PharMolix/UniProtQA huggingface dataset:
Protein: ARNC_PSEA8
Sequence: MKPYPIDLVSVVIPVYNEEASLPELLRRTEAACLELGRAFEIVLVDDGSRDRSAELLQAAAERDGSAVVAVILNRNYGQHAAILAGFEQSRGDLVITLDADLQNPPEEIPRLVERAAQGYDVVGSIRAERQDSAWRRWPSRLVNLAVQRSTGVAMHDYGCMLRAYRRSIVEAMLACRERSTFIPILANGFARHTCEIRVAHAERAHGESKYSAMRLLNLMFDLVTCMTTTPLRLLSLVGGGMALAGFLFALFLLVLRLAFGAAWAGNGLFVLFAVLFMFSGVQLLGMGLLGEYLGRMYSDVRARPRFFIERVVRATPSALPSALQRAGFTSSSSEPSTP
What is the function of this protein?
Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase, Undecaprenyl-phosphate Ara4FN transferase, Ara4FN transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CD44_CRIGR
Sequence: MDKFWWHAAWGLCLLPLSLAHEQIDLNITCRYAGVFHVEKNGRYSISRTEAADLCQAFNSTLPTMDQMVMALSKGFETCRYGFIEGHVVIPRIQPNAICAANHTGVYILTSNTSHYDTYCFNASAPLEEDCTSVTDLPNSFEGPVTITIVNRDGTRYSKKGEYRTHQEDIDASNTTDDDVSSGSSSEKSTSGGYVFHTYLPTIHSTADQDDPYFIGSTMATRDQDSSMDPRGNSLTVTDGSKLTEHSSGNQDSGLNSTSRPGGKPRVPEWLIVLASLLALALILAVCIAVNSRRRCGQKKKLVINSGNGKVEDRKPSELNGEASKSQEMVHLVNKEPSETPDQFMTADETRNLQNVDMKIGV
What is the function of this protein?
Cell-surface receptor that plays a role in cell-cell interactions, as well as cell adhesion and migration, helping them to sense and respond to changes in the tissue microenvironment.  Participates thereby in a wide variety of cellular functions including the activation, recirculation and homing of T-lymphocytes, hematopoiesis, inflammation and response to bacterial infection.  Engages, through its ectodomain, extracellular matrix components such as hyaluronan/HA, collagen, growth factors, cytokines or proteases and serves as a platform for signal transduction by assembling, via its cytoplasmic domain, protein complexes containing receptor kinases and membrane proteases.  Such effectors include PKN2, the RhoGTPases RAC1 and RHOA, Rho-kinases and phospholipase C that coordinate signaling pathways promoting calcium mobilization and actin-mediated cytoskeleton reorganization essential for cell migration and adhesion.
What are the official names of this protein?
CD44 antigen, Extracellular matrix receptor III, ECMR-III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Hermes antigen, Hyaluronate receptor, Phagocytic glycoprotein 1, PGP-1, Phagocytic glycoprotein I, PGP-I.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell projection, microvillus. Note=Colocalizes with actin in membrane protrusions at wounding edges. Co-localizes with RDX, EZR and MSN in microvilli.
Protein: SRSA_DICDI
Sequence: MIAKVFKSITPESYILLVNAGLISAYGVRIIFQSVKNDEGKVDEKAHIGIGHFFKKRGAQLVDGKNLTDILKEKKKKKKKKKKINISNKLIIFKISRQLYSKLKLK
What is the function of this protein?
Involved in starvation response and aggregation stage of the life cycle.  May be involved in fruiting body morphogenesis and spore formation.
What are the official names of this protein?
Starvation responsive small protein A.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PDLI3_RAT
Sequence: MPQNVVLPGPAPWGFRLSGGIDFNQPLVITRITPGSKAEAANLCPGDVILAIDGFGTESMTHADAQDRIKAASYQLCLKIDRAETRLCPAVSEDGKAHPFKINLEAEPQDVNYFEHKHNIRPKPFIIPGRTSGCSTPSGIDCGSGRSTPSSVSTVSTICPGDLKVAAKMAPNIPLEMELPGVKIVHAQFNTPMQLYSDDNIMETLQGQVSTALGETPSMSEPTASVPPQSDVYRMLHDNRDEPAAPRQSGSFRVLQELVNDGSDDRPAGTRSVRPVTKVHGGAGGAQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFVEGELYCEMHARARTRPPEGYDTVTLYPKA
What is the function of this protein?
