PharMolix/UniProtQA huggingface dataset:
Protein: TBC8B_DANRE
Sequence: MWLKPEEVLLKNALKLWVTEKSNDYFVLQRRRGYGEDSGGLTGLLVGTLDTVLDSTAKVAPFRILHQTPDSQVYWTIACGASLEEISQHWDWLQQNIVRTLSVFDSGEDITSFVQGKIRGLIAEEGTSAGDEEDPERFREAVLRFERLFGLPQREKLVTYFSCSYWRGRVPNQGWIYLSTNFLCFYSYMLGNEVKLVYPWDEVSRLERTSSVLLAESIRVRVRGEDHFFSMLLRLQQTYLIMQQLADYAIVRFFDKETFHAEHPLANPLHITQRALEIHARNQSFRSFFRLPQEENLCEVYESFLWVPFSHVNTLGKICVSENYLCFASQDGSQCHLIIPLWEVFSVELPDRSSRALTVCLRGKRALRFSEVRDFERLAATIRRKCGTLGSPQHCITNPDEEGVMVGQSQAVSTEALMNVFHPHDAENLDPKMLKERMKEQSWQIHFAEYGRGTGMFCTKKTRDLIVRGVPETLRGELWMLFSGAVHDMISHPGYYGRLLEDCMGSSSLACDEIERDLHRSLPEHPAFQSDTGISALRRVLTAYAHRNPKIGYCQAMNILTSVLLLYAKEEEAFWLLVAVCERMLPDYFNRRIIGALVDQAVFEELIREHLTQLTEHMTDLSFFSSVSLSWFLTLFISVLPIESAVNVVDCFFYDGIKAILQLGLAVLDYNMDNLLCCNDDAEAVTVLNRFFDSVTNKDSPLPATVQQASATANDKSIQKVDISDLIKEAYEKYGDIRTEEVENMRKRNKLYVIQTLEDTTKQNVLRVVAQDVKFSASQLDELYLLFKNHDPSLPYLDQYQLDQSQFSSLFNLLQPWTTHTHSRSLARSAFHLLDENGDGLVNFKEFICGLDILYNRSFTEKLKLLFKLHLQPDSAEDGVIRKCPERGRAKVDLQEYLKQWQEDLQRREENIKDLPRINQVQFISLTKTLYSVFHGDEEEESLYRAVARVTSLLLRMEEVGRKLQDSSPQKTPQTTPTSTSQPESSPTKPTSPESETPAESRSTHDQPESPVSQHETAPSHSDITPNSTSHPSTPTSSPTETSSPVLDTPTDTPSSPCTVRDGDWSFSFEQILASLLNEPSVVRFFERVVNTDTLITRARKNQLKDAH
What is the function of this protein?
Involved in vesicular recycling, probably as a GTPase-activating protein for Rab family protein(s).
What are the official names of this protein?
TBC1 domain family member 8B.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: MUTS2_BACSU
Sequence: MQQKVLSALEFHKVKEQVIGHAASSLGKEMLLELKPSASIDEIKKQLDEVDEASDIIRLRGQAPFGGLVDIRGALRRAEIGSVLSPSEFTEISGLLYAVKQMKHFITQMAEDGVDIPLIHQHAEQLITLSDLERDINSCIDDHGEVLDHASETLRGIRTQLRTLESRVRDRLESMLRSSSASKMLSDTIVTIRNDRFVIPVKQEYRSSYGGIVHDTSSSGATLFIEPQAIVDMNNSLQQAKVKEKQEIERILRVLTEKTAEYTEELFLDLQVLQTLDFIFAKARYAKAVKATKPIMNDTGFIRLKKARHPLLPPDQVVANDIELGRDFSTIVITGPNTGGKTVTLKTLGLLTLMAQSGLHIPADEGSEAAVFEHVFADIGDEQSIEQSLSTFSSHMVNIVGILEQVNENSLVLFDELGAGTDPQEGAALAMSILDDVHRTNARVLATTHYPELKAYGYNREGVMNASVEFDIETLSPTYKLLIGVPGRSNAFEISKRLGLPDHIIGQAKSEMTAEHNEVDTMIASLEQSKKRAEEELSETESIRKEAEKLHKELQQQIIELNSKKDKMLEEAEQQAAEKVKAAMKEAEDIIHELRTIKEEHKSFKDHELINAKKRLEGAMPAFEKSKKPEKPKTQKRDFKPGDEVKVLTFGQKGTLLEKTGGNEWNVQIGILKMKVKEKDLEFIKSAPEPKKEKMITAVKGKDYHVSLELDLRGERYENALSRVEKYLDDAVLAGYPRVSIIHGKGTGALRKGVQDLLKNHRSVKSSRFGEAGEGGSGVTVVELK
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: RL28_PSEPF
Sequence: MSRVCQVTGKGPVTGNNISHANNKTRRRFLPNLQHHRFWVEEEKRFVRLRVSAKGMRIIDKRGISVVLAELRRDGKV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: NNRD_DROPS
