PharMolix/UniProtQA huggingface dataset:
Protein: SYR_GEOSL
Sequence: MKDAVRDLVREALERSFADGTLASGHVPDIVVEKPALEEHGDFACTAAMLMAKAEKKAPRAIAEIIITHLNDRESLVESVEIAGPGFINFRMRTSAWCRVLRRIEREGGDYGKSEAGAGKKVQVEFVSANPTGPLHIGHGRGAAIGDTICRLLAAIGWDVTREFYYNDAGQQIANLALSVQARCLGVEPGGPLWPTDGYQGEYIKDVARSYLNRETVDAGDQHVTAAGDPHDVEAIRRFAVAYLRREQDQDLRAFDVGFDVYFLESSLYAEGRVDDVVQRIIAKGHAYEQDGALWLRTTEFGDDKDRVMRKSDGSYTYFVPDVAYHLNKWERGFIRVVNEQGADHHSTITRVRAGLQALDAGIPKGWPEYVLHQMVTVMRGGEEVKISKRAGSYVTLRDLVDEVGRDATRFFFLMRKPDSQLVFDIDLAKQQTLENPVYYVQYAHARICSIFENAADKGVVPPTVDQASLESLGTPEELTLVKLLSSFPEIVEGSALNFEPHRITYYLQELAGAFHSFYNKNRVITEDADLTGARLLLLHSTATVIRNGLGLLGVSAPEKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOLD_PSEA6
Sequence: MHELLKCDHLSKQYDDGKESVQILNNVNLSVNTSEQLAIIGSSGSGKSTLLHLLGALDQPTSGTVLFEQHDIFSFTSAEQAKFRNQSLGFVYQAHHLLPEFSALENVAMPRLIANEKREEAMHHAQNMLEKVGLAHRLTHRPSMLSGGERQRVAIARALVNQPKLVLADEPTGNLDTKTGEGIYQLLNELRDISQTSFIVVTHDIQLAKRLDRSLRLVNGQLSPQLD
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: EDC2_YEAST
Sequence: MGSETKHSAKVKIVTRESPPSAKEHMRPTKTQILVPPTQSLPNGKKPNFGKSTKQRREPRERTSKTGHEDDKATMVTVNIDAFLHDKAPKKKSCKYKKKKTRQYQDRAAASIDSKPHVAGHTAFAGASFTTDIPHEAALPKPSFV
What is the function of this protein?
mRNA-binding protein which stimulates mRNA decapping by DCP1 and DCP2.
What are the official names of this protein?
Enhancer of mRNA-decapping protein 2.
What is the protein family that this protein belongs to?
Belongs to the EDC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CYB_DREAL
Sequence: MALNLRKNHPLLKTINDSLIDLPTPSNISIWWNFGSLLGICLMVQIITGLLLATHYTADTSLAFSSVAHMCRNVQFGWLIRNLHANGASLFFICIYLHIGRGFYYGSYLNKETWNIGVILLLTLMATAFVGYVLPWGQMSFWGATVITNLFSAIPYIGQTLVEWAWGGFSVDNPTLTRFFALHFLLPFVITGLTLVHLTFLHETGSNNPLGIPSDCDKIPFHPYYSIKDILGFALMLITLATLALFSPNLLGDPENFTPANPLATPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASVLILFLIPLLHTSKQRSMTFRPLSQILFWILVTNLLILTWVGSQPVEHPFIIIGQLASFSYFMIILVLFPIAGVLENKLLNP
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: FUR_NEIGO
Sequence: MEKFSNIAQLKDSGLKVTGPRLKILDLFEKHAEEHLSAEDVYRILLEEGVEIGVATIYRVLTQFEQAGILQRHHFETGKAVYELDKGDHHDHIVCVKCGEVTEFHNPEIEALQDKIAEENGYRIVDHALYMYGVCSDCQAKGKR
What is the function of this protein?
Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.  Regulates the expression of the fbp protein.
What are the official names of this protein?
