PharMolix/UniProtQA huggingface dataset:
Protein: EXOS_PSEAE
Sequence: MHIQSLQQSPSFAVELHQAASGRLGQIEARQVATPSEAQQLAQRQDAPKGEGLLARLGAALVRPFVAIMDWLGKLLGSHARTGPQPSQDAQPAVMSSAVVFKQMVLQQALPMTLKGLDKASELATLTPEGLAREHSRLASGDGALRSLSTALAGIRAGSQVEESRIQAGRLLERSIGGIALQQWGTTGGAASQLVLDASPELRREITDQLHQVMSEVALLRQAVESEVSRVSADKALADGLVKRFGADAEKYLGRQPGGIHSDAEVMALGLYTGIHYADLNRALRQGQELDAGQKLIDQGMSAAFEKSGQAEQVVKTFRGTRGGDAFNAVEEGKVGHDDGYLSTSLNPGVARSFGQGTISTVFGRSGIDVSGISNYKNEKEILYNKETDMRVLLSASDEQGVTRRVLEEAALGEQSGHSQGLLDALDLASKPERSGEVQEQDVRLRMRGLDLA
What is the function of this protein?
Bifunctional effector protein that is secreted and delivered by the type III secretion system into eukaryotic target cells (PubMed:15252013).  The N-terminus encodes a GTPase-activating protein activity, whereas the C-terminus encodes an ADP-ribosyltransferase activity.  ADP-ribosylates several eukaryotic proteins including ezrin/radixin/moesin (ERM), cyclophilin A and several members of the Ras superfamily (PubMed:9516428, PubMed:15252013).  Host Ras ADP-ribosylation blocks its activation by its guanine nucleotide exchange factor, thereby interfering with Ras-mediated signal transduction (PubMed:10419499).  For instance, prevents Ras from interacting with and activating phosphoinositol-3-kinase (PI3K), which is required to stimulate the phagocytic NADPH-oxidase that generates reactive oxygen species (PubMed:28494242).  The ADPRT domain contributes also to bacterial dissemination to the blood during pneumonia (PubMed:26090668).  In addition to this activity, acts via its N-terminal region as a GTPase-activating protein (GAP) for host Rho GTPases including RhoA, Rac1, Cdc42 and Ras (PubMed:10593930).  The GAP domain activity induces mitochondrial disruption in the target host cell by activating host caspases 3 and 9 that execute cellular death (PubMed:30232373).
What are the official names of this protein?
Secreted exoenzyme S.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the Arg-specific ADP-ribosyltransferase family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via type III secretion system (T3SS) and delivered into the host cytoplasm.
Protein: RS2_ALKCK
Sequence: MAVISMKQLLEAGVHFGHQTRRWNPKMDRYIFTERNGIYIIDLQKTVKKVETAYNFVRDLAADGGKILFVGTKKQAQDSVRDEAIRCGMYYINQRWLGGTLTNFETIQKRITRLKNLEKMQEDGTFDVLPKKEVILLKKEMDRLEKFLGGIKDMNGVPDALFVIDPRKERIAIAEAHKLNIPIVAIVDTNCDPDEIDYVIPGNDDAIRAVKLLTGKMADAVIEATAGESEEEVDVEEETTTA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RS7_MESFL
Sequence: MRKNRAEKRDVLADPIYNSKLVTRAINKIMLDGKRGTAQTIIYDAFDIIKEKTGEEPIEIFNKAIENIKPHLELKVRRIGGANYQVPVEVSDERQVTLALRWLINYARLRNEKVMTVKLANEIIDASNNMGGSVKKREDTHKMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: Y1648_AERPE
Sequence: MKCWTLGDRVLAVSMGDLTKVRAEAVVNPANSLMIMGGGAAGALKRAGGSVIEEEAMRKAPVPVGEAVITSGGSLPARFVIHAPTMEEPGMRIPLVNAFKASYAALRLASEAGIESVAMPAMGAGVGGLSVAEVAREAAMAASILRGKWPRYIILVARGEEAYRGMEKGVREALGVEGGECPADLARLV
What are the official names of this protein?
Uncharacterized protein APE_1648.1.