Sequence: MSAIKEIPVNLPKLLTLFKTIVPKLTNDKYKGQYGRIGVIGGSLEYTGAPFFAAISSMKVGADLSHVFCQANAAPVIKSYSPDLIVHPVLDCLDAVDKIQPWLERLHVIVIGPGLGREPLILQTVTNVLKLCTKLQKPIVIDADGLFILNDNIDLVSGQRNIILTPNAMEFRRLFGEDVNDVRQKMSCLGDGVVVLEKGVNDKIHIPHTNEVYSMPTGGSGRRCGGQGDLLSGSLATFFYWSLQSNQPNPAYIAACASSYLVKRANSTAFKKFGRSLLASDMINEISAVFRSDFEDAETG
What is the function of this protein?
Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP.  Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
What are the official names of this protein?
ATP-dependent (S)-NAD(P)H-hydrate dehydratase, ATP-dependent NAD(P)HX dehydratase.
What is the protein family that this protein belongs to?
Belongs to the NnrD/CARKD family.
Protein: SODM1_ARATH
Sequence: MAIRCVASRKTLAGLKETSSRLLRIRGIQTFTLPDLPYDYGALEPAISGEIMQIHHQKHHQAYVTNYNNALEQLDQAVNKGDASTVVKLQSAIKFNGGGHVNHSIFWKNLAPSSEGGGEPPKGSLGSAIDAHFGSLEGLVKKMSAEGAAVQGSGWVWLGLDKELKKLVVDTTANQDPLVTKGGSLVPLVGIDVWEHAYYLQYKNVRPEYLKNVWKVINWKYASEVYEKENN
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn] 1, mitochondrial, Protein MANGANESE SUPEROXIDE DISMUTASE 1, AtMSD1, Protein MATERNAL EFFECT EMBRYO ARREST 33.
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RL35_ECO8A
Sequence: MPKIKTVRGAAKRFKKTGKGGFKHKHANLRHILTKKATKRKRHLRPKAMVSKGDLGLVIACLPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: AMPC_CITFR
Sequence: MMKKSICCALLLTASFSTFAAAKTEQQIADIVNRTITPLMQEQAIPGMAVAIIYEGKPYYFTWGKADIANNHPVTQQTLFELGSVSKTFNGVLGGDRIARGEIKLSDPVTKYWPELTGKQWRGISLLHLATYTAGGLPLQIPGDVTDKAELLRFYQNWQPQWTPGAKRLYANSSIGLFGALAVKSSGMSYEEAMTRRVLQPLKLAHTWITVPQSEQKNYAWGYLEGKPVHVSPGQLDAEAYGVKSSVIDMARWVQANMDASHVQEKTLQQGIELAQSRYWRIGDMYQGLGWEMLNWPLKADSIINGSDSKVALAALPAVEVNPPAPAVKASWVHKTGSTGGFGSYVAFVPEKNLGIVMLANKSYPNPARVEAAWRILEKLQ
What is the function of this protein?
This protein is a serine beta-lactamase with a substrate specificity for cephalosporins.
What are the official names of this protein?
Beta-lactamase, Cephalosporinase.
What is the protein family that this protein belongs to?
Belongs to the class-C beta-lactamase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: KAPS_SCHPO
Sequence: MATNITFHPGSVTKEERIKFVGHPGMTIWMTGLSASGKSTIACALEQYLLQRGVTTYRLDGDNVRFGLNSDLGFSEQDRNENIRRIGHVAKLFADACVVAVTSFISPYRKDRDQAREFHKKDGLPFIEVYVECPVEVAEQRDPKGLYKRARAGEIKEFTGISAPYEAPISPEIVVSSHTQSIEECVEKIVNYLLEKDLITLK
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.  Required for methionine synthesis.
