PharMolix/UniProtQA huggingface dataset:
Protein: RPOC1_AETCO
Sequence: MIDRYKHQQLRIGSVSPQQISAWATKIIPNGEIVGEVTKPYTFHYKTNKPEKDGLFCERIFGPIKSGICACGNYRVIGDEKEDPKFCEQCGVEFVGSRIRRYQMGYIKLTCPVTHVWYLKRLPSYIANLLDKPLKELEGLVYCDFSFARPITKKPTFLRLRGSFEYEIQSWKYSIPLFFTTQGFDIFRNREISTGAGAIREQLADLDLRIIIENSLVEWKQLGEEGPTGNEWEDRKIVRRKDFLVRRMELAKHFIRTNIEPEWMVLCLLPVLPPELRPIIQIEGGKLMSSDINELYRRVIYRNNTLTDLLTTSRSTPGELVMCQEKLVQEAVDTLLDNGIRGQPMRDGHNKVYKSFSDVIEGKEGRFRETLLGKRVDYSGRSVIVVGPSLSLHRCGLPREIAIELFQTFVIRGLIRQHLASNIGVAKSQIRENKPIVWEILQEVMQGHPVLLNRAPTLHRLGIQSFQPILVEGRTICLHPLVCKGFNADFDGDQMAVHVPLSLEAQAEARLLMFSHMNLLSPAIGDPISVPTQDMLIGLYVLTSGTRRGICANRYNPCNRKNYQNERIYETNYKYMKEPFFCNSYDAIGAYRQKRINLDSPLWLRWQLDQRVSASREVPIEVHYESFGTYHEIYAHYLIVRSIKKETFCVYIRTTVGHISFYREIEEAIQGFSQACSYDT
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', PEP, Plastid-encoded RNA polymerase subunit beta', RNA polymerase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CSST3_CONMK
Sequence: MQTAYWVMVMMMVWITAPLSEGGKLNDVIRGLVPDDVTPKRILQSLISRRRFDGRALFVPSCIWKTCPYG
What is the function of this protein?
Moderately activates human somatostatin receptors (SSTR) with a preferential activation of SSTR1 and SSTR4.  In vivo, does not cause behavioral changes in mice within a few minutes of intracranial injection, but causes a progressive loss of movement thereafter.  Four to five hours after injection, mice recover, even with the highest dose tested.  Shows antinociception and antihyperalgesia activities in two mouse models of acute pain, most probably by acting outside the central nervous system.
What are the official names of this protein?
Consomatin Mrc3, ConSST Mrc3, Somatostatin-related peptide, SSRP.
What is the protein family that this protein belongs to?
Belongs to the conotoxin C superfamily. Consomatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: NAT10_DICDI
Sequence: MVRKKVDTRIRTLIENGVATNHRSFFVIVGDNGKDQVPNLHYILSKSIVKARPSVLWCYKEDLGFSKHKKKKMKLKEKSKSSGIDSVNQEDPFDVFISTTNIRYSYYSESHKILGNTFGMLVLQDFEAITPNLLARTIETVEGGGLIVLLLKTMDSLKQLYTMTMDVHTRFRSENSKGEVVCRFNERFLLSLGKSEQCLVMDDELNILPISSQSRSIEAKQQILETPEQVELREFKQQVKDTDIAGALIENTKTMDQATALLTFIDSISEKTLRSTVTLTAGRGRGKSAALGLAISAAVAFGYSNIFVSSPTPENLNTLFQFVFKGFDSMEYVEHVDYELVKSTNPEFHDAIIRVNIFRSHRQTIQYIQPQDYQKLGQAELVVIDEAAAIPLPLVKNLLGPYLVFMSSTINGYEGTGRSLSLKLIKQLREQSTVVSNSSNKALNSITGRMLREIELNEPIRYSARDPIERWLNELLCLDSTIAKSSPTGCPHPSACQLYYVNRDTLFSYHKASEAFLQKMVGLFVSSHYKNSPNDLLLMSDAPDHHLFVLLGPIDENNTTGLPEILCAVQVSLEGEIAKESILNSIKRGYQASGDLIPWTLTQQYQDEDFPRLSGVRIVRIATHPDYQKMGYGSKALELLTQYYQGEITNLDEVNQEEEEEDEEKVDQNKGSSKISTVKKDNASLLTEVIRPKSNIPPLLFKLSERKPEKLHYMGVSYGLTQQLYQFWSKSKYLPVYLRLTSNDITGEHTCIMLRELNNEQNNTICKDGWLQSFHQDFKKRFINLLGYEFRNFNSSIALNILYEKKVNNTVAVASSTTKNELTQNEMELLFSSYDLKRLESYSNNIVDYHVVIDLLPSLSKLYFTNKLKIEDISLIQSAILLALGLQHKTVDNLIGELNLASNQVLSLFNQTMRKINTELKQKQEKFIQDSMPKLSIVAPRTGQFKSFKGDIKETDMIPLAEDMESELEKGAEEVVNKLKHQLENDSSLSKYLVKGNDEDWSKALKPGSIPNSITIKRKSDENEETDKKENNKKSKTKNNNNNNNNNKKVNNQKSKK
What is the function of this protein?
RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs.  Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA.  Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis.  Catalyzes the formation of ac4C in serine and leucine tRNAs.  Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (By similarity).
What are the official names of this protein?
RNA cytidine acetyltransferase, 18S rRNA cytosine acetyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: XPT_CLOTE
Sequence: MNILKDKINKEGIVIDNRILRVDMFLNHQLDIELLNEIGKEFKNRFKDKEINKILTVETSGIGIACVVAQYFNNVPVVFAKKHAGSNMGENVYESKVYSFTKDIEYTIKVSKDYIDKEDNILIIDDFLASGSAMSGLIDIAEKSGAIVEGVGIVIEKEFQKGRKIILNKGIQLESLAIIKGFEDNKVVFK
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHAAB_ALKCK
Sequence: MGEYRLAVDIGASSGRVMAGKISEAGIDLQEVYRFDNQAQLMGGHYCWDVDHLFGEIKKGIRVAVQSGLQPVSIGMNTWAVDFVLLDEKGERLTDAISYRDPRTNGVMEGVIETYGKKALYERTGIAFQPFNTLYQLLALKKQNPELLEQAHAFLMVPDYFHFLLTGVKVNEYTNATTTQLVNVHTKDWDRQLLKEFGLPCGMFQPLQHPGTKIGSLTESMEKELGVQLEVIVPATHDTASAIAALPEKQTSVYISSGTWSLIGIENRTPICSQQAMAANFTNEGGVGSRIRFLKNIMGLWMIQEVQRLLPGHWSFSQLAQAASESTYTGEIDVDQHRFLKPENMIEEIQQACREKGLAVPESPGDLAKCIYDSLIASYDKAVTEIEAISGKPYEQIHIIGGGALNKEINQRLANRTNKTVIAGPTEATAVGNLLVQAIADGELSRIEEGRALVRTAFPVTYFLPQRSESHVSSRFESAKVQYEQLGIDVEAAFAKVKQVPISVHCWQGDDLHGTEVIANELSGGIDVTGNHPGRARNGEELRRDLEKALSLIPGKHRVNLHAMYAETDSVPIERDQLKTEHFEKWVKWAKSLGIGLDFNPTVFSHPKAADGLTLAHPDEEIRTFWINHCKACRKIAAYFGEQLGTPSLVNIWVPDGYKDTPSDRLTPRKRLKESLDAIYADEYDPMLVLDTVESKLFGIGSEAYVVGSHEFYLNYANQNNKLYLLDTGHFHPTEVVSNKLSAMLLFHDQLALHVSRPVRWDSDHVVTFDDELREIAIELVRNDALGNIHIGLDFFDASINRVAAWAIGTRNMAKALLYAALMPHRHLKQLQDEGDFTSRLAMQEQLKTYPFGDMWDEYCKRQGVPTETEWLDVVKEYEQQVQLKRESEKAKQR
What are the official names of this protein?
