PharMolix/UniProtQA huggingface dataset:
Protein: SCPB_STRPD
Sequence: MTYLSQIEALLFVAGEEGLSLRHLASMLSLTPTALQQQLEKLSQKYEKDQHSSLCLIETANTYRLVTKEGFAELLRAYAKTPMNQSLSRASLEVLSIVAYKQPITRIEIDDIRGVNSSGALSKLLAFDLIREAGKKDVVGRPHLYATTDYFLDYMGINHLDELIEVSAVEPADEEIALFRTQD
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein B.
What is the protein family that this protein belongs to?
Belongs to the ScpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: PYRC_GEOSL
Sequence: MNLLIKGGRVIDPSQGIDEVLDILVENGAIKELGKGLAAPAGAGVVDAAGLIVTPGLIDMHVHLRDPGLEYKEDIVTGTRAAAAGGFTSVACMPNTKPVNDNKAVTSYIVAKAKAEGLVNVFPVGSITQGSKGDALAEMGDLKEAGCVAVSDDGRPVTSSELMRRALEYAKGMGIMVISHAEDLSLVGEGVMNEGFVSTELGLKGIPWAAEDAATARDVYLAEFTNSPLHIAHVSTMGSLRIIRNAKARGVKVTCETAPHYFSLTDDAVRGYNTNAKMNPPLRTADDLAAVKEALKDGTIDAIATDHAPHHLDEKDVEFNVALNGIIGLETSLPLSLKLVEEGVLTLPALVEKMACNPAAILGIDRGTLRQGAVADITVIDPAAVWTVEAGALASKSKNSPFLGWEMKGAAAYTIVGGTVVHSRG
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: TBB5_HUMAN
Sequence: MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEEDFGEEAEEEA
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta chain, Tubulin beta-5 chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: GALS1_ARATH
Sequence: MRKEVLPPVLSTTTVCFEKKPIIATLLALSLVMIVWNLPPYYHNLISTARPCSAVTTTTTTTLLSSSNFTSAENFTTSLSTTTAAASQKYDSTPSDPNKRVFQPFGNAAALFVLMGAYRGGPTTFSVIGLASKPIHVYGKPWYKCEWISNNGTSIRAKAQKILPDWGYGRVYTVVVVNCTFNSNPNSDNTGGKLILNAYYNESPKLFERFTTLEESAGIYDESKYSPPYQYDYLYCGSSLYGNVSASRMREWMAYHAWFFGDKSHFVFHDAGGVSPEVRKVLEPWIRAGRVTVQNIRDQSQYDGYYYNQFLIVNDCLHRYRYAANWTFFFDVDEYIYLPHGNTLESVLDEFSVNTQFTIEQNPMSSVLCINDSSQDYPRQWGFEKLLFKDSRTKIRRDRKYAIQAKNAFATGVHMSENIVGKTLHKTETKIRYYHYHNTITVHEELCREMLPNSAKKKVTLYNKLPYVYDDNMKKLVKTIKEFEQKKLGTDVKNFS
What is the function of this protein?
Involved in the biosynthesis of beta-1,4-galactan.  Can transfer galactose residues from UDP-galactose to beta-1,4-galactopentaose in vitro.  Forms specifically beta-1,4-galactosyl linkages and can add successive beta-1,4-galactosyl residues to the acceptor.  Beta-1,4-galactans are abundant polysaccharides in plant cell walls and are found as side-chain of rhamnogalacturonan I, which is a major component of pectin.
What are the official names of this protein?
Galactan beta-1,4-galactosyltransferase GALS1, Beta-1,4-galactan synthase, Galactan synthase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 92 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass membrane protein.
