PharMolix/UniProtQA huggingface dataset:
Protein: SPS1_PONAB
Sequence: MSTRESFNPESYELDKSFRLTRFTELKGTGCKVPQDVLQKLLESLQENHFQEDEQFLGAVMPRLGIGMDTCVIPLRHGGLSLVQTTDYIYPIVDDPYMMGRIACANVLSDLYAMGVTECDNMLMLLGVSNKMTDRERDKVMPLIIQGFKDAAEEAGTSVTGGQTVLNPWIVLGGVATTVCQPNEFIMPDNAVPGDVLVLTKPLGTQVAVAVHQWLDIPEKWNKIKLVVTQEDVELAYQEAMMNMARLNRTAAGLMHTFNAHAATDITGFGILGHAQNLAKQQRNEVSFVIHNLPVLAKMAAVSKACGNMFGLMHGTCPETSGGLLICLPREQAARFCAEIKSPKYGEGHQAWIIGIVEKGNRTARIIDKPRIIEVAPQVATQNVNPTPGATS
What is the function of this protein?
Synthesizes selenophosphate from selenide and ATP.
What are the official names of this protein?
Selenide, water dikinase 1, Selenium donor protein 1, Selenophosphate synthase 1.
What is the protein family that this protein belongs to?
Belongs to the selenophosphate synthase 1 family. Class II subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Nucleus membrane; Peripheral membrane protein.
Protein: RSMA_CAMC1
Sequence: MIKAKKHFGQNFLQDKATLDKIIQAIPKDVENVVEIGPGLGDLTFRLLQIYKTTSFEIDRELFQILKVKFANEIQNGQLKLFCKDALEQWQQEGGLSSENYFLVANLPYYVATKMILNAIDDEKCLGLIVMIQKEVALKFSAKSKDKEFSALSILASLQGRCELLFDVDAKLFNPPPKVTSSVIKLQKTKKIFGKDGIFKDAKQYEAFKAFLRAAFASPRKTLLKNLSTNFDKKALEEIFENMNLATNLRPHELDVDSYLKIFEITKEDNERQKRRESCN
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_BACCQ
Sequence: MSHLLTMSELSEVEISEILKDAEDFANGKESKTTEQTFVANLFFENSTRTRFSFEVAEKRLGLDVLNFSADASSVQKGETLYDTIRTLESIGTKAVVIRHEQDRYFDELKDQVNIPILNAGDGCGNHPTQCLLDLLTIKQEFGRFEGLKIAIVGDVRHSRVARSNAEALTKLGATIYFASPEEWKDEDNTFGTYKPLDELVPEVDVMMLLRVQHERHDHYETDIMKEYHEKHGLTVEREKRMKEGSIIMHPAPVNRDVEIASELVECERSRIFKQMENGVYVRMAVLKRALPNVLGGMKHELFV
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: RF1_YERPG
Sequence: MKSSIVAKLEALQERHEEVLAYLGDASVIADQDRFRALSREYAQLTDVTRCFKEWRSAQDDIEAAEMMLDDLEMREMAQEELKIAKARSEELEQQLQVLLLPKDPDDERDCFLEIRAGTGGDEAAIFAGDMFRMYSRYAETRRWKVEIMSASEGEHGGYKEIIAKISGDGVFGQLKFESGGHRVQRVPETESQGRIHTSACTVAVMPAIPEAELPEINAGDLRIDTFRSSGAGGQHVNTTDSAIRITHIPTGIVVECQDERSQHKNKAKAMSVLGARIRAAEMQKRQLAEASERRNLLGTGDRSDRNRTYNFPQGRVTDHRINLTLYRLDEVMEGKLDMLIQPIVQEYQADQLSALSEQD
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DIOX3_PAPSO
Sequence: METPILIKLGNGLSIPSVQELAKLTLAEIPSRYTCTGESPLNNIGASVTDDETVPVIDLQNLLSPEPVVGKLELDKLHSACKEWGFFQLVNHGVDALLMDNIKSEIKGFFNLPMNEKTKYGQQDGDFEGFGQPYIESEDQRLDWTEVFSMLSLPLHLRKPHLFPELPLPFRETLESYLSKMKKLSTVVFEMLEKSLQLVEIKGMTDLFEDGLQTMRMNYYPPCPRPELVLGLTSHSDFSGLTILLQLNEVEGLQIRKEERWISIKPLPDAFIVNVGDILEIMTNGIYRSVEHRAVVNSTKERLSIATFHDSKLESEIGPISSLVTPETPALFKRGRYEDILKENLSRKLDGKSFLDYMRM
What is the function of this protein?
