PharMolix/UniProtQA huggingface dataset:
Protein: DAPA_RICCK
Sequence: MHNIFKGLITAAITPFKDNTLDLDALEKILEHQIKYEVDGVLIAGSTGECSNLSFEEYKLLLQTSLEIVNKRIPIISGCSSNNTAYARELAAESTKIGVDGFMASPPSYIKPTQEGIYKHFEALHEACNIPIMLYSAPTRSGVDFSDETILRLSKLSRILALKDCGVDLERPMRIRTIVKEDFNLLTGNDEVVLAFNAQGGVGWVSVASNIVPNICKELLEKWYKNDVKEALEIHQRLLPLYKALFVESNPIPIKYAAHYLGLCANKIRLPLTEASYKTKKQIENIITSLSIKI
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEP2_RAT
Sequence: MKHPAYTLLLSLIMSMCAGSKGLAEQLTKENLTVSLLPPNFHKENTVTNDWIPEGEEDDDYLDLEKLLSEDDDYIYVVDAVSPTDSESSAGNILQLFQGKSRIQRLNILNAKFAFNLYRVLKDQATSSDNIFIAPVGISTAMGMISLGLRGETHEEVHSVLHFKDFVNASSKYEVTTIHNLFRKLTHRLFRRNFGYTLQSVNDLYIQKQFPIREDFKAAMREFYFAEAQEADFSDPAFISKANSHILKLTKGLIKEALENTDSATQMMILNCIYFKGAWMNKFPVEMTHNHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGGISMLIVIPRKLSGMKTLEAQLTPQVVERWQKSMTNRTREVLLPKFKLEKNYNLVEVLKSMGITKLFNKNGNMSGISDQRIIIDLFKHQSTITVNEEGTQAAAVTTVGFMPLSTQVRFTVDRPFLFLVYEHRTSCLLFMGRVANPAKS
What is the function of this protein?
Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate.  In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT) (By similarity).
What are the official names of this protein?
Heparin cofactor 2, Heparin cofactor II, HC-II, Protease inhibitor leuserpin-2, Serpin D1.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
Protein: ISPD_ORYSJ
Sequence: MELRLCLRLHAPPASAPTTHPPPPLSPSPNLALRRLRTGGSCAVAPRRHARKWGSAVCAAKADGAQGEAVKERSVSVVLLSGGQGKRMGASMPKQYLPLLGLPIALHSLKTFCQLKEVKEVVVVCDPDYKDIFEGSIENVQIPIKFALPGKERQDSVYNGLQEIDGDSELVCVHDSARPLVSSEDVKKVLEDAIVHGAAVLGVPVKATIKEADSNSFVVKTLDRKTLWEMQTPQVMRPSLLRDGFELVKRDGLEVTDDVSIVEYLKHSVYITEGSYTNIKVTTPDDLLLAERLMNEK
What is the function of this protein?
Enzyme of the plastid non-mevalonate pathway for isoprenoid biosynthesis that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).  Is essential for chloroplast development (By similarity).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, OsCMS, MEP cytidylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: P5CR_SHIFL
Sequence: MEKKIGFIGCGNMGKAILGGLIASGQVLPGQIWVYTPSPDKVAALHDQFGINAAESAQEVAQIADIIFAAVKPGIMIKVLSEITSSLNKDSLVVSIAAGVTLDQLARALGHDRKIIRAMPNTPALVNAGMTSVTPNALVTPEDTADVLNIFRCFGEAEVIAEPMIHPVVGVSGSSPAYVFMFIEAMADAAVLGGMPRAQAYKFAAQAVMGSAKMVLETGEHPGALKDMVCSPGGTTIEAVRVLEEKGFRAAVIEAMTKCMEKSEKLSKS
What is the function of this protein?
Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
What are the official names of this protein?
Pyrroline-5-carboxylate reductase, P5C reductase, P5CR, PCA reductase.
What is the protein family that this protein belongs to?
