PharMolix/UniProtQA huggingface dataset:
Protein: RS2_SYNWW
Sequence: MSVVTMKQLLEAGVHFGHQTRRWNPKMATYIYMERNGIYIIDLQQTVKKFDAAYEFVKSVAAAGKGVLFVGTKKQAQETIREEASRCGMYFVNQRWLGGMLTNYKTIKRRVLRLKELEKQEAEGAFEVLSKKEVARLLNERERLERFLGGIKEMDKLPGAVFVVDPRKERIAVAEARKLNIPVVAIVDTNCDPDEIDYVIPGNDDAIRAVKLISSRIADAVLEGKQGEQITT
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: SRKA_SHIFL
Sequence: MNNSAFTFQTLHPDTIMDALFKQGIRVDSGLTPLNSYENRVYQFQDEERRRFVVKFYRPERWTADQILEEHQFALQLVNDEVPVAAPVAFNGQTLLNHQGFYFAVFPSVGGRQFEADNIDQMEAVGRYLGRMHQTGRKQLFIHRPTIGLNEYLIEPRKLFEDATLIPSGLKAAFLKATDELIAAVTAHWREDFTVLRLHGDCHAGNILWRDGPMFVDLDDARNGPAIQDLWMLLNGDKAQQRMQLETIIEAYEEFSEFDTAEIGLIEPLRAMRLVYYLAWLMRHWADPAFPKNFPWLTGEDYWLRQTATFIEQAKVLQEPPLQLTPMY
What is the function of this protein?
A protein kinase that phosphorylates Ser and Thr residues.  Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species.  Probably involved in the extracytoplasmic stress response.
What are the official names of this protein?
Stress response kinase A, Serine/threonine-protein kinase SrkA.
What is the protein family that this protein belongs to?
Belongs to the SrkA/RdoA protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LRC51_BOVIN
Sequence: MNKRNYMNTSVQEPPLDYSFRSIHVTQDLLSEEPRTGLRPVRHAKSGKSMTQSLWLNNNVLTDLRDFNHAVSQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEVNKLAALPRLRSLTLHGNPIEEEKGYRQYVLCTLPHITTFDFSGVTKADRTTAEVWKRMNIKPKKVRIKHNAL
What are the official names of this protein?
Leucine-rich repeat-containing protein 51.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_BACNA
Sequence: MNQWMELANRVLAGAEVTDEEALSILHCPDEDILLLMHGAFHIRKHFYGKKVKLNMIMNAKSGLCPENCGYCSQSAISKAPIESYRMVNKETLLEGAKRAHDLNIGTYCIVASGRGPSNREVDQVVDAVQEIKETYGLKVCACLGLLKPEQAKRLKDAGVDRYNHNLNTSQRNHSNITTSHTYDDRVNTVEIAKESGLSPCSGAIIGIKETKQDVIDIAKSLKALDADSIPVNFLHAIDGTPLEGVNELNPLYCLKVLALFRFINPSKEIRISGGREVNLRSLQPLGLYAANSIFVGDYLTTAGQEETEDHKMLSDLGFEVESVEEMKASLSAKS
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: CYB_GIRCA
Sequence: MINIRKSHPLMKIVNNALIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTPDTTTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFMHVGRGLYYGSYTFLETWNIGVILLFTVMATAFMEYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIIMALTMVHLLFLHETGSNNPMGIPSDMDKIPFHPYYTIKDILGALLLILVLMLLVLFTPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILIFMPLLHTSKQRSMMFRPFSQCLFWILVADLLTLTWIGGQPVEHPFIIIGQLASIMYFLIILVLMPVTSAIQNNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: HOIL1_DICLA
