PharMolix/UniProtQA huggingface dataset:
Protein: VP3_BTV2A
Sequence: MAAQNEQRPERIKTTPYLEGDVLSSDSGPLLSVFALQEIMQKVRQVQADYMTATREVDFTVPDVQKILDDIKALTVEQVYKIVKVPSISFRHIVMQSRDRVLRVDTYYEEMSQVGDVITEDEPEKFYSTIIKKVRFIRGKGSFILHDIPTRDHRGMEAAEPEVLGVEFKNVPPVLTAEHRAMIQSALDGSIIENGNVATRDVDVFIGACSEPIYRIYNRLQGYIEAVQLQELRNSIGWLERLGQRKRITYSQEVLTDFRRQDTIWVLALQLPVNPQVVWDVPRSSIANLIMNIATCLPTGEYIAPNPRISSITLTQRITTTGPFAILTGSTPTAQQLNDVRKIYLALMFPGQIILDLKIDPGERMDPAVRMVAGVVGHLLFTAGGRFTNLTQNMARQLDIALNDYLLYMYNTRVQVNYGPTGEPLDFQIGRNQYDCNVFRADFATGTGYNGWATIDVEYRDPAPYVHAQRYIRYCGIDSRELINPTTYGIGMTYHCYNEMLRMLVAAGKDSEAAYFRSMLPFHMVRFARINQIINEDLHSVFSLPDDMFNALLPDLVAGAHQNADPVVLDVSWISLWFAFNRSFEPTHRNEMLEIAPLIESVYASELSVMKVDIRHLSLMQRRFPDVLIQARPSHFWKAVLNDSPEAVKAVMNLSHSHNFINIRDMMRWVLLPSLQPSLKLALEEEAWAAANDFEDLMLTDQVYMHRDMLPEPRLDDIERFRQEGFYYTNMLEAPPEIDRVVQYTYEIARLQADMGQFRAALRRIMDDDDWVRSDGVLRTVRVKFFDARPPDDILQGLPFSYDTNEKGGLSYATIKYATETTIFYLIYNVEFSNTPDSLVLINPTYTMTKVFINKRIVERVRVGQILAVLNRRFVAYKGKMRIMDITQSLKMGTKLAAPTV
What is the function of this protein?
The VP3 protein is one of the five proteins (with VP1, VP4, VP6 and VP7) which form the inner capsid of the virus.
What are the official names of this protein?
Core protein VP3, Major inner capsid protein.
What is the protein family that this protein belongs to?
Belongs to the orbivirus VP3 family.
What are the subcellular locations of this protein?
Virion.
Protein: GLYA1_MYCBO
Sequence: MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFAPRAVLQAQGSVLTNKYAEGLPGRRYYGGCEHVDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLANGGHLTHGMRLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYPRVLDFAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSGLIVGKQQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMAPDVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPPMVTSGLRIGTPALATRGFGDTEFTEVADIIATALATGSSVDVSALKDRATRLARAFPLYDGLEEWSLVGR
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase 1, SHMT 1, Serine methylase 1.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA2_PHOPR
Sequence: MQLNSNEISDLIRQRIATFNVTSQARNEGTIVSVSDGIISINGLADVMQGEMIELPGNRYALALNLERHSVGAVVMGPYSDLAEGLKVKGTGRILEVPVGRGLLGRVVNTLGQPIDGKGAIENDGYSPVEIIAPGVIERQSVDQPIQTGYKAVDAMVPIGRGQRELIIGDRQTGKTAMAIDAIINQKDSGIKCVYVAIGQKASTIANVVRKLEEHDALKNTIVVVATASDAAALQYLAPYSGCTMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLKRPPGREAFPGDVFYLHSRLLERASRVNVSYVERFTKGKVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLQTHLFNSGLRPAVDPGISVSRVGGAAQTKIVKKLSGGIRTALAQYRELAAFAQFSSDLDDATRKQLDHGEKVTELMKQKQYAPMSVAEQALAIFSAEKGYLGDVPLASIGDFESALMAYAKSEHSALLDTINKTGQYDDDIEQSLHKLLKTFTATQSW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha 2, ATP synthase F1 sector subunit alpha 2, F-ATPase subunit alpha 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS20_BACMK