Belongs to the pyrroline-5-carboxylate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OHRL_STAA8
Sequence: MAIHYETKATNVGGRKGHVYTDDRALDIDIVPPAQADGKATNPEQLFAAGYASCFNGAFDLILKQNKVRDAHPEVTLTVRLEDDSDSESPKLSVSIDATIKNVISQEEAEKYLQMAHEFCPYSKATQGNINVDLNVNVVD
What are the official names of this protein?
Organic hydroperoxide resistance protein-like.
What is the protein family that this protein belongs to?
Belongs to the OsmC/Ohr family.
Protein: AKRCA_ARATH
Sequence: MAEEIRFFELNTGAKIPSVGLGTWQADPGLVGNAVDAAVKIGYRHIDCAQIYGNEKEIGLVLKKLFDGGVVKREEMFITSKLWCTYHDPQEVPEALNRTLQDLQLDYVDLYLIHWPVSLKKGSTGFKPENILPTDIPSTWKAMESLFDSGKARAIGVSNFSSKKLADLLVVARVPPAVNQVECHPSWQQNVLRDFCKSKGVHLSGYSPLGSPGTTWLTSDVLKNPILGGVAEKLGKTPAQVALRWGLQMGQSVLPKSTHEDRIKQNFDVFNWSIPEDMLSKFSEIGQGRLVRGMSFVHETSPYKSLEELWDGEI
What is the function of this protein?
Oxidoreductase that may act on a broad range of substrates such as ketosteroids, aldehydes, ketones and sugars.
What are the official names of this protein?
Aldo-keto reductase family 4 member C10.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
Protein: C3H23_ARATH
Sequence: MMIGENKNRPHPTIHIPQWDQINDPTATISSPFSSVNLNSVNDYPHSPSPYLDSFASLFRYLPSNELTNDSDSSSGDESSPLTDSFSSDEFRIYEFKIRRCARGRSHDWTECPFAHPGEKARRRDPRKFHYSGTACPEFRKGSCRRGDSCEFSHGVFECWLHPSRYRTQPCKDGTSCRRRICFFAHTTEQLRVLPCSLDPDLGFFSGLATSPTSILVSPSFSPPSESPPLSPSTGELIASMRKMQLNGGGCSWSSPMRSAVRLPFSSSLRPIQAATWPRIREFEIEEAPAMEFVESGKELRAEMYARLSRENSLG
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 23, AtC3H23, Protein ATCTH.
Protein: MON1_EMENI
Sequence: MDTKDSNSSQALAIDGGAQTRPTDDHASLTKRLTQPRSDRSQSPEGRPPPLPPRPETLILLEDGGAAPGTPRPNVSAVHPGLQSRATTAVSLAEISQNDRGKDALAVRSFPGTVRAKASLSHLATPKDGSDAGDSASVTSYVPYSESGDVENIFGSLASSEVGIAQEESTGLMQFPEFQADDVEDDFASELEPVGEIGEGGENEGTVLAYGSTTAETDQLIDLVLEKWKAKRKHYIILSAAGKPIWTRHGDGGLISTYVGIIQTIISSYEDSNDRLNGFTAGDTKFTVVAKGPLYLVAISRILESDTQLKLQLEALYMQILSTLTLPALTHLFSVRPSTDLKRPLQGSETLLSTLADSFTKGSPSTLLSALECLKIRKSHRQTINNTLLKTKVSKLLYGLVVAGGRLVSVVRPKKHSLHPGDLQLLFNMIFEAEAVKAGGGESWIPVCLPGFNSSGYLYIFFELQAMKNALVEKLEENGSINNIKEAIDKGRPSTTDIVPGSVLHHFVYKSRVNVQFIMSAYDPEFSTITRRRRLISTYNNLHASVHAKHTHVKVHHCVTQSSSSFAWITPVFELYCVAGPHANRNALAQSASKVVQWVQKEEERLFIISGAVF
What is the function of this protein?
Required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis.
What are the official names of this protein?
Vacuolar fusion protein mon1.
What is the protein family that this protein belongs to?
Belongs to the MON1/SAND family.
What are the subcellular locations of this protein?
Endosome, multivesicular body membrane; Peripheral membrane protein. Prevacuolar compartment membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein.
