PharMolix/UniProtQA huggingface dataset:
Protein: CH10_SALPA
Sequence: MSIRPLHDRVIVKRKEVESKSAGGIVLTGSAAGKSTRGEIIAVGKGRILDNGTVQPLDVKVGDIVIFNDGYGVKSEKIDNEEVLIMSESDILAIVEA
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1654_ARCFU
Sequence: MNNFKLIVRKWYIPVLIISLITLVASAYALYWATIPETKETQISIRHYSALAYFSGGAEVKKDNPIWANGSFVTLPVYSYSLTPEYSGEFYFTTAPRGDITIETEAKIVYFYEVSDAPVWEKVYYAASNTSRGEIKTNFKINVTDLKSKINEAQNSFGVYLGKTGARIDVSVHYYGKITGKDVDETLSFKIPIDVQSTYYSFSTLNETRDFEMPSTRVVEVQKPLHMKVIPAALCTVSIIFAGLSVVYRTKYSDVSSLEREIERVSWEKKLKEVSFARMPETNLEMVEVERFEDISKAAEETFEHLFYDREKGVFFFIHGGVLYYCREK
What are the official names of this protein?
Uncharacterized protein AF_1654.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: POL1_GCMV
Sequence: MMDSTIILPYAKYNYSLNKYLFYNSNLDIDLDSFNFYKKYNNTLSLLKRKFLDLFCIPVSSSSPPAIQKNGLLSASNPKHLFAFANFVLDCGVNPFLQIWEETLANWPLFQGQSLLACCRTTAEVRREAAEASAEILRLKQVEREHAFQAEVKSLIAAGALPACAEGLARKIWSAGKDQRKVRVAIRTKLTKANALGAAHRSAVATAQAKAEVLREFEPSPAHIQIAVKAHIFAEKLSRKYADLTAQVRARRAAARDLRAKEIYLEIVDLLGAPLLSIPQQIKIKGKYLRRSVAAEVEVPHTRNPMAELVPYKGLGAVSADPRCWVVAQCGKFSATHANLCSEIYSMVIGPWVQLTDFSSIRQFVMNISFLKDFYPEDALIASLKEVNTEAQLAVAAIVTQEEVSKMEANARSANCRANIFKRIASRITSAACSVKNAFLDGCELTGKRLSEGVFSVVIGHFREALTTIKFELGVAMELVEVLIARVKSWFDTLLAKIDHALASLGKWACYALGILLGIGLCNLIETIIGGHGMLVSLFCTGVFATMAIKCAGGWDAAQREMVAMITTLAQSIFGRRKGLDSTDLNTRSIPLLTNVITAMTTFGTGLCKFQSSSIIEIGKLAGACHQMRMGKEALKEFAAMIMHYLGRIADKITGRETIFFDELSTLVSVDVRGWIRCAQGAILESYHTDPGCETFQDVIGRLVQEGQKLQVGVNGIPRKISADYASLIGQIMKDLLELQKRMMRCGTVTGRRKEPVWIYLWGPSHCGKSNFMDVLGMALCKHFDLPYTVCGRNVKDSFFSGYMGQTIMEIDDLSSIKTDPPMEGELINLVSCKDYPLNMADVADKPIYFKSQFVISSSNQEDVPAGAGVRDISSYRSRKAALIEVRRKPGVIFDPDNAMAASQARFKDPMTHMLLNGQNDENSWMEMDDVITECINISARHRAAQEKLQNASLRAKASLDPVTLASQEFLRKEVNSVYLEIPTLEIEKAGISGVRGGRCLYADGILYTLGTEFQLIPHPVENEGYQKLWAQRMKNMYLPAVTTGRYLNASSMIVTGFLRSLVNGDCAVLSVDALSTTATFTQKRIFESLNLAERVYLRALQCQIDAYTLDIPENPYSNVCWVKMLKALGQGREFIVSNGGGILMIAAAIILVLVCGWGFWKAFVGLFTGSMSLGAALAGCQEAEVKAHSVYSADGGDRGYRSRNIPINHRYSYARSQAGNGLLPASRLCVAIYGPRGVFISGMQYKNKCVMMTRHQAQSLNEGDELSVVFASTGESMMIRFHAYHIRENVGSEVVCWLAPSLPQLPCDLKGLFLEDAEVELPSNFKSMGYVLRQDSNAFHYDTLDTYAAVDKTPLVLKGVNGDDLYIHEIPEKIVFHYESRNNDCGMLLTCQLSGKMKVVGMLVAGKDKTSWACILPNPHLAELKSQIEYIPEFGEAEEGYFKVGHVSPKEAPTMPKKTNSVQVPQALRVPCDLPIKEPSIISKNDPRCPANVDPPKAAMKKKFQQPMLDLDQKCLDEIAGDMLETWYDCEDSILSDIPLATAINGIPAGCEDAELENFVMKTSPGYPYFKNKGLGKGKHPYFEECEDGSLKLKEGSQAAELYENMAQFAKEEVPELVVIECPKDELLPARKIKVGPCRLFEIMPLHYNLLLRVKTCAFTAFLQHNRHRLPCQVGTNPYSREWGHLLNRLRRVKTNEAINCDYSGFDGLLTPQLVEMMAKMINRLYLRSGESEVMQAQRLNMIMALCGRYALVGTQVYKVNCGLPSGFALTVVMNSIFNEILIRYAYKTLAPTPEKNSFGINVCLLVYGDDNLISVSPAVASWFTGEAIRVTLAEKRIKITDGSDKDAPTIEAKPFSELDFLKRKFYVHPEHGQVWAPLDKSAIFSCLHWLTPQKSKFALQEKACDYLGEVDVVEELIINVNVSLVELYLHNDKEEFNRVRSFYIARLPMQVDQFRTWAFCEAFHSAQQTGMLRHDPAKILDSLAGPEFPRFMRCSGEGDKAHFYTPILGVCGPHYKPKEQDFLVSTLPIKQGEGVHIPIKIGGGVGGLPTHQWVKNFGRPSQLKNNDGYACYKLLCEQIEQGKRLVFMSAAPYVAGNAALISFGSSRKILKEQMPLCHYRNSIPESVDGLTGYFDAPLPAATIGKSYFANGETYAALCEFKNGEVLDIVGPTNVQILNGAVRQGKVPCLAAHSVGTKFKVSLVCNKTMCPHHHHTGPTFEQAFRTCWLSKCKTKETQVSPWFGTKFLGIS
What is the function of this protein?
Picornain 3C-like protease is a thiol protease that cleaves the P1 and P2 polyproteins.
What are the official names of this protein?
RNA1 polyprotein, P1.
What is the protein family that this protein belongs to?
Belongs to the nepoviruses RNA1 polyprotein family.
What are the subcellular locations of this protein?
[Viral genome-linked protein]: Host endoplasmic reticulum lumen. SUBCELLULAR LOCATION: [Putative ATP-dependent helicase]: Host endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: TBA3_BOVIN
Sequence: MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKLDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGVDSVEAEAEEGEEY
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers (PubMed:6504138, PubMed:2207090, PubMed:7704569).  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin (PubMed:6504138, PubMed:2207090, PubMed:7704569).
What are the official names of this protein?
Tubulin alpha-3 chain, Alpha-tubulin 3.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RR11_BUXMI
Sequence: MAKPIPRIGSRKNGRIGSRKSGRRIPKGVIHVQASFNNTIVTVTDVRGRVVSWSSAGTCGFRGTRRGTPFAAQTAAGNAIRTVMDQGMQRAEVMIKGPGLGRDAALRAIRRSGLLLSFVRDVTPMPHNGCRPPKKRRV
What are the official names of this protein?
