PharMolix/UniProtQA huggingface dataset:
Protein: NDUA8_PANTR
Sequence: MPGIVELPTLEELKVDEVKISSAVLKAAAHHYGAQCDKPNKEFMLCRWEEKDPRRCLEEGKLVNKCALDFFRQIKRHCAEPFTEYWTCIDYTGQQLFRHCRKQQAKFDECVLDKLGWVRPDLGELSKVTKVKTDRPLPENPYHSRPRPDPSPEIEGDLQPATHGSRFYFWTK
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8, Complex I-19kD, CI-19kD, NADH-ubiquinone oxidoreductase 19 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFA8 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein. Mitochondrion intermembrane space. Mitochondrion.
Protein: CLPX_ALIFM
Sequence: MTDKRKDENSGKLLYCSFCGKSQHEVRKLIAGPSVYVCDECVDLCNDIIREELKDNTLSPKESSEELPTPRNIREHLDDYVIGQEHAKKVLAVAVYNHYKRLRNGDTTKDGVELGKSNILLIGPTGSGKTLLAETLARFLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDPAKAERGIVYIDEIDKISRKSENPSITRDVSGEGVQQALLKLIEGTIASVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVIEQRVATGTGIGFGADVRSKDNEATIGDLFKQIEPEDLVKFGLIPEFIGRLPVTTTLTELDEEALVQILSQPKNALTKQYGALFDLEGAELEFREDALKAIAKKAMDRKTGARGLRSILEAVLLETMYELPSKEGVSKVVIDESVINGESEPLLIFENTETKAISAE
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: YMSA_RHIML
Sequence: MAAPRQIAFYGKGGTGKPKRKPEPVTASKEDRCLGSPSKNKAHFHSRMNVMARMRGGHGFRVPSAASRKAMKHKWKGQPLPKKALILLEGTKMGTGQPPVAS
What is the function of this protein?
This protein is either not expressed, expressed at low levels or rapidly degraded.
What are the official names of this protein?
Uncharacterized protein in mosA 5'region, ORF1.
What is the protein family that this protein belongs to?
To the N-terminal of nitrogenase iron protein (NifH). Has lost the ATP-binding site.
Protein: GSA_ALIF1
Sequence: MTKSAELFAKAQDKIPGGVNSPVRAFAGVGGSPIFVERADGPLIFDADGKAYIDYVGSWGPMILGHNHAAIREAVISAAQRGLSFGAPTETEITMAELVSELVPSMEQVRMVSSGTEATMSAIRLARGYTGRDKIMKFEGCYHGHADSLLVKAGSGALTLGQPSSPGVPADFAKYTLTATFNDLDSVRELFAVNKGEIACIIVEPVAGNMNCIPPVEGFHEGLRQICDEEGALLIFDEVMTGFRVAENCAQGYYNIKPDLTTLGKVIGGGMPVGAFGGRKEVMQYIAPTGPVYQAGTLSGNPVAMAAGFACLKVLTEEGNEKRLADTTRHLANGFKELANKHGIPMVVNQVGGMFGFFFTDQETVTSYADVAKCDIERFKRFFHLMLKKGVYLAPSAFEASFTSLAHGPKEIEATLEAADQCFAIIASEAK
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRDXL_DICDI
Sequence: MSRIQQVNKSILIRSFCTGAPSKSNFSPVGNFLRIGDVVPDFSQDSSVGQINLYKTLGDSWGLFVSHPKDFTPICTTELGRLAKLKPEFEKRNCKILALSVDSVKDHLEWMKDIEETQKVKINYPIIADQDRKVADLYGMIHPNADNTFTVRSVFFISPDKRLRAQITLPASTGRNFNEIIRILDSFQLTDKYKVATPADWVDGDDCIIVPTVFDEDAKKLFPKGFPKIKSYLRVTPQPNK
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
1-Cys peroxiredoxin, Thiol-specific antioxidant, Thioredoxin peroxidase, Thioredoxin-dependent peroxiredoxin.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. Prx6 subfamily.