Protein: PRHD_PENBI
Sequence: MHQLLENLSGNGMGLLIPLGLSWLIWTILLPKQQYRGKLFNDRARFEWFYTKARRRFLENGGVILNNAFKKSENSFYVMTSREVEIVLNPKYMNEVRNDDRFAVTERVDQLLHGDVPGFGIIKHSAQTHKIFSNTFQSRVVREIGTFLVPIFEEIDHFLETQWTDNEEWHAFSLHPSMVQLVSQESTRLFLGPEMCRDAHWLQASVKYIQSFFMGIDLLDSWRPIFRPLVSKFSKTGKQIRSDLAEARQILSPFIADRQARKAKGEKFNDLLQWFDDAARGAEYDAPLLILRSSMAAVHSTSDLLTKAIFEICTQPGLIDDIREEAIRVFKEHGLRQTAIQELRLTDSVLKETQRLKPLQTTAFIRLTKEDVVLSDGLEIPKGTPIRISNHHMWDPEVSEYPNADQFDGYRFYKLRQVPGQEQTAQLATVSPSHTGFGLGKHACPGRFFAATATKVILCKILLDYDLKLLDGQRPKTMWRGDAQVPDPMCQIVVRRRKEEFNLSSLLHDVK
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of paraherquonin, a meroterpenoid with a unique, highly congested hexacyclic molecular architecture (PubMed:27602587).  The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid (DMOA) by the polyketide synthase prhL (By similarity).  Synthesis of DMOA is followed by farnesylation by the prenyltransferase prhE, methylesterification by the methyl-transferase prhM, epoxidation of the prenyl chain by the flavin-dependent monooxygenase prhF, and cyclization of the farnesyl moiety by the terpene cyclase prhH, to yield the tetracyclic intermediate, protoaustinoid A (By similarity).  The short chain dehydrogenase prhI then oxidizes the C-3 alcohol group of the terpene cyclase product to transform protoaustinoid A into protoaustinoid B (PubMed:27602587).  The FAD-binding monooxygenase prhJ catalyzes the oxidation of protoaustinoid B into preaustinoid A which is further oxidized into preaustinoid A1 by FAD-binding monooxygenase phrK (PubMed:27602587).  Finally, prhA leads to berkeleydione via the berkeleyone B intermediate (PubMed:27602587, PubMed:29317628).  PrhA is a multifunctional dioxygenase that first desaturates at C5-C6 to form berkeleyone B, followed by rearrangement of the A/B-ring to form the cycloheptadiene moiety in berkeleydione (PubMed:27602587, PubMed:29317628).  Berkeleydione serves as the key intermediate for the biosynthesis of paraherquonin as well as many other meroterpenoids (Probable).  The cytochrome P450 monooxygenases prhB, prhD, and prhN, as well as the isomerase prhC, are probably involved in the late stage of paraherquonin biosynthesis, after the production of berkeleydione (Probable).  Especially prhC might be a multifunctional enzyme that catalyzes the D-ring expansion via intramolecular methoxy rearrangement, as well as the hydrolysis of the expanded D-ring (Probable).
What are the official names of this protein?
