PharMolix/UniProtQA huggingface dataset:
Protein: E75_MANSE
Sequence: MTLVMSPDSSYGRYDAPTPTDVTSPVHREREPELHIEFDGTTVLCRVCGDKASGFHYGVHSCEGCKGFFRRSIQQKIQYRPCTKNQQCSILRINRNRCQYCRLKKCIAVGMSRDAVRFGRVPKREKARILAAMQQSSTSRAHEQAAAAELDDAPRLLARVVRAHLDTCEFTRDRVAAMRARARDCPTYSQPTLACPLNPAPELQSEKEFSQRFAHVIRGVIDFAGLIPGFQLLTQDDKFTLLKSGLFDALFVRLICMFDAPLNSIICLNGQLMKRDSIQSGANARFLVDSTFKFAERMNSMNLTDAEIGLFCAIVLITPDRPGLRNVELVERMHTRLKACLQTVIAQNRPDRPGFLRELMDTLPDLRTLSTLHTEKLVVFRTEHKELLRQQMWSEEEAVSWVDSGADELARSPIGSVSSSESGEAVGDCGTPLLAATLAGRRRLDSRGSVDEEALGVAHLAHNGLTVTPVRQPPRYRKLDSPTDSGIESGNEKHERIVGTGSGCSSPRSSLEEHNEDRRPPVSADDMPVLKRVLQAPPLYGGTPSLMDEAYRRHKKFRALRRDTGEAEARTVRPTPSPQPQHPHPANPAHPAHSPRPQRASLSSTHSVLAKSLMEGPRMTPEQLKRTDIIQQYMRRGESSAPAEGCPLRAGGLLTCYRGASPAPQPVLALQVDVTDAPLNLSKKSPSPPRTYMPQMLEA
What is the function of this protein?
Implicated in the regulation of ecdysone-triggered gene hierarchies.  Probably plays a key role in mediating the regulation of the larval molt by 20-OH-ecdysone.
What are the official names of this protein?
Ecdysone-inducible protein E75, Nuclear receptor subfamily 1 group D member 3.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: HEMTM_SIPNU
Sequence: MGFPIPDPYVWDESFKVFYQLLDDKHKQIFQGVFDCAKDPSSAAKLQKLIEVTAKHFSDEENMMQQSKYSGYPPHKKAHEEFLGKLRGLRAPLDTAGLDYCKDWLVQHIKTIDFKYKGKL
What is the function of this protein?
Myohemerythrin is an oxygen-binding protein found in the retractor muscles of certain worms.  The oxygen-binding site contains two iron atoms (By similarity).
What are the official names of this protein?
Myohemerythrin, MHr, myoHr.
What is the protein family that this protein belongs to?
Belongs to the hemerythrin family.
Protein: HEM3_CAMC5
Sequence: MKILKIATRKSALALWQSEHIKARLMAQHAGLQVELVGMKTKGDVILDTPLAKIGGKGLFTKELEDSMLSGQTHIAVHSLKDVPVAFLDGLVLAAICSREDVRDAMISQRYVKFDDLPQSAKVGTTSLRRKMQLLRMRPDLNIISLRGNVQTRLRKLKEGEFDAIILAMAGINRLNLADEVAHIYPFDIAQMTPAMGQGALGVEAVDDAQILEKIKFLNDERSVIETRVERDFVTLLEGGCQVPIGINARLASEEIEINAIVGLPDGSEVITENLTAKKSEFESVGKELAREFIARGAKELLKRAEEMANL
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: TM208_HUMAN
Sequence: MAPKGKVGTRGKKQIFEENRETLKFYLRIILGANAIYCLVTLVFFYSSASFWAWLALGFSLAVYGASYHSMSSMARAAFSEDGALMDGGMDLNMEQGMAEHLKDVILLTAIVQVLSCFSLYVWSFWLLAPGRALYLLWVNVLGPWFTADSGTPAPEHNEKRQRRQERRQMKRL
What is the function of this protein?
May function as a negative regulator of endoplasmic reticulum-stress induced autophagy.
What are the official names of this protein?
Transmembrane protein 208.
What is the protein family that this protein belongs to?
