PharMolix/UniProtQA huggingface dataset:
Protein: PHNY_GIMM8
Sequence: MNTTLTDSQLDRWNQTGYIKLPEFLSEAETQNLREWVEEISAWPADDEKWMHHFEQTPSGVRPARTEYILAFHAGIRQLLTQGKIPDCAGALMGEPAILYKEKINYKYPGGGGYAAHQDAPAYEFIRNHITCSIAVDAATPENGCLFFTPELHQRGLLHLDKNGCIDREYADTLDWEPVPMQPGDALFFSSYAPHKSPPNETQQPRRTLYLTYNALAEGDLREEYYADKRRSFAQVDTTGGEKLKISKIGHFDGKPAQQT
What is the function of this protein?
Part of an oxidative pathway for utilization of methylphosphonic acid as a phosphate source (PubMed:30810303).  Catalyzes the conversion of methylphosphonic acid to hydroxymethylphosphonic acid (PubMed:30810303).  Is specific for the hydroxylation of methylphosphonate (PubMed:30810303).
What are the official names of this protein?
Methylphosphonate hydroxylase, GmPhnY*.
What is the protein family that this protein belongs to?
Belongs to the PhyH family.
Protein: RK16_OSTTA
Sequence: MLSPKRTKYRKPHRGNRKGQALRGNKISFGDFALQALEPGWITSRQIEAGRRAMSRYAKRGGKLWIRMFPDRSITARAAETRMGAGKGAPDYWVCIVKPGKILYELAGVPETIARASMRIAAYKMPVKTKFLVRDEYVAPQ
What are the official names of this protein?
50S ribosomal protein L16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HIS2_NITMU
Sequence: MSDPDILFRLAETIEARKQSDPHASYVAKLLHDGRDKILKKIAEESAEVLLASKDGDSTHVVRETADLWFHCLVLLAHHNLKLGDVLDELRRREGVSGIDEKAARKAGLADNGIGRMNQDK
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCNK_BACSU
Sequence: MLPINRQQHILKWLKEEGSLRISDISARFGVSEMTVYRDVNQLVQSNQVIKTAGGITLPVRTPQTDHMCSYCLKPVNQAHSVQLITVNQDIEQLCCAHCAFLRYADKTEEVSHLICRDFLLQTTVSAGSAYFVVNAELNLHCCQPQAIPFATLDHAERFQKGFGGAVCTFDQALEDMLQDRKKRCTCTKK
What is the function of this protein?
May act as a negative transcriptional regulator of ycnJ in the presence of copper.  May use copper as a corepressor.
What are the official names of this protein?
HTH-type transcriptional repressor YcnK.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WZYE_YERPS
Sequence: MTLGQFGGLFCIYLIAVIFILTLTYQEFRRVKFNFNVLFSMLYLLTFYFGFPLTCMLVFQFGVAVVPVEYLLYAMLSATAFYGIYYVTYKTRLRQPRSQPRTPIFTMNRVETNLTWVLLALVAVGTVGIFFMQNGFLLFKLDSYSKIFSSDVSGVALKRFFYFFIPAMLVVYFLKQDRRAWFFFLASTVAFGILTYVIVGGTRANIIIAFSLFLFIGIVRGWITLWMLAAAGVFGIVGMFWLALKRYGLDVNGAEAFYTFLYLTRDTFSPWENLGLLLQNYDKIDFQGLAPIVRDFYVFIPSALWPERPDLVLNTANYFTWDVLDNHSGLAISPTLIGSLVVMGGVLFIPLGAIVVGLIIKWFDWLYEQGKAESNRYKAAILQSFCFGAVFNIIVLAREGLDSFVSRVVFFCVIFGACLVLAKLLYWLFDTAGLIKRQGIKSNRLSTPNAGNQL
What is the function of this protein?
Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units.
What are the official names of this protein?
Probable ECA polymerase.
What is the protein family that this protein belongs to?
