PharMolix/UniProtQA huggingface dataset:
Protein: DXR_PSEP1
Sequence: MGCDVSRPQRITVLGATGSIGLSTLDVIARHPDRYQAFALTGYSRIDELLALCVRHRPAFAVVPSTEAAVRLRAGLAAAGCTTEVLEGEAGLCQVASAAEVDAVMAAIVGAAGLRPTLAAVEAGKKVLLANKEALVMSGALFMEAVRQKGAVLLPIDSEHNAIFQCMPGDYARGLSAVGVRRILLTASGGPFRETPVEALLDVTPEQACAHPNWSMGRKISVDSASMMNKGLELIEACWLFDAVPSKVEVVVHPQSVIHSLVDYVDGSVLAQLGNPDMRTPIANALAWPERIDSGVAPLDLFAIARLDFQAPDEQRFPCLRLARQAAEAGNSAPAVLNAANEVAVEAFLERRIRFPEIAGMIEQVLDQEPVVPLPSLDAVFAADQRARELSREWLRRHGR
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: ISPG_BRUA4
Sequence: MSSEAVSYFSHPFPRRQSVGVSVGGVIVGGSAPVVVQSMTNTDTADVDSTVAQVAALHRAGSEIVRITVDRDESAAAVPKIRERLERLGHDVPLVGDFHYIGHKLLADHPACAEALAKYRINPGNVGFKDKKDKQFADIVEMAIRYDKPVRIGVNWGSLDQELLTTLMDRNQDAGAPLSAQEVMREAIVQSALISANLAEEIGLGRDKIILSAKVSQVQDLIAVYTMLAQRSNHALHLGLTEAGMGTKGIVASSAAMGILLQQGIGDTIRISLTPEPGGDRTREVQVSQELLQTMGFRQFIPIVAACPGCGRTTSTVFQELAQTIQDDIRRNMPVWREKYPGVEALSVAVMGCIVNGPGESKHADIGISLPGTGETPSAPVFVDGKKVTTLRGPAIAEDFQKMVADYIENRFGLDQKIAAGQN
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: FAEH_ECOLX
Sequence: MKITHHYKSLLSAIISVALFYSAAPHADILDGGEIQFNGFVTDDAPKWTWQISSPDQTWAVDTADARTENGQLVFDLSDKGPLPFLEGYLYEVAERGGPGFTPFITFSSNGRPFAVKEGSDTSVQRFRASVPVRDPETGNVSGQLSFTLNQGMAVSTGKQEEGASTPSGMSLVSGQSVTDVQSGSLPQGLKNRLSALLLMNKGFGNGMSAVDNGQVITQGVLADGRVMNLAAAYASAVSDFELRLPAEGTPARWQAGLNVTVTVQ
What is the function of this protein?
K88 minor fimbrial subunit, plays an essential role in the biogenesis of the K88 fimbriae.  Fimbriae (also called pili), are polar filaments radiating from the surface of the bacterium to a length of 0. 5-1. 5 micrometers and numbering 100-300 per cell.  They enable bacteria to colonize the epithelium of specific host organs.
What are the official names of this protein?
K88 minor fimbrial subunit FaeH.
What is the protein family that this protein belongs to?
Belongs to the fimbrial K88 protein family.
What are the subcellular locations of this protein?
Fimbrium. Note=Located in or along the K88 fimbrial structure.
Protein: RNP1_METBU
Sequence: MEALPSNLIFHELIGLYAEVFESTNPKLINICGRVIDETRNMLIIETEDTHEKMVPKNGTTFVFHLPSSSADHDQRVKIFGTLLLSQPENRVKNIRKIRMR
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 1, RNase P component 1, Rpp29.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WFD12_LEMCA
Sequence: MRSYSFWFLTAFLVFATLALGEAVKGGKEKWGNCPAEKGSCIKSGPSQCHADNDCPGDKKCCFLSCSFKCVSPDRIRKEGGNEDEDVSRSSPEPGGEPRPPGSSPSTSILSYYAVSFPPPGIGQMAPVPQGAESWNVGQEASPQKEWS
What is the function of this protein?
