PharMolix/UniProtQA huggingface dataset:
Protein: CYB_XENBC
Sequence: MKTPIRKTHPVMKIANTALVDLPSPSNISTWWNFGSLLGLFLTMQIITGIILAMHYTSEVDMAFDSISHITRNVNYGWLMRTMHMNGAAFMFICMYAHMGRGMYYSSYMLAETWNIGIIIMIATMATAFMGYVLPWGQMSFWGATVITNLVSAIPYIGTDIVYWLWGGFSVGKATLSRFFAFHFVLPFVLIALSGVHLLFLHQTGSNNPLGLNSNLDKIPFHSFFSWKDLLGFAXMILIFCTITLTFPLIMGDPENFNPANPLSTPPHIQPEWYFLFAYAILRSIPNKLGGVVALVGSLIIPATMMLTHKSMLQPMSFRPISQVIFWLFCANFIALSWIGAAPVEDPYITLGQVFSMLYFLFFLTAPMINMLEKKLSLKQ
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ELH1_APLPA
Sequence: MGRPSYRSAAAISLLMCLILSALCASSESAVVHGSSFATERAVKSSPYLVLSPADEMVGMSTANEAFDKSPSYYDDDDDDFVKNEKRRLRFHKRRIRFNKRPQEVSGLKPVMMSRASASADENSLFDLYNTDGAMYQRDLRAPRLRFYSLRKRAAGDEDKSEENNPETESHSRRKRSALTPSIRSLRSSLESGIAKRISINQDLKAIADMLIVEQKQEREKYLADLRQRLLNKGKRSSEVALAASDKGDEERELLNTLSNLLE
What is the function of this protein?
Beta-BCP specifically excites 2 neurons, L1 and R1, in the abdominal ganglion.
What are the official names of this protein?
ELH type 1.
What is the protein family that this protein belongs to?
Belongs to the molluscan ELH family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y540_STAAN
Sequence: MKLFIILGALNAMMAVGTGAFGAHGLQGKISDHYLSVWEKATTYQMYHGLALLIIGVISGTTSINVNWAGWLIFAGIIFFSGSLYILVLTQIKVLGAITPIGGVLFIIGWIMLIIATFKFAG
What are the official names of this protein?
UPF0382 membrane protein SA0540.
What is the protein family that this protein belongs to?
Belongs to the UPF0382 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS15_PORGI
Sequence: MYLDSAKKAELFEKYGKSVKDTGSPESQIALFTFRIAHLTEHLRQNKKDFATERSLKMLVGKRRRMLDYLIKVDIERYRAIIKELGIRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: RNH2_PELTS
Sequence: MVSGLTVAEIRKLAGSRAGLDEDFLRALACDKRAGVAEIYRRLKRDENKMAAEAERLQKLYIYENSLIAQGYSPVAGVDEAGRGPLAGPVVAAAVILPPVADLALAGLNDSKKLNPSKRAELAARIKKVALAWSAGISTVEEIFNENIHAASLTAMRRAVLKLKIRPAYLLVDGYRISRLELPQLALTGGDGLSASVAAASILAKVLRDRLMDFYHVQYPQYGFNRHKGYATPEHLAALERYGPCPLHRAGYRPVKNCGSRQKCEG
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_STRMU
Sequence: MSRKPIIAGNWKMNKTAAEAREFIDAVKNNIPSNNLVDTVIGSPALFLEGMKKGVKGTELQVAAQNCYWEDFGAFTGETSPAALAALGVDYVIIGHSERRDYFHETDQEINKKAHAIFKHKMTPILCCGESLETYEAGKTAEWIEGQITADLKGLSAEQVSSMVIAYEPIWAIGTGKSADANIADDICGVVRATVEKLYGKEVAQAVRIQYGGSVKPENVAEYMAKENVDGALVGGASLQADSFLALLDFVK
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IL23A_MOUSE
Sequence: MLDCRAVIMLWLLPWVTQGLAVPRSSSPDWAQCQQLSRNLCMLAWNAHAPAGHMNLLREEEDEETKNNVPRIQCEDGCDPQGLKDNSQFCLQRIRQGLAFYKHLLDSDIFKGEPALLPDSPMEQLHTSLLGLSQLLQPEDHPRETQQMPSLSSSQQWQRPLLRSKILRSLQAFLAIAARVFAHGAATLTEPLVPTA
What is the function of this protein?