Belongs to the TMEM208 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: GLGA_ENT38
Sequence: MQVLHVCSEMFPLLKTGGLADVLGALPAAQIAEGIDTRVLLPAFPDIRRGIPDAQVVSRRDTFAGRITLLFGHYNGVGIYLIDAPHLYDRPGSPYHDTNLFAYTDNVLRFALLGWVGAEMATGLDPFWRPDIVHAHDWHAGLAPAYLAARGHPAKSVFTVHNLAYQGMYYAHHMNEIDLPWSFYNMHGLEFNGQISFLKAGLYYADHITAVSPTYAREITEPEFGYGMEGLLRQRQREGRLTGILNGVDEKIWNPETDLLLASRFSRDSVEDKAENKRQLQVAMGLKVNDKVPLFAVVSRLTSQKGLDLVLEALPGLLEQGGQLALLGAGDPVLQEGFLAAAAEHPGQVGVQIGYHEAFSHRLMGGSDVILVPSRFEPCGLTQLYGLKYGTLPLVRRTGGLADTVSDTSLENLADGIATGFAFEDSNAWSLLRAIRRAFVLWSRPSLWRFVQRQAMAMDFSWHVAAQSYRDLYQRLKS
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: MRAY_OPITP
Sequence: MLSHLADLQDYFGPLRLLRYITVRTLLAAVTSLTIGFVIAPWLIAKFRELKLGHGYIDDRTGALGATYFDKKNTPTMGGLIIFLSVFTSAALWAAPNIWVFVSLFVYAALTIPGWRDDYLKVVHKNRNGISSWEKIGWQSLATVVALGLLLWHPASAQKIREFWVPFVKYPLIPHMHWAVLLVLIYLWIVGFSNAINLTDGLDGLAIGCTIPVALVFGIMAYVADHVFLSQYLLTSHVPGTGELAVICGALIGGCMAFLWYNCHPAEVFMGDTGSLALGGLIGVMAFMIHQPLTLVIVGGVFVAEMLSVVVQVGVFKITKRRSGVGRRFFLMAPVHHHFQKKGWPETKVVLRFWVLSLGCALAGLATLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PMP15_CHLPN
Sequence: MRFFCFGMLLPFTFVLANEGLQLPLETYITLSPEYQAAPQVGFTHNQNQDLAIVGNHNDFILDYKYYRSNGGALTCKNLLISENIGNVFFEKNVCPNSGGAIYAAQNCTISKNQNYAFTTNLVSDNPTATAGSLLGGALFAINCSITNNLGQGTFVDNLALNKGGALYTETNLSIKDNKGPIIIKQNRALNSDSLGGGIYSGNSLNIEGNSGAIQITSNSSGSGGGIFSTQTLTISSNKKLIEISENSAFANNYGSNFNPGGGGLTTTFCTILNNREGVLFNNNQSQSNGGAIHAKSIIIKENGPVYFLNNTATRGGALLNLSAGSGNGSFILSADNGDIIFNNNTASKHALNPPYRNAIHSTPNMNLQIGARPGYRVLFYDPIEHELPSSFPILFNFETGHTGTVLFSGEHVHQNFTDEMNFFSYLRNTSELRQGVLAVEDGAGLACYKFFQRGGTLLLGQGAVITTAGTIPTPSSTPTTVGSTITLNHIAIDLPSILSFQAQAPKIWIYPTKTGSTYTEDSNPTITISGTLTLRNSNNEDPYDSLDLSHSLEKVPLLYIVDVAAQKINSSQLDLSTLNSGEHYGYQGIWSTYWVETTTITNPTSLLGANTKHKLLYANWSPLGYRPHPERRGEFITNALWQSAYTALAGLHSLSSWDEEKGHAASLQGIGLLVHQKDKNGFKGFRSHMTGYSATTEATSSQSPNFSLGFAQFFSKAKEHESQNSTSSHHYFSGMCIENTLFKEWIRLSVSLAYMFTSEHTHTMYQGLLEGNSQGSFHNHTLAGALSCVFLPQPHGESLQIYPFITALAIRGNLAAFQESGDHAREFSLHRPLTDVSLPVGIRASWKNHHRVPLVWLTEISYRSTLYRQDPELHSKLLISQGTWTTQATPVTYNALGIKVKNTMQVFPKVTLSLDYSADISSSTLSHYLNVASRMRF
What are the official names of this protein?
Probable outer membrane protein pmp15, Polymorphic membrane protein 15.
What is the protein family that this protein belongs to?