Ferric uptake regulation protein, Ferric uptake regulator.
What is the protein family that this protein belongs to?
Belongs to the Fur family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DJC14_BOVIN
Sequence: MAQKHPGEGGLCGAHHSGGASLRTLGPSVDPDILSFSGLRDSAGSAPNGTRCLTEHSSPKYTQPPNPAHWSDPSHGPPRGPGPPLAEEDPDQSEASSEESGVDQELSRENETGYQDDGNSSFLSIPSTCNCQGTPGIPEGPYSEGRDSSSSNFCHHCTSPALGEDEELEGEYDEEEPLKFPSDVSRVPSEKKPAPRRQRHRVPAKEDTREGGRRDPRSPGRHRLGRKRSQADKRRGLGLWGAEELCQLGQAGFWWLIELLVLVGEYVETCGHLIYACRQLKGSDLDLLRVWVGVWAGRLRGWAQVMFQFLSQGFCYGAGLFTRFLRLVGALLLLALALLLGCLQLGWRFLVGLSDRLGWRDKATWIFSWLASPTWQRCLILLRESRPWQQLVRIVQWGWLELPWVKQRTNRQANAPVAGGRYCQPEEEVARLLTMAGVPEDELNPFHVLGVEATASDVELKKAYRQLAVMVHPDKNHHPRAEEAFKVLRAAWDIVSNPERRKEYEMKRMAENELSRSVNEFLSKLQEAMNTMMCSRCQGKHRRFEMDREPKSARYCAECNRLHPAEEGDFWAESSMLGLKITYFALMDGKVYDITEWAGCQRVGISPDTHRVPYHISFGSRMPGTSGRQRATPDAPPADLQDFLSRIFQVPPGQMSNGNFFAAPQPGPGATAASKPNSTVPKGEAKPKRRKKVRRPFQR
What is the function of this protein?
Regulates the export of target proteins, such as DRD1, from the endoplasmic reticulum to the cell surface (By similarity).  Promotes cleavage of pestivirus polyprotein.
What are the official names of this protein?
DnaJ homolog subfamily C member 14, J domain protein interacting with viral protein, Jiv.
Protein: ASIP_MACMR
Sequence: MDVTRLLLATLLVFLCFFTAYSHPPPEEKLRDDRSLRSNSSVNLLDFPSVSIVALNKNSKQISRKEAEKKRSSKKEASMKKVARPRTPLSAPCVATRDSCKPPAPACCDPCASCQCRFFRSACSCRVLSLNC
What is the function of this protein?
Involved in the regulation of melanogenesis.  The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity).
What are the official names of this protein?
Agouti-signaling protein, ASP, Agouti switch protein.
What are the subcellular locations of this protein?
Secreted.
Protein: LFTR_YERP3
Sequence: MRVTQLSSQSFIFPSPELALREPNGLLALGGDLTAPRLLAAYQRGIFPWFNPGEMILWWSPDPRAVLFPEDLHISRSMRRFIRHCPYRFTLNHAFADVISACATERDEGTWIGRDVQQAYCQLHALGHAHSLEVWLENELVGGLYGVAVGAVFCGESMFSRADNASKSALMVFCHHFTQHGGELIDCQVLNAHTASLGAVEIPRNFFLQQLSQLQFSPLPAECWLPQSLNFSSAMQ
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYW_SYNY3
Sequence: MDKPRILSGVQPTGNLHLGNYLGAIRSWVEQQQHYDNFFCVVDLHAITVPHNPQTLAQDTLTIAALYLACGIDLQYSTIFVQSHVAAHSELAWLLNCVTPLNWLERMIQFKEKAVKQGENVSVGLLDYPVLMAADILLYDADKVPVGEDQKQHLELTRDIVIRINDKFGREDAPVLKLPEPLIRKEGARVMSLADGTKKMSKSDESELSRINLLDPPEMIKKKVKKCKTDPQRGLWFDDPERPECHNLLTLYTLLSNQTKEAVAQECAEMGWGQFKPLLTETAIAALEPIQAKYAEILADRGELDRIIQAGNAKASQTAQQTLARVRDALGFLAPPY
What is the function of this protein?
