PharMolix/UniProtQA huggingface dataset:
Protein: WDR48_AEDAE
Sequence: MLTHKNNQGGRKKMQVSFVIRDAEEKRHRNGVNALQLDTINGRLYSAGRDAIIRVWNSMQNNSQEPYIQSMEHHNDWVNDIVLCCGGRNLISASCDTTVKVWNAHKGFCMSTLRTHRDYVQALAYAKDREQVASAGLDKAIFLWDINTLTALTASNNTVTTSSITGSKDSIYSLAMNPSGTVIVCGSTENTLRIWDPRTCNKIAKLKGHAENVKALVVSEDGQHVISGSSDGKIKQWSIGQQRCVQTISVHSEGVWALLMTDNFSHVISGSRDKKIIMTDLRNPTNSVLICEERAPVLSLCYNYDQTGVWATTWNSDIRCWKLNPSEKLSFEVACIKGGAAIKKYHVLNDKRFMLTKDSEMNVAIYDVLKVKKVEDLGKVDYEEEIKKRSQKVYVPNWFTVDLKTGMPTIVLGQDEVDCFAAWVSAEAGLPEHAESGTDPKVNYGSLLLQALLEYWKPPPPHHHLQGVGSDLDSNGCDGDIRGNEYFSVPKHTPIIFSEVGGRNVCRLLVKDAVGETESALLSETVPSWVTNVVIERTIPKFIKLPFYLLAHPSMLKQDRSKKERLIANEFIQCRKVCEHVLEKVLGADLPASTGNSNSSQNNSQSDANSEGSQVPAEERIELLCNDVICDPNMDLRTVRHFIWKQSSDLTFHYRTKSN
What is the function of this protein?
Regulator of deubiquitinating complexes.  Activates deubiquitination by increasing the catalytic turnover without increasing the affinity of deubiquitinating enzymes for the substrate (By similarity).
What are the official names of this protein?
WD repeat-containing protein 48 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR48 family.
Protein: HSCA_BURMA
Sequence: MALLQISEPGMAPAPHQRRLAVGIDLGTTNSLVAAVRNSIPEALPDDAGRVLLPSVVRYLDKGGRRIGHAAKEEAAIDPRNTIVSVKRFMGRGKAEVEGAANAPYEFVDAPGMVQIRTVDGVKSPVEVSAEILATLRQRAEDTLGDDLVGAVITVPAYFDDAQRQATKDAARLAGLNVLRLLNEPTAAAIAYGLDNGAEGLYAVYDLGGGTFDLSILKLTKGVFEVLAAGGDSALGGDDFDHLLFEHVLAQAGLEVAALAPEDVRLLLDRVRGAKEALSAAPQARVDVKLSTGEKLAQTITRDTFAALVEPLVQRTLGPTRKALRDAQVSAADIKGVVLVGGATRMPVIRDAVAKYFGQPPLVNLDPDQVVALGAAIQADLLAGNRSGGDDWLLLDVIPLSLGVETMGGLVEKIIPRNSTIPVARAQEFTTFKDGQTAMAIHVVQGERELVSDCRSLARFELRGIPPMTAGAARIRVTYQVDADGLLSVFAREQHSGVEASVVVKPSYGLGDDDIARMLEDSFKTAEVDMRARALREAQVEAQRLVEATEAALVADGDLLDASERATVDALVASLRALAPGDDADAIDTATKALAEGTDEFAARRMDKSIKRALAGRKLDEI
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: SYP_CLONN
Sequence: MSKKKKFVEAITPMDEDFAKWYTDIVKKAELVDYASVKGCMIIRPYGYAIWENIQKYLDTKFKETGHENVYMPMFIPESLLQKEKDHVEGFAPEVAWVTQGGNDTLAERLCVRPTSETLFCDHYAKIIQSHNDLPKKYNQWCSVVRWEKTTRPFLRTTEFLWQEGHTAHATAEESAKETIDMLNVYANFCENVLAIPVIKGQKTEKEKFAGAKATYTIESLMHDGKALQSGTSHNFGDNFSKAFNIQYNDKNSQLQYVHQTSWGVTTRLIGAIIMVHGDDSGLKLPPRIAPLQVVIVPIAQHKEGVLDKAEELRQRIAKVARVKVDSSDKMPGWKFNEYEMKGVPVRLEVGPKDIENNQVVLVRRDTREKIFVSMDELETKIPELLDEIHNSMLEHARTHRDEHTYTAKTLDEFKEIADTKPGFIKAMWCGDTACEEKLKEVAGVSSRCMPFEQEEITDKCICCGKEAKHMVYWGKAY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H3_GRIJA
Sequence: MARTKQTARKSTGGKAPRKQLATKAARKSAPASGGVKKPHRFRPGTVALREIRRFQKSTELLVRKLPFQRLVREIAQDFKSDLRFQSSAVLALQEAAEAYMVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERT
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: DEFB_ANOCP
Sequence: VTCDLLSFEAKGFAANHSICAAHCLVIGRKGGACQNGVCVCRN
What is the function of this protein?
