PharMolix/UniProtQA huggingface dataset:
Protein: RL17_STRP8
Sequence: MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTVEKMITLGKRGDLHARRQAAAYVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAERNGGYTRILKTEPRRGDAAPMAIIELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: RL16_ACIF2
Sequence: MLQPKRTKFRKQHKGRNRGVATRGSKVSFGEFGLKAVGRGRITARQLEAARRAISRHVKRGGRIWIRIFPDKPISKKPAEVRMGKGKGNPEYWVALIQPGKVLYEMEGVTEEVAREAFALGAAKLPVQTAFVSRRVMG
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: LGT_ACIBC
Sequence: MLTYPNIDPVAIHLGPLQVHWYGLMYLLAFLCAWGLASYRAKQRDGWTSDMVSDLVFYGALGVVLGGRIGYVLFYEFDKFLENPIWLFQVWTGGMSFHGGFLGVMIAMLFWCKKYQKTWFQTLDFIAPCVPTGLMFGRIGNFIGGELYGRAVTDPNYPFGMIFPTDPLHLVRHPSQIYQALCEGLLLFIILWWFSSKPRPRMAVSALFLMGYGVARFVMEFFRQPDADQGFILFGWMTKGQILTVPMLLIGLWMMWYAYQKKIYDWGPQKNS
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SCE3_CENSC
Sequence: MNSLLIIAACLALIGTVWAKEGYIVNYHTGCKYECFKLGDNDYCLRECKLRHGKGSGGYCYAFGCWCTHLYEQAVVWPLPKKKCNGK
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
What are the official names of this protein?
Beta-toxin CsE3, Neurotoxin E3.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DDRGK_MOUSE
Sequence: MVGPWVYLVAAVLLIGLILFLTRSRGRAAAADGEPLHNEEERAGAGQVGRSLPQESEEQRTGSRPRRRRDLGSRLQAQRRAQRVAWEDGDENVGQTVIPAQEEEGIEKPAEVHPTGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLKEEQKEEEERKAQEEQARREHEEYLKLKEAFVVEEEGVSETMTEEQSHSFLTEFINYIKKSKVVLLEDLAFQMGLRTQDAINRIQDLLTEGTLTGVIDDRGKFIYITPEELAAVANFIRQRGRVSITELAQASNSLISWGQDLPAQASA
What is the function of this protein?
Substrate adapter for ufmylation, the covalent attachment of the ubiquitin-like modifier UFM1 to substrate proteins, which plays a key role in reticulophagy (also called ER-phagy) (By similarity).  In response to endoplasmic reticulum stress, promotes recruitment of the E3 UFM1-protein ligase UFL1 to the endoplasmic reticulum membrane: in turn, UFL1 mediates ufmylation of proteins such as RPN1 and RPL26/uL24, promoting reticulophagy of endoplasmic reticulum sheets (By similarity).  Ufmylation-dependent reticulophagy inhibits the unfolded protein response (UPR) by regulating ERN1/IRE1-alpha stability (PubMed:28128204).  Ufmylation in response to endoplasmic reticulum stress is essential for processes such as hematopoiesis or inflammatory response (PubMed:30701081).  Required for TRIP4 ufmylation, thereby regulating nuclear receptors-mediated transcription (PubMed:28263186).  May play a role in NF-kappa-B-mediated transcription through regulation of the phosphorylation and the degradation of NFKBIA, the inhibitor of NF-kappa-B (PubMed:28263186).  Plays a role in cartilage development through SOX9, inhibiting the ubiquitin-mediated proteasomal degradation of this transcriptional regulator (PubMed:28263186).
What are the official names of this protein?
DDRGK domain-containing protein 1, UFM1-binding and PCI domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the DDRGK1 family.
Protein: NADE_OCEIH
Sequence: MSDLQKTIIEDLHVEPEIDPKQEIRTRVDFLKSYLKKHTFSTGYVLGMSGGQDSTLLSKLTQIAVNELNEENSTNTYQFIGMKLPYGVQKDADDVDDAIKFVEPSKVLTVNIKESVDASVKALDGAGVEISDFLKGNEKARERMKAQYSVAGAFNCFVLGTDHAAEAVTGFYTKHGDGACDLAPLFGLNKRQGKQMLVALNCPEHLYNKKPTADLEDDRPALPDEEALGVTYEQIDEFLEGKEVAEDSKRTIEGHYLKTMHKREGEVTLYDQWWK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: Y5240_DICDI
Sequence: MGAMEGQLWIVFMWVSGVVCGICVLMSENDNIFNNNNNNIIIIIIIIMMIKIMKIIIINNMIIINND
What are the official names of this protein?
