PharMolix/UniProtQA huggingface dataset:
Protein: T185B_MOUSE
Sequence: MNPRGLFQDFNPSKFLIYACLLLFSVLLPLRLDGIIQWSYWAVFAPIWLWKLLVIVGASVGAGVWARNPRYRTEGEACVEFKAMLIAVGIHLLLLMFEILVCDRVERGTHFWLLVFMPLFFVSPVSVAACVWGFRHDRSLELEILCSVNILQFIFIALRLDRIIHWPWLVVFVPLWILMSFLCLVVLYYIVWSLLFLRSLDVVAEQRRTHVTMAISWITIVVPLLIFEVLLVHRLDDHNTFSYISIFIPLWLSLLTLMATTFRRKGGNHWWFGIRRDFCQFLLEVFPFLREYGNISYDLHHEDSEDAEDASVSEAPKIAPMFGKKARVVITQSPGKYVPPPPKLNIDMPD
What are the official names of this protein?
Transmembrane protein 185B, Erythropoietin-induced EST 3-2, Protein FAM11B.
What is the protein family that this protein belongs to?
Belongs to the TMEM185 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ERA_STAA2
Sequence: MTEHKSGFVSIIGRPNVGKSTFVNRVIGHKIAIMSDKAQTTRNKIQGVMTRDDAQIIFIDTPGIHKPKHKLGDYMMKVAKNTLSEIDAIMFMVNANEEIGRGDEYIIEMLKNVKTPVFLVLNKIDLVHPDELMPKIEEYQSYMDFTEIVPISALEGLNVDHFIDVLKTYLPEGPKYYPDDQISDHPEQFVVGEIIREKILHLTSEEIPHAIGVNVDRMVKESEDRVHIEATIYVERDSQKGIVIGKGGKKLKEVGKRARRDIEMLLGSKVYLELWVKVQRDWRNKVNFIRQIGYVEDQD
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: IGHG1_RAT
Sequence: AETTAPSVYPLAPGTALKSNSMVTLGCLVKGYFPEPVTVTWNSGALSSGVHTFPAVLQSGLYTLTSSVTVPSSTWPSQTVTCNVAHPASSTKVDKKIVPRNCGGDCKPCICTGSEVSSVFIFPPKPKDVLTITLTPKVTCVVVDISQDDPEVHFSWFVDDVEVHTAQTRPPEEQFNSTFRSVSELPILHQDWLNGRTFRCKVTSAAFPSPIEKTISKPEGRTQVPHVYTMSPTKEEMTQNEVSITCMVKGFYPPDIYVEWQMNGQPQENYKNTPPTMDTDGSYFLYSKLNVKKEKWQQGNTFTCSVLHEGLHNHHTEKSLSHSPGK
What are the official names of this protein?
Ig gamma-1 chain C region.
Protein: UBIA_ESCF3
Sequence: MEWSLTQNKLLAFHRLMRTDKPIGALLLLWPTLWALWVATPGVPPLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRPLPSGAVTEKEARTLFVVLVLLAFLLVLTLNTMTILLSVAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAVSESVPLSCWLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKFIIGVLQIGVMVLMALIGWLNGLDWGYYWSILVAGGLFVYQQKLIANREREACFKAFMNNNYVGLVLFLGLAMSYWHF
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: THLA_STAAB
Sequence: MTRVVLAAAYRTPIGVFGGAFKDVPAYDLGATLIEHIIKETGLNPSEINEVIIGNVLQAGQGQNPARIAAMKGGLPETVPVFTVNKVCGSGLKSIQLAYQSIVTGENDIVLAGGMENMSQSPMLVNNSRFGFKMGHQSMVDSMVYDGLTDVFNQYHMGITAENLVEQYGISREEQDTFAVNSQKKAANAQQNGGFDSEIVPVSIPQRKGEPIVVTKDEGVRENVSVEKLSRLRPAFKKDGTVTAGNASGINDGAAMMLVMSEDKAKELNIEPLAVLDGFGSHGVDPSIMGIAPVGAVEKALKRSKKELSDIDVFELNEAFAAQSLAVDRELKLPPEKVNVKGGAIALGHPIGASGARVLVTLLHQLNDEVETGLTSLCIGGGQAIAAVVSKYK
What are the official names of this protein?
