PharMolix/UniProtQA huggingface dataset:
Protein: KDSA_COXBU
Sequence: MLMQIADFEIGLNNPLFLIAGPCVIESEALVMDVAGELKSITQQLDMPFIFKASFDKANRSSHLSYRGPGIEKGLTILEKVKKTLEVPIITDVHEDTPLQEVAAVVDVLQTPAFLCRQSNFIRSVAACGKPVNIKKGQFLAPWEMKQVVAKAWATGNKKIMVCERGYSFGYNNLISDMRALAILRETACPVIFDATHSVQLPGGHGTNSGGQREFVPVLARAATAAGIAGIFMETHPDPDRALSDGPNSWPLAKMQPLLETLKELDKVVKNAGFLEQSSE
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_CUPPJ
Sequence: MPRVKRGVTARARHKKVIDAAKGYRGRRNNVYRIAKQAVMRAGQYAYRDRRNKKRVFRALWIARINAATREHGMTYSVFMNGLKKASIELDRKVLSDMAIHDKPAFAAIVNQVKATVA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: HETM_NOSS1
Sequence: MSLKQNYSAADIQAWMISNLAELLGVDGDEIDATVNLESYGLDSAQAMVLVSKLEQLLGFQPSPLLLWHYPTIESLSERLAEELEEQSEEQNTDSATANHSNGTPVLDLQAEVVLDPVIHPGGAIPVDFPVTQPKKVFLTGGTGFLGAFLIRELLQQTQADVYCLVRAADAQAGKAKIQTNLEGYAIWQEEYESRIIPVVGDLAEPLLGLSSTQFQALAAEIDTIYHSGALLNYVFPYSALKAANVLGTQEVLRLACQIKVKPVHYVSSVAVFESPVYAGKVVKESDDFSHWEGIFLGYSQTKWVAEKLVKIAGDRGLPVTIHRPPLIGGDSETGIGNTHDFINLMVKGCLQMGCFPDVEYMLDMSPVDYVSKAIVHLSMQKESLGKAFHLQHPEPVSLSVLVDWVRSFGYEIKTLPYEEWQAELINNATSVDNPLYTLRPFLLERWSDEQLTIPDLYLKAKRPHISCQDTLKALAGTSIGCPPIDGKLFMTYTAYLIQTGFLTLA
What are the official names of this protein?
Polyketide synthase HetM.
Protein: ASSY_CHRVO
Sequence: MSDIKKVVLAYSGGLDTSVILKWLQDEYQCEVVTFTADIGQGEEVEPARQKAVSLGIKPENIFIEDLREEFVRDFVYPMFRANTIYEGEYLLGTSIARPLIAKRQIEIANQVGADAVSHGATGKGNDQVRFELGYYALKPDVKVIAPWREWDLLSREKLLAYAETHGIDISKKKNGGSPYSMDANLLHISYEGTVLEDPAQEPEEDMWLWSVSPENAPDQAEYVELEYRKGDIVAVNGQALSPAGVLTELNRLGNKHGIGRLDIVENRYVGMKSRGCYETPGGTIMLKAHRAIESITLDREVAHLKDELMPKYAQLIYTGYWWSPERAMLQQMIDASQATVNGWVRLKLYKGNVIVVGRESKTDSLFDPTIATFDEDGGAYNHADAAGFIRLNALRMRIAANARNKRG
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MED8_CANGA
Sequence: MSGINGALVEDIKPDYSGVPGPALDSVRMRLAQLTHSLRRIRDDLSRADLTQWYSLQSQINVTLSQLMSVTSTLQHFEDTLDSTIVYPLPKFPTTSHESLLTTLLRKKNIPEVEEWIKDAIEASGVDTNMMRDDEIEKILEKNNEDSKWALEVFAKEFEKRESNGDTADDLDVLGNALKPVKTSVRQRAQSPFQVEDVLKYMSRGEVDRGSSSQEGLSTNNEQSGDKDIIMAD
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 8, Mediator complex subunit 8.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 8 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TPS1_YARLI
Sequence: MPNVLVISNRLPVTISREEDGTYKYTMSSGGLVTALSGLKQSTTFQWFGWPGLEIPEKDKPRLINDLETMFSCVPVFMDDDLADLHYNGFSNSILWPLFHYHPGEMNFDQVAWEAYTQANRLFAKKVASIVKPGDIVWVHDYHLMLLPEMLREECENNSALDGLKIGFFLHTPFPSSEIYRILPVRKEVLTGVLSCNLIGFHTYDYARHFLSSVSRILDLETMPNGTYYKGRHVVVGAFPIGIDVNKFLEGCKRPAVQERIAQLQDKFKGIKVVVGVDRLDYIKGVPQKLHAFEVFLSEHPEWIGKVVLVQVAVPSRGLVEEYQNLRAVVNELVGRINGMFGTVEFTPIHFMHRSVDFNELIALYSISDVCFVSSTRDGMNLVSYEYVACQTEKHGSLILSEFTGAAQSLNGALIVNPWNTEDMAEALYDSLTFSPEKKAENHRKLFKYVSKYTSQHWGEAFVSELKRC
What is the function of this protein?
