PharMolix/UniProtQA huggingface dataset:
Protein: G3P_KITAU
Sequence: MTRIAINGFGRIGRNVLRALLERDSDLDVVAVNDLTEPATLARLLAYDTTSGRLGRPVTVEGNVLVVDGRRITVTAEREPANLPWAELGVDIVLEATGRFTSAKAARAHLDAGAKKVLVSAPADGADITLAFGVNTDAYDPDLHTIVSNASCTTNALAPLAKVLDDLAGIEHGFMTTVHAYTQEQNLQDGPHRDPRRARAAAVNIVPTTTGAAKAIGLVLPNLDGKLSGDSIRVPVPVGSIVELNTTVARDVTRDEVLDAYRAAAQGPLAGVLEYSEDPLVSSDITGNPASSIFDSELTRVDGRHIKVVAWYDNEWGFSNRVIDTLQLLAAR
What is the function of this protein?
Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD.  The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH.  The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, NAD-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDGB_TREDE
Sequence: MAFAASQQLNRYYNLYKNIDVTFSKEVVSTLNFEPKQVFVRCSGGQWPCIINSASMTKAKIICGKKSGFLARLRSGITSVNIRFAFFDTEGKDSLSFFVAAKLVGISSYEAGNQDLVLITFEYTQRAPDDLIEKLGILLEANINSQKRRNERVVITPEISRKIGLVEKGTVVYIDAVPRRCLIRDLSFSGAKILLVGIANFLINKEVILRFAFDDPQSVFGIKGKTVRTEPVEGRKDLVALAVQYYPKNIPMMYKMYLNKYFSVVRKPASDGFGDDFLEDVAPASSFTPVSSPIGTNTAPLTPPPADSAPEQIS
What is the function of this protein?
Cyclic-di-GMP binding protein that plays important roles in motility, chemotaxis, biofilm formation and virulence.
What are the official names of this protein?
Cyclic di-GMP binding protein TDE_0214.
Protein: DUS3_KLULA
Sequence: MDPSQPQVKRPASSDEQPSAKKTDTATSKGIAHLKPEFILFNDQNGSSRPMAGEYNDEEESTSSRLESQPANQIKGKKQNSKKKRGQNKNRDNRQVREQHALCSKFVTNVDATCSFDTKCRYVHDVREYLSKKAPEIKTEFFPICPVWQSLGHCPMGYKCCFLSSHCNMETLELKDLYEVDERKKLYEANHEINHIDGERKYDLIKRRFSFTKSDYILEIIDAMQQENRDLMNTSKGSETTTDANAGEDANDEKVSFQATEKQNQLTEKRERQRELYLKYHDTRFFAQEKRKLDLHHKKIVSPLTTVGNLPYRRLMRKLGADVTYSEMALAVPLIQGTNSEWALPKAHCSEFPGFGVQIACSKTWQAAKAAEALAANVTGVSEINLNSGCPIDLLYRQGSGSALLDNPARMIRCLNGMNYVSNDIPVTVKIRTGTREGHPIALSITKRLVLETDVAAITLHGRTRQQRYTKSADWDYVGEVANAVRTYEAERQENKNLRDGQKIQFVGNGDCNNWEDWYKHLENKNMDSVMVARGALIKPWIFEEVDAQQYMDKSSKERLEILKDYCKFAMDHWGTDQYGISQCRRFFCEFMSFFHRYVPMGICERYPVLLNERPPNWKGRDDLETLLGSTDSNDWLKLSEMFFGKVNDEFVFTPKHKSNSFATN
What is the function of this protein?
Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.  Specifically modifies U47 in cytoplasmic tRNAs (By similarity).  Catalyzes the synthesis of dihydrouridine in some mRNAs, thereby affecting their translation (By similarity).
What are the official names of this protein?
tRNA-dihydrouridine(47) synthase [NAD(P)(+)], mRNA-dihydrouridine synthase DUS3, tRNA-dihydrouridine synthase 3.
What is the protein family that this protein belongs to?
