PharMolix/UniProtQA huggingface dataset:
Protein: SOMT1_PAPSO
Sequence: MATNGEIFNTYGHNRQTATVTKITASNESSNGVCYLSETANLGKLICIPMALRAAMELNVFQLISKFGTDAKVSASEIASKMPNAKNNPEAAMYLDRILRLLGASSILSVSTTKKSINRGGDDVVVHEKLYGLTNSSCCLVPRQEDGVSLVEELLFTSDKVVVDSFFKLKCVVEEKDSVPFEVAHGAKIFEYAATEPRMNQVFNDGMAVFSIVVFEAVFRFYDGFLDMKELLDVGGGIGTSVSKIVAKYPLIRGVNFDLPHVISVAPQYPGVEHVAGDMFEEVPKGQNMLLKWVLHDWGDERCVKLLKNCWNSLPVGGKVLIIEFVLPNELGNNAESFNALIPDLLLMALNPGGKERTISEYDDLGKAAGFIKTIPIPISNGLHVIEFHK
What is the function of this protein?
Methyltransferase involved in the biosynthesis of the benzylisoquinoline alkaloid noscapine (PubMed:22535422, PubMed:22653730, PubMed:29610307).  Catalyzes the conversion of (S)-scoulerine to (S)-tetrahydrocolumbamine (PubMed:22535422, PubMed:22653730).  Can convert (S)-tetrahydrocolumbamine to tetrahydropalmatine (PubMed:22535422).  Can convert (S)-norreticuline to (S)-norcodamine (PubMed:22535422).  Can convert (S)-reticuline to (S)-codamine (PubMed:22535422).  Substrate preference is (S)-scoulerine > (S)-tetrahydrocolumbamine > (S)-norreticuline > (S)-reticuline (PubMed:22535422).
What are the official names of this protein?
Scoulerine-9-O-methyltransferase 1, PsSOMT1, Norreticuline 3-O-methyltransferase SOMT1, O-methyltransferase 1, Reticuline 3-O-methyltransferase SOMT1, Tetrahydrocolumbamine 2-O-methyltransferase SOMT1.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. COMT subfamily.
Protein: PG10_MYCTO
Sequence: MSWVMVSPELVVAAAADLAGIGSAISSANAAAAVNTTGLLTAGADEVSTAIAALFGAQGQAYQAASAQAAAFYAQFVQALSAGGGAYAAAEAAAVSPLLAPINAQFVAATGRPLIGNGANGAPGTGANGGPGGWLIGNGGAGGSGAPGAGAGGNGGAGGLFGSGGAGGASTDVAGGAGGAGGAGGNASMLFGAAGVGGVGGFSNGGATGGAGGAGGAGGLFGAGGEGGSGGSGNLTGGAGGAGGNAGTLATGDGGAGGTGGASRSGGFGGAGGAGGDAGMFFGSGGSGGAGGISRSVGDGAAGGAGGAPGLIGNGGNGGNGGASTGGGDGGPGGAGGIGVLIGNGGNGGXGGTGATLGKAGIGGTGGVLLGLDGFTPPASTSPLHTLQQDVINMVNDPFQTLTGRPLIGNGANGTPGTGADGGAGGWLFGNGGNGGQGTIGGVNGGAGGAGGAGGILFGTGGTGGSGGPGATGLGGIGGAGGAALLFGSGGAGGSGGAGAVGGNGGAGGNAGALLGAAGAGGAGGAGAVGGNGGAGGNGGLFANGGAGGPGGFGSPAGAGGIGGAGGNGGLFGAGGAGGNGGLFGAGGTGGAGSHSTAAGVSGGAGGAGGDAGLLSLGASGGAGGSGGSSLTAAGVVGGIGGAGGLLFGSGGAGGSGGFSNSGNGGAGGAGGDAGLLVGSGGAGGAGASATGAATGGDGGAGGKSGAFGLGGDGGAGGATGLSGAFHIGGKGGVGGSAVLIGNGGNGGNGGNSGNAGKSGGAPGPSGAGGAGGLLLGENGLNGLM
What are the official names of this protein?