Belongs to the PMP outer membrane protein family.
What are the subcellular locations of this protein?
Secreted, cell wall. Cell outer membrane; Peripheral membrane protein; Extracellular side.
Protein: Y1232_METJA
Sequence: MELTVVQREILQELINLYREKNRPIKGTEIALRLNRNPGTIRNQMQALRALDLVDGVPGPKGGYVPTSKAYRALGLEDEGEIIVPIYKDGKKVEGVKVVKIEFDTVSHEKCCSSKIHIEGDTKHFNIGDIIRVGPTYHNKIIINGKIIGRDDIHRILLIDVLGVSSIPNIKVGDVGIKEVWTINPNCTLRETAKLFAEKYISGAPVVDNDKLVGVISLHDIAENIDNIDKKVKEVMRRDVITIHKDEKIYDALKIMNKNNVGRLVIVDDNNKIVGIITRTDILKIISGKFPENFHT
What are the official names of this protein?
Uncharacterized protein MJ1232.
Protein: FSA_SALHS
Sequence: MELYLDTANVAEVERLAHIFPIAGVTTNPSIVAASKESIWDVLPRLQNAIGEEGTLFAQTMSRDAKGMVEEAKRLNNAIPGIVVKIPVTAEGLAAIKLLKKEGIVTLGTAVYSASQGLLAALAGAKYVAPYVNRVDAQGGDGIRMVQELQTLLEHHAPDSMVLAASFKTPRQALDCLLAGCQAITLPLDVAQQMLNTPAVESAIEKFEQDWKNAFGNLNL
What is the function of this protein?
Catalyzes the reversible formation of fructose 6-phosphate from dihydroxyacetone and D-glyceraldehyde 3-phosphate via an aldolization reaction.
What are the official names of this protein?
Fructose-6-phosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_KOSOT
Sequence: MSKVCEICGKRPTTGNTVSHSNKKNKRWWKPNVQKVKVIVDGEVKKMRVCTKCLKAGKVQRAV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: PDXT_MYCTO
Sequence: MSVPRVGVLALQGDTREHLAALRECGAEPMTVRRRDELDAVDALVIPGGESTTMSHLLLDLDLLGPLRARLADGLPAYGSCAGMILLASEILDAGAAGRQALPLRAMNMTVRRNAFGSQVDSFEGDIEFAGLDDPVRAVFIRAPWVERVGDGVQVLARAAGHIVAVRQGAVLATAFHPEMTGDRRIHQLFVDIVTSAA
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: MUTS_MARMM
Sequence: MNAMSTLPVPRDRTFPSSEGATPMMQQFLELRAQAPADALLFYRMGDFYELFFDDAVRASAALDIALTKRGEHQGEPISMCGVPAATAEAYLARLIKAGFKVAVGEQMEDPKTAKARGGSKAVVRRAITRVVTPGTLTEDSLLDPRVSNRIAALAQLVTGEAALAWADVSTGDFRVSPVATENLAAEIAAMSPAELLVEERGFAEAAMLAPRSTLTPLPKAKFDPSSAERQLKDQFRVQELTAFGNFTKAECAALGALLDYLSLSQAGAPAKLAPPRQVAAGACLAIDPATRASLEIERTLSGSRQGSLLDAIDRTVTAPGARKLAERLARPLTNVAEIEARLDAIAWFERARPERRDLRDRLRQAGDAERALSRLLLGRGGPRDLKSLAAALQEGEIIASRLLDRTLDTPPTLISEGLEALVLGDKPELAELIAELERAIVDEPPLLARDGGFIAEGWQVELDELRQLRDASRRVVAGLQQTYAEAVGVSALKIKHNNVLGYFVEVTAKHGDALMGDDRFIHRQTMANAIRFSTTELAELEAKIASAGDRALAMEIDAFAGLRDRVEAQADLIRGAARALAEFDVAASLAEWAEDSEAARPVMSQDSVFHIEGGRHPVVERALAKAGDGRFTPNDCHLDGAGEEAKRLTFVTGPNMAGKSTFLRQNALILMLAQAGCYVPARAARIGVADRLYSRVGAADDLARGRSTFMAEMIETAAILNQATARSFVILDEIGRGTATFDGLSIAWAAAEHLHAVNGCRALFATHYHELTRLADDLDAAGNVSLKAREWKGELVFLHEVGSGAADRSYGIEVARRAGLPRVSVKRAQAILARLEADGAPAAALTDLPLFALSEPEPEPVISEVETRLGEIDPDALSPREALEVLYALKAMTKKT
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: CINAL_ACAM1
