PharMolix/UniProtQA huggingface dataset:
Protein: EST3_CANGA
Sequence: MPPFIPKSRSNAVESVYLHGWVRDMLLESKTSQNIAVIPRVDPDEASIPLLSRRIYANRRHFVKITKFFQVHNYSVYASVKDSQHQILSQFTPKCVSEFESRNRSRITSDTVNTLFMIGDAKLGIMVVDELRHYFGEKIVSLFNGLDMPYIPYLIINQAFILDYDQVEAFKMTPFVYQYI
What is the function of this protein?
Component of the telomerase complex involved in telomere replication.  Stimulates RNA/DNA heteroduplex unwinding which favors the telomere replication by the telomerase (By similarity).
What are the official names of this protein?
Telomere replication protein EST3.
What is the protein family that this protein belongs to?
Belongs to the EST3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: SYC_FRAP2
Sequence: MIFYNSLSGKKEEFKPIEPNKIKMYVCGITVYDDCHIGHARTNIAFDVINRYFKYRGFDVTFVRNITDIDDKIIKRANENGETTDKLVERTIKSMHDAFDKLNILRPTKEPRATQTIPEMIAMIETLVEKGFAYQGTNGDVFYRVAKFADYGKLSKQNLEALEQGSRVDVVEEKENPMDFVLWKMAKEGEPAWDSPWGAGRPGWHIECSAMSKKLLGDTFDIHAGGSDLRFPHHENEIAQSEACNECTFANYWLHSGMVKVNAEKMSKSLNNFFTINEVIEEYHPEVIRYFLASTVYRSEINYSKENLDNARASVERLFNALRDIEPVEVNLPDDASEYEEKFIKAMDNDFNTPEALAVLFSLAKEINTLKTVNKYKASGYAFLLRKLCDVLGILFTDIEEYFKQGDGIDVSEIEKLIAERTQAKKDKNYARADEIRNDLQNQGIILEDSATGTTWKKG
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPP_MYCBP
Sequence: MQVHVVDHPLAAARLTTLRDERTDNAGFRAALRELTLLLIYEATRDAPCEPVPIRTPLAETVGSRLTKPPLLVPVLRAGLGMVDEAHAALPEAHVGFVGVARDEQTHQPVPYLDSLPDDLTDVPVMVLDPMVATGGSMTHTLGLLISRGAADITVLCVVAAPEGIAALQKAAPNVRLFTAAIDEGLNEVAYIVPGLGDAGDRQFGPR
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: VKT1_ANESU
Sequence: INKDCLLPMDVGRCRASHPRYYYNSSSKRCEKFIYGGCRGNANNFHTLEECEKVCGVR
What is the function of this protein?
Dual-function toxin that inhibits both the serine protease trypsin (Kd<30 nM) and voltage-gated potassium channels Kv1. 2/KCNA2 (IC(50)=2800 nM).
What are the official names of this protein?
KappaPI-actitoxin-Avd3b, KappaPI-AITX-Avd3b, Kunitz-type serine protease inhibitor kalicludine-1, AsKC1.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family. Sea anemone type 2 potassium channel toxin subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: SPRT_PSE14
Sequence: MPDQLNSRVETCYQQAETFFKRTFKRPMVSFQLRGQKAGVAHLHENLLRFNPQLYKENAEDFLRQTVPHEVAHLIAHQLFGGSIQPHGEEWQLIMRGVYELPPNRCHTYAVKRRSVIRYIYRCPCPDSDFPFTAQRHSMVRKGRRYLCRRCREPLVFSGETRTE
What are the official names of this protein?
