PharMolix/UniProtQA huggingface dataset:
Protein: TKN2_PHLMA
Sequence: DPPDPDRFYGMM
What is the function of this protein?
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.
What are the official names of this protein?
Hylambatin.
What is the protein family that this protein belongs to?
Belongs to the tachykinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: METE_ECO5E
Sequence: MTILNHTLGFPRVGLRRELKKAQESYWAGNSTREELLAVGRELRARHWDQQKQAGIDLLPVGDFAWYDHVLTTSLLLGNVPARHQNKDGSVDIDTLFRIGRGRAPTGEPAAAAEMTKWFNTNYHYMVPEFVKGQQFKLTWTQLLDEVDEALALGHKVKPVLLGPITWLWLGKVKGEQFDRLSLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELPQAWLDAYKPAYDALQGQVKLLLTTYFEGVTPNLDTITALPVQGLHVDLVHGKDDVVELHKRLPSDWLLSAGLINGRNVWRADLTEKYVQIKDIVGKRDLWVASSCSLLHSPIDLSVETRLDAEVKSWFAFALQKCHELALLRDALNSGDTAALAEWSAPIQARRHSTRVHNPAVEKRLAAITAQDSQRANVYEVRAEAQRARFKLPAWPTTTIGSFPQTTEIRTLRLDFKKGNLDANNYRTGIAEHIRQAIVEQERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPIVIGDVSRPAPITVEWAKYAQSMTDKPVKGMLTGPVTILCWSFPREDVSRETIAKQIALALRDEVADLEAAGIGIIQIDEPALREGLPLRRSDWDAYLQWGVEAFRINAAVAKDDTQIHTHMCYCEFNDIMDSIAALDADVITIETSRSDMELLESFEEFDYPNEIGPGVYDIHSPNVPSVEWIEALLKKAAKRIPAERLWVNPDCGLKTRGWPETRAALANMVQAAQNLRRG
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: STRO_STRGR
Sequence: MTDNDSDVRLAHRLAEIADTLAWEFFGGAPAVRHKSDGSPVSEADLAVEKALLAVLAAERPGDAVLTEESGSLGTRSSRRRWILDPIDGTIPFLAGERGWGTHVALEVDEELRTAVLSRPTERSRWWAVRGRGAFTSVRGEPLSAARPLRIPSAPLPLEAARVGGFLMPDSPVEPVRDRMRWVESSVCLVGDLLEGRVDAVIDEGGHVWDRAPAALLVHEAGGRVDDLRGGGRLDERWLVYAADGVADGLAGLLRDVGA
What are the official names of this protein?
Glucose-1-phosphate thymidylyltransferase, dTDP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the inositol monophosphatase superfamily.
Protein: LEXA_RHOPB
Sequence: MLTRKQYELLRFINERLKEAGVPPSFDEMKDALDLRSKSGIHRLITALEERGFIRRLPNRARAIEVIKLPELGVNPGGGNGRRGFTPSVIEGNLGRVRPAASLGGDDDSGRTVAVPVMGRIAAGTPIEALQTRSHTISMPADMLGSGEHYALEVRGDSMVDAGILDGDMALIQKNDSADTGDIVVALIDEEEATLKRFRRRGASIALEPANAAYEVRILPPNRVRIQGKLIGLYRKY
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: RL3_GRABC
Sequence: MRTGLIARKLGMTRLFKEDGTHVPVTVLHLDQVQVVDTRTKERDGYTAVQLGFGQAKPKHVSKANKGHFARVKVEPKKKLVEFRVAEDAILEPGATLSAEHFLVGQKVDVTGTSKGKGFAGAMKRWNFAGLEASHGVSISHRSHGSTGNRQDPGKTFKNKKMAGHLGDERVTTQNVEVAHVDAARGLLMIRGSIPGAKGGYVLVRDAVKRKRPEGVAYPAALQADAAASEG
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: Y950_STRM5