Protein: QUEA_HELPG
Sequence: MKEFDLESYDYYLPKELIANYPVLPKEKAKLLVYERRSQTITHTTFEHVLDFFPKNALIVLNDTKVMKARLFGSKHAFLPSKTTEVFFHRFFKDNTALTQIKGKIKVGDKIFFDENYYAEVLELLHNGQRLIAFYDNQTPLNQENILKLLEQYGHMPLPPYIKRADESLDAHEYQSVFAKHTGAVAAPTASLHFSQHGLEKLLKDFKHAFLTLHVGAGTFLGVETKDIREHQIHTEVLRIPKKSQEILQKSQEILCIGTTALRSVEYFKRLENPNQEAFECDIFLHLANPILHVNYLLTNFHLPKSSLLMLVSAMIGLEKTKEIYKIAIEKKYRFYSYGDGMLIL
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSRP_SHEB2
Sequence: MAPKVFYISDGTAITAEVFGHAVLSQFPLEFESLTIPFVETLTKAEQVKRQINDCFITTGERPLVFHSIVKAEIRDIIYSSEGLDYDFLNTFVAPLEQHLGVSASPVLHRTHGKANHGYEARIDAINFAMDNDDGQTMKHMDQADLVLLGVSRCGKTPSSLYLSMQFGIKAANYPFTEDDMDNLKLPDALKRNKKKLFGLTIDPVRLHEIRQSRMENSRYSSLKQCRLEVKEVEMLFKRERIPYIDTTNHSVEEIATKILDVTGLERHMF
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: LIPS_HUMAN
Sequence: MEPGSKSVSRSDWQPEPHQRPITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQETPAQHDAESQKEPRAQQKSASQEEFLAPQKPAPQQSPYIQRVLLTQQEAASQQGPGLGKESITQQEPALRQRHVAQPGPGPGEPPPAQQEAESTPAAQAKPGAKREPSAPTESTSQETPEQSDKQTTPVQGAKSKQGSLTELGFLTKLQELSIQRSALEWKALSEWVTDSESESDVGSSSDTDSPATMGGMVAQGVKLGFKGKSGYKVMSGYSGTSPHEKTSARNHRHYQDTASRLIHNMDLRTMTQSLVTLAEDNIAFFSSQGPGETAQRLSGVFAGVREQALGLEPALGRLLGVAHLFDLDPETPANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRTSHNLAELEAYLAALTQLRALVYYAQRLLVTNRPGVLFFEGDEGLTADFLREYVTLHKGCFYGRCLGFQFTPAIRPFLQTISIGLVSFGEHYKRNETGLSVAASSLFTSGRFAIDPELRGAEFERITQNLDVHFWKAFWNITEMEVLSSLANMASATVRVSRLLSLPPEAFEMPLTADPTLTVTISPPLAHTGPGPVLVRLISYDLREGQDSEELSSLIKSNGQRSLELWPRPQQAPRSRSLIVHFHGGGFVAQTSRSHEPYLKSWAQELGAPIISIDYSLAPEAPFPRALEECFFAYCWAIKHCALLGSTGERICLAGDSAGGNLCFTVALRAAAYGVRVPDGIMAAYPATMLQPAASPSRLLSLMDPLLPLSVLSKCVSAYAGAKTEDHSNSDQKALGMMGLVRRDTALLLRDFRLGASSWLNSFLELSGRKSQKMSEPIAEPMRRSVSEAALAQPQGPLGTDSLKNLTLRDLSLRGNSETSSDTPEMSLSAETLSPSTPSDVNFLLPPEDAGEEAEAKNELSPMDRGLGVRAAFPEGFHPRRSSQGATQMPLYSSPIVKNPFMSPLLAPDSMLKSLPPVHIVACALDPMLDDSVMLARRLRNLGQPVTLRVVEDLPHGFLTLAALCRETRQAAELCVERIRLVLTPPAGAGPSGETGAAGVDGGCGGRH
What is the function of this protein?
