PharMolix/UniProtQA huggingface dataset:
Protein: RABX5_HUMAN
Sequence: MSLKSERRGIHVDQSDLLCKKGCGYYGNPAWQGFCSKCWREEYHKARQKQIQEDWELAERLQREEEEAFASSQSSQGAQSLTFSKFEEKKTNEKTRKVTTVKKFFSASSRVGSKKEIQEAKAPSPSINRQTSIETDRVSKEFIEFLKTFHKTGQEIYKQTKLFLEGMHYKRDLSIEEQSECAQDFYHNVAERMQTRGKVPPERVEKIMDQIEKYIMTRLYKYVFCPETTDDEKKDLAIQKRIRALRWVTPQMLCVPVNEDIPEVSDMVVKAITDIIEMDSKRVPRDKLACITKCSKHIFNAIKITKNEPASADDFLPTLIYIVLKGNPPRLQSNIQYITRFCNPSRLMTGEDGYYFTNLCCAVAFIEKLDAQSLNLSQEDFDRYMSGQTSPRKQEAESWSPDACLGVKQMYKNLDLLSQLNERQERIMNEAKKLEKDLIDWTDGIAREVQDIVEKYPLEIKPPNQPLAAIDSENVENDKLPPPLQPQVYAG
What is the function of this protein?
Rab effector protein acting as linker between gamma-adaptin, RAB4A or RAB5A.  Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes.  Stimulates nucleotide exchange on RAB5A.  Can act as a ubiquitin ligase (By similarity).
What are the official names of this protein?
Rab5 GDP/GTP exchange factor, RAP1, Rabaptin-5-associated exchange factor for Rab5, Rabex-5.
What are the subcellular locations of this protein?
Cytoplasm. Early endosome. Recycling endosome.
Protein: KLP1_CHLRE
Sequence: MVKQAVKVFVRTRPTATSGSGLKLGPDGQSVSVNVPKDLSAGPVNNQQEQFSFKFDGVLENVSQEAAYTTLAHEVVDSLMAGYHGTIFAYGQTGAGKTFTMSGGGTAYAHRGLIPRAIHHVFREVDMRADKMYRVHVSYLEIYNEQLYDLLGDTPGTSDALAVLEDSNSNTYVRGLTLVPVRSEEEALAQFFLGEQGRTTAGHVLNAESSRSHTVFTIHVEMRTSDAASERAVLSKLNLVDLAGSERTKKTGVTGQTLKEAQFINRSLSFLEQTVNALSRKDTYVPFRQTKLTAVLRDALGGNCKTVMVANIWAEPSHNEETLSTLRFASRVRTLTTDLALNESNDPALLLRRYERQIKELKAELAMRDTLSGKGRVSYDDLTDDELRELHATCRRFLHGEAEPEDLPADSMKRVRETFKALRAVHVAIKADMATQMATLRRATEEGSGAAARGGDSAGPSGVGDVDLRATGGFTVGHAPLDARPPVRSELGSPGAGASGAEALGEPRSPGGGLHAQASSHTDAGSNWGDAGPLSSPGGTRLAGIFGVSGDRNAVFRRYKVDVGEGRELAASLKAASIALADTKASIRSLGASVNDAKQRIDELSSALALRRGATPAGGDGEVLDSEAYALMQELKSAKSRYRTDFDSLKSAREELEPQIQAVAVARAGLLEAFDRWAAAQSDTTLKRMATAGRAMSGIAPGEEDEMDAGEQFERMQIARISERDPDSLAFHTALKRTGAAVSRPATVATGGNAKAAAMATRKMEHTQAVNRGLAR
What is the function of this protein?
May play a role in rotation or twisting of the central pair microtubules of the flagella axoneme.
What are the official names of this protein?
Kinesin-like protein KLP1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, flagellum axoneme. Note=Bound to the central pair microtubule C2 or to projections that are attached to C2.
