PharMolix/UniProtQA huggingface dataset:
Protein: DPOLA_LEIDO
Sequence: MSGGNDGASWRLSRKPNAPNFDETQEDQWRSLREEVLQSDEDENIPESGDLTIPQLPSAKKAAKKLRKPPSGAKPTPKPKQQTLAQSMSDMDMERLLKRYRIDEDIDIAEDIDMSHLLQLHSDSDDGGDAQEATLTADEFLARLARAEAAPAASIAKEKRESGENVTVVALKDELFNVERDQSAKPPRPRPTPGAGGGAGYRNEETPKQAIELTATLAPQMDAAQFVSPAVPYKSGEMTEGLFYWFDAREQPHTLSVDPGSLFLFGKMAVEKNGRTSYLSCCVRVRNMYRSVFVLPKAGSSQEDVVKEINDICRNQGIEQRRIKFVERYYAFEVPGVPHEKTQWAKLRYPGRYPPLNAKGPFRHILIIMGASSSLLELFLIKRKLKGPSFLRISGLVASANRISHCALEFSVESPKNLRAEDTKLPVPPFTLASIQIHTQLDSKGACNEILIASVAIYKDVNIENTIRYIPDNILTGVRPASMSTPLPIDLESYCSAKGLPGVRRFANERALLDWLAQQLGKIDADMMIGHNFLGFTLDILLRRYQELSISSWSTIGRLDLKRLPRFQGTATNVNQEKETCIGRLVVDSYSLSREHYKTVNYRLLSLADQMQLQGITKGSNNFEPGTSVLTPAMLSASRDIYDVLLQVCNCAVLSTAVVSHLDVIRLTKRLTTIAGNLWSRTLFGARSERIEYLLLHTFHDLKFITPDRYVQNFKRGRDDEEEEDGKRKAKYQGGMVLDPKCGLYSDYILLLDFNSLYPSLIQEFNICFTTVDRESGSEIDVPPPENLICASCAAAGLSAPCLHKCVLPKVIKSLVDSRREVKRLMKIEKDANNLALLEIRQKALKLTANSMYGCLGFEYSRFHAQPLAELVTRQGRLALQSTVDLIPQLNPSLRVIYGDTDSVMIQTGIKNDIKAVRDLGLDLKAKINKRYQSLEIDIDGVFRAILLLKKKKYAALTVTDWQGEGKTYKKEVKGLDMVRRDWCPLSKCVCDSVLSRVLNAEGSEDILDYVMNYMRDVSEKVRAGRYTLDNFVISKSLTKEPEAYRGNSFPHATVALRMKQRKELVRVGDLIPYVICTGDRLSDKAFHVEEVRQNSQLQIDSEWYLSVQIYPPVMRLCEHIQGFSNAQLSEAMGIACHTGAKLEEEEAETMNDFSHSSLFQSRNLEECFPAALSLQVACTHCRLMTPINPHTRVMEVLADQERQRDRFDLYVCVSCRKSLPVDYVANCFTQTCYGIIRQFYQCGSAAAVKAVRTQFTYYRALFDVPHAPGCPARVKDAHYYQARRCLGVDRRLYTLAEAADPAVQEVADPVDPLNAAAETIYKRIDHLFINLDSLFAGI
What is the function of this protein?
Polymerase alpha in a complex with DNA primase is a replicative polymerase.
What are the official names of this protein?
DNA polymerase alpha catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Nucleus.
Protein: WDL2_ARATH
Sequence: MGRELVDKHMDKKANSLTASSTGSSDDNKVPSPSTNEAAEVKECTEQNLVADDARLRQQGITETPGSHKSSVKPRVTAKTTVPKPFSLSAEKPRRAAVDNNSLGNGASHNSSSASRVSQLNSPLPTRRIPDHKMHHDEEDSFSVASSSATSIRSFKPKITIGVAPTFSSTSRLERRREFYQKLEEKQKALEAEKRENEKRLKEEQEAVTKQLRKNMAYKANPVPSFYQEGPPPKQPLKKFPLTRPKSPNLNRRKSCSDTVNASYQEVKGKHCARHRHSVGGCKDEVKTNSVPRTPNSSSKDQMRKSKKGTPKSEEVHEMFNSGHDGETGENGVGVVEE
What is the function of this protein?
