PharMolix/UniProtQA huggingface dataset:
Protein: Y167_ATV
Sequence: MNFEGFFTKEEMEKIKEEHDRDWRVGATYFKFNDDRITIFVFGYVPGDEFEYNMDLVISQIENVQFPVFCFTFYEKFSGEVMHLPVTKFCLNSLANNNEITFVFCDRIEEVKEKEAICTKERVLHMKNLVKEKAKQMLASFKEFDQNFVFREYIRTIKNPPPSCNPD
What are the official names of this protein?
Uncharacterized protein ORF167.
Protein: NDUS7_PONPY
Sequence: MAALSAPGLCGFRILGLRSSVGTAVQARGVHQSVATDGPSSTQPALPKARAVAPKPSSRGEYVVAKLDDLVNWARRSSLWPMTFGLACCAVEMMHMAAPRYDMDRFGVVFRASPRQSDVMIVAGTLTNKMAPALRKVYDQMPEPRYVVSMGSCANGGGYYHYSYSVVRGCDRIVPVDIYIPGCPPTAEALLYGILQLQRKIKRERRLQIWYRR
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity of complex I.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial, Complex I-20kD, CI-20kD, NADH-ubiquinone oxidoreductase 20 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: SYL_BACAN
Sequence: MSFNHQEIEKKWQGYWEENKTFRTPDETEKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNSPAEFTEHNINTFRNQIKSLGFSYDWDREVNTTDPNYYKWTQWIFLKLFEKGLAYVDEVPVNWCPALGTVLANEEIIDGKSERGGHPVERRPMRQWMLKITAYGDRLLEDLDELDWPESLKDMQRNWIGRSEGAEVHFNIDGTDEKFTVFTTRPDTLFGASYCVLAPEHALVADITTADQKEAVEAYINSVKMKSDLERTELAKEKTGVFTGAYAVNPVNGEKLPIWIADYVLATYGTGAVMAVPAHDERDYEFASTFNLPMKEVVKGGDITKEAYTGDGAHVNSAFLDGLNKEEAIAKMIEWLEVTSAGNQKVTYRLRDWLFSRQRYWGEPIPVIHWEDGTMTAVKEEELPLVLPKTENIRPSGTGESPLANIDEWVNVVDPETGKKGRRETNTMPQWAGSCWYYLRYIDPNNSEALVDPEKVKQWLPVDIYIGGAEHAVLHLLYARFWHKVLYDIGVVPTKEPFQQLFNQGMILGENNEKMSKSKGNVVNPDDIVASHGADTLRLYEMFMGPLDASIAWSENGLDGARRFLDRVWRLFVQDNGELSEKITDAPNKDLEKAYHQTVKKVTEDYAELRFNTAISQMMVFINDAYKAETLPKEYVEGFVKMIAPVAPHIGEELWSKLGYNETITYASWPTFDESKLVEDEVEIVVQVMGKVRAKLTMSKDASKDEMEKLALEAIQDQIEGKTVRKVIVVPGKLVNVVAN
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NINJ2_MOUSE
Sequence: MESDRETIHLQHRHSMRGGNQRIDLNFYATKKSVAESMLDVALFMSNAMRLKSVLQQGPFAEYYTTLVTLIIVSLLLQVVISLLLVFIAILNLNEVENQRHLNKLNNAATILVFITVVINIFITAFGAHHAASMAARTSSNPI
What is the function of this protein?
Homophilic cell adhesion molecule that promotes axonal growth.  May play a role in nerve regeneration and in the formation and function of other tissues.
What are the official names of this protein?
Ninjurin-2, Nerve injury-induced protein 2.
What is the protein family that this protein belongs to?
