PharMolix/UniProtQA huggingface dataset:
Protein: ATCA3_ARATH
Sequence: MKTIILFVTFLALSSSSLADETETEFHYKPGEIADPSKWSSIKAEWKICGTGKRQSPINLTPKIARIVHNSTEILQTYYKPVEAILKNRGFDMKVKWEDDAGKIVINDTDYKLVQSHWHAPSEHFLDGQRLAMELHMVHKSVEGHLAVIGVLFREGEPNAFISRIMDKIHKIADVQDGEVSIGKIDPREFGWDLTKFYEYRGSLTTPPCTEDVMWTIINKVGTVSREQIDVLTDARRGGYEKNARPAQPLNGRLVYLNEQSSPSPTPRLRIPRVGPV
What is the function of this protein?
Reversible hydration of carbon dioxide.
What are the official names of this protein?
Alpha carbonic anhydrase 3, AtaCA3, AtalphaCA3, Alpha carbonate dehydratase 3.
What is the protein family that this protein belongs to?
Belongs to the alpha-class carbonic anhydrase family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma. Note=Targeted to the chloroplast via a protein-targeting pathway that uses the secretory system.
Protein: CCA_SHIBS
Sequence: MKIYLVGGAVRDALLGLPVKDRDWVVVGSTPQEMLDAGYQQVGRDFPVFLHPQTHEEYALARTERKSGSGYTGFTCYAAPDVTLEDDLKRRDLTINALAQDDNGEIIDPYNGLGDLQNRLLRHVSPAFGEDPLRVLRVARFAARYAHLGFRIADETLTLMREMTHAGELEHLTPERVWKETESALTTRNPQVFFQVLRDCGALRVLFPEIDALFGVPAPARWHPEIDTGIHTLMTLSMAAMLSPQVDVRFATLCHDLGKGLTPPELWPRHHGHGPAGVKLVEQLCQRLRVPNEIRDLARLVAEFHDLIHTFPMLNPKTIVKLFDSIDAWRKPQRVEQLALTSEADVRGRTGFESADYPQGRWLREAWEVAQSVPTKAVVEAGFKGVEIREELTRRRIAAVASWKEQRCPKPD
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: PANC_PHOV8
Sequence: MKLVQTIKELQSELDALRSEGKTIGLVPTMGALHAGHASLVKRAVAENDVVVVSDFVNPTQFNDKNDLAKYPRTLDADCELLEKVGAAFVFAPSVEEIYPEPDTRQFSYAPLDTVMEGRFRPGHFNGVCQIVSKLFMIVNPTRAYFGEKDFQQLAIIREMVKQIGFNGLEIVGCPIVREEDGLALSSRNARLSAVEREYALNISQTLFKSCTFAKSHPVAETQKFVEDAIAAAPGLRLEYFEIVDGTTLQKITDWEDTDYAVGCITVFCGEVRLIDNIKYKG
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_DESDA
Sequence: MDEILLQDPEIAKAIALESQRQMGKLELIASENIVSTAVREAQGSVLTNKYAEGYPGKRYYGGCEYVDMVETLAQERAKLLFDAQYVNVQPHSGSQANMAAYLAVLKPGDTILGMDLSHGGHLTHGSPVNFSGRLFKIISYGVQRETGRIDYDDVAAKAREHKPSVIVAGASAYPRAIDFARFRAIADEVGAKLVVDMAHIAGLVAAGLHQSPVPHAHITTTTTHKTLRGPRGGMILSTEDMGKTLNSQIFPGIQGGPLMHVIAAKAVALGEALHPAFKVYQQQVLDNAATLAACLTEAGYDLVSGGTDNHLMLVDLTSRDITGKDAEIALDTAGITVNKNTVPFETRSPFVTSGIRLGTAALTTRGMKQEHMRTVGQFIIAALEKRNDTAELEKIRKNVEEFAHQFPLFAHLA
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCKX1_HUMAN
Sequence: MGKLIRMGPQERWLLRTKRLHWSRLLFLLGMLIIGSTYQHLRRPRGLSSLWAAVSSHQPIKLASRDLSSEEMMMMSSSPSKPSSEMGGKMLVPQASVGSDEATLSMTVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKYTPTPRGEMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDITATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPRRVESNSSAHPWGLVGKSNPKTPQGTVLLHTPATSEGQVTISTMTGSSPAETKAFTAAWSLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAMLTTPSPSLTTALLPEELSPSPSVLPPSLPDLHPKGEYPPDLFSVEERRQGWVVLHVFGMMYVFVALAIVCDEYFVPALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCSLFSREILNLTWWPLFRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYVFTMKWNKHIEVWVKEQLSRRPVAKVMALEDLSKPGDGAIAVDELQDNKKLKLPSLLTRGSSSTSLHNSTIRSTIYQLMLHSLDPLREVRLAKEKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQEDVAEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLDWPETRQKQAIYLFLLPIVFPLWLTVPDVRRQESRKFFVFTFLGSIMWIAMFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWLLFSLINGLQPVPVSSNGLFCAIVLLFLMLLFVISSIASCKWRMNKILGFTMFLLYFVFLIISVMLEDRIISCPVSV
What is the function of this protein?
