PharMolix/UniProtQA huggingface dataset:
Protein: TGBR3_HUMAN
Sequence: MTSHYVIAIFALMSSCLATAGPEPGALCELSPVSASHPVQALMESFTVLSGCASRGTTGLPQEVHVLNLRTAGQGPGQLQREVTLHLNPISSVHIHHKSVVFLLNSPHPLVWHLKTERLATGVSRLFLVSEGSVVQFSSANFSLTAETEERNFPHGNEHLLNWARKEYGAVTSFTELKIARNIYIKVGEDQVFPPKCNIGKNFLSLNYLAEYLQPKAAEGCVMSSQPQNEEVHIIELITPNSNPYSAFQVDITIDIRPSQEDLEVVKNLILILKCKKSVNWVIKSFDVKGSLKIIAPNSIGFGKESERSMTMTKSIRDDIPSTQGNLVKWALDNGYSPITSYTMAPVANRFHLRLENNAEEMGDEEVHTIPPELRILLDPGALPALQNPPIRGGEGQNGGLPFPFPDISRRVWNEEGEDGLPRPKDPVIPSIQLFPGLREPEEVQGSVDIALSVKCDNEKMIVAVEKDSFQASGYSGMDVTLLDPTCKAKMNGTHFVLESPLNGCGTRPRWSALDGVVYYNSIVIQVPALGDSSGWPDGYEDLESGDNGFPGDMDEGDASLFTRPEIVVFNCSLQQVRNPSSFQEQPHGNITFNMELYNTDLFLVPSQGVFSVPENGHVYVEVSVTKAEQELGFAIQTCFISPYSNPDRMSHYTIIENICPKDESVKFYSPKRVHFPIPQADMDKKRFSFVFKPVFNTSLLFLQCELTLCTKMEKHPQKLPKCVPPDEACTSLDASIIWAMMQNKKTFTKPLAVIHHEAESKEKGPSMKEPNPISPPIFHGLDTLTVMGIAFAAFVIGALLTGALWYIYSHTGETAGRQQVPTSPPASENSSAAHSIGSTQSTPCSSSSTA
What is the function of this protein?
Binds to TGF-beta.  Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors.
What are the official names of this protein?
Transforming growth factor beta receptor type 3, TGF-beta receptor type 3, TGFR-3, Betaglycan, Transforming growth factor beta receptor III, TGF-beta receptor type III.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Cell membrane; Single-pass type I membrane protein. Note=Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix.
Protein: LIPA_GEOKA
Sequence: MATKEEHVRKPDWLKIKLNTNENYIGLKKLMRENRLHTVCEEAKCPNIHECWAVRRTATFMILGSVCTRACRFCAVKTGLPTELDWQEPERVAESVRIMNLKHVVVTAVARDDLKDGGAAVFAETVRAIRRKNPFTTIEVLPSDMGGVYENLKILMDARPDILNHNIETVRRLTPRVRARATYERSLEFLRRAKELQPDIPTKSSIMVGLGETKEEIIEAMDDLRANHVDILTIGQYLQPTKKHLKVVKYYHPDEFQELKEIALSKGFSHCEAGPLVRSSYHADEQVSEAAKARQLKA
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YC64_SCHPO
Sequence: MDLSFIEGFETIWTVVRAVVLNYLLRSLKILSTILYVSAVISWNVSLKVFGNVLLPGFLTIRTVVIFILRIVSLFLWILADPAILLVQSVYWYFIRAPARFILMVGITLYPLYVLLSWAVFLGIIVGFSLNSVFTFIDSFATPSSNSTVTEAMTKMKNEKVLEYPYKDRNIMLGDLASRIPSKDSEKLDEERQPIALEKTKSLDSISHSSSSSRKSSTELKIPPVETRIVAEIPVPSSVKRRRHRPNKSMGSIKNS
What are the official names of this protein?
Uncharacterized membrane protein C1919.04.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus membrane; Multi-pass membrane protein.