Probable acetyl-CoA acyltransferase, Acetoacetyl-CoA thiolase.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAVA_YERP3
Sequence: MAQSSQLAERISRLSHALESGLYERQEAIRLCLLAALSGESVFLLGPPGIAKSLIARRLKFAFRHARAFEYLMTRFSTPEEVFGPLSIQALKEEGRYQRMTGGYLPEAEIVFLDEIWKAGPAILNTLLTAINERRFRNGDREDSIPMRLLVTASNELPDADSSLEALYDRMLIRLWLDRVQEKQNFRSLLISRQNENHNPVAENLSITDEEFHQWQPLIDKITLPDHCFELIFQLRQRLSALEHAPYVSDRRWKKALRLLQASAFFSGRDEITPIDLILLKDCLWHDLNSFKLLQQQLEQLLTEQGYQQQSLLMKLQDINSKWLQHQQQQSDHQALTVVKQSGMFSRKAQYALPDNLTDSTLTLLLQKPLNLHDIQVNHLQVDKEALAQWLNKGGALRAKLNGVGYAQSIDAEIDDQLHIIILDVSRQPSTLSLPGATTTSVPPELLLALTKLESTLAEQRRLFSQHQPCLFTPSSWLAKIEASLLQVVEQLQFQQIQFQQRQFQQQKHSGH
What is the function of this protein?
Functions as an ATPase.  May play a role in metal insertion (metal-chelatase) or as a chaperone.
What are the official names of this protein?
ATPase RavA, Regulatory ATPase variant A.
What is the protein family that this protein belongs to?
Belongs to the RavA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_PSYWF
Sequence: MTKPNADSLMKIGQLKKPYGIKGWLWVFSETEEREAIFSYSPWWMKTATGFKPLTVTQWRRQGTGIVAQFEQVPDRNVAETMNGVSIWIDKDSLPSTEEDEYYWSDLVGLSVINKQDECLGTVKELFETGAHPIMKVVPSQDSIDDEPRMIPWHKQTVDVVDLAAGRMVVDWERDF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T11X1_HUMAN
Sequence: MPKTEETVLQNDPSVAENGAPEPKTPGQSQKSKSFCLDDQSPDLIETVNEVSKLSISHEIVVNQDFYVEETILPPNSVEGRFAEAMYNAFWNHLKEQLLSTPPDFTCALELLKDVKETLLSLLLPWQNRLRNEIEEALDTDLLKQEAEHGALDVPHLSNYILNLMALLCAPVRDEAIQKLETIRDPVQLLRGILRVLGLMKMDMVNYTIQSFRPYLQEHSIQYEQAKFQELLDKQPSLLDYTTKWLTKAATDITTLCPSSPDSPSSSCSMACSLPSGADSADGQNPAPGTGIPVAPVNCPGLSLASGQKLLW
What are the official names of this protein?
T-complex protein 11 X-linked protein 1.
What is the protein family that this protein belongs to?
Belongs to the TCP11 family.
