PharMolix/UniProtQA huggingface dataset:
Protein: RUVA_METPP
Sequence: MLGRLTGLLAEKSPPQVLIDVGGVGYEVDVPMSSFFNLPAIGEKVTLLTHFVVREDAQVLFGFLTAPERETFRMLIKISGVGPRTALSILSGLTVGDLAQAVTAQDASRLVKVPGIGKKTAERLLLELKGKLGADLGPAIGGKPASDAQADILQALIALGYSEREAQAAVKALPAEVGVSDGIKLALKALAR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: PRMA_FUSNN
Sequence: MKMKVLEAKIIYESDDLEKYKKIISDIFYSFGVTGLKIEEPILNKDPLNFYKDEKQFLISENSVSAYFPLNIYSEKRKKVLEETFAEKFSEDEDIVYNLDFYEYDEEDYQNSWKKYLFVEKVSEKFVVKPTWREYEKQDNELVIELDPGRAFGTGSHPTTSLLLKLMEEQDFSNKSVIDIGTGSGILMIAGKILGAGEVYGTDIDEFSMEVAKENLILNNISLNDVKLLKGNLLEVIENKKFDIVVCNILADILVKLLDEIKYILKENSIVLFSGIIEDKLNEVISKAEDVGLEVVEVKADKEWRAVYFKRK
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURC_CLOBJ
Sequence: MLFNFIKDKNKHIHFIGIGGISMSGLAEILLYHNFTISGSDMNSSPITKKLKDKGAHIYIGHKKENIKDADLIVYTAAIASDNPEIIEAKEKNIKLMDRADFLGDLMKGYKYNIAISGTHGKTTTTSMLSHVALKANVDPTILVGGNLDIINGNVRVGKSDFFITEACEYKSSFLKFFPYIGAILNIDADHLDYYRDLNDIKNAFSKFIKLIPKDGYLVAYGEDKNIQSIIKEANCNVITYGINSGDIQAHNIEYDEKACGNFDVVKDNQKLFSVKLNVPGKHNILNSLASICIGLASNMKCKDIIEGIESFFGTHRRFELKGCKNNITVIDDYAHHPTEISATLDAAKKYPHNKLFCVFQPHTYSRTLTLFDDFTKCFDNADEIILADIYAAREKDTGIISSDMLGDKLRDRGLKCTNFHKFDDIKNYLIENAKDGDLILTVGAGDIYKVGEMYINL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABL_BACSU
Sequence: MEQNKCALVTGSSRGVGKAAAIRLAENGYNIVINYARSKKAALETAEEIEKLGVKVLVVKANVGQPAKIKEMFQQIDETFGRLDVFVNNAASGVLRPVMELEETHWDWTMNINAKALLFCAQEAAKLMEKNGGGHIVSISSLGSIRYLENYTTVGVSKAALEALTRYLAVELSPKQIIVNAVSGGAIDTDALKHFPNREDLLEDARQNTPAGRMVEIKDMVDTVEFLVSSKADMIRGQTIIVDGGRSLLV
What is the function of this protein?
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).  It confers resistance to triclosan.
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabL, ENR, Enoyl-acyl carrier protein reductase III, NADPH-dependent enoyl-ACP reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: COAD_THEKO
Sequence: MRKKYRKVVVGGTFDRLHLGHKALLRKAFEVGKIVYIGLTSDEMVRNKPYAERILPYEHRLKDLLKFIEVNGYTNYRIIKIHTAIGFADSMKSLEAIVVSEETYKGALIVNRAREEKGLKPLDIVTIPIIKSYLGDKISSSLIRAGLIDPFGRPLHWKGNSPKDV
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SGPL1_MOUSE
Sequence: MPGTDLLKLKDFEPYLEILESYSTKAKNYVNGYCTKYEPWQLIAWSVLCTLLIVWVYELIFQPESLWSRFKKKLFKLIRKMPFIGRKIEQQVSKAKKDLVKNMPFLKVDKDYVKTLPAQGMGTAEVLERLKEYSSMDGSWQEGKASGAVYNGEPKLTELLVQAYGEFTWSNPLHPDIFPGLRKLEAEIVRMTCSLFNGGPDSCGCVTSGGTESILMACKAYRDLALEKGIKTPEIVAPESAHAAFDKAAHYFGMKIVRVALKKNMEVDVQAMKRAISRNTAMLVCSTPQFPHGVMDPVPEVAKLAVRYKIPLHVDACLGGFLIVFMEKAGYPLEKPFDFRVKGVTSISADTHKYGYAPKGSSVVMYSNEKYRTYQFFVGADWQGGVYASPSIAGSRPGGIIAACWAALMHFGENGYVEATKQIIKTARFLKSELENIKNIFIFGDPQLSVIALGSNDFDIYRLSNMMSAKGWNFNYLQFPRSIHFCITLVHTRKRVAIQFLKDIRESVTQIMKNPKAKTTGMGAIYGMAQATIDRKLVAEISSVFLDCLYTTDPVTQGNQMNGSPKPR
What is the function of this protein?
Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine (PubMed:9464245, PubMed:20097939).  Elevates stress-induced ceramide production and apoptosis (PubMed:9464245).  Required for global lipid homeostasis in liver and cholesterol homeostasis in fibroblasts (PubMed:20097939, PubMed:28262793).  Involved in the regulation of pro-inflammatory response and neutrophil trafficking (PubMed:21173151).  Modulates neuronal autophagy via phosphoethanolamine production which regulates accumulation of aggregate-prone proteins such as APP (PubMed:28521611).  Seems to play a role in establishing neuronal contact sites and axonal maintenance (By similarity).
What are the official names of this protein?
Sphingosine-1-phosphate lyase 1, S1PL, SP-lyase 1, SPL 1, mSPL, Sphingosine-1-phosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family. Sphingosine-1-phosphate lyase subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type III membrane protein; Cytoplasmic side.
Protein: SPEE_CLOTE
Sequence: MDLWLKEGQISDAVMTYKIKETLVRKKTEYQDLAIVDTYALGRMLVLDGIVQTSIKDEYVYHEMITHIPLYTHPNPKKVLVVGGGDGGTIREILKHPSVEKAVLCEIDEEVVKECKKHLPEISNNALEDSRCEVFIGDGIKYVNEHKNEFDVVIIDSTDPFGAAEGLFGGSFYGKISECLTEDGIFVAQTETPFYLPEIVKRVYDDSKAVFPVTKLFMAAIPTYPSGYWSFTIGSKKHDPEKAPVPEVLPFETKYYTPRLHSASFVLPKFVENLIFANISE
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGC_RHIET
Sequence: MAPKIFIDGEHGTTGLQIRTRMAGRRDVELLSIPEAERRNAAMREDMLNSADIAMLCLPDDASKEAVQMVSANNNVRVIDTSTAFRVNPGWAYGFAEMDKEQAEKIASARFVSNPGCYPTGAIGLIRPLRAAGILPDGYPVTVNAVSGYSGGGKQMIAQMENPDHPDAITAPHFLYGLPLTHKHVPEMTVHGLLDRAPIFSPSVGKFAQGMIVQVPLHLDDLAEGTTMESIHAALVAHYAGQEIVTVVPLSDSKALARVNAVELEGKDTMKLFVFGTPGGSQVNLVALLDNLGKAPRGVQNMDLMLAS
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSG_STRVG
Sequence: MSDPNLNASHDSVESVEDELDIVEAADAVDPDEAELADAEAGAPAEEAALHVESDEDEDEADVEVDAAVEEAADDAEVAEEEAEEAAPVEPAEPVDPIQALREELRLLPGEWYVIHTYAGYEKRVKANLEQRAVSLNVEEFIYQAEVPEEEIVQIKNGERKNVRQNKLPGYVLVRMDLTNESWGVVRNTPGVTGFVGNAYDPYPLTLDEIVKMLAPEAQEKAAKAAAEEAGLPAPAVKRTIEVLDFEVGDSVTVTDGPFATLQATINEINPDSKKVKGLVEIFGRETPVELSFDQIQKN
What is the function of this protein?
Participates in transcription elongation, termination and antitermination.
What are the official names of this protein?
Transcription termination/antitermination protein NusG, Butanolide receptor.
