PharMolix/UniProtQA huggingface dataset:
Protein: EIF3J_EMENI
Sequence: MPPSKWDEEEEEGVSPPPVAARRRFDDEEDGDVLDSWDAADDSEVEREKAAKAAEAKAKAEAEAAANKKSKAQRIAEHKTRRKAAEDEEDDESDEDEAEKRARLRRTEKDSDLKHAEDLFGDIDLNRNRGKNKTIVVHDASGDPTQAVDLSAMPLFKPATKEQFTTLSNTLVPLLTAQSKKPQYALWLPEFAKQLAKELPSGDIKKVASALTTLSNEKMKEERAADKGSKKTKAAKTKVSLVASRSDKIETTAYDDDGLDDDDFM
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit J, eIF3j, Eukaryotic translation initiation factor 3 30 kDa subunit, eIF-3 30 kDa.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit J family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RFX1_MOUSE
Sequence: MATQSYVTELQAAPQASQPPQAPPQALPQPPPPAAPQPPAAATPQPQYVTELQSPQPQTQPPGSQKQYVAELPAAPAPSQPATPAPSPVAQQYIVVTVSEGAMRASETVSEASPSSTASQTGVPTQVVQQVQGTQQRLLVQASVQAKPGHVSPLQLTNIQVPQQAIPTQHLVVQSPAPGTKSGQVSLTVHSAQQVHSAPERSPVQANNSTSKTAGTPAATVQQLQVHSVQQSVPVTQERSVVQATPQTKAGPVQQLTVQGLQPVHVAQEVQQLPQVPVPHVYSSQVQYVEGGDASYTASAIRSSTYQYPETPIYTQTAGTSYYEASGTAAQVSTPATSQTVASSGSVPMYVSGSPIVASSSSSEAGASNSSVGAGGNGGGGSSGGGSGGSSGSGAGTYVIQGGYMLGNASQSYSHTTRASPATVQWLLDNYETAEGVSLPRSTLYCHYLLHCQEQKLEPVNAASFGKLIRSVFMGLRTRRLGTRGNSKYHYYGLRIKASSPLLRLMEDQQHMAMRGQPFSQKQRLKPIQKMEGVANGVAVGQQSTGLSDISAQVQQYQQFLDASRSLPDFAELDLQGKVLPEGVGPGDIKAFQVLYREHCEAIVDVMVNLQFTLVETLWKTFWRYNLSQPSEAPPLAVHDEAEKRLPRASLVLLSKFQPVLQWTKHCDNVLYQGLVEILIPDVLRPIPSALTQAIRNFAKSLESWLTHAMVNIPEEMLRVKVAAAGAFAQTLRRYTSLNHLAQAARAVLQNTAQINQMLSDLNRVDFANVQEQASWVCRCEDRVVQRLEQDFKVTLQQQNSLEQWAAWLDGVVSQVLKPYQGSSGFPKAAKLFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMYYLIEHRVAQAKGETPIAVMGEFANLATSLNPLDPDKDEEEEEEEESEDELPQDISLAAGSESPALGPEALEPPAKLARTDTRGLFVQALPSS
What is the function of this protein?
Regulatory factor essential for MHC class II genes expression.  Binds to the X boxes of MHC class II genes (By similarity).
What are the official names of this protein?
MHC class II regulatory factor RFX1, Regulatory factor X 1, Transcription factor RFX1.
What is the protein family that this protein belongs to?
Belongs to the RFX family.
What are the subcellular locations of this protein?
Nucleus.
Protein: 2MMP_ARATH
Sequence: MRFCVFGFLSLFLIVSPASAWFFPNSTAVPPSLRNTTRVFWDAFSNFTGCHHGQNVDGLYRIKKYFQRFGYIPETFSGNFTDDFDDILKAAVELYQTNFNLNVTGELDALTIQHIVIPRCGNPDVVNGTSLMHGGRRKTFEVNFSRTHLHAVKRYTLFPGEPRWPRNRRDLTYAFDPKNPLTEEVKSVFSRAFGRWSDVTALNFTLSESFSTSDITIGFYTGDHGDGEPFDGVLGTLAHAFSPPSGKFHLDADENWVVSGDLDSFLSVTAAVDLESVAVHEIGHLLGLGHSSVEESIMYPTITTGKRKVDLTNDDVEGIQYLYGANPNFNGTTSPPSTTKHQRDTGGFSAAWRIDGSSRSTIVSLLLSTVGLVLWFLP
What is the function of this protein?