Antibacterial protein.  Strong activity against the Gram-positive bacteria M. luteus, B. megaterium and S. aureus.  Reduced activity against Gram-positive bacterium B. subtilis and weak activity against Gram-negative bacterium X. japonicus.  No detectable activity against the Gram-negative bacteria E. asbriae, E. coli, P. aeruginosa and S. marcescens.
What are the official names of this protein?
Defensin-B.
What is the protein family that this protein belongs to?
Belongs to the invertebrate defensin family. Type 1 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LGT_NITMU
Sequence: MLVHPQIDPIAIQLGPLAVRWYGLMYLLGFACFILLGRYRIKRNPEGAFTISMLDDMLFYGVLGVIVGGRLGHIFFYQFGYYLEHPLEIFAVWQGGMSFHGGFLGVIAAMALLARKYHLRWLVVTDFIAPLVPLGLGAGRIGNFINAELWGRPTDVPWGMIFPYVDNIPRHPSQLYEFALEGLAFFTLMWIYSARPRPVGAVSGMFLIGYGVFRSFAEFFREPDEGFMGMMTLGISMGQWLSLPMILAGVIMLVWAYRTQAPVSARGKAGKAGKAANAVVAGKRGSKER
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: OCT1_CAEEL
Sequence: MSFQAMETFAEISQEILMSATKPPDFDFVLEQVGNYGTYQIVFFFIICLPTSLPSAFSAFNIPFVVGNPPHTCHIPEGKEYLRPLTNDTQILSCKQYNETQINVFRAFTSAPVDTYSDRISLVPCQNGWDYDNSTYLDSLVTEFNLVCDQQAWIEISTTSFYVGSFIGNCLFGYVADKFGRRRSFFVILTVLIVCGTASSFAKDIESFIILRFFTGLAFPALFQIPFIICMEFMGNSGRIFSGLMTSLFFGAAMALLGVVAMFIRRWRQLTFFCNAPFAFYIIYYFFLPESPRWSVSVGKWADAKKQLKKIAKMNGKSNVDVDELVDSMKNHQNAAEEKETKRSHNVTDLFKTPNLRRKTLIVTYIWVMNAIIYNGLTLNVSNLPVDDYWSFIINGAVELPGYFVVWPLLQCAGRRWTLAATMIVCGIGCVSAMFMPDGYPWLVASASFIGKFGVGSGFAVIYIFAGELYPTVVRAIGMGMSSMVAGSGLLLAPHIVNLGKIVKILPLLIMGLMALSAGILTFFLPETLGAPLPMTIEDAENFGKKPEPDSGMFTQAAKKRESQPLLEPHTPMDRRRRSSRLMNI
What is the function of this protein?
Transports organic cations such as tetraethylammonium (TEA).  Displays a broad substrate specificity.
What are the official names of this protein?
Organic cation transporter 1, CeOCT1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: LACG_STRPG
Sequence: MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWYTAEPASDFYNRYPVDLKLSEEFGVNGIRISIAWSRIFPTGKGEVNPKGVEYYHNLFAECHKRHVEPFVTLHHFDTPEALHSDGDFLNRENIEHFVNYAEFCFKEFSEVNYWTTFNEIGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLFKDSGYSGEIGVVHALPTKYPFDANNPDDVRAAELEDIIHNKFILDATYLGKYSDKTMEGVNHILEVNGGELDLREEDFVALDAAKDLNDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRRKAPVDAPKTDWDWIIFPQGLYDQIMRVKADYPNYKKIYITENGLGYKDEFVDKTVYDDGRIDYVKKHLEVISDAISDGANVKGYFMWSLMDVFSWSNGYEKRYGLFYVDFETQERYPKKSAYWYKKVAETQVIE
What are the official names of this protein?
