PharMolix/UniProtQA huggingface dataset:
Protein: CYOB_ECOLI
Sequence: MFGKLSLDAVPFHEPIVMVTIAGIILGGLALVGLITYFGKWTYLWKEWLTSVDHKRLGIMYIIVAIVMLLRGFADAIMMRSQQALASAGEAGFLPPHHYDQIFTAHGVIMIFFVAMPFVIGLMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVNVSLGVGEFAQTGWLAYPPLSGIEYSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMRAPGMTMFKMPVFTWASLCANVLIIASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYINLIWAWGHPEVYILILPVFGVFSEIAATFSRKRLFGYTSLVWATVCITVLSFIVWLHHFFTMGAGANVNAFFGITTMIIAIPTGVKIFNWLFTMYQGRIVFHSAMLWTIGFIVTFSVGGMTGVLLAVPGADFVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKAFGFKLNETWGKRAFWFWIIGFFVAFMPLYALGFMGMTRRLSQQIDPQFHTMLMIAASGAVLIALGILCLVIQMYVSIRDRDQNRDLTGDPWGGRTLEWATSSPPPFYNFAVVPHVHERDAFWEMKEKGEAYKKPDHYEEIHMPKNSGAGIVIAAFSTIFGFAMIWHIWWLAIVGFAGMIITWIVKSFDEDVDYYVPVAEIEKLENQHFDEITKAGLKNGN
What is the function of this protein?
Cytochrome bo(3) ubiquinol oxidase is the terminal enzyme in the aerobic respiratory chain of E. coli that predominates when cells are grown at high aeration.  Catalyzes the four-electron reduction of O2 to water, using a ubiquinol as a membrane soluble electron donor for molecular oxygen reduction; ubiquinol-8 is the natural substrate for E. coli.  Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron and generating a proton motive force.  All the redox centers of this enzyme complex are located within the largest subunit, subunit I.  Protons are probably pumped via D- and K- channels found in this subunit (PubMed:11017202).
What are the official names of this protein?
Cytochrome bo(3) ubiquinol oxidase subunit 1, cyt bo(3) subunit 1, Cytochrome b562-o complex subunit I, Cytochrome o ubiquinol oxidase subunit 1, Cytochrome o subunit 1, Oxidase bo(3) subunit 1, Ubiquinol oxidase chain A, Ubiquinol oxidase polypeptide I, Ubiquinol oxidase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: COAD_JANMA
Sequence: MVTAIYPGTFDPLTRGHEDLVRRASGLFDKLIVGVADSRNKKPFFSLEERLTISNEVLGHYPNVHVESFSGLLKDFVRRHDARVIVRGLRAVSDFEYEFQMAGMNRYLLPDVETLFLTPSDQYQFISGTIVREIATLGGDVSKFVFPSVDKWLKEKIAAQG
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FL3H1_CROXC
Sequence: MAPGATATPFLPTVSNETTLRESFVRDEDERPKVAYNVFSSEIPVISLEGIDEIEGRRVEICKKIVAACEDWGVFQVVDHGVDAGVIADMTRLAREFFSLPPEDKLRFDMSGGKKGGFIVSSHLQGEAVQDWREIVTYFSYPIRARDYSRWPDKPEDWRSVTEKYSETLMELACKLLGVLSEAMGLDTEAITKACIDMDQKVVVNFYPKCPQPDLTLGLKRHTDPGTITLLLQDQVGGLQATKDGGKTWITVQPVEGAFVVNLGDHGHFLSNGRFKNADHQAVVNSNTSRLSIATFQNPAPDAIVYPLAIREGEKPVLDEPITFAEMYRRKMSRDLELAKIKKLAKVENQEVLEKTKVEAVAQPKGLGEILA
What is the function of this protein?
Catalyzes the 3-beta-hydroxylation of (2S)-flavanones to 2R,3R-dihydroflavonols, which are intermediates in the biosynthesis of flavonols, anthocyanidins, catechins and proanthocyanidins in plants (PubMed:31004005).  Can act on naringenin to produce dihydrokaempferol, and on eriodictyol to produced dihydroquercetin (PubMed:31004005).
What are the official names of this protein?
