PharMolix/UniProtQA huggingface dataset:
Protein: ATL81_ARATH
Sequence: MYDLTFLLISLFPIDITLPTRQPQNKPFLLPQATYETSHNISDPAVSLHGLKMSISTTETDNFKPVHTLVSSPVTIVLTGSLLFIIFTGFFSFFFCGCLFRKLMRIWNNHRNRNRPSNLIQPSNPPENLGLDSKIIESFPEYPYSVKDHGTDQCSICLTEFMDDDTIRLISTCNHSFHTICIDLWFEGHKTCPVCRRELDVEDRTSLEKPLEVPEIDLVRSEIHDEPLPRDTVTIIVHEEHPSTTIGSLEHTDEIESYERRMKASNLRFWRSHSTGHSIVVKTENEQEEEEEEEKDEIKIRIEISGECQFEDHKMTLPNRKLYCVRGTYSVG
What are the official names of this protein?
RING-H2 finger protein ATL81, RING-type E3 ubiquitin transferase ATL81.
What is the protein family that this protein belongs to?
Belongs to the RING-type zinc finger family. ATL subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RTEL1_ARATH
Sequence: MGFTVVSRSGSPTRRENQKRRVCFRLLLRLLRRGFVVLSAESDPKMPNYSIRGINVEFPFEAYQSQIIYMDRVIESLQNKCHALLESPTGTGKTLCLLCATLAWRKSLGSFSTRKDRKNSAIPWSDSDEPLSQSGGGGGGAFPTIVYASRTHSQLRQVIKELKRSSYRPKMVVLGSREQLCVNEEVNSLRGKALTNACQYLCKKRGKRQCNHFNRLPDYLKHNPHIGDEPVDIEDLVNIGKDSGPCPYYITRELHKDVDIIFAPYNYLISNGYRKFLKVNWTNSVLIFDEAHNLESLCADSASFDLPSVLLSACISEAQECVQLAAARRDSLNDVSINPENFAILKGLLLKLQELISKVPIPKRDEGFTKPGPYIYEMLKSLNITHETAPKLIGTVEEAAVFLEEEKQRTATNAGSKLEIIADMLKLIFRENGSNHADVYRVHVQELEQNSTDVMKGKVSRTLSWWCFSPGITMLDIAQKGVGSIILTSGTLSPMDSLAQELKLDFPIRLENPHVISSNQLWAGVVSTGPSGYVLNSSYRNRDVPEYKQELGNAIVNFSRVVPEGLLIFFPSYYLMDSCITFWKNGCYRNSMTVWERICKLKKPVIEPKDSSLFPAAMRDFSEKLQDRATSGVVFFAVCRGKVSEGLDFADGAGRAVVITGLPYARVTDPRVKLKREFLDEQSQLADVKLPRSTLLSGSMWYSQEAARAVNQAIGRVIRHRHDYGAIIFCDDRFEQPSQQSKISLWIRPNVKCYSRYGEVISDLARFFRTERSNFPARLVTEQENNIVSTLLPVESIEDNPTPAFGNSNLKNVGVAQNELSRLEAFPPANRASPLERDGNNVKRNGLTILKHTGKIPRIVKGDVMQGCSSRKAKLVELSDDEETPVERRCEVVDLESDNCETQTCVTEVLASSTCLNTMGLKKKRKVPESQGSASSSVLTAKGNGGGDKKEASASAFLSQVKEKLNTEEYKKFIGYMQALKKKEIKLANVMQSIVQLFCGSERDHLLMGFKDFVPVKYRPAYEECIKTRKRQSIIFGNSN
What is the function of this protein?
ATP-dependent DNA helicase implicated in DNA replication, DNA repair and the maintenance of genomic stability.  Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis.  Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates (PubMed:25516598, PubMed:25595823).  Also plays a role in preserving the stability of 45S rDNA repeats (PubMed:27760121).
What are the official names of this protein?
