PharMolix/UniProtQA huggingface dataset:
Protein: RL14_SHESW
Sequence: MIQMQSTLDVACNSGARRVQCIKVLGGSHRRYAGIGDIIKVSVKEAIPRAKAKKGDVYNAVVVRTKKGVRRPDGSVIRFDRNAAVLLNNNLQPIGTRIFGPVTRELRNEQFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RS9_THEFY
Sequence: MVEPTGIEDVQEYDENSEEYPAEYTTETPETVGETYIPTAVGPSLGTGRRKTAVARVRVVPGTGEWKINGKSLEEYFPNKVHQQLIKEPLATLGFEGAYDVFARLNGGGTSGQAGALRHGLARALAAMDPEHNRPPLKKAGFLTRDARKVERKKAGLKKARKAPQYSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: MNMC_BURO1
Sequence: MPDRLVSATLALRDDGTLVSPEFGELHRGASGTLARAHRTFVAGNGLPARWQRRRTFTIVTTAFGAGAGFLAAWVAWRDDPARCERLHVVAVEPHPFSRDDLHRAVSHMVVDTTISADVDALLDAWPILVPGLHRLEFDEGRVVLTLAFGDTIDLLKKLVARADAFFLDGAAASGDGIRALAKLAGEHATFATHAKSDDVKHALGETGFTFREVDDRLVGDYAPRWRARRHEPPRALPVAARRAIVIGAGLAGCAVVERLAARGWDVTLIERHERIASEASGNPAGVFHPLMTRDDNVASRLTRGGFLHALARWRALERAGHAFSRSTHGMLHLAESADDFARMRDAFDAFGPPSDYATLLDADAARAHLNLPVAQGGLLFPHGGAVWPAGLCVAQYAAAGERVRLLASTCVARLERRDDTWHALDDTGATLADAPVVVLANAGDAARLAGLRHVTLQPVRGQLTLLPPGTTAPLPCPAIGDGYAVPLDDGTLLIGATFEPDDTDPAMRAAGHAENLDRVRHLLPGLIGALPDPATLRGRVAFRWVVGDRLPLIGPLADETQATANARALGGAQARDLPRMPGLYGAFGFGSRGLVWAALGAELIASQLEGEPWPLERELADAVDPARFLIRALRARRVGSAG
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
Protein: RL32_ALKMQ
Sequence: MAVPKRKTSKSKRDMRRASNSKFVAPGYVKCPQCHETKLPHRVCPDCGHYNGKEVIAAE
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: TAM_AGRRK
Sequence: MAWSAGQYVKFEDERTRPARDLLAQVPLTRIDRAIDLGCGPGNSTELIVERYGVAGVSGLDSDDNMLEAARARMPGTDFVKADLATWLPDEPVDLLFANAVFQWLPNHLEIFDRLMDGLKSGGVLAIQMPDNLTEPSHLMMEETAKNGPWSDAFAKKSVRRNPLPAPSVYYNRLIGKSARIDLWHTNYNHALENAAAIVEWVKATGLRPYLDHAGAEHRDAFTADYLARIEKAYPPLTDGKVLLRFPRLFLVAVKK
What is the function of this protein?
Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
What are the official names of this protein?
Trans-aconitate 2-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Tam family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_PONAB
Sequence: MAPSRKFFVGGNWKMNGRKQSLGELIGTLNAAKVPADTEVVCAPPTAYIDFARQKLDPKIAVAAQNCYKVTNGAFTGEISPGMIKDYGATWVVLGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKVIADNVKDWSKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSNVSDAVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPEFVDIINAKQ
What is the function of this protein?
It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
What are the official names of this protein?
