PharMolix/UniProtQA huggingface dataset:
Protein: ITA2_MOUSE
Sequence: MGPGQAGGALLLRLLMLVQGILNCLAYNVGLPGAKIFSGPSSEQFGYSVQQLTNPQGNWLLVGSPWSGFPENRMGDVYKCPVDLPTATCEKLNLQNSASISNVTEIKTNMSLGLTLTRNPGTGGFLTCGPLWAHQCGNQYYATGICSDVSPDFQFLTSFSPAVQACPSLVDVVVVCDESNSIYPWEAVKNFLVKFVTGLDIGPKKTQVALIQYANEPRIIFNLNDFETKEDMVQATSETRQHGGDLTNTFRAIEFARDYAYSQTSGGRPGATKVMVVVTDGESHDGSKLKTVIQQCNDDEILRFGIAVLGYLNRNALDTKNLIKEIKAIASTPTERYFFNVADEAALLEKAGTLGEQIFSIEGTVQGGDNFQMEMAQVGFSADYAPQNDILMLGAVGAFDWSGTLVQETSHKPVIFPKQAFDQVLQDRNHSSFLGYSVAAISTEDGVHFVAGAPRANYTGQIVLYSVNKQGNVTVIQSHRGDQIGSYFGSVLCSVDVDKDTITDVLLVGAPTYMNDLKKEEGKVYLFTITKGILNQHQFLEGPEGTGNARFGSAIAALSDINMDGFNDVIVGSPVENENSGAVYIYNGHQGTIRTKYSQKILGSNGAFRRHLQFFGRSLDGYGDLNGDSITDVSIGALGQVIQLWSQSIADVAIEALFTPDKITLLNKDAKITLKLCFRAEFRPAGQNNQVAILFNMTLDADGHSSRVTSRGVFRENSERFLQKNMVVNEVQKCSEHHISIQKPSDVVNPLDLRVDISLENPGTSPALEAYSETVKVFSIPFYKECGSDGICISDLILDVQQLPAIQTQSFIVSNQNKRLTFSVILKNRGESAYNTVVLAEFSENLFFASFSMPVDGTEVTCEVGSSQKSVTCDVGYPALKSEQQVTFTINFDFNLQNLQNQAAINFQAFSESQETNKADNSVSLTIPLLYDAELHLTRSTNINFYEISSDENAPSVIKSVEDIGPKFIFSLKVTAGSAPVSMALVTIHIPQYTKEKNPLLYLTGIQTDQAGDISCTAEINPLKLPHTAPSVSFKNENFRHTKELDCRTTSCSNITCWLKDLHMKAEYFINVTTRVWNRTFAASTFQTVQLTAAAEIDTHNPQLFVIEENAVTIPLMIMKPTEKAEVPTGVIIGSIIAGILLLLAMTAGLWKLGFFKRQYKKMGQNPDEMDETTELNS
What is the function of this protein?
Integrin alpha-2/beta-1 is a collagen receptor, being responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.  It is also a receptor for laminins, collagen C-propeptides and E-cadherin.  Mice homozygous for a null mutation in the alpha-2 die very early in embryogenesis.
What are the official names of this protein?
Integrin alpha-2, CD49 antigen-like family member B, Collagen receptor, Platelet membrane glycoprotein Ia, GPIa, VLA-2 subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the integrin alpha chain family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: CJ040_HUMAN
Sequence: MKHKYNTLSWYKKERSTQLRRFIVHQPEVGLFFFLRDVVYNYITEKTTCRCPLTQERPCDTGGKFGRIWICQPEELGKMQIWICQPEELGKMQIDKNRTMVQQMWYIWYGGLDTSTNSLLPILVRGMA
What are the official names of this protein?
Putative uncharacterized protein encoded by LINC01553.