Belongs to the Dus family. Dus3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL1_STRPJ
Sequence: MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEVAYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVAKINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGKITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKVKPATAKGTYVTNLTITTTQGVGIKVDVNSL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: NUOB2_GLUDA
Sequence: MSAANATGEGQDAIAWNREMLPPGPEQDAVIKGITGEITEKGFVVASLDKLVNWGRTGSLWPMSFGLACCAVEMIHAYMPRYDLDRMGIIPRGSPRQSDVMIVAGTLTNKMAPALRRVYDQMAEPRWVISMGSCANGGGYYHYSYSVVRGCDRIVPVDVYVPGCPPTAEALIYGIFQLQKKIRRTGTILRG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B 2, NADH dehydrogenase I subunit B 2, NDH-1 subunit B 2.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TYSY_AGABI
Sequence: MHDEDQYLHLIRRVLDTGDLRPDRTGTGTISLFAPPNLRFSLRESTVPLLTTKRTFLRGIVEELLWFTNGLTDSKILSDKGVKIWDGNGSKAFLESRGLGHRREGDLGPVYGFQWRHFGAEYEDCDADYAGKGVDQLRECIRKIKENPTDRRIILSAWNPKDIPSMALPPCHMLCQFYVHLPADTAKPELSCLMFQRSADLGLGIPFNIASYALLTHMIAHVTGTTARELIIQLGDAHVYRDHVEALEVQLQREPRPFPKLRWARDGITDIEDFEYSDFVIEGYNPHPSIAMKMSV
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family.
Protein: PUR5_BACP2
Sequence: MSEAYKNAGVDIEAGYEAVKRMKTHVERTKRAGVMGALGGFGGMFDLSELPYKKPVLVSGTDGVGTKLKLAFLMDKHDTIGVDAVAMCVNDVLAQGAEPLFFLDYLAVGKADPVKIESIVKGVADGCEQSGSALVGGETAEMPGLYTEEEYDIAGFSVGVVEKDEIVTGNSIKEGHLLIGLSSSGIHSNGYSLVRKVLLEDAGLDLHQTYEPFKRPLGEELLEPTKIYVKPVLKQVKAGKVDGMAHVTGGGFIENLPRMLPEGLGVEIDNGSWPVPPIFSFIQEKGQLKAEEMFNVFNMGIGFVLAVKEDDLVDVIRELEQDGEKAFLIGRVQKGEGVTFGGGSLS
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GAG_HTL1M
Sequence: MGQIFSRSASPIPRPPRGLAAHHWLNFLQAAYRLEPGPSSYDFHQLKKFLKIALETPVWICPINYSLLASLLPKGYPGRVNEILHILIQTQAQIPSRPAPPPPSSPTHDPPDSDPQIPPPYVEPTAPQVLPVMHPHGAPPNHRPWQMKDLQAIKQEVSQAAPGSPQFMQTIRLAVQQFDPTAKDLQDLLQYLCSSLVASLHHQQLDSLISEAETRGITSYNPLAGPLRVQANNPQQQGLRREYQQLWLAAFAALPGSAKDPSWASILQGLEEPYHAFVERLNIALDNGLPEGTPKDPILRSLAYSNANKECQKLLQARGHTNSPLGDMLRACQTWTPKDKTKVLVVQPKKPPPNQPCFRCGKAGHWSRDCTQPRPPPGPCPLCQDPTHWKRDCPRLKPTIPEPEPEEDALLLDLPADIPHPKNSIGGEV
What is the function of this protein?
Binds strongly to viral nucleic acids and promote their aggregation.  Also destabilizes the nucleic acids duplexes via highly structured zinc-binding motifs.
What are the official names of this protein?
Gag polyprotein, Pr53Gag.
What are the subcellular locations of this protein?
[Matrix protein p19]: Virion. SUBCELLULAR LOCATION: [Capsid protein p24]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p15-gag]: Virion.
Protein: ORF9B_BCRP3
Sequence: MDPKTSVVLPALHLVDPQIQLTTTRMEDAVVHGQNNADLKVYPIILRLGSQLSLSMVRRNLDSLEVRVFQSTPIVVKMTKLATTEELPDEFVVVTAK
What are the official names of this protein?
Protein 9b, Accessory protein 9b, ORF-9b.
What is the protein family that this protein belongs to?
Belongs to the coronavirus group 2 protein 9b family.
