PharMolix/UniProtQA huggingface dataset:
Protein: CYSD_SHEB9
Sequence: MAGRELSHLQQLEAESIQIIREVAAEFDNPVMLYSIGKDSSVMLHLARKAFYPGKIPFPLLHVDTGWKFKEMIAFRDAQAKKFGFELLTHINPEGLAQGINPFDHGSAKHTDIMKTQGLKQALNQYGFDAAFGGARRDEEKSRAKERVYSFRDRHHRWDPKNQRPELWRTYNGAVNKGESIRVFPLSNWTELDIWQYIYQENIELVPLYFAAKRQVVERGGQLIMADDERMKLAEGEQIKEEVVRFRTLGCYPLTAAMHSEADSLEKIIEEMLLTRSSERQGRLIDSDQSASMEQKKRQGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: PVK3_ARCTE
Sequence: GSSGMIPFPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-3, ArcTe-PVK-3.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: KCD11_BOVIN
Sequence: MLGAMFRAGTPMTPNLNPEGGGHYFIDRDGKAFRHILNFLRLGRLDLPLGYGETALLRAEADFYQIRPLLDALRELEASRGTPAPTAALLHADVDSSPRLVHFSARRGPHHYELSSVQVDTFRANLFCTDPECLGALRARFGVTNEDRAEGGPHFRLEWAPRPAELPEVEYRRLGLQPLWTGAPGEPRDVVGTPSFLEEVLRVALEHGFRLDSVFPDPEDLLNSRSLRFVRH
What is the function of this protein?
Plays a role as a marker and a regulator of neuronal differentiation; Up-regulated by a variety of neurogenic signals, such as retinoic acid, epidermal growth factor/EGF and NGFB/nerve growth factor.  Induces apoptosis, growth arrest and the expression of cyclin-dependent kinase inhibitor CDKN1B.  Plays a role as a tumor repressor and inhibits cell growth and tumorigenicity of medulloblastoma (MDB).  Acts as probable substrate-specific adapter for a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex towards HDAC1.  Functions as antagonist of the Hedgehog pathway on cell proliferation and differentiation by affecting the nuclear transfer of transcription factor GLI1, thus maintaining cerebellar granule cells in undifferentiated state, this effect probably occurs via HDAC1 down-regulation, keeping GLI1 acetylated and inactive (By similarity).
What are the official names of this protein?
BTB/POZ domain-containing protein KCTD11, KCASH1 protein, Potassium channel tetramerization domain-containing protein 11, RING-type E3 ubiquitin transferase subunit KCTD11.
Protein: RPN1_NEUCR
Sequence: MAQESDLSKTADKGKGKAVDDEKKHQDVDGKTPANGKKEEEQNASEELSEEDQQLKSELEMLVERLTESDATLYKPALEAMKNSIKTSTSSMTAVPKPLKFLRPHYETMTKLYDEWPAGDDKSSLADVLSVIGMTYSDEDRQDTLKYRLLSPTQDIGSWGHEYVRHLALEIGEVYAKRIANDEPTQELVDLALVLVPLFLKSNAEADAVDLMSELEIIEELPKFLDENTYSRVCLYMVSMVNLLTYPDNETFLRVAHSIYKKYNQHTQAMVLAIRLNDLGLIEKDFEAADEDPALRKQLAFLIARQGIPLEFERSNDDDEKIYECLSNQKLSEYFKSLGKELNILEPKTTEDIYKSHLESSRVAGMTNFDSARHNLAAGFVNAFVNAGFGSDKMMLVGKDKDSWVWKTKDEGMMSTVASLGTLLLWDVENGLDHVDKYTYLEEEQIQAGAYLAIGIMNTNVRTDSEPAMALLADPDKLAHKNPLIRVATIMGLGLAYAGSCKEELLSFLVNIISDPEESMQVSAMAALACGMIFVGSSNSEVSEAIVTTLLDEESGSRLNDKWSRFLALGLGLLYFGRQEQVDVILETLKAVEHPMAKPTAVLAEICAWAGTGAVLKIQELLHICNEHIEDGEEKKGEELLQAYAVLGIGLIAMGEDVGQEMVLRHFGHLMHYGEANIRRAVPLAMGLISPSNPQMKVYDTLSRYSHDNDNEVAINAIFAMGLLGAGTNNARLAQLLRQLASYYHRDQESLFMVRIAQGLLHMGKGTLSVSPFHTDRQVLSNVATAGLLAVLVAMIDAKQFITSKSHYLLYWIVTAMHPRMLVTLDEDLKPLTVNVRVGQAVDVVGQAGRPKTITGWQTQSTPVLLGYGERAELEDDQYISLSSTLEGLVILRKNPDWEGEK
What is the function of this protein?
Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
What are the official names of this protein?
26S proteasome regulatory subunit rpn-1.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S2 family.
Protein: Y2317_BREBN
Sequence: MMSGEVMLVILIVIGLIGRSPIIATAASILLVLKLTALERFFPTVERRGLELGLLFLTISVLVPFASEKISWKDVTPLFTTVVGLTALAGGAIATWMNGKGLDLLRSEPHMIVGLVIGSIIGIVFFRGIPVGPLMAAGITAFVLKLWEWFGSR
What are the official names of this protein?
UPF0756 membrane protein BBR47_23170.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YKTA_BACSU
Sequence: MEYQYPMNEDWTTEEAVDVIAFFQQVELAYEKGADREELLKAYRRFKEIVPGKAEEKKLCGEFEEQSTYSPYRTVKQARESDHAKIKM
What are the official names of this protein?
UPF0223 protein YktA.
What is the protein family that this protein belongs to?
Belongs to the UPF0223 family.
Protein: FLIC2_PROMI
Sequence: MAQVINTNYLSLVTQNNLNRSQSALGNAIERLSSGMRINSAKDDAAGQAIANRFTSNINGLTQASRNANDGISVSQTTEGALNEINNNLQRIRELTVQAKNGTNSNSDINSIQNEVNQRLDEINRVSEQTQFNGVKVLSGEKSKMTIQVGTNDNEVIEFNLDKIDNDTLGVASDKLFDAKTEKKGVTAAGDAIDANALGISGSKKYVTGISVKEYKVDGKVSSDKVVLNDGSDDYIVSKSDFTLKSGTTTGEVEFTGSKTTKFTADAGKDVKVLNVKDDALATLDNAISKVDESRSKLGAIQNRFQSTINNLNNTVNNLSASRSRILDADYATEVSNMSKNQILQQAGTAVLAQANQVPQTVLSLLR
What is the function of this protein?
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
What are the official names of this protein?
Flagellin 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial flagellin family.
What are the subcellular locations of this protein?
Secreted. Bacterial flagellum.
Protein: PRMA_THEP3
Sequence: MKWIEVQVTTTQEAEEAVTNIMHELGAGGVVIKNPNDVKLLAQSDNWDYLDSSLFEEEGNIKVFAYFPIASDTTDKINILKDRIVELKSFGIDIGNFDVKVSEVDEADWENNWKQYYKPLKIGKKIVIKPSWEEYVSQGEEIIIELDPGMAFGTGTHETTKMCLEFLEDIVMPESIVFDVGCGSGILSITSSKLGAKEVYAADIDEVSVEVARQNVELNNLQNVKVFKSDLLSEFRGKADIIVANIIADVIIKLSAEVPKYLKEEGLFLASGIIKSRKEEVLQKVEEFFEVLQIREEGEWCAILSRKK
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: X_HBVE1
Sequence: MAARLCCQLDPARDVLCLRPVSAESCGRPVSGSLGDLSSPSPSAVPADHGAHLSLRGLPVCAFSSAGPCALRFTSARRMETTVNAHQILPKVLHKRTLGLSAMSTTDLEAYFKDCLFKDWEELGEEIRLKVFVLGGCRHKLVCAPAPCNFFTSA
What is the function of this protein?