May play a role in the organization of actin filament arrays within muscle cells.
What are the official names of this protein?
PDZ and LIM domain protein 3, Actinin-associated LIM protein, Alpha-actinin-2-associated LIM protein, SK-2.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere, Z line. Note=Localizes to myofiber Z-lines.
Protein: KXD1_YEASV
Sequence: MVTGISEENDDEETFSAVHSSTPSINSQSYAIPITEEMSSSFHDSISTTSNSSGSFDSDGSNVSDVVEQNEMDNESNVDEDLFLDNDIPQSSNLLPTDAQDPGPIFDVSRYIFDSLKQSIDSADFSEALSLQTKTSAVINSKSLELKQYIDEMKSRLTQLQEKFENGEATSKKIKRDLETSRKNIDYLNAALRVDFPIEFNQAREKILERRLNEDHDC
What is the function of this protein?
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.
What are the official names of this protein?
Biogenesis of lysosome-related organelles complex 1 subunit KXD1, BLOC-1 subunit KXD1, KxDL homolog.
What is the protein family that this protein belongs to?
Belongs to the KXD1 family.
What are the subcellular locations of this protein?
Endosome.
Protein: RL11_BRASB
Sequence: MAKKVTGYLKLQVPAGAANPSPPIGPALGQRGLNIMEFCKAFNAQTQKEEKNTPIPVVITIYADRSFTFEMKTPPMSYFLKQAAKIQSGSKAPGRDKAGKVTKAQVREIAEKKMKDLNCDSIESAMKMVEGSARSMGLEVAG
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: PSAB_ORYSJ
Sequence: MELRFPRFSQGLAQDPTTRRIWFGIATAHDFESHDDITEERLYQNIFASHFGQLAIIFLWTSGNLFHVAWQGNFESWIQDPLHVRPIAHAIWDPHFGQPAVEAFTRGGAAGPVNIAYSGVYQWWYTIGLRTNEDLYTGALFLLFLSTLSLIGGWLHLQPKWKPSLSWFKNAESRLNHHLSGLFGVSSLAWTGHLVHVAIPASRGEYVRWNNFLDVLPYPQGLGPLLTGQWNLYAQNPDSSNHLFGTTQGAGTAILTLLGGFHPQTQSLWLTDIAHHHLAIAFIFLIAGHMYRTNFGIGHSIKDLLEAHTPPGGRLGRGHKGLYDTINNSIHFQLGLALASLGVITSLVAQHMYSLPSYAFIAQDFTTQAALYTHHQYIAGFIMTGAFAHGAIFFIRDYNPEQNEDNVLARMLDHKEAIISHLSWASLFLGFHTLGLYVHNDVMLAFGTPEKQILIEPIFAQWIQSAHGKTTYGFDILLSSTSGPAFNAGRTLWLPGWLNAVNENSNSLFLTIGPGDFLVHHAIALGLHTTTLILVKGALDARGSKLMPDKKDFGYSFPCDGPGRGGTCDISAWDAFYLAVFWMLNTIGWVTFYWHWKHITLWQGNVSQFNESSTYLMGWLRDYLWLNSSQLINGYNPFGMNSLSVWAWMFLFGHLVWATGFMFLISWRGYWQELIETLAWAHERTPLANLIRWRDKPVALSIVQARLVGLAHFSVGYIFTYAAFLIASTSGKFG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2, PSI-B, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ARND_SODGM
Sequence: MKNVGLRIDVDTWRGTRDGMPRLLELLAAQQIQATFFFSVGPDNMGRHLWRLAKPQFLLKMLRSRAASLYGWDILLAGTAWPGRKIGQGLAAQIRAAAADHEVGLHAWDHFAWQTWAGVWSERQLTEQIRLARDALTAIIERPVTCSAVAGWRADDRVVQAKQPFDFHYNSDCRGTEPFRPLLANGAFGAVQIPVTQPTFDEAIGQTTTRAGYNHFILDSIKADRGTPVYTIHAEVEGIALSGMFQELLSMAVAEGIRFCPLRELLPQDTAALPVGQVVRGEIPGREGWVGCQRLLK
What is the function of this protein?
Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
Protein: P7_RDVF
Sequence: MSAIVGLCLLSEKVVLSRSLTDEVSKLYKLNRGNVKEPRKYATERMSTQSKPVALQVPVSTIILDYKDEDFIKQNPTYSAMDIIGSPSNTAPQTAFQSIMPSLSALFNTPFIQGAFRHRVISSMGPEISYLVMVIGPPSGFMDTPMYRTVNHLSILMSNADVDLIDIIAINSTMAKSTKLVFASTFQAMLVNDVYDRCMVLVGIFLSQALPFFRNYVNVQSKGSLPPAVAACLNTPIKELFSMGSGKREPLALEFRKDNEGQCLGIVLPKGHEGDTLSSRYPAVFINESEPFSDEERSELSKLKRTDPDAYEKLYSETISKHVSDGSYGNRVIISHKMSRLSNGGVKIIGRFKISDFNTVKKNLSSRPGEVDSAKEQWEALSGNGLVTDNNTSMLHDKILDTITSNKPGVVLRDGNKKSDNIVVCFKNGFPNKKHSLLQLTKNGISVVSLDELTDAGILVESTGPDRVRRSPKALANKLSSFKGRKVTLDVDNMSTEALIQKLSTL
What is the function of this protein?
Probable component of the transcriptional machinery present in the inner capsid.  Displays dsRNA binding activity and may play an important role in the sorting of viral RNA and virion assembly.  Together with the RNA-directed RNA polymerase P1 and capping enzyme P5, forms an transcriptional complex positioned near the channels situated at each of the five-fold vertices of the core (By similarity).
What are the official names of this protein?
Protein P7, 55 kDa core protein.
What is the protein family that this protein belongs to?
Belongs to the phytoreovirus protein P7 family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=Located inside the inner capsid (By similarity). Found in the interior of spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: TFNPH_ASFP4
Sequence: MSCVHNNTSFPVQTEAYLKEVFEKYKELQESKDTSLTARFARALKYYQFLIYTAFSDPKFGIGQGENTRGLLIYHQMGMGKTILSLSLAISLSHIYNPILIAPKSLHSNFQQSLLKLIKLLYPETTDHSKELQKISRRFRFVSLDAYNMGQQIIKAGGSLNGCLLIVDEAHNLFRGIINSANDKTNARQLYNNIMQAKNIRILFLTGTPCSKDPFEMVPCFNMLSGRILLPLHYERFYTAYVNKTTNSPLNADKLLNRLVGMISYAGNQNELNKLFPTELPLIIEKVEMSPEQYRQYLLARDVENAEKHASSGMYEKINAAALCLPGSEQESGSSYYVRSRMISIFASEMLTVKEDEKLSEAVQQLPKEAFTENSSPKIVCMLKNIKTSPGPVLIYSQFVELGLHVVARFLEIEGYQCLQPLKVLEEGHNTILLHKDGKDLMVKNFAEDGPTHTLVLSSKITRFTLITGKILSKERDMIQQLWNSPLNIHGEVIKILLVSKTGAEGLDLKYGRQVHILEPYWDKAREDQVKARIIRIGSHDALPPEEKTVQPFLYIAVANQKMFYSIPEGSQEQKTIDERFHERGLEKSHLNSAFRDLLKRAAIECAFNGESGCLMCQPTNALLFHENFERDLRLPNPCQPLVKAEVKAYSISYEGKQFFYQKNKDVGLGYTFYEYNPIIKAYIEIKPSNPLYIKLIKHVQAGTTA
What is the function of this protein?
Putative DNA-dependent ATPase required for providing the needed energy to achieve the termination of early transcripts.
What are the official names of this protein?
Termination factor NPH-I homolog.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
What are the subcellular locations of this protein?
Virion. Note=Found in association with viral nucleoid.