Belongs to the ninjurin family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PSRP_STRMK
Sequence: MSTIRPVFYVSDGTGITAETIGHSLLTQFSGFSFITDRMSFVDDPEKAREACARIQAAGERYQVRPIVVNSCVDQSLSLILADSGALMLDVFAPFIEPLERELASPRLARVGQAHGMVDFDTYHRRINAMNFALTHDDGIAVNYDDADVILVAVSRAGKTPTCIYLALHYGVRAANYPLTDEDLESDRLPPRLRNYRRKLFGLTIDPDRLQQIRQERRPNSRYANLETCKREVAAAEVMFQMERIPTLSTTHTSIEEISSKVLATLGLQRELY
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: RIMP_CHESB
Sequence: MQDDRIIRETGAAARVAAIVMPVLDALGYRLVRVRLSAQDGLTLQIMAERPDGTMTVDDCEEVSRAVSPALDVEDPIDSAYQLEISSPGIDRPLVRLSDFQAALGHLAKVETSVMVDGRKRFRGQIVGCTGETLTIERDKVAEGEAPLAEIPLDAISDAKLVLTDALIREALKKDKEERRQRKKARRRGEKGGVGDDGTAGEEQPDSAREGPARSASEGE
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_DICNV
Sequence: MTEYLFTSESVSEGHPDKIADQISDAVLDAILEKDLKARVACETLVKTGMVVIAGEIGTSTWVDLEDLVRKTICTIGYTHSEMGFDGRTCAVLNAIGKQSGDIAQGVDRGEAKLQGAGDQGLMFGYACTETPTLMPAPITYAHRLVEKQAQLRHSGALPWLRPDAKSQITFRYRDNTIVGVDAIVLSTQHSEEISLKELTEAVREEIIAPIVPSKWIDKKTRFHINPTGKFVIGGPLGDCGLTGRKIIVDTYGGAARHGGGAFSGKDPSKVDRSAAYAARYVAKNVVAAGLATRCEVQLSYAIGIAEPTSIMVNTFGTGTIDDAEIVRRVQAVFDLTPYGIIEMLDLVRPIYQKTAVYGHFGRELPQFTWEKTDRSDALQQA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MET3_COCIM
Sequence: MANPPHGGILKDLLARDAPRHAELEAEAETLPALLLTERHLCDLELILNGGFSPLEGFMNEKDYNGVVENVRLADGNLFSIPITLDASKETIDGLGLQPGSRVTLRDFRDDRNLAILTIDDIYQPDKQKEAKEVFGGDPEHPAVKYLYDQTNEYYIGGKVEAVNKLNHYDYVGLRFTPAELRLHFDKLGWTRVVAFQTRNPMHRAHRELTVRAARARQANVLIHPVVGLTKPGDIDHFTRVRVYEALLPRYPNGMAVLGLLPLAMRMGGPREAIWHAIIRKNHGATHFIVGRDHAGPGKNSKGEEFYGPYDAQHAVEKYRHELGIEVVEFQQLTYLPDTDEYKPRDEIPAGVKTLDISGTELRKRLRLGTHIPEWFSYPEVVKVLRESNPPRSKQGFTVFLTGYQNSGKAAIARALQVTLNQQGGRSVSLLLGDTVRHELSAELGFSREDRHKNIQRIAFVAAELTKAGAAVIAAPIAPYEESRQQARETISSAGTFFLVHVATSLEYAEKTDKRGVYARARRGEIKGFTGVDDPYETPQKPDITVDIEKQTVRSAVHEIILLLESQGFLEKA
What is the function of this protein?
Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP.  Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids.
What are the official names of this protein?
Sulfate adenylyltransferase, ATP-sulfurylase, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the APS kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOCOS_ASPOR
Sequence: MQAKSKTESRAEYCTGYSEDVDVIREREYPFLKDTTYLDHAGTTLYPKSLIDSFARDLTSNLFGNPHSRSSSSQLSTQRIDDIRLRALRFFNADPDEFDLVFVANATAAIKLVVDVFRDSSPQGFWYGYFIDAHTSLVGAREIAERGHRCFLTSGEVERWIADLATDQKNFPRLFAYPGQSNLNGRRSPMQWCKKIRDGSSGAGNVYTLLDAASLVSTSPLDLSDASAAPDFTALSFYKIFGFPDLGALIVRKSAAGIIKKRKFFGGGTVDMVLAQGMPWHAKKSTIHECLEDGTLPFHNIIALDSALSTHGRLFGSMSNVSFHTRYLAKRLHNRLAAMTHFNGQKVCHLYMSPESDFDNSTQGPIIAFNIRNSSGAWIGKSEVERLANVKKIHIRSGSHCNSGGTATSLGWTGPELLRNFSAGLRCGDDHDVMDGRPTGILRVSLGAVSNLRDIDAFARFIDEFYIEKEPEFVSLVPPMEVVLQEPSFYVESLSVYPIKSCGAFKVPDGQRWEIKREGLAWDREWCLIHQGTGAALSMKKYPRMALIRPVIDLERGVLRITCGSDSKELEVSLRREITNLVTTSLCQSAKSSNVCGDRVVVQAYSSPTVASFFSNFLGVPCTLARFPPQISTRISNPTRSSRRSQRALMPGSFPEDPSPTSEQPPILLSNESPILLISRSSVNRLNENIKYNPRPSYSTPAKAVEADVFRANIVVAENLHQLANAERPYIEDTWESFSVGPEQLCFDVLGSCQRCQMVCVDPYTGTRREEPYSTLVKTRKINSKIVFGRHTSLSNMELSQGAGKPKSCTVMVGDVVTPQIA
What is the function of this protein?
