PharMolix/UniProtQA huggingface dataset:
Protein: OSB10_DICDI
Sequence: MTDISDESNIGYEEEVEEEIMEDDLDINNDGCDGEDKKKNSGFLKQFASKQPFYKMSLPISYSEPRSFLEKLSDQGSFLDILLKVKNIENEDDRFLEILKFYLSGWIQQKIAKSPFNPVIGETYQCKWVHKDGSTTEYIAEQISHHPPSSSFCMHNQQNGVIFHSHLSPTSKFWGNSLENSMEGKLVYEIPSLQEEYIVEAPKIIVKGVLVGSLSTETVGSTNLTCKKTGYSAEIEFKGKGLFKSKHSLLVKVKHPSSKKALYTLEGKFDGTVSITSTKTGKTTAFFDINSDQIQPITSPLHELEENNSRVVWKHVIENLLNNNEDEASKQKTIVEENQRNLAKTREGKPWIPKNFIKVDNDDNEDSANQNNVYYYSKLIEIRKEIMKNN
What are the official names of this protein?
Oxysterol-binding protein 10, OSBPj.
What is the protein family that this protein belongs to?
Belongs to the OSBP family.
Protein: RL39_METS5
Sequence: MSRYKPSGLKKRLNKALKSNSSVPAWVILKTNGEVRFNPKRRNWRRNDLKV
What are the official names of this protein?
50S ribosomal protein L39e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL39 family.
Protein: SYD_PROMH
Sequence: MRTNYCGQLNSAHVGQKVTLCGWVNRRRDLGGLIFIDMRDREGIVQVFFDPEQKEAFSQASELRNEFCIQVTGTVRARPDSQVNKNMATGEIELAAESLSIFNRSEALPLDSNQTNTEERRLTYRYLDLRRPEMSQRLKTRAKITSFVRRFMDGEGFLDVETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDVETSFMTAEQVREVMERMIHALWLDILNVDLGAFPVMTFAEAMRRYGSDKPDLRNPMELIDIADLVKNVEFSVFAQAANDEKCRVIALRVPGGASLTRKNIDEYTQFVSIYGAKGLAWMKVNEKAKGIEGVQSPIAKFLTNDVVNSILAATNATDGDLIFFGAGRQGTMSDAMGALRLKVGRDLELTDLNAWKPLWVIDFPMFEEDEDTGSLSAMHHPFTSPKDLTPAELTAHPVGAVANAYDMVINGYEVGGGSVRIHRNEMQQAVFSILGITPDEQREKFGFLLDALKFGTPPHAGLAFGLDRLVMLLTGTDNIRDVIAFPKTTAAACLMTNAPSFANEDALKELAIQVTEKEVSTDNE
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFGH2_SHISS
Sequence: MEMLEEHRCFEGWQQRWRHDSSTLNCPMTFSIFLPPPRDHTPPPVLYWLSGLTCNDENFTTKAGAQRVAAELGIVLVMPDTSPRGEKVANDDGYDLGQGAGFYLNATQPPWATHYRMYDYLRDELPALVQSQFNVSDRCAISGHSMGGHGALIMALKNPGKYTSVSAFAPIVNPCSVPWGIKAFSTYLGEDKNAWLEWDSCALMYASNAQDAIPTLIDQGDNDQFLADQLQPAVLAEAARQKAWPMTLRIQPGYDHSYYFIASFIEDHLRFHAQYLLK
What is the function of this protein?
Serine hydrolase involved in the detoxification of formaldehyde.  Hydrolyzes S-formylglutathione to glutathione and formate (By similarity).
What are the official names of this protein?
S-formylglutathione hydrolase YeiG, FGH.
What is the protein family that this protein belongs to?
Belongs to the esterase D family.
Protein: RS20_BORAP
Sequence: MRKNASALKRSRQNLKRKIRNVSVKSELKTIEKRCINMIKAGKKDEAIEFFKFVAKKLDTAARKRIIHKNKAARKKSRLNVLLLK
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: ARL3_BOVIN
Sequence: MGLLSILRKLKSAPDQEVRILLLGLDNAGKTTLLKQLASEDISHITPTQGFNIKSVQSQGFKLNVWDIGGQRKIRPYWRNYFENTDILIYVIDSADRKRFEETGQELAELLEEEKLSCVPVLIFANKQDLLTAAPASEIAEGLNLHTIRDRFWQIQSCSALTGEGVQDGMNWVCKNVSAKKK
What is the function of this protein?
Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP).  Required for normal cytokinesis and cilia signaling.  Requires assistance from GTPase-activating proteins (GAPs) like RP2 and PDE6D, in order to cycle between inactive GDP-bound and active GTP-bound forms.  Required for targeting proteins to the cilium, including myristoylated NPHP3 and prenylated INPP5E.  Targets NPHP3 to the ciliary membrane by releasing myristoylated NPHP3 from UNC119B cargo adapter into the cilium (By similarity).  Required for PKD1:PKD2 complex targeting from the trans-Golgi network to the cilium (By similarity).
What are the official names of this protein?
ADP-ribosylation factor-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, spindle. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Cell projection, cilium. Note=Detected predominantly in the photoreceptor connecting cilium. Present on the mitotic spindle. Centrosome- associated throughout the cell cycle. Not detected to interphase microtubules (By similarity).
Protein: FABD_BACSU
Sequence: MSKIAFLFPGQGSQFIGMGKELYEQVPAAKRLFDEADETLETKLSSLIFEGDAEELTLTYNAQPALLTTSIAVLEKFKESGITPDFTAGHSLGEYSALVAAGALSFKDAVYTVRKRGEFMNEAVPAGEGAMAAILGMDAEALKQVTDKVTEEGNLVQLANLNCPGQIVISGTAKGVELASELAKENGAKRAIPLEVSGPFHSELMKPAAEKLKEVLDACDIKDADVPVISNVSADVMTEKADIKEKLIEQLYSPVRFEESINKLIAEGVTTFIEIGPGKVLSGLVKKVNRRLKTIAVSDPETIELAIQTLKEENDNA
What are the official names of this protein?
Malonyl CoA-acyl carrier protein transacylase, MCT.
What is the protein family that this protein belongs to?
Belongs to the FabD family.
Protein: Y495_MYCTO
Sequence: MWRPAQGARWHVPAVLGYGGIPRRASWSNVESVANSRRRPVHPGQEVELDFAREWVEFYDPDNPEHLIAADLTWLLSRWACVFGTPACQGTVAGRPNDGCCSHGAFLSDDDDRTRLADAVHKLTDDDWQFRAKGLRRKGYLELDEHDGQPQHRTRKHKGACIFLNRPGFAGGAGCALHSKALKLGVPPLTMKPDVCWQLPIRRSQEWVTRPDGTEILKTTLTEYDRRGWGSGGADLHWYCTGDPAAHVGTKQVWQSLADELTELLGEKAYGELAAMCKRRSQLGLIAVHPATRAAQ
What are the official names of this protein?
Uncharacterized protein MT0515.
What is the protein family that this protein belongs to?
To M.leprae ML2435 and S.coelicolor SCO3349.
Protein: FABZ_ECOL5
Sequence: MTTNTHTLQIEEILELLPHRFPFLLVDRVLDFEEGRFLRAVKNVSVNEPFFQGHFPGKPIFPGVLILEAMAQATGILAFKSVGKLEPGELYYFAGIDEARFKRPVVPGDQMIMEVTFEKTRRGLTRFKGVALVDGKVVCEATMMCARSREA
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPC4_ARATH
Sequence: MIETTKGGSGSYPIKTIVVLVQENRSFDHTLGWFKELNREIDGVTKSDPKSNTVSSSDTNSLRVVFGDQSQYVNPDPGHSIQDIYEQVFGKPWDSGKPDPNPGHPNMSGFAQNAERNKKGMSSAVMNGFKPNALPVYKELVQNFAICDRWFASVPASTQPNRLYVHSATSHGATSNDKKLLLEGFPQKTIFESLDEAGFSFGIYYQFPPSTLFYRNLRKLKYLTHFHQYGIQFKKDCKEGKLPNYVVVEQRWFDLLSTPANDDHPSHDVSEGQKLVKEVYEALRSSPQWNEILFIITYDEHGGFYDHVPTPVDGVPNPDGILGPPPYNFEFNRLGVRVPTFFISPWIEPGTVIHGPNGPYPRSQYEHSSIPATVKTIFKLKDFLSKRDSWAGTFESVITRDSPRQDCPETLSTPIKLRGTMAKENAQLSEFQEDLVIMAAGLKGDYKNEELIHKLCKETCVADASKYVTNAFEKFLEESRKARDRGCDENDIVYCVDDDDDHVVIPPQSHSEASNAAAQPKTQTSFFNKLFSCFIRHD
What is the function of this protein?
