PharMolix/UniProtQA huggingface dataset:
Protein: S15A1_HUMAN
Sequence: MGMSKSHSFFGYPLSIFFIVVNEFCERFSYYGMRAILILYFTNFISWDDNLSTAIYHTFVALCYLTPILGALIADSWLGKFKTIVSLSIVYTIGQAVTSVSSINDLTDHNHDGTPDSLPVHVVLSLIGLALIALGTGGIKPCVSAFGGDQFEEGQEKQRNRFFSIFYLAINAGSLLSTIITPMLRVQQCGIHSKQACYPLAFGVPAALMAVALIVFVLGSGMYKKFKPQGNIMGKVAKCIGFAIKNRFRHRSKAFPKREHWLDWAKEKYDERLISQIKMVTRVMFLYIPLPMFWALFDQQGSRWTLQATTMSGKIGALEIQPDQMQTVNAILIVIMVPIFDAVLYPLIAKCGFNFTSLKKMAVGMVLASMAFVVAAIVQVEIDKTLPVFPKGNEVQIKVLNIGNNTMNISLPGEMVTLGPMSQTNAFMTFDVNKLTRINISSPGSPVTAVTDDFKQGQRHTLLVWAPNHYQVVKDGLNQKPEKGENGIRFVNTFNELITITMSGKVYANISSYNASTYQFFPSGIKGFTISSTEIPPQCQPNFNTFYLEFGSAYTYIVQRKNDSCPEVKVFEDISANTVNMALQIPQYFLLTCGEVVFSVTGLEFSYSQAPSNMKSVLQAGWLLTVAVGNIIVLIVAGAGQFSKQWAEYILFAALLLVVCVIFAIMARFYTYINPAEIEAQFDEDEKKNRLEKSNPYFMSGANSQKQM
What is the function of this protein?
Electrogenic proton-coupled amino-acid transporter that transports oligopeptides of 2 to 4 amino acids with a preference for dipeptides.  Transports neutral and monovalently charged peptides with a proton to peptide stoichiometry of 1:1 or 2:1 (PubMed:7896779, PubMed:9835627, PubMed:8914574, PubMed:15521010, PubMed:18367661, PubMed:19685173) (By similarity).  Primarily responsible for the absorption of dietary di- and tripeptides from the small intestinal lumen (By similarity).  Mediates transepithelial transport of muramyl and N-formylated bacterial dipeptides contributing to recognition of pathogenic bacteria by the mucosal immune system (PubMed:9835627, PubMed:15521010).
What are the official names of this protein?
Solute carrier family 15 member 1, Intestinal H(+)/peptide cotransporter, Oligopeptide transporter, small intestine isoform, Peptide transporter 1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: CRTB_PARSN
Sequence: MSDLVLTSTEAITQGSQSFATAAKLMPPGIRDDTVMLYAWCRHADDVIDGQALGSRPEAVNDPQARLDGLRADTLAALQGDGPVTPPFAALRAVARRHDFPQAWPMDLIEGFAMDVEARDYRTLDDVLEYSYHVAGIVGVMMARVMGVRDDPVLDRACDLGLAFQLTNIARDVIDDARIGRCYLPGDWLDQAGARVDGPVPSPELYTVILRLLDAAELYYASARVGLADLPPRCAWSIAAALRIYRAIGLRIRKGGPEAYRQRISTSKAAKIGLLGIGGWDVARSRLPGAGVSRQGLWTRPHHA
What is the function of this protein?
Involved in the biosynthesis of carotenoids for the production of astaxanthin.  Catalyzes the condensation of two molecules of geranylgeranyl diphosphate (GGPP) to give prephytoene diphosphate (PPPP) and the subsequent rearrangement of the cyclopropylcarbinyl intermediate to yield 15-cis phytoene.
What are the official names of this protein?
15-cis-phytoene synthase, PSase.
What is the protein family that this protein belongs to?
Belongs to the phytoene/squalene synthase family.