Microtubule-associated protein (MAP) that regulates the orientation of interphase cortical microtubules.
What are the official names of this protein?
Protein WVD2-like 2.
What is the protein family that this protein belongs to?
Belongs to the TPX2 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: STA_BACSU
Sequence: MIMKMTHLNMKDFNKPNEPFVVFGRMIPAFENGVWTYTEERFSKPYFKQYEDDDMDVSYVEEEGKAAFLYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGAVDTMLYSNFPTANEIAIFWYYKF
What is the function of this protein?
Involved in resistance to streptothricin, a broad-spectrum antibiotic produced by streptomycetes.  Detoxifies streptothricin via acetylation of the beta amino group of the first beta-lysyl moiety of streptothricin.
What are the official names of this protein?
Streptothricin acetyltransferase A.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. GNAT subfamily.
Protein: CTU2_AEDAE
Sequence: MCSIGEDDFGDEGGVHAMKEESPLPEGATTIEQEICRKCNDQRAVLKLNQKEPQCRECFLHYVRHKFRASLGATKIVRRGSKVMVVFNGAPENVVMLDMVRHGLEQEAFKKLRVDPVVVFVGEDFIGRDQEGYEQSVREKVQILRQFGFPAYYTVLGAQDSCSIEDNCLAGKFIGDQDKVTKVLQGIKSITSKQDFIVQTRKQTYKAIAKKLECGYIFLSSIGLELAKTLLSDVSLGRGKSLALDIAFCDDRDEERKIIRPMRDLNPEEIEYYLKFAENQLQSVAIVDPYLDKSSLQNLTSKFVDGLQLSFPSTVSTVFRTGDKLGAEKIPTCDNQLEDDDHFATLFDKSLKLESNAEEPRKCKFCHSALDYRDSTTLFATEFSRMVSSRINVQLSHEEIIESTKLMEQDACKLVNAELEDDEMRQLKRELCHACRNILVDFDGK
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  May act by forming a heterodimer with NCS6/CTU1 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.
What are the official names of this protein?
Cytoplasmic tRNA 2-thiolation protein 2.
What is the protein family that this protein belongs to?
Belongs to the CTU2/NCS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MFS55_MYCS2
Sequence: MSSRGNRNIAISAGSLAVLLGALDTYVVITIIVDIMADVGIAINQIQQVTPIITGYLLGYIAAMPLLGRASDRFGRKMLIQVGLAGFAVGSVVTALSSDLTMLVIGRIIQGSASGALLPVTLALAADLWSARSRASVLGGVGAAQELGAVLGPMYGIALVWLFNHWQAVFWVNVPLAVIAMVMIHFSLPARQQVDEPERVDVIGGVLLAIALGLTVVGLYNPEPDGKQVLPSWGLPVLAGALVAAVAFFAWEKVAKTRLIDPAGVRFRPFLAALAASLCAGAALMVTLVNVELFGQGVLGQDQDHAAFLLLRFLIALPIGALIGGWLATRIGDRLVVLIGLLIAAGGFVLISHWSVDVLADRHNLGLFTLPVLDTDLAIVGLGLGLVIGPLTSATLRAVPAAEHGIASAAVVVARMIGMLIGIAALGAWGFYRFNQHLATLAARAAGDAGSPMSLAERLTAQAVRYREAYVMMYGDIFLSAAVVCVIGALLGLLISGKHEHAEEFEPAYAPTYGGGGAIDPYDAGDADDAPTEMLDLPTQVLSAPPSDPGDERPGRHRAP
What is the function of this protein?