Uncharacterized PE-PGRS family protein PE_PGRS10.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PE family. PGRS subfamily.
Protein: NOP9_LEPMJ
Sequence: MPKEHKKRGRRDEQKKRKRDADDDATAKRHKKDDVDAQFQPLDAAHQLHHGGVGEDGELTRPGEVQFYGMLDEDEQEFFKNVDDQLDRNEFASPDERAQWLKNVFKEAEGKELKIANSQSCSRVLERLILLSTPGQLKNIFEKFNGHFLNLVQHRFASHCCEALFLQAAPVVTQELANPERLQTPPSSNPDHIFVSMENLFLFTLAELQEHLGFLMTDRFASHVLRVLLVVLSGSPLERQSKSVLQSKRKEKVDVTGAEKGREWLAEKRAVPQSFLEALEKVINNCVSGMEPHYLRSLATHPLGNPTLQLLLKLELSHFGKSRAKDEKSLIHRLLPDDPIAEGTDSAAFINGLVYDPIGSRLLETIIENAPGKLFKAIYGEFFKERMGSLSRNEIAGYVAGKILERLGKDDLEEAMRQIVDQIPSLVERNRTAIIKTLIERCVARGVDTASIKAQLETAYGGSNGFEVIRILKLSEEDGKPGGEHKQQSPEKLHGSLLAQTMMSVEGPLGNLVFDSLANLSPELSVQLARDPPASRTLQAALTSPNASVIFRRKMIQQFYGKVGELALDPSASRVIDAIWNGTAGLAFIRERIAEELAENEGSLRESYVGRAVWRNWRMDLYKRKRNDWVKQSRYTAGNDGFQSFPESDGDASNSQTRAGKHMTAIELARQKHAAAKAAAQGKKDMKKEKTERHGTGSNSSAVGTKGRVVAQ
What is the function of this protein?
RNA-binding nucleolar protein required for pre-rRNA processing.  Involved in production of 18S rRNA and assembly of small ribosomal subunit (By similarity).
What are the official names of this protein?
Nucleolar protein 9, Pumilio domain-containing protein NOP9.
What is the protein family that this protein belongs to?
Belongs to the NOP9 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: MNMA_MYCUA
Sequence: MKVLAAMSGGVDSSVAAARMVDAGHDVVGVHLALSTAPGALRTGSRGCCSKEDASDARRVADVLGIPFYVWDFAERFKEDVIDDFVSSYARGETPNPCIRCNQRIKFSALYAKALALGFDVVVTGHYARLSEGRLRRAVDQDKDQSYVLAVLTAEQLRHAMFPIGDTPKPQIREEASRRGLAVADKPDSHDICFIPSGNTQTFLGERIGVRRGTVVDAAGAVLATHDGVHGFTIGQRKGLGIPGPGPDGRPRYVTAIDAETGTVRVGDVADLQVHALTGRAPIFTAGTAPTGPLECAVQVRAHGETTSAVAELVGDELSVRLHSPLRGVARGQTLVLYRPDPDGDEVLGSATITATSACSPVS
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_OPITP
Sequence: MANPKRKQSKRRSANRRAANAFIAPEFAKDPTDGSAFRPHRVNPKNGMYRGRQVLNVEV
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: CSLH2_ORYSI
Sequence: MAVVAAAAATGSTTRSGGGGGEGTRSGRKKPPPPPLQERVPLGRRAAWAWRLAGLAVLLLLLALLALRLLRHHGGAGGDAGVWRVALVCEAWFAALCALNVSAKWSPVRFVTRPENLVAEGRTPSTTAAEYGELPAVDMLVTTADPALEPPLVTVNTVLSLLALDYPRAGERLACYVSDDGCSPLTCHALREAAGFAAAWVPFCRRYGVAVRAPFRYFSSSSSPESGGPADRKFLDDWTFMKDEYDKLVRRIKNTDERSLLRHGGGEFFAEFLNVERRNHPTIVKTRVSAVMTNAPIMLNMDCDMFVNNPQAVLHAMCLLLGFDDEASSGFVQAPQRFYDALKDDPFGNQMECFFKRFISGVQGVQGAFYAGTGCFHRRKAVYGVPPNFNGAEREDTIGSSSYKELHTRFGNSEELNESARNIIWDLSSKPMVDISSRIEVAKAVSACNYDIGTCWGQEVGWVYGSLTEDILTGQRIHAMGWRSVLMVTEPPAFMGSAPIGGPACLTQFKRWATGQSEIIISRNNPILATMFKRLKFRQCLAYLIVLGWPLRAPFELCYGLLGPYCILTNQSFLPKASEDGFSVPLALFISYNTYNFMEYMACGLSARAWWNNHRMQRIISVSAWTLAFLTVLLKSLGLSETVFEVTGKDKSMSDDDDNTDGADPGRFTFDSLPVFIPVTALAMLNIVAVTVGACRVAFGTAEGVPCAPGIGEFMCCGWLVLCFFPFVRGIVWGKGSYGIPWSVKLKASLLVAMFVTFCKRN
