PharMolix/UniProtQA huggingface dataset:
Protein: OPSG_ORYLA
Sequence: MENGTEGKNFYIPMNNRTGLVRSPYEYPQYYLADPWQFKLLGIYMFFLILTGFPINALTLVVTAQNKKLRQPLNFILVNLAVAGLIMVCFGFTVCIYSCMVGYFSLGPLGCTIEGFMATLGGQVSLWSLVVLAIERYIVVCKPMGSFKFTATHSAAGCAFTWIMASSCAVPPLVGWSRYIPEGIQVSCGPDYYTLAPGFNNESFVMYMFSCHFCVPVFTIFFTYGSLVMTVKAAAAQQQDSASTQKAEKEVTRMCFLMVLGFLLAWVPYASYAAWIFFNRGAAFSAMSMAIPSFFSKSSALFNPIIYILLNKQFRNCMLATIGMGGMVEDETSVSTSKTEVSTAA
What is the function of this protein?
Visual pigments are the light-absorbing molecules that mediate vision.  They consist of an apoprotein, opsin, covalently linked to cis-retinal.
What are the official names of this protein?
Green-sensitive opsin, Green cone photoreceptor pigment, KFH-G.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: XERD_STAES
Sequence: MNTIIEEYLNFIQIEKGLSNNTIGAYRRDLKKYKDYLEDNKISHIDFIDRQIIQECLGHLIDMGQSSKSLARFISTIRSFHQFALREKYAAKDPTVLIETPKYEKKLPDVLEIDEVIALLETPDLTKNNGYRDRTMLELLYATGMRVTEIIQLDVEDVNLIMGFVRVFGKGNKERIVPLGDTVIEYLTTYIETVRPQLLKQTTTQALFLNMHGKSLSRQGIWKIIKQYGLKANINKTLTPHTLRHSFATHLLENGADLRAVQEMLGHSDISTTQLYTHVSKSQIRKMYTQFHPRA
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerD.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPF_LEPBA
Sequence: MFRVGNGIDFHKLIHEPFRPLVLAGVEIKSEFAFLGHSDADVILHAVADAILGALSLGDIGVHFPDTDPQYKNMKSTRIIEKCLELVAEKKFKLINVDCTYVGDHPKISPIRAELNASLANITKLPLDCVSIKATTSEGMGALGRSEGVMVMATVLIESLKK
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: MURB_BORPA
Sequence: MSMSTVPACIEPVAPLAPQAQDLRCFNTLGLASHAPAFVALTEPSQLPALSALAPRFRQLVVLGGGSNVVLPASIDGLVAQVRLPGVRLVGQCADAWVVEAAAGENWHGFVTACVDNGWDGLENLALIPGTVGAAPVQNIGAYGVELADRFHSLTAWDVKGGRWVEMGAAECRFAYRDSFFKHQEPGAWVIGSVRFALPRPWQPVLDYPDLQRHAALDGAAPTARAVYDAVCAIRRAKLPDPAVVGNAGSFFKNPLVDAGTRQALLGRFPGLVSYPQPDGRYKLAAGWLIDQCGWKGRQLGAAGVHDRQALVLVNRGGAQARDIMALAAAIQGDVERRYGVRLEPEPVVVPAR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MLTF_SHEAM
Sequence: MIRLRRVLFLLTSVLVLTACQPPGLVVDAPQPKAEAETLRVGTLYGAQIYMSSGQGLSGFDYELAQKFADYLGKPLEMQPYSNRSELYDALAKGEIDLIAAGITESPNRRNRFRMGPPLYRVDQVVVYRQGNRAPESIEQLSGNLTVVADSAFVETLTRLQQTHTNLSWEQTSEKDNDELIAMIASGELNYTLAQSTSLDINRRYMPELRSGLVLEEKVPVVWLLPAQNSDALMSKLLAFWHQEKRAGTLAHLNEKYFGHVKRFDYVDTRAFIRAIDAKLPRYRPLFEEYAGDLDWRKLAAASYQESHWNPNARSPTGVRGMMMLTNATASQLGVTNRLDPRQSIRGGADYLRDLINRLPESIPENQRMWFALAAYNIGLGHLEDARRLAEAQGLNPSAWRDVKQVLPLLQKRKFYSQTRYGYARGGEAVHYVDSIRRYYDTLVWVDNQKPKDEPQLPDEIQVEETAASSGAEPPTAAPRE
What is the function of this protein?
Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product.  Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus.  Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase F, Murein lyase F.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane.
Protein: VPS51_MOUSE
Sequence: MAAAAAVGPGLGSGPGDSPEGPEADAPERRRKAHGMLKLYYGLSEGEVAGHPAGPDPLDPTDLNGAHFDPEVYLDKLRRECPLAQLMDSETDMVRQIRALDSDMQTLVYENYNKFISATDTIRKMKNDFRKMEDEMDRLATNMAVITNFSARISATLQDRHERITKLAGVHALLRKLQFLFELPSRLTKCVELGAYGQAVRYQGRARAVLQQYQHLPSFRAIQDDCQVITARLAQQLRQRFREGCSGAPEQAECVELLLALGEPAEELCEEFLAHARGRLEEELSSLEAELGPSPPAPDVLEFTDRGGNGFVGGLCQVAAAYQELFAAQGPAGAEKLAAFAQELGGRYFALVERRLAQEQGGSDNSLLVRALDRFHRRLRAPGALLAAAGLSESATEIVERVARERLSHHLQGLKAAFLSSLTDVRQALAAPRLAGKEGPSLAELLANVASSILSHIKTSLASVHLFTAKEVSFSNKPYFRGEFCSQGVREGLIVGFIRSMCQTAQSFCDSPGEKGGATPPALLLLLSRLCLDYETATISYILTLTDEQFLVQDQSPVTPVSTLCAEARETARRLLTHYVKVQGLVISQMLRKSVETRDWLSTLEPRNVRAVMKRVVEDTTAIDVQVGLLYEEGVRKAQSSDSSKRTFSVYSSSRQQGRYAPSYTPSAPMDTNLLSNIQKLFSERIDVFSPVEFNKVSVLTGIIKISLKTLLECVRLRTFGRFGLQQVQVDCHFLQLYLWRFVADEELVHLLLDEVVASAALRCPDPVPMEPSVVEVICERG
What is the function of this protein?
Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN).  The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy.  VPS51 participates in retrograde transport of acid hydrolase receptors, likely by promoting tethering and SNARE-dependent fusion of endosome-derived carriers to the TGN.  Acts as component of the EARP complex that is involved in endocytic recycling.  The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 51 homolog, Protein fat-free homolog.
What is the protein family that this protein belongs to?
Belongs to the VPS51 family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network. Recycling endosome. Note=Localizes to the trans-Golgi network as part of the GARP complex, while it localizes to recycling endosomes as part of the EARP complex.
Protein: GRPE_STRPN
Sequence: MAQDIKNEEVEEVQEEEVVKTAEETTPEKSELDLANERADEFENKYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKGLGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKLHDRILRPAMVVVYN
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIFK_SALTI
Sequence: MAEKKPELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPSVLLAYIIAGLFVFFIMRSMGEMLFLEPVTGSFAVYAHRYMSPFFGYLTAWSYWFMWMAVGISEITAIGVYVQFWFPEMAQWIPALIAVGLVALANLAAVRLYGEIEFWFAMIKVTTIIVMIIIGLGVIFFGFGNGGQAIGFGNLTEHGGFFAGGWKGFLTALCIVVASYQGVELIGITAGEAKNPQVTLRSAVGKVLWRILIFYVGAIFVIVTIFPWNEIGSNGSPFVLTFAKIGITAAAGIINFVVLTAALSGCNSGMYSCGRMLYALAKNRQLPAAVAKVSRHGVPVAGVALSILILLVGSCLNYIIPNPQRVFVYVYSASVLPGMVPWFVILISQLRFRRAHKEAIADHPFRSIMFPWANYLTMAFLVCVLIGMYFNEDTRMSLFVGVIFLLAVTLVYKVFGLNRHGTAHKVGE
What is the function of this protein?
Probable amino-acid or metabolite transport protein.
What are the official names of this protein?