Protein: GLNA_NEUCR
Sequence: MASESTILSNAENLKKFLRLPQNGQLIAEYIWIDSEGGTRSKSRTLPEKESQYLPEELPIWNFDGSSTGQAPGENSDVYLKPVAVFPDPFRGSPNILVLSECWNADGTPNKFNHRHEAAKLMEAHADQVPWFGLEQEYTLLDINDRPYGWPRNGFPAPQGPYYCGVGTGKVVQRDIVEAHYKCCLYAGVKISGTNAEVMPAQWEFQVGPCDGIEMGDHLWLARFLLHRVSEEFGAKVSFDPKPIPGDWNGAGLHTNFSTENMRKEGGMKYIEDAIKKLEARHKEHIAVYGEGNDKRLTGRHETGSIDSFTYGVANRGASIRIPRECGAKGYGYFEDRRPASNADPYQITGIIMETCFGAVSE
What are the official names of this protein?
Glutamine synthetase, GS, Glutamate--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA_FRATO
Sequence: MENKSNSQILFAEAQQYIPGGVNSPVRAFKSVGQEFPRFIKFAKGAYLYDVDWNKYIDYIGSWGPMILGHCDDDVLEAIQCQVKNGLSYGAPCKQEVDLAKKIIELMPNIEQVRFVNSGTEATISAIRLARAYTCRNKIIKFEGCYHGHADEFLVAAGSGALSLGQPNSPGVPEDVVKDTLVASFNDMESIQALFEKYKDEIACIIVEPIAGNMNMIFPQDGFLAKLRAICDQNSSLLIFDEVMTGFRVALGGAQSIYNVKPDLTTLGKVIGGGMPVGAFGGRKEIMQKVSPAGPVYQAGTLSGNPIAMTAGIKTLEKISQPGFFDELGAKAQKLVDGLNEAAKAYDFNFHAKCLGGMFGLFFCSDKIAVNTFVDLGKTNLKMFNQFFAYMLDNGVYLAPSAYEAGFISIAHSDEDIEKTICLAKKFFQEN
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ESPG5_MYCMM
Sequence: MDQQSTRTDITVNVDGFWMLQALLDIRHVAPELRCRPYVSTDSNDWLNEHPGMAVMREQGIVVGDTVNEQVAARMRVLAAPDLEVVALLSRGKLLYGVVDNEDQPPGSRDIPDNEFRVVLARRGQHWVSAVRVGNDITVDDVSVSDSASIAALVIDGLESIHHADPAAINAVNVPLEEMLEATKSWQESGFNVFSGGDLRRMGISASTVAALGQALSDPAAEVAVYARQYRDDAKGPSASVLSLKDGSGGRIALYQQARTAGSGEAWLAICPATPQLVQVGVKTVLDTLPYGEWKTHSRV
What is the function of this protein?
Specific chaperone for cognate PE/PPE proteins.  Plays an important role in preventing aggregation of PE/PPE dimers.  Required for LipY and PE31/PPE18 secretion.
What are the official names of this protein?
ESX-5 secretion-associated protein EspG5.
What is the protein family that this protein belongs to?
Belongs to the EspG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_RHIEC
Sequence: MTDLRHYDVIVSPAITEKSTLVSENNQVVFNVAKQATKPEIKAAVEALFGVKVTAVNTLLRKGKTKRFRGFVGKQKDVKKAVVTLAEGQTIDVSTGL
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: TADA_STRPQ
Sequence: MPYSLEEQTYFMQEALKEAEKSLQKAEIPIGCVIVKDGEIIGRGHNAREESNQAIMHAEMMAINEANAHEGNWRLLDTTLFVTIEPCVMCSGAIGLARIPHVIYGASNQKFGGADSLYQILTDERLNHRVQVERGLLAADCANIMQTFFRQGRERKKIAKHLIKEQSDPFD
What is the function of this protein?
Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
What are the official names of this protein?
tRNA-specific adenosine deaminase.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: Y6027_FRAAA
Sequence: MATTSRRPVLTRAKVIVPVLLAVALVIAFVAIFTRLYTDLLFYRSVDFSKVFTTVIYTRILLFLIFGAVMAVVIGTNIVLGYRFRPQLRPLSTEQQNLERYRSAIEPYMKLVLVAVAAVFGLAAGLSASGRWRTWLLWVNGESFGTKDPQFHRDISYYAFTYPFQRFLLGFLLTAVLLSLLVTVLTHYLFGGIRLQTPGERVTPAAKAHISVLLGLLALLKAWAYYLDRFGSVFSSRGVATGASYTDVHAVLPAKLILLFISLACAVLFIYNIFQRGWTLPLLGAGILVLSSVVIGGIYPAFIQQFQVRPNEATREQPYIERNIAATRAAYGIQNVKPQSYAARTDVTAAQVAADTGTVPNTRLLDPSKLSRTFQQLQQIRGYYTFPKTLDVDRYTVTGADKKQTTRDYVVSVRELNQAGLGADQRNWINEHLTYTHGKGFVAAPSNTVDEGQPAFDEGEQNLPQKGDFDVRENRVYFGEMSPNYSVVGTRQVEIDGPGPGADTQVTTTYTGDGGVSIGSTFRQALFALRFGEKNLLLSGDITKNSRILYERNPRDRVSKAAPWLTLDGDPYPAVVNGRITWILDGYTTSDGYPYSARRTLGDVTADSVTAQSGNRARQAANQVNYIRNSVKATVDAYDGTVTLYAWDESDPVLRTWMKAFPDTVKPKKDISPSLMAHLRYPEDLFKVQRDLIGQYHVSDPRDFYSQEDFWQVSESPDGSGQPQPPFYVYSKLPDRSGPSYNLTSPLISARSSKLAAYMAVSSDPSNYGQFTLLKLPPGGTINGPVQVQNAIESNGDVANKLTLWRGAGSQTIEGNLLTLPVAGGLLYVEPYYVQARGGSGYPTLQGIATAFGERIGFGTSLGEALDKVFGSGAGAAAAGAGTGATTTTGGGGQATTQGGGTGAAPPGGTSGLQDAVNDADSAYKAGQDALRKNPPDFNAYGQAQTDLADALSRLRTLASPPTTPPAASPTPSRSAAPTTRGTAAGSAPPGTTPAVAAPAGPSGPPSPAGATAGPPQQPRAAPPPG
What are the official names of this protein?
UPF0182 protein FRAAL6027.
What is the protein family that this protein belongs to?
Belongs to the UPF0182 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRUA_ONYPE
Sequence: MQHFFYKLILSYDGTCYYGYQKQPQKITVQQTFEKALKKMTHQNIPTFAASRTDKGVHSQGQTLHFQTTFFLKPTHFQKTLNYLLPPDIRVRQMNFATPNFHARYSAKSKIYQYVFSKKPLNAFNHHFQIFADKLYFDKITKALKFIEGTHNFFAFTSETQPKNFSKTIFQAFLKETSHKYILVFHGNGFLKYMIRFLVGSLIEIGKNKLSLEQFQAMLLGNTTKKATLLAPSKALVLKKIFY
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: LPLA_ECO7I
Sequence: MSTLRLLISDSYDPWFNLAVEECIFRQMPATQRVLFLWRNADTVVIGRAQNPWKECNTQRMEEDNVRLARRSSGGGAVFHDLGNTCFTFMAGKPEYDKTISTSIVLNALNALGVSAEASGRNDLVVKTAEGDRKVSGSAYRETKDRGFHHGTLLLNADLSRLANYLNPDKKKLAAKGITSVRSRVTNLTELLPGITHEQVCEAIREAFFAHYGERVEAEIISPDKTPDLPNFAETFARQSSWEWNFGQAPAFSHLLDERFTWGGVELHFDVEKGHITRAQVFTDSLNPAPLEALAGRLQGCLYRADMLQQECEALLVDFPEQEKELRELSAWMAGAVK
What is the function of this protein?
Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.
What are the official names of this protein?
Lipoate-protein ligase A, Lipoate--protein ligase.
What is the protein family that this protein belongs to?
Belongs to the LplA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STHA_SODGM
Sequence: MQPKYDYDAIIIGSGPGGEGAAMGLTKRGARVAIIERYDNVGGGCTHWGTIPSKALRQAVSRIIEINQSPLHGNTRLPHTGFSDILCHADQVINQQTHMRQGFYERNHCQIFTGEASFVDEHQVQIHYGDNTTETLSAENIVIACGSRPYQPQDVDFDHPRIYDSDSILDLKHDPHHVIIYGAGVIGCEYASIFRGMNVKVDLINTRDRLLAFLDQEMSDALSYHFWENGVVIRHNEEYEEIKGLDDGVEVRFRSGKRMKADCLLYANGRTGNTDTLKLDKVELEADSRGLIKVNSMYQTAARHIYAVGDVIGYPSLASAAYDQGRIAAQVIIKGQANVQLIENIPTGIYTIPEISSVGKTEQELTAMKVPYEVGRAQFKHLARAQIVGMNVGSLKLLFHRETKQILGIHCFGERAAEIIHIGQAIMEQKGEGNTIEYFVNTTFNYPTMAEAYRVAALNGLNRLF
What is the function of this protein?
Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
What are the official names of this protein?
Soluble pyridine nucleotide transhydrogenase, STH, NAD(P)(+) transhydrogenase [B-specific].
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RD21_PHYIT
Sequence: MRLSYILVVVIAVTLQACVCATPVIKEANQAMLANGPLPSIVNTEGGRLLRGVKKRTAEREVQEERMSGAKLSEKGKQFLKWFFRGSDTRVKGRSWR
What is the function of this protein?
Effector that is involved in host plant infection.  Contributes to virulence during the early infection stage, by inhibiting plant defense responses induced by both PAMP-triggered immunity (PTI) and effector-triggered immunity (ETI).
What are the official names of this protein?
RxLR effector protein PexRD21, Core RXLR effector 1.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cell membrane.
Protein: MINE_ECOHS
Sequence: MALLDFFLSRKKNTANIAKERLQIIVAERRRSDAEPHYLPQLRKDILEVICKYVQIDPEMVTVQLEQKDGDISILELNVTLPEAEELK
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: RS19_FINM2
Sequence: MSRSLKKGPFCDEHLMKKVEELNKNDEKKIIKTWSRRSTIFPNFVGHTIAVHDGRKHVPVYITDDMVGHKLGEFVPTRTYKGHIKNEKTSKVRN
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: PGK_ALIB4
Sequence: MKLQEIKNIDITGKKVFIRCDFNVPMDEYNNITDDRRIRSALNTIRYCIDHDCSVILSSHFGRPKGGFEEKYSLLPIAKRLHILLKQDIKMAPGVICDETLQMAKELKAGEILLLENMRFEAGETKNDEELSKKLASMAEIYINDAFGVSHRAHASVEGISKYFDIEHKAAGFLMAKEIKFFHHIIHNPKRPFIAIVGGSKVSGKLEALYNLIPKVDKIIIGGGMAFTFLKARGHEIGNSLVEDDLIPEALKIMEEAKSKGVKLYLPVDVVAAEAFDAEAIAKIATIQEMPKGWMGLDIGPASALLFSEALSDANTILWNGPMGVYEMDRFAKGSTKISHAVANSYATTVVGGGDTADLVRVTGDEDDMTFISTGGGASLELIEGKVLPGVKALVIEEND
