PharMolix/UniProtQA huggingface dataset:
Protein: APU_THETY
Sequence: MFKRRALGFLLAFLLVFTAVFGSMPMEFAKAETDTAPAIANVVGNFQSKLGDSDWNINSDKTIMTYKGNGFYEFTTPVALPAGDYEYKVALNHSWEGGGVPSQGNLSFHLDSDSVVTFYYNYNTSSITDSTKYTPIPEDKLPRLVGTIQPAIGAGDDWKPETSTAIMRDYKFNNVYEYTANVPKGNYEFKVTLGPSWDINYGLNGEQNGPNIPLNVAYDTKITFYYDSVSHNIWTDYNPPLTGPDNNIYYDDLRHDTHDPFFRSPFGAIKTGDTVTLRIQAKNHDIESAKISYWDDIKKTRIEVPMYRIGQSPDGKYEYWEVKLSFDHPTRIWYYFILKDGTKTAYYGDNDEQLGGVGKATDTENKDFELTVYDKNLDTPDWMKGSVMYQIFPDRFFNGDSSNDHLKKYSRGFDPVEYHSNWYELPDNPNDKNKLGYTGDGIWSNDFFGGDLKGIDDKLDYLKSLGISVIYLNPIFQSPSNHRYDTTDYTKIDELLGDLSTFKKLMEDAHAKGIKVILDGVFNHTSDDSIYFDRYGKYLNTGVLGAYQAWKQGDQSKSPYGDWYEIKPDGTYEGWWGFDSLPVIRQINGSEYNVKSWADFIINNPNAISKYWLNPDGDKNVGADGWRLDVANEVAHDFWVHFRGAINTVKPNAPMVAENWNDASLDLLGDSFNSVMNYLFRNAVIDFILDKSFDDGNVVHNPIDAAKLDQRLMSIYERYPLPVFYSTMNLLGSHDTMRILTVFGYNSADENQNSQAAKDLAVKRLKLAAILQMGYPGMPSIYYGDEAGQSGGKDPDNRRTFPWGREDTDLQTFFKKVVNIRNENQVLKTGDLETLYANGDVYAFGRRIINGKDTFGKSYPDSVAIVVINKGDAKQVSIDTTKFIRDGVAFTDALSGKTYTVQDGKIVVEVGSMDGAILISDTGQNLTAPQPITDLKAVSGNGKVDLSWSVVDKAVSYNIYRSTVKGGLYEKIASNVTQITYTDTEVTNGLKYVYAVTAVDNDGNESALSNEVEAYPAFPIGWAGNMNQVNTHVIGVNNPVEVYAEVWAQGLTDKPGQGENMIAQLGYRYIGDTVGDAVYNAVYNKVEGVEISKDWTWVDAQYVGDSGNNDKYMAKFVPDMVGTWEYIMRFSSNQGHDWTYTKGPDGKTDEAKQFTVVPSNDVETPTAPVLQQPGIESSRVTLNWSPSADDVAIFGYEIYKSSSETGPFIKIATVSDSVYNYVDTDVVNGNVYYYKVVAVDTSYNRTASNTVKATPDIIPIKVTFNVTIPDYTPDDGVNIAGNFPDAFWNPNANQMTKAGSNTYSITLTLNEGTQIEYKYARGSWDKVEKGEYGNEIDNRKITVVNQGSNTMVVNDTVQRWRDVPIYIYSPKDKTIVDANTSEIEIKGNTYKGAKVTINDESFVQQENGVFTKVVPLEYGVNTIKIHVEPSGDKNNELTKDITITVTREKPARRQNLLLLHQQKQQNHLKKYHKAK
What are the official names of this protein?
Amylopullulanase, Alpha-amylase/pullulanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: HIS7_NITOC
Sequence: MSNYTATVYRETLETRVEVDLNLSGEGHFTAETGLPFLEHMLAQVARHGLLDLTVKASGDLHIDAHHTVEDIGITLGQALQQALGDKTGLQRYGYAYVPLDEALSRVVLDLSGRPSLHYRVNYPRARIGDFDVDLFQEFFQGLVNHAAMTLHIDNLHGRNAHHIAETIFKAFGRALRVAVEYDPRRKGQLASTKGML
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VAPC2_METJA
Sequence: MRRLKMEENKIFFDSNILIYHLCGKVEAKKLIEKVENKEICGFINPIVISEVLFFYIRATTNKRHYDIKKHPEILKSLDLDIVFELFSIFQILDLNSEIVKISREIIKKYCLLPNDALICSTCKFYKINKICSFDDDFKRVDFLEIIEI
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  An RNase.  Its cognate antitoxin is VapB2 (By similarity).
