PharMolix/UniProtQA huggingface dataset:
Protein: YL576_MIMIV
Sequence: MDSSILSKLKYEPYSYSRCVKEYFITRDDNSDIKYFTSLIEIPTGNIGDNFLSFTDLNVFFYRLNSIDYYRSHKKFKICGAYITDLRSFKIKGVNDPTINFNSFSFPQFTEFNPLIRSRNDRLFVCVKFECELSELYTLNAFMINFEGNYCEIPKDMYNCLNFSNQLEYFEGYIEMNYSEPIEYEFIVRARSYYLDIFCEFCLYDINFYMMNNDSEIVESLNDVAVLEMEWENIDSRIDFKSFTEDNMLHLNTIEDVPMTNLPDVIPTDCFFSN
What are the official names of this protein?
Uncharacterized protein L576.
Protein: C560_PORPU
Sequence: MYNINRPISPHLTIYNTQKSSLFSIWHRISGVAMFTLIASPPLFLKLATFSYKSFNILDLMLNNSSLILPWFIVIISVIFLYHIINGIRHFLWDSVVNVNTESIIKDSNTLLALVFLIMLFKFIL
What is the function of this protein?
Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
What are the official names of this protein?
Succinate dehydrogenase cytochrome b560 subunit, Succinate dehydrogenase, subunit III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b560 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ATPG_MYCAP
Sequence: MSSIQSIQSRIKTVQSIRKITHAMELVSYSKLKKAKTAFDEVEKYNLLIDQTFNKIFENISHDDLKELMKSRNNSKSKLYIIVTSNLGLAGAYNANVIKLVKETVTSDDYLIIIGSYGVRALRQQYNEQIINLSDITTSKRTSTLVSKIIKRAFKYYRNGAVSSINFIYTKFINNLVQEELCEKVFPFDEQMIREHIDRKEIDYKLEFEPSAKDVLADAIPLFVDSKLHLAMATSLISEHSARRSAMENATRNSDSLITELDMEFKRKRQAKITNEIIEIVSGADAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MNTR_ECO57
Sequence: MSRRAGTPTAKKVTQLVNEEEHVEGFRQVREAHRRELIDDYVELISDLIREVGEARQVDMAARLGVSQPTVAKMLKRLATMGLIEMIPWRGVFLTAEGEKLAQESRERHQIVENFLLVLGVSPEIARRDAEGMEHHVSEETLDAFRLFTQKHGAK
What is the function of this protein?
In the presence of manganese, represses expression of mntH and mntS.  Up-regulates expression of mntP (By similarity).
What are the official names of this protein?
Transcriptional regulator MntR, Manganese transport regulator.
What is the protein family that this protein belongs to?
Belongs to the DtxR/MntR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBSD_ECO24
Sequence: MKKGTVLNSDISSMISRLGHTDTLVVCDAGLPIPKSTTRIDMALTQGVPSFMQVLGVVTNEMQVEAAIIAEEIKQHNPQLHETLLTHLEQLQKHQGNTIEIRYTTHEQFKQQTAESQAVIRSGECSPYANIILCAGVTF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPL_DEHMB
Sequence: MEADVIKLLAAGLAMGLGAIGPGIGVGILGFGALQAIGRNPEAKGSIFTNMILLVAFAESIAIFALVISIVLIFVA
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LIRA6_PANTR
Sequence: MTPALTALLCLGLSLGPRTHVQAGPLPKPTLWAEPGSVISWRSPVTIWCQGSLEAQEYRLYKEGSREPRDTQNPMEPKNKARFSIPSMTEHHAGRYRCYYRSPAGWSEPSDPLELVVTGFYSTPTLSALPSPVVASGGNVTLRCGSQKGYDHFVLMKEGEHQLPQTLDSQHLHSGGFQALFPVGPVTPSHRWTFTCYGSYRNTPQVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGESLTLQCGSDVGYDRFTLYKEGERDFLQLPGPQPQAGLSQANFTLGPVSRSHGGQYRCYGAHNLSSEWSAPSDPLNILIAGQFYDRVSLSLQPDPTVASGENVTLLCQSQGQFDTFLLTKEGAAHPPLRLRSKYQSQKYQAEFPMNPVTSAHAGTYRCYGSYSSNPHLLSFPSDPLKLMVSGPSGGPSLPPTGPPSTPASHAKDYTVENLIRMGMAGLVLVVLGILLFEAQHSQRSPQDAARR
What is the function of this protein?
