PharMolix/UniProtQA huggingface dataset:
Protein: ECHP_HUMAN
Sequence: MAEYTRLHNALALIRLRNPPVNAISTTLLRDIKEGLQKAVIDHTIKAIVICGAEGKFSAGADIRGFSAPRTFGLTLGHVVDEIQRNEKPVVAAIQGMAFGGGLELALGCHYRIAHAEAQVGLPEVTLGLLPGARGTQLLPRLTGVPAALDLITSGRRILADEALKLGILDKVVNSDPVEEAIRFAQRVSDQPLESRRLCNKPIQSLPNMDSIFSEALLKMRRQHPGCLAQEACVRAVQAAVQYPYEVGIKKEEELFLYLLQSGQARALQYAFFAERKANKWSTPSGASWKTASARPVSSVGVVGLGTMGRGIVISFARARIPVIAVDSDKNQLATANKMITSVLEKEASKMQQSGHPWSGPKPRLTSSVKELGGVDLVIEAVFEEMSLKKQVFAELSAVCKPEAFLCTNTSALDVDEIASSTDRPHLVIGTHFFSPAHVMKLLEVIPSQYSSPTTIATVMNLSKKIKKIGVVVGNCFGFVGNRMLNPYYNQAYFLLEEGSKPEEVDQVLEEFGFKMGPFRVSDLAGLDVGWKSRKGQGLTGPTLLPGTPARKRGNRRYCPIPDVLCELGRFGQKTGKGWYQYDKPLGRIHKPDPWLSKFLSRYRKTHHIEPRTISQDEILERCLYSLINEAFRILGEGIAASPEHIDVVYLHGYGWPRHKGGPMFYASTVGLPTVLEKLQKYYRQNPDIPQLEPSDYLKKLASQGNPPLKEWQSLAGSPSSKL
What is the function of this protein?
Peroxisomal trifunctional enzyme possessing 2-enoyl-CoA hydratase, 3-hydroxyacyl-CoA dehydrogenase, and delta 3, delta 2-enoyl-CoA isomerase activities.  Catalyzes two of the four reactions of the long chain fatty acids peroxisomal beta-oxidation pathway (By similarity).  Can also use branched-chain fatty acids such as 2-methyl-2E-butenoyl-CoA as a substrate, which is hydrated into (2S,3S)-3-hydroxy-2-methylbutanoyl-CoA (By similarity).  Optimal isomerase for 2,5 double bonds into 3,5 form isomerization in a range of enoyl-CoA species (Probable).  Also able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species (By similarity).  With HSD17B4, catalyzes the hydration of trans-2-enoyl-CoA and the dehydrogenation of 3-hydroxyacyl-CoA, but with opposite chiral specificity (PubMed:15060085).  Regulates the amount of medium-chain dicarboxylic fatty acids which are essential regulators of all fatty acid oxidation pathways (By similarity).  Also involved in the degradation of long-chain dicarboxylic acids through peroxisomal beta-oxidation (PubMed:15060085).
What are the official names of this protein?
Peroxisomal bifunctional enzyme, PBE, PBFE, L-bifunctional protein, LBP, Multifunctional enzyme 1, MFE1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: PLSY_ECOUT
Sequence: MSAIAPGMILIAYLCGSISSAILVCRLCGLPDPRTSGSGNPGATNVLRIGGKGAAVAVLIFDVLKGMLPVWGAYELGVSPFWLGLIAIAACLGHIWPVFFGFKGGKGVATAFGAIAPIGWDLTGVMAGTWLLTVLLSGYSSLGAIVSALIAPFYVWWFKPQFTFPVSMLSCLILLRHHDNIQRLWRRQETKIWTKFKRKREKDPE
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-ACP to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme can also utilize acyl-CoA as fatty acyl donor, but not acyl-PO(4).
