PharMolix/UniProtQA huggingface dataset:
Protein: RUTD_ECOBW
Sequence: MKLSLSPPPYADAPVVVLISGLGGSGSYWLPQLAVLEQEYQVVCYDQRGTGNNPDTLAEDYSIAQMAAELHQALVAAGIEHYAVVGHALGALVGMQLALDYPASVTVLISVNGWLRINAHTRRCFQVRERLLYSGGAQAWVEAQPLFLYPADWMAARAPRLEAEDALALAHFQGKNNLLRRLNALKRADFSHHADRIRCPVQIICASDDLLVPTACSSELHAALPDSQKMVMPYGGHACNVTDPETFNALLLNGLASLLHHREAAL
What is the function of this protein?
Involved in pyrimidine catabolism.  May facilitate the hydrolysis of carbamate, a reaction that can also occur spontaneously.
What are the official names of this protein?
Putative carbamate hydrolase RutD, Aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Hydrolase RutD family.
Protein: BIOB_PHEZH
Sequence: MNAHVRPVDPANVDPAQPRHDWTLEEVEALFELPFTELVFRAAEVHRRWFDPTELQLSQLLSVKTGGCPEDCGYCAQSQKFKTGLAASKLMEAETVIAAAAEAKAGGAQRFCMGAAWRDLKDRDLPKVAAMISGVKALGLETCATLGMLTADQAKALKAAGLDYYNHNLDTGPDYYDKVVTTRTYQDRLDTLAAVRDAGMATCCGGIVGMGETRRDRAGLLHQLATLPAHPDSLPINDLMPIPGTPLGDSKAVDPLEFVRMIAVARIVCPKSMVRIAAGREHMTKELQALCFLAGANSIFVGARLLTTDNPEKTADEALLADLKMKPMAMA
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: YAIF_LACLA
Sequence: MKFIFSKSIIIATAFFLFILSQLPAVFLNFLNSNGDTYGIAHKNTPPFIILTLVVVTICIFIGIKCGFYQNYRKSLEWKNILLIFSLLIITFFIQKFVVQFITSHNLYNVSHQITNQMKVENILSSLLFPGQFVAVSILAPILEESIYRACFYKLFGYYRWTFFLSCFFFSYVHSGFSWDILGYLPLSIALTYVYHRRQVLTDSILLHALFNTLLFVF
What are the official names of this protein?
UPF0177 protein YaiF.
What is the protein family that this protein belongs to?
Belongs to the UPF0177 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL20_VESOH
Sequence: MARVSRGVQAHAKHKKILKKAKGYYGARSKVYRIAKQAIIKAGQYAYRDRRQRRRQFRRLWIVRINAEARNNGLSYSRMINGMSKAGIEIDRKVLSDIAIFDKVAFAKIVDQVKQALSV
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: GSA_POLSJ
Sequence: MEPQNIKPHTPELSRNTALFERAKKLIPGGVNSPVRAFKAVGGTPRFVQRAQGAYFWDADDQRYIDYIGSWGPMILGHGHPAVLASVQKALLDGFSYGAPTEREVELAEELVRLVPSLEMVRLVSSGTEAAMSAIRLARGATGRSKIIKFEGCYHGHADALLVKAGSGLATFGNPTSAGVPPEVVQHTLVLEYNHLAQLEEAFALHGSAIACLMIEPIAGNMNFVRASIPFMQRCRELCTQYGALLVFDEVMTGFRVALGGAQSVYAKSIPGFKPDMTVLGKVIGGGMPLAAFGGTRAVMEQLAPLGPVYQAGTLSGNPVATACGLATLREIQKPGFYEALGERTRGLVAGLTQAANKAGVPFCGDSEGGMFGFFLLGQLPQNYATVMTTDGPAFNRFFHAMLASGVYYAPALYEAGFVSSAHSAADIEATVDAAAKFFAGA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_THESQ
