PharMolix/UniProtQA huggingface dataset:
Protein: RUVC_PSET1
Sequence: MAIILGIDPGSRLTGYGVVAHQGSKFTYLGSGCIKLADHEFHIRLKMIYQGITQLIEQFSPETFAIEKVFMAHNPDSALKLGQARGAAIVGAAMADLPVFEYSARQIKQAVVGNGGADKTQVQHMVKNILKLPGTPQADAADALAIAICHAHSEQNLIKLAGSASKTVRGRLRK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: NRDI_ECOSM
Sequence: MSQLVYFSSSSENTQRFIERLGLPAVRIPLNERERIQVDEPYILIVPSYGGGGTAGAVPRQVIRFLNDEHNRALLRGVIASGNRNFGEAYGRAGDVIARKCGVPWLYRFELMGTQSDIENVRKGVTEFWQRQPQNA
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: RL7_MYCCT
Sequence: MPITKDEIIKALEEMKLNELNELVKAIEDHFGVVASVGVAAAAPAEATNAAPTEVSVVMTSVGQQKVAVIKVVKELTGVGLMDAKKMVDGAMPVTIKEHVKPEEAEEMKAKLVEAGASIDLK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: CSRA_LEIXX
Sequence: MLVLTRKQGEKILIGDDIEITVLDTRGDGIRIGISAPRGIRIQRDEVRKAIEAENRSAAMRNPAAEFELIASLTALQNAEDPPPR
What is the function of this protein?
A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation.  Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
What are the official names of this protein?
Translational regulator CsrA.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATC_DICT6
Sequence: MERRDFKEQLKKTAHLARLHLTPEEEELFAKQLQNILDYFKKLQELDTSNVEPMAHVLPLYNIWREDEVRESISQEEALKNAPEIEDLGFKIPRIMKREE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: PSAA_STAPU
Sequence: MTIRSPEPEVKIVVDNDPVKTSFEKWAKPGHFSRALAKGPSTTTWIWDLHADAHDFDSHTSDLEEISRKVFSAHFGQLAVIFIWLSGMYFHGARFSNYEAWLSDPVNIKPSAQVVWPIVGQEILNGDVGGGFQGIQITSGLFEMWRGSGITTELQLYSTAIGGLVMAALMLFAGWFHYHKAAPKLAWFQNVESMLNHHLAGLLGLGSLGWAGHQVHVSLPINQLLDAGVDAKEIPLPHEFILNRDLLAQLYPSFAKGLTPFFTLNWAEYSDFLTFRGGLNPVTGGLWLTDTIHHHLAIAVLFIVAGHMYRTNWGIGHSMKEILEAHKGPLTGEGHKGLYEIFTTSWHAQLALNLALMGSLSIIVAHHMYSMPPYPYLATDYGTQLSLFTHHTWIGGFCIVGAGAHAAIYLVRDYDPTTQYNNLLDRVLRHRDAIISHLNWVCIFLGFHSFGLYIHNDTMSALGRPQDMFSDTAIQLQPVFAQWVQNTHAAAPGFSAPNAAAATSITWGGSELVAVGGKVAMSPIPLGTADFLVHHIHAFTIHVTVLILLKGVLFARSSRLIPDKANLGFRFPCDGPGRGGTCQVSAWDHVFLGLFWMYNSISVVIFHFSWKMQSDVWGTVSQNGVSHITGGNFAQGATTINGWLRDFLWAQASQVIQSYGSSLSAYGLVFLGAHFVWAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPAIQPRALSIIQGRAVGVAHYLLGGIATTWAFFLARIISVG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PSI-A, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: NOC4L_MOUSE
Sequence: MERHPASASSRQELGRLLEAVLTSRGQANAVFDILAVLQSEEPEEIEEGVRTCSRLFGTLLEREELFVGSLPSEDTALAGSQGATYKYKVWIRHRYHSCCNRLEELLAHPTFQVKELALKTLMKFVQLEGAKPLEKPQWESHYLFPRTLFRAVVGGLLTPEDDHSLLISHFCEYLEYDDIRYHTMQVATSIMARATSQQPEVSLTLWNNAFTLLSAVSLPLQECELTNFYVKHAQTSDKWKVVHLKEHKKAFQEMWLGFLKHKLPLSLYKKVLVAMHDSILPHLAQPTLMIDFLTSACDVGGAISLLALNGLFILIHKHNLEYPDFYQKLYGLLDPSIFHVKYRARFFHLADLFLSSSHLPAYLVAAFAKRLARLALTAPPEALLMVLPLICNLLRRHPACRVMVHRPQGPELDADPYDPTEKDPARSRALESCLWELQTLQQHYHPEVSKAASVINQVLSVPEVSIAPLLELTAYEIFEQDLKKKMPESVPLEFIPAKGLLGRQDDLCTQFFCLS
What are the official names of this protein?