Associates with IL12B to form the pro-inflammatory cytokine IL-23 that plays different roles in innate and adaptive immunity (PubMed:11114383, PubMed:11390512, PubMed:16670770).  Released by antigen-presenting cells such as dendritic cells or macrophages, binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R to activate JAK2 and TYK2 which then phosphorylate the receptor to form a docking site leading to the phosphorylation of STAT3 and STAT4 (By similarity).  This process leads to activation of several pathways including p38 MAPK or NF-kappa-B and promotes the production of pro-inflammatory cytokines such as interleukin-17A/IL17A (PubMed:19900478).  In turn, participates in the early and effective intracellular bacterial clearance (PubMed:16157683).  Promotes the expansion and survival of T-helper 17 cells, a CD4-positive helper T-cell subset that produces IL-17, as well as other IL-17-producing cells (PubMed:16648837).
What are the official names of this protein?
Interleukin-23 subunit alpha, IL-23 subunit alpha, IL-23-A, Interleukin-23 subunit p19, IL-23p19.
What is the protein family that this protein belongs to?
Belongs to the IL-6 superfamily.
Protein: AROA_ECOLC
Sequence: MESLTLQPIARVDGTINLPGSKSVSNRALLLAALAHGKTVLTNLLDSDDVRHMLNALTGLGVSYTLSADRTRCEIIGNGGPLHAEGALELFLGNAGTAMRPLAAALCLGSNDIVLTGEPRMKERPIGHLVDALRLGGAKITYLEQENYPPLRLQGGFTGGNVDVDGSVSSQFLTALLMTAPLAPEDTVIRIKGDLVSKPYIDITLNLMKTFGVEIENQHYQQFVVKGGQSYQSPGTYLVEGDASSASYFLAAAAIKGGTVKVTGIGRNSMQGDIRFADVLEKMGATICWGDDYISCTRGELNAIDMDMNHIPDAAMTIATAALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDYIRITPPEKLNFAEIATYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQLARISQAA
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIP_SHV2C
Sequence: MANEGEEIELTEFPETEKERKDEEKLSSCSEETTNTSSSSGSDHVPVPIEVNVIIQNSSRTEDELQNSKEIELTGFQGKLSSCSEETTAPSSSYSSKQASVFIEENGDNETSTYRPQNVLTNLNSLYTTFEDARAQGKGMVRHKSEDLQSFLEKYPPDFRKPKRDLSATWDPGMPTPPLPPRPANLGERQASTVRLHVKESNCKQPRERKANERNIVKDLKRLENKINVIICLVVVILAVLLLVTVLSILHIGMKS
What is the function of this protein?
Plays a critical role in virus induced T-cell transformation.  Binds to T-cell-specific tyrosine kinase LCK SH2 and SH3 domains, thereby activating its kinase activity.  Once phosphorylated by host LCK, forms a complex with at least STAT 1 and 3, resulting on the phosphorylation of STAT3 and presumably STAT1, and their migration into the nucleus to induce transcription of target genes.  Stimulates host ILF3/NF-AT-90 activity.  Association with host NXF1/TAP transduces the signal up-regulating surface expression of adhesion molecules as well as activating NF-kappa-B activity.  Acts synergistically with StpC to stimulate NF-kappa-B activity and interleukin-2 gene expression.  Activation of NF-kappa-B protects lymphocytes from apoptosis, thereby facilitating viral induced cell transformation.  May cause down-regulation of host LCK and cell apoptosis when stably overexpressed ex vivo.  Interaction with WDR48 induce degradation of T-cell receptor in a lysosome-dependent fashion, when both proteins are overexpressed.  The biological effect of this interaction remains controversial since no T-cell receptor degradation is observed in infected cells.
What are the official names of this protein?
Tyrosine-protein kinase-interacting protein, Tip.
What are the subcellular locations of this protein?
Host cell membrane; Single-pass membrane protein.