Multifunctional protein that plays a role in silencing host antiviral defenses and promoting viral transcription.  Does not seem to be essential for HBV infection.  May be directly involved in development of cirrhosis and liver cancer (hepatocellular carcinoma).  Most of cytosolic activities involve modulation of cytosolic calcium.  The effect on apoptosis is controversial depending on the cell types in which the studies have been conducted.  May induce apoptosis by localizing in mitochondria and causing loss of mitochondrial membrane potential.  May also modulate apoptosis by binding host CFLAR, a key regulator of the death-inducing signaling complex (DISC).  Promotes viral transcription by using the host E3 ubiquitin ligase DDB1 to target the SMC5-SMC6 complex to proteasomal degradation.  This host complex would otherwise bind to viral episomal DNA, and prevents its transcription.  Moderately stimulates transcription of many different viral and cellular transcription elements.  Promoters and enhancers stimulated by HBx contain DNA binding sites for NF-kappa-B, AP-1, AP-2, c-EBP, ATF/CREB, or the calcium-activated factor NF-AT.
What are the official names of this protein?
Protein X, HBx, Peptide X, pX.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus protein X family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Host mitochondrion. Note=Mainly cytoplasmic as only a fraction is detected in the nucleus. In cytoplasm, a minor fraction associates with mitochondria or proteasomes.
Protein: TOLB_HAES1
Sequence: MKFSAYLTTLFIVLFSLFIQTVQAESEVRIVIDEGVDSARPIAIIPFKWNGSDSMPIDVADIISADLRNSGKFNPIAVSKMPQKPTSASEVISDVWSSLGIDAVVVGQVTPNEKGYSIAYQLVDTIGASGNAGEVLSQNQYAVPKNAIRLGAHTISDEVFEKLTAIRGAFRTKIAYVVQKHGGSKPYQVRVADYDGHNQFIVYSSSQPLMSPAWSPDGSKLAYVSFENRKSQLIVHDLQSGARRVIAAFPGHNGAPAFSPDGSKIAFASSKDGVLNIYVMNLGNGTISQLTSGAGNNTEPSWSPDGQSIIFTSDRAGGPQIYQMDVFGNGISLVSAGRGYSGKISADGSILVMIYGDNIVKKDLATGVTEMLSSTFLDESPSISPNGIMIIYSSTQGLGKVLQLVSADGRFKARLPSSDGQIKFPAWSPYLNKN
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: HTPX_STRP7
Sequence: MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLVIALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFIIDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAVALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLVQLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKGGGFQKLFYTHPPISERIERLKHM