Flavanone 3-dioxygenase F3H1, Flavanone 3'-hydroxylase 1, CcF3H-1.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: CY128_POSPM
Sequence: MLSLTAHDIPWAAGATLLAWAAYKIGRILLLPYTSPLRGLPGPPASSWLFGNVNELMGTEDFALYSEWLEKYGPTMKLNSWFKIPKLFTIDTRAMNYVLSHSQEYPKPERSRHNLVQILGNGLVVAEGELHRRERRIMNPAFGPAQIRELTEIFVEKSQQLRDIWWNDVAIRGGSARIDIQSGLTKMTLDVIGLAGFNYEFNALNPDGKPNELNAAFEVMFEYLSNLRKSYWLIIRSRFPILRCIPDGYSRRTAAAHKVTRRIGLQLIAEKKAALKQMAQSGEKTAGTALKSRDLLTLLIKANTSPDIPEDQRLSDEDVLAQVPTFLVAGHETTSNATTWCLYALAQRLDVQRKLREELREVPVDNPSMDQLNALPYLDAVIRETMRLYPPVVAGIRIASKDDEIPLAVPYMDAHGRMHDTVRIDKGTTFPIPILGVNMSKALWGEDAREFKPERWESVPEAVQPIPGVWSNLMTFIGGPRACIGYRFSLVEMKALIFTLVRAFEFEMAVPIEDITRKIGLVQRPFVRSEMEKGTQMPLIVKQHVRL
What is the function of this protein?
Cytochrome P450 monooxygenase that is able to use 7-ethoxycoumarin and testosterone as substrates for oxidation.
What are the official names of this protein?
Cytochrome P450 monooxygenase 128.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: HIS2_BORPE
Sequence: MTTPTAGDDILSRIADTLATRRPEAGGDPQSSYVAKLLSKAPDAFLKKIGEEATELVMAAKDGQPDRIISETADLWFHCLVALTHYNLRPEDVLAELARREGLSGLEEKARRPRD
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVD_HALOH
Sequence: MGSETITQGFKRAPHRSLLYALGLDEKELEKPIIGIASSYSEIIPGHKHLDKIAEAVKYGVYSAGGTPVIFSTIGVCDGIAMGHSGMKYSLASREIIADSVETVVRAHQFDGLVLVPNCDKIVPGMLMAAARLDIPAIVVSGGPMLAGDYQGKSLDLHNVFEAVGEVKAGKITEGELENIEKAACPGCGSCAGMFTANSMNCLTEVLGMALPGNGTIPAVYAERIRLAKKSGRQIINLVEKNIKPSDIMTREAFKNAICVDMALGCSTNTALHLPAIAHEAGLDLELDLFNDISRKVPHICSLTPAGIYHIEDLYRVGGIPAVMKELSEKDLIQLDQLTVTGDTVGTNISRVGYIDHKIIRPVSNPYHNQGGLAVLKGNIAPGGSVVKQAAVADSMMVHRGPARVFKGEEEAVDAIINGQISEGDVVVITYEGPRGGPGMREMLTPTSALAGLGLDDKVALITDGRFSGATRGAAIGHVSPEAASGGPIGIIQDGDIIEIDIPAKSLNVDISEEEFEKRMSNFNPELPDISGYLGRYAKHVSSASTGAVLE
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: GGR_METMP
Sequence: MKALNDSYDVVVVGAGPAGSMASYNASKNGAKTLLIEKSQEIGTPVRCAEAVPRLEDFGINPDPSFVKSYIRGGYLIAPNGKKIVVKGGKTDGYVVERKVFDKFLAIRSGQAGTQIAVKSRVTKIEKTDDGYNVFVNYLGDEYIVKSKIVIAADGVESNIAEYAGLKSKKNPKEICSCAEYEMTNVKLLNNEMMEFYFGDICPKGYIWLFPKGDTVNVGIGVIDSKKRAIDYLDEFLTHPLVEGRLDNAVPVEFKVGGDPVGGPIKKTVADNIMVVGDAAGHVSPLTGGGIGLSMDCGLMAGDVAAQSIKAENYSEEFLDLYEKKWKEKYYKLLMNDLKYKNILQKLSDDELNAIANSIPENLEEVDVGKLAIKIVAKAPSLLRHFKELL
What is the function of this protein?
Is involved in the reduction of 2,3-digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids.  Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains.
What are the official names of this protein?
