PharMolix/UniProtQA huggingface dataset:
Protein: GATC1_CULQU
Sequence: MIRIPFRLRPPPGRTLHSLVRTFASTKPADLTGTQEKNTRQKINFHELKHPSKVPQRPHKSTTTVGQSTPTRIPVDAQTVQLLERLSLVDLDSAEAHRTLEDAIEFASQILSVDTEGVEPLYTVLERERLTLREDRVTDGNIQQDVLRNARVTEEEYFVAPPGNIPLEQEPRK
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit C-1, mitochondrial, Glu-AdT subunit C-1.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SCPA_BACCR
Sequence: MQYNFKVEAFEGPLDLLLHLIHRYEIDIYNIPVADITEQYLSYVHTMKELQLDVASEYLVMAATLLQIKSKMLLPKHEEDVLDNGDDFIDDPRQELMERLIEYKKYKQVATELKEREQERAQLYTRPPIDFTSLQQEEETSLPLDVTLYDMLAAFQKLMRRKKAKKPVTTRITRQEIPIEQRMTDILKQLKIKGGRQSFYDLFVDDEREIMVVTFLAVLELMKNQQIIIEQEHNFDEIFVSSSNKSA
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein A.
What is the protein family that this protein belongs to?
Belongs to the ScpA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: GLPK_PSEPK
Sequence: MTDTQDKNYIIALDQGTTSSRAIIFDRDANVVGTSQREFAQHYPQAGWVEHDPMEIFATQSATMVEALAQAGISHAQVAALGITNQRETTVVWDKETGRPVYNAIVWQCRRSTEICAQLKRDGHEDYIRETTGLVTDPYFSGTKLKWILDNVDGARERAERGELLFGTIDTWLIWKLTGGKVHVTDYTNASRTLMFNIHSLQWDDKLLEILGIPRQMLPEVRPSSEVYGHTKSGIAIAGIAGDQQSALFGQMCVEPGQAKNTYGTGCFLLMNTGDQAVKSSHGLLTTIACGPRGEVAYALEGAVFNGGSTVQWLRDELKIVNDALDTEYFASKVKDSNGVYLVPAFTGLGAPYWDPYARGALFGLTRGVKVDHIIRAALESIAYQTRDVLDAMQQDCGQRLSELRVDGGAVANNFLMQFQADILGTCVERPQMRETTALGAAYLAGLACGFWSGLDELRDKAIIEREFSPQLDETQKEKLYAGWKKAVERTRDWEDHEA
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: NTPP_GRABC
Sequence: MKLILASASSARRSMLEQAGIDAESIPAAVDEDMVKQSMRAEGASAAETATALAHLKAERISRRYPDSVVIGSDQLLVCEGAWFDKAPDLERARARLLDFRGRAHHLVTSVVCAKGGSRLWHHVETPCLHMRRFSEDFLNRYLAQEGEALLGSVGCYRLEGPGIQLFDRIEGDYFSILGMPLLPLLGFLRQHQALTV
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAL1_PECAS
Sequence: MNQLEALKQFTVVVADSGDIDSIRQFSPQDATTNPSLILKAATLPQYQPLFDDAIAYANLQGGSPETRLINASDRLAVNIGAEVLKSIPGRISTEVDARLSFDRGMCVAKARKLIGMYQEKDIPRSRILIKLAATWEGIRAAEELEKEGINCNLTLLFSFAQARACAEAGVFLISPFVGRIYDWYQEKQPTSDYQAESDPGVISVRDIYDYYKRHRYQTVIMGASFRKVEQILALAGCDRLTISPALLEQLKNSSDPVERQLTPSTEAFHPPSPLSEAEFRWEHHQDAMAVDKLAEGIRLFAADQQKLEALLAAKL