Catalyzes the attachment of tryptophan to tRNA(Trp).
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TFIIB_ASFP4
Sequence: MDALLKEIEKLSQPSLQKENNDVCDLCFMQMKKISNYQLLCEECGQLKDWFEPEYNEKFTVYSRLKIVGANSSYHQRDLDKANSSDYSSLQFHHILEELKSLNVKYMDAGQKPFPIQVLKETAHSYNQVQQHRVIRSITKLQILASILRSICLKLNIACTVADAARFTQLNTKGISRGMDLLRSLFVDNKITLNVDLNPIDSFINSTYNALQIKQIHQELQEENVYNLKEIVKSFILYADEKNIGVDLNRRTVVIATMYNVLRRAYYPIEIDTVVYQCKIRKNTITRALKMYEDYYSHFKSLYEQYHLNAAKKLI
What is the function of this protein?
Putative initation factor.
What are the official names of this protein?
Initiation factor TFIIB homolog, pC315R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus C315R family.
Protein: FTSK_ECOLI
Sequence: MSQEYIEDKEVTLTKLSSGRRLLEALLILIVLFAVWLMAALLSFNPSDPSWSQTAWHEPIHNLGGMPGAWLADTLFFIFGVMAYTIPVIIVGGCWFAWRHQSSDEYIDYFAVSLRIIGVLALILTSCGLAAINADDIWYFASGGVIGSLLSTTLQPLLHSSGGTIALLCVWAAGLTLFTGWSWVTIAEKLGGWILNILTFASNRTRRDDTWVDEDEYEDDEEYEDENHGKQHESRRARILRGALARRKRLAEKFINPMGRQTDAALFSGKRMDDDEEITYTARGVAADPDDVLFSGNRATQPEYDEYDPLLNGAPITEPVAVAAAATTATQSWAAPVEPVTQTPPVASVDVPPAQPTVAWQPVPGPQTGEPVIAPAPEGYPQQSQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTYQTEQTYQQPAAQEPLYQQPQPVEQQPVVEPEPVVEETKPARPPLYYFEEVEEKRAREREQLAAWYQPIPEPVKEPEPIKSSLKAPSVAAVPPVEAAAAVSPLASGVKKATLATGAAATVAAPVFSLANSGGPRPQVKEGIGPQLPRPKRIRVPTRRELASYGIKLPSQRAAEEKAREAQRNQYDSGDQYNDDEIDAMQQDELARQFAQTQQQRYGEQYQHDVPVNAEDADAAAEAELARQFAQTQQQRYSGEQPAGANPFSLDDFEFSPMKALLDDGPHEPLFTPIVEPVQQPQQPVAPQQQYQQPQQPVPPQPQYQQPQQPVAPQPQYQQPQQPVAPQQQYQQPQQPVAPQQQYQQPQQPVAPQPQDTLLHPLLMRNGDSRPLHKPTTPLPSLDLLTPPPSEVEPVDTFALEQMARLVEARLADFRIKADVVNYSPGPVITRFELNLAPGVKAARISNLSRDLARSLSTVAVRVVEVIPGKPYVGLELPNKKRQTVYLREVLDNAKFRDNPSPLTVVLGKDIAGEPVVADLAKMPHLLVAGTTGSGKSVGVNAMILSMLYKAQPEDVRFIMIDPKMLELSVYEGIPHLLTEVVTDMKDAANALRWCVNEMERRYKLMSALGVRNLAGYNEKIAEADRMMRPIPDPYWKPGDSMDAQHPVLKKEPYIVVLVDEFADLMMTVGKKVEELIARLAQKARAAGIHLVLATQRPSVDVITGLIKANIPTRIAFTVSSKIDSRTILDQAGAESLLGMGDMLYSGPNSTLPVRVHGAFVRDQEVHAVVQDWKARGRPQYVDGITSDSESEGGAGGFDGAEELDPLFDQAVQFVTEKRKASISGVQRQFRIGYNRAARIIEQMEAQGIVSEQGHNGNREVLAPPPFD
What is the function of this protein?