Protein: PKHO1_DANRE
Sequence: MKKSHLVKRGLQDANQPSSQPDKVGWIRRFSGKGIFREIWRNRFVMLKGDHLFIFEKEMKNNGKTHEVFDLVHYERSEELRKAKSHSKKNHSKFTLLRCQHPGNKSPNLVFLAVSPEEKESWINVLNTAITRAKNRVLDEVTIEEESLLAHPTRDRAKIPLGRRLPTRGHLMAVGSASSDGMLTLDLVNEEDAAMLDEDEWLKDHRASLDKLAPGRRRAGTDASRPPASNTEAQEKTSSLPRKSEISWSQEDHPRTPQNKKKFAQVRNRCASMDDALSRGERKPKKNIPSPTGHLQDLITQRLQRTQELLAQIQEQEPHRGRMGSYPYLRGIDSPRLRHLKGSDSPHSKGSSSPHSANSPSVRAKDSPSSKSKESPHAKSKDSPRFKSSKNALRSKSIDSPDSKESSSLHMKCIDLTHIKGSQSPLSTGSNSPHMKSTDFYQMSYSPNFRNMKGGDSPLGEALDWDSRRAAAERLLQEAISSWREAKEVLAEVKELQARQRREELSKTGMASQKLQQKSP
What is the function of this protein?
Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP).
What are the official names of this protein?
Pleckstrin homology domain-containing family O member 1-A, PH domain-containing family O member 1-A, Casein kinase 2-interacting protein 1, CK2-interacting protein 1, CKIP-1.
What are the subcellular locations of this protein?
Membrane. Nucleus. Cytoplasm.
Protein: PUS3_ORYSJ
Sequence: MLCRRRRVGAAVRWLSRLAPPAPAEADPVVVRVDGSNVARLGKPKPGPRPRQLLSLPPFPGGGDGDPLPGRKAAAPRRVTAVSWVKHYLADVPQEVVQAHFNKRLVYSECSDHEVSVETIKSQKHHLKKIKHNDVMEPGMRIHLPVSVAEGEIKKRYETIPTATLHPNKDEIEYLRRLVIHKDSAILVLNKPPKVPMKGNLPVHNSMDVLAAAALSYGNEEGPKLVHRLDRESSGLLLFGRTKESFTRLHWLFTSVNLAKTNSQVWNAACEAYMQRYWALVIGTPKEREGIISAPLSKVLLDDGKAERVILAHPSGIDGAQEAVTAYRVMGPTIHGCSWIELRPLTGRKHQLRVHCAEALGTPIVGDYKYGWFVHQRWKQNPQPDFEPFTGEPYKLRRPEGLEIQKGSVLSKVPLLHLHCREMVIPNIAKFLSSNGEWHENGAPWSKEKPNLLRFIAPMPAHMKISWNIMSSYLV
What are the official names of this protein?
RNA pseudouridine synthase 3, mitochondrial, RNA pseudouridylate synthase 3, RNA-uridine isomerase 3.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RluA family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: DER_THEAB
Sequence: MPTVLIVGKSNVGKSTLFNKLIGYKKSIVDDKEGVTRDAVSGRVSYYSKTFNIVDTGGIFENPEDDIINKSKDLTLKMLNEADLILFVIDAKNGITSEDYYLADIIRKSNNDVILVSNKSESERRVQNNLPDIYKLGFGDPIFVSAEQGKNIDTLIERIVNVLESKGLSLEENLKEESQSIIRVSFIGRPNAGKSTLFNSILNKERVLVTPIPGTTRDSVDELVTINGRKYLFVDTAGLRRKSKVDYKSLDMYSNVRSIKSIENSDVVVILIDAIEGITHQDQRIAGIAENRGKATIVAFNKIDLIKNFKYKKEEFIDQFNEKLYFINYSPLIFLSAINKKGIDNLINAIDEAYKSLHYRVQTSAVNSAIQRMMAFTPPPKGLKILYGTQVDIRPPTFLFFTNGKKVPEFYQNHIRKTIRENIYPFVGAPIFLKFKSRH
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: UBID_PSYIN
