PharMolix/UniProtQA huggingface dataset:
Protein: COBD_YERE8
Sequence: MTLSAWFVAFLLDHWLGDPPRWPHPVRWMGNLITLLQRAIRTLCHSEWALKWGGAVLWLLVVGITWLVSWGFLWLMTEINPWLGWLAQVWMIYTLLAGRCLSDAALAVFDALQHGTLAQSREKLSWIVGRDTSQLEKPQITRAVVETVAENSVDGVIAPLFFLMLGGAPLAMAYKAVNTLDSMVGYKTPKYRAIGYMSARMDDLANWLPARLSWVLLSAAAWLIQADYRQALRIGWRDRYQHSSPNCAWSEATVAGALGIRLGGPNDYCGERVEKPWIGDERREVALSDIPRSIHLMMMASLLALLLFALTHLLLVGI
What is the function of this protein?
Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
What are the official names of this protein?
Cobalamin biosynthesis protein CobD.
What is the protein family that this protein belongs to?
Belongs to the CobD/CbiB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GLMU_METVS
Sequence: MDAVILCAGSGTRLYPITENRPKPMIPIAGKPILEHIIEKIENHVEKIYLVVGFEKEKIIDYFYGNEKIEFIVQEKQLGTGHAVLMAKNYIKGDFLVLNGDVIFESDILEFLNYENAVGLSKVDNPENFGVIELGYDNKVINLLEKPNEDEIKSKFTSNLINAGIYKLENFVFEILENLLPSERGEIELTDALKKLIESSKLYGIELNGYWNDIGRPWDVLSANNYFLKNIMPKISGNIENNVTITGNVIIEEGVTVKSNSVIEGPVIIKSGAFIGPLAYIRPNTVLMEDTFVGNSSEIKGSIIMKNTKIPHLSYVGDSIIGSDCNFGCNTITANLRFDDEPVTLNIKGTKVKSVRKFGAVIGDNVKTGIQVSLMPGVKVGSNSIIGANCLVDKDIEKESFVYKKDELIIKKRN
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetyl-glucosamine (UDP-GlcNAc).  Responsible for the acetylation of GlcN-1-P to GlcNAc-1-P, and for the uridyl transfer from UTP to GlcNAc-1-P, to produce UDP-GlcNAc and pyrophosphate (By similarity).
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
Protein: PYRD_XANCB
Sequence: MYSLARPFLFAFDAERAHALALRAIDTAYRTGTTALVATRPVPLPTPAFGLMFPNPVGLGAGLDKNGEHIDALLALGFGFVEIGTVTPKPQEGNPKPRMFRLPEYQAVINRMGFNNLGVDVLVKNVQRARRRGGLLGINIGKNKDTPNEEATSDYRYCMERVYPLADYITVNISSPNTAGLRELQEEQALRRLIADLRETQEALAAQHGKRVPMLVKVAPDLNDRDIDAAARVLADLAVDGVIATNTTVTRTLVASHPMAEQAGGLSGAPLLGQSTLVLRRLRARLPESIPLIGVGGITSGADAVAKMAAGASLVQCYSGLVYRGPRLIGECVDAIRRRRESPSGGAVGPL
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RNC_BORAP
Sequence: MKKNSSDFCFSNERKAQLSEFLENLSIDFNNFDLLNTALSHSSYSNELDQKSDNNERLEFLGDSVLNLIITDHLYKTYPNKSEGELSKARSYIVSEDSLSSIAREIDLGSYILLGRGEESNDGRNKKGILADAIEAFVGAIYLDSGFLIATEFVVGLFDMYIRLMFNRGDFKDYKSLLQEYVQKKYKISPNYKLDKEIGPDHDKVFCVELYVGEKFISNGKGKSKKEAEMRAAEVALKAMEDINL
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACM2_RAT
Sequence: MNNSTNSSNNGLAITSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKEKKEPVANQDPVSPSLVQGRIVKPNNNNMPGGDGGLEHNKIQNGKAPRDGVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENTVSTSLGHSRDDNSKQTCIKIVTKAQKGDVCTPTSTTVELVGSSGQNGDEKQNIVARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
What is the function of this protein?
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.  Primary transducing effect is adenylate cyclase inhibition.  Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol (By similarity).
What are the official names of this protein?
