PharMolix/UniProtQA huggingface dataset:
Protein: COF_SALPK
Sequence: MARLAAFDMDGTLLMPDHHLGRETIATLARLRERDITLTFATGRHVLEMRHILGTLSLDAYLITGNGTRIHSLEGDVLHRQDLDPQVADTVMHHAWDTRASMHVFNDNGWFTGQEIPALLQAHVYSGFRYQVIDIKSIPAHQVTKICFCGDHDDLIRLRIQLNEALEERAHLCFSAVDCLEVLPLGCNKGSALAVLSNHLGLSLADCMAFGDAMNDREMLGSVGRGLIMGNAMPQLIAALPHLSVIGHCGNQAVSHFLTHWLDNPHLPYSPE
What is the function of this protein?
Catalyzes the hydrolysis of 4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5-hydroxymethylpyrimidine phosphate (HMP-P).
What are the official names of this protein?
HMP-PP phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. Cof family.
Protein: V_MEASY
Sequence: MAEEQARHVKNGLECIRALKAEPIGSLAIGEAMAAWSEISDNPGQERATYKEEKAGGSGLSKPCLSAIGSTEGGAPRIRGQGSGESDDDTETLGIPSRNLQASSTGLQCHYVYDHSGEAVKGIQDADSIMVQSGLDGDSTLSEGDNESENSDVDIGEPDTEGYAITDRGSAPISMGFRASDVETAEGGEIHELLRLQSRGNNFPKLGKTLNVPPPPDPGRASTSETPIKKGHRREISLIWDGDRVFIDRWCNPMCSKVTLGTIRARCTCGECPRVCEQCRTDTGVDTRIWYHNLPEIPE
What is the function of this protein?
Plays an essential role in the inhibition of host immune response.  Prevents the establishment of cellular antiviral state by blocking interferon-alpha/beta (IFN-alpha/beta) production and signaling pathway.  Interacts with host IFIH1/MDA5 and DHX58/LGP2 to inhibit the transduction pathway involved in the activation of IFN-beta promoter, thus protecting the virus against cell antiviral state.  Blocks the type I interferon signaling pathway by interacting with host TYK2 and thereby inhibiting downstream STAT1 and STAT2 phosphorylation.  Moderately affects the type II interferon signaling (By similarity).
What are the official names of this protein?
Non-structural protein V.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses V protein family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: RS13_GILMI
Sequence: MGRMHAPGKGLSQSALPYRRSVPTWLKLTSDDVKEQIFKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKSKGLAPDLPEDLYHLIKKAVAVRKHLERNRKDKDAKFRLILIESRIHRLARYYKTKRVLAPNWKYXSSTASALVA
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
40S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: GLMU_XYLFT
Sequence: MPLSLPLHIVILAAGEGKRMKSALPKVLHPIAGKPMLAHVITTARALTPDAIHVVYGHAGNQVRAAFADQTDLHWVEQTQQLGTGHAVKQTMSAIPNAANVLVLYGDVPLIRAETLQRLPRASTPIAVLVTELANPAGYGHIVRNSEGKVAAIIEDKDADEEQRRIHTVNTGILCAESTALRRWLSKLSNTNMQGEYYLTDIFASATADLTPANMIMVTDAQEVEGVNDLWQLTQLERAWQIRAARALCLQGARVADPARLDQRGTIRIGQNVHIDIDVVLEGEIELGDNVVIGPFVRLKNVKLGPGTKVHAHCDLEGVTTTGSALIGPFARLRPETMLADGVHIGNFVETKNTSIGADSKANHLTYLGDAQIGTKVNIGAGTITCNYDGVNKSITLIGDGAFIGSHSALIAPVSVGAGATLGAGTVLTHDAPAHQLTVARARQTTLDGWQRPKKKT
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_SHESR
Sequence: MKESVIRKLEGLLERNEEVLALLGDASVIADQERFRALSKEYSQLEEVVAGFKAYQQALADLESAKEMLEEDDAEMREMAQEEIKAAKAELERLEAELQILLLPKDPNDDTNAFIEIRAGAGGDEAAIFAGDLFRMYSRYAEANRWQLEIMSSNEGEHGGFKEIIVKVSGEGAYGKLKFESGGHRVQRVPETESQGRVHTSAVTVVVMHEVPEAEAISINPADLKVDTFRSSGAGGQHVNKTDSAIRITHIPTGIVVECQDQRSQHKNRAQAMSVLAARIQAVEDEKRRSAEESTRRSLVASGDRSERVRTYNFPQGRVSEHRINLTLYRLNEVMEGDLDAILGPLMQEHQADLLAALADEQG
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAU1_THEGJ
Sequence: MSTDTGVSVRVRGIYSTALTKLFLDRGFRISQPSQKIAERLGIEKTYDEFDVDIYDKRDHHGVILVGTEVEKVKEVFEEEFIDVLFRKLPYQLYGIYKGLVIKRDERYVYVDIGNAIGTIPVEEGKNLHEGDEVLVQVKKHNLLPHLSTMLTIPGDYAVLIPKPVGVQRHVKISRKIRDSSERERLRILGLSIDMGEWGILWRTAAAYKDWNTLRDEIIRLSKIADRLKEAEKKSAPEQIVEGRNIYEVEFGGGAKKKLDEIRNRVVPTVEGHHMLKAYDVEFSFAVEIAEGILAKVPGQRIKVNQGFWEALLDSKGPKKGWLFFLEHNKPDGQRYKLGPGEIVEVTFNPLRITLRRNLKPGKFYDGLDLPIEFGDYAITEIEAGKWWFVHRYYDRNGNLKGEYYNINTPVEIYPDRARYIDLEIDIVKWPDGEKEIIDKDKLREHYEDGIISEKLYKAVLRITQEVYERI
What is the function of this protein?
Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs.  Binds to RNA in loop regions with AU-rich sequences.
What are the official names of this protein?
Probable ribonuclease FAU-1, RNA-binding protein FAU-1.
What is the protein family that this protein belongs to?
Belongs to the FAU-1 family.
Protein: Y197A_STAAN
Sequence: MAMTVKKDNNEVRIQWRVADIKIPTSEIKNITQDQDIHAVPKLDSKDVSRIGSTFGKTNRVIIDTEDHEYIIYTQNDQKVYNELTK
What are the official names of this protein?
UPF0457 protein SA1975.1.
What is the protein family that this protein belongs to?
Belongs to the UPF0457 family.
Protein: SAHH_HERAR
Sequence: MNAAVMTSSTNFSDYVIADLSLSVWGDKEIRIAETEMPGLMAIREEFAAAQPLKGARITGSIHMTIQTAVLIQTLEALGAKVRWASCNIYSTQDHAAAAIAAAGTPVFAVKGETLDDYWEYTHRIFEWPNDDKGAPVYSNMILDDGGDATLLLHLGTRAEKDASVLNNPGSEEEICLFNSIKKHLAVDATWYSKRLPQILGVTEETTTGVHRLYQMHKEGKLAFPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMIAGKVAVIAGYGDVGKGSAQAMRALSAQVWVTEIDPICALQAAMEGYRVVTMDYAAEHGDIFVTCTGNYHVITHDHMAKMKDQAIVCNIGHFDNEIEVAALKQYTWENIKPQVDHIIFPDGKRIILLAEGRLVNLGCGTGHPSYVMSSSFANQTIAQIELYANTKNYPVGVYTLPKHLDEKVARLQLKKLNSQLTTLTDEQANYIGVQKAGPYKPEHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_CITK8
Sequence: MAKTIKITQTRSAIGRLPKHKATLLGLGLRRIGHTVEREDTPAVRGMVNAVSFMVKVEE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: LPPO_MYCTU
Sequence: MTDPRHTVRIAVGATALGVSALGATLPACSAHSGPGSPPSAPSAPAAATVMVEGHTHTISGVVECRTSPAVRTATPSESGTQTTRVNAHDDSASVTLSLSDSTPPDVNGFGISLKIGSVDYQMPYQPVQSPTQVEATRQGKSYTLTGTGHAVIPGQTGMRELPFGVHVTCP
What are the official names of this protein?
