PharMolix/UniProtQA huggingface dataset:
Protein: GLGA_PASMU
Sequence: MKVLHACSELYPLLKTGGLADVMGALPFAQKEIGIDARIVLPAYPAIKAGIPETTVVSEFDNFAGHIVLRYGEYKGLGVYLIDAPHLYQREGNPYHDQWYNDYADNYKRFALLGWVAAELATGLDSWWHADVVHAHDWHAGLASAYLFNKGRPAKSVFTIHNLAYQGQFAYHHLVEIGLPAGMFHVDGLELHGQISYLKAGLYYSDAVTAVSPTYAKEITTPEFGYGLQGLLTTLNSQGKLVGILNGVDDQIWHPNHDAYIEHHYKLKAMTGKRKNKEALQAYFNLPQDPDALLFVMVTRLTEQKGVDLLIDSAEEIVKQGGQLTILGSGSPHLEAGILHLAQQYPHQIAVKIGYDEALSHLMIAGGDVILVPSRFEPCGLTQLYGLKYGTLPLVRATGGLADTVVNATVENIKSRLATGFVFEQANREALRQALVNAFALWQKQRLWFTVRSVAMEQDFSWQISATGYHALYQRLLSFN
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: SET25_CAEEL
Sequence: MLPAWGTSTEATASHAGWDGDDEGDIRAAYTEDEKKENIPPISLTSVSTNGAYPGQKRRRSESVRTLKPECPPEETQRLRQRRRISATDATQSSRTMNVIEDRKPRVNRARKSQDAPSTSTCGFETPVGTKRKSKAADSQKPPKQSKLRKIDEASTSKAVDNSSKDGKKTTKPAVTQSNRRRSGLSLRPVPIETIFSESSGRESSTEDEADVSHQQRVEKIAKNPIMVVVLPLGPGNYPNNERITVVSTYKSRVNKNCNEARRAQRHGSWSRKGIAFPGIPTKKFTKSDLAKYGAHASNWPAQAAFRSEEGKILIYYEGWTCLTLHRLSVEECARTAPTILEEMSIRDKFIETVKSAAAEEAKLVVEKNQENGIELTLDEALKQIFIEPVPQSSPENVFWIYQDLSYFHTMDNRDLGLAPVFYISSYTQSVRPPCYAYTAINIVDVDAYKRCLESRANMSFADLTGQKIWMPTRSKACENGTKCKCDARFMFLYDPHDVTNLECTPDGKVDFTDFKIDNARIVMECSDACGCSLDCPRRSLQRGQQHPLAVYYEGPEKGFGVRAAANIKAGELVCEYTGDVTLLPTSDPVASSSTKTDDGEEQENPEAPERVDSSYDAAFNAMDTKIIISAKKTGNISRFINHSCDPSSVFVEVYSRRFEEDPLIPRVAVYAIKDIALGEEITIAYYEPGIEWKRSSVKCRCKSTKCMGTLPAF
What is the function of this protein?
Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using mono- and dimethylated H3 'Lys-9' as substrate (PubMed:22939621, PubMed:28428426).  Acts redundantly with the methyltransferase met-2 to position chromosome arms at the nuclear lamina (PubMed:22939621).  Required for small-RNA-induced H3K9 methylation (PubMed:26365259).  Together with met-2, protects and stabilizes repeat-rich genomic regions by suppressing transcription-induced replication stress through methylation of H3K9 (PubMed:27668659).  Suppresses transcription from various repetitive genomic elements through methylation of H3K9; exposure to moderately raised temperature reduces methylation by set-25 leading to de-repression of transcription of repetitive elements lasting at least 3 subsequent generations, despite culture at lower temperatures (PubMed:28428426).  May play a role in transgenerational transmission of environmental information (PubMed:28428426).
What are the official names of this protein?
Histone-lysine N-methyltransferase set-25, Histone H3-K9 methyltransferase set-25.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Nucleus lamina. Note=Colocalizes with its own product and hpl-1 in foci in the peripheral region of the nucleus, in a manner dependent on H3K9me3.
Protein: APOA1_TURTR
Sequence: MKAVLLTLAVLFLTGSQARHFWQQDDPQSSWDRVKDFATVYVDAIKDSGRDYVAQFEASALGKQLNLKLLDNWDSLTSTFAKVREQLGPVTQEFWDNLEKETESLRQEMNKDLEEVKQKVQPYLDEFQKKWQEELQIYRQKVAPLGEELREGARQKVQELQDKLTPLAEEMRDRARSHVETLRQQLAPYSDDLRQRMAARFEMLKAGGGSLAEYHAKASEQLRALGEKAKPALEDLRQGLVPVLESLKVSILAAIDEASKKLNAQ
What is the function of this protein?
Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT).  As part of the SPAP complex, activates spermatozoa motility (By similarity).
What are the official names of this protein?
Apolipoprotein A-I, Apo-AI, ApoA-I, Apolipoprotein A1.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted.
Protein: ERH_TAESO
Sequence: MSHTILLVQQQVKKPESRVWADYETLNQCLEGVCKIYEEQLKQQNPTAPTITYDISQLFKFIDQLADLSCLEFHPATGTYVPHTKDWIKENIYALLRNQAGQ
What is the function of this protein?
May have a role in the cell cycle.
What are the official names of this protein?
Enhancer of rudimentary homolog.
What is the protein family that this protein belongs to?
Belongs to the E(R) family.
Protein: RL17_ALBFT
Sequence: MRHGHGLRKLNRTSEHRLAMLRNMMNSLIEHEVIKTTLPKAKELRRVVEPMITLAKEATVANRRLAFDRLRDRDSVVKLFNDLGPRFKARPGGYTRILKMGFRVGDNAPMALVELVDRAELAEAPTDEKSED
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: SUCC_ENT38
Sequence: MNLHEYQAKQLFARYGLPAPVGYACNTPREAEEAASKIGSGPWVVKCQVHAGGRGKAGGVKVVKSKEEIRAFAEHWLGKRLVTYQTDANGQPVNQILVEAATDIAKELYLGAVVDRSSRRVVFMASTEGGVEIEKVAEETPHLIHKVAIDPLAGPMPYQGRELAFKLGLEGKLVQQFTKIFMGLAKIFLERDLALIEINPLVITTQGDLICLDGKLGADGNALFRQSDLREMRDQSQEDPREAQAAQWELNYVALDGNIGCMVNGAGLAMGTMDIVKLHGGEPANFLDVGGGATKERVTEAFKIILSDDKVKAVLVNIFGGIVRCDLIADGIIGAVEEVGVNVPVVVRLEGNNAELGAKKLADSGLNIIAAKSLTDAAQQVVAAVEGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: Y1594_LACPJ
Sequence: MESWLFLLAILVVAWLGKNQSLQIATVVVLLIKLIPNTSKLLTTIGQKGINWGVTVITVAILIPIATGQIGFRDLWHAFKSPVGWIAVACGVLVSVLSFHGVGLLSATPEITVALVFGTIMGVVLLKGIAAGPIIAAGITYCIIQVLHLSLQ
What are the official names of this protein?
UPF0756 membrane protein JDM1_1594.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CCR4C_ARATH
Sequence: MRCVNRVDCSWSRPSEAYRILPSGGHLSSGFHQCPLSSLSFRSSFVCCSSSTSGPSDSNPESSSNRSYSRRWQNPLPRRQHPDQIPSSQIARDWIDSDTTPVSQALERFTVVSYNILGDGNSSYHRELYSNVSVPYLKWGYRKRLICEELIRLNPDIISMQEVDKYFDLFSMMEKAGYAGSYKRRTGDNVDGCAMFWKADRFGVLERENIEFSQFGMRDNVAQLAVLELRKSNKSRKILLGNIHVLYNPNQGDVKLGQVRSLCSKAHLLSKKWGDIPIVLCGDFNSTPKSPLYNFLASSELNVMEHDKKELSGQKNCRPTKVLETGSKSSNTITFSFCSSWTKEEIRVATGQENSYWAAHPLKLNSSYASVKGSANTRDSVGEPLATSYHSKFLGTVDYLWYSDGLLPARVLDTLPIDVLCKTKGLPCQELGSDHLALVSEFVFEPDG
What is the function of this protein?
Acts as catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover.
What are the official names of this protein?
Carbon catabolite repressor protein 4 homolog 3, CCR4 homolog 3.
What is the protein family that this protein belongs to?