Lipase with broad substrate specificity, catalyzing the hydrolysis of triacylglycerols (TAGs), diacylglycerols (DAGs), monoacylglycerols (MAGs), cholesteryl esters and retinyl esters (PubMed:8812477, PubMed:15955102, PubMed:15716583, PubMed:19800417).  Shows a preferential hydrolysis of DAGs over TAGs and MAGs and preferentially hydrolyzes the fatty acid (FA) esters at the sn-3 position of the glycerol backbone in DAGs (PubMed:19800417).  Preferentially hydrolyzes FA esters at the sn-1 and sn-2 positions of the glycerol backbone in TAGs (By similarity).  Catalyzes the hydrolysis of 2-arachidonoylglycerol, an endocannabinoid and of 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor (By similarity).  In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production (By similarity).
What are the official names of this protein?
Hormone-sensitive lipase, HSL, Monoacylglycerol lipase LIPE, Retinyl ester hydrolase, REH.
What is the protein family that this protein belongs to?
Belongs to the 'GDXG' lipolytic enzyme family.
What are the subcellular locations of this protein?
Cell membrane. Membrane, caveola. Cytoplasm, cytosol. Lipid droplet. Note=Found in the high-density caveolae. Translocates to the cytoplasm from the caveolae upon insulin stimulation (PubMed:17026959). Phosphorylation by AMPK reduces its translocation towards the lipid droplets (By similarity).
Protein: RRF_THEPX
Sequence: MSDYLKASEEKMQKSLSVLKNELAAIRAGRANPALLDRIMVDYYGTPTPLNRLATITAPEPRVLVVQPWDVSKISDIEKAIQKSDLGINPVSDGKVLRLVFPELTEERRKELVKLVHKKAEEAKVAVRQIRRDANDAVKKMEKNGEISEDERKKREEEIQKLTDKYIKEIDKVVEAKEKEIMEI
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPO11_SULIY
Sequence: MEIKILKSERNYLELEIEGEDHTLGNLIAGTLRKISGVSFASYYQPHPLTDKIIVKILTDGSIAPKDALLKAIETVRVMASHYIDEIKGLSK
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo11, DNA-directed RNA polymerase subunit L.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS5_LISMF
Sequence: MPEQIDGNKLDLEERVVTINRVAKVVKGGRRFRFTALVVVGDKNGHVGFGTGKAQEVPDAIRKAVEDAKKNMVLVPTVDTTIPHTVVGHFGGGEILLKPASAGSGVTAGGPVRAVLELAGVADVSSKSLGSNTPINMVRATIDGIKQLKNAEDVAKLRGKTVEELLG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: WIPF2_MOUSE
Sequence: MPIPPPPPPPPGPPPPPTFNQANTEQPKLSRDEQRNRGALLQDICKGTKLKKVTNVNDRSAPVIEKPRGSSGGYGPGAAALQPKGGLFQGGVPKLRPVGAKDASEAPAGKPALQVPSSRAAAPRPPGSAASGRPHDDTDSNRASLPELPRMQRPSLPDLSRPNTASGTGMKHSSSAPPPPPPGRRANAPPTPLPLHSNKAQAYNREKPLPPTPGQRLHPGREGHPAPPPVKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPTNESAPELPQRHNSLHRKTPGPVRGLAPPPPTSATPSLLSNRPPPPAREPPSRGAAPPPPPPMIRNGARDAPPPPPPYRMHGSEPPSRGKPPPPPSRTPAGPPPPPPPPLRNGHRDSITTVRSFLDDFESKYSFHPVEDFPAPEEYKHLQRVYPSKTNRAARGAPPLPPILR
What is the function of this protein?
Plays an active role in the formation of cell surface protrusions downstream of activated PDGFB receptors.  Plays an important role in actin-microspike formation through cooperation with WASL.  May cooperate with WASP and WASL to induce mobilization and reorganization of the actin filament system (By similarity).
What are the official names of this protein?
WAS/WASL-interacting protein family member 2, WASP-interacting protein-related protein, WIP-related protein.
What is the protein family that this protein belongs to?
Belongs to the verprolin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Localized to stress fibers and bundles of actin filaments.