What is the function of this protein?
Thought to be a Golgi-localized beta-glycan synthase that polymerize the backbones of noncellulosic polysaccharides (hemicelluloses) of plant cell wall.
What are the official names of this protein?
Cellulose synthase-like protein H2, OsCslH2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. Plant cellulose synthase-like H subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: SORD_PENRW
Sequence: MQAASAFATCLLASVGGNSSAVAFPNQANYSTLVAPYNFDLLTTPSAIVWPQDTQQVAAAVKCAVDSDIKVQPKSGGHNYGNYGSTTGELSVNLDNLQHFSMDETSWTARLGPGNRLGRVTELMYNNGGRHVPHGTTFTVGLGGHATVGGAGAASRMHGLLLDYVEEVEVVLANSSIVRASKSHNEDLFFAVRGAASSVGIVTDFSIRTEPVPVSSVTYSYIWEGTDPAARAEVFLTWQSLLAGGSLPQHMAYDLVATANSMILGGAYFGSQEDFEAFNLSSHFKVAPDVAHIKTYTNFFDFSAAASAQTKAAGIASPSHFYAKSLVFNQQTLIPDDAAEEVFKYLATTKNGTDLYAVTFAALGGAVRDVSASETAFYHRDASYFMFSFGRTSGDLTDTTVQFLDGLSEVLTSGQPDAYYGQYVGNVDPRQSTDKALTGYYGKNLHRLQQIKSAVDPNDVFHNQQSIPPLS
What is the function of this protein?
FAD-linked oxidoreductase; part of the gene cluster that mediates the biosynthesis of sorbicillinoids, a diverse group of yellow secondary metabolites that restrict growth of competing pathogenic fungi but not of bacteria (PubMed:25580210, PubMed:28618182).  Sorbicillinoids biosynthesis requires the action of two PKSs (PubMed:25580210).  SorA iteratively combines three acetyl units and the growing chain is modified by the ketoacyl reductase subunit, and optional by the enoyl reductase subunit in the second cycle (PubMed:25580210).  The polyketide is then handed over to the PKS SorB, which adds three more acetyl units, and two methyl groups (PubMed:25580210).  SorB releases an aldehyde, which undergoes spontaneous cyclization resulting in the formation of sorbicillin or 2',3'-dihydrosorbicillin (PubMed:25580210).  The monooxygenase sorC oxidizes sorbicillin and 2',3'-dihydrosorbicillin to 2',3'-dihydrosorbicillinol and sorbicillinol, respectively (PubMed:28618182).  The oxidoreductase sorD further converts sorbicillinol into oxosorbicillinol (PubMed:28618182).  Sorbicillinol is the building block for the other sorbicillinoids such as disorbicillinol, bisvertinolon, and dihydrobisvertinolone (By similarity).