Sequence: MANIKSAIKRAKLSEERRSHNASIKSDMRTAVKTVETLVTNNDLENAKEAFKTASKKLDKAARKGLIHQNAAARQKSRLAKQVNA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: HIS5_GLOVI
Sequence: MARTPNIALVDYGVGNLHSARKGLEAMGARVTLSGQPLTLSAADGVVLPGVGSFDTAITRLNDRGLGDAIIQLVRAGQPMLGICLGLQVLFDSSEEGRLPGLGLLPGRVRRFRSEPGLTIPHVGWNQLHFDNVDCPLWRDLAAGGWVYFVHSYYVDPARAEDRAASAVHGSQHFTAAVCRDNLMAVQFHPEKSADTGLRILKNFVERAASRSAAEVAARCATRPPA
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URK_STREM
Sequence: MLKKPIIIGVTGGSGGGKTSVSRAILNSFPNARIAMIQHDSYYKDQSHISFEERVKTNYDHPLAFDTDFMIQQLKELLAGRPVDIPIYDYKEHTRSNRTFRQEPQDVIIVEGILVLEDERLRELMDIKLFVDTDDDIRIIRRIQRDMVERGRSLESIIEQYTSVVKPMYHQFIEPSKRYADIVIPEGVSNVVAIDLINTKIASILGEL
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURC_WIGBR
Sequence: MNNLFFSKILRSDNIHFVGIGGVGMGALAEICIKLGYKISGSDIKENLITKKLSVLGAKIYNQHCANNIIESTIIVVSSAIKEDNLEIIYAKKLNIPVVKRAEFLSELMRFKYGIIVSGTHGKTTTTSIISYIYKEAKLFPTYLYGGRLNNSDDYGNLGNSKYWISEADESDNSFLFFRPIISVVTNIEKDHLESYQGNFKKLKESFIKFLHNIPFYGYSVLCLDDIEIKKIIPLINKKIVTYGFNRNSDFCITKFFQSNKKIIFIVYIKHQKRYLKFVSNLLGKHNALNITAAITIAIKEGIKYNIILNSIKKFPGINRRFDFINKYDLSNLNNKKGTITIVDDYGHHPTELKLTIKSVKKIWNKRRLIMIFQPHKYTRTKYLYNYFVKVLSTVDILLIMEIYSAGENPIYKINSKNLCQSIMALKRSHVIFIPNEKFLFKKLELLLKNNDILLLQGAGTIENIFKKLTSKLLL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_CLOBB
Sequence: MISAKSVKELRERTGAGMMDCKKALTETDGDIEKAVEVLREKGLAAAAKKSGRVAAEGLVKTYISEDKKSGAIVELNCETDFVAANEDFIAFADALAKIATSTSATTVEELVNEKFDSEATIQEALTGLIARLGENMTVRRFVKFAVDNGVVKSYIHGGGRIGVLVEVACDVESPAVEEVAKELCMQIAAANPLFLSKEEVDQDSIEKEKEIYRVQALNEGKPEKIVEKMVMGRIQKYYKEVCLLEQLWVKDGDKTITKFIDEKAKEAGSAIKVNRFVRFERGEGIEKVEENFAEEVAKQLGK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GARS_BOMMO
Sequence: MRHVLSLVYKCSVFSKQVTVFSNHLRLSHSQQWGSNKLHRKIKIPNPFREIIMADPKIEEILAPLRANVKEQGDLVRKLKEEKAPEIDIKKAVAELKTRKKILEDKELSLAPAEDLFDRAKMEDLIKRRFFYDQSFAIYGGITGQFDFGPMGCALKSNMIHLWKKFFILQEQMLEVECSILTPEPVLKASGHVERFADLMTKDIKTGECFRLDHLIKGHLEKIKSDKNTKIELKAEIEDILIKLDGMNADEMSALMKRFEMKSPISGNDLTPPIEFNLMFNTQIGPSGLVKGFLRPETAQGIFVNFKRLLEFNQGRLPFAAAQIGNSFRNEISPRSGLLRVREFTMCEIEHFCDVKEHPKFESVKNTQSLLYSADNQEQGKPADLTTIGDAVCKGIVNNETLGYFMARIHMYMLAVGIDPKRLRFRQHMGNEMAHYACDCWDAECLSSYGWIECVGCADRSAYDLTQHTKATGIRLAAEKKLPAPKQIEVVEAIANNGRIGKAFKKDSQAINDTLATLDNAALEEMQKELDSNGEYTLITARGEFKLTPSLVNVKKTQKTIHVEEIIPSVIEPSFGVGRILYCILEHNFRMREGDEQRTYFSLPPTVAPMKCVVLPLSGNAEFQPFVRDLSQELITVDVSHKVDDSSGSIGRRYARTDELGVPYAVTVDFDTIKEPHTVTLRERDSMRQVRLPMADVPTVVRDLSNSKILWSDVEQKYPKFEQQETVKGTSV
What is the function of this protein?
