PharMolix/UniProtQA huggingface dataset:
Protein: ALDOC_HUMAN
Sequence: MPHSYPALSAEQKKELSDIALRIVAPGKGILAADESVGSMAKRLSQIGVENTEENRRLYRQVLFSADDRVKKCIGGVIFFHETLYQKDDNGVPFVRTIQDKGIVVGIKVDKGVVPLAGTDGETTTQGLDGLSERCAQYKKDGADFAKWRCVLKISERTPSALAILENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKALSDHHVYLEGTLLKPNMVTPGHACPIKYTPEEIAMATVTALRRTVPPAVPGVTFLSGGQSEEEASFNLNAINRCPLPRPWALTFSYGRALQASALNAWRGQRDNAGAATEEFIKRAEVNGLAAQGKYEGSGEDGGAAAQSLYIANHAY
What are the official names of this protein?
Fructose-bisphosphate aldolase C, Brain-type aldolase.
What is the protein family that this protein belongs to?
Belongs to the class I fructose-bisphosphate aldolase family.
Protein: GSH1_BUCA5
Sequence: MIEDISKKIAWLKKNPKMLKGIFRGIERETLRIQKNGHFSKTIHPYLIGSSLTHKWITTDFSENLLEFITPTSDNIDYLLSFLTDLHSFTASKIKNERMWPFSIPYCFNDQTNIQIAQYGKSNIGKMKTTYRIGLKNRYGDLINTISGIHYNFSLPLFFWTNWENNQNKKNNTDLISSGYLNLIRNYYRFGWIVPYLFGSSPAISSFFLKDTKKKYKFKKNKEDIFYLPWSTSLRLSDIGYSNTNILDLNIMFNDFNEYIESFQNALKTPSKKFINIGLKDEHGNFKQLNTNILQIENELYTQIRPKRKTKDGESLLEALKNRGIEYVEIRSLDVNPFSPIGINKNQILLLDLFLIWCALIDSPKIDKTDFLLTTKNWERIIYEGRKPNQKIYINNNNETKTLIEIGQIIFKDLNEIALILDSNSNNLLYQKACKETQLFLKNPELTYSAQCLNFLMTTGIKKTGLYLANKYHEKFINKNYFNLNQSVLEQEVIRSHQKKIEIEREDILSFEEYIRNK
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
Protein: VF193_IIV6
Sequence: MDTCGIYNSDNEEFSQENDGENDGGDKIIKNLPFASYDERLNSFQNWPIQLLPSKEQLSRAGFIYLNIGDQVQCFYCDLKLKEWKRSDNPFEEHKKHTQDLKINCLFVKSIEFDNFVKNHSESCFQNPITNNINQDLDHNQDLDHNQDLDQNSTTSDCDVLTCKICFTNKITKVLIPCGHSSCYECVFKLQTCPICKNNFIKINNLFI
What is the function of this protein?
Plays a role early in infection by preventing host cell apoptosis.
What are the official names of this protein?
Apoptosis inhibitor 193R.
What is the protein family that this protein belongs to?
Belongs to the IIV-6 193R family.
Protein: TATA_PSYA2
Sequence: MGSFSITHWLILLVVVVVVFGTSKLRNAGKDLGGAVKGFKEAVKDENTEHAKKHVVLDHDAGTNPPNITGTQSDTTSANKVDDTHNV
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RISB_STRZT
Sequence: MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVNEKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: SSPS_STRPY
Sequence: MNTHGKLSKRIKQKFIKQLVAPGAQAAIDQMKFEIASEFGVNLGPDTTACANGFFGAEITKCLVQLREKLGSRY
What are the official names of this protein?
Protein SspS.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta-type SASP family.