Putative lipoprotein LppO.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: UVRB_HELHP
Sequence: MGKFILDSQFAPAGDQPQAIQKITQFIHNGAQYSTLVGVTGSGKTYTMANIIANLNIPTLIMTHNKTLAAQLYSEFRGFFPKNHVEYFISHFDYYQPEAYIPRRDLFIEKDSSINEDLERLRLSATTSLLAYDDIIVIASVSANYGLGNPAEYLTMIHKFEIGQEEAQKTLLLKLVDMGYTRNDTIFERGNFRVNGEVIDIFPAYNEKEFIRIEFFGDEIERIGVFDALERTALTQLESFVLYAANQFIVGAQRLQSAIKNIEVELENRLEEFVSQDKQIEYQRLKTRTEFDLEMIKESGICKGIENYARHLTGKKAGETPYSLLDYFEQKGKPYLLIVDESHVSLPQFGGMYAGDRSRKEVLVEYGFRLPSALDNRPLRFDEFINKAPHFLFVSATPAQKELELSQEHIAEQIIRPTGLLDPLYEVRDADNAVLDLYDEIKARIAKNQRVLITTLTKKMAEELSKYYAELGIKVRYMHSDIDAIERNHLIRALRLGEFDVLIGINLLREGLDLPEVSLIAIMDADKEGFLRSETSLIQTMGRAARNVEGKVILYAKKITGSMQRAFEVTDYRRTKQEEFNRIHNITPKSVQRNVEQELKIESSGLSRLYEKASKKIPKSERESIIKELNIKMHQAAKALEFEEAARLRDEIARIRTM
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BL1S1_YEASB
Sequence: MFLTFSMCVNWIIVKMPNRSEELDRLLDKIINSPHRTEASKTLQEIENNQSYILNVQLKKLLRLHDDSFKNKCVSPINYMLEKYTPYMGHTEALQKEAELVDRDLRILEMTYQLIEKNRNSK
What is the function of this protein?
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1), a complex involved in endosomal cargo sorting.
What are the official names of this protein?
Biogenesis of lysosome-related organelles complex 1 subunit BLS1, BLOC-1 subunit BLS1, BLOS1-homolog.
What is the protein family that this protein belongs to?
Belongs to the BLOC1S1 family.
What are the subcellular locations of this protein?
Endosome.
Protein: SANA_SHIFL
Sequence: MLKRVFLSLLVLIGLLLLTVLGLDRWMSWKTAPYIYDELQDLPYRQVGVVLGTAKYYRTGVINQYYRYRIQGAINAYNSGKVNYLLLSGDNALQSYNEPMTMRKDLIAAGVDPSDIVLDYAGFRTLDSIVRTRKVFDTNDFIIITQRFHCERALFIALHMGIQAQCYAVPSPKDMLSVRIREFAARFGALADLYIFKREPRFLGPLVPIPAMHQVPEDAQGYPAVTPEQLLELQKKQGK
What is the function of this protein?
Participates in the barrier function of the cell envelope.
What are the official names of this protein?
Protein SanA.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: MVP_FBNY1
Sequence: MADTGYYAGYQDDVDVDEQKRHQALYLIGIILLVTVCLTVLWVCIMLACYVPGFLKKTLEAWLNSSSLMKRRVASTLTRTPFEATGPERERNWEARRQSTTVNPASQPNTGSVF
What is the function of this protein?
May transport viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier (By similarity).
What are the official names of this protein?
Putative movement protein, MP.
What is the protein family that this protein belongs to?
Belongs to the nanovirus movement protein family.
What are the subcellular locations of this protein?
Host cell membrane; Single-pass membrane protein. Note=The hydrophobic region is responsible for the localization of the protein to the cell periphery.
Protein: UBIC_SHESM
Sequence: MSVTSLSFPYGESIQWFCADNAKNLPSSPLKEWLLAPGSLTQKLKGCCDKFEVKILGEGQCVPLEGEYPKQNAVWVREVLLCLDSVPWVFARTLIPQSLLSTRQADFLGLGTRPLGELLFSQDSFVPGRIEIARFTTESRLAQLAQSLAQNVEHELWGRRRYFHHDQEEMFVSEMFLPAAVQAMAKLKLD
What is the function of this protein?
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
What are the official names of this protein?
Probable chorismate pyruvate-lyase, CL, CPL.
What is the protein family that this protein belongs to?
Belongs to the UbiC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMA_STRPJ
Sequence: MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIKEAGIKFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAAEQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERALPFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDEKLNVVSEYYLGK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: Y094_AFV1Y
Sequence: MLVEISNIYFMIATVVTVITSMYKIYRMMVRFIDNKIDSYLKPITEIQREEVEILRLIFATAPIKERKLYEQLDYDLKEIEKRLNDLNDSVNRH
What are the official names of this protein?
