PharMolix/UniProtQA huggingface dataset:
Protein: ZN227_HUMAN
Sequence: MPSQNYDLPQKKQEKMTKFQEAVTFKDVAVVFSREELRLLDLTQRKLYRDVMVENFKNLVAVGHLPFQPDMVSQLEAEEKLWMMETETQRSSKHQNKMETLQKFALKYLSNQELSCWQIWKQVASELTRCLQGKSSQLLQGDSIQVSENENNIMNPKGDSSIYIENQEFPFWRTQHSCGNTYLSESQIQSRGKQIDVKNNLQIHEDFMKKSPFHEHIKTDTEPKPCKGNEYGKIISDGSNQKLPLGEKPHPCGECGRGFSYSPRLPLHPNVHTGEKCFSQSSHLRTHQRIHPGEKLNRCHESGDCFNKSSFHSYQSNHTGEKSYRCDSCGKGFSSSTGLIIHYRTHTGEKPYKCEECGKCFSQSSNFQCHQRVHTEEKPYKCEECGKGFGWSVNLRVHQRVHRGEKPYKCEECGKGFTQAAHFHIHQRVHTGEKPYKCDVCGKGFSHNSPLICHRRVHTGEKPYKCEACGKGFTRNTDLHIHFRVHTGEKPYKCKECGKGFSQASNLQVHQNVHTGEKRFKCETCGKGFSQSSKLQTHQRVHTGEKPYRCDVCGKDFSYSSNLKLHQVIHTGEKPYKCEECGKGFSWRSNLHAHQRVHSGEKPYKCEQCDKSFSQAIDFRVHQRVHTGEKPYKCGVCGKGFSQSSGLQSHQRVHTGEKPYKCDVCGKGFRYSSQFIYHQRGHTGEKPYKCEECGKGFGRSLNLRHHQRVHTGEKPHICEECGKAFSLPSNLRVHLGVHTREKLFKCEECGKGFSQSARLEAHQRVHTGEKPYKCDICDKDFRHRSRLTYHQKVHTGKKL
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 227.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PROB_PSYA2
Sequence: MAVGIENTIEEARFVEQARNFDIQRVIVKIGSSLLTNNGRGLDRTAIYEWAKQIAKLHKQGIEVLLVSSGAVAEGVVRMNLEERPKKLAALQACASIGQMGLIETWWSALIQHGIQSSQLLLTHDDLSNRSRYLNTTGALTQLLEWRVLPVINENDTITIDEIKFGDNDTLGAMAAAMVNADLYIILTDQEGVFTDNPRDNPNAKMIRQERAMADYLFDIAGDGGKLGRGGMLTKIRAGRLAAMGGCPTVIVSGAIDDVITRVVSGEAVGTLLTTNDQDKIIARKQWLAAHLRMSGSLIVDAGAAKAVVEHQKSLLPVGVSEVRGDFDEGDVVEIVHQDTGERIAVGQVNFSSRDACRVARERTEQFDRILGNNEERVVMVHRDNLALTM
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RN121_CAEEL
Sequence: MGQHGAIRLQNEVQEGMPPPHELTEEEQWAEEHRKMHEKHKGHEAMHMEMMVIFMISVIVGQIFLVTWKRKHFKSYQMCTLIGMLTIPVYVCFNRSWYRFLATWLVFCIFSAFIWLKASAQHISGGTPRFVYKWFLFLHKLSYVLGVVGYLIMMGALLGFHVLFGVSQPTLMDAGILFMFYGVYYGVLGRDFAHICTARMASRIGYYTPEGLPKKHLEDGVCAVCGGRLDDSEHVHDADAVVTTKMVEDEDEKLYKLSCGHVFHEFCIRGWVVVGKLQTCPYCKERVDLQRMFKNPWEKPHLFYGKLLDWIRYLVCWQPLIVTAVQGLTTWMGLE
What is the function of this protein?