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CAPP_ECO24
Sequence: MNEQYSALRSNVSMLGKVLGETIKDALGEHILERVETIRKLSKSSRAGNDANRQELLTTLQNLSNDELLPVARAFSQFLNLANTAEQYHSISPKGEAASNPEVIARTLRKLKNQPELSEDTIKKAVESLSLELVLTAHPTEITRRTLIHKMVEVNACLKQLDNKDIADYEHNQLMRRLRQLIAQSWHTDEIRKLRPSPVDEAKWGFAVVENSLWQGVPNYLRELNEQLEENLGYKLPVEFVPVRFTSWMGGDRDGNPNVTADITRHVLLLSRWKATDLFLKDIQVLVSELSMVEATPELLALVGEEGAAEPYRYLMKNLRSRLMATQAWLEARLKGEELPKPEGLLTQNEELWEPLYACYQSLQACGMGIIANGDLLDTLRRVKCFGVPLVRIDIRQESTRHTEALGELTRYLGIGDYESWSEADKQAFLIRELNSKRPLLPRNWQPSAETREVLDTCQVIAEAPQGSIAAYVISMAKTPSDVLAVHLLLKEAGIGFAMPVAPLFETLDDLNNANDVMTQLLNIDWYRGLIQGKQMVMIGYSDSAKDAGVMAASWAQYQAQDALIKTCEKAGIELTLFHGRGGSIGRGGAPAHAALLSQPPGSLKGGLRVTEQGEMIRFKYGLPEITVSSLSLYTGAILEANLLPPPEPKESWRRIMDELSVISCDLYRGYVRENKDFVPYFRSATPEQELGKLPLGSRPAKRRPTGGVESLRAIPWIFAWTQNRLMLPAWLGAGTALQKVVEDGKQSELEAMCRDWPFFSTRLGMLEMVFAKADLWLAEYYDQRLVDKALWPLGKELRNLQEEDIKVVLAIANDSHLMADLPWIAESIQLRNIYTDPLNVLQAELLHRSRQAEKEGQEPDPRVEQALMVTIAGIAAGMRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: RNY_STAAE
Sequence: MNLLSLLLILLGIILGVVGGYVVARNLLLQKQSQARQTAEDIVNQAHKEADNIKKEKLLEAKEENQILREQTEAELRERRSELQRQETRLLQKEENLERKSDLLDKKDEILEQKESKIEEKQQQVDAKESSVQTLIMKHEQELERISGLTQEEAINEQLQRVEEELSQDIAVLVKEKEKEAKEKVDKTAKELLATAVQRLAADHTSESTVSVVNLPNDEMKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARTALVNLVSDGRIHPGRIEDMVEKARKEVDDIIREAGEQATFEVNAHNMHPDLVKIVGRLNYRTSYGQNVLKHSIEVAHLASMLAAELGEDETLAKRAGLLHDVGKAIDHEVEGSHVEIGVELAKKYGENETVINAIHSHHGDVEPTSIISILVAAADALSAARPGARKETLENYIRRLERLETLSESYDGVEKAFAIQAGREIRVIVSPEEIDDLKSYRLARDIKNQIEDELQYPGHIKVTVVRETRAVEYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y, Conserved virulence factor A.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: GCSH_ECO27
Sequence: MSNVPAELKYSKEHEWLRKEAYGTYTVGITEHAQELLGDMVFVDLPEVGATVSAGDDCAVAESVKAASDIYAPVSGEIVAVNDALSDSPELVNSEPYAGGWIFKIKASDESELESLLDATAYEALLEDE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: CRGM1_CHIID
Sequence: MGKIIFYEDRNFQGRSYECMSDCSDITTYMSRCQSCRVESGCFMVYERPNFMGMQFFLRRGEYHDMQRMMSMGMMFDSIRSCRYPYRAFRMRIYEREYFGGQMSELMGDCDSIMDRFRMSDCMYCHVMDGHWLMYEQAHYRGKMMYLRPGEYRSFRDMGMSGMRFMSMRRITDMC
What is the function of this protein?
Crystallins are the dominant structural components of the vertebrate eye lens.
What are the official names of this protein?
Gamma-crystallin M1, Gamma-M1.
What is the protein family that this protein belongs to?
Belongs to the beta/gamma-crystallin family.
