PharMolix/UniProtQA huggingface dataset:
Protein: SAMC_XENTR
Sequence: MERREFCASLLAGGTAGMCVDLILFPLDTIKTRLQSPLGFSKSGGFRGIYAGVPSTAVGSFPNAAAFFVTYESAKQLLRSDSSYLSPIIHMAAASLGEVVACLIRVPSEVIKQRAQVSPSSTTYQMLSATLRQEGIKGLYRGYKSTVLREIPFSLVQFPLWESLKDLWSWKQGRAVDSWQSAVCGAFAGGFAAALTTPLDVAKTRIMLAKAGSGVASGNVLFALHEIWRTQGIMGLFAGVIPRMTAISLGGFIFLGAYDKVRTLMLREQ
What is the function of this protein?
Mitochondrial S-adenosyl-L-methionine/S-adenosyl-L-homocysteine antiporter.  Mediates the exchange of cytosolic S-adenosyl-L-methionine, the predominant methyl-group donor for macromolecule methylation processes, for mitochondrial S-adenosylhomocysteine(SAH), a by-product of methylation reactions.
What are the official names of this protein?
Mitochondrial S-adenosylmethionine carrier protein, SAM carrier, Solute carrier family 25 member 26.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: UBA3_YEAST
Sequence: MDCKILVLGAGGLGCEILKNLTMLSFVKQVHIVDIDTIELTNLNRQFLFCDKDIGKPKAQVAAQYVNTRFPQLEVVAHVQDLTTLPPSFYKDFQFIISGLDAIEPRRFINETLVKLTLESNYEICIPFIDGGTEGLKGHVKTIIPGITACWECSIDTLPSQQDTVPMCTIANNPRCIEHVVEYVSTIQYPDLNIESTADMEFLLEKCCERAAQFSISTEKLSTSFILGIIKSIIPSVSTTNAMVAATCCTQMVKIYNDLIDLENGNNFTLINCSEGCFMYSFKFERLPDCTVCSNSNSN
What is the function of this protein?
Catalytic subunit of the dimeric UBA3-ULA1 E1 enzyme.  E1 activates NEDD8/RUB1 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP.  E1 finally transfers NEDD8 to the catalytic cysteine of UBC12.
What are the official names of this protein?
NEDD8-activating enzyme E1 catalytic subunit, RUB1-activating enzyme E1, Ubiquitin-activating enzyme E1 3, Ubiquitin-like protein-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
Protein: RL33_METPP
Sequence: MAKGGREKIKLESTAGTGHFYTTDKNKKLHPEKMELMKFDPKARKHVAYKEVKLK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: LEXA_HYPNA
Sequence: MLTTKQKELLLFINDRIKDTGVSPSFDEMKEALDLASKSGIHRLITALEERGFIRRLANRARALEVLKLPDSAIPPPNARQRRDFRPALVTNQGAEAPRIAGMIPLVGRIAAGSPISAIQQENGQVASPGGLPEGDDYFALEVQGDSMIQAGILNGDTVILKRTNTAQTGDIVVALIDGEEATLKRLRRKGASVALEAANPAFETRIFGPDRVEVQGRLVALIRRYE
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: SYI_STRPN
Sequence: MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELNQGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIEQVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYEAAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGKGVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEKFGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGEDDYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISHSYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGDWVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEYGSSIWWERDAKDLLPEGFTHPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSSLITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTSVDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMTIRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQMQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEVQTFANQEEILDTWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIVSELTIAEGPAPEAALSFEDVAFTVERATGEVCDRCRRIDPTTAERSYQAVICDHCASIVEENFAEAVAEGFEEK
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MROH7_RAT
Sequence: MALSRGTSLILHEDPEKTPSPNSCEVPGIMSNTTPRPTPDLTLAPLPAHGVALAPALHPALSPDPEGVSGPVPNDISNPNASGAATPSSIQINTADTDDQSLDHTPKPNLAGTLCPDSQPVPSLSSTQATVLSPENSIKPLSEDIPKSFSSKVFGLGQSNSNPSRPEPNLYIRALSREALVRSHTISRQSSQTPLLLPSNTSLDRLHSGNISKVNLGRAQNSNEAITLTSHTIFASVSKEALSASWNTGSKGSVNVTSNSQPRSGLNVTVTHASHVSLIPGSSEGLSLHSSAQVPNSTLSPSSCMTLIMGSESLSMDSSFVVTDTSTLTLSSHRDYSEDNSIRTMPLEENLGKWDSLQGVTAFRSPPEGTSEDAKANESEKRDHDNDTALVENIISYQKNQDEVEVTGEKETTVKMMMRKIQEEPLDSLLSPARRQAMEILAQLSHTKPILSVRERVELVNTCVRSVFSLPSVQAMQEKDESKAEVIQTLYHQTLDSLQKLLNALFIEDPTPAGLKSILEPLGPWMNSGKVHERARAVNSNVSVLNYTLVTLPFFVSSGFPTLGLLLGRLLLRIGDPDEEIGREALDGITILYTILDLQKRTKNKEEINKKELYETNKRFLGPYNPASPCQNILRVIAEFGDFLGPQQVRDLLLAALEGLKDISETQGKDSIEMMQLASEVMLSSVLEWYRHRALEVIPEIMQGIYMQLSHIQEPRAREVALLPISFLASSFMTEVVVALLMCPLPLDSNGAEMWRQLILRKPSCDVRDLLDLLLTSLKEKPVTKKGRASIVPLAAASGLCELLSVNSCVGRVRRIYPQLLLALLIQVHYHIGLNLPSRVAPRKDSKDDIQPPLFVPVRWMVKVVKTLLLKMGCSYESAFLEEQGGWELMGQAESHYRAVSLLARAMVHYSCQELCRILYLLIPLLERGDERHKITATAFFVELFRMEQVRRIPEEYSLGRMVEGLSHRDPIMKVLSIRGLVILARRSEKMTKVQGLLPSMVKSLKNMDGVLVMEAVHDLKTIFKGQAKKLTDNSVYIEMLQTLLPHFIDARETVRTSCINTYGKVVKKLRMPRTQAMEEQLTSTLMPLLFIIQEGNAKVSQHFPLEFHTAGIFFLLVCRNV
What are the official names of this protein?
Maestro heat-like repeat-containing protein family member 7, HEAT repeat-containing protein 8.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: YOG2_SCHPO
Sequence: MEYHPSSQSPQVNPGMESQQGGYTYTYQQPAPPNSLHLQHPSILTRLPPLSSSVVSPSLASLPPFTPTSTYHSIAALTPPSYPQSSSAPSNNSYTIVPSPHDPSNAYSMHHVLQNTAPQSVPSPSPIEMVPPSPPKTGSNNSAPVTGKTVQSGNALNNSGLVKRQARKRTKTGCLTCRKRRIKCDERKPICYNCIKSKRQCEGYTHFPRPSGTFTASRRIPVSSLLSEPAPHGLAGQPTHPTFLYYIQSVAPSLCLWDACHFPPLSPYSSFSSIYWSSTVPELALRNPNISVALYAFASAKRHLTDDAVAFARQARVALTNITTTDSLLILVLLAVTQLYIPKSDIQLFNFAVDQVVKFDASLMTSPSDEIITYLLRRMFIRQVVLAGIVKPLASGLNPLPLLKCDLPPATTPTAVLDESLFHLGLRKLCHEKGLEPEFTKWSKNCPIDKADLPRLALLMIHAVFTSPVSLAQWVELILQNPDPTPAIHIARACLLAVHGVVDLGDLQMKVEKCVQSCEERQLQATISNFSTEVAQTNSSALAIGCQ
What are the official names of this protein?
