PharMolix/UniProtQA huggingface dataset:
Protein: BIOB_MYCBP
Sequence: MTQAATRPTNDAGQDGGNNSDILVVARQQVLQRGEGLNQDQVLAVLQLPDDRLEELLALAHEVRMRWCGPEVEVEGIISLKTGGCPEDCHFCSQSGLFASPVRSAWLDIPSLVEAAKQTAKSGATEFCIVAAVRGPDERLMAQVAAGIEAIRNEVEINIACSLGMLTAEQVDQLAARGVHRYNHNLETARSFFANVVTTHTWEERWQTLSMVRDAGMEVCCGGILGMGETLQQRAEFAAELAELGPDEVPLNFLNPRPGTPFADLEVMPVGDALKAVAAFRLALPRTMLRFAGGREITLGDLGAKRGILGGINAVIVGNYLTTLGRPAEADLELLDELQMPLKALNASL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: RL32_PARDP
Sequence: MAVPQNRVTRSRRNMRRSHDALVAGNPNECSNCGELKRPHHVCPSCGHYADREVVAQANEVDLDEDAA
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: TRPA_STRR6
Sequence: MPKTLTEKLNAIKATGKGIFVPYIMAGDHEKGLDGLGETIHFLEDLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTYFNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGIERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQADLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: NU4M_APILI
Sequence: MYLLLLLIMLNMLMMSMIYLFMLFMNKMKNNLNLIIGNLIIINLLLNLFNLNWIDWIYIFCNLSFNMYSYGLIMLTLWIFGLIFISLNNNSLNCLFMNLLLMISLLLVFLSMNLLLFYLFYEFGLLLIFYLVVKWGYSENRWLSGFYLMFYTMIFSLPMLYIIYYIYLIDYSLNFMLMEMLNLNLNMMLFIYLLMSFLVKIPIYLFHGWLLKAHVEAPYYGSMILASIMLKLGGYGMLRLMIIYKNEFILIQKILVMINSFGVLILSLMCLSQFDMKSIIAISSIVHMGLMIMSMMTFLKISLIGGYLMMISHGLSSSGLFFLVNVIYSQTNSRLMFINKGMINFMPSMSLLWFMLCSSNMGSPVSLNLISEVMLLIGMISWLKFMMLILMMYCLFSFIYSIYLFMFINHGKIFIMFKIKNGILVEYFVLLLHWIPLNLMFLKLYFI
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: RLMF_ECOLI
Sequence: MSAQKPGLHPRNRHHSRYDLATLCQVNPELRQFLTLTPAGEQSVDFANPLAVKALNKALLAHFYAVANWDIPDGFLCPPVPGRADYIHHLADLLAEASGTIPANASILDIGVGANCIYPLIGVHEYGWRFTGSETSSQALSSAQAIISSNPGLNRAIRLRRQKESGAIFNGIIHKNEQYDATLCNPPFHDSAAAARAGSERKRRNLGLNKDDALNFGGQQQELWCEGGEVTFIKKMIEESKGFAKQVMWFTSLVSRGENLPPLYRALTDVGAVKVVKKEMAQGQKQSRFIAWTFMNDEQRRRFVNRQR
What is the function of this protein?
Specifically methylates the adenine in position 1618 of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase F, 23S rRNA mA1618 methyltransferase, rRNA adenine N-6-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL16/RlmF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOCD_KLEP3
Sequence: MVNNMTDLTAHDAAPAWQTRDHLDDPVIGELRNRFGPDAFTVQPTRTGVPVVWVKREQLLEVGDFLKKLPKPYVMLFDLHGMDERLRTHRDGLPAADFSVFYHLISIDRNRDIMLKVALSENDLHLPTFTKLFPNANWYERETWEMFGMTFDGHPNLRRIMMPPTWEGHPLRKDYPARATEFDPFELTKAKQDLEMEALTFKPEEWGMKRSTDNEDFMFLNLGPNHPSAHGAFRIILQLDGEEIVDCVPDIGYHHRGAEKMGERQSWHSYIPYTDRIEYLGGCVNEMPYVLAVEKLAGITVPDRVNVIRVMLSELFRINSHLLYISTFIQDVGAMTPVFFAFTDRQKIYDLVEAITGFRMHPAWFRIGGVAHDLPRGWDRLLREFLEWMPKRLDSYEKAALRNTILKGRSVGVAAYTAKEALEWGTTGAGLRATGIGFDVRKWRPYSGYENFDFEVPTGGGVSDCYTRVMLKVEELRQSLRILQQCLDNMPEGPFKADHPLTTPPPKERTLQHIETLITHFLQVSWGPVMPANESFQMIEATKGINSYYLTSDGSTMSYRTRVRTPSFAHLQQIPSAIRGSLVSDLIVYLGSIDFVMSDVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RK16_IPOPU
Sequence: MLSPKRTRFRKQHRGRMKGISSGGNHICFGKYALQALEPAWITSRQIEAGRRAMTRNARRGGKIWVRIFPDKPVTVRPAETRMGSGKGSPEYWVAVVKPGRILYEMGGVTKKIARRAISIAASKMPIRTQFISSEIEEKSKTTRKES
What are the official names of this protein?
