PharMolix/UniProtQA huggingface dataset:
Protein: CK024_RAT
Sequence: MWTALVLVWISSVPLSRSHTVPAVPRHLVTNKWPRAGKQNLSGDAVPRADNTSTLRAATVPPAPVTLTTGTWAATLNSTRVTAETTPHGTNTSTPTTREGTADSVTSRILAAPTSSSPSSVRQTLPTTIAGLPSLSTPRAEVPRTNASVSPRTAIATTVAPHTGTPTTGTVTAVSTVTPASGTVTAAVGTVTPAAGTVTAAVGTVTPAAGTVTAAVGTVTPAAVGTVTAAVGTVTSAAGTINTSDPHARTLSPAKSTPTNTSSRNPIPTSGAQTQGTTIQVTTDQPVHSTAGRPTPSPSNTTLEPNTPKSVASTSSAVVTTTQVQTKEPSASTVPVLPTSMSPEVEATSPTTQPSPLLPTQGTGGPGILLTTEQVGTKATAGTASAGPTSRSSGDVKVPTTASCQLSTQGQYLVVTTDPLTPSLVNKMFLLVVLIVGVTLFIAVLMMFALQAYESYKKKDYTQVDYLINGMYADSEM
What are the official names of this protein?
Uncharacterized protein C11orf24 homolog.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Note=Cycles to the plasma membrane via endosomes in a pH sensitive manner. Associated with Rab6-positive vesicles (By similarity).
Protein: PLPL8_MOUSE
Sequence: MSINLTLDIYIYFLNNARSLCGKQRSKQLHFVCSKQYWRMNHVNVHREFHTSKKSCKWNRSEAHCSKHWHSPSNHGLHFGIVRLSTSAPKGLTKVSIHMSRIKSTLNSVSKAIFGSQNEMVTRLAQFKPSSRILRKVSDKGWLKQKNVKQAVESLKNYSDKSAGKNSLAEQKSYFADKEEDSGKHSLFHYTYGITTRFGESFSVLANHINSYFKSKGKMSQTKEDKQLQDKPDLEERKSSSPGPDTVADRPDSESPLEVKDKLSSPTQMPEAHPVSAKQSIANFLSRPTEGVQALVGGYIGGLVPKLKSDPKSPPEEQEVSAKTEQAVNKDKKAEEKKRVLLQQEKIIARVSIDNRTRALVQALRRTADPKLCITRVEELTFHLLEFPEGKGVAIKEKIIPYLLRLRQVKDETLQAAVREILALIGYVDPVKGRGIRILTIDGGGTRGVVALQTLRKLVELTQKPIHQLFDYICGVSTGAILAFMLGLFHMPLDECEELYRKLGSDVFTQNVIVGTVKMSWSHAFYDSNTWEKILKDRIGSALMIETARNPACPKVAAISTIVNRGQTPKAFVFRNYGHFPGTNSHYLGGCQYKMWQAIRASSAAPGYFAEYALGSDLHQDGGLLLNNPSALALHECKCIWPDTPLECIVSLGTGRYESDVRNTSTYTSLKTKLSNVISSATDTEEVHIMLDGLLPSDTYFRFNPVICENIPLDESRDEKLDQLQLEGMKYIERNDQKMKKVAKILSQEKTTLQKINDWIKLKSDMYEGLPFFSKL
What is the function of this protein?
