PharMolix/UniProtQA huggingface dataset:
Protein: CTR3_MOUSE
Sequence: MLWQALRRFGQKLVRRRVLELGMGETRLARCLSTLDLVALGVGSTLGAGVYVLAGEVAKDKAGPSIVICFLVAALSSVLAGLCYAEFGARVPGSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNLIGNHISRTLKGTILLKMPHVLAEYPDFFALALVLLLTGLLVLGASKSALVTKVFTGMNLLVLSFVIISGFIKGELRNWKLTKEDYCLTMSESNGTCSLDSMGSGGFMPFGLEGILRGAATCFYAFVGFDCIATTGEEAQNPQRSIPMGIVISMFICFLAYFGVSSALTLMMPYYKLHPESPLPEAFSYVGWEPARYLVAIGSLCALSTSLLGSMFPMPRVMYSMAEDGLLFRVLAKVHSVTHIPIVATLVSGVIAAFMAFLFELTDLVDLMSIGTLLAHSLVSICVLILRYQPDQEMKSVEEEMELQEETLEAEKLTVQALFCPVNSIPTLLSGRVVYVCSSLLAVLLTVLCLVLTWWTTPLRSGDPVWVTVVVLILGLILAISGVIWRQPQNRTPLHFKVPAVPLLPLVSIFVNVYLMMQMTAGTWARFGIWMLIGFAIYFGYGIQHSMKEVKNHQTLPKTRAQTIDLDLTTSCVHSI
What is the function of this protein?
Uniporter that mediates the uptake of cationic L-amino acids such as L-arginine, L-lysine and L-ornithine (PubMed:9334265).  The transport is sodium ions- and pH-independent, moderately trans-stimulated and is mediated by passive diffusion (PubMed:9334265).
What are the official names of this protein?
Cationic amino acid transporter 3, CAT-3, CAT3, Cationic amino acid transporter y+, Solute carrier family 7 member 3.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: METK_HAEIE
Sequence: MSSYLFTSESVSEGHPDKIADQISDAVLDEILKQDPKARVACETYVKTGMALVGGEITTSAWVDIENLTRKVICDIGYEHSEMGFDGHSCAVLNAIGKQSADINQGVDRENPLDQGAGDQGIMFGYATNETDVLMPAAITYAHRLMEKQAEVRKSGKLAWLRPDAKSQVTLKYEDNKIVGVDAVVLSTQHSEEVSQKDLHEGVMEEIIKPVLPTEWLSKETKFFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGAARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQLSYAIGVADPTSIMVETFGTGKVANELLVSLVREFFDLRPYGLIKMLDLIQPIYRETAAYGHFGREQFPWEKVDHAEDLRIAAGLK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROB_NOSP7
Sequence: MTKTIVVKIGTSSLTQAETGQLALSTIATLAETLCHLRSQGHRVILVSSGAVGVGCARLGLTERPRAIALKQAVAAVGQGRLIRIYDDLFTTLQQAIAQVLLTRSDLVQRSRYLNAYNTFQELLGLGVIPIVNENDTVAIDELKFGDNDTLSALVASLIEADWLFLLTDVDRLYSADPRSVPDARPIALVSSIKELAELQIGSQGSQWGTGGMVTKISAARIAIAAGVRTVITQGRFPQNIEKIIQGELIGTHFEPQPEPTSARKRWIAYGLLPAGKLYLDEGAIAAISLAGKSLLAAGIKLVEGEFDTQDAVQLCDSNGNEIARGLVNYNSNDLQKIRGCHSREISTILGYAGAETVIHRDNLVLI