Catalyzes the ATP-dependent ligation of glycine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (Gly-AMP) (By similarity).  Also produces diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs (By similarity).  Thereby, may play a special role in Ap4A homeostasis (By similarity).  Required for terminal arborization of both dendrites and axons during development (By similarity).
What are the official names of this protein?
Glycine--tRNA ligase, Diadenosine tetraphosphate synthetase, Ap4A synthetase, Glycyl-tRNA synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
[Isoform 1]: Mitochondrion. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. Cell projection, axon.
Protein: SYFB_META3
Sequence: MPTINVNKIDLEKLINMSLSDKTIDHKFPMMGVEVEEIFEENNQKIVQFSINPDRPDYLSVEGLARGFRGFIGIDAGLPKYDIYASDLEVYVENVKSRPYCGFAIIKNIIIDDLVLESIINLQEKLHWSIGRDRKKMAIGIHDLDKIEAPFYYKEINGDEIEFEPLGHNELMTPKEVLEKHEKGVKYAHLLRGDKFPIIVDKNNAVISMPPIINGNLTKVGTETRNLLVEITGTDKNAVENTLNIIVCALADRRGTIFSLKLINNGNETISPDLTPDSAEITIDEINTRLGLNLNAGEIIACLKKARYDAQYSYEDENIKITIPAYRTDILNNMDIIKDVAINYGYENFNGNLPVVATIGEKHDIEKKFEFIRNTMIGYGLFEVMNLTLSNQDVLFNKMNENIEDNEYVEVLKPASIEHRVVRPTILPLLLETLANNKHNELPQKIFEVGDCVVIDEKDETLYTHCKNVPKVSAVITHHNANFNEIKGLVEGLIREMNIEYSIDNYKHPSFIEGRCAKIIVDDEIVGYFGELHPEVILNFELGYPVVGFEMEIK
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y842_HAEIN
Sequence: MKSHVRSFKTYIRDEIIKKGGWVNAHAHADRAFTMTPEKIGIYHSSNLQQKWDLVDEVKRTSSVDDYYARFCQSIELMISQGVTAFGTFVDIDPICEDRAIIAAHKAREVYKHDIILKFANQTLKGVIEPTARKWFDIGAEMVDMIGGLPYRDELDYGRGLEAMDILLDKAKSLGIMCHVHVDQFNNPSEKETEQLCDKTIEHGMEGRVVGIHGISIGSHSKEYRYKLYEKMRKAKMMMIACPMAWIDSNRKEDLMPFHNALTPADEMIPEVSLLP
What are the official names of this protein?
Uncharacterized protein HI_0842.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily.
Protein: PSRP_ACIAC
Sequence: MHTRTVFFISDGTGITAETFGNAILAQFDIKPRHVRLPFIDTEDKAHQAVRRINHTAELEGKKPIVFTTLVNMSVLRIIQENCQGMLLDMFGTFIRPLEGELGIKSLHRVGRFADVSLSKEYTDRIEAINFSLDHDDGQSHRDLSGADVILVGVSRSGKTPTSLYLAMQCGLKVANYPLIPEDFERKQLPPALEPHRKKIFGLTILPERLSQIRNERRPGSKYADLANCRHEVAEAEAMMRRSGIRWLSTTTKSIEEIATTILQEVRPERLVY
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: MER1_EUPRA
Sequence: MNKLAILAIIAMVLFSANAFRFQSRLRSNVEAKTGDACEQAAIQCVESACESLCTEGEDRTGCYMYIYSNCPPYV
What is the function of this protein?
