PharMolix/UniProtQA huggingface dataset:
Protein: SURE_MARSD
Sequence: MNILLTNDDGIQAVGLRALYHGLKRAGMNVQVVAPVAEQSAVGHAVSLSSPLRVKKFEEDGFTGLGVYGTPVDCVKLGLTTLLETKPDIVVSGINSGANVGVDILYSGTVSAATEGALMGYPAMAVSYDSFKPEELTDQGDYCAELLKKIPWDSLGDKTVVNLNFPAVPVKDAEELKICRHTRVSWQDWYEAREDPRGHKYYWLNGVMPKEKISPGTDRDLLTKGHITMTPLHFDFTDREAIATLEQSFGI
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEPE_SALPC
Sequence: MELLLLSNSTLPGKAWLEHALPLIANQLNGRRSAVFIPFAGVTQTWDEYTDKTAEVLAPLGVNVTGIHRVADPLAAIEKAEIIIVGGGNTFQLLKESRERGLLAPMADRVKRGALYIGWSAGANLACPAIRTTNDMPIVDPNGFDALDLFPLQINPHFTNALPEGHKGETREQRIRELLVVAPELTVIGLPEGNWIQVSNGQAVLGGPNTTWVFKAGEEAVALEAGHRF
What is the function of this protein?
Hydrolyzes dipeptides containing N-terminal aspartate residues.  May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids.
What are the official names of this protein?
Peptidase E, Alpha-aspartyl dipeptidase, Asp-specific dipeptidase, Dipeptidase E.
What is the protein family that this protein belongs to?
Belongs to the peptidase S51 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2671_BORPD
Sequence: MESRLLDTLVCPVCKGRLDFDRARAELLCRADRLAYPVRDGIPVMLESEARQLDAAPADTA
What are the official names of this protein?
UPF0434 protein Bpet2671.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: DCUP_SACEN
Sequence: MTNSAPVTPRRDLADAPLLAAARGETPRHTPVWFMRQAGRSLPEYRKVREGIPMLQSCLTPDLVCEITAQPVRRHGVDAAILFSDIVLPLHAAGVGLDIVAGTGPVVAEPVRTAADVAALPSLAPEQVSKVGDAVGLLLDELGSTPLIGFAGAPFTLASYLVEGGPSRNHERTKALMHSEPATWHALLEKLADTTLTFLRTQLAAGVDAIQLFDSWAGALSLRDYREFVLPHSRRIFEGVAETPGAAGVPKIHFGVGTGELLGAMRSAGADVVGVDWRVPLDTAAQRLREAGPDQGAPVVQGNLDPAVLFAGWEAVEREVRRILAEGRAAGGHIFNLGHGVLPSTDPGVLTRVVELVHAESAR
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR9_YERPE
Sequence: MQQRRPIRRALLSVSDKAGIIEFAQALSQRGIELLSTGGTARLLADAGLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDGIMAQHGIQPIDIVVVNLYPFAQTVARPDCSLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYPAIITELDNNDGSLTYPTRFNLAIKAFEHTAAYDSMIANYFGTLVPPYHGDTEQPSGHFPRTLNLNYIKKQDMRYGENSHQQAAFYIEEDVKEASVATAQQLQGKALSYNNIADTDAALECVKEFSEPACVIVKHANPCGVAIGDSILAAYERAYQTDPTSAFGGIIAFNRELDAATASAIISRQFVEVIIAPTVSSDALALLAAKQNVRVLTCGQWQARSAGLDFKRVNGGLLVQERDLGMVTAADLRVVSKRQPTEQELRDALFCWKVAKFVKSNAIVYARDNMTIGIGAGQMSRVYSAKIAGIKAADEGLEVAGSAMASDAFFPFRDGIDAAAAVGITCVIQPGGSIRDDEVIAAADEHSIAMIFTDMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: PDXJ_BACFR
Sequence: MTKLSVNINKVATLRNARGGNVPNVVKVALDCESFGADGITVHPRPDERHIRRSDVYDLRPLLRTEFNIEGYPSPEFIDLVLKVKPHQVTLVPDDPSQITSNSGWDTKVNFDFLTEVLDEFNGAGIRTSVFVAPDAEMIEYAAKAGADRVELYTEPYATAYPKDPAAAVAPFVEAAKAARRLGIGLNAGHDLSLLNLNYFYKNIPWLDEVSIGHALISDALYLGLERTIQEYKNCLR
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YJGA_ECOSM
Sequence: MTKQPEDWLDDVPGDDIEDEDDEIIWVSKSEIKRDAEELKRLGAEIVDLGKNALDKIPLDADLRAAIELAQRIKMEGRRRQLQLIGKMLRQRDVEPIRQALDKLKNRHNQQVVLFHKLENLRDRLIDQGDDAIAEVLNLWPDADRQQLRTLIRNAKKEKEGNKPPKSARQIFQYLRELAENEG
What are the official names of this protein?