Non-heme dioxygenase catalyzing the conversion of codeine to morphine.  Catalyzes also, with lower efficiency, the 3-O-demethylation of thebaine to oripavine and of (S)-scoulerine to 3-O-demethylscoulerine.  No activity with (S)-reticuline, salutaridine, papaverine, (S)-corytuberine, oripavine, pavine or noscapine.
What are the official names of this protein?
Codeine O-demethylase.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: LSRR_ECOSM
Sequence: MTINDSVISEQGMCEEEQVARIAWFYYHDGLTQSEISDRLGLTRLKVSRLLEKGHQSGIIRVQINSRFEGCLEYETQLCRQFSLQHVRVIPGLADADVGGRLGIGAAHMLMSLLQPQQMLAIGFGEATMNTLQRLSGFISSQQIRLVTLSGGVGSYMTGIGQLNAACSVNIIPAPLRASSADIAHTLKNENCVKDVLLAAQAADVAIVGIGAVSQQDDATIIRSGYISQGEQLMIGRKGAVGDILGYFFDAKGDVVTDIKIHNELIGLPLSALKTIPVRVGVAGGENKAEAIAAAMKGGYINALVTDQDTAAAILRS
What is the function of this protein?
Regulates transcription of many different genes.  In the absence of autoinducer 2 (AI-2), represses transcription of the lsrACDBFG operon and its own transcription.  In the presence of AI-2, LsrR is inactivated by binding phospho-AI-2, leading to the transcription of the lsr genes (By similarity).
What are the official names of this protein?
Transcriptional regulator LsrR.
What is the protein family that this protein belongs to?
Belongs to the SorC transcriptional regulatory family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URK_SALEP
Sequence: MTDQSHQCVIIGIAGASASGKSLIASTLYRELREQVGDEHIGVIPEDSYYKDQSHLSMEERVKTNYDHPNAMDHSLLFQHLQALKRGSAIELPVYSYVEHTRMQETVRVEPKKVIILEGILLLTDARLREEMNFSIFVDTPLDICLMRRIKRDVNERGRSMDSVMAQYQKTVRPMFLQFIEPSKQYADIIVPRGGKNRIAIDILKAKISQFFE
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCGL_SALG2
Sequence: MRQVTIPLIQSKSMFCVIYRSSKRDQTYLYVEKKDDFSRVPEALMKGFGQPQLAMMLPLDGRKKLVNAELEKVKQALSEQGYYLQLPPPPEDLLKQHLSSVGQNTSPADR
What are the official names of this protein?
Protein YcgL.
Protein: Y1854_ACIAC
Sequence: MPSFDTVCEANLVEVKNAVENSAKEIGTRFDFKGTSAAIEIKDKEITLFGDAEFQLQQVEDILRNKLTKRNVDVRFLDKGDVQKIGGDKVKQVIKVRNGIESELAKKIQKLVKESKIKVQAAIQEEKVRVTGAKRDDLQAVMALIRKDITDVPLSFDNFRD
What are the official names of this protein?
UPF0234 protein Aave_1854.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: AQP9_RAT
Sequence: MPSEKDGAKKSLMQRLALKSRIAKETLSEFLGTFIMIVLGCSSIAQAVLSRERFGGIITINIGFASAVVMALYVTFGISGGHINPAVSFAMCAFGRMEWFKFPFYVGAQFLGAFVGAATVFGIYYDGLMAFAGGKLLVVGENATAFIFATYPAPFISTPGAFVDQVVSTMFLLLIVFAMFDSRNLGVPRGLEPVVIGLLIIVLSCSLGLNSGCAMNPARDLSPRLFTALAGWGFEVFTVGNNFWWIPVVGPMIGAFLGGLIYILFIQMHHSKLDPDMKAEPSENNLEKHELSVIM
What is the function of this protein?