In association with lipoprotein LprG probably transports triacyglycerides (TAG) across the inner cell membrane into the periplasm; TAG probably regulates lipid metabolism and growth regulation (By similarity).  Confers resistance to ethidium bromide, possibly acting as an efflux pump, requires LprG lipoprotein for normal function (PubMed:18156250).  Export of ethidium bromide can be complemented by the equivalent operon from M. tuberculosis (lprG-Rv1410c) (PubMed:18156250).
What are the official names of this protein?
Probable triacylglyceride transporter MSMEG_3069/MSMEI_2992, MFS-type drug efflux transporter P55.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SH3BG_DROME
Sequence: MVLKVYVSGMSGNKEVKKRQQRVLMILDSKNIKYDTVDITEPGKESEKELMQNKSTSNGGTVSDPEPRHPLPPQLFNDDEYCGDYDAFDMANEIDTLEVFLKLAPADTTAVSTAQIELKQENGDAKKEEAETEAEDKKTEAGDGDVDVKEEAAEKAEV
What are the official names of this protein?
SH3 domain-binding glutamic acid-rich protein homolog, SH3BGR protein.
What is the protein family that this protein belongs to?
Belongs to the SH3BGR family.
Protein: LEU1_PROMM
Sequence: MAKDPGRVLIFDTTLRDGEQSPGASLNLEEKLAIAQQLARLGVDVIEAGFPFASQGDFAAVQRIAQQVGGDEGPIICGLARASRADIKACADAVAPAPRRRIHTFIATSDIHLEHKLRKSRAEVLAIVPEMVAYARSLVDDVEFSCEDAARSDPEFLYEVIEAAIAAGAGTINIPDTVGFTTPSEFGALIAGIDCHVPNMNEAVISVHGHNDLGLAVANFLEAVKSGARQFECTINGIGERAGNAALEELVMALYVRRRYFNPFFGREPDSPTPLTAVRTEEITKTSRLVSNLTGMVVQPNKAIVGSNAFAHESGIHQDGVLKNRLTYEIVDARTVGLSDNRISLGKLSGRSAVRARLEELGYDLTREDLDEAFARFKDLADRKRDITDRDLEAIVSEQVQQSEARFQLRLVQVSCGSSLRPTATVILAQEDGQEQTAAAVGTGPVDAVCRALNALAGEPNELIEFSVKSVTEGIDAMGEVTIRLRRDGQLFSGHSADTDVVVAAAQAFVNALNRLVAGCGRQSLHPQHDAVLADLRSGI
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: SYA_CHLMU
Sequence: MLSNTLRSNFLKFYTNRNHTPVASSPVFPYNDPSILFTNAGMNQFKNIFLGKEQTSYTRATTSQKCIRAGGKHNDLENVGHTSRHLTFFEMLGNFSFGDYFKQDAISFAWEVSLSVFNFDPDFIYATVHEKDDEAFALWEKYLPTNRIFRLTDKDNFWSMADTGPCGFCSELLFDRGEKFGKATSPLEDADGERFLEYWNLVFMEFNRTSDGTLLALQKKCVDTGAGLERLVSLLSETDTVFEADVLRHLIAKVENLSEITYSPTESKGSAFRVIADHVRSLSFAITDGLLPGNTERGYVLRKILRRAVNYGKRLGFHRPFLAEIVPSLIETMGEAYPELQAAETQIQEVLTTEEEHFFKTLQRGGNLLHQVLKSSASLSKISGEDAFKLKDTYGLPIDEIALLAKDHNYTVDMDTFRKLEMEAKERSRKNTVKNKNDSDSIFQDVDPTNTSEFVGYDMLSCDTFIEGIVKYNEIASTLEEGEEGAIILRTTPFYAEKGGQVGDSGEIFCESGTFLVSHTTTPKAGLIAHHGKLSQGSLQTTMAVTAQVNQNLRKKIANNHTGCHLLHKALEVSLGEHIRQAGSYVDSQKIRLDFSHNKALSPEELLTIETLVNEKIRENVPVTIREALYSDVMNSSEIKQFFGDKYGDIVRVVSAGFSHELCGGTHARATGDIGYFRITKEHAVSTGIRRIEATTGEDAENIARGQDTDLNEIATIIQSPKDQLLVKLRNVMEEKKDLAKQLANLENQLVQQQVKSLLTSCDKVNETSYLVYHLTEEEGQRIQHYANTLHKEVPAKFISLWVTEKNDRYIVLVRVSDDLVKQGIDAQALLEELLAPYGGRCGGKAVSAQGSSKELPQIEVLNTILRQWISTRLA
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_STRMU
Sequence: MVVTDGVVSLKHLVSMEILSNEEVLGLIKRGLAFKEKKVTFSLDRQYFAANLFFEASTRTHKSFEVAEKKLGLDVIEFDAKTSSVNKGETLYDTILTMSALGVDICVVRHSQDDYYKELIDSRTIQTSIVNGGDGSGQHPSQCLLDLMTIYDEFASFENLKIAIAGDITHSRVAKSNMQILKRLGAQIYFAGPKEWYSSEFDVYGKYVAIDDIINQIDVMMLLRVQHERHDGKESFSKKAYHQHYGLTEERYKQLKSSAIIMHPAPVNRDVEIADSLVEAPKSRIVAQMKNGVFVRMAILEAILRGKT
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: PHCA_RALSO
Sequence: MVNVDTKLLVIFVELLSKRNATYVAEKMHMTAPAVSHSLGRLREIFDDPLFIRVPHGLTPTPKALELGPKVREMLDLWAAINEGDIATFDPLEAAGTFNISFAGTLGDALFDRFLLRVKRLAPGLQVRLTESSSWEADVAAMRSNELDLAFSPFPTRHPEIVEEVVTSFNMWVCARKDHPVLKDHCSLDQYLECEHIFIAQGNPGTRAAPSLIPLDYALQQRGLKRHSTMTVHAWRTQAEVAAQTDMIFTVNSLMKDLVCETYNLNAFPLPSELETVLGLNMLWHRSRNTHPMLVWARNLFKQVVAEYTGKASIAPMHPPMLTDDSGKSGKTGKGDAEKEDESRLSV
What is the function of this protein?
Regulates the transcription of one or more of the genes involved in virulence.
What are the official names of this protein?
HTH-type transcriptional regulator PhcA, Virulence genes transcriptional regulator PhcA.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: APT_ECO5E
Sequence: MTATAQQLEYLKNSIKSIQDYPKPGILFRDVTSLLEDPKAYALSIDLLVERYKNAGINKVVGTEARGFLFGAPVALGLGVGFVPVRKPGKLPRETISETYDLEYGTDQLEIHVDAIKPGDKVLVVDDLLATGGTIEATVKLIRRLGGEVADAAFIINLFDLGGEQRLEKQGITSYSLVPFPGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_STRAW
Sequence: MAKQIKGILGEKLGMTQVWDENNRVVPVTVVKAGPNVVTQVRTNDSDGYESVQIAFGEIDPRKVNKPLKGHFAKADVTPRRHLVEIRTADASEYTLGQEITAETFEAGVKVDVTGKSKGKGFAGVMKRHNFKGLGAGHGTQRKHRSPGSIGGCATPGRVFKGLRMAGRMGNERVTTQNLTVHAVDAEKGLLLIKGAVPGPNGGLVLVRTAAKGA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: SEC23_EMENI
