PharMolix/UniProtQA huggingface dataset:
Protein: TIG_METEP
Sequence: MQVTETTSEGLKREFQVLLPANELEDRLNTELSNIKGKVQIKGFRPGKVPVAHLRKVYGKSVMADVLQNAVNEANQQIVTDKGLRLALEPQIEFPKDEEQTIIERALDAKGDLAFKVKLEVLPSFELADLSDVSIKKLVLKPSDEEVNETLERMAKDSRSFEPREEGAEAQSGDRVTIDFVGRIDGTEFEGGKGEDVDLELGSNTFIPGFEDQLVGAKVGDSRLVKVAFPADYQAEQLAGKDAEFDVTVKAVAAPGETKIDDELAKRFGMDDLEKLKEAVSKAVGSDYEAQSRRKLKKELLDALDGKYAFDLPPSLVHQEFAAVWAQVEQDLKTRGKTFEDEGTTEEASQAEYRKIAERRVRLGLVLAQVGETADIKVSDDEVNQALFARIRQFPGQEKQVYDFYRNNPQALAELRAPLFEEKVVDHVLGQVQVVEEPVSKEALFAEDDEADAVTGGAATDEKPSESNNEAAADKAAG
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: MOB1B_HUMAN
Sequence: MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
What is the function of this protein?
Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.  The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ.  Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration.  Stimulates the kinase activity of STK38L.
What are the official names of this protein?
MOB kinase activator 1B, Mob1 homolog 1A, Mob1A, Mob1B, Mps one binder kinase activator-like 1A.
What is the protein family that this protein belongs to?
Belongs to the MOB1/phocein family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: VMA21_SCHPO
Sequence: MERKSQVSDTNNNSIPTNVLLKFVGFSVALFTLPLITYFWTLKTLFKGYQTLYAGLSAAVMVNIILALYIVAAFREDSGTPKKDIKRE
What is the function of this protein?
Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.
What are the official names of this protein?
Vacuolar ATPase assembly integral membrane protein vma21.
What is the protein family that this protein belongs to?
Belongs to the VMA21 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein.
Protein: NTPPB_PSESM
Sequence: MPSLLLASSSPYRRELLARLRLPFACESPDIDESHRPGETPHDLVQRLAREKAEALASEYPGHLIIGSDQVAVLDGQILGKPHTFERAREQLTAASDTRVTFLTGLALLNSSTGECQVDCVPFTVHMRELDQASIERYLRAETPYDCAGSFKAEGLGVSLFRSTQGADATSLIGLPLIRLVDMLIKEGVSVP
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP).  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
7-methyl-GTP pyrophosphatase, m(7)GTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YceF subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACAC_CHICK
Sequence: MEESSQPAKPLEMNPHSRFIIGSVSEDNSEDETSSLVKLDLLEEKERSLSPVSVCSDSLSDLGLPSAQDGLANHMRPSMSGLHLVKQGRDRKKVDVQRDFTVASPAEFVTRFGGNRVIEKVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLHKNGIAFMGPPSQAMWALGDKIASSIVAQTAGIPTLPWNGSGLRVDWQENDLQKRILNVPQELYEKGYVKDADDGLRAAEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPASIATSVVFEHMEQCAVKLAKMVGYVSAGTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLHRIKDIRVMYGVSPWGDGSIDFENSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLETESFQQNRIDTGWLDRLIAEKVQAERPDTMLGVVCGALHVADVSFRNSVSNFLHSLERGQVLPAHTLLNTVDVELIYEGRKYVLKVTRQSPNSYVVIMNSSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRYRITIGNKTCVFEKENDPSILRSPSAGKLIQYVVEDGGHVFAGQCFAEIEVMKMVMTLTAGESGCIHYVKRPGAVLDPGCVIAKLQLDDPSRVQQAELHTGTLPQIQSTALRGEKLHRIFHYVLDNLVNVMNGYCLPEPYFSSKVKGWVERLMKTLRDPSLPLLELQDIMTSVSGRIPPNVEKSIKKEMAQYASNITSVLCQFPSQQIANILDSHAATLNRKSEREVFFMNTQSIVQLVQRYRSGIRGHMKAVVMDLLRQYLKVETQFQHGHYDKCVFALREENKSDMNAVLNYIFSHAQVTKKNLLVTMLIDQLCGRDPTLTDELINILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNRMSFSSNLNHYGMVHVASVSDVLLDNSFTPPCQRMGGMVSFRTFEDFVRIFDEVMSCFCDSPPQSPTFPEAGHASLYDEDKAAREEPIHILNVAIKTDGDVDDDGLAAMFREFTQSKKSVLIEHGIRRLTFLVAQKREFPKFFTFRARDKFEEDRIYRHLEPALAFQLELNRMRNFDLTAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEYLQNEGERLLLEAMDELEVAFNNTNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAELKINIRLTPTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTGQIMFQAYGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGTSYVYDIPEMFRQSLIKLWDSMNEHAFLPTPPLPSDILTYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMTLKTPEYPEGRDIIVIGNDITYRIGSFGPQEDVLFLRASELARTHGIPRIYVAANSGARIGLAEEIRHMFHVAWEDPDDPYKGYKYLYLTPQDYKKVSALNSVHCEHVEDNGESRYKITDIIGKEDGLGIENLRGSGMIAGESSLAYESIITINLVTCRAIGIGAYLVRLGQRTIQVENSHIILTGCGALNKVLGREVYTSNNQLGGIQIMHNNGVTHGTVCDDFEGVYTILLWLSYMPKSVYSPVPILKVKDPIDRTIDFVPTKTPYDPRWMLAGRPNPSQKGQWQSGFFDNGSFLEIMQPWAQTVVVGRARLGGIPVGVVAVETRTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTAQAINDFNREGLPLMVFANWRGFSGGMKDMYDQVLKFGAYIVDGLREYRQPVLIYIPPQAELRGGSWAVIDPTINPRHMEMYADRESRGGILEPEGTVEIKFRRKDLVKTMRRVDPVYMRLAERLGTPELSAADRKDLESKLKEREEFLIPIYHQVAMQFADLHDTPGRMQEKGAITDILDWKTSRTFFYWRLRRLLLEDVVKKKIHDANPELTDGQIQAMLRRWFVEVEGTVKAYLWDSNKDLVEWLEKQLMEEEGVRSVVDENIKYISRDYILKQIRSLVQANPEVAMDSIVHMTQHISPTQRAEIVRILSTMDSPSST
What is the function of this protein?
Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids.  Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.
What are the official names of this protein?
Acetyl-CoA carboxylase, ACC.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COC1C_CONCL
Sequence: DVCDSLVEGRCIHNGCWCDEEAPHGNCCDTAGCTAWWWCPGTKFD
What is the function of this protein?
Mu-conotoxins block voltage-gated sodium channels.  This toxin reversibly blocks voltage-gated sodium channel in cephalopods, with no alteration in the voltage dependence of sodium conductance or on the kinetics of inactivation (By similarity).
What are the official names of this protein?
Mu-conotoxin-like Cal 12.1.1c, Conotoxin CalTx 12.1.1D.
What are the subcellular locations of this protein?
Secreted.
Protein: PCF7_ORYSI
Sequence: MSGFTNKDGRQNLAPCFNFRSSPFRLTVGERELKLEEDKNQLSKGLDPWTSNPTASASTLHYLLQEKERAQQAHEQLQIYQQQQGFGSFLQHRIRQPASRGPGGGGGGGDGGGSSGESTPVDALATAFGAGRIVRSAAGRKDRHSKVCTARGLRDRRVRLAAHTAIRFYDVQDRLGYDRPSKAVDWLMRNAKAAIDELPDRAEAPPPPAAASTEQPEGTEQANSTSYGFGNTTGGTMTSAASAAAGSFLPHSLGADRVSDSVKSLFPSSSTASGAASAGHDEYRGSPPDLLSRTTSNQQPQELCLTLQSNQHQIFSHVSSNHHGMISSAGVPGWPDHSQRMQAWHAPENSTGDGRGGGNGDGYMFAMPSRQGLDQSQLFSHGEPLQSSGRGWASARAWLDPLAVAAIHHQPSTMAAGQVGFGHLVGGAGGGGGFMGFLAPAAQRLEGEEEHGSEVIR
What is the function of this protein?