Sequence: MSRSAEVICVGTELLLGEVLNSNAQFLGQELARLGIAHFHQTVVGDNPTRIKRAIALACQRSQLLIFTGGLGPTPDDLTTETLADFFQAPLVNHPEILEDIARKFAQRNRVPSPSNDKQALLPDGAQILPNPIGSAPGIIWHPRPELTIFTFPGVPKEFHRMWQETAVPYLQSTGWVTAQIYSRVLRFWGIPESTLADQVAPLLALTNPTVAPYASKGQARLRISTRATSQETAHQVIAPIEQQIRQICGLHCFGGDDETLESVVGKLLQQRGETLAVAESCTGGGLGQRITGVSGSSTYFLGGVISYTNAAKRDLLKVNAADLEQYGAVSAIVAEQMAAGVRSQLHSTWGISITGIAGPDGGSETKPVGLVYIGLSGPQGTQSFEYQISPLRGRDWIRQMSTSHALDRLRRQLLADES
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: APOA1_ACIJB
Sequence: MKAVVLTLAVLFLTGSQARHFWQQDDPQSPWDRVKDLVTVYVDAVKDGGREYVAQFEASALGKQLNLKLLDNWDTLGSTVTKLREQIGPVTQEFWDNLEKETEVLRQEMSKDLEEVKQKVQPYLDDFQKKWQEEVELYRQKVAPLGTELREGARQKLQELHEKLSPLGEELRDRARTHVDALRAQLAPYSDELRERLAARLQALKESGGASLAEYHAKASEHLSTLSEKAKPALEDLRQGLLPVLESFKVGLMAIVDEATKKLNAQ
What is the function of this protein?
Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT).  As part of the SPAP complex, activates spermatozoa motility.
What are the official names of this protein?
Apolipoprotein A-I, Apo-AI, ApoA-I, Apolipoprotein A1.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted.
Protein: BCP1_BRACM
Sequence: MGRQNVVVVFGLVFLAVLGLAAAASSPSPSASPSKAPSTSTPEVEAPVSEDTIGTTDDDAAASPGDDDVAVAGPLGSDSSYGSNGPSGSADSADSGAAALGVSAVVVGVTSIVGSFLFF
What is the function of this protein?
Required for pollen fertility and development.  Active in both diploid tapetum and haploid microspores (By similarity).  Major pollen protein.
What are the official names of this protein?
Anther-specific protein BCP1.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: HES1_HUMAN
Sequence: MPADIMEKNSSSPVAATPASVNTTPDKPKTASEHRKSSKPIMEKRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNLQRAQMTAALSTDPSVLGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHLANCMTQINAMTYPGQPHPALQAPPPPPPGPGGPQHAPFAPPPPLVPIPGGAAPPPGGAPCKLGSQAGEAAKVFGGFQVVPAPDGQFAFLIPNGAFAHSGPVIPVYTSNSGTSVGPNAVSPSSGPSLTADSMWRPWRN
What is the function of this protein?
Transcriptional repressor of genes that require a bHLH protein for their transcription.  May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1.  Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity).  May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage.
What are the official names of this protein?
Transcription factor HES-1, Class B basic helix-loop-helix protein 39, bHLHb39, Hairy and enhancer of split 1, Hairy homolog, Hairy-like protein, hHL.
What are the subcellular locations of this protein?
Nucleus.
Protein: CSN6_XENLA
Sequence: MAAAASNGNGMEVDVAALPSVMAQGVTGSVTVALHPLVILNISDHWIRMRSQEGRPMQVIGALIGKQEGRNIEVMNSFELLSQINDEKITINKEYYYTKEEQFKQVFKDMEFLGWYTTGGTPDPSDIHVHKQVCEIIESPLFLKLNPMTKHTDLPVSVYESVIDIVNGEATMLLAELSYTLATEEAERIGVDHVARMTATGSGENSTVAEHLIAQHSAIKMLHSRVRLILEYVRAAEGGEVPFNHEILREASALCHCLPVLSTDKFKTDFYDQCNDVGLMSYLGTITKTCNTMNQFVNKFNILYDRQGIGRRMRGLFF
What is the function of this protein?