Protein SprT.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAPSN_MOUSE
Sequence: MGQDQTKQQIEKGLQLYQSNQTEKALQVWMKVLEKGSDLVGRFRVLGCLVTAHSEMGRYKEMLKFAVVQIDTARGLEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQLGGQVSLSMGNAFLGLSLFQKALESFEKALRYAHNNDDTMLECRVCCSLGSFYAQVKDYEKALFFPCKAAELVNDYGKGWSLKYRAMSQYHMAVAYRLLGHLGSAMECCEESMKIALQHGDRPLQALCLLCFADIHRSRGDLETAFPRYDSAMSIMTEIGNRLGQVHVLLGVAKCWMARKVQDKALDAIEKAQDLAEEVGNKLSQLKLHCLSESIYRSKGLQRELRTHVVRFHECVEETELYCGLCGESIGERNSRLQALPCSHIFHLRCLQNNGTRSCPNCRRSSMKPGFV
What is the function of this protein?
Postsynaptic protein required for clustering of nicotinic acetylcholine receptors (nAChRs) at the neuromuscular junction.  It may link the receptor to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin (By similarity).
What are the official names of this protein?
43 kDa receptor-associated protein of the synapse, RAPsyn, 43 kDa postsynaptic protein, Acetylcholine receptor-associated 43 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the RAPsyn family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Postsynaptic cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Note=Cytoplasmic surface of postsynaptic membranes.
Protein: UNG_BACVZ
Sequence: MKQLLKDSWWNQLKDEFDKPYYQELREMLKQEYSSQTIYPDSHDIFNALHYTPYEDVKAVILGQDPYHGPGQAHGLSFSVQPGVRQPPSLKNIFIELQDDIGCSVPNHGSLVSWAKQGVLLLNTVLTVRRGQANSHKGKGWERLTDRIIDVVNEREKPIVFILWGRHAQMKKERIDTSKHIIIESTHPSPFSARNGFFGSRPFSRTNAALEKMGEQPIDWCIPDLPQ
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_MYCVP
Sequence: MRIVLLGPPGAGKGTQAQKLAEKLGIPQISTGDLFRYNISNGTELGLEAKKYLDAGDLVPATLTNALVDDRLDDEDAAAGFILDGYPRSVEQAKALDEMLKKRDLSLDAVLEFRVPEEELVSRLKGRGRDDDTEDVIRNRFRVYRDETAPLLDYYSADLKTVDAVGELDEVFARALKALGR
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_GRAFK
Sequence: MATEGNNLSQYDKNTIPNAKDFRFGIVVSEWNEEITEGLFQGAFDAWIENGVQKENIVRWNVPGSFELIYGCKKMQQSFEMLDAIVAVGNVIQGETKHFDFVCDGVTQGIKDLNVQTDIPVIFCVLTDNNIEQSRARSGGKHGNKGTEAAIAAIKMAQLRKDAKFYKG
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: RTC5_SCHPO
Sequence: MGQKESQFKVLWQLQTHEEYMKQTSSFLRDFNALERYNLKENFEALSSFDNGEKIWVEDAFTTFFGIPDVIQLSPFFYRSACSFGRDLNINRQRLTFSALARFLASYTGRHKDVWSDFESNLMIIASWCDSFPKFRVEVLKNSKQISRLIHSDVQNISNFFDQNFGIRRSNIYQLCLLLLCISKLKPGESVGCHINSFLDSMFVKEQKAAFYVLQGISPDISSNIIKPSYLLHFLESNPYFLKSLGSLFELALFPHSAHNQKVQDDVSPLNDFAILSPLIHAQICFFLPKSVWQVNGLTSLFRASFHGYSMYALERKMCNYHNPSILLIKAKKINANHKSSSRPISLDATIPRKYPPHCIGTDKAVPQKFGADFHNENILLGAYISTRWRQSHMGFFGDHSTLLFQLQPIHQVYYASNLDKNYCMFDKNVGLGFGLSRHKVTNKVQYDVPGVCMYIDDGLEYGLFRHAGDGAFKPATNYENFEYEERFLIQDLEVIGVDTTKPVEPIHIGL
What is the function of this protein?
May be involved in a process influencing telomere capping.
What are the official names of this protein?
Restriction of telomere capping protein 5.
What is the protein family that this protein belongs to?
