PharMolix/UniProtQA huggingface dataset:
Protein: DBNLB_XENLA
Sequence: MSVNLSKNGAALQAAYKDVLDEKTKTDWALYTYEGNSNDIRLAETGDGGLEELVEELSSGKVMYAFCRVKDPNSGLPKFVLINWTGEGVKDARKGMCANHVSTMASFLKGAHVTINARAEEDVEPESIMEKVAKASGANYNFHKESNRGNEGPQGPVGSVYQKTNAMSEIKRVGKENFWAKAEKDEEERRIEEHRRANVEKDRLERERKEREQREAEERERRFRERSKEIDGHRKQQEEVEKQQTVPASQRSVNPREMFLQKERSLPESGSVSAQPEQFTASQQEEENIYQDATENQNIYEDTPQEDPVYETGVAEDSGMCARALYDYQAADDTEISFDPDDVIIQIEMIDDGWWRGVAPSGHFGMFPANYVELLE
What is the function of this protein?
Adapter protein that binds F-actin and dynamin, and thereby plays a role in receptor-mediated endocytosis.  Plays a role in the reorganization of the actin cytoskeleton, formation of cell projections, such as neurites, in neuron morphogenesis and synapse formation.  Does not bind G-actin and promote actin polymerization by itself, but excerts its functions by interaction with other proteins.  Required for the formation of organized podosome rosettes (By similarity).
What are the official names of this protein?
Drebrin-like protein B.
What is the protein family that this protein belongs to?
Belongs to the ABP1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Cell projection, ruffle. Cytoplasm, cell cortex. Cytoplasm, cytosol. Synapse. Perikaryon. Cell projection, neuron projection. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, podosome. Early endosome. Cell projection, dendrite. Postsynaptic density.
Protein: YOZN_BACSU
Sequence: MVQPTPYININIFMLKINSFENASAVNVGQNLLAEWQNSDKKNQGYGQNFGDASGFMGTRSHVDDRDQIDSPASFESEAVNSSIKRK
What are the official names of this protein?
Uncharacterized protein YozN.
Protein: MRAY_WOLTR
Sequence: MNLPTKIFFTSFIFGFILSPYFIKFLKKISKNGQPIRLCSPENHLITKRNTPTMGGVVILTSSLLPILFWVQSTPEILLLVSITLSFALIGFIDDYLKLKANSYRGLSAKTKILIQFIVALVGMSVFKLYFTEDFTKTFLFKGIMIDFSYLYAPFAAFIVVGSSNAVNLTDGLDGLAATQIIASFVSLGLVAYMTRADISVILFCITFIGATLSFLWFNTHPAKIFMGDIGSLSIGAALGLTSVLIKREVLFAVIGVIFVIETLSVVIQVLYFKYTRFKHGKGKRIFLMTPIHHHFEKKGWSENEIVIKFLIITIVCSVFTVAFLL
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LIPB_SHEHH
Sequence: MYDNALHIRHLGKQDYESVWHAMQHYTDNRDENSQDEIWIVEHTPVFTQGQAGKSEHILNPGDIPVIQVDRGGQVTYHGPGQLVVYPLLDIKRLKIGVRQLVTHIEQSIINMLKRYQIEAYAKADAPGVYVEERKIASLGLRIRKGCSFHGLALNVDMDMSPFQRINPCGYAGMEMIQCKQLGGPQTVEEAGRQLIETLSQELGLDKLVHHQGLPESYE
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YRR1_YEAST
Sequence: MKRRSDALLGSFQATNVTPPSDNSNSTAGGANGSNSGTPTSTSGKKRNKLIKSCGFCRRRKLRCDQQKPMCSTCISRNLTTCQYAEEFNKNIEKKATYGPYPNADLLKKVEELENKIRILEAEKNTNSSASSMYTSPNFPPLGTSVGRGSTETSSPLPDGVINPYADRYYLQSKHSGRSTLYGPTSMRTQIANSNWGFIEKYKQLWAKVKVERNKWKQNNQKTMCRELGLLDESDWQPDPLIKQICRFLPSYNKALSILDDFFNDGACNEINVILDKAKVRRDFLDYFMPEKEVKAEGDRSIVYILSNPKKNYYKAAVILLILCLKYFHTDVPTPIEKFFTLLKGASTAKVFYIERAQMLILFYYHRETYSFGGDGSDLVNINECLVTTVTTIGLHLNIRETFKEHEVFMGSIESLENVWLMAIFIDYNISCNVGRPLLINKFYLDENQDHCILNSKSKTYEGKLKRYLKLTRPMLLTLYDRDKFPDLKAYSKRIINFVEEELGPLGHYTGENISEEVPLRESRILSMAVGLLLSFYALIHSVLKVRNIESKNNTFQLVLINFSIIVNTTIRCYRIDKALYPEKFEASNPHLPPHMALSMSLTAGLFSKTLVFFCSLIYFKLTLFENGLCLSNDMEVGWSDLTKLTVPLDKDLSLGTAMSLYSSIFDRLFTVGNKELIRTMHRSSQFVIELAIERTYRTILGNVIEFRKLTEETWLAQIKQELDPQSDNPSSEAKIVSDRQRDLSLAVPTPTPSIIPMLPSPGETKNHAKSQSEIIQMLTDEFWANYNSGWEELINQSEFSTLFDDYKDN
What is the function of this protein?
