PharMolix/UniProtQA huggingface dataset:
Protein: TSAD_RUTMC
Sequence: MTSSVSTMHNNQDQQTTQLDFITLGIESSCDETGIGLYHSELGLIGHELFSSVKIHAEYGGVVPELASRDHIQRVLPLIKAVLADVKFTLQDLSGIAYTAGPGLAGALLVGCAVAKSLAWSLDIPSLAVHHMEGHLLTPLLEESQPEFPFVALLVSGGHTMLIDVKAIGQYKILGESLDDAVGEAFDKTAKILGLGYPGGPALAMLAEQGNYGAFKFPCPMVGRPGLDFSFSGLKTFVRNTFAKYPSKKEDIAKAFEVATTQTLMIKCRRALEQTKYATLVVAGGVSANLSLRKKLNQMGQKLDVNVFYPRQEFCTDNGAMIALVGYFRLSHGQHDTHHEINIKPRWSLEELSQIE
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OMPG_ECOLI
Sequence: MKKLLPCTALVMCAGMACAQAEERNDWHFNIGAMYEIENVEGYGEDMDGLAEPSVYFNAANGPWRIALAYYQEGPVDYSAGKRGTWFDRPELEVHYQFLENDDFSFGLTGGFRNYGYHYVDEPGKDTANMQRWKIAPDWDVKLTDDLRFNGWLSMYKFANDLNTTGYADTRVETETGLQYTFNETVALRVNYYLERGFNMDDSRNNGEFSTQEIRAYLPLTLGNHSVTPYTRIGLDRWSNWDWQDDIEREGHDFNRVGLFYGYDFQNGLSVSLEYAFEWQDHDEGDSDKFHYAGVGVNYSF
What is the function of this protein?
May act as a regulator of the RCS-phosphorelay signal transduction pathway.
What are the official names of this protein?
Outer membrane porin G, Outer membrane protein G.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: ERA_COXBU
Sequence: MKPTYCGYAAIIGRPNVGKSTLLNQLLEQKISITSRKPQTTRYQILGVKTFKDIQVIYVDTPGLHAGTERTINRYMNRTARGALRDVDAIVFVIEPHWESQDAWVLDNLKEIETPVFLVINKVDKIKNRAELLPLIEKVSSLYAFQKITPLSAKTGDQVGTLEQAVHQLMPESPFYFPPEQVTDRSDQFMASEIIREKLMRLLGQEIPYSLAVTLIEFRKEEKIIRISAVIWVEKKSQKGIVIGKGGERLKRVGTNARLDMEKWFGKRVFLQLWVKVKSGWADNERLLRELGFEE
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: TRPF_HALSA
Sequence: MTRVKVCGLTTERDHAAAVAAGADAVGIIADVPVETPREVSVETATALRAATPPFVTSVLVTMPATPEHAVDLVRTVAPDAVQLHGDLPVGDAAYVAANTPCPVIKAVTAGDQSAARYADVVDALLVDSPPTDDAGAGGGTGRTHDWAATRAFADRVDTPVVLAGGLTPANVADAVDTVDPFAVDVASGVEARPGEKDHAAVSAFVARATATPDPTLT
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: RL34_PECAS
Sequence: MKRTFQPSVLKRNRSHGFRARMATKNGRQVLARRRAKGRTRLSVSK
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: ARNB_PSEA7
Sequence: MSLDFLPFSRPSIGEDEIAAVEQVLRSGWITTGPQNQELEQRFAERLGCRHAVALSSATGALHVTLLALGIGPGDEVITPSLTWVSTANVITLLGATPVFVDVDRDTLMCSAQAVEAAIGPRTRAIVPVHYAGSTLDLEGLRTVAGRHGIALVEDAAHAVGSEYRGRPVGARGTAIFSFHAIKNLTCAEGAMFVSDDSALAERVRRLKFHGLGVDAYDRLSHGRKPQAEVIEPGFKYNLADLNAALALVQLKRLDALNARRQALAERYLERLAGLPLAPLGLPAHAQRHAWHLFILRIDAEACGLGRDAFMEALKARGIGSGIHFIASHLHHYYRQRQPRLSLPNSEWNSARLCSIPLFPDMRDDDIERVARAIEDILEKRR
What is the function of this protein?
Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase, UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase, UDP-Ara4O aminotransferase, UDP-4-amino-4-deoxy-L-arabinose aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.
Protein: PRIA_RHORU
Sequence: MAGLPALPPGSRELFPEDAHAEPVVAVLLPLPLAGAYDYKVPAGMARPAVGTLVRVPLGRREEIGVVWGAGAGETPPERLKPLIGFPECPPLPAPLRAFIDWVAAYTVQPPGAVLRMALSVPAALEAPPPALGWRRPSAGQRAAGQRAEGQGPLPGGARLSPGRQRVLAVLDDHPGLPFAGADLAREAAVGPAVVAAMAKAGLLEAVTRSNEWSPQAPDADRPGPLLSADQQAAADGLRTALDQGFSGLLLEGVTGSGKTEVYFEAIAETLRRGRQALVLLPEIALAAQWPRRFADRFGAAPVQWHSQMGAAARRRAWRAVALGRAPVVVGARSALFLPYPDLGLIIVDEEHDSAFKQEEGVPYNARDMAVVRARLGGFPAVLASATPSLETIENARQGRYRHLVLPRRHGGAEMPEITLLDLRRAPPQKWLPTDFAGPGGSEGLAAPGGANDEAEEQKAPPPSPTASPSPTASPSPMARPARLGWLSPPLITAVEETLAAGEQVLLFLNRRGYAPLTLCRSCGHRLKCPRCTAWLVEHRRDGRLRCHHCGYQQPIPETCPACGVADSLAPCGPGVERLAEEAAHRFPKARMDVAASDTVTGPKEAAALATRIANHDIDLIIGTQIMAKGHHFPLITLVGVVDGDLGLTGGDLRASERTHQLLHQVAGRAGRAERPGRVLIQTVDPGHPVMEALASGDPALFLEVEAAERQALAMPPFGRLVALVISGEDSARVQAVAAALGRAAPMGPGLDVLGPVPAPLAMLRGRHRHRLLLKAARGVKVQPVVRHWLSLVSIPPGVKVQVDVDPISFL
What is the function of this protein?
Involved in the restart of stalled replication forks.  Recognizes and binds the arrested nascent DNA chain at stalled replication forks.  It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
What are the official names of this protein?
Primosomal protein N', ATP-dependent helicase PriA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. PriA subfamily.
Protein: Y2264_ARCFU
Sequence: MRCSVTKFFCSTAKKSQMVERVKDYMYKNDKLFELLDARILEMKEGYAKVEMVVKKEHLNAANVCHGGIIFSLADLAFALASNSHGKLALAIEVSITYMKAAYEGEKLVAEAKEVNLGNKTATYLMEVKNSANKLIALAKGTVYRVNEDFPPTS
What are the official names of this protein?
Putative esterase AF_2264.
What is the protein family that this protein belongs to?
Belongs to the thioesterase PaaI family.
Protein: MNTH_ECO8A
Sequence: MTNYRVESSSGRAARKMRLALMGPAFIAAIGYIDPGNFATNIQAGASFGYQLLWVVVWANLMAMLIQILSAKLGIATGKNLAEQIRDHYPRPVVWFYWVQAEIIAMATDLAEFIGAAIGFKLILGVSLLQGAVLTGIATFLILMLQRRGQKPLEKVIGGLLLFVAAAYIVELIFSQPNLAQLGKGMVIPSLPTSEAVFLAAGVLGATIMPHVIYLHSSLTQHLHGGSRQQRYSATKWDVAIAMTIAGFVNLAMMATAAAAFHFSGHTGVADLDEAYLTLQPLLSHAAATVFGLSLVAAGLSSTVVGTLAGQVVMQGFIRFHIPLWVRRTVTMLPSFIVILMGLDPTRILVMSQVLLSFGIALALVPLLIFTSDSKLMGDLVNSKRVKQTGWVIVVLVVALNIWLLVGTALGL
What is the function of this protein?
H(+)-stimulated, divalent metal cation uptake system.