Sulfurates the molybdenum cofactor.  Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.
What are the official names of this protein?
Molybdenum cofactor sulfurase, MCS, MOS, MoCo sulfurase, Molybdenum cofactor sulfurtransferase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily.
Protein: PKNA_MYCTU
Sequence: MSPRVGVTLSGRYRLQRLIATGGMGQVWEAVDNRLGRRVAVKVLKSEFSSDPEFIERFRAEARTTAMLNHPGIASVHDYGESQMNGEGRTAYLVMELVNGEPLNSVLKRTGRLSLRHALDMLEQTGRALQIAHAAGLVHRDVKPGNILITPTGQVKITDFGIAKAVDAAPVTQTGMVMGTAQYIAPEQALGHDASPASDVYSLGVVGYEAVSGKRPFAGDGALTVAMKHIKEPPPPLPPDLPPNVRELIEITLVKNPAMRYRSGGPFADAVAAVRAGRRPPRPSQTPPPGRAAPAAIPSGTTARVAANSAGRTAASRRSRPATGGHRPPRRTFSSGQRALLWAAGVLGALAIIIAVLLVIKAPGDNSPQQAPTPTVTTTGNPPASNTGGTDASPRLNWTERGETRHSGLQSWVVPPTPHSRASLARYEIAQ
What is the function of this protein?
Protein kinase that regulates many aspects of mycobacterial physiology, and is critical for growth in vitro and survival of the pathogen in the host (PubMed:25713147).  Is a key component of a signal transduction pathway that regulates cell growth, cell shape and cell division via phosphorylation of target proteins such as FtsZ, Wag31, GlmU, PstP, EmbR and Rv1422 (PubMed:15985609, PubMed:16817899, PubMed:19121323, PubMed:21190553, PubMed:21423706).  Also catalyzes the phosphorylation of the proteasome alpha-subunit (PrcA) and unprocessed proteasome beta-subunit (pre-PrcB), which results in the inhibition of processing of pre-PrcB and assembly of the proteasome complex, and thereby enhances the mycobacterial resistance to H(2)O(2); PknA thus plays an important role in the oxidative stress response by impeding the formation of holo-proteasome in M. tuberculosis under H(2)O(2) stress (PubMed:25224505).  Shows a strong preference for Thr versus Ser as the phosphoacceptor.
What are the official names of this protein?
Serine/threonine-protein kinase PknA.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=The majority of the cells displays PknA expression at the membrane perimeter along the length of the cell, whereas a minor population shows PknA to localize at either or both poles (uni- and bipolar; 16 and 14%, respectively) and occasionally to both the poles and the midcell (12%).
Protein: PRPC_BACSU
Sequence: MLTALKTDTGKIRQHNEDDAGIFKGKDEFILAVVADGMGGHLAGDVASKMAVKAMGEKWNEAETIPTAPSECEKWLIEQILSVNSKIYDHAQAHEECQGMGTTIVCALFTGKTVSVAHIGDSRCYLLQDDDFVQVTEDHSLVNELVRTGEISREDAEHHPRKNVLTKALGTDQLVSIDTRSFDIEPGDKLLLCSDGLTNKVEGTELKDILQSDSAPQEKVNLLVDKANQNGGEDNITAVLLELALQVEEGEDQC
What is the function of this protein?
Protein phosphatase that dephosphorylates PrkC and EF-G (elongation factor G, fusA).  prpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, PrpC's primary role being possibly to counter the action of PrkC.  May be involved in sporulation and biofilm formation.  Does not seem to be involved in stress response.  Dephosphorylates phosphorylated CgsA, EF-Tu and YezB (PubMed:19246764).
What are the official names of this protein?
Protein phosphatase PrpC.
