PharMolix/UniProtQA huggingface dataset:
Protein: DNAK_RHOP2
Sequence: MGKVIGIDLGTTNSCVAVMDGKNSKVIENAEGMRTTPSIVAFSDDGERLVGQPAKRQAVTNPERTFFAVKRLVGRRYDDPMVEKDKKLVPYKIVKASNGDAWVEADGQTYSPSQVSAFILQKMKETAEAHLGQKVDQAVITVPAYFNDAQRQATKDAGKIAGLEVLRIINEPTAAALAYGLDKTKAGTIAVYDLGGGTFDVSILEIGDGVFEVKSTNGDTFLGGEDFDMRLVSYLADEFQKEQGINLRNDKLALQRLKEAAEKAKIELSSTTQTEINLPFITADQSGPKHLTMKLTRAKFEALVDDLVQKTIEPCRKALKDAGLTAGEIGEVVLVGGMTRMPKVQEVVKQLFGKEPHKGVNPDEVVAIGAAIQAGVLQGDVKDVLLLDVTPLSLGIETLGGVFTRIIERNTTIPTKKSQVFSTAEDNQNAVTIRVFQGEREMAADNKILGQFDLMGIPPAPRGMPQIEVTFDIDANGIVNVSAKDKATGKEQQIRIQASGGLSDSDIDKMVKDAEANAAEDKKRREAVDAKNHADALVHSTEKALAEHGSKVAEPERRAIEDALSDLRESLKSDDAEVIKAKTNTLAQASMKLGEAMYTQQAESDAAKHAAKDDIVDADFTEVDDDKNNKKSA
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RHSE_ECOLI
Sequence: MSTRLTTLSHTSEGHRVSVHYGYDDKGRLTGERQTVENPETGELLWHHETGHAYNEQGLANRVTPDSLPPVEWLTYGSGYLAGMKLGGTPLLEFTRDRLHRETVRSFGSMAGSNAAYKLTSTYTPAGQLQSQHLNSLVYDRDYGWNDNGDLVRISGPRQTREYGYSATGRLESVRTLAPDLDIRIPYATDPAGNRLPDPELHPDSTLTVWPDNRIAEDAHYVYRHDEYGRLTEKTDRIPAGVIRTDDERTHHYHYDSQHRLVFYTRIQHGEPLVESRYLYDPLGRRMAKRVWRRERDLTGWMSLSRKPEVTWYGWDGDRLTTVQTDTTRIQTVYEPGSFTPLIRVETENGEREKAQRRSLAETLQQEGSENGHGVVFPAELVRLLDRLEEEIRADRVSSESRAWLAQCGLTVEQLARQVEPEYTPARKVHFYHCDHRGLPLALISEDGNTAWRGEYDEWGNQLNEENPHHLHQPYRLPGQQHDEESGLYYNRHRHYDPLQGRYITPDPIGLRGGWNMYQYPLNPIQVIDPMGLDAIENMTSGGLIYAVSGVPGLIAANSITNSAYQFGYDMDAIVGGAHNGAADAMRHCYLMCRMTKTFGSTIADVIGKNHEAAGDRQGQPAKERIMDLKNNTVGIACGDFSAKCSDACIEKYNTGQLFGLDGIKADNPIKAKQGSSDASNY
What is the function of this protein?
Rhs elements have a nonessential function.  They may play an important role in the natural ecology of the cell.
What are the official names of this protein?
Putative protein RhsE.
What is the protein family that this protein belongs to?
Belongs to the RHS family.
Protein: HIS1_ACTP7
Sequence: MTTTNRLRIALQKKGRLSKDCNELLKQCGVKINWNEQRLIAYAENMPIEILRVRDDDIPGLVFEGVVDLGIIGENVLEEEELGRLARGEKIEYKKLRTLDFGGCRLSLAIDRDRTYNGVQDFVNSRIATSYPNLLKRYMNEKGVAFKSTLLNGSVEVAPSAGLADAICDLVSSGATLEANGLKEVEVIYQSKACLIQRAEPLSAEKQALVDRLLTRIQGVQQAAESKYIMLHAPKDKLKEITALLPGVENPTILPLANDSARVAMHVVSQENLFWETMEQLKEMGASSVLVLPIEKMLA
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KISHA_XENLA
Sequence: MSAIFNFQSLLIVILLLICTCAYLRSLVPNLLDKNKTGVLGIFWKCARIGERKSPYVAVCCVVMAFSILFMQ
What is the function of this protein?
