PharMolix/UniProtQA huggingface dataset:
Protein: DBH_STAAR
Sequence: MNKTDLINAVAEQADLTKKEAGSAVDAVFESIQNSLAKGEKVQLIGFGNFEVRERAARKGRNPQTGKEIDIPASKVPAFKAGKALKDAVK
What is the function of this protein?
Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
What are the official names of this protein?
DNA-binding protein HU.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: 3CAR1_PICGL
Sequence: MSVISIMPLASKPCLNKSFISSTHEPKALRRPISTVGLCRRAKSVTASMSMSSSTAVSDDGVQRRIGNHHSNLWDDNFIQSLSSPYGPSSYGERAERLIGEVKEIFNRISMANGELVSHVDDLLQHLSMVDNVERLGIDRHFQTEIKVSLDYVYSYWSEKGIGPGRDIVCADLNTTALGFRVLRLHGYTVFPDVFEQFKDQMGRIACSANQTERQISSILNLFRASLIAFPWEKVMEEAEIFSTAYLKEALQTIPVSSLSREIQYVLDYRWHSDLPRLETRTYIDILRENATNETLDMKTEKLLELAKVEFNIFNSLQQNELKCVSRWWKESGSPDLTFIRHRQVEFYTLVSGIDMEPKRSTFRINFVKICHFVTILDDMYDTFGTIDELRLFTAAVTRWDKSATECLPEYMKGVYIDLYETVNELAREAHKSQGRDTLNYAREALEDYLGSYLKEAEWISTGYIPTFEEYLENGKVSSAHRIATLQPILMLDVPFPPHVLQEIDFPSKFNDLAGSILRLRGDTRCYQNDRARGEEASCISCYMKDNPGSTEEDALNHINGMIEKQIKELNWELLKPDKNVPISSKKHAFNISRGLHHFYKYRDGYTVANSETRNLVIKTVLEPVPM
What is the function of this protein?
Terpene synthase (TPS) involved in defensive oleoresin formation in conifers in response to insect attack or other injury.
What are the official names of this protein?
Carene synthase, chloroplastic, PgTPS-3car, (+)-car-3-ene synthase, 3-carene cyclase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsd subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MMSF_MAGSA
Sequence: MTEAILRSTLGARTTVMAALSYLSVLCFVPLLVDRDDEFVYFHAKQGLVIWMWGVLALFALHVPVLGKWIFGFSSMGVLVFSLLGLVSVVFQRAWKLPLISWVAHRI
What is the function of this protein?
Plays a major role in synthesis of cubooctahedral magnetite crystals by controlling crystal growth and morphology after nucleation (PubMed:22716969).  Has a partially redundant function with MamF (By similarity).  When overexpressed in E. coli the soluble protein self assembles into shells of about 36 nm.  This protein mediates the formation of magnetite nanoparticles from a solution of Fe(2+) and Fe(3+) sulfate; the crystals are larger and lack alternative iron oxide/oxyhydroxide species seen in the protein's absence (PubMed:25349410).
What are the official names of this protein?
Magnetosome protein MmsF.
What is the protein family that this protein belongs to?
Belongs to the magnetosome MamF/MmsF protein family.
What are the subcellular locations of this protein?
Magnetosome membrane; Multi-pass membrane protein. Note=Tagged protein forms straight lines with a punctate pattern extending along most of the cell associated with its inner curvature, in the correct position to be associated with magnetosomes (PubMed:22716969, PubMed:27481925, PubMed:26884433). During magnetosome formation protein is first dispersed in cell inner membrane, the gradually forms foci which align and form lines as the magnetic response increases (PubMed:26884433).