Probable transport protein YifK.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYSG_YERPE
Sequence: MDYFPIFCQLQHKACLLVGGGEIAERKARLLLDAGALVTVNACEFTPQFHHWADQGQLSLISGEFVPELLADKWLVIAATDQLSVNALVYQSANQQRIFCNVVDDPKRTSFIMPSIIDRSPIMIAVSSGGKAPVLARLLREKLEALLPQHLGQLAGNLRQRVKQHFTVMTERRRFWEKLLTHDRLAQSLANNDHVQADQHVEQLFSAPLTDRGEVVLVGAGPGDAGLLTLKGLQQIQQADVVVYDRLVSDEVMNLVRRDAERIFVGKQSGHHCVPQEQINQILLQQAQSGKRVVRLKGGDPFIFGRGGEELEELAGYGIPFSVVPGITAASGCSAYSGIPLTHRDHAQSVRLVTGHAKKEGQLDWANLAAEKQTLVFYMGLSQAGEIQQQLIQHGMPATTQVALVENGTSRHQRVVSGELSQLALLSQQVSSPSLIIVGSVVSLREKLNWFSSRHHDDQPKVTECVAHVG
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: RLMM_XANOP
Sequence: MSGLLCYCRQGFEPELAAELSARAAFVGIAGYARTQRNDGYVLFVCDEAAQLAAKLQWRELIFARQKLVVIAELKGIDPKDRITPILAALEGQQRFGDLWVEHPDSDAGKPLASLARSFGNALRPALRKAGLLTDKPQPRQPRLHICFLDGDHALLAVADSADSAPWPLGIPRLKLLPEAPSRSALKLDEALLTLLTPEEREALVKPGMRAADLGAAPGGWTWVLTRQHVHVTSVDNGPLRAHVLETGLVEHLRADGFHWKPAQPVDWMVCDMVEQPRRVAERMATWVREGWCRNTIFNLKLPMKKRWDETRLCLELFEQQAEKSLIVRAKQLYHDREEITVLAMRG
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_STAA8
Sequence: MPKMKTHRGAAKRVKRTASGQLKRSRAFTSHLFANKSTKQKRQLRKARLVSKSDMKRVKQLLAYKK
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: ATPB_RHILO
Sequence: MAAKATGVVGKVRQVIGAVVDVQFGDHLPAILNALETTNVGNRLVLEVAQHLGENTVRCIAMDSTEGLVRGQEVRDTGAPITVPVGPGMLGRIINVIGEPVDEEGPVDAIEMRSIHQPAPTYVEQSTEAQILITGIKVLDLLAPYAKGGKIGLFGGAGVGKTVLIQELINNIAKAHGGYSVFAGVGERTREGNDLYHEFIESGVNKKGGGEGSKAALVYGQMNEPPGARARVGLTGLTVAEYFRDQGQDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGALQERITTTTKGSITSVQAIYVPADDLTDPAPATSFAHLDATTTLNRAIAEKGIYPAVDPLDSTSRMLDPMVVGEEHYAVARQVQSILQRYKSLQDIIAILGMDELSEEDKQTVARARKIERFLSQPFFVAEVFTGAPGKLVDLADTIKGFKGLCNGDYDHLPEAAFYMVGGIEEAVEKAQRLAAEAA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LADIS_STRCL
Sequence: MPVDVGTLPPPAPREAVSAAAHLLASVDGDPWGRTSPTVYETARVHAWAPHLPGRDRRVTWLLDQQRAGGLWGDGPPAYQVLPTLAAVTALLAELDRHPEAGHSSLGGRLAAAVAAGLDTLHGLSHHDPLPDTAAVELLVPGLITEVNDRLDAIDPEAAHPALAPVPHGRRLTAVHGIPALPRHRLAERLARFARLPVKLHHCFEALAPVCPPGLVPARPDHLLGSSSAATAAWLATATAAPGAPGLDRLLRSTAARYGGLFPETARITVFERLWVLTTLHRAGLLATFEPLARRWVSALAAPGGVPGVPGFEPDADDTAVTLHLATELGVPYRPEVLDPFRTGDHFACYLGEDTGSVSTNAHVLLALGTWTRHHPDTADHGNTIRLLGRWLVERQHGDGHWDDKWHASPYYATAKVTAALSRHGGPEAADALRRAARWVRETRRTDGSWGIWGGTAEETAYAAQILLDAPEPPTDVLGCAHAHLTARADDDGPPPALWHDKTLFAPDAIVRAEVLSTLRRLDRRLPAPAPVPPGFDAARTGPAD
What is the function of this protein?