Sequence: MKVILLRDVPKIGKKGEIKEVSDGYARNYLIPRGFAKEYTEGLERAIKHEKEIEKRKKEREREESEKILKELKKRTHVVKVKAGEGGKIFGAVTAATLAEEISKTTGLKLDKRWFKLDKPIKELGEYSLEVSLPGGVKDTIKIRVEREE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: RL9_PHEZH
Sequence: MKVILLERLEGWGGLGDVVDVKDGYARNFLLPRQKALRANGANLKVFEAQRAEIEARNAKAKEAAGKAGEKLDGTQYVLIRQAGESGQLYGSVSGRDVADAVNAEGGKVERSMVVLDKPIKTLGMHEVKIRLHSEVAVTVTLNIARSQDEADRQARGENVIASQFEDERMAAEQAAADLLEGGAGQQASEYTEAQA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: NUOD_MYCBP
Sequence: MTAIADSAGGAGETVLVAGGQDWQQVVDAARSADPGERIVVNMGPQHPSTHGVLRLILEIEGETVVEARCGIGYLHTGIEKNLEYRYWTQGVTFVTRMDYLSPFFNETAYCLGVEKLLGITDEIPERVNVIRVLMMELNRISSHLVALATGGMELGAMTPMFVGFRAREIVLTLFEKITGLRMNSAYIRPGGVAQDLPPNAATEIAEALKQLRQPLREMGELLNENAIWKARTQGVGYLDLTGCMALGITGPILRSTGLPHDLRKSEPYCGYQHYEFDVITDDSCDAYGRYMIRVKEMWESMKIVEQCLDKLRPGPTMISDRKLAWPADLQVGPDGLGNSPKHIAKIMGSSMEALIHHFKLVTEGIRVPAGQVYVAVESPRGELGVHMVSDGGTRPYRVHYRDPSFTNLQSVAAMCEGGMVADLIAAVASIDPVMGGVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RUTR_SHIFL
Sequence: MTQGAVKTTGKRSRAVSAKKKAILSAALDTFSQFGFHGTRLEQIAELAGVSKTNLLYYFPSKEALYIAVLRQILDIWLAPLKAFREDFAPLAAIKEYIRLKLEVSRDYPQASRLFCMEMLAGAPLLMDELTGDLKALIDEKSALIAGWVKSGKLAPIDPQHLIFMIWASTQHYADFAPQVEAVTGATLRDEVFFNQTVENVQRIIIEGIRPR
What is the function of this protein?
Master transcription regulator which represses the degradation of pyrimidines (rutABCDEFG) and purines (gcl operon) for maintenance of metabolic balance between pyrimidines and purines.  It also regulates the synthesis of pyrimidine nucleotides and arginine from glutamine (carAB) and the supply of glutamate (gadABWX) (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator RutR, Rut operon repressor.
Protein: FTSHL_OLTVI
Sequence: MTQLSSSQPIGETFTIWKFTFFKFYFGILDHREQTKNLFLNYSTKYISFEFLCCCFPFFIGLTQLVLLRYQNQFTSEVLQKTIPGLGSSYQPISWETFSYLNYKSYLSEGEAPHPFNKEGSLSKNSASSERREPNLMGLSPLYNTPQIDVYSDSIIITPPQKLDFSSAANSQSLLGWGDQQNPLIVGEIKSQKPTGYLSEVVEKKWILPSRNAVIFYKTNSSHGKDIQKLKIKKPLGSLRLEIFGRKSPYGLDLFPKKLNPIYAKLNPSTLPDGGKVSVGLFSESSARTGDSTVFKSTLNPAGVVKKEESKSLQGFLKLSKKNFDPLNYQQRTQVQQAVFDSLLYNQGLLVNNASRPIKLKPKANSFLDTTFDLIRSKKQKLSAKKTGGFAIPENSNKKVECSNSKLQNYNLLERYTLWKNYKAQTNERNTRAFNEQQSFLFDSNNGSVKKESNQYSTQAPQHGPSPNTPKGVLRDGSVGGGWKSLTKVHSLLTQWNYVQKRNNLTSRLMSGYNYPDVTNDGVKALNSSLTSFLSSGSRSPFGDTLRRPATNQSQRLSRMLPLKIHLPGNSTSAITYPVPATGWTTSPQHSFRSVGGNAFTDKLSRANDSQPAPQHLSPNTPKGVLRDGSVGGENQKEQEKQQNSGSLYQTTRGRSFGNPFSTQLVFLQRVLETDKNESQTDSEASSAMLRPQHFGSIGERSGLSQTTLNGGNQFKQTEGTLLNQIRKDSFTLSYQNAKKPTNWSRKTKAYVLLDCETNDLTPEQTLSTKPAFEGEALRPSDLKLWLKTYLSSDNPALKHKSTFFSTDTTKTPMLTELKATPDGRSTPKGSPEGARDLAISNQPSNTQKTKEKNSSHWSTEGRSTPSSLQVTKSLKVIETPTQTDANGQQIDLNRETRRWSIPGYQTWQIPLIDKHSSLFLLERLEPKLYKKITEFLTNDSKLSFNASQKVGPTGLPAEKEKVSERVLQESFTRNVLPLTEVRYPTNSVFMGNRNQSQNVLATENEYPASFFDLKSLSFFLENKTKKVNQSVVAEGHSVGRLVYNKKINFRSSPKINFHYLPVVEGPVYGATQNTLQVAGTYSKTTSVYKHLTTKSNQSSSTINQSRSEVPTNRVETWEPLTPFSWLIVTQLSFGLISLKVLQNLYQDYGKELISYVLDLLSIFGDSVEASLDESLKEEFQAQQDGSGARLIRKVDKRFQNLAGIQRILPECSEIVWFLRNYSFMKSSGLVYLSPVDRENRCVKDALHWIQDFPEHFSSTSLHIEEEGYPVDVISKNFAKGNKIVSTLQEGGTTKSNKIQFGHSKRYSLSLVSQNLTALALAPSNWLTFEKMIPKGILLVGPPGTGKTLLVQAIAGEANVPVLVQSLSLISQPGESDSGAEKLTDLFKRARELSPCIVFIDEIDTLGIKRQNLIQNPMGTDNLLNCLYPKNSGQQLSMTDGSKSSTVRTTTRLGKECPFPPHTTRSFGLDTNKDEMETRSSESTKASHESSNEMEVEKNQLSALIRLLVEMDGLNPLNGVIVFGATNRPEVLDPALIRPGRFDQILPIELPGKQKRVEILKLYAKKLGTAKSISWEYFANRTVGLSAADLAAIMNQSTILAVFNDQRHTLKTLEYGLNIIYKPKTGPILTKKVQGELNSSLADKSSNWTVDKKASTTSKSSLTSTPQHFHGSVGGEYPPKQVVVGTPGTTLLKQQLELEKNVLFKKGLEPKSQKLEIVTPIQQQSLVSEKLDLLKKKTYKKNISQLKLKTLNKLEKLSVQSLNTKTPQHFQGLMGGVSQREGNFTESLFSEKVTYTLSQLVQTWPKVLTSSKLKQKTPQYNEVLSSESLNKKIWVSSDTTHPYSVQKQFLTYVSVKKGFGSTLDVSMSLPELTVEKWLSSDSTYATDPFTLNRFGYYQSGKVLTQCLVEKIDSKTLEVSETSQSLKTDVSKSGLLNNKQKTSPSGLLFDSACNTLDSQTQQLKTPKLTHFTRLESYFDTAEATPVVLNLFPRFKNVRYQDESLRGKTEQKGNRSNPLSLASFEKQLISLLAGKASEILFFATRSVNVTKKGNSLHRGETGSQNSNFSASNWDSNLGVDLKFANKMANAMVNQWYFYSKKVLTRKTNQLALNHNTQEFNQKETIKFFQELTNQVENEMSYSVKAYKTGYFRNFQASSGKPWWQVKVAQQVGNLESAYTDWYRIYLPDTEESERNQEWTPPDQFFQNVERLARLNNKLENFTLDSEITWNDLGKMDRDFLYQSLLLNSFNQAFQVLDISRPLLDYFTDYLIRYEIMRQDTINKCLLNYEKFTDS
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH homolog.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: RS3A_BABBO
Sequence: MAVGKNKRVSKGKKGGKKKIVDPFLKKEWYTLKAPVMFHVRNFGQTLVSKTQGTKLATDGLRGRIYEVSLADLNADEDQSYRKIKLCCEDIQGRNCLTNFHGTSVTRDKLCSLIRKNYSLIEAFTDVKTTDGYTLRMFCIGYTKRRPGQLKSTCYIRSSRTRVVRRKMIEVMQREASTTSMREVVKKIIPESIGKEIEKACKSVFPLQNVLIRKIKVLKKPKFDLTKLMEVHTDISEETGHATKVEESEEAANLLTKELDAQEA
What are the official names of this protein?
