PharMolix/UniProtQA huggingface dataset:
Protein: VITB1_XENLA
Sequence: MRGIILAQLLALAGSEKSQYEPFFSESKPYVYNYEGIILNGIPENGLARSGIKLNCKAEISGYAQRSYMLK
What is the function of this protein?
Precursor of the major egg-yolk proteins that are sources of nutrients during early development of oviparous organisms.
What are the official names of this protein?
Vitellogenin-B1, VTG B1.
Protein: RFAQ_ECOLX
Sequence: MRFHGDMLLTTPVISSLKKNYPDAKIDVLLYQDTIPILSENPEINALYGIKNKKAKASEKIANFFHLIKVLRANKYDLIVNLTDQWMVAILVRLLNARVKISQDYHHRQSAFWRKSFTHLVPLQGGNVVESNLSVLTPLGVDSLVKQTTMSYPPASWKRMRRELDHAGVGQNYVVIQPTARQIFKCWDNAKFSAVIDALHARGYEVVLTSGPDKDDLACVNEIAQGCQTPPVTALAGKVTFPELGALIDHAQLFIGVDSAPAHIAAAVNTPLISLFGATDHIFWRPWSNNMIQFWAGDYREMPTRDQRDRNEMYLSVIPAADVIAAVDKLLPSSTTGTSL
What is the function of this protein?
Catalyzes heptose transfer to the lipopolysaccharide core.  It transfers a heptose, called heptose(III), to the heptose(II) of the inner core.
What are the official names of this protein?
Lipopolysaccharide core heptosyltransferase RfaQ.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 9 family.
Protein: RS14Z_BACC4
Sequence: MAKKSMIAKQKRTPKFKVQEYTRCERCGRPHSVYRKFKLCRICFRELAYKGQIPGVKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: EFTU_CHACO
Sequence: MAQEVFQRTKPHVNIGTIGHVDHGKTTLTAAITMTLAVNSTCTPKKYDEIDAAPEERARGITINTAHVEYETALRHYAHVDCPGHADYIKNMITGAAQMDGAILVVSAADGPMPQTKEHILLAKQVGVPSIVVFLNKEDQVDDEEILQLVDLEVRESLINYEFPGDKVPVVSGSALMALQALTEKPNTSRGENKWVDKIYELMDAVDSYIPTPKRDIEKPFLMPIEDVFSIQGRGTVATGRIERGILKLGDIVELIGLNEKIRSTVVTGLEMFRRLLEQGFAGENIGVLLRGIEKKDIERGMVIAQPGTIEPHTRFEAQVYILRKEEGGRHSPFFAGYRPQFFVRTADVTGVIEAFEYDNGDKTRMVMPGDRVKMIVNLICPIAIEKKMRFAIREGGRTIGAGVVYKY
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, chloroplastic, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MMP20_BOVIN
Sequence: MLPASGLAVLLVTALKFSTAAPSLPAASPRTSRNNYRLAQAYLDKYYTKKGGPQIGEMVARGGNSTVKKIKELQEFFGLRVTGKLDRATMDVIKRPRCGVPDVANYRLFPGEPKWKKNTLTYRISKYTPSMTPAEVDRAMEMALRAWSSAVPLNFVRINAGEADIMISFETGDHGDSYPFDGPRGTLAHAFAPGEGLGGDTHFDNAEKWTMGTNGFNLFTVAAHEFGHALGLAHSTDPSALMFPTYKYQNPYGFRLPKDDVKGIQALYGPRRAFSGKPTAPHGPPHNPSIPDLCDSNLSFDAVTMLGKELLLFRDRIFWRRQVHLMSGIRPSTITSSFPQLMSNVDAAYEVAERGTAYFFKGPHYWITRGFQMQGPPRTIYDFGFPRYVQRIDAAVYLKDAQKTLFFVGDEYYSYDERKRKMEKDYPKSTEEEFSGVNGQIDAAVELNGYIYFFSGPKAYKSDTEKEDVVSELKSSSWIGC
What is the function of this protein?
Degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterizing the cartilage extracellular matrix: aggrecan and the cartilage oligomeric matrix protein (COMP).  May play a central role in tooth enamel formation.  Cleaves aggrecan at the '360-Ser-|-Phe-361' site.
