PharMolix/UniProtQA huggingface dataset:
Protein: T2R42_PONPY
Sequence: MPTELDKIFLILAIVEFIIGLLGNVFIGLVNCSEGIKNQKVFSADFILTCLAISTIGQLLVILFDSFLVGLASHLYTTYRLGKLVILLWHMTNHLTTWLATCLSIFYFFKIAHFPHSLFLWLRWRMNGMIVMLRTLSLFLLIFDSLVLKLFIDISLNIIDKSNLTLYFDESKTLYDKLSILKTLLSLTSFIPFSLSLTSLLFLFLSLVRHTRNLKLSSLGSRDSSTEAHRRAMKMVMSFLFLFIVHFFSLQVANWIFFMSWNNKYIKFVMLALNAFPSCHSFILILGNSKLRQTAVRLLSHLRNYTKTSNPLPL
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 42, T2R42, T2R55.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SYM_STAAN
Sequence: MAKETFYITTPIYYPSGNLHIGHAYSTVAGDVIARYKRMQGYDVRYLTGTDEHGQKIQEKAQKAGKTEIEYLDEMIAGIKQLWAKLEISNDDFIRTTEERHKHVVEQVFERLLKQGDIYLGEYEGWYSVPDETYYTESQLVDPQYENGKIIGGKSPDSGHEVELVKEESYFFNISKYTDRLLEFYDQNPDFIQPPSRKNEMINNFIKPGLADLAVSRTSFNWGVHVPSNPKHVVYVWIDALVNYISALGYLSDDESLFNKYWPADIHLMAKEIVRFHSIIWPILLMALDLPLPKKVFAHGWILMKDGKMSKSKGNVVDPNILIDRYGLDATRYYLMRELPFGSDGVFTPEAFVERTNFDLANDLGNLVNRTISMVNKYFDGELPAYQGPLHELDEEMEAMALETVKSYTESMESLQFSVALSTVWKFISRTNKYIDETTPWVLAKDDSQKDMLGNVMAHLVENIRYAAVLLRPFLTHAPKEIFEQLNINNPQFMEFSSLEQYGVLTESIMVTGQPKPIFPRLDSEAEIAYIKESMQPPATEEEKEEIPSKPQIDIKDFDKVEIKAATIIDAEHVKKSDKLLKIQVDLDSEQRQIVSGIAKFYTPDDIIGKKVAVVTNLKPAKLMGQKSEGMILSAEKDGVLTLVSLPSAIPNGAVIK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UT1_BOVIN
Sequence: MDDNPTAVKLDQGGNQAPQGRGRRCLPKALGYITGDMKEFANWLKDKPQALQFVDWVLRGISQVVFVSNPISGILILVGLLVQNPWCALNGCVGTVVSTLTALLLSQDRSAITAGLQGYNATLVGILMAIYSDKGNYFWWLLFPVSAMSMTCPVFSSALNSVLSKWDLPVFTLPFNMALSMYLSATGHYNPFFPSTLITPVTSVPNVTWPDLSALQLLKSLPVGVGQIYGCDNPWTGGIFLGAILLSSPLMCLHAAIGSLLGIIAGLSLSAPFEDIYAGLWGFNSSLACIAIGGTFMALTWQTHLLALACALFTAYLGASMSHVMAVVGLPSGTWPFCLATLLFLLLTTKNPNIYKMPISKVTYPEENRIFYLQSRKRTVQGPL
What is the function of this protein?
Mediates the transport of urea driven by a concentration gradient across the cell membrane (PubMed:15845882, PubMed:22733730).  Mediates the transport of urea across the cell membranes of erythrocytes and the renal inner medullary collecting duct which is critical to the urinary concentrating mechanism (By similarity).  Facilitates water transport in erythrocytes (By similarity).
What are the official names of this protein?
Urea transporter 1, Solute carrier family 14 member 1, Urea transporter B, UT-B, Urea transporter, erythrocyte.
What is the protein family that this protein belongs to?