30S ribosomal protein S11, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ISPD_ECO45
Sequence: MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHALLAHPRVKRVVIAISPGDSRFAQLPLANHPRITVVDGGEERADSVLAGLKAAGDAQWVLVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYLTRTIHQENT
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: YKVN_BACSU
Sequence: MKKFSCGFEVTKEVIGGKWKGLVLYFLMNGPKRTSELKRIIPNITQKMLIQTLRELEASGLVSRKMYNQVPPKVEYSSTELGESLKPILQELCQWGGYYAEQEYAEGEYEIVQPEQLS
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator YkvN.
Protein: BZP53_ARATH
Sequence: MGSLQMQTSPESDNDPRYATVTDERKRKRMISNRESARRSRMRKQKQLGDLINEVTLLKNDNAKITEQVDEASKKYIEMESKNNVLRAQASELTDRLRSLNSVLEMVEEISGQALDIPEIPESMQNPWQMPCPMQPIRASADMFDC
What is the function of this protein?
Transcription activator that binds DNA to the C-box-like motif (5'-TGCTGACGTCA-3'), ABRE elements, G-box-like motif (5'-CCACGTGGCC-3'), DOF (5'-AAAG-3'), I-box (5'-GATAA-3'), BS1 (5'-AGCGGG-3'), MY3 (5'-CGACG-3'), 5'-CAGTGCGC-3' and 5'-ACTCAT-3' sequence in target gene promoters (PubMed:15047879, PubMed:16810321, PubMed:19531597, PubMed:21278122, PubMed:25108460).  DNA-binding and subsequent transcription activation is triggered by heterodimerization with other bZIP proteins (e. g.  BZIP1, BZIP10 and BZIP25) (PubMed:16810321, PubMed:19531597, PubMed:21278122).  Promotes POX1/PRODH1 expression in response to hypoosmolarity stress (PubMed:15047879, PubMed:16810321).  Transcriptional activator of seed maturation (MAT) genes (e. g.  AT2S2), including seed storage protein (SSP) and late embryogenesis abundant (LEA) genes (PubMed:19531597).  Activated by low energy stress both by transcriptional and post-transcriptional mechanisms.  Promotes dark-induced senescence and participates in the transcriptional reprogramming of amino acid metabolism during the dark-induced starvation response, especially when heterodimerized with BZIP1, by triggering accumulation of specific proteins including ASN1 and POX1/PRODH1 (PubMed:21278122).
What are the official names of this protein?
bZIP transcription factor 53, AtbZIP53.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MTD_METST
Sequence: MVVKIGIVKVGNIGTSVLIDMILDERADREDIDVRTISSGAKMGKNQMDDVLPKIDEYNPDVIIFISPDPGAKSPSSARETLSKKNIPTIVIGDGPGERAIGSMKEQGLGYIIVKADSMIGARREFLDATEMAVFNSDVLMVLSTTGVFRLIHKTLDKVIRDIDEDKLYSLPELVITAENAVDAADFKNPYAKSKAIAAYSIACQVSSMNVRACFKTKDYHVYIPLVSAAHEMMSAASKLAYEAREIEKSNDTVVRTAHRRNGSILYGTSLNDNKE
What is the function of this protein?
Catalyzes the oxidation of methylene-H(4)MPT to methenyl-H(4)MPT(+).
What are the official names of this protein?
F420-dependent methylenetetrahydromethanopterin dehydrogenase, MTD, Coenzyme F420-dependent N5,N10-methylenetetrahydromethanopterin dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MTD family.
Protein: WIP3_ARATH
Sequence: MNESVPDSVEDNGNSVPANGLLVLPDNDHEEGGVGSPQRSNSVESPGGSVHSTRKGFGLKKWRRIKRDGPVRDEAAPVDDGSKLLKRGLAGLVNPPSKHVEFSSVEARQSSEGSVGSVNMVHHPGVANGFSPDIGCMFAVGQAFEKSEEHSGNTIGGKNVVGGKVVSGSQEKLWSDTIKRASEERGDIEKEKPCSSLDSDLRSSDFVFSTGSVSVGNHGEKDERLTMNYIGGFSNEGQVKEEVQTYSRSENGNKEDDGESKKNNNHWADKDALADSIRSFAVLQEVLWKEVQSFQELGKESVLLHSNTDELSSDQPSHQNCKEDNSTSSGSKALILKEKVKLLEHKLEEARAALEAKEARIQELENSKIESELECIFQRKIETEIEHLMLTRSLSSLQVLQETKKLHSLKEDPVSNRGNILGKTCKLGFYILTQLILLVSILRFLVLQFSPASRLVIPT
What is the function of this protein?