Protein: PYRG_SALA4
Sequence: MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQLAVDIGREHALFMHLTLVPYLAAAGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISMKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIYEEANPAGEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVTVNIKLIDSQDVETRGVEILKDLDAILIPGGFGYRGVEGKIATARYARENNIPYLGICLGMQVALIEFARNVAGMDNANSTEFVPDCKYPVVALITEWRDEDGNVEVRSEKSDLGGTMRLGAQQCQLSDDSLVRQLYGAPTIVERHRHRYEVNNMLLKQIEAAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAANEHQKRQAK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: CO1A1_HIPAM
Sequence: GPMGPSGPRGIPGPPGAPGPQGFPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPSGPQGARGIPGTAGIPGMKGHRGFSGIDGAKGDAGPAGPKGAPGQMGPRGIPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGARGSEGPQGVRGEPGPPGPAGAAGANGAPGIAGAPGFPGARGPSGPQGPSGPSGPKGNSGEPGAPGSKGDTGAKGEPGPTGIQGPPGPAGEEGKRGARGEPGPAGIPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGIPGAKGITGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGIPGPAGPPGEAGKPGEQGVPGDIGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGIQGMPGERGAAGIPGPKGDRGDAGPKGADGSPGKDGVRGITGPIGPPGPAGAPGDKGEAGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGTGPPGPIGNVGAPGPKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPVGKRGETGPAGRPGEVGPPGPPGPAGEKGAPGADGPAGAPGTPGPQGIAGQRGVVGIPGQRGERGFPGIPGPSGEPGKQGPSGTSGERGPPGPMGPPGIAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPIGPVGARGAAGPQGPRGDKGETGEQGDRGIKGHRGFSGIQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGSPGKDGINGIPGPIGPPGPRPGPPGPPGPPGPP
What is the function of this protein?
Type I collagen is a member of group I collagen (fibrillar forming collagen).
What are the official names of this protein?
Collagen alpha-1(I) chain, Alpha-1 type I collagen.
What is the protein family that this protein belongs to?
Belongs to the fibrillar collagen family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix.
Protein: RSMG_BACC1
Sequence: MNIEQFQSMLEEKGITLSSRQLEQFEIYFETLVEWNEKMNLTAITEKEEVYLKHFFDSITAAFYYDFSKPFSICDVGAGAGFPSIPLKICFPHLKVTIVDSLQKRINFLNHLAQKLELSDVAFCHDRAETFGKKEGVREAYDIVMARAVARLSVLSELCLPLVKVGGTFIAMKGAAANEEIENGKYALEVLGGDLKEMSTFQLPFEESERNILLIEKKRKTPKKYPRKPGTPNKLPIEK
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURQ_STRCO
Sequence: MTARIGVVTFPGSLDDRDTQRAIRVAGAEPVALWHKDKDLKQVDAVVLCGGFSYGDYLRAGAIARFSPVMDTVIDQAKAGLPVLGICNGFQILTEAHLLPGGMLGNDHLHFICRDQKLRVENADTSWTSDYTAGQEIHIPLKNMDGRYVADRRTLDELEAEGRVAFRYLDMNPNGSLNDIAGITNAAGNVVGLMPHPEHAVESLIGTGRTDGLPFFTSILKKLVNA
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU1_RHIEC
Sequence: MAKSKFERNKPHVNIGTIGHVDHGKTSLTAAITKYFGEFKAYDQIDAAPEEKARGITISTAHVEYETPARHYAHVDCPGHADYVKNMITGAAQMDGAILVCSAADGPMPQTREHILLARQVGVPAIVVFLNKVDQVDDAELLELVELEVRELLSSYDFPGDDIPVVKGSALAALEDSDKKIGEDAIRELMAAVDSYIPTPERPVDQPFLMPIEDVFSISGRGTVVTGRVERGIIKVGEEVEIVGIRPTSKTTVTGVEMFRKLLDQGQAGDNIGALIRGVNRDGVERGQILCKPGSVKPHKKFKAEAYILTKEEGGRHTPFFTNYRPQFYFRTTDVTGIVTLPEGTEMVMPGDNVTVDVELIVPIAMEEKLRFAIREGGRTVGAGIVASIVE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu 1, EF-Tu 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_SYNJA