What is the protein family that this protein belongs to?
Belongs to the NusG family.
Protein: SYC_RHOOB
Sequence: MTLRLFDTETRALRDFAPLAPGHASVYLCGATVQGDPHIGHVRSGVAFDVLRRWLLAHDYDVAFVRNVTDIEDKILNKAAEAGRPWWEWAATFERSFTWAYQQLGVLPPSVEPRATGHITQMVEMMQRLIDNGHAYAAGGDVYFDVRSYPRYGSLSGHKLDDVHQGESAGECKRDPRDFTLWKAEKPGEPSWPTPWGRGRPGWHLECSAMAEFYLGAAFDIHCGGLDLVFPHHENEIAQAKCAGDDFAQYWLHNGWVTMGGEKMSKSLGNVLSVPNVLKKVRPQELRYYLGSAHYRSMLEYSDTALDEGAAAYRRIESFVMRTQERAGEVTIGRWTDAFARALDDDLAVPAALAEVHGKVREGNIALDGGDLEGARAIASQVRAMLGILGVDPLDEHWTQETADASAATDALDVLVRAELERRQTARAEKNWAVADEVRDRLIRAGIEVTDTPNGPEWSLKAGQ
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1209_STAAB
Sequence: MQIELTDAAVTWFKNELELPENNKVLVFFVRYGGEFQLKQGFSPAFTVEPKEDVDIGYEQQYDDLNVVVAEKDLWYFEDDHIIVNVVDHEDEISYSTK
What are the official names of this protein?
Uncharacterized protein SAB1209c.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: NU1C_SORBI
Sequence: MIIDRVEVETINSFSKSELLKEIYGLIWILPILALLLGITIEVLVIVWLEREISASIQQRIGPEYAGPLGLLQAIADGTKLLLKEDILPSRGEIPLFSIGPSIAVISVLLSFLVIPLGYRFVLADLSIGVFLWIAISSIAPIGLLMAGYSSNNKYSFSGGLRAAAQSISYEIPLTFCVLAISLLSNSSSTVDIVEAQSKYGFFGWNLWRQPIGFLVFLISSLAECERLPFDLPEAEEELVAGYQTEYSGIKYGLFYLVSYLNLLVSSLFVTVLYLGGWNFSIPYISFFGFFQMNKIIGILEMVIGIFITLTKAYLFLFISITIRWTLPRMRMDQLLNLGWKFLLPISLGNLLLTTSSQLVSL
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic, NAD(P)H dehydrogenase subunit 1, NDH subunit 1, NADH-plastoquinone oxidoreductase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: CYMC2_MELCT
Sequence: GLPTCGETCTLGKCNTPKCTCNWPICYKD
What is the function of this protein?
Probably participates in a plant defense mechanism (Potential).  Binds to and induces leakage in phospholipd membranes, particularly ones containing 1-palmitoyl-2-oleophosphatidylethanolamine (POPE) (PubMed:26322745).  In vitro, displays cytotoxicity against cultured cells but no hemolytic activity towards fresh erythrocytes (PubMed:26322745).
What are the official names of this protein?
Cyclotide mech-2.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Moebius subfamily.
Protein: RUSA_ECOL6
Sequence: MNTYSITLPWPPSNNRYYRHNRGRTHVSAEGQAYRDNVARIIKNAMLDIGLAMPVKIRIECHMPDRRRRDLDNLQKAAFDALTKAGFWLDDAQVVDYRVVKMPVTKGGRLELTITEMGNE
What is the function of this protein?
Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair.  Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of CC dinucleotides.  Corrects the defects in genetic recombination and DNA repair associated with inactivation of RuvAB or RuvC (By similarity).
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RusA, Holliday junction nuclease RusA, Holliday junction resolvase.
What is the protein family that this protein belongs to?
Belongs to the RusA family.
Protein: HBA_SEMEN
Sequence: VLSPADKTNVKAAWGKVGGHGGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPHALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR
What is the function of this protein?
Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1.  Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.
What are the official names of this protein?