Regulator of telomere elongation helicase 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the helicase family. RAD3/XPD subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: FABH2_BACCR
Sequence: MHSKSRITAIGTYVPDQILSNNDLEKMVHTNDEWIVQRTGMRERRIASEEEYSSNLAIKAIENLCTTYKKNLEDVDCIIVATTTADYVFPSVACQIQQYFNIPHTLAFDLNATCAGFTYGLHVGNSLITSESHEKVLVVATETLSKVTDYTDRTTCILFGDGAGAILLERDENTPSFIAAHMGTNGDGGIHLYRTNLSTTMNGTPLQTNEKIVQNGREVYKWATRTVPKGIKNLLHTVNMQVDDIDWFIPHSANLRMIESICEKSQIPIQKTLTSVEYMGNTSSVTIPLALNLAIKEGKLNNGDTLLLYGFGGGLTHLGLIVEWNLI
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III 2, Beta-ketoacyl-ACP synthase III 2, KAS III 2, 3-oxoacyl-[acyl-carrier-protein] synthase 3 2, 3-oxoacyl-[acyl-carrier-protein] synthase III 2.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTPPA_NITWN
Sequence: MSGRPKLVLASGSPRRLSLLNQAGIEPDALRPVDIDETPTKGELPRACANRLARAKADAALRALQIDDELRGSFILAADTVVAVGRRILPKADLVDEASQCLRLLSGRNHRVYTAVCLVTPKENFRQRLVETRVRFKRLSEEDIQAYIGSGEWRGKAGGYAIQGIAGSFVVKLVGSYTNVVGLPLNESIALLGGEEFPIRAGWLDAG
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRM5_COPC7
Sequence: MTTRHLYLDTSPPAYTGSRTELDKSAFHKTLPVLAVRVRPEKVGKFLKGDAMKRALLDIPKVRTVVSDPKEEGNRLVLLRMPNEGDIPPEALELIKTESNGLTEFNVNLDYNYWTADEILQSFLPEELREGAPSGFAMVGHIAHLNLNEEYLPYKYIIGQLILEKNNRVRTVVNKINSIDTQFRFFKMELLAGEPDYVVEHHESDCRFMFDFTKVYWNSRLHTEHDRLIQVFQPEEVVADVFAGVGPFAIPAGKKGCGVLANDLNPESYKYLAINAKNNRVDDTVKAFCEDGREFIQKSVSRLWEEPLPAYTGPKQSRVQEEKERRRLQRLKAEGQTVPIPPSEKQHGRRRISHFVMNLPDSAISFLDAFRGLLSGAEPALREQYSTMPMVHCHCFTREVDSRVNAEGDIRKRVEEKLGGALTSETSFHFVRSVAPNKDMYCISFRLPPEVAFGERM
What is the function of this protein?
Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs.  Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside.  This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.
What are the official names of this protein?
tRNA (guanine(37)-N1)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase, tRNA methyltransferase 5.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Nucleus. Cytoplasm. Note=Predominantly in the mitochondria and in the nucleus.
Protein: RLMKL_SHESH
