PharMolix/UniProtQA huggingface dataset:
Protein: TM201_MOUSE
Sequence: MEGVSALLASCPTAGLAGGLGVTACAAAGVVLYRIARRVKPTHTMVNCWFCNHDTLVPYGNRNCWDCPHCEQYNGFQENGDYNKPIPAQYMEHLNHVVSSVPSPRDPAQPQQWVSSQVLLCRRCSHHQTTKIKQLAAFTPREEGRYDEEIEVYRHHLEQMYKLCRPCQAAVEYYIKHQNRQLRALLLSHQFRRREADQAHGQSFSSSAVKAPFQVILLRALAFLACAFLLFTTLYGPSEPFTPGAALPPALPPGGNSSAASDNTTSQAEGWQQLLGLLPEHATEKLHEAWAFGQSHQTSIVAVGLLTCLLAMLLAGRIRLRRIDAFSTCLWALLLGLHLAEHYLQAASPGWLDTLKFSTTSLCCLVGFTAAVATRKSTGPRRFRPRRYFSGDSASLFPSSPSLAVPYPSVTSSPASLFIPTPPGFLPLTKQQLFRSPRRVSPSSLPGRLSRALSLGTIPPLTRTDSGYLFSGSRPPSRVSPAGEVSLSDYFSLLSSSFPASPLPSPAPSVASSVASSSGSLRHRRPLISPARLNLKGQKLLLFSSPGEAPNTPSSSEEFSPPNGSLFIESPQLPQRNHTRDTKHTMEMRSMLARDSARSSHSIKKEDESSQSSTCVVDTTTKGCSEETTPWKARVSPSLVRGLLAVSLAVNALFTSAYLYQSLR
What is the function of this protein?
Proposed to be involved in actin-dependent nuclear movement; via SUN2 associates with transmembrane actin-associated nuclear (TAN) lines which are bound to F-actin cables and couple the nucleus to retrograde actin flow.
What are the official names of this protein?
Transmembrane protein 201, Spindle-associated membrane protein 1.
What is the protein family that this protein belongs to?
Belongs to the TMEM201 family.
What are the subcellular locations of this protein?
[Isoform 2]: Nucleus inner membrane; Multi-pass membrane protein. Note=The C-terminal of isoform 2 is located on the nucleoplasmic side. During interphase, isoform 2 is distributed in the inner nuclear membrane and during mitosis, it is found in the ER but it also localizes to the polar regions of the mitotic spindle (By similarity).
Protein: RS17_THEFY
Sequence: MSEKTTAQERNHRKVREGYVVSDKMDKTVVVAVENRFKHPLYGKIIRRTTKYKAHDEANIAGVGDRVRLMETRPLSATKRWRVVEILEKAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: PCKA_SHELP
Sequence: MADGSKQTHKNPSTAQLVEFALARGEGELTANGALVAKTGERTGRSPNDRFIVKEASSENDIDWGSVNKPFAMDAFNALWDRVATYLADKETFVSELEVGADPEHYQPIEVKTETAWHQLFARNLFIVPEQFNVANKPVWQIMNAPGFECDPARDGTNSDATVIINFADRKVLLAGLKYAGEMKKSMFSVQNFLLPAKGVLPMHCSANVGSEGDTTLFFGLSGTGKTTLSADPKRFLIGDDEHGWAPGGVFNIEGGCYAKCIDLSQKNEPVIWDAIRFGTVLENVTLDEQRIPDYSNTELTENSRAAYPLEHIAQRKEENRGAEPNAVVFLTCDVSGVLPPVSKLSKEQAAYHFLSGYTAKVGSTEMGSTSAIQSTFSTCFGAPFFPRPAGVYAELLMKRIESFGSQVYLVNTGWTGGPHGVGKRFDIPTTRAIVDAIVSGELKDVETVHIDKLNLDVPVAVTGVDAKLLNPVNTWADKAEYDKYAQQLAEEFAANFTKYDVSDAIKQAGPKA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRSA_STRPI
Sequence: MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFYEQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAGMTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAKEVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGVSDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIGKELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE
What is the function of this protein?
Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.
What are the official names of this protein?
Foldase protein PrsA.
What is the protein family that this protein belongs to?