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: LOVHK_BRUA2
Sequence: MAIDLRPFIPFGRGALSQATDPFRAAVEFTLMPMLITNPHLPDNPIVFANPAFLKLTGYEADEVMGRNCRFLQGHGTDPAHVRAIKSAIAAEKPIDIDIINYKKSGEAFWNRLHISPVHNANGRLQHFVSSQLDVTLELSRLVELEKERKTLSIETARSKDQLDYIVEVANIGFWTREFYSGKMTCSAECRRIYGFTPDEPVHFDTILDLVVLEDRMTVVQKAHQAVTGEPYSIEYRIVTRLGETRWLETRAKALTGENPLVLGIVQDVTERKKAEANKALVSREIAHRFKNSMAMVQSIANQTLRNTYDPEQANRLFSERLRALSQAHDMLLKENWAGATIQQICATALAPFNSTFANRIHMSGPHLLVSDRVTVALSLAFYELATNAVKYGALSNEKGVINITWAIMEDKGEKKFHMRWAESRGPEVMQPARRGFGQRLLHSVLAEELKAKCDVEFAASGLLIDVLAPITPEVFPGMGHNVPEQRIA
What is the function of this protein?
Photosensitive kinase that is involved in increased bacterial virulence upon exposure to light.  Once ejected from an infected animal host, sunlight acts as an environmental signal that increases the virulence of the bacterium, preparing it for infection of the next host (By similarity).  This photoreceptor protein is directly related to the bacterium's survival and replication within host macrophages, as it is required for optimal replication of bacteria inside macrophages.
What are the official names of this protein?
Blue-light-activated histidine kinase, BA-LOV-histidine kinase, BA-LOV-HK.
Protein: CQ050_HUMAN
Sequence: MDKHGVKTPLWKKETEELRAEDAEQEEGKEGSEDEDEDNQRPLEDSATEGEEPPRVAEEGEGRERRSVSYCPLRQESSTQQVALLRRADSGFWGWLGPLALLGGLTAPTDRKRSLPEEPCVLEIRRRPPRRGGCACCELLFCKKCRSLHSHPAYVAHCVLDHPDLGKAGAAGNS
What are the official names of this protein?
Uncharacterized protein C17orf50.
Protein: THYX_STRAW
Sequence: MTDTPADDLKPSFRSDVTVELVKHSAADSDVLWAARVSTAGEQSLDELKKDPERSKGLINYLMRDRHGSPFEHNSMTFFISAPIFVFREFMRHRVGWSYNEESGRYRELEPVFYVPGESRKLVQEGRPGKYVFVEGTQAQQELTGRVMEDSYRQAYEAYQEMLAAGVAREVARAVLPVGLFSSMYATCNARSLMHFLGLRTQHELAKVPSFPQREIEMVGEKMEAEWAKLMPLTYAAFNTNGRVAP
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
What are the official names of this protein?
Flavin-dependent thymidylate synthase, FDTS, FAD-dependent thymidylate synthase, Thymidylate synthase ThyX, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase ThyX family.
Protein: SYR_CAMLR
Sequence: MKTLVYKEIKEKLGRDFILENPKNKNLAHFATPLAFSLAKELKQNPMIIANDIVVKLKDCDCFESVEALNGYVNFKLSKAFLNSLATQALSDSENFAKDDKKEQSFLLEYVSANPTGPLHIGHARGAIFGDTLTRVARHLGYKFDTEYYVNDAGNQIYLLGLSILLAVKEHCLKEQVQYPDEYYKGEYIIDVAKEAFAEFEKDFFVEENIPQLALWAKDKMLKIIKQNLADAKIFIDAYVSETSYYSELENTLKALKEHGGTYEQDGKIWLASSVKGDEKDRVIIKDDGKGTYLAADIVYHKDKMSRGYDKCINIWGADHHGYIARMKAAMEFLGHDSQNLEIILAQMVSLLKNGEPYKMSKRAGNFILMGDVLEELGSDVLRYIFISKKCDTHLEFDVDEFKKEDSSNPVYYINYAHARIHQVFAKAGKSVDDVMYAKFESLNEDGMNLLFESLNLKAVLNDAFESRSLQKIPDYLKNLASLFHKFYNENKVVGSDNEDEFLKLFAICALSIKIAFALMGIEAKNKMNHD
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DSRB_YERPN
Sequence: MKVNDRVTVKTDGGPRREGVVLEVEEFSEGVMYLVSLADYPAGVWFFNEVDSQDGTFVEPLSQ
What are the official names of this protein?