Muscarinic acetylcholine receptor M2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM2 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi- pass membrane protein. Note=Phosphorylation in response to agonist binding promotes receptor internalization.
Protein: RECO_PARMW
Sequence: MAERTLVGLALKVGPLGEHDRLLSLLSDAEGVTRLAVPGARRPKSSLAAAAPLTLLELQVGGRSGLARVRQLRVLHSHAGLGRQLETLSAAQAFCDLCLQIGREDPVEGLLATLQLHLERLDQRSDCLDELLASSVQGAIHLLTLGGYSLPLQSCCLSGAPLEPPIGTWEWRCSLLPMDGFAIDRQPGAAMTLNPSELALLQRLTRADLPRRRDGELMGPRPVWLRLLAVVEIWIRTHLQRGNPALAMLRECVTAKQVSQHGADAANS
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: SYI_HELHP
Sequence: MDYKETLILPDTSFPMRGNLPANEPHTYAKWRDEKLYSKLKNAHSGAKNFCLHDGPPYANGHLHIGHALNKILKDIIVKYHYFKGENIRYTPGWDCHGLPIEQQVEQKIGKAKKDNLNKTKLRELCRNHAQKFIQIQSDEFQALGVLGDFENPYKTMDFAFEAQIYRSLIELVKEGLLAERSKPIYWSWACETALADAEVEYQDKQSDSIFVAFTLSDSALQSLGISQGKVIIWTTTPWTLPANVGIALNPSESYVLTDKGYIVAKALLEKVCENIDIGISKREFKAQEFERLEAINPLNGRTSLIVLGEHVSINDGTGAVHTAPGHGEDDYYIGLKYGLEVIMPVDDRGNFSPLIESMGLVPKEFANEFVGKNIFDTHESIFKILGKALLKQDVITHSYPHCWRSHKPVIYRATAQWFILLDKPFYQGKTLKELALEELDKVRFYPQNGKNRIYSMIENRPDWCISRQRDWGVPIAFLIDKITNVALLDEAVLEHIACIFEKEGCDAWWSYEIKDLLPPSHKHLAENLTKSKHILDVWFDSGSTWSAVLENEYKGAGNNYDAGSHPADMYLEGSDQHRGWFQSSLLLSCAIAKRAPYKQILTHGFTFDRNGEKMSKSKGNVISPSEIIKTQGSEILRLWVALSHYQSDQNISDEILKQVGEQYRKIRNTIRFLLANASQNSQDMVEKDELDVIDRWILSVCDRVFDEAYEYFDEYEFAKAFQVVMSFLINELSGIYLDLCKDILYCDDVSSLRRRAIQSALVMILRRVLHFIAPVLTYTADEAFRHSSAALKGEYESIFDLPKLSCAQGYNLEINEDFTRLLRVREKFTESLDNLKKQKIVKSSLEVLLQSPQEKEFALLDRWLIVSGVCGKECKDKEELARFMLEDKEEFVIYRAQNGRCERCWQFIVEESEGKLCKRCTSVIAQTKK
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE_DESVH
Sequence: MSNVVTRFAPSPTGHLHIGGARTAIFNWLLARHFGGRFVLRIEDTDTERSKQEYTDSILASMKWLGLDWDGDLIYQSERFDIYNSYIDRLLESGHAYWCECPPDEVEKMREEARAKGLKPRYNGRCRSRDLGPGDGRVVRLKAPAEGRIVFDDLVKGTVAFDVAELDDMVLRRSDGAPTYNLAVVVDDATMGVTHVLRGDDHLSNTPKQILLYQALGFDLPRFGHVPMILGPDRKKLSKRHGAKAVIEYEQYGLLPQALVNYLVRLGWSHGDQEIFALEELVEKFGTENLNSSAAGFDPDKLEWLNGHYLRETSPEELARLVLPFVAAEGFDVDASRLAQLVPLFRERANNLVELARVMRFMLVPAAEVEYDAAAVAKALTEEGRRHVAGVREALAALGTFDREGCEKAIHDYVEGNGLKFKQVAPAVRVAVVGAMGGPGLPDMMALLGRDDVLARLDRAVAL
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBA5_DROGR
Sequence: MSAAIDELQAIIAELKSELEEQKTTTRNARERIERMSAEVVDSNPYSRLMALQRMNIVKDYERIRDKAVAIVGVGGVGSVTADMLTRCGIGKLILFDYDKVELANMNRLFFTPDQAGLSKVEAAARTLSFINPDVCIETHNYNITTVDNFDQFLSTISASGIAVGQPVDLVLSCVDNFEARMAINAACNEKNMNWFESGVSENAVSGHIQFVRPGDTACFACAPPLVVAENIDERTLKREGVCAASLPTTMGITASLLVQNALKYLLNFGEVSDYLGYNALSDFFPKMTLRPNTQCDDRNCLVRQKEFHLRPKPVEKLVEVEVSDEPLHACNDWGIELVADNVPTTTTKSPENTNVAFGLRLAYEAPDKSEKSETTATAGDGVSEASLEELMAQMKSM
What is the function of this protein?
