PharMolix/UniProtQA huggingface dataset:
Protein: GLYA1_BORPA
Sequence: MNDLLPAAAAPAGARALPLRHADPEIWRAVDAERQRQMHSIELIASENFVSQAVLDAQGSVMTNKYAEGYPGRRYYGGCRHVDVAERAAIERARRLFGCEYANVQPHSGSQANQAVYLALLAPGDRILGLDLKAGGHLTHGARVNLSGKWFEALSYGVDPVSHRIDMDEVERTARRERPRLIIAGGSAYARVPDFARFRAIADATGALFVADMAHYAGLVAGGAFPSPVPFAHVTTTTTHKTLRGPRGGMILTDDADIARRIDAAVFPGLQGGPLMHVIAAKAVALGEALQPGFRAYARAVIDNARALCARLAEGGLSIVSGGTDCHLGVVDLRPWGLAGNAAERALEEAGITVNKNAVPGDAASPAVTSGIRVGSAACTSRGMGPAEFRQIGDLVLAVLGGLRDGGQAGGRDAVPARAAELSRRFPLPY
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase 1, SHMT 1, Serine methylase 1.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG37_KOMPG
Sequence: MSESIDRVFVKAIGTIRTLSSRTGYGGLPRPPIENRVKLYGLYKQATEGDVAGVMERPLGDSPEAEAAKRKWDAWRSEQGTSKTEAKRQYISYLIDTMKQFASDTTEARELLSELEYLWNQISDVSPNDSSDSESNAGPAQLLQNHAQLLSRDISVVDDPITSSGMDPMYNPSFQRHNSSRFINASTAERLNSLSNYYSNLNPTPPLSSRRYQGSVTPRNVDFIKWQNDINNSINKLNHDLQLLANRRLQSSASDPLYSKRGSDLTHDDFVNDISSSSSNRRFRARRNQPLVSKVLLGTISLLLKLIKTVIKHVAIDAVIIAVLVAVIKRSIIIPNLISNEISLQKIHHSELESNSSIKGDSNGGRLTIVLPFINGKDFFQENSLLGKLLKVFHDYVDHVSRIRLIKRN
What is the function of this protein?
Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy.  Required for both micropexophagy and macropexophagy, but not for the cytoplasm to vacuole transport (Cvt) or autophagy pathways.  Required for functional micropexophagic apparatus (MIPA) and relocation of ATG11 to the peroxisome-sequestering arms of the vacuole.  Binds palmytoyl-CoA but not oleyl-CoA.
What are the official names of this protein?
Autophagy-related protein 37.
What is the protein family that this protein belongs to?
Belongs to the ATG37 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Single-pass membrane protein. Note=Localization to the peroxisome is ATG30-dependent.
Protein: RR4_SPIOL
Sequence: MSRYRGPRFKKIRRLGALPGLTNKRPRAGSDLRNQSRSGKRSQYRIRLEEKQKLRFHYGITERQLLKYVRIARKAKGSTGQVLLQLLEMRLDNILFRLGMAPTIPGARQLVNHRHILVNGRIVDIPSYRCKPQDTIMARDEQKSIALIQNSLDLSPREELPKHLTLNPFPYKGLVNQIIDSKWVGLKINELLVVEYYSRQT
What is the function of this protein?
Component of the chloroplast ribosome (chloro-ribosome), a dedicated translation machinery responsible for the synthesis of chloroplast genome-encoded proteins, including proteins of the transcription and translation machinery and components of the photosynthetic apparatus.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic, Chloroplastic small ribosomal subunit protein uS4c.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: UB2L6_RAT
Sequence: MTASKRVAKELDDLSKELPPYLRHLSSDDANVLVWHMLLLPDQLPYRLKAFGLRIDFPREYPLKPPTLRFTTKIYHPNISEDGLVCLPLISTENWKPYTKAYQVLEALNILVSRPNLEEPVRLELADLLTQDPEMFRKKAEEFTLQYGVDRPS
What is the function of this protein?