Matrix metalloproteinases (MMPs) or matrixins may play a role in the degradation and remodeling of the extracellular matrix (ECM) during development or in response to stresses (By similarity).  Required for plant growth, morphogenesis, and development with particular relevance for flowering and senescence (PubMed:11726650).  Active on McaPLGLDpaAR-NH(2) (QF24) and myelin basic protein (MBP) and, to some extent, on beta-casein (PubMed:24156403).
What are the official names of this protein?
Metalloendoproteinase 2-MMP, At2-MMP.
What is the protein family that this protein belongs to?
Belongs to the peptidase M10A family. Matrix metalloproteinases (MMPs) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor; Extracellular side.
Protein: RL25_CORU7
Sequence: MAELTRIEGVLRTEFGKGASRRLRRDGRIPLVVYGNELDPVHVHVDTLDLHALVRNEGVNAVFELNIDGEDNLVMVKAIDQNVLTLDIDHADLLNVKRGERVEVEVPVIHEGLPAPGAMVVQDVDVLLLEVDVLDIPEEIVLDINGLEIGEQILAKDVKMPSNAVLVSDAEELVINIVEPEEEELPEDDEAAAEGEDAAAGEEAEAPAESED
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: YBEY_SHESH
Sequence: MNTSQAEIELDLDLQLAIENSQLPSKQNFELWVRTALPKTMAEAELTIRIVDEAESQELNSTYRGKDKPTNVLSFPFEAPPEIEIPLLGDLIICAPVVELEALQQNKPLQAHWAHMVVHGCLHLLGYDHINDAEAEEMESLETQLVESLGFNNPYKEQ
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_STRPN
Sequence: MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKHQRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: EFP_HAEIN
Sequence: MATYTTSDFKPGLKFMQDGEPCVIVENEFVKPGKGQAFTRTRIRKLISGKVLDVNFKSGTSVEAADVMDLNLTYSYKDDAFWYFMHPETFEQYSADAKAVGDAEKWLLDQADCIVTLWNGAPITVTPPNFVELEIVDTDPGLKGDTAGTGGKPATLSTGAVVKVPLFVQIGEVIRVDTRSGEYVSRVK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_SHEAM
Sequence: MAIGLIGRKVGMTRIFTEDGVSIPVTVIEVEANRVTQVKTLENDGYRALQVTTGAKKAHRVTKPEAGHFAKAGVEAGRGLWEMRLGEGEGEGIEVGAELNVEIFADVQKVDVTGQSKGKGFQGGVKRWNFRTQDMTHGNSLSHRANGSIGQNQTPGRVFKGKKMSGHMGAERVTTQNLDVVRVDVERNLLLVKGAVPGATNGDLIIKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: IF2P_PONAB
Sequence: MGKKQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRVNSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDSSFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEESETGKKDQSKQKESQRKSEEETVKSKVTLDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNTVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAKRRIEKRRLEHSKNVNTEKLRAPIICVLGHVDTGKTKILDKLRHTHVQDGEAGGITQQIGATNVPLEAINEQTKMIKNFGRENVRIPGMLIIDTPGHESFSNLRNRGSSLCDIAILVVDIMHGGEPQKMKPTNLPKPKKCPFMVALNKIDRLYDWKKSPDSDVAATLKKQKKNTKDEFEERAKAIIVEFAQQGLNAALFYENKDPRTFVSLVPTSAHTGDGMGSLIYLLVELTQTMLSKRLAHCEELRAQVMEVKALPGMGTTIDVILINGRLKEGDTIIVPGVEGPIVTQIRGLLLPPPMKELRVKNQYEKHKEVEAAQGVKILGKDLEKTLAGLPLLVAYKEDEIPVLKDELIHELKQTLNAIKLEEKGVYVQASTLGSLEALLEFLKTSEVPYAGINIGPVHKKDVMKASVMLEHDPQYAVILAFDVRIERDAQEMADSLGVRIFSAEIIYHLFDAFTKYRQDYKKQKQEKFKHIAVFPCKMKILPQYIFNSRDPIVMGVTVEAGQVKQGTPMCVPSKNFVDIGIVTSIEINHKQVDVAKKGQEVCVKIEPIPGESPKMFGRHFEATDILVSKISRQSIDALKDWFRDEMQKSDWQLIVELKKVFEII
What is the function of this protein?
