PharMolix/UniProtQA huggingface dataset:
Protein: MNHC1_STAA2
Sequence: MEIIMIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANLFLITMGGLKHGTVPIYEANVKSYVDPIPQALILTAIVIAFATTAFFLVLAFRTYKELGTDNVESMKGVPEDD
What is the function of this protein?
Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.
What are the official names of this protein?
Na(+)/H(+) antiporter subunit C1, Mnh complex subunit C1.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GPR82_MOUSE
Sequence: MTNNSTCIQPSVISTTALPVTYIFLFIIGLFGNSLAQWVFLTKIGKKTSTHIYLANLVTANLLVCTAMPFMGIYFLRGFYWKYQSVQCRLVNFLGTLSMHVSMFVSLLILSWIAISRYATLMKKESKQEATSCYERMFYGHVLKRFRQPNFARTMCIYIWGVVLVIIIPVTLYYSVVEATEEGQSQCYNRQMELGARPSQIAGLIGTTFIGFSFLVVVTSYYSLVSHLRRVRTCTSITEKDLTYRSVKRHLLIIQVLLVVCFLPYSIFKPIFYVLHQREGDCQQLNYLIEAKNILTCLASARSSTDPIIFLLLDKTFKKTLYGLLTKS
What is the function of this protein?
Orphan receptor.
What are the official names of this protein?
Probable G-protein coupled receptor 82.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PDPFA_DANRE
Sequence: MAAIPSSGSLIATHDYYRRRIGSTSSNSSCSSSEYTGEVIPHPPGLARQDSGHWWSSFFFGKQNQMGTPNGFESQQKTGTYTVTNGQVTCVAREIVMKRHLSESSDSGKEPGSPLPS
What is the function of this protein?
Probable regulator of exocrine pancreas development.
What are the official names of this protein?
Pancreatic progenitor cell differentiation and proliferation factor A, Exocrine differentiation and proliferation factor A, Exocrine differentiation and proliferation factor.
What is the protein family that this protein belongs to?
Belongs to the PPDPF family.
Protein: PLK4_CULQU
Sequence: MLNNFGECIEDFEVFELLGKGGFASVYRAKCCRTGILVAIKMIDKKLMQSSGMANRVRQEVSIHSRLKHPSILELYTFFEDANFVYLVLELAENGELQRYLRDTKKTFNEYEAATVLKQVVEGLLYLHSHQILHRDMSLANLLLTKEMTVKICDFGLATQLSRPDEKHMTLCGTPNYISPEVASRASHGLPADVWGLGCMLYTFLVGRPPFDTDGVKSTLTKVVMSNYTLPSHISQEARDLIDRLLKKNPAERIKLDQVPLHPFMQKASSFEKCQGGTLASSDSGIMTISSGNRSNIPSNYSQERYQPPVQMPLRYQPISEDFQESILPTRPQSAAYGRPQTSDFYSGFSGDQQQRPSTAQPPFVHHMNQISLLQHKRIDIPPLTTARLQPNRHKTKNAILSIQPNGEVVLEFIKYKSRAKADRVVDVCRISSDGLRFVLYHPDGGKGVAVKDEPPDLPPGGADAIFSYENLPEKHWKKYAYAARFVQMVKAKTPKITYYSERAKCQLMETLEDYEANFYSGTKVIKSLHEGTKIVDSTGRTFKDTTATLNTALTMEFEHFQQTFDHCLNIEQALSAIHTGNTFPLIIGRRPATATSNHENSVSTPQTPHHNPHQLSSFAMSVNSAATTNSRRLPCPKAAPSFSSNVATKKCTIPGVGTAVQLSQGVVQVQFVDGATLSLIPIEQGGGVTFSPCFGTPLQHYSAQQQQDDPASLPGTLRDKLGQMSLVLRELNAAPVPSIPFNFLEGTALSPRTPLTRFLR
What is the function of this protein?
Serine/threonine-protein kinase that plays a central role in centriole duplication.  Able to trigger procentriole formation on the surface of the mother centriole cylinder, leading to the recruitment of centriole biogenesis proteins.  When overexpressed, it is able to induce centrosome amplification through the simultaneous generation of multiple procentrioles adjoining each parental centriole during S phase (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase PLK4, Polo-like kinase 4, PLK-4, Serine/threonine-protein kinase SAK.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole.