Synthase catalytic subunit of the trehalose synthase complex that catalyzes the production of trehalose from glucose-6-phosphate and UDP-alpha-D-glucose in a two step process (PubMed:21931609).  The disaccharide trehalose serves as a storage carbohydrate that is mobilized during spore germination (PubMed:21931609).
What are the official names of this protein?
Alpha,alpha-trehalose-phosphate synthase [UDP-forming], Trehalose-6-phosphate synthase, UDP-glucose-glucosephosphate glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 20 family.
Protein: UREG1_STRGG
Sequence: MTRTPTGVPMHLGHTHDAPAAVSADATRPDGTRRALRIGLGGPVGSGKTATVAALCRELRDRLSIAVVTNDIYTREDADFLLKNAVLPPERIQAVETGACPHTAIRDDISANLEAVEDLEDAVGPLDLILVESGGDNLTATFSKGLVDAQIFVIDVAGGDDIPRKGGPGVTTADLLVVNKTDLAPYVGSDLERMALDAKKQRGDLPVAFTSLTSAEGVGPVADWVRAQLAAWAA
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG 1.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BOPE_BURPS
Sequence: MTYNPRIGGFTHVKQASFDVHVKRGEAQPRTSFAQQIKRIFSKIGETLGQLFRHRAPDSAPGRVRLQGVRYVGSYRPTGDAKQAIRHFVDEAVKQVAHARTPEIRQDAEFGRQVYEATLCAIFSEAKDRFCMDPATRAGNVRPAFIEALGDAARATGLPGADKQGVFTPSGAGTNPLYTEIRLRADTLMGAELAARPEYRELQPYARQQAIDLVANALPAERSNTLVEFRQTVQTLEATYRRAAQDASRDEKGATNAADGA
What is the function of this protein?
Activator for both CDC42 and RAC1 by directly interacting with these Rho GTPases and acting as a guanine nucleotide exchange factor (GEF).  This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling, thus promoting bacterial entry into non-phagocytic cells.
What are the official names of this protein?
Guanine nucleotide exchange factor BopE, Effector protein BopE.
What is the protein family that this protein belongs to?
Belongs to the GEF (guanine exchange factor) SopE family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the bsa type III secretion system.
Protein: MURG_JANMA
Sequence: MKRLVIMAAGTGGHIFPGLAIAETMKARGWQVSWLGTSHGMERELVPKAGVEMDIIEFSGLRGKGLQHTITGAFKLVASFATCFSILKRRNPGIVLGMGGYVTVPGGWMAKLRGVPVVLVNADAALLLSNKTLMPVAERVLFGFPADFGPAASKALVTGNPVRQEIISLPAPAERYAQHSGPLKVLVVGGSLGAKALNDAMPLALAMLPPEQRPVVTHQSGKKNIDALRANYAQAGVDAEVLDFINDMPRRYAEADLVICRAGAITVSELTAAGVASVLVPLLVSTTTHQRDNALWMEKQNAAIHLPQSELSAQGLAELLQGMTREKCKQMAEAAYANGRRDANAAIADVLEKLVKIT
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GDIB_PIG
Sequence: MNEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESASITPLEDLYKRFNIPGAPPASMGRGRDWNVDLIPKFLMANGQLVKMLLFTEVTRYLDFKVTEGSFVYKGGKIYKVPSTEAEALASSLMGLFEKRRFRKFLVYVANFDENDPRTFEGVDPKKTAMREVYKKFDLGQDVIDFTGHALALYRTDDYLDQPCCETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPIEEIIVQNGKVIGVKSEGEIARCKQLICDPSYVKDRVEKVGQVIRVICILSHPIKNTSDANSCQIIIPQNQVNRKSDIYVCMISSAHNVAAQGKYIAIASTTVETKEPEKEIRPALELLKPIEQKFVSISDLLVPKDLGTDSQIFISRTYDATTHFETTCGDIKDIYKRMTGSEFDFEEMKRKKNDIYGED
What is the function of this protein?