What are the subcellular locations of this protein?
Host cytoplasmic vesicle membrane; Peripheral membrane protein. Host cytoplasm. Note=Binds non-covalently to intracellular lipid bilayers.
Protein: RNC_PSEU2
Sequence: MSVSLSRLERQLGYTFKDQELMVLALTHRSFAGRNNERLEFLGDAILNFVAGEALFERFPQAREGQLSRLRARLVKGETLALLARGFDLGEYLRLGSGELKSGGFRRESILADALEALIGAIYLDAGMEAARERVLAWLTTEFDSLTLVDTNKDPKTRLQEFLQSRACELPRYEVVDIQGEPHCRTFFVECEINLLNEKSRGQGVSRRIAEQVAAAAALIALGVENGHE
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T150B_MOUSE
Sequence: MWNYLSLLPVILFLWAIAGIWIVFAIAVVNGSVDLNEGFPFISICGSYAPQSCIFGQVLNIGAALTVWICIVRHHQLRDWGVKTWQNQLILWSGILCALGTSIVGNFQDKNQKPTHLAGAFLAFILGNLYFWLQFFLSWWVKGLPQPGPHWIKSLRLSLCSLSTILIVAMIVLHALHMRSASAICEWVVAMLLFMLFGFFAVDFSILRGCTLHLHPRLDSSLPQAPSGSPNIQMAQVL
What is the function of this protein?
Modulator of macroautophagy that causes accumulation of autophagosomes under basal conditions and enhances autophagic flux (By similarity).  Represses cell death and promotes long-term clonogenic survival of cells grown in the absence of glucose in a macroautophagy-independent manner (By similarity).  May have some role in extracellular matrix engulfment or growth factor receptor recycling, both of which can modulate cell survival (By similarity).
What are the official names of this protein?
Modulator of macroautophagy TMEM150B, Transmembrane protein 150B.
What is the protein family that this protein belongs to?
Belongs to the DRAM/TMEM150 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein. Note=Localizes mainly at the plasma membrane where it concentrates at actin-rich focal adhesions (By similarity).
Protein: AMPP2_ARTBC
Sequence: MASYSVTVSVAGTSINKYPAGSAGFDLAMADSYDPGKQHARRVAAYLPKQQGLIYLPGQQTVLSEDSDQARPFKQRRYFFYVTGVVEPDCHVTYDIAEDKLTLYVPDFDFKRTIWTGPTLGKDEASQRYDVDRVEYFSALEGDVLRWSQANPSLPIYILHPDQRPVTPLTVAYLYESKSLKHAMDACRVIKDEHEIQLIQRANRVSGAAHRSILANLHHFKNEAQIAGLFIDVCLSLRSKGTAYQTIAGSGSNGATLHYTRNNEPLAGRQMVVLDAGAEWSCYASDVTRSFPIPSSVSGGRDWPSREAEQIYAIVQRMQEECISRVKEGTLFFSIHQHAHAIALEELLKLGILRIPQGSTKADLIKAEVTALFFPHGLGHHLGLEVHDVSPDSGTIPVELAIEREKGLMSVTEHRPPCTLSAPPLASGMVITVEPGLYFNRLAIDQARAERDEPNSKGRFVNFDVVERYVDVGGVRIEDDVLVTKDGNKNLTDAPKGKEMLDLIYGR
What is the function of this protein?
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.
What are the official names of this protein?
