PharMolix/UniProtQA huggingface dataset:
Protein: ACPS_BURP0
Sequence: MAIYGIGTDLAQVSRIAAVLERTGGRFAEKVLGPDELRVFHARRARSEARGIAFLATRFSAKEAFSKAIGLGMHWPMTWRALQTLNRPSGEPYVVASGELAAWLDARGITARVTVSDERDYAVTFVVAEAPDHVAAARSGAAS
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLO2_BARQU
Sequence: MLIEQFICREDNFGVLIHDERSGYTAAIDAPESKAICSALKRRNWTLQTIFVTHHHHDHIEALAELKQIYKAVVIGPEAEKEKIGHLDQALQPDESLFFGTHTLLALSTPGHTLGSLSYYFPQENLLFSGDTLFSLGCGRLFEGTPAQMLNSFKKLRQLPDETLLYCGHEYTKTNALFALTLDSHNQKLHQRVEDVFLLRAKNAMTLPVTLGQEKATNPFLRWDDRTLRKNLAMEKETDEEVFAEIRKRKDNF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: DHSD_ECO57
Sequence: MVSNASALGRNGVHDFILVRATAIVLTLYIIYMVGFFATSGELTYEVWIGFCASAFTKVFTLLALFSILIHAWIGMWQVLTDYVKPLALRLMLQLVIVVALVVYVIYGFVVVWGV
What is the function of this protein?
Membrane-anchoring subunit of succinate dehydrogenase (SDH).
What are the official names of this protein?
Succinate dehydrogenase hydrophobic membrane anchor subunit.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS4_METBF
Sequence: MAYPGKKSKSFETPRHPWQEARMASEVQLVKAYGLRNKREVWKAASTLRMYRSEARRLLASAANSQERGLEGHQKTQSEEILAKLIRYGIIKSDADIDDILSLKTENILERRLQTQVLRLGLARTVVQARQFITHGHIAINGRKATVPGMLVSKEDEMHIGYYATSPLVSESHPERPVQVASVLADSTTTLRAVAEAKQAKEKPPERGGRKRRGRR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: SIM1_YEAST
Sequence: MKFSTAVTTLISSGAIVSALPHVDVHQEDAHQHKRAVAYKYVYETVVVDSDGHTVTPAASEVATAATSAIITTSVLAPTSSAAAADSSASIAVSSAALAKNEKISDAAASATASTSQGASSSSSSSSATSTLESSSVSSSSEEAAPTSTVVSTSSATQSSASSATKSSTSSTSPSTSTSTSTSSTSSSSSSSSSSSSSSSGSGSIYGDLADFSGPSEKFQDGTIPCDKFPSGQGVISIDWIGEGGWSGVENTDTSTGGSCKEGSYCSYSCQPGMSKTQWPSDQPSDGRSVGGLLCKNGYLYRSNTDADYLCEWGVEAAYVVSKLSKGVAICRTDYPGTENMVIPTYVEGGSSLPLTVVDQDTYFTWEGKKTSAQYYVNNAGVSVEDGCIWGTSGSGIGNWAPLNFGAGSTGGVTYLSLIPNPNNSDALNYNVKIVAADDSSNVIGECVYENGEFSGGADGCTVSVTSGKAHFVLYN
What is the function of this protein?
Involved in the remodeling of the cell wall during the various phases of yeast culture development and under various environmental conditions.  Required for the maintenance of the CLB5 kinase activity.
What are the official names of this protein?
Probable secreted beta-glucosidase SIM1.
What is the protein family that this protein belongs to?
Belongs to the SUN family.
What are the subcellular locations of this protein?
Secreted, cell wall. Note=Non-covalently bound to the cell wall.