Protein: RL11_SACD2
Sequence: MAKKVEAYIKLQVAAGKANPSPPVGPALGQKGVNIMEFCKAFNAQTQGMEPGSPVPVVISVYSDRSFTFTMKTPPASFLLKKAAGLKSGSARPNTQKVGKVTRAQLEEIATIKMADLTAGDMDAAVRTIAGSARAMGLETEGV
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: UBIE_ECO81
Sequence: MVDKSQETTHFGFQTVAKEQKADMVAHVFHSVASKYDVMNDLMSFGIHRLWKRFTIDCSGVRRGQTVLDLAGGTGDLTAKFSRLVGETGKVVLADINESMLKMGREKLRNIGVIGNVEYVQANAEALPFPDNTFDCITISFGLRNVTDKDKALRSMYRVLKPGGRLLVLEFSKPIIEPLSKAYDAYSFHVLPRIGSLVANDADSYRYLAESIRMHPDQDTLKTMMQDAGFESVDYYNLTAGVVALHRGYKF
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: EREMS_SORC5
Sequence: MSSDRTSVVVSKRDAGGFEYPFAASCHPGREVTEQRTLAWVRRLRLVPDGRSLSRLKATNFSHLAAWLLPSASTQTLQLASDFTAVLFLLDDAYDEGQLSTDPESVEWLNEKYLGELFGYTEADMSDPLTRGMLDVRERIRRSHPHFFLNRWLSHFQYYYEANLWEANNRKQMRVPHLEEYLMMRRYSGAVYTYCDLLELLLERPLPLEVVQHPLIQTVRDICNDILCWTNDYFSLGKELTNGETHNLIVVLRNECVSTLEEAIDRLKDMHDRRVAEYQGVKEKVLALWADDEIRLYLDAVEAMIAGNQRWALEAGRYSGLESLIVRAG
What is the function of this protein?
Catalyzes the conversion of (2E,6E)-farnesyl diphosphate (FPP) to yield the bicyclic sesquiterpene eremophilene via a 1,10-cyclization, which requires the abstraction of the pyrophosphate from FPP to yield the (E,E)-germacradienyl cation.  The only accepted substrate is farnesyl diphosphate (FPP).
What are the official names of this protein?
(+)-eremophilene synthase, Sesquiterpene cyclase, Terpene synthase, Type I terpene cyclase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: BGAL_BIFB1
Sequence: MSKRRKHSWPQPLKGAESRLWYGGDYNPDQWPEEVWDDDIRLMKKAGVNLVSVGIFSWAKIEPEEGKYDFDWLDRAIDKLGKAGIAVDLASATASPPMWLTQAHPEVLWKDERGDTVWPGAREHWRPTSPVFREYALNLCRRMAEHYKGNPYVVAWHVSNEYGCHNRFDYSDDAMRAFQKWCKKRYKTIDAVNEAWGTAFWAQHMNDFSEIIPPRYIGDGNFMNPGKLLDYKRFSSDALKELYIAERDVLESITPGLPLTTNFMVSAGGSMLDYDDWGAEVDFVSNDHYFTPGEAHFDEVAYAASLMDGISRKEPWFQMEHSTSAVNWRPINYRAEPGSVVRDSLAQVAMGADAICYFQWRQSKAGAEKWHSSMVPHAGEDSQIFRDVCELGADLGRLSDEGLMGTKTVKSKVAVVFDYESQWATEYTANPTQQVDHWTEPLDWFRALADNGITADVVPVRSDWDSYEIAVLPCVYLLSEETSRRVREFVANGGKLFVTYYTGLSDENDHIWLGGYPGSIRDVVGVRVEEFAPMGNDMPGALDHLDLDNGTVAHDFADVITSTADTSTVLASYKAERWTGMNEVPAIVANGYGDGRTVYVGCRLGRQGLAKSLPAMLGSMGLSDLAGDGRVLRVERADAAAANHFEFVFNRTHEPVTVDVEGEAIAASLAHVDDGRATIDPTGVVVLRR
What are the official names of this protein?
Beta-galactosidase BbgII, Beta-gal.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 42 family.
