PharMolix/UniProtQA huggingface dataset:
Protein: TTUA_THET2
Sequence: MVCKVCGQKAQVEMRSRGLALCREHYLDWFVKETERAIRRHRMLLPGERVLVAVSGGKDSLALWDVLSRLGYQAVGLHIELGIGEYSKRSLEVTQAFARERGLELLVVDLKEAYGFGVPELARLSGRVACSACGLSKRYIINQVAVEEGFRVVATGHNLDDEAAVLFGNLLNPQEETLSRQGPVLPEKPGLAARVKPFYRFSEREVLSYTLLRGIRYLHEECPNAKGAKSLLYKEALNLVERSMPGAKLRFLDGFLEKIRPRLDVGEEVALRECERCGYPTTGAVCAFCRMWDAVYRRAKKRKLLPEEVSFRPRVKPLRAG
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of 5-methyluridine residue at position 54 in the T loop of tRNAs, leading to 5-methyl-2-thiouridine (m(5)s(2)U or s(2)T) (PubMed:16547008, PubMed:28439027).  This modification allows thermal stabilization of tRNAs in thermophilic microorganisms, and is required for cell growth at high temperatures (PubMed:16547008).  TtuA transfers the S atom from the thiocarboxylated C-terminus of TtuB to tRNA (PubMed:28439027).
What are the official names of this protein?
tRNA-5-methyluridine(54) 2-sulfurtransferase, 2-thiouridine synthetase TtuA, tRNA two-thiouridine-synthesizing protein A.
What is the protein family that this protein belongs to?
Belongs to the TtcA family. TtuA subfamily.
Protein: LAMB_CROS8
Sequence: MMITLRKLPLAVAVMAGIFAAQASAVDFKGYARSGIGWTGSGGEQQCFQATGAGAKYRLGNECETYAELKLGQEVWKEGDKSFYFDTNVAYSVAQQNDWEATSPAFREANVQGKNLIDALPGSTIWAGKRFYQRHDVHMIDFYYWDISGPGAGIENVDLGFGKLSVAATRSSEAGGSATFQSDSIYDYNKSTANDVFDVRLGSLEVNPGGTLELGVDYGRANARDDYYLADDATKDGWMFTAEHVQTIGTGFNKFVVQYATDALTSQGKGLSQGSGIGISDTDPKFAYAQNNNGHMLRLIDHGSISMGDRWDMMYVGMYQDIDWDNNNGTRWWTVGVRPMFKWTPIMSTLLEVGYDNVKSQRTDETNNQYKITLAQQWQAGDSIWSRPALRVFATYAKWDEKWGYDKTGNPSNNANYGYAVKDGFNGGSFGRGDNDEWTFGAQMEIWW
What is the function of this protein?
Involved in the transport of maltose and maltodextrins.
What are the official names of this protein?
Maltoporin, Maltose-inducible porin.
What is the protein family that this protein belongs to?
Belongs to the porin LamB (TC 1.B.3) family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: HDAC4_RAT
Sequence: MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPAAVPMDLRLDHQFSLPLEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLAMKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVLNKKKALAHRNLNHCMSSDPRYWYGKTQHSSLDQSSPPQSGVSASYNHPVLGMYDAKDDFPLRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVATALKKRPLDVTDSACSSAPGSGPSSPNSSSGNVSTENGIAPTVPSTPAETSLAHRLVTREGSVAPLPLYTSPSLPNITLGLPATGPAAGAAGQQDAERLALPALQQRISLFPGTHLTPYLSTSPLERDGGAAHNPLLQHMVLLEQPPTQTPLVTGLGALPLHTQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNAQALQHLVIQQQHQQFLEKHKQQFQQQQLHLSKMISKPSEPPRQPESHPEETEEELREHQALLDEPYLDRLPGQKEPSLAGVQVKQEPIESEEEEVEATREAEPSQRPATEQELLFRQQALLLEQQRIHQLRNYQASMEAAGIPVSFGSHRPLSRAQSSPASATFPMSVQEPPTKPRFTTGLVYDTLMLKHQCTCGNTNSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVHSEAHTLLYGTNPLNRQKLDSSLTSVFVRLPCGGVGVDSDTIWNEVHSSGAARLAVGCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAIAAKLLQQRLNVSKILIVDWDVHHGNGTQQAFYNDPNVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFTGGLDPPMGDAEYLAAFRTVVMPIANEFAPDVVLVSSGFDAVEGHPTPLGGYNLSAKCFGYLTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELEPLPEKVLHQRPNANAVHSMEKVMGIHSEYWRCLQRLSPTVGHSLIEAQKCENEEAETVTAMASLSVGVKPAEKRSEEEPMEEEPPL
What is the function of this protein?