Belongs to the WzyE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PROA_CHLSY
Sequence: MVDLEAIGRRAKTAARALAKLSTEQKNAALCAIADGLLARQDKILAANAADVADAEKGGTPPAIVDRMLLTPARLAAIAGDCRQVASLPDPVGEIFDRRELPSGLRLYKRRVPIGVIGAIYEARPNVTVDIASLCLKAGNAVILRGGSDIARSVAATTEVIALALEQAGLPAFAVQSIIDPDRELVRQLLRLDRYVDMIIPRGGAGLHRFCVENATVPVIVGGMGVSHIYVEPSADFARAVPVIVNAKVQRPGACNALDTLLVHRAAASTFLPLVAAALAQHGVELRCDLEALAILADAPGHEAWNLKPASPTDFGCEFLALIVAIKIVGSIDEALDHIALYGGHSEAILTGDPISAERFTREVDATAVFVNASTRFNDGGQFGLGAEVAISTNRLHARGPMGLQELTTYTWIGEGDYLVRA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ESPB_MYCTU
Sequence: MTQSQTVTVDQQEILNRANEVEAPMADPPTDVPITPCELTAAKNAAQQLVLSADNMREYLAAGAKERQRLATSLRNAAKAYGEVDEEAATALDNDGEGTVQAESAGAVGGDSSAELTDTPRVATAGEPNFMDLKEAARKLETGDQGASLAHFADGWNTFNLTLQGDVKRFRGFDNWEGDAATACEASLDQQRQWILHMAKLSAAMAKQAQYVAQLHVWARREHPTYEDIVGLERLYAENPSARDQILPVYAEYQQRSEKVLTEYNNKAALEPVNPPKPPPAIKIDPPPPPQEQGLIPGFLMPPSDGSGVTPGTGMPAAPMVPPTGSPGGGLPADTAAQLTSAGREAAALSGDVAVKAASLGGGGGGGVPSAPLGSAIGGAESVRPAGAGDIAGLGQGRAGGGAALGGGGMGMPMGAAHQGQGGAKSKGSQQEDEALYTEDRAWTEAVIGNRRRQDSKESK
What is the function of this protein?
Required for host-cell death and may support an EsxA-independent virulence function (PubMed:23869560).  Secreted processed form of EspB binds to phosphatidic acid and phosphatidylserine (PubMed:23869560).  Inhibits IFN-gamma-induced autophagy in murine macrophages (PubMed:25641595).
What are the official names of this protein?
ESX-1 secretion-associated protein EspB, Antigen MTB48.
What is the protein family that this protein belongs to?
Belongs to the EspB family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the ESX-1 / type VII secretion system (T7SS) (PubMed:17676952). Secretion requires both EspK and EccCb1, but not EspA, EspC and EspD (PubMed:17676952, PubMed:23869560).
Protein: APTA_ACTSZ
Sequence: MNPYNLSYDELEKKAKAIRRKIVVLNANSPAGGHTGADLSQVEILTSLYFRVLNNDPKDLINPERDIYIQSKGHGAGGYYCCLAEAGYIPEDWLPTYQHSDSKLPGHPVKHKTPGVELNTGALGHGLPVAVGLAIAAKKSGSKRKIYVLTGDGELGEGSNWEAALTAAQYKLDNLIIINDKNKLQLAGFTKDILCTDPLDKKWEAFGMEVHECQGNDIRSVVDTLESIQPNGKPHVVIANTTKGAGISFIEGRPEWHHKVPKGDEVELALEELKDE
What is the function of this protein?
Involved in catabolism of D-apiose.  Catalyzes the transfer of the glycolaldehyde group from apulose-4-phosphate to D-glyceraldehyde 3-phosphate, generating dihydroxyacetone phosphate and D-xylulose-5-phosphate.
What are the official names of this protein?
Apulose-4-phosphate transketolase subunit A, Apulose-4-phosphate transketolase N-terminal subunit.
What is the protein family that this protein belongs to?
Belongs to the transketolase family.
