PharMolix/UniProtQA huggingface dataset:
Protein: ATP8_BOMMO
Sequence: MPQMMPINWIFFLFFFICIFLIFNIMNYFIYEKKMHLINKFNQKKKLTFNWKW
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: RIMK_ECOHS
Sequence: MKIAILSRDGTLYSCKRLREAAIQRGHLVEILDPLSCYMNINPAASSIHYKGRKLPHFDAVIPRIGTAITFYGTAALRQFEMLGSYPLNESVAIARARDKLRSMQLLARQGIDLPVTGIAHSPDDTSDLIDMVGGAPLVVKLVEGTQGIGVVLAETRQAAESVIDAFRGLNAHILVQEYIKEAQGCDIRCLVVGDEVVAAIERRAKEGDFRSNLHRGGAASVASITPQEREIAIKAARTMALDVAGVDILRANRGPLVMEVNASPGLEGIEKTTGIDIAGKMIRWIERHATTEYCLKTGG
What is the function of this protein?
Is an L-glutamate ligase that catalyzes the ATP-dependent post-translational addition of glutamate residues to the C-terminus of ribosomal protein S6 (RpsF).  Is also able to catalyze the synthesis of poly-alpha-glutamate in vitro, via ATP hydrolysis from unprotected glutamate as substrate.  The number of glutamate residues added to either RpsF or to poly-alpha-glutamate changes with pH.
What are the official names of this protein?
Ribosomal protein S6--L-glutamate ligase, Poly-alpha-glutamate synthase, Ribosomal protein S6 modification protein.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: HPR_BACMK
Sequence: MKSGEKNYSVKEAMIFSQRIAQLSKALWKCVEKDWQQWIKPYDLNINEHHILSIAYHLKGASISEIAKFGVMHVSTAFNFSKKLEERGYLVFSKKEDDKRNTYIEITDKGEELLLRLMEEYDPENNSVFNGALELRNFYGKFPENIELIAILRNIYGQDFIDIFEKSLENIEENFTETDQKLVKK
What is the function of this protein?
Negative regulator of protease production and sporulation.
What are the official names of this protein?
HTH-type transcriptional regulator Hpr, Protease production regulatory protein Hpr.
Protein: CPCF_SYNP2
Sequence: MTVDVLIRAVNNPTSAQDLVKNVAQLAATKDEQAIPTLVEVLKFNNPGAAVAAVNGLINIGEAVVPYLLENVDGYNYGARAWMLRIFAGIGDPRALDLLIEAANKDFAFSVRRSAAKGLGNIQWHKVPDSEREVQQQKVCDCLFLALEDGEWVVRYGAIAGLEGLSQAIPEARKIVIKNKLTEFLTTEPEAAIRARIQKAILSLP
What is the function of this protein?
Required for the chromophorylation of the cpcA gene product.
What are the official names of this protein?
Phycocyanobilin lyase subunit beta, Phycocyanin operon protein CpcF.
What is the protein family that this protein belongs to?
Belongs to the CpcE/RpcE/PecE family.
Protein: RL7_CHICK
Sequence: MADKEAKKVPSVPESLLKRRQAYAAAKAKRLKRLLAQKKFRKAQRKIIYERAKAYHKEYRHMYRQEIRMARMARKAGNYYVPAEPKLAFVIRIRGINGVSPKVRKVLQLLRLRQIFNGTFVKLNKASINMLRIVEPYIAWGYPNLKSVHDLIYKRGYGKINKKRIALTDNSLIRKRLGKLGIICMEDVIHEIYTVGKNFKVVNNFLWPFKLSSPRGGMKKKTIHFVEGGDAGNREDQINRLIRRMN
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  Binds to G-rich structures in 28S rRNA and in mRNAs.  Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs.
What are the official names of this protein?