Calcium, potassium:sodium antiporter that transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+) (PubMed:26631410).  Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness (PubMed:20850105).  Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation (PubMed:20850105).
What are the official names of this protein?
Sodium/potassium/calcium exchanger 1, Na(+)/K(+)/Ca(2+)-exchange protein 1, Retinal rod Na-Ca+K exchanger, Solute carrier family 24 member 1.
What is the protein family that this protein belongs to?
Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: C_PHODV
Sequence: MSVKGWSASRPSEKILLTWKRFKRSATSGIKPTSQAKKAEPQVCKRKKSLRISMNHTRQQRDQTVSAMYSKKIREVERTILHLWRQKTVLKRIPKQDLQYDVIMFMITAVKRLRESKMLTVSWYQQALQVIGDSKEEREALMIALKILAKIIPKEMLHLTGDILLALTQTEQLM
What are the official names of this protein?
Protein C.
What is the protein family that this protein belongs to?
Belongs to the morbillivirus protein C family.
Protein: SYFA_DROME
Sequence: MHPDLTERILQHLETTDKADTLDLAALFAEDHQKIVGSLKSIQAHGELVTAETVTHKSLGLTDEGRAVVENGSHEALVYDLVPPEGIAQAALMAAGGANAKVGFSKAMSHGWILVDKSVTPPLVRRKVDTITDVVRNQLQQVALGKGDQLPAKEVADFKKRKLLQETTTKSFVLARGPEFATTLTKLETDLTVEMLANGLWDQLKFKAYNFDALGAPPTRGHLHPLLKVRTEFRQIFLEMGFSEMPTNNYVESSFWNFDALYQPQQHPARDAHDTFFVNHPAKSHKFPQDYLERVKKVHSVGGYGSKGYGYDWKLEEAQKNLLRTHTTAVSARMLYKLANQEGGFKAAKYFSIDKVFRNETLDATHLAEFHQVEGVIADVGLTLGDLIGTLYEFFRKLGITQLEFKPAYNPYTEPSMEIFCYHPGLAKWIEVGNSGVFRPEMLLPMGLPENVNVIAWGLSLERPTMIKYGINNIRDLVGPKVDLKMVEEGPICRLDHA
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBFA_CLOK5
Sequence: MTNYRSGRINEEMKREISNIIRNDMKDPRLSAMVSVTKVDVTKDQKYAKVFVSIYGEDKSKDDTFQVLKSSESFIRREVGHRVKLRNTPEIIIEMDNTIEYGMHINELLHKIKENEKHDNE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPEL_LISMF
Sequence: MLNEFIAIRRELHQIPETGYKELKTQAYLLDYISKLPSEHLEVKKWRTGILVLVKGTNPEKTIGYRTDIDALPITEETGLPFASKHPGNMHACGHDLHMSIALGVLTHFASKPAKDNLLFVFQPAEEGPGGAKPIMESAEFAEWRPDSIYGLHIAPEYKVGEIAIKPGLLFANTSELFISFKGKGGHAAYPHLANDMVVAASAFVGQMQTIISRNIDPMDSAVITIGRIHGGEIQNVIAETAYLDGTIRTLSPETMEIVWTRLKQLAKGWEEAYQCEVEFHPGSDYYQVDNDPVETEAFIHFLEEQYPESYVPARSAMTGEDFGYFLSEIKGFMFWLGVDSEYSLHHAKLSPKEEAIPFAIDVLIHFLESK
What is the function of this protein?
Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.
What are the official names of this protein?
N-acetyldiaminopimelate deacetylase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. N-acetyldiaminopimelate deacetylase subfamily.