Uncharacterized protein ORF94.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: RL5_NEIMF
Sequence: MARLREFYKETVVPELVKQFGYKSVMEVPRIEKITLNMGVGEAVADKKVMEHAVSDLEKIAGQKPVVTVARKSIAGFKIRDNYPVGCKVTLRRDQMFEFLDRLITIALPRVRDFRGVSGKSFDGRGNYNMGVREQIIFPEIEYDKIDALRGLNITITTTAKTDEEAKALLSLFKFPFKG
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: RL36_STAES
Sequence: MKVRPSVKPICEKCKVIKRKGKVMVICDNPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: XYN5_ARATH
Sequence: MKNINNGFFLCMLLLLWCFVHSGISIDPFSPSDSLKTECVMKPPRSSETKGLLQFSRSVEDDSDEEWKIDGSGSIREMTQRIQLHEGNIYSFSAWVKLREGNNKKVGVVFRTENGRFVHGGEVRAKKRCWTLLKGGIVPDVSGSVDIFFESDDKEAKISASDVSLKQFSKQEWKLKQDQLIEKIRKSKVRFEVTYQNKTAVKGAVISIEQTKPSFLLGCAMNFRILQSEGYRNWFASRFKITSFTNEMKWYTTEKERGHENYTAADSMLKFAEENGILVRGHTVLWDDPLMQPTWVPKIEDPNDLMNVTLNRINSVMTRYKGKLTGWDVVNENVHWDYFEKMLGANASSSFYNLAFKLDPDVTMFVNEYNTIENRVEVTATPVKVKEKMEEILAYPGNMNIKGAIGAQGHFRPTQPNLAYMRSALDTLGSLGLPIWLTEVDMPKCPNQEVYIEEILREAYSHPAVKGIIIFAGPEVSGFDKLTLADKYFNNTATGDVIDKLLKEWQQSSEIPKIFMTDSENDEEEVSLLHGHYNVNVSHPWMKNMSTSFSLEVTKEMGQRQVVRVVINA
What is the function of this protein?
Binds to and hydrolyzes insoluble and soluble xylan substrates.
What are the official names of this protein?
Endo-1,4-beta-xylanase 5, AtXyn5, Xylan endohydrolase 5, Xylanase 5.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 10 (cellulase F) family.
Protein: RSBW_BACAC
Sequence: MMERFEKIEMKIPAKAEYVAIIRLTMAGVANRMGFAYDDIEDMKIAISEACTNIVQHAYKEDVGEIAIVFGLYENRLEIMVADNGVSFDFNNLRSKVGPYDISKPVEHLPENGLGLYLINTLMDDIQIMHDEGMTVLMTKYIQREQVENDGNPISTYESY
What is the function of this protein?
Negative regulator of sigma-B activity.  Phosphorylates and inactivates its specific antagonist protein, RsbV.  Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).
What are the official names of this protein?
Serine-protein kinase RsbW, Anti-sigma-B factor, Sigma-B negative effector RsbW.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-factor family.
Protein: RL22_VARPS
Sequence: MSETRAVLRGVRLSVDKGRLVADLIRGKKVDQALNVLQFTQKKAAVIIKKVLESAIANAEHNDGADIDELKVKTIYVEQGATLKRFTARAKGRGNRISKPTCHVYVTVGN
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: JAL41_ARATH
Sequence: MALMVNAKGGNGGKEWDDGFDYEGVTKIHVRAGSEGIQFIKFDYVKVGKTIDGPIHGVSGLGMTQTFEINHLQKEYLVSIEGYYDKSTGVIQSIQFKTNVKTSDMMGFNKGTKFSLGIIRNKIIGFHGFSDKNVYSLGAYFIKVLATKSGMQGGQNTGKSYDYGGDYDGIRKVYVTYDGTSIRHMRVDYDKAGQVECYEYGDKTGTQYKITVNYPYECITSVEGSYANTQPYGCIVLRSLTFKTSNGRTLVIGTVTGTKFLLESKGNAIVGFHGRVGSCVDSIGAYYAPFSPSPPPTQKLEGQGGDGGDSWDDGAFLNVKKVYIGQGSNGIVAVKFEYENDASEVVVGDEHGKTTLLGYEVFELDYPNEYITSLEGCHDKVMGAETGVITMLRFKTNKRTSPPFGLEAGVNFVLQKESHKITGFHGKSSTMLHQIGVHVVPITE
What are the official names of this protein?
Jacalin-related lectin 41.
What is the protein family that this protein belongs to?
Belongs to the jacalin lectin family.