Cytochrome P450 monooxygenase prhD, Paraherquonin biosynthesis cluster protein D.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ILVD_ECO27
Sequence: MPKYRSATTTHGRNMAGARALWRATGMTDADFGKPIIAVVNSFTQFVPGHVHLRDLGKLVAEQIEAAGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDQIIKLDLVDAMIQGADPKVSDSQSAQVERSACPTCGSCSGMFTANSMNCLTEALGLSQPGNGSLLATHADRKQLFLNAGKRIVELTKRYYEQDDESALPRNIASKAAFENAMTLDIAMGGSTNTVLHLLAAAQEAEIDFTMSDIDKLSRKVPQLCKVAPSTQKYHMEDVHRAGGVIGILGELDRAGLLNRDVKNVLGLTLPQTLEQYDIIVTQDDAVKNMFRAGPAGIRTTQAFSQDCRWDTLDDDRSNGCIRSLEHAYSKDGGLAVLYGNFAENGCIVKTAGVDDSILKFTGPAKVYESQDDAVEAILGGKVVAGDVVVIRYEGPKGGPGMQEMLYPTSFLKSMGLGKACALITDGRFSGGTSGLSIGHVSPEAASGGSIGLIEDGDLIAIDIPNRGIQLQVSDAELAARREAQEARGDKAWTPKNRERQVSFALRAYASLATSADKGAVRDKSKLGG
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: GATC_CLOBL
Sequence: MSVSKKDVEYVAELARLEFKEEEKDNFVNDLNKILNYMEKLDELNTDDVDIVVNPYYIENKYREDNVEKSMELKEVIDNAPESLEEYVIVPKVID
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: RF3_FRATM
Sequence: MSEYLQQIAKRRTFAIISHPDAGKTTITEKMLLFGNAIKTAGTVKAKKSGIYATSDWMEMEKQRGISITTSVMQFPYNGRIINLLDTPGHEDFSEDTYRTLTAVDSALMVVDAVKGVEDRTIKLMNVCRLRDTPIVTFMNKFDRDTRDPLELLDEVENILKIKCAPMNWPIGMGKYFKGVYDLYNDEVTLFETGHGHEIYPYKKIKGLANAKDAIGIDLYEDLEMEIDLVRGASHEFDEQEFLEGNLTPVYFGTALSNFGVKEMMDGFTRYAPAPQHREADQRVVAADEQKLTGFVFKIQANMDEKHRNRIAFFRICSGKYEKGMKIFHERTGKQMQISKALTFMAGEREQVEEGYAGDIIGLHNHGSIQIGDSFTQGEKLKFKGIPNFAPEIFKRVKLNDPLKMKALQKGLVQLSEEGATQVFKPFISNDLVLGAVGVLQFDVVAQRLASEYNVKCSYEGVNVTLARWIFCSDEKKLNDFKKKYEVNLAYDGAGYLTYLAPTGVNLQLAQEKNPDIIFSATREH
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THEM6_MOUSE
Sequence: MLELLVASLSLALAFFALLDGWYLVRVPCAVLRARLLQPRVRDLLAEQRYAGRVLPSDLDLLLHMNNARYLREADVARAAHLTRCGVLGALRDLNAHTVLAASCARYRRSLRLFEPFEVHTRLQGWDDRAFYLEARFVSLRDGFVCALLRFRQHVLGTSPDRVVQHLCKRRVEPPELPEDLKHWISYNETSSQLLRAESGLSDRKDQ
What are the official names of this protein?
Protein THEM6.
What is the protein family that this protein belongs to?
Belongs to the THEM6 family.
What are the subcellular locations of this protein?
Secreted.
Protein: KATG_SHEDO
Sequence: MSENKCPVMHGSATTTENSMANMNWWPKSLSLDILHQHDHKTNPMAADFNYQDEVKKLDFVALKNDLHALMTDSQAWWPADWGHYGGLMIRLTWHAAGTYRIADGRGGAGHGSQRFAPLNSWPDNGNLDKARRLLWPIKKKYGNKLSWADLIAYAGTIAYESMGLKTFGFAFGREDIWHPEKDIYWGAEKDWLLPTDNDNSRYSGERNLENPLAAVMMGLIYVNPEGVDGKPDPLKTAQDIRETFARMAMNDEETVALTAGGHTVGKAHGNGNADLLGPEPEDADIHDQGFGWLNKAKRGIGRDTVTSGIEGAWTTHPTQWDNGYFTMLLNHEWELCKSPAGAWQWQPINIKEEDKPRDVEDPSISTMPMMTDADMAMKMDPEYRKISEHFHRDPEYFSKVFSRAWFKLTHRDMGPKVRYLGPDVPVEDLLWQDPVPTGPKDFNVAVVKKAIKETGLSISDMVTTAWDSARTFRGSDKRGGANGARIRLALQKQWAGNEPKRLASVLSVLEPIAASHGVSVADVIVLAGNLGIELAAKKAGFDVTVPFISGRGDATDEMTDNESFAVLEPLHDGYRNWLKQDFAVSAEELMLDRTQLMGLTAHEMTVLVGGMRVIGTNYAETGHGVFTERKGALTNDFFVNLTDMNYIWKPIGQNEYEICERETGKRKWTASRVDLIFGSNSVLRSYAEVYAQDDNKQKFVNDFISAWTKMMNADRFDVS
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: HBX3_ECHGR
Sequence: RIHPCPVNKCKCSRAPGRSLSYSKRIINEIRQNPSKCQIFFYQTSPPPSLAPYPLQRLRPYPSSMNPRDLEMVVVTNFQSQSKRRVLFNKFQISQLEKRLKQRYLTAQERQELAHTIGLTPTQVKIWFQNHAYKMKRLFHDDHVEASVHKWPIKSAHLQPKVSTRVV
What are the official names of this protein?
