PharMolix/UniProtQA huggingface dataset:
Protein: HUTI_GEOKA
Sequence: MRPLFVRRARQLVTLAGSSAAPLVKEKMSDLGIIENGSVWIENGTIVAVGPDDELVRRFADRLAEAEVIDAKGKTVTPGLIDPHTHLVYAGSREHEWTMRLHGATYMEIMNAGGGIHATTKATREASEEALYEESKRRLDQFLLHGVTTVEAKSGYGLSLEHEIKQLEIAKRLHDTHPVDIVSTFLGAHAVPPEWKHDPDEYVRLVIDEMIPEVSRRGLAEFNDVFCERGVFTPDQARRMLEAGKASGLTPKIHADEIEPYGGAELAAEVGAISADHLLRASDEGIRRMADGGVIGVLLPGTAFFLMTKAADARRLIDAGVPVALATDCNPGSSPTVSLPLVMSLACLHMGMTPAEAMAAATINAAHAIGRAHLVGSLEPGKKADLVIFNVPNYMQIMYYYGVNHAETVIKGGKVVVNDGKVYI
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CA167_HUMAN
Sequence: MTRMSCPWGSYQWEPGACPAAPRGIGGGDMAGGIPDVRGLQEAALGAGRSQEEARLVEEAQTPVMLPQDSGQRVEEVPGDLMAKRMSLILHVQKLPWDHVPCLRRTRQNLYQDVGGHAHGSGLGGAKRGAARSALRRPLPPATCRPAGIVSGPSPRLDSNPTGAHLIKQTRPLTVEWTKDTPVPEPMELRSDASHKENVSPKPAALPKPGKRLKQRRFRRSLGIGLSGRHDQWVPGCQVERGGPAATPSPGAVLDQEPCRVQTNLASPGPRLGLALKDTTGQLVNSSFWQQSNLQSLARRRQGKAREFAIQQSNLSINETSSPHLCPEPGGSSGPHKLPWGPLLSQEPLARPSSCLRQSGLPAPGTPSGDFRPTEAFAPLDGHTQPGLRSWGGLGSWRSRLVGEPLTLEDLAVPSQNQTQAPSRAAVHQLLASVHCLAQEAARLRCQAPQEPPAWGVSPKQKGEEGAPRERVHREEERTAFHLSDTVPASSASKNKAQNITAPESEAICWQLLSRCFRSWRHLVKRQREPAAAAVALGRWQLLRKCLQALWLREAQLEAAWGQYTKVLLVRSFREVSGLQVGPGGRVKQCPGSLREEEIAQRLLSHPRQRTDSRHERVQILQALQLAVFFLWCQQKKRARQERETLRKATRATQRTGSFPQAWHSTAAGVAWVAPLSPQHQRAWLCRCFGAWQQFVQRGSRYRDHLADRRTGTLRKCLEQWVRMKQLRESDGAKVTQLSLCRQKAGREAVYTAGPGACGLGAVGQAQGQQEQGRGSLQDACWTLALCWALLLWKMRLFQRQWANSFFQGLQQRMLQRSLRWWHLRALGPDATSSCTKTPSALEPLSSSTLQDSLEKVPRAPTLPDTLQGSLLWAAGQRQQGQCLLLWQARAQQFQGTARWYQHTRQRRIFLSWSRWATAQWAWRELASHRAWDRTCRAVLGLWRQRLLQSRLVEWWAQERGWRLARDALCHWHSCWQGQQFLHEKCQTWVQVHLQGLQKVVFRSWQQAAAHQRCTVTRPEQLLLQSYFQAWCEVVRDTGVLRAQHQAFQDGLRRRALGAVFATWREAQEVAAGAQEQRVAQASLARWRSCGQQGQEDGQQKKARAPQAFPAWPVAPGMHHEAQQQAGESAGAQAAQCWTWCWALWVHESCRGQVSRAHASWKPRAWVLEASVQSAVRGGVQRAILTQLRPAELRRFLRTVQLRVRLGLPGAGKTRSCWTQATELVPPAPSLQCSLGGRRKPRGTAWAQRCREHSLCPAFQLWPQWPGQSSWVPGLPLWTRDQGPRAHSSPEPRACKAQSKAHKRRLRILEKQAQAHGSALLLALKGHDALGHQEEVPAAPVPRGTASRAAGFPAGQVPGSGMAALGGCPRGRAAGADPAQGVAPEMGLADVVAADPATASGSAVTAAGRWAFKKWHQRLAARSPRRGAASSPRPWSKPGPKGPESGQEAARAPRGWGLGAEHGAQLQL
What are the official names of this protein?