What are the official names of this protein?
Adenylyl-sulfate kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase, APS kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CHSY_DIACA
Sequence: MASIEEIRQAPRADGPATILAIGTATPPNAIYQADYPDYYFRVTKSEHMTELKEKFRRMCDKSMIKKRYMYLTEEILKENPNLCEYMGSSLDTRQDMVVSEVPRLGKEAAVKAIKEWGQPKSKITHVIMCTTSGVDMPGADYQLTKLLGLRPSVRRFMLYQQGCFAGGTVLRLAKDLAENNKDARVLVVCSEITAICFRGPTEAALDSMVGQALFGDGAGALIVGSDPDLSIERPLFQMAWAGQTLLPDSDGAIDGHLREVGLTFHLLKDVPGIISKNITNALEDAFSPIGVSDWNNLFWIAHPGGPAILDQVEAKLGLKEEKLAATRNVLSDFGNMSSACVLFILDEMRKKSLRDGATTTGEGLDWGVLFGFGPSLTVETVVLHSVPLNC
What is the function of this protein?
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
What are the official names of this protein?
Chalcone synthase, Naringenin-chalcone synthase.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: IMCL2_ORYSJ
Sequence: MRPVSSAEEVGALLSRSDSSGRRRRSSPVQSASPRPAGCGCGGPRRQSSFRDDVGHAASETYLVTRLTFSLLQYLGLGYRWMSQLLALTIYAILLMPGFLQVGYYYFFSSQVRRSIVYGEQPRNRLDLYIPKDINRPCPVVAFVTGGAWIIGYKAWGSLLGRRLAERGIIVACIDYRNFPQGTIGDMVSDASQGISYVCNNIASYGGDPNRIYLVGQSAGAHIAACALIEQAVKESSGQSISWSVTQIKAYFGLSGGYNMHSLVDHFHERGLNRSIFFSIMEGEESLSRYSPEIVVKQSSSQTIALLPPIVLMHGTEDYSIPSSARFLLMPSADVHLR
What is the function of this protein?
Catalyzes the demethylation of isoprenylcysteine methylesters.
What are the official names of this protein?
Probable isoprenylcysteine alpha-carbonyl methylesterase ICMEL2, Isoprenylcysteine methylesterase-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Isoprenylcysteine methylesterase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: PHLA2_XENTR
Sequence: MSVCGGAPPPAILKEGDLEKRSDSFLQLWKKRRCVLTADGLHLYSDARKRGKAKVLRFDSLAKLECVEWKGERVYFTLVTLGGQEIDFRCRERSRWNAEITLALVGFQNRRAVRELRERKEHQARDNGERLRSWGP
What is the function of this protein?
Plays a role in regulating placenta growth.  May act via its PH domain that competes with other PH domain-containing proteins, thereby preventing their binding to membrane lipids (By similarity).
What are the official names of this protein?
Pleckstrin homology-like domain family A member 2, Imprinted in placenta and liver protein.
What is the protein family that this protein belongs to?
Belongs to the PHLDA2 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: AHPD_RHOP5
Sequence: MTIEVLKERIPDFAKDVRLNLSSMASDETLGEQTKYGLLVATAIATRNVEVIAAIEAEAAGKLSPAALGAAKSAAAIMAMNNVYYRFVHLASNKDYATMPARLRMNVIANPGVDKADFELWSLAVSAINGCGMCIDSHEKVLLQAGVSTAAIQTAVRFAAIMQSVAVSIEAGAASLAVAAE
What is the function of this protein?
Antioxidant protein with alkyl hydroperoxidase activity.  Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
What are the official names of this protein?
Alkyl hydroperoxide reductase AhpD, Alkylhydroperoxidase AhpD.
What is the protein family that this protein belongs to?
Belongs to the AhpD family.