50S ribosomal protein L16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y1539_METJA
Sequence: MGIDMSEEKEVKEIKVEIPKEIADKIEKITSFLNSLKDKKEMVSKEKIEEMLKLIDEVKDKLPKLNVDIEKLAKILEGSGSEVKIVFNKLTIDGEVGLKIIPLKKEKKE
What are the official names of this protein?
Uncharacterized protein MJ1539.
What is the protein family that this protein belongs to?
To A.fulgidus AF1885.
Protein: RL33_PARMW
Sequence: MAKNKGVRIVITLECTECRSNPAKRSPGVSRYTTEKNRRNTTERLEIKKFCPHCNKMTPHKEIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: Y685_METJA
Sequence: MIIAVSGKGGVGKTAFTTLLIKALSKKTNSILVVDADPDSNLPETLGVEVEKTVGDIREELKKLVERDEIPAGMTKLDYLRSKIFEILVETKYYDLLVMGRPEGSGCYCSVNNWLRQIIDNLAKDYEFVVIDTEAGLEHLSRRTTQNVDVMIVITDASKRGLGTAKRIKKLANELEVKFKDIYVVANKVKPEYEELIDNYAKELGLNLIGKLPYNKEIAEYDLKGIPLWNLPENNEVYKKVEEIAEKIINKKF
What are the official names of this protein?
Uncharacterized ATP-binding protein MJ0685.
What is the protein family that this protein belongs to?
To M.jannaschii MJ0084 and MJ0823.
Protein: MEP10_UNCRE
Sequence: MHGLLLAATLLSLPFNAVAHVPPTTGLVRRGVDLDSFRLNERSQFKISEQVEKDSGVSALHSRNYVDVATRLVKRVAPKATFRLVDDHYIGDTGVGHVYFRQTINGVDVDNGDFNVNIGRNGRVFSYGNSFHTGDVPESNLRVKEDPSNPVQALHGALKALRIPIKAERAVAEATNEEDDEDFVLKGTSGALADPTAKLVYLMKNDGSLALTWRVETDIGDNWLLTYVDAEDTTKVHNVVDYVAHATYKVYRWGIADPTEGELEVISDPWNLRTSEFTWHGNGTTRFSTTIGNNGIAQSNPTGGSEYLNNYRPQPADLKFEYDYSPSMNPPSTYIDASITQLWYSANTYHDLLYMLGFNERSGNFETNNNNQGGKGNDYVILNAQDGSGTNNANFATPPDGRPGRMRMYIWTRANPPRDVCFEEGTVVHEYTHGLSNRLTGGPANSRCLNALESGGMGEGWSDFFATAVRLKPKDTRHTDYPKGAWVANNPRGVRQYVYSTNMTTNPLVYTTVNSLNQVHAIGTVWATILYEVLWNLIDKHGKNDGPTPKFRNGVPTDGKYLAMKLVLDGLALQPCNPNFVQARDAILDADKILTGGRNQCELWKGFAKRELGTGAKWDPRNRVGSTRVPVICRIFT
What is the function of this protein?
Secreted metalloproteinase that allows assimilation of proteinaceous substrates.
What are the official names of this protein?
Extracellular metalloproteinase 10, Elastinolytic metalloproteinase MEP10, Fungalysin MEP10.