Belongs to the urea transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Note=Restricted to the basolateral membrane in various portions of the urothelium.
Protein: MDH_DEHM1
Sequence: MPKISVIGAGNVGATLAQRLIEKDFADVVMLDVVEGIPQGKALDISQSANVLGFSHTITGSNDYAETAGSEIVVITAGIARKPGMTREELLAINQKIMTDVVSNCLKYSPEATLVVVSNPVDTMTYLAWKLSGLPRKRVVGLSGVLDGGRLATFVARELGVKPSAVTPCVMGEHGGSMVVMPRFTLVSGKPLSELVSAEKADELAKRAVNGGAEIVAFLKTGSAFYAPSASIAAMAEAIFTGSGKVMNCAAVLDGEYGLKNIVLGVPVKLGKGGLQEIITLPLDGTENARLLASAEVVKGQIAALSL
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: LIPT2_HUMAN
Sequence: MRQPAVRLVRLGRVPYAELLGLQDRWLRRLQAEPGIEAPSGTEAGALLLCEPAGPVYTAGLRGGLTPEETARLRALGAEVRVTGRGGLATFHGPGQLLCHPVLDLRRLGLRLRMHVASLEACAVRLCELQGLQDARARPPPYTGVWLDDRKICAIGVRCGRHITSHGLALNCSTDLTWFEHIVPCGLVGTGVTSLSKELQRHVTVEEVMPPFLVAFKEIYKCTLISEDSPN
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes, which catalyze essential redox reactions (PubMed:28757203).  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity).
What are the official names of this protein?
Putative lipoyltransferase 2, mitochondrial, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RS7_BACP2
Sequence: MPRKGPVAKRDVLPDPIYNSKLVSRLINKMMIDGKRGKSQTILYKSFDIIKERTGNEAMEVFEQALKNIMPVLEVKARRVGGANYQVPVEVRPDRRTTLGLRWLVNYARLRGEKTMEERLANEILDAANNTGAAVKKREDTHKMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: QUEA_PROMA
Sequence: MVIDPRDFLLSSYDYELNSSLIAQEPIEPRHNARMLHVSKRSGEGLKAFHLKVWDLLAELRAGDLLVMNDTRVLKARLKVRLRNGTFVELFLLEPKGQGRWLCLAKPAKKLRAGDCIWMESSGEESIPLKIIDQDISTGGRIVQFPELFSDRRKIEPLLEKFGEIPLPPYINRCDFKDVNRYQTRYASTPGAVAAPTAGLHLSDQFLEALSQQGIKDAKVTLHVGLGTFRPLVEENLANLHLHSEWVEVKEEVVSAIKECRDRGGRVIAIGTTTVRSLEASFLAGDGCLKPFKGEVDLVIKPGYKFGIVDGLLTNFHLPKSSLLLLVSALIGRENLLELYKEAIDQKYRFFSYGDAMFISPEGVLPSARL
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALR_CARHZ
Sequence: MRPVWAEVNLENIRHNFREVKRLARQAEAMPVIKANAYGHGAVEVAKALIAEGAKRFAVAILDEGIKLREAGIDAPVLILGYTPPEEVEKLLFYNLTPTLHHRELALAYQERLERLKKTLFYHLKIDTGMGRIGFWYEELEKIEEVLKLKNLEAEGVYTHFARADEQDLSFSKLQIERFNIVLKHLKAKGIEVKYRHAANSAAIMRLPEAHYDLVRPGIMLYGEYPSRDVPRELAHLKPALTLKARVSQVKKVPAGFTVSYGSTYVTSKATLIVSLPLGYADGYFRRLSNRGVVLINGKRWSIAGRVCMDQLMVAVDETERVNPGDEAVLLGKQGEETITAMEMADLVGTINYEILTNISYRVPRIYV
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: NA18_ANEVI
Sequence: MMNRLLVFVMLGAAFMLVVSAVDQDAYEDVNMLKRGGTPCPCDGESMSGIIWFWSCPAGWRKCGAEWPAPCCKAIG
What are the official names of this protein?
