PharMolix/UniProtQA huggingface dataset:
Protein: RECA_ACIB5
Sequence: MDENKSKALQAALSQIEKQFGKNTVMRLGDNTVQAVEAVSTGSLTLDIALGIGGLPKGRIIEIYGPESSGKTTMTLQAIAQCQKSGGTCAFIDAEHALDPQYARKLGVDIDNLLVSQPDNGEQALEIADMLVRSGAIDLIVVDSVAALTPKAEIEGEMGDSHMGLQARLMSQALRKITGNAKRSNCMVIFINQIRMKIGVMFGSPETTTGGNALKFYASVRLDIRRIGQVKEGDEIVGSETKVKVVKNKMAPPFKEAIFQILYGKGTNQLGELVDLAVQQDIVQKAGAWYSYQGNKIGQGKNNVIRYFEENTQIAEEIERNIREQLLTTGTNGAVQIEDEEEPDLLLES
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_STRP4
Sequence: MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVDKPEGITLNDTADLTEIISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGKYIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1450_HAEIN
Sequence: MTTEIKKLDPDTAIDIAYDIFLEMAGENLDPADILLFNLQFEERGGVEFVETADDWEEEIGVLIDPEEYAEVWVGLVNEQDEMDDVFAKFLISHREEDREFHVIWKK
What are the official names of this protein?
UPF0263 protein HI_1450.
What is the protein family that this protein belongs to?
Belongs to the UPF0263 family.
Protein: Y554_XANAC
Sequence: MLMSDSLNAAALDQLFRTARTQNAFADTPVSHEVLRELYELVKWGPTAANSCPARFVFVTSAEGKAKLKPALSEGNAAKTLAAPVTVIVAHDEDFHEKLPYLFPHADAKSWFDGPREGRTESAFRNGSLQGAYLILAARALGLDAGPMSGFDNAKVDAAFFAGTPIKSNFLVNLGYGDPAGLFPRSPRLSFDEAARFE
What are the official names of this protein?
Putative NADH dehydrogenase/NAD(P)H nitroreductase XAC0554.
What is the protein family that this protein belongs to?
Belongs to the nitroreductase family. HadB/RutE subfamily.
Protein: PETN_CALFG
Sequence: MDIVSLAWAALMVVFTFSLSLVVWGRSGL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 8, Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PetN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: NIFJ_ENTAG
Sequence: MPGKMKTMDGNTAAAYVSYAFTDVTAIYPITPSTPMAESVDEWAAQGKKNLFGQTVKIMEMQSESGAAGAIHGALQAGALATTYTASQGLLLMTPNMYKIAGELLPAVFHVSARALATNSLNIFGDHQDSYAVRHTGCAMLAESSVQQVMDLAAVAHLTAIKGRIPFINFFDGFRTSHEIQKIEVLDYEDLAHLLDRDAVARFRQNALHPDHPVVRGTAQNPDIYFQEREASNKFYMALPEMVESYMAKISALTGREYHLFNYYGAPDAGRMIIAMGSVCETIQETVDYLNARGEKVGVLTVHLYRPFSLKHFFKYIPKSVSNIAVLDRTKEPGSLAEPLYLDVKSAFYNSDWRPVIVGGRYALGGKDILPSHIISIFDNLAAERPRDGFTVGINDDVTFTSLPLSDRDIDTSSSGTTACKFWGLGSDGTVGANKSAIKIIGDKTDMYAQAYFAYDSKKSGGVTMSHLRFGHNPIRSPYLIDKADFISCSQQSYVNKYHLLAGLKPGGTFLLNCSWDVAELDEKLPVAMKRYIAANDIQFYIVNAVGIAQKLGLGGRFNMIMQSAFFKLADIIPLTRAVEYLKQSIEHAYGNKGQKIVDMNNLAVDSGIESVVKISVPQAWKHLEDKVVSPKKLPAFIKDILIPMNRQEGDSLPVSIFDGIEDGTFPSGTSAYEKRGVAINVPVWQTDKCTQCNQCAFICPHAAIRPVLISEEERQNAPAGFSAKRASGTEDAWYRLAVSPLDCSGCGNCADVCPVKGKALSMQPLESQEHEIELWEYALSLTPKANPQNKFTVKGSQFEQPLLEFSGACGGCGETPYAKLVTQLFGDRMMIANATGCSSIWGASAPSIPYTTNHKGQGPTWANSLFEDNAEFGLGMLLGVDAIRDTLATQVKAALDNAPDVPLDAELSACLSDWLANKDQGEGTRERAEKVGDTSGFANAREKSRTPTVSMPHRDYLANGSHWIFGGDGWAYDIGFGGLDHVLASGKDVNVLVFDTEVYSNTGGQSSKSTPAAAIAQFACKKTRKKDLGMMAMSYGYVYVAQIAMGADKNQTLRAIAEAEAYPGPSLIIAYAACINHGLRIGMGCSQREARRAVEAGYWANYRYHPELKEAGKNPFILDSEEPEEDFQAFLAGEVRYSSLKKLYPEFAEFLFKKTEDDARERLEGYKKLASS
What is the function of this protein?
Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin, which reduces nitrogenase.
What are the official names of this protein?
Pyruvate-flavodoxin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
Protein: SHR2_STRPU
Sequence: MGMVSSQATPVEAYKVQQVQINDQTVEQLVRVQTSAGTTVTTIDAATAERLVKLREEDLIKFSAQGMSQAQMMAKPGMTSPRPIELCAVCGDKASGRHYGAISCEGCKGFFKRSIRKHLGYTCRGNKDCQIIKHNRNRCQYCRLQKCLDMGMKSDSVQCERSPLKTRDKTPGNCAASTDKIYIRKDIRSPLTATPTFVTGSVLAGGDMKSPQGNRQGLFDQGILLNVQTTPTSSPSASTSDSTTDLSTLASVVTSLANMNKKTEEGPSHSQQIYSPSQTLQIISNGDQDVQGGGDNVSKAFDALTKALNTSGDSEAGDLSIDQSANGGSSEVELVKLDSPMLSDHHMQFKLTTPSPMPQFLNVHYICESASRLLFLSMHWARSLPAFQVLSADTHTSMVQKCWSELFTLGLAQCAQAMALSTILTAIVNHLQTSLQQDKLSADRVKAVMEHIWKLQEFVTTTSKLDVDQTEFAYLKTIVLFSPDHPGLSNVRQIEKFQEMAISELHDYEAQTYPSKLNRFSKLLLRLPTLRLLSPAIMEELFFAGLIGNVQIDSIIPYILRMETADYNSAQITMSASPGSLIG
What is the function of this protein?
Orphan nuclear receptor.  Binds to the hormone response element in the upstream promoter region of the CYIIIB gene in vitro.  Both isoform 1 and isoform 2 bind DNA.
What are the official names of this protein?
Orphan steroid hormone receptor 2, SpSHR2.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=The subcellular location of isoform 1 alters throughout development. In the unfertilized egg, isoform 1 expression is cytoplasmic and concentrated around the pronucleus. Following fertilization, the cytoplasmic protein rapidly enters the embryonic nuclei where it appears as speckles. From the fourth cleavage stage onwards it resides as speckles in the cytoplasm and the nucleus. The cytoplasmic localization also differs between cells, maintaining an apical position in polarized ectodermal and endodermal cells, whereas in non-polarized cells the cytoplasmic distribution is uniform. In contrast, isoform 2 resides in the nucleus in both 4-cell and 16-cell embryos.
