PharMolix/UniProtQA huggingface dataset:
Protein: SCED_STAA3
Sequence: MKKTLLASSLAVGLGIVAGNAGHEAHASEADLNKASLAQMAQSNDQTLNQKPIEAGAYNYTFDYEGFTYHFESDGTHFAWNYHATGTNGADMSAQAPATNNVAPSAVQANQVQSQEVEAPQNAQTQQPQASTSNNSQVTATPTESKSSEGSSVNVNAHLKQIAQRESGGNIHAVNPTSGAAGKYQFLQSTWDSVAPAKYKGVSPANAPESVQDAAAVKLYNTGGAGHWVTA
What is the function of this protein?
Is able to cleave peptidoglycan and affects clumping and separation of bacterial cells.
What are the official names of this protein?
Probable transglycosylase SceD.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase family. SceD subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MURC_RHORT
Sequence: MRALPLDIGPLHFVGIGGIGMSGIAEVLHNLGYRVQGSDLSDNANVKRLRDLGIPIAIGHKAANLGDAQVVVISSAVKASNPEVMDARARFLPVVRRAEMLGELMRLKWSIAVAGTHGKTTTTSLVAQLLDAAGLDPTVINGGILNARGTNAYLGTGEWMVVEADESDGTFTKLPATISLVTNIDPEHLDFYGTFDKVREAFRAFIHNLPFYGFACMCIDHPEVQAMIPQLQDRKIITYGLSPQADIRGANVTLGPRGARFDVILTDRAGGGSRTIEGIRLPMYGRHNVLNALGAIGIAAEMGIDDAVIRDGLYHFEGVKRRFTRTGDAGGVTVIDDYGHHPVEIAAVLKAARDATEREVIAVVQPHRYSRLNSLFEDFCTCFNDADQVVVADVYAAGEQPIPGASKEALAEGLKVHGHKSVHVLTNEQALPELIARIAKPGDLVVCLGAGSISTWANALPKQLEAVQGRRRQTTLAGGAP
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPH_PSYCK
Sequence: MRIDNRELNQLRSISFERHYTKHAEGSVLVSFGDTKVLCTASVESGVPRWLKGKGKGWITAEYGMLPRATNTRNQREAARGKQSGRTQEIQRLIGRSLRAMIDLSKLGENTIYLDCDVLQADGGTRTASVTGAAIALIDALESIQKTKKLKADPLIGLVAAVSVGMKDGKAYLDLNYEEDASCDTDLNVVMTQKGEFIELQGTAEEKPFTRAQADDMLILAEKGIAELIAMQKTALGW
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: AMELY_BOVIN
Sequence: MGTWILFACLLGAAYSMPLPPHPGHPGYINFSYEVLTPLKWYQNMLRYPYPSYGYEPVGGWLHHQIIPVVSQQSPQNHALQPHHHNPMVPAQQPVVPQQPMMPVPGQHSMTPIQHHQPNLPLPAQQSFQPQPIQPQPHQPLQPQPPVHPIQRLPPQPPLPPIFPMQPLPPVLPDLPLEAWPATDKTKREEVD
What is the function of this protein?
Plays a role in the biomineralization of teeth.  Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development.  Thought to play a major role in the structural organization and mineralization of developing enamel.
What are the official names of this protein?
Amelogenin, Y isoform, Class II amelogenin.
What is the protein family that this protein belongs to?