40S ribosomal protein S3a.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2667_VIBC3
Sequence: MDHRLLEIVACPVCKGKLTYDKDRQELICKLDRLAYPIKEGIPVLLEPEARSMSMDEGR
What are the official names of this protein?
UPF0434 protein VC0395_A1467/VC395_1991.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: HEM1_WIGBR
Sequence: MKLLVFGISYKTAPISLRERVIFSPENINIALNNLLKKSDILGGVILSTCNRTEVYLSIKNFYKAKKIIILWLYKFFNDLKIKEIKNNFYSYIDNYAVSHLMRVTSGLDSMILGEHQILSQVKSAFFRSLKNKNISIDLQKLFESAFSVAKKIRSETKIGSYSISIPYIICVLLKKIFISFTEIKVMLIGSGTINELIAKQLFKYKIKDLFISNRTIDHAKNLAIKVNGCVVEFNEIFKNLNKMQVIITSTYSRKLIITYKIIKSIIEKNKNKKIIFIDISIPRNIDKKIKKITGVHLYTLEDLKDLITNNLEKRKNAATLAENIIKKESIKFMSHIKGYYSSEIIKKYRFQINKLKKIYEKKALLELKLGNNPENIIKKLTYKLTNRLVHKPTKLLYNTSCSKNNKDLYDLYNKLKIDL
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: TOM70_RAT
Sequence: MAASKPVEAAMAAAAAPASGNGVGSSGGTAAPGSGAGTLPRWHVALAIGAPLLLGAGAMYLWSRRRRRREAGGRGDASGLKRNSERKTPEGRASPALGSGPDGSGDSLEMSSLDRAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNADLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILEGFQNEQSMLLADKVLKLLGKENAKEKYKNREPLMPSPQFIKSYFSSFTDDIISQPMLKGEKSDEDKDKEGEALEVKENSGYLKAKQYMEEENYDKIISECSKEIDAQGKYMAEALLLRATFYLLIGSANAAKPDLDKVISLKEANVKLRANALIKRGTMCMQQQQPMLSTQDFNMAAEIDPMNSDVYHHRGQLKILLDLVEEAVADFDACIRLRPKFALAQAQKCFALYRQAYTANNSSQVQAAMKGFEEVIKKFPRCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLDKGLELISKAIEIDNKCDFAYETMGTIEVQRGNMEKAIDMFNKAINLAKSEMEMAHLYSLCDAAHAQTEVAKKYGLKPPTL
What is the function of this protein?
Acts as receptor of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex).  Recognizes and mediates the translocation of mitochondrial preproteins from the cytosol into the mitochondria in a chaperone dependent manner (PubMed:11956321, PubMed:19401463).  Mediates TBK1 and IRF3 activation induced by MAVS in response to Sendai virus infection and promotes host antiviral responses during virus infection (By similarity).
What are the official names of this protein?
Mitochondrial import receptor subunit TOM70, Mitochondrial precursor proteins import receptor, Translocase of outer membrane 70 kDa subunit, Translocase of outer mitochondrial membrane protein 70.