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14Z_MYCS5
Sequence: MARKALIEKAKKHPKFSSRAYTRCELCGRPHSVLRKYKICRICFRNLAHEGKIPGVKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: LEU3_METCA
Sequence: MTIKIAVLPGDGIGPEIVAEALKVLDCLRSDFGLAVETEHALIGGAAYDAHGTPFPKETLELCRAADSILLGAVGGPKWEPLDYSLRPERGLLGLRSELELFSNLRPAVLYPQLVSASTLKPEVVAGLDIMIVRELTGGIYFGKPRGRRINEDGEREGYNTLVYSESEIRRIAHSAFQIARKRNRRLCSIDKANVLECTELWREVVIEVGKDYPDVALSHMYVDNAAMQLVRNPKQFDVMLTDNMFGDILSDCAAMLTGSIGMLPSASLAESGKGMYEPIHGSAPDIAGRGIANPIATILSLAMMLRYSFDDAVSAERIGKAVQTALDQGFRTADIASEGTVEVGTAAMGDAIVAALRAV
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIG_PSEPK
Sequence: MSNVRSDKPFTLAGRTFQSRLLVGTGKYRDMEETRLATEASGAEIVTVAVRRTNLGQNAGEPNLLDVLSPDKYTILPNTAGCFDAVEAVRTCRLARELLDGRKSHESRTLVKLEVLADQKTLFPNVIETLKAAEVLVKEGFDVMVYTSDDPIIARQLAEVGCIAVMPLAGLIGTGLGICNPYNLQIILEESKVPVLVDAGVGTASDATIAMEMGCEAVLMNSAIAHAQQPVLMAEAMKHAIVAGRMAYLAGRMPKKLYASASSPLDGLIK
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_AFIC5
Sequence: MALPDFTMRQLLEAGVHFGHQAHRWNPKMADFIFGARNNIHIIDLAQTVPLMHRALQAVSDTVAKGGRILFVGTKRQAQDGVADAAKRSAQYFVNSRWLGGTLTNWKTVSGSIRRLRQLEEMLGSAEGSQYTKKERLTLQRERDKLDRSLGGIKDMGGLPDLIFVIDTNKEDIAIQEAQRLGIPVAAIVDTNCDPKGITYVVPGNDDAGRAIALYCDLIARAAIDGISRAQGDAGIDVGALAAPPQEDAVEASKTEGFQGLAGPRGVADDLKKLSGVSGAIEKKLNDLGIFHYWQIAELDSATAHKIGEEVGLPARVDGWVSQSKSLTADAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RT09_ASHGO
Sequence: MFARMASLRALVPVRALLWRAPVRSVHRAAVRETRIVPQLPTFYSANPAHEAHMDRLEALLRKHTKQQARRVAVERTASDRPRWLSFDQYALIGGTSRLKPTQYRQLVSVLDRLHAIDPQLSNGEIAATLEAFLRKSRLEEQNVVRQELDHLGRACAVGRRKTSSAKVWLVRGSGEVLVNGRTFADYFSKIKDRDAIMYPLRVLDAAGKYNIFAAVRGGGVTGQAEAIMHAVAKALVVFNPLLKTRLHRAGVLTRDYRHVERKKPGKRKARKMPAWVKR
What are the official names of this protein?
37S ribosomal protein S9, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PA2B_GLOBL
Sequence: HLLQFRKMIKKMTGKEPVISYAFYGCYCGSGGRGKPKDATDRCCFVHDCCYEKVTGCKPKWDDYTYSWKNGDIVCGGDDPCKKEICECDRAAAICFRDNLKTYKKRYMAYPDILCSSKSEKC
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that inhibits neuromuscular transmission by blocking acetylcholine release from the nerve termini.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (By similarity).
What are the official names of this protein?