What are the official names of this protein?
Matrix metalloproteinase-20, MMP-20, Enamel metalloproteinase, Enamelysin.
What is the protein family that this protein belongs to?
Belongs to the peptidase M10A family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: YP2B_STAAU
Sequence: MALQSRNSDENEKKNENTMNMQTRSKLTGTHSQKIQKTLENEELQELKKQNKLVIKYISEMKEQQDLREKELQAIKSSLKKTTEDFQGRGKKVHNDFVRLLQKNLNRVNAEDIEIEVRKDVYGVREEIHSMLREVKQSHEHYQKRQKQLFTGIGAMLLVFMLFALIMTIGRDFMGFLHVDVLQNAIASKIKASEGFISVLWYIAYGLPYILAIGLFIWLYEWIRARFHD
What are the official names of this protein?
Uncharacterized protein ORFD.
Protein: DNPEP_DICDI
Sequence: MEQYLPQAKEFISFIDKSPSPYHAVQYFSEILKSKGFIHLSEKQMWDIQPNKKYFFTRNQSCISAFAVGGKYKPGNGFNIAAAHTDSPNFKVRPVSKVESVGYQQVGVETYGGGLWYTWFDRDLTVAGRVIVKSGDGSYESKLVHIKKPILRIPSLAIHLDRSVNTDGFKYNTQNHLVPMIASKLSEPVESKSTTTTTTTESPKTSDPQDVNSSTTKHHAVLLELLSKELGCSVGDIQNFDLSVCDTQPAAIGGALDEFIFSPRCDNLGMSYCAMIGLLNVKESTLAQEENVLNVILFDNEEVGSSSPQGACAPLINDTISRVNSSMFASTCKPHELNNFIDLTLRNSFLISADMAHAIHPNYTANHEPLHRPALNKGPVIKYNANLRYASNGPTSFVILDICKKNGIPIQEFLVKNDSPCGSTIGPIISGTYGIRTVDIGNPQLSMHSIRETCGVADITHGINLIQKYFEQFTKLDIIKSDLE
What is the function of this protein?
Likely to play an important role in intracellular protein and peptide metabolism.
What are the official names of this protein?
Aspartyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M18 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARAG_RHIEC
Sequence: MAFLEFNNVSKGYPGVQALANVSFTVEKGVVHGLMGENGAGKSTLIRVLSGDQAADGGNIFIDGEEQKYTSVRDAFHAGIVVIHQELQLVPELTVAENLWLGRFPAKGGIIHLKTLIETVRAKLEEIGIDVDPSTKVSSLSIGARQMIEIAKAVMLDARVIALDEPTSSLSSRESEILFSLIARLKARGAVILYVSHRLDEIFRLCDSLTVLRDGKLAAHHPKIAETTREQIISEMVGREISNVWGWRERALGDNRLEVKGLSGPRLHTPISFSVRQGEILGFFGLIGAGRSEMARLLYGADARHRGEVTIDGVAVSPNNPKVAIKAGMVLCPEDRKFDGIVQGRSIEENIAISSRRHFSRFGILKPKTEAAQADRFIAKLRVRTPSRRQDIVNLSGGNQQKVILGRWLSEQGIKVLVIDEPTRGIDVGAKSEIYDILYELAAGGVAIVVISSELPEVMGICDRIIVMCQGRVAANVARPDFDERSILTAALPDKNAAGSI
What is the function of this protein?
Part of the ABC transporter complex AraFGH involved in arabinose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Arabinose import ATP-binding protein AraG.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Arabinose importer (TC 3.A.1.2.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y803_METJA
Sequence: MNSYGVILISYVGLIKLALAGILCYGIYLAIKSEKNLIKDALFVYKDNNFNVFGKKYALMIFLAFGFPIFFIGSFLYLFWEKLPEGFRFSLTFAITFFVLFIFGLLFVKYKIRVCKNGIYVGFRFITWKGFEGYKIENNKIILIGKKGVTYPVHLKYSKELEDIIKNYLKKI
What are the official names of this protein?
Uncharacterized protein MJ0803.
What is the protein family that this protein belongs to?
