PharMolix/UniProtQA huggingface dataset:
Protein: REP_PCV2
Sequence: MPSKKNGRSGPQPHKRWVFTLNNPSEDERKKIREPPISLFDYFIVGEEGNEEGRTPHLQGFANFVKKQTFNKVKWYLGARCHIEKAKGTDQQNKEYCSKEGNLLIECGAPRSQGQRSDLSTAVSTLLESGSLVTVAEQHPVTFVRNFRGLAELLKVSGKMQKRDWKTNVHVIVGPPGCGKSKWAANFADPETTYWKPPRNKWWDGYHGEEVVVIDDFYGWLPWDDLLRLCDRYPLTVETKGGTVPFLARSILITSNQTPLEWYSSTAVPAVEALYRRITSLVFWKNATEQSTEEGGQFVTLSPPCPEFPYEINY
What is the function of this protein?
Essential for the replication of viral ssDNA.  The closed circular ssDNA genome is first converted to a superhelical dsDNA.  Rep and/or Rep' binds a specific hairpin at the genome origin of replication.  Introduces an endonucleolytic nick within the conserved sequence 5'-AGTATTAC-3' in the intergenic region of the genome, thereby initiating the rolling circle replication (RCR).  Following cleavage, binds covalently to the 5'-phosphate of DNA as a tyrosyl ester.  The cleavage gives rise to a free 3'-OH that serves as a primer for the cellular DNA polymerase.  The polymerase synthesizes the (+) strand DNA by rolling circle mechanism.  After one round of replication, a Rep-catalyzed nucleotidyl transfer reaction releases a circular single-stranded virus genome, thereby terminating the replication.  Displays origin-specific DNA cleavage, and nucleotidyl transferase.
What are the official names of this protein?
Replication-associated protein, ATP-dependent helicase Rep, RepP.
What is the protein family that this protein belongs to?
Belongs to the nanoviruses/circoviruses replication-associated protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: DNAJ_ORITB
Sequence: MSDLDYYQVLGVSRTASQEEIKRAYRKLVLKYHPDHNPGDKNAEQKIKNINEAYDILKDEKKRSAYDQLGHQAFKNSGGGNYQQHHGFTGGIDPNDIFENIFGDFMGARRSSKTAFSKKAGANLKYDISLTLEEAFYGVTKIISFKTALTCDACAGKGSLDNNSTSSCPTCRGSGVTRSQQGFFFFENTCQTCRGAGHVIKNPCTKCYGEGRYINTRNLEVKIPAGVKEGSRIKLTGEGEAGSRGGKTGDLYVCITLIPHNTFSVDGNDLHCQLDINCTTAALGGEVEVADITGSKLKLKIPAGTQNNHKLKLSGKGMQILHSDRCGNMIVHVNIKVPKSLTKSQRELMIKLDKELNEASEEGFLSKVRNFWASGSE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEN2_CAEEL
Sequence: MDISKLTDVKKVDLCKKYFLIGACFLPLVWIVNTFWFFSDAFCKPINAHRRQIRKYVIASIVGSIFWIIVLSAWEIFFQHYRAQGLVWTDFLTFVFPTGRV
What is the function of this protein?
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch (glp-1 or lin-12).  It may represent a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex.
What are the official names of this protein?
Gamma-secretase subunit pen-2, Presenilin enhancer protein 2.
What is the protein family that this protein belongs to?
Belongs to the PEN-2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Note=Predominantly located in the endoplasmic reticulum and Golgi region.