Nucleolar complex protein 4 homolog, NOC4 protein homolog, NOC4-like protein, Nucleolar complex-associated protein 4-like protein.
What is the protein family that this protein belongs to?
Belongs to the CBF/MAK21 family.
What are the subcellular locations of this protein?
Nucleus membrane; Multi-pass membrane protein. Nucleus, nucleolus.
Protein: PYRB_RHIME
Sequence: MITFPHRHLLGIKGLTEQDITLLLDRADEAVKISRQREKKTSSLRGLTQINLFFEASTRTQSSFELAGKRLGADVMNMSVGNSSVKKGETLIDTAMTLNAMHPDVLVVRHSSAGAASLLAQKVSCSVVNAGDGQHEHPTQALLDALTIRRAKGKLSRIIVAICGDVLHSRVARSNILLLNQMGARVRVVAPATLLPAGIAEMGAEVYHSMAEGLKDADVVMMLRLQRERMAGSFVPSVREYFHYYGLDAEKLKVAKDDALVMHPGPMNRGVEIASEIADGPQSVIEQQVEMGVAVRMAVMETLLLSQNQGPRL
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: Y2941_VIBC1
Sequence: MSKQVGLIHSLKDGQSYMEIWPVRKELNAIFPEQRIIKATRFGIKVMPAVAAISVLTQMAFNNYDSLPQAIVVALFAISMPLQGMWWLGSRSNTKLPPALASWYRELHQKITETGFALEPVKARPRYKELAVILNRAFRQLDKTALERWF
What are the official names of this protein?
UPF0208 membrane protein VIBHAR_02941.
What is the protein family that this protein belongs to?
Belongs to the UPF0208 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DAPF_AZOVD
Sequence: MLLRFTKMHGLGNDFMVIDLVTQHAHIQPKHAKQWGDRHTGIGFDQLLIVEPPSRPDVDFRYRIFNADGSEVEQCGNGARCFARFVLDKRLTVKKRIRVETRSGVIELDVRPDGQVCVDMGPPRLEPREIPFQAENAALDYQVEVDGCEVELAALSMGNPHAVLRVENVESAPVHELGPKLEHHPRFPQRVNVGFLQVVDRQHARLRVWERGAGETQACGTGACAAAVAAIRQGWMDSPVLVDLPGGRLSIAWAGPDQSVMMTGPAVRVYEGQVRL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YEEB_BACSU
Sequence: MENIIEINYNQTGKSKKTNEYGMREMQARAFEKRNSQYLLVKAPPASGKSRALMFIGLDKLINQGLRKVIVAVPERSIGSSFKNTDLKSYGFFENWKVDPRNNLTVGGDNSKVKSFVRFMESDDQVLICTHSTLRFAFEKIDDKAFDNCLLAIDEFHHVSADVNSRLGELLRSIIHNSSAHIVAMTGSYFRGDSVPILLPEDEELFDKVTYSYYEQLDGYEYLKGFGIGYHFYQGQYTSAINEVLDTNKKTIVHIPNVNSGESTKDKYDEVGKILDMIGEVEYQDDDTGIIYVKRHSDGKTLKIADLVDDQVGRENVVAYLRNIEALDDLDIIIALGMAKEGFDWPFCEHTLTVGYRGSLTEIVQIIGRCTRDSYNKTYAQFTNLIAMPDAKDEVVTYTVNTMLKAISASLLMEQVLTPDFKFKRRRNESEKSSTTGELFVKGLKEPSTENVKKIIENDINDLKAKIMQDSQVQKTFSGEVDPKVLNKVLIPKVIQKVYPNLSDEEIEEVRQHVVLDTVMKGAKSEVVGSKEFIRMADKFINIEDLDINLIDSINPFQKAFEVLSKELNSPVLKLIQETIDAKRINFDEDELVFIWPKV
What are the official names of this protein?
Putative ATP-dependent helicase YeeB.
