PharMolix/UniProtQA huggingface dataset:
Protein: PDXB_PSEPG
Sequence: MLIVADENIPLLDAFFQGFGEIRRYPGRSLDAASVKDADILLVRSVTKVDRQLLEGSRVRFVGTCTIGTDHLDLDYFAQASISWSSAPGCNARGVVDYVLGSLLTLAELDGVALAERVYGVVGAGEVGGRLVRVLHGLGWKVLVCDPLRQAAEGGDYVSLETIVQQCDVISLHTPLQRGGEHPTWHLLGPAQLAQLRPGAWLVNASRGPVVDNIALRELLLDREDVHAVLDVWEGEPQVDLQLADLCTLASPHIAGYSLDGRQRGTAQIYQALCRFLGVDEQVQLADLLPRPALAQVELDASTDPAWALATLCRAVYDPRRDDADFRRSLSDDPQLQRAAFDQLRKHYPPRREIEGLAVRLRGESPQLAQLVSALGGALV
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSPP1_HUMAN
Sequence: MLFPLQVAAVTSSVRDDPLEHCVSPRTRARSPEICKMADNLDEFIEEQKARLAEDKAELESDPPYMEMKGKLSAKLSENSKILISMAKENIPPNSQQTRGSLGIDYGLSLPLGEDYERKKHKLKEELRQDYRRYLTQGITQGKRKKNFLSTSETDPSTLGVSLPIGERLSAKERLKLERNKEYNQFLRGKEESSEKFRQVEKSTEPKSQRNKKPIGQVKPDLTSQIQTSCENSEGPRKDVLTPSEAYEELLNQRRLEEDRYRQLDDEIELRNRRIIKKANEEVGISNLKHQRFASKAGIPDRRFHRFNEDRVFDRRYHRPDQDPEVSEEMDERFRYESDFDRRLSRVYTNDRMHRNKRGNMPPMEHDGDVIEQSNIRISSAENKSAPDNETSKSANQDTCSPFAGMLFGGEDRELIQRRKEKYRLELLEQMAEQQRNKRREKDLELRVAASGAQDPEKSPDRLKQFSVAPRHFEEMIPPERPRIAFQTPLPPLSAPSVPPIPSVHPVPSQNEDLRSGLSSALGEMVSPRIAPLPPPPLLPPLATNYRTPYDDAYYFYGSRNTFDPSLAYYGSGMMGVQPAAYVSAPVTHQLAQPVVNTVGQNELKITSDQVINSGLIFEDKPKPSKQSLQSYQEALQQQIREREERRKKEREEKEEYEAKLEAEMRTYNPWGKGGGGAPLRDAKGNLITDLNRMHRQNIDAYHNPDARTYEDKRAVVSLDPNLATSNAENLEDAANKSSGHMQTQSSPFARGNVFGEPPTELQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEKKREKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPPSVDSIIRSFIHESSMSRAQSPPVPARKNQLRAEEEKKNVIMELSEMRKQLRSEERRLQERLLHMDSDDEIPIRKKERNPMDIFDMARHRLQAPVRRQSPKGLDAATFQNVHDFNELKDRDSETRVDLKFMYLDPPRDHHTLEIQQQALLREQQKRLNRIKMQEGAKVDLDAIPSAKVREQRMPRDDTSDFLKNSLLESDSAFIGAYGETYPAIEDDVLPPPSQLPSARERRRNKWKGLDIDSSRPNVAPDGLSLKSISSVNVDELRVRNEERMRRLNEFHNKPINTDDESSLVDPDDIMKHIGDDGSNSVATEPWLRPGTSETLKRFMAEQLNQEQQQIPGKPGTFTWQGLSTAHG
What is the function of this protein?
May play a role in cell-cycle-dependent microtubule organization.
What are the official names of this protein?
Centrosome and spindle pole-associated protein 1.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=Associated with mitotic spindles.
