PharMolix/UniProtQA huggingface dataset:
Protein: TIMP1_CANLF
Sequence: MAPFAPLASCILLLLWVTAPSRACTCAPPHPQTALCNSQIVIRAKFVGTAEVNQTDLNRRYEIKMTKMFKGFSALGNASDIRFVDTPALESVCGYLHRSQNRSEEFLVAGNLRDGHLQINTCSFVAPWSSLSTAQRRGFTKTYAAGCEGCTVFTCSSIPCKLQSDTHCLWTDHFLTGSDKGFQSRHLACLPREPGICTWQSLRPRMA
What is the function of this protein?
Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor.  Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16.  Does not act on MMP14.  Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1.  Plays a role in integrin signaling.
What are the official names of this protein?
Metalloproteinase inhibitor 1, Tissue inhibitor of metalloproteinases 1, TIMP-1.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I35 (TIMP) family.
What are the subcellular locations of this protein?
Secreted.
Protein: GATA_ZYMMO
Sequence: MTRLTDLGVTDLRDGIAKGDFSAKEVAESFLTATNEAEKLNAFITLTPDHALKQAEKADKDRASGQLKPLSGVPLGIKDLFCTNGYRTTAASKIIDNFVPPYESTITEKLFSAGAGMVGKLNLDQFAMGSSNETSAFGNVISPWRQKGDDTALTPGGSSGGSAAAVAAKLVPAATGTDTGGSIRQPASFTGITGLKPTYGRCSRYGVIAFASSLDQAGPMAHSVKDCAALLEVMAGFDPKDSTSVDVMVPNWEKLLSSDIRGKKIGIPKEYRVDGMAPEIESLWQRGIDMMKDAGAEIIDVSLPHTQHALAAYYIIAPAEASSNLARYDGVRYGERKTPEGGNLADMYAATRAAGFGDEVKRRIMIGTYVLSAGFYDAYYIKAQKIRALIARDFEAAFDKCDILLTPATPTAAFALGQKQEDPIAMYLNDVFTVPASLAGLPAMTVPVGLNEQGLPLGLQLIGKPLDEQSVLNAGLALEERAGFTSQPKKWW
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: NSH3_ARATH
Sequence: MLTSPTLKSLWFLFTILGLLGQNLPCVLSSSHRILVDTDVDTDDLFAILYLLKLNKSEFDLVGITLSANAWTNAGHAVNQVYDLLHMMDRDDIPVGVGGEGGISDDGTIHSDVGGYFPIIEQGMTTTGECRYRQAIPKGLGGLLDIDSNYGFRKQFLPQGNRRYTPLQQPTAQKVIVDKISEGPTTVILLGSHTNFALFLMSNPHLKHNIQHIYIMGGGVRSQNPTGCCPANSTVAECQPRQCGNRGNLFTDYTSNPYSEFNIFADPFAAYQVFHSGVPVTLVPLDATNTIPINQKFFETFENNYQRTYEAQYVFLSLKIARDTWFDDEFYKSYFMWDSFTAGVAVSIMRNSANKNNKNGENDFAEMEYMNITVVTSNKPYGRSDGSNPFFDNRRTPKFNLALGGVHSGHVQTGLRDPTCLPKSGIGRGKCKDGYTQEISGSDSVRVLVATRAKPNINIKSKLDREFYVDFLEVLNRPEETGRFNFSSQFPYYKEELFRPDLSKTRPGKPVVFDMDMSAGDFLSLFYLLKVPVDKIDLKAIIVSPTGWANAATIDVVYDLLHMMGRDDIPVGLGDMLALNQSDPIFPPVGGCKYVKAIPRGCGGFLDSDTLYGLARDLPRSPRRYTAENSVTHGAPRDTDRPELRQPLAIEVWQNLTKSGNGVSKITVLTNGPLTNLAKIISSDKKSSSLIKEVYIVGGHINREKSDKGNIFTIPSNAYAEFNMFLDPLAAKTVLESALNITLVPLATQHKLSSFQTMLDRLYSSTKTPEARFVKRLLVRLQALHQKHRRYTHIDMFLGEVLGAVLLGGDDASLKPKMRAEHIKVIAEGDESRDGKILIDKLRGKQIKILERVDLISISESFASRLDDKKQSAVIGSFEEQKKIWSTPPS
What is the function of this protein?