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GEA1_YEAST
Sequence: MHDVPMETVLAVNPATMIVKECINLCSAMNKQSRDKSQTSVAALLGGGSDIFLSQSDSFVDSFHNLPTSSYHDPLISGLVQLRLKINDLKGLDSLNALELLKPFLEIVSASSVSGYTTSLALDSLQKVFTLKIINKTFNDIQIAVRETVVALTHCRFEASKQISDDSVLLKVVTLLRDIITSSFGDYLSDTIIYDVLQTTLSLACNTQRSEVLRKTAEVTIAGITVKLFTKLKLLDPPTKTEKYINDESYTDNNLKDDIIGTTTSDNDLSSTDDDSAVADDNKNEKPVQQVIREQENDEETAEKAENVEPNYGITVIKDYLGLLLSLVMPENRMKHTTSAMKLSLQLINAAIEISGDKFPLYPRLFSLISDPIFKSVLFIIQSSTQYSLLQATLQLFTSLVVILGDYLPMQIELTLRRIFEILEDTTISGDVSKQKPPAIRELIIEQLSILWIHSPAFFLQLFVNFDCNLDRSDLSIDFIKELTKFSLPAAAVNTSNNIPPICLEGVLSLIENIYNDLQRFDRAEFVKNQKEIDILKQRDRKTEFILCVETFNEKAKKGIQMLIEKGFIDSDSNRDIASFLFLNNGRLNKKTIGLLLCDPKKTSLLKEFIDLFDFKGLRVDEAIRILLTKFRLPGESQQIERIVEAFSSKYSADQSNDKVELEDKKAGKNGSESMTEDDIIHVQPDADSVFVLSYSIIMLNTDSHNPQVKDHMTFDDYSNNLRGCYNGKDFPRWYLHKIYTSIKVKEIVMPEEHHGNERWFEDAWNNLISSTSVMTEMQRDFTNPISKLAQIDILQYEKAIFSNVRDIILKTLFKIFTVASSDQISLRILDAISKCTFINYYFSFDQSYNDTVLHLGEMTTLAQSSAKAVELDVDSIPLVEIFVEDTGSKISVSNQSIRLGQNFKAQLCTVLYFQIIKEISDPSIVSTRLWNQIVQLILKLFENLLMEPNLPFFTNFHSLLKLPELPLPDPDISIRKAKMSRSLLSTFASYLKGDEEPSEEDIDFSIKAFECVKASHPLSSVFENNQLVSPKMIETLLSSLVIEKTSENSPYFEQELLFLLEISIILISEASYGQEFGALIADHMINISNLDGLSKEAIARLASYKMFLVSRFDNPRDILSDLIEHDFLVKNEIFNTKYYESEWGKQVINDLFTHLNDVKYNERALKNVKFWNFLRILISAKDRQFAVYTFLEKYIQNGDIFVDDGNFMNILSLLDEMSCAGAVGTKWEQNYENSVEDGCEAPESNPYRSIIDLSSRSINITADLLSTVGRSNSALNKNEIIAAIQGLAHQCLNPCDELGMQALQALENILLSRASQLRTEKVAVDNLLETGLLPIFELDEIQDVKMKRITSILSVLSKIFLGQLVEGVTSNETFLRVLNVFNKYVDDPTVERQLQELIISKREIEKE
What is the function of this protein?
Activates the ARF proteins by exchanging bound GDP for free GTP.  Plays a role in maintaining mitochondrial morphology, and in the turnover of mitochondria through mitophagy (PubMed:25190516).
What are the official names of this protein?
ARF guanine-nucleotide exchange factor 1.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Membrane; Peripheral membrane protein. Endoplasmic reticulum. Mitochondrion. Note=Soluble and partially membrane- bound.