Belongs to the PrsA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: SUCC_VEREI
Sequence: MKIHEYQGKDILRQFGVPVPRGIPAFTVQEAVEAAQKLGGPVWVVKAQIHAGGRGKGGGVQLAKTIDEVRRLAGSMLGMQLKTHQTGPEGQKVRRLYIEEGADIGKEYYLSIVTDRATQKLAFIASSEGGMDIEEVKRAKPEMIITEFVDPLAGLGPEQALKIAVGIGLPAPAQAQAQAVDIMRRLYQCYMDTDASLLEINPLNCDGQNRLTALDAKFNFDANALWRHPEIVAYRDFEEEDPAEVLASKFDLAYISMDGNIGCLVNGAGLAMATMDTIKLFGGAPANFLDVGGGATAEKVTEAFKIMLGNPKVKGILVNIFGGIMRCDTIATGVISACKAVNLSVPLVVRMKGTNEEPGKKLLAESGLPIIAADTMADAAQRIVAAVR
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: AROB_PHOPR
Sequence: MERINVNLGDRSYPISIGAELFNTPALFASAISAGRRVVVVSNETVAPLYAAQVMATIRALECEVSLLELPDGEQYKTLETFNQIMTFLLQGNYGRDVVMVALGGGVIGDVVGFAAASYQRGVDFVQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPKAVVIDNQCLKTLPAREFASGMAEVIKYGIIADYEFFVWLEQNIEKLQALDNEALCYAIGRCCQIKADVVASDEKESGVRALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGTVFAAKTAHEQGLLSEEDVIRITRLHERAQLPISKPTSMDYDSFIKHMMRDKKVLSGQLRLVLPTSIGTAEVVSDVPHDVLRRVINA
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_METCA
Sequence: MTTQRLVSAAGQWDEEAIDRAIRPKRLEDYVGQRAMREQMAIFIQAALGRGEALDHVLIFGPPGLGKTTLANIIANELGVNVRHTSGPVLEKAGDLAALLTNLEPRDVLFIDEIHRLGAVVEEVLYPAMEDYQIDIMIGEGPAARSIKLDLPPFTLVGATTRAGLLTSPLRDRFGIVHRLEFYSVEELSRIVARSARILGSEITPEGAAEVARRSRGTPRIANRLLRRVRDFAQVMADGRITGEVAGKALEMLDVDPNGFDQSDRRLLLTMMEKFEGGPVGLDNLAAAIGEERGTIEDVLEPYLIQQGFIMRTPRGRVATRNAYLHFGLKPPQRTNVNEELFGDE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: RLMD_ECOK1
Sequence: MAQFYSAKRRTTTRQIITVSVNDLDSFGQGVARHNGKTLFIPGLLPQENAEVTVTEDKKQYARAKVVRRLSDSPERETPRCPHFGVCGGCQQQHASVDLQQRSKSAALARLMKHEVSEVIADVPWGYRRRARLSLNYLPKTQQLQMGFRKAGSSDIVDVKQCPILVPQLEALLPKVRACLGSLQAMRHLGHVELVQATSGTLMILRHTAPLSSADREKLECFSHSEGLDLYLAPDSEILETVSGEMPWYDSNGLRLTFSPRDFIQVNAGVNQKMVARALEWLDVEPEDCVLDLFCGMGNFTLPLATQAASVVGVEGVPALVEKGQQNARLNGLQNVTFYHENLEEDVTKQPWAKNGFDKVLLDPARAGAAGVMQQIIKLEPIRIVYVSCNPATLARDSEALLKAGYTIARLAMLDMFPHTGHLESMVLFSRVK
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: BETB_BURP1
Sequence: MSVYGLQRLYIAGAHADATSGKTFDTFDPATGELLARVQQASADDVDRAVASAREGQREWAAMTAMQRSRILRRAVELLRERNDALAELEMRDTGKPIAETRAVDIVTGADVIEYYAGLATAIEGLQVPLRPESFVYTRREPLGVCAGIGAWNYPIQIACWKSAPALAAGNAMIFKPSEVTPLSALKLAEIYTEAGVPAGVFNVVQGDGSVGALLSAHPGIAKVSFTGGVETGKKVMSLAGASSLKEVTMELGGKSPLIVFDDADLDRAADIAVTANFFSAGQVCTNGTRVFVQQAVKDAFVERVLARVARIRVGKPSDSDTNFGPLASAAQLDKVLGYIDSGKAEGAKLLAGGARLVNDHFASGQYVAPTVFGDCRDDMRIVREEIFGPVMSILSFETEDEAIARANATDYGLAAGVVTENLSRAHRAIHRLEAGICWINTWGESPAEMPVGGYKQSGVGRENGITTLEHYTRIKSVQVELGRYQPVF
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
What are the official names of this protein?
Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: UVRC_CHLFF
Sequence: MHVKDFSPKIIPPSPGVYLMKDSSGEVLYIGKAKNLRNRITTYFQKQGDSRERIPFLMKKTTDIETILVSNETEALLLENNLIKKYHPKYNVLLKDDKTFFCLAISLSHPWPRIDAIRTKAVTSSKKQIVFGPYVSAEACQTLLEVIGQWFPLRTCSNREFSTRKRPCILYEMKRCLAPCVNFCSQEEYAETLEKAVLFLKGQVSEIIQKLEKSIEKASQEQKFEQAGMYYRTLKLIQQAMVKQHVEKFHFQNIDAIGLYRKHQETVITVLTIRSGKLLGARHFPFSENAQEDSDLLSSFILQYYANQPHIPKEILTPFSLNIPDLPHLLNKEAPPRIRSPKTGYGKELLNLAKNNAEMHAQTSVQSSVLPYEEMKKILKTQDYPYRIECYDNAHLQGSHAVGVYIVYENNALSPKNYRTFAISSSAHNDLAAFHEVLSRRFSSTSSPLPDMIVIDGGRLQYSQAKKTLKKLNLTGIQIVSIAKEASNHSGSLRHEKLFCDIFPQGIQLPPTSKLLQFFQKLRDEAHRFAISKHRKKRSRDLLLPQEKIAGIGEVKRKRLLKKFKSWKQVMQASQGELETIPGLTKKDIKQLLAKQAEVINLEK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRVP_VIPBE
Sequence: MIAFLVLPILAAVLQQSSGNVDFDSESPRKPEIQNEIIDLHNSLRRSVNPTASNMLKMEWYPEAAANAERWAFRCILSHSPRDSRVIGGIKCGENIYMSTSPMKWTAIIHEWHGEEKDFVYGQGASPANAVVGHYTQIVWYKSYRSGCAAAYCPSSEYKYFYVCQYCPAGNMQGKTATPYTSGPPCGDCPSACDNGLCTNPCTHEDKFTNCKDLVKQGCNNNYLKTNCPASCSCHNEII
What is the function of this protein?
Blocks contraction of smooth muscle elicited by high potassium-induced depolarization, but does not block caffeine-stimulated contraction.  May target voltage-gated calcium channels in smooth muscle (By similarity).
What are the official names of this protein?
Cysteine-rich venom protein, CRVP.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Secreted.
Protein: NUD22_MOUSE
Sequence: MDPEVSLLLLCPLGGLSQEQVAVELSPAHDRRPLPGGDKAITAIWETRQQAQPWIFDAPKFRLHSATLVSSSPEPQLLLHLGLTSYRDFLGTNWSSSASWLRQQGAADWGDKQAYLADPLGVGAALVTADDFLVFLRRSQQVAEAPGLVDVPGGHPEPQALCSGGIPRHKDLPGLLVVRELFSSVLQEICDEVNLPLHTLSQPLLLGIACNETSAGRASAEFYVQCSLTSEEVRSYYLSGGPEAHESTGIIFVETQRVQRLQETEMWAQLCPSAKGAILLYNRHPPLQSGVGKSHLSHPSAPALSLQL
What is the function of this protein?
Hydrolyzes UDP-glucose to glucose 1-phosphate and UMP and UDP-galactose to galactose 1-phosphate and UMP.  Preferred substrate is UDP-glucose.
What are the official names of this protein?