Protein: RL27_PROM9
Sequence: MAHKKGTGSTRNGRDSNSKRLGVKAYGGEKVTAGSILIRQRGTSFLPGINVGKGKDDTLFALKEGTVSFESIKRNLRNRKRVNVVI
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: Y637_RICFE
Sequence: MLKKIIILFLGMFLLSACTDNFRSYFQRSANNRLVDSKGAKGGKRKPVYNNKYITLAKKNIVEDNLDDDNDDDDDYDSDSPLRGERIDPVKRNRDMYLKMIKRDIARQKAESGFAESDDDMTLNRANKKVRKDDSDKEKRMQEELNQIKAMLRETKRDISKYTCPNATVNQNYAPPVTNYEPVNYPPVKNSKPYNNNSKVKQKFIREDDDNGSNACSI
What are the official names of this protein?
Uncharacterized lipoprotein RF_0637.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: KTHY_CAUVC
Sequence: MTQGFFISFEGGEGAGKSTQIRRLADRLKAAGHDVIVTREPGGSPGAEAIRELLVNGAADRWSPVTESLLMYAARRDHIERVIRPGLARGAVVLCDRFADSTRAYQGAGGDAPASLIAALEEHVLGGTVPVLTLILDLPAEVGLQRAEARGGAARFESKGLAFHERLRAGYLEIARREPDRCVVIDADAELDAVTAAISDVVVQRLGL
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: ANMK_NITWN
Sequence: MMTAIGMMSGTSLDGVDVALIETDGERVTAFGPTGYRPYTNDERGLLREALAEAVNLTRRDARPGVIGMAEHAVTMAHSDAVTSFLARNGIRREDIDIVGFHGQTVLHRPGERLTVQIGDADALAKAIRVPVMHDFRAADVAAGGQGAPFVPAYHRALAQSLGRDGPICVVNIGGVSNVTYIDGADTLIACDTGPGNALLDDFMLRTTGEPFDRDGRLAQQGRPDADWIASALNHPFFALPPPKSLDRNDFASLALPDRPPADGAATLTAFTAAAIARIVPLLPKAPERWIVAGGGARNPIMLEMLREKVAPAPVERADALGWSIDAMEAQAFGYLAARGLKGLPLSYPATTGVPVPMTGGVVTRP
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: OTC_PYRHO
Sequence: MVVSLKGRDLLCLQDYTPEEIWTILETAKMFKIWQKIGKPHRLLEGKTLAMIFQKPSTRTRVSFEVAMAHLGGHALYLNAQDLQLRRGETIADTARVLSRYVDAIMARVYAHKDVEDLAKYASVPVINGLSDFSHPCQALADYMTIWEKKGTIKGVKVVYVGDGNNVCHSLMIAGTKLGADVVVATPEGYEPDKKVIKWAEQNAAESGGSFELLHDPVKAVKDADVIYTDVWASMGQEAEAEERRKIFRPFQVNKDLVKHAKSDYMFMHCLPAHRGEEVTDDVIDSPNSVVWDEAENRLHAQKAVLALLLGGVKTGF
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EMRK_ECOLI
Sequence: MEQINSNKKHSNRRKYFSLLAVVLFIAFSGAYAYWSMELEDMISTDDAYVTGNADPISAQVSGSVTVVNHKDTNYVRQGDILVSLDKTDATIALNKAKNNLANIVRQTNKLYLQDKQYSAEVASARIQYQQSLEDYNRRVPLAKQGVISKETLEHTKDTLISSKAALNAAIQAYKANKALVMNTPLNRQPQVVEAADATKEAWLALKRTDIKSPVTGYIAQRSVQVGETVSPGQSLMAVVPARQMWVNANFKETQLTDVRIGQSVNIISDLYGENVVFHGRVTGINMGTGNAFSLLPAQNATGNWIKIVQRVPVEVSLDPKELMEHPLRIGLSMTATIDTKNEDIAEMPELASTVTSMPAYTSKALVIDTSPIEKEISNIISHNGQL
What is the function of this protein?
Part of the tripartite efflux system EmrYK-TolC, which confers resistance to various drugs.