Involved in the biosynthesis of the labdane-type bicyclic diterpene labda-7,13(16),14-triene.  Catalyzes the conversion of geranylgeranyl diphosphate (GGDP) into labda-7,13(E)-dienyl diphosphate.
What are the official names of this protein?
Labda-7,13-dienyl diphosphate synthase, Type-B diterpene synthase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: ACSD_MOOTH
Sequence: MAVQILRDRSRAAVQKVVLGATKDQGGTRSHTIVVGGDAALPFHHFEGEIVNRPVIGMEVQDIVPDWPDVLKDPFTDVINEPGRWAQKCVAEYGADLIYLKLDGADPEGANHSVDQCVATVKEVLQAVGVPLVVVGCGDVEKDHEVLEAVAEAAAGENLLLGNAEQENYKSLTAACMVHKHNIIARSPLDINICKQLNILINEMNLPLDHIVIDPSIGGLGYGIEYSFSIMERIRLGALQGDKMLSMPVICTVGYEAWRAKEASAPVSEYPGWGKETERGILWEAVTATALLQAGAHILLMRHPEAVARVKENIDQLMVSNAY
What is the function of this protein?
Acts as a methyl group carrier in the anaerobic acetyl-CoA pathway (Wood-Ljungdahl pathway) of carbon monoxide and carbon dioxide fixation.
What are the official names of this protein?
Corrinoid/iron-sulfur protein small subunit, C/Fe-SP small subunit, CFeSP small subunit.
Protein: P2C05_ORYSJ
Sequence: MALLSPRVPRLPLASASAAGAGLRCCVSGGRAGSAAWCHASAAGSVASSSSELEAIRWGTAKLQGARDEMEDEVVLRPGSLLDGFSFAAVFDGHAGFSAVEFLRDELYKECAAALDGGAVLSTKNLDAITDSIQRAFATVDANLSTWLEQMDKEDESGATATAMFLRNDVLVVSHIGDSCLQVVSRGGRPQAVTNFHRPYGNKKASLEEVKRIRAAGGWIVDGRICGEISVSRAFGDIRFKTRKNEMLVKGVKEGRWTEKFISRINFKGDLIVSSPDVSLVELGPDVEFVLLATDGLWDYIKSSEAVALVRDQLRQHGDVQVACEALGQIALDRRSQDNISIVIADLGRTNWKELPAQRPNLFLELTQAVATVGAVSLGIYISSLLALQ
What are the official names of this protein?
Probable protein phosphatase 2C 5, OsPP2C05.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MIAA_ECO8A
Sequence: MSDISKASLPKAIFLMGPTASGKTALAIELRKILPVELISVDSALIYKGMDIGTAKPNAEELLAAPHRLLDIRDPSQAYSAADFRRDALAEMADITAAGRIPLLVGGTMLYFKALLEGLSPLPSADPEVRARIEQQAAEQGWESLHRQLQEVDPVAAARIHPNDPQRLSRALEVFFISGKTLTELTQTSGDALPYQVHQFAIAPASRELLHQRIEQRFHQMLASGFEAEVRALFARGDLHTDLPSIRCVGYRQMWSYLEGEISYDEMVYRGVCATRQLAKRQITWLRGWEGVHWLDSEKPEQARDEVLQVVGAIAG
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: M3K20_CAEEL
Sequence: MSTPTSNESTSSSSNNSDQRVLFPDIQRDDIQVGDHIGVGTFGAVFSGNWTLPDGSQRTIALKKVFVLEKEAEILSKIRHKNIIQFYGICKATGNDFFIVTEYAEKGSLYDFIHSEESQSFASSSGGNSFDVVVKWASQIASGIQYLHYDAVDTIIHRDLKSKNVVLDKNLVCKICDFGTSKDLTHSCTAPSWGGTAAWMSPEMILQSEGLTTATDVWSYGVVLWEILSKEVPYKDYSEFRIFTMITQSGITLAIPPSCPAPLKQLMSNCWKMTPKDRANMRQIQGELNRLAGNQKVMDECEKFMGLEDWKTEIEKQEKNVEKMRKDLEKRREQLEIREKALKQRMKVEQAVLDSARHPPEDVHQWSEHHTSHWVETVLGRVANDKKFLDRVNAAVFRNRITGARLLGMTQNDLEHLGVHKVGSRIELMKMIRKLADTQKALHNFPTLEQAKRIEMTLKTEKEAAGQLANDVDIVIIVGMYVRKMNATRRKFKFYADSDWIDDTDIPAKSKSKHASSLIKTVCFSVLDENTKKPINEPACSISSGMTTNPDWITVDTEDDVKIRVIVSVYYADIVTQPRNTEVIKVVTSLEESKILEERHVHLRLRRSSSSASISTPSPVIAPVYHPFGHLNNGFHHTTSSPQLRGFWHRKQTGMNRHGLTETELSSLQEQLRTPSPDKKVVDENVIIHVPKLTRRRRTTTTNSEDTEKSDTNNKTPESQARRVHVHGGKDKWNWKKGKSRPKFT
What is the function of this protein?