What is the protein family that this protein belongs to?
Belongs to the peptidase M36 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS17_LISMO
Sequence: MADRNQRKVYTGRVVSDKMDKTITVVVETYKKHGLYGKRVKYSKKFKAHDENNIAKTGDVVRISETRPLSATKHFRLLEVVEEAVII
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: URED2_BRUA4
Sequence: MSTGWHAELELRFEHNREVTRLMRRRHVGPLAVQQPFYPEKDGSAHVYLLHPPGGVAGDDVLDISCFLGRGARAVLTTPGATKFYRSERGQSTQTTRIDVGEGGICEYLPQETIVFDGAKASIGTKVFLSGDAVYLGWDIISLGRPACQESFDTGEVRQRIEIFRDGKPIWFEQFRLHGADPALNAAFAFCAKPIVATMVYAGPADESALHAIREAVGDAARNLFSVSRLERVIVCRYLGGRMSEAKTLFRKAWEVLRETGLGKPAAAPRIWAT
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD 2.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISK2_MOUSE
Sequence: MLRLVLLLLVTDFAASHETLDSSDSQIMKRSQFRTPDCGHFDFPACPRNLNPVCGTDMNTYSNECTLCMKIREDGSHINIIKDEPC
What is the function of this protein?
As a strong inhibitor of acrosin, it is required for normal spermiogenesis.  It probably hinders premature activation of proacrosin and other proteases, thus preventing the cascade of events leading to spermiogenesis defects (PubMed:21705336, PubMed:28554943).  May be involved in the regulation of serine protease-dependent germ cell apoptosis (PubMed:21705336).  It also inhibits trypsin (PubMed:21705336).
What are the official names of this protein?
Serine protease inhibitor Kazal-type 2.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic vesicle, secretory vesicle, acrosome.
Protein: NU1M_DROME
Sequence: MEFILSLIGSLLLIICVLVSVAFLTLLERKVLGYIQIRKGPNKVGLMGIPQPFCDAIKLFTKEQTYPLLSNYLSYYISPIFSLFLSLFVWMCMPFFVKLYSFNLGGLFFLCCTSLGVYTVMVAGWSSNSNYALLGGLRAVAQTISYEVSLALILLSFIFLIGSYNMIYFFFYQVYMWFLIILFPMALVWMSISLAETNRTPFDFAEGESELVSGFNVEYSSGGFALIFMAEYASILFMSMLFCVIFLGCDVFNLLFYMKLTFISFVFIWVRGTLPRFRYDKLMYLAWKCFLSFSLNYLLFFIGFKILLFSLL
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GLPE_HAEIE
Sequence: MSFKEITPQQAWEMMQQGAILVDIRDNMRFAYSHPKGAFHLTNQSFLQFEELADFDSPIIVSCYHGVSSRNVATFLVEQGYENVFSMIGGFDGWCRAELPIDTAY
What is the function of this protein?
Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
What are the official names of this protein?
Thiosulfate sulfurtransferase GlpE.
What is the protein family that this protein belongs to?
Belongs to the GlpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNG_PSESM
Sequence: MTSDDRIKLEPSWKEALRDEFEQPYMAQLREFLRQEHAAGKEIYPPGPLIFNALNSTPLDNVKVVILGQDPYHGPNQAHGLCFSVQPGVPTPPSLVNIYKELKRDLNIDIPNHGCLQSWADQGVLMLNTTLTVERANAASHAGKGWQHFTDRIIQVVSEHQPHLVFLLWGAHAQGKQKLVDATKHLVLTSVHPSPLSAYKGFLGNGHFGRANKYLEQNGLAPIDWRLPAL
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS5_PYRAB
Sequence: MSQEWKEYAKRVLDEWQPKTKLGMLVKEGQITDIHEIFRKGYQIKEPEIIDVLLPEVNARENQEILDIALTVRMTDSGRRVRFRVLAAVGNRDGYVGLGIGHGREVGIAIRKAINYAKLNIIEIKRGCGSWECRCRRPHSVPFTVEGKEGSVRVKLIPGPRGLGLVIGDVGKKILRLAGIQDVWSQTLGETRTTVNFAKAVFNALYNTNKVVVTPEMIERYGIVVGRAMPASFTLE
What is the function of this protein?