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4).  Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.  Histone deacetylases act via the formation of large multiprotein complexes.  Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.  Deacetylates HSPA1A and HSPA1B at 'Lys-77' leading to their preferential binding to co-chaperone STUB1.
What are the official names of this protein?
Histone deacetylase 4, HD4.
What is the protein family that this protein belongs to?
Belongs to the histone deacetylase family. HD type 2 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm. Upon muscle cells differentiation, it accumulates in the nuclei of myotubes, suggesting a positive role of nuclear HDAC4 in muscle differentiation. The export to cytoplasm depends on the interaction with a 14-3-3 chaperone protein and is due to its phosphorylation at Ser-245, Ser-466 and Ser-630 by CaMK4 and SIK1. The nuclear localization probably depends on sumoylation (By similarity). Interaction with SIK3 leads to HDAC4 retention in the cytoplasm (By similarity). Interacts with ZNF638 (By similarity).
Protein: Y1595_ALKCK
Sequence: MAQEEKERFVIPDENGTEHLFDELFRFTVDETEKSYMVLVPVGEEEDDEEEVEVFAFRYEEQQNEDNDISFYPVETDEEWDMIEEMLNTFSEEEE
What are the official names of this protein?
UPF0473 protein ABC1595.
What is the protein family that this protein belongs to?
Belongs to the UPF0473 family.
Protein: DPCKG_SULAC
Sequence: MPRSLRAELSKPYGVLFINENKLKQFLINKSNSRLITVGDVVTQTILKFHIKPFLAIVDGKTKRKLVKENFGQFEYIKVKNEPGLIRLSTIREIKDILVHNENDKILMVDGEEDLLVIPVVIYGNFGDIIIYGQPNAGVVVTLNNDFLKRRVLEIFKKFQVTSC
What is the function of this protein?
Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
What are the official names of this protein?
GTP-dependent dephospho-CoA kinase, Dephospho-coenzyme A kinase, DPCK.
What is the protein family that this protein belongs to?
Belongs to the GTP-dependent DPCK family.
Protein: M4H35_BOMMX
Sequence: MNFKYIFAVSFLIASAYARSVQNDEQSLSQRDVLEEESLREIRGIGGVLLSAGKAALKGLAKVLAEKYANGKRTAEEHEVMKRLEAVMRDLDSLDHPEEASERETRGFNQDEIAKEKRILGPVLGLVGNALGGLIKKIG
What is the function of this protein?
Maximin-H3 shows antibacterial activity against both Gram-positive and Gram-negative bacteria.  It shows also antimicrobial activity against the fungus C. albicans.  Shows strong hemolytic activity.
What are the official names of this protein?
Maximins 4/H3 type 5.
What is the protein family that this protein belongs to?