Protein: MACB_SALCH
Sequence: MTALLELCNVSRSYPSGEEQVAVLKDISLQIHAGEMVAIVGVSGSGKSTLMNILGCLDKPTSGTYRVAGRDVSTLDPDALAQLRREHFGFIFQRYHLLSHLTAAQNVEIPAVYAGIERKKRQTRARELLLRLGLSDRVDYPPSQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHSGEEVMAILRQLRDRGHTVIIVTHDPLIAAQAERIIEIHDGKIVHNPPAQEKKREQGVDAAVVNTAPGWRQFASSFREALSMAWLAMAANKMRTLLTMLGIIIGIASVVSIVVVGDAAKQMVLADIRAMGTNTIDIHPGKDFGDDNPQYRQALKYDDLVAIQKQPWVNSATPSVSKSLRLRYGNIDIAVNANGVSGDYFNVYGMSFREGNTFNAVQQQDRAQVVVLDANTRRQLFPNKANVVGEVVLAGNMPVIVIGVAEEKPSMYGNSNLLQVWLPYSTMSDRIMGQSWLNSITVRVKDGVDSDQAEQQLTRLLTLRHGKKDFFTWNMDSVLKTAEKTTYTLQLFLTLVAVISLVVGGIGVMNIMLVSVTERTREIGIRMAVGARASDVLQQFLIEAVLVCLVGGALGISLSMFIAFMLQLFLPGWEIGFSLTALASAFLCSTFTGILFGWLPARNAARLDPVDALARE
What is the function of this protein?
Part of the tripartite efflux system MacAB-TolC.  MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation.  Confers resistance against macrolides.
What are the official names of this protein?
Macrolide export ATP-binding/permease protein MacB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YCGA_BACSU
Sequence: MSMPAAETQPKKKRMTFKMPDAYVLLFMIAFICAIASYIVPAGEFDRVTKGDVTTAVPGSYHSIEQSPVRLISFFTSLQDGMVGSAPIIFLILFTGGTIAILEKTGAINGLIYNVISKFRTKQLLFICIVGALFSILGTTGIVVNSVIGFIPIGLIVARSLKWDAVAGAAVIYIGCYAGFNSTILSPSPLGLSQSIAELPLFSGIGLRVVIYICFLLSSIIYIYLYTRKLKKSKDASVLGTDWFPAAGMGEAGKEEDQSVPFTVRHKLILAVAGLSLVGFLYGALKLGWSDSQMAATFIFISVLAGLIGGLAANDIAKTFITGCQSLVYGALIVGMARSISVILENGKLLDTVVNALASLLDGFSPIAGAIGMYIASALLHFLISSGSGEAVVFIPILAPLADLMGITRQVAVEAVMLGEGVVNCVNPTSGVLMAVLAASGIPYVKWLRFMVPLALIWFLIGLVFIVIGVMINWGPF
What are the official names of this protein?
Uncharacterized protein YcgA.
What is the protein family that this protein belongs to?
To E.coli YfcC and H.influenzae HI_0594.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RRF_MYCA1
Sequence: MIDEALFDAEEKMEKAVAVARDDLSTIRTGRANPGMFSRIVIDYYGAATPITQLASINVPEARLVVIKPYEASQVGAIETAIRNSDLGVNPTNDGTLIRVAVPQLTEERRRELVKQAKSKGEDAKVSVRNIRRKAMEELHRIRKDGEAGEDEVGRAEKDLDKTTHQYITQIDELVKHKEGELLEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_AERS4
Sequence: MQQLEEVVGQAKAEIEGVNDVATLDEIRVKYLGKKGFFTEQMKTLGALSAEERPAAGAVINQAKQQVQDALNARRDALVEQELNQKLAAETIDVSLPGRRIENGGLHPVTRTIERIERLFGEMGFKVERGPEIEDGFHNFDALNIPAHHPARTDHDTFYFNPDLMLRTHTSGVQIRTMEHQQPPIRIIAPGRVYRNDYDMTHTPMFHQVEGLLVDEHASFTELKGILHDFLRNYFEEDLTIRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRSVGIDPEKYSGFAFGMGVERLTMLRYGVNDLRAFFENDLRFLKQFK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRM82_SCHPO
Sequence: MSEQRVFKHPCQFLTWNSKHNYIVCCSGPYLLGFSCSTGEKIFEHCYRDNINEKHREAAAYGEAIRQVAFSKDYSRMATVSEDKCLRLWDSTQPDKIELLYQKNIPKRCADLCFAGSNEIVFGDKFGDVYCVDENWFTTSEVTEEKKSNVVEGKQEPVNNDTLKDSKLQKLEPIMGHVSILTQLIVAQNPQNSKEEIIITSDKDEHIRISRFPNAFVIEGFCLGHEDFVSRMSLYDNRTLISGGGDNHVFVWDLENFKCLDAFDLRSAFSTYLSLNQPMVVSVILPIFKRQLVAFACEGMAGLIFAKVTPEKRLLFHSALKLSGPVLDAVLLDTDTDQILISLDSSFTFGACFECVKFDEGNAAVLTKPDVIKRIESDGLISTEKPFCPLAQIHTLRKNHSKFIRSVETGTSSPSVESKDN
What is the function of this protein?
Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.  In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit trm82, Transfer RNA methyltransferase 82.
What is the protein family that this protein belongs to?
Belongs to the WD repeat TRM82 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DPB4_CANGA
Sequence: MPPKGWRKDAQGNYPTTSYMKEQENVTMQDLLFPRSVIMALAKEVPEMQQQQVQVQAAEKGEPVEKTPAKKLVVTKDASMALQHSATVFVNHLLMYARELAKEQDRRSCNVDDILNALEHMGHPGLKPLVANRLDDYQEALEWKKQLKAQLQILNGEAEEEPNELGTYDHDNETDDEEIRDEPEKKLKVEP
What is the function of this protein?
As accessory component of the DNA polymerase epsilon (DNA polymerase II) participates in chromosomal DNA replication.
What are the official names of this protein?
DNA polymerase epsilon subunit D, DNA polymerase II subunit D.
What are the subcellular locations of this protein?
Nucleus.
Protein: ODO1_BACSU
Sequence: MFQNSMKQRMNWEDFYGPNLGYALELYDQYTQDPNSIDPDLKEMFDELGAPPSDIKEASGTKEKGRVTADLIQKIASAVRLAEDIRTYGHLNASVNPLRKDEKKSELFPLSDYGLTEEEIKAIPASVICKDAPKNISNGLEAIQYLRNTYKRTISFEFDHVHDFKEREWLTRKIESGELFQKNSAEKLSAVLERLTEVEGFEQFLHRTFVGQKRFSIEGLDALVPVLDDIIAQSVKSGTTSVNIGMAHRGRLNVLAHVLGKPYEIIFSEFQHAPNKDLVPSEGSIGISYGWTGDVKYHLGANRELQDAETKSARITLANNPSHLEFINPIVEGSTRAAQETRTQSGYPVQDETKSLAILIHGDAAFPGEGIVAETLNLSSLKGYQVGGAIHIIANNMIGFTTESAESRSTKYASDLAKGYEIPIVHVNADDPEACLSAVKFAVEYRKTFNKDFLIDLIGYRRYGHNEMDEPSTTQPMLYDAVRKHPTVKQIFAEKLVKEGVVTEEVVQNIEKSVTKRIEDAYQKVPSKKEHTACEIELPEPVSNGFPDVDTSIDFDVLRKLNGELINWPESFNVFGKLKRILERRAKAFDDDRKVEWSLAESLAFASILKDGTPIRLTGQDSERGTFAQRNLVLHDSETGKEFVPLHHLSDCSTSFAVHNSPLSEGSVLGFEYGYNVHSPETLVLWEAQYGDFANAAQVYFDQFISAGRAKWGQKSGLVMLLPHGYEGQGPEHSSGRIERFLQLAAENNWTVANLTSAAQYFHILRRQAKMLLREEIRPLVIMTPKSLLRNPNTVSEVQELSESRFQPVYEQSGLSHDYEKVTRLVLSSGKVSIDISDHFNKLEDGKEWLHIARIEQLYPFPAKGVKELFAKLPNLKEIVWVQEEPQNMGAWGYISPYLTEIAPEGVSVQYIGRRRRSSPAEGDPTVHKKEQERIVSDSLTRKN
What is the function of this protein?
E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
What are the official names of this protein?
2-oxoglutarate dehydrogenase E1 component, Alpha-ketoglutarate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the alpha-ketoglutarate dehydrogenase family.
Protein: MNHC2_STAAU
Sequence: MNLILLLVIGFLVFIGTYMILSINLIRIVIGISIYTHAGNLIIMSMGTYGSSRSEPLITGGNQLFVDPLLQAIVLTAIVIGFGMTAFLLVLVYRTYKVTKEDEIEGLRGEDDAK
What is the function of this protein?