Triosephosphate isomerase, TIM, Methylglyoxal synthase, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RN207_CAEBR
Sequence: MEENPLRCTICKNDFEEPILFSCQHTTCRKCSNGSPSCKTCSPGPSTSRSHTPQPDKLAAFLLDASKEEMEQCANCEQITLPMFYCETCQQSLCLACRNVTHQARMFSSHKIISSEERSKVYSSSLCKDHNEPYILYCSDVRKLVCIQCFNGRPLEERHSFISIEQGHRMCLEKIEQSAAKLRFYQSERQEELNVRQRILDEASNFDDAKTSLYQLCQQIIDTVMTTRETLAKELVKQQEQSDEQCKRQIKEIEAVMGPVRLCLFSAQILCTTASKLDVLQLCPQLQKRISVLLDKTVDKLPVSSTPDSIEVRSDLAKSLEPYLGMSAAWCPISVSREGSSSNSYKRGSGSHKALSMLSKFQTTIDLAGAFGQLFGKVEHPLRQLVVELSSISQQVLETQRDLTIRRCIIEKEDVEKLVKMCKKIEASLGMHSAALDGMQSEMQEIWQEQLDRVRRQQIIYREKVEEILNLRETARQILTAAKQMVPYVSCILNMNAMIAPKRCHPPDPAPMESICLEITGIEPNSQNRIMAIEKEEENRRLNQEAKKKEELAGQSAAMKSLKHGKTKRKEMHHRMMLNTNRERSPGGTDSALTSPCIRRLTSTALKEETASELDAEEILDEIFELSGEQYEEVVDGTLTEEDRCSSALLLSLELQNESVSPLPSLEQLLGRISLASRVTSDIGFSRGAMLQSLNDVFALQKPPTPENISVSEERNVLASAVRNAEKRKSGAGLPTTSEKEEMIENDEIIVEKETETEKKKVIRRRVKKAECEQSEEDVTTTFTFGPPPDCPFVPQEIFDKLGESDEKLGTFEAKERVLQSLKQKMNQKNGIDNDN
What are the official names of this protein?
Probable RING finger protein 207 homolog.
Protein: SYT_CAUSK
Sequence: MIDLIFPDGSARQYADGSTGRDVAASISKSLEKKALLIKLDGKLLDLDRPLTPDLLGGGNRFEIITRDSPDALEVIRHDTAHVLAEAVQELFPGTQVTIGPNVEDGFYYDFARDEPFSLDDLPKIEERMRQIVDRDEKIRREEVDRDAAIADFEAMGESYKAQIIRDLPASDTITVYHQGEKWKDLCRGPHLPSTKAVGKAFKLTKLAGAYWRGDQNNAQLQRIYGTSWATEADLEAHLKRIEEAERRDHRKLGKTMDLFHIQEEGKGMVFWHPKGWTLYLALEAYMRRRLDAAGYREVKTPQILDKSLWERSGHAEKFGHAMFMCESAEGEVLAVKPMNCPGHIQIFNVGQKSYRELPLRMAEFGACHRYEPSGAMHGIMRVRAFTQDDAHIFCREEQVTEESARFIELLRSVYSDLGMHLADTKFSTRPELRAGEDAVWDKAEAALSAAAEAAGETLVLQEGEGAFYGPKLEFSLKDAIGRVWQCGTLQLDFVLPERLDAEYVAEDGSKKRPVMLHRAILGSFERFIGILLENYAGHLPLWLAPVQVVVATITSDADDYAQRVAERLTSMGIRAEVDFRNEKINYKIREHSLAKVPVIAVVGRKEAENGEVALRRLGGEGQKVLSLEDAVRALTEEATPPDLARDRAVAAPAELAQA
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPA_EDWI9
Sequence: MSKPIQMERGVKYRDADKMALIPVKSVAVEREQLLRKPEWMKIKLPADSSRIQGIKAAMRKNGLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPFCDVAHGRPLAPDTNEPEKLAQTIADMGLRYVVITSVDRDDLRDGGAQHFADCIHAIRAKSPQIRIETLVPDFRGRMDRALEILHDNPPDVFNHNLENIPRLYRQVRPGANYEWSLRLLQQFKQQHPQIPTKSGLMVGLGETNQEIIEVMRDLRAHGVTMLTLGQYLQPSRHHLPVQRYVSPEEFAEMKAEALAMGFTHAACGPFVRSSYHADLQAQGMEVK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14_SHIB3
Sequence: MAKQSMKAREVKRVALADKYFAKRAELKAIISDVNASDEDRWNAVLKLQTLPRDSSPSRQRNRCRQTGRPHGFLRKFGLSRIKVREAAMRGEIPGLKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: VAMP8_PONAB
Sequence: MEEASEGGGNDRVRNLQSEVEGVKNIMTQNVERILARGENLEHLRNKTEDLEATSEHFKTTSQKVARKFWWKNVKMIVLICVIVFIIILFIVLFATGAFS
What is the function of this protein?
SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes.  SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion.  VAMP8 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane via its interaction with the STX17-SNAP29 binary t-SNARE complex.  Also required for dense-granule secretion in platelets.  Also plays a role in regulated enzyme secretion in pancreatic acinar cells.  Involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells.  Involved in the homotypic fusion of early and late endosomes.  Participates also in the activation of type I interferon antiviral response through a TRIM6-dependent mechanism (By similarity).
What are the official names of this protein?
Vesicle-associated membrane protein 8, VAMP-8, Endobrevin, EDB.
What is the protein family that this protein belongs to?
Belongs to the synaptobrevin family.
Protein: MNME_SHESM
Sequence: MTTDTIVAQATAPGRGGVGIIRISGDKATDVAMAVLGHLPKPRYADYCDFKNASGQVIDQGIALFFKGPNSFTGEDVLELQGHGGQIVLDMLIKRVLEVEGIRIAKPGEFSEQAFMNDKLDLTQAEAIADLIDATSEQAAKSALQSLQGEFSKEVHELVDQVTHLRLYVEAAIDFPDEEVDFLSDGKIANALYKIIDKLSVVQASAKQGSIIREGMKVVIAGRPNAGKSSLLNALAGKESAIVTEIAGTTRDVLREHIHLDGMPLHIIDTAGLRDTTDTVEQIGIERAWNEINSADRVLFMVDGTTTDAVDPHDIWPDFIDRLPANLGVTVVRNKADLTGENLAMTEEKGYSVYRISAKTGLGVEELKQHLKSLMGYQSNLEGGFIARRRHLEALDVAASHLQLGKEQLEIYLAGELLAEELRMAQLALSEITGRFTSDDLLGKIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEXA_ECOK1
Sequence: MKALTARQQEVFDLIRDHISQTGMPPTRAEIAQRLGFRSPNAAEEHLKALARKGVIEIVSGASRGIRLLQEEEEGLPLVGRVAAGEPLLAQQHIEGHYQVDPSLFKPNADFLLRVSGMSMKDIGIMDGDLLAVHKTQDVRNGQVVVARIDDEVTVKRLKKQGNKVELLPENSEFKPIVVDLRQQSFTIEGLAVGVIRNGDWL
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: HELS_THEKO
Sequence: MKVDELPIDERIKRVIKERGIEELYPPQAEALKSGVLEGKNLVLAIPTASGKTLVSEIVMVNKLLSEGGKAVYLVPLKALAEEKYREFKEWEVLGLRVAATTGDYDSTDEWLGRYDIIVATAEKFDSLLRHGASWIKDVKLVVADEVHLIGSYDRGATLEMILTHMLGKAQILALSATVGNAEELAEWLDASLVVSDWRPVELRKGVFHLGQLFWEDGKIDHYPENWESLVLDAVKKGKQALVFVNTRRSAEKEAISLSSKVSKLLTKPETRRLEELISSIEDNPTTEKLKRALKGGVAFHHAGLSRAERTLIEDAFRNGLIKVITATPTLCMHPDTYVVTKSGAKKVSELTEGDEVLTHTGTFKKVIQPLRREHKGRLLVIKAYGTVPVKITPEHMVWVVKQIRHKSHYSDGRQVIWWEFEGPEWMTAQELKERLESETDPKVSYMLLQPIPEPSVDADKIPLRKEVYVVNQHGKTDKLHPSVKRTPEYLPLNFETARLIGLWIAEGSTSKNGVIKFDISSNEEDLTEFITGTIRKYFPHAKIVVKDHERNRRTVRFCNKRFAEWLRENIGHGADNKSIPPLLLLNKNREVRLGLLRGLIEGDGYVRRESQRRANYISYSTVSPSLAYQLQLLVASLGYTSSIHRSIRTEGIGKTRKPIYDVKVSGKSYYSLLEELGFEVPQRGNRTYNVNRTWKNYLLLKVRSIEEEEYEGDVYNLEVEGDESYSVGFIVHNSAGINLPAFRVIIRDTKRYANFGWTDIPVLEIQQMMGRAGRPKYDKVGEAIIVARTEDPKKLIDRYIHGKPEKLFSMLANEQAFRSQVLALITNFGVEDFRELVDFLSRTFYAHQRGDTSSLEYKAKDIVYFLIENEFIDMDVENRFIALPFGRRTSQLYIDPLTAKKFKDAFPAIERNPNPFGIFQLLASTPDMATLTARRREMEDYLDLAYEMEEHLYSSIPYYEDSRFQGFLGQVKTAKVLLDWINEVPEARIYETYNIDPGDLYRILELADWLMYSLIELYKLFEPKEDVLQYLRDLHLRLRHGVREELLELVKLPNIGRRRARALYNAGFRSVEDILRAKPKDLLQVEGIGLKIIEGIYRHLGVEYTISEKEKPKKRKGNLYDFLK
What is the function of this protein?
DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
What are the official names of this protein?
ATP-dependent DNA helicase Hel308, ATP-dependent Holliday junction unwindase Hjm.
What is the protein family that this protein belongs to?
Belongs to the helicase family. Hel308 subfamily.
Protein: RL10_BRUC2
Sequence: MDRAEKREFVAWLNGAFKESGSVVVAHYTGLTVAQMSDLRSKMRDAGGSVKVAKNRLAKIALQGTESEGIADLFTGQTVVAYANDPITAPKVAVEFAKANDKLVILGGAMGATTLNADGVKSLASLPSLDELRAKLVGMIQTPAQRLAVLTSAPAGQIARVIGAHARKNEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: ENO12_SCHPO
Sequence: MTTIQKIYSRSIYDSRGNPTVEVELTTELGTFRSMVPSGASTGEWEAKELRDNDKNKWGGKGVTIAVHNVNNIIGPALVKSDIKITDQRGIDEFMIKLDGTNDKSKLGANSIVGVSMAVARAAAAFLKIPLYEYIGKLAGSKTTECIPVPSFNVLNGGRHAGGDLAFQEFMIMPIKAPTFSEGLRWGSEVYHTLKALAKKKYGASAGNVGDEGGIAPDLTTAEEALDLVNEAIKEAGYDGKVKIGFDVAASELYNGKLYDLDFKSEHPKPENKLDYKKLYEKYSALIEKYPIVFIEDPFSEEDWGAFSYMSSKTKVEVIADDLTVTNVKRLSKAIELKCANALLVKINQIGSLSETIDAANMAKKAGWGLMVSHRSGETDDSFIAHLAVGLEAGQMKSGAPCRSERLAKYNELLRIEDNLGDSAIYAGTRAADYIKSNTL
What are the official names of this protein?
Enolase 1-2, 2-phospho-D-glycerate hydro-lyase 1-2, 2-phosphoglycerate dehydratase 1-2.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MFR7_PHOSM
Sequence: MTKPFILLVPGSFAPETIYASTIAHLRTLGFPAVALRLPTTTKRMPLPAATMAEDADVIKRSVEAVLATGQEVVVVCHSYGGTPTTQALGELGEKKGVRRVVYLSAIIPRVGESNNDAMGGKKGELAFEMTEGYMHIDATTFAPAVCNDLSWDLAYEHTLNLAHHSGASFLEPATQAGYLDIPVSYIFCEKDMVVTPEKQSGFIDVVKEATGKEVHVVKLDAGHCPNWSMPEKLGDVIAEMAGM
What is the function of this protein?