Sequence: MSTAPPSAPTLIIVSGLSGSGKSVALKTFEDQDYYCSDNLPINLLPDFVRSLLANHDGSAPRRLAVGIDVRGQSNLSQLGNWRQLATDAGVEVEVLFFEASDEAVLKRYADTRRRHPLSQLGLSLPEAIARERELTAPLRREADAVIDTSTLNVHQLRRRIITEFALDHATRLSLLFESFAYKRGVPAEADFVFDARVLPNPHWDPDLRALSGREPGVRDYLEAQPDVQHYLAQLTDFLDTWLPKLGDGTRSYVTVAFGCTGGKHRSVFLAERMARHAREMGWEDVATYHREQD
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Smal_0950.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: PALMD_BOVIN
Sequence: MEEAELVKERLQAITDKRKIQEEISQKRLKIEEEKLKHQHLKKKALREKWLLDGISSGKEQEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTNEEAILKKLKSVERTTEDIIRSVKVEKEETSGESVEDIYANIPDLPKSYIPSRLRKERNEGIEDDEQNRKALYAMEIKVEKDLKTGESTVLSSIPLPSDDFKGTGIKVYDDGQKSVYAVSSNHSAAYNGTDGLAPVEVEELLRQASERNSKSPTEYHEPVYANPFCRPTTPQREKVTPGPNFQERVKIKANGLGNDVNGSIHNIDNGLAEERGNNVNHISPARPIPHPRSMIQQAEEMPHIQQERLMTPWEEPNVMQDKYTPSPKSGLSPSRALVEKSERQSSSPPCQEDEKDIRYNIVHSLPSDLDEKEPVTMIFMGYQQAEDNEEEKKLLTGYDGIIHAELVVIDDEEEGEGEAEKPAYHPIAPHSQVFQPAKPTPLPRKRAEVNPHENTNHKSPHKNSISLKEQEESLGSPIHHSPLDVQIAGDGTEDPSLTALRMRMAKLGKKVI
What are the official names of this protein?
Palmdelphin.
What is the protein family that this protein belongs to?
Belongs to the paralemmin family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, dendrite. Cell projection, dendritic spine.
Protein: FMT_ALIF1
Sequence: MSKPLRIIFAGTPDFAARHLSALIDSHHEVIGVYTQPDRPAGRGKKLTASPVKELALEHNIPVFQPENFKSDEAKQELVDQNADLMVVVAYGLLLPQAVLDTPKLGCINVHGSILPRWRGAAPIQRSIWAGDAETGVTIMQMDIGLDTGDMLKIATLPIEATDTSASMYDKLAELGPVALVDCLSDIADGSAIAQKQDDELANYAKKLSKEEAKIDWTMDAIAIERCVRAFNPWPMSHFSVEDKAIKVWQSRVESYTGDATPGTIIQADKTGIYVATGSDAIVFEQLQVPGKKAMGVQDILNSRKEWFEVGNTLN
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: YNG1_YEAST
Sequence: MEHLANENSDSDIRYSFLSTLDHLPCELIRSLRLMQTIDLFKNEEDEPGMERACRDLLLVATYINDLVDDQIHFLKQHKKELEIQKSVTKNFNSSLENIKSKLTLEEPGAYKEPKLLLKINLKKAKSRERKESITSPTIGINQGDVTEGNNNQEEVYCFCRNVSYGPMVACDNPACPFEWFHYGCVGLKQAPKGKWYCSKDCKEIANQRSKSKRQKRRK
What is the function of this protein?
Histone-binding component of the NuA3 histone acetyltransferase complex, that acetylates Lys-14 of histone H3.  Recruitment of NuA3 to nucleosomes requires methylated histone H3.  In conjunction with the FACT complex, NuA3 may be involved in transcriptional regulation.  YNG1 is required for the HAT activity of NuA3 but not for its integrity.  Mediates the interaction of SAS3 with nucleosomes.
What are the official names of this protein?
Protein YNG1, ING1 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the ING family.