Putative uncharacterized transmembrane protein DDB_G0280899.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: AKT1_XENLA
Sequence: MNEVAIVKEGWLHKRGEYIKTWRPRYFLLKSDGTFIGYKERPQDVDQLETPLNNFSVAKCQLMKTERPKPNTFIIRCLQWTTVIERTFHVDSPEEREEWIQVIQHVADNLKKQEEEMMEVRSGDSPSDNSGAEEMEVSHSKPKHKVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERIFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLLPEAKSLLSGLLKKDPKQRLGGGPDDAKEIMQHKFFAGIVWQDVYEKKLVPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDNFEFVDNERRPHFPQFSYSASGNA
What is the function of this protein?
AKT1 is one of several closely related serine/threonine-protein kinases known as the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis.  This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates.  Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported.  Signals downstream of phosphatidylinositol 3-kinase (PI(3)K) to mediate the effects of various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), insulin and insulin-like growth factor I (IGF-I).  Plays a role as a key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation.  Plays a role in glucose transport by mediating insulin-induced translocation of the GLUT4 glucose transporter to the cell surface.  Mediates the antiapoptotic effects of IGF-I.  Mediates insulin-stimulated protein synthesis, partly by playing a role in both insulin-induced phosphorylation of 4E-BP1 and in insulin-induced activation of p70 S6 kinase.  Promotes glycogen synthesis by mediating the insulin-induced activation of glycogen synthase (By similarity).  Required for insulin-stimulated meiotic reinitiation during oocyte maturation.
What are the official names of this protein?
RAC-alpha serine/threonine-protein kinase, Protein kinase Akt-1, xAkt, Protein kinase B, alpha, PKB alpha, RAC-PK-alpha.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Nucleus after activation by integrin-linked protein kinase 1 (ILK1).
Protein: FTSH_LEPBJ
Sequence: MNKNLKNVFFVLIIMMVVLIIAYNYENNAGATKDISYSDFLNMLEPVEGKKPLGKLYKGNVDKYNKIQIEKDVIEGFYIPSEYLESKTAKPVKFRTTVAPLDKDLIASLRKANVSFDARSAEEGKFWSVIGSNILLIVILIGLFWFIMMRQIQSTGNKAFSFGKSKAKMTMDPKVKITFEDVAGCEEAKEELVEIIEFLKDPKKFHAIGARIPTGVLLVGPPGTGKTLLARAVAGEAGVPFFSISGSDFVEMFVGVGASRVRDLFDQGKKNSPCIIFIDEIDAVGRLRGAGLGGGHDEREQTLNQMLVEMDGFEKNEGVIVMAATNRADVLDPALLRPGRFDRQVMVDLPDIKGREEILKVHSRKVPMTSDISLHSIARGTPGFTGADLANLINEGALLAARKNKKRVTQEELEEARDKVMMGPERKSFFISEKEKEVIAYHEAGHAILGTLLPYTEPVHKVTIIPRGRALGLTQSLPKEDKHILPKTYWLDQIIVAMGGFIAEEFKFGVTSTGSSNDIQQASNIARKMVCEWGMSEKLGTVNYSGDQTNVFIGRDMGHSSKYYSEEFAAMIDKEVREIIQTCLNKGRDLVRKNASKFEGLAKALLAKETISHEELMTIVHPANEEGAKKKPEKTVKSKKQNGIKANPAYNE
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: GBA3_HUMAN
Sequence: MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPGIPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQEAAKRAITFHLDLFAKPIFIDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQENKKGELGILQDAEIEFFPDPSWKNVDWIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAHL
What is the function of this protein?
Neutral cytosolic beta-glycosidase with a broad substrate specificity that could play a role in the catabolism of glycosylceramides (PubMed:11389701, PubMed:11784319, PubMed:20728381, PubMed:26724485, PubMed:17595169, PubMed:33361282).  Has a significant glucosylceramidase activity in vitro (PubMed:26724485, PubMed:17595169).  However, that activity is relatively low and its significance in vivo is not clear (PubMed:26724485, PubMed:17595169, PubMed:20728381).  Hydrolyzes galactosylceramides/GalCers, glucosylsphingosines/GlcSphs and galactosylsphingosines/GalSphs (PubMed:17595169).  However, the in vivo relevance of these activities is unclear (PubMed:17595169).  It can also hydrolyze a broad variety of dietary glycosides including phytoestrogens, flavonols, flavones, flavanones and cyanogens in vitro and could therefore play a role in the metabolism of xenobiotics (PubMed:11784319).  Possesses transxylosylase activity in vitro using xylosylated ceramides/XylCers (such as beta-D-xylosyl-(1<->1')-N-acylsphing-4-enine) as xylosyl donors and cholesterol as acceptor (PubMed:33361282).  Could also play a role in the catabolism of cytosolic sialyl free N-glycans (PubMed:26193330).