Protein: IF3_MACCJ
Sequence: MSTIAKDQTQINDRIRAKELRLIGHDGEQLGVKTKFEAIEIAERVNLDVVLVAPNAKPPVAKIMDYGKFKFEQQKKEKEARKKQKVVTVKEIRLSPTIEDHDFNTKLKNARKFLEKEDKVKVSIRFRGRAITHKEFGQRVLEKFAEECKDLATVEQKPKMDGRSMFLMLAPIVDKKQN
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_LEPBA
Sequence: MSIVKSKIRTIPDYPKPGILFRDITSLLIDPEGFQLTIGMFVERYQNAKLNKIAAIDARGFIPGAALAFQLGVGFVPIRKKGKLPGNTISESYALEYGVDHVEIHTDAIVPGDKVLIMDDLIATGGTLEASIKLIQNLKGQIHECSTIINLPDLGGAKRIKDTYGIDVFSICEFEGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y358_METJA
Sequence: MTFDLLKELKRIYKHFENIDLEQFERDLIECGFGKIKPGPLATDEVLTEEDIAKYREIIMKSQTCNVNTHNQIVIKINLKEINADNKMYCKFRKGYKFKEDIKVGEESSYIITLQQDSLHICNNYEVA
What are the official names of this protein?
Uncharacterized protein MJ0358.
Protein: URE3_BURA4
Sequence: MKLTPREKDKLLIFTAALLAERRRARGLKLNYPEAVAFITAALMEAARDGKTVAEVMHYGTTLLTRDDVMDGVPEMIPDIQVEATFPDGTKLVTVHHPIP
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASNA_HAEIN
Sequence: MKKTFILQQQEISFVKNTFTQNLIEQLGIIEVQGPILSQVGNGMQDNLSGIEKAVQVNVKCIPNAVFEVVHSLAKWKRHTLARFNFKEDEGLFVHMKALRPDEDSLDPTHSVYVDQWDWEKVIPEGRRNFAYLKETVNSIYRAIRLTELAVEARFDIPSILPKQITFVHSEDLVKRYPDLSSKERENAICKEYGAVFLIGIGGKLSDGKPHDGRAPDYDDWTTESENGYKGLNGDILVWNDQLGKAFELSSMGIRVDESALRLQVGLTGDEDHLKMDWHQDLLNGKLPLTIGGGIGQSRLAMLLLRKKHIGEVQSSVWPKEMLEEFSNIL
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CASP2_VIGUN
Sequence: MSTTIDIPESSKVVKGKGVVAAPLRPGGWKKGVAIMDFILRLGAIAAALGAAATMGTSDQTLPFFTQFFQFEASYDSFTTFQFFVITMALVGGYLVLSLPFSVVAIIRPHAVGPRLFLIILDTVFLTLATASAASAAAVVYLAHNGDQDTNWLAICNQFGDFCAQTSSAVVSSFVAVVVFVLLIVMSALAMGKP
What is the function of this protein?
Regulates membrane-cell wall junctions and localized cell wall deposition.  Required for establishment of the Casparian strip membrane domain (CSD) and the subsequent formation of Casparian strips, a cell wall modification of the root endodermis that determines an apoplastic barrier between the intraorganismal apoplasm and the extraorganismal apoplasm and prevents lateral diffusion (By similarity).
What are the official names of this protein?
Casparian strip membrane protein 2, VuCASP2.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Very restricted localization following a belt shape within the plasma membrane which coincides with the position of the Casparian strip membrane domain in the root endodermis.
Protein: KLDC2_HUMAN
Sequence: MADGNEDLRADDLPGPAFESYESMELACPAERSGHVAVSDGRHMFVWGGYKSNQVRGLYDFYLPREELWIYNMETGRWKKINTEGDVPPSMSGSCAVCVDRVLYLFGGHHSRGNTNKFYMLDSRSTDRVLQWERIDCQGIPPSSKDKLGVWVYKNKLIFFGGYGYLPEDKVLGTFEFDETSFWNSSHPRGWNDHVHILDTETFTWSQPITTGKAPSPRAAHACATVGNRGFVFGGRYRDARMNDLHYLNLDTWEWNELIPQGICPVGRSWHSLTPVSSDHLFLFGGFTTDKQPLSDAWTYCISKNEWIQFNHPYTEKPRLWHTACASDEGEVIVFGGCANNLLVHHRAAHSNEILIFSVQPKSLVRLSLEAVICFKEMLANSWNCLPKHLLHSVNQRFGSNNTSGS
What is the function of this protein?