Probable Xaa-Pro aminopeptidase ARB_01886, Aminoacylproline aminopeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: NADK_MAGMM
Sequence: MNSIGLVTKLSDPMAIRATSELTEWLNKQHRRVTVTAEAAKAANISPKLAAIKPLEDIGEGQDLVIVLGGDGTFIGAARDVLRWKVPVLGVNMGRLGFLTEVSYDEMYDNLKEVFAGHYNVEDRMMLTAFIRRESGEVLSHHVLNDVVAHKGHLARMMEFQVSINGQHVFTSRADGLIVATPTGSTGYSLSAGGPIIHPRLDTIIINPICPHTLSNRPIAVPGDGQISFRLTQNEPDRLLTLDGQTGVPLLDGDEIVIRKSDRSLRVIHSPDRNYYDILRKKLHWAETVGTKRDLSLRPADDR
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FEND_DROME
Sequence: MFHSLVLMACALAALSVAQGAGSARSKSLPLSLSLSVSVSSSLASASSPGAAADPTAAFTVTATAPTPASAPFAGKQLNRCRQSCYQQLSKDWHYCKDSVDCTNCCQKLVAPFELRILKAQRQESLVLTDIGWDEMIANASRQCLITWEVSGGGLIGNLLTDTARAELSLWPDTVYNIQVKCKHKLTGLMRRSIKLNVDTSQLVGTTTTTTTSKSSIQRQHLEQPVDHTDALEHSQHIRIPRPTDRVYIISALPTPSELGGVVYPAFGALAFFLALLVMFLFLRPQRKRFPLDADSADTATLIGRSSSSSRNSMDASTLHV
What is the function of this protein?
Involved in the normal targeting of ventral muscle, muscle 12, by motoneurons.  May function as an axon guidance molecule involved in neuromuscular specificity.
What are the official names of this protein?
Transmembrane protein fend, Protein forked end.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: YFCJ_SHIFL
Sequence: MTAVSQTETRSSASFSLFRISFAVFLTYMTVGLPLPVIPLFVHHDLGYGNTMVGIAVGIQFLATVLTRGYAGRLADQYGAKRSALQGMLACGLAGGALLLAAILPVSAPFKFALLVIGRLILGFGESQLLTGALTWGLGIVGPKHSGKVMSWNGMAIYGALAVGAPLGLLIHSHYGFAALAITTMVLPLLAWACNGTVRKVPALAGERPSLWSVVGLIWKPGLGLALQGVGFAVIGTFVSLYFASKGWAMAGFTLTAFGGAFVVMRVMFGWMPDRFGGVKVAIVSLLVETVGLLLLWQAPGAWVALAGAALTGAGCSLIFPALGVEVVKRVPSQVRGTALGGYAAFQDIALGVSGPLAGMLATTFGYSSVFLAGAISAVLGIIVTILSFRRG
What are the official names of this protein?
Uncharacterized MFS-type transporter YfcJ.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. YfcJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS15_DESRM
Sequence: MALSPEKKNEIIENFKTHEGDTGSPEVQIALLTERINQLTMHLKSFKKDHHSRRGLLKMVGQRRALLNYLRDRNFDRYRTILEKLGLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: RPOT3_ARATH
Sequence: MASAAAASPSLSLNPTSHFQHQTSLVTWLKPPPSSALFRRKTLPFFERHSLPISASSSSSSSSSTSLSVHEKPISNSVHFHGNLIESFENQDSSYAGTIKGASLIEELENPVERNGLSGRRRLFMQDPPWISALFLKGLSKMVDQTLKIERKDIDKRKFDSLRRRQVKEETEAWERMVDEYRDLEKEMCEKNLAPNLPYVKHMFLGWFQPLKDVIEREQKLQKNKSKKVRAAYAPHIELLPADKMAVIVMHKMMGLVMSGHEDGCIQVVQAAVSIGIAIEQEVRIHNFLKRTRKNNAGDSQEELKEKQLLRKRVNSLIRRKRIIDALKVVKSEGTKPWGRATQAKLGSRLLELLIEAAYVQPPLTQSGDSIPEFRPAFRHRFKTVTKYPGSKLVRRYGVIECDSLLLAGLDKSAKHMLIPYVPMLVPPKRWKGYDKGGYLFLPSYIMRTHGSKKQQDALKDISHKTAHRVFEALDTLGNTKWRVNRNILDVVERLWADGGNIAGLVNREDVPIPEKPSSEDPEELQSWKWSARKANKINRERHSLRCDVELKLSVARKMKDEEGFYYPHNLDFRGRAYPMHPHLNHLSSDLCRGTLEFAEGRPLGKSGLHWLKIHLANLYAGGVEKLSHDARLAFVENHLDDIMDSAENPIHGKRWWLKAEDPFQCLAACVILTQALKSPSPYSVISHLPIHQDGSCNGLQHYAALGRDSFEAAAVNLVAGEKPADVYSEISRRVHEIMKKDSSKDPESNPTAALAKILITQVDRKLVKQTVMTSVYGVTYVGAREQIKRRLEEKGVITDERMLFAAACYSAKVTLAALGEIFEAARAIMSWLGDCAKIIASDNHPVRWITPLGLPVVQPYCRSERHLIRTSLQVLALQREGNTVDVRKQRTAFPPNFVHSLDGTHMMMTAVACREAGLNFAGVHDSYWTHACDVDTMNRILREKFVELYNTPILEDLLQSFQESYPNLVFPPVPKRGDFDLKEVLKSQYFFN
What is the function of this protein?
