PharMolix/UniProtQA huggingface dataset:
Protein: PUF3_YEAST
Sequence: MEMNMDMDMDMELASIVSSLSALSHSNNNGGQAAAAGIVNGGAAGSQQIGGFRRSSFTTANEVDSEILLLHGSSESSPIFKKTALSVGTAPPFSTNSKKFFGNGGNYYQYRSTDTASLSSASYNNYHTHHTAANLGKNNKVNHLLGQYSASIAGPVYYNGNDNNNSGGEGFFEKFGKSLIDGTRELESQDRPDAVNTQSQFISKSVSNASLDTQNTFEQNVESDKNFNKLNRNTTNSGSLYHSSSNSGSSASLESENAHYPKRNIWNVANTPVFRPSNNPAAVGATNVALPNQQDGPANNNFPPYMNGFPPNQFHQGPHYQNFPNYLIGSPSNFISQMISVQIPANEDTEDSNGKKKKKANRPSSVSSPSSPPNNSPFPFAYPNPMMFMPPPPLSAPQQQQQQQQQQQQEDQQQQQQQENPYIYYPTPNPIPVKMPKDEKTFKKRNNKNHPANNSNNANKQANPYLENSIPTKNTSKKNASSKSNESTANNHKSHSHSHPHSQSLQQQQQTYHRSPLLEQLRNSSSDKNSNSNMSLKDIFGHSLEFCKDQHGSRFIQRELATSPASEKEVIFNEIRDDAIELSNDVFGNYVIQKFFEFGSKIQKNTLVDQFKGNMKQLSLQMYACRVIQKALEYIDSNQRIELVLELSDSVLQMIKDQNGNHVIQKAIETIPIEKLPFILSSLTGHIYHLSTHSYGCRVIQRLLEFGSSEDQESILNELKDFIPYLIQDQYGNYVIQYVLQQDQFTNKEMVDIKQEIIETVANNVVEYSKHKFASNVVEKSILYGSKNQKDLIISKILPRDKNHALNLEDDSPMILMIKDQFANYVIQKLVNVSEGEGKKLIVIAIRAYLDKLNKSNSLGNRHLASVEKLAALVENAEV
What is the function of this protein?
RNA-binding protein involved in post-transcriptional regulation.  Negatively regulates expression of COX17 by binding to the 3'-UTR of COX17 mRNA.  Promotes decay of COX17 mRNA by enhancing its rate of deadenylation and subsequent turnover.  Predominantly binds to mRNAs encoding mitochondrial proteins and localizes them to the vicinity of mitochondria for translation.  Regulates mitochondrial biogenesis, motility and morphology.
What are the official names of this protein?
mRNA-binding protein PUF3, Pumilio homology domain family member 3.
What is the protein family that this protein belongs to?
Belongs to the PUF3 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Localizes to multiple discrete foci in the cytoplasm.
Protein: RPOZ_STRR6
Sequence: MLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSEKSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGEKI
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: VE1_MMPV1
Sequence: MDPEGTPGEGVGCTGWFNVEAIVERKTGDVVSEDEDDTEDTGIDLVDFIDDTCGSVQTGDEAPGALLHAQETQAHAEAVQVLKRKFVGSPAVSPLGNYNPCVDRDLSPRLNEISLNQGSGQAKRRLFLPDSGYGNTEVETSLLQVAGGGGQDVQAGGKENTRPDDGGGDATQLLRCSNLKATLLSKFKSVYGVSFSELVRSFKSDRTTCADWVVGAAGVHHSVAEGLKQLIQPFCSYAHIQCLTCDWGVYLLLLARFKCGKNRLTVSKCMSTLLNVQETHMLIEPPKLRSAAAALYWYRTGISNVSEVIGETPEWITRQTMFQHGLEDSIFDLSEMVQWAYDHDFTDDSVIAYEYAQLAGIDSNAAAFLKSNAQAKYVKDCATMCRHYKRAERQQMTMSQWIKQRCEKTDDGGDWRPIVQFLRYQGVEFIAFLAALKLFLKGIPKKNCIVLFGPPNTGKSYFGMSLIHFLQGSIISYVNSNSHFWLQPLADAKVAMLDDATPQCWSYIDNYLRNALDGNPISVDRKHKNLVQMKCPPLLITSNTNAGQDDRWMYLHSRMVVFTFEQPFPFDQNGNPVYELNDKNWKSFFSRTWSRLDLQEEEETENDGSTCRAFKCVAGQNLRTV
What is the function of this protein?