Essential cell division protein that coordinates cell division and chromosome segregation.  The N-terminus is involved in assembly of the cell-division machinery.  The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region.  Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination.  FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation.  FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.  Stoppage of translocation is accompanied by a reduction in ATPase activity.  Also stimulates topoisomerase 4 activity.  Required for the targeting of FtsQ, FtsL and FtsI to the septum.
What are the official names of this protein?
DNA translocase FtsK.
What is the protein family that this protein belongs to?
Belongs to the FtsK/SpoIIIE/SftA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Located at the septum. Colocalizes with FtsZ. ZipA, FtsZ and FtsA, but not FtsI and FtsQ are required to target it to the septum.
Protein: SYI_ECO24
Sequence: MSDYKSTLNLPETGFPMRGDLAKREPGMLARWTDDDLYGIIRAAKKGKKTFILHDGPPYANGSIHIGHSVNKILKDIIVKSKGLSGYDSPYVPGWDCHGLPIELKVEQEYGKPGEKFTAAEFRAKCREYAATQVDGQRKDFIRLGVLGDWSHPYLTMDFKTEANIIRALGKIIGNGHLHKGAKPVHWCVDCRSALAEAEVEYYDKTSPSIDVAFQAVDQDALKAKFAVSNVNGPISLVIWTTTPWTLPANRAISIAPDFDYALVQIDGQAVILAKDLVESVMQRIGVTDYTILGTVKGAELELLRFTHPFMGFDVPAILGDHVTLDAGTGAVHTAPGHGPDDYVIGQKYGLETANPVGPDGTYLPGTYPTLDGVNVFKANDIVVALLQEKGALLHVEKMQHSYPCCWRHKTPIIFRATPQWFVSMDQKGLRAQSLKEIKGVQWIPDWGQARIESMVANRPDWCISRQRTWGVPMSLFVHKDTEELHPRTLELMEEVAKRVEVDGIQAWWDLDAKEILGDEADQYVKVPDTLDVWFDSGSTHSSVVDVRPEFAGHAADMYLEGSDQHRGWFMSSLMISTAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVMNKLGADILRLWVASTDYTGEMAVSDEILKRAADSYRRIRNTARFLLANLNGFDPAKDMVKPEEMVVLDRWAVGCAKAAQEDILKAYEAYDFHEVVQRLMRFCSVEMGSFYLDIIKDRQYTAKADSVARRSCQTALYHIAEALVRWMAPILSFTADEVWGYLPGEREKYVFTGEWYEGLFGLADSEAMNDAFWDELLKVRGEVNKVIEQARADKKVGGSLEAAVTLYAEPELAAKLTALGDELRFVLLTSGATVADYNDAPADAQQSEVLKGLKVALSKAEGEKCPRCWHYTQDVGKVAEHAEICGRCVSNVAGDGEKRKFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_PASMU
Sequence: MKNIRNFSIIAHIDHGKSTLSDRLIQTCGGLSDREMEAQVLDSMDLERERGITIKAQSVTLNYKAKDGETYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAGQGVEAQTLANCYTAIEMNLEVVPILNKIDLPAADPERVAEEIEDIVGIDAMEAVRCSAKTGVGIEDVLEEIVHKIPAPEGDPNAPLQALIIDSWFDNYLGVVSLVRIKNGTLRKGDKIKVMSTGQSYNVDRLGIFTPKQVDTTILNCGEVGWVVCAIKDILGAPVGDTLTSHNNPASSVLPGFKKVKPQVYAGLFPISSDDYEAFRDALGKLSLNDASLFYEPENSTALGFGFRCGFLGLLHMEIIQERLEREYDLDLITTAPTVVYEVEKTDGEVIYVDSPSKLPPLNNITEIREPIAECNMLLPQTYLGNVITLCVEKRGVQTNMVYHGNQVALTYEIPMGEVVLDFFDRLKSTSRGYASLDYGFKRFQAADMVRVDIMINGERVDALALIVHKDNAPYRGRELVEKMRELIPRQQFDIAIQAAIGNHIIARSTVKQLRKNVLAKCYGGDVSRKKKLLQKQKEGKKRMKSLGNVEVPQEAFLAILHVGKDK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ATPG_GEOSL