Forms a water channel with a broad specificity.  Also permeable glycerol and urea.  Mediates passage of a wide variety of small, non-charged solutes including carbamides, polyols, purines, and pyrimidines.
What are the official names of this protein?
Aquaporin-9, AQP-9, Aquaglyceroporin-9.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FENR_LACGA
Sequence: MEKYDLAIIGAGPIGLFAASFANLHGLKTISFDALDEIGGQINMLYPQKNIKDIPAFPSIKGKKLVSQLLEQNINTKFILSHKVKEISFLENENILVDKKYEVKSLLIATGLGAFKPKTLPLSTTLDVNQHIHYSMQHPEIFANKKVAILGGGDSALDWALELANTSDVFLIHRRNEFRGLESSVNKLKSLKNVELLTPYLPKDLQLNNNRMELVLHKVGASQDFVTKNVDEILVAYGFKSDNRQLRKWGIKLDHNLIAVSQKMHTNLPHVYAIGDAITYPGRVPMIALGFGEAQIAISNIMQDLFPEKTMTFHSTSI
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: DCUP_MYCBO
Sequence: MSTRRDLPQSPYLAAVTGRKPSRVPVWFMRQAGRSLPEYRALRERYSMLAACFEPDVACEITLQPIRRYDVDAAILFSDIVVPLRAAGVDLDIVADVGPVIADPVRTAADVAAMKPLDPQAIQPVLVAASLLVAELGDVPLIGFAGAPFTLASYLVEGGPSRHHAHVKAMMLAEPASWHALMAKLTDLTIAFLVGQIDAGVDAIQVFDSWAGALSPIDYRQYVLPHSARVFAALGEHGVPMTHFGVGTAELLGAMSEAVTAGERPGRGAVVGVDWRTPLTDAAARVVPGTALQGNLDPAVVLAGWPAVERAARAVVDDGRRAVDAGAAGHIFNLGHGVLPESDPAVLADLVSLVHSL
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_RUMCH
Sequence: MFRDSAKIYVKAGNGGNGMVSFHREKYIAAGGPDGGDGGKGGDVIFVVDEGLNTLIDFRYKKNFKAEPGQDGGTSNRSGKNGEDLIIKVPLGTVVKDELTDMVLVDLIKPGQTCVIAKGGRGGKGNQHFATPTRQVPNFAKSGDLGEEYSLILEMKMIADVGLVGYPNVGKSTILSMVSAAKPKIANYHFTTLVPNLGVVQIEHGKSFVIADIPGLIEGAHEGVGLGHQFLRHVERTKLLVHVVDVSGVEGRDAVEDFDTINSELQKYNQVLSTRPQIVAANKMDIPGAEENYKAFKEELEKRGYKVFGISAATNKGLKELLYAVSETLKTLPDTILLDETQNEEVVYKVQEEKPFEIHIEDGVYVIEGKWLRKVLGSTNITNYESLQYFQRALKKKGVITALEEMGIQEGDTVRIYDTEFDYTR
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO1_MAIZE
Sequence: MAVTITWVKARQIFDSRGNPTVEVDVGLSDGSYARGAVPSGASTGIYEALELRDGGSDYLGKGVLKAVSNVNNIIGPAIVGKDPTEQVEIDNFMVQQLDGTSNEWGWCKQKLGANAILAVSLAVCKAGAMVKKIPLYQHIANLAGNKTLVLPVPAFNVINGGSHAGNKLAMQEFMILPTGASSFKEAMKMGVEVYHNLKSIIKKKYGQDATNVGDEGGFAPNIQENKEGLELLKAAIEKAGYTGKVVIGMDVAASEFFGEKDKTYDLNFKEENNDGSNKISGDSLKDLYKSFVSEYPIESIEDPFDQDDWSTYAKLTDEIGQKVQIVGDDLLVTNPTRVAKAINEKTCNALLLKVNQIGSVTESIEAVRMSKRAGWGVMASHRSGETEDTFIADLSVGLSTGQIKTGAPCRSERLAKYNQLLRIEEELGDAAVYAGAKFRAPVEPY
What are the official names of this protein?
