PharMolix/UniProtQA huggingface dataset:
Protein: IFRD1_RAT
Sequence: MPKNKKRNAPHRGGGGGGGSGAATSAATTGGPHRTVQPFSDEDASIETMSHCSGYSDPSSFAEDGPEVLDEEGTQEDLEYKLKGLIDLTLDKSAKTRQAALEGVKNALSSKVLYEFVLERRMTLTDSIERCLKKGKSDGQRAAAALASVLCIQLGPGLESEEILKTLGPILKKIICDGTASIQARQTCATCFGVCCFIATDDITELYSTLECLEGIFTKSYLKEKDTNVPCSTPNTVLHISSLLAWTLLLTICPISEVKKKLELHFHKLPSLLSCDDVNMRIAAGESLALLFELARGMESDFFYEDMDSLTQMLRALATDGNKHRAKVDKRKQRSVFRDVLRAVEERDFPTETVKFGPERMYIDSWVKKHTYDTFKEALGSGMQYHLQTNEFLRNVFELGPPVMLDAATLKTMKIPRFERHLYNSAAFKARTKARSKCRDKRADVGEFF
What is the function of this protein?
Probably participates in neurogenesis.  Could play a role in regulating gene activity in the proliferative and/or differentiative pathways induced by NGF.
What are the official names of this protein?
Interferon-related developmental regulator 1, IRPR, Nerve growth factor-inducible protein PC4.
What is the protein family that this protein belongs to?
Belongs to the IFRD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Nucleus. Note=Presents a NGF-dependent pattern of intracellular localization. With increasing amounts of NGF and besides being expressed in the cytoplasm, it is also localized in the plasma membrane (inner side) at the onset of NGF-induced differentiation, from where it disappears to reappear in the nuclei of differentiated cells.
Protein: THIG_WIGBR
Sequence: MLKINDTFFKSRLFVGTGKYSSNKIMLESIFASESELITLSIRRMDFNNPQNEFLDTLNRSKIKLLPNTSGAKNAKEAVLAAKIAREALNTNWIKLEIHPETKYLLPDSVETLIAAKILVKDGFVVLPYCFPDPVICHKLVDVGCSAVMPLGSPIGTNLGLINDYFLKIIIEQINIPIIIDAGIGSPSHAVKAIEIGADAVLVNTAIATSNNPVKMAKSFKIALQAAEIAKNSGLSGKSFISHRSSPLTDFLNY
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_ANOFW
Sequence: MLMPKRVKYRREHRGRMKGRAKGGTEVHFGEYGLQALEPAWITNRQIEAARRAMTRYMRRGGKVWIKIFPSKPYTAKPLEVRMGSGKGAPEGWVAVVKPGKVMFEIAGVSEEVAREALRLASHKLPIKCKFVKREEIGGESNES
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: TYSY_THIDA
Sequence: MKPYLDLMRHVLEHGTRKDDRTGTGTLSVFGWQTRYDLAAGFPLVTTKKCHLRSIVHELLWFLQGDTNIRYLKENGVSIWDEWADENGDLGPVYGHQWRSWPKADGGVIDQIAEAVKTLRTNPDSRRIIVSAWNVADLDRMALAPCHAFFQFYVAEGRLSCQLYQRSADIFLGVPFNIASYALLTLMMAQVTGLKPGDFVHTLGDAHLYVNHLEQAREQLSREPRPLPTMTLNPDVTDIFGFRFEDFTLGGYDPHPAIKAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGA_CALS8
Sequence: MNVLFAVSEAFPFAKTGGLADVAYSLPKALRKLGVDIRVIMPKYGDIPSDYTTKMKHLCHFTVPVGWRNQYCGIEYLNFEGVPFYFIDNEYYFKRPGYYGYYDDGERFSYFSRAVCEAIYHLDFDVDIIHVNDWHTSVIPVLLKAHYSHSPKHQKIKTVLTIHNLRYQGVFPKEVMYDLLSLPDEYFDENKLKFYDAISFLKGGIIFADKVVTVSKTYANEIRTLSHGEGLHGLLSGIGEKLVGIVNGIDYEVCNPATDKLIFVNYDANTFESRKKENKFRLQQMLNLPVSDDIVLIGMVSRLTKEKGIDLIERILSRLLTLPVQLVILGAGDYHYEQMFKYYAIAYPSKVSANICYSEELARKIYAGSDIYLMPSLTEPCGISQLIAMRYGTVPIVRETGGLKDTVKPYNQFTGEGWGFSFANYDPAELFAIIKYALSIYSDKAQWRSIVHQAMTRDNSWNASAGEYNRVYEQLLK