Transcription activator.  Binds the promoter core sequence 5'-GGNCC-3'.
What are the official names of this protein?
Transcription factor PCF7.
What are the subcellular locations of this protein?
Nucleus.
Protein: HUTG_SALNS
Sequence: MTQWYPASPALWQGRDDSIEAPDARRLFQTVTRSETFSPENWQQKIALMGFACDEGVKRNAGRPGAAGGPDALRKALANMASHQGHERLVDLGNWVAPTPDLEGAQQALRNAVSRCLRAGMRTLVLGGGHETAFGHGAGVLDAFAQESVGIINLDAHLDLRQTDRATSGTPFRQLAQLCDAQSRAFHYACFGVSRAANTQALWREAQWRNVTVVEDLDCHDALAQMTQFIDKVDKIYLTIDLDVLPVWEMPAVSAPAALGVPLIQVLRLIEPVCRSGKLQAADLVEFNPRFDEDGAAARVAARLGWQIAHWWR
What is the function of this protein?
Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.
What are the official names of this protein?
Formimidoylglutamase, Formiminoglutamase, Formiminoglutamate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: RL36_BURMA
Sequence: MKVMASVKRICRNCKIIKRKGVVRVICSSDPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: RS19_COXBR
Sequence: MPRSTNKGPFVDHHLMKKVDQAQKEGSKRPIKTWSRRSMVVPEMVGLTIAIHNGRQHVPVYISENMVGHKLGEFAITRTFRAHSGDRKAKKEGEK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: HSPB2_MOUSE
Sequence: MSGRTVPHAHPATAEYEFANPSRLGEQRFGEGLLPEEILTPTLYHGYYVRPRAARAGEGARAGASELRLSEGKFQAFLDVSHFTPDEVTVRTVDNLLEVSARHPQRLDRHGFVSREFCRTYVLPADVDPWRVRAALSHDGILNLEAPRGGRHLDTEVNEVYISLLPAPPDPEEEEEIARVEP
What is the function of this protein?
May regulate the kinase DMPK.
What are the official names of this protein?
Heat shock protein beta-2, HspB2.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes to nuclear foci.
Protein: RL16_RICCK
Sequence: MLAPKKQRFRKAHKGRVVSKAKAGTTLAFGSFGLKSIDSWRVTARQIEAGRKAATRCMKRQGRLWIRIFPDVPVSKKPAEVRMGKGKGSPEFFAVRVAPGRIMFEIAGVEENIAIRALELASTKLPVRTRIVRRYE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: HYP1_HYPJE
Sequence: MKFFAIAALFAAAAVAQPLEDRSNGNGNVCPPGLFSNPQCCATQVLGLIGLDCKVPSQNVYDGTDFRNVCAKTGAQPLCCVAPVAGQALLCQTAVGA
What is the function of this protein?
Contributes to surface hydrophobicity, which is important for processes such as association of hyphae in reproductive structures, dispersal of aerial spores and adhesion of pathogens to host structures.
What are the official names of this protein?
Hydrophobin-1, Hydrophobin I, HFBI.
What is the protein family that this protein belongs to?
Belongs to the cerato-ulmin hydrophobin family.
What are the subcellular locations of this protein?
Secreted, cell wall. Secreted. Note=Secreted in aqueous environment.