Protein: Y205_HAEIN
Sequence: MKISFHSVLIGLASFIGVQQGVIANPSSHQSISTESAEALKQQFSMALAKQDKQQITNLQKKLTALFSLPPQFLDNQIQISEKILTRIFKTDKNLTPKFLDYLYFEPINTVDANLIQEMKKNLLVSFLANDQAKIYIRQTDNSEQFVQTLMERGAKADQIILLSLNAKGIFQKIIEQIRQDFPNQTIFSITENRISLITPSSEIKSRLALANMMFNRQFKGVEVDDFSYLDQPRENLQHNNDAIRYKTFQAMLEGLN
What are the official names of this protein?
Uncharacterized protein HI_0205.
Protein: KAT2B_DANRE
Sequence: MSESTGIPQGSPAVGAAGSAPAAPGVGGTECSGAAVGSARIAVKKAQLRSSPRPKKLEKLGVYSSCKAEGACKCNGWKSQNPPPTPPPPTPPRAEQPTAVSLMEPCRSCSHALGDHVTHLENVSEEEMNRLLGIVLDVEYLYTCVHKEEDPDTKQVYFSLFKLLRKCILQMGRPVVEALESPPFEKPSIEQGVNNFVQYKFSHLPSKERQTIVELAKMFLNQINYWQLETPSQKRQRAPDDDVAGYKVNYTRWLCYCNVPQFCDSLPRYEATQIFGRIFLRSVFTIMRKQLLEQARQEKDKLPPEKRTLILTHFPKFLSMLEEEVYSHNSPIWSENFMIGLSGGQIPTVVSAPPVNRSLYYSSSPAPVELAGGGSVSPARKTASVLEPNPGGEKRKPAEPLSHEDSKRPRVVGDIPMELINEVMSTITDPTAMLGPETSLLSAHSARDEAARLEERRGVIEFHVIGNSLNQKPNKKILMWLVGLQNVFSHQLPRMPKEYITRLVFDPKHKTLSLIKDGRVIGGICFRMFPTQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKHEILNFLTYADEYAIGYFKKQGFSKDIKVPKSKYVGYIKDYEGATLMGCELNPCIPYTEFSVIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKEGVRQIAIESIPGIRETGWKPLGKSKELKDPDQLYSTLKNILTQVKSHPNAWPFMEPVKKNEAPGYYQVIRFPMDLKTMSERLKSRYYTTRKLFMADMQRIFTNCREYNPPESEYYKCANLLEKFFYTKIKEAGLIDK
What is the function of this protein?
Functions as a histone acetyltransferase (HAT) to promote transcriptional activation (By similarity).  Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles (By similarity).  Also acetylates non-histone proteins (PubMed:29174768).  Involved in heart and limb development by mediating acetylation of tbx5 (PubMed:29174768).  Also acetylates spermidine (By similarity).  Together with kat2a, required for growth and differentiation of craniofacial cartilage and bone by regulating acetylation of histone H3 at 'Lys-9' (H3K9ac) (PubMed:30424580).
What are the official names of this protein?
Histone acetyltransferase KAT2B, Histone acetyltransferase PCAF, Histone acetylase PCAF, Lysine acetyltransferase 2B, P300/CBP-associated factor, P/CAF, Spermidine acetyltransferase KAT2B.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. GCN5 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Mainly localizes to the nucleus. Also localizes to centrosomes in late G1 and around the G1/S transition, coinciding with the onset of centriole formation.