Antibacterial protein.  Putative acid-stable proteinase inhibitor (By similarity).
What are the official names of this protein?
WAP four-disulfide core domain protein 12.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS6_PROM9
Sequence: MVALRLIPCLDVAHGRVVKGVNFVNLRDSGDPVELACRYSDEGADELVFLDIRASVENRNTLVDLVSRTAKSVKIPFTVGGGIDSVSSINDLLRAGADKVSLNSSAVRNPDLISKSSREFGNQCIVIAIDAKRKVNKTDEWEVYVKGGRENTGIDVLSWAKKVEELGAGEILLTSMDGDGTQNGYDLHLTESVANIVNIPVIASGGAGCLEDIYDVFNEGRASAALLASLLHDKKLSLREIKTFLLERKLPIRPYE
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHST5_HUMAN
Sequence: MGMRARVPKVAHSTRRPPAARMWLPRFSSKTVTVLLLAQTTCLLLFIISRPGPSSPAGGEDRVHVLVLSSWRSGSSFLGQLFSQHPDVFYLMEPAWHVWTTLSQGSAATLHMAVRDLMRSIFLCDMDVFDAYMPQSRNLSAFFNWATSRALCSPPACSAFPRGTISKQDVCKTLCTRQPFSLAREACRSYSHVVLKEVRFFNLQVLYPLLSDPALNLRIVHLVRDPRAVLRSREAAGPILARDNGIVLGTNGKWVEADPHLRLIREVCRSHVRIAEAATLKPPPFLRGRYRLVRFEDLAREPLAEIRALYAFTGLTLTPQLEAWIHNITHGSGIGKPIEAFHTSSRNARNVSQAWRHALPFTKILRVQEVCAGALQLLGYRPVYSADQQRDLTLDLVLPRGPDHFSWASPD
What is the function of this protein?
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues and O-linked sugars of mucin-type acceptors.  Acts on the non-reducing terminal GlcNAc of short carbohydrate substrates.  However, it does not transfer sulfate to longer carbohydrate substrates that have poly-N-acetyllactosamine structures.  Has no activity toward keratan.  Not involved in generating HEV-expressed ligands for SELL.  Its substrate specificity may be influenced by its subcellular location.
What are the official names of this protein?
Carbohydrate sulfotransferase 5, Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 4-alpha, GST4-alpha, Intestinal N-acetylglucosamine-6-O-sulfotransferase, I-GlcNAc6ST, Intestinal GlcNAc-6-sulfotransferase, hIGn6ST, N-acetylglucosamine 6-O-sulfotransferase 3, GlcNAc6ST-3, Gn6st-3.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein. Note=Golgi membrane, early secretory pathway.
Protein: TATA_BACAH
Sequence: MFSNIGFPGLILILVAVLILFGPKKLPEIGKALGETLKEFKKSTKELTDDAFQEKEKKEKM
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: Y070_XANCP
Sequence: MDKNRIEGAAKQVKGSVKEAIGRVTGDKSTELEGAAEKNIGKVQRKAGELADDVRDATKSTR
What are the official names of this protein?
UPF0337 protein XCC0070.
What is the protein family that this protein belongs to?
Belongs to the UPF0337 (CsbD) family.
