PharMolix/UniProtQA huggingface dataset:
Protein: GA6_GIBF5
Sequence: MPGKIENGTPKDLKTGNDFVSAAKSLLDRAFKSHHSYYGLCSTSCQVYDTAWVAMIPKTRDNVKQWLFPECFHYLLKTQAADGSWGSLPTTQTAGILDTASAVLALLCHAQEPLQILDVSPDEMGLRIEHGVTSLKRQLAVWNDVEDTNHIGVEFIIPALLSMLEKELDVPSFEFPCRSILERMHGEKLGHFDLEQVYGKPSSLLHSLEAFLGKLDFDRLSHHLYHGSMMASPSSTAAYLIGATKWDDEAEDYLRHVMRNGAGHGNGGISGTFPTTHFECSWIIATLLKGGFTLKQIDGDGLRGLSTILLEALRDENGVIGFAPRTADVDDTAKALLALSLVNQPVSPDIMIKVFEGKDHFTTFGSERDPSLTSNLHVLLSLLKQSNLSQYHPQILKTTLFTCRWWWGSDHCVKDKWNLSHLYPTMLLVEAFTEVLHLIDGGELSSLFDESFKCKIGLSIFQAVLRIILTQDNDGSWRGYREQTCYAILALVQARHVCFFTHMVDRLQSCVDRGFSWLKSCSFHSQDLTWTSKTAYEVGFVAEAYKLAALQSASLEVPAATIGHSVTSAVPSSDLEKYMRLVRKTALFSPLDEWGLMASIIESSFFVPLLQAQRVEIYPRDNIKVDEDKYLSIIPFTWVGCNNRSRTFASNRWLYDMMYLSLLGYQTDEYMEAVAGPVFGDVSLLHQTIDKVIDNTMGNLARANGTVHSGNGHQHESPNIGQVEDTLTRFTNSVLNHKDVLNSSSSDQDTLRREFRTFMHAHITQIEDNSRFSKQASSDAFSSPEQSYFQWVNSTGGSHVACAYSFAFSNCLMSANLLQGKDAFPSGTQKYLISSVMRHATNMCRMYNDFGSIARDNAERNVNSIHFPEFTLCNGTSQNLDERKERLLKIATYEQGYLDRALEALERQSRDDAGDRAGSKDMRKLKIVKLFCDVTDLYDQLYVIKDLSSSMK
What is the function of this protein?
Bifunctional ent-kaurene synthase; part of the gene cluster that mediates the biosynthesis of gibberellins (GAs), diterpenoids that may provide a selective advantage during infection of the preferred host plant, rice (PubMed:23825955, PubMed:9917370, PubMed:10347043, PubMed:12750377, PubMed:15925394).  Gibberellins (GAs) are diterpenoids and are synthesized via the mevalonate pathway (PubMed:12750377).  Biosynthesis of the major metabolite GA3 (gibberellic acid) from geranylgeranyl diphosphate (GGPP) requires 13 steps (PubMed:12750377).  The GGPP produced by the geranylgeranyl diphosphate synthase GGS2 is converted to ent-kaurene via ent-copalyldiphosphate in a two-step cyclization reaction performed by the bifunctional ent-copalyl diphosphate synthase/ent-kaurene synthase enzyme (CPS/KS) (PubMed:9745028, PubMed:10803977, PubMed:12750377).  Ent-Kaurene is metabolized to GAs by a series of oxidation reactions catalyzed by cytochrome P450 monooxygenases (PubMed:9917370, PubMed:12750377).  Cytochrome P450 monooxygenase P450-4 is an ent-kaurene oxidase that catalyzes the three oxidation steps between ent-kaurene and ent-kaurenoic acid (PubMed:11472927).  The highly multifunctional cytochrome P450 monooxygenase P450-1 then catalyzes four steps involving oxidation at two carbon atoms, in the main pathway from ent-kaurenoic acid to GA14 via GA12-aldehyde as well as producing kaurenolides and fujenoic acids as by-products (PubMed:11320210).  The cytochrome P450 monooxygenase P450-2 then converts GA14 to GA4 by removal of C-20 (PubMed:11943776).  GA4 is further converted to GA7 by the GA4 desaturase DES via 1,2-desaturation before cytochrome P450 monooxygenase P450-3, a 13-hydroxylase, hydroxylates GA7 to GA3, the final product of the GA-biosynthetic pathway (PubMed:12750377).
