PharMolix/UniProtQA huggingface dataset:
Protein: RPE_ARATH
Sequence: MSTSAASLCCSSTQVNGFGLRPERSLLYQPTSFSFSRRRTHGIVKASSRVDRFSKSDIIVSPSILSANFAKLGEQVKAVELAGCDWIHVDVMDGRFVPNITIGPLVVDALRPVTDLPLDVHLMIVEPEQRVPDFIKAGADIVSVHCEQQSTIHLHRTVNQIKSLGAKAGVVLNPGTPLSAIEYVLDMVDLVLIMSVNPGFGGQSFIESQVKKISDLRKMCAEKGVNPWIEVDGGVTPANAYKVIEAGANALVAGSAVFGAKDYAEAIKGIKASKRPAAVAV
What is the function of this protein?
Essential protein required during embryogenesis (PubMed:15266054).  Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate (By similarity).  Essential for the early steps of nematode feeding sites (NFS, multinucleated root cells) formation induced by the root-knot nematodes Heterodera schachtii, Meloidogyne incognita, M. javanica and M. hapla (PubMed:9843485).
What are the official names of this protein?
Ribulose-5-phosphate-3-epimerase, chloroplastic, R5P3E, Pentose-5-phosphate 3-epimerase, Protein EMBRYO DEFECTIVE 2728.
What is the protein family that this protein belongs to?
Belongs to the ribulose-phosphate 3-epimerase family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane.
Protein: NADD_THEP3
Sequence: MERELRLGIMGGTFDPIHYGHLVTAEAVRSEFKLDKVIFVPAGNPPHKVKRKVTDKKHRYLMTILATITNPFFEVSTIEIDREGYTYTIDTIKEFKKIYGEKTQLYFITGADAVLEILTWKSADELLKMCNFVAATRPGVEGNRIDEELNKIRKLYGNVIYKVTVPSLAISSTDIRERVAGGRPIKYLLPESVERYIQKYDLYKKDEENGV
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: VDH_STRA4
Sequence: MTDVTGAPADVLHTLFHSDQGGHEQVVLCQDRASGLKAVIALHSTALGPALGGTRFYPYANEAEAVADALNLARGMSYKNAMAGLEHGGGKAVIIGDPEQIKSEELLLAYGRFVASLGGRYVTACDVGTYVADMDVVARECRWTTGRSPENGGAGDSSVLTSFGVYQGMRAAAQHLWGDPTLRDRTVGIAGVGKVGHHLVEHLLAEGAHVVVTDVRKDVVRSLTERHPSVVAVADTDALIRVENLDIYAPCALGGALNDETVPVLTAKVVCGAANNQLAHPGVEKDLADRGILYAPDYVVNAGGVIQVADELHGFDFDRCKAKAAKIYDTTLAIFARAKEDGIPPAAAADRIAEQRMAEARARR
What is the function of this protein?
Oxidative deamination of branched-chain amino acids.  Oxidizes L-valine and L-alpha-aminobutyric acid efficiently, and L-alanine and L-isoleucine less efficiently.  D-valine and L-glutamate were not substrates for the enzyme.  The catabolism of valine is the major source of fatty acid precursors for macrolide biosynthesis and a vital source of antibiotic precursors.
What are the official names of this protein?
Valine dehydrogenase, ValDH.
What is the protein family that this protein belongs to?
Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAB2A_RABIT
Sequence: MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHGATNATHAGNQGGQQAGGGCC
What is the function of this protein?
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes.  Rabs cycle between active GTP-bound and inactive GDP-bound states.  In their active state, drive transport of vesicular carriers from donor organelles to acceptor organelles to regulate the membrane traffic that maintains organelle identity and morphology.  Required for protein transport from the endoplasmic reticulum to the Golgi complex.  Regulates the compacted morphology of the Golgi.
What are the official names of this protein?
Ras-related protein Rab-2A.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Endoplasmic reticulum-Golgi intermediate compartment membrane; Lipid-anchor. Melanosome. Endoplasmic reticulum membrane; Lipid-anchor. Golgi apparatus membrane; Lipid-anchor. Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Localized in the Golgi apparatus in the round spermatids and in the acrosome in the elongating spermatid (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV (By similarity).