Protein: BIOB_STRMK
Sequence: MAAAIRHDWQHDELQALFDLPFPELLFRAAAVHREHFDPAQVQVSTLLSVKTGGCPEDCAYCPQAQRYSTGVNAQKLMETDAVLAKARQAKAAGASRFCMGAAWRSPKDRDIPKVAAMIAGVKALGLETCATLGMLSGEQARALKDAGLDYYNHNLDTAPDYYDSIIHTRQYQDRLDTLEHVRDAGLKTCCGGIVGMGETRAQRVGLLLALASLPAHPDSVPINKLVQVAGTPLHGSAELDPFEFVRMIAVARIAMPRSMVRLSAGREAMSDELQALCFLAGANSIFYGDKLLTTGNPESERDLALFARLGLQPMAVQVDAEGHDHGGTVHADISADTPGCGCAHAA
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: LMBL2_MOUSE
Sequence: MEKPRGTEEAPSSEPMEEEEEDDLDLFGGYDSFRSYNSSAGSESSSYLEESSEAENEDREAGELPTSPLHLFSSANNRSLDGSGSEPAVCEMCGIVGTREAFFSKTKRFCSVSCSRSYSSNSKKASILARLQGKPPTKKAKVLHKAAWSAKIGAFLHAQGTGQLADGTPTGQDALVLGFDWGKFLKDHSYKAAPVSCFKHVPLYDQWEDVMKGMKVEVLNSDAVLPSRVYWIATVIQAAGYRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPPRTIHAKFTDWKSYLMKRLVGSRTLPADFHIKMVESMKYPFRQGMRLEVVDKTQVSRTRMAVVDTVIGGRLRLLYEDGDSDDDFWCHMWSPLIHPVGWSRRVGHGIKMSDRRCDMSHHPTFRKIYCDAVPYLFKKVRAVYTEGGWFEEGMKLEAIDPLNLGSICVATICKVLLDGYLMICVDGGPSTDGSDWFCYHASSHAIFPATFCQKNDIELTPPKGYETQPFAWETYLEKTKSKAAPARLFNMDCPNHGFKVGMKLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDNEYDQWVDCESPDIYPVGWCELTGYQLQPPVSAEPNTPQKGKDTTKKKKKQFGKKRKRIPSAKTRPLRQGSKKPLLEDNLEALGVSEPVPDDIIAVCVKEEHQDISSLDRSPSPQLPLPIESIKQERNN
What is the function of this protein?
Putative Polycomb group (PcG) protein.  PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility.  Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis.  Binds to monomethylated and dimethylated 'Lys-20' on histone H4.  Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27' (By similarity).
What are the official names of this protein?
Lethal(3)malignant brain tumor-like protein 2, L(3)mbt-like protein 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: LRS4_YEAST
Sequence: MTTLLQLLSNYYKAKLDSERIYNEYVQSQYEFASLDKLNNNKGDPKKVVDETLFLQRQIAQLNKQLQLSFQENEKLLSVQKNQKALYQSKLSSKDAFIDDLKLKLKVEQISVDKHNKERTPSTGRDEQQRNSKAAHTSKPTIHLLSPIVNRDKPNNQTNDRGGNDPDSPTSQRRSRGLRSLLSSGKNTIFDSISKNLDDEINENAHIRNDTTSSKIAGKSPSRLSALQKSPELRKERNNMILKEHILRSKDDQNITSSRKLDNIELSSIGDSTAMTSRSSTVNANDILGNEENDGITKLKRVNKLTSSPVKRDCSTNKKRKLTKQRIATLPNSDEELSNNLNVDEFV
What is the function of this protein?
Component of the monopolin complex which promotes monoorientation during meiosis I, required for chromosome segregation during meiosis.  Involved in rDNA silencing.
What are the official names of this protein?
Monopolin complex subunit LRS4, Loss of rDNA silencing protein 4.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Chromosome, centromere. Note=Transiently released from the nucleolus and localized to the centromere regions during late pachytene. This relocation is CDC5 dependent.
Protein: CHED_THEMA
Sequence: MKKVIGIGEYAVMKNPGVIVTLGLGSCVAVCMRDPVAKVGAMAHVMLPDSGGKTDKPGKYADTAVKTLVEELKKMGAKVERLEAKIAGGASMFESKGMNIGARNVEAVKKHLKDFGIKLLAEDTGGNRARSVEYNIETGKLLVRKVGGGEQLEIKEI
What is the function of this protein?
Deamidates glutamine residues on chemoreceptors (MCPs).  CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase.  In addition, demethylates methylated glutamate residues on chemoreceptors Mcp2 and Mcp4.  Enhances the activity of CheC.
What are the official names of this protein?