E3 ubiquitin ligase which accepts ubiquitin and transfers it to substrates such as the beta-integrin subunit pat-3, promoting their degradation by the endoplasmic reticulum-associated degradation (ERAD) pathway which is a pathway involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins (PubMed:20357004).  Negatively regulates the unfolded protein response to reduce endoplasmic reticulum stress (PubMed:20357004).  Required for the cessation of distal tip cell migration at the end of larval morphogenesis (PubMed:22285439).  Plays a role in germline and gonad development (PubMed:20357004).
What are the official names of this protein?
E3 ubiquitin ligase rnf-121, RING finger protein 121.
What is the protein family that this protein belongs to?
Belongs to the RNF121 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL28_SHEWM
Sequence: MSRVCQVTGKKPMVGNNRSHAKNATRRRFLPNLQNHRFWLEGEKRFVKLRISTKGMRIIDKKGIEVVVAELRARGEKV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: GTX3B_NEOIV
Sequence: GWRDWLKKGKEWIKAKGPGIVKAALKAAVQ
What is the function of this protein?
Shows a broad spectrum of activity against both Gram-positive and Gram-negative bacteria.  Has also antimicrobial activity against S. cerevisiae.  Has insecticidal and non-hemolytic activity.
What are the official names of this protein?
U1-poneritoxin-Ni3b, U1-PONTX-Ni3b, Poneratoxin, Ponericin Pi I2.
What is the protein family that this protein belongs to?
Belongs to the ponericin-G family.
What are the subcellular locations of this protein?
Secreted.
Protein: SPTCS_HUMAN
Sequence: MAAEEGVASAASAGGSWGTAAMGRVLPMLLVPVPAEAMGQLGSRAQLRTQPEALGSLTAAGSLQVLSLTPGSRGGGRCCLEGPFWHFLWEDSRNSSTPTEKPKLLALGENYELLIYEFNLKDGRCDATILYSCSREALQKLIDDQDISISLLSLRILSFHNNTSLLFINKCVILHIIFPERDAAIRVLNCFTLPLPAQAVDMIIDTQLCRGILFVLSSLGWIYIFDVVDGTYVAHVDLALHKEDMCNEQQQEPAKISSFTSLKVSQDLDVAVIVSSSNSAVALNLNLYFRQHPGHLLCERILEDLPIQGPKGVDEDDPVNSAYNMKLAKFSFQIDRSWKAQLSSLNETIKNSKLEVSCCAPWFQDILHLESPESGNHSTSVQSWAFIPQDIMHGQYNVLQKDHAKTSDPGRSWKIMHISEQEEPIELKCVSVTGFTALFTWEVERMGYTITLWDLETQGMQCFSLGTKCIPVDSSGDQQLCFVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDTLCHLNGWGRCSIPIHALEAGIENRQLDTVNFFLKSKENLFNPSSKSSVSDQFDHLSSHLYLRNVEELIPALDLLCSAIRESYSEPQSKHFSEQLLNLTLSFLNNQIKELFIHTEELDEHLQKGVNILTSYINELRTFMIKFPWKLTDAIDEYDVHENVPKVKESNIWKKLSFEEVIASAILNNKIPEAQTFFRIDSHSAQKLEELIGIGLNLVFDNLKKNNIKEASELLKNMGFDVKGQLLKICFYTTNKNIRDFLVEILKEKNYFSEKEKRTIDFVHQVEKLYLGHFQENMQIQSFPRYWIKEQDFFKHKSVLDSFLKYDCKDEFNKQDHRIVLNWALWWDQLTQESILLPRISPEEYKSYSPEALWRYLTARHDWLNIILWIGEFQTQHSYASLQQNKWPLLTVDVINQNTSCNNYMRNEILDKLARNGVFLASELEDFECFLLRLSRIGGVIQDTLPVQNYKTKEGWDFHSQFILYCLEHSLQHLLYVYLDCYKLSPENCPFLEKKELHEAHPWFEFLVQCRQVASNLTDPKLIFQASLANAQILIPTNQASVSSMLLEGHTLLALATTMYSPGGVSQVVQNEENENCLKKVDPQLLKMALTPYPKLKTALFPQCTPPSVLPSDITIYHLIQSLSPFDPSRLFGWQSANTLAIGDAWSHLPHFSSPDLVNKYAIVERLNFAYYLHNGRPSFAFGTFLVQELIKSKTPKQLIQQVGNEAYVIGLSSFHIPSIGAACVCFLELLGLDSLKLRVDMKVANIILSYKCRNEDAQYSFIRESVAEKLSKLADGEKTTTEELLVLLEEGTWNSIQQQEIKRLSSESSSQWALVVQFCRLHNMKLSISYLRECAKANDWLQFIIHSQLHNYHPAEVKSLIQYFSPVIQDHLRLAFENLPSVPTSKMDSDQVCNKCPQELQGSKQEMTDLFEILLQCSEEPDSWHWLLVEAVKQQAPILSVLASCLQGASAISCLCVWIITSVEDNVATEAMGHIQDSTEDHTWNLEDLSVIWRTLLTRQKSKTLIRGFQLFFKDSPLLLVMEMYELCMFFRNYKEAEAKLLEFQKSLETLNTAATKVHPVIPAMWLEDQVCFLLKLMLQQCKTQYELGKLLQLFVEREHLFSDGPDVKKLCILCQILKDTSIAINHTIITSYSIENLQHECRSILERLQTDGQFALARRVAELAELPVDNLVIKEITQEMQTLKHIEQWSLKQARIDFWKKCHENFKKNSISSKAASSFFSTQAHVACEHPTGWSSMEERHLLLTLAGHWLAQEDVVPLDKLEELEKQIWLCRITQHTLGRNQEETEPRFSRQISTSGELSFDSLASEFSFSKLAALNTSKYLELNSLPSKETCENRLDWKEQESLNFLIGRLLDDGCVHEASRVCRYFHFYNPDVALVLHCRALASGEASMEDLHPEIHALLQSAELLEEEAPDIPLRRVHSTSSLDSQKFVTVPSSNEVVTNLEVLTSKCLHGKNYCRQVLCLYDLAKELGCSYTDVAAQDGEAMLRKILASQQPDRCKRAQAFISTQGLKPDTVAELVAEEVTRELLTSSQGTGHKQMFNPTEESQTFLQLTTLCQDRTLVGMKLLDKISSVPHGELSCTTELLILAHHCFTLTCHMEGIIRVLQAAHMLTDNHLAPSEEYGLVVRLLTGIGRYNEMTYIFDLLHKKHYFEVLMRKKLDPSGTLKTALLDYIKRCRPGDSEKHNMIALCFSMCREIGENHEAAARIQLKLIESQPWEDSLKDGHQLKQLLLKALTLMLDAAESYAKDSCVRQAQHCQRLTKLITLQIHFLNTGQNTMLINLGRHKLMDCILALPRFYQASIVAEAYDFVPDWAEILYQQVILKGDFNYLEEFKQQRLLKSSIFEEISKKYKQHQPTDMVMENLKKLLTYCEDVYLYYKLAYEHKFYEIVNVLLKDPQTGCCLKDMLAG
What is the function of this protein?
May play a role in neurite plasticity by maintaining cytoskeleton stability and regulating synaptic vesicle transport.
What are the official names of this protein?
Spatacsin, Colorectal carcinoma-associated protein, Spastic paraplegia 11 protein.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Cell projection, axon. Cell projection, dendrite. Note=Mainly cytoplasmic.
