PharMolix/UniProtQA huggingface dataset:
Protein: MURA2_SYMTH
Sequence: MTAKFVVRGGNRLSGTVTIGGAKNSALPIVTAAALAAEGESILENVPDNSDIQHLCEILRALGCRVERVAETTLRIQARELEHHVAPYHLARRLRGSTYVMGLLLARLGKGEVACPGGCEIGARPVDFHLKGFRALGAEVVVEHGAMVSRRVDLRGGRFYVDRASVGTTVNMIITASLAPGVTVLENAACEPEIVDLANFINAMGGRVRGAGTNTVRIEGVDRLRGARHEIIPDRIEAGTYMMMTAAAGGDVVVENVIPEHLGTVIAKLVEAGQEVEEHGDCIRVRARPIRAVDVETQVYPGFPTDLQSPWVALMGLADGISVVHETIFENRFGFTNELIRMGAKIKVDRNTGIIRGVKRYTGAPVEARDIRGGAALVTAALAAEGVTEVSGVQYIDRGYTRMEEKLAALGADIRRVPNGSEQ
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2, Enoylpyruvate transferase 2, UDP-N-acetylglucosamine enolpyruvyl transferase 2, EPT 2.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KN12G_ORYSJ
Sequence: MPSDCGDDDHGGGSAPAGFELQEDPSFWKDNNVQVVIRVRPLSSGEISVQGQKRCVRQDSCQSITWTGHPESRFKFDLVADEYVTQENLFKVAGVPMVDNCMAGYNSCMFAYGQTGSGKTHTMLGDIENGTRRNNVNCGMTPRVFEHLFLRIQKEKEIRKEEKLRFTCKCSFLEIYNEQILDLLNPNSVNLQIREDAKKGVHVENLTEHEVSNAREAMQQLVEGAANRKVAATNMNRASSRSHSVFTCLIESKWESQGINHHRFSRLNLVDLAGSERQKSSGAEGERLKEATNINKSLSTLGLVITNLIAVSNKKSHHVPYRDSKLTFLLQDSLGGNSKTTIIANISPSSCCAAETLSTLKFAQRAKYIRNNAIINEDASGDVLSMRLQIQHLKKEVSRLQGLVNSDKAECTSSSGFICESPSTLKWNQGQGSFSPLMFDKRAMQRKDYDAALVAAFRREQETEAKLKAMIAAKLVAEQLATQRAEEVRSFKMRLRFREDRIKRLEQVTSGKLSAESHLLQENEDLVKEVDALRGLLDRNPEVTRFAMENLQLKEDIRRLQTFVDEGEREMMHEQIIVLQDKLLEALDWKLMHEKDPINKDLSFLGESADEEMEFIRLQAIQNEREIESLRKNLSFCLESKEKLERRVDELTLELEAAKKYHEESEAVELQVQTEVDLHDLPDAQTELKTLVDAIATASQREAEAHETAIGLAKANEELRTRLTVLIEDNKRLVELYEHAIANGEVNQDGGHPAIPQIEGVNEQQSSHSYGGAAANGVLPDDKPESATILPADNSSSEVSDSKIMDGQCNHKDNFSRSELTDLQLQLDEMHEENDKLMGLYEKAMQERDEFKRKFFEGSNSLTTVDTQYEDVEMRDATDDEDLEVKHVHDSAISTFKEILRLVRVKLKNVHDKLVTTQDAVEYFKLLEMASTKAEELSASIQHHCLELKHDQEDMNALKAELSQSQESKEALESKYFSPVASCWNLDLKTKALVGSKFDVSLELLNQKKEQLSHLQTLKKEFSVASTKARESETALRSKIDGLKVKLRSFEAQRKEAERVLFAIDNIDTSTPTLSKPVNFGKASELLRSEEERTKLLSELKKSREQLIMVQKEIKSMNRHDDIDCKIASLESEVENCCLTLLEADVEKFVRDNTLTEIWKEEQKDMDCLLVDYQECVFKVNLKEEKIRACEESLQHQTRSLDDMNSKLNQAMRDLGEHLRDRTPCDLDASMLHVSDKVKGDLDAMALHVAEAVQLLLVQGENQTNP
What are the official names of this protein?
Kinesin-like protein KIN-12G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-12 subfamily.
Protein: NDEL1_PONAB
Sequence: MDSEDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGTENTFPSPKAIPNGFGTSPLTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKSYISGNVNCGVLNGNGTKFSRSGHTSFFDKGAVNGFDPAPPPPGLGSSRPSSAPGMLPLSV
What is the function of this protein?
Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome.  May regulate microtubule organization at least in part by targeting the microtubule severing protein KATNA1 to the centrosome.  Also positively regulates the activity of the minus-end directed microtubule motor protein dynein.  May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus ends.  Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the centripetal motion of secretory vesicles and the coupling of the nucleus and centrosome.  Also required during brain development for the migration of newly formed neurons from the ventricular/subventricular zone toward the cortical plate.  Plays a role, together with DISC1, in the regulation of neurite outgrowth.  Required for mitosis in some cell types but appears to be dispensible for mitosis in cortical neuronal progenitors, which instead requires NDE1.  Facilitates the polymerization of neurofilaments from the individual subunits NEFH and NEFL.  Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts (By similarity).
What are the official names of this protein?
Nuclear distribution protein nudE-like 1, Protein Nudel.
What is the protein family that this protein belongs to?
Belongs to the nudE family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Note=Localizes to the interphase centrosome and the mitotic spindle. Localizes to the cell body of the motor neurons and colocalizes with assembled neurofilaments within axonal processes. Localizes to the microtubules of the manchette in elongated spermatids. Colocalizes with DISC1 in the perinuclear region, including the centrosome. Localizes to the kinetochore in a CENPF- dependent manner (By similarity).
Protein: THIE_SHIF8
Sequence: MYQPDFPPVPFRLGLYPVVDSVQWIERLLDAGVRTLQLRIKDRRDEEVEADVVAAIALGRRYNARLFINDYWRLAIKHQAYGVHLGQEDLQATDLNAIRAAGLRLGVSTHDDMEIDVALAARPSYIALGHVFPTQTKQMPSAPQGLEQLARHVERLADYPTVAIGGISLARAPAVIATGVGSIAVVSAITQAADWRLATAQLLEIAGVGDE
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: DGOD_ECOLU
Sequence: MKITKITTYRLPPRWMFLKIETDEGVVGWGEPVIEGRARTVEAAVHELGDYLIGQDPSRINDLWQVMYRAGFYRGGPILMSAIAGIDQALWDIKGKVLNAPVWQLMGGLVRDKIKAYSWVGGDRPADVIDGIKTLREIGFDTFKLNGCEELGLIDNSRAVDAAVNTVAQIREAFGNQIEFGLDFHGRVSAPMAKVLIKELEPYRPLFIEEPVLAEQAEYYPKLAAQTHIPLAAGERMFSRFDFKRVLEAGGISILQPDLSHAGGITECYKIAGMAEAYDVTLAPHCPLGPIALAACLHIDFVSYNAVLQEQSMGIHYNKGAELLDFVKNKEDFSMVGGFFKPLTKPGLGVEIDEAKVIEFSKNAPDWRNPLWRHEDNSVAEW
What is the function of this protein?
Catalyzes the dehydration of D-galactonate to 2-keto-3-deoxy-D-galactonate.
What are the official names of this protein?
D-galactonate dehydratase, GalD.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
Protein: SAR1_NEUCR
Sequence: MWLWSWFYDILSNLGLLNKHGKLLFLGLDNAGKTTLLHMLKNDRVAILQPTLHPTSEELSVGNVKFTTFDLGGHQQARRLWKDYFPEVNGIVFLVDAKDHERLPEAKAEIDALLSMEELAKVPFVVLGNKIDHPEAVSEDELRQRLGLWQTTGKGRVPLEGIRPIEVFMCSVVMRQGYGEAIRWLSQYV
What is the function of this protein?
Small GTPase component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.  Vtr-7/sar1 controls the coat assembly in a stepwise manner.  Activated sar1-GTP binds to membranes first and recruits the sec23/24 complex.  These sec23/24-sar1 prebudding intermediates are then collected by the sec13/31 complex as subunits polymerize to form coated transport vesicles.  Conversion to sar1-GDP triggers coat release and recycles COPII subunits (By similarity).
What are the official names of this protein?
Small COPII coat GTPase sar1, Vesicle transport protein 7.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. SAR1 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NIFW_RHORT
Sequence: MSRFLEDLRSLSSAEEFFSFLGVEFNPKVVQVNRLHILKKYQTYLKACDAEENGESVSRETHKRCLERAYADFLTSDARSEKLFKVFQSEAGKAFVGLDAILPLAAAERSESKVNSSAEA
What is the function of this protein?
May protect the nitrogenase Fe-Mo protein from oxidative damage.
What are the official names of this protein?
Nitrogenase-stabilizing/protective protein NifW.
What is the protein family that this protein belongs to?
Belongs to the NifW family.
Protein: TRM10_YEAST
Sequence: MSNDEINQNEEKVKRTPPLPPVPEGMSKKQWKKMCKRQRWEENKAKYNAERRVKKKRLRHERSAKIQEYIDRGEEVPQELIREPRINVNQTDSGIEIILDCSFDELMNDKEIVSLSNQVTRAYSANRRANHFAEIKVAPFDKRLKQRFETTLKNTNYENWNHFKFLPDDKIMFGDEHISKDKIVYLTADTEEKLEKLEPGMRYIVGGIVDKNRYKELCLKKAQKMGIPTRRLPIDEYINLEGRRVLTTTHVVQLMLKYFDDHNWKNAFESVLPPRKLDAEAKSASSSPAPKDT
What is the function of this protein?
S-adenosyl-L-methionine-dependent guanine N(1)-methyltransferase that catalyzes the formation of N(1)-methylguanine at position 9 (m1G9) in cytoplasmic tRNAs.
What are the official names of this protein?
tRNA (guanine(9)-N1)-methyltransferase, tRNA methyltransferase 10, tRNA(m1G9)-methyltransferase, tRNA(m1G9)MTase.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. TRM10 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SFSA_SHEPC
Sequence: MQFEPALQQGRLVKRYKRFLADIKLADGSEMTIHCPNTGSMRNCLFPGEAVWFSTSANPKRKYAYTWELMGTPNGGFIGIHSGSANALAEEAIHSGIIKELTGYDTLSREVKYGDENSRIDILLQGAQKPDCYIEVKSCTLLEDGQGFFPDAVSLRGQKHLRELMHMANLGHRAVLLFVVQHSEIFSVAPAAHIDHEYANLLKKATLSGVEVLAYRCEMSPTEIRLAQACPVRV
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: COAX_AZOPC
Sequence: MYIVIDQGNTILKIGLFEGKAVIKTFQTKEVKQEWFYSILKTYQPQAGILCSTREVSESLLSLLRESLSYFYEFKNNLPLPLSIDYQTPRTLGTDRLAAAVGAWYQKLNNNLLIIDIGTAITIDFVNRKGIYKGGNISLGPAMRLNALHYFTNSLPLISENGNIPIRGYDTETAIRSGVMEGIVHELGSYIEEYEKKENALTFLTGGNTIYFEKRLKGTLFVDKHLVLKGLNEILIYQKKFFKSK
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4062_CROS8
Sequence: MLKSVHQKVARRTGPLLAWLKLLWVRIDEDHMTTLAGNLAYVSLLSLVPFVAVIFALFAAFPMFSDVSVQLRHFVFANFMPATGDIIQRYIEQFVANSSKMTAVGALGLIVTSLLLMYAIDSALNTIWRSTRQRPKVYSFAVYWMILTLGPLLAGASLVISSYLLSLRWASGFNTMIDDVLRIFPLLLSWLSFWLLYSVVPTTRVPARDALIGSLVAALLFELGKKGFALYITMFPSYQLIYGVLAVIPILFLWVYWTWCIVLLGAEITVTLGDYRKLRQAAREEAESV
What are the official names of this protein?
UPF0761 membrane protein ESA_04062.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUOC_GEOMG
Sequence: MAETNRAVIKLREKFSASVLDVKEFRGEVTVTVKREDIVEICNFLKSSLAYNLCTDVTAVDYLGKQEPRFMVVYNLYSIPNKDRLRVKAGVPEAGCSIDTVSCVWSAANWLEREVYDLMGVVFNNHPDLRRILMTDDWVGHPLRKDYPLQGPGREPYKGRLS
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NIA2_ARATH
Sequence: MAASVDNRQYARLEPGLNGVVRSYKPPVPGRSDSPKAHQNQTTNQTVFLKPAKVHDDDEDVSSEDENETHNSNAVYYKEMIRKSNAELEPSVLDPRDEYTADSWIERNPSMVRLTGKHPFNSEAPLNRLMHHGFITPVPLHYVRNHGHVPKAQWAEWTVEVTGFVKRPMKFTMDQLVSEFAYREFAATLVCAGNRRKEQNMVKKSKGFNWGSAGVSTSVWRGVPLCDVLRRCGIFSRKGGALNVCFEGSEDLPGGAGTAGSKYGTSIKKEYAMDPSRDIILAYMQNGEYLTPDHGFPVRIIIPGFIGGRMVKWLKRIIVTTKESDNFYHFKDNRVLPSLVDAELADEEGWWYKPEYIINELNINSVITTPCHEEILPINAFTTQRPYTLKGYAYSGGGKKVTRVEVTVDGGETWNVCALDHQEKPNKYGKFWCWCFWSLEVEVLDLLSAKEIAVRAWDETLNTQPEKMIWNLMGMMNNCWFRVKTNVCKPHKGEIGIVFEHPTLPGNESGGWMAKERHLEKSADAPPSLKKSVSTPFMNTTAKMYSMSEVKKHNSADSCWIIVHGHIYDCTRFLMDHPGGSDSILINAGTDCTEEFEAIHSDKAKKMLEDYRIGELITTGYSSDSSSPNNSVHGSSAVFSLLAPIGEATPVRNLALVNPRAKVPVQLVEKTSISHDVRKFRFALPVEDMVLGLPVGKHIFLCATINDKLCLRAYTPSSTVDVVGYFELVVKIYFGGVHPRFPNGGLMSQYLDSLPIGSTLEIKGPLGHVEYLGKGSFTVHGKPKFADKLAMLAGGTGITPVYQIIQAILKDPEDETEMYVIYANRTEEDILLREELDGWAEQYPDRLKVWYVVESAKEGWAYSTGFISEAIMREHIPDGLDGSALAMACGPPPMIQFAVQPNLEKMQYNIKEDFLIF
What is the function of this protein?
Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.
What are the official names of this protein?
Nitrate reductase [NADH] 2, NR2.
What is the protein family that this protein belongs to?
Belongs to the nitrate reductase family.
Protein: SYD_STRPI
Sequence: MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREGIMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIVLNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEFIDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKCFRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRMKYDDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDIDKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTSIQAELTTALSLEDKDLVLFVADTLEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQEETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSAEEANDQFGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKASDPMTQAPSTVALKQLEELSLQVEEDETSKTN
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGB_PSEP1
Sequence: MSAQDFLVELGTEELPPKALTSLGEAFLAGIEKGLQAAGLNYTGKQVYAAPRRLAVLIRQLDVQQPDRSINIDGPPLQAAFNAEGEPTQAALGFAKKCGVELAEIDQSGPKLRFSQHIPGKATTDLLPTIVEDSLNDLPIPKRMRWAASREEFVRPTQWLVMLLGDQVVDCTILSQKAGRESRGHRFHHPETVVITTPANYVEDLRKAHVLADFAERRELISKRTAELAMQQEGTAIVPPALLDEVTALVEWPVPLVCSFEERFLEVPQEALITTMQDNQKYFCLLDSEGKLLPRFITVANIESRDPKQIVQGNEKVVRPRLTDAEFFFKQDKKQPLETFNERLKNVVFQAQLGTVYDKAERVSKLAAFVAPLIGGDAQRAGRAGLLSKCDLATEMVGEFPEMQGVAGYYYALNDGEPEDVALALNEQYMPRGAGAELPQTLTGAAVAIADKLDTLVGIFGIGMLPTGSKDPYALRRAALGVLRILIEKQLDLDLTGAVEFAVKQFGAKVKAPGLADQVLEFIFDRLRARYEDEGIDVATYLSVRALQPGSALDFDQRVQAVQAFRKLPEAEALAAVNKRVSNLLSKAEGAIAEQVEPKYFDNANEFSLYSAIQQADQAVQPMAAARQYSESLARLAALRDPVDAFFEAVMVNAEDAKVRANRYALLSRLRGLFLGVADISLLG
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUB_STAA9
Sequence: MYNGILPVYKERGLTSHDVVFKLRKILKTKKIGHTGTLDPEVAGVLPVCIGNATRVSDYVMDMGKAYEATVSIGRSTTTEDQTGDTLETKGVHSADFNKDDIDRLLENFKGVIEQIPPMYSSVKVNGKKLYEYARNNETVERPKRKVNIKDIGRISELDFKENECHFKIRVICGKGTYIRTLATDIGVKLGFPAHMSKLTRIESGGFVLKDSLTLEQIKELHEQDSLQNKLFPLEYGLKGLPSIKIKDSHIKKRILNGQKFNKNEFDNKIKDQIVFIDDDSEKVLAIYMVHPTKESEIKPKKVFN
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: ISPD_PARXL
Sequence: MTSRLFALIPCAGTGSRSGAAMPKQYRTVAGRDMLHFSLAAFDACSEFAQTLVVIAPDDAHFDARRFGGLRFAVRRSGGASRQASVLNGLHALAEFGAHDDDWVLVHDAARPGITPALIRTLVGALKDDTVGGIMALPVADTLKRIDANSADGRIARTEARDGLWQAQTPQMFRIGMLRAAILRAQADGHDLTDEASAIEWLGHAPKLVQGSLRNFKVTYPEDFDLAEAILSRPAVS
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: PANC_HERAR
Sequence: MKIISCIEELRDHLRGQLRTAFVPTMGNLHDGHLSLMRLARKHGDPVVASIFVNRLQFGPNEDFDRYPRTFQADVEKLEKEGVYILFAPTEKDLYPEPQEFRVQPPNDLGNTLEGEFRPGFFSGVTTIVLKLFSCVQPSVAVFGKKDYQQLMIVRNMSKQFALPTEIIAAETYRAEDGLALSSRNMYLSAEERAEAPALFKSLNAVANEVRSGHLDIFQLERQAMADLSQRGWKPDYISIRKRSNLQPPSAGDMAQGEKLVVLAAAKLGATRLIDNLEI
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MPEG1_BOVIN
Sequence: MNSFRGAFLIWAVATWAETDTSWGATDEPGFQNCKNALKLPVLPVLPGGGWDNLRNVDTGRVMELAYSHCRTTEDGQYIVPDEIFTIPQKQSNLEMNSKILESWVNYQSSTSNSINMELSLFSKVNGKFSLEFQRIKTLQVKDQAVTTQVQVRNLVYTVKINPDAELSLGFKKALMDISEQLENNQTRMATYLAELLVLNYGTHVITSVDAGAALIQEDHIRSSFLQDSQSSRSAVTASAGITFLNIVNFKFEENYTSQNTFTKSYLSNRTNSRVQSFGGLPFYPGITLQAWQQGVSNHLVAMDRAGLPLYFFINPERLPDLPGPLVRKLSKTVEAAVRRYYAVNTYPGCTDLSSPNFNFQANTDDGSCEGKMTNFSFGGVYQECTQFSGNEVVQLCQNLEQKNPLTGSVSCPSGYSPVQLLTQTHEEGYNHLECSRKCTLYIFCKTVCEDVFRVARAEFRAFWCAASGQVSENSGLLFGGLFSGKSINPLTNAQSCPAGYFQLKLFENLKVCASLDYELGYRFSIPFGGFFSCAAGNPLVDSATSKDLGAPSLRKCPGGFSQHLALISDGCQVSYCVKAGLFTGGSLPPVRLPPYTRPPLMSQVATNTVLVTNHETASSWIKDPQTHQWRLGEPLELRRAMRVVHGDGEGLSGGAAAGLTLGVTIALAGVVALAIYGARKSRKKGYQALQDEKQSLAAGAAVNGDALDQEQAQNPA
What is the function of this protein?
Plays a key role in the innate immune response following bacterial infection by polymerizing and inserting into the bacterial surface to form pores (By similarity).  By breaching the surface of phagocytosed bacteria, allows antimicrobial effectors to enter the bacterial periplasmic space and degrade bacterial proteins such as superoxide dismutase sodC which contributes to bacterial virulence (By similarity).  Shows antibacterial activity against a wide spectrum of Gram-positive, Gram-negative and acid-fast bacteria (By similarity).  Reduces the viability of the intracytosolic pathogen L. monocytogenes by inhibiting acidification of the phagocytic vacuole of host cells which restricts bacterial translocation from the vacuole to the cytosol (By similarity).  Required for the antibacterial activity of reactive oxygen species and nitric oxide (By similarity).
What are the official names of this protein?
Macrophage-expressed gene 1 protein, Macrophage gene 1 protein, Mpg-1, Perforin-2, P-2.
What is the protein family that this protein belongs to?
Belongs to the MPEG1 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Note=Bacterial infection induces translocation of the cytoplasmic vesicles to bacterium-containing phagocytic vesicles and fusing of the vesicles.
Protein: EFTS_CORDI
Sequence: MANYTAADVKKLREITGSGMLDCKKALEETNGDFDKAVEVLRIKGAKDVGKRAERNATEGLIAVSGNTMVEINSETDFVAKNAEFKEFAQKVADAAAAVKANTPEELAAADLDGKTAADAIQELSAKIGEKLELRRAITLEGEKLSVYLHQRSADLPPAVGVLVAYTGEGEAAQAAAHAAAMQVAALKAQYLTREDVPAEVIEKERSIAEQITREEGKPEKAIPKIVEGRLNGFYKDVCLVEQASVADSKKTVKQVMDEAGVTLTGFARYEVGQH
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAX_ACIC1
Sequence: MLLVIDIGNTHTVLGLFSGDTLVDHWRVATDARRTADELGFLIRGLLGQARRADGITGVSCCSTVPAALREVRTMSARWFPDAPLVVVEPGIRTGVPVLYDNPREVGADRIVNTLAAFTLHGGPAIVVDFGTSTNFDVVSARGEFLGGVLAPGIDISIDALASRAAQLVKVQVAKPRSVIGKNTVEALQAGIVYGFAAQVDGIVTRIAEQLPSRPVVIATGGLAPVVLDECRTVDVHDPWLTLTGLRLIFERNVPE
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P78_NPVAC
Sequence: MTNRRYESVQSYLFNNRNNKIDAHQFFERVDTAEAQIIKNNIYDNTVVLNRDVLLNILKLANDVFDNKAYMYVDDSEVSRHYNAVVKMKRLVIGVRDPSLRQSLYNTIAYIERLLNIGTVNDSEITMLIADFYDLYSNYNIELPPPQALPRSRRPSVVQPAAPAPVPTIVREQTKPEQIIPAAPPPPPSPVPNIPAPPPPPPPSMSELPPAPPMPTEPQPAAPLDDRQQLLEAIRNEKNRTRLRPVKPKTAPETSTIVEVPTVLPKETFEPKPPSASPPPPPPPPPPPAPPAPPPMVDLSSAPPPPPLVDLPSEMLPPPAPSLSNVLSELKSGTVRLKPAQKRPQSEIIPKSSTTNLIADVLADTINRRRVAMAKSSSEATSNDEGWDDDDNRPNKANTPDVKYVQALFNVFTSSQLYTNDSDERNTKAHNILNDVEPLLQNKTQTNIDKARLLLQDLASFVALSENPLDSPAIGSEKQPLFETNRNLFYKSIEDLIFKFRYKDAENHLIFALTYHPKDYKFNELLKYVQQLSVNQQRTESSA
What is the function of this protein?
Plays a role in the transport of the nucleocapsids from the cytoplasm toward the host nucleus together with the host actin-polymerizing Arp2/3 complex.
What are the official names of this protein?
Protein P78/83.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: RS19_ANAMF
Sequence: MSRSIKKPPFCAPHVLRLANRAIASNRNAIINIHSRSSVILHKFIGLTFGVHNGRTYVPVKVTDNIVGRKFGEFSPTRRFLGHAGDKKVSRKG
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: SYGB_KLEP3
Sequence: MSENTFLVEIGTEELPPKALRSLAESFAANVTAELDNAGLAHGKVEWFAAPRRLALKVANLAAAQADREVEKRGPAIAQAFDAEGKPSKAAEGWARGCGITVDQAERLTTDKGEWLLYRAHVKGESTEALLPNMIASSLAKLPIPKLMRWGASDVHFVRPVHTVTLLLGDKVIPATILGIPSDRVIRGHRFMGEPEFTIDHADQYPQILLERGKVIADYEQRKAKIKADAEEAARKIGGQADLSESLLEEVTSLVEWPVVLTAKFEEKFLGVPSEALVYTMKGDQKYFPVYDNAGKLLPNFIFVANIESKDPQQIISGNEKVVRPRLADAEFFFNTDRKKRLEDNLPRLETVLFQQQLGTLRDKTDRIQALAGWIAGQIGADVNHATRAGLLSKCDLMTNMVFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDALPSNPVACAVAIADKMDTLAGIFGIGQHPKGDKDPFALRRAALGVLRIIVEKNLNLDLQTLTEEAVRLYGEKLTNANVVDDVIDFMLGRFRAWYQDEGYGVDTIQAVLARRPTRPADFDARMKAVSHFRTLEESSALAAANKRVSNILAKSDETLNDIVHASVLKEAAEIKLAGNLVVLRDKLQPYFAAGRYQDALIELAALREPVDEFFENVMVNAEDKDVRINRLTLLSKLRELFLQVADISLLQ
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.