Protein DsrB.
What is the protein family that this protein belongs to?
Belongs to the DsrB family.
Protein: GRPE_SULDN
Sequence: MSQEKKEELQSEAQVTKEETPQANEAAAEAEAIVNEFDLLQEELNSLKDKYARVHADFENIKKRLEREKYSAVEYANEKFAKDMIPVMDALHMALSSSSSIIDSAEHLEKLKEGIELTLKQLSTALEKHGITMVSHDAPFDPNIHNAIQSVDSDTVESGQIVQTFQTGYKYKDRPLREAMVVVAN
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCFH_ECO57
Sequence: MFLVDSHCHLDGLDYESLHKDVDDVLAKAAARDVKFCLAVATTLPGYLHMRDLVGERDNVVFSCGVHPLNQNDPYDVEDLRRLAAEEGVVALGETGLDYYYTPETKVRQQESFIHHIQIGRELNKPVIVHTRDARADTLAILREEKVTDCGGVLHCFTEDRETAGKLLDLGFYISFSGIVTFRNAEQLRDAARYVPLDRLLVETDSPYLAPVPHRGKENQPAMVRDVAEYMAVLKGVAVEELAQVTTDNFARLFHIDASRLQSIR
What are the official names of this protein?
Uncharacterized metal-dependent hydrolase YcfH.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.
Protein: PANB_ECO55
Sequence: MKPTTIASLQKCKQDKKRFATITAYDYSFAKLFADEGLNVMLVGDSLGMTVQGHDSTLPVTVEDIAYHTAAVRRGAPNCLLLADLPFMAYATPEQAFENAATVMRAGANMVKIEGGEWLVETVKMLTERAVPVCGHLGLTPQSVNIFGGYKVQGRGDEAGDQLLSDALALEAAGAQLLVLECVPVELAKRITEALAIPVIGIGAGNVTDGQILVMHDAFGITGGHIPKFAKNFLAETGDIRAAVRQYMAEVESGVYPGEEHSFH
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1460_CROS8
Sequence: MFCVIYRSARREQTYLYVEKKDDFSRVPEELLAGFGQPIMTMMLPLDGRKKLANADLEKVKQALKDQGYYLQLPPPPENLLKQHLESIGKK
What are the official names of this protein?
YcgL domain-containing protein ESA_01460.
Protein: MURE_STRT2
Sequence: MITIEQVLEVLKKDHNFRDIINQEHYHYSWTGVTFDHLSYDSRDITPSTLFFAKGAGFKLEFLESAVQAGLGFYVAEKDYQVGIPAILVSDIKQAMSLVAQAFYQHPQDKLKLLAFTGTKGKTTASYFAFNILKQSHKPAMLSTMNTTLDGKTFFKSNLTTPESLDLFRMMAEAVSNGMTHLIMEVSSQAYLTKRVYGLTFDVGVFLNISPDHIGPIEHPTFEDYFYHKRLLLKNSQAVIVNSGMNHFDFVAEEVADKDHDFYGKDSENTVKHSSGFSFKAKGKLAGDYDIQLIGDFNQDNAMAAGLACLRLGASLEDIKKGIAQTSVPGRMEILTQANGAKVFVDYAHNGDSLDKLLQVVTDHQKGKISLILGAPGNKGESRRQDFGHVLNTYPEINVILSTDDPNKEDPLTICQEIASHINRKVRIIIDREEAIKTAMSETTGSSDALVIAGKGADAFQIVNGKRTDYAGDIEVAKKYL
What is the function of this protein?
Catalyzes the addition of L-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase, L-lysine-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:L-Lys ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_BURCM
Sequence: MAIERTLSIIKPDAVAKNVIGQIYSRFEGAGLKIVASRMAHLSRGDAEKFYAVHAARPFFKDLVDFMISGPVMIQVLEGEGAILKNRDLMGATDPKKAEKGTIRADFADSIDANAVHGSDAAETAAVEIAFFFPEMNVYSR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y306_METJA
Sequence: MRQSKKDYKLKIFNLVKVMKLRVVCKDENLTDDELCIKCELCIGKDLMTIIEMMNEEYKIDEIIIPNCETLKRILNMD
What are the official names of this protein?