UPF0307 protein YjgA.
What is the protein family that this protein belongs to?
Belongs to the UPF0307 family.
Protein: ZAPC_VIBCH
Sequence: MLKPSDKWSWYFSDSEGYLMLNLGDDMLFRTNLSRNLLVDCAFIENPFTVDDASDFQLYKEHIACLPLSEPRKAELALYCVAAKRFHKPVQPKSWFFDVQGTGYTPQQGQLISLRNSLNSGIFIALEVGENATLCAYSDLVSFALNGSKTLEFGQVIKVMHDRMSDVNTLLYTPQMAMVS
What is the function of this protein?
Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ.  Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
What are the official names of this protein?
Cell division protein ZapC.
What is the protein family that this protein belongs to?
Belongs to the ZapC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MED11_CANAL
Sequence: MSSLDNDKTENFIQERLDSLHEIDCKVVTLLDQFSSIFQSFYTKSKEDFSQQTSDIYSTLSKVAIDLRKEIKIMDDNIGAYDKNDDNVMILPISNVDQKNTKLGRKRLDLELAELKRLISDEKQVETLENESNNEIQPKTESDTNQVETNENGNDINNKESEDIEMKE
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 11, Mediator complex subunit 11.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 11 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MNTH_ECOLI
Sequence: MTNYRVESSSGRAARKMRLALMGPAFIAAIGYIDPGNFATNIQAGASFGYQLLWVVVWANLMAMLIQILSAKLGIATGKNLAEQIRDHYPRPVVWFYWVQAEIIAMATDLAEFIGAAIGFKLILGVSLLQGAVLTGIATFLILMLQRRGQKPLEKVIGGLLLFVAAAYIVELIFSQPNLAQLGKGMVIPSLPTSEAVFLAAGVLGATIMPHVIYLHSSLTQHLHGGSRQQRYSATKWDVAIAMTIAGFVNLAMMATAAAAFHFSGHTGVADLDEAYLTLQPLLSHAAATVFGLSLVAAGLSSTVVGTLAGQVVMQGFIRFHIPLWVRRTVTMLPSFIVILMGLDPTRILVMSQVLLSFGIALALVPLLIFTSDSKLMGDLVNSKRVKQTGWVIVVLVVALNIWLLVGTALGL
What is the function of this protein?
H(+)-stimulated, divalent metal cation uptake system.  Involved in manganese and iron uptake.  Can also transport cadmium, cobalt, zinc and to a lesser extent nickel and copper.  Involved in response to reactive oxygen.
What are the official names of this protein?