What is the protein family that this protein belongs to?
Belongs to the Tom70 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: MYB75_ARATH
Sequence: MEGSSKGLRKGAWTTEEDSLLRQCINKYGEGKWHQVPVRAGLNRCRKSCRLRWLNYLKPSIKRGKLSSDEVDLLLRLHRLLGNRWSLIAGRLPGRTANDVKNYWNTHLSKKHEPCCKIKMKKRDITPIPTTPALKNNVYKPRPRSFTVNNDCNHLNAPPKVDVNPPCLGLNINNVCDNSIIYNKDKKKDQLVNNLIDGDNMWLEKFLEESQEVDILVPEATTTEKGDTLAFDVDQLWSLFDGETVKFD
What is the function of this protein?
Transcription activator, when associated with BHLH12/MYC1, EGL3, or GL3.  Promotes the synthesis of phenylpropanoid-derived compounds such as anthocyanins and proanthocyanidin, probably together with GL3 and BHLH2.  Regulates the expression of CHS, DFRA, LDOX, and BAN.
What are the official names of this protein?
Transcription factor MYB75, Myb-related protein 75, AtMYB75, Production of anthocyanin pigment 1 protein, Suc-induced anthocyanin accumulation locus 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: RETNB_HUMAN
Sequence: MGPSSCLLLILIPLLQLINPGSTQCSLDSVMDKKIKDVLNSLEYSPSPISKKLSCASVKSQGRPSSCPAGMAVTGCACGYGCGSWDVQLETTCHCQCSVVDWTTARCCHLT
What is the function of this protein?
Probable hormone.
What are the official names of this protein?
Resistin-like beta, Colon and small intestine-specific cysteine-rich protein, Colon carcinoma-related gene protein, Cysteine-rich secreted protein A12-alpha-like 1, Cysteine-rich secreted protein FIZZ2, RELMbeta.
What is the protein family that this protein belongs to?
Belongs to the resistin/FIZZ family.
What are the subcellular locations of this protein?
Secreted.
Protein: UL138_HCMVM
Sequence: MDDLPLNVGLPIIGVMLVLIVAILCYLAYHWHDTFKLVRMFLSYRWLIRCCELYGEYERRFADLSSLGLGAVRRESDRRYRFSERPDEILVRWEEVSSQCSYASSRITDRRAGSSSSSSVHVANQRNSVPPPDMAVTAPLTDVDLLKPVTGSATQFTTVAMVHYHQEYT
What is the function of this protein?
Plays a role in the maintenance of a latent infection in low-passage strains.  Additionally, sensitizes infected cells to tumor necrosis factor alpha (TNF-alpha) signaling.  Increases host TNFR1 stability and cell surface expression thus enhancing its signaling responses, leading to TNFR1 hyper-responsiveness.  By up-regulating TNFR1 surface availability, UL138 may also promote HCMV reactivation.
What are the official names of this protein?
Protein UL138.
What are the subcellular locations of this protein?
Host Golgi apparatus membrane.
Protein: FCN1_PIG
Sequence: MELSRVAVALGPTGQLLLFLSFQTLAAQAADTCPEVKVVGLEGSDKLSILRGCPGLPGAAGPKGEAGANGPKGERGSPGVVGKAGPAGPKGDRGEKGARGEKGEPGQLQSCATGPRTCKELLTRGHFLSGWHTIYLPDCQPLTVLCDMDTDGGGWTVFQRRSDGSVDFYRDWAAYKRGFGSQLGEFWLGNDHIHALTAQGTSELRVDLVDFEGNHQFAKYRSFQVAGEAEKYKLVLGGFLEGNAGDSLSSHRDQFFSTKDQDNDNHSGNCAEQYHGAWWYNACHSSNLNGRYLRGLHTSYANGVNWRSGRGYNYSYQVSEMKVRLT
What is the function of this protein?