Protein: BIOB_ECODH
Sequence: MAHRPRWTLSQVTELFEKPLLDLLFEAQQVHRQHFDPRQVQVSTLLSIKTGACPEDCKYCPQSSRYKTGLEAERLMEVEQVLESARKAKAAGSTRFCMGAAWKNPHERDMPYLEQMVQGVKAMGLEACMTLGTLSESQAQRLANAGLDYYNHNLDTSPEFYGNIITTRTYQERLDTLEKVRDAGIKVCSGGIVGLGETVKDRAGLLLQLANLPTPPESVPINMLVKVKGTPLADNDDVDAFDFIRTIAVARIMMPTSYVRLSAGREQMNEQTQAMCFMAGANSIFYGCKLLTTPNPEEDKDLQLFRKLGLNPQQTAVLAGDNEQQQRLEQALMTPDTDEYYNAAAL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: TAMB_CITRI
Sequence: MSLWKKISLGVLIFILLLLATVGFLVGTTTGLHLVFSAANRWVPGLEIGQVTGGWRDLSLKNIRYDQPGVAVNAGEVHLAVGLECLWKSSLCVNDLSLKDINVVIDSKKMPPGEQVEEEEESGPLNLSTPYPVTLSRVALENINVKIDDTTVSVMDFTSGLNWQEKNLTLKPTALQGLLIALPKVAEVAQEEVVEPKIQNPQPDEKPLGETLQDLFSKPVLPEMTDVHLPLNLNIEEFKGEQLRLTGDTDLTVFSLLLKVSSIDGNMKLDALDIDSSQGAVNATGTAQLANNWPVDITLNSTLNVEPLKGEKIKLKVGGALREQLEVGVNLSGPLDVNLRAQARLAEAGLPLNLEVVSEQISWPFTGDRQFQADNTRLKLTGKMTDYTLSMRTAVKGQDVPPATITLDAKGNEQQINLDKLTVAALEGKTELKALVDWRQAISWRGELTLDGINTAKEVPDWPSKLNGLIKTRGSLYGGSWQMEVPELKLTGNVKQNKVNVNGSLKGNSYMQWTIPGLHLVLGPNSADVKGELGVKDLNLDATIDAPGLDNALPGLGGTAKGLVKVRGTVDAPQLLADITARGLRWQELSIAQVRVDGDIKSTDQIAGKLDVRVERISQPDVNINLVTLHAKGSEKQHELQLRIQGEPVSGQLDLAGSFDREEMRWKGTLSNTRFRTPVGPWSQTRAIALDYRGQEQKISIGPHCWTNPNAELCVPQTIDAGAEGRAVVNLNRFDLAMLKPFMPETTQASGVFSGKADVAWDTTKEGLPQGNVTLSGRSVKVTQTVNDAPLPLAFDTLNVSADLHDNRAELGWQIRLSNNGQLDGQVQVTDPQGRRNLGGNVSIRNLNLAMVNPIFARGEKAAGLLNANLRLGGDVQSPQMFGQLQLNGVDIDGNFMPFDMQPSQLAMNFNGTRSTLTGVVRTQQGEINLSGDADWSQIENWRARIAAKGSRVRITVPPMVRLDVSPDVVFEATPSLFTLDGRVDVPWARIVVHELPESAVGVSSDEVMLNNQLQPEEPQTAAIPINSNLIVHVGNNVRMDAFGLRARLTGDLKVAQDKQGLGLNGQINIPEGRFHAYGQDLLVRKGELLFSGPPDQPILNIEAIRNPEATEDDVIAGVRVTGSADEPKAEIFSDPAMSQQEALSYLLRGQGLDSNQSDSAAMTSMLIGLGVAQSGQVVGKIGETFGVSNLALDTQGVGDSSQVVVSGYVLPGLQVKYGVGIFDSLATLTLRYRLMPKLYLEAVSGVDQALDLLYQFEF
What is the function of this protein?
Part of the translocation and assembly module (TAM) autotransporter assembly complex, which functions in translocation of autotransporters across the outer membrane (PubMed:22466966).  Substrate binding to TamA moves its POTRA domains about 30 Angstroms into the periplasm, which would deform either the outer membrane or TamB and may provide force to reset TAM (By similarity).
What are the official names of this protein?
Translocation and assembly module subunit TamB, Autotransporter assembly factor TamB.
What is the protein family that this protein belongs to?