What are the official names of this protein?
Probable multidrug resistance protein EmrK.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein; Periplasmic side.
Protein: RS19_NANEQ
Sequence: MIFSTMAKEFRYKGYTLQELEQMSLEELAKIMPARQRRTLLRRLKFGWSDQQKKLFKKILLAKEGKYKKPIKTHARNTIILPFMVGVTVHVYNGKEYVPVQIKPEMIGHYLGEFSFTTKRPKHSAPGIGATRSSAHVSKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: SFSA_CAUVN
Sequence: MLLPQPLIHGRLVSRYKRFFADLVLDDGQEITAHCPNPGAMLGVKDAGQGAWVSWSDDPKRKLAYTLQMVEQGNALVGINTLLPNKLVAEALAADALPELSGYATIKPEVKYAEASRVDFLLTHPDRPPCWLEVKNCHFSRTPGLAEFPDCKAQRSTRHLEDLSAQVREGHRAVVLFVVQREDCETFSACAELDPAFAAGLEAAAKAGVEVLVYACEMGTQAVRIARRILWSHAHLTAI
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: PRM10_KLULA
Sequence: MSSSYGNNGDKNNHEKFGFNLLRKKPQQPSNRSERRADDSSSSEDEAGPSSNYVSSSQLNLPSFRPSGGSTDELNRANRTNVGSSDARYSPRTASNTESGNRRQQMIEDDAIATIRDNSGAARCFDDDDEEEEEHQEQKDSGENPADISPRTSGVTKKLQFKSHPSIIPEDTATQDGGEYYEEKDAEKEDQDDSVSTQSSESKMDHFRHLFRRRSTARPHQETNDGRNSAESHSKGGMRNLNGADDEVEDGGFLSKFLSLTGGGLTPAVNNTDPSGENDHERNAGQNNLEDPIPMSDIAATAQQIVQAHSMMAGKSAPGTQHGASGSASSEHPNGEHNLGTEAGVTSPFEPVSPFNQSTDGETMVSSHQDDAFYVPATNHYDDIDDPDDLEPLGIEGSYIAPVDRVRGGVLGSLLKLYQNQDDQYTKSQLSLNDSSIEQTPEPVDQAGKSDQKTGKKIYNPFHKHSKSQTNVSGANKSGSSMNLPNFKATRPKAAAKNLVKAKNFKKKAAAEARITVHIADLLQRQRFILRLCKALMLYGAPTHRLEEYMVMTSRVLEIDGQFLYVPGCMIISFGDMTTRTSEVQLVRCNQGLNLWKLHGVHSVYKQVVHDIMSVEDANMEIDRILTGKNLYPPWVSVLLYAFCSSMVTPFAFGGDWINMAVAFGIGLCVGSLQFIVSQKSNLYSNVFEVTASIVVSFCGRALGSIPNSNICFGATVQGSLALILPGYIILCGSLELQSRNLVAGAVRMFYAIIYSLFLGFGITLGAALFGWIYHDATNETSCSKNISPWFRFIFVPCFSIGLGLINQARWTQLPVMTLISCCGYVVTYFSGKHFANSTEFTSAMAAFVIGILGNLYSRIWKGFAVSAMLPAIFVQVPSGVASQSSLLAGVQSANAIVNNSTTTVVQDDLSGSMSFGVTMIQVSIGISVGLFASTLFIYPFGKKRTGLFTL
What are the official names of this protein?
Pheromone-regulated membrane protein 10.
What is the protein family that this protein belongs to?