Basic phospholipase A2, PA2-I, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: KDSB_PSESM
Sequence: MTAAFTVVIPARYGSSRFPGKPLKTIAGKPMVQLVWEQARKSSAERVVIATDDARIVEACRAFGAEVLLTRDDHNSGTDRLAEVATQLGLAANAIVVNVQGDEPLIPPAVIDQVAANLAKHPEAGMATLAEPIDDVAALFNPNIVKVSTDINGLALTFSRAPLPWARDALARSKDELPADVPYRRHIGIYAYRAGFLHDFVSWGPCWLENTESLEQLRALWNGVRIHVADALEAPPGGVDTPEDLERVRRLLEA
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXE_RHIL3
Sequence: MRAFWASLDRRWRRSGVGMPPLRWQACLFVTLNAVILSMLLFDAPIGASKAPAPVKHLGELLTGFGDSAWLIYTSILLFFQGRAGYKLLKTARSKAQALYVSWIGAYLFFTVVFSGLLANLLKRAIGRARPDHFHDYGMFSFAPFSGHSAFESFPSGHSTTVGAFFAAFALLFPRYRVAFIACAIWLGMTRVMVGAHYPSDVIAGLAFGAWFSLLTAIVFARCGLLFKLAPDGWPLAKRLFRTA
What is the function of this protein?
Removes the 1-phosphate group from (tetraacyl) lipid A species, has no requirement for the Kdo(2) moiety of lipid A.  Has no 4'-phosphatase activity.  Reduces sensitivity of S. meliloti strain 1021 to the cationic antimicrobial peptide (CAMP) polymyxin B.
What are the official names of this protein?
Lipid A 1-phosphatase.
What is the protein family that this protein belongs to?
Belongs to the lipid A LpxE 1-phosphatase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HRTB_STAES
Sequence: MNLAWKEIKFYKFRFILIMFIIFLMAIMVLFISGLAQGLARENISIFDQIKGNQFVVQKMKEPQLEKSILSRSKQDNISKIIDEKPFKMAGKTFKINGNEENVMAINSVKNHQPNLKSGHYPKNGNQIAINEKLTAEGLYLDDKVKVKGDDTTYKVVGILKNTMYSHSNIVMMDQSKIEQSSNVATFYVTNQLSKSDKNKINHIKGVQTATTDDITSNIASYKAEQTPLDMMIISLYIITAIVLSAFFYVMTIQKTSEIGILKAIGITTKHLLTSLILQISMITFIGVAIAEVVIFLISQILPVSMPFHIDMHNIIIVLVVFMIVGLIGTSLSFIKLIKIDPIEAIGGGQ
What is the function of this protein?
Part of the ABC transporter complex hrt involved in hemin import.  Responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
Putative hemin transport system permease protein HrtB.
What is the protein family that this protein belongs to?
Belongs to the ABC-4 integral membrane protein family. HrtB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DAPD_YERPE
Sequence: MQQLQNVIETAFERRADITPANVDTVTREAITHVIDLLDTGALRVAEKIDGQWVTHQWLKKAVLLSFRINDNQVMEGAETRYYDKVPMKFAGYDEARFQREGFRVVPPATVRKGAFIARNTVLMPSYVNIGAFVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIEDNCFVGARSEVVEGVIVEEGSVISMGVFIGQSTRIYDRETGEVHYGRVPAGSVVVSGNLPSKDGSYSLYCAVIVKKVDAKTRSKVGINELLRTID
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEN2_ASHGO
Sequence: MAKRVAGSKRYVHPLPIEPVVLPPLIAHNPLSWVYWVLAYVTSSNQLPRKIPLEVGADGRYTVTGREQMQYLWEHGFFGTGQLSRSEPTWQARTVDRLQLDTEGIAGHKLEQVTQLRRKQRLEFKRERASFERKRLELRRQGVLESEILEQERLWLKQLRDRELQWEASTGDPSPVRAEDAEIIAEDGASVLPIEKLELMPVEALFLTLALPVLHADAPAILARTLGPQPALPQIERLCRLYAAYHHYRSHGWCVRSGIKFGCDFLLYRRGPPFHHAEFSVMVLAPDERHDYTWYSTVARVVGGAQKTLVLAYVARRAAADQLAALWHARRYMEAFALFEVHELVYRRWLPGKNRE
What is the function of this protein?
Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA.  It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron.  The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini.  There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.  This subunit may anchor the endonuclease complex to the nuclear membrane.  Probably carries the active site for 5'-splice site cleavage (By similarity).
What are the official names of this protein?
tRNA-splicing endonuclease subunit SEN2, tRNA-intron endonuclease SEN2.