ATP-dependent DNA helicase required for initiation of viral DNA replication.  It forms a complex with the viral E2 protein.  The E1-E2 complex binds to the replication origin which contains binding sites for both proteins.  During the initial step, a dimer of E1 interacts with a dimer of protein E2 leading to a complex that binds the viral origin of replication with high specificity.  Then, a second dimer of E1 displaces the E2 dimer in an ATP-dependent manner to form the E1 tetramer.  Following this, two E1 monomers are added to each half of the site, which results in the formation of two E1 trimers on the viral ori.  Subsequently, two hexamers will be created.  The double hexamer acts as a bi-directional helicase machinery and unwinds the viral DNA and then recruits the host DNA polymerase to start replication.
What are the official names of this protein?
Replication protein E1, ATP-dependent helicase E1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E1 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: VP1_POVJC
Sequence: MAPTKRKGERKDPVQVPKLLIRGGVEVLEVKTGVDSITEVECFLTPEMGDPDEHLRGFSKSISISDTFESDSPNRDMLPCYSVARIPLPNLNEDLTCGNILMWEAVTLKTEVIGVTSLMNVHSNGQATHDNGAGKPVQGTSFHFFSVGGEALELQGVLFNYRTKYPDGTIFPKNATVQSQVMNTEHKAYLDKNKAYPVECWVPDPTRNENTRYFGTLTGGENVPPVLHITNTATTVLLDEFGVGPLCKGDNLYLSAVDVCGMFTNRSGSQQWRGLSRYFKVQLRKRRVKNPYPISFLLTDLINRRTPRVDGQPMYGMDAQVEEVRVFEGTEELPGDPDMMRYVDKYGQLQTKML
What is the function of this protein?
Forms an icosahedral capsid with a T=7 symmetry and a 40 nm diameter.  The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with VP2 or VP3 proteins.  Interacts with a N-linked glycoprotein containing terminal alpha(2-6)-linked sialic acids on the cell surface to provide virion attachment to target cell.  The serotonergic receptor 5HT2AR also acts as a cellular receptor for JCV on human glial cells.  Once attached, the virions enter predominantly by a ligand-inducible clathrin-dependent pathway and traffic to the ER.  Inside the endoplasmic reticulum, the protein folding machinery isomerizes VP1 interpentamer disulfide bonds, thereby triggering initial uncoating.  Next, the virion uses the endoplasmic reticulum-associated degradation machinery to probably translocate in the cytosol before reaching the nucleus.  Nuclear entry of the viral DNA involves the selective exposure and importin recognition of VP2/Vp3 nuclear localization signal.  In late phase of infection, neo-synthesized VP1 encapsulates replicated genomic DNA at nuclear domains called promyelocytic leukemia (PML) bodies, and participates in rearranging nucleosomes around the viral DNA.
What are the official names of this protein?
Major capsid protein VP1, Major structural protein VP1.
What is the protein family that this protein belongs to?
Belongs to the polyomaviruses coat protein VP1 family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=Virions are efficiently assembled at nuclear domain 10 (ND10), which is also known as promyelocytic leukemia (PML) nuclear bodies.