Belongs to the ThrE exporter (TC 2.A.79) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PDXS_PARUW
Sequence: MGQFNQTEKGSFEIKVALAEMLKGGVIMDVTNSEQAKIAEDAGAVAVMALERIPSDIRVQGGIARMSNPELIQKIQETVSIPVMAKCRIGHFVEAQILESLQVDFIDESEVLTPADEENHIDKHIFKVPFVCGCRDLGEALRRIGEGAAMIRTKGEAGTGNVVEAVRHMRAINREIRHLMLMDSSELMAEAKRLGAPFHLVQMVAKSGVLPVPNFAAGGIATPADAALMMQLGAQSVFVGSGIFKSEDPAKRARAIVGATTFFQNPEKLAQFSMDLLDAMKGIDIRQLKREDLMAQRGW
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: MIAB_RICFE
Sequence: MSKKLYIKTYGCQMNVYDSVKMQDLLYPFGYEPTENIEDADVIILITCHIREKAAEKTYSELGRIKKLQDTRKKQGLNSAIIVVAGCVAQAEGEEIFSRAPYVDIVVGPQSYYNLPELISKVVRHEKHLIDLDFVEEAKFDNLPEQLYPQGASSFISVQEGCDKFCTFCVVPYTRGAEFSRNVEQVYREALKVVSSGAKEITLLGQNVNAYHGKGPDDKIFTLADLLGHLAQIPNLERLRYMTSHPIDMTDDLIKLHGTEPKLMPFLHLPVQSGSNKILKAMNRKHDRDYYFDIINRLRETRPDIVLSSDFIVGFPGETDEDFEDTLDLVRRVKYGQCYSFKYSPRPGTPGATRTDQVPEHIKSERLTILQQELTAQQLAFNESCVGSIMKVLFDRNGKFDDQIIGKTPYMQSVYIQNPNKSLLGKITDVKITKAASNSLTGEVI
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSY3_PECAS
Sequence: MAKAATTLKTASVLAFERKLANSDALMYAGNWAQQDNWTAIAIQEKSVRGTISNRLKNALTSDPAKLDAEIQKANLQKVDVAALPFGADTLKIVFTLRVLGNLAQPSVCNDQDYQTALGDIITGYAQEQGFSTLAARYAENIANGRFLWRNRVGAEAIRVVVTKKGERSWEFNGEDYSLRQFSQPAGDLAALTQAIEKGLAGDASALFTVEAYVQLGNGQEVFPSQELVLDEKARNGKSKILYQVNDVAAIHSQKIGNALRTIDDWYPAADEAGPIAVEPYGSVTSRGKAYRQPREKMDFYTLLDNWVIKGDVPMPEQQHYVIATLIRGGVFGEKGE
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
What are the official names of this protein?
CRISPR-associated protein Csy3.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated Csy3 family.
Protein: MRAY_SOLM1
Sequence: MIYYLLVPLVAHFSALNVFRYITFRSIAALLTALVLSIVFGPKFIDWLRRLKFGQYIHEDVAAHKQKAGTPTMGGLLIAFCIVVSVLLWGDLANEYVWMTLFVFLGFGALGYVDDHAKVVRKQNKGLTPKQKLLGQIVVSGVAAALLVLDPEYSTRLAVPFFKHLTPDLGLWYLPFAMLVMIGASNAVNLTDGLDGLAIGPMIVNAAMFGLFIYVAGHAQMARYLQVMPVSGVGEVTVFCGALVGAGLGFLWFNAYPAQIFMGDVGSLSLGGALGFLAVLCKQELLLIVVGGLYVAETVSVILQVGYFKMTGGKRIFRMAPLHHHFELMGVPESKIIIRFWILSILLALVGLSTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYY_STRZP
Sequence: MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSLHLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQGQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIETGISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVITVPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDEIEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKELKQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQELDYVLSDADKLENELTVIRRGKKKYFVLTY
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GGGPS_PICTO
Sequence: MTVYNDIIEKLKRKKIHMTLIDPASQDIESSGRIAEAAERAGTDFIMIGGSTRINSELMDKTIGAIKSKTSLKTIIFPGSPEMISPRADAIYYMSLMNSRNIDFIIGHQVKTSLFLRQLAIETIPMAYLIFEPGMTVGRVGEANLIKRDDSDTALLYALAAETFGMKLVYLESGSGSPTYVSENVIKKIKEYVKIPVIVGGGIRDKNAAEKLAAAGADIIVTGTIVERSRNVYEALQEIISSI
What is the function of this protein?
Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).  This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
Geranylgeranylglyceryl phosphate synthase, GGGP synthase, GGGPS, (S)-3-O-geranylgeranylglyceryl phosphate synthase, Phosphoglycerol geranylgeranyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GGGP/HepGP synthase family. Group II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF76_MAIZE
Sequence: MKKILFSMFYSILVGEEPDSVFLKKEGKQNQVKMIWIAPSSCAKDLTISEGTGATFPFHFHSRVSICFHALFLRPRNMKWTNSFS
What are the official names of this protein?
Uncharacterized protein ycf76, ORF85.
What is the protein family that this protein belongs to?
Belongs to the ycf76 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ICP1_ENTH1
Sequence: MSLTEDNNNTTITIAKGENKEIILHGNPTTGYSWVVDSCEGLSNTVEYVADQHAPGICGCGGKYHIKITGTQTGEGKIVLVYRRPWAPNANDRTFTLKVNVQ
What is the function of this protein?
Cysteine protease inhibitor (PubMed:15757643, PubMed:16979632, PubMed:21440496, PubMed:32731033).  Inhibits cysteine proteases CP1, CP2 and CP5 (PubMed:16979632).  May protect the cytosol against cysteine proteases released by damaged intracellular vesicles (Probable).
What are the official names of this protein?
Amoebiasin-1, Cysteine protease inhibitor 1, EhICP1, ICP-1.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I42 family.
Protein: TF2LX_MACMU
Sequence: MEAAADGPAETRSRVEKDSRRAIKDSPAKTQSPAQDTSIMLRNNADTGKVPALPEHKKKRKGYSPAESVKILRDWMYKHRFRAYPSEAEKRMLSKKTNLSLSQISNWFINARRRILPDMLQRRGNDPIVGHKTGKDAHATHLRSTDASVPAKSGPRGSDNVQSLPLRSSPKGQMSGEKIPEPGSAPSQKLTMIAQPKKKVKVSNITSLSSPEPVSTEEYADFSSFQLLVDAAVQRAAELELEKKQESNP
What is the function of this protein?
May have a transcription role in testis.
What are the official names of this protein?
Homeobox protein TGIF2LX, TGF-beta-induced transcription factor 2-like protein, TGFB-induced factor 2-like protein, X-linked, TGIF-like on the X.
What is the protein family that this protein belongs to?
Belongs to the TALE/TGIF homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL1_DESPS
Sequence: MPKRGKNYSNKSQSFDKQQVYTLEEAVGHVLATSYAKFDETFDIAIKLGVDPRHADQMIRSSVVLPHGTGKVTRVLVFAKGAKEAEAREAGADFVGGDDLVEKIQGGWLEFDKTVATPDMMGTVGKIGRVLGPRNLMPNAKLGTVTFDVAKVIEEIKSGKVDFKVEKAGILHAGIGKISFGNEKLTANALAFIEKIIQLKPSSSKGVYLKSVTISSTMGPGVKVDPVYLRALVKK
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: NADO1_ORYSJ
Sequence: MATIPEVPASELIQTMPRVGMGTAAFPFTSSEDTTAAMLRAIELGYRHFDTARIYATEGCVGEAVAEAVRRGLIASRADVFVTSKIWCSDLHAGRVVPAARETLRNLGMDYVDLLLVHWPVSLTPGNYDFPFPKEVILPSFDMEGVWRGMEECHRLGLARAIGVSNFSAKKLEQLLSLAAVRPAVNQVEVNPMWQQRTLREVCRREGVQLCGYSPLGAKGTPWGSAAVMDSGVLQEIAGAKGKTLAQICLRWLYEQGDVLLVKTYNEKRMKENLDIFNWELTDEERERISQLPQLRGLPGLEFISDHGPYKSVEDLWDGDV
What is the function of this protein?
May play a role in auxin-induced cell growth by generating hydroxyl radicals, which tends to increase cell wall loosening.
What are the official names of this protein?
