PharMolix/UniProtQA huggingface dataset:
Protein: PELO_PONAB
Sequence: MKLVRKNIEKDNAGQVTLVPEEPEDMWHTYNLVQVGDSLRASTIRKVQTESSTGSVGSNRVRTTLTLCVEAIDFDSQACQLRVKGTNIQENEYVKMGAYHTIELEPNRQFTLAKKQWDSVVLERIEQACDPAWSADVAAVVMQEGLAHICLVTPSMTLTRAKVEVNIPRKRKGNCSQHDRALERFYEQVVQAIQRHIHFDVVKCILVASPGFVREQFCDYMFQQAVKTDNKLLLENRSKFLQVHASSGHKYSLKEVLCDPTVASRLSDTKAAGEVKALDDFYKMLQHGPDRAFYGLKQVEKANEAMAIDTLLISDELFRHQDVATRSRYVRLVDSVKENAGTVRIFSSLHVSGEQLSQLTGVAAILRFPVPELSDQEDDSSSEED
What is the function of this protein?
Cotranslational quality control factor involved in the No-Go Decay (NGD) pathway.  In the presence of ABCE1 and HBS1L, is required for 48S complex formation from 80S ribosomes and dissociation of vacant 80S ribosomes.  Together with HBS1L and in presence of ABCE1, recognizes stalled ribosomes and promotes dissociation of elongation complexes assembled on non-stop mRNAs; this triggers endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and to degrade damaged mRNAs as part of the No-Go Decay (NGD) pathway.  As part of the PINK1-regulated signaling, upon mitochondrial damage is recruited to the ribosome/mRNA-ribonucleoprotein complex associated to mitochondrial outer membrane thereby enabling the recruitment of autophagy receptors and induction of mitophagy.
What are the official names of this protein?
Protein pelota homolog.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: 3SIMA_DENPO
Sequence: LTCVTSKSIFGITTENCPDGQNLCFKKWYYLNHRYSDITWGCAATCPKPTNVRETIHCCETDKCNE
What is the function of this protein?
Selectively binds with high-affinity to the a2B-adrenoceptor subtype (ADRA2B) (PubMed:20466015).  The toxin reversibly binds to ADRA2B, and its mode of inhibition is non-competitive (PubMed:20466015).  The toxin has also been described to bind with high affinity to all muscarinic receptor subtypes (Ki=23 nM (on CHRM1), Ki=44 nM (on CHRM2), Ki=3 nM (on CHRM3), Ki=5 nM (on CHRM4), and Ki=8 nM (on CHRM5)) but no other data support these affinity values (PubMed:8536706).
What are the official names of this protein?
Muscarinic toxin alpha, MT-alpha.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Aminergic toxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CDH_MYCTA
Sequence: MPKSRRAVSLSVLIGAVIAALAGALIAVTVPARPNRPEADREALWKIVHDRCEFGYRRTGAYAPCTFVDEQSGTALYKADFDPYQFLLIPLARITGIEDPALRESAGRNYLYDAWAARFLVTARLNNSLPESDVVLTINPKNARTQDQLHIHISCSSPTTSAALRNVDTSEYVGWKQLPIDLGGRRFQGLAVDTKAFESRNLFRDIYLKVTADGKKMENASIAVANVAQDQFLLLLAEGTEDQPVAAETLQDHDCSITKS
What are the official names of this protein?
CDP-diacylglycerol pyrophosphatase, CDP-diacylglycerol phosphatidylhydrolase, CDP-diglyceride hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Cdh family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: Y2430_RHIE6
Sequence: MSKPPSDPPRRPPAAFAYEDEASEPRNSGRQQQGRRKPESFSENIVVTPDEDDPFINPDSDLIAPPVATPRKRRTSFGKIAAGAFGILLSLGLGLWTDRLIRDLFTRADWLGYAALGVLAIGILAVLALVIRETAGMMRLAAVQTIKAEAEAAILETRPAKARAVLARLTTLLAANPETSKGRATLKATEGEVIDPPHLMALAERELLAPLDRKARALIVNASKRVSIVTAVSPRAVVDLLYVLYEAVRLIRAMAELYGGRPGTLGMFRLLRDVLAHLAVTGSIAVGDSLVQQVLGHGLASKLSARLGEGVINGLMTARIGIAAMDLCRPLAFRTLKRPGIGDFIADLTPSMSPRGNNP
What are the official names of this protein?