Protein: LDH_STRR6
Sequence: MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLHEKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNLAINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELFEGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIGQPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CMTA2_HUMAN
Sequence: MNTKDTTEVAENSHHLKIFLPKKLLECLPRCPLLPPERLRWNTNEEIASYLITFEKHDEWLSCAPKTRPQNGSIILYNRKKVKYRKDGYLWKKRKDGKTTREDHMKLKVQGMECLYGCYVHSSIVPTFHRRCYWLLQNPDIVLVHYLNVPALEDCGKGCSPIFCSISSDRREWLKWSREELLGQLKPMFHGIKWSCGNGTEEFSVEHLVQQILDTHPTKPAPRTHACLCSGGLGSGSLTHKCSSTKHRIISPKVEPRALTLTSIPHAHPPEPPPLIAPLPPELPKAHTSPSSSSSSSSSGFAEPLEIRPSPPTSRGGSSRGGTAILLLTGLEQRAGGLTPTRHLAPQADPRPSMSLAVVVGTEPSAPPAPPSPAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAAALEPQAAARGPPPQSVAGGRRGNCFFIQDDDSGEELKGHGAAPPIPSPPPSPPPSPAPLEPSSRVGRGEALFGGPVGASELEPFSLSSFPDLMGELISDEAPSIPAPTPQLSPALSTITDFSPEWSYPEGGVKVLITGPWTEAAEHYSCVFDHIAVPASLVQPGVLRCYCPAHEVGLVSLQVAGREGPLSASVLFEYRARRFLSLPSTQLDWLSLDDNQFRMSILERLEQMEKRMAEIAAAGQVPCQGPDAPPVQDEGQGPGFEARVVVLVESMIPRSTWKGPERLAHGSPFRGMSLLHLAAAQGYARLIETLSQWRSVETGSLDLEQEVDPLNVDHFSCTPLMWACALGHLEAAVLLFRWNRQALSIPDSLGRLPLSVAHSRGHVRLARCLEELQRQEPSVEPPFALSPPSSSPDTGLSSVSSPSELSDGTFSVTSAYSSAPDGSPPPAPLPASEMTMEDMAPGQLSSGVPEAPLLLMDYEATNSKGPLSSLPALPPASDDGAAPEDADSPQAVDVIPVDMISLAKQIIEATPERIKREDFVGLPEAGASMRERTGAVGLSETMSWLASYLENVDHFPSSTPPSELPFERGRLAVPSAPSWAEFLSASTSGKMESDFALLTLSDHEQRELYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQLTWIALKFALYKKMTQAAILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRSYRRRPGPPHRTSATLPARNKGSFLTKKQDQAARKIMRFLRRCRHRMRELKQNQELEGLPQPGLAT
What is the function of this protein?
Transcription activator.  May act as tumor suppressor.
What are the official names of this protein?
Calmodulin-binding transcription activator 2.
What is the protein family that this protein belongs to?
Belongs to the CAMTA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CB076_HUMAN
Sequence: MAPGEVTITVRLIRSFEHRNFKPVVYHGVNLDQTVKEFIVFLKQDIPLRTNLPPPFRNYKYDALKIIHQAHKSKTNELVLSLEDDERLLLKEDSTLKAAGIASETEIAFFCEEDYKNYKANPISSW
What are the official names of this protein?
UPF0538 protein C2orf76.
What is the protein family that this protein belongs to?
Belongs to the UPF0538 family.
Protein: GUAA_HAEIG
Sequence: MTNIHNHKILILDFGSQYTQLIARRVREIGVYCELWAWDVTEQQIREFAPTGIILSGGPESTTEENSPRAPEYVFNAGVPVLGVCYGMQTMAMQLGGLTETSDHREFGYASVSLENSTALFANLNDNSTASEPKLDVWMSHGDKVTRLPENFKVTGTTLTCPIAAMSDENRRFYGVQFHPEVTHTKKGLELLTNFVVNICGCETKWTAENIIEDAVARIKEQVGNDEVILGLSGGVDSSVVALLLHRAIGKNLHCVFVDNGLLRLHEGDQVMEMFGDKFGLNITRVDAESRFLGELAGVSDPEAKRKIIGKVFVDVFDDESKKLTNVKWLAQGTIYPDVIESAASKTGKAHVIKSHHNVGGLPDYMKLGLVEPLRELFKDEVRKIGLALGLPAEMINRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELRNSGWYEKTSQAFSVFLPVKSVGVMGDGRKYDWVISLRAVETIDFMTAHWAHLPYDLLGKVSNRIINEVNGISRVVYDISGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: PDXH_SHIB3
Sequence: MSDNDELQQIAHLRREYTKGGLRRRDLPADPLTLFERWLSQACEAKLADPTAMVVATVDEHAQPYQRIVLLKHYDEKGMVFYTNLGSRKAHQIENNPRVSLLFPWHTLERQVMVIGKAERLSTLEVMKYFHSRPRDSQIGAWVSKQSSRISARGILESKFLELKQKFQQGEVPLPSFWGGFRVSLEQIEFWQGGEHRLHDRFLYQRENDAWKIDRLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: YJ76_SCHPO
Sequence: MVNPDKTSRVYCKYTCCGYVGSLDHDKQDAHVCKLGCQLFYGESCYKEMSNALNGTSRPIFLLSVPAIEVAQLQTLGEMSLKFLIKLIVKMTDCPRQSFSCSELITVLPTVQKLTF
What are the official names of this protein?
