PharMolix/UniProtQA huggingface dataset:
Protein: KUP_BRUSI
Sequence: MSGELNGNDTSAQAAVSAGSVLEGAAFADEGEQHNESMKTLVLGALGVVYGDIGTSPIYAFREALHAAATNGILARSDILGVVSLIFWALTLVVTVKYVLFVLRADNNGEGGILSLMALVRAALKGRPDLILGVGICGAALFFGDAVITPAISVLSAMEGLEIVAPNLTPFVVPATVVILVTLFSVQKLGTGRVAIVFGPIMALWFVALGASGLWHIFDDPTVMAALNPYYAVRFLTVSPAVAFVTVGAVFLAMTGAEALYADLGHFGRKPIVRAWLWIVFPCLLLNYFGQAAFILSHGEAAALPFFQMIPSFALWPMVLLATAATVIASQAVITGAYSVARQAVQLNILPRLEIQHTSEKLHGQIYIPRVNLLLGLAVVILVLGFEKSSNLAAAYGIAVTGNMLVTTVLLYIVMTRIWNWRVSRALPIILGFLVIDMLFFSANIIKVHEGGWASIGIATVLVLIMWTWVRGTRHLFQKTRKAEVPLDLIVEQMAKRPPTIVPGTAVFLTGDPKSAPTALMHSLKHYKVLHENNVILTVVTASKPWVASADRARLSQYNERFMLVTLTFGYMQQPNILRALGLCRRLGWKFDIMTTSFFLSRRSLKASVHSGMPLWQDKLFILLARTASDATEYFQIPTGRVVEIGTQVNI
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RNFD_MARN8
Sequence: MALVQQSSPHARRARPTSRVMLWVILAALPGLLAQTLFFGWGNLINVVWCIALALGSEAAFLKLRGKPVAFFLRDNTAAVTGLLLGLSLPQFTPWWVSGIAVVSAIVVAKQLYGGLGSNPFNPAMVGYALALISFPVAMTTNWAEAATLWGGAPGFGETLAKIFTGGQTAVDGWTMATPLDEYKHKIASHTSVEVLGHPTFGDLIARGWEWVNLAFLAGGVLLIALRIITWHIPVAFLAGIAAMSLAFGSNADQYAPLQLHLLAGGTMLGAFFIATDPVSAATSHQGKLIYGAGIGVLVYLIRSWGNYPDAVAFSVLLMNFAVPFIDHYTPPRTYGHHKARRGVPGRSGG
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit D, Rnf electron transport complex subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UXUA_SHIFL
Sequence: MEQTWRWYGPNDPVSLADVRQAGATGVVTALHHIPNGEVWSVEEILKRKAIVEDAGLVWSVVESVPIHEDIKTHTGNYEQWIANYQQTLRNLAQCGIRTVCYNFMPVLDWTRTDLEYVLPDGSKALRFDQIEFAAFEMHILKRPGAEADYTEEEIAQAAERFATMSDEDKARLTRNIIAGLPGAEEGYTLDQFRKHLELYKDIDKAKLRENFAVFLKAIIPVAEEVGVRMAVHPDDPPRPILGLPRIVSTIEDMQWMVDTVNSMANGFTMCTGSYGVRADNDLVDMIKQFGPRIYFTHLRSTMREDNPKTFHEAAHLNGDVDMYEVVKAIVEEEHRRKAEGKEDLIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAEVRGVELAIQRAFFSR
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.
What are the official names of this protein?
Mannonate dehydratase, D-mannonate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the mannonate dehydratase family.