Protein: NU2C_NOSP7
Sequence: MDFANIASQLNAGTILPEGIVILTLLGVLIVDLILGRTSARWIGYLAIAGLFTSIVALYFQWDNPNPISFTGGFNGDDLSIVFRGIIALSAAVTILMSIRYVDQSGTPLAEFIAILLSATLGGMFLSGASELVMIFISLETLSISSYLLTGYTKRDPRSNEAALKYLLIGASSTAVFLYGVSLLYGLSGGQTELSAIANGIATAKVGQSLGLVIALVFAIAGIGFKISAAPFHQWTPDVYEGAPTPVIAFLSVGSKAAGFALAIRLLTTAFPLVADEWRFVFTALAVLSMILGNVVALAQTSMKRMLAYSSIAQAGFVMIGLIAGTQAGYASMIFYLLVYLFMNLCGFTCIILFSLRTGTDQIAEYSGLYQKDPLLTLGLSIALLSLGGIPPLAGFFGKIYLFWAGWQAGLYWLVLLGLVTTVVSIYYYIRVVKMMVVKEPHEMSDAVKNYPQVRWDLPGLRPLQVGLVITLIATSLAGILSNPLFTLANNSISNTPFLQATINSHVEAQNLLLLPKLDSVSQSQPSVDSTAKI
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2, NAD(P)H dehydrogenase subunit 2, NADH-plastoquinone oxidoreductase subunit 2, NDH-1, subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: SL3_ECHCS
Sequence: WGDSSSSASACWSCSSPLSGTEAGVCCPLGWSGYDQNCYKAFEELMNWADAEKFCTQQHKGSHLVSLHNIAEADFVVKKIVSVLKDGVIWMGLNDVWNECNWGWTDGAQLDYKAWNVESNCFIFKTAENHWSRTDCSGTHSFVCKSPA
What is the function of this protein?
Interferes with one step of hemostasis (modulation of platelet aggregation, or coagulation cascade, for example).
What are the official names of this protein?
Snaclec 3, C-type lectin 3, CTL-3.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: RPOC_PARPJ
Sequence: MKALLDLFKQVQQPEVFDAIKIGLASPDKIRSWSFGEVKKPETINYRTFKPERDGLFCAKIFGPIKDYECLCGKYKRLKHRGVICEKCGVEVTLAKVRRERMGHIELASPVAHIWFLKSLPSRLGMVLDMTLRDIERVLYFEAYVVIDPGMTPLKARQIMTEEDYYNKVEEYGDEFRAEMGAEGVRELLRAINIDEQVEMLRTELKNTGSEAKIKKYAKRLKVLEAFQRSGIKPDWMVLEVLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPEIIVRNEKRMLQEAVDSLLDNGRRGKAMTGANKRPLKSLADMIKGKGGRFRQNLLGKRVDYSGRSVIVVGPTLKLHQCGLPKLMALELFKPFIFNKLEVMGVATTIKAAKKEVENQTPVVWDILEEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQMEARTLMLASNNVLFPANGDPSIVPSQDIVLGLYYATREAVNAKGEGLTFTGVSEALRAYENKEVELASRVNVRITEMVHNEDKSEGAPAFVPKITLYPTTVGRAILSEILPPGLPFSVLNKPLKKKEISRLINTAFRKCGLRETVIFADQLMQSGFRLATRAGISICVDDMLVPPQKETIVGDAAKKVKEYDRQYMSGLVTSQERYNNVVDIWSATSEAVGKAMMEQLSTEPVTDRDGNETRQESFNSIYMMADSGARGSAVQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVTQDLVVVEDDCGTSNGVAMKALVEGGEVVEALRDRILGRVTVADVVNPESQETLYETGTLLDEDAVEEIERLGIDEVRVRTPLTCETRYGLCAACYGRDLGRGSSVNVGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAVASSVEAKSNGTVRFTATMRYVTNAKGEQIVISRSGEAMITDDHGRERERHKVPYGATLLQLDGAQIKAGTQLATWDPMTRPIITEWGGTVKFENVEEGVTVAKQIDDVTGLSTLVVIDVKRRGSQASKTVRPQVKLLDANGEEVKIPNTEHSVQIGFQVGALITVKDGQQVQVGEVLARIPVESQKTRDITGGLPRVAELFEARSPKDAGILAEVTGTTSFGKDTKGKQRLVITDLDGNQHEFLIAKEKQVLVHDGQVVNKGEMIVDGPADPHDILRLQGIEALSRYIVDEVQDVYRLQGVKINDKHIEVIVRQMLRRVQITDNGDTRFIPGEQVERSDMLDENDRMIAEDKRPATYENVLLGITKASLSTDSFISAASFQETTRVLTEAAIMGKRDDLRGLKENVIVGRLIPAGTGLAFHKARKSKELSDRERFDQIAAEESFEFGTPETPAAEQQHSGE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: KGUA_CORDI
Sequence: MSGDNPVGRLVVLAGPSAVGKSTVVHRLREEIEDLYFSVSMTTRAPRPGERDGVDYFFVSPEEFQSKIDAGEMLEWADIHGGLQRSGTPAGPVEAALLAGRPVLVEVDLVGARNVASLKPESETVFLAPPSWEVLVERLTGRGTEPEDVITRRLETAKNELTAQHEFKHVVVNEDVEKAVSDIKEILVGRR
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAX_I96A0
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDFHFIDERGESTIIESGDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHTYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFVSPREAKRQLKKDLKSQGLCAGLPTKVSHLISPALKNLEPMWMDSNRTAALRASFLKCRKK
What is the function of this protein?