May act as receptor for class I MHC antigens.
What are the official names of this protein?
Leukocyte immunoglobulin-like receptor subfamily A member 6, Leukocyte immunoglobulin-like receptor E.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: PUR7_GLOVI
Sequence: MILQPGAWAVADILYEGKAKIIYPTPDPAIVLAVFKDDATAFNAQKRGTISGKGAVNATVSAKLFLLLERSGVPTHYIDQPAANQLLFRRLKMIPLEVVVRNIVAGSLAKRTGLASGTVLGEAIVEFYYKNDALGDPLLNDEHILKVLTTVDALQLAELRRSALQVNAILSAFYRECGIRLVDFKLEYGYDGAGQLQLGDELSPDNCRLWTLEEDRILDKDRFRFDMGEVEGAYQEVLARVIAKAGP
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: PCDGE_PANTR
Sequence: MKASSGRCGLVRWLQVLLPFLLSLFPGALPVQIRYSIPEELAKNSVVGNLAKDLGLSVRDLPARKLRVSAEKEYFTVNPESGDLLVSDRIDREQICGKQPLCVLDFDTVAENPLNIFYIAVIVQDINDNTPLFKQTKINLKIGESTKPGTTFPLDPALDSDVGPNSLQRYHLNDNEYFDLAEKQTPDGRKYPELILQHSLDREEHSLHQLVLTAVDGGDPPQSGTTQIRVKVTDANDNPPVFSQDVYRVTLREDVPPGFFVLQVTATDRDEGVNAEITYSFHNVDEQVKHFFNLNEKTGEITTKDDLDFEIASSYTLSIEAKDPGDLAAHCSIQVEILDDNDCAPEVIVTSVFTPLPEDSPPGTVIALIKTRDRDSGENGEVYCQVLGNAKFILKSSSKNYYKLVTDGALDREEIPEYNLTITATDGGKPPLSSSIIVTLHISDVNDNAPVFQQTSYMVHVAENNPPGASIAQISASDPDLGPNGQVSYSIVASDLKPREILSYVSVSAQSGVVFAQRAFDHEQLRAFELTLQARDQGSPALSANVSLRVLVGDLNDNAPRVLYPALGSDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLIFADSLQEVLPDLSDRPEPSDPQAELQFYLVVALALISVLFFLAVILAISLRLRRSSRSDAWDCFQPGLSSKPGPGVLPSYSEGTLPYSYNLCVASQSAKTEFNFLNITPELIPAQDLLCDNASWEQNTNHGAAGVPFASDTILKQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.  May be involved in the establishment and maintenance of specific neuronal connections in the brain.
What are the official names of this protein?
Protocadherin gamma-B2, PCDH-gamma-B2.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: ASQB_EMENI
Sequence: MSSQSFRQIIGLAPSTATITDSTLIIVDAQNEYAQGLLRVQEVDQSRKVIADLLSRYRYMAHVCVSTTARTGAELGYDVLVVRDGVSDRAIPGVEANVLVDVALKEVTDAFGTVIASGEIKGVIYPVIFLYLYIQDLI
What is the function of this protein?