Protein: MIAB_SULDN
Sequence: MQGMKKLFIETLGCAMNSRDSEHMIAELSEKEGYETTNDLSSADLIIINTCSVREKPVAKLFSELGVFNKRKKEGAKIGVCGCTASHLGEEIIKRAPYVSFVLGARNVSKISEVLHKERAVEIDINYDESEFAFNDFRTSPYKAYINISIGCDKSCTYCIVPKTRGEEISIPTELILREAQKAVKGGAKEIFLLGQNVNNYGRRFSGEHEKVSFSELLRRLSKIDALERIRFTSPHPFHMDDEFIEEFSSNPKICKSMHMPLQSGSSKVLKDMKRGYTKEWFLNRVQKLRAMSPDVSISTDIIVAFPGESDEDFEETLSIMREVKFDQIFSFKYSPRPETEAEHFTNIVDEDVASSRLTTLQNLAVNILDEKNKTHLGKIYRVYFEDLNQDYYASGRSDNNLLIKVKGSDELLGEFRDVKITDIGRTILSGEIVG
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLV_CAMJD
Sequence: MFHATTILAYKGKNKSVIGGDGQVSFGNTVLKGNAIKIRKLNNGKVLAGFAGSTADAFNLFDMFENLLQSSKGDLLKAAIDFSKEWRKDKYLRKLEAMMLVLDRNHIFLLSGTGDVVEPEDGQIAAIGSGGNYALSAARALAKHANLDEEELVKSSLQIAGEICIYTNTNIKTYVIEDEK
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEXI2_BOVIN
Sequence: MKDWEQKKVASPNQPPPAALEEAKISGTCGSPRTSPEPHDPGGSQPLTPRMESHSEEEDRPGAGGGLGWNGRSPRTQSLGACSAEAMLARKKHRRRPSKRKRHWRPYLELSWAEKQQRDERQSQRASRVREEMFAKGQPVAPYNTTQFLMNDRDPEEPNLVPQGASHPGSSGESEAGDSDGQGRARGEFQQKDFSEAYERYHTESLQGRSKEELVRDYLDLERRLSQAEEEMRRLRQLRGCTNWRPCYQVEELAAEVERLRTENQRLRQENEMWNREGGRRGGQPGS
What is the function of this protein?
Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor.  Core component of the 7SK RNP complex: in cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.
What are the official names of this protein?
Protein HEXIM2.
What is the protein family that this protein belongs to?
Belongs to the HEXIM family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MTRA_MYCBO
Sequence: MDTMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDGTQALTAVRELRPDLVLLDLMLPGMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYIMKPFKPKELVARVRARLRRNDDEPAEMLSIADVEIDVPAHKVTRNGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVWGYRHPADTRLVNVHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP
What is the function of this protein?
Member of the two-component regulatory system MtrA/MtrB.
What are the official names of this protein?
DNA-binding response regulator MtrA.
Protein: TRHO_PSEPG
Sequence: MSQAIVVAALYKFVTLEDYIELREPLLQAMLDNNVKGTLLLAHEGINGTVSATREGIDGLLAWLRNDPRLVDVDHKESYCDEQPFYRTKVKLKKEIVTLGVPGVDPNQAVGTYVEPKDWNALISDPEVLLIDTRNDYEVAIGTFKGAIDPKTETFREFPEYIKANFDPSKHKKVAMFCTGGIRCEKASSYMLGEGFDAVYHLKGGILKYFEEVPQEESLWDGDCFVFDNRVTVRHDLSEGEYDQCHACRHPINAQERASEHYSPGVSCPHCWDTLSEKTRRSAIDRQKQIELAKARNLPHPIGYNYKAEA
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: LPTD_BURPS