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ETFA_CRYGW
Sequence: MLYRSALRTSRAFTPRLALSHSRLVSSLVFLEHKAGKLSEASLSAVTAAKTLGNDTHGLLVGTKSEIENALDRAKEIKGLSKIYLARSDSYSHSLAEALASLLASIVSAKDVSHLFAAHTAVGKNVFPRLAGLLDSSLIADIIALESSGDTFTRPIYAGNAVLTIKSSPKDSVKIVTVRSTAFDKAPVAAGSAVIEDVDIITVDTPTQFVSEELTVSSRPDLASAARVVSGGRALKSKESFDAILNPLADSLGAAVGASRAAVDAGYADNSLQVGQTGKVVAPELYVAIGISGAIQHLAGMKESKMIIAINKDPDAPIFQVADVGLVADLFESVPQLVKELGNVKV
What is the function of this protein?
The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase.  It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity).
What are the official names of this protein?
Probable electron transfer flavoprotein subunit alpha, mitochondrial, Alpha-ETF.
What is the protein family that this protein belongs to?
Belongs to the ETF alpha-subunit/FixB family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: SNMP1_DROSI
Sequence: MQVPRVKLLMGSGAMFVFAIIYGWVIFPKILKFMISKQVTLKPGSDVRELWSNTPFPLHFYIYVFNVTNPDEVSEGAKPRLQEVGPFVFDEWKDKYDLEDDVVEDTVSFTMRNTFIFNPKESLPLTGEEEIILPHPIMLPGGISVQREKAAMMELVSKGLSIVFPNAKAFLKAKFMDLFFRGINVDCSSEEFSAKALCTVFYTGEVKQAKQVNQTHFLFSFMGQANHSDSGRFTVCRGVKNNKKLGKVVKFADEPEQDIWPDGECNNFVGTDSTVFAPGLKKEDGLWAFTPDLCRSLGAYYQHKSSYHGMPSMRYTLDLGDIRADEKLHCFCEDPEDLDTCPPKGTMNLAACVGGPLMASMPHFYLGDPKLVADVDGLNPNEKDHAVYIDFELMSGTPFQAAKRLQFNLDMESVEGIEPMKNLPKLILPMFWVEEGVQLNKTYTNLVKYTLFLGLKINSVLRWSLITFSLVGLMFSAYLFYHKSDSLDINSILKDNNKVDDVASTKEPMPPANPKQSSTVHPVQLPNTLIPGTNPATNPATHLKMEHRERY
What is the function of this protein?
Plays an olfactory role that is not restricted to pheromone sensitivity.
What are the official names of this protein?
Sensory neuron membrane protein 1.
What is the protein family that this protein belongs to?
Belongs to the CD36 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CSRA_XANOR
Sequence: MLILTRRVGETLMIGDSVTVTVLGVKGNQVRIGITAPKDVAVHREEIYQRIQRGDEPVASGAHHGDDSSN
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXB_ECOL6
Sequence: MKILVDENMPYARDLFSRLGEVTAVPGRPIPVAQLADADALMVRSVTKVNESLLAGKPIKFVGTATAGTDHVDEAWLKQAGIGFSAAPGCNAIAVVEYVFSSLLMLAERDGFSLHERTVGIVGVGNVGRRLQARLEALGIKTLLCDPPRADRGDEGDFRSLDELVQHADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLTCLNEGQKLSVVLDVWEGEPELNVELLKKVDIGTPHIAGYTLEGKARGTTQVFEAYSKFIGHEQHVALDTLLPAPEFGRITLHGPLDQPTLKRLVHLVYDVRRDDAPLRKVAGIPGEFDKLRKNYLERREWSSLYVICDDASAASLLCKLGFNAVHHPAR
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FSHR_MOUSE
Sequence: MALLLVSLLAFLGSGSGCHHWLCHCSNRVFLCQDSKVTEIPPDLPRNAIELRFVLTKLRVIPKGSFSGFGDLEKIEISQNDVLEVIEADVFSNLPNLHEIRIEKANNLLYINPEAFQNLPSLRYLLISNTGIKHLPAFHKIQSLQKVLLDIQDNINIHIIARNSFMGLSFESVILWLNKNGIQEIHNCAFNGTQLDELNLSDNNNLEELPDDVFQGASGPVVLDISRTKVYSLPNHGLENLKKLRARSTYRLKKLPSLDKFVMLIEASLTYPSHCCAFANWRRQTSELHPICNKSISRQDIDDMTQPGDQRVSLVDDEPSYGKGSDMLYSEFDYDLCNEFVDVTCSPKPDAFNPCEDIMGYNILRVLIWFISILAITGNTTVLVVLTTSQYKLTVPRFLMCNLAFADLCIGIYLLLIASVDIHTKSQYHNYAIDWQTGAGCDAAGFFTVFASELSVYTLAAITLERWHTITHAMQLECKVQLCHAASIMVLGWAFAFAAALFPIFGISSYMKVSICLPMDIDSPLSQLYVMALLVLNALAFVVICGCYTHIYLTVRNPNIVSSSRDTKIAKRMATLIFTDFLCMAPILFFAISASLKVPLITVSKAKILLVLFYPINSCANPFLYAIFTKNFRRDFFVLMSKFGCYEVQAQIYKTETSSITHNFHSRKNPCSSAPRVTNSYVLVPLNHSVQN
What is the function of this protein?