Homeobox protein EgHBX3.
What is the protein family that this protein belongs to?
Belongs to the NK-2 homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PTC71_DROGR
Sequence: MFFKVCQLGKGRCCQVLLNYASCQRCQLSSYKGTPRLIKAVQGSSKDQQLAGQVQRFGEDSWFVHSAPKSETMGVADGVGGWRQMGIDSGVFAKQLMTNCSKLSEQADYDGRNPRQLLIDGYHRLKEHATNVWGSSTACLVSLHRSDCTLHSANLGDSGFLVLRHGKVLHRSDEQLHVFNTPYQLSVPPTSQMHKVLSDQPEEAICTQLGLQQGDLVLVATDGLFDNVVESELVQQLQQLHGETRVEKVQLAANRLVDLAKRLSLRTDYQSPFALRAKANNMNYGAGGKPDDITVILASVEVSQRSN
What are the official names of this protein?
Protein phosphatase PTC7 homolog fig, Fos intronic gene protein.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: IQUB_RAT
Sequence: MSDTEENVLDSPASGEAAGEVISIPGPTDEAEESDISPEQEYEIEGFTTESEETVEHYSDLSVSTPKSYDSKPRDEVVSLGSATDSHEQEYRLGDLGGDQRSEEDEMSFLYKIKAIKENLQSSVKECIATVKIVLIPAGQEIVMPFRVDAPFRFLKEHFAHLLRIPHHVLQMAYTGISVGNNESLIQYGVKPREIVQMNVFSSEPDQYPVRRIEGLSEGSKIITVTIQTGIERYEEVAVEIVKSDFHKPFLGGFRHKITGLEYHNAGTQTVPKKIPEKDNLFCRDTQTVFQKKKLQQTMNTTSTQMTKIGVYVSNMTDKLLTPGSYFSAAEYHARRLNAVIVIQTAYRRWHAKCYVDSLRLQKKMRLEWEKEEELKKIREKEEWIRMDYYRRHNPKTTEDFELLFNALELWRQEEVTQVEQYSSEAERKAALCELLEKETQIIASIGRHRYVAQLERQDVATQAFLDKCSASNTWRRPDGQTVEMDTQFTIRARELQSIYKCILLKNLSQDERLDILLTLKHTVKEHECKLTQEILELIDREVDLMMRGVKSHNLEGLRKRITTLFIHYIKTPLFNPEVAKHLKVPQDPLKFYDKIYFCHSCQMYLPSVEFSVSPTSHRVYRCRHCINLENETQRRESFLKYKCLLQRLYFSEANYEDNSHIAYLMQLQDIKYLTENIWASQSALSAWDDLNDLVMVRWNKHVEWSPWNCILLTKDEGTAHLKLESIEKGYGRLFIHKIKHKHILAKNYFSQVPVLASLILKDDEIEAIRSKYSTENPPKIIVPHGIVPN
What is the function of this protein?
Adapter protein that anchors the radial spoke 1 (RS1) complex to the A microtubule of outer doublet microtubules in axonemes.  The triple radial spokes (RS1, RS2 and RS3) are required to modulate beating of the sperm flagellum.  May play a role in inhibiting signaling via MAPK1/ERK2 and MAPK3/ERK1.  Additionally, may play a role in the functioning of cilia.  Not required for the functioning of tracheal or ependymal cilia.
