PharMolix/UniProtQA huggingface dataset:
Protein: YIDD_NITEU
Sequence: MKQLIIDLIKLYRYSIGLLIPPSCRFYPTCSNYMHEALVKHGLIKGLWLGMKRILRCHPWNQGGYDPVP
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: FLGA_RHIME
Sequence: MFRRSPGGKANMSGRAQPARAVLFAAMASCLLSPAAALAEPPTAVIPKQTIYPGEKLDASMLEVVDVTNPDLRDGYVRSIDEVDGMVTKRTLLPGRVILASALREQYAVERGSTVRLVFNNGGLTITAAGSPLQDAAVGDLIRVRNVDTGVIVSGTVMADSTIHVVAK
What are the official names of this protein?
Flagellar protein FlgA.
What is the protein family that this protein belongs to?
Belongs to the FlgA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: TRMB_PSEMY
Sequence: MTDTQQPELTEDGRQRRTIKSFVMRAGRMTEGQQRGLDKGWPLFGLELEDGLRDFDQVFGRSAPRTFEIGFGMGHSTLEMAAAAPEQDFIGVEVHKPGVGALLNGVMAHNLSNVRVYSCDALEVLQGCVADASLDRVLLFFPDPWHKSRHHKRRIVQPAFAELVRRKLKIGGVLHMATDWENYAEHMLEVMNAAPGYRNLAADGTYVPRPEERPVTKFERRGERLGHGVWDLKFQRQE
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: NDHI_RUDHI
Sequence: MFPMVTEFMNYGQQTVRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSIIDDYTIRTILNLPEIKT
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: CLPP_SHIFL
Sequence: MSYSGERDNFAPHMALVPMVIEQTSRGERSFDIYSRLLKERVIFLTGQVEDHMANLIVAQMLFLEAENPEKDIYLYINSPGGVITAGMSIYDTMQFIKPDVSTICMGQAASMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGYQGQATDIEIHAREILKVKGRMNELMALHTGQSLEQIERDTERDRFLSAPEAVEYGLVDSILTHRN
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_FRATO
Sequence: MIQMQTELQVADNSGAKRVECIKVLGGSHRRYASIGDVIKVTVKEASPRGKAKKGSVYNAVVVRTAKGVRRKDGSKVRFDGNAAVLLNANGQPIGTRIFGPVTRELRTEKFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: Y145_HERA2
Sequence: MADDRKALGRWGEQYAAEYLQQLGYQLIASGWHCRWGEIDLIAYDQATLVIIEVRTRRGTAHGSAAESLTLKKRQRLARLLQAYLQALDAAQTPWLGDYRIDAIAITLSRGQPQLEHFQAISIE
What are the official names of this protein?
UPF0102 protein Haur_0145.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: LHX5_RAT
Sequence: MMVHCAGCERPILDRFLLNVLDRAWHIKCVQCCECKTNLSEKCFSREGKLYCKNDFFRRFGTKCAGCAQGISPSDLVRKARSKVFHLNCFTCMVCNKQLSTGEELYVIDENKFVCKDDYLSSSSLKEGSLNSVSSCTDRSLSPDLQDPLQDDPKETDNSTSSDKETANNENEEQNSGTKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMKQLSALGARRHAFFRSPRRMRPLGGRLDESEMLGSTPYTYYGDYQSDYYAPGGNYDFFAHGPPSQAQSPADSSFLAASGPGSTPLGALEPPLAGPHGADNPRFTDMISHPDTPSPEPGLPGALHPMPGEVFSGGPSPPFPMSGTSGYSGPLSHPNPELNEAAVW
What is the function of this protein?
Plays an essential role in the regulation of neuronal differentiation and migration during development of the central nervous system.
What are the official names of this protein?
LIM/homeobox protein Lhx5, LIM homeobox protein 5, Homeobox protein LIM-2.
What are the subcellular locations of this protein?
Nucleus.