Protein: RIBB_CHRVO
Sequence: MNANTDILSLRVHAALDALRRGLPVIVADDADRENEADLILAADTLTVPEMARMIRDGSGIVCLCLTPERAERLQLPPMAAENGSRYGTAFTVAIEAAQGVTTGVSAADRTTTIRAAIHPDAKPGDLVRPGHVYPIVARAGGVRERRGHTEASVELARLAGFSPAGVLCELMNPDGTMMRGQQVQDYAERHDLPQLSVAELAEWLQREPA
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: RIMM_SHEDO
Sequence: MSDNQQPVVLGKLGSSHGIKGWLKITAYTDSVEGIFDYVPWLIKDQGVWREVKVTQWRFQGKAVVAELEGVTTREQAQMLTNCEIAILPEQMKELDDNDFYHRDLIGCEVTNVNGYNLGIVDQIVETGSNDVLLVKANAKDAFGKVERMIPFVTEQFIKQVDLQGKQIVVDWDPDF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_RUEPO
Sequence: MPRYALKVEYLGTPFAGWQRQKDLPSVQGAIETALARLEPGPHTIAAAGRTDAGVHGLGQVAHCDLTRDWDPFRLSEALNYHLKPQPVAITAAARVAEDWHARFSATERQYLFRLLMRRAPATHDAGLVWQVGHRLDARAMQAAADLLLGRHDFTTFRSSICQAASPVKTLDELRVEAVESFSGPEIRFHVRARSFLHNQVRSFVGTLERVGAGAWAPEDVRSALEARDRAACGPVCPPQGLYLARVGYPEPVFAADRSAAS
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: FDHD_XANOR
Sequence: MTNSSSRSVRAGSVVRTVCRHRGGRSAMVQDMVAAEMPVAFIYNGVQFAVMMATPEDLEDFALGFSLSEGIVDHAQDLRVIAVETFLEGASLQIDIPPERAAALDQRRRNLDGRSGCGVCGNESIEAVLRVPPVLNSSLQIDVDALAHALDALHARQPIAAQTGAVHAAGWADAQGNVQLVREDVGRHNALDKLIGALARARIDASQGFAVVTSRASYEMAMKATQARIPLLAAISAPTALAISLADSAGLTLIGFARNHDCVVYSHPQRLNLGVAVGETA
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity.  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
What are the official names of this protein?
Sulfur carrier protein FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T2R31_PANPA
Sequence: MTTFLPIIFSSLVVVIFVIGNFANGFIALVNSIEWFKXQKISFADQILTALAVSRVGLLWVLLLNWYSTVLNPAFYSVEVRTTAYNVWAVTGHFSNWLATSLSIFYLLKIANFSNFIFLHLKRRVKSVILVMLLGPLLFLACQLFMINMKEIVRTKEYEGNMTWKIKLRSAVYLSDATVTTLGNLVPFTLTLLCFLLLICSLCKHLKKMQLHGKGSQDPSTKVHIKVLQTVISFLLLCAIYFLSIMISVWSFGSLKNKPVFMFCKAIRFSYPSIHPFILIWGNKKLKQTFLSVLRQVRYWVKGEKPSSP
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 31, T2R31, Taste receptor type 2 member 44, T2R44.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y2146_IDILO
Sequence: MLAVVSPAKNLDYESDLPELNVTQPRLLDNAEELVEVCRQLSPQQLGSLMKISDKLAGLNAARFEEWQRPFNENNARPAMYAFNGDVYTGLDAASLNSEAIGTAQKQLRILSGLYGVLRPLDLMQPYRLEMGTKLDNPKGKNLYEYWGDSITQMLNKDLAELGSSTLVNLASNEYFSAVKPKVLNADIITPVFKDEKNGQYKVISFYAKKARGLMARFILNQKPKSVSDLKEFDANGYSFNEAMSSDKQLVFCRAEQK
What are the official names of this protein?
