PharMolix/UniProtQA huggingface dataset:
Protein: PGTB1_MOUSE
Sequence: MATTEDDRLAGSGEGERLDFLRDRHVRFFQRCLQVLPERYSSLETSRLTIAFFALSGLDMLDSLDVVNKDDIIEWIYSLQVLPTEDRSNLSRCGFRGSSYLGIPFNPSKNPGAAHPYDSGHIAMTYTGLSCLIILGDDLGRVDKEACLAGLRALQLEDGSFCAVPEGSENDMRFVYCASCICYMLNNWSGMDMKKAISYIRRSMSYDNGLAQGAGLESHGGSTFCGIASLCLMGKLEEVFSEKELNRIKRWCIMRQQNGYHGRPNKPVDTCYSFWVGATLKLLKIFQYTNFEKNRNYILSTQDRLVGGFAKWPDSHPDALHAYFGICGLSLMEESGICKVHPALNVSTRTSERLRDLHQSWKTKDSKQCSDNVHIAT
What is the function of this protein?
Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.  Known substrates include RAC1, RAC2, RAP1A and RAP1B (By similarity).
What are the official names of this protein?
Geranylgeranyl transferase type-1 subunit beta, Geranylgeranyl transferase type I subunit beta, GGTase-I-beta, Type I protein geranyl-geranyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the protein prenyltransferase subunit beta family.
Protein: MURG_CHLPM
Sequence: MNILFAGGGTGGHLYPAVAMAEEVQRMVPGASVLFAGTSRGIEAREVPRLGYRLHLLEVRGLRRGRSLKDMAANIGIAADFAAALASAVALVRRERPDVVVGTGGFVSAPVLFAAQLLGKKTLIQEQNAFPGVTTRLLSALATEVHLSFAEAARYLPKQKGVMVSGNPARSFTQVDASAAREHFGLDPSRPTLLVFGGSRGARSINNAVLRHHDLFCAAANLLWQTGSVDFERIRDACPPSRHLQIVPYIEEMGVAYSASDLVLCRAGASSIAELTNLAKPSVLVPYPYATGDHQRHNARALVHSGAAEVIEDSVLDSEESAAAIMELLHDGARRSAMSEAAGRLGAPDAARHLALRIISLAGTKQGS
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL3_GEOMG
Sequence: MKKGLIAKKLGMTQIFADDGRRIPVTVVEAGPCIVLQKKTVETDGYNAIQVGFLAKDADKSGRALVGHCKSAGQGVFTYIREFRVEDVDRYTIGDSITAEIFAPGDYVDVTGTSIGKGFQGVIKRWGFRGGRSSHGSCFHRAPGSIGSSAWPSRVFKNKKMPGQLGNERVTVQRLQVVRVDTADNLLLIRGAIPGAKNGILLLKDSVKAR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: UBD2B_XENLA
Sequence: MSVNMEELRHQVMINQFVLAAGCAADQAKQLLQAAHWQFETALSAFFQESNVASAQHHQHMMCTPSNTPATPPNFPDALAMFSKLRTSESLQNSSSPASNACSPPGNFNPYWASSPPNQQPVWLPPASPTAHLHHHHHHPQPVWPPNSQPTGGPQKAMAAMDGQR
What are the official names of this protein?
UBA-like domain-containing protein 2-B.
What is the protein family that this protein belongs to?
Belongs to the UBALD family.