Calcium-independent and membrane-bound phospholipase, that catalyzes the esterolytic cleavage of fatty acids from glycerophospholipids to yield free fatty acids and lysophospholipids, hence regulating membrane physical properties and the release of lipid second messengers and growth factors (PubMed:17923475, PubMed:28442572).  Hydrolyzes phosphatidylethanolamine, phosphatidylcholine and probably phosphatidylinositol with a possible preference for the former.  Has also a broad substrate specificity in terms of fatty acid moieties, hydrolyzing saturated and mono-unsaturated fatty acids at nearly equal rates from either the sn-1 or sn-2 position in diacyl phosphatidylcholine.  However, has a weak activity toward polyunsaturated fatty acids at the sn-2 position, and thereby favors the production of 2-arachidonoyl lysophosphatidylcholine, a key branch point metabolite in eicosanoid signaling.  On the other hand, can produce arachidonic acid from the sn-1 position of diacyl phospholipid and from the sn-2 position of arachidonate-containing plasmalogen substrates.  Therefore, plays an important role in the mobilization of arachidonic acid in response to cellular stimuli and the generation of lipid second messengers.  Can also hydrolyze lysophosphatidylcholine (By similarity).  In the mitochondrial compartment, catalyzes the hydrolysis and release of oxidized aliphatic chains from cardiolipin and integrates mitochondrial bioenergetics and signaling.  It is essential for maintaining efficient bioenergetic mitochondrial function through tailoring mitochondrial membrane lipid metabolism and composition (PubMed:17923475, PubMed:28442572).
What are the official names of this protein?
Calcium-independent phospholipase A2-gamma, Intracellular membrane-associated calcium-independent phospholipase A2 gamma, iPLA2-gamma, Patatin-like phospholipase domain-containing protein 8.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein. Peroxisome membrane; Single-pass membrane protein.
Protein: CYF_CHLSU
Sequence: MIFKPQSFLKAIVLSMTITFAFNMSAPIASAYPIFAQQNYENPREANGRIVCANCHLAQKPVELEVPQAVLPDTVFEAIIQIPYDTQVKQVLANGKKGDLNVGMVLILPEGFELAPADRIPEEMKKKVGNLYYQPYSPDKKNILVVGPVPGKQYSEMVVPLLSPDPATNKNVSYLKYPIYVGGNRGRGQVYPDGSKSNNTVYNSPVSGTITEILKLEGKKGGYTISITKADGVVLTEKIPGGPEVIVKEGQAIIADQPLTNNPNVGGFGQKDVEVVLQNPVRIQGLLAFFACILLAQILLVVKKKQFEKVQLAEMNF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome f family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CALR_MAIZE
Sequence: MAIRKGSSYAVAALLALASVAAVAGEVFFQEKFEDGWESRWVKSEWKKDENMAGEWNHTSGKWNGDAEDKGIQTSEDYRFYAISAEYPEFSNKDKTLVLQFSVKHEQKLDCGGGYVKLLGGDVDQKTLGGDTSYSIISRPDISRYSTKKVHTILTKDGKNHLIKKDVPCQTDQLTHVYTFIIRPDATYSILIDNEEKHTGSIYEHWDILPPKKIKDPEAKKPEDWDDKEYIPDPEDKKPEGYDDIPKEIPDPDAKKPEDWDDEEDGEWTAPTIPNPEYKGPWKQKKIKNPNYQGKWKAPMIDNPDFKDDPYIYAFDSLKYIGIELWQVKSGTLFDNIIITDDPALAKTFAEETWGKHKEAEKAAFDEAEKKKEEEDAAKGGDDEDDDLEDEEDDEKADEDKADSDAEDGKDSDDEKHDEL
What is the function of this protein?
Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle.  This lectin may interact transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER (By similarity).
What are the official names of this protein?
Calreticulin.
What is the protein family that this protein belongs to?
Belongs to the calreticulin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: LYRM1_TAEGU
Sequence: MTPATRQEVLGLYRKVFRIAKNWQSASGQIEETMREKEYIRNEARTLFRKNKNVTDPNLIKQCIEECEARIEIGLHYNIPYPRPIHLPPMGLAHKQGRTLRHQERLRKISKPIYLKSHDEVS
What are the official names of this protein?
LYR motif-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family.
Protein: Y401_STAAN
Sequence: MGYSKRFALYISILILIVMVAGCGKSDETKEDSKEEQIKKSFAKTLDMYPIKNLEDLYDKEGYRDGEFKKGDKGTWVLYSAIVSQPKGESLKSRGMILKLDRNKRTAKGSYIIRELKEDKNHDVQKNEKKYPVKLVNNRIVLVKDVKDKKLKNEIESFELFSQYGNFNHFDRNEITNISYNPNAPNYSAEYKMKKNDRNIQQLKKRFNLKTSKTPKLLFKGSGDIKGSSVGYKEIEIIFSRSKEEAFIMLTALSSFQVTK
What are the official names of this protein?