UPF0283 membrane protein RHECIAT_CH0002430.
What is the protein family that this protein belongs to?
Belongs to the UPF0283 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RSXA_SALTY
Sequence: MTDYLLLFVGTVLVNNFVLVKFLGLCPFMGVSKKLETAMGMGLATTFVMTLASICAWLIDTWILIPLDLIYLRTLAFILVIAVVVQFTEMVVRKTSPALYRLLGIFLPLITTNCAVLGVALLNINLGHHFLQSALYGFSAAVGFSLVMVLFAAIRERLAVADVPAPFRGNAIALITAGLMSLAFMGFSGLVKL
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit A, Rsx electron transport complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EFG1P_CRYNJ
Sequence: MPADKKQRKGAHPYRKPRPNPSDPSSSDKPARPKPTHRIPATEARDGAGIPGLSKLKSSIRQTKRLLAKENLEPGLRVSTQRRLTSLEADLAAAERREVERKNGAKYHKVKFFERQKLVRLIKRFKRKLLDSETSSKKRSKHEEELLDARIMLNYVLHYPNTQKYISLFPSNPNQTEDEDDDDDSSKPKLKLPPLLHPVPSTEECEKMDKPTKRRYDLLLETKRLMEESKLKSEPETDLKKGQVDGVVVGLGADVQIGLGDKKEAKQNAAQGTGEEEDDFFESGDE
What is the function of this protein?
Involved in rRNA processing.
What are the official names of this protein?
rRNA-processing protein EFG1.
What is the protein family that this protein belongs to?
Belongs to the EFG1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ACP_SALPA
Sequence: MSTIEERVKKIIGEQLGVKQEEVTNNASFVEDLGADSLDTVELVMALEEEFDTEIPDEEAEKITTVQAAIDYINGHQA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BSC11_ALTBR
Sequence: MIFLAPFEFLDPLRHALPLTCTGLIIIFAFYLSRHHSPKPAPNIPIHSYDREEYFRRGYELVQEGQKKHPSCFQLRTATGWKILVPIRFVEELRKNPSLSFARGNDKDAFIEYPGFEAMEAACHDDYFMQEVVRVKLTQTLNLLYSSVIDESAVAMSEVLGEDKIWRTLRIKDDINHIVARVTSRVFLGFPLCRNQKWLDIVVNHTKAVFMAQKRMRQTPPALRPLIHYFLPETKLLRQHLHAARTLISPELAKRRAAVEEALRHGKIPKESANAISWMVEVSQAQGRKIDVAVHVVSLSMTAIQTTSEVMTNCILQLCETPSIVDDLRAEIIFLLKEGGWTKYTLYKMRLLDSFIREVMRHHDFLRVTSWRGCTEDVVLSDGTVLPKGSCIYFDDSKVVDPEHYPDPEKFDPMRSFKKREQPGQEDRHQFVSLQTDHMAFGYGIHACPGRFFANMELKVMLCNFLLKYDVRLVPGEKRPVDILFEVQRMVPPDVRVQIKVRDQEPEVDLYSPISST
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of the diterpene glucoside brassicicene C (PubMed:19097780).  In the first step of the brassicicene C biosynthesis, the bifunctionnal diterpene synthase bsc8 that possesses both prenyl transferase and terpene cyclase activity, converts isopentenyl diphosphate and dimethylallyl diphosphate into geranylgeranyl diphosphate (GGDP) that is further converted into fusicocca-2,10(14)-diene, the first precursor for brassicicene C (PubMed:19097780).  Fusicocca-2,10(14)-diene is then substrate of cytochrome P450 monooxygenase bsc1 for hydroxylation at the C-8 position (PubMed:19700326).  Oxidation at C-16 position to aldehyde is then catalyzed by the cytochrome P450 monooyxygenase bsc7, yielding fusicocca-2,10(14)-diene-8-beta,16-diol (PubMed:19700326).  Follows the isomerization of the double bond and reduction of aldehyde to alcohol catalyzed by the short-chain dehydrogenase/reductase bsc3 to yield the diol compound fusicocca-1,10(14)-diene-8 beta,16-diol (Probable).  The next step is the oxidation at the C-3 position of fusicocca-2,10(14)-diene-8-beta,16-diol catalyzed by the alpha-ketoglutarate dependent dioxygenase bsc9, to produce a triol compound (PubMed:21299202).  Methylation of the hydroxy group at position 16 is performed by the methyltransferase bsc6 (PubMed:19097780).  16-O-methylation is followed by oxidation at the C-13 position to ketone and an alkyl shift of the methyl group leads to brassicicene C (Probable).  Although the probable acetyltransferase bsc4 is included in the gene cluster, no acetylation reactions are necessary for brassicicene C biosynthesis.  However, the fact that brassicicene E, which is a structurally related compound having an acetoxy group at position 12, was previously isolated from another strain of A. brassicicola suggests that the ATCC 96836 strain might also produce a small amount of brassicicene E (Probable).
