PharMolix/UniProtQA huggingface dataset:
Protein: UPPP_ECOLU
Sequence: MSDMHSLLIAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDTAKTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGRPLQHEGESKGRLTLIHILLGMIPAVVLGLLFHDTIKSLFNPINVMYALVVGGLLLIAAECLKPKEPRAPGLDDMTYRQAFMIGCFQCLALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATALDLYKSWGFLTTGDIPMFAVGFITAFVVALIAIKTFLQLIKRISFIPFAIYRFIVAAAVYVVFF
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SPX4_ORYSJ
Sequence: MKFGKDFRSHLEETLPAWRDKYLAYKSLKKLIKNLPPDGDPPPVAAAAEVPAGDGDGDGGIALGNWFARVLDMELQKLNDFYIEREEWYVIRLQVLKERIERVKAKKNGAFTSKSEFTEEMLEIRKAFVIIHGEMILLQTYSSLNFAGLVKILKKYDKRTGGLLSLPFTQRARHQPFFTTEPLTRLVRECEANLELLFPIEAEVLESASSSAKLQPQNDDAASHDPASSVDVETSDVYRSTLAAMKAIQGLRKASSTYNPLSLARFFHGEDGEACSGAITSESDSYSDSQIEDAEDDDKEVQSREQNTAQNAAEGQPRDE
What is the function of this protein?
Inositol polyphosphate sensor that associates with transcription factors to regulate Pi starvation responses (PubMed:27080106).  The SPX domain provides a basic binding surface for inositol polyphosphate signaling molecules (PubMed:27080106).  Interacts with PHR2 to inhibits its translocation to the nucleus and repress its DNA-binding activity, and then negatively regulate Pi signaling (PubMed:24692424).
What are the official names of this protein?
SPX domain-containing protein 4, Protein SPX DOMAIN GENE 4, OsSPX4.
What are the subcellular locations of this protein?
Membrane. Nucleus. Cytoplasm. Note=Unlike PubMed:19566645, PubMed:24692424 cannot find a membrane localization.
Protein: RL16_AZOSB
Sequence: MLQPSRRKYRKEQKGRNTGLATRGTKVSFGDFGLKAIARGRLTARQIESARRAMTRHIKRGGRIWIRIFPDKPISKKPAEVRMGNGKGNPEYWVAEIQPGKVLYEMDGVDEALAREAFRLAAAKLPLETVFVTRQVG
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: TSAD_FRATW
Sequence: MIVLGIESSCDETGLAIYDYSKKKLIADELYSQVKLHKKYGGVVPELASRKHIAKLNLLAKKIFKETGLSFEDIDCIAYTAMPGLVGALMVGATFAKTLGLIHNIDTIAVHHLEGHLLSPLLDHNSNIEYPFVALLVSGGHTQLFEVKEFGEYSLLGESIDDAAGEAFDKTTKLLGMGYPGGVEVANLADQATDKSKYILPRPMKNKPNLDFSFSGLKTAVLNTWYDEQDQSLENKANLCYAFQDAAIDVLVSKCAKALQKTKNTRLVISGGVSANKLLRHQLDLLAKNRGYQIFFPPMKYCTDNGAMIALAGAYRYVNGFKDSNLEINVKARSPL
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSD2_CHRSD
Sequence: MLSPERQTHLKQLEAESIHIIREVAAEFANPVMLYSIGKDSSVMLHLARKAFYPGTPPFPLMHVNTTWKFKEMIEFRDRMAAEVGMELIEHINEEGRAAGINPFDHGSAKYTDVMKTQSLKQALDKYGFDAAFGGARRDEEASRAKERVYSFRDKHHRWDPKSQRPELWNIYNGKVQKGESIRVFPLSNWTELDIWQYIYLESIPIVPLYYAAPRPVVERDGMQIMVDDERLPLEDGEVPEEKWVRFRTLGCYPLTGAVESTAATLPEIIQEMLLTRTSERSGRAIDHDQAGSMERKKREGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2 2, ATP-sulfurylase small subunit 2, Sulfate adenylate transferase 2, SAT 2.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: NADD_KINRD
Sequence: MGGTFDPIHHGHLVAASEVAARFALDEVVFVPTGKPWQKSRVDIAPAEHRYLMTVIATASNPRFTVSRIDIDRGGFTYTIDTLRELRDLRPEADLFFITGADALAQILQWKDVAELWSLAHFVGVSRPGHALTDDGLPLDGVSLMEVPALSISSTDCRQRVAEGLPVWYLVPDGVVQHISKHRLYTAPEHGRLLDARGEALAVGESGD
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: TMC5A_HUMAN
Sequence: MEISRLAQSKRNIISLNMDLERDTQRIDEANQKLLLKIQEREDKIQRLESEIIQTRGLVEDEEWEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSPDGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEELEALFLEREVSKLVSMNPVEKEHTSQNNEGTPTQKTARLFSKKIFCCLFFITLFFIRLLSYMFFHVRFINPDLLVNVLPKVLGRSTLWKLRCFFFPSLTLETEDMLPH
What are the official names of this protein?