E1-like enzyme which activates UFM1.
What are the official names of this protein?
Ubiquitin-like modifier-activating enzyme 5, Ubiquitin-activating enzyme 5.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-activating E1 family. UBA5 subfamily.
Protein: AB17A_RAT
Sequence: MNGLSVSELCCLFCCPPCPGRIAAKLAFLPPEPTYSLVPEPEPGPGGAGAAPSGPLRTSAATPGRWKIHLTERADFQYGQRELDTIEVFVTKSARANRIACMYVRCVPGARYTVLFSHGNAVDLGQMCSFYVGLGTRIGCNIFSYDYSGYGISSGRPSEKNLYADIDAAWQALRTRYGISPDSIILYGQSIGTVPTVDLASRYECAAVVLHSPLTSGMRVAFPDTKKTYCFDAFPNIEKVSKITSPVLIIHGTEDEVIDFSHGLALYERCPKAVEPLWVEGAGHNDIELYSQYLERLRRFISQELPSQRT
What is the function of this protein?
Hydrolyzes fatty acids from S-acylated cysteine residues in proteins (PubMed:27307232).  Has depalmitoylating activity towards NRAS (By similarity).  Has depalmitoylating activity towards DLG4/PSD95 (PubMed:27307232).  May have depalmitoylating activity towards MAP6 (PubMed:28521134).
What are the official names of this protein?
Alpha/beta hydrolase domain-containing protein 17A, Abhydrolase domain-containing protein 17A.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. ABHD17 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Recycling endosome membrane; Lipid-anchor; Cytoplasmic side. Cell projection, dendritic spine. Postsynaptic density membrane.
Protein: PSBD_DAUCA
Sequence: MTIALGKFTKDEKDLFDIMDDWLRRDRFVFVGWSGLLLFPCAYFAVGGWFTGTTFVTSWYTHGLASSYLEGCNFLTAAVSTPANSLAHSLLLLWGPEAQGDFTRWCQLGGLWTFVALHGAFGLIGFMLRQFELARSVQLRPYNAIAFSGPIAVFVSVFLIYPLGQSGWFFAPSFGVAAIFRFILFFQGFHNWTLNPFHMMGVAGVLGAALLCAIHGATVENTLFEDGDGANTFRAFNPTQAEETYSMVTANRFWSQIFGVAFSNKRWLHFFMLFVPVTGLWMSALGVVGLALNLRAYDFVSQEIRAAEDPEFETFYTKNILLNEGIRAWMAAQDQPHENLIFPEEVLPRGNAL
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.  D2 is needed for assembly of a stable PSII complex.
What are the official names of this protein?
Photosystem II D2 protein, PSII D2 protein, Photosystem Q(A) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: NFE2_BOVIN
Sequence: MSPCPPQQSRNRVTQLPIPEPGEMELTWQEIMSITELQGLNAPSEPSFEPPAPVPYPGPPPPPSYCPCSIHSEPGFPLPAPPYELPAPTSHVPDPPYSYGSNMTVPVSKPLTLSGLLSDPLPDPLALLDIGLSAGPSKPQEDPESDSGLSLNYSDAESLELEGTEAGRRRSEYVEMYPVEYPYSLMPNSLTHPNYALPPAETPLALEPSSGPVRAKPTARGEAGSRDERRALAMKIPFPTDKIVNLPVDDFNELLARYPLTESQLALVRDIRRRGKNKVAAQNCRKRKLETIVQLERELERLGSERERLLRARGEADRTLEVMRQQLTDLYRDIFQHLRDEAGNSYSPEDYALHQAADGAIFLVPRGTKMEATD
What is the function of this protein?
Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation.  Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR).  This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters.  Requires MAFK or other small MAF proteins for binding to the NF-E2 motif.  May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron (By similarity).
What are the official names of this protein?
Transcription factor NF-E2 45 kDa subunit, Leucine zipper protein NF-E2, Nuclear factor, erythroid-derived 2 45 kDa subunit, p45 NF-E2.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. CNC subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=The sumoylated form locates to the nuclear bodies PML oncogenic domains (PODs). Translocated to the cytoplasm through interaction with ITCH.
Protein: CDP1_ARATH
Sequence: MPVAYTFPVLPSSCLLCGISNRSTSFVVDRPELQISGLLVVRSESGEFFGSGLSLRRFQREGRRRLNAAGGGIHVVDNAPSRTSSLAASTSTIELPVTCYQLIGVSEQAEKDEVVKSVINLKKTDAEEGYTMEAAAARQDLLMDVRDKLLFESEYAGNLKEKIAPKSPLRIPWAWLPGALCLLQEVGQEKLVLDIGRAALRNLDSKPYIHDIFLSMALAECAIAKAAFEVNKVSQGFEALARAQSFLKSKVTLGKLALLTQIEESLEELAPPCTLDLLGLPRTPENAERRRGAIAALRELLRQGLSVEASCQIQDWPCFLSQAISRLLATEIVDLLPWDDLAITRKNKKSLESHNQRVVIDFNCFYMVLLGHIAVGFSGKQNETINKAKTICECLIASEGVDLKFEEAFCSFLLKQGSEAEALEKLKQLESNSDSAVRNSILGKESRSTSATPSLEAWLMESVLANFPDTRGCSPSLANFFRAEKKYPENKKMGSPSIMNHKTNQRPLSTTQFVNSSQHLYTAVEQLTPTDLQSPVVSAKNNDETSASMPSVQLKRNLGVHKNKIWDEWLSQSSLIGRVSVVALLGCTVFFSLKLSGIRSGRLQSMPISVSARPHSESDSFLWKTESGNFRKNLDSVNRNGIVGNIKVLIDMLKMHCGEHPDALYLKSSGQSATSLSHSASELHKRPMDTEEAEELVRQWENVKAEALGPTHQVYSLSEVLDESMLVQWQTLAQTAEAKSCYWRFVLLHLEVLQAHIFEDGIAGEAAEIEALLEEAAELVDESQPKNAKYYSTYKIRYILKKQEDGLWKFCQSDIQIQK
What is the function of this protein?
Component of the plastid division machinery required for PDV1 localization to constriction sites.  Involved in chloroplast division site placement (PubMed:28984364, PubMed:23936263).  Required for the proper formation of FtsZ rings at the division site in nongreen plastids (e. g.  etioplasts) (PubMed:23936263).  Inhibits FtsZ assembly, functioning as an antagonistic regulator of FtsZ dynamics against ARC6, by recruiting ARC3 to the middle of the plastid to facilitates its interaction with FtsZ proteins (PubMed:26527658, PubMed:30824505).  Required during stromule biogenesis in the leaf epidermis, especially in non-mesophyll cells plastids (PubMed:28984364).
What are the official names of this protein?
Plastid division protein CDP1, chloroplastic, ARC6-homolog protein, Protein CHLOROPLAST DIVISION SITE POSITIONING 1, AtCDP1, Protein PARALOG OF ARC6, Protein STROMULE BIOGENESIS ALTERED 2.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Single-pass membrane protein. Note=Localizes both to the mid-plastid and to a single spot at one pole.
Protein: RL35_SALCH
Sequence: MPKIKTVRGAAKRFKKTGKGGFKHKHANLRHILTKKATKRKRHLRPKAMVSKGDLGLVIACLPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: TUSA_SHELP
Sequence: MSDPFAQAQHQLDALGLRCPEPVMMVRKSVRKMNEGETLLIIADDPATTRDIPSFCEFMDHTLIASQTESTPYQYLIKKGL
What is the function of this protein?
Sulfur carrier protein which probably makes part of a sulfur-relay system.
What are the official names of this protein?