Protein: DDLB_BRUSU
Sequence: MTGKHVAVLMGGFSSERSVSLSSGVACATTLEECGYRVTRIDVDRNVASILVELKPDVVFNALHGPFGEDGAIQGVLEYLQIPYTHSGVLASALAMDKDRAKKVAAAAGVVVAPSRLMNRFDIGSQHPMKPPYVVKPVREGSSFGVVIVKEDQPHPPQVIGSADWKYGDEVMVEGYIAGRELTCAVMGDRAMDVCEIIPVGYQFYDYDSKYVAGASTHVSPAKILPNIYQKIQTMALTAHRAIGCRGVSRSDFRFDDRFSEEGEVVWLEINTQPGMTPTSLVPDIAKAAGISFAELLSWMVEDASCLR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase B, D-Ala-D-Ala ligase B, D-alanylalanine synthetase B.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_BACHK
Sequence: MRKPIIAGNWKMNKTLSEAVSFVEEVKGQIPAASAVDAVVCSPALFLERLVAATEGTDLQVGAQNMHFEKNGAFTGEISPVALSDLKVGYVVLGHSERREMFAETDESVNKKTIAAFEHGLTPIVCCGETLEERESGKTFDLVAGQVTKALAGLTEEQVKATVIAYEPIWAIGTGKSSSSADANEVCAHIRKVVAEAVSPEAAEAVRIQYGGSVKPENIKEYMAQSDIDGALVGGASLEPASFLGLLGAVK
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS8_PSEA6
Sequence: MAEPVNNLIDLLLNDNIKGLKPYESARRLFSGAGNKQQVWLNANESPFANDFTIDAERFNRYPDCQPPAVIDAYAAYAGVQPEQLLVSRGADEGIELLIRAFCTPGKDSVLICPPTYGMYAISAETCDVGIERAGLNDDFSLNVDAIKAFKGKVNLVFICSPNNPTGTSVDKNQLLEVVEHFADSAIVVIDEAYIEFDKDNSWAAELTHYPNIAILRTLSKAFALAGLRCGFTLAQAPVIQALMKVIAPYPIPEPVAQIAAQALSSEGLVTLEQQVAVINQEKALLKSALAEIADVELVGDDKANFILFRTPQKSALMSHLVASGILIRDQSKQINLDNCLRITVGSPEQNKQLLSEISRFFTLQTSTQEA
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: MCJB_ECOLX
Sequence: MIRYCLTSYREDLVILDIINDSFSIVPDAGSLLKERDKLLKEFPQLSYFFDSEYHIGSVSRNSDTSFLEERWFLPEPDKTLYKCSLFKRFILLLKVFYYSWNIEKKGMAWIFISNKKENRLYSLNEEHLIRKEISNLSIIFHLNIFKSDCLTYSYALKRILNSRNIDAHLVIGVRTQPFYSHSWVEVGGQVINDAPNMRDKLSVIAEI
What is the function of this protein?
Along with McjC, necessary and sufficient to process the inactive microcin J25 (McjA) precursor into the active peptide.
What are the official names of this protein?
Microcin J25-processing protein McjB.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EPIC3_PHYIN
Sequence: MAFTRSIALFAGLALAASSAQEATILGGYTQKNATSDDIELLTQATSSANMYNKNVDTRICLIAIENLETQTVAGTNYKFQVAGCPVETDDELGACDDRNCDYSSYNIVIFSQPWSDTIEVTSITPAEYQG
What is the function of this protein?
Secreted effector that interacts with and inhibits host apoplastic pathogenesis-related papain-like cysteine proteases (Probable).  Inhibition of host proteases by a pathogen extracellular protease inhibitor forms a specific type of defense-counterdefense mechanism between plants and microbial pathogens (Probable).
What are the official names of this protein?
Cystatin-like cysteine protease inhibitor EPIC3, Extracellular protease inhibitor with cystatin-like domain protein 3, Secreted effector EPIC3.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
What are the subcellular locations of this protein?
Secreted. Note=Localizes to host apoplast where it targets defense proteases for inhibition.