Expression of the mnh2 operon in E. coli is not able to catalyze Na(+)Li(+)/H(+) antiport.  It does however confer higher growth rates than the control strain at up to pH 9. 5.  The operon may encode an NADH-ubiquinone oxidoreductase.
What are the official names of this protein?
Putative antiporter subunit mnhC2, Mrp complex subunit C2, Putative NADH-ubiquinone oxidoreductase subunit mnhC2.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GGNB1_RAT
Sequence: MAAQARTPRSRILGCSSMLRFLRSLVGSKGSSKSSNRPLNRSQPSSSPEQDVVSPTMGHQGGCGRKETRPRVLSATSSNGKREPRPRVLSAAPSNQRLRDASGLGTGDTGSQTLTSKDVLKLRAQGVEVTSVPTRGTWEVLEHLPEKKGEEGEPAGEVSGASDRAHFGQALEAEQGCLQWVSGPMVLPPEAFIKEEEDEHCLIDFGDLRLSSCKVGSTPWNYLLGLYKQLQKSAMTKAQRPDADAPQFALKDSSPTEERGEREEAVDESSLKWCAPRASSDDSNLKWCAPRNSTYQSPLQKTFRSTDTVGFVESELKKILAVQREARLWKVGNPEGRELLTQPDITLEEAGMVDGQHLLLEEMDEMGNWPPPE
What is the function of this protein?
Induces mitochondrial fragmentation, possibly by promoting DNM1L-dependent fission and may play a role in mitochondrial morphogenesis during spermatogenesis.
What are the official names of this protein?
Gametogenetin-binding protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein. Golgi apparatus. Mitochondrion intermembrane space.
Protein: RL19_KOSOT
Sequence: MDQYIRAIESQYIRKDFPEFRPGDTVRVYVKVREGNRERTQAFEGIVIKIRGGGVGKTFTVRRIGAGGIGVERIFPFASPAVEKVQVLRKGKVRRAKLYYVRNIRGKIRIKERRD
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: LPXD_METCA
Sequence: MHVTVSEILERFQPEGLITNHIGPDSVITRVAPIEDCAPGDLVFIDKPKYVGDVLQRKPAAVLTTPAIAAEFGESPALAVLIAPNVRLAIALIKQAYADRDVRDTEWPRIHPSAVIHASVEVPADAIIGPGVVIGADVVLGRGVVLMANVVIERGARIGAETVLHPGVTVCIDCEIGAGCILKPGCVIGSEGFGFAQDAQRRNYRIPHTGKVIIEDRVVIGANTTIDRATYGATVVRSGTIIDALVHLGHNVEIGEDCILCAHTGLSGSTRFGKRVIATGQTGTIDHITVADDSVLLHRAGLNTSIKQPGMYAGGPAQPLQQYLKNMAVMPRLHEIWSRLKKLEKAVAQLGSAE
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: TPPP2_MOUSE
Sequence: MASEAERTFHRFAVFGESSSSSKEITNKNFSKLCKDCDIMDGKAVTSTDVDIVFSKVKAKNARTINFQQFQEAMKELGQKRFKGKNPDEALQGVFKLMEGKDPATTGVTKSTTVGGVDRLTDTSKYTGTHKERFDESGKGKGIEGREETTDNSGYVSGYKGAGTYDKKNQ
What is the function of this protein?
Probable regulator of microtubule dynamics required for sperm motility (Probable).  In contrast to other members of the family, has no microtubule bundling activity (By similarity).
What are the official names of this protein?
Tubulin polymerization-promoting protein family member 2.
What is the protein family that this protein belongs to?
Belongs to the TPPP family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell projection, cilium, flagellum. Note=Present in the middle piece of sperm tail.
Protein: OTCC_LACLC
Sequence: MTSPLITKAEVNSVFQGRSLLAEKDFTPAEINYLVDFGLHLKALKQQNIPHHYLEGKNIALLFAKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGIKESTEDTARVLGSMFDAIERRGFSQKEVEDLAKYSGVPVWNGLTDDWHPTQMIADFMTVKENFGYLKGLTLVYVGDGRNNMANSLIVTGSMLGVNVHIVAPDSLHPSKEVMDIANKFAEKSGAKPLATSNIEEGVKGANIIYSDVWVSMGESNWEERVKLLTPYRITMDMLKMTGNADNGKLIFMHCLPAFHDTETEYGKEIKEKYGLTEMEVTDAVFRSKYARQFEEAENRMHSIKAIMAATLGNLFIPAVPEDFK
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, catabolic, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CML31_ARATH
Sequence: MAEIFESVDKNKDGKILWDEFAEAIRVFSPQITSEEIDKMFIVLDVDGDGQIDDVEFASCLMVNGGGEKDTEEEVVMKEAFDLYDMDGDGKISASEIHVVLKRLGEKHTMEDCVVMVQTVDKDSDGFVNFEEFKIMMNSNKESH
What is the function of this protein?