What are the official names of this protein?
FAD-linked oxidoreductase sorD, Sorbicillinoid biosynthetic cluster protein D.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
Protein: RPN2_MOUSE
Sequence: MAPPGSSAVFLLALTITASVQALTPTHYLTKQDVERLKASLDRPFTDLESAFYSIVGLSSLGVQVPDVKKACTFIKSNLDPSNVDSLFYAAQSSQVLSGCEISVSNETKELLLAAVSEDSPIAQIYHAVAALSGFGLPLASNEALGALTARLGKEETVLATVQALQTASHLSQQADLRNIVEEIEDLVARLDELGGVYLQFEEGLELTALFVAATYKLMDHVGTEPSMKEDQVIQLMNTIFSKKNFESLSEAFSVASAAAALSQNRYHVPVVVVPEGSTSDTQEQAILRLQVSNVLSQPLAQAAVKLEHAKSAATRATVLQKTPFSLVGNVFELNFKNVKLSSGYYDFSVRVEGDSRYIANTVELRVKISTEVGITNVDLSTVDKDQSIAPKTTRVTYPAKAKGTFIADSHQNFALFFQLVDVNTGAELTPHQTFVRLHNQKTGQEVVFVAEPDNKNVYKFELDTSERKIEFDSASGTYTLYLIIGDATLKNPILWNVADVVIKFPEEEAPSTVLSQSLFTPKQEIQHLFREPEKRPPTVVSNTFTALILSPLLLLFALWIRIGANVSNFTFAPSTVIFHLGHAAMLGLMYIYWTQLNMFQTLKYLAVLGTVTFLAGNRMLAQHAVKRTAH
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit, Ribophorin II, RPN-II, Ribophorin-2.
What is the protein family that this protein belongs to?
Belongs to the SWP1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Endoplasmic reticulum membrane; Multi- pass membrane protein.
Protein: RL6_GEOSE
Sequence: MSRVGKKPIEIPAGVTVTVNGNTVTVKGPKGELTRTFHPDMTITVEGNVITVTRPSDEKHHRALHGTTRSLLANMVEGVSKGYEKALELVGVGYRASKQGKKLVLSVGYSHPVEIEPEEGLEIEVPSQTKIIVKGADKQRVGELAANIRAVRPPEPYKGKGIRYEGELVRLKEGKTGK
What is the function of this protein?
It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity).  This protein binds to the 23S rRNA, and is important in its secondary structure.
What are the official names of this protein?
50S ribosomal protein L6, BL10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RNH2_ACIAC
Sequence: MRSRKSLPRVEQAHLPWHPPGLVAGVDEAGRGPLAGPVVAAAVILDELQPIEGLADSKTLTAARREALFDEIRAKALCCSVAEATVEEIDTLNILQATMLAMRRAVAGLRLKPVRVLVDGNRLPPLDVPAEAIVKGDALVQAISAASILAKVTRDRWCAQLHEAYPHYGFASHKGYGTAEHMAALQAHGACPEHRRSFAPVAAAVQRTVVMQATATIVTTVETTVSVRPAAPRAAEGLHA
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPD_HERAR
Sequence: MQITDQEALLRCIEHREIFHDEMLTLFRRIMSGEMSPVMMAAIITGLRVKKESIGEITAAAEVMREFATKVPLTDTTNLLDIVGTGGDGANTFNISTASMFVAAAAGARIAKHGGRSVSSSSGSADALDALGANINLKPELVAESIAQTGIGFMFAPNHHAAMKHAAAVRKELGVRTIFNILGPLTNPAGAPNILMGVFHPDLVGIQVRVLQRLGAQHAIVVWGRDNMDEVSLGAATMVGELIDGKIREYEIHPEDFGLPMIASRNLRVANAAESKTRILEVLANTAGPARDIVTLNAGTALYAAGVASSISAGLQLAREAIASGAARAKMEQFVRVTQELGSKA
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: HOG1_PHANO
Sequence: MAEFVRAQIFGTTFEITSRYTDLQPVGMGAFGLVCSAKDQLTSQAVAIKKIMKPFSTPVLSKRTYRELKLLKHLRHENIISLSDIFISPLEDIYFVTELLGTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGVVHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQKYDVEVDVWSAGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIHTICSENTLRFVQSLPKRERQPLANKFKNAEPAAVDLLENMLVFDPKKRVRAEQALAHPYLAPYHDPTDEPVAEEKFDWSFNDADLPVDTWKIMMYSEILDYHNVDAAAQEGENGGS
What is the function of this protein?
Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment.  Controls osmotic regulation of transcription of target genes (By similarity).
What are the official names of this protein?
Mitogen-activated protein kinase HOG1, MAP kinase HOG1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. HOG1 sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CAPP_SALSV
Sequence: MNEQYSALRSNVSMLGKVLGETIKDALGEHILDRVETIRKLSKSSRAGNEANRQELLTTLQNLSNDELLPVARAFSQFLNLANTAEQYHSISPKGEAASNPEVIARTLRKLKNQPDLNDATIKKAVESLSLELVLTAHPTEITRRTLIHKMGEINNCLKQLDNTDIADYERHQVMRRLRQLIAQSWHTDEIRKQRPSPVDEAKWGFAVVENSLWQGVPNYLRELNEQLEENLGYKLPVDFVPVRFTSWMGGDRDGNPNVTADITRHVLLLSRWKATDLFLKDIHVLVSELSMVDATPELLALVGEEGASEPYRYLMKKLRARLMATQSWLEARLKGEKLPKPDGLLTQNEQLWEPLYACYQSLQACGMGIIANGELLDTLRRVKCFGVPLVRIDIRQESTRHTEALGEITRYLGIGDYESWSEADKQAFLIRELNSKRPLLPRNWEPSNDTREVLETCKVIAEAPKGSIAAYVISMAKTPSDVLAVHLLLKEAGIGFAMPVAPLFETLDDLNNADDVMTQLLNIDWYRGLIQGKQMVMIGYSDSAKDAGVMAASWAQYQAQDALIKTCEKAGIELTLFHGRGGSIGRGGAPAHAALLSQPPGSLKGGLRVTEQGEMIRFKYGLPEVTVSSLSLYTSAILEANLLPPPEPKDSWRHIMDELSVISCETYRGYVRENKDFVPYFRSATPEQELGKLPLGSRPAKRRPTGGVESLRAIPWIFAWTQNRLMLPAWLGAGTALQKVVEDGKQSELEAMCRDWPFFSTRLGMLEMVFSKADLWLADYYDQRLVAKTLWPLGKELRDLLEEDIKVVLAIANDSHLMADLPWIAESIQLRNVYTDPLNVLQAELLYRSRLTEEQGKSPDPRVEQALMVTIAGVAAGMRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: TEG5_EHV1B
Sequence: MDQHHGARGGAPIRRPRRSIESRSHPFRATGNTQRTYSTPRLSYRDGLSGRTASRDPQEQASNQDESSNPSTSNAQQSTSFWGYLRRVFSDDVPAQPQAPRPRADFAPPAGEESSSEEEEEEGPAQAPLDEEDQLMYADQYSVGDSSDENDEEEDPRLGSDYPTSAESSEYHDHGEMVAGAGAESESETDIDAEEEEEDDEDDEDDMEVIRDESYRLPRTWLDKSIRLMDEALAQSSELSKAITKSTRSLYDSQFAPGGRGYTQTATPSRRLVQLSRAGMYDSDKIVMTGDYMEVDDDPDSAYQSWVRAIRHPLAMNPSWEETISNHTNPSFSTDIDYDIDELIEKNLARTPPVFEGLLDSAEFFYKLPMLYTYATITQDEAYEERLAWSNTQALHGHEQSSWQALLVYYSRGGMYVSPTQEPRGIWRRALKQAMALQLKMCVLGLSDVVTKQNATHHHAAVTFLVDALLRTARNCYLASRLLVFAWERRRETGAKRPAEPLIALSGVTLLQPLPPEVSELLEQRTFDIGLRTPNSAVFRAFFGSLVYWAELRLALRDPASINCRYVGFHLQTSEIYLLARAHSASPGYTKEELVAMEAILTLATLMLEVALQWVHVACAQLLSENDTIKAFRRVSASIPHALAPLGSIRLHDAEFEVLSNPDVMVARDETALSQALFLGYFSVRTALTACMRDYSHEADGGSKETVTGVFLGVGLILQRLAGHLNFLLNCLAGAALYGGQKINIHSLTLPRYSLLADVMAPMLQRQSLVDFWRARDNMLEDLEITPRPGPPTQGKRVVVEMPLPSDDLPDMTPGASVNNGAGLGRMVDMAKQLQHYRETIIGEEATSSVGKRGLIRAGVGVAALRGRRRK
What is the function of this protein?