Belongs to the amelogenin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: PURA_BURM9
Sequence: MSASAVNVTPGRNVVVVGTQWGDEGKGKIVDWLTDHAQGVVRFQGGHNAGHTLIIGGKKTILRLIPSGIMREGVACYIGNGVVLSPEALFKEIGELEEAGLSVRERLFISEATTLILPYHIAIDQAREARRGAGKIGTTGRGIGPAYEDKVGRRALRVQDLFDARTFADRLRENLDFHNFVLTQYLGGAAVDFQATLDTMLGYADRLKPMVTDVSRRLYEENHAGRNLLFEGAQGTLLDIDHGTYPFVTSSNCVAGAAAAGAGVGPQKLDYILGITKAYCTRVGSGPFPSELYDADNPSRQDQIGITLANVGKEFGSVTGRPRRTGWLDAAALRRSIQINGVSGLCMTKLDVLDGLDEVKLCVGYKIDGEDVDLLPRGAAEVARCEPVYETFGGWKESTVGIDSWDALPANARAYLTRVQEVAGVPIDMVSTGPDRDETILLRHPFKV
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF_AZOVD
Sequence: MAILTILEFPDPRLRTIAKPIETVDDGIRRLIDDMFETMYAAPGIGLAATQVNVHKRLVVMDLSEDKNEPRVFINPEFEALTEELEPYQEGCLSVPGFYENVDRPQKVRIRALDRDGQPFELVAEGLLAVCIQHECDHLNGKLFVDYLSTLKRDRIRKKLEKQHRQHG
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: QUEF_PROMS
Sequence: MSTAKLEDSTQRPLYGERIIEESKIICFDNPNKKRIYEISIQLPEFTCKCPFSGYPDFAKLNITYQPNLKVYELKSLKLYINNFRDIKISHEEVVNRIMDDLVNEGLPHWIHLNAAFNPRGNVSMQLDIFSGQKRN
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRP_DROME
Sequence: MGSNTESDAEKALGSRLDYDLMMAEEYILSDVEKNFILSCERGDLPGVKKILEEYQGTDKFNINCTDPMNRSALISAIENENFDLMVILLEHNIEVGDALLHAISEEYVEAVEELLQWEETNHKEGQPYSWEAVDRSKSTFTVDITPLILAAHRNNYEILKILLDRGATLPMPHDVKCGCDECVTSQMTDSLRHSQSRINAYRALSASSLIALSSRDPVLTAFQLSWELKRLQAMESEFRAEYTEMRQMVQDFGTSLLDHARTSMELEVMLNFNHEPSHDIWCLGQRQTLERLKLAIRYKQKTFVAHPNVQQLLAAIWYDGLPGFRRKQASQQLMDVVKLGCSFPIYSLKYILAPDSEGAKFMRKPFVKFITHSCSYMFFLMLLGAASLRVVQITFELLAFPWMLTMLEDWRKHERGSLPGPIELAIITYIMALIFEELKSLYSDGLFEYIMDLWNIVDYISNMFYVTWILCRATAWVIVHRDLWFRGIDPYFPREHWHPFDPMLLSEGAFAAGMVFSYLKLVHIFSINPHLGPLQVSLGRMIIDIIKFFFIYTLVLFAFGCGLNQLLWYYAELEKNKCYHLHPDVADFDDQEKACTIWRRFSNLFETSQSLFWASFGLVDLVSFDLAGIKSFTRFWALLMFGSYSVINIIVLLNMLIAMMSNSYQIISERADTEWKFARSQLWMSYFEDGGTIPPPFNLCPNMKMLRKTLGRKRPSRTKSFMRKSMERAQTLHDKVMKLLVRRYITAEQRRRDDYGITEDDIIEVRQDISSLRFELLEIFTNNNWDVPDIEKKSQGVARTTKGKVMERRILKDFQIGFVENLKQEMSESESGRDIFSSLAKVIGRKKTQKGDKDWNAIARKNTFASDPIGSKRSSMQRHSQRSLRRKIIEQANEGLQMNQTQLIEFNPNLGDVTRATRVAYVKFMRKKMAADEVSLADDEGAPNGEGEKKPLDASGSKKSITSGGTGGGASMLAAAALRASVKNVDEKSGADGKPGTMGKPTDDKKAGDDKDKQQPPKDSKPSAGGPKPGDQKPTPGAGAPKPQAAGTISKPGESQKKDAPAPPTKPGDTKPAAPKPGESAKPEAAAKKEESSKTEASKPAATNGAAKSAAPSAPSDAKPDSKLKPGAAGAPEATKATNGASKPDEKKSGPEEPKKAAGDSKPGDDAKDKDKKPGDDKDKKPGDDKDKKPADNNDKKPADDKDKKPGDDKDKKPGDDKDKKPSDDKDKKPADDKDKKPAAAPLKPAIKVGQSSAAAGGERGKSTVTGRMISGWL
What is the function of this protein?
A light-sensitive calcium channel that is required for inositide-mediated Ca(2+) entry in the retina during phospholipase C (PLC)-mediated phototransduction.  Ca(2+) influx may then feed back and inhibit PLC, thereby facilitating phosphatidylinositol 4,5 bisphosphate (PIP2) recycling.  Trp and trpl act together in the light response, though it is unclear whether as heteromultimers or as distinct units, and are activated by fatty acids and metabolic stress.  Also required for olfactory adaptation and may be involved in olfactory system development.