Sequence: MLNFFAAAPRGYEYALSLELADLGASEIKESVAGVYFSASLELGYRITLWSRIASRIILVIHKGPCESPEQLYNAAYGIDWQMEFNHRSTFSIDFHGMGGFINNTMFGALKIKDAIVDRFRDDDCPRPDVARVDADFRIDAHYRRGQITIGLNFSGPALHKRGYRSTTGEAPLKENLAANMLVRSGWQKTPVTLMDPFCGSGTILIEAAMIACDMAPGLHRERFGFEHWHRHNDKVWQGLLDEAKARASIGKTRCTTKFYGSDIDSRLVALAKRNAENAGVLDLIEFDVSNALNVKVPGESGYLISNPPYGERLGTVTALLQLYYQLGDKFKAEFGGWNLAILNSDVELLSALKLKADKQMKMNNGALECAFNLYTVHAENTRRVDPSKINRDGDVSDIAVPFANRVKKNFKQLQKWAKKEGVDSYRIYDADLPDYKVAIDKYLDYVVIQEYTAPVDIPESVTKRRLTDVLITLPSAIGIDPENIILKTRERQKGTNQYEKIQANKLELITTEYGAKFKLNLKEYLDTGLFLDHRLTRKLVGQKSKDKDVLNLFAYTGTASVHAALGGAKSVKTVDMSNTYTNWAKENFALNGLNDDKYQFVQANCMQWIKTTHDKFDLIFIDPPTFSNSKRMEDSFDVLRDHVALLSSLIKLLNPGGEIIFSNNKRKFKMEIEALEALNFTVKNIDNQTLPLDFKRNPQIHNTWLLTHAE
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_BARHE
Sequence: MQLYDVVVIGGGHAGCEAAYASARAGAQTALITHKISALGTMSCNPAIGGLGKGHLVREIDAFDGLMGRAADAAGIQFRLLNRRKGPAVRGPRAQADRQLYKEAIQKLLQKQDNLILIEDEVIDLIVKDKSISGVILKKQGILPSGAVVLTTGTFLNGFIHIGDKTWAAGRMGEQSSIKLAERLKSYGINLGRLKTGTPARLSKKTIRWECLPKQQADENPVPFSLLTEKIEQPQIECAITRTNAQTHQIIRENIHRSALYSGNIEGLGPRYCPSIEDKIVKFGERDGHQIFLEPEGLNDDTIYPNGLSTSLPEDVQVSLLKTIEGLENVTILQSGYAIEYDFVNPQQLTKTLELRSLPGLFLAGQINGTTGYEEAAAQGLLAGLNAARKVGGLDEILISRSTAYIGVMVDDLVSRGVCEPYRMFTSRAEFRLSLRSDNADARLTPLAQQLGIVSKLRWECYQKKQQRLDQARSLCQELFLTPNQASAHGLQVNHDGIRRSAYDLLAYPHMSIERLSHIWPQLQSIDSKTVESVEIEAQYAVYLEKQAQDILALQRDERLEIPSSLDVQAISGLSNELKTKIQKISPRSIADAQKIDGMTPAALSLIITYIQRQRREKAKSA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IKKB_HUMAN
Sequence: MSWSPSLTTQTCGAWEMKERLGTGGFGNVIRWHNQETGEQIAIKQCRQELSPRNRERWCLEIQIMRRLTHPNVVAARDVPEGMQNLAPNDLPLLAMEYCQGGDLRKYLNQFENCCGLREGAILTLLSDIASALRYLHENRIIHRDLKPENIVLQQGEQRLIHKIIDLGYAKELDQGSLCTSFVGTLQYLAPELLEQQKYTVTVDYWSFGTLAFECITGFRPFLPNWQPVQWHSKVRQKSEVDIVVSEDLNGTVKFSSSLPYPNNLNSVLAERLEKWLQLMLMWHPRQRGTDPTYGPNGCFKALDDILNLKLVHILNMVTGTIHTYPVTEDESLQSLKARIQQDTGIPEEDQELLQEAGLALIPDKPATQCISDGKLNEGHTLDMDLVFLFDNSKITYETQISPRPQPESVSCILQEPKRNLAFFQLRKVWGQVWHSIQTLKEDCNRLQQGQRAAMMNLLRNNSCLSKMKNSMASMSQQLKAKLDFFKTSIQIDLEKYSEQTEFGITSDKLLLAWREMEQAVELCGRENEVKLLVERMMALQTDIVDLQRSPMGRKQGGTLDDLEEQARELYRRLREKPRDQRTEGDSQEMVRLLLQAIQSFEKKVRVIYTQLSKTVVCKQKALELLPKVEEVVSLMNEDEKTVVRLQEKRQKELWNLLKIACSKVRGPVSGSPDSMNASRLSQPGQLMSQPSTASNSLPEPAKKSEELVAEAHNLCTLLENAIQDTVREQDQSFTALDWSWLQTEEEEHSCLEQAS
What is the function of this protein?
Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses (PubMed:30337470).  Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation.  Phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues.  These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome.  In turn, free NF-kappa-B is translocated into the nucleus and activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis.  In addition to the NF-kappa-B inhibitors, phosphorylates several other components of the signaling pathway including NEMO/IKBKG, NF-kappa-B subunits RELA and NFKB1, as well as IKK-related kinases TBK1 and IKBKE (PubMed:11297557, PubMed:20410276).  IKK-related kinase phosphorylations may prevent the overproduction of inflammatory mediators since they exert a negative regulation on canonical IKKs.  Phosphorylates FOXO3, mediating the TNF-dependent inactivation of this pro-apoptotic transcription factor (PubMed:15084260).  Also phosphorylates other substrates including NCOA3, BCL10 and IRS1 (PubMed:17213322).  Within the nucleus, acts as an adapter protein for NFKBIA degradation in UV-induced NF-kappa-B activation (PubMed:11297557).  Phosphorylates RIPK1 at 'Ser-25' which represses its kinase activity and consequently prevents TNF-mediated RIPK1-dependent cell death (By similarity).  Phosphorylates the C-terminus of IRF5, stimulating IRF5 homodimerization and translocation into the nucleus (PubMed:25326418).
What are the official names of this protein?
Inhibitor of nuclear factor kappa-B kinase subunit beta, I-kappa-B-kinase beta, IKK-B, IKK-beta, IkBKB, I-kappa-B kinase 2, IKK2, Nuclear factor NF-kappa-B inhibitor kinase beta, NFKBIKB, Serine/threonine protein kinase IKBKB.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Membrane raft. Note=Colocalized with DPP4 in membrane rafts.
Protein: HSF2_MOUSE
Sequence: MKQSSNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMASFVRQLNMYGFRKVVHIESGIIKQERDGPVEFQHPYFKQGQDDLLENIKRKVSSSKPEENKIRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHAQQQQVIRKIVQFIVTLVQNNQLVSLKRKRPLLLNTNGAPKKNLYQHIVKEPTDNHHHKVPHSRTEGLKSRERISDDIIIYDVTDDNVDEENIPVIPETNEDVVVDSSNQYPDIVIVEDDNEDEYAPVIQSGEQSEPAREPLRVGSAGSSSPLMSSAVQLNGSSSLTSEDPVTMMDSILNDNINLLGKVELLDYLDSIDCSLEDFQAMLSGRQFSIDPDLLVDLFTSSVQMNPTDNIKYTKSENKGLEATKSSVVQHVSEEGRKSKSKPDKQLIQYTAFPLLAFLDGNSASAIEQGSTTASSEVVPSVDKPIEVDELLDSSLDPEPTQSKLVRLEPLTEAEASEATLFYLCELAPAPLDSDMPLLDS
What is the function of this protein?
DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription.  In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked.  HSF2 is expressed in a form that binds DNA constitutively but loses DNA binding by incubation at greater than 41 degrees C.
What are the official names of this protein?
Heat shock factor protein 2, HSF 2, Heat shock transcription factor 2, HSTF 2.
What is the protein family that this protein belongs to?
Belongs to the HSF family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Cytoplasmic during normal growth and moves to the nucleus upon activation.
Protein: TRMD_CORJK
Sequence: MRLDVVTIFPEYLEPLRHALLGKAIEQGILSVGVHNLRAWTNDVHQSVDSTPCGGGPGMVMKPEVWGPALDDVAAGTGPAATVSDLESSAEHKRNLRPATTNGDAEPLGEKAGGVTKPLLIVPTPAGKPFTQDMAERWSTEEHVVFACGRYEGIDQRVVEDAHNRYRVEEVSIGDYVLIGGEVAVLVMAEAMVRLIPGVLGNQASHQEDSFQDGLLEGPSYTRPRQWRGLDVPDVLFSGNHAKIAQWRREQSLARTKKIRPDLLDSVELSKADRAYLDGLEL
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_KLEP7
Sequence: MQGSVTEFLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTLNKSGIGPVTAADITHDGDVEIVKPQHVICHLTDENAAISMRIKVQRGRGYVPASARIHSEEDERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETNGTIDPEEAIRRAATILAEQLEAFVDLRDVRQPEVKEEKPEFDPILLRPVDDLELTVRSANCLKAEAIHYIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLENWPPASIADE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: SURE_THEKO
Sequence: MRILVTNDDGIYSNGIRAAVKALSSLGEVYVVAPLFQRSASGRAMTLHRPIRARLVDVPGAKVAYGIDGTPTDSVIFALARFGDFDLAVSGINLGENLSTEITVSGTASAAIEAATHEVPSIAISLEVDWKKTLGEGEGIDFSVASHFLKRITRAVLEKGLPEGVDMLNVNVPSNATPETEIAITRLARKRYCPTIEERVDPRGHPYYWIVGQKREEFEPGTDAYALKIERKVSVTPINIDMTARVNFEEVRKVLFAQP
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2A25_CYRHA
Sequence: MKMTLIAILTCAAVLVLHTTAAEELEAESQLMEIGMPDTELEAVDEERLFECSVSCEIEKEGNKDCKKKKCKGGWKCKFNMCVKV
What is the function of this protein?