Protein: MIFH_TRITR
Sequence: MPIFTFSTNVPSENISVDFLKSTSKLIAGMLGKPESYVAVHINGGQKITFGGTDAPAGFGQLLSLGGVGGEKNRSHSAKLFKHLTDGLGIPGNRMYINFVDMRGSDVGYNGSTF
What is the function of this protein?
Tautomerization of the methyl ester of L-dopachrome.  Inhibits migration of human peripheral blood mononuclear cells (By similarity).
What are the official names of this protein?
Macrophage migration inhibitory factor homolog, MIF, L-dopachrome isomerase, L-dopachrome tautomerase, Phenylpyruvate tautomerase.
What is the protein family that this protein belongs to?
Belongs to the MIF family.
What are the subcellular locations of this protein?
Secreted.
Protein: PLSB_HAEIE
Sequence: MANFINMYRQLLSLPLSALVKNNPIPANPIEELSLNIHQPIVYVLPYTSQTDFVIFRRNCLALGLPDPAEKNEINGVKLPRYVYLDEGRRIFKSKGAKDETTTIFNKYLELHRTSESLDVQLIPVSVLWGRSPGQEDKSDLPNLRLLNGIQKTFAAIWFGRDTFVRFSQAVSLRYMVVEHGSDEKIAQKLARVAKMHFAKQRISATGPRLPNRQAMFNKLLQSEAIRRAIEDEAKSKNISIEKAQKEAYKILDEIAADVSHSSLRAVDRFLRWLWNKLYSGIDVQNSNRVRKLALEGHEIVYVPCHRSHIDYLLLSYVLYHQGLVPPHIAAGINLNFWPIGRMFRSWGAFFIRRTFKGNRLYSAIFREYLSELFHRGYSVEYFIEGGRSRTGRLLAPKTGMMSMTLQALQHSQTRPISIVPVYVGYEHVLEVDTYAKELRGAAKEKENAGLVLRVIKKLRNLGQGFVNFGEPITLSNYLSQHFPDWKEQNHEEKPQWFTPAVNNISKQVMININKAAAVNSMNLVGTALLSSRQRALSREQLLEQLSSYQQLLQNVPYSTDVVLPNVTPQAMLEHVLALDRIGVLIEKDNFGEIVRLERSSAVLMTYYRNNIQHLFVLPSLVASIILHYEAIQKDLLLDAIRKIYPFLQGELFLHFNEDELNVQIHQIINEFARQSVINSNDNFLSINKSKVRILQLWSAGTREILQRYYITVTILQKQPAISRAELEKESQLVAQRLSVLHGINAPEFFDKAVFSSFIANLKEQRYFDESSYTVLDKIEELASTLSHLISTEICLTVKGTIEKSEDLSS
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, GPAT.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ENO_SALA4
Sequence: MSKIVKVIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVGAVNGPIAQAILGKDAKDQAGIDKIMIDLDGTENKSNFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKGKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: TREA_DICDI
Sequence: MDFLNKKIQKILFICILSFLIVNLTKSEISEVKDVSKFLSVGGGGTGGCQHPIYCNGTLLKTIQLTQVFNDSKTFVDMPMRTSIENVNELFNQLLLNTSKNGGPNKEELAAFLSENFYPAGYEVEPVTPVDWVPNPSFLDEITDPNLVDFARSIHGKWLELTRVFNTSGLCDGCYSSIPVNNPFVIAGSRFREFYYWDSYWIIQGLLVSDMTTTAKGMLRNFGDMITEFGFIPNGGRIYYLNRSQPPLFTQMVNKYFEATNGSDIEFLQEILPILDQEYQWWMTHRTTELTNGETGESVILNLYNVSNNSPRPESYYEDFTDAQSFSSVEEKDYFYSSIASGAESGWDFSSRWMSPSDNTNLTTIQTVDVVPVDLNSILYLNEKILSSFHRTLGNNSMAVYYQAQSESRVDAMQQVFFNEDTYQWNDYNLKTSTNNEAWYTSNILPLFADIQSSIDMDNQEIDLIFKSLANVLIAYPGGVPTSLISAQSLQWDGLNVWPPLQYWIIESIMTPNTTFSNMIGKNLIDRWITTNFCGWNSTLESEGGMMFEKYNANYIGVPGGGGEYVVQNGFGWTNGVDLYLLKKYGKSITLNSC
What are the official names of this protein?