Protein: PUX11_ARATH
Sequence: MEALSSLTFKGSLPEAIFEAKGKKKLFVVYISGEDEESDKLNRLTWTDASVADSLSKYCILVHIQAGSVDATNFSAIYPYSSVPCIAAIGFSGTQVWRTEGFITAEDLASSLEKAWLGLHIQETTASIFSAALASQNSETPVSSASSVVLPPGSVPLDAAVASPSTASSVQPSETKSTVTSASTTENNDGTVAVKGKESAEPSNLCDTTKNQPAPSVDGTKANVEHEATETPLRVQAEKEPIRPTAPGTNDNTSRVRSSVDRKRKQGTVINEEDSGVGVSGRDINLTKSVDTKETMKPKDEGGEEEDGEKSKKASDVHLNIRLPDGSSLQEKFSVTSILRMVKDYVNSNQTIGLGAYDLAVPYPRKVYTDQDLDKSLSELRLFDRQALVVVPRKRATVYQRGTSYSESNNNTDPNSGGYFAYVRRVLSYANPFSYFGGGTANASSSVPERQTRPNTEVRNNLGQVGTSFQDPSEGRSNVRNRRPTTSRIGSNIHTLNHNEDEAPFGDGNAFWNGNSTQYGGGSGGDSNDRR
What are the official names of this protein?
Plant UBX domain-containing protein 11, PUX11, CDC48-interacting UBX-domain protein 11.
Protein: RL30_GEOMG
Sequence: MSAGLKITLIKSQIGAPTAQKAVLNGMGLNKLNKTVVLKNTPEIVGMIAKVSHMVKVEE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: RRP36_PODAN
Sequence: MSSVKRKQPPATLLQRRVRPRYEPEPESDVEEMSDAPSEEGAGFDSEDEEMSEAEMRSGSDEENSELGSDPEDGEDESEDDTPQPTHQLSFGALAKAQAALGDKLNKRKRRSSSAASEASSSRDNSNNDNKFSLEKNHKKPLEKPSRTSKHAPVELSSKRQVSRRRDFLLDPTSTKPQHRDPRFFAPSTMSATSKIDEIKARKAYAFLDEYREKEMQELRVAIKKSKNAEEKEKLQKALLSMESKKKAQERKDKAQKVLDEHKKKEKELVRQGKNPFYLKRSEQKKRVVVETFKGMKKGQVDRAIERRRKKVAGKEKKLLPWARRTVEDR
What is the function of this protein?
Component of the 90S pre-ribosome involved in the maturation of rRNAs.  Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity).
What are the official names of this protein?
rRNA biogenesis protein RRP36, Ribosomal RNA-processing protein 36.
What is the protein family that this protein belongs to?
Belongs to the RRP36 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ACSL1_CAVPO
Sequence: MQAHELLQYFRLPELVDIRQYVRTLPTNTLMGFGAFAALTTFWYATRPKALKPPCDLSMQSVEVAGSDGARRSTLLDSDEPLVYFYDDVRTLYDVFQRGIQVSNNGPCLGSRKPDQPYEWLSYKQVEDLSECIGSALLQKGFQASPDQFIGIFAQNRPEWVIIEQACFAYSMVVVPLYDTLGADAITYIVNKAELSVIFADKPEKARILLESVENKLTPGLKIIVVMDSYGSELVEQGKKCGVEVISLKAMEGLGRANRRKPKPPEPDDLAVICFTSGTTGNPKGAMITHKNVVSDCSAFVKATEKALVLNASDIHISFLPLAHMYEQLLQCVMLCHGAKIGFFQGDIRLLMDDLKALQPTIFPVVPRLLNRMFDRIFAQANTTVKRWLLDFASKRKEAELRSGIIRNNSVWDKLIFHKIQSSLGGKVRLMVTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCSLSVPGDWTAGHVGAPMPCNFIKLVDVEEMNYMAAMGEGEVCVKGPNVFKGYLKDPAKTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYVRSEPVAQVFVHGESLQAFLIAIVVPDAESLASWARKRGFEGSFEELCRNKDVKKAILEDMVRIGKDSGLKSFEQVRGIALHPELFSVDNGLLTPTMKAKRPELRNYFRSQIDELYSTIKV
What is the function of this protein?
Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation (By similarity).  Preferentially uses palmitoleate, oleate and linoleate (By similarity).  Preferentially activates arachidonate than epoxyeicosatrienoic acids (EETs) or hydroxyeicosatrienoic acids (HETEs).
What are the official names of this protein?
Long-chain-fatty-acid--CoA ligase 1, Arachidonate--CoA ligase, Long-chain acyl-CoA synthetase 1, LACS 1, Palmitoyl-CoA ligase, Phytanate--CoA ligase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Microsome membrane; Peripheral membrane protein. Mitochondrion outer membrane; Peripheral membrane protein. Peroxisome membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: AROK_RHOPA
Sequence: MPRMSETVPTAAAGRSPQEAEIVAALGDRPVVLIGMMGAGKSTVGRRLALRLGLPFLDADTEIESAAAMTIPEIFETHGEPHFRDGEARVISRLLDGGTKVLATGGGAFMREETRDRIREKAISMWLEAEADVILRRVKRRADRPLLKTPDPAGTIARLIAERYPLYREADITIASRDVPHEKIVDECVAALHDYLCAAPPQP
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 5HT6R_PANTR
Sequence: MVPEPGPSANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNTSNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTPPRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQCRLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVPRTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPGLFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGPRPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATRDPPLPTRAAAAVNFFNIDPAEPELRPHPLGIPTN
What is the function of this protein?
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen.  The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.  It has a high affinity for tricyclic psychotropic drugs (By similarity).  Controls pyramidal neurons migration during corticogenesis, through the regulation of CDK5 activity (By similarity).  Is an activator of TOR signaling (By similarity).
What are the official names of this protein?
5-hydroxytryptamine receptor 6, 5-HT-6, 5-HT6, Serotonin receptor 6.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ULAR_SALPB
Sequence: MTEAQRHQILLDMLAQLGFVTVENVIERLGISPATARRDINKLDESGKLKKVRNGAEAITQQRPRWTPMNLHQAQNHDEKVRIAKAASQLVNPGESVVINCGSTAFLLGREMCGKPVQIITNYLPLANYLIDQEHDSVIIMGGQYNKSQSITLSPQGSENSLYAGHWMFTSGKGLTADGLYKTDMLTAMAEQKMLSVVGKLVALVDSSKIGERAGMLFSRADQIAMLITGKNANPQVLQQLEAQGVSILRV
What is the function of this protein?
Represses ulaG and the ulaABCDEF operon.
What are the official names of this protein?
HTH-type transcriptional regulator UlaR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CC196_HUMAN
Sequence: MTSGANSSGSYLPSEIRSSKIDDNYLKELNEDLKLRKQELLEMLKPLEDKNNLLFQKLMSNLEEKQRSLQIMRQIMAGKGCEESSVMELLKEAEEMKQNLERKNKMLRKEMEMLWNKTFEAEELSDQQKAPQTKNKADLQDGKAPKSPSSPRKTESELEKSFAEKVKEIRKEKQQRKMEWVKYQEQNNILQNDFHGKVIELRIEALKNYQKANDLKLSLYLQQNFEPMQAFLNLPGSQGTMGITTMDRVTTGRNEHHVRILGTKIYTEQQGTKGSQLDNTGGRLFFLRSLPDEALKN
What are the official names of this protein?
Putative coiled-coil domain-containing protein 196, Long intergenic non-protein coding RNA 238.
Protein: GLUQ_ALKCK
Sequence: MNQLRGRFAPTPSGELHLGNLYVALLSWLQVRQGGGQFILRMEDIDRPRSRNELVGPMMDDLHWLGLDWDEGPDQGGENGPYYQSKRLHLYEEALHNLQQQQLLYHCYCSRAELQAVASAPHGVASEGQAYPGTCKKLTAAERAAKAAKKTPSLRFAVDKGPTAEKMDVEMEKLLRRGGDFVVQRADGIISYQLAVVVDDALMGITDVLRGQDLYDSTPRQLLLYAALGYTAPRFVHVPLLYGPDGRRLAKRHRDLSLAAIRANGCRPENIVGLLAALSGLIERPEPLTAAELIPEFRLEKLTTEPILLDTHLLQLLN
What is the function of this protein?
Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp).  Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.
What are the official names of this protein?
Glutamyl-Q tRNA(Asp) synthetase, Glu-Q-RSs.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
Protein: RS19_MOOTA
Sequence: MGRSLKKGPYCDAKLLKKIIDMNEKGEKRVIKTWSRRSTIFPEMVGHTIAVHDGRKHVPIYITEDMVGHKLGEFAPTRVFRGHGAHTERSTALK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: PKHH1_HUMAN
Sequence: MAELKVEAPASVDWQKRCLTLETQLFRFRLQASKIRELLADKMQELEQRLLEAEQRAENAETQVGVMEEKVKLSNLKNVDSEGSLHRKYQELLKAIKGKDELISQLEAQLEKQKQMRAEEAKTVQEKAAKIKEWVTLKLAKLEMENQHLKSHNQRLVEQVGSLQDALEAIQIAPSRKLLVPPYGAAEQDSVPSEPGIQPMGQDSGSQAQGLKAAVLAPSPGALQSKDSVSEAASPLEDSSSSTVHSGETVEAKPLQPHLGRESPPHQPCMKLLTFRCSSASWGEGLVTAQRGMLPGTKTSAREGGPGSSLTLPKVRAPGTPRDSIQLAKRHHSQPQVGHGHFGRVVNIETEAFSALHPSGLPELESRARSREEPEKMEMEEPPPAGKNEERESPKALGAELEEVELGNKPPTPPLHQFSSWESRIYAVATSGMRLSDMSPRSNTACCASSPPALVSPGSFSGLVYKNVTVPVYTALKGRATQISNMPFMDESSGSDDDCSSQASFRISVPSSESRKTSGLGSPRAIKRGVSMSSLSSEGDYAIPPDACSLDSDYSEPEHKLQRTSSYSTDGLGLGGESLEKSGYLLKMGSQVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQGQVDLNSRCQIVRGEGSQTFQLISEKKTYYLTADSPSLLEEWIRVLQSLLKVQATGPPALLRGGTKPTVKGWLTKVKHGHSKVVWCALVGKIFYYYRSHEDKRPLGCLPVRDAHIEEVDRSCDSDEDYEAGGTRRLLSSHCTLVIHPTEHSPTYLLIGTKHEKDTWLYHLTVAAGGSSAKVGTAYEQLIGKLMDGEGDPDSPLWRHPMLCYSKDGLYASLTTLPSEALQTEALKLFKSCQLFINVPVEAASVDYHVSLAQTALQVCLVHPELQSEIYCQLMKQTSCRPPQKYSLMQCWQLLALCAPLFLPQHHFLWYVKQQLQRHADPRSETGQYATYCQRAVERTLRTGEREARPSRMEVVSILLRNPFHHSLPFSIPVHFTNGTYHVVGFDGSSTVDEFLQRLNQEIGMRKPSHSGFALFTDDPSGRDLEHCLQGSVKICDAISKWEQAMKELHPGKSEGGTRVVKLMYKNRLYFRSQVKGETDRERLLLASQTSREIVAGRFPINKELALEMAALMAQVEYGDLEKPALPGPGGTSPAKAQHLLQQVLDRFHPRRYRHGAPAEQLRHLADMLTTKWATLQGCSPPECIRIYLTVARKWPFFGAKLFAAQPAQLSSKENALVWIAVNEDGVSILDHNTMQVHITYPYSSVTTFGGCRDDFMLVIRSIPDKSSGKSHIEKLIFRMAAPKIAEATFIMASYMNHCTTTVNPPTNPPGACQLWELDGRQFFSSVSCATKGPTLL
What are the official names of this protein?
Pleckstrin homology domain-containing family H member 1, PH domain-containing family H member 1.
Protein: UL17_HCMVA
Sequence: MDHALFTHFVGRPRHCRLEMLILDEQVSKRSWDTTVYHRRRKHLPRRRAPCGPQRPAEIPKRRKKAAVLLFWHDLCWLFRRLFFPREDSEPLMSDPARSPEEEE
What are the official names of this protein?
Uncharacterized protein UL17.
