PharMolix/UniProtQA huggingface dataset:
Protein: CAIA_CONGE
Sequence: ECCNPACGRHYSCGK
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.
What are the official names of this protein?
Alpha-conotoxin GIA.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: OTSB_MYCTU
Sequence: MRKLGPVTIDPRRHDAVLFDTTLDATQELVRQLQEVGVGTGVFGSGLDVPIVAAGRLAVRPGRCVVVSAHSAGVTAARESGFALIIGVDRTGCRDALRRDGADTVVTDLSEVSVRTGDRRMSQLPDALQALGLADGLVARQPAVFFDFDGTLSDIVEDPDAAWLAPGALEALQKLAARCPIAVLSGRDLADVTQRVGLPGIWYAGSHGFELTAPDGTHHQNDAAAAAIPVLKQAAAELRQQLGPFPGVVVEHKRFGVAVHYRNAARDRVGEVAAAVRTAEQRHALRVTTGREVIELRPDVDWDKGKTLLWVLDHLPHSGSAPLVPIYLGDDITDEDAFDVVGPHGVPIVVRHTDDGDRATAALFALDSPARVAEFTDRLARQLREAPLRAT
What is the function of this protein?
Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
What are the official names of this protein?
Trehalose-phosphate phosphatase, TPP, Trehalose-6-phosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the trehalose phosphatase family.
Protein: Y4501_PHOLL
Sequence: MNATENFQIIHRYLARQHVLTLCTATGDDVWCANCFYVFNADEIAFWFMTELHTRHGEMMQVNPQVAGTIAGQIRHIAQIKGIQFKGEVIRLEGEKDKVARARYCRRFPVSIAVKTPIWQLNLNEIKMTDNTLGFGKKICWQR
What are the official names of this protein?
UPF0306 protein plu4501.
What is the protein family that this protein belongs to?
Belongs to the UPF0306 family.
Protein: WSCD2_DANRE
Sequence: MARSLLKIHRYFRRKPVRFFSFILLYLTAGSLVFLHSGFSSDSSTAGIAGSGSDPLLSEGRGGTGGGSATSEGLGLLGRVFKETRRTPRRFGPPWMKESRGQDAPEWAGRGFDHTSSWSHGAKGRTTKEMDDGRAKYIGCYVDDTQKRALRGVSFLDYKKMTVFRCQDNCAERGYLYAGLEFGAECYCGHKIQAPNVSESECNMECKGEKSNLCGGPNRLSIYRLELSQESARRYGSAIFKGCFRRPDNVTLALPASAVMQNMSVDKCVDMCTEKEFSLAALAGDKCHCGFPTPLFNLHEHEDEELCLHRCTGEDFESCGNRDFFVVYQTQVQDNRCMDRRFLPTRSKHLMALASFPGAGNTWARHLIELATGYYTGSYYFDGSLYNKGFKGERDHWRSGRTICIKTHESGKKEIETFDASILMIRNPYKALMAEFNRKYGGHIGFASQAHWRGKEWPEFVKNYAPWWASHTLDWLKYGKKVQVVHFEDLKRDLFSQLKGMVIFLGLEVSEDRLLCVEGQKDGNFKRSGLRKLEYDPYTVEMRATIDRLIKTVDMELRKRNLSGVPDEYRPR
What is the function of this protein?
Sialate:O-sulfotransferase which catalyzes 8-O-sulfation at the Sia-glycan level using 3'-phosphoadenosine 5'-phosphosulfate (PAPS) as a donor, forming 8-O-sulfated Sia (Sia8S)-glycans.
What are the official names of this protein?
Sialate:O-sulfotransferase 2, WSC domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the WSCD family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CLC91_CAEEL
Sequence: MRSTYILIIVPLIIIGGGVVADNTNETPVLAHSSDEQPHQRLTYYNWDHKDLGTSAFEDLPPLQDQPTPLPIDQSDRCPDGWLRYSDSCYFIETESLGFAKAERKCHDKQATLFVANSMEEWDAVRDHAEKSVLSWIGLVRFSHYERLEQLPRWQTTGSINPSKINWLIKPFKPVVNGWSSYANCAASFQSPTEVESASYTFFYPCTMAFKSICERNSTILNARN
What are the official names of this protein?
C-type lectin domain-containing protein 91.
What are the subcellular locations of this protein?
Secreted.