Protein: RL21_HELP2
Sequence: MSYAIFKHGGKQYKVVEGDIVLLDKMNKEPKALVELVEVLAVSKEGKLSFGKPFVNGAKIEAEVINEGRGKKVITFKKRRRKDSKTKRGFRRDFTRVRITKIVA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: YL412_YEAST
Sequence: MHLCQNGHYYKPHRASAEKVPYLKKKKKNSRNEGKAKKKNEKKKIGTVEFFQQKKKEKKRVLNAVCGL
What are the official names of this protein?
Uncharacterized protein YLR412C-A.
Protein: EIF3C_ASPCL
Sequence: MSRFFYGGGSDSESSSSDEEELYERDEEEQSEEEESSEEEETSEEGSDDEEGGVTGAARFMRDMSESEESEDEEKTTVVKSAKDKRLEELESTMKLIDNAKKINDWAVISTEFDKLNRQIVKITQAGPTPRVYIKGVADLEDFVNETVSKQKSGDKKLNASNAKGFNAVKQRIKKNNKDYANLIDKYRKNKEAFLEGKDEAAAPAAAAPRVAKLERVEAPVDVPVADDEGFATVGRGGKTLQYTPESILKHLRVIVESRGKKNTDRLEQIRTMEKLLEVAQNPYQRIRVYLTLISTRFDLTSTSSANYMAPEMWKSAEQDFSSLLSVLENNRDYVVTEGVDEWEDDEKQPQVAAGETLYIPGSVVSYAERLDDELTRSLQHIDPHTAEYIERLSDEKQLYTSLVRAQAYVEGLSKAEKSDPKQDSVNRVVMRRLEHVYFKPSQVITILEDATWKALPSELDSGVTPRGKTGDVENLVLTLCNYLFQYSDGIIRARAMLCQIYFLALHDQYYRARDLMLMSHLTENISNFDVSTQILFNRTLVQIGLCAFRAGLIYEAQNTLSEVCGSGRQKELLAQGIILQRYSTVSPEQERLERQRQLPFHMHINLELLECIYLTSSMFLEVPLMAQTSSSPELKRRVISKTFRRMLDYNERQVFTGPAENTRDGVIMSAKFLAAGDWKKAAEMLNSIKIWELMPQPEKIKEMLSQQIQEEGLRTYLFTYAPFYDSVSVATLASMFELSEKKISAIISRMISHEELAAALDQVNGAIVFRKGVELSRLQSQIVTLADKSMALLEGNEKTLEQRTQGMANAFQRDQGAGARGGRGGGRGGHARGGARFPGQQGRRPGGQQFGGGALGGAIKA
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit C, eIF3c, Eukaryotic translation initiation factor 3 93 kDa subunit homolog, eIF3 p93, Translation initiation factor eIF3, p93 subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPH_YERP3
Sequence: MQILLANPRGFCAGVDRAISIVERAIEMYGAPIYVRHEVVHNRYVVESLCERGAIFIEEISEVPDGSILIFSAHGVSQAVRAEARSRNLTMLFDATCPLVTKVHMEVARASRKGKEAILIGHAGHPEVEGTMGQYSNPNGGMYLVESPDDVWQLSVKDENNLCFMTQTTLSVDDTSAVIDALNTRFPKIVGPRKDDICYATTNRQEAVRNLANDADIVLVVGSKNSSNSNRLAELVQRMGKPAYLIDSAADIQEFWLQGAKCIGVTAGASAPDILVQQVIARLKDLGAGESIELSGREENIVFEVPKELRVEVKQID
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: HPPA_RHIRD
Sequence: AGGIAEMAELGPEVRKTTDKLDSVGNTTAAIAKGFAIGSAALTALALFTAFAEEIAKNPKLTGLLVDGHLVVNLTEPGVIIGIFLGATLPFLVCAFTMEAVGKAAFEMIEEVRRQFREIPGIMEGTGRPDYAKCVDISTKAAIREMMLPGVFAVGAPLIVGFLLGAKALAGFLAGVTASGVLLAIFSPS
What is the function of this protein?
Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.
What are the official names of this protein?
