PharMolix/UniProtQA huggingface dataset:
Protein: PSA_MYCGI
Sequence: MSFPYFISPEQAMRERSELARKGIARGRSVIALAYADGVLFVAENPSRSLQKVSELYDRVGFAAVGRFNEFNNLRSGGIRFADTQGYAYSRRDVTGRQLANVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKAPELYRITYDGSIADEPHFVVMGGTTEPIATALNESYAENASLEDAVRIAVAALGAGGNGAEPRTLGPSTLEVAILDANRPRRAFRRITGAALEALLPQADTKDDSQDSEGAAEPDA
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit alpha, 20S proteasome alpha subunit, Proteasome core protein PrcA.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENT6_ARATH
Sequence: MADIYEHQVPEKLRGKYQAMIVYCILGFGSLISWNSMLTTADYYYKVFPDYHPSRVLTLVYQPFAFGAIVILAYHESKTSTRKRNLIGYILYTISTFLLIVLDLATKGRGGFGPYTGLCAVVAAFGLADATVQGGMFGDLSLMCPELVQSYMGGMAVAGALTSALRLITKAAFEKSNNGLRKGAMMFLAISTCIELLSVMLYAYVLPKLPIVMYYRRKAASQGSKTVSADLAAAGIQNQSDLSDDDSKNQRLSKKELLFQNIDHAVNLFLIYVCTLSIFPGFLYENTGQHGLGAWYALVLVAMYNCWDLVGRYTPLVKWLNIENRKLITIAVLSRYLLIPAFYFTAKYGDQGWMIMLVSVLGLTNGHLTVCIMTIAPKGYKGPEQNALGNLLVIFLLGGIFAGVALDWLWLIGKKNAF
What is the function of this protein?
Nucleoside transporter that can mediate uptake of adenosine, uridine, guanosine or cytidine when expressed in a heterologous system (yeast).
What are the official names of this protein?
Equilibrative nucleotide transporter 6, AtENT6, Nucleoside transporter ENT6.
What is the protein family that this protein belongs to?
Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Plasma membrane.
Protein: UPPS_PYRHO
Sequence: MIYRIISHIPKIFFKPAYDLYERYLIEKVKSGVLPKHVAIIMDGNRRWARKHEKPPWYGHLFGSKKLEEILEWCHELGIRILTVYAFSTENFKRSKEEVDRLMKLFEEKFRELVTDKRVHEYGVRVNVIGRKELLPKSVRDAVEEAERATRKYNNYILNVALAYGGRSEIVDAVKDIARDVISGKLRIEEIDEELLRRYLYVPNMPDPDIVIRTGGEVRISNFLLYQIAYSELFFVDVYFPEFRKIDFLRIIREFQKRERRFGR
What is the function of this protein?
Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP).  It is probably the precursor of glycosyl carrier lipids.
What are the official names of this protein?
Tritrans,polycis-undecaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific), Undecaprenyl diphosphate synthase, UDS, Undecaprenyl pyrophosphate synthase, UPP synthase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: ANDAD_BURCE
Sequence: MENLTEDMKTWFEIYMLQNRYIGHLDNDRLERWPEMFTEDCTYEIVPKENADLGLPVGIVHCTNQRMLRDRVVSLRHANIYEEHTYRHMTSGLAIVAQRDGEIDTESNYVVVQTRSNGESNVYQAGKYYDTVVRTPDGLRYKAKRVIYDTSRVQTLLATPI
What is the function of this protein?
Oxygenase component of anthranilate dioxygenase multicomponent enzyme system which catalyzes the incorporation of both atoms of molecular oxygen into anthranilate to form catechol.  Can also act on benzoate and salicylate but not on 2-chlorobenzoate or o-toluate.
What are the official names of this protein?
Anthranilate 1,2-dioxygenase small subunit.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.
