PharMolix/UniProtQA huggingface dataset:
Protein: FZD4_HUMAN
Sequence: MAWRGAGPSVPGAPGGVGLSLGLLLQLLLLLGPARGFGDEEERRCDPIRISMCQNLGYNVTKMPNLVGHELQTDAELQLTTFTPLIQYGCSSQLQFFLCSVYVPMCTEKINIPIGPCGGMCLSVKRRCEPVLKEFGFAWPESLNCSKFPPQNDHNHMCMEGPGDEEVPLPHKTPIQPGEECHSVGTNSDQYIWVKRSLNCVLKCGYDAGLYSRSAKEFTDIWMAVWASLCFISTAFTVLTFLIDSSRFSYPERPIIFLSMCYNIYSIAYIVRLTVGRERISCDFEEAAEPVLIQEGLKNTGCAIIFLLMYFFGMASSIWWVILTLTWFLAAGLKWGHEAIEMHSSYFHIAAWAIPAVKTIVILIMRLVDADELTGLCYVGNQNLDALTGFVVAPLFTYLVIGTLFIAAGLVALFKIRSNLQKDGTKTDKLERLMVKIGVFSVLYTVPATCVIACYFYEISNWALFRYSADDSNMAVEMLKIFMSLLVGITSGMWIWSAKTLHTWQKCSNRLVNSGKVKREKRGNGWVKPGKGSETVV
What is the function of this protein?
Receptor for Wnt proteins (PubMed:30135577).  Most frizzled receptors are coupled to the beta-catenin (CTNNB1) canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin (CTNNB1) and activation of Wnt target genes (PubMed:30135577).  Plays a critical role in retinal vascularization by acting as a receptor for Wnt proteins and norrin (NDP) (By similarity).  In retina, it can be activated by Wnt protein-binding and also by Wnt-independent signaling via binding of norrin (NDP), promoting in both cases beta-catenin (CTNNB1) accumulation and stimulation of LEF/TCF-mediated transcriptional programs (By similarity).  A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase.  Both pathways seem to involve interactions with G-proteins.  May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
What are the official names of this protein?
Frizzled-4, Fz-4, hFz4, FzE4.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor Fz/Smo family.
Protein: CODY_STRPG
Sequence: MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYVKAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLNLQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLGMKGTYLKVINEGIFAKLKEF
What is the function of this protein?
DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability.  During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.
What are the official names of this protein?
Global transcriptional regulator CodY.
What is the protein family that this protein belongs to?
Belongs to the CodY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTCA_XANC8
Sequence: MTAVLPLPLPLADPAPRTPRLQREPLRLAKRLRHAVGQAIADFGMIAPGDKVMVCLSGGKDSYTLLDMLLQLQRSAPVPFTLVAVNLDQKQPDFPADVLPTYLRAQQVPFDIIEQDTYSVVSRVIPQGKTMCSLCSRLRRGALYAYAQAHGVTKIALGHHRDDIVATFFMNLFHHARLAAMAPKLRSDDGAHVVIRPLAYVREADIAAYAQARQFPIIPCNLCGSQENLQRQQVGRMLQQWDREQPGRVDQIARALGDVRPEQLADRTLFDFPGLGGGADAPLPDAAGWLAGSAAEHARD
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPLX1_CAEEL
Sequence: MAGFLMKQMVGNQLSEVTGGLGMKDDGGEKTETGEDPEVIAARLEQEERRKEKHRKMENEREKMRQGIRDKYAIKKKEEGVAMDFTEGRIGGPRKTPEEIAAEMNAEDDSLIGQLGLTEQVEKAKTMATGAFETVKGFFPFGK
What is the function of this protein?
Positively regulates a late step in synaptic vesicle exocytosis.
What are the official names of this protein?
Putative complexin-1.
What is the protein family that this protein belongs to?
