PharMolix/UniProtQA huggingface dataset:
Protein: NUON_ECO27
Sequence: MTITPQNLIALLPLLIVGLTVVVVMLSIAWRRNHFLNATLSVIGLNAALVSLWFVGQAGAMDVTPLMRVDGFAMLYTGLVLLASLATCTFAYPWLEGYNDNKDEFYLLVLIAALGGILLANANHLASLFLGIELISLPLFGLVGYAFRQKRSLEASIKYTILSAAASSFLLFGMALVYAQSGDLSFVALGKNLGDGMLNEPLLLAGFGLMIVGLGFKLSLVPFHLWTPDVYQGAPAPVSTFLATASKIAIFGVVMRLFLYAPVGDSEAIRVVLAIIAFASIIFGNLMALSQTNIKRLLGYSSISHLGYLLVALIALQTGEMSMEAVGVYLAGYLFSSLGAFGVVSLMSSPYRGPDADSLFSYRGLFWHRPILAAVMTVMMLSLAGIPMTLGFIGKFYVLAVGVQAHLWWLVGAVVVGSAIGLYYYLRVAVSLYLHAPEQPGRDAPSNWQYSAGGIVVLISALLVLVLGVWPQPLISIVRLAMPLM
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NDB51_MESEU
Sequence: MMKQQFFLFLAVIVMISSVIEAGRGREFMSNLKEKLSGVKEKMKNSWNRLTSMSEYACPVIEKWCEDHCQAKNAIGRCENTECKCLSK
What is the function of this protein?
The synthetic meucin-24 inhibits the development of P.  berghei ookinetes, kills intraerythrocytic P. falciparum, and is cytotoxic to the Drosophila S2 cell at micromolar concentrations.  No antibacterial, antifungal and hemolytic activities have been found at micromolar concentrations.
What are the official names of this protein?
Potassium channel toxin MeuTXKbeta3-meucin-24.
What is the protein family that this protein belongs to?
Belongs to the long chain scorpion toxin family. Class 2 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PXPA_CUPPJ
Sequence: MQIDLNADLGEGCGNDEALLALISSANVACGWHAGDAATMLQTVKWAIEKGVAIGAHPSFPDRENFGRTEMQRDPEAVYADVLYQIGALAAMVRAQGGQLHHVKPHGALYNQAARDPALAEAIVRAVRDFDSDLIFFGLAGSKMIDVARKAGLRVKEEVFADRGYNADGSLVKRGTPGALHEDEEVALNQTLTMVREQRVRAIDGNWVPIRAETVCLHGDGDHALAFARRIRERLGAEGIAVRAGA
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: MNMA_PECAS
Sequence: MSDNSQKKVIVGMSGGVDSSVSAYLLQQQGYHVEGLFMKNWEEDDDTEYCSAATDLADAQAVCDKLGIELHTVNFAAEYWDNVFELFLEEYKAGRTPNPDILCNKEIKFKAFLEFAAEDLGADYIATGHYVRRHDVDGKSRLLRGMDGNKDQSYFLYTLSHEQIAQSLFPVGELEKPQVRKIAEELELATAKKKDSTGICFIGERKFTDFLARYLPAQPGPILSVDDNKPMGQHQGLMYHTLGQRKGLGIGGVKDGGEDPWYVVDKDVANNILYVAQGHEHPRLMSYGLIAQQLHWVDRQPLTAELRCTVKTRYRQADISCTVTPLGDDRITVRFDEPFAAVTPGQSAVFYLDDVCLGGGIIEERLQE
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis.  Sulfur is provided by IscS, via a sulfur-relay system.  Binds ATP and its substrate tRNAs.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIE_MYCTA
Sequence: MHESRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAACEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHDPDQVAAAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQRLPAVLDAGARRIVVVRAITSADDPRAAAEQLRSALTAAN
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: CURS3_CURLO
Sequence: MGSLQAMRRAQRAQGPATIMAVGTSNPPNLYEQTSYPDFYFRVTNSDHKHALKNKFRVICEKTKVKRRYLHLTEEILKQRPKLCSYMEPSFDDRQDIVVEEIPKLAKEAAEKAIKEWGRPKSEITHLVFCSISGIDMPGADYRLATLLGLPLSVNRLMLYSQACHMGAQMLRIAKDLAENNRGARVLAVSCEITVLSFRGPDAGDFEALACQAGFGDGAAAVVVGADPLPGVERPIYEIAAAMQETVPESERAVGGHLREIGWTFHFFNQLPKLIAENIEGSLARAFKPLGISEWNDVFWVAHPGNWGIMDAIETKLGLEQGKLATARHVFSEYGNMQSATVYFVMDEVRKRSAAEGRATTGEGLEWGVLFGFGPGLTIETVVLRSVPLP
What is the function of this protein?