What are the official names of this protein?
Cytochrome P450 monooxygenase bsc11, Brassicicene C biosynthetic gene cluster protein 11, Cytochrome P450 monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: URE3_ACIB3
Sequence: MELNPTEKDKLLIFTAGLVAERRKARGLKLNYPEAVAFISAALLEGARDGMTVSELMHFGTTLLKREDVMDGVPEMIAEVQVEATFPDGSKLVTVHQPIV
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YACG_BRUME
Sequence: MTPLRPTRPCPECGKPSTREAYPFCSPRCKNIDLNRWLSGSYVIAGKPLGEEDENDS
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: RUVA_STRSV
Sequence: MYEYFKGIISKITAKYIVLEVNSIGYILHVANPYAYSGQLHQEAKVYVHQVVREDAELLYGFATEEEKQLFLSLISVSGIGPVSALAIIAADDNAGLVQAIEQKNITYLTKFPKIGKKTAQQMVLDLEGKVVAAGSPAESKAPVQTADNQELEEAMEAMLALGYKAAELKKIKKFFEGTTDTAENYIKSALKMLVK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: NXNL1_DANRE
Sequence: MVDLFLGKVLVKNNKDRDELDTEREIILRLQNRILMLFFGSGDSEKCQDFAPTLKDFYKKLTDEFYVERSAQLVLLYISLDSSEEQQEKFLKELPKRCLFLPYEDPYRQELGVMFEVRDLPRVVVLRPDCSVLSPNAVSEICTLGTDCFRNWQEGAELIDRNFMMNEEFDEGKMRSMTDPIRRIKYKVEDEKKKKKKRDDDDDDDDGGGGGGPWG
What is the function of this protein?
Plays an important role in retinal cone photoreceptor survival (By similarity).  May play a role in cone cell viability, slowing down cone degeneration, does not seem to play a role in degenerating rods (By similarity).
What are the official names of this protein?
Nucleoredoxin-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the nucleoredoxin family.
What are the subcellular locations of this protein?
Cell projection, cilium, photoreceptor outer segment.
Protein: PSBC_PHYPA
Sequence: MKILYSQRRFYHVETLFNGTLALSGRDQETTGFAWWAGNARLINLSGKLLGAHVAHAGLIVFWAGAMNLFEVAHFVPEKPMYEQGLILLPHLATLGWGVGPGGEVIDTFPYFVSGVLHLISSAVLGFGGIYHALIGPETLEESFPFFGYVWKDKNKMTTILGIHLILLGAGAFLLVFKALYFGGIYDTWAPGGGDVRKITNLTLSPGVIFGYLLKSPFGGEGWIVSVDNLEDIIGGHVWLGSICIFGGIWHILTKPFAWARRALVWSGEAYLSYSLGAIAVFGFIACCFVWFNNTAYPSEFYGPTGPEASQAQAFTFLVRDQRLGANVGSAQGPTGLGKYLMRSPTGEIIFGGETMRFWDLRAPWLEPLRGPNGLDLSKLKKDIQPWQERRSAEYMTHAPLGSLNSVGGVATEINAVNYVSPRSWLATSHFVLGFFFFVGHLWHAGRARAAAAGFEKGIDRDFEPVLSMTPLN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP43 reaction center protein, PSII 43 kDa protein, Protein CP-43.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: TRPB_STRP4
Sequence: MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSFQEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLAKRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKVEAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQQYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGLGVDTEHHAATLTKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTDEEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVKDRLEADAAKKGEAHA
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: TTCA_IDILO