With S4 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: SKI11_ARATH
Sequence: MLEDRSPDSCLSTRVFSSSRLSESNWSNSYMYPEDDDKLLGNGKRALEVVGEVRQTKSLKLMGFSIIYDSDSSDYSLSGGEEQADAAIGDGSSSRQEQEQQSDFNDNGGDSSDSHSLINEIGRDNSIDCLIRCSRSDYGSIASLNRNFRSLVKSGEIYRLRRQNGFVEHWVYFSCQLLEWVAFDPVERRWMQLPTMPSSVTFMCADKESLAVGTDLLVLGKDDFSSHVIYRYSLLTNSWSSGMKMNSPRCLFGSASLGEIAIFAGGCDSQGKILDFAEMYNSELQTWITLPRMNKPRKMCSGVFMDGKFYVIGGIGGADSKGLTCGEEYDLETKKWTQIPDLSPPRSRADQADMSPAAEAPPLVAVVNNQLYAADHADMEVRKYDKENKKWLTVGRLPERAGSVNGWGLAFRACGERLIVIGGPKCSGGGFIELNSWIPSDGGPPQWTLLDRKHSPTFVYNCAVMGC
What is the function of this protein?
Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
F-box/kelch-repeat protein SKIP11, SKP1-interacting partner 11.
What are the subcellular locations of this protein?
Nucleus.
Protein: IOLI_BACSU
Sequence: MKLCFNEATTLENSNLKLDLELCEKHGYDYIEIRTMDKLPEYLKDHSLDDLAEYFQTHHIKPLALNALVFFNNRDEKGHNEIITEFKGMMETCKTLGVKYVVAVPLVTEQKIVKEEIKKSSVDVLTELSDIAEPYGVKIALEFVGHPQCTVNTFEQAYEIVNTVNRDNVGLVLDSFHFHAMGSNIESLKQADGKKIFIYHIDDTEDFPIGFLTDEDRVWPGQGAIDLDAHLSALKEIGFSDVVSVELFRPEYYKLTAEEAIQTAKKTTVDVVSKYFSM
What is the function of this protein?
Involved in the reversible interconverion of 2-keto-myo-inositol (2KMI, inosose or 2,4,6/3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5/4,6-pentahydroxycyclohexanone).
What are the official names of this protein?
Inosose isomerase, 2-keto-myo-inositol isomerase, 2KMI isomerase.
What is the protein family that this protein belongs to?
Belongs to the IolI family.
Protein: POLC3_CHEAL
Sequence: MAAEDTPQDIADRERIFKRFDTNGDGKISSSELGDALKTLGSVTPDEVRRMMAEIDTDGDGFISFDEFTDFARANRGLVKDVSKIF
What are the official names of this protein?
Polcalcin Che a 3, Calcium-binding pollen allergen Che a 3.
Protein: HLDE_ECO45
Sequence: MKVTLPEFERAGVMVVGDVMLDRYWYGPTSRISPEAPVPVVKVNTIEERPGGAANVAMNIASLGANARLVGLTGIDDAARALSKSLADVNVKCDFVSVPTHPTITKLRVLSRNQQLIRLDFEEGFEGVDPQPLHERINQALSSIGALVLSDYAKGALASVQQMIQLARKAGVPVLIDPKGTDFERYRGATLLTPNLSEFEAVVGKCKTEEEIVERGMKLIADYELSALLVTRSEQGMSLLQPGKAPLHMPTQAQEVYDVTGAGDTVIGVLAATLAAGNSLEEACFFANAAAGVVVGKLGTSTVSPIELENAVRGRADTGFGVMTEEELKLAVAAARKRGEKVVMTNGVFDILHAGHVSYLANARKLGDRLIVAVNSDASTKRLKGDSRPVNPLEQRMIVLGALEAVDWVVSFEEDTPQRLIAGILPDLLVKGGDYKPEEIAGSKEVWANGGEVLVLNFEDGCSTTNIIKKIQLDKKG
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: RND_BARHE
Sequence: MRTKTQKKSQEKTNLNLSGYNRMMKLITQTTDLEIALATLRNSDFVTIDTEFIRETTFWPQLCLIQLASPDTTVLIDPISQDIDLKPFFDLMVNKKIVKVFHAARQDIETIYHLGGVIPSPLFDTQIAGSICGFGDSISYDQIVQRCTGYQLDKSSRFTDWSFRPLSEKQLLYALADVTYLRDVYLLLKKQLEKNKRTHWMDDEIAVLLEPKTYDMPENEAWKKVKGKIKKPRELAVLQKIAAWRERKARQYNIPRRHIIKDECLIEIAIQQPKDEADLKRLRSLNKNWDKFSIAHTLIKAVHEGLEVDLATLPALPKHNPLNETSSAVIDLLKVLLKLVANENGIAPKIIATSNDLEKIANGCIKKNIPAMNGWRYEIFGQKAEQMLKGKIGFYLSNGKINTKQL
What is the function of this protein?