Sequence: MKFDDLRDFIGQLEERGLLKRIKQEIDPHLEMTEISDRTLRAGGPALLFENPKGFDTPVLTNLFGTTQRVALAMGQDDVAALKEVGKWLAYLKEPEPPKGIKSLWEKLPIFKQVLNMPTKKVRSPACQQVIMEGDDVDLTKLPIMTCWPGDVAPLITWGLTITKGPYKKRQNLGIYRQQLLGKNKIIMRWLSHRGGALDFREWQEVNPGKPFPVSVALGADPATILGAVTPIPDTLSEYAFAGLLRGSRTKVAKSISNDLDIPATAEIILEGYLQPGEEAPEGPYGDHTGYYNEVDDFQVMTVTHVTHRENPIYLSTYTGRPPDEPSILGVALNEIFVPILQKQFPEIVDFYLPPEGCSYRMAVVSIKKSYPGHAKRVMFGIWSFLRQFMYTKFIIVCDDDVNVRDWNDVIWAITTRMDPSRDTTLVDNTPIDYLDFASPVSGLGSKMGMDATNKWAGESDREWGTPILMDKKVKEKIDDLWQDLDILS
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PXR1_PHANO
Sequence: MGLAAPKNRSKISNDPQNTTWANNTSRFGHRILTSQGWQPGDSLGASDAAHAAHYTVASQSHIRVLLKDDNLGLGAKRGSERAENFGLAGLESILGRLNGKEAEVKKEEERREEIEKRAFVYRKYGMMNFVSGGFLVGDKIKSRDEVKTETQAKVEVKSEPESDGAKEDDRKKKRKRKDRDEAGVEGEEEPKLKRKKKSMDLRDQAKKDIAAESSKDKKGKKSKKDKKAVTSDPEPTSSGVASPASDPEPLTDKARRKAEKKARKEEKRLKKALKKAAKEAAKPMGDVEDLSSESEDESTPSASRPATGTSTPTVSAAGLTFNPRGMHSVRQKWIRSKKSATMDAQAMREIFMIKTPS
What is the function of this protein?
Involved in rRNA-processing at A0, A1 and A2 sites and regulates negatively telomerase.
What are the official names of this protein?
Protein PXR1, PinX1-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the PINX1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: NDK_METSB
Sequence: MAIERTFSIIKPDATRRNLTGAINALIEKAGLRIIAQKRVQITRPQAETFYAVHKERPFFGALVDTMISGPVVVQVLEGENAIKAYRDVLGATDPAKAAPGTIRKEFALSVGENSGHGSDASETAAIEIAQWFSGNEIVG
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SODF_NICPL
Sequence: KFELQPPPYPMDALEPHMSSRTFEFHWGKHHRAYVDNLNKQIDGTELDGKTLEDIILVTYNKGAPLPAFNNAAQAWNHQFFWESMKPNGGGEPSGELLELINRDFGSYDAFVKEFKAAAATQFGSGWAWLAYKPEEKKLALVKTPNAENPLVLGYTPLLTIDVWEHAYYLDFQNRRPDYISIFMEKLVSWEAVSSRLKAATA
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Fe], chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RNH2_LIGS1
Sequence: MEKLTIAQIKKMLTEEISSEQLAELKLDERKGVQLAIKSYEKRLKKIENEKLEFQNRLKIERDLWDKGIEYIAGVDEVGRGPLAGPVVTAAVILPHDFDVFEVNDSKQLSEKKREELYKKILEKAVAVSVGLSDNNLIDEVNIYEATRLAMKQAIESLNITPQKIIVDAMTIDTKIPQLRLIKGDAKSASVAAASIVAKVTRDHLMQFYARIYPGYGFEKNDGYGTKQHLEGLENKGVTPIHRQSFEPVKKILLK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLA2_RAT
Sequence: MRYVASYLLAALGGNSNPSAKDIKKILDSVGIEADDERLNKVISELNGKNIEDVIAQGVGKLASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEKKDEKKEESEESDDDMGFGLFD
What is the function of this protein?
Plays an important role in the elongation step of protein synthesis.
What are the official names of this protein?
60S acidic ribosomal protein P2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein P1/P2 family.