60S ribosomal protein L7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRF_CERS4
Sequence: MADDRLIVALDVPNVVQGLDLAERLGDAVSFYKIGLGMLTGGGLALANELKQERGKRIFLDMKLFDIGATVEAAVRGFASYDLDFLTVHGDPQVVRAAVQGASGSGLRILAVTVLTSLDRADLDANMIRAGDLAEITLERAARALDAGAHGVIASPQEAAAIRALPQAAGRLIVTPGVRPTGAALGDQKRVATPARAIADGADHIVVGRPIWQAGDPRAAALAVQAELPTRG
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: RL18_RHOPS
Sequence: MSKLNVTNARRKTRVRIALRRTANGRPRLSVFRSSKHIYAQVIDDLKGETLASASSLEKSLRDAGNTGANIDAAKAVGKLLAERAVQQGVKEVVFDRGGYLYHGRVKALADAARESGLSF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: LEPA_SYMTH
Sequence: MVDQRHIRNFCIIAHIDHGKSTLADRLIEFTGVLTKREMTDQVLDNMELERERGITIKAQSVRMDYVADDGEQYVLNLIDTPGHVDFTYEVSRALAACEGALLVVDASQGIEAQTLANVYMALEHDLEIIPVINKIDLPAADPEKVKKEIEEVIGLDTSIAILASAKTGIGMKEILEAVVNFVPPPKGDRRAPLRALIYDSFYDSYKGVITYFRIFEGTVRKGDRIRFMATGKEFIVDELYIFRPGLTPVEELTAGEVGALAATIREVKHVRVGDTITLADNPAAEPLPGYRKATPMVFTGLYPVETNDYGRLRDALEKLQLNDASLSFEPETSEALGFGFRCGFLGLLHMDVIQERLEREFDLNLITTAPNVVYRVNMTSGEQIMIENPANWPDPSKIESVEEPVVRASIITPTEYVGPLMELCQDRRGTFLNMEYLNEKRVNLHYKLPLAEIMYDFFDQLKTRSRGYASFDYEVTGYEPSDMVKMDILVHGQPVDALSCIVHREKAQKLGRALVQKLRKLIPRHLFEVPIQAAVGNKILARENIAPLRKDVLAKCYGGDVTRKRKLLEKQKEGKKRMKAVGSVEIPQEAFMAVLSTDPDED
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: UPP_SHEB9
Sequence: MKVVEVKHPLVRHKIGLMREGDISTKRFRELAAEVGSLLTYEATADFETETVTIEGWNGPVEVDQIKGKKVTVVPILRAGLGMMDGVLEHIPSARISVVGIYRDEETLEPVPYFEKLASDMNERIALVVDPMLATGGSMIATVDLLKKRGCTSIKALVLVAAPEGIKALEAAHPDIELYTAAIDKCLNEKGYILPGLGDAGDKIFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: Y1062_METJA
Sequence: MKIAIITDGSVEMGMGHVYRTLSLANELRKFNVNEIIFFTKSDEDVIKKIEENGFKVIKCSDNNDILKNIKNIKPDVVIIDDLGIEEDFAKNIRELCKKLIFFDNPNPSSNKYADIVVNAIVGSELKNRKYFDEENKTLYFYGPKYLILRNEFYKVKKEMLSRSKNKETKNILIAFGGSDPSNLTCKVLEELLSKDRDFNINVVLGPKFQYEDELNNLLKRYSKSDKIKIYKNIDNMAELMKDNDLIITSPGMTMFEALFLGIPVVVLYQNELQRECYDDYLKKISKTHLNPLKEGYFIDAEHTDLHIGKGKFEIIEAITNIYNCKKIGEDSKIIIRQITDNDLELLMAWRSNPLIYKFFYIQKEPLKWEEHYSWWMSRENRVDWIILLRENNTIRKVGSVNVSQLNTDNPEIGILIGEFFLWGKHIGRHSVSLVLKWLKNIGYKKAHARILENNIRSIKLFESLGFKKTKKGRENEWIYEVNL
What are the official names of this protein?
Uncharacterized protein MJ1062.