Uncharacterized transcriptional regulatory protein C15D4.02.
Protein: DERL3_BOVIN
Sequence: MAWQGLATEFLQVPAVTRTYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLITNFLFFGPLGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFLGQALTAMLVYVWSRRSPGVRVNFFGLLTFQAPFLPWALMGLPMLLGNSILVDLLGIAVGHVYYFLEDVFPNQPGGKRLLLTPSFLKLLLDAPEEDPNYLPLPEEQPGPLQQ
What is the function of this protein?
Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins.  May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome.  May mediate the interaction between VCP and the misfolded glycoproteins.  May be involved in endoplasmic reticulum stress-induced pre-emptive quality control, a mechanism that selectively attenuates the translocation of newly synthesized proteins into the endoplasmic reticulum and reroutes them to the cytosol for proteasomal degradation.
What are the official names of this protein?
Derlin-3, Der1-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the derlin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: AQPZ_GLOVI
Sequence: MSLVKRSVAEFIGTFWLVLGGCGAAVLAAAFPNLGIGFAGVSLAFGLTLLTMAFAIGHISGCHINPAVSIGLWAAKRFPATELLPYIAAQVLGGIAGAGVLYLIAGGKAGFSLSGGFASNGYGLHSPGGYTLLACLVCEVVMTFMFLMIILGSTDRRAPKGFAPIAIGLSLTLIHLISIPVTNTSVNPARSTGPALFVGDWAIAELWLFWLAPIVGAALAGLFYHAFLDEPGEETEGTPASAQLRTEA
What is the function of this protein?
Channel that permits osmotically driven movement of water in both directions.  It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells.  It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
What are the official names of this protein?
Aquaporin Z.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FRDD_ALIFM
Sequence: MVNRNPKRSDEPVWWGLFGAGGTWFAMLTPVTILVLGILVPLGVIGPESMNYLRVAGFVTSIIGALFVIGSISMPMWHAMHRLHHGMHDLKFHTGTAGKIACYAAAALATVLSVVFIFMI
What is the function of this protein?
Anchors the catalytic components of the fumarate reductase complex to the cell membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit D, Quinol-fumarate reductase subunit D, QFR subunit D.
What is the protein family that this protein belongs to?
Belongs to the FrdD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MSMB3_PROFL
Sequence: MKVFFILIIFSFTLATCQGECYGSVPLPIDGEDVPLRTCVDTHDGQKHLIVSTWKTANSFSCECTQIGLQCCQKYVAVA
What is the function of this protein?
Shows an slight inhibitory effect toward the metalloproteinase brevilysin H6, but does not inhibit the metalloproteinases thermolysin, HR1A and HR1B.
What are the official names of this protein?
Small serum protein 3, SSP-3.
What is the protein family that this protein belongs to?
Belongs to the beta-microseminoprotein family.
What are the subcellular locations of this protein?
Secreted.