Protein: SYI_STRSV
Sequence: MKLKETLNLGKTAFPMRAGLPNKEPIWQKEWDQAKLYQRRQELNEGKPHFILHDGPPYANGNIHVGHAMNKISKDIIVRSKSMAGYYAPYIPGWDTHGLPIEQVLAKQGVKRKELDLVEYLNMCRDYALSQVEKQKEDFKRLGVSGDWENPYVTLTPDYEAAQIRVFGEMAKKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANRVKDGKGVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVVVQPAGESRKFVVASELLNSLSEKFGWADVQVLATYRGQELNHIVTVHPWDTAVDELVILGDHVTTDSGTGIVHTAPGFGEDDYNVGVANDLEVFVTVNERGIMMENAGPDFAGQFYDKVAPTVIEKLGDLLLAQEEISHSYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGDWVISRQRAWGVPLPIFYAEDGTPIMTAETIEHVAQLFEEHGSIVWWKREAKDLLPEGFTHPGSPNGEFTKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSSLITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTSVDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPVEDAVAYEELRSVDKYMTIRFNQLVETIRKAYADFEFLTIYKAIVNFVTVDLSAFYLDFAKDIVYIEAAKSLERRQMQTVFYDVLVKITKLLTPILPHTAEEIWSYLEHEEEEFVQLSELPEAQTFPNQEEILDTWSAFMDFRSQAQKALEEARNEKVIGKSLEAHLTVYPNEVIKTLLEAVNSDVAQLLIVSQLTIAEGPAPEGALVFEDVAFVVEHAQGQVCDRCRRIDTTVQERSYQALVCDHCAEILEENFAQAVSEGFEAN
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRNK_PYRHO
Sequence: MLTEVCKMGTNKAFFTNEVPEDRYIAAEKISSLKKPATVMIIGDVDTGKTTLTIYLANELISRGFRVSIIDSDVGQKSILPPATISLAFVDTHFSSLEDLTPFAHYFVGTITPSQFFGEMVIGVMKLAELAKKFSDVVLIDTTGMIYGPGVELKRMKIEAIKPDLILALERENELTPIIKGFEDITLKLRVSDKVKEFSRSERKELRREKWKRYFENSRIVTFNVNDILVTGTSMFQGKPIEEGEKNLLERLFKWLILHGRKLGERYFVVKVDTSEGPRVVDKNVVRYFDFSKLSNLLLGLLDKEGFCQGVGILKAINFSEGRLEVLTPVKDISIITEIRFGRIRVREDGEELGLLDREVL
What is the function of this protein?
Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of both single-stranded RNA (ssRNA) and single-stranded DNA (ssDNA).  Exhibits a strong preference for ssRNA.
What are the official names of this protein?
Polyribonucleotide 5'-hydroxyl-kinase PH0197, Polynucleotide kinase PH0197.
Protein: COBS_PYRHO
Sequence: MKNILPFLTRIPIKGDFEKARRELWAFPLVSVFTSPLPALILYLKVPLASILALLSLYFTIGLLHLDGLADWADGIMVKGDREKKIKAMKDINVGVAGIFAVVTVLMLQIYSLQLVPFYAIFLAELNSKFAMLLAMATKKPLGKGLGAYFMEALDRNQLLYGTLIYLLLYIPVIIAEPRNLVSFLGLFIGLYAVKISLDNFGGLNGDCIGAVAEITRVGTLVVITLGWRI
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: STMN3_MOUSE
Sequence: MASTVSAYKEKMKELSVLSLICSCFYSQPHPNTIYQYGDMEVKQLDKRASGQSFEVILKSPSDLSPESPVLSSPPKRKDASLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSRLAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREEMSG
What is the function of this protein?
Exhibits microtubule-destabilizing activity, which is antagonized by STAT3.
What are the official names of this protein?
Stathmin-3, Hippocampus abundant transcript 3, SCG10-like protein, SCG10-related protein HiAT3.
What is the protein family that this protein belongs to?
Belongs to the stathmin family.
What are the subcellular locations of this protein?
Golgi apparatus. Cell projection, growth cone. Cell projection, axon. Cytoplasm, cytosol.
Protein: PUR1_STAAM
Sequence: MFNYSGLNEECGVFGIWNHPEAAQLTYMGLHSLQHRGQEGAGIVVSDQNELKGERGLGLLTEAINDDQMERLKGYQHAIGHVRYATSGNKGIENIQPFLYHFYDMSVGICHNGNLINAKSLRQNLEKQGAIFHSSSDTEVIMHLIRRSKAPTFEEALKESLRKVKGGFTFAILTKDALYGAVDPNAIRPLVVGKMKDGTYILASETCAIDVLGAEFVQDIHAGEYVVINDKGITVKSYTHHTTTAISAMEYIYFARPDSTIAGKNVHAVRKASGKKLAQESPVNADMVIGVPNSSLSAASGYAEEIGLPYEMGLVKNQYVARTFIQPTQELREQGVRVKLSAVKDIVDGKNIILVDDSIVRGTTIRRIVKMLKDSGANKVHVRIASPEFMFPSFYGIDVSTTAELISASKSPEEIKDYIGADSLAYLSVDGLIESIGLDYDAPYSGLCVESFTGDYPAGLYDYEANYKAHLSHRQKQYISKNKHFFDSEGNLNV
What is the function of this protein?
Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
What are the official names of this protein?
Amidophosphoribosyltransferase, ATase, Glutamine phosphoribosylpyrophosphate amidotransferase, GPATase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
Protein: FBSP1_DROSI
Sequence: MVDPVAALCNYNVLEVIFSYLELDDLSHCSQVCKSWYHFLNDENSDVWRWHCLNKLPKESLKSDLLSSVSTYKTKLRAYFHAWSPNDCSRNVYIKPNGFTLHRNPVAQSTDAARGKIGFRHGRHTWEVIWEGPLGTVAVIGISTKEAALQCHGYVALLGSDDQSWGWNLVENHLLHNGDMQGSYPLLNNAPKYQVGERIRVILDCEDNTLSFEKNYEFLGVAFRGLPDKKLYPTVSAVYGNTEVSMVYLGTPLDG
What is the function of this protein?
Required in the presynaptic motoneuron to down-regulate the levels of wnd and restrain synaptic terminal growth at the neuromuscular junction (NMJ).
What are the official names of this protein?
F-box/SPRY domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the FBXO45/Fsn family.
What are the subcellular locations of this protein?
Synapse.
Protein: TRMFO_BACAC
Sequence: MTTQVVNVIGAGLAGSEAAYQIAKRGVQVRLYEMRPVRQTPAHHTDKFAELVCSNSLRANTLTNAVGVIKEEMRLMDSVIIRAADECSVPAGGALAVDRHEFAAKVTEYVKNHPNVTVMNEEITEIPEGPTIIATGPLTSPDLSAQLKELTGEDYFYFYDAAAPIVEKDSIDMNKVYLKSRYDKGEAAYLNCPMTEEEFDRFYEALIAAETVPLKEFEKEIFFEGCMPVEVMASRGRQTLVFGPMKPVGLEDPKTGKTPYAVVQLRQDDAAGTLYNIVGFQTHLKWGPQKEVLQLIPGLENAEIVRYGVMHRNTFINSPNLLRPTYQYKQRDDLFFAGQMTGVEGYVESAASGLLAGINAARLVKGEEPVVLPPVTAMGSMANYITATNAKNFQPMNANFGLFAPLEKKIKKKAERNEAYATRALEMIRNFVNI
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPRK_STRPG
Sequence: MTVTVKMLVQKVKLDVVYATDNLLSKEITTSDISRPGLEMTGYFDYYAPERLQLFGMKEWSYLTQMTSHNRYSVLKEMFKKDTPAVVVSRNLAIPKEMVQAAKEEGISLLSSRVSTSRLAGEMSYFLDASLAERTSVHGVLMDIYGMGVLIQGDSGIGKSETGLELVKRGHRLVADDRVDVYAKDEETLWGEPAEILRHLLEIRGVGIIDVMSLYGASAVKDSSQVQLAIYLENFEAGKVFDRLGNGNEEITFSGVRIPRIRIPVKTGRNVSVVIEAAAMNHRAKEMGFDATKTFEDRLTQLITKNEVSQ
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).  The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc. ) in the growth medium.  Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: LEP2_BACAM
Sequence: MTEEQKPTSEKSVKRKSNTYWEWGKAIIIAVALALLIRHFLFEPYLVEGSSMYPTLHDGERLFVNKSVNYIGEIERGDIVIINGDTSKVHYVKRLIGKPGETVEMKNDTLYINGKKIAEPYLASNKKEAKKLGVNLTGDFGPVKVPKGKYFVMGDNRLNSMDSRNGLGLIAENRIVGTSKFVFFPFHDMRQTK
What are the official names of this protein?
Signal peptidase I, SPase I, Leader peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: BRK1_PELRI
Sequence: RPPGFSPFRIAPASSL
What is the function of this protein?
Induces relaxation of arterial smooth muscle, by targeting bradykinin receptors (BDKRB).
What are the official names of this protein?
Bradykinin RL-16-1.
What is the protein family that this protein belongs to?