Isochorismatase-like protein; part of the gene cluster that mediates the biosynthesis of the aspoquinolone mycotoxins (PubMed:25251934).  Within the pathway, asqB converts [(1'E)-5'-(3',3'-dimethyloxiran-2'-yl)-3'-hydroxy-3'-methylpent-1'-en-1'-yl]-quinolinone B into yaequinolone C (By similarity).  The first step of the pathway is catalyzed by the nonribosomal pepdide synthetase asqK that condenses anthranilic acid and O-methyl-L-tyrosine to produce 4'-methoxycyclopeptin.  4'-methoxycyclopeptin is then converted to 4'-methoxydehydrocyclopeptin by the ketoglutarate-dependent dioxygenase asqJ.  AsqJ also converts its first product 4'-methoxydehydrocyclopeptin to 4'-methoxycyclopenin.  The following conversion of 4'-methoxycyclopenin into 4'-methoxyviridicatin is catalyzed by the cyclopenase asqI.  4'-methoxyviridicatin is the precursor of quinolone natural products, and is further converted to quinolinone B.  The prenyltransferase asqH1 then catalyzes the canonical Friedel-Crafts alkylation of quinolinone B with dimethylallyl cation to yield dimethylallyl quinolone, which is subjected to FAD-dependent dehydrogenation by the FAD-linked oxidoreductase asqF to yield conjugated aryl diene.  The delta(3') double bond then serves as the site of the second alkylation with DMAPP catalyzed by the prenyltransferase asqH2 to yield a carbenium ion intermediate, which can be attacked by H(2)O to yield a styrenyl quinolone containing a C3'-hydroxyprenyl chain.  The FAD-dependent monooxygenase asqG performs epoxidation of the terminal C7'-C8' olefin.  Finally, after dehydratation of the epoxide at C3 by asqC, the quinolone epoxide rearrangement protein asqO catalyzes an enzymatic 3-exo-tet cyclization to yield the cyclopropyl-THF ring system in aspoquinolone (Probable).
What are the official names of this protein?
Isochorismatase-like protein asqB, 4'-methoxyviridicatin/aspoquinolone biosynthesis cluster protein asqB, Aspoquinolone biosynthesis protein B.
What is the protein family that this protein belongs to?
Belongs to the isochorismatase family.
Protein: RPAC1_BOVIN
Sequence: MAAAQAVEEMRTRVVLGEFGVRNVHTTDFPGNYSGYDDAWDQDRFEKNFRVDVVHMDENSLEFDMVGIDAAIANAFRRILLAEVPTMAVEKVLVYNNTSIVQDEILAHRLGLIPIHADPRLFEYRNQGDEGGTEIDTLQFRLQVRCTRNPHAAKDSSDPNELYVNHRVYTRHMTWVPLGNQADLFPEGAIRPVHDDILIAQLRPGQEIDLLMHCVKGIGKDHAKFSPVATASYRLLPDITLLEPVEGEAAEELSRCFSPGVIEVQEIQGKKVARVANPRLDTFSREVFRNEKLKKVVRLARVRDHFIFSVESTGVLPPDVLVSEAIKVLMGKCQRFLDELDAVQMD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Common component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively.  RPAC1 is part of the Pol core element with the central large cleft and probably a clamp element that moves to open and close the cleft (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerases I and III subunit RPAC1, DNA-directed RNA polymerase I subunit C, RNA polymerases I and III subunit AC1.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RRF_RHOJR
Sequence: MIDEALFEAEEKMEKAVTVAKDDLGSIRTGRANPGMFNRIGIDYYGAFTPITQLASINVPEARLVVVKPYEASQLGAIETAIRNSDLGVNPSNDGNLIRISVPQLTEERRRELVKQAKSKGEDAKVSVRNVRRKAMDELSRIQKDGEAGEDEVGRAEKELDKTTARYVAQVDELVKHKEAELLEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDC1_CANGA
Sequence: MSEITLGRYLFERLNQVDVKTIFGLPGDFNLSLLDKIYEVEGMRWAGNANELNAAYAADGYARIKGMSCIITTFGVGELSALNGIAGSYAEHVGVLHVVGVPSISSQAKQLLLHHTLGNGDFTVFHRMSANISETTAMVTDIATAPAEIDRCIRTTYITQRPVYLGLPANLVDLKVPAKLLETPIDLSLKPNDPEAETEVVDTVLELIKAAKNPVILADACASRHDVKAETKKLIDATQFPSFVTPMGKGSIDEQHPRFGGVYVGTLSRPEVKEAVESADLILSVGALLSDFNTGSFSYSYKTKNIVEFHSDYIKIRNATFPGVQMKFALQKLLNAVPEAIKGYKPVPVPARVPENKSCDPATPLKQEWMWNQVSKFLQEGDVVITETGTSAFGINQTPFPNNAYGISQVLWGSIGFTTGACLGAAFAAEEIDPKKRVILFIGDGSLQLTVQEISTMIRWGLKPYLFVLNNDGYTIERLIHGEKAGYNDIQNWDHLALLPTFGAKDYENHRVATTGEWDKLTQDKEFNKNSKIRMIEVMLPVMDAPTSLIEQAKLTASINAKQE
What are the official names of this protein?