Bifunctional enzyme RhaA/RhaB.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the rhamnose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_THISH
Sequence: MRILGIETSCDETGVAVIDAERGLLSHALYSQVALHAEYGGVVPELASRDHIRKLLPLVRQALDGADTAASDLTGIAYTSGPGLLGALLVGAGVARSLAWAWGLPAVGVHHMEGHLLAPLLGDEPPEFPFLALLVSGGHTMLVDVQGVGRYRILGESLDDAAGEAFDKTAKLLGLSYPGGPALAALAERGDPARFSFPRPMTDRPGLDFSFSGLKTRALTTLRETRTEQDRADVARAFEEAVVDTLVIKCLRAVQETGAERLVVAGGVGANRRLRQRLKEAVGAEGASVHYPPFEFCTDNGAMIALAGLMRFQAGAGEDLTIRARARWNLESKSEV
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNME_SHEB9
Sequence: MTTDTIVAQATAPGRGGVGIIRISGDKASDVAMAVLGHLPKTRYADYCDFKSASGQVIDQGIALFFKGPNSFTGEDVLELQGHGGQIVLDMLIKRVMEVGGIRIAKPGEFSEQAFMNDKLDLTQAEAIADLIDATSEQAAKSALQSLQGEFSKEVHELVDQVTNLRLYVEAAIDFPDEEVDFLSDGKIANALYKIIDKLDLVQASAKQGSIIREGMKVVIAGRPNAGKSSLLNALAGKESAIVTEIAGTTRDVLREHIHLDGMPLHIIDTAGLRDTNDTVEQIGIERAWNEINSADRVLFMVDGTTTAAVDPHTIWPDFVDRLPSNLGVTVIRNKADLTGEDLMMTEEQGYSVYRISAKTGLGVEELKQHLKSLMGYQSNLEGGFIARRRHLEALELAAGHLQLGKEQLEVYLAGELLAEELRMCQLALSEITGRFTSDDLLGKIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GA45A_HUMAN
Sequence: MTLEEFSAGEQKTERMDKVGDALEEVLSKALSQRTITVGVYEAAKLLNVDPDNVVLCLLAADEDDDRDVALQIHFTLIQAFCCENDINILRVSNPGRLAELLLLETDAGPAASEGAEQPPDLHCVLVTNPHSSQWKDPALSQLICFCRESRYMDQWVPVINLPER
What is the function of this protein?
In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity (By similarity).  Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase.
What are the official names of this protein?
Growth arrest and DNA damage-inducible protein GADD45 alpha, DNA damage-inducible transcript 1 protein, DDIT-1.
What is the protein family that this protein belongs to?
Belongs to the GADD45 family.
Protein: UREG_RHOPT
Sequence: MSDHHGPLRVGIGGPVGSGKTALMDLLCKSMRERYDIAAITNDIYTKWDAEFLVRSGSLTPDRIAGVETGGCPHTAIREDASMNLAAVAEMRSKFPGLDLVLIESGGDNLAATFSPELADITIYVIDVAAGDKIPSKGGPGITRSDLLVINKIDLAPYVGASLEKMDTDAKRMRGARPFVMTNLKKSEGLDRIIGFIEEKGGLTPRRSA
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPG_YERPS
Sequence: MTRVIVISNLRLAQAFVDYMATHHVALEIRPDAQGVEIWLADDEQLSAVQHELEQFLLDPLNPRYQAASWQAGNVNSNLPYQRFSYLQTLRSQAGPLTLSVMVLCIAIYILMLITGDMAVMSWLAWPYNSSQYLQIWRWVSHAFLHFSLLHILFNLMWWWYLGGQMEKRLGTSKLLVLTIVSAVFSGWGQSLFSGANFGGLSGVVYALMGYVWLTGERAPEHGISLPRGLMAFSVLWLIAGYFDILGLSIANAAHVSGLIIGLLMAFWDTRNSARTVQ
What is the function of this protein?
Rhomboid-type serine protease that catalyzes intramembrane proteolysis.
What are the official names of this protein?
Rhomboid protease GlpG, Intramembrane serine protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KEI1_YEAST
Sequence: MRSSLLTLPKSFLGFMPLYLAVEIVLGISILNKCSGAYGILALFTGHPLDFMQWIAYLWSVFTLIVFSQGLYLIHKPNLLVFSQICVLYTIDTISTCFFTLWFTTQWFTLEDTANIDGNNALQSNPISTGKLTERGIDISKQSATESYEYTMTILITLVSLIFRFYFNFILASFVQELLHHPKYLVDRDDVEQNLKNKPIWKRLWAKSQKGCYKLCKNLLE
What is the function of this protein?
Regulatory component of the inositol phosphorylceramide (ICP) synthase which catalyzes the addition of a phosphorylinositol group onto ceramide to form inositol phosphorylceramide, an essential step in sphingolipid biosynthesis.  Helps the medial Golgi localization of IPC synthase in a COPI vesicle-dependent manner.
What are the official names of this protein?
Inositol phosphorylceramide synthase regulatory subunit KEI1, ICP synthase regulatory subunit KEI1, KEX2-cleavable protein essential for inositol phosphorylceramide synthesis.
What is the protein family that this protein belongs to?