Belongs to the bradykinin-related peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: HEMH_SYNR3
Sequence: MSRVGIVLLNLGGPERIQDVGPFLYNLFADPEIIRLPIPALQKPLAWLISTLRSNKSQEAYRSIGGGSPLRRITDQQARELQSLLRQRNVDATTYVAMRYWHPFTESAVADMKADGIEQVVVLPLYPHFSISTSGSSFRELQRLRQGDERFAQLPLRAIRSWHDHPGYLKAMAQLMEREIDACVDPSTAHVFFSAHGVPKSYVEEAGDPYQKEIESCAELIMKTLGRDNPWTLAYQSRVGPVEWLQPYTEEALEELGEKGVKELVVVPISFVSEHIETLEEIDIEYREIATEAGVSNFRRVPALDIDPTFIASLADLVETSLAGPEVDLDEAAALPARTKLYPQEKWSWGWNNSSEVWNGRLAMLGFSAFLVELISGHGPLHALGLL
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YTH5_RHOER
Sequence: MRGRLRIERVVTDVGDRLVNVAICTHGHNDHVTVAPELAERLHALVPLHPGATTGRSYSDFPTTIGSIRDRLFALPEETLVHTGHGDGTTIGTEAPHLAEWIARGQ
What are the official names of this protein?
Uncharacterized 11.5 kDa protein in thcD 3'region, ORF5.
Protein: RL2_SALDC
Sequence: MAVVKCKPTSPGRRHVVKVVNPELHKGKPFAPLVEKNSKSGGRNNNGRITTRHIGGGHKQAYRIVDFKRNKDGIPAVVERLEYDPNRSANIALVLYKDGERRYILAPKGLKAGDQIQSGVDAAIKAGNTLPMRNIPVGSTVHNVEMKPGKGGQLARSAGTYVQIVARDGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAARWRGVRPTVRGTAMNPVDHPHGGGEGRNFGKHPVTPWGVQTKGKKTRSNKRTDKFIVRRRSK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: HGT1_KLULA
Sequence: MSLKNWLLLRDIQYEGTFYKKFPHVYNIYVIGFIACISGLMFGFDIASMSSMIGTDVYKDYFSNPDSLTYGGITASMAGGSFLGSLISPNFSDAFGRKVSLHICAALWIIGAILQCAAQDQAMLIVGRVISGMGIGFGSSAAPVYCSEISPPKIRGTISGLFQFSVTVGIMVLFYIGYGCHFIDGAAAFRITWGLQMVPGLILMVGVFFIPESPRWLANHDRWEETSLIVANIVANGDVNNEQVRFQLEEIKEQVIIDSAAKNFGYKDLFRKKTLPKTIVGVSAQMWQQLCGMNVMMYYIVYIFNMAGYTGNTNLVASSIQYVLNVVMTIPALFLIDKFGRRPVLIIGGIFMFTWLFSVAGILATYSVPAPGGVNGDDTVTIQIPSENTSAANGVIASSYLFVCFFAPTWGIGIWIYCSEIFNNMERAKGSALSAATNWAFNFALAMFVPSAFKNISWKTYIIFGVFSVALTIQTFFMFPETKGKTLEEIDQMWVDNIPAWRTANYIPQLPIVKDEEGNKLGLLGNPQHLEDVHSNEKGLLDRSDSASNSN
What is the function of this protein?
High-affinity glucose transporter.
What are the official names of this protein?
High-affinity glucose transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: AT5G_CAEBR
Sequence: MYCQRLALPLTRSLLASRAPLALRMENAVAARMISTTVARKDIDSAAKYIGAGAATVGVAGSGAGIGNVFGALVIGYARNPSLKQQLFSYAILGFALSEAMGLFCLTMGFMILFAL
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  A homomeric c-ring of probably 10 subunits is part of the complex rotary element (By similarity).
What are the official names of this protein?
