PharMolix/UniProtQA huggingface dataset:
Protein: PURL_LISMH
Sequence: MPNMEPTTKEIKEQKIYQEMGLTDSEYELVCSILGREPNYTETGLFSVMWSEHCSYKNSKPVLRKFPTEGKQVLQGPGEGAGIVDIGDGLGVAFKVESHNHPSYVEPYQGAATGVGGIIRDVFSMGARPIAMLNSLRFGELDTPHAKYLVSEVVAGIAGYGNSIGIPTVGGEIQFDPCYTKNPLVNAMCVGLIEAKDIQKGQAKGIGNPVMYVGAKTGRDGIHGATFASVEFSEEGEQQRSAVQVGDPFMEKLLLEACLDVIRDHSDILVGIQDMGAAGLVSSSSEMASKAGAGLELIMDDVPQRELNMTPYEMLLSESQERMLLCVKKGHVEEIQALFERYGLEAVVIGQVTDDKMYKIIHHGEVVANVPVDALAEDAPVYHKPSKEPARYQAFQEEKAFVPAMDDVVGVWKELLAQPTIASKRHIYEQYDYQVRTDTAVVPGSDAAIVRVRGTEKAIAMTTDCNSRYLYLDPEVGGAIAVAEAARNIVCSGGKPLAITDGLNFGNPEKPEIFWEIEKAADGISAACLELDTPVISGNVSLYNETDGTGIYPTPVIGMVGLVEDLAHITTQDFKNSGDVIFLIGETKAEYSGSELQKLQQGKISGRAPELDLATEKKYQQLLLTAIQEGLVASSHDLAEGGFGVALAEATFKAGLGADVEVPFALNQLFSESQSRFLVSVKPENEAAFAQLMELEKVYRLGVVTEDDTIRVKHKEDQVTAKTTELRSIWEGAIPCLLK
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTU_BOVIN
Sequence: MAKEAASSPLEDLDLSGEEVQRLTSAFQDPEFRRMFSEYAEELTDPENRRRYEEEITALERERGVEVRFVHPEPGHVLRTSLDGTRRCFVNVCSNALVGAPSSQPGSGSAVSGRQWSLPYSLAPGREYAWGRGTRYTVYDVVFHPDAIALARRHERFRQMLDATALEAVEKQFGVKLDRRNAKTLKIKYKGTPDAAVLRTPLPGGAPARPEGEPESPFPDFPYPYRYPAAGASAAVPRPQAPSPPEAVRQPAPTEPRYSVVQRHHVDLQDYRCSRDSAPGTVPQELVVTIELPLLRSAEQAALEVTGKLLCLDSRKPDYRLRLSLPYPVDDSRGKAQFNKARRQLVVTLPVAPTASRPEPAASPEEAADPPGTDGAACASACRGEAGPAGVCAGDAISGPSRTRAADAGITTPDAPGKERVAKSEERDFGGQEISTTGTREEPPSGAGNSPGDRGGGALSTSWGDLDAGLSVGSASVRPTLGVEARETREGTGREPAYRAMGGPGTDRGEALCPPLQCSQDEESLTLLVQVPWILLQSLQGEVNPLWYKLSFSTQDLVYYSFFLQFTPENKLSTKEPEVSISSNNAVINLAKSPECHGYWREWYYGLNNYCLEERLFVNEDNVNEFLEEVLSPPFKQTLPLTPPLIEVLQVTDSKIEIHAKLQECSNSEQLHEKEERVHEGSPLTEKENTEHATISTTDSASSVAVTVLEADRCGSATCLQQGALDVSQKLFAESQQPKSEKEREFIKDKSAVYANERKDNLKEPVITEEKELDGNHPSSLLNKTAVRDTPGFDHIKETNMQDGSVQIIKDHVTHCSFSFQNNLLYDLD
What is the function of this protein?
Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella.  Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment.
What are the official names of this protein?
Protein kintoun, Dynein assembly factor 2, axonemal.
What is the protein family that this protein belongs to?
Belongs to the PIH1 family. Kintoun subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Dynein axonemal particle. Note=Localizes in the apical cytoplasm around the gamma-tubulin-positive pericentriolar region, not in the cilia.