Uncharacterized lipoprotein SA0401.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal tandem lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: IBPB_SALCH
Sequence: MRNYDLSPLLRQWIGFDKLANALQNSGESQSFPPYNIEKSDDNHYRITLALAGFRQEDLDIQLEGTRLTVKGTPEQPENEPKWLHQGLVMQPFSLSFTLAENMEVSGATFTNGLLHIDLTRNEPETIAPQRIAINERSALNS
What is the function of this protein?
Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress.  Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE.  Its activity is ATP-independent.
What are the official names of this protein?
Small heat shock protein IbpB, 16 kDa heat shock protein B.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPDH_BACFN
Sequence: MKKVRAAIVGYGNIGRYVLEALQAAPDFEIAGVVRRAGAENKPAELNDYAVVKDIKELQGVDVAILCTPTRSVEKYAKEILAMGINTVDSFDIHTGIVDLRRELGACAKEHGAVSIISAGWDPGSDSIVRTMLEAIAPKGITYTNFGPGMSMGHTVAVKAIDGVKAALSMTIPTGTGIHRRMVYIELKDGYKFEEVAAAIKSDAYFVNDETHVKQVPSVDALLDMGHGVNLTRKGVSGKTQNQLFEFNMRINNPALTAQVLVCVARASMKQQPGCYTMVEVPVIDLLPGDREEWIGHLV
What is the function of this protein?
Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.  Probably plays a role in lysine biosynthesis.  Exhibits a high substrate specificity for meso-2,6-diaminopimelate (m-DAP), since the activity with L,L-2,6-diaminopimelate is less than 5% of the activity observed with m-DAP.  Can use NAD(+) only very poorly since the activity observed in the presence of NAD(+) is about 14% of that with NADP(+).
What are the official names of this protein?
Meso-diaminopimelate D-dehydrogenase, DAPDH, Meso-DAP dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate dehydrogenase family.
Protein: DXR_EHRRG
Sequence: MKTVSIFGSTGAIGQMIIDVILASSDSYQVKALVAKSNVQLLAFQAKVVNAEMVVIADVGLYKELKDLLFGTNVKISVGDVGMQMAASLNVDYVMMAIVGIAALVPMVYLISAGVKVIALANKESVVCGGTLLFNLAREKNVNIIPVDSEHNAIFQILHSNDRENIDKITITGSGGALLYMDHDQMRNITVQETIKHPVWKMGKKISIDSATMVNKSLEIIEAYHLFSVKSEKLDVIIHPEAIVHGIVSYVDGACIAFMSVPDMKISIMYTLSWPNRMSMLYKKLNLASYHQLTFMKPDINKFPGIRLGFEILRTSNIHANSIIFNTANEVAVDAFLNRKIGFLDIVNVIYSTLDMVDCLHINSLSDILECDSIARRVASDIICKLN
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: YCF36_GUITH
Sequence: MNCPVPENQLPINEYNKLTSAWDFSWACKIGKLYYKFLLKMQLCLFLFFCICLNFLDSKYETGLYSLILSTLFICLICLRTYLGFRYIYVRLLKSALPYEESSWYDGQVWVKNINYLIKDRLVADYTVLPILSRLKISFTINFSFLICLLLRFIF
What are the official names of this protein?
Uncharacterized protein ycf36.
What is the protein family that this protein belongs to?