Protein: RSMG_CYTH3
Sequence: MQIIEKYFKHLSPEQVKQFGALHSLYTEWNEKINVVSRKDIDQLYERHVLHSLGIAKVMAFKPGTRILDVGTGGGFPGIPLSILFPESDFHLIDSIGKKIKVVEEVSAGAGIKNIRTTHGRAEDVTDRYHFVVSRAVTRFKPFWGWVAKKFSDEQFNDLNNGILYLKGGDLDEEIQELNRPAYEYDLNMFFEEEFFDTKKVVHVPAF
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2077_MYCTO
Sequence: MLATLSQIRAWSTEHLIDAAGYWTETADRWEDVFLQMRNQAHAIAWNGAGGDGLRQRTRADFSTVSGIADQLRRAATIARNGAGTIDAAQRRVMYAVEDAQDAGFNVGEDLSVTDTKTTQPAAVQAARLAQAQALAGDIRLRVGQLVAAENEVSGQLAATTGDVGNVRFAGAPVVAHSAVQLVDFFKQDGPTPPPPGAPHPSGGADGPYSDPITSMMLPPAGTEAPVSDATKRWVDNMVNELAARPPDDPIAVEARRLAFQALHRPCNSAEWTAAVAGFAGSSAGVVGTALAIPAGPADWALLGAALLGVGGSGAAVVNCATK
What are the official names of this protein?
Uncharacterized protein MT2137.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NECT4_HUMAN
Sequence: MPLSLGAEMWGPEAWLLLLLLLASFTGRCPAGELETSDVVTVVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRLDGPLPSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSGKQVDLVSASVVVVGVIAALLFCLLVVVVVLMSRYHRRKAQQMTQKYEEELTLTRENSIRRLHSHHTDPRSQPEESVGLRAEGHPDSLKDNSSCSVMSEEPEGRSYSTLTTVREIETQTELLSPGSGRAEEEEDQDEGIKQAMNHFVQENGTLRAKPTGNGIYINGRGHLV
What is the function of this protein?
(Microbial infection) Acts as a receptor for measles virus.
What are the official names of this protein?
Nectin-4, Ig superfamily receptor LNIR, Nectin cell adhesion molecule 4, Poliovirus receptor-related protein 4.
What is the protein family that this protein belongs to?
Belongs to the nectin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell junction, adherens junction. Note=Colocalizes with AFDN at cadherin- based adherens junctions (PubMed:11544254). SUBCELLULAR LOCATION: [Processed poliovirus receptor-related protein 4]: Secreted. Note=The secreted form is found in breast tumor patients (PubMed:15784625).
Protein: ASPA_PROM9
Sequence: MTVQRILIVAGTHGNEINPIWAVKQFNRNENSLKHGIEYEYIIGNPIAYEKGCRYIDADLNRSFKKSKNYDQNENSFYEISRANFLVDQFGINGSKPCQIAIDLHTTTANMGTSIVMYGRRFKDFCLAALLQNKFGLPIYLHEKDKSQTGFLVEAWPCGLVIEIGAVAQNFYDPKIINRFLIIISSLRDEIDKLKKNLIELPKDLVVHVHQGSVDYPRDEKGDIDGLIHPKRINRDWKMIKKGDPLFLNSQGIIYKYDGDQFIWPVFIGEVAYKEKQIAMSYTNKEVICSKNEWVQEFHRL
What are the official names of this protein?
Probable aspartoacylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Aspartoacylase subfamily.
Protein: Y3463_PSEAE
Sequence: MLIPHDLLEADTLNNLLEDFVTREGTDNGDETPLDVRVERARHALRRGEAVILFDPESQQCQLMLRSEVPAELLRD
What are the official names of this protein?
UPF0270 protein PA3463.
What is the protein family that this protein belongs to?
Belongs to the UPF0270 family.