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: BBS12_MOUSE
Sequence: MEMACRVINRRRHVGLQQLLSFAQTGRSFLGPVKATKFITDAECHESVLISSTVRLLEGLDLTCAVGHLLNEAVQAQNNTYKIGTSTLLFLVGAWSRAVEDCLHLGIPTTVIVSVMSEGLNSCIEAVVSLQVPIHNVFDHMDNTSTVYKLETVNATLCPFLQDPSGSGLLQEKRDFKDATSPLLSTYSLSGRHAESPKFFKPQNNLETEKNTLQVLKNNLYTDSFCKKSALAHSRHFNRTDNSHWISRHDGFLEQLESTPKVLRCNDFGELAVGLSHGDHSSMALAKAAVRLQWQSLCLQQANWMAPFMFDISRLLTCCIPGLPETFSRVGLGYVTFVTMSSITLIKELQDQPFRVILIEGDLTESYRHLGFNKSVNIKTKLDSGELSEDSAEELWTNHVLQVLIQFNVTLILVQGSVSEHLTEKCMHSKRLVIGAVNGSVLQAFAEATRAVPVAYVTQVNEDCVGSGVSVTFWMSPHDINRSNRIAILLTAEGINLITAVLTSPASAQMETKEDRFWSCVYRLYHALKEEKVFLGGGAVEFLCLSHLQILAEQSLNRGNHACLGWLPDSSSWMASSLSVYRPTVLKSLAGGWHEFLSAIMCNTATHPSAVEARTFIQQHVQNAIDSGSPSSYILSEYSKLSSGVFHSGISDNLELVPRVYDTVTPKIEAWRRALDVVLLVLQTDSEIITGLVHTEMNSQELDGVLFL
What is the function of this protein?
Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis.  As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia.  Involved in adipogenic differentiation.
What are the official names of this protein?
Bardet-Biedl syndrome 12 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family. BBS12 subfamily.
What are the subcellular locations of this protein?
Cell projection, cilium. Note=Located within the basal body of the primary cilium of differentiating preadipocytes.
Protein: RA54B_HUMAN
Sequence: MRRSAAPSQLQGNSFKKPKFIPPGRSNPGLNEEITKLNPDIKLFEGVAINNTFLPSQNDLRICSLNLPSEESTREINNRDNCSGKYCFEAPTLATLDPPHTVHSAPKEVAVSKEQEEKSDSLVKYFSVVWCKPSKKKHKKWEGDAVLIVKGKSFILKNLEGKDIGRGIGYKFKELEKIEEGQTLMICGKEIEVMGVISPDDFSSGRCFQLGGGSTAISHSSQVARKCFSNPFKSVCKPSSKENRQNDFQNCKPRHDPYTPNSLVMPRPDKNHQWVFNKNCFPLVDVVIDPYLVYHLRPHQKEGIIFLYECVMGMRMNGRCGAILADEMGLGKTLQCISLIWTLQCQGPYGGKPVIKKTLIVTPGSLVNNWKKEFQKWLGSERIKIFTVDQDHKVEEFIKSIFYSVLIISYEMLLRSLDQIKNIKFDLLICDEGHRLKNSAIKTTTALISLSCEKRIILTGTPIQNDLQEFFALIDFVNPGILGSLSSYRKIYEEPIILSREPSASEEEKELGERRAAELTCLTGLFILRRTQEIINKYLPPKIENVVFCRPGALQIELYRKLLNSQVVRFCLQGLLENSPHLICIGALKKLCNHPCLLFNSIKEKECSSTCDKNEEKSLYKGLLSVFPADYNPLLFTEKESGKLQVLSKLLAVIHELRPTEKVVLVSNYTQTLNILQEVCKRHGYAYTRLDGQTPISQRQQIVDGFNSQHSSFFIFLLSSKAGGVGLNLIGGSHLILYDIDWNPATDIQAMSRVWRDGQKYPVHIYRLLTTGTIEEKIYQRQISKQGLCGAVVDLTKTSEHIQFSVEELKNLFTLHESSDCVTHDLLDCECTGEEVHTGDSLEKFIVSRDCQLGPHHQKSNSLKPLSMSQLKQWKHFSGDHLNLTDPFLERITENVSFIFQNITTQATGT
What is the function of this protein?