Belongs to the complexin/synaphin family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: DCUP_PECCP
Sequence: MTDLKNDRYLRALLRQPVDVTPVWMMRQAGRYLPEYKATRAQAGDFMSLCKNAELACEVTLQPLRRYALDAAILFSDILTIPDAMGLGLYFEAGEGPRFHSPITSHADVVNLPIPDPEQELGYVMNAVRTIRKNLAGEVPLIGFSGSPWTLATYMVEGGSSKAFTVIKKMMFAEPKTLHLLLDKLADSVILYLNAQIRAGAQAVMVFDTWGGALSGRDYKEFSLRYMHKIVDGLQRENEGRRVPVTLFTKGGGQWLEAMAETGCDALGLDWTSDIADARRRVGDKVALQGNMDPSMLYADPARIEQEVASILAGFGQGNGHVFNLGHGIHQDVPPEHAGVFVEAVHRLSRPYHA
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_PECCP
Sequence: MAKLTKRMRVIRDKVDVTKQYDINEAVALLKELATAKFVESVDVAVNLGIDARKSDQNVRGATVLPHGTGRSVRVAVFTQGANAEAAKAAGAEFVGMEDLAEQIKKGEMGFDVVIASPDAMRVVGQLGQVLGPRGLMPNPKVGTVTPNVAEAVNNAKAGQVRYRNDKNGIIHTTIGKVDFDSNKLKENLEALLVALKKAKPSQAKGVYIKKVSLSTTMGAGVAVDQSGLNAAAN
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: PSAA_ARATH
Sequence: MIIRSPEPEVKILVDRDPIKTSFEEWAKPGHFSRTIAKGPDTTTWIWNLHADAHDFDSHTSDLEEISRKVFSAHFGQLSIIFLWLSGMYFHGARFSNYEAWLSDPTHIGPSAQVVWPIVGQEILNGDVGGGFRGIQITSGFFQIWRASGITSELQLYCTAIGALVFAALMLFAGWFHYHKAAPKLAWFQDVESMLNHHLAGLLGLGSLSWAGHQVHVSLPINQFLNAGVDPKEIPLPHEFILNRDLLAQLYPSFAEGATPFFTLNWSKYSEFLTFRGGLDPVTGGLWLTDIAHHHLAIAILFLIAGHMYRTNWGIGHGIKDILEAHKGPFTGQGHKGLYEILTTSWHAQLSLNLAMLGSLTIIVAHHMYSMPPYPYLATDYATQLSLFTHHMWIGGFLIVGAAAHAAIFMVRDYDPTNRYNDLLDRVLRHRDAIISHLNWVCIFLGFHSFGLYIHNDTMSALGRPQDMFSDTAIQLQPVFAQWIQNTHALAPGVTAPGETASTSLTWGGGELVAVGGKVALLPIPLGTADFLVHHIHAFTIHVTVLILLKGVLFARSSRLIPDKANLGFRFPCDGPGRGGTCQVSAWDHVFLGLFWMYNAISVVIFHFSWKMQSDVWGSISDQGVVTHITGGNFAQSSITINGWLRDFLWAQASQVIQSYGSSLSAYGLFFLGAHFVWAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPATQPRALSIIQGRAVGVTHYLLGGIATTWAFFLARIIAVG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PSI-A, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PYRB_RHOJR
Sequence: MKHLLSIADLTRESAVELLDEAERFEQALLGREVRKLPTLRGRTVMTVFFENSTRTRVSFEVAGKWMSADVINVSASSSSVSKGESLRDTAMTLRAAGADALIVRHPASGAAHQIAKWTGHQDDGGPAVINAGDGTHEHPTQALLDALTLRQRLGDIEGKRIAIVGDILHSRVARSNALLLSMLGAEVVLVAPPTLLPVGVSAWPVSVAHSLDAELPGLDAVLMLRVQAERMNGGFFPSQREYSINYGLSEKRLALLPDHAVVLHPGPMLRGMEIASAVADSTRTAVLQQVTNGVHMRMAVLFRLLVGAEEVAG
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: PALC_MAGO7
Sequence: MPYPFVLPTTSAFSFSTSFSCESHPSLPLNASTYRGVVRDTLKKHKRLPPSSQSSSLSLVVASINDYLRYLLAVDAGIAHRSPHGGHGEQIDVVLRSAPAIEWRPFLSDSAVPGKEPPRVRIQSLEHELFFTLSTLASALSLQARAALQPLYVVSVAVPGPEQRLAAITGATKLLLDAASIYDYLSTRSTSLSGPAPCADISPATVSAQRSLALAEATLLAVFKDDPYPTVVAQDRNNLDKDWMFKAPEIPKVRAHLFARLCLAASEHAAQASSLCQAQSSSGGSASGNGGGKMVGLMRNATARGLDGNFIRYIENLRRTARAKACRFFAIDAELGGQTGNAIGWLRAGLQELGVEQREATKKSGGLSLSRFTKEWSEKREDRKVEKGARWGADAGKTEEVRVIEMLDAKWSKQNDTMNIQAVPTPATLLAQMPSGRDMHTVKPYEPPSLDPVVLESMRAPPEGSDDFENASDSEDEGKDNNSRGPVGAFPGTRNEYGRTNSSNSYY
What is the function of this protein?
Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH.
What are the official names of this protein?
pH-response regulator protein palC.
What is the protein family that this protein belongs to?
Belongs to the palC family.
Protein: MIAA_STRR6
Sequence: MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLDIGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTGLYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRALEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHSPNVQAAKGIGYKELFPYFRGEQTFEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIGESGVQDRILSQIEEFLDD
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: PSAA_PROMS
Sequence: MTISPPESGEKNKKVLEDPVKADPRPIDFAKLDKPGFWSSKLSKGPKTTTWIWNLHADAHDFDVHTGDAEEATRKIFSAHFGHLAVIFIWMSAAFFHGARFSNYSGWLADPTHVKPGAQQVWAIVGQEMLNADLGANYNGIQISSGIFHMWRAWGITNESELMALAIGAVVMAALMLHAGIFHYHKAAPKMEWFQDIESMLNHHIAGLVGLGSLAWAGHCIHIGAPTAALLDAIDAGSPLVINGKEIATIADMPMPHQLCDPQIIGQIFPGLASGTGNFFSLNWLAFSDFLTFKGGLNPVTGSLWMTDVSHHHLAFGVIAIIGGHMYRTNYGIGHSMKEILDSQQGDPILFPAPKGHQGLFEFMAESRHAQLSVNLAMLGSISILVSHHMYAMPPYPYIATDYMTVLGLFTHHMWIGGLFIVGAGAHAGIAMVRDYDPAKHIDNVLDRILKARDALISHLNWVCMWLGFHSFGLYIHNDTMRALGRPQDMFSDSAIQLQPIFAQWVQSIQASAVGTFLLAGTSEALPHKALSEVFNGSLVEVGGKVAIAPIPLGTADLMIHHIHAFQIHVTVLILLKGVLYARSSRLIPDKASLGFRFPCDGPGRGGTCQVSSWDHVFLALFWMYNCLSIVIFHFSWKMQSDVWGLTGGNFAQSSITINGWLRDFLWAQASQVLTSYGQSISMYGLMFLGAHFIWAFSLMFLFSGRGYWQELFESIVWAHNKLKVAPTIQPRALSITQGRAVGVTHFLVGGIATTWAFFHARLFGLG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: NAGB_BEUC1
Sequence: MEVVIVPDAADAAALVADTIGALLEREPEPVLGLATGSSPLAVYDELAARYERGEVSFANARAFMLDEYVGLPADHPERYRTVIEREFAGRVDFAPGAVQGPDGTAEDVAAACAAYEQAITASGGVDLQILGIGTDGHIAFNEPGSSLASRTRIKTLTEQTRRDNARFFGGDVDAVPTHCLTQGLATIMAAKHIVLLASGRGKAEAIHHLVEGAVSAMWPATILQHHPHVSVLVDPAAASRLQLADYYRQTYAAKPDWQGL
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: M3K6_MOUSE
Sequence: MAGPCPRAGVLERAGSCWQDPLAEALSRGRSSPAVTGRGCARSRPLSVVYVLTREPGPGVEPGSGTEAEPLPLRCLREACAQLQGTRPPPQLRSLPFATLALGDTAALDSFYNADVVVLEVSSSLAQPSLFYHLGVRESFSMTNNVLLCSQAELPDLQALREDVFQKNSDCVGSYTLIPYVVTATGRVLCGDAGLLRGIADGLVQAGAGTEALLTPLVGRLVRLLEATPTDSCGYFRETIRQDIRQARERFSGQQLRQELARLQRRLDSVELLSPDIVMNLLLSYRDVQDYSAIIELVETLQALPTCDVAEQHNVCFHYTFALNRRNRPGDREKALAVLLPLVKYEGPVAPDLYCMCGRIYKDMFFTSGFQNAGHLEQAYHWYRKAFDVEPSLHSGINAAVLLIAAGQHFEDSEELRLIGMKLACLLARKGCVEKMQYYWDVGFYLGAQILANDPIQVVLAAEQLYKLNAPIWYLVSVMETFLLYQHFRPTPEPSGGPPLRAHFWLHFLLQSCQPFKMAPPQEDQCLVLVLEINKVLLPARLEIQGTDPMSAVTLSLLEPETQEDPSSWTFPVTSICGISTSKLDQRCCFLYALPPAQDVQLCFPSVERCQRFCGLIQVLVMNPDSSAPTEEAEGAREVLEFDYEYSETGERLVLGRGTYGVVYAGRDRHTRVRIAIKEIPERDSRFSQPLHEEIALHKRLRHKNIVRYLGSASQGGYLKIFMEEVPGGSLSSLLRSVWGPLKDNESTISFYTRQILQGLSYLHENRIVHRDIKGDNVLINTFSGLLKISDFGTSKRLAGITPCTETFTGTLQYMAPEIIDQGPRGYGKAADIWSLGCTVIEMATGRPPFHELGSPQAAMFQVGMYKVHPPVPGSLSAEAQAFLLRTFEPDPRLRASAQELLGDPFLQPGKRSRSPGSPRHTPRPSGAPSGPSSPSADSATQSQTFPRPQAPSQHPPSPPKRCLSYGDTSQLRVPEEPAAEEPASPEESSGLSLLHQESKRRAMLAAVLEQEVPTLAENLLEQEQDSRLSKIHVELLLRCLGAQIHTPNRRQLAQELRTLQAQLRAQSLGPALLKGPLFAFPDAVKQILRRRQIRPHWMFVLDSLLSRAVRAALAVLDAESEKKAVLPRSEESSKEESQQKPQESQALQSQLPPEQGPPSLMVELGLLRAETDRLRDLLAEKERECQALVQQALHRVHAETRKYAPASETPATLPKDQNLVRWLQELSVDPATIQTLLSHSFTLQTLLTCATQDDLVYTRIRGGMVCRIWRAILAQRAGATSVTPVPRDAE
What is the function of this protein?
Component of a protein kinase signal transduction cascade.  Activates the JNK, but not ERK or p38 kinase pathways.
What are the official names of this protein?
Mitogen-activated protein kinase kinase kinase 6, Apoptosis signal-regulating kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
Protein: SAMTR_CHICK
Sequence: MEAAPRSRPRPGGAAASPPPPPPPPPPEQERKLEQEKLSGVVKSVHRRLRKKYREVGDFDKIWREHCEDEETLCEYAVAMKNLADNHWAKTCEGEGRIEWCCSVCREYFQNGGKRKALEKDEKRALLASKSTPALNASQPPKIEDPLPNFGLTNHEAITEELLHSLGKIRLLDVGSCFNPFLKFEEFLTVGIDIVPAVESVYKCDFLNLQIQQPLQLAQDAIDAFLKQLKNPIDSLPGELFHVVVFSLLLSYFPSPYQRWICCKKAHELLVLNGLLLVITPDSSHQNRRAMMMKSWKIAIESLGFKRFKYSKFSHMHLMAFRKTSLQTTSDLVSRNYPGMLYIPQDFNSIEDEEYSNTSCYIRSDMEDEQLAYGFMELPDAPYDSDSGESQSSSIPFYELEDPVLLLS
What is the function of this protein?
S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes.  Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling.  Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 signaling.  Probably also acts as a S-adenosyl-L-methionine-dependent methyltransferase.
What are the official names of this protein?
S-adenosylmethionine sensor upstream of mTORC1, Probable methyltransferase BMT2 homolog.
What is the protein family that this protein belongs to?
Belongs to the BMT2 family.