Protein: NU4M_SHEEP
Sequence: MLKYIIPTMMLMPLTWLSKNSMIWINTTLHSLLISLTSLLLLNQFGDNSLNFSLTFFSDSLSTPLLILTMWLLPLMLMASQHHLSKENLARKKLFISMLILLQLFLIMTFTATELIFFYIMFEATLVPTLIIITRWGNQTERLNAGLYFLFYTLAGSLPLLVALIYIQNTMGSLNFLILQYWVQPMPNSWSNTFMWLACMMAFMVKMPLYGLHLWLPKAHVEAPIAGSMVLAAILLKLGGYGMMRITLLLNPITDFMAYPFIMLSLWGMIMTSSICLRQTDLKSLIAYSSVSHMALVIVAILIQTPWSYMGATALMIAHGLTSSMLFCLANSNYERVHSRTMILARGLQTLLPLMAAWWLLASLTNLALPPSINLIGELFVVMSTFSWSNITIILMGLNMVITALYSLYMLITTQRGKHTHHINNILPSFTRENALMSLHMLPLLLLSLNPKIILGPLY
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CPSM_LITCT
Sequence: MTRILSVFKTAKTGVLNAAAHRYRGFSKAGVRLMSVKAQTANLVLEDGTKIKGYSFGHPASVAGEVIFNTGLGGYVEAVTDPSYHGQILTLTNPIIGNGGAPDTKARDAYGLMKYIESENIQASGLLVLDYSHEYSHWGAVKSLSEWLHEEKVPALCGIDTRMLAKKIRDNKGAVLGKIEFEGQPVEFIDPNKRNLIAEVSTKETKVFGKGNPVRIVAVDCGVKHNIIRQLVKRGAEVHLVPWNHDFSQMEYDGLLITSGPGNPELAKPLIQNLKKVFQSDRPEPIFGICKGNEIAALAAGGKTYRLPMANRGQNQPVMITLNGQAFITAQNHAYAVDNNSLPAGWKPLFVNINDQSNEGIMHETKPIFTSQFHPEANPGPVDTEFLFDVYMSLIKKGKGTTLTSVMPKPALQSKRIDVAKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEKTDGIILGMGGQTALNCGVELFKRGVLKEYGVRVLGTSVESIMFTEDRQLFSDKLNEIKEPIAPSFAVESVKDALEAADKIGYPVMIRSAYALGGLGSGLCPDKETLTDLATKALAMTNQILVERSVVGWKEIEYEVVRDAADNCVTVCNMENVDAMGVHTGDSIVVAPCQTLSNEECQMLRAVSIKVVRHLGIVGECNIQFALHPTSLEYVIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTTACFEPSLDYMVTKIPRWDLDRFHGASGLIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSVDGFTSNLPMNKAWSSDVNLRKEMAEPTSTRMYSMAKAIQSGISLDEINKLTAIDKWFLYKMQGILNMEKTLKGSRSESVPEETLRRAKQIGFSDRYIGKCLGLSETQTRELRLNKNVKPWVKQIDTLAAEYPAITNYLYLTYNGQEHDIKFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRHVGKKTVVVNCNPETVSTDFDECDKLYFEELSQERIMDVFQLEQCDGCIISVGGQIPNNLAVPLYKNGVKIMGTSPMQIDRAEDRSIFSAVLDELQIAQAPWKAVNSLDDALQFTKTVGYPCLLRPSYVLSGSAMNVVYGEEELKTFLAEATRVSQEHPVVITKFIEGAREVEMDAVGKEGRVISHAISEHVEDAGVHSGDATLMIPTQSISQGAIEKVKIATKKIATAFAISGPFNVQFLVRGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGEKIDESSLPTLERPVIPADYVGIKAPMFSWPRLRGADPVLKCEMASTGEVACFGQNVYSAFLKAMISTGFKLPQKGILIGIQHSFRPHFLGTAQTLKDEGFKLYATEATADWLNANDITATPVAWPSQEGQSGPSSIYKLIKEGNIDMVINLPNNNTKYVRDNFAIRRTAVDTGTALLTNFQVVKMFAEAIKYSGDLDAKSLFHYRQFGGAKPS
What is the function of this protein?
Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell.
What are the official names of this protein?
Carbamoyl-phosphate synthase [ammonia], mitochondrial, Carbamoyl-phosphate synthetase I, CPSase I.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RRA1_ARATH
Sequence: MAVRKEKVQPFRECGIAIAVLVGIFIGCVCTILIPNDFVNFRSSKVASASCESPERVKMFKAEFAIISEKNGELRKQVSDLTEKVRLAEQKEVIKAGPFGTVTGLQTNPTVAPDESANPRLAKLLEKVAVNKEIIVVLANNNVKPMLEVQIASVKRVGIQNYLVVPLDDSLESFCKSNEVAYYKRDPDNAIDVVGKSRRSSDVSGLKFRVLREFLQLGYGVLLSDVDIVFLQNPFGHLYRDSDVESMSDGHDNNTAYGFNDVFDDPTMTRSRTVYTNRIWVFNSGFFYLRPTLPSIELLDRVTDTLSKSGGWDQAVFNQHLFYPSHPGYTGLYASKRVMDVYEFMNSRVLFKTVRKDEEMKKLKPVIIHMNYHSDKLERMQAAVEFYVNGKQDALDRFRDGS
What is the function of this protein?