What are the official names of this protein?
Ribonuclease VapC2, RNase VapC2, Putative toxin VapC2.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: LNT_AGRRK
Sequence: MERLSGKVILVWGFKRALLAILAGAIGVLALPPFGFFAAMFVSFTLLVWLLDGAAAGPDSGFLGRLWPAFTTGWLFGFGYFVAGLWWLGHALLIDADQFAWALPLAILGLPAFLAIFYGVAAVLARLLWSDGMGRIAALAFGFGLLEWLRSFLFTGFPWNAIGYGAMPIPLMMQSAHVIGVLGVTVLAVFVFAAPALLGTRQGRVPGIGLAVLIAAAHFAYGYYALNLPALPPAAGKAAPVVRIVQPAIDQEAKMDTAADRNAIFDKHLSLSVQPPVNGGKRPDIIVWPETAIPFILTDNQDALTRIADQLDDDQILITGAVRVEDMGPGVEPRYYNSVYVIDGRGQIIGASDKTHLVPFGEYVPFENILGYLGIENVVELPGGFSAAASRQLLTLPDGIKLYPLICYEIIFPNEMTPEIRQADAILNVTNDAWFGDTPGPYQHFLQARVRAVEQGLPLIRSANTGVSAYVDAHGRLISGIDFNEQGFVDSTLSGATVSRIDDSVRKTYFWLIIGIVGMIAVISRMGFISRVN
What is the function of this protein?
Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
What are the official names of this protein?
Apolipoprotein N-acyltransferase, ALP N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KGD_MYCSS
Sequence: MSSSPSPFGQNEWLVEEMYRKFREDPSSVDPSWHEFLVDYNPEPTTDSSASENGQQTRTAAPKAPPEPAPAPAPKTPDSKTPDSKSQAPKQDSKPQESKPQAKAKPAESKSSTKPADAKSEKSGKSGTNGAAKPAAQPADDSDQNQVLRGAAAAVAKNMSASLDVPTATSVRAIPAKLMIDNRVVINNHLKRTRGGKISFTHLIGYAIVAAVKKFPNMNRHFAEVDGKPNAVTPAHTNLGLAIDLQGKDGNRQLVVAAIKKADTMRFGQFIAAYEDIVRRARDGKLTAEDFSGVTISLTNPGTIGTVHSVPRLMRGQGAIIGVGAMEYPAEFQGASEERIADLGIGKLITLTSTYDHRIIQGAESGDFLRTVHQLLLSDDFFDEIFRELGIPYEPVRWRTDNPDSIEDKNARVIELIAAYRNRGHLMADIDPLRLDSNRFRSHPDLDVLTHGLTLWDLDREFKVNGFAGAERKKLRDVLAVLRDAYCRHIGVEYTHILEPEQQQWLQERIEGKHEKPTVAQQKYILSRLNAAEAFETFLQTKYVGQKRFSLEGAETVIPAMDAVIDQCAEHALDEVVIGMPHRGRLNVLANIVGKPYSQIFSEFEGNLNPSQAHGSGDVKYHLGSSGTYLQMFGDNDITVSLTANPSHLEAVDPVMEGLVRAKQDLLDKGDTEDGYTVVPLMLHGDAAFAGQGVVAETLNLALLRGYRTGGTIHLIVNNQIGFTTSPAAAKSSEYCTDVAKMIGAPIFHVNGDDPEAAVWVSRLAVDFRQKFKKDVVIDLLCYRRRGHNEGDDPSMTQPSMYDVIDTKRGVRKSYTEALIGRGDISMKEAEDALRDYQGQLEQVFNEVRELEKHEIEPSESVEADQQIPAKLATAVDKSLLARIGDAHLAVPEGFTVHPRVKPVLEKRREMAYEGKVDWAFAELLALGTMISEGKLVRLSGQDTRRGTFTQRHSVVIDRKTGKEFTPLQLLATDSDGNPTGGKFLVYDSPLSEFAAVGFEYGYSVGNPDAMVLWEAQFGDFINGAQSIIDEFISSGEAKWGQLSDVVLLLPHGHEGQGPDHTSGRIERFLQLWAEGSMTIALPSTPANYFHLLRRHSLDGIQRPLIVFTPKSMLRNKAAVSDIRDFTEQKFRSVLEEPTYTDGDGDRNKVTRILLTSGKIYYELVARKNKESRDDVAIVRIEQLAPLPKRRLAETLDKYPNVEEKFWVQEEPANQGAWPTFGLTLPEMLPDHFTGIKRISRRAMSAPSSGSSKVHAVEQQEILDEAFAP
What is the function of this protein?