Uncharacterized protein MJ0306.
Protein: PNTB_RHORU
Sequence: MTHSLTMAAYIVAGVLFILALRGLSNPESARNGNRMGMVGMAIAILTTLLSPSVQAYAWIVLAIAIGGAIGTVIAKKVLMTALPQLVAAFHSLVGMAAVLVATGALLNPEAYGIGSAGAIHAGSLVEMSLGLAVGAITFSGSVIAFGKLQGLIAGKPVTFPMQHPLNAVLGILLVVLLVVFAATESHTAYFALMILAFALGFLLIIPIGGADMPVVISMLNSYSGWAAAGIGFTLGNPLLIIAGALVGSSGAILSYIMCKGMNRSIFNVILGGFGSEGGVAAAGGAAGDRSVKAGSAEDAAFIMKNASKVIIVPGYGMAVAQAQHALREMADVLKKEGVEVSYAIHPVAGRMPGHMNVLLAEANVPYDEVFELEEINSSFQTADVAFVIGANDVTNPAAKTDPSSPIYGMPILDVEKAGTVLFIKRSMASGYAGVENELFFRNNTMMLFGDAKKMTEQIVQAMN
What is the function of this protein?
The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.
What are the official names of this protein?
NAD(P) transhydrogenase subunit beta, Nicotinamide nucleotide transhydrogenase subunit beta, Proton-translocating transhydrogenase NADP(H)-binding component, Pyridine nucleotide transhydrogenase subunit beta, dIII.
What is the protein family that this protein belongs to?
Belongs to the PNT beta subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YDFA_ECOLI
Sequence: MDTIDLGNNESLVYGVFPNQDGTFTAMTYTKSKTFKTENGARRWLERNSGE
What are the official names of this protein?
Uncharacterized protein YdfA.
What is the protein family that this protein belongs to?
To E.coli YdaF.
Protein: RS12_STRA1
Sequence: MPTINQLVRKPRKSKVEKSDSPALNIGYNSHRKVHTKLSAPQKRGVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGALDTAGVADRKQGRSKYGAKRPKG
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: ZN730_HUMAN
Sequence: MGALTFRDVAIEFSLEEWQCLDTEQQNLYRNVMLDNYRNLVFLGIAVSKPDLITCLEQEKEPWNLKTHDMVAKPPVICSHIAQDLWPEQGIKDYFQEVILRQYKKCRHENLLLRKGCKNVDEFKMHKKGYNRHNQCLTTSHSKIFQCDKYVKVFHKFSNSNRHKIRHTSKKPFKCKECGKLFCILSHLAQHKKIHTGEKSYKCEEYGKAFNESSNCTTHKRITEKKPYKCKECGKAFNWFSHFTTHKRIHTGEKPYQCEKCGKFFNQSTNLTTHKRIHTGEKPYKCEECGKAFNQSSNLTEHKKIHTKEQPYKCEKCGKAFKWSSTLTKHKRIHNGEKPYKCEECGKAFNRSSTLNRHKITHTGGKPYKYKECGKAFNQSSTLTIHKIIHTVEKFYKCEECGKAFSRISHLTTHKRIHTGEKPYKCEECGRAFNQSSTLTTHKRIHTGEKPYECEECGKAFNRSSTLTTHKIIHSGEKIYKCKECGKAFRRFSHLTRHKTIHT
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Putative zinc finger protein 730.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CGR1_YARLI
Sequence: MSEQEEVQLPKLGKAPQVRVNGKNWKETKTPFRTSSLSVPLKHRSWERRQKERENLRMIKAKEKEMKDEKEAEHAEKVRRIKERRMAKEEKERLEKMTAILSAKKLARRKRKEKRNKLLRERN
What is the function of this protein?
Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit.
What are the official names of this protein?
rRNA-processing protein CGR1.
What is the protein family that this protein belongs to?
Belongs to the CGR1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.