PharMolix/UniProtQA huggingface dataset:
Protein: GSA1_STACT
Sequence: MGYEKSIEAYKKAEQLMPGGVNSPVRAFKSVDMPAIFMDHGKGSKIYDIDGNEYIDYVLSWGPLILGHENPQVIENLHKAVDKGTSFGASTLEEIKLAELVIDRVPSIEKVRMVSSGTEATQDTIRLARGYTGRDKIVKFEGCYHGHSDSLLIKAGSGVATLGLPDSPGVPEGTAKSTITVPYNDLDAIRKAFELYGDDIAGVIVEPVAGNMGVVPPVEGFLQGLRDITNEYGSLLIFDEVMTGFRVGYNCAQGYFDVIPDLTCLGKVIGGGLPVGAFGGKKEIMDEIAPVGTIYQAGTLSGNPLAMTSGYETLSQLTPESYEYFNELGDMLEDGLKKVAAKHNVPMTVNRAGSMIGYFLNDGPVTNFEQANKSDLKLFSEMYREMAKEGVFLPPSQFEGTFLSTAHTKEDIERTIEAFDKTFERITNK
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase 1, GSA 1, Glutamate-1-semialdehyde aminotransferase 1, GSA-AT 1.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADD_PROA2
Sequence: MRLALFGGSFDPPHNAHLALCLCARELLDIDKLIISVSNNPLKENRSASNAHRLAMAELLVSEINATGRIAEVSRWELERSGPSYTIDLLTRIGQLYPEEPVTLLIGEDNFRGFRQWKSWQEILERCYVVVFRRPLEHAAFDDAYAHLPGIPDRHQVRFIDFDFQLSSTAIRYAIATGEPYAHLVPPSIADYIASRHLYSERS
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: T2MZ_METTF
Sequence: MIDNFKEIRLDFKDELKKITGKEVEFPKYTTQIINLANQNAQGTRPRVVGQMSDLIHECPDKSYEGWKKWYLEHYSDRIEKATKKISKMIENMKAAMELIDEEMIRKWVEDLVITKTAEGLIIQEIILKTIAEEAGLEWRLATSKEESKNIDGFIGSTPVSIKPMSYESMRPTVREEIDIQTIFYKKPKNSRYLYIYHNLNI
What is the function of this protein?
A P subtype restriction enzyme that recognizes the double-stranded sequence 5'-CTAG-3' and cleaves after C-1.
What are the official names of this protein?
Type II restriction enzyme MthZI, R.MthZI, Endonuclease MthZI, Type-2 restriction enzyme MthZI.
Protein: RH24_ORYSJ
Sequence: MSKRPKLGGFSIPRPTSYSFERSQPPQRLYVPADDPDLDDIAFSDDAAAPSDAPPAGGGGAAGDEEEIDPLDAFMAEIQEEIRAPPPAPKPEALRRADSDDEDDPVESFLRAKKDSGLALAADAMHAGYDSDEEVYAAAKAVDAGMMEYDSDDNPIVVDKKKIEPIPPLDHSTIEYEPFNKDFYEEKPSVSGMSEQEVADYMKSLAIRVSGFDVPRPIKSFADCGFPVQLMNAIAKQGYEKPTTIQCQALPIVLSGRDIIGIAKTGSGKTAAFVLPMIVHIMDQPELEKEEGPIGVVCAPTRELAHQIYLEAKKFAKPYNLRVAAVYGGVSKFDQFKELKAGCEIVIATPGRLIDLLKMKALKMFRATYLVLDEADRMFDLGFEPQIRSIVGQIRPDRQTLLFSATMPYKVERLAREILTDPIRVTVGQVGSANEDIKQVVNVLPSDAEKMPWLLEKLPGMIDDGDVLVFAAKKARVDEIESQLNQRGFRIAALHGDKDQASRMETLQKFKSGVYHVLVATDVAARGLDIKSIKTVVNFDIAKEMDMHIHRIGRTGRAGDKDGTAYTLITQKEVRFAGELVHCLIAAGQDVPNELMDLAMKDGRFRANRDSRKGGKKSGKGKGGGGGGGGGSGARGRGRGVRGVDFGLGIGYNAESGSVPAPRSAALNSLKTGMMQNFKSSFVSASSSNTPSNSAPSRGAPSSFVRPALRGFVSGGTIGGDANQARAVLPAPSFVPASRPAENTVENANPNPESSRDRTRERKRPSGWDR
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase 24.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family.