Catalyzes the covalent attachment of ubiquitin to other proteins.  Functions in the E6/E6-AP-induced ubiquitination of p53/TP53.  Promotes ubiquitination and subsequent proteasomal degradation of FLT3.
What are the official names of this protein?
Ubiquitin/ISG15-conjugating enzyme E2 L6, E2 ubiquitin-conjugating enzyme L6, Ubiquitin carrier protein L6, Ubiquitin-protein ligase L6.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: BIOY_METTH
Sequence: MSGVILGRYWGGLSQLIYVIIGAAGVPWFADMSGGPEVLLGATGGYLLGFILAALLLGHFVDRHIRARKFTPMLGLMTIANFGLIYIPGLVVLGLWSLKTQGTLPGPWELLVMGLLPFIPGDILKITGAAALTRAITPKEPYGEEIDIQKAEGWRVP
What is the function of this protein?
Probable biotin transporter.
What are the official names of this protein?
Probable biotin transporter BioY.
What is the protein family that this protein belongs to?
Belongs to the BioY family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AB37G_ORYSJ
Sequence: MDREVHRMASLRREGSMWRSGGDVFSRSSSRFQDEDDDEEALRWAALERLPTYDRVRRGILAVSSEDGGAGGEKVEVDVGRLGARESRALIERLVRAADDDHERFLLKLRERMDRVGIDYPTIEVRFENLEVEADVHVGNRGLPTLLNSVTNTVEAIGNALHILPNKKQPMTVLHDVSGIIKPRRMTLLLGPPGSGKTTLLLALAGKLDKDLKVSGKVTYNGHGMHEFVPERTAAYISQHDLHIGEMTVRETLAFSARCQGVGTRYEMLTELARREKAANIKPDHDIDIYMKASAMGGQESSVVTDYILKILGLDICADTVVGNEMLRGISGGQRKRVTTGEMLVGPARALFMDEISTGLDSSTTYQIVNSLRQTIHILGGTAVISLLQPAPETYNLFDDIILLSDGQVVYQGPREHVLEFFEFMGFRCPARKGVADFLQEVTSRKDQGQYWCRRDRPYRFVPVKQFADAFRSFHVGRSIQNELSEPFDRTRSHPAALATSKYGVSRKELLKATIDRELLLMKRNAFMYIFKAVNLTLMALIVMTTFFRTSMRHDRDYGMIYLGALYFALDTVMFNGFAELAMTVMKLPVFFKQRDLLFFPAWAYTIPSWILQIPITFLEVGVYVFITYYVIGFDPSVSRFFKQYLLLLALNQMSSALFRFIAGIGRDMVVSHTFGPLSLLAFAALGGFILARPDVKKWWIWGYWISPLSYAQNAISTNEFLGHSWSQILPGENVTLGVSVLKSRGIFTEAKWYWIGLGALLGYTLLFNLLYTVALSVLSPFTDSHASMSEDALKEKHANLTGEVVEGQKDTKSRKQELELSHIADQNSGINSADSSASRKGMVLPFAPLSISFNDVRYSVDMPEAMKAQGITEDRLLLLKGVSGSFRPGVLTALMGVSGAGKTTLMDVLAGRKTGGYIEGDIRISGYPKKQETFARISGYCEQNDIHSPHVTVYESLVFSAWLRLPSEVDSEARKMFIEEVMDLVELTSLRGALVGLPGVSGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARAAAIVMRTVRNTVNTGRTVVCTIHQPSIDIFEAFDELFLMKRGGEEIYVGPVGQNSSKLIEYFEGIDGVSRIKDGYNPATWMLEVTSSAQEEMLGVDFSEIYRQSELYQRNKELIEELSTPPPGSTDLNFPTQYSRSFITQCLACLWKQNWSYWRNPSYTAVRLLFTIVIALMFGTMFWNLGTRTKKQQDLFNAMGSMYAAVLYIGVQNSGSVQPVVVVERTVFYRERAAGMYSAFPYAFGQVAIELPYIMVQTLIYGVLVYSMIGFEWTVAKFLWYLFFMYFTLLYFTFYGMMAVGLTPNESIAAIISSAFYNVWNLFSGYLIPRPKIPVWWRWYCWICPVAWTLYGLVASQFGDIQHVLEGDTRTVAQFVTDYFGFHHNFLWVVAVVHVVFAVTFAFLFSFAIMKFNFQRR
What is the function of this protein?