Protein: RL32_BIFLD
Sequence: MALPKYKTSRANTHSRRANWKATAAATVNCPNCGAPALPHMACPSCGNYRGRTYRSAIQPAHTK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: ASSY_CHLPB
Sequence: MKREKIALAYSGGLDTSVMIKWLKDKYDADIIAVTGNLGQEKEIENLEQKAFDTGASGFSFLDLRKEFVENYIWPALKAGALYEEVYPLATALGRPLLAKALVDVALSEDCTMIAHGCTGKGNDQVRFEVTFASLAPHLKVLAPLREWEFNSREAEMAYAEKHGIPVSATKKSPYSIDENIWGISIECGVLEDPMVAPPEDAYQITTSPEKAPDNAAVIDIEFEQGVPVALDGRKMEGLDLIVELNKHGAAHGVGRLDMIENRVVGIKSREIYEAPAATILHFAHRELERLTLEKTVFQYKNTISQDYANLIYNGTWFSPMREALDGFVDATQKHVTGLVRVKLFKGSVTLLGRTSPWSLYNEELATYTEADTFNHKAAEGFIHLYGLGLKTYSEVQANNRK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACSA_DESAL
Sequence: MSNNLFTVPEDWQKRAWCDDARYQKMYDESVNDPDAFWSREAQRIDWFEPFSKVKNSSFNGDVDIKWFLDGKLNVAYNCLDRHLEKRGDQTAIIFEGNEPGVEEKITYRQLYERVCRFSNVLKSCGVKKGDRVSIYLPMIPQLAVAMLACARIGAIHSIVFAGFSPDALANRITDAECTILITADEGLRGPKAIGLKEAADEAMDKAGMVKKCIVVKHTGADVPMKAGRDLWWHELTAKESTECPPESMDSEDPLFILYTSGSTGTPKGVLHTTGGYIVYTSLTHQYVFDYHDGDIYWCTADIGWVTGHSYIIYGPLANGAVTIMFEGIPNYPDFSRFWQICDKHQVNIFYTAPTVVRALMQQGDEPVKATSRTSVRLLGTVGEPINPEAWLWYHRVVGEERCPIVDTWWQTETGGIMITPLPGATALKPGSATRPFFGIQPALIDKEGNQLEGPGEGYLVMLDSWPALARTVYGDHRRFKSTYFIQCPGTYFSGDGARRDEDGYYWITGRIDDVINVSGHRLGTAEIESSLVAHPAVSEAAVVGFPHDIKGQAIYAYVTLSSGYEPSEELRKELSLFVRKDIGPIATPEVLQFTDSLPKTRSGKIMRRILRKVACNELDNLGDTSTLADPAVVEALIKNRIDACR
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: HIS4_SHESM
Sequence: MIIPAIDLIDGKVVRLYQGDYGQQTTFDLSPLAQLQSYQDQGANWLHIVDLTGAKEPAKRQTTLIAKLTAGLSANIQVGGGIRTEEQVAELLSLGVKRVVIGSLAVKEPELVKGWFNKFGSEAICLALDVNINQSGEKIVAVSGWQSGGGKSLESIVEDFSQVGLKHALVTDISRDGTLTGANTELYRELSSRYPDIAWQASGGIATLEDVAAVRDSGAAGIIIGKALLINQFNVAEAIQCWPNE
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSBD_BACSU
Sequence: MGNDSVKDKMKGGFNKAKGEVKDKVGDMADRTDMQAEGKKDKAKGEIQKDIGKAKDKFSDKD
What are the official names of this protein?
Stress response protein CsbD.
What is the protein family that this protein belongs to?
Belongs to the UPF0337 (CsbD) family.
Protein: ITR3_MOMCH
Sequence: ERGCPRILKQCKQDSDCPGECICMAHGFCG
What is the function of this protein?
Inhibits trypsin.
What are the official names of this protein?
Trypsin inhibitor 3, MCTI-III, Trypsin inhibitor III.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I7 (squash-type serine protease inhibitor) family.
What are the subcellular locations of this protein?
Secreted.
Protein: ANFC2_TAKRU
Sequence: MAASSSSFVPLVLLFLAIPVEPRPSMTRDEAQVLRALFGARLSSIISTPVNTDDIAELLPRRPGPPRSFGASPGALRGLTRGSEGGSRFLLDFLQQQSKTTRRGRSSMVGGRGCFGMKIDRIGSISGLGC
What is the function of this protein?
Exhibits natriuretic and vasodepressant activity.  Has cGMP-stimulating activity.  May help to regulate body fluid homeostasis in a variety of aquatic environments.
What are the official names of this protein?
C-type natriuretic peptide 2.
What is the protein family that this protein belongs to?