Sequence: MSLSSGGWTPTPGFTPDQSAALPTHYGASQSQLGCQTVLMSVRVSVCHSGIRPLCLPGAGDESLRLQLSMDPGKSGEFRLSLQDSSGTGRSVTIAEFDLGTVNYEVKSPKCHELSLVAPPHDRISFNFRCEQEAQEWATVVLSSLREAQRVAPQDNGPQRPLDGLNLQNTMILQRTEETCIELTRAIEAGDMQAASAFAATLARQHATLKIQPSAGEYEDTEISLAVVVEDSSSSCCVTVKVFPHMTTAALKQQMFLEYGFHPRVQRWVIGQCLCTDQRSLASYGVHQDGDTAFLYLLSARHARLTLQVLQQDQESALLLSSPSLSLPTPPLPATSANGPSSLDQRPYTTLPPRLHTSSSTERRNISEIKDLINLEMPQLNEALSPNTASTQGWSCPSCTYINKPTRPGCEICSTNRPENYIIPGGYRPDQLELRRIQQEKEAIRQYQQAREEERRENFARLVMMDSQDLLPNPEPVDCRICYMDLQPGEGVLLRECLHCFCRECLRSVIMLSEEPEVSCPYRDDTYSCACSLQEREIRALVPAEEYERWLQRGLSVAESRCEGSYHCATPDCLGWCVYEDTVNVFHCPVCRKHNCLICKSIHEGMNCKQYQDDLAARAINDSAARRTTQLLKTLVQSGEAMHCPQCGIIVQKRDGCDWLRCTVCHTEICWVTRGPRWGPKGPGDTSGGCRCNVNNQKCHPKCQNCH
What is the function of this protein?
Component of the LUBAC complex which conjugates linear ('Met-1'-linked) polyubiquitin chains to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation (By similarity).  LUBAC conjugates linear polyubiquitin to ikbkg and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways (By similarity).  Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation (By similarity).  LUBAC is recruited to the TNF-R1 signaling complex (TNF-RSC) to conjugate linear polyubiquitin to ikbkg and possibly other components contributing to the stability of the complex (By similarity).  The LUBAC complex is also involved in innate immunity by conjugating linear polyubiquitin chains at the surface of bacteria invading the cytosol to form the ubiquitin coat surrounding bacteria (By similarity).  LUBAC is not able to initiate formation of the bacterial ubiquitin coat, and can only promote formation of linear polyubiquitins on pre-existing ubiquitin (By similarity).  The bacterial ubiquitin coat acts as an 'eat-me' signal for xenophagy and promotes NF-kappa-B activation (By similarity).  Binds polyubiquitin of different linkage types (By similarity).
What are the official names of this protein?
RanBP-type and C3HC4-type zinc finger-containing protein 1, Heme-oxidized IRP2 ubiquitin ligase 1 homolog, HOIL-1, Heme-oxidized IRP2 ubiquitin transferase 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the RBR family.
Protein: MSPD3_HUMAN
Sequence: MRRGAPQDQELVGPGPPGRGSRGAPPPLGPVVPVLVFPPDLVFRADQRSGPRQLLTLYNPTGTALRFRVLCTAPAKYTVFDAEGYVKPQSCIDIVIRHVAPIPSHYDVQDRFRIELSEEGAEGRVVGRKDITSILRAPAYPLELQGQPDPAPRPGPPAGTPPPTARHFQEHPRQQLATSSFLLFLLTGIVSVAFLLLPLPDELGSQLPQVLHVSLGQKLVAAYVLGLLTMVFLRT
What are the official names of this protein?
