PharMolix/UniProtQA huggingface dataset:
Protein: ALG11_ASHGO
Sequence: MESCWLTMESYQAALVVCIVSGLILAVAGYGNVRRLACEFLLKPPKRFRDDICEALLRGPENDQKPVLVDFGWRHGAVRRQMLLASAKASAYSNERHGSKIHISPDDIARGRSFADALDVHRRSGRILFGFFHPFCNAGGGGEKVLWKAVETTLKQSLNNIVVVYTGDCDTTGARILSNVEHRFGSQLDSERIVFIFLRHRKWVESRTWPRMTLLGQALGSIVLSIEAALCCPPDVWCDTMGYPFGYPFVSWLCRIPIITYTHYPVVSIDMLDKLRMMPEFRNSPTLWAKFLYWRIFMRCYTFAGSFVDLAVTNSTWTYNHINAIWSRTGNVSIIYPPCSTENLVIENAHDMWDRKHQAVVIAQFRPEKRHALILRSFSNFVKKTGSNMKLLMLGSTRGQEDRDYVKKLEQLAYSELAIPKESLEFITDCKYEKMKKYLQESSFGINAMWNEHFGIAVVEYAASGLITLAHASAGPLLDIIVPWDIEGDKQLERGSDKNRTGFFFKDRSDPDFCKITAEFPTLEELFVRADQLTDEERLAISQRAKRCVLHKFSDLKFSEDWAQVVDRTIQLLHTLRNDKVE
What is the function of this protein?
Required for N-linked oligosaccharide assembly.  Has a role in the last step of the synthesis of the Man(5)GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum (By similarity).
What are the official names of this protein?
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase, Alpha-1,2-mannosyltransferase ALG11, Asparagine-linked glycosylation protein 11, Glycolipid 2-alpha-mannosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: LLDD_HAEIG
Sequence: MIISSASDYREAARRRVPPFMFHYADGGSYAEQTLARNVSDLENIALRQRVLKDMSELDTSIELFGEKLSMPTILAPVGACGMYARRGEVQAAQAADNKGVPFTLSTVSICPIEEVAPAIKRPMWFQLYVLKDRGFMKNALERAKAAGCSTLVFTVDMPTPGARYRDMHSGMSGPYKEIRRVLQGFTHPFWAYDVGIKGKPHTLGNVSTYMGRQIGLDDYIGWLTENFDPSISWKDLEWIREFWEGPMVIKGILDPEDAKDAVRFGADGIVVSNHGGRQLDGVLSSARALPPIADAVKGDIKIIADSGIRNGLDIVRMLALGADATMLGRAFVYALGAAGRQGVENMLDIFKKEMHVAMTLTSNRTIADIKPEALVDLSKL
What is the function of this protein?
Catalyzes the conversion of L-lactate to pyruvate.  Is coupled to the respiratory chain.
What are the official names of this protein?
L-lactate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MTNB_PARBA
Sequence: MSDIKDGNNDHLVQSDDPEHPANLIPALCRNFYSHGWVTGTGGGASIKRDNHIFIAPSGVQKELIQPHNIFVLSFPTPKYPPSARQYIRKPLKLNPSACTPLFLAAFERGAGCCIHTHSQWAVLVTLLVEREKGPEGCFEISNIEQIKGIPRGKGKGMMGFFDTLKIPIIENTAFEEDLTQSLEEAMEMYPDTYAVLVRRHGIYVWGDDVAKAKTQCESLDYLFQLAVEMHRLGLPWVKS
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
What are the official names of this protein?
Methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_BAUCH
Sequence: MARYFRRRKFCRFTAEDVIEIDYKDIATLKNYITESGKIVPSRITGTRAKYQRQLARAIKRARYLSLLPYTDLHQ
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: MIAB_ZYMMO
Sequence: MNRPSLKHFYIKSFGCQMNSYDGERMSELLESQGMKAAEEAATADLVVLNTCHIREKAAEKVYSEIGRLRRPDGSSPMIALAGCVAQAEGAEVLARTKMVDIVVGPQAYHHLPELIEKAASGKVVDIDMPLESKFDALPERRQVGASAFLTVQEGCDKFCTYCVVPYTRGAEVSRPWSRIVKEAHALVDKGAREITLLGQNVNAWTGEDEAGRSQGLDGLIRALAKIDGLERIRYTTSHPNDMTEGLIEAHGEIDKLMPFLHLPVQSGSNRILKAMNRAHTAESYLTLMNRLKEVRPDIALSGDFIVGFPGESEEDFQATLDLISEVGYSLAFSFAYSPRPGTPAADMDNQIDPEISRERLQRLQALLNQQQFDFNQQTIGRKATVLIERKGKKADQMIGKSPWLQSVIIEAPVAIGDLVEVTLTDAGPNSVKGQFLDQKQFATA
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCIN_RAT
Sequence: MHACEGSAAGRRAFDSICPNRMLDLSRRSLGKPGKPERKFVPPWKSFPGCGGGSPVSVYEDPLDAEPAPLPALTTIDLQDLADCTSLLGTEAPPSGDSPASQNPSLQTEADFNLQNFRDAVDDLIADSSSLTSPPLTDGDFPFSPCDVPSFGSCLSPSLDPPALGSPHLPPPPTEQYWKEVADQNQRALGTALIENNQLHVTLTQKQEEIASLRERNVQLKELACRTRHLASVLDKLMITQSPAEPFQLKATTKRSLEELFSATGQAGQGCAEVDAILRDISQRCEEALQNRDPKRPRLQQEPDSKDCSTRNLHGVFRGLRTDCGASSVNLSHSELEEGGSFSTPIRSHSTIRTLAFPQGKAFTIRTVTGGYKFRWVPS
What is the function of this protein?
Transcription regulator specifically required for multiciliate cell differentiation.  Acts in a multiprotein complex containing E2F4 and E2F5 that binds and activates genes required for centriole biogenesis.  Required for the deuterosome-mediated acentriolar pathway.  Plays a role in mitotic cell cycle progression by promoting cell cycle exit.  Modulates GMNN activity by reducing its affinity for CDT1.
What are the official names of this protein?
Multicilin, Multiciliate differentiation and DNA synthesis-associated cell cycle protein, McIdas protein, Protein Idas.
What is the protein family that this protein belongs to?
Belongs to the geminin family.
What are the subcellular locations of this protein?
Nucleus. Note=Excluded from the nucleolus.
Protein: PSBJ_WHEAT
Sequence: MSDTTGRIPLCLIGTVAGIAVIGLVGVFFYGSYSGLGSSL
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein J, PSII-J.
What is the protein family that this protein belongs to?
Belongs to the PsbJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: Y2003_STRP8
Sequence: MTFTIMTDSTADLNQTWAEDHDIVLIGLTILCDGEVYETVGPNRISSDYLLKKMKAGSHPQTSQINVGEFEKVFREHARNNKALLYLAFSSVLSGTYQSALMARDLVREDYPDAVIEIVDTLAAAGGEGYLTILAAEARDSGKNLLETKDIVEAVIPRLRTYFLVDDLFHLMRGGRLSKGSAFLGSLASIKPLLWIDEEGKLVPIAKIRGRQKAIKEMVAQVEKDIADSTVIVSYTSDQGSAEKLREELLAHENISDVLMMPLGPVISAHVGPNTLAVFVIGQNSR
What is the function of this protein?
May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.
What are the official names of this protein?
DegV domain-containing protein spyM18_2003.
Protein: SPS1_XENLA
Sequence: MSVRESFNPESYELDKSFRLTRFAELKGTGCKVPQDVLQKLLESLQENHFQEDEQFLGAVMPRLGIGMDTCVIPLRHGGLSLVQTTDYIYPIVDDPYMMGRIACANVLSDLYAMGVTECDNMLMLLGVSNKLTDRERDKVMPLIIQGFKDAAEEAGTSVTGGQTVLNPWVVLGGVATTVCQPNEFIMPDNAVPGDVLVLTKPLGTQVAVAVHQWLDIPEKWNKIKLVVTQEDVELAYQEAMMNMARLNRTAAGLMHTFNAHAATDITGFGILGHAQNLAKQQRNEVSFVIHNLPVLAKMAAVSKACGNMFGLMHGSCPETSGGLLICLPREQAARFCAEIKSPKYGEGHQAWIIGIVEKGNRTARIIDKPRIIEVAPQIATQNVNPTPGATS
What is the function of this protein?
Synthesizes selenophosphate from selenide and ATP.
What are the official names of this protein?