Belongs to the natriuretic peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: IF1_NITHX
Sequence: MAKEELIQFEGLVTEILPDARYRVQLDAGHEIVAYTAGKMKKNRIKTLAGDRVTIEMSPYDLEKGRLIFRHKDERPSGAPRGGPPRGGQFRRR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCA_BACC0
Sequence: MERFKKASSIIETLKQQGHEAYFVGGSVRDLIIDRPIGDIDIATSALPEEVMAIFPRHVPVGLEHGTVIVVENGEPYEVTTFRTESEYEDFRRPSSVQFVRSLEEDLKRRDFTMNAIAMTEEGEMVDLFAGQEAIQKREIVTVGNAADRFQEDALRMMRGIRFVSTLGFSLETKTKQAIETYGHLLEHIAIERITVEFEKLLTGTYCVKGLKELVETKLFSHLPYLQMSEERLLKATQYNWDSFETDIEAWAFFLYCIGEEHPSVFLRQWKFSNKKIKDIVAVLLTIRKRKEKDWDTVLLYKTGIHIAEMAERVYEAMIESYDHTSVERVQTLFQALPIKSRQEMDVTGNDLLNWASKKPGPWVAEMIQKIEEAIVQGNVVNEKECIREWLQECNLL
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
Protein: RS20_WOLPP
Sequence: MANHKSAKKMMKVIAKRTLVNKMRKSKTRTAIRRLVDIIKSGDKENVVLAFRNAESNLHKCVNKGVIHRNTAARKISRLNAKVKALMTA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: RS20_RICCN
Sequence: MANHSSAKKAARQTVKRTLINKKRSSAIKTFIKKVVHEISIGNKENANIALSVAQSKIMQGVKKNIIKLNTASRKISRLSRQIKSLKVNNTL
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: YCE6_YEAST
Sequence: MVKGKTFLKRICPEETLNEETKQEVSVGFDKMRTLLRSRESGMTFSQGPKLASCQSVINASSEKTAWTQLVFRKSKMKTYTKSVHVIFIAMGEGEDESVDMNVGISY
What are the official names of this protein?
Putative uncharacterized protein YCL046W.
Protein: COBQ_LACP7
Sequence: MAKSIMIQGTMSSAGKSLLVTALCRILKQDGYKVAPFKSQNMALNSFITEDGYEMGRAQVVQAEAAGIKPSVLMNPILLKPTTDVGSQVIVNGEVRGNMTASNYFKYKKELIPEIMHSYQTLDKEYDIIVIEGAGSPAEINLKSEDIVNMGMARMANAPVLLVGDIDRGGVFAQLYGTVALLEEEERAMIKGMIINKFRGDVKILEPGLTMLSDRLSPIANIPFVGVVPYTTVDIEEEDSISERFLRKTAKKIDIAVIRLPRISNYTDFHNLERFPNVSVRYISKVSELLEPDMIILPGTKNTIDDLKFLRESGLEAAILKAESKDTLIFGICGGYQMLGEWLHDPYGVEGGGEIKGLSLLPINTVFAKEKVRKQNSGTLNKVAGMLSGLSGKTYQGYEIHMGESTWSSKVEEEKNNCFSNKDEENLEHNTITSVLISNGAHVYGTYLHGIFDEEGICKEIIGTLCKRKGIDFEEVYEFDYKQYKEEQYDKLADAVRSSLDMKKIYQIMEEGV
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: AROA_STAA2
Sequence: MVSEQIIDISGPLKGEIEVPGDKSMTHRAIMLASLAEGTSNIYKPLLGEDCRRTMDIFRLLGVDIKEDEDKLVVNSPGYKAFKTPHQVLYTGNSGTTTRLLAGLLSGLGIESVLSGDVSIGKRPMDRVLRPLKLMDANIEGIEDNYTPLIIKPSVIKGINYQMEVASAQVKSAILFASLFSNDTTVIKELDVSRNHTETMFRHFNIPIEAERLSITTTPDAIQHIKPADFHVPGDISSAAFFIVAALITPESDVTIHNVGINPTRSGIIDIVEKMGGNIQLFNQTTGAEPTASIRIQYTPMLQPITIEGELVTKAIDELPVIALLCTQAVGTSTIKDAEELKVKETNRIDTTADMLNLLGFELQPTNDGLIIHPSEFKTNATVDSLTDHRIGMMLAVASLLSSEPVKIKQFDAVNVSFPGFLPKLKLLENEG
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYLK2_MOUSE
Sequence: MTTENGAVELGSQSLSTEQTPKAAAGDGPSASEKEPSAPATEKDLSPPNAKKDPGAPDPKNNPDPPSLKKDPAKAPGPEKKGDPVPASASSQGPSGEGDGGGGPAEGSEGPPAALPLPTATAEASIQKLDPTQAPSGNQGSGEAKAGKKAAECREAGRRGSPAFLHSPSCPAIISCSEKTLAVKPLSETTDLVFTGVSVTPDPQDPGPVKAGGTNALAEKKKEEAEKASGQAGQAKVQGDTPQRIGFQAVPSERVEVGQALCLTAREEDCFQILDDCPPPPAPFPHRIVELRTGNVNSEFSMNSKEALGGGKFGAVCTCTERATGLKLAAKVIKKQTPKDKEMVLLEIEVMNQLNHRNLIQLYAAIETSHEIILFMEYIEGGELFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIIDFGLARRYNPNEKLKVNFGTPEFLSPEVVNYDQISDKTDMWSLGVITYMLLSGLSPFLGDDDTETLNNVLSANWYFDEETFEAVSDEAKDFVSNLLTKDQSARMSAEQCLAHPWLNNLAEKAKRCNRRLKSQILLKKYLMKRRWKKNFIAVSAANRFKKISSSGALMALGV
What is the function of this protein?