Involved in DNA repair and mitotic recombination.  May play an active role in recombination processes in concert with other members of the RAD52 epistasis group.
What are the official names of this protein?
DNA repair and recombination protein RAD54B, RAD54 homolog B.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RSMH_MYCPN
Sequence: MLSNQPHKSVLLDEVIHNLNIKGDGNYLDLTVGFGGHSQHILEQLTTGTLTGNDMDKDSITFCTELFKDKKNVVLVHDNFANFFNHLKQLKVTKFDGILIDLGVSSYQLDKPERGFSFKHAGPFDMRMHQSDRVPTALDILERLSEEELTHVLKKFGEIAHPKPIAKALKTLINNTKNPTTVEVAETVKAAASNFEKYKSRNYLAKVFQAIRIYLNRELESLEIVLQHIPKLLNNKGRFLVIVFHSLEEKLVRNYIFKLTHFVQPPELPVKLTPPFELITKKPILPTEQEIKTNPRVRSAKLFVIEKK
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADD_NITSB
Sequence: MKIAIFGGSFDPPHKGHIAIVKRALEELDIDYVIIVPTYLNPFKTSFQASPSLRLRWLRKIFLPYNRVKICDYEVRKGRPTYAIETVEFLRRKYAPKKLYYIIGSDNLPTLHKWHKYQKLSHLVQFVVATRKGYKVPKKYKMIEVHEDISSTELRIHPKKRYLPPIVAEEIIRFYRS
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: ECM29_MOUSE
Sequence: METGSDSDQLERVFLRLGHAETDEQLQNIISKFLPPVLLKLSSTQEGVRKKVMELLVHLNKRIKSRPKIQLPVETLLVQYQDPAAVSFVTNFTIIYVKMGYPRLPVEKQCELAPTLLTAMEGKPQPQQDSLMHLLIPTLFHMKYPAESSKSASPFNLAEKPKTVQLLLDFMLDVLLMPYGYVLNESQSRQNSSSSSQGSSSNSGGGSGIPQPPPGMSFYAAKRVIGDNPWTPEQLEQCKLGIVKFIEAEQVPELEAVLHLVIASSDTRHSVATAADLELKSKQSLIDWNNPAIINKMYKVYLGDIPLKTKEGAVLKPELKRDPVSTRVKLKIVPHLLRSRQAAETFPANIQVVYDGLFGTNTNSKLRTLSLQFVHHICLTCPEIKIKPLGPMLLNGLTKLINEYKEDPKLLSMAYSAVGKLSSRMPHLFTKDIALVQQLFEALCKEEPETRLAIQEALSMMVGAYSTLEGAQRTLMEALVASYLIKPEVQVRQVAVKFASTVFPSDHIPSRYLLLLAAGDPREEVHGEAQRVLRCLPGRNKKESASKQMPSFPEMVYYIQEKASHRMKTPVKYMTGTTVLPFNPAAFGEIVLYLRMCLAHSAGVVPTSQSLADMQDHAPAIGRYIRALMSSSQATASSSNKSGETNPVQIYTGLLQQLLAGVGGLPVMYCLLEAVSVYPEKLATKFVDKTEWIKSLMSSSKEEMRELAALFYSVVVSTVSGIELKSMIEQLIKATKDNHSPEVQHGSLLALGFTVGRYLAKKRVRMAEQHDLETDADLLPEQEEIIRSATETIGSFLDSTSPLLAIAACTALGEIGRNGPLPIPSEGSGFTKLHLVESLLNRIPSSKETNKMKERAIQTLGYFPVGDGVFPHQKLLLQGLMDSVEAKQIELQFTIGEAITSAAIGTNSVAARDAWLVTEEEYIPPAGAKVNDVVPWVLDVILNKHIISPNPHVRQAACIWLLSLVRKLSTHREVKSHLKEIQSAFVSVLSENDELSQDVASKGLGLVYELGNEQDQQELVSTLVETLMTGKRVKHEVSGETVVFQGGGLGKTPDGQGLSTYKELCSLASDLSQPDLVYKFMNLANHHAMWNSRKGAAFGFNVIATRAGEQLAPFLPQLVPRLYRYQFDPNLGIRQAMTSIWNALVTDKSMVDKYLKEILQDLIKNLTSNMWRVRESSCLALNDLLRGRPLDDVIDKLPEMWETLFRVQDDIKESVRKAAELALKTLSKVCVKMCDPAKGAAGQRTIAVLLPCLLDKGMMSPVTEVRALSINTLVKISKSAGAMLKPHAPKLIPALLESLSVLEPQVLNYLSLRATEQEKDVMDSARLSAAKSSPMMETINMCLQYLDVSVLGELVPRLCELIRSGVGLGTKGGCASVIVSLTTQCPQDLTPYSGKLMSALLSGLTDRNSVIQKSCAFAMGHLVRTSRDSSTEKLLQKLNGWYMEKDEPVYKTSCALTIHAIGRYSPDVLKNHAKEVLPLAFLGMHEIADEEKSEKEECNMWTEVWQENVPGSFGGIRLYLQELITITQKALQSQSWKMKAQGAIAMASISKQTSSLVPPYLGMILSALMQGLAGRTWAGKEELLKAIACVVTACSTELEKSVPNQPTTNEILQAVLKECCKENLKYKIVAISCAADVLKATKEDRFQEFSDIVIPLIKKNSLESMGVRTTKAEDENEKERELQLESLLGAFESLGKAWPRNPDTQRCYRQELCKLMCERLRLSTWKVQLGVLQSMNAFFQGLMLLEEEHADPEALAEILLETCKSITYSLENKTYSSVRTEALSVVELLLKKLEEAKQWESLTAECRGLLIESLATMETDNRPELQEKASVLKKTLESLE
What is the function of this protein?
Adapter/scaffolding protein that binds to the 26S proteasome, motor proteins and other compartment specific proteins.  May couple the proteasome to different compartments including endosome, endoplasmic reticulum and centrosome.  May play a role in ERAD and other enhanced proteolysis (By similarity).  Promotes proteasome dissociation under oxidative stress (PubMed:26802743).
What are the official names of this protein?
Proteasome adapter and scaffold protein ECM29, Proteasome-associated protein ECM29 homolog.
What is the protein family that this protein belongs to?
Belongs to the ECM29 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Endoplasmic reticulum-Golgi intermediate compartment. Endosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Endosome, multivesicular body. Cytoplasmic vesicle.
Protein: RL18_THESM
Sequence: MAHGPRYRVPFRRRREGKTNYHKRLALLKSGKPRLVVRKTLNHHVAQIVLYAPEGDKTVVSAHTRELMRDFGWKGHGGNTPSAYLLGLLIGYKALEKGIEEAILDIGLHPPTKGSSIFAVLKGAVDAGLNVPHSEEIYPGEERINGKHIAEYAKMLKEDDENYKKQFGGYLVKGLEPEKLPEHFEEVKARIIEKFEKVRA
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: GCST_NITEC
Sequence: MLKTTPLNAAHRGMHAKMVDFGGWDMPLHYGSQLDEHHAVRRDAGMFDVSHMLTVDLHGENVRQFLRGLVANNIDKLTVPGKALYTCMLNPAGGIIDDLIIYFLSESWFRLVVNAGTADKDIDWITLQSSQHAPDLTITPRRDLAMIAVQGPNARAKVWAVIPDSKAASEDLKPFQSVAFGNYFIARTGYTGEDGFEITLPADEAAAFWQKLHAAGVAPAGLGSRDTLRLEAGMNLYGQDMDETTNPLESGLAWTVDLKSERDFIGKQALLEKPVNQQLVGLVLLDKGVLRNHQKIITQHEGIAGEGEITSGGFSPTLNQSIALARIPVGIAAGEQVHVVVRDKQLAARVVKYPFVRNGQALI
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: PAND_RUTMC
Sequence: MKRTFLSAKLHKVITTAVELDYEGSCEIDGVLLDAADIGAFEQIQIYNINNGNRFTTYTIRGKDNSGVISVNGAAAHKVNVGDMLIIAAYGVYSEKELESYTPRLCYVNDQNILTKISS
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNME_STAAC