Digeranylgeranylglycerophospholipid reductase, DGGGPL reductase, 2,3-bis-O-geranylgeranylglyceryl phosphate reductase, Geranylgeranyl reductase, GGR.
What is the protein family that this protein belongs to?
Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily.
Protein: RSMH_HAEDU
Sequence: MNETDHKHITVLLHEAVDGLAIKPNGIYIDGTFGRGGHSRLILSRLATNGRLIAIDRDPCAIAEANTISDARFQIIHTAFSAIPEVCESLGLMGKIDGILLDLGVSSPQLDDAERGFSFMRDGPLDMRMDTTKGLSAAEWLAQVSIEDLAWVLKTFGEERFAKRIAQAVVSYNKTNSEKITRTLQLAKIIADAVPFKDKHKHPATRSFQAIRIFINRELDELEKALTNALRVLAPEGRLSIISFHSLEDRMVKQFMKKNSKGEVVPKGLPILEAELNKNIPLNIIGKAIMPSEAEIVANARSRSAVLRIAAKR
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBAD_CHECB
Sequence: MLTEDEKQLIQHVWEKVLGHQEDFGAEALERMFTVYPSTKTYFPHFDLHHDSEQIRHHGKKVVSALGDAVRHMDNLSATLSELSNLHAYNLRVDPVNFKLLSHCFQVVLGAHLGREYTPQVQVAYDKFLAAVSAVLAEKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-D, Alpha-D-globin, Hemoglobin alpha-D chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: HEXD_BOVIN
Sequence: MRLVHLDLKGAPPKVCYLSEIFPLFRALGANGILIEYEDMFPYEGHLRLLRAKHAYSPSEIKEILHLATLNELEVIPLVQTFGHMEFVLKHEALAHLREVARFPNTLNPHKEESLALVTAMIDQVMELHPGARWFHVGCDEVYYLGEGETSRQWLQQEPNSKAKLCLSHMEAVASHMRARYPTTTPLMWDDMLRDIPEDQLSGSRVPQLVEPVLWDYGADLDLHGKALLVEKYRKSGFSWLWAASAFKGATGVNQSLTPIEHHLRNHLQWLQVAGSVPADTLRGIILTGWQRYDHFSVLCELLPVGIPSLAVCLQALLHGDFAENVKARVENFLGISSLEEMSFRR
What is the function of this protein?
Has hexosaminidase activity.  Responsible for the cleavage of the monosaccharides N-acetylglucosamine (GlcNAc) and N-acetylgalactosamine (GalNAc) from cellular substrates.  Has a preference for galactosaminide over glucosaminide substrates.
What are the official names of this protein?
Hexosaminidase D, Beta-N-acetylhexosaminidase, Beta-hexosaminidase D, Hexosaminidase domain-containing protein, N-acetyl-beta-galactosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 20 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Extracellular vesicle.
Protein: CTU1_PICGU
Sequence: MEEKKIRKVTLCDICHQSKAVMKRPKNLQKLCKECFYHVFETEIHNTIVDAQLFKPGDKVAIGASGGKDSTVLASVLKTLNEKYNYGLTLVLLSIDEGIVGYRDDSLATVKRNQIQYEMPLEIISYKDLYNWSMDEIVSCAGIRSSCTYCGVLRRQALDRGAAKLEIDHVVTGHNADDMAETVLMNLLRGDIARLERSCSILTSSEGSPIKRSKPFKYTYQKEIVLYAHYKKLDYFSTECSYAPEAFRGTARELLKALESVRPSCIMDIIYSGEHLVVAHKKKRTTEKYKNKPKKNIETEVNSDGSVNLTKKTDGSRCEKCGYLSSNKICKACVLLAGLEMNRPKVNIENNTAVEGSAKVMKTLEQLSF
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation.  It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.  Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation.  May also be involved in protein urmylation.
What are the official names of this protein?