Protein: CDC6N_HALMA
Sequence: MIEQADEESVFRNRNLVEPDTIIDRDRIVGRDDQLRTVVSNLRKVLNENRPPNLLLYGPAGTGKSLIFDAVARQIRDISKNRGYEFGTLRINCQNLRSLDEAVYALVREAAHDLNEEIGVARHGVSTSTKYDRLYDLLDEGYDSVVFVLDEIDLLLGRRSSSSEPAYSDLIYQLSRASIESIDIQVSVAALTNDPEFMNNLDARAESSFNPRDIPFSDYDANQLQEILRNREDAFIQDALSEDVIPLTSAFAAQSHGDARKAIDLLRKAGDVANENGDLTVTENHVREAQEDVETDRSLKLVEGLTTQKKISLYATAAVAEFGKSGSTTASSRVAFPVYQFLTDVLDADGRTRETFNNYVREVGTYGQLDHERKSLGGKQGGGMYLMYEFKRDPGEIKKRLEQDERIADLSHHEDGLNRVIQAQKRNFAED
What is the function of this protein?
Involved in regulation of DNA replication.
What are the official names of this protein?
ORC1-type DNA replication protein 14.
What is the protein family that this protein belongs to?
Belongs to the CDC6/cdc18 family.
Protein: PRSA_CLOP1
Sequence: MVSVKKIVASALVGVLMFSAVGCNMVEKTQAAIDKTTVATVNGEKITLGEVDSHLKGVFAQMKSQYGDKYMDDPQVAQQILQQRQSVVQGLVTDKVLGIEADKLGIKPSEEEIKKKVDEQFENIKKGMGDNFDKALEAEGYTEDTFKDVIKNQVINQAVQDYIIKDVKVTDEDAQKYYDENKQQFVAKDSGVLTKHLLFENEEEAQKAYDEIQSGKTTFNDLFTKYENNKSENKKPIAENLGVVPAENSGLVQEFVDGLKPLKEGEISKPIKTQFGYHIIQAGATYEKGAQLPFDDVKSQIIQILKQQKDSEKFKADMDQWKKDLNVKVYDDKLQEGLKISK
What is the function of this protein?
Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.
What are the official names of this protein?
Foldase protein PrsA.
What is the protein family that this protein belongs to?
Belongs to the PrsA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: AMPA_HERAR
Sequence: MDFSIKPLDAKSTIASIKTGCIAVAVFEDKKLSAAAQALDQKGGISAALKSGDISGKAGSTLLLRGVSGVAAERVLLVGLGKEDPVSEKDFSSAVQAVARAFTSLGATEAVIALPLDAVAARDAAWSIRCTILNTRDASYRFDSLKSKKEPAPAGVKKIVFAVSAASTAIAKDAIAQAVAQANGIDLTKDLGNLPANVCTPTYLANTAKKMAKEFKLQVEVLDRKQLQALKMGSFLSVTNGSVEPPKFIVLKHMGGKAKDAPVVLVGKGITFDSGGISLKPGAAMDEMKYDMGGAASVLGTMRAIAELKLKLNVIVVIPTCENMPSGSATKPGDIVTSMSGQTIEVLNTDAEGRLVLCDALTYVERFKPAAVIDVATLTGACITALGHHNSGLFTRSDDAHDALANELLAAGKASGDTAWRMPIEDSYQEQLKSNFADMANIGGPAGGAVTAACFLERYTKKYTWAHLDIAGTAWKSGAAKGSTGRPVPLLTSFLIQRAQTAR
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_CLOB1
Sequence: MEFFNILQSACNDVNLDFNDKKYNQLISYKNLIQEWNKKINLTAIVEDDEIIKKHFIDCIKIFKSSPIGEAKSLIDIGTGAGFPGIPIKILKEDIEITLLDSLQKRINFLNTVIGELQLKNIQCLHGRAEDYAQEIQHRQKYDIAVSRAVANLAVLSEFCIPFVEKGGYFIAMKGPSVEEEITAATKSIEILGGKIEDIIKIDIEDTDLKHNLVIIKKVKETGKRYPRKPGIIKKNPLK
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAM_YERPE
Sequence: MQDWDPDLYRQFEAERTRPATDLLAHITITSPQFISDLGCGPGNSTELLHRRFPDAQLVGIDHSQAMLASAQQRLPHCTFIEADIHQWRPSQPQNLIYANASLQWLTDHPHLFPSLLSQLAPRGVLAVQMPDNLDQPSHRAMREVAENGPWQQTLQEAGATRAKVLSANHYYDLLAPHAERVDIWRTTYYHPMPSAQAIVDWLRATGLRPYLAPLTEAMQLAFLQNYLAIIDKAYPARTDGRRLLAFPRLFIVAHAQR
What is the function of this protein?
Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
What are the official names of this protein?
Trans-aconitate 2-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Tam family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNME_SHEFN
Sequence: MTTDTIVAQATAPGRGGVGIIRISGDLATNVATAIIGHVPKTRYAEYCDFNNADGQVIDQGIALFFKGPNSFTGEDVLELQGHGGQIVLDMLIKRVMEIDGIRIARPGEFSEQAFMNDKLDLTQAEAIADLIDATSEQAAKSALQSLQGEFSKEVHELVDQVTNLRLYVEAAIDFPDEEVDFLSDGKIANALYKIISKLDTVQASAKQGSIIREGMKVVIAGRPNAGKSSLLNALAGKESAIVTEIAGTTRDVLREHIHLDGMPLHIIDTAGLRDTLDTVEQIGIERAWAEIASADRVLFMVDGTTTDAVNPHEIWPDFIDRLPAKLGVTVVRNKADLTGETLDKTEEQGSCVYRISAKTGLGIDELKQHLKSLMGYQSNLEGGFIARRRHLEALELAANHLQLGKEQLEVYLAGELLAEELRMTQMALSEITGKFTSDDLLGKIFGSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NMT_ASPFU
Sequence: MSDSKDRKGKAPEGQSSEKKDGAVNITPQMAESLLENNPALRNETAGMDKDKAAEAMRKMNIAELLTGLSVSGKNQKDMASYKFWQTQPVPRFDETSTDTGGPIKIIDPEKVSKEPDALLEGFEWATLDLTNETELQELWDLLTYHYVEDDNAMFRFRYSQSFLHWALMSPGWKKEWHVGVRATKSRKLVASICGVPTEINVRNQKLKVVEINFLCIHKKLRSKRLTPVLIKEITRRCYLNGIYQAIYTAGVVLPTPVSSCRYYHRPLDWLKLYEVGFSPLPAGSTKARQITKNHLPSTTSTPGLRPMEPKDIDTVHDLLQRYLSRFALNQAFTREEVDHWLVHKPETVKEQVVWAYVVEDPETHKITDFFSFYNLESTVIQNPKHDNVRAAYLYYYATETAFTNNMKALKERLLMLMNDALILAKKAHFDVFNALTLHDNPLFLEQLKFGAGDGQLHFYLYNYRTAPVPGGVNEKNLPDEKRMGGVGIVML
What is the function of this protein?
Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
What are the official names of this protein?