6-phospho-beta-galactosidase, Beta-D-phosphogalactoside galactohydrolase, PGALase, P-beta-Gal, PBG.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
Protein: GUAC_POLNA
Sequence: MEIFDYDNILLLPRKCRVESRAECDASVTLGQRSFRIPVVPANMKTVVNEDICVWMAQNGYFYVMHRFDLDNLQFVRDMQARGVYASISLGVKQPDYDTVDRLVAEGLAPEYITIDIAHGHADTVRKMIAYLKNHLPESFVIAGNVATPEAVIDLENWGADATKVGIGPGKVCITKMKTGFGTGGWQLSALKWCARVATKPIIADGGIREHGDIAKSIRFGATMVMIGSMLAGLEESPGQTVEVDGKLFKEYYGSASDFNKGEYKHVEGKRILEPIKGKLVDTLREMEEDVQSAISYAGGTRLMDIRKVNYVVLGGKNSNEDLMM
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
Protein: UVRB_THESQ
Sequence: MFKLVSEFEPTGDQPQAIEKLVEGLNRGMRFQTLLGVTGSGKTFTMANVIARVNRPALVISPNKTLAAQLYQEFKAFFPENRVEFFISYYDYYQPEAYIPTKDLYIEKNADINDVIVRMRMSTLKSVRTRRDVVVVASVSCIYATGDPNDFDRMNINLAVGDRIDVLELAERLARIGYQRTEDVSLSGCFRLKGDTVEIYPTYQDEGIRIEFFGDEVDSITLIDRFNRTTLEHLDKIIIYPAVEFITTEEKLKRAVESIREELNERLSELKKQGKILEYERLKQRTLNDIELLETMGYCPGIENYSRHFDGRKPGEPPYTLLDYFDKDFIVFIDESHITVPQLRAMYNGDRSRKKNLVEYGFRLPSAYDNRPLTFEEFLKKTGQIIFVSATPGDFELSISEQVVEQIIRPTGLVDPEVEVRPTAGQVDDLVNEIVKVKERGERALVTVLTKKTAELLSEHLTELGIRSLYLHSELDAIERVEVLKKLRRGDVDVVVGVNLLREGLDLPEVSLVAIMDADVEGFLRSETTLIQIIGRTARNINGKVIMYADRITNAMKRAIEETNRRRRIQLEYNKKHGITPRSVIKPLEIEVFEQFMVKEEPERYGDTVKNIFEMKKTLSPEEYMAVLEEEMYRAASELRYEDAAALRDELFRIREEIKKKKGL
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XERC_AGRFC
Sequence: MEYRVTEILTFAEPDLLNERQSWLATLAGERRLADNTVEAYERDTRQFLRFLTGYIGRPAAIRDIADLRPVDLRAFLANRRKEGAGARSLGRHLAGLRSLLHHLQKKGLVNAAGATAMRAPKQPKSLPKPLTDRQALKITTAEAQLNEEPWIAARNAAVLSLLYGCGLRISEALGLTPADFPPGTRSLRITGKGNKTRIVPLLAVVTEAVDTYRKLCPYALAADEPMFLGARGGKLQPAIIQREMQKLRGAFGLPENATPHALRHSFATHLLAGGGDLRTIQELLGHASLSTTQVYTGVDTARLLEIYDNAHPRA
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBCR_PORPU
Sequence: MTDLPFTLDQLRILKAIAKEGSFKKAANSLYVSQPAISLQIQNLERQLNVALFERGNKKATLTEAGSLLLRYGGRILALCEETCRALDDLQNLQGGTLIIGASQTTGTYLMPRLIGLFRQRYPQVAVQLQVHSTRLISWSVANGQVDLAIIGGEVPTELQDVLQVTSYAEDELALILPKSHPFSKLGDIQKEDLYRLRFIALDTQSTIRKVIDKVLSQHGIDSSRFKIEMELNSIEAIKNAVQSGLGAAFVSVSAIAKELELGIVHWAQIENVTIKRMLSIIVNPNRYKSKATETFSQEILTLFVTPSQHKTLGDKL
What is the function of this protein?