Protein: PYRB_NOVAD
Sequence: MQSQNTPAAGRYPAGGLAFPHRDLTGIGQLARHEILYLLDEAEQWVELNRQSQKTTDLLNGLTIINAFFENSTRTLLSFEIAGKRLGADVVNMHAATSSVKKGETLIDTAMTLNAMRADAIVIRHASSGAVRLIAEKVDCPVLNAGDGQHEHPTQALLDALTMRHAMKLPAGSDLNGLKVTICGDILHSRVARSNILSLTALGAEVRVCAPPALMPAEIEAMGVTPFHDFDAALKGANIVMMLRLQQERMSGQFIPSPREYRHLYGLTPERLARAEADAFVMHPGPMNRGIEIDSTVADHPTRSLITRQVEMGVAIRMACLEVLTRRARRTPGWEAEGASA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: Y942_STAAC
Sequence: MNPIVEFCLSNMAKGGDYVFNQLENDPDVDVLEYGCLTHCGICSAGLYALVNGDIVEGDSPEELLQNIYAHIKETWIF
What are the official names of this protein?
UPF0349 protein SACOL0942.
What is the protein family that this protein belongs to?
Belongs to the UPF0349 family.
Protein: PDXA_GLOC7
Sequence: MKSLALTLGDPAGIGSEVILKALADPSVGENYNITVVGSRSLLEESYHQLRSLPHVNHSDLVDPANLLILDIPLDKTTKSQIQLGKGNAASGEASFTYLQAAIAGTLKGEFAGIVTAPIAKSCWKAAGYHYPGQTEVLAQAAGVEKFGMLFVARSPYTGWMLRTLLATTHIPLSQVPTVLTPELMTLKLELLIDCLKNDFRLDHPKIAIAGLNPHSGEQGQLGTEERDWLTPWLEEEKKRHCEVELVGLVPPDTMWVTPGQAWYGNAPHPQHGADGYLALYHDQGLIPVKLMAFDQAINTTIGLPFIRTSPDHGTAFDIAGKGIARPASMIEAIKLAQALVNG
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FETP_VIBC3
Sequence: MARTVFCTRLQKEADGLDFQLYPGELGKRIFDNICKEAWAQWQTKQTMLINEKKLNMMDPEHRKLLEQEMVNFLFEGKEVHIEGYTPPAK
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: RL9_SERP5
Sequence: MQVILLDKVANLGSLGDQVNVKAGYARNFLVPQGKAVPATKKNVEFFEVRRAELEAKLAEILTAAEARATKINELGSVTIASKSGDEGKLFGSIGTRDIADAVTAAGVEVAKSEVRLPNGVLRTTGEHEVQFQVHSDVFAQLNVVVVAEA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: VATE_CLOB6
Sequence: MSNLENLTSKIIEDANKEAEKLLSEAKKEENKIVDEKIKKANKAKEQIIERAKRESRTKAERVISNAHLKVRNNKLEAKQEMINKVFDKAVIKLQNLSKDEYLNFVKSSILSLDIEGDEEIIVSPNDKDKIDISLMLTLNNQLKAKGKKALLKISNENRNIKGGFILYKNGIEINNSFEALVDSLRDELEQEIIEALFS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type proton ATPase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: HIS7_ECOL6
Sequence: MSQKYLFIDRDGTLISEPPSDFQVDRFDKLAFEPGVIPELLRLQKAGYKLVMITNQDGLGTQSFPQADFDGPHNLMMQIFTSQGVQFDEVLICPHLPADECDCRKPKVKLVERYLAEQAMDRANSYVIGDRATDIQLAENMGINGLRYDREILNWPMIGEQLTKRDRYAHVVRNTKETQIDVQVWLDREGGSKINTGVGFFDHMLDQIATHGGFRMEINVKGDLYIDDHHTVEDTGLALGEALKIALGDKRGICRFGFVLPMDECLARCALDISGRPHLEYKAEFTYQRVGDLSTEMIEHFFRSLSYTMGVTLHLKTKGKNDHHRVESLFKAFGRTLRQAIRVEGDTLPSSKGVL
What are the official names of this protein?