UPF0246 protein IL2146.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: FADB_ECODH
Sequence: MLYKGDTLYLDWLEDGIAELVFDAPGSVNKLDTATVASLGEAIGVLEQQSDLKGLLLRSNKAAFIVGADITEFLSLFLVPEEQLSQWLHFANSVFNRLEDLPVPTIAAVNGYALGGGCECVLATDYRLATPDLRIGLPETKLGIMPGFGGSVRMPRMLGADSALEIIAAGKDVGADQALKIGLVDGVVKAEKLVEGAKAVLRQAINGDLDWKAKRQPKLEPLKLSKIEATMSFTIAKGMVAQTAGKHYPAPITAVKTIEAAARFGREEALNLENKSFVPLAHTNEARALVGIFLNDQYVKGKAKKLTKDVETPKQAAVLGAGIMGGGIAYQSAWKGVPVVMKDINDKSLTLGMTEAAKLLNKQLERGKIDGLKLAGVISTIHPTLDYAGFDRVDIVVEAVVENPKVKKAVLAETEQKVRQDTVLASNTSTIPISELANALERPENFCGMHFFNPVHRMPLVEIIRGEKSSDETIAKVVAWASKMGKTPIVVNDCPGFFVNRVLFPYFAGFSQLLRDGADFRKIDKVMEKQFGWPMGPAYLLDVVGIDTAHHAQAVMAAGFPQRMQKDYRDAIDALFDANRFGQKNGLGFWRYKEDSKGKPKKEEDAAVEDLLAEVSQPKRDFSEEEIIARMMIPMVNEVVRCLEEGIIATPAEADMALVYGLGFPPFHGGAFRWLDTLGSAKYLDMAQQYQHLGPLYEVPEGLRNKARHNEPYYPPVEPARPVGDLKTA
What is the function of this protein?
Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle.  Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA.  It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
Protein: RP07_MONPV
Sequence: MVFQLVCSTCGKDISHERYKLIIRKKSLKDVLVSVKNECCRLKLSTQIEPQRNLTVQPLLDIN
What is the function of this protein?
Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates.  Responsible for the transcription of early, intermediate and late genes.  DNA-dependent RNA polymerase associates with the early transcription factor (ETF), itself composed of OPG118 and OPG134, thereby allowing the early genes transcription.  Late transcription, and probably also intermediate transcription, require newly synthesized RNA polymerase.
What are the official names of this protein?
DNA-directed RNA polymerase 7 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the poxviridae DNA-directed RNA polymerase 7 kDa subunit family.
Protein: RL30_ECO24
Sequence: MAKTIKITQTRSAIGRLPKHKATLLGLGLRRIGHTVEREDTPAIRGMINAVSFMVKVEE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: ATPB_CORK4
Sequence: MTTALSEQQTGLSGRVARVIGPVVDVEFPRGELPALFNALTVDVDLEAVAKTITLEVAQHLGDNIVRAVSMAPTDGLIRGAEVKDTGKPISVPVGDTVKGHVFNALGDCLDEPGLGRDGEQWSIHRKPPAFDQLEGKTEILETGIKVIDLLTPYVKGGKIGLFGGAGVGKTVLIQEMITRIAREFSGTSVFAGVGERTREGTDLFLEMEEMGVLQDTALVFGQMDEPPGVRMRVALSGLTMAEYFRDVQHQDVLLFIDNIFRFSQAGSEVSTLLGRMPSAVGYQPTLADEMGELQERITSTKGRSITSLQAVYVPADDYTDPAPATVFAHLDATTELDRSIASKGIYPAVNPLTSTSRILEPGIVGEEHYQVAQRVINILQKNKELQDIIAILGMDELSEEDKITVQRARRIERFLGQNFFVAEKFTGLPGSYVPLKDTIDAFRRICDGEYDAYPERCFNGLGGLDDVEAEYKKLQEK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GUAAB_SULIY
Sequence: MFDPASFVKEIGPQLKQKVGNERVLAAVSGGVDSTTAAVLAYNLLGNKVIPVLIDTGFLRKNEAEKIKAYLSNVLPNLIVVDERETFTSEIEGMEEAEAKRKKFRELFYSSISSLMRKFNAKYLMQGTIAADWVETQGGIKTQHNVLVQIGIDTEKEWGFTLIEPLADLYKNEVRELARYLKLPKEISERQPFPGPGLLVRTIGKLTREKLEVVREANDIVEKYLDPFNYSQYFAVSFESDGNFVILDGIDAFLYKARATGVKGDVRAYGNIAKVECSDINAAKSFVDTLVKYDITHVLCSLDERSNGKYSIAIRAVITEDFMTADYARIPKEVLEKISSEILQKIPNVKEVLYDVTSKPPATIEFE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing] subunit B, GMP synthetase.