Protein: THAH_ARATH
Sequence: MSFVWSAAVWVIAVAAVVISKWLYRWSNPKCNGKLPPGSMGLPIIGETCDFFEPHGLYEISPFVKKRMLKYGPLFRTNIFGSNTVVLTEPDIIFEVFRQENKSFVFSYPEAFVKPFGKENVFLKHGNIHKHVKQISLQHLGSEALKKKMIGEIDRVTYEHLRSKANQGSFDAKEAVESVIMAHLTPKIISNLKPETQATLVDNIMALGSEWFQSPLKLTTLISIYKVFIARRYALQVIKDVFTRRKASREMCGDFLDTMVEEGEKEDVIFNEESAINLIFAILVVAKESTSSVTSLAIKFLAENHKALAELKREHAAILQNRNGKGAGVSWEEYRHQMTFTNMVINETLRMANMAPIMYRKAVNDVEIKGYTIPAGWIVAVIPPAVHFNDAIYENPLEFNPWRWEGKELRSGSKTFMVFGGGVRQCVGAEFARLQISIFIHHLVTTYDFSLAQESEFIRAPLPYFPKGLPIKISQSL
What is the function of this protein?
Hydroxylates thalianol into thalian-diol.
What are the official names of this protein?
Cytochrome P450 708A2, Thalianol hydroxylase, AtTHAH.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ACBP3_ARATH
Sequence: MEVFLEMLLTAVVALLFSFLLAKLVSVATVENDLSSDQPLKPEIGVGVTEDVRFGMKMDARVLESQRNFQVVDENVELVDRFLSEEADRVYEVDEAVTGNAKICGDREAESSAAASSENYVIAEEVILVRGQDEQSDSAEAESISSVSPENVVAEEIKSQGQEEVTELGRSGCVENEESGGDVLVAESEEVRVEKSSNMVEESDAEAENEEKTELTIEEDDDWEGIERSELEKAFAAAVNLLEESGKAEEIGAEAKMELFGLHKIATEGSCREAQPMAVMISARAKWNAWQKLGNMSQEEAMEQYLALVSKEIPGLTKAGHTVGKMSEMETSVGLPPNSGSLEDPTNLVTTGVDESSKNGIP
What is the function of this protein?
Binds medium- and long-chain acyl-CoA esters with very high affinity.  Can interact in vitro with arachidonyl-CoA, barely with oleoyl-CoA, but not with palmitoyl-CoA.
What are the official names of this protein?
Acyl-CoA-binding domain-containing protein 3, Acyl-CoA binding protein 3.
What is the protein family that this protein belongs to?
Belongs to the ACBP family.
Protein: FUCO2_HUMAN
Sequence: MRPQELPRLAFPLLLLLLLLLPPPPCPAHSATRFDPTWESLDARQLPAWFDQAKFGIFIHWGVFSVPSFGSEWFWWYWQKEKIPKYVEFMKDNYPPSFKYEDFGPLFTAKFFNANQWADIFQASGAKYIVLTSKHHEGFTLWGSEYSWNWNAIDEGPKRDIVKELEVAIRNRTDLRFGLYYSLFEWFHPLFLEDESSSFHKRQFPVSKTLPELYELVNNYQPEVLWSDGDGGAPDQYWNSTGFLAWLYNESPVRGTVVTNDRWGAGSICKHGGFYTCSDRYNPGHLLPHKWENCMTIDKLSWGYRREAGISDYLTIEELVKQLVETVSCGGNLLMNIGPTLDGTISVVFEERLRQMGSWLKVNGEAIYETHTWRSQNDTVTPDVWYTSKPKEKLVYAIFLKWPTSGQLFLGHPKAILGATEVKLLGHGQPLNWISLEQNGIMVELPQLTIHQMPCKWGWALALTNVI
What is the function of this protein?
Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
What are the official names of this protein?
Plasma alpha-L-fucosidase, Alpha-L-fucoside fucohydrolase 2, Alpha-L-fucosidase 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 29 family.
What are the subcellular locations of this protein?
Secreted.
Protein: IMPA6_ARATH
Sequence: MSYKPSAKTEVRRNRYKVSVDADEGRRRREDNMVEIRKNKREENLQKKRREGFNPSMASQPGQDFSSSLPTETRLENIQQMIAGVMSEDRDLQLEATASFRRLLSIERNPPINEVVQSGVVPHIVQFLSRDDFTQLQFEAAWALTNIASGTSENTRVIIDSGAVPLFVKLLSSASEEVREQAVWALGNVAGDSPKCRDHVLSCEAMMSLLAQFHEHSKLSMLRNATWTLSNFCRGKPQPAFEQTKAALPALERLLHSTDEEVLTDASWALSYLSDGTNEKIQTVIDAGVIPRLVQLLAHPSPSVLIPALRTIGNIVTGDDIQTQAVISSQALPGLLNLLKNTYKKSIKKEACWTISNITAGNTSQIQEVFQAGIIRPLINLLEIGEFEIKKEAVWAISNATSGGNHDQIKFLVSQGCIRPLCDLLPCPDPRVVTVTLEGLENILKVGEAEKNLGNTGNDNLYAQMIEDADGLDKIENLQSHDNNEIYEKAVKILESYWAADDEEEDIGGVDAPENVQSSGFQFGNQSGNAPTGGFNFG
What is the function of this protein?