Motile sperm domain-containing protein 3.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ZN268_HUMAN
Sequence: MATRVRTASIWVPPLQERNSSWDRIRKLQGQESILGQGTPGLQPLPGTPRQKQKSRRIEKVLEWLFISQEQPKITKSWGPLSFMDVFVDFTWEEWQLLDPAQKCLYRSVMLENYSNLVSLGYQHTKPDIIFKLEQGEELCMVQAQVPNQTCPNTVWKIDDLMDWHQENKDKLGSTAKSFECTTFGKLCLLSTKYLSRQKPHKCGTHGKSLKYIDFTSDYARNNPNGFQVHGKSFFHSKHEQTVIGIKYCESIESGKTVNKKSQLMCQQMYMGEKPFGCSCCEKAFSSKSYLLVHQQTHAEEKPYGCNECGKDFSSKSYLIVHQRIHTGEKLHECSECRKTFSFHSQLVIHQRIHTGENPYECCECGKVFSRKDQLVSHQKTHSGQKPYVCNECGKAFGLKSQLIIHERIHTGEKPYECNECQKAFNTKSNLMVHQRTHTGEKPYVCSDCGKAFTFKSQLIVHQGIHTGVKPYGCIQCGKGFSLKSQLIVHQRSHTGMKPYVCNECGKAFRSKSYLIIHTRTHTGEKLHECNNCGKAFSFKSQLIIHQRIHTGENPYECHECGKAFSRKYQLISHQRTHAGEKPYECTDCGKAFGLKSQLIIHQRTHTGEKPFECSECQKAFNTKSNLIVHQRTHTGEKPYSCNECGKAFTFKSQLIVHKGVHTGVKPYGCSQCAKTFSLKSQLIVHQRSHTGVKPYGCSECGKAFRSKSYLIIHMRTHTGEKPHECRECGKSFSFNSQLIVHQRIHTGENPYECSECGKAFNRKDQLISHQRTHAGEKPYGCSECGKAFSSKSYLIIHMRTHSGEKPYECNECGKAFIWKSLLIVHERTHAGVNPYKCSQCEKSFSGKLRLLVHQRMHTREKPYECSECGKAFIRNSQLIVHQRTHSGEKPYGCNECGKTFSQKSILSAHQRTHTGEKPCKCTECGKAFCWKSQLIMHQRTHVDDKH
What is the function of this protein?
Contributes to cervical carcinogenesis in part through the TNF-alpha-induced NF-kappa-B signaling pathway by interacting with the I-kappa-B-kinase (IKK) core complex.
What are the official names of this protein?
Zinc finger protein 268, Zinc finger protein HZF3.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
[Isoform 1]: Nucleus. SUBCELLULAR LOCATION: [Isoform 2]: Nucleus. Cytoplasm.
Protein: ADT3_PIG
Sequence: MTEQAISFAKDFLAGGIAAAISKTAVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKHTQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKSATEREFKGLGDCLVKITKSDGIRGLYQGFNVSVQGIIIYRAAYFGVYGTAKGMLPDPRNTHIVVSWMIAQTVTAVAGVFSYPFDTVRRRMMMQSGRKGADIMYKGTLDCWRKIFKDEGGKAFFKGAWSNVLRGMGGAFVLVLYDELKKVI
What is the function of this protein?
ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell (By similarity).  Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane (By similarity).  In addition to its ADP:ATP antiporter activity, also involved in mitochondrial uncoupling and mitochondrial permeability transition pore (mPTP) activity (By similarity).  Plays a role in mitochondrial uncoupling by acting as a proton transporter: proton transport uncouples the proton flows via the electron transport chain and ATP synthase to reduce the efficiency of ATP production and cause mitochondrial thermogenesis.  Proton transporter activity is inhibited by ADP:ATP antiporter activity, suggesting that SLC25A6/ANT3 acts as a master regulator of mitochondrial energy output by maintaining a delicate balance between ATP production (ADP:ATP antiporter activity) and thermogenesis (proton transporter activity).  Proton transporter activity requires free fatty acids as cofactor, but does not transport it (By similarity).  Also plays a key role in mPTP opening, a non-specific pore that enables free passage of the mitochondrial membranes to solutes of up to 1. 5 kDa, and which contributes to cell death (By similarity).  It is however unclear if SLC25A6/ANT3 constitutes a pore-forming component of mPTP or regulates it (By similarity).
What are the official names of this protein?
ADP/ATP translocase 3, ADP,ATP carrier protein 3, Adenine nucleotide translocator 3, ANT 3, Solute carrier family 25 member 6.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Note=The complex formed with ARL2BP, ARL2 and SLC25A6/ANT3 is expressed in mitochondria (By similarity). May localize to non-mitochondrial membranes (By similarity).