Enolase 1, 2-phospho-D-glycerate hydro-lyase 1, 2-phosphoglycerate dehydratase 1.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_SYNS3
Sequence: MSRYVFTSESVTEGHPDKICDQVSDAVLDALLAQDSTSRVACETVVNTGLCMITGEVTSKAQVDFIHLVRDVIRDIGYSGARAGGFDATSCAVLVALDQQSPDIAQGVDEADDHAGDPLDKVGAGDQGIMFGYACNETPELMPLPISLAHRLARRLAEVRHNGTLDYLLPDGKTQVSVVYENDKPVEIDTILISTQHTAEVTGLTDEQEVRNRISEDLWTHVVLPATADLPLKPDRANCRYLVNPTGKFVVGGPQGDAGLTGRKIIVDTYGGYARHGGGAFSGKDPTKVDRSAAYAARYVAKALVAAGLANRAEVQLSYAIGVAKPVSILVESFGSGKVSNAELTDLVQEHFDLRPGAIIEQFKLREMPSLNGGRFYRDTAAYGHFGRPDLNLPWEDVGDKAASLKQAEANRIQSGSSL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_THEFY
Sequence: MIAFLSGRVVSRGAETAVIDVGGVGMTVHCTPAALARLRVGEEATVATALVVREDSLTLFGFADDDERDTFERLQTASGVGPRLALAMLSVHTPDALRRAIATEDTAALTRVPGIGKKGAQRIVLELKGKLGEPGGDTAATPEQSAAAAPRNWRAQVVSGLVNLGWSTREAEAAADAVAAEAGEQPDVAALLRSALRRLSRA
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: O166_CONST
Sequence: MKLTCVVIVAVLLLTACQLLTADDSRGTQKHRALRSDTKLSMSTRCKGKGAPCRKTMYDCCSGSCGRRGKCG
What is the function of this protein?
Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels (Cav).  This toxin blocks N-, P- and Q-type calcium channels (By similarity).
What are the official names of this protein?
Omega-conotoxin-like S6.6.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: EX7S_NOSS1
Sequence: MVKRKNSDNSDTVAHGNYEAKVAEIEAIISRIESGELELEAVFEQFANAVEYLRQCDTFLQQRQQQMDLLIETLNDEDNSEL
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RTCA_SULIA
Sequence: MIEIDGSFGEGGGQILRTSLTLSVITGKPFRIFNIRANRPNPGLQRQHLWAVKAMKMISNAETKGDEVGSKELIFVPHEIKGNINIDIDVGTAGSVTLIIQTVLPAIINKNVRIRIKGGTDVPKSPTIDYIRLVYLEILRKIGIEAKLNLIKRGHYPEGGGEVIIENVNGNPSAFSLLELGKLTIIKGISHVSSLPAHIAERQMNSARELLSKLGVPIEIQTDVRQGEVSKGSGIALAAIGEKSIIGADSLGERGKRAEIVGEEAARILIDNLNTKASVDIHMSDMLMIFASLYGGEYIGAELTSHAYTNMEIIKKFLDIKIDVSGKRPFRFKAKIF
What is the function of this protein?
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA.  The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product.  The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
What are the official names of this protein?
RNA 3'-terminal phosphate cyclase, RNA cyclase, RNA-3'-phosphate cyclase.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLIE_RHIME
Sequence: MIDAIQSVGAFSTIRETEGAGPAPSASLVMPGAGTAAPQAGSFAEVLGNMTTDAIRSMKSAEGTSLQAIRGEANTREVVDAVMSAEQSLQTAIAIRDKVVTAYLEIARMQI
What are the official names of this protein?
Flagellar hook-basal body complex protein FliE.
What is the protein family that this protein belongs to?
Belongs to the FliE family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: PLA2A_ARATH
Sequence: MAAPIILFSFLLFFSVSVSALNVGVQLIHPSISLTKECSRKCESEFCSVPPFLRYGKYCGLLYSGCPGERPCDGLDSCCMKHDACVQSKNNDYLSQECSQKFINCMNNFSQKKQPTFKGNKCDADEVIDVISIVMEAALIAGKVLKKP
What is the function of this protein?
PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.  Releases lysophospholipids (LPLs) and free fatty acids (FFAs) from membrane phospholipids in response to hormones and other external stimuli.  Modulates the trafficking of PIN proteins to the plasma membrane (PubMed:16140037, PubMed:20525850).  Negatively regulates MYB30 transcriptional activity and hypersensitive response control (PubMed:20696912).