Protein: RL14_MYCBO
Sequence: MIQQESRLKVADNTGAKEILCIRVLGGSSRRYAGIGDVIVATVKDAIPGGNVKRGDVVKAVVVRTVKERRRPDGSYIKFDENAAVIIKPDNDPRGTRIFGPVGRELREKRFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: HBA_ANSIN
Sequence: MVLSAADKTNVKGVFSKISGHAEEYGAETLERMFTAYPQTKTYFPHFDLQHGSAQIKAHGKKVVAALVEAVNHIDDIAGALSKLSDLHAQKLRVDPVNFKFLGHCFLVVVAIHHPSALTAEVHASLDKFLCAVGTVLTAKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-A, Alpha-A-globin, Hemoglobin alpha-A chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: GAP2_CAEEL
Sequence: MKVIDEKPEDEEEEKDSGSKCKTPSSCTKKRVREKEEDLPPICHGWLIVCEGNPTKMMNKEVKLPWHAGYCVFEPRQSTMSCYKQEYPFIAGRMLHRNRTVRMDGDRSAFARHWGLLPEHYPSPPITGPHTIARSYTRPPKDRLPTKERFFSISRIPSRLTKFSTVRGMSIEFFDAIHDETNSGGAQVGGESLDRRGWSGASTGNRTTLTASVHNNLMNGRMSSSSHNLSTRLSGSTQNLNQPTNAYGNLLSRPFRSNPLKRTKSVSKMEKSLAEANQHSLHRVDASNTPSRDSSLYAQPPARRHLSQPAREGSLRACRSHESLLSSAHSTHMIELNEDNRLHPVHPSIFEVPNCFRLASTYYSCRTPLERAKWMENLRKTMNPRRDQQRRTENSMLIWILEAKGLPAKRKYYCEMTLDKTLYAKTSSKARTDNVFWGENFEFMMLPKIDEVCVSLFRESDSKKKKDTLIGYVTIGIDQLSSRSPVERWYTVNTSHSDSGTSRIASALGGKSSSQESPSLRIKARWQSVHILPLRAYDNLLETLCYNYLPLCEQLEPVLNVRDKEDLATSLVRVMYKHNLAKEFLCDLIMKEVEKLDNDHLMFRGNTLATKAMESFMKLVADDYLDSTLSDFIKTVLQCEDSCEVDPQKLGNVSNSSLEKNRALLMRYVEVAWTKILNNVHQLPKNLRDVFSALRCRLEAQNREALADTLISSSIFLRFLCPAILSPSLFNLVSEYPSPTNARNLTLIAKTLQNLANFSKFGGKEPHMEFMNEFVDREWHRMKDFLLRISSESKSGPEKNADAIVDAGKELSLIATYLEEAWTPLLQEKNGNKHPLSNVKSVLSELAECKRRSDNGVFHSPMVQQPSSDYENSPQQHVVPRHENVPAYRSTPPTGQATVLGRSTNRPATHLLTSDDYVLSSAFQTPSLRPGGTRLSDETGTSSSRTSDKTTSSAEIRDDTDSDFELREDRGRGGRNRKRLPRTDASPSSSQQASSGYLSNNPSRSSYSNSSSSSPVERMAALSIANPVFGPGPSSGYAIPAEPKEIVYQKRASPPPYDPDVHNYHYQPMQVYAVPPDCQVSPRTQATGGVNAQNRLSLPRTNPRASRNSTLLRPSVVNVPDDWDRTSDYWRDRGENNYRSQLESQVESQAREIERLMRENIELKSKMMSSTKTVDSKRSDSGASEDSYDSLSSLDRPSRQSLVVVPN
What is the function of this protein?
GTPase-activating protein, which acts as a negative regulator for the member of the Ras family let-60.  Probably decreases the signaling activity of Ras by stimulating its intrinsic GTPase activity, thereby lowering the levels of GTP-bound, active Ras.  The different isoforms may play a distinct role in specific tissues.
What are the official names of this protein?
Ras GTPase-activating protein gap-2, GTPase-activating protein 2.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TILS_CLOPE
Sequence: MKKKVIDFIKENSMIKSGDKVLVALSGGPDSVCLLHILSELRELLHIEVYAAHVNHCLRGESALKDEAYVEELCKNLNIKCFVKRVDINKISEEQNISTEMAGREERYKFFEELKNEYSLDKIAIAHNANDQAETLIMRALRGTGIEGLVGIKPVRDGIFIRPILILRRKEIEEYCEINNLNPRIDETNLEEIYSRNKIRLKAIPFIEDNFNPDIVATLNRLAYSCSKDVEFIQEEVEKRFPKLCIKENHSILIKEEAFNEKEALLTRIIKKALFEVSSKHNNFELKHIQDIIALKDKGTGKQINITNGVIALNEYGDIRIKLVDSKKAKENKVLNLENIKDELDKNQKVVIEDDILGNYELIVEDLKKGEKFSKDRFIKSFDYDKISNIDIRFRQNGDKIIPLGMKSSKKLKDIFINNKIPKEERDFIPLVLFNNEIAWIVGSNVSETFKVTNKTKKVIKITFKGKEN
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LDH_MACCJ
Sequence: MEKFKGNKVVLVGNGAVGSSYAFAMLNQGACDEFVIIDLNEDKAKGDAMDLNHGVVYAPSPMQVKYGTYEDCHDASLIVICAGAAQKPGETRLDLVGKNMKIFKSIVDEIMKSGFDGIFLIATNPVDVLTYAVQKFSGLPENQVIGSGTILDTARFRHLLSQEFNVSPNSVHGYIIGEHGDSELAVWSGTNIAGNSLYDILNENPEKQKLIEEIFVNTRDAAYEIIKAKGATYYGVAMGLMRISKAILNNENVVLTVSAKLNGEYGHDDVYIGVPAIINRNGIREVLETPLNTEEKEKFAKSVETLKAIQTPFFS
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_RHOPD
Sequence: MTTNLFNIFDPSTTIFNLEMNWISTLLIILFMPNFLWILPNRMNWLLFKMFNMLNNEMLMLYKMKKTKSPAFLFISLFMFILLNNFFSLFPYIFSSSSHMVFSVTLAIPFWMFFIILSTCKNTKNMIAHLIPLNTPIYLAPLMTIIETMSIIIRPMSLSIRLTANLIAGHLLMTLLNFNSLMIIIIFIQMFMMIFELCVALIQSYVFSILSSLYSSE
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane (By similarity).