Divalent metal cation transporter MntH.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RUVC_SALAI
Sequence: MRVLGIDPGLTRCGVGVVEGVPGRPCTLIAYHVVRTDPDDELPLRLLHLDRSLTALVAEHRPDGVAVERVFSQHNVRTVMGTAQASGVAVLAGARAGIPVQTYTPSEVKAAVTGSGQADKAQMTAMVTRLLRLSEPPRPADAADALALAICHVWRGGTRSRLAAAADRARRGGGR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: GUF1_PHYPA
Sequence: MPSIRAPLALTSFLLSLSGKPSTCVRSGLAANSRPWFGSIAGRNRVLANAPWWGGKAELSTDNSVVSGGKEENVDLKQYPPHLIRNFSIIAHVDHGKSTLADRLLELTGTIRKGHGQPQFLDKLQVERERGITVKAQTATMFYNYRSKKTGGANERFLLNLIDTPGHVDFSYEVSRSLAACQGVLLLVDAAQGVQAQTVANFYLAFESDLAIIPVINKIDQINADPEGVKSQLKQIFDIDPESVLLTSAKTGLGLENILPAVIERIPQPKGLVDASLRMLLLDSYYDEYRGVICHVAVVDGVLKRGDKIESAATRQSYEIMEVGILYPELTNTGILLTGQVGYVVTGMRSTKEARIGDTLFHTRSVVEPLPGFKPARHMVFAGVYPADGSDYEALSSAVERLTCNDASVSIAKETSGALGIGFRCGFLGLLHMDVFHQRLEQEHGAQVITTTPTVPYIFEYSDGSKLTIQNPAALPSNPKSRLVACYEPTVMATIITPSEYVGSLMTLCSERRGQQTEYSFIDGQRAMLKYRMPLREVVIDFYNELKSITSGYASFDYEEAPYQESDLVKLDILLNGQPVDALASICHRSKAHYVGRELCEKLKKVLDRQMFEVAIQAAIGAKVVARETLPALRKNVLAKCYGGDVSRKRKLLEKQKEGKKRMKRVGNVDIPQEAFHSLLKTGN
What is the function of this protein?
Promotes mitochondrial protein synthesis.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Binds to mitochondrial ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Translation factor GUF1 homolog, mitochondrial, Elongation factor 4 homolog, EF-4, GTPase GUF1 homolog, Ribosomal back-translocase.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: INT3_PONAB
Sequence: MELQKGKGAAAAAAAASGAAGGGGGGAGAGAPGGGRLLLSTSLDAKDELEERLERCMSIVTSMTAGVSEREANDALNAYVCKGLPQHEEICLGLFTLILTEPAQAQKCYRDLALVSRDGMNIVLNKINQILMEKYLKLQDTCRTQLVWLVRELVKSGVLGADGVCMTFMKQIAGGDVTAKNIWLAESVLDILTEQREWVLKSSILIAMAVYTYLRLIVDHHGTAQLQALRQKEVDFCISLLRERFMECLMIGRDLVRLLQNVARIPEFELLWKDIIHNPQALSPQFTGILQLLQSRTSRKFLACRLTPDMETKLLFMTSRVRFGQQKRYQDWFQRQYLSTPDSQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTACTSNVAASNAKLALFYDWLFFSPDKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPNFYPPLEGHVRQGVFSSLNHIVEKRVLAHLAPLFDNPKLDKELRAMLREKFPEFCSSPSPPVEVKIEEPVSMEMDNHMSDKDESCYDNAEAAFSDDEEDLNSKGKKREFRFHPIKETVVEEPVDITPYLDQLDESLRDKVLQLQKGSDTEAQCEVMQEIVDQVLEEDFDSEQLSVLASCLQELFKAHFRGEVLPEEITEESLEESVGKPLYLIFRNLCQMQEDNSSFSLLLDLLSELYQKQPKIGYHLLYYLRASKAAAGKMNLYESFAQATQLGDLHTCLMMDMKACQEDDVRLLCHLTPSIYTEFPDETLRSGELLNMIVAVIDSAQLQELVCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYCAWQLFLAHNIPLETIIPILQHLKYKEHPEALSCLLLQLRREKPSEEMVKMVLSRPCHPDDQFTTSILRHWCMKHDELLAERIKSLLIKNNSLPRKRQSLRSSSSKLAQLTLEQILEHLDNLRLNLTNTKQNFFSQTPILQALQHVQASCDEAHKMKFSDLFSLAEEYEDSSTKPPKSRRKAALSSPRSRKNATQPPNAEEESGSSSASEEEDTKPKPTKRKRRGSSAVGSDSD
What is the function of this protein?
Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint.  The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability.  The SOSS complex is required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.  In the SOSS complex, it is required for the assembly of the complex and for stabilization of the complex at DNA damage sites.
What are the official names of this protein?
Integrator complex subunit 3, Int3, SOSS complex subunit A, Sensor of single-strand DNA complex subunit A, SOSS-A, Sensor of ssDNA subunit A.
What is the protein family that this protein belongs to?