Protein: CSD_STAEQ
Sequence: MAEHSFDVKAVIKDFPILEQKVNNKRLAYLDSTATSQTPVQVLNVLDDYYKRYNSNVHRGVHTLGSLATDGYENARETVRRFINAKYFEEIIFTRGTTASINIVAHSYGDANISEGDEIVVTEMEHHANIVPWQQLAKRKNATLKFIPMTKDGELQLDDIKATINDKTKIVAIAHVSNVLGTINDVKTIAKIAHEHGAVISVDGAQSAPHMALDMQDIDADFYSFSGHKMLGPTGIGVLYGKRELLQNMEPVEFGGDMIDFVSKYDATWADLPTKFEAGTPLIAQAIGLAEAIHYIENLGFNAIHQHEKELTEYAYEQMLTIDGLEIYGPPKDRRAGVITFNLADIHPHDVATAVDTEGVAVRAGHHCAQPLMKWLGVSSTARASFYVYNTKEDVDQLVQALKQTKEFFSYEF
What is the function of this protein?
Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
What are the official names of this protein?
Probable cysteine desulfurase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
Protein: CCD47_CANLF
Sequence: MKASLAFCVVLLVFGSVSEAKFDDFEDEEDIVEYDDNDFAEFEDVTEDSVTESPQRVITTEDDEDETTVELEGQDENQEGDFEDADTQEGDTESEPYDDEEFEGYEDKPDTSSSKNKDPITIVDVPAHLQNSWESYYLEILMVTGLLAYIMNYIIGKNKNSRLAQAWFNTHRELLESNFTLVGDDGTNKEATSTGKLNQENEHIYNLWCSGRVCCEGMLIQLRFLKRQDLLNVLARMMRPVSDQVQIKVTMNDEDMDTYVFAVGTRKALVRLQKEMQDLSEFCSDKPKSGAKYGLPDSLAILSEMGEVTEGMMDTKMVHFLTHYADKIESVHFSDQFSGPKIMQEEGQPLKLPDTKRTLLFTFNVPGSGNTYPKDMEALLPLMNMVIYSIDKAKKFRLNREGKQKADKNRARVEENFLKLTHVQRQEAAQSRREEKKRAEKERIMNEEDPEKQRRLEEAALRREQKKLEKKQMKMKQIKVKAM
What is the function of this protein?
Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes (PubMed:36261528).  The MPT complex takes over after the SEC61 complex: following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex, the MPT complex occludes the lateral gate of the SEC61 complex to promote insertion of subsequent transmembrane regions (PubMed:36261528).  Within the MPT complex, the PAT subcomplex sequesters any highly polar regions in the transmembrane domains away from the non-polar membrane environment until they can be buried in the interior of the fully assembled protein (PubMed:36261528).  Within the PAT subcomplex, CCDC47 occludes the lateral gate of the SEC61 complex (PubMed:36261528).  Involved in the regulation of calcium ion homeostasis in the ER (By similarity).  Required for proper protein degradation via the ERAD (ER-associated degradation) pathway (By similarity).  Has an essential role in the maintenance of ER organization during embryogenesis (By similarity).
What are the official names of this protein?
PAT complex subunit CCDC47, Coiled-coil domain-containing protein 47.
What is the protein family that this protein belongs to?
Belongs to the CCDC47 family.