Protein: BAG2_ARATH
Sequence: MMKMSIGTTTSGDGEMELRPGGMVVQKRTDHSSSVPRGIRVRVKYGSVHHEISINSQSTFGELKKILSGATGVHHQDMQIIYKDKERDSKMFLDLSGVKDRSKLILIEDPISQEKRLLELRKIATKEKSSKAISDISFQVERLAGQLSAFDTVIGKGGKVEEKNLENLMEMLMNQLVKLDAISGDGDVKLKKKMQEERLHKYVEALDLLKIKNSRQPQTKPKPQYKEREMLTFYEEASRKPTASSSSPPVIITTRWETFDSSSASTATLQPVRPVHPKFKWELFN
What is the function of this protein?
Co-chaperone that regulates diverse cellular pathways, such as programmed cell death and stress responses.
What are the official names of this protein?
BAG family molecular chaperone regulator 2, Bcl-2-associated athanogene 2.
Protein: FAT4_CAEEL
Sequence: MVLREQEHEPFFIKIDGKWCQIDDAVLRSHPGGSAITTYKNMDATTVFHTFHTGSKEAYQWLTELKKECPTQEPEIPDIKDDPIKGIDDVNMGTFNISEKRSAQINKSFTDLRMRVRAEGLMDGSPLFYIRKILETIFTILFAFYLQYHTYYLPSAILMGVAWQQLGWLIHEFAHHQLFKNRYYNDLASYFVGNFLQGFSSGGWKEQHNVHHAATNVVGRDGDLDLVPFYATVAEHLNNYSQDSWVMTLFRWQHVHWTFMLPFLRLSWLLQSIIFVSQMPTHYYDYYRNTAIYEQVGLSLHWAWSLGQLYFLPDWSTRIMFFLVSHLVGGFLLSHVVTFNHYSVEKFALSSNIMSNYACLQIMTTRNMRPGRFIDWLWGGLNYQIEHHLFPTMPRHNLNTVMPLVKEFAAANGLPYMVDDYFTGFWLEIEQFRNIANVAAKLTKKIA
What is the function of this protein?
Can function as a Delta(5) fatty acid desaturase and behaves as a (8-3) desaturase.  Introduces a double bond in the fatty acid chain 5 carbons away from carboxy terminal to biosynthesize polyunsaturated fatty acids (PUFAs) endogenously (PUFAs are essential for membrane structure and many cellular and physiological processes).  Acts on a variety of substrates such as dihomo-gamma-linoleoyl-CoA ((8Z,11Z,14Z)-eicosatrienoyl-CoA, 20:3n-6) to generate arachidonoyl-CoA ((5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA, 20:4n-6).  Also acts on a number of other substrates, including fatty acids that do not contain a double bond at the 8 position like (11Z,14Z,17Z)-eicosatrienoyl-CoA (20:3n-3) to produce (5Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA (20:4n-3) (PubMed:9845325, PubMed:9917342, PubMed:11972048, PubMed:26806391).  Unlike plants, Caenorhabditis elegans desaturases seem to use fatty acyl-CoAs as substrates (By similarity).
What are the official names of this protein?
Delta(5) fatty acid desaturase fat-4, FAT-4, FAT-4 Delta(5) desaturase, Fatty acid desaturase 4.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: AC4CH_SALG2
Sequence: MQPNDITFFQRFQNDILAGRKTITIRDASESHFKAGDVLRVGRFEDDGYFCTIEVTGTSTVTLDTLNEKHAQQENMSLDELKRVIAEIYPNQTQFYVIDFKCL
What is the function of this protein?
Catalyzes the hydrolysis of N(4)-acetylcytidine (ac4C).
What are the official names of this protein?
N(4)-acetylcytidine amidohydrolase, ac4C amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the N(4)-acetylcytidine amidohydrolase family.