What are the official names of this protein?
Phospholipase A2-alpha, Secretory phospholipase A2-alpha, AtsPLA2-alpha.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family.
What are the subcellular locations of this protein?
Secreted. Golgi apparatus. Cytoplasmic vesicle. Nucleus. Note=Relocalization from cytoplasmic vesicles to nucleus is MYB30- mediated.
Protein: Y559A_HAEIN
Sequence: MKSYLKTLIFFPLILQIVVTALLIWFDDDSSGVIVPFSSYALTAFLLAAIPAFLTALLAAKFRYTRYNIASIVLVSSIISFVYCNMASYFYLLLLGEQDTSFWGWLTEGGLSLGL
What are the official names of this protein?
Uncharacterized protein HI_0559.1.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RHN2B_XENLA
Sequence: MTDALLPANLNAKRLSEQNYFRKGKSIAQTGRSKLQNQRAILNQQILKAMRMRAGAENLLRATANNKIREQVLLELSFVNSNLQRLKEELERLNISVEVYQHTEQASNIPLIPLGLKETKDVDFTTAFKDFILEHYSEDASEYENELADLMDLRQACRTPSRDEAGVELLVSYFQQLGYLENRFFPPSRNIGILFTWYDSFTGVPVSQPNISLEKASILFNIAALYSQIGTRCNRQTKIGLEEAVTTFQKAAGVLNYLKETFTHTPSYDMSPAMLGALIKMLLAEAHECYFEKMILSGIQNEFCTLLKAAQEAAKVSEVHMQVYTLMNQAPIKENVPYSWSVMVQVKAEHYKALANYFVAITLIDYQLNLSDDEDKQEKAISQLYDSMPEGLTAQTILKDQQQRTLLGKAHLSKAIRSHEEAIRFSTLCSTLRQIDVLQLILSAFHQRSLLKFSQHQKPDDFLDLLSAPDIVSKTEYQAETIPPQLSKDKVTDIFQRLGPLSIFSVKQRWSAPRKMCITKEDGDFGFVLKGDCPVQVISLDPLCPAATEGLKEGDYIVSVAGKDCKWCSTSQVMDMLQETGQDSIEIQVISIQDQTNSLANKSATYYAGMQKTYSLVCLTMDNDKNTKTQKATKKLSFLSWGFKNRQKAASTICLPSEVKGKPKTDMVFSFPDNSLSTESALY
What is the function of this protein?
Binds specifically to GTP-Rho.
What are the official names of this protein?
Rhophilin-2-B, GTP-Rho-binding protein 2-B.
What is the protein family that this protein belongs to?
Belongs to the RHPN family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region.
Protein: SOM2_HUMAN
Sequence: MAAGSRTSLLLAFGLLCLSWLQEGSAFPTIPLSRLFDNAMLRARRLYQLAYDTYQEFEEAYILKEQKYSFLQNPQTSLCFSESIPTPSNRVKTQQKSNLELLRISLLLIQSWLEPVQLLRSVFANSLVYGASDSNVYRHLKDLEEGIQTLMWRLEDGSPRTGQIFNQSYSKFDTKSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF
What is the function of this protein?
Plays an important role in growth control.  Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1.  It stimulates both the differentiation and proliferation of myoblasts.  It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
What are the official names of this protein?