Protein: MNMA_HELPS
Sequence: MKIAVLLSGGVDSSYSAYSLKEQGHELVGIYLKLHASEKKHDLYIKNAQKACEFLGIPLEVLDFQKDFKSAVYDEFISAYEEGQTPNPCALCNPLMKFGLALDHALKLGCEKIATGHYARVKEIDKVSYIQEALDKTKDQSYFLYALEHEVIAKLVFPLGDLLKKDIKPLALNAMPFLGTLETYKESQEICFVEKSYIDTLKKHVEVEKEGVVKNLQGEIIGTHKGYMQYTIGKRKGFSVKGALEPHFVVGIDAKKNELIVGKKEDLATHSLKAKNKSLTKDFKNGEYSIKARYRSVPTKAFVSLRDEAIEVEFEEPFYGVAKGQALVVYKDDILLGGGVIV
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEND_VIBA3
Sequence: MNHDQAVLNRVWCNTLLEELARSGVEHVCVAPGSRSTPLTLEAEANPKLTLHTHFDERGLGFLALGLAKASNKPVAVIVTSGTAVANLLPATAESGLTREKLILLTSDRPIDLVDCGANQAIQQQGIFSSHVESALNLPSPTTQISLNWLLTSVDNALAKQRNVGGAIHINCPFPEPLYSANSAEMYAEYTSSISGWKSGTACYSQTFLPNQVNTQPIAPSEYLGRKGVVILGSLDIEQATKAQQFATALGWPVFCDPQSGVTSDWKHYDLWMQSDVAKAQLNQCDFILQFGERVVSKRLNHWIKSQASSFCSSQYIVVSPDTHRINQDHLPQTHIVADIESWVSEQHLPTLLGQHAGWAAPLVEIANTVQQLALAQISNNDQLTELSVAVDLSTRLKDRELFVGNSLMVRLVDMLSSISANQVYSNRGASGIDGLVATAAGVVKANQNPLIMLIGDTSLLYDLNSLALFTHNVTPMVIVVTNNDGGAIFDLLPVPEQQKQSLYQMPHGFSFEHAAAQFQLGYAAPETLNGYQTIVEQHFEQGQGTLLVEVKTPPEQAATLLKQFSAMLIEALA
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: MNMG_BURVG
Sequence: MLFPTEFDVIVVGGGHAGTEAALASARMGAKTLLLTHNIETLGQMSCNPSIGGIGKGHLVKEVDALGGAMAAATDESGIQFRILNSSKGPAVRATRAQADRILYKAAIRHRLENQPNLWLFQQAVDDLMVEGDRVVGAVTQIGIRFRARAVVLTAGTFLDGKIHVGLNNYTGGRAGDPAAVSLSARLKELKLPQGRLKTGTPPRIDGRSIDFSKLDEQPGDLDPIPVFSFLGRAEQHPQQLPCWVTHTNERTHDIIRGGLDRSPMYTGVIEGVGPRYCPSIEDKIHRFASKESHQIFLEPEGLTTNEFYPNGISTSLPFDVQLELVHSMRGLENAHILRPGYAIEYDYFDPRALKASLETKAINGLFFAGQINGTTGYEEAAAQGLLAGLNAGRYVQEKDAWCPRRDQAYLGVLVDDLVTRGVAEPYRMFTSRAEYRLSLREDNADMRLTEIGRELGLVDDVRWDAFSRKRDAVSRETERLKSTWVTPKTLPPEEATALLGKPIDHEYSLAELLRRPGISYDGVCGLKGGECGPVEPLADEPVLLGQIKEQVEIGIKYQGYIERQANEIERNDANENTRLPDGIDYREVRGLSFEVSQKLNEFRPETIGQASRISGVTPAAISLLMVHLKRRGLGRRNGAAAETTEQGGDTVPTQQ
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y668_EXISA
Sequence: MSAYLFLLMLVLIGVISNNQSVIIASSVLLIIKAIGFGDQLFPTLASKGISWGVTIITIAVLVPIATGDIGFKELWNSIKGPVGIVAFASGMFVAIAAGQGVQLMRVDPVVTTALLAGTILAVGFMKGIPVGPLVGAGIAALILGGYQVIEKWF
What are the official names of this protein?