Tegument protein that can bind to various RNA transcripts.  Plays a role in the attenuation of selective viral and cellular mRNA degradation by modulating the activity of host shutoff RNase UL41/VHS.  Also plays a role in the primary envelopement of virions in the perinuclear space, probably by interacting with two nuclear egress proteins UL31 and UL34.
What are the official names of this protein?
Tegument protein UL47 homolog, GP10.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae HHV-1 UL47 family.
What are the subcellular locations of this protein?
Virion tegument. Host nucleus. Host cytoplasm. Note=Major tegument protein of the virion. Undergoes nucleocytoplasmic shuttling during infection. Localizes to the major sites of transcription in the infected cell nucleus.
Protein: CRYAA_RANTE
Sequence: QVFGEGMFDYDLFPFLTSTVSPHYRHGLLRGFMDSGISEVRSDRDRFTINLDVKHFSPDDLTVKILDDFVEIHGKHSERQDDHGYISREFHRRYRLPSNLDQSSISCSLSADGILTFSGPKMMSNLVSSHSERPIPVSREEKPTSAPSS
What is the function of this protein?
Contributes to the transparency and refractive index of the lens.  May act as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions.
What are the official names of this protein?
Alpha-crystallin A chain.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates to the nucleus during heat shock.
Protein: SYM_LEPBL
Sequence: MNSSSIQRKILVTSALPYANGPIHLGHVLEGIQTDIWVRFQKAIGNECYFFCADDTHGTPVMLAARKEKITPEQLIERVGQEHYTDLTSFGINYDNYDSTHSKANQEISKDIYLKLKEKGHISKRSIEQAYCEKDRMFLPDRFIKGTCPNCNSKNQYGDNCEVCGATYNPKDLIDSHCTLCGTPPVVKNSDHIFFKLGNFHKKTEQSNVDFDLQSWIETSEAVSESEGVKKKLKEWFDAGLQDWDISRDGPYFGFEIPSEKNKYFYVWLDAPVGYMASSKNFFEKNFPNEPNKFDSFWKDKNSEIVHFIGKDILYFHTLFWPAMLEGSGYRSPSKIHVHGFIGVNGEKMSKSRGTFIKAKTFAKFLDAEHLRFYLAAKLGPGMDDIDLSFDDFVNKVNADLVGNLINSVSRVSTTILDTLDRTLGTVSEEGLALLEEILTQPVKTGTRDDSIQNIIKTAYEQRNYAKVMREITRLGDRVNRYVNDNAPWKLIKENPEKAREIVTAVLNASRFLAIYLYPVVPKISEQIYKLLNLKGSPEFKDLDKSRILEKTKINPYEMITKRVDEKAIKVMLEENKQSEHPKKEEIPKSSNKEEGIEISIEELSKVELRVGEIVEAKPVEGADKLVNVKVDLGELGIKNVFAGIKIAYQPENLKGLKVVVVANLKPRKMKFGISEAMLLASGEGESLSLFVPHKDAKPGDRLK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VF146_ASFB7
Sequence: MGGTTDFVLSITIVLVILIIIAFIWYNFTGWSPFKYSKGNTVTFKTPDESSIAYMRFRNCIFTFTDPKGSLHSIDVTEVLNNMAKGFRDAQNPPSSFTLGGHCQAPLNAFSFVLPGVNDRATVATADDAKKWENCDATLTGLQRII
What are the official names of this protein?
