PharMolix/UniProtQA huggingface dataset:
Protein: DAM1_SCHPO
Sequence: MEKYQKATQNPLENVDNVKIESENAIPSNLQAFTKSLAVLDDNVSEFRKRMNHLSATKQILDNFNESFSSFLYGLQINAFCVDYENAPLSESFLLQAKKDQFKATLMTRTGHSISDPPYDGGVISHDPNFATADETFATNDTSFIERPETYSASR
What is the function of this protein?
Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation.  The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore.
What are the official names of this protein?
DASH complex subunit dam1, Outer kinetochore protein dam1.
What is the protein family that this protein belongs to?
Belongs to the DASH complex DAM1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Associates with the mitotic spindle and the kinetochore. Kinetochore association occurs only during mitosis.
Protein: LPXB_ECO24
Sequence: MTEQRPLTIALVAGETSGDILGAGLIRALKEHVPNARFVGVAGPRMQAEGCEAWYEMEELAVMGIVEVLGRLRRLLHIRADLTKRFGELKPDVFVGIDAPDFNITLEGNLKKQGIKTIHYVSPSVWAWRQKRVFKIGRATDLVLAFLPFEKAFYDKYNVPCRFIGHTMADAMPLDPDKNAARDVLGIPHDAHCLALLPGSRGAEVEMLSADFLKTAQLLRQTYPDLEIVVPLVNAKRREQFERIKAEVAPDLSVHLLDGMGREAMVASDAALLASGTAALECMLAKCPMVVGYRMKPFTFWLAKRLVKTDYVSLPNLLAGRELVKELLQEECEPQKLAAALLPLLANGKTSHAMHDTFRELHQQIRCNADEQAAQAVLELAQ
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: BET11_ARATH
Sequence: MNPRREPRGGRSSLFDGIEEGGIRAASSYSHEINEHENERALEGLQDRVILLKRLSGDINEEVDTHNRMLDRMGNDMDSSRGFLSGTMDRFKTVFETKSSRRMLTLVASFVGLFLVIYYLTR
What is the function of this protein?
Required for vesicular transport from the ER to the Golgi complex.  Functions as a SNARE associated with ER-derived vesicles (By similarity).
What are the official names of this protein?
Bet1-like SNARE 1-1, AtBET11, Bet1/Sft1-like SNARE 14a, AtBS14a.
What is the protein family that this protein belongs to?
Belongs to the BET1 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type IV membrane protein. Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Protein: SPA3L_RAT
Sequence: MAFIAALGLLMAGICPAVLCDGTLGRDTLSHEDHGKGRQLHSLTLASSNTDFALSLYKKLALRNPDKNVVFSPLSISAALTILSLGAKDSTMEEILEGLKFNLTEITEEEIHQGFGHLLQRLSQPEDQVEINTGSALFIDKEQPILSEFQEKTRALYQAEAFIADFKQPNEAKKLINDYVSNQTQGKIAELFSDLEERTSMVLVNYLLFKGKWKVPFNPNDTFESEFYLDEKRSVKVPMMKIKEVTTPYVRDEELSCSVLELKYTGNASALFILPDQGKMQQVESSLQPETLKKWKDSLIPRIINDLRMPKFSISTDYSLKEVLPELGIKKVFSQQADLSRITGTKDLYVSQVVHKAVLDVDETGTEATAATGVATVIRRQPRTLNFNRPFMVVITDMDSQSILFVAKITNPK
What are the official names of this protein?