What are the official names of this protein?
Cytosolic beta-glucosidase, Cytosolic beta-glucosidase-like protein 1, Cytosolic galactosylceramidase, Cytosolic glucosylceramidase, Cytosolic glycosylceramidase, Cytosolic GCase, Glucosidase beta acid 3, Glucosylceramidase beta 3, Klotho-related protein, KLrP.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family. Klotho subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: PTH_METTH
Sequence: MKQVIIVRSDLKMGKGKIAAQACHASIGSFKRTEEDKIRKWELEGSKKVIVSVNSLDELLEIYRAVKEAGISNYLVRDAGHTQIPAGTITCLGIGPDDDEKIDKITGDLKLL
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS2_STAA9
Sequence: MRQKTLDVLEFEKIKSLVANETISDLGLEKVNQMMPATNFETVVFQMEETDEIAQIYNKHRLPSLSGLSKVSAFIHRADIGGVLNVSELNLIKRLIQVQNQFKTFYNQLVEEDEGVKYPILDDKMNQLPVLTDLFHQINETCDTYDLYDNASYELQGIRSKISSTNQRIRQNLDRIVKSQANQKKLSDAIVTVRNERNVIPVKAEYRQDFNGIVHDQSASGQTLYIEPSSVVEMNNQISRLRHDEAIEKERILTQLTGYVAADKDALLVTEQVMGQLDFLIAKARYSRSIKGTKPIFKEERTVYLPKAYHPLLNRETVVANTIEFMEDIETVIITGPNTGGKTVTLKTLGLIIVMAQSGLLIPTLDGSQLSVFKNVYCDIGDEQSIEQSLSTFSSHMTNIVEILKHADKHSLVLFDELGAGTDPSEGAALAMSILDHVRKIGSLVMATTHYPELKAYSYNREGVMNASVEFDVDTLSPTYKLLMGVPGRSNAFDISKKLGLSLNIINKAKTMIGTDEKEINEMIESLERNYKRVETQRLELDRLVKEAEQVHDDLSKQYQQFQNYEKSLIEEAKEKANQKIKAATKEADDIIKDLRQLREQKGADVKEHELIDKKKRLDDHYEAKSIKQNVQKQKYDKIVAGDEVKVLSYGQKGEVLEIVNDEEAIVQMGIIKMKLPIEDLEKKQKEKVKPTKMVTRQNRQTIKTELDLRGYRYEDALIELDQYLDQAVLSNYEQVYIIHGKGTGALQKGVQQHLKKHKSVSDFRGGMPSEGGFGVTVATLK
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: CXCR4_BOVIN
Sequence: MEGIRIFTSDNYTEDDLGSGDYDSMKEPCFREENAHFNRIFLPTVYSIIFLTGIVGNGLVILVMGYQKKLRSMTDKYRLHLSVADLLFVLTLPFWAVDAVANWYFGKFLCKAVHVIYTVNLYSSVLILAFISLDRYLAIVHATNSQKPRKLLAEKVVYVGVWLPAVLLTIPDLIFADIKEVDERYICDRFYPSDLWLVVFQFQHIVVGLLLPGIVILSCYCIIISKLSHSKGYQKRKALKTTVILILTFFACWLPYYIGISIDSFILLEIIQQGCEFESTVHKWISITEALAFFHCCLNPILYAFLGAKFKTSAQHALTSVSRGSSLKILSKGKRGGHSSVSTESESSSFHSS
What is the function of this protein?
Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation.  Involved in the AKT signaling cascade (By similarity).  Plays a role in regulation of cell migration, e. g.  during wound healing.  Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels.  Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes (By similarity).  Involved in hematopoiesis and in cardiac ventricular septum formation.  Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells.  Involved in cerebellar development.  In the CNS, could mediate hippocampal-neuron survival (By similarity).
What are the official names of this protein?