Protein: CYSI_ECOLI
Sequence: MSEKHPGPLVVEGKLTDAERMKHESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTKQWQAIDKFAGENTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKAEVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDDNWHLTLFIENGRILDYPARPLKTGLLEIAKIHKGDFRITANQNLIIAGVPESEKAKIEKIAKESGLMNAVTPQRENSMACVSFPTCPLAMAEAERFLPSFIDNIDNLMAKHGVSDEHIVMRVTGCPNGCGRAMLAEVGLVGKAPGRYNLHLGGNRIGTRIPRMYKENITEPEILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDLWD
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: FUSE_BURCE
Sequence: MQIDPSHYQIAVEQAQAVAAAARSCRCRRRGRRADLDALVVSKENRENAAHSASSADAQYQQAIAALDARSSTLERSRVVAPVDGYITNLQTFKGNYAVAGQAKLAIVDSHSFWVYGYFEETKLPRVKIGAPAEMRLMSGGVMKGHVESISRGIYDRDNPQSRDLVRT
What is the function of this protein?
Involved in the resistance (detoxification) of the fungal toxin fusaric acid.
What are the official names of this protein?
Fusaric acid resistance protein FusE.
Protein: OTC_GLOVI
Sequence: MSASLGATRFRPDLLSLDDLDEAQLHALLTLAHQLKRGERVANLHGKVLGLVFLKASTRTRVSFTVAMYQLGGQVIDLSPSNTQVGRGEPVRDTARVLGRYVDGLAIRTFAQTELEEYAHYAGIPVINALTDHEHPCQVVADLLTIRENFGRLAGLKLAYVGDGNNVAHSLLLGCAKVGMSIAVATPEGFTPDPAVSARASEIAGRTGAEVQILRDPFEAARGAHILYTDVWTSMGQEAETQHRLQLFEQYQINAALLNCAAAEAIVLHCLPAHRGEEITDEVMEGPRSRIWDEAENRLHAQKAVLAALMGGR
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECO_GLAP5
Sequence: MIEQWQRGFVLHRREYSESSLLVDFFTENHGRITLLAKGVRRPRSPLKSVLQPFTPLLLKWTGKGDLKTLTKAEPASLTLPMQTLALYSGFYVNEVLARVLENHTAYPELFQHYLHCMTKLASQPNEIEPILRTFEFQTLKALGYGVDFCHCAATGKPVDPKMSYQFRENEGFIASLLQNNYTFIGKDLLAFAEMDFSEKETLQSAKRFTRIALKPYLGSAPLKSRELFQSVLPNRLKG
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: CH60_ECO27
Sequence: MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIITEGLKAVAAGMNPMDLKRGIDKAVTAAVEELKALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDRGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPKNDAADLGAAGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_ACTPJ
Sequence: MASQFELSVVSAEKEIFNGNVVSVRVTGIDGELGVYAGHTPLLTSIKPGMVKYTLEDGKEEFIYVSGGFLEVQPTIVTVLADVAIRGEELDQQRILAAKRKAEDTLSKSNNAELSAKLSREIAKLRVYEIVNSKLANRR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL19_XENLA
Sequence: MSMLRLQKRLASSVLRCGKKKVWLDPNETNEIANANSRQQIRKLVKDGLIIRKPVTVHSRARCRKNTLARRKGRHMGIGKRKGTANARMPEKLSWMRRMRILRRLLRRYRESKKIDRHMYHSLYLKVKGNVFKNKRILMEHIHKLKADKARKKLLADQAEARRSKTKEARKRREERLQAKKEEIIKSLSKEEESGKK
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL19 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSGA_NEIM0
Sequence: MPSEHPFSDGISTLNPKETMNDTAQITASYGRRYIVRTPDGTTYEASTRKKRVDFACGDRVRISPVNAEQVVIEDFLPRQSLLYRQDAWKTKLIAANVTQLLIVTAAVPSPSVRLLQRALLAAEAAGIRAVIVLNKADLPETALWREKLKFYETLGYPVIETRALENAGSLRPALQGHSNILLGQSGMGKSTLTNALLGSQTARTGDISAALDSGKHTTTHARLYDLNGETQLIDSPGLQEFGLHHLQAADLPRYFPDFRHLVGQCRFHNCTHRAEPGCAFKAAAETRAASPERLAFLQGITDELPG
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_STRP7
Sequence: MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLVAENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: YR900_MIMIV
Sequence: MYKMKRNTLFVRQSCVSSSRIGTQLPLNKSKIYTSSSINITNYKQDQKLYTRHYYTNGKIFENKKVDQYLKVTEEMVFSFMNGFTDGCICGTIIILCLINT
What are the official names of this protein?
