PharMolix/UniProtQA huggingface dataset:
Protein: EFG_META1
Sequence: MAREYKLEDYRNIGIMAHIDAGKTTTTERVLFHTGKIHKIGETHEGESQMDWMVQEQERGITITSAATTAYWGGKRLNIIDTPGHVDFTVEVERSLRVLDGAVAVLDAQSGVEPQTETVWRQATNYNVPRIVYVNKMDKAGANFKASTESLRKLLGANAHPIQLNIGEEAQFTGIIDLVEMKAYEFDGKPEENMKEIPIPAHLLDEATLMRSSLIESVADFDEEIMEALLEEKEVSIEKIKAAIRKATLSATYFPVVCGTSFKNKGVKLMLNAIVDYLPSPLDIPPMKAYKGEGEISIPASDDEFFSSLAFKVMNDPYVGNLTFFRVYSGILNKGTYLYNSTKGEKERIGRILLMHANSRTDIDEVRTGDIGAAVGLKFTTTGDTLIDEKHKDIVLENMNFPEPVISQALEPASKDASEKLSLALQRLAAEDPTFKYYTDEETGQTIIAGMGELHLDIIVDRLKREFKVAANVGAPQVSYRETITKSAEVEGIHKKQSGGKGQYGHVWIKYEPNPDKGFEFVDKIVGGKIPKEYIKSIEKGLKEKMEIGILAGYPLIDVKATLFDGSYHEVDSSELAYKIAASKSLTKGREMLGTVLLEPIMDVAVVIPEDFFGDVMGDISRRRGQVRDNETRNDGAHVIKAYIPLSEMFGYATELRSMTTGRGTYQMWFDHYEKLPRNLADEIIKKRGGKVKIDED
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BH104_ARATH
Sequence: MYPSLDDDFVSDLFCFDQSNGAELDDYTQFGVNLQTDQEDTFPDFVSYGVNLQQEPDEVFSIGASQLDLSSYNGVLSLEPEQVGQQDCEVVQEEEVEINSGSSGGAVKEEQEHLDDDCSRKRARTGSCSRGGGTKACRERLRREKLNERFMDLSSVLEPGRTPKTDKPAILDDAIRILNQLRDEALKLEETNQKLLEEIKSLKAEKNELREEKLVLKADKEKTEQQLKSMTAPSSGFIPHIPAAFNHNKMAVYPSYGYMPMWHYMPQSVRDTSRDQELRPPAA
What are the official names of this protein?
Transcription factor bHLH104, Basic helix-loop-helix protein 104, AtbHLH104, bHLH 104, Transcription factor EN 136, bHLH transcription factor bHLH104.
What are the subcellular locations of this protein?
Nucleus.
Protein: NRAM_I43A0
Sequence: MNPNQKIITIGSICMVVGIISLILQIGNIISIWISHSIQTGSQNHTGTCNQSIITYKNSTWVNQTYVNISNTNVVAGKDTTSVILAGNSSLCPIRGWAIYSKDNGVRIGSKGDVFVIREPFISCSHLECRTFFLTQGALLNDKHSNGTVKDRSPYRALMSCPVGEAPSPYNSRFESVAWSASACHDGMGWLTIGISGPDDGAVAVLKYNGIITETIKSWRKEILRTQESECACVNGSCFTIMTDGPSGGPASYKIFKIEKGKVTKSIELDAPNSHYEECSCYPDTGKVMCVCRDNWHGSNRPWVSFDQNLDYQMGYICSGVFGDNPRPKDGKGNCGPVYVDGANGVKGFSYRYGNGVWIGRTKSNSSRQGFEMIWDPNGWTETDSNFFVKQDVVAVTDWSGYSGSFVQHPELTGLDCMRPCFWVELIRGRPKEKTIWTSGSSISFCGVNSDTVDWSWPDGAELPFTIDK
What is the function of this protein?
Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates.  Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release.  Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell.  Otherwise, infection would be limited to one round of replication.  Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors.  May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells.  Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport.  May additionally display a raft-association independent effect on budding.  Plays a role in the determination of host range restriction on replication and virulence.  Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
What are the official names of this protein?
Neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 34 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type II membrane protein. Note=Preferentially accumulates at the apical plasma membrane in infected polarized epithelial cells, which is the virus assembly site. Uses lipid rafts for cell surface transport and apical sorting. In the virion, forms a mushroom-shaped spike on the surface of the membrane.
Protein: RK27_TRICV
Sequence: MAHKKGAGSTKNGRDSNAKRLGVKRFGGQRVKAGNILVRQRGMKFTPGLNVGCGKDFTLYALTDGIVNFDYKNAQQKRINIIG
What are the official names of this protein?
50S ribosomal protein L27, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GMT1_CRYNJ
Sequence: MSKPFVPTPNISRPATPSSLDYGKDEASSTLLRDMGERGDRERKDREERDKKEAMPSGQDQVLPILSYCAASIMMTVVNKYVVSGANFTMTFLLLAIQSSVCVLAVTTVKKLGFISFRDFDKNDAKAWWPISTLLVAVIYTGSKALQFLSIPVYTIFKNLTIILIAYGEVFMFNGAVSGLTLCSFALMVGSSIIAAWSDITSVWNKEPELDPITGLEITVGPVSTIGGLNAGYIWMALNCFVSAAYVLFMRKRIKVTGFKDWDSMYYNNLLSIPILVVFSLVIEDWGSESLALNFPASNRVLLLSAMAFSGAAAVFISYSTAWCVRITGSTTYSMVGALNKLPVAASGILFFGDPANFGNISAIAVGGVAGVVYAVAKTNQAKVEKARQARAAGGRP
What is the function of this protein?
Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.  Involved in capsule synthesis.
What are the official names of this protein?
GDP-mannose transporter 1, GMT 1.
What is the protein family that this protein belongs to?
Belongs to the TPT transporter family. SLC35D subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SHOC2_RAT
Sequence: MSSSLGKEKDSKEKDPKVPSAKEREKEAKASGGFGKESKEKEPKTKGKDAKDGKKESSAAQPGVAFSVDNTIKRPNPALGTRKKSSNAEVTKELNKCREENSMRLDLSKRSIHILPPSVKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITAVEKDVRNLPRLSTLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLNRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHLPPQIVAGGPSFIIQFLKMQGPYRAMV
What is the function of this protein?
Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation.  Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.
What are the official names of this protein?
Leucine-rich repeat protein SHOC-2, Protein soc-2 homolog, Protein sur-8 homolog.
What is the protein family that this protein belongs to?
Belongs to the SHOC2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates from cytoplasm to nucleus upon growth factor stimulation.
Protein: RECA_MYCLE
Sequence: MAQVPDREKALELAMAQIEKNYGKGSVMRLGDEMCQPISVIPTGSIALDVALGIGGLPRGRIVEIYGPESSGKTTVALHAVANAQAVGGVAAFIDAEHALEPEYAKKLGVDTDSLLVSQPDTGEQALEIADMLIRSGALDIVVIDSVAALVPRAELEGEMGDSYVGLQARLMSQALRKMTGALSNSGTTAIFINQLREKIGVMFGCMNYSTRVTLADGSTEKIGKIVNNKMDVRVLSYDPVTDRIVPRKVVNWFNNGPAEQFLQFTVEKSGSNGKSQFAATPNHLIRTPGGWTEAGNLIAGDRVLAVEPHMLSDQQFQVVLGSLMGDGNLSPNLCDRNGVRFRLLGYGCKQVEYLQWKKALMGNIRHTVRENSMGASFIDFTPLPELVELQRAVYLGDGKKFLSEEYLKALTPLVLAIWYMDDGSFTVGSKRVQERTAGGSGRIEICVDAMTEGTRVRLRDYLCDTHGLDVRLREVGSAGKAVLVFSTAATAKFQSLIAPYVAPSMEYKLLPQFRGRGSVTPQFVEPTQQLVPARVLDVHVKLSTRSMNRFDIEVEGNHNYFVDGVMVHNSPETTTGGKALKFYASVRMDVRRIETLKDGVDAVGNRTRVKIVKNKVSPPFKQAEFDILYGKGISREGSLIDMGVEQGFVRKSGSWFTYEGEQLGQGKENARNFLLENADVANEIEKKIKEKLGIGAVVTDDDILPTPVDF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity).