G protein-coupled receptor for follitropin, the follicle-stimulating hormone.  Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.
What are the official names of this protein?
Follicle-stimulating hormone receptor, FSH-R, Follitropin receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL33_CHLPM
Sequence: MAKGKENRIVITLECTEAKKEGKTVSRYTTTKNKKNTTDRLVLKKYNPSMQKHTLHKEIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: AROK_STAAW
Sequence: MNHDKSPIILIGFMGTGKSTIGKYVADEQNLSFIDIDSYIEEKYKLTIPEIFSKHGEQYFRNLEFTCLQECINTADIIATGGGIIESEEAFNFLKNQKNIIWLDCNIDIIYSRINDDPHRPNANNKTIKQLNDLYCSRNLRYNEIAFKKFDSHLLSISEIYYELLNLIKASDQY
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCD22_XENTR
Sequence: MEEVDRILIHSLRSCGTEVPEDVQSIRQFNTELIVEAVVRCLRVINPSLGATLSHVLPPGMSARFRIGTSLAQACQDLGYPGEVGYQTFLYSSEPDIRALLIFLAEKLPRDSPEDAHQPAGKSALLQREIAATIKRQLSLPWLPSSCRICALRRSQNSCRLHRFHAQPLSLATDPTLKSIPDERKEYWQCYLPSVTSQLPHLPSVAASLLERNTSELSAKQEWDAEWKSQGLASRLSPEDYRSRKRQRLQKRIQEQLRQCAQLLAENHLPSSSSQDLTDMLKAFNLDGGSDQKKGSRFTRTQRFTYQQDPHTLKEQMQRAAEILPKKDAQDTDAEQQELSSLQEQIDSIEQEIRGLSESNKRLQLTVSQVEGEVNEMRQSCEEKEKIVRVKKRAVELLPDADNNLVKLQALVDASSHRMANLVGQWESHQVRLSEEYRELKRVQQEQEDESSRWMKDAKDLYEKIRGAADEAKRKEELYKQLLSEYESLPKEVSRAAYTQRILEIVSNIKKQKEEITKILSDTKELQKEINNLTGKVDRTFVVTDELVFKDAKKDEPVRKAYKYLAALHENCSQLIQTIEDTGTILREIRDLEEQIETETTKKTLSNLQKILEDYRAIKQENAQLLARIREA
What is the function of this protein?
May be involved in regulation of NF-kappa-B signaling.  May be involved in copper-dependent atp7a trafficking between the trans-Golgi network and vesicles in the cell periphery (By similarity).
What are the official names of this protein?
Coiled-coil domain-containing protein 22.
What is the protein family that this protein belongs to?
Belongs to the CCDC22 family.
Protein: CT11_CONLE
Sequence: MRCLPVFIILLLLIPSAPSVDAQPKTEDDVPLASLHDNAKLTLQGLWDKRCCPNLFYCCPDRRK
What are the official names of this protein?