What is the protein family that this protein belongs to?
Belongs to the tRNA-intron endonuclease family.
Protein: SGRR_SHIBS
Sequence: MPSARLQQQFIRLWQCCEGKSQDTTLNELAALLSCSRRHMRTLLNTMQDRGWLTWEAEVGRGKRSRLTFLYTGLALQQQRAEDLLEQDRIDQLVQLVGDKATVRQMLVSHLGRSFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRINEENGELEADIAHHWQQISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIADIVSPTPWTLDIHLTQPDRWLPLLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRNTTNQLKIQAFDDFFGYRALIDEVNVWVLPEIADEPAGGLMLKGPQGEEKEIESRLEEGCYYLLFDSRTHRGANQQVRDWVNYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHARTIKSEKPAGLESLTLTFYQDHSEHRVIAGIMQQILASHQVTLEIKEISYDQWHEGEIESDIWLNSANFTLPLDFSLFAHLCEVPLLQHCIPIDWQADAARWRNGEMNLANWCQQLVASKAMVPLIHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDP
What is the function of this protein?
Activates the small RNA gene sgrS under glucose-phosphate stress conditions as well as yfdZ.  Represses its own transcription under both stress and non-stress conditions.  Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain.
What are the official names of this protein?
HTH-type transcriptional regulator SgrR.
Protein: KUP_STRPG
Sequence: MSDSHLTAFDKASKAGFIIALGIVYGDIGTSPLYTMQSLVENQGGVNQVSESFILGSISLIIWTLTLITTIKYVLIALKADNHHEGGIFSLFTLVRKMSPWLIIPAMIGGATLLSDGALTPAVTVTSAIEGLKAVPGLSHIYQNQTNVIITTLVILIVLFGIQRFGTGFIGKIFGPVMFIWFSFLGVSGFFNTLGHLEIFKAINPYYALHLLFSPENHRGIFILGSIFLATTGAEALYSDLGHVGRGNIYVSWPFVKMCIVLSYCGQAAWILANKHSGIELNPFFASVPSQLTVYVVILATLAAIIASQALISGSFTLVSEAMRLKIFPLFRVTYPGANLGQLYIPVINWILFAVTSCTVLYFRTSAHMEAAYGLAITITMLMTTILLNYYLIKEGVKPFLAHLVMTFFALVEFIFFWASAVKFMHGGYVVVILALAIVFVMFIWHAGTRIVFKYVKSLNLNDYKEQIKQLRDDVCFDLYQTNVVYLSNRMQDYMIDRSILYSILDKRPKRARVYWFVNVQVTDEPYTAKYKVDMMGTDYMVRVNLYLGFRMPQTVPRYLRTIVQDLMESGRLPKQEQEYTITPGRDVGDFRFVLIEERVSNARQLSNFERFIMQTKASIKHVTASPMRWFGLQYSEVTLEVVPLILSDVLKLPIKELVPVEDSEA
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TESA_MYCBO
Sequence: MLARHGPRYGGSVNGHSDDSSGDAKQAAPTLYIFPHAGGTAKDYVAFSREFSADVKRIAVQYPGQHDRSGLPPLESIPTLADEIFAMMKPSARIDDPVAFFGHSMGGMLAFEVALRYQSAGHRVLAFFVSACSAPGHIRYKQLQDLSDREMLDLFTRMTGMNPDFFTDDEFFVGALPTLRAVRAIAGYSCPPETKLSCPIYAFIGDKDWIATQDDMDPWRDRTTEEFSIRVFPGDHFYLNDNLPELVSDIEDKTLQWHDRA
What is the function of this protein?
Involved in the synthesis of both phthiocerol dimycocerosates (PDIMs) and phenolic glycolipids (PGLs), which are structurally related lipids non-covalently bound to the outer cell wall layer of M. tuberculosis and are important virulence factors.
What are the official names of this protein?
Thioesterase TesA.
What is the protein family that this protein belongs to?
Belongs to the thioesterase family.