Belongs to the ycf36 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: BPT_ACIAD
Sequence: MKSYQPKSLLNDLQYYITPPHDCSYLDNKSARMVFLDPIHRIDVVTLSELSRVGFRRSGDFVYRPECHLCRQCLSCRVPVHDFNMNSLQKKAWKRNQDLRMSIVPTHAATSVHYQLYERYINERHADGDMFPPSLDQFEKFLVHSCTESFFLELWKDDRLICVSTCDLMDDGLSAVYTFFDPDENRRSLGVFAILKQLEYVKSIDLDYLYLGYWVPHSQKMNYKSQYIPLELLLDGQWRRLNRALSQEEISQLGESLMTILPSEWNSMIIK
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA2_XENLA
Sequence: MSAENESPGLPNGGACCASATGHFLLVGNKVTVVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINQNAIAFIGNGVVIHLPGLFEEAEKNLKKGQGLAGWEKRLCISDRAHIVFDFHQAADGIQEQQRQEQAGKNLGTTKKGIGPVYSSKAARSGLRMCDLVSDFNEFSQRFKLLAKQYKSMYPSLEIDIDGELKKLQDYADRVKPMVKDGVYYIYEALHGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPQSIGDVYGVVKAYTTRVGIGAFPTEQNNDIGEMLQTRGHEYGVTTGRKRRCGWLDLVLLRYAHMINGFTALALTKLDILDVFSEIKVGVSYKIDGKNIPHFPANQEVLNKVEVEYETLPGWNKDTSNVRTFEELPENAKKYVQFIKEELGIPIKWIGVGKSRESMIQLF
What is the function of this protein?
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase isozyme 2, AMPSase 2, AdSS 2, Adenylosuccinate synthetase, acidic isozyme, Adenylosuccinate synthetase, liver isozyme, L-type adenylosuccinate synthetase, IMP--aspartate ligase 2.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion.
Protein: EPAB2_MOUSE
Sequence: MEPYLSNELFPPPTEAWLQTVSSDPEAQGWGAWGRTEKTSLVPRAGSRAGSDKEAEENEDASFLLSLLEPENLAKSPVFNQELEAIKLKLWAMEHAEAQPEPPCVQRKATEEERAEVRQLLSPETVDCFFSRTSKENVEADHRSVFVGNVDYGGSAAELEAYFSPCGEIHRVTILCDKFSGHPKGYAYIEFASHRSVKAAVGLDESTFRGRVIKVLPKRTNFPGISSTDRGGLRTHSGNRAAFLHGSLHRKARLRAHGRSRGHGGAPQWFSPY
What is the function of this protein?
Binds the poly(A) tail of mRNA.
What are the official names of this protein?
Embryonic polyadenylate-binding protein 2, Embryonic poly(A)-binding protein 2, ePABP-2, ePABP2, Embryonic poly(A)-binding protein type II, Poly(A)-binding protein nuclear-like 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNG_YERPA
Sequence: MSPSLTWHDVIGQEKEQPYFKDTLAYVAAERRAGKTIYPPQKDIFNAFRLTELDQVKVVILGQDPYHGPNQAHGLSFSVLPGVPAPPSLGNIYKELVTDIPGFQRPNHGFLQSWAEQGVLLLNTVLTVEAGKAHSHANLGWETFTDKVIAALNEHREGVIFMLWGSHAQKKGRIINTERHYILKAPHPSPLSAHRGFLGCKHFSQANQLLQQQNQQPIDWQPKLPAVE
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAH10_PONAB
Sequence: MEIVWEVLFLLQANFIVCISAQQNSPKIHEGWWAYKEVVQGSFVPVPSFWGLVNSAWNLCSVGKRQSPVNIETSHMIFDPFLTPLRINTGGRKVSGTMYNTGRHVSLRLDKEHLVNISGGPMTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLVVVSIFIKVSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSMTIPPCYETASWIIMNKPVYITRMQMHSLRLLSQNQPSQIFLSMSDNFRPVQPLNNRCIRTNINFSLQGKDCPNNRAQKLQYRVNEWLLK
What is the function of this protein?
Does not have a catalytic activity.
What are the official names of this protein?
Carbonic anhydrase-related protein 10.
What is the protein family that this protein belongs to?
Belongs to the alpha-carbonic anhydrase family.