Neurotoxin active on both insects and mammals.
What are the official names of this protein?
U4-theraphotoxin-Hhn1a, U4-TRTX-Hhn1a, Hainantoxin-II.25, HNTX-II.25, Peptide F8-20.15.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 12 (Hwtx-2) family. 02 (Hwtx-2) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MSHB_GORB4
Sequence: MLLVHAHPDDETIMTGGTIARYLDEGVDVRVLTFTLGEEGEVIGDRWAQLVADGGADQLGGFRIGELTGALAALSPPGGSPVQPWFLGGAGRWRDSGMAGSAAARHPRALVNAGFDEPVGVLTDILESFAPQVVITYDSAGTYGHPDHKLVHEVTAAALARVAASRPEQIKVYESVTEHSALQAGLVAAARRVPDGWRMPGPGELPSYPDAMVTAEIDVRTQYDRKVAALAAHATQVTVAPSGTEYALSNNIVQPIFGHEHFIRVDAAAVAGPRETDLFDGIG
What is the function of this protein?
Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.
What are the official names of this protein?
1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase, GlcNAc-Ins deacetylase, N-acetyl-1-D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase.
What is the protein family that this protein belongs to?
Belongs to the MshB deacetylase family.
Protein: CHCH5_MOUSE
Sequence: MQAALEVTARYCSRELDQYGQCVAAKPESWHRDCHHLKMSIARCTSSHPIIRQIRQACAEPFEAFEKCLRLNEAAVGNCAEHMRRFLQCAEQVQPPSSPTTGEAQPLPAS
What are the official names of this protein?
Coiled-coil-helix-coiled-coil-helix domain-containing protein 5.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space.
Protein: MTNK_BACC2
Sequence: MGYYSLTEITAVQYAKDHGYFEAKANVVCHEIGDGNLNYVFKLDDGEKSIIIKQALPYAKVVGESWPLSIKRATIESKALQIFAQYVPDYVPAVYSHDEELAITVIEDLSRLTITRKGLIGGEEYPLLSQHIGRFLAHVLFYTSDFGLQSEEKRVLEGTFVNPDLCKITEDLVFTDPFGHYDTNDYEPDLQLVVDELWSDKTLKLKVAQYKYKFLTRKETLIHGDLHTGSIFSSPSETKVIDPEFATYGPFGFDIGQFIANLLLNALSREEEKRSVLFFHIEKTWSYFVETFTKLWIGEGVEVYTKEKQWLPIILQNIFTDAVGFAGCELIRRTIGLAHVADLDEIENKETRIQAKKQALSLGKELIKYESKSADIQLFRTLFQQTVSGGVKA
What is the function of this protein?
Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
What are the official names of this protein?
Methylthioribose kinase, MTR kinase.
What is the protein family that this protein belongs to?
Belongs to the methylthioribose kinase family.
Protein: CRR52_ARATH
Sequence: MSSVFGSVHILAMIAIQLLLTHSVSSLNLTNAYLHHKCSNTQGKYKQGSAFEKNLNLVLSTITSIGNFRDGFRYTEEGEDPNNVFVMFQCRGDSYWSKCPPCISTAVSGLRRRCPRNKGAIIWYDQCLLKISSVASFNKIDYENDFYLSNPNNMSDRGLFNKETSALLEKLAYKASDRNNLDGKQLVLYAAGEKRIGTKKVYAMVQCTKDLIFTKCFECLEGILRKFPQCCDGKRGGRVFGTSCNFRYELYPFLRN
What are the official names of this protein?