Potential calcium sensor.
What are the official names of this protein?
Probable calcium-binding protein CML31, Calmodulin-like protein 31.
Protein: PLSB_ECOSE
Sequence: MTFCYPCRAFALLTRGFTSFMSGWPRIYYKLLNLPLSILVKSKSIPADPAPELGLDTSRPIMYVLPYNSKADLLTLRAQCLAHDLPDPLEPLEIDGTLLPRYVFIHGGPRVFTYYTPKEESIKLFHDYLDLHRSNPNLDVQMVPVSVMFGRAPGREKGEVNPPLRMLNGVQKFFAVLWLGRDSFVRFSPSVSLRRMADEHGTDKTIAQKLARVARMHFARQRLAAVGPRLPARQDLFNKLLASRAIAKAVEDEARSKKISHEKAQQNAIALMEEIAANFSYEMIRLTDRILGFTWNRLYQGINVHNAERVRQLAHDGHELVYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFSRGYSVEYFVEGGRSRTGRLLDPKTGTLSMTIQAMLRGGTRPITLIPIYIGYEHVMEVGTYAKELRGATKEKESLPQMLRGLSKLRNLGQGYVNFGEPMPLMTYLNQHVPDWRESIDPIEAVRPAWLTPTVNNIAADLMVRINNAGAANAMNLCCTALLASRQRSLTREQLTEQLNCYLDLMRNVPYSTDSTVPSASASELIDHALQMNKFEVEKDTIGDIIILPREQAVLMTYYRNNIAHMLVLPSLMAAIVTQHRHISRDVLMEHVNVLYPMLKAELFLRWDRDELPDVIDALANEMQRQGLITLQDDELHINPAHSRTLQLLAAGARETLQRYAITFWLLSANPSINRGTLEKESRTVAQRLSVLHGINAPEFFDKAVFSSLVLTLRDEGYISDSGDAEPAETMKVYQLLAELITSDVRLTIESATQGEG
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, GPAT.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PUR5_PROM9
Sequence: MDYKTSGVDIEAGREFVSEIKQAVEGTHTSNVIDGIGGFGGLFRIPVDSFKKPVLVSGTDGVGTKLELAQSKNFHFEVGIDLVAMCMNDIITCGAKPLFFLDYIATGKLDKKQLLQVVQGISHGCGENNCSLLGGETAEMPGFYSNNKYDLAGFCVGIVDEDKLINGKKISENDLIIALKSNGVHSNGFSLVRKIIQNNNQLDKEFEKVSHLNFYDELLKPTKIYNNVVNQILSENIEIKAMSHITGGGIPENLPRCIPSDFIPYINTNSWEIPILFKFLKEKGTIPEKDFWNTFNLGVGFCLIIDKQFKDSILNICKDHDIDSWEIGKIVRKNDSTISKFLPEILT
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_VESOH
Sequence: MVIIQNNIHDLSVNEDDLSCILQKVVKEWGKGESELLVRLVDEAEIQNLNKVYRYKDEPTNVLSFPTDLPIEIDEKILGDVVICIQIVLKESIEQHKSFNNHLMHMAVHGTLHLLGYDHIDTKDAQNMANLERKILAKIGINNPY
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MP70_MYCTU
Sequence: MKVKNTIAATSFAAAGLAALAVAVSPPAAAGDLVGPGCAEYAAANPTGPASVQGMSQDPVAVAASNNPELTTLTAALSGQLNPQVNLVDTLNSGQYTVFAPTNAAFSKLPASTIDELKTNSSLLTSILTYHVVAGQTSPANVVGTRQTLQGASVTVTGQGNSLKVGNADVVCGGVSTANATVYMIDSVLMPPA
What are the official names of this protein?
Immunogenic protein MPT70.
What are the subcellular locations of this protein?
Secreted.