What are the official names of this protein?
Divalent metal cation transporter MntH.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LEU32_BORBR
Sequence: MTHQIAVLPGDGIGPEIVEQAERVLKALDLPLELRQAPVGGAAFDQFEHPLPPATLELAQGSHAVLFGAVGDWKYDTLPREFRPEQAILGLRKALGLFANLRPAILYPELASASSLKPEIVSGLDILIIRELTGDIYFGTPRGVRTAADGAFAGEREGYDTMRYAESEVRRIARIGFESARKRNKKLCSVDKANVLETSQFWRDLVIEVSRDYPDVELSHMYVDNAAMQLVRNPRQFDVIVTGNLFGDILSDEAAMLTGSIGMLPSASLNAAGQGLYEPSHGSAPDIAGQGIANPLATILSAAMLLRYSLNLAPQADRVEAAVRKVLADGLRTADIHEAGTTKVSTSQMGDAVLKALG
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase 2, 3-IPM-DH 2, Beta-IPM dehydrogenase 2, IMDH 2.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: N2B_HAEIR
Sequence: MLSPKVLVRLVDSQQQILLLSSALCSPQQLSRRFLTPMQAYEQRIESKELLPDKVQKKTTQELEDLYNTLKNYQPKPVRVETSSGGGFFGRFMKKEQSAPKIELLNTTAPKGMYIYGSVGGGKTTLMDMFYSCCDDIPKKQRVHFNSFMSKVHGLIHKVKQERGPQDRAFNSEKPLPFDPTLPVAEMIANESWLICFDEFQVTDIADAMILKSLFTHLFNEGIVCIATSNRHPNDLYKNGLQRSNFIPFIGVLLNRCNVAAMDSGVDYRRIAQSGDTNYFVTTQTDAKSQMERMFKILCSQENDIIRPRTITHFGRDLTFQRTCGQVLDSNFEELCNRPLGGSDYIQIGQFFHTVLIHDVPQLTLLLKSQMRRFITLIDTLYDNRVRVVISAEVPLDQLFSFTDKPKDLADEQRMLMDDLKLGDTDTSASVFTGEEEMFAFDRTISRLYEMQKKEYWEQWAKHR
What are the official names of this protein?
Putative ATPase N2B, HFN2B.
What is the protein family that this protein belongs to?
Belongs to the AFG1 ATPase family.
Protein: MIP_CANLF
Sequence: MWELRSASFWRAIFAEFFATLFYVFFGLGASLRWTPGPLHVLQVALAFGLALATLVQAVGHISGAHVNPAVTFAFLVGSQMSLLRAFCYMAAQLLGAVAGAAVLYSVTPPAVRGNLALNTLHPGVSVGQATTVEIFLTLQFVLCIFATYDERRNGRLGSVALAVGFSLTLGHLFGMYYTGAGMNPARSFAPAILTRNFTNHWVYWVGPIIGGGLGSLLYDFLLFPRLKSVSERLSILKGARPSDSNGQPEGTGEPVELKTQAL
What is the function of this protein?
Water channel.  Channel activity is down-regulated by CALM when cytoplasmic Ca(2+) levels are increased.  May be responsible for regulating the osmolarity of the lens.  Interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core.  Plays a role in cell-to-cell adhesion and facilitates gap junction coupling (By similarity).
What are the official names of this protein?
Lens fiber major intrinsic protein, Aquaporin-0.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Protein: PUR7_RICFE
Sequence: MKTQLYKGSSKILYSAEEDFLLIMAFSDNVTLESGEIIEISGKGVLNNNISSFLMDKLEMNGIENHFIEKINMREQLIQYVEVFPVQVIISSVACGRFVKEFGMDEGYVFDKPIIDFKVRSREFKYPIVNEYQILNFGWLTRDEIKAVKEQALRIYDFLSGLFIGVGIRLVECKLEFGRVFNGEESIIMLTDEISPDNCRLWHINSNEKLGFELLENEPNKAFESYQLIADRLKEK
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: NT2NA_HUMAN
Sequence: MCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCLQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPETVRRGTELWERDREVWNGKEHDEN
What is the function of this protein?