Stress-activated component of a protein kinase signal transduction cascade that promotes programmed cell death in response to ribotoxic stress (PubMed:32289254).  Acts as the proximal sensor of ribotoxic stress: directly binds to the ribosome, thereby acting as a sentinel for colliding ribosomes (By similarity).  Upon ribosome collisions, activates the stress-activated protein kinase signal transduction cascade, leading to programmed cell death (By similarity).  Acts by catalyzing phosphorylation of MAP kinase kinases, leading to activation of the JNK and MAP kinase p38 pathways (PubMed:32289254).
What are the official names of this protein?
Mitogen-activated protein kinase kinase kinase zak-1, Mitogen-activated protein kinase kinase kinase 20 homolog.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
Protein: CXB4_HUMAN
Sequence: MNWAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGCPNVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREERERKHHLKHGPNAPSLYDNLSKKRGGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDYDMPRVVACSVEPCPHTVDCYISRPTEKKVFTYFMVTTAAICILLNLSEVFYLVGKRCMEIFGPRHRRPRCRECLPDTCPPYVLSQGGHPEDGNSVLMKAGSAPVDAGGYP
What is the function of this protein?
Structural component of gap junctions (By similarity).  Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells.  They are formed by the docking of two hexameric hemichannels, one from each cell membrane (By similarity).  Small molecules and ions diffuse from one cell to a neighboring cell via the central pore (By similarity).
What are the official names of this protein?
Gap junction beta-4 protein, Connexin-30.3, Cx30.3.
What is the protein family that this protein belongs to?
Belongs to the connexin family. Beta-type (group I) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. Note=Colocalizes with GJB2 at gap junction plaques in the cochlea.
Protein: SMD1_HUMAN
Sequence: MKLVRFLMKLSHETVTIELKNGTQVHGTITGVDVSMNTHLKAVKMTLKNREPVQLETLSIRGNNIRYFILPDSLPLDTLLVDVEPKVKSKKREAVAGRGRGRGRGRGRGRGRGRGGPRR
What is the function of this protein?
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (PubMed:11991638, PubMed:18984161, PubMed:19325628, PubMed:23333303, PubMed:25555158, PubMed:26912367, PubMed:28502770, PubMed:28781166, PubMed:28076346).  Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (PubMed:11991638, PubMed:26912367, PubMed:28502770, PubMed:28781166, PubMed:28076346).  As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (PubMed:15146077).  May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA (Probable).
What are the official names of this protein?
Small nuclear ribonucleoprotein Sm D1, Sm-D1, Sm-D autoantigen, snRNP core protein D1.
What is the protein family that this protein belongs to?
Belongs to the snRNP core protein family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Note=SMN- mediated assembly into core snRNPs occurs in the cytosol before SMN- mediated transport to the nucleus to be included in spliceosomes.