Probable hydrolase; part of the gene cluster that mediates the biosynthesis of squalestatin S1 (SQS1, also known as zaragozic acid A), a lead compound for the treatment of hyper-cholesterolemia by targeting squalene synthase (SS) (PubMed:27056201).  Both phenylalanine and benzoic acid are known precursors of SQS1 and so it is unsurprising that the cluster also contains genes potentially involved in benzoate production such as phenyl-alanine ammonia lysase (PAL) M7, which catalyzes the first step in the degradation of phenylalanine, or the NADP-dependent dehydrogenase M3 (PubMed:27056201).  The cluster contains two PKS encoding genes.  The tetraketide synthase is responsible for the biosynthesis of the tetraketide sidechain of SQS1 (By similarity).  The biosynthesis must involve 3 rounds of chain extension.  After the first and second rounds methyl-transfer occurs, and in all rounds of extension the ketoreductase and dehydratase areactive.  The enoyl reductase and C-MeT are not active in the final round of extension (By similarity).  The other PKS is therefore likely to encode squalestatin hexaketide synthase (SQHKS) (PubMed:27056201).  The hexaketide main chain is initiated by benzoate which is an unusual starter unit for a highly reducing polyketide synthase (PubMed:27056201).  The cluster also contains a gene encoding a citrate synthase-like protein R3 presumably involved in linking the hexaketide to the oxaloacetate moiety (Probable).  Formation of the tetraketide CoA may be catalyzed by the M9 CoA ligase, but the mechanism of release of the tetraketide and the hexaketide from their respective PKS remains unknown, although the cluster encodes a potential esterase (M8) and a possible hydrolase (M10) which could be involved in these processes (Probable).  Two acyltransferases (AT), M4 and R4, are also encoded in the cluster.  M4 is responsible for loading of the tetraketide sidechain from CoA onto the squalestatin core as the final step of biosynthesis (PubMed:27056201).  M4 appears to have a broad substrate selectivity for its acyl CoA substrate, allowing the in vitro synthesis of novel squalestatins (PubMed:27056201).  The biosynthesis of SQS1 requires several oxidative steps likely performed by oxidoreductases M1, R1 and R2 (Probable).  Finally, in support of the identification of the cluster as being responsible for SQS1 production, the cluster contains a gene encoding a putative squalene synthase (SS) R6, suggesting a likely mechanism for self-resistance (PubMed:27056201).
What are the official names of this protein?
Probable hydrolase R7, Squalestatin S1 biosynthesis cluster protein R7.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
Protein: MBOA7_XENLA
Sequence: MSPNELTYLAILLGSAPLGFLFKNGSPQVKQRGSAAVGVALTLITCHIHSLHSAITILGTWLIIKILPRSCHFPTLGWTFTYLLFFRTITYFDIPAPTPFTNAVQLLLTLKLVSLANEVQDFYRAKKQEVTSFSKPSAISTIPSIPSLREMFYYSYCYIGLMTGPFYRYKTYYDWLHQIDPASIPSWKPLVSRLKPAPVFGVLFLIASQYFPLDYVKTDEFYEQAFLYRLFYMVPTFFIFRMRFYVAWIFAECGCISAAFGAYPVSAKSRSGGGPTVEYAPLERNAEGAKVELEYDYETIKNIDCYGADFCVKVKDGMRYWNMSVQWWLAQYIYKNSPVKSLVFGSAWTMLVSAYWHGIHPGYYMSFLTIPLCLAAEGSMEAGLRRHVSDSGKMIFDWVHWFLKMRAYDYMCMGFVLLTFTDTYRYWQSIYFSVHVLAISLFLLGRVLALKSPRRPRNTKEEKAEAKQENRLQE
What is the function of this protein?
Acyltransferase which catalyzes the transfert of an acyl group from an acyl-CoA to a lysophosphatidylinositol (1-acylglycerophosphatidylinositol or LPI) leading to the production of a phosphatidylinositol (1,2-diacyl-sn-glycero-3-phosphoinositol or PI) and participates in the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle.  Prefers arachidonoyl-CoA as the acyl donor, thus contributing to the regulation of free levels arachidonic acid in cell.