Protein: EFG_STRP4
Sequence: MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETHEGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGAVTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAHPIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAVAETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIDYLPSPLDIPAIKGINPDTDAEEIRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVLQSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEKAKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVISGMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDVWIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLYDGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTARRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQEEIIKKNKGED
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NELFB_DROME
Sequence: MIMSTPAKNNNGTGLEDVNIPGQAYLREALTSCTDPLKAIESFQLENGVLLPSLRPMLPLLDLHGVRRLDFHTSLMEELRDKLIAHINEMGQKEPRERDKKLKELLVKSFPVVRVKSLRPVVMAILRNTQHIDDKYLKILVRDRELYADTDTEVKRQIWRDNQSLFGDEVSPLLSQYIREKEHILFDHTNLNNLFFHPTPKVRRQGEVVQKLANMIGTSVKLYDMVLQFLRTLFLRTRNVHYCTLRAELLMALHDLEVQEIISIDPCHKFTWCLDACIREKNVDIKRSRELQGFLDNIKRGQEQVLGDLSMTLCDPYAINFLATSAIKILHHLINNEGMPRDNQILILLLRMLALGLSAWVMIDSQDFKEPKLDCQVVTKFLPALMSLMVDDQCRSLHAKLPPDERESALTTIEHSGPAPDAVEAYIQESSVASILAMYYTLHTARLKDRVGVLRVLAILSACKDDRAYEDPFLHSLIALLIPMSEEFATEDFCTTLFDEFIFAGLTRENVTSRHMLKLLWYVHNKLPAGRLATLMKAMQPTTAHNEHIHKLYEILQERIGTGAAETPVIEAPPMEFDSPLKSVPTPGPHYNVQ
What is the function of this protein?
Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II.
What are the official names of this protein?
Negative elongation factor B.
What is the protein family that this protein belongs to?
Belongs to the NELF-B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Associates with polytene chromosomes. Associates with the hsp70 promoter when it is inactive, but not when it is activated.
Protein: NUOH_XYLFT
Sequence: MNTWFLNVVDPLHQWFLGFGDIGVVLWTVLKILMIAIPLIVSVAFYVVWERKLIGWMHVRHGPMYVGMGLFQAFADVFKLLFKEVLYPSKAHKAIFVIAPLLTLAPSFAAWAVVPFDTKLVLSNANVGLLYLLAMTSLGVYGIILAGWASNSKYAFLGAMRSAAQVVSYEIAMGFALVGVMIAAGSLNLSQIVMAQAGSSGFFDWFLIPLFPLFIVYWVSGVAETNRSPFDVVEGESEIVAGHMVEYSGSVFALFFLAEYANMILVSFLISIFFLGGWLSPIQGWVSGQVSPLIDWVWNGGWPWLLLKVLFFASAYIWFRASFPRYRYDQIMRLGWKVFIPLTIVWIAVTALMVFSGVIQKGV
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRUD_SERP5
Sequence: MDMANLTWLHGQPQSTGVLKANPEDFVVVEDLGFEPDGEGEHVLVNIRKNGCNTQFVADYLARFAGIHARSVSYAGLKDRHAVTEQWFCLHLPGKETPDFTQFSLEGCEVLASARHLRKMRIGTLKGNAFTLVLRHISDRQDVEPRLQAIATGGVPNYFGSQRFGRGGNNLVMARRWANDEIRVKERSKRSFYLSASRSALFNLIASRRLANQQQHTVLEGDALQLSGRGSWFVAKPEELEALQQRLDAGELMITAPLPGDGEPGTAGEALSFEQQCLLEQPELMALLKRERVDPARRALLLQPKNMHWEWWDDATVELRFWLPAGSFATSVVREIMRQDSSDADISE