What are the official names of this protein?
ATP synthase subunit a, F-ATPase protein 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: KCNN2_MOUSE
Sequence: MPIVLVRPTNRTRRLDSTGAGMGPSSHQQQESPLPTITHCAGCTTAWSPCSFNSSDMETPLQFQRGFFPEQPPPPPRSSHLHCQQQQQSQDKPCAPFAPLPHPHHHPHLAHQQPGSGGSSPCLRCNSCASSGAPAAGAGAGDNLSLLLRTSSPGGAFRTRTSSPLSGSSCCCCCSSRRGSQLNVSELTPSSHASALRQQYAQQPASASQYHQCHSLQPATSPTGSLGSLGSGPPLSHHHHHPHPAHHQHHQPQARRESNPFTEIAMSSCRYNGGVMRPLSNLSSSRRNLQEMDSEAQPLQPPASVVGGGGGASSPSAAAAASSSAPEIVVSKPEHNNSNNLALYGTGGGGSTGGGGGGSGHGSSSGTKSSKKKNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGAYDKASLYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIHPIPGNYTFTWTARLAFSYAPSTTTADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLIGSIHALPGLISQTIRQQQRDFIETQMENYDKHVSYNAERSRSSSRRRRSSSTAPPTSSESS
What is the function of this protein?
Forms a voltage-independent potassium channel activated by intracellular calcium (PubMed:11557517, PubMed:13679367, PubMed:14657188).  Activation is followed by membrane hyperpolarization.  Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization.
What are the official names of this protein?
Small conductance calcium-activated potassium channel protein 2, SK2, SKCa 2, SKCa2, KCa2.2.
What is the protein family that this protein belongs to?
Belongs to the potassium channel KCNN family. KCa2.2/KCNN2 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y1144_SHELP
Sequence: MDSLQNHLLIAMPSLKDTFFERSVIYLCEHNEQGAMGLMINRPIGVDVNELLRQMELDDFHTIESINSKVLVGGPVGQEKGFVLHTPQPQWSNSQQISDDLMLTTSRDVLTSLGSKEAPEQFIVALGYAGWGRHQLEQELADNTWLSIPANIDLMFNTDHESRWQKATESLGFDIWQLSSQAGHA
What are the official names of this protein?