Uridine diphosphate glucose pyrophosphatase NUDT22, UDPG pyrophosphatase, UGPPase, Nucleoside diphosphate-linked moiety X motif 22, Nudix motif 22.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
Protein: DNAK_PSEFS
Sequence: MGKIIGIDLGTTNSCVSVMENGKAKVIENAEGARTTPSIIAYANDGEILVGQSAKRQAVTNPHNTLYAVKRLIGRKFDEEVVQKDIKMVPYKIAKADNGDAWVEVNGNKMSAPQISAEVLKKMKKTAEDYLGETVTEAVITVPAYFNDSQRQATKDAGRIAGLDVKRIINEPTAAALAYGMDKAKGDHTVIVYDLGGGTFDVSVIEIAEVDGEHQFEVLATNGDTFLGGEDFDIRLIDYLVDEFKKESGMNLKGDPLAMQRLKEAAEKAKIELSSSMSTDVNLPYITADATGPKHLNVKISRAKLEALVEDLVQRTIEPCRIALKDAGIDVGSINDVILVGGQTRMPLVQQKVTEFFGKEARKDVNPDEAVAMGAAIQGAVLAGDVKDVLLLDVSPLTLGIETMGGVMTALIEKNTTIPTKKSQVFSTADDNQGAVTIHVLQGERKQAAQNKSLGKFDLAEIPPAPRGVPQIEVTFDIDANGILHVGAKDKATGKEQKITIKANSGLSDEEIQQMIRDAEANADADAKFAELAGARNQGDALVHSTRKMVADAGDKVTAEEKAAIEAAVVALEAAVKGDDKAAIEAKIEELSKVSAPVAQKMYAEQGQPADGAAQQAEPEAKHDDVVDAEFEEVKDQK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: TRAM4_ECOLX
Sequence: MSDQIEELIREIAAKHGIAVGRDDPVLILHTINARLMADSAAKQEEILAAFKEELEGIAHRWGEDAKAKAERMLNAALAASKDAMAKVMKDSAAQAAEAIRREIDDGLGRQLAAKVADARRVAMMNMIAGGMVLFAAALVVWASL
What are the official names of this protein?
Protein TraM.
What is the protein family that this protein belongs to?
To plasmid R751 TraM.
Protein: OBG_ECO55
Sequence: MKFVDEASILVVAGDGGNGCVSFRREKYIPKGGPDGGDGGDGGDVWMEADENLNTLIDYRFEKSFRAERGQNGASRDCTGKRGKDVTIKVPVGTRVIDQGTGETMGDMTKHGQRLLVAKGGWHGLGNTRFKSSVNRTPRQKTNGTPGDKRELLLELMLLADVGMLGMPNAGKSTFIRAVSAAKPKVADYPFTTLVPSLGVVRMDNEKSFVVADIPGLIEGAAEGAGLGIRFLKHLERCRVLLHLIDIDPIDGTDPVENARIIISELEKYSQDLAAKPRWLVFNKIDLLDKAEAEEKAKAIAEALGWEDKYYLISAASGLGVKDLCWDVMTFIIENPVVQAEEAKQPEKVEFMWDDYHRQQLEEIAEEDDEDWDDDWDEDDEEGVEFIYKR
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_METBU
Sequence: MPGNTFGHSFRITTWGESHGRALGVVIDGVPAGLPLDTEIVQKELDRRRPGQSAVSTPRSETDKVEIISGIFEGKTTGTPISMMVWNKDADSSSYDNIKDLPRPGHADYPYMEKYGIRDHRGGGRSSARETIGRVAAGAVAKEILSIFGIDIIAHVTELGGIRAKEMPFDTIKEHLEKTPVRCADLEAAQLMLEKVGKAREEHESIGGVVEIIAIGLPPGIGEPVFDKLDADIAKAIMSIGAVKGVEIGIGNEAAQMKGSQMNDPFILEDGKIIAQTNNAGGILGGLSTGMPIICRASVKPTPSISKVQHTVNTKEMKNSDIIIKGRHDPTIPPRMVPVAEAMMALVLVDHMIRSGHIHPNSLLKQ
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: PP14B_MOUSE
Sequence: MADSGPAGGAALAAPAPGPGSGSTGPRVYFQSPPGAAGEGPGGADDDGPVRRQGKVTVKYDRKELRKRLNLEEWILEQLTRLYDCQEEEIPELEIDVDELLDMESDDTRAARVKELLVDCYKPTEAFISGLLDKIRGMQKLSTPQKK
What is the function of this protein?
Inhibitor of PPP1CA.  Has over 50-fold higher inhibitory activity when phosphorylated.
What are the official names of this protein?
Protein phosphatase 1 regulatory subunit 14B, Phosphatase holoenzyme inhibitor 1, PHI-1, Phospholipase C-beta-3 neighbouring gene protein.
What is the protein family that this protein belongs to?