Protein: POTA_LEGPL
Sequence: MTTPLIEIRQIYKSYGNTPILNNVSLNVNHGEFLTLLGPSGCGKTTLLRLISGFEQPTLGEIFINGQCVNQLPPQKRDVHTVFQSYALFPHLSVFENVAFALRCKKTPNQEIRKRVFDALKLVQLESLAERNVKQLSGGQQQRVAIARAIINRPQVLLLDEPLSSLDYRLRKAMQSELKQLQKTLNMTFIFVTHDQEEALSMSDRIVVFNHGHIEQIGTPKAVYETPANLHVAMFIGEANIFDIQVHTVKDQDIVTNIEGIQLSCKNTGNYQVNEWLHLIVRPEDIRVWSLSEVEKTEGMLPGRIVDIIYKGSTVDLKVELSSGKIINASEFFDEDDDKLEYTLHETVWVQWLPGWEVLLPHEG
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PER_CAEEL
Sequence: MEPAGHSSATHNIVVPNANPTQPQPLAPAMREEGATLSPPNTWSSSSVEFLDDADDNRLLFTCTFTLPHGTVLSSATYADGFHEQYLTIGDNFLARLEPKGQSFILSAAAASVKQRIFARVTMPDGALRACELLCEFETDRAKITVLALRSAFSLQASHVSSNFHVFTFITKHSSTCALTHIDYASIPYLGLLPTDLIGKSLLAFVYSPDVHVVRQAHIDLHNSRGKIVKSIADLRLVAHNGSILRCQTEWSAYVNPWTRKMELVVARHRICSLPIGDSDVISSPPPGIQSNTLPPVMAKTFEDELRTIMNKPVPSTSRHSHHHHHSSLKDQNQGFPANIDLGAYIDKIVEQLVVNSTAQQQQKVAVAAAAAAQAAQAAVVATAQIRKVASAPPTTSTDPPLSYTQINCLENVHRLLKSQSRPESPAKQDEPFDEKKYPPQTPLTREALTLHTKRFEDEYKDTWCRRLKRLSDDVPSSPPAKRTTPIHWTSSSQNHYRTMAPAPPPPPGKNYQITYTPLDDLTDQKSTNTKSDVENVAYPISGSKFSTPMRLSIDGLLPRGATSTGGASPTSGTNSPPVFPKTSSSSSLLMLRDSQN
What is the function of this protein?
Specifically required for maintaining the timing of larval development and molting cycle rhythms.
What are the official names of this protein?
Period protein homolog lin-42, Abnormal cell lineage protein 42.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Expression is generally more enriched in the nuclei than the cytoplasm (PubMed:10550049). Cytoplasmic expression is enhanced in lateral seam cells during the molt periods of larval development (PubMed:16300753).
Protein: KUP2_MAGSA
Sequence: MSSHVPSFLRGTPDMTAHGGDGKSRNVAGLMLAAIGVVFGDIGTSPLYAMKETFSGPHAVAMDKGNILGVLSLVFWAITIIVSFKYVIIIMRADNRGEGGSLALLALVSHAAESNRRLSLMVSALGIFAAALFYGDSIITPAISVLSAVEGLQVAAPHLEQWVVPLTIVILFVLFAIQSHGTDLVGKMFGPVMLVWFLTLAILGIRNLSHAPSVLAALSPHYAISFLFREGWHAFLALGSVVLAVTGAEALYTDMGHFGRLPIRLAWYLLVLPALILNYFGQGALLIYNPEAIANPFFNLAPASLALPLVILATLATVIASQAVISGAFSVTRQAIQLGFLPRMEIIHTSEEEMGQIYLPFVNWLLMCMVMVLVVGFKTSSNLAAAYGVAVTGTMVIDALLVGTVMLLIWKWNPRKVKWLIGGFLVVDLAFFLANSIKIPDGGWFPLVVGGLLFTILTTWKDGRKRLLARLKADALPVEDFLASLSDRVPRVPGTAVFLTGTSEGVPIALLHNMKHNKIVHERVVLLTVIVEEVPFVPEERRLENRLLAPNFHRVFLRYGFMESPNIPKALAHARTDQLGFFYEPMSVSYFVSRETLLPTEKPGLRGLRDTLFATLARMATSAMDFFHLPSNRVVELGSQIEI
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup 2.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UVRC_STRPD