Selenide, water dikinase 1, Selenium donor protein 1, Selenophosphate synthase 1.
What is the protein family that this protein belongs to?
Belongs to the selenophosphate synthase 1 family. Class II subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Nucleus membrane; Peripheral membrane protein.
Protein: AMAB2_GEOSE
Sequence: MIQGERLWQRLMELGEVGKQPSGGVTRLSFTAEERRAKDLVASYMREAGLFVYEDAAGNLIGRKEGTNPDATVVLVGSHLDSVYNGGCFDGPLGVLAGVEVVQTMNEHGVVTHHPIEVVAFTDEEGARFRFGMIGSRAMAGTLPPEALECRDAEGISLAEAMKQAGLDPDRLPQAARKPGTVKAYVELHIEQGRVLEETGLPVGIVTGIAGLIWVKFTIEGKAEHAGATPMSLRRDPMAAAAQIIIVIEEEARRTGTTVGTVGQLHVYPGGINVIPERVEFVLDLRDLKAEVRDQVWKAIAVRAETIAKERNVRVTTERLQEMPPVLCSDEVKRAAEAACQKLGYPSFWLPSGAAHDSVQLAPICPIGMIFVRSQDGVSHSPAEWSTKEDCAAGAEVLYHTVWQLAQGE
What are the official names of this protein?
N-carbamoyl-L-amino acid hydrolase, L-carbamoylase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20 family.
Protein: AGL9_ARADE
Sequence: MGRGRVELKMIENKINRQVTFAKRRKRLLKKAYELSVLCDAEVALIIFSNRGKLYEFCSSTSMLKTLEKYQKCNFGSPESTIISRETQSSQQEYLKLKNRVEALQRSQRNLLGEDLGPLGSKELEQLERQLDSSLRQIRSTRTQFMLDQLADLQRREQMLCEANKTLKRRFEESSQANQQQVWDPSNTHAVGYGRQPAQHHGEAFYHPLECEPTLQIGYHSDITMATATASTVNNYMPPGWLGQISGSYE
What is the function of this protein?
Probable transcription factor active in inflorescence development and floral organogenesis.
What are the official names of this protein?
Agamous-like MADS-box protein AGL9 homolog, OM1.
What are the subcellular locations of this protein?
Nucleus.
Protein: MLTC_SERP5
Sequence: MKKILALLVIAPLLISCSGKKNTEVNEALVKDTNGFEILMGQFAHNIENIWGLNEVLIAGPKDYVKYTDQYQTRSHINFDSGAITIETIATTDPAAHLRQAIISTLLMGDDPGSIDLYSDVNDIQISKEPFLYGQVLDNKGAPIRWEWRAAHFADYLVQTKLQKRTSGLHVIYSVTIQLVPNHLDKRAHKYLPMVRKASEKYGVEESLILAIMQTESSFNPYAVSGSDALGLMQVVQHTAGKDVFQMRGKWGKPSRSYLFDPENNIDTGTAYLAILQNNYLGGIQNPTSRRYAVITAYNGGAGSVLRVFSSDRTRAVGIINGMQPGDVYQTLTTKHPASESRHYLVKVNNAQKSYRRR
What is the function of this protein?
Murein-degrading enzyme.  May play a role in recycling of muropeptides during cell elongation and/or cell division.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase C, Murein lyase C.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: CH10_STRPN
Sequence: MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQGVRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZNUC_RUEST
Sequence: MRLVSLRNATIRHSGTPALENVDFHIDRGEIVTILGPNGSGKSTLLRSIIGALPLSSGTVERAQDLRIGYVPQKLHIDPTLPLTVERFLSLPVRISKTETENALAEAGVPGLRKRQMTGLSGGQMQRVLLARALLSKPDLLILDEATQGLDQPGSAAFYQKIASVRSQIGCAVLMVSHELHVVMAASDRVICLNGHVCCEGAPAQVASAPEYQALFGSGTHGALALYRHEHDHSHDCDHDHAKDEHEHA
What is the function of this protein?