Protein: DNLJ_BRADU
Sequence: MMARAAKSKPLRDVAELTKAQAKVELMRLALELEGHDKRYYQDDAPTVTDAEYDALRQRFNAIEKRFPEFVSAESPSQKVGAAPSGRFRKVRHAVPMLSLDNAFAEEDVRDFVGRIVRFLKLDDDKIDFSAEPKIDGLSMSLRYEGGELVTAATRGDGAEGEDVTANIRTLEDVPQKLKGRNVPDICEVRGEVYMTKKAFLALNERQKAAGDTIFANPRNSAAGSLRQKDPTITASRPLGFFAYAWGEMSAMPEETQTGMIHWFERCGFKTNPLTRLCHSVEELIAFHQRIEEERAELDYDIDGVVYKVDRIDWQERLGFVSRTPRWGIAHKFPAEQAMTVLRDIEIQVGRTGSFTPVGKLEPVGVGGVIVQNVTLHNEDYIKGIGNKGEVLREGRDIRIGDTVVIQRAGDVIPQVVDVVLDKRPKTAKEFHFPKTCPCPLHTDVTREETAAGEEGSRARCTGEFACPYQKIEHLKLFVSRRAFDIDGLGEKQLQYFFDEGFVKEPADIFTLEKRNAKLKLEEIEGYGATSVRNLFAAIESRRRIALERFVYALGMRHVGETTALALARGYGSWEAFHDACLKVAKGDEEAMADMDALDQIGDTVIKSIADYFGESHNRGIVERLTKEVEIVDAEKPKSNSAVAGKTVVFTGSLEKMTRDEAKATAERLGAKVSGSVSKKTDLVVAGPGAGSKLAEANKHGVKVLTEDEWLKLIGE
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: CARB_THEAC
Sequence: MPRRDDIHRILVIGSGPVVIGQAAEFDYSGSQACLSLREEGYYVVLLNSNPATIQTDHRIADRVYIEPITVEAVERIIEKEKIDAIEPHMGGQTALNLAVKLKNSGILQRYGIKIIGTPVESIELAEDREKFYEFLKAMGEPQPARYRIRRDHIDEDVASIPDIPVIVRTSFSLGGTGGSIVQNRQDLLAMAENLFRASDIDYLEVNESLEGMKEIEYEVIRDSFGNCITVCNMENLDPMGVHTGESIVVTPSQTLSDIEYQMLRDSAIRIISGLGIEGACNIQFALSEGRYYVIEVNPRTSRSSALASKATGYPIARIAAKIAAGYGLHEIKNPITKSTFAAYEPSLDYVTVKIPRWPFDKFSVDRTIGVQMKSIGEVMGIGRTFEEALMKAIASLDNAFSSNIRLHVPDDELWRLIGKPNDRRIFAIFEGLFRNFDVKRMSRLSGYDEYFIEKMRNIVEALRNMDMGRIPENLLRIKRIGIPDEIISAFCGVPADTITKYRIDRNIMPVYKRIDTCSGEFEVAVPYMYSTYEDEDETPDLSGSIMIIGSGPNRIAQGLEFDYGSVKAILALRDMGYRSIMLNSNPETVSTDFDISDALFFEPVTPEYVVNVIRRSGCAGLIVQFSGQTGQNMARRIEEILGKHIVLGTSTESIDRIEDRTVFSRVIEGLGIKQPPFAIAENENDTVRKAMGLGLPIILRSSHVIGGRSMEIIYDVDYLADRAREIFAISKNVLVSKYLENAVEMDVDFVSDGTSYSICGIIVHIEEAGVHSGDATMVYGPGIVPVDIEKKIEGIVGSMVREFRLIGLSNLQIAVRDGDVYVIELNARSSRSVPFISKATGIDWVRLAVECMIGSRIENKRMEAKSYFLKVSVFPFSKFSDMDVVYGPEMKSTGEAMYPGRTLAEALRKSLQRSISSVLITVRDEDKPRIVDIARILLEKGVKLYATAGTSKFLADHGIPTETLYRVRDRREPRILDMISSGSIDMVINTTEMTAGAVRDGFKIRRICIMRGIPLIMNINLARAYAEALGQVEVDYREIGDYLQVS
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: ESF1_MOUSE
Sequence: MSSKQEIMDDQRFRRVSKDPRFWEMPEKERKVKIDKRFRAMFHDKKFKLNYAVDKRGRPISHSTTEDLKRFYDLSDSDSDLSDEESKILSQKKAKQKKKQTKKEAKSIEKPIEEKKKETKKTDQKDSINKHDLNNSERVQKMKNSQKPQKIDSEISPKKDNEEFLQNKKKKRGTTDLSVEALPKGKLRTKDSSTSEMVKSSTMSSSKAKREKQSVVPVIMAKDNDGKMPDEDALEEDSDSASELGSDEESEDEIISDGKTSADEDESEEEDEEEEEDSEEEEEEEEEDESDSGPDLARGKGNVETSSEDEDDLADLFPEEPGFEHAWRELDKDAPRADEITRRLAVCNMDWDRLKAKDLLALFNSFKPKGGVVFSVKIYPSEFGKERMKEEQVQGPVELLSIPEDAPEKDWASREKLRDYQFKRLKYYYAVAECDSPETASKIYEDCDGLEFESSCSFIDLRFIPDDITFDDEPKDVALEVDLTAYKPKYFTSAAMGTSTVEITWDETDHERITTLNRKFKKDELLDMDFQAYLASSSEDEEEVEEAPEGEEGVNIGEDGKTKKSQKDDEEQIAKYRQLLQVIQEKEKKGKENDMEMEIKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKKEKKRLKKKQKALAEEDSEDELPSDVDFNDPYFAEEVKKIGIKKKSMKSAKDSASSEEETDLEKQKAEMALLVMDEEEDSKKHFNYDKIVEHQNLSKKKKKQLMKKKELVEDDFEVNVSDARFQAMYTSHLFNLDPSDPNFKKTKAMEKILEEKARHRERKEELLIQAVERAQQDTGKPTQKQPMDPALSMLIKSVKNKTEQFQARKKQRVK
What is the function of this protein?
May constitute a novel regulatory system for basal transcription.  Negatively regulates ABT1 (By similarity).
What are the official names of this protein?
ESF1 homolog, ABT1-associated protein.
What is the protein family that this protein belongs to?
Belongs to the ESF1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: SYYC_BOVIN
Sequence: MGDSLSPEEKLSLITRNLQEVLGEEKLKEILKERELKVYWGTATTGKPHVAYFVPMSKIADFLKAGCEVTILFADLHAYLDNMKAPWDVLELRTSYYENVIKAMLESIGVPLEKLRFIKGTDYQLSKEYTLDVYRLSSVVTQHDAKKAGAEVVKQVEHPLLSGLLYPGLQALDEEYLKVDAQFGGVDQRKIFTFAEKYLPALGYSKRIHLMNPMVPGLTGSKMSSSEEESKIDLLDRKEDVKKKLKKAFCEPGNVENNGVLAFIRHVLFPLKSEFVILRDEKWGGNKTYTAYLDLEKDFADEVVHPGDLKNSVEVALNKLLDPIREKFNTPALKKLSSAAYPDPSKQKPAVKGPAKNSEPEEVIPSRLDIRVGKVISVDKHPDADSLYVEKIDVGEAEPRTVVSGLVQFVPKEELQDRLVVVLCNLKPQKMRGVKSQGMLLCASVEGVNRKVEPLDPPAGSAPGERVFVKGYEKGQPDEELKPKKKVFEKLQADFKISDEYIAQWKQTNFMTKMGSVSCKSLKGGNIS
What is the function of this protein?
Tyrosine--tRNA ligase that catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).  Also acts as a positive regulator of poly-ADP-ribosylation in the nucleus, independently of its tyrosine--tRNA ligase activity.  Activity is switched upon resveratrol-binding: resveratrol strongly inhibits the tyrosine--tRNA ligase activity and promotes relocalization to the nucleus, where YARS1 specifically stimulates the poly-ADP-ribosyltransferase activity of PARP1.
What are the official names of this protein?
Tyrosine--tRNA ligase, cytoplasmic, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF3_PIPCE
Sequence: MPRSQINGNFIDKTFSIVANILLRIIPTTSGEKEAFTYYRDGMSAQSEGNYAEALQNYYEATRLEIDPYDRSYILYNIGLIHTSNGEHTKALEYYFRALERNPFLPQAFNNMAVICHYRGEQAIRQGDSEIAEAWSDQAAEYWKQAISLTPGNYIEAHNWLKITGRFE
What is the function of this protein?
Essential for the assembly of the photosystem I (PSI) complex.  May act as a chaperone-like factor to guide the assembly of the PSI subunits.
What are the official names of this protein?
Photosystem I assembly protein Ycf3.