Sequence: MDLDTITSISTPMGEGAIGIVRLSGPQAVEIADKLYKGKHLLNDVPSHTINYGHIIDPESKEVIEEVMVSVLRAPKTFTREDIIEINCHGGILTINRVLELTMTYGARMAEPGEFTKRAFLNGRIDLSQAEAVMDFIRSKTDRASKVAMNQIEGRLSDLIKKQRQSILEILAQVEVNIDYPEYDDVEDATTEFLLEQSKEIKQEINRLLDTGAQGKIMREGLSTVIVGKPNVGKSSMLNNLIQDNKAIVTEVAGTTRDVLEEYVNVRGVPLRLVDTAGIRETEDIVEKIGVERSRKALSQADLILFVLNNNEALTQEDYTLYEVVKNEDVIVIVNKMDLEQNIDINEVKDMIGDTPLIQTSMLKQEGIDELEIQIRDLFFGGEVQNQDMTYVSNSRHISLLKQARQTIQDAIDAAESGVPMDMVQIDLTRTWEILGEIIGETASDELIDQLFSQFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BRLA_PENCA
Sequence: MRSHGQQISDRLTVEVDCHSLGPSECPSMTSSFSPLDSPTPTPTSLYSQGSMASPGWHEHPHYHHGVPMERRTSATPLRSAFRMADITSGDAMMNMPCGNMDRQDQMALPDYLPAYEENVDQLWIPQDMPKTYQEPQFPYHASMSQYNQMARNYYHRPQQAGYLPESASNPCLSRPIFTQPTERMPNSASMTNMLHWMPSHESLVPQTITPAQVQPFPSGPVTPPSSSYSDFPTNIPTFKSHTPSTPHRSVSMGTPSGSDTPVSRMSGHNDYQEEFQLSPVYREGMMQRHRQPSRKSSKKQLLRSNLSLENLPSIIKQVQFKCKEPGCKGRFKRQEHLKRHMKSHSKEKPHVCWVPGCHRAFSRSDNLNAHYTKTHSKRGGRNRYVATLDETSQDFDPDFRGQLTPDGRPIYGSKLEDSMPDCGELSVDGWDD
What is the function of this protein?
BrlA, abaA and wetA are pivotal regulators of conidiophore development and conidium maturation (By similarity).  They act individually and together to regulate their own expression and that of numerous other sporulation-specific genes (By similarity).  Binds promoters of target genes at brlA response elements (BREs) containing the conserved sequence 5'-(C/A)(A/G)AGGG(G/A)-3' (By similarity).
What are the official names of this protein?
C2H2 type master regulator of conidiophore development brlA.
What are the subcellular locations of this protein?
Nucleus.
Protein: OPGB_ECO81
Sequence: MSELLSFALFLASVLIYAWKAGRNTWWFAATLTVLGLFVVLNITLFASDYFTGDGINDAVLYTLTNSLTGAGVSKYILPGIGIVLGLAAVFGALGWILRRRRHHPHHFGYSLLALLLALGSVDASPAFRQITELVKSQSRDGDPDFAAYYKEPSRTIPDPKLNLVYIYGESLERTYFDNEAFPDLTPELGALKNEGLDFSHTQQLPGTDYTIAGMVASQCGIPLFAPFEGNASASVSSFFPQNICLGDILKNSGYQNYFVQGANLRFAGKDVFLKSHGFDHLYGSEELKSVVADPHYRNDWGFYDDTVLDEAWKKFEELSRSGQRFSLFTLTVDTHHPDGFISRTCNRKKYDFDGKPNQSFSAVSCSQENIATFINKIKASPWFKDTVIVVSSDHLAMNNTAWKYLNKQDRNNLFFVIRGDKPQQETLAVKRNTMDNGATVLDILGGDNYLGLGRSSLSGQSMSEIFLNIKEKTLAWKPDIIRLWKFPKEMKEFTIDQQKNMIAFSGSHFRLPLLLRVSDKRVEPLPESEYSAPLRFQLADFAPRDNFVWVDRCYKMAQLWAPELALSTDWCVSQGQLGGQQIVQHVDKAIWKGKTAFKDTVIDMARYKGNVDTLKIVDNDIRYKADSFIFNVAGAPEEVKQFSGISRPESWGRWSNAQLGDEVKIEYKHPLPKKFDLVITAKAYGNNASRPIPVRVGNEEQTLVLGNEVTTTTLHFDNPTDADTLVIVPPEPVSTNEGNILGHSPRKLGIGMVEIKVVEREG
What is the function of this protein?