Sequence: MDYEGLKDQWSDVEDRDGIRLSWNTFPSSRMEASRLVVPIGAIYTPLKERPDAPLLQYEPVTCKAPCRAVLNPYANVDVRARIWICPFCLMRNPLPPHYKDITESTIPPELHPLSTTIEYQLARPAPAPPIFVFVVDTCQEDDSLKAVKDSLILSLSLLPPNALVGLITFGTMAQVHELGYTECAKSYVFRGSKDYNAKQVQEMLGLASGIRPNMPNMPQQPVRPPLGAAARFLLPVQQAEFQITNMLEQLQRDPWPVANDKRPLRCTGVALNVAVGLLESSFQNAGAHIMLFTSGPATEGPGLVVSPELKEPIRSHHDIDRDNIKYYKKALKFYDALAKRAANNGHVVDLFAGCLDQVGLLEMKNLANYTGGHILLTDSFTSSQFKQSFIRVFDKDANDNLLMGFNASLEVLTTKELKVTGLIGHAVSLNKKSSSVGETECGIGNTCAWKMCGIDPSSSYGIYFEIANQGGPAAVQPGPQRGMMQFLTYYQHSSGHFHLRVTTVARNLSGPAGDPTLAQSFDQEAAAVLMARIGVFKAEVDDGPDVLRWVDRMLIRLCSRFADYRKDDPTSFRLEKNFTLYPQFMFHLRRSQFLQVFNNSPDETAFYRHVLNHEDVGDSLIMIQPTLDSYSLEHEGSLPVLLDSASIQPTHILLLDTFFHILIFHGETIAEWRKAGYQDQEGYENLKALLDLPKEDARELISERFPLPRFIVCDAGGSQARFLLSKLNPSTTHTTGGYGGGVSSQTIFTDDVSLQTFMDHLMKLAVSGTS
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
What are the official names of this protein?
Protein transport protein sec23.
What is the protein family that this protein belongs to?
Belongs to the SEC23/SEC24 family. SEC23 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GSA_SHIF8
Sequence: MSKSENLYSAARELIPGGVNSPVRAFTGVGGTPLFIEKADGAYLYDVDGKAYIDYVGSWGPMVLGHNHPAIRNAVIEAAERGLSFGAPTEMEVKMAQLVTELVPTMDMVRMVNSGTEATMSAIRLARGFTGRDKIIKFEGCYHGHADCLLVKAGSGALTLGQPNSPGVPADFAKHTLTCTYNDLASVRAAFEQYPQEIACIIVEPVAGNMNCVPPLPEFLPGLRALCDEFGALLIIDEVMTGFRVALAGAQDYFAVVPDLTCLGKIIGGGMPVGAFGGRRDVMDALAPTGPVYQAGTLSGNPIAMAAGFACLNEVAQPGIHETLDELTTRLAEGLLEAAEEAGIPLVVNHVGGMFGIFFTDAESVTCYQDVMACDVERFKRFFHMMLDEGVYLAPSAFEAGFMSVAHSMEDINNTIDAARRVFAKL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLME_SALDC
Sequence: MTGKKRSASSSRWLQEHFSDKYVQQAQKKGLRSRAWFKLDEIQQSDKLFKPGMTVVDLGAAPGGWSQYVVTQIGGKGRIIACDLLPMDPIVGVDFLQGDFRDELVMKALLERVGDSKVQVVMSDMAPNMSGTPAVDIPRAMYLVELALEMCRDVLAPGGSFVVKVFQGEGFDEYLREIRSLFTKVKVRKPDSSRARSREVYIVATGRK
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEA_SYNE7
Sequence: MNEPSPSDWHLDAYDYELPPDRIAQSAVEPRDHARLLVFPDREQLWHRHFYDLPQLLRPGDLLIVNDTRVIPARLYGQKIETGVPVEVLLVEEHGPGYWLTLVKPGKRLKPGSAIAFGPNPEDPLLVADVEASDPATGGRWLRFRGEAEAFWSQLATLGEMPLPPYIHTTASDPERYQTVYSRELGAVAAPTAGLHFTPELLTTLADMGIATAPVTLHVGIGTFRSVDVEDIRQHEMHSERMMVPAATVEKIQATKAAGGRVIAVGTTSVRAIEGAAASGELKPGSDRVNLFIYPGYRWQIIDGLITNFHLPRSSLMMLVSALIGRDRLLSAYATAIAEQYRFYSFGDAMLILPDAKLP