UPF0756 membrane protein EAT1b_0668.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EFG_SYMTH
Sequence: MSRQVSLDRLRNIGIMAHIDAGKTTTTERILFYTGRTHKLGETHEGAATMDFMVQEQERGITIQSAATTCSWKDHRINIIDTPGHVDFTVEVERSLRVLDGAVAVFCAKGGVEPQSETVWRQADKYGVPRLAYVNKMDTIGADFFRVIRMMEERLGARPVPIQIPIGAEDTFRGVVDLVRNVAIMYYDDLGKDIREEPIPEDMRELVEQYRTRMIEAATEADDALMEKYLMGEELTVEEIKRGLRKLTVECKINPVCCGSSYKNKGVQPLLDAIVDYLPSPLDIPPVQGTDPETGEPAERKADDNEPFSALAFKVVSDPYVGKLCFFRVYSGQLKSGSYVLNATKGKRERIGRLVRMHANHREEVEVVETGDIAAAVGLKDTGTGDTLCTDAAPVILESMEFPEPVIQLAVEPKTKADQDKLSTALLKLAEEDPTFRMFTDPETGQTIIAGMGELHLEIIVDRLQREFKVGVNVGKPQVSYRETVRGRVENVEGRFVRQSGGRGQYGHVVINLEPAEPGSGFIFENKIVGGVIPKEFIGPVEQGIKEALQNGVLAGYPMIDVKVELVFGSYHEVDSSEAAFKIAGSMALKAAAQKAQPVLLEPYMRVEVTVPEEYMGDVIGDLNARRGRIEGMEARGNAQVIRAQVPLAEMFGYATDLRSRTQGRGVYSMQFDHYEEVPPNVAKPIIEKAQGKA
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: A31_LOXLA
Sequence: MYVHLALILGCWTVVLQGAETDVGERADNRRPIWNLAHMVNAVKQIPTFLDLGANALEADVTFKGSVPTYTYHGTPCDFGRDCIRWEYFNVFLKTLREYTTPGNAKYRDGFILFVLDLKTGSLSNDQVRPAGENVAKELLQNYWNNGNNGGRAYVVLSLPDIGHYEFVRGFKEVLKKEGHEDLLEKVGYDFSGPYLPSLPTLDATHEAYKKAGVDGHIWLSDGLTNFSPLGDMARLKEAIKSRDSANGFINKIYYWSVDKYSTTRTALDVGVDGIMTNYPNVLIDVLNEDGYKDNYRLATYDDNPWETYKK
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (PubMed:24472346).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Shows complement-dependent hemolysis (PubMed:21692149).  Also induces dermonecrosis, vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin, Phospholipase D isoform 1, LlPLD1, PLD1, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class I subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DDX41_DICDI
Sequence: MSEESRKHDIEEQHIEKWIPLKERKLNQIKSKLNNLKQQQPQQHSQQQENEQNNATATNTNITNTTTTTTTTTTTTTSSNNDNNFEDEKKPIYQQSQSLLDQKFEMIKKQENKTQRELQQGGTIIENDVNSSNNNNNNGEENKIKEEKRLDMEESDILKSLKTFKPLVSVKDRAKDVIYTDSIKTNWRAPRYILERDEKDHQKVRDQLNIITDGEDIPPPITTFKEMKIPKPVIDVLLEKGIKKPSPIQVQGLPVILSGRDMIGIAYTGSGKTLVFTLPMVLFALEEECKLPIIQGEGPFGLILCPSRELARQTYDLVNSFTNALHKNGGHPQLRTLLAIGGIDLREQEHIFKKGVHMIIATPGRLLDLLNKKKINFKLCKYLGLDEADRLIDLGFEDDIRSVLDNFTNQRQTLLFSATMPKKIQEFARSALVLPVEVNVGRAGAANLNVTQEVEFVKPEAKIVYLLECLQKTPPPVLIFCENKKDVDDIYEYLLLKQVEAVSIHGDKSQDERESAIKAFREGKKDVLVATDVASKGLDFPEIQHVINFDMPREIENYIHRIGRTGRRGNKGVATTFINKNNTESLLLDLKYLLIEAKQKVPPALLEIPDDNQYLQKLQDRNGNTGGGADDDDTKPCEYCDGRGHRLVNCPKLKKQAGPKRDFFGSGGGDW
What are the official names of this protein?