Plays a role in the arabinosylation of cell wall components (PubMed:17401635).  Involved in the arabinosylation of extensin proteins in root hair cells.  Extensins are structural glycoproteins present in cell walls and its arabinosylation is important for root hair cell development (PubMed:21680836).
What are the official names of this protein?
Arabinosyltransferase RRA1, Protein REDUCED RESIDUAL ARABINOSE 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 77 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: LIMF_DICDI
Sequence: MSGQNILKCKKCQLEITNKIITNHNSDTFHEQCFVCKLCSTPISDPYFTDKETGDFYCAKCEVIRNDQSKPLRESLGFCSLCYKYFRQNEDILTIDLERYHIGCLKCTICKKGINNEKYYREKMTSKLSNYCCEDCFEKVDKCNGCNSMTLGQTLLAMGKNYHANCFKCFKCSEIIKPNSPYSINKQTNTPSCQKCN
What is the function of this protein?
Involved in the regulation of phagocytosis.  May repress ChLim and activate rab21.
What are the official names of this protein?
LIM domain-containing protein F.
Protein: ACNB_HELPY
Sequence: MKDFLEDYKKSVSERGSEGIPPLPLNAKQVQAVVEILTKDPTNAAFAKELLIHRVSPGVDEGAKVKAEFLAKLSQKKLECVHISALEATTLLGTMLGGYNVEPLIMGLESQDKNIAKESAKALKTTLLVYGSFDKIAAMSKTNALAKEVLESWANAEWFLNKEPLNECIEACVFKIDGETNTDDLSPASDAFTRSDIPLHAKAMLKNRIENYEQRIKAIKTKGVPVAYVGDVVGTGSSRKSATNSIMWHFGKDIPFVPNKRSGGIVIGGVIAPIFFATCEDSGALPIVADVKDLKEGDLIKIYPYKGEITLNDKVVSTFKLEPETLLDEVRASGRIPLIIGRGLTNKARKFLGLGESEAFKKPSAPKSDAKGYTLAQKIVGHACGVKGILPGTYCEPKVTTVGSQDTTGAMTRDEVKELASLKFDAPFVLQSFCHTAAYPKPSDVSLHATLPGFITQRGGVALHPGDGVIHTWLNRMGLPDTLGTGGDSHTRFPLGISFPAGSGLVAFAAVTGTMPLNMPESVLVRFKGEMNPGITLRDLVNAIPYYAIKKGLLTVEKKGKINVFNGRILEIEGLPDIKMEQAFELSDASAERSAAACVVRLNKEPMIEYLKSNIKLIDEMIASGYEDKETLKKRRDAMQAWVDNPVLLEPDSNAQYAAVIEIDVAEITEPILACPNDPDDVATLSEVLADTTGKRPHAIDEVFIGSCMTNIGHFRAFGEIVKNAPPSQARLWVVPPSKMDEQELINEGYYAIFGAAGARTEVPGCSLCMGNQARVRDNAVVFSTSTRNFDNRMGRGAKVYLGSAELGAACALLGRIPTKEEYMNLVSEKLESQKDKIYRYMNFNLMENFRL
What is the function of this protein?
Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably via the 2-methylcitrate cycle I (propionate degradation route).  Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate.  Catalyzes the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate.  The apo form of AcnB functions as a RNA-binding regulatory protein.
What are the official names of this protein?
Aconitate hydratase B, ACN, Aconitase, (2R,3S)-2-methylisocitrate dehydratase, (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase, 2-methyl-cis-aconitate hydratase, Iron-responsive protein-like, IRP-like, RNA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family.
Protein: BGLS_CALSA
Sequence: MDMSFPKGFLWGAATASYQIEGAWNEDGKGESIWDRFTHQKRNILYGHNGDVACDHYHRFEEDVSLMKELGLKAYRFSIAWTRIFPDGFGTVNQKGLEFYDRLINKLVENGIEPVVTLYHWDLPQKLQDIGGWANPEIVNYYFDYAMLVINRYKDKVKKWITFNEPYCIAFLGYFHGIHAPGIKDFKVAMDVVHSLMLSHFKVVKAVKENNIDVEVGITLNLTPVYLQTERLGYKVSEIEREMVSLSSQLDNQLFLDPVLKGSYPQKLLDYLVQKDLLDSQKALSMQQEVKENFIFPDFLGINYYTRAVRLYDENSSWIFPIRWEHPAGEYTEMGWEVFPQGLFDLLIWIKESYPQIPIYITENGAAYNDIVTEDGKVHDSKRIEYLKQHFEAARKAIENGVDLRGYFVWSLMDNFEWAMGYTKRFGIIYVDYETQKRIKKDSFYFYQQYIKENS
What are the official names of this protein?