Non-specific phospholipase C (PLC) which assumes major PLC activity during inorganic phosphate starvation.  Substrate preference is phosphatidylcholine (PC), but can also hydrolyze phosphatidylethanolamine (PE) with lower efficiency.  Has no activity toward phosphatidic acid (PA).  Plays an important role in the supply of both inorganic phosphate and diacylglycerol from membrane-localized phospholipids during phosphate deprivation.  May be required for lipid-derived signaling molecules that positively modulate abscisic acid (ABA) response and promote plant tolerance to drought and salt stresses.  May be involved in brassinolide-mediated signaling in root development.
What are the official names of this protein?
Non-specific phospholipase C4.
What is the protein family that this protein belongs to?
Belongs to the bacterial phospholipase C family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SIRJ_LEPMC
Sequence: MKSEPGNEFLERAANLLSRVPLIDGHNDWANIIRGYYSNKIHVRNFSREESLVGHVDIKKLRKGLVGGTFWSAYVDCPAQDKINVFNDDSYLETIRETLQQIDLILRLIKKYPDDLELATTSSGILSSFQNGKIASLLGIEGLHQIGNSPSVLRMFYNLGVRYATLTHNHNNAYADSATAKTPVHNGLSIKGRAIIQEMNRLGMIIDLSHTSEQTAEDVLRQTRAPIIFSHSSAFGVHPHPRNVKDNILHMLKSNKGLIMISFVPEFSSADPGLSSLMDVVKHIIYVGELIGYDHVGIGSDFDGMARAVLGLSDTSTFPRLVAELIANQIPEGDVEKIVGGNLIRVMGDVEAVAHRQCEDDILELEEEVKPLWDDAFKAKIAAAYPEALALNAL
What is the function of this protein?
Dipeptidase; part of the gene cluster that mediates the biosynthesis of sirodesmin PL, an epipolythiodioxopiperazine (ETP) characterized by a disulfide bridged cyclic dipeptide and that acts as a phytotoxin which is involved in the blackleg didease of canola (PubMed:15387811, PubMed:18272357, PubMed:19762440).  SirD catalyzes the O-prenylation of L-tyrosine (L-Tyr) in the presence of dimethylallyl diphosphate (DMAPP) to yield 4-O-dimethylallyl-L-Tyr, and therefore represents probably the first pathway-specific enzyme in the biosynthesis of sirodesmin PL (PubMed:19762440, PubMed:21038099, PubMed:24083562).  4-O-dimethylallyl-L-Tyr, then undergoes condensation with L-Ser in a reaction catalyzed by the non-ribosomal peptide synthase sirP to form the diketopiperazine (DKP) backbone (PubMed:18272357).  Further bishydroxylation of the DKP performed by the cytochrome P450 monooxygenase sirC leads to the production of the intermediate phomamide (PubMed:27390873).  This step is essential to form the reactive thiol group required for toxicity of sirodesmin PL (PubMed:27390873).  The next steps of sirodesmin biosynthesis are not well understood yet, but some predictions could be made from intermediate compounds identification (PubMed:18272357).  Phomamide is converted into phomalizarine via oxidation, probably by sirT (PubMed:18272357).  Further oxidation, methylation (by sirM or sirN) and reduction steps convert phomalizarine to deacetyl sirodesmin (PubMed:18272357).  Finally, acetyltransferase sirH probably acetylates deacetyl sirodesmin to produce sirodesmin PL (PubMed:18272357).
What are the official names of this protein?
Dipeptidase sirJ, Sirodesmin biosynthesis protein J.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
Protein: GLPE_COXBR
Sequence: MMYKQISHLEAWELVKKRDIVIADVRDQDSYEEEHIANALHLSMAKLQEYSEKADKEKPVLVYCYHGISSQSVAQHLVEQGFKEVYSLIGGFETWKAHHPTSDANKN
What is the function of this protein?
Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
What are the official names of this protein?
Thiosulfate sulfurtransferase GlpE.
What is the protein family that this protein belongs to?
Belongs to the GlpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCAP_IHNVO
Sequence: MTSALRETFTGLRDIKGGVLEDAETEYRPGTITLPLFFSKTDFDLEMIKRAVSQVGGEGTRRALGLLCAFVIAETVPSEAGTVAELLEALGFVLESLDTGAPPDATFADPNNKLAETIVKENVLEVVTGLLFTCALLTKYDVDKMATYCQNKLERLATSQGIGELVNFNANRGVLARIGSVLRPGQKLTKAIYGIILINLSDPAIAARAKALCAMRLSGTGMTMVGLFNQAAKNLGALPADLLEDLCMKSVVESARRIVRLMRIVAEAPGVAAKYGIMMSRMLGEGYFKAYGINENARITCILMNINDRYDDGTSRGLTGIKVSDPFRKLAREIARLLVLKYDGDGSTGEGASELIRRAEMASRGPDMGEEEEEDEEDDYSSEPGDSDSFR
What is the function of this protein?
Encapsidates the genome, protecting it from nucleases.  If expressed without protein P it binds non-specifically RNA and therefore can bind it's own mRNA.  Interaction with protein P abolishes any non-specific RNA binding, and prevents phosphorylation.  The soluble N-P complex encapsidates specifically the genomic RNA, with protein N protecting the genome like a pearl necklace.  The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for viral transcription and replication.  Protein N binds protein P in the NC through a different interaction, and can be phosphorylated.  Subsequent viral replication is dependent on intracellular concentration of newly synthesized protein N.  During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).
What are the official names of this protein?
Nucleoprotein, NP, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the novirhabdovirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: RL32_SALTI
Sequence: MAVQQNKPTRSKRGMRRSHDALTAVTSLSVDKTSGEKHLRHHITADGYYRGRKVIAK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: BIOF_TREDE
Sequence: MSNIHDMEFLQKKVQELKEQGLYKELVTLEGPSDAECVINGKKVINLSSNNYLGFANHPRLKKAAIEAIEKYGAGAGAVRPIIGNMKIHDDLEKLLAEFKREEAVLAFQSGFNCNAGVIQALTDKGDLIISDQLNHASIIDGTRLSKADKAVFQHSDMADLERVLKEKRNNYNNVLIITDGVFSMDGDIAKLPEIVALAEKYNCLTYVDDAHSSGVLGESGRGTVDHFKLHGRVDVAMGTLSKAIGVVGGYVAGKKVTIDWLKNRGRPFLFSTGLPPAAVGAAIEAVKMLMESTEYTDKLWANAKHFKEGLGKLGYNIGHSETPITPIIIGDEAKTLEFSKKLFENGLFSGPIVFPTVPKGTGRVRCMVTAGHTTEQLDRAVKICEKVGKEMGII
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase, Alpha-oxoamine synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: LEXA_LISMO
Sequence: MKISKRQQDIYEFIKSEVKEKGYPPSVREIGEAVGLASSSTVHGHLARLEGKGLIRRDPTKPRAIEILSLEDEAETPNVVNIPIIGKVTAGMPITAIENIDEYFPLPEYMAAGETNVFMLEIDGESMINAGILDGDKVIVRQESSAINGEIVVAMTDENEATCKRFYKEANHFRLQPENDALEPILLNNVTILGKVIGLYRDIR
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: WALK_STAAT
Sequence: MKWLKQLQSLHTKLVIVYVLLIIIGMQIIGLYFTNNLEKELLDNFKKNITQYAKQLEISIEKVYDEKGSVNAQKDIQNLLSEYANRQEIGEIRFIDKDQIIIATTKQSNRSLINQKANDSSVQKALSLGQSNDHLILKDYGGGKDRVWVYNIPVKVDKKVIGNIYIESKINDVYNQLNNINQIFIVGTAISLLITVILGFFIARTITKPITDMRNQTVEMSRGNYTQRVKIYGNDEIGELALAFNNLSKRVQEAQANTESEKRRLDSVITHMSDGIIATDRRGRIRIVNDMALKMLGMAKEDIIGYYMLSVLSLEDEFKLEEIQENNDSFLLDLNEEEGLIARVNFSTIVQETGFVTGYIAVLHDVTEQQQVERERREFVANVSHELRTPLTSMNSYIEALEEGAWKDEELAPQFLSVTREETERMIRLVNDLLQLSKMDNESDQINKEIIDFNMFINKIINRHEMSAKDTTFIRDIPKKTIFTEFDPDKMTQVFDNVITNAMKYSRGDKRVEFHVKQNPLYNRMTIRIKDNGIGIPINKVDKIFDRFYRVDKARTRKMGGTGLGLAISKEIVEAHNGRIWANSVEGQGTSIFITLPCEVIEDGDWDE
What is the function of this protein?