Belongs to the CCR4/nocturin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: CMOB_ACTPJ
Sequence: MIDFRPFYQQIATTNLSAWLETLPLQLKQWEKTTHGDYAKWAKIVDFMPNSTACINLKDKVESIPHTPLSVGETKQLTHHLKQLMPWRKGPYHLHGIHIDTEWRSDFKWDRVLPHLAPLKDRTILDVGCGSGYHMWRMVGEGAKMVVGIDPTELFLCQFEVVRKLLGNDRRANLIPLGIEQMQPLAAFDTVFSMGVLYHRKSPLDHLSQLKAQLVKGGELVLETLVIDGDVNTCLVPADRYAKMKNVYFIPSIDCLINWLEKVGFKNVRCVDQAVTTLEEQRKTDWLENESLVDFLDPNDHSKTIEGYPAPKRAVILANA
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: SC22A_HUMAN
Sequence: MSMILSASVIRVRDGLPLSASTDYEQSTGMQECRKYFKMLSRKLAQLPDRCTLKTGHYNINFISSLGVSYMMLCTENYPNVLAFSFLDELQKEFITTYNMMKTNTAVRPYCFIEFDNFIQRTKQRYNNPRSLSTKINLSDMQTEIKLRPPYQISMCELGSANGVTSAFSVDCKGAGKISSAHQRLEPATLSGIVGFILSLLCGALNLIRGFHAIESLLQSDGDDFNYIIAFFLGTAACLYQCYLLVYYTGWRNVKSFLTFGLICLCNMYLYELRNLWQLFFHVTVGAFVTLQIWLRQAQGKAPDYDV
What is the function of this protein?
May be involved in vesicle transport between the ER and the Golgi complex.
What are the official names of this protein?
Vesicle-trafficking protein SEC22a, SEC22 vesicle-trafficking protein homolog A, SEC22 vesicle-trafficking protein-like 2.
What is the protein family that this protein belongs to?
Belongs to the synaptobrevin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MURE_BACSU
Sequence: MKLTKLLTYLTTEPSVNDSQDPEITSIEMDSREVKKGSLFVCVKGYTVDGHDFAQKAVENGAAAIVAEREVDVNVPVIIVRQSLRALSVLSDAFYGQPTKKLQLIGITGTNGKTSTTHMVDEILKKAGKRTGLIGTMYMKIGDETLPVKNTTPESVTLQKTFKKMNDKHVDTAIMEVSSHALSLGRVHGCDYDIAVFTNLTQDHLDYHKTMDEYRHAKSLLFSQLGGAFNHEHPKRAVLNADDEASAYFEKVTAAHISTYGIKNDADVMAKNISITAQGTSFDLVTNKGTKHITMSLVGQFNVYNVLAAVATCIAAGIPFEIITEAVEELHGVRGRFELVNQQQEFPVIVDYAHTPDSLENVLETCRDMTEGKLFVVVGCGGDRDKTKRPKMAKIAVELADEPIFTSDNPRSEDPRAILRDMEAGVENAYYHSIANREQAIFFAIANAKKGDVVLIAGKGHETYQQIGNETFDFDDAEVAARAIVELNKNKTNS
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPF27_ARATH
Sequence: MATNNGDVLMLEATPEAARPWASAANAEVIDALPYIDDDYGNPLIKSEVDRLVEEEMRRSSKKPADFLKDLPPLPKFDFKNCPVLGKEYERVRAGKPPVRIDFESRYKLEMPPANKRNDDAAWKQYLQKNQRSLQQKLIELENLELMSKLGPELWRQNNHRLEVFLTRMQRLAQEQNEEIEKVNRERKYHQQTTSYELNALSQEWRQLCVKNMEIQSACAMLETQIDSFKKEAAERGWNLEEKLENVEPLQMQ
What is the function of this protein?
Component of the MAC complex that probably regulates defense responses through transcriptional control and thereby is essential for plant innate immunity.  Involved in mRNA splicing.
What are the official names of this protein?
Pre-mRNA-splicing factor SPF27 homolog, Modifier of SNC1 member 4, Protein BCAS2 homolog.
What is the protein family that this protein belongs to?
Belongs to the SPF27 family.