Glycylpeptide N-tetradecanoyltransferase, Myristoyl-CoA:protein N-myristoyltransferase, NMT, Peptide N-myristoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAZ_DESVV
Sequence: MLFRGRSHRSLDPKGRLMLPPEFRDILLSRSEEGKLVLTSFDGCVVGYPYPDWVEFEDKFNRLKNPSRKMRDFRRLVIGGAEEMTADPQGRVRVSRSHMDYAGLTKDVVLVGQGSRFEIWDQSKFDAIVAQDFDDVTEELAESGIDFCF
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: PT111_YEAST
Sequence: MLQRRFISSSGIKRLLHRESNKVMHTVFFKVRYYSTELIKKKHKEDIEDWVKAQLKDSSTISGVYESRNKLDWMDSITKSPSSLDILKNQYNIVKDKDFGILWKQKFESADPDILMTIISLSTNQKVLFSIQQLLILINSLHFLKRDYDIGQIYTTYEQFTPLLASHTDKGTYGQFIEIMLVVQHNLHHFDVCETLFAEYIKYCKVKPQMISLGLNSFIRSNNTQLAVEFYTQAITNPDTFPITEKQLFEFLRCMERYLDMSSMKHIFYLWLKVKCGDEQSSSTNLPSFKTLAIIHRMLLRFSNTDELNDFLTNPVVLSTGYTSSVQFELIEFCHSLYCIKGDRTKSIDDSILMERVDKFITRLNNNISTRKELYMSVVQAYVSTNNFENLKVILEKIQRDNDISIDGSFHLCISRYFVNTNQFEGLFKYYRSVVKTTDGKTRLRPAFIQQLWSCAVNVYPMLAKEITNDLLVTLKRSQYSKCLTWVYTFLQENAHIHTRKINGGEDSSLSGFNAVDFERFEEFKKKVSHNDVYGAELVISNSLKEGIAPQFSFLYSVLALCLRNSLTGLARVVDVILRTRFRYIPLKVDILWLKWEIISNYRSFEKLSAEHLKELEFKLKEFERVHQKELSVQNYLQLTQICFHTRDFKYACYLISQARKNLDTSNNKQWMMYYMTSLKLASRMHESERFSRILKDWNCNHRASLITPGCIRQIKGFMKYFEKRPAYISTAASIDNKEIKDRIDELVLRYVDYKYQGLENMRKLTLFLKEWFDEEISLLKLEQNERKMKLFEENKKEEE
What is the function of this protein?
Required for translation of the mitochondrial gene for cytochrome c oxidase subunit II (COX2).
What are the official names of this protein?
Protein PET111, mitochondrial.
What is the protein family that this protein belongs to?
To yeast YHR160C.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: CY561_BOVIN
Sequence: MEGPASPARAPGALPYYVAFSQLLGLIVVAMTGAWLGMYRGGIAWESALQFNVHPLCMIIGLVFLQGDALLVYRVFRNEAKRTTKVLHGLLHVFAFVIALVGLVAVFEHHRKKGYADLYSLHSWCGILVFALFFAQWLVGFSFFLFPGASFSLRSRYRPQHVFFGAAIFLLSVATALLGLKEALLFELGTKYSMFEPEGVLANVLGLLLATFATVILYILTRADWKRPLQAEEQALSMDFKTLTEGDSPSSQ
What is the function of this protein?
Transmembrane reductase that uses ascorbate as an electron donor in the cytoplasm and transfers electrons across membranes to reduce monodehydro-L-ascorbate radical in the lumen of secretory vesicles (PubMed:3597367, PubMed:1623014, PubMed:18501187).  It is therefore involved the regeneration and homeostasis within secretory vesicles of ascorbate which in turn provides reducing equivalents needed to support the activity of intravesicular enzymes (Probable).
What are the official names of this protein?
Transmembrane ascorbate-dependent reductase CYB561, Chromomembrin B, Cytochrome b-561, Cytochrome b561.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane; Multi-pass membrane protein. Note=Secretory vesicle containing catecholamines and amidated peptides.
Protein: VSP1_DABRR
Sequence: VIGGDECNINEHPFLA
What is the function of this protein?
Snake venom serine protease that may act in the hemostasis system of the prey.
What are the official names of this protein?
Vipera russelli proteinase RVV-V homolog 1, RVV-V 1, Snake venom serine protease, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TBP_THEKO
Sequence: MVDMSNVKLRIENIVASVDLFTDLNLEKVIEICPSSKYNPEEFPGIICRFDDPKVALLIFSSGKLVVTGAKSVDDIKRAVYKLIEMLKKIGAKFTREPQIDIQNMVFSGDIGMEFNLDAVALILPNCEYEPEQFPGVIYRVKEPRAVILLFSSGKIVCSGAKSEQDAWEAVKKLLRELEKYGLIEEEEEW
What is the function of this protein?
General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase.  Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
What are the official names of this protein?
TATA-box-binding protein, Box A-binding protein, BAP, TATA sequence-binding protein, TBP, TATA-box factor.