Catalyzes the synthesis of curcumin by condensing feruloyl-CoA with a diketide-CoA in the curcuminoid biosynthesis.  Also acts as a demethoxycurcumin synthase by accepting 4-coumaroyl-CoA as a starter substrate instead of feruloyl-CoA.
What are the official names of this protein?
Curcumin synthase 3, Demethoxycurcumin synthase.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: Y1514_BARHE
Sequence: MNTVTDETHAISVNQLRAFIERIERLEEEKKTISDDIKEVYAELKGSGFDSKAVRSIIRLRKKEEHERMEEEAIIQLYKDALGMS
What are the official names of this protein?
UPF0335 protein BH15140.
What is the protein family that this protein belongs to?
Belongs to the UPF0335 family.
Protein: SYLC_NOSCE
Sequence: MNCNEHESTKLNYLNSLEKSRDVKTDISDKPKYFITFPYPYMNGKLHLGHLYSISKADFMSYYKELQGFNVLFPLAFHCTGMPIAALAKKLGEELEGKKTDISTKEIIQNLGFNDVMPFTDPVHWIKTFPKLCISSLKTFGANIDWRRSFVTTDINKYYDSFVRWQFFNLKELGYLSFGKRHSIYCPLDKQMCLDHDRRKGENIKPVRQIMFKFHLHDKILLVRQNSIGKPYKLVCGKSLEVVSFKYNNTSFLAEKIIFDNLKYQINNVKYKESLVLSMDLKDGLTYDGTNIEVEVIEKNILVVKTDTKSDVELYEKEIKALNEIEETLFTLSTSSEGIVESVAKLSVENTKDLLVQTKHFISVYIPEKEVISRSGGICVVSLLDQWYIDYSNEKWKSKVKKCLDNLECGPDTRSMLYAGIDWVNKWGFSRSFGLGTKIPWDTQYLIDSLSDSTIYMAFYTVKHLLFEDLEGKLEIFPSNKLSNDVWDYIFAGKDLVPELYGYLDLLEKCRNNFQYFYPVDLRVSGKDLIKNHLLFFMFNHVALFDEKYWPKRIFTNGHLMLNKEKMSKSTGNFLSVDDALLKYGKSATRMCLAVCGDTNDDANFVEDNANLFILKIYTFVKEIQKLNELVRKKSENETIASYSNADVLLLETVSVNVTEALNAYNSMKYSDVVKFSFFEMVNLINLYNNINGTNILLKNLVYKSATQLLYPIMPDLCRTLIEKYFDSEFNLPEPKLKTNKMISAFEYISELIKKIAASKQAKNNSCVKIAVGKNYSEWKKEIFELIDKIDCPRNNEIKKNKVFIASLLDSVKPILQKSKINITKGNNFVMDYLVNPDKFVMKFNEYEIINEFKFYIENMSNKKAILEEHCDAEPLNPIITFSK
What are the official names of this protein?
Probable leucine--tRNA ligase, cytoplasmic, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IDS_MOUSE
Sequence: MSPPPPPPIWRQLSFSLLLGSFCIALESAAQGNSATDALNILLIIVDDLRPSLGCYGDKLVRSPNIDQLASHSVLFQNAFAQQAVCAPSRVSFLTGRRPDTTRLYDFNSYWRVHSGNFSTIPQYFKENGYVTMSVGKVFHPGISSNHSDDYPYSWSFPPYHPSSEKYENTKTCKGQDGKLHANLLCPVDVADVPEGTLPDKQSTEEAIRLLEKMKTSASPFFLAVGYHKPHIPFRYPKEFQKLYPLENITLAPDPHVPDSLPPVAYNPWMDIREREDVQALNISVPYGPIPEDFQRKIRQSYFASVSYLDTQVGHVLSALDDLRLAHNTIIAFTSDHGWALGEHGEWAKYSNFDVATRVPLMLYVPGRTAPLPAAGQKLFPYRDPFDPASDWMDAGRHTEDLVELVSLFPTLAGLAGLPVPPRCPIPSFHVELCREGQNLQKHLQLHDLEEEPDLFGNPRELIAYSQYPRPADFPQWNSDKPSLNDIKVMGYSIRTVDYRYTVWVGFDPSEFLANFSDIHAGELYFVDSDPLQDHNVYNDSQHGGLLHSLRP
What is the function of this protein?