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity).  The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of E3 ligase complexes, leading to modify the Ubl ligase activity (By similarity).
What are the official names of this protein?
COP9 signalosome complex subunit 6, Signalosome subunit 6.
What is the protein family that this protein belongs to?
Belongs to the peptidase M67A family. CSN6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PCCB_MOUSE
Sequence: MAAAIRIRAVAAGARLSVLNCGLGITTRGLCSQPVSVKERIDNKRHAALLGGGQRRIDAQHKRGKLTARERISLLLDPGSFMESDMFVEHRCADFGMAADKNKFPGDSVVTGRGRINGRLVYVFSQDFTVFGGSLSGAHAQKICKIMDQAITVGAPVIGLNDSGGARIQEGVESLAGYADIFLRNVTASGVIPQISLIMGPCAGGAVYSPALTDFTFMVKDTSYLFITGPEVVKSVTNEDVTQEQLGGAKTHTTVSGVAHRAFDNDVDALCNLREFFNFLPLSSQDPAPIRECHDPSDRLVPELDTVVPLESSKAYNMLDIIHAVIDEREFFEIMPSYAKNIVVGFARMNGRTVGIVGNQPNVASGCLDINSSVKGARFVRFCDAFNIPLITFVDVPGFLPGTAQEYGGIIRHGAKLLYAFAEATVPKITVITRKAYGGAYDVMSSKHLLGDTNYAWPTAEIAVMGAKGAVEIIFKGHQDVEAAQAEYVEKFANPFPAAVRGFVDDIIQPSSTRARICCDLEVLASKKVHRPWRKHANIPL
What is the function of this protein?
This is one of the 2 subunits of the biotin-dependent propionyl-CoA carboxylase (PCC), a mitochondrial enzyme involved in the catabolism of odd chain fatty acids, branched-chain amino acids isoleucine, threonine, methionine, and valine and other metabolites.  Propionyl-CoA carboxylase catalyzes the carboxylation of propionyl-CoA/propanoyl-CoA to D-methylmalonyl-CoA/(S)-methylmalonyl-CoA (By similarity).  Within the holoenzyme, the alpha subunit catalyzes the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain, while the beta subunit then transfers the carboxyl group from carboxylated biotin to propionyl-CoA (By similarity).  Propionyl-CoA carboxylase also significantly acts on butyryl-CoA/butanoyl-CoA, which is converted to ethylmalonyl-CoA/(2S)-ethylmalonyl-CoA (By similarity).  Other alternative minor substrates include (2E)-butenoyl-CoA/crotonoyl-CoA (By similarity).
What are the official names of this protein?
Propionyl-CoA carboxylase beta chain, mitochondrial, PCCase subunit beta, Propanoyl-CoA:carbon dioxide ligase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RPOC_ERWT9
Sequence: MKDLLKFLKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLEKRQILTEEQYLDALEEFGDEFDAKMGAEAIQALLKNMDLEQECETLREELNETNSETKRKKLTKRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKMVEREESVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAERVYRAGLASLHARVKVRITEHEKNEQDEWVAKTSIIDTTIGRAILWMIVPKGLPYSIVNQALGKKAISKMLNTCYRILGLKPTVIFADQTMYTGFAYAARSGASVGIDDMVIPEKKVEIITEAEAEVAEIQQQFQSGLVTAGERYNKVIDIWAAANERVAKAMMENLSTEVVINRDGVEERQVSFNSIFMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDCGTHEGIMMTPVIEGGDVKEPLRERVLGRVTAEDVLKPGTADILLPRNTLLHEQQCDLLEEHSVDSLKVRSVVSCETDFGVCAHCYGRDLARGHIINKGEAIGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAESSIQVKNKGTLKLINAKSVTNSAGKLVITSRNVELKMIDEFGRTKESYKVPYGSTMAKGDGEQVAAGETVANWDPHTMPVITEVSGFIRFTDMIDGQTITRQTDDLTGLSSLVILDSAERTAGGKDLRPALKIVDANGNDVMIPGSDMPAQYFLPGKAIVQLEDGIKISSGDTLARVPQESGGTKDITGGLPRVADLFEARRPKEPAILAEISGIISFGKETKGKRRLVITPIDGSDHYEEMIPKWRQLNVFEGERVERGDVVSDGPESPHDILRLRGVHAVTRYITNEVQEVYRLQGVKINDKHIEVIVRQMLRKATIASAGSTDFLDGEQVEFSRVKIANRELEANGKISATFARDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRKAAGEAPVVPQVTADEASASLAELLNAGLGGRDDE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: RL28_GLAP5
Sequence: MSRVCQVTGKRPVVGNNRSHAMNATKRRFLPNLHTHRFWVESENRFVTLRLTAKGMRIIDKKGIDAVLAEIRARGEKI
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: KCNT1_RAT
Sequence: MARAKLPRSPSEGKAGPGDTPAGSAAPEEPHGLSPLLPTRGGGSVGSDVGQRLHVEDFSLDSSLSQVQVEFYVNENTFKERLKLFFIKNQRSSLRIRLFNFSLKLLTCLLYIVRVLLDNPDQGIGCWGCTKYNYTFNGSSSEFHWAPILWVERKMALWVIQVIVATISFLETMLLIYLSYKGNIWEQIFHVSFVLEMINTLPFIITVFWPPLRNLFIPVFLNCWLAKHALENMINDFHRAILRTQSAMFNQVLILFCTLLCLVFTGTCGIQHLERAGGNLNLLTSFYFCIVTFSTVGFGDVTPKIWPSQLLVVILICVTLVVLPLQFEELVYLWMERQKSGGNYSRHRARTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPSEMDVQVRRVLQIPLWSQRVIYLQGSALKDQDLMRAKMDNGEACFILSSRNEVDRTAADHQTILRAWAVKDFAPNCPLYVQILKPENKFHVKFADHVVCEEECKYAMLALNCICPATSTLITLLVHTSRGQEGQESPEQWQRMYGRCSGNEVYHIRMGDSKFFREYEGKSFTYAAFHAHKKYGVCLIGLKREENKSILLNPGPRHILAASDTCFYINITKEENSAFIFKQEEKQNRRGLAGQALYEGPSRLPVHSIIASMVAMDLQNTDCRPSQGGSGGGGGKLTLPTENGSGSRRPSIAPVLELADSSALLPCDLLSDQSEDEVTPSDDEGLSVVEYVKGYPPNSPYIGSSPTLCHLLPVKAPFCCLRLDKGCKHNSYEDAKAYGFKNKLIIVSAETAGNGLYNFIVPLRAYYRSRRELNPIVLLLDNKPDHHFLEAICCFPMVYYMEGSVDNLDSLLQCGIIYADNLVVVDKESTMSAEEDYMADAKTIVNVQTMFRLFPSLSITTELTHPSNMRFMQFRAKDSYSLALSKLEKQERENGSNLAFMFRLPFAAGRVFSISMLDTLLYQSFVKDYMITITRLLLGLDTTPGSGYLCAMKVTEDDLWIRTYGRLFQKLCSSSAEIPIGIYRTECHVFSSEPHDLRAQSQISVNMEDCEDTREAKGPWGTRAASGGGSTHGRHGGSADPVEHPLLRRKSLQWARKLSRKSSKQAGKAPMTTDWITQQRLSLYRRSERQELSELVKNRMKHLGLPTTGYEDVANLTASDVMNRVNLGYLQDEMNDHHQNTLSYVLINPPPDTRLEPNDIVYLIRSDPLAHVTSSSQSRKSSCSNKLSSCNPETRDETQL
What is the function of this protein?
Outwardly rectifying potassium channel subunit that may coassemble with other Slo-type channel subunits.  Activated by high intracellular sodium or chloride levels.  Activated upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1.  May be regulated by calcium in the absence of sodium ions (in vitro).
What are the official names of this protein?