Belongs to the RTC5 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: THSB_ARCFU
Sequence: MATLQGQPVLILREGTQRTVGRDAQRMNIMAARVIAEAVRSTLGPKGMDKMLVDSLGDVVITNDGVTILKEIDVEHPAAKMIIEVAKTQDNEVGDGTTTAVVLAGELLKRAEELLDQEIHPAIIANGYRYAAEKALEILNEIAIPISKDDDEILKKIATTAMTGKGAEVAIDKLAEIAVNAVKMIAEESNGQVEVNTDYIKIEKRQGGSIEETELVDGIVLDKEVVHPGMPKRVENAKILLLDSALEVKETEIDAKIRITDPEKLQKFIEQEEAMLKEMVDKIVNAGANVVFCQKGIDDLAQYYLAKAGVLAVRRVKKSDMEKLAKATGAKVLTDLRDISSEDLGEAALVEERKVGDEKMVFVTGCKNPKAVTILVRGGTEHVVEEIARGIEDAVRAVACAVEDGKVVVGAGAPEIEVSLKLREWAPSLGGREQLAVEAFATALEIIPRTLAENAGLDPIDVLVELKAAHEKGQKYAGVDVDTGKVVDMKERGVFEPLRVKTQAIGSATEVAVMILRIDDIIAAKGLEKEKGGGGEGGMPEMPEF
What is the function of this protein?
Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity.
What are the official names of this protein?
Thermosome subunit beta, Chaperonin subunit beta, Thermosome subunit 2.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
Protein: MUTS_ACIBY
Sequence: MNSAEIMADLSNHTPMMQQYLKVKKDYQHALLFYRMGDFYELFFEDAHLAAKLLGITLTHRGKANGNPIPMAGVPYHSAEGYLARLVKAGRTVAICEQVGEVTGKGPVERKVVRILTPGTLTDDALLTSYQSSNLVALCIHQNQIGFALLDLSAGIFKVQQQDYKPEQLPIELARLMPSEILIDEDLVDPNIIEQIKKHLDCPVTKRPNVDFNLNNAQKTLCDQFSVSTLSGFGLDPLPLAKAAAAALIHYAKETQKTALPHIRSILLEQSSDFIALDPITRRNLEIIEPLFEHGTSLFQLVNDCQTAMGGRLLSRTLMQPVRDTALLDARLDAIEQLIQGYHESPVRLVLKEIGDIERVLSRVALGSARPRDLVQLRHACAQIPFLRNALAPVVQAKKSKLLGQLDQELGDFKSLHQHLMAAIVENPPVLLRDGNVIAEGYDAELDELRQIRDHAGQFLIDLEIKERERTGISTLKIGYNRVSGYYIELTRAQAEQAPADYIRRQTLKNAERYITPELKSFEDKVLSSESRALAREKALFEALLENLRENIAHLQMMSSAIAQIDVIANFAHQARLNNWARPEFTPETGIKIQGGRHPVVEALSKAPFTPNDTFLDVQHRMAIITGPNMGGKSTFMRQTALISLLAYCGSYVPARAAKLGPIDRIFTRIGSADDLSTGKSTFMVEMTETSQILHHATNQSLVLMDEVGRGTSTYDGLSLAWACVVDLTKRVKCLCLFATHYFELTELGSEPGIDNYHVTAQELNGNLILLHKVQQGPASQSHGLQVAKLAGIPANVIKEAQKRLRILEKQQQQHLQTSVQSDLFATLDSEVTPSTQVIEKVIEVEVSSPALDLLKQIEVDNLTPRQALEQLYELKAALNS
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: NADK_DESVM
Sequence: MHTALRSILIVTKSGHREAEALGERMRAWLAARGLSARVVENTGDAVSLAVAGQECSLALVLGGDGTILGVARRLLGSGVPLLGVNLGKVGFLAEVAATRWESSLERLLSGGVTVQERLALSFRVERDGATVHSGGAVNDVVINRGILARVINLDLRVGSERLGELRADGLIVSTPTGATGYSVSARGPLVHPQLHVYTVTPICPFLNNLLPLVLPGEARLSVTVRDRTNEVYLTQDGQEGYALQAGDVVHVERAPGGMLFATIEELSYYRKLKAKGFIKDQA
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOB_HALHL