May play a role in the modulation of host immune response.
What are the official names of this protein?
Protein PA-X.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA-X family.
Protein: ESTR2_MYCTU
Sequence: MRYLIATAVLVAVVLVGWPAAGAPPSCAGLGGTVQAGQICHVHASGPKYMLDMTFPVDYPDQQALTDYITQNRDGFVNVAQGSPLRDQPYQMDATSEQHSSGQPPQATRSVVLKFFQDLGGAHPSTWYKAFNYNLATSQPITFDTLFVPGTTPLDSIYPIVQRELARQTGFGAAILPSTGLDPAHYQNFAITDDSLIFYFAQGELLPSFVGACQAQVPRSAIPPLAI
What is the function of this protein?
Hydrolyzes ester substrates carbon chain lengths ranging from C2 to C14 (PubMed:25224799).  In vitro, acetate (C2), butyrate (C4) and caprylate (C6) are hydrolyzed with high efficiency.  Has lower activity against laurate (C12), myristate (C14) and caproate (C8), and weak activity against palmitate (C16) (PubMed:25224799).
What are the official names of this protein?
Esterase Rv3036c.
What is the protein family that this protein belongs to?
Belongs to the RsiV family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Secreted, cell wall. Note=Probably anchored in the cell wall and cell membrane via an N-terminal transmembrane helix.
Protein: RL17_SALSV
Sequence: MRHRKSGRQLNRNSSHRQAMFRNMAGSLVRHEIIKTTLPKAKELRRVVEPLITLAKTDSVANRRLAFARTRDNEIVAKLFNELGPRFASRAGGYTRILKCGFRAGDNAPMAYIELVDRSEKTEAAAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: GPR37_MOUSE
Sequence: MPARGAPLSRTSRLLLLLLFKVSVSAALSFVPEPRNGTCLGESCSPLIQRRSRDARGPGNSAKDALRVHVPREKLEAEVRGATSWDLPPPRGGDTGVIEEAAAAGPLGPPTKPPSAWRWKSAQGKEPSGHLRRRDPTDPQLFFPTSEGGEMSSKRDGIPQSRQEHSVKTEPRDLFYWPRRTGQLQDSQHRPSAVHEGRTLAPPGRALPQNGSADDWVPDQGGPRRGNTTRRVRLKNPFYPLTQESYGAYAVMCLSVVIFGTGIIGNLAVMCIVCHNYYMRSISNSLLANLAFWDFLIIFFCLPLVIFHELTKKWLLEDFSCKIVPYIEVASLGVTTFTLCALCIDRFRAATNVQMYYEMIENCSSTTAKLAVIWVGALLLALPEVVLRQLSKEDLGFSGQAPAERCVIKISPDLPDTIYVLALTYDGARLWWYFGCYFCLPTLFTITCSLVTARKIRKAEKASTRGNKRQIHLESQMNCTVVALTILYGFCIIPENICNIVTAYMATGVSQQTMDLLNIISQFLLFFKSCVTPVLLFCLCRPFSRAFMECCCCCCEECIQKSSTVTSDDNDNEYTTELELSPFSTIRREMSTFASVGTHC
What is the function of this protein?