Uncharacterized protein C1orf167.
Protein: Y2993_MYCTU
Sequence: MRIGRIASPDGVAFASIDGELGEPSEMTAREIAEHPFGTPTFTGRSWPLADVRLLAPILASKVVCVGKNYADHIAEMGGRPPADPVIFLKPNTAIIGPNTPIRLPANASPVHFEGELAIVIGRACKDVPAAQAVDNILGYTIGNDVSARDQQQSDGQWTRAKGHDTFCPVGPWIVTDLAPFDPADLELRTVVNGDVKQHARTSLMIHDIGAIVEWISAIMTLLPGDLILTGTPAGVGPIEDGDTVSITIEGIGTLTNPVVRKGKP
What are the official names of this protein?
Protein Rv2993c.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the FAH family.
Protein: RFCS_THEKO
Sequence: MSEEVKEVKILEKPWVEKYRPQRLEDIVGQDHIVKRLKHYVKTGSMPHLLFAGPPGVGKCLTGDAKVIANGRLFELGELVEKVSKGRFGPTPVEGLKVLGIDEDGKLREFEVQYVYKDRAERLIKVRTRLGRELKVTPYHPLLVNRKNGEIMWVKAEELRPGDRLAVPRFLPAIAEEDPLAEWLGYFIGDGHADSKNKVITFTNTDPSLRQRFMELTERLFPDAKIRERIHKNRAPDVYVNSRRAWELVSSLGLAGRKADKVYIPEKGWEGIRSFLRAYFDCDAGVDKNAVVLATASREMAEQVTYALAGFGITSKIREKKVRGKTYYHVTISGSENLERFLSEIGFSHREKLERTLKLVKKPNPNLDSLNVNYELISYVRDRLKLNFSDDKRSWSHRKARKISWELMKEIYYRLDELERLKESLSRSILIDWNEMAERRKEIAEKTGIRADRLLEYIKGKRKPSLRNYIKIAKALGIDLEPTINAMRVFARKYSSYAEIGRKLGTWNSSVRIILESNTEKIKELEEIRKIELELIGEILSDEKLKEGVAYLIFLSQNELYWDEITEVKELKGDFVIYDLHVPGYHNFIAGNMPTVVHNTTAALALARELFGENWRHNFLELNASDERGINVIREKVKEFARTKPIGGASFKIIFLDEADALTQDAQQALRRTMEMFSNNVRFILSCNYSSKIIEPIQSRCAIFRFRPLRDEDIAKRIRYIAENEGLELTEEGLQAILYVAEGDLRRAINVLQAAAALDTKITDENVFLVASRARPEDVREMMTLALEGNFLKAREKLRDILLRQGLSGEDVLIQMHKEVFNLPIPEDKKVALADKIGEYNFRLVEGANEMIQLEALLAQFTIMGK
What is the function of this protein?
Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.
What are the official names of this protein?
Replication factor C small subunit, RFC small subunit, Clamp loader small subunit.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family. RfcS subfamily.
Protein: RRP36_YEAS7
Sequence: MSYYFKNLKPDLNSDVEEDDGNLLESIMANKSKREIDEQESSDDELKTLSFGSLKKAETVIDEEDFKDTKPVHKKPITTTYREESFDEDEDSEDQSDEDAGFFEEDSEDETHHGQKVPKKKSKHAPVEQSSKKRVPRVRNIPGLEIPRNKRSNLYRDIRFDKSTGKALDSSIIRKRYQFLDEYREKEIDELQKLLQDRKFLSKIDQGEREEMEQRLKSMKSRLQSMKNKDLEREILKEYENDMNKNNNTRYHLKKSEKRKVVQKWKFDHMKTKQREKVMERKRKKRLGKEFKQFEFHNRR
What is the function of this protein?