To M.jannaschii MJ0695.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SCX10_TITPA
Sequence: KDGYLVGNDGCKYSCLTRPGHYCASECSRVKGKDGYCYAWMACYCYNMPNWVKTWSRATNKCGKRK
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
What are the official names of this protein?
Toxin Tppa2, Toxin Cocle-A1.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PR20D_HUMAN
Sequence: MEEPRPSKRLRSMAPNQASGGPPPEPGCCVADPEGSVEADGPAQPAQPAKPIAYVKPFRRQPPARPESPPPAERGRRRGGSRRPGRGRGRRAGPRGDAGQRQGAEGLMAPDVHIQLDHHGEPGHQGEPEITETAAFSLSETGPPPGTVQEGPGPDVAQPELGFQEPPAAPGPQAVDWQPVLTLYPCIGFRALGDSAVLQVIQTPQGTYVQGVPVFLTDIAY
What are the official names of this protein?
Proline-rich protein 20D.
What is the protein family that this protein belongs to?
Belongs to the PRR20 family.
Protein: SMG_SODGM
Sequence: MFDVLMYLFETYIHNEVEMRVDQDKLTDDLTQAGFHQDDIYNALNWLEKLADLQDGTGRAFALNADPLAMRIYTDEESQFLDTDCRGFLLFLEQIQVLNLETREMVIDRVMALDAAEFDLEDLKWVILMVLFNIPGCENAYQQMEDLVFEEDEQHLH
What are the official names of this protein?
Protein Smg.
What is the protein family that this protein belongs to?
Belongs to the Smg family.
Protein: DUS15_RAT
Sequence: MGNGMTKVLPGLYLGNFIDAKDPDQLGRNKITHIVSIHESPQPLLQDITYLRISVSDTPEVPIKKHFKECVHFIHSCRLNGGNCLVHCFAGISRSTTVVIAYVMTVTGLGWQEVLEAIKASRPIANPNPGFRQQLEEFGWANSQKLRRQLEERFGEIPFRDEEDLRALLPLCRRCRQGPGTSAPSATTASSAASEGTLQRLVPRSPRESHRPLPLLARVKQTFFCLPRCLSRKGGK
What is the function of this protein?
May play a role in the regulation of oligodendrocyte differentiation.  May play a role in the regulation of myelin formation (PubMed:27532821).  Involved in the regulation of Erk1/2 phosphorylation in Schwann cells; the signaling may be linked to the regulation of myelination (PubMed:27891578).  May dephosphorylate MAPK13, ATF2, ERBB3, PDGFRB and SNX6 (By similarity).
What are the official names of this protein?
Dual specificity protein phosphatase 15.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: XYLA_STRS8
Sequence: RHAGSAHTF
What is the function of this protein?
Involved in D-xylose catabolism.
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE1_STAAW