Binds to conventional NLS motifs and mediates nuclear protein import across the nuclear envelope (By similarity).  Acts as cellular receptor for the nuclear import of the virD2 protein of Agrobacterium, but is not essential for Agrobacterium-mediated root transformation (PubMed:18836040).
What are the official names of this protein?
Importin subunit alpha-6, IMPa-6.
What is the protein family that this protein belongs to?
Belongs to the importin alpha family.
What are the subcellular locations of this protein?
Nucleus envelope.
Protein: CN10B_XENLA
Sequence: MAADKAGEQGAEKHEGSANCSGISDQEKELSRSALQAFTAGNYEACLQHLGELKEINKDDYKVILNAAVAEFYKSDKTTTDLLKQTLNQLRNEVHSAVDEMDSLDDVENSMLYYNQAVILYYLRQHMEAISVGEKLYQFIEPFEEKFAHAVCFLLVDLYLLTFQTEKALHLLVVLEKMILQGNSNNKNGKNNETNSNANNKELFAQKGDGGVNVEAAKSKIHQYKVRAYIQMKSLKACKREIKSVMNTSGNSAPSLFLKSNFEYLRGNYRKAVKLLNSSNIAEYPGFMKTGECVRCMFWNNLGCIHFAMGKHNLGLFYFKKALHENDNACAQLPSENSDPGKKFSGRPMCTLLTNKRYELLYNCGIQLLHIGRPLAAFEYLVEAVQVYHSNPRLWLRLAECCIAANKGTSEQETKGLPSKKGIVQSIVGQGYHRKIVLASQSVQNLLYNDGESSAIPVASMEFAAICLRNALLLLPEDQLETKQENGSKASSQTVNTDSSGESSDVCSNKNHEGDKFIPAPPSSPLRRQEVENLRCSVLACIAYVALALGDNLMALNHAEKLLQQPRLSGSLKFLGHLYAAEALISLDRISDAITHLNPENVTDVSLGVSSNEQEQGSDKGENEPMESAGKQIPQCYPSSVTSARTMMLFNLGSAYCLRSEYDKARKCLHQAASMIHPKEIPPEAILLAVYLELQNGNTQLALQIIKRNQLLPSIRMMSDLRKKPLFQTMHQPMQPIQMPAFAAAQRK
What is the function of this protein?
Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.  Additional complex functions may be a consequence of its influence on mRNA expression.  Is not required for association of CNOT7 to the CCR4-NOT complex (By similarity).
What are the official names of this protein?
CCR4-NOT transcription complex subunit 10-B.
What is the protein family that this protein belongs to?