Sequence: MPPKTLFPLVPACDAAPRKKRLAVALLAVPGLVPAVSQAQLSGAAAEPQAFGSPWDLRLAPQLDEHPQKQGGKPATFVLADHTNGTAEQDLAAKGAAEIRRGNAAVKADAIHYDQDTDMADAYGKVTVANGGTTFSGPEAHLKVEANQGFMTTPKYRFTATGGTGSAERVQLLDSERSVFTNGTYTGCQCSTNPAWYIKGSEFDFDTGADEGVARNGVLFFQGVPLFGSPWLTFPLSGDRRSGFLPPTFSPFSSTNGFELSLPYYFNIAPNRDLTITPHIISKRGIFTQATFRYLSTNYSGTLTGEYLPDDRVAHRNRYAIFWQHQQNFGNGFGGYVYYNKVSDNLYPEELGSTNQFVNGVQTVYQQEAGLTYNNGPWSVLGRYQHWQTLPPSAAPYGREPQLNVKYTKYNVGGFDFGAEADYSRFRITTADQPEGDRVMFNPYVSYGLYGPGYFFVPKAQLHMASYDLTTTTGGVPGQPKRFTYSIPTLSLDTGLVFDRSVRLFGQDFIQTLEPRLFYVYTPYRNQSNAPLFDTAVSDFGLAEIFTPNTFVGNDRIADANRLTAALTTRFINPTTGDERARFVIAQQYYFTDQRVTLLPTEAPATARHSDLILGASVKLGAGFASETAFQYNVDNNQLVKSSVGFGYSPGERRVINVGYRYTRQNPTLSNEPINQILMSAQWPLTRRLYAVGRLNYDLASSRVVDGLVGFQYDADCWAFGVGVQRYANGLNSSGQQNSSTRVLAQLVLKGLTSIDNGLVTAFRAGVQGYTPLPPAPAPLSRFSNYD
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: RS13_RHIME
Sequence: MARIAGVNIPTAKRVVIALTYIHGIGTKFAQEIIEKVGIPAERRVHQLTDAEVLQIRETIDRDYQVEGDLRRETSMNIKRLMDLGCYRGLRHRRGLPVRGQRTHTNARTRKGPAKAIAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: DPO3B_MYCTO
Sequence: MDAATTRVGLTDLTFRLLRESFADAVSWVAKNLPARPAVPVLSGVLLTGSDNGLTISGFDYEVSAEAQVGAEIVSPGSVLVSGRLLSDITRALPNKPVDVHVEGNRVALTCGNARFSLPTMPVEDYPTLPTLPEETGLLPAELFAEAISQVAIAAGRDDTLPMLTGIRVEILGETVVLAATDRFRLAVRELKWSASSPDIEAAVLVPAKTLAEAAKAGIGGSDVRLSLGTGPGVGKDGLLGISGNGKRSTTRLLDAEFPKFRQLLPTEHTAVATMDVAELIEAIKLVALVADRGAQVRMEFADGSVRLSAGADDVGRAEEDLVVDYAGEPLTIAFNPTYLTDGLSSLRSERVSFGFTTAGKPALLRPVSGDDRPVAGLNGNGPFPAVSTDYVYLLMPVRLPG
What is the function of this protein?
Confers DNA tethering and processivity to DNA polymerases and other proteins.  Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA.  Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity.  The beta chain is required for initiation of replication as well as for processivity of DNA replication.
What are the official names of this protein?
Beta sliding clamp, Beta clamp, Sliding clamp, Beta-clamp processivity factor, DNA polymerase III beta sliding clamp subunit, DNA polymerase III subunit beta.
What is the protein family that this protein belongs to?
Belongs to the beta sliding clamp family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_STRA3
Sequence: MYVEMIDETGQVSEDIKKQTLDLLEFAAQKTGKENKEMAVTFVTNERSHELNLEYRDTDRPTDVISLEYKPEVDISFDEEDLAENPELAEMLEDFDSYIGELFISIDKAKEQAEEYGHSYEREMGFLAVHGFLHINGYDHYTPEEEKEMFSLQEEILTAYGLKRQ
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_PSEP1
Sequence: MPRRRVAAKREILDDPKYGSQILAKFMNHVMESGKKAVAERIVYGALDTVKARKNSDPLEIFEKALDAIAPLVEVKSRRVGGATYQVPVEVRPSRRNALAMRWLVDYARKRGEKSMALRLAGELLDAAEGKGAAVKKREDVHRMAEANKAFSHYRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: AROQ2_PSEAE
Sequence: MTRTVLVLNGPNLNLLGTREPQTYGRRTLGEIADECAAFAETRGFAVDFRQTNQEGQLLDWIHQARGRVAGIVINPAAWTHTSVALRDALAAVELPVVEVHLSNVHQREAFRHHSYVSPVALGVICGFGSLGYRLALEHFAERFEAAA