What are the official names of this protein?
Transient receptor potential protein.
What is the protein family that this protein belongs to?
Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Localized on plasma membrane loops found at the base of the rhabdomere, in close proximity to the calcium stores.
Protein: MATK_SYZSA
Sequence: MEEFQGYFELDRSRQHDFLYPLLFREYIYALAHDHGLNRSILFKNAGYDKKSSSIVVKRLITRMYQQNPLIFSANDSIQNPFFGHNKNLYSQIISEGFAVIVEIPFSLRLVSSLERKEIAKSHNLRSIHSIFPFLEDKFSHLDYVSDVLIPYHIHLEILVQTLRYWVKDASSLHLLRFFLHEYWNSLITPKKHITLFSKGNPRLFLFLYNSHICEYESIFLFLRNQSSHLRSTSSGIFFERIYFYVKIEHFAKVFFDNDFQCILWFFKDPFMHYVRYQGKSILASKDTPLLMNKWKYYLVTLWQYHFYAWFQPVRIDINQLCKYSLDFLGYRSSVRLNSSVVRSQMLENSFLINNAMKKFETIVPIIPLIGSLSKANFCNTLGHPISKPTRADSSDSDIIDRFLRICRNLSHYHSGSSKKKSLYRVKYILRLSCVKTLARKHKRTVRTFFKRLGSEFLEEFLTEEEVVLSLIFPRTYSTSRRLYRGPIWYLDITSINDLVNYENE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ACCD_BUXMI
Sequence: MEKWWFNSMLSNEELEHACGLSKSMESLGPIGNTSGGEDHIINNMDKNIHSWGDSGSSSCSNVYPLFGVRGIQGFISDDTFLVRDSNGDSYSIYFDIENKIFEIDNDHSFLSELESSFSSYQNNGSNSDNPYYDRYIYDTKYSWNNYINSCIDSYLRSEIRIDSYILSGSDNYSDSYIYSYICSECVNSSESSSIKTSTNGSDLNIRGRYNDLDLNKKYRHLWVQCENCYGLNYKKFFRSKMNICEQCGYHLKMSSSDRIELSIDTGTWDPMDEDMVSMDPIEFHSEEELYKDRINSYQRKTGLTEAVQTGIGQLNGIPIAIGVMDFQFMGGSMGSVVGEKITRLIEYATNRSLPVIIVCASGGARMQEGSLSLMQMAKISSASYNYQSNKKLFYVSILTSPTTGGVTASFGMLGDIIIAEPNAYIAFAGKRVIEQTLNKTVPDGSQTAEYLFHKGLFDPIVPRNLLKGVLSELFQLHGFFPLNSNSIK
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: IGAA_YERPE
Sequence: MSTIVLILALLLTSLIAVGLLWWLRFRRPHPITAALPFVKLTHRKLTPEERVSIENYLRNQQNKHGFNTQPAFDSHALAASTSSTPMLVLTPQSDNVYSVTRAITRYGVASDEPNKWRYYLDSIEVHLPSAWEQYITQDNDVELIQTQTIPLVISLNGHTLNNHQSENTYQPILPSVSKNASIRKEDSEHIELLNIRKETPEEYALHGPNGLKEACAICIALLLLFFALSGPTVTLPWLVIVAVSLTCWACWYLFRPLSEKDLREVHCLNGTPKRWGLFGESNQGQINNISLGIVDLIYPAHWGPYFVHDLGKKTHIDIYLNRQVVRQGAFLSLHDEMKMFPLQRWGKNLTLIVGSLLVLVLLLIYVPLGLPLKLSVAWLQGAQSQQVTSVAALDKMPLRIGDMLKAQGNGMCYVPPNIQNTRGFVFTPFDCSGIYWNTASPLPQPESETIEKAAALVETINKQLHPQGSDASVNPKLATAIEKSGMILLDDFSDIVLKTQALCSENTDCIRLKNALVNLGNAKNWSALVKRAQSGNLEGMNVLLRPISADVLENLINTAASSFVYRETHLATEALNSPPPGGFLITSDEGKQLVNHPAPTLPLFDYSALEQWRELQRLSALLLDTPFKAEGIITNITTDANGTRHIALHSEPDIVTLGRYLATSLLLLVLIFCLVVNMVLLIQRAMKNRRRMDNIQRYYDDCFNQTLTPPPFLR
What are the official names of this protein?