U-actitoxin-Avd7a, U-AITX-Avd7a, Av8, Neurotoxin 8.
What is the protein family that this protein belongs to?
Belongs to the sea anemone sodium channel inhibitory toxin family. Type I subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: RDRP_I80AA
Sequence: MDVNPTLLFLKVPAQNAISTTFPYTGDPPYSHGTGTGYTMDTVNRTHQYSERGRWTKNTETGAPQLNPIDGPLPKDNEPSGYAQTDCVLEAMAFLEESHPGIFENSCIETMEVVQQTRVDKLTQGRQTYDWTLNRNQPAATALANTIEVFRSNGLKANESGRLIDFLKDVMESMDREEVEITTHFQRKRRVRDNVTKKMVTQRTIGKKKHRLNKRSYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRGFVYFVETLARSICEKLEQSGLPVGGNEKKAKLANVVRKMMTNSQDTEISFTITGDNTKWNENQNPRMFLAMITYITRNQPEWFRNILSIAPIMFSNKMARLGKGYMFESKSMKLRTQIPAEMLANIDLKYFNDSTRKKIEKIRPLLIDGTASLSPGMMMGMFNMLSTVLGVSILNLGQKRYTKTTYWWDGLQSSDDFALIVNAPNYAGIQAGVDRFYRTCKLLGINMSKKKSYMNRTGTFEFTSFFYRYGFVANFSMELPSFGVSGINESADMSIGVTVIKNNMINNDLGPATAQMALQLFIKDYRYTYRCHRGDTQIQTRRSFEIKKLWDQTRSKAGLLVSDGGPNLYNIRNLHIPEVCLKWELMDEDYQGRLCNPLNPFVSHKEIESVNNAVMMPAHGPAKNMEYDAVATTHSWVPKRNRSILNTSQRGILEDEQMYQRCCNLFEKFFPSSSYRRPVGISSMVEAMVSRARIDARIDFESGRIKKEEFTEIMKTCSTIEELRRQK
What is the function of this protein?
RNA-dependent RNA polymerase which is responsible for replication and transcription of virus RNA segments.  The transcription of viral mRNAs occurs by a unique mechanism called cap-snatching.  5' methylated caps of cellular mRNAs are cleaved after 10-13 nucleotides by PA.  In turn, these short capped RNAs are used as primers by PB1 for transcription of viral mRNAs.  During virus replication, PB1 initiates RNA synthesis and copy vRNA into complementary RNA (cRNA) which in turn serves as a template for the production of more vRNAs.
What are the official names of this protein?
RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 1, PB1, RNA-directed RNA polymerase subunit P1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses polymerase PB1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: ATPA_GLAP5
Sequence: MQLNSTEISELIKKRIAQFNVVSEAQSTGTIVSVSDGVIRIHGLADVMQGEMIALPGNRYAIALNLERDSVGAVVMGPYADLAEGMEVKCTGRILEVPVGRGLLGRVVNTLGQPIDGKGEIDNDGFSPIEVIAPGVIDRQSVDQPVQTGYKAVDSMVPIGRGQRELIIGDRQTGKTALAIDAIINQRDSGIKCIYVAIGQKASTISNVVRKLEEHGALQNTIVVVASASESAALQYLAPYAGCAMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVNADYVERFTNGAVKGQTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETSFFNAGIRPAVNPGISVSRVGGSAQTKLVKKLAGGIRTALAQYRELAAFAQFASDLDDATRKQLSHGQKVTELLKQKQFEPMSVAQLGLSLAAAEFGYLDDVEVERVGSFESNLLAYANANYAEFMKDLSKSGDFNDTIKAKLIEILDSFKKNSAW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TPS4_MATCR
Sequence: MAITHYQMASFQSSFHFCMLRKTLRQKSSLHFAKRCEATNKIFQTHGSVAIYQKTLWTHDLIDGLETDFLINRKEKVNELEVNVARMFMDYENGDISNLELLELIDNIERLGLGHRFQTNMKRVLDKIATVNENSLGLKEEEEEEEEEEDNLHALSLKFRILRQSGYRVSQDFQRKFKESRGGLTGGLKELLSIYEASYLSLEGEPDLHEAKLFATEKLLKLTGHENEAMKDHVNHALDIPLYRRMLRLEARWYIDAYGKRKDANKQLLELAILDFNIVQSAHKRDLQEVSKWWEKTGLVRKLDFIRDRLMECFFWSVGMVFEPQYYTCRVELTKIATLITTIDDIYDVYGSLNELKVFTHAVKRWDINAVENMPEYLQLGFLALYNTINEMGYETLSAQGINIIPNLARVWGELLEAFLVEAEWTHNNYMPTFKDYLDNAWRSVSGMVLLTHGYFLMNQDVKDDAIESLENFHDLFKWSSMLFRLYNDLAALADEIDKDKSPNAISCYMYEHSVSEEVAREHVKTLIDKAWMKMIEARIACSEHMTDPLIDMAINLARVSSCMYQYGDGIKDPEARTKDRVMSIIIKPFDTSEIP
What is the function of this protein?