Nuclear-encoded DNA-dependent RNA polymerase that catalyzes the transcription of DNA into RNA in chloroplasts using the four ribonucleoside triphosphates as substrates (Probable).  Required for chloroplast development and leaf mesophyll cell proliferation (PubMed:16698900).
What are the official names of this protein?
DNA-directed RNA polymerase 3, chloroplastic, Protein SCABRA 3.
What is the protein family that this protein belongs to?
Belongs to the phage and mitochondrial RNA polymerase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YC55L_SYNY3
Sequence: MSESPLTIVIVDEDPVFRLGLITVLGRETGVQVLGEGETLDDLRQQLETLAPSILLIDPQFPRRSQSAWPLLRQLSSAYPQVKICLLTASLEYDQLLAAKTQGIAAYFPKGTAIADLVTGLKQVHFGQTCWPSLQTVNAPPLSLWEKLIWPLFRDGLGQIEQSLQQVQKSLQVPSLSDFDRLFWRGRERELKFAQWLVRNLLPQRLKTWHKATNILTATTTVLPPSPPSPRRSGVRTITLRPPSNLTALGQILQQMPLQVENLTAIPLELDILQPLKRQELLSLGQQQLETTINELKALRITPAQLPENCLSIVAEMWRSLSLTFFGKYCQPKSEFSLEQIQSLLEVYQPIICREKLVKIPFVVPLFHHLLFGEPLVVNQKAYPLGSTEAQQYSDLYAQNLVIQLANSTMVFILNYFADHEAIKLALYEYSMLSSRQVARFRNDLAWYYQFSRYWLNPKQIFESQHTLLYLTPAGIVTTQVYAPRQQELTQLRAVPWFVTIVLECRDALSPRVRSVIEFVGNGLVFLLTQVVGRAIGLVGKGIIQGIGNTWQESRSQQKRSN
What are the official names of this protein?
Ycf55-like protein.
What is the protein family that this protein belongs to?
Belongs to the ycf55 family.
Protein: RS8_LEGPA
Sequence: MSMHDPIADMLTRIRNGQQAKHQQVTLVSSKLKEEIARVLKEEGYIQDFFTETLPNGLKSITLKLKYYHGRPVIEFIKRISRPGLRVYKSYKDLHSIPGFGVAILSTSKGIMTHVSAKVKGVGGEVICEVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: FAB1D_ARATH
Sequence: MTPSNSLSSSERSLSGECSVDGNSCDRGIEDECSSHSSQEDVELTKEVKVDRLERKSKSMPSDILDILDEKSKENSVENVQFLSDREDDSDDVPVWEPPEPENPEDEVDGVFADDDDDCCDGSKWNKASLLGELSDESSEKRKVYEENRRVMLEEADSKFKFIVSQLIKSAGFSIEESGYWFEIVARLCWEAASMLKPAIDGKSVDPTEYIKVKCIATGSCVDSEVFKGLVFKKHAALKHMATKYEHPRIMLVEGVLGHPISGFSSLQSVNQDNEYLLKYVKPVVDIIEASKPDVMLVEKSVSRDIQKTILDKGVTLVFDMKLHRLQRISRCIGSPILSVDSLSSQKLKHCDSFRIEKIVEEHNAAGESDKKPTKTLMFLEGCPTRLGCTILLKGCHSERLKKVKEVVQYSFILAYHLMLEASFLADRHTMFSTIFAKEATSCVVEIENFSPSPSPRESPSEAVDIPVSNGFDEQTIQINGEADGEKVGTWESDGDHVFSHEPYNPVIFTGFSSLSARLSKYLGFVQNPESVPVSVDTDVSTTSNLDSIRESEEDTAEKNEDKQPLLLDPELPVNSSSDDGDNKSQTENDIESTLESQSILVLVSKRNALRGIMCDQRHFSHIKFYKHFDVPLEKFLRDMFNQRNLCQTCVEFPEAHLYYYAHQNKQLTIQIKRIPVAKGLAGEAKGKIWMWSRCGKCKTKNASRKSTKRVLISTAARSLSFGKFLELSFSQQTFLNRSSSCGHSFDSDFLHFFGLGSMVAMLSYSQVASYTVSLPPMKLESSILIKAGWLEKEFQTVFTKGISLFEDAAGFLKRLRSQFTNSDLRYQRARKLLSNIEELLKHERCIFEENIKNSFDKAKTIDDVSHRLLRLNRMRWELLLQALIWNYRLQSLVLSDRLLPSSDETKIYEQGLKTVSEAGMTRYENDNKVSDSGSNGGIDTPLVEHKDIPIAGASVGDNDQMAESYVPEDNESQTLCSSSPDTTSPINNHFDTHLAVNVHSTNGQEADKSIPVTGESLDDEVSTSNGPHILGWDEWFWLPFEELRSKRIVDIEKEYLLKFEYVNNFTQENLQTVNQIITEESSRLRISLRDDDFIVSDYEDELSSLIACALAHLNNEESKKPLSRCIHGSLQGFLDNNQDSKQTDRDVSRFSSESTNRLETLPPPEVLVTFGSVKSVGKPKYSIVSLYADDFRDLRKRCCSSELDYIASLSRCKPWDAKGGKSKSVFAKTLDDRFIVKEIKKTEYESFVTFATEYFKYMKDSYDLGNQTCLAKVLGIHQVTVRQPKGGGKEIRHDLMVMENLSFSRKVTRQYDLKGALHARFTATSANGEDDVLLDQNFVNDMNKSPLYVSKTSKQNLQRAVYNDTSFLTSINVMDYSLLVGVDDENHELVCGIIDYLRQYTWDKQLETWVKSSLVVPKNVQPTVISPIDYKTRFRKFMKTHFLCVPDQWCDQGDS
What is the function of this protein?
The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).  Catalyzes the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 3,5-bisphosphate (By similarity).
What are the official names of this protein?
Putative 1-phosphatidylinositol-3-phosphate 5-kinase FAB1D, Phosphatidylinositol 3-phosphate 5-kinase, Phosphatidylinositol 3-phosphate 5-kinase type III, PIPkin-III, Type III PIP kinase, Protein FORMS APLOID AND BINUCLEATE CELLS 1D.
Protein: ENO_SHIB3
Sequence: MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: PACC_KLULA
Sequence: MSPIAHLLNASTGTDSGSHLRDIHGHHDSHDHGSEEQAVSPLSPRSYPSPRSNSSSSCEESQSSAGVLANIHTGPASPHGKACVASSPLSTTGMRSASTPSSSDEDTVHLHRCQWKGCSLEFTSPELLYHHLCQDHVGRKSQKNLQLNCQWGDCQTKTVKRDHITSHLRVHVQLKPFACSTCNKKFKRPQDLKKHLKVHNEELSLLKKKRGPKPSNKLGKISNDRSRAHQRFTLPSISLDKFIHEEVKTQQPVYSQQLAEKMAIVLLLPVNNNNATSPPSASSASSTAVSPNLVSHHMVLPYQTQQRPLVGHGAELRSAVGFFNNLSMDMSRNYANNNLPTANLGPNPVPAPQSYPLIPKLPSISARPNVGAPPPVLSVFNRFDTHQTSPSSSSSAFYPQHYSNNYSLHQRTALLDAEANEDIPEKDNVSLEESFTSLNLSSEEQDLELFYETYSTVKLVKDYLLCELMEELDEFKEEEEEQGFTSFDEFSDSKECVIEGRIPSNKISLSKYPQVVI
What is the function of this protein?
Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH.  At alkaline ambient pH, activates transcription of alkaline-expressed genes (including RIM101 itself) and represses transcription of acid-expressed genes (By similarity).