What are the official names of this protein?
Bifunctional ent-kaurene synthase, CPS/KS, Ent-copalyl diphosphate synthase, Ent-kaur-16-ene synthase, Gibberellin cluster-kaurene synthase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: HSLU_METC4
Sequence: MTTFSPREIVSELDRFIVGQKDAKRAVAIALRNRWRRQQLKGPLRDEVAPKNILMIGPTGCGKTEIARRLARLAGAPFLKIEATKFTEVGYVGRDVEQIVRDLVEVGIGLTREEKRKAVKAKAEAAAESRILDALVGPTASQATRESFRKKLRASELDDKEVEIELAPSGSQGMPMFEIPGMPGASMGAINISDMLGKALGGQRGKPRRITVAEAYAPLIAEESDKLVDDDALTREAIREVEDNGIVFLDEIDKICAREGRSGADVSREGVQRDLLPLIEGTTVATKHGPVKTDHILFIASGAFHVSKPSDLLPELQGRLPIRVELQPLTVEDFKQILTATEASLIKQTVALMETEGVTLDFTEDAIDALARVAVEVNGSVENIGARRLQTVLERVIDEISFTATDRSGETVPIDAAYVRDRVEDLAANADLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOF_SYNP2
Sequence: MANSDPIYGWLETALATIKKANWYRQPKTITSQSGATVTLNGQSVVNFASNDYLGLAGDRRLIDAAIAATEALGTGSTGSRLTSGHRQLHQDLEQAIANLKQTEDALVFSSGYLANFGTISAITNKKDLILGDQYNHSSLKNGAKLSGATVLEYDHNDLDALRQLLETHRQNYRRCLITTDSVFSMDGDLCLLPELLAIAKEFSTMLLVDEAHGTGVLGQKGAGVVEHFHCTQQPLIQVGTLSKALGSLGGYVAGSKALIDFLRNRASTWIYTTGLSPADTAAALAAIHILQEEPQRRQQLWENIRQLKSALGNHELVPSESAVLCFGLANPQQALAMGDRLLATGFFAPAIRPPTVPTSRIRVSVMATHSPQQIQGFIEIFQRCFAEFSGSSNL
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
Putative 8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: ZRG8_ASHGO
Sequence: MRTFIKSHRRSSSLEACPPKTTPKRNSTGSPTELQPPVFPPSAPRQSSSFESLQKLTSGKLFSTKLFKKSGAQKLPATPDLPAFPRGYDSRSPSCEWRALGTEVALEDIPAIKGTRTHEWGENSDVSNSVIVLNRNSISSDGSYVETRDEQSPWRLARRSLDSATQTLSSTEEYSGPEIRIRSSTPHKLREASDSFLKKRWNRQARIHSKADIAKLEGSFPMPVEAISPPFARRRSSERSQCLGASGTMEQQLNPVNPEKCSLYAACSERSQSLTKATHALVATASTEVGLQNNLNSASVELRDDLENERESLSEEDSGSSFSDDSSKFSFEVGGGINGRTSSVKYYSKPDPPMRNYIDDLFEDEDFDEDMNCYDDDQEYEEDTEHLFGASHVQLEHGYSMMHEVTDSDSEQETKSNISSVLSKGQNAIFPSSDGRFVLNSGDSNGGSNQENIGVKMLEKSISNIGLEDVEDVEDDSDGIIPTDTQEDIDSPVHSQPSHANFSHIKKYSDIFGISDSDEDTANNSSSQYPFEEGYYSSDEEPTLRAEPAANTEDGFTDALKASFKQDESSHSSTDSIDKTPTFALDTDGEYFPPTLTLNKKSEVDDLDVSEEAAPESISLSTSDLEQPADAKQDRANIISSSIMDYAIHEVATTESVESDENQTTCVPQTTRVPSKVTKYADLFNLSDENDEDGSDGEFLDDMGFNELESTPVESKKPNIPPRRLGNEYFGNFHSPVASSHNAPAVPRQHSPLSAKVILPATENTSIKSQYAVPRMGQSPLPPPARSQTLKFHDLHSSLDGEIRGTMSNLFFIDESEEDQYYQVQSKVDDDYLDEINNVPEDFNFSDNDSDTCSGKSPMFPTGLRNSFRKTRSFSEKPTGLAKEPTPTRYKLDIKNKTVTFFKNGLSRPLSEGSLHGQSIPSRAHVPPLSLRKAMSEGSLEQSAHSPLGYGSLAFGLNSLKSPEMSRTDAYGLSPIQEAISSGDASPKLVN
What is the function of this protein?