Sequence: MASLKSIKKRIVSVKNTRQITKAMKMVSAAKLRRAQENVVAARPYAKKLGEVLQRLAKSQDESGSPLMQQRLSQKALLIVVTSDRGLCGGFNANICKAAERFIKEKKAEFAEISVTTVGRKGYEFLKNRQKIHKNYGNVLANLSYPAAALLAQEMIEGYIAEEYDEVYILFNAFKSVMSQDITLEKLLPIAPEAASTEEYAPEYIYEPSKGELLAELLPKHIEVQVFKALLESVASEHGARMTAMDSASKNATEMIGKLTLQYNRARQAAITTELMEIISGAESIKG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PLC_HALLA
Sequence: GCPLGFHQNRRSCYWFSTIKSSFAEAAGYCRYLESHLAIISNKDEDSFIRGYATRLGEAFNYWLGASDLNIEGRWLWEGQRRMNYTNWSPGQPDNAGGIEHCLELRRDLGNYLWNDYQCQKPSHFICEKERIPYTNSLHANLQQRDSLHANLQQR
What is the function of this protein?
May promote nucleation and/or growth of calcium carbonate crystals.  Binds to D-galactose and D-mannose/D-glucose.
What are the official names of this protein?
Perlucin.
Protein: LFTR_ECOSM
Sequence: MRLVQLSRHSIAFPSPEGALREPNGLLALGGDLSPARLLMAYQRGIFPWFSPGDPILWWSPDPRAVLWPESLHISRSMKRFHKRSPYRVTMNYAFGQVIEGCASDREEGTWITRGVVEAYHRLHELGHAHSIEVWREDELVGGMYGVAQGTLFCGESMFSRMENASKTALLVFCEEFIGHGGKLIDCQVLNDHTASLGACEIPRRDYLNYLNQMRLGRLPNNFWVPRCLFSPQE
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4078_BACAC
Sequence: MGFPKEGEKVQIHSYKHNGSIHRMWKETTILKGTQSLVIGANDRTVVTESDGRTWITREPAICYFHENYWFNVIGMLREEGVYYYCNLSSPFAYDSEALKYIDYDLDIKVYPDMTYTLLDEDEYEKHSQIMQYPPVIDTILKRNVAQLTQWIHQRKGPFAPDFVDMWYERYLMYRN
What are the official names of this protein?
UPF0374 protein BAMEG_4078.
What is the protein family that this protein belongs to?
Belongs to the UPF0374 family.
Protein: PHK2_LACPL
Sequence: MSEAIKSKTVDYSSDEYLKRVDEYWRAANYISVGQLYLLNNPLLREPLKATDVKVHPIGHWGTIAGQNFIYAHLNRAINKYGLNMFYIEGPGHGGQVMVSNSYLDGTYTETYPKITQDKAGMKRLFKQFSFPGGVASHADPKTPGSIHEGGELGYSILHGAGAVLDNPGLIAATVVGDGESETGPLATSWQVNKFLNPITDGTVLPILNLNGFKISNPTVLSRESHEELEDYFKGLGWDPHFVEGTDPAKMHKIMAEELDKVIEEIHAIRKNAKDNNDESRPKWPMIVFRAPKGWTGPKSWDGEPIEGSFRAHQIPIPVDRNHMEHADKLVDWLKSYKPEELFDENGTLKPEIAAIIPEGQARMAANPVTNGGKLTKDLITPNIDDYALDNKSHGKEDGSDMTELGKYIRDLIELNKDNKNFRGWGPDETLSNKLGAAFEDTKRQWMEPIHEPNDALLAPQGRIIDSMLSEHMDEGMLEAYNLTGRYGFFASYESFLRVVDSMLTQHFKWLRNSHEETPWRADVPSLNVIASSTAFQQDHNGYSHQDPGIISHLAEKKTEYVRAYLPGDANTLIATFDKAIQSKQLINLIIASKHPRPQWFTMDEAKRLVRDGLGVVDWASTDHGEEPDVVFATAGSEPTTESLAAVSILHARFPEMKIRFINVVDLLKLKKDDPRGLSDAEFDAFFTKDKPVIFAYHAYDDLVKTIFFDRHNHNLHVHGYREEGDITTPFDMRVRNELDRFHLVKAALLATPAYAEKGAHVIQEMNSILDKHHDYIRAEGTDIPEVENWKWTALK
What are the official names of this protein?