Protein: MNME_SALAR
Sequence: MSHNDTIVAQATPPGRGGVGILRISGLNAKKVAQTVLGKLPKPRYADYLPFKDADGATLDQGIALWFPGPNSFTGEDVLELQGHGGPVILDLLLKRILTIPGVRIARPGEFSERAFLNDKLDLAQAEAIADLIDASSEQAARSALNSLQGAFSARVNHLVEALTHLRIYVEAAIDFPDEEIDFLSDGKIEAQLNGVIADLDAVRAEARQGSLLREGMKVVIAGRPNAGKSSLLNALAGREAAIVTDIAGTTRDVLREHIHIDGMPLHVIDTAGLRDASDEVERIGIERAWQEIEQADRVLFMVDGTTTDAVDPGDIWPDFIARLPKNLPITVVRNKADITGEMLGISEVNGHSLVRLSARTGEGVDVLRNHLKQSMGFDTNMEGGFLARRRHLQALAEAAEHLEQGKAQLLGAWAGELLAEELRLAQQSLSEITGEFTSDDLLGRIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_FRAAA
Sequence: MGQKVNPHGFRLGITSEFTSRWYADKQYKAYVGEDVKIRKMMSRGMERAGISRVDIERTQGRLRVDIHTARPGIVIGRRGAEADRIRGDLEKLTGKQVQLNILEVKNPEVDAQLVAQGVAEQLSSRVSFRRAMRKAMQTAMKGGAKGIRVQCSGRLGGAEMSRSEFYREGRVPLHTLRADIDYGFYEARTNFGRIGVKVWIYKGDIVQSRAEREAQEALQRQTRRDRPRRGPRSGSSGTTQGGTDAGRAAARSERRGRGGNAPAAETAASEAGATESTAPESTAPESTAPESTAPESTAPESTAPETTAPEAASSPAPAAESTAPATAASESAATPAAAATPGTPEKAEE
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: GR36B_DROME
Sequence: MVDWVVLLLKAVHIYCYLIGLSNFEFDCRTGRVFKSRRCTIYAFMANIFILITIIYNFTAHGDTNLLFQSANKLHEYVIIIMSGLKIVAGLITVLNRWLQRGQMMQLVKDVIRLYMINPQLKSMIRWGILLKAFISFAIELLQVTLSVDALDRQGTAEMMGLLVKLCVSFIMNLAISQHFLVILLIRAQYRIMNAKLRMVIEESRRLSFLQLRNGAFMTRCCYLSDQLEDIGEVQSQLQSMVGQLDEVFGMQGLMAYSEYYLSIVGTSYMSYSIYKYGPHNLKLSAKTSIIVCILITLFYLDALVNCNNMLRVLDHHKDFLGLLEERTVFASSLDIRLEESFESLQLQLARNPLKINVMGMFPITRGSTAAMCASVIVNSIFLIQFDMEFF
What is the function of this protein?
Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
What are the official names of this protein?
Putative gustatory receptor 36b.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr22e subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS7_SALHS
Sequence: MPRRRVIGQRKILPDPKFGSELLAKFVNILMVDGKKSTAESIVYSALETLAQRSGKSELEAFEVALENVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALAMRWIVEAARKRGDKSMALRLANELSDAADNKGTAVKKREDVHRMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: ROCA_STAAC
Sequence: MVVEFKNEPGYDFSVQENVDMFKKALKDVEKELGQDIPLVINGEKIFKDDKIKSINPADTSQVIANASKATKQDVEDAFKAANEAYKSWKTWSANDRAELMLRVSAIIRRRKAEIAAIMVYEAGKPWDEAVGDAAEGIDFIEYYARSMMDLAQGKPVLDREGEHNKYFYKSIGTGVTIPPWNFPFAIMAGTTLAPVVAGNTVLLKPAEDTPYIAYKLMEILEEAGLPKGVVNFVPGDPKEIGDYLVDHKDTHFVTFTGSRATGTRIYERSAVVQEGQNFLKRVIAEMGGKDAIVVDENIDTDMAAEAIVTSAFGFSGQKCSACSRAIVHKDVYDEVLEKSIKLTKELTLGNTVDNTYMGPVINKKQFDKIKNYIEIGKEEGKLEQGGGTDDSKGYFVEPTIISGLKSKDRIMQEEIFGPVVGFVKVNDFDEAIEVANDTDYGLTGAVITNNREHWIKAVNEFDVGNLYLNRGCTSAVVGYHPFGGFKMSGTDAKTGSPDYLLHFLEQKVVSEMF
What are the official names of this protein?