Protein: IPYR_MACFA
Sequence: MSGFSTEERAAPFSLEYRVFLKNEKGQYISPFHDIPIYADKDVFHMVVEVPRWSNAKMEIATKDPLNPIKQDVKKGKLRYVANLFPYKGYIWNYGAIPQTWEDPGHNDKHTGCCGDNDPIDVCEIGSKVCARGEIIGVKVLGILAMIDEGETDWKVIAINVDDPDAANYNDINDVKRLKPGYLEATVDWFRRYKVPDGKPENEFAFNAEFKDKDFAIDIIKSTHDHWKALVTKKTNGKGISCMNTTVSESPFKCDPDAARAIVDALPPPCESACTVPTDVDKWFHHQKN
What are the official names of this protein?
Inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2110_MYCA1
Sequence: MPRTDNDTWDLSTSVGATATMVAAARAIATNADNPLIEDRFAEPLVRAVGVDFFTRWVTGDLVAADVDDHDSGWKLEHMPVAMAARTRFFDSFFQGATQAGIRQAVILASGLDARAYRLAWPAGTTVFEIDQPQVIEFKTATLAKLGATPQATLRTVAVDLRDDWPKALVEAGFDKGQPTAWIAEGLFGYLPPEAQDRLLDNITALSADGSRLACEAIPDMSEVDTEKAQEMMRRATAKWREHGFDLEFGDLGYQGERNDVAVYLDGLGWRSVGVPMSQLLADAGLEAIPQTNDSVSVADTIYYSSVLAK
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase MAV_2110.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: TYSY_SHEHH
Sequence: MKQYLDLCQRIIDEGTWVENSRTGKRCLTVINADLVYNVDKNEFPLITTRKSFYKAAIAELLGYIRGYDNAADFRKIGCNTWNANANDNQAWLNNPHRKGVDDMGRVYGVQGRAWSKPDGGTIDQLRKIVDDLSKGIDDRGEILSFYNPGEFHMGCLRPCMHTHNFSLLGDTLHLTSFQRSCDVPLGLNFNQVQVFTLLALMAQITGHKAGTAFHKIVNAHIYEDQLELMRDVQIKREPLSSPKLVINPDIKSLEDLETWVTMDDFEVTGYEHHEAIKYPFSV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1601_BORPD
Sequence: MLFLLSPAKKLDYDTPVHVEHHTQPLFVEQSAALIKVLKTLSADDVAALMSLSPALAELNVARYAAWSRKFTQHNARQAVLAFNGDVYEGLQAGSLSPARLDWAQEHVAILSGLYGVLRPLDLMQPYRLEMGTRLATPKGKNLYEFWGSTIADYLNERLAGQKTPIVVNLASEEYFKSVDLKVLKARVVQCVFQDWKNGAWKVISFHAKRARGLMARYAIEHKVAKPEGLQKFDSEGYAFDASASSADKLVFRRKA
What are the official names of this protein?
UPF0246 protein Bpet1601.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: DUT_METPP
Sequence: MTTIDVKVLDPRMADQLPAYATPGSAGLDLRACLDAPLLLEPGQTQLIPTGLSIHIGDPGLAAVILPRSGLGHKHGIVLGNLVGLIDSDYQGPLMVSCWNRGLAAFTVQPLERIAQLVIVPVVQASFRVVDDFGASERGEGGFGSTGQR
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: COXX_METPB
Sequence: MTSLSNSLSADAGRASLASAAGGEVSDFFALLKPRVMVLVIFTALVGMVVSDATVNPVIAAISLLMIAVGAGASGCLNMWWDADIDALMTRTAKRPIPDGRIRPDEALAFGIVLSVGSVLILGLASNWLAAGLLAFTIVFYAVIYSMWLKRATAQNIVIGGAAGALPPVVGQAAVTGHVGIESLVLFAIIFIWTPPHFWALALVKSGEYARAGIPMMPNVAGPDSTRRQIVWYSLLLAPLALVPVWLGFGGWLYAVVGVLGGLGMLAGAVQVYRLREGEPERKAAMGLFAFSILYLFLLFSALLAEQGLGLFRAVAA
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUOA2_PSEAB
Sequence: MYASFAPATWALLAYLFGALALCLLMLGLGRVLGGRSHGRAKNLPFESGVDSTGSSRLRFSVKYALVAMLFVIFGIEMPFLYLWAVSLRENGWAGFVEATLFVSLLLVGLFYLHRVGALDWSPERRRKKPHD
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A 2, NADH dehydrogenase I subunit A 2, NDH-1 subunit A 2, NUO1 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CP7B1_MOUSE
Sequence: MQGATTLDAASPGPLALLGLLFAATLLLSALFLLTRRTRRPREPPLIKGWLPYLGMALKFFKDPLTFLKTLQRQHGDTFTVFLVGKYITFVLNPFQYQYVTKNPKQLSFQKFSSRLSAKAFSVKKLLTDDDLNEDVHRAYLLLQGKPLDALLETMIQEVKELFESQLLKITDWNTERIFAFCGSLVFEITFATLYGKILAGNKKQIISELRDDFFKFDDMFPYLVSDIPIQLLRNEESMQKKIIKCLTSEKVAQMQGQSKIVQERQDLLKRYYRHDDPEIGAHHLGFLWASLANTIPAMFWAMYYILRHPEAMEALRDEIDSFLQSTGQKKGPGISVHFTREQLDSLVCLESTILEVLRLCSYSSIIREVQEDMNLSLESKSFSLRKGDFVALFPPLIHNDPEIFDAPKEFRFDRFIEDGKKKSTFFKGGKKLKTYVMPFGLGTSKCPGRYFAVNEMKLLLIMLLTYFDLEIIDRKPIGLNHSRMFLGIQHPDSAVSFRYKAKSWRS
What is the function of this protein?