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase 1.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIF3A_MAGO7
Sequence: MPPPPHQKPENVLKRAHELIGVNQAPAALTLLHEHITSKRSRNVPIASLEPVMVLLVELSVEQKKGKLAKDALYQYKNIAQNTNVGTIELVLKKFIELAAGKVTAAQQKADEVQSSIEATNSTSVDDLEATETPESILLATVSGEQSRDRTDRAIVTPWLKFLWEAYRTVLDILRNNARLELLYQSTAMQAFEFCLKYIRKTEFRRLCELLRNHVQTAAKYSTQMHAINLNDPDTLQRHLETRFQQLNVAVELELWQEAFRSVEDIHTLLNLSKRPPKNIMMANYYEKLTRIFLVGENYLFHAAAWSRYYSLLRQSAAVVASGQGKKADNPPATPADLQKAASFVLLSALSIPVISTTRSRGAMVDFDEAKKNKNSRLTHLLNMSQAPTRAVLFKDAMSKSLLNQARPEIRDLYNILEVDFHPLSICKKISPILAQIGADEDMKKYVLPLQQVILTRLFQQLSQVYETVDLEFVESLAQFPEPFQVTRATVEKFIMNGNKKGDLSIRMDHGTGVLSFDTDIFSSSKASHSGSAAGSAEAEGGSVQRLQRTPSEIVRSQLVRLGRALYTTCYYVDPSFNESRVKAREAALARAKAGAEKEHREILARKDIIQKRKEEASDLQAKREKENAKIKRMREQALLEAEQQRLAEEQKERERKRKEKEMQEIRKQEAESLIKDLKIGPNALDVSAEDLANLDTSQIRAIKVAQLEREKNDINEKLRITGKRLDHLERAYRKEEVKKLHEDYESQKKRDLDAYSKIKEETLKESKIKHEESVELKHRLSRLMPFYEEFRANLQERRRDEFEKRRRDAERELEKQIAQRKKEYREKKLREKRQREEEERQLREAEERAAKEKEEQKRREEARKEELARAKAQREAERQEMAEKAALQARREEEALERRKREKEKLASAPPASAAPVRASESAGGPPRLNLAGAGGKPSWRDRVPSSNVGAAPSERSERPSERPAPARTGTPMERTDSNDRAGGPPRLNLARADGAKPSWREREQAKASGGPERDLPPSRAASGRGPPMHRTDSGRGENGRDESPAPPRDSLTASGAPGKYVPRWKRENAGN
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit A, eIF3a, Eukaryotic translation initiation factor 3 110 kDa subunit homolog, eIF3 p110, Translation initiation factor eIF3, p110 subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TULP3_MOUSE
Sequence: MEAARCAPGPRGDSAFDDETLRLRQLKLDNQRALLEKKQRKKRLEPLMVQPNPEARLRRLKPRGSEEHTPLVDPQMPRSDVILHGIDGPAAFLKPEAQDLESKPQVLSVGSPAPEEGTEGSADGESPEETAPKPDLQEILQKHGILSSVNYDEEPDKEEDEGGNLSSPSARSEESAAASQKAASETGASGVTAQQGDAQLGEVENLEDFAYSPAPRGVTVKCKVTRDKKGMDRGLFPTYYMHLEREENRKIFLLAGRKRKKSKTSNYLVSTDPTDLSREGESYIGKLRSNLMGTKFTVYDHGVNPVKAQGLVEKAHTRQELAAICYETNVLGFKGPRKMSVIIPGMNMNHERIPFRPRNEHESLLSKWQNKSMENLIELHNKAPVWNDDTQSYVLNFHGRVTQASVKNFQIVHGNDPDYIVMQFGRVADDVFTLDYNYPLCALQAFAIGLSSFDSKLACE
What is the function of this protein?