Sequence: MASENKYSFNKLQKRIRRDAGKAIQDFGMIEDGDHIMVCLSGGKDSYTLLDTLLYLQKVAPVRFSLVAVNLDQKQPGFPEHVLPAYLNKLGVDYKIVEEDTYSIVKEKIPEGKTTCSLCSRLRRGILYRTAKELKATKIALGHHRDDMIETLFLNMFHGGKLKSMPPKLASDNGEHVVIRPLAYAREKDIEQYSAAMEFPIIPCNLCGSQENLQRKQIKQMLNGWDKQFPGRIESLFTAMQNVVPSHLADSALFDFKAVTADGVADENGDKAFDTDSFTTNFETEDSPVFASNIPIKHLA
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YNQ5_YEAST
Sequence: MDRVRSLIGNRRGRRHNRQHPPYPHSGSPSTVNLLGANGYGDDQSTIFARENESLETSANEGDDSADAATLNTAVSEGSTIGDLQRQGYVNRAPRFTSERAMPFVSVLLQRGFFAFPSEESLQLFLHNKRKLDNIDPKRGLGLPLFHAISLNLVKSLFSDQNTPVMRIYKYVMIDSQCDKPPLNSEVVSRINENVSIYKYEFCTILKKMESHNFSSRVEHDFIFHRKDEPDVHIPMINYNQRKNADTAIHGLNLRWYGTTSLASPFGSNSINLLVLDDTMASYMNQQTIEEFDSYSRSRPTRPLGYLPVWARYTDDKVSVIPKKRTLRVATLYLQETDSFDDGSSLTSTNYTEMGSNIIENVPWDSQILTCMCMLLHEYESRKEKRHTAWGSSTTYMLNGPAGLLM
What are the official names of this protein?
Uncharacterized protein YNL165W.
What is the protein family that this protein belongs to?
To yeast YMR316w.
Protein: DCUP_SYNSC
Sequence: MSDSLPLLLRAARGESVERPPVWMMRQAGRYMKIYRDLRDKYPSFRERSENPDLSYEISMQPFHAFKPDGVILFSDILTPLPGMGIDFDIIESKGPQIGDPIRSMAQVDALRPLNPSESMPFVGEVLGRLRQSVGNEAAVLGFVGAPWTLAAYVVEGKSSKNYAVIKAMVFREPEILHKLLDHFAESIANYLRYQIDSGAQVVQMFDSWAGQLSPADYDTFAAPYQKKVVDLVKKTHPDTPFILYISGSAGVIERMANTGVDIVSLDWTVDMAEALARLPEHIGVQGNVDPGLLFGTPEAIEARIDDCVRKARGRKHILNLGHGILPGTPEENGEAFFRAGKSVMDRLGAVV
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARX_HUMAN
Sequence: MSNQYQEEGCSERPECKSKSPTLLSSYCIDSILGRRSPCKMRLLGAAQSLPAPLTSRADPEKAVQGSPKSSSAPFEAELHLPPKLRRLYGPGGGRLLQGAAAAAAAAAAAAAAAATATAGPRGEAPPPPPPTARPGERPDGAGAAAAAAAAAAAAWDTLKISQAPQVSISRSKSYRENGAPFVPPPPALDELGGPGGVTHPEERLGVAGGPGSAPAAGGGTGTEDDEEELLEDEEDEDEEEELLEDDEEELLEDDARALLKEPRRCPVAATGAVAAAAAAAVATEGGELSPKEELLLHPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKAGAQTHPPGLPFPGPLSATHPLSPYLDASPFPPHHPALDSAWTAAAAAAAAAFPSLPPPPGSASLPPSGAPLGLSTFLGAAVFRHPAFISPAFGRLFSTMAPLTSASTAAALLRQPTPAVEGAVASGALADPATAAADRRASSIAALRLKAKEHAAQLTQLNILPGTSTGKEVC
What is the function of this protein?
Transcription factor (PubMed:22194193, PubMed:31691806).  Binds to specific sequence motif 5'-TAATTA-3' in regulatory elements of target genes, such as histone demethylase KDM5C (PubMed:22194193, PubMed:31691806).  Positively modulates transcription of KDM5C (PubMed:31691806).  Activates expression of KDM5C synergistically with histone lysine demethylase PHF8 and perhaps in competition with transcription regulator ZNF711; synergy may be related to enrichment of histone H3K4me3 in regulatory elements (PubMed:31691806).  Required for normal brain development (PubMed:11889467, PubMed:12379852, PubMed:14722918).  Plays a role in neuronal proliferation, interneuronal migration and differentiation in the embryonic forebrain (By similarity).  May also be involved in axonal guidance in the floor plate (By similarity).