What is the protein family that this protein belongs to?
Belongs to the helicase family.
Protein: LEUC_BACTN
Sequence: MNTLFDKIWDAHVVTTVEDGPTQLYIDRLYCHEVTSPQAFAGLRERGIKVLRPEKVFCMPDHNTPTHDQDKPIEDPISKTQVDTLTKNAKDFGLTHFGMMHPKNGIIHVVGPERALTLPGMTIVCGDSHTSTHGAMGAIAFGIGTSEVEMVLASQCILQSRPKTMRITVDGELGKGVTAKDVALYMMSKMTTSGATGYFVEYAGSAIRNLTMEGRLTLCNLSIEMGARGGMVAPDEVTFEYIKGRENAPQGEAWDQAMEYWKTLKSDDDAVFDQEVRFDAADIEPMITYGTNPGMGMGITQNIPTTEGMGEAAQVSFKKSMEYMGFQPGESLLGKKIDYVFLGACTNGRIEDFRAFASLVKGRRKADNVIAWLVPGSWMVDAQIRKEGIDKILTEAGFAIRQPGCSACLAMNDDKIPAGKYSVSTSNRNFEGRQGPGARTLLASPLVAAAAAVTGVITDPRELM
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: PSAC_SOLTU
Sequence: MSHSVKIYDTCIGCTQCVRACPTDVLEMIPWDGCKAKQIASAPRTEDCVGCKRCESACPTDFLSVRVYLWHETTRSMGLAY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: RS7_AGRRK
Sequence: MSRRHRAEKREINPDPKFGDLIVTKFMNAIMLDGKKSVAESIVYGAFDAVQGKAKQEPLGVFHQALDNIAPHVEVRSRRVGGATYQVPVDVRPERRQALAIRWLITAARKRNETTMVDRLCGELLDASNNRGSAVKKREDTHKMADANRAFSHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: SOBPA_DANRE
Sequence: MAEMEKEGRPPESKRSRKPAHPVKREINAEMKVPSNRPLPGAGQAGNLHGNSPYLMSFAENTMNELLGWYGYDKVELRDSDDIEIRNYPDGEMRQHISVLKENSLPKASTLENSSGSPPHANSSGSTPTSRNGVTAESSVNPSSSKEHGGLPIIVPLIPPPLIKAPAEEDSSNVQIMCAWCQKVGVKRYSLSMGSELKSFCSEKCFAACRRAYFKRNKLGYVRNCSAREEEGVPTHSLSKDTPRLVLKTNSDVLVCDWCKHIRHTKEYLDFGAGERRLQFCSAKCLNQYKMDIFYKETQAALPGGLCNPPLPTSDTKSESGAGVQLLTPESWSAPLSELRSRKAPSPVGATIAGPSGSTSGSPSEAGTVCSSSSSSSSSSSSTKIPTPRPHESPSLPPPHPPPISGLHPALGMPPGSPPMVMTPRGPVPFPIFMEHQMMQQMRPPFLRPPGPNSPHSNPMIPGIGPPPPPRTLCPPSSPMHRPLLSPHLHPSSTPTLSGNPPGIMPPHPAAHMPGLPFPPVNMMPSGPIPVPPIMNIGMPSLAPLVPPPTLLVPYPVIVPLPVPIPIPVPIPYNPQRSGDRPGNDGTLPNTANEQKDSKAPPSFSSRGEERDFQKAPPNSDTLSPEFSKQTEQGRTNMADLMVKMENSGKGSSEHSHKDTPADGVIDLTTSHRSRQQLVIQRAVTCVQVKAEPGLSPPPALLGETELDGSTSISTGTAKDDHRDTYSNAESPLASVALPCADPSYCSGTPPLSQPITCSASIIPSNITTAKTEPGSATPCNVIVNGSCNLPPTESLIRTPPLEQRPQVDTCRRTATVCDEPAGADLEGEDLKENSCLATEKDSAGKRCSNDQSAITTGTGDDKSQSPEDDPSGEDHAYALPLMPKPGCVIQPVPKPAEKTAAILPCGLTAPLTGTVPMEMEPPLKRRCLRIRNQNK
What is the function of this protein?
Implicated in development of the cochlea.
What are the official names of this protein?
Sine oculis-binding protein homolog A, Jackson circler protein 1A.
What is the protein family that this protein belongs to?
Belongs to the SOBP family.