Belongs to the TamB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: CH60_CALBD
Sequence: MAAKMILFDEEARRALERGVNKLADTVKVTLGPKGRNVVLEKKFGSPQIVNDGVTIAKEIELEDPFENMGAQIVREVASKTNDIAGDGTTTATVLAQAMIREGLKNIAAGANPMILRKGIQKAVDVVVEEIRKMSKKVRGKEDITYVASISAGDEEIGKLVADAMEKVTNDGVITVEESKTTETTLEIVEGMQFDRGYISAYMVTDTERMEAVLDDPYILITDKKISTIQDILPLLEQIVQQGRKLLIIAEDVEGEALATLVVNKLRGTLQCVAVKAPGFGDRRKAMLQDIAILTGGQVISEELGLDLREVKLSQLGRARQVKVQKENTIIVDGAGDPSEIKARIQSIKKQIEETTSDFDREKLQERLAKLAGGVAVIHVGAATETELKEKKLRIEDALAATKAAVEEGIVPGGGTALINAIPALDKLIESLTGDEKTGAMIVRKALEEPLRQIAENAGLDGSVIVNKVKESPAGVGFDALNERFVDMFEAGIVDPTKVTRTAIQNAASAAAMLLTTEAVVAEKPEKEKNPPAPAPDMY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPS_WIGBR
Sequence: MAIIGIGIDIVNLERINKIILCYGNKFVKKILSFNEKKKYYELKNKKKNISVNFLAKRLAAKEAASKAFGLGMKKGLYFSQFEVLNNNLGKPYFKFNNTAKNLIKALNITNIHLSLTDERKYACATVIFEDNRTNIILS
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSB_SHIFL
Sequence: MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNDDVAALQATNAKLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNNR
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: RL3_PYRNV
Sequence: MGLKINRPRRGSMGVYPRKRAADIVPRVRTWPEVNLGKPALLGFAAYKAGMLHAVVVEDRPTSPLYGKEVVRPVTVLDAPPLFIWGFRLYTLDPTNGYRRSIAEVWAPELPAYIRRVLTLPEKADVDKQMKKVEEFKDVAVDVRALVATQPHLSGIGKKTPELLEIPIGGVPSVDERIKFAVSLLGKTVSPKEVFTAGQLVDVIAVTKGKGYQGVIKRFGVTILPRWHKHRKGHRRTGTIGPQAPALMFTQPRPGQMGFHQRTEYNKRVVKIGDNGAEITPKSGFLHYGVIRGPYILIQGTVPGAKKRLVVLRHPARPPKKAPPAAEPQVVWLSSQSI
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: RNPH_HYDS0
Sequence: MRKNNRKLDELRPIRIQRDFNIHAEGSCLVEFGNTRVICTASIAESVPPFLKGKNQGWITAEYSMLPRATATRNMRESVTGKIGGRTHEIQRMIGRAMRAVIDLTKIGERTIWIDCDVIQADGGTRTASIVGAFIAMTDAIIKLNEQKLINSVPIRDTVGAVSVGIVNDRLMLDLDFEEDSNAAVDMTIVATGNGEMVEIHSLGEEATYTRKEFEAMLDLGLESLKQIAELQNVFYEKMPSINLWKRKSVKEAKL
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: RL19_SHEB9
Sequence: MNNIIKMLNDEQMKQDVPAFGAGDTVVVQVRVKEGDKERLQAFEGVVIAKRNRGLHSAFTVRKISNGEGVERAFQTHSPLIASIEVKRRGRVRRAKLYYLRDRSGKSARIREKLATK
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: FDHE_SHEB9
Sequence: MSHTAEIPLVPGSESPLELKPLKAADPQIVYHRRAHRLLSLAKDSPLADYFELCRRLVSIQAKLAEGADFGQLLAWGKDEATPLSLLGSEADSYWQGLLQQLLSDLLPQVDESIARVVRLLMQQSPEQLSSWGRSLRQGHVSEVPAHFSLFIWAAMGVYWSHWAPMVIKRMDQRKVAQQSMCPVCGCHPVASVIVDQPRAGLRYLHCSLCESEWHYIRAHCTSCGQDKEMTIWSLDDAQAQVRIESCDECHGYTKMMFVENSPSMDVAADDLATLMLDSELNAKGFGATTLNPLLMAHETT
What is the function of this protein?