Involved in maintenance of polarized growth and daughter-cell-specific transcription.
What are the official names of this protein?
Zinc-regulated protein 8.
What is the protein family that this protein belongs to?
Belongs to the ZRG8 family.
What are the subcellular locations of this protein?
Cytoplasm. Bud. Bud neck. Bud tip.
Protein: NUOK1_RHIME
Sequence: MEIGISHYLTVSAILFTLGVFGIFLNRKNVIIILMSVELILLAVNINMVAFSAFLNDITGQVFALFILTVAAAEAAIGLAILVVFYRNRGSIAVEDVNMMKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K 1, NADH dehydrogenase I subunit K 1, NDH-1 subunit K 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPD_CHLAD
Sequence: MATTIDARALAAPLVEALLSTAAEQIRAAAPRIAGLPASDAAAVLPADLLPQVRNFLLTMVKEGLSGELNAVAEALQTYLETGRRVIDASVTSAIELSSEQQERITSELRRRYGDVHVTYHVDPTLIGGLIIRVGDQVLDNSLRARLSAVQRALQAS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RHA1_ASPAC
Sequence: MKTAALAPLFFLPSALATTVYLAGDSTMAKNGGGSGTNGWGEYLASYLSATVVNDAVAGRSARSYTREGRFENIADVVTAGDYVIVEFGHNDGGSLSTDNGRTDCSGTGAEVCYSVYDGVNETILTFPAYLENAAKLFTAKGAKVILSSQTPNNPWETGTFVNSPTRFVEYAELAAEVAGVEYVDHWSYVDSIYETLGNATVNSYFPIDHTHTSPAGAEVVAEAFLKAVVCTGTSLKSVLTTTSFEGTCL
What is the function of this protein?
Plays a key role in the degradation of rhamnogalacturonan in the cell wall.  Acts in synergy together with rhamnogalacturonase A (RGase A) and rhamnogalacturonase B (RGase B).
What are the official names of this protein?
Rhamnogalacturonan acetylesterase, RGAE.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family.
Protein: ECTC_PHEZH
Sequence: MIVRDLSQAEKTDRRVVSKGWESTRLLLKDDAMGFSFHITTIYEGAELPMHYKNHLEAVYCISGEGSIEDLATGQVHEIRPGVLYALDKHDRHVLRGRTQMVMACAFNPPVTGREVHDETGAYPLEAEMA
What is the function of this protein?
Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.
What are the official names of this protein?
L-ectoine synthase, N-acetyldiaminobutyrate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the ectoine synthase family.