Involved in the early part of the secretory pathway.
What are the official names of this protein?
Protein kish-A, Transmembrane protein 167A.
What is the protein family that this protein belongs to?
Belongs to the KISH family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type I membrane protein.
Protein: RL24_PHYAS
Sequence: MRIKVGETVAILAGKDRYFIDENGQRKVKTGKVLKIFNEKQRIIVEGVNMKTKHHPPSKDQEKGSITKQEGSIHISNVALIDPKTQTPTKIGIRFKKGKKIRYAKKSNNQLDDIV
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: RL4_YERPE
Sequence: MELVMKDAPGALTVSETTFGRDFNEALVHQVVVAYAAGARQGTRAQKTRAEVTGSGKKPWRQKGTGRARAGSVKSPIWRSGGVTFAAKPQDHSQKVNKKMYRGALKSILSELVRQDRLIIVEKFSVEAPKTKLLAQKLKDMALEDVLIVTGELDENLFLAARNLYKVDVRDVAGIDPVSLIAFDKVVMTADAVKQVEEMLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: RL29_SOLM1
Sequence: MKTAELRDLDIEALGKKLGESREELFKLRFQHATAQLEKTHRLREVRKDIARIMTVQTEKKRQG
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: PDF2_ARATH
Sequence: MYHPNMFESHHMFDMTPKSTSDNDLGITGSREDDFETKSGTEVTTENPSGEELQDPSQRPNKKKRYHRHTQRQIQELESFFKECPHPDDKQRKELSRDLNLEPLQVKFWFQNKRTQMKAQSERHENQILKSDNDKLRAENNRYKEALSNATCPNCGGPAAIGEMSFDEQHLRIENARLREEIDRISAIAAKYVGKPLGSSFAPLAIHAPSRSLDLEVGNFGNQTGFVGEMYGTGDILRSVSIPSETDKPIIVELAVAAMEELVRMAQTGDPLWLSTDNSVEILNEEEYFRTFPRGIGPKPLGLRSEASRQSAVVIMNHINLVEILMDVNQWSCVFSGIVSRALTLEVLSTGVAGNYNGALQVMTAEFQVPSPLVPTRENYFVRYCKQHSDGSWAVVDVSLDSLRPSTPILRTRRRPSGCLIQELPNGYSKVTWIEHMEVDDRSVHNMYKPLVQSGLAFGAKRWVATLERQCERLASSMASNIPGDLSVITSPEGRKSMLKLAERMVMSFCSGVGASTAHAWTTMSTTGSDDVRVMTRKSMDDPGRPPGIVLSAATSFWIPVAPKRVFDFLRDENSRKEWDILSNGGMVQEMAHIANGHEPGNCVSLLRVNSGNSSQSNMLILQESCTDASGSYVIYAPVDIVAMNVVLSGGDPDYVALLPSGFAILPDGSVGGGDGNQHQEMVSTTSSGSCGGSLLTVAFQILVDSVPTAKLSLGSVATVNSLIKCTVERIKAAVSCDVGGGA
What is the function of this protein?
Probable transcription factor that binds to the L1 box DNA sequence 5'-TAAATG[CT]A-3'.  Plays a role in maintaining the identity of L1 cells, possibly by interacting with their L1 box or other target-gene promoters; binds to the LIP1 gene promoter and stimulates its expression upon imbibition (PubMed:24989044).  Acts as a positive regulator of gibberellins (GAs)-regulated epidermal gene expression (e. g.  LIP1, LIP2, LTP1, FDH and PDF1) (PubMed:24989044).  Functionally redundant to ATML1 (PubMed:24989044).  Involved, together with HDG proteins (e. g.  HDG1, HDG2, HDG5 and HDG12), in the regulation of flower organs development by promoting the expression of APETALA 3 (AP3) in the epidermis and internal cell layers of developing flowers (PubMed:23590515).  Seems to promote cell differentiation (PubMed:25564655).