Receptor for the neuroprotective and glioprotective factor prosaposin.  Ligand binding induces endocytosis, followed by an ERK phosphorylation cascade (By similarity).
What are the official names of this protein?
Prosaposin receptor GPR37, G-protein coupled receptor 37.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PROA_THEYD
Sequence: MEIKQLVLNKAKEAKESSRFIAKASTDLKNKIIVRMADYLKQNKDELIKANRIDVENAQKKGISKALIDRLTLTEKRIDEMIKGLQEVVALPDPVGEITKMWLRPNGMQVGKMRVPIGVIGVIYEARPNVTVDVTGLCLKAGNSVVLRGGSEAINSNIALVKILKEALKDEGMHEGVVTYIDISQREAVLEMIKLEGIIDLIIPRGGEGLIRTVTENSRIPVLKHYKGVCHVFVDRDADLAMAEEICFNAKVQRPATCNAMETMLVDENIAKKFLPNMLKKFEDAGVELKGCLKTKKIYPKVKDVKEEDFYQEYLDLVLNVKVVKNIDEAIEHITKYGSAHSDSIVTKDYNKAMKFLKEVDSSAVFVNASTRLNDGYQFGLGAEIGISTDKIHARGPMGLEELTCTKFIVFGNGQIRQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTCA_PARPJ
Sequence: MNAPEILNGAATASPADATEATQTAARAKTPLTRREQKEAYENNKLFKRLARQVGEAIVDFNMIENGDKVMVCLSGGKDSYAMLEILMRLRERAPINFDIVAVNLDQKQPGFPEHVLPEYLKQLDIPFHIENQDTYSIVKRLVPEGKTTCSLCSRLRRGILYRVAGELGATKIALGHHRDDILQTLLLNMFYGGKLKGMPPKLQSDDGKNIVIRPLAYVKETDLEKYAELREFPIIPCNLCGSQPNLKRAEMKALVRDWEKRFPGRIENMFNALSNVVPSHLMDHKLFPFAGLRATGEADPQGDIAFDEEPCSTDAAEGAMPGATKSISIVQFDDL
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_AQUAE
Sequence: MEKIKVKIKGKEYEVEKGTPLGKIFELAGIKDALGGVINGKIIDLQTPVRESGEIKPVYRGSKESLEIMRHSLAHIMAQALKELYGAKKVHLGVGPTTEEGFYYDVEVEGHKITEEDLPKIEQKMKEIIERDYPILRRELSREEAIKLFDKLKEKYKIDIIKEIPEEEVISVYEQGDFIDLCKGPHLPSTGKAGAFKLTSISGAYWKGRSDQPQLTRIYGIAYWSDKEVKERLKFYEEVKKRDHRRLGKELEFFTIDDNVGAGLILWLPRGAIYRKVLEDYLREEHLKRGYQLVYTPHVGKSKLWETSGHLECYKQNMFPSMKIDEEEYYVKPMNCPFHIAIYKSRTRSYKELPLKLFELGTVYRYELSGVLHGLLRVRGFTQDDAHIVCTPEQVNDVIRETLDFALSTLKDFGFNEFKIYLSTRPEYSIGSDEQWEVSQNALKKAIEDLGYEYEIDEGGGAFYGPKIDVKIRDAIGRMWQLSTIQFDFNLPERFDMTYVGPDNKKHRPYMIHRALLGSIERFTGILLEHYAGLLPIWLSPTQVMIIPIADRHHEYAKKVYEFLKENGIRAEMDLREERMNAKIRDAELKKIPVILVVGDREAQNNTVSVRTKKEGNLGSMELNKFLDWIKEKIKNKE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.