GDP-dissociation inhibitor preventing the GDP to GTP exchange of most Rab proteins.  By keeping these small GTPases in their inactive GDP-bound form regulates intracellular membrane trafficking.  Negatively regulates protein transport to the cilium and ciliogenesis through the inhibition of RAB8A.
What are the official names of this protein?
Rab GDP dissociation inhibitor beta, Rab GDI beta, Guanosine diphosphate dissociation inhibitor 2, GDI-2.
What is the protein family that this protein belongs to?
Belongs to the Rab GDI family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: NRDI_SHIFL
Sequence: MSQLVYFSSSSENTQRFIERLGLPAVRIPLNERERIQVDEPYILIVPSYGGGGTAGAVPRQVIRFLNDEHNRALLRGVIASGNRNFGEAYGRAGDVIARKCGVPWLYRFELMGTQSDIENVRKGVTEFWQRQPQNA
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: ENO_AERS4
Sequence: MSKIVKVIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVLKALEAVNGPIAQALLGKDAKDQAAIDQIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYAHIAELNGTAGVYSMPLPMMNIINGGEHADNNVDIQEFMIQPVGAKTLKEAVRMGAEVFHNLAKVLKSKGYNTAVGDEGGFAPNLKSNAEALEVIAEAVAAAGYVLGKDITLAMDCAASEFYDAEKKEYNLKGEGRIFTSNEFSDYLADLTTKFPIVSIEDGLDESDWDGFAYQTKELGKKIQIVGDDLFVTNTKILKRGIDNGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGAKAPFNGLKEVKGQA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RNS3_KITAU
Sequence: MRIPPRLVALAGAAAVAATLIAGPVAAAAPASHAVAASSAASASVKAVGRVCYSALPSQAHDTLDLIDEGGPFPYSQDGVVFQNREGLLPAHSTGYYHEYTVITPGSPTRGARRIITGQQWQEDYYTADHYASFRRVDFAC
What are the official names of this protein?
Guanyl-specific ribonuclease Sa3, RNase Sa3.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease N1/T1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS5_AYWBP
Sequence: MSQIRLTFLKEKNKMKAIKKEFNKKAALLEEKVVKINRITKVVKGGARFRFSALVVVGDKKGQIGFATAKAKEIVEAIKKALEKAKKQLVRIPIVGTTIPHDTIGRFGASKFFLKPASKGTGIVAGGKAARTILELVGINDVLTKTFGSRTSINVIRAVMDGLQSLRTKEEVAKLRGINLAKKEQ
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: Y608_HAEIN
Sequence: MGEMASLRSHKNGIIFILDIVLFFVLLNVLPFEPKANSGLALLAFIAVLWLSEALHVTITALLVPLLAVALGLVSTKQALVGFADPTIFLFFGGFSLATALHIQKLDKLIANKIMALARGNLFIAVIYLFLITAFLSMWMSNTATAAMMLPLAMGILSQLDREKDHNTYVFVLLGIAYSASIGGMGTLVGSPPNAIVASNLNLTFSDWLWYGLPIMIILLPLMIGILYIIFKPKLHLNFEQTFENIEMNPMRILTFIIFPVIALTWIFSGKINPFISGLLGLQKNIASFDSIVALLAAIVICSTGVASWKQIQSNTDWGVLMLFGGGLTLSAVLKDSGASKILADSIVFMIDGQHFYLIGLLVAAFIIFLTEFTSNTASAALLVPIFISIAQSLGMPEIGLALIIGIGASCAFMLPVATPPNAIVFGSGQVKQSEMVKVGFLLNLVCVVVIATMGYMFWLK
What are the official names of this protein?
Uncharacterized transporter HI_0608.
What is the protein family that this protein belongs to?
Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LGT_SOLM1
Sequence: MFVHPQFDPVAVSLGPLSIRWYGLMYLIGFAAAWLLGRYRASRPGSGWTPLQVDDLVTYMVLGVVVGGRLGYMLFYDLPAFLANPLSLVQVWQGGMSFHGGFLGVLAVVWFFGRKTGKGFWGVADFTAPLAPFGLFAGRIGNFINGELWGKATDLPWGVVFPDPRAGGVPRHPSQLYEALLEGAALFLIVWLYSSKKRQSGAVSGVFCVCYGLFRFAVELVRLPDPQLGYLAFGWLTMGQLLSLPVIVFGLWLLARRAPDQNASQ
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y9KD_BPBF2
Sequence: MKNVITAPKIGQSVFIPFVTKTDELTGKTERIKGAALIPFDTIDAVYAENERSNNGKTVFSVRVKSGDVVKVVQRNEKWEAVL
What are the official names of this protein?
Uncharacterized 9.2 kDa protein.
Protein: MLC1_DROME
Sequence: MADVPKREVENVEFVFEVMGSPGEGIDAVDLGDALRALNLNPTLALIEKLGGTKKRNEKKIKLDEFLPIYSQVKKEKEQGCYEDFIECLKLYDKEENGTMLLAELQHALLALGESLDDEQVETLFADCMDPEDDEGFIPYSQFVQRLMSDPVVFD
What are the official names of this protein?
Myosin light chain alkali.
Protein: OL958_MOUSE
Sequence: MEIKNCSVVTEFILLGIPHTEGFETLLFVLFLPFYACTLVGNVSILVAVISSTRLHTPMYFFLGNLSVFDMGFSSVTCPKMLFYLMGLSRLISYQDCVSQLFFFHFLGSIECFLYTVMAYDRFAAICHPLRYSVIMNSKICVALAVGTWLLGCFHSSVLTSLTFTLPYCGPNEVDHFFCDIPAILPLASADTSLAQRVSFTNVGLVSLVCFLLILLSYTRITISILSIQSTEGRQRAFSTCSAHLIAILCAYGPIITIYLQPTPNPMLGTVVQILMNLVGPMLNPLIYTLRNKEVKIALKKILHGKGSVSEG
What is the function of this protein?
Potential odorant receptor.
What are the official names of this protein?
Olfactory receptor 958, Olfactory receptor 224-9.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UBP14_CAEEL
Sequence: MPIVNVKWQKEKYVVEVDTSAPPMVFKAQLFALTQVVPERQKVVIMGRTLGDDDWEGITIKENMTIMMMGSVGEIPKPPTVLEKKQANRDKQAEEISALYPCGLANLGNTCYFNSCVQMLKEVNELVLKPAEEMRIREHNDRLCHNLATLFNSLRDKDRALRSKGEPIKPFAAILTLSDSFPQFEKFKQQDANECLVSIMSNVTRIYGLSGWNIESLFRIQTETTMKCLESDEVSEKKVERNNQLTCYVNQDVRFLQTGIKAGFEEEMTRNSEELNRDAKWQKNTQISRLPKYLTVNINRFFYKESTKTNAKILKSVQFPMQLDTYDLCSQELKDKLVARRADIKLEEDAKLERELRKKVLDKEQGDKIFDDGVALPTAFEDDAGSNNSGFYDLKGIITHKGRSSQDGHYVAWMRSSEDGKWRLFDDEHVTVVDEEAILKTSGGGDWHSAYVLLYEARVIKQFPELPPAPVPTEVAADTAEPMEVSEKQ
What is the function of this protein?
Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins.  Ensures the regeneration of ubiquitin at the proteasome (By similarity).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 14, Deubiquitinating enzyme 14, Ubiquitin thioesterase 14, Ubiquitin-specific-processing protease 14.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. USP14/UBP6 subfamily.
Protein: UBIE_VIBVY
Sequence: MTDISVQSNTALESSETTHFGFTTVAKEEKVAKVAQVFHSVAAKYDIMNDLMSGGIHRLWKRFTIDCSGARPGQRVLDLGGGTGDLTAKFSRIVGEKGHVILADINNSMLNVGRDKLRDSGIVGNVHYVQANAEELPFPDDYFDIITISFCLRNVTDKDKALRSMFRVLKPGGRLLVLEFSKPVFDPLSKVYDAYSFHLLPKMGELVANDADSYRYLAESIRMHPDQETLKGMMQEAGFENTSYYNLTGGIVALHRGYKF
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: ASF1A_BOVIN
Sequence: MAKVQVNNVVVLDNPSPFYNPFQFEITFECIEDLSEDLEWKIIYVGSAESEEYDQVLDSVLVGPVPAGRHMFVFQADAPNPGLIPDADAVGVTVVLITCTYRGQEFIRVGYYVNNEYTETELRENPPVKPDFSKLQRNILASNPRVTRFHINWEDNTEKLEDAESSNPNLPSLLSTDALPSASKGWSTSENSLNVMLESHMDCM
What is the function of this protein?
Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.  Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly.  Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.
What are the official names of this protein?
Histone chaperone ASF1A, Anti-silencing function protein 1 homolog A.
What is the protein family that this protein belongs to?
Belongs to the ASF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GUAC_SALEP
Sequence: MRIEEDLKLGFKDVLIRPKRSTLKSRSDVELERQFTFKHSGQTWSGVPIIAANMDTVGTFEMAQALAGFDILTAVHKHYTVEEWAAFINTASADVLKHVMVSTGTSDADFEKTVQILALNPALNFVCIDVANGYSEHFVQFVAKAREAWPTKTICAGNVVTGEMCEELILSGADIVKVGIGPGSVCTTRVKTGVGYPQLSAVIECADAAHGLGGMIVSDGGCTMPGDVAKAFGGGADFVMLGGMLAGHEESGGSVVEENGEKFMLFYGMSSESAMNRHVGGVAKYRAAEGKTVKLPLRGPVGNTARDILGGLRSACTYVGASRLKELTKRTTFIRVQEQENRIFNSL
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
Protein: ZHX2_MOUSE
Sequence: MASKRKSTTPCMVRTSQVLEQDMLEEADRAKDKGAGMPQSDVTKDSWAAEPEHSSKETEVVEVKSMGENLSKKLQGGYECKYCPYSTQNLNEFTEHVDMQHPNVILNPLYVCAECNFTTKKYDSLSDHNSKFHPGETNFKLKLIKRNNQTVLEQSIEATNHVVPITASGPGSSDNDPGVSVGKTPMTKTGKLKADAKKVPKKPDEAAPENHMEGTARLVTDTAEILARLGSVELLQDSLGHVMPSVQLPPNINLVPKVPVPLNTTKYNSALDTNATMINSFNKFPYPTQAELSWLTAASKHPEEHIRIWFATQRLKHGISWSPEEVEEARKKMFNGTIQSVPPTITVLPAQLTPTKVSQPILQTALPCQILGQPSLVLTQVTSGSTTVSCSPITLAVAGVTNHGQKRPLVTPQAAPEPKRPHIAQVPEPPPKVANTPLTPASDRKKTKLQIAHLKASFLQSQFPDDAEVYRLIEVTGLARSEIKKWFSDHRYRCQRGIVHITSESLAKDQMAITGTRHGRTYHVYPDFAPQKFKEKSQGQLKTLEDSFLKSSFPTQAEVERLRVETKLSRREIDSWFSERRKLRDSMEQAVLDSMGSGKKGSDAVAPNGALSRLDQLSGAQLAGSLPSPSSAIVQNQEQVHLLRSTFARTQWPTPQEYDQLAAKTGLVRTEIVRWFKENRCLLKTGTLSWLEQYQRHHMSDDRGRDAVSRKVAKQVAESPKNGSEAAHQYAKDPKALSEEDSEKLVPRMKVGGDPTKDCLAGKPSEATSDRSEGSRDGQGSEENEESGIVDFVEVTVGEEDAISEKWGSWSRRVAEGTVERADSDSDSTPAEAGQA
What is the function of this protein?
Acts as a transcriptional repressor (PubMed:19515908).  Represses the promoter activity of the CDC25C gene stimulated by NFYA (By similarity).  May play a role in retinal development where it regulates the composition of bipolar cell populations, by promoting differentiation of bipolar OFF-type cells (PubMed:30146259).  In the brain, may promote maintenance and suppress differentiation of neural progenitor cells in the developing cortex (PubMed:19515908).
What are the official names of this protein?
Zinc fingers and homeoboxes protein 2, Alpha-fetoprotein regulator 1, AFP regulator 1, Regulator of AFP, Zinc finger and homeodomain protein 2.
What is the protein family that this protein belongs to?
Belongs to the ZHX family.
What are the subcellular locations of this protein?
Nucleus. Note=Colocalizes with EFNB1 intracellular domain in the nucleus.