Substrate-recognition component of a Cul2-RING (CRL2) E3 ubiquitin-protein ligase complex of the DesCEND (destruction via C-end degrons) pathway, which recognizes a C-degron located at the extreme C terminus of target proteins, leading to their ubiquitination and degradation (PubMed:29779948, PubMed:29775578, PubMed:30526872).  The C-degron recognized by the DesCEND pathway is usually a motif of less than ten residues and can be present in full-length proteins, truncated proteins or proteolytically cleaved forms (PubMed:29779948, PubMed:29775578, PubMed:30526872).  The CRL2(KLHDC2) complex specifically recognizes proteins with a diglycine (Gly-Gly) at the C-terminus, leading to their ubiquitination and degradation (PubMed:29779948, PubMed:29775578, PubMed:30526872).  The CRL2(KLHDC2) complex mediates ubiquitination and degradation of truncated SELENOK and SELENOS selenoproteins produced by failed UGA/Sec decoding, which end with a diglycine (PubMed:26138980, PubMed:30526872).  The CRL2(KLHDC2) complex also recognizes proteolytically cleaved proteins ending with Gly-Gly, such as the N-terminal fragment of USP1, leading to their degradation (PubMed:29775578, PubMed:30526872).  May also act as an indirect repressor of CREB3-mediated transcription by interfering with CREB3-DNA-binding (PubMed:11384994).
What are the official names of this protein?
Kelch domain-containing protein 2, Hepatocellular carcinoma-associated antigen 33, Host cell factor homolog LCP, Host cell factor-like protein 1, HCLP-1.
Protein: RNPH_YERP3
Sequence: MRPADRAAQQVRPLTLTRNYTKHAEGSVLVEFGDTKVLCTATVEEGVPRFLKGQGQGWITAEYGMLPRSTHSRNAREAAKGKQGGRTLEIQRLIARSLRAAVDLKKLGEFTITLDCDVLQADGGTRTASISGACVALADALNKLVASGKLKANPMKGLVAAVSVGIVKGEALCDLEYVEDSAAETDMNVVMMEDGRMIEVQGTAEGEPFSHEELLALLDLARGGIETIFQAQKAALES
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: RS10_SOLM1
Sequence: MVSMQNDRIRIKLKAYDYRILDKAVAEIVDTARNTGAGVAGPIPLPTDIHKVTVNRSVHVDKKSREQFEMRVHKRLLDIMEPTQQTVDALGKLSLPAGVDVEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: DIT9_BPNF
Sequence: MAYVPLSGSDVRIFSDVPFSNDYKNTRWFTSADAQYSYFNAKPRVHVINECNFVGLKEGTPHIKVNKRIDDLYNACYMIFRNTQYSNKWFYCFVTRLEYVNSGVTNLYFEIDVIQTWMFDFKFQPSYIVREHQTMWDANKEPLTNTIDEGLNYGSEYDIVAVEQYRPYGDLMFMVCISKSKMHATAGETFKAGEIAANINGAPQPLSYYVHPFYEDGSSPKVTIGSNEVQVAKPTDFLKNMFTQEHAVKNIVSLYVTDYIGLNIHYDESAKTMSLKDSMFEHTQISDDKHPNVNTIYLKEIKEYEEKTIDTGYKFASFANNEQSKLLMYPYCVTTITDFKGNQIDIKNEYVNGSNLKIQVRGSLGVSNKVTYGVKDYNADSTLSGSQKLTASLQHSLINNNPNDVAIINDYLSAYLQGNKNSLENQKDSILFNGVMGMLGNGIGAAASAATGSAVGVASSATGMVSSAGNAVLQIQGMQAKQADIANTPPQLVKMGGNTAYDYGNGYRGVYVIKKQIKEEYRNILSDFFKKYGYKTNLVKMPNLRTRKSYNYVQTKDCNITGNLNNEDLQKIRTIFDSGITLWHADPVGDYTLNNEVI
What is the function of this protein?