May be a general defense protein.
What are the official names of this protein?
ABC transporter G family member 37, OsABCG37, Pleiotropic drug resistance protein 8, OsPDR8.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PFD1_BOVIN
Sequence: MAAPVDLELKKAFTELQAKVIDTQQKVKLADVQIEQLNRTKKHAHLTDTEIMTLVDETNMYEGVGRMFILQSKEAIHNQLLEKQKIAEEKIKELEQKKSYLERSVKEAEDNIREMLMARRAQ
What is the function of this protein?
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it.  Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity).
What are the official names of this protein?
Prefoldin subunit 1.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit beta family.
Protein: YKOD_BACSU
Sequence: MQAFDELLTVEQLSFSYEEDEKPVFQDISFELQKGECVLLLGPSGCGKSSLALCLNGLYPEACDGIQSGHVFLFQKPVTDAETSETITQHAGVVFQDPDQQFCMLTVEDEIAFGLENLQIPKEEMTEKINAVLEKLRITHLKEKMISTLSGGQKQKVALACILAMEPELIILDEPTSLLDPFSAREFVHLMKDLQREKGFSLLVIEHQLDEWAPWIERTIVLDKSGKKALDGLTKNLFQHEAETLKKLGIAIPKVCHLQEKLSMPFTLSKEMLFKEPIPAGHVKKKKAPSGESVLEVSSLSFARGQQAIFKDISFSLREGSLTALVGPNGTGKSTLLSVLASLMKPQSGKILLYDQPLQKYKEKELRKRMGFVFQNPEHQFVTDTVYDELLFGQKANAETEKKAQHLLQRFGLAHLADHHPFAISQGQKRRLSVATMLMHDVKVLLLDEPTFGQDARTAAECMEMIQRIKAEGTAVLMITHDMELVSSYADSVLVLHDTGLAFDGSPAQLFSQETGLVQKAKLTLPLLYEWMAFQEEVRDEATVTSH
What is the function of this protein?
Part of the ABC transporter complex YkoCDEF that could transport hydroxymethylpyrimidine (HMP) and/or thiamine.  Could also transport other HMP-containing products.  Responsible for energy coupling to the transport system (Probable).
What are the official names of this protein?
Putative HMP/thiamine import ATP-binding protein YkoD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RSMH_PHOV8
Sequence: MSEAKQIYHVPVLLNESVDGMNIQPGGIYVDATFGGGGHSKEILSRLDSTAHLYSFDQDEDAEKNIVSDSRFTFVRSNFRYLPNFLRYYGVEGVDAILADLGVSSHHFDDSERGFSFRFEGKLDMRMNKRAGMTAADVVNTYDEERLANIFYLYGELKNSRKLASAIVKARGVKQIVTIGDFLEVIKPLFGREREKKELAKVFQALRIEVNQEMEALKEMLYAATKALKPGGRLVVITYHSLEDRMVKNIMKTGNIEGKAEQDFFGNVQTPFKLVNNKVIVAGNEEVTRNPRSRSAKLRIAEKR
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBEAG_HBVA7
Sequence: MQLFHLCLIISCTCPTVQASKLCLGWLWGMDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTASALYREALESPEHCSPHHTALRQAILCWVELMTLATWVGNNLQDPASRDLVVNYVNTNMGLKIRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRDRGRSPRRRTPSPRRRRSQSPRRRRSQSRESQC
What is the function of this protein?