Probable NAD(P)H-dependent oxidoreductase 1.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
Protein: TOP1_SYNY3
Sequence: MSKLVIVESPTKARTIRNYLPQDYRVEASMGHVRDLPASAEEVPAAYKDKSWANLGVNVEDHFSPLYVIPKSKKKVVKELQTALKNADEVILATDEDREGESISWHLLQLLQPKVPIKRMVFHEITQEAIRSALENCRDIDENLVHAQETRRILDRLVGYTLSPLLWKKIAWGLSAGRVQSVAVRLIVQRERARRAFKTAGYWDLKAELEQNKNPFQAKLMTLGGTKLANGSDFDPNTGALLPDKQVVVLDEAQAIALKERLTGKPWAVVNTEEKPGVRKPSPPFTTSTLQQEANRKLGISARDTMRVAQKLYEEGYITYMRTDSVHLSDQAVTAARNCVQQMYGKEYLSPQPKQYTTKSKGAQEAHEAIRPAGTEFRIPNQTGLKDRELALYELIWKRTVACQMADARITQLSVLLKVEDAEFRAAGKRIDFPGYFRAYVEGSDDPDAALENQEVILPPLKVGDRPNCREIDTVGHETQPPARYTEASLVKTLESEGVGRPSTYASIIGTIIDRGYVQMRSKALTPTFTAFAVVSLLESHFPDLVDTGFTSRMEQKLDEIAIGKTQWLPYLQGFFLGESGLENQVKVRQDQIDPAIAKAIELENLAAKVKIGKFGPYIEIPQGEEIITASIPQDLTPADLNPEQVAVLLKQKTEGPDKVGIHPETGEPIFILIGAYGPYVQLGEATEENKKPKRTSLPKGVKPEDVTLEMAVGLLALPRNLGEHPESGKNIKASLGRFGPYVVHDQGKDGKDYRSLKGDDDVLTITLERALELLAEPKRGRGSRTPLKQLGLHPEDQEPVNLFKGPYGVYIKHGKVNASLPEGETEETITLEKALPLLAEKAGSGKKTSRKKATTTAKGTKKTTSKKASATGTAKKTTTKRTTRKKAASPDQSSEAG
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.  The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils.  Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.
What are the official names of this protein?
DNA topoisomerase 1, DNA topoisomerase I, Omega-protein, Relaxing enzyme, Swivelase, Untwisting enzyme.
What is the protein family that this protein belongs to?
Belongs to the type IA topoisomerase family.
Protein: LEP_STAAR
Sequence: MKKELLEWIISIAVAFVILFIVGKFIVTPYTIKGESMDPTLKDGERVAVNIIGYKTGGLEKGNVVVFHANKNDDYVKRVIGVPGDKVEYKNDTLYVNGKKQDEPYLNYNLKHKQGDYITGTFQVKDLPNANPKSNVIPKGKYLVLGDNREVSKDSRAFGLIDEDQIVGKVSFRFWPFSEFKYNFNPENTKN
What is the function of this protein?
Essential for cell viability.
What are the official names of this protein?