Sulfur carrier protein TusA.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXK_RHOCS
Sequence: MKAPAFWYAPPGTARPLLSALLTPAALAWTAATRRRLSGTRPWHAPVPVICVGNLVAGGAGKTPVVLDLLSRLRRGGLDAHALSRGHGGRLPGPLRVDPARHTAAEVGDEPLLLAAAAPAWIARDRAAGARAAADAGAGVLVLDDGFQNPGIAKDLSLLVVDGDAGFGNGRVIPAGPLREPVADGLARAQAVLLLGEDRRGTADLCRGRLPVLRGRLVPDPQAAADLEGRRVLAFAGIGRPEKLFRTLEALGADVVARLPFPDHHPFTAAELRALLDRAAALDALPVTTQKDLVRLPAELRGQVRALPVSIAWEEPDTLDRLLAPLLSGKDDHGQAQ
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: RL25_BURL3
Sequence: MKVVAFERQEQGTGASRRLRNAGKTTGIVYGGEAAPQKIELDHNALWHALKKEAFHSSILDLEVAGQSQQVLLRDVQYHPFKQLVLHVDFQRVDAKKKLHTKAPLHFLNAEISPAVKLSSAIVSHVATEIEIECLPADLPEFLEVDLSKIEAGQSLHAKDITLPKGVVLVAHVDAENPVVASATVPAGAVSDAAEGETPAA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: RUVA_PROA2
Sequence: MYAYFRGELISSSRDNAIVDVGGVAYRLLISNSTYRQLPSSGDQVKLLAHLHVKEDLMQLYGFIEEEERQLFLLLLSISGVGPKLALAILSGLPVEEIQEAIMANKPETLFGISGVGKKTAARIILELRDRILKLQQTRPGKTAGAGSVASLSEDALQALMTLGFSRASAQQAVTRALLSAENPGVEDIVREALQNIRNH
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: PSAK_NEOYE
Sequence: MNILFVLSSVPHTSPWSTQVAMVMITCNLLAIVAGRYAIKVRGLGPSIPVSGVEGFGLPELLATTSLGHVIGAASILGLSNVGLIS
What are the official names of this protein?
Photosystem I reaction center subunit PsaK, PSI-K, Photosystem I subunit X.
What is the protein family that this protein belongs to?
Belongs to the PsaG/PsaK family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CLN5C_DICDI
Sequence: MKNMLNIILTLTIIFIGLIKISISSDSGSSENGIYFYTYDTICEFTNSIRDDDQYELYYVQAPLMYAIYGDLFEKINAYHSGVGFYNLNGGPNISIDYFAGPTLEDALIPQNITKDSQGNYNLTWNTYGLIEVTNYINETYWSKRELIMYGLTGLQVKQYLSWAPIYNQTHPVYNLFSIASADASGSGDNGYLETILHNLGIGGGGGGSGSENLIVYQNSSTCDDFVWASFNTIYQLGGTLVGMQSNPPKDQITLFTTDEPTIVDYNNITQRNQLASFYINLMGIANKNESALQIFQELISLFNGTFYCYIDGVYYELHLSKPTPISFTYQPSPMPTGQRNSNSIETLNNCYSKSSTDNQSFFNRFSKIQIIFISIAIGFGVVIILYISIGIMVNKSRGKSGTNLIPNKKLWTSIGSKFKRDNNKNNYKPLLYNENTIQ
What are the official names of this protein?
Cln5-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the CLN5 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SOMA_RABIT
Sequence: MAAGSWTAGLLAFALLCLPWPQEASAFPAMPLSSLFANAVLRAQHLHQLAADTYKEFERAYIPEGQRYSIQNAQAAFCFSETIPAPTGKDEAQQRSDMELLRFSLLLIQSWLGPVQFLSRAFTNTLVFGTSDRVYEKLKDLEEGIQALMRELEDGSPRVGQLLKQTYDKFDTNLRGDDALLKNYGLLSCFKKDLHKAETYLRVMKCRRFVESSCVF
What is the function of this protein?
Plays an important role in growth control.  Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1.  It stimulates both the differentiation and proliferation of myoblasts.  It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
What are the official names of this protein?