Human-specific protein that promotes neural progenitor proliferation and evolutionary expansion of the brain neocortex by regulating the Notch signaling pathway (PubMed:29856954, PubMed:29856955, PubMed:29561261).  Able to promote neural progenitor self-renewal, possibly by down-regulating neuronal differentiation genes, thereby delaying the differentiation of neuronal progenitors and leading to an overall final increase in neuronal production (PubMed:29856954).  Acts by enhancing the Notch signaling pathway via two different mechanisms that probably work in parallel to reach the same effect (PubMed:29856954).  Enhances Notch signaling pathway in a non-cell-autonomous manner via direct interaction with NOTCH2 (PubMed:29856954).  Also promotes Notch signaling pathway in a cell-autonomous manner through inhibition of cis DLL1-NOTCH2 interactions, which promotes neuronal differentiation (By similarity).
What are the official names of this protein?
Notch homolog 2 N-terminal-like protein A, Notch homolog 2 N-terminal-like protein.
What is the protein family that this protein belongs to?
Belongs to the NOTCH family.
What are the subcellular locations of this protein?
Secreted. Cytoplasm.
Protein: MAON_SOLTU
Sequence: MWRVARSAASTFRRTRRLSTAISAPCIVHKRGADILHDPWFNKDTGFPMTERDRLGLRGLLPPRVISFEQQYDRFMESFRSLEKNTEGQPDSVVSLAKWRILNRLHDRNETLYYRVLIDNIKDFAPIIYTPTVGLVCQNYSGLFRRPRGMYFSAKDKGEMMSMIFNWPSTQVDMIVLTDGSRILGLGDLGVQGIGIPIGKLDMYVAAAGINPQRVLPVMLDVGTNNQKLLEDPLYLGLRQPRLEGEEYLSIVDEFVEAVHARWPKAVVQFEDFQAKWAFETLDRYRKKFCMFNDDIQGTAGVALAGLLGTVRAQGRPLTDFANQKIVVVGAGSAGLGVLKMALQAVSRMTGPSADPHFFLLDKNGLITKDRKDIDPAALPFAKAHHEIEGLGLQEGAGLAEVVKKVKPHVLLGLSGVGGIFHEEVLRAMKESDSVRPAIFAMSNPTNNAECCPVDAFKLAGEDIVFASGSPFANVDLGNGKIGHVNQANNMYLFPGIGLGALLSGARNISDTMLEAAAECLASYMSDDEINRGILYPSIDDIRDITAEVGAAVLRAAVAEDLAEGHGDVGVKELQHMSKEETIEHVRQNMWYPVYGPLVHE
What are the official names of this protein?
NAD-dependent malic enzyme 59 kDa isoform, mitochondrial, NAD-ME.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RF1_HYDS0
Sequence: MLPKNFLEKIQDIEQKYAQTEEKLASLDITKDADTYKALSKDLKELSYIHELYKDYNKILKDIEDTKELLKDKDLRELAEKELENLNTKLLQKEKELINVLTPKDANDSKNVILEIRAGAGGEEAALFAADLLRMYQRYAERKGWKFNILEANKTGLGGYKEVIVSIEGKNVYSHLKYESGVHRVQRVPITESGGRIHTSTITVAVLPEADETDVVINPQDLRIETFRASGAGGQYVNTTESAVRITHIPTGISISCQDERSQLQNKLKAMRILYARLKDFYEKQKKEETDKERKEQVGTGERSEKIRTYNFSQNRVTDHRINLTLHKLQDVLDGDLDDIISSLQAKELEEKLASA
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPD_PROM0
Sequence: MHFLIPAAGSGSRMKAGKNKLLIDLEGESLIYWTLKSVFSASSTNWVGIIGQPKDKNLLLNSTKDFAHKVHWINGGDTRQQSVFNGLKALPKDAEKVLIHDGARCLINPELIDLCAKQLDENEAVILATKVTDTIKIVDNEGFIKETPDRNYLWAAQTPQGFLVDRLKKAHKMAIDKNWNVTDDASLFEMLNWKVKIIEGTYSNIKITSPIDLKIAKLFVKNP
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: PYVG_ASPV1