Transmembrane and coiled-coil domain-containing protein 5A.
What is the protein family that this protein belongs to?
Belongs to the TMCO5 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ATP1_ARATH
Sequence: MAATSSSPPCNISASSLLLRQPSRSILKVFGLLPPVSRNNRKLGRLTVTRSNLAQDFLGDFGARDPYPEEIASQFGDKVLGCQSTEHKILIPNASVLSLSQLQCSPVSSSQPPLSGDDARTLLHKVLGWSIVDNEAGGLKIRCMWKVRDFGCGVELINRIHKVAEASGHYPSLHLESPTQVRAELFTSSIGGLSMNDFIMAAKIDDIKTSDLSPRKRAWA
What is the function of this protein?
Involved in tetrahydrobiopterin biosynthesis (By similarity).  Interacts with and acts downstream of the E3 ubiquitin-protein ligase SDIR1 in abscisic acid (ABA) and salt stress signaling.  Regulates the expression of the bZIP transcription factor ABI5, which mediates responses to ABA during seed germination and salt stress.  The SDIR1-ATP1/SDIRIP1 complex plays an important role in ABA signaling through the ubiquitination pathway (PubMed:25616872).  Acts downstream of AIRP2 in regulation of ABA signaling during drought stress (PubMed:28626006).
What are the official names of this protein?
Probable pterin-4-alpha-carbinolamine dehydratase, chloroplastic, 4-alpha-hydroxy-tetrahydropterin dehydratase, PCD/DCoH-like protein 1, Protein AIRP2 TARGET PROTEIN 1, Protein SDIR1-INTERACTING PROTEIN 1.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
What are the subcellular locations of this protein?
Plastid, chloroplast. Cell membrane; Peripheral membrane protein. Nucleus.