Protein: Y1300_MYCBO
Sequence: MTTMITLRRRFAVAVAGVATAAATTVTLAPAPANAADVYGAIAYSGNGSWGRSWDYPTRAAAEATAVKSCGYSDCKVLTSFTACGAVAANDRAYQGGVGPTLAAAMKDALTKLGGGYIDTWACN
What are the official names of this protein?
Protein Mb1300c.
What is the protein family that this protein belongs to?
To M.tuberculosis Rv1813c.
Protein: RLMM_SHEWM
Sequence: MINLFLYCRSGYEKECAAEIQHRAAELEIGGFVKTNKKDGYVIFQCFQAGDANILAQKIKLDSLIFARQMFAAKELLKNLPEHDRITPIMEALSDVRNAGELRVETPDTNEAKERTAFCRKFTVPLRQKLKNAGNLLKKENSSRPIIHVCFVASGTAYVGFSFSNNSSPYPMGIPRLKMASDAPSRSTLKLDEAFIHFIPEEEQEQRLSSGMNAVDLGACPGGWTYQLVRRGMFVAAVDNGPMDEGLMETGQVKHYQADGFRFEPPRKNIYWLVCDMIEKPSRVAELIEAWAINGWFKEAMFNLKLPMKSRYQDVSTILETMATVLEENEIKNFSIKCKHLYHDRDEVTVYLSLNPTQ
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BP09_BPT4
Sequence: MFIQEPKKLIDTGEIGNASTGDILFDGGNKINSDFNAIYNAFGDQRKMAVANGTGADGQIIHATGYYQKHSITEYATPVKVGTRHDIDTSTVGVKVIIERGELGDCVEFINSNGSISVTNPLTIQAIDSIKGVSGNLVVTSPYSKVTLRCISSDNSTSVWNYSIESMFGQKESPAEGTWNISTSGSVDIPLFHRTEYNMAKLLVTCQSVDGRKIKTAEINILVDTVNSEVISSEYAVMRVGNETEEDEIANIAFSIKENYVTATISSSTVGMRAAVKVIATQKIGVAQ
What is the function of this protein?
Peripheral baseplate protein that is part of the tail fiber network (PubMed:10545330, PubMed:27193680).  Connects the long tail fibers to the baseplate and, after virus attachment to a host cell, probably changes its conformation to trigger the signal for tail contraction (PubMed:10545330).  Involved in the tail assembly (PubMed:21129200).
What are the official names of this protein?
Baseplate protein gp9, Gene product 9, gp9.
What are the subcellular locations of this protein?
Virion. Note=Present in 18 copies in the baseplate.
Protein: SMG_ECODH
Sequence: MFDVLMYLFETYIHTEAELRVDQDKLEQDLTDAGFEREDIYNALLWLEKLADYQEGLAEPMQLASDPLSMRIYTPEECERLDASCRGFLLFLEQIQVLNLETREMVIERVLALDNAEFELDDLKWVILMVLFNIPGCENAYQQMEELLFEVNEGMLH
What are the official names of this protein?
Protein Smg.
What is the protein family that this protein belongs to?
Belongs to the Smg family.