Protein: RPOZ_FRASN
Sequence: MSGTVAQPEGITNPPIDELLEATDSKYSLVIYAAKRARQINAYYSQLGEGLLEYVGPLVETTSAQEKPLSIALREINSGLLTHETITDPLPPIS
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: YR7C_ECOLX
Sequence: MAIEGAAATVPLSPGERLNGLNHIAELRAKVFGLNIESELERFIKDMRDPRDINNEQNKRALAAIFFMAKIPAERHSISINELTTDEKRELIKAMNHFRAVVSLFPRRLTMPN
What are the official names of this protein?
Protein ORFc in retron Ec67.
Protein: RPOC2_PINTH
Sequence: MKIWRFFLMKERTRLPFDNLPFYNKVMDKTAIKKLISRLIDHFGMTYTSHILDQLKTSGFQQATDTAISLGIDDLLTAPSKGWLVQDAEQQGSVSEKQNHYGNVHAVEKLRQSIEIWYATSEYLRKEMNPNFSMTDPLNPVHVMSFSGARGSTSQVHQLVGMRGLMSDPQGQIIDLPIRRNLREGLSLTEYIISCYGARKGVVDTAVRTADAGYLTRRLVEVVQHIVVRRTDCGTIQGIFVSPIRGRERDRNEIVVRTQILIGRVLADDVYINRRCIATRNQDIGVGLANQLINLRTQPIYIRTPFTCKSISRICQLCYGRSTTHSHLIELGEAVGIIAGQSIGEPGTQLTLRTFHTGGVFTGDIAEHIRAPFNGKIEFNENLVYPTRTRNGHPAYLCHNNLSITIDGQDQVQNLTIPPQSLLLVQNDQYVESEQLIAEVRARTSSFKEKVRKNIYSDLEGEMHWSTNVCHAPEYVQGNVHPILRTGYLWILSGGIYGSRVVPFPFHKYQDQVYVQPFVAKHQSLSDSYVDQVEHRSGDSNCYEKEEQIFSYSETETDRTISNKHRDSIYVFYPNNYNIKGKKQMNRFIVSLQCDKEWEKKIIPCPDAILRIPKSGILQRNSIFGYSNVEHGIPDGSNMTTPFSLDLSREGDNLQIQISYSISYEDGERIQVMSDISIPLVRTCIGFDWEQIDSIESEAYVSLISVRTNKIVNNMVQISLMKYPPFFMGRRDNKTSPNLMFHNNLDHTNLLSSNGASQLISKHQGIICSLSNGEEDSGSFMVLSPSDYFRIVLFNDSKCYDTGNQSNRKDPMRKIIEFSGLLGNLHSITNRFPSSHFLTYKKVLSKKHSIFHNSFNTFQVPKYYFMDENMIIYHFDPCRNIISNLLGPNWCSSSSESEFCEKTFPVVSLGQLIPESVWISEDEPLPESGQIIAVDEESLVIRSAKPYLATRKATVHSHYGKILDKGDTLITLIYERFKSSDIIQGLPKVEQLSEARLNNSISMNLKESFENWTGDMTRFLGSLWGLFISARITMEQSQIHLVNQIQKVYRSQGVRIGDKHIEVIVRQMTSKVLISEDGTANVFSPGELIVLSRAQRMDRALEEAIYYQTMLLGITRASLNTQSFISEASFQETARVLAKAALQGRIDWLKGLKENVILGGMIPAGTGQHIHRSGKRNGIDPRIGNRNLFSNKVKDILFHHDKVDFFSFQDNSYKYHNILKQQLK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta'', PEP, Plastid-encoded RNA polymerase subunit beta'', RNA polymerase subunit beta''.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HIS3_NEIG1
Sequence: MDKNLLEAVKFDEKGLVCAIAQDAETKRVLMVAWMNAEALQKTVETGFAHYYSRSRQKQWMKGEESGHTQKVRELRLDCDGDTIVMLIAQNGGIACHTGRESCFYKKWNGGAWETADAVLKDEKEIYGSTH
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNP4_HALS3
Sequence: MASIAAERIDRLHTLARAAARTGDDDRAREYVRLARRLAERNRLTLPPAFRRFTCDDCDAVLVPGRNARVRTRSGHVVVTCDCGTHARYPYTG
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 4, RNase P component 4, Rpp21.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPA_LEUCK
Sequence: MRKTFRIKKPADFQIVFNKHQSVANKYFIVYHIDKPEQKHFRLGLSVSKKVGKAHDRVWVKRRIRQSILELKSDLPHDIDLLVIARPAVAKQSQKFIKEQIIHVLKLADILKVEDK
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: PRDX6_CHICK
Sequence: MPGLLLGDEAPNFEADTTQGGIRFHDFLGDSWGILFSHPRDFTPVCTTELGRAAKLAPEFSKRNVKMIALSIDSVPDHLAWSKDINAYNGDQPVEKLPFPIIADKDRELAVKLGMLDPDERDKDGMPLTARVVFIFGPDKKLKLSILYPATTGRNFDEILRVVDSLQLTAYKKVATPVDWKCGDSVMVVPTLPDEEAKKLFPKGVFTKDLPSGKKYLRYTPQPE