Uncharacterized protein C757.06.
Protein: GTFB_LIMR5
Sequence: MLNLFDNFDQASFDFLRSQRTAQIKIPTVVINDDGFLPPEVESPIKYWGNYNVNKKPLYFDHLSLPRYWRILSTAAQGHIYDLDKKRADIIYQATDNTRQVKEVRWLNNNGKVSWIDHYNRYGYRFAQTYYRNEQPAWRKYYDKKNRVFLEWNLIAGDFFLDVDGGYHFPSLIELVKYYLQTRHFKLDHIFYNTLNQGLSVSLNLPADGSDTLFWHEPLSGDELPGNMKFLMENSTRTKHIIFQRYTDWQRIGANLKNNHVDFGFLGTIYPHPRANQLRPQALILTNSDEIVELSTLIKNLPNIKFHIAAVTEMSGKLLAYQQYENVELYPNVSSARVKQLIADCDIYLDINRQNEILDAVRGAFEQNMLIVGFDETLHEPQFVTPQNMFKVNEAQKMSKHIMAALLKPALMKELIDTQRQLASEVSVQDYQRMIGALQSE
What is the function of this protein?
Required for polymorphic O-glycosylation of the serine-rich repeat protein (SRRP) in this bacteria.  A stabilizing protein that is part of the accessory SecA2/SecY2 system specifically required to export serine-rich repeat cell wall proteins encoded in the same operon.  The GtfA-GtfB complex adds GlcNAc from UDP-GlcNAc to the substrate protein, attaching the first sugar residue.  Stabilizes the glycosylation activity of GtfA.  Has no N-acetylglucosaminyl transferase activity on its own.
What are the official names of this protein?
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase stabilizing protein GtfB, Glycosyltransferase stabilizing protein GtfB.
What is the protein family that this protein belongs to?
Belongs to the GtfB family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: E13C_MUSAC
Sequence: MATKASLSIKGFALLVSVLVAVPTRVQSIGVCYGMLGNNLPPPSEVVSLYKSNNIARMRLYDPNQAALQALRNSNIQVLLDVPRSDVQSLASNPSAAGDWIRRNVVAYWPSVSFRYIAVGNELIPGSDLAQYILPAMRNIYNALSSAGLQNQIKVSTAVDTGVLGTSYPPSAGAFSSAAQAYLSPIVQFLASNGAPLLVNVYPYFSYTGNPGQISLPYALFTASGVVVQDGRFSYQNLFDAIVDAVFAALERVGGANVAVVVSESGWPSAGGGAEASTSNARTYNQNLIRHVGGGTPRRPGKEIEAYIFEMFNENQKAGGIEQNFGLFYPNKQPVYQISF
What is the function of this protein?
Possesses beta-1,3-endoglucanase activity in vitro (PubMed:10672030).  May play a role in fruit pulp softening process (Probable).  Can cleave beta-1,6-branched glucans in vitro (PubMed:16421930).
What are the official names of this protein?
Glucan endo-1,3-beta-glucosidase, Beta-1,3-glucanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 17 family.
Protein: RL7A_SULAC
Sequence: MSKPSYVKFEVPQELADKVLEAVKKAKDSGKIKKGTNETTKAVERSQAKLVVIAEDVQPEEIVAHLPLLCEEKKIPYVYVPSKKSLGEACGLQVAAASVALMDPGEAKDLVDEIVKRVNEIKGKSS
What is the function of this protein?
Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
What are the official names of this protein?