What are the official names of this protein?
IQ and ubiquitin-like domain-containing protein, Protein TRS4.
Protein: LOLB_ALKEH
Sequence: MRRGRLLIAGLAALVLSACATLPEPVDDPKARYQEAVERLRAQTDWDASGRAALRTADDAGSLSLEWRQRGETYQVDLRAPLGAGSARLEGGPEGVWLTTSAGDREYAPDPETLVAWFTGYQVPVSALRYWLRGLDAPGPEVERLDLDPAGRPERLHQAGWEVVYRDWSQTNGLPLPRRLDISRGEDSVRVVIRDWSLAP
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: DHB3_MOUSE
Sequence: MEKLFIAAGLFVGLVCLVKCMRFSQHLFLRFCKALPSSFLRSMGQWAVITGAGDGIGKAYSFELARHGLNVVLISRTLEKLQTIAEEIERTTGSCVKIVQADFTREDIYDHIKEHLEGLEIGILVNNVGMLPSFFPSHFLSTSGESQNLIHCNITSVVKMTQLVLKHMESRRKGLILNISSGAALRPWPLYSLYSASKAFVYTFSKALSVEYRDKGIIIQVLTPYSISTPMTKYLNNKMTKTADEFVKESLKYVTIGAESCGCLAHEIIAIILNRIPSRIFYSSTAQRFLLTRYSDYLKRNISNR
What is the function of this protein?
Catalyzes the conversion of 17-oxosteroids to 17beta-hydroxysteroids (PubMed:32557858).  Favors the reduction of androstenedione to testosterone (PubMed:32557858).  Testosterone is the key androgen driving male development and function (PubMed:32190925, PubMed:32557858).  Uses NADPH while the two other EDH17B enzymes use NADH (By similarity).  Androgens such as epiandrosterone, dehydroepiandrosterone, androsterone and androstanedione are accepted as substrates and reduced at C-17.  Can reduce 11-ketoandrostenedione as well as 11beta-hydroxyandrostenedione at C-17 to the respective testosterone forms (By similarity).  Plays a role in the rate-limiting-step for the maximum level of testosterone production by the testis but does not affect basal testosterone production (PubMed:32190925, PubMed:32557858).
What are the official names of this protein?
17-beta-hydroxysteroid dehydrogenase type 3, 17-beta-HSD 3, Estradiol 17-beta-dehydrogenase 2, Testicular 17-beta-hydroxysteroid dehydrogenase, Testosterone 17-beta-dehydrogenase 3.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: RIBB_SALEP
Sequence: MNQTLLSSFGTPFERVELALDALREGRGVMVLDDEDRENEGDMIFPAETMTVEQMALTIRHGSGIVCLCITEDRRKQLDLPMMVENNTSAYGTGFTVTIEAAEGVTTGVSAADRVTTVRAAIKDGAKPSDLNRPGHVFPLRAQAGGVLTRGGHTEATIDLMTLAGFKPAGVLCELTNDDGTMARAPECIAFAGQHNMAVVTIEDLVAYRQAHERKAS
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: GSA_CITK8
Sequence: MSKSENLYSAARELIPGGVNSPVRAFTGVGGTPLFIEKADGAYLYDVDGKAYIDYVGSWGPMVLGHNHPAIRNAVIEAAARGLSFGAPTEMEVKMAELVTELVPTMDMVRMVNSGTEATMSAIRLARGFTGRDKIIKFEGCYHGHADCLLVKAGSGALTLGQPNSPGVPADFARHTLTCTYNDLASVRAAFEQYPQEIACIIVEPVAGNMNCIPPQPEFLPGLRALCDEFGALLIIDEVMTGFRVALAGAQDYYGVVPDLTCLGKIIGGGMPVGAFGGRRDVMDALAPTGPVYQAGTLSGNPIAMAAGFACLTEVAQPGIHETLDELTTRLAEGLLDAAQEADIPLVVNHVGGMFGIFFTDAESVNCYQDVMACDVERFKRFFHMMLDEGVYLAPSAFEAGFMSVAHSMDDINNTIDAARRVFAKL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_STAAC