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively (By similarity).  Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides (By similarity).  Also has phospholipase activity, and can therefore either reduce the oxidized sn-2 fatty acyl group of phospholipids (peroxidase activity) or hydrolyze the sn-2 ester bond of phospholipids (phospholipase activity) (By similarity).  These activities are dependent on binding to phospholipids at acidic pH and to oxidized phospholipds at cytosolic pH (By similarity).  Plays a role in cell protection against oxidative stress by detoxifying peroxides and in phospholipid homeostasis (By similarity).  Exhibits acyl-CoA-dependent lysophospholipid acyltransferase which mediates the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC) (By similarity).  Shows a clear preference for LPC as the lysophospholipid and for palmitoyl CoA as the fatty acyl substrate (By similarity).
What are the official names of this protein?
Peroxiredoxin-6, 1-Cys peroxiredoxin, 1-Cys PRX, Acidic calcium-independent phospholipase A2, aiPLA2, Glutathione-dependent peroxiredoxin, Lysophosphatidylcholine acyltransferase 5, LPC acyltransferase 5, LPCAT-5, Lyso-PC acyltransferase 5, Non-selenium glutathione peroxidase, NSGPx.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. Prx6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Lysosome. Note=Also found in lung secretory organelles (lamellar bodies).
Protein: FLGI_PSEU2
Sequence: MIKLKQLIAATLLLSTAFGVHAERLKDIASISGVRANQLIGYGLVVGLNGTGDQTTQTPFTLQTFNNMLSQFGIKVPAGSGTVQLKNVAAVAVYADLPAFAKPGQTVDITVSSIGNSKSLRGGALLMTPMKGVDGNVYAIAQGNLVVGGFDAEGRDGSKITVNVPSSGRIPGGASVERSVPSGFNQGNTLTLNLNRSDFTTAKRIVDKINELLGPGVAQALDGGSVRVTAPLDPGQRVDYLSILENLEVDPGQTAAKVIINSRTGTIVIGQNVKVSPAAVTHGSLTVTITEDPIVSQPGALSGGQTAVVPRSRVNAQQELHPMFKFGPGTTLDEIVRAVNQVGAAPGDLMAILEALKQAGALQADLIVI
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: DDLA_SALTI
Sequence: MAKLRVGIVFGGKSAEHEVSLQSAKNIVDAIDKTRFDVVLLGIDKAGQWHVNDAENYLQNADDPAHIALRPSAISLAQVPGKHQHQLINAQNGQPLPTVDVIFPIVHGTLGEDGSLQGMLRVANLPFVGSDVLSSAACMDKDVAKRLLRDAGLNIAPFITLTRTNRHAFSFAEVESRLGLPLFVKPANQGSSVGVSKVANEAQYQQAVALAFEFDHKVVVEQGIKGREIECAVLGNDNPQASTCGEIVLNSEFYAYDTKYIDDNGAQVVVPAQIPSEVNDKIRAIAIQAYQTLGCAGMARVDVFLTADNEVVINEINTLPGFTNISMYPKLWQASGLGYTDLISRLIELALERHTANNALKTTM
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase A, D-Ala-D-Ala ligase A, D-alanylalanine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MBI3_NEUCR
Sequence: MRLLKSHPLLKLVNSYLIDASQPSNISYLWNFGSLLACCLIIQIVTGVTLAMHYSPNVLEAFNSIEHIMRDVNNGWLVRYLHSNTASAFFFLVYLHIGRGMYYGSYRAPRTLVWAIGTVILILMMATAFLGYVLPYGQMSLWGATVITNLISAIPWIGQDIVESKIITLIINLSFIAILFSIVVVYYYILLHVNFSSNLPTIGVIHQNALKKSNKALRLDKQEYISIPSSFLAFLAGLVDGDGYIQVTKTSKGFIAIKLVISLHLEDLSILEYIHSVLKIGKINIYKDLRSPTCKLVINKTDLQEILFPLLMYNKIFFLTNTRADQFNLAMYIFKNDIKMYNQIPDNTPAVFEIPKNPIDYTLLPFFKNWIVGFTCSEGSFFIKSNNDGCFQLKQRIHTNLFEAFKLMFNTNRKIDTTNNFNQFGVSSKSDIQKVINFFSFSGLHPLVGLKYIQYIKWLNNLRESLRYSTLNYPDAK
What is the function of this protein?