Transcription factor involved in the regulation of multidrug resistance genes.  Acts in concert with YRR1.
What are the official names of this protein?
Zinc finger transcription factor YRR1, Pleiotropic drug-resistance protein 2.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CL060_MOUSE
Sequence: MSSESEKDKERLIQAAKLFFFHIRDLVSFINRFVELFNLTMKTQILPMNLNEESCIKDFFEQMIRNFKEMQLMVDGKHKQMQKEPLCSKVLTAMTSAVEKCATIAPHHTAEDMLRNIQTSGAALVLKTSHVLVNLETSLSLLMQFPIMGLRLSDLYREETKEQSDATSDATTSEKNKSPECPKATTEETLRKLQDVLSPENAHTPVEAAADELEQFVKSMEITLQVLQKSIKTMEGDIFVLTQVQGK
What are the official names of this protein?
Uncharacterized protein C12orf60 homolog.
Protein: EFG1P_PICST
Sequence: MPPKAAKGKRRPNGASIEVAGVLGGGASRLKKKIRDIERLLKKDKLPADVRTENERAVKALKVELQNTQFNLKAKQVAKKYHMVRFFEKKKAVRKLKQANKNLEDISKTDVRKDIKKARKQVKHCEIDLAYVIMFPKSEKYISLYPNPKENDEVDVSNPKAKKGMQMTEQRRREFRKEIEQLIENNRLPFTIGEVLQGKTVKIEFEGQNVAADHEIDAPEPKNNQQEEDDFFE
What is the function of this protein?
Involved in rRNA processing.
What are the official names of this protein?
rRNA-processing protein EFG1.
What is the protein family that this protein belongs to?
Belongs to the EFG1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ASP2_NECAM
Sequence: MRSILVLVALIGCIAAGVYKIPLKRITPPMIKMLRAGTWETYVEGMRKRQLQLLKEHKVHIQDVLGYANMEYLGEITIGTPQQKFLVVLDTGSSNLWVPDDSCYKEKRPDRCLVSNCDAGLVCQVFCPDPKCCEHTREFKQVNACKDKHRFDQKNSNTYVKTNKTWAIAYGTGDARGFFGRDTVRLGAEGKDQLVINDTWFGQAEHIAEFFSNTFLDGILGLAFQELSEGGVAPPIIRAIDLGLLDQPIFTVYFENVGDKEGVYGGVFTWGGLDPDHCEDEVTYEQLTEATYWQFRLKGVSSKNFSSTAGWEAISDTGTSLNGAPRGILRSIARQYNGQYVASQGLYVVDCSKNVTVDVTIGDRNYTMTAKNLVLEIQADICIMAFFEMDMFIGPAWILGDPFIREYCNIHDIEKKRIGFAAVKH
What is the function of this protein?
Aspartic protease which cleaves several human serum proteins including hemoglobin, fibrinogen and albumin.  Appears to cleave preferentially between P1 (Ala, Leu, Val, Phe and Gly) and P1' (Ala and Leu) residues.
What are the official names of this protein?
Aspartic protease 2, Na-APR-2, Necepsin I, Pepsin-like aspartic protease 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted into the gut lumen.
Protein: CCND1_RAT
Sequence: MEHQLLCCEVETIRRAYPDTNLLNDRVLRAMLKTEETCAPSVSYFKCVQREIVPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPLKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEADENKQIIRKHAQTFVALCATDVKFISNPPSMVAAGSVVAAMQGLNLGSPNNFLSCYRTTHFLSRVIKCDPDCLRACQEQIEALLESSLRQAQQNIDPKATEEEGEVEEEAGLACTPTDVRDVDI
What is the function of this protein?