Lysosomal enzyme involved in the degradation pathway of dermatan sulfate and heparan sulfate.
What are the official names of this protein?
Iduronate 2-sulfatase, Alpha-L-iduronate sulfate sulfatase.
What is the protein family that this protein belongs to?
Belongs to the sulfatase family.
What are the subcellular locations of this protein?
Lysosome.
Protein: RPN2_PONAB
Sequence: MAPLGSSTVFLLALTIIASTRALTPTHYLTKHDVERLKASLDRPFTNLESAFYSIVGLSSLGAQVPDAKKACTYIRSNLDPSNVDSLFYAAQASQALSGCEISISNETKDLLLAAVSEDSSVTQIYHAVAALSGFGLPLASQEALSALTARLSKEETVLATVQALQTASHLSQQADLRSIVEEIEDLVARLDELGGVYLQFEEGLETTALFVAATYKLMDHVGTEPSIKEDQVIQLMNAIFSKKNFESLSEAFSVASVAAVLSHNRYHVPVVVVPEGSASDTHEQAILRLQVTNVLSQPLTQATVKLEHAKSVASRATVLQKTSFTPVGDVFELNFMNVKFSSGYYDFLVKVEGDNRYIANTVELRVKISTEVGITNVDLSTVDKDQSIAPKTTRVTYPAKAKGTFIADSHQNFALFFQLVDVNTGAELTPHQTFVRLHNQKTGQEVVFVAEPDSKNVYKFELDTSERKIEFDSASGTYTLYLIIGDATLKNPILWNVADVVIKFPEEEAPSTVLSQNLFTPKQEIQHLFREPEKRPPTVVSNTFTALILSPLLLLFALWIRIGANVSNFTFTPSTIIFHLGHAAMLGLMYVYWTQLNMFQTLKYLAILGSVTFLAGNRMLAQQAVKRTAH
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit, Ribophorin II, RPN-II, Ribophorin-2.
What is the protein family that this protein belongs to?
Belongs to the SWP1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Endoplasmic reticulum membrane; Multi- pass membrane protein.
Protein: BIOB_CAMFF
Sequence: MLCAICNVSSGNCAEDCAYCTQSAHIKADIPKFKQKNLEQILNEAKIASKNYALGFCLVTSGLGLDDKKLEFICEAATMLRKETPNLMLIACNGSASYESLKELKKVGIFSYNHNLETSREFFPQICTTHSWDDRFNTNLNAKKAGLELCCGGIYGLGESQDDRLSFRASLKELNPFSSPINFFIPNPALKIKQPLLSTDEALEIIRDTAKTLPQCRIMVAGGREIVLGDRQYEILENGASAIVIGDYLTTSGEVASKDIEELRNRGFEFASQCH
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: Y001_HIS1I
Sequence: MNCEKCSGDMELQDSHYSYVSPTNRVAIKYYKCLECGNEMAIEE
What are the official names of this protein?
Uncharacterized protein ORF1.
Protein: PTPM1_DROME
Sequence: MEMSAAMFARVSFYPTLLYNVLMEKASARNWYDRIDEHVILGALPFRSQANDLIEKENMKAVVSMNEDYELTAFSNNTEKWRKLGIEFLQLATTDIFESPNQEKLFRGVEFINKFLPLKQRIGGLSSSYQPENVGSVYVHCKAGRTRSATLVGCYLMMKNGWTPDQAVDHMRKCRPHILLHTKQWDALRLFYTNNVETKS
What is the function of this protein?
Lipid phosphatase that may mediate dephosphorylation of mitochondrial proteins (By similarity).  Protein phosphatase that may mediate dephosphorylation of mitochondrial proteins (By similarity).  Does not dephosphorylate Akt.