Uncharacterized protein E146L, pE146L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus E146L family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein. Virion.
Protein: DEOD_STRTD
Sequence: MSIHISAKQGDIADKILLPGDPLRAKFIAENFLEDAVCFNEVRNMFGYTGTYKGERVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNENVHVRELVLAQAAATNSNIIRNDWPQYDFPQIANFNLLDKAYHIAKNFGMTTHVGNVLSSDVFYSNYFEKNIELGKWGVKAVEMEAAALYYLAAQHQVDALAIMTISDSLVNPDEDTTAEERQNTFTDMMKVGLETLIAD
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: TSGCD_HALVD
Sequence: MSFAAGLLNATVQAATVLLLAGLGELISERAGVLNLGVEGMMLVGALGGFVVTAVTGNYWLGFGVGIACGMALAAVHAFLCISLKSNQVISGVMLTLLGTGLTTFFGSGWVQESITGFPQMTFPIVGRYLVHLPLVGEAFFRSTATDYLALLAVPVVWFFLYRSNLGLEIIAVGEDPEMADTMGVPVFKFRYLAVIIGGGFAGAAGAHLSLAFSQLWVPGMTVGRGWIAVALVVFAQWRPSRMLVGAYLFGLLDALQLRSQSLSLALDPNAPLAGVLNPLVNTLMNPQIMSTYPYLTTIAVLSYAVIRTESVRLAVPSALLQSYNREMD
What is the function of this protein?
Part of an ABC transporter complex involved in glucose import (Potential).  Responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
Putative glucose ABC transporter permease protein TsgC13.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EFP_CLOTE
Sequence: MISAGDLRKGNTFELDGQVYTVVDFLHVKPGKGAAFVRTKLRNVLNGGLKETTFNPTEKFQEAVIERKEMQYLYTDGELYYFMDQQTFEQIPLNFEQVEGAIKFLKENMFAIIKFYKGEAFSVEAPNFVELQITHTDPGAKGNTATNVMKPATVETGAVVHVPLFINEGDSIRIDTRTGEYMERV
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP23_MOUSE
Sequence: MAGAPGGGELGPAAGEPLLQRPDSGQGSPEPPAHGKPQQGFLSSLFTRDQSCPLMLQKTLDTNPYVKLLLDAMKHSGCAVNRGRHFSCEVCDGNVSGGFDASTSQIVLCENNIRNQAHMGRVVTHELIHAFDHCRAHVHWFTNIRHLACSEIRAASLSGDCSLVNELFRLRFGLKQHHQIETSCVSRPAMNSQSCLGLVSA
What are the official names of this protein?
Mitochondrial inner membrane protease ATP23 homolog, XRCC6-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M76 family.