Protein: L_EBORR
Sequence: MATQHTQYPDARLSSPIVLDQCDLVTRACGLYSSYSLNPQLRQCKLPKHIYRLKFDTIVSKFLSDTPVATLPIDYLVPILLRSLTGHGDRPLTPTCNQFLDEIINYTLHDAAFLDYYLKATGAQDHLTNIATREKLKNEILNNDYVHQLFFWHDLSILARRGRLNRGNNRSTWFVHDEFIDILGYGDYIFWKIPLSLLPVTIDGVPHAATDWYQPTLFKESILGHSQILSVSTAEILIMCKDIITCRFNTSLIASIAKLEDVDVSDYPDPSDILKIYNAGDYVISILGSEGYKIIKYLEPLCLAKIQLCSKFTERKGRFLTQMHLSVINDLRELISNRRLKDYQQEKIRDFHKILLQLQLSPQQFCELFSVQKHWGHPILHSEKAIQKVKRHATILKALRPNVIFETYCVFKYNIAKHYFDSQGTWYSVISDRNLTPGLNSFIKRNHFPSLPMIKDLLWEFYHLNHPPLFSTKVISDLSIFIKDRATAVEQTCWDAVFEPNVLGYNPPNKFSTKRVPEQFLEQEDFSIESVLNYAQELHYLLPQNRNFSFSLKEKELNIGRTFGKLPYLTRNVQTLCEALLADGLAKAFPSNMMVVTEREQKESLLHQASWHHTSDDFGENATVRGSSFVTDLEKYNLAFRYEFTAPFIEYCNHCYGVRNVFNWMHYLIPQCYMHVSDYYNPPHNVNLSNREYPPEGPSSYRGHLGGIEGLQQKLWTSISCAQISLVEIKTGFKLRSAVMGDNQCITVLSVFPLKTDPEEQEQSAEDNAARVAASLAKVTSACGIFLKPDETFVHSGFIYFGKKQYLNGVQLPQSLKTAARMAPLSDAIFDDLQGTLASIGTAFERAISETRHILPCRIVAAFHTYFAVRILQYHHLGFNKGIDLGQLSLSKPLDYGTITLTLAVPQVLGGLSFLNPEKCFYRNFGDPVTSGLFQLRVYLEMVNMKDLFCPLISKNPGNCSAIDFVLNPSGLNVPGSQDLTSFLRQIVRRSITLTARNKLINTLFHASADLEDEMVCKWLLSSNPVMSRFAADIFSRTPSGKRLQILGYLEGTRTLLASKIINNNSETPVLDKLRKITLQRWNLWFSYLDHCDQLLADALQKISCTVDLAQILREYTWSHILEGRSLIGATLPCMVEQFKVKWLGQYEPCPECLNKKGSNAYVSVAVKDQVVSAWPNTSRISWTIGSGVPYIGSRTEDKIGQPAIKPRCPSSALKEAIELASRLTWVTQGGSNSEQLIRPFLEARVNLSVSEVLQMTPSHYSGNIVHRYNDQYSPHSFMANRMSNTATRLIVSTNTLGEFSGGGQAARDSNIIFQNVINLAVALYDIRFRNTNTSDIRHNRAHLHLTECCTKEVPAQYLTYTSALNLDLSRYRDNELIYDSNPLKGGLNCNLTIDSPLVKGPRLNMIEDDLLRFPHLSGWELAKTVVQSIISDNSNSSTDPISSGETRSFTTHFLTYPQIGLLYSFGAVLCFYLGNTILWTKKLDYEQFLYYLHNQLHNLPHRALRVFKPTFKHASVMSRLMEIDSNFSIYIGGTSGDRGLSDAARLFLRTAIASFLQFLKSWIIDRQKTIPLWIVYPLEGQQPESINEFLHKILGLLKQGPKSIPKEVSIQNDGHLDLAENNYVYNSKSTASNFFHASLAYWRSRKSRKTQDHNDFSRGDGTLTEPVRKFSSNHQSDEKYYNVTCGKSPKPQERKDFSQYRLSNNGQTMSNHRKKGKFHKWNPCKMLMESQRGTVLTEGDYFQNNTPPTDDVSSPHRLILPFFKLGNHNHAHDQDAQELMNQNIKQYLHQLRSMLDTTIYCRFTGIVSSMHYKLDEVLLEYNSFDSAITLAEGEGSGALLLLQKYSTRLLFLNTLATEHSIESEVVSGFSTPRMLLPIMQKVHEGQVTVILNNSASQITDITSSMWLSNQKYNLPCQVEIIMMDAETTENLNRSQLYRAVYNLILDHIDPQYLKVVVLKVFLSDIEGILWINDYLAPLFGAGYLIKPITSSARSSEWYLCLSNLISTNRRSAHQTHKACLGVIRDALQAQVQRGVYWLSHIAQYATKNLHCEYIGLGFPSLEKVLYHRYNLVDTGLGPLSSVIRHLTNLQAEIRDLVLDYNLMRESRTQTYHFIKTAKGRITKLVNDFLKFSLIVQALKNNSSWYTELKKLPEVINVCNRFYHTHNCECQEKFFVQTLYLQRLRDAEIKLIERLTGLMRFYPEGLIYSNHT
What is the function of this protein?