Protein: EFTU_CAMFF
Sequence: MAKEKFSRNKPHVNIGTIGHVDHGKTTLTAAISAVLSRRGLAELKDYDNIDNAPEEKERGITIATSHIEYETENRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLSRQVGVPYIVVFMNKADMVDDAELLELVEMEIRELLSEYDFPGDDTPIISGSALQALEEAKAGNDGEWSAKIMDLMAAVDSYIPTPVRATDKDFLMPIEDVFSISGRGTVVTGRIEKGIVKVGDTIEIVGIRDTQTTTVTGVEMFRKEMDQGEAGDNVGVLLRGTKKEDVERGMVLCKPKSITPHTKFEGEVYILTKEEGGRHTPFFNNYRPQFYVRTTDVTGSITLPEGTEMVMPGDNLKITVELINPVALEDGTRFAIREGGRTVGSGVVSKIIA
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOF_PSEVU
Sequence: MSWQQRIDTALATRRAADALRTRRVVEQGAGRWLTVGDSRYCNFSSNDYLGLSQHPAIVRAWQQGAEQYGVGSGGSGHVSGYTRAHYALESELAEWLGYPRALLFISGFAANQAVIAALTGKEDRIVADKLSHASLLEAASFSPAQLRRFAHNDVSQLAALLDKPCDGQQLAVTEGVFSMDGDSAPLAAIAEQVRRAGAWLLVDDAHGIAVTGHKGRGSCQQQEVKPELLVVTFGKGFGVSGAAVLCSEAVATYFEQFARHLIYSTSMPPAQAVALSAALSVIRGEEGDQRRTALAGLIQRFRHGAAALPGRITHSQSAIQPLIVGDNSRALSLAERLRQKGCWVTAIRPPTVPAGTARLRLTLTAAHQPEDIDRLLEVLHESGE
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: RS2_RUMCH
Sequence: MAVISMKQLLEAGVHFGHQTRRWNPKMAEYIFTERNGIYIIDLQKTVKKVDDAYFFIREIAMNGQDVLFVGTKKQAQDSIREEAERSGQFFVNNRWLGGMLTNFKTITKRINRLHQLNAMETDGTFEVLPKKEVSKLKKEMADLEKNLGGIKNMKKLPGAMFVVDPRKERNAILEAKRLGIPVVAIVDTNCDPDEVDFVIPGNDDAIRAVKLIAAKMADAVIEGRQGEQLAETPVETAEVAEEAQVAVEAAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: SYS_NITMS
Sequence: MLDPKLLKEKPQVIRDMLKARAVDFDLDGLIESDQKRREFIIKTDEFKKRRNEIGNEIAQKKKAGEDTSTILDEMKNVSAELAKLESQQEEIESKYAKLAFTVPNLVHESVPVGPDDTANKEMRKWGEIPQFDFKINDHIDMSENLDLVDLERAAKVAGARFYYLKNDLVRLNQSLIHFALDFLAEKEYSLVQPPYMINRSSMEGAVIADDFEEVIYKVEEEDLYMIGTSEHAMAAMHSKEIIEGKDLPIRYAGVSPCFRKEAGAHGRDQKGIFRVHQFDKIEQFVYARPEDSWKEHEKMLAVAEEFYQKLEIPHRVMLLSTGDMGKISAKTYDIEAWMAGQNSYREIVSCSNCLDYQARRLKIRFRDKTNEDTQYIHTLNSTLVATTRVLVSIMENFQTKDGHIKIPQVLQSYMGNQKEI
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TATB_PSEPF
Sequence: MFGISFSELLLVGLVALLVLGPERLPGAARTAGLWVGRLKRSFNAIKQEVEREIGADEIRRQLHNEHILSLEQEARKIFTPVQQEPTPVEHVGEQTIHSPAAPTPAAPAVAPTESAPVVAPASVEHVAQTAAPTTPAPNDTTQPPRAP
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: Y1385_JANMA
Sequence: MLIVLSPAKTLDYDTPAHTEISSKPDFIKQSAELIKILRQSSPAQIASLMRISDPLASLNANRFAAWSPKFTQKNSKQAMLAFNGDVYEGLDAASMDAKQLAYAQSHIRILSGLYGVLRPLDLMQPYRLEMGTRLANAAGKDLYAFWGNTVTETLNQRIAEQQSEALVNLASEEYFKVVKPALLKAPVITPVFQDWKNGQYKIISFYAKRARGLMARYAATKGIKRPEELKSFDVDGYEFDAAASNEKTWMFRRKVGI
What are the official names of this protein?
UPF0246 protein mma_1385.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: Y2306_MYCTO
Sequence: MTRVALLTTGRELSQAAPPARARTPLPVPTPRGERPDDGGHAPHRDRRVNQRRRQVGDRRAQRGVDEHPWRRPDERPNDHLPQRNSERPEGVRGQRIRDAGDEALTDHRPQSAPFDLCIEAMGAIDTQQRLGVIPACAPAEKAGRVTKVSSSGPNSTPLPAARIGPGTNNAPSAADTTTYARGAIGPVATTIALRTPSTWMTRATATR
What are the official names of this protein?