Sequence: MEGFLDLYLELNVPSPVEEATWHRWFEVWLRELGVTDPCELSLCLTSDEHIRQLNREFRHIDAPTDVLAFAAEETSTPVELQKITGVRLLGDIVISVPTACAQAKAQGQRLSRELAWLASHGLLHLLGWDHPDELSLQRMLQQQHHLLAAIQEDLEVTHGQQP
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYP15_RHIO9
Sequence: MPEDSNTNDNNKRPLEDNNAVDGESDDDIGPMLPPPPGEDAPRKKKRTLAHEKLYLDQLPCADMYEKSYMHRDVLSQVAVTKKDFIITTSVDGHLKFWKKTASGIEFVKHYKSHLSSIVDISISANHELLATISDDTTLKVYDITNFDMINMIKLRYKPKSVCWIHQSGQAQALVAVSEADNSNIHIYDGHADGKPLHTLSKMHSKPVHIIEFNSRFNCVVSVDAIGMIEYWSPEAPFALPDNLDFELKSQTDLYEFRKKKSVPTCLTFSPDGLSFATMSFPDRQVRLFKFLRGKMFREYDESLQAVSEMQQAGTTIHHLDDMEFGRRLAVEKELEKSNQARFVNAVFDNSGNFIIYGSLLGVKIVNIRTNKVVCLLGKSESNRFVNVSLYQGAPKKKAVYTLAMIASENAALKESQELDPTLFCTAFNKNRFYMMTRREPFDDINQKAERDIFNEKPSREEQTVAATQERKQILGTSAIIRTTSGDIHMRLFPDAAPKAVENFTTHAKNGYYDNLIFHRVIKGFMIQTGCPFGDGTGGESIWGDDFEDEFSREFRHDRPYTVSMANAGPNTNGSQFFITVAPTTWLDNKHSVFGRVTAGMDVVHSIESAKVDKTNKPLDDIKIINIDIR
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase cyp15, PPIase cyp15, Cyclophilin cyp15, Rotamase cyp15.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family.
Protein: MDFA_EDWI9
Sequence: MQNHLSSTRRLGRRALLFPLCLVLYEFATYIGNDMIQPGMLSVVQTFGVDESWVPTSMTAYLAGGMFLQWLLGPLSDRIGRRPVMLIGTLYFAATCLAILLTNSIEQFTLMRFLQGISLCFIGAVGYAAIQESFEESVCIKITALMANVALIAPLLGPLAGAAWVHLFPWEGMFILFAALSLLAFLGLYKAMPETATRRGEKLSLSALGRDYTLVLKNRRFLCGSLACGFASLPLLAWIAQSPVIIISGEGLSSYDYGMLQVPIFGMLILGNLTLARLSGRRPVRRLIQLGAWPMVGGLAIAAASTLYSAHAYLWMTAGLSLYAFGIGLANAGLYRLTLFSSTMSKGTVSAAMGMISMFIYTLGIEVGKYAWLLGGNGAFNLFNLISGLLWLALIARMLRDQLVGRMAGR
What is the function of this protein?
Efflux pump driven by the proton motive force.  Confers resistance to a broad spectrum of chemically unrelated drugs (By similarity).
What are the official names of this protein?
Multidrug transporter MdfA.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. MdfA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VIRB7_BRUAB
Sequence: MKKVILAFVATAFLAGCTTTGPAVVPVLDGKPRVPVNKSVPAKPPLAQPNPVDTYED
What are the official names of this protein?
Type IV secretion system putative lipoprotein virB7.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: RS15_STACT
Sequence: MAISQERKDEIIKEYRVHETDTGSPEVQIAVLTAEINALNEHLRTHKKDHHSRRGLLKMVGRRRHLLNYLRKKDIQRYRELIKSLGIRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: MDM12_CRYNB
Sequence: MSLDINWSLLSQPDESATDQLSESLIALLNAQLAEAHRPSFIGPITVTAFDFGNAGPDLEVKDIRDVWRVFDQGDDEGDFAEEEKQREKEREERDKLRNEALKSSLDGERYELVDRYSSTEGTSSFEYQPEYDIHEQHGDDYRIRGRRPLSYTFGYPHDRLAVHRSSSSRSFIPFPFDHPPPALHIPSTPGLNPSLVSHPISARFSRRPMSIAASAAPRPTPRRRPIEPSSTSPSPPAHPAGLPPKASSSSIPSLQLHLRLSHASDLHLTLLTSLQVNYPSALFMALPLKLSITGFQLNADIVMAYSGEKNRVHLTIVDDESNPAHKEDKQIPLGQRLLSNLQIESEIGHADAHVLRNVGKVERFIVDVVRKTLVDELVFPNFHTVAL
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.  The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 12, Mitochondrial inheritance component MDM12.