Protein: RPOC2_PHAAO
Sequence: MEVLMAERTNLVFHNKVIDGTAIKRLISRLIDHFGMAYTSHILDQVKALGLRRATATSISLGIDDLLTIPSKRWLVQDAEQQSFLLEKNHHYGNVHVVEKLRQSIEVWYATSEYLRQEMNPNFQMTDPSNPVHLMSFSGARGNASQVHQLVGMRGLMSDPQGQMIDLPIQSNLREGLSVTEYIISCYGARKGVVDTAVRTSDAGYLTRRLVEVVQHILVRRTDCGTIRGISVSPQNGMTEKIFVQTLIGRVLADDIYIGLRCIGTRNKDIGIGLVNRFITFQAHPIYIRTPFTCRSTSWICQLCYGRSPTHGDLVELGEAVGIIAGQSIGEPGTQLTLRTFHTGGVFTGGTAEHVRAPSNGKIKFDEGLVHPTRTRHGHPAFLCFIDFYVTIESRDIRHNVNIPTKSLILVQNDQYVESEQVIAEIRAETSTFHFKERVQKHIYSESEGEMHWSTDGYHTPKYPYSNVHLLPKTSHLWILAGGLCRSNSNIVSFSLHKDQDQMNANSFSLKDLFDLSLTNDQVRHKLLDTFGKKDRESLDYSKPYRIISKGHWNLIEPSTYIRQENSLAKKRRNRFVIPLQYDQEQENKLIPCFGISIKIPINGILRRNSIIAYFDDPRYRRSSSGITKYGIVEVDSIVKKEDLIEYRGAKDFSPKYQTQMKVDQFFFIPEEIHILPGSSPIMVRNNSIIGVDTRLVLNINTRSRVGGLVRVERKKKSLELKIFSGDIHFYGEVDKISRHSGILIPPGIGKKDSKGSKKLKNWIYVQRITPTKKKYFVLVRPVVTYEIADGINLATLFSQDLLQEKNNVQLRIVNYILYENGKSIRGISHTSIQLVRACLVLTWDQEKKSSIEEKVHASFVEIRTNDLLCYFIRIELVKSTLSYTEKRYDTAGSGLISNNELDRIHRKNPFDSKAKIQIFPQHQGTLGTLLNRNKECQSFLILSSSNCSRIGPFNTSRYNNATKELDPMTPIRYLLGPLGTIVPRIVNSRSSYYLRTYNQVFLKKSFLLENFQQTFQVLQVPPFQYCFLDENSRIYNPDPCSNIIWNSFHLNWCFLHHDSCEEAWPIISLGQFLCENVYLLKYGSRIKKSGQIFIVHVDSLVIRSAKPYLVTPGATVHGHYGETFYEGDTLITFIYEKSRSGDITQGLPKVEQILEVRSIDSISMNLERRVEGWDERIRRILGIPWGFLIGAELTIAQSRISLVNKIQKVYRSQGVQIHNRHLEIIVRQVTSRVLVSEDGMSNVFLPGEFIGLLRAERAGRVLAESICYRAILLGITKSSLNTQSFISEASFQETARVLAKAALRGRIDWLKGLKENVVLGGIIPVGTGFNKLVHRSKQDKNIHLKIKRKNLFELEMSDILLHHRELFCSCAQELSMRHQTNLLRNVS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta'', PEP, Plastid-encoded RNA polymerase subunit beta'', RNA polymerase subunit beta''.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: AROD_STAAR
Sequence: MTHVEVVATITPQLYIEETLIQKINHRIDAIDVLELRIDQFENVTVDQVAEMITKLKVMQDSFKLLVTYRTKLQGGYGQFTNDSYLNLISDLANINGIDMIDIEWQADIDIEKHQRIITHLQQYNKEVIISHHNFESTPPLDELQFIFFKMQKFNPEYVKLAVMPHNKNDVLNLLQAMSTFSDTMDCKVVGISMSKLGLISRTAQGVFGGALTYGCIGEPQAPGQIDVTDLKAQVTLY
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: MURA_PSEA7
Sequence: MDKLIITGGNRLDGEIRISGAKNSALPILAATLLADTPVTVCNLPHLHDITTMIELFGRMGVQPIIDEKLNVEVDASSIKTLVAPYELVKTMRASILVLGPMLARFGEAEVALPGGCAIGSRPVDLHIRGLEAMGAQIEVEGGYIKAKAPVGGLHGGQFFFDTVSVTGTENLMMAAALANGRTVLQNAAREPEVVDLANCLNAMGANVQGAGSDTIVIDGVKRLGGARYDVLPDRIETGTYLVAAAATGGRVKLKDTDPTILEAVLQKLEEAGAHINTGNNWIELDMKGNRPKAVNIRTAPYPAFPTDMQAQFISMNAVAEGTGAVIETVFENRFMHVYEMNRMGAQILVEGNTAIVTGVPRLKGAPVMATDLRASASLVIAGLVAEGDTLIDRIYHIDRGYECIEEKLQLLGAKIRRVPG
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CNGA4_RAT