Protein: MSH3_HUMAN
Sequence: MSRRKPASGGLAASSSAPARQAVLSRFFQSTGSLKSTSSSTGAADQVDPGAAAAAAAAAAAAPPAPPAPAFPPQLPPHIATEIDRRKKRPLENDGPVKKKVKKVQQKEGGSDLGMSGNSEPKKCLRTRNVSKSLEKLKEFCCDSALPQSRVQTESLQERFAVLPKCTDFDDISLLHAKNAVSSEDSKRQINQKDTTLFDLSQFGSSNTSHENLQKTASKSANKRSKSIYTPLELQYIEMKQQHKDAVLCVECGYKYRFFGEDAEIAARELNIYCHLDHNFMTASIPTHRLFVHVRRLVAKGYKVGVVKQTETAALKAIGDNRSSLFSRKLTALYTKSTLIGEDVNPLIKLDDAVNVDEIMTDTSTSYLLCISENKENVRDKKKGNIFIGIVGVQPATGEVVFDSFQDSASRSELETRMSSLQPVELLLPSALSEQTEALIHRATSVSVQDDRIRVERMDNIYFEYSHAFQAVTEFYAKDTVDIKGSQIISGIVNLEKPVICSLAAIIKYLKEFNLEKMLSKPENFKQLSSKMEFMTINGTTLRNLEILQNQTDMKTKGSLLWVLDHTKTSFGRRKLKKWVTQPLLKLREINARLDAVSEVLHSESSVFGQIENHLRKLPDIERGLCSIYHKKCSTQEFFLIVKTLYHLKSEFQAIIPAVNSHIQSDLLRTVILEIPELLSPVEHYLKILNEQAAKVGDKTELFKDLSDFPLIKKRKDEIQGVIDEIRMHLQEIRKILKNPSAQYVTVSGQEFMIEIKNSAVSCIPTDWVKVGSTKAVSRFHSPFIVENYRHLNQLREQLVLDCSAEWLDFLEKFSEHYHSLCKAVHHLATVDCIFSLAKVAKQGDYCRPTVQEERKIVIKNGRHPVIDVLLGEQDQYVPNNTDLSEDSERVMIITGPNMGGKSSYIKQVALITIMAQIGSYVPAEEATIGIVDGIFTRMGAADNIYKGQSTFMEELTDTAEIIRKATSQSLVILDELGRGTSTHDGIAIAYATLEYFIRDVKSLTLFVTHYPPVCELEKNYSHQVGNYHMGFLVSEDESKLDPGAAEQVPDFVTFLYQITRGIAARSYGLNVAKLADVPGEILKKAAHKSKELEGLINTKRKRLKYFAKLWTMHNAQDLQKWTEEFNMEETQTSLLH
What is the function of this protein?
Component of the post-replicative DNA mismatch repair system (MMR).  Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair.  When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs.  MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long.  After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.
What are the official names of this protein?
DNA mismatch repair protein Msh3, hMSH3, Divergent upstream protein, DUP, Mismatch repair protein 1, MRP1.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MSH3 subfamily.
Protein: H962L_ASFWA
Sequence: MGKPTLLEPGHLYNVPAEHKNDVPIHYIITWIKQRLPEFGGAIPTSLADRVLIIKSRTGSGKSTALPVHVFRILRNENTHSFQKYLGRSVICTQPRVLTAVTLAKDIGASTHYPDMILGQTVGYQTKPLTEKPNRGLIYATAGVLLAQLHTMTDDEIASRYAFMIIDEAHERALGIDLMLMYIKSMLERMLQRGSIGALRIPFVILTSATIDTHKYSTYFGIGKENIILVEGRQYGVETHWPLYNTNNYIKTACETALTIHKENIHDRPTEADILIFMPGMAEIRFLSMLLNNANMDLAKEKLPLMLILPIDSEAIAQENEAYLGLKAEIKNLWVKNPLTAKVEKPLRRVIVSTVVAETGLTIETLKYVIDPGWNRSIETYYPEWAGGLITRPAAQSRIEQRKGRVGRVFPGHFYPLYTKHVFEQIPAQQYPEIITEGPGAIFLSIVVETIKKNKEGVFKAEEIDMLDPPPTDALASAIERAIVAGLLTRGEKGLQLTQLGDIASRFSFLSIEEARMCFSGYFWQAAISDIATILAVVSVADKKLTNLLDSKQRNGAMLAEAVLAGIPPFLQNIDNAYTNIHLLLADDLLEGLFIFEGFQHAIVYFINNKVNNVAKHLREWCEKKMLKYSSMVQILARREDILNELAIVGLNPFHHWQNRLASANAETFLKRVCTLKQCMYEAYRLNCFCYDEHRLLYTGRNGIHFSYHDAVIKNPSCIVTPRIMLSPVSKQYMEWRLEPSFVSVLDGFVNVDINFLLPRQEIPNILGGVEDEEEEPPLPIQVFLHKYVKTHFHFSGKSFKELKMKPGQTIKFPETTLINMIPDIPKNVVQTYLEISVCHQYSFKRLIYCETFYTDMDDVQHENSVELIGLPMAAHHLTINDFNKLYHLLKPDGFLMVYDLHQSQEAFWLHSLQDALGHHTIRRDMDFHTIPEWETIFKECGFTPIFSKQPSEHELFIVFKK
What are the official names of this protein?