Protein: URE3_SACD2
Sequence: MELNPREKDKLLLFTAALLAERRKARGVKLNYPEAIALISAEVMEGARDGKTVAELMEAGRQVLRVEDVMDGIADMIHEVQVEATFPDGTKLVTVHNPIV
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBFA_RICB8
Sequence: MKKLTSENSHRQQKVASIINEALIEILHRGKMLDPRLYDCPLTITKIIVTADLKIANCYFLPFNTKLTPQEITESLNNSKNAIRNFVTGKINMKYSPDIRFHYDHGFDNALKVEQLLKDTNNI
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDE_SALPB
Sequence: MSDIALTVSVLALVAVVGLWIGNIKVRGVGFGIGGVLFGGIIVGHFVDQAGVTLSGDMLHFIQEFGLILFVYTIGIQVGPGFFASLRVSGLRLNLFAVLIVIMGGLVTAILHKIFAIPLPVVLGIFSGAVTNTPALGAGQQILRDLGTPVDLVDQMGMSYAMAYPFGICGILLTMWLMRLIFRVNVEAEAQKHESSLANGHSLIQTMNIRVENPNLNNMAIQDVPILNSDKIICSRLKRDDTLMVPSPGTIIQAGDLLHLVGQSTDLHNAQLVIGKEVDTSLSTRGTDLRVERVVVTNEKVLGKRIRDLHFKERYDVVISRLNRAGVELVASSDASLQFGDILNLVGRPASIDAVANVVGNAQQKLQQVQMLPVFIGIGLGVLLGSIPLFVPGFPVALKLGLAGGPLIMALILGRIGSIGKLYWFMPPSANLALRELGIVLFLAVVGLKSGGDFVDTLTQGEGLSWIGYGIFITAIPLITVGLLARIFAKMNYLTLCGMLAGSMTDPPALAFANNLHATSGAAALSYATVYPLVMFLRIITPQLLAVIFWGMG
What are the official names of this protein?
Putative transport protein YidE.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family. YidE subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ZIP2_ORYSJ
Sequence: MAGGRGARASLHLHLAWLCAFATTAWAHGGGGGGGDSDADADGGGEGKPDLRARGLVAAKLWCLAVVFAGTLAGGVSPYFMRWNDAFLALGTQFAGGVFLGTAMMHFLADANETFADLLPGTAYPFAFMLACAGYVLTMLADCAISFVVARGGGRTEPAAAAGAGLEEGKLSSTNGNASDPPAADAAAQDHSVASMLRNASTLGDSVLLIAALCFHSVFEGIAIGVAETKADAWKALWTISLHKIFAAIAMGIALLRMLPDRPFLSCFGYAFAFAVSSPVGVGIGIVIDATTQGRVADWIFAVSMGLATGIFIYVSINHLLSKGYTPLRPVAADTPAGRLLAVVLGVAVIAVVMIWDT
What is the function of this protein?
Zinc transporter that may be involved in zinc uptake from the rhizosphere.
What are the official names of this protein?
Zinc transporter 2, ZRT/IRT-like protein 2, OsZIP2.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ACCA_ENTFA
Sequence: MEKKTANDVVTLARAQDRLTTLEYIEAIFEDFLEFHGDRYFADDLAVVGGVATLQGKPVTVVGIQKGRNLPENIERNFGSPNPEGYRKALRLMKQAEKFNRPVITFVNTAGAYCGIGAEERGEGEAIAQNLLEMSDLKVPIISVIIGEGGSGGALALAVADEVWMLEHTIYAVLSPEGFASILWKDGSRAKEAAELMKITATELKELAIVDKVIPEVMNGQPLEQAKINRMLQKAFISKLTELAKLDTETLLEKRYQRFRKY
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_ERWT9
Sequence: MKPAARRRARECAVQALYSWQISKNDIADVEYQFLAEQDVKDVDITYFRELVGGVATNSAYLDGLMKPYLSRQLEELGQVEKAILRISLFELSKRSDVPYKVAINEGIELAKVFGAEDSHKFVNGVLDKAAPQIRPNRK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.