Negative regulator of the Shh signaling transduction pathway: recruited to primary cilia via association with the IFT complex A (IFT-A) and is required for recruitment of G protein-coupled receptor GPR161 to cilia, a promoter of PKA-dependent basal repression machinery in Shh signaling.  Binds to phosphorylated inositide (phosphoinositide) lipids.  Both IFT-A- and phosphoinositide-binding properties are required to regulate ciliary G protein-coupled receptor trafficking.  During adipogenesis, regulates ciliary trafficking of FFAR4 in preadipocytes.
What are the official names of this protein?
Tubby-related protein 3, Tubby-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the TUB family.
What are the subcellular locations of this protein?
Nucleus. Cell membrane. Cell projection, cilium. Cytoplasm. Secreted. Note=Translocates from the plasma membrane to the nucleus upon activation of guanine nucleotide-binding protein G(q) subunit alpha (By similarity). Does not have a cleavable signal peptide and is secreted by a non-conventional pathway.
Protein: CYHEH_AFREN
Sequence: KIPCGESCVYIPCISSVLGCSCSNKVCYKD
What is the function of this protein?
Probably participates in a plant defense mechanism.
What are the official names of this protein?
Cyclotide hyen-H.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Bracelet subfamily.
Protein: PAND_FRASN
Sequence: MFRTMLNSKIHRATVTQADLHYVGSVTIDADLMAAADLLPGEQVTIVDINNGARLETYAISGPAGSGIIGINGAAARLVHPGDLVIIISYGIMDDAEARRHVPKVLFVDAENRIVGQGGDPAAALPGDPSSLRGDVLDPAGARGLGGGA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAHH_MYCTA
Sequence: MTGNLVTKNSLTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISGSLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWKGETLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAEWKVFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSVTKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEIDPINALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNEIDMAGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFANQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEGPYKPDHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YKR5_CAEEL
Sequence: MSTNLVDYVDDSYLNQSMNSENGLDSVTQIMYDMKKYNIVNDVLPPPNHEDLHVVIMAVSYLLLFLLGTCGNVAVLTTIYHVIRSSRATLDNTLIYVIVLSCVDFGVCLSLPITVIDQILGFWMFGKIPCKLHAVFENFGKILSALILTAMSFDRYAGVCHPQRKRLRSRNFAITILLVLAVYAFITLCPLLWSFTAREIILYAKETAPGMLTRMKIEKCTVDIDSQMFTAFTIYQFILCYCTPLVLIAFFYTKLLSKLREHTRTFKSSQIPFLHISLYTLAVACFYFLCWTPFWMATLFAVYLENSANSSSVPPVFVYIMYFIHALPFTNSAINWILYGALNGQLQQRYRSNRSNSTKKTTTTTASTALLEKKITNLNTNSNYQVNGSMNSIATAAPTKTIGNNEVLVATSTIDDDVATDVVDVRLLSNHNPTFL
What is the function of this protein?
Putative receptor.
What are the official names of this protein?
Probable G-protein coupled receptor C06G4.5.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UCK1_MOUSE
Sequence: MASAGGGGSESAAPEADRPQPRPFLIGVSGGTASGKSTVCEKIMELLGQNEVDRRQRKLVILSQDCFYKVLTAEQKAKALKGQYNFDHPDAFDNDLMHKTLKNIVEGKTVEVPTYDFVTHSRLPETTVVYPADVVLFEGILVFYTQEIRDMFHLRLFVDTDSDVRLSRRVLRDVQRGRDLEQILTQYTAFVKPAFEEFCLPTKKYADVIIPRGVDNMVAINLIVQHIQDILNGDLCKRHRGGPNGRNHKRTFPEPGDHPGVLATGKRSHLESSSRPH
What is the function of this protein?
Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate (PubMed:8951040).  Does not phosphorylate deoxyribonucleosides or purine ribonucleosides.  Can use ATP or GTP as a phosphate donor (By similarity).
What are the official names of this protein?