Conotoxin Leo-T1.
What is the protein family that this protein belongs to?
Belongs to the conotoxin T superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NDHO_PROM9
Sequence: MTDSIPKKPLKKGSLVFVDRGNYIKSIEALASDNDLPNYVFEGPGEILSVKDEYAQVRWRRPVPDVWFKLDQLKEYIQ
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit O, NAD(P)H dehydrogenase I subunit O, NDH-1 subunit O, NDH-O.
What is the protein family that this protein belongs to?
Belongs to the complex I NdhO subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PSD_CHLAB
Sequence: MKKLQYIDRLTNQRVTESVCYEKTMTFLYSSKLGKRLSTLLSRSPILSRIYGWIQKRSWTRRKIPGFVKRNHINIKDFKKSLSEFSSFNDFFTRELLPEARPIAQGDNICVTPVDGAYLIYSNIAEFGEFVVKSKRFSLSKLLGDPRLVEKYASGSVVFARLALFDYHRFHFPVDCLPGPTRTINGYLFSVHPMALKDNFNIFCENKRTLTELKTEAFGDVLYLEVGALNVGSIIQTYKPGEKYSKGDEKGFFEIGGSTVIVLFQPGSVQFDADLLKNSRMGLETRCLMGQSLGRSLRE
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type II sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: REQ1_ECOLI
Sequence: MRDIQMVLERWGAWAANNHEDVTWSSIAAGFKGLITSKVKSRPQCCDDDAMIICGCMARLKKNNSDLHDLLVDYYVVGMTFMSLAGKHCCSDGYIGKRLQKAEGIIEGMLMALDIRLEMDIVVNNSN
What is the function of this protein?
Positively regulate expression of some phage genes.  Bacterial host RNA polymerase modified by antitermination proteins transcribes through termination sites that otherwise prevent expression of the regulated genes (By similarity).
What are the official names of this protein?
Prophage antitermination protein Q homolog QuuD, Antitermination protein Q homolog from lambdoid prophage DLP12.
What is the protein family that this protein belongs to?
Belongs to the phage antitermination Q type 1 family.
Protein: IPYR_LEPIN
Sequence: MVHPWHDISPGDQNPEIVNGVIEIKRGSRAKYEVDKEYGILKLDRVLYSSFYYPANYGFIPQSYCGDQDPLDILVLSQVELEPLCLVKAKVIGVMRMLDSGEEDDKIIAVAANDMSVNHINDISELPPHFTLELKHFFEDYKKLENKTVVIEEFQNAILARKIVLDSLELYKKTFPKK
What is the function of this protein?
Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
What are the official names of this protein?
Inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLNR_BACAN
Sequence: MKEDRRSAPLFPIGIVMDLTQLSARQIRYYEEHNLVSPTRTKGNRRLFSFNDVDKLLEIKDLLDQGLNMAGIKQVLLMKENQTEAVKVKEETKEISKTELRKILRDELQHTGRFNRTSLRQGDISRFFH
What is the function of this protein?
Transcription repressor during nitrogen excess.  On the contrary of the MerR members, which require longer DNA sites for high-affinity binding, GlnR requires a DNA sequence of 17 nucleotides as minimal binding site.
What are the official names of this protein?
HTH-type transcriptional regulator GlnR.