Protein: ATPF1_RHOPB
Sequence: MTGILAEPETWVAVAFVILMGVFAYFGVHRTVLKSLDNRRDRIKAELDEAARLKEEAAALLAEYKARRASAEREAQEIIAGAKDEAERIAAEAKAKLEDFVARRTKTAEGKIALAEAQAVADVRSAAANAAVAAASTILSQSVKGQVAEGLLQRGIEEVRSKLN
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b 1, ATP synthase F(0) sector subunit b 1, ATPase subunit I 1, F-type ATPase subunit b 1, F-ATPase subunit b 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: MRAY_NEIM0
Sequence: MFLWLAHFSNWLTGLNIFQYTTFRAVMAALTALAFSLMFGPWTIRRLTALKCGQAVRTDGPQTHLVKNGTPTMGGSLILTAITVSTLLWGNWANPYIWILLGVLLATGALGFYDDWRKVVYKDPNGVSAKFKMVWQSSVAIIAGLALFYLAANSANNILIVPFFKQIALPLGVVGFLVLSYLTIVGTSNAVNLTDGLDGLATFPVVLVAAGLAIFAYVSGHYQFSQYLQLPYVAGANEVAIFCTAMCGACLGFLWFNAYPAQVFMGDVGALALGAALGTVAVIVRQEFVLVIMGGLFVVEAVSVMLQVGWYKKTKKRIFLMAPIHHHYEQKGWKETQVVVRFWIITIVLVLIGLSTLKIR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PNP_CAMJJ
Sequence: MQYSIEINKNTEIFDIDKVAKQAAGAVLMRQGKSIVLATVAREEKQVEEDFLPLTVQYIEKAYAAGKIPGGYVKRETKPSDAETLTARIIDRSLRPLFPKGYAYPTQIVVMVLSADPKVDLQVMSLNAASVALYLSDIPMKAPVCGVRIGKIDGNFILNPNNEELQNSTLDLYVAGVKDELLMIEMRALPDQKENEIFIEAPYADVLTQTTSQNMNELSEDEILEALNLAQKAILNGSNAYEEAFSKHKKNSQIELKNEIEHPEILAFIENNFQKQIKEAINQMAKSERASELNKIAKEILNLEITKDWSEESVLNTLAKVKRKLIREQILNEGKRADGRSLNEVRPISIETNILPNAHGSCLFTRGQTQALVVATLGGENDAQMIDLLTEKNPISERFMVNYNFPGFSVGEASPIKAPGRRELGHGNLAKRALYPSVDENYPYIIRLVSEILESNGSSSMATVCGGSLALKAAGVPSLKLVAGVAMGLIFEDNKHAVLTDIMGLEDHDGDMDFKVAGSKDGVTALQMDIKLGGIDQETLKQALYQAKEGRIHILNIMEEAAKEIIVNEEVLPKLELFSVDPSKIVDIIGQAGKTIKEIIEKFGVSIDLDREKGEVKIAGSQNEQIKAAKDYIINITSSQKGTKKGSKDKDISGFELGQEFQGIVKKIAPFGAFVELKNGVDGLLHSSKSKHLNLSENQSLKVKISEIKNGKISVDLCE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIR1_TRYBB
Sequence: MLETVKLVTKRDGSVEPYDEKVVRSRIVNLMSGIDSYYVDVDDLVRVVGEGVREGMSTSMLDELLAETAAYCVTKHPDYGLLAGRLAVTALHKTTTESVLDSFRVLHEHVSQATKRHAPLISEELWDIANKHSAALQQIINYERDFDFEYFGYKTLERSYLLRVHKGRGVMEVVERPQQMFLRVALGIHGEDLERVKETYDYMSQGFFTHATPTLFNAGTPFPQMSSCFLVAMREDSIDGIYDTLKQCAIISKSAGGIGIHMHNIRAAGSYIAGTNGTSNGLVPMLRVWNNTARYVDQGGGKRKGAFAIYLEPWHADIFGFLLLKKNTGKEDQRARDLFYGLWIPDLFMERVESHGTWTLMDPNTAPFLSDCYGQEFTDLYERYEREGRGVRTIQAQELWFLILESQVETGVPFMLYKDACNFKSNQKNLGTIKCSNLCTEIVEYTSRDEVAVCNLASIALPRFVKDGAFDYVALKEVTKVVTRNLNRVIDRNHYPVCEARYSNLRHRPVGIGVQGLADAFALLSLPFAHPEAKKLNRQIFETIYIAAVEASTELAEKDGPYETFKGSPASEGKLQFDLWDEERRIRGMNEDSVHSHCGLWDWDSLKERVVKVGMRNSLLIAPMPTASTSQILGNNECIEPFTSNIYVRRVLSGEFPVVNKHLVKELIRLRLWNDDMRRKIIALNGSVSGIKEIPERIRELYKVVWEIRQKDLIDMAADRGRYIDQSQSLNLFLATPTSSQLTSMHFYSWKKGLKTGMYYLRSQPAADAIKFTLDPKAMKELPKPDKQSKEEVHGSVGRGKRKRVGEKPTANHSNAGAPNLNGPPDTDGDGGCLNCGS
What is the function of this protein?