Sequence: MAHLLTNSPIGLLGRWLSGGRLLPPTEQQPGFQLPPPYRLAATRTQPQQQQEQEQEQEQAKPATRPPWNEPQITAEGAIQVGWYSSTDPDNPQNWSFGAKLLVYLEVNLITFMVYMSVAIFSAAEGEFRTVFGVSRSVTELGMSLYVLGYGTGPMIWSPLSEIPSVGRNPPYVVSVTIFLLLSIPTAVVNNVPGFLILRFLQGFFGSPGLATGGASIADVTGLTHLPYGLYVWAVCSIAGPAVAPVIAGFSVPVKGWHWSMWEVLWAAGGCFVFLLFLPETSGPAILHLRAQRLRALTGNPAFQSQSEIAVRDARPTQIVYDALVIPWKINALDPAILFTTVYIGLVYAIFYSYFEVLPRVYITMHAMTLGQLGLIFLGAIVGTLLVLPGYFAFTHWSLNADFRRGVWPRPEKRLVPALCGSVLVPVGLFLFAWTARPDLHWVVPTVGLVLEVAGMSLVIQCVFSYVAVAYLRYSASLFAINDLARAYLAFAAIMWSDPLYDRLGVARGTTLLAGLTVGCVGGMFTLYWWGPALRKRSRFASD
What is the function of this protein?
MFS-type transporter; part of the gene cluster that mediates the biosynthesis of pyranoviolin A, a pyranonigrin analog with a C-3 methoxy group (PubMed:33117309).  May be involved in the secretion of pyranoviolin A (Probable).
What are the official names of this protein?
MFS-type transporter pyvG, Pyranoviolin A biosynthesis cluster protein G.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. CAR1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MNTR_SALTY
Sequence: MGRRAGTPTTKKVTQLVNVEEHVEGFRQVREAHRRELIDDYVELISDLIIEVGEARQVDMAARLGVSQPTVAKMLKRLASLGFIQMIPWRGVFLTPEGEKLAQESRERHQIVENFLLVLGVSPEIARRDAEGMEHHVSQETLDAFLAFTQQHGTSAE
What is the function of this protein?
In the presence of manganese, represses expression of mntH and mntS.  Up-regulates expression of mntP (By similarity).
What are the official names of this protein?
Transcriptional regulator MntR, Manganese transport regulator.
What is the protein family that this protein belongs to?
Belongs to the DtxR/MntR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK32_GOSBA
Sequence: MAVPKKRTSTSKKRIRKNVWKKKGYWAALKAFSLAKSLSTGNSKSFFVRQINLE
What are the official names of this protein?
50S ribosomal protein L32, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NCPP_SALPA
Sequence: MHQVISATTNPAKIQAILQAFEEIFGEGSCHITPVAVESGVPEQPFGSEETRAGARNRVGNARRLHPQADFWVAIEAGIDDDATFSWVVIDNGVQRGEARSATLPLPAVILDRVRQGEALGPVMSQYTGIDEIGRKEGAIGVFTAGKLTRSSVYYQAVILALSPFHNAVYR
What is the function of this protein?
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives.  Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine/xanthosine triphosphatase, ITPase/XTPase, Non-canonical purine NTP phosphatase, Non-standard purine NTP phosphatase, Nucleoside-triphosphate phosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the YjjX NTPase family.
Protein: ABHEB_PONAB
Sequence: MAASVEQREDTIQVQGQALFFREARPGSGQAHFSVLLLHGIRFSSETWQNLGTLHQLAQAGYRAVAIDLPGLGRSKEAAAPAPIGELAPGSFLAAVVDALELGPPVVISPSLSGMYSLPFLTAPGSQLLGYVPVAPICTDKINAANYASVKTPALIVYGDQDPMGQTSFEHLKQLPNHRVLIMKGAGHPCYLDKPEEWHTGLLDFLQGLQ
What is the function of this protein?