Putative membrane protein IgaA homolog.
What is the protein family that this protein belongs to?
Belongs to the IgaA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYT17_MOUSE
Sequence: MLEPLNEGLLSRISDVLLCGWTCQHCCQRCYESSCCQSSEDEVEILGPFPAQTPPWLMASRSNDKDGDSVHTASDVPLTPRTNSPDGRRSSSDTSKSTYSLTRRISSLDSRRPSSPLIDIKPVEFGVLSAKKESIQPSVLRRTYTPDDYFRKFEPRLYSLDSNLDDVDSLTDEEIMSKYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLLPDQKNSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKFSRHCVIGKVAVPLCEVDLVKGGHWWKALIPSSQNEVELGELLLSLNYLPSAGRLNVDIIRAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSNDFIGRIVIGQYSSGPSESNHWRRMLNTHRTAVEQWHSLRSRAECDRVSPASLEVT
What is the function of this protein?
Plays a role in dendrite formation by melanocytes.
What are the official names of this protein?
Synaptotagmin-17, Protein B/K, Synaptotagmin XVII, SytXVII.
What is the protein family that this protein belongs to?
Belongs to the synaptotagmin family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: DGTP_YERPG
Sequence: MSGIDFKQKISFQRPFSKPSSAEDEYEITRVFESDRGRIVNSAAIRRLQQKTQVFPLERNAAVRSRLTHSLEVQQVGRYIAKEILNRFKQDKKITAYGLDKLLDPFESIVEMACLMHDIGNPPFGHFGESAINDWFTKRMDPNGGSGSEPQSTDQCQVDVLKLCEGETELNILRSKIRHDLSQFEGNAQAIRLVHSLLKLNLTYAQVGCILKYTKPAYWSAPIPASHNYLMKKPGFYLAEENYVKELRRELNMEEFDRFPLTYIMEAADDISYCIADLEDAVEKNIFSVEQLYDHMSQEWGAVTPGDLFDKVVGAAFRQLGREQGRRSSEDQFFMYLRVNTVGKLVPHAAQRFIENLPAVFSGSFNQALLEDSSAACKLLQIFKRVAVKHVFNHPEVEQLELQGYRVISGLLDIYSPLLAMPETAFTQLVADDRHRKYPIETRLFHKLSIKHRLAYAESAERIRNLPSEQYEIYEYYYRARLIQDYISGMTDLYAYDEYRRLMAAE
What is the function of this protein?
dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs.
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase, dGTP triphosphohydrolase, dGTPase.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 1 subfamily.
Protein: LACB2_XENLA
Sequence: MSLSVLPRLEQLSSRVVRVLGCNPGPMTLQGTNTYLVGTGSRRILIDTGEPAVPEYISCLKQALIEFNTSIQEIIVTHWHVDHVGGIADISRDIMKGCNFSINKLPRNPHQEEVIADHKYNYLKDGDIITTEGATLRVLYTPGHTDDHMALELLEENAIFSGDCILGEGTAVFEDLYDYMKSLEKLLEMKADKIYPGHGPVVLGARAKIQEYISHRHAREQQILQALQENRGKSFTSMDLVKIVYKDTPEYLHKAAEFNLTHHLQKLKKEGKISEEQSPTVRWRSNL
What is the function of this protein?
Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA.  The cleavage product contains a free 3' -OH group.  Has no activity with double-stranded RNA or DNA.  Required for normal mitochondrial function and cell viability.
What are the official names of this protein?