Belongs to the Integrator subunit 3 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Localizes to nuclear foci following DNA damage.
Protein: CRIS2_HUMAN
Sequence: MALLPVLFLVTVLLPSLPAEGKDPAFTALLTTQLQVQREIVNKHNELRKAVSPPASNMLKMEWSREVTTNAQRWANKCTLQHSDPEDRKTSTRCGENLYMSSDPTSWSSAIQSWYDEILDFVYGVGPKSPNAVVGHYTQLVWYSTYQVGCGIAYCPNQDSLKYYYVCQYCPAGNNMNRKNTPYQQGTPCAGCPDDCDKGLCTNSCQYQDLLSNCDSLKNTAGCEHELLKEKCKATCLCENKIY
What is the function of this protein?
May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation.
What are the official names of this protein?
Cysteine-rich secretory protein 2, CRISP-2, Cancer/testis antigen 36, CT36, Testis-specific protein TPX-1.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Secreted.
Protein: AHPD_CORDI
Sequence: MSLDNLKSGLPEYAKDLKLNLGSLARSTELTEQQLWGTFLAVAAATRNEAVFSEISEEASEHLSEEAINAALGAASIMAMNNVAYRAKGWLGDDYAQVKMGLRMNIIAKPGVDKVDFELWSLAVSTVNGCEHCTIAHEKTVRSEGLTKEQIFEAVKIAATLQGVAQAIEIEASR
What is the function of this protein?
Antioxidant protein with alkyl hydroperoxidase activity.  Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
What are the official names of this protein?
Alkyl hydroperoxide reductase AhpD, Alkylhydroperoxidase AhpD.
What is the protein family that this protein belongs to?
Belongs to the AhpD family.
Protein: LUM_MOUSE
Sequence: MNVCAFSLALALVGSVSGQYYDYDIPLFMYGQISPNCAPECNCPHSYPTAMYCDDLKLKSVPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGKVFSKLKQLKKLHINYNNLTESVGPLPKSLQDLQLTNNKISKLGSFDGLVNLTFIYLQHNQLKEDAVSASLKGLKSLEYLDLSFNQMSKLPAGLPTSLLTLYLDNNKISNIPDEYFKRFTGLQYLRLSHNELADSGVPGNSFNISSLLELDLSYNKLKSIPTVNENLENYYLEVNELEKFDVKSFCKILGPLSYSKIKHLRLDGNPLTQSSLPPDMYECLRVANEITVN
What are the official names of this protein?
Lumican, Keratan sulfate proteoglycan lumican, KSPG lumican.
What is the protein family that this protein belongs to?
Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: MURD_SALRD
Sequence: MTPDEVRRTRATVVGGARSGRAAARLLAKVGGEVFLTEQDAPSDGAAAALDEAGVEYEFGGHTAEALDADVLVLSPGVPTQSNIVQQALRAGLDVYSEIEAASWFCDAPIVAITGTNGKTTTTSLTGHVFRTAFADTLGREAIVAGNIGYPFSDYVLETEPTDVVVLEVSSFQLDHVETFRPRVSVLLNITPDHLGRYDHDFEAYAQAKHNIFRNQGEGDVVVYNRDDDDVRNAAEEAAAEQGVRPMAITREGVPAAGAGFRDGRIVLRTDDEDDSLMPQDELALRGRHNMYNSLAAAVSARVMEVENDVIRESLSGFEGVPHRLEEVHTVDDVLYVNDSKATNVNAVWYALESFDRPIVLIAGGRDKGNDYTDLKPLVRDQVRAVVALGESAEKVERELGGEAPDHSRAETMEDALTQAQRAAQPGDVVLLSPACSSFDMYENYEERGDTFRRLVETLL
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRC_LAWIP
Sequence: MERPHPSSIPTTPGVYLYKDSQGRIIYVGKARNLRKRVLSYFRDGLVITPKTKAMMNHANLLETISTNTEKEALLLEASLIKKHRPRYNIVLRDDKQYLLFRIQKGIPFPRLEIVRQSYKDNAVYFGPFTSGTSVRDTWKFIHKIFPLRRCSDKVFNNRIRPCLYFYLQQCLAPCTEEVDPKDYAVLIQKVELFLSGKSKELVELLQKDMLYASEALEFEKAATLRDQIQAIKHTIERQSVVLPEGGDMDVIGIAVVNNGLALGFLFVREGKLLDGRTFFWPGLELDDGPELLGSFLSQFYSPISSIPPRIIVPWLPESTNNKDEISEDTFETLKYVLEDIRNSTVRIEVPKNIIESNLVDIAVTNAREAVQTKLGEPMSAKLAKVFHTDKPIFRIECVDVSHISGTNTRVGMVVFEDSQPLKNDYRIYSTTEDNSPFIKGDDYAALASWAKRRIQSGPPWADLVLIDGGKGQINAVQRVFNEHHLKDVFILAGIAKARNEEGRVDRRAGNIGDKIFVVGRMNPLTLKEGSPELLFLQYVRDTAHNFVLGKHRKARKNTALLGELLRIPGIGQATAKLLWSHFKTVEAMTCATIKDLEAIPGIGEAKARMLAERLQSLRNQ