Protein: RF1_HAES1
Sequence: MKASIISKLESLKERHEELEALLGEPSVINDQDKFRAYSKEYAQLEDVVKCFARWNWLNNNIEETQLLLDDPDMKEMAELEIEESKAEIENAEQQLQILLLPKDPNDEYNAYLEIRAGTGGDEAGIFAGDLFRMYSRYAESKRWRVEVLNANESEQGGYKEIIVKVNGEGVYGQLKFESGGHRVQRVPKTESQGRIHTSACTVAVMPELPENEMPEINPSDLRIDTYRSSGAGGQHVNTTDSAVRITHIPTGIVVECQDERSQHKNKAKALSVLASRIAQAEQERQAQAQADTRRNLLGSGDRSDKIRTYNYPQGRVTDHRINLTVYRLDEVMNGKIDELIQPIITEYQADQLAMLSEQN
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_METM6
Sequence: MYIFKIAYDGRLSFQTQPHGETVCDKISNALLDCGYLDNKDRVPLYHGGRTDRGVSALGNYIVYEMDKKPVLPRVQSKLKWDGVWVLGCKEIDTFPEIEYRHYQYNLPNKNHDVELMKKASEKLIGTHYFQNLSKRDKSKVKDPVRTLYNIKISSNDYFITIDIFGESFLWNMVRRIIRLLSDIGKHKIKDPEKFIELILSEDYSKGYPPSPAEGLILVDVKTNIDVDIDSYVLRMLKNSWEKSLNNSLMRLGLCKTVLSKT
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: PPA4_SCHPO
Sequence: MSQMSSASVKFPDSVPGVDYPKQLQLKYLQVIFRHGERAPVKERLGSAGIPKDWKLCNNARRFFAQIKGEKEWSVLGFERKVESPVDTSLAAPTSDNSPSGVCIHGELTDFGRVTTRTLGEYLRERYVKQLKFLPDELNNYADVYMRATPMVRALESLEHVFSGLYPESKRKMGLPVIFTRNWSDENLLPNENNCPRLVQLYEEFAERAAKLYDPLLAGRASEMMSQFMNGQPVRVVSSHPRLSGLLDTINAAIGSHVDFNPNLRDEQWLRDAETAVVEEWFGGYKVSKLMRQLGAGSLLNDLSMRMENFVVAEKNGSPYHRLALYGAHDVTIAAILASLDAFDYRWPPFTSHLEMELFEDTSSKSDSQNQSGDNKTTDLKLFSDESTDASNSAIVAASNSARDMSDWYVRITYNSTPVVMGACRGQGYKGNDTICPLSIFKDTVRALKPVEYHTMCKPVKK
What are the official names of this protein?
Probable acid phosphatase SPBC4.06.
What is the protein family that this protein belongs to?
Belongs to the histidine acid phosphatase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ETFA_MACFA
Sequence: MFRAAAPGQLRRAASSLRFQSTLVIAEHANDSLAPITLNTITAATRLGGEVSCLVAGTKCDKVAQDLCKVAGIAKVLVAQHDAYRGLLAEDLTPLILATQKQFNYTHICAGASAFGKNLLPRVAAKLEVAPISDIIAIKSPDTFVRTIYAGNALCTVKCDEKVKVFSVRGTSFEAAATSGGTASSEKASSTSPVEISEWLDQKLTKSDRPELTGAKVVVSGGRGLKSGENFKLLYDLADQLHAAVGASRAAVDAGFVPNDMQVGQTGKIVAPELYIAVGISGAIQHLAGMKDSKTIVAINKDPEAPIFQVADYGIVADLFKVVPEMTEILKKK
What is the function of this protein?
Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases, including acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase.  It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).  Required for normal mitochondrial fatty acid oxidation and normal amino acid metabolism.
What are the official names of this protein?
Electron transfer flavoprotein subunit alpha, mitochondrial, Alpha-ETF.
What is the protein family that this protein belongs to?
Belongs to the ETF alpha-subunit/FixB family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: CC14A_MOUSE
Sequence: MAAESGELIGACEFMKDRLYFATLRNRPKSTINIHYFSIDEELVYENFYADFGPLNLAMVYRYCCKLNKKLKSYSLSRKKIVHYTSFDQRKRANAAFLIGAYAVIYLKKTPEEAYRALLSGSNPPYLPFRDASFGNCTYNLTVLDCLQGIRKGLQHGFFDFETFDAEEYEHYERVENGDFNWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFKKNNVTTIVRLNKKIYEAKRFTDAGFEHYDLFFIDGSTPSDNIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQHFLKEKQASLWVQGDIFRSKLKNRPSSEGSITKIISTLDDMSIGANLSKLQSTERIGENNFEDEDMEIKNNVTQGDKLRALKSQRHPRSSPSCAFRSDDMKGHQRAMAQTFRLSSSPQPTMSTMKTSKVCLSPSVTAKKISRGSLSSGANIRSFSINSRLASSLGNLNAGTEEPETKKTTSLTKAAFIASPFTSFLNGSTQTPGRNYPELNNNQYTRSSNSNSSSSSSGLGGNLNSSPVPQSAKPEEHTTILRPSFPGSLSSSSVRFLSRSIPSLQSEYVHY
What is the function of this protein?