RNA-directed RNA polymerase that catalyzes the replication of viral genomic RNA.  The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N).  The replicase mode is dependent on intracellular N protein concentration.  In this mode, the polymerase replicates the whole viral genome without recognizing transcriptional signals, and the replicated genome is not caped or polyadenylated.
What are the official names of this protein?
RNA-directed RNA polymerase L, Protein L, Large structural protein, Replicase, Transcriptase.
What are the subcellular locations of this protein?
Host cytoplasm. Virion.
Protein: SIGA_NOSS1
Sequence: MNQANNVLDSIYQPDLEIMNQPEIELDDLLIEEDEDLLLADDGDIDEFLEPQTDEDDAKSGKAAKSRRRTQSKKKHYTEDSIRLYLQEIGRIRLLRADEEIELARKIADLLELERVRERLSEKLERDPRDSEWAEAVQLPLPAFRYRLHIGRRAKDKMVQSNLRLVVSIAKKYMNRGLSFQDLIQEGSLGLIRAAEKFDHEKGYKFSTYATWWIRQAITRAIADQSRTIRLPVHLYETISRIKKTTKLLSQEMGRKPTEEEIATRMEMTIEKLRFIAKSAQLPISLETPIGKEEDSRLGDFIESDGETPEDQVSKNLLREDLEKVLDSLSPRERDVLRLRYGLDDGRMKTLEEIGQIFNVTRERIRQIEAKALRKLRHPNRNSVLKEYIR
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  This sigma factor is the primary sigma factor during exponential growth.
What are the official names of this protein?
RNA polymerase sigma factor SigA, Sigma-A.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSL_ALIF1
Sequence: MSKDTASQPSLTKLIGLDIFGVGRLHAILLICIFLSAIGVVLATHNTRQMTVQRENLLLEKDILDGEWRNLILEESALAEHSRVQARSVRELDMERPAPDKEVIIKLR
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsL.
What is the protein family that this protein belongs to?
Belongs to the FtsL family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum where it forms a ring structure.
Protein: KPYK2_ECOLI
Sequence: MSRRLRRTKIVTTLGPATDRDNNLEKVIAAGANVVRMNFSHGSPEDHKMRADKVREIAAKLGRHVAILGDLQGPKIRVSTFKEGKVFLNIGDKFLLDANLGKGEGDKEKVGIDYKGLPADVVPGDILLLDDGRVQLKVLEVQGMKVFTEVTVGGPLSNNKGINKLGGGLSAEALTEKDKADIKTAALIGVDYLAVSFPRCGEDLNYARRLARDAGCDAKIVAKVERAEAVCSQDAMDDIILASDVVMVARGDLGVEIGDPELVGIQKALIRRARQLNRAVITATQMMESMITNPMPTRAEVMDVANAVLDGTDAVMLSAETAAGQYPSETVAAMARVCLGAEKIPSINVSKHRLDVQFDNVEEAIAMSAMYAANHLKGVTAIITMTESGRTALMTSRISSGLPIFAMSRHERTLNLTALYRGVTPVHFDSANDGVAAASEAVNLLRDKGYLMSGDLVIVTQGDVMSTVGSTNTTRILTVE
What is the function of this protein?