Implicated in the level of global muscle contraction and cardiac function.  Phosphorylates a specific serine in the N-terminus of a myosin light chain (By similarity).
What are the official names of this protein?
Myosin light chain kinase 2, skeletal/cardiac muscle, MLCK2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Colocalizes with phosphorylated myosin light chain (RLCP) at filaments of the myofibrils.
Protein: CST11_HUMAN
Sequence: MMAEPWQALQLLLAILLTLMALPYQARKKTFLSVHEVMAVENYAKDSLQWITDQYNKESDDKYHFRIFRVLKVQRQVTDHLEYHLNVEMQWTTCQKPETTNCVPQERELHKQVNCFFSVFAVPWFEQYKILNKSCSSD
What is the function of this protein?
Has antibacterial activity against the Gram-negative bacteria E. coli.  May play a role in sperm maturation and fertilization.
What are the official names of this protein?
Cystatin-11.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
What are the subcellular locations of this protein?
Secreted. Note=Probably secreted into the epididymis lumen, where it localizes to the outer surface of sperm. Specifically localizes to the postacrosomal and tail regions of sperm.
Protein: KDSR_HUMAN
Sequence: MLLLAAAFLVAFVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEMHSINDKQVVLCISVDVSQDYNQVENVIKQAQEKLGPVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGRIVFVSSQAGQLGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYPPDTDTPGFAEENRTKPLETRLISETTSVCKPEQVAKQIVKDAIQGNFNSSLGSDGYMLSALTCGMAPVTSITEGLQQVVTMGLFRTIALFYLGSFDSIVRRCMMQREKSENADKTA
What is the function of this protein?
Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).
What are the official names of this protein?
3-ketodihydrosphingosine reductase, KDS reductase, 3-dehydrosphinganine reductase, Follicular variant translocation protein 1, FVT-1, Short chain dehydrogenase/reductase family 35C member 1.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: METK_PARPJ
Sequence: MANDYLFTSESVSEGHPDKVADQISDAILDAILAQDKYSRVAAETLCNTGLVVLAGEITTTANVDYIQVARNTIKRIGYDNTDYGIDYRGCAVLVAYDKQSPDIAQGVDRAHDNNLDQGAGDQGLMFGYACEETPELMPLPIHLSHRLVERQANLRRDGRLPWLRPDAKSQVTVRYVDGKPHAIDTVVLSTQHSPDIDLGTLREAVIEEVIKPTLPAELIKGDIKFLVNPTGRFVIGGPQGDCGLTGRKIIVDTYGGAAPHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLASRCLIQVSYAIGVAQPTSVMVNTFGTGRVSDATITRLVQEHFDLRPKGIIQMLDLLRPIYEKSAAYGHFGREEPEFTWESTDKALALAEAAGTEPVAALAE
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NFIL3_CHICK
Sequence: MQLRKMQTLKKEHGSVDTSSNVDKIMVLKSTLAEVSEELSTNEDILLTEASSGKSKSSACRRKREFIPDEKKDAMYWEKRRKNNEAAKRSREKRRLNDLVLENKLIALGEENATLKAELLSLKLKFGLISSASYAQEIQKLSSSTTVYFQDYQSSKPNINSFVDEHEPSVVGSSCISVIKHSPQSSMSDMSEMPSVEHTQGSRIQSNCRSPENKFQIIKQEPIELEREPRDDRGSYKASIYPNYMGTTFNMYSHSPPLLQVNRSSSNSPRTSETDDGVVGKSSDGEDEQQVPKGPIHSPVEHKNVHATVKVPEVNSSALPHKLRIKAKAMQVKVEAMDNDYDATQKLSSPIDMSSKRHFELEKHGAQNLVHSSHTPFSVQVTNIQDWSLKPELWHQKELNVKIQNGCKTGVVEIKDNVYNVSESENLYLKQGIANLSAEVASLKRLITTQQISASDSG
What is the function of this protein?