Serine protease inhibitor A3L, Serpin A3L, CPI-23, Contrapsin-like protease inhibitor 3, Serine protease inhibitor 1, SPI-1.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GATC_TRIAD
Sequence: MAVKPSANLGKAFQLPHPFNSCVYIQIPPQPTWSINEYWERNPNKQYLDESDTTYLEELTLTPIEKHQALEKLNTIISAADRLQEVDTKNVDPMYTCVDEREMYMNSGQDGETVNKEEILGNAHKIFQDYFTAPTSEKMRSSSDLNAKE
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial, Glu-AdT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: EFHC2_DANRE
Sequence: MALPMLPGNSVNRNLGKDKFHKSQHFDYSNGVAMMVGTEKPGIGGDLLLGQSARAKYSRFPKGEGSGAPAWLAFDKQVLCFDAYFNEAVPQRREEKYRVRKCKIYFYLEDDTIQVVEPEFKNSGIPQGTLIRRHRIPLPAPKDDCFYNVHHFNINQEVLFYSRNFMITDCDPFTRNFLVKMGVRLNPPASTPADPYTTLRQELEENMKPLRPYERLDTLKQFLEHDRQVLRFYCYWDDSESMFGDPRELILHYFLADDTMEMYEVVPPNSGRDTVPKFLHRGKLPKHAPIPKRQPGEITDRTVLNVFGPVGQGGPYILDSLKTGALEEEFYKDSDLTIGAVINVWGRRVLICDCDYFTKEYYRSKYGIEDFPSISYKASPPPKPAKQVPPYTGFGSEEDSLCSCQGLLPKPPQKDFKKLMEKDRRGLVSNVLRFVGKMLTDSPVDKERVFIICFYLTDDTIAVFEPPQRNSGVIGGKFLERGRVKKPGQELFKSEMSEYFTAQDLYVGAHLLLNSQPFQLVDADDFTFSYMEQHADEFPKANIGTIISKVKSISEEQQKTVKQFFTMSDPSSTGSLPYESFRTLLADLDVELSEHEIMTLGRVYSVRQQPEVNVGLMLAVAQDHLKKKNFEKFSEMIQAFTHEDRDRCGQLSSKEARIICKAFRLPLSDDLLRALLEKFAGESEKIDYHAFLSGINWRENPVPAVLPEDTVKFDADWRGEAPEPAVKTINYSLLLEDVFGSATNINDS
What is the function of this protein?
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.
What are the official names of this protein?
EF-hand domain-containing family member C2.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme.
Protein: MRAY_STRT2
Sequence: MTMSLIAGVAAFVLTVLAMPHFITYYKIKKIGGQQMHEDVKQHLAKAGTPTMGGTVFLVVAILISLIFNFHVFTEGHPAYGATAGILFVILIYGIIGFLDDFLKIFHQINEGLKPWQKMALQIVAGLLFYFIHVLPSGTNSLAIGGLTIQLGVFYVLFVLFWIVGFSNAVNLTDGIDGLASVSVVISLIAYGIIAFVKGELAILTIIITMIGALLGFFVFNHKPAKVFMGDVGSLSLGAMLAVISIALRVEWTLLLIGVVYVLETASVMLQVSYFKYTKRKYGEGRRIFRMTPFHHHLELGGISGKGEKWSEWKVDAFLWTIGALASSITLWMVLGNVMK
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LECR_CLAKE
Sequence: ANSNSRPHLLQTQKPFSVVLAISITFYLLLLNKVNSEEALSFTFTKFVSNQDELLLQGDALVSSKGELQLTRVENGQPIPHSVGRALYSDPVHIWDSSTGSVASFVTSFTFVVEAPNENKTADGIAFFLAPPDTQVQSLGGFLGLFNSSVYNSSNQILAVEFDTFSNSWDPTARHIGIDVNSIESTRTATWGWRNGEVAIVLITYVAPAETLIASLTYPSSQTSYILSAAVDLKSILPEWVRVGFSAATGRSAGYVETHDVLSWSFTSTLETGNSGAKQNNAHLASYALI
What is the function of this protein?
Does not have any carbohydrate binding or agglutination activity.
What are the official names of this protein?
Lectin-related protein, CLLRP, LRPCL.
What is the protein family that this protein belongs to?
Belongs to the leguminous lectin family.