What are the official names of this protein?
Lysophospholipid acyltransferase 7, LPLAT 7, Leukocyte receptor cluster member 4, Membrane-bound O-acyltransferase domain-containing protein 7, O-acyltransferase domain-containing protein 7.
What is the protein family that this protein belongs to?
Belongs to the membrane-bound acyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: TSC10_DEBHA
Sequence: MLFSNNKIHAEGKLALIVGASQGLGADLALKLYQQNCSVILVARTETKLVAQIERIQSSSPENNATLSYKCCDASNYEDCVKLWNDLIVDQKQDPDFIFCCAGSSIPKLFSDLTAKDFAIGINTNYTTSLNITHTGFKQVLGQFSDLSCDQYKKRHVIFVSSVVSFYPFIGYSQYAPLKSAIQSLSIILRQEMGPFNYRVSCVFPGNFQSEGYEEEQKTKPSITKSIEGSSKPISGEDCADIILNQLNRGYDTVTTDFIGWLLGCSVLGVLPRSWGFFQVIVSFIFSIIAPIANYVVYRDVLKFFKTRSTREVEEYEIVSTDDNKKTL
What is the function of this protein?
Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).
What are the official names of this protein?
3-ketodihydrosphingosine reductase TSC10, 3-dehydrosphinganine reductase, KDS reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: LHG_BLAVI
Sequence: YFAADGSVVPSISDWNLWVPLGILGIPTIWIALTYR
What is the function of this protein?
One of the components of the bacteriochlorophyll-protein complex in the chromatophore membrane.
What are the official names of this protein?
Light-harvesting protein B-1015 gamma chain.
Protein: NUSG_STAAE
Sequence: MSEEVGAKRWYAVHTYSGYENKVKKNLEKRVESMNMTEQIFRVVIPEEEETQVKDGKAKTTVKKTFPGYVLVELIMTDESWYVVRNTPGVTGFVGSAGAGSKPNPLLPEEVRFILKQMGLKEKTIDVELEVGEQVRIKSGPFANQVGEVQEIETDKFKLTVLVDMFGRETPVEVEFDQIEKL
What is the function of this protein?
Participates in transcription elongation, termination and antitermination.
What are the official names of this protein?
Transcription termination/antitermination protein NusG.
What is the protein family that this protein belongs to?
Belongs to the NusG family.
Protein: CYB_NAJMU
Sequence: MSNQHTLLVSNLLPVGSNISTWWNFGSMLLTCLALQTMTGFFLAIHYTANINLAFSSVIHITRDVPYGWIMQNIHAISASLFFICIYIHIARGLYYGLYLNKEVWLSGTTLLITLMATAFFGYVLPWGQMSFWAATVITNLLTAIPYLGATLTTWLWGGFSINDPTLTRFFALHFILPFAIISLSSIHIILLHNEGSNNPLGTNSDIDKIPFHPYHSYKDMLMITSMITLLFIILSFSPNLLNDPENFSKANPLVTPQHIKPEWYFLFAYGILRSIPNKLGGTLALLTSVAILTTVPFTHTSYTRSMMFRPLSQALFWTLIATFITITWTASKPVEPPFVTISQTTSIIYFSFFITIPLLGWAENKMMMMNN
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SYC_BUCA5
Sequence: MLKIFNTLTSTKEIFTPIKKNRVNLYVCGVTVYDFCHIGHGRTFVVFDMIVRYLRFSGFQVKYVRNITDIDDKIISKSTKEKKKINTFTASMIKEMHKDFDLLGISVPDEEPRVTDYIDNIIRIITTLIKKKHAYIHKNGDVIFSIDSDPNYGTLSRQSLTSLESGSRIPLNNMKKNPLDFILWKSSNKEEYSWDSPWGKGRPGWHIECTAITNVFFNNSIDIHGGGSDLLFPHHENERSQSICFNNKSMINFWMHTGMVILNNKKMSKSLGNVYFLRNILKDCDAEVLRYFFLSTHYRHPIYYCEKNLDQAYTSLKYLYTALYDTNPFFNNEEGLNFELEFYNAMNDDFNTPAVFSIFFKIARKINFLKNKDILKTNKFAFRLKYLANNLGFLFQDPKEFLQKKTTLNLLTLKEIQLLIEKRNIARQSKLWQEADNIRKKLMSLDIILEDLPDKTIWRKNKKS
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LCL2_TALMQ
Sequence: MLAKPLTAIWTLFLLISTAQAQFQFFEQMFGGGGSHQGHQQEQEASSDSSWYQQTWEGTHCTKYLCPDTLACVHFPHHCPCPHPSVEEKVELGEGSAVCVSRGGWTAGEAARKIELARKGVL
What is the function of this protein?