50S ribosomal protein L7Ae, Ribosomal protein L8e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLOB_GLAL2
Sequence: MDLFQSPGGDLIQDEDSVEVIEMLCIDFRDRLLVALSTTCQSDFREAKKVVEERLRDILETASSLSSTEVTSSPNASPLYNTDAPEDVVPTVGLDVGLDEPMADYSQNTPSITGGTASAEYQNSGDTNQMTLEDPACVDMFAAESQNTGHIPDSCLRDWSFEGVSMKSPSLFDWSSRNSNFPLTQEHENQFAEFLTLFEGEPNFDNWLSTMTWSSLESHSSPINGHSAGATPQLDQMHTVSNSRVARSVVSESTVTNTGSANSLNSGLLANTPSSSHSSVFERACSSVQEPTPEPTPVRGLQRKLRKQGPRQTTEATPCDQQIGPRASRATSQLPERRSMKMVRKEARDTPLTTSPANSTQINIEANTIPSDLSVEYAFGCFSDAKEVFETFYKRLSDDRKHLSSLLMRLFYAVGSPDALRQLRDALDLSRKNSMIASYHDSNDLAATVSVLDQLDATTTLSHILRRYHLVRLLDHRSKLESNHKAAKLAVKGTKRRLKYDCERIELMRRGENADCDANTRSAKERLKYRSKTRALTDLMQTLYPDLSPDSEGITTAGGCEYTRKLTKLRNRLACARNWYQFEETFPGAILALIPCATGDLSISIDHVEKLPSDVLKIFLDYLKERRGVFLSKMSRILSKDLYDVLMRRNVTKRYKLEQTNENSLTDGLHDDDRLLELCETV
What is the function of this protein?
Part of the gene cluster that mediates the biosynthesis of pneumocandins, lipohexapeptides of the echinocandin family that prevent fungal cell wall formation by non-competitive inhibition of beta-1,3-glucan synthase (PubMed:27705900).  The 10,12-dimethylmyristoyl side chain is synthesized by the reducing polyketide synthase gloL/GLPKS4 (PubMed:27494047).  The thioesterase gloN/GLHYD exclusively interacts with gloL/GLPKS4 to maintain turnover of the polyketide side chain (PubMed:27494047).  The 10R,12S-dimethylmyristic acid is then transferred to the first thiolation domain of the nonribosomal peptide synthetase gloA/GLNRPS4 by the acyl-AMP ligase gloD/GLligase, followed by its acylation to L-ornithine to trigger elongation of the cyclic hexapeptide (PubMed:27494047).  L-ornithine, 4R-hydroxyl-L-proline (generated from L-proline by the dioxygenase gloF/GLOXY2), 3S-hydroxyl-L-homotyrosine (generated by gloG/GLHtyB, gloH/GLHtyA, gloI/GLHtyC, gloJ/GLHtyD and hydroxylated at C-3 by the dioxygenase gloM/GLOXY1), 3R-hydroxyl-L-glutamine (generated from L-glutamine probably by the dioxygenase gloE/GLOXY3) and 3S-hydroxyl-L-proline (generated from L-proline by the dioxygenase gloF/GLOXY2 to yield pneumocandin B0), or 3S-hydroxyl-4S-methyl-L-proline (generated from L-leucine by the dioxygenase gloC/GLOXY4 to yield pneumocandin A0) are sequentially added to the growing chain (PubMed:25270390, PubMed:25879325, PubMed:25527531).  The last C domain of gloA/GLNRPS4 is proposed to be responsible for cyclization by condensation to form the peptide bond between L-ornithine and 3S-hydroxyl-4S-methyl-L-proline (for pneumocandin A0) or 3S-hydroxyl-L-proline (for pneumocandin B0).  Finally, the subsequent C-4 hydroxylation of 3S-hydroxyl-L-homotyrosine and L-ornithine dihydroxylation at C-4 and C-5 are performed by the cytochrome P450 monooxygenases gloP/GLP450-1 and gloO/GLP450-2, respectively (PubMed:25879325).
What are the official names of this protein?
Pneumocandin biosynthesis cluster protein B.