Protein: PMA10_ARATH
Sequence: MAEDLDKPLLDPDTFNRKGIDLGILPLEEVFEYLRTSPQGLLSGDAEERLKIFGPNRLEEKQENRFVKFLGFMWNPLSWVMEAAALMAIALANSQSLGPDWEDFTGIVCLLLINATISFFEENNAGNAAAALMARLALKTRVLRDGQWQEQDASILVPGDIISIKLGDIIPADARLLEGDPLKIDQSVLTGESLPVTKKKGEQVFSGSTCKQGEIEAVVIATGSTTFFGKTARLVDSTDVTGHFQQVLTSIGNFCICSIAVGMVLEIIIMFPVQHRSYRIGINNLLVLLIGGIPIAMPTVLSVTLAIGSHRLSQQGAITKRMTAIEEMAGMDVLCCDKTGTLTLNSLTVDKNLIEVFVDYMDKDTILLLAGRASRLENQDAIDAAIVSMLADPREARANIREIHFLPFNPVDKRTAITYIDSDGKWYRATKGAPEQVLNLCQQKNEIAQRVYAIIDRFAEKGLRSLAVAYQEIPEKSNNSPGGPWRFCGLLPLFDPPRHDSGETILRALSLGVCVKMITGDQLAIAKETGRRLGMGTNMYPSSSLLGHNNDEHEAIPVDELIEMADGFAGVFPEHKYEIVKILQEMKHVVGMTGDGVNDAPALKKADIGIAVADATDAARSSADIVLTDPGLSVIISAVLTSRAIFQRMRNYTVYAVSITIRIVLGFTLLALIWEYDFPPFMVLIIAILNDGTIMTISKDRVRPSPTPESWKLNQIFATGIVIGTYLALVTVLFYWIIVSTTFFEKHFHVKSIANNSEQVSSAMYLQVSIISQALIFVTRSRGWSFFERPGTLLIFAFILAQLAATLIAVYANISFAKITGIGWRWAGVIWLYSLIFYIPLDVIKFVFHYALSGEAWNLVLDRKTAFTYKKDYGKDDGSPNVTISQRSRSAEELRGSRSRASWIAEQTRRRAEIARLLEVHSVSRHLESVIKLKQIDQRMIRAAHTV
What is the function of this protein?
The plasma membrane H(+) ATPase of plants and fungi generates a proton gradient that drives the active transport of nutrients by H(+)-symport.  The resulting external acidification and/or internal alkinization may mediate growth responses.
What are the official names of this protein?
ATPase 10, plasma membrane-type, Proton pump 10.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NUOI_EHRRW
Sequence: MINKRSLLASFINLPYSLFITFKGMYITLRYMFKPKVTLNYPLEKNPLSTRFRGEHALRTYKNGEERCIACKLCEAICPAQAITIEAQERDTDNSRRTVRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEYATETREELMYNKSKLLHNGQIWEEAIDLRIKKNSKFY
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MURG_LEGPA
Sequence: MSPSIVFTGGGTAGHVTPNIALIKEFRKEGWNVEYIGSVSGIEKEMIEPLDIPFHGVSSGKLRRYFSLKNLLDPFKIVLGIIQSSLLFYKIKPDVVFSKGGFVAFPVVVGAWLNRIPVVAHESDMSPGLANRLSFPFVNKICLTFDAGKKYFKRQDKIEVTGTPIRQQLLTGNRMKGLELCGFNSSKPCLLVVGGSLGAGSINSCIRSALKQLTSEFQVIHLCGKGKLDSSLVGVEGYCQFEYANEELADLFAASSVVISRAGANSLYEILALGKPHILIPISSQVSRGDQIQNARYFQGLGISVVIQDELLKADVLLQAVQDVMRKKDEIDNKIKALKIESATDKIVAIIKEQAHVQTPRIV
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SYY_BORBZ
Sequence: MNLALSLLHKRGFLKQCTSLKVLSDLMDREKIVFYAGVDATSSSLHIGHLIPFLAMMHLRQHGHMPIVLIGDSTAKIGDPSGKSEMRKILSSEEIGNNALLIKNQLQRITKFTSECFIHNSNWLDNLNYIEFLRDVGMHFSVNRMLSFETYKRRMDFGLSFIEFNYQLLQSYDYYMLNKIKNCRLQIGGDDQWGNIISGVDLIRKKNGSETFGLTFPLITRSDGKKMGKSEKGAVYLDSNLFSIYDFYQYFRNTSDSDVKTFLYLFTFLEEDEIELISNFKGNSLNKAKEILAFEITKIVHGEAEALKVQEASFAAFRGSGDRSNIPFFKFSFSSLKEEILLVDLMLDSKIVPSKSEGRRLIDSGGVYINGKRVESQSHLLTKKDFNNNEVELRVGKKKFLRIVI
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PP224_ARATH