Acts as a transcriptional regulator (By similarity).  Represses PER2 transcription through a recognition sequence in the promoter (PubMed:11427718, PubMed:15182670).  Component of the circadian clock that may contribute to the rhythmic expression of PER2 gene in a light-dependent and time-of-day-dependent manner (PubMed:11427718, PubMed:15182670).
What are the official names of this protein?
Nuclear factor interleukin-3-regulated protein, E4 promoter-binding protein 4, cE4BP4 protein, bZIP protein E4BP4.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. NFIL3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SLP1_DROME
Sequence: MVKSEMEFKSNFSIDAILAKKPINTATQPIKTEPVHHHHQYVHPYSNSDGELSASEDFDSPSRTSTPMSSAAESLSSQNNDKLDVEFDDELEDQLDEDQESEDGNPSKKQKMTAGSDTKKPPYSYNALIMMAIQDSPEQRLTLNGIYQYLINRFPYFKANKRGWQNSIRHNLSLNKCFTKIPRSYDDPGKGNYWILDPSAEEVFIGETTGKLRRKNPGASRTRLAAYRQAIFSPMMAASPYGAPAPSYGYPAVPFAAAAAAALYQRMNPAAYQAAYQQMQYQQAPQAHHHQAPHPAQMQGYPPQLNAELFQRMQFFGKFPSS
What is the function of this protein?
Transcription factor involved in segmentation.  Required for the formation of the mandibular lobe.  Different levels of slp activity seem to be required in different segments.
What are the official names of this protein?
Fork head domain transcription factor slp1, Sloppy paired locus protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: COE2_HUMAN
Sequence: MFGIQDTLGRGPTLKEKSLGAEMDSVRSWVRNVGVVDANVAAQSGVALSRAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTAFVDFVENDKEQGNEKTNNGTHYKLQLLYSNGVRTEQDLYVRLIDSVTKQPIAYEGQNKNPEMCRVLLTHEVMCSRCCEKKSCGNRNETPSDPVIIDRFFLKFFLKCNQNCLKTAGNPRDMRRFQVVLSTTVNVDGHVLAVSDNMFVHNNSKHGRRARRLDPSEATPCIKAISPSEGWTTGGAMVIIIGDNFFDGLQVVFGTMLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGAPGRFIYTALNEPTIDYGFQRLQKVIPRHPGDPERLAKEMLLKRAADLVEALYGTPHNNQDIILKRAADIAEALYSVPRNPSQLPALSSSPAHSGMMGINSYGSQLGVSISESTQGNNQGYIRNTSSISPRGYSSSSTPQQSNYSTSSNSMNGYSNVPMANLGVPGSPGFLNGSPTGSPYGIMSSSPTVGSSSTSSILPFSSSVFPAVKQKSAFAPVIRPQGSPSPACSSGNGNGFRAMTGLVVPPM
What is the function of this protein?
Transcription factor that, in osteoblasts, activates the decoy receptor for RANKL, TNFRSF11B, which in turn regulates osteoclast differentiation.  Acts in synergy with the Wnt-responsive LEF1/CTNNB1 pathway.  Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3' (By similarity).
What are the official names of this protein?
Transcription factor COE2, Early B-cell factor 2, EBF-2.
What is the protein family that this protein belongs to?