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCTM1_HUMAN
Sequence: MQTCPLAFPGHVSQALGTLLFLAASLSAQNEGWDSPICTEGVVSVSWGENTVMSCNISNAFSHVNIKLRAHGQESAIFNEVAPGYFSRDGWQLQVQGGVAQLVIKGARDSHAGLYMWHLVGHQRNNRQVTLEVSGAEPQSAPDTGFWPVPAVVTAVFILLVALVMFAWYRCRCSQQRREKKFFLLEPQMKVAALRAGAQQGLSRASAELWTPDSEPTPRPLALVFKPSPLGALELLSPQPLFPYAADP
What is the function of this protein?
May be involved in thymocyte signaling.
What are the official names of this protein?
Secreted and transmembrane protein 1, Protein K-12.
What is the protein family that this protein belongs to?
Belongs to the SECTM family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Secreted.
Protein: UXAB_ECO5E
Sequence: MKTLNRRDFPGAQYPERIIQFGEGNFLRAFVDWQIDLLNEHTDLNSGVVVVRPIETSFPPSLSTQDGLYTTIIRGLNEKGEAVSDARLIRSVNREISVYSEYDEFLKLAHNPEMRFVFSNTTEAGISYHAGDKFDDAPAVSYPAKLTRLLFERFSHFNGALDKGWIIIPCELIDYNGDALRELVLRYAQEWALPEAFIQWLDQANSFCSTLVDRIVTGYPRDEVAKLEEELGYHDGFLDTAEHFYLFVIQGPKSLATELRLDKYPLNVLIVDDIKPYKERKVAILNGAHTALVPVAFQAGLDTVGEAMNDAEICAFVEKAIYEEIIPVLDLPRDELESFASAVTGRFRNPYIKHQLLSIALNGMTKFRTRILPQLLAGQKANGTLPARLTFALAALIAFYRGERNGETYPVQDDAHWLERYQQLWSQHRDRVIGTQELVAIVLAEKDHWEQDLTQVPGLVEQVANDLDAILEKGMREAVRPLC
What are the official names of this protein?
Altronate oxidoreductase, Tagaturonate dehydrogenase, Tagaturonate reductase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family. UxaB subfamily.
Protein: RPOC_MYCCT
Sequence: MENLNRKKAIKIELANPDTIRSWSHGEVLKPETINYKTLKAEKDGLFDERIFGPTKNYECVCGRYKKANPMNKGKKCEKCGVELTESIVRRERMGHIELEEPVTHIWMLKVAPYRIAAILDLKAKELEEVVYFVSHIVLEQGNQSHFLEKEVLDLGSSRITKTREKLQLSILDVIDQINDPEHRDTKKANRLLEELKNTSIPFSIDEATSLISKYTNAKFGIGARAVEYLLEKVDLTKEIEAIKIQLENSKKTPNERTKLLKRLETFDSLKRSKQRPEWMVMRVIPVIPPDIRPIIQLDGGRFTTSEINDLYRRIIIRNERLKKVKEMGAPSIIVNNEKRMLQEAVDALFDNERKPKPVQGKNKRPLKSLTSVLKGKQGRFRQNLLGKRVDYSARSVIAIGPDLKMYQAGLPREMAITLFKPFVIQWLQDHEYAENVKIAEKMLLQNDPKVWEALEQVIKDRPVLLNRAPTLHRLGIQAFEPKLVKGKAIRLHPLVTTAFNADFDGDQMAVHVPITKEAVAESRALMLGSSAILGPKDGKAIVTPGQDIILGNYYLTTEEKNAKGQGMIFSSLDEAFMAYNSGQIHLNSLIGIALSALPEEKFSDKNQRLNSYLLTTVGKLYFNQIFDDNFPWINSNNIWNAKEAVKEFIYDFSQDIDKVIENVQVQQPIKKKELSLIIERYFETHGARKTAEMLDKMKDLGFSFSTKSGTTISAGDVVAFTHKYDEFKEADQKVEQITDFYNMGMLTNSEKKRRIIDVWSEVKDKIQNELATVLRKDVKNPIFVMVDSGARGNVSNFTQLVGMRGLMNDTKGDIKEIPIKSSFREGLTVSEYFVSTHGARKGMADIALKTADSGYLTRRLVDVSQEIVVVNEDCEPTKGFEVSAIIDTKHDNVIVPLKDRLVGRFTFEDIYDDDKNLVASANTLIDKNIAEKIIMSGISSVIIRSVLTCDNKRGVCQKCYGLNLATASVVNIGEPVGVIAAQSIGEPGTQLTMRNFHTGGVAGNVDITQGLPRIKELLDVTTPKGAVAIISEVDGVVSEIEDYNGVFVINIVTENEEVKKYKTEFNSVLRVEQGSSVMAGQKLTEGAIDLHQLLEFGGIQDVQNYILKEVQKVYRLQGIEISDKYIEIIIKQMLNKVKITDSGDSDLLPGEIITIQNYKEVVQDCIVKSIRPPLSKAQIFGIKKAPLESSSWLSSASFQDTARVLTRAIIKGKEDKLEGLKENIMLGNLIPAGTGLTGTQEVEQLAEQYHNNEY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: OVCA2_MOUSE
Sequence: MAARQTLRVLCLAGFRQSERGFREKTGALRKTLRGRAELVCLSGPHPVPEAAAPEGSCPDSGPCSPEEQPRGWWFSEEEADVFSALEESTVCRGLQEALETVARALDTLGPFDGLLGFSQGAALAAYVCALGQAGDPRFPLPRFIILVSGFCPRGLKEPILQSPMSLPSLHVFGDTDRVIPSQESMQLASRFLGAVTLTHSGGHFIPAAASQRQAYLKFLDQFAE
What are the official names of this protein?
Esterase OVCA2, Ovarian cancer-associated gene 2 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the LovG family.
Protein: H12A3_CYRHA
Sequence: MLIKQFSRRSKNTKVQILLAFAALFVLAVGSYASESKKLDLRDALFSAMFSADYQLNPQERGCRYFLGECKKTSECCEHLACHDKHKWCAWDWTIGK
What is the function of this protein?
Ion channel inhibitor.
What are the official names of this protein?
U6-theraphotoxin-Hhn1a 3, U6-TRTX-Hhn1a, Hainantoxin-XII.3, HNTX-XII.3.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 12 (Hntx-12) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HEMA_I01A1
Sequence: SLVKSDQICIGYHANNSTEQVDTIMEKNVTVTHAQDILEKTHNGKLCDLDGVKPLILRDCSVAGWLLGNPMCDEFINVPEWSYIVEKASPANDLCYPGDFNDYEELKHLLSRINHFEKIQIIPKSSWSNHEASSGVSSACPYLGKSSFFRNVVWLIKKNSAYPTIKRSYNNTNQEDLLVLWGIHHPNDAAEQTKLYQNPTTYISVGTSTLNQRLVPKIATRSKVNGQSGRMEFFWTILKPNDAINFESNGNFIAPEYAYKIVKKGDSAIMKSELEYGNCNTKCQTPMGAINSSMPFHNIHPLTIGECPKYVKSNRLVLATGLRNTPQRERRRKKRGLFGAIAGFIEGGWQGMVDGWYGYHHSNEQGSGYAADKESTQKAIDGVTNKVNSIIDKMNTQFEAVGREFNNLERRIENLNKKMEDGFLDVWTYNAELLVLMENERTLDFHDSNVKNLYDKVRLQLRDNAKELGNGCFEFYHKCDNECMESVKNGTYDYPQYSEEARLNREEISGVKLESMGTYQILSIYSTVASSLTLAIMVAGLSLWMCSNGSLQ
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: CXCR4_PANTR
Sequence: MEGISIYTSDNYTEEMGSGDYDSMKEPCFREENANFNKIFLPTIYSIIFLTGIVGNGLVILVMGYQKKLRSMTDKYRLHLSVADLLFVITLPFWAVDAVANWYFGNFLCKAVHVIYTVNLYSSVLILAFISLDRYLAIVHATNSQRPRKLLAEKVVYVGVWIPALLLTIPDFIFANVSEADDRYICDRFYPNDLWVVVFQFQHIMVGLILPGIVILSCYCIIISKLSHSKGHQKRKALKTTVILILAFFACWLPYYIGISIDSFILLEIIKQGCEFENTVHKWISITEALAFFHCCLNPILYAFLGAKFKTSAQHALTSVSRGSSLKILSKGKRGGHSSVSTESESSSFHSS
What is the function of this protein?
Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation.  Involved in the AKT signaling cascade (By similarity).  Plays a role in regulation of cell migration, e. g.  during wound healing.  Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels.  Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes (By similarity).  Involved in hematopoiesis and in cardiac ventricular septum formation.  Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells.  Involved in cerebellar development.  In the CNS, could mediate hippocampal-neuron survival (By similarity).
What are the official names of this protein?
C-X-C chemokine receptor type 4, CXC-R4, CXCR-4, Fusin, Stromal cell-derived factor 1 receptor, SDF-1 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction. Early endosome. Late endosome. Lysosome. Note=In unstimulated cells, diffuse pattern on plasma membrane. On agonist stimulation, colocalizes with ITCH at the plasma membrane where it becomes ubiquitinated (By similarity). In the presence of antigen, distributes to the immunological synapse forming at the T-cell-APC contact area, where it localizes at the peripheral and distal supramolecular activation cluster (SMAC) (By similarity).
Protein: HINT1_ARATH
Sequence: MSHRVSILSSHFSPASAVMASEKEAALAATPSDSPTIFDKIISKEIPSTVVFEDDKVLAFRDITPQGPVHILLIPKVRDGLTGLSKAEERHIDILGRLLYTAKLVAKQEGLAEGFRIVINDGPQGCQSVYHIHVHLIGGRQMNWPPG
What is the function of this protein?
Possesses adenylylsulfatase activity in vitro.
What are the official names of this protein?
Adenylylsulfatase HINT1, HIS triad family protein 3, Histidine triad nucleotide-binding protein 1.
What are the subcellular locations of this protein?
Peroxisome. Plastid, chloroplast.
Protein: GNAO_LOCMI
Sequence: MGCAMSAEERAALARSKQIEKNLKEDGLQAAKDIKLLLLGAGESGKSTIVKQMKIIHESGFTAEDFKQYRPVVYSNTIQSLVAILRAMPNLGISFCNNERETDAKMVFDVIQRMEDTEPFSEELLAAMKRLWADSGVQECFGRSNEYQLNDSAKYFLDDLDRLGAKDYQPTEQDILRTRVKTTGIVEVHFSFKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICFPEYAGAQEYGEAAAYIQAQFEAKNKSTTKEIYCHMTCATDTNNIQFVFDAVTDVIIANNLRGCGLY
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.  The G(o) protein function is not clear.
What are the official names of this protein?
Guanine nucleotide-binding protein G(o) subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family. G(i/o/t/z) subfamily.