Sequence: MSEASCLASPLLYTNSGIHSDSFYASLIDSATHKAQLKQIHARLLVLGLQFSGFLITKLIHASSSFGDITFARQVFDDLPRPQIFPWNAIIRGYSRNNHFQDALLMYSNMQLARVSPDSFTFPHLLKACSGLSHLQMGRFVHAQVFRLGFDADVFVQNGLIALYAKCRRLGSARTVFEGLPLPERTIVSWTAIVSAYAQNGEPMEALEIFSQMRKMDVKPDWVALVSVLNAFTCLQDLKQGRSIHASVVKMGLEIEPDLLISLNTMYAKCGQVATAKILFDKMKSPNLILWNAMISGYAKNGYAREAIDMFHEMINKDVRPDTISITSAISACAQVGSLEQARSMYEYVGRSDYRDDVFISSALIDMFAKCGSVEGARLVFDRTLDRDVVVWSAMIVGYGLHGRAREAISLYRAMERGGVHPNDVTFLGLLMACNHSGMVREGWWFFNRMADHKINPQQQHYACVIDLLGRAGHLDQAYEVIKCMPVQPGVTVWGALLSACKKHRHVELGEYAAQQLFSIDPSNTGHYVQLSNLYAAARLWDRVAEVRVRMKEKGLNKDVGCSWVEVRGRLEAFRVGDKSHPRYEEIERQVEWIESRLKEGGFVANKDASLHDLNDEEAEETLCSHSERIAIAYGLISTPQGTPLRITKNLRACVNCHAATKLISKLVDREIVVRDTNRFHHFKDGVCSCGDYW
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At3g12770.
What is the protein family that this protein belongs to?
Belongs to the PPR family. PCMP-H subfamily.
Protein: LCE4A_HUMAN
Sequence: MSCQQNQQQCQPPPKCPIPKYPPKCPSKCASSCPPPISSCCGSSSGGCGCCSSEGGGCCLSHHRHHRSHCHRPKSSNCYGSGSGQQSGGSGCCSGGGCC
What is the function of this protein?
Precursors of the cornified envelope of the stratum corneum.
What are the official names of this protein?
Late cornified envelope protein 4A, Late envelope protein 8, Small proline-rich-like epidermal differentiation complex protein 4A.
What is the protein family that this protein belongs to?
Belongs to the LCE family.
Protein: SOXA_RHOSU
Sequence: MKTMTGRLVAAALVCGGAFSGAAVSAGPDDPLVINGEIEIVTRAPTPAHLADRFDEIRSGWTFRTDDTQALEMDDFENSGMVFVEEARAVWDRPEGTEGKACADCHGAVDDGMYGLRAVYPKYVESAGKVRTVEQMINACRTSRMGAPEWDYIGPDMTAMVALIASVSRGMPVSVAIDGPAQSTWEKGREIYYTRYGQLDLSCASCHEQYFDHYIRADHLSQGQINGFPSYRLKNARLNAVHDRFRGCIRDTRGVPFAVGSPEFVALELYVASRGNGLSVEGPSVRN
What is the function of this protein?
C-type diheme cytochrome, which is part of the SoxAX cytochrome complex involved in sulfur oxidation.  The SoxAX complex catalyzes the formation of a heterodisulfide bond between the conserved cysteine residue on a sulfur carrier SoxYZ complex subunit SoxY and thiosulfate or other inorganic sulfur substrates.  This leads to the liberation of two electrons, which may be transferred from the SoxAX complex to another cytochrome c and which then may be used for reductive CO(2) fixation.
What are the official names of this protein?
L-cysteine S-thiosulfotransferase subunit SoxA, Cytochrome c551 subunit diheme, Protein SoxA, SoxAX cytochrome complex subunit A, Sulfur oxidizing protein A, Thiosulfate-oxidizing multienzyme system protein SoxA, TOMES protein SoxA.
What is the protein family that this protein belongs to?