Component of the 90S pre-ribosome involved in the maturation of rRNAs.  Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity).
What are the official names of this protein?
rRNA biogenesis protein RRP36, Ribosomal RNA-processing protein 36.
What is the protein family that this protein belongs to?
Belongs to the RRP36 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: Y503_MYCPN
Sequence: MNGVAQDKVHGLEQTTQWNQQASQKNLTNNPAPKAVTGFKLDKGRAYRKLNEAWPVYEPLDSTKDGKGKDKDGWTTSGASEPKGDAPLVSSTESQMAAVTDSQQSGHNSGLVSLAQRSTTVAVQKSDSSGSQGQGTTDNKFQKYLNTAQALHQMGVIVPSLETWPGKPSTGIATRAGGGVSVQAATRQSSSTNEDLPNVITQLYHTSTSQLAYLNGQIVVMGSNAVPSLWYWVVDERTTSGRATWWAHTELNWGTDKQKQFVENQLGFKDDSNSSLTNFKSQGLTQPAYLIAGLDVVQDHLVFAAFKAGAVGYDMTTDSNASTKDQALAWSTTAGLDSAGGYNKLVENTGGLNGPINELVYPARHLCLCDPGEWDERGESE
What are the official names of this protein?
Putative MgpC-like protein MPN_503.
What is the protein family that this protein belongs to?
Belongs to the MgpC family.
Protein: NU3C_GOSHI
Sequence: MFLLYEYDIFWAFLIISSAIPILAFLISGVLAPIRKGPEKLSSYESGIEPMGDAWLQFRIRYYMFALVFVVFDVETVFLYPWAMSFDVLGVPVFIEAFIFVLILIVGSVYAWRKGALEWS
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic, NAD(P)H dehydrogenase subunit 3, NADH-plastoquinone oxidoreductase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: KATG2_SHESA
Sequence: MKKSTIPSMSALTLAMSLAFGGAAIAQEQVTGNQFWWPEQLNLSPLRQNAVESNPYGSDYHYAEAFKSLDLDAVKKDIKALMTESQDWWPSDYGHYGPFFIRMAWHSAGVYRIFDGRGGAAGGQQRFEPLNSWPDNVNLDKARRLLWPIKQKYGSKISWGDLMVLTGNVALESMGFKTFGFAGGRVDDWEAEQVNWGSEKAWLDSKRRNEKGELAKPMGATQMGLIYVNPEGPNGVPDPLASAKEIRDTFGRMAMNDEETVALIAGGHTFGKAHGAHDPSKCVGADPAASGVEAQGLGWKNKCGKGHSEDTVTSGLEGAWSVNPTAWTMQYLENLYGFDWVQTKSPAGHIQWIPKDGKGANLVPDAHDKSKRHAPIMFTSDIALKEDPSYREITTRFLKNPKEFELAFAKAWFKLTHRDMGPKARYLGADVPAEMLIWQDPIPALDHPVIDNADIKALGNKILASGLTVPELVRTAWASASSFRGTDMRGGANGARIRLEPMMNWQANNPKELAKVLAKLEKVQKDVNSSLKGGKKVSLADVIVLGGSVAVEKAAKEAGVTVSVPFTPGRMDATQAQTDVSSFAVLEPTADGFRNYYSKDSSHSPAEMLIERANMLNLTVPEMTVLVGGLRALDANSAGVKHGVFTDKPGTLSNDFFVNLLDMSTKWSKSEKQEGIYEGQDRKSGKLKWTATPVDLVFGSHSELRAVSEVYGAQDGQDRFVQDFIKAWNKVMNADRFDI
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase 2, CP 2, Peroxidase/catalase 2.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: MPPE1_HUMAN
Sequence: MAMIELGFGRQNFHPLKRKSSLLLKLIAVVFAVLLFCEFLIYYLAIFQCNWPEVKTTASDGEQTTREPVLKAMFLADTHLLGEFLGHWLDKLRREWQMERAFQTALWLLQPEVVFILGDIFDEGKWSTPEAWADDVERFQKMFRHPSHVQLKVVAGNHDIGFHYEMNTYKVERFEKVFSSERLFSWKGINFVMVNSVALNGDGCGICSETEAELIEVSHRLNCSREARGSSRCGPGPLLPTSAPVLLQHYPLYRRSDANCSGEDAAPAEERDIPFKENYDVLSREASQKLLWWLQPRLVLSGHTHSACEVHHGGRVPELSVPSFSWRNRNNPSFIMGSITPTDYTLSKCYLPREDVVLIIYCGVVGFLVVLTLTHFGLLASPFLSGLNLLGKRKTR
What is the function of this protein?
Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi.  Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins.
What are the official names of this protein?
Metallophosphoesterase 1, Post-GPI attachment to proteins factor 5.
What is the protein family that this protein belongs to?
Belongs to the metallophosphoesterase superfamily. MPPE1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein. Note=Also localizes to endoplasmic reticulum exit site.
Protein: LDH_TREDE
Sequence: MDEKKRKVTVVGAGAVGSTFAYALAQSGYADEIAITDMNKNFAEGQALDLVQGLPFLPQVDIHAGDKTDYADSDIVVVTAGAKQQSGETRIDLLKRNASIITGIAKDIAESGCSGVMLIVSNPVDILTRAALKASGWERGRVIGSGTVLDTARFRYTLSKECGVDARNIHGYILGEHGDSEFAAWSMTSVAGRRIDEYCSGGVCSSGPHFDKAKILEEVRNSAYHIIDYKGSTYFAVGLALTRIAGAILRNEHSILSVSMTLDGEFGLKDVCLSVPCIVGRSGAERVIESDLPADEQAALEASAKRLKEAFTEMN
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URED_DECAR
Sequence: MTSRLPISQPEHSPSWHAELHLGFARAGERTVLRENRHRGPLRVQKALYPEGEAVCQTIVLHPPSGIAGGDHLAISAEVGEGSHAQLTTPGAGKWYRSGGAEASQRVAFTVGEGATLEWLPQETIVFDGARARMETQVDLAADSRYIGWDILCLGRVAAGERFEKGRFDLFLQVNRDQRPIWIERGGFDGSDPMLISPAGWAGATVCGTLLCAFPEWPMQASALLEACRKIVPADGAQHGLSALPGVLIARYLGNSSEAARLWFAELWTILRPACCGRPAVIPRIWNT
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA1_STAAE
Sequence: MGFLSKILDGNNKEIKQLGKLADKVIALEEKTAILTDEEIRNKTKQFQTELADIDNVKKQNDYLDKILPEAYALVREGSKRVFNMTPYKVQIMGGIAIHKGDIAEMRTGEGKTLTATMPTYLNALAGRGVHVITVNEYLSSVQSEEMAELYNFLGLTVGLNLNSKTTEEKREAYAQDITYSTNNELGFDYLRDNMVNYSEDRVMRPLHFAIIDEVDSILIDEARTPLIISGEAEKSTSLYTQANVFAKMLKQDEDYKYDEKTKAVHLTEQGADKAERMFKVENLYDVQNVDVISHINTALRAHVTLQRDVDYMVVDGEVLIVDQFTGRTMPGRRFSEGLHQAIEAKEGVQIQNESKTMASITFQNYFRMYNKLAGMTGTAKTEEEEFRNIYNMTVTQIPTNKPVQRNDKSDLIYISQKGKFDAVVEDVVEKHKAGQPVLLGTVAVETSEYISNLLKKRGIRHDVLNAKNHEREAEIVAGAGQKGAVTIATNMAGRGTDIKLGEGVEELGGLAVIGTERHESRRIDDQLRGRSGRQGDKGDSRFYLSLQDELMIRFGSERLQKMMSRLGLDDSTPIESKMVSRAVESAQKRVEGNNFDARKRILEYDEVLRKQREIIYNERNSIIDEEDSSQVVDAMLRSTLQRSINYYINTADDEPEYQPFIDYINDIFLQEGDITEDDIKGKDAEDIFEVVWAKIEAAYQSQKDILEEQMNEFERMILLRSIDSHWTDHIDTMDQLRQGIHLRSYAQQNPLRDYQNEGHELFDIMMQNIEEDTCKFILKSVVQVEDNIEREKTTEFGEAKHVSAEDGKEKVKPKPIVKGDQVGRNDDCPCGSGKKFKNCHGK
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 1.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: HYPA_THERP
Sequence: MHELSVALSLIDALTESLGTHPDVRIEVIHLKIGPLSGVIEPALRSAFEIAAVGTIAEGAILAIQVPPIVLRCEECGQETNLSGADVMDNRDGLGSWISWLPPACPACGAAALTVVGGRELELVAAEVRRG
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: TAF10_YEAST
Sequence: MDFEEDYDAEFDDNQEGQLETPFPSVAGADDGDNDNDDSVAENMKKKQKREAVVDDGSENAFGIPEFTRKDKTLEEILEMMDSTPPIIPDAVIDYYLTKNGFNVADVRVKRLLALATQKFVSDIAKDAYEYSRIRSSVAVSNANNSQARARQLLQGQQQPGVQQISQQQHQQNEKTTASKVVLTVNDLSSAVAEYGLNIGRPDFYR
What is the function of this protein?
Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK.  Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation.  TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription.  SAGA is involved in RNA polymerase II-dependent transcriptional regulation of approximately 10% of yeast genes.  At the promoters, SAGA is required for recruitment of the basal transcription machinery.  It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction (SPT3, SPT8 and SPT20) and promoter selectivity, interaction with transcription activators (GCN5, ADA2, ADA3 and TRA1), and chromatin modification through histone acetylation (GCN5) and deubiquitination (UBP8).  SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac).  SAGA interacts with DNA via upstream activating sequences (UASs).  SLIK is proposed to have partly overlapping functions with SAGA.  It preferentially acetylates methylated histone H3, at least after activation at the GAL1-10 locus.
What are the official names of this protein?
Transcription initiation factor TFIID subunit 10, TAFII-23, TAFII23, TAFII-25, TAFII25, TBP-associated factor 10, TBP-associated factor 25 kDa, p25.
What is the protein family that this protein belongs to?
Belongs to the TAF10 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PAAC_ECOLI
Sequence: MNQLTAYTLRLGDNCLVLSQRLGEWCGHAPELEIDLALANIGLDLLGQARNFLSYAAELAGEGDEDTLAFTRDERQFSNLLLVEQPNGNFADTIARQYFIDAWHVALFTRLMESRDPQLAAISAKAIKEARYHLRFSRGWLERLGNGTDVSGQKMQQAINKLWRFTAELFDADEIDIALSEEGIAVDPRTLRAAWEAEVFAGINEATLNVPQEQAYRTGGKKGLHTEHLGPMLAEMQYLQRVLPGQQW
What is the function of this protein?
Component of 1,2-phenylacetyl-CoA epoxidase multicomponent enzyme system which catalyzes the reduction of phenylacetyl-CoA (PA-CoA) to form 1,2-epoxyphenylacetyl-CoA.  The subunit C may be essential for structural integrity of the alpha subunit.
What are the official names of this protein?
1,2-phenylacetyl-CoA epoxidase, subunit C, 1,2-phenylacetyl-CoA epoxidase, structural subunit beta, 1,2-phenylacetyl-CoA monooxygenase, subunit C.
Protein: BPHC_PSES1
Sequence: MSIERLGYLGFAVKDVPAWDHFLTKSVGLMAAGSAGDAALYRADQRAWRIAVQPGELDDLAYAGLEVDDAAALERMADKLRQAGVAFTRGDEALMQQRKVMGLLCLQDPFGLPLEIYYGPAEIFHEPFLPSAPVSGFVTGDQGIGHFVRCVPDTAKAMAFYTEVLGFVLSDIIDIQMGPETSVPAHFLHCNGRHHTIALAAFPIPKRIHHFMLQANTIDDVGYAFDRLDAAGRITSLLGRHTNDQTLSFYADTPSPMIEVEFGWGPRTVDSSWTVARHSRTAMWGHKSVRGQR
What are the official names of this protein?
Biphenyl-2,3-diol 1,2-dioxygenase, 2,3-dihydroxybiphenyl dioxygenase, DHBD, 23OHBP oxygenase.
What is the protein family that this protein belongs to?
Belongs to the extradiol ring-cleavage dioxygenase family.