Cytoplasmic tRNA 2-thiolation protein 1, Cytoplasmic tRNA adenylyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDL_PSEA6
Sequence: MTLANATHTSAIDIARFGKVAVMFGGRSAEREVSLRSGQAVLSALISAGVNAHGFDPAESELHQLVEQKFDRVLIMLHGRGGEDGSLQGALQQMNMPYTGTGVLGSALCMDKIRSKQVWQSLGLPTANYEIADKRDFNAANCSDIMSRLGDLVMVKPAQEGSSIGMAKVSNAQQLAAAIQQAFEYDDKVLLEQFIQGSEYTVSLLNGEAMPSISMSTPRDFYDYEAKYQSNTTEYFCPSGLPAEQEGLLARLALDAFDAVAGSGWGRVDFMQDMLGQFYLLEANTVPGMTEKSLVPLAAKQAGLSFEQLSLAVLATAG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLIE_LEPIN
Sequence: MEINSNSSLWHSYNSGYNGNKPHPLSPKGDQVKVSITEDRHYKDVKQPVSPDYVAESFSEAMKNALTSVNDLQVEADELTQKMVFDPNSVDAHQVMIASEKARVALTFTKTIADGVVRAYRELTSLR
What are the official names of this protein?
Flagellar hook-basal body complex protein FliE.
What is the protein family that this protein belongs to?
Belongs to the FliE family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: CARB_SULAC
Sequence: MRENVKRVLVIGSGPIKIAEAAEFDYSGSQALKALKEEGIETILVNSNVATVQTSRKFADKLYMIPVTWWTVERVIEKERPDAIMIGFGGQTALNVGVDLYKKEILKKYGVKVLGTPIEGIERALSREKFRETMINVNLPVPPSLSARSEEEALEKARQIGYPVMVRVSFNLGGRGSTVAWSEEDLKRDIGRALSQSYIHEVLIEKYLHHWIELEYEVMRDKHGNSAVIACIENLDPMGVHTGESTVIAPCQTLDNKEFQDMRSMSIDVAKSIDLVGECNVQFALNPLAYEYYIIETNPRMSRSSALASKATGYPLAYVSAKLALGYELYEVLNKVSGSTCACFEPSLDYVVIKIPRWDLDKFENVEHSLATEMKSVGEVMSIGRSFEEALQKAVRMLDLGEPGIIGGKVYNSKMTKIDSLRMLKERRPYWFLYASKAFKEGATIDEVYEVTGINKFFLNKIKNLVDFYESIKNNKGLDQKTLSIAKRLGFSDYQIASAVGLSEKDIRELRQKYGIEPKVKQIDTLAGEWPAVTNYLYVTYNGTEDDIEFSNGIRKLLIVGAGGFRIGVSVEFDWGVVSLLDSASKYFDEVTIINYNPETVSTDWDIARKLYFDEISVERILDLVRKEKFNYVATFAGGQIGNTISKKLEENGVKLLGTSGHSVDIAEDREKFSRLLDKLGIKQPDWISARSIEEVRKFVEMVGYPVLVRPSYVLSGSAMRIVYNDTELVSYIKKATEISSEHPVVVSKYIDNAIEAEIDGASDGRGVYGVVLEHVEEAGVHSGDATISIPFKKLSPETVHKMKESIHSISRELNIKGPFNVQFVVKNGTPYIIEMNLRASRSMPFSSKVVGKNIIDLALTGVIKGFDFDEFVELKAKSWGVKSAQFSWAQLKGAYPFLGPEMRSTGEAASLGVDFYDALLKSWLSSSPNRLPDQKGIALVYGRSNVEYLQASARNLSEYGMTVYTLSDAPIYGYEVTSSGKSVELIKDRKVEIVVTDGYLKSLDYEVRRIAVDYNVPIILNGRLGEELTKAFLLRKSNMTFYEIGEYGAGI
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: ATPA_SHIBS
Sequence: MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLADCMQGEMISLPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGAPIDGKGPLDHDGFSAVEAIAPGVIERQSVDQPVQTGYKAVDSMIPIGRGQRELIIGDRQTGKTALAIDAIINQRDSGIKCIYVAIGQKASTISNVVRKLEEHGALANTIVVVATASESAALQYLAPYAGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQYRELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLADVELSKIGSFEAALLAYVDRDHAPLMQEINQTGGYNDEIEGKLKGILDSFKATQSW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ADDA_LACCB