Uncharacterized protein MT2363.
Protein: AMYG_SCHPO
Sequence: MRTYWLFLLLGGVVSAESLLSPNKRSKEASMDEWTDQQKGIAMGHMLNNIGDSGMHAKDINPGCIIASPSTDSPDYYYQWVRDSALTIMTILDRFFEGDKGLEPIIVKYMDEMVRLQKVPNPSGDFYAGGLGEPKFNVDGTSYDGDWGRPQNDSPALRAIAFIKYMNYLFENGKEVHEVTVWIEAVLADLDYTANHWTEASFDLWEEIKDVHYFTLAVQKRAMQDGTAFAKRIGAPDQAALYQRTIEPIDLKLGEFWDPGMGVIKGYKGRVDRSGLDCSTLLASLYSNEFDMHILPTLLKLQETMTRDYPVNQGWKQAMGRYPEDVYDGVSKSIGNPWFICTSSAAEIIYKAIAYYDNKGLPELTEYNIHFFMKFAEFGDPYNWSVIRKNMHTYADNFLKAVAEFQHPNGSMSEQFSRDDGHQKGARDLTWSYSSLLNAIYRREAIKGSV
What are the official names of this protein?
Probable glucoamylase, 1,4-alpha-D-glucan glucohydrolase, Glucan 1,4-alpha-glucosidase, Meiotic expression up-regulated protein 17.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 15 family.
Protein: BACR_HALHP
Sequence: IWLWLGTAGMFLGMLYFIARGWGETDSRRQKFYIATILITAIAFVNYLAMALGFGLTIVEFAGEEHPIYWARYSDWLFTTPLLLYDLGLLAGADRNTITSLVSLDVLMIGTGLVATLSAGSGVLSAGAERLVWWGISTAFLLVLLYFLFSSLSGRVADLPSDTRSTFKTLRNLVTVVWLVYPVWWLIGTEGIGLVGIGIETAGFMVIDLTA
What is the function of this protein?
Light-driven proton pump.
What are the official names of this protein?
Bacteriorhodopsin, BR.
What is the protein family that this protein belongs to?
Belongs to the archaeal/bacterial/fungal opsin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PIT1_RAT
Sequence: MSCQPFTSADTFIPLNSDASAALPLRMHHSAAEGLPASNHATNVMSTATGLHYSVPSCHYGNQPSTYGVMAGTLTPCLYKFPDHTLSHGFPPLHQPLLAEDPTASEFKQELRRKSKLVEEPIDMDSPEIRELEQFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQLSFKNACKLKAILSKWLEEAEQVGALYNEKVGANERKRKRRTTISIAAKDALERHFGEHSKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKTSLNQSLFSISKEHLECR
What is the function of this protein?
Transcription factor involved in the specification of the lactotrope, somatotrope, and thyrotrope phenotypes in the developing anterior pituitary.  Activates growth hormone and prolactin genes.  Specifically binds to the consensus sequence 5'-TAAAT-3'.
What are the official names of this protein?
Pituitary-specific positive transcription factor 1, PIT-1, Growth hormone factor 1, GHF-1.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: C42S2_RAT
Sequence: MSEFWLCFNCCIAEQPQPRRRRIDRSMIGEPTNFVHTAHVGSGDLFSGMNSVSSIQNQMQSKGGYGGGMPANVQMQLVDTKAG
What is the function of this protein?
Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly.  Alters CDC42-induced cell shape changes.  In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse.  May play a role in early contractile events in phagocytosis in macrophages (By similarity).
What are the official names of this protein?
CDC42 small effector protein 2.
What is the protein family that this protein belongs to?
Belongs to the CDC42SE/SPEC family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell membrane; Lipid-anchor. Cell projection, phagocytic cup. Note=Recruited to the activated TCR prior actin polymerization. Localizes at the phagocytic cup of macrophages.