Protein: PROA_PROMH
Sequence: MLEQMGKAAREASWHLAQLSTEQKNQALLVIADLLEQQEAIILAANEKDMVAARESNINAAMLDRLLLTSERLKAIADDVRQVCHLEDPVGQVIDGRLLDSGLRLERRRVPLGVVGVIYEARPNVTIDVASLCLKTGNAAILRGGKETHHTNQAVVAVIQQALETCAIPAAAIQAIDKPDRELVAKMLKMDEYIDMLIPRGGAGLHKLCREQSTIPVITGGIGVCHTFVDESADLDQALNVIINAKVQRPSACNSLETLLVHEAIAESFLPQLSDAMAAQKVTLHASQRAITALKKGRATVVDVTEADYCDEWLSLDLNVEVVNDLTAAIAHIRQYGTAHSDAILTQSISHADRFVRQVDSAAVYVNASTRFTDGGQFGLGAEVAVSTQKLHARGPMGLDALTTYKWIGYGDNTLRR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYC6_ARATH
Sequence: MDRIAQSDLSLGFGSSHALPLPHPPRIPIADDSITLQIDSSFRPSSNPMPPVPLQLLEQRFDVTGSCSRVVEEDDEVVGDNDDDDQREEEQFILLGHPMKLKRGRGGNSYSLASSSPCKRFVVDSGIESRRAVVRAWGNQSIEEADPEIHEFMEKEKQRQFRGIELIASENFVCRAVMEALGSHLTNKYSEGMPGARYYTGNQYIDQIEILCQERALAAFGLNHEKWGVNVQPYSCTSANFAVFTGLLMPGERIMGLDSPSGGHMSHGYYTPGGKKVSGASIFFESFPYKVDPRTGYIDYDKLEEKALDYRPKILICGGSSYPRDWEFPRFRHIADKCGAVLMFDMAQISGLVAAKESPNPFDYCDIVTSTTHKSLRGPRGGIIFYKRGLKPKKQSINLNHCESNIQYDFEEKINFSVFPSLQGGPHNNHIAALAIALKQAASPEYKLYMRQVKKNAKALASALISRKCKLITGGTDNHLLLWDLTPLGLTGKVYEKVCEMCHITVNKVAIFSENGVISPGGVRIGSPAMTSRGCLEPEFETMADFLYRAAQIASAAQREHGKLQKEPLKSIYHCKEIADLRNQVEAFATQFAMPAFDM
What is the function of this protein?
Catalyzes the interconversion of serine and glycine.
What are the official names of this protein?
Serine hydroxymethyltransferase 6, AtSHMT6, Glycine hydroxymethyltransferase 6, Serine methylase 6.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBED_SALTI
Sequence: MKTKLNELLEFPTPFTYKVMGQALPELVDQVVEVVQRHAPGDYSPTVKPSSKGNYHSVSITINATHIEQVETLYEELGNIDIVRMVL
What are the official names of this protein?
UPF0250 protein YbeD.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.
Protein: ACBC_ACTS5
Sequence: MSGVETVGVHADAHRDSWQVRAQKQITYEVRFRDDVFGLDSTDLLEAGADGAGSRRRFVVVDSAVDALYGSRIREYFTHHGIDHSILVMRVGETVKDFDTAGRIVAAMDAFGLARRREPMIVVGGGVLMDVAGLVASLYRRGTPFLRVPTTLVGLIDAGVGAKTGVNFNGHKNRLGTYAPADLTLLDRRFLATLDRRHLSNGLAEMLKIALIKDAELFQLLERHGRVLIEERFQGRTGTGDRAAVRALRAATHGMLEELGPNLWESRLERSVDYGHTFSPTIEMRALPALLHGEAVCVDMALTTVLAYRRGLLDVAQRDRIFAVMTALGLPTWHPLLTPEVLEAALQDTVRHRDGWQRLPLPVGIGGVTFVNDVTAAELQAAALMQHRLAEDALLLRA
What is the function of this protein?
Catalyzes the cyclization of D-sedoheptulose 7-phosphate to 2-epi-5-epi-valiolone.  Does not use ido-heptulose 7-phosphate and 3-deoxy-arabino-heptulosonate 7-phosphate.  Involved in the biosynthesis of the acarviose moiety of the alpha-glucosidase inhibitor acarbose.