Sequence: MSQDGKVKTTESTPPAPTKARKWLPVLDPSGDYYYWWLNTMVFPIMYNLIIVVCRACFPDLQHSYLVAWFVLDYTSDLLYLLDIGVRFHTGFLEQGILVVDKGMIASRYVRTWSFLLDLASLVPTDAAYVQLGPHIPTLRLNRFLRVPRLFEAFDRTETRTAYPNAFRIAKLMLYIFVVIHWNSCLYFALSRYLGFGRDAWVYPDPAQPGFERLRRQYLYSFYFSTLILTTVGDTPLPDREEEYLFMVGDFLLAVMGFATIMGSMSSVIYNMNTADAAFYPDHALVKKYMKLQHVNKRLERRVIDWYQHLQINKKMTNEVAILQHLPERLRAEVAVSVHLSTLSRVQIFQNCEASLLEELVLKLQPQTYSPGEYVCRKGDIGREMYIIREGQLAVVADDGVTQYAVLGAGLYFGEISIINIKGNMSGNRRTANIKSLGYSDLFCLSKEDLREVLSEYPQAQAVMEEKGREILLKMNKLDVNAEAAEIALQEATESRLKGLDQQLDDLQTKFARLLAELESSALKIAYRIERLEWQTREWPMPEDMGEADDEAEPGEGTSKDGEGKAGQAGPSGIE
What is the function of this protein?
Second messenger, cAMP, causes the opening of cation-selective cyclic nucleotide-gated (CNG) channels and depolarization of the neuron (olfactory sensory neurons, OSNs).  CNGA4 is the modulatory subunit of this channel which is known to play a central role in the transduction of odorant signals and subsequent adaptation.  By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation to odor stimulation and extends its range of odor detection (By similarity).
What are the official names of this protein?
Cyclic nucleotide-gated cation channel alpha-4, Cyclic nucleotide-gated channel alpha-4, CNG channel alpha-4, CNG-4, CNG4, Cyclic nucleotide-gated olfactory channel subunit OCNC2.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family. CNGA4 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RIPL1_MOUSE
Sequence: MEEPLGSPPAALSALEKNVAELTVMDVYDIASLVGHEFERVIDQHGCESIARLMPKVVRVLEILEVLVSRHHVAPELDELRLELDRLRVERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLNHKDVGFSEEEFQKQEGMSERERQVMKRLKEVVDKQRDELRAKDRELGLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEEEAEIQPQPDGEESISDAEKAALDLKDPNRPRFTLQELRDVLHERNELKSKVFLLQEELAYYKSEEIEEENRIPQPPPITHPRTSPQPESGIKRLFSFFSRDKKRLANTQRPTHIHESFGQWAITQRDDGYTEQGQEALQHL
What is the function of this protein?
Neuroprotective protein, which acts by sequestring GAPDH in the cytosol and prevent the apoptotic function of GAPDH in the nucleus (By similarity).  Competes with SIAH1 for binding GAPDH (By similarity).  Does not regulate lysosomal morphology and distribution (By similarity).  Plays a role in the regulation of cell shape and polarity (PubMed:23264467).  Plays a role in cellular protein transport, including protein transport away from primary cilia (PubMed:23264467).  Binds to RAB10 following LRRK2-mediated RAB10 phosphorylation which leads to inhibition of ciliogenesis (By similarity).
What are the official names of this protein?
RILP-like protein 1, Rab-interacting lysosomal-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the RILPL family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell projection, cilium. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole.