Protein: SPRR4_MOUSE
Sequence: MPSHQHQNQQQCTPQAQQQQVKQPCQPPPTKCQEACVPKTKDPCVPQAKKQCPARSTTNPAQEKCPAQQDPKCKQK
What is the function of this protein?
Cross-linked envelope protein of keratinocytes.  Involved in UV-induced cornification (By similarity).
What are the official names of this protein?
Small proline-rich protein 4.
What is the protein family that this protein belongs to?
Belongs to the cornifin (SPRR) family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cell cortex. Note=Translocates to the cell periphery of keratinocytes and is integrated into both rigid and fragile cornified envelopes.
Protein: RBM10_MOUSE
Sequence: MEYERRGGRGDRTGRYGATDRSQDDSGENRSRDHDYRDMDYRSYPREYGSQEGKHEYDDSSEEQSAEDSYEASPGSETQRRRRRRHRHSPTGPPGFPRDGDYRDQDYRTEQGEEEEEEDEEEEEEKASNIVMLRMLPQAATEDDIRGQLQSHGVQAREVRLMRNKSSGQSRGFAFVEFSHLQDATRWMEANQHSLNILGQKVSMHYSDPKPKINEDWLCNKCGVQNFKRREKCFKCGVPKSEAEQKLPLGTRLDQQALPLGGRELSQGLLPLPQPYQAQGVLTSQALSQGSEPSSENANDTIILRNLNPHSTMDSILGALAPYAVLSSSNVRVIKDKQTQLNRGFAFIQLSTIVEAAQLLQILQALHPPLTIDGKTINVEFAKGSKRDMASNEGSRINAASVASTAIAAAQWAISQASQGGESAWAAPEEPPVDYSYYQQDEGYGSSQGTDSLYAHGYLKNSKGPGMTGTKGDPAGTGPEASLEAGADSVSLQAFSRAQPGAAPGLYQQSAEGSSGQSTATNSQSYTIISPAVLKAELQSPTQPSSSAFPPATSPTAPEAYSQYPVPDVSTYQYDETSGYYYDPQTGLYYDPNSQYYYNAQSQQYLYWDGERRTYIPALEQSADGHKDTGASSKEGKEKKEKHKTKTAQQIAKDMERWARSLNKQKENFKNSFQPISALRDDERRESATADAGYAILEKKGALAERQHTSMDLPKLASDDRPSPPRGLVAAYSGESDSEEEQERGGPEREEKLTDWQKLACLLCRRQFPSKEALIRHQQLSGLHKQNLEIHRRAHLSENELEALEKNDMEQMKYRDRAAERREKYGIPEPPEPKRRKYGGISTASVDFEQPTRDGLGSDNIGSRMLQAMGWKEGSGLGRKKQGIVTPIEAQTRVRGSGLGARGSSYGVTSTESYKETLHKTMVTRFNEAQ
What is the function of this protein?
Not known.  Binds to RNA homopolymers, with a preference for poly(G) and poly(U) and little for poly(A) (By similarity).  May bind to specific miRNA hairpins (By similarity).
What are the official names of this protein?
RNA-binding protein 10, RNA-binding motif protein 10.
What are the subcellular locations of this protein?
Nucleus.
Protein: NIRD_STUST
Sequence: MHIDALSRRLIDRYQHGMPLCAEPYRAMAEELGCSEGEVLACLEQLQEDGGLSRIGPVFEHSRAGASTLVALAVPEARLEQVAARINAFPEVNHNYLREHRYNLWFVLTGPDRAHIDALLAEIEADTGLVPLDLPMLHAFRIDLGFPLGDPS
What is the function of this protein?
Involved in heme d1 biosynthesis.  Catalyzes the decarboxylation of siroheme into didecarboxysiroheme.
What are the official names of this protein?
Siroheme decarboxylase NirD subunit.
What is the protein family that this protein belongs to?
Belongs to the Ahb/Nir family.