Sequence: MGVEGILERGYVTTSADKLINWARTGSLWPMTFGLACCAVEMMHTAAGRYDMDRNGLIFRPSPRQSDVMIVAGTLCNKMAPALRKVYDQMPEPKWVISMGSCANGGGYYHYSYSVTRGCDRIVPVDIYVPGCPPTAEALYYGILQLQNKIRRTNTIAR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ATPE_THISH
Sequence: MAMTFHVDIVSAEESIYSGTAQMVVAPAEGGEVGILPRHSQYIAQLKPGEVRVKVSDSGEEHSIFISGGLLEVQPHVVTVLADTAVRAKDLDEAEAKEAMRRAEEALSDRKADFDYAKAQAELIEAAARLRMIEKLRRHTR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RNPA_BORAP
Sequence: MKKRNISLKSKIEIQKIFKEGNLIRFSNLNLKMFCKSNHLIYSRLLVTFSKSFRGSVKRNRVRRLFKEAFRKRLELLEGRAIDIIFVVYYDRLDLTYFSIESLMKSLVLMV
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: LCMT1_CAEEL
Sequence: MDSEAVSSDSHVAAAIATRRRSNSVSDDYSVQRTNDDATQCKYFATQKGYWKDEFISRFANSSSNVSEARRFPEISMGYWARTAAIEKYVRDFLNEFDGNAQVVSLGCGFDTLFWRLVSSGAKLVKYVEVDFSSVTSKKIRHILKPIGPNSVDLKKSFESDAVVSHHADLHAGNYHLIGADLRQANELDQKLATCQLSHDIPTIFIAECVLVYMSADSSTALLKQIVSQFKQPAFVNYEQFRTSDAFTKVMEQNLGDRGIQLHGLEMCESAEKQEERFRNAGFKEVKVMDMNQIFNNFLDQKEVSRIREIEMLDEMELLQQLFAHYCVVSARI
What is the function of this protein?
Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.
What are the official names of this protein?
Leucine carboxyl methyltransferase 1, [Phosphatase 2A protein]-leucine-carboxy methyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. LCMT family.
Protein: SECA_HALOH
Sequence: MLKFIKNIFKDSNTRELEKLQHIVDEINSLEPYMKKLSDEQLRDKTREFKERIVKGETLDELLPEAFAVVREAAQRSTSEKFRHYDVQLMGGIVLHQGKIAEMKTGEGKTLAATLPVYLNALTGKGVHVVTVNDYLAKRDSEWMGQIYRFLGLSVGVILNGMTPRERKKAYQADVTYGSNNEFGFDYLRDNLAYNPDDVVQGELHYAILDEVDSILIDEARTPLIISGPAQETTKDYRKFNRIIPRLVKGRDYEVDEKNRTVHLTEEGLARVEKKLNISNLYDDQNFQLAHQLNQALKAHTLMKKDRDYIVKDGEVKIVDEFTGRIMEGRRFSEGLHQAIEAKEGVAVNKESQTFASITYQNFFRMYDKLAGMTGTAATEEEEFIKIYGMEVVQIPTNKPMIREDLPDVVFRTEEAKFKAVAEEVALKYKKGQPVLVGTVDIEKSEKLSRMLKRKGIPHQVLNAKNHEKEAEIIKKAGQKNSVTISTNMAGRGTDIVLGEGVKELGGLHVIGTERHESRRIDNQLRGRSGRQGDPGSSQFFVSLEDDLLRLFGSDNISMLMDRMGFDDDQPIEHKMITRSLERAQKKVEGRNFEIRKTILEYDNIMNKQREIIYEQRKKILFASDLKEYIMGMIEMLVDDIMDTYLSSEVHPDDWDIDGLIKYLSEFNLVNINEEDFKDKDREKIREELIKIATKTYEEKEAEIGKESMQKLIKNLALRIIDRNWMNHLDNMDELRQGIGLRAYGQRDPLTEYKFESYDMFNGMTGTIREEIIKNLFRIEVKEREINLDPIMLKRLKYRRNFLSNRANRPQKKAKRQPIVKPDKPGRNDPCPCGSGKKYKHCCGR
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: FLBY_CAUVC
Sequence: MAIAAVDANDRVHQLILLTERLTDLIAKQAVAFETHRPHQAAQYVEETSKLANLYRHESMRVRANVGLVESARLELRQRLMRATEAFDAVLARQSRAVEAAKIVTEGLVHAIAQEVASQRAAPATTYGAGGMVNDRPQHGAAITLNRKA
What are the official names of this protein?