What is the protein family that this protein belongs to?
Belongs to the Ycf3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: MUTT_PROVU
Sequence: MMDKKKLHIAAGVICDKHNNVFIAQRPLKSHMGGFWEFPGGKLEDNETPEQALLRELQEEIGIDVTQCTLLDTVAHDFPDRHITLSFFLVTEWKNELTEKKGSCRVGHLLCL
What is the function of this protein?
Specifically hydrolyzes both 8-oxo-deoxyguanosine triphosphate (8-oxo-dGTP) and 8-oxo-guanosine triphosphate (8-oxo-GTP) to the related monophosphates, thereby cleaning up the nucleotide pools and preventing misincorporation of 8-oxoGua into DNA and RNA.  It prevents replicational errors by removing an oxidatively damaged form of guanine (8-oxo-dGTP) from DNA and the nucleotide pool.  8-oxo-dGTP can be inserted opposite dA and dC residues of template DNA with almost equal efficiency thus leading to A. T to G. C transversions.
What are the official names of this protein?
8-oxo-dGTP diphosphatase, 8-oxo-dGTPase, 7,8-dihydro-8-oxoguanine-triphosphatase, Mutator protein MutT, dGTP pyrophosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
Protein: WDY_DROGR
Sequence: MSMVYLASGDSNANIEYQTISSTATQQLTQEQSERLHDRITKAQLQKLYDLFKSSPDQMVGYSELRHMLEDVDITFTDYTYTRLFLKINQNSDFMIDWNEFVSYLIFGFQEEDPSSQKEALTMPISAPPVVRKTEHRSAVCCITLLKVKSDQTPMEEIPELSANYSFGGEDSPENSGMWVTASREGQLRFWSAHMEPLRSAVSESSNLPYAVYCMSYAFYNNGKTHSKLVLGDYAGNVRILSYSPYLRGPFQAKPGAALVELVWADVLKGRIPLLIPREHINLHSELISCVYYSLHMNTLFASAEYRNTKKYRGRCPGLIMVSNDDRNNFRIPLGVSVFYVAESKNILVTGGPDTFVRIWDVYISSEPSAILTGHNGGIVAVFVQPEENKVYSVDYHKVIKVWDLQEHTLLQTFGELVRIIHHSETDIKYYYHSHLRDLLVAGRKLIQIKCCPRVRVDLTDGNTHAAPVSVVLYNRLFRNIVTCGLDSYIIVWDPWTGRRKIIMKNCHTKMIYGEIIDIEITAACFDPLEQFLLTGARDGSLKIWNYNNAVVVRNMSIQPDQEVTAVIWVIDRILAMGWDRQVTEFNDVAGREYGDPKKWAKFHTDDITCADVKLGEGVVTATYSGEIIFWKLETGQPYRRYNVMNPYQFIELKLNTEEEKLTRRSKRISSLMGAGRRTLVLQNFKPDEIKDYGANIPVSVQAVLFLQKRPMTKDHGSVFISLDTGYIQVYSHHQHGGFIKQFFAVHKVGDCVLTMASDRKNRFLYTGTAFGYIKIWHIVNYCIPQAEKTEVCMPRLRLDFIFLRKDLFLTRAKRVIRNQPEPMLVSSYKGHLKAINSIGFINLPKILFTGSHDYSCRLWTQGGRYLGTLGTVLPWSKLTPFERAGEDNRAYRLPPDIKKVASSTTLKVISGIQHTGTVKRAKAVDEREDERDVEEAASDVKNMFDRPLREPILGHHFQLPGRSVIEQRIDLDTTELCIPVYTHLRVYPSEMMEHLPTPPVIGQVRAENYLDHYMPVVGKVDPHDSAINIREPQKRAKAGSSSLLPARAGYSLGKPKTNSVLGMPRSSGAGLCKPRTSFTLSDYTPGNPKADFSSRNMKSNLSSGSPKAGIPKADSSHGSAKASCRLGSPKPDYISIKKRASFSPGTTPKTDFSPKAGKPKTNTMKSSNSH
What are the official names of this protein?
WD repeat-containing protein on Y chromosome, WD40 Y.