Trans-acting transcriptional regulator of RuBisCO genes (rbcL and rbcS) expression.
What are the official names of this protein?
Probable RuBisCO transcriptional regulator.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NU4C2_SYNY3
Sequence: MLEHFPWLTTMIALPLVAALFIPLIPDKDGKQVRWYALGVGLADFVLMSYVFWTNYDISSTGFQLQEKFSWIPQFGLSWSVSVDGISMPLVLLAGLVTTLSIFAAWQVDHKPRLFYFLMLVLYAAQIGVFVAQDMLLLFIMWELELVPVYLLVCIWGGQKRQYAAMKFLLYTAAASVFILVAALGLAFYGDVTTFDIAELGLKDYPIALELFLYAGLLIAFGVKLAIFPFHTWLPDAHGEASAPVSMILAGVLLKMGGYGLIRLNLGLLEDAHVYFAPILVILGVVNIIYGGFSSFAQDNMKRRLAYSSVSHMGFVLLGIASFTDLGISGAMLQMLSHGLIAAVLFFLAGVTYDRTHTLSLAQMGNIGKVMPTVFALFTMGAMASLALPGMSGFVSELAVFVGVSSSDIYSTPFKTVTVFLAAVGLVLTPIYLLSMLRQLFYGNNIPPSCNLEQDNLSANSDQEAVCFGTSCVLPGNAIYDDARPREVFIAACFLLPIIAVGLYPKLATQTYDATTVAVNSQVRQSYVQIAETNPRVYAEALTAPHIPTTDFATVKVQP
What is the function of this protein?
NDH-1 shuttles electrons from NAD(P)H, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase chain 4-2, NAD(P)H dehydrogenase I, subunit D-2, NDH-1, chain 4-2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi- pass membrane protein.
Protein: RIMP_NATTJ
Sequence: MTQHDNISQIENIIEPAVRDLGYDLVDVELIMENQKWVLRVYIDHGKGIGLDDCELVSNSLDQLLDEHDPIPHSYVLEVSSPGAERPLKKKKDFVNFAGKKVQIKTYVKLDGRKNFKGKLLGLEDEHVVLETFNSGEVKIPLDKIAKANLLLEL
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPI_CUCSA
Sequence: MNILLCSINTQKGLYDISGVEVGQHLYWQIGGFQVHAQVLITSWVVIAILLGSAIIAVRNPQTIPTDGQNFFEYVLEFIRDVSKTQIGEEYGPWVPFIGTMFLFIFVSNWSGALLPWKIIQLPHGELAAPTNDINTTVALALLTSVAYFYAGLSKKGLSYFGKYIQPTPILLPINILEDFTKPLSLSFRLFGNILADELVVVVLVSLVPLVVPIPVMFLGLFTSGIQALIFATLAAAYIGESMEGHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, chloroplastic, ATP synthase F0 sector subunit a, F-ATPase subunit IV.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: QUEF_PROM9
Sequence: MSTAKLDDSTQRPLYGERIIEESKIICFENPNKKRIYEISIQLPEFTCKCPFSGYPDFAKLNIIYQPNLSVYELKSLKLYINNFRDIKISHEEVVNRIMDDLVNEGSPHWIHLNAAFNPRGNVSMQLDIFSGQKRN
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_SPHAL
Sequence: MARPFFRRRKTCPFSAKDAPVIDYKDVRLLQGYLSERGKIVPSRITAVSTKKQRELAKAIKRARHIGLLPYIVK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: RAC2_BOVIN
Sequence: MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQPTRPQKRPCSIL
What is the function of this protein?
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state.  In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization.  Augments the production of reactive oxygen species (ROS) by NADPH oxidase (By similarity).
What are the official names of this protein?
Ras-related C3 botulinum toxin substrate 2, p21-Rac2.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Lipid-anchor. Note=Membrane-associated when activated.