Endoribonuclease LACTB2, Beta-lactamase-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: MURD_PSEF5
Sequence: MSLIASDHFRIVVGLGKSGMSLVRFLASRGVAFAVADTRENPPELATLRRDYPQVEVRCGELDVDFLCRADELYVSPGLALATPALQAAAARGVKLSGDIELFARNAKAPIVAISGSNAKSTVTTLVGEMAAAAGKRVAVGGNLGTPALDLLSDDVELYVMELSSFQLETTDQLGAEVATVLNISEDHMDRYSGLPAYHLAKHRIFRGARQVVFNRQDALTRPLIGEGLPCWTFGLSKPDFKAFGLREEDGEKYLAFEFQNLMPVRELKIRGAHNQSNALAALALGHAVGLPFDAMLAALRTFAGLEHRCQWVRDLDGVAYYNDSKATNVGAALAAIEGLGADIEGKIVLIAGGDGKGADFKDLRGPVAANCRAVILMGRDSDQIGEAIGDAVPLIRVGSLQEAVEQCRATAQPGDVVLLSPACASFDMFKNYEDRGHQFVRIVEELA
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBA_COLLI
Sequence: MVLSANDKSNVKAVFAKIGGQAGDLGGEALERLFITYPQTKTYFPHFDLSHGSAQIKGHGKKVAEALVEAANHIDDIAGALSKLSDLHAQKLRVDPVNFKLLGHCFLVVVAVHFPSLLTPEVHASLDKFVLAVGTVLTAKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-A, Alpha-A-globin, Hemoglobin alpha-A chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: FEOC_ECOLC
Sequence: MASLIQVRDLLALRGRMEATQISQTLNTPQPMINAMLQQLESMGKAVRIQEEPDGCLSGSCKSCPEGKACLREWWALR
What is the function of this protein?
May function as a transcriptional regulator that controls feoABC expression.
What are the official names of this protein?
Probable [Fe-S]-dependent transcriptional repressor.
What is the protein family that this protein belongs to?
Belongs to the FeoC family.
Protein: RL35_XANCB
Sequence: MPKIKTNRAAAKRFRKTASGKYKCGHANRSHILTKKATKRKRNLRQTNHVRAEDAGRLDRMLPYL
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: IL1AP_RAT
Sequence: MGLPWCLMSLFFCGILQSHASERCDDWGLDTMRQIQVFEDEPARIKCPLFEHFLKYNYSTAHSSGLTLIWYWTRQDRDLEEPINFRLPENRISKEKDVLWFRPTLLNDTGNYTCMLRNTTYCSKVAFPLEVVQKDSCFNSPMRLPVHRLYIEQGIHNITCPNVDGYFPSSVKPSVTWYKGCTEIVNFHNVQPKGMNLSFFIPLVSNNGNYTCVVTYLENGRLFHLTRTMTVKVVGSPKDAVPPHIYSPNDRVVYEKEPGEELVIPCKVYFSFIMDSHNEIWWTIDGKKPDDVPVDITIIESVSYSSTEDETRTQILSIKKVTPEDLKRNYVCHARNAEGEAEQAAKVKQKVIPPRYTVELACGFGATVFLVVVLIVVYHVYWLEMVLFYRAHFGTDETILDGKEYDIYVSYARNAEEEEFVLLTLRGVLENEFGYKLCIFDRDSFPGGIVTDETLSFIQKSRRLLVVLSPNYVLQGTQALLELKAGLENMASRGNINVILVQYKAVKDLKVKELKRAKSVLTVIKWKGEKSKYPQGRFWKQLQVAMPVKKSPRWSSSDKQGLSYSSLKNV
What is the function of this protein?
Coreceptor for IL1RL2 in the IL-36 signaling system (By similarity).  Coreceptor with IL1R1 in the IL-1 signaling system.  Associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways.  Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits.  Recruits TOLLIP to the signaling complex.  Does not bind to interleukin-1 alone; binding of IL1RN to IL1R1, prevents its association with IL1R1 to form a signaling complex.  The cellular response is modulated through a non-signaling association with the membrane IL1R2 decoy receptor.  Coreceptor for IL1RL1 in the IL-33 signaling system (By similarity).  Can bidirectionally induce pre- and postsynaptic differentiation of neurons by trans-synaptically binding to PTPRD (By similarity).  May play a role in IL1B-mediated costimulation of IFNG production from T-helper 1 (Th1) cells (By similarity).
What are the official names of this protein?
Interleukin-1 receptor accessory protein, IL-1 receptor accessory protein, IL-1RAcP.
What is the protein family that this protein belongs to?