Belongs to the CNOT10 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: LGT_ALIB4
Sequence: MEFWQNIYSHFNPVAFNLGSIAVHWYGIMYALALLSAIFVAKWFIKHDKLAISNDLFDSYIWWAEIGVILGARLGYVLFYDSHTMYYITHPWQIFNPYINGVYAGISGMSYHGAFFGFIIASYLFCRKNKVSFWFITDIAVLGVSAAYIFGRLGNFFNQELIGRVTDVPWGIYVGGVLRHPSQIYEAILEGLFVFLILAFYRKRKTFDGQLALMYGILYAIARIIAEFFRQPDSQLGFLVGEWLTMGILQSLIILIICVGFYVVRRKIIIKN
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUOI_LEGPC
Sequence: MKKVYHYIIHYVRTYLLLELLAGLWLTVKYFFRKKITVQFPEEQTPLSPRFRGLLALRRYPNGEERCIACKLCEAVCPALAITIESEQREDGSRRTTRYDIDMFKCINCGLCEESCPVDSIVVTPIHHYHISERGQNIMTKEKLLAVGDLMETQLAADRAADEKYR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LACD1_STRP3
Sequence: MTITANKRHYLEKVSHQGIISALAFDQRGALKQMMAAHQEGEATVTQIETLKVLVSEELTPYASSILLDPEYGLLATKVKANQTGLLLVYEKTGYDATTTSRLPDCLVEWSVKRLKAAGADAIKFLLYYDVDGDEQINLQKQAYIERIGSECTAEDIPFFLELLSYDERISDNNSAAYAKLKPHKVNGAMSVFSDKRFGVDVLKVEVPVNMAYVEGFTEGEVHYSQAEAIKAFQDQEAASHLPYIYLSAGVSAKLFQETLYFAAAAGAQFSGVLCGRATWAGSVPVYITKGEDEARKWLCTEGFQNIDELNRVLEETASPWTEKI
What are the official names of this protein?
Tagatose 1,6-diphosphate aldolase 1, D-tagatose-1,6-bisphosphate aldolase 1, Tagatose-bisphosphate aldolase 1.
What is the protein family that this protein belongs to?
Belongs to the aldolase LacD family.
Protein: Y2590_MYCBO
Sequence: MSQPPEHPGNPADPQGGNQGAGSYPPPGYGAPPPPPGYGPPPGTYLPPGYNAPPPPPGYGPPPGPPPPGYPTHLQSSGFSVGDAISWSWNRFTQNAVTLVVPVLAYAVALAAVIGATAGLVVALSDRATTAYTNTSGVSSESVDITMTPAAGIVMFLGYIALFALVLYMHAGILTGCLDIADGKPVTIATFFRPRNLGLVLVTGLLIVALTFIGGLLCVIPGLIFGFVAQFAVAFAVDRSTSPIDSVKASIETVGSNIGGSVLSWLAQLTAVLVGELLCFVGMLIGIPVAALIHVYTYRKLSGGQVVEAVRPAPPVGWPPGPQLA
What are the official names of this protein?
Uncharacterized protein Mb2590.
What is the protein family that this protein belongs to?
To M.tuberculosis Rv2560.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PAN2_NEOFI
Sequence: MEADWDELSRIPVPPPSPHGLPTAATTIAFDDVSELLWAGNEFGRITSFYGPELQRYTSVRAHPVSDGPVRQILFHERGVISLSPKSVHMITRRGLTQWHISHEEMTDLYCMSLTAQLNKIIVAGCQRAMFTIDIDKGIIVDKLHTDHNYTLMKKSRYLCAATDTGSVNALSLTDFRVVKSWKSHGTAINDMDARNDLLVTCGFSVRHLGSPIVDPLANVYDLKTLSPLPPIPFHAGAAYVRMHPKLSTTSFVASQTGQLQVVDLMNPNAINLRQANVSFMLGIDISPSGEALAINDAECSIHLWGSPSKIHFNEMSKEVEFADVVPRPPPLDWSPDTPLNMIGMPYYRERLLSAWPSHLVFEVGSPPAPIDQSLIPYLRPAEMGHYAPNPKKTRRYQVENTRALTTAEPALIAPKFLSEKAREQNKFKSEASVSDTAEALAGAKLNGEAEDDPLLKYSNVEIKYSRFGVDDFDFRFYNQTTFSGLETHIANSFTNALLQLLKFIPLVRNLALHHAASTCIYETCLLCEMGYLFDMLEKANGQNCQATNLLRTFSSYREASNLGLFEENLTTKSLSSAIQSVNRFFLNQIAHDFRMIVPSSDDLDQRLSTIASESIRCMFCQNEIVRPGNSLANELIYPAIDIKQARRNPAFRFSNILRASIERETQNRGWCNYCRRYQQVTIRKSIHRMPLVLILNAALSNPICRRLWSIPGWLPEEVGIAVDNGQVMCFEGDELKTQLQNKLPNLVVYELVGLVSEIDIPEHQKPHLVSFINVSISSRELEAKNRWHLFNDFLVTEVDKDEALRFNQPWKSPCILAYQAKDARHAVDDSWKNVLDITLLFRDWSLNGGRAVETRQTLTEEEKPTPGTPVALDTEFVDLEKAEIDVKADGSQEIVRPSKSGLARVSVLRGSGVHEGVPFIDDYITIKEPIVDYVTQYSGIKPGDLDPRTSQHNLVPLKVAYKKLWLLLNLGCVFVGHGLASDFRKINIQVPKSQTVDTQYLYFHPGKNRRLSLRYLAWAVFKEYIQEEPADNNQGHDSIEDARMALRLWKKFQEYEDAGIVNQILEEIFREGSKLGFRPPPRNGVATVLSRPGTAVTMQNSSGRNTPSTPDVGGAATATATTSAPATPRQAFRRSIALTPSNGTFGGPGAGDFFGGSPLK
What is the function of this protein?
Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover.  PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein pab1.  PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex.  Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by xrn1.  May also be involved in post-transcriptional maturation of mRNA poly(A) tails.
What are the official names of this protein?
PAN2-PAN3 deadenylation complex catalytic subunit pan2, PAB1P-dependent poly(A)-specific ribonuclease, Poly(A)-nuclease deadenylation complex subunit 2, PAN deadenylation complex subunit 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. PAN2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOP6A_HALS3
Sequence: MSETHTSDETEARDQLLAIAEQFYDQFADGDIPRMSLPTRSKSNIEYDEDADVWVYGDSQSTRSANSVRGARKLLKSVYTVDFLAQQLDEGRSSTLRELYYLSESWDEAEAQFNDQSESDKLVEDLEIVSGVKREDFHMRPEESGAKVMGPLRLREQTRRGDREIHCQEDVGQGGYQIPNNPDTIDFLDTDADFVLCVETGGMRDRLVENGFDDDYNAIVVHLGGQPARATRRLTKRLHDELDLPVTVFTDGDPWSYRIYGSVAYGSIKSAHLSEYLATPQAQFIGIRPQDIVDYDLPTDPLSDSDVNALESELEDPRFQSDFWTEQIGLQLDIDKKAEQQALASRGLDFVTDTYLPERLAEMGVL
What is the function of this protein?
Relaxes both positive and negative superturns and exhibits a strong decatenase activity.
What are the official names of this protein?
Type 2 DNA topoisomerase 6 subunit A, Type II DNA topoisomerase VI subunit A.
What is the protein family that this protein belongs to?
Belongs to the TOP6A family.
Protein: RK22_PELHO
Sequence: MIKKKNKKRYTEVSALGKYIPMSTHKARRVIDQIRGRSYEETLMILELMPYRACYPILKLISSAAANGIHNMNFDETSLIISKAEVNEGPTAKKFKPRAKGQSYPIKRSTCHITIVLRDISLNEKYEEYIRKPWALLEKSNETEIRKRN
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ACHA3_HUMAN
Sequence: MGSGPLSLPLALSPPRLLLLLLLSLLPVARASEAEHRLFERLFEDYNEIIRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGEWAIIKAPGYKHDIKYNCCEEIYPDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPTTHTMPSWVKTVFLNLLPRVMFMTRPTSNEGNAQKPRPLYGAELSNLNCFSRAESKGCKEGYPCQDGMCGYCHHRRIKISNFSANLTRSSSSESVDAVLSLSALSPEIKEAIQSVKYIAENMKAQNEAKEIQDDWKYVAMVIDRIFLWVFTLVCILGTAGLFLQPLMAREDA
What is the function of this protein?
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
What are the official names of this protein?