Trehalase, Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 37 family.
Protein: SSUD_BACVZ
Sequence: MEILWFIPTHGDGRYLGTQTGGRTADHLYFKQVAQAADRLGYTGVLLPTGRSCEDPWLTAAALAGETSDLKFLVAVRPGLMQPSVAARMASTMDRLSDGRLLVNVVAGGDPYELAGDGMFISHDERYKATEEFLTVWRGLMRGETVTYEGDHIKVENSNLLFPPKQSPHPPLYFGGSSQAGIEAAAKHTDVYLTWGEPPEQVKEKIETVKKQAAKEGRTMRFGIRLHVIVRETEEEAWEAAERLISHLDEETIAKAQAALRRADSSGQKRMAGLHNGDRSKLEISPNLWAGIGLVRGGAGTALVGDPQTVATRILEYQALGIESFIFSGYPHLEEAYYLAELVFPLLPFQNERTKKLERRLGEAMGNDHFARGKKAKV
What is the function of this protein?
Catalyzes the desulfonation of aliphatic sulfonates.
What are the official names of this protein?
Alkanesulfonate monooxygenase, FMNH2-dependent aliphatic sulfonate monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the SsuD family.
Protein: FAD2B_CALOF
Sequence: MGAGGRMSDPSEGKNILERVPVDPPFTLSDLKKAIPTHCFERSVIRSSYYVVHDLIVAYVFYYLANTYIPLIPTPLAYLAWPVYWFCQASILTGLWVIGHECGHHAFSDYQLIDDIVGFVLHSALLTPYFSWKYSHRNHHANTNSLDNDEVYIPKRKSKVKIYSKLLNNPPGRVFTLVFRLTLGFPLYLLTNISGKKYGRFANHFDPMSPIFNDRERVQVLLSDFGLLAVFYAIKLLVAAKGAAWVINMYAIPVLGVSVFFVLITYLHHTHLSLPHYDSTEWNWIKGALSTIDRDFGFLNRVFHDVTHTHVLHHLISYIPHYHAKEARDAIKPVLGEYYKIDRTPIFKAMYREAKECIYIEPDEDSEHKGVFWYHKM
What is the function of this protein?
Converts linoleic acid into a conjugated octadecatrienoic acid, probably calendic acid.
What are the official names of this protein?
Delta(12) fatty acid desaturase DES8.11, (8,11)-linoleoyl desaturase, CoDes8,11.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL29_DEHMB
Sequence: MNISDIRGLSDTEIKKKLEDSHKELFELRLKLSTRQLVNHRELPRVKNDIARILTVMRERELQIR
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: PSAJ_POPTR
Sequence: MRDLKTYLSVAPVISTLWFGSLAGLLIEINRFFPDALTFPFFSF
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX, PSI-J.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CC149_XENLA
Sequence: MANQLRERHQSLKKKYGELIDGDPSVPPEKRKQVNLAQLLGDSREKCKKMESEIKELQQRLGEVQGDNKLLRMTIAKQRLGDDEVGKRHFAPHEREDLVLQLEKAKEQIEAFEHDLQASLDELQDVKQERSFFQDKAERLNQELNHVLGGHEKRIIDIDALCMENRYLQERLKQVQEEVNLQKSNLVKYKNALEKRRNSKSNTKLSSSALTGVLSAKQVQELLSEEHGCSLPATPQSVSDLKSLATALLETIHEKNMVIQHQRQTNKILGNRVAELEKKLRTLEVSGLWSLPGGRDTITLSNPSSPSRGPKSLIPAFTDVPHHKPLTNEEHGQPGVELGSPALDEGSDNEAAKQLANSQVPLGNTYDNTYLHPFIPLLCQENEDLERQGPEIAKMTQELTAGEIEETSFEIPPDSQSTASSQENHDNLQSPFSSPEPSGAMSKKHPDISLGDENIVPVPQECADEITAGSNVNQCTEAQHDNKDCWEIEDCDSSEKAANNSCELIERCNRLNESVS
What are the official names of this protein?