Protein: PBDGT_MYCGE
Sequence: MDKLVSILVPCYKSKPFLKRFFNSLLKQDLNQAKIIFFNDNVADETYEVLQKFKKEHNNLAIEVYCDKQNEGIGKVRDKLVNLVTTPYFYFIDPDDCFNNKNVIKEIVESIKKEDFDLGVLKSMVYLCFLKHDFIIKFLPLKGIFQGRVKLINNNNVNKLNYIKNNDQYIWNIVINTDFFRKLNLTFESRLFEDIPIWYPMFFSSQKIVFIDVIGTNYFIRNDSLSTTISAPRYLNLIQCYEKLYVNLSQNGSLASFIDPNHKIEARFWRRQMFVWFALFSFEYFKKNFSESKKILEKLFVFLEKNGVYERVFQTKNQGIYYIWVQRLKYFKHVLESKSDN
What is the function of this protein?
Processive glycosyltransferase involved in the biosynthesis of both the non-bilayer-prone beta-monoglycosyldiacylglycerol and the bilayer-forming membrane lipid beta-diglycosyldiacylglycerol.  These components contribute to regulate the properties and stability of the membrane.  Catalyzes sequentially the transfers of glucosyl or galactosyl residues from UDP-Glc or UDP-Gal to diacylglycerol (DAG) acceptor to form the corresponding beta-glycosyl-DAG (3-O-(beta-D-glycopyranosyl)-1,2-diacyl-sn-glycerol), which then acts as acceptor to give beta-diglycosyl-DAG product (3-O-(beta-D-glycopyranosyl-beta-(1->6)-D-glycopyranosyl)-1,2-diacyl-sn-glycerol).  Dioleoylglycerol (DOG) is a preferred sugar acceptor than 3-O-(beta-D-glucopyranosyl)-1,2-dioleoyl-sn-glycerol.
What are the official names of this protein?
Processive diacylglycerol beta-glycosyltransferase, Beta-diglycosyldiacylglycerol synthase, Beta-DGS, DGlyDAG synthase, Beta-monoglycosyldiacylglycerol synthase, Beta-MGS, MGlyDAG synthase, Glycosyl-beta-1,6-glycosyldiacylglycerol synthase, UDP-galactose:1,2-dioleoylglycerol 3-beta-D-galactosyltransferase, UDP-glucose:1,2-dioleoylglycerol 3-beta-D-glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Cell membrane.
Protein: RFCL_SULIM
Sequence: MIQWFLKYRPRSLKDVENQDGAKKELQEWIESWLNGKPNAKAVLLHGPPGVGKTTLAEALAHDYNLELLEMNASDSRKLQDIKSVAEKASVYGSIFGTRGKLILLDEVDGINVREDTGAIQGILELIEKTKYPLIMTANDPWNPALRELRNKTKMVGLNKLGKYPLRRLLKKICQAEKIICDDEALNYIIDTSEGDARYAINMLQGIGEGYGKVTLDLVEAMARRKERELDPFETLRDIFWARYAWQAKNAATSAQIDYDMLIRWISENIPIQYDNIEDVWRAFDALSRASIFLKRAKGGDWDLLSYAYDLMSSGVAAAEIEKKKPNWKPKWKKYQFPSYIQLLSKSKDIRDTRDEIIKKLAIHSSFNKTLNDTYPFFLIFYKKYDKRLSLNTKEKEYLNSASKS
What is the function of this protein?
Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.
What are the official names of this protein?
Replication factor C large subunit, RFC large subunit, Clamp loader large subunit.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family. RfcL subfamily.
Protein: Y2300_METMA
Sequence: MADLKITWLGHAAFLLESEKKLLIDPFISENPKSPCSPEDLNPDIIAVTHGHRDHLGDTIEIGARTGCRIISIHEVANYIKSKGVFAEGMNKGGTVEVEGIALTMTHALHSSSIDASGFSFDGGSPAGFVINIGGYSVYHSGDTGVFGDMQLIGELYKPEIALLPIGSRFTMGIKEAVKAVELIEPRIVVPMHYNTFDVIRQDPEEFRKAVEAKVDTKVIIMSPGESIQL
What are the official names of this protein?
UPF0173 metal-dependent hydrolase MM_2300.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.