Neuronal acetylcholine receptor subunit alpha-3.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-3/CHRNA3 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: METH_RAT
Sequence: MKKTLQDEIEAILRKRIMVLDGGMGTMIQRYKLSEENFQGQEFKDHSRPLKGNNDILSITQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADYGLEHLAYRMNKCSADVARKAAEEITLQTGVKRFVAGSLGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLLDGGVDILLIETIFDTANAKAALFALQKLFEENYASPRPIFISGTIVDKSGRTLSGQTGEAFVTSVSHSDPLCIGLNCALGAAEMRPFIETIGKCTTAYVLCYPNAGLPNTFGDYDETPAMMAMHLKDFAVDGLVNVVGGCCGSTPDHIREIAEAVKNCKPRVPPDSVFEGHMLLSGLEPFRIGPYTNFVNIGERCNVAGSKKFAKLIMAGNYEEALSVAKVQVEMGAQVLDINMDDGMLDGPSAMTKFCNFIASEPDIAKVPLCIDSSNFAVIEAGLKCCQGKCIVNSISLKEGEEDFLEKARKIKKFGAAVVVMAFDEEGQATETDVKVSVCTRAYHLLVEKVGFNPNDIIFDPNILTIGTGMEEHNLYAINFIHATRVIKETLPGVRISGGLSNLSFAFRGMDAIREAMHGVFLYHAIKFGMDMGIVNAGSLPVYDDIHKDLLQLCEDLIWNRDAEATEKLLRYAQTHGKGGKKVIQTDEWRNGSIEERLEYALVKGIEKHIVEDTEEARLNREKYPRPLNIIEGPLMNGMKVVGDLFGAGKMFLPQVIKSARVMKKAVGHLIPFMEKEREEARVLNGSVEEEDPYQGTIVLATVKGDVHDIGKNIVGVVLGCNNFRVIDLGVMTPCDKILQAALDHKADIIGLSGLITPSLDEMIFVAKEMERLAIKIPLLIGGATTSRTHTAVKIAPRYSAPVIHVLDASKSVVVCSQLLDENLKDDYFEEILEEYEDIRQDHYESLKERKYLPLSQARKHSFHIDWLSEPHPVKPTFIGTQVFEDYNLQKLVDYIDWKPFFDVWQLRGKYPNRGFPKIFNDKAVGEEARKVYEDAQNMLSILISRKKLRARGVVGFWPAQSVQDDIHLYAEGAVPQAAEPIATFYGLRQQAEKDSSSTDPYHCLSDFVAPLHSGVRDYLGLFAVACFGVEELSKAYEDDGDDYSSIMVKALGDRLAEAFAEELHERVRRELWAYCGSEQLGVTDLRKLRYEGIRPAPGYPSQPDHTEKLTMWRLANIEQATGIRLTESLAMAPASAVSGLYFSNVKSKYFAVGKISKDQIEDYALRKNMSVAEVEKWLGPILGYDTD
What is the function of this protein?
Catalyzes the transfer of a methyl group from methylcob(III)alamin (MeCbl) to homocysteine, yielding enzyme-bound cob(I)alamin and methionine in the cytosol (PubMed:9219091, PubMed:9972236).  MeCbl is an active form of cobalamin (vitamin B12) used as a cofactor for methionine biosynthesis (PubMed:9219091, PubMed:9972236).  Cob(I)alamin form is regenerated to MeCbl by a transfer of a methyl group from 5-methyltetrahydrofolate (By similarity).  The processing of cobalamin in the cytosol occurs in a multiprotein complex composed of at least MMACHC, MMADHC, MTRR (methionine synthase reductase) and MTR which may contribute to shuttle safely and efficiently cobalamin towards MTR in order to produce methionine (By similarity).
What are the official names of this protein?
Methionine synthase, MS, 5-methyltetrahydrofolate--homocysteine methyltransferase, Cobalamin-dependent methionine synthase, Vitamin-B12 dependent methionine synthase.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 dependent methionine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPX_HAHCH
Sequence: MFRILLFLATNIAVVLVASVTLRLLGVEPYLQGSGLNLTSLLIFCAVFGMSGAMISLFLSKWIAKMSTRTQVIEQPRDAVESWLLDTVRELSSEAGIKMPEVGIFPAHQSNAFATGWNKNDALVAVSEGLLRRFSKDEIRAVLAHEIGHVANGDMVTLALIQGVINTFVMFFARIIGNIVDKAVFKNENGHGIGFFITTIFAEIVLGILASIIVMWFSRKREFRADAMGAKLAGSGAMIAALQRLKAETQMPNEMPDTLTAFGITEGVKQGFKALFSSHPPLDERIAALAANR
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SDHB_DICDI
Sequence: MISNVLKRASVLARSNGIQSAFYTTTAKTEASSSPQMKIKTAEKKDHFVNFQVYRYNEETTAKPYIQTYNINLKDCGPMVLDALLLIKNNIDPTLSFRRSCREGICGSCAMNLNGSNTLACTKKITDCLSGDTVKVYPLPHMHVVRDLIPDLSHFYTQHKSIKPWLEPAVDVPRYNGKEILQSKENRHKLDGLYECILCACCSTSCPSYWWSEGGDGGYLGPAVLLQAYRWIADSRDSIQKDRLAILSEDQMKVYKCHTIMNCTAVCPKGLNPGKSIANIKYLLAHN
What is the function of this protein?
Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
What are the official names of this protein?
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial, Iron-sulfur subunit of complex II, Ip.
What is the protein family that this protein belongs to?
Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: PROB_ALKOO
Sequence: MLQDVMKKSKKIVIKIGSNTLSNVDGTINHDFIEALCQQVAFLVGEGKQVVIVTSGARIAGISRTNKWSRKEDMNYKQALCAIGQVELMSAYNSHFSHHGIYIGQLLLTREDFFDKTRNLNIRNTLFTLVDEGIVPIINENDTVSVEQIKIGDNDTLAAYTATLWNADLLILLSDIDGIYNKNPKEYEDAELLEQVQNIDDMLKEIEVGETNSFGTGGIETKIEAARIVNRYNIPMILGNGKNKEILMKLYQNEAKATIFFRE
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_SHESH
Sequence: MSRVCQVTGKKPMVGNNRSHAKNSTRRRFLPNLQNHRFWLEGEKRFVKLRISTKGMRIIDKKGIEVVVAELRARGEKV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: TTCA_HAEIE
Sequence: MTQLAQQEKKQTYNFNKLQKRLRRNVGNAIADFGMIEDGDKVMVCLSGGKDSYTLLDILLNLQQSAPIKFDIVAVNLDQKQPGFPEHVLPEYLESIGVDYKIVQENTYGIVKEKIPEGKTTCSLCSRLRRGILYRTATELGATKIALGHHRDDMLATLFLNMFYGGKMKSMPPKLISDDGKQIVIRPLAYCKEKDIEKYAIAKKFPIIPCNLCGSQPNLQRQVVKEMLNTWDRQYPGRLETMFSAMQNITLSHMCDPKLFDFKGIKHGQLIDGIEGDTAFDEERITPMQFEDEDQTDFSNNEMINFKEVN
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPF_CORJK
Sequence: MNTPHIIPRVGIATDAHQVQPGKDCWMACLLWEDQDGCEGHSDGDVVAHAVVDALLSAAGLGDLGSFVGVGRQEYDNVSGERLLRECRELLESKGFVIGNAAVQMVGNRPKMGTRREEAEKVMGELIGAPVSVSATTTDHMGFTGRGEGVAAVATAVVWQAQN
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: YL015_MIMIV
Sequence: MSVSFPLSKNLHYRPEGNKLNITIGDLKVGSVEFVRETGCLKSECYYPLKWHEELNSWYRCCDNNCEEDHPVPEGVPFPTRINNNIQTLEWFEEKDTDLTQAITRIWNTYQLLQLN
What are the official names of this protein?
Uncharacterized protein L15.
What is the protein family that this protein belongs to?
Belongs to the mimivirus L15/L51/R83 family.
Protein: GPDA_ZYMMO
Sequence: MPVLEEKKTADHFHHIGVLGAGSWGTALAAVASYKGAVTLWGRKREIIDAINQRHINPDYLPDIIIPRTIHATDELNDLSSASALLVAIPAQKMRSVLRQIPNDSRPLILCAKGIEAESGLLMSQLAADIFPHRPIAVLSGPTFASEVARHLPTAVTLAAKEKDIRAALMQRLAIPTFRPYASSDVIGADVGGAVKNVLAIACGVVAGAKLGNNARAAVISRGFAEMNRFGIALGAKEETLTGLSGLGDLVLTCSSELSRNFTFGKKLGEGYSYEEQQKKRAVTTEGVFTAPVLQRVANKLKVEMPLVSAICDLIEGKSVNSVLERLLSRPLKGEYSISV
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.