Protein: OAT_HALH5
Sequence: MQSSTSAVIEKTEKYGAKNYHPLPIVISEAKGVWVKDPEGRKYLDMLSAYSAVNQGHCHPKIIQALKDQADKITLTSRAFHNDQLAPFYEKVSKLTGKNMLLPMNTGAEAVETAVKAARRWAYDVKGVPDNQAEIIVCEDNFHGRTMTAVSLSSNDEYKRGFGPMLPGIKVIPYGDLEALKAAITSHTAAFLVEPIQGEAGIRIPQEGFLKEAYALCKRENVLFIADEIQSGLGRSGKWFACDWEDVKPDMYILGKALGGGVFPISVVCADRDILGVFEPGSHGSTFGGNPLACAVSIAALEVLEEEKLVERSYEYGNYLLTKLKEIDNPIIKDVRGRGLFIGVELHEPARKYCEQLKEEGLLCKETHETVIRFAPPLVISKEDLDWAIEKIYYVLKP
What is the function of this protein?
Catalyzes the interconversion of ornithine to glutamate semialdehyde.
What are the official names of this protein?
Ornithine aminotransferase, OAT, Ornithine--oxo-acid aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily.
Protein: YRAN_SHISS
Sequence: MATVPTRSGSPRQLTTKQTGDAWEAQARRWLEGKGLRFIAANVNERGGEIDLIMREGRTTVFVEVRYRRSALYGGAAASVTRSKQHKLLQTARLWLARHNGSFDTVDCRFDVVAFTGNEVEWIKDAFNDHS
What are the official names of this protein?
UPF0102 protein YraN.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: Y1464_STAAC
Sequence: MNAYDAYMKEIAQQMRGELTQNGFTSLETSEAVSEYMNQVNADDTTFVVINSTCGCAAGLARPAAVAVATQNEHRPTNTVTVFAGQDKEATATMREFIQQAPSSPSYALFKGQDLVYFMPREFIEGRDINDIAMDLKDAFDENCK
What are the official names of this protein?
UPF0403 protein SACOL1464.
What is the protein family that this protein belongs to?
Belongs to the UPF0403 family.
Protein: ZDH13_MACFA
Sequence: MEGPGLGSQCRNHSHGPHPPGFGRYGICAHENKELANAREALPLIEDSSNCDIVKATQYGIFERCKELVEAGYDVRQPDKENVSLLHWAAINNRLDLVKFYISKGAVVDQLGGDLNSTPLHWAIRQGHLPMVILLLQHGADPTLTDGEGFSSIHLAVLFQHMPIIAYLISKRQSVNMTDVNGQTPLMLSAHKVIGPEPTGFLLKFNPSLNVVDKIHQNTPLHWAVAAGNVNAVDKLLEAGSSLDIQNVKGETPLDMALQNKNQLIIHMLKTEAKMRTNQKFRLWRWLQKCELFLLLMLSVITMWAVGYILDFNSDSWLLKGCLLVTLFFLTSLFPRFLVGYKNLIYLPTAFLLSSIFWIFMTWFILFFPDLAGAPFYFSFIFSIVAFLYFFYKTWATDPGFTKASEEEKKVNIITLAETGCLDFRTFCTSCLIRKPLRSLHCHVCNSCVARYDQHCLWTGRCIGFGNHHYYIFFLFFLSMVCGWIIYGSFIYWSNHCATTFKEDGLWTYLNQIVACSPWVLYILMLATFHFSWSTFLLLNQLFQIAFLGLTSHERISLLKQSKHMKQTLSLRKTPYNLGFMQNLADFFQCGCFGLVKPCVVDWTSQYTMVFHPAREKVLRSV
What is the function of this protein?
Palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates.  Palmitoyltransferase for HTT and GAD2.  May play a role in Mg(2+) transport.
What are the official names of this protein?
Palmitoyltransferase ZDHHC13, Zinc finger DHHC domain-containing protein 13, DHHC-13.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Low extracellular Mg(2+) induces increase in Golgi and in post-Golgi vesicles.
Protein: PLD3_MOUSE
Sequence: MKPKLMYQELKVPVEEPAGELPLNEIEAWKAAEKKARWVLLVLILAVVGFGALMTQLFLWEYGDLHLFGPNQRPAPCYDPCEAVLVESIPEGLEFPNATTSNPSTSQAWLGLLAGAHSSLDIASFYWTLTNNDTHTQEPSAQQGEEVLQQLQALAPRGVKVRIAVSKPNGPLADLQSLLQSGAQVRMVDMQKLTHGVLHTKFWVVDQTHFYLGSANMDWRSLTQVKELGVVMYNCSCLARDLTKIFEAYWFLGQAGSSIPSTWPRSFDTRYNQETPMEICLNGTPALAYLASAPPPLCPSGRTPDLKALLNVVDSARSFIYIAVMNYLPTMEFSHPRRFWPAIDDGLRRAAYERGVKVRLLISCWGHSDPSMRSFLLSLAALHDNHTHSDIQVKLFVVPTDESQARIPYARVNHNKYMVTERASYIGTSNWSGSYFTETAGTSLLVTQNGHGGLRSQLEAVFLRDWESPYSHDLDTSANSVGNACRLL
What is the function of this protein?