Protein: NAGZ_PSYIN
Sequence: MRPVILDVEGYELDSEEKEILAHPLVAGIILFTRNYYDIEQLKALVKDIRRYAGNELLIAVDHEGGRVQRFRDDFTRLPSAGSLIEKNDMKTACELAFSSAWVMASELIACDIDFSFAPVLDLNGISNVIQNRAFSSSITETVTLAEAYINGMKSAGMVSTGKHFPGHGSVEADSHTALPVDSRSELEIFTKDIKPFENLIKKGALDAVMPSHVVYSQCDLQPAGFSSYWLDDVLRTRLGFKGVVISDDLSMHGASFVGNHLSRAESAIQAGCDLILACNDRSGAVSILDNLKVKPTAQYHAVNQLRSTKNKFILPLNKNPIWIKNKQMLMQLSEQF
What is the function of this protein?
Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.
What are the official names of this protein?
Beta-hexosaminidase, Beta-N-acetylhexosaminidase, N-acetyl-beta-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROA_CITK8
Sequence: MESLTLQPIARVDGTINLPGSKSVSNRALLLAALASGTTVLTNLLDSDDVRHMLNALSALGVSYTLSADRTRCEITGQGGVLHAEGALELFLGNAGTAMRPLAAALCLGANDIVLTGEPRMKERPIGHLVDALRQGGAKIDYLEQENYPPLRLRGGFSGGHVEVDGSVSSQFLTALLMTAPLAPQDTTIAIKGDLVSKPYIDITLNLMKTFGVEVENQNYQRFVVKGEQQYRSPGQYLVEGDASSASYFLAAGAIKGGTVKVTGIGRNSMQGDIRFADVLEKMGATITWGDDFIACTRGELNAVDMDMNHIPDAAMTIATAALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDFIRITPPAQLQFAEIGTYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQLARISTPA
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSZ_STAAU
Sequence: MLEFEQGFNHLATLKVIGVGGGGNNAVNRMIDHGMNNVEFIAINTDGQALNLSKAESKIQIGEKLTRGLGAGANPEIGKKAAEESREQIEDAIQGADMVFVTSGMGGGTGTGAAPVVAKIAKEMGALTVGVVTRPFSFEGRKRQTQAAAGVEAMKAAVDTLIVIPNDRLLDIVDKSTPMMEAFKEADNVLRQGVQGISDLIAVSGEVNLDFADVKTIMSNQGSALMGIGVSSGENRAVEAAKKAISSPLLETSIVGAQGVLMNITGGESLSLFEAQEAADIVQDAADEDVNMIFGTVINPELQDEIVVTVIATGFDDKPTSHGRKSGSTGFGTSVNTSSNATSKDESFTSNSSNAQATDSVSERTHTTKEDDIPSFIRNREERRSRRTRR
What is the function of this protein?
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site.  The regulation of the ring assembly controls the timing and the location of cell division.  One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells.  Binds GTP and shows GTPase activity.
What are the official names of this protein?
Cell division protein FtsZ.
What is the protein family that this protein belongs to?
Belongs to the FtsZ family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane.
Protein: Y922_LIMRD
Sequence: MKRVWVTGYRSYELNIFKDNDPKVQVIKEVLKNYLRAQLELNDDEFWVITGPQMGTERWGLEAALELQADFPQLKTALMFPFAEFGKQWNENNQLKLTSITQQVDFFANVSDKPYQSPQQLRNYQQFMLTHTDEAFLLYDPEYQGKTKYDYEIIQKYKEESEYSMTFVDFDELQEEAEEWAERQREKDEF
What are the official names of this protein?
UPF0398 protein Lreu_0922.
What is the protein family that this protein belongs to?
Belongs to the UPF0398 family.
Protein: MED7A_XENLA
Sequence: MGEPQQVSALPIPPMQYIKEYTDENIRKSLAPKPPVPIKDSYMMFGNQFQCDDLIIRPLETQGIERLHPVQFDHKKELRKLLMSILVNFLDMLDILIRSPGSIRREEKLEDLKLLFVHMHHLINEYRPHQARETLRVMMEVQKRQRLETAERFQKHLERVVEMIQNCLASLPDDLPLPDGTVSVKTEPMDVQEPCTDHHEGPQGAAASVKEATIDKDAAMCGIIDEMT
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 7-A, Cofactor required for Sp1 transcriptional activation subunit 9-A, CRSP complex subunit 9-A, Mediator complex subunit 7-A.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 7 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACTB_RAT
Sequence: MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
What is the function of this protein?
Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells.  Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction.  In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.  Part of the ACTR1A/ACTB filament around which the dynactin complex is built.  The dynactin multiprotein complex activates the molecular motor dynein for ultra-processive transport along microtubules (By similarity).
What are the official names of this protein?
Actin, cytoplasmic 1, Beta-actin.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Nucleus. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Protein: RS12_STRPI
Sequence: MPTINQLVRKPRKSKVEKPKSPALNVGYNSHKKVQTNVSSPQKRGVATRVGTMTPRKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKDLPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RPOB_BARQU
Sequence: MAQTLAMTSQFNGRKRVRKFFGKIPEVTEMPNLIEVQKASYDQFLMIEEPKGGRPDEGLQAVFKSVFPISDFSGTAMLEFVGYEFDLPKFDVEECRQRDLTYAAPLKVILRLIVFDVDEDTGSKDIKDIKEQGVYMGDMPLMTTNGTFIVNGTERVIVSQMHRSPGVFFDHDKGKSHSSGKFLFAARVIPYRGSWLDIEFDAKDIIYARIDRRRKIPITSLLMALGMDASDILSTFYNKVTYERDGDGWRIPYSVGRFKGVKLISDLVDADSGEVVAEAGKKLTVRAAKALAEKGLKAVKITEDDLLGSYLAEDIVNYQTGEIYLEAGDEIDEKALKILFDVSADQINILDIDHMNIGAYIRNTLKVDKNESQQDALFDIYRVMRPGEPPTMDTAAAMFHSLFFDPERYDLSAVGRVKMNLRMDLDCPDTVRILRQEDILAVVKMLVELRDGRGEIDDIDNLGNRRVRSVGELMENQYRIGLLRMERAIKERMSSVEIDTVMPQDLINAKPAAAAVREFFGSSQLSQFMDQTNPLSEITHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGPNIGLINSLATFARVNKYGFIESPYRKIIDGKVTTEVIYLSAMEESKHYVAQANSSLDAEGRFTDEFVVCRHAGEVLMAPRDHVDLMDVSPKQLVSVAAALIPFLENDDANRALMGSNMQRQAVPLVRAEAPFVGTGMESIVARDSGAAVSAKRGGIVDQVDATRIVIRATEDLDPSKSGVDIYRLQKFQRSNQSTCINQRPLVHVGDRVEKGNIIADGPSTDLGDLALGRNVLVAFMPWNGYNYEDSILLSERIVADDVFTSIHIEEFEVAARDTKLGPEEITRDIPNVAEESLRNLDEAGIIYIGAEVQPGDILVGKITPKGESPMTPEEKLLRAIFGEKASDVRDTSMRMPPGAFGTVVEVRVFNRHGVEKDERAMAIEREEIERLAKDRDDEQSILDRNVYARLTDMLTGKIAVEGPKGFSKGKKLDNTIMGHYPRSQWWQFTVEDEKLQSEIEALRRQYDESKEALQRRFMDKVEKVQRGDEMPPGVMKMVKVFVAVKRKIQPGDKMAGRHGNKGVVSRILPIEDMPFLEDGTHADIVLNPLGVPSRMNVGQILETHLGWACAGMGKKIGDLVDLYQETGDIFPLRQRIENLMPDNDHNEPVRQYDNESLYKLALQMRKGVSIATPVFDGAHEADINMMLEDADLDSSGQVVLYDGRTGEPFDRPVTVGYIYMLKLHHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKVYEAIVRGDDTFEAGIPESFNVLVKEMRSLALNVELDDARELIAQRVLSDTTEQ
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: ISPD_PROMT