Provides the precursors necessary for DNA synthesis.  Catalyzes the rate limiting step in the de novo synthesis of deoxyribonucleotides by directly reducing ribonucleotides to the corresponding deoxyribonucleotides.
What are the official names of this protein?
Ribonucleoside-diphosphate reductase large subunit, Ribonucleotide reductase R1 subunit.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase large chain family.
Protein: CORT_MOUSE
Sequence: MMGGRGTGGKWPSAFGLLLLWGVAASALPLESGPTGQDSVQEATEGRSGLLTFLAWWHEWASQASSSTPVGGGTPGLSKSQERPPPQQPPHLDKKPCKNFFWKTFSSCK
What are the official names of this protein?
Cortistatin.
What is the protein family that this protein belongs to?
Belongs to the somatostatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: LEU1_ECO27
Sequence: MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVMEVGFPVSSPGDFESVQTIARQVKNSRVCALARCVEKDIDVAAESLKVAEAFRIHTFIATSPMHIATKLRSTLDEVIERAIYMVKRARNYTDDVEFSCEDAGRTPIADLARVVEAAINAGATTINIPDTVGYTMPFEFAGIISGLYERVPNIDKAIISVHTHDDLGLAVGNSLAAVHAGARQVEGAMNGIGERAGNCSLEEVIMAIKVRKDILNVHTAINHQEIWRTSQLVSQICNMPIPANKAIVGSGAFAHSSGIHQDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGRAAVKHRMDEMGYKESEYNLDNLYDAFLKLADKKGQVFDYDLEALAFIGKQQEEPEHFRLDYFSVQSGSNDIATAAVKLACGEEVKAEVANGNGPVDAVYQAINRITDYNVELVKYSLTAKGHGKDALGQVDIVANYNGRRFHGVGLATDIVESSAKAMVHVLNNIWRAAEVEKELQRKAQHNENNKETV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: RS19_NATTJ
Sequence: MPRSIKKGPFVDDHLLKKVKEMNKSNKKQVIKTWSRRSTILPDMIGHTIAVHDGRKHVPVFITEDMVGHKLGEFAPTRTFRGHGDHTERSTSLK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: PINS1_PICGL
Sequence: MALVSIAPLASKSCLHKSLSSSAHELKTICRTIPTLGMSRRGKSATPSMSMSLTTTVSDDGVQRRMGDFHSNLWNDDFIQSLSTSYGEPSYREQAERLIGEVKKMFNSMSSEDGELINPHNDLIQRVWMVDSVERLGIERHFKNEIKSALDYVYSYWSEKGIGCGRESVVADLNSTALGLRTLRLHGYAVSADVLNLFKDQNGQFACSPSQTEEEIRSVLSLYRASLIAFPGEKVMEEAEIFSAKYLEEALQKISVSSLSQEIRDVLEYGWHTYLPRMEARNHIDVFGQDTQNSKSCINTEKLLELAKLEFNIFHSLQKRELEYLVRWWKDSGSPQMTFGRHRHVEYYTLASCIAFEPQHSGFRLGFAKTCHIITILDDMYDTFGTVDELELFTAAMKRWNPSAADCLPEYMKGMYMIVYDTVNEICQEAEKAQGRNTLDYARQAWDEYLDSYMQEAKWIVTGYLPTFAEYYENGKVSSGHRTAALQPILTMDIPFPPHILKEVDFPSKLNDLACAILRLRGDTRCYKADRARGEEASSISCYMKDNPGVTEEDALDHINAMISDVIRGLNWELLNPNSSVPISSKKHVFDISRAFHYEYKYRDGYSVANIETKSLVKRTVIDPVTL
What is the function of this protein?
Terpene synthase (TPS) involved in the biosynthesis of monoterpene natural products included in conifer oleoresin secretions and volatile emissions; these compounds contribute to biotic and abiotic stress defense against herbivores and pathogens (PubMed:21385377).  Catalyzes the conversion of (2E)-geranyl diphosphate (GPP) to (1S,5S)-beta-pinene (PubMed:21385377).
What are the official names of this protein?