Protein: MUTL_RHOPB
Sequence: MPVRQLPETVVNRIAAGEVVERPASVVKELVENAIDAGASRIDIFTDGGGRRRIGITDDGAGMTHADLTLAVDRHATSKLDDEDLLAIRTLGFRGEALPSIGSVAKLSITTRHAAEPHAWALAVEGGAKSPIVPAALSHGTRVEVSDLFYATPARLKFLKTDRTEAEAIREVVRRLAMARPDIAFSMAGEERAPVTWAAALPGAAGRLTRLGDILGGDFRSNAIEVRSERDGVVVEGFAAAPSLTRANALGQYLFVNGRPVRDKLIIGAVRAAYSDYLPRDRHPVVALFVSLDSREVDANVHPAKTEVRFRDAGLVRALIVHALKEGLAREGKRTAANDAGATISSFRPSFAPRANWDWRSSPSYPVAGSAAFDAAAGFAEREQSGFDVGAPSADVRSYQPSADFTDRPLGAARTQIHQTYIVAQTRDGLVVVDQHAAHERLVYEKLKASLATNGVQRQILLIPEIVELDEATVERLVARGEELATFGLVVESFGPGAVAVRETPSLLGKTDAGALLRDLAEHMAEWDEALPLERRLLHVAATMACHGSVRAGRVLKPEEMNALLREMEDTPNSGQCNHGRPTYVELKLSDIEKLFGRR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: MTLD_MYCPU
Sequence: MKKYKALHFGAGNIGRGLISDIYMKNNMDFALVDIDKDLIEKLNKQKSYSIIDFQTNKVFQISNFKAFSIDQEDEIKKWIEQADFISTSIGWSNLASLKKFFENVKLKEKAQIICFENGYKISSFFQSILNIDSNHFVNASVDKIIPNFKSDSLDVYVESYYEIILEQKNESQKKLNFVNYSTDLEAYINKKLFLVNAIHSTIGYLGYLKKYTYINEALNDQQILFKIKRLAKIINEILSKEYLLFKVDYLNDYLEKNLKRFSIKENQDLISRVARNPIQKLSKNERYFLIYNLVKKHNLEIDILLEIYKSIFYYDNKMDKESSKIQSTIENKSLAYALKKFSNLDQEDQEKILKSLAKK
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: RL16_SOLM1
Sequence: MLAPKKTKFRKMQKGRLRGPALRGASIDFGEIGIKALEHGKLTSQQIESARIAIMRHIKRGGKVWIRVFPDRVRTEKPAEVRQGKGKGSPVGWFAPVKPGRVLYEIKGVDIETAKEALTRAQHKLPIKTKIVVKEGL
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: Y2267_AERS4
Sequence: MVELKTIGLFLITAVAEIVGCYLPYLWLTQGRSVWLLLPAGLSLVLFAWLLSLHPTAAGRVYAAYGGVYIFVAILWLWLVDGIRPTLWDLVGSLVALFGMAIIMFAPRPA
What are the official names of this protein?
UPF0060 membrane protein ASA_2267.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HEM3_RAT
Sequence: MSGNGGAATTAEENGSMMRVIRVGTRKSQLARIQTDTVVAMLKTLYPGIQFEIIAMSTTGDKILDTALSKIGEKSLFTKELENALEKNEVDLVVHSLKDVPTILPPGFTIGAICKRENPCDAVVFHPKFIGKTLETLPEKSAVGTSSLRRVAQLQRKFPHLEFKSIRGNLNTRLRKLDEQLEFSAIILAVAGLQRMGWQNRVGQILHPEECMYAVGQGALAVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTVMKDGQLYLTGGVWSLDGSDSMQETMQATIQVPVQQEDGPEDDPQLVGITARNIPRGAQLAAENLGISLASLLLNKGAKNILDVARQLNDVR
What is the function of this protein?
As part of the heme biosynthetic pathway, catalyzes the sequential polymerization of four molecules of porphobilinogen to form hydroxymethylbilane, also known as preuroporphyrinogen.  Catalysis begins with the assembly of the dipyrromethane cofactor by the apoenzyme from two molecules of porphobilinogen or from preuroporphyrinogen.  The covalently linked cofactor acts as a primer, around which the tetrapyrrole product is assembled.  In the last step of catalysis, the product, preuroporphyrinogen, is released, leaving the cofactor bound to the holodeaminase intact.