Coiled-coil domain-containing protein 149.
What is the protein family that this protein belongs to?
Belongs to the CCDC149 family.
Protein: TOP3A_HUMAN
Sequence: MIFPVARYALRWLRRPEDRAFSRAAMEMALRGVRKVLCVAEKNDAAKGIADLLSNGRMRRREGLSKFNKIYEFDYHLYGQNVTMVMTSVSGHLLAHDFQMQFRKWQSCNPLVLFEAEIEKYCPENFVDIKKTLERETRQCQALVIWTDCDREGENIGFEIIHVCKAVKPNLQVLRARFSEITPHAVRTACENLTEPDQRVSDAVDVRQELDLRIGAAFTRFQTLRLQRIFPEVLAEQLISYGSCQFPTLGFVVERFKAIQAFVPEIFHRIKVTHDHKDGIVEFNWKRHRLFNHTACLVLYQLCVEDPMATVVEVRSKPKSKWRPQALDTVELEKLASRKLRINAKETMRIAEKLYTQGYISYPRTETNIFPRDLNLTVLVEQQTPDPRWGAFAQSILERGGPTPRNGNKSDQAHPPIHPTKYTNNLQGDEQRLYEFIVRHFLACCSQDAQGQETTVEIDIAQERFVAHGLMILARNYLDVYPYDHWSDKILPVYEQGSHFQPSTVEMVDGETSPPKLLTEADLIALMEKHGIGTDATHAEHIETIKARMYVGLTPDKRFLPGHLGMGLVEGYDSMGYEMSKPDLRAELEADLKLICDGKKDKFVVLRQQVQKYKQVFIEAVAKAKKLDEALAQYFGNGTELAQQEDIYPAMPEPIRKCPQCNKDMVLKTKKNGGFYLSCMGFPECRSAVWLPDSVLEASRDSSVCPVCQPHPVYRLKLKFKRGSLPPTMPLEFVCCIGGCDDTLREILDLRFSGGPPRASQPSGRLQANQSLNRMDNSQHPQPADSRQTGSSKALAQTLPPPTAAGESNSVTCNCGQEAVLLTVRKEGPNRGRQFFKCNGGSCNFFLWADSPNPGAGGPPALAYRPLGASLGCPPGPGIHLGGFGNPGDGSGSGTSCLCSQPSVTRTVQKDGPNKGRQFHTCAKPREQQCGFFQWVDENTAPGTSGAPSWTGDRGRTLESEARSKRPRASSSDMGSTAKKPRKCSLCHQPGHTRPFCPQNR
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.  The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils.  Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.  As an essential component of the RMI complex it is involved in chromosome separation and the processing of homologous recombination intermediates to limit DNA crossover formation in cells.  Has DNA decatenation activity (PubMed:30057030).  It is required for mtDNA decatenation and segregation after completion of replication, in a process that does not require BLM, RMI1 and RMI2 (PubMed:29290614).
What are the official names of this protein?
DNA topoisomerase 3-alpha, DNA topoisomerase III alpha.
What is the protein family that this protein belongs to?