Shows three enzymatic activities that share a first common step, the attack of thiamine-PP on 2-oxoglutarate (alpha-ketoglutarate, KG), leading to the formation of an enamine-thiamine-PP intermediate upon decarboxylation.  Thus, displays KGD activity, catalyzing the decarboxylation from five-carbon 2-oxoglutarate to four-carbon succinate semialdehyde (SSA).  Also catalyzes C-C bond formation between the activated aldehyde formed after decarboxylation of alpha-ketoglutarate and the carbonyl of glyoxylate (GLX), to yield 2-hydroxy-3-oxoadipate (HOA), which spontaneously decarboxylates to form 5-hydroxylevulinate (HLA).  And is also a component of the 2-oxoglutarate dehydrogenase (ODH) complex, that catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2).  The KG decarboxylase and KG dehydrogenase reactions provide two alternative, tightly regulated, pathways connecting the oxidative and reductive branches of the TCA cycle (By similarity).
What are the official names of this protein?
Multifunctional 2-oxoglutarate metabolism enzyme, 2-hydroxy-3-oxoadipate synthase, HOA synthase, HOAS, 2-oxoglutarate carboxy-lyase, 2-oxoglutarate decarboxylase, Alpha-ketoglutarate decarboxylase, KG decarboxylase, KGD, Alpha-ketoglutarate-glyoxylate carboligase.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoacid dehydrogenase family. Kgd subfamily.
Protein: RLMKL_HISS2
Sequence: MKQLFATTSRGFEELLKVELTDLGAQECRVVQGGVHFIANDETQYRILLWSRLSSRILLPLITTKIYSDLDLYSAIVGQNWLTHFDERVTFLVDFNGTNREIRHTQFGAMRVKDGIVDYFERHGKTRPNVDKEYPDIRIHAYLNQDELVVSLDLSGEALHLRGYREDTGKAPLRETLAAAIVLRSSWEKGTPLVDPMCGSGTLLIEAAQMEAQIAPQLHRLHWGFDFWKGHNQVVWEKVKQEAVELAEQAFNRKLTPHFWGFDLDHRVLKKAQKNAQNAGVSHLIKWQQGDVAGLKNPTEQEIGTVICNPPYGERLGTTPALIALYSVFGRQLKTEFADWNVSIFSGEPALLDCLRLRAYRQFKAKNGPLDCVQKNYHIAVRKQVESAVENSQEKTLTFVSENTQVAQDFANRLRKNIKKIDKWANQQKLDAYRLYDADLPEYNLAVDRYADHIIVQEYAAPKNVDENKARQRLLDAVSAILSVTGIETNKLILKVRQKQKGTSQYEKLANKGEYFYVHEYGAKLWVNLTDYLDTGLFLDHRLTRKMLGEMAVGKDFLNLFAYTGSATVHAALGLAKSTTTVDMSNTYLNWAEQNLLLNDIEGKQHKLIQADCLQWLNKCDRQFDLIFVDPPTFSNSKRMEDSWDVQRDHIKLMANLKRILRTNGTIVFSNNKRGFKMDIDGLQELELSAVEISAKTLPLDFERNKQIHNCWIIRHQS
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: USPB_ECO45
Sequence: MISTVALFWALCVVCIVNMARYFSSLRALLVVLRNCDPLLYQYVDGGGFFTSHGQPNKQVRLVWYIYAQRYRDHHDDEFIRRCERVRRQFILTSALCGLVVVSLIALMIWH
What are the official names of this protein?