Protein: EXPB6_ARATH
Sequence: MASSSHRYFALLALFAVSLKFCYCQNETTDGAGWGTAGVTWYGEPLGAGSTGGACGFAVANPPLYGMVSAGGPSVFNNGIGCGTCFQILCNGHPACSRRPITVTITDECPGGPCASEPAHFDLSGKAMGALARPGQGDRLRSAGVLRVYYIRVECLYRRTNIAFRMDPGANPYYISFVVEYENGDGDLAYTEIQPAGGTFIPMQEMRSAVWKVNSGSPLTGPFNIRLTSAESHNVVVAYNVIPANWKPNETYRSVVNFK
What is the function of this protein?
May cause loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans.
What are the official names of this protein?
Expansin-B6, At-EXPB6, AtEXPB6, Beta-expansin-6.
What is the protein family that this protein belongs to?
Belongs to the expansin family. Expansin B subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Peripheral membrane protein.
Protein: DCTN5_DICDI
Sequence: MQVQPKYFEKSQYIETLNGNKVSKSSILCGIMNIRLHGKTIIKPGVIVRGDLASVNIGRLSIISENTVIRPSSKKFKGSLVYFPQNIGDHVLVGEGCVISAASIGSNVYIGNNCIISKRCILKDCCIIADNTILPPDTVVPPFTYYSGTPGVYKEDLPDCIEQFQKEYTTSLYESFLPNTPASKGLPSTPTKLQTTTT
What are the official names of this protein?
Dynactin subunit 5.
What is the protein family that this protein belongs to?
Belongs to the dynactin subunits 5/6 family. Dynactin subunit 5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RPOE_STRS7
Sequence: MKLDVFAGQEISELSMIEVARAILEERGRDNDMYFSDLVNEIQNYLGKSDADIRYALPFFYTDLNTDGSFIPLGENKWGLRSWYAIDEIDEEIITLEDEEDGAPKRKKKRVNAFMDGDEDAIDYSADDPEDEDFVRESSDIEYDEEDPDDEKSEVESYDSELNEIIPEDDFEEVDLNEEDEEDEDEEE
What is the function of this protein?
Participates in both the initiation and recycling phases of transcription.  In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
What are the official names of this protein?
Probable DNA-directed RNA polymerase subunit delta, RNAP delta factor.
What is the protein family that this protein belongs to?
Belongs to the RpoE family.
Protein: ERA_STRPB
Sequence: MFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKIMGIYTTETEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVETVLFMVPADEKRGKGDDMIIERLKAAKIPVILVINKIDKVHPDQLLEQIDDFRSQMDFKEVVPISALEGNNVPTLIKLLTDNLEEGFQYFPEDQITDHPERFLVSEMVREKVLHLTQQEVPHSVAVVVESMKRDEETDKVHIRATIMVERDSQKGIIIGKQGAMLKKIGKMARRDIELMLGDKVYLETWVKVKKNWRDKKLDLADFGYNEKEY
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: SSRP_ACTP2
Sequence: MAKKPKVASNTIALNKRARHEYFIEEEIEAGLELQGWEVKSLRAGKANIGDSYVTFRNGEAFLFGATITPLNMASTHIVCDPTRTRKLLLNKRELDSLFGKVNRDGMTVVALSLYWKNAWAKVKVGVAKGKKLHDKREDIKDREWQVAKQRIMKNANRG
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: Z_MACHU
Sequence: MGNCNKPPKRPPNTQTSAAQPSAEFRRTALPSLYGRYNCKCCWFADTNLITCNDHYLCLRCHQTMLRNSELCHICWKPLPTSITVPVEPSAPPP
What is the function of this protein?
Plays a crucial role in virion assembly and budding.  Expressed late in the virus life cycle, it acts as an inhibitor of viral transcription and RNA synthesis by interacting with the viral polymerase L.  Presumably recruits the NP encapsidated genome to cellular membranes at budding sites via direct interaction with NP.  Plays critical roles in the final steps of viral release by interacting with host TSG101, a member of the vacuolar protein-sorting pathway and using other cellular host proteins involved in vesicle formation pathway.  The budding of the virus progeny occurs after association of protein Z with the viral glycoprotein complex SSP-GP1-GP2 at the cell periphery, step that requires myristoylation of protein Z.  Also selectively represses protein production by associating with host eIF4E.