Putative RNA Helicase B962L.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein. Virion.
Protein: RL34_PSYA2
Sequence: MKRTFQPSVIKRKRTHGFRARMATKKGRQVLARRRAKGRHRLTV
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: PSBC_NICSY
Sequence: METLFNGTLALAGRDQETTGFAWWAGNARLINLSGKLLGAHVAHAGLIVFWAGAMNLFEVAHFVPEKPMYEQGLILLPHLATLGWGVGPGGEVIDTFPYFVSGVLHLISSAVLGFGGIYHALLGPETLEESFPFFGYVWKDRNKMTTILGIHLILLGLGAFLLVFKALYFGGVYDTWAPGGGDVRKITNLTLSPSIIFGYLLKSPFGGEGWIVSVDDLEDIIGGHVWLGSICILGGIWHILTKPFAWARRALVWSGEAYLSYSLGALSVFGFIACCFVWFNNTAYPSEFYGPTGPEASQAQAFTFLVRDQRLGANVGSAQGPTGLGKYLMRSPTGEVIFGGETMRFWDLRAPWLEPLRGPNGLDLSRLKKDIQPWQERRSAEYMTHAPLGSLNSVGGVATEINAVNYVSPRSWLATSHFVLGFFFFVGHLWHAGRARAAAAGFEKGIDRDFEPVLSMTPLN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP43 reaction center protein, PSII 43 kDa protein, Protein CP-43.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: SGCG_BOVIN
Sequence: MVREQYTTITEGTHIERPENQAVYKIGIYGWRKRCLYLFVLLLLIVLLVNFALTIWILRVMWFSPVGMGHLHVTADGLHLEGESEFLFPLYVKEIRSRVDSSLLLQSTQNVTMNARNTEGEVTGRLKVGPQMVEVQSQQFQIHSKDGKPLFTVDEEKVMVGTDKLRVTGPEGALFEHSVETPLVRPDPPQDLRLESPTRSLSMDAPKGIHIQAPAGKIEALTQMDIVLQSSDGTVVLDAETVCLPELALGSQGPAGSSQGLYEVCVCPDGKLYLSVAGMGTTCHEHSHLCL
What is the function of this protein?
Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
What are the official names of this protein?
Gamma-sarcoglycan, Gamma-SG.
What is the protein family that this protein belongs to?
Belongs to the sarcoglycan beta/delta/gamma/zeta family.
What are the subcellular locations of this protein?
Cell membrane, sarcolemma; Single- pass type II membrane protein. Cytoplasm, cytoskeleton.