Sequence: MSAIIEAKKQLVDEIAEVLSNSVSTVIVDYRGLTVAEVTDLRSQLREAGVEYKVYKNTMVRRAAEKAGIEGLDEFLTGPTAIATSSEDAVAAAKVISGFAKDHEALEIKSGVMEGNVITAEEVKTVGSLPSHDGLVSMLLSVLQAPVRNFAYAVKAIGEQKEENAE
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: COAE_RHOPA
Sequence: MLVLGLTGSIGMGKSTTAKLFAEAGVPVYDADATVHKIYENEAVPAIEAAFPGTTLGGKVDRALLSAKVVHDPAAMKRLEGIVHPMLRAHHQQFLDDAESSGAPVAVVDVPLLFETGGEKRVDAVVVVTTSPEVQRERILARDNMTPEKLDAILARQMPDAEKRKRADFVVDTSNGLDPVRLQIREILEAAAKMPRRRD
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_DEHMC
Sequence: MVQQYTRLNVADNTGAKKIMCINVLGGSHKIQAKVGDVIVAAVKKSSPDAQAKSGTVVKAVVVRITKPYARPDGSYIKFDDNAAVILNDKMEPKGTRIFGPVARELRDKKFTKILSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: HIS6_SULSY
Sequence: MLAKRIIPCLDVDKGRVVKGVNFVNLIDAGDPVEIASVYDKEGADELVFLDITASSEDRNIILDVVKKTAETVFMPLTVGGGVRSLEDIRKLLENGADKVSINTAAVKNPSLVENAAIRFGSSTIVVAIDAKKVGENKWEVYIHGGRTPTGIDAIEWAKAVESLGAGEILLTSMDKDGTKSGYDIELTKAVSEAVKIPVIASGGAGNVQHFYEAFEYGKADACLAASLFHFKEIEISELKNYLKNKGINVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31_CLOK1
Sequence: MKKGIHPEYYHDSVVKCACGNTFTTGSTQKELKVEICSKCHPFFTGKQKLVDAGGRVDRFLKKFNLKNEE
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: DGK1_ORYSJ
Sequence: MDGHTNGTNGSCSKPCEPLTDYCIPDYILNPDSEQVLVDQAPCCPVVVFINSRSGGQLGSSLIKTYRELLNKAQVFDLSEEAPEKVLHRLYCNFEKLKSNGDPIAFQIQSNLRLIVAGGDGTASWLLGVVSDLKLSHPPPIATVPLGTGNNLPFSFGWGKKNPTTDQEAVKSFLGQVKKAREMNIDSWHIIMRMRAPQEGPCEPIAPLELPHSLHAFHRVSGSDSLNMEGYHTYRGGFWNYFSMGMDAQVSYEFHSERKRNPEKFKNQLTNQSTYAKLGLKQGWFAASLTHPSSRNIAQLAKVRIMKRPGGQWEELKIPRSIRSIVCLNLPSFSGGLNPWGTPGTRKVQDRDLTAPFVDDGLIEVVGFRDAWHGLVLLAPNGHGTRLAQAHRIRFEFHKGAAEHTFMRIDGEPWKQPLPKDDDTVVVEISHLRQVTMLASDPCKSKSVNDPSSPMCCSNHDDDERNSLEDEDEWEEGRKKFGAADTFKFPDEVDVAHLS
What is the function of this protein?
Phosphorylates the second messenger diacylglycerol (DAG) to generate phosphatidic acid (PA), another important signaling molecule (PubMed:30887532).  PA is required for plant development and responses to abiotic stress (Probable).  May play a role in disease resistance responses to pathogen attack (Probable).  Modulates root architecture by regulating the ratio of DAG and PA, which have opposite effect on the promotion or suppression of lateral roots vs seminal roots (PubMed:30887532).  Suppresses lateral root number, but promotes seminal root and crown root thickness (PubMed:30887532).
What are the official names of this protein?
Diacylglycerol kinase 1, DAG kinase 1, OsDGK1, BTH-inducible diacylglycerol kinase 1, OsBIDK1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic diacylglycerol kinase family.