What are the official names of this protein?
Homeobox-leucine zipper protein PROTODERMAL FACTOR 2, HD-ZIP protein PDF2, Homeodomain transcription factor PDF2.
What is the protein family that this protein belongs to?
Belongs to the HD-ZIP homeobox family. Class IV subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PP188_ARATH
Sequence: MIWSSDSCFKSRKHQCLIFLKLCSSIKHLLQIHGQIHLSSLQNDSFIISELVRVSSLSLAKDLAFARTLLLHSSDSTPSTWNMLSRGYSSSDSPVESIWVYSEMKRRGIKPNKLTFPFLLKACASFLGLTAGRQIQVEVLKHGFDFDVYVGNNLIHLYGTCKKTSDARKVFDEMTERNVVSWNSIMTALVENGKLNLVFECFCEMIGKRFCPDETTMVVLLSACGGNLSLGKLVHSQVMVRELELNCRLGTALVDMYAKSGGLEYARLVFERMVDKNVWTWSAMIVGLAQYGFAEEALQLFSKMMKESSVRPNYVTFLGVLCACSHTGLVDDGYKYFHEMEKIHKIKPMMIHYGAMVDILGRAGRLNEAYDFIKKMPFEPDAVVWRTLLSACSIHHDEDDEGIGEKVKKRLIELEPKRSGNLVIVANRFAEARMWAEAAEVRRVMKETKMKKIAGESCLELGGSFHRFFSGYDPRSEYVSIYELLDLFKFQLTCDYRLVSE
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At2g36730.
What is the protein family that this protein belongs to?
Belongs to the PPR family. PCMP-E subfamily.
Protein: SYN_CLOPE
Sequence: MKDVVLVKSLYRNTSEYSDKKVKISGWIRTLRASNAFGFIEVNDGSFFKNVQVVFDSAKISNYKEISKLPISSSISVIGTLVETPDSKQPFEIQAEEIIVEGMSDSDYPLQKKRHTFEYLRTIAHLRPRSNAFSATFRVRSVAAYAIHKFFQDQGFVYTHTPILTGSDCEGAGEMFRVTTLDMMAPPIAEEGGIDFSQDFFGKETNLTVSGQLNAECFALAFRNIYTFGPTFRAENSNTVKHAAEFWMIEPEMAFADLIDDMEVAENMLKYVIKYVMDECPEEIAFFNQFVDKGLLERLNHVVNSEFGKVTYTEAVKLLQESGKEFEYPVEWGIDLQTEHERYLTEQIFKKPVFVTDYPKDIKAFYMRLNEDGKTVAAMDCLVPGIGEIIGGSQREERLDVLKARMAELNLNEEDYWWYLELRKYGETVHSGFGLGFERLIMYITGMANIRDVIPFPRTTGTAEF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS4_ACIB5
Sequence: MLIIPAIDLKDGKCVRLKQGRMEDDTVFSDDPVATAQHWVNEGARRLHLVDLNGAFAGTPIHKPVVEAIAKAQPELPIQIGGGIRSLETIEHYLEAGVTFVIIGTKAVQEPEFVEEACKRFAGHIIVGIDAMNGMVATDGWANVTDVKATDLAKRFADAGVSSIVYTDIARDGMMQGVNVEQTVNLAQYSGLPVIASGGVTNLDDVRNLKGQPGILGAITGRAIYEGTLNLREAQLLLDENRL
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IAMY_COILA
Sequence: CCSKFGYCGLTDAYNFYTGQLTSFAHVTHETGNNAYCDPSKTQKPCAAGKKYYGRGPIQISXNYNYGPAGRAIGMDGLGNPDRVAQDALDDYKTALXFLVNGEEAVPGLSAANAVSYYRQYCQQLGVDPGPNL
What is the function of this protein?
This protein functions both as an alpha-amylase inhibitor and as a chitinase.
What are the official names of this protein?