What are the official names of this protein?
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1, PTEN-like phosphatase, PTEN-like protein, Protein-tyrosine phosphatase mitochondrial 1-like protein.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: Y523_CLOAB
Sequence: MEKVIPVKKNNDYEIYIDDFGNMGEGIGKIDNFTVFVKDAVKGEKVRAKIIKVNKSFAIGKLIDIIEKSQDRTEPVCSIYKKCGGCQLQHLKYTEQLEFKKNKVVECLKRIGKLDLSSVRINETIGMEDPYFYRNKVQLPVGETAGEAKIGFYRERSHEIIEVDKCFIQDDSANEIILLIKRWIKEFNIEGYNEYSGKGTLRHIMIRKAFKTGQIMLVLVTNTENVPHKKELIHMITTEIQGIKGIIQNINNKKTNVILGQREITLWGESTIEDYIGEFKFNISSKSFFQVNPIQTEKLYSAALKYAGLTGKEVVFDAYCGTGTISLFLSQNAKKVYGVEIIPEAIENAKINAKQNGIENTEFIVGKSEEEIPKLIEKGIAPEVVVVDPPRKGCEKSLLHSIAEASPKTIVYVSCDPATLSRDLGILSELGYEVNEVQPVDMFPMTGHVETIVLIKRVDK
What are the official names of this protein?
Uncharacterized RNA methyltransferase CA_C0523.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
Protein: UREG_RHILW
Sequence: MKSRNGPLRVGIGGPVGSGKTALTEKLCKAMRDNYSVAVVTNDIYTTEDAEALVRMQALPSDRIVGVETGGCPHTAIREDATINLQAIAGLNQRIPDLDVVFIESGGDNLAATFSPDLADITIYVISVCQGEEIPRKGGPGITRSDLLVINKKDLAPYVGADLEVMDRDATRMRASRPFVFSDMKRGDGVSSIVSFLREQGGL
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CALX_PONAB
Sequence: MEGKWLLCMLLVLGTAIVEAHDGHDDDVIDIEDDLDDVIEEVEDSKPDTTAPPSSPKVTYKAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVDEMKESKLPGDKGLVLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFHDKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKTHLYTLILNPDNSFEILVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPEAVKPDDWDEDAPAKIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPKCESAPGCGVWQRPMIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPDFFEDLEPFRMTPFSAIGLELWSMTSDIFFDNFIICADRRIVDDWANDGWGLKKAADGAAEPGVVGQMIEAAEERPWLWVVYILTVALPVFLVILFCCSGKKQTSAMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRKPRRE
What is the function of this protein?
Calcium-binding protein that interacts with newly synthesized monoglucosylated glycoproteins in the endoplasmic reticulum.  It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits.  It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins.  Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation.  Additionally it may play a role in receptor-mediated endocytosis at the synapse (By similarity).
What are the official names of this protein?
Calnexin.
What is the protein family that this protein belongs to?
Belongs to the calreticulin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endoplasmic reticulum. Melanosome. Note=The palmitoylated form preferentially localizes to the perinuclear rough ER.
Protein: GMHA_SOLM1
Sequence: MSENALRLIASYVEEAAAARARFFTDHAELVDAAARTMAVALARGGKILFCGNGGSAADAQHLAAEFVNRFELERPPLPALALTTDSSALTAIGNDYGFDRVFAKQVQALAGPSDVVVGISTSGNSPNVLAALRAARDKGCVTVGLAGRNGAIVPLCDYALLVPSDRTAHIQEVHATIGHLLCKLVDHYLFEAVMELGPYLEDH
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_RHOCS
Sequence: MAGNSFGTLFRFTTFGESHGPAIGCIVDGVPPRLPLDEAFIQGFLDRRRPGQSRFVTQRQEPDAVRILSGVFEGLTTGTPVMLEIVNQDQRSRDYGEIRDRFRPGHADWTYQAKYGIRDHRGGGRSSARETASRVAAGAVARRVLETAPAPVTVRGALVQVGPHRVDRARWDWAEVERNPFFCPDAGTAALWADYLDGVRKAGSSIGAVVEVVASGVPAGWGEPIYDKLDGDLARAMMTINAVKGVEIGAGFAAAELSGEENADEMRAGPDGQPLFLSNRAGGILGGISTGQDIVVRFAVKPTSSILTPRRTIDTAGHETEIVTKGRHDPCVGIRAVPVGEAMMACVLADHFLRHRALVGAPGPVGNGGPVEDGDPVGG
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: YO01_BPHC1
Sequence: MKNLFYALKEHWQIYVGLLLGLIIGLLVGVGFTDWKSLVRGLDSKVTDWISSLSTLIIMCFTAVGVMSWKKQKTPDLKSKVAKNIIDFDTHAVLLPSKKFQSIDEIKEYNAIQLKIFWDIEHSLSTLYMFDKSNKQEIDTILGYLLKDINSATSLIEKHARYDEVGRYQLVSLINNGYKNTYPNTTKLFELVVGKSNVVGLNGSS
What are the official names of this protein?