Putative K(+)-stimulated pyrophosphate-energized sodium pump, Membrane-bound sodium-translocating pyrophosphatase, Pyrophosphate-energized inorganic pyrophosphatase, Na(+)-PPase.
What is the protein family that this protein belongs to?
Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YDJY_ECOLI
Sequence: MLQHYSVSWKKGLAALCLLAVAGLSGCDQQENAAAKVEYDGLSNSQPLRVDANNHTVTMLVQINGRFLTDDTRHGIVFKDGSNGHKSLFMGYATPKAFYEALKEAGGTPGENMTMDNKETTHVTGSKLDISVNWQGAAKAYSFDEVIVDSNGKKLDMRFGGNLTAAEEKKTGCLVCLDSCPVGIVSNATYTYGAVEKRGEVKFKGNASVLPADNTLATVTFKIAE
What are the official names of this protein?
Uncharacterized protein YdjY.
Protein: RNPH_TROW8
Sequence: MLFCCIICSVLRKNSRAHDEIRPVKIIRGWNIYAEGSALIAFGNTRVLCNATFQRGVPPFLRGQRSGWITAEYAMLPRSGTERSDRESVKGKISGRSHEISRLIGRSMRAILDRYALEENTIILDCDVLQADGGTRTAAITGSYIALYDALVWAKNQKILSKHPLTDSVSAVSVGLVGDQIFLDLDYSEDSNAQADINLVFTGSGKLVEIQGTAEKSPFSYGQFEQMMELAKTGCQALKEIQAASLD
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: FLIP_BUCBP
Sequence: MLIDIMFEKIGISLFELVTSIIFISWIVKKFILDKNVIIQSYMKVESKISLGYNEKIIIVDIKDVRLVLGVTSKRIVHLYTLPPIVYKKSQDSLIKSSNVGYKRNNYIRTMWNKTMVYQIASLCVFLLFCPSYAYAGIPDVISHTSSDGGQIWSIPIQTLVFITSLTFIPTVLLMMTSFSRIVIVFSLLRSALGTPYSPPNQILVGLSLILTFFIMAPIFDKIYQDSYLPFSEDKISIDTAIVRGAKPLHKFMVNQTRQVDLEFFSKLANISTFSRKEEIPMRVLLPSFITSELKTAFQIGFTIFIPFLIIDLVVSSVLMSLGMMMVPPSTISLPFKLMLFVLVDGWQLLITSLTHSFYH
What is the function of this protein?
Plays a role in the flagellum-specific transport system.
What are the official names of this protein?
Flagellar biosynthetic protein FliP.
What is the protein family that this protein belongs to?
Belongs to the FliP/MopC/SpaP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Bacterial flagellum basal body.
Protein: MTNA_ROSS1
Sequence: MSSAFRTVWWEAGQVCLIDQRLLPNETRIVRCAAVEDVAYAIRTMQIRGAPAIGCAAAYGMALAACSAAHDAVGDVARIYARLAEAKALLDAQRPTAVNLSWATRRVLERAQSLNDPSPHDVAQRVLEEAHAILAEDLAMCHAIGRHGVALIPPRGHVLTHCNAGGLATAGYGTALAPVRTAHEQGRPIHVYVDETRPFLQGARLTAWELIQERIPLTLITDNMAGYFMKRGDIDCVIVGADRIVANGDVANKIGTYSLAVLARAHRIPFYVAAPSSTIDCSLPNGDAIPIEERSSDEVTMLFGRRIAPEGVIAAHPAFDVTPADLVTAIITECGVIYPPFAGALQRSGPKRH
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: AROK_LACLA
Sequence: MSIILIGFMGAGKSTVAKLLTENFTDLDQLIEEEIEMTIAEFFELFGEADFRKIENEVFELALQKNIIIATGGGIIENPKNLEALDREAGVVFLTADFETLWERISMDLQNVRPLAQDKKAAQLLFEKRKNDYAKVADLTIDVTDKSPEQIVEEIREKWGIN
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRM56_IGNH4
Sequence: MKVYVLRIGHRPDRDKRITTHVGLVARAFGAHGFVLSPCDEKVLEKLRDVEERWGRLLEEIACTNSPLKYVKTWDGTVVHLTMYGLPVDSVIDEIRQKDKILVIVGAEKVPREYYELAHYNVAIGNQPHSEVAALAIFLDRLYGGAELYRQPVGGKLRIIPTEKGKKVVKVGEEGPSGGAPGVRAERGRGGRGEGVQGADEVRGHKRGATDRDLGDET
What is the function of this protein?
Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.
What are the official names of this protein?
tRNA (cytidine(56)-2'-O)-methyltransferase, tRNA ribose 2'-O-methyltransferase aTrm56.
What is the protein family that this protein belongs to?
Belongs to the aTrm56 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C3H_NARPS
Sequence: MDPSPLSISIAIFSLLISFLLYKKLTTKLPPGPKPWPVVGNLYDIKPVRFRCFAEWAQTYGPIMSVWFGTTLNIVVSSSELAKEVLKEKDQILADRPRNRAAARFSRDGKDLIWADYGPHYVKVRKVCNLELFSPKRLEGLRPIREDEVTAMVESIFRECTQQDKIGNSLVVRNHLSGVAFSNITRLAFGKRFVNSEGVMDEQGLEFKAIVANGLKLGASLSLGEYVTWLKWMFPFDEEAVAKHGARRDRLTRAIMEEHSLARKESGARQHFVDALLTLQEKYDLSEDTIIGLLWDMITAGMDTTVISVEWAMAELVKHPRVQEKVQEELDRVIGVDRIMTESDFPNLPYLHCVVKEALRLHPPTPLMLPHKASANTKIGGYDIPKGAVVHVNVWAIARDPNSWKNPLEFRPERFQEESIDIKGNDFRVLPFGAGRRVCPGAQLGINLVQSMLGHLLHHFKWELPEGMKPEEIDMTENPGMVTFMHTPLQAVAIPRLPSHLYKRMAVDM
What is the function of this protein?
Cytochrome P450 which catalyzes 3'-hydroxylation of p-coumaric esters of shikimic/quinic acids to form lignin monomers and caffeic acid (By similarity).  Involved in the biosynthesis of phenylpropanoids and Amaryllidaceae alkaloids, including haemanthamine- and crinamine-type alkaloids, promising anticancer agents (PubMed:29229969).
What are the official names of this protein?
p-coumarate 3-hydroxylase, Cytochrome P450 C3H.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ENTS_ECO7I
Sequence: MNKQSWLLNLSLLKTHPAFRAVFLARFISIVSLGLLGVAVPVQIQMMTHSTWQVGLSVTLTGGAMFVGLMVGGVLADRYERKKVILLARGTCGIGFIGLCLNALLPEPSLLAIYLLGLWDGFFASLGVTALLAATPALVGRENLMQAGAITMLTVRLGSVISPMIGGLLLATGGVAWNYGLAAAGTFITLLPLLSLPALPPPPQPREHPLKSLLAGFRFLLASPLVGGIALLGGLLTMASAVRVLYPALADNWQMSAAQIGFLYAAIPLGAAIGALTSGKLAHSARPGLLMLLSTLGSFLAIGLFGLMPMWILGVVCLALFGWLSAVSSLLQYTMLQTQTPEAMLGRINGLWTAQNVTGDAIGAALLGGLGAMMTPVASASASGFGLLIIGVLLLLVLVELRRFRQTPPQMTASDS
What is the function of this protein?
Component of an export pathway for enterobactin.
What are the official names of this protein?
