PharMolix/UniProtQA huggingface dataset:
Protein: KDM4D_HUMAN
Sequence: METMKSKANCAQNPNCNIMIFHPTKEEFNDFDKYIAYMESQGAHRAGLAKIIPPKEWKARETYDNISEILIATPLQQVASGRAGVFTQYHKKKKAMTVGEYRHLANSKKYQTPPHQNFEDLERKYWKNRIYNSPIYGADISGSLFDENTKQWNLGHLGTIQDLLEKECGVVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHLGEPKTWYVVPPEHGQRLERLARELFPGSSRGCGAFLRHKVALISPTVLKENGIPFNRITQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKMASQCSCGEARVTFSMDAFVRILQPERYDLWKRGQDRAVVDHMEPRVPASQELSTQKEVQLPRRAALGLRQLPSHWARHSPWPMAARSGTRCHTLVCSSLPRRSAVSGTATQPRAAAVHSSKKPSSTPSSTPGPSAQIIHPSNGRRGRGRPPQKLRAQELTLQTPAKRPLLAGTTCTASGPEPEPLPEDGALMDKPVPLSPGLQHPVKASGCSWAPVP
What is the function of this protein?
Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code.  Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'.  Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues.  Demethylation of Lys residue generates formaldehyde and succinate.
What are the official names of this protein?
Lysine-specific demethylase 4D, JmjC domain-containing histone demethylation protein 3D, Jumonji domain-containing protein 2D, [histone H3]-trimethyl-L-lysine(9) demethylase 4D.
What is the protein family that this protein belongs to?
Belongs to the JHDM3 histone demethylase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLUQ_XANCP
Sequence: MSSLPYRGRFAPSPTGPLHFGSLLAALGSWLLARHAGGEWHVRIEDIDPPRAEPGASERQLHTLAAFGLHSDGPVLYQSDRDAYYEAALSRLLRSGAAFECSCSRAELAAMGGIHHVCVAPLGIRRAVRLRVPPNTQASFQDALQGRITQDVYSEVGDVVLRRADGYWAYQLAVVVDDAAQGITDVVRGADLLDSTPRQLVLQQALGVAPPRYLHLPLILGADGRKLSKSHAAQPVDDSDPLPALRAAWRALGQAPAALPARASVAGVLQHAVQHFSPQRLPRVASLDAATRIDAPA
What is the function of this protein?
Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp).  Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.
What are the official names of this protein?
Glutamyl-Q tRNA(Asp) synthetase, Glu-Q-RSs.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
Protein: Y1240_BACC0
Sequence: MAKDSSFDIVSKVELPEVTNAINTALKEIQNRYDFKGSKSDIKLEKEVLVLTSDDEFKLEQVKDVLISKLVKRNVPIKNLDYGKVEAAAGNTVRQRATLQQGIDKDNAKKINNIIKEMKLKVKTQVQDDQVRVTAKSRDDLQAVIAAVRSADLPIDVQFINYR
What are the official names of this protein?
UPF0234 protein BCAH820_1240.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: RUVB_NITSB
Sequence: MERIVEVEKFSEESSFETTLRPSDWDEYIGQEKIKNNLKVFIQACKKRGETLDHVLFFGPPGLGKTTLSLIIASQMEANIKITAAPMIEKSGDLAAILTNLEEGDILFIDEIHRLSPAIEEILYPAMEDFRLDIIIGSGPAAQTIKIDLPKFTLIGATTRAGMLSSPLRDRFGMHFRLQFYTPQELAQIITNAANKLSKDIDAEAALEIAKRSRGTPRIALRLLKRVRDFSDVADEKTITLKRTQKALEALGVDERGFDELDLKLLKLLADAKGKPLGLSTIAAALSEDEGTIEDVIEPFLLANGYLERTARGRMATLKTYEILKLTPNIQNSLF
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: GTAY_DICDI
Sequence: MNFDNKNKNDNYQESIQRIVNQRNNLLKEIENKINQQFGNGNYETLIKSIELIYEIEEKIKRIKELNSLQCDLLEYINPTNSMVPTSPFSSPNFPNSNIEIIDQKQHHQQKLQQQQQQQQQQQQQQQQQQQQQQQQQQQQKQQQKQQQQQLQQSHTKQSPKKQGHNSKQQFLTSLEKHKDQKEENEENEENEENEENEENEENKEKDVEVAKSNKPKRGRPSKPKPEYCFRYGTRSCPYWRKNVIKGELVDVCNACGLHLMKKEKKDLMEKQKNSIKNLLNNDEIITNYDDLGFVLYN
What are the official names of this protein?
Putative GATA zinc finger domain-containing protein 25.