Protein: CYAY_NEIG2
Sequence: MMTESEFIRASEALFEHIEDQIDENGWDFDCRFAGNVLTIEAGDGTQIIVNRHTPNQELWIAAKSGGYHFAEQNGKWLATRDSRDFYDVLNEALSAASGEAVEIAEL
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: RHAS_ECOL5
Sequence: MTVLHSVDFFPSGNASVAIEPRLPQADFPEHHHDFHEIVIVEHGTGIHVFNGQPYTITGGTVCFVRDHDRHLYEHTDNLCLTNVLYRSPDRFQFLAGLNQLLPQEQDGQYPSHWRVNHSVLQQVRQLVAQMEQQEGENDLPSTASREILFMQLLLLLRKSSLQENLENSASRLNLLLAWLEDHFADEVNWDAVADQFSLSLRTLHRQLKQQTGLTPQRYLNRLRLMKARHLLRHSEASVTDIAYRCGFSDSNHFSTLFRREFNWSPRDIRQGRDGFLQ
What is the function of this protein?
Activates expression of the rhaBAD and rhaT operons.
What are the official names of this protein?
HTH-type transcriptional activator RhaS, L-rhamnose operon regulatory protein RhaS.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LUM_RAT
Sequence: MNVCTFTLVLALVGSVSGQYYDYDAPLFMYGELSPNCAPECNCPHSYPTAMYCDDLKLKSVPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGKVFSKLKQLKKLHINYNNLTESVGPLPKSLQDLQLANNKISKLGSFDGLVNLTFIYLQHNQLKEEAVSASLKGLKSLEYLDLSFNQMSKLPAGLPTSLLTLYLDNNKITNIPDEYFNRFTGLQYLRLSHNELADSGVPGNSFNISSLLELDLSYNKLKSIPTVNENLENYYLEVNKLEKFDVKSFCKILGPLSYSKIKHLRLDGNPLTQSSLPPDMYECLRVANEITVN
What are the official names of this protein?
Lumican, Keratan sulfate proteoglycan lumican, KSPG lumican.
What is the protein family that this protein belongs to?
Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: CSTFT_HUMAN
Sequence: MSSLAVRDPAMDRSLRSVFVGNIPYEATEEQLKDIFSEVGSVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRNLNGREFSGRALRVDNAASEKNKEELKSLGPAAPIIDSPYGDPIDPEDAPESITRAVASLPPEQMFELMKQMKLCVQNSHQEARNMLLQNPQLAYALLQAQVVMRIMDPEIALKILHRKIHVTPLIPGKSQSVSVSGPGPGPGPGLCPGPNVLLNQQNPPAPQPQHLARRPVKDIPPLMQTPIQGGIPAPGPIPAAVPGAGPGSLTPGGAMQPQLGMPGVGPVPLERGQVQMSDPRAPIPRGPVTPGGLPPRGLLGDAPNDPRGGTLLSVTGEVEPRGYLGPPHQGPPMHHASGHDTRGPSSHEMRGGPLGDPRLLIGEPRGPMIDQRGLPMDGRGGRDSRAMETRAMETEVLETRVMERRGMETCAMETRGMEARGMDARGLEMRGPVPSSRGPMTGGIQGPGPINIGAGGPPQGPRQVPGISGVGNPGAGMQGTGIQGTGMQGAGIQGGGMQGAGIQGVSIQGGGIQGGGIQGASKQGGSQPSSFSPGQSQVTPQDQEKAALIMQVLQLTADQIAMLPPEQRQSILILKEQIQKSTGAS
What is the function of this protein?
May play a significant role in AAUAAA-independent mRNA polyadenylation in germ cells.  Directly involved in the binding to pre-mRNAs (By similarity).
What are the official names of this protein?
Cleavage stimulation factor subunit 2 tau variant, CF-1 64 kDa subunit tau variant, Cleavage stimulation factor 64 kDa subunit tau variant, CSTF 64 kDa subunit tau variant, TauCstF-64.