Protein: FABZ_POLAQ
Sequence: MSNPIAIDIHKILQLLPHRYPFLLVDRVLEITPRETITALKNVTMNEPFFQGHFPDFPVMPGVLIIEALAQTAALLTFSEERAEDAIYYFAGIDGARFKKPVLPGDQLIMTARLERGRAGIYKFAVQATVDGEIAAEANITCAVRSKGA
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVD_SYNR3
Sequence: MAPLRSSAITQGVQRSPNRAMLRAVGFGDGDFSKPIIGIANGYSTITPCNVGLNDLALRAEAATQAAGGMPQLFGTITVSDGISMGTEGMKYSLVSREVIADAIETACNGQSMDGVLAIGGCDKNMPAAMLAMARMNIPGVFVYGGTIKPGKLGGCDLTVVSAFEAVGQLSSGKIDEAQLTAVEKNACPGAGSCGGMFTANTMSAAIETMGLSLPFSSTMAAEDPEKAESAARSAEVLVEAIAANIRPLDLLTREAFENAISVIMAVGGSTNAVLHLLAIARTAGVPLSIDDFETIRQRVPVICDLKPSGRFVTVDLHNAGGIPQVMKLLLDGGLLHGDCRTVEGKTLREVLADVPSEPPADQEVIRPLSNPLYAKGHLAVLKGNLASEGAVAKISGVKTPVLTGPARVFESEEQCLQAILANQVHAGDVVVVRNEGPVGGPGMREMLAPTAAIVGEGLGDKVALITDGRFSGGTYGLVVGHVAPEAAVGGMIGLVQEGDSITVDAQQQLLQLNVDAAELERRKQAWVKPEPRYRTGVLGKYARLVSSSSKGAVTDQP
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: CIDEC_RAT
Sequence: MDYAMKSLSLLYPRSLSRHVAVSTAVVTQQLVSEPSRETPRARPCRVSTADRKVRKGIMAHSLEDLLGKVQDILKLKDKPFSLVLEEDGTIVETEEYFQALPRDTVFMVLQKGQKWKSPSEQRKKKAQLSLSQKPTKKIDVARVTFDLYKLNPQDFIGCLNVKATLYDTYSLSYDLHCYRAKRIVKEMLRWTLFSMQATGHMLLGTSSYMQQFLDATEEEQPSKAKASLLPACLKMLQ
What is the function of this protein?
Lipid transferase specifically expressed in white adipose tissue, which promotes unilocular lipid droplet formation by mediating lipid droplet fusion (By similarity).  Lipid droplet fusion promotes their enlargement, restricting lipolysis and favoring lipid storage (By similarity).  Localizes on the lipid droplet surface, at focal contact sites between lipid droplets, and mediates atypical lipid droplet fusion by undergoing liquid-liquid phase separation (LLPS) and promoting directional net neutral lipid transfer from the smaller to larger lipid droplets (By similarity).  The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair (By similarity).  Its role in neutral lipid transfer and lipid droplet enlargement is activated by the interaction with PLIN1 (By similarity).  May also act as a CEBPB coactivator in the white adipose tissue to control the expression of a subset of CEBPB downstream target genes, including SOCS1, SOCS3, TGFB1, TGFBR1, ID2 and XDH (PubMed:23233732).  When overexpressed in preadipocytes, induces apoptosis or increases cell susceptibility to apoptosis induced by serum deprivation or TGFB treatment (By similarity).
What are the official names of this protein?
Lipid transferase CIDEC, Cell death-inducing DFFA-like effector protein C, Fat-specific protein FSP27.
What is the protein family that this protein belongs to?
Belongs to the CIDE family.
What are the subcellular locations of this protein?
Lipid droplet. Endoplasmic reticulum. Nucleus. Note=Diffuses quickly on lipid droplet surface, but becomes trapped and clustered at lipid droplet contact sites, thereby enabling its rapid enrichment at lipid droplet contact sites.
Protein: LACC_STAEQ
Sequence: MILTLTLNPSVDISYPLDQFNLDTVNRVSQTSKTAGGKGLNVTRVLSEFGEDVIASGFLGGALGQYIEEQIETTRIKQAFFKIKGETRNCIAILHEGQQTEILEKGPTIELKESEEFKSHLLKLFKETDVAVMSGSLPKGLNTDYYADIVRLAKEQGILTILDSSGQSLEEVLISNVKPTVIKPNIDELSQLLNYKVTNDIKELKAAVSQPIFNDIEWIIVSLGSEGAFAKHNQKFYKVNIPNIKVVNPVGSGDSTVAGIASGLIHQQTDEELLKKANAFGMLNAMEQQTGHINTDKFDEIFKQIEVIEV
What are the official names of this protein?