Catalyzes the formation of pyruvate in the last step of glycolysis, it is irreversible under physiological conditions.  The reaction is critical for the control of metabolic flux in the second part of glycolysis.
What are the official names of this protein?
Pyruvate kinase II, PK-2.
What is the protein family that this protein belongs to?
Belongs to the pyruvate kinase family.
Protein: Y550_PSEA6
Sequence: MGRKFEVRKVAMAKTAGAKTKVYSKYGKEIYMVAKNGGTDPQANLSLRRLIDKAKKDQVPSHVIDKAIDKAAGGAGEDFTPARYEGFGPGGCMVIVDCLTDNNNRTITDVRNCFTKTNSKIGVTGTVSHMFDHQAVFSFPGDDEDAVLEVLMEADVDVTEVECEEGVITVFAPHTEYFKTRTALTDNNPELEFDADEITFVPQTETVVTGEDVATFDKFMDMLEDCDDVQDVYHNAVVEREGE
What are the official names of this protein?
Probable transcriptional regulatory protein Patl_0550.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_RHOOB
Sequence: MSPELGGGYDGESPVSADLVAGDGDIEASLRPKNLHDFIGQPRVREQLQLVLTGAKMRGGTPDHILLSGPPGLGKTSMAMIIAAELGSSLRLTSGPALERAGDLAAMLSNLVEGDVLFIDEIHRIARPAEEMLYLAMEDFRVDVVVGKGPGATSIPLEVAPFTLVGATTRSGALTGPLRDRFGFTAHMDFYEPAELKQILMRSAGILGVQLGEEAGAEIASRSRGTPRIANRLLRRVRDYAEVRADGVVTREIAHAALAVYDVDQLGLDRLDRSVLSALVRSFGGGPVGVSTLAVAVGEEPATVEEVCEPFLVRAGMIARTPRGRVATAAAWTQLGLTPPPDAVTGGIDVRVNEPQASLFDPEDP
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: TEB_ARATH
Sequence: MDSDSSKSRIDQFYVSKKRKHQSPNLKSGRNEKNVKVTGERSPGDKGTLDSYLKASLDDKSTTNSGLQARQEAFTRKLDLEVSASSVGQNIHPCLPKPVSFATFKECLGQNGSQDLHKEGVAAETHATDGLLCANQKDNSELRDFATSFLSLYCSGVQSVVGSPPHQKENELKRRSSSSSLAQDIQISHKRRCESENIPSLDDLTNPLGSKPESLARNGNNRDKPVSDPTKKMPSNESVEIPMGLRKCSKAPESSAHLTEFHTPGSAIKSCPVGTPKSGCGSSMFSPGEAFWNEAIQVADGLTIPIENFGSVEAKVRDQHVTILSCSKKTDKCTEKLERSLDLDEIRVKDKDAIGFSKVVEKHGRDFNKEVYQLPVKNLELLFQDKNINGGIQERCASFDQNNITLGSSRISESAFVGNKGCENLDIANNAQADKGLIGKMYPEPEGKKVLLCEENRGVRSVSMISNMRKPVGSSESEESHTPSSSHRNYDGLSLSTWLPSEVCSVYNKKGISKLYPWQVECLQVDGVLQKRNLVYCASTSAGKSFVAEVLMLRRVIRTGKMALLVLPYVSICAEKAEHLEVLLEPLGKHVRSYYGNQGGGTLPKDTSVAVCTIEKANSLINRLLEEGRLSELGIIVIDELHMVGDQHRGYLLELMLTKLRYAAGEGSSESSSGESSGTSSGKADPAHGLQIVGMSATMPNVGAVADWLQAALYQTEFRPVPLEEYIKVGSTIYNKKMEVVRTIPKAADMGGKDPDHIVELCNEVVQEGNSVLIFCSSRKGCESTARHISKLIKNVPVNVDGENSEFMDIRSAIDALRRSPSGVDPVLEETLPSGVAYHHAGLTVEEREIVETCYRKGLVRVLTATSTLAAGVNLPARRVIFRQPMIGRDFIDGTRYKQMSGRAGRTGIDTKGDSVLICKPGELKRIMALLNETCPPLQSCLSEDKNGMTHAILEVVAGGIVQTAKDIHRYVRCTLLNSTKPFQDVVKSAQDSLRWLCHRKFLEWNEETKLYTTTPLGRGSFGSSLCPEESLIVLDDLLRAREGLVMASDLHLVYLVTPINVGVEPNWELYYERFMELSPLEQSVGNRVGVVEPFLMRMAHGATVRTLNRPQDVKKNLRGEYDSRHGSTSMKMLSDEQMLRVCKRFFVALILSKLVQEASVTEVCEAFKVARGMVQALQENAGRFSSMVSVFCERLGWHDLEGLVAKFQNRVSFGVRAEIVELTSIPYIKGSRARALYKAGLRTSQAIAEASIPEIVKALFESSAWAAEGTGQRRIHLGLAKKIKNGARKIVLEKAEEARAAAFSAFKSLGLDVNELSKPLPLAPASSLNGQETTERDISRGSVGPDGLQQSIEGHMECENFDMDNHREKPSEVLGDATLGVSSEINLTSRLPNFRPIGTAVGTNGPSAVSILSSDTFPIPVYDNREIKPKDNVEQHLTRNDHIPLSSNKDGTGEKGPVTAGNISGGFDSFLELWGSAGEFFFDLHYNKLQDLNSRISYEIHGIAICWNCSPVYYVNLNKDLPNLECVEKQKLIEDAVIGKSEVLASHNMLDVIKSRWNKISKIMGNVNTRKFTWNLKVQIQVLKSPAISIQRCTRLNLPEGIRDELVDGSWLMMPPLHTSHTIDMSIVIWILWPDEERHSNPNIDKEVKKRLSPEAAEAANRSGRWRNQIRRVAHNGCCRRVAQTRALCSALWKILVSEELLQALTTIEMPLVNVLADMELWGIGIDIEGCLRARNILRDKLRSLEKKAFELAGMTFSLHNPADIANVLFGQLKLPIPENQSKGKLHPSTDKHCLDLLRNEHPVVPIIKEHRTLAKLLNCTLGSICSLAKLRLSTQRYTLHGRWLQTSTATGRLSIEEPNLQSVEHEVEFKLDKNGRDVSSDADRYKINARDFFVPTQENWLLLTADYSQIELRLMAHFSRDSSLISKLSQPEGDVFTMIAAKWTGKAEDSVSPHDRDQTKRLIYGILYGMGANRLAEQLECTSDEAKEKIRSFKSSFPAVTSWLNETISFCQEKGYIQTLKGRRRFLSKIKFGNAKEKSKAQRQAVNSMCQGSAADIIKIAMINIYSAIAEDVDTAASSSSSETRFHMLKGRCRILLQVHDELVLEVDPSYVKLAAMLLQTSMENAVSLLVPLHVKLKVGKTWGSLEPFQTD
What is the function of this protein?
Required for regulated cell division and differentiation in meristems and embryos, thus modulating adaxial-abaxial polarity.  Regulates the progression of cell cycle and DNA replication (e. g.  G2/M progression and intrachromosomal recombination) and the expression of genes during development, especially genes nearby the Helitron transposons.
What are the official names of this protein?
Helicase and polymerase-containing protein TEBICHI.
What is the protein family that this protein belongs to?
Belongs to the helicase family.