Belongs to the SoxA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RS7_FRATF
Sequence: MSRRNRAPKRDILPDPKYKSQVVAKFVNHIMLSGKKSIAEKIVYGAFDKIKAKDASANEVEVFEKALESVSPMVEVKSRRVGGATYQVPVEVRPERRQTLGMRWIIDAARKRKENTMGDRVAAEILEAVEGRGAAVKKREDTHKMAEANKAFAHFRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: PANC_SALPA
Sequence: MLIIETLPLLRQHIRRLRQEGKRVALVPTMGNLHDGHMKLVDEAKARADVVIVSIFVNPMQFDRPDDLVRYPRTLQEDCEKLNKRKVDYVFAPAVEEIYPQGLEGQTYVDVPGLSTMLEGASRPGHFRGVSTIVSKLFNLIQPDIACFGEKDFQQLALIRKMVADMSYDIEIVGVPIIRAKDGLALSSRNAYLTAEQRKIAPGLYNVMNSIAEKLIAGNRELQEIIAIAEQELNEKGFRADDIQIRDADTLLELTETSKRAVILAAAWLGQARLIDNQSVTLAQ
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBK_HORVU
Sequence: MPNILSLTCICFNSVLYPTSFFFAKLPEAYAIFNPIVDIMPVIPLFFFLLAFVWQAAVSFR
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein K, PSII-K.
What is the protein family that this protein belongs to?
Belongs to the PsbK family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single- pass membrane protein.
Protein: MBLK1_APIME
Sequence: MADCPYARCIQERRHIRRELLRWTKNMVFVVGLERVAEELMGRRRWKQYQDTLYSGTRSSESLTAQAHHRLYPAFSSSCDPVPGNLEQIGSRPLHPPASSTSLPATITTTTTTTTTTTATAAATATTTATGLIKQETLQRHHHLQNHHHHLQSTAVQDHHRPYQQQQQQQQRQQQRQEERRLRPDEIKVEVGEDEFANGGAARDESKAGSTDASTPATVTTTGATTTLPAASATGTGPATPSAVVATSNATAAMTTGTTTIPTRRLRKRRQNDGEGADDRDDDEENEEEEDGRGQSEAEKRLKLDEDADGAVSPLRREKDRGSREYPTSNATDTDGTKERTEEVALDRTPVTQGLLRVKKEEELQEAPSCGGGPTILTTPGLDSDGIRLPCREVEAAATARNVVAPFLIGSRRTSPPPEDWKPLDKCYFCLDGKLPHDDQPPLSPQSDSSSSSRSAESPMSVQVDPMAASVVAAALTGTYPTLLPQWCLPPREAPLVGVQPHQDSATPADQPLDLSAKPKNSQDNNISLLEQQKIPLRMTAGIDPKSIFNSGYRPKPRMSGPVAAVAAAAVAAAGVGGVPVVGAGGGRRAYTEEELQAALRDIQSGKLGTRRAAVIYGIPRSTLRNKVYKLAMERERDASLSSTHSHPHEPGAPATTITTITTTTTTTTTTTTTTTTPNTTQNASATTPPPQVDEVDDKELSGAEEEKEVEKALLKPLLSLEDLVRFSTLEGSGGDSLRTLLQRGQETGAEWPGLEHANIGPYIQKMIAAAAPFKGMETQDYRIPEVMRRLMSEDKRLSKSVNGDQSQPPHQQLHHHQSTHPQAQAQAQPQQQQQQQQQQPQQQQQQQQQQQQQQRGPMTNDDFNPNIEEEASDSAQGRAILKIPSYKPASTPGCSSKNGEPTSAAFAQGFATAASSPGLLERASPAFSGTSSPTNSLVGKTVAVNFRDVIAKSISVKFQEGQTVSGGGMGGCQPGGVVQSQQPIMTDPSPFKRGRYTPPQPANAQQGQAQAQAKPQSQEANKPKPATGGKGTRPKRGKYRNYDRDSLVEAVRAVQRGEMSVHRAGSYYGVPHSTLEYKVKERHLMRPRKRDQKQSDDKTKETSTVTAAAAATNIRPGTADNKPQLKPQKPFTSPGGIPGPNGIKMPSFMEGMPHLPFTPFNFWNPPPFMPSPFMAGAPNVPTILPEQYFATSRIRGLQEQQRNAAMVQQQQQQQQQQQQQQQQQQQQQQQQQHQAREREGVGAGIAETSAGTSNSRGAAQMSKVPRDVSEGIYDGSGANGSFLDNLIRSSLETGIPRDQRAMTEARNQQQQASSQQQIPESMRSKALIDQLCRNSRRTPVPRLAQDSSEDESYRGPSASGGRPVPERPERVPTVDLSPSPSDRGRNDDGSDRLTSPPTPLSISRAGSRDEDSTRDSTKLDRSSREREVHNGGQQEDRDRKTLTSAPQQPQQQQQQQQQQQQQQQQLNHYPDLHNLYAVPTDKKSACDSKLIVDHSSQKTQQQQPQQQQQQQQQQQPQQQSQQPQQQQPQPQQQQQQQQQQQPQQQQKEYGAVSGLVVQLQRGYNSGNNRSGEQANSQQQQQQQSGEPVIGMEDSVEQ
What is the function of this protein?
