PharMolix/UniProtQA huggingface dataset:
Protein: KCY_AQUAE
Sequence: MKIAIDGPSASGKSTVAKIISQKLNIPYLETGLVYRTYAYVSLKFKVPIQDIDKLFSLPVKVVPKIGKTEVYIEGKPVNEEDLRSEEVGKRASELGSIPEFRERINKLFKEIINNKQMVVEGRDAGTHIIPEAPVKVFITASPEERAKRRYEQLKELGYEVSFEEILQKILERDKRDMERPKYPFKPAEDAVIIDTTRKSVEEVVEEVLKIIHERSQSAELI
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_COLP3
Sequence: MSDTTLSEATSNTASHSLAEKRKILVTCALPYANGSIHLGHMLEHIQTDIWVRFQRMRGHETYFVCADDAHGTPIMLKAQELGITPEEMINGVREERIKEFSDFHISFDNYHTTHSDENKEYSEKIYNALHAKGHIKTRIISQLYDPEKGMFLADRFVKGTCPKCKSEDENGDSCDNCGATYSPTEVLNPRSAISGATPILKDSEHYFFDLPAFETMLSDWIRSGALQEEVANKLTEWFEQGLKQWDISRDAPYFGFEIPNAPGKFFYVWLDAPIGYMGSFKNLCDKDSTIDFDSFWNKNSDAELYHFIGKDIINFHSLFWPAMLEGADFRKPTAVFAHGFVTVNGEKMSKSKGTFIKGRTYLDHLNPEYLRYYYATKLTHKIDDLDLNLEDFVQRVNSDLVGKVVNIASRCASFITKRFDGMLSTNIDDQALADEVMAAGDSIAAHYESRDFGRGMREIMALADKVNEYIAIKEPWQLVKDETKQQEVQDICSLGINMFRTLMIYLKPVLPVLADSTAAFLNDELVWEGHKTLLTDHKINKFKALLQRVDMDKVNAMTDASKDSLGAPVEEEKKPAKKKKAAKVVDNSAALADPLAADPISEEIEFDDFAKIDLRIVKIINAEHVEKADKLIQLTLALNEEGTETRQVFAGIKSAYNPEDLIGKHTVMVANLAPRKMRFGMSEGMVLAAGPGDKDLWILNPDDGAKAGMRVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUP_SCHPO
Sequence: MLFLKLVASVLALMTIVPAQAGLIGKRSVFKPKVMIINMFSLEANAWLSQMDDLYANNITVVGLNRLYPQVHCNTQQTICQMTTGEGKSNAASSIMALTLSPKFDLTETFFLISGIAGINPYAASLGSVGVARFAVDIDLINSVDLRELPSYFQSSGWEIDTDPYENGSSNEIVYPESMPYQTNLYELNNTLITAAMEIIKDVVLEDNEKAASYRKLYNESAARRPPFITQCDTATGDNYWAGTYMGDFVSNITNVLTNSTGHYCTTQQEDNASLTALTRASFDGLVNINRVVIMRSGSDFDRGAGNITALANLLNSTGHVSSLACDNLYHAGAPLIDHIVNHWSYWT
What is the function of this protein?
Probable nucleoside permease that transports adenosine and guanosine.
What are the official names of this protein?
Probable purine nucleoside permease C285.05.
What is the protein family that this protein belongs to?
Belongs to the NUP family.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: SAHH_RALPJ
Sequence: MNAVTDLKHDYLVADIKLADWGRKEIAIAETEMPGLMAIRDEFAASQPLKGARIAGSLHMTIQTAVLIETLKALGADVRWASCNIFSTQDHAAAAIAATGTPVFAFKGESLQEYWDFTHRIFEWADGGTPNMILDDGGDATLLLHLGAKAEKDVSVLAHPGSEEETFLFAAIKEKLAKDATFYSRNLDAIKGVTEETTTGVHRLYQMAQRGELRFPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMIAGKVAIVAGYGDVGKGSAQALRALSAQVWVTEIDPICALQAAMEGYRVVTMDYAAEHGDIFVTCTGNYHVITHDHMAKMKDQAIVCNIGHFDNEIDIASVEKYQWEEIKPQVDHVIFPDGKKIIILAKGRLVNLGCATGHPSYVMSSSFANQTIAQIELWTEAVKGSNKYPVGVYTLPKHLDEKVARLQLKKLNAQLTELTDQQAAYIGVSKEGPYKADHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LFTR_PHOLL
Sequence: MMPIIQLNADSYDFPHPKEALTEPNGLLAVGGDLSAKRLNAAYHQGIFPWFLPSEMPLWWSPDPRAVIIPGELHIGRTLRRFLRNTPYHITVNHAFEQVVHFCAQRQEGTWIGKDIQQGYKKLYQTGQAHSVEVWHNERIVGGLYGVSVGTLFCGESMFSRMENASKCAFIAFYHHFLRHGGELLDCQVLNHHTASLGAKEIPREEFIQYLYQFRNRSLKAGCWLQQVLEL
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FND3A_HUMAN
Sequence: MAEHPPLLDTTQILSSDISLLSAPIVSADGTQQVILVQVNPGEAFTIRREDGQFQCITGPAQVPMMSPNGSVPPIYVPPGYAPQVIEDNGVRRVVVVPQAPEFHPGSHTVLHRSPHPPLPGFIPVPTMMPPPPRHMYSPVTGAGDMTTQYMPQYQSSQVYGDVDAHSTHGRSNFRDERSSKTYERLQKKLKDRQGTQKDKMSSPPSSPQKCPSPINEHNGLIKGQIAGGINTGSAKIKSGKGKGGTQVDTEIEEKDEETKAFEALLSNIVKPVASDIQARTVVLTWSPPSSLINGETDESSVPELYGYEVLISSTGKDGKYKSVYVGEETNITLNDLKPAMDYHAKVQAEYNSIKGTPSEAEIFTTLSCEPDIPNPPRIANRTKNSLTLQWKAPSDNGSKIQNFVLEWDEGKGNGEFCQCYMGSQKQFKITKLSPAMGCKFRLSARNDYGTSGFSEEVLYYTSGCAPSMPASPVLTKAGITWLSLQWSKPSGTPSDEGISYILEMEEETSGYGFKPKYDGEDLAYTVKNLRRSTKYKFKVIAYNSEGKSNPSEVVEFTTCPDKPGIPVKPSVKGKIHSHSFKITWDPPKDNGGATINKYVVEMAEGSNGNKWEMIYSGATREHLCDRLNPGCFYRLRVYCISDGGQSAVSESLLVQTPAVPPGPCLPPRLQGRPKAKEIQLRWGPPLVDGGSPISCYSVEMSPIEKDEPREVYQGSEVECTVSSLLPGKTYSFRLRAANKMGFGPFSEKCDITTAPGPPDQCKPPQVTCRSATCAQVNWEVPLSNGTDVTEYRLEWGGVEGSMQICYCGPGLSYEIKGLSPATTYYCRVQALSVVGAGPFSEVVACVTPPSVPGIVTCLQEISDDEIENPHYSPSTCLAISWEKPCDHGSEILAYSIDFGDKQSLTVGKVTSYIINNLQPDTTYRIRIQALNSLGAGPFSHMIKLKTKPLPPDPPRLECVAFSHQNLKLKWGEGTPKTLSTDSIQYHLQMEDKNGRFVSLYRGPCHTYKVQRLNESTSYKFCIQACNEAGEGPLSQEYIFTTPKSVPAALKAPKIEKVNDHICEITWECLQPMKGDPVIYSLQVMLGKDSEFKQIYKGPDSSFRYSSLQLNCEYRFRVCAIRQCQDSLGHQDLVGPYSTTVLFISQRTEPPASTNRDTVESTRTRRALSDEQCAAVILVLFAFFSILIAFIIQYFVIK
What is the function of this protein?
Mediates spermatid-Sertoli adhesion during spermatogenesis.
What are the official names of this protein?
Fibronectin type-III domain-containing protein 3A, Human gene expressed in odontoblasts.
What is the protein family that this protein belongs to?
Belongs to the FNDC3 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass membrane protein.
Protein: TREF_SHIBS
Sequence: MLNQKIQNPNPDELMIEVDLCYELDPYELKLDEMIEAEPEPEMIEGLPASDALTPADRYLELFEHVQSAKIFPDSKTFPDCAPKMDPLDILIRYRKVRRHRDFDLRKFVENHFWLPEVYSSEYVSDPQNSLKEHIDQLWPVLTREPQDHIPWSSLLALPQSYIVPGGRFSETYYWDSYFTMLGLAESGREDLLKCMADNFAWMIENYGHIPNGNRTYYLSRSQPPVFALMVELFEEDGVRGARRYLDHLKMEYAFWMDGAESLIPNQAYRHVVRMPDGSLLNRYWDDRDTPRDESWLEDVETAKHSGRPPNEVYRDLRAGAASGWDYSSRWLRDTGRLASIRTTQFIPIDLNAFLFKLESAIANISALKGEKETEALFRQKASARRDAVKRYLWDDENGIYRDYDWRREQLALFSAAAIVPLYVGMANHEQADRLANAVRSRLLTPGGILASEYETGEQWDKPNGWAPLQWMAIQGFKMYGDDLLGDEIARSWLKTVNQFYLEQHKLIEKYHIADGVPREGGGGEYPLQDGFGWTNGVVRRLIGLYGEP
What is the function of this protein?
Hydrolyzes trehalose to glucose.  Could be involved, in cells returning to low osmolarity conditions, in the utilization of the accumulated cytoplasmic trehalose, which was synthesized in response to high osmolarity.
What are the official names of this protein?
Cytoplasmic trehalase, Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 37 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_STRSY
Sequence: MATTITMQSSTILGNFILVTASFAVLIILIRVFAWDKITGIFEERANKIANDIDAAEEKLTAAANLVQQREDELVQGRIESQKIIQDAVERAKLEKKRILEQADVEIQGLKQKAQLEIEAEKREAQENLRVQVAELAVDLASKIILEDLDQQAHSNLIDRYLDKLGDK
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: HEM1_SHEPC
Sequence: MSLVAIGINHKTATVDLREKVAFSPDKIHDAMKSLASRTRSGEAVIVSTCNRTELYCNNGDEADIIEWLEEYHGLDHKDVAPCLYNYHGQTAVKHLMRVASGLDSLILGEPQILGQVKQAFAKAKEAGTVALTIDRLFQNTFSVAKKVRTETEIGAAAVSVAFAAVSMAKHIFSSLSTTKVLLIGAGETIELVAKHLKDNGVASMVVANRTLERAQGMCEEFGATAITLAQIPDYLPKADIVISSTASPLPILGKGMVEKALKQRRHQPMLLVDIAVPRDIEPEVADLDDAFLYTVDDLHSIIEQNMASRKEAAEQAELITEEQSYLFMDWVRSLESVDSIREYRNQSMAIKDELVERALNKLAQGGDTEQVLIELANRLTNKLIHAPTQALTAASRQGDLNTLGQLRTALGLDKN
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: VPC47_MYCTU
Sequence: MIYMDTSALTKLLISEPETTELRTWLTAQSGQGEDAATSTLGRVESMRVVARYGQPGQTERARYLLDGLDILPLTEPVIGLAETIGPATLRSLDAIHLAAAAQIKRELTAFVTYDHRLLSGCREVGFVTASPGAVR
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  An RNase (By similarity).  Upon expression in M. smegmatis inhibits translation and colony formation.  Its toxic effect on colony formation is neutralized by coexpression with cognate antitoxin VapB47; the effect on translation has not been tested but is probably neutralized also.
What are the official names of this protein?
Ribonuclease VapC47, RNase VapC47, Toxin VapC47.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: DF255_ARATH
Sequence: MRSISFKLLLLVSLLVVVSRYTLAYEDSCSTDEECRRNCLCDVAYCDKSRDKCDYGFMNRVDVRFPKHPYISKNKDGSGR
What are the official names of this protein?
Defensin-like protein 255.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: IF2_LACDB
Sequence: MTKKQENETSKELGMDNKKTSGKSGKLKISVSAIRKGEKKTEGKRSNARRRANNHSNDHSKRRRPAAQDLLKDLKQKQRADEARLDQESKAAKQEYKKSLNKAEASESKPVVKKVESVEKPAETAAEAPKVRGPKILKPSPARLKQNQANSEKPAAKPSSSRRPSSRPSFTEAPMPENKEGRRRKSGKPGRKGQNSYADQGRGANSNRSEQRKRKNKKHQSAPQVKKQVTQRKDRPLPESFEYEVGMNAQDLGKILHREPAEIVKKLFMLGIMINQNRSLDKDTIELLAADYGIEAVEKVHEDISDIDNIFAQEMEESKNSENQVVRPPVVTIMGHVDHGKTTLLDRLRHTRVSEHEAGGITQNIGAYQVRINDRLITFLDTPGHAAFSSMRARGAEITDIVVLIVAADDGVMPQTIEAIDHAKSAGVPIIVAINKMDRPGANPAHVTEQLMQYELIPENYGGSTIFVNISAKTGMGIDELLENIILEADMLELKADPKQKAIGTVVEARLSRGKGPVADVLIQQGTLRVGDPIVVGDTFGRVRTMTNDKGHQVKKATPSMPVEITGLNDVPESADKLVVFADEKTARAVGEARAQQSLQKQRENVQHVTLDNLFDTMKRESMKSVDIVLKADVQGSAEALAQSFQKIDVEGVRVNIIHSGVGAINESDVTLASASNALIIGFNVRPTATAKSQAAQEGVDIRLYSIIYKAIDDVKAAMQGMLEPTYEEKVIGNLTVRETWKVSKIGTIAGAFVDNGYVTRESGIRVIRDGVVKYDGKVASLRRFKDDVKEVKAGFDCGLTIENFNDIKEGDELEAYEMQEVKPG
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IOVO_SYRMI
Sequence: AVSVDCSEYPKPACTMEYRPLCGSDNKTYGNKCNFCNAVVESNGTLTLSRFGKC
What are the official names of this protein?
Ovomucoid.
What are the subcellular locations of this protein?
Secreted.
Protein: MLRA_PIG
Sequence: MASRKAGTRSKAAATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKSDLRETYSQLGKVNVPEEELDAMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRLFDPSGKGVVNKDQFKQLLLTQADKFSPAEVEQMFALTPMDLAGNIDYKSLCYIITHGDEKEE
What are the official names of this protein?
Myosin regulatory light chain 2, atrial isoform, MLC-2a, MLC2a, Myosin light chain 2a, Myosin regulatory light chain 7.
Protein: SYP_RHILW
Sequence: MRLSRYFMPILKENPKEAEIVSHRLMLRAGMIRQQSQGIYSWLPLGKRVLDKVNAIIRDEQNRAGAIELSMPTLQSAELWQESGRYDAYGKEMLRIKDRQDRPMLYGPTNEEMVTDIFRSSVKSYKDLPLNLYHIQLKFRDEIRPRFGTMRSREFMMKDAYSFDLTREGAEHSYNKMFAAYLRTFDRLGLRAIPMRADTGPIGGNLSHEFIILADTGESEVFCHKDFVGFDIPDDRTDFDSVDGLKAIFDKWTSLYAATSEMHDEAAFNAVPEGDRLSARGIEVGHIFYFGTKYSEAMGAKVQGPDGKEHFVHMGSYGIGPTRLVPAIIEASHDDNGIIWPASVAPFDIVVINMKAGDQACDDTCELIYAALTKAGKDVLYDDTDDRAGTKFATADLIGVPFQIIAGPRAVANGEVEVKDRKTGARETMTIEAAINRFVA
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPF_ENT38
Sequence: MRIGHGFDVHAFGGVGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLTHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLVKAAK
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: RHLB_SALSV
Sequence: MSKTHLTEQKFSDFALHPQVVEALEKKGFYNCTPIQALALPLTLAGRDVAGQAQTGTGKTMAFLTSTFHYLLSHPAIDDRKVNQPRALIMAPTRELAVQIHADAEPLAQATGLKLGLAYGGDGYDKQLKVLESGVDILIGTTGRLIDYAKQNHINLGAIQVVVLDEADRMYDLGFIKDIRWLFRRMPPAAQRLNMLFSATLSYRVRELAFEQMNNAEYVEVEPEQKTGHRIKEELFYPSNEEKMRLLQTLIEEEWPDRAIIFANTKHRCEDIWGHLAADGHRVGLLTGDVAQKKRLRILDEFTRGDLDILVATDVAARGLHIPAVTHVFNYDLPDDCEDYVHRIGRTGRAGASGHSISLACEEYALNLPAIESYIGHSIPVSKYNPEALMNDLPKPLRLTRSRPGNGPRRAGAPRNRRRSG
What is the function of this protein?
DEAD-box RNA helicase involved in RNA degradation.  Has RNA-dependent ATPase activity and unwinds double-stranded RNA.
What are the official names of this protein?
ATP-dependent RNA helicase RhlB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. RhlB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_RHOPS
Sequence: MAIPEFTMRQLLEAGVHFGHQSHRWNPKMAEYIFGARNNIHIIDLAQTVPLMHRALQAISDTVAKGGRVLFVGTKRQAQDAVADAAKRSAQYFVNSRWLGGTLTNWKTISGSIKRLRHLDDVLNSGDASAYTKKERLTLQRERDKLDRSLGGIKDMGGLPDLIFVIDTNKEDIAIQEAQRLGIPVAAIVDTNCDPKGITYLVPGNDDAGRAIALYCDLIARAVIDGISRAQGDSGIDIGAASRPLREDLPAAQATGFQGLSGPRGTPDDLKKLTGVSGDIEKKFNDLGIFHYWQFAELDHDTVLQIGEEVGLPGRADGWVAQAKGLTAEAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: SECA_LEGPC
Sequence: MLSTLIKKMFGSRNERTLRRMEKSVMAINAFEPKMQALSNEELAGKTQEFKERFNNGESLDELLAEAFATVREVSLRTLGLRHFDVQLIGGMVLHEGNIAEMRTGEGKTLVATLPAYLNAISGRGVHIVTVNDYLAKRDSQWMKPIYEFLGLTVGVIYPDMSHKEKQEAYKADIVYGTNNEYGFDYLRDNMAFSLTDKVQRELNFAIVDEVDSILIDEARTPLIISGAAEDSSELYIKINSLIPQLKKQEEEGDEGDYTIDEKQKQAHLTDAGHLHIEELLTKAKLLDPGESLYHASNIMLMHHVNAALKAHAMFHRDIDYIVKDNQVVIVDEHTGRTMPGRRWSEGLHQAVEAKEGVPIQNENQTLASITFQNFFRMYNKLSGMTGTADTEAYEFQQIYNLEVVVIPTNRSMIRKDEADLVYLTQADKFQAIIEDVRECGVRKQPVLVGTVSIEASEFLSQLLKKENIKHQVLNAKFHEKEAQIIAEAGRPGAVTIATNMAGRGTDIVLGGSLAADLANLPADASEQEKEAVKKEWQKRHDEVIAAGGLRIIGSERHESRRIDNQLRGRAGRQGDPGSSRFYLSLEDNLMRIFASERVASMMRRLGMQPGEPIEHSLVTRAIENAQRKLEGHHFDVRKQLLDYDNVANDQRQVIYTQRASIMAMTDTQEVVEMMREEVMNSLVDTYIPPQSLEDQWDPQALSDVLSDEFKIKAPVPDWIDKDHSIQPDQIKEKVLALAIEHYDEKVRKVGRPVISQFEKSIILQTLDNHWREHLAAMDQLRQGIHLRGYAQKDPKQEYKKEAFSLFTMMLDNLKYEVIRILSSVEIQTEEDAQVVEEQRRADQIRKMNLMHESLSENDEASETQTFRRQEKKIGRNDPCPCGSGKKYKACHGSLV
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: PSBJ_PROM9
Sequence: MSKLKGPDGRIPDRLPDGRPAVAWERRWTEGTLPLWLVATAGGIAVIFVLGIFFYGSYQGVGAGG
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein J, PSII-J.
What is the protein family that this protein belongs to?
Belongs to the PsbJ family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: PE03_MYCTU
Sequence: MSYVIAAPEMLATTAADVDGIGSAIRAASASAAGPTTGLLAAAADEVSSAAAALFSEYARECQEVLKQAAAFHGEFTRALAAAGAAYAQAEASNTAAMSGTAGSSGALGSVGMLSGNPLTALMMGGTGEPILSDRVLAIIDSAYIRPIFGPNNPVAQYTPEQWWPFIGNLSLDQSIAQGVTLLNNGINAELQNGHDVVVFGYSQSAAVATNEIRALMALPPGQAPDPSRLAFTLIGNINNPNGGVLERYVGLYLPFLDMSFNGATPPDSPYQTYMYTGQYDGYAHNPQYPLNILSDLNAFMGIRWVHNAYPFTAAEVANAVPLPTSPGYTGNTHYYMFLTQDLPLLQPIRAIPFVGTPIAELIQPDLRVLVDLGYGYGYADVPTPASLFAPINPIAVASALATGTVQGPQAALVSIGLLPQSALPNTYPYLPSANPGLMFNFGQSSVTELSVLSGALGSVARLIPPIA
What is the function of this protein?
Plays significant roles in mycobacterial persistence during infection and modulates host immune response.
What are the official names of this protein?
PE family protein PE3.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PE family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: LEG1_SHEEP
Sequence: MACGLVASNLNLKPGECLRVRGEVAADAKSFSLNLGKDDNNLCLHFNPRFNAHGDINTIVCNSKDGGAWGAEQRETAFPFQPGSVAEVCISFNQTDLTIKLPDGYEFKFPNRLNLEAINYLSAGGDFKIKCVAFE
What is the function of this protein?
Lectin that binds beta-galactoside and a wide array of complex carbohydrates.  Plays a role in regulating apoptosis, cell proliferation and cell differentiation (PubMed:9546655).  Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase (By similarity).  Strong inducer of T-cell apoptosis (PubMed:9546655).
What are the official names of this protein?
Galectin-1, Gal-1, 14 kDa lectin, Beta-galactoside-binding lectin L-14-I, Galaptin, Lactose-binding lectin 1, Lectin galactoside-binding soluble 1, OPG-1, S-Lac lectin 1.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Cytoplasm. Secreted. Note=Can be secreted; the secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion.
Protein: DTDA_METKA
Sequence: MRRVVILWNPDDPASKNIAESLTEDAEKLDTEDLQHYTVETWERDGVRFHLTAALGDLIEEDEARELARKFDVIVFASRHESRTKKPSLTVHVPGNPTPEAKFGGKPLEVCTADPAGMKAALLELKRFRDKRGLDYDVCYEVTHHGPRDPGAPCFFIEIGSDEERWTDEEAGEACARAILAAVDPPDVKAVVGYGGGHYAPAHTDAALSNRKLAYGHIVPDYAVDHDYLRDQFREVVDKTPRAREIIVDDRNLDSGIVERLEDLVRDRGLRLRDVEEVK
What is the function of this protein?
D-aminoacyl-tRNA deacylase with broad substrate specificity.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, D-tyrosyl-tRNA(Tyr) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DtdA deacylase family.
Protein: TM175_STRC3
Sequence: MNESGRVEAFSDGVFAIAITLLILDIKVPKADGPGGLWHALGAQWPSYAAYVVSFLVIGIMWVNHHQVFSYVARVDRALMFLNLLVLMVVAAVPWPTAMLAEYLREDRASHVAAAVYSLVMVAMALAFQALWWHLTRTGHLFDPRVDAPAARATRIRFALGSLGYPLTVGLAFVSAPLTLAAHGLLALYYGFNQVPVPTREAAAPS
What is the function of this protein?
Potassium channel.
What are the official names of this protein?
Potassium channel B446_29190.
What is the protein family that this protein belongs to?
Belongs to the TMEM175 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SPIKE_CVPPU
Sequence: MKKLFVVLVVMPLIYGDNFPCSKLTNRTIGNQWNLIETFLLNYSSRLPPNSDVVLGDYFPTVQPWFNCIRNNSNDLYVTLENLKALYWDYATENITWNHRQRLNVVVNGYPYSITVTTTRNFNSAEGAIICICKGSPPTTTTESSLTCNWGSECRLNHKFPICPSNSEANCGNMLYGLQWFADEVVAYLHGASYRISFENQWSGTVTFGDMRATTLEVAGTLVDLWWFNPVYDVSYYRVNNKNGTTVVSNCTDQCASYVANVFTTQPGGFIPSDFSFNNWFLLTNSSTLVSGKLVTKQPLLVNCLWPVPSFEEAASTFCFEGAGFDQCNGAVLNNTVDVIRFNLNFTTNVQSGKGATVFSLNTTGGVTLEISCYTVSDSSFFSYGEIPFGVTDGPRYCYVHYNGTALKYLGTLPPSVKEIAISKWGHFYINGYNFFSTFPIDCISFNLTTGDSDVFWTIAYTSYTEALVQVENTAITKVTYCNSHVNNIKCSQITANLNNGFYPVSSSEVGLVNKSVVLLPSFYTHTIVNITIGLGMKRSGYGQPIASTLSNITLPMQDHNTDVYCIRSDQFSVYVHSTCKSALWDNIFKRNCTDVLDATAVIKTGTCPFSFDKLNNYLTFNKFCLSLSPVGANCKFDVAARTRTNEQVVRSLYVIYEEGDNIVGVPSDNSGVHDLSVLHLDSCTDYNIYGRTGVGIIRQTNRTLLSGLYYTSLSGDLLGFKNVSDGVIYSVTPCDVSAQAAVIDGTIVGAITSINSELLGLTHWTTTPNFYYYSIYNYTNDRTRGTAIDSNDVDCEPVITYSNIGVCKNGAFVFINVTHSDGDVQPISTGNVTIPTNFTISVQVEYIQVYTTPVSIDCSRYVCNGNPRCNKLLTQYVSACQTIEQALAMGARLENMEVDSMLFVSENALKLASVEAFNSSETLDPIYKEWPNIGGSWLEGLKYILPSHNSKRKYRSAIEDLLFDKVVTSGLGTVDEDYKRCTGGYDIADLVCAQYYNGIMVLPGVANADKMTMYTASLAGGITLGALGGGAVAIPFAVAVQARLNYVALQTDVLNKNQQILASAFNQAIGNITQSFGKVNDAIHQTSRGLATVAKALAKVQDVVNIQGQALSHLTVQLQNNFQAISSSISDIYNRLDELSADAQVDRLITGRLTALNAFVSQTLTRQAEVRASRQLAKDKVNECVRSQSQRFGFCGNGTHLFSLANAAPNGMIFFHTVLLPTAYETVTAWPGICASDGDRTFGLVVKDVQLTLFRNLDDKFYLTPRTMYQPRVATSSDFVQIEGCDVLFVNATVSDLPSIIPDYIDINQTVQDILENFRPNWTVPELTFDIFNATYLNLTGEIDDLEFRSEKLHNTTVELAILIDNINNTLVNLEWLNRIETYVKWPWYVWLLIGLVVIFCIPLLLFCCCSTGCCGCIGCLGSCCHSICSRRQFENYEPIEKVHVH
What is the function of this protein?
S1 region attaches the virion to the cell membrane by interacting with host ANPEP/aminopeptidase N, initiating the infection.  Binding to the receptor probably induces conformational changes in the S glycoprotein unmasking the fusion peptide of S2 region and activating membranes fusion.  S2 region belongs to the class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.
What are the official names of this protein?
Spike glycoprotein, S glycoprotein, E2, Peplomer protein.
What is the protein family that this protein belongs to?
Belongs to the alphacoronaviruses spike protein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Note=Accumulates in the endoplasmic reticulum-Golgi intermediate compartment, where it participates in virus particle assembly.
Protein: E4PD_SHISS
Sequence: MTVRVAINGFGRIGRNVVRALYESGRRAEITVVAINELADAAGMAHLLKYDTSHGRFAWEVRQERDQLFVGDDAIRVLHERSLQSLPWRELGVDVVLDCTGVYGSREHGEAHIAAGAKKVLFSHPGSNDLDATVVYGVNQDQLRAEHRIVSNASCTTNCIIPVIKLLDDAYGIESGTVTTIHSAMHDQQVIDAYHPDLRRTRAASQSIIPVDTKLAAGITRFFPQFNDRFEAIAVRVPTINVTAIDLSVTVKKPVKANEVNLLLQKAAQGAFHGIVDYTELPLVSVDFNHDPHSAIVDGTQTRVSGAHLIKTLVWCDNEWGFANRMLDTTLAMATVAFR
What is the function of this protein?
Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
What are the official names of this protein?
D-erythrose-4-phosphate dehydrogenase, E4PDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.