Protein: RS27A_SCHPO
Sequence: MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGGKKRKKKTYTTPKKIKHKHKKVELAVLKYYKVEDDGSVKRLRRECPNCGASTFMANHKDRLYCGRCHLTLKLEN
What is the function of this protein?
Ribosomal protein S27a is a component of the 40S subunit of the ribosome.
What are the official names of this protein?
Ubiquitin-40S ribosomal protein S27a.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
What are the subcellular locations of this protein?
[Ubiquitin]: Cytoplasm. Nucleus.
Protein: RL30_VESOH
Sequence: MAKENRTVKKVTTIQKTQVSSKHNTVSVTLVKSFHGRLPSHRETIVGLGLKRINHTKKFKDTSEIRGMINKVSYLLKVEN
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: SYFA_KARMG
Sequence: MLNKIKNINKELDIININSASELEFFRIKFLGKKGILNSLFKEFKKIDSNEKRNIGLSLNILKIKIKNLILKFKFLKKKKIDDLEIDDLTKPGKKKNLGSRHPISIIKHRIINIFNKIGFKICEGPEIEYDWYNFTALNFPYYHPAREMQDTFFIKKSNKLLRTHTSSVQIRYMEKNKPPIRIISPGRVYRNEKISAYSHCMFHQIEGLYLDKKVSFKDLKSTINFFIKNFFGKSITRFRPSYFPFTEPSAELDILWNNKWLEIIGCGMVDPIVLKNVNIDPDLYSGFAFGMGIERITLMIYKINDIRYFFENDLRFLKQFKKEF
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
Protein: SRP68_CAEEL
Sequence: MTNDVEMKSETEELPPFPTVHILQVVKDAQQQHGLRHGDYARYRKYCAAKLERMRKALKFTNSHNCQKKRKAKFVKKWLSVESVQNVQFLNFGIFESERRYAEAMIDKITLEDNPEKSRKKFSMINSLRKAVLHATNLEKIVQESERFDAPTKLEAQAYAAWMRGMCSFESRNWQKASESLKLAKTVYEKLAEATNNTTLSSIFKGRCREIQPQLRLCEFNIAESPGAVGTMTELMELRMQMGEGGDSSVDKLISEMRASATSAEVVTIEWGGAKSTVDDEKAKQVVQEWKQTEVELAQCQTPKEKMALFEKATADTRDAIDRISDIIRRKSSENADTTVLQSIKAYLEFLKMNGTASRYLAIIDNTKSEKKSKPQDLLRLYDSVIEIYKEVAEIPGADHDKNLIQAFEVKVEYYRAFRCFYMASSYSALHKYSEAAALFDRTVSRVQDAEGKLKKLKSSSFITNETQSSLNELRSEVESAKVTVRAARLASAAGDVKTDSELAKIIDKRPLLETVNEWRQWDVRNSLKDKKTIPVASLPPAFIPMPNKPIFFDLANFHLTMPNVDDRLEKLQKDRDATPKKAAKGSSAAAASSKTSNQEEEEQQGLTGMLSGWKKSFWGNK
What is the function of this protein?
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (By similarity).  The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER (By similarity).  The SRP complex targets the ribosome-nascent chain complex to the SRP receptor (SR), which is anchored in the ER, where SR compaction and GTPase rearrangement drive cotranslational protein translocation into the ER (By similarity).  Binds the signal recognition particle RNA (7SL RNA), srpa-72 binds to this complex subsequently (By similarity).  The SRP complex possibly participates in the elongation arrest function (By similarity).
What are the official names of this protein?
Signal recognition particle subunit SRP68, SRP68, Probable signal recognition particle 68 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the SRP68 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Endoplasmic reticulum.