Extracellular purine-specific hydrolase present in the apoplastic fluid involved in the degradation of extracellular nucleosides, including inosine and adenosine, and which may participate in wound and pathogen responses (e. g.  Botrytis cinerea).
What are the official names of this protein?
Nucleoside hydrolase 3, Adenosine nucleosidase, Inosine nucleosidase, Purine nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast. Note=Present in the apoplastic fluid.
Protein: BPAC_BURP2
Sequence: MNRIFKSIWCEQTRTWVAASEHAVARGGRASSVVASAGGLEKVLKLSILGAASLIAMGVVGPFAEEAMAANNAGVCLTYNGSSNNTSGTGGWFADGCKSAGWVQGMVTNSKTDWVGLTADDTQIVLDGSAGSIYFRTGGINGNVLTMSNATGGVLLSGLAAGVNPTDAVNMSQLTSLSTSTATGITSLSTSTATSIASLSTSMLSLGVGVVTQDASTGAISVGANSPGLTVDFAGGQGPRTLTGVAAGVNATDAVNVGQLASLSTSTAAGLSTAASGVASLSTSLLGAVGDLASLSTSASTGLATADSGIASLSTSLLGTADNVTSLSTSLSTVNANLAGLQTSVDNVVSYDDPSKSAITLGGAGVTTPVLLTNVAAGKIAATSTDAVNGSQLYTLQQEFSQQYDLLTSQVSSLSTSVSGLQGSVSANTGTASGDNSTASGDNATASGTNSTANGTNSTASGDNSTASGTNASASGENSTATGTDSTASGSNSTANGTNSTASGDNSTASGTNASATGENSTATGTDSTASGSNSTANGTNSTASGDNSTASGTNASASGENSTATGTDSTASGSNSTANGTNSTASGDNSTASGTNASATGENSTATGTDSTASGSNSTANGTNSTASGDNSTASGTNASATGENSTATGTDSTASGSNSTANGTNSTASGDNSTASGTNASATGENSTATGTDSTASGSNSTANGTNSTASGDNSTASGTNASATGENSTATGTDSTASGSNSTANGANSTASGDNSTASGTNASATGENSTATGTDSTASGSNSTANGTNSTASGNNSTASGTNASATGENSTATGTDSAASGTNSTANGTNSTASGDNSTASGTNASATGENSTATGTASTASGSNSTANGANSTASGAGATATGENAAATGAGATATGNNASASGTSSTAGGANAIASGENSTTNGANSTASGNGSSAFGESAAAAGDGSTALGANAVASGVGSVATGAGSVASGANSSAYGTGSNATGAGSVAIGQGATASGSNSVALGTGSVASEDNTVSVGSAGSERRITNVAAGVNATDAVNVGQLNSAVSGIRNQMDGMQGQIDTLARDAYSGIAAATALTMIPDVDPGKTLAVGIGTANFKGYQASALGATARITQNLKVKTGVSYSGSNYVWGAGMSYQW
What is the function of this protein?
Involved in virulence (PubMed:23716608, PubMed:24731253).  Mediates adherence to human respiratory epithelial cells (PubMed:24731253).
What are the official names of this protein?
Autotransporter adhesin BpaC, Type 5 secretion system autotransporter BpaC.
What is the protein family that this protein belongs to?
Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
What are the subcellular locations of this protein?
Cell surface. Cell outer membrane. Note=The C-terminal translocator domain is localized in the outer membrane and the passenger domain is at the cell surface.