Protein: MET16_YEAST
Sequence: MKTYHLNNDIIVTQEQLDHWNEQLIKLETPQEIIAWSIVTFPHLFQTTAFGLTGLVTIDMLSKLSEKYYMPELLFIDTLHHFPQTLTLKNEIEKKYYQPKNQTIHVYKPDGCESEADFASKYGDFLWEKDDDKYDYLAKVEPAHRAYKELHISAVFTGRRKSQGSARSQLSIIEIDELNGILKINPLINWTFEQVKQYIDANNVPYNELLDLGYRSIGDYHSTQPVKEGEDERAGRWKGKAKTECGIHEASRFAQFLKQDA
What is the function of this protein?
The NADP dependent reduction of PAPS into sulfite involves thioredoxin which probably plays the role of a thiol carrier.
What are the official names of this protein?
Phosphoadenosine phosphosulfate reductase, 3'-phosphoadenylylsulfate reductase, PAPS reductase, thioredoxin dependent, PAdoPS reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
Protein: CYB_HOMLA
Sequence: MPHHTLLLFNLLPVSLNISTWWNFGSMLLACLTLQITTGFFLALHYTANVNLAFSSIIHITRDVPYGWTMQNLHSIGASMFFICIYIHIARGLYYSSYLNKEVWLSGITLLATLMATAFFGYVLPWGQMSFWAATVITNLLTAIPYLGTSLTTWLWGGFSINDPTLTRFFALHFILPFAIVSLTSVHIVLLHNEGSSNPLGTNSDIDKIPFHPYHSYKDTLMLTFMITTLFMIMSFAPDLFNDPENFSKANPLITPQHIKPEWYFLFAYGILRSIPNKLGGTLALVMSIAILMTMPFTHTSLVRTMTFRPLSQLMFWTLIATFITITWTATKPVEPPFITIGQLTSILYFSFFMTNPLLGWTENKMMMTNT
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: HFQ_BRUA2
Sequence: MAERSQNLQDLFLNSVRKQKISLTIFLINGVKLTGIVTSFDNFCVLLRRDGHSQLVYKHAISTIMPSQPVQMFEGEEA
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs (By similarity).  Contributes to long-term survival under nutrient deprivation, to stationary phase-dependent hydrogen peroxide and acid stress resistance and is required for prolonged survival in the intracellular environment of the host macrophage.  Therefore, contributes not only to a generalized stress response in stationary phase but also to pathogenesis in mice, allowing the brucellae to adapt to the harsh conditions encountered within macrophages.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: FPG_BRUO2
Sequence: MPELPEVETVRRGLQPFMEGATVVRVEQNRPDLRFAFPENFAERLSGRRIEALGRRAKYLTVHLDDGLSIISHLGMSGSFRIEAEDAQGLPGGFHHERSKNSLHDHVVFHLMRSDGASARIIYNDPRRFGFMLFAEKGALEEHPLLKDLGVEPTGNLLSGEVLAALFKGRRTPLKAALLDQRLIAGLGNIYVCEALWRAGLSPMRAAGSVAGEMDVMERLAGAIRSVIAQAIAAGGSSLKDYIQADGALGYFQHSFSVYGREGKPCRNPACGGTVERVVQSGRSTFFCASCQT
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: TUSE_ECOLI
Sequence: MLIFEGKEIETDTEGYLKESSQWSEPLAVVIAENEGISLSPEHWEVVRFVRDFYLEFNTSPAIRMLVKAMANKFGEEKGNSRYLYRLFPKGPAKQATKIAGLPKPVKCI
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.  Could accept sulfur from TusD.
What are the official names of this protein?
Sulfurtransferase TusE, tRNA 2-thiouridine synthesizing protein E.
What is the protein family that this protein belongs to?