Histidine biosynthesis bifunctional protein HisB.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_HELPH
Sequence: MTLGIDEAGRGCLAGSLFVAGVACSEKTALEFLKMGLKDSKKLSQKKRFFLEDKIKTHGEVGFFVVKKSAEAIDSLGLGACLKLAIEEILENGCSLANEIKIDGNTAFGLNKRYPNIQTIIKGDETIAQIAMASVLAKAAKDREMLELHALFKEYGWDKNCGYGTKQHIEAIIKLGATPFHRHSFTLKNRILNPKLLEVEQRLV
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM175_MOUSE
Sequence: MSRLQTEEQAVDSEGDSSLHRRNEEGTQSSHRMLGFSDALLSIIATVMILPVTHTEISPEQQFDKSIQKLLATRIAVYLMTFLIVTVAWTAHTRLFQVVGKIDDTLALLNLACMMTITLLPYTFSLMVTFPDVPLGIFLFCVCVIAIGSVQAMIVGYAFHFPHLLNPQIQCSTHRDLSRRHILHLVLRGPALCFVAAVFSLFFFPLSYLLMVTVIFLPHISKATTWCKDKLMGQRESPAHDMEPFSIDLHAPLSKERVEAFSDGVYAIVATLLILDICEDNVPDPKDVQEKFSGSLVAALGAYGPQFLAYFGSFATVGLLWFAHHSLFLHVRKATQTMGLLNILSLAFVGGLPLAYQQTSAFARQPHDELERVRVSCAIIFFASIFQFAIWTTALLHQTETLQPAVQFGGQEHAFMFAKLALYPCASLLAFAATCLLSRFSTAIFHLMQISVPFAFLLLRLLVRLALAGLQVLRGLWPHHPQQDQSEPEAQSQLLPDPC
What is the function of this protein?
Proton-activated proton channel that catalyzes proton efflux from endosomes and lysosomes to maintain a steady-state pH (PubMed:35750034).  Activated at low pH (under pH 4. 6) by luminal side protons: selectively mediates lysosomal proton release from lysosomes, eliciting a proton leak that balances V-ATPase activity to maintain pH homeostasis (By similarity).  Regulation of lumenal pH stability is required for autophagosome-lysosome fusion (PubMed:26317472).  May also act as a potassium channel at higher pH, regulating potassium conductance in endosomes and lysosomes (PubMed:26317472, PubMed:33505021).  The potassium channel activity is however unclear as it was tested in non-physiological conditions for a lysosomal channel (By similarity).  Constitutes the pore-forming subunit of the lysoK(GF) complex, a complex activated by extracellular growth factors (PubMed:33505021).  The lysoK(GF) complex is composed of TMEM175 and AKT (AKT1, AKT2 or AKT3), a major target of growth factor receptors: in the complex, TMEM175 channel is opened by conformational changes by AKT, leading to its activation (PubMed:33505021).  The lysoK(GF) complex is required to protect neurons against stress-induced damage (PubMed:33505021).
What are the official names of this protein?
Endosomal/lysosomal proton channel TMEM175, Transmembrane protein 175, mTMEM175.
What is the protein family that this protein belongs to?
Belongs to the TMEM175 family.
What are the subcellular locations of this protein?
Endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein.
Protein: ATPE_RIPO1
Sequence: MALQVRVITPDKIVWDGDVEEAILPSTSGQLGILPSHAPLLTNLDIGVMRVRLDKDWKSLVVMGGIAEVEQDILQVLVNSAEIGDDITKEDAQADFSEAQSRLEEANKGSDRREQIKASQAYKRARARLQAAGGLV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: PER4_CAPAN
Sequence: EMVALSGSHTIGQAR
What is the function of this protein?
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.  These functions might be dependent on each isozyme/isoform in each plant tissue.
What are the official names of this protein?