Sequence: MHLLIAAAGSGSRMGADRNKLLLKVAGKTVLEWTLKAAFEAKTISWIGIIGQPKDKNPICSILDNSVKAVQWINGGSTRQQSVQLGLAALPNDAKSVLIHDGARCLVRSFVFDEISKIVSKGQSVIAASQVTDTIKKVDIDGEIIESPPRSDLWAAQTPQGFPVNKLKHAHSEAISKGWNVTDDASLFERLGLPVKIYDAGPSNIKVTTPFDLVIAESLLSTLKD
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: U518_DROGR
Sequence: MSWLRTSPLRQSLTRNSGGNGSGGSGNSGNASATVRQRPIDAATDCDPRACYDSFCKHWQQAHEIIQHAGPPTHDDVLGVVSHLDYMVTLLLVELHHCNKVSLPTADAAPPTAPCLEYLLSENLLDKLYEWASTTGRYANAVRLEQLKLYELLVSHSRHQLLCHEPFLRPLLKILASSQGEIFPPDLEKRLVILLNQLCVVLMQNVHLLDLFFFSAQTQVQEQIQNGSLAAPKSGTTTNFIIFSLLIPYVHREGSLGHQARDALLLCMALSQKNSNIGHYIAQYSSICPLLVTGLGGLYSRLPNSIEVSAIDWHRITPDDVAEIPELTLFMNALEFCNAVVQVAHEMIKQQLLDFMYQGFIVPVLGPAILQTLKGKHFQTNIDSQISAMSYLDLILRSITEPGLMRAFVKFLLDTEKFDGERILDALVERLHSPDANLCMVTMALFDTLLGLHCEDLMLELLLKYMLPGKHVPISHRHKINKIDPYLNTTEFFLELTPDVMKRARDLARPKSVHELVDPGAALSSTMLPSLPSPVMSKTIGANWNYYGHYTGDSLYANIQAYLFEAHSRIAQCQRDCGKWANNYRYQKWPRQGQVRATSHALELARQFFSEFGTATPVAVAAVASSELGEKQLDSLQSIGESSGYESFKWRPDDADANDATTTTATSDPDVEHNNSSNHNNSSINSSGRRDLWRVSHSARNEILLTDLDFSEDLFAQGTVNLGPFLNAIWGKLQTFTSNSLYVNLHLTGLITRLAWYPLPLIHSLLLRSDIAITSDTPSFHQVLRMLKQQIDAELPVAENSLEIIDVARSSLIDREFRLINARKVSDNSPLHQQHHQQQQLQHTTNSTHQQQQAQQRSTYATLSAATPMHATPTSAYDPFRRSDNKRRSISASISNIFGRKSTSSTAAANPNPASSGLSQIYAFFTGAASTLVGGINGEVNSRGVAQENPRGNTCETSLSTTPRLDAQATSASSTNSSIGGSTQTLSATHSSSTLHGVESGPQTASFNSEPVSMDSVASMGIIANTSGTERSRDLALCAVLLDEWLKELAAIALEQSVVLVTEQLL
What are the official names of this protein?
FHIP family protein GH13096.
What is the protein family that this protein belongs to?
Belongs to the FHIP family.
Protein: FOLD_PSEF5
Sequence: MTAQLIDGKAIAASLRQQIAKRVAERRQQGLRTPGLAVILVGSDPASQVYVSHKRKDCEEVGFLSQAYDLPANTTQEDLAGLIDRLNDDPNIDGVLLQLPLPEHLDASLLLERIRPDKDVDGFHPYNVGRLAQRIPLLRPCTPKGIMTLLESTGADLYGMDAVVVGASNIVGRPMAMELLLAGCTVTVTHRFTKDLAGHVGRADLVVVAAGKPGLVKGEWIKEGAIVIDVGINRQDDGKLVGDVVYETALPRAGWITPVPGGVGPMTRACLLENTLYAAESLHS
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: TES_MUNMU
Sequence: MDLEAKVKKMGLGHEQGFGAPCLKCKEKCEGFELHFWRKICRNCKCGQEEHDVLLSNEEDRKVGKLFEDTKYTTLIAKLKSDGIPMYKRNVMILTNPVAAKKNVSINTVTYEWAPPVQNQALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPKEVKEMEQFVKKYKSEALGVGDVKLPRDMNTQGPNRMYIPGGDRSTTTAVGAMEDKSAEHKRTQYSCYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSACHELLVDMIYFWKNGKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDNILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVSYNNFSWHASTECFLCSCCSRCLIGQKFMPVEGMVFCSVECKKMMS
What is the function of this protein?
Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton.  Plays a role in the regulation of cell proliferation.  May act as a tumor suppressor (By similarity).
What are the official names of this protein?
Testin.
What is the protein family that this protein belongs to?
Belongs to the prickle / espinas / testin family.
What are the subcellular locations of this protein?
Cytoplasm. Cell junction, focal adhesion. Note=Detected along actin stress fibers.
Protein: RL29_PSEP1
Sequence: MKANELREKSAQQLNEQLLGLLRDQFNLRMQKATGQLGQSHLLSQVKRDIARVKTVLNQQAGK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: UBIG_BURO1
Sequence: MTNADPHELQKFSDLAHRWWDPNAEFKPLHDLNPVRLGWIDAHAHLAGKRALDIGCGGGILSESMAGLGAQVKGIDLSTEALGVADLHSLESGISVEYEAIAAEAIAAREPGTYDVVTCMEMLEHVPSPGDIVAACATLVKPGGWVFFSTLNRNLKSYLFAVIGAEYIAQMLPKGTHDYARFIRPSELASFVRATDLHIVEIKGITYHPIGKRFALSNDTDINYLVACRRGA
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: Y1299_STRPQ
Sequence: MVVKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGENIFCQITAVKRNFAEAKLLTVNKASKNRVKPACSVYETCGGCQIMHLAYPKQLDFKDDVIRQALKKFKPTGYEQFEIRPTLGMKKPDHYRAKLQFQLRSFGGTVKAGLFSQGSHRLVPIDNCLVQDQLTQDIINKITQLVDKYKLPIYNERKIAGIRTIMVRKAQASDQVQIIVVSSKEVRLANFIGELTKAFPQVKTVALNSNRSKSSEIYGDETEILWGQEAIHEEVLDYGFALSPRAFYQLNPQQTEVLYGEVVKALDVGSKDHIIDAYCGVGSIGFAFAGKVKSVRGMDIIPEAIEDAQKNAKAMGFDNAYYEAGKAEDIIPKWYKQGYRADAIIVDPPRTGLDDKLLKTILHYQPKQMVYVSCNTSTLARDLVQLTKVYDVHYIQSVDMFPHTARTEAVVKLQKRV
What are the official names of this protein?
Uncharacterized RNA methyltransferase SPs0562.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
Protein: HBZ_HTL1C
Sequence: MVNFVSVGLFRCLPVPCPEDLLVEELVDGLLSLEEELKDKEEEETVLDGLLSLEEESRGRLRRGPPGGKAPPRGETHRDRQRRAEEKRKRKKEREKEEEKQIAEYLKRKEEEKARRRKRAEEKAADFARRKQEEQERRERKWRQGAEKAKQHSARKEKMQELGVDGYTRQLEGEVESLEAERRRLLQEKEDLMGEVNYWQGRLEAMWLQ
What is the function of this protein?
Enhances viral infectivity and persistence, and facilitates proliferation of HTLV-1-infected lymphocytes (PubMed:16424388).  Mechanistically, inhibits Tax-mediated viral replication and NF-kappa-B activation (PubMed:18599479, PubMed:21552325).  Plays a role in allowing infected T-cells to escape the cytotoxic T-lymphocyte response by maintaining low levels of viral protein production.  Inhibits also host EP300 histone acetyltransferase (HAT) activity, reducing levels of acetylated histone H3 at 'Lys-18' (H3K18ac) in infected cells (PubMed:22434882).  Contributes to the accumulation of chromosomal abnormalities by inhibiting double-stranded DNA breaks (DSB) repair through the NHEJ pathway (PubMed:29769340).  Participates in the modulation of host immune response at multiple levels contributing to abnormal interferon signaling and viral pathogenesis (PubMed:28768861).
What are the official names of this protein?
HTLV-1 basic zipper factor, HBZ.
What is the protein family that this protein belongs to?