Mating ciliate pheromones (or gamones) are diffusible extracellular communication signals that distinguish different intraspecific classes of cells commonly referred to as 'mating types'.  They prepare the latter for conjugation by changing their cell surface properties.  The membrane-bound form promotes inter-cellular communication and adhesion for mating pair formation and may act as binding site for the secreted form.
What are the official names of this protein?
Mating pheromone Er-1/Er-3, Euplomone R1/R3.
What are the subcellular locations of this protein?
[Isoform 1]: Secreted. SUBCELLULAR LOCATION: [Isoform 2]: Cell membrane.
Protein: HIS6_MICAN
Sequence: MLAKRILPCLDVNKGRVVKGVNFVNLQDAGDPVELARLYNQAGADELVFLDITATHEDRDTIIDVVYRTAEQVFIPLTVGGGIQSLENIKNLLRAGADKVSINSAAVREPELLDRASDRFGKQCIVVAIDARRRKDEHNPGWEVYVRGGRKNTGIDALLWAQEVEKRGAGELLVTSMDADGTQAGYDLALTKAIAERVEIPVIASGGAGNCQHIYEALTEGRAEAALLASLLHYGQLTIAEVKNYLQNQQVPVR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_LEGPH
Sequence: MSGNTFGALFTVTTFGESHGPAIGCVVDGCPPGMSLTEADIQPFLDKRKPGQSKYTTQRREEDKVQILSGVFDGKTTGAPIALLIQNTDQRSRDYEDIKNLFRPGHADFTYHYKYGHRDYRGGGRSSARETAARVAAGAIARLYLKRYLNLDIIGYLQQMGDLKLQFENENEINKNPFFCPNNKQIQELADYVDRLRRQGDSVGARVKILARGVPTGLGDPVFDKLDATLAYAMMSINAVKGVEIGAGFNAVEQLGSHHRDQMTAKGFLSNHAGGILGGIATGQPIEVSIALKPTSSITTPGQTINTEGEEVTVVTKGRHDPCVGIRAVPIAEAMMALVLMDHYLRHKAQCK
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: CLPP_BURCM
Sequence: MITRAELLDMLASNAPQGFEAQALGLVPIVVETSGRGERSYDIYSRLLKERLVFMVGEVNDQTANLVVAQLLFLESENPDKDISLYINSPGGSVSAGMAIYDTMQFIKPDVSTLCMGLAASMGAFLLASGAKGKRFALPNSRVMIHQPLGGARGQASDIEIQAREILYLKERLNNLLAQHTGQDVERIARDTDRDNFMSSEDAKAYGLIDQVLLKRP
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMA_SHELP
Sequence: MAWIQLKIDTDNQHAEQLSDMLMELGSLSITYEDGKDTPIYEPNLGETPLWSHTVITALFEADYDLAPVVEMLKLQPYLGADFSHKIEQVEDKDWEREWMDNFHPIQFGRRLWICPSWREVPDPEAVNVMLDPGLAFGTGTHPTTALCLEWLDGLDLQGKEAIDFGCGSGILAVAALKLGAAKVTGIDIDYQAIDASKANAERNQVADKLDLYLPEDQPADLKAEVLVANILAGPLRELAPLIAEKVQPGGLLALSGLLKEQADEISQHYAQWFDMDAPVHKEDWSRLTGRRK
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CM3G_CONCN
Sequence: MSKLGVLLTICLLLLPLTALPMDEDQPADQPADRMQDDISSEQYPLFDKRQKCCGKGMTCPRYFRDNFICGCC
What is the function of this protein?
Shows a paralytic effect in fish.
What are the official names of this protein?