Protein: DTX54_ARATH
Sequence: MEDKIQSDDFTSHKNPTLPQVIEELKELWAMVLPITAMNCLVYVRAVVSVLFLGRLGSLELAGGALSIGFTNITGYSVMVGLASGLEPVCSQAYGSKNWDLLTLSLHRMVVILLMASLPISLLWINLGPIMLFMGQNPEITATAAEYCLYALPDLLTNTLLQPLRVYLRSQRVTKPMMWCTLAAVAFHVPLNYWLVMVKHWGVPGVAIASVVTNLIMVVLLVGYVWVSGMLQKRVSGDGDGGSTTMVAVVAQSSSVMELVGGLGPLMRVAVPSCLGICLEWWWYEIVIVMGGYLENPKLAVAATGILIQTTSLMYTVPMALAGCVSARVGNELGAGRPYKARLAANVALACAFVVGALNVAWTVILKERWAGLFTGYEPLKVLVASVMPIVGLCELGNCPQTTGCGILRGTGRPAVGAHVNLGSFYFVGTPVAVGLAFWLKIGFSGLWFGLLSAQAACVVSILYAVLARTDWEGEAVKAMRLTSLEMRKVGQDEESSLLLLDDEKLGDVL
What is the function of this protein?
May function as a multidrug and toxin extrusion transporter in the export of IAA-conjugates from the cytoplasm into peroxisomes.
What are the official names of this protein?
Protein DETOXIFICATION 54, AtDTX54, Multidrug and toxic compound extrusion protein 54, MATE protein 54, Protein NOVEL ION CARRIER 2, Protein NIC2.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Peroxisome membrane; Multi- pass membrane protein.
Protein: RL7_NITMU
Sequence: MAIAKAEILDAIANMTVLELSQLIKEMEEKFGVSAAAAAVVAAAPAAGAAAAPAEEQTEFTVMLTAVGESKVNVIKVVRAVTGLGLKEAKDLVDGAPKPVKEGIAKADAEAIQKQLAEAGATAEIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: RL20_PSE14
Sequence: MARVKRGVIARKRHKKILKLAKGYYGARSRVFRVAKQAVIKAGQYAYRDRRQKKRQFRALWIARINAGARVNGLSYSRFIAGLKKASIEIDRKVLADLAVNEKAAFAAIVEKAKATLA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: PSAB_NICTO
Sequence: MALRFPRFSQGLAQDPTTRRIWFGIATAHDFESHDDITEERLYQNIFASHFGQLAIIFLWTSGNLFHVAWQGNFELWVQDPLHVRPIAHAIWDPHFGQPAVEAFTRGGALGPVNIAYSGVYQWWYTIGLRTNEDLYTGALFLLFLSAISLIAGWLHLQPKWKPSVSWFKNAESRLNHHLSGLFGVSSLAWTGHLVHVAIPASRGEYVRWNNFLDVLPHPQGLGPLFTGQWNLYAQNPDSSSHLFGTAQGAGTAILTLLGGFHPQTQSLWLTDIAHHHLAIAFIFLVAGHMYRTNFGIGHSMKDLLDAHIPPGGRLGRGHEGLYDTINNSLHFQLGLALASLGVITSLVAQHMYSLPAYAFIAQDFTTQAALYTHHQYIAGFIMTGAFAHGAIFFIRDYNPEQNEDNVLARMLEHKEAIISHLSWASLFLGFHTLGLYVHNDVMLAFGTPEKQILIEPIFAQWIQSAHGKTSYGFDVLLSSTSGPAFNAGRSIWLPGWLNAVNENSNSLFLTIGPGDFLVHHAIALGLHTTTLILVKGALDARGSKLMPDKKDFGYSFPCDGPGRGGTCDISAWDAFYLAVFWMLNTIGWVTFYWHWKHITLWQGNVSQFNESSTYLMGWLRDYLWLNSSQLINGYNPFGMNSLSVWAWMFLFGHLVWATGFMFLISWRGYWQELIETLAWAHERTPLANLIRWRDKPVALSIVQARLVGLVHFSVGYIFTYAAFLIASTSGKFG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2, PSI-B, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein.