Belongs to the DsrC/TusE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_SHISS
Sequence: MQVSVETTQGLGRRVTITIAADSIETAVKSELVNVAKKVRIDGFRKGKVPMNIVAQRYGASVRQDVLGDLMSRNFIDAIIKEKINPAGAPTYVPGEYKLGEDFTYSVEFEVYPEVELQGLEAIEVEKPIVEVTDADVDGMLDTLRKQQATWKEKDGAVEAEDRVTIDFTGSVDGEEFEGGKASDFVLAMGQGRMIPGFEDGIKGHKAGEEFTIDVTFPEEYHAENLKGKAAKFAINLKKVEERELPELTAEFIKRFGVEDGSVEGLRAEVRKNMERELKSAIRNRVKSQAIEGLVKANDIDVPAALIDSEIDVLRRQAAQRFGGNEKQALELPRELFEEQAKRRVVVGLLLGEVIRTNELKADEERVKGLIEEMASAYEDPKEVIEFYSKNKELMDNMRNVALEEQAVEAVLAKAKVTEKETTFNELMNQQA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
Protein: MATP_ECO45
Sequence: MKYQQLENLESGWKWKYLVKKHREGELITRYIEASAAQEAVDELLSLENEPVLVNGWIDKHMNPELVNRMKQTIRARRKRHFNAEHQHTRKKSIDLEFIVWQRLAGLAQRRGKTLSETIVQLIEDAENKEKYANKMSSLKQDLQALLGKE
What is the function of this protein?
Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle.  Prevents early segregation of duplicated Ter macrodomains during cell division.  Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.
What are the official names of this protein?
Macrodomain Ter protein.
What is the protein family that this protein belongs to?
Belongs to the MatP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TCTP_BRABE
Sequence: MIIYKDIVSGDEMFSDAYKMKVLDDYFYELEGKITTEKGGIDESAIGGNASAEDAVEGLEESGTTGCNIVIAQRLQETQFTKAQYKVYIKDYSKKVLEYLTKNKPERVDGFKAASAAGMKRVMGNFKNWQFFTGEKMDQDGMVALMDYREDGKTPYMLFFKDGLEEEKF
What is the function of this protein?
Involved in calcium binding and microtubule stabilization.
What are the official names of this protein?
Translationally-controlled tumor protein homolog, TCTP.
What is the protein family that this protein belongs to?
Belongs to the TCTP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDI23_ARATH
Sequence: MYKSPLTLLTLLTICFGFFDLSSALYGSSSPVVQLTASNFKSKVLNSNGVVLVEFFAPWCGHCKALTPTWEKVANILKGVATVAAIDADAHQSAAQDYGIKGFPTIKVFVPGKAPIDYQGARDAKSIANFAYKQIKGLLSDRLEGKSKPTGGGSKEKKSEPSASVELNASNFDDLVIESNELWIVEFFAPWCGHCKKLAPEWKRAAKNLQGKVKLGHVNCDVEQSIMSRFKVQGFPTILVFGPDKSSPYPYEGARSASAIESFASELVESSAGPVEVTELTGPDVMEKKCGSAAICFISFLPDILDSKAEGRNKYLEMLLSVAEKFKKQPYSFMWVAAVTQMDLEKRVNVGGYGYPAMVAMNVKKGVYAPLKSAFELQHLLEFVKDAGTGGKGNVPMNGTPEIVKTKEWDGKDGELIEEDEFSLDELMGGDDAVGSKDEL
What is the function of this protein?
Acts as a protein-folding catalyst that interacts with nascent polypeptides to catalyze the formation, isomerization, and reduction or oxidation of disulfide bonds.
What are the official names of this protein?
Protein disulfide-isomerase 2-3, AtPDIL2-3, Protein disulfide-isomerase 5-2, AtPDIL5-2, Protein disulfide-isomerase 9, PDI9.
What is the protein family that this protein belongs to?