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase 2, 3-dehydroquinase 2, Type II DHQase 2.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: SECA_SYNP6
Sequence: MLNLLLGDPNVRKVKKYKPLVTEINLLEEDIEPLSDKDLIAKTAEFRQKLDKVSHSPAAEKELLAELLPEAFAVMREASKRVLGLRHFDVQMIGGMILHDGQIAEMKTGEGKTLVATLPSYLNALSGKGAHVVTVNDYLARRDAEWMGQVHRFLGLSVGLIQQGMSPEERRRNYNCDITYATNSELGFDYLRDNMAAVIEEVVQRPFNYAVIDEVDSILIDEARTPLIISGQVDRPSEKYMRASEVAALLQRSTNTDSEEEPDGDYEVDEKGRNVLLTDQGFINAEQLLGVSDLFDSNDPWAHYIFNAIKAKELFIKDVNYIVRGGEIVIVDEFTGRVMPGRRWSDGLHQAVESKEGVEIQPETQTLASITYQNFFLLYPKLSGMTGTAKTEELEFEKTYKLEVTVVPTNRVSRRRDQPDVVYKTEIGKWRAIAADCAELHAEGRPVLVGTTSVEKSEFLSQLLNEQGIPHNLLNAKPENVEREAEIVAQAGRRGAVTISTNMAGRGTDIILGGNADYMARLKLREYWMPQLVSFEEDGFGIAGVAGLEGGRPAAQGFGSPNGQKPRKTWKASSDIFPAELSTEAEKLLKAAVDLGVKTYGGNSLSELVAEDKIATAAEKAPTDDPVIQKLREAYQQVRKEYEAVTKQEQAEVVELGGLHVIGTERHESRRVDNQLRGRAGRQGDPGSTRFFLSLEDNLLRIFGGDRVAKLMNAFRVEEDMPIESGMLTRSLEGAQKKVETYYYDIRKQVFEYDEVMNNQRRAIYAERRRVLEGRELKEQVIQYGERTMDEIVDAHINVDLPSEEWDLEKLVNKVKQFVYLLEDLEAKQLEDLSPEAIKIFLHEQLRIAYDLKEAQIDQIQPGLMRQAERYFILQQIDTLWREHLQAMEALRESVGLRGYGQKDPLLEYKSEGYELFLEMMTAIRRNVIYSMFMFDPQPQARPQAEVV
What is the function of this protein?
Probably participates in protein translocation into and across both the cytoplasmic and thylakoid membranes in cyanobacterial cells.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm.
Protein: DPHB_METLZ
Sequence: MLTFIGLGLFDEYDVSVRGLDAIKSADTVFLEVYTSVLMGAPIERLEAFYGKKITPLYREDVEIHADKILDAAEFGNAVFLTAGDSMVATTHSDLRIRAADRNIPTTIIHGASITTAVCGLSGLQNYRFGKSVSVPFPYGKWFPMTPIEVISANLKENLHTLVFLDIQKDKERYMKISEAVDLLEEQARRVDAGIPLYVGIARAGSPEPTVHAGNAEEMKAFDFGSPLHILIVPATLHEIEREYLERFAGLC
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine.  The three successive methylation reactions represent the second step of diphthamide biosynthesis.
What are the official names of this protein?
Diphthine synthase, Diphthamide biosynthesis methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the diphthine synthase family.
Protein: ECFA1_MYCMS
Sequence: MDNSAIFEEFNSKKISQDDLEATITSLNNYFVKLNDLNNQYINLIRQDNIDKIEKQNIRQQQKQVKVEIKKISATTKLFKQNLKLAESLYKKIKLTNNQDDINKAKHEVEIAKSMLLQLKEVINGQGKSIKLKKLSDIAIEINHLSFKYGPEFPNAIDDVSFTINQGEYVTIIGHNGSGKSTISKILIGVLNAQHGEIKIFGNIVNDHNIEQARKFLGIVFQNPDNQFIGSTVEADIAFGLENKRIDPKKMPDIILDSAKKVGMEWALKKEPLNLSGGQKQRVAIASTLALDPDIMIFDEATSMLDPKGKREIKEIMVQLRETRTKTILSITHDMDEILNADKVIVLDHGKLVRVAKPLEIVEDKDFLRNIQLDVPFVGLVREELEKKGIKIASTQNIDELVEQICKK
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA1, ECF transporter A component EcfA1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: DNAA_SHEAM
