PharMolix/UniProtQA huggingface dataset:
Protein: KI16B_HUMAN
Sequence: MASVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSFYSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDSGLIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPKEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFDSEMPCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDAANTLAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNIINKPTINEDANVKLIRELRAEIARLKTLLAQGNQIALLDSPTALSMEEKLQQNEARVQELTKEWTNKWNETQNILKEQTLALRKEGIGVVLDSELPHLIGIDDDLLSTGIILYHLKEGQTYVGRDDASTEQDIVLHGLDLESEHCIFENIGGTVTLIPLSGSQCSVNGVQIVEATHLNQGAVILLGRTNMFRFNHPKEAAKLREKRKSGLLSSFSLSMTDLSKSRENLSAVMLYNPGLEFERQQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEESLKRRSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRLKELNNNEKAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQLLRRGEVQWVEEEKRDLEGIRESLLRVKEARAGGDEDGEELEKAQLRFFEFKRRQLVKLVNLEKDLVQQKDILKKEVQEEQEILECLKCEHDKESRLLEKHDESVTDVTEVPQDFEKIKPVEYRLQYKERQLQYLLQNHLPTLLEEKQRAFEILDRGPLSLDNTLYQVEKEMEEKEEQLAQYQANANQLQKLQATFEFTANIARQEEKVRKKEKEILESREKQQREALERALARLERRHSALQRHSTLGMEIEEQRQKLASLNSGSREQSGLQASLEAEQEALEKDQERLEYEIQQLKQKIYEVDGVQKDHHGTLEGKVASSSLPVSAEKSHLVPLMDARINAYIEEEVQRRLQDLHRVISEGCSTSADTMKDNEKLHNGTIQRKLKYERMVSRSLGANPDDLKDPIKISIPRYVLCGQGKDAHFEFEVKITVLDETWTVFRRYSRFREMHKTLKLKYAELAALEFPPKKLFGNKDERVIAERRSHLEKYLRDFFSVMLQSATSPLHINKVGLTLSKHTICEFSPFFKKGVFDYSSHGTG
What is the function of this protein?
Plus end-directed microtubule-dependent motor protein involved in endosome transport and receptor recycling and degradation.  Regulates the plus end motility of early endosomes and the balance between recycling and degradation of receptors such as EGF receptor (EGFR) and FGF receptor (FGFR).  Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development.
What are the official names of this protein?
Kinesin-like protein KIF16B, Sorting nexin-23.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Early endosome membrane. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Note=It is unclear whether association with endosomes is mediated via phosphatidylinositol 3-phosphate (PtdIns(3)P)-binding or via its interaction with RAB14.
Protein: TRM6_HUMAN
Sequence: MEGSGEQPGPQPQHPGDHRIRDGDFVVLKREDVFKAVQVQRRKKVTFEKQWFYLDNVIGHSYGTAFEVTSGGSLQPKKKREEPTAETKEAGTDNRNIVDDGKSQKLTQDDIKALKDKGIKGEEIVQQLIENSTTFRDKTEFAQDKYIKKKKKKYEAIITVVKPSTRILSIMYYAREPGKINHMRYDTLAQMLTLGNIRAGNKMIVMETCAGLVLGAMMERMGGFGSIIQLYPGGGPVRAATACFGFPKSFLSGLYEFPLNKVDSLLHGTFSAKMLSSEPKDSALVEESNGTLEEKQASEQENEDSMAEAPESNHPEDQETMETISQDPEHKGPKERGSKKDYIQEKQRRQEEQRKRHLEAAALLSERNADGLIVASRFHPTPLLLSLLDFVAPSRPFVVYCQYKEPLLECYTKLRERGGVINLRLSETWLRNYQVLPDRSHPKLLMSGGGGYLLSGFTVAMDNLKADTSLKSNASTLESHETEEPAAKKRKCPESDS
What is the function of this protein?
Substrate-binding subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA (PubMed:16043508).  Together with the TRMT61A catalytic subunit, part of a mRNA N(1)-methyltransferase complex that mediates methylation of adenosine residues at the N(1) position of a small subset of mRNAs: N(1) methylation takes place in tRNA T-loop-like structures of mRNAs and is only present at low stoichiometries (PubMed:29107537, PubMed:29072297).
What are the official names of this protein?
tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6, mRNA methyladenosine-N(1)-methyltransferase non-catalytic subunit TRM6, tRNA(m1A58)-methyltransferase subunit TRM6, tRNA(m1A58)MTase subunit TRM6.