Sequence: MNELIKHKLELLPDSPGCYLHKDKEGTIIYVGKAKNLKKRVRSYFRGSHDTKTELLVSEIVDFEYIVTESDTEALLLEINLIQKNMPKYNIKLKDDKSYPFLKITNESFPRLVITRYIKKNDGLYFGPYPDSYTANEVKKLLDRIFPFKKCKNPINKVCFYYHLGQCCAHTICHTDKAYWDRLIDDVKHFLNGKDDKIIEDLRSKMLAASEEMAFERAAEYRDLISGIATMRTKQRVMSKDLQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNLFPYYNDAEEDFLTYMGQFYQDKQHFIPKEVFIPEAIDEELVAAIVPTKIIKPKRGEKKQLVALATKNARVSLQQKFDLLEKDIKKTSGAIENLGQLLRIDKPVRIEAFDNSNIQGTSPVAAMVVFVDGKPSKKDYRKFKIKTVVGPDDYASMREVLFRRYSRVKKEGLQAPNLIIVDGGVGQVNVAKDVIEKQLGLTIPVAGLQKNDKHQTHDLLFGNPLEVVPLPRRSEEFFLLHRIQDEVHRFAVTFHRQVRRKNSFSSTLDHISGLGPKRKQLLLRHFKTITAIASATSEEIQALGIPKTVVEAIQQQITDNKNDRSSP
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLU_GLAP5
Sequence: MSMTPREIVSELDAHIIGQNEAKRAVAIALRNRWRRMQLPEELRQEVTPKNILMIGPTGVGKTEIARRLAKLADAPFIKVEATKFTEVGYVGKEVDSIIRDLANVSMKLVRQQAVEKNRMRAQDAAEDRILDVLLPPAKDQWGNVQESDNTSTRQIFRKKLREGQLDDKEIEIDVAAQVSVEIMTPPGMEEMTSQLQSLFEGMSPNKTKKRKMKIKDALKVMVDEEAAKLVNPEELKQQAIEAVEQHGIVFIDEIDKICKKGEHSGGDVSREGVQRDLLPIIEGSTVNTKHGMVKTDHILFICSGAFQVARPSDLLPELQGRLPIRVELKSLNKEDFERILTEPNASLTLQYRELMKTEGVDIEFTKDGISRIAESAFRVNEKTENIGARRLHTVLERLMDSISFDASERSGEKIVIDEKYVSDALNDVVENEDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRF_MANSE
Sequence: MALKLLTLIALTCAAANAAKSSYKLCVPAAYMKDCEQMLEVPTKSKVALECVPARDRVECLSFVQQRQADFVPVDPEDMYVASKIPNQDFVVFQEYRTDEEPDAPFRYEAVIVVHKDLPINNLDQLKGLRSCHTGVNRNVGYKIPLTMLMKRAVFPKMNDHSISPKENELKALSTFFAKSCIVGKWSPDPKTNSAWKSQYSHLCSMCEHPERCDYPDNYSGYEGALRCLAHNNGEVAFTKVIFTRKFFGLPVGTTPASPSNENPEEFRYLCVDGSKAPITGKACSWAARPWQGLIGHNDVLAKLAPLREKVKQLADSGAADKPEWFTKVLGLSEKIHHVADNIPIKPIDYLNKANYTEVIERGHGAPELVVRLCVTSNVALSKCRAMSVFAFSRDIRPILDCVQENSEDACLKSVQDNGSDLASVDDMRVAAAAKKYNLHPVFHEVYGELKTPNYAVAVVKKGTAYNKIDDLRGKKSCHSSYSTFSGLHAPLFYLINKRAIQSDHCVKNLGEFFSGGSCLPGVDKPENNPSGDDVSKLKKQCGSDSSAWKCLEEDRGDVAFVSSADLSHFDANQYELLCLNRDAGGRDVLSSFATCNVAMAPSRTWVAAKDFLSDVSIAHTPLSLAQMLATRPDLFNIYGEFLKNNNVIFNNAAKGLATTEKLDFEKFKTIHDVISSCGLA
What is the function of this protein?
Transferrins are iron binding transport proteins which bind Fe(3+) ion in association with the binding of an anion, usually bicarbonate.  This transferrin binds only one Fe(3+) ion per protein molecule.
What are the official names of this protein?
Transferrin.
What is the protein family that this protein belongs to?
Belongs to the transferrin family.