Protein: LEPA_TREPA
Sequence: MRAMACVRRVRNFCIVAHIDHGKSTLADRLIERTRAVEERLQHAQMTDNMELERERGITIKSHAVCIPYTDAHGTEYVLNFVDTPGHADFAYEVSRAIAACEGALLVVDATQGVESQTISNLYLVLEHNLEIIPVINKIDLPTADVPRVLQQVEHDLGLDPASSVLISAKTGENVDALFDAIITRIPPPQGSGTAALQALVFDCHYDQYRGVVVHIRVFEGQVTSGMVIRFMSNGAEYRVEETGVFVFNLIAREALCAGDVGYLSANVKTVSDVQVGDTITDASCPCDTPRAGFRRVKPVVFSSVYPVDTDECEQLREALERLALNDASISWERDSSLALGHGFRCGFLGLLHLEVVQQRLEREFNQTVIFTAPQVQYYVFLKTGQRIVCDNPAHYPLEQEIAQVHEPYIRATIITPTEVLGAVMTLCIEKRAYQTAVNYLDQKRVELVYEMPLAEILFGFYDRLKSISHGYASFDYELIESKLTDLVKVDILINGKPVDALAQLCYRPHARRRAQAVCARLKEEISRQQFKIAIQGSIGGQIISRETVSPFRKDVLAKCYGGDITRKRKLLEKQKEGKKRMKMVGDVEIPQTAFLSVLKEASDA
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RPOZ_SHIDS
Sequence: MARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPEENDKTTVIALREIEEGLINNQILDVRERQEQQEQEAAELQAVTAIAEGRR
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: RLMN_SYNAS
Sequence: MHMNRINIRDMSLEEIESFISSLGKEKYRARQIMKWLYSQGAKSFDEMTTLSRAVRDQLNEMACITLPEIARVQQSSDGTRKILFRLQDNSFIESVLIPGKHNWTACISTQVGCHMGCRFCFTARQGFRRNLKPSEITGQLTMLQFYLPEGPEIKNIVMMGMGEPLANYRNTLKAIRIITSDYGLGFSTRKITLSTSGITPMIEQLGRDLCINLAISLNAPTDSIRSELMPVNRKYPLDRLLQACRNYPMPGRRMLTFEYILIDGVNSSPAHAEMLCRLLKGIRCKLNLIRFNEFPDCPFKTPSEETVLAFQQILVKHHYTAIIRASRGRDILAACGQLSGKALEEKL
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_ANADF
Sequence: MPSLRDIRNRIGSVKSTRQITKAMKMVSAAKLRRAQDAILKTRPYAQLLEQTLGRIAARAAADEVVAHPLLAPRAQRTAEVVVITSDRGLAGGFNANIARRTQRFLVENADRYERVQLATIGRKGRDYFRARRLEIRKDFTGVHANLAYEKAEAIAAEYTERYLSGEVDAVFLAYNEFKSAISQKPVVFQLLPIETPPDAGDGASIDFKYEPSREALLRDLLPRHVAMQVWRALLESAASEHGARMSAMESATKNAEEMIASLTLQYNRARQAYVTKELMEIVSGAEALK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: THIC_AGRFC
Sequence: MNIVAKTIPLVVTTGPHAASTKIHKPGILHPHIRVPMREIAVHPTAGEPPVTVYDSSGPYTDPSHPVLIENGLPRLRHDWVVARGDVEAYEGRHVKPEDNGFATGERLTPEFSVRHQPLKATAGKAVTQLAYARAGIITPEMEFIAIRENLGREAAKEKPTRDGESFGAHIPDYVTAEFVRQEVASGRAIIPANINHPELEPMIIGRNFLVKINANIGNSAVTSSMAEEVEKMVWAIRWGADTVMDLSTGRNIHNIREWIIRNSPVPIGTVPLYQALEKVNGIAEDLNWEVFRDTLIEQAEQGVDYFTIHAGVRLHYIPLTVNRVTGIVSRGGSIMAKWCLHHHKESFLYEHFEEICDICRAYDVSFSLGDGLRPGSIADANDAAQFAELETLGELTQIAWARDCQVMIEGPGHVPMHKIKENMDKQLKTCGEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPDRNDVKVGVITYKIAAHAADLAKGHPAAQVRDDALSRARFEFRWEDQFNLSLDPDTARSFHDETLPKEAHKVAHFCSMCGPKFCSMRISHDIRAEAQKEGLEAMAARFKEGGELYMPLPTPASAE
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: CH10_ACIBY
Sequence: MSNIRPLHDRVVIRRVEEETKTAGGILLPGSAAEKPSQGEVIAVGNGQITDNGVRALDVKVGDKVLFGTYAGTTVKVNGEELLIMKESDILAVLEG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPF_ACICA
Sequence: MRTRAKICGITRSQDVQAAVSAGADAIGLVFFPPSPRHVSIAQAQALLQHIPAYVQVVGLFVNATADQIKSVLDCVALDVLQLHGDETPEQCQEIALQCKRRWYKAIQVKPELDVVDEVQRYQAAGASAVLLDAWHPELKGGTGHQFDWSKFPKLDIPLILAGGLTPENVVDAIQTTHAFAVDVSGGVEAAKGIKDKQLIERFMQGVQCGSAK
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: RECF_LIMRJ
Sequence: MILTELHLHHFRNYQDLTVHFNPGVNVLIGHNAQGKTNMLEAIYVLSLTKSHRTSNDHELINWQEKSALISGTVEKSIGKIPLELQFSSKGKKAKVNHLEQARLSQYVGQLNAILFAPEDLSLVKGSPALRRHFMDREFSQMSSKYLYNAGQYRTLLRQKNKYLKQLKYRQQTDRVLLGVLSDQLAAFGAEVIIARQHFLKHLEGWAADLHQEISLNKESLRLEYVNQLKVSDDTTVEEAYQALFKLYQDNEQREIEQGTTIYGPHRDDIRFLVNDKNVQAFGSQGQQRTTALSVKLAEIDLMKEQTGEYPLLLLDDVLSELDTIRQTHLLTAIQNKVQTFLTTTSLSDVARQLINEPTIFEIEHGTLNKEEVK
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CALM_PHYPO
Sequence: MVDSLTEEQIAEFKEAFSLFDKDGDGNITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMADTDTEEEIREAFKVFDKDGNGFISAAELRHVMTNLGEKLSDEEVDEMIREADVDGDGQVNYDEFVKMMLSK
What is the function of this protein?
Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+).  Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
What are the official names of this protein?
Calmodulin, CaM.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
Protein: AROQ_HAES1
Sequence: MSRYAKILLLNGPNLNMLGKREPTHYGNLSLEDIEQRMQELAQQHQLELSCFQANSEEKLIDKIHQSFHLIDFIIINPAAYTHTSVALRDALLSVSIPFVEVHLSNIHRREPFRHHSYLSDIAEGVICGLGAQGYEFALQYASNYLKKIK
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: T184A_RAT
Sequence: MRNASGFLKTAGAPLVSATWLPPSPPPAMPMVAAGPQMERVDNGSQGAPQLFLTSALARGVSGVFVWTALLLTGHQIYSHLRSYTVPREQRFVIRLLFIVPIYAFDSWLSLLLLGGHPYYVYFDSVRDCYEAFVIYSFLTLCFQYLGGESAIMAEIRGKPIRSSCFYGTCCLRGMSYSITFLRFCKQATLQFCIVKPVMALITIILQAFDKYHDGDFNIHSGYLYVTLVYNASVSLALYALFLFYFATRDLLRPFEPVLKFLTIKAIIFLSFWQGMLLAILERCGVIPEVQAVDGTRVGAGTLAAGYQNFLICIEMLFASLALRYAFPSQVYSEKKNSPAPPAPMQSISSGLKETISPQDIVQDAIHNFSPAYQQYTQQSTHEAPGPGQGGHPSPSTHPGPASGSGGGKKSRNIEKRMLIPSEDL
What is the function of this protein?
Acts as a heparin receptor in vascular cells (PubMed:26769966).  May be involved in vesicle transport in exocrine cells and Sertoli cells (By similarity).
What are the official names of this protein?
Transmembrane protein 184A.
What is the protein family that this protein belongs to?
Belongs to the TMEM184 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasm, perinuclear region. Early endosome membrane; Multi-pass membrane protein. Endosome. Cytoplasmic vesicle, secretory vesicle membrane. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Colocalizes with CAV1 (PubMed:26769966).
Protein: RL19_XANC8
Sequence: MSKLNKTILADFEAAQIQRQLPEFNQGDTVVVNVKVKEGNRERVQAYEGVVIGTKNAGLNSAFTVRKISHGFGVERVFQTHSAIIDSVEVKRRGKVRAGKLYYLRGLEGKAARIKEDLAAAAQAKAARQAAAKAE
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: PRL_ANGJA
Sequence: MAQRFKGSNLFLTALLCLASQGHAVGLGDMLERASQLSDKLHSLSTSLTNDLDTHFPPMGKILMPRPSMCHTASLQTPHDKDQALRVPESELLSLARALLLSWNDPLLLLTSEAPTLSHPQNGVIYSKTRELQDQSNSLSSGLDRLIHKIGSSSKSLSPLPFQGGDLGSDKNSRLINFYFLLSCFRRDSHKIDNFLKLLRCRAAKQDRC
What are the official names of this protein?
Prolactin, PRL.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS14_AERS4
Sequence: MAKTSMKAREAKRAKLVAKFATKRTELKAIIVDMNASEEARWDAVLQLQQLPRDSSPSRQRNRCNITGRPHGFLRKFGLSRIKVREHAMKGEIPGLKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.