Mediates and enhances the nuclear envelope docking of RANGAP proteins mediated by WIT1 and WIT2 in the undifferentiated cells of root tips (PubMed:17600715).  As component of the SUN-WIP-WIT2-KAKU1 complex, mediates the transfer of cytoplasmic forces to the nuclear envelope (NE), leading to nuclear shape changes (PubMed:25759303).
What are the official names of this protein?
WPP domain-interacting protein 3.
Protein: TXS6C_CUPSA
Sequence: FLNPFRWVINKYR
What are the official names of this protein?
Short cationic peptide-6c, SCP-6c, Short cationic peptide-6i, SCP-6i, Truncated variant of Cupiennin 6 family.
What is the protein family that this protein belongs to?
Belongs to the cationic peptide 04 (cupiennin) family. 06 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GU01_RAT
Sequence: MYLFLSNLSLADISFTSTTLPKMIVDIQTNNRAISYSGCLTQMSFFMLFGCLDSLLLTAMAYDRFVAICHPLHYQVIMNPRLCGLLVFLSILISLLVSQLHNSVVLQLTYFKSVDISHFFCDPSLLLNLACSDTFTNNIVMYFVGAISGFLPISGIFFSYYKIVSSILRMPSPGGKYKAFSTCGS
What is the function of this protein?
Possible taste receptor.
What are the official names of this protein?
Putative gustatory receptor clone PTE01.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NU3M_MOUSE
Sequence: MNLYTVIFINILLSLTLILVAFWLPQMNLYSEKANPYECGFDPTSSARLPFSMKFFLVAITFLLFDLEIALLLPLPWAIQTIKTSTMMIMAFILVTILSLGLAYEWTQKGLEWTE
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 3, NADH dehydrogenase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NUOB_BACC2
Sequence: MVINFEELHPNERVELERNIFFSTLEQLKGWARSNSLWPMTFGLACCAIEMMGVGSSHYDLDRFGSFFRTSPRQSDVMIVSGTVTKKMAPIVRRLYDQMPEPKWVIAMGSCATAGGPYVNSYAVVKGVDQIVPVDVYIPGCPPNPAALIYGINKLKEKIRYEAKTGKQVTNK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y2703_LISMO
Sequence: MRGMGNMQGMMKQMQKMQKEMAKAQADLEAQEFTGTAGGGMVTVKATGKRVITDVVINEEVVDPEDIEMLQDLVLAATNDVLKQIEDTTSQTMGKFTQGLNIPGM
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein lmo2703.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: PB2_I02A7
Sequence: MERIKELRDLMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNPALRMKWMMAMKYPITADKRIMEMIPERNEQGQMLWSKANDAGSDRVMVSPLAVTWWNRNGPTTSTVHYPKVYKTYFEKVERLKHGTFGPVHFRNQVKIRRRVDINPGHADLSAKEAQDVIMEVVFPNEVGARILTSESQLTITKEKKEELQDCKIAPLMVAYMLERELVRKTRFLPVAGGTSSVYIEVLHLTQGTCWEQMYTPGGEVRNDDVDQSLIIAARNIVRRATVSADPLASLLEMCHSTQIGGIRMVDILRQNPTEEQAVDICKAAMGLRISSSFSFGGFTFKRTSGSSVKKEEEVLTGNLQTLKIRVHEGYEEFTMVGRRATAILRKATRRLIQLIVSGRDEQSIAEAIIVAMVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKLLFQNWGIEPIDNVMGMIGILPDMTPSTEMSLRGVRVSKMGVDEYSSTERVVVSIDRFLRVRDQRGNVLLSPEEVSETQGTEKLTITYSSSMMWEINGPESVLVNTYQWIIRNWETVKIQWSQDPTMLYNKMEFEPFQSLVPKAARGQYSGFVRTLFQQMRDVLGTFDTVQIIKLLPFAAAPPEQSRMQFSSLTVNVRGSGMRILVRGNSPVFNYNKATKRLTVLGKDAGALTEDPDEGTAGVESAVLRGFLILGKEDKRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDSSILTDSQTATKRIRMAIN
What is the function of this protein?