Protein: FEN1_ASPFU
Sequence: MGIKHLFQVIQENAPDAIKAGDIKNHFGRKVAIDASMSIYSFLIAVRSEGQQLMSESGETTSHLMGMFYRTLRMVDNGIKPLYVFDGAPPKLKSGELAKRTARKAEATEAHEEAKETGTAEDVEKFSRRTVRVTREHNAECKKLLKLMGIPYIDAPTEAEAQCAVLARAGKVYAAASEDMDTLCFEAPILLRHLTFSEQRKEPIQEIHLNRALEGLGMDRKQFIDLCILLGCDYLEPIPKVGPNTALKLIREHGSLEKVVEAIENDPKKKYVIPEYWPYQDARELFLHPDVREADHPECDFKWEAPDVEALVEFLVKDKGFNEDRVRNGATRLQKNLKTAQQSRLEGFFKPVARTDEEKASLKRKHDEKLQEQKKRKKEEAKAKKEAKAKPRGAA
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: SOTB_SHIFL
Sequence: MTTNTVSRKVAWLRVVTLAVAAFIFNTTEFVPVGLLSDIAQSFHMQTAQVGIMLTIYAWVVALMSLPFMLMTSQVERRKLLICLFVVFIASHVLSFLSWSFTVLVISRIGVAFAHAIFWSITASLAIRMAPAGKRAQALSLIATGTALAMVLGLPLGRIVGQYFGWRMTFFAIGIGALVTLLCLIKLLPLLPSEHSGSLKSLPLLFRRPALMSIYLLTVVVVTAHYTAYSYIEPFVQNIAGFSANFATALLLLLGGAGIIGSVIFGKLGNQYASALVSTAIALLLVCLALLLPAANSEIHLGVLSIFWGIAMMIIGLGMQVKVLALAPDATDVAMALFSGIFNIGIGAGALVGNQVSLHWSMSMIGYVGAVPAFAALIWSIIIFRRWPVTLEEQTQ
What is the function of this protein?
Involved in the efflux of sugars.  The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites.
What are the official names of this protein?
Probable sugar efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SFH1_KLULA
Sequence: MSLVPQAYLSNFHNRVKNEDVPLFTAAQLSRNKRGKQVNYAEFDTDLLDEFIDKNDEDDLEDDVDDSDGRRRGGDYYDQVDGSDGGAAAAAATAAAAAGLGEDGGIGEGTPGSGDPGAVTGGTPAADTGPDGTNDGTAGTSNPSSELDRIKLNDLPDLESQDDSATPLALLKYPRIRETFVQSRIAISYKDLLGDSIQDPQQVDIESPIMVPIRLNVEFSGHKLADFFMWNLNDHSMTPEQFATILCQDLDFPVLSNPNNSPYTQIISMINEQLQEYETLASLQVPDLHVIINLTANLDSKLYDDTFEWNLNDDSLCPEQFAELVVQDLGLQREFVPAIAHSLHESLLKVKKDWLEGNLNLAHVENKAAFGYTSGIRLDIDTLGASWFPKVEVLSQWEIEKREIEKERNMRRLKRESAKVDDGRSRRRGKRRMDDLETTLRI
What is the function of this protein?
Part of the chromatin structure-remodeling complex (RSC) which is involved in transcription regulation and nucleosome positioning.  RSC is responsible for the transfer of a histone octamer from a nucleosome core particle to naked DNA.  The reaction requires ATP and involves an activated RSC-nucleosome intermediate.  Remodeling reaction also involves DNA translocation, DNA twist and conformational change.  As a reconfigurer of centromeric and flanking nucleosomes, RSC complex is required both for proper kinetochore function in chromosome segregation and, via a PKC1-dependent signaling pathway, for organization of the cellular cytoskeleton.  This subunit is essential for mitotic growth and required for cell cycle progression (By similarity).
What are the official names of this protein?
Chromatin structure-remodeling complex subunit SFH1, RSC complex subunit SFH1, SNF5 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the SNF5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ZAPB_SHEAM
Sequence: MSLELLSQLETKIQTALETIELLKLELDEEKEKAANLAEQNHQLKQELSSWNDKITGLVGLLSNQVD
What is the function of this protein?
Non-essential, abundant cell division factor that is required for proper Z-ring formation.  It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle.  Its recruitment to the Z-ring requires functional FtsA or ZipA.
What are the official names of this protein?
Cell division protein ZapB.
What is the protein family that this protein belongs to?