What is the protein family that this protein belongs to?
Belongs to the TRM6/GCD10 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RLMN_SHESR
Sequence: MSEKKINLLDLDRKAMRALFADLGEKPFRADQLMKWIYHFGVSDFEEMTNINKVLRQKLAARCEIVAPEISSYQKSTDGTIKFAIHVGEGQEVETVYIPEDDRATLCVSSQVGCALECTFCSTAQQGFNRNLTVSEIVGQIWRVSHFLGFAKDTGERPITNVVMMGMGEPLLNLANVIPAMDIMLDDFGFSLSKRRVTLSTSGVVPALDKLGDALDVALAVSIHAPNDELRDILVPVNKKYPLQEFLAGIRRYIAKSNANRGRVTVEYVMLDHINDSTEQAHELAQLMKDTPCKVNLIPFNPYPGSPYGRSSNSRIDRFSKVLMEYGLTVIVRKTRGDDIDAACGQLAGDIRDRTKRLAKKRMQENQISVTMN
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_CLOK5
Sequence: MNEVIQTTVAGRTLKVDCEKVGMLSNCGMLISYGDTVVLINANASDKPREGIDFFPLSIEYEERLYSVGKIPGGFIKREGKPSEKAILNARAIDRPLRPLFPKGYRNDVQVVCTVLSVDQDNLPNIVAMNGASLALCISSIPFITPVGSVAVGLVDGNFIINPNLEDREKSTLNLTVCATKERVMMVEAGACEVPEDIMYDAIIFGFEECKKIALFQEEVMKKYGKKKDEPDLYKVNEDLEEEVRGFAFDMIKDAMYIVDRDERNKVLKDIDEKLEEQFSEDYADNKSDIADVVYRVKKEIVRGMLLKEHRRVDGREFDEVRPISCEVGFLPRAHGTGLFTRGLTQVMTVVTLGSLGDVQILDGVGLEDSKRYMHHYNFPSYSTGEVRPLRGPGRREIGHGALAEKALEPLIPMEEQFPYTIRLVSEVLSSNGSTSQASICGSTLALLDAGVPIKRPAAGIAMGLVTSEDLSQEEILTDIQGLEDFFGDMDFKVGGTEKGITAIQFDTKIHGLSNKCIKETLEKARTARLYILEKMKQCIPEHRAEVSKYAPKTYIMSIPPDKIRDVIGSGGKVINKIIAETGVKIDIKEDGKIFVMSEDSEGAKKALKIIDDLTREILVGEIYLGKVTKITNFGAFVEIHKGKEGLVHISKLDFTRVNKVEDIVSVGDEILVKVIEIDNQGRINLSRKDAIKDSEKKEQNEKDVQKK
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DADA_AERHH
Sequence: MDIVVLGGGVVGVTSAWYLAKAGHKVTLLERRDGVALETSHANAGQISPGYAAPWAAPGIPLKAAKWLLQKHAPFTVRPTSDPFQLRWMLKMFANCTPAAYAVNKGRMVRLAEYSRDCMKLLRDELSIDYEGRQLGTLQLFRSQAQLDASKRDIEVLEEYGVPYQSLDAAGCEGAEPALARVRGKIVGGLRLPGDETGDCFRFTKAMAAEAQRLGVKFVFNCAIDEIELAQGRAVAVRAGEQRFKADAIVCALGSYATGFLRPLGLDLPVYPVKGYSLTLPMINAEASPRSTVLDETYKVAITRFDERIRVGGMAELSGYNLALNPKRHDTLAMVVGDLFPEGGDISRADFWTGLRPMTPDGTPLVGPSPIPGLWLNTGHGTLGWTMAAGSGQLLCDLISGSDTAISDEGLTLARYG
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: ZFP2_HUMAN
Sequence: MEREGIWHSTLGETWEPNNWLEGQQDSHLSQVGVTHKETFTEMRVCGGNEFERCSSQDSILDTQQSIPMVKRPHNCNSHGEDATQNSELIKTQRMFVGKKIYECNQCSKTFSQSSSLLKHQRIHTGEKPYKCNVCGKHFIERSSLTVHQRIHTGEKPYKCNECGKAFSQSMNLTVHQRTHTGEKPYQCKECGKAFHKNSSLIQHERIHTGEKPYKCNECGKAFTQSMNLTVHQRTHTGEKPYECNECGKAFSQSMHLIVHQRSHTGEKPYECSQCGKAFSKSSTLTLHQRNHTGEKPYKCNKCGKSFSQSTYLIEHQRLHSGVKPFECNECGKAFSKNSSLTQHRRIHTGEKPYECMVCGKHFTGRSSLTVHQVIHTGEKPYECNECGKAFSQSAYLIEHQRIHTGEKPYECDQCGKAFIKNSSLTVHQRTHTGEKPYQCNECGKAFSRSTNLTRHQRTHT
What is the function of this protein?