Plays an essential role in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNAs are used to generate primers for viral transcription.  Recognizes and binds the 7-methylguanosine-containing cap of the target pre-RNA which is subsequently cleaved after 10-13 nucleotides by the viral protein PA.  Plays a role in the initiation of the viral genome replication and modulates the activity of the ribonucleoprotein (RNP) complex.
What are the official names of this protein?
Polymerase basic protein 2, RNA-directed RNA polymerase subunit P3.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB2 family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: HBA_MACFA
Sequence: VLSPADKTNVKAAWGKVGGHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTLAVGHVDDMPQALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-A/Q/R/T, Alpha-A/Q/R/T-globin, Hemoglobin alpha-A/Q/R/T chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RL5_SYNC1
Sequence: MGARLKEVYSTEIAPALVKRLQLKNVMEVPRVEKVVLNMGLGEAIQNIKVLESAVEELTRICGQKPVVTKAKKSIAQFKLREGMPIGCMVTLRRDKAYEFLDRLINVALPRVRDFKGVSKKGFDGRGNYTLGIREQLIFPEIDLEKVDKVKGLNVTIVTTAKNDEEGYALMEAIGMPFPKKAQD
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: NUCS_CORA7
Sequence: MRVVIAQCSVDYVGRLDAHLPMADRLILIKADGSVSIHADDRAYKPLNWMTPPCTFEESAIEDIDGEDTGEKLWLVENPKGEQLRITIAQIHQEIDMDLGEDPGLVKDGVEAHLQELLAEHIETLGEKYSLVRREYPTAIGPVDIMAKNSKNEFVAVEVKRRGGIDGVEQLTRYLELLNRDDLLAPVHGVFAAQEIKPQARTLAEDRGIRCVVLDYQELRGIESNELRLF
What is the function of this protein?
Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
What are the official names of this protein?
Endonuclease NucS.
What is the protein family that this protein belongs to?
Belongs to the NucS endonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_SHEPW
Sequence: MKTAHEVRPGNVIMLDGNPWVVLKTETSRSGRNAAVVKLKLKNVLLDSTTETSFKGEDKLDVIVLDRLDCTYSYFADPMYVFMDEEFNQYDVEAENLGDAAAYITDGMEDVCQVTFYEEKAISVELPIIVTREVTYTEPSARGDTSGKVMKPATIAGGSTLSVADFVKTGDMIEIDTRTNEFKKRV
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXT_SULIA
Sequence: MKIGIIAYQGSFEEHYLQLKRAFDKLSINGEITPVKIPKDLKDIDGVIIPGGESTTIGLVAKRLGILDELKEKITSGLPVMGTCAGAIMLAKEVSDAKVGKTSQPLIGAMNISIIRNYYGRQRESFEAIIDLSKIGKGKANVVFIRAPAITKLWGKAQSLAELNGVTVLAEENNILATTFHPELSDTTSIHEYFLHLVKG
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: DAAF9_MOUSE