Protein: VP40_EBOZM
Sequence: MRRVILPTAPPEYMEAIYPVRSNSTIARGGNSNTGFLTPESVNGDTPSNPLRPIADDTIDHASHTPGSVSSAFILEAMVNVISGPKVLMKQIPIWLPLGVADQKTYSFDSTTAAIMLASYTITHFGKATNPLVRVNRLGPGIPDHPLRLLRIGNQAFLQEFVLPPVQLPQYFTFDLTALKLITQPLPAATWTDDTPTGSNGALRPGISFHPKLRPILLPNKSGKKGNSADLTSPEKIQAIMTSLQDFKIVPIDPTKNIMGIEVPETLVHKLTGKKVTSKNGQPIIPVLLPKYIGLDPVAPGDLTMVITQDCDTCHSPASLPAVIEK
What is the function of this protein?
Plays an essential role virus particle assembly and budding (PubMed:16719918, PubMed:33673144).  Acts by interacting with viral ribonucleocapsid and host members of the ESCRT (endosomal sorting complex required for transport) system such as host VPS4, PDCD6IP/ALIX, NEDD4 or TGS101 (PubMed:15892969, PubMed:16719918, PubMed:23637409, PubMed:25786915, PubMed:26753796, PubMed:27489272).  The interaction with host E3 ubiquitin ligase SMURF2 also facilitates virus budding (PubMed:33673144).  May play a role in immune cell dysfunction by being packaged into exosomes that can decrease the viability of recipient cells (via RNAi suppression and exosome-bystander apoptosis) (PubMed:27872619).
What are the official names of this protein?
Matrix protein VP40, Ebola VP40, eVP40, Membrane-associated protein VP40.
What is the protein family that this protein belongs to?
Belongs to the filoviridae matrix protein VP40 family.
What are the subcellular locations of this protein?
Host cytoplasm. Host cell membrane. Virion membrane; Peripheral membrane protein. Host late endosome membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Host endomembrane system; Peripheral membrane protein. Secreted, extracellular exosome. Note=In virion, localizes on the inner side of the membrane. In the host cell, it is found associated with virus-induced membrane proliferation foci and probably also in multivesicular bodies. These VP40-enriched membrane clusters are then redistributed to the plasma membrane where budding takes place.
Protein: Y338_AFV2P
Sequence: MDLDWLMKCKCKKMLKRLTVKVSGYVVAKITKKGSEETKLKPLVMGKHNQILNLQSLLNAFVGNSSGVTTSSYGEGITLLGANGESVAELAFLTVTPQPTAGGGEVIFTGLDISNSAYTTTQQVLTTESSGYDIEIATADLSFTKNSDEQLYMTWVISFTVTSNPDNVTIVPSLNMSFTVPPNGYYSAPSLCQYTPDNGNLKAQSATGQSSPTTSNPSGYELTTLVTSLLFTWLIYSSSPGASLEYLAFVGTNSLALAVETNTMGSVSGVQYTATTIGPNNFVTGNYIFVESSNNWTVYTRVSPNANDSTISPVFVNAVYSGLFSECTFQGIVIQFTT
What are the official names of this protein?
Uncharacterized protein ORF338.