Protein: RFC1_SCHPO
Sequence: MSNSDIRSFFGGGNAQKKPKVSPTPTSPKPKRSLKKKRIVLSDDEDGTIENSKVPASKSKVQKRNESEDISHSLPSIVHEDDKLVGSDGVSTTPDEYFEQQSTRSRSKPRIISNKETTTSKDVVHPVKTENFANDLDTTSDSKPVVHQTRATRKPAQPKAEKSTTSKSKSHTTTATTHTSRSSKSKGLPRFSDEVSQALKNVPLIDVDSMGVMAPGTFYERAATTQTPGSKPVPEGNSDCLSGISFVITGILETLTRQEATDLIKQYGGKVTGAPSVRTDFILLGENAGPRKVETIKQHKIPAINEDGLFYLITHLPASGGTGAAAQAAQQKKEQEEKKILETVARMDDSNKKESQPSQIWTSKYAPTSLKDICGNKGVVQKLQKWLQDYHKNRKSNFNKPGPDGLGLYKAVLLSGPPGIGKTTAAHLVAKLEGYDVLELNASDTRSKRLLDEQLFGVTDSQSLAGYFGTKANPVDMAKSRLVLIMDEIDGMSSGDRGGVGQLNMIIKKSMIPIICICNDRAHPKLRPLDRTTFDLRFRRPDANSMRSRIMSIAYREGLKLSPQAVDQLVQGTQSDMRQIINLLSTYKLSCSEMTPQNSQAVIKNSEKHIVMKPWDICSRYLHGGMFHPSSKSTINDKLELYFNDHEFSYLMVQENYLNTTPDRIRQEPPKMSHLKHLELISSAANSFSDSDLVDSMIHGPQQHWSLMPTHALMSCVRPASFVAGSGSRQIRFTNWLGNNSKTNKLYRMLREIQVHMRLKVSANKLDLRQHYIPILYESLPVKLSTGHSDVVPEIIELMDEYYLNREDFDSITELVLPADAGEKLMKTIPTAAKSAFTRKYNSSSHPIAFFGSSDVLPMKGSAQREVPDVEDAIEAEDEMLEEASDSEAANEEDIDLSKDKFISVPKKPKKRTKAKAEASSSSSTSRRSRKKTA
What is the function of this protein?
The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins PCNA and activator 1.  Subunit 1 is essential for cell cycle progression.  It may associate with components of the DNA replication machinery and serve to enhance the efficiency of DNA replication.
What are the official names of this protein?
Replication factor C subunit 1, Replication factor C1.
What is the protein family that this protein belongs to?
Belongs to the activator 1 large subunit family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RS4_PSYWF
Sequence: MARYIGPKLKLSRREGTDLQLKSGVKPYDVKTKKAGRVPGQHGNTRNKASEYSLQLREKQKVKRMYGVLERQFANYYKESARARGATGEHLLQMLERRLDNVVYRMGFGSTRAEARQLVSHRAVMIKKAGRDEFVRVNIPSIQVQDGDVIAIHEKAKEQLRIKNAIELATQRGIPEWLEVDHSKMQGTFKQAPDRIDLPAEITESLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: IF2_MALP2
Sequence: MEVFMAKNVKTKSKNKNKKIVDNRTNIDIKSQFKKVETGIKNGVFVFTNNLTIDEFSKKINKHSAEIIKYLFLKGINCNLNTLLDERQMGELCLEFGYDFKKEIQINEDNFLDNIKFEDREDLLDKRPPIVTIMGHVDHGKTTLLDTIRKSKVAATEAGNITQSIGAYQVEWKKHLITFFDTPGHEAFSKMRAVGADLTDIVVLVVAADDGLKPQTEEAIDHALFAKAPIIVFINKMDKKDANIEKIYSQLAEKNVLCEEWGGKTMVIKGSALNNQGIDELLEAIIVTAEIMELKANPKRLANGITIEASMDKGEGAVADLLVQSGTLAVNDYILVGEYYGKVKKMVDFNRKEIKTALPSTPVRISGLNGIPKSGDKWIVTNDEKLLKELSEKRQLNTKQRKLSNFGTNLNENSQGIKELNVILKTDNNGSLEAIKGLLSSIEVTGAKLNLVRAAIGSINESDIDLARTSKSLVVIFNTKVSSKVSDYAISMGITIKNYNIIYQIKDEIERLLKGILDPVFVEKEIGSVEIRQLWSHSSIGVIAGGRVLTGEIKRNAFARIKRKDKEIISNAKINSLRHGKDSIASAAAGKECGFTLENFNDFVEGDIVEIYEIVGETHE
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_RENSM
Sequence: MSRIGRLPISVPAGVEVKVDGALVSVKGPKGQLTLTVSNPIEVALEESTLTVSRPNDERASRSLHGLTRTLIANLITGVTEGYEKKLEIVGTGYRVLAKGSDLEFALGYSHPVAVKAPEGITLTVEGPTKLSVAGIDKQQVGEVAANIRKLRKPDPYKGKGIRYADEVIRRKVGKAGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: CAPSD_OUMVV
Sequence: MARLPKRKNRRNEKKKNANASRVQNVPRTFGLWKSTERIKYTTELKYLNSKCRAIRLHPDLVANNSFPTYCSAWKIDQVEFEFVSYMSPLAGHVGCVFFVVIPAKGLNSRISADEAESLQSAILWDEKGRLKITPISGPISRHPWTNLSQVVTPPQIPKGSTDGERQDLQSGYYLIFDSRKLFGKDLVDKQSVLGELSLTITATYWTSLS
What is the function of this protein?