Signal peptidase IB, SPase IB, Leader peptidase IB.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: GATB_COREF
Sequence: MTAAFYDLMDFDEVLEKYDPVMGLEVHVELATETKMFSASSAHFGAAPNSNVDPVSLGLPGALPVVNAKGVEWAIKIGLALNCSIAESSRFARKNYFYPDQPKNYQISQYDEPIAYDGYLDVMLEDGTEWRIEIERAHMEEDTGKLTHLGGTSGRIHGATASLVDCNRAGVPLIEIVTKPIEGAGARAPEIAKAYVSALRDLVKALGVSDGRLDQGSMRVDANLSLRPIGQEEFGTRTETKNINSLKSVEQAITFEMQRQAHVLDNGGTIDQETRHYQETDGTTSKGRPKETAEDYRYFNDPDLPPVIAPAEWVEEIRATLPELPWVRRARIQEEWKLSDAEMRDLVNANALDLIIETVEAGTTPDEARAWWVSYLSQKANETGVELEALPVTPAHVARVVALIKEGKLTNKLGRQAIDGVLAGEGDVDAVVASRGLEVVRDDGAIEAAVDEALAANPDIVEKYRAGNTKVTGAIVGAVMKATRGKADPAQVNKLIAEKLA
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: RAD50_DROME
Sequence: MSSIESLSIQGIRSFGTYADDLQSIKFSSPVTLILGENGCGKTTVVECLKYALTGECPPGSDRGKSFVHDPKIFGLNEVLAQIKMQVRDRRGAQVSICRTMKVSKKRNKMSFETMDSTINFLTGAGQSKREKQDSLSGRSVDIDVAISDFMGVSKAIINNVLFCHQEDSSWPLDESKKLKEKFDAIFGITEYNKALDKIIKLRKEAMEELKIKEANIKHVAYLKQEMEVKTLNLQKAQRKCDAIKAQCSECEEEMKPIEARLVEIRNVEFEIGKYQAQKVEMDTKHKNCKDQISTLTLKIKKPFRGTLDELDQEISNFDQRMLEMRQKRTEVEGDLSQIKRSSVAEQEKLGTQDRKHCLAKQRHQSELACRAQLLKRVKEFCRELHIPIDCDLVEQPEKMGEVLRDIEAMIITKHCEITEIVEQNEKADRSRQVKIDELRIELTKSEQSVTAQEKQRESSKRESETLGVEIKKIETSMQDLKKLEKEINEVNELYESATKNIDQQAIKDAIARKKASIAENQIQFKKLDEQLTFLGSMAKLVAECSLKQKELDKKNQEVHRVRSRHSDHFGKLFKEPITCNYRRSMQVVYEKLRREIQELNEKANTQKLKEQSYEIKRKNLISDISRMEKELKDSEELIYQKCRSTPYDDLLERSKTTISKLQFDHGALKSSEALYKKYIQKMDEEPSCPLCHHNMTSDEACDLTSELTDEIQKLPDNITRAEKALKAEQIKYENLLQLKPTILKVKELKDSLPQKKEELKKVEELLGDSVSEYETLIALIGEPTHNMELANSMMGDMSLLDEALKDSARLTKDLDLQKGQLPASYDSSVSMDDLQAEKSKVSKELETERKELESAQNAVQQQMDALNRLREKKNSLKDRQIHLREGLQSLPQLKERLEKLNSFLTTVASEISELKAKIQPLKLNLRAAIEEKERLKKSESEKLAQLNSKYNSYKSTDHDIQRLNKEAEDYAKLDLRNEIKKLDEIIMASKDKLRKLEAEISLKTDELETIKTECSNQQTVERDLKDNRELKQLEDKEAKLRESCQVLDKQLGNLDFHSVSKEKVNLTKQRDKATVRKGELLGQLGEIHSQVNKLQREIDEPRFKESLKNFRKANYEIEVTRLCIEDLGQYRLALEWALIQFHSEKMEMINRLIREYWRKIYRGNDIDYIQVKTDEVSSDASADRRKTYNYRVVQSKNYSEIEMRGRCSAGQRVLASLIIRLALAETFSSNCGVLALDEPTTNLDRANINSLCEALNCIVEERQSQSNFMLIIITHDENFVSSLGKITSYHRVFRNEECKSVIRRVEAGPSKKALIDQ
What is the function of this protein?
Essential component of the MRN complex, a complex that possesses single-stranded DNA endonuclease and 3' to 5' exonuclease activities, and plays a central role in double-strand break (DSB) repair.  The complex participates in processes such as DNA recombination, DNA repair, genome stability, telomere integrity and meiosis.  The MRN complex may protect telomeres by facilitating recruitment of HOAP and HP1 at chromosome ends.  In the complex, it mediates the ATP-binding and is probably required to bind DNA ends and hold them in close proximity.
What are the official names of this protein?
DNA repair protein RAD50.
What is the protein family that this protein belongs to?
Belongs to the SMC family. RAD50 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Chromosome, telomere. Note=Uniformly distributed along mitotic chromosomes.