Regulatory component of the cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition.  Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase.  Hypophosphorylates RB1 in early G(1) phase.  Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals.  Also a substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity.  Component of the ternary complex, cyclin D1/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.  Exhibits transcriptional corepressor activity with INSM1 on the NEUROD1 and INS promoters in a cell cycle-independent manner.
What are the official names of this protein?
G1/S-specific cyclin-D1.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin D subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Nucleus membrane. Note=Cyclin D-CDK4 complexes accumulate at the nuclear membrane and are then translocated into the nucleus through interaction with KIP/CIP family members.
Protein: RL33_ACIET
Sequence: MASKGGREKIKLVSTAETGHFYTTTKNKKTMPEKMSIIKFDPKARKHVEYKEAKLK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: ITB7_MOUSE
Sequence: MVDSSTVLIFLLVLGGGQSELDTKITSSGEAAEWEDPDLSLQGSCQPVPSCQKCILSHPSCAWCKQLNFTASGEAEARRCARREELLARGCPAQELEEPRGRQEVLQDKPLSQGDRGEGATQLAPQRIRVTLRPGEPQKFRVRFLRAAGYPVDLYYLMDLSYSMKDDLERVRQLGHALLVRLQEVTHSVRIGFGSFVDKTVLPFVSTVPSKLHHPCPSRLERCQPPFSFHHVLSLTGDAQAFEREVGRQNVSGNLDSPEGGFDAILQAALCQEQIGWRNVSRLLVFTSDDTFHTAGDGKLGGIFMPSDGRCHLDSNGVYTNSAEFDYPSVGQVAQALTAANIQPIFAVTGATLPVYQELRQLIPKSAVGELSEDSSNVVQLIMDAYDSLSSTVTLEHSPLPPGVSISFESHCKGPEKTEGEAGDRGQCNDVRVNQTVDFWVTLQATHCLPEAHVLRLWALGFSEELTVELHTVCDCNCGDAQPHAPYCSDGQGDLQCGICSCAPGRLGQLCECSEADLSSPDLESGCRAPNGTGPLCSGKGRCQCGRCSCSGQSSGRLCECDDASCERHEGILCGGFGHCQCGVCHCHANHTGRACECSKSVDSCVSPEGGLCSGHGYCKCNRCQCLDGYYGALCDQCLGCKSPCEQYRDCAECGAFGTGPLAANCSVVCADVNVTLTLAPNLDDGWCKERTIDNQLFFFLVEHAASGIVLRVRPQEKGVDHTRAIILGCTGGIVAVGLGLVLAYRLSVEIYDRREYRRFEKEQQQLNWKQDNNPLYKSAITTTVNPRFQGTNGRSPSLSLTREAD
What is the function of this protein?
Integrin alpha-4/beta-7 (Peyer patches-specific homing receptor LPAM-1) is involved in adhesive interactions of leukocytes.  It is a receptor for fibronectin and recognizes one or more domains within the alternatively spliced CS-1 region of fibronectin.  Integrin alpha-4/beta-7 is also a receptor for MADCAM1 and VCAM1.  It recognizes the sequence L-D-T in MADCAM1.  Integrin alpha-E/beta-7 is a receptor for E-cadherin.
What are the official names of this protein?
Integrin beta-7, Integrin beta-P, M290 IEL antigen.
What is the protein family that this protein belongs to?
Belongs to the integrin beta chain family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RS8_BUCAI
Sequence: MSMQDPVADMLTRIRNGQLANKYSVKMPSSKLKKSIIQLLKEEGYIKDYNVTGDTKLELEVFLKYFQGKSVVDMIQRISRPSLRIYKNKNNLPKVMSGLGIAVISTSKGVMTDRMARQEGLGGEVICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: H7_RABPU
Sequence: MEMDKRMKSLAMTAFFGELSTLDIMALIMSIFKRHPNNTIFSVDKDGQFMIDFEYDNYKASQYLDLTLTPIFGDECKTHASSIAEQLACADIIKEDISEYIKTTPRLKRFIKKYRNRSDTRISRDTEKLKIALAKGIDYEYIKDAC
What is the function of this protein?
Contributes to the formation of crescents and immature virions (IV).