Enterobactin exporter EntS.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. EntS (TC 2.A.1.38) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: U239_DROER
Sequence: MSASADSLAAAASLDKYGDEDIFSLLIRYGLYVGALFQFVCISAAVLMENNPDVNSNPETGEVTEREGEPVRTRLHKIRKLEKKKRR
What are the official names of this protein?
Protein anon-73B1.
What is the protein family that this protein belongs to?
Belongs to the UPF0239 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ASGR2_MOUSE
Sequence: MEKDCQDIQQLDSEENDHQLSGDDEHGSHVQDPRIENPHWKGQPLSRPFPQRLCSTFRLSLLALAFNILLLVVICVVSSQSIQLQEEFRTLKETFSNFSSSTLMEFGALDTLGGSTNAILTSWLAQLEEKQQQLKADHSTLLFHLKHFPMDLRTLTCQLAYFQSNGTECCPVNWVEFGGSCYWFSRDGLTWAEADQYCQLENAHLLVINSREEQDFVVKHRSQFHIWIGLTDRDGSWKWVDGTDYRSNYRNWAFTQPDNWQGHEQGGGEDCAEILSDGHWNDNFCQQVNRWVCEKRRNITH
What is the function of this protein?
Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed.  The receptor recognizes terminal galactose and N-acetylgalactosamine units.  After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated.  The receptor then returns to the cell membrane surface.
What are the official names of this protein?
Asialoglycoprotein receptor 2, ASGP-R 2, ASGPR 2, Hepatic lectin 2, HL-2, mHL-2.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: PEPL_HUMAN
Sequence: MNSLFRKRNKGKYSPTVQTRSISNKELSELIEQLQKNADQVEKNIVDTEAKMQSDLARLQEGRQPEHRDVTLQKVLDSEKLLYVLEADAAIAKHMKHPQGDMIAEDIRQLKERVTNLRGKHKQIYRLAVKEVDPQVNWAALVEEKLDKLNNQSFGTDLPLVDHQVEEHNIFHNEVKAIGPHLAKDGDKEQNSELRAKYQKLLAASQARQQHLSSLQDYMQRCTNELYWLDQQAKGRMQYDWSDRNLDYPSRRRQYENFINRNLEAKEERINKLHSEGDQLLAAEHPGRNSIEAHMEAVHADWKEYLNLLICEESHLKYMEDYHQFHEDVKDAQELLRKVDSDLNQKYGPDFKDRYQIELLLRELDDQEKVLDKYEDVVQGLQKRGQQVVPLKYRRETPLKPIPVEALCDFEGEQGLISRGYSYTLQKNNGESWELMDSAGNKLIAPAVCFVIPPTDPEALALADSLGSQYRSVRQKAAGSKRTLQQRYEVLKTENPGDASDLQGRQLLAGLDKVASDLDRQEKAITGILRPPLEQGRAVQDSAERAKDLKNITNELLRIEPEKTRSTAEGEAFIQALPGSGTTPLLRTRVEDTNRKYEHLLQLLDLAQEKVDVANRLEKSLQQSWELLATHENHLNQDDTVPESSRVLDSKGQELAAMACELQAQKSLLGEVEQNLQAAKQCSSTLASRFQEHCPDLERQEAEVHKLGQRFNNLRQQVERRAQSLQSAKAAYEHFHRGHDHVLQFLVSIPSYEPQETDSLSQMETKLKNQKNLLDEIASREQEVQKICANSQQYQQAVKDYELEAEKLRSLLDLENGRRSHVSKRARLQSPATKVKEEEAALAAKFTEVYAINRQRLQNLEFALNLLRQQPEVEVTHETLQRNRPDSGVEEAWKIRKELDEETERRRQLENEVKSTQEEIWTLRNQGPQESVVRKEVLKKVPDPVLEESFQQLQRTLAEEQHKNQLLQEELEALQLQLRALEQETRDGGQEYVVKEVLRIEPDRAQADEVLQLREELEALRRQKGAREAEVLLLQQRVAALAEEKSRAQEKVTEKEVVKLQNDPQLEAEYQQLQEDHQRQDQLREKQEEELSFLQDKLKRLEKERAMAEGKITVKEVLKVEKDAATEREVSDLTRQYEDEAAKARASQREKTELLRKIWALEEENAKVVVQEKVREIVRPDPKAESEVANLRLELVEQERKYRGAEEQLRSYQSELEALRRRGPQVEVKEVTKEVIKYKTDPEMEKELQRLREEIVDKTRLIERCDLEIYQLKKEIQALKDTKPQVQTKEVVQEILQFQEDPQTKEEVASLRAKLSEEQKKQVDLERERASQEEQIARKEEELSRVKERVVQQEVVRYEEEPGLRAEASAFAESIDVELRQIDKLRAELRRLQRRRTELERQLEELERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQDPQQAREHALLRLQLEEEQHRRQLLEGELETLRRKLAALEKAEVKEKVVLSESVQVEKGDTEQEIQRLKSSLEEESRSKRELDVEVSRLEARLSELEFHNSKSSKELDFLREENHKLQLERQNLQLETRRLQSEINMAATETRDLRNMTVADSGTNHDSRLWSLERELDDLKRLSKDKDLEIDELQKRLGSVAVKREQRENHLRRSIVVIHPDTGRELSPEEAHRAGLIDWNMFVKLRSQECDWEEISVKGPNGESSVIHDRKSGKKFSIEEALQSGRLTPAQYDRYVNKDMSIQELAVLVSGQK
What is the function of this protein?
Component of the cornified envelope of keratinocytes.  May link the cornified envelope to desmosomes and intermediate filaments.  May act as a localization signal in PKB/AKT-mediated signaling.
What are the official names of this protein?
Periplakin, 190 kDa paraneoplastic pemphigus antigen, 195 kDa cornified envelope precursor protein.
What is the protein family that this protein belongs to?
Belongs to the plakin or cytolinker family.
What are the subcellular locations of this protein?
Cell junction, desmosome. Cytoplasm, cytoskeleton. Cell membrane. Cytoplasm.
Protein: RL30_LACDA
Sequence: MTDLKITLIRSVAHRLPEQRKVVKALGLGKINSTVVQPDNAATRGALMKIAHLISVEEVNK
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: SECB_SALPA
Sequence: MSEQNNTEMAFQIQRIYTKDVSFEAPNAPHVFQKDWQPEVKLDLDTASSQLADDVYEVVLRVTVTASLGEETAFLCEVQQAGIFSISGIEGTQMAHCLGAYCPNILFPYARECITSLVSRGTFPQLNLAPVNFDALFMNYLQQQAGEGTEEHQDA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YPR08_YEAST
Sequence: MKSLHDSLSVTDIKRSRLQISMQTLCPFLEDTLQCKSLLSLVVERCTCNAKVVSSILTGGKIFSLKLTLI
What are the official names of this protein?
Uncharacterized protein YPR108W-A.
Protein: HFAA_CAUVC
Sequence: MAWHRNIKTRGAMVVAAVTLGASGVAAAQSMSTNSASFNAGYGRSSGQESRMVEYSTRDANGNRVVVDGVMLTGSDQSVFSSSRSSGSLDAYSGVGAVGGYAGSTAIGNNLTVITQGNNNTVIVNSSQVNSGNVTAGANVVKGGTPK
What is the function of this protein?
Involved in attachment of the holdfast to the cell.  The holdfast is a structure that allows the bacteria to firmly adheres to surfaces.
What are the official names of this protein?
Holdfast attachment protein A, Hfa-A, Protein HfaA.