What are the official names of this protein?
2-epi-5-epi-valiolone synthase, EEVS, C7-cyclitol synthase, Sedoheptulose 7-phosphate cyclase.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. EEVS family.
Protein: CAPP_STRMU
Sequence: MTINKLESRNDKEAIAEEITILTKLLDDATKTMVGSASFDKITLFKKLSIEEKHQELEREIEQLTNEEMVVVSRYFSILPLLINISEDVNLAYEINYQNNNDIDYLGKLSATIELVSSQKNAQEILENVNVVPVLTAHPTQVQRKTMLDLTNHIHELLRKYRDVKAGSINKQKWYDDMRRYVELIMQTDIIREKKLKVTNEITNVMEYYNSSLIKGVTKLITEYKHLSHQKGFDLGNAKPITMGMWIGGDRDGNPFVTAETLKISALVQNEVILNYYIDKVSDLYRTFSLSTSLSTISNAVKEMADRSTDVSIYREKEPYRKAFHYIQSRLQETLIYLKNNHLEELESEDSAQILPYQSAQEFRNDLQLIKDSLLENNGSAFITGDLTELLQAVDVFGFFLASIDMRQDSSVHETCVAELLASANIVANYSDLPEEEKIAILLKELTEDPRILSATHVEKSEILQKELAIFKTARKLKDALGEDVIKQHIISHTESISDMFELAIMLKEVGLVDTDKARVQIVPLFETIEDLDNSREIMRQYLNYDIVKKWIAANHNYQEIMLGYSDSNKDGGYLSSGWALYKAQNELTEIGYDNGVKITFFHGRGGTVGRGGGPSYEAITSQPFGSIKDRIRLTEQGEVIGNKYGNKDVAYYNLEMLVSATLDRMVTRRIVNSDNLVNYRLIMDEIVADSNLIYRDLVFGNEHFYDYFFAASPIREVSSLNIGSRPAARKTITEISGLRAIPWVFSWSQNRIMFPGWYGVGSAFKHFIDKDEKNLTKLQEMYQSWPFFHSLLSNVDMVLSKSNMNIAFEYAKLCQDEETKEVFATILDEWQLTKNVILAIESHKQLLEDNSYLKASLDYRLPYFNVLNYIQIELIKRQRRGELGENLENLIHITINGVATGLRNSG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: QUEA_JANSC
Sequence: MKLDDFDFDLPDGLIATRPARPRSSARLLVADGPETHDLTVADLPSMLRRGDRLVLNDTRVIPARLTGTRTRMSAQGEVTARIEVTLMEPQADGTWSALAKPMRKLKAGEKIIFSNALQADVHAMDEGLRLAFNVEGDDFDAALNAAGAMPLPPYIAGKRAPDARDYHDYQTIWAKRAGAVAAPTASLHFDEHLMDALTSRGVDVTFVTLHVGAGTFLPVTVDDVTTHKMHAEWGEVRATAAAEINATKAAGGRIIPVGTTALRLIESAAQDGTIHPFEGTTDIFIYPGYRWQITDALMTNFHLPKSTLLMLVSALMGKDRMDAVYAHAIANQYRFFSYGDASLLFPSQKGQTSR
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y780_CAUSK
Sequence: MAGHSKFKNIMHRKGRADAARSKLFSKLSREITVAAKSGVPDPNMNPRLRLAVNNAKAESLPKDVIDRAIKKSQMGDAADYSEIRYEGVAAGGVGIIVEVLTDNKNRAAANVRSYFTKMGGNMGATNSVAFNYDRVGQVSYPAKAASEDDMMEAAIEAGADDVVSDMDEEGEGHIVYTAFESLNEVAAALEAKFGPASNTKIAWRPKMQVPVTGDAVATLMKLLDALNDDDDVQAVYSNEEISDEDVAKLG
What are the official names of this protein?
Probable transcriptional regulatory protein Caul_0780.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.