UPF0301 protein Shew_1144.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: SYC_PROMA
Sequence: MPLKLTNTLTRRTETFSSLKPGEVSIYCCGVTVYDLCHLGHARSYIVWDVLRRYFIAQGYKVKFVQNFTDIDDKILARASKENCTMNEVSERNIEEFHRDMDALGILRPDRMPRATRCLEEIKSMIEELEKKGAAYSAEGDVYFAVMKHANYGKLSKRDLSEQQLNADGRVTDKEEARKQNPFDFALWKAAKEGEQSFPSPWGAGRPGWHIECSAMVLQELGETIDIHLGGADLIFPHHENEIAQSEVANGKKLAKYWLHNGMVNVGGQKMSKSLGNFTTIRALLKEGISAMTLRLFILQAHYRKPLDFTKESLDAASTGWKRLNVILCLGLMKHQTLNWPKPNIQESKITSLSKHSLNETLNLSRQQFIDALNNDINTSVAISILFELARPLRSLSNQIENGSSELISESDKHTSYSRWLLLTELANVLGLQAELPKTRTSKQSQNLDEVLIREAIQERKDAKLSGDFAKADKIREELNLKGVQLIDKKDGVTEWIQS
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPLA_MYCGE
Sequence: MQTFIITSPVFNPYFNAALEEWLLTEFRKNELVKVIYFWQNANTIVVGRNQNTYAEVNLKELESDKVNLFRRFSGGGAVFHDLGNICFSIILPRTGKVMENAYEQTTRNVVKFLNSLNVPAVFHGRNDLEINNKKFSGLAEYIAKDRLLVHGTLLFDTDFSKLAKYLNVDKTKIASKGVDSVAKRVVNVKEYLPNWTTAKFLEEMINFFTVTEKAETIVLTKDALAKVEKRAKEHFQSWEWNFGKTYEYNFKNKRYFNNAGLFECNVQVEKGTVVDIKFYGDFLSVVDITPVTKKLIGQKYDYKTFEKLFNELDHFSDYFGSLKPEQLLGVIFDNK
What is the function of this protein?
Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.
What are the official names of this protein?
Probable lipoate-protein ligase A, Lipoate--protein ligase.
What is the protein family that this protein belongs to?
Belongs to the LplA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMTL1_MOUSE
Sequence: MEQTEGNSSEDGTTVSPTAGNLETPGSQGIAEEVAEGTVGTSDKEGPSDWAEHLCKAASKSGESGGSPGEASILDELKTDLQGEARGKDEAQGDLAEEKVGKEDTTAASQEDTGKKEETKPEPNEVREKEEAMLASEKQKVDEKETNLESKEKSDVNDKAKPEPKEDAGAEVTVNEAETESQEEADVKDQAKPELPEVDGKETGSDTKELVEPESPTEEQEQGKENESEERAAVIPSSPEEWPESPTDEGPSLSPDGLAPESTGETSPSASESSPSEVPGSPTEPQPSEKKKDRAPERRVSAPSRPRGPRAQNRKAIMDKFGGAASGPTALFRNTKAAGAAIGGVKNMLLEWCRAMTRNYEHVDIQNFSSSWSSGMAFCALIHKFFPEAFDYAELDPAKRRHNFTLAFSTAEKLADCAQLLEVDDMVRLAVPDSKCVYTYIQELYRSLVQKGLVKTKKK
What is the function of this protein?
Plays a role in the regulation of contractile properties of both striated and smooth muscles.  When unphosphorylated, may inhibit myosin dephosphorylation.  Phosphorylation at Ser-301 reduces this inhibitory activity.
What are the official names of this protein?
Smoothelin-like protein 1, Calponin homology-associated smooth muscle protein, CHASM.
What is the protein family that this protein belongs to?
Belongs to the smoothelin family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere, I band. Cytoplasm, myofibril, sarcomere, M line. Nucleus. Note=Colocalizes with MYH2. In its unphosphorylated state, localizes to the cytoplasm. Phosphorylation at Ser-301 promotes translocation to the nucleus.
Protein: RL2_CLOBA
Sequence: MAVKKFNPITPSRRQMTMPTFEEITSQQPEKSLLVSLKSKAGRNAQGKITVRHRGGGVKRKYRIIDFKRNKDSIPAKVATIEYDPNRSAYIALVVYTDGEKRYIIAPAGLKVGDVIVSGPDSDIKPGNALPLKNIPVGTVIHNIELQKGKGGQLVRSAGNSAQLMAKEGNYATLRLPSGEMRYVRIECRATIGTVSNPTNDIVNIGKAGRKRHMGWRPTVRGSVMNPNDHPHGGGEGKSPVGRPSPVTPWGKPALGYKTRKNKKYSDRFIIKGRNAK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RS27A_ARCFU
Sequence: MAKGAESIYRYYEIKGEKVVRKKKFCPRCGEGVFLAEHKDRLSCGKCGYTEFKKK
What are the official names of this protein?
30S ribosomal protein S27ae.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS31 family.