Distal (knob) tail protein that plugs the end of the tube before DNA ejection and forms a channel perforating the host membrane during ejection.
What are the official names of this protein?
Tail knob protein gp9, Distal tube protein, Gene product 9, gp9, Protein p9, Tail protein.
What is the protein family that this protein belongs to?
Belongs to the picovirinae distal tube protein family.
What are the subcellular locations of this protein?
Virion. Note=Present in 6 copies in the virion. Located at the tip of the tail and constitutes most of the tail knob.
Protein: YACG_YERPN
Sequence: MESEQIQVNCPTCGKVVIWGEQSPFRPFCCKRCQLIDLGEWADEEKRIPSDTELSDSDEWSEEDPLKH
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: GATB_BRUSI
Sequence: MSIIDTRTPEPKRFISGATGDWEVVIGMEVHAQVTSESKLFSGASTAFGAEPNSNVSLVDAAMPGMLPVINLECVRQAVRTGIGLNAQINLKSVFDRKNYFYPDLPQGYQISQFKQPIVGEGKIMISVGPDNKGQFEDVEIGIERLHLEQDAGKSMHDQHPTMSYVDLNRSGVALMEIVSKPDLRSSDEARAYLTKLRTIVRYLGTCDGNMDEGSMRADVNVSVRRPGGEFGTRCEIKNVNSIRFVGQAIEYEARRQIAILEDGGVIDQETRLFDPVKGETRSMRSKEEAHDYRYFPDPDLLPLEFDQAFVDALAAKLPELPDVKKQRLVETLGISVYDASILVTEKAIADYYEAVAEGRDGKAAANWVINDLLGALNKAGKDIEESPISPAQLGAIIDLIKEGTISGKIAKDLFEIVWNEGGDPKKLVEERGMKQVTDTGAIEKAVDDVIAANPDKVEQAKAKAKPTLAGWFVGQVMKATGGKANPQAVNELVKSKLGIEE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: UTP4_MOUSE
Sequence: MGEFKVHRVRFFNYVPSGIRCVAYNNQSNRLAVSRTDGTVEIYNLSANYFQEKFFPGHESRGTEALCWAGGQRLFSAGLNGEILEYDLQALNIKYTLDAFGGPIWSMTASPSGSQLLVGCEDGSVKLFEVTPEKIQFARNFDRQKSRILSLCWHPAGTHVAAGSLDYISVFDVKSGSIIRKMVLDRQHLGVTKSRCIVWGVAFLSDGTVISVDSVGKVQLWDSATGTLVKSHLVANADVQSIAVADQEDSFVVGTAEGTVFHFQLVSMTSNSSEKQWVRTKPFQHHTHDVRAVAHSPTALISGGTDTHLVIRPLMERVEVKNYDAALRKITFPHRRLISCSKRRQLLLFQFAHHLELWRLGSTSATGKNGDTLPLSKNADHLLHLKTKGPENIICSCVSPCGSWIAYSTASRFFLYRLKYERDNISLQRVSKLPSFLRSALHILFSEDSTKLLVASNQGSLHIVHLSEGSFKHLHTFQPQSGTVEAMCLLAVSPDGNWLAASGTSAGVHVYDLHHLKLHCTVPAYNFPVTALAIAPNTNNLVIAHSDQQVFEFSIPEKQYTEWSRSLQKQGFHQLWLQRDTPITHISFHPKRPMHILLHDAYMFCIIDKSLPLPNEKTVLYNPLPPKNESDVFLRRTTHGFKMSKIYKPLLFMDLLDERTLVAVERPLDDIIAQLPPPIKKKKFGT
What is the function of this protein?