Monoterpene synthase involved in the biosynthesis of (E)-beta-ocimene as the major product and trace amounts of (Z)-beta-ocimene.  Can only accept geranyl diphosphate as substrate.
What are the official names of this protein?
(E)-beta-ocimene synthase, chloroplastic, Terpene synthase 4.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsb subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PLB2_CANGA
Sequence: MQLSVLIASVLAAGAAVDAASYTPQNVSCPDNANFIRNAADGLSPAEKEWLKKRDPITRDALQTFLRRAFANVSTEITSALFNDTENVPKLGIAVAGGGYRAMFVGAGAFAAMDNRTDGANEHGLGGLLQAATYMAGLSGGNWLTGTLAYNNFTSVQQILEEGDKADAIWNITNSFLNPYDKDFSKTLARWTAIGSQVQGKRDAGFNVTITDLWSRALAYGWFPTLPNAGAGLTWSSLRDNEIFMNGEMPMPISVADGRYPGTTVINLNATVFEMTPFEIGSWDPSLNAFSDIKYLGTQVTDGKPETERCINGFDDASFIMGTSSSLFNEFTMSNDSAVAYTYLNTLSSTLVKGIDKENNDIAMYAPNPFKGSKYVDSNYTTSIVDSDSLFLVDGGEDLQGIPFVPLLKQERDLDIIFAIDVDTETSDNYPAGGPMMKTYERQFSKQGKGMAFPYVPDMTTFVNLGLGGKPSFYGCDANNLTDLEYIPPLIVYIPNSYHSFESNVSTFKLNYNYSERVGMIRNAFEATTRNNLTEDADYVTCVGCAIIRRKQQSLNLTLPDICDKCFTNYCWNGTIDNTPTKLLTPNNQDPAAISSAIAAVTDDSPIGALLNTGSGTKSNSSSKTNSTLVTSSRATSTGTLISNSSSNSTVSSTAARSSTSSTAKKNAGSVLKLEFSKSASVMVAIAAAAVASLI
What is the function of this protein?
Catalyzes the release of fatty acids from lysophospholipids (By similarity).  Phospholipase B may well contribute to pathogenicity by abetting the fungus in damaging and traversing host cell membranes, processes which likely increase the rapidity of disseminated infection (By similarity).
What are the official names of this protein?
Lysophospholipase 2, Phospholipase B 2.
What is the protein family that this protein belongs to?
Belongs to the lysophospholipase family.
What are the subcellular locations of this protein?
Secreted. Secreted, cell wall.