Protein: PUR5_VIGUN
Sequence: MSLSACAELSRCFAAAASAKPNSGKSNSTAATSLVISSPIGHDGAVSSVSRSRKTSRIVAEASQGLTYRDAGVDIDAGAELVRRIAKMAPGIGGFGGLYPLGDSYLVAGTDGVGTKLMLAFETGIHDTIGIDLVAMSVNDIVTSGAKPLFFLDYFATGRLDVDVAEKVVKGIVDGCKQSDCVLLGGETAEMPGLYKEGEYDLSGCAVGIVKKDSVINGKNIVAGDVIIGLPSSGVHSNGFSLVRRVLAQSGLSLKDQLPGSNITLAEALMAPTVIYVKQVLDLISKGGVKGIAHITGGGFTDNIPRVFPEGLGALIYDGSWEVPAVFRWLQEAGKIEDSEMRRTFNMGIGMILVVSPEAANRILENKGQADKFYRIGEIISGNGVTFS
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, chloroplastic/mitochondrial, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase, VUpur5.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast. Mitochondrion.
Protein: GLUQ_NEIMA
Sequence: MYTGRFAPSPTGLLHIGSLLTAAASYADARSNGGKWLVRMEDLDPPREMPGAANHILHTLEAFGFEWDGEVAYQSRRYALYEETLCRLQTAGLVYPCHCSRKDWQTGARRGADGFVYNGRCRNPQQRPAPQGKQPAWRIRVPDRVIGFSDGIVGGYAQNLAGDIGDFVLLRADGYWAYQLAVVADDAEQGVTHIVRGQDLLVSTPRQIYLQQCLDVPTPQYAHLPLLTNAQGQKWSKQTLAPALDLNRREQLLRQVFRYLNLPEAPEADRPAELLDWAVAHWDMDKVPKHAITTP
What is the function of this protein?
Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp).  Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.
What are the official names of this protein?
Glutamyl-Q tRNA(Asp) synthetase, Glu-Q-RSs.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
Protein: DDL_SHEHH
Sequence: MTQKNLLLLCGGGGDEHSISLLSANFFETQLATLPHFNVLRVELNAKGQYRTQAGELCELTNSKQIRFNDQSKAPWDVDYVIPCIHGYPGETGDIQSYFELINLPYFGCDSEASSNCFNKVTAKMWFSALGIRNTPYIFLNEFNQQAIEETERALEKWGSIFIKAASQGSSVGCYRVDNKEQLANSLEEAFKYSPYVVVEKTINARELEVAAYEVDGEIIATKPGEIICASNTFYSFDEKYAENSQAQTVIEADVDEVIAKQIQEYAIKAFKGMKLRHLSRIDFFLTDENEILLNEINTFPGQTQISMFPKMLQNHGHNFAQYLSGNIMAQLK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCC2D_BOVIN
Sequence: MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSAKSLLKKPDGVKKRKSSSSVQMMESTESSNTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIN
What is the function of this protein?
Calcium/calmodulin-dependent protein kinase involved in the regulation of Ca(2+) homeostatis and excitation-contraction coupling (ECC) in heart by targeting ion channels, transporters and accessory proteins involved in Ca(2+) influx into the myocyte, Ca(2+) release from the sarcoplasmic reticulum (SR), SR Ca(2+) uptake and Na(+) and K(+) channel transport.  Targets also transcription factors and signaling molecules to regulate heart function.  In its activated form, is involved in the pathogenesis of dilated cardiomyopathy and heart failure.  Contributes to cardiac decompensation and heart failure by regulating SR Ca(2+) release via direct phosphorylation of RYR2 Ca(2+) channel on 'Ser-2808'.  In the nucleus, phosphorylates the MEF2 repressor HDAC4, promoting its nuclear export and binding to 14-3-3 protein, and expression of MEF2 and genes involved in the hypertrophic program.  Is essential for left ventricular remodeling responses to myocardial infarction.  In pathological myocardial remodeling acts downstream of the beta adrenergic receptor signaling cascade to regulate key proteins involved in ECC.  Regulates Ca(2+) influx to myocytes by binding and phosphorylating the L-type Ca(2+) channel subunit beta-2 CACNB2.  In addition to Ca(2+) channels, can target and regulate the cardiac sarcolemmal Na(+) channel Nav1. 5/SCN5A and the K+ channel Kv4. 3/KCND3, which contribute to arrhythmogenesis in heart failure.  Phosphorylates phospholamban (PLN/PLB), an endogenous inhibitor of SERCA2A/ATP2A2, contributing to the enhancement of SR Ca(2+) uptake that may be important in frequency-dependent acceleration of relaxation (FDAR) and maintenance of contractile function during acidosis.  May participate in the modulation of skeletal muscle function in response to exercise, by regulating SR Ca(2+) transport through phosphorylation of PLN/PLB and triadin, a ryanodine receptor-coupling factor.  In response to interferon-gamma (IFN-gamma) stimulation, catalyzes phosphorylation of STAT1, stimulating the JAK-STAT signaling pathway (By similarity).