May regulate immune response to the intracellular capsid in acting as a T-cell tolerogen, by having an immunoregulatory effect which prevents destruction of infected cells by cytotoxic T-cells.  This immune regulation may predispose to chronicity during perinatal infections and prevent severe liver injury during adult infections.
What are the official names of this protein?
External core antigen, HBeAg, Precore protein, p25.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus precore antigen family.
What are the subcellular locations of this protein?
Secreted. Host nucleus.
Protein: MDPB_EMENI
Sequence: MTLQPTFEGRTPEQCLNVHTDSHPDITGCQAALFEWAESYDSKDWDRLKQCIAPFLRIDYRAFLDKLWEKMPAEEFVAMVSHPHFLGNPLLKTQHFVGTMKWEKVDDSKIVGYHQMRVAHQKHLDSQMKEVVAKGHGHGSATVTYRKINGEWKFAGIEPNIRWTEFGGEGIFGPPEKEENGVAADDQVMNSNGSSEVEERNGHVVNKAVEVRSV
What is the function of this protein?
Scytalone dehydratase-like protein; part of the gene cluster that mediates the biosynthesis of monodictyphenone, a prenyl xanthone derivative (PubMed:20139316, PubMed:21351751, PubMed:22730213).  The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) mdpG (PubMed:20139316).  The atrochrysone carboxyl ACP thioesterase mdpF then breaks the thioester bond and releases the atrochrysone carboxylic acid from mdpG (PubMed:20139316).  The atrochrysone carboxylic acid is then converted to atrochrysone which is further transformed into emodin anthrone (PubMed:20139316).  The next step is performed by the anthrone oxygenase mdpH that catalyzes the oxidation of emodinanthrone to emodin (By similarity).  Emodin is further modified to yield monodictyphenone via several steps involving mdpB, mdpC mdpJ, mdpK and mdpL (PubMed:20139316, PubMed:21351751).  These enzymes with xptA, xptB and xptC are also proposed to be involved in the synthesis of shamixanthone from emodin (PubMed:22730213).  Especially, direct reduction of emodin by the short chain dehydrogenase mdpC followed by dehydration catalyzed by the scytalone dehydratase-like protein mdpB gives loss of oxygen and formation of chrysophanol intermediate in two simple steps (PubMed:22730213).
What are the official names of this protein?
Scytalone dehydratase-like protein mdpB, Monodictyphenone synthesis protein B.
What is the protein family that this protein belongs to?
Belongs to the scytalone dehydratase family.
Protein: ATPL_ECO8A
Sequence: MENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPDLIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL18_BURMS
Sequence: MDKTQSRLRRARQTRIKIAELQVARLAVHRTNTHIYAQVFSPCGTKVLASASTLEAEVRAQLADKSGKGGNVAAATLIGKRIAEKAKAAGIESVAFDRSGFRYHGRVKALAEAAREAGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: THI4_METIK
Sequence: MDVRLRADEYATTRAILKSAFDMWLDIIDVDVAIVGGGPSGLTAARYIAKEGYKVVVLERHLAFGGGTWGGGMGFPYIVVEEPADEILREVGVKLEKVEGEDGLYTADSVEVPAKLAVGAIDAGAKVLTGIVVEDLVLRENRVAGVVINSYAIEKAGLHIDPITITAKYVVDATGHDASVVTTLSRKNPELGLEVPGEKSMWAEKGENALLRNTREVYPGLFVCGMAANAVYAGHRMGAIFGGMYISGKKCAEMIVEKLKNNE
What is the function of this protein?
Involved in the biosynthesis of the thiazole moiety of thiamine.  Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
What are the official names of this protein?
Thiamine thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the THI4 family.