Protein: ATPG_BRUA4
Sequence: MPSLKDLRNRIASVKATQKITKAMQMVAAAKLRRAQEAAEAARPYSQRMGAVLANIAQNVTGEDAPALMAGTGKDDVHLLVVCTAERGLCGGFNSQIARLARDHARKLLAEGKTVKIITVGKKGADILRREFASLIIDHVNLREVKQLAFVHADQIGHKVIELFEQGEFDVCTLFYSEFKSVIAQIPTAQQIIPASAGDVAQAETAGDAIYEYEPDPAAILSTLIPRNISVQIFRALLENVAGEMGAKMSAMDNATRNAGDMINKLSITYNRQRQAQITKELIEIISGAEAL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GATA_STRA3
Sequence: MSFNNQSIDQLHDLLVKKEISATELTKATLEDIHAREQAVGSFITISDDMAIAQAKEIDDKGIDADNVMSGIPLAVKDNISTKGILTTAASKMLYNYEPIFDATAVEKLYAKDMIVIGKANMDEFAMGGSTETSYFKKTNNAWDHSKVPGGSSGGSAAAVASGQVRLSLGSDTGGSIRQPASFNGIVGMKPTYGRVSRFGLFAFGSSLDQIGPMSQTVKENAQLLTVISGHDVRDSTSSERTVGDFTAKIGQDIQGMKIALPKEYLGEGIAPGVKETIIKAAKHLEKLGAVIEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRTENYKNLDDIYVNTRSEGFGDEVKRRIMLGTFSLSSGYYDAYYKKAGQVRSLIIQDFEKVFADYDLILGPTAPTTAFDLDSLNHDPVAMYLADILTIPVNLAGLPGISIPAGFDKGLPVGMQLIGPKFSEETIYQVAAAFEATTDYHKQQPKIFGGEN
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: MURD_STRPM
Sequence: MKVISNFQNKKILILGLAKSGEAAAKLLTKLGALVTVNDSKPFDQNPAAQALLEEGIKVICGSHPVELLDEDFEYMVKNPGIPYDNPMVKRALAKEIPILTEVELAYFVSEAPIIGITGSNGKTTTTTMIADVLNAGGQSALLSGNIGYPASKVVQKAIAGDTLVMELSSFQLVGVNAFRPHIAVITNLMPTHLDYHGSFEDYVAAKWMIQAQMTESDYLILNANQEISATLAKTTKATVIPFSTQKVVDGAYLKDGILYFKEQAIIAATDLGVPGSHNIENALATIAVAKLSGIADDIIAQCLSHFGGVKHRLQRVGQIKDITFYNDSKSTNILATQKALSGFDNSRLILIAGGLDRGNEFDDLVPDLLGLKQMIILGESAERMKRAANKAEVSYLEARNVAEATELAFKLAQTGDTILLSPANASWDMYPNFEVRGDEFLATFDCLRGDA
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EXT2_MOUSE
Sequence: MCASVKSNIRGPALIPRMKTKHRIYYVTLFSIVLLGLIATGMFQFWPHSIESSSDGGVEKRSIREVPVVRLPTDSPIPERGDLSCRMHTCFDVYRCGFNPKNKIKVYIYPLKKYVDDAGVPVSSAISREYNELLTAISDSDYYTDDINRACLFVPSIDVLNQNPLRIKETAQALAQLSRWDRGTNHLLFNMLPGAPPDYNTALDVPRDRALLAGGGFSTWTYRQGYDVSIPVFSPLSAEMALPEKAPGPRRYFLLSSQMAIHPEYREELEALQAKHQESVLVLDKCTNLSEGVLSVRKRCHQHQVFDYPQVLQEATFCTVLRGARLGQAVLSDVLQAGCVPVVIADSYILPFSEVLDWKRASVVVPEEKMSDVYSILQNIPQRQIEEMQRQARWFWEAYFQSIKAIALATLQIINDRIYPYAAISYEEWNDPPAVKWASVSNPLFLPLIPPQSQGFTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEESLWPKIRVPLKVVRTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDRLVGYPGRLHLWDHEMNKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWVDTHMNCEDIAMNFLVANVTGKAVIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKFASVFGTMPLKVVEHRADPVLYKDDFPEKLKSFPNIGSL
What is the function of this protein?
Glycosyltransferase required for the biosynthesis of heparan-sulfate.  The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone.  Appears to be a tumor suppressor.  Required for the exosomal release of SDCBP, CD63 and syndecan.
What are the official names of this protein?
Exostosin-2, Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase, Multiple exostoses protein 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 47 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein. Golgi apparatus, cis-Golgi network membrane; Single-pass type II membrane protein. Note=The EXT1/EXT2 complex is localized in the Golgi apparatus.