Probable phosphoketolase 2.
What is the protein family that this protein belongs to?
Belongs to the XFP family.
Protein: DAPB_SHEDO
Sequence: MTTKVRVAVVGASGRMGRVLIEAAKHQDVITLGAAIERQGSTLIGADAGELAGVGCVNVAICDSLDNVKDDFDVLIDFTSPDASMLHLEWCLRHKKPMVIGTTGFNHAQKEQISACAEQIPVVFSPNMSVGVNLMWKLLEVATAVMGQDTDIEIIEAHHRHKKDAPSGTALKMGEIIANTLGRDLEECAVYGREGITGARDRNTIGFSTIRAGDIVGEHTAMFADIGERIEITHKASSRMTYANGAMRAAFWLYDQNAGLYDMQQVLGLS
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPC_MACFA
Sequence: MVGYDPKPDGRNNTKLQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRRDPNAKYHGIFQASRQILQEEGLTAFWKGHIPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACTATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAMPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFWYEFFCNVFHCMNRTASQR
What is the function of this protein?
Mitochondrial transporter mediating uptake of thiamine diphosphate into mitochondria.  It is not clear if the antiporter activity is affected by the membrane potential or by the proton electrochemical gradient.
What are the official names of this protein?
Mitochondrial thiamine pyrophosphate carrier, Solute carrier family 25 member 19.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL17_CLONN
Sequence: MAQQRKLGLPTDHRRAMLRNLVTSFLKNGKVETTITRAKEARNMAEKMITLAKRGDLHARRQVLAYVTEKEVVDHLFAEIAPKYADRNGGYTRMYKMGPRRGDGAEVVILELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: YIDC_HAEI8
Sequence: MDSRRSLLVLALIFISFLVYQQWQLDKNPPVQTEQTTSITATSDVPASSPSNSQAIADSQTRGRIITLENDVFRLKIDTLGGDVISSELLKYDAELDSKTPFELLKDTKEHIYIAQSGLIGKNGIDTRSGRAQYQIEGDNFKLAEGQESLSVPLLFEKDGVTYQKIFVLKRGSYDLGVDYKIDNQSGQAIEVEPYGQLKHSIIESSGNVAMPTYTGGAYSSSETNYKKYSFADMQDNNLSIDTKAGWVAVLQHYFVSAWIPNQDVNNQLYTITDSKNNVASIGYRGPVVTIPAGSQETITSSLWTGPKLQNQMATVANNLDLTVDYGWAWFIAKPLFWLLTFIQGIVSNWGLAIICVTIVVKAILYPLTKAQYTSMAKMRILQPKMQEMRERFGDDRQRMSQEMMKLYKEEKVNPLGGCLPILLQMPIFIALYWTFLEAVELRHAPFFGWIQDLSAQDPYYILPILMGISMFLLQKMSPTPVTDPTQQKVMNFMPLVFMFFFLWFPSGLVLYWLVSNLITIAQQQLIYRGLEKKGLHSRKK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PLEK_MOUSE
Sequence: MEPKRIREGYLVKKGSVFNTWKPMWVVLLEDGIEFYKKKSDNSPKGMIPLKGSTLTSPCQDFGKRMFVLKITTTKQQDHFFQAAFLEERDAWVRDIKKAIKCIEGGQKFARKSTRRSIRLPETIDLGALYLSMKDPEKGIKELNLEKDKKVFNHCLTGSGVIDWLVSNKLVRNRQEGLMISASLLSEGYLQPAGDLSKNAADGIAENPFLDSPDAFYYFPDSGFFCEENSSDDDVILREEFRGVIIKQGCLLKQGHRRKNWKVRKFILREDPAYLHYYDPAGGEDPLGAVHLRGCVVTSVESSHDVKKSDEENLFEIITADEVHYYLQAATSKERTEWIKAIQVASRTGK
What is the function of this protein?