Protein: MDTA_SALTY
Sequence: MKGSNTFRWAIAIGVVVAAAAFWFWHSRSESPTAAPGVAAQAPHTASAGRRGMRDGPLAPVQAATATTQAVPRYLSGLGTVTAANTVTVRSRVDGQLIALHFQEGQQVNAGDLLAQIDPSQFKVALAQAQGQLAKDNATLANARRDLARYQQLAKTNLVSRQELDAQQALVNETQGTIKADEANVASAQLQLDWSRITAPVSGRVGLKQVDVGNQISSSDTAGIVVITQTHPIDLIFTLPESDIATVVQAQKAGKALVVEAWDRTNSHKLSEGVLLSLDNQIDPTTGTIKIKARFTNQDDTLFPNQFVNARMLVDTEQNAVVVPAAAVQMGNEGHFVWVLNDENNVSKKRVKIGIQDNRNVVISAGLSAGDRVVTDGIDRLTEGAKVEVVEPQTTVADEKSPSRHEGQKGARA
What are the official names of this protein?
Multidrug resistance protein MdtA, Multidrug transporter MdtA.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS6_MICAN
Sequence: MSNNYETLYILRPDLGEEVVQQQVERYRTLITEHSATDIQVKVWGKKRLAYPIKKLNDGVYVQMNYQASGKQVAPMERAMRLSDEVIRYLTLKLDRVVAPPADLSPLTEIPPSPITEAVVEDDGISAED
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: Y905_PSEPG
Sequence: MLLHIPGLFDADELARIREALEQADWADGKVTAGYQSAKAKHNLQLPEGHALAKEIGSALIDRLWKTPRFMSAALPHKVFPPLINCYREGGNFGFHIDNALRQPKGSPERVRTDLSSTLFLSDPDSYDGGELVIQDTYGVQQVKLAAGDLVLYPGTSLHKVNPVTRGQRYAAFFWAQSLVREDSQRALLFEMDNAIQQLTADVPDHPSLLQLTGTYHNLLRRWAEV
What are the official names of this protein?
PKHD-type hydroxylase PputGB1_0905.
Protein: Y399_RHIWR
Sequence: MTKAGMTKAGEPRRILFVTGMSGSGKKTALTALEDMGWETVDNLPVSLLERLLAASPAEGSIDEGRPLALGIDSRTRDFDSRGVVRRVRSLRDGGRDASILFFDCSNTELSRRYSETRARHPLARDRQVEDGISYERELLAPLREAADELIDTTDSSTNELQALLRRRFGDSAGTGTTLTVMSFAFSRGVPRDADLMFDMRFLRNPHWVPELKPHSGLDPDVGAYIAGDPIYPEARARIEELILLLLPRYETEGKSYVTIAIGCTGGKHRSVHFAETLASRLRQEGFSPTVRHRDLTRQKSNAEESTVPGVGS
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Swit_0399.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: PYRE_LACLA
Sequence: MSISKAIAADLLEIKAVSLSPSQPFTWASGIKSPIYTDNRVTLAYPEVRSQIEGAFAELIKAEFPEVEVIAGTATAGIPHGAIIADYLKLPFAYIRSKPKDHGAGNQVEGRVTKGQKMVVVEDLISTGGSVLEAVAAAEREGADVLGVVAIFTYELEKANRKFADAGVKLATLTTYSELIEIAKETGYVTKEELELLKKFKENQETWQN
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: FPG_STRGG
Sequence: MPELPEVEVVRRGLERWVSGRTVSEVEVLHPRAVRRHLAGGVDFAARLAGARFGAAMRRGKYLWVPIDEASASLLGHLGMSGQLLVRPADAPDEKHLRIRMRFDDALGTELRFVDQRTFGGLSLHANTPDGLPETIAHIARDPLDPLFDDAAFHTALRLRRTTVKRALLDQSLISGVGNIYADEALWRARLHYDRPTATLTRPRSAELLGHARDVMNAALAQGGTSFDSLYVNVNGESGYFDRSLDAYGREGEPCHRCGTPMRRRAWMNRSSYYCPRCQRPPRASS
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: RL35_WOLPP
Sequence: MTKIKLKTKSSVKKRFHLTAKGKVISTQSGKRHGMVKRSKSNIRNQRGTTILNKSDSRIVKLYMPYGI
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: TRPD_CUPPJ