Protein: COX16_ASPCL
Sequence: MPVFQAKTFRRATTASSSLGERIGAAYRGGLPKHPFLLFGLPFIMVIVAGSFVLTPAAALRYERYDRKVKQLSQEEAMELGLKGPDGEEGIRRNPRRRILGDEREEYYRLMAKDLDNWEQKRVQRFKGEPDGKL
What is the function of this protein?
Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase.  May participate in merging the COX1 and COX2 assembly lines.
What are the official names of this protein?
Cytochrome c oxidase assembly protein cox16, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the COX16 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: EFG_CERS5
Sequence: MAREYPLELYRNFGIMAHIDAGKTTTTERILFYTGKSHKLGEVHDGAATMDWMEQEQERGITITSAATTTFWERTEDGKTPQTPKHRFNIIDTPGHVDFTIEVERSLAVLDGAVCLLDANAGVEPQTETVWRQADRYKVPRIVFVNKMDKIGADFFNCVKMIKDRTGATPAPIALPIGAEDKLEGIIDLVTMKEWVYQGEDLGASWIIKDIRDELQAEAEEWRGKLIELAVEQDDEAMEAYLEGNEPDVPTLRALIRKGCLSMSFVPVTAGSAFKNKGVQMVLNSVIDYLPSPLDVPAYMGFAPGDETETRNIPRSADDAQPFAALAFKIMNDPFVGSLTFTRLYSGVLKKGDQMVNSTKGKRERVGRMMMMHAINREEIDEAFAGDIIALAGLKETTTGDTLCDPANQVVLETMTFPEPVIEIAVEPKTKADQEKMGLALARLAAEDPSFRVETDFESGQTIMKGMGELHLDILVDRMKREFKVEANIGAPQVAYRETISRAAEIDYTHKKQTGGTGQFARVKLQIDPTEPGQGYSFESKIVGGAVPKEYIPGVEKGIKSVMDSGPLAGFPVIDFKVALIDGAFHDVDSSVLAFEIAARAAMREGLKKAGAKLLEPIMKVEVVTPEEYTGGIIGDLTSRRGMVQGQDTRGNANVINAFVPLANMFGYINTLRSMSSGRAVFSMHFDHYDAVPQNISDEIQKKYA
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU_NITHX
Sequence: MAKAKFERNKPHCNIGTIGHVDHGKTSLTAAITKVLAEAGGATFTAYDQIDKAPEEKARGITISTSHVEYETPNRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLARQVGVPAIVVFLNKCDMVDDPELLELVEMEVRELLSKYDFPGDDIPIIKGSALAVLENSDPKLGHDAVLELMKAVDAYIPQPERPVDQPFLMPVEDVFSISGRGTVVTGRVERGIVKVGEEIEIVGIRPTQKTTVTGVEMFRKLLDQGQAGDNIGALLRGTKREDVERGQVLCKPGSVKPHTKFKAEAYILTKEEGGRHTPFFTNYRPQFYFRTTDVTGVVHLPAGTEMVMPGDNVAMEVHLIVPIAMEEKLRFAIREGGRTVGAGVVASIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_WOLTR
Sequence: MPKKVFCGVVTKAKCDKTVKVSVLRVYKDKLYKKVIKRYKEYTVHDENNSCKEGDKVFIQEHRPISATKKWVIVRVE
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: HSCB_AZOSB
Sequence: MAIDLQQDYFSLFGMPRRFRIDESALEAAWHGLQGEVHPDRFAHLPDVEKRRSMQWATRVNEGFRVLRKPLSRAQYLLELAGVDAAIDTNTAMSPEFLMEQMEWREAVEEARAAGEVDELEQLHLRLRQHSREVHAGLADALDDAGDYPAAAETVRRLMFIEKLQHEIDDALEALEN
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB homolog.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: PCP_STRPC
Sequence: MKILVTGFDPFGGEAINPALEAIKKLPATIHGAEIKYIEVPTVFQKSADVLQQHIESFQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPIRADGKAAYFSTLPIKAMVAAIHQAGLPASVSNTAGTFVCNHLMYQALYLVDKYCPNAKAGFMHIPFMMEQVVDKPNTAAMNLDDITRGIEAAIFAIVDFKDRSDLKRVGGATH
What is the function of this protein?