Flagellar basal-body protein FlbY.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: H3_NEUCR
Sequence: MARTKQTARKSTGGKAPRKQLASKAARKSAPSTGGVKKPHRYKPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKSDLRFQSSAIGALQESVESYLVSLFEDTNLCAIHAKRVTIQSKDIQLARRLRGERN
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: FABV_PSEPW
Sequence: MAIIHPKVRGFICTTTHPKGCELNVRDQIEATRKLGVREDGPKKVLVIGASSGYGLAARITAAFGFKADTLGVFFEKPGTETKAGTAGWYNAAAFDKFAKAEGLYSKSINGDAFSDEARAKVIELIKNEMGGQVDLVIYSLASPVRKLPQTGEVIRSALKPIGQPYKSTAIDTNKDTIIEASIEPATEQEIADTVTVMGGQDWELWIDALNAAGVLAPQARTVAFSYIGSDITWPIYWHGALGKAKQDLDETAQRLAGKVGGSANVAVLKSVVTQASSAIPVMPLYLSMVFKIMQEKGVHEGTQDQLDRMFRDRMYRADGSPAELDEKGRLRLDDWELRDDVQGACKALWPQVTTENLFELTDYAGYKKQFLNLFGFERADVNYDEDVATEVKFDCVEL
What is the function of this protein?
Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II).  Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH], ENR.
What is the protein family that this protein belongs to?
Belongs to the TER reductase family.
Protein: SYH_ACIET
Sequence: MQKLVAIKGMNDILPPDSARWEWLEDKVRTLMARYAYRNIRTPIVEPTPLFVRGLGEVTDIVEKEMYSFEDRLNGEQLTLRPEATAGVVRAVVEHSMLYDGGKRLYYMGPMFRHERPQRGRYRQFHQIGAEALGFPGAEADAEIILLAHALWAELGLENVRLELNSLGQPDERRAHRAALIAYLEQHMDVLDEDARRRLHSNPLRILDTKNPAMQALVEGAPRLIDFLGEASLQHFETVKAILDANGVAWSLNPRLVRGMDYYNLTVFEFVTDQLGSQGTICGGGRYDYLIEQIGGKFAPAVGWALGVERVLELLKEQETQVARPAADAYAVVPDASALPVVMAALQRLRAQGVSVQMHSPTAAGEGMGSMKSQFKKADASGARYALVFGADELARGAVTVKPLRDSGEQAERPLAALAEWAATLQSSR
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_XANAC
Sequence: MALERTLSIIKPDAVAKNVIGEIYSRFEKAGLKVVAAKYKQLSRREAEGFYAVHRERPFFNALVEFMISGPVMIQALEGENAVAAHRDLLGATNPKDAAPGTIRADFADSIDANAAHGSDSVENAANEVAYFFAATEVVSR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPIA_BLOFL
Sequence: MISKDKLKKLVGWEALKYIKSNTIIGVGTGSTVNYFIEALSSIKQQIEGVVSSSQHSSNQLKKLGIPLYNLNNLNDLEIYIDSADEIDLHMQMIKGGGGALTKEKIIAFAAKKFICIVDDSKQVNILGRKGPIPVEVIPMARSVVSKSLICLGGLPEYRNGVITDNGNSILDVYNMNITDASLLEQRINNIPGVVSVGLFAQRKADIALIGTQKGIKILNSN