Chemoreceptor glutamine deamidase CheD, Chemoreceptor glutamate methylesterase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: SPEA_SALCH
Sequence: MSSQEASKMLRTYNIAWWGNNYYDVNELGHISVCPDPDVPEARVDLAKLVKAREAQGQRLPALFCFPQILQHRLRSINAAFKRARESYGYNGDYFLVYPIKVNQHRRVIESLIHSGEPLGLEAGSKAELMAVLAHAGMTRSVIVCNGYKDREYIRLALIGEKMGHKVYLVIEKMSEIAIVLEEAERLNVVPRLGVRARLASQGSGKWQSSGGEKSKFGLAATQVLQLVETLRDAGRLDSLQLLHFHLGSQMANIRDIATGVRESARFYVELHKLGVNIQCFDVGGGLGVDYEGTRSQSDCSVNYGLNEYANNIIWAIGDACEEHGLPHPTVITESGRAVTAHHTVLVSNIIGVERNEYTDPTAPAEDAPRALQNLWETWQEMHKPGTRRSLREWLHDSQMDLHDIHIGYSSGAFSLQERAWAEQLYLSMCHEVQKQLDPQNRAHRPIIDELQERMADKMYVNFSLFQSMPDAWGIDQLFPVLPLEGLDQVPERRAVLLDITCDSDGAIDHYIDGDGIATTMPMPEYDPENPPMLGFFMVGAYQEILGNMHNLFGDTEAVDVFVFPDGSVEVELSDEGDTVADMLQYVQLDPKTLLTHFRDQVKQTDLDDALQQQFLEEFEAGLYGYTYLEDE
What is the function of this protein?
Catalyzes the biosynthesis of agmatine from arginine.
What are the official names of this protein?
Biosynthetic arginine decarboxylase, ADC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
Protein: OMPC_SALTY
Sequence: MKVKVLSLLVPALLVAGAANAAEIYNKDGNKLDLFGKVDGLHYFSDDKGSDGDQTYMRIGFKGETQVNDQLTGYGQWEYQIQGNQTEGSNDSWTRVAFAGLKFADAGSFDYGRNYGVTYDVTSWTDVLPEFGGDTYGADNFMQQRGNGYATYRNTDFFGLVDGLDFALQYQGKNGSVSGENTNGRSLLNQNGDGYGGSLTYAIGEGFSVGGAITTSKRTADQNNTANARLYGNGDRATVYTGGLKYDANNIYLAAQYSQTYNATRFGTSNGSNPSTSYGFANKAQNFEVVAQYQFDFGLRPSVAYLQSKGKDISNGYGASYGDQDIVKYVDVGATYYFNKNMSTYVDYKINLLDKNDFTRDAGINTDDIVALGLVYQF
What is the function of this protein?
Forms pores that allow passive diffusion of small molecules across the outer membrane.
What are the official names of this protein?
Outer membrane porin C, Outer membrane protein C, Porin OmpC.
What is the protein family that this protein belongs to?
Belongs to the Gram-negative porin family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: VIAA_SALNS
Sequence: MLTLDTLNTMLAVSEEGMVEEMILALLASPQLVIFFEKFPRLKNAVTADLPRWREALRSRLKDARVPPELTEEVMCYQQSQLLSTPQFIVQLPQILALLHRLHSPYAAQAKQLTESNSTFTPALHTLFLQRWRLSLVVQATTLNQQLLEEEREQLLSDVQERMTLSGQLEPTLAENDNAAGRLWDMSAGQLKRGDYQLIVKYGEFLAAQPELMQLAEQLGRSREAKSVPKKDAPMETFRTLVREPATVPEQVDGIQQGDDILRLLPPELATLGITELEYEFYRRLVEKQLLTYRLHGEAWREKVTERPVVHQDVDEQPRGPFIVCVDTSGSMGGFNEQCAKAFCLALMRVALADNRRCFIMLFSTDVVRYELSGPEGIEQAIRFLSQRFRGGTDIASCFRAIIERMQGREWFDADAVVISDFIAQRLPDDVVSKVGELQRLHQHRFHAVAMSAHGKPGIMRIFDHIWRFDTGMRSRLLRRWRR
What are the official names of this protein?
Protein ViaA, VWA domain protein interacting with AAA ATPase.
What is the protein family that this protein belongs to?
Belongs to the ViaA family.