What are the official names of this protein?
Calcium/calmodulin-dependent protein kinase type II subunit delta, CaM kinase II subunit delta, CaMK-II subunit delta.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
What are the subcellular locations of this protein?
Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Sarcoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TSP_MOUSE
Sequence: MTPTIFLVILCLGVASAVIVPEAQLDAELQEQKDKEVLIKAVWSKFMKTNKLHSSENDQETEGSNIEMSASGQLTDEELMKIMTTVLHPMFEEEENKPQPVVDDPEFEDYTESGDGFFVPNQPQ
What is the function of this protein?
It may be a growth factor/hormone, perhaps involved in interaction between the maternal and fetal systems in maintenance of pregnancy.
What are the official names of this protein?
Trophoblast-specific protein alpha.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: CH10_LAWIN
Sequence: MNLKPLNDRVLVKRLESEEKTAGGLYIPDTAKEKPSRGEVVAVGPGKHTDDGKLIPMAVKAGDTVLFNKYAGTEVKLDGVEHLVMREDDILAVITGETGRK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_BURM1
Sequence: MGRRYFGTDGIRGTVGDAPITPDFVLRLGYAAGKVLAGTADVAPGARPTVLIGKDTRVSGYMLEAALEAGFSAAGVDVMLAGPMPTPGVAYLTRALRLSAGVVISASHNPYPDNGIKFFSADGNKLPDDTEAAIEAWLDKPLECAPSDGLGKARRLDDAAGRYIEFCKSTFPAAFDLRGLKLVVDCAHGAAYQVAPHVFHELGADVIPIGVAPNGFNINDGVGATAPDALMRAVRANRADLGIALDGDADRLQIVDASGRLYNGDELLYVLVQDRIATDGKVEGAVGTLMTNLAVEVALQRAGVQFVRAAVGDRYVLEKLREHGWQLGAEGSGHILSLDRHSTGDGIVSALLVLAALKRSGKTLAQMLDGVTLFPQKLINVRMKPGADWKDSASIRAAIETAEAALAGSGRVLIRASGTEPVLRVMVEAQQAADATRHAEAIAEAVRAATA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: F264_HUMAN
Sequence: MASPRELTQNPLKKIWMPYSNGRPALHACQRGVCMTNCPTLIVMVGLPARGKTYISKKLTRYLNWIGVPTREFNVGQYRRDVVKTYKSFEFFLPDNEEGLKIRKQCALAALRDVRRFLSEEGGHVAVFDATNTTRERRATIFNFGEQNGYKTFFVESICVDPEVIAANIVQVKLGSPDYVNRDSDEATEDFMRRIECYENSYESLDEDLDRDLSYIKIMDVGQSYVVNRVADHIQSRIVYYLMNIHVTPRSIYLCRHGESELNLKGRIGGDPGLSPRGREFAKSLAQFISDQNIKDLKVWTSQMKRTIQTAEALGVPYEQWKVLNEIDAGVCEEMTYEEIQDNYPLEFALRDQDKYRYRYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEQLPYLKCPLHTVLKLTPVAYGCKVESIFLNVAAVNTHRDRPQNVDISRPPEEALVTVPAHQ
What is the function of this protein?
Synthesis and degradation of fructose 2,6-bisphosphate.
What are the official names of this protein?
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4, 6PF-2-K/Fru-2,6-P2ase 4, PFK/FBPase 4, 6PF-2-K/Fru-2,6-P2ase testis-type isozyme.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the phosphoglycerate mutase family.