Part of the ABC transporter complex ZnuABC involved in zinc import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Zinc import ATP-binding protein ZnuC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ARNB_YERE8
Sequence: MQNFLPFSRPAIGSDEINAVVNVLGSGWITTGPQNQQLETDFCAAFGCKHAVAVCSATAGMHITLMALGIGPGDEVITPSQTWVSTINMIVLLGAEPVMVDIDRDTLMVNAADIEAAITSKTKAIIPVHYAGAPCDLDALRQIAQQYKIPLIEDAAHAVGTRYGDQWVGEKGTTIFSFHAIKNITCAEGGLIATDDDELAAKVRRLKFHGLGVDAFDRQIQGRSPQAEVVEPGYKYNLSDIHAAIAVVQLQRLPEINARRQALAARYHQALVDSPLQPLFVPDYAHQHAWHLFMVRVDKERCGIDRDSLMARLKEVGIGSGLHFRAAHTQKYYRERYPSLHLPNTEWNSARLCTLPLFPDMLDSDVDRVVDALATIIGPHRV
What is the function of this protein?
Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase, UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase, UDP-Ara4O aminotransferase, UDP-4-amino-4-deoxy-L-arabinose aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.
Protein: GLTC_BACSU
Sequence: MELRQLRYFMEVAEREHVSEAADHLHVAQSAISRQIANLEEELNVTLFEREGRNIKLTPIGKEFLIHVKTAMKAIDYAKEQIDEYLDPHRGTVKIGFPTSLASQLLPTVISAFKEEYPHVEFLLRQGSYKFLIEAVRNRDIDLALLGPVPTNFSDITGKILFTEKIYALVPLNHPLAKQKTVHLIDLRNDQFVLFPEGFVLREMAIDTCKQAGFAPLVSTEGEDLDAIKGLVSAGMGVTLLPESTFAETTPRFTVKIPIEFPQVKRTVGIIKPKNRELAPSANDFYEFVIQFFSKLEQYQ
What is the function of this protein?
Positive regulator of glutamate biosynthesis (gltAB genes).  Negatively regulates its own expression.
What are the official names of this protein?
Transcriptional dual regulator GltC, HTH-type transcriptional regulator GltC.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: YCIB_BURVG
Sequence: MKFLFDLFPIILFFAAFKVWGIFTATAVAIVATLAQVAWVAFRHRKVDTMLWVSLGVIVVFGGATLVLHDEKFIQWKPTVLYWLFAIGLLAARYAFGNNLIEKMMGKQLTLPHPVWDKLNVAWALFFAVLGLANLYVVHNFTESQWVNFKLFGTTGAMVVFIILQSLWLTKYLKDE
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YORF3_TTVVG
Sequence: MFGDPKPYNPSSNDWKEEYEACKYWDRPPRGNLRDTPYYPWAPKENQYRVNFKLGFQ
What are the official names of this protein?
Uncharacterized ORF3 protein.
Protein: TRMY_PYRFU
Sequence: MRIFIIKSSTAHTAFDYSIKDIPGTSGRLDLICRSLNAAFQLSHSFRKNVRVYTVLYGPPDPPKTIRFEGAKIKPKTLNPDEVSTAKLIGKILNAGKDIKEPTKEREVLPGIYISRMTFEDVVRKNIKYNLYLLEENGVDIEKVKFPQDNVGFILGDQNGFTEEELNFLEGLVPKITIGPKPYLTSHVIAFVNIYLDRIGIP
What is the function of this protein?
Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs.
What are the official names of this protein?
tRNA (pseudouridine(54)-N(1))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. TrmY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_STRA5
Sequence: MIANQTIVDIVTQVVTPAIQAPFELVDVEYEKMGGDYVLSILIDKPGGITVEDTAQLTDVVSPLLDTIQPDPFPEQYMLEVSSPGLERPLKTAEALSNAVGSYINVSLYKSIDKVKIFEGDLLSFDGETLTIDYMDKTRHKTVDIPYQTVAKARLAVKL
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_CUPNH
Sequence: MQLVIVAVGHKMPGWIETGFSEYAKRMPPELRIELREVKPETRSSSNNAATVMQREAARIEAVLGSLSKQCRIVALDERGRDFTTVQLAAQLTDWQREGGDVAFLIGGADGLDPALKARASTLIRLSSLTLPHGMVRVLLAEQLYRAWSVTQNHPYHRA
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1228_ARCFU
Sequence: MLEKIYSVLGTGSCLVKDGEIIESYLLSDEEVKLIEKIAKVIPFLPEKFKVGFFEHEGGRIIAIKHGEVFICFPARSDNVMSELRKVEVEVYDKILSP
What are the official names of this protein?