Peroxidase 4.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TRPF_SULNB
Sequence: MRVKICGITNLRDALHAVECGADALGFVFYNESPRYITPKDAKRIIDQLPPFVERVGLFVNEGVETIDTVCRYSDISLAQIHFDVDEESLDAISLKTLPVVRARTAEDVHRFPDRYRLVDAYCEAYGGSGKRLNLEWFDGVDCSRIILAGGLTPDNVNEVKQYGFYGVDVSSGVESVKGKKDLQKVERFLRNAKSL
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: MYO5A_MOUSE
Sequence: MAASELYTKFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYRLDPKTGELPHLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADSFHYTKQGGSPMIEGVDDAKEMAHTRQACTLLGISESYQMGIFRILAGILHLGNVGFASRDSDSCTIPPKHEPLTIFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDHVNQALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKPRMSNKAFIIKHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAISPTSATSSGRTPLTRVPVKPTKGRPGQTAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLGDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKRYLCMQRAAITVQRYVRGYQARCYAKFLRRTKAATTIQKYWRMYVVRRRYKIRRAATIVIQSYLRGYLTRNRYRKILREYKAVIIQKRVRGWLARTHYKRTMKAIVYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLMEKLTNLEGVYNSETEKLRNDVERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKSIEERADKYKQETDQLVSNLKEENTLLKQEKETLNHRIVEQAKEMTETMERKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMLNVPKPGHKRTDSTHSSNESEYTFSSEFAETEDIAPRTEEPIEKKVPLDMSLFLKLQKRVTELEQEKQLMQDELDRKEEQVFRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLYFEELYADDPKKYQSYRISLYKRMIDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQGMLEYKREDEQKLVKNLILELKPRGVAVNLIPGLPAYILFMCVRHADYLNDDQKVRSLLTSTINSIKKVLKKRGDDFETVSFWLSNTCRFLHCLKQYSGEEGFMKHNTSRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVRVLENILQPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIADEGTYTLDSILRQLNSFHSVMCQHGMDPELIKQVVKQMFYIVGAITLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSGAKETLEPLIQAAQLLQVKKKTDDDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVSVSFIRTIQMRLRDRKDSPQLLMDAKHIFPVTFPFNPSSLALETIQIPASLGLGFIARV
What is the function of this protein?
Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament.  Involved in melanosome transport.  Also mediates the transport of vesicles to the plasma membrane.  May also be required for some polarization process involved in dendrite formation.
What are the official names of this protein?
Unconventional myosin-Va, Dilute myosin heavy chain, non-muscle.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
Protein: RL18E_METPE
Sequence: MTGRVKKTNPRLTSLITTLKDASRTGEVKIWRDIANRLEASTSAHAEVNISKINRYAAEGETILVPGKVLGSGMLNQSVRVAALNFSESAVSKIAKAQGTCMTIEELLANNPKGSRVRILR
What are the official names of this protein?
50S ribosomal protein L18e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL18 family.
Protein: ZN692_RAT
Sequence: MASPVADASRRRREKRRQLDARRSKCRIRLGGHMEQWCLLKERLGFSLHSQLAKFLLDRYTSSGCVLCAGPEPVPQKGLQYLVLLSHTHSRECSLVPGLRGPGGGEGELVWECSAGHTFSWEPSLIPTPSEVPKQAPLTHTTERTWCSEARRKQEAEGLECEHRERTQETRLSRRVEPPLETDPSVGEDQVVEEEEEEEEEEEEEELLSDASPWTYSSSPDDSEPDVPRPPPSPVTHTPKEGEIPPVPATLPTPCAVLASLGSTAALTSDTEVQMELSRTSQVPAELQMTESLDSPGSQAQSAPNPTCDEDTAQIGLRRIRKAAKRELMPCDFPGCGRIFSNRQYLNHHKKYQHIHQKSFCCPEPACGKSFNFKKHLKEHVKLHSDARDYICEFCARSFRTSSNLVIHRRIHTGEKPLQCEICGFTCRQKASLNWHRRKHAETAAALRFPCEFCGKRFEKPDSVVAHCSKSHPALLPVQESPGSLGSSPSISAPEPLQSPEGTSFSTSYDSNPAPSTSISSPGVPAPRNTEKS
What is the function of this protein?
May act as an transcriptional repressor for PCK1 gene expression, in turns may participate in the hepatic gluconeogenesis regulation through the activated AMPK signaling pathway.
What are the official names of this protein?
Zinc finger protein 692, AICAR responsive element binding protein.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.