Belongs to the ZapB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the septum at mid- cell, in a FtsZ-like pattern.
Protein: LIN41_XENTR
Sequence: MASFPESDFQLCPLCKEMCVSTSSSSAGSAGGGTGLASAPPRRLHVLPCLHAFCRQCLEGRRSPGDSLQLRCPVCDHKVLISEAGMDALPSSTFLHLSNLLDAVVGAADEQQQSNGGRTASNRQRSASCSSSGLLRRAPPSQSEPRCSSCDDGNGASSHCLDCQENLCDNCLRAHQRVRLTKDHFIERFPASPCSSAASSAATTSSSSSSAFSLLPVYPERLYCQQHDEEVLHFYCDSCSVPICRECTMGRHAGHSFVYLQEALQDSRALTIQLLADAQQGRQAIQLSLEQAQALAEQVEMKAKVVQSEIKAVTSRHKKALEERECELLWKVEKIRQVKAKSLYHQVEKLHQALNKLDSTINAVQQVLEEGCTMDILIARDRVLAQVQDVKNARGLLQLQEDDRIMFTPPDQALYLAIKSLGLVSSGAFAALTKATGEGLKRALQGKVASFTVIGYDHDGEARLSGGDLITVLVMGPDGNLFAAEVSDQLNGTYLVSYRPQLEGEHLISVMVCNQHIENSPFKVNVKSGRCYLGIGLPTLSFGGEGDHDGKLCRPWGVCVDREGYIIVADRSNNRVQIFKPCGTFHHKFGSLGSRPGQFDRPAGVACDNSRRIVVADKDNHRVQIFTFEGQFLLKFGEKGTKNGQFNYPWDVAVNSEGKILVSDTRNHRVQLFGPDGTFLNKYGFEGALWKHFDSPRGVAFSQDGYLVVTDFNNHRLLIIKPDCQSAHFLGTEGTGNGQFLRPQGVAVDQEGRIIVADSRNHRVQIFEPNGSFLCKFGTQGSGFGQMDRPSGIAVTPDGTIVVVDFGNNRILAF
What is the function of this protein?
E3 ubiquitin-protein ligase that cooperates with the microRNAs (miRNAs) machinery and promotes embryonic stem cells proliferation and maintenance.  Binds to miRNAs and participates in post-transcriptional repression of transcripts.  Required to maintain proliferation and prevent premature differentiation of neural progenitor cells during early neural development.
What are the official names of this protein?
E3 ubiquitin-protein ligase TRIM71, Protein lin-41 homolog, RING-type E3 ubiquitin transferase TRIM71, Tripartite motif-containing protein 71.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm, P-body.
Protein: RS7_METHJ
Sequence: MSEEVSAPARLLFNRWDTSEVTIRDPGIARYVNLNSMMVPHSCGRLTRQEFHKANMLIVERLINQLMRTEVNTGKKQLAIRIVRDAFEIVHQKTKKNPIEVLCDAVANAGPREETVRLKYGGINVPKSVDTAPMRRVNTAVGLIAAGVYSASHKKKKPVANALAEELIAAANGDVKCYSVAKREERERVAKSAR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: VATD_METKA
Sequence: MTQEILEDVNPTRMELLKLQDRIELAKKGHKLLKEKRDALIMEFFEMVKRASEIREQAVKKLMEAYSKLAAAKVTVGEIGVERASMATGEEIKVDVGSRNVMGVVVPIIERVSEDGGSKVVYGFADTSGALDEAMRAFTEAIDAVLELAEIEETLRLMAEEIERTKRRVNALEHIVIPRLENTEKYIEMKLDEQERENFVRLKRVKDLIERKKLKEELERVVEEGAELPSFE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit D, V-ATPase subunit D.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase D subunit family.