Plays a role in translation initiation.  Translational GTPase that catalyzes the joining of the 40S and 60S subunits to form the 80S initiation complex with the initiator methionine-tRNA in the P-site base paired to the start codon.  GTP binding and hydrolysis induces conformational changes in the enzyme that renders it active for productive interactions with the ribosome.  The release of the enzyme after formation of the initiation complex is a prerequisite to form elongation-competent ribosomes.
What are the official names of this protein?
Eukaryotic translation initiation factor 5B, eIF-5B, Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3NO2A_NAJSP
Sequence: MKTLLLTLVVVTIVCLDLGYTLTCLNCPEVFCKKFQTCRNGEKICFKKFDERKLFGKRYRRGCAATCPEAKPREIVQCCSTDRCNR
What is the function of this protein?
Binds with low affinity to muscular (alpha-1-beta-1-delta-epsilon/CHRNA1-CHRNB1-CHRND-CHRNE) and very low affinity to neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR).
What are the official names of this protein?
Weak neurotoxin 10, Wntx-10.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Ancestral subfamily. Orphan group II sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PSBO_WHEAT
Sequence: MAASLQAAATVMPAKIGGRASSARPSSHVARAFGVDAGARITCSLQSDIREVASKCADAAKMAGFALATSALLVSGATAEGAPKRLTFDEIQSKTYMEVKGTGTANQCPTIDGGVDSFPFKAGKYEMKKFCLEPTSFTVKAEGIQKNEPPRFQKTKLMTRLTYTLDEMEGPLEVRRRRTLKFEEKDGIDYAAVTVQLPGGERVAFLFTVKQLVATGKPESFRPFLVPSYRGSSFLDPKGRGGSTGYDNAGALPRGGRGDEEELAKENVKNASSSTGNITLSVTKSKPETGEVIGVFESVQPSDTDLEAPKDVKIQGVWYAQLESN
What is the function of this protein?
Stabilizes the manganese cluster which is the primary site of water splitting.
What are the official names of this protein?
Oxygen-evolving enhancer protein 1, chloroplastic, OEE1, 33 kDa subunit of oxygen evolving system of photosystem II, 33 kDa thylakoid membrane protein, OEC 33 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the PsbO family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane. Note=Associated with the photosystem II complex.
Protein: PUR7_CHLPM
Sequence: MIMNKTTLLHEGKAKKVFLTDDADLVIQEFKDDATAFNNKKKGSIADKGVVNNAISCRLFTMLEEHGVNTHLVEKLSDRDMLCRRLDIIKVEVVVRNIAAGSLVRRYGFTEGTVLARPIVEFYLKDDDLDDPLMIAEHAVALGVATMDELEVLKSRAGAINDVLKKFFADRRLKLVDFKLEFGRHKGEILLGDEISPDTCRFWDLDTDEKMDKDRFRFDLGGVEDAYTEVQRRVLELD
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: BPT_PARP8
Sequence: MTHPNELPLSPLSALQFYATAPYPCSYLEGRVARSQVATPSHLINSDVYTELVRAGFRRSGVFTYRPYCDGCRACVPVRVPVERFTPNRTQRRVWKKHGGLIATVAPLHYDEEHYALYMRYQSARHAGGGMDRDSRDQYEQFLLQSRINSRLVEFREPPNPGYAGHPDMPGTLRMVSMIDILGDGLSSVYTFFDPDQPHTSYGTYNILWQIEQARSLKLPHVYLGYWIRESPKMAYKANFTPLEGLFDGTWKVLDPAAPDLSPVDAAKGGSRGLRIDRG
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPS3_HUMAN
Sequence: MVQLYNLHPFGSQQVVPCKLEPDRFCGGGRDALFVAAGCKVEAFAVAGQELCQPRCAFSTLGRVLRLAYSEAGDYLVAIEEKNKATFLRAYVNWRNKRTENSRVCIRMIGHNVEGPFSKAFRDQMYIIEMPLSEAPLCISCCPVKGDLLVGCTNKLVLFSLKYQIINEEFSLLDFERSLIIHIDNITPVEVSFCVGYVAVMSDLEVLIVKLESGPKNGERVHHHPHKTNNRIRRTEEGISNEISQLESDDFVICQKPLELLGEKSEQSGLSVTLESTGLADEKRKYSHFQHLLYRRFAPDISSYVLSDDIKLHSLQLLPIYQTGSLTSDGKNLSQEKELLSLFCFFSLPHVGYLYMVVKSVELMSVYQYPEKSQQAVLTPQFLHVITSNNLQCFTVRCSAAAAREEDPYMDTTLKACPPVSMDVCALRIQLFIGLKAICHFKNHIILLTKAEPEAIPERRQSPKRLLSRKDTSVKIKIPPVAEAGWNLYIVNTISPVQLYKEMVDYSNTYKTVKTQSCIHLLSEAHLLVRAALMDASQLEPGEKAELLEAFKESCGHLGDCYSRLDSQHSHLTLPYYKMSGLSMAEVLARTDWTVEDGLQKYERGLIFYINHSLYENLDEELNEELAAKVVQMFYVAEPKQVPHILCSPSMKNINPLTAMSYLRKLDTSGFSSILVTLTKAAVALKMGDLDMHRNEMKSHSEMKLVCGFILEPRLLIQQRKGQIVPTELALHLKETQPGLLVASVLGLQKNNKIGIEEADSFFKVLCAKDEDTIPQLLVDFWEAQLVACLPDVVLQELFFKLTSQYIWRLSKRQPPDTTPLRTSEDLINACSHYGLIYPWVHVVISSDSLADKNYTEDLSKLQSLICGPSFDIASIIPFLEPLSEDTIAGLSVHVLCRTRLKEYEQCIDILLERCPEAVIPYANHELKEENRTLWWKKLLPELCQRIKCGGEKYQLYLSSLKETLSIVAVELELKDFMNVLPEDGTATFFLPYLLYCSRKKPLT
What is the function of this protein?
Involved in early stages of melanosome biogenesis and maturation.
What are the official names of this protein?
BLOC-2 complex member HPS3, Hermansky-Pudlak syndrome 3 protein.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytosol.
Protein: MDM12_CANGA
Sequence: MSFEINWEKLSSDSDLTSNIREGLNGYFQELELPSYVRAIELVDFGFGKIAPNITLREISSPLQDFYDAVNEEYEEDNETSSEMHGRDGQNVGESGEEAVVEKKETDTQFLIEFEYKGDMSLTLTAELVLNYPVERFMTLPLKISISNIGLHSLCLVSYLAKQVFISMLCDVSDPVLDDVDCVLDPNGPVLLANKPLERISIIRSMKIETEIGDRFKDDGSTLRSVGQLEEFIVQKLKDFLRKELAWPSWVNLDFND
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.  The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 12, Mitochondrial inheritance component MDM12.
What is the protein family that this protein belongs to?
Belongs to the MDM12 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: MURC_PROM3
Sequence: MSLWFCPLTSTLSRQQPIHFIGVGGIGMSALALILVNRGHIVSGSDPRENTTVERLRAQGVRVFRDQSAANINAICSNVDLLPLVVISTAIPKSNPELKAAKLSQLKILHRSDLLAALIQAQPSIAVAGSHGKTTTSTLLTTLLATTDQDPTAVIGGVVPYYDSNGHAGKGRLLVAEADESDGSLVKFQATLGVITNLELDHTDHYADLDELINTMKRFGRGCRRLLANFDCPILKEHFDATAWWSVKTSAGVDFAALPICLNGDQTIADIYEQGKRMGQITLPMPGLHNLSNAMAAIAACRLAGLSFEDLQQGLADLQPPGRRFDFRGTWEGRQIVDDYAHHPSEVSATLAMARLIVTSGRSQLPSPPKRILAVFQPHRYSRTNEFLYEFARALGEADAVLLAPVYSAGENPIQGATSESLANAIRIQHPNLPVAVAENFNQLTLLVQKHSLKGDLVLAMGAGNINNLWRQLTRLDNAKTCPPSLAA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOD_RHOE4
Sequence: MSIFLVTGTSTDVGKTVVTAALASVALQSGKSVAVLKPAQTGVDVDGAGDLAEIERLTGGGVTLVELARYPEPLAPDTAARRSGLPLLALDDVVRVARDLDTTHDLTLIEGAGGLLVRLGVDGFTARDLAAALAAPVVLVVASGLGTLNHTALTVEALGASGVECAGLVIGSWPQEPDLAERCNREDLVSVSGVPLLGLMPAGSGSESVQEFAQTAWGALGKSPLAI
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDC_SERP5
Sequence: MDSQRNLLLIALLFVSFMIWQAWQTDNAPQPVAQTTQQTSNPATGDAASSAVPASGQGKLITVNTDVLSLTINTRGGDIEQAKLLAYPDTLGSSTPFQLLETTPAFVYQAQSGLTGRNGPDNPANGERPLFQAAQDSYTLPEGQEELRIPLTFTGKDGAIYTKTFVLKRNHYAVAVDYNVDNKSTTPLELTLFGQLKQTTELPKHRDTGSNNFALHTFRGAAYSSSDDKYQKYAFDKDENLSVTTQGGWVAMLQQYFATAWVPATQGSNTFYTAKPGDNLSTIGFKSTPVVVQPGAQQQLNATLWVGPELQDQMAQLAPHLDLTVDYGWLWFISQPLFKLLKFIHGFIGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKLQAMRERIGDDKQRMSQEMMALYKSEKVNPLGGCLPLVIQMPIFLALYYMLMGSVELRHAPFALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTILQQQLIYRGLEKRGLHSRDKKKT
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ORC1_HUMAN
Sequence: MAHYPTRLKTRKTYSWVGRPLLDRKLHYQTYREMCVKTEGCSTEIHIQIGQFVLIEGDDDENPYVAKLLELFEDDSDPPPKKRARVQWFVRFCEVPACKRHLLGRKPGAQEIFWYDYPACDSNINAETIIGLVRVIPLAPKDVVPTNLKNEKTLFVKLSWNEKKFRPLSSELFAELNKPQESAAKCQKPVRAKSKSAESPSWTPAEHVAKRIESRHSASKSRQTPTHPLTPRARKRLELGNLGNPQMSQQTSCASLDSPGRIKRKVAFSEITSPSKRSQPDKLQTLSPALKAPEKTRETGLSYTEDDKKASPEHRIILRTRIAASKTIDIREERTLTPISGGQRSSVVPSVILKPENIKKRDAKEAKAQNEATSTPHRIRRKSSVLTMNRIRQQLRFLGNSKSDQEEKEILPAAEISDSSSDEEEASTPPLPRRAPRTVSRNLRSSLKSSLHTLTKVPKKSLKPRTPRCAAPQIRSRSLAAQEPASVLEEARLRLHVSAVPESLPCREQEFQDIYNFVESKLLDHTGGCMYISGVPGTGKTATVHEVIRCLQQAAQANDVPPFQYIEVNGMKLTEPHQVYVQILQKLTGQKATANHAAELLAKQFCTRGSPQETTVLLVDELDLLWTHKQDIMYNLFDWPTHKEARLVVLAIANTMDLPERIMMNRVSSRLGLTRMCFQPYTYSQLQQILRSRLKHLKAFEDDAIQLVARKVAALSGDARRCLDICRRATEICEFSQQKPDSPGLVTIAHSMEAVDEMFSSSYITAIKNSSVLEQSFLRAILAEFRRSGLEEATFQQIYSQHVALCRMEGLPYPTMSETMAVCSHLGSCRLLLVEPSRNDLLLRVRLNVSQDDVLYALKDE
What is the function of this protein?
Component of the origin recognition complex (ORC) that binds origins of replication.  DNA-binding is ATP-dependent.  The DNA sequences that define origins of replication have not been identified yet.  ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
What are the official names of this protein?
Origin recognition complex subunit 1, Replication control protein 1.
What is the protein family that this protein belongs to?
Belongs to the ORC1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS20_GRABC
Sequence: MANTASARKRIRQIKVRTERNAARKSRMRTFVKKVETAIASGNHTAANEALREAQPEMQRAAGKGVIHRNTVARRLSRLTARIKALATA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: Y626_NAUPA
Sequence: MAGHNKWSKVKHIKAKEDAKKSKIFTKHVRAIMTAARQGGGNPDTNAALRLAVERAKADSMPMQNIQRAIDKATGNLDGVTLSEVSYEGYGPGGVAIMVECLTDNKNRTVAEIRHAFKKAGGSLGTSGSVAWMFEKKGIVVVNRSDKDDEVMETAIESGAEDIKELNEVLVIETAPEDFNNVLEAVNNIDGIEILESNVQLVATNESEVDDETAEKVEKLIEVLEELDDVQNVIHNMA
What are the official names of this protein?
Probable transcriptional regulatory protein NAMH_0626.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4347_VIBVY
Sequence: MTIEFSNFSFRYESLDKPTLRNINLRIEKGEKIVIIGPSGSGKSTLGQCLNGLIPHAIKGEVSGSLTINGQETATFAMHQFTEQVGTVLQDTDSQFVGLSIGEDIAFALENQLTANIEMYSLVKATAKMVDLEQMLQRSPHDLSGGQKQRVSLAGILVDDVDILLFDEPLAALDPKTGKRTIEIIDDLHRKTGKTVVIIEHRLEDVLHRHVDRIILMDGGEIIADTTPDELLASPLLAQYGIREPLYLTALKSAGCHLALDDHPSSLSELPLANYQHAMADWFHQANTTSNHIRSETLLDVRNLTYSYDGEKNALEGVSFNVQRGEFVSILGKNGSGKSTITKLIMGVIEPDDGTMHLNGQDLSELTIFERSQKVGVVMQNPNHMISHHMIFDEVAFGLRNRGWDEQQVNDKVLEALELCGLSKYRHWPIEALSYGQKKRVTIASILALEPELLMLDEPTAGQDYRNYTSMLSFIEKLNRELGITVVIISHDMHLVLEYTTRSIVIADSQLVADAPMTDVFSNPALLDRANLTTTSLYELATRLNMAETNAFMQHFIDVEKASRLEKTVERNVA
What is the function of this protein?
Probably part of an ABC transporter complex.  Responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Putative ABC transporter ATP-binding protein VVA0347.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: BIOW_SULSY
Sequence: MKFYSVKMRASLNDRHVSGGERITTEESIQKVVSELLTRPKEFDFVNIKIEKINNIKFIEKSLDIKTINVKNHKEGNEIALKLLEEVGIDREIAKAYIDLLHTGANPDRENMRGAMIITRSGKRVEKDRYRGVRTTNVDFLHREEVKKILLEKKYTERTLDALALSTKNLNHLDIIAEYCISDQPDYTTGYVAVNNTYYRINPLKEYSNPKGGRIYFVKDDTDIEELYKYLQEESFLIKEVGSLE
What is the function of this protein?
Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP.
What are the official names of this protein?
6-carboxyhexanoate--CoA ligase, Pimeloyl-CoA synthase.
What is the protein family that this protein belongs to?
Belongs to the BioW family.
Protein: 3SX3_MICMP
Sequence: MKTLLLTLVVVTIVCLDLGNSLKCYDKLKKEVTCPEGMKFCHKDVLPATHGNSVLVMGCTYSCGLGPRNMCCSTDLCNK
What is the function of this protein?
Snake venom neurotoxin that blocks neuromuscular transmission, presenting a postsynaptic action through the nicotinic acetylcholine receptor (nAChR).  Has no cytotoxic activity.
What are the official names of this protein?
Mipartoxin-3, Mipartoxin-III, Three-finger toxin-04, 3FTx-04.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GLYM_CANAX
Sequence: MLSSTLRRSVRAQSKNLPAFARRTYAVSPSAQALISKSVQDVDPEMADILNQERTRQKNSITLIPSENFTSKAVMDLLGSEMQNKYSEGYPGERYYGGNEIIDKAEALCQKRALEAFGLDPSQWGVNVQPLSGAPANLYAYSAILEVGDRIMGLDLPHGGHLSHGYQTKTTKISYISKYFQTMPYRLNEETGIIDYDTLEKNAQLFRPKVIVAGASAYSRVIDYKRMRQLSIRLGAYLLSDMAHISGLVSAVVTDSPFPYSDIVTTTTHKSLRGPRGAMIFFRKGIRKVTTKGKEIPYELERKINFLVFPGHQGGPHNHTISALAVALKQCTEPEYVKYQQEVVSNAKHFADALVSKGFKLVSDGTDTHLILVDLRSRNIDGARVEAVLERANIAANKNTVPGDVSALFPSGLRVGTPAMTTRGFGPEEFDKVAEFIDQAVNIAIELKAQEQGKVPKELLASFKKLADESDKVKQLDKEVVSWVSKYPVPGEL
What is the function of this protein?
Interconversion of serine and glycine.
What are the official names of this protein?
Serine hydroxymethyltransferase, mitochondrial, SHMT, Glycine hydroxymethyltransferase, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TATA_METS4
Sequence: MGGASIWHWIVVGVIVMLLFGRGKVSELMGDVAKGIKAFKKGMADEDQPQAPVVAAPPVTATEPVRTLPPHPTEPAPATHATVDRKVV
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.