1-pyrroline-5-carboxylate dehydrogenase, P5C dehydrogenase, L-glutamate gamma-semialdehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. RocA subfamily.
Protein: NUSG_STRP3
Sequence: MLDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIPTQTVNVEKNGQTKEIEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPTPLLEEEIRAILLSMGQTIDVFDTNIKEGDVVQIIDGAFMGQEGRVVEIENNKVKLMLNMFGSETVAEVELYQIAEL
What is the function of this protein?
Participates in transcription elongation, termination and antitermination.
What are the official names of this protein?
Transcription termination/antitermination protein NusG.
What is the protein family that this protein belongs to?
Belongs to the NusG family.
Protein: CTAA_DINSH
Sequence: MSKKRSIFEEVSEAQPKAQPVQPGVIDRAARTGARGAVRVWLMMLFGLVVIMIAVGGLTRLTDSGLSITEWAPIAGAIPPLSAEDWAREFDLYRAIPEYQLQNKGMTLAEFQFIYWWEWGHRQLGRVIGLVWALGFFGFLVTRKIPPGWTGRLFLLGVLGGLQGAIGWWMVASGLTGTMLDVASYRLATHLGLAFFILGLIAWYIMVLGRPERDLLQARRSGEAGLVTGANWLMGLAAVQILLGALVAGIDAGRTYTDWPLMAGGFLPLNMWELEPIWRNFFEDPGLVQFNHRMVGYLLLLVGLYVWWRSRRSAHVTTKRAFDWVAVILFGQMVLGIVTVLNAAPWTWAIAHQFGAVVTICLILRARFRARYPVATSLRGAVA
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RNI_AERHY
Sequence: MKKIVVLLGMLLAPWFSSAVQAKGEAGEFDYYAMALSWSPEHCAIKPADRDQCSRQLGFVLHGLWPQYQRGYPSSCTRERLDPAMEQEFAGLYPSRFLYRHEWEKHGTCSGLSQHDFHQLASDLRQKREDPGRLSVSCRAAAQKPLPAQGGSGQCQRLAGPGQHHGGLRRRWRFLREVYICLNKEGTDAVTCSDEMQKRELPSCGQPDFLLRTVR
What is the function of this protein?
One of the few RNases that cleave the phosphodiester bond between any two nucleotide.  Shows a preference for adenylic acid.
What are the official names of this protein?
Ribonuclease.
What is the protein family that this protein belongs to?
Belongs to the RNase T2 family.
What are the subcellular locations of this protein?
Periplasm. Cytoplasm. Note=An RNase I-like form (periplasmic) and RNase I*-like form (cytoplasmic) appear to be isoforms apparently encoded by the same gene. The cytoplasmic form is less active towards natural polymer RNA.
Protein: DGTL1_SHESH
Sequence: MTESLWHERRLTEEKKRRNDHRSPYQRDRARILHSAAFRRLQAKTQVLGVGMNDFYRTRLTHSLEVSQIGTGIRAQLKQKRPEFDHLFDSMSLIESLCLAHDIGHPPFGHGGEVALNYMMRDHGGFEGNGQTFRILTGLEPYTEYYGMNLCRRTLLGILKYPAPYSSLYRASGNKPVNNIRQLKPSQWTPVKGIFDDDSGILDWVLEPLNGSDRERFLSHRDLGANKHLRTQFKSLDCSVMELADDIAYAVHDLEDAIVMGIVTPSQWQQDVASKLTLSHDAWIKEEFTNIGQNLFSHQHHLRKDAIGTLVNGFVTAIDIVEDRAFTDPLLRFNAGLDTSFSEALEVLKQFVYKYVIRKPEIQMLEYKGQQIVMELFEAFESDPERLLPTHTQERWRESHTKGLNSHRVIADYISGMTDEFAARLHQHLFNPKAGSMIELNGEL
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 2 subfamily.