What are the official names of this protein?
RING finger protein Z, Protein Z, Zinc-binding protein.
What is the protein family that this protein belongs to?
Belongs to the arenaviridae Z protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm, host perinuclear region. Host cell membrane; Lipid-anchor; Cytoplasmic side. Note=Mainly perinuclear. During budding, associates at the inner side of the plasma membrane of infected cells.
Protein: ATPD_ACIC1
Sequence: MQGASRESLAAAWREAEELLVRPRPGAQPPEEVGTQLFSVTAILDEHPALRRALSDPAVEPGRKVSLADRLFGERIGETARRLVATVVRARWSRVRDLSDALETLGVLALLVAAERSRAVDDVEDELFRFGRIVASRPELRDALANRTLPVENKVRLVERLLADRAHPVTVALVTQLVRHPRGRTPEEGFADFSGIAARFRQRLVARVTTAVALTDDERSRLRRALSELYGRDVHLHVEVDPRIGGGVVVQLGDEVIDGSIASILAETRQRLAS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: UBIG_DINSH
Sequence: MTTNTQTVDTSELAKFEAMAAEWWDPMGKFRPLHLMNPVRLDYITRQIAAEYGRDLKSPNPFKGLRILDIGCGGGLLAEPMARLGATVVGADAAEGNLPVARLHAEKSGLEIDYRHTTAEALVAAGEQFDSVLNMEVVEHVADPLAYLTACKDLLKPGGIMLCSTLNRNPKSFAMAIVGAEYVLKWLPKGTHDWRKFLTPDELTKLLEQAGLEPVDKKGMVFNPLSQQWSLSDRDLSVNYVTASIRPA
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: MURA_SYNAS
Sequence: MDKIVIEGGKPLRGEVKISGAKNAALPIMASALLTEGWNTFHNIPDLMDIRTTRKLLQSLGVVIEGTSGTIRLNAGEISNIEASYDLVKTMRASILVLGPLVARLGIARVSLPGGCAIGARPVNLHIKALQEMGAEVILKEGYVEARAKRLKGANLYFDMPTVGGTENIMMAAALADGVTLLKNAAREPEIVNLAEVLNGMGAKVSGAGTDVIRVEGVERLHPVEADIIPDRIEAGTYMIAAGVTGGDIRVLGCCLSHLDALIEKLIDAGMTIEPFDGGLRAAGTGTIRSVDITTLPHPGFPTDLQAQMMSMMAVAEGLSVMTETVFENRFMHVGELMRMGADIQIQGNSAIVKGVGALKGAPVMATDLRASASLVLAGLAARGTTELSRVYHLDRGYEELEKKFSALGAEIRRISE
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_CHLP8
Sequence: MRYSSGAVEALIEEFAKLPGIGRKTAQRLTMHVLQERRGEVEKLAAALIDVKEKVVRCSICQNITDLGTDPCLLCTSTGRDRSVICVVESPTEVLAFEKTGHYKGLYHVLHGVISPLDGVGPDDIKVRELLARISPDSEGGVREVVLALNPTVEGETTSLYISKLLKPLGINVTRIARGIPVGAELEFIDEATLSRAMDGRSAV
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: TAF11_HUMAN
Sequence: MDDAHESPSDKGGETGESDETAAVPGDPGATDTDGIPEETDGDADVDLKEAAAEEGELESQDVSDLTTVEREDSSLLNPAAKKLKIDTKEKKEKKQKVDEDEIQKMQILVSSFSEEQLNRYEMYRRSAFPKAAIKRLIQSITGTSVSQNVVIAMSGISKVFVGEVVEEALDVCEKWGEMPPLQPKHMREAVRRLKSKGQIPNSKHKKIIFF
What is the function of this protein?