What is the protein family that this protein belongs to?
Belongs to the MDM12 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: NIKR_ECOLI
Sequence: MQRVTITLDDDLLETLDSLSQRRGYNNRSEAIRDILRSALAQEATQQHGTQGFAVLSYVYEHEKRDLASRIVSTQHHHHDLSVATLHVHINHDDCLEIAVLKGDMGDVQHFADDVIAQRGVRHGHLQCLPKED
What is the function of this protein?
Transcriptional repressor of the nikABCDE operon.  Is active in the presence of excessive concentrations of intracellular nickel.
What are the official names of this protein?
Nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: RL9_BUCAP
Sequence: MEVILLSKIKKLGDSGAIVHVKSGYARNFLIPKGKAILASKKNIESFEAQRVELEKENISKLLIAQSRAEKIKTIKSITIPSKVGKEGKIFGSIGIRNIIKEMNLLGIKVNKKEIKLPNGVLRQVGEHKVIFQPHNEVCEYFIVNIISKK
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: ACCD_PORPU
Sequence: MSLSNWPLKKEQSKAHNIKSTKQITIPDGLWVKCFDCGLLMYSKVLKRNLKVCPQCSYHFQASSNERIDQLIDQGSWEPMDVHLISTDPLGFKDQKLYSQRLKDTAFKTSLQDAVQTGVGTMLGQKVCLGIMDFRFMGGSMGSVVGEKLTRLLEKATQERLPAIILCASGGARMQEGMLSLMQMAKISSALEMHKKENLLYLSVLTSPTTGGVTASFAMLGDLIIAEPKALIAFAGRRVIEQTIKEDLPDNFQSSEYLFEHGFLDLIVPRTQLRSKLIQILHLHTNNN
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: 6PGDH_GLUOX
Sequence: MRIGIIGLGRMGGNIAVRLTRHGHDVVVHDRTSEVTTSVVGRCEAGRATPADTLADMAKLLEGDEHRVVWVMLPAGAITEDCVQQLGGLLGRGDIIIDGGNTYYKDDVRRSAELAEKGISYVDVGTSGGVWGLERGYCMMFGGTKETAEYIDPILSALAPGIGDVPRTPGRDEAGHDPRAEQGYLHCGPAGSGHFVKMVHNGIEYGMMQAFAEGFDIMKSKNSPILAEKDRFELNMGDIAEVWRRGSVVSSWLLDLTAEALTRSETLNEFSGEVADSGEGRWTIEAAIEEDVPAPVMTAALFTRFRSRSGNNFAEKILSAQRFGFGGHVEKK
What is the function of this protein?
Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NAD to NADH.
What are the official names of this protein?
6-phosphogluconate dehydrogenase, NAD(+)-dependent, decarboxylating, 6PGDH.
What is the protein family that this protein belongs to?
Belongs to the 6-phosphogluconate dehydrogenase family.