Alpha-amylase inhibitor/endochitinase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 19 family. Chitinase class I subfamily.
Protein: MURD_LACE2
Sequence: MDLKNKTVMVVGTGISGIGAVDLLNKVGADCILYDGNEKLDRQKVQEKLGDNKAEIIIGAFDEALLSKIDLLVISPGVPIDSPIVLTFKNAGIPVWGEIELAYNYDKGKIIAITGTNGKTTTTALVGQIIAAYNEKTFVVGNIGNSYTGEVLKTSEDSYTVAEISSFQLETVHEFHPIVSAILNITPDHLNRHHTMECYAWTKERISENQTKADTCVLNLEDKYLTDFAPECKANVVWFSSERKPSVGAYVDGEMIKYTDGTNDYDMLNVHDMNLLGKHNYENVCAAIAMTKAAGIPDDIIIEQVKKFKAVEHRIEYVATKNGVDYYNDSKGTNPEAAVKAIEAMVKPTILIGGGYDKGSEFDLYVKAFKDKVKLLVLIGQTSAKIADTCKKYGFENIEYADSMEQVVDICAKNAVSGDAVLLSPACASWGMFDNYEQRGRIFKDLVNNL
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEFI_MYTGA
Sequence: GFGCPNNYQCHRHCKSIPGRCGGYCGGWHRLRCTCYRCGGRREDVEDIFDIFDNEAADRF
What is the function of this protein?
Active against both Gram-positive and Gram-negative bacteria but is not cytotoxic towards human erythrocytes or protozoa (PubMed:8925841).
What are the official names of this protein?
Defensin MGD-1, Defensin-like peptide, DLP, Mytilus galloprovincialis defensin 1, MGD1.
What is the protein family that this protein belongs to?
Belongs to the invertebrate defensin family. Type 2 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SYH_MARSD
Sequence: MAKIQKIKGVADLFPEDSARYAFMEKTARDVFSSYGYGELRVPILEKTELFCRSIGEETDVVQKEMYTFPDRKGRSLTMRPEATAGIVRAYVENKIYQPGKVSKFFTFGPMFRYERPQAGRMRQFHQIDAEIFGAAEPQADAEVLLMLSSFLSNIGLEKLSFELNSLGCPECRPKYNQALKDFLASLDREQLCDDCQRRMDTNPLRVLDCKSKNCKALTENAPTLPDHLCGECREHFDTVIALIDEAGLQYTLNPRLVRGLDYYQRTAFEVTSGDIGAQTAVAGGGRYDGLVESLGGPKKVPAIGFACGMERLAMLLEGEFEPAADFYVALVDERAAKDSLIFGEKLRRSGLKGEVGFTAKSMKAQLRHANKINAQKCFIFGAEEFENGTVTIKDMAEGGEQETVSRDEYFK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SL9A3_DIDVI
Sequence: MPLGVRGTRREFRFPVWGLLLLALWMLPRALGVEEIPGPDSHEKQGFQIVTFKWHHVQDPYIIALWILVASLAKIVFHLSHKVTSVVPESALLIVLGLILGGIVWAADHIASFTLTPTVFFFYLLPPIVLDAGYFMPNRLFFGNLGTILLYAVIGTVWNAATTGLSLYGVYLSGIMGDLSIGLLDFLLFGSLIAAVDPVAVLAVFEEVHVNDVLFIIVFGESLLNDAVTVVLYNVFDSFVSLGADKVTGVDCVKGIVSFFVVSLGGTLIGIIFAFLLSLVTRFTKHVRIIEPGFVFIISYLSYLTSEMLSLSAILAITFCGICCQKYVKANISEQSATTVRYTMKMLASGAETIIFMFLGISAVDPAIWTWNTAFILLTLVFISVYRAIGVVLQTWLLNKYRMVQLEIIDQVVMSYGGLRGAVAYALVVLLDEKKVKEKNLFVSTTIIVVFFTVIFQGLTIKPLVQWLKVKKSEHREPKLNEKLHGRAFDHILSAIEDISGQIGHNYLRDKWSNFDRKVLSKLLMRRSAQKSRDRILNVFHELNLKDAISYVAEGERRGSLAFIRSPSTDNIVNVDFSTPRPSTVEASVSYLLRENVSTVCLDMQALEQRRKSIRDTEDTVTHHTLQQYLYKPRQEYKHLYSRHELTSNEDEKQDKEIFHRTMRKRLESFKSTKLGINQTKKTAKLYKRERGQKRRNSSIPNGKIPMESPTRDFTFKEKELEFSDPEETNEYEAEEMSGGIEFLANVTQDTATDSTTGIDNPVFSPEEDQSIFTKVPPWLSPEETVVPSQRARVQIPYSPSNFRRLTPIRLSTKSVDSFLLADSPEERPRSFLPESTHM
What is the function of this protein?
Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions.  Major proton extruding system driven by the inward sodium ion chemical gradient.  Plays an important role in signal transduction.
What are the official names of this protein?
Sodium/hydrogen exchanger 3, Na(+)/H(+) exchanger 3, NHE-3, Solute carrier family 9 member 3.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Note=In intestinal epithelial cells, localizes to the ileal brush border (By similarity). Phosphorylation at Ser-669 by SGK1 is associated with increased abundance at the cell membrane. Angiotensin-2 enhances apical expression (PubMed:20584908).
Protein: YAFQ_ECOBD
Sequence: MIQRDIEYSGQFSKDVKLAQKRHKDMNKLKYLMTLLINNTLPLPAVYKDHPLQSSWKGYRDAHVEPDWILIYKLTDKLLRFERTGTHAALFG
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system (PubMed:24923448).  A sequence-specific mRNA endoribonuclease that inhibits translation elongation and induces bacterial stasis (Probable).  Cleavage occurs between the second and third residue of the Lys codon followed by a G or A (5'AAA(G/A)3'), is reading-frame dependent and occurs within the 5' end of most mRNAs (By similarity).  Ribosome-binding confers the sequence specificity and reading frame-dependence (By similarity).  The YafQ-DinJ heterotetramer binds the consensus sequence 5'-TTTGAGCTACA-3' in the dinJ promoter; DinJ also binds DNA but not as well as the YafQ-DinJ complex (PubMed:24923448).
What are the official names of this protein?
mRNA interferase toxin YafQ, Endoribonuclease YafQ, Toxin YafQ.
What is the protein family that this protein belongs to?
Belongs to the RelE toxin family. YafQ subfamily.
Protein: TRPF_BRUAB
Sequence: MALDIKICGLKTPEAVAAALDGGATHIGFIFFPKSPRHITPDAAARLRAAATGRAVAVAVTVDADDEALDEIVKTVRPDMLQLHGGETPERVRFLKERYNLPVMKAFSIREAGDLEAIAPYRGIADRFLFDAKPPKGSELPGGNGISFDWNLLAALDADIDYMLSGGLNADNIAEALLKTGAPGIDISSGVECAPGEKDVRLIENFFQAVADANAQPFARRA
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: RLR05_PLAHL
Sequence: MRGAFYVATAFLIASSTRTAAESVQIKSEITQDLDKLPVGDSDTKSLPRRSLKGSGDRLEIPVAEEERVIPTGVLEGAGKDVSEAILRLEKSGDDLNKMVKVGEGVGSSATSKGKRIQIFQKSHKDAVAEHQQVFDTYKHAIKKNEALELERDTALIKSHNWKLLSDYFSAQAAKDTKNYHNYHTIFSQLDSVVTPATASYKGIKNTREKYLALLEESFSRANAAKHAGNMDEYNEIQVTVAEL
What is the function of this protein?
Secreted effector that suppresses pattern-triggered immunity (PTI) in plant host.
What are the official names of this protein?
Secreted RxLR effector protein RXLR-C05.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Host nucleus.