Protein: PFKA_STAAE
Sequence: MKKIAVLTSGGDSPGMNAAVRAVVRTAIYNEIEVYGVYHGYQGLLNDDIHKLELGSVGDTIQRGGTFLYSARCPEFKEQEVRKVAIENLRKRGIEGLVVIGGDGSYRGAQRISEECKEIQTIGIPGTIDNDINGTDFTIGFDTALNTIIGLVDKIRDTASSHARTFIIEAMGRDCGDLALWAGLSVGAETIVVPEVKTDIKEIADKIEQGIKRGKKHSIVLVAEGCMTAQDCQKELSQYINVDNRVSVLGHVQRGGSPTGADRVLASRLGGYAVDLLMQGETAKGVGIKNNKIVATSFDEIFDGKDHKFDYSLYELANKLSI
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPSF_BACSU
Sequence: MNDILFIIQARMGSTRLPGKVLRPLGSNRLLDILVHRVRQSAFYQKDRDNLVIATSDKETDDILEAHCIKQGFRVFRGSEERVLDRFVKVIEAVKPSVIIRLTGDNPFVDPELLDVMIQAHFDQGSDYTYILNAPLGICGEVVNANLLIDISRIQALEDQYQEHVTLYIRNHPALYRVQFLEAPERFRAPQYRLTIDTKEDYESIKALYQKAGERPDVSASELITLLNRNPDAATEREAD
What are the official names of this protein?
Spore coat polysaccharide biosynthesis protein SpsF.
What is the protein family that this protein belongs to?
Belongs to the CMP-NeuNAc synthase family.
Protein: SELO_SALCH
Sequence: MTLSFTARWRDELPATYTALLPTPLKNARLIWYNDKLAQQLAIPASLFDVTNGAGVWGGETLLPGMSPVAQVCSGHQFGVWAGQLGDGRGILLGEQLLADGSTLDWHLKGAGLTPYSRMGDGRAVLRSTIRESLASEAMHYLGIPTTRALSIVASDTPVQRETQETGAMLMRLAQSHMRFGHFEHFYYRREPEKVQQLADFAIRHYWPQWQDVPEKYVLWFEEVAARTGRLIAEWQTVGFSHGVMNTDNMSILGLTIDYGPFGFLDDYDPGFIGNHSDHQGRYRFDNQPSVALWNLQRLAQTLTPFIEIDALNRALDRYQDALLTHYGQRMRQKLGFFTEQKDDNVLLNELFSLMAREGSDYSRTFRMLSHTEQQSASSPLRDTFIDRAAFDAWFDRYRARLRTEAVDDALRQQQMQRVNPAVVLRNWLAQRAIDAAEQGDMAELHWLHEVLRQPFTDRDDDYASRPPEWGKRLEVSCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: AMD_HUMAN
Sequence: MAGRVPSLLVLLVFPSSCLAFRSPLSVFKRFKETTRPFSNECLGTTRPVVPIDSSDFALDIRMPGVTPKQSDTYFCMSMRIPVDEEAFVIDFKPRASMDTVHHMLLFGCNMPSSTGSYWFCDEGTCTDKANILYAWARNAPPTRLPKGVGFRVGGETGSKYFVLQVHYGDISAFRDNNKDCSGVSLHLTRLPQPLIAGMYLMMSVDTVIPAGEKVVNSDISCHYKNYPMHVFAYRVHTHHLGKVVSGYRVRNGQWTLIGRQSPQLPQAFYPVGHPVDVSFGDLLAARCVFTGEGRTEATHIGGTSSDEMCNLYIMYYMEAKHAVSFMTCTQNVAPDMFRTIPPEANIPIPVKSDMVMMHEHHKETEYKDKIPLLQQPKREEEEVLDQGDFYSLLSKLLGEREDVVHVHKYNPTEKAESESDLVAEIANVVQKKDLGRSDAREGAEHERGNAILVRDRIHKFHRLVSTLRPPESRVFSLQQPPPGEGTWEPEHTGDFHMEEALDWPGVYLLPGQVSGVALDPKNNLVIFHRGDHVWDGNSFDSKFVYQQIGLGPIEEDTILVIDPNNAAVLQSSGKNLFYLPHGLSIDKDGNYWVTDVALHQVFKLDPNNKEGPVLILGRSMQPGSDQNHFCQPTDVAVDPGTGAIYVSDGYCNSRIVQFSPSGKFITQWGEESSGSSPLPGQFTVPHSLALVPLLGQLCVADRENGRIQCFKTDTKEFVREIKHSSFGRNVFAISYIPGLLFAVNGKPHFGDQEPVQGFVMNFSNGEIIDIFKPVRKHFDMPHDIVASEDGTVYIGDAHTNTVWKFTLTEKLEHRSVKKAGIEVQEIKEAEAVVETKMENKPTSSELQKMQEKQKLIKEPGSGVPVVLITTLLVIPVVVLLAIAIFIRWKKSRAFGDSEHKLETSSGRVLGRFRGKGSGGLNLGNFFASRKGYSRKGFDRLSTEGSDQEKEDDGSESEEEYSAPLPALAPSSS
What is the function of this protein?
