PharMolix/UniProtQA huggingface dataset:
Protein: LPXD_RICCK
Sequence: MASSNFYKNLGPRKLTTIIDFLHDIIEHPKIYEDIVIHDIKILQEASRNDISFLSNTKYSEFLKTTNAAACIVPKNFKGEVNPNTILIHAENSYFAYGKLIDFFYAPIKSYPAKIMKSAIVAASAIIGKNCYIGHNVVIEDDVIIGDNSIIEAGSFIGRGVNLGRNARIEQHVSINYAIIGDDVVILTGAKIGQDGFGFSTEKGVHHQIFHTGIVKIGNNVKIGANTTIDRGSLQDTIIEDLCCIDNLVQIGHGVKIGKGSIIIAQVGIAGSSTIGKYCALGGQVGIAGHLNIGDQVQVAAQSGVAQNIEAGKIVGGSPAVHIMNWHRQSIIMKQLIKKRPK
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: 6PGL_ECO8A
Sequence: MKQTVYIASPESQQIHVWNLNHEGALTLTQVVDVPGQVQPMVVSPDKRYLYVGVRPEFRVLAYRIAPDDGALTFAAESALPGSPTHISTDHQGQFVFVGSYNAGNVSVTRLEDGLPVGVVDVVEGLDGCHSANISPDNRTLWVPALKQDRICLFMVSDDGHLVAQDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTLDMMPENFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLSKEGFQPTETQPRGFNVDHSGKYLIAAGQKSHHISVYEIVGEQGLLHEKGRYAVGQGPMWVVVNAH
What is the function of this protein?
Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
What are the official names of this protein?
6-phosphogluconolactonase, 6-P-gluconolactonase.
What is the protein family that this protein belongs to?
Belongs to the cycloisomerase 2 family.
Protein: CLCA_ECOSM
Sequence: MKTDTPSLETPQAARLRRRQLIRQLLERDKTPLAILFMAAVVGTLVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAPEAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGREGPTVQIGGNIGRMVLDVFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAVFIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGMQDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLVFIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQYHLEAGTFAIAGMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAILARTLAKQEAEQLARSKAASASENT
What is the function of this protein?
Proton-coupled chloride transporter.  Functions as antiport system and exchanges two chloride ions for 1 proton.  Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.
What are the official names of this protein?
H(+)/Cl(-) exchange transporter ClcA.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClcA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KCY_CUPTR
Sequence: MTIVNVITIDGPTASGKGTVAHKVADAVGFHLLDSGALYRLVALASDRAGVDLADIDSLTRIASRLDVKFGPDRVWLQGEEVSLAIRAEAIGNRASAIAVHQPVRDALTQLQRSFRKLPGLVADGRDMGTVIFPDAQLKVFLTASVEARARRRYKQLIDKGISANIEDLLRDLEARDARDRTRAAAPLRPAEDAKLLDTSDMTVDQAVAQVLEWFAAVRPDA
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCA3_MYCLE
Sequence: MASHASSRIAKVLVANRGEIAVRVIRAARDARLPSVAVYAEPDAEAPHVRLADEAFALGGHTSAESYLDFGKILDAAAKSGANAIHPGYGFLAENADFAQAVIDAGLIWIGPSPQSIRDLGDKVTARHIAARAQAPLVPGTPDPVKNADEVVAFAKEHGVPIAIKAAFGGGGKGMKVARTLEEISELYESAVREATVAFGRGECFVERYLDKPRHVEAQVIADQHGNIVVAGTRDCSLQRRFQKLVEEAPAPFLTDAQRKEIHESAKRICKEAHYYGAGTVEYLVGQDGLISFLEVNTRLQVEHPVTEETTGIDLVLQQFKIANGEKLELIKDPIPCGHAIEFRINGEDAGRNFLPSPGPVSKFHPPTGPGVRLDSGVETGSVIGGQFDSMLAKLIVHGATRQEALARARRALDEFEVEGLATVIPFHRAVVSDPALIGDNNSFSVHTRWIETEWNNTIEPFIDNQPLDEEDTRPQQTVIVEVDGRRLEVSLPADLALANPAGCNPAGVIRKKPKPRKRGGHTGAATSGDAVTAPMQGTVVKVAVAEGQTVMTGDLVVVLEAMKMENPVTAHKDGIITGLAVEAGTAITQGTVLAEIK
What is the function of this protein?