Protein: GATA_MYCBT
Sequence: MTDIIRSDAATLAAKIAIKEVSSTEITRACLDQIEATDETYHAFLHVAADEALAAAAAVDKQVAAGEPLPSALAGVPLALKDVFTTSDMPTTCGSKILEGWRSPYDATLTARLRAAGIPILGKTNMDEFAMGSSTENSAYGPTRNPWNLDRVPGGSGGGSAAALAAFQAPLAIGSDTGGSIRQPAALTATVGVKPTYGTVSRYGLVACASSLDQGGPCARTVLDTALLHQVIAGHDPRDSTSVDAEVPDVVGAARAGAVGDLRGVRVGVVRQLHGGEGYQPGVLASFEAAVEQLTALGAEVSEVDCPHFDHALAAYYLILPSEVSSNLARFDAMRYGLRVGDDGTRSAEEVMAMTRAAGFGPEVKRRIMIGTYALSAGYYDAYYNQAQKVRTLIARDLDAAYRSVDVLVSPTTPTTAFRLGEKVDDPLAMYLFDLCTLPLNLAGHCGMSVPSGLSPDDGLPVGLQIMAPALADDRLYRVGAAYEAARGPLLSAI
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: GCNT3_SYNCA
Sequence: MKMTGWKKKLCRGHHLWALGCYMLLAVVALRLSLRLKCDVDSLDLESRDFQSQRCRDILYKNLKLPAKRSINCSGITRGDQEAVVQALLDNLEVKKKRLPFTDTYYLNITRDCERFKAQRKFIQFPLSKEELDFPIAYSMVVHEKIENFERLLRAVYAPQNIYCVHVDVKSPETFKEAVKAIISCFPNVFMASKLVPVVYASWSRVQADLNCMEDLLQSSVPWKYLLNTCGTDFPIKTNAEMVLALKMLNGKNSMESEIPSEYKKNRWKYRYEVTDRLYLTSKMKDPPPDNLPMFTGNAYFVASRAFVQHVLENPKSQRLIEWVKDTYSPDEHLWATLQRAPWMPGSVPYHPKYHISDMTAIARLVKWQDHEGDVSMGAPYAPCSGIHQRAICIYGAGDLYWILQNHHLLANKFDPRVDDNVLQCLEEYLRHKAIYGTEL
What is the function of this protein?
Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides.  Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis.  Has also I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development.
What are the official names of this protein?
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3, C2GnT-mucin type, C2GnT-M.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 14 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: BIOB_PROMM
Sequence: MTVLIAKDLTFEPVVHRYDWTVDEVRELLERPLMDLLWQAQLVHRTANPGYRVQLASLLSVKTGGCQEDCAYCPQSMHNSSDVEGQPDLVVQIQTVLERARAAKDAGADRFCMGWAWREIRDGAQFEAMLAMVSGVRELGLEACVTAGMLTEKQASRLADAGLTAYNHNLDTSPEYYDQIITTRTYQERIETLQKVRSAGITLCCGGIIGMGESTVDRASLLCVLANINPHPESVPINGLVAVEGTPLQDLPAVDPLEMVRMVATARILMPRSRVRLSAGREQLGREAQILCLQAGADSIFYGDSLLTTSNPDVKTDRELLSQAGVHANWEESDE
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: KN14A_ARATH
Sequence: MADQRSKTNRWNWEVSGFEPRKSSSNASFAESTGHRTTGPLLRRNSISTPSLPPKQAIASKVNGLKEKVKLAKEDYLELRQEATDLQEYSNAKLDRVTRYLGVLAEKSRKLDQFVLETEARISPLINEKKRLFNDLLTAKGNIKVFCRARPLFEDEGPSVIEFPGDCTICVNTSDDTLSNPKKDFEFDRVYGPHVGQAALFSDVQPFVQSALDGSNVSILSYGQTNAGKTYTMEGSNHDRGLYARCFEELFDLANSDSTSTSRFSFSLSVFEIYNEQIRDLLSETQSNLPNINMDLHESVIELGQEKVDNPLEFLGVLKSAFLNRGNYKSKFNVTHLIVSIHIYYSNTITGENIYSKLSLVDLAGSEGLIMENDSGDHVTDLLHVMNSISALGDVLSSLTSGKDSIPYDNSILTRVLADSLGGSSKTLMIVNICPSVQTLSETISCLNYAARARNTVPSLGNRDTIKKWRDVASDARKELLEKERENQNLKQEVVGLKKALKDANDQCVLLYSEVQRAWKVSFTLQSDLKSENIMLVDKHRLEKEQNSQLRNQIAQFLQLDQEQKLQMQQQDSAIQNLQAKITDLESQVSEAVRSDTTRTGDALQSQDIFSPIPKAVEGTTDSSSVTKKLEEELKKRDALIERLHEENEKLFDRLTERSMAVSTQVLSPSLRASPNIQPANVNRGEGYSAEAVALPSTPNKNNGAITLVKSGTDLVKTTPAGEYLTAALNDFDPEEYEGLAAIADGANKLLMLVLAAVIKAGASREHEILAEIRDSVFSFIRKMEPRRVMDTMLVSRVRILYIRSLLARSPELQTIRVSPVECFLEKPNTGRSKSTSRGSSPGRSPVRYLDTQIHGFKVNIKAERRNKLASVVSRMRGLEQDAGRQQVTGVKLREMQDEAKSFAIGNKALAALFVHTPAGELQRQIRLWLAENFEFLSVTSDDVSGGNGGQLELLSTAIMDGWMAGLGAAVPPHTDALGQLLSEYAKRVYTSQMQHMKDIAGTLAAEEAEDAGQVSKLRSALESVDHKRRKILQQMKSDAALLNLEEGSSPIPNPSTAAEDSRLASLISLDGILKQVKEITRQASVHVLSKSKKKALLESLDELTERMPSLLDIDHPCAQREIATAHQLVETIPEQEDTNILEQSHDRRPSLESISSGETDVSQWNVLQFNTGSSAPFIIKCGGNNNSELVIKADARVQEPKGGEIVRVVPRPSVLVNMSLEEMKQMFVQLPEALSLLALARTADGTRARYSRLYKTLAMKVPSLKDLVSELE