(-)-alpha-pinene synthase 1, chloroplastic, (-)-beta-pinene synthase 1, Terpene synthase TPS-Pin-1, PgTPS-Pin-1.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsd subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: IPYR_ORYSJ
Sequence: MAGEADGKAPLGSRYPPAALNERILSSMSQKHVAAHPWHDLEIGPGAPAVFNCVVEIPRGSKVKYELDKATGLIKVDRVLYSSVVYPHNYGFIPRTLCEDGDPMDVLVLMQEQVVPGCFLRARAIGLMPMIDQGEKDDKIIAVCADDPEYRHFRDIKEIPPHRLQEIRRFFEDYKKNENKEVAVNEFLPAEDAINAIKYSMDLYGAYIIESLRK
What are the official names of this protein?
Soluble inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_CHRVO
Sequence: MLVLGIESSCDETGVALYDTERGLLAHQLHTQMAMHAEYGGVVPELASRDHIRRAIPLTEACLSEAGKKLADLDAIAYTQGPGLGGALMVGASMANALAFGLNIPVIPVHHLEGHLLSPLLADPKPEFPFLALLVSGGHTQLMAVRGVGDYEILGETVDDAAGEAFDKTAKLLGLPYPGGPLLSRLAESGSPDRFTLPRPMLHSGNLDMSFSGLKTAVLTLVRQQESAQGELDEQTRMDICRAFQEAIVEVLVKKSLAAMRQAGMKRLVVAGGVGANKQLRAALNDAAARKRFDVFYPPLALCTDNGAMIAFAGAMRLKFAEPAGGFTIKPRWDLSSLPAV
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y366_ACTP2
Sequence: MSLQFNPISLFLVVLIFLGVVGNNNSITIAATVLLLVQQTFLSKYLPFLDKHGLSIGIIILTIGVLSPIVSGKISLPSFSEFLNWKMLLAVVAGIAVAWLGGRGVSLMGGQPLLVTGLLVGTIIGVALLGGVPVGPLIAAGILSLLIGKG
What are the official names of this protein?
UPF0756 membrane protein APL_0366.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SSP51_PHAJA
Sequence: LLGMIPVAISAINLMKL
What are the official names of this protein?
Skin secreted peptide P5-1, PjP5-1.
What are the subcellular locations of this protein?
Secreted.
Protein: ZN423_DANRE
Sequence: MSRRKQAKPRSVKAVEEAESTECASGWDSSVQTDAAVSERDSDRKESRAVGEDGEQSVTSHDERVGEEDLDDDSIFTCDNCQQDFECLADLTEHRTNHCPADGDDDPGLSWVASSPSSKDVASPSQMLGDGCCDMGMGTGEEEGGSGLPYPCQFCDKSFSRLSYLKRHEQIHSDKLPFKCTFCSRLFKHKRSRDRHVKLHTGDKKYSCQECEAAFSRSDHLKIHLKTHSSSKPFKCSICKRGFSSTSSLQSHMQAHRKNKEHLAKKDQGKRDGSSSDVTEQDQDLYMCDYCEETFSQTDELEKHVLTQHPQLSDRAELQCIHCPEIFSDEGTLLTHIDRTHANKKHKCPMCAEQFPSVEDVYCHLDSHRQPDSSNHSASPDPVLGSVASMSSATPDSSASLERGSTPDSTLKPGQSRRKLAPSSDHDDGTWSGKVTYSCPYCSKRDFNSLAVLEIHLKTIHADKPQQSHTCQLCLETLPTLYNLNEHVRKAHRSSGNSASNFPLLQFSNVSAFHCNYCPDMFADINSLQEHIRVSHCLSGGVVAGSTTLEGNHAFFCNQCSMGFLTESSLTEHIQQTHCSSVGGVTKMESPVLQPSQSFMEVYSCPYCTNSPIFGSLLKLTKHIKENHKNIPLANNKRKVKVADLSPASSDVEISSPKRHRVTGDSTPAVANGDYPCNQCDLRFSSFEGFQAHLKSHLELLLRRQSCPQCNKEDFDSQEALLQHLTIHYTTTSTQYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACAWDFRKESDLQLHVKHSHLGHPASTGAPGKARKCIFCGETFGTEVELQCHITTHSKKYNCRLCGKAFHAIVLLERHLREKHCIFDGGNGNGNGGSQNGTPNGVTQSSKRSTAGSTAAAEQADLQNMLLKGGSQETANSHEASGGEEELDASEPMYACDICGAAYTMESLLQNHRLRDHNIRPGEDDAGSRKKKADFIKGNHKCNVCSRTFFSENGLREHAQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKLSSSGGSGGGGGSASSSPNGQLQAHKLYKCALCLKDFKNKQELVKIDVNGLPYGLCAGCMSRGTNGQSPTVVVTPQEAGDKGTTGLRCSECAVKFETLEDLESHIQVDHTEMSPETSGAKKVTDASPVPKKKTYQCIKCQMTFETEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTELQNHTLSQHAQ
What is the function of this protein?