Protein: RL9_FRATH
Sequence: MQVILKEKVENLGVLGDIVNVKPGYARNFLIPFGKAVQATQANIKAFEAQKAELEKAEKARFEAAVAVADAIKDKVYTIAAQAGEGGKLFGSVGIAEVAEAVSNQSGKKIEKSQVRMPEGVIRSIGEFELTVHVYTDVDADIKVNVVAAEA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: BPIB1_RAT
Sequence: MTNPWIVSLLLGATLVQANLYPPAVLNLGPEVIKKHLTQALENHDATAILQELPLLRGMQDKSGSIPILDSFVNTVLRYIIWMKVTSANILQLVVQPSTYDQELVVRIPLDMVAGLNTPLIKTIVEFQMSTEVQALIRVERSKNGPARLNLSDCSSNESTLRLSLLHKLSFVVNSLAKNVMNLLMPALPQIVKSHLCPVIQQAFDDMYEDFLRLTTAPIALSPGALEFDLLSPAIQDSNILFNLKAKLLDSQARVTNWFNGSATPLMETTPDRAPFSLTVRQDLVNAIVTTLIPQEELVILLRFVIPDVARQLQMDIKEINAEAANKLGPTQMLKIFTHSTPHIVLNEGGATAAQSVVLEVFPTNTDVRPFFSLGIEASYEAQFFIAENRLMLNFNNVSIERIKLMISDIKLFDPEVLKDTLTKILEYTLLPNENGKLRTGIPMSMPKALGYEKAMWSVSKGALKLTPASS
What is the function of this protein?
May play a role in innate immunity in mouth, nose and lungs.  Binds bacterial lipopolysaccharide (LPS) and modulates the cellular responses to LPS (By similarity).
What are the official names of this protein?
BPI fold-containing family B member 1, Long palate, lung and nasal epithelium carcinoma-associated protein 1.
What is the protein family that this protein belongs to?
Belongs to the BPI/LBP/Plunc superfamily. Plunc family.
What are the subcellular locations of this protein?
Secreted.
Protein: NRDIL_STRP1
Sequence: MPQITLVFISLSGNTLSFVKRLSLYLADNYDYHVKQINIKDLKHETFPVKEEFVAILPTYLEGGNGVDSGDVEILTTPLGEFIAAHGNAQRCLGIIGSGNKNFNHQYCLTAKQYAKRFGFPLLGDFELRGTPDDISRLAQVIMEASSRHSSNDTQTLPNS
What are the official names of this protein?
Putative NrdI-like protein.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: RL33_THEFY
Sequence: MAATDVRPKITLACQECKHRNYITRKNRRNTPDRLELRKYCPNCRTHREHRETR
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: NAR1_PICGU
Sequence: MSALLSADDLNDFISPGIACIKPTVTENRSQEASEYGEVEIQIDENGKPLEISKIDGATKNLSPAQISLADCLACSGCITSAEEILVAQHSHNELIKALKEKKTNNKIFVASISHQARASLATAYYMKVSDIDRLLVDLLVNQMGFTYVVGTGLGRKLSLINESQSVIERKEHGFQGPILSSICPGWVLYAEKTHPHVLSRISDTKSPQQITGCLLKSLTAHQLEVERDQIYHLSIMPCFDKKLESARPEQDPSLVSNDVDCVLTPKELVTLLDECKDKFSLTFDALSHSSGSLTDLYQSCAPANWPYVELSWSSDSGSSSGGYGYNYLQLLQSHLCLRDPQQYQPQNFRLESVAGRNKDIYELRLVYNDNQVASSAIVNGFRNIQNLVRKLKPTSSTTTTKTNPLVARRKARLSSKRSESGAQDVQQADASKCDYVEIMACPNGCINGGGQINSPTDEDQKLWVSKTLTRYGSIPMVDLSSDSSLTLELMAWCREFCINYNVPESRLLKTWFHEVEQPTDQAAILVGSKW
What is the function of this protein?
Component of the cytosolic Fe/S protein assembly machinery.  Required for maturation of extramitochondrial Fe/S proteins.  May play a role in the transfer of pre-assembled Fe/S clusters to target apoproteins (By similarity).
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor NAR1, Nuclear architecture-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the NARF family.