Cysteine-rich repeat secretory protein 52.
What is the protein family that this protein belongs to?
Belongs to the cysteine-rich repeat secretory protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: BEL3_FOAMV
Sequence: MEIGVMQLCNMLIRLKGAVKQGAWHHLYLTTKLCSFIEPLWQTSPILGLEKDILLMVTKQLWKLMDLREEVTRRGCGGMSLETRENKEESITGKEVKNLITQILLLLIDVPGMRDTRFLNCPHSLLPLTSNAELLKHCLMAGKWSPKAEMIILAAERSEH
What are the official names of this protein?
Protein Bel-3.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Expressed in low amounts in the cytoplasm of infected cells.
Protein: ARNE_SHISS
Sequence: MIWLTLVFASLLSVAGQLCQKQATCFVAINKRRKHIVLWLGLALACLGLAMVLWLLVLQNVPVGIAYPMLSLNFVWVTLAAVKLWHEPVSPRHWCGVAFIIGGIVILGSTV
What is the function of this protein?
Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
What are the official names of this protein?
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE, L-Ara4N-phosphoundecaprenol flippase subunit ArnE, Undecaprenyl phosphate-aminoarabinose flippase subunit ArnE.
What is the protein family that this protein belongs to?
Belongs to the ArnE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1570_FRAP2
Sequence: MAGHSKWANIKHKKAKEDAKRGKIFTKLIREITVAARLGGGDKDANPRLRAAIATAFANNMSKDTVERAILKGAGGDDSANVEEVRYEGYGPGGVAIIVDCMTDNRNRTVGEVRHAFTKSGGNLGTDGSVAYMFTKKGIISFAPGVDEDALMEVALEAGAEDIITHEDGSIDVFTTPHDFSDVQEALIAKGFNSDNAEVTFDAETKAELDIEIAEKVMNLIDRLEDLDDVQNVYSNVNFTQELMEQLG
What are the official names of this protein?
Probable transcriptional regulatory protein Fphi_1565.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEIS3_MOUSE
Sequence: MARRYDELRHYPGITEHTTALASFSEAAPSVPRAPGPYTPHRPPQLQAPGLDSDSLKREKDDIYGHPLFPLLALVFEKCELATCSPRDGASAGLGSPPGGDVCSSDSFNEDIAAFAKQIRSERPLFSSNPELDNLMVQAIQVLRFHLLELEKVHDLCDNFCHRYITCLKGKMPIDLVIEDRDGSCREDLEDYAASCPSLPDQNTTWIRDHEDSGSVHLGTPGPSSGGLASQSGDNSSDQGDGLDTSVASPSSAGEDEDLDLERRRNKKRGIFPKVATNIMRAWLFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRTGQGASFNPEGQPMAGFTETQPQVTVRTPGSMGMNLNLEGEWHYL
What is the function of this protein?
Transcriptional regulator which directly modulates PDPK1 expression, thus promoting survival of pancreatic beta-cells.  Also regulates expression of NDFIP1, BNIP3, and CCNG1.
What are the official names of this protein?
Homeobox protein Meis3, Meis1-related protein 2.
What is the protein family that this protein belongs to?
Belongs to the TALE/MEIS homeobox family.
Protein: DNLI_PYRAR
Sequence: MQFGELVKALAAVESTTQRSVMVKLLASLFKKALPEEIDKVIYLILGDLRPPWEGLELGVGEKLCLRALAKATGTSQAELESMYKKTGDIGEAARRALASSKRPGLLAFGSQKPLEVSEVYDALIKVARATGEGAQDMKIALLSSLFARSSPEEGKYIARFVVGKLRLGVADMTIIEALADAYGVRKEDLERAYHVYPDLGHLAKLVASGKPLDEVKVTPGVPVLPMLAQRLSSSSEILAKLGGAAICEYKYDGERAQIHISQSGVRIFSRRLEDITHAYPDVVKAVREAVSAREAILEGEIVAVDPDTGEMLPFQELMHRKRKHEVAAAMEMYPTVLYLFDIVYVDGEDLTNEPLIYRRVKLSEIVHESDKVQIAKWQMFDDPDTVDVFFHEAVSVGTEGLICKSPTSEYEMGARGWNWIKYKRDYKSEMIDTVDLVVVGAFYGRGKRAGLYGAFLLAAYDPSSDMFYTVCKVGSGFTDADLKKMYEILQPLKIPHRHPRVSSKMEADVWFVPQVVIEVIGAEITLSPLHTCCLGAVRPGVGLAVRFPRFTGRYRTDKGPEQATTVAEMLELYKRQKKVAQPE
What is the function of this protein?