Probable component of the endoplasmic reticulum-associated degradation (ERAD) pathway.
What are the official names of this protein?
Long chronological lifespan protein 2.
What is the protein family that this protein belongs to?
Belongs to the LCL2 family.
Protein: ZFTA_HUMAN
Sequence: MEPGGDHRSRSSGGRGGPGPAVASARGRRLPPAGSSGSAEPEEDEGGQDLQLEGGALGSWGSAPLPSSRARGPASSGRKYSDHCEARASRPGKSRIPGRDHRRYYHDHWRLEYLMDFNPARHGMVCMVCGSSLATLKLSTIKRHIRQKHPYSLHWSPREKEVISNSWDAHLGLGACGEAEGLGVQGAEEEEEEEEEEEEEGAGVPACPPKGPGKAPAGGGCRRQRRGGPVAPRARRLRLSASRRAGGSRGLGARRLERRLKESLQNWFRAECLMDYDPRGNRLVCMACGRALPSLHLDDIRAHVLEVHPGSLGLSGPQRSALLQAWGGQPEALSELTQSPPGDDLAPQDLTGKSRDSASAAGAPSSQDLSPPDVKEEAGWVPERPGPAEEEEELEEGEGERAGVPGRSPRGRAHRRHPQERWRLEYLMELDGGRRGLVCGVCGGALASLKMSTIERHIRRRHPGSTRLGGPVQALIAREWSEKAAHLLALGPPRPESPQGPIPPGTAAASDEGGGDEEEEPEEEEEEWGDVPLSPGAPLERPAEEEEDEEDGQEPGGLALPPPPPPPPPPPPRSREQRRNYQPRWRGEYLMDYDGSRRGLVCMVCGGALATLKVSTIKRHILQVHPFSMDFTPEERQTILEAYEEAALRCYGHEGFGPPAPAPRDGGADLKSGAVCRA
What are the official names of this protein?
Zinc finger translocation-associated protein, ZFTA.
Protein: YGIB_ECO57
Sequence: MKRTKSIRHASFRKNWSARHLTPVALAVATVFMLAGCEKSDETVSLYQNADDCSAANPGKSAECTTAYNNALKEAERTAPKYATREDCVAEFGEGQCQQAPAQAGMAPENQAQAQQSSGSFWMPLMAGYMMGRLMGGGAGFAQQPLFSSKNPASPAYGKYTDATGKNYGAAQPGRTMTVPKTAMAPKPATTTTVTRGGFGESVAKQSTMQRSATGTSSRSMGG
What are the official names of this protein?
UPF0441 protein YgiB.
What is the protein family that this protein belongs to?
Belongs to the UPF0441 family.
Protein: CLPS_SHEHH
Sequence: MSRTENIEQIEESVEAEFKQPSMYKVILNNDDYTPMDFVIEILQLFFKKDEQQATEIMLAIHHKGKGICGIYPFGIAETKVAQVNQFARQNQHPLLCSLEEA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: EX7S_NITHX
Sequence: MAENALADVKTLSFERAIEELESIVKRLEDGKVPLEESVAIYERGEALKRRCEELLRQAEARVEKITTDASGQVTGTEPLDVQ
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.