What are the subcellular locations of this protein?
Secreted.
Protein: FUMC_PROMP
Sequence: MTKNFRFEKDSMGQIKVPSEALWGAQTQRSIINFSIGEELIPIELIYSLTVIKRAAAISNFKLGLINNVKKDLIIEACTEILDGKHDSQFPLKIWQTGSGTQTNMNINEVISNIAALKTNSGLGSHHPIHPNDDVNKSQSTNDTFPAAIQISVVTQIIKKLVPSIKELTKVLDSKSNKWKDLIKIGRTHFQDAVPISLGQEVSAWSKQLKDAEDALIISLNELCFLPLGGTAVGTGINCPKDFSKESIKSISEYTGLFFYKSKNHFSLMASHDRLAQVMGQIKILASALFKISNDIKILSSGPRSGIYELIIPKNEPGSSIMPGKVNPTQCEALSMVCTQVMGFEYAVSIANASGTLQMNEYKPLIGFNILTSIKLLNHAISNFRLKLVEGIQPNPKTIKANLENSLMLVTALVPKIGYEKAAEIANLAFNESINLKEATIKLGYLTANEFEDAINTNKMI
What is the function of this protein?
Involved in the TCA cycle.  Catalyzes the stereospecific interconversion of fumarate to L-malate.
What are the official names of this protein?
Fumarate hydratase class II, Fumarase C, Aerobic fumarase, Iron-independent fumarase.
What is the protein family that this protein belongs to?
Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHA2_SCHPO
Sequence: MSASKIAFLGPRGTFSHQAALLARPDSLLCSLPSFAAVLEALSSRQVDYAVLPIENSTNGAVIPAYDLLKGRDDIQAVGEVLVPAHHCIIGKSLENVQKILSHPQAFGQCSKWISANVPNAEFVSVSSTSQAAALASKDITGTIVAISSELCAVENQFNLLVKNIEDDSNNRTRFLLLRSGGFQDDLSPLKEKSLLQFYLSHPKKLSAVFEVFAAHKVVITNLVVRPSCKFPWTYIYFVECLGMEKHLIDRVGKYCDTFTFMGSYTNQISYF
What is the function of this protein?
Putative prephenate dehydratase required for the syntheis of L-phenylalanine.
What are the official names of this protein?
Putative prephenate dehydratase, PDT.
What is the protein family that this protein belongs to?
Belongs to the PHA2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: FUCT1_DROME
Sequence: MYKNLEEHNRLVNKYLKIFFVVSLYWCTSILTVFVNKHLLSSDTVNLGAPLFMSWFQCVVSTVICFVASRLSRKYPSVFTFPEGNPLDIDTFRKILPLSVLYTLMIGANNLSLSYVTVAFYYIGRSLTTVFSVVLTYVILRQRTSFKCLLCCGAIVVGFWLGVDQESLTEVFSWRGTIFGVLSSLALAMFSIQTKKSLGYVNQEVWLLSYYNNLYSTLLFLPLIIINGELESIITYPHLWASWFWAAMTLSGLCGFAIGFVTALEIKVTSALTHNISGTAKACAQTVIATQYYHDVRSALWWTSNVVVLVASAAYTRVKQLEMMRQHQQRSTATQKA
What is the function of this protein?
Involved in GDP-fucose import from the cytoplasm into the Golgi lumen.  Plays a major role in the fucosylation of N-glycans.  Functions redundantly with Efr in the O-fucosylation of Notch, positively regulating Notch signaling.
What are the official names of this protein?
GDP-fucose transporter 1, Neuronally altered carbohydrate, Solute carrier family 35 member C1 homolog.
What is the protein family that this protein belongs to?