Belongs to the bombinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RIMP_BURVG
Sequence: MQLTELIETTVTGLGYELVDLERTGRGMLCIYIDQPAGISLDDCEKVTRQLQHVLTVENIDYERLEVSSPGLDRPLKKLADFERFAGSEVSVTLKKPLDGRKTYRGILHAPNGETIGLEFERNKGEAAMLDFTLADIDKARLIPQVDFRSRK
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMA_ECO8A
Sequence: MTPEHLPTEQYEAQLAEKVVRLQSMMAPFSDLVPEVFRSPVSHYRMRAEFRIWHDGDDLYHIIFDQQTKSRIRVDSFPAASELINQLMTAMIAGVRNNPVLRHKLFQIDYLTTLSNQAVVSLLYHKKLDDEWRQEAEALRDALRAQNLNVHLIGRATKTKIELDQDYIDERLPVAGKEMIYRQVENSFTQPNAAMNIQMLEWALDVTKGSKGDLLELYCGNGNFSLALARNFDRVLATEIAKPSVAAAQYNIAANHIDNVQIIRMAAEEFTQAMNGVREFNRLQGIDLKSYQCETIFVDPPRSGLDSETEKMVQAYPRILYISCNPETLCKNLETLSQTHKVERLALFDQFPYTHHMECGVLLTAK
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: RPOB_VIBVY
Sequence: MVYSYTEKKRIRKDFGTRPQVLDIPYLLSIQLDSFDKFIEQDPEGQYGLEAAFRSVFPIQSYNGNSELQYVSYRLGEPVFDVKECQIRGVTYSKPLRVKLRLVIFDKDAPAGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLYVRIDRRRKLPSTIILRALGKSTEEILDTFFEKVNFEVKDQTLMMELVPDRLRGETATFDIEANGTVYVEKGRRVTARHIRQLEKEGVDQIEVPVEYIVGKVSSKDYINEATGEIIVAANQEISLEALAKLSQAGHKQLEVLFTNDLDHGPFMSETLRIDSSVDRISALVEIYRMMRPGEPPTKEAAEALFESLFFSEERYDLSTVGRMKFNSSIGRDDAEEQGTLDETDIIEVMKKLIAIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDAVMPQDLINAKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHVTHYGRLCPIETPEGPNIGLINSLSAFARCNEYGFLETPYRRVVDGVVTDEVDYLSAIEEGQFVIAQANAKLNEDGTFADELITARQKGESGLHPREHVDYMDVATNQVVSIAASLIPFLEHDDANRALMGANMQRQAVPTLKAEKPLVGTGIERNVAVDSGVTSVAKRGGIIQSVDASRIVVKVNEEELIPGEAGIDIYNLTKYTRSNQNTCINQRPCVMPGEPVLRGDVLADGPSTDLGELALGQNMRIAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELTCVARDTKLGSEEITADIPNVGESALSKLDESGIVYIGAEVKGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVPNSVSGTIIDVQVFTRDGVEKDKRALEIEQMQLKEAKKDLTEEFQILEGGLLNRVKAVLLSGGYSEAKLDTTDRKKWLELTLEDDALQTQLEQLAEQYDELKADFDKKFETKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPVEDMPYDEKGQPVDIVLNPLGVPSRMNIGQILEVHLGLAAKGIGDKINQMVKEQQELAKFREFLQKVYDLGETRQKVDIASLSDEEVRTLIGNLRGGLPIATPVFDGASEASIKELLKLGGLPESGQLTLFDGRTGDAFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHAMEPGMPESFNVLLKEIRSLGINIELEDEQ
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: MIAB_SHEFN