Protein: RS7_ARTS2
Sequence: MPRKGPAPKRPLVLDPVYGSPLVTQLINKVLVDGKKSTAERIVYGALEGARAKSGGDPVAALKKAMENVKPSLEVRSRRVGGATYQVPVEVKPGRSTALALRWLVGYSKARREKTMTERLQNEILDASNGLGAAVKRREDTHKMAESNKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: DUS15_HUMAN
Sequence: MTEGVLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTPEVPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKATRPIANPNPGFRQQLEEFGWASSQKGARHRTSKTSGAQCPPMTSATCLLAARVALLSAALVREATGRTAQRCRLSPRAAAERLLGPPPHVAAGWSPDPKYQICLCFGEEDPGPTQHPKEQLIMADVQVQLRPGSSSCTLSASTERPDGSSTPGNPDGITHLQCSCLHPKRAASSSCTR
What is the function of this protein?
May play a role in the regulation of oligodendrocyte differentiation.  May play a role in the regulation of myelin formation (By similarity).  Involved in the regulation of Erk1/2 phosphorylation in Schwann cells; the signaling may be linked to the regulation of myelination (By similarity).
What are the official names of this protein?
Dual specificity protein phosphatase 15, VH1-related member Y, Vaccinia virus VH1-related dual-specific protein phosphatase Y.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
What are the subcellular locations of this protein?
Cytoplasm. SUBCELLULAR LOCATION: [Isoform 3]: Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: RECR_CHLTR
Sequence: MLKYPDYISKLISFLKKLPGIGFKSAEKIAFELLEWDPSQIEAMAQALQEFSTSHATCSNCFCLKISQTSPCNFCSESRDSSSLCIVATPKDVFALEKSKIFKGHYFVLGNLLSPITGKHLSLEKLAILKQRIEACSPKEMIIALDATLEGDATALFLKQEFSYLPIKISRLALGMPVGLSFDFVDANTLARAFSGRNCF
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: OTU5A_DANRE
Sequence: MTILPKKKPNSSVGVSDHPDDPDRRTGSDPHQHQHQHSHGVRPGARPRASPPPWSYQAAPPASREDRRTESSSRPQQASPPPVGAGSSGGPGDATGMACVSGNRAELSGGVGCGGGMGGCCSGPGLSKRRRQATCSGGVAGGGTGPGAAGGGGGGGGGGGVGGPSPEQEEGAGYNSEDEYENASRLQSEDPATVEQQEHWFEKALQEKKGFVIKKMKEDGACLFRAVADQVYGDQDMHEVVRKHCMDYLMKNADYFSNYVTEDFTTYINRKRKNNCHGNHIEMQAMAEMYNRPVEVYQSGTEPINTFHGIHQNNDEPIRVSYHRNIHYNSVVNPNKATIGVGLGLPAFKPGFADQSLMKNAIKTSEESWIEQQMLEDKKRATDWEATNEAIEEQVARESYLQWLRDQEKQARQPRKASATCSSATAAASSGLEEWNARSPRQRSSAPSPEIPDPAHSDTAAKPPSPAGALALSKPPSPCAPGPSNQACVGPDRPTSSSLVSLYPALGYRAIMQEMSPTAFGLTDWEDDEILASVLAVSQQEYLDSMKKNAMHREPSPDSS
What is the function of this protein?
Deubiquitinating enzyme that may function as negative regulator of the innate immune system.  Has peptidase activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.  Can also cleave 'Lys-11'-linked ubiquitin chains (in vitro) (By similarity).
What are the official names of this protein?
OTU domain-containing protein 5-A, Deubiquitinating enzyme A, DUBA.
What is the protein family that this protein belongs to?
Belongs to the peptidase C85 family.