What are the official names of this protein?
Late protein H7 homolog.
What is the protein family that this protein belongs to?
Belongs to the chordopoxvirinae H7 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Note=Probably transitorily part of the membrane of crescents during immature virions formation. Not incorporated into virions. Probably synthesized, but not retained in viral factories (By similarity).
Protein: RL1_STAHJ
Sequence: MAKKGKKYQEAANKVDRTKHYSVEEAISLAKETSIANFDASVEVAFRLGIDTRKNDQQIRGAVVLPNGTGKSQRVLVFAKGDKITEAEEAGADYVGESEYVQKIQQGWFDFDVVVATPDMMGEVGKLGRVLGPKGLMPNPKTGTVTMDVKKAVEEIKAGKVEYRAEKAGIVHASIGKVSFSDEKLVENFKTLQDVLAKAKPSSAKGTYFKSVAVTTTMGPGVKIDTSSFKL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: ABCC5_DICDI
Sequence: MKYNNLENDDSDIHNNNNNNESEGDSLIELEEINLEGNNNNDINNNNNINNNNDSLDYENNKGSKKKNNKKYVILNEEEDINDKKVENGENETSSFTYGHDNEFKDLPLPKKGFGGLKSLEENANFLSSMTYLWADKFVLYCFKNILQLDEIWELASYDKSSYLFDIMDKNWQNELKNSKKPNFMKAAFKSFGKHFALSWVHFGLNVISQFIGPIFLKKIVSFVIQYRENPGSVDPNLGYYYALILFVNSMLGSIFLYQSNMITSRTGNRLKSLIVLYVYKKSLKLTNSSRSKKSNGEIVNLMSNDAQRLLELFQMVNTLIFAVPMIIVSMILLYDCVGWPSFVALLVMGISLPYSLNRGSQLSIYRRKLVGFTDQRIKVVNEMFQAIKTIKLYAWEDYFSQKMMSKRGEEIKFLTQFVRFRYSLIVVVQSIPTIISIFMFTVYYLVNSKLPADKIFAAVAYLNIIRVPFTFLPYGYNIYIQFKVSIERVVNFLNMDEINQGDDKNNEINVNVCDQQKQQQTDIGIYMDNTTFSWAIKPQTNPPPPRTTPSNDKSSPSGNNSNNEKKEVQVSFSLKNTSCQVKEKGSLLMVIGPVGSGKSSFCQALLGEMELENNGSLRVVGSIAYVSQSAWIMNASLKDNILFGKEYNKERYEMVLNCCALLPDLALFPQGDLIEIGERGINLSGGQKQRVAIARAVYSDSDIYILDDILSAVDAHVGKHLFYNCIKGILKEKIVVLATNQLNYCPYSTQTLILKTGGEVEQYDTFENIISTINSAYGNSSLFSELLKQYAHMAGDSDKDSDEIVDDEMIKSKENNNDLYDGKLTTIEEREEGSVSFKHYMYYVTAGGGFLFLIALLGYCIDTSTSTFTNWWLSNWSSKHTSTGINNNNSSSSNSISSSSSYIIDSLSSLNINEDGDIENAGEFLGVFIAIGVLTVLLIIVRTIVFFEYSIRATTEIHKRLFWSILRAPMWFFDTVPLGRILNRFTRDTDIVDMLLTNSLNQFLNFSTNCIAILVIISIATPWLLLPMTPIIILFYFIQYFYRRTSIQIQRIESITRSPIFSHFAETLNGVITLRAFRKMGENVLKNQALLDDNNKCYLTLQAMNQWLGLRLSVLGNLITLLSCIFITVDRSSIAIASVGLSISYTLSLTTNLNKATQQLAELETKMNSIERISYYTENVPQEPDQIIESNRPPMGWPSLTNSNHTPPIIFENVVMSYRQGLPAVLKGISFEIKAGEKIGICGRTGSGKSSLLLALFRIVELSSGRIIIDGLDISKIGLKDLRSQLAIIPQEPVMFTGTLRSNLDSLSEHTDSELWDVLKEIQLYEHVKKVSVADEGLDLRVNDNWSQGQKQLIGLGRALLKKPKILVCDEATASVDSLSDELIQRIIREKFKDAIILTIAHRLNTIVESDRIMVLDSGSIVEFNKPSILAQNENSLFNWLIDETGTQNSQYLRSLIKH
What are the official names of this protein?