Transfers a phosphoglycerol residue from phosphatidylglycerol to the membrane-bound nascent glucan backbones.
What are the official names of this protein?
Phosphoglycerol transferase I, Phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the OpgB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CAT2_HAEIF
Sequence: MNFTRIDLNTWNRREHFALYRQQIKCGFSLTTKLDITAFRTALAETDYKFYPVMIYLISRVVNQFPEFRMAMKDNALIYWDQTDPVFTVFHKETETFSALFCRYCPDISEFMAGYNAVMAEYQHNTALFPQGALPENHLNISSLPWVSFDGFNLNITGNDDYFAPVFTMAKFQQEDNRVLLPVSVQVHHAVCDGFHAARFINTLQMMCDNILK
What is the function of this protein?
This enzyme is an effector of chloramphenicol resistance in bacteria.
What are the official names of this protein?
Chloramphenicol acetyltransferase 2, Chloramphenicol acetyltransferase II, CAT-II.
What is the protein family that this protein belongs to?
Belongs to the chloramphenicol acetyltransferase family.
Protein: GLPK_RHIME
Sequence: MGGYILAIDQGTTSTRAIVFDGNQKIAGVGQKEFKQHFPKSGWVEHDPEEIWQTVVSTVKEAIEKSGITANDIAAIGITNQRETVVVWDRETGKPIHNAIVWQDRRTAAFCDKLKKKGLEKTFVKKTGLLLDPYFSGTKLNWLLSNVKGAQVRAAKGELCFGTIDTFLIWRLTGGECFCTDATNASRTLLYNIAENAWDDELTEVLRVPKEMLPEVKDCAADFGVTDPSLFGAAIPILGVAGDQQAATIGQACFKPGMLKSTYGTGCFALLNTGKDMVRSKNRLLTTIAYRLDGETTYALEGSIFVAGAAVQWLRDGLKVIKAAPDTGSLAESADPSQEVYLVPAFTGLGAPHWDPDARGAIFGMTRNTGPAEFARAALEAVCYQTRDLLEAMHKDWRRNGNDTVLRVDGGMVASDWTMQRLSDLLDAPVDRPVILETTALGVAWLAGSRAGVWPNQEAFAKSWARDRRFEPHMDEATRKVKLKGWRSAVKRTLIAA
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: RTN2_XENTR
Sequence: MGHVLSFTHCKDAPSTASSTPDSCPPEGEEDDSPVTEVNFWPLPSPHEPTFSYITIGSTAPLSRPPVRARRGLGQSRVHAAPREETEEKEVKDVVTYVLLEKTCQLKKLSPPHVQEEVVFVAKPQPQLEVFRAVKDLLYWRDILLSAGCLTGVTLSLLCLSQFSVISVFAYGCLIILSVTLTLRLYTKLLHALKRGNGANPFQYYLDADLKLTTKQAEEITARVLSLLSTTICTLRSLFLVEELKDSLKFLVIIYLLTYVGAVFNGITVLLLCVIGAFTFPILYKQHQTQVDHYVSLVSKKGNAFRSKIQGTVKKPPAKQK
What is the function of this protein?
Inhibits amyloid precursor protein processing, probably by blocking BACE1 activity (By similarity).  Enhances trafficking of the glutamate transporter SLC1A1/EAAC1 from the endoplasmic reticulum to the cell surface (By similarity).  Plays a role in the translocation of SLC2A4/GLUT4 from intracellular membranes to the cell membrane which facilitates the uptake of glucose into the cell (By similarity).
What are the official names of this protein?
Reticulon-2.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Sarcoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cell membrane, sarcolemma; Multi-pass membrane protein. Cell membrane, sarcolemma, T-tubule; Multi-pass membrane protein. Cytoplasm, myofibril, sarcomere, Z line. Cytoplasm, cytoskeleton.