Growth hormone variant, GH-V, Growth hormone 2, Placenta-specific growth hormone.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: NU2C2_OENBI
Sequence: MIWHVQNENLILDSTRIFMKAFHLPLFDGSFIFPEGILIFGLILLLMIDSTSDQTDIPWFYFISSISLVMSITALLFRWREEPRILFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDLITIFVAPECFSLCSYLLSGYTKKDVRSNEATMKYLLMGGASSSILVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGIGFKLSPAPSHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHPLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDANGGYASMITYMLFYISMNLGTFACIVLFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGLPPLAGFFGKLHLFWCGWQAGLYFLVSIGLFTSVVSIYYYLKIIKLLMTGRKQEITPHVRNYRRSPLRSNNSIELSMIVCVIASTIPGISMNPIIAIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 B, chloroplastic, NAD(P)H dehydrogenase, subunit 2 B, NADH-plastoquinone oxidoreductase subunit 2 B.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: MNME_STAA1
Sequence: MDLDTITSISTPMGEGAIGIVRLSGPQAVEIADKLYKGKHLLNDVPSHTINYGHIIDPESKEVVEEVMVSVLRAPKTFTREDIIEINCHGGILTINRVLELTMTYGARMAEPGEFTKRAFLNGRIDLSQAEAVMDFIRSKTDRASKVAMNQIEGRLSDLIKKQRQSILEILAQVEVNIDYPEYDDVEDATTEFLLEQSKEIKQEINRLLDTGAQGKIMREGLSTVIVGKPNVGKSSMLNNLIQDNKAIVTEVAGTTRDVLEEYVNVRSVPLRLVDTAGIRETEDIVEKIGVERSRKALSQADLILFVLNNNEALTQEDYTLYEVVKNEDVIVIVNKMDLEQNIDINEVKDMIGDTPLIQTSMLKQEGIDELEIQIRDLFFGGEVQNQDMTYVSNSRHISLLKQARQTIQDAIDAAESGVPMDMVQIDLTRTWEILGEIIGETASDELIDQLFSQFCLGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIN9_DANRE
Sequence: MAELEQLLDESSSAKALVSLREGSLSNTLNEKNNLPKSQTTRGRSSYVSMETPTRSSKRSRLSCEDEERPIASRSPRRSQRVTTMPQKLTNVATPDKRVSQKIGLRLRNLLKLPKAHKWCIYEWFYSNIDRPLFEGDNDFCLCLKESFPNLKTRKLTRVEWGTIRRLMGKPRRCSSAFFAEERMALKQKRQKMRLLQQRKITDMSLCKDLPDEIPLPLVIGTKVTARLRGVHDGLFTGQIDAVDTSAATYRVTFDRNGLGTHTVPDYEVLSNEPHETMPISAFAQKQRPPRFQNFLTPPRGSYTGSTQSILMDNDPLFSQSPWRSKLTGTDGETLGGFPVKFLVQVTRLSKILMIKKEHIKHLKEMNTEAEKLKSYSMPIGLDLQKRYATTVLDLEQLNKDLNKVLHEVQQFCFELAPDQGMQPADQPSELRRRCEEESQDVLRQNNTLASGEPRVQNTELTQLISRLTALLLQIRCLAEGGDLNSFEFKSLTDSLNDIKSSIDDSNLSCFQDNVEIHVAHIQSGLSQLGNLHAFSANNTNRT
What are the official names of this protein?
Protein lin-9 homolog.
What is the protein family that this protein belongs to?
Belongs to the lin-9 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL20_STRPM
Sequence: MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYYYAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVADAAAFTALADAAKAKLGK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: CY551_PSEAE
Sequence: MKPYALLSLLATGTLLAQGAWAEDPEVLFKNKGCVACHAIDTKMVGPAYKDVAAKFAGQAGAEAELAQRIKNGSQGVWGPIPMPPNAVSDDEAQTLAKWVLSQK
What is the function of this protein?
Electron donor for cytochrome cd1 in nitrite and nitrate respiration.
What are the official names of this protein?
Cytochrome c-551, Cytochrome C8, Cytochrome c551.
What are the subcellular locations of this protein?
Periplasm.
Protein: RL10_CHLL2
Sequence: MKRDKKEQVVQEVAEKIGRSQGIYLTEYQGLNVAKMAELRNEFRKAGIEYKVVKNTLVKQALLQLAQADKLADGLKSTTAVAFGYDDPIAPAKIIRKFSKTNEALKFKMAAIDGIVYGDDKLVMLSEMLSKTENIGRTAGLINNVVSSVPMVVNAVMRNLVSVLDQVAKQKQ
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: RLME_ACISJ
Sequence: MKAQTKSKKVNKAWLHDHVNDTYVKLAQKEGYRARAAYKLKEIDEQLGLIKPGHVVVDLGSSPGAWSQYVRRRLSPDGAAVGQLNGVIIALDILPMEPIEGVTFLQGDFREEEVLAGLQEAVQARPVDVVVSDMAPNLSGVESVDAVRIAHLIELAVDFAVHHLKPEGALVVKLFHGSGYSQLVQLFKDTFRVVKPMKPKASRDKSSETFLVGMGLKRQG
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.