Universal stress protein B.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RSMJ_PHOPR
Sequence: MQLALICENPERQNELDELAQRWGLSHDENSIFALVLTDTQLELRKLDEAKLGAVFVDLVSGAAAHRRKFGGGRGQAIAKAVGLKKGVMPRVLDGTAGLGRDAFVLASLGCTVQMVERHPVVAALLDDGLARAKQDPEIGGWITERLSLLHASSQDALVKLLEDPDFIAPDVVYLDPMYPHKKKSALVKKEMRVFQTLVGADNDADSLFAPAMALATKRVVVKRPDYAEFLANAKPSTAIETKKNRFDVYVKAAMT
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y284_PYRHO
Sequence: MTRRVKTGIPGVDEILHGGIPERNVVLLSGGPGTGKTIFSQQFLWNGLKMGEPGIYVALEEHPVQVRQNMAQFGWDVKPYEEKGMFAMVDAFTAGIGKSKEYEKYIVHDLTDIREFIEVLRQAIRDINAKRVVVDSVTTLYINKPAMARSIILQLKRVLAGTGCTSIFVSQVSVGERGFGGPGVEHGVDGIIRLDLDEIDGELKRSLIVWKMRGTSHSMRRHPFDITDKGIIVYPDKVLKRGKVLEL
What are the official names of this protein?
UPF0273 protein PH0284.
What is the protein family that this protein belongs to?
Belongs to the UPF0273 family.
Protein: UVRC_RICTY
Sequence: MSLEISGRELIKSKIIDAPECSGVYKMLDVSKQVIYVGKAKILKKRLTNYIKSDLDNKTLRMIANTYFLEYIITHSEVEALLLEAQLIKKFQPKFNILLKDDKSFPFIKLSLDHDFPQLLKYRGKALSDGKLFGPFASNTQVNTTLTELQKIFKLRSCTDNYFNSRTRPCLQYEIKRCYAPCVGKINKENYRVLVIQVKDFLQCRTRELQENLSKKMQELSSQMRFEEAAEIRDRIKALSYVQLKSRILDVVKNADIISIVHKDLHYCIEVALYRAGQPYGNIPYFFSSTENSTHEEVLEYFLLQFYQKQQVPSEIIMNHEINSKENVIEAIKKINNISDLSIIVPHKGDKAKLVHKAEVNALFSLEQYLKKITKNTEIMFEVKKLFDLPEIPERIEIYDNSHIQGMFAVGVMVVAGKIGFDKKEYRVFSLSSRNFTIGSEIELRDDIKGDDYGMLRQVLTRRFTRLKNEPNKLPSLMIIDGGKGHLTVVKEVMDKFGMNIPFVCMSKGRDRNAGLEQLHMQGKEVFTLDKNLLVMKYLQILRDEAHNFAIKNHRLGRSRAIKISSLDDIDGVGEARKTALLHYFGSYKAVCNATIDELAKVKGISKSLASMIFNVLNRKISLDNS
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LGT_PSESM
Sequence: MLPYPQIDPVAVAIGPLQIHWYGLMYLVGIGGAWLLASRRLNKFDPTWTKEKLSDLIFWLAMGVIVGGRLGYVLFYDLSAYIANPLLIFEVWKGGMAFHGGFVGVMIAAWWFGKRNGKSFFQLMDFVAPLVPIGLGAGRIGNFINAELWGKPTDVPWAMVFPPFSDPAQLARHPSQLYQFALEGVALFIILNLYARKPRPTMAVSGMFALFYGIFRFVVEFVRVPDAQLGYLAWGWVTMGQILSLPMIIAGLFLIWLAYKRDPAASKAAV
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS1_BACC1
Sequence: MRNIQIALTKGRLEKHVIPLFEQIGIDCSELKNKGRKLVFQSKNTDISFILVKAVDVATYVEHGVADIGVVGKDVLMENEKDIYEMLDLGVGVCKFCVASIPTYNPKSYRKKRIATKYPHITSNYFHDKGEDVEIIKIEGSVEIAPILGLVDAIVDIVETGKTLQENGLIVFEEMYSISARMIVNKAALKTKKDEIFSIINVMEQEILSGK