Acts as an atypical protein-lysine deacetylase in vitro.  Catalyzes the deacetylation of lysine residues using CoA as substrate, generating acetyl-CoA and the free amine of protein-lysine residues.  Additional experiments are however required to confirm the protein-lysine deacetylase activity in vivo.  Has hydrolase activity towards various surrogate p-nitrophenyl (pNp) substrates, such as pNp-butyrate, pNp-acetate and pNp-octanoate in vitro, with a strong preference for pNp-acetate.  May activate transcription.
What are the official names of this protein?
Putative protein-lysine deacylase ABHD14B, Alpha/beta hydrolase domain-containing protein 14B, Abhydrolase domain-containing protein 14B.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. ABHD14 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic.
Protein: GLGX_ECOUT
Sequence: MTQLAIGKPTPLGAHYDGQGVNFTLFSAHAERVELCVFDANGQEHRYDLPGHSGDIWHGYLPDARPGLRYGYRVHGPWQPAEGHRFNPAKLLIDPCARQIDGEFKDNPLLHAGHNEPDYRDNASIAPKCVVVVDHYDWEDDAPPRMPWGCTIIYEAHVKGLTYLHPEIPVEIRGTYKALGHPVMINYLKQLGITALELLPVAQFASEPRLQRMGLSNYWGYNPVAMFALHPAYACSPETALDEFRDAIKALHKAGIEVILDIVLNHSAELDLDGPLFSLRGIDNRSYYWIREDGDYHNWTGCGNTLNLSHPAVVDYASACLRYWVETCHVDGFRFDLAAVMGRTPEFRQDALLFTAIQNCPVLSQVKLIAEPWDIAPGGYQVGNFPPLFAEWNDHFRDAARRFWLHYDLPLGAFAGRFAASSDVFKRNGRLPSAAINLVTAHDGFTLRDCVCFNHKHNEANGEENRDGTNNNYSNNHGKEGLGGTLDLVERRRDSIHALLTTLLLSQGTPMLLAGDEHGHSQRGNNNAYCQDNQLTWLDWSQASSGLTAFTAALIHLRKRIPALMENRWWEEGDGNVRWLNRYAQPLSTDEWQNGPKQLQILLSDRFLIAINATLEVTEIVLPAGEWHAIPPFAGEDNPVITAVWQGPAHGLCVFQR
What is the function of this protein?
Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin.
What are the official names of this protein?
Glycogen debranching enzyme, Limit dextrin alpha-1,6-maltotetraose-hydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: YDFE_BACSU
Sequence: MDIKKQDTRRFKEIKPKIMYYGTSTFLLTTLNEDGTTNISPMSSSWALGHYIILGVGLGGKAIDNLERHKECVINLPGPDLWENVERISSYSGKKSIPPLKKQIGFTYKKEKYEAAGLTPLQSKTVSPTRIKECPIQIEAEVKHIRLPEYESSFAIVETQALHFHAEESIILDENHINPSKWSPLIYNFRHYFGLGREVGKTFRSET
What are the official names of this protein?
Uncharacterized protein YdfE.
What is the protein family that this protein belongs to?
Belongs to the flavoredoxin family.
Protein: RS7_OPITP
Sequence: MSRRHRAVKRQVEPDIRYKSPLVAHLVNVIMKSGKKNLAQRIVYGAFEKVSEKLEKGDPVDLLLGALENARPRLEVKSRRVGGATYQVPIEISFERQESLALRWIVDAASGRKGIPMKEALAAEIIDAYNNTGNVVKKKEDTHKMAQANRAFAHLRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: PDXH_NITHX
Sequence: MNDTSDIKHTSQLTSGDFTEASEPFALFAAWFAEAVASEPNDPDAMALATADADGLPDVRMVLMKGYDTQGFVFYSHIASAKGRELAANPKAALLFHWKSLRRQVRLRGPVTPVTDAEADAYFATRPKQAQIGAWASKQSQPLESRFAFEQAIAKQAAKYIIGSVPRPPGWRGWRITPAQFEFWHDRPFRLHDRIEFRRTAPDAPWTKTRLYP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: LUTA_BACVZ
Sequence: MKVSLFVTCLVDMFQTNVGKATVEVLERLGCEVDFPEGQICCGQPAYNSGYVTDAKKAMKRMIAAFEEAEYVVSPSGSCTTMFREYPHLFQDDPKWAAKAQQLADKTYELTDFIVNVLGVEDVGAVLHKKATVHTSCHMTRLLGVSEEPMKLLRHVKGLELTALPGKHQCCGFGGTFSVKMAQISEQMVDEKVACVEDTEAEVLIGADCGCLMNIGGRLDRKDKNVRVMHIAEVLNSR
What is the function of this protein?
Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source.
What are the official names of this protein?
Lactate utilization protein A.
What is the protein family that this protein belongs to?
Belongs to the LutA/YkgE family.
Protein: RL10_BEII9
Sequence: MDRAEKKESVAALADVFQKTSVVVVAHYSGLTVAQMQNLRKQMRASGATVQVAKNRLVKIALDGTPVSSISPLLKGPTLIAYSDDPVAAPKVAVGFAKDHDKFVILGGAMGTTALNVDGVRSLATMPSLDELRGKLVGLIQAPATKLAQLTTAPAAKLARVFGAYAAKDDAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: CUTC_ENT38
Sequence: MALLEICCYSAECAVTAQQYGADRIELCAAPKEGGLTPSYGVLKSVRQTVTIPVHPIIRPRGGDFFYSAGEFDAMLEDIAMVHDLGFPGLVLGLLDEDGNVDMPRMRQVMTAAKGMAVTFHRAFDMCRNPRQAFDKLAELGVARILTSGQESSAEKGIKLITELKAQSGVPIIMAGAGVRASNLEIFINAGVEELHSSAGKWTPSPMRYRNTGLSMSTDAEADEYSRYGVEGESVAVMKSIIERHHV
What are the official names of this protein?
PF03932 family protein CutC.
What is the protein family that this protein belongs to?
Belongs to the CutC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_BIFLD
Sequence: MANVTLNVTDAKGQATGTVEAPEALFGVSAEDVQAHIPLIHQVVTAQLAAARQGTHATKTRGMVSGGGKKPWKQKGTGRARQGSIRAPQWYHGGTVFGPQPRDYSQRTPKKMKAAALRYALSDRANAGRVAVVEFGITEPSTKAAVAALAPITADKFTTVVFTRDNINEWLSVRNIPTVHPIFVDQLNTYDVITSQYVVFTKEAFEAFVAAKTEPKEA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: GEX3_ARATH
Sequence: MVAFRFVYIPLPFFFFFFFFFVFFSGVSQLQDQTATKKSVRILSKILIGDDGRVYACSDNDFFSFESNGSIAWSVHMNFKCNTDFAPVYSGFNQMLLLAENRILRVIFPRNGTKSEPELFFDPGETILGFAVSVSSSSVYITVKNHGLYAYNMFRQQLWIAEPKIERFGYRLGCRKDFDNCTFNSRPVIDSCEGSIYISNNEGELYSLSLRGTYYQWIQDFSLVDRFFTVTPGNNGLVYVVFPIKSLVFALDSFSGDILWQKTIGPLAETSASDPVIDSNSWASIGSLDGTLYSFSRTGDLYKIPKNAETDSVIQIEPLLDCSGYAVYVSQTKFEGMIDRVIEDYTYVSAKKPETAVFSLVVPETRSIYWSQSYSDQIPGLLLDEDLQHFVLDERIALAFVAASSSGNPFRCRSKHEKLSSSCSFAEPEHLDIYIGNERAIIWFLLFEFVIMVLFAALVRFCFIFWKKKKLQDRPFSTFLDKRRLLHRKSREIDKTITRLQNESTANESAVDKIGDLIQKRENVKRKLSSTYSLGRDIDESKSKLKDYVLPLYGGSSRSFSYRNRENESITIFQTPSDESSSEESYRDEHYDDVADDEHDEDDLDRKQKGKLLAHSEGSSNDGDGIASSRRSIYLKHIFDD
What is the function of this protein?
Required for micropylar pollen tube guidance.  Plays a role during early embryo patterning.
What are the official names of this protein?
Protein GAMETE EXPRESSED 3.