Necessary for formate dehydrogenase activity.
What are the official names of this protein?
Protein FdhE homolog.
What is the protein family that this protein belongs to?
Belongs to the FdhE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G3P_MYCLE
Sequence: MTVRVGINGFGRIGRNFYRALLAQQEHGIADVQVVAINDITDNSTLAYLLKFDSILGRLPHDVSLEEEDTIVVGSEKIKALAVREGPAALPWHAFGVDVVVESTGLFTNAAKAKGHLEAGAKKVIVSAPATDPDITIVFGVNDDKYDGSQNIISNASCTTNCLAPLAKVLHDQFGIVKGLMTTVHAYTQDQNLQDGPHSDLRRARAAALNVVPTSTGAAKAIGLVMPELKGKLDGYALRVPIPTGSVTDLTADLSKCVSVNEINAVFQDAAEGRLKGILKYVDAPIVSSDIVTDPHSSIFDSGLTKVIASQAKVVSWYDNEWGYSNRLVDLVGLVGKSL
What is the function of this protein?
Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD.  The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH.  The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, NAD-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_NITSB
Sequence: MIQSFTRLNVADNSGAKEIMAIKVLGGSKRRYASVGDVIVASVKKALPNGKVKKGQVVKAVVVRTKKEIQRENGSLIRFDDNAAVILDNKNEPIGTRIFGPVAREVRYKNFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: HEM1_ALKMQ
Sequence: MKIIVFGITHKKATIDLREKVAFSQSKKQEAYSLLKESPFIHEAVILSTCNRSEVFAVVQDTSIARRWFKRFYTDFFQLKETALEGCNHFEKGREAVQYLYHVCVGVDSLVIGEDQILGQVKEAHAEALDFAATGKILNKLFLEAVTTAKEVKTETAISENALSISSIAVKQMENHLKGLVGKTVLVVGFGKMSRIAIENLLCKGIKRLYICNRTKESVQELIEKHPQIHYLSYDQKYEMLNGVDAVISATGAPHFIFYKEDMEKIYQKHRPMCMIDIALPRDIDPAVKEIEGIELFHIDDLKEIANENLAYRMDCIEIIKQSINEAIEKYEGWYQCLPIYPRIQAIKAYSETLTDQELEKLFKRLDHMAEEDRQVIEVVVKSLVKKMWKTPILQLKDAGIRGNGEAFAAFVDEFLGLDAGCGK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: CP17A_BOVIN
Sequence: MWLLLAVFLLTLAYLFWPKTKHSGAKYPRSLPSLPLVGSLPFLPRRGQQHKNFFKLQEKYGPIYSFRLGSKTTVMIGHHQLAREVLLKKGKEFSGRPKVATLDILSDNQKGIAFADHGAHWQLHRKLALNAFALFKDGNLKLEKIINQEANVLCDFLATQHGEAIDLSEPLSLAVTNIISFICFNFSFKNEDPALKAIQNVNDGILEVLSKEVLLDIFPVLKIFPSKAMEKMKGCVQTRNELLNEILEKCQENFSSDSITNLLHILIQAKVNADNNNAGPDQDSKLLSNRHMLATIGDIFGAGVETTTSVIKWIVAYLLHHPSLKKRIQDDIDQIIGFNRTPTISDRNRLVLLEATIREVLRIRPVAPTLIPHKAVIDSSIGDLTIDKGTDVVVNLWALHHSEKEWQHPDLFMPERFLDPTGTQLISPSLSYLPFGAGPRSCVGEMLARQELFLFMSRLLQRFNLEIPDDGKLPSLEGHASLVLQIKPFKVKIEVRQAWKEAQAEGSTP
What is the function of this protein?
A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis.  Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways.  A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage.  The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol.  Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, dehydroepiandrosterone (DHEA) and androstenedione.  Has 16-alpha hydroxylase activity.  Catalyzes 16-alpha hydroxylation of 17-alpha hydroxy pregnenolone, followed by the cleavage of the C17-C20 bond to form 16-alpha-hydroxy DHEA.  Also 16-alpha hydroxylates androgens, relevant for estriol synthesis.  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).