Uridine-cytidine kinase 1, UCK 1, Cytidine monophosphokinase 1, Uridine monophosphokinase 1.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
Protein: ZDHC4_MOUSE
Sequence: MDFLVLFLFYLAFLLICVVLICIFTKSQRLKAVVLGGAQVCSRVIPQCLQRAVQTLLHQLFHTRHPTFIVLHLLLQGLVYAEYTCEVFGYCRELEFSLPYLLLPYVLLSVNLVFFTLTCAANPGTITKANESFLLQVYKFDDVMFPKNSRCPTCDLRKPARSKHCRLCDRCVHRFDHHCVWVNNCIGAWNTRYFLIYLLTLTASAATIATVTAAFLLRLVTVSDLYQETYLDDVGHFQAVDTVFLIQHLFLAFPRIVFLLGFVIVLSMLLAGYLCFALYLAATNQTTNEWYKGDWAWCQRWPLVAWSPSAEPRIHQNIHSHGFRSNLREIFLPATPSYKKKEK
What is the function of this protein?
Palmitoyltransferase that could catalyze the addition of palmitate onto protein substrates including the D(2) dopamine receptor DRD2.
What are the official names of this protein?
Palmitoyltransferase ZDHHC4, Zinc finger DHHC domain-containing protein 4, DHHC-4.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: SYP43_ARATH
Sequence: MATRNRTLLFRKYRNSLRSVRAPMGSSSSSTLTEHNSLTGAKSGLGPVIEMASTSLLNPNRSYAPVSTEDPGNSSRGTITVGLPPDWVDVSEEISVYIQRARTKMAELGKAHAKALMPSFGDGKEDQHQIETLTQEVTFLLKKSEKQLQRLSAAGPSEDSNVRKNVQRSLATDLQNLSMELRKKQSTYLKRLRLQKEDGADLEMNLNGSRYKAEDDDFDDMVFSEHQMSKIKKSEEISIEREKEIQQVVESVSELAQIMKDLSALVIDQGTIVDRIDYNIQNVASTVDDGLKQLQKAERTQRQGGMVMCASVLVILCFIMLVLLILKEILL
What is the function of this protein?
Contributes to the regulation of secretory and vacuolar transport pathways in the post-Golgi network, and to the maintenance of the Golgi apparatus and trans-Golgi network (TGN) morphologies (PubMed:22307646).  Vesicle trafficking protein that functions in the secretory pathway and mediates liposome fusion (PubMed:24021022).  Required for extracellular resistance responses to a fungal pathogen (PubMed:22307646).  Also involved in the protection of chloroplasts from salicylic acid-dependent biotic stress (PubMed:22307646).  Also involved in the protection of chloroplasts from salicylic acid-dependent biotic stress (PubMed:22307646).
What are the official names of this protein?
Syntaxin-43, AtSYP43.
What is the protein family that this protein belongs to?
Belongs to the syntaxin family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Single-pass type IV membrane protein.
Protein: PSBM_ANGEV
Sequence: MEVNILAFIATALFILIPTAFLLILYVQTAAQNN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface.
What are the official names of this protein?
Photosystem II reaction center protein M, PSII-M.
What is the protein family that this protein belongs to?
Belongs to the PsbM family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: X_HBVF6
Sequence: MAARLCCQLDPARDVLCLRPVGAESSGRTLPGSLGAVPPPSSSAVPADNGSHLSLRGLPVCSFSSAGPCALRFTSARRMETTVNAPWSLPTVLHKRTLGLSGRSMTWIEDYIKDCVFKDWEELGEEIRLKVFVLGGCRHKLVCSPAPCNFFTSA
What is the function of this protein?
Multifunctional protein that plays a role in silencing host antiviral defenses and promoting viral transcription.  Does not seem to be essential for HBV infection.  May be directly involved in development of cirrhosis and liver cancer (hepatocellular carcinoma).  Most of cytosolic activities involve modulation of cytosolic calcium.  The effect on apoptosis is controversial depending on the cell types in which the studies have been conducted