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP8_RHIUN
Sequence: MPQLDTSTWFITITSMTITLFIMFQLKLSKHSYPSNPELKPINTSMHTTPWESKWTKIYSPLSLPQQ
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: HSS2_SENVE
Sequence: MAESNKEAIDSARSNVFKESESLEGTCAKIGGYDFNNGIDHSKLLKSMVSTGFQASNLGDAMIITNQMLEWRLSHDEVPEHCSEEEKKNRESVKCKIFLGFTSNLISSGVRETICYLAQHRMVDVLVTTTGGIEEDFIKCLASTYKGKFSLPGADLRSKGLNRIGNLIVPNDNYIKFEDWIIPIFDQMLIEQKTQNVLWTPSRMIARLGKEINNETSYLYWAYKNNIPVFCPSITDGSIGDMLYFHSVSNPGPGLVVDIVQDVIAMDNEAVHASPQKTGIIILGGGLPKHHICNANMMRNGADFAVFINTAQEYDGSDSGARPDEAVSWGKISSTGKAVKVHCDATIAFPLLVAETFAVKKEKASKVNGF
What is the function of this protein?
Catalyzes the transfer of an aminobutyl unit from spermidine onto putrescine.  The resulting polyamine homospermidine is a precursor in the biosynthesis of pyrrolizidine alkaloids.
What are the official names of this protein?
Homospermidine synthase 2, HSS2.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine synthase family.
Protein: PEP3_SCHPO
Sequence: MSLAEDWIDPNSSEDSDIQEDAELEYTADNPEKEQRGVFSLEKVQLQFPVSIRCLAVENNILVMALTSDKLMIVDLERPEDIIDIELPKKVLALGLTYKIFLDPSGHYIFVTTTAGDNCLFTPSHQGRVLTKLKGHTVEAVQWNLNGGNILELLIASKSGVLLELVLTLDSANLKRIEKSINTLYSFPFMESPMGILKNIQDDSMTIVTNKRILRFEPKTSRGKDQLYFSPAFQGSMKEILSFSEEETAQCFSYSPFPKNLAEPYTLALKTSKRIIYLDIMNPVNPDIQDYEFNESPKLSVPTVEMNMILTSFHLAFLDLDTLYIVNRVNGKESYQQRVNLSPHEEILGLCCDHEKNTYWLYTTDSLHELVVNNETREASLVFLEKGDFEKALECANTAKVRNTVLVGYAEFLMEHEEYERAATLYAETLKSVEEVALKFIELNQKDVLRLYLWKKLRSYKSTMKIQKSLLVNWLLELMLAKLNSLDEKERLELFPENVMQQRQQVQREFSTLLNQYKDEINREAAYNLANNYGKEEQLLQIATVMKDQSYIMHYWVQRENYEKALETLNEGVSQETLIQHATALLTHRPNETVSIWERQTDLDVHALIPSLLSYNQRSHVPVEENAAIRYLRYVTGVLGCVDPSIHNTLFCIYACHSSSNESYLMNYIEQQGNHPLYDMDLGIRLCLQFNCRRSAVKILVLMKLYSQGVELALEADDCELAATIANIPEEDVVLKKTLWQTIAKYMFSKKSGIKETLRFLENSEVLQLPELIRLLPEDIKLDDLSDNVCDELDHCMKRIEQLDFEIGQASEVAHEIQTNAENMRNRYIVLEPNESCWHCNQPLFSEPFVLFPCQHAFHRSCMLEKTYKLASEKNILKECQLCGPSYAVRLINEPFSTDF
What is the function of this protein?
Required for vacuolar biogenesis.
What are the official names of this protein?
Vacuolar membrane protein pep3, Vacuolar protein sorting-associated protein 18.
What is the protein family that this protein belongs to?