Conotoxin CnIIIG.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LEUC1_ARCFU
Sequence: MAQTLVEKIFSKASGKEVKAGEFVMANIDLAMIHDITAPLAIKAFREILGSDAKVWDKSKVIMAFDHQVPADSVHAAENHKMLRKFAEEQGILNYDVKGGIAHQIMVENHVEPGMLIVGADSHTCMYGALGAFATGIGSTDMGFVLAMGKLWFKVPESIRFNVHGKLEKHVYGKDIVLKLIGMVGADGANYKACIYSGEVVEKLGMSDRLTMCNMAIEMGGKAGIVEPDKTTLEYLKAMGRPYEGELLKSDEDAEFQEVELDVTGMEPQVAAPHRVDNVVGISEVEGTRVDQVFIGSCTNGRYEDLKIAAEILKGEKVASNVRLIVIPASHREYRRALKEGLIEIFVDAGALVEAPCCGPCMGGSFGLIASGEVSVSTSNRNFIGRQGSPEGKIYLVNPAVAAATAIYGEITDPRKIK
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit 1, Alpha-IPM isomerase 1, IPMI 1, Isopropylmalate isomerase 1.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
Protein: ISPH_GEOSM
Sequence: MQVILAKHAGFCFGVKRATQLAFEAADTGSETYTLGPIIHSPQVVQRLEEMGVIPVEDVSEVETGGTIIIRSHGVAAEELEAAVRANLEVVDATCPFVKKAQEHVATLSKEGYDIVVVGDAVHPEVQGIVSYAAGRVYVVSSDKDVERLPRMSKIGIVAQTTQSFEHLHDVVTACLARGGETRVYNTICDATAVRQDEAKKLAGAVDCMVVIGGFNSANTKRLAQICRELLPRTHHVETACQIDEQWFKGVEKVGVTAGASTPKWIIDEVIDRISAIDKDKIS
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: FOLD_ECO45
Sequence: MAAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSNPASQIYVASKRKACEEVGFVSRSYDLPETTSEAELLELIDALNADNTIDGILVQLPLPAGIDNVKVLERIHPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGLNAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPGDWIKEGAIVIDVGINRLENGKVVGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTLQACVEYHDPQGE
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: DCTA_RHIME
Sequence: MIIEHSAEVRGKTPLYRHLYVQVLAAIAAGILLGHFYPDIGTELKPLGDAFIRLVKMIIAPVIFLTVATGIAGMTDLAKVGRVAGKAMIYFLAFSTLALVVGLVVANVVQPGAGMHIDPASLDAKAVATYAEKAHEQSITGFLMNIIPTTLVGAFAEGDILQVLFISVLFGISLAIVGKKAEPVVDFLQALTLPIFRLVAILMKAAPIGAFGAMAFTIGKYGIASIANLAMLIGTFYLTSFLFVFIVLGAVARYNGFSILSLIRYIKEELLLVLGTSSSEAALPGLMNKMEKAGCKRSVVGLVIPTGYSFNLDGTNIYMTLAALFIAQATDTPLSYGDQILLLLVAMLSSKGAAGITGAGFITLAATLSVVPSVPVAGMALILGIDRFMSECRALTNFVGNAVATIVVAKWEGELDQAQLSAALGGEASVEAIPAVVQPAE
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the inner membrane.  This transport system plays an important role in the energy supply of rhizobium-legume symbionts.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TM145_HUMAN
Sequence: MEPLRAPALRRLLPPLLLLLLSLPPRARAKYVRGNLSSKEDWVFLTRFCFLSDYGRLDFRFRYPEAKCCQNILLYFDDPSQWPAVYKAGDKDCLAKESVIRPENNQVINLTTQYAWSGCQVVSEEGTRYLSCSSGRSFRSGDGLQLEYEMVLTNGKSFWTRHFSADEFGILETDVTFLLIFILIFFLSCYFGYLLKGRQLLHTTYKMFMAAAGVEVLSLLFFCIYWGQYATDGIGNESVKILAKLLFSSSFLIFLLMLILLGKGFTVTRGRISHAGSVKLSVYMTLYTLTHVVLLIYEAEFFDPGQVLYTYESPAGYGLIGLQVAAYVWFCYAVLVSLRHFPEKQPFYVPFFAAYTLWFFAVPVMALIANFGIPKWAREKIVNGIQLGIHLYAHGVFLIMTRPSAANKNFPYHVRTSQIASAGVPGPGGSQSADKAFPQHVYGNVTFISDSVPNFTELFSIPPPATSPLPRAAPDSGLPLFRDLRPPGPLRDL
What are the official names of this protein?