Bifunctional enzyme that catalyzes the post-translational modification of inactive peptidylglycine precursors to the corresponding bioactive alpha-amidated peptides, a terminal modification in biosynthesis of many neural and endocrine peptides (PubMed:12699694).  Alpha-amidation involves two sequential reactions, both of which are catalyzed by separate catalytic domains of the enzyme.  The first step, catalyzed by peptidyl alpha-hydroxylating monooxygenase (PHM) domain, is the copper-, ascorbate-, and O2- dependent stereospecific hydroxylation (with S stereochemistry) at the alpha-carbon (C-alpha) of the C-terminal glycine of the peptidylglycine substrate (PubMed:12699694).  The second step, catalyzed by the peptidylglycine amidoglycolate lyase (PAL) domain, is the zinc-dependent cleavage of the N-C-alpha bond, producing the alpha-amidated peptide and glyoxylate (PubMed:12699694).  Similarly, catalyzes the two-step conversion of an N-fatty acylglycine to a primary fatty acid amide and glyoxylate (By similarity).
What are the official names of this protein?
Peptidyl-glycine alpha-amidating monooxygenase, PAM.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the copper type II ascorbate-dependent monooxygenase family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle membrane; Single-pass membrane protein. Note=Secretory granules. SUBCELLULAR LOCATION: [Isoform 1]: Membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 3]: Secreted. Note=Secreted from secretory granules. SUBCELLULAR LOCATION: [Isoform 4]: Secreted. Note=Secreted from secretory granules.
Protein: PLCB_HUMAN
Sequence: MELWPCLAAALLLLLLLVQLSRAAEFYAKVALYCALCFTVSAVASLVCLLRHGGRTVENMSIIGWFVRSFKYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLMEVLPERCVQIAKRELLFLGPVGLIMYLGGVFFINRQRSSTAMTVMADLGERMVRENLKVWIYPEGTRNDNGDLLPFKKGAFYLAVQAQVPIVPVVYSSFSSFYNTKKKFFTSGTVTVQVLEAIPTSGLTAADVPALVDTCHRAMRTTFLHISKTPQENGATAGSGVQPAQ
What is the function of this protein?
Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
What are the official names of this protein?
1-acyl-sn-glycerol-3-phosphate acyltransferase beta, 1-acylglycerol-3-phosphate O-acyltransferase 2, 1-AGP acyltransferase 2, 1-AGPAT 2, Lysophosphatidic acid acyltransferase beta, LPAAT-beta.
What is the protein family that this protein belongs to?
Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ISPE_FRATF
Sequence: MANIKAKKYYSYAKINLFLHILNKRTDGYHNLQTWFTFLDLKDQLTFSFNNSREINISSNISIAAKQDNLVYKAIKKFQQSYRVQDIGVDIEIKKNIPMGAGLGGGSSNAATTLIALRDYYLPQLSNEEMIPLAVKLGADVPIFVYGKSAWAEGIGEILYHKDFSPQYALLIKPDIHISTKEFFTSEDLIKSSVLISKDLGFDKSIMHNDFENVFYAKYPEFSQYLKELDSDFRMTGTGSCFYLLSADKNKLEQLTRKINKPLDKWLVKTLNYVY
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: HIS6_ECO24
Sequence: MLAKRIIPCLDVRDGQVVKGVQFRNHEIIGDIVPLAKRYAEEGADELVFYDITASSDGRVVDKSWVSRVAEVIDIPFCVAGGIKSLDDAAKILSFGADKISINSPALADPTLITRLADRFGVQCIVVGIDTWYDGETGKYHVNQYTGDETRTRVTQWETLDWVQEVQKRGAGEIVLNMMNQDGVRNGYDLEQLKKVREVCHVPLIASGGAGTMEHFLEAFRDADVDGALAASVFHKQIINIGELKAYLATQGVEIRIC
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSHA_RHOE4
Sequence: MHISRPRRVAVLSVHTSPLAQPGTGDAGGMNVYVLQSAIQLAKRGVEVEIFTRATSSADAPVVDAAPGVRVRNIAAGPFEGLDKADLPTQLCAFVAGVLREEARHEPGYYSLIHSHYWLSGQVGWLARDRWGVPLVHTAHTLAAVKNLSLAEGDTPEPAARQIGEQQVVAESDRLVANTTDEAKALHELYGADPTRIDVVAPGADLTRYRPGDRDSARASLGLDPGEIVVTFVGRIQPLKAPDVLLRAAAEVISRSPGLPLRILVVGGPSGTGLARPDVLIELARSLGITAQVTFLPPQAPERLADVYRASDLVAVPSYSESFGLVAIEAQACGTPVIAADVGGLGVAVRNGETGLLVQGHRTEDWAGALESLVTAPTRLAELAAQAPRHAENFSWEHTADGLLESYRKAAVNYNNGTGPSDFSPRRARGLWRLRRTGGVRT
What is the function of this protein?
Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
What are the official names of this protein?
D-inositol 3-phosphate glycosyltransferase, N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase, GlcNAc-Ins-P N-acetylglucosaminyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. MshA subfamily.
Protein: RS4_YERPY
Sequence: MARYLGPKLKLSRREGTDLFLKSGVRAIDTKCKIEQPPGQHGARKPRLSDYGVQLREKQKVRRIYGVLERQFRNYYKEAARLKGNTGANLLQLLEGRLDNVVYRMGFGATRAESRQLVSHKAIMVNGRVVNIASYQVSPNDVVSIREKAKKQSRVKAALELAEQREKPTWLEVDAVKMEGVFKRIPERTDLSADINEHLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: DEOB_LISMF
Sequence: MPDKFKRVHVVVMDSVGIGEAPDAAKFGDFDVDTFGHIAKHVGGLKMPEMGKLGLSNIREIDGIKKAEKPLAYYTKMQEASNGKDTMTGHWEIMGLYIDTPFRVFPDGFPDDLINQIEEKTGRKVIGNKPASGTEIMAELGEEHVKTGALIVYTSADSVLQIAAHEDVVPLEELYEICEFCRKITLDDPYMLGRIIARPFVGEPGAFVRTPNRHDYALKPFKPTVMDALKDGGKDVIAIGKISDIFDGEGVTESIRTKSNMDGMDQFIAVLDKDFNGMSFLNLVDFDALFGHRRDPQGYADALVDFDGRLVEVMEKLTDDDLLIITADHGNDPTYSGTDHTREFVPLLVYSPRFKNGGSELELRKTFADLGATVADNFEVKMPEYGTSFLKDLK