Belongs to the type IA topoisomerase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: FMT_CHLSY
Sequence: MRILFLGSPSFAVHALEALVAAGHEIVGVVTQPDRPAGRDRRLTPPPVKIAAMAHNLPVLQPETLRDPTVVETLSALQPEVGVVAAYGEILRRAVLSIPPLGYLNIHPSLLPLYRGPTPVAGAILAGETVTGVTIMLLDPSMDSGPILAQAVVDLPPTARAGQLTDELFRIGADLLVQVLPRYARGEIEPRPQDHSRATVTKMLKKEDGRIDWSLPAIVIERMTRAYDPWPGAYTFWRGQPLRIIKAAVASADGTNVPGTVIGRSGSGHPLVQTGSDALELIEVQPASRRPMSGSAWLAGVHADNIRLGE
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: MTOX_SHIFL
Sequence: MKYDLIIIGSGSVGAAAGYYATRAGLNVLMTDAHMPPHQHGSHHGDTRLIRHAYGEGEKYVPLVLRAQTLWDELSRHNEDDPIFVRSGVINLGPADSAFLANVAHSAEQWQLNVEKLDAQGIMARWPEIRVPDNYIGLFETDSGFLRSELAIKTWIQLAKEAGCAQLFNCPVTAIRHDDDGVTIETVDGEYQAKKAIVCAGTWVKDLLPELPVQPVRKVFAWYQADGRYSVKNKFPAFTGELPNGDQYYGFPAENDALKIGKHNGGQVIHSADERVPFAEVASDGSEAFPFLRNVLPGIGCCLYGAACTYDNSPDEDFIIDTLPGHDNTLLITGLSGHGFKFASVLGEIAADFAQDQKSDFDLTPFRLSRFQ
What is the function of this protein?
Catalyzes the oxidative demethylation of N-methyl-L-tryptophan.
What are the official names of this protein?
N-methyl-L-tryptophan oxidase, MTOX.
What is the protein family that this protein belongs to?
Belongs to the MSOX/MTOX family. MTOX subfamily.
Protein: TRPA_RHIE6
Sequence: MTARMDKRFAELKAEGRPALVTYFMGGDPDYDTSLGIMKALPEAGSDIIELGMPFSDPMADGPAIQLAGQRALKGGQTLKKTLQLAADFRKTDDATPIVMMGYYNPIYIYGVEKFLDDALTAGIDGLIVVDLPPEMDDELCIPAIRKGINFIRLATPTTDEKRLPAVLKNTSGFVYYVSMNGITGSALPDPSLVSGAVQRIKQHTELPVCVGFGVKTAEHAKVIGGSADGVVVGTAIVNQVATSLTKDGKATADTVQAVATLVRGLSSGTRSARLVAAE
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: ATL68_ARATH
Sequence: MSTATLVVFPPPPPVPIPTYITSLGLGYSIAIALGFLVLISTIILSSYICCRASRLRFSASAANANANASFSDRGVIVPRIIFVAEDDDLESGNVVVGGLDHSVINSYPKFHFTKDITAVVNGDGFHDGEGRETTCSICLCEYMEEEMLRMMPECKHYFHVYCLDAWLKLNGSCPVCRNSPLPTPQSTPQSTPLSEVVPLSQYAADRRRSRR
What are the official names of this protein?
RING-H2 finger protein ATL68, RING-type E3 ubiquitin transferase ATL68.
What is the protein family that this protein belongs to?
Belongs to the RING-type zinc finger family. ATL subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: NPY2R_SHEEP
Sequence: KMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKQISFLIIGLAWGVSALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKGIYGTVYSLLSLLILYVLPLGIISFSYARIWSKLKNHVSPGAAHDHYHQR
What is the function of this protein?
Receptor for neuropeptide Y and peptide YY.
What are the official names of this protein?
Neuropeptide Y receptor type 2, NPY2-R, NPY-Y2 receptor, Y2 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ACSA_SCHPO
Sequence: MTKNPVDHTLIIEPPVRLHGDPTVPKPNIASLDEYKRMYEESINDPSTFWGNMARDMMTWDKQFSTVVQGSIDKADSAWFADGAISPCYNLVDRHAIARPDAVALIYEADEPNQGRYITYRELLASVSQCAGALQSMGVGMGDRVAIYMPMIPETIIAMLAIVRLGAIHSVIFAGFSAESVADRVNDSECKVIITADESHRGGKRIPLKGVVNKALTECPTIKKVLVFQRSAEPTASMVEGRDVWWHDIIPKFPRYCPPAVVNPEHPLFLLYTSGSTGKPKGVVHCTGGYLLGAAATCKYVFDLHPTDRMGCAGDVGWITGHTYIVYGPLMLGAATLVFESTPAYPDYSRYWSVVERHRLTQWYIAPTAIRLLQRAGNEFVKHDRSSLRVLGSVGEPIAPESFMWYYEVVGEKRCAVADTYWQTETGSHIVTSLGPVTPMKPGSATLPFFGIDAVIIDPLTGKIIEGNDVEGVLAIRSPWPSAARTVWRGHDRYIDTYLKPYPGFYFTGDGATRDKDGYIWIRGRVDDVVNISGHRLSTAEIEAALLSHDAVAESAVVGVHDELTGQAVNAFILLKPGYEATVELEKELIMAVRSTIGPFASPRKLIFSDLPKTRSGKIMRRILRKILAGEVDQIGDLSTLADPKVVEHIIHAVHYAHQKKP
What are the official names of this protein?