Extracellular lectin functioning as a pattern-recognition receptor in innate immunity.  Binds the sugar moieties of pathogen-associated molecular patterns (PAMPs) displayed on microbes and activates the lectin pathway of the complement system.  May also activate monocytes through a G protein-coupled receptor, FFAR2, inducing the secretion of interleukin-8/IL-8.  Binds preferentially to 9-O-acetylated 2-6-linked sialic acid derivatives and to various glycans containing sialic acid engaged in a 2-3 linkage (By similarity).
What are the official names of this protein?
Ficolin-1, Ficolin-A, Ficolin-alpha.
What is the protein family that this protein belongs to?
Belongs to the ficolin lectin family.
What are the subcellular locations of this protein?
Secreted. Cell membrane; Peripheral membrane protein; Extracellular side. Note=Found on the monocyte and granulocyte surface.
Protein: KLH29_HUMAN
Sequence: MSRHHSRFERDYRVGWDRREWSVNGTHGTTSICSVTSGAGGGTASSLSVRPGLLPLPVVPSRLPTPATAPAPCTTGSSEAITSLVASSASAVTTKAPGISKGDSQSQGLATSIRWGQTPINQSTPWDTDEPPSKQMRESDNPGTGPWVTTVAAGNQPTLIAHSYGVAQPPTFSPAVNVQAPVIGVTPSLPPHVGPQLPLMPGHYSLPQPPSQPLSSVVVNMPAQALYASPQPLAVSTLPGVGQVARPGPTAVGNGHMAGPLLPPPPPAQPSATLPSGAPATNGPPTTDSAHGLQMLRTIGVGKYEFTDPGHPREMLKELNQQRRAKAFTDLKIVVEGREFEVHQNVLASCSLYFKDLIQRSVQDSGQGGREKLELVLSNLQADVLELLLEFVYTGSLVIDSANAKTLLEAASKFQFHTFCKVCVSFLEKQLTASNCLGVLAMAEAMQCSELYHMAKAFALQIFPEVAAQEEILSISKDDFIAYVSNDSLNTKAEELVYETVIKWIKKDPATRTQYAAELLAVVRLPFIHPSYLLNVVDNEELIKSSEACRDLVNEAKRYHMLPHARQEMQTPRTRPRLSAGVAEVIVLVGGRQMVGMTQRSLVAVTCWNPQNNKWYPLASLPFYDREFFSVVSAGDNIYLSGGMESGVTLADVWCYMSLLDNWNLVSRMTVPRCRHNSLVYDGKIYTLGGLGVAGNVDHVERYDTITNQWEAVAPLPKAVHSAAATVCGGKIYVFGGVNEAGRAAGVLQSYVPQTNTWSFIESPMIDNKYAPAVTLNGFVFILGGAYARATTIYDPEKGNIKAGPNMNHSRQFCSAVVLDGKIYATGGIVSSEGPALGNMEAYEPTTNTWTLLPHMPCPVFRHGCVVIKKYIQSG
What are the official names of this protein?
Kelch-like protein 29, Kelch repeat and BTB domain-containing protein 9.