Protein: RNFB_PSEMY
Sequence: MSLVLVAVLALLGLCLIAGAILGFAAVRFKVEGDPIAEQINALLPQTQCGQCGYPGCKPYAEAIAGGDKINKCPPGGEATIQALADLLDVEPEPLDAVEGEKPQMVAFIREAECIGCTKCIQACPVDAIVGAARQMHTVIVSECTGCDLCVEPCPVDCIDMIEVGSTVQSWKWDKPLAPGQLIASDREQAA
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit B, Rnf electron transport complex subunit B.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: RS6_PARD8
Sequence: MNNYETVFILTPVLSDAQMKEAVEKFTNLLKAQGAEIVNEENWGLRKLAYPIDKKTTGFYQLVEFKADPSVIATLELNFRRDERVIRFLTFRQDKYAAEYAAKRRNLKSSKETVKENN
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: TAL_SYNY3
Sequence: MGKNLLEQLRQFTVVVADTGDIQAIETFTPRDSTTNPSLITAAAQMPQYQEIVDSTLLKAKDEAGENASIKDIVRLAFDRLAVAFGLKILQIIPGRVSTEVDARLSYDTEATIAKARYLIGEYAKAGIDKKRILIKIASTWEGIKAAEVLEQEGIHCNLTLLFGLHQAIACAEAKVTLISPFVGRILDWYKKSTGKEYDSHEDPGVQSVTTIYNYYKRFGYKTEVMGASFRNIGEIIELAGCDLLTISPQLLDQLRNTEGDLPRKLDPATVPQDIEKIVMDKATFDKMHAEDPMASEKLAEGIAGFTKALEVLEHLLEERLKVLDGQEHIKHGAEEIFHAYDLDGDGFITREEWAGTDVVFDALDRDHDGKITAAEMSAGLGAAFRLASVG
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPEL_OCEIH
Sequence: MMLQLEQIRRDLHQIPELGFQEFKTQAYLLERINEIATENVEIKKWSTGILVYVHGKSPARKIGFRADIDGLPILEQTNLPYASLHEGRMHACGHDLHMTIALGALEKLIQDPINDDVIFVFQPAEEGPGGAKPMLESEEFQQWKPDMMFALHIAPELPVGTVSSKAGLLFANTSELFIDFEGVGGHAAYPHLTKDMTVAASNFVVQLQQIVSRGLNPLDGSVITIGKMESGYVQNAIAETARLEGTIRSTDADAIDMIKSKLNRLMKGFEISYDCTIKVDYGANYYQVVNDATYVQQFENVINQTQTITYQQADAAMTGEDFGDMLKEIPGFMFWLGVDSSYGLHNARLNPKEEAIDVGVNAVISMITSF
What is the function of this protein?
Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.
What are the official names of this protein?
N-acetyldiaminopimelate deacetylase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. N-acetyldiaminopimelate deacetylase subfamily.
Protein: URE1_STAAR
Sequence: MSFKMTQNQYTSLYGPTVGDSIRLGDTNLFAQIEKDYAVYGEEATFGGGKSIRDGMAQNPRVTRDDVNVADLVISNAVIIDYDKVVKADIGIKNGYIFAIGNAGNPDIMDNVDIIIGSTTDIIAAEGKIVTAGGIDTHVHFINPEQAEVALESGITTHIGGGTGASEGSKATTVTPGPWHIHRMLEAAEGLPINVGFTGKGQATNPTALIEQINAGAIGLKVHEDWGATPSALSHALDVADEFDVQIALHADTLNEAGFMEDTMAAVKDRVLHMYHTEGAGGGHAPDLIKSAAFPNILPSSTNPTLPYTHNTVDEHLDMVMITHHLNAAIPEDIAFADSRIRKETIAAEDVLQDMGVFSMISSDSQAMGRVGEVITRTWQVAHRMKEQRGPLDGDYVHNDNNRIKRYIAKYTINPAITHGISEYVGSIEPGKLADIVLWDPIFFGVKPELVVKGGLINSAVNGDANGSIPTSEPMKYRKMYGQYGGNLTSTSMTFVSKTAYENGINRALNLKRMVRPVKNIRQLSKADMKNNSATPKLDVDPQTYEVYVDGEKITSNAATELPLTQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_BDEBA