Transcription factor that can both act as an activator or a repressor depending on the context.  Plays a central role in BMP signaling and olfactory neurogenesis.  Associates with SMADs in response to bmp2 leading to activate transcription of BMP target genes.  Acts as a transcriptional repressor involved in terminal olfactory receptor neurons differentiation.  Involved in olfactory neurogenesis by participating in a developmental switch that regulates the transition from differentiation to maturation in olfactory receptor neurons (By similarity).
What are the official names of this protein?
Zinc finger protein 423.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: S39A1_TAKRU
Sequence: MEYLLQVKIAALVGLLFLTLIFGFIPARVKWFRDTDGTETHRTVLSLISCFAGGVFLSACFLDIIPDYLSDINTELHARQLETSFPLPEFIMAAGFFTVLILERIVLNCKEMRATHEERTTLIPERKSGHGHGHGDGPDPESSGHHVHVDFQAHSPFRSFMLFLSLSLHSIFEGLAIGLQTTDPKVVEICIAILVHKSIIVFSLAVKLVQSAIPPLWVAAYIGVFALMSPVGIAIGISVMEAQLAAGPLIQAILEGFAAGTFVYITFLEILPHELNSPGKQLLKVLFLLLGFSIMAALSFLG
What is the function of this protein?
Transporter for the divalent cation Zn(2+).  Mediates the influx of Zn(2+) into cells from extracellular space.
What are the official names of this protein?
Zinc transporter ZIP1, Solute carrier family 39 member 1, Zrt- and Irt-like protein 1, ZIP-1.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SAPD_ECOLI
Sequence: MPLLDIRNLTIEFKTGDEWVKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGVNKDNWRVTADRMRFDDIDLLRLSARERRKLVGHNVSMIFQEPQSCLDPSERVGRQLMQNIPAWTYKGRWWQRFGWRKRRAIELLHRVGIKDHKDAMRSFPYELTEGECQKVMIAIALANQPRLLIADEPTNSMEPTTQAQIFRLLTRLNQNSNTTILLISHDLQMLSQWADKINVLYCGQTVETAPSKELVTMPHHPYTQALIRAIPDFGSAMPHKSRLNTLPGAIPLLEQLPIGCRLGPRCPYAQRECIVTPRLTGAKNHLYACHFPLNMEKE
What is the function of this protein?
Part of a putrescine export transport system, does not play a role in resistance to antimicrobial peptides (PubMed:27803167).  Stimulates K(+)-uptake proteins TrkG and TrkH to import K(+), may act via ATP-binding rather than ATP hydrolysis (PubMed:11700350).
What are the official names of this protein?
Putrescine export system ATP-binding protein SapD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: INT6_DROME
Sequence: MTIILFLVDTSSSMCQKAYVNGVQKTYLDIAKGAVETFLKYRQRTQDCLGDRYMLLTFEEPPANVKAGWKENHATFMNELKNLQSHGLTSMGESLRNAFDLLNLNRMQSGIDTYGQGRCPFYLEPSVIIVITDGGRYSYRNGVHQEIILPLSNQIPGTKFTKEPFRWDQRLFSLVLRMPGNKIDERVDGKVPHDDSPIERMCEVTGGRSYRVRSHYVLNQCIESLVQKVQPGVVLQFEPMLPKEATSATAGEAAGASTISGMGISSTSGAGPAPDIVFQPVKKMIYVQKHITQKTFPIGYWPLPEPYWPDSKAITLPPRDAHPKLKVLTPAVDEPQLVRSFPVDKYEIEGCPLTLQILNKREMNKCWQVIVTNGMHGFELPFGYLKAAPNFSQVHLYVLAYNYPALLPILHDLIHKYNMSPPSDLMYKFNAYVRSIPPYYCPFLRKALVNINVPYQLLQFLLPENVDNYLSPTIANQLKHIKNTAKQDQENLCMKVYKQLKQPKPPYRQVETGKLFTGAPLRRDLVRHPLLRDIFSKLHGEIDPVENYTIVVPQPTHQSSAKSHRNPFDIPRRDLVEEIAKMRETLLRPVSLVAKDSGHCLPIAEMGNYQEYLKNKDNPLREIEPTNVRQHMFGNPYKKDKHMVMVDEADLSDVAPMKSPNGNGPGGAPPGSPSGSGSPTGPGPSSPGSSPGGGSGPGMPGMPGMGGGMSGLMLGAGGSGGSSKKLDGTSRGRKRKAGPLPRSFEFRRSSTDSRSSSSGSESSTTGSAPGSPIPGATSSISGCDSAMGADGGPSSSCFDEDSNSNSSFVSSTSEASASDSGMSNSHLDPLRISFVFIEEETSDQDTPLNGYVHNFINGISDDAETGETEAVPGGASLPGASSANEPSSIGASPAVSATPATSVIPASNGSEVCSAVAAGSSSSISSSASSPGVLYVPLNGLTTHAAYSSNLGGPSSPLDNLSSLGGAAGGGGSGLLGVSKPGSLPLANGYGHGHSSAISPPSPLSLVPLSPLGTSTPAASSSGLSSSSAYFSHNDINDASEISRILQTCHNGTSSGSSVGAGASNSNLNGNGSTESGGGVSSDDHASLGGNSFDALKRTAGTAGSTAAGNPHYYWASGLNHHNNNNSSAAGAASGSTLSNNHNHRGHNNSSPNKLEVKINSSCGSSPTHNNGGMGSPGQSLPLIFTEEQREAARLHNVELRLQIFRDIRRPGRDYSQLLEHLNLVKGDQDMQSDFVDMCIVESLRFRRHRMASSIQEWWDRKQQLTAVGTNEATPSAEQAVAKS
What is the function of this protein?
Component of the Integrator complex, a complex involved in the transcription of small nuclear RNAs (snRNA) and their 3'-box-dependent processing (PubMed:21078872, PubMed:23097424).  Involved in the 3'-end processing of the U7 snRNA, and also the spliceosomal snRNAs U1, U2, U4 and U5 (PubMed:21078872, PubMed:23097424).  May mediate recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (By similarity).
What are the official names of this protein?
Integrator complex subunit 6.
What is the protein family that this protein belongs to?
Belongs to the Integrator subunit 6 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PYRF_METNO
Sequence: MPDTPSPRDRLIVALDMATTDEAERLIDRLGDAASFYKIGYRLGYAGGLALAERLVKGGAKVFLDLKLHDIGNTVEEGVQSLARLGAHLLTVHAYPQTMRAAVRGRDSVPGSALRLLAVTVLTSYDDADAREAGYALSVSELVAIRALAAREIGIDGIVCAATEAAQVREIVGPDGLIVTPGIRPAGSDTGDQKRVVTPAAAIRAGVDYIVVGRPITAAADPRAVAQSIVAEIAAA
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: PYRH_STAA8
Sequence: MAQISKYKRVVLKLSGEALAGEKGFGINPVIIKSVAEQVAEVAKMDCEIAVIVGGGNIWRGKTGSDLGMDRGTADYMGMLATVMNALALQDSLEQLDCDTRVLTSIEMKQVAEPYIRRRAIRHLEKKRVVIFAAGIGNPYFSTDTTAALRAAEVEADVILMGKNNVDGVYSADPKVNKDAVKYEHLTHIQMLQEGLQVMDSTASSFCMDNNIPLTVFSIMEEGNIKRAVMGEKIGTLITK
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQAM_BACSU
Sequence: MAINKAVSIDTAFQTIMQELRERSARFLGTKQAVSEEKAEFDCPYCKDRGIVVYRVHKDTSWHLDEQLDLMVPDDMVSEDDFLLGKVCTPDKASEWKDTYSKQCECVRRKKIARLMAASGITEEFEKLLFGNFITDGKPDMIKDAYECAVEYYKDFQKIKGERQNSIALLGQPGSGKTHLLTAIMNNLIKKKSVHCMYFPYVEGMGDLKANFDNLEAKLDAMRKVEVLFIDDLFKPINGQPRATDWQVEQIQSVLNYRYLNHKPLLISSELTIDEILDIDEALGSRIHQMCRDYIVIIRGDRMQLNHRLGDWE
What are the official names of this protein?
Uncharacterized protein YqaM.
What is the protein family that this protein belongs to?
To B.subtilis YqxC and T.hyodysenteriae hemolysin TlyA.