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHSDA_XENLA
Sequence: MVTVLRLSSLCRANRASAFKSLLIRPVPCLSQDLHTVQTSQIHTSQNHHAASKAASLHWTSERALSVALLGLLPAAYLYPGAAVDYSLAAALTLHGHWGLGQVVTDYVHGDAKIKLANTSLFALSALTFAGLCYFNYHDVGICKAVAMLWSL
What is the function of this protein?
Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
What are the official names of this protein?
Succinate dehydrogenase [ubiquinone] cytochrome b small subunit A, mitochondrial, CybS-A, Succinate dehydrogenase complex subunit D-A, Succinate-ubiquinone oxidoreductase cytochrome b small subunit A, Succinate-ubiquinone reductase membrane anchor subunit A.
What is the protein family that this protein belongs to?
Belongs to the CybS family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MYOM2_HUMAN
Sequence: MSLVTVPFYQKRHRHFDQSYRNIQTRYLLDEYASKKRASTQASSQKSLSQRSSSQRASSQTSLGGTICRVCAKRVSTQEDEEQENRSRYQSLVAAYGEAKRQRFLSELAHLEEDVHLARSQARDKLDKYAIQQMMEDKLAWERHTFEERISRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKDPLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTASRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQRKEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDDVLYETETLPNLERGICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKVYDDMILAMSRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAKPKLIPASASAAGQ
What is the function of this protein?
Major component of the vertebrate myofibrillar M band.  Binds myosin, titin, and light meromyosin.  This binding is dose dependent.
What are the official names of this protein?
Myomesin-2, 165 kDa connectin-associated protein, 165 kDa titin-associated protein, M-protein, Myomesin family member 2.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere, M line.
Protein: EFTU_BUCAT
Sequence: MSKEKFQRLKPHINVGTIGHVDHGKTTLTAAITTVLSKKFGGSARAFDQIDNAPEEKARGITINTSHVEYDTEFRHYAHVDCPGHADYIKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRDLLTQYDFPGDDTPIIRGSALKALEGDPEWESKIIDLSKFLDSYIPEPKRAVDQPFLLPIEDVFSISGRGTVVTGRVEKGIIKVGEEVEIVGIKKTTKTTCTGVEMFRKLLDEGRAGENVGVLLRGTKRDEIERGQVLAKPGSIHPHTTFESEVYVLSKEEGGRHTPFFKGYRPQFYFRTTDVTGSIELPEGIEMVMPGDNIKMTVTLINPIAMADGLRFAIREGGRTVGAGVVSKVLL
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YR758_MIMIV
Sequence: MKLSFDSIVTKEPIRLAIIMENVIFDTRDEYGELHSESTMRKKYHEDLKPIPGAIEAFKNLNSITDLRNRKIFDVNIISTLSLTNQKSYINKIANVQKWFGDEALKKLIFCQDKSSIRTDILIDNSFKPQNFPDTNKFTLNTPYLQIRYGTDETNFYQIKSWTDNDYLDVIKKICIDLGLLVI
What are the official names of this protein?
Uncharacterized protein R758.