Transcriptional activator which binds to the consensus sequence 5'-CCCTATCGATCGATCTCTACCT-3'.  May play a role in higher-order sensory processing.
What are the official names of this protein?
Mushroom body large-type Kenyon cell-specific protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: UL150_HCMVM
Sequence: MLTLYLFTATCCFVCALPRQAQVDTAICHHTWPMCSDVPHPTSSAHNTALSSSHAISIEHRLLHSPSPPRENIRHSMRCRRRAIASSASTPVSHTQPLAANHRRSRITYATTDPTNSPTASPAKSDKLEADADPALHRRPDSLLRHLFQPCHAQRGTSNRATSQRASLNAVHHKLCGAMISSSWSTTCTPAIMDLPSLSVELSAGHKKKETPTEGGWGGEEGEDDVLATIRNTLSAPTSPAAATTHRLSFPEGSSFCLTAVSEYSQRLTSTAALTPPPPAVAAPFSFSSTVSETGAFPQSTAGRTRVDDTAVVTAGDPRSPVTHVTLLQIFRLRSSLLTSRSGDTLRGGEHEAIPKVASLFWTLLKATQTVEITHKTPSADSHRNPQKYTDRPQRLLLTALAIWQRTYNNTRADHAPQVRLLGNILTYRRPQTATASAKAHTQQQPEEPKGQQIWAQTAGQAAPHGDEPHSDGELRRESHSAPPTSRTLPDTILAVKRRSVAQRSHVRLDAKPGLNDRDGFRRRLLLPLSGYFRANELRNQQFMGYGTENGLKNTCLTRPLGAAGGVRETIGERQDRDVADSATQRVFHTLYAALQTVRVWYTALGTAWRTSGSRTRDSLFDGPRRRDRQAGRLRRLEL
What are the official names of this protein?
Uncharacterized protein UL150.
Protein: Y1351_LACDA
Sequence: MADYFYVHKKILPDYLEKVLEAREMLDSREAATVTEATERVGISRNTYYRYKDYVFRAKDPARGQQAVLSLLLADLPGALSAVLTCVTDHRASVLTISQAIPLASHASVLMSLDLAGLKGDINTLLADLKSLPFVKNLQLAGLE
What are the official names of this protein?
UPF0735 ACT domain-containing protein Ldb1351.
What is the protein family that this protein belongs to?
Belongs to the UPF0735 family.
Protein: H2BV1_DICDI
Sequence: MRHRGRRSTQHTHVREGIYIKKLIKQINPACRIQVKSVQILTSLIRDTTISIMNEAFHLVQLSNKRTLSARDVQTSVRLCTVGEISRHAVSEGVKRVTNFNSAKQYPPQPPPAKTATPSSPSSIPAPPISHPPIIPHSYLKTKVKQMNYNYRISNSSMHYLSAVIEYLLSEILELSSNGAVSAKRTLIQPRDIFLAIANDIELHSMYGHVIIPGGGTKPLFNSLSF
What are the official names of this protein?