Probable acetyl-coenzyme A synthetase, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: KCY_SCHPO
Sequence: MYNVIFVLGGPGAGKGTQCDRLAEKFDKFVHISAGDCLREEQNRPGSKYGNLIKEYIKDGKIVPMEITISLLETKMKECHDKGIDKFLIDGFPREMDQCEGFEKSVCPAKFALYFRCGQETMLKRLIHRGKTSGRSDDNIESIKKRFVTYTKASMPVVEYLKSQNRLITIDAEQDPDAVFEDTVKALQPYL
What is the function of this protein?
Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP.  Plays an important role in de novo pyrimidine nucleotide biosynthesis.  Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP.
What are the official names of this protein?
Uridylate kinase, UK, ATP:UMP phosphotransferase, Deoxycytidylate kinase, CK, dCMP kinase, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic.
Protein: SYP_RHOOB
Sequence: MITRLSHLFLRTLRDDPADAEVPSHKLLVRAGYVRRIAPGVYSWLPLGLRVLREVERVVREEMNGIGAQEISLPALLPREPYEASNRWTEYGEGLFRLKDRKGGDYLLGPTHEELFALTVKGEYNSYKDFPVTLYQVQTKYRDEERPRAGILRGREFVMKDSYSFDLTDEGLTESYRAHRDAYERIFARLGVKYVIVSATSGAMGGSASEEFLAESEIGEDTYVRCLESGYAANVEAVKTLAPEPIPFDGLPAAKVYDTPDTPTIATLVAWANEADLGRTVTAADTLKNLLVKVRQPGGKWELLAIGVPGDREVDDKRLGASLEPAEFELLTEADFEANPFLVKGYVGPKALQANGVRYLVDPRIVDGTSWITGADEKGRHVVGLVAGRDFVPDGTIEAAEVRGGDPSPDGAGELVAARGIEIGHVFQLGRKYTDVFSVDVLGENGKPVRPTMGSYGVGVSRLVAVIAEQHHDDKGLRWPAEVSPADVHVVIANKDDTAREGAEGLAADLDKAGLEVILDDRKASPGVKFKDSELLGVPLVVVVGRGWGEGKVEVRDRFTGESREVAAESALSEIVKTVRG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHAM_BURCH
Sequence: METIAFRMHLHPGKRDEYRRRHDAIWPELADALRAAGISDYWIFLDDDTHHLFAVLKRPADHRIAQLAETDVMRRWWAYMADLMATGPDGRPVEKALEPMFHLE
What is the function of this protein?
Involved in the anomeric conversion of L-rhamnose.
What are the official names of this protein?
L-rhamnose mutarotase, Rhamnose 1-epimerase, Type-3 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose mutarotase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31_PSEA7
Sequence: MKADIHPAYEAIEATCSCGNVIKTRSTLCKPIHLDVCSECHPFYTGKQKVLDTGGRIDRFKQRFGVFGATK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: TX603_LYCSI
Sequence: MKLLLFTALVLVVISLIEVEAENERACIPLEKECTKTPGNCCSGLKCDCYRRFEQGVAKGIQCWCIEKDVTYKGV
What are the official names of this protein?