Belongs to the protein disulfide isomerase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: TPIS_ECOLI
Sequence: MRHPLVMGNWKLNGSRHMVHELVSNLRKELAGVAGCAVAIAPPEMYIDMAKREAEGSHIMLGAQNVDLNLSGAFTGETSAAMLKDIGAQYIIIGHSERRTYHKESDELIAKKFAVLKEQGLTPVLCIGETEAENEAGKTEEVCARQIDAVLKTQGAAAFEGAVIAYEPVWAIGTGKSATPAQAQAVHKFIRDHIAKVDANIAEQVIIQYGGSVNASNAAELFAQPDIDGALVGGASLKADAFAVIVKAAEAAKQA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TATA_MYCGI
Sequence: MGGLQPWHWLIVIAVFVLLFGAKKLPDAARSLGKSMRIFKSEIKEMQSDSNAAKSDQPEQITSERVVVDPSTQSTSSNSDKRPA
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: SWS_DROGR
Sequence: MDVLELLRASATGCYNTIFSEAWHQYVHKQIAAAVYWYGALFLLGVLLFVWFLYFKRLARLRLRDEIARSLSAVTSAATGVDHRGLRFRKRDKMLFYGRRMLRKMKNVSGQMYSSGKGYKRRAVMRFARRILQLQRENRPLEMKTVEPPAEYLEETIEGSDRVPPDALYMLQSIRIFGHFEKPIFLKLCKHTQILQLMAGDYLFKITDPDDSVYIVQSGMINVYICNADGSTLSLKTVRKGESVTSLLSFIDVLSGNSSYYKTVTAKAIEKSVVIRLPMQAFEEVFDENPDVMIRVIQVIMIRLQRVLFTALRNYLGLNAELVQNHMRNKNSSNPMATGQTTSNVQSQTSQATQSRPSGTTRTPTSPMLRLSREEHTLSDPDPNPNANNLHYHEMHGDAPYIDLYHYQQQQQSLNSPRRNSTAHVSEAAAASTASSPTTIDQRLVQSSAVDSLRRELGLGEEDAHIIEQFVLVRELEPNVTLITEGNADDVCIWFVMTGNLAVYQSNADATRASAKQDAKPEMLIHFVHPGEIVGGLAMLTGEASAYTIRSRNNSRVAFIRRAAIYQIMRQRPRIVLGLGNGVVRRLSPLVRQCDYALDWIFLESGRAVYRQDESSDSTYIVLSGRMRSVITQPNGKKEIVGEYGKGDLVGIVEMITETSRTTTVMAVRDSELAKLPEGLFNAIKLRYPIVVTRLISFLSHRFLGSMQTRGSNAYGTPVEANPVTHKYSTVALVPITDDVPLTPFTYELYHSLCAIGPVLRLTSEVVGKQLGVNIFDTANEYRLTSWLAQQEDRNIITLYQCDSSLSPWTQRCMRQADVILIVGLGERSHLVGKFEREIDKLAMRTQKELVLLYPETTNAKPANTLSWLNARPWVTKHHHVLCVKRIFTRKSQYRINDLYSRVLLSEPNMHSDFSRLARWLTGNSIGLVLGGGGARGAAHIGMLKAIQEAGIPIDMVGGVSIGALMGALWCSERNITTVTQKAREWSKKMTKWFLQLLDLTYPITSMFSGREFNKTIHDTFGDVTIEDLWIPYFTLTTDITASCHRIHTNGSLWRFVRSSMSLSGYMPPLCDPQDGHLLLDGGYVNNLPGHLWRYCRASMSIAGVFPPFCDYRDGHLLLDGCYTNNVPADVMHNLGAAHIIAIDVGSQDDTDLTNYGDDLSGWWLLYKKWNPFTSPVKVPDLPDIQSRLAYVSCVRQLEEVKNSDYCEYIRPPIDKYKTLAFGSFDEIRDVGYVFGKNYFDTMAKAGRLGRFNQWFNKEPPKRGNHASLNEYTFIDLAQIVCKLPETYVRLGTPDLFSEDEDEDFDGYISEPTTLNTDRRRIQVHRAGNSLSFSEAELDSDVELDLEMENKVDKATQSTPTLPDKRSVQTPTPSLFNLTMPIAVDEIDKSSGRVKRKLEATNTASIAEPEASPSIKAEATTQTTPPTSKRTEQDEHELEHEQVVEKQQVMDKQQGNTTNNDTKN
What is the function of this protein?
Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho).  This deacylation occurs at both sn-2 and sn-1 positions of PtdCho.  Its specific chemical modification by certain organophosphorus (OP) compounds leads to distal axonopathy.  Plays a role in the signaling mechanism between neurons and glia that regulates glia wrapping during development of the adult brain.  Essential for membrane lipid homeostasis and cell survival in both neurons and glia of the adult brain (By similarity).
What are the official names of this protein?
Neuropathy target esterase sws, Swiss cheese.
What is the protein family that this protein belongs to?
Belongs to the NTE family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=Sws tethers Pka-C3 to the membrane.
Protein: Y963_STAAB
Sequence: MEYEYPIDLDWSNEEMISVINFFNHVEKYYESGVTAGDFMGAYKRFKEIVPAKAEEKQIFNTFEKSSGYNSYKAVQDVKTHSEEQRVKAKK
What are the official names of this protein?
UPF0223 protein SAB0963.
What is the protein family that this protein belongs to?
Belongs to the UPF0223 family.
Protein: PTPA1_CRYNB
Sequence: MQPHTQPPQPEASSSRAVHIPSDPAPPRPCLTNDAIVSRWQSSPGFQYFWAWIKRRCDRLKGKEIIRGPFDHSAHGIRSLMNMLDQMTSWVEDATPQPQSNQRFGNLAFRTYNKLLQERLPPLIDSWDIPSNLRSQLLPLFINSHAFGHPTRLDYGTGHELAFVLGLWCCVVPGWVGGDNGTEEEEDELILRVFTRYLELTTFLQKTYNLEPAGSHGVWGLDDYCFLPYLFGSAQLLGSNLTPSASLSLALSHHPSATSPPSAPITDLYTLSLHHLTLFKFGASFSEHSPLLYSLSQMPNWVKPHGGLKKMFLGEVVGKRVVVQGIWVGGWCWGEDVPNVEERGDKNEGKGTDAGTKAPWAR
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.  Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase.  Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A activator 1, Peptidyl-prolyl cis-trans isomerase PTPA-1, PPIase PTPA-1, Rotamase PTPA-1, Phosphotyrosyl phosphatase activator 1.
What is the protein family that this protein belongs to?
Belongs to the PTPA-type PPIase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: UNG_ALIFM
Sequence: MALTWNSIISAEKNKAYYQSMSEKIDAQRSLGKSIFPKEDHIFTAFDLTPFNDVKVVILGQDPYHGEGQAHGLSFSVLPGVKIPPSLRNMYKELAEDIPGFTIPEHGYLKTWAEQGVLLLNTVLTVEEAKAHSHAKFGWETFTDAIIKKINDDMEGVIFLLWGAHAQKKGANIDTSRHFILQAPHPSPLSAHRGFFGCKHFSQTNELLRQQNLSEINWGSVTSS
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGC_HALH5
Sequence: MKVGIVGATGYGGLELIRLLSQHPNVEEIICYSSSQEGLPLDDMYPHLSGNVRWTLKAIDPEAIRADVDTVFLATPPGVSGELTPDLVKLGLKVIDLSGDLRINEPDVYEAWYKRQAAPVGTIRGAVYGLTEWQRDEIAAAQIIANPGCYPTAVLLGLAPLVQQKWIDPKRIIIDAKSGTSGAGRNPSQITHFSEMNENFKIYQVNQHKHTPEIEQQLRNWDESVGNVTFSTHLVPMVRGIMATIYAEANQAISEKELREHFAYVYETSPFVHVYSEGRYPATKEVFGSNRCHIGVTYDERTNRITVVSVIDNLVKGAAGQAIQNYNVMNGYEETLGLEGSPLYP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.