Sequence: MTQFTTSQQAAITHDGHDVLVSASAGSGKTTVLVERIIQKILKQHADITRMLIVTFTRAATAEMRTKIQTALKKALTERRHELSGEDRRHLANQIAMVNAAKISTLDAFSLQIVQTYYYVIDLDPGFRLLTDETERYMLQERVWDDLREQLYASDEAPAFEQLTANFSGDRDDSGLQDLMFELIRQAGATTDPKAYLEGLATPYAPEKWEATFSQQIWPRVKGQLLQIATSLTQASALANQLPNPIWYQQIQADLAPLQTLLETNAPTYDTVRSVLISHEFAAWSRISKGLDDADKDTKNAAKDLRDAAKKTWQNKLAPTFALAAEQIGDLLREAQPLVATLANVALKFEDALTAEKAARHVQDYSDIAHNALRILQQKDPQTGAPIADNYRASFDEVMVDEYQDISPLQEALLAAVSTTTPGDRFMVGDVKQSIYGFRLADPQLFIHKYQTFQDAPTDPAAPERIILAENFRSTKNVLAFTNLIFSQIMDPEVGDLSYDNAAALRYGALDYGDAHPAVKVLLYSKATSDEDSSDASELPGDADDNEPVDIATGQTQLVLAEIQRLINDPDAQLWDRQAQEYRRIHYRDITLLTRQTSQNSLIQTQFAAAGVPLFVADTKNFFKTTELMVMLALLKVIDNQKQDIPLVAVLRSPIVGLSADQLALIRLAAKQVPYYDAVTAFLQAEPKTPLAQRTHDMLTHFFNQLSHFRDLARENDLVTLLWAIYQDTGFLDYVGGTPGGSQRQANLQALIDRARTYEAGGFKGLFAFIHFITLMQKQDQDLAMPAQVDPDNDAVKLMTIHKSKGLEFPVVFLMQANKHFNMRDQTGTAILTKQGIGIKWLDPETRVEYELPQYQAAKAARQNQTLAEEMRLLYVALTRAQQRLYVVGATMSGNQLTSADKTVEKWAAAAEGEARVLAPQVRSGATSYLDWIGPALIRHPQARGLAETTIKPALVGDETEFTIEIDVNPQVTPTATPEKVSDDSGTMVDLSAWFKKAYPFQAATTTTGFQSVSEIKRAFDDPDTIDLVNADRFLGPKPPMRDLTAPAFLTETPSGISPAAIGTATHLLLQLVDLAKPITMASLRALRDQLTTKQVIAVDVAKHIDLTALIRFFETDLGRLLLAKPQQVHREVPFSMLLPADQVFEALADDPGEDVLIHGIIDGYVSDEQGVTLFDYKTDHNPNTAVLVDRYRGQLNLYAQALQDLQPKPVLHRYLVFLRTGTVVDLVASGAGK
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.
What are the official names of this protein?
ATP-dependent helicase/nuclease subunit A, ATP-dependent helicase/nuclease AddA, DNA 3'-5' helicase AddA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddA subfamily.
Protein: TCRGL_HUMAN
Sequence: MQAGARFQRRRRQLQQQQPRRRQPLLWPMDAEPPPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASAPPPAAPLLPGLPGWPAPSEPVLPLLPLPSAPDSAAAAAAHPFPALHGQWLFGGHSPSLGLPPSSTVELVPVFPHLCPSALATPIGKSWIDKRIPNCKIFFNNSFALDSTWIHPEESRFFHGHEKPRLLANQVAVSLSRPAPASRPLPTVVLAPQPIPGGCHNSLKVTSSPAIAIATAAAAAMVSVDPENLRGPSPSSVQPRHFLTLAPIKIPLRTSPVSDTRTERGRVARPPALMLRAQKSRDGDKEDKEPPPMLGGGEDSTARGNRPVASTPVPGSPWCVVWTGDDRVFFFNPTMHLSVWEKPMDLKDRGDLNRIIEDPPHKRKLEAPATDNSDGSSSEDNREDQDVKTKRNRTEGCGSPKPEEAKREDKGTRTPPPQILLPLEERVTHFRDMLLERGVSAFSTWEKELHKIVFDPRYLLLNSEERKQIFEQFVKTRIKEEYKEKKSKLLLAKEEFKKLLEESKVSPRTTFKEFAEKYGRDQRFRLVQKRKDQEHFFNQFILILKKRDKENRLRLRKMR
What are the official names of this protein?
Transcription elongation regulator 1-like protein.