Potassium channel subfamily T member 1, Sequence like a calcium-activated potassium channel subunit.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. KCa4.1/KCNT1 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRMD_METFK
Sequence: MSEASHLQERCARQFDVVTLFPEMFDALTKFGISARAQERGIYELALWNPRDFTTDNYRTIDDRPYGGGPGMVMLAEPLEKAIAAAKVRQQSRGVENPRVIHLSPQGVPLKHEHVMQLKDVPGLILLASRYEGVDERLLSTLVDEEYSIGDYVLSGGEIPAMAILDAIIRQLPGSLGDAGSAEEDSFADGLLDCPHYTRPEVYAGQKVPEVLLSGNHAKIKRWRLKQSLARTRARRPDLLAARPLTKEESRLLMEIEQEQDSHN
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HS701_ARATH
Sequence: MSGKGEGPAIGIDLGTTYSCVGVWQHDRVEIIANDQGNRTTPSYVAFTDSERLIGDAAKNQVAMNPVNTVFDAKRLIGRRFSDSSVQSDMKLWPFKIQAGPADKPMIYVEYKGEEKEFAAEEISSMVLIKMREIAEAYLGVTIKNAVVTVPAYFNDSQRQATKDAGVIAGLNVMRIINEPTAAAIAYGLDKKATSVGEKNVLIFDLGGGTFDVSLLTIEEGIFEVKATAGDTHLGGEDFDNRMVNHFVQEFKRKSKKDITGNPRALRRLRTSCERAKRTLSSTAQTTIEIDSLYEGIDFYSTITRARFEELNMDLFRKCMEPVEKCLRDAKMDKSTVHDVVLVGGSTRIPKVQQLLQDFFNGKELCKSINPDEAVAYGAAVQGAILSGEGNEKVQDLLLLDVTPLSLGLETAGGVMTTLIPRNTTIPTKKEQVFSTYSDNQPGVLIQVYEGERARTKDNNLLGKFELSGIPPAPRGVPQITVCFDIDANGILNVSAEDKTTGQKNKITITNDKGRLSKDEIEKMVQEAEKYKSEDEEHKKKVEAKNALENYAYNMRNTIQDEKIGEKLPAADKKKIEDSIEQAIQWLEGNQLAEADEFEDKMKELESICNPIIAKMYQGAGGEAGGPGASGMDDDAPPASGGAGPKIEEVD
What is the function of this protein?
In cooperation with other chaperones, Hsp70s are key components that facilitate folding of de novo synthesized proteins, assist translocation of precursor proteins into organelles, and are responsible for degradation of damaged protein under stress conditions (Probable).  Probably involved in defense response.  Chaperone involved in protein targeting to chloroplasts.  May cooperate with SGT1 and HSP90 in R gene-mediated resistance towards the oomycete Hyaloperonospora parasitica (downy mildew).  Plays a role with WPP-domain proteins in facilitating WIT1 nuclear envelope targeting (PubMed:12805626, PubMed:18065690, PubMed:19617588).  Modulates stomatal aperture in response to various environmental conditions and physiological responses to the hormone abscisic acid (ABA) (PubMed:21586649).
What are the official names of this protein?
Heat shock 70 kDa protein 1, Heat shock cognate 70 kDa protein 1, Heat shock cognate protein 70-1, AtHsc70-1, Heat shock protein 70-1, AtHsp70-1, Protein EARLY-RESPONSIVE TO DEHYDRATION 2.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 (TC 1.A.33) family. DnaK subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus.
Protein: THIM_STRA1
Sequence: MYLEQLKEVNPLTICITNNVVKNFTANGLLALGASPAMSECIEDLEDLLKVADALLINIGTLTKESWQLYQEAIKIANKNQVPVVLDPVAAGASRFRLEVSLDLLKNYSISLLRGNGSEIAALIGEKQASKGADGGKVADLESIAVKANQVFDVPVVVTGETDAIAVRGEVRLLQNGSPLMPLVTGTGCLLGAVLAAFIGSSDRSDDLACLTEAMTVYNVAGEIAEKVAKGKGVGSFQVAFLDALSQMKSEMIMDK
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: GLYC_MOUSE
Sequence: MADRDATLWASHEKMLSQPLKDSDAEVYSIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGGTEFIDELEMLCQKRALQAYHLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVYPETGYINYDQLEENASLFHPKLIIAGTSCYSRNLDYARLRKIADDNGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVRSVDPKTGKETYYELESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTTEFKIYQLQVLANCRALSDALTELGYKIVTGGSDNHLILMDLRSKGTDGGRAEKVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEEDFQKVAHFIHRGIELTLQIQSHMATKATLKEFKEKLAGDEKIQSAVATLREEVENFASNFSLPGLPDF
What is the function of this protein?
Interconversion of serine and glycine.
What are the official names of this protein?
Serine hydroxymethyltransferase, cytosolic, SHMT, Glycine hydroxymethyltransferase, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.