Belongs to the COE family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DXR_ERWT9
Sequence: MKQLTILGSTGSIGTSTLAVVRANPQLFAVKALVAGRNVELMTGQCLEFRPAYAAMSDKRAAEELRLRLKDLNVATEVLSGEQAACDLAALDDVDQVMAAIVGAAGLLPTLAAIRAGKKVLLANKESLVTCGRLFLEAVSASKAQLLPIDSEHNAIFQSLPASLQQQLGYASLENNGIESIILTGSGGPFRDTPLVELPHMTPDQACAHPNWSMGRKISVDSATMMNKGLEYIEARWLFNATDAQMEVILHPQSVIHSMVRYRDGSVIAQLGSPDMRTPIAHAMAWPQRVESGVQPLDFTRMSAMTFAQPDYTRYPCLKLAMDASKAGQAATTTLNAANEIAVAAFLASEIRFTDIAALNVAVLDTLSCQEPQNVDAVIAIDREARAAAQALLPRFAAKRASVI
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: CAS6L_PYRHO
Sequence: MRIEVKLLPLKDNPILPFNYNYEVYSQILEKVNSIEPTIAKLLSSPHGFWTFSRIIVRKRKILPDKGIEILSDDVSLYISSSNEDIIRAIAEAVEKSPEFKIGELSFLVGDIKAIKVKELGKENVFSTLSPIVVRTVKFEGNKLRHWDLYPHDELFMDRLRKVMILRYSEVMGETPKDRDFTIEVLKFKPTRLMVGSSYIRGSLMVFRYAGSEEIARFGYENGFGEKTGLGFGMVKLIE
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA), also called psiRNA (prokaryotic silencing) in this organism (Potential).
What are the official names of this protein?
Putative CRISPR-associated endoribonuclease-like protein Cas6nc, PhCas6nc.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
Protein: Y2038_YERPS
Sequence: MAGHSKWANTKHRKAAQDAKRGKIFTKIIRELVTAARLGGGDPGANPRLRAAIDKALSNNMTRDTLNRAIARGVGGDEDNNMETIIYEGYGPGGTAVMVECLSDNRNRTVSEVRHAFTKTGGNLGTDGSVSYLFTKKGVISYAPGLEEDTVMDAALEAGADDIVVYDDGAIDVFTAWESLGAVKDALDATGLVAEGAEVSLIPSTKAELDAETAPKLLRLIDMLEDSDDVQEVYHNGEISDEVAATL
What are the official names of this protein?
Probable transcriptional regulatory protein YPTB2038.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEA_SALDC
Sequence: MRVTDFSFELPESLIAHYPQPERSRCRLLSLEGPTGALTHGTFTDLLDKLNPGDLLVFNNTRVIPARLFGRKASGGKIEVLVERMLDDKRILAHIRASKAPKPGTELLLGDDESIHATMTARHGALFEVEFNDPRPVLDILNAIGHMPLPPYIDRPDEDADRELYQTVYSEKPGAVAAPTAGLHFDEPLLAALREKGIEMAFVTLHVGAGTFQPVRVDTIEDHIMHSEYAEVPQEVVDAVLAAKARGNRVIAVGTTSVRSLESAAQAAKNDLIEPFFGDTQIFIYPGYQYKVIDALITNFHLPESTLIMLVSAFAGYQHTMNAYKTAVEQKYRFFSYGDAMFITYNPQAISERP
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URGT1_ARATH
Sequence: MEKPESEKKSAVSDVGAWAMNVISSVGIIMANKQLMSSSGFGFGFATTLTGFHFAFTALVGMVSNATGLSASKHVPLWELLWFSIVANISIAAMNFSLMLNSVGFYQISKLSMIPVVCVLEWILHSKHYCKEVKASVMVVVIGVGICTVTDVKVNAKGFICACTAVFSTSLQQISIGSLQKKYSVGSFELLSKTAPIQAISLLICGPFVDYLLSGKFISTYQMTYGAIFCILLSCALAVFCNISQYLCIGRFSATSFQVLGHMKTVCVLTLGWLLFDSEMTFKNIAGMAIAIVGMVIYSWAVDIEKQRNAKSTPHGKHSMTEDEIKLLKEGVEHIDLKDVELGDTKP
What is the function of this protein?
Nucleotide-sugar transporter that transports UDP-rhamnose or UDP-galactose and UMP in a strict counter-exchange mode.
What are the official names of this protein?
UDP-rhamnose/UDP-galactose transporter 1, UDP-Rha/UDP-Gal transporter 1, UDP-galactose transporter 2, At-UDP-GalT2.
What is the protein family that this protein belongs to?
Belongs to the TPT transporter family. TPT (TC 2.A.7.9) subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: RUVC_AZOSB
Sequence: MSSAGRIVATRILGLDPGLRITGFGVIDTLGSQLRYVASGCIKTRDGELPGRLKTLLDGVREVIATYQPDAVAVEKVFVNVNPQSTLLLGQARGAVICGAVSCDLPVAEYTALQVKQSVVGYGKAAKEQVQHMVQRLLALDASPGPDAADALACAICHAHGGQGLGGQAGIGGRRRAGRILSL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.