Protein: GCH1_AZOVD
Sequence: MSLEQQYTAILAQLGEDVSREGLVDTPKRAAKAMQYLCRGYQQTLEEVVNGALFSSDNSEMVMVKNIELYSLCEHHMLPFIGKAHVAYLPNGKVLGLSKVARIVDMFARRLQIQENLTRQIAEAVEQVTGASGVGVVIEAQHMCMMMRGVEKQNSTLVTSVMLGHFRSNTATRSEFLSLIK
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: HEM3_PSEPG
Sequence: MSTREIRIATRKSALALWQAEYVKARLEQAHPGLLVTLVPMVSRGDKLLDAPLAKIGGKGLFVKELETALLDNEADIAVHSMKDVPMDFPEGLGLYCICEREDPRDAFVSNTFDSLEALPAGSIVGTSSLRRQAQLLARRPDLQIRFLRGNVNTRLAKLDAGEYDAIILAAAGLIRLGFEDRITSTISVDDSLPAGGQGAVGIECRSADVEIHALLAPLHHADTADRVVAERALNKHLNGGCQVPIACYAVLEGDQLWLRGLVGQPSGGTLLVADARAPRTAAETLGVQVAEDLLSQGAEAILKEVYGEAGHP
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: CYSH_BACCN
Sequence: MLTYETWEEDSMSFSERDETKGALAVLEWAYKQYNDEIVYACSFGVEGMVLLHLINEVNPFAQVVFLDTNVHFCETYALIERVRQRFPKLNIIEKQPGLTLEEQEDKYGKDLWEHNPNLCCKLRKILPLEELLANKNAWISGLRREQSETRKHTKFINQDHRFQSIKICPLIHWTWKEVWRYVYKHNLPYNPLHDVGYPSIGCEKCTLPVGKYGSSRDGRWAGSVKTECGLHDQ
What is the function of this protein?
Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
What are the official names of this protein?
Adenosine 5'-phosphosulfate reductase, APS reductase, 5'-adenylylsulfate reductase, Thioredoxin-dependent 5'-adenylylsulfate reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAS29_CAEEL
Sequence: MISKNTSFCGFLILVLATCMSAQFVSNESIKLHDILKPSATHRLFDTLQYSVEEQYSDSHLSFDVSTIYNYSEKPISIGKLNKKYRDILFEGDMAISYKQLSMIVNGSTEYRKAIKSRRRGNKINGESTDRTKRQAYLDNNYPATIWKNGVAFMFHESLTPIAKTAILKAVHFWYRETCIEFHPRTFQKEYLLFIGNDDGCWSTVGRDASQGKQVVSIGNGCEHFGVTSHELAHALGIFHEQSRFDRDESVVFNPRVVERDLLFNFAKISPRQMSTYGLPYDIGSVMHYTPTEFSNIPSIPTLAAIDTNLQQTMGQLEGPSFVDVHIMNQHYQCQEKCPTQAPCQNGGFTNSRNCKVCKCPTGFGGAYCQLIASSFSPFCGGYLNAEETTRRFDITIRQSTTTRSKTCVYHIKAPEGKRIIIDILKIDSKCIEGCWQDGLELKMKKDFRPVGYRFCCPESSRRKVISEGNMVPFMVFSKEHDFSVSFEYSFVSTSAGFDDEKNDSDVIVDNLDGVFVSDTSLLQRIGFRRQL
What is the function of this protein?
Metalloprotease.
What are the official names of this protein?
Zinc metalloproteinase nas-29, Nematode astacin 29.
What are the subcellular locations of this protein?
Secreted.
Protein: CH60_SALEP
Sequence: MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQSIITEGLKAVAAGMNPMDLKRGIDKAVAAAVEELKALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDRGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKIADLKGQNEDQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPKSDAPDLGAAGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUCL_BACSU
Sequence: MFTMDDLNQMDTQTLTDTLGSIFEHSSWIAERSAALRPFSSLSDLHRKMTGIVKAADRETQLDLIKKHPRLGTKKTMSDDSVREQQNAGLGKLEQQEYEEFLMLNEHYYDRFGFPFILAVKGKTKQDIHQALLARLESERETEFQQALIEIYRIARFRLADIITEKGETQMKRTMSYGKGNVFAYRTYLKPLTGVKQIPESSFAGRDNTVVGVDVTCEIGGEAFLPSFTDGDNTLVVATDSMKNFIQRHLASYEGTTTEGFLHYVAHRFLDTYSHMDTITLTGEDIPFEAMPAYEEKELSTSRLVFRRSRNERSRSVLKAERSGNTITITEQYSEIMDLQLVKVSGNSFVGFIRDEYTTLPEDGNRPLFVYLNISWQYENTNDSYASDPARYVAAEQVRDLASTVFHELETPSIQNLIYHIGCRILARFPQLTDVSFQSQNHTWDTVVEEIPGSKGKVYTEPRPPYGFQHFTVTREDAEKEKQKAAEKCRSLKA
What is the function of this protein?