What are the official names of this protein?
pH-response transcription factor pacC/RIM101.
What is the protein family that this protein belongs to?
Belongs to the pacC/RIM101 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SYGA_SHIDS
Sequence: MQKFDTRTFQGLILTLQDYWARQGCTIVQPLDMEVGAGTSHPMTCLRALGPEPMAAAYVQPSRRPTDGRYGENPNRLQHYYQFQVVIKPSPDNIQELYLGSLKELGMDPTIHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECKPVTGEITYGLERLAMYIQGVDSVYDLVWSDGPLGKTTYGDVFHQNEVEQSTYNFEYADVDFLFTCFEQYEKEAQQLLALENPLPLPAYERILKAAHSFNLLDARKAISVTERQRYILRIRTLTKAVAEAYYASREALGFPMCNKDK
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_BUCAT
Sequence: MQNQRIRIRLKAFDHRLIDQSTTEIVETAKRTGAQVRGPIPLPTRKERFTILVSPHVNKDARDQYEIRTHKRLIDIVEPTEKTVDALMRLDLAAGVDVQISLG
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: DHRS2_HUMAN
Sequence: MLSAVARGYQGWFHPCARLSVRMSSTGIDRKGVLANRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLPYMENRRGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCVVPGIIKTDFSKVFHGNESLWKNFKEHHQLQRIGESEDCAGIVSFLCSPDASYVNGENIAVAGYSTRL
What is the function of this protein?
NADPH-dependent oxidoreductase which catalyzes the reduction of dicarbonyl compounds.  Displays reductase activity in vitro with 3,4-hexanedione, 2,3-heptanedione and 1-phenyl-1,2-propanedione as substrates (PubMed:16685466).  May function as a dicarbonyl reductase in the enzymatic inactivation of reactive carbonyls involved in covalent modification of cellular components (PubMed:16685466).  Also displays a minor hydroxysteroid dehydrogenase activity toward bile acids such as ursodeoxycholic acid (UDCA) and isoursodeoxycholic acid (isoUDCA), which makes it unlikely to control hormone levels (PubMed:16685466).  Doesn't show any activity in vitro with retinoids and sugars as substrates (PubMed:16685466).  Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21 (PubMed:20547751).  Reduces proliferation, migration and invasion of cancer cells and well as the production of ROS in cancer (PubMed:29106393).
What are the official names of this protein?
Dehydrogenase/reductase SDR family member 2, mitochondrial, Dicarbonyl reductase HEP27, Protein D, Short chain dehydrogenase/reductase family 25C member 1, Protein SDR25C1.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Nucleus. Note=A minor fraction of the protein is translocated from the mitochondria to the nucleus, after cleavage of the targeting signal.
Protein: ZN284_HUMAN
Sequence: MTMFKEAVTFKDVAVVFTEEELGLLDVSQRKLYRDVMLENFRNLLSVGHQLSHRDTFHFQREEKFWIMETATQREGNSGGKIQTELESVPETGPHEEWSCQQIWEQTASELTRPQDSISSSQFSTQGDVPSQVDAGLSIIHIGETPSEHGKCKKFFSDVSILDLHQQLHSGKISHTCNEYRKRFCYSSALCLHQKVHMGEKRYKCDVCSKAFSQNSQLQTHQRIHTGEKPFKCEQCGKSFSRRSGMYVHCKLHTGEKPHICEECGKAFIHNSQLREHQRIHTGEKPFKCYICGKSFHSRSNLNRHSMVHMQEKSFRCDTCSNSFGQRSALNSHCMDHTKEKLYKCEECGRSFTCRQDLCKHQMDHTGDKPYNCNVCGKGFRWSSCLSRHQRVHNGETTFKCDGCGKRFYMNSQGHSHQRAYREEELYKCQKCGKGYISKFNLDLHQRVHTGERPYNCKECGKSFRWASGILRHKRLHTGEKPFKCEECGKRFTENSKLRFHQRIHTGEKPYKCEECGKGFRWASTHLTHQRLHSREKLFQCEDCGKSSEHSSCLQDQQSDHSGEKTSKCEDCGKRYERRLNLDMILSLFLNDI
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 284.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.