Component of a biotin-dependent acyl-CoA carboxylase complex.  This subunit catalyzes the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain, resulting in the formation of carboxyl biotin.
What are the official names of this protein?
Biotin-dependent acyl-coenzyme A carboxylase alpha3 subunit.
Protein: NUOM_RICTY
Sequence: MLELPIISITIFLPLISVLYILLFINQSKKANKLNIYVAMVAMLSSVLTFILTIYILIEFDASNHTYQFVERYTWLDKIGLEFHVGIDGIAIFFVVLTSFLTLICIIGSIFTIKKYIKEYLVCFLLMESFCIGAFTAVNLLLFYLFFEAILVPMYIIIGVWGGDNRIYAALKFFLYTFFGSVFFLLALIYIYSKIHSFDLTYILALTENIPLFAQKILWWTIFIAFAVKIPMIPFHTWLPDAHVQAPTSGSVILAGILLKLGSYGFLRVLLPLLPNVSQEFAIYVIYLSVIAIIYSSLVALAQKDIKQMIAYSSIAHMGYVTIGIFSFTETGISGAIFQMLSHGVVSSSLFLIVGTLYERLHTKEIAKYGGVASKMPVLATFFMITMLSSIGLPSTSGFIGEFLSLLGIYKVNVVAACIAALGIILGAVYMLKLYKEVMLGEITNTEIKHFKDLYRYEILSIAPLILIIIYFGLMPNSILNVFHLSVENLLIKF
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit M, NADH dehydrogenase I subunit M, NDH-1 subunit M.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SUCC_MYCMM
Sequence: MDLFEYQAKELFAKHNVPTTPGRVTDTAEGARAIATEIGHPVMVKAQVKIGGRGKAGGVKYAATPDDAYEHANNILGLDIKGHVVKKLLVAEASDIAEEYYISFLLDRANRTYLAMCSVEGGMEIEEVAATKPDRLAKVPVDAAKGVDLAFARSIAEQGHLPAEVLDAAAVTISKLWDLFVGEDATLVEVNPLVRTPDDQILALDGKVTLDANADFRHPDHVEFEDRAATDPLELKAKEHDLNYVKLDGQVGIIGNGAGLVMSTLDVVAYAGEKHGGVKPANFLDIGGGASAEVMAAGLDVVLGDSQVKSVFVNVFGGITSCDAVATGIVKALEILGAEANKPLVVRLDGNNVEEGRRILTDANHPLVTLVPTMDEAADKAAELASA
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: PYRE_ACTSZ
Sequence: MQDYKIEFIKFALSRNVLRFGEFKLKSGRVSPYFFNAGLFNTGADLARLGEFYAAAIQANRLAYDVIFGPAYKGIPIGTTVSVALFNRFGLDKPVCFNRKEAKDHGEGGNLIGSPLQGNVLLVDDVITAGTAIREAMDIIAANGATLSAVVIALNRKERGKGELSAVQEVERDYQCRVLSIIELDDLLAFLETDSEYSRYLPSMKAYREQFGVA
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: TRPA_YERPN
Sequence: MERYQQLFKQLAAKKEGAFVPFVQLGDPSPAMSLNIIDTLIAAGADALELGIPFSDPLADGPTIQNAALRAFAAGVTPGICFEILAEIRQKHPTIPIGLLMYANLVFHNGIDHFYQRCAEVGVDSVLIADVPFEESAPFRAAALRHGIAPIFICPPNADDDLLREIASHGRGYTYLLSRAGVTGAENHGQLPLNHLVDKLREYNAAPALQGFGISEPAQVKASLAAGAAGAISGSAIVKIIEKNVAQPVEMLVQLTRFVTEMKAATRS
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: RL2_MYCAP
Sequence: MAVKHYKPVTNGRRNMSSLDYSKNLSGHAPEKSLLVILKKNSGRNNQGKITVRHQGGRVKRYYRIIDFKRNKDDIPATVKSIEYDPNRSANICLLAYADGEKRYILAPEGIKVGQKVVSGNNVDILVGNSLPLSNIPEGTFVHNVEMQPGGGGIIARSAGTSAQILGKDDDGKYVVLRLKSGEMRRILARCRATIGTVGNGEHSLVLLGKAGRSRHLGVRPTVRGSVMNPIDHPHGGGVSKQPIGRKAPLTPWGKKALGVKTRKTKKSSTKLILRRRKDSK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: PG095_VAR67
Sequence: MGAAASIQTTVNTLSERISSKLEQEANASAQTKCDIEIGNFYIRQNHGCNLTVKNMCSADADAQLDAVLSAATETYSGLTPEQKAYVPAMFTAALNIQTSVNTVVRDFENYVKQTCNSSAVVDNKLKIQNVIIDECYGAPGSPTNLEFINTGSSKGNCAIKALMQLTTKATTQIAPRQVAGTGVQFYMIVIGVIILAALFMYYAKRMLFTSTNDKIKLILANKENVHWTTYMDTFFRTSPMVIATTDIQN
What is the function of this protein?