Member of the two-component regulatory system WalK/WalR that regulates genes involved in cell wall metabolism, virulence regulation, biofilm production, oxidative stress resistance and antibiotic resistance via direct or indirect regulation of autolysins.  Functions as a sensor protein kinase which is autophosphorylated at a histidine residue in the dimerization domain and transfers its phosphate group to the conserved aspartic acid residue in the regulatory domain of WalR.  In turn, WalR binds to the upstream promoter regions of the target genes to positively and negatively regulate their expression.
What are the official names of this protein?
Sensor protein kinase WalK.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TDH_SALTI
Sequence: MKALSKLKAEEGIWMTDVPEPEVGHNDLLIKIRKTAICGTDVHIYNWDEWSQKTIPVPMVVGHEYVGEVVGIGQEVKGFKIGDRVSGEGHITCGHCRNCRGGRTHLCRNTTGVGVNRPGCFAEYLVIPAFNAFKIPDNISDDLASIFDPFGNAVHTALSFDLVGEDVLVSGAGPIGVMAAAVAKHVGARHVVITDVNEYRLELARKMGVTRAVNVAKESLNDVMAELGMTEGFDVGLEMSGAPPAFRTMLDTMNHGGRIAMLGIPPSDMSIDWTKVIFKGLFIKGIYGREMFETWYKMAALIQSGLDLSPIITHRFSVDDFQKGFDAMCSGQSGKVILSWD
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_KLULA
Sequence: MAPSTKATAAKKAVVKGTNGKKALKVRTSASFRLPKTLKLARSPKYATKAVPHYNRLDSYKVIEQPITSETAMKKVEDGNTLVFKVSLKANKYQIKKAVKELYEVDVLSVNTLVRPNGTKKAYVRLTADFDALDIANRIGYI
What are the official names of this protein?
60S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: ILVC_PHOLL
Sequence: MANYFNTLNLRQQLAQLGKCRFMAREEFVDETGYLKGKKVVIVGCGAQGLNQGLNMRDSGLDIAYALRKEAIEEKRASWRKATENGFQVGTYEELIPQADLVINLTPDKQHSSVVSAVQPLMKEGAALGYSHGLNIVEVGEQIRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGAHRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCYDKLVADGAEPGYAGKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEMMTPLFQKHMDDIISGEFSSGMMADWANDDKKLLGWREETGNTSFENSPEYDGKISEQEYFDHGVLMVAMVKAGVELAFEIMVDTGIIAESAYYESLHELPLIANTISRKRLYEMNVVISDTAEYGNYLFSHVAVPLLKEKFMGSLQAGDLGKPVVDNGIDNAQLRDVNEAIRHHPIEVVGRVLRGYMTDMKRIAVGG
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: NUOH_CUTAK
Sequence: MSPLEATIDPVWLIIVKVVILFVILLAWTIFNVWFERRVLAKMQNRIGPIMNSAWAGGVFQAVGDGLKLIFKEMLTPKGADKIVFNLAPVIAGIACFASWSVIPLGGQVSMFGHTTRLQITDVPVAVLFILAVASIGIYGVVLAGWSSAGTYSLLGSLRSSAQMISYEVAMGLSLVTVFIFSGSMSTSQIVESQANHLVVGGFDTHIAGHYWLLLIPSFVIYVITMFGESNRLPFDLPECESELVSGYITEYSGFPYGMYFLAEYINMATLSAVCTTLFLGGYRAPWPLNYFGVIDSGWWGLLWFFLKTQLVIFFFVWVRAAIPRFRYDHFMDLGWKVLIPVSLGWVLLVAAWRTVINQGWGRNPVFLVVVGVILVALIVWAFMGGKTDSTADEAPDEPFDAFAGGYPVPPLPHQVQAPLAGAATATTVARRDHDENGGL
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RISB_CLOPE
Sequence: MRILEGNLIGQDKKFAIVAGRFNEFIVSKLIGGALDAFKRHGVEEENIDLAWVPGAFEIPLIAKKLAKSGKYAGVVCLGTVIRGATSHYDYVCGEVSKGIANVSLDTEVPVIFGIVTTENIEQAIERAGTKAGNKGFDAAMAAIEMANLLENI
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: TARA_STAAU
Sequence: MTVEERSNTAKVDILGVDFDNTTMLQMVENIKTFFANQSTNNLFIVTANPEIVNYATTHQAYLELINQASYIVADGTGVVKASHRLKQPLAHRIPGIELMDECLKIAHVNHQKVFLLGATNEVVEAAQYALQQRYPNISFAHHHGYIDLEDETVVKRIKLFKPDYIFVGMGFPKQEEWIMTHENQFESTVMMGVGGSLEVFAGAKKRAPYIFRKLNIEWIYRALIDWKRIGRLKSIPIFMYKIAKAKRKIKKAK
What is the function of this protein?
Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.
What are the official names of this protein?
N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase, N-acetylmannosaminyltransferase, UDP-N-acetylmannosamine transferase, UDP-N-acetylmannosamine:N-acetylglucosaminyl pyrophosphorylundecaprenol N-acetylmannosaminyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
Protein: KEFF_ECO55
Sequence: MILIIYAHPYPHHSHANKRMLEQARTLEGVEIRSLYQLYPDFNIDIAAEQEALSRADLIVWQHPMQWYSIPPLLKLWIDKVFSHGWAYGHGGTALHGKHLLWAVTTGGGESHFEIGAHPGFDVLSQPLQATAIYCGLNWLPPFAMHCTFICDDETLEGQARHYKQRLLEWQEAHHG
What is the function of this protein?
Regulatory subunit of a potassium efflux system that confers protection against electrophiles.  Required for full activity of KefC.  Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system ancillary protein KefF, Quinone oxidoreductase KefF.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SYL_BURVG
Sequence: MHERYVPADVEAAAQGDWRAADAYKTKEDSQKPKFYCVSMLPYPSGKLHMGHVRNYTINDVMYRYLRMNGYNTLMPMGWDAFGMPAENAAMANGVPPAKWTYDNIDYMKGQMQSMGLAIDWSREIATCKPDYYKWNQWLFLKMLEKGIAYKKTGTVNWDPVDQTVLANEQVIDGRGWRSGALVEKREIPMYYLRITQYADELLNDLDGLGWPERVKIMQQNWIGKSFGVNFGFPYELDGEKALLRVFTTRADTIMGVTFCAIAAEHPLATRLAQGKPELQAFIDECKRGGVAEADVATMEKKGIATGFSVTHPLTGEAVEVWIGNYVLMSYGEGAVMGVPGHDERDFAFAKKYGLPIKQVIAAEGQTYSLDAWQEWYGDKDAAVCVNSGKYDGLRYTEAVDAVAADLKAGGFGDKQVTWRLRDWGVSRQRYWGTPIPIIHCPSCGDVPVPEQDLPVVLPEDLVPDGTGNPLAKSEAFLNCTCPKCGAAAKRETDTMDTFVDSSWYFSRYTAPDADTMVDARTDYWMPMDQYIGGIEHAILHLLYSRFWTKVMRDLGLVKFGEPAKNLLTQGMVLNETYYREDATGKKTWYNPADVTVTHDDKGRPVGATLNADGQPVVLGGIEKMSKSKNNGVDPQVLIDQYGADTARLFTMFAAPPEQQLEWSGAGVEGASRFLRRVWSFGAGNREALAARAGFDAASLGDADKALRREIYSVLKQADFDYQRLQYNTVVSAAMKMLNAIDGAKGATPGVLRETYGVLLRVLYPVVPHVTFELWKALGYADEFGPLLDAPWPKVDEAALEQAEIELVLQVNGKVRGALKVAKDATREAIEVAAVADEAFAKFSDGKPAKKIVVVPGRLVNIVV
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.