Protein: MOAC_BURCM
Sequence: MSGLTHFDAAGHAHMVDVGGKQETQRIAIARGTIRMLPATFALIRDGKAKKGDVLGVARIAAIQGAKRTADLIPLCHPLALTRVAVDFELDDALPGVHCVAQVETFGRTGVEMEALTAVQVGLLTVYDMCKAVDRGMVITEVSVREKRGGKSGDWKAEDTAG
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: FBK58_ARATH
Sequence: MTTISDLPYDLLPEILSRLPTKSIPKLKTTCKKWYALFKDPKFVEKKLGKAARETVFLMNHEVNSISVDIHGIPKGYSVSMDFTGTLTIPEGSDLEIFRIHHCNGLFLCATMNCRLVVWNPCTGQITWIIPRTRYDSDDIYALGCGDDKSSSLHSYKILRCCDDNQKKPVSEIYDFSSSSWRVLDGVTANCFIECNGVALKESAYWYASDKRETPKGKFILRFDFATERFARLCLPLNFQRDRDNKSVVVSVVGEEKLALLQQFDHRVHGLKYSKIKIWVTDTKIGEGKDLSWSNILVEELADDNLPSVTSFLLDEEKKVAVCSDAVCSDTDTEDEDRRRIYIVGEGVDEFVYDEVSTETSHNWPFLVSYVPNLVHIEKDAPIVEV
What are the official names of this protein?
Putative F-box/kelch-repeat protein At3g17280.
Protein: KHSE_CHLT3
Sequence: MKQVTGFAPASVGNVACGFDVLGFALTEPGDEVTVSFTDDENSPAQVIISKIIGDGGALPTDPYKNTASIVVIKFLEFLKTHKGIEQSGTFSIELKKNLPLSSGMGSSASSAAAALIAANSLLGSPCTKMELVPFVMEGERIACGSIHADNAAPAMLGNFILTRSYDPLDLIPISTPPELYCSLVHPHIEVPTSHARSILKKEIALSSAVRQWGNVGALVAGLLRCDYELIGRALEDVVAEPVRAPLIPGFYDVKHAALDAGALGGSIAGSGPSIFAFSDSLAKAETIAKAMQETFRKVSNLESDIWFCPVSREGSRIL
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UN13D_HUMAN
Sequence: MATLLSHPQQRPPFLRQAIKIRRRRVRDLQDPPPQMAPEIQPPSHHFSPEQRALLYEDALYTVLHRLGHPEPNHVTEASELLRYLQEAFHVEPEEHQQTLQRVRELEKPIFCLKATVKQAKGILGKDVSGFSDPYCLLGIEQGVGVPGGSPGSRHRQKAVVRHTIPEEETHRTQVITQTLNPVWDETFILEFEDITNASFHLDMWDLDTVESVRQKLGELTDLHGLRRIFKEARKDKGQDDFLGNVVLRLQDLRCREDQWYPLEPRTETYPDRGQCHLQFQLIHKRRATSASRSQPSYTVHLHLLQQLVSHEVTQHEAGSTSWDGSLSPQAATVLFLHATQKDLSDFHQSMAQWLAYSRLYQSLEFPSSCLLHPITSIEYQWIQGRLKAEQQEELAASFSSLLTYGLSLIRRFRSVFPLSVSDSPARLQSLLRVLVQMCKMKAFGELCPNTAPLPQLVTEALQTGTTEWFHLKQQHHQPMVQGIPEAGKALLGLVQDVIGDLHQCQRTWDKIFHNTLKIHLFSMAFRELQWLVAKRVQDHTTVVGDVVSPEMGESLFQLYISLKELCQLRMSSSERDGVLALDNFHRWFQPAIPSWLQKTYNEALARVQRAVQMDELVPLGELTKHSTSAVDLSTCFAQISHTARQLDWPDPEEAFMITVKFVEDTCRLALVYCSLIKARARELSSGQKDQGQAANMLCVVVNDMEQLRLVIGKLPAQLAWEALEQRVGAVLEQGQLQNTLHAQLQSALAGLGHEIRTGVRTLAEQLEVGIAKHIQKLVGVRESVLPEDAILPLMKFLEVELCYMNTNLVQENFSSLLTLLWTHTLTVLVEAAASQRSSSLASNRLKIALQNLEICFHAEGCGLPPKALHTATFQALQRDLELQAASSRELIRKYFCSRIQQQAETTSEELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPELAARETQKHKKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEGEAFLPLREVPGLSGSEEPGEVPQTRLPLTYPAPNGDPILQLLEGRKGDREAQVFVRLRRHRAKQASQHALRPAP
What is the function of this protein?
Plays a role in cytotoxic granule exocytosis in lymphocytes.  Required for both granule maturation and granule docking and priming at the immunologic synapse.  Regulates assembly of recycling and late endosomal structures, leading to the formation of an endosomal exocytic compartment that fuses with perforin-containing granules at the immunologic synapse and licences them for exocytosis.  Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells.