Mitochondrial mRNA maturase required for splicing of intron 3 of the cytochrome b (cob) gene, containing its own coding sequence.
What are the official names of this protein?
Cytochrome b mRNA maturase bI3.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the LAGLIDADG endonuclease family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: UVRB_THEVB
Sequence: MTSTPFRIHAPFEPTGDQPQAIQKLVAGVQAGHRFQTLLGATGTGKTHTIARVIEALGRPTLVLAHNKTLAAQLCNELRSFFPENAVEYFISYYDYYQPEAYIPVTDTYIEKSASINEEIDMLRHSATRSLFERRDVIVVASISCIYGLGIPAEYLKAAIPLEVGRETELRQLLRQLATIQYTRNDVELGRGRFRVRGDVLEIGPAYEDRIIRVEFFGDEIEAIRYVDPLTGETLQSVERLNIYPAKHFVTPAERLEAACVAIEAELQAQVANLEAQNKLLEAQRLSQRTRYDLEMLRQVGYCNGVENYSRHLAGRAAGEPPECLIDYFPENWLLVVDESHVTVPQIRGMYNGDQARKKVLIDHGFRLPSAADNRPLKPEEFWQKVQQCIFVSATPGDWELAVSTQVVEQIIRPTGVVDPEIFVRPTQGQVDDLYGEIRLRCDRQERVLVTTLTKRMAEDLTEYFQERGVRVRYLHSEINAIERIEILEALRQGDFDVLIGVNLLREGLDLPEVSLVAILDADKEGFLRAERSLIQTIGRAARHVRGQAILYADTLTESMQKAIQETERRRAIQLAYNQAHGIIPQPIVKKTSNAILAFLDVSRRLNAESVPVLSSQTLQDLSLEDIPPLIQDLEAKMKAAAQELAFEEAARYRDQIKRLRDRLVGHP
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WDR20_MOUSE
Sequence: MATEGRGKETNEIKTHFTTREGLYRLLPHSEYSRPNRVPFNSQGSNPVRVSFVNLNDQTGNGNRLCFSVGRELYVYIYKGVRKAADLSKPIDKRIYKGTQPTCHDFNHLTATAESVSLLVGFSAGQVQLIDPIKKETSKLFNEERLIDKSRVTCVKWVPGSDSLFLVAHSSGNMYSYNVEHTYGTTAPHYQLLKQGESFAVHNCKSKSTRDLKWTVGEGALNEFAFSPDGKFLACVSQDGFLRVFNFDSAELHGTMKSYFGGLLCLCWSPDGKYIVTGGEDDLVTVWSFLDCRVIARGRGHKSWVSVVAFDPYTTSVEESDPMEFSDSDKNFQDLLHFGRDRANSTQSRLSKQNSTDSRPVSVTYRFGSVGQDTQLCLWDLTEDILFPHQPLSRARAHANVMNATGLPAGSNGSAVTTPGNSVPPPLPRSNSLPHSAVSNAASKGSVMDGAITSGVSKFALLSLHDRKERHHEKDRKRNHSMGHISSKSSDKLNLVNKAKTDPAKTLGTSLCPRMEDVPLLEPLICKKIAHERLTVLVFLEDCIVTACQEGFICTWARPGKVSKFQP
What is the function of this protein?
Regulator of deubiquitinating complexes.  Activates deubiquitinating activity of complexes containing USP12.
What are the official names of this protein?
WD repeat-containing protein 20.