What are the official names of this protein?
Homeobox protein ARX, Aristaless-related homeobox.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family. Bicoid subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: EFG_UREU1
Sequence: MSKELKLFRNFGIMAHIDAGKTTTSERILYHTGKNHKIGETHDGAATMDWMAQEKERGITITSAATYAKWKGHSLNLIDTPGHVDFTVEVERSLRVLDGAVAVLDGQNGVEPQTETVWRQATKYNVPRIVFVNKMDKTGADFYYSIETMKNRLGVKATAIQIPIGAEADFVGSIDLIEMKAYIYDGQADEEYKIEDIPADYVTKAQVMRSQMIDDVAIFDDEVMEKYLSGEELSHEDIKKCIRKGVISTELYPVLCGTAFKNKGVKKLLDAVVDFLPSPIDVPPIKGVDDHGNPIEYHNDPSEPFAALAFKVATDPFVGRLTYIRVYSGKLDKGTYVYNATKDKKERISRLVKMHSNNRDEIDSISAGDICAVIGLKDTTTGDTICDEKKPVILEQMVFAEPVISLSVEPKTKADQEKMSLALSKLAEEDPTFRTYTNEETGQTIIAGMGELHLDVLVDRMRREFNVQVNVGAPQVSYRETFTEIADAEGKYIKQSGGRGQYGHVWIKFEPNHDKGFEFVDNIVGGKVPKEYIKEVENGLIEALTSGPIAGYQTIDVKATIFDGSYHDVDSSGMAYKIAASLAFKEAAKVCKPVLLEPIMSVDVTTPDDYFGTVMGDISKRRGVIEGQEQRGNAQAIKAKVPLSEMFGYATDLRSNTQGRGQYIMQFSHYAQAPKSVTEEVMAARAKK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADE_HELPS
Sequence: MQKDYQKLIAYLCDFLEKEAQKRGFKKVVYGLSGGLDSAVVGVLCQKVFKKNAHALLMPSSVSMPESKTDALDLCETFSIPYTEYSIAPYDAIFNSHFKDASLTRKGNFCARLRMAFLYDYSLKSDSLVIGTSNKSERMLGYGTLFGDLACAINPIGELFKTEVYELACHLNIPKKILNKPPSADLFVGQSDEKDLGYPYSVIDPLLKDIEALFQNKPIDAETLAQLGYDEILVKNIISRIQKNAFKLELPTIAKRFNPK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: HLDE_ACTPL
Sequence: MIQYSSKFNNAKVLVLGDVMLDRYWFGATNRISPEAPVPVVKVQGIEERAGGAANVAMNIASLSVPVALHGLIGQDDAGRALDKLLNSHNIQNHCVALDSHPTITKLRILSRHQQLLRLDFEEGFHHVASDSLLAKLEQEITAYGALILSDYGKGTLESVQQMIQVARKAGVPTLIDPKGTDFERYRGATLLTPNMSEFEAVVGHCKDDDEIVEKGLKLIADFELTALLVTRSEKGMTLLRPNQAPFHLPTQAKEVYDVTGAGDTVISVLATAIADGRPYEEACYLANAAAGVVVGKLGTSTVTPTELENAIHHREETGFGILAEDELKRAVEQAKQRGEKIVMTNGCFDILHPGHVSYLENARKLGDRLIVAVNTDESVKRLKGESRPINDLNARMAVLAGLASVDWVVPFAEDTPQRLIGEILPNLLVKGGDYKPEEIAGSQEVWANGGEVKVLNFENGCSTTNVIKKIQASK
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: Y544_LACLS
Sequence: MNSLLIMGYTSFDLGIFNEKDIKVSIIKKTIRRKLINFLEEGLRWVIFTGNLGFEYWALEVAKELQTDYEFQIGTIFPFETHGQNWNENNQIKLASFKQVDFVKYAFEAYENPGQFRQYNEFLLENTEGSFVFYDEENETKLKNMVEKMKQSSNYEVYLLNFEDLQEIFEEMND
What are the official names of this protein?
UPF0398 protein LACR_0544.
What is the protein family that this protein belongs to?
Belongs to the UPF0398 family.