Belongs to the KEI1 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: THIE_DECAR
Sequence: MATNKLRGLYAITPDRADGARLLADVEAALAGGCRVVQYRDKLSTMPEQVARAQALRELTRRFAATLLINDDLALAALVQADGVHLGKDDGNLVVARAILGPDKILGASCYADFAAAEAASRAGADYVAFGAVYPSPTKPQAANATTELFVRAKAELPAATCAIGGITLDNAPPLIVAGADLLAVITDLFSAPDIMARAAAYQRLFEEAHS
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: RF1_KLEP7
Sequence: MKSSIVAKLEALYERHEEVQALLGDAATIADQDKFRALSREYAQLSDVARCYTDWRQVQEDIETAQMMLDDPEMREMAQEELRDAKEKGDQLEQQLQVLLLPKDPDDERNAFVEVRAGTGGDEAALFAGDLFRMYTRYAESRRWQVEILSANEGEHGGFKEVIAKISGDGVYGRLKFESGGHRVQRVPATESQGRIHTSACTVAVMPELPEAEMPDINPADLRIDTFRSSGAGGQHVNTTDSAIRITHLPTGIVVECQDERSQHKNKAKALSVLGARIRAAEVAKRQQAEASTRRNLLGSGDRSDRNRTYNFPQGRVTDHRINLTLYRLDEAMEGKLDMLIEPIVQEHQADQLAALSEQE
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PKN1_CORGL
Sequence: MTFVIADRYELDAVIGSGGMSEVFAATDTLIGREVAVKMLRIDLAKDPNFRERFRREAQNSGRLSHSSIVAVFDTGEVDKDGTSVPYIVMERVQGRNLREVVTEDGVFTPVEAANILIPVCEALQASHDAGIIHRDVKPANIMITNTGGVKVMDFGIARAVNDSTSAMTQTSAVIGTAQYLSPEQARGKPADARSDIYATGCVMYELVTGKPPFEGESPFAVAYQHVQEDPTPPSDFIADLTPTSAVNVDAVVLTAMAKHPADRYQTASEMAADLGRLSRNAVSHAARAHVETEETPEEPETRFSTRTSTQVAPAAGVAAASTGSGSSSRKRGSRGLTALAIVLSLGVVGVAGAFTYDYFANSSSTATSAIPNVEGLPQQEALTELQAAGFVVNIVEEASADVAEGLVIRANPSVGSEIRQGATVTITVSTGREMINIPDVSGMTLEDAARALEDVGLILNQNVREETSDDVESGLVIDQNPEAGQEVVVGSSVSLTMSSGTESIRVPNLTGMNWSQAEQNLISMGFNPTASYLDSSEPEGEVLSVSSQGTELPKGSSITVEVSNGMLIQAPDLARMSTEQAISALRAAGWTAPDQSLIVGDPIHTAALVDQNKIGFQSPTPATLFRKDAQVQVRLFEFDLAALVQ
What are the official names of this protein?
Probable serine/threonine-protein kinase PknB.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: SPED_ECOHS
Sequence: MKKLKLHGFNNLTKSLSFCIYDICYAKTAEERDGYIAYIDELYNANRLTEILSETCSIIGANILNIARQDYEPQGASVTILVSEEPVDPKLIDKTEHPGPLPETVVAHLDKSHICVHTYPESHPEGGLCTFRADIEVSTCGVISPLKALNYLIHQLESDIVTIDYRVRGFTRDINGMKHFIDHEINSIQNFMSDDMKALYDMVDVNVYQENIFHTKMLLKEFDLKHYMFHTKPEDLTDSERQEITAALWKEMREIYYGRNMPAV
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
Protein: HIS6_MYCUA
Sequence: MYTDTGLAVRVIPCLDIDAGRVVKGVNFENLRDAGDPVELAAAYDAEGADELTFLDVTASSSGRATMLEVVRHTAEQVFIPLTVGGGVRTVADVDLLLRAGADKVSVNTAAIARPDLLADMATQFGSQCIVLSVDARKVPVGSSPTPSGWEVTTHGGRRGTGIDAVEWAARGADLGVGEILLNSMDADGTKAGFDLAMLRAVRAAVTVPVIASGGAGNVDHFAPAVAAGADAVLAASVFHFRELTIGQVKAAMAAEGNTVR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROB_ECOL6
Sequence: MERIVVTLGERSYPITIASGLFNEPASFLPLKSGEQVMLVTNETLAPLYLDKVRGVLEQAGVNVDSVILPDGEQYKSLAVLDTVFTALLQKPHGRDTTLVALGGGVVGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVVDLDCLKTLPPRELASGLAEVIKYGIILDGAFFNWLEENLDALLRLDGPAMAYCIRRCCELKAEVVAADERETGLRALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAARTSERLGQFSSAETQRIITLLTRAGLPVNGPREMSAQAYLPHMLRDKKVLAGEMRLILPLAIGKSEVRSGVSHELVLNAIADCQSA
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HFQ_XYLFT
Sequence: MAKGQSLQDPFLNALRRERVPVSVYLVNGIKLQGTIESFDQFVVLLRNTVSQMVYKHAISTVVPARNVRVGPGGGYVHSGSDTLQINDDEVE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: RLF_ARATH
Sequence: MDTSRDDDFTFSKVSPPDSEVKDLASDVGSITLKDGLDQQKSNGLIWKDKSLPPKEETIGSLSFTVTDSSSSKKQSNESSETFKTPARKPITRTKVPFEKGYSQMDWLKLTRTHPDLAGLKGESNKRLIPMDEVKKHRTGDSMWTVLKGRVYNISPYMNFHPGGVDMLMKAVGRDGTLLFNKYHAWVNVDILLEKCLVGVLDDTKVKKQEP
What is the function of this protein?