ATP synthase lipid-binding protein, mitochondrial, ATPase protein 9, ATPase subunit c.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: TYPH_PROMH
Sequence: MFLAQEIIRKKRDGHPLTEEEIRFFINGVRDNTVSEGQIAALAMTIYFHDMTMPERVALTLAMRDSGTVLNWKSLNLNGPIVDKHSTGGVGDVTSLMLGPMVAACGGYVPMISGRGLGHTGGTLDKLEAIPGFDIFPDDEKFRDIIRHVGVAIIGQTNSLAPADKRFYATRDITATVDSIPLITASILGKKLAEGLDALVMDVKVGSGAFMPTYQKSEELAESIVQVANGAGCQTTALLTDMNEVLASSAGNAVEVREAVQFLTGEYRNPRLFEVTMALCVEMLVSGRLADSRQQARQKLQDVLDNGKAAEVFARMVAAQNGPTDFVENYNKYLPTAVLSKPVFAEKAGFVTEMDTRALGMSVVTLGGGRRKATDAIDYSVGLSEIAALGTEINTDTPLAMIHANSEKSWQEAAAEVRKAMVIGETKRETSPMVYRQVSE
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: OSP_DROME
Sequence: MSTTTITTTVPAAPSKSAPPTPTTTGAAGATTNARTADCRKFTPNIFNKSKCSHCFRQREEHSAAALECNRRTSSNLAEPASRKVSKCGYLFVAPDWDFSNPLYRTKRWQRRWFVLYDDGELTYSVDDYPETIPQACVDMTKVLEVTSAVEVTGHPNSIAITAPERVTFVKGTSSEESQWWLNILAAFPKSKGRHKRSATLPGGQVVGSLRPTSNGDLTLSTKLGNRHSSYHKDTLTSSQSAGNLLSSLDLGPSSTKTAGSPLTTTQSALADDEEDDGVETGEDVDEDEEDETSVPRKSKTVSMGGQDENNRNAGNEITNRVSQPTTCLLIEDIRRDEKTIKDIANTITNLSQQQNKRWSTAVNNALNNQHHFGHHSQYQVTSRDETDFQMSSNSSSTKSQNPASERPKSLPLASNSTPAIVSAIVKKIPTVMEQGDKTKPTARLQLHLKSPKHYQHERGDPDGGCNLDELCVNYMAKTDELRSVGKANSKSSSGQGKPPVKEESLNAKKGWLMKQDNRTCEWSKHWFTLSGAALFYYRDPLCEERGVLDGVLDVNSLTSVIPEPAASKQHAFQLTTWDKQRLVLASLSPSSRNSWLAVLRSAAGLPQLDTPPKQTDIEQDFIKAQLQQPSSSPVTPGTPAGPHFSSDEEYRTASEGGRRDSLDWGSPLSPSPPVLRSCLRNRSLASLHKRSRSSPPSSRRSTVDSVASDELPLLVVPEEMQPTESRELKQQCETLRAEASLREARMSELLATLQRTEQQLTARLQEQQQQLNSELTQAKQSASDLMHNLGMQLTESQCQIKQLEDRLAQGIEENEGLYKRLRELQAQDHSGGAALSNLQRHKIKRMDSLSDLTTISDIDPYCLQRDSLAEEYNELRSRFEKAVNEIRAMKRELKQSQNQYDALELAQAALQQKLERRQHEDGAQLQLMAARIQDLTLKYSSSERQVRALKQKLAKSERRRSLSLKGKEQLELKLSELQRETVERKEGTPPESSSSESSSQSPLNAHLLQRLHSLEHVLLGSKERLEQSLTQLQQIRAGQRTRRSVSPMNDRKDGLRQLERALAETCVMVSEQMELTCLQDSCHKCCDLRQRVEKLSALQQQTETDLQRSEQLLEQRETDLAQALEKCASQEQEQELLLQQRQELSEELGRQQERCRRLEKRLELLEREHGKQLECLREVYHTEHANAADEQSFRKRYQTEIEQLRTLCEKGLSAMETSHKRLTMDLEQKHKMEIERLLAEKETALAEETQATLAALDAMRKAHQSEVQREVARFKQEFLRQVQRGEQMRGDGAKLKEEDLGELRMEILAFSEKYSIKCVENAALEEKLHMANSKLRHFQQMQQLELRNKQFRAHLASDDPSNDVHFVQGLTSDAREDADCEDSEPAPQILGATATRTTATTTTTATATTTSAAPSETESNPDSDRETADSSRAPPEKMEQSLFVIPSHMLNSSLVPAANASDQSQRSQLYRDLDGPEDGYEPCYRPFDIFAIYQNRLSYQGLKGSSTFGKSLRKSAAQTSPASSEITTTTTAPTTDPKKPSHKQMFKTAAVINIQQQVAQEEKAQ
What are the official names of this protein?
Protein outspread.