Protein: UNG_BACC0
Sequence: MKHVLKNDWGPLLAPEFEKEYYRELDVFLKEEYSIHVVYPKVEEIFNALEYTSYENTKVVILGQDPYHGPNQAHGLSFSVQPGVKTPPSLLNMYKELRDEYGYDIPNNGYLVKWAEQGVLLLNTVLTVRQGEANSHKGKGWEHFTDRVIELLNEREKPVIFILWGRHAQAKKKLITNSNHHIIESVHPSPLSARRGFFGSKPYSKVNTILANMGEREIDWEIPNL
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YH18_YEAST
Sequence: MDRKRSFEKIVVSVMVGKNVQKFLTFVEDEPDFQGGPIPSKYLIPKKINLMVYTLFQVHTLKFNRKDYDTLSLFYLNRGYYNELSFRVLERCYEIASARPNDSSTMRTFTDFVSGTPIVRSLQKSTIRKYGYNLAPYMFLLLHVDELSIFSAYQASLPGEKKVDTERLKRDLCPRKPTEIKYFSQICNDMMNKKDRLGDVLATAQRIRRRYNKNGSSEPRLKTLDGLTSERWIQWLGLESDYHCSFSSTRNAEDVVAGEAASSDHDQKISRVTRKRPREPKSTNDILVAGRKLFGSSFEFRDLHQLRLCHEIYMADTPSVAVQAPPGYGKTELFHLPLIALASKGDVKYVSFLFVPYTVLLANCMIRLGRRGCLNVAPVRNFIEEGCDGVTDLYVGIYDDLASTNFTDRIAAWENIVECTFRTNNVKLGYLIVDEFHNFETEVYRQSQFGGITNLDFDAFEKAIFLSGTAPEAVADAALQRIGLTGLAKKSMDINELKRSEDLSRGLSSYPTRMFNLIKEKSEVPLGHVHKIWKKVESQPEEALKLLLALFEIEPESKAIVVASTTNEVEELACSWRKYFRVVWIHGKLGCCRKGVSHKGVCH
What are the official names of this protein?
Uncharacterized protein YHR218W.
Protein: TRM1_SULIM
Sequence: MKLKEVTEGKVRIFVPDPKEYMIEGKFDPSWAPVFYNPKMTFNRDLSVIVVSLLKPKIILDALSATGIRGIRYYVESWKSEQLILNDKNSTAASLIQINVKNNGIENAKIYNKDANALLYEIKSEYIDIDPFGSPVPFILSSINATIRNGIVAFTATDLSPLEGSSRTSCRRKYDAINYKLSSSKELGLRILIGKIIREAATLEKTVHPLFSFYADYYYRLFVIVESGARKADENINKNLKYFGECPRCGFQTFVDENCKTKCPICGENFIIIGPLYIGPLHNMEFLKRMIDTYSDFNYLSSFNRIQKLLNVIEKEAKYKSVFYNISKLASKLKVSAIPPIDSILECLGDASKTHFAPTGIRTDKGYEEIIRCVKSLR
What is the function of this protein?
Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.
What are the official names of this protein?
tRNA (guanine(26)-N(2))-dimethyltransferase, tRNA 2,2-dimethylguanosine-26 methyltransferase, tRNA(guanine-26,N(2)-N(2)) methyltransferase, tRNA(m(2,2)G26)dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
Protein: COX2_TAMRF
Sequence: MAYPFELGFQDATSPIMEELLHFHDHTLMIVFLISSLVLYIISLMLTTKLTHTSTMDAQEVETIWTILPAIILILIALPSLRILYMMDEINDPSLTVKTMGHQWYWSYEYTDYEDLNFDSYMIPTSDLNPGELRLLEVDNRVVLPMELPIRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQATLTSTRPGLYYGQCSEICGSNHSFMPIVLELVPLKHFENWSSSML
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MCCA_ARATH
Sequence: MSMMTVWALRRNVRRKNHSMLVRYISGSASMKPKEQCIEKILVANRGEIACRIMRTAKRLGIQTVAVYSDADRDSLHVKSADEAVRIGPPSARLSYLSGVTIMEAAARTGAQAIHPGYGFLSESSDFAQLCEDSGLTFIGPPASAIRDMGDKSASKRIMGAAGVPLVPGYHGHEQDIDHMKSEAEKIGYPIIIKPTHGGGGKGMRIVQSGKDFADSFLGAQREAAASFGVNTILLEKYITRPRHIEVQIFGDKHGNVLHLYERDCSVQRRHQKIIEEAPAPNISEKFRANLGQAAVSAARAVGYYNAGTVEFIVDTESDQFYFMEMNTRLQVEHPVTEMIVGQDLVEWQIRVANGEPLPLSQSEVPMSGHAFEARIYAENVPKGFLPATGVLNHYRPVAVSPSVRVETGVEQGDTVSMHYDPMIAKLVVWGGNRGEALVKLKDCLSNFQVAGVPTNINFLQKLASHKEFAVGNVETHFIEHHKSDLFADESNPAATEVAYKAVKHSAALVAACISTIEHSTWNESNHGKVPSIWYSNPPFRVHHEAKQTIELEWNNECEGTGSNLISLGVRYQPDGSYLIEEGNDSPSLELRVTRAGKCDFRVEAAGLSMNVSLAAYLKDGYKHIHIWHGSEHHQFKQKVGIEFSEDEEGVQHRTSSETSSHPPGTIVAPMAGLVVKVLVENEAKVDQGQPILVLEAMKMEHVVKAPSSGSIQDLKVKAGQQVSDGSALFRIKG
What is the function of this protein?