Protein: GCSPA_STAA8
Sequence: MSHRYIPLTEKDKQEMLQTIGAKSIGELFGDVPSDILLNRDLNIAEGEAETTLLRRLNRIASKNITKETHTSFLGAGVYDHYAPSVVDAMISRSEFYTAYTPYQPEISQGELQAIFEFQTLICELTDMDVANSSMYDGMTSFAEACILAFSQTKKNKIVVSKGLHYQALQVLHTYAKTRKEFEVVEIDLDGTVTDLKKLEAAVDDETAAVAVQYPNFYGSIEDLEKIHSFIEDKKALFIVYANPLALGLLTPPGSFGADIVVGDTQPFGIPAQFGGPHCGYFATTKKLMRKVPGRLVGQTQDDEGNRGFVLTLQAREQHIRRDKATSNICSNQALNALASSIAMSALGKQGIYDIAVQNIEHANYAKQQFIKKGFEVLDGTSFNEFVVKFDKPIQQVNEELVKYNIIGGFDLGVVSDDFKNHMLIAVTELRTKDEIDTFVEKAGELND
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: 4CLL5_ARATH
Sequence: MASVNSRSGFCNSNSTFYSKRTPIPLPPNPSLDVTTFISSQAHRGRIAFIDASTGQNLTFTELWRAVESVADCLSEIGIRKGHVVLLLSPNSILFPVVCLSVMSLGAIITTTNPLNTSNEIAKQIKDSNPVLAFTTSQLLPKISAAAKKLPIVLMDEERVDSVGDVRRLVEMMKKEPSGNRVKERVDQDDTATLLYSSGTTGMSKGVISSHRNLIAMVQTIVNRFGSDDGEQRFICTVPMFHIYGLAAFATGLLAYGSTIIVLSKFEMHEMMSAIGKYQATSLPLVPPILVAMVNGADQIKAKYDLSSMHTVLCGGAPLSKEVTEGFAEKYPTVKILQGYGLTESTGIGASTDTVEESRRYGTAGKLSASMEGRIVDPVTGQILGPKQTGELWLKGPSIMKGYFSNEEATSSTLDSEGWLRTGDLCYIDEDGFIFVVDRLKELIKYKGYQVAPAELEALLLTHPEITDAAVIPFPDKEVGQFPMAYVVRKTGSSLSEKTIMEFVAKQVAPYKRIRKVAFVSSIPKNPSGKILRKDLIKIATSNSKL
What is the function of this protein?
Contributes to jasmonic acid biosynthesis by initiating the beta-oxidative chain shortening of its precursors (PubMed:16963437, PubMed:18267944).  Converts 12-oxo-phytodienoic acid (OPDA) and 3-oxo-2-(2'-pentenyl)-cyclopentane-1-octanoic acid (OPC-8:0) into OPDA-CoA and OPC-8:0-CoA, respectively (PubMed:16963437, PubMed:18267944).  Follows a two-step reaction mechanism, wherein the carboxylate substrate first undergoes adenylation by ATP, followed by a thioesterification in the presence of CoA to yield the final CoA thioester (By similarity).
What are the official names of this protein?
Peroxisomal OPC-8:0-CoA ligase 1, 4-coumarate--CoA ligase isoform 9, At4CL9, 4-coumarate--CoA ligase-like 5.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: VE7_HPV12
Sequence: MIGKEVTVQDFTLELSELQPEVLPVDLLCEEELPNEQETEEESDIDRTVFKIIAPCGCSSCEVNLRIFVNATDTGIRTLQDLLISDLQLLCPECRGNCKHGGF
What is the function of this protein?
Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle.  Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication.  E7 protein has both transforming and trans-activating activities.  Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes.  Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation.  Also plays a role in the inhibition of both antiviral and antiproliferative functions of host interferon alpha.  Interaction with host TMEM173/STING impairs the ability of TMEM173/STING to sense cytosolic DNA and promote the production of type I interferon (IFN-alpha and IFN-beta).
What are the official names of this protein?
Protein E7.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E7 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=Predominantly found in the host nucleus.
Protein: RL19_TERTT
Sequence: MSSKNKIIQELENEQLKQELPEFSPGDTVVVQVKVTEGNRERLQAYEGVVIGIRNRGLNSAFTVRKISHGVGVERTFQTHSKQVESITVKRRGDVRQAKLYYLRELTGKAARIKEKLN
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: DYR_STAAS
Sequence: MTLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVVGVDVIHSIEDIYQLPGHVFIFGGQILFEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRKK
What is the function of this protein?
Key enzyme in folate metabolism.  Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
What are the official names of this protein?
Dihydrofolate reductase, DHFR.
What is the protein family that this protein belongs to?
Belongs to the dihydrofolate reductase family.