Protein: RUVB_VIBVY
Sequence: MIEADRLIAPENPAFRDEDVIDRAIRPKKLADYQGQDHVRDQMEIFIKAAQLRNEALDHLLIFGPPGLGKTTLANIVANEMGVNIRTTSGPVLEKAGDLAALLTNLEENDVLFIDEIHRLSPMVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGATTRAGSLTSPLRDRFGITQRLEYYKIPDLQNIVQRSADCLGLSMEAEGALEVARRARGTPRIANRLLRRVRDFAEVKGNGHICADTADKALNMLDVDSKGFDYMDRKLLLAIMEKFGGGPVGLDNMAAAIGEEKDTIEDVLEPYLIQQGYLQRTPRGRIATDRAYLHFGIEK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: MATK_KUNER
Sequence: MEEFQGYLDXNRSRQHYLLYPLLFREYIYALAHDHGLNRSILFENAGYDNKXSSIIVKRLITRMYQQNSLIFSAKDSIQNQFFGHNKNLYSQILSEGFAVIVEIPFSLRFLFSLERKEIAKSHNLRSIHSIFPFLZDXFTHLDYVSDVLIPYHIHLEILVQTLRYWVKDASSLHLLRFFLHDYWNSFITPKKHITFFLKGNPRLFLFLYNSHICEYEYIFLFLRNQSSHLRSTSSGIFFERIHFYVKIEHFHFVKVFFDNNFQCILWFLKDPFMHYVRYQGKFFMASKDTPLLMNKWKCYLVNLWQYHFSVWFQPGRIDINQLCKYSLDFLGYRSSVRLNSSVVRSQMLENLFLINNAMKKFETIVPIIPLIGSLYKSNFCNTFGHPISKPSRTDSSDSDIIDRFLRICRNLSHYHSGSSKKKSLYRVKYILRLSCVKTLARKHKRTVRTFVKRLGSEFFEEFLTEEEVVFSLIFPRTYSTSRRLYRGQIWYLDITSINDLVNYE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RLMH_ACIBC
Sequence: MKIRILTIGQKMPAWVLTGFEDYFKRIQPFVQTQVIELPMAKRGKNDSEADILKYCQIEGESILNALKPNETLIALEVGGRELSTEKLADTMKQWMLEGNDVALAIGGPDGLSDQVRKAAAWHWSLSKLTMPHPLVRILLIEQLYRAMSINHNHPYHRA
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBIA_METST
Sequence: MKRVVLTGTGSGVGKTTIATGIMKALSDEHKIQPFKVGPDYIDPSYHNCATGVSSRNLDSFFMSDGQIRQSFKNGMTSSHADYGIIEGVRGLYEGISPTNDIGSTSSIAKALNSPVILIINSRSLVRSAAAMTLGFKALDSRIDIEGVILNNVKSQKHYLKTKEAVEKLANTRVLGGIERDNSISMEQRHLGLIPAVEQERISGLVEKWGELIRENIDLDALMEIMDNSNPIINEYEPIWSPNKTKHKTRIAVPFDEAFNFYYKENLEALEYNNAKIEYFSPIHDEQLPSVDALYIGGGYPEIFKKELSKNTTMLESIKEFSQDNHPIYAECGGLMYLCKTIDSLPMVDVFPYHSMLTKRVQGLSYTIAHVQRDNPILKKNTTYHGHEFHYSKVEYTGSNSNDFAFSMRRGVGITGKYDGLLKNNTLASYIHTHTACLPDFGYNFTQSAYENK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.  Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation.  Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source.
What are the official names of this protein?
Cobyrinate a,c-diamide synthase, Cobyrinic acid a,c-diamide synthetase, Ni-sirohydrochlorin a,c-diamide synthase, Ni-sirohydrochlorin a,c-diamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CbiA family.
Protein: TNR4_KLEPN
Sequence: MRIFGYARVSTSQQSLDIQIRAVKDAGVKANRIFTDKASGSSTDREGLDLLRMKVEEGDVILVKKLDRLGRDTADMIQLIKEFDAQGVAVRFIDDGISTDGDMGQMVVTILSAVAQAERRRILERTNEGRQEAKLKGIKFGRRRTVDRNVVLTLHQKGTGATEIAHQLSIARSTVYKILEDERAS
What is the function of this protein?
Resolvase catalyzes the resolution (a site-specific recombination) of the cointegrated replicon to yield the final transposition products.
What are the official names of this protein?
Transposon Tn1331 resolvase.
What is the protein family that this protein belongs to?
Belongs to the site-specific recombinase resolvase family.
Protein: PSBM_PROM9
Sequence: METTNFGFIASLLFVGVPTIFLIGLFISTQDGEKSSFFSDSSKGKLGPKR
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface.
What are the official names of this protein?
Photosystem II reaction center protein M, PSII-M.
What is the protein family that this protein belongs to?
Belongs to the PsbM family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.