Protein: RL15_CTEID
Sequence: MGAYKYMQELWRKKQSDVMRFLLRVRCWQYRQLSSLHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQIKFARSLQSVAEERAGRHCGGLRVLNSYWVGEDSTYKFFEVILIDTFHKAIRRNPDTQWITKAVHKHREMRGLTSAGKKSRGLGKGHKFHLTIGGSRRAAWKRRNTLQLHRYR
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CMOA_ECOBW
Sequence: MSHRDTLFSAPIARLGDWTFDERVAEVFPDMIQRSVPGYSNIISMIGMLAERFVQPGTQVYDLGCSLGAATLSVRRNIHHDNCKIIAIDNSPAMIERCRRHIDAYKAPTPVDVIEGDIRDIAIENASMVVLNFTLQFLEPSERQALLDKIYQGLNPGGALVLSEKFSFEDAKVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVETHKARLHNAGFEHSELWFQCFNFGSLVALKAEDAA
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: ORN_NEIG1
Sequence: MEMTGLNPETDRIIEVAMIITDSDLNVLAQSEVYAIHQSDDLLDNMDEWNTATHGRTGLTQRVRESSHTEAEVEQKLLDFMSEWIPGRATPMCGNSIHQDRRFMVKYMPKLENYFHYRNLDVSTLKELAKRWNPPIAKSVVKRGSHKALDDILESIEEMRHYREHFLISAPKAEAQ
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPGB_ECO45
Sequence: MSELLSFALFLASVLIYAWKAGRNTWWFAATLTVLGLFVVLNITLFASDYFTGDGINDAVLYTLTNSLTGAGVSKYILPGIGIVLGLTAVFGALGWILRRRRHHPHHFGYSLLALLLALGSVDASPAFRQITELVKSQSRDGDPDFAAYYKEPSKTIPDPKLNLVYIYGESLERTYFDNEAFPDLTPELGALKNEGLDFSHTQQLPGTDYTIAGMVASQCGIPLFAPFEGNASASVSSFFPQNICLGDILKNSGYQNYFVQGANLRFAGKDVFLKSHGFDHLYGSEELKSVVADPHYRNDWGFYDDTVLDEAWKKFEELSRSGQRFSLFTLTVDTHHPDGFISRTCNRKKYDFDGKPNQSFSAVSCSQENIATFINKIKASPWFKDTVIVVSSDHLAMNNTAWKYLNKQDRNNLFFVIRGDKPQQETLAVKRNTMDNGATVLDILGGDNYLGLGRSSLSGQSMSEIFLNIKEKTLAWKPDIIRLWKFPKEMKEFTIDQQKNMIAFSGSHFRLPLLLRVSDKRVEPLPESEYSAPLRFQLADFAPRDNFVWVDRCYKMAQLWAPELALSTDWCVSQGQLGGQQIVQHVDKTTWQGKTAFKDTVIDMARYKGNVDTLKIVDNDIRYKADSFIFNVAGAPEEVKQFSGISRPESWGRWSNAQLGDEVKIEYKHPLPKKFDLVITAKAYGNNASRPIPVRVGNEEQTLVLGNEVTTTTLHFDNPTDADTLVIVPPEPVSTNEGNILGHSPRKLGIGMVEIKVVEREG
What is the function of this protein?
Transfers a phosphoglycerol residue from phosphatidylglycerol to the membrane-bound nascent glucan backbones.
What are the official names of this protein?
Phosphoglycerol transferase I, Phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the OpgB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DPH2_CRYNJ
Sequence: MSDAFSTPADHALSHPELEAILENAQAGPSSIGDGAEGMSIEEAFEVDETVRRVLEGDYKTIGLQFPDELLPSSVSVYRAIQTRIAHTGAQAYVLADSTYGNCCPDVLSCLHLPADFLVHYGHACLTPTDALPVHYVFPRQKLDVKQAVESLLAASKNELDGDGRKGIVVVWDVSYDWLANDIRDTFSQDSTIQISFASIQKPTLASQKGLKDVKGKTPALRSVEPPQGLEMNDCVLWYIGEEGRSCMNLQMTHANNPLFIYSPSSQSVSPLHRTTSRLLSRRLFALHQALSADVFGLIVSNIGLASSKPLLAQLREDLKRAKKKSYTLSVGRLNPAKLANFAEIECFVLVGCAEGGVVDSKDFLRPIITPWELELALQGPDHVWAPENWTLDLGTVLKDAQEREIKIKQDSSTADSDDDSLEFSLITGTMRTKKRFAFGNGTHTLENNKLLGDGGVQDLTLRNQNFSLSKLESAGSTFLASREFQGLEPRYGMDEPSVLEQGRSGVARGYTEEK
What is the function of this protein?
Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2.  DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase, predominantly CBR1 (By similarity).  Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit (By similarity).
What are the official names of this protein?
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2, Diphthamide biosynthesis protein 2, Diphtheria toxin resistance protein 2, S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the DPH1/DPH2 family. DPH2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF_HELPG
Sequence: MALLEIIHYPSKILRTISKEVVSFDAKLHQQLDDMHETMIASEGIGLAAIQVGLPLRMLIINLPREDGVQHKEDCLEIINPKFIETGGSMMYREGCLSVPGFYEEVERFEKVKIEYQNRFAEVKVLEASELLAVAIQHEIDHLNGVLFVDKLSILKRKKFEKELKELQKKQKHK
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: PUR7_SYNJA
Sequence: MPFSPQELLYEGKAKRIYRTADPRVYLCQYKDDATAFNAQKRGSIAGKGEVNCTVSSHVFAYLAQQGIPNHFLAQTGPTEMQVRALHILPLEVVVRNRTAGSLCQRLGLEQGLPIEPPLVEFYYKNDALGDPLVTPDHIRLLHLATPEQVEKLGSLALAVNTHLGNFWRRCRLELVDFKLEFGLDEEGQIWLADEISPDTCRLWDLQGTEPRVLDKDLFRFDLGDPAAGYQEVLQRVLQATDPNLPSPAARERGRG
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: RBFA_LEPBL
Sequence: MNPIRRRKIEAEAVRTVAMMILSGKVKDPRVHMVSVHRAEISEDGKNMKVFVTAICTDKKKLKVLSGLNSAAGLFQTTLSGKLGLRITPRMQFLWDEEYIQSLDESLRLTRKPTSAD
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT4_ARATH
Sequence: MGFLFGLFIGIAVSFGLVVAFARYSSVRSTRRADLAKTIAAFARMTVQDSRKLLPGDFYPSWVVFSQRQKLNWLNLELEKIWPYVNEAASELIKSSVEPVLEQYTPAMLASLKFSKFTLGTVAPQFTGVSILESESGPNGITMELEMQWDGNPKIVLDVKTLLGVSLPIEVKNIGFTGVFRLIFKPLVDEFPCFGALSYSLREKKGLDFTLKVIGGELTSIPGISDAIEETIRDAIEDSITWPVRKIIPILPGDYSDLELKPVGKLDVKVVQAKDLANKDMIGKSDPYAIVFIRPLPDRTKKTKTISNSLNPIWNEHFEFIVEDVSTQHLTVRVFDDEGVGSSQLIGAAQVPLNELVPGKVKDIWLKLVKDLEIQRDTKNRGQVQLELLYCPLGKEGGLKNPFNPDYSLTILEKVLKPESEDSDATDMKKLVTSKKKDVIVRGVLSVTVVAAEDLPAVDFMGKADAFVVITLKKSETKSKTRVVPDSLNPVWNQTFDFVVEDALHDLLTLEVWDHDKFGKDKIGRVIMTLTRVMLEGEFQEWFELDGAKSGKLCVHLKWTPRLKLRDAS
What is the function of this protein?
May be involved in membrane trafficking.
What are the official names of this protein?
Synaptotagmin-4, NTMC2T2.2, Synaptotagmin D.
What is the protein family that this protein belongs to?
Belongs to the synaptotagmin family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.