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: SYDND_RICAH
Sequence: MHKYRTHNCSELQISDVGQEVKLSGWVHRRRDHGNLVFIDLRDHYGIIQIVFTDQNPQLMEDASRLRYESVVTVRGTVVARSEDTINNTLPTGHVEVLAVEFIVESAADTLPFVINTEKDAPEDSRLKHRFLDLRREKLHNNIILRSQIISHIRHLMMARGFTEFQTPILTASSPEGARDFLVPSRMHPGKFYALPQAPQQFKQLLMVSGFDRYFQIAPCFRDEDARADRSPGEFYQLDLEMSFVTQEDVFSTIEPVMYDLFNKFTDKKVSATPFVRIPYNESMLKYGSDKPDLRNTIIISDVTEIFRDSDFTIFRENIRKGSIVRAIPAPKAATMPRSFFDKMIEFAISEGAGGLGYIQFSETGETKGAVAKFLSTQQLDSLKATASISNGDAVFFVSDKKEKAARLAGKVRIRLGEELDLLEKDCFKFCWITDFPFYELNEETGKIDFSHNPFSMPQGGLEALENAKTTEALLELNAYQYDIVCNGIELSSGAIRNHKPDIMYKAFSIAGYSEEEVNKRFGGMIRAFKFGAPPHGGIAPGIDRIVMLLAEATNIREVIAFPLNQQAEDLLMNAPSYVEDKALKELSIMLSPSARKNAKKE
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_YERPB
Sequence: MAKHLFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGMVLVGGEVTTNAWVDIEEITRRTIREIGYVHSDMGFDANSCAVLSAIGKQSPDINQGVDRENPLEQGAGDQGLMFGYATNETSVLMPAPITYAHRLVERQAEVRKNGALPWLRPDAKSQVTFQYDDGKIVGIDAVVLSTQHSEDINQKDLHEAVMEEIIKPVLPAEWITAHTKYFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVSYAIGVAEPTSIMVEAFGTEKIPADQLTLLVREFFDLRPYGLIKMLDLLHPIYRETAAYGHFGREHFPWEKTDKAALLRDAAGLK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS1_ANASK
Sequence: MPGTSELITVAVPKGRLLQESSALFERALGVSPRKLLEGTRKLAADAPEAGLRFISIRAGDVASYVEHGAAEVGIVGLDVLREEPRDLYEPLDLGIGRCTVIVARPKGARPLPRGVAPRVATKYLSLAARHFAAKGVPAEIIPLHGSIEVAPSLGLADTIVDITETGETLRANGLVIEEKVLEVSARLVVNRVALKLHPERLRRLIEALRAAVAAAGAEAR
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DER_CLOBK
Sequence: MGKPIVAIVGRPNVGKSTLFNKLAGKRIAIVQDTPGVTRDRIYAEAEWLNYKFTMIDTGGIEPESEDIIVSQMRRQAQIAIEMANVIIFLVDGKEGLAPADEEVAQMLRKSKKPVVLVVNKIDKLKDENNAYEFYNLGIGDPVTISSSQALGLGDMLDRVVEYFKDDELDGEEDERINIAFIGKPNVGKSSLINKLLGEERLIVSDIPGTTRDSIDSYVDTEFGEFTLIDTAGLRRKSKVKEEIERYSVIRTYASIERADVCILMIDATEGISEQDQKIIGYAHDINKAILVIVNKWDLVEKDDKTMDKFKKELKVNLSFMPYAKYLFISAKTGQRVVKVLQTAKECYDNYTKRVKTGVLNDVISQAIMMKEPPIVGTKRLKIYYVTQIGTKPPTFIFFVNDPACIHFSYQRYLENQLRENFDFQGTGIKLEFRERKEK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.