Sequence: MSKKLHIKTWGCQMNEYDSSKMADLLDDYQGYTLTEDASEADVLLLNTCSIREKAQEKVFHQLGRWKSLKDKNPNLIIGVGGCVASQEGKAIKDRAQCVDIIFGPQTLHRLPEMIEQIQRGEKAVIDISFPEIEKFDRLPEPRADGPTAFVSIMEGCSKYCSFCVVPYTRGEEVSRPLDDVILEVAQLAAQGVREVNLLGQNVNAYRGATHDDEICTFAELLRLVASIDGIDRLRFTTSHPIEFTQDIIDVYEDTPELVSFLHLPVQSGSDRILTQMKRGHMAIEYKSIIRRLRKARPDIQISSDFIIGFPGESKDDFADTMKLIEDVAFDHSFSFIYSARPGTPAADLPDDVSDEEKKQRLAILQDRITQQAMRYSRQMLGTVQRILVEGPSVKNPMELRGRTENSRVVNFEAAHTHIGSFVDVKIVDVYTNSLRGEFVRGENEMDLRRSLRPAEILAKHKQDDALGVTHFKP
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIP3_ARTBC
Sequence: MWSLLTAAVLFARLSIAVPTTAAPAIEKRAAPTVQLDYATVVGSSALGIDSFKGIPYAQPPVGKLRLKPPQPITGDLGTVQATGLPRACPQMYLKSDDIPDDILGRFINTPVFQKITHAGEDCLTINVQKPSSATPESKLPVLFWIFGGGFEFGSTQLYDGTSLILRSMAQNRDIIFVAVNYRVGGFGFLPGADIKKDGSANLGLLDQRLGLQWVAENIEKFGGDPEKVTIWGESAGAISVFDQMALYDGDNTYKGKPLFRGAIMNSGSVIPADPVDCPKGEVVYEKVVEEAGCSKATDKLDCLRSVDYTTFLNAANSVPGILSYNSVALSYLPRPDGKALTASPDKLGRSGLLAKVPLIIGDQEDEGTLFSLVQNNITTTEHLVDYFSTYFFHGATKEQLRALVDTYPNDPSAGSPFRTGNLNQLYPQYKRLAAMLGDLVFTLSRRVFLDIANSKFPEIPTYSYLGTYGHIIPILGTSHGSDVLTSFGYTPGIPSTSIQNYYLSFVNNLDPNKGTPLGFPKWPRWSEGKMLLNFEAVKNSLLKDDFRGESAKYLEEHTDILHI
What are the official names of this protein?
Probable secreted lipase ARB_02369.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: KIAS1_HUMAN
Sequence: MGDIFKNNGVLQGRLRAVACAPHCFGPRLRCLHHDQGLTELAWGTWPHSHPVRHQPQMPSARECCSIVCMAAKEVSAPKAPGSPWMVPGDVAMSGHRVGALDERGHPNPQTGHCRGGSVSVTWSSVSCCRGRLAAVRVMIARDPSTCHLAKGCSPAWGFLPQARGPAGTRTPQRRCSSHEA
What are the official names of this protein?
Putative uncharacterized protein KIF25-AS1, KIF25 antisense RNA 1, KIF25 antisense gene protein 1, Protein HGC6.1.
Protein: CRCB_SALTI
Sequence: MLQLLLAVFIGGGTGSVARWMLSMRFNPLHQAIPIGTLTANLLGAFIIGMGFAWFNRMTHIDPMWKVLITTGFCGGLTTFSTFSAEVVFLLQEGRFGWALLNVLINLLGSFAMTALAFWLFSAAAAR
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RPOA_RICPU
Sequence: MLSLSKNWNTLIKPNKVAYENFPETNNKAKIVVEPLERGFGLTLGNAMRRVLLSSLQGAAITSIKIPAIEHEFSSIPGVKEDVSEVILNIKGIEVKMHVAEKRIMKLKATGPCVVKAGMIETGHDVEILNPDHVICDLAKDKQLEMELTCKVGKGYVLSTNSYEDNLPIGEIAIDALFNPVKSVTYKVENTRVGQVTDYDKLIMFVETNGDVLPEMAVGLAARILQEQLQLFISFEEQEEDKQVKTDALPFAPYLLKRVDELELSVRSANCLKNDNIIYIGDLVKRTESDMLRTPNFGRKSLNEIKEILAKFNLRFGMDVPDWPPENIQELSKRYEDSYN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: SUCC_PSEA8