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: RUVB_RHIEC
Sequence: MSEPARLISPEKRGEDLDITLRPQSLDEFTGQAEARANLKVFIEAAKNRGEALDHVLFVGPPGLGKTTLAQIMAKELGVNFRSTSGPVIAKAGDLAALLTNLEERDVLFIDEIHRLNPAVEEILYPAMEDYQLDLIIGEGPAARSVKIDLSKFTLVAATTRLGLLTTPLRDRFGIPVRLTFYTVEELELIVRRGARLMNLPMTEEGAREIARRARGTPRIAGRLLRRVRDFAEVARAEAVTREIADEALTRLLVDNVGFDQLDKRYLNMIAVNFGGGPVGIETIAAGLSEPRDAIEDIIEPYMIQQGFIQRTPRGRVLTAIAWKHLGMQPPKEMEAAQFRLFQEDD
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: GYG1_CAEEL
Sequence: MSEAWITLATNDNYAQGALVLVHSLRTAGTTRKIHCLISNEVSAPVRKQLEEHFDDVSIVDVFNSNDSDNLRLIERPDLGVTFTKLHCWRLTQYTKCVFLDADTLVLRNADELFTRPDFSAASDIGWPDSFNSGVFVYVPNNETYRQLVDFAVTHGSYDGGDQGLLNDFFSNWRDLPSEHRLPFIYNMTAGAFYTYAAAYKRYGANTKIVHFIGSVKPWHGSAAVHTGEHFQQWQKIYHAHVNHTSRTNEHAAVFPSHHHTPEHRSHSADHPKIERKDSIVREIGNFVMHVVQSVNILPSYDTDANTSDSHRNNEPHKHDQQREEHHELPHNKFQTPHEESQDIVGSTDCFGSQMPKYNADSETDREVEQITNNTPCPAFVPFERREEYQAASPSTEERRAAWEAGQPDYLGRDAFVHIQEALNRALNE
What is the function of this protein?
Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for gsy-1.
What are the official names of this protein?
Glycogenin-1, GN.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 8 family. Glycogenin subfamily.
Protein: LGT_VIBPA
Sequence: MSQGYLQFPNIDPVLVSIGPVSIRWYGLMYLVGFMFALWLANRRADKPGSGWTREQVSDLLFAGFLGVVIGGRVGYVIFYNFELFLDDPLYLFKVWTGGMSFHGGLLGVITAMFWYAHKNGRTFFGVADFVAPLVPFGLGMGRMGNFMNSELWGRVTDVPWAIVFPNGGPLPRHPSQLYEMLLEGVVLFFILNWFIKKPRPLGSVSGLFLAGYGTFRFLVEFVREPDAQLGLFGGYISMGQILSMPMIVLGILMMVWAYKRGLYQDKAQVKTK
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PUR5_METM5
Sequence: MVTYKDAGVDIYKEDKVIRALASQIKFERNDAIKPADLKGHYAGAIEFGDYYLVLCTDGVGSKMVVAEMANKFDTVPIDMIAMNVNDAICIGAEPVALVDYMAVEDITEDIASQIGKGLNDGIKESNINLIGGETASLPNMIKGVDLAGTVLAVVKKDEIVSGKEVKPGDLIVGLRSSGIHSNGLSLARKVFFDIANLDVNSKLSHGKTVAEELLTPTKIYVKPVLEMIKQVNVKGLAHITGGGFRKLKRLNKEVCYKIDELPEILPIFKEIQNLGSVADEEMFKTFNMGIGFCVIVDKEDAEKIIEISNHHNIPAFVIGKIEDSVELNGETKRETVLVEYNNKKMIME
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOZ_HAMD5
Sequence: MARVTVQAAVEKVGNRFKLILVAVHRARLLQSGRENSLVPEENDKVTVIALREIEQGLITESILKENNQHEDQIQKKVQMKTISSTQDFD
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: URK_SALA4
Sequence: MTDQSHQCVIIGIAGASASGKSLIASTLYRELREQVGDEHIGVIPEDSYYKDQSHLSMEERVKTNYDHPNAMDHSLLFQHLQALKRGSAIELPVYSYVEHTRMQETVRVEPKKVIILEGILLLTDARLREEMNFSIFVDTPLDICLMRRIKRDVNERGRSMDSVMAQYQKTVRPMFLQFIEPSKQYADIIVPRGGKNRIAIDILKAKISQFFE
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ORN_PSEA6