Probable transcription factor involved in neuronal differentiation and/or phenotypic maintenance.
What are the official names of this protein?
Zinc finger protein ZFP2, Zfp-2, Zinc finger protein 751.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TPIS_HAES1
Sequence: MARRPLVMGNWKLNGSKAFTKELITGLKDELNAVSGCDVAIAPPVMYLAEAETALVSSDIALGTQNVDLNKQGAFTGDISTEMLKDFGVKYVIIGHSERRQYHHESDEFIAKKFGVLKDAGLVPVLCIGESEAENEAGKTEEVCARQIDAVMNTLGVEAFNGAVIAYEPIWAIGTGKSATPAQAQAVHAFIRGHIAKQSQAVAERVIIQYGGSVNDANAAELFTQPDIDGALVGGASLKASAFAVIVKAAAKAKN
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTC_STRPG
Sequence: MTQVFQGRSFLAEKDFTRAELEYLIDFSAHLKDLKKRGVPHHYLEGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMFDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVKENFGKLEGLTLVYCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEEEIVTLAEGYAKESGARILITEDADEAVKGADVLYTDVWVSMGEEDKFKERVELLQPYQVNMDLVQKAGNDKLIFLHCLPAFHDTNTVYGKDVAEKFGVKEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLFIPKV
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GH_EBVG
Sequence: MQLLCVFCLVLLWEVGAASLSEVKLHLDIEGHASHYTIPWTELMAKVPGLSPEALWREANVTEDLASMLNRYKLIYKTSGTLGIALAEPVDIPAVSEGSMQVDASKVHPGVISGLNSPACMLSAPLEKQLFYYIGTMLPNTRPHSYVFYQLRCHLSYVALSINGDKFQYTGAMTSKFLMGTYKRVTEKGDEHVLSLIFGKTKDLPDLRGPFSYPSLTSAQSGDYSLVIVTTFVHYANFHNYFVPNLKDMFSRAVTMTAASYARYVLQKLVLLEMKGGCREPELDTETLTTMFEVSVAFFKVGHAVGETGNGCVDLRWLAKSFFELTVLKDIIGICYGATVKGMQSYGLERLAAMLMATVKMEELGHLTTEKQEYALRLATVGYPKAGVYSGLIGGATSVLLSAYNRHPLFQPLHTVMRETLFIGSHVVLRELRLNVTTQGPNLALYQLLSTALCSALEIGEVLRGLALGTESGLFSPCYLSLRFDLTRDKLLSMAPQEAMLDQAAVSNAVDGFLGRLSLEREDRDAWHLPAYKCVDRLDKVLMIIPLINVTFIISSDREVRGSALYEASTTYLSSSLFLSPVIMNKCSQGAVAGEPRQIPKIQNFTRTQKSCIFCGFALLSYDEKEGLETTTYITSQEVQNSILSSNYFDFDNLHVHYLLLTTNGTVMEIAGLYEERAHVVLAIILYFIAFALGIFLVHKIVMFFL
What is the function of this protein?
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell.  Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL.  May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis.  The heterodimer gH/gL targets also host EPHA2 to promote viral entry.
What are the official names of this protein?
Envelope glycoprotein H, gH.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein H family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN).
Protein: RECO_SYNPW
Sequence: MSGDRRLQGLALKVGPLGEHDRLLTLLSDDVGVVRLAVPGARRPRSSLAAAVPLTCLDLQVVGRRGLARVRQLRVLRSYSGLGQRLDTLASAQALAELAIALVSSDDPVPGLLEAVLIHLDRLERLSRTPGEEADLCLANVVQAGVHLLALGGYGLPLQACCRSGAALTPPIGQWEWRCSVLPEEGLALGALAGARLQLNPSELALLQRLPRPDLPRRSNGELLGPRPVWLKLLALLECWCRAHLPRPVRSLAMVRDCLSAAPLSDHEPT
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: PLAS_VICFA
Sequence: VEVLLGASDGGLAFVPNSFEVSAGDTIVFKNNAGFPHNVVFDEDEIPSGVDAAKISMPEEDLLNAPGETYSVKLDAKGTYKFYCSPHQGAGMVGQVTVN
What is the function of this protein?
Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I.
What are the official names of this protein?
Plastocyanin.
What is the protein family that this protein belongs to?
Belongs to the plastocyanin family.
Protein: YQGU_BACSU
Sequence: MLMRSVCFILLAVLLFSLSACEPSHQQQKQASAAKDEKKDIIPLSAEKADGAEGWLNNSTILYTASNPTKTELFAYRIFTGKAKKLYQTDGQIVDVQINAREQMILLQITHSQKTAVVLLNAEGETLYEKDYETYELEAAWNQYDPYQMMVTEFNENWDFHTYQVNAKKDESFLSPVQVPFIHWTSKNTFDYVKEGRDDKTGPLYTFDTASKTEQKLEDNVLFFDSFHQMSFTVKSASGGKGTYQFKTPQSTSPVTAKWPLQAKYTSLAPMEYDYDEAGGLFYTFKQSGDAYKLAAINVASGETKDLVSLREMEPIQISPNGKYALYGFHFEQIILLKSHETKQLIIDQKEME
What are the official names of this protein?
Uncharacterized lipoprotein YqgU.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: ACYP_PSYIN
Sequence: MDNIGCKVIVSGIVQAVGFRYFTCREARLHYVMGHAKNLQCGDVEVVMYGPREQIAKMLKWLEKGPKTARVTGITVSEIPYQKTNDFIAC
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: SYP_FLAPJ
Sequence: MSKNLTTRAEDYSKWYNELVVRADLAENSGVRGCMVIKPYGYAIWEKMQAELDRMFKETGHSNAYFPLFVPKSMFEAEEKNAEGFAKECAIVTHYRLKNDPDKPGKLMVDPNAKLEEELIVRPTSEAIIWSTYKGWIQSYRDLPLLINQWANVVRWEMRTRLFLRTAEFLWQEGHTAHATRKEAIEESEKMMNVYADFAQNFMAIPVIKGLKTETERFAGAEETYCIEALMQDGKALQAGTSHFLGQNFAKAFDVKFANAEGKQEHVWGTSWGVSTRLMGALVMTHSDDNGLVLPPNLAPIQVVIVPIFKTDEEFEKISALANDLISQFKKLNISVKFDNRTTQKPGFKFAEWELKGVPVRIAIGPKDLENETFEIARRDTLTKEVKPKEGIVKYISDLLAQIQSDLFSKALQYRDTHITEVSDFEEFKKVLENKGGFISAHWDGTPETEEKIKELTKATIRCIALNRKEEIGNCMFTGKQSVGRVLFAKAY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AT1B1_MOUSE
Sequence: MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISELKPTYQDRVAPPGLTQIPQIQKTEISFRPNDPKSYEAYVLNIIRFLEKYKDSAQKDDMIFEDCGNVPSEPKERGDINHERGERKVCRFKLDWLGNCSGLNDDSYGYREGKPCIIIKLNRVLGFKPKPPKNESLETYPLMMKYNPNVLPVQCTGKRDEDKDKVGNIEYFGMGGYYGFPLQYYPYYGKLLQPKYLQPLLAVQFTNLTVDTEIRVECKAYGENIGYSEKDRFQGRFDVKIEIKS
What is the function of this protein?
Involved in cell adhesion and establishing epithelial cell polarity.
What are the official names of this protein?
Sodium/potassium-transporting ATPase subunit beta-1, Sodium/potassium-dependent ATPase subunit beta-1.
What is the protein family that this protein belongs to?
Belongs to the X(+)/potassium ATPases subunit beta family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Apical cell membrane; Single-pass type II membrane protein. Cell membrane, sarcolemma. Note=Colocalizes with OBSCN at the intercalated disk and sarcolemma in cardiomyocytes. Localizes in long striations at the level of Z and M lines.
Protein: YPT11_YEAS6
Sequence: MSQRKRYSLNVVTSPSIPSPTPSAPIRTNESNWEAASPASAASSFLPNVHHGGTVLNPGLGIMRSPSLNKSGAFGRSGSSGSSTVIEPSNIKLLLIGDANVGKTAMILSYCRELLTRAEMSRSARLRHQQQQQHKDLGLKKTVVNHRLSMKEKRKRYSSNDFEKEFKDINHFADETSDFGNPNIGDDNNHEMADPNEIVIETRSTIGIDIKTNLVNIDNRFFNVILWDTAGQERYQNAIIPSLYKKTNAVILTYDITNAKSFQSCMERWIVQALENFSSQDLLKARFFLVGNKIDLYKERQVTHYDVVQMVQEMQLKHGIKISGNFEVSCKWVNVVERTMNMIILDLVENGCFENNDPCVSITTSDDVQGHEQEFHDTVEEPFNFTRQRQHQLEKNNTVDITKPNDDIANNQSICCV
What is the function of this protein?