Probable ATP-dependent RNA helicase ddx41, DEAD box protein 41.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX41 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS20_AQUAE
Sequence: MPNTRQAKKRMRRDAKRRLRNRYHLSRMRTYIKNFRRMIENGEIDKAKEYINEVISVIYHTAAKGVIHKNEAARRASRVYKLLNKALQQQQAQA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: PP1RB_RAT
Sequence: MAEAGAGGLSETVTETTVTVTTEPENRSLTIKLRKRKPEKKVEWSSDTVDNEHMGRRSSKCCCIYEKPRAFGESSTESDEDEEEGCGHTHCVRGHRKGRRPTTPGPTPTTPPQPPDPSQPPPGPMQH
What is the function of this protein?
Atypical E3 ubiquitin-protein ligase which ubiquitinates TLR2 at 'Lys-754' leading to its degradation by the proteasome.  Plays a role in regulating inflammatory cytokine release and gram-positive bacterial clearance by functioning, in part, through the ubiquitination and degradation of TLR2.  Inhibitor of protein phosphatase 1.
What are the official names of this protein?
E3 ubiquitin-protein ligase PPP1R11, Protein phosphatase 1 regulatory subunit 11.
Protein: MYSB_ACACA
Sequence: MGKAAVEQRGVDDLVLMPKITEQDICANLEKRYFNDLIYTNIGPVLISVNPFRRIDALLTDECLHCYRGRYQHEQPPHVYALAEAAYRGVKSENINQCVIISGESGAGKTEASKLVMQYVAAVSGNSGGVDFVKHSNPLLEAFGNAKTLRNNNSSRFGKYFEIHFNRLGEPCGGRITNYLLEKSRVTFQTRGERSFHIFYQLLAGASDAEAQEMQLYAPENFNYLNQSACYTVDGIDDIKEFADTRNAINVMGMTAEEQRQVFHLVAGILHLGNVAFHDGGKGTAAVHDRTPFALKNALLFRVLNTGGAGAKKMSTYNVPQNVEQAASARDALAKTIYSRMFDWIVSKVNEALQKQGGSGDHNNNMIGVLDIFGFEIFEQNGFEQFCINYVNEKLQQYFIELTLKAEQEEYVNEGIQWTPIKYFNNKVVCELIEGKRPPGIFSLLDDICFTMHAQSDGMDGKFLQKCQGGFPSHLHFRGMNNAFSIKHYAGEVTYEAEGFCEKNKDTLFDDLIAVIQESENRLLVSWFPEDTKQLQKKRPTTAGFKLKTSCDALMEALSRCSPHYIRCIKPNDNKAYHDWDATRTKHQVQYLGLLENVRVRRAGFAYRAEFDRFLRRYKKLSPKTWGIWGEWSGAPKDGCQTLLNDLGLDTSQWQLGKSKVFIRYPETLFHLEECLDRKDYDCTLRIQKAWRHWKSRKHQLEQRKMAADLLKGKKERQRHSVNRKYEFDYINYDANYPLQDCVRSSGRDKEATAFTDQVLVLNRRGKPERRDLIVTNEAVYFAMRKKKSGQVVYNLKRRIPLGEIASLSLSTLQDNYVVIHHNQYDMVFENDKKTEIVTILMENYKMSGGRDLPVNFNDNITYKASNGAQRRLTFSKNESASAQPSIKKSRANIQIGIATGLPKETDSSPPNWTPSGGGGGYGGGRGGGGGGRGAAGGGRGGFGGGGGGGYSQPVAQAQPVAQVPQPVAAVPSAGRGGPGMGGPGAGRGGPGMGRGGPGMGGPGAGRGGPGMGGPGGPGRGGPGGPGAGRGGPGGPGAGRGGPGMGGPGGAGRGGPGAGRGGPGMGGPGAGRGGPGAGRGAAPAPAPAAPAKPQVKALYDYDAQTGDELTFKEGDTIIVHQKDPAGWWEGELNGKRGWVPANYVQDI
What is the function of this protein?