Sequence: MDSFDPQQLGLSPARFAGTFGSGAASVSCSRLRQVQSVLTQSSKSQPDGILCILGIDSRYNEGCRELANYLLFGLYSQNATDFEKTGFSEEILDDVILLIKSDSVHLYCNPVNYRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKISSFVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYELQDVSLSLWNVYSRMDPASLENMLSEDLAVFEHQWTSFFANFDTEIPFLLELSESQAGEPFRSYFGHGMLSSHITENSPHRQPFVLFGNHSTRDNLSAGSFNFPSEGHLVRNTGPAGSFAKHMVAQCVSPKGPLACSRTYFFGATHVPYLGDNEKLPRTTEQIRLLSQIYAAVIEAVLAGIACYAKTCSLAKAKEVAEHTLESGLVFTELVPFKADLRSKVTFHIHAVNNQGRIVPLNNEDSLSFVKTARMTVYDIPDLLGGGGGGCLGSVVFSESFLTSRILVKEKDGTITPETSYIILTAAIPRFCSWLVEDSEIKLSEKTLQATKGDDCCLGTLLTGGKGAYLYSNSPQSGPEEGSAYFFSGGLLFSHRHHGSIVIAKEHVDAFSFYDGDSTSVVAALLIHFRSSILPHLPVHFHGSSNFLMLALFPKSKIYQAFYSEVFSPWQQQDNSGLSLKVIQEDGLSAEQKRLHSNAQKLFSALSPPAQDWSSPKLLSGKLPELDRFLQHFAIGSIGQEPVMRAHLVGLLQQPEMSPAHEVESDKVVISIVTGLPGCHASKLCAFLITLHKEYGRWMVYRQIMDSSECFHAAHFQKYLSSALEAQQNRSARQSAYIRKKTRLLVVLQGYTDVIDVVQALQTHPDPNVRSYFTIGAVTVCVEPLSCYMEHRFLFPKCLDQCSQGVVSNVVFTSHTAEQKHPLLVQLQTLIRASNPTAAFILAENGIVTRNEDIELILSENSFSSPQMLRSRYLLFPGWYEGKFDAGSVFPLMVQICVWFDCPLEKTRFVSRCRAIQSSIKPSPFSGNIYHILGKVKFSDSEKTMEVCHNTLTNSLTIVPVLEGPTPPPNSRSSPQDNGQPECYLVFIGCSLKEDSLKDWLRQSAKQRPQRKALKTRGMLTQQEIKNIHVKRHLDPLPAGYFYNGTQFVNFFGDKTDFHPLMDQFMNDYVEEANREIERYNRELEQQEYRDLFEQKPKP
What is the function of this protein?
May act as an effector for ARL3.
What are the official names of this protein?
Dynein axonemal assembly factor 9, DNAAF9.
Protein: YAA7_SCHPO
Sequence: MPCILYMDDTSCLIDLPTSLQFNKHILPTRTKPVVKPYLLPEKSTSDYENSGKGTVGQVLQSLQRVRRALQLRSLDDNQSTDKSHHVQFQDIVYRSNTSASEIHFQAENAPLVQWYSDIFKVLVKAPVIQFEDQCLQWLKMLNTIPPSYSFITIKSKDTVELGLEEIYQQCVQNDGASAIKLKLKGSKVITESSETNCRDSIYYIPARSSFIMGDVEKTAQILLEAIDGHLEKPKCIIIDPPWPNKSVARSSVYKVNRNLGYLKALPIQESLSKTGVVAVWCTNKEKYVNFVKKVLFKKWNLTLVSTWTWLKITAFGEPLFDVYSNMRKPWEQLLIGVTSEYTSVYSDKIPPTFTIIGIPDYHSRKPSLKPFISRWFNCSANESLPVLEIFGRSLTPNWITWGREPLLFMHELYWSSDN
What are the official names of this protein?
Uncharacterized protein C22G7.07c.
What is the protein family that this protein belongs to?
Belongs to the MT-A70-like family.
Protein: RUNX1_CAEEL
Sequence: MTNVFHHVRNFIEQQPAPAKTLEKSSSPNILYTALPKHWRSNKSFQEPFYVVLLTPVPDNTEVSIWAGNDEKPCEEVRNEKAKVHRQVAKFNDLRFVGRSGRGRKFHLTIVIHSAPMMVATVKNVIKVTVDGPRDARIPKPQGSLKRQAEQQTIFPNDIIRTPGPPMPMTMIPPPWFPLPMTQTFPPSFFPLISPGPHPSISAALWKIHSESMKTPIKQKVEQENVSLNTSTCLSSPSIFITPTSDDRKLKRPSSPRSITKSSETSINLIQETPESVESKRRRNVSITSSNSSSPTIWRPF
What is the function of this protein?