Component of the entry fusion complex (EFC), which consists of 11 proteins.  During cell infection, this complex mediates entry of the virion core into the host cytoplasm by a two-step mechanism consisting of lipid mixing of the viral and cellular membranes and subsequent pore formation.
What are the official names of this protein?
Entry-fusion complex associated protein OPG095, EFC-associated protein OPG095, Protein L1, Virion membrane protein M25.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG095 family.
Protein: PAND_BURP6
Sequence: MQRHMLKSKIHRAAVTHCELHYEGSCAIDEDLLEAANIVENERIDIWNINNGERFSTYAIKGERGSGMISLNGSAARRAQLGDLVIIAAFAMIDEQELKAGWKPDLVFVDEDNKIKGSRDHVPTQNWT
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIL_ECOL6
Sequence: MACGEFSLIARYFDRVRSSRLDVELGIGDDCALLNIPEKQTLAISTDTLVAGNHFLPDIDPADLAYKALAVNLSDLAAMGADPAWLTLALTLPDVDEAWLESFSDSLFDLLNYYDMQLIGGDTTRGPLSMTLGIHGFVPMGRALTRSGAKPGDWIYVTGTPGDSAAGLAILQNRLQVADAKDADYLIKRHLRPSPRILQGQALRDLANSAIDLSDGLISDLGHIVKASDCGARIDLALLPFSDALSRHVEPEQALRWALSGGEDYELCFTVPELNRGALDVALGHLGVPFTCIGQMTADIEGLCFIRDGEPVTLDWKGYDHFATP
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
What are the official names of this protein?
Thiamine-monophosphate kinase, TMP kinase, Thiamine-phosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-monophosphate kinase family.
Protein: CH60_STRE4
Sequence: MAKDIKFSADARESMVRGVDILADTVKVTLGPKGRNVVLEKAFGSPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREGLKNVTAGANPIGIRRGIEAATTTAVEALKAVAQPVSGKEAIAQVASVSSRSEKVGDYISEAMERVGNDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDNEKMVADLENPFILITDKKISNIQDILPLLEEVLKTSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKAPGFGDRRKAMLEDIAVLTGGTVITEDLGLELKDATMAALGQAAKVTVDKDNTVIVEGAGSSEAISNRVSLIKSQLETTTSEFDREKLQERLAKLAGGVAVIKVGAATETELKEMKLRIEDALNATRAAVEEGIVAGGGTALINVMDKVAALELDGDAATGRNIVLRALEEPVRQIAYNAGYEGSVIIDKLKNSAAGIGFNAATGEWVDMIATGIIDPVKVTRSALQNAASVAGLILTTEAVVATKPEPAAPAMPQGMDPGMMGGF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HFQ_CITK8
Sequence: MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVSHHSNNAGGGTSSNYHHGSSAQGTSAQQDSEETE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: PER5_CYCRE
Sequence: TQLEAACPNVVSCADILALAAR
What is the function of this protein?
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.  These functions might be dependent on each isozyme/isoform in each plant tissue.