Belongs to the VPS18 family.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ALG13_CRYNB
Sequence: MAHPFTLLVTVGSTLFPSLTSHVLLPTFLSLLQSLGVQRLVVQYGRAELKLQDDVKQTLNIDSQGDGIGVWSDNDGDRVRDEKQNGMVVEVMRFTNDFEGLVGKSDAVISHAGSGSILTVLRRAPPIPLLVVPNRSLMDDHQSELADALYKDGYVMVASVEDLEEKVQPFLKIWPSQAKLFPETRKEVFREVVDDLMGYD
What is the function of this protein?
Involved in protein N-glycosylation.  Essential for the second step of the dolichol-linked oligosaccharide pathway (By similarity).
What are the official names of this protein?
UDP-N-acetylglucosamine transferase subunit ALG13, Asparagine-linked glycosylation protein 13.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: SRY_ORCOR
Sequence: MFRTVNGEDYSPAVQQRNILDFGKSHSRLWTDNGSANDRCETGGNCRESGQDRVKRPMNAFIVWSRDQRRKVALENPQMQNSEISKRLGYDWKMLTEAEKQPFFEEAQRLRAMHRDKYPGYKYRPRRKAKEATEIASRRLFSTVQPNAHRGDVVPLPIQGRLRQGHTFTNGKPVKPLTAHEHKQLTPATGASQQLDKPAPQ
What is the function of this protein?
Transcriptional regulator that controls a genetic switch in male development.  It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells.  Involved in different aspects of gene regulation including promoter activation or repression.  Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.  SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending.  Also involved in pre-mRNA splicing (By similarity).  In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity).
What are the official names of this protein?
Sex-determining region Y protein, Testis-determining factor.
What is the protein family that this protein belongs to?
Belongs to the SRY family.
What are the subcellular locations of this protein?
Nucleus speckle. Cytoplasm. Nucleus.
Protein: SYGA_LEPCP
Sequence: MLTFQHIILRLQDYWDRQGCALLQPYDMEVGAGTSHTATFLRALGPEPWKAAYVQPSRRPKDGRYGNNPNRLQHYYQYQVVLKPAPANILDLYLGSLEALGFDLKKNDIRFVEDDWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGIDCKPITGEITYGLERLAMYLQGVENVYDLQYAPGLTYGDVFHQNEVEQSTYNFEHSNVEFLLSAFGAHEGNAQELMAQQLALPAYEQVLKAAHTFNLLDARGAISVTERAAYIGRIRNLARAVAAAYLDSRARLGFPMAPRAWADEIGAKLAAEAEKAALKNEAKKAA
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_POLNS
Sequence: MQLNPSEISELIKSRISELGVDSQVRNEGTVISVTDGICRVHGLSGVMQGEMLEFPNNTIGLALNLERDSVGAVVLGEYTHIKEGDPVKCTGRILEVPVGPELLGRVVSVLGQPIDGKGPINTKLTDFIEKVAPGVIARQSVSQPVQTGLKAIDAMVPIGRGQRELIIGDRQTGKTAVAVDAIINQKGKGVYCVYVAIGQKASTIANVVRKLTENGAIDYTIVVAASASESAAMQYLSAYAGCTMGEYFRDRGEDALIVYDDLTKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVNAEYVEKFTNGAVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLFNAGVRPAINAGISVSRVGGTAQTKVIKKLSGGIRTDLAQYRELAAFAQFASDLDEATRKQLERGRRVTELCKQAQYKPLQVWEMAASLYAVNNGFFDDLEVKNVLAFEKGLQDHLKSKYADLVARIEATKDLSKDDEAALRAAVEDYKRSASF
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ENO_CLOBB
Sequence: MNDYLEIIDVVARQILDSRCFPTVEVEVYLEDGTIGRAAVPSGASTGMYEAVELRDGDKDKYLGKGVLTAVQNVNDTIAEALIGCNVFDQPYIDKMLIELDGTDNKGKLGANAILGVSLAVANAAANALGLSLYKYVGGVNAKVLPVPMMNIINGGSHADNSVDLQEFMIMPVGATSFTEALRMCAEVYHTLKNTLKDKGYATGLGDEGGFAPNLKSNAEAIDVIIEAITKAGYKAGEDMFIAIDAASSEYYKDGKYVLENEGKTLTSAEMVDFFEDWVNKYPIISIEDGMAEEDWDGWKLLNERLGKKVQLVGDDLFVTNTERLEKGIEIGAANSILIKLNQIGTLTETLNAIEMANRAGYTAVISHRSGETEDTTISDLVVAVNAGQIKTGAPARSERVAKYNQLLRIEEELEDVAEYRGKKAFFNIKK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: MZM1_PICGU
Sequence: MSSRALSAYRAALRATRISFQQDNDVLLAARKQIRDGFEASRNSDNAEEEIVKMNEISKFLVSNIVQGEKQGDGKYFLKFHDQTELGDNETIKQNHKANMGSLAGAKAKCR
What is the function of this protein?