Protein: C3H7_ORYSJ
Sequence: MEEPSPVPPAAAPASLAAAPPTTDVLSRRRAHLDSASYRALSRLFSHCLHLHPPRHAARPDAEVEPAAAAAIPPGGSGGLPHGDSPPPADVGGDRGKNLEVEVALGNHAPHETPSTSASPDAAVNPTTDPGVVPQGTEEGRVAGVERVEGVEEVVFAGGTSGEADADGDELGAGAGLMGDDEALRSMQACLDGEDSELVIEMVGNDNEQLQLDAMMNNLSGLIDDASACVMSAQSCGVSGDKLQSDDRVAEEVKELGAGIGNDRSVCSLDHGSLDGGGGFEEGEIEGDTQNLDADDSGNSELQDDVELEEDFDSRRIEEDGSCGHDLKSNLHLIPQKGNGDTARNMLCNSKGDSQMHVARAQAVSYDEVLDWNETPLPDDKALKHGNTRKRTLTEERKAKKTKTKRIKRALQREAEGVKRLKLQPVIKPKVVKVCHFYLHGKCQQGNLCKFSHDTTPLTKSKPCTHYARGSCLKGDDCPYDHELSKYPCHNFMENGMCIRGDKCKFSHVIPTAEGPSTPDAKKSNASSVPEKANCQEQTSRQKTSTVYSGEPATSVPIKHHSILKNLAGISGNAQKVPVRIPRGIQFLPFNKARPDSSILHQDVVSTEKHKNPTGGPHQNFGRPQPADGKKLGKHNGHRSAPLLDEKDSSKQANLHPCSEPKKNSLPTTAAVPSSVSTQHEVSEASRILQEFLFGSGN
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 7, OsC3H7.
Protein: Y1314_HAEIN
Sequence: MKVYKSFLIATASLFLFACSSFQNDDYAMNYKGQIGEPIMAIAMLSEQQHEWAGTPYVLGGVSRRGVDCSGFVQKTFFDRFNLRLPRSTVEQANYGKHVRKEDIQTGDLIFFKTGRGPNGYHVGIYVKEDKFLHASTRGGVVYSSMNNPYWSKAFWQVRRI
What are the official names of this protein?
Probable endopeptidase HI_1314.
What is the protein family that this protein belongs to?
Belongs to the peptidase C40 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: RL30_DEHM1
Sequence: MAKIKITWVKSAIGYKFDQAATIKALGFKKLNQSVIQDDSAAIRGMILKVRHLVVLEEVT
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: EFTS_SCHPO
Sequence: MLFQRRLHFHQFFGKTRVTGSLSRQWYSKLPSKLADIKKLRSETNASMDLVKQSVEEAGVGNLELAREILKKKIVQRGGKLAEKSKNRTAKEGWIIQCISEDGRKAVMAEINCESDFVAQTTPFQDLARRIASTFLHYLPTNHSSYSVEATLKNEILKHQAYVSKNHEANEKDVSSNVSLEEEIVKMTSFTGEKVQVQRLHCMNARVPSTAIGIFSHGAKQSSPLQQLGRIGSMVQINSDLSTRKGLSNQIAKEIVAQDPSSTSELLSFRSLVDSEKTIKDVLGQSTILEWVRWERGGN
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, mitochondrial, EF-Ts, EF-TsMt.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: M1330_ARATH
Sequence: MLPAGCWNDTSRDGPGFRKMKGPKVEIGGYKFPISLGAENESTSRCDTAFSFLVGKERRSPSEPNRPMKNKRRAKPNGEAHAEQARRKISVEEKQPSSFPSHPGPKAVQSFLAKSRIWGFLLRYLTI
What are the official names of this protein?
Uncharacterized mitochondrial protein AtMg01330, ORF107h.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL24_KOSOT
Sequence: MGMRIKKDDTVKVISGEYKGKIGKVLKTLPKEGKVIIEGVNFTKRHQRPTNQYREGGIIEREAPIYACKVMVVCPNCDKPTRVGHKKLESGEKVRVCKKCGEIIDKV
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: RL13_PSYA2
Sequence: MKTLSAKPAEVTHDWYVVDADGKTLGRLATQIATRLRGKHKTCFTPHVDTGDFIVVINAEKIAVTGKKAQDKKYYRHSGYPGGIKETNFTKLIAHKPEDVLHKAVKGMLPKGPLGYAMIKKLKLYAGTEHPHEAQQPKELDI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.