Protein: RNY_CARHZ
Sequence: MNLITDIIIAVAGVGVGVAAGYVIRKNIAEAAIGSAEAQAKKIIDEATKAAEAKKREAVLEAKEEILKMKNEVEREHRERRQELQRLERRLLSKEETLDRKIESFERKEEQLAKKEQEIENLRQSLEETLQKELAELERISGLSTEEARELLLKQVEEEVQQEMALLIKEIETKAKEEAEKRAREIITLAIQRCAADHAAETTVTVVALPNDEMKGRIIGREGRNIRTFESLTGVDLIIDDTPEAVILSGFDPIRREIARRALEKLIQDGRIHPARIEEMVERATKEVEQDIREAGEQAAFEVNVHGLHPEIIKLLGRLKFRTSYGQNILKHSIEVAHLAGLMAAELGADVALAKRAGLLHDIGKAVDHEVEGSHVEIGVELAKKYREHPEVLHAIATHHGDEEPKTVEAVLVQAADAISAARPGARRETLEAYLKRLEKLEGIANEFEGVEKSYAIQAGRELRILVKPEKIDDLASVRLAREIAKKIEEEVEYPGQIKVTVIRETRAVDYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: CWLM_BACLI
Sequence: MVKIFIDPGHGGSDTGASANGLQEKQLTLQTALALRNMLLNEYQNVSVLLSRTSDQTVSLTQRTNAANSWGADYFLSIHMNAGGGTGFEDYIYPGVGAPTTTYRDIMHEEILKVVDFRDRGKKTANFHVLRETAMPALLTENGFVDNTNDAEKLKSSAFIQSIARGHANGLARAFNLSKNAAALYKVQIAAFRTKANADSLAAQAEAKGFDALVIYRDSLYKVQIGAFSSKENAEALVQQAKNAEFDTFIYQE
What is the function of this protein?
Hydrolyzes the cell wall of M. luteus more efficiently than that of B. licheniformis and B. subtilis.  The C-terminal region, including the repeats, determines substrate specificity.
What are the official names of this protein?
N-acetylmuramoyl-L-alanine amidase CwlM, Autolysin, Cell wall hydrolase.
What is the protein family that this protein belongs to?
Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family.
What are the subcellular locations of this protein?
Secreted. Note=Accumulates in cells as inclusion bodies. May be secreted by a mechanism different from the normal export system.
Protein: EGLC_ASPOR
Sequence: MQLTHLLAFALSLATSEAAYKGFNYGATKSDGSVKSQSDFESEFSTAKNLVGTSGFTSARLYTMIQGGTTNSPISAIPAAIAENTSLLLGLWASGGGMDNELAALKSAISQYGDSFAKLVVGISVGSEDLYRASSEGEKVNAGIGIGPDDLVSFIKEVRSIISGTALSSVPIGHVDTWTAWTNGSNSAVIDAVDWLGFDGYPYFQSSMSNSISDAKSLFDDSVAKTKAVAKGKEVWITETGWPVSGSTQNLGVASLANAKTYWDEVGCPLFDETNTWWYILQDANPTTPNPSFGVVGSTLSTTPLFDLSCSNSTRPSASASSSAAGSATPVGSAVPSGSAAVNPSSSGIVSSAVPSTTPGFTVGKGFRPSNSSAAAYYSSASASGSAYPKFTKTASGSSATSTTAGSSSDSSSTNSGKSSSESSSTNSGASASSSILATGGASSVSGSVFGALVAVFAFVATL
What is the function of this protein?
Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation.  This enzyme may be involved in beta-glucan degradation and also function biosynthetically as a transglycosylase (By similarity).
What are the official names of this protein?
Probable glucan endo-1,3-beta-glucosidase eglC, Endo-1,3-beta-glucanase eglC, Laminarinase eglC.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 17 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor. Secreted, cell wall. Note=Covalently-linked GPI-modified cell wall protein.