Catalyzes two steps in the degradation of uric acid, i. e.  the oxidation of uric acid to 5-hydroxyisourate (HIU) and the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin.
What are the official names of this protein?
Uric acid degradation bifunctional protein PucL.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the uricase family.
Protein: PYRE_RALSO
Sequence: MSQNSELRQSFIRFAVEAGVLSFGEFVTKAGRTSPYFFNAGKFSDGALLGQVAQFYAKTLLDSGVQFDMLFGPAYKGITLASATAVALAGMGRNVGFAYNRKEAKDHGEGGSLVGAKLQGRVVIVDDVISAGTSVRESVELIRNAGATPAAVLILMDRMERSGNAVDIGERSAVQDVQAQYGMPVVSIANLDDLLGYLDHAGDPALAGYRAKAAAYRDKYGVSAVV
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: CP2H2_CHICK
Sequence: MDFLGLPTILLLVCISCFLIAAWRSTSQRGKEPPGPTPIPIIGNVFQLNPWDLMESFKELSKKYGPIFTIHLGPKKVVVLYGYDVVKEALIDNGEAFSGRGNLPLFEKVFKGTGIVTSNGESWRQMRRFALTTLRDFGMGKKSIEERIQEEARFLVERIRNTHEKPFNPTVFLMHAVSNIICSTVFGDRFDYEDKKFLDLIEMLDENERYQNRIQTQLYNFFPTILDYLPGPHKTLIKSIETVDDFITEIIRAHQESFDASCPRDFIDAFINKMQQEKENSYFTVESLTRTTLDLFLAGTGTTSTTLRYGLLILLKHPEIEEKMHKEIDRVVGRDRSPCMADRSQLPYTDAVIHEIQRFIDFLPVNLPRAVIKDTKLRDYFIPKDTMIFPLLSPILQDCKEFPNPEKFDPGHFLNANGTFRKSNYFMPFSAGKRICAGEGLARMELFLFLTSILQNFSLKPVKDRKDIDISPIVTSAANIPRPYEVSFIPR
What is the function of this protein?
Cytochromes P450 are a group of heme-thiolate monooxygenases.  In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway.  It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
What are the official names of this protein?
Cytochrome P450 2H2, CYPIIH2, Cytochrome P450 PCHP7.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: MINE_ECO24
Sequence: MALLDFFLSRKKNTANIAKERLQIIVAERRRSDAEPHYLPQLRKDILEVICKYVQIDPEMVTVQLEQKDGDISILELNVTLPEAEELK
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: Y5182_ARATH
Sequence: MERHFVFIATYLLIFHLVQAQNQTGFISVDCGLSLLESPYDAPQTGLTYTSDADLVASGKTGRLAKEFEPLVDKPTLTLRYFPEGVRNCYNLNVTSDTNYLIKATFVYGNYDGLNVGPNFNLYLGPNLWTTVSSNDTIEEIILVTRSNSLQVCLVKTGISIPFINMLELRPMKKNMYVTQSGSLKYLFRGYISNSSTRIRFPDDVYDRKWYPLFDDSWTQVTTNLKVNTSITYELPQSVMAKAATPIKANDTLNITWTVEPPTTQFYSYVHIAEIQALRANETREFNVTLNGEYTFGPFSPIPLKTASIVDLSPGQCDGGRCILQVVKTLKSTLPPLLNAIEAFTVIDFPQMETNENDVAGIKNVQGTYGLSRISWQGDPCVPKQLLWDGLNCKNSDISTPPIITSLDLSSSGLTGIITQAIKNLTHLQILDLSDNNLTGEVPEFLADIKSLLVINLSGNNLSGSVPPSLLQKKGMKLNVEGNPHILCTTGSCVKKKEDGHKKKSVIVPVVASIASIAVLIGALVLFLILRKKRSPKVEGPPPSYMQASDGRLPRSSEPAIVTKNRRFSYSQVVIMTNNFQRILGKGGFGMVYHGFVNGTEQVAVKILSHSSSQGYKQFKAEVELLLRVHHKNLVGLVGYCDEGDNLALIYEYMANGDLKEHMSGTRNRFILNWGTRLKIVIESAQGLEYLHNGCKPPMVHRDVKTTNILLNEHFEAKLADFGLSRSFLIEGETHVSTVVAGTPGYLDPEYHRTNWLTEKSDVYSFGILLLEIITNRHVIDQSREKPHIGEWVGVMLTKGDIQSIMDPSLNEDYDSGSVWKAVELAMSCLNHSSARRPTMSQVVIELNECLASENARGGASRDMESKSSIEVSLTFGTEVSPNAR
What are the official names of this protein?