A cytochrome P450 monooxygenase involved in the metabolism of endogenous oxysterols and steroid hormones, including neurosteroids (PubMed:9295351, PubMed:9144166, PubMed:10748047, PubMed:11067870).  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).  Catalyzes the hydroxylation of carbon hydrogen bonds of steroids with a preference for 7-alpha position.  Usually metabolizes steroids carrying a hydroxy group at position 3, functioning as a 3-hydroxy steroid 7-alpha hydroxylase (PubMed:9295351, PubMed:9144166, PubMed:10748047, PubMed:11067870).  Hydroxylates oxysterols, including 25-hydroxycholesterol and (25R)-cholest-5-ene-3beta,26-diol toward 7-alpha hydroxy derivatives, which may be transported to the liver and converted to bile acids (PubMed:9295351, PubMed:9144166, PubMed:10748047, PubMed:11067870).  Via its product 7-alpha,25-dihydroxycholesterol, a ligand for the chemotactic G protein-coupled receptor GPR183/EBI2, regulates B cell migration in germinal centers of lymphoid organs, thus guiding efficient maturation of plasma B cells and overall antigen-specific humoral immune response (PubMed:22999953).  7-alpha hydroxylates neurosteroids, including 3beta-hydroxyandrost-5-en-17-one (dehydroepiandrosterone) and pregnenolone, both involved in hippocampus-associated memory and learning (PubMed:9144166).  Metabolizes androstanoids toward 6- or 7-alpha hydroxy derivatives (By similarity).
What are the official names of this protein?
Cytochrome P450 7B1, 24-hydroxycholesterol 7-alpha-hydroxylase, 25/26-hydroxycholesterol 7-alpha-hydroxylase, 3-hydroxysteroid 7-alpha hydroxylase, Hippocampal transcript 1 protein, HCT-1, Oxysterol 7-alpha-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome membrane; Multi-pass membrane protein.
Protein: RL15_PROMP
Sequence: MTSTLNTLKSNTGSRKKKLRKGRGIAAGQGASCGFGMRGQKSRSGRPTRPGFEGGQMPLYRRVPKLKHFEIINQKNFSIVNLSKLSEFKESEVVNIDSLVKKKLLFKPKFPLKILGNGEVKVKLKVQAHAFTKVAKEKIEAAGGSCEIINNK
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: CINA_STRE4
Sequence: MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVIDIASQRSDLVILCGGLGPTDDDLTKQTLAKYLGKALVFDEQAGQKLDAFFAHRKQAARTPNNQRQAQLIEGSIALQNQTGLAVGGLITVDRVTYVVLPGPPSELKPMVKNELVPLLSASHASLYSRVLRFFGIGESQLVTALEDLIKHQTDPTIAPYAKTGEVTLRLSTKADNQALADERLNRLEAQLLSIRTVDNQPLRRLLYGYGEDNSLARETFELLKRSGKTITAAESLTAGLFQAQLTDFAGASQVFNGGFITYSIEEKARMLGIPLGELQRHGVVSSFTAEQMAAQARCLTNSDIGIGLTGVAGPEALEGQPAGTVFIGLATKNKVESLKVVIGGRSRLDVRYIAALYAFNMVRKTLLKSENLL
What are the official names of this protein?