Somatotropin, Growth hormone.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: BIOF_VIBC1
Sequence: MPAFKSRIESALADRKAQGLNRSINVVFSGNQSILECEGRRYINFSSNDYLGLANDQALVRAWQQGLSVYGSGSGASPMVTGFSAAHSNLEAALTEWLGYERAILFGSGFSANQALLLTLLEKSDVLIQDRLNHASLMEAGMLSPAKMKRFKHNDIAHLNSLLSSEDNHLVVTEGVFSMDGDCAPLADIAEVTSSHDAWFAVDDAHGIGVLGESGGGSCELAKVKPELLIVTFGKAFGMSGAAILCDHATGDFLTQFARHHVYSTAIPPAQAYALTHAVSMIQEQSWRREKLTELNEAYRDGLQDLDGFVETQTSIKPFMIGESELALQVASACRQNGIWVTAIRPPTVPKGTSRLRITLTANHTNEQIKTLSMALKQALGAL
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: NADD_PETMO
Sequence: MLMLFGGSFNPPHIGHRIIAEIAYDEFNPDRFLIVPSKNPPHKSIDFIANFDKRYSWCERVFFEHYFEVSDIENKLPSPSYTIRTIEYLSNFDKNINLLIGEDSLKNFHKWYKWEEILKKVKLVVYPRYFEEKNSYSVDFDYVKLESPIVEISSTYIRQRIKKGKTVKGLIDDKIFEEVLKEYS
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: PRS29_MOUSE
Sequence: MLIQLCLTLFFLGCSIAGTPAPGPEDVLMGIVGGHSAPQGKWPWQVSLRIYRYYWAFWVHNCGGSIIHPQWVLTAAHCIRERDADPSVFRIRVGEAYLYGGKELLSVSRVIIHPDFVHAGLGSDVALLQLAVSVQSFPNVKPVKLPSESLEVTKKDVCWVTGWGAVSTHRSLPPPYRLQQVQVKIIDNSLCEEMYHNATRHRNRGQKLILKDMLCAGNQGQDSCYGDSGGPLVCNVTGSWTLVGVVSWGYGCALRDFPGVYARVQSFLPWITQQMQRFS
What is the function of this protein?
Involved in embryo hatching and implantation.
What are the official names of this protein?
Serine protease 29, Implantation serine proteinase 2, ISP-2, Strypsin-2, Strypsin-related protein, Tryptase-like proteinase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
Protein: VE4_CRPVK
Sequence: MSHGHCRIPVEKGSKALRKRHSKRTQLLLRFTMMVTEGTTMNTHCGVYLLLGTLMGSGLRLKVEWTIEGFIMWTLKETMCIMWTSQPTRDVLLLMDTMTWCFKTCASLLLSPAPPSRWSVPLKTPSPKRPPTVQCPPLKRKQGPKPRVHWADEGQGHQGCNEGRQSNENRPPRTKRILLPGTSDRLLQRTLDEELRRLEEHLPGGIDGFASL
What are the official names of this protein?
Probable protein E4.
Protein: MDTB_SALSV
Sequence: MQVLPPGSTGGPSRLFILRPVATTLLMAAILLAGIIGYRFLPVAALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQSSGGASVVTLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPIYSKVNPADPPIMTLAVTSNAMPMTQVEDMVETRVAQKISQVSGVGLVTLAGGQRPAVRVKLNAQAVAALGLTSETVRTAITGANVNSAKGSLDGPERAVTLSANDQMQSADDYRRLIIAYQNGAPVRLGDVATVEQGAENSWLGAWANQAPANVMNVQRQPGANIIATADSIRQMLPQLTESLPKSVKVTVLSDRTTNIRASVRDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAVTLAVAILISAVVSLTLTPMMCARMLSQQSLRKQNRFSRACERMFDRVIASYGRGLAKVLNHPWLTLSVAFATLLLSVMLWIVIPKGFFPVQDNGIIQGTLQAPQSSSYASMAQRQRQVAERILQDPAVQSLTTFVGVDGANPTLNSARLQINLKPLDARDDRVQQVISRLQTAVATIPGVALYLQPTQDLTIDTQVSRTQYQFTLQATTLDALSHWVPKLQNALQSLPQLSEVSSDWQDRGLAAWVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTASTPGLAALETIRLTSRDGGTVPLSAIARIEQRFAPLSINHLDQFPVTTFSFNVPEGYSLGDAVQAILDTEKTLALPADITTQFQGSTLAFQAALGSTVWLIVAAVVAMYIVLGVLYESFIHPITILSTLPTAGVGALLALIIAGSELDIIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPRDAIFQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGIAMVGGLLVSQVLTLFTTPVIYLLFDRLSLYVKSRFPRHKEEA
What are the official names of this protein?
Multidrug resistance protein MdtB, Multidrug transporter MdtB.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.