Protein: ACKA_MYCPU
Sequence: MKILVINAGSSSIKFALFEKENLNQIASGIAERIGIENGIISISFDKKYQFEIDMKDHLEAAKKLLELFEQISLIKNADEIELIGFRVVHGGIELNKASKLDQETISIIEKSAKYAPLHNPGALQAIKAFQLALPKAKLSVNLDTAFHSSIDKINYSYPINYELAQKLGIRKFGFHGISHRFITNKLEKILNKKSVNFVNLHIGNGASLCAVKVSKSIDTSMGFTPLAGIMMGTRSGDIDPSIHEFVCKEENMSIEEFTSILNKQSGISGVSQISSDLRDVEEQYAKGNAQAIFALDLYSQKIADYAAIYLNKIAPQIDAIVFTAGVGENSAFVRKNVISRIKIKNIELDEALNSQKVGEYQLISTKNSEIPVYVIRTNEELMIASDAKKLNS
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2216_MYCTU
Sequence: MANAVVAIAGSSGLIGSALTAALRAADHTVLRIVRRAPANSEELHWNPESGEFDPHALTDVDAVVNLCGVNIAQRRWSGAFKQSLRDSRITPTEVLSAAVADAGVATLINASAVGYYGNTKDRVVDENDSAGTGFLAQLCVDWETATRPAQQSGARVVLARTGVVLSPAGGMLRRMRPLFSVGLGARLGSGRQYMSWISLEDEVRALQFAIAQPNLSGPVNLTGPAPVTNAEFTTAFGRAVNRPTPLMLPSVAVRAAFGEFADEGLLIGQRAIPSALERAGFQFHHNTIGEALGYATTRPG
What are the official names of this protein?
Epimerase family protein Rv2216.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.
Protein: PFDA_THEAC
Sequence: MARDVEAQLNYIESLISSVDSQIDTLNKAMIEVQSTIDLLSNGDLASSPEKLISIGSGLFAKGNITIDEDLIVPIGSGIYVAETKERSVERLKKNLEDIKASIQKLLDQRKTLVDQYNTVYATEATRNVK
What is the function of this protein?
Molecular chaperone capable of stabilizing a range of proteins.  Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding (By similarity).
What are the official names of this protein?
Prefoldin subunit alpha, GimC subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit alpha family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSUG_NOCSJ
Sequence: MTAPHPLLTLTDEVADALRDGAPVVALESTIISHGMPYPQNVAMATEVEGIIRAAGAVPATIAVLEGRPRIGLTADDLELLASDEDVAKVSVRDLPFVVARRSHGATTVAATMRLAALAGIRVFVTGGLGGVHRGAQQSFDESADLTELGSTDVAVISAGVKSILDIGLTLERLETLGVPVLAYGSDEFPSFYSRSSGHAAPMRVDSAAEVAAVMAAKWDLGIAGGVVVANPIPEADEIPADEIGGIIEQALADMAARGIHGNEATPYLLGRIVEITGGASLTANIALVRANARLGASIAREYAGLR
What is the function of this protein?
Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil.  Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
What are the official names of this protein?
Pseudouridine-5'-phosphate glycosidase, PsiMP glycosidase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine-5'-phosphate glycosidase family.
Protein: HIS8_ESCF3
Sequence: MSTVTITDLARENVRNLTPYQSARRLGGNGDVWLNANEYPTAVEFQLTQQTLNRYPECQPKAVIDNYAQYAGVKPEQVLVSRGADEGIELLIRAFCEPGKDAILYCPPTYGMYSVSAETIGVECRTVPTLENWQLDLQGISDKLDGVKVVYVCSPNNPTGQLINPQDFRTLLELTRGKAIVVADEAYIEFCPQASLAGWLAEYPHLAILRTLSKAFALAGLRCGFTLANEDVINLLMKVIAPYPLSTPVADIAAQALSPQGILAMRERVVQIIAEREYLIGALKEIPCVEQVFDSETNYILARFKASSAVFKSLWDQGIILRDQNKQPSLSGCLRITVGTREESQRVIDALRAEQV
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: ULAB_SHISS
Sequence: MTVRILAVCGNGQGSSMIMRMKVDQFLTQSNIDHTVNSCAVGEYKSELSGADIIIASTHIAGEITVTGNKYVVGVRNMLSPADFGPKLLEVIKAHFPQDVK
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II UlaABC PTS system is involved in ascorbate transport.
What are the official names of this protein?
Ascorbate-specific PTS system EIIB component, Ascorbate-specific phosphotransferase enzyme IIB component.
What are the subcellular locations of this protein?
Cytoplasm.