Protein: RLMN_THEVB
Sequence: MVLLGRSAAELKAWVEAQGQPGYRGQQLHQWLYRKGARSLQEITVFPKQWRAALADVEIGRSEIRYRHDAQDGTVKLLLALADGETIETVGIPSSDRLTVCVSSQVGCPMACDFCATGKGGYRRNLACHEILDQVLTIQSEMGRRVSHVVFMGMGEPLLNLPAVLQAITCLNRDIGIGQRHITISTVGIPQQIQRLAQHQLQTTLAVSLHAPNQALREQLIPSAKHYPLSQLIADCRAYVQQTGRRITFEYTVLAGVNDRPQHAEELAQLLRGFQSHVNLIPYNPIAEAAYQRPTDQHLRQFLSQLQALGVTASIRRSRGLDRQAACGQLRQAQLIA
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SHEP_DROER
Sequence: MHPRYSPAPPPQQQQQMGGPPHQQQGGGGGGGGSMRGPSNAQQLPPQIPRSQNYSNGSSSSAAAAPPTSRSAFPGAPLTASAVALKGALPQRPPAMTSPAAAAAGAALAAGAPYRGAASWTPQGYAPAAAAAAAAVAQQAAYRYTAPLPQPAYAAYTPHTATTPATTTYGQRVPTAASPSNTNSSSSSNTGSQSGTLSTSLSNTTNTNTNMGPNGTVQNQNQQGGEQLSKTNLYIRGLQQGTTDKDLVNMCAQYGTIISTKAILDKTTNKCKGYGFVDFEQPAFAECAVKGLQGKGVQAQMAKQQEQDPTNLYIANLPPHFKETDLEAMLSKYGQVVSTRILRDQQMNSKGVGFARMESREKCEQIIQMFNGNTIPGAKDPLLVKFADGGPKKKNLFKTPDPNARAWRDVSAEGIPVAYDPTMQQNGVSVNVGTPIGVPYSRFSAPQVGGYPVAGSQWIPGYMMTQPITQVDDQTSYSPQYMQMAAAPQLGVTSYKPEAVNQVQPRGISMMVSGDTGVPYGTMMPQLATLQIGNSYISPTYPYYAPPPTIIPTMPMTDSEQASTAASPDEAYTQYPHQAAPK
What is the function of this protein?
Has a role in the perception of gravity.
What are the official names of this protein?
Protein alan shepard.
Protein: RL332_STRP1
Sequence: MAQKKASLACVECGSRNYSIGVSSTPKPTRLEVNKFCKYCKTYTLHKETR
What are the official names of this protein?
50S ribosomal protein L33 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: CBF5_CHATD
Sequence: MSGSAAIMKAPAKSEFIIKPENTKAEVDTSNWPGLLKNYDKMLIRTSHFTPIPDHGSAPWSRDIKSYVSSGVINLDKPSNPSSHEVVAWIKRILRVDKTGHSGTLDPKVTGCLIVCIDRATRLVKAQQGAGKEYVCCIRFHDTVPGGEPAFAKALETLTGALFQRPPLISAVKRQLRIRTIHKSRLLEFDNERHLGVFWVSCEAGTYIRTLCVHLGLLLGVGAHMQELRRVRSGVMSEDDGSLVTLHDVLDAQWQYDNNGDEALLRKVIQPLETLLCTYKRLVVKDTAVNAVCYGAKLMIPGLLRYDQGIEQGEEVVLMTTKGEAIAIAIAQMGAVELATCDHGCVAKVKRCIMERDLYPRRWGMGPVASEKKKLKASGLLDKYGRPNEKTPASWLQSYKDYNVSSSEAPALPAPAGADAAAAPSTPALPAPEEKNESEEKSADASDSKKRKKDETAEEKAERKRLKKEKKEKKEKKKSDKDE
What is the function of this protein?
Catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA.  This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1.  Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs and play a central role in ribosomal RNA processing.  The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs.  Catalyzes pseudouridylation at position 93 in U2 snRNA.  Also catalyzes pseudouridylation of mRNAs; H/ACA-type snoRNAs probably guide pseudouridylation of mRNAs.
What are the official names of this protein?
H/ACA ribonucleoprotein complex subunit CBF5, Centromere-binding factor 5, Centromere/microtubule-binding protein CBF5, H/ACA snoRNP protein CBF5, Small nucleolar RNP protein CBF5.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.