C-X-C chemokine receptor type 4, CXC-R4, CXCR-4, Fusin, LCR1, Leukocyte-derived seven transmembrane domain receptor, LESTR, Stromal cell-derived factor 1 receptor, SDF-1 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction. Early endosome. Late endosome. Lysosome. Note=In unstimulated cells, diffuse pattern on plasma membrane. On agonist stimulation, colocalizes with ITCH at the plasma membrane where it becomes ubiquitinated (By similarity). In the presence of antigen, distributes to the immunological synapse forming at the T-cell-APC contact area, where it localizes at the peripheral and distal supramolecular activation cluster (SMAC) (By similarity).
Protein: FMT_LACDB
Sequence: MNSVIFLGTPQFGATVLEGLIKAGYHILAVVTQPDKKVGRKQKVVYSPVKEVALANDLPLYQPVRLSKSDELDELLQLDADFIITAAFGQFLPTKFLKSAKIAAVNVHGSLLPKYRGGAPIQYAVRNGDAETGVTIMEMVKEMDAGDMYAQASLPIRPDETSGEVFEELAPLGRDLLLETLPKIASGEIVKKPQDPSQVVFSPTISKAEERISLKLTAKEAKNLIRALNPDPGAYLVIKGQRLKVWKAEVADDNTSLPAGHLLTNQGRFAISFAGNTVLNLLEVQPNGKKAMAIKDFLNGQGKKFAAGEKIVDED
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: LEXA_KLEP3
Sequence: MKALTTRQQEVFDLIRDHISQTGMPPTRAEIAQRLGFRSPNAAEEHLKALARKGAIEIVSGASRGIRLLTEEEHGLPLIGRVAAGEPLLAQQHIEGHYQVDPSMFKPNADFLLRVSGMSMKDIGILDGDLLAVHKTQDVRNGQVVVARIDDEVTVKRLKKQGNVVELLPENSEFTPIVVDLRQQSFTIEGLAVGVIRNGEWL
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: TRHO_FRATH
Sequence: MSQIVVCAMYKFVTLEDFEAMRQPLLDTMIKNNVKGTLLLANEGINGTVAGTRESIDNLLAYLKADPRLVDIDYKESYHQEMPFYRSKVKLKKEIVTLGIDEIDPNKICGKYVEPKDWNDLISDPETVLIDTRNEYEIEIGTFKNAINPHTENFREFPQYVDENLDPKKHKKVAMFCTGGIRCEKSTALLKAKGFDEVYHLKGGILKYLEEVPKEKSMWQGECFVFDSRVAVNHDLEKGNYDQCFACRMPITEDDKKRPEYVKGISCHHCYDKVTEKQKARFAEREKQSQLAAEKGFSHVGDEAKKLAQLNKQKKQQAKEAARKKAQQ
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: RL22_ECO45
Sequence: METIAKHRHARSSAQKVRLVADLIRGKKVSQALDILTYTNKKAAVLVKKVLESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: MSCL_METC4
Sequence: MLEEFKKFALRGNVVDLAVGVIIGAAFGAIVNSLVQDVIMPIIGAVTGGLDFSNYYIPLSSKVQDGMPYAEAKKVGAVIGYGQFLTLAVNFTIIAFVLFMVIRAMNVLKSREEAKPKPVAEVPADVKLLGEIRDLLAARRV
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y615_SHEPW
Sequence: MPRPKKCRNLSCRAPYSMLKPNGIPSVELEKIHIDADEFEALNLGDVQKMSQLDAAASMGISRQTFGYLLASARKKVATAITQGHGLVLPQSTDTKREVL
What are the official names of this protein?
UPF0251 protein swp_0615.
What is the protein family that this protein belongs to?
Belongs to the UPF0251 family.