Uncharacterized protein R900.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SECG_BORBU
Sequence: MDLVRFFIFIIFVIVSIFIILLVLIQDEQGDGIGGVFGGGSSSIFGAKSSSVAVKITGFFIALFFIFVVLLSFLNTRRADDSFLNDIKTENKNSSTFWDDENSESDANINEIKENNLKEK
What is the function of this protein?
Involved in protein export.  Participates in an early event of protein translocation (By similarity).
What are the official names of this protein?
Probable protein-export membrane protein SecG.
What is the protein family that this protein belongs to?
Belongs to the SecG family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BIOB_GEOSL
Sequence: MINYPESLANRIIKGSTLDKDEANELLLLEGTDANALFLAASRVRDHFLGTGVDLCSIINAKSGRCPENCAFCAQSAHHATNAPVYPLVDEEQITACAREAAGAGSHCFGIVTSGSAISRGEELDRICRALRRIRRETAIEPSCSLGVIDYETALALREAGAVTYHHNLETARSFFPNVCTTHDYEEDVETVRVAKRAGLKVCCGGIFGLGETPEQRVEMALTLRELDVDSIPLNFLNPIEGTPLAGADRITPLECLKTIAVYRLILPDRKIAVCGGRERNLRDLQSWMFFAGASGTMIGNYLTTTGRPPEQDWQMLADLGLTVRQCNG
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: STC_ONCKE
Sequence: FSPNSPSDVARCLNGALDVGCGTFACLENSTCDTDGMHDICQLFFHTAATFNTQGKTFVKESLRCIANGVTSKVFQTIRRCGVFQRMISEVQEECYSRLDICGVARSNPEAIGEVVQVPAHFPNRYYSTLLQSLLACDEETVAVVRAGLVARLGPDMETPFQLLQNKHCSQGSNQGPNS
What is the function of this protein?
Its primary function is the prevention of hypercalcemia.  Upon release into the circulation, it lowers calcium transport by the gills, thereby reducing its rate of influx from the environment into the extracellular compartment.  STC also stimulates phosphate reabsorption by renal proximal tubules.  The consequence of this action is increased levels of plasma phosphate, which combines with excess calcium and promotes its disposal into bone and scales.
What are the official names of this protein?
Stanniocalcin, STC, Corpuscles of Stannius protein, CS, Hypocalcin, Teleocalcin.
What is the protein family that this protein belongs to?
Belongs to the stanniocalcin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MOAA_ALKMQ
Sequence: MKDTFQRSINYMRISITDLCNLRCQYCMPEKGIYKKTHQDILTLEEIEQIVRIGAENGINKVRITGGEPLVRKGVIGLIKNISNIPGIQDIALTTNGLLIKKYGEALKDAGLKRINISIDSLRPDRYKEITRGGDLSQVLEGIQEALRLGMTPVKLNVVVIGGYNEDEIEDFANLTVDDPIDVRFIELMPIGEASGWAKDRFLSNEEVKSKIEGLVPIITDATSPARLYRLPGAKGRVGFINPISSHFCESCNRIRVTSDGKLKPCLHSNHEIDLLRVARENPEQIGAVLSNGIQLKPEKHYLYTNKHEMSARSMSEIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: RRAA_ACTP2
Sequence: MRIDTSALCDIYSDQVDVVEPIFSSFGGASSFYGKITTVKCFESNGLIASVLEEEGQGRVLLIDGGGAVRRALIDAELAQLALDNGWEGIIVYGAVRQLDVLETLDIGIHALAPIPVGADDNEIGEVDTPVNFGGVTFFPEDYVYADLTGIILSPELLDLAELEE
What is the function of this protein?
Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity.  Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.  Modulates RNA-binding and helicase activities of the degradosome.