What are the official names of this protein?
Peroxidase 5.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.
What are the subcellular locations of this protein?
Secreted. Secreted, cell wall.
Protein: ECFA1_CLOAB
Sequence: MYNKMVECKNVVYQYKNEDESKNTTAVNDVTLEVNEGEFLVILGRNGSGKSTLAKHLNALLVPTDGKVIVEGLDTSNEEDVWTIRSKTGMVFQNPDNQIVATIVEEDVAFGPENLGVKPSEIRERVDNALKSVGMYEYRKHEPHLLSGGQKQRVAIAGVLAMHPKCIVFDESTAMLDPKGREEVVNTIMDLNKNSHITIILITHYMEEAINADRIVVMDKGKVIKSGVPREVFKDVKTMKEIGLDVPQMTELAYELKKEGINVKDDILTIDEMVNELCRLK
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA1, ECF transporter A component EcfA1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: DHSC_BACSU
Sequence: MSGNREFYFRRLHSLLGVIPVGIFLIQHLVVNQFAARGAEAFNSAAHFMDSLPFRYALEIFIIFLPLIYHAVYGVYIAFTAKNNAGQYSYMRNWLFVLQRVTGIITLIFVSWHVWETRIAAQMGAEVNFDMMANILSSPAMLGFYIVGVLSTIFHFSNGLWSFAVTWGITVTPRSQRISTYVTLIIFVALSYVGLKAIFAFV
What is the function of this protein?
Di-heme cytochrome of the succinate dehydrogenase complex.
What are the official names of this protein?
Succinate dehydrogenase cytochrome b558 subunit, Cytochrome b-558.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b558 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y2009_RALSO
Sequence: MIIVLSPAKSLDYDTPPRIKTHTLPDFIERSAVLIETLRKLSPAQIGTLMHISDPLAVLNANRYADWSTEFTADNSKQAVLAFDGDVYGGLDANTLSADDLQFAQQHLRILSGLYGVLRPLDRMQPYRLEMGTRLANPGGKDLYAFWGDDVTLALNALLQADDDPVLVNLASEEYFKVVRPKVLKARIVTPVFEDWKGGRYKIISFYAKRARGLMARYAIEHRIADPRKLKHFDAEGYAFAAEASDDERWVFRRKAA
What are the official names of this protein?
UPF0246 protein RSc2009.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: BETB_PSESM
Sequence: MARFELQKLYIDGGYVDASNTETFDSINPANGEVLAKIQRASKEDVERAVVAAEKGQKIWAAMTAVERSRILRRAVDILRERNDELAALETLDTGKAISETRYVDIVTGADVLEYYAGLVPAIEGEQIPLRDSSFVYTRREPLGVVAGIGAWNYPIQIALWKSAPALAAGNAMIFKPSEVTSLTTLKLAEIYTEAGVPNGVFNVLTGSGREVGTWITEHPRIEKVSFTGGTDTGKKVMASASSSSLKEVTMELGGKSPLIVFDDADLDRAADIAMMANFYSSGQVCTNGTRVFVPNALKGEFEAKILERVKRIRPGNPEDENINFGPLVSFEHMESVLGYIAKGKEQGARLLCGGDRLTGGVFDKGAFVAATVFTDCTDEMTIVREEIFGPVMSILGYDTEDEVVRRANDTDFGLAAGIVTRDLNRAHRVIHLLEAGICWINAWGESAAQMPVGGYKQSGVGRENGISSLAQYTRIKSVQIELGDYASVF
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
What are the official names of this protein?
Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: PIPS_MYCBP
Sequence: MSKLPFLSRAAFARITTPIARGLLRVGLTPDVVTILGTTASVAGALTLFPMGKLFAGACVVWFFVLFDMLDGAMARERGGGTRFGAVLDATCDRISDGAVFCGLLWWIAFHMRDRPLVIATLICLVTSQVISYIKARAEASGLRGDGGFIERPERLIIVLTGAGVSDFPFVPWPPALSVGMWLLAVASVITCVQRLHTVWTSPGAIDRMAIPGKGDR
What is the function of this protein?
Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP.  PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid for mycobacteria required for formation of their cell wall.
What are the official names of this protein?
Phosphatidylinositol phosphate synthase, PIP synthase, CDP-diacylglycerol--D-myo-inositol-3-phosphate 3-phosphatidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GCSH_ECO81
Sequence: MSNIPAELKYSKEHEWLRKEADGTYTVGITEHAQELLGDMVFVDLPEVGATVSAGDDCAVAESVKAASDIYAPVSGEIVAVNDALSDSPELVNSEPYAGGWIFKIKASDESELESLLDATAYEALLEDE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: TXND5_DROME
Sequence: MLTRSILSVAVCGLLLSPLLPITRASQEEDTGKQDKQFTVELDPETFDTAIAGGNVFVKFFAPWCGHCKRIQPLWEQLAEIMNVDNPKVIIAKVDCTKHQGLCATHQVTGYPTLRLFKLGEEESVKFKGTRDLPAITDFINKELSAPAEADLGEVKREQVENLNIGKVVDLTEDTFAKHVSTGNHFVKFFAPWCSHCQRLAPTWEDLAKELIKEPTVTISKIDCTQFRSICQDFEVKGYPTLLWIEDGKKIEKYSGARDLSTLKTYVEKMVGVPLEKTAGEAGDEKVVIEEVAGEEDAAKKLTPQQLTGEDEFDQAIAEGVAFIKFYAPWCGHCQKLQPTWEQLATETHQAQSSVKIAKVDCTAPENKQVCIDQQVEGYPTLFLYKNGQRQNEYEGSRSLPELQAYLKKFLGHDEL
What is the function of this protein?
Possesses thioredoxin activity (By similarity).  Acts as a ligand for Drpr and is required for the phagocytosis of apoptotic cells (PubMed:19927123, PubMed:23337816).  Binds to the extracellular region of Drpr and augments Drpr tyrosine phosphorylation (PubMed:19927123, PubMed:23337816).
What are the official names of this protein?
Thioredoxin domain-containing protein 5 homolog, Protein pretaporter.
What is the protein family that this protein belongs to?
Belongs to the protein disulfide isomerase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Cell surface. Note=Relocates from the endoplasmic reticulum to the cell surface during apoptosis.
Protein: COX1_HALSA
Sequence: MATAASSITLTVLMGVLLVGVVAVLARLEDWRSYTPLSDVGGGLGERTGYTHEEKPGGIIRWFTTVDHKDIGILYGVYGTIAFAWGGVSVLLMRTELATSSETLISPSLYNGLLTSHGITMLFLFGTPMIAAFGNYFIPLLIDADDMAFPRINAIAFWLLPPGAILIWSGFLIPGIATAQTSWTMYTPLSLQMSSPAVDMMMLGLHLTGVSATMGAINFIATIFTERGEDVGWPDLDIFSWTMLTQSGLILFAFPLFGSALIMLLLDRNFGTTFFTVAGGDPIFWQHLFWFFGHPEVYVLVLPPMGIVSLILPKFSGRKLFGFKFVVYSTLAIGVLSFGVWAHHMFTTGIDPRIRSSFMAVSLAISIPSAVKVFNWITTMWNGKLRLTAPMLFCIGFVQNFIIGGVTGVFLAVIPIDLILHDTYYVVGHFHFIVYGAIGFALFAASYYWFPMVTGRMYQKRLAHAHFWTALVGSNATFLAMLWLGYGGMPRRYATYIPQFATAHRLATVGAFLIGVSTLIWLFNMATSWREGPRVDSTDPWDLEETDQFTNDWAWFRAKEETTVLPDGGDEAQSEADAVTDGGQPAADSDTES
What is the function of this protein?
Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Subunits 1-3 form the functional core of the enzyme complex.  CO I is the catalytic subunit of the enzyme.  Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
What are the official names of this protein?