Putative competence-damage inducible protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: RBSD_PSEPG
Sequence: MKKTPLLNVALSRVIAGMGHGDILVIGDAGLPVPPGVEMIDLAVTPGLPDFASVLRAVLSELQVERHVLAEEMQKVVPPALVEIERLKGKLGKREWLSHENFKVLSRSARAVVRTGECQPYSNIALISGVTF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_AKOMY
Sequence: MKILRKNHPLLKIVNHSFIDLPTPSNISSWWNFGSLLGMCLVIQILTGLFLAMHYTSDTTTAFSSVAHICRDVNYGWLIRYLHANGASMFFICLFIHVGRGIYYGSYVLSETWNIGIILLLTTMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGNTLVEWIWGGFSVDKATLTRFFAFHFILPFIIAAFALVHLLFLHETGSNNPSGLNSDSDKIPFHPYYTTKDLLGIFLLLLVLMILALFFPDVLGDPDNFTPANPLNTPAHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILATFPLLNTSKQHGLIFRPVTQVIYWIFIANLLVLTWIGGQPVEYPFTTIGQIASITYFTIIIILIPVSNTIENNIIKL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: METK_METAC
Sequence: MARNIKVEELLQTPIEKQRIELVERKGIGHPDSISDGLAEAVSRALCREYISKCGTVLHHNTDETQIVAGRSSPKFGGGEVLQPIYMLLVGRATKEFEGVELATESVALQAARNYLRKTMVNMDLERDVIMDCKLGTGSSDLRDVFKRDRVPVANDTSFGVGHAPFSELENIVYNTERRLLTDLKSRMPAIGEDMKVMGLRDGEDIALTICSGMIGKYIDDLDSYINMTQEMKIYVEELATHYTERDVNVYINTGDNLKTSCVFLTVTGTSAEMGDDGSVGRGNRCNGLITPNRPMSMEATSGKNPINHIGKIYNLLSTQMARDIVKQVPEVQDVYIRLLSQIAKPIDQPLVASAQIIPKEGTSFEKVKSEAEVVIDDWLSNVTKITEMVIRGELNTF
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase 2 family.
Protein: FLIE_EDWI9
Sequence: MAVTGIENVLQQLQATALSAANGTPQDGVAQGTFSSELKAAIDRISDNQNHARLQAQQFEMGVPGVALNDVMLDMQKSSVSLQMGVQVRNRLVAAYQDIMNMQV
What are the official names of this protein?
Flagellar hook-basal body complex protein FliE.
What is the protein family that this protein belongs to?
Belongs to the FliE family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: CYB5_HUMAN
Sequence: MAEQSDEAVKYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDATENFEDVGHSTDAREMSKTFIIGELHPDDRPKLNKPPETLITTIDSSSSWWTNWVIPAISAVAVALMYRLYMAED
What is the function of this protein?
Cytochrome b5 is a membrane-bound hemoprotein functioning as an electron carrier for several membrane-bound oxygenases.
What are the official names of this protein?
Cytochrome b5, Microsomal cytochrome b5 type A, MCB5.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b5 family.
What are the subcellular locations of this protein?
[Isoform 1]: Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side. Microsome membrane; Single-pass membrane protein; Cytoplasmic side. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm.
Protein: HEMH_BRUMB
Sequence: MSGTDKVRVNVSQTAQTPLHTSAKLPKVGVLLVNLGTPDGTSYGPMRRYLAEFLSDRRVIEWSRLIWYPILYGIVLNTRPRRSGRLYDRIWNHENNESPLRTYTRAQGEKLAKALSDQPNVVVDWAMRYGQPSIESITDRLLQQGCERIVIFPLYPQYSATTTATVNDKFFEALMKKRFMPAIRTVPSYEAEPVYIDALARSVEKHLATLSFKPEVILTSYHGIPKSYSDKGDPYRQQCLETTRLLRERLGLGEDEMRATFQSRFGPEEWLQPYTDETVKELAKNGVKSVAVLNPGFVADCLETVDEIGNEAAEEFLENGGENFSHIPCLNDSEEGMKVIETLVRRELLGWV
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LNT_THEMA
Sequence: MNRRRWWRSSERRWRGLVSLFLSVLSGFLTALSMPGFLSGALIWFSLIPLLYAVEGRGVWKRAFLSFVYFFTHVLISFFWVLPTLTENVPLVFGRYPSWLGIVVFVLMGIIEAVPFLGFGFLSYFAPQSIVLKTLYLASVYTIFEYLRGVGELGFTGGRISEALYSHTGLIQIVSITGTLGLVFLIVSLNVLFYEFLRRRKGLLIFPVIFFVYLLNSSVVHLLPVPERGSFKVVALQPNVPTSLKYSVSSGEMLELLESMTKDFHGSIVITPEAFFLEDVRYSQKLRELSEENTFVIGFPADNQNSVFVLEGGRFRKVYSKVKLFPFVEKLPYPRVFGVFSFLKGLSYYEPGRNFSVFNVGESPPLSVQICFESYFPEVSRAFVKNGSELLIVVTNDGWFHYKAALLNHFVQGVFRAVETRRQFLQVANTGITGLVDEYGRIVDALPLRVRLAGEFHIKARKGETFYVRYGDWFFYLSVILAVVSVFISRMRGERNEGIGIRL
What is the function of this protein?
Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
What are the official names of this protein?
Apolipoprotein N-acyltransferase, ALP N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LOLA5_DROME
Sequence: MDDDQQFCLRWNNHQSTLISVFDTLLENETLVDCTLAAEGKFLKAHKVVLSACSPYFATLLQEQYDKHPIFILKDVKYQELRAMMDYMYRGEVNISQDQLAALLKAAESLQIKGLSDNRTGGGVAPKPESSGHHRGGKLSGAYTLEQTKRARLATGGAMDTSGDVSGSREGSSSPSRRRRKVRRRSMENDAHDNSNSSVLQAAASNQSILQQTGAGLAVSALVTTQLSSGPAAGTSSQASSTQQQQPLTSTNVTKKTESAKLTSSTAAPASGASASAAVQQAHLHQQQAQTTSDAINTENVQAQSQGGAQGVQGDDEDIDEGSAVGGPNSATGPNPASASASAVHAGVVVKQLASVVDKSSSNHKHKIKDNSVSSVGSEMVIEPKAEYDDDAHDENVEDLTLDEEDMTMEELDQTAGTSQGGEGSSQTYATWQHDRSQDELGLMAQDAQQRDPQDEAGQNEGGESRIRVRNWLMLADKSIIGKSSDEPSDKLTQSKKSLISDAKTTNKTSTPIRPKVSTTTTSTSTAAAAAAAATIAAKQAAAAIASSNINNNNSSLTQTVTQTVTRIGSIGRTTIACITPANNGNKSSSSNCNVDAASAAALAAAGVELDSIDDTMTEVIVKIENPESMPLNDDEDDAVCNEAIEDENTFDYDLKLGSPLSWTYDAVKIENEEFEDSYLMDNDDDDDDLLTTAAATQKHAKQSNEKQMAGSMVAGAGSGGAVKKIVLSAQQQQQLLEQQQHLQHLQLQPTSQSLQIKLPAIPATITTISAPKQMMSGAGTSGSLTPNNNCTLMSNKLGLPVKGQNLDLHWSHSDDNRYRVLVQNKRTRKESLEHSADMIYNADIEKPWVCRNCNRTYKWKNSLKCHLKNECGLPPRYFCSKMCGYATNVHSNLKRHLNTKCRDREKDADDEKKPGSASGNMPVVVGVGNGTAVPVSSSNNNNNGGGSSTSSTYTLVFQNDSA
What is the function of this protein?
Putative transcription factor required for axon growth and guidance in the central and peripheral nervous systems.  Repels CNS axons away from the midline by promoting the expression of the midline repellent sli and its receptor robo.
What are the official names of this protein?
Longitudinals lacking protein, isoforms J/P/Q/S/Z.
Protein: HBE_BRAAR
Sequence: MVHFTAEEKAAITSLWGKMNVEEAGGEALGRLLVVYPWTQRFFDNFGNLSSPSAILGNPKVKAHGKKVLTSFGDAIKNMDNLKTTFAKLSELHCDKLHVDPENFRLLGNVMVIILATHFGKEFTPEVQAAWQKLVSAVAIALGHKYH
What is the function of this protein?
The epsilon chain is a beta-type chain of early mammalian embryonic hemoglobin.
What are the official names of this protein?