What are the official names of this protein?
Regulator of ribonuclease activity A.
What is the protein family that this protein belongs to?
Belongs to the RraA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE1_RUBXD
Sequence: MAPSVRARFAPSPTGDLHLGGARTALFNYLFARHHGGRLLLRIEDTDRQRSRREHEERILEDLGWLGLRFDEGPYRQSERGEVYAGYAGRLLEGGLAYEAEDASGRRAVYFRPPERGGAFRDALRGEVRFGGVRDFVILKSDGMPAYNFAAVVDDIEMEITHVIRGEEHLPNTGRQALLYRALGVPEPEFLHLGLILGPDGRKLSKRHGAQSVRGYREEGYLPEALLNYLALLGWTHPEGREEFSGLEELVAEWDPSRLGSSPARFDPQRLLYFNARHLRRLPARRLARLVEPFLEEPLPPGREEVAVEAVREELRLLSDAPRLLGRLLGPVDPGAAAGRPPGGAGEALAAASRLLESRRPEGLEEARELLAALRRWAKERGIKAREALHPLRVALTGEDRGPRLEYIIVLLGPEEAQKRIERAREARLRA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 1, Glutamyl-tRNA synthetase 1, GluRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DOC2A_MOUSE
Sequence: MRGRRGDRMTINIQEHMAINVCPGPIRPIRQISDYFPRRGPGPEGGGGGGGTGCGEAPAHLAPLALAPPAALLGATTPDDGAEVDSYDSDDTTALGTLEFDLLYDQASCMLHCRILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEELTYSGITDDDITHKVLRISVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHFNICLERQVPLPSPSSMSAALRGISCYLKELEQAEQGPGLLEERGRILLSLSYSSRRHGLLVGIVRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEAQKHWNDCLHQPDTALERWHTLTSELPPAAGAYPLA
What is the function of this protein?
Calcium sensor which most probably regulates fusion of vesicles with membranes.  Binds calcium and phospholipids.  May be involved in calcium dependent neurotransmitter release through the interaction with UNC13A.  May be involved in calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells.  Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells.
What are the official names of this protein?
Double C2-like domain-containing protein alpha, Doc2-alpha.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein. Synapse, synaptosome. Lysosome.
Protein: RL10_ALCBS
Sequence: MPLNLEDKRAIVASVNAVAAEALSAVVADYRGLTVSQMTELRSKARETGVYLKVVRNTLAKFAVKDTEFECLNDALVGPTVLAFSKDDPGAAARLIKDFAKDHDALEVKALAVGGVTYGAQDIDVLAKLPTRDEAISQLMSVMQAPVAKFVRTLNEVPGKFVRTVAAVKDQKQSAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: YFBV_SALNS
Sequence: MSTPDNRSVNFFSLFRRGQHYAKTWPMEKRLAPVFVENRVIRMTRYAIRFMPPVAVFTLCWQIALGGQLGPAVATALFALSLPMQGLWWLGKRSVTPLPPSILNWFYEVRGKLQEAGQALAPVEGKPDYQALADTLKRAFKQLDKTFLDDL
What are the official names of this protein?
UPF0208 membrane protein YfbV.
What is the protein family that this protein belongs to?
Belongs to the UPF0208 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EFTU_WIGBR
Sequence: MSKEKFQRIKPHINVGTIGHVDHGKTTLTAAITNVLAKKYGGIPKAFDQIDNAPEEKARGITINTSHVEYDTKIRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIVVFMNKCDMVDDEELLELVEIEIRELLSQYDFPGDEIPIIRGSALKALEKDPIWIQKIIDLSEHLDNYIPEPKRIIDQPFLLPIEDVFSISGRGTVVTGRIERGTVKVGEEIEIIGIKNTVKTTCTGVEMFRKLLDEGRAGENVGILLRGTKREDVERGQVLAKPGSIKPHTQFESEVYVLKKEEGGRHTPFFNGYKPQFYFRTTDVTGSVELQKGTEMVMPGDNVKMLVKLISPIAMDDGLRFAIREGGKTVGAGIVSKIIV
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.