5'->3' DNA exonuclease which digests single-stranded DNA (ssDNA) (PubMed:30111894).  Regulates inflammatory cytokine responses via the degradation of nucleic acids, by reducing the concentration of ssDNA able to stimulate TLR9, a nucleotide-sensing receptor in collaboration with PLD4 (PubMed:30111894).  May be important in myotube formation.  Plays a role in lysosomal homeostasis.  Involved in the regulation of endosomal protein sorting (By similarity).
What are the official names of this protein?
5'-3' exonuclease PLD3, Choline phosphatase 3, Phosphatidylcholine-hydrolyzing phospholipase D3, Phospholipase D3, PLD 3, Schwannoma-associated protein 9, SAM-9.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Lysosome lumen. Early endosome membrane; Single-pass type II membrane protein. Late endosome membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein. Endosome membrane; Single-pass type II membrane protein. Note=Localizes to ER-associated vesicles in differentiating myotubes. The soluble form in lysosome arises by proteolytic processing of the membrane-bound form.
Protein: TIMP_ECOLI
Sequence: MKIRCFCIVLIVSGALLTEVNNNRSLSGDNLLVVNNLQSSK
What is the function of this protein?
Toxic component of a probable type I toxin-antitoxin (TA) system.  Neutralized by sRNA antitoxin TimR which binds to the 5' UTR of timP mRNA and inhibits translation.
What are the official names of this protein?
Putative toxic protein TimP.
What is the protein family that this protein belongs to?
Belongs to the TimP toxin family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein. Note=The signal sequence is not cleaved and anchors the protein in the cell inner membrane.
Protein: SYR_METM6
Sequence: MDVENLIITTLKDKVKELTGTEMDIRLEEPPAINMGDYSTNISFRLAKDLKKAPKMIAEDIANSLSISGIERIEAVNGYINFFMNYPDFSKETVSKITSEKENFGKLEKRGEKVILEHTSANPNGPFHIGHGRNMVIGDSLKRILIASGYDVETQYYVNDMGRQEAIVVFGNERFELDKSKKADHAIGEVYVETNKLLAENEELEQEILNLMKNYESACEAGIENELTEKFKNAVDYSLGGFKETLSTLNIYHDKFVWESEFVKSGMVRDVIKRLMDTGKVVEDEVFRLDLSDYGLEKKLVLARLNGTSLYSTRDIAYHINKMENCDFAVNLLGADHKLTAVLVNKTLALLGYNEAEVVFYEFISLPEGSMSTRRGRFISMDELFEEAKSRAAEEVRKRGVAQSEEEIEEIAKKIAVGAVRYNIVRIAPEKPMVFRWDEALDFEKVGCPVIQYAHARCSRILENVENISNDNLFAYEMNENEKTIVKLLSKLPKIVEKAAEVRKPQIVANYVLDVAQGFNKFYANCPVLKEENETIKNSRLAIVSTTKTVLENTLDLLGIEMPGKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMNB_DESVM
Sequence: MLPGTFFEVLKNEGVVAIATQGEDGPHLVNTWNSYLKVLDGNRIVVPVGGMHKTEANVARDERVLMTLGSRKVAGRNGPGTGFLIRGSAAFRTDGPEFEAIARFKWARAALVITVVSAEQTL
What is the function of this protein?
Functions as a redox protein with a potential of -325 mV.
What are the official names of this protein?