Involved in the control of lateral root (LR) formation.  Acts a positive regulator of early cell divisions involved in LR initiation, independently of ARF7 and ARF19-mediated auxin signaling.
What are the official names of this protein?
Cytochrome b5 domain-containing protein RLF, Protein REDUCED LATERAL ROOT FORMATION.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b5 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: SCTR_HUMAN
Sequence: MRPHLSPPLQQLLLPVLLACAAHSTGALPRLCDVLQVLWEEQDQCLQELSREQTGDLGTEQPVPGCEGMWDNISCWPSSVPGRMVEVECPRFLRMLTSRNGSLFRNCTQDGWSETFPRPNLACGVNVNDSSNEKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMHLFVSFILRALSNFIKDAVLFSSDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLLVEGLYLHTLLAISFFSERKYLQGFVAFGWGSPAIFVALWAIARHFLEDVGCWDINANASIWWIIRGPVILSILINFILFINILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHYIVFAFSPEDAMEIQLFFELALGSFQGLVVAVLYCFLNGEVQLEVQKKWQQWHLREFPLHPVASFSNSTKASHLEQSQGTCRTSII
What is the function of this protein?
Receptor for secretin (SCT), which is involved in different processes such as regulation of the pH of the duodenal content, food intake and water homeostasis (PubMed:7612008, PubMed:25332973).  The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity).  Upon binding to secretin, regulates the pH of the duodenum by (1) inhibiting the secretion of gastric acid from the parietal cells of the stomach and (2) stimulating the production of bicarbonate (NaHCO(3)) from the ductal cells of the pancreas (By similarity).  In addition to regulating the pH of the duodenal content, plays a central role in diet induced thermogenesis: acts as a non-sympathetic brown fat (BAT) activator mediating prandial thermogenesis, which consequentially induces satiation.  Mechanistically, secretin released by the gut after a meal binds to secretin receptor (SCTR) in brown adipocytes, activating brown fat thermogenesis by stimulating lipolysis, which is sensed in the brain and promotes satiation.  Also able to stimulate lipolysis in white adipocytes.  Also plays an important role in cellular osmoregulation by regulating renal water reabsorption.  Also plays a role in the central nervous system: required for synaptic plasticity (By similarity).
What are the official names of this protein?
Secretin receptor, SCT-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: OYEB_SCHPO
Sequence: MAVQKLYESQSKLFQPIKVGNMQLQHRMVHAPATRLRCLDNGLVMTDLVKEYYKQRSSIPGTLLITESLFSGAKSGGFSNIPCLYNDEHVEAWKPIVQAIHDNDCFVFIQFWNLPGELKVDYLEDQERLEKVTQGECPMDPTGLPAALGSAYSICGEELYVDKFMTKQDIQEHITTYTEAAKRAVFGCGADGVEVHQVNGFLLDKFVLNGYGDKCDPEYCGSLENRARFCLELLESVVNAIGQERVGYRISPFSDIWKDKDSFEAHVFMIKKIKERFPNLAYLHAIEPRQYWNGHVHITQEKNTLIYKNLWGDPFITAGGHDRDSAIQMAEQENTLVAFGRYFLSNPDLPFRLKYNLPLNKWDRATFYTKMSPKGYIDYPFSKEFLDTKKVE
What are the official names of this protein?