Ribosome biogenesis factor.  Involved in nucleolar processing of pre-18S ribosomal RNA.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted d Involved in SSU pre-rRNA processing at sites A', A0, 1 and 2b.  Required for optimal pre-ribosomal RNA transcription by RNA polymerase.  May be a transcriptional regulator.
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 4 homolog, Cirhin, Testis-expressed gene 292 protein.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Chromosome. Note=Found predominantly at the fibrillar center.
Protein: RS16_RUEPO
Sequence: MAMKIRLARGGSKKRPFYRIVAADSRMPRDGRFIEKLGTYNPLLPKDSEERVKMDVERVQYWLSQGAQTTDRVARMLEAAGVVGKTERSNPNKAVPGKKAKERAEEKAAKAAAATEAAAEE
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: NUOC_POLAQ
Sequence: MSDRLVHLAANLEKVLGKRVQSIEIALGEVTVVVNADTYFESAMLMRDDPSLAFEQLIDLCGVDYQDFRDGAWNGQRFGVVSHLLSLEHNWRLRVRVFAPDDSYPLVASITPVWSSANWFEREAFDLYGIIFEGHEDLRRILTDYGFIGHPFRKDFPISGNVEMRYDPELKRVVYQPVTIEAREITPRIVREEQYGDPV
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: FZD7A_XENLA
Sequence: MSSTVSLLFCCLFLQLCPSAQQYHGEKGISVPDHGFCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLEQAIPPCRSLCERARQGCEALMNKFGFQWPERLRCENFPVHGAGEICVGQNTSDNSPSGPTARPSPYLPDSITFQPHPHRDFTCPRQLKVPPYLAYRFLGEKDCGAPCEPGKANGLMYFKEEEVRFARLWVGIWAILCCISTLFTVLTYLVDMRRFSYPERPIIFLSGCYFMVAVAYTAGFLLEERAVCVERFSEDSYRTVAQGTKKEGCTILFMILYFFGMASSIWWVILSLTWFLSAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQVDGDVLSGVCYVGINSVDSLRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVMYTVPATIVLACYFYEQAFRDTWEKTWLVQTCKGYAVPCPNYNFAPMSPDFTVFMIKYLMTMIVGITSSFWIWSGKTLQSWRRFYHRLSNGSKGETAV
What is the function of this protein?
Receptor for Wnt proteins.  Acts in both canonical and non-canonical Wnt pathways.  Although different papers report differing Wnt preferences, wnt5a, wnt8b and wnt11 have been proposed as synergists.  In the canonical Wnt pathway, acts via beta-catenin to promote the expression of the dorsal genes siamois, twin and nodal3 and to establish the dorsal axis of the embryo and induce dorsal mesoderm formation.  In a non-canonical Wnt/planar cell polarity (PCP) pathway, acts with sdc4 and dvl2/dsh to regulate convergent extension cell movements during gastrulation.  Triggers phosphorylation of dvl2/dsh and its translocation to the plasma membrane.  In a third branch of Wnt signaling, acts in a non-canonical pathway via trimeric G proteins, and independently of dvl2/dsh, to recruit protein kinase C (PKC) to the membrane and thus activate PKC.  PKC signaling controls cell sorting and tissue separation during gastrulation.
What are the official names of this protein?
Frizzled-7-A, Fz-7-A, Xfz7-A.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor Fz/Smo family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Note=Associated to the plasma membrane in the presence of FZD7 and phosphatidylinositol 4,5-bisphosphate (PIP2). Localized in recycling endosomes in other conditions.