Sequence: MRLLDTATPSVSSIPIAPHATQPTETAMTITAQEALTRCIEHREIFHDEMLHLMRQIMQAQISPVMAAAILTGLRVKKETIGEISAAAQVMREFANKVEVTDRENFVDIVGTGGDGSHTFNISTASMFVAAAAGAKIAKHGNRGVSSKSGSADVLEALGVNIMLTPEQVGQCIAQTGIGFMFAPTHHPAMKNVAPIRKEMGVRTIFNILGPLTNPADAPNILMGVFHPDLVGIQVRVMQRLGAKHALVVYGKDGMDEVSLGAATLVGELKDGEVREYEIHPEDFGLSMISNRGLKVADAVESKAMLLEALGNVPGTPREIVSLNAGTALYAANVADSIEDGIRRAREAIASGAAREKLDHFVRATQQFK
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: RT28_MOUSE
Sequence: MAALCRSHAGTAGSRFLRALVFSKPLRNASTESGSESATHDSSAPRARSGGFASALERHSDLQRKAELRLESPKPVESFASMLRHSPLTQLGPAKDKLVIGRIFHIVEDDLYIDFGGKFHCVCKRPDVDGEKYQRGTRVRLRLLDLELTSRFLGGTTDTTILEADAVLLGLQEIRDSKSREEQPSK
What are the official names of this protein?
28S ribosomal protein S28, mitochondrial, MRP-S28, S28mt.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS1 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GON2_ORYLA
Sequence: MSRLVLLLGVLLYVGAQLSQAQHWSHGWYPGGKRELDSFEVSEEMKLCETGECSYMRPQRRSFLRNIVLDALARELQKRK
What is the function of this protein?
Stimulates the secretion of gonadotropins.
What are the official names of this protein?
Progonadoliberin-2, Chicken-type II gonadotropin-releasing hormone, Progonadoliberin II, cGnRH-II.
What is the protein family that this protein belongs to?
Belongs to the GnRH family.
What are the subcellular locations of this protein?
Secreted.
Protein: KTHY_SYNJB
Sequence: MFITLEGGEGVGKTTQQALLVERLRQEGYACLCTREPGGTALGKTLRELLLHGDPFSPLAELLLYAADRAEHVSKVIAPALAAGQVVVCDRFTDSTLAYQGYGRGLDLEKIRQLNHLATGGLQPHLTLWLDLPPEVGLARAKARDRLEQERLEFHRRVYQGFQALAAAEPQRIVRISAQGSPAEVAARLWSVVEPRLPLATAGREP
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: KDSA_ECO8A
Sequence: MKQKVVSIGDINVANDLPFVLFGGMNVLESRDLAMRICEHYVTVTQKLGIPYVFKASFDKANRSSIHSYRGPGLEEGMKIFQELKQTFGVKIITDVHEPSQAQPVADVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQFVSPGQMGNIVDKFKEGGNEKVILCDRGANFGYDNLVVDMLGFSIMKKVSGNSPVIFDVTHALQCRDPFGAASGGRRAQVAELARAGMAVGLAGLFIEAHPDPEHAKCDGPSALPLAKLEPFLKQMKAIDDLVKGFEELDTSK
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTLF_BORPA
Sequence: MMAARMMAAGLAATALSAHAFRIPTPGEQDARIQTVPYHPEEVVLVRAWNGYVTRIVFDEQEKIIDVAAGFADGWQFSPEGNVLYIKAKSFPAQGSPAQAPEPGLWNTNLLVKTDRRLYDFDLVLASADAATPQALQRSRMAYRLQFRYPAAPQAASRASPVGPAVPAGALNRRYAMQVGNGSDGIAPIAAYDDGRHTWLTFRPGQPFPAVFAVAPDGTETLVNLHIDNQSLVIHRVAPVLMLRSGASVIRIVNQNGDASASPAFECHAEPAL
What are the official names of this protein?
Type IV secretion system protein PtlF homolog.
What is the protein family that this protein belongs to?