Pyruvate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
Protein: YACG_KLEP7
Sequence: MSEETIVNCPTCGKTVVWGEQSPFRPFCSKRCQLIDLGEWAAEEKRIPSAGDLSDSDDWSEQQP
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: MSP1_PLAFP
Sequence: MKIIFFLCSFLFFIINTQCVTHESYQELVKKLEALEDAVLTGYGLFHKEKMILNEEEITTKGASAQSGTSGTSGTSGTSGTSGTSGTSAQSGTSGTSAQSGTSGTSAQSGTSGTSGTSGTSPSSRSNTLPRSNTSSGASPPADASDSDAKSYADLKHRVRNYLFTIKELKYPELFDLTNHMLTLCDNIHGFKYLIDGYEEINELLYKLNFYFDLLRAKLNDVCANDYCQIPFNLKIRANELDVLKKLVFGYRKPLDNIKDNVGKMEDYIKKNKTTIANINELIEGSKKTIDQNKNADNEEGKKKLYQAQYDLSIYNKQLEEAHNLISVLEKRIDTLKKNENIKELLDKINEIKNPPPANSGNTPNTLLDKNKKIEEHEEKIKEIAKTIKFNIDSLFTDPLELEYYLREKNKKVDVTPKSQDPTKSVQIPKVPYPNGIVYPLPLTDIHNSLAADNDKNSYGDLMNPDTKEKINEKIITDNKERKIFINNIKKQIDLEEKKINHTKEQNKKLLEDYEKSKKDYEELLEKFYEMKFNNNFDKDVVDKIFSARYTYNVEKQRYNNKFSSSNNSVYNVQKLKKALSYLEDYSLRKGISEKDFNHYYTLKTGLEADIKKLTEEIKSSENKILEKNFKGLTHSANASLEVYDIVKLQVQKVLLIKKIEDLRKIELFLKNAQLKDSIHVPNIYKPQNKPEPYYLIVLKKEVDKLKEFIPKVKDMLKKEQAVLSSITQPLVAASETTEDGGHSTHTLSQSGETEVTEETEETEETVGHTTTVTITLPPKEVKVVENSIEHKSNDNSQALTKTVYLKKLDEFLTKSYICHKYILVSNSSMDQKLLEVYNLTPEEENELKSCDPLDLLFNIQNNIPAMYSLYDSMNNDLQHLFFELYQKEMIYYLHKLKEENHIKKLLEEQKQITGTSSTSSPGNTTVNTAQSATHSNSQNQQSNASSTNTQNGVAVSSGPAVVEESHDPLTVLSISNDLKGIVSLLNLGNKTKVPNPLTISTTEMEKFYENILKNNDTYFNDDIKQFVKSNSKVITGLTETQKNALNDEIKKLKDTLQLSFDLYNKYKLKLDRLFNKKKELGQDKMQIKKLTLLKEQLESKLNSLNNPHNVLQNFSVFFNKKKEAEIAETENTLENTKILLKHYKGLVKYYNGESSPLKTLSEVSIQTEDNYANLEKFRVLSKIDGKLNDNLHLGKKKLSFLSSGLHQLITELKEVIKNKNYTGNSPSENNKKVNEALKSYENFLPEAKVTTVVTPPQPDVTPSPLSVRVSGSSGSTKEETQIPTSGSLLTELQQVVQLQNYDEEDDSLVVLPIFGESEDNDEYLDQVVTGEAISVTMDNILSGFENEYDVIYLKPLAGVYRSLKKQIEKNIFTFNLNLNDILNSRLKKRKYFLDVLESDLMQFKHISSNEYIIEDSFKLLNSEQKNTLLKSYKYIKESVENDIKFAQEGISYYEKVLAKYKDDLESIKKVIKEEKEKFPSSPPTTPPSPAKTDEQKKESKFLPFLTNIETLYNNLVNKIDDYLINLKAKINDCNVEKDEAHVKITKLSDLKAIDDKIDLFKNHNDFDAIKKLINDDTKKDMLGKLLSTGLVQNFPNTIISKLIEGKFQDMLNISQHQCVKKQCPENSGCFRHLDEREECKCLLNYKQEGDKCVENPNPTCNENNGGCDADAKCTEEDSGSNGKKITCECTKPDSYPLFDGIFCSSSNFLGISFLLILMLILYSFI
What are the official names of this protein?
Merozoite surface protein 1, Gp195, Merozoite surface antigens, PMMSA.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: SYH_THET2
Sequence: MTARAVRGTKDLFGKELRMHQRIVATARKVLEAAGALELVTPIFEETQVFEKGVGAATDIVRKEMFTFQDRGGRSLTLRPEGTAAMVRAYLEHGMKVWPQPVRLWMAGPMFRAERPQKGRYRQFHQVNYEALGSENPILDAEAVVLLYECLKELGLRRLKVKLSSVGDPEDRARYNAYLREVLSPHREALSEDSKERLELNPMRILDSKSERDQALLKELGVRPMLDFLGEEARAHLKEVERHLERLSVPYELEPALVRGLDYYVRTAFEVHHEEIGAQSALGGGGRYDGLSELLGGPRVPGVGFAFGVERVALALEAEGFGLPEEKGPDLYLIPLTEEAVAEAFYLAEALRPRLRAEYALAPRKPAKGLEEALKRGAAFAGFLGEDELRAGEVTLKRLATGEQVRLSREEVPGYLLQALG
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_RUTMC
Sequence: MAHKKAGGSTNNGRDSVSKRLGVKRFGGQVVLSGNILVRQRGTKFHPGTNVRKGKDDTLFATMDGKVIFAKKGKFMHQYVSIETA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: YIHG_ECOLI
Sequence: MANLLNKFIMTRILAAITLLLSIVLTILVTIFCSVPIIIAGIVKLLLPVPVIWRKVSRFCDFMMYCWCEGLAVLLHLNPHLQWEVHGLEGLSKKNWYLLICNHRSWADIVVLCVLFRKHIPMNKYFLKQQLAWVPFLGLACWSLDMPFMKRYSRAYLLRHPERRGKDVETTRRSCEKFRLHPTTIVNFVEGSRFTQEKHQQTHSTFQNLLPPKAAGIAMALNVLGKQFDKLLNVTLCYPDNNRQPFFDMLSGKLTRIVVHVDLQPIADELHGDYINDKSFKRHFQQWLNSLWQEKDRLLTSLMSSQRQNK
What are the official names of this protein?
Probable acyltransferase YihG.
What is the protein family that this protein belongs to?
Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RUVC_PELTS
Sequence: MLIMGVDPGTAITGYGIVEYAGNRFALVECGCIRTMPGVPPAERLQALYGELVEIIKRHRPEHFAVEEIFFNKNTRTALTVGQARGVTVLAAAQSGLPVFEYTPLQVKQAVAGFGRAGKTQVQYMVKTILALPEVPAPDDVADALAVAICHAHHYTWERKLKLK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: DUT_PECAS
Sequence: MMKKIDVKIVDPRVGQQFPLPTYATPGSAGLDLRACLDQAIELKAGETTLIPTGLAIHIADTGLAAVILPRSGLGHKHGVVLGNLVGLIDSDYQGQLMVSVWNRGQQTFTVEPGERIAQMVFVPVVQAEFNLVEDFVGSERGEGGFGHSGRS
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: RECR_ACET2
Sequence: MSFYAAPIARLIEEFEKLPGIGHKTAQRLAFYVLDMPQEKVDRLANAITEAKQKTKFCSVCGNLTDTDVCPLCSSEKRDSSVICVVEDPRDVVAMEKIREFKGLYHVLHGAISPMQGIGPEDIKIKELLDRIKEGNVKEVIIATNPNIEGEATAMYISKLIKPLGVKTTRIAHGIPVGGDLEYADEVTLAKALEGRREI
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: MSHR_MANSP
Sequence: MPVQGSQRRLLGSLNSTPTATPHLGLAANQTGVRCLEVSVPDGLFLSLGLVSLVENVLVVTAIAKNRNLHSPMYCFICCLALSDLLVSGSNMLETAVTLLLEAGALAARAAVVQQLDNVIDVITCSSMLSSLCFLGAIAVDRYISIFYALRYHSIVTLPRARRAVAAIWVASVLFSTLFIAYYDHAAVLLCLVIFFLAMLVLMAVLYVHMLARACQHAQGIARLHKRQRLAHQGFGLKGAATLTILLGIFFLCWGPFFLHLTLIVLCPQHPTCSCIFKNFNLFLALIICNAIIDPLIYAFRSQELRRTLKEVLLCSW
What is the function of this protein?
Receptor for MSH (alpha, beta and gamma) and ACTH.  The activity of this receptor is mediated by G proteins which activate adenylate cyclase.  Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes.
What are the official names of this protein?
Melanocyte-stimulating hormone receptor, MSH-R, Melanocortin receptor 1, MC1-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RECU_BACCZ
Sequence: MTIRYPNGKRYNQASQPHKTPIKKHTYSNRGMSLEEELNETNEYYLTHNIACVHKKPTPLQIVKVDYPARSAAVVKEAYFKQPSTTDYNGVYKGKYIDFEAKETKNKTSFPLQNFHLHQIEHMKQVIAHNGIAFVIIKFTLFDELYLLDAKHIITFWNRQNTGGRKSITKEEIVEHGSLLSCGYHPRIDYIRVLDTVYFS
What is the function of this protein?
Endonuclease that resolves Holliday junction intermediates in genetic recombination.  Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands.  Promotes annealing of linear ssDNA with homologous dsDNA.  Required for DNA repair, homologous recombination and chromosome segregation.
What are the official names of this protein?
Holliday junction resolvase RecU, Recombination protein U homolog.
What is the protein family that this protein belongs to?