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CASZ1_HUMAN
Sequence: MDLGTAEGTRCTDPPAGKPAMAPKRKGGLKLNAICAKLSRQVVVEKRADAGSHTEGSPSQPRDQERSGPESGAARAPRSEEDKRRAVIEKWVNGEYSEEPAPTPVLGRIAREGLELPPEGVYMVQPQGCSDEEDHAEEPSKDGGALEEKDSDGAASKEDSGPSTRQASGEASSLRDYAASTMTEFLGMFGYDDQNTRDELARKISFEKLHAGSTPEAATSSMLPTSEDTLSKRARFSKYEEYIRKLKAGEQLSWPAPSTKTEERVGKEVVGTLPGLRLPSSTAHLETKATILPLPSHSSVQMQNLVARASKYDFFIQKLKTGENLRPQNGSTYKKPSKYDLENVKYLHLFKPGEGSPDMGGAIAFKTGKVGRPSKYDVRGIQKPGPAKVPPTPSLAPAPLASVPSAPSAPGPGPEPPASLSFNTPEYLKSTFSKTDSITTGTVSTVKNGLPTDKPAVTEDVNIYQKYIARFSGSQHCGHIHCAYQYREHYHCLDPECNYQRFTSKQDVIRHYNMHKKRDNSLQHGFMRFSPLDDCSVYYHGCHLNGKSTHYHCMQVGCNKVYTSTSDVMTHENFHKKNTQLINDGFQRFRATEDCGTADCQFYGQKTTHFHCRRPGCTFTFKNKCDIEKHKSYHIKDDAYAKDGFKKFYKYEECKYEGCVYSKATNHFHCIRAGCGFTFTSTSQMTSHKRKHERRHIRSSGALGLPPSLLGAKDTEHEESSNDDLVDFSALSSKNSSLSASPTSQQSSASLAAATAATEAGPSATKPPNSKISGLLPQGLPGSIPLALALSNSGLPTPTPYFPILAGRGSTSLPVGTPSLLGAVSSGSAASATPDTPTLVASGAGDSAPVAAASVPAPPASIMERISASKGLISPMMARLAAAALKPSATFDPGSGQQVTPARFPPAQVKPEPGESTGAPGPHEASQDRSLDLTVKEPSNESNGHAVPANSSLLSSLMNKMSQGNPGLGSLLNIKAEAEGSPAAEPSPFLGKAVKALVQEKLAEPWKVYLRRFGTKDFCDGQCDFLHKAHFHCVVEECGALFSTLDGAIKHANFHFRTEGGAAKGNTEAAFPASAAETKPPMAPSSPPVPPVTTATVSSLEGPAPSPASVPSTPTLLAWKQLASTIPQMPQIPASVPHLPASPLATTSLENAKPQVKPGFLQFQENDPCLATDCKYANKFHFHCLFGNCKYVCKTSGKAESHCLDHINPNNNLVNVRDQFAYYSLQCLCPNQHCEFRMRGHYHCLRTGCYFVTNITTKLPWHIKKHEKAERRAANGFKYFTKREECGRLGCKYNQVNSHFHCIREGCQFSFLLKHQMTSHARKHMRRMLGKNFDRVPPSQGPPGLMDAETDECMDYTGCSPGAMSSESSTMDRSCSSTPVGNESTAAGNTISMPTASGAKKRFWIIEDMSPFGKRRKTASSRKMLDEGMMLEGFRRFDLYEDCKDAACQFSLKVTHYHCTRENCGYKFCGRTHMYKHAQHHDRVDNLVLDDFKRFKASLSCHFADCPFSGTSTHFHCLRCRFRCTDSTKVTAHRKHHGKQDVISAAGFCQFSSSADCAVPDCKYKLKCSHFHCTFPGCRHTVVGMSQMDSHKRKHEKQERGEPAAEGPAPGPPISLDGSLSLGAEPGSLLFLQSAAAGLGLALGDAGDPGPPDAAAPGPREGAAAAAAAAGESSQEDEEEELELPEEEAEDDEDEDDDEDDDDEDDDEDDDDEDLRTDSEESLPEAAAEAAGAGARTPALAALAALGAPGPAPTAASSP
What is the function of this protein?
Transcriptional activator (PubMed:23639441, PubMed:27693370).  Involved in vascular assembly and morphogenesis through direct transcriptional regulation of EGFL7 (PubMed:23639441).
What are the official names of this protein?