Belongs to the TrbG/VirB9 family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: NURA_SULAC
Sequence: MIDKAYEELIKMKEKIMRDSYTIHKELSESVESILNELWINYSPESVEHSKKLLAIDGGMWVKETRQGVIFIVNAKAIVFEGINEINSEGKVLVHIFSPGNYAKERIELLMQLLELQLALKLVENVDYVLLDGSFSKKLGRHKSELKVDLLDDIVSIDKILSLEEKDEDNMLRFLIAENQLVLSELVSRYKDKLLFISKNSKSSDLFKQAYSDITILELFTQNCGYSKILEKKIDENYILSRKASKLLSGLNYYFTNLRLEPSERLFRLDFFNADKIFEYLKVLKPVSLKGYPYPLIKVHKDVRVGKEDRERIYSILEMKRKDISWWPSQFY
What is the function of this protein?
Involved in DNA double-strand break (DSB) repair (PubMed:12052775).  Acts probably with HerA to stimulate resection of the 5' strand and produce the long 3' single-strand that is required for RadA loading (By similarity).  Exhibits both single-stranded endonuclease activity and 5'-3' exonuclease activity on single-stranded and double-stranded DNA (PubMed:12052775).
What are the official names of this protein?
DNA double-strand break repair nuclease NurA, Nuclease repair of Archaea.
What is the protein family that this protein belongs to?
Belongs to the NurA family.
Protein: RITA1_AILME
Sequence: MKTPVELAVSGIQTLPLQHRCRGSHRVKARASYVDESLFGSPAGTRPTPPDFDPPWVEKANRTSGVGTGTSRASGANGSCETTSSSGSTPTLTPRKKNKYRLISHTPSYCDESLFGSRPEGTNWEGPWMAKGDAAKLHSLFWTPPATPRGSHSPRPRETPLRAIHPAGPSKTEPKVAADSQKLSTDGLDSPHPLRRERSHSLTHLNVPRTGRPPTSGPHTNGPRDPRPSPSGVTLQSPLVTPRARSVRISVPATPQRGGATQKPKPPWK
What is the function of this protein?
Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway.  Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription.  May play a role in neurogenesis (By similarity).
What are the official names of this protein?
RBPJ-interacting and tubulin-associated protein 1, RBPJ-interacting and tubulin-associated protein.
What is the protein family that this protein belongs to?
Belongs to the RITA family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Shuttles rapidly between the cytoplasm and the nucleus. The function of centrosome localization is still unclear (By similarity).
Protein: MMAC_CAEEL
Sequence: MVTEMSHAESIKRVVDQKLSSHEGFESHMFKIGSYNEAVGESSPFALPYDDSTMALLILSTPDMFDVAFRKWVVQKTMDFGSFDEVCEMVSSPIQSFLEDRLEIMSEKLRKVEENFEILHDYSMTPQRRPKILMQTCGHVAGAAFYYQPCHFQEDGVTWPPAGRMGPNLKFIGLSLHPIYGGHFAFRSVLIFPNVKIPEFCEKEPRPILTASEDVRTALEKFNYNWKDSGFRDFGNPTRRYSTTQMEFFGRPVAERWEVLRPWVDGGAKNID
What is the function of this protein?
Catalyzes the reductive dealkylation of cyanocobalamin to cob(II)alamin, using FAD or FMN as cofactor and NADPH as cosubstrate.  Can also catalyze the glutathione-dependent reductive demethylation of methylcobalamin, and, with much lower efficiency, the glutathione-dependent reductive demethylation of adenosylcobalamin.  Under anaerobic conditions cob(I)alamin is the first product; it is highly reactive and is converted to aquocob(II)alamin in the presence of oxygen.  Binds cyanocobalamin, adenosylcobalamin, methylcobalamin and other, related vitamin B12 derivatives.
What are the official names of this protein?
MMACHC-like protein, Cobalamin deficiency protein 1, Cyanocobalamin reductase (cyanide-eliminating).
What is the protein family that this protein belongs to?
Belongs to the MMACHC family.
What are the subcellular locations of this protein?
Cytoplasm.