Sequence: MNLHEYQGKQLFAEYGLPVSKGFAVDTPEEAAEACDKIGGSEWVVKAQVHAGGRGKAGGVKLVKSKEDAKAFAQQWLGKNLVTYQTDANGQPVSKILVESCTDIDKELYLGAVVDRSSRRIVFMASTEGGVDIEKVAHDTPEKILKATIDPLVGAQPYQGRELAFQLGLKGDQIKQFTHIFVGLAKLFQDYDLALLEVNPLVIKKDGNLHCLDAKINIDSNALYRQPKLRAMHDPSQDDAREAHAQKWELNYVALEGNIGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVTEAFKIILSDSNVKAVLVNIFGGIVRCDMIAEGIIGAVKEVGVKVPVVVRLEGNNAELGAKVLAESGLNIIAATSLTDAAQQVVKAAEGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: RS12_ORITB
Sequence: MPTNNQLVRCGRKSKIRASKSPALNGNPFAKGVCVLVKTITPRKPNSALRKMARVRFRNGTCVNAYIPGEGHNLQEHSTVLVRGGRVPDLPGVRYHIVRGVYDTQGVKNRKQGRSRYGTKRPK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RS9_EXISA
Sequence: MADVRYYGTGRRKHSVARVHLVAGDGKVVVNGRDISEYFGHETLIMMAKSPLVLTETEGKYDVIVNVNGGGYTGQAGAIRHGVSRALLQADPEFRPSLKEKGFLTRDARMKERKKYGLKAARRAPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: LEUD_CALS4
Sequence: MQGKAIKYGDNIDTDVIIPARFLNTSDPKELAEHCMEDLDREFKNKVKEGDILVVGENFGCGSSREHAPLAIKASGISCIIAKSFARIFYRNAINIGLPILESREAVDGIEEGDIVSVDVDNGIIRNVTKGTEFKAQPFPEFIKEIIKYGGLINYVREKVR
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 2 subfamily.
Protein: HCS1_ARATH
Sequence: MEAVRSTTTLSNFHLLNILVLRSLKPLHRLSFSFSASAMESDASCSLVLCGKSSVETEVAKGLKNKNSLKLPDNTKVSLILESEAKNLVKDDDNSFNLSLFMNSIITHRFGRFLIWSPRLSSTHDVVSHNFSELPVGSVCVTDIQFKGRGRTKNVWESPKGCLMYSFTLEMEDGRVVPLIQYVVSLAVTEAVKDVCDKKGLPYIDVKIKWPNDLYVNGLKVGGILCTSTYRSKKFNVSVGVGLNVDNGQPTTCLNAVLKGMAPESNLLKREEILGAFFHKFEKFFDLFMDQGFKSLEELYYRTWLHSEQRVIVEDKVEDQVVQNVVTIQGLTSSGYLLAVGDDNQMYELHPDGNSFDFFKGLVRRKI
What is the function of this protein?
Plays a major role in biotin-dependent carboxylase biotinylation (PubMed:18156294).  Catalyzes the addition of biotin to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase (PubMed:9173880, PubMed:9874227, PubMed:18156294).  Can also biotinylate methylcrotonyl-CoA carboxylase (PubMed:9874227, PubMed:18156294).  Is responsible for most, if not all, biotin--protein ligase activity in Arabidopsis (PubMed:18156294).  Is essential for plant viability and required for ovule development (PubMed:18156294).
What are the official names of this protein?
Biotin--protein ligase 1, chloroplastic, Holocarboxylase synthetase 1.
What is the protein family that this protein belongs to?
Belongs to the biotin--protein ligase family.
What are the subcellular locations of this protein?
[Isoform 1]: Plastid, chloroplast. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm, cytosol.