Sequence: MAVSLWQQCIGRLQDELSAQQFSMWIRPLQAEMEGDTLVLYAPNRFVLDWVRDKYINSINQFFTEQLGDNAPKLRFDIGSRPSAKPQAPAPAAVKAAAPQPKPGNSFVSQPEPAVSNHRSNINPTYQFDNFVEGKSNQLGKAAALQVAENPGGAYNPLFLYGGTGLGKTHLLHAVGNGIIKNNPNAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALFIDDIQFFANKDRSQEEFFHTFNALLEGNHQIILTSDRYPKEIDGVEDRLKSRFGWGLTVAIEPPELETRVAILMRKAQESGINLPDEVAFFIAKRLRSNVRELEGALNRVIANANFTGRPITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKMADMLSKRRSRSVARPRQMAMALSKELTNQSLPEIGDAFGGRDHTTVLHACRKIAQLREESHDIKEDYANLIRTLSS
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_STRPN
Sequence: MTRYKATISYDGYAFAGFQRQPHARSVQEEIEKTLTRLNKGQAITVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHCRYAKHSKTYEFTVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTASGTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQIDLILEKKDRQLAGPTAAPNGLYLKEIRYEE
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: HIS82_TRIV2
Sequence: MLPFIRSDLAQFTAYKPHPSSDTDAAVPAQLDRLDTNESPCDLPPELKQKLAWTFQQVIESNRYPDGGHEELKDAIAQYVNESANISSSPITAANISVGNGSDELIRSLLIATCLGAQGSILVANPTFSMYGILAQTLGIPVVTVSRNPENFEIDLTAAQSAIEQTQNPPIRVVFVVHPNSPTANPLTTNELRWLKSLSEQILVVVDEAYFEFSQTTLISELVQRPNWVILRTFSKAFRLAAMRVGYCVAHPEAIAILEKVRLPYNLPSFSITSALVALQNRAILLESIPQILNERAKLITALSKYPELAVAESAANFIFLQLKTDNKNSPDTALLNLHQQLKNSGTLVRQISGGLRITIGTPEENIRTLNHIQTALIKA
What are the official names of this protein?
Histidinol-phosphate aminotransferase 2, Imidazole acetol-phosphate transaminase 2.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: KUP_JANMA
Sequence: MASPDKKSSLAALTLAAVGIVYGDIGTSPLYTMKEVFSKEHGLALTPENLLGVVSLIVWGLIIIVSLKYVTLVLRANNRGEGGIMALMALALSSVTRNSRWYFPLLVMGLFGATLFYGDSVITPAISVLSAIEGLSVATETFDPYVVPLTVAVLVGLYSVQARGTAGIGKWFGPIMVVWFATLAVMGVVNIIDAPEILYALNPWHALHFLDGNRFLAFIALGAVVLAFTGAEALYADMGHFGAKPIRMAWFLVAFPALALNYLGQGALLLMHPDAVTNPFYQQLGAWSIYPLVALSTMAAIIASQATISGTFSMTKQAIALGFLPRMKIEFTSASQIGQIYIPAVNWLQMAVVVMAVVGFGSSSDLAAAYGIAVTATMLVTTILTFFVIRYRWKYNLLLCLASTGFFLVIDLSLFSANMLKLFHGGWFPLLLGTILFTLMLTWKRGRELVFENLQKHAIPLEDFLASLFISPPTRVPGTAIFLRGESDGVPHAMLHNLSHNKVLHERVVFLTVRMMEVPYVPTTDQVRIHLLGDDCYQMDVTYGFKNVPDIPAALELAKDQGLEFEMMETSFFIARQTVVANPVRGMALWREHIFVAMSRHARGAADYYQIPSNRVIELGTKVEI
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RSMG_PEDPA
Sequence: MTPEEFKKALEDKGYQISDHQMAQFATYYKMLVETNEHVNLTAITEENEVYLKHFYDSVTPLLEAPEYFKSGAELCDVGAGAGFPSLPMKILFPSLKVTIVDSLNKRITFLKTLVDQLELTDVTLVHDRAETFGAKKSVYREKFEIVTARAVARLSVLSELCIPLVKQNGFFIALKAANTEQELSDGKMAIAILGGKLIVDKDFALPATGDERHLVVVEKKKQTPNKYPRKPGTPGKDPIGKK
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.