What is the protein family that this protein belongs to?
Belongs to the TBP family.
Protein: YE88_SCHPO
Sequence: MSSLNSVLPSNACAEIIEGKDKVHNVVILMHGLGDSHKSFANMAKNVPLPNTSYISLRGPYRLPLDFENPGGNWMWGEDVHFDQNGELQSEADFSKSFTMISNLIGNLLSYGILSSRIFFFGFGQGAMVALYSCYKLSTKYQLGGIFSFGGTLPLSITLPNHPFHVPVYLFEKRLHCSCSEYEESRLRKTFKPFHLTCWNRDDKTDMPSSPREWYTFVQSISKHLYIHNTLFEDAIPLTSF
What are the official names of this protein?
Uncharacterized hydrolase C9G1.08c.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.
Protein: CATA_ACIRA
Sequence: TAANVKIFNTEEVQNFINLL
What are the official names of this protein?
Catechol 1,2-dioxygenase, 1,2-CTD.
What is the protein family that this protein belongs to?
Belongs to the intradiol ring-cleavage dioxygenase family.
Protein: LTOR3_BOVIN
Sequence: MADDLKRFLYKKLPSVEGLHAIVVSDRDGVPVIKVANDNAPEHALRPGFLSTFALATDQGSKLGLSKNKSIICYYNTYQVVQFNRLPLVVSFIASSNANTGLIVSLEKELAPLFEELRQVVEVS
What is the function of this protein?
As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids.  Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag.  Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated.  Adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2 (By similarity).
What are the official names of this protein?
Ragulator complex protein LAMTOR3, Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3.
What is the protein family that this protein belongs to?
Belongs to the LAMTOR3 family.
What are the subcellular locations of this protein?
Late endosome membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HUTH_CERSK
Sequence: MEILVPGQATLAQLEAIWREGRRARLAPEARPAVEAAAARVAAAAAGTAPVYGVNTGFGKLASLKIAPADTAQLQRNLILSHCCGVGEPMPPSTARLMMALKLLSLGRGASGVRWKIVALLEGMLAAGVTPVIPAQGSVGASGDLAPLAHMAAVMIGEGEAEVGGRRLPGAAALAHAGLAPVALGPKEGLALINGTQFSTAYALAGLFEGWRAAQAALVISALSTDAIMGSTAPLRPEIHALRGHAGQIEAAATMRALLEGSAIRESHREGDQRVQDPYCIRCQPQVTGAAMDVLRMAAGTLATEANAATDNPLVLSDGRIVSGGNFHAEPVGFAADMIALALSEIGAIAQRRVALMVDPTLSFDLPPFLTPEPGLNSGLMIAEVTTAALMSENKHMAAPTVTDSTPTSANQEDHVSMAAHGARRLGRMVENLAVILGTEAICAAQGVEFRAPLATSAPLGAVLARLRAEVPRLGADRILAPDLAAAARLVRTGALARAAGLPLPAL
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSH_VIBC3
Sequence: MPNRTVPTLEELLTLNKVQQTLRLTEVNQHLESLTAQERVVWGLENLQGNHALSSSFGIQAAVMLHLLTSVKSDIPVVLTDTGYLFPETYQFIDELTERLNLNLKVYSAPVSAAWQEARYGKLWEQGVEGIERYNQINKVEPMRRALDELNIGTWFSGLRREQSQSRASLPILSVQNGVFKFLPVIDWTNKEVHYYLKDNDLPYHPLWEQGYLSVGDTHTTQKWQPGMNEEQTRFFGLKRECGLHEDHNDTHQ
What is the function of this protein?
Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
What are the official names of this protein?