Protein: RLMM_ECOBD
Sequence: MNKVVLLCRPGFEKECAAEITDKAGQREIFGFARVKENAGYVIYECYQPDDGDKLIRELPFSSLIFARQWFVVGELLQHLPPEDRITPIVGMLQGVVEKGGELRVEVADTNESKELLKFCRKFTVPLRAALRDAGVLANYETPKRPVVHVFFIAPGCCYTGYSYSNNNSPFYMGIPRLKFPADAPSRSTLKLEEAFHVFIPADEWDERLANGMWAVDLGACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFKFRPTRSNISWMVCDMVEKPAKVAALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYIQAQLDEHGINAQIQARQLYHDREEVTVHVRRIWAAVGGRRDER
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GP_DOBV
Sequence: MIMWGLLLTMILIDFGASLRNVYDMKIECPHSINFGESSVTGKVELPPLLLTDAEALVPESSCNMDNHQSMSIIQKVTKVSWRKKADKAQAAKDSFETTSSEVNLKGTCALSHRMVEESYRNRRSVICYDLSCNSTHCKPTMHMIVPVHSCNMMKSCLVGLGPYRIQIVYERTYCTTGILTEGKCFVPDQSIVNVIKNGVFDIASVSIVCFFIRVKGTNYKIMASIKTATANNCNDTDNKVQGYYLCIVGGNSSPVYAPSTTDFRSMEALASLLRAPHGEDHDLSGEEVATYSIAGQIEGKIPHTANAANMLFTAFSGIPSYSSLSVFIGSQDGPVIYSPGLFPRLNQSSCDKIALPLIWEGYIDLPGYYETVHPCNVFCVLSGPGASCEAFSEGGIFNITSPTCLVSKQNRFRAAEQQVNFVCQRVDQDIVIYCNGQKKTILTKTLVIGQCIYSVTSLFSIMPGVAHSIAIELCVPGFHGWATAALLTTFCFGWILILSITLAVLVVLKFFAAILHNSSQENRFKIILRKIKEEFEKTKGSMVCEVCKYECETGKELKAHNLSCPQSQCPYCFTHCEPTESAFQAHYKVCQATHRFRDDLKKTITPQSTSPGCYRTLNLFRYKSRCYIFTVWVTLLIIESIMWAASASETVLEPSWNDNAHGVGVVPMHTDLELDFSLPSSSKYTYKRKLTSPLNQEQSVDLHIEIESQGISTSVHALGHWFDGRLNLKTSFHCYGACTKYEYPWHTAKCHFERDFEYENNWGCNPADCPGIGTGCTACGLYIDQLKPVGSAYKLITVRYSRKVCVQFGEENLCKTIDMNDCFVTRHVKVCIIGTVSKFSQGDTLVFLGPMEGGGLIFKDWCTSTCQFGDPGDIMSPKDKGFSCPDFTGHFRKKCNFATTPVCEYDGNMVSGYKKVMATIDSFQSFNTSSIHYTDERIEWKDPDGMLKDHLNILVTKDIDFENLGENPCKVGLQTSSIEGAWGSGVGFTLTCQISLTECSRFLTSIKACDMAICYGAQSVTLIRGQNTVKVSGKGGHSGSSFKCCHGTDCSQQGLQASAPHLDKVNGIVEQESEKVYDDGAPQCGISCWFVKSGEWITGIFNGNWIVIVVLVFFFILSLILLSLLCPIRKHKRS
What is the function of this protein?
Forms homotetramers with glycoprotein N at the surface of the virion.  Attaches the virion to host cell receptors including integrin ITGAV/ITGB3.  This attachment induces virion internalization predominantly through clathrin-dependent endocytosis.  Class II fusion protein that promotes fusion of viral membrane with host endosomal membrane after endocytosis of the virion.
What are the official names of this protein?
Envelopment polyprotein, Glycoprotein precursor, M polyprotein.
What is the protein family that this protein belongs to?
Belongs to the hantavirus envelope glycoprotein family.
What are the subcellular locations of this protein?