Sequence: MQSQKIRIRLKAFDHKLLDQSTKEIVETARRTGAKVAGPIPLPTRINRYTVLRSPHVDKKSREQFEVRTHKRMLDILEPTQQTVDQLMKLDLSAGVDVEIKLSAV
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: COXX_NOVAD
Sequence: MDSAKPLALPADWRDFFALTKPRVMTLVIFTGLCGLLAAPGTIHPVIAFTAILCIAVGAGGAAALNQWWEADIDAGMKRTAQRPLPAGRMDRTSARDFGFALAGGSVFVMGLGVGWLAAVILAFSIFYYSWIYTVWLKPRTPQNIVIGGGAGAFPPMIGWVAVTGDITLMPVLLFLIIFMWTPPHFWALALFVQTDYAKVGIPMMPVVAGERSTRKQILAYSILLLPLTLVPWWIGGAGAVYGWSALVLGLVFVALSVKVGLRRSVPNDGMLPEKRLFGYSVLYLFVLFGMLVGDRLATVQGWQ
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS12_ESCF3
Sequence: MATVNQLVRKPRARKVAKSNVPALEACPQKRGVCTRVYTTTPKKPNSALRKVCRVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGALDCSGVKDRKQARSKYGVKRPKA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: MUKB_ECOSM
Sequence: MIERGKFRSLTLINWNGFFARTFDLDELVTTLSGGNGAGKSTTMAAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGKLKAGVCYSMLDTINSRHQRVVVGVRLQQVAGRDRKVDIKPFAIQGLPMSVQPTQLVTETLSERQARVLPLNELKDKLEAMEGVQFKQFNSITDYHSLMFDLGIIARRLRSASDRSKFYRLIEASLYGGISSAITRSLRDYLLPENSGVRKAFQDMEAALRENRMTLEAIRVTQSDRDLFKHLISEATNYVAADYMRHANERRVHLDKALEFRRELHTSRQQLAAEQYKHVDMARELAEHNGAEGDLEADYQAASDHLNLVQTALRQQEKIERYEADLDELQIRLEEQNEVVAEAIERQEENEARAEAAELEVDELKSQLADYQQALDVQQTRAIQYNQAIAALNRAKELCHLPDLTADSAAEWLETFQAKELEATEKMLSLEQKMSMAQTAHSQFEQAYQLVVAINGPLARNEAWDVARELLREGVDQRHLAEQVQPLRMRLSELEQRLREQQEAERLLADFCKRQGKNFDIDELEALHQELEARIASLSDSVSNAREERMTLRQEQEQLQSRIQSLMRRAPVWLAAQNSLNQLSEQCGEEFSSSQDVTEYLQQLLEREREAIVERDEVGARKNAVDEEIERLSQPGGSEDQRLNALAERFGGVLLSEIYDDVSLEDAPYFSALYGPSRHAIVVPDLSQVTEHLEGLTDCPEDLYLIEGDPQSFDDSVFSVDELEKAVVVKIADRQWRYSRFPEVPLFGRAARESRIESLHAEREVLSERFATLSFDVQKTQRLHQAFSRFIGSHLAVAFESDPEAEIRQLNSRRVELERALSNHENDNQQQRIQFEQAKEGVTALNRILPRLNLLADDSLADRVDEIRERLDEAQEAARFVQQFGNQLAKLEPIVSVLQSDPEQFEQLKEDYAYSQQMQRDARQQAFALTEVVQRRAHFSYSDSAEMLSGNSDLNEKLRERLEQAEAERTRAREALRGHAAQLSQYNQVLASLKSSYDTKKELLNDLQRELQDIGVRADSGAEERARIRRDELHAQLSNNRSRRNQLEKALTFCEAEMDNLTRKLRKLERDYFEMREQVVTAKAGWCAVMRMVKDNGVERRLHRRELAYLSADDLRSMSDKALGALRLAVADNEHLRDVLRMSEDPKRPERKIQFFVAVYQHLRERIRQDIIRTDDPVEAIEQMEIELSRLTEELTSREQKLAISSRSVANIIRKTIQREQNRIRMLNQGLQNVSFGQVNSVRLNVNVRETHAMLLDVLSEQHEQHQDLFNSNRLTFSEALAKLYQRLNPQIDMGQRTPQTIGEELLDYRNYLEMEVEVNRGSDGWLRAESGALSTGEAIGTGMSILVMVVQSWEDESRRLRGKDISPCRLLFLDEAARLDARSIATLFELCERLQMQLIIAAPENISPEKGTTYKLVRKVFQNTEHVHVVGLRGFAPQLPETLPGSDEAPSQAS
What is the function of this protein?