Belongs to the TPT transporter family. SLC35C subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: GSH1_HAHCH
Sequence: MSEKLAARLEKLRRRHPQALADIYRGIEKEGLRVDSKGFIAQSDHPQALGSALTHPNITTDYSEALLELITPVTREVDELLTSLQEIHQFVHANLPAGESLWAGSMPSLLDGDESIRIAEYGESNLGKIKHVYRRGLAYRYGRIMQSIAGVHFNFSLGDDFWRAYQEVLAQSAPLQEFKSESYFSLIRNFRRWSWLLMYLFGASPALDRSFLNGRDHKLDQFGTDTLGLPHATSLRMSDLGYQNNAQSSLKICFNHLSTYVKTLYDATHTPFPRYEAIGLQRDGEYIQLNANLLQIENEYYNTIRPKRVTQSGEKPIQALKRRGIEYIEVRCLDLDPFSPIGVSESQIRFLDAFLLTCLLSDSAKIVDEECSIIEENFLTAVSRGRATDVELVRLLQNDYVQGGLQEWASRILEQVELCARELDAIKGGDSYAVAVRDARAKVNDPSLTPSARTYAAVSNGQSYVDWTLAMSQAHHQTLIANPLSPERMQHYVRAGEQSWADERALREADNLSFDAYLKQYLTYV
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
Protein: Y2508_MYCS2
Sequence: MGMSSLTRAELGALGEEVAVEHLAALGLKTLARNWRCRYGELDIIAEDAATGTVVFVEVKTRSGDGFGGLAEAVTPQKVRRIRRLAAIWLAAQDAHWAVLRIDVIGVRVGRSRDPEIVHLAGVG
What are the official names of this protein?
UPF0102 protein MSMEG_2508/MSMEI_2448.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: FRQ_NEUCR
Sequence: MADSGDKSQGMRPPPFDSRGHPLPRRASPDKSITLENHRLARDTSSRVTSSSALGVTESQPQLKSSPTRRNSSGESEPTNWFNQSNRNPAAAFHDESHIMEVDPPFYQKETDSSNEESRYPPGRNPVHPPGGVQLPGFRPVAAHSSAADDYRSVIDDLTVENKRLKEELKRYKQFGSDVMRKEKLFEIKVHGLPRRKKRELEATLRDFAASLGDSSESTSQRRKTGRHGTAVHSSGVSLSKHDSSSSSRSRPVDSAYNSMSTGRSSHAPHSSGPSLGRPSLTRAKSVGTQKVENYLRDTPDGLLPHHIVMTDKEKKKLVVRRLEQLFTGKISGRNMQRNQSMPSMDAPLAPEGTNMAPPRPPPEGLREACIQLQDGDNPRKNRSSKDNGSASNSGGDQTELGGTGTGSGDGSGSGGRTGNNTSPPGAIAPDQRPTRPRDLDPDRVQIPSENMDYIRHLGLVSPEFLQGSRTSYQDVAPDAEGWVYLNLLCNLAQLHMVNVTPSFIRQAVSEKSTKFQLSADGRKIRWRGGTDGTKFSSDSSEDKSQQSPMTEDTEDGSDKNGRRKKRKTQQASSEIGRFGPSRSPSDTFHYKPMFVHRNSSSIETSLEESMSQGSEDAVDESNMGNSKWDFSGSGTTQQRRKRRYDGAIVYYTGAPFCTDLSGDPGDMSPTAQMTAGREVEGSGSGDEVEHVLQRTLSGSSLPIRPLSDDRARVAEVLDFDPGNPPELVADDGSSPNDEDFVFPWCEDPAKVRIQPIAKEVMEPSGLGGVLPDDHFVMLVTTRRVVRPILQRQLSRSTTSEDTAEFIAERLAAIRTSSPLPPRSHRLTVAPLQVEYVSGQFRRLNPAPLPPPAIFYPPFSTDSSWDDGDDLASDDEEVEEVEEDSYSEGQISRRANPHFSDNNTYMRKDDLAFDTETDVRMDSDDNRLSDSGHNMRAMMPRAEAVDGDDSPLAAVTGKEVDMLHTGSSVATAGGAESGYSSSMEDVSSS
What is the function of this protein?