Sequence: MSFKMTQNQYTSLYGPTVGDSIRLGDTNLFAQIEKDYAVYGEEATFGGGKSIRDGMAQNPRVTRDDVNVADLVISNAVIIDYDKVVKADIGIKNGYIFAIGNAGNPDIMDNVDIIIGSTTDIIAAEGKIVTAGGIDTHVHFINPEQAEVALESGITTHIGGGTGASEGSKATTVTPGPWHIHRMLEAAEGLPINVGFTGKGQATNPTALIEQINAGAIGLKVHEDWGATPSALSHALDVADEFDVQIALHADTLNEAGFMEDTMAAVKDRVLHMYHTEGAGGGHAPDLIKSAAFSNILPSSTNPTLPYTHNTVDEHLDMVMITHHLNAAIPEDIAFADSRIRKETIAAEDVLQDMGVFSMISSDSQAMGRVGEVITRTWQVAHRMKEQRGPLDGDFEHNDNNRIKRYIAKYTINPAITHGISEYVGSIEPGKLADIVLWDPIFFGVKPELVVKGGLINSAVNGDANGSIPTSEPMKYRKMYGQYGGNLTSTSMTFVSKTAYENGINRALNLKRMVRPVKNIRQLSKADMKNNSATPKLDVDPQTYEVYVDGEKITSNAATELPLTQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABZ_BURM9
Sequence: MSTEKINFDIHKILTLLPHRYPILLVDRVLELEPHKAIKALKNVTVNEPFFTGHFPKRPVMPGVLIIEALAQAAALLTFAEAQPKDPENTLYYFVGIDNARFKRVVEPGDQLILNVTFERYIRGIWKFKAVAEVDGKVAAEAELMCTVKTADAAP
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_MYCGE
Sequence: MLILVNNPKAKYDYHLMESYCAGIVLKGSEVKALSLGQGSLKEAYVFVKNNELFLEQFTIPPYSFAGPLNHASDRIKKLLLNKHEIKQIINKKQQQSLSVIPSKVFFRNGKIKVEIWLAKPKKKFDKRETIKKKTIRRELEAEYR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: RT106_VANPO
Sequence: MTDSFLDKLPAGLKSKVSTIIRALPSSKSVFQELYEFALNENDDSKRKMSKNSPSDICASLEPVHEEFTIFKIEDVTILSPIRKKLNLVLHISPTTKKPLLSLTNKDGGQELTIEDLNKNISMATFLPVPEKKNIFYMFINYKESVGSKYTEPVLITINKTNILEQFKKVGLIDLEIQDFTKCIEYIRKQAILTGFRMSDPFFSVRQDSDSVPSFHVEGHRGTKEGTLYFLPDHIIFGFKKPILLFQSIDIESITYSSITRLTFNVTLITKNDEKFEFSMIDQTEYSKIDEYVKMRQVKDRSMSEELKAKTANKNQQSQNEDDEQISALEAAAQQMEKNMNINDIPVDSDDEEDDGNFEAESDLSDGSDVEAEDDYAEDDEDDEDEEDEEDKEDEENDRFEHNEDQYEEKEASLLDIEHGDSVNYDDPGQDGFSVDLGIDDVPIELDEDDEEGSGVEYD
What is the function of this protein?
Histones H3 and H4 chaperone involved in the nucleosome formation and heterochromatin silencing.  Required for the deposition of H3K56ac-carrying H3-H4 complex onto newly-replicated DNA.  Plays a role in the transcriptional regulation of the cell-cycle dependent histone genes by creating a repressive structure at the core histone gene promoter (By similarity).
What are the official names of this protein?
Histone chaperone RTT106.
What is the protein family that this protein belongs to?
Belongs to the RTT106 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: HDHD1_HUMAN
Sequence: MAAPPQPVTHLIFDMDGLLLDTERLYSVVFQEICNRYDKKYSWDVKSLVMGKKALEAAQIIIDVLQLPMSKEELVEESQTKLKEVFPTAALMPGAEKLIIHLRKHGIPFALATSSGSASFDMKTSRHKEFFSLFSHIVLGDDPEVQHGKPDPDIFLACAKRFSPPPAMEKCLVFEDAPNGVEAALAAGMQVVMVPDGNLSRDLTTKATLVLNSLQDFQPELFGLPSYE
What is the function of this protein?
Dephosphorylates pseudouridine 5'-phosphate, a potential intermediate in rRNA degradation.  Pseudouridine is then excreted intact in urine.
What are the official names of this protein?