Protein: ZSC21_PONPY
Sequence: MMTKVLGMAPVLGPRPPQEQVGPLMVKVEEKEEKGKYLPSLEMFRQRFRQFGYHDTPGPREALSQLRVLCCEWLRPEIHTKEQILELLVLEQFLTILPQELQAWVQEHCPESAEEAVTLLEDLERELDEPGHQVSTPPNEQKPVWEKISSSGTAKESPSSVQPQPLETSHKYESWGPLYIQESGEEQAFAQDPRKVRDCRLSTQHEESADEQKASEAEGLKGDIISVIIANKPEARLERQCVNLXXEKGTKPPLQESGSKKGRESVPTKPTPGERRYICAECGKAFSNSSNLTKHRRTHTGEKPYVCTKCGKAFSHSSNLTLHYRTHLVDRPYDCKCGKAFGQSSDLLKHQRMHTEEAPYQCKDCGKAFSGKGSLIRHYRIHTGEKPYQCNECGKSFSQHAGLSSHQRLHTGEKPYKCKECGKAFNHSSNFNKHHRIHTGEKPYWCHHCGKTFCSKSNLSKHQRVHTGEGEAP
What is the function of this protein?
Strong transcriptional activator (By similarity).  Plays an important role in spermatogenesis; essential for the progression of meiotic prophase I in spermatocytes (By similarity).
What are the official names of this protein?
Zinc finger and SCAN domain-containing protein 21.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SCPA_MYCGE
Sequence: MISLIFDKSNSFNPQLCVELLNHFKVVMLTKTIVVDYPSFQAWKAQLKPFKLAVFSDNLQTELTPNSKLTVFNNYQQLLVDNNDLIIFATPTLVQLFDNEIDQLIVINPTSKSKDQFNCNWNDFVLIKQTNFKNHQVGYFDKKSSYEPPFTVVTDHFFGNLTDLFSLLVDKKVSVNDVDIGLISLQYLNIIANYTNKKAIEKITDYLVITSKILAKKADNLLNDHQEESVLEYDLATNNFRDKMIANLVEHKRYCDSLGEFEKLRVNRLAYFSKANEMEQFIKTANDQLVTVEDQLPNYISVLKLFHAMNKLLEMRLSSLLTNKNITIKELSVEQVQKELVLAIKQFNYQTVSLKRVLLKLNHPISLMYFVTAFVALLVLLNNQVIGLEQKDYHSELYIFLLDENQLKTFQESPDEMVKRIQAQQQQNELIIAKNKQLRAIKNKQKRADYLKKKYGENYLDKTNLKDENNN
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity).
What are the official names of this protein?
Segregation and condensation protein A.
What is the protein family that this protein belongs to?
Belongs to the ScpA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: NUOB2_CHRVO
Sequence: MDSPSLEKDGFLLTTLDGLFGRAQSGSLWYLSFGLACCAVEMMHAAAARYDMDRFGWIPRATPRQADLMIVAGTLTNKMAPAMRKVYDQMSEPRYVLSMGSCANGGGYYHYSYAVVRGCDRIVPVDVYVPGCPPTAEALLYGLMQLQAKIRRDDTASRRELLDRSPNRQPN
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B 2, NADH dehydrogenase I subunit B 2, NDH-1 subunit B 2.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SYC_DEIRA
Sequence: MTQPTITQDTARQPNPNITLYDTMQRQKVPFVPGTPGYVGMYLCGPTVYSDAHLGHAKKEVAFDVIRRALTHFGYQVRYVSNITDVGHLLNDADEGEDKLQARARLEQLEPMEVADKYFWSFFRDMDALNVLRPSINPRATGHIQEQIKLIEELIEKGHAYESAGSVYFDVRSWPEYGKLSGRKLDDQEEGTREAVRDEKRDPRDFALWKKAEPEHLMRWDSPWSVGFPGWHIECSAMSLKYLGEGFDIHGGGLDLQFPHHEAEIAQAEAAGHHFARYWMHNNMLTIGGEKMSKSKGNFTTIQDILKKYDPMVVRFLLVSSHYRSVTEMNEEAFASAANGYRRLSETLHEIERRLKDAPAGSDTALDSKIAARVTEFEDAMRDDFNTPKAVASLFGLTGELNTALNAGPVGRDTLERARDAYRSLGGDVLGLFAETGSAASVAQDDASVIDALMDLVLKARQNYRLQKQYAEADELRETLGKAGITVEDTKDGARWKR
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.