Probable LRR receptor-like serine/threonine-protein kinase At1g51820.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: MSHD_CORGB
Sequence: MNTSDRIKSTQIALDRDLREQALLLLKEVRAVDGVDAFSEQFVRGLAEPGLGHSHLIVTLNDKLVGLAATDEETTELAVHPAHRRQGIGKALIDAAPTSSIWAHGNTAGAQALASTLRMKKTRELLVMEISDRALDGSAAYKDPDGITHSSLANAPVEKSVAEAKWLQSNNEAFDWHPEQGGWTTHRLAQAQKADWYKDSDVLFLWDGEEIVGFHWVKQHSPELQEIYVVGLSSAYRGRGLGDPLVRLGLHHMRAHGARKVILYVEADNTPAVAAYEKLGFTVAESHVVYEK
What is the function of this protein?
Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
What are the official names of this protein?
Mycothiol acetyltransferase, MSH acetyltransferase, Mycothiol synthase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. MshD subfamily.
Protein: HEM3_THIDA
Sequence: MHTLTIASRESALAMWQAEHIRDRLRELHPECKVNILGMTTRGDQILDVTLSKIGGKGLFVKELEVALAAGEADLAVHSMKDVPMELPPGFELAVIGEREDPRDAFVSNRYARLSDLPPGSVVGTSSLRREAQLRARYPHLTVKPLRGNVGTRLKKLDEGQFDAILLAAAGLKRLGLGARIKSLLSVEESIPAAGQGALGIEIRSGNTAVAAMLAPLNDPVTAACVRAERQVSRVLGGSCQVPLGAHASYKDGRLLLEGFVAKPDGSRFLVDRAEGDASDPEAVGQALADKLLAQGARAVLDALPA
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: ATPL_SYNFM
Sequence: MQFFVYSAVAAGFGIAIAAFGCGIGQGMAVRGAVEGIARNPEASGKVTVTMLIGLAMIESLSIYALVVSLILIYANPVSTAMQGFVGLGK
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VL2_HPV57
Sequence: MSPRAKRRKRASPTDLYRTCKQAGTCPPDIIPRVEQDTLADRILKWGSLGVFFGGLGIGTGSGTGGRTGYIPVGTRPTTVVDVGLAPRPPVVIEPVGASEPSIVNLVEDSSIINAGSSHPTFTGTGGFEVTTSTVTDPAVLDITPSGNGVQVSSSSFVNPLFTDPAIIEAPQAGEVTGHVLVSTATSGSHGFEEIPMQTFATSGGDGGEPISSTPVPGVRRVAGPRLYSRANQQVRVRDPAFIDRPADLVTFDNPVYDPEETIIFQHPGLHEPPDPDFLDIVSLHRPALTSTRQGTVRFSRLGRRATLRTRSGKQIGARVHFYHDISPVAPEELEMEPLLPPTSEPLYDIYAESDFLQPLDSDVPAAPRGTLSLADTAVSASTASTLRGATTVPLSGGVDVPVYTGPDIDPSVGPGMGPLVPVIPAIPSSVYIVGGDYYLLPSYVLWPKRRKRVHYFFADGYVAA
What is the function of this protein?
Minor protein of the capsid that localizes along the inner surface of the virion, within the central cavities beneath the L1 pentamers.  Plays a role in capsid stabilization through interaction with the major capsid protein L1.  Once the virion enters the host cell, L2 escorts the genomic DNA into the nucleus by promoting escape from the endosomal compartments and traffic through the host Golgi network.  Mechanistically, the C-terminus of L2 possesses a cell-penetrating peptide that protudes from the host endosome, interacts with host cytoplasmic retromer cargo and thereby mediates the capsid delivery to the host trans-Golgi network.  Plays a role through its interaction with host dynein in the intracellular microtubule-dependent transport of viral capsid toward the nucleus.  Mediates the viral genome import into the nucleus through binding to host importins.  Once within the nucleus, L2 localizes viral genomes to host PML bodies in order to activate early gene expression for establishment of infection.  Later on, promotes late gene expression by interacting with the viral E2 protein and by inhibiting its transcriptional activation functions.  During virion assembly, encapsidates the genome by direct interaction with the viral DNA.
What are the official names of this protein?
Minor capsid protein L2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L2 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host early endosome. Host Golgi apparatus.