Uncharacterized 23.2 kDa protein in int-C1 intergenic region, ORF1.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: TOP2A_CHICK
Sequence: MELLDSPAPLRPLHDNPRLPKADGAQKRLSVERIYQKKTQLEHILLRPDTYIGSVETVTQQMWVFDEDVGLNCRDVTFVPGLYKIFDEILVNAADNKQRDKSMSCIKVTIDPENNTISVWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVETACREYKKLFKQTWTDNMGKAGEMTLKHFDGEDYTCVTFQPDLSKFKMTILDKDIVALMSRRAYDIAGSTKDVKVFLNGKRLPVKGFRSYVDLYLKDKVDETGNALKVIHEEVNSRWEVCLTLSEKGFQQVSFVNSIATTKGGRHVDYVADQIVTKLIDVVKKKNKNGVGVKPFQVKNHMWIFVNSLIENPTFDSQTKENMTLQAKSFGSTCKLSEKFIKGAVGCGIVESILNWVKFKAQTQLNKKCSAVKHTKIKGVPKLDDANDAGSKNSIDCTLILTEGDSAKTLAVSGLGVVGRDKYGVFPLRGKMLNVREASHKQIMENAEINNIIKIVGLQYKKNYEDRESLKSLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLRHNFLEEFITPIIKVSKNKEEIPFYSIPEFEEWKSSTQNYNSWKIKYYKGLGTSTSKEAKEYFADMARHRIGFKYSGPEDDAAITLAFSKKKVEERKEWLTNFMEDRRQRNVHGLPEDYLYGKDTNYLTYNDFINKELVLFSNSDNERSIPSLVDGLKPGQRKVLFTCFKRNDKREVKGAQLAGSVAEMSSYHHGEASLMMTIINLAQNFVGSNNLNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPVDDNVLRFLYDDNQRVEPEWYMPIIPMVLINGAEGIGTGWSCKIPNFDIRETVNNIRCLLDGKEPLPMLPSYKNFKGTIDELGPNQYVISGEVSILDSTTIEITELPVRTWTQTYKEQVLEPMLNGTEKTPPLITDYKEYHTDTTVKFVVKMSEEKLAEAEAVGLHKVFKLQTNLTCNSMVLFDHVGFLKKYESPQDILKEFFELRLRYYGLRKEWLIGMLGAESAKLNNQARFILEKIDGKIVIENKPKKELIQVLIQRGYESDPVKAWKELQNKEEEEGDESGEESAAATGPDFNYLLNMPLWYLTKEKKDELCKQRDNKDKELEDLKHKSPSDLWKEDLAAFVEELDAVEAKQMQDEMAGITGKPLKVKGGKQGGKQKVTKAQLAEVMPSPHGIRVVPRVTAEMKAEAEKRIKKKIKSEKNESDEKQEGNSSGDKEPSSLKQRLAQKRKAEQGTKRQTTLPFKPIKKMKRNPWSDSESDSESDDFEVPSKRERVVRQAAAKIKPMVNSDSDADLTSSDEDSEYQENSEGNTDSDTTSKKKPPKAKAVPKEKKGKAPKEKPLPDAVPVRVQNVAAESASQDPAAPPVSVPRAQAVPKKPAAAKKGSTAKDNQPSIMDILTKKKAAPKAPRRAQREESPPSEATAAVAKKPGPPRGRKATKRLTSSSDSDSDFGSRPSKSVAAKKSKRDDDDSYSIDLTADSPAAAAPRTRPGRLKKPVQYLESSDEDDMF
What is the function of this protein?
Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand (By similarity).  May play a role in the regulation of circadian rhythm (By similarity).
What are the official names of this protein?
DNA topoisomerase 2-alpha, DNA topoisomerase II, alpha isozyme.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleoplasm. Nucleus. Nucleus, nucleolus.
Protein: CRR18_ARATH
Sequence: MYSSSSVSKRFVLVPIVVVVTTQLLLVRNVSSLNLTNSYLHHKCVVNQGKYKPGSKYEKSLDDIIQSFSNKDKDSYGFRTGYSMKAYGKEPDMVSITYQCRIDSRGPKCQSCVVTAGYELLRKRCPRYKEAIIWYDQCLVEFSSLDTSGQINYDDNFCMPSAKNLIGNSISLEERLHLLNNLTKIAVTKIDKNIEGIKKPVLYAAGEKRLGTKSLYGMVQCSADLSVQGCNECMLYYIVHFQECWENKQGVRVLSRSCNFRYELYPFINPKGPYYTKF
What are the official names of this protein?
Cysteine-rich repeat secretory protein 18.
What is the protein family that this protein belongs to?
Belongs to the cysteine-rich repeat secretory protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: TBB2_SUIBO
Sequence: MSREIVNIQAGQAGNQVGEAFWRMLLAEHGLDDAGMYKGNDPQQIARAGVYFTQVDSSGPTKYVPRSVQVDLESGVCNRLRSGPLGQLFRPDTYFTSDSGAGNNWAKGYYTEGAELIDGILDIVRRQCEATEALQGFQMIHSLGGGTGAGLGSLLLSKLREEYPDRMLSTFSILPAPNVSETVVEPYNSLLSIHQLVDNCDLTICIDNEALYDIAVRTLKIKSPGYKDLNQLIAKVMCGVSTSLRFPGQLNGDLRKLGMNLVPFPRLHFLMPSFAPFYDPKARTFQRLSVSELTSSLFDKKNLLVASDPRFGRYLTAACIFRGKVSSHEAENSVMQLQRKNSNLFVEWIPDNVSVSLCSVPPVGQPQAAVALANSTCMQELFKRNLDQFALMFKRRAFLHWYTGEGMDVMEFTEAESNTQDLISEYQQYQEATVEEEEADIEGEQ
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta-2 chain, Beta-2-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: DTD_NATTJ
Sequence: MRAVVQRVSKSYVNVNGEKVGEINQGLNVLLGVEDGDGEDDIKYLVDKIVNLRIFEDDQGKMNLSVNDIGGELLVISQFTLLGDCRKGRRPNFMKAASPEIADELYQKFVEKVSKDYGLSLATGSFKEHMEVDILNDGPVTILLDSNKKF
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRE_CLOPS
Sequence: MKNTDAMVIDTLKEVGALLEGHFLLSSGRHSNRYCQCAQLLKYPEKAEKVLKVVADQLKDIDFDLVVGPAMGGVIVAYELGRQLGKPAIFTERENGEMTLRRGFTIEKGQKVVITEDVVTTGKSFKEAAKVIEEQGGEVVAVVCIVDRTPGNVTDFPMYSSIKLDIESFEAENCPLCKEGVPYIKPGSRNIK
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: URED_SYNSC
Sequence: MQRLDPWHGRCDLQFHATNGSTKHQGGCTAPFKLLRSERGEDGRCELPVLHTAGGLVGGDQLSLDFKLEANSRGLITSVAAQKVYGSIGRSRLQPEGCFAHQQVRCSLASGSDLEWLPQELVLYADALFEQQLTVTLPQDASFLSAEIVRLGRTAAGETLQQGRWRSSLTIQRLAGESSTWELADRVELGGASLESPHGLGGAPVFGTLVWAAPMAMGAETTASVLEGARADREGLTGTMRCGALNQGLIARYSGESSRDARFWFSRIWERTRTIRGLTRPRIPRVWPLQEQPLRRQTSTVNAFEAAAETH
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_CORJK
Sequence: MKRTNMKKARMEQSRRPKKNPLKAEGIETVDYKNYDLLRKFISERGKIRSRRVTGLTPQQQRQVATAVKNAREMALLPFHSR
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.