Assembly factor required for Rieske Fe-S protein RIP1 incorporation into the cytochrome b-c1 (CIII) complex.  Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane.  Modulates the mitochondrial matrix zinc pool (By similarity).
What are the official names of this protein?
Mitochondrial zinc maintenance protein 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family. MZM1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: F167A_BOVIN
Sequence: MSVPQIQVEEVAGGEEGPAGTTPPPDDHLRSLKALTEKLRLETRRPSYLEWQARLEEQTWPFPRPAAEPRGSGEEEPSLLRTRALRPHPPPNGRANQDDGHPPTGKLEGFESIDEAIAWLRKELMEMRLQDQQLARQLMRLRSDIHKLKIEQTCDLHRRMLNDATYELEERDELSDLFCDAPLASSFSLSAPLKLIGVTKMNINSRRFSLC
What are the official names of this protein?
Protein FAM167A.
What is the protein family that this protein belongs to?
Belongs to the FAM167 (SEC) family.
Protein: RL3_SALDC
Sequence: MIGLVGKKVGMTRIFTEDGVSIPVTVIEVEANRVTQVKDLANDGYRAVQVTTGAKKANRVTKPEAGHFAKAGVEAGRGLWEFRLAEGEEYTVGQSISVELFADVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKKMAGQMGNERVTVQSLDVVRVDAERNLLLVKGGVPGATGCDLIVKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: PLA2_WALAE
Sequence: NLYQFKNMVQCVGTQLCVAYVKYGCYCGPG
What is the function of this protein?
Relatively highly potent phospholipase A2 that displays potent antimicrobial and hemolytic activities.  It does not show cytotoxic effects on the three human cell lines tested.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.  It shows similar potencies on both Gram-negative and Gram-positive bacteria: B. cereus (MIC>9 ug/ml), B. subtilis (MIC>12 ug/ml), E. faecalis (MIC>7 ug/ml), S. epidermidis (MIC>12 ug/ml), S. aureux (MIC>5 ug/ml), E. coli (MIC>7 ug/ml), K. pneumonia (MIC>8 ug/ml), P. aeruginosa (MIC>10 ug/ml), and S. enteric (MIC>9 ug/ml).  It also shows antifungal activities: A. niger (MIC>15 ug/ml), B. cinerea (MIC>12 ug/ml), F. solani (MIC>15 ug/ml), and P. digitatum (MIC>10 ug/ml).
What are the official names of this protein?
Non-toxic phospholiapse A2, WaPLA2, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: KPRS_BACAN
Sequence: MSTQYLNSNLKVFSLNSNKELAEQIAKHIGVGLGKCSVDRFSDGEVQINIEESIRGCDVFIIQSTSFPVNEHIMELLIMIDALKRASAKTINIVIPYYGYARQDRKARSREPITSKLVANLLETAGATRVITLDLHAPQIQGFFDIPIDHLMGVPILSDYFETKGLKDIVIVSPDHGGVTRARKMADRLKAPIAIIDKRRPRPNVSEVMNIIGNIEGKTAILIDDIIDTAGTITLAANALVENGASEVYACCTHPVLSGPAIERIQNSNIKELVVTNSIVLPEEKKIDKVHELSVAPLIGEAIIRVYEEESVSVLFN
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase, RPPK, 5-phospho-D-ribosyl alpha-1-diphosphate synthase, Phosphoribosyl diphosphate synthase, Phosphoribosyl pyrophosphate synthase, P-Rib-PP synthase, PRPP synthase, PRPPase.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.