Involved in the positive control of both endoplasmic reticulum (ER) and mitochondrion inheritance during cell divison.  Required for the MYO2-dependent retention of newly inherited mitochondria at the bud tip in developing daughter cells (By similarity).
What are the official names of this protein?
GTP-binding protein YPT11, Rab GTPase YPT11.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Lipid-anchor; Cytoplasmic side. Bud tip. Bud neck. Note=Enriched in the peripheral ER of small buds and daughter cells. Concentrates at the site of bud emergence, at the bud tip of the growing bud, and at the bud neck during the M phase. Interaction with MYO2 is required for proper localization to the bud (By similarity).
Protein: SUMT_CYACA
Sequence: MTHNKTIKKVYIVGAGPGDPELLTLKAQRVLREADVVIYDALVNPEILQHCKPNAEIIKVGKRRNNHSFSQLQIASLLIDRAKKGERVIRLKGGDPLIFGRLGEEILELFSKNIEIEIIPGITSAFAVAADMKFPLTHRQLGSSITFLTGEEFYEKTTNKLKWERIIWGADTIIVYMILYNLPKIIKKFLSVGYSAEKPIVLVQWASLKKKNFLIGTIGTIIHQVIESKFGPPSLAIIGEVIEISSIIQKL
What is the function of this protein?
Catalyzes the two successive C-2 and C-7 methylation reactions involved in the conversion of uroporphyrinogen III to precorrin-2 via the intermediate formation of precorrin-1.  It is a step in the biosynthesis of both cobalamin (vitamin B12) and siroheme.
What are the official names of this protein?
Uroporphyrinogen-III C-methyltransferase, Urogen III methylase, S-adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT, Uroporphyrinogen III methylase, UROM.
What is the protein family that this protein belongs to?
Belongs to the precorrin methyltransferase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CYTN_HUMAN
Sequence: MAQYLSTLLLLLATLAVALAWSPKEEDRIIPGGIYNADLNDEWVQRALHFAISEYNKATKDDYYRRPLRVLRARQQTVGGVNYFFDVEVGRTICTKSQPNLDTCAFHEQPELQKKQLCSFEIYEVPWENRRSLVKSRCQES
What is the function of this protein?
Human saliva appears to contain several cysteine proteinase inhibitors that are immunologically related to cystatin S but that differ in their specificity due to amino acid sequence differences.  Cystatin SN, with a pI of 7. 5, is a much better inhibitor of papain and dipeptidyl peptidase I than is cystatin S, although both inhibit ficin equally well.
What are the official names of this protein?
Cystatin-SN, Cystain-SA-I, Cystatin-1, Salivary cystatin-SA-1.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSAD_CYAPA
Sequence: MNAFVASVAPIAVAGSATLSSAVCAQKKAFFGAQVAAKKTTFEAAPARFIVRAEEEEAAPAEKVEKKAAAPKPFSVPTLNLNAPTPIFGGSTGGLLRKAEVEEFYSITWTGKSETVFELPTGGAAIMRAGENLLRLARKEQCIALGAQLKDKFKITDYKIYRVYPSGEVQFLHPKDGVFPEKVNPGRVAVGSNKRRIGQNPDPAKLKFKGQETFDSDLKL
What is the function of this protein?
PsaD can form complexes with ferredoxin and ferredoxin-oxidoreductase in photosystem I (PS I) reaction center.  PSAD may encode the ferredoxin-docking protein (By similarity).
What are the official names of this protein?
Photosystem I reaction center subunit II, cyanelle, Photosystem I 20 kDa subunit, PSI-D.
What is the protein family that this protein belongs to?
Belongs to the PsaD family.
What are the subcellular locations of this protein?