Capsid protein self-assembles to form a baciliform capsid with a T=1 symmetry, about 18 nm in diameter.  The capsid encapsulates three genomic RNAs (Potential).
What are the official names of this protein?
Capsid protein, CP, Coat protein.
What are the subcellular locations of this protein?
Virion.
Protein: FPR1_MACMU
Sequence: NSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMRHTVTTISYLNLAVADFCFTSTLPFLMVVKVMRGHWPFGWFLCKFIFTIVDINLFGSVFLIALIALDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFDFSPWTNDPVEKLKVTIAMLTVRGIIRFIIGFSVPMSIVAVSYGLIATKIHKQGLIKSSRPLRVLSFVVAAFFLCWSPYQVVAFIATVRLRNILQGLSKELRIAVDATSALAFFNSCLNPMLYVFMGQDFRERLIHSLPTSLERALTEDSAQTSDTATNSTLPSAEVPLQA
What is the function of this protein?
High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors.  Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release.  This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system (By similarity).  Receptor for TAFA4, mediates its effects on chemoattracting macrophages, promoting phagocytosis and increasing ROS release (By similarity).  Receptor for cathepsin CTSG, leading to increased phagocyte chemotaxis (By similarity).
What are the official names of this protein?
fMet-Leu-Phe receptor, fMLP receptor, N-formyl peptide receptor, FPR, N-formylpeptide chemoattractant receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Internalizes in presence of its ligand, TAFA4.
Protein: MJK2_METJA
Sequence: METSKKLVIVAVLSITLILTYAYLISIIEGVDYFTALYFSVITITTTGYGDFTPKTFLGRTLTVVYLCVGVGIVMYLFSLIAEFIVEGKFEEFVRLKKMKNKIKTLKDHYIICGYGRLGKVVGEKFIEENIPFIAIDINEDVLKEEYEKYPDKFLYIVGDAKKEEVLKKAKIDKAKGLIATLPSDADNVFLTLTARELNPNILITAKADEKEAIRKLKIAGANRVVSPYLIGGLRMAEVSVRPGILDFLSTFIKIAKDEYEEDIELRKFVIEKDSELAYKSLKDANIRGKTGATILGIRREKEFCINPYPEFILKPGDVIYAFGTEENLKYLENLVKKKKKKL
What is the function of this protein?
Probable potassium channel protein.
What are the official names of this protein?
Probable potassium channel protein 2, MjK2.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MU162_SCHPO
Sequence: MDDEVYKQRLTALNNLRIVIFFDILIILLGYIGTWNLKTLQLVNPSLWSFSPSLWIYIRGTVLCADCIFTAGSANEYSAVQNSVFQVSSLMFYGLMMEFFGYSFDRVGCMELAFISFSAACYFNIRSIKSLSLKNKNWTIISIIEIPIKLHFILNVLLFLKFSEYMLPLLGRVHLSYHLFALWVINLYIWIKLIDSKDFVLGFLAGLSVLLLNTGSLITAKPLISYFNLLTSCLIIFPSIWIYAIEKKNFKNLSYEDDDYRNYW
What is the function of this protein?
Has a role in meiosis.
What are the official names of this protein?
Meiotically up-regulated gene 162 protein.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: TX2_LOXIN
Sequence: MKLLFEGLLVLVLIAFVVAEFESDAEKWEALITQERACKGEGVKGCYYEADDWCCKKTPCKCPAWSHERECRCTQPCNPSCRGKRALMVDPETHRMLSLHRLSEE
What is the function of this protein?
Toxin active against insects (S. frugiperda larvae).  May act on sodium (Nav) or calcium (Cav) channels.
What are the official names of this protein?
U1-sicaritoxin-Li1b, U1-SCRTX-Li1b, LiTx2.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 28 (Litx) family.