Exonuclease involved in the 3' processing of various precursor tRNAs.  Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.
What are the official names of this protein?
Ribonuclease D, RNase D.
What is the protein family that this protein belongs to?
Belongs to the RNase D family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MMGT2_RAT
Sequence: MVAWLWKVLVGVGLSALAHAAFSAAQHRSHTRLAEMKYEPLPTDIVLQTLLAFALTCYGVVHTAGDFRDRDATSELKNVTFDTLRNRPSFYVFQHSGSSLLQPSDTTRSSNLNVPSSDDIRLKF
What is the function of this protein?
Mediates Mg(2+) transport.
What are the official names of this protein?
Membrane magnesium transporter 2.
What is the protein family that this protein belongs to?
Belongs to the membrane magnesium transporter (TC 1.A.67) family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein.
Protein: MNMA_BRUA1
Sequence: MSLNSLDLPGKPEDTRVVVAMSGGVDSSVVAGILKREGYDVVGVTLQLYDHGAAVHRAGSCCAGQDIEDARRVSESLGIPHYVLDYEARFREAVIDPFANSYVSGETPIPCVSCNQTVKFADLLQTARDLGADALATGHYIRSRANGAHRALYRPVDTDRDQSYFLFATTQEQIDYLRFPLGHLPKAQVREIAEELGLTVAKKQDSQDICFVPQGKYSDIISRLKPEAANPGDIVHIDGRTLGRHDGIVHYTVGQRRGIGVATGEALYVVHLDAANARVIVGPREALETHKVFLRDVNWLGDTPIADLPKSGMEVFAKVRSTRPPRPAVLRHADGQTWVELVDGESGIAPGQACVLYSDDSNAARVFGGGFIGRSEREPQAEEMLRRLMANADKASAA
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EDC4_HUMAN
Sequence: MASCASIDIEDATQHLRDILKLDRPAGGPSAESPRPSSAYNGDLNGLLVPDPLCSGDSTSANKTGLRTMPPINLQEKQVICLSGDDSSTCIGILAKEVEIVASSDSSISSKARGSNKVKIQPVAKYDWEQKYYYGNLIAVSNSFLAYAIRAANNGSAMVRVISVSTSERTLLKGFTGSVADLAFAHLNSPQLACLDEAGNLFVWRLALVNGKIQEEILVHIRQPEGTPLNHFRRIIWCPFIPEESEDCCEESSPTVALLHEDRAEVWDLDMLRSSHSTWPVDVSQIKQGFIVVKGHSTCLSEGALSPDGTVLATASHDGYVKFWQIYIEGQDEPRCLHEWKPHDGRPLSCLLFCDNHKKQDPDVPFWRFLITGADQNRELKMWCTVSWTCLQTIRFSPDIFSSVSVPPSLKVCLDLSAEYLILSDVQRKVLYVMELLQNQEEGHACFSSISEFLLTHPVLSFGIQVVSRCRLRHTEVLPAEEENDSLGADGTHGAGAMESAAGVLIKLFCVHTKALQDVQIRFQPQLNPDVVAPLPTHTAHEDFTFGESRPELGSEGLGSAAHGSQPDLRRIVELPAPADFLSLSSETKPKLMTPDAFMTPSASLQQITASPSSSSSGSSSSSSSSSSSLTAVSAMSSTSAVDPSLTRPPEELTLSPKLQLDGSLTMSSSGSLQASPRGLLPGLLPAPADKLTPKGPGQVPTATSALSLELQEVEPLGLPQASPSRTRSPDVISSASTALSQDIPEIASEALSRGFGSSAPEGLEPDSMASAASALHLLSPRPRPGPELGPQLGLDGGPGDGDRHNTPSLLEAALTQEASTPDSQVWPTAPDITRETCSTLAESPRNGLQEKHKSLAFHRPPYHLLQQRDSQDASAEQSDHDDEVASLASASGGFGTKVPAPRLPAKDWKTKGSPRTSPKLKRKSKKDDGDAAMGSRLTEHQVAEPPEDWPALIWQQQRELAELRHSQEELLQRLCTQLEGLQSTVTGHVERALETRHEQEQRRLERALAEGQQRGGQLQEQLTQQLSQALSSAVAGRLERSIRDEIKKTVPPCVSRSLEPMAGQLSNSVATKLTAVEGSMKENISKLLKSKNLTDAIARAAADTLQGPMQAAYREAFQSVVLPAFEKSCQAMFQQINDSFRLGTQEYLQQLESHMKSRKAREQEAREPVLAQLRGLVSTLQSATEQMAATVAGSVRAEVQHQLHVAVGSLQESILAQVQRIVKGEVSVALKEQQAAVTSSIMQAMRSAAGTPVPSAHLDCQAQQAHILQLLQQGHLNQAFQQALTAADLNLVLYVCETVDPAQVFGQPPCPLSQPVLLSLIQQLASDLGTRTDLKLSYLEEAVMHLDHSDPITRDHMGSVMAQVRQKLFQFLQAEPHNSLGKAARRLSLMLHGLVTPSLP
What is the function of this protein?
In the process of mRNA degradation, seems to play a role in mRNA decapping.  Component of a complex containing DCP2 and DCP1A which functions in decapping of ARE-containing mRNAs.  Promotes complex formation between DCP1A and DCP2.  Enhances the catalytic activity of DCP2 (in vitro).
What are the official names of this protein?
Enhancer of mRNA-decapping protein 4, Autoantigen Ge-1, Autoantigen RCD-8, Human enhancer of decapping large subunit, Hedls.
What is the protein family that this protein belongs to?
Belongs to the WD repeat EDC4 family.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Nucleus.
Protein: PESC_DROVI
Sequence: MRRPKKYEAGEATQYISRRAALRKLQLSLNDFRRLCILKGVYPREPKHRRRAQKGSSDIKILYHAKDIRFLLHEPIVWTLRDYKIFAKKSGRDRAIKDFRNLKRRLAMFPEIKLDHIVKERYPTFIDALKDLDDCLTLLFLFSTFPSLHLIPREQSNLCRRLTIEFLHYVIASKSLRKVFISIKGYYFQAEIKGQKVTWIVPHYYPFKPQSRQEVDFKVMSIFVEFYTIMLGFTNFRLYHGLNLAYPPQFPSNMLQDNADTLKDESSFVSDRITALNFELLRTDKVQEDEEEPDIDMELLEQDGDSKRIIKMKQEAQEVSRLRTLFKGLKFFINREVPREPLVIIIRSFGGKVSWDSSVFSGATYDESDETITHQIVDRPSLSTQYISRDYIQPQWIFDCVNQRQLLPTNKYFLGEPLPPHLSPFVDAKRDTYIPPEEKALHDPSLIETHAQSEDESEDDAAAEEEDTVEQELLDAQLQRAYQQETAEYKKYGGADGVNEDEEDSDEEDFDGEEQESDDDDEEELDEKEKRLLEEKQKMSVQSGKVHKVNKRQVHKAEVDEHRLQARMVKPRHRNLFRKLIREKQAKEKEEWLLRKKRRTIETDAKEAKKLAKREARKAAAAAAAAAAQLGAK
What is the function of this protein?
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
What are the official names of this protein?
Pescadillo homolog.
What is the protein family that this protein belongs to?