Belongs to the PP1 inhibitor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SODM_DICDI
Sequence: MLPRSLKLIKKVGESNGLRNFGSQSNSYTLPDLPYDYGALSPVISPEIMTLHHKKHHQTYVNNLNIALDKLSSASSAKDVAQMIALQSAIKFNGGGHVNHSIFWTNLAPKNQDGGVAPSGPLADAINKQYGSIEKLIEKMSAETTAIQGSGWGWLGYDKANDRLVIQTQQNQDPLSVSGYVPLLGIDVWEHAYYLDYKNVRADYVKNIWQIVNWKNVAERYNTAKK
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn], mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: AQP5_LACBI
Sequence: MAEFVGVALLVIFGAGAACQVILSTNPGVSPSERGSFLSINFGWAIGIATGAWVSTGMSEGHINPAITIGMATYRGFPWREVPGYIFGQVLGGFVGAALVYANYFHAIDIFEGGHRTQATASLFATFALPYMTQASCFFSEFLATAVLFIVFLALNDKHNGALTNGLLPFALFILFIGLGASLGMQTGYAVNPARDFGPRLFLAMAGYGKAVFNYRRQYWIWAPIIAPILGAQAGGLLYDTFIYNGDDSPIKWR
What is the function of this protein?
Water channel required to facilitate the transport of water across membranes (PubMed:25323307).  Does not mediate the transport carbon dioxide across the membrane (PubMed:25857333).
What are the official names of this protein?
Aquaporin-5.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
Protein: Y5073_BACC3
Sequence: MIKPLIEFCVGNLASGSQAALEKLEKDPNLDVMEYGCLGYCGICFEGPFALVNGEVVQGSTVEELVNNVYEYLDENPMF
What are the official names of this protein?
UPF0349 protein BCA_5073.
What is the protein family that this protein belongs to?
Belongs to the UPF0349 family.
Protein: RL30_COXBU
Sequence: MVQEKKLRVTLVKSKYGRKPGHRECIEGLGLRRMHQTVEVTDTPANRGMIEKVSYLLMIDEEV
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: HLDD_DECAR
Sequence: MYIVVTGAAGFIGSNIVKALNERGITNIIAVDNLTKADKFKNLIDCDIVDYLDKNDFIERIQAGHFDGEIDAILHEGACSDTMETDGRYMMENNYRYSMILLDWCLDQDVQFLYASSAATYGSSGTFKEERQYEGPLNVYGYSKFLFDQIVRQRLAQNPSSQIVGFRYFNVYGPRETHKGRMASVAFHNFNQFRADGKVKLFEGSHGYPDGDQQRDFVFVGDVAKVNLFFLDHPEKSGIFNLGSGRAQSFNDVAVAAVNGCRKARSESALSLEELRAQGLLEYVAFPEALKGKYQAFTQADLGKLRAAGYDAPMATVEEGVSQYIEWLQRNV
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: SPC25_DROMA
Sequence: MAIIMAESSYERRVKALYEKQIRMEALEAKFIKKVYKFNSNLLDVKEAACRHQRKVGKLQKVLMERREELDKRVSFIEELDRELEATKLRDLAMKDRIKQQKMLARQRKNEIMESIHTLSKTTGTYINQDALPARVKGVTVLRGDKRNQLIPFDLKSTDVEGLDSLCQHLESLNVDMAQWQQLISLAMDVAMESRAPTTPPKEATNCNSIIEIDLTSPTCHI
What is the function of this protein?
Acts as a component of the essential kinetochore-associated Ndc80 complex, which is required for chromosome segregation and spindle checkpoint activity during meiosis and mitosis.  Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.  Participates in SAC signaling that responds specifically to disruptions in spindle microtubule dynamics.  The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules.
What are the official names of this protein?
Kinetochore protein Spc25.
What is the protein family that this protein belongs to?
Belongs to the SPC25 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore.