The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription (PubMed:33795473).  TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC) (PubMed:33795473).  The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13 (PubMed:33795473).  TAF11, together with TAF13 and TBP, play key roles during promoter binding by the TFIID and TFIIA transcription factor complexes (PubMed:33795473).
What are the official names of this protein?
Transcription initiation factor TFIID subunit 11, TFIID subunit p30-beta, Transcription initiation factor TFIID 28 kDa subunit, TAF(II)28, TAFII-28, TAFII28.
What is the protein family that this protein belongs to?
Belongs to the TAF11 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CEFF_STRCL
Sequence: MADTPVPIFNLAALREGADQEKFRECVTGMGVFYLTGYGAGDKDHRLATDTAMDFFANGTEAEKAAVTTDVPTMRRGYSALEAESTAQVTRTGSYTDYSMSFSMGISGNVFPSPEFERVWTEYFDKLYAAAQETARLVLTASGGYDAEIVGSLDELLDADPVLRLRYFPEVPEHRSAEHEPRRMAPHYDLSIITFIHQTPCANGFVSLQAEIGGELVSLPVVEDAVVVMCGAMAPLATQGALPAPRHHVRSPGAGMREGSDRTSSVFFLRPTTDFSFSVAKARSYGLAVDLDMETATFGDWIGTNYVTMHAKNEPQAG
What is the function of this protein?
Hydroxylation of desacetoxicephalosporin C in 3'position to form deacetylcephalosporin C.
What are the official names of this protein?
Deacetoxycephalosporin C hydroxylase, Beta-lactam hydroxylase, Deacetylcephalosporin C synthase, DACS.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: SYC_MOOTA
Sequence: MYLYNTLTGRKEEFTPVEPGRVRMYVCGPTTYNYIHLGNARPMVVFDTLRRYLEYRNYDVLYVQNFTDIDDKVINRAREEHQAPLVIAERYIEEFFKDADALNVKRATLYPRVSQHIDAIIAAIATLVERGFAYVADGDVYFEVEKFPAYGRLSKRTPGEMRAGARVEVNTSKRNPLDFALWKAACPGEPSWESPWGPGRPGWHIECSTMALKYLGPGFDIHGGGADLIFPHHENEIAQAEAQTGCTFARFWLHNGFITVNQEKMSKSKGNFFLVRDILKRFRPLAVRLYLLATHYRSPIDFDDAGLLAAERGLERLENTRRLLGEARCQLTGTGAETTVPARTSALAGRAEELRQEFISAMDDDFNTARALAALYDLAREINSYLNGTTTIDPAALRTAAITFEQLGGEVLGLFGQARQQVDDELLSGLMDLILQVRQEARQRRDWATADTIRDRLKELGIVLEDTPRGPRWKRS
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRC_RHIME
Sequence: MNGQTPTDGGILYDATETDDEDDLVEVTEAERPAPAIGWAESLPEAAGLKGAELIQAFVKRLPNGPGVYRMLNEAGDVLYVGKARSLKKRVSNYAQGRGHSNRIARMVRETAHMEFVTTRTEIEALLLEANLIKRLRPRFNVLLRDDKSFPYIVVTGDTRAPALYKHRGARSRKGDYFGPFASAGAVGRTINSLQRAFLLRTCTDSVFETRTRPCLLYQIKRCSAPCTNEVSDADYAELVSEAKDFLSGKSQAVKATIASAMAEASENLDFERAALYRDRLAALSHVQSHQGINPAGVEEADVFATHHEGGISCIQVFFFRTGQNWGNRAYFPKADPSIPPAEVLSAFLAQFYDDKPCPRQVLLCAPVEEQELLAQALSEKSGYKVSILVPQRGEKKDLVEHALANAREAHGRKLAETASQGRLLEGFAATFQLPYVPRRIEIYDNSHIMGTNAVGGMVVAGPEGFVKGQYRKFNIKSTDITPGDDFGMMREVMTRRFSRLLKEEGKPDRSAEPGEDAGFPAWPDVILIDGGQGQMTAVRTILKELGIEDCVTAIGVAKGVDRDAGRERFFAEGRESFTLPPRDPVLYFIQRLRDEAHRFAIGSHRARRKKEMVKNPLDEIAGIGPTRKRALLTHFGTAKAVSRAGINDLMSVNGISETVARIVYEHFHEDAAK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BAC2_ARATH
Sequence: MDFWPEFMATSWGREFVAGGFGGVAGIISGYPLDTLRIRQQQSSKSGSAFSILRRMLAIEGPSSLYRGMAAPLASVTFQNAMVFQIYAIFSRSFDSSVPLVEPPSYRGVALGGVATGAVQSLLLTPVELIKIRLQLQQTKSGPITLAKSILRRQGLQGLYRGLTITVLRDAPAHGLYFWTYEYVRERLHPGCRKTGQENLRTMLVAGGLAGVASWVACYPLDVVKTRLQQGHGAYEGIADCFRKSVKQEGYTVLWRGLGTAVARAFVVNGAIFAAYEVALRCLFNQSPSPDIVTGD
What is the function of this protein?
