVYSHIDRIIVGGIMPITKTVSVGGEVGKQLGVSYFLERRELGVINIGGAGTITVDGQCYEIGHRDALYVGKGAKEVVFASIDTATPAKFYYNCAPAHTTYPTKKVTPDEVSPVTLGDNLTSNRRTINKYFVPDVLETCQLSMGLTELAPGNLWNTMPCHTHERRMEVYFYFNMDDDACVFHMMGQPQETRHIVMHNEQAVISPSWSIHSGVGTKAYTFIWGMVGENQVFDDMDHVAVKDLR
What is the function of this protein?
Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.
What are the official names of this protein?
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase, 5-keto-4-deoxyuronate isomerase, DKI isomerase.
What is the protein family that this protein belongs to?
Belongs to the KduI family.
Protein: ERPA_FRATN
Sequence: MSEVVQSVDPINFTEAASLKVKELIEEEGDNSLSLRVYITGGGCSGFQYAFAFDNEVKEDDMVITKNGVRLLVDSMSFQYLVGADVDYKDDVEGAYFVIRNPNAKTTCGCGSSFSV
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.