What are the official names of this protein?
Steroid 17-alpha-hydroxylase/17,20 lyase, 17-alpha-hydroxyprogesterone aldolase, CYPXVII, Cytochrome P450 17A1, Cytochrome P450-C17, Cytochrome P450c17, Steroid 17-alpha-monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane. Microsome membrane.
Protein: NRDR_PSEPG
Sequence: MHCPFCGANDTKVIDSRLVAEGEQVRRRRECVACGERFTTFETAELVLPRLIKQDGTRQPFDEEKLRAGMQRALEKRPVSVERLEAALAHIKSRLRATGEREVKSLVVGEMVMAELRKLDEVAYIRFASVYRRFQDLDEFREEIDRLAREPARE
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: RS19_GEMAT
Sequence: MSRSIKKGPFVAERLEAKVVTMNAKSEKKVVKTWSRASTILPEFVGHTFAVHNGNKFIPVYVTENMVGHKLGEFSPTRLFRGHAGQKADVKKKGGK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: OVAL_COTJA
Sequence: MGSIGAASMEFCFDVFKELKVHHANDNMLYSPFAILSTLAMVFLGAKDSTRTQINKVVHFDKLPGFGDSIEAQCGTSVNVHSSLRDILNQITKQNDAYSFSLASRLYAQETYTVVPEYLQCVKELYRGGLESVNFQTAADQARGLINAWVESQTNGIIRNILQPSSVDSQTAMVLVNAIAFKGLWEKAFKAEDTQTIPFRVTEQESKPVQMMYQIGSFKVASMASEKMKILELPFASGTMSMLVLLPDDVSGLEQLESIISFEKLTEWTSSSIMEERKVKVYLPRMKMEEKYNLTSLLMAMGITDLFSSSANLSGISSVGSLKISQAVHAAHAEINEAGRDVVGSAEAGVDATEEFRADHPFLFCVKHIETNAILLFGRCVSP
What is the function of this protein?
Storage protein of egg white.  Lack protease inhibitory activity (By similarity).
What are the official names of this protein?
Ovalbumin, Egg albumin.
What is the protein family that this protein belongs to?
Belongs to the serpin family. Ov-serpin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NADE_LATSS
Sequence: MNALQAEIIAALKTQPTIDPAKEIRRSVDFMKAYLKKNTFLKSYVLGISGGQDSTLVGALTEKAMQEMRAETGDESYQFIAVRLPYGEQADESDAMAAIEFMAADQVKRVNIKGSVDAMVQSLAETGVTVSDFNKGNIKARVRMIAQYGIAGENSGAVLGTDHSAESITGFYTKFGDGGADLVPIFRLNKRQGKAMLAELGAPKHLYEKVPTADLEEDRPALPDELALGVTYDQIDDYLEGRQVSEEAATKIENWHKKTAHKRHLPITIYDTFWQ
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: PYRD_SALA4
Sequence: MYYPFVRKALFQLDPERAHEFTFQQLRRITGTPLEALVRQKVPTKPVTCMGLTFKNPLGLAAGLDKDGECIDALGAMGFGSLEIGTVTPRPQPGNDKPRLFRLVDAEGLINRMGFNNLGVDNLVENVKKAHFDGILGINIGKNKDTPVENGKDDYLICMEKVYAYAGYIAINISSPNTPGLRTLQYGDALDDLLTAIKNKQNDLQAIHHKYVPVAVKIAPDLCEEELIQVADSLLRHNIDGVIATNTTLDRSLVQGMKNCQQTGGLSGRPLQLKSTEIIRRLSQELKGQLPIIGVGGIDSVIAAREKIAAGATLVQIYSGFIFKGPPLIKEIVTHI
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RPOZ_STRZP
Sequence: MLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSEKSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGEKI
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: RS17_MYCUA
Sequence: MMAEAKTGAKATKSAAAGAADGASKEKGPKHTPSPPKPSGRRKTRIGYVVSDKMQKTIVVELEDRVRHPLYGKIIRTTKKVKVHDEHSAAGIGDRVSLMETRPLSATKRWRLVEILEKAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.