Protein: HIS1_SODGM
Sequence: MLDKSRLRIAMQKSGRLSKESQQLLEQCGIKINLQQQRLLAFAENMPIDIMRVRDDDIPGLVMDDVVDLGIIGENVLEEELLTRRAQGEDPRYFTLRQLDFGGCRLSIALLLDTPWTGPECLRGKRIATSYPHLLKQYLDKLDITFKSCLLNGSVEVAPRAGLADAICDLVSTGATLEANGLREAEVIYRSKACLIQRDGELSVAKQSLVDKLLIRIQGVIQARESKYIMMHAPTERLDDIISLLTGAEQPTILPLAGDQHRVAMHMVSSETLFWETMENLKALGASSILVLPIEKMME
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADAM2_MACFA
Sequence: MWRVLFLLSGLGGLWMDSNFDSLPVQITVPEKIRSIIKEEIESQVSYKIVIEGKPYTANLMQKNFLSHNFRVYSYNGTGIMKPLDQDFQNFCHYQGYIEGYPKSVAMVSTCTGLRGLLQFENVSYGIEPLESSVGFEHVIYQVKHKKADVSLYNEKDIESRDLSFKLQSIEPQKDFAKYIEMHVVVEKQLYNHMGSGTTVVTQKIFQLIGLTNAIFVSLNITVILSSLELWIDENKIATTGDAKELLHTFLRWKRSYLVLRPHDVAFLLVYREKSNYVGATFQGKMCDANYAGGVLLHPRTISLESLAVILAQLLSLSMGIPYDDINQCQCSAAVCIMNPEAIHFSGVKIFSNCSIEDFAHFISKQKSQCLHNQPRLDPFFKQQAVCGNAKLEAGEECDCGTQQNCFLLGAKCCDTATCRFKAGSNCAEGPCCENCLFMSQERVCRPSFDECDLPEYCNGTSASCPENHFIQTGHPCGPNQWVCIDGVCMNGDKQCMDTFGGEAEFGPTECYSYLNSKTDVSGNCGIGDSGYTQCEADNLQCGKLICKYAGEFLLQIPRATIIYANISGHLCVAVEFASDHEDSHKMWIKDGTSCGSNKVCKNQRCVSSSYLGYDCTTDKCNHRGVCNNKKHCHCSASYLPPDCSVQSDTSPGGSIDSGNFPLVAVPARLPERRHMENVYHSKPMRWPLFLFIPFFIIFCVLIAIMVKVHFQRKKWRTEDYSTDEQPESESEPKG
What is the function of this protein?
Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization.  Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct.  Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg.  This is a non catalytic metalloprotease-like protein (By similarity).
What are the official names of this protein?
Disintegrin and metalloproteinase domain-containing protein 2, ADAM 2, Fertilin subunit beta, PH-30, PH30, PH30-beta.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: MENE_BACVZ
Sequence: MLTEQPNWLIQRAQLTPERIALIFENKQMTFRELYHASKQMAARLSKYCSLKKGDRAAILLSNRPEMVYAVHACFLLGAEAVLLNTKLSKQERLFQLEDSQAKLLLMEDGFCREEYESAVATADVDELQAEEAGDIEPEAYVTLDDTATLMYTSGTTGRPKGVQQTFGNHYSSAVSSALNLGVTERDRWLIALPLFHISGLSALFKSVIYGMPVVLHQKFSVTDVLDSISSHQVTIISAVQTMLSGLLAETEQCPESLRCILLGGGPAPLPLLEECRRKQFPVFQSYGLTETCSQIVTLSPEFSMDKLGSAGKPLFSCEIRIEKDGNPCAPFEHGEITVKGPNVMKGYYHRDDANQAAFHNGWFKTGDLGYLDDEGFLYVLDRRSDLIISGGENIYPAEVEAALLAHPAVAEAGVSGSEDPKWGKVPHAFLVLTSSVSSEELTAFCRERLAKYKIPAAFFEVDGLPRNASNKLMRHRLNELRKGELS
What is the function of this protein?
Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).
What are the official names of this protein?
2-succinylbenzoate--CoA ligase, o-succinylbenzoyl-CoA synthetase, OSB-CoA synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.