Protein: HOFB_HAEIN
Sequence: MTSYALLHTQRVTAKNGEVFTISPDLWERNQQQQSLLLRYFALPLKEENNRLWLGVDSLSNLSACETIAFITGKPVEPILLESSQLKELLQQLTPNQMQVEEQVKFYQHQETHFEQEDDEPVIRLLNQIFESALQKNASDIHLETLADQFQVRFRIDGVLQPQPLISKIFANRIISRLKLLAKLDISENRLPQDGRFQFKTTFSDILDFRLSTLPTHWGEKIVLRAQQNKPVELSFSELGMTENQQQAFQRVLSQPQGLILVTGPTGSGKSISLYTALQWLNTPDKHIMTAEDPIEIELDGIIQSQINPQIGLDFNRLLRTFLRQDPDIIMLGEIRDEESAMIALRAAQTGHLVLSTLHTNDAISAISRLQQLGIQQYEIKNSLLLVIAQRLVRKLCSKCGGNLANSCDCHQGYRGRIGVYQFLHWQQNDYQTDFKNLRASGLEKVSQGITDEKEIERVLGKNL
What are the official names of this protein?
Protein transport protein HofB homolog.
What is the protein family that this protein belongs to?
Belongs to the GSP E family.
Protein: CSF1R_DANRE
Sequence: MFFALLFLIGILLGQVQGWSEPRIRLSSGALAGTDVILESGSPLQLVCEGDGPVTFLPRLAKHKRYISKEVGKIRSFRVEKTTVDFTGTYKCVYMNGNDSNLSSSVHVFVRDSRVLFVSPSTSLRYVRKEGEDLLLPCLLTDPEATDFTFRMDNGSAAPYGMNITYDPRKGVLIRNVHPGFNADYICCARIGGAEKVSKIFSINIIQRLRFPPYVYLKRNEYVKLVGERLQISCTTNNPNFYYNVTWTHSSRMLPKAEEKSTMEGDRLAIESILTIPSVQLSHTGNITCTGQNEAGANSSTTQLLVVEEPYIRLSPKLSSKLTHRGLSIEVSEGDDVDLGVLIEAYPPLTSHKWETPTSHNASLPENRFFNHNDRYEALLLLKRLNFEEIGQYTLNVKNSMKSASITFDIKMYTKPVARVKWENVTTLSCRSYGYPAPSILWYQCTGIRTTCPENTTDLQPIQTQTVEFQKESFGAVGVESVLTVGPNRRMTVVCVAFNLVGQGSDTFSMEVSDQIFTSAMCGSTVAMVVLGLLLIFMIYKYKQKPRYEIRWKIIEATNGNNYTFIDPTQLPYNEKWEFPRDKLKLGKTLGAGAFGKVVEATAYGLGKEDNITRVAVKMLKASAHPDEREALMSELKILSHLGQHKNIVNLLGACTHGGPVLVITEYCCHGDLLNFLRSKAENFLNFVMTIPNFPEPMTDYKNVSTERMFVRSDSGISSTCSDHYLDMRPVTSRPTNSALDSSSECQEDSWPLDMDDLLRFSSQVAQGLDFLAAKNCIHRDVAARNVLLTNSRVAKICDFGLARDIMNDSNYVVKGNARLPVKWMAPESIFECVYTVQSDVWSYGIMLWEIFSLGKSPYPNILVDSKFYKMIKCGYQMSRPDFAPPEMYTIMKMCWNLDAAERPTFSKISQMIQRMLGETSEQQDTQEYKNIPTEAEAEQQLESCDPVKHEDESFETSCDQEEEDQPLMKPNNYQFC
What is the function of this protein?
Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes.  Plays an important role in innate immunity and in inflammatory processes.  Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development.  Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration.  Activates several signaling pathways in response to ligand binding (By similarity).
What are the official names of this protein?
Macrophage colony-stimulating factor 1 receptor, CSF-1 receptor, CSF-1-R, CSF-1R, M-CSF-R, Proto-oncogene c-Fms homolog.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=The autophosphorylated receptor is ubiquitinated and internalized, leading to its degradation.
Protein: CITD_LACH4
Sequence: MEIKTTAVAGTLESSDIQIMISKGSNGIEIDLESEVKKAYGDQIEKVITETLKKYGLENAKVKATDKGALDCVIKARTLAVAQRATETQDKPDLEVL
What is the function of this protein?
Covalent carrier of the coenzyme of citrate lyase.
What are the official names of this protein?
Citrate lyase acyl carrier protein, Citrate lyase gamma chain.
What is the protein family that this protein belongs to?
Belongs to the CitD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYI_PARP8
Sequence: MSNKKADSKPQARYPVNLLDTPFPMRGDLPRREPQWVKDWQERKIYEKIRAASKGRKKFILHDGPPYANGDIHLGHAVNKILKDMIVKARNLAGFDAVYVPGWDCHGMPIEIQIEKQFGKSLPAAEVMQKARAYATEQIEKQKAGFRRLGVLGDWDNPYKTMNFANEAGEIRALAKIMEKGYVFRGLKPVNWCFDCGSALAEAEVEYKDKTDPTIDVMFTFADPEKTAHAFGLAALPRNEGGIVIWTTTPWTIPANQALNLHPEIVYALVDTPRGLLILAEERVEACLKSYGIAGTVIATAPGAKLANLRFNHPLASAHPSYKRTSPVYLGDYVTTETGTGIVHSSPAYGVEDFISCKTHGMADSDILSPVMGDGRYIESLALFGGLSIWDANPKIVEALDEAGTLLRTEKYLHSYMHCWRHKTPIIYRATSQWFAGMDIKPNDSDKTLRETALEGIEATAFYPSWGKQRLFAMIANRPDWTLSRQRQWGVPMAFFVHKETGELHPRTLELLEEVAKRVEVSGIEAWQTLDPRELIGDDANMYEKNRDTLDVWFDSGTTHWHVLRGSHKDELQFPADLYLEGSDQHRGWFHSSLLTASMLDGRPPYNALLTHGFTVDGEGRKMSKSLGNGIDPHEVSNRLGAEIIRLWIASTDYSGELAISEEILKRVTESYRRIRNTLRFLLANLSDFDIGKHARPVGEWLEIDRYAVALTANLQADILSHYDRYEFHPVVAKLQTFCSEDLGGFYLDVLKDRLYTTAADSKARRSAQTALYHIAHGLLRLMAPFLSFTAEEAWKVFQPQSETIYTETYHAYPDVPEASTLLDKWTLLRAVRSDVTKALEEARVANQIGSSLQAEVEIRAAGARHDALASLGADLKFVLITSGATVVKVDSVDEEGVDVITSKYLKCERCWHYRKDVGESAEHPTLCGRCISNLFGNGETRSAA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRBB1_MOUSE
Sequence: MSQAAKASATTAVNPGPDGKGKGAPSTGPAPAPGPTPVPASVPRPAAKVGDLPPGSYRLIVFEQENFQGRRVEFSGECLNLGDRGFDRVRSLIVVSGPWVAFEQSAFRGEMFVLEKGEYPRWDTWTSSYRSDRLMSFRPIRMDSQEHKICLFEGANFKGNTMEIQEDDVPSLWVYGFCDRVGSITVSGGTWVGYQYPGYRGYQYLLEPGDFRHWNEWGAFQPQMQAVRRLRDRQWHQEGCFPVLTAEPPK
What is the function of this protein?
Crystallins are the dominant structural components of the vertebrate eye lens.
What are the official names of this protein?
Beta-crystallin B1, Beta-B1 crystallin.
What is the protein family that this protein belongs to?
Belongs to the beta/gamma-crystallin family.