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_STRSY
Sequence: MSSGKITQVVGPVVDVAFAAEDKLPEINNALVVYKNDDSKQKVVLEVALELGDGVVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDLEESFPADFEREPIHKKAPAFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVGKTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEPPGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLTQLGIYPAVDPLASSSRALAPQIVGEEHYAVAMEVKRVLQRYQELQDIIAILGMDELSDEEKTLVGRARRIQFFLSQNFNVAEQFTGMPGSYVPVAETVKGFKEILDGKHDHLPEDAFRNVGSIEDVVAKAAKMKF
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HEMH_ERWT9
Sequence: MRQDKPGVLLVNLGTPDAPTTSAVKRYLKQFLSDKRVVDAPRWLWWPLLNFGILPIRSPRVSKLYASVWMDEGSPLMVYSQRQRNALAARLDMPVALGMSYGNPSLKSAIDSLMAEGVTRLIVLPLYPQFSCSTVAAVWDGITQVFAGYRSLPSVHFIRDYAQHPAYIAALKASVERSFAQHGKPDLLVTSFHGIPQRFADEGDDYPQRCYETFEALKASLGLGDDEAMLTFQSRFGREPWLMPYTDKTMESLPGKGVKHVQIMSPGFASDCLETLEEIDGENREIFLHAGGTRFEYIPALNDDEAHITMMLELVNQYR
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THM1_THADA
Sequence: MAATTCFFFLFPFLLLLTLSRAATFEIVNRCSYTVWAAASKGDAALDAGGRQLNSGESWTINVEPGTNGGKIWARTDCYFDDSGSGICKTGDCGGLLRCKRFGRPPTTLAEFSLNQYGKDYIDISNIKGFNVPMDFSPTTRGCRGVRCAADIVGQCPAKLKAPGGGCNDACTVFQTSEYCCTTGKCGPTEYSRFFKRLCPDAFSYVLDKPTTVTCPGSSNYRVTFCPTALELEDE
What is the function of this protein?
Taste-modifying protein; intensely sweet-tasting.  It is 100000 times sweeter than sucrose on a molar basis.
What are the official names of this protein?
Thaumatin I, Thaumatin-1.
What is the protein family that this protein belongs to?
Belongs to the thaumatin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle. Note=Thaumatin accumulates in vesicle-like organelles.
Protein: ABHD_DICDI
Sequence: MFSSRDKAEVKLYFDSNNEENQKILDQCPHLYQKYDKDVTINDRINNIEDSEPTIKNGVTFYPPYYLYNSHFMNYYGSYKIPKLNLKTRREILVNPIDGGTISLDFFELGEFKEDTPTIVINHGLTGGSHERYVQYFAQRAYKEKGFRSVVFNYRGCAGNPITADRAYSAVQLDDIKFVTEYLTKTALPLVKKWFLVGFSLGSAILVNYMADAGKDSPYLAHVSISNPMNMVECTKNLSSTYINNLIYNKGLANNLKRLFRKFDGRLDKYATKEQIMAAQTIADFDDLITSKMFGFETAHDYYLAASSSKSIRNLVKPILFINAIDDPIAPTSGFPWKDFKSNPNTILCVSRWGGHLGFISYEDHMSWSDKAAVEYLSTFLDDNNNNNDNDNKTE
What are the official names of this protein?
Abhydrolase domain-containing protein.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.