Major protein kinase C substrate of platelets.
What are the official names of this protein?
Pleckstrin.
Protein: DNAA_CALS4
Sequence: MYGDYRQIWERIVEVIKSELTPTSYNTWLVHIKPLAFAEDTLFLSTPNTFTKNIINGRYINIIYDAASKVTNRFIEIKILSEDEEEYREIKESIERENSSESTLLSTLNPKYTFDTFVVGNSNKLAHAACLAVAQSPAKAYNPLFIYGGVGLGKTHLMHAIGHFINKNHAGYKIMYVTSETFTNELVNSIKDDKNEEFRNKYRNIDVLLIDDIQFIANKERTQEEFFHTFNTLYEANKQIVISSDRPPKEIPTLEERLRSRFEWGLIADIQPPDYETRVAILKKKAQSENLNIPDEVLAYVAEKIQSNIRELEGALIRIVAFATLTKSNIDLELTKHALKDIVSNKTREITVKLIQEEVCKYYNIKLEDFRSRKRTKNIAYPRQIAMYLARELTDLSLPKIGEEFGKDHTTVIHAYEKISNEIKQDESLARQIEELKKRIKGY
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU3_CANGA
Sequence: MAVTKTIVVLPGDHVGQEITEEAIKVLNAIQECRPDKVNFKFDHHLIGGAAIDATGVPLPDEALEASKKADAVLLGAVGGPKWGTGAVRPEQGLLKIRKELQLYANLRPCNFASDSLLDLSPLKPEIARGTDFVVVRELVGGIYFGERKEDEGDGVAWDSEKYSVPEVQRITRMAAFMALQHNPPLPIWSLDKANVLASSRLWRKTVEETIKNEFPQLTVQHQLIDSAAMILVKNPTHLNGIIITNNMFGDIISDEASVIPGSLGLLPSASLASLPDKNTAFGLYEPCHGSAPDLPKGKVNPVATILSAAMMLKLSLDLFEEGEIIEQAVKKVLDSGIRTADLKGTNSTTEVGDAVAKAVRELLA
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, IMDH, Beta-IPM dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CINAL_THENN
Sequence: MKKAAIITVGSELLEGLILNRNAQFLCQELKNLGYRVIKVSTVGDHLEDIAEEVRSLLPEVHLLILTGGLGPTKDDLTREAVAKALNRKLLLDYNLKTKIEEKVKKYHSKIPSNIEKQALVIEGAKVIDNPVGSAPGQLLEVDGKKVILLPGPPKELIPMFESLKELLKTPHAFYQVVLKYYSIPEAVLEDLLKEILYSQDRVEVATMADHVEGVRLRLTTSAEHREFLDELVEKILEKTGEYLYGMNDEKMEEVVVRLLKENKKTLAVAESCTGGMLSSLVVNVPGASDVFIGGVVAYSNELKKSILGVKEDTLRKYGAVSEQCVQEMTEGLKKLTEADICVAISGIAGPSGGTPTKPVGTVFIDLFEQNHSTVRYNFSGDRNTIRTRSAMMALENLRKHLKERGRS
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.