Myosin is a protein that binds to F-actin and has ATPase activity that is activated by F-actin.
What are the official names of this protein?
Myosin heavy chain IB, Myosin heavy chain IL.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
Protein: EIF3L_MOUSE
Sequence: MSYPADDYESEAAYDPYAYPGDYDMHTGDPKQDLAYERQYEQQTYQVIPEVIKNFIQYFHKTVSDLIDQKVYELQASRVSSDVIDQKVYEIQDIYENSWTKLTERFFKNTPWPEAEAIAPQVGNDAVFLILYKELYYRHIYAKVSGGPSLEQRFESYYNYCNLFNYILNADGPAPLELPNQWLWDIIDEFIYQFQSFSQYRCKTAKKSEGEMDFLRSNPKVWNVHSVLNVLHSLVDKSNINRQLEVYTSGGDPESVAGEYGRHSLYKMLGYFSLVGLLRLHSLLGDYYQAIKVLENIELNKKSMYSRVPECQVTTYYYVGFAYLMMRRYQDAIRVFANILLYIQRTKSMFQRTTYKYEMINKQNEQMHALLAIALTMYPMRIDESIHLQLREKYGDKMLRMQKGDPQVYEELFSYACPKFLSPVVPNYDNVHPNYHKEPFLQQLKVFSDEVQQQAQLSTIRSFLKLYTTMPVAKLAGFLDLTEQEFRIQLLVFKHKMKNLVWTSGISALDGEFQSASEVDFYIDKDMIHIADTKVARRYGDFFIRQIHKFEELNRTLKKMGQRP
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis.  The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC).  The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition.  The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit L, eIF3l, 66 kDa tyrosine-rich heat shock protein, 67 kDa polymerase-associated factor, Eukaryotic translation initiation factor 3 subunit 6-interacting protein, Eukaryotic translation initiation factor 3 subunit E-interacting protein, HSP-66Y, PAF67.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit L family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHED2_SHEON
Sequence: MENMAFNQRTVVMIGPGEHYVTAKNEVIKTLLGSCVAVCLYDPKAQVIGMNHFLLAADRRKFTHFLDSRAGYYGVHAMEILINAMLKRGAQRKYLQSKIFGGANVLSLCADNILNHYDIGGMNIDFVRHFLQRERIPIISEDIGGHCGRVIYFDPTDYSVYRSLIEHKYEEIASLQDEEYRYFNQASEDIHSSGVPVVIWSD
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD 2.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: EFTS_ECO45
Sequence: MAEITASLVKELRERTGAGMMDCKKALTEANGDIELAIENMRKSGAIKAAKKAGNVAADGVIKTKIDGNYGIILEVNCQTDFVAKDAGFQAFADKVLDAAVAGKITDVEVLKAQFEEERVALVAKIGENINIRRVAALEGDVLGSYQHGARIGVLVAAKGADEELVKHIAMHVAASKPEFIKPEDVSAEVVEKEYQVQLDIAMQSGKPKEIAEKMVEGRMKKFTGEVSLTGQPFVMEPSKTVGQLLKEHNAEVTGFIRFEVGEGIEKVETDFAAEVAAMSKQS
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YORR_TTV1K
Sequence: MGVEVLGGIFSKRFTSIVGSFIWFIITPILLYLPWPLAMLGFLTLYGALPFGVGIVNWPYPRDACGC
What are the official names of this protein?
Uncharacterized 7.4 kDa protein.