Protein: AROE_RUTMC
Sequence: MYKFAVFGNPIKHSLSPNIHIQFAQQTGFEVSYDKILAPIDDFSSSAQAFINQGANGFNITVPFKLDAFKFASELTLNAQIAGAVNTIKIEQDKIIGENTDGIGLVNDLTHNLGIELKDKVILILGAGGATQGILLPLLKQQPNHVMIANRTPFKAIKLAKDFAKFGKTCGFDLDKIKHDPVNIIINATSTSLYGKMPDIASGVANNAICYDLMYGKQTPFMDWATINHGSMISDGLGMLIEQAAVAFEFWTGVKPNTEQVLSNLRS
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: NHX1_ORYSJ
Sequence: MGMEVAAARLGALYTTSDYASVVSINLFVALLCACIVLGHLLEENRWVNESITALIIGLCTGVVILLMTKGKSSHLFVFSEDLFFIYLLPPIIFNAGFQVKKKQFFRNFMTITLFGAVGTMISFFTISIAAIAIFSRMNIGTLDVGDFLAIGAIFSATDSVCTLQVLNQDETPFLYSLVFGEGVVNDATSIVLFNALQNFDLVHIDAAVVLKFLGNFFYLFLSSTFLGVFAGLLSAYIIKKLYIGRHSTDREVALMMLMAYLSYMLAELLDLSGILTVFFCGIVMSHYTWHNVTESSRVTTKHAFATLSFIAETFLFLYVGMDALDIEKWEFASDRPGKSIGISSILLGLVLIGRAAFVFPLSFLSNLTKKAPNEKITWRQQVVIWWAGLMRGAVSIALAYNKFTRSGHTQLHGNAIMITSTITVVLFSTMVFGMMTKPLIRLLLPASGHPVTSEPSSPKSLHSPLLTSMQGSDLESTTNIVRPSSLRMLLTKPTHTVHYYWRKFDDALMRPMFGGRGFVPFSPGSPTEQSHGGR
What is the function of this protein?
Vacuolar antiporter that acts in low affinity electroneutral exchange of protons H(+) for cations such as Na(+) or K(+) across membranes (PubMed:14988485).  Plays important roles in the transport of Na(+) and K(+) accumulated in the cytoplasm into vacuoles, and is involved in salt stress tolerance (PubMed:14988485).
What are the official names of this protein?
Sodium/hydrogen exchanger 1, Na(+)/H(+) exchanger 1, OsNHX1.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: RPOC_ACISJ
Sequence: MKSLLDLFKQFTPDEHFDAIKIGMASPEKIRSWSFGEVKKPETINYRTFKPERDGLFCAKIFGPIKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIDLAAPCAHIWFLKSLPSRLGLVLDMTLRDIERVLYFEAYVVTDPGMTPLKKFGIMSEDDYDAKRKEYGDEFVAKMGAEGIKELLEGIDIEIEIEKLRGDLTGSEVKVKKNAKRLKVLEAFKKSGIKPEWMILEVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNSRLRRLLELKAPEIIARNEKRMLQEAVDSLLDNGRRGKAMTGANKRALKSLADMIKGKSGRFRQNLLGKRVDYSGRSVITVGPTLKLHQCGLPKLMALELFKPFIFSRLEAMGIATTIKAAKKEVEAGTPVVWDILEEVIKEHPVMLNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSVEAQLEARTLMLASNNVLFPASGEPSIVPSQDVVLGLYHATREKINGKGEGLVFADTGEVQRALDAGEAELHAKISVRLTEWTKDKATGEFVPETKLVDTTVGRALLSEILPKGLPFSNLNKALKKKEISKLINASFRKCGLKDTVVFADKLLQNGFRLATHAGFSVAIDDMLVPPQKAEILARAEAEVKEIEQQYVSGLVTAGERYNKVVDIWGKAGDDVSKVMMDQLKVQKTIDRNGKEVNEESFNAIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVTQDLVVTEDDCGTSNGSLMRAIVEGGEVIESLRDRILGRTAAEEVLHPETRAVLAQPGRMLDEDLIEELEAAGVDEVKVRTALTCETRYGLCAKCYGRDLGRGGLINLGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAVASSVEAKSNGIIGFNATMRYVTNTKGELVVIARSGEIIIQDEHGRERERHKVPYGATLTVKADQNIKAGTILANWDPLTRPIITEYAGTVKFENVEEGLTVAKQVDEVTGLSTLVVIDPKRRGSAKVVRPQVKLVDADGKEVKIPGTDHSVTIGFQVGALIQVRDGQEVGPGEVLARIPMEGQKTRDITGGLPRVAELFEARSPKDKGMLAEMTGTISFGKETKGKVRLQITDPDGKVWDELVPKEKNVLVHEGQVVNKGELIVDGPADPQDILRLLGIEELSRYIVDEVQDVYRLQGVKINDKHIEVIVRQMLRRVVVENPGESTYIAGEQVERSEILNTNEALQAEGKLPATYSNVLLGITKASLSTDSFISAASFQETTRVLTEAAIMGKRDELRGLKENVIVGRLIPAGTGLAYHQARKAKDAMDEAERRAIADAEAAELASAGTHDAAAEIDGSADTAD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: SYA_PARMW
Sequence: MAAAASSSSAASAPRSGEDIREAFLNFYAERGHQRMASASLIPEDPTVLLTIAGMLPFKPVFLGQQQRPAPRATSSQKCIRTNDIENVGRTARHHTFFEMLGNFSFGDYFKQQAIEWAWELSTQVYGIDPRNLVVSVFREDDEAEQIWRDVVGVNTKRIIRMDEADNFWASGPTGPCGPCSEIYYDFKPELGDDGIDLEDDDRFIEFYNLVFMQYNRDAEGNLTPLANRNIDTGMGLERMAQILQKVPNNYETDLIFPLIQAAADLACVDYAQLDDKGKTSLKVIGDHSRAVTQLICDGVTASNLGRGYILRRLLRRVVRHGRLLGIDKPFLVTMGEAAIDLLKGAHPGVIERQEVILAELQREEARFLETLERGEKLLAEVLASRPTQISGAQAFELYDTYGFPLELTQEIAEEQRITVDLDGFEVAMEEQRQRAKAAAVSIDLTLQDAIEQVAGDQPATAFKGYDALDHPSTVQALVVNGAPASTASAGDVVQVVLDSTPFYGEGGGQVGDRGSLSGVDVIVAIDSVSRSRDVFVHSGRMERGHLAVGDTVNAQVDRSCRRRAQANHTATHLLQAALKQVVDPGIGQAGSLVDFDRLRFDFHCPTAVTAEQLAQIETLINGWIAEAHCLEVQEMAIDQAKAAGAVAMFGEKYADVVRVVDVPGVSMELCGGTHVANTAEIGLFKIVAESGVAAGIRRIEAVAGPAVLAYLNERDAVVKQLGDRFKAQPAEIVDRVTALQEELKATGKALAAAQAELAVAKAGALAAKAEAVGEFQLLVERLDGVEGAGLQGAAQSLADQLGDGAAVVIGGLPDPGDLGKVILVAAFGKQVIAAKLQAGKFIGGIAKQCGGGGGGRPNLAQAGGRDGAALPGALAAARSELAAALPQS
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOBD_ECO27
Sequence: MTITDLVLILFIAVLLAFAIYDQFIMPRRNGPTLLAIPLLRRGRIDSVIFVGLIVILIYNSVTNHGALITTWLLSALALMGFYIFWIRVPKIIFKQKGFFFANVWIEYSRIKAMNLSEDGVLVMQLEQRRLLIRVRNIDDLEKVYKLLVSTQ
What are the official names of this protein?
UPF0266 membrane protein YobD.
What is the protein family that this protein belongs to?
Belongs to the UPF0266 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SCKL1_ARATH
Sequence: MASLLIFPHLHHFDSSLDRREVLVVRHSQASRRFLTPKASINGSGITNGAAAETTSKPSRKGRKKKQTSTVIEKDNTETDPELNPELADYDDGIEFPYDDPPLVCCFGAVQKEFVPVVRVHDNPMHPDMYSQWKMLQWDPPEFGRAPGGPPSNVAISHVRLGGRAAFMGKVGEDDFGDELVLMMNQERVQTRAVKFDENSKTACTRVKIKFKDGKMMAETVKEPPEDSLFASELNLAVLKEARIFHFNSEVLTSPTMQSTLFTAIQWSKKFGGLIFFDLNLPLPLWRSRNETRKLIKKAWNEANIIEVSQQELEFLLDEDYYERRRNYTPQYFAEDFDQTKNRRDYYHYTPEEIKSLWHDKLKLLVVTDGTLRLHYYTPTFDGVVIGTEDVLITPFTCDRTGSGDAVVAGIMRKLTTCPEMFEDQDVMERQLRFAVAAGIIAQWTIGAVRGFPTESATQNLKEQVYVPSMW
What is the function of this protein?