Pseudouridine-5'-phosphatase, Haloacid dehalogenase-like hydrolase domain-containing protein 1, Haloacid dehalogenase-like hydrolase domain-containing protein 1A, Protein GS1, Pseudouridine-5'-monophosphatase, 5'-PsiMPase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
Protein: SSTT_ACTSZ
Sequence: MNTSRFISLFFHGSLVKRIIVGLVLGVVTALISPDLEPVLGFNLAEKVGILGSLFVKGLRAVAPILIFVLVIAAIANKKVGSKSNMKDIVMLYIIGTFGASIVAVLASFSFPMYIPLTTVADSLTPPNSVSEVFVVVISNIFANPIEALATSNFIGILAWAIALGIALRHAAQATKNAVNDLAEAVSKIVHLVISLAPFGIFGLVAATLADKGLGALWDYAHLLLVLLGSMLFMALVVNPFIVYWKIRRNPYPLVWKCISVSGLTAFFTRSSAANIPVNIDLAEELGLDEETYSVSIPLGATINMAGAAITVTVLTLAAVQTLGIPVSIPTAILLSVVSAVCACGASGVAGGSLLLIPLACSLFGISGDVAAQVIAVGFVIGVLQDSTETALNSSTDVLFTAAVCMAEERKNNA
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL35_GLOC7
Sequence: MPKLKTRKAAAKRFRATGSGNKIFRRKAYKNHLLYHKSAERKRRRLSGLALVSEEDIKEVRLMLPYL
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: RECF_LACP3
Sequence: MKLDHLVLKNYRNYAAVDTTFSPEINVLIGANAQGKTNLLESIYVLALARSHRTNNDKELIRFGSEFARVSGQVSRQSGSHQLELIISHQGKRARIDRIEQPKLSQYLGHFNVILFAPEDLAIVKGSPAGRRRFIDMEFGQMSPKYLYNLSQYKTFLKQRNAYLKQLKYHQAKDLVYLDVLTDSLAAFGAELITARAKLLETMSDYAATIQQDITKGRESLHFSYQTQVDPSLRGNSEQVYTALGEMFAKQQAREIEQGTSLVGPQRDDVLFIVNDKDVANFGSQGQQRTTALAVKLAEIDLMKDQTGEYPVLLLDDVLSELDAARQTHLLKAIQTKVQTFLTTTSLEGIQKEIIATPAVFKVDEGTLARA
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMHL_STAAR
Sequence: MEDTVIVGRHAVREAIITGHPINKILIQEGIKKQQINEILKNAKDQKIIVQTVPKSKLDFLANAPHQGVAALIAPYEYADFDQFLKQQKEKEGLSTVLILDGLEDPHNLGSILRTADATGVDGVIIPKRRSVTLTQTVAKASTGAIEHVPVIRVTNLAKTIDELKDNGFWVAGTEANNATDYRNLEADMSLAIVIGSEGQGMSRLVSDKCDFYIKIPMVGHVNSLNASVAASLMMYEVFRKRHDVGEI
What are the official names of this protein?
Putative TrmH family tRNA/rRNA methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
Protein: DNAJ_TRIEI
Sequence: MARDYYEILGVSRSADKEELKRAYRRLARKYHPDVNKEPGSEERFKEINRAYEILSDPEMKARFDRFGEAGVSGGAASGFSTDFSDSFADIFESFFSGFGGAGTQGRRRTGPVRGDDLRLDLNLEFIEAIFGGDKELTIKHLETCGTCNGSGAKPGTKPQTCSTCGGTGQVRRATRTPFSSFTQVSVCPSCNGSGQIIEEKCVDCGGRGQKEATKKIKITIPGGVDNGTRLRVSNEGDAGRMGGPPGDLYVFLSVKNHPEFQRDGINIISQIKISYLQAILGCCLEINTVDGKTELTIPSGTQPNAILTLEDKGVPRLGNSVSRGAHLITIEIDIPTKITPEEKELLEKLAKIKGERTGKGGIEGFLGSWFQQK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y607_METJA
Sequence: MHYSIIKPKCKKEIIEIDKGSLKTKRKFAFLLEIGDKILNNKEFYANDDVEVVVDYSFTDSKRPKEKIELYIIEDIKRD
What are the official names of this protein?
Uncharacterized protein MJ0607.
Protein: MIP_LITPI
Sequence: MWEFRSFSFWRAVFAEFFGTMFYVFFGLGASLKWAAGPANVLVIALAFGLVLATMVQSIGHVSGAHINPAVTFAFLIGSQMSLFRAIFYIAAQLLGAVAGAAVLYGVTPAAIRGNLALNTLHPGVSLGQATTVEIFLTLQFVLCIFATYDERRNGRLGSVSLAIGFSLTLGHLFGLYYTGASMNPARSFAPAVLTRNFTNHWVYWVGPIIGGALGGLVYDFILFPRMRGLSERLSILKGARPAEPEGQQEATGEPIELKTQSL
What is the function of this protein?
Water channel.  May be responsible for regulating the osmolarity of the lens.  Interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core.
What are the official names of this protein?