Circadian clock component involved in the generation of biological rhythms, in particular in rhythm stability, period length, and temperature compensation.  Oscillates in abundance with a daily peak early in the morning.  Behaves as a negative element in circadian transcriptional loop.  May bind to wc-2 protein.  The complex frq-wc-2 may turn off the expression of frq.
What are the official names of this protein?
Frequency clock protein.
What is the protein family that this protein belongs to?
Belongs to the FRQ family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NOP4_YEAST
Sequence: MEETIENVEVPSSNVSKQNDDGLDMKTLFVRSIPQDVTDEQLADFFSNFAPIKHAVVVKDTNKRSRGFGFVSFAVEDDTKEALAKARKTKFNGHILRVDIAKRRDRSKKTSEVVEKSTPESSEKITGQNNEDEDDADGEDSMLKGKPKLIIRNMPWSCRDPVKLKKIFGRYGTVVEATIPRKRDGKLCGFAFVTMKKISNCRIALENTKDLKIDGRKVAVDFAVQKNRWEDYKKAQPEMNDKDDNESGNEDAEENHDDEEDENEEEDRQVDQASKNKESKRKAQNKREDFSVFVRNVPYDATEESLAPHFSKFGSVKYALPVIDKSTGLAKGTAFVAFKDQYTYNECIKNAPAAGSTSLLIGDDVMPEYVYEGRVLSITPTLVREDAGRMAEKNAAKRKEALGKAPGEKDRRNLYLLNEGRVVEGSKMADLLTNTDMEIREKSYKLRVEQLKKNPSLHLSMTRLAIRNLPRAMNDKALKALARKAVVEFATEVKNKERHPLSKEEIIRSTKEKYKFMGPDEIEAQKKKDKKSGVVKQAKVIMEVKGSTAGRSRGYGFVEFRDHKNALMGLRWLNCHAVTSDEILEGLNDDEKKQVDNDLGKGRRLCVEFAIENSNVVKRRREQLKQARTKRTRPDNEDTGDVGESENKKPKKEEATTPTNPDDKKMGDDIKRIIGFKRKRKHAKK
What is the function of this protein?
Required for 60S ribosomal subunit synthesis.  Probably involved in the processing of 27S rRNA to produce mature 25S rRNA.
What are the official names of this protein?
Nucleolar protein 4, Nucleolar protein NOP77.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: CIPKB_ORYSJ
Sequence: MMDGRSILMGRYEVGKQLGQGTFAKVYYARNLTTGQAVAIKMINKDKVMKVGLMEQIKREISIMRLVKHPNVLQLFEVMASKSKIYFVLEYAKGGELFNKIAKEGKLSEDSARRYFHQLINAVDYCHSRGVYHRDLKPENLLLDENENLKVSDFGLSALAESKRQDGLLHTTCGTPAYVAPEVLSRKGYDGAKADVWSCGVILFVLVAGYLPFHDPNLIEMYRKICRADFRCPRYFSAELKDLIHKILDSDPSTRISIPRIKRSTWYRKPVEINAKNSEAATTNSISSGVATTSGSAECSTSEENQGSLSLPNLNAFDIISLSTGFNLSGFFEDTHGHQEERFTTRQPVTTVLGKLKELAKRLKLKVKKKDNGVLRLAAPKEGKKGFLELDAEIFEVTPSFLLVELKKTNGDTMEYRKLVKEDIRPALKDIVWVWQGDEHLNSQSILQGEQQQSPLPPELPQDQLQPSLPQQEKQDMPEPPLLPQVPQEEVQTSIPAEQTKN
What is the function of this protein?
CIPK serine-threonine protein kinases interact with CBL proteins.  Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner (By similarity).
What are the official names of this protein?
CBL-interacting protein kinase 11, OsCIPK11.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.