Protein: SYFB_BORGP
Sequence: MPKVEIYKNLFLDKIGKNFTNLEISELLEPFKAEFDGFDENSGKIKIEFNDTNRPDLWSYTGLARQIKTYLFGEIPYYDFFSKKGDFKKCYGEILVDNKMSQIRPFIFGFLAKGLIINDRMLEALIQFQEKLCQSYGQKRRRVAMGMYNSNFIKFPISYVASSPNHKFVPLGMDCELSLLEINEKHPKGLEYSYIVKNFDKYPLLLDNNNNVVSYPPIINSNNIGSLKVGDTELFVEVTGIDFEATLLALSIVACDFYDMGFEILPVKTVFKDPFGLDFEELVCPYYFQEEVEFDVKNVNRLLGNNLTLERICLNLKKMGVSSYSRDFKNYIVPPFYRNDFLHEVDVIEDVMIGEGLASFYPELPKAFTIGRLSALEEFSRNVRNLMMGMGFQEMIYNYMGSRKDFIDRMNINDQNFLKVSNPMTENYEYIRASIIPNLLKSESVSSNFPYPHKIFEVGKVALKNLDAAEGTSTFTNLAFLMSGKEISFNEINSIVATLFYYLNIEIILRESKATFYINGRGADILIEGFNVGSFGEISPYVLNNFGIFIPCSVFEVNINKLVSQS
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UT2_RAT
Sequence: MSDHPLKEMSDNNRSPPLPEPLSSRYKLYESELSSPTWPSSSQDTHPALPLLEMPEEKDLRSSDEDSHIVKIEKPNERSKRRESELPRRASAGRGAFSLFQAVSYLTGDMKECKNWLKDKPLVLQFLDWVLRGAAQVMFVNNPLSGLIIFIGLLIQNPWWTIAGALGTVVSTLAALALSQDRSAIASGLHGYNGMLVGLLVAVFSEKLDYYWWLLFPVTFASMACPVISSALSTVFAKWDLPVFTLPFNIALTLYLAATGHYNLFFPTTLVKPASSAPNITWSEIEMPLLLQTIPVGVGQVYGCDNPWTGGVILVALFISSPLICLHAAIGSIVGLLAALTVATPFETIYTGLWSYNCVLSCVAIGGMFYVLTWQTHLLALVCALFCAYTGAALSNMMAVVGVPPGTWAFCLSTLTFLLLTSNNPGIHKLPLSKVTYPEANRIYFLTAKRSDEQKPPNGGGGEQSHGGGQRKAEEGSETVFPRRKSVFHIEWSSIRRRSKVFGKSEHQERQTKEPLPYLYRKPTVELLDLNTMEESSEIKVETNTTRTTWIQSSMIAGGKRVSKALSYITGEMKECGEGLKDKSPVFQFLDWVLRGTSQVMFVNNPLSGILIVLGLFVQNPWWAISGCLGTIMSTLTALILSQDKSAIAAGLHGYNGVLVGLLMAVFSDKGNYYWWLLLPVIVMSMTCPILSSALSTVFSKWDLPVFTLPFNIAVTLYLAATGHYNLFFPTKLLQPAVTTPNITWSDVQVPLLLRAIPVGIGQVYGCDNPWTGGIFLVALFVSSPLICLHAAIGSTIGMLAALSIATPFDSIYFGLCGFNSTLACIAIGGMFYVITWQTHLLAIACALFAAYLGAALANMLSVFGLPPCTWPFCLSALTFLLLTTNNPGIYKLPLSKVTYPEANRIYFLSQEKNRRASMITKYQAYDVS
What is the function of this protein?
Mediates the transport of urea driven by a concentration gradient across the cell membrane of the kidney inner medullary collecting duct which is critical to the urinary concentrating mechanism.
What are the official names of this protein?
Urea transporter 2, Solute carrier family 14 member 2, Urea transporter, kidney.
What is the protein family that this protein belongs to?
Belongs to the urea transporter family.
What are the subcellular locations of this protein?
[Isoform 1]: Apical cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Vasopressin increases expression in the cell membrane.