Protein: ATC1_SCHPO
Sequence: MSVQYDAFSVEQTCADLETDMYNGLSSLQEITRRNKVHGDNDLKVEDEENMVVQFLKQFVKDPLILLLFASSAISVTLGNIDDAISIALAIVIVVTVGFVQEYRSEQSLKALNNLVPHYCNVIRSGKTEHIVASKLVPGDLVILQIGDRVPADLRIVEATELEIDESNLTGENSPRKKSSEAISSNISLTERNNIAFMGTLVRHGHGRGIVVATGSDTEFGRVFLTMQQTEKPKTPLQNSMDDLGKQLSLISLIGIAVIVLVGFFQGKNWLEMLTIGVSLAVAAIPEGLPIIVTVTLALGVLRMSKKRAIIRRLPSVETLGSVNVICSDKTGTLTMNHMTVTKIYTCGMLAAFSLPESEHIELSVRRTVGIEKALLAAALCNNSKVHNKADSILDTTCPWAGFPVDVALIECSERFGLKDPRETYSRISEVSFSSERKYMSVAVQYNSSKMNFMKGATEQVLSSCAYFSDQDGVQHELTAEMKENIQRNEFEMAASGLRIIAVASGINTNKLVFHGLFGINDPPRPQVRESVQYLMTGGVRVIMITGDSVVTAISIARSLGMAIPSNDEEAIRNYALTGAQLDDLDSSSLRDAVSRVVVFARTTPQHKMKIVEALQSLGDVVAMTGDGVNDAPALKLADIGIAMGRQGTDVAKEAADMILTDDSFATILSAVEEGKGIFNNIKNFITFQLSTSVAALSLIAISSVFGFQNPLNAMQILWINILMDGPPAQSLGVESVDEDVMMKPPRPRNAPIISVQLLQRVLLSAFIIVTVTIVVFRVQMQDGNVTARDTTMTFTCFVFFDMFNALACRSETKSVFKLGIFSNRMFNIAVGGSLIGQALVVYASPFQRIFQTEAIGLKDVLILLACTSSVLWVDEIRKWYRRRKGLVRTKSNYLLRNV
What is the function of this protein?
Transports calcium and manganese ions into the cell.  Regulates cell morphogenesis through control of manganese and calcium homeostasis.
What are the official names of this protein?
Calcium-transporting ATPase 1, Golgi Ca(2+)-ATPase.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ATP6_GLAP5
Sequence: MAGQTTADYIGHHLSFLKTGDGFWNVHLDTLFFSLVAGATFLFFFSRVAKNATDGVPGKFQCFVEMIVEWVDGLVKDNFHGSREVVAPLALTVFCWVFVMNAIDLIPVDYPPQFAALLGIDYLRAVPTADISATLGMAICVFCLIIFYTIKSKGFSGFVKEYTLHPFNHWAFIPVNFVLEIVTLLAKPISLAFRLFGNMYAGELIFILIAVMYMADNFLLQALGLPLHLAWAIFHILVITLQAFIFMMLTIVYLSIAYNKADH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RDRP_CGMVS
Sequence: MANINEQINNQRDAAASGRNNLVSQLASKRVYDEAVRSLDHQDRRPKMNFSRVVSTEHTRLVTDAYPEFSISFTATKNSVHSLAGGLRLLELEYMMMQVPYGSPCYDIGGNYTQHLFKGRSYVHCCNPCLDLKDVARNVMYNDMITQHVQRHKGSGGCRPLPTFQIDAFRRYDSSPCAVTCSDVFQECSYDFGSGRDNHAVSLHSIYDIPYSSIGPALHRKNVRVCYAAFHFSEALLLGSPVGNLNSIGAQFRVDGDDVHFLFSEESTLHYTHSLENIKLIVMRTYFPADDRFVYIKEFMVKRVDTFFFRLVRADTHMLHKSVGHYSKSKSEYFALNTPPIFQDKATFSVWFPEAKRKVLIPKFELSRFLSGNVKISRMLVDADFVHTIINHISTYDNKALVWKNVQSFVESIRSRVIVNGVSVKSEWNVPVDQLTDISFSIFLLVKVRKVQIELMSDKVVIEARGLLRRFADSLKSAVEGLGDCVYDALVQTGWFDTSSDELKVLLPEPFMTFSDYLEGMYEADAKIERESVSELLASGDDLFKKIDEIRNNYSGVEFDVEKFQEFCKELNVNPMLIGHVIEAIFSQKAGVTVTGLGTLSPEMGASVALSSTSVDTCEDMDVTEDMEDIVLMADKSHSYMSPEMARWADVKYGNNKGALVEYKVGTSMTLPATWAEKGKAVLPLSGICVRKPQFSKPLDEEDDLRLSNMNFFKVSDLKLKKTITPVVYTGTIRERQMKNYIDYLSASLGSTLGNLERIVRSDWNGTEESMQTFGLYDCEKCKWLLLPAEKKHAWAVVLASDDTTRIIFLSYDESGSPIIDKKNWKRFAVCSETKVYSVIRSLEVLNKEAIVDPGVHITLVDGVPGCGKTAEIIARVNWKTDLVLTPGREAAAMIRRRACALHKSPVATNDNVRTFDSFVMNRKIFKFDAVYVDEGLMVHTGLLNFALKISGCKKAFVFGDAKQIPFINRVMNFDYPKELRTLIVDNVERRYVTHRCPRDVTSFLNTIYKAAVATTSPVVHSVKAIKVSGAGILRPELTKIKGKIITFTQSDKQSLIKSGYNDVNTVHEIQGETFEETAVVRATPTPIGLIARDSPHVLVALTRHTKAMVYYTVVFDAVTSIIADVEKVDQSILTMFATTVPTKXQLMQNSLYVHRNIFLPVSKTGFYTDMQEFYDRCLPGNSFVLNDFDAVTMRLRDNEFNLQPCRLTLSNLDPVPALIKNEAQNFLIPVLRTACERPRIPGLLENLVAMIKRNMNTPDLAGTVDITNMSISIVDNFFSSFVRDEVLLDHLDCVRASSIQSFSDWFSCQPTSAVGQLANFNFIDLPAFDTYMHMIKRQPKSRLDTSIQSEYPALQTIVYHPKVVNAVFGPVFKYLTTKFLSMVDSSKFFFYTRKKPEDLQEFFSDLSSHSDYEILELDVSKYDKSQSDFHFSIEMAIWEKLGLDDILAWMWSMGHKRTILQDFQAGIKTLIYYQRKSGDVTTFIGNTFIIAACVASMLPLDKCFKASFCGDDSLIYLPKGLEYPDIQATANLVWNFEAKLFRKKYGYFCGKYIIHHANGCIVYPDPLKLISKLGNKSLVGYEHVEEFRISLLDVAHSLFNGAYFHLLDDAIHELFPNAGGCSFVINCLCKYLSDKRLFRSLYIDVSK
What is the function of this protein?
The replicase small subunit is a methyltransferase active in RNA capping and an RNA helicase.  It also acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs.  May mediate silencing suppression through either inhibition of HEN1-mediated siRNA or siRNA demethylation (By similarity).
What are the official names of this protein?
Replicase large subunit, 186 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the tobamovirus RNA-directed RNA polymerase family.
Protein: HTRA3_MOUSE
Sequence: MQARALLPATLAILATLAVLALAREPPAAPCPARCDVSRCPSPRCPGGYVPDLCNCCLVCAASEGEPCGRPLDSPCGDSLECVRGVCRCRWTHTVCGTDGHTYADVCALQAASRRALQVSGTPVRQLQKGACPSGLHQLTSPRYKFNFIADVVEKIAPAVVHIELFLRHPLFGRNVPLSSGSGFIMSEAGLIVTNAHVVSSSSTASGRQQLKVQLQNGDAYEATIQDIDKKSDIATIVIHPKKKLPVLLLGHSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQRDGKELGLRDSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVAAGISFAIPSDRITRFLSEFQNKHVKDWKKRFIGIRMRTITPSLVEELKAANPDFPAVSSGIYVQEVVPNSPSQRGGIQDGDIIVKVNGRPLADSSELQEAVLNESSLLLEVRRGNDDLLFSIIPEVVM
What is the function of this protein?
Serine protease that cleaves beta-casein/CSN2 as well as several extracellular matrix (ECM) proteoglycans such as decorin/DCN, biglycan/BGN and fibronectin/FN1.  Inhibits signaling mediated by TGF-beta family proteins possibly indirectly by degradation of these ECM proteoglycans (PubMed:15206957).  May act as a tumor suppressor.  Negatively regulates, in vitro, trophoblast invasion during placental development and may be involved in the development of the placenta in vivo.  May also have a role in ovarian development, granulosa cell differentiation and luteinization (By similarity).
What are the official names of this protein?
Serine protease HTRA3, High-temperature requirement factor A3, Pregnancy-related serine protease, Toll-associated serine protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1C family.
What are the subcellular locations of this protein?
Secreted. Note=Secretion increased during decidualization of endometrial stromal cells.