Histone H2B.v1.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
Protein: GRPE_LEGPC
Sequence: MSKQNKKDWKKFKDEHKEEYKVENEILEEETDEESQHQEPALGHPSYTALEEQLTLAEQKAHENWEKSVRALAELENVRRRMEREVANAHKYGVEKLISALLPVVDSLEQALQLADKNSDPSMHEGLELTMKLFLDALQKFDVEQIDPLGQTFDPQQHEAMSMQPAPGAPPNSVITVFQKGYKLSDRVIRPARVIVSTK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VU4_ELHVK
Sequence: MQSLYNSKYAHIFKGPVAKHVTYKFHDLEVTYANIPHLDITVENITPDMIYKSAHLTCSSLFRMYGLSPETDGKLWVLLYRLFTVNEGSYDHRNTIGLELYINHLTAMYEELKVKSELLACVNFALGLGYFYMSYFVMYNHKKGNLLNYLHELCHVIHRYIDQIRLLHMRNPNNYKIEEFMRILRDVFKHYRISQFYDHVMYNHIFGLTRIVSNILCGCSSVCKEHYSIKDRDKSVRGIKTRVKPASAGQSPVLSIPVGFYVNQAISIKTRFPTTGPELFGQAENVIGILRSPVLYHVSQDDVAKIEMCLKTDFYMTEFYNNKEANNYIIPIQSPGCREQEEMMLKLFNNVVFCMYLACQVRQVILSQWKILLTLFRNQFLKIVSLMKGDSFIKICIERLADDIQHHRQSLGAVFKAFLTILPDVLKHVGFPVNDSNALRAHLLVEYLVDDKFAPEIPYDTYVRMARDYRLEILRGNRMPFPIFTLDLAETRNLIFSNEAFHAFYNVISYDDIIPNYSSF
What are the official names of this protein?
Protein U4.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae U4 family.
Protein: SHH_RAT
Sequence: MLLLLARCFLVALASSLLVCPGLACGPGRGFGKRQHPKKLTPLAYKQFIPNVAEKTLGASGRYEGKITRNSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDKLNALAISVMNQWPGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWVYYESKARIHCSVKAENSVAAKSDGCFPGSATVHLEQGGTKLVKDLSPGDRVLAADDQGRLLYSDFLTFLDRDEGAKKVFYVIETREPRERLLLTAAHLLFVAPHNDSGPTPGPSPLFASRVRPGQRVYVVAERGGDRRLLPAAVHSVTLREEAAGAYAPLTADGTILINRVLASCYAVIEEHSWAHRAFAPFRLAHALLAALAPARTDGGGGGSIPAPQSVAEARGAGPPAGIHWYSQLLYHIGTWLLDSETLHPLGMAVKSS
What is the function of this protein?
The dually lipidated sonic hedgehog protein N-product (ShhNp) is a morphogen which is essential for a variety of patterning events during development.  Induces ventral cell fate in the neural tube and somites (By similarity).  Involved in the patterning of the anterior-posterior axis of the developing limb bud (By similarity).  Essential for axon guidance (By similarity).  Binds to the patched (PTCH1) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes (By similarity).  In the absence of SHH, PTCH1 represses the constitutive signaling activity of SMO (By similarity).
What are the official names of this protein?
Sonic hedgehog protein, SHH, Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains, ShhNC.
What is the protein family that this protein belongs to?
Belongs to the hedgehog family.
What are the subcellular locations of this protein?
[Sonic hedgehog protein]: Endoplasmic reticulum membrane. Golgi apparatus membrane. Note=Co-localizes with HHAT in the ER and Golgi membrane. SUBCELLULAR LOCATION: [Sonic hedgehog protein N-product]: Cell membrane; Lipid-anchor. Note=The dual-lipidated sonic hedgehog protein N-product (ShhNp) is firmly tethered to the cell membrane where it forms multimers (By similarity). Further solubilization and release from the cell surface seem to be achieved through different mechanisms, including the interaction with DISP1 and SCUBE2, movement by lipoprotein particles, transport by cellular extensions called cytonemes or by the proteolytic removal of both terminal lipidated peptides.