Protein: ACCD_SOLBU
Sequence: MERWGFNSMLFKKEFERRCGLNKSMGSLGPIENTSEDPNLKVKNIHSCSNVDYLFGVKDIWNFISDDTFLVSDRNGDSYSIYFDIENQIFEVDNDHSFLSELESSFSSYRNSSYLNNGFRGEDPYYNSYMSYMYDTQYSWNNHINSCIDNYLQSQICIDTSIISGGESYGDSYIYRAICSGESLNSSENEGSSRRTRTKGSDLTIRESSNDLEVTQKYKHLWVQCENCYGLNYKKFLKSKMNICEQCGYHLKMSSSDRIELLIDPGTWDPMDEDMVSLDPIEFHSEEEPYKDRIDSYQRKTGLTEAVQTGIGQLNGIPVAIGVMDFQFMGGSMGSVVGEKITRLIEHAANQNLPLIIVCASGGARMQEGSLSLMQMAKISSALYDYQLNKKLFYVSILTSPTTGGVTASFGMLGDIIIAEPNAYIAFAGKRVIEQTLNKTVPEGSQAAEYLFQKGLFDLIVPRNLLKSVLSELFKLHAFFPLNQKSSKIK
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: Y3287_YERPE
Sequence: MLRVIIVDDEQPAREDLRERLNEEHGIEIVAECSNALEAIPAIQRLQPDVVFLDIQMPRINGLELASMLNPESMPHIVFVTAYDEYAIRAFEEHAFDYLLKPLDHQRLAKTLTRLSRDLIVKNNLHKVIKPILRHIPCSGHNRIFLLKIEEVEYLSSELSGVHVVGTVQSGYTQLSLKTLEEKTPFIRCHRQYMVNTEQLGEIQLMDNGAAEVITRSGKHIPVSRRYLKSLKEKLGIA
What are the official names of this protein?
Uncharacterized response regulatory protein YPO3287/y0902/YP_0397.
Protein: HYPA_RHOCA
Sequence: MHEMSIVEGIRTAIEEAARANGFAKVTRVRLEIGRLAGVERAALDFAFDVVLRGSLAEGAAVQIIDLPGQAACFDCGKTVEIEHRLDICPECGGTRLLVQGGDEMRIKDLEVL
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA, Protein HupL.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: MURC_LEVBA
Sequence: MDNATVYHFVGIKGSGMSALALILHDKGFKVQGSDITQYTFTQRGLEQAGIDVMAFDEANIHEGLTVIAGNSFTDDHPEIKKAREMGLPVYRYHEFLGHLIEGYTSIGVAGAHGKTSTTGLLAHVLSGVAPTSYLIGDGSGKGTPNARFFVYEADEYRRHFLATKPDYAIMTNIDFDHPDYYTGIDDVYSAFETLAKQVKKGIFAWGDDPELRKLKTDVPVYYYGTSDRDDFQARNIKRSTTGSTFDVYHDDEFLGNFEIHLFGEHNVLNSLAVIAVAYFEKVNMDEIKHELADFKGVKRRFTERKLADMTIIDDYAHHPSEIKATLDAARQKYPDKEIIAVFQPHTFSRTIALMDDFAKSLNLADKVFLTNIFSSARETQGAVSSKDLAQKIVKGGEILTVDNMSPLLDFHDAVVVFMGAGDVQKYERAYEELLSHLSLKNN
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31_ESCF3
Sequence: MKKDIHPKYEEITASCSCGNVMKIRSTVGHDLNLDVCSKCHPFFTGKQRDVATGGRVDRFNKRFNIPGSK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: RIBX_SHIFL
Sequence: MPVRAQRIQHVMQDTIINFYSTSDDYGDFSNFAARPIKVDGNTWPTSEHYFQAQKFLDEKYREEIRRVSSPMVAARMGRNRSKPLRKNWESVKEQVMRKALRAKFEQHAELRVLLLATAPAKLVEHTENDAYWGDGGNGKGKNRLGYLLMELREQLAIEK
What is the function of this protein?
Catalyzes the hydrolysis of the N-glycosidic bond in the first two intermediates of riboflavin biosynthesis, which are highly reactive metabolites, yielding relatively innocuous products.  Thus, can divert a surplus of harmful intermediates into relatively harmless products and pre-empt the damage these intermediates would otherwise do.  Helps maintain flavin levels.  May act on other substrates in vivo.  Has no activity against GTP, nucleoside monophosphates or ADP-ribose.  Is Required for swarming motility.
What are the official names of this protein?
N-glycosidase YbiA, Riboflavin biosynthesis intermediates N-glycosidase.
What is the protein family that this protein belongs to?
Belongs to the YbiA family.
Protein: COBS_VIBVU
Sequence: MKTWQYQYQLFCLAVSFFSRLPVPKSTPYSDERMNQAGRYFALVGTLLGLLCVLVYAFASLFFPYQVAIVLMMAFSLLLTGAFHEDGLTDMADGIGGGMTLDKRLTIMKDSRIGTYGSATLTMALIGKFVFLTTLARQPDFGLMIVVAYTLSRAVAATLIYDMPYVSDSDTSKSKPLANAQSSTELAILILTGVLAAISLGLGVGLLLILFAILFRWAFKRWLLARLGGFTGDCLGGAQQLMELGIYLVLIAVVQ
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.