Uncharacterized protein AF_1228.
Protein: FMT_BACTN
Sequence: MKKEDLRIVYMGTPDFAVEALRQLVEGGYNVVGVITMPDKPAGRGHKIQYSPVKQYALEQNLPLLQPEKLKDEAFVQALREWKADLQIVVAFRMLPEVVWNMPRLGTFNLHASLLPQYRGAAPINWAVINGDTETGITTFFLQHEIDTGKVIQQVRVPIADTDNVEVVHDKLMILGGKLVLETVDAILNDTVKPIAQEDMAVVGELRPAPKIFKETCRIDWNSPVKKVYDFIRGLSPYPAAWSELVSPEGEAVVMKIFESEKIYEAHQLPVGTVVTDGKKYIKVAVPDGFVSVLSLQLPGKKRLKTDELLRGFRLSDGYKMN
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: PTXBC_STAES
Sequence: MSKEERLAKDITHALGGSQNISNIIHCMTRVRIKVHNDAKVNYDELKSINGVLGVVEDERIQVVVGPGIVNKVAKLMADQSGATLAEETTENQSYKSQAEKRAYEHKKQFQSQRKQSKWNKVLKSIANIFIPLIPAFIGAGLIGGIAAILSNLLTAGSISGQWIQQIVTVLNVIKDGMLFYLAIFTGINSAKVFGATPGLGGVIGGTTLLTGITDENPIKNIFTGEHLAAGQGGIIGVIFAVWLLSMVEKRLHKIIPNSIDIIVTPTITLLLIGLLTIFIIMPLAGFVSDGLVYVINWIIGVGGIFSGFIIGAFFLPLVMLGLHHIFTPIHIELINQTGSTYLLPIAAMAGAGQVGAAIALWVRCGKNKELRNTLKGALPVGFLGIGEPLIYGVTLPLGRPFFTACIGGGVGGAVIGGIGHIGATAVGPSGISLLPLIANNMYLGYIVGLLAAYAGGFIFTYFFGTTKEMRNPE
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  This system is involved in the uptake and phosphorylation of MurNAc-GlcNAc, the principle peptidoglycan turnover product of S. aureus, yielding cytoplasmic MurNAc 6P-GlcNAc.
What are the official names of this protein?
PTS system MurNAc-GlcNAc-specific EIIBC component.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RF1_RUTMC
Sequence: MHASIFAKLEQLSMRLEEVDVMLSNPKVASDVKKFTKLSIERAQLTPVNQQFQAYLSHHRNLEDAKLMLLEDDMDIKAMAKEEMLDVKKKLDHLYLELKKSLLPKDPNDSRNIIIEIRAGTGGNEASIFSSNLFKMYSRYTEKKKWQIEVISSSLGEHGGFKEIIARISGVGVYSKLKFESGAHRVQRVPETESQGRVHTSACTIAIMPEVENIEEVNINMSDVRVDTFRASGAGGQHVNKTNSAVRITHIPTGTVAECQDGRSQHKNKAQALLVLASRIFDLQQQEQHKEQASTRKELIGSGDRSQRIRTYNYPQGRITDHRINLTLYKLSEIMEGNLNAIIEPLIVEQQTSQLTELNDVLS
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURI_LEPBJ
Sequence: MKGPLKIGLMDSGMGGLSVLKGILKYDAELEVVYYGDLKNSPYGEKETSEILELVRDVCKRLQEENVSAILLACNTATSAAAQTLRKEFSIPIFGMEPAIKPAILQNPGKKIALLATPVTQREKKLQRLKAELGAEELILPVSCPGLAGLVDKGEFDEAEKYLRPILKKLREENVENLVLGCTHYIFLKHIILKNFPNVRIYDGNSGTIKHLLNSLQVRQRVSNRSSVSGSVYKLILNSDEELHFRLATELLQFENKF
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: MBP_MOUSE
Sequence: MGNHSGKRELSAEKASKDGEIHRGEAGKKRSVGKLSQTASEDSDVFGEADAIQNNGTSAEDTAVTDSKHTADPKNNWQGAHPADPGNRPHLIRLFSRDAPGREDNTFKDRPSESDELQTIQEDPTAASGGLDVMASQKRPSQRSKYLATASTMDHARHGFLPRHRDTGILDSIGRFFSGDRGAPKRGSGKDSHTRTTHYGSLPQKSQHGRTQDENPVVHFFKNIVTPRTPPPSQGKGGRDSRSGSPMARR
What is the function of this protein?