Protein: PURNU_AQUAE
Sequence: MYKQDFPEGKEALNLEIRLGNKLVRFRKFTGKEKIYLPIQRHTDKVIKLIDKDSPPLEGDAVITNLKNVEIGVRTADCVPIILLGKEWVGAVHAGWRGLKKGIIAKTLKALKEEGEDDITALVFPSAKGCCYEVGKEFKEFFRRNLKERNGKLFFDPQREAVEQLRENGIKSILVWEKCTICSPELPSYRRDKTKERMLTSVVILF
What is the function of this protein?
Purine nucleoside enzyme that catalyzes the phosphorolysis of adenosine and inosine nucleosides, yielding D-ribose 1-phosphate and the respective free bases, adenine and hypoxanthine.  Also catalyzes the phosphorolysis of S-methyl-5'-thioadenosine into adenine and S-methyl-5-thio-alpha-D-ribose 1-phosphate.  Also has adenosine deaminase activity.
What are the official names of this protein?
Purine nucleoside phosphorylase aq_167, Adenosine deaminase aq_167, S-methyl-5'-thioadenosine phosphorylase aq_167.
What is the protein family that this protein belongs to?
Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.
Protein: Y4187_BRUSU
Sequence: MKPKISFNNVVMRYGGFLALDRLNLDIADGEFVTVVGPSGCGKSTAMNIAAGLLQPSGGEILVGDKPVTGPGPERGVIFQQYALFPWLTVRQNVEFGLSVAGMSRVKRREISDHYLSLVGLTDFADALPKALSGGMKQRCAIARAYAAAPEILLMDEPFGALDALTRVHMQDQLLDAWSRERRTVMFITHDVDEAVYLANRVIVMAARPGRLDQIIPVDLPYPRTEAIRLSPEFAAIRNRVWHAVYHQQPQTDQQSSHGQ
What is the function of this protein?
Probably part of an ABC transporter complex.  Probably Responsible for energy coupling to the transport system (Probable).
What are the official names of this protein?
Putative ATP-binding protein BRA1187/BS1330_II1178.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SPDLY_MACFA
Sequence: METDIVINLRCKLKEAEEERLKAAQYGLQLVESQNELQNQLDKCRNEMMTMTESYEQEKYTLQREVELKSRMLESLSCECEAIKQQQKMHLEKLEEQLSRSHGQEVNELKSKIEKLKVELDEARLSEKQLKHQVDHQKELLSCKSEELRVMSERVQESMSSEMLALQIELTEMESMKTTLKEEVNELQYRQEQLELLITNLMRQVDRLKEEKEEREKEAVSYYNALEKARVANQDLQVQLDQALQQALDPNSKGNSLFAEVEDRRAAMERQLISMKVKYQSLKKQNVFNREQMQRMKLQIATLLQMKGSQTEFEQQERLLAMLEQKNGEIKHLLGEIRNLEKFKNLYESMESKPSVDSGALEDNTYYTDLLQMKLDNLNKEIESTKGELSIQRMKALFESQRALDIERKLFANERCLQLSESENMKLRAKLDELKLKYEPEETVEVPVLKKRREVLPVDITTSKDTCVNNSAVGGEVYRLPPQKEETQCCPNSLEDNNLQLEKSVSIHTPIVSLSPHKNLPVDMQLKKEKKCVKLVGVPADAEALSERSGNTLNSPRLAAESKLQTEVKEGKETASKLEKETCKKSHPILYVSSKSTPETQCPQQ
What is the function of this protein?
Required for the localization of dynein and dynactin to the mitotic kintochore.  Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex.  Also required for correct spindle orientation.  Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment.  Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin.  Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track) (By similarity).  Plays a role in cell migration (By similarity).
What are the official names of this protein?
Protein Spindly, Coiled-coil domain-containing protein 99, Spindle apparatus coiled-coil domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the Spindly family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore. Nucleus. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes to the nucleus in interphase and to the kinetochore in early prometaphase. Relocalizes to the mitotic spindle pole before metaphase and is subsequently lost from the spindle poles after chromosome congression is completed. Removal of this protein from the kinetochore requires the dynein/dynactin complex.
Protein: YACG_SALNS
Sequence: MSDVTVVNCPTCGKPVVWGEISPFRPFCSKRCQLIDLGEWAAEEKRIASSGDQSDSDDWSEER
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.