Protein: RL4_SERP5
Sequence: MELVLKDAQSALTVSETTFGRDFNEALVHQVVVAYAAGARQGTRAQKTRAEVTGSGKKPWRQKGTGRARSGSVKSPIWRSGGVTFAAKPQDHSQKVNKKMYRGALKSILSELVRQDRLIIVEKFSVEAPKTKLLAQKLKDMALEDVLIVTGELDENLFLAARNLYKVDVRDVAGIDPVSLIAFDKVVMTADAVKQVEEMLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: PUR5_XYLFT
Sequence: MTTPPPPSTTPLTYRDAGVDIDAGNALVERIKPLVKRTFRPEVMSGLGGFGALFNLAGKYKEPVLVSGTDGVGTKLKLAQQLNRHNTIGIDLVAMCVNDVLVQGAEPLFFLDYFATGKLDIDTATAVISGIALGCEQSGCALIGGETAEMPDMYPPGEYDLAGFCVAAVEKSQLLDGSQVREDDVLIGIASSGPHSNGYSLIRRIYERAGSPADLDIHGTRLIDTLMAPTALYVKPILKLLHTHSDAIHAMAHITGGGLTENIIRVIPPNLGLRIDANAWTQPPVFQWLQREGALADTEMWRTFNCGIGFVLVATPNQVAPLGQALDNQGLAHWQIGRVVTPVDNERVHIG
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOAC_COREF
Sequence: MSELTHVRADGSAHMVDVTAKAETSRTAVAEGFVRTRADVVDKLFTADLPKGDALPVARVAGIMGAKKTPEIIPLCHPLPLGKITVDFERLPDGVRIEASVKTRGVTGVEMEALTAVTTAALTVYDMIKAVDKMAVIDGVRVLAKTGGKSGDWSV
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: BIOB_SALTI
Sequence: MARHPRWTLSQVTELFEKPLLELLFEAQQIHRQHFDPQQVQVSTLLSIKTGACPEDCKYCPQSSRYKTGLEAERLMEVEQVLDSARKAKNAGSTRFCMGAAWKNPHERDMPYLEKIVQGVKAMGLETCMTLGMLNESQAQRLANAGLDYYNHNLDTSPEFYGNIITTRTYQERLDTLEKVREAGIKVCSGGIVGLGETVTDRAGLLLQLANLPTPPESVPINMLVKVKGTPLADNDDVDAFDFIRTIAVARIMMPTSYVRLSAGREQMNEQTQAMCFMAGANSIFYGCKLLTTPNPAEDKDLQLFRKLGLNPQQTRVLAGDNEQQQRLEQTLMTPDTDDYYNAAAL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: NRDR_NITMU
Sequence: MKCPFCHTPDTSVIDSRVSEEGDRIRRRRRCPHCDKRFTTYETVELRLPQVVKQDGNRAEFDREKLRTGFVRALHKRPVSAEDVEAAMNRVVQKLLSLGEREIASHKIGEMVMGELYKLDKVAYIRFASVYRSFQGAADFDDAIRELQGSDSRKEPDKP
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: RNC_NITEU
Sequence: MTSSRPIAHNTKNKQTKTLKGRDYAVFLQKLGYTFKQPDLLREALTHRSLGFPNNERFEFLGDSVLNCAVSTLLFKRFPSLPEGDLTRLRANFVNQQALHRLASALGIGELILLGEGERKSGGHHRPSILANAVEAIIGAIYLESGFAVVEQVIVALYEPLIRQLDPDTSGKDSKTLLQEYLQSRKIALPEYSVLLAQGDPHAQVFHVECVIPGFGIRTRGEGTSRRRAEQEAARQAYELAIVRH
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSGA_CLOTE
Sequence: MQGIITKGIGGFYYIKTEDGLYECKARGKFRLDELTPMVGDKVEIEIDNNSKGTIEKIFERKNKLIRPAVSNISQAIIVFAFKNPNINLDLLNKFLLQCEYNEINAVVAFNKVDLVENPEKEEVVDIIKSAGYEVIYLNAKEGMGIEKIREKLKGNLNVLCGPSGAGKSTIINKLVGKDVMETGQISEKLKRGKHTTRHSELIEVEDGFLVDTPGFSSLSIEDIEKEEIQFLFPEFIKYINGCKFTGCLHYKEPSCVVKNALEQGKIHKKRYEFYIQIIEEKLRGKNNKW
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNRD_STRGJ
Sequence: MSEQIAAVRRMVEAYNTGKTDDVADYIHPEYMNPGTLEFTSLRGPELFAINVAWVKKTFSEEARLEEVGIEERADWVRARLVLYGRHVGEMVGMAPTGRLFSGEQIHLLHFVDGKIHHHRDWPDYQGTYRQLGEPWPETEHRRP
What is the function of this protein?