Tagatose-6-phosphate kinase, Phosphotagatokinase.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
Protein: EFP_VIBCH
Sequence: MATVSTNEFKGGLKIMLDNEPCVILENEYVKPGKGQAFNRVRIRKLLTGKVLEKTFKSGDTAEVADVVDIDLDYLYNDGEFYHFMNNSTFEQLAADAKAVGENAKWLVENNTCMLTLWNGNPIAVTPPNFVELEVTETDPGVKGDTQGTGGKPATLSTGAVVRVPLFVQIGEVIKVDTRSAEYVGRVK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_RICRO
Sequence: MLLSKYFLPVLKEEPSEAQVTSHKLMLRSGMIRQQAAGIYTWLPLGLKVLKNIENIVRLNMNKAGALEVLMPCIQPAHLWMESGRFDNYGKEMLKFQDRHDNTLLFGPTNEDMITDIFRHNIKSYKDLPKNLYHIQWKFRDEIRPRFGVMRGREFLMKDAYSFDINEENAVKTYNQMYKAYINAFRDLGVFAIPVIADNGPIGGNLSHEFHIIAETGESTIYYDKKFKILKDNPDIDVEEIKSWYAAAEEKYEVNKLPISEQEITSSKGIEVGHIFYIGSKYSVNMNALINDEYGKLTPIEMSSYGIGISRLVAAIIEANCDEKGIIWPSSVAPFKVSLINLNIHDSKCVELAEMAYKELSDKNIEVLYDDTEARPGSKFATHDLIGSPHQIIIGPKKAANNIVELKDRKSGVIEDIEVGSLMSVL
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLD2_DEBHA
Sequence: MPHQESITQLKQAIKVWEHEFQRSNNRIPSRSDIKVDPKVYELYKTYKVLKAKTNNVRNIQDKRTLESANIGIDINMSESQSDAEDVEEFNNENSDSSNNKLKNQDTELGPTPQANGKVLSILDIRLTPPDSSPLKNKVGSRSTDTYSNQKDEAPEDTFKTPTKTRVNRINLSELTPTNNRGPRNKSLMQKLEQASSAKNTRIEMHTPERNKVSLLQNMETPQYLAKVNNKFNFDMDDDSNDKDNVVAEDLHTNSSMKIISSIRSNIIDPITPTKSPAPLKFQVSPSPLKPHRLFSFGNNRKLSDIFNDYKNIKEDPDLINSIENEEEAAELDDDDDTIEKDTATNGPKRKRITQKRTTRRWKIKPNTEETKEDKLKNANIHDEVKKLDDEARKNLVDYMEVNNMHEEDETTSEEEYVHQDPNHKDMKGKVKPVRMNYQRLKINDPRIKKFKKRMQNRR
What is the function of this protein?
Has a role in the initiation of DNA replication.  Required at S-phase checkpoint (By similarity).
What are the official names of this protein?
DNA replication regulator SLD2.
What is the protein family that this protein belongs to?