Zinc finger protein castor homolog 1, Castor-related protein, Putative survival-related protein, Zinc finger protein 693.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPPH_CUPPJ
Sequence: MLDREGFRPNVGIILINARNEVFWGKRIGEHSWQFPQGGIKYGETPEQAMYRELHEEIGLLPEHVRIVGRTRDWLRYEVPDKFIRREIRGHYRGQKQIWFLLRMAGRDCDVHLRATEHPEFDAWRWSDYWVPLEAVIEFKRDVYQLALTELSRFLNRNPRVPLSPYGVHHGRHGSGQRYAQQPGQPPTLAQRRPLQPVTQVAPVAPAAEAVQAVESDAVLPATPAPNPTES
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: RL4_RUTMC
Sequence: MKFKVLNISTNKSSTIEVADTVFARGFNQALVHQVTTAYMSGGRQGSKAQKNRSTVSGGSKRPWAQKGTGRARAGTTRGPIWRSGGVTFSAAPRGYAQKVNKKMYKGAISVIFSELARSERLKVVSEFNIKEIKTKNITALLKALNVKDVLLMTDELDENLYLSSRNLYHVGVCDIQSIDPVSLIGYDNVVVTEIALKKIEAML
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: EIF3G_AEDAE
Sequence: MPALDEIKSSWADEVELDSGSLPPPTEIIENGQKIVTEYKYNKDDKKVKVVRTYKITRLVVPKSIAMRKNWSKFGDSSNDKPGPNPQTTMVSEDVYMQFVSNKEEEQKSDNALDSLKNIAKCRICEGEHWSLSCPYKGTAYEAGKAKPVVPVQQEMAPTTAKSGKYVPPSMRDSQKPGMGGNPRGRDDTTAIRISNLSEAMTEADLEELVKKIGPHSKMFLARDKNTGLCKGFAYVHFKSRRDAATAIELLNGHGYDHLILNVEWSKPQNPQ
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.  This subunit can bind 18S rRNA.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit G, eIF3g, Eukaryotic translation initiation factor 3 RNA-binding subunit, eIF-3 RNA-binding subunit, Eukaryotic translation initiation factor 3 subunit 4.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit G family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y727_GLAP5
Sequence: MKLGKIALAMTALIAGTTAFAGTITGSSNVTFLAFDGQKVRRNTNLQVNDTNLHQVVVEISSIYQSGSDSAFFESQPIILTFEGSTEDIKILAPSLNSEFDIAQFKKSPSFKIETVSGKKLTYKQDFLKGEGFMPNSNIINNLANYNIGEGVAAVQKFALSTMPITMANNTNKVNKGKIVVQGENVTEQQLQYWFQQADKETQKRFLDWAKKQ
What are the official names of this protein?
UPF0319 protein HAPS_0727.
What is the protein family that this protein belongs to?
Belongs to the UPF0319 family.
Protein: RPOZ_WOLPM
Sequence: MAESIVEKCIERVSNRFKLVLLASQRTHDLNTGASNPIQAAKFKGHKNTIVSLHEIAGKQVDTHELFSLLVGRCKEYMKGNMNNVYSSNTSKLANLLNFSDNTDLDASQESQDYEVDGEIDDEINDQDGDEEVSV
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: ARNA_ECO45
Sequence: MKTVVFAYHDMGCLGIEALLAAGYEISAIFTHTDNPGEKAFYGSVARLAAERGIPVYAPDNVNHPLWVERIAQLSPEVIFSFYYRHLICDEILQLAPRGAFNLHGSLLPKYRGRAPLNWVLVNGETETGVTLHRMVKRADAGAIVAQLRVAIAPDDIAITLHHKLCHAARQLLEQTLPAIKHGNILEIAQRENEATCFGRRTPDDSFLEWHKSASVLHNMVRAVADPWPGAFSYVGNQKFTVWSSRVHPHASKAQPGSVISVAPLLIACGDGALEIVTGQAGDGITMQGSQLAQTLGLVQGSRLNSQPACAARRRTRVLILGVNGFIGNHLTERLLREDHYEVYGLDIGSDAISRFLNHPHFHFVEGDISIHSEWIEYHVKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLRIIRYCVKYRKRIIFPSTSEVYGMCSDKYFDEDHSNLIVGPVNKPRWIYSVSKQLLDRVIWAYGEKEGLQFTLFRPFNWMGPRLDNLNAARIGSSRAITQLILNLVEGSPIKLIDGGKQKRCFTDIRDGIEALYRIIENAGNRCDGEIINIGNPENEASIEELGEMLLASFEKHPLRHYFPPFAGFRVVESSSYYGKGYQDVEHRKPSIRNARRCLNWEPKIDMQETIDETLDFFLRTVDLTDKPS
What is the function of this protein?
Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Bifunctional polymyxin resistance protein ArnA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
Protein: NUOB_FRATT
Sequence: MGIGNENKGFITASADALINWVRTGSLWPVTTGLACCAVEMMHAGAARYDLDRFGIVFRPSPRQSDVLIVAGTLCNKMAPALRQVYDQMPDPKWVISMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALVYGIIQLQNKIIRKDTIARK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PPR93_ARATH
Sequence: MRRSTTISIASKANKFLNLCLLQKGNPVIVPFISRFWGRTFSTKRSSMNLEEEIDLFCKMIQSRPLPSIVDFSKVLSKIAKSKNYDLVISLFHHMEVCGIGHDLYSYNIVINCLCRCSRFVIALSVVGKMMKFGYEPDVVTVSSLINGFCQGNRVFDAIDLVSKMEEMGFRPDVVIYNTIIDGSCKIGLVNDAVELFDRMERDGVRADAVTYNSLVAGLCCSGRWSDAARLMRDMVMRDIVPNVITFTAVIDVFVKEGKFSEAMKLYEEMTRRCVDPDVFTYNSLINGLCMHGRVDEAKQMLDLMVTKGCLPDVVTYNTLINGFCKSKRVDEGTKLFREMAQRGLVGDTITYNTIIQGYFQAGRPDAAQEIFSRMDSRPNIRTYSILLYGLCMNWRVEKALVLFENMQKSEIELDITTYNIVIHGMCKIGNVEDAWDLFRSLSCKGLKPDVVSYTTMISGFCRKRQWDKSDLLYRKMQEDGLLPL
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At1g62720.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
Protein: HRCA_ALKMQ
Sequence: MQLNERKLKILQAIIQDYIYTAEPVGSRSLSKKYDLQVSPATIRNEMADLEDMGYLIQPYTSAGRIPSDKGYRLYVDHLLQLEKNMVIQRDQIRSDLLNRFGEIEQLLQYSSKILSQLTNYTTIALAPQIKEVRLKHIQLIPMDEHHLLGIIITDTGLIKKTVLQVPEGLDAEAISKISEVINGRLQGVAIKGIPGEFTEEFTHELEQLSHGFDSVIPKMFQTLEELDKIELFLHGTTNIFNFPEFNDIFKAKSFLSMLEEKELISQLILSSSHKGMNATIGSENIYKEAKEYSLVTATYKIDEDVIGFVSIIGPTRMDYSNVMSTMGQVNKYINEVLKGKYK
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: TF2AA_RAT
Sequence: MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKTLWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQTQQVLIPASQQATAPQVIVPDSKLIQHMNASSITSAAATAATLALPAGVTPVQQILTNSGQLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTGVIIQPQQILFTGNKTQVIPTTVAAPTPAQAQIPAAGQQQPQAQPAQQQAPLVLQVDGTGDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW
What is the function of this protein?
TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation.  TFIIA in a complex with TBP mediates transcriptional activity (By similarity).
What are the official names of this protein?
Transcription initiation factor IIA subunit 1, General transcription factor IIA subunit 1.
What is the protein family that this protein belongs to?
Belongs to the TFIIA subunit 1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EFP_BLOPB
Sequence: MVLYNINEFRTGLKIIQNREPCVIISHESIKPGKGQAFSRVRFRQIISGKILEKTFKSGDFLESANIMEIRLVYVYHDNEFWYFMDEKNFEEIAVAAKIIGTNIKWITTQLHYIVTLWNKVPILVTPPDSIELKIIKITPIKKNSTGSSGIKLATVSTGAIVKVPFFIQLGELIKINTRSGIYISRAK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.