The classic group of MBP isoforms (isoform 4-isoform 13) are with PLP the most abundant protein components of the myelin membrane in the CNS.  They have a role in both its formation and stabilization.  The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells.  Differential splicing events combined to optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function.
What are the official names of this protein?
Myelin basic protein, MBP, Myelin A1 protein.
What is the protein family that this protein belongs to?
Belongs to the myelin basic protein family.
What are the subcellular locations of this protein?
[Isoform 13]: Myelin membrane; Peripheral membrane protein; Cytoplasmic side. SUBCELLULAR LOCATION: [Isoform 12]: Myelin membrane; Peripheral membrane protein; Cytoplasmic side. SUBCELLULAR LOCATION: [Isoform 11]: Myelin membrane; Peripheral membrane protein; Cytoplasmic side. SUBCELLULAR LOCATION: [Isoform 10]: Myelin membrane; Peripheral membrane protein; Cytoplasmic side. SUBCELLULAR LOCATION: [Isoform 9]: Myelin membrane; Peripheral membrane protein; Cytoplasmic side. SUBCELLULAR LOCATION: [Isoform 8]: Myelin membrane; Peripheral membrane protein; Cytoplasmic side. SUBCELLULAR LOCATION: [Isoform 7]: Myelin membrane; Peripheral membrane protein; Cytoplasmic side. SUBCELLULAR LOCATION: [Isoform 6]: Myelin membrane; Peripheral membrane protein; Cytoplasmic side. SUBCELLULAR LOCATION: [Isoform 5]: Myelin membrane; Peripheral membrane protein; Cytoplasmic side. SUBCELLULAR LOCATION: [Isoform 4]: Myelin membrane; Peripheral membrane protein; Cytoplasmic side. SUBCELLULAR LOCATION: [Isoform 3]: Cytoplasm. Nucleus. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. Nucleus. SUBCELLULAR LOCATION: [Isoform 1]: Cytoplasm. Nucleus.
Protein: ISPG_YERPS
Sequence: MHNGSPIIRRKSTRIYVGKVPIGDGAPIAVQSMTNTKTTDVDATVAQIKALERVGVDIVRVSIPTMDAAEAFKLIKQQSTVPLVADIHFDYRIALKVAEYGVDCLRINPGNIGNESRIREVVACARDYNIPIRIGINGGSLEKDIQEKYGEPTPEALLESAMRHVDILDRLNFDQFKVSVKASDVFLAVNSYRLLAKQINNPLHLGITEAGGARSGSVKSAIGLGLLLSEGIGDTLRISLAADPVEEVKVGFDILKSLRIRARGINFIACPTCSRQEFDVIGTVNALEQRLEDLITPMDVSIIGCVVNGPGEALVSTIGVTGARNHSGFYEDGVRQKERFDNKAMIDQLEAKIRAKASILDANNRIVINQLDDNK
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: SYK_BURCM
Sequence: MTEPTQTQPAVAADENQIIAERREKLRALREQGVAYPNDFRPTHHAADLQATFADSDKAALEANPVEVSVAGRMMLKRVMGKASFATVQDGSGQIQFFVTPNDVGAETYDAFKKWDLGDIVAARGVLFRTNKGELSVQCKELRLLSKALRPLPDKFHGLADQEMRYRQRYVDLIVTPETRDTFRARTRTIASIRKFMDNADFMEVETPMLHPIPGGAAAKPFVTHHNALDMQMFLRIAPELYLKRLIVGGFERVFEINRNFRNEGVSPRHNPEFTMMEFYAAYTDYRWLMDFTEQLIRQAAIDALGTATIQYQGRELDLAKPFHRLTITQAIQKYAPQYTDGQLSDDAFLRTELKRFGVDVSQPAFLNAGIGALQLALFEETAESQLWEPTYIIDYPVEVSPLARASDTTPGITERFELFMTGREIANGFSELNDPEDQAARFKKQVEQKDAGDEEAMFFDADYIRALEHGMPPTGGCGIGIDRLVMLLTDSPTIRDVLLFPHLRRED
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.