Involved in the biosynthesis of aklavinone which is an important precursor common to the formation of the clinically significant anthracyclines such as carminomycin, daunorubicin (daunomycin), rhodomycin, aclacinomycin T (aklavin) and aclacinomycin A (aclarubicin).  These compounds are aromatic polyketide antibiotics that exhibit high cytotoxicity and are widely applied in the chemotherapy of a variety of cancers.  Catalyzes the cyclization of aklanonic acid methyl ester to yield aklaviketone.  It is also able to use nogalonic acid methyl ester as substrate, but produces exclusively auraviketone with C9-R stereochemistry.
What are the official names of this protein?
Aklanonic acid methyl ester cyclase AcmA, AAME cyclase, Methyl aklanonate cyclase.
What is the protein family that this protein belongs to?
Belongs to the polyketide cyclase DnrD family.
Protein: CSPA_YEREN
Sequence: DKGFGFITPADGSKDVFVHFSAIQSNDFKTLDEGQKVEFSIENGAK
What are the official names of this protein?
Major cold shock protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFR3_KLULA
Sequence: MGFLFTPKHQKLVNQCYPPGRTPDKKPKGSETSYLLYYVNSRRPKLEKVSSYLVKRSTTDLNRRRSGNVSVTLELLAKIVENCNENMNIFIKDFIHIMTLVLNNNNFNNDPTIVGLIERVLEAICNHLDGSLVSGDSEFLELFKNFVTLYFKVANTKLNDTDLVLKGCLDFSKISNLGSIHQWSATAKNCVSIALTKFQERHPIYSEATIDSSFSEPGSPALKKKLTRTQTKVMGLDDVSNTGDYSILALNTFFNTTETDKLTIGLHALIEHLLETPNKELLQFICNGIPVQLRYIVILLFVRPLGTSSEKNMLLILKLISSLLTSAVSIIGLSVIDILRRLITVQLAKSDSTTVVKQIAVTIKDLNRKTYYKQQSSDMFAELSFKFIESGKPHHLELFQLDLDSLISVTSDQCLDLDLFGEFLPYVTDKTQLSKLLYPEAPHQVIFIRFFEKVSTLSKQDTEIAISTSFAYYKAASLLSGLAYYVNNNRPSDGYYAYHHHASKFLGLADYQTQVEFKRKDNDIFTKEDLLNYYSDAGSNIYSEKGRDILLVDHSDQNGTDIDQDTVRYSTPIPLPQISIPPTTTNGIGIKKSSPANDTYVTRSLKHNPVPNVKDLKNLVSSKKDKSNTKTLRGSQSVKSKVTNITFLLDELKNDGDEIKIADPDEEDIIGMEKQDLARSYSLRMNTISSTNSRTLIPSVENAEEHGDDFRDAHEDIEVSSSTRGRLFMV
What are the official names of this protein?
Protein EFR3.
What is the protein family that this protein belongs to?
Belongs to the EFR3 family.
Protein: RS9_BRUAB
Sequence: MAESINSLEELGTVAKTEAAAPVHVQKLDAQGRAYATGKRKDAVARVWVKPGTGKITVNDKEFEKYFARPVLQMILQQPIVASNRAGQFDIVATVAGGGLSGQAGAVRHGISKALTDYEPGLRTVLKKGGFLTRDSRVVERKKYGKAKARRSFQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: AMPA_BUCBP
Sequence: MRYHISTNFFKKKYSDCLVFGIFDDLQLCESVKVIDSGSDGYVSRLIKDNEISGQINESLLLHSIPNFQKLKILFLGCGKKERFNINLYQKLFKTSINIIKKLSVKALIYFVTDFHIKNINTYWKIRHAVSEIQDNLYSFKNFKTSNNKNKFKISLEDIYFYLSDHDEINSGNNAIQHGYAISKGKKIARDLSNMPPNICNSSYLADQAMKLSQYYPDLIDVEIINDIDMNKLGMNAYLSVGKGSKNKSLMSIIKYHGISFSQCKNIILIGKGVTFDSGGISIKTSRDLDEMKFDMSGAAIVFGLMSIISDLKLPLNIIGILAGSENMVSSMSFRPGDILTTMSGKTVEILNTDAEGRLILCDVLTYVERFSPEVVIDIATLTGACVVALGHHTTGLLSNNDILAKDLQKASKQTRDLIWRMPLFEEYYKDLDSNVADMANVGTNSAGMITAACFLSKFSQKYAWAHLDVAGTAWISGKNKGSTGRPINLLTQFLLNKLYK
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.