Protein: RHLB_PECAS
Sequence: MSKTHLTEQKFSDFALHPQVIEALESKGFHYCTPIQALALPLTLSGRDVAGQAQTGTGKTLAFLASTFHYLLSHPANAERQTNQPRALIMAPTRELAVQIHSDAEALSHLTGLKLGLAYGGDGYDKQLKVLENGVDILVGTTGRLIDYAKQNHINLGAIQVVVLDEADRMYDLGFIKDIRWLFRRMPATSQRLNMLFSATLSYRVRELAFEQMNNAEYVEVEPEQKTGHRITEELFYPSNEEKMRLLQTLLEEEWPDRCIIFANTKHRCEDVWGHLAADGHRVGLLTGDVAQKKRLRILEEFTQGSIDILVATDVAARGLHIPSVTHVFNYDLPDDCEDYVHRIGRTGRAGQSGFSISLACEEYALNLPAIETYIGHGIPLSKYNSDALMNDLPAPKRLTRPPRSNNGPRRHNSAPRRSGAPRNNRKRAD
What is the function of this protein?
DEAD-box RNA helicase involved in RNA degradation.  Has RNA-dependent ATPase activity and unwinds double-stranded RNA.
What are the official names of this protein?
ATP-dependent RNA helicase RhlB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. RhlB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUCC_JANSC
Sequence: MNIHEYQAKALLAQYGAPVSDGRVVTKAEDAKTAAGEMDGPLWVVKAQIHAGGRGKGKFKEADAGEAGGVRLAKSAQEAADEAKKMLGRTLVTHQTGPVGKQVNRIYIEDGSGIETEMYLALLVDRQSSRISFVCSTEGGMDIEEVAASTPEKILSFSVDPATGYQPYHGRRVAFSLGLEGQQVKQCVKLMGQLFTAFQEKDMEMLEINPLIVTDEGNLKVLDAKVSFDGNAVYRHADVASLRDETEEDPKELAASKFDLNYIALDGEIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGGGATKEKVTEAFKIITSDPQVKGIFVNIFGGIMRCDIIAEGVIAAVKEVGLQMPLVVRLEGTNVEKGKEIINNSGLDVIAADDLKDGAQKIVKAVKG
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: RL31B_PSYWF
Sequence: MRKDIHPEYQEVLFHDTNADVFFLTRSTAKTKATREYEGKEYPYYPLDISSASHPFYTGEQRKTSNEGRVASFNKRFGAFGGRSKAKKTDAE
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: PORIM_MOUSE
Sequence: MALCARAALLLGVLQVLALLGAAQDPTDAQGSASGNHSVLTSNINITENTNQTMSVVSNQTSEMQSTAKPSVLPKTTTLITVKPATIVKISTPGVLPHVTPTASKSTPNASASPNSTHTSASMTTPAHSSLLTTVTVSATTHPTKGKGSKFDAGSFVGGIVLTLGVLSILYIGCKMYYSRRGIRYRSIDEHDAII
What is the function of this protein?
Implicated in oncotic cell death, characterized by cell swelling, organelle swelling, vacuolization and increased membrane permeability.
What are the official names of this protein?
Porimin, Transmembrane protein 123.
What is the protein family that this protein belongs to?
Belongs to the CD164 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: OPALI_PONAB
Sequence: MSFSLNFTLPANTTSSPVTGGKETDCGPSLGLAAGIPSLVATALLVALLFTLIHRRRSSIEAMEESDRPCEISEIDDSPKISENPRRSPTHEKNTMGAQEAHIYVKTAAGSEEPVHDRYRPTIEMERRRGLWWLVPRLSLE
What is the function of this protein?
Central nervous system-specific myelin protein that increase myelin genes expression during oligodendrocyte differentiation.  Promotes oligodendrocyte terminal differentiation.
What are the official names of this protein?
Opalin, Oligodendrocytic myelin paranodal and inner loop protein, Transmembrane protein 10.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=In the CNS, enriched in the myelin paranodal and inner loop membranes, but not that of the PNS. Enriched in the leading edge of extending processes.