Protein: RL36_CALS4
Sequence: MKVRPSVKKMCEKCKIIKRKGRVMVICENPKHKQKQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: CH60_SHEFN
Sequence: MAAKEVLFGNDARVKMLAGVNILANAVKVTLGPKGRNVVLDKSFGSPMITKDGVSVAKEIELTDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIVVEGLKAVAAGMNPMDLKRGIDKAVIAAVAELKLLSQECSDTKAIAQVGTISANSDESIGDIIATAMEKVGKEGVITVEEGQALENELDVVEGMQFDRGYLSPYFINKPETGSIELDSPFILLVDKKVSNIRELLPILEGLAKTGKPLLIVAEDVEGEALATLVVNNMRGIVKVAAVKAPGFGDRRKAMLQDVAILTGGTVIAEEIGLELEKATLEDLGTAKRVIITKDNTTIIDGSGDQVQISARVSQIKQQVEDSTSDYDKEKLQERMAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALVRVASKIKDVEVLNEDQKHGVVIALRAMEAPLRQIATNAGQEASVVANTVKNGEGNFGYNAGNDTYGDMLEMGILDPTKVTRSALQFAASIAGLMITTEAMIAEVPQDSAPDMGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECO_XANCP
Sequence: MLIEHERGFVLHARAWRETSLLVEVLTEQHGRVGLLARGVHGPRKQALRAALQPLQLIQFTAVQRGELAQLRQAEAIDTAPRLLGEAMLAGFYISELLLRLAPRHAPVPELFDCYAQARAHLASGAALAWGLRQFERDVLDGLGFGFDLQHDSDGQPIDPAARYRLDPQDGARRVLSERLAQDRRETVTGAALLALGEDRVPATEDMPGLRRSMRGVLLHHLSGRGLKSWEMLEELARRGA
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: RRP15_MOUSE
Sequence: MAAAVQDSRVSPGEILKRSPKKKKKMKMVAKAAASKLEDEVKDSSDGEGSCDSEMDHSDDGAAEADSEDNVESCEEDNEDAAESSAGTNSGWADAMAKILNKKTPKSKATILTKNKELEKEKEKLKQERLEKRKQLDKKREWEMLCRVKPDVVKDKEAERNLQRIATRGVVQLFNAVQKHQRNVGEKVKEAGGSVRKRAKLMSTVSKKDFISVLRGMDGTSRNSPAGKSPKARQTEVKSEESPGWKILRDDFMMGASMKDWDKESEGEEPAGGRAEAAASR
What are the official names of this protein?
RRP15-like protein, Ribosomal RNA-processing protein 15.
What is the protein family that this protein belongs to?
Belongs to the RRP15 family.
Protein: RS10_METS5
Sequence: MPNKARIRLWSTNVNNLNYVVNQIKGIVDKTGVSMRGPIPLPTRRMEVPVMRLPHGEGRKKWEKWEMSLHKRIIDISADERVMRQLMRVKVPEDVYIEIQLI
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: CLPC_TRICV
Sequence: MFEKFTEGAIKVIMLSQEEARRMGHNFVGTEQLLLGIIGQRHGIGARALKKQKVTLKKARREIELYIGRGTGFVASEIPFTPRAKRVLEMAVHEGKDLGQNFVGTEHILLALISESDGVAMRTLDKLGVNIPKLRNLILMYIEENQEEILRPLTQAEKFLLEREKKGSSTPTLDEYSENISKEAVDGKLDPVIGRDKEIHEVIKVLARRRKNNPVLIGEPGVGKTAVAEGLAQLIIAEKAPDFLDGNLLMALDLGSILAGTKYRGEFEERIKRIVEEVQNDSAIILVIDEIHTLVGAGAAEGAVDAANILKPALARGKFRCIGATTIDEYRKYIERDPALERRFQPVHVKEPTVGVTIEILLGLRSKFEEHHTLSYHDKAVEQAAILADKFIADRFLPDKAIDVLDEAGSRVRLENRRLPRGMKRLLKELQDTLRDKEESIKEHDFDIAKQLVDHEMEVRTHIRIMKQSILTNETLGLARKEIDTVLEGDVAEVIAGWTGIPVNKISDSESKRLLTMEETLHERLIGQHHAIVSVSKAIRRARVGLRNPDRPIASFIFAGPTGVGKTELTKALSEYMFGNEDSMIRLDMSEYMEKHTVAKLIGSPPGYVGYNEGGQLTEAVQTKPYSVVLLDEVEKAHPDVFNLLLQILDDGRLTDSKGRTIDFRNTMIIMTTNLGAKIIEKESGIKPKTKQDKPAFRIDESGCLGWEPTPEPIKDSALFEKVTELVNEELKEFFRPEFLNRIDEIIVFNHLTKYDIWEICGLMVKQLQKRLEEKELTLEVDVSVRNLLTEEGYDPVYGARPLRRAVMRLLEDTLAQQCLSKPLYPGTILRVSRVKEEGTLASYTNDVKVEIDYRRVDPRLLEQAEEKKEQNQEETKQNILKTDA
What is the function of this protein?