Protein: HLYC2_ECOLX
Sequence: MNINKPLEILGHVSWLWASSPLHRNWPVSLFAINVLPAIRANQYVLLTRDNYPVAYCSWANLSLENEIKYLNDVTSLVAEDWTSGDRKWFIDWIAPFGDNGALYKYMRKKFPDELFLAIRVDPKTHVGKVSEFHGGKIDKHLANKIFKQYHHELITEVKNKTDFQFFINRLRGN
What is the function of this protein?
Protein-lysine myristoyltransferase that catalyzes myristoylation of the protoxin (HlyA) at two internal lysine residues, thereby converting it to the active toxin.
What are the official names of this protein?
Protein-lysine myristoyltransferase HlyC, Hemolysin C, Hemolysin-activating lysine-acyltransferase HlyC, Toxin-activating protein C, 2001.
What is the protein family that this protein belongs to?
Belongs to the RTX toxin acyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHIC_SOLLC
Sequence: MRLSEFTTLFLLFSVLLLSASAEQCGSQAGGALCASGLCCSKFGWCGNTNEYCGPGNCQSQCPGGPGPSGDLGGVISNSMFDQMLNHRNDNACQGKNNFYSYNAFVTAAGSFPGFGTTGDITARKREIAAFLAQTSHETTGGWPTAPDGPYAWGYCFLREQGSPGDYCTPSSQWPCAPGRKYFGRGPIQISHNYNYGPCGRAIGVDLLNNPDLVATDPVISFKSAIWFWMTPQSPKPSCHDVITGRWQPSGADQAANRVPGFGVITNIINGGLECGHGSDSRVQDRIGFYRRYCGILGVSPGENLDCGNQRSFGNGLLVDIM
What is the function of this protein?
Defense against chitin-containing fungal pathogens.
What are the official names of this protein?
Basic 30 kDa endochitinase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 19 family. Chitinase class I subfamily.
What are the subcellular locations of this protein?
Vacuole. Secreted, cell wall. Note=Vacuolar, protoplast and cell wall.
Protein: METX_YEAST
Sequence: MVSAQVATELGQPIPLDTQHAVSVCFPTWKSVISYVEKDPKVLGCLKSGYPRFWIHPSIQKLRDILIEKYAKENETCFCFPSYRVAKRCREYVRRKCAHRNGKVRILQLATAKPINEEQKTWKRECKIAVVFVDGAYENILKQYWQYTGEIISSRLAEYVLHELFMVEKKSSPAEEKEYIEMRYGRNLNFAFADRAKELIKKRIATKVIDKDEHDEEENYHFLAGNQDEQDFQDTFLDSSLNEANHGEDHDGGISGEVDSQEEPHNGLVSTIPPEPIEMSTIEEEQSVEEDAGRCALRVCPERDVFLFPSGMASIFTAHRLLLQWDSLRLNRSRNGSDVTSSPPNKKTVIFGFPYADTLHVLQEFNETYFLGEGDESSMKELTKILHSGEQILAVFIETPSNPLLKMGNLLELKRLSELFGFFIIIDETVGGIVNIDGLPFADIVCSSLTKTFSGDSNVIGGSMVLNPQSRVYEFASRFMQLEDEYEDLLWCEDAIYLERNSRDFIARTIRINYSTEYLLDKILKPHVGENKLFKKIYYPNLTSKETLTNYDMVRCKKEGGYGGLFSLTFHDEDHAAAFYDNLKLNKGPSLGTNFTLAFPYTLMTYYHELDMAEKFGVERNLLRISVGLESQSILGKIFQEAIDKTVEI
What is the function of this protein?
Catalyzes the formation of L-cystathionine from O-succinyl-L-homoserine (OSHS) and L-cysteine, via a gamma-replacement reaction.  In the absence of thiol, catalyzes gamma-elimination to form 2-oxobutanoate, succinate and ammonia (By similarity).
What are the official names of this protein?
Putative cystathionine gamma-synthase YML082W, O-succinylhomoserine (thiol)-lyase.
What is the protein family that this protein belongs to?
Belongs to the trans-sulfuration enzymes family. MET7 subfamily.