FMN-binding protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KMO_YARLI
Sequence: MHEVTVVGAGLVGCLAALAFADRGHKVALYDARPDLRSEAELKNASLRSINLAVSARGIEALRSVDTKMAERVLADIIPMYGRMIHDLQGGQHAQAYGLWGECINSIDRAQLNRTMLDVIEDNANITFFPEHKLTNISLSRKDKKYQRPTSTFETKEGEERVVESDYIIGADGAFSKTRDRLQRYVRMNYAQQYIDCVYLELKIPKADGPDPFSISPNHLHIWPRHKYMLIALANGDGSFTSTLFAPPALMEQVCESQNTFISFFKEQFPDAYELMGESQILESYENNPRSPLVSLKCSPYNHKGECLLVGDAAHCMVPFYGQGMNAGFEDIRVLMEILDEKKWNVEEAFNTYTERRHKDLVAIVDLAMRNYVEMSHSVVSLPYLIRKKVDGVLGRVFSSAWVPLYSMVSFRADIPYSKALSRSARQDRIIGNIVNWTSFAGLVGMGALFYYKGRHLFGRLFE
What is the function of this protein?
Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn).  Required for synthesis of quinolinic acid.
What are the official names of this protein?
Kynurenine 3-monooxygenase, Biosynthesis of nicotinic acid protein 4, Kynurenine 3-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
What are the subcellular locations of this protein?
Mitochondrion outer membrane.
Protein: RS10_MARSD
Sequence: MVSMTSDRIRIKLKAYDYRILDKAVTEIVDTARNTGAAIAGPIPLPTQISRTTIQRSVHVDKKSREQFEMRIHKRLLDILEPTQQTVDALGKLSLPAGVDVEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RUVC_HELHP
Sequence: MHILGIDPGSRNCGYAIINYAPHVNSLKLIEAGIIKIKERDLQTQIMEFVEGIDLVIKNIHIDEVAIEDIFFAYNPQSVIKLAQFRGALSLKILQEIGNFSEYTPLQVKKAITGNGKADKTQVAFMVKRILGLKGEIKPLDITDAIAIAITHSQRIKTNDVHSTPNLQRAMPLKSLSANPSKGCI
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: MUTS2_BACC0
Sequence: MLERTLRVLEYNKVKEQLLEHTASSLGRDKVKHLVPSTDFEEIVEMQDTTDEAAKVIRLKGSAPLGGITDIRSNVKRAKIGSMLSPNELLDIANTMYGSRNMKRFIEDMVDNGVELPILETHVAQIVSLYDLEKKITNCIGDGGEVVDSASDKLRGIRTQIRTAESRIREKLENMTRSSNAQKMLSDSIVTIRNERYVIPVKQEYRGVYGGIVHDQSASGQTLFIEPQVIVELNNALQEARVKEKQEIERILLMLTEEVAVEADIVLSNVEVVANLDFIFAKAFYAKRIKATKPIVNNERYMDLRQARHPLIDPEVIVPNNIMLGKDFTTIVITGPNTGGKTVTLKTVGICVLMAQSGLHIPVMDESEICVFKNIFADIGDEQSIEQSLSTFSSHMVNIVDILEKADFESLVLFDELGAGTDPQEGAALAISILDEVCNRGARVVATTHYPELKAYGYNREQVINASVEFDVNTLSPTYKLLIGVPGRSNAFEISKRLGLSDRVIDQARNHISTDTNKIENMIAKLEESQKNAERDWNEAEALRKQSEKLHRELQRQIIEFNEERDERLLKAQKEGEEKVEAAKKEAEGIIQELRQLRKAQLANVKDHELIEAKSRLEGAAPELVKKQKVNVKNTSPKQQLRAGDEVKVLTFGQKGQLLEKVSDTEWSVQIGILKMKVKESNMEYINTPKQTEKKAVATVKGRDYHVSLELDLRGERFENAMARVEKYLDDAQLASYPRVSIIHGKGTGALRQGVQDYLKKHRGVKTFRYGDMGEGGLGVTVVELK
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: S35B3_MOUSE
Sequence: MDLKFNNSRKYVSISVPSKTQAMSPHIKSVEDVVVLGVNLSKFSKLTQFLICVAGVFVFYLIYGYLQELIFSVEGFKPYGWYLTLVQFAFYSVFGLIELQLTQDRRRRIPGKTYMLIAFLTVGTMGLSNTSLGYLNYPTQVIFKCCKLIPVMLGGVFIQGKRYNLADVSAAVCMSLGLIWFTLADSTIAPNFNLTGVMLISLALCADAVIGNVQEKAMKLHNASNSEMVLYSYSIGFVYILLGLSCTSGLGPAVAFCSKNPVGTYGYAFLFSLTGYFGISFVLALIKIFGALLAVTVTTGRKAMTVVLSFLFFAKPFTFQYIWSGLLVVLGIFLNVYSKNMDKIRLPSVYNMIKKAMDMKKSRTLAQTV
What is the function of this protein?