Belongs to the interleukin-1 receptor family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: TNAA_VIBCM
Sequence: MENFKHLPEPFRIRVIEPVKRTTREYREKAILNAGMNPFLLDSEDVFIDLLTDSGTGAITQEMQAAMFRGDEAYSGSRSYHALARAVKDIFGYEYTIPTHQGRGAEQIYIPVLIKKREKEKGLDRSKMVALSNYFFDTTQGHTQINCCVAKNVYTEEAFDTGVKADFKGNFDLEKLEQAILEAGPANVPYIVSTITCNSAGGQPVSIANLKAVYEIAQRYDIPVIMDSARFAENAYFIQQRERDYRNWSIEEITREAYKYADGLAMSAKKDAMVQMGGLLCFKDESFFDVYTECRTLCVVQEGFPTYGGLEGGAMERLAVGLYDGMRQDWLAYRINQVEYLVNGLEAIGVICQQAGGHAAFVDAGKLLPHIPADQFPAHALACELYKVAGIRAVEIGSLLLGRDPATGKQHPCPAELLRLTIPRATYTQTHMDFIIEAFEKVKANARNVKGLEFTYEPPVLRHFTARLKEKA
What are the official names of this protein?
Tryptophanase, L-tryptophan indole-lyase, TNase.
What is the protein family that this protein belongs to?
Belongs to the beta-eliminating lyase family.
Protein: GET1_ZYGRC
Sequence: MDSGGWIVYCCIFFILLGKVLEYTSSYQDKWFTKLTLTPEARKLNSQYHELLSERLRLQEENHSISAQDNYARWTKNNRKLGELDKKLGTIRDKLQETNTSSKKVFGRVKLIGLTIPFWILKIWQRSHVVYHFPKQDLFPKLVTGVWARGWLYLALGPLQYLRNGSLNIQDYAPHGVSLGIWIWALQATINTLEFLVKQVILEKPVSPPPQKSKSATKAETKRPEKLEITDDKVELD
What is the function of this protein?
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Together with GET2, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.
What are the official names of this protein?
Golgi to ER traffic protein 1, Guided entry of tail-anchored proteins 1.
What is the protein family that this protein belongs to?
Belongs to the WRB/GET1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: TRMFO_STAAC
Sequence: MTQTVNVIGAGLAGSEAAYQLAERGIKVNLIEMRPVKQTPAHHTDKFAELVCSNSLRGNALTNGVGVLKEEMRRLNSIIIEAADKARVPAGGALAVDRHDFSGYITETLKNHENITVINEEINAIPDGYTIIATGPLTTETLAQEIVDITGKDQLYFYDAAAPIIEKESIDMDKVYLKSRYDKGEAAYLNCPMTEDEFNRFYDAVLEAEVAPVNSFEKEKYFEGCMPFEVMAERGRKTLLFGPMKPVGLEDPKTGKRPYAVVQLRQDDAAGTLYNIVGFQTHLKWGAQKEVIKLIPGLENVDIVRYGVMHRNTFINSPDVLNEKYELISQPNIQFAGQMTGVEGYVESAASGLVAGINLAHKILGKGEVVFPRETMIGSMAYYISHAKNNKNFQPMNANFGLLPSLETRIKDKKERYEAQANRALDYLENFKKTL
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIE_VIBC1
Sequence: MTDTSVQSNTALDNDTTHFGFTTVAKDEKVTKVAEVFHSVAAKYDIMNDLMSGGVHRLWKRFTIDCSGARPGQRVLDLGGGTGDLTAKFSRIVGDQGHVILADINNSMLNVGRDKLRDNGIVGNVHYVQANAEELPFPDDYFDVITISFCLRNVTDKDKALRSMFRVLKPGGRLLVLEFSKPILDPLSKVYDAYSFHLLPKMGELVANDADSYRYLAESIRMHPDQATLEGMMKEAGFENTKYYNLTGGIVALHRGYKF
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: QUEA_CLOP1
Sequence: MKVSDFYFELPEELIAQYPLEKRDSSRLMVLDKKTGEIEHRKFHDILEYLNEGDTLVLNNTRVLPARLIGEKEETGGKIEFLLLKRIEGDKWECLAKPGRKAKVGTVFTFGEGKLKAIVREIGEEGNRIIEFKYDGIFEQVLDELGQMPLPPYIHEKLEDKERYQTVYSKEKGSAAAPTAGLHFTEELLKEIKDKGVNIAYLTLHVGLGTFRPVKVDDVNNHVMHSEYYHLDKENAELINKTKEAGKRVIAVGTTSSRTLETIGDENGRVREQSGWTDIFIYPGYKFKIVDNLITNFHLPESTLIMLVSALAGQDNIMNAYNTAVKEKYRFFSFGDSMFIK
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.