Protein: ISPD_LISMO
Sequence: MNYELVFLAAGQGKRMNAQKNKMWLELVGEPIFIHALRPFLADNRCSKVIVVCQEEERKHVKELMSQLNVAEHRIEIVKGGSERQYSVAAGLERCGTGRVVLVHDGARPFITLDIIDRLLIGVEQSKAAICAVKVKDTVKRVMNGVVQETVDRENLWQVQTPQAFELPILRKAHQLARKEQFLGTDEASLVERIPCPVAIVQGSYYNIKLTTPEDMPLAKAILGELGGIAND
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: MAP1_STAEQ
Sequence: MIVKTDEELQALKEIGYICAKVRDTMKEATKPGVTTRELDHIAKDLFEEHGAISAPIHDENFPGQTCISVNEEVAHGIPGKRVIHEGDLVNIDVSALKNGYYADTGISFVVGKSDQPLKQKVCDVATMAFENAMKKVKPGTKLSNIGKAVHATARQNDLTVIKNLTGHGVGQSLHEAPNHVMNYFDPKDKTLLKEGQVIAVEPFISTHATFVTEGKNEWAFETKDKSYVAQIEHTVIVTKDGPLLTTKIDD
What is the function of this protein?
Removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).  Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.
What are the official names of this protein?
Methionine aminopeptidase, MAP, MetAP, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
Protein: RIMK_ALCBS
Sequence: MKIAILSRNKRLYSTRRLVEAGEAAGHEMHVIDTLRCYMSMVAHKPEIHYKGEVLEGFDAVIPRIGASITQYGTAVVRQFEMMGVFPVNESVAISRSRDKLRSLQLLSRKGVGLPITGFAHSPDDIPDLINMVRGAPLVIKMLEGTQGIGVVLAETRKAAESVIEAFMGLNVSVMVQEYIKEAGGADIRCFVVGGKVIAAMKRQAAPGEFRSNLHRGGSASLIRITPEERATAVRAARIMGLNVAGVDILRSHHGPVVMEVNSSPGLEGIETATNKDVAGLLIKFIEKDARPYRTQTKGSKG
What are the official names of this protein?
Probable alpha-L-glutamate ligase.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: KDSB_SHIBS
Sequence: MSFVVIIPARYASTRLPGKPLVDINGKPMIVHVLERARESGAERIIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLAEVVEKCAFSDDTVIVNVQGDEPMIPATIIRQVADNLAQRQVGMATLAVPIHNAEEAFNPNAVKVVLDAEGYALYFSRATIPWDRDRFAEGLETVGDNFLRHLGIYGYRAGFIRRYVNWQASPLEHIEMLEQLRVLWYGEKIHVAVAQEVPGTGVDTPEDLERVRAEMR
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS_MAGSA
Sequence: MTVETPPIPDDATPMMAQYLAIKRAHPDCLLFYRMGDFYELFFDDAVKASAALDIALTKRGKHAGEDIAMCGVPVRAYEAYLAKLVRSGFKVAIGEQMEDPAEAKKRGSKSVVARDVVRVITAGTLTEDTLLDARSHNYLAAVAEAQGTLGLAWVDVSTGDFAMQAIAPKTLAAALARLSPGELLVSDRLLGAADFFDVWADWKNVLSPLPTARFDSENSRRRLEALYGVGALDGFGAFSRAELAAGGALVDYVELTQKGKLPRLSLPKRLAEGAVMEIDAATRRNLELAETLSGERRGSLLATIDRTVTGAGARLLAAQLAAPLTDPHAIEWRLDMVGFFVEHESVRAQLRETLKRCPDVERALSRLSLGRGGPRDLANVRDALAEIPALRMLVTQSHLDTPPGINQCARELGEHSALVDRLQRALAPDLPLNARDGGFIAQGYHEGLDELKGLKTESNGLMMRLEKRYQDETGIASLKIRHNNIIGHHIEVPSKQADRLGEGYIHRQTMANAARYTTTELIELAGKITGAADRALALEMELLADLIGEVTARAAEIALAAAALAGLDCASALGEMASSARWSRPRVDDSTAFDIRGARHPVVEAALEAARSGPFVANDCDLADSQRLWLVTGPNMAGKSTFLRQNAVIAILAQMGSFVPAESVHMGVVDRLFSRVGAADDLARGRSTFMVEMVETAAILNQAGPRALVILDEIGRGTATFDGLSIAWAVVEHLHEVNRCRALFATHYHELTRLTSRLAALSCHMMRVKEWQGDVVFLHEVGAGAADRSYGIHVARLAGLPPAVVGRAEEVLGILEKSDQASGMARLADDLPLFAALAKPRPAATALPQASPLEEALKAVNPDDLTARQALDLVYELKRLL
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.