Transmembrane protein 145.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RSSA_DROER
Sequence: MSGGLDILSLKEDDITKMLVATTHLGSENVNFQMEQYVYKRRADGVNILNLGKTWEKLQLAARAIVAIDNPSDIFVISSRPIGQRAVLKFAKYTDTTPIAGRFTPGAFTNQIQPAFREPRLLVVTDPNTDHQPIMEASYVNIPVIAFTNTDSPLRYIDIAIPCNNKSAHSIGLMWWLLAREVLRLRGTISRSVEWPVVVDLFFYRDPEEAEKEEAAAKELLPAPKIEEAVDHPVEETTNWADEVAAETVGGVEDWNEDTVKTSWGSDGQF
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.  Required during oogenesis and imaginal development.
What are the official names of this protein?
40S ribosomal protein SA, Protein stubarista.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=May associate with nascent RNP complexes within the nucleus.
Protein: SBPN1_PINCO
Sequence: MDLISVLPSTSKSCVCLHKPLSSSTHKLKPFCRTIRILGMPRPRKSVLMASSMSMSVNTLVSDDDIQRRTGGYHSNLWNDDVIQFLSTPYGELAYRERGERLIDEVREIFSSMSLEDGEFSDLIQRLWMVDNVERLGIDRHFKNEIKSALDYVYSYWSEKGIGCGTKSIITNLNSTALGFRTLRLHGYPVSADVLKHFRNQIGQFVSCPSETEEDIRSIVNLYRASLIAFPGEKVMEEAERFSEKYLKETLQKIPDCSLSREIGDVLEHGWHTNLPRLEARNYIDVFGQDTKNMESNRKTEKLLELAKLEFNIFQSIQKTELESLLRWWNDSGSPQITFTRHRHVEYYTLASCIAFEPQHSGFRLGFAKACHIITVLDDMYDLFGTVDELKLFTAAIKRWDPSATDCLPQYMKGIYMMVYNTVNEMSAEAQKAQGRDTLNYARQAWEVYLDSYMQEAKWIATGYLPTFEEYLENGKVSSGHRVSALQPMLTMDIPFPPHILKEVDFPSNLNDLACAILRLRGDTRCYQEDRARGEETSCISCYMKDNPGATEEDALNHLNVMISGVIKGLNWELLKPDSGVPISSKKINFDITRAFHYGYKYRDGYSVSSVETKSLVMRTLLEPVPL
What is the function of this protein?
Monoterpene synthase (TPS) involved in the biosynthesis of monoterpene natural products included in conifer oleoresin secretions and volatile emissions; these compounds contribute to biotic and abiotic stress defense against herbivores and pathogens (PubMed:23679205).  Catalyzes the conversion of (2E)-geranyl diphosphate (GPP) to (-)-beta-pinene and, to a lower extent, to (-)-alpha-pinene (PubMed:23679205).
What are the official names of this protein?
(-)-beta-pinene synthase 1, chloroplastic, (-)-alpha-pinene synthase (-)betapin1, chloroplastic, Terpene synthase (-)betapin1, PcTPS-(-)betapin1.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsd subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ENO_SALG2
Sequence: MSKIVKVIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVGAVNGPIAQAILGKDAKDQAGIDKIMIDLDGTENKSNFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKGKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: Y6058_BURP6
Sequence: MNSTPDTFQRPALRELTPLEARVLGVLIEKQHTVPDTYPLSLNALTAGCNQKTARSPVMNVSEAEVLTAIDGLKRLSLASEGSSSRVPRFEHNMNRVLGIPSQAAALLTMLLLRGPQTAAELRLNSARLHGFADISSVEAFLDELAARTPPLVVKLPRAPGARESRWMHLMCGDVAPDEAPAHGAHEDAVPPSEFEALKAEQKALTAELAQLRALVEYMANELGIDVGKLTRGV
What are the official names of this protein?
UPF0502 protein BURPS668_A1958.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.