Hemoglobin subunit epsilon, Epsilon-globin, Hemoglobin epsilon chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: CARML_DICDI
Sequence: MSEEISPNDRKFITNLLTQKNQESLLLSIGDKISKKKNKKPSKRIILITKNRIFFLKPSQNKVKKDIHLLDIQEIKSSTSNEFTIVAKVDNKQFSYGLITNKTDEIINQIRVTFNHQFFGCPEESTFKCTDIKDSRLVEIEQKDLPCGGFVETYQSICDHLGVPPRDDICWDMTNIISSKNIRSFNIGEIELPTSAGDTIRCLLGALKYNNYFKSFNFNNYTFNKEQFGYLAEVLKCNSTVEDLSLNNVGLKHDTMPIIATALSSNKNLALTAIDISNNQIEDKGMTAFSSYVASSLRGIASLDVSNTNCNKAGISVLTNALKKNIKMSSTLSYLNLSGNKMEADGSAGLSSFLASPNTLKTLNISNTTPSMETIVGALVIGCAELKTIDISDNKLTKKEVPHLVRFIGASSTLKHFNLSGTKVPVENLKELVVAITSNIYLQDVVLDLKNNDLGIAGARMLASLATDKLSNVIYLDVSENDFGDEGVSVICDGFVGNSTIKKLILNGNFKQSKTKSRPSAIESVISLLESECPLETLHMTVGNSKSPLKADILSLIYSLATNSSLLELDISGHQMGPKGAIGLGKALQTNKTLHTLIWDDNLTTAIGFAGFQVGLERNLTLKNMPTPLNDIIQCHREPKFQQIWKEIDSCINRNQSPTRAFEGNGGNSIGATNLSFLASGQQQGVEKLLNKIKSIGRKVTDPNNILIVKDAESTEKVIGGIHLIKESIHASLEMELNQKLKDFVQVVNDVINAKKNEMTQQILESMQNTFQSMDGPTIKRLATTIQYGSKDVDEQQIHSTLVKGAGAELSSRAHECFISALDIASDYTYEKITIGLDSVFKDLILEESQAQNEASGATPIPDSPVPTRSPQPTSPPITPQPTPTTNVPPVTAPRTGAAAPLKPANPPPVSTTTTPPVSTTPKPTQPVSKFGAKLSANSAVAEAIARNMGGGAPPIRKPVAPEPEPEPVTPTKDVTPLKSKPVVAPRSTPTTSTPTKTPVKKPSGPSVPGSLSDAPESDSAELTHVTASRPHIASKRKPPTRRPRPPTEN
What is the function of this protein?
Serves as the scaffold for the assembly of a complex that links key players in the nucleation and termination of actin filament assembly with a ubiquitous barbed end-directed motor.  This complex is composed of at least capping proteins (acpA and acpB), the Arp2/3 complex, type I myosins (myoB and myoC) and carmil.  It has at least a modest ability to activate Arp2/3-dependent actin nucleation.  CARMIL localizes along with the Arp2/3 complex, myoB, and myoC in the leading edge of cells and it plays a significant role in the structure and function of these actin-rich cellular extensions.
What are the official names of this protein?
Protein CARMIL, dDcarmil, Capping protein, arp2/3 and myosin I linker, Leucine-rich repeat-containing protein p116, p116.
What is the protein family that this protein belongs to?
Belongs to the CARMIL family.
What are the subcellular locations of this protein?
Cell projection, pseudopodium. Note=Found in dynamic actin-rich cellular extensions, including the leading edge of cells undergoing chemotactic migration, and dorsal, cup-like, macropinocytic extensions.
Protein: GRF10_ORYSJ
Sequence: MDEEKEADSPQPPSKLPRLSGADPNAGVVTMAAPPPPVGLGLGLGLGGDSRGERDVEASAAAAHKATALTFMQQQELEHQVLIYRYFAAGAPVPVHLVLPIWKSVASSSFGPHRFPSLAVMGLGNLCFDYRSSMEPDPGRCRRTDGKKWRCSRDVVPGHKYCERHVHRGRGRSRKPVEASAAATPANNGGGGGIVFSPTSVLLAHGTARAT
What is the function of this protein?
Transcription activator that plays a regulatory role in gibberellin-induced stem elongation.
What are the official names of this protein?
Growth-regulating factor 10, OsGRF10, Transcription activator GRF10.
What is the protein family that this protein belongs to?
Belongs to the GRF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPE_LACH4
Sequence: MADPEKLFRVDVVTPNGMIYSHRGSIVDVRAIDGERSIMYNHVPLLTPLVISEVKVKRSREMDSRIDHIAISGGYIEFSNNVATIIADSAERARNIDISRAQAAKERAEKRLKEAREKHDERTLERAEVALRRAMNRISVYNTKGH
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.