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
What are the official names of this protein?
Pyrrolidone-carboxylate peptidase, 5-oxoprolyl-peptidase, Pyroglutamyl-peptidase I, PGP-I, Pyrase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AVH6_PHYSP
Sequence: MRLSSTTFVVLAAVLLASGTAVSKADETGVTNVNAVHSPNVLAGVDKRFLRSHHTEDGEAKLSNYDNEERNGLFGANTLSNMGKDTILRFQMFTKWKANGYLPKKIKDDIPRSLYKAYKIHYRMN
What is the function of this protein?
Effector that suppresses plant defense responses during the early stages of pathogen infection.  Suppresses cell death induced by effectors and PAMPs in plant hosts (PubMed:23550527).  Triggers a hypersensitive response (HR) in the presence of Rps1d (PubMed:23550527, PubMed:23594349).  Suppresses BAX-induced cell death and enhan,ced P. capsici infection in Nicotiana benthamiana.  Also suppresses effector-triggered immunity induction by associating with Avr1b and Rps1b, suggesting a role in suppressing plant immunity (PubMed:23594349).
What are the official names of this protein?
RxLR effector protein Avh6, Avirulence homolog protein 6, Avirulence protein 1d.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cell.
Protein: Y4042_BURM9
Sequence: MCHAREASPGTGEPEAAPRDNFPRAAGSKRGVGAAFETRAQRFLERAGLALVARNVTVRGGEIDLVMRERDGTLVFVEVRARANSRYGGAAASIGVRKRMRLLLAAHAFWARTGGANACRFDVVAFEGGRLVWLRDAFRADDAG
What are the official names of this protein?
UPF0102 protein BMA10229_A1742.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: FGOP2_XENLA
Sequence: MSCTIEKVLADAKELVERLREHDGAAESLIEQTTTLNKRVEAMKQYQEEVQELNEIARHRPRSTLVLGIQQENRQIRQLQHENKELRTSLKEHQSALELIMSKYREQMFRLLMASKKDDPGVIMKLKEQHSKELQAHIEKINEMTAVMRRAIEMDEQRGDREHNRIIKLEQENKRLREILQITKISFLNLHKEDASENSPHSAPVPNTDLILRKS
What are the official names of this protein?
FGFR1 oncogene partner 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the SIKE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN423_RAT
Sequence: MSRRKQAKPRSVKVEEGEASDFSLAWDSSVAAAGGLEGESECDRKSSRALEDRNSVTSQEERNEDDEDVEDESIYTCDHCQQDFESLADLTDHRAHRCPGDGDDDPQLSWVASSPSSKDVASPTQMIGDGCDLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTFCSRLFKHKRSRDRHIKLHTGDKKYHCHECEAAFSRRDHLKIHLKTHSSSKPFKCSVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTLHPQLSEKADLQCIHCPEVFVDESTLLAHIHQAHANQKHKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASMSSATPDSTPDPVLGSVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQSWSKVVYSCPYCSKRDFTSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKSHAYPVMQFGNISAFHCNYCPEMFADINSLQEHIRVSHCGPNANPPDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSTKLESPVIQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSGSANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCHITTHSKKYNCRFCSKAFHAVLLLEKHLREKHCVFDPAAENGTANGVPPTSTKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQDLVRLDVNGLPYGLCAGCMARSANGQVGGLAPPEPADRPCAGLRCPECNVKFESAEDLESHMQVDHRDLTPETSGPRKGAQTSPVPRKKTYQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTELQNHTMSQHAQ
What is the function of this protein?