Protein: IF3_STRTD
Sequence: MKIIAKKDLFINDEIRVREVRLVGLDGEQLGIKPLSEAQAIADDANVDLVLIQPQATPPVAKIMNYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPVIDKGDFETKLRNGRKFLEKGNKVKVSIRFRGRMITHKEIGAKVLAEFAEKTQDIAIIEQRAKMDGRQMFMQLAPIPDKK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNFA_VIBCH
Sequence: MTEYLLLLIGTVLVNNFVLVKFLGLCPFMGVSKKLETAIGMGLATTFVLTLASVCAYLVESYVLRPLGIEYLRTMSFILVIAVVVQFTEMVVHKTSPTLYRLLGIFLPLITTNCAVLGVALLNINENHNFIQSIIYGFGAAVGFSLVLILFASMRERIHVADVPAPFKGASIAMITAGLMSLAFMGFTGLVKL
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit A, Rnf electron transport complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL22_LIMRD
Sequence: MAENITSAKATAKMVRVSARKVRLVLDAIRGKSVAEAFAILKFTPRGAASDVEKVLKSAVANAENNFDLDRASLVVSEAFANEGPTLKRFRPRAKGSASPINKRTSHITVVVTER
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: FLVC1_FELCA
Sequence: MVKLNDEEGAAMAPGHQPTNGYLLVPGGEPPGKVSAELQNGPKAVCLTLNGVSRDSLAAAAEALCRPQTPLAPEEETQTRLLPTGPGEETPGTEGSPAPQTALSARRFVVLLIFSLYSLVNAFQWIQYSVISNVFEGFYGVSSLHIDWLSMVYMLAYVPLIFPATWLLDTRGLRLTALLGSGLNCLGAWVKCASVQQHLFWVTMLGQCLCSVAQVFILGLPSRIASVWFGPKEVSTACATAVLGNQLGAAIGFLLPPVLVPNTQNNTDLLACNISTMFYGTSSVATFLCFLTIIAFKEKPQYPPSQAQAALQNSPPAKYSYKKSIRNLFRNVPFVLLLITYGIITGAFYSVSTLLNQMILTYYKGEEVSAGKIGLTLVVAGMVGSILCGFWLDYTKIYKQTTLIVYILSFLGMVIFTFTLDLGYGIVVFVTGGVLGFFMTGYLPLGFEFAVEITYPESEGTSSGLLNAAAQIFGILFTLAQGKLTTDYSPKAGNIFLCVWLFLGIILTALIKSDLRRHNINIGIANGDIKAVPVEDTVEDSPTDKESKTIVMSKQSESAI
What is the function of this protein?
(Microbial infection) Confers susceptibility to Feline leukemia virus subgroup C (FeLV-C) infection, which is associated with fatal erythroid aplasia, also known as aplastic anemia (PubMed:10648427).
What are the official names of this protein?
Feline leukemia virus subgroup C receptor-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Feline leukemia virus subgroup C receptor (TC 2.A.1.28.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL35_CLOAB
Sequence: MPKMKTKKAAAKRFKATGTGKLKRGKAFRSHILTKKSTKTKRNLRKGGYVSETQEKTMKTLLPYL
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: PYRF_ECOL5
Sequence: MTLTASSSSRAVTNSPVVVALDYHNRDAAMAFVDKIDPRDCRLKVGKEMFTLFGPQFVSELQQRGFDIFLDLKFHDIPNTAAHAVAAAADLGVWMVNVHASGGARMMAAAREALVPFGKDAPLLIAVTVLTSMEASDLADLGVTLSPADYAERLAALTQKCGLDGVVCSAQEAVRFKQVFGQEFKLVTPGIRPQGSDAGDQRRIMTPEQALAAGVDYMVIGRPVTQSVDPAQTLKAINASLQRSA
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: TP2_SYLSP
Sequence: MFTLKKTLLLLFFLGTINLSLCEEERNAEEERRDGDDEMDVEVKKRFITGLIGGLMKALGK
What is the function of this protein?
Antimicrobial peptide.  Active against some Gram-positive and Gram-negative bacterial strains.  Active against fungus C. glabrata 090902 but not against C. albicans ATCC 12231.  Shows very weak hemolytic activity against human erythrocytes.
What are the official names of this protein?
Temporin-SN2.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Temporin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL14_DROME
Sequence: MPFERFVQTGRIAKASAGPLKGRLVAIVDVIDQNRVLVDGPLTGVPRQEYRLNNLHLTKYRIKFPYTAPTRIVRKAWTESDLKAQWKVSPWSVKAQNICKRSSLNDFDRFKLRYAKRQRNKLLTIAFNTLKKRTKADGTPRVLKKDRRERLRAEKAKGGKKAAAKK
What are the official names of this protein?
60S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL14 family.