What are the official names of this protein?
Protein unc-13 homolog D, Munc13-4.
What is the protein family that this protein belongs to?
Belongs to the unc-13 family.
Protein: PSA4B_ARATH
Sequence: MSRRYDSRTTIFSPEGRLYQVEYAMEAIGNAGSAIGILAKDGVVLVGEKKVTSKLLQTSSSMEKMYKIDDHVACAVAGIMSDANILINTARVQAQRWDRNHGFQLYMSDPSGNYGGWQAAAVGANNQAAQSILKQDYKDDATREEVVQLAIKVLSKTMDSTSLTAEKLELAELYLTPSKCVKYHVHSPDSLTKLLVKHGVTQPAAETS
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity (By similarity).
What are the official names of this protein?
Putative proteasome subunit alpha type-4-B, 20S proteasome alpha subunit C-2, Proteasome subunit alpha type-3.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DGGGP_METTH
Sequence: MNPYIEILRPVNAVMAVITVMLMALITGRFDFSVLLASVVVFTATGAGNVINDYFDHEIDAINRPERPIPSGRISRGVAGVYSIILFALASLMGFYLGLLPGLVVVSSSLLMVYYAWRLKKRCLVGNITISFLTGLSFVFGGIVLGEVRASILLGFYAFLMTMAREIVKDMEDVEGDRAEGATTLPITHGMRISGVLAASFMLIASLTSPSLYLLGIFSALYIPVLLLAVAVFLRAAIMILRGQDRATASRVSRMIKVGMALTFIAFAAGSGTITALTGLS
What is the function of this protein?
Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP).  This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
Digeranylgeranylglyceryl phosphate synthase, DGGGP synthase, DGGGPS, (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase, Geranylgeranylglycerol-phosphate geranylgeranyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. DGGGP synthase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ZC3HF_HUMAN
Sequence: MPPKKQAQAGGSKKAEQKKKEKIIEDKTFGLKNKKGAKQQKFIKAVTHQVKFGQQNPRQVAQSEAEKKLKKDDKKKELQELNELFKPVVAAQKISKGADPKSVVCAFFKQGQCTKGDKCKFSHDLTLERKCEKRSVYIDARDEELEKDTMDNWDEKKLEEVVNKKHGEAEKKKPKTQIVCKHFLEAIENNKYGWFWVCPGGGDICMYRHALPPGFVLKKDKKKEEKEDEISLEDLIERERSALGPNVTKITLESFLAWKKRKRQEKIDKLEQDMERRKADFKAGKALVISGREVFEFRPELVNDDDEEADDTRYTQGTGGDEVDDSVSVNDIDLSLYIPRDVDETGITVASLERFSTYTSDKDENKLSEASGGRAENGERSDLEEDNEREGTENGAIDAVPVDENLFTGEDLDELEEELNTLDLEE
What is the function of this protein?
Protects DRG1 from proteolytic degradation (PubMed:19819225).  Stimulates DRG1 GTPase activity likely by increasing the affinity for the potassium ions (PubMed:23711155).
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 15, DRG family-regulatory protein 1, Likely ortholog of mouse immediate early response erythropoietin 4.
What is the protein family that this protein belongs to?
Belongs to the ZC3H15/TMA46 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=The DRG1- DFRP2/ZC3H15 complex associates with polysomes.
Protein: TKN_ELEMO
Sequence: QPSKDAFIGLM
What is the function of this protein?
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.
What are the official names of this protein?
Eledoisin.
What is the protein family that this protein belongs to?