Protein: PNP_HELPS
Sequence: MDFITITSSNKTEEFALKQVAKQATSSLMYRLGKTIILASVCVEREPVGEDFLPLVVQFLEKSYAAGKIPGGFVKREGRAQDFEILTSRLIDRTLRPLFPKDYRYPTQITLMVLSHDVENDLQVSALNAASAALFLSHIAPIKSVSACRIARIGNEFIINPNTSLLNQSSLDLFVSGTKESLNMIEMRSLGQQLNALEEPLMLKALELAQKSLKETCTLYEEIFTPHQNELLFKESQGIIFNERLLDLLKNQYFDEIIKGIESSALSERENVFNEIARKISEAHSEFSLKEIELSLEKVKKTEIRCMIIKDKIRPDKRALEEVRPILIESDLLPMAHSSILFTRGQTQSLVVGVLGTDNDAQTHESLEHKAPIKERFMFHYNFPPFCVGEASSIGATSRRELGHGNLAKRALETSIKNKDQVIRLVSEILESNGSSSMASVCAGSLALYASGVEIYDLIAGVAMGMVSEGQDHAILSDISGLEDAEGDMDFKIAGNLEGITAMQMDTKMSGIQLEVLYQALLQAKKAREHILKIMHEAKEKIVINFSHLPTTEIFNVAPDKIVEIIGQGGRVIREIVEKFEVKIDLNKPSGEVKIMGNKERVLKTKEFILNYLHSLDQELEQYAIDEVLEAQVKRIVDFGAFLSLPKGGEGLLRKQNMDRCQVVLKEGDSIKCRVISFNKGKIALDLA
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_STACT
Sequence: MKVRPSVKPICEKCKVIKRKGKVMIICENPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: YOPT1_YERE8
Sequence: MDSIHGHYHIQLSNYSAGENLQSATPPEGVIGAHRVKVETALSHSNRQKKLSATIKHNQSSRSMLDRKLTSDGKVNQRSSFTFSMIMYRMIHFVLSTRVPAVRESVANYGGNINFKFAQTKGAFLHQIIKHSDTARGACEALCAHWIRSHAQGQSLFDQLYVGGRKGKFQIDTLYSIKQLQIDGCKADVDQDEVTLDWLKKNGISERMIERHCLLPTVDVTGTTGSEGPDQLLNAILDTNGIGYGYKKISLSGQMSGHTIAAYVNENSGVTFFDPNFGEFHFSDKEKFSKWFTNSFWENSMYHYPLGVGQSFSVFTFDSKEV
What is the function of this protein?
Cysteine protease, which is translocated into infected cells and plays a central role in pathogenesis by cleaving the C-terminus end of the human small GTPase RhoA/ARHA, a regulator of cytoskeleton.  Once cleaved, ARHA loses its lipid modification, and is released from the cell membrane, leading to the subsequent disruption of actin cytoskeleton of the host cell (By similarity).
What are the official names of this protein?
Cysteine protease yopT1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C58 family.
What are the subcellular locations of this protein?
Secreted. Note=In infected cells, it is cytoplasmic. Translocated into the host cell by the type III secretion apparatus with the help of the SycT chaperone (By similarity).
Protein: DEOD_ANOFW
Sequence: MSVHIGAKEHEIADKILLPGDPLRAKYIAETFLEGATCYNQVRGMLGFTGTYKGHRISVQGTGMGVPSISIYVTELMQSYNVQTLIRVGTCGAIQKDVKVRDVILAMTSSTDSQMNRMTFGGIDYAPTANFDLLKTAYEIGKEKGLQLKVGSVFTADMFYNENAQFEKLARYGVLAVEMETTALYTLAAKFGRKALSVLTVSDHILTGEETTAEERQTTFNEMIEVALETAIRQ
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: CTH1_CHLRE
Sequence: MATMLNKRVTGAFGKQAPVRSARVAAVRPSRSSVRVAATAAPQEVEGFKVMRDGIKVASDETLLTPRFYTTDFDEMERLFSLELNKNMDMEEFEAMLNEFKLDYNQRHFVRNETFKEAAEKIQGPTRKIFIEFLERSCTAEFSGFLLYKELGRRLKATNPVVAEIFTLMSRDEARHAGFLNKAMSDFNLALDLGFLTKNRKYTFFKPKFIFYATYLSEKIGYWRYISIYRHLQRNPDNQLYPLFEYFENWCQDENRHGDFFTAVLKARPEMVNDWAAKLWSRFFCLSVYITMYLNDHQRDAFYSSLGLNTTQFNQHVIIETNKSTERIFPAVPDVENPEFFRRMDLLVKYNAQLVNIGSMNLPSPIKAIMKAPILERMVAEVFQVFIMTPKESGSYDLDANKTALVY
What is the function of this protein?
Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis.  Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME).
What are the official names of this protein?
Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase 2, chloroplastic, Mg-protoporphyrin IX monomethyl ester oxidative cyclase 2, Copper target homolog 1 protein.
What is the protein family that this protein belongs to?
Belongs to the AcsF family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CPFC_STAS1
Sequence: MTKTIGLLVMAYGTPYKESDIEAYYTDIRHGKKPTEAELQDLKDRYQFIGGLSPLAGTTNRQAESLRDALNQAYDDVEFKLYIGLKHIHPFIEDAVQSMHEDGIDEAVTVVLAPHYSSFSVGSYNTRAQKEADKYGITFKHVEHYYQQPKFIQYWTEKINETLADIPQDEHDKTVLVVSAHSLPKGLIEKNNDPYPNELHETAQLLEQHSNIIHVAEGWQSEGNTGTPWLGPDVQDLTRALYNEHKYEHFIYTPVGFVCEHLEVLYDNDYECKVICDELGVHYHRPKMPDTDPLFIGAIVEEIKNVY
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
What are the official names of this protein?
Coproporphyrin III ferrochelatase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BRFL1_EBVA8
Sequence: MRPKKDGLEDFLRLTPEIKKQLGSLVSDYCNVLNKEFTAGSVEITLRSYKICKAFINEAKAHGREWGGLMATLNICNFWAILRNNRVRRRAENAGNDACSIACPIVMRYVLDHLIVVTDRFFIQAPSNRVMIPATIGTAMYKLLKHSRVRAYTYSKVLGVDRAAIMASGKQVVEHLNRMEKEGLLSSKFKAFCKWVFTYPVLEEMFQTMVSSKTGHLTDDVKDVRALIKTLPRASYSSHAGQRSYVSGVLPACLLSTKSKAVETPILVSGADRMDEELMGNDGGASHTEARYSESGQFHAFTDELESLPSPTMPLKPGAQSADCGDSSSSSSDSGNSDTEQSEREEARAEAPRLRAPKSRRTSRPNRGQTPCPSNAEEPEQPWIAAVHQESDERPIFPHPSKPTFLPPVKRKKGLRDSREGMFLPKPEAGSAISDVFEGREVCQPKRIRPFHPPGSPWANRPLPASLAPTPTGPVHEPVGSLTPAPVPRPLDPAPAVTPEASHLLEDPDEETSQAVKALREMADTVIPQKEEAAICGQMDLNHPPPRGHLDELTTTLESMTEDLNLDSPLTPELNEILDTFLNDECLLHAMHISTGLSIFDTSLF
What is the function of this protein?
Immediate-early transcription factor that controls the initiation of viral lytic gene expression and lytic reactivation from latency.  Triggers lytic replication, and initiates a cellular senescence program in epithelial cells.  Up-regulates human DCR3/TNFRSF6B by directly binding to its receptor.  Globally induces a proteasome-dependent loss of SUMOylated proteins in the host cell and the loss of promeylocytic leukemia nuclear bodies.  Improves the stability of the triplex capsid protein TRX1 by reducing the ubiquitination level of the latter.  Mediates evasion of inflammasome activation and antiviral responses (T- and NK cell activation) during EBV early lytic infection.
What are the official names of this protein?
Replication and transcription activator, Rta, Immediate-early protein Rta, Protein R.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae Rta family.
Protein: GLO2_METNO
Sequence: MPEIRTFLCRSDNIGVLLHDPVTSACAAIDVPEAGAVLRALKETGWRLTDILVTHRHFDHVEGIPEVKARTGARVTAPAKAGDAVPEVDATVREGDVVKVGSLVGTVWETPGHCADHVTYWFERERLAFAGDTLFTLGCGRVMESPPEVLWRSLSRFLALPDETAIYSGHDYVLSNARFALAADPDNSNLKARAELAERVKRDGRFLIPTTLGEEKATNPFLRAGEPALARSVDMAPGSDPAAVFAALREWKNRF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.