Protein: PHOSP_SV41
Sequence: MAEEPTYTAEQVNDVVHAGLGTVDFFLSRPVDGQSSLGKGSVPPGITAVLTNAAELKAKTAAAAPVKPKRKKIQHMTPAYTIADNGDPNRLPANTPIANPLIPIERPPGRMTDLDLATGTVTQGTYKGVELAKAGKNALLTRFSSGPSLTDQASSKDPNFKRGGEKLTDATKADIGGSGASPGSETKLRFMSGAIQHVPQLLPLTASSPVLVEPAPIGAENVKEIIEILRGLDLRMQSLEGKVDKILATSATITALKNEVTSLKANVATVEGMMTTMKIMDPSTPTNVPVEKIRKNLKDTPVIISGPLSESHITEGSDMIVLDELARPSLSSTKKIVRRPEPKKDLTGMKLMLIQLANDCMGKPDQKAEIVAKIHAATREAQLLDIKRSIIKSAI
What is the function of this protein?
Essential component of the RNA polymerase and the nascent chain assembly complex.  Also required during RNA synthesis.
What are the official names of this protein?
Phosphoprotein, Protein P.
What is the protein family that this protein belongs to?
Belongs to the rubulavirus/avulavirus P protein family.
Protein: CEP41_HUMAN
Sequence: MSLRRHIGNPEYLMKRIPQNPRYQHIKSRLDTGNSMTKYTEKLEEIKKNYRYKKDELFKRLKVTTFAQLIIQVASLSDQTLEVTAEEIQRLEDNDSAASDPDAETTARTNGKGNPGEQSPSPEQFINNAGAGDSSRSTLQSVISGVGELDLDKGPVKKAEPHTKDKPYPDCPFLLLDVRDRDSYQQCHIVGAYSYPIATLSRTMNPYSNDILEYKNAHGKIIILYDDDERLASQAATTMCERGFENLFMLSGGLKVLAQKFPEGLITGSLPASCQQALPPGSARKRSSPKGPPLPAENKWRFTPEDLKKIEYYLEEEQGPADHPSRLNQANSSGRESKVPGARSAQNLPGGGPASHSNPRSLSSGHLQGKPWK
What is the function of this protein?
Required during ciliogenesis for tubulin glutamylation in cilium.  Probably acts by participating in the transport of TTLL6, a tubulin polyglutamylase, between the basal body and the cilium.
What are the official names of this protein?
Centrosomal protein of 41 kDa, Cep41, Testis-specific gene A14 protein.
What is the protein family that this protein belongs to?
Belongs to the CEP41 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Note=Localizes mainly to the cilium basal body and in primary cilia.
Protein: C562_SALTY
Sequence: MRKSLLAILAVSSLVFGSAVFAADLEDNMDILNDNLKVVEKTDSAPELKAALTKMRAAALDAQKATPPKLEDKAPDSPEMKDFRHGFDILVGQIDGALKLANEGNVKEAKAAAEALKTTRNTYHKKYR
What is the function of this protein?
Electron-transport protein of unknown function.
What are the official names of this protein?
Soluble cytochrome b562, Cytochrome b-562.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b562 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: NUOC_DEIGD
Sequence: MTELPERSAATTGGAKTARDVSSLIAELGLTAEDSIEPTALVPPERLREVALALRDRGFMLMDTVGVDYGAFPERIPARFCVLHNVYHIKDRCRLFLRVWLEEGQALDSLYPVWRAANYLEREVYDLFGIEFVGHPDLRKILTPDDLEGHPLRKDFPLGESPTLFREGRFIDPPAFRAGLSGQNAGLTGWRGEFRRGERGDRVPPVLPEGGPQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YI066_YEAST
Sequence: MRIQKQQYTISSNSRINLLGILVLNVVCGKSSIFFSHPQRLGKLGGSSLGSTGPFQTLSINFCIGCFLFNSNHFDLLFSLPSSSSILSMSVLEKFCSCIDSVTRCCPSQSLETPGSVASHVVLALSSKCTPIQFNAKWSISHKSNTG
What are the official names of this protein?
Putative uncharacterized membrane protein YIL066W-A.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.