Transcription factor that can both act as an activator or a repressor depending on the context.  Plays a central role in BMP signaling and olfactory neurogenesis.  Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes.  Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved in terminal olfactory receptor neurons differentiation; this interaction preventing EBF1 to bind DNA and activate olfactory-specific genes.  Involved in olfactory neurogenesis by participating in a developmental switch that regulates the transition from differentiation to maturation in olfactory receptor neurons.  Controls proliferation and differentiation of neural precursors in cerebellar vermis formation.
What are the official names of this protein?
Zinc finger protein 423, Olf1/EBF-associated zinc finger protein, rOAZ, Smad- and Olf-interacting zinc finger protein.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL21_DELAS
Sequence: MYAVIKTGGKQYRVAAGEKIKVEQIAADVGQEVVIDQVLAVGNGAEIKVGTPLVSGASVKATVVAHGKHDKVHIFKMRRRKHYQKRQGHRQQFTELQIVAIAA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: FAEHP_METTH
Sequence: MYRIGEALIGSGNEVAHIDLIIGDKEGNAGAAFANGLTNLSLGHTPLLSVVRPNLMTKPATLIVPKVTVSCLEDADKVFGPAQTAVARAVADSVEEGIIPEEKAEDLVVIVSVFIHPEAEDYRKIYQYNYGATKLALRRAMEGYPSVRKVLSEKDRGSHPIMGFRAVRLWNPPYLQVALDLDSMEEMERIINTLPDRERILLEAGTPLVKKFGVGVVRRIRELRRDAFIIADLKTLDVGRIEVKMAADETADAVAISGLGTVESIEKAIHEAQKQGIYSILDMMNVENFVDKLRGLKYKPDIVLLHRNVDLETLRAERGEELGEMSEWGNIREIKEILGPRGLVAVAGGITPSKMQEALDSGADIIVVGRYIIGSRDVRRAAEDFLEHMPQDPDTMRLPLDEDEAI
What is the function of this protein?
Catalyzes the reversible formation of ribulose-5-phosphate and formaldehyde from 3-hexulose-6-phosphate.
What are the official names of this protein?
Bifunctional enzyme Fae/Hps.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily.
Protein: ISPF_LISMC
Sequence: MIRIGQGYDVHKLAYDRELIVGGIKIPYEKGLLGHSDADVLLHAITDAIIGAIGAGDIGHFFPDTDMAFKDADSAELLEEIWQKVEADGFRLGNLDATIIAEKPKMAPYVEQMKLRIAELLHADSAQVNVKATTTEKLGFTGRKEGIASLAVVLLEK
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: HIS3_THIDA
Sequence: MSDWLDAVKWDAQGLVPAIAQDAASGEILMVAWMNREALEETARTGRGVYFSRSRHKLWRKGEESGHVQTVSEIRLDCDNDVILLKIEQLGGIACHTGRRSCFFHKLTTDDRGHADWVATEPVLKNPDEIYRR
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_STRPS
Sequence: MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEAAFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: MURA_COLP3
Sequence: MDAFKVIGGKPLRGDVVISGAKNAALPILMSALLSKTPVVFSNVPQLNDILTTVKLLGQLGAKTKWLNEEKLMIDASSIDVCRAPYDLVKTMRASILVLGPLLARMGHAEVSLPGGCAIGARPVNLHIQGLKLMGADITVEDGYIVAKKQGRLTGATIFMDTVSVTGTENLMMAAALAEGITIIENAAREPEIVDLANCLISMGAKITGAGTDTLTIEGVSELCGKEYSVMPDRIETGTFLVAAAVTQGHIKCLNTDPSSLEAVLSKLQEAGATITTGDDWIELEMSAPAKAVNVRTAPHPAFPTDMQAQFMTMNVLAEGTATVIETIFENRFMHVPELQRMGADIALEGNTAIVKGVASLNGAQVMATDLRASASLVIAGLVAKSPTQVDRIYHIDRGYLCIEGKLQSLGADITRIKVD
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.