Sequence: MAVDAQNLVWIDMEMTGLHPEVDVVLEIATIVTDANLNILAEGPVLAIHQSDDVLNNMNQWCIDTHGKSGLTERSRKSTVDEQTAVAETIRFLEKYVPKGASPLCGNTIGQDRRFMVKYMPELEDYFHYRNIDVSTLKELVKRWKPEVLEGFSKKGVHLALDDIRESIAELVFYRQHIFNI
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_LEGPL
Sequence: MSDLLGILKQQGQSEEFDAIKIALASPELIRSWSYGEVKKPETINYRTFKPERDGLFCAKTFGPVKDYECLCGKYKRLKHRGVICEKCGVELALAKVRRERMGHIELASPVAHIWFLKSLPSRIGLLLDMTLRDIERVLYFEAFVVVDPGMTELERGQLLNDEAYLDAMEQYGDEFDARMGAEAIRDLLRQIDLEDEIRNLREELPTTNSETKIKKITKRLKLLEAFYESGNKPEWMIMDVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLNAPDIIVRNEKRMLQESVDALLDNGRRGRAITGTNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVIVVGPTLKLHQCGLPKKMALELFKPFIFSKLEFRGLATTIKAAKKMVEREESVVWDILDDVIREHPILLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCTAYNADFDGDQMAVHVPLTLEAQLEARSLMMSTNNILSPASGEPIIVPSQDVVLGLYYLTREKVNALGEGKIYSSAQEAQNFYEAGHLDIHAKIKIRMPKEDGETGYHLVETTVGRAILAEILPKGMPFDYINRTMTKKVISKVIDSCYRKFGLKETVIFADQLMYTGFKYATRSGASIGIEDMEIPDDKASIIEHADNEVREIESQFRSGLVTNGERYNKVIDIWSRTNELVAKSMMSKIATEEVADAKGNKVRQESFNPIFMMADSGARGSAAQIRQLAGMRGLMAAPDGSIIETPITANFREGLNVFQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDVVITEDDCGTDTGILMQPLIEGGDIVEPLHERVLGRVVASDVYIPTQTEPVVKAGTLLDEEWVEKLEKHGVDQVMVRSPITCQTRFGLCAKCYGRDLARGHLVNTGEAVGIIAAQSIGEPGTQLTMRTFHIGGAASRATAANNIQIKTKGVIRLHNIKTVTHENKNLVAVSRSGEVTIVDEFGRERERYKVPYGAVISAQDNSPVEAGQVIATWDPHTHPVISEVSGRLKFVDLIDGITMNRQTDELTGLSNIVIIDAKQRSAAGRDLRPMVKLVTDEGDDIYLAGTNVPAQYYLPVDAIVNFEDRSLVGIGDVIARIPQERSKTRDITGGLPRVADLFEARKPKDSAVMAEVSGLVNFGKETKGKRRLIINVSEDQCHEELIPKWRHISVFEGEHVERGEIIAEGALNPHDILRLLGVGALANYIVNEVQDVYRLQGVKINDKHIEVIVRQMLRKRVITFAGDSKFLVGEQVEESAMLQENDKLLAEGKQIARGTPILLGITKASLATESFISAASFQETTRVLTEAAVSGKVDELRGLKENVMVGRLIPAGTGYTYHQSRKAKRARVAAGGDSSATHTVTASDVEHALSEALNADNHEH
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: APT_TOLAT
Sequence: MNRNTLDFIQSCIATIPDYPKPGIIFRDVTSLVEHPQGFHQTIELLKEHYQSMSFDKVVGTEARGFIFGAPLAYALQLGFIPVRKPGKLPRSVLEQSYQLEYGEDCLQMHCDAIKPGEKVLVVDDLLATGGTVEATIKMIREAGGIVEHAAFVISLPDLGGEERLTAMGVNVLKLVDFPGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MLTF_ECO11
Sequence: MKKLKINYLFIGILALLLAVALWPSIPWFGKADNRIAAIQARGELRVSTIHTPLTYNEINGKPFGLDYELAKQFADYLGVKLKVTVRQNISQLFDDLDNGNADLLAAGLVYNSERVKNYQPGPTYYSVSQQLVYKVGQYRPRTLGNLTAEQLTVAPGHVVVNDLQTLKETKFPELSWKVDDKKGSAELMEDVIEGKLDYTIADSVAISLFQRVHPELAVALDITDEQPVTWFSPLDGDNTLSAALLDFFNEMNEDGTLARIEEKYLGHGDDFDYVDTRTFLRAVDAVLPQLKPLFEKYAEEIDWRLLAAIAYQESHWDAQATSPTGVRGMMMLTKNTAQSLGITDRTDAEQSISGGVRYLQDMMSKVPESVPENERIWFALAAYNMGYAHMLDARALTAKTKGNPDSWADVKQRLPLLSQKPYYSKLTYGYARGHEAYAYVENIRKYQISLVGYLQEKEKQATEAAMQLAQDYPAVSPTELGKEKFPFLSFLSQSSSNYLTHSPSLLFSRKGSEEKQN
What is the function of this protein?
Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product.  Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus.  Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase F, Murein lyase F.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane.
Protein: RL13_STAAC
Sequence: MRQTFMANESNIERKWYVIDAEGQTLGRLSSEVASILRGKNKVTYTPHVDTGDYVIVINASKIEFTGNKETDKVYYRHSNHPGGIKSITAGELRRTNPERLIENSIKGMLPSTRLGEKQGKKLFVYGGAEHPHAAQQPENYELRG
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: APT_SYNJA
Sequence: MDLRAFIRLVPDFPKPGILFRDITPLLRDPAGFRAAIEQLAAGTATMGSLDYVVGIESRGFILGAALAQHLGLGFVPVRKPGKLPPPVLSQSYSLEYGQDQLQLHAHALRPGDRVVIVDDVIATGGTAAATAQLVAQSGAEVGGFAFLIELAFLSGRKLLPPEIPTHVVMVDESN
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y102_SIRV1
Sequence: MEFEDLDVVLYVFFENPEMKSFEFEFKQLFETTESGLRYLIGVPDSRNKIKNNNEIIEEFIYYQNDDIVTKLIFYYTKGTNRIYIRKIYGWKEKRLESEDEE
What are the official names of this protein?
Uncharacterized protein 102.
Protein: DUS_RICCN
Sequence: MIKIGNIELSSNIILAPMSGVTDLEFRRLVKRFGAGLVVSEMVASRAMIVESRQSLKKSAIMRDDATSACVQLAGCEPNVIAEAAKMNEGMGAKIIDLNFGCPAKKVVGGYSGSALMKDEQLAAKIFEATVEAVKLPVTVKMRMGWDDNTKNAPTLAKIAESSGVQMITVHGRTRCQFYSGNADWDFIRSVKESVKIPVIANGDITNFAKAKEALQKSGADGIMVGRGAYGKPWLISQIDHYLKTGEEKSAPSIAEQLDIVTEHYEAILDYYGESVGVPIARKHIGWYSSGLPNSAEFRGAVNLMNDPLAVKEKIAEFYTSVMETNKLKEF
What is the function of this protein?
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.
What are the official names of this protein?
Probable tRNA-dihydrouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the Dus family.
Protein: G6PDC_TOBAC
Sequence: MVTLYSSPSTHSSGPVASYSNSSIGLYNYHHNKQIAVSSILSRKFGSLQINQKPFWNAVRMQDGAVATPPSKIENETPLKKLKNGILPVAPPKEQKDTIDFDSNKAKSTVSITVVGASGDLAKKKIFPALFALYYEGCLPEHFTIFGYARSKMTDAELRNMVSKTLTCRIDKRENCGEKMEQFLERCFYHSGQYDSLENFAELDKKLKEHEAGRFSNRLFYLSIPPNIFINAVRCASLSASSAHGWTRVIVEKPFGRDSESSAALTRSLKQYLNEDQIFRIDHYLGKELVENLSVLRFSNLIFEPLWSRQCIRNVQFIFSEDFGTEGRGGYFDHYGIIRDIMQNHLLQILALFAMETPVSLDAEDIRNEKVKVLRSMRPLQLDDVIIGQYKCHTKGDVTYPGYTDDKTVPKDSLTPTFAAAALFIDNARWDGVPFLMKAGKALHTRSAEIRVQFRHVPGNLYNKNFGSDLDQATNELVIRVQPNEAIYLKINNKVPGLGMRLDRSNLNLLYSARYSKEIPDAYERLLLDAIEGERRLFIRSDELDAAWSLFTPVLKELEDKKIVPEYYPYGSRGPIGAHYLAARYKVRWGDLV
What is the function of this protein?
Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.  The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis which are involved in membrane synthesis and cell division (By similarity).
What are the official names of this protein?
Glucose-6-phosphate 1-dehydrogenase, chloroplastic, G6PD.
What is the protein family that this protein belongs to?
Belongs to the glucose-6-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DLDH_HALVD
Sequence: MVVGDIATGTELLVIGAGPGGYVAAIRAAQNGIDTTLVEKDAYGGTCLNYGCIPSKALITGANLAHEAGNAEEMGIHADPVVDMSQLRDWKSGVVDQLTGGVEKLCKANGVNLVEGTARFKDENAVRIAHGGEGQGSETIEFEHCIIATGSRVIQIPGFDFGDEPVWSSRDALEADTVPERLVVVGGGYIGMELSTTFAKLGADVTVVEMLDDILPGYESDVARVVRKRAEELGIDMHLGEGASGWREEDDGIMVTTETEDGEENEYRADKVLVAVGRSPVTDTMDIENAGLEADDRGFLSVDDRRRTDVEHIYAVGDVVEDTPMLAHVASKEGIVAAEHVAGEPVAFDSQAVPAAVFTDPEIGTVGMTEADAEEAGFTPVVGQMPFRASGRALTTNHADGFVRVVADEESGFVLGAQIVGPEASELIAELAFAIEMGATLEDVASTIHTHPTLAEAVMEAAENALGQAIHTLNR
What are the official names of this protein?
Dihydrolipoyl dehydrogenase, Dihydrolipoamide dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECU_LACLA
Sequence: MVNYPNGRSRAYSTVPKKKKSLTELSVTKKSTSKTKGMVAFGKRGMNFEAEINATNEYYLSRGLAVIHKKPTPIQIVKVDYPQRSRAKITEAYFRQASTTDYSGVYKGHYIDFEAKETQQKTVFPLKNFHEHQIVHMSNVLAQGGIAFVLLHFARLNETYLLPSSCLITFYYEKGGLKSIPLSHIRENGYKIETNHIPRIPYLEIVNKLCEVQ
What is the function of this protein?
Endonuclease that resolves Holliday junction intermediates in genetic recombination.  Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands.  Promotes annealing of linear ssDNA with homologous dsDNA.  Required for DNA repair, homologous recombination and chromosome segregation.
What are the official names of this protein?
Holliday junction resolvase RecU, Recombination protein U homolog.
What is the protein family that this protein belongs to?
Belongs to the RecU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_MYCGE
Sequence: MDVTNILLKPVLTEKSYLNQMGELKKYVFAINPKATKTKVKLAFEIIYGVKPLKINTLIRKPVTIRNGTKYPGFSKLAKLAVITLPKGMDIAITGEKTTKKETKDQ
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: HIS4_CLOB8
Sequence: MIILPAIDIIDGKPVRLYQGDYNKKEIVADDVFETAKSFQDMGAEYIHLVDLDGAKSGSNQNHELVIKIANELNIPVELGGGIRSFETIKYLLDNGVARVILGTIAMEDEELLKKAIAIYDSKIAVGIDCKDGKVYGRGWLAASDLDYIEFAKKMENIGVKNIIVTDISKDGTLEGPNVEMLKKLKRTVSIDITASGGIKDIENIKELKNIDLYGAITGKAIYAKTLSLEKAIEISKEGR
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.