ABC transporter C family member 5, ABC transporter ABCC.5.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: APAH_XANOR
Sequence: MSVWAIGDLQGCYDITQRLLEKINFDPAQDTLWFCGDLVNRGGQSLETLRLVHSLRAHSVVVLGNHDLSLLAIGARSEEEQRKVNPDLLRIVLAEDRDALLDWLRMQKLAHVDRALGWMMIHAGLAPKWTTQMAEKHAREVEQQLQGGGYRKLLRNMYGDQPGWSPGLIGYDRSRAIINLFTRMRYCTPRGRIATDDKGTPGTQAQGLYPWFEVPGRVERDLKIVCGHWSALGLTITQGVHAIDTGAVWGGKLTALQLDTDELRVVQVPGREVTGPAPVARAPRRPRERLGRQRSRGNRGNAGNTAVPAKPQVDTPQD
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: Y1552_METJA
Sequence: MGIKYLLRDKMVVRSWRHIKERYCLIGVRCKNCGTVYFPSREICPKCRRKTEFEEIKLSGKGKVYTYSVVHVAPKDFEKQAPYVIAIIELEEGARITGQIVDCKPEDVYIGMQVEAVFRRIKEDGDDGVITYGYKFKPIEN
What are the official names of this protein?
Uncharacterized protein MJ1552.
Protein: RS12_GLAP5
Sequence: MATINQLVRKPRVKKVVKSNVPALEACPQKRGVCTRVYTTTPKKPNSALRKVCRIRLTNGFEVTSYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHTVRGALDCAGVKDRKQGRSKYGVKRPKS
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: LEUC1_METKA
Sequence: MGKTMAEKILSRASGEDAEAGDIVVANIDVAMVHDITGPITVQRLEEMGVERVWDPSKIVVLFDHQVPADSVEAAENHKIMREFVEEQGIEHFYDVREGVCHQVLPEKGHVRPGDVIVGADSHTCTHGALGAFATGIGSTDMAAVFATGKLWFRVPETYRVEITGELPEGVYAKDVVLKVTGEIGADGATYMAIEYHGEVVREMSVSDRMCLCNMAIEMGAKTGMVPPDEKTLEYVKKRAGTEGRPVEPDPDARYEAELTLDVSDLEPQVAKPFSPDNVVPVGEVEGIAIDQVFIGSCTNGRYEDLKVAAEVLEGEEVHDDVRLIVIPASREVYHRTLKDGVLEVLHEAGALICPPNCGPCLGGHMGVLAEGERCVATSNRNFPGRMGHRESEVYLASPATAAASAIEGEITDPRPYL
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit 1, Alpha-IPM isomerase 1, IPMI 1, Isopropylmalate isomerase 1.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
Protein: Y1103_ORYSJ
Sequence: MAGQAPNMLAPPTDDELLHAQADLWRHSLYFVTSMAFQCAVKLGIPTAIHRAGGTASLPDLVAALSLPPAKLPFLRRLMRLLVHSGVFAAADDTTGSAGTYRLTPLSWLLVEGEGGAPVVDGHPCQVPVVLAGTSRHFVEAAMGLAEWFRKDVPAAAPPSPFEEVHGAVLFDESMASLHPEVDTVFNQALAAYDHSGFATVLRECSEVFQGVQSLTDCRGGDGAAAKAIVEAFPHIKCTVLDFPRVIGNKRGDGVVNYVAGDMFRAIPPAQAVMLKLVLHHWSDEDCVKILTQCKKAIPARKDGGKVIIIDIVIGAPSGPLLEAQLLMDVGMMVATKGRQRDENDWRDLFKKAGFNNYKIVKKLRARAVFEVYP
What are the official names of this protein?
Flavonoid O-methyltransferase-like protein Os11g0303600.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. COMT subfamily.