Protein: CIPKN_ARATH
Sequence: MASRTTPSRSTPSRSTPSGSSSGGRTRVGKYELGRTLGEGTFAKVKFARNVENGDNVAIKVIDKEKVLKNKMIAQIKREISTMKLIKHPNVIRMFEVMASKTKIYFVLEFVTGGELFDKISSNGRLKEDEARKYFQQLINAVDYCHSRGVYHRDLKPENLLLDANGALKVSDFGLSALPQQVREDGLLHTTCGTPNYVAPEVINNKGYDGAKADLWSCGVILFVLMAGYLPFEDSNLTSLYKKIFKAEFTCPPWFSASAKKLIKRILDPNPATRITFAEVIENEWFKKGYKAPKFENADVSLDDVDAIFDDSGESKNLVVERREEGLKTPVTMNAFELISTSQGLNLGSLFEKQMGLVKRKTRFTSKSSANEIVTKIEAAAAPMGFDVKTNNYKMKLTGEKSGRKGQLAVATEVFQVAPSLYMVEMRKSGGDTLEFHKFYKNLTTGLKDIVWKTIDEEKEEGTDGGGTNGAMANRTIAKQST
What is the function of this protein?
CIPK serine-threonine protein kinases interact with CBL proteins.  Binding of a CBL protein to the regulatory NAF domain of CIPK protein leads to activation of the kinase in a calcium-dependent manner.  Downstream of CBL1, CBL2, CBL3 and CBL9, regulates by phosphorylation the K(+) conductance and uptake of AKT1 in low K(+) condition, in response to calcium signaling and during the stomatal opening regulation by monitoring the turgor pressure in guard cells.  In response to low nitrate concentration, phosphorylates NRT1. 1, switching it from a low-affinity nitrate transporter to a high-affinity transporter.  Confers tolerance to low potassium conditions.  Involved in drought sensitivity and leaf transpiration.
What are the official names of this protein?
CBL-interacting serine/threonine-protein kinase 23, Protein LOW-K(+)-SENSITIVE 1, SNF1-related kinase 3.23, SOS2-like protein kinase PKS17.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Note=Associated to the plasma membrane when associated with AKT1, CBL1 and CBL9.
Protein: METK_STRU0
Sequence: MSERKLFTSESVSEGHPDKIADQISDAILDAILAEDPEAHVAAETVVYTGSVHVFGEISTSAYVDINRVVRDTIAEIGYTNAEYGFSANSVGVHPSLVEQSTDIAQGVNEALEAREGQKDDLNLIGAGDQGLMFGFAIDETPELMPLPISLSHKLVKKLADLRKSGDITYLRPDAKSQVTVEYDDNDQPVRVDTVVISTQHDPEVSQETIRHDVIEKVIKEVIPTSFIDDNTKYFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFSGKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTSTVSETDIEKAVRQLFDLRPAGIIKMLDLKRPIYKQTAAYGHMGRTDIDLPWEKLDKVEALKQLIG
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGT_LACLA
Sequence: MTEHAIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQATVKTMSPEELKTLGSGIILSNTYHLWLRPGDELVAEAGGLHKFMNWDQPILTDSGGFQVYSLVQNKKNITEEGVKFKSHLDGRELFLNPEKAISIQNNLGSDIMMSFDECPPFYQPYDYVKASVERTSRWAERGLNAHRRPNDQGLFGIVQGAGFEDLRRQSARDLTSMDFAGYSIGGLAVGESHKEMNAVLDFTTPMLPEDKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTRIARNGTLMTHFGRVNIRNAKYEHDFTPLDPMCDCYTCTNYTRAYLRHLIKADETFGLRLCSYHNLHFLVNLMKDVRGAIMDDNLLEFREDFCERYGYNQPNAKDF
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: EF104_ARATH
Sequence: MATKQEALAIDFISQHLLTDFVSMETDHPSLFTNQLHNFHSETGPRTITNQSPKPNSTLNQRKPPLPNLSVSRTVSTKTEKEEEERHYRGVRRRPWGKYAAEIRDPNKKGCRIWLGTYDTAVEAGRAYDQAAFQLRGRKAILNFPLDVRVTSETCSGEGVIGLGKRKRDKGSPPEEEKAARVKVEEEESNTSETTEAEVEPVVPLTPSSWMGFWDVGAGDGIFSIPPLSPTSPNFSVISVT
What is the function of this protein?
Probably acts as a transcriptional activator.  Binds to the GCC-box pathogenesis-related promoter element.  May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
What are the official names of this protein?