Beta-glucosidase A, Amygdalase, Beta-D-glucoside glucohydrolase, Cellobiase, Gentiobiase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
Protein: CH602_SALAI
Sequence: MAKILSFSDDARHQLEHGVNALADAVKVTLGPRGRNVVLDKKFGAPTITNDGVTIAKEIELTNPYENLGAQLVKEVATKTNDVAGDGTTTATVLAQALVREGLRNVAAGANPTGLKRGIDAAATKVSEELLGKAVDVSDKAAIAHVATVSAQDSTIGELIAEAMERVGRDGVITVEEGSTLATELDVTEGLQFDKGFISPNFVTDAEGQESVLEDAYILITTQKISAIEELLPLLEKVLQESKPLLIIAEDVEGQALSTLVVNALRKTMKVCAVKAPGFGDRRKAMLQDMAILTGAELVAPELGYKLDQVGLEVLGTARRVVVDKENTTIVDGGGQASDAEDRVAQIRKEIEASDSEWDREKLAERLAKLSGGIAVIRAGAATEVEMKERKHRIEDAIAATKAAVEEGTVPGGGAALAQVLPALDGDLGLTGDEQVGVSIVRKALIEPLRWIAQNAGHDGYVVVQKVAGKDWGHGLDAATGEYVDLAKAGILDPVKVTRNAVANAASIAGLLLTTESLVVEKPQEPEPAAAGHGHGHGHQHGPGF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTBP_HUMAN
Sequence: MDRYLLLVIWGEGKFPSAASREAEHGPEVSSGEGTENQPDFTAANVYHLLKRSISASINPEDSTFPACSVGGIPGSKKWFFAVQAIYGFYQFCSSDWQEIHFDTEKDKIEDVLQTNIEECLGAVECFEEEDSNSRESLSLADLYEEAAENLHQLSDKLPAPGRAMVDIILLLSDKDPPKLKDYLPTVGALKHLREWYSAKITIAGNHCEINCQKIAEYLSANVVSLEDLRNVIDSKELWRGKIQIWERKFGFEISFPEFCLKGVTLKNFSTSNLNTDFLAKKIIPSKDKNILPKVFHYYGPALEFVQMIKLSDLPSCYMSDIEFELGLTNSTKQNSVLLLEQISSLCSKVGALFVLPCTISNILIPPPNQLSSRKWKEYIAKKPKTISVPDVEVKGECSSYYLLLQGNGNRRCKATLIHSANQINGSFALNLIHGKMKTKTEEAKLSFPFDLLSLPHFSGEQIVQREKQLANVQVLALEECLKRRKLAKQPETVSVAELKSLLVLTRKHFLDYFDAVIPKMILRKMDKIKTFNILNDFSPVEPNSSSLMETNPLEWPERHVLQNLETFEKTKQKMRTGSLPHSSEQLLGHKEGPRDSITLLDAKELLKYFTSDGLPIGDLQPLPIQKGEKTFVLTPELSPGKLQVLPFEKASVCHYHGIEYCLDDRKALERDGGFSELQSRLIRYETQTTCTRESFPVPTVLSPLPSPVVSSDPGSVPDGEVLQNELRTEVSRLKRRSKDLNCLYPRKRLVKSESSESLLSQTTGNSNHYHHHVTSRKPQTERSLPVTCPLVPIPSCETPKLATKTSSGQKSMHESKTSRQIKESRSQKHTRILKEVVTETLKKHSITETHECFTACSQRLFEISKFYLKDLKTSRGLFEEMKKTANNNAVQVIDWVLEKTSKK
What is the function of this protein?
Inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells (By similarity).  May play a role in MDM2-dependent p53/TP53 homeostasis in unstressed cells.  Inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability.  This promotes MDM2-mediated ubiquitination of p53/TP53 and its subsequent degradation.
What are the official names of this protein?
Mdm2-binding protein, hMTBP.
What is the protein family that this protein belongs to?
Belongs to the MTBP family.
Protein: DAPF_PSEAB
Sequence: MLLRFTKMHGLGNDFMVLDLVSQHAHVQPKHVKLWGDRNTGVGFDQLLIVEAPSSPDVDFRYRIFNADGSEVEQCGNGARCFARFVQDKRLTVKKSIRVETKGGIIELNIRPDGQVTVDMGPPRLAPAEIPFQAEREALSYEIEVNGQRVELAAVSMGNPHGVLRVENVDSAPVHSLGPQLEVHPRFPKKANIGFLQVLDPHHARLRVWERGVGETQACGTGACAAAVAGIRQGWLQSPVQIDLPGGRLHIEWAGPGQPVMMTGPAVRVYEGQVRL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y5972_BACC7
Sequence: MSTILVLGGSNGRTLEKLAKKRDCQVIFHDGKNHGGVKKTFRSVIKKCDVIVVQKGACGHVSIDVAKEYAKKYDVPLLFNQGFGGTGALEIGLKHLQAA
What are the official names of this protein?
UPF0751 protein BCAH187_C0172.
What is the protein family that this protein belongs to?
Belongs to the UPF0751 family.
Protein: SEN2_RAT
Sequence: MAEAVFRAPKRKRRVYESYESPLPIPFSQDQSPRKEFRIFQAEMISNNVVVRGTEDMEQLYGKGYFGKGILSRSRPNFTISNPKLAARWKGVQTDMPIITSEKYQHRVEWARDFMRRQGHDESTVQKILTDYTEPLEPPYRERKGESPQHEPLSSKADSSLEGREGKDELSVTTGGAGQSDDLQGLNTHSDCRQEGPGHATLTVASPSSLNGHAIEDPEALSQIPCCSQEALGQQDDLWPEASSQIAGESRAAHEYVLIEEELCDVQEGAAPHDELLKRKRLVCRRNPYRIFEYLQLSLEEAFFLAYALGCLSIYYEKEPLTIVKLWQAFTAVQPTFRTTYMAYHYFRSKGWVPKVGLKYGTDLLLYRKGPPFYHASYSVIIELVDDNFEGSLRRPFSWKSLAALSRVSGNVSKELMLCYLIKPSTMTNEDMETPECMRRIQVQEVILSRWVSSRERSDQDEL
What is the function of this protein?
Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA.  It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron.  The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini.  There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.  Probably carries the active site for 5'-splice site cleavage.  The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3'-end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3'-end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events (By similarity).
What are the official names of this protein?
tRNA-splicing endonuclease subunit Sen2, tRNA-intron endonuclease Sen2.
What is the protein family that this protein belongs to?
Belongs to the tRNA-intron endonuclease family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Note=May be transiently localized in the nucleolus.
Protein: RRF_SALA4
Sequence: MISDIRKDAEVRMEKCVEAFKTQISKVRTGRASPSLLDGIVVEYYGTPTPLRQLASVTVEDSRTLKINVFDRSMGPAVEKAIMASDLGLNPSSAGTDIRVPLPPLTEERRKDLTKIVRGEAEQARVAVRNVRRDANDKVKALLKDKAISEDDDRRSQEEVQKMTDAAIKKVDAALADKEAELMQF
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGD_BACSU
Sequence: MSSLFQTYGRWDIDIKKAKGTYVEDQNGKTYLDFIQGIAVSNLGHCHEAVTEAVKKQLDSVWHVSNLFQNSLQEQAAQKLAAHSAGDLVFFCNSGAEANEGAIKLARKATGKTKIITFLQSFHGRTYAGMAATGQDKIKTGFGPMLGGFHYLPYNDPSAFKALGEEGDIAAVMLETVQGEGGVNPASAEFLSAVQSFCKEKQALLIIDEIQTGIGRTGKGFAYEHFGLSPDIITVAKGLGNGFPVGAVIGKKQLGEAFTPGSHGTTFGGNMLAMAAVNATLQIVFQPDFLQEAADKGAFLKEQLEAELKSPFVKQIRGKGLMLGIECDGPVADIIAELQTLGLLVLPAGPNVIRLLPPLTVTKDEIAEAVSKLKQAIAHHSAVNQ
What are the official names of this protein?