Required for proper chloroplast development, most likely through regulating plastid-encoded polymerase (PEP) dependent chloroplast transcription.  Acts as a component of the transcriptionally active plastid chromosome that is required for plastid gene expression.
What are the official names of this protein?
Fructokinase-like 1, chloroplastic, PEP-associated protein 6, pfkB-type carbohydrate kinase family protein 2.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: AR1BB_XENLA
Sequence: MAFHSFLLEPITCHAWNKDATQIAFCPNSHDVHIYKKDGVKWTKIHELKEHNGQVTGIDWAPESNRIVTCGTDRNAYVWTLRNNVWKPTLVILRINRAARCVKWSPKENKFAVGSGSRLISICYFEQENDWWVCKHIKKPIRSTVLSLDWHPNNVLLAAGSSDFKSRIFSSYIKEVEERPAPTPWGSKMPFGELMFESSSSCGWVHSVCFSNSGDRMAWVSHDSTICIADATKKMRVTSLITDTLPLLCVTFITENSLVAAGHDCYPVLYTYDEAQGTLSFGGKLDVPKQSSQRGMTARERFQNLDKKASSDTNNITLDSLHKNSISQISVLSGGKAKCSKFCTTGLDGGMCIWDVKSLESALKDLKIK
What is the function of this protein?
Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF).  The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (By similarity).  In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA.  The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) (By similarity).
What are the official names of this protein?
Actin-related protein 2/3 complex subunit 1B-B.
What is the protein family that this protein belongs to?
Belongs to the WD repeat ARPC1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Nucleus.
Protein: RL17_BACAN
Sequence: MAYRKLGRTSAQRKAMLRDLATDLIINERIQTTETRAKELRSVVEKMITLGKRGDLHARRQAAAFIRNEVANAETGQDALQKLFADVAPRYAERQGGYTRIAKIGPRRGDAAPMVIIELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: UPP_CUTAK
Sequence: MELNVMDHPLVSHKLTLLRSVDTPSPVFRQLVEELVTLMAYEGTREVRIEPTTVTTPLTATEGVALTRPKPLVVPILRAGLGMLEGMMRLIPSAEVGFVGMARDEETLQPMTYAERLPKDLSGRQCYVLDPMLATGGSLGGTVEFLVRRGADHITCLCILAAPEGIENFRKLVRDLDVPCHLIVAGLDDHLDEHGYIVPGLGDAGDRLYGLAE
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: MAOC_FLATR
Sequence: MISLNSSFLERSSVTGGSRTQSQSLRLSARRPVVTSMLNSNSLPERNVSVSVDSAVRDVNAPVAVEVDRSVGEKPFAAVGGGVEDMYGEDTATEDHYITPWSVSVASGYSLLRDPHHNKGLAFTEKERDAHFLRGLLPPVVVNHDLQVKKMMHNIRQYQVPLQRYQAMMDLQQRNERLFYKLLIENVEELLPIVYTPTVGEACQKYGSIFENSQGLFISLKDKGRILEILKNWPHKKIQVIVVTDGERILGLGDLGCQGMGIPVGKLALYTALGGVRPSACLPITIDVGTNNEKLLNDDEFYIGLKQKRAAGQEYAELMNEFMSAVKQNYGENLLIQFEDFANHNAFDLLEKYRTTHLVFNDDIQGTASVVLGGLISALKLVGGSLADQKFLFLGAGEAGTGIAELIALEISKQTNIPLEESRKKVWLVDSKGLIVRSRLDSLQHFKKPWAHDHEPVNEFLDAIKTIRPTVLIGSSGTGQTFTKEVVETMSSLNEKPIILALSNPTSQSECTAEQAYTWSEGRAIFASGSPFKPVEYNGKLYVSGQANNAYIFPGFGLGLIISGAIRVHDDMLLAASEAPAEQVTQEHFDKGLIFPPFTSIRKISAHIAAKVAAKAYELGLASRLPQPENLVAYAESCMYSPKYRIYR
What is the function of this protein?