Transcription factor (By similarity).  Binds to regulatory DNA sequences in order to modulate transcription; negatively autoregulates its own expression, perhaps dependent upon CBF beta homolog bro-1 (PubMed:18158917).  Promotes proliferation, and prevents differentiation, of seam cells, a stem cell-like lineage, acting in concert with bro-1 (PubMed:31740621).  Required for controlling cell proliferation in the seam cells, perhaps by repressing expression of cyclin-dependent kinase inhibitor cki-1 (PubMed:16236764, PubMed:17933794).  Inhibition of seam cell differentiation is regulated by rnt-1 and bro-1, perhaps acting upstream of pop-1, by antagonizing pop-1 repressor function (PubMed:31740621).  Required for asymmetrical cell divisions in the lineage derived from a posterior embryonic seam cell, the T blast cell, and for asymmetric expression of zinc finger protein tlp-1 (PubMed:16226243).  Regulates growth and male tail development (PubMed:15385167, PubMed:16236764, PubMed:16226243, PubMed:31083672).  Involved in the oxidative stress response, perhaps downstream of the p38 MAP kinase pathway, and acting as part of a negative feedback loop via a transcriptional target gene, tyrosine-protein phosphatase vhp-1 (PubMed:22308034).  Positively modulates dopaminergic signaling in a non-cell autonomous manner (PubMed:31083672).  May be involved in TGF-beta signaling (PubMed:15385167).
What are the official names of this protein?
Runt-related transcription factor rnt-1.
What are the subcellular locations of this protein?
Nucleus. Note=High level of nuclear localization in interphase seam cells before the symmetric larval stage L2 divisions, but subsequently rnt-1 disappears during mitosis, and largely remains absent when the nuclei reform in telophase.
Protein: RBM12_MACMU
Sequence: MAVVIRLQGLPIVAGTMDIRHFFSGLTIPDGGVHIVGGELGEAFIVFATDEDARLGMMRTGGTIKGSKVTLLLSSKTEMQNMIELSRRRFETANLDIPPANASRSGPPPSSGMSGRVNLPTTVSNFNNPSPSVVTATTSVHESNKNIQTFSTASIGTAPPNMGASFGSPTFSSTVPSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVPTLPPVPPVPPIPPVPSVPPMTPLPPMSGMPPLNPPPVAPLPAGMNGSGAPMNLNNNLNPMFLGPLNPVNPIQMNSQSSVKPLPINPDDLYVSVHGMPFSAMENDVRDFFHGLRVDAVHLLKDHVGRNNGNGLVKFLSPQDTFEALKRNRMLMIQRYVEVSPATERQWVAAGGHITFKQNMGPSGQSHPPPQTLPRSKSPSGQKRSRSRSPHEAGFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKATGEGFVEFRNEADYKAALCRHKQYMGNRFIQVHPITKKGMLEKIDMIRKRLQNFSYDQREMMLNPEGDVNSAKVCAHITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQGLGQALVQFKNEDDARKSERLHRKKLNGREAFVHVVTLEDMREIEKNPPAQGKKGLKMPVPGNPAVPGMPNAGLPGVGLPSAGLPGAGLPSTGLPGSAITSAGLPGAGMPSAGIPSAGGEEHAFLTVGSKEANNGPPFNFPGNFGGSNAFGPPIPPPGLGGGAFGDARPGMPSVGNSGLPGLGLDVPGFGGGPNNLSGPSGFGGGPQNFGNGPGSLGGPPGFGSGPPGLGSAPGHLGGPPAFGPGPGPGPGPGPIHIGGPPGFASSSGKPGPTVIKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEAMVAFESRDEATAAVIDLNDRPIGSRKVKLVLG
What are the official names of this protein?
RNA-binding protein 12, RNA-binding motif protein 12, SH3/WW domain anchor protein in the nucleus, SWAN.
What are the subcellular locations of this protein?
Nucleus.