Phosphoadenosine 5'-phosphosulfate reductase, PAPS reductase, 3'-phosphoadenylylsulfate reductase, PAPS reductase, thioredoxin dependent, PAPS sulfotransferase, PAdoPS reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGA27_CANAL
Sequence: MHFTSSLLATLIWFTLPVQSLNTESRTTSNNTISILTNHFQILKDLLPYSKTSKPQIKESRPLIKVSRDGVPINFHRAPAIIMKSNKTDDLVRNSNKTMVLTEIKTITEFATTTVSPTQEFQALQINLNTLSIETSTPTFQSHDFPPITIEDTPKTLEPEESSDALQRDAFDQIKKLEKLVLDLRLEMKEQQKSFNDQLVDIYTARSIVPIYTTHIVTSAIPSYVPKEEVMVSHDSAPIVSRPRTDIPVSQRIDTISKHKMNGKNILNNNPPPNSVLIVPQFQFHERMATKTEVAYMKPKIVWTNFPTTTATSMFDNFILKNLVDETDSEIDSGETELSDDYYYYYSYEDDGKEDDSDEITAQILLSNSELGTKTPNFEDPFEQINIEDNKVISVNTPKTKKPTTTVFGTSTSALSTFESTIFEIPKFFYGSRRKQPSSFKNKNSTIKFDVFDWIFESGTTNEKVHGLVLVSSGVLLGTCLLFIL
What are the official names of this protein?
Predicted GPI-anchored protein 27.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: PHNC_PSEE4
Sequence: MSIRLQEAGLRHGQVQALNNVDLQIGKGERVAIIGPSGAGKSSLLHLMATAVRPSAGQLDLLGEQPWLLTSGARQRLRARVGLVHQAPPLPPRQRVVTAVLAGRLGQWGTLRGLLNLIHPSDVPGAREVLAELGMVDKLFVQCGQLSGGQLQRVGIARALYQQPEVLLTDEPVSAMDPVLADHSLALLNRHAQAHGVTLVASLHAVELALAHFPRIIGIRAGEVAFDCPAEAVTPTMLDALYANEQLGSPVVPTATVLVQIPRC
What is the function of this protein?
Part of the ABC transporter complex PhnCDE involved in phosphonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphonates import ATP-binding protein PhnC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: VPS1_YEAST
Sequence: MDEHLISTINKLQDALAPLGGGSQSPIDLPQITVVGSQSSGKSSVLENIVGRDFLPRGTGIVTRRPLVLQLINRRPKKSEHAKVNQTANELIDLNINDDDKKKDESGKHQNEGQSEDNKEEWGEFLHLPGKKFYNFDEIRKEIVKETDKVTGANSGISSVPINLRIYSPHVLTLTLVDLPGLTKVPVGDQPPDIERQIKDMLLKYISKPNAIILSVNAANTDLANSDGLKLAREVDPEGTRTIGVLTKVDLMDQGTDVIDILAGRVIPLRYGYIPVINRGQKDIEHKKTIREALENERKFFENHPSYSSKAHYCGTPYLAKKLNSILLHHIRQTLPEIKAKIEATLKKYQNELINLGPETMDSASSVVLSMITDFSNEYAGILDGEAKELSSQELSGGARISYVFHETFKNGVDSLDPFDQIKDSDIRTIMYNSSGSAPSLFVGTEAFEVLVKQQIRRFEEPSLRLVTLVFDELVRMLKQIISQPKYSRYPALREAISNQFIQFLKDATIPTNEFVVDIIKAEQTYINTAHPDLLKGSQAMVMVEEKLHPRQVAVDPKTGKPLPTQPSSSKAPVMEEKSGFFGGFFSTKNKKKLAALESPPPVLKATGQMTERETMETEVIKLLISSYFSIVKRTIADIIPKALMLKLIVKSKTDIQKVLLEKLYGKQDIEELTKENDITIQRRKECKKMVEILRNASQIVSSV
What is the function of this protein?
Essential for protein sorting in meiotic cell division of S. cerevisiae; it binds microtubules.  Could also be involved in microtubule-associated motility.  Necessary for membrane protein retention in a late Golgi compartment.  Interacts with the MVP1 protein.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.