Belongs to the SLD2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SYT_LAWIP
Sequence: MQSDINKNHLTMTEGLTYINESGLKEEESKNIVGYNINGSIIDLFTPLPTITKEVIPITIDSEDGLEMLRHSAAHILAAAVKNLFPTVKISIGPSIENGFYYDFDAERPFTPEDFPAIEAEMQRIINESIPFERIEISKAEALEFFSSLHENYKVEIINSLEDGNITLYRIGNFTDLCKGPHVPNTNFIKAFKLLSVAGAYWRGNENNQMLSRIYATAFPNKKLLKTYLTQLEEAKRRDHRKLGKELNLFEFHEDIAPGMVFWQPNGMLLRTILEDFLRKEHLKRGYQLVQGPQLLRRELWEKSGHYTNYKENMYFTEIEEDVYGIKPMNCVSHMLLYKTHLHSYRELPQRYFELGVVHRHEKSGVLHGLLRVRQFTQDDAHIICMPEQLEEEIIQVITFVRDLMSLFDFNYHIVISTRPEKSIGSDYAWELATSALIQAVEKINLPYSINHGDGAFYGPKIDIKVTDAIGREWQLSTIQCDFTLPERFELEYVGQDGKRHQPVMIHRAIFGSIERFIGILTEHYAGAFPTWLTPIQVKILTVTDAQTPFAKHVYSQLQDVGIRVGLDIRNEKLGFKIREAQLAKIPYILVIGQKELELESVNVRLRTGENIGMQSVTEFIKLVENDCIQPFKRGGMNYRFS
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCP_PONAB
Sequence: MGRRALLLLLLSFLAPWTTIALRPALRALGSLHLPTNPTSLPAVAKNYSVLYFQQKVDHFGFNTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGDNTFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPHCSESIRRSWDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWISETWVNLAMVDYPYASNFLQPLPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLGWSYQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDLRTKNALDPTSVLLARSLEVRHMKNWIRDFYDSAGKQH
What is the function of this protein?
Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin.  This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH (By similarity).
What are the official names of this protein?
Lysosomal Pro-X carboxypeptidase, Proline carboxypeptidase, Prolylcarboxypeptidase, PRCP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S28 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: SELO_XANAC
Sequence: MTHLRFDNRLRQQLPGDPEEGSRRREVSVAWSAVLPTPVAAPSLIAHSAEMAQVLGLDAAEIASAQFAQVFGGNALYPGMQPWAVNYGGHQFGHWAGQLGDGRAISLGEAIGTDGGRYELQLKGAGPTPYSRGADGRAVLRSSIREFLCSEAMHHLGVPTTRALSLVGTGDAVVRDMFYDGHPQREPGAIVCRVAPSFIRFGNFELPSARGDIALLRQWVDFTIARDFPALAGAGEALYAGWFAQVCERTAVMVAHWMRVGFVHGVMNTDNMSILGLTIDYGPYGWVDDYDPDWTPNTTDAQGRRYRFGTQPQVAYWNLGRLAQALAPLFPDQAPLQHGLDRFRDTYLACDRHDTAAKLGLAECRDEDLQLIDALRALMRESEMDMTLTFRGLIDLSPDHPDPAQLREAFYDEDKRVADAPQLQQWLQRYAARLQQDPLPPDARRARMRLANPRYVLRNYLAQQAIDRAEQGDPSGVQELLEVMRHPYDDQPGRDAFAARRPEWARDRAGCSMLSCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: CYB_SETAM
Sequence: MALNLRKNHQILKIINNALIDLPAPSNISTWWNFGSLLGICLITQIVTGLLLAMHYTADTNLAFSSVAHMCRDVQFGWLIRNLHANGASFFFICIYLHIGRGLYYGSYLNKETWNVGVILLLALMATAFVGYVLPWGQMSFWGATVITNLFSAIPYIGQTLVEWAWGGFSVDNPTLTRFFALHFLLPFVIVGLTLVHLTFLHETGSNNPLGIPSDCDKIPFHPYYTIKDILGFALMLSLLVSLALFSPNLLGDPENFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASILVLFLTPLLHTSKLRSMTFRPLSQILFWTLVANVLILTWVGSQPVEHPFIIIGQLASLSYFTIILILFPLAAALENKLLKL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CYB_CEPBA
Sequence: MTNLRKTHPLMKIINHSFIDLPAPSNISAWWNFGSLLGVCLGLQIVTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYLHANGASMFFMCLFMHVGRGLYYGSYTFLETWNIGILLLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGINLVEWIWGGFSVDKATLTRFFAFHFILPFMVTALVMVHLLFLHETGSNNPSGISSDTDKIPFHPYFTIKDILGLAILMLFLMTLVLFMADLLGDPDNYTPANPPKTPPHIKPEWYFLFAYAILRSIPNKLGGVLALMLSILILAIIPMLHTSKQRSMSFRPLSQCLFWMLVANLLTLTWIGGQPVQHPFIIIGQTASILYFLNILILMPLTNIIENKMIKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.