Plays a central role in chromosome condensation, segregation and cell cycle progression.  Functions as a homodimer, which is essential for chromosome partition.  Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes.  May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
What are the official names of this protein?
Chromosome partition protein MukB, Structural maintenance of chromosome-related protein.
What is the protein family that this protein belongs to?
Belongs to the SMC family. MukB subfamily.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: MPG1_SULAC
Sequence: MVSAIVLAGGYATRLRPLSLTKPKALLPVLGKPLMDYTLYSLASSDVDTIYLSLRVMADKVLDHVKQLNLQKNIVSVIEESRLGDAGPLKFINSKYNLSDDVIVVYGDIYAEIDFNKLLEYHQSKGCNATLTATQVEDPSRYGVLITDGHRLIQIIEKPKTPLSNLVNAGIYVFKKELLNKIDGLSISRDFLPKLLVSDTCVSVYPYKGLWMDIGVPRDYMRINLELLTLKYPKGFISQSAKVSEKAELFPPFYIGDNTTVGEGSSIRNSIIGVNNRIGNGSCVEESILMNDVMLGDFSLIKESVIGDEVSLGKWNRVDGAIIGDGVLIHDQVFINRDTIILPDKEVAESVYDKGKIIL
What are the official names of this protein?
Putative mannose-1-phosphate guanyltransferase, ATP-mannose-1-phosphate guanylyltransferase, GDP-mannose pyrophosphorylase, NDP-hexose pyrophosphorylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: CBID_METTH
Sequence: MNDERVFGITTGTAATAAALASLLCLKGCEASKVRVRTPSGILEVDVEYVERISGDTARACVIKRPYPDPDVTVNLEIISTVQITGTPEIMIRGGEGVGIVTKPGLQVPPGEAAINPVPRRMIEENLREHLRDDEGAVVTVSVPGGERIASRTMNPRLGIIGGISILGTTGIARPMSTEAYRESLACQIDIATARGFRELVFVPGNIGERFAREYFESIEDERIIQMANFPGYMLEEADGRGVERIILMGHAGKLIKLSAGIFQTRSSDADARREIMAAHAALMGASRDTVTRIFNDGTVEEMISELEGEGLTGRVFNSIADAIRERFNERFSFDTDVLIFSLDGRILNSNFKTKRNHRFTEVF
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: DCV1_YEAST
Sequence: MLNYKLILLFSSFLQLISFSGFMICCLTSPIIRNWGLAQAAGVSYGTFGYCKTLNSFSCSRVRLIYNTSKEILPGPSLERWWLSPKARHTIGGLLISIPVATCLTFISFALPLVIIFLFQTGGTNVSLITSNAILHILTLLSTIFACTVILLLCMHRDPVTISSLYDLVWLANCSLFPLLVIGVHFLSFRFDTSAQSDRKHS
What are the official names of this protein?
Protein DCV1, Demands CDC28 kinase activity for viability protein 1.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: LIX1L_MOUSE
Sequence: METMRAQRLQPGVGVGGRGTLRALRPGVTGAPTSAATPPVGPPPAPPPPAPPLPPLLLAGAPGLPLPPGAAGSPAVLREAVEAVVRSFAKHTQGYGRVNVVEALQEFWQMKQSRGADLKNGALVVYEMVPSNSPPYVCYVTLPGGSCFGSFQFCPTKAEARRSAAKIALMNSVFNEHPSRRITDEFIEKSVSEALASFNGNREEADNPNTGIGAFRFMLESNKGKSMLEFQELMTVFQLLHWNGSLKAMRERQCSRQEVLAHYSHRALDDDIRHQMALDWVSREQSVPGALSRELASTERELDEARLAGKELRFHKEKKDILMLAAGQLGNMHSSSC
What are the official names of this protein?
LIX1-like protein.
What is the protein family that this protein belongs to?
Belongs to the LIX1 family.