Protein: RECR_FRATW
Sequence: MTSKIFSPKISAVIESLRKLPTIGKKSSQRLALYLLDKSPETAIAIANSLLDATANIKKCVYCQALTEDDVCNICSNTNRDDTKLCIIESMLDMIAIEEAGIYRGKYFVLNGRISPLDGIGPSELKLDILQQIIADRKIDEVILAISPTVEGETTAHFISQMIAKDIKISRIGFGVPFGGELEYLDQQTLLHAFNARTNI
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: DAPB_BURL3
Sequence: MKIAIAGASGRMGRMLIEAVLNDSDAQLVGALDRADSPFLGQDAGTFLGKETGVKLTADLDAVFAQADTLIDFTRPEGTMAHIEAALRHDVKLVIGTTGFTAEQKAELQAAAGKIGIVFAANMSVGVNVTLKLLEFAAKHFSHGYDIEIIEAHHRHKVDAPSGTALMMGEAVAGALGRSLDDCAVYGRHGVTGERDPSSIGFAAVRGGDIVGDHTVLFAGIGERIEITHKSSSRVSYAQGALRAVHFLSARGAGLFDMQDVLGLR
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPO6_PICTO
Sequence: MIFMILTKFEKARIIGARALQIAMGAPVIIDISPDIIDPIDIAMIEFENNVIPITIKRNQ
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo6, DNA-directed RNA polymerase subunit K.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS1_GLOC7
Sequence: MITIALPKGALLSDSIALFKQIGLDFTAFLDSSNRQLQISDPTNTAKALLVRAQDVPVYVEYGQAQLGIVGYDVLLEKTPKVANLADLKFGACRMSVAVPAKSPYRSSIELPPNGRVASKFVHCAEDYFRRLDIPVEIIPLYGSVELGPITGMSDAIVDLVSTGRTLRENGLVEIDVLFESTARLIAHPLSYRLNLDHLDQWVNKLRQINLKPVA
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCBP1_DROAN
Sequence: MSRRRAHDTEDEGYDHRRNKRRRVSENQEIEDRLESLILRVGERSTSSVESNLEGLVSVLEADLGTFRLKILRILSDCAVRMPEKCTVYTTLVGLLNAKNYKFGGEFVDHMVKTFKESLKLCRWDAARYSLRFLADLVNCHVISATSLLQLLDTMIDVSNEDTVPQVRRDWFVFAVLSTLPWVGRDLYEKKESALESLLLRIEVYLNKRSKKHHNALRVWSSDAPHPQEEYLDCLWAQIRKLRQDNWAEKHIPRPYLVFDSILCEALQHNLPQIVPPSHHDAFEYPMPWVVYRMFDYTDCPDGPNLPGAHSIERFLIEEHLHHIIETYHHERKDCAAQLLSFPFKHKIPLEYCIVEVIFAELFHMPTPRYLDICYGSILIELCKLQPATLPQVLAQATEILFMRIDSMNTSCFDRFVNWFSYHLSNFKFTWSWDEWDSCLLLDAEHPRPKFIQEVLQKCLRLSYHQRITEMMPTTYLKLIPPTPSPNYKYANEEAANLPGTTVAHQLVVAIRQKCLPEEVVNILKEIPSSGYSGEEMSDGSFNALKIDVFVQTLLNLGSKSFSHSFAAISKFHSVFRALAETEEAQICILHNIFELWSTHQQMMVVLIDKLLKLQIVDCSAVATWIFSKEMTGEFTKMYLWEILHLTIKKMNKHVIKLNTELSEAKDKLSKADSSSSDSDDDTPHKRKKPITHADKPSEEVVERMEEKLEAANVNQKRLFLIVFQRFIMILSEHLLRSDTDGRDPDTDWYRWTIGRLQQVFLMHHEQVQKYSSTLETLLFTSDLDTHILEVFQQFVALRA
What is the function of this protein?
Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi).  The CBC complex is involved in miRNA-mediated RNA interference via its interaction with Ars2 and is required for primary microRNAs (miRNAs) processing.  Also involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production.  In the CBC complex, Cbp80 does not bind directly capped RNAs (m7GpppG-capped RNA) but is required to stabilize the movement of the N-terminal loop of Cbp20 and lock the CBC into a high affinity cap-binding state with the cap structure (By similarity).
What are the official names of this protein?
Nuclear cap-binding protein subunit 1, 80 kDa nuclear cap-binding protein, CBP80, NCBP 80 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the NCBP1 family.
What are the subcellular locations of this protein?
Nucleus.