Putative NADPH dehydrogenase C5H10.10, Old yellow enzyme homolog 2.
What is the protein family that this protein belongs to?
Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.
Protein: YM084_YEAST
Sequence: MCGIFGYCNFLIEKTRGEIIDTLIEGLQALEYKEYDSSGISIQGDELESLNIYKQTGKISSLKEEIDLYNLNKNLPFISHCGIAHTRRATHGGLRRANCHPHNSDPSNEFVVVHNGVITNFANLKALLMAKGYVFKSDTDTECIPKLYKHIYDTSIELGYNLDFHVLTNLVLKELEGSYGLLCTSSHFPDEVVAARKGSPLVIGVKGKTDMDVNFVEVEYLDQEEDYLKLNTQTKSSGNVLAAAPVKYNTCLRKSPPFVHNT
What is the function of this protein?
Involved in amino sugar synthesis (formation of chitin, supplies the amino sugars of asparagine-linked oligosaccharides of glycoproteins).
What are the official names of this protein?
Putative glutamine--fructose-6-phosphate aminotransferase [isomerizing], GFAT, D-fructose-6-phosphate amidotransferase, Hexosephosphate aminotransferase.
Protein: TERR_ASPTN
Sequence: MFAELNAKDQFNELLKHLSSTSCTTMQADRVETSSSVRKKKWMSRRRGACDMCKSKKVRCDGGTPCSYCNLHDLRCEYQLSKKQQTNKPPVASAAEDVSIVPSYAENNGSGVTTQVPSPSDVQVLPELTANRGSGNAGNILQDMMLATNDRHSMPVMFDGYAHDNFSASPIEWVGSDSLAAPFSVDMGNLNALGTLPWSPPKTAYSEPNLDIPYPIEHTTDVSASLPSISQFELNLPLSPAGPTRDMYDEKMWEEVSPKRQRLGNLSPTQQDEVEAIFRRLSDAQSQMSFGLGGEQYDSHSRWYWSDTALMEKCKSACFEEPLGISTFLTRSHFDDYVQQARESPSIQGLAVRPLIDSVMAFGFHILAARSQPSAGSDVSRKAITRLRMALSSRDAVQRSPDTLLKLQMTISEQIDHKIHTELLSYAVSCARSRRFLHRDSVYMTMTKEKEYLARRSMWYLYSMEVVHSIRDGMPPILTPDWTDYALPEVGKDTDTDWLLIQCQHANALSSAVNALYSPRALCQTVAERERNMMQAHKLLENWRTSLPVHLQNIHRHETGYVALDDQKTRHLTLTMVGKYHEAIFIIFFPWTGSQSKGLISEHYRKRSMELCVKSAQAVLAIAARITSCDILGGSLAS
What is the function of this protein?
Transcription factor that regulates specifically the terrein biosynthesis gene cluster (PubMed:24816227, PubMed:26173180, PubMed:25852654).  Recognizes CGG direct repeat consensus sequences in the terrein cluster forming the high affinity consensus motif TCGGHHWYHCGGH (PubMed:25852654).
What are the official names of this protein?
Terrein cluster-specific transcription factor terR.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL32_STRP7
Sequence: MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSLKGYYKGRKIAKAASAE
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: HMFB_METFE
Sequence: MELPIAPIGRIIKDAGAERVSDDARITLAKILEEMGRDIASEAIKLARHAGRKTIKAEDIELAVRRFKK
What is the function of this protein?
Binds and compacts DNA (95 to 150 base pairs) to form nucleosome-like structures that contain positive DNA supercoils (PubMed:2377617, PubMed:7809089, PubMed:10704305, PubMed:28798133).  Increases the resistance of DNA to thermal denaturation in vitro (PubMed:2377617).
What are the official names of this protein?
DNA-binding protein HMf-2, Archaeal histone B.
What is the protein family that this protein belongs to?
Belongs to the archaeal histone HMF family.
What are the subcellular locations of this protein?
Cytoplasm. Chromosome.
Protein: RL16_PHYAS
Sequence: MLMPKRTKYRRPHRVSFEGKAKGKNVIVNGNYALVAKEGAFITNKQIEACRIAMNRYMKRTGKVWINIFPHLSLTKKPLEVRMGSGKGSPEEWVAVVKTGKVLFEVKDTSNSEKVEMEALRLASHKLPIKTKIVKKGVQV
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.