Acetylornithine aminotransferase, ACOAT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS3_LISMF
Sequence: MTSVDFSKGLVPTIILDDQNGDVLMLAYMNEESYQKTLETGYTWFFSRSRNELWNKGATSGHTQKVKQIWTDCDNDTLLIRVTQIGPACHTGKKSCFFNLIKEDF
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTH_EDWI9
Sequence: MTIKLIVGLANPGAEYAQTRHNAGAWFVDALAERHGQSLKEESKFFGYTARLSLAGHDLRLLVPTTFMNLSGKAVSALAGFYRIAPDEILVAHDELDLPPGVAKLKLGGGNGGHNGLKDIQSKLGNNPNFHRLRIGIGHPGDKSKVVGFVLGKPLASEQPLIDDAIDEALRCTDLLMQDGMDKAMNRLNGFRASAR
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C1TM_SCHPO
Sequence: MNVMVSFNQLRNYFLESNSLRPSKWLFQSYGTSSSANILNGKLLARKLQRSVAEEVQALKAKDRNFKPALAIVQVGKREDSNVYVRMKEKAARLVGIDFKYCPFPETIQMPALLHELKKLNDDHTVHGVLVQLPLPKHLNERTVTESITPPKDVDGFGAFNIGLLAKNDATPIHYPCTPKGIMELLKDNKISVAGLNAVVLGRSDIVGNPISYLLRKDNATVTVCHSKTKDLIQHISNADLVIAALGKPEFVRGEWLKPGSVVVDVGINAVQRNGKRVLVGDVHFESASKVASSITPVPGGVGPMTVAMLMENIVNAAKIARTENIYRKIDLNPLELKKPVPSDIEIANSQEPKLISNLAKEMGIYDTELENYGNYKAKVNLAVYERLKHRKDGNYVVVSGITPTPFGEGKSTVVAGLVQAMGHLGKLGIACVRQPSQGPTFGVKGGAAGGGYAQFIPMDDFNLHMTGDIHAVTAANNLLVAALETRMFHENTQSDAALIKRLIPVKNGRRVIPRGLIGRWNRICASHNMDPEDVNNASPELLKEFVRLNVDPDTIECNRVLDVNDRFLRSIEVGKASTEKGHVRKTSFDISVASECMSILALSCDLNDMHSRLSRMVIANDKYGNAITAGDLGVSGALTVLLKDAIKPNLMQTLEGTPAFVHAGPFANISIGASSIIADKIALKLAGTESFDRPEDAGYVVTEAGFASDMGMEKFFNIKCRYSKLVPNTVVLVTTVKALKLHGGGPKLKPGAPIPEEYLVENLDLVKNGCSNMVKHIQNCHKFNIPVVVAINSYKTDSSKEHEIIREAALQAGAVDAVPSDHWAQGGKGAIELAKSVMTACDQSSNSKFRLLYDSETSIEDKVNVIAKEMYGANGVEFSSLAKERINTFIKQGFGNLPICMAKTQYSLSHNPEFRNVPKNFTVPIRDMRLNAGAGFIYPLAAEIQTIPGLPTAPAYLNIDICENGEIVGLS
What are the official names of this protein?
C-1-tetrahydrofolate synthase, mitochondrial, C1-THF synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CRCB2_STRPN
Sequence: MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNYLGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLILYLLLSIGGGLLLAYYLGRKKW
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 2.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: QUEC_CHLT3
Sequence: MRAVVLLSGGMDSLVTTAIAAHLGYELAALHINYGQRTEKRELVAFQKICDFYRIERRLEINFEHLSLIGGSSLTDLAMPVTTAKLHSKEIPTSYVAFRNANMLSVAVSWAEVIGANKIFIGAVDEDSSGYPDCRVNFFQAFNELIKHGTKPDTRIEIQTPVISLKKWEIVIKGMELEVPFEHSWSCYKSEHVACGVCDSCALRLRAFEQAGIRDPIEYKIRPSYI
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.