Belongs to the RecU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_CENSY
Sequence: MIPGLINARVTFHNSPVHALERFTFRDVGAALEGFRAGSGLDECVIVQTCNRVELFGASASPDMGSIRRTWASLAGIDESLFGGHLESSGGGEVLEHLLRLTSGLDSMVVGEEQILGQVKNAITSARTSGASGRRLNTLFDRAIRSGTRIRNSTGIGSGGVSVGSMAVRLVEENMDDLHSRSILLIGTGEVSTLVAKSLGKRGYDFSVASRTLQRSQAFCSAMGGSPVLFEDVLDGFGGYDVLFVATGAPYFLVTYDKISEVLESRGGMMILDLSNPRTVDEKVATLGGIKLMNLDQIAEMVSKNMRNRMSSVGKVEQMISGEVPVMEAAMNRLDAEPIAEAAFKEADALRRRELAKALQMLGNIGGNDAKVIDDLTRALVESIMSAPMNNLRRASEEGDADVVDAAARLFDYRRPG
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: ERIP6_RAT
Sequence: MEDDIWKAVDLSGVFDEDSVELRPRLTSVSSPSLSSTPPPSPLSSPSWSEEELPAPRSDGSPASSISAHKSYPKIFQTFKKDLSEVTVDRLMYPSFYERVQISIQTEDQSWLQRISARKRIKRIPSIEITEAPQENLASKLRENWVINPEEPKLSILCEMEFNEDFVNFFETSLRTLPSIGPPTILSYRKEYSCMDVILKDEQELGATCEFCGSDLQSLFFNMDTSLDDAGTKGKSHRSCCLQFQNLLDYITEERLTTKSPEMELISISPHAAHGSDADRLKAKEKAMQRKQERQMARHFTIIPEQSPVGTEEDTKHLKTISYQLSGDYLQNVRTEEVDLQITNISITCCDSWKICGKVMGNELLEKDYKHGSKFLTSFPDGTIQIFYPSGNLAIIRVPNKTDGFICIIQEDTATSPAILALFDSSGRSSCYHPNGNVWVYINILGGQYSDQAGNRIRTWNWSSTKPTPAFVSFKPVLLALNRYIGIRILEQDKVSIHFLAMGQQATICLGTKVVLQDPEEVPTLRFLSGDDLLLLASLIKIRRLFSKMEGCVNFPVSKAWERLKQPSYLSSLSLKLLALCQNSGIQQNIMETITELIKENE
What are the official names of this protein?
Glutamate-rich protein 6, Protein FAM194A.
What is the protein family that this protein belongs to?
Belongs to the ERICH6 family.
Protein: NTPPA_WOLPP
Sequence: MIEQSLDNLILASSSERRVALLKQINIKPGLVLPADIDESPLKKELPKDYSIRMAKSKAEKIQSANPNYFVLGVDTVVACGRRILLKAENVEQAEKCVRLLSGRRHRVYTSVCLLIPDQSKQHIRTVVTIVKFKRLSEQEIKYYLASEEWKNRAGGCNIQGLAGMFVLFLRGSYSSVIGLPLHETNCLLSNYFNLY
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_NATTJ
Sequence: MDSIFKDAEQKMKKALSSLKSELASLRAGRANPSILEGINVDYYGMATPLNQLANISAPEPRLLVVQPYDKSAIEDIEKAILKSDVGLTPNNDGQVIRLAVPQLTEERRNELVKIVRQKGEDTKVVVRNVRRDANDELKKLEKEKEISEDESIRGQDEIQKITDKYIKKIDEVMNAKEEEITSF
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINC_GEOKA
Sequence: MAKQKQQYVTIKGTKDGLTLHLDDRCSYDDLLKEIEERLVKQAGVAPDSPLVSVHLKIGNRYLTPAQEEEVRALIRRSKNLVVDSIESNVMSKAEAIEWMRKTEIVPVSRIVRSGQVLHVEGDLLLIGDVNPGGTVIAGGNIFILGALRGIAHAGYAGNKQAIIVASVMKPMQLRIGDIMSRAPDSKTDEGNEMECAYIDEHNQIVVDRLQLLMHLRPNLTRLERRM
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: MUTH_VIBC1
Sequence: MKPEPQSEAELMERAQDIAGLSFAELAEEAGMTVPENLKRDKGWVGQLLEWHLGAPAGSKPQQDFAKLGIELKSIPIGYSGKPLETTFVSVAPLTGVQGLTWETSHVRNKLSRVLWVPVEGEREIPLAERRVGSPLIWSPDQEEEQILKNDWEELMELIVLGKFDQISARHGEALHLRPKAANAKALTEAYSSNGKPIKTLPRGFYLRTQFTEQILLKHYINAQSE
What is the function of this protein?
Sequence-specific endonuclease that cleaves unmethylated GATC sequences.  It is involved in DNA mismatch repair.
What are the official names of this protein?
DNA mismatch repair protein MutH, Methyl-directed mismatch repair protein.
What is the protein family that this protein belongs to?
Belongs to the MutH family.
What are the subcellular locations of this protein?
Cytoplasm.