What are the official names of this protein?
Porphobilinogen deaminase, PBG-D, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: YSXA_BACSU
Sequence: MVIHDLPLKLKDFPMKEKPRERLLKVGAENLANHELLAILLRTGTKHESVLDLSNRLLRSFDGLRLLKEASVEELSSIPGIGMVKAIQILAAVELGSRIHKLANEEHFVIRSPEDGANLVMEDMRFLTQEHFVCLYLNTKNQVIHKRTVFIGSLNSSIVHPREVFKEAFKRSAASFICVHNHPSGDPTPSREDIEVTRRLFECGNLIGIELLDHLVIGDKKFVSLKEKGYL
What are the official names of this protein?
UPF0758 protein YsxA.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: MAP_STAAR
Sequence: MKFKSLITTTLALGVLASTGANFNTNEASAAAKQIDKSSSSLHHGYSKIQIPYTITVNGTSQNILSSLTFNKNQQISYKDIENKVKSVLYFNRGISDIDLRLSKQAKYTVHFKNGTKRVVDLKAGIHTADLINTSDIKAISVNVDTKKQVKDKEAKANVQVPYTITVNGTSQNILSNLTFKKNQQISYKDLENNVKSVLKSNRGITDVDLRLSKQAKFTVNFKNGTKKVIDLKAGIYTANLINTGDIKNININVETKKQAKDKEAKANNQVPYSINLNGTTTNIQSNLAFSNKPWTNYKNLTAKVKSVLKSDRGVSERDLKHAKKAYYTVYFKNGGKRVIHLNSNIYTANLVHAKDIKKIEVTVKTGSKANAERYVPYTIAVNGTSTPNLSDLKFKGDSRVSYSDITKKVKSVLKYDRGIGERELKYAKKATYTVHFKNGTKKVINLNSKISQLNLLFVKDIKKIDVDVKTGSKAKADSYVPYTIAVNGTSTPIASKLKLSNKQLIGYQDLNKKVKSVLKHDRGINDIELKFAKQAKYTVHFKNGKTQVVDLKSDIFTRNLFSVKDIKKIDIDVKQHTKSNKALNKVSNIATKVKFPVTINGFSNVVSNEFAFLHPHKITTNDLNAKLRLALASDQGITKHDIGLSERTVYKVYFKDGSSKFVDLKAAKQDSKVFKATDIKKVDIEIKF
What is the function of this protein?
Both native and recombinant protein bound to labeled vitronectin, fibrinogen, recombinant osteopontin and fibronectin.  It was also shown to be able to bind to a 15-amino acid synthetic peptide of vitronectin.  Map could affect the severity of arthritis and osteomyelitis in mice through a T-cell-mediated mechanism and could play a role in abscess formation through a T-cell-independent mechanisms.  It could potentiate the survival of the bacterium by modulating host immunity (By similarity).
What are the official names of this protein?
Protein map, MHC class II analog protein.
Protein: AGO3_CHICK
Sequence: MEISSAGPVGAQPLLMVPRRPGYGTMGKPIKLLANCFQVEIPKIDVYLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLEPDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYDADPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVGPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRAGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA
What is the function of this protein?
Required for RNA-mediated gene silencing (RNAi).  Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them.  Possesses RNA slicer activity but only on select RNAs bearing 5'- and 3'-flanking sequences to the region of guide-target complementarity.
What are the official names of this protein?
Protein argonaute-3, Argonaute3, Argonaute RISC catalytic component 3, Eukaryotic translation initiation factor 2C 3, eIF-2C 3, eIF2C 3.
What is the protein family that this protein belongs to?
Belongs to the argonaute family. Ago subfamily.
What are the subcellular locations of this protein?
Cytoplasm, P-body.
Protein: ORN_LEGPL
Sequence: MKNNQNLIWIDLEMTGLEPEQDRIIEMATIVTDPQLNILAEGPVIAVSQPKILLDSMDAWNTKQHNQSGLVKRVLESNVSESQAEQLTIEFLKQYVDKGKSPMCGNSICQDRRFLYKYMPELAAYFHYRNLDVSSLKELVLRWRPELMNGVVKESKHLALDDIKDSINELIYYRQHFINLPEVKNDK
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.