Protein: HBA_AEGMO
Sequence: MVLSANDKTNVKTVFTKITGHAEDYGAETLERMFITYPPTKTYFPHFDLHHGSAQIKAHGKKVVGALIEAVNHIDDIAGALSKLSDLHAQKLRVDPVNFKLLGQCFLVVVAIHHPSVLTPEVHASLDKFLCAVGNVLTAKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-A, Alpha-A-globin, Hemoglobin alpha-A chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: GLYA_BEII9
Sequence: MNAKVEVGQPAANSFFAANLADADPEIAKAIELELGRQRHEIELIASENIVSKAVLEAQGSIMTNKYAEGYPGKRYYGGCQFVDIAENLAIERVRKLFDCQFANVQPNSGSQANQAVFLALLQPGDVFMGLDLAAGGHLTHGSPVNLSGKWFKAVSYGVRQSDHLIDMDAVEALAKEHKPKLIIAGGSAYPRHWDFARFRAIADSVGAYFFVDMAHFAGLVAGGAHPSPFPHAHVVTSTTHKTLRGPRGGLVLTNDADIAKKINSAVFPGLQGGPLMHVIAAKAVAFGEALRPDFRLYAQQVVVNAGTLASRLVEKGFAISSGGTDNHLMLVDLRPKQLTGKAAEAALGRASITCNKNGVPFDTASPFVTSGIRLGSPAATSRGFGTKEFQDVADLIAETLDGLAKNGEEGNAAVEASVKERAIALTQRFPIY
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNN_ALIFM
Sequence: MKIGIIGAMEQEVAILKDKIEGLSTVTKAGCTFYTGTLNGADVVLLQSGIGKVAAAVGTTLLIAEHNVDVVLNTGSAGGFDSSLNLGDVVISTEVRHHDADVTAFGYEMGQMAQQPAAFIADEKLITTAEQALTEMSDKHAVRGLICTGDVFVCTPERQEFIRTHFPSVIAVEMEASAIAQTCHQFNTPFVVVRAISDVADKESPMSFDEFLPLAAQSSSEMVLNMVTLLK
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: SYFA_AGRFC
Sequence: MTELDTLKSQLMSEIAAAADEPAIEAVRVSALGKKGSVSELLKTLGSMTPEERQTRGAAINQLKTEITDLIGERKNALKDAAIAARLKAETVDVSLPVRQSPTERGRIHPISQIVDEITAIFADMGFSIAEGPDIETDYYNFTALNFPEGHPAREMHDTFFFQPDEKGERKVLRTHTSPVQIRTMESQKPPIRIVIPGKTYRQDSDATHSPMFHQVEGLVIDKKAHVGNLRWVLEEFCKTFFEVDSVVMRFRPSFFPFTEPSFEVDIQCDRSGPIVKFGEGKDWMEILGCGMVHPNVLRAGGLDPDEYQGFAWGMGLDRIAMLKYGMPDLRDFFNADVRWMNHYGFRPLDMPTLFGGLSV
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KHSE_STRCO
Sequence: MAGPAFRAAAVRVRVPATSANLGPGFDALGLALGLYDDVVVRVADSGLHIDIAGEGSETLPRDEKHLLVRSLRTAFDLLGGQPRGLEIVCANRIPHGRGLGSSSAAICAGIVAARAVTIGGEARLDDAALLDLATEIEGHPDNVAACLLGGFTLSWMESGAARAIRMEPSDSIVPVVFVPGKPVLTQTARGLLPRSVPHVDAAANAGRAALLVEALTRRPELLLPATEDRLHQEYRAPAMPESTALVERLRGDGIPAVISGAGPTVMALADADTADKVEALAGTDWAANRLGLDQQGATVLPLATASDT
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FCN2_PIG
Sequence: MDTRGVAAAMRPLVLLVAFLCTAAPALDTCPEVKVVGLEGSDKLSILRGCPGLPGAAGPKGEAGASGPKGGQGPPGAPGEPGPPGPKGDRGEKGEPGPKGESWETEQCLTGPRTCKELLTRGHILSGWHTIYLPDCQPLTVLCDMDTDGGGWTVFQRRSDGSVDFYRDWAAYKRGFGSQLGEFWLGNDHIHALTAQGTNELRVDLVDFEGNHQFAKYRSFQVADEAEKYMLVLGAFVEGNAGDSLTSHNNSLFTTKDQDNDQYASNCAVLYQGAWWYNSCHVSNLNGRYLGGSHGSFANGVNWSSGKGYNYSYKVSEMKFRAT
What is the function of this protein?
May function in innate immunity through activation of the lectin complement pathway.  Calcium-dependent and GlcNAc-binding lectin (By similarity).
What are the official names of this protein?
Ficolin-2, Collagen/fibrinogen domain-containing protein 2, Ficolin-B, Ficolin-beta, L-ficolin.
What is the protein family that this protein belongs to?
Belongs to the ficolin lectin family.
What are the subcellular locations of this protein?
Secreted.