What is the function of this protein?
Kinesin-like protein required for chloroplast movements and anchor to the plasma membrane.  Mediates chloroplast movement via chloroplast actin (cp-actin) filaments.  Required for the chloroplast avoidance response under high intensity blue light (PubMed:20418504, PubMed:27310016).  Mediates redundantly with CHUP1 the nuclear avoidance response under high intensity blue light (PubMed:27310016).  May act as a mitotic kinesin (PubMed:15247388).  Probably involved in division plane determination (PubMed:16461285).
What are the official names of this protein?
Kinesin-like protein KIN-14A, Geminivirus Rep-interacting motor protein, Geminivirus replication protein-interacting protein, Kinesin CDKA-1-associated protein 1, Kinesin-like protein KCA1, Kinesin-like protein for actin-based chloroplast movement 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-14 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome. Cell membrane. Cytoplasm, cytoskeleton, phragmoplast. Note=Localizes to the spindle apparatus and condensed chromosomes in mitotic cells. Localizes in the forming cell plate and the cortical division zone (CDZ) during cytokinesis.
Protein: TNFA_HUMAN
Sequence: MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQREEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL
What is the function of this protein?
The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.
What are the official names of this protein?
Tumor necrosis factor, Cachectin, TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a.
What is the protein family that this protein belongs to?
Belongs to the tumor necrosis factor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Tumor necrosis factor, membrane form]: Membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Tumor necrosis factor, soluble form]: Secreted. SUBCELLULAR LOCATION: [C-domain 1]: Secreted. SUBCELLULAR LOCATION: [C-domain 2]: Secreted.
Protein: ASI1A_EUTRU
Sequence: MANYIDVLSFLAIICATVLATLAQDCSPEGARCVHDSECCFNECIDSLCQP
What is the function of this protein?
Induces neurotoxic effect on honeybees, including slow movements, disorientation and paralysis.  Since it provokes similar symptoms than omega-atracotoxin, it is probable that it acts in the same way by inhibiting voltage-gated calcium channels.
What are the official names of this protein?
U-Asilidin(1)-Eru1a.
What is the protein family that this protein belongs to?
Belongs to the asilidin-1 family.
What are the subcellular locations of this protein?
Secreted.