Belongs to the HTLV-1 HBZ protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: VSPR_VIBCH
Sequence: MRRSMKISAEMYKLLIERTLDGFSVIELRDEFIVIKDSLIDPDEAYKKVYRQILRFIKKGWLNGEGSGRQKRYFQTDTFKALHAEPKSENVDIEIVLNQDYSVLVSERNQYKGELEIVLGEIDEYQSLNIRFPELEPKLITLLDEAKERSACLLGKVNGLTNVLKVLSGQKIVHQKFKTKALLFERT
What is the function of this protein?
Represses the transcription of several genes encoded within the Vibrio 7th pandemic island-1 (VSP-1), including dncV, VC_0176, VC_0178 and VC_0180.
What are the official names of this protein?
Transcriptional regulator VspR, V.cholerae 7th pandemic regulator, VSP-1 transcription factor VspR.
Protein: RBL_TETOB
Sequence: MVPQTETRAGAGFKAGVKDYRLTYYTPDYVVKDTDILAAFRMTPQPGVPPEECGAAVAAESSTGTWTTVWTDGLTTLDRYKGRCYDIEPVPGEDNQYIAYVAYPIDLFEEGSVTNLFTSIVGNVFGFKALRALRLEDLRIPPAYVKTFQGPPHGIQVERDKLNKYGRGLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFVAEATYKAQSETGEIKGHYLNATAATCEEMLKRAQCAKELGVPIIMHDYLTGGFTANTSLSSYCRDHGLLLHIHRAMHAVIDRQRNHGIHFRVLAKALRLSGGDHLHSGTVVGKLEGEREVTLGFVDLMRDDYIEKDRSRGIYFTQDWCSMGGTMPVASGGIHVWHMPALVEIFGDDACLQFGGGTLGHPWGNAPGAVANRVALEACTQARNEGRDLAREGGDVIRSACKWSPELAAACEVWKEIKFEFETIDKL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PGMB_ASPTN
Sequence: MLTKRRMKFQYISCLAWLAHYDIFHLVPRDKNISYADLARAAGVPEQRLKSILRMAMTSSLFREHPNGTDVGHSAVSALLASDDDAYSYATYMCSKTAPMAMSMTEAHKRWGASTRTNETAYNVAFNTDLPFFDYLAQNKARMDEFARYMRSVRSSETVALKHLISGVDWESIPAGGMLVDVGGSTGGAAIALAQAYPHIRFTVQDLPENVETGEKAAAASLPADIASRLTFQAHDFTLPQPVRAADAYLLRMILHDWPDEQAVKILRNIVTAMDETKSRLFIMDTVLPKPGSVPISVERIARARDLTMIQSFNSKERELDEWKDLITAADPRLQLIGVTQPFGSAMSILEIQLSAK
What is the function of this protein?
O-methyltransferase; part of the gene cluster that mediates the biosynthesis of pleosporalin A, ascomycone A, as well as a third cryptic naphthoquinone derived pigment, all responsible for the coloration of conidia (PubMed:28471414, PubMed:35351612).  Specifically methylates position C-6 of the pgmA product 3-acetonyl-1,6,8-trihydroxy-2-naphthaldehyde to yield fusarubinaldehyde (PubMed:35351612).  The pathway begins with the biosynthesis of the cyclized heptaketide 3-acetonyl-1,6,8-trihydroxy-2-naphthaldehyde by the NR-PKS pgmA.  The C-6 hydroxyl group is further methylated by the O-methyltransferase pgmB to yield fusarubinaldehyde which is in turn oxidized by the cytochrome P450 monooxygenase pgmC at C-9.  The C-1 hydroxyl group is then methylated spontaneously.  Although pgmE, pgmD and pgmH are essential for the production of pleosporalin A, it is not the case for the 2 other final products and it remains difficult to assign a specific function to each enzyme.  PgmF and pgmG seem not to be involved in pigment biosynthesis although they were regulated by the cluster-specific transcription factor pgmR (PubMed:35351612) (Probable).
What are the official names of this protein?
O-methyltransferase pgmB, Pigmented naphthoquinones biosynthesis cluster protein B.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.