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [ATP].
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
Protein: LYS5_CANGA
Sequence: MSDWLSLAKSNDPHIVVLTMDVHLSYFRDEYNFEEALRLLPFEWQCRVIQKRAHKDKVTALCNRLLQLYGCRLELNTQAIDFTQGKYGKPFVKNTESFNFSMTNGENFVSIIMANLFQTEVGIDLASINDFTSEGDLKIYEDVLSTEEYEKINNQTNLLDMKRLFAFYWSVKECYTKYLGVGLNGDLKIINVSLFSAPLINEAVSTFKLKDITFHSRWVSDNEILTYCFPAQYDFLKPIHAILNVVSVIEGIKTQFLT
What is the function of this protein?
Catalyzes the transfer of a 4'-phosphopantetheine moiety from coenzyme A to a serine residue of acceptor proteins, such as alpha-aminoadipate reductase.  Necessary for alpha-aminoadipate reductase activity (By similarity).
What are the official names of this protein?
L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase, AASD-PPT.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
Protein: RL30_STRFL
Sequence: MARLKITQTKSYIGSKQNHRDTLRSLGLKRLNDSVVKEDRPEFRGMVQTVRHLVTVEEVD
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: LTOR3_DROME
Sequence: MSDDIKKYLDGLLQKVSGLYVIQITDRDGVPLLRVSQEKNVDFALMPSFIPTFTTACDQASKLGLGRNKTIISMYSNYQVVQMNKLPLILTFVGAENCNTGHILALEHQVDGYLEDIKQAVTEA
What is the function of this protein?
Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids.  As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids.
What are the official names of this protein?
Ragulator complex protein LAMTOR3 homolog, Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3.
What is the protein family that this protein belongs to?
Belongs to the LAMTOR3 family.
Protein: EXO70_YEAST
Sequence: MPAEIDIDEADVLVLSQELQKTSKLTFEINKSLKKIAATSNQSSQLFTPILARNNVLTTLQRNIESTLNSVASVKDLANEASKYEIILQKGINQVGLKQYTQVVHKLDDMLEDIQSGQANREENSEFHGILTHLEQLIKRSEAQLRVYFISILNSIKPFDPQINITKKMPFPYYEDQQLGALSWILDYFHGNSEGSIIQDILVGERSKLILKCMAFLEPFAKEISTAKNAPYEKGSSGMNSYTEALLGFIANEKSLVDDLYSQYTESKPHVLSQILSPLISAYAKLFGANLKIVRSNLENFGFFSFELVESINDVKKSLRGKELQNYNLLQDCTQEVRQVTQSLFRDAIDRIIKKANSISTIPSNNGVTEATVDTMSRLRKFSEYKNGCLGAMDNITRENWLPSNYKEKEYTLQNEALNWEDHNVLLSCFISDCIDTLAVNLERKAQIALMPNQEPDVANPNSSKNKHKQRIGFFILMNLTLVEQIVEKSELNLMLAGEGHSRLERLKKRYISYMVSDWRDLTANLMDSVFIDSSGKKSKDKEQIKEKFRKFNEGFEDLVSKTKQYKLSDPSLKVTLKSEIISLVMPMYERFYSRYKDSFKNPRKHIKYTPDELTTVLNQLVR
What is the function of this protein?
Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis.  Plays a role in the assembly of the exocyst.
What are the official names of this protein?
Exocyst complex component EXO70, Exocyst complex protein of 70 kDa.
What is the protein family that this protein belongs to?
Belongs to the EXO70 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle. Bud. Bud neck. Note=Its polarization in the cell depends on EXO84.