Cytochrome c oxidase polypeptide 1, Cytochrome aa3 subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RISB2_BRUSU
Sequence: MNQSCPNKTSFKIAFIQARWHADIVDEARKSFVAELAAKTGGSVEVEIFDVPGAYEIPLHAKTLARTGRYAAIVGAAFVIDGGIYRHDFVATAVINGMMQVQLETEVPVLSVVLTPHHFHESKEHHDFFHAHFKVKGVEAAHAALQIVSERSRIAALV
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase 2, DMRL synthase 2, LS 2, Lumazine synthase 2.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: DMP9_ARATH
Sequence: MEKTEESVGIRVYTATPPQKPSPSPPSRSPKPVLISSLPSLPSGAAAGGGRGRKRRMVAQGVQKTVSKTSMLVNFLPTGTLLMFEMVLPSIYRDGDCNGINTLMIHLLLLLCAMSCFFFHFTDSFKASDGKIYYGFVTPRGLAVFMKPPPPEFGGGDVIAEAEIPVTDDRYKLTVNDFVHAVMSVLVFMAIAFSDRRVTGCLFPGKEKEMDQVMESFPIMVGIVCSALFLVFPTTRYGVGCMTG
What is the function of this protein?
Involved in membrane remodeling.
What are the official names of this protein?
Protein DMP9, AtDMP9, Protein DUO1-ACTIVATED UNKNOWN 2.
What is the protein family that this protein belongs to?
Belongs to the plant DMP1 protein family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Vacuole membrane; Multi- pass membrane protein.
Protein: GDF3_HUMAN
Sequence: MLRFLPDLAFSFLLILALGQAVQFQEYVFLQFLGLDKAPSPQKFQPVPYILKKIFQDREAAATTGVSRDLCYVKELGVRGNVLRFLPDQGFFLYPKKISQASSCLQKLLYFNLSAIKEREQLTLAQLGLDLGPNSYYNLGPELELALFLVQEPHVWGQTTPKPGKMFVLRSVPWPQGAVHFNLLDVAKDWNDNPRKNFGLFLEILVKEDRDSGVNFQPEDTCARLRCSLHASLLVVTLNPDQCHPSRKRRAAIPVPKLSCKNLCHRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFSLTISLNSSNYAFMQALMHAVDPEIPQAVCIPTKLSPISMLYQDNNDNVILRHYEDMVVDECGCG
What is the function of this protein?
Growth factor involved in early embryonic development and adipose-tissue homeostasis.  During embryogenesis controls formation of anterior visceral endoderm and mesoderm and the establishment of anterior-posterior identity through a receptor complex comprising the receptor ACVR1B and the coreceptor TDGF1/Cripto (By similarity).  Regulates adipose-tissue homeostasis and energy balance under nutrient overload in part by signaling through the receptor complex based on ACVR1C and TDGF1/Cripto (PubMed:21805089).
What are the official names of this protein?
Growth/differentiation factor 3, GDF-3.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted. Cytoplasm. Note=Mainly accumulated in the cytoplasm.
Protein: FLA5_ARATH
Sequence: MGLKASLSLLSLTILLVFSKVVTANNITLAFQKYSKFSTMRDLFIKTKLIAAIDKYQTITVLAVSNDAISSITNRSEVELRNILMTHVILDYYDELKLQGMREKSIMLTTLYQTTGLGEQMNGFLNVSKSKGRVYFGSEVKNSPLNAEYVSTVYHNPYNLSIIQITMPIVAPGLSLAIFPPPPPYVHVAPYPTPMDASVVPAPGPAADDNSPDSAVPKTPPAPATDTPEADSPAPAPSADNEKIEAADKAKPSSSASKAGWSFDVILLLAFLASFAGF
What is the function of this protein?
May be a cell surface adhesion protein.
What are the official names of this protein?
Fasciclin-like arabinogalactan protein 5.
What is the protein family that this protein belongs to?
Belongs to the fasciclin-like AGP family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: RECR_AROAE
Sequence: MSPSSLDELIDALRGLPGVGPKSAQRMAYHLLQRDQRGAERLARALGNALAVLRHCERCNTFTETEICQRCASPQRDASLLCVVEMPADLAVIEQTHAYNGLYYVLMGRLSPLDGIGPRELKFDKLLARVADSTVQEVILATNFTNEGEATAHIVAELLAARGIRVSRLSRGVPVGGELEHTDTGTIAQALVERRPL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.