Dual-specificity phosphatase.  Required for centrosome separation and productive cytokinesis during cell division.  Dephosphorylates SIRT2 around early anaphase.  May dephosphorylate the APC subunit FZR1/CDH1, thereby promoting APC-FZR1 dependent degradation of mitotic cyclins and subsequent exit from mitosis (By similarity).  Required for normal hearing (PubMed:29293958).
What are the official names of this protein?
Dual specificity protein phosphatase CDC14A, CDC14 cell division cycle 14 homolog A.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Cell projection, kinocilium. Cytoplasm, cytoskeleton, spindle pole. Cell projection, stereocilium. Note=Centrosomal during interphase, released into the cytoplasm at the onset of mitosis. Subsequently localizes to the mitotic spindle pole and at the central spindle (By similarity). Present along both the transient kinocilia of developing cochlear hair cells and the persistent kinocilia of vestibular hair cells (PubMed:27259055).
Protein: RL6_XANAC
Sequence: MSRVAKKPVSLPKGVELNVQPGLVSVKGPKGTLTLPKPAGVEIAIDGGVATLSANDPSQIALTGTVRAILANMVKGVSEGFERKLELVGVGYRAAMQGKDLSLALGFSHPLVFVAPEGITLSTPTQTEIVVQGADKQRVGEVAAKIRGFRPPEPYKGKGVKYAGEVIIRKEAKKA
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RDRP_GGNNV
Sequence: MRRFEFALARMSGAAFCVYTGYRLLTSKWLADRVEDYRQRIIAEKKQILRDAAMIRTQIQREMELVRISVRKGHSHQEAATERNSATETMLGVVEKCGYEPYVISPSPREVGYHGSRQFYSLADFRQDYRRDDITDRHIIVMTDVDYYVDMHELIGLGVPILLYTFQPSTVSGEVKDGYFTITDDSVHYRVAGGKDVRHRIWNYNHDTMYVCSRPRGFWANLMQILRDITGVTAICSFLYTKLGIAPFGDPVTMFTVDQFKMGEHRNIVSIVPFATCRSNLLKISEYGAELEYMRYQQRNNIANFNAVTYISENGPLISLGLEGNFASVQLPLQDFENIRTAYELSKTNNLSDTVRRSGRPCKEAAIIHKCLQAECAVVSEVVHKPGDLARHYQAVGSAYDTDPAEQGKCYAREYAPGPLTQTAVFPSESRSNELATIDGRIAGPQAKAKSREHITPKMRKVARDFVHHLVPIAGTGRPYPLTYVEEQQTKPLQRARNDANRYHDEFTMMVKAFQKKEAYNAPNYPRNISTVPHTQNVKLSSYTYAFKASVLQHVPWYMPTHTPAEIADAVQNLAASSTELVETDYSKFDGTFLRFMRECVEFAIYKRWVHLDHLPELTTLLANEIQAPAVTRLGIKYDPDCSRLSGSALTTDGNSIANAFVSYLAGRMAGMDDDEAWSWIGIVYGDDGLRSGNVSNELLTNTASSLGFDLKIVNRAPRGSPVTFLSRVYLDPWSSPASVQSPLRTLLKLHTTCDTQSEIDDIGWAKTQAYLVTDSKTPFIGHWCRAYQRNCTARVVQYADYADIPFWVKNDDHVGNSWPQSESDDWNDIVANELGVTTAELLKHLALLDAYAGPISGLPRLTTSIDLEPKMSVALDGEIQAGPSQNKTSKDGTNPTSDRSAPRRARAALPGDDGHARRSRRSDRDPGKRDAHVRDKRPRRSSPPTRPVTPVPTPSSGDRGTDGDGLGRAAVRQRQRRRTQV
What is the function of this protein?
RNA-dependent RNA polymerase which replicates the viral genome composed of 2 RNA segments, RNA1 and RNA2.
What are the official names of this protein?
RNA-directed RNA polymerase, RdRp, RNA replicase, Protein A.
What is the protein family that this protein belongs to?
Belongs to the nodaviridae RNA polymerase family.