Protein: NUDC_PSESM
Sequence: MTRPQRWTTAVLDVEADGGLAVVQGDQGFLLDSNGALFPRSWLRALDLPVQSEHGIGYFDGEPVYLLVLQHSVVVEGCAWQGLRQFMLEGDFAVFQMLGYAAQVATWAREHRFCGACGRATVQIAGERAMYCEHDNLRLYPRISPSMIVLVTRGDEVLLARSPRFVSGMYSALAGFVEPGESAEDCVHREVMEEVQVRIKNLKYMGSQCWPFPHSMMLGFHAQYAGGDIVPQVDEIEDARWFHIDDLPPLPANRSIARYLIEAYLAERSGAPEPVLPG
What is the function of this protein?
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.  The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing.  Has preference for mRNAs with a 5'-end purine.  Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.
What are the official names of this protein?
NAD-capped RNA hydrolase NudC, DeNADding enzyme NudC, NADH pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudC subfamily.
Protein: EFTU_LISMH
Sequence: MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLAKKGFADAQAYDQIDGAPEERERGITISTAHVEYQTDNRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLSRQVGVPYIVVFMNKCDMVDDEELLELVEMEIRDLLTEYEFPGDDIPVIKGSALKALQGEADWEAKIDELMEAVDSYIPTPERDTDKPFMMPVEDVFSITGRGTVATGRVERGQVKVGDEVEVIGIEEESKKVVVTGVEMFRKLLDYAEAGDNIGALLRGVAREDIQRGQVLAKPGSITPHTNFKAETYVLTKEEGGRHTPFFNNYRPQFYFRTTDVTGIVTLPEGTEMVMPGDNIELAVELIAPIAIEDGTKFSIREGGRTVGAGVVSNISK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ICAR_STAAW
Sequence: MKDKIIDNAITLFSEKGYDGTTLDDIAKSVNIKKASLYYHFDSKKSIYEQSVKCCFDYLNNIIMMNQNKSNYSIDALYQFLFEFIFDIEERYIRMYVQLSNTPEEFSGNIYGQIQDLNQSLSKEIAKFYDESKIKMTKEDFQNLILLFLESWYLKASFSQKFGAVEESKSQFKDEVYSLLNIFLKK
What is the function of this protein?
Represses transcription of the icaADBC operon necessary for biofilm production.
What are the official names of this protein?
Biofilm operon icaADBC HTH-type negative transcriptional regulator IcaR, Intercellular adhesion protein R.
Protein: ARGE_SALEP
Sequence: MKNVLPPFIEIYRALIATPSISATEESLDQSNASLITLLAGWFSDLGFNVEVQPVPGTRNKFNMLASTGHGAGGLLLTGHTDTVPFDDGRWTRDPFTLTEHDNKLYGLGTADMKGFFAFILDALRDVDVTKLKKPLYILATADEETSMAGARYFSETTALRPDCAIIGEPTSLQPIRAHKGHISNVVRVLGQSGHSSDPARGVNAIELMHDAIGHIMQLRDSLKARYHYEAFTVPYPTLNLGHIHGGDASNRICACCELHMDIRPLPGMTLNDLNGLLNDALAPVSERWPGRLTVAELHPPIPGYECPPDHQLVEVVEKLLGTKTDVVNYCTEAPFMQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELITQVVHHFCWH
What is the function of this protein?
Catalyzes the hydrolysis of the amide bond of N(2)-acetylated L-amino acids.  Cleaves the acetyl group from N-acetyl-L-ornithine to form L-ornithine, an intermediate in L-arginine biosynthesis pathway, and a branchpoint in the synthesis of polyamines.
What are the official names of this protein?
Acetylornithine deacetylase, AO, Acetylornithinase, N-acetylornithinase, NAO.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. ArgE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.