Lens fiber major intrinsic protein, MIP26, MP26.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Protein: RL11_RICCK
Sequence: MSQKAIKGYINLIIPAAGATPAPPIGPALGQRKVNIAAFCKDFNDATQAMEKGIPLPTVITVYEDRSFSFKIKTSPASYFLKKYAKITKGSSATKKEAVVGKVTMDDCREIAKLKMPDLNTKNIEAATKIICGSAASMGLEVVGN
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: YIDC_BUCMP
Sequence: SRTLIKSKLWVGPEIQKEMKLVAPNLDLTVDYGWLWFLSQPLFKLLTIINSIINNWGFSIILITFIMKIITYPLTKSQYVSMSKIRALQPKIKEIKEAFSDNKQRISQEMIILYKKEKINPLGGFLPVFIQMPVFLSLYYMLIGSVELRHAPFVLWIKDLSSQDPFYVLPIIMGLTMFFIQKTSSNNISDPIQKKIMNFMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQKFIFSNFKSN
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins (By similarity).
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AI7_USTMA
Sequence: MVRWLYSTNAKDIGTLYLIFAVFAAMIGTAFSVLIRMELAAPGVQYLNGDHQLYNVIITAHAFVMIFFMVMPAMVGGFGNYLVPVMIGAPDMAFPRLNNISFWLLPPSLILLLASAFVEQGAGTGWTVYPPLSGLQSHSGGSVDLAIFSLHLSGISSMLGAMNFITTVLNMRNPGMTLHKLPLFVWAIFVTAILLLLSLPVLAGAITMLLTDRNFNTSFYDPAGGGDPILYQHLFWFFGHPEVYILIIPGFGMVSHIVSAFSGKPVFGYLGMVYAMFSIGILGFLVWSHHMYAVGLDVDTRAYFTAATMIIAVPTGIKIFSWLKGSFSKTFLANSINVLSEAVLTLRERFPRANLYPKNCLINNECIDLVPYGYYLTGTMHYPRYNIILQHMVSLTSYLYGVVVGLMLSDAWMNKKNMNGQARLFLKQSINNAFYLFYTFSLLSHYCSSYPYIVNSRGFIAVAFVTRTLTCFTELYNNFYENGKKCVPSDIYNMLTIQGLSHWICGDGTFVKGGGIYLQAQSFTVIEVVHLINVLIIKFNCKCTIHYQEGKPVIYISSRSVRKLRTELLKHMPMHYKLTGKTSRVN
What is the function of this protein?
Mitochondrial DNA endonuclease involved in intron homing.
What are the official names of this protein?
Probable intron-encoded endonuclease aI7.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion. Membrane; Multi-pass membrane protein.
Protein: RS3_ELMPH
Sequence: MGQKSNPNGLRLGIIRTWESKWYDVDKKVPFLVGEDFKIRTLIKNHYPKSTISQIEIKRLKKSNDEFIEIDLYTSKIGIIQGPENKNKNSLINKIEKLINKKIQINIFEVKAFNKIAILVAQNIAMQLQQRAFYKAVLKSAIQKALKSGIKGIKIIITGRLGGAEKARRNSISMGIVPLNTLRADIDYAFEEAHTTYGVLGVKVIINHGEVLPNKTIADTRQIFSSQYENKKNNNKRHFVNKKNFKTSTS
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: GLMU_RHIL3
Sequence: MERTCLAVILAAGDSTRMKSSKSKVLHPVAGRPMIAHVVEAVASAGISSVALVVGRDAEDVAKAASIAGVDIESFLQKERLGTGHAVLAAREAIAKGYDDILVTYGDVPLQTDGPLKAARQGLADGSDVVVIGFHTDRPTGYGRLLVKDGELIAIREEKDATDAERTVTWCNSGLMAINGRKALDLLSRIGNANAKGEFYLTDLVEIARSLGGRVTAVDAPEIEMTGCNTRAELAVIERFWQERRRHQMMLSGVTMIAPETVFLAYDTVIGQDALIEPNVVFGPGAVIDSGAVIHAFSHIEGAHVSQGATVGPFARLRPGADLGTGSKVGNFCEVKNGRLGEGAKVNHLTYIGDAVIGAGSNIGAGTITCNYDGVNKSETVIGENAFIGSNSSLVAPVTIGDGAYIASGSVITVNVPADALALGRARQEIKTGRATLLRERALAIKAAKKAKA
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.