Protein: BIOD_BURM9
Sequence: MSAPLSLFVTGTDTEIGKTFVSAALLHGFARAGLRAAAMKPVAAGAYERDGAWRNEDADQLDAAANVALPAAIRTPFLLKAPAAPHIVAAREGVALDIGTIVDAHRRACEMADVIVVEGVGGVRVPLADTRDTADLAVALGLPVVLVVGVRLGCISHALLTAEAIAARGLPLAGWVANRIDPAMPFADDNIDTLRAWLEREHRAPLLGALAHMSPPSPDAASHALDVNLLLNALRAAAPR
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_METRJ
Sequence: MPRTHAIEDYRNFGIMAHIDAGKTTTTERILYYTGKSHKIGEVHEGAATMDWMAQEQERGITITSAATTCFWRDKRLNIIDTPGHVDFTIEVERSLRVLDGAVCVLDGNQGVEPQTETVWRQADKYDVPRVVFVNKMDKIGADFFKCVADIIDRVAGKPVCLQLPIGAESSFQGVIDLIKMKAIVWSGEALGANFDETEIPADLKDQAVEYRTKLVEACVELDDDAMSAYLDGNEPDEATMRTLVRKAVQLRAFHPVLCGSAFKNKGVQPLLDAVVDYLPSPADRGEIKGIDFKTEEETVRHPSDSDPFSMLAFKIMDDPHVGTITFCRVYSGKVETGANVLNSSRDKKERVGRMLLMHANNREDIKEAFAGDIVALAGLKDTRTGDTLCDPQKAVILEKMEFPEPVIEIAVEPKSKADQEKLGIALSKLAAEDPSFRVSTDQESGQTILKGMGELHLDIKVDILRRTYKVDANIGQPQVAYREKLTRRQEIDYTHKKQTGGTGQFARVKFVVEPNEPGAGFSFESKIVGGAVPKEYIPGVEKGLNSVLGAGVLAGFPVVDVKVELVDGAYHDVDSSALAFEIASRAAFREALQKGGSVLLEPVMKVEVVSPEEYTGSVIGDLNARRGQIQGQDMRGNANVINAMVPLANMFGYVNQLRSFSQGRANFTMQFDHYEEVPRGEADKVIAKYA
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATA2_YEASX
Sequence: MRSIENDRSNYQLTQKNKSADGLVFNVVTQDMINKSTKPYRGHRFTKENVRILESWFAKNIENPYLDTKGLENLMKNTSLSRIQIKNWVSNRRRKEKTITIAPELADLLSGEPLAKKKE
What is the function of this protein?
Probably not a functional protein.  Cells lacking A2 show no obvious alterations in mating, sporulation and cell growth.
What are the official names of this protein?
Putative mating-type protein A2, MATa2 protein.
What is the protein family that this protein belongs to?
Belongs to the TALE/M-ATYP homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LPXH_SHESA
Sequence: MRTLFIGDLHLSADRLDITQAFNRFLDTELDDADALYILGDLFEVWVGDDLAAPFALELARKLNQVSQRLPIYFIHGNRDFMLGKQFADVAGMQMLPEVTCLDLYGVNTVILHGDSLCTLDKAYQRFRKLRSFAFARWLYSCLPKKKRQAIANKIRSNSQSSNQQKSYVIMDVEPSAVDALFAQSHCKQMIHGHTHRPAIHEFTNGCKRIVVGDWYEQGSVLVVSSDGVDLKSLPFDAS
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HEM6_VIBVU
Sequence: MSTIDKEAVKLYLMQLQDQICQRLEQEDGKATFIEDAWYREPGDRLGGGGRTRVMRDGNVFEQGGVNFSHVQGNAMPASATAHRPELAGRRFEAMGVSLVMHPHNPYVPTSHANVRFFIAEKEGEAPIWWFGGGFDLTPFYPFEEDCQFWHNTAKEVCAPFGADVYAQHKAWCDDYFYLPHRGETRGIGGLFFDDLNQWEFDKCFDYIKAVGEGYCDAYLPIVERRKVTEYGEREREFQLYRRGRYVEFNLVYDRGTLFGLQSGGRTESILMSMPPLARWEYSYEPQADSPEASLYQHYLKPREW
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.