The chloroplastic ME isoform decarboxylates malate shuttled from neighboring mesophyll cells.  The CO(2) released is then refixed by ribulose-bisphosphate carboxylase.  This pathway eliminates the photorespiratory loss of CO(2) that occurs in most plants.
What are the official names of this protein?
NADP-dependent malic enzyme, chloroplastic, NADP-ME.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL29_COXBN
Sequence: MNVNDLRNKTKAELKKELLELLKEQFNLRMQKGGGEAPRPHLFKRVRRDIARVKTLLGEKERNNE
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: DTNK_SALTY
Sequence: MKMIVIADDFTGSNDTGVQLAKKGARTEVMLSASQKPSRRADVLVINTESRAMPADQAASAVYAALSPWCETSPAPLVYKKIDSTFRGNIGAEVTAAMRASQRKLAVIAAAIPAAGRTTLEGKCLVNGVPLLETEFASDPKTPIVSSRIAEIVALQSEIPVYEVFLQDVRRGGLSALLTAYAAEGEGIIVVDAVEERDLTLIAQAACEQPSMPLLVGAAGLANALPVELFMQDRQRLPVLVVAGSMSEATRRQVDNALCRGRAEVVDIDAARMVSDSAEQEIASVVEQACALLSQHRHTILRTSRRAEDRQLIDALCEKSAMSRQQLGERLSQRLGVVTLNIIEQARIGGLFLTGGDIATAVAGALGAEGYRIQSEVAPCIPCGTFVNSEIDDLPVITKAGGFGSDSTLCDALYYIEEMYCGD
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of D-threonate to D-threonate 4-phosphate (PubMed:27402745).  Can also phosphorylate 4-hydroxy-L-threonine, with lower efficiency.  This side reaction may serve to deal with the toxicity of 4-hydroxy-L-threonine by converting it into 4-hydroxy-L-threonine 4-phosphate, a useful product that can be used by PdxA2 (PubMed:27402745, PubMed:27294475).
What are the official names of this protein?
D-threonate kinase.
What is the protein family that this protein belongs to?
Belongs to the four-carbon acid sugar kinase family.
Protein: ARNT_SALA4
Sequence: MMKSIRYYLAFAAFIALYYVIPVNSRLLWQPDETRYAEISREMLASGDWIVPHFLGLRYFEKPIAGYWINSLGQWLFGATNFGVRAGAILTTLLAAALVAWLTFRLWRDKRTALLASVIFLSLFAVYSIGTYAVLDPMIALWLTAGMCCFWQGMQATTRTGKIGMFLLLGATCGLGVLTKGFLALAVPVVSVLPWVIVQKRWKDFLLYGWLAVLSCFVVVLPWAIAIARREADFWHYFFWVEHIQRFAMSDAQHKAPFWYYLPVLLAGSLPWLGLLPGALKLGWRERNGAFYLLGWTIMPLLFFSIAKGKLPTYVLSCFAPIAILMARFVLHNVKEGVAALRVNGGINLVFGIIGIVAAFVVSSWGPLKSPVWTHIETYKVFCVWGVFTVWAFVGWYSLCHSQKYLLPAFCPLGLALLFGFSIPDRVMESKQPQFFVEMTQAPLASSRYILADNVGVAAGLAWSLKRDDIMLYGHAGELRYGLSYPDVQDKFVKADDFNAWLNQHRQEGIITLVLSIAKDEDISALSLPPADNIDYQGRLVLIQYRPK
What is the function of this protein?
Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase, 4-amino-4-deoxy-L-arabinose lipid A transferase, Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase, Undecaprenyl phosphate-alpha-L-Ara4N transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 83 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: WECF_ECOK1
Sequence: MTVLIHVLGSDIPHHNRTVLRFFNDALAATSGHAREFMVAGKDDGLSDSCPALSVQFFPGKKSLAEAVIAKAKANRQQRFFFHGQFNPKLWLALLSGGIKPSQFFWHIWGADLYELSSGLRYKLFYPLRRLAQKRVGCVFATRGDLSFFAKTHPKVRGELLYFPTRMDPSLNTMANDRQREGKMTILVGNSGDRSNEHIAALRAVHQQFGDTVKVVVPMGYPPNNEAYIEEVRQAGLELFSEENLQVLSEKLEFDAYLTLLRQCDLGYFIFARQQGIGTLCLLIQAGIPCVLNRENPFWQDMTEQHLPVLFTTDDLNEDIVREAQRQLASVDKNTIAFFSPNYLQGWQRALAIAAGEVA
What is the function of this protein?
Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis.
What are the official names of this protein?
TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase, 4-alpha-L-fucosyltransferase, TDP-Fuc4NAc:lipid II Fuc4NAc transferase, Fuc4NAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 56 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SYI_METTP
Sequence: MIVEVPGQYNPKNVEDEVREFWHREDTYHKVRRLRSGGRRFFFVDGPPYTTGRIHLGTAWNKVIKDSILRYMSMRGYDLKDRAGWDMHGLPIEVKVEEHLGFRSKRDIESYGVDRFIEQCKSFALRQKDEMTEQFKSLGVWLDWDNPYMTLKNEYIEAAWWTLKRAHERGLLERGLRVVNWCPRCQTAIADSEVEYWDESDPSIYVKFPVEGEDNTYIVIWTTTPWTIPANVAVAVHKDFMYSKVRAWRRDGTYEILIMATDLIENVLKQGRYVDYEILESMRGEDLLSLTYKNPLQDLVPAQRDIVHRVHLADFVTAENTGIVHIAPGHGLEDYELGLEKRLPIFCPVGEDGRYTSEAGKKYEGKYVRDANPEVVEDLMERGALLASGELVHRYGHCWRCKTPIIFIATRQWFIGISELRDQMLKEIERVSWYPDWAGSARFKDWISNARDWCISRQRYWGIPLPIWICRSCGAMDVIGTAAELEARAGRPVEDLHRPAVDDVRLRCSCGGAMERVPDVFDVWFDSAVASWATLNFPRDEEEFRVWWPADFITEGHDQTRGWFYSQLGASMVAFGRAPYKSVLMHGFTLDEQGRKMSKSIGNVVHPEDVVERYGADTLRFYVLSSNAPWEDLHFSWEGAMNVNRMLNILWNAYRFPLPYMVLDRFDISKADTSKYDLRPEDRWIISRVNSLAKEIEENMSGYMLHRATRSLQEFVLEDLSRWYIQLVRPRTWIETEDPDKLAAYATLYNVMSTLVKLMAPFTPFLAESIYQNLVRGLDPSAPESVHMCDWPGYREDLIDKGLEESMSYVREISEAAANARQKGGRKLRWPVSRIIIASDEQLDLRDLLHVLRTQTNSKEVIILPPGEKPEMNLEISVVQKKIGPVFKGESRDVVEALTSMNPKEVKRIIESGEPLEWKGRSYMITEEMVEFREIPPANLIPAEFSKGTVYVDVSLTDELRAEGYAREIIRRIQDMRKDLDLKVDEMIRVSVALNSNEVVDLVSGWRDYISSEVRATLLRIGNDLDLEGELTKDWEVDGVKIRVSVARA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.