Mitochondrial arginine transporter that catalyzes the counter-exchange of arginine with lysine, ornithine, arginine, histidine and citrulline.  Substrate preference in reconstituted proteoliposomes is arginine > homoarginine > citrulline > histidine > lysine > ornithine.  May be involved in the delivery of arginine, released from seed reserves, to mitochondrial arginase and the export of ornithine.  May contribute to proline accumulation in response to hyperosmotic stress.
What are the official names of this protein?
Mitochondrial arginine transporter BAC2, Mitochondrial basic amino acid carrier 2, AtMBAC2.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PROA_STRPS
Sequence: MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEILAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLENGLVITKKRVAIGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTALKKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPVIETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQMLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVAHIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQKLHARGPMGLKELTSYKYVVAGDGQIRE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RARR2_PONAB
Sequence: MRRLLIPLALWLGAVGVGVAELTEAQRRGLQVALEEFHKHPPVQWAFQETSVESAVDTPFPAGIFVRLEFKLQQTSCRKRDWKKPECKVRPNGRKRKCLACIKLGSEDKVLGRLVHCPIETQVLREPEEHQETQCIRVQRAGEDPHSFYFPGQFAFSKALPRS
What is the function of this protein?
Adipocyte-secreted protein (adipokine) that regulates adipogenesis, metabolism and inflammation through activation of the chemokine-like receptor 1 (CMKLR1).  Acts also as a ligand for CMKLR2.  Can also bind to C-C chemokine receptor-like 2 (CCRL2), but with a lower affinity than it does to CMKLR1 or CMKLR2.  Positively regulates adipocyte differentiation, modulates the expression of adipocyte genes involved in lipid and glucose metabolism and might play a role in angiogenesis, a process essential for the expansion of white adipose tissue.  Also acts as a pro-inflammatory adipokine, causing an increase in secretion of pro-inflammatory and prodiabetic adipokines, which further impair adipose tissue metabolic function and have negative systemic effects including impaired insulin sensitivity, altered glucose and lipid metabolism, and a decrease in vascular function in other tissues.  Can have both pro- and anti-inflammatory properties depending on the modality of enzymatic cleavage by different classes of proteases.  Acts as a chemotactic factor for leukocyte populations expressing CMKLR1, particularly immature plasmacytoid dendritic cells, but also immature myeloid DCs, macrophages and natural killer cells.  Exerts an anti-inflammatory role by preventing TNF/TNFA-induced VCAM1 expression and monocytes adhesion in vascular endothelial cells.  The effect is mediated via inhibiting activation of NF-kappa-B and CRK/p38 through stimulation of AKT1/NOS3 signaling and nitric oxide production.  Exhibits an antimicrobial function in the skin (By similarity).
What are the official names of this protein?
Retinoic acid receptor responder protein 2, Chemerin.
What are the subcellular locations of this protein?
Secreted.