May interact with a ClpP-like protease involved in degradation of denatured proteins in the chloroplast.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpA homolog.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DNLJ_THESK
Sequence: MTLEEARRRVNELRDLIRYHNYLYYVLDAPEISDAEYDRLLRELKELEERFPELKSPDSPTEQVGARPLEATFRPVRHPTRMYSLDNAFSLDEVRAFEERIERALGRKGPFLYTVERKVDGLSVNLYYEEGILVFGATRGDGETGEEVTQNLLTIPTIPRRLTGVPDRLEVRGEVYMPIEAFLRLNQELEEAGERIFKNPRNAAAGSLRQKDPRVTARRGLRATFYALGLGLEETGLKSQHDLLLWLRERGFPVEHGFTRALGAEGVEEVYQAWLKERRKLPFEADGVVVKLDDLALWRELGYTARTPRFALAYKFPAEEKETRLLSVAFQVGRTGRITPVGVLEPVFIEGSEVSRVTLHNESFIEELDVRIGDWVLVHKAGGVIPEVLRVLKERRTGEEKPIIWPENCPECGHALIKEGKVHRCPNPLCPAKRFEAIRHYASRKAMDIQGLGEKLIEKLLEKGLVRDVADLYRLKKEDLVNLERMGEKSAENLLRQIEESKGRGLERLLYALGLPGVGEVLARNLALRFGHMDRLLEAGLEDLLEVEGVGELTARAILNTLKDPEFRDLVRRLKEAGVEMEAKEREGEALKGLTFVITGELSRPREEVKALLRRLGAKVTDSVSRKTSFLVVGENPGSKLEKARALGVPTLSEEELYRLIEERTGKDPRALTA
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: TSG10_MACFA
Sequence: MMRSRSKSPRRPSPTARGANCDVELLKTTTRDREELKCMLEKYERHLAEIQGNVKVLTSERDKTFLLYEQAQEEIARLRREMKSLARKAMDTESELGRQKAENNSLRLLYENTEKDLSDTQRHLAKKKYELQLTQEKIMCLDEKIDNFTRQNIAQREEISILGGTLNDLAKEKECLQACLDKKSENIASLGESLAMKEKTISGMKNIIAEMEQASRQSTEALIMCEQDISRMRRQLDETNDELAQIARERDILAHDNDNLQEQFAKAKQENQALSKKLNDTHNELNDIKQKVQDTNLEVNKLKNILKSEESENRQMMEQLRKANEDAENWENKARQSEADNNTLKLELITAEAEGNRLKEKVDSLSREVEQHLNAERSYKSQISTLHKSVVKMEEELQKVQFEKVSALADLSSTRELCIKLDSSKELLNRQLVAKDQEIEMMENELDSARSEIELLRSQMTNERISMQNLEALLVANRDKEYQSQIALQEKESEIQLLKEHLCLAENKMAIQSRDVAQFRNVVTQLEADLDITKRQLGTERFERERAVQELRRQNYSSNAYHVSSTMKPNTKCHSPERAHHRSPDRGLDRSLEENLCYRDF
What is the function of this protein?
Plays a role in spermatogenesis (By similarity).  When overexpressed, prevents nuclear localization of HIF1A (By similarity).
What are the official names of this protein?
Testis-specific gene 10 protein.
What is the protein family that this protein belongs to?
Belongs to the CEP135/TSGA10 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=In mature spermatozoa, localizes to the centriole and midpiece (By similarity). The 27-kDa peptide associates with the fibrous sheath in mature spermatozoa and localizes to the principal piece of sperm tail, while the 55-kDa peptide localizes to the midpiece. Detected in the cytoplasm of almost all spermatogonial cells within the seminiferous tubules (By similarity).