Mediates the transport of adenosine 3'-phospho 5'-phosphosulfate (PAPS), from cytosol into Golgi.  PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi.  Compensates for the insufficient expression of SLC35B2/PAPST1 during the synthesis of sulfated glycoconjugates in the colon (By similarity).
What are the official names of this protein?
Adenosine 3'-phospho 5'-phosphosulfate transporter 2, PAPS transporter 2, Solute carrier family 35 member B3.
What is the protein family that this protein belongs to?
Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: TRPA_ECO7I
Sequence: MERYESLFIRLKERHEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGVDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVTKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKAFVQPMKAATRS
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: ATG12_BOVIN
Sequence: MAEEQESALQLPPSTAPEAEVPTEVSPETATPEPPSSAAVSPGTEEPVGDTKKKIDILLKAVGDTPIMKTKKWAVERTRTIQGLFDFIKKFLKLVASEQLFIYVNQSFAPSPDQEVGTLYECFGSDGKLVLHYCKSQAWG
What is the function of this protein?
Ubiquitin-like protein involved in autophagy vesicles formation.  Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function.  The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes.  The ATG12-ATG5 conjugate also regulates negatively the innate antiviral immune response by blocking the type I IFN production pathway through direct association with RARRES3 and MAVS.  Also plays a role in translation or delivery of incoming viral RNA to the translation apparatus (By similarity).
What are the official names of this protein?
Ubiquitin-like protein ATG12, Autophagy-related protein 12, APG12-like.
What is the protein family that this protein belongs to?
Belongs to the ATG12 family.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein. Note=TECPR1 recruits the ATG12-ATG5 conjugate to the autolysosomal membrane.
Protein: MNHD2_STAS1
Sequence: MLMSNLLILPLLLPAVCALGLVFIRTHSRLSRIFSIGTMAVTTVVSLLLLIYVMYHKPIALDFGGWQAPFGIQFVGDSLSLLLVTTSSFVVTLIMAYGFGRTEKRAIRYYLPSFILFLTVGVIGSFLTADLFNIYVMFEVMLLASFVLITLGQSVEQLRAAIIYVVLNILGSWLLLLGVGLLYKLTGTLNFTLVAQRLNEMDDKSSIVIVSMVFLIAFSAKAALVLFMWLPKAYAVLNTELAALFAALMTKVGAYALIRFFTLIFDEHSGITHPLLVFLSCITMLIGAFGVLAYRDIKKIAAYQVILSIGFIILGLGTNTIAGVNGAIFYLANDIVVKTLLFFIIGSLVYITGLRQYKSLYGLAKQEPFFGVAFVVMILAIGGVPPFSGFPGKVFIFKGAIENGNYIGLALMIITSLIAMFSLFRIFFVMYLGNENKGEAIVFNKIPTYRKNLIGVLVAMIIVMGLAAPLLFKVTDNATHLNMDDGLYEKMVNPHLIKGDK
What are the official names of this protein?
Putative antiporter subunit mnhD2, Mrp complex subunit D2, Putative NADH-ubiquinone oxidoreductase subunit mnhD2.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS9_NEIMB
Sequence: MNGKYYYGTGRRKSSVARVFLIKGTGQIIVNGRPVDEFFARETSRMVVRQPLVLTENAESFDIKVNVVGGGETGQSGAIRHGITRALIDFDAALKPALSQAGFVTRDAREVERKKPGLRKARRAKQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: RL4_STRPI
Sequence: MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASLRQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLPQKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGNEFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: CYNS_PHOLL
Sequence: MTQSQYSQTPRLALTDAIIDAKARKNLTFEDIAQGTGLSLAFVTAALLGQHPLPADAARVVVDRLELEEDAFFLLQTIPVRGSIPGGIPTDPTIYRFYEMVQVYGSTLKALVHEQFGDGIISAIDFKLDIKKVDDPNGGSRAVITLDGKYLPTKPF
What is the function of this protein?
Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
What are the official names of this protein?
Cyanate hydratase, Cyanase, Cyanate hydrolase, Cyanate lyase.
What is the protein family that this protein belongs to?
Belongs to the cyanase family.