Protein: TM115_YEAST
Sequence: MQYSSRFLELNIPDSFLNINKIPDATKFITVTYICLTATLFCIRRSLYNKLVLEDPNLDYNLITSPLLQMVPSQIWRYPTSLVLSNFIDTKAWKVVVNLLNLIIGGSFIERNWNSSKEMFKFIIVLGSLTNVLIIMLTLLVSFFSNKVRLDIPLDGNYTILIGFPIIYRQLLPETTIIHLKTPQFLAKNFRFKLLPIFVMFTMTVTQIIWFHHFAQLFSIWVTFFASWSYLRFFQKLAPLNCPSLPTTNSQGGQEILVGDASDTFQLIYFFPDLIKPILRPIFNFIYNVVVVKFKVIKPFHDIDIDIGNTIAESRGAKKIMTVEERRRQLALQVLEERMVNP
What is the function of this protein?
May play a role in retrograde transport of proteins from the Golgi to the endoplasmic reticulum.
What are the official names of this protein?
Transmembrane protein 115 homolog.
What is the protein family that this protein belongs to?
Belongs to the TMEM115 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: CUZD1_MOUSE
Sequence: MEVTGRLFIWAILAVSCGAQLNSTEAEGKSRCTASLGGANLGETHKALVLQLSANENCTWTIERPENRSIRIIFSYIKLDPGSRCETENIKVFDGSSTSGPLLGKACSRNDFVPVFESSSNSMTFQIVTGLTKFPRSVFIFYYFFSAATVIPNCGGDLRALEGSFSSPNYPKPHPELAYCVWHIQVGKGYKIQLKFTDLLLEMDENCKFDFIAVYDGPSTTAGLLKQLCGRGKPTLESSSDAMTVVLSTDYANSYKGFSASYTSIYIHDVNTTSLSCVSDKMRVIISKSYLPALNYNESNLQLNDPTCRPNVSNVIEFSIPLHECGTVKKIEDHAISYTNRITFIESPVSAVITRQKLLQIVVTCEMEYNSTVEIMYITEDDIIQNQSVLGKYNTSLALYESDSFENLVQESPYYVDLNQTLFVQATLHTSDPSLVVFLDTCRASPTSDFASPTYDLISSGCCQDETCKVYPLFGHYGRFQFNAFKFLKHLNSVYLKCKILICDNNDQTSRCNQGCVPRRKRDIPSYKWKTDSVIGPIRLKRDRSASRDSGLLPQIHEAEISNQPLSRLYLFSFMVLALNVVIVAITTVKHFLNRWMDHRYQKLQVY
What is the function of this protein?
Localized to zymogen granules, where it functions in trypsinogen activation (PubMed:12401800).  May indirectly regulate cell motility, cell-cell and cell/extracellular matrix interactions (By similarity).
What are the official names of this protein?
CUB and zona pellucida-like domain-containing protein 1, CUB and ZP domain-containing protein 1, Integral membrane-associated protein 1.
What are the subcellular locations of this protein?
Zymogen granule membrane; Single-pass type I membrane protein.
Protein: ITIH3_PONAB
Sequence: MVALSHLGSALQLGSLWGFPRSPFRLLGKRSLPEGVANGIEVYSTKINSKVTSRFAHNVVTTRVVNHADTAKEVSFDVELPKTAFITNFTLTIDGVIYPGNVKEKEVAKKQYEKAVSQGKTAGLVKASGRKLEKFTVSVNVAAGSKVTFELTYEELLKRHKGKYEMYLKVQPKQLVKHFEIEVDIFEPQGISMLDAEASFITNDLLGSALTKSFSGKKGHVSFKPSLDQQRPCPTCTDSLLNGDFTITYDVNRESPGNVQIVNGYFVHFFAPQGLPVVPKNVAFVIDISGSMAGRKLEQTKEALLRILEDMKKEDYLNFILFSGDVSTWKEHLVQATPENLQEARTFVKSMEDKGMTNINDGLLRGISMLNKAREEHRVPERSTSIVIMLTDGDANVGESRPEKIQENVRNAIGGKFPLYNLGFGNNLNYNFLENMALENHGFARRIYEDSDADLQLQGFYEEVANPLLTGVEVEYPENAILDLTQNTYQHFYDGSEIVVAGRLVDEDMNSFKADVKGHGATNDLTFTEEVDMKEMEKALQERDYIFGNYIERLWAYLTIEQLLEKRKNAHGEEKENLTARALDLSLKYHFVTPLTSMVVTKPEDNEDERAIADKPGEDAEASYQPPQNPYYYVDGDPHFIIQVPEKDDALCFNIDEAPGTVLRLIQDPVTGLTVNGQIIGDKRGSPDSKTKKTYFGKLGIANAQMDFQVEVTTEKVTLWNRAVQSTFSWLDTVTVMQDGLSMMINRKNMVVSFGDGVTFVVVLHQVWKKHPVHRDFLGFYVVDSHRMSAQTHGLLGQFFQPFDFKVSDIRPGSDPTKPDATLLVKNHQLIVTRGSQKDYRKDASIGTKVVRWFVYNNGEGLIDGVHTDYIVPNLF
What is the function of this protein?