Belongs to the pescadillo family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: PDIA5_BOVIN
Sequence: MARVVPAWLLLPLAVWVVLPTWLSSAKFSSLIERISDPKDLKKLLRTRNNVLVLYSKSEAAAESHLKLLSTVAQAVKGQGTICWVDCGDAESRKLCKKMKVDLSAKDKKVELFHYQDGAFHTEYNRAVTFKSIVAFLKDPKGPPLWEEDPGAKDVVHIDNEKDFRRLLKKEEKPILMMFYAPWCSVCKRIMPHFQKAATQLRGQFVLAGMNVYPSEFENIKEEYSVRGYPTICYFEKGRFLFQYDSYGSTAEDIVEWLKNPQPPQPQVPETPWADEGGSVYHLSDEDFDQFVKEHSSVLVMFHAPWCGHCKKMKPEFESAAEVLHGEGDSSGVLAAVDATVNKALAERFHIAEFPTLKYFKNGEKYAVPALRTKKSFIEWMRNPESPPPPDPAWEEQQTSVLHLSGDNFRETLKRKKHALVMFYAPWCPHCKKAIPHFTAAADAFKDDRKIACAAIDCVKENNKDLCQQEAVKAYPTFHYYHYGKFVEKYDTNPTELGFTSFIRTLREGDHERLGKKKEEL
What are the official names of this protein?
Protein disulfide-isomerase A5.
What is the protein family that this protein belongs to?
Belongs to the protein disulfide isomerase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: LGOT_ECOLI
Sequence: MEKENITIDPRSSFTPSSSADIPVPPDGLVQRSTRIKRIQTTAMLLLFFAAVINYLDRSSLSVANLTIREELGLSATEIGALLSVFSLAYGIAQLPCGPLLDRKGPRLMLGLGMFFWSLFQAMSGMVHNFTQFVLVRIGMGIGEAPMNPCGVKVINDWFNIKERGRPMGFFNAASTIGVAVSPPILAAMMLVMGWRGMFITIGVLGIFLAIGWYMLYRNREHVELTAVEQAYLNAGSVNARRDPLSFAEWRSLFRNRTMWGMMLGFSGINYTAWLYLAWLPGYLQTAYNLDLKSTGLMAAIPFLFGAAGMLVNGYVTDWLVKGGMAPIKSRKICIIAGMFCSAAFTLIVPQATTSMTAVLLIGMALFCIHFAGTSCWGLIHVAVASRMTASVGSIQNFASFICASFAPIITGFIVDTTHSFRLALIICGCVTAAGALAYIFLVRQPINDPRKD
What is the function of this protein?
Probably responsible for the transport of L-galactonate from the periplasm across the inner membrane.  Is essential for growth on L-galactonate as the sole carbon source.
What are the official names of this protein?
Probable L-galactonate transporter, Galactonate:H(+) symporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Phthalate permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CEN_ARATH
Sequence: MARISSDPLMVGRVIGDVVDNCLQAVKMTVTYNSDKQVYNGHELFPSVVTYKPKVEVHGGDMRSFFTLVMTDPDVPGPSDPYLREHLHWIVTDIPGTTDVSFGKEIIGYEMPRPNIGIHRFVYLLFKQTRRGSVVSVPSYRDQFNTREFAHENDLGLPVAAVFFNCQRETAARRR
What is the function of this protein?
May form complexes with phosphorylated ligands by interfering with kinases and their effectors (By similarity).  Can substitute for TERMINAL FLOWER 1 (in vitro).
What are the official names of this protein?
Protein CENTRORADIALIS-like.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylethanolamine-binding protein family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOB_LATSS
Sequence: MQFKRVFTVVLDSVGIGEASDAANFNDVGADTLGHIGAFYGEQFKLPNLQKLGLGNIRASDPIKGVPAAQPALGYFGKMQETSVGKDSMDGHWEMMGLPVKEPLGFFPNGFPNELIQKLAAFSGRSVIVNRPYSGTDVIRDYGEEQLATGALIVYTSGDSVLQIAANEAVIPLEELYRICEYARQITIEKPYRIGRVIARPFKGQDKDHFERTSDRHDYTLEPTGTTDMDRLKAAGLDVLAVGKINDIFSGKGITSGVHTESNHDGMVQTIKNAQTDFTGFSFTNLVDFDAMYGHRRNPEGYGAALMAFDQQLGELLAVLKPDDLLLITADHGNDPGFRGTDHTREYVPLLAYSSRLSGNQSLGVRSTFADLGATILENFDCPAGEVGTSFLTQLK
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.