Ethylene-responsive transcription factor ERF104.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PYRH_SYNE7
Sequence: MAYKRVLLKLSGEALMGDASYGIDPAVVQRIAQEIATVVQDGFQVAIVVGGGNIFRGIKGAAAGMERATADYVGMIATVMNAITLQDALEQLQVPTRVQTAIAMQEVAEPYIRRRAIRHLEKGRVVIFGSGTGNPFFTTDTTAALRAAEINADVVFKATKVDGVYDSDPKLNPQARRFTTLNYNYVLNHELGVMDSTAIALCKDNSIPIVVFDLFGEGNIRRAVQGEDIGTTVGGSCEVS
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS1_STRR6
Sequence: MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGVLTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKLVGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKEVNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDGLVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKLAKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVLEVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMADLFGDIEL
What is the function of this protein?
Binds mRNA; thus facilitating recognition of the initiation point.  It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity).
What are the official names of this protein?
30S Ribosomal protein S1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS1 family.
Protein: Y1858_ALTMD
Sequence: MAFDKKLLEVLACPVCKGKLVLNEDMTQLVCRFDRLAFDIKDGIPVLIESKATALSLDEVDATR
What are the official names of this protein?
UPF0434 protein MADE_1009415.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: PSLS_BACSU
Sequence: MNDFSLELPVRTNKPRETGQSILIDNGYPLQFFKDAIAGASDYIDFVKFGWGTSLLTKDLEEKISTLKEHDITFFFGGTLFEKYVSQKKVNEFHRYCTYFGCEYIEISNGTLPMTNKEKAAYIADFSDEFLVLSEVGSKDAELASRQSSEEWLEYIVEDMEAGAEKVITEARESGTGGICSSSGDVRFQIVDDIISSDIDINRLIFEAPNKTLQQGFIQKIGPNVNLANIPFHDAIALETLRLGLRSDTFFL
What is the function of this protein?
Catalyzes the addition of sulfite to phosphoenolpyruvate (PEP) to yield (2R)-phospho-3-sulfolactate (PSL) (By similarity).  Is probably involved in the biosynthesis of L-sulfolactate, which is a major constituent of sporulating cells and mature spores.
What are the official names of this protein?
Phosphosulfolactate synthase, (2R)-phospho-3-sulfolactate synthase, PSL synthase.
What is the protein family that this protein belongs to?
Belongs to the phosphosulfolactate synthase family.
Protein: MSRA_STAAC
Sequence: MNINTAYFAGGCFWCMTKPFDTFDGIEKVTSGYMGGHIENPTYEQVKSGTSGHLETVEIQYDVALFSYNKLLEIFFSVIDPLDTGGQYQDRGPQYQTAIFYTNDHQKELAETYIEQLKNTINADKAIATKILPASQFYKAEDYHQDFYKKNPERYAEEQKIRQEYKNKQ
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: CLP1_NEUCR
Sequence: MSIPGLGQIAPQAPTTTQRTINLRPFGEWRFSIPHQHSTFSSNSSAAGVTVRLVAGTAERDGTELAPNCVYTFLPGTKSKLFTDQGCTLEINNTGGYPLEDRVVEHPPEQSPMLSYINLHFGLQDHERAAAAQAQQQHPTHHQQQQQGRGAGAGVARSKPGPRVLICGPPGVGKTSLAKLLAALATRMGSQPLVANLNPTDGLLCLPGTLGAAVFGTLMDVEEPAGGFGVTNTPISGPSAVPVKNPLTFYFGHEKVEDDVDMWRQMTERLAVLARRKFERNRDVRVAGLLVDTAPVEAGDKEGQELLGWAVRQFDANFVVVLGSEQLKTELGQRFASEKTSFEEPITVLGLDKSDGAVQIDKAWRQKSTETAIKEYFFGGIKARLSPFTQSASFDELVVFKAPDEPYEGAPVLERVEITPEMAHWTLAVMIASVTDSPQAIRFSSVLGFIVIADVDQERRRVKFLSPVSGRLGNHPLIWGRWPEPYLNLLA
What is the function of this protein?
Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.
What are the official names of this protein?
mRNA cleavage and polyadenylation factor clp1, Polyadenylation factor 7.
What is the protein family that this protein belongs to?
Belongs to the Clp1 family. Clp1 subfamily.
What are the subcellular locations of this protein?
Nucleus.