Belongs to the tachykinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: G3P2_CANGA
Sequence: MVRIAINGFGRIGRLVLRVALSRSNIEVVAVNDPFITTDYAAYMFKYDSTHGRYAGEVTHDDKHIIIDGKKIAVHQERDPANLPWGSENIDIAIDSTGVFKELDTAQKHIDAGAKKVVITAPSSTAPMFVVGVNEDKYTSDLKIVSNASCTTNCLAPLAKVIDEAFGIEEGLMTTVHSLTATQKTVDGPSHKDWRGGRTASGNIIPSSTGAAKAVGKVLPQLQGKLTGMAFRVPTVDVSVVDLTVKLQKETTYDEIKKVIKQASEGKLKGVLGYTEDAVVSSDFLGDSRSSIFDASAGIQLSPKFVKLVSWYDNEYGYSTRVVDLVEHVAKN
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase 2, GAPDH 2.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDUF7_HUMAN
Sequence: MSVLLRSGLGPLCAVARAAIPFIWRGKYFSSGNEPAENPVTPMLRHLMYKIKSTGPITVAEYMKEVLTNPAKGYYVYRDMLGEKGDFITSPEISQIFGELLGIWFISEWMATGKSTAFQLVELGPGRGTLVGDILRVFTQLGSVLKNCDISVHLVEVSQKLSEIQALTLTKEKVPLERNAGSPVYMKGVTKSGIPISWYRDLHDVPKGYSFYLAHEFFDVLPVHKFQKTPQGWREVFVDIDPQVSDKLRFVLAPSATPAEAFIQHDETRDHVEVCPDAGVIIEELSQRIALTGGAALVADYGHDGTKTDTFRGFCDHKLHDVLIAPGTADLTADVDFSYLRRMAQGKVASLGPIKQHTFLKNMGIDVRLKVLLDKSNEPSVRQQLLQGYDMLMNPKKMGERFNFFALLPHQRLQGGRYQRNARQSKPFASVVAGFSELAWQ
What is the function of this protein?
Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I) (PubMed:20406883, PubMed:24089531, PubMed:24838397).  Acts by mediating symmetric dimethylation of 'Arg-118' of NDUFS2 after it assembles into the complex I, stabilizing the early intermediate complex (PubMed:24089531).
What are the official names of this protein?
Protein arginine methyltransferase NDUFAF7, mitochondrial, NADH dehydrogenase [ubiquinone] complex I, assembly factor 7, Protein midA homolog.
What is the protein family that this protein belongs to?
Belongs to the NDUFAF7 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: AIFM3_HUMAN
Sequence: MGGCFSKPKPVELKIEVVLPEKERGKEELSASGKGSPRAYQGNGTARHFHTEERLSTPHPYPSPQDCVEAAVCHVKDLENGQMREVELGWGKVLLVKDNGEFHALGHKCPHYGAPLVKGVLSRGRVRCPWHGACFNISTGDLEDFPGLDSLHKFQVKIEKEKVYVRASKQALQLQRRTKVMAKCISPSAGYSSSTNVLIVGAGAAGLVCAETLRQEGFSDRIVLCTLDRHLPYDRPKLSKSLDTQPEQLALRPKEFFRAYGIEVLTEAQVVTVDVRTKKVVFKDGFKLEYSKLLLAPGSSPKTLSCKGKEVENVFTIRTPEDANRVVRLARGRNVVVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRFLGERVGRALMKMFENNRVKFYMQTEVSELRGQEGKLKEVVLKSSKVVRADVCVVGIGAVPATGFLRQSGIGLDSRGFIPVNKMMQTNVPGVFAAGDAVTFPLAWRNNRKVNIPHWQMAHAQGRVAAQNMLAQEAEMSTVPYLWTAMFGKSLRYAGYGEGFDDVIIQGDLEELKFVAFYTKGDEVIAVASMNYDPIVSKVAEVLASGRAIRKREVELFVLHSKTGDMSWLTGKGS
What is the function of this protein?
Induces apoptosis through a caspase dependent pathway.  Reduces mitochondrial membrane potential.
What are the official names of this protein?
Apoptosis-inducing factor 3, Apoptosis-inducing factor-like protein.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase family.
What are the subcellular locations of this protein?
Mitochondrion. Note=Does not translocate to the nucleus upon induction of apoptosis.
Protein: LDH_CORJK
Sequence: MTAPQPHTITPPTPGSKIVLIGAGDVGIAYAYTLVNQGLTDHLAIIDLDERKTWGHVQDLNHAVPWSHHNTRVTVGTYEDCRDAAMVCICAGAAQKPGETRLDLVAKNTAIFKTIVGDVMSHGFNGIFLVASNPVDILSYATWKFSGMDSSRVIGSGTILDTARFRYALGRYFDLAPTSVHAYVIGEHGDTELPVLSAGSVAGTSIHHRLEMIGESADEDVDEIFVKTRDAAYEIIQAKGSTSFGIGMGLARITQAVFSNQDVVLPISTLLQGEYGFEDIYIGTPAVINRQGVRHAVELQLDSEEKERFDHSANVLRKVMGEAGLI
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.