Plastid, cyanelle thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: RF1_COLP3
Sequence: MKSSVYQKLEVLVERFEEVQALLSDPATISDQEKFRALSKEFKQLDAVTSVFNNYKSAEDDFSTAELMLKDDDPDMREMAQEEFKDAKKAVADIADELQILLLPRDPNDDNNCFVEIRAGAGGDEAAIFAGDLFRMYSRYAEKKGWKIEVMNSNESEQGGYKELIMKVNGEGVFGHMKFESGGHRVQRVPATESQGRVHTSACTVVVMPEIPEADAIEINKADLKVDTFRASGAGGQHVNKTDSAIRITHIPTGVVVECQEQRSQHKNRAQAMSVLQARLQQAEDEKRRSEEESSRRNLVASGDRSERIRTYNFPQGRMSDHRINLTLYRLNEIMEGSLQLVMEPIMQENQADLLAELAEQH
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ULAB_SALTY
Sequence: MTVRILAVCGNGQGSSMIMKMKVDQFLTQSNIDHTVNSCAVGEYKSELSGADIIIASTHIAGEISVTGNKYVVGVRNMLSPADFGPKLLEVIKEHFPQDVK
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II UlaABC PTS system is involved in ascorbate transport.
What are the official names of this protein?
Ascorbate-specific PTS system EIIB component, Ascorbate-specific phosphotransferase enzyme IIB component.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: U79A2_STERE
Sequence: MSLKGNDKELHLVMFPFFAFGHITPFVQLSNKISSLYPGVKITFLAASASVSRIETMLNPSTNTKVIPLTLPRVDGLPEGVENTADASPATIGLLVVAIDLMQPQIKTLLANLKPDFVIFDFVHWWLPEIASELGIKTIYFSVYMANIVMPSTSKLTGNKPSTVEDIKALQQSYGIPVKTFEAISLMNVFKSFHDWMDKCINGCNLMLIKSCREMEGSRIDDVTKQSTRPVFLIGPVVPEPHSGELDETWANWLNRFPAKSVIYCSFGSETFLTDDQIRELALGLELTGLPFFLVLNFPANVDKSAELKRTLPDGFLERVKDKGIVHSGWVQQRHILAHDSVGCYVFHAGYGSVIEGLVNDCQLVMLPMKVDQFTNSKVIALELKAGVEVNRRDEDGYFGKDDVFEAVESVMMDTENEPAKSIRENHRKLKEFLQNDEIQKKYIADFVENLKAL
What is the function of this protein?
May glycosylate diterpenes or flavonols in leaves.
What are the official names of this protein?
UDP-glycosyltransferase 79A2.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: CISY_CITMA
Sequence: MASLRSATALSRLRSRAGQQSNLSNSVRWLQMQSSADLDLHSQLKEMIPEQQERLKKVKSDLGKAQLGNITIDVVIGGMRGMTGLLWETSLLDPDEGIRFRGLSIPECQKLLPAAKPDGEPLPEGLLWLLLTGKVPSKEQVDGLSKELRDRATVPDYVYKAIDALPVSAHPMTQFASGVMALQVQSEFQEAYEKGIHKSKSWEPTSEDSLNLIARVPVVAAYVYQRIYKDGKIIPKDDSLDYGGNFSHMLGFDDPKMLELMRLYVTIHSDHEGGNVSAHTGHLVASALSDPYLSFLAALNGLAGPLHGLANQEVLLWIKSVVDECGENVTTEQLKDYVWKTLNSGKVVPGFGHGVLRKTDPRYTCQREFALKHLPDDPLFQLVSKLYEVVPPILTKLGKVKNPWPNVDAHSGVLLNHFGLAEARYYTVLFGVSRSLGICSQLIWDRALGLPLERPKSVTLDWIEKNCKKAA
What are the official names of this protein?
Citrate synthase, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: TGT_HELHP
Sequence: MQVTLQAQDGGARALSLKLAHSEVQTPVFMPVGTQGCVKALDSRDMSEILNAQIILVNTYHMYLRIGIERLKNFGGIARFAHFDRSYLSDSGGFQAFSLNKNAKVTNEGVAFKSHIDGSKHFFSPEYVLDIQYALNSDIMMVLDDLVGLPSSEERIADSIARTSDWAQKSLIYHQSQKARGLGLNNNLFAIIQGGVNEHFRTLCAKQLVDMGDFDGFAIGGLAVGETSEQMYKTISFTTPLMPVNKPRYLMGVGTPENIIESIALGVDMFDCVMPTRNARNATLFTHFGKINIKAAIFSNDQSPIDELCDCYTCQHFTRAYLCHLFRSQEMTYYRLASLHNLHYYLNLMREAREAILQGTFSAYRSSFYALREMEIPNNEY
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.