[Glycoprotein N]: Virion membrane; Multi-pass membrane protein. Host cell surface. Host Golgi apparatus membrane; Multi-pass membrane protein. Host endoplasmic reticulum membrane; Multi-pass membrane protein. Host mitochondrion. Note=Interaction between glycoprotein N and glycoprotein C is essential for proper targeting of glycoprotein N to the host Golgi complex, where virion budding occurs. SUBCELLULAR LOCATION: [Glycoprotein C]: Virion membrane; Single-pass type I membrane protein. Host cell surface. Host Golgi apparatus membrane; Single-pass type I membrane protein. Host endoplasmic reticulum membrane; Single- pass type I membrane protein. Note=Budding probably takes place at the host Golgi (Probable). Glycoprotein C cytoplasmic tail is important for efficient Golgi localization (By similarity).
Protein: CLPX_PROMH
Sequence: MTDKRKDSSGKLLYCSFCGKSQHEVKKLIAGPSVYICDECVDLCVDIIREEIKELAPHHERSELPTPHEIRKHLDDYVIGQELAKKVLAVAVYNHYKRLRNGDKADGVELGKSNILLIGPTGSGKTLLAETLARYLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVQKAQRGIVYIDEIDKITRKSENPSITRDVSGEGVQQALLKLVEGTVASVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVVAQRLNTHSGIGFGAEVKSQNEKASEGELLAQVEPEDLIKFGLIPEFIGRLPVVATLGELNEDALIQILQEPKNALTKQYQALFKLEGVDLEFRKDALTAIAKKAMSRKTGARGLRSIVEAALLDTMYDLPSFENAEKVVIDENVINGKSEPLIIYSQPENQASGE
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: MTB1_BREEP
Sequence: MKVLSLFSGCGGMDLGLEGGFLAHRSSINSDLYASYISDHDENYVYLKKTGFETVFANDILPFAKLAWCNFFKNRVNQPENIFHLESIVDVVNNIENKQFSFPNDIDVVTGGFPCQDFSFAGKRKGFDSHKDHNGIIYNEPTEATRGQLYLWLKKVVEITKPKVFIAENVKGLVTLGDVKDIIQKDFRNIDDGYVVLDAQVLNAKNYGVAQNRERVIFIGISKRYANKKILDELISLQEKSEVYPYPPYTHGTDPELKPYATLNQILAHLPEPELASTDKSQQSYSKAKLFKKTQGNIEVNMNGQAPTIRAEHHGNIEFRRLSKENGGTNLSELHLPQRRLTVRECALIQSFPPDYEFVFNYGKANSVSASAAYKIIGNAVPPLLGFAIGRHLSQIWDKLFKT
What is the function of this protein?
A methylase, recognizes the double-stranded sequence 5'-CGCG-3', methylates C-1 on both strands, and protects the DNA from cleavage by the BepI endonuclease.
What are the official names of this protein?
Type II methyltransferase M.BepI, M.BepI, Cytosine-specific methyltransferase BepI, Modification methylase BepI.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
Protein: MSHD_AMYMD
Sequence: MSGDGEWRQELDEQQLEDVRRLLLAVREADGRPEVEPAGALPGEFDGGEHLVACVEGEVVGYAHLNTTGNSFGHQVAELFVHPAHRNRGYGAKLLQALDERAAVGFRVWAHGDHPAARKLALKTGLERKRELLILHVDVEGADWPEPILRDGVSLRTFVPGQDEDAVVRVNARAFDWHPEQGALTVEDVRADERRAWFDEDGFFLAEERGEVIGFHWTKVHEPTPGRFGGERVGEVYVVGVDPAAQGGGLGRALTLAGLRYLASRGLRQIILYVEGDNAAALAVYTKLGFTRHETDVQYGR
What is the function of this protein?
Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
What are the official names of this protein?
Mycothiol acetyltransferase, MSH acetyltransferase, Mycothiol synthase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. MshD subfamily.
Protein: RR12_HELSJ
Sequence: MPTLQQLVRKGRIQKHTKTKTPALNNSPQKRGICIRSYTITPKKPNSALRKVARVRLTSKLEITAYIPGIGHNIQEHSVLLIRGGRVKDLPGVRYQIIRGTRDVSGVTARRQSHSKYGTKKVKN
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits (By similarity).
What are the official names of this protein?
Plastid 30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Plastid.