Biotin-attachment subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3-methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism.
What are the official names of this protein?
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial, MCCase subunit alpha, 3-methylcrotonyl-CoA carboxylase 1, 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: ACUK_TRIVH
Sequence: MSPHQTTGQESDNMTVNGENAQASSQYIQSNEEMTDTIATEKKASAAKAAKDPSRPKRKKAKRACYACQRGHLTCGDERPCQRCIKRGFQDACHDGVRKKAKYLHDAPNEALMAGVGATLYNQRNTAQNNVNASNTSPGAPQQITSPNFYNTQQSPDYNGFPQNKTELQDSTVGPDNYASQSPVSPTYQISQGLSTQGLSPSLPQSTSETPSAANPAPGQFNSTFFDPSDPALFNFDLASMNFGNHYGALEFGMLGHMATGVGDTPPSDSGAQRGSIGQNGSGTFGLTGSSFSESPSNQAPYLFSESGMNDWTQTAPVNRRSMYGSNANLVAGNMSDKPHAFAIESAPANFASPASNESPMMTTSSATFEDTTNSGAFNSRQNVPVSQQRQQPVVSTPQLKQQNLNLGSRRRHKNASSIYDSVKDPYSYTSGFHSLTAFIQRRFSPQKTLRIAKALASIRPSFIATTKTLNRDDLIFMEKCFQRTLWEYEDFINACGTPTIVCRRTGEIAAVGKEFSILTGWKKEVLLGKEPNHNVNTGGSSGLMTGSTSRGSYTPRPYSSEVYNSSATATPRTQPVFLAELLDDDSVIEFYEDFAKLAFGDSRGSVMTTCKLLKYKTKAESDILAGSNGEADAGLNGEATSNETNELNGSHTNGATTNGRGQRRWGKGEIAGEAGMNQLGFRDGKVECSYCWTVKRDVFDIPMLIVMNVSCLFLEPLRSRAMTDIN
What is the function of this protein?
Transcription factor which regulates nonfermentable carbon utilization.  Activator of gluconeogenetic genes (By similarity).
What are the official names of this protein?
Transcription activator of gluconeogenesis TRV_01442.
What is the protein family that this protein belongs to?
Belongs to the ERT1/acuK family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GUAC_STRP2
Sequence: MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVVPANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEYDFVSQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELENAGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRILLPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
Protein: PTC71_DROER
Sequence: MITRLKNWPRLLKTPLQIARHSIQQFSHLAGHYERPPQSGKSSRDPYLVTVVQGRSKKPRFPGERANQRFGEDSWFVRSTPLAEVMGVADGVGGWRDVGVDAGRFAKELMTCCSGQTQRSGFDGRSPRNLLIASFQELTHREHPVVGSSTACLATMHRKDCTLYTANLGDSGFLVVRNGRVLHRSVEQTHDFNTPYQLTVPPEDRKECYYCDKPEMAVSTRHSLLPGDLVLLATDGLFDNMPESMLLKILNGLKERGERDLLQCASQVVEKARELSLNATFQSPFAIKARQHNVSYSGGGKPDDITLILASVEVQSA
What are the official names of this protein?
Protein phosphatase PTC7 homolog fig, Fos intronic gene protein.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: QUEF_HAHCH
Sequence: MELEKHTHLGKATEYPEEYSPSWLTPIPRAKSRETLGLSGKPDFVGEDLWNGYELSWLNSKGKPEVALGVFRIRCDSLNIIESKSFKLYLNSFNQSRFTSREEVEALMRKDLSAAAQGEVSVTLLSVTDWRDEPSFWRDAENLDVLDIDVDVYTPDASLLPDPVGDDVVEETLSSDLLKSNCPVTGQPDWATLYIHYRGKPLEKAALLKYIVSMRSHQDFHEHCVESVYLTLMQRYQPEKLAVYARYTRRGGLDINPLRSNYPLAADNFKLPRQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YHI1_MYCLE
Sequence: MATIFTKIINRELPGRFVYEDDDVVAFLTIEPMTQGHTLVVPCAEIDQWQNVDPAIFGRVIAVSQLIGKGVCRAFNAERAGVIIAGFEVPHLHIHVFPTHSLSNFSFANVDRNPSPESLDAAQDKIKAALTQLA
What are the official names of this protein?
Uncharacterized HIT-like protein ML2237.