U6-lycotoxin-Ls1d, Toxin-like structure LSTX-F3.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 06 (U6-Lctx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MURC_AERS4
Sequence: MTKVELAKLRTMIPEMRRVRRIHFIGIGGAGMGGIAEVLANEGYQVTGSDLARNAVTERLASLGAHIFVGHSAEHVSEASVVVVSTAIKQDNPELLAARELRIPVVRRAEMLAELMRFRHGIAIAGTHGKTTTTSLVASIYAEADRDPTFVIGGLLNSAGTNARLGSSRYLIAEADESDASFLHLQPMVSIVTNIEADHMETYGGDFSKLKATFIDFLHNLPFYGLAVVCVDDPVIRGMLPEIARPTITYGLSDDADVQVLDFVQTSNRSCFRVRRKDAGELAVTLNLPGIHNALNAAAAIAVATEDGIGDDAIICALAKFEGVGRRFQQYGEFETGRGKAMLVDDYGHHPSEVKVTINAARTGWPDKRLVMVFQPHRYTRTRDLYEDFSDVLSKVDVLVMLEVYAAGEEPIPGADGRALCRSIRSRGSLEPIFAATPDDVPAILADLIGEGDLVLTQGAGNVGALSRRLGEMKLSIDSMKSGA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHLA2_XENLA
Sequence: MQPGQAVIMEGELEKRSDNLLQFWRKKLCVLTKESLSLFPDAQKKSKCKELKFQSIKKVDCVERTGKYIYFTIVTTDNKEIDFRCLDQSAWNAAITLALIEFQNKAAVQSFRSQQGTNTRVAPCV
What is the function of this protein?
Plays a role in regulating placenta growth.  May act via its PH domain that competes with other PH domain-containing proteins, thereby preventing their binding to membrane lipids (By similarity).
What are the official names of this protein?
Pleckstrin homology-like domain family A member 2, Imprinted in placenta and liver protein.
What is the protein family that this protein belongs to?
Belongs to the PHLDA2 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: YM316_YEAST
Sequence: METNDSDDRIEAIVSEESDELEVNSGTTEETNVLELLTIISGLVVTLVLVVLVVLVVVGVVVLVVLLVVVVLLCDVVVAVVDFEPDEPILIRRYPFLWIPFL
What are the official names of this protein?
Putative uncharacterized membrane protein YMR316C-B.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS4_SINFN
Sequence: MSKRESSKYKIDRRMGENIWGRPKSPVNRREYGPGQHGQRRKSKLSDFGVQLRAKQKLKGYYGDIREKQFRAIFAEASRRKGDTPENLIGLLESRLDAIVYRAKFVPTVFAARQFVNHGHVKVNGVRVNIGSYRCKAGDVIEVKEKSKQLVSVLESVQLAERDVPDYIEADHNKMVATFVRVPALTDVPYPVVMEPHLVVEFYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: YTM1_ASPNC
Sequence: MNGVQDSTSAAASSQSAQRQVRVQLVSKQEDIALPESTGPILVPTGLRRYALSTLVNNLLGNDKPVPFEFLINGAFLRTSIDEYLTANGISAETTLEIEYIRALIPPLHIASFEHDDWVGSVDVLSATSLATSWASAVVSPGQERILSGSYDGLLRVWNMSSQIVATSPSPADGGHGASIKAAKFISPNSIVSAGLDRTVRLWKYNESDDGFSGKITPQIELYGHKSGINSLAVHAPSNRILSASSDHSIGFWSTKKSDAPAAPENLVPSAASRSSKRRKVSSSVSIPQRGPLALLSSHTAPVSAAIFDTNDSTVGYSTSWDHSLRTWDLVTAALVDTRSTSHSLLSLEHLPEHHLLATGTSARHITLIDPRTSATTISAMTLRGHTNAVVSLSRDPHSSYGLISGSHDGTCRIWDIRATKTDNDGVVGESVYSITRRSLEEQGKADAKRVGGEGVKVFSVCWDRSVGIVSAGEDKRIQINRGEGVLSSA
What is the function of this protein?
Component of the NOP7 complex, which is required for maturation of the 25S and 5. 8S ribosomal RNAs and formation of the 60S ribosome.
What are the official names of this protein?
Ribosome biogenesis protein ytm1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR12/YTM1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.