May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.
What are the official names of this protein?
Inter-alpha-trypsin inhibitor heavy chain H3, ITI heavy chain H3, ITI-HC3, Inter-alpha-inhibitor heavy chain 3.
What is the protein family that this protein belongs to?
Belongs to the ITIH family.
What are the subcellular locations of this protein?
Secreted.
Protein: HBA_PERCA
Sequence: VLSADDKANVKAAWGKLGGHGAEYGAEALGRMFCSFPTTKTYFPHFDVSHGSAQVKGHGAKVADALTTAAGHLDDLPGALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHHPAEFTPAVHASLDKFLASVSTVLTSKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: HHY1_YEAST
Sequence: MSLSFLLFSPFLPPCFSSISICLSVLSTVSFFFAFTIPHYVLRCGSVDEWHIHSSAEDFRTQRCVCAVKLSASLLGCLLACASWSLLLEVSRIKWHVGTAYS
What is the function of this protein?
Involved in vacuolar trafficking.
What are the official names of this protein?
Hypersensitivity to hygromycin-B protein 1.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PNP_PROM5
Sequence: MEGKNTSITFDGREIRLTTGLYAPQANGAVMIECGDTSLLVTATKTNKKEAADFLPLICDYEEKLYAAGRIPGGFMRREGRPPERATLIARLIDRPMRPLFPIWMRDEIQIVASCLSLDERVPADVLAVTGASLATLLGEIPFYGPMAAVRVGLLGDDFILNPSYREIEKGDLDIIVAGSPEGIVMIEAGANQLSEQDTIEAIDFGYEAVTELIKAQENLLKDLGIKQVKPSEPEVDNTLAAYLEKNCTKPIDLVLKKFDQSKEERDLELEKIKLEVHSKIDSLKDDNQLKVLTSENEKLIHSDFKKLTKKLMRSQIINDGKRVDGRDLDEVRKISAKAGILPKRVHGSAVFQRGLTQVLSTTTLGTPSDAQEMDDLNPSTEKTYLHHYNFPPYSVGETRPMRTPGRREIGHGALAERAIIPVLPGKETFPYVLRVVSEVLSSNGSTSMGSVCGSTLSLLDAGVPLKAPVSGTAMGLIKEGKEVRILTDIQGIEDFLGDMDFKVAGTEKGITALQMDMKITGLPVSIISDAIKKARPARLHILEKMQDAIDKPQESLSPHAPRLLSFRIDPELIGTVIGPGGRTIKGITERTNTKIDIEDGGIVTIASHDGAAAEEAQKIIEGLTRKVHEGEIFSGVVTRIIPIGAFVEILPGKEGMVHISQLSEARVERVEDVVRQGDEVTVRVREIDSRGRINLTLRGVAQNGGMSYPEPTPTPVAPLN
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7S_STAAT
Sequence: MTKETQSFEEMMQELEQIVQKLDNETVSLEESLDLYQRGMKLSAACDTTLKNAEKKVNDLIKEEAEDVKNDESTDE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.