Protein: SYN_YERPN
Sequence: MSVVPVVDVLQGRAAVGSEVTVRGWVRTRRDSKAGISFVAVYDGSCFDPLQAVVNNTLPNYQDEVLHLTTGCSVEVTGTVVASPGEGQSFEIQATAINVVGWVDDPDTYPMAAKRHSIEYLREVAHLRPRTNLIGAVARVRHTLAQAIHRFFDENGYFWVSTPLITASDTEGAGEMFRVSTLDLENLPRTDTGAVDFSEDFFGKEAFLTVSGQLNGETYACALSKVYTFGPTFRAENSNTSRHLAEFWMVEPEVAFASLDDVAGLAEKMLKYVFQAVLNERADDMKFFAERVDKDAVDRLQRFVTSDFAQVDYTDAIEILLASGQKFENDVSWGIDLSSEHERYLAEKHFKAPVVVKNYPKDIKAFYMRMNEDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDARLAEMGLNKEDYWWYRDLRRYGTVPHSGFGLGFERLISYVTGVQNVRDVIPFPRTPRNASF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OSER1_RAT
Sequence: MKSEAKDGEEESLQTAFKKLRVDASGSIVSLSVGEGTSVRASVRTTVDDTKPKTMCAPKDSWHGSTRKSSRGAVRIQRRRRSKSPVLHPPKFIHCSTTASPSSSQLKQRSQTEPLDGSSGRGISTPKEFSTGENSTSLDINHTGAAIEPLRSSVLRLPSESKTEELSDATQVSPESLTANDLSDFQSVSKLSQGKPCVCVGKACQCKRWHDMEVYSFSGLQNVPPLAPERRSLEDYSQSLHTRTLSGSPRSCSEQARVYVDDVTIEDLAGYMEYYLYIPKKMSHMAEMMYT
What are the official names of this protein?
Oxidative stress-responsive serine-rich protein 1, Oxidative stress-responsive protein 1, Peroxide-inducible transcript 1 protein.
Protein: QRCD_DESVH
Sequence: MDKNYNLPVDAELFPEGCERCSLSKFMMWMAFVFVFFGWGLYAAYRVLAEGLGVTGLDDYFGFGLWITFDLAVIALGAGAFFSGLLRYILNIDPLKNIINLAVIIGFLCYSGAMLVLVLDIGQPLRAWFGYWHANVHSMLTEVIFCITCYCLVLIIEYVPLILENRQLNKNKLVHAVAHNFHVMMPLFAGIGAFLSTFHQGSLGGMYGVLFGRPYIYREGFFIWPWTFFLYVLSAVGSGPVFTVLVCTLMEKMTGRKLVSWEVKSLMGKIAGTMLMVYLIFKFADTYAWAYDLLPRQGLTFDQMFTSGWIYGKWMLWAELFYCGLVPAIILIVPALRNNPVLFYSAAILDCIGITINRYVMTVQALAIPVMPFDSWESYLPNWAEWGASVMIVAYAALVLSLSYRYLPIFPQEAELNRK
What is the function of this protein?
Component of the respiratory Qrc complex, that catalyzes the reduction of the menaquinone pool using electrons transferred from the reduced periplasmic cytochrome c3, and which is probably involved in sulfate respiration.  Is likely essential for growth on H(2) or formate since the periplasmic hydrogenases and/or formate dehydrogenases act as primary electron donors for the Qrc complex.  The QrcD subunit anchors the protein complex to the membrane and likely interacts with the quinone pool.
What are the official names of this protein?
Menaquinone reductase, integral membrane subunit, Quinone reductase complex subunit D, Type I cytochrome c3:menaquinone oxidoreductase subunit D.
What is the protein family that this protein belongs to?
Belongs to the NrfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LUXS_ECOL5
Sequence: MPLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPNKEVMPERGIHTLEHLFAGFMRNHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVADAWKAAMEDVLKVQDQNQIPELNVYQCGTYQMHSLQEAQDIARNILERDVRINSNEELALPKEKLQELHI
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: VP2_SMSV4
Sequence: MNYANFGLDFLNSVANAVVEGKKLDLASKGLQLKSRALDTERAFNYDRLAFEKHKFETNNDLKIYGDAMRISALRAAGLRINPYSNGRQIYQDEADLANLHSYYSFYKTD
What is the function of this protein?
Minor structural protein present in one or two copies per virion.  Does not seem to play a role in capsid assembly, but is essential for production of infectious virus (By similarity).
What are the official names of this protein?
Protein VP2, Minor capsid protein.
What is the protein family that this protein belongs to?
Belongs to the vesivirus VP2 protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: Y1451_METJA
Sequence: MGIFDVISGLFKKKPKIAYAKSQSVDLIELKRNPYYIVASVELGNTTTKSIITATNMDTGKTYIVSKHVKMTRDVRKPKKGEEVFGETLWGVELTREAVADMVKEVLLESLKKAGLTVDDLHFVVRSTGVTAGFASPEEVGEMIIALAQGCMKAGVPPAKMTPAMTKEQIPKPFDKYSFLDKIIFDGAVTGVLPPTGKEVVANEMEGELVTAGIKVGSKWTDVDFRNPCMSIDFGTTLAGRITNDTLPYAKVIGNLCGLAGAIADAIARGSGKIDEKTGAALDLANIKGKPNEELAKEYAEEMHKYIIIKEVPKDVDRFGTVPVDPKSAEKAGTTLIGCDVGKNGSDLIKLEELGRELVEKSDIPTLMCCLDYVMSEVVRRLVELAYKKGLISEKSAVGITGRAGITGRKPELIIEKLKTLEIWDKVEENVVFVEDGLALGASVMARCMNCLGTPQVPIGGVRGGGCILGLRRKWQKERGMIRD
What are the official names of this protein?
Uncharacterized protein MJ1451.
What is the protein family that this protein belongs to?
To M.thermoautotrophicum MTH1153.
Protein: PADE_AROEV
Sequence: MYEVRFHGRGGQGSVMASGMLAAAMVEEGKYAVSIPSFGFERRGAPVVSFLRMSDREIRQLTNIYQPDCIVCVDPTLTKSVDIFAGMKAGGTLVQATHHPLSELALPDCVSTVGLLDAVKIALEIFKRPITNTLMLGAFAKTTGVVSLESLKRALEDSEFRDAGLAQNMTALERGYAEVAVHHIERRAAA
What is the function of this protein?
Involved in the anaerobic metabolism of phenylalanine and phenylacetate.  Catalyzes the oxidative decarboxylation of phenylglyoxylate to benzoyl-CoA and CO(2).  It can also react slowly with 2-oxo-3-methylbutanoate and use different electron acceptors such as benzyl viologen, methyl viologen, FAD or FMN, but NAD seems to be the physiological electron acceptor.  Also catalyzes an isotope exchange between CO(2) and the carboxyl group which proves partial or complete reversibility of the oxidative decarboxylation reaction.
What are the official names of this protein?
NADH-dependent phenylglyoxylate dehydrogenase subunit gamma, Phenylglyoxylate:NAD oxidoreductase, Phenylglyoxylate:acceptor oxidoreductase.
Protein: MAFB_CHICK
Sequence: MAGELSIGAELPTSPLAMEYVNDFDLMKFDVKKEPLGRNDRSGRHCTRLQPAGSVSSTPISTPCSSVPSSPSFSPTEQKTHLEDLYWMANSYQQMNPEALNLTPEDAVEALIGSHQVSQQLQGFESFRAHHHHHHHHHQHHHQYPAVTHEDLAGSGHPHHHHHHHHQASPTPSTSSSSSQQLQTSHQQHPPSSSVEDRFSDDQLVSMSVRELNRHLRGFTKDEVIRLKQKRRTLKNRGYAQSCRYKRVQQKHHLENEKTQLIQQVEQLKQEVTRLARERDAYKLKCEKLASNGFREAGSTSDNPSSPEFFM
What is the function of this protein?
Acts as a transcriptional activator or repressor.  Positively regulates the expression of alpha-A crystallin genes during lens fiber cell differentiation.  Binds to Maf recognition elements (MARE).
What are the official names of this protein?
Transcription factor MafB, Maf-B, V-maf musculoaponeurotic fibrosarcoma oncogene homolog B.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. Maf subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PIT_MYCTO
Sequence: MNLQLFLLLIVVVTALAFDFTNGFHDTGNAMATSIASGALAPRVAVALSAVLNLIGAFLSTAVAATIAKGLIDANLVTLELVFAGLVGGIVWNLLTWLLGIPSSSSHALIGGIVGATIAAVGLRGVIWSGVVSKVIVPAVVAALLATLVGAVGTWLVYRTTRGVAEKRTERGFRRGQIGSASLVSLAHGTNDAQKTMGVIFLALMSYGAVSTTASVPPLWVIVSCAVAMAAGTYLGGWRIIRTLGKGLVEIKPPQGMAAESSSAAVILLSAHFGYALSTTQVATGSVLGSGVGKPGAEVRWGVAGRMVVAWLVTLPLAGLVGAFTYGLVHFIGGYPGAILGFALLWLTATAIWLRSRRAPIDHTNVNADWEGNLTAGLEAGAQPLADQRPPVPAPPAPTPPPNHRAPQFGVTTRNAP
What is the function of this protein?
Low-affinity inorganic phosphate transporter.
What are the official names of this protein?
Probable low-affinity inorganic phosphate transporter.
What is the protein family that this protein belongs to?
Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. Pit subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FLIW_DESVH
Sequence: MARQNEIEIQTRIGRQRITLDKIIHFPRGLAGFEGRHDFTLLQLREGAPFLVLQSLDDPGLGLLVADPYSFLTDYQIRVGDPEQRLLKLENIRQVAVLVTVSIPAGQPEKTALNLTGPILINHRARIGLQVPQTDASLPPQFYLHMDDANGSTTVRRKASPPAAGEDKGDVQE
What is the function of this protein?
Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin.  Binds to flagellin and participates in the assembly of the flagellum.
What are the official names of this protein?
Flagellar assembly factor FliW.
What is the protein family that this protein belongs to?
Belongs to the FliW family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UCRI_MICAN
Sequence: MSQVSGTDVPDLGRRQFMNLLTFGTITGVAAGALYPIVKYFIPPSAGGTGGGVTAKDALGNDVIVSQFLTSHNAGDRTLAQGLKGDPTYLVVQEDKTLANYGINAVCTHLGCVVPWNASEEKFMCPCHGSQYNAEGKVVRGPAPLSLALAHANVTDNDKVVFSTWTETDFRTGEEPWWS
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex iron-sulfur subunit, Plastohydroquinone:plastocyanin oxidoreductase iron-sulfur protein, ISP, RISP, Rieske iron-sulfur protein.
What is the protein family that this protein belongs to?
Belongs to the Rieske iron-sulfur protein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein. Note=The transmembrane helix obliquely spans the membrane in one monomer, and its extrinsic C-terminal domain is part of the other monomer.
Protein: CU19_LOCMI
Sequence: GYLGGYAGYAAAPAAYAAAPAAYAAPAYAAPAVVKTAYAAPAIVKAAAPAVDYYSYPKYAFEYGVNDPHTGDVKRQWEERDGDVVRGEYSLLEPDGTTRTVTYTADAHNGFNAVVHRSGPSAHPAPAPAVAVPAVAKYVAAAPAVVKSVGYGGYGYH
What is the function of this protein?
Component of the cuticle of migratory locust which contains more than 100 different structural proteins.
What are the official names of this protein?
Cuticle protein 19, LM-ACP 19, LM-19.
Protein: ACPS_BACVZ
Sequence: MIFGIGIDIVELHRIENMLSRQARFPQRILTEAEYARFTLLSDKRKIEFLAGRFAAKEAFSKAYGTGIGKELSFQDIETGNDKAGKPVLACAKLDCATVHVSITHTKEYAAAQVVIERLSR
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.