Protein: UPP_ECOLU
Sequence: MKIVEVKHPLVKHKLGLMREQDISTKRFRELASEVGSLLTYEATADLETEKVTIEGWNGPVEIDQIKGKKITVVPILRAGLGMMDGVLENVPSARISVVGMYRNEETLEPVPYFQKLVSNIDERMALIVDPMLATGGSVIATIDLLKKAGCSSIKVLVLVAAPEGIAALEKAHPDVELYTASIDQGLNEHGYIIPGLGDAGDKIFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: CCA_BURCJ
Sequence: MNIYAVGGAIRDELLGVPVQDRDYVVVGATPEQMTAQGFRPVGKDFPVFLHPQTQEEYALARTERKTAAGYHGFQFHYAPDVTLDEDLARRDLTINAMAREVSPEGTLVGPVIDPFDGQADLRARVFRHVSDAFVEDPVRILRIARFAARFADFTVADETLALMRRMVDAGEVDALVPERVWQEIARGLMEAKPSRMFAVLRDCGALARILPEVDALWGVPQRADYHPEVDTGVHVMMVVDYAAKQGYSLAVRFAALTHDLGKGTTPADVLPRHVGHESRSVELLKPLCERLRVPNECRDLALVVAREHGNLHRVMEMGAAALVRLFERSDALRKPARFAELLQACESDARGRLGLDAQPYPQAERLRVALAAARSVDAGAIARGIGSDTEKIKEAVHRARIQAVAQALAIGE
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: Y1006_METJA
Sequence: MAIQNGLRNRILFLVIFMKFYNREKELNYLKNYVQLEPNSILFVYGPKSSGKSTVMLRVIEELSKKDDLVFFYYDLREYATPTKEEFLEIFFEKGDKKYLLNRFEINLKIFKFGIEEKFDFDNIKLNDVFSKMKESINAVIKDGKKPILIIDELQKLKSIYFNGEGKGDKSLLNELFNLFVHLTKVRHLCHVICLTSDTLFIEEIYRNSTLENTSEYYLIDWLRKESIRNILKEEGFSEEEVDYCLKYLSLPYEISQLINNKKLGLSVEQTIKQWINIERDKILYLISTQKEFEMGKLIDALKLFENKIKVDIKEIIRDNLMDEVKFLIKNEILFYDVMNGIIKPTSVKKWYAIKEVIE
What are the official names of this protein?
Uncharacterized ATP-binding protein MJ1006.
What is the protein family that this protein belongs to?
Belongs to the archaeal ATPase family.
Protein: RF1_FRAT1
Sequence: MKDSIKAKLQSLIERHEEVSALLSEAGIISDQNKFRDLSKEYSHLEPIVKAFKKYTQALEDKQAAYEMLNEKDAELVEMAKEELKLANEAIEKLESELQIFLLPRDPNDDANVFLEIRAGTGGDEASIFSGDLFKMYSKYAEQRGWKIEVISASEGEHGGYKEIISRIYGDGVYSQLKFESGAHRVQRVPATESQGRIHTSACTVAVMPEADEVEGIDINPADIKVDTFRASGAGGQHVNKTDSAIRITHIPTGVVVECQDQRSQHKNRAAAMSMLKSKLLQAEIDKQQKEQSDTRKSLVGSGDRSERIRTYNYPQGRVTDHRINLTLYKLDEVMEGSLDSIIQPLVLEHQADLLATMSDE
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y907_HAEIN
Sequence: MENKAERYQKAVNITDVLEQSPFAKIIKKGLAINEINQKFNRIFPQEFHGKFRIGNMTDNSIFIETANAIVRQGILFRQTELLKLIQEEFPQVTGFEITINPGF
What are the official names of this protein?
Uncharacterized protein HI_0907.
Protein: YAIY_ECOLI
Sequence: MADFTLSKSLFSGKYRNASSTPGNIAYALFVLFCFWAGAQLLNLLVHAPGVYERLMQVQETGRPRVEIGLGVGTIFGLIPFLVGCLIFAVVALWLHWRHRRQ
What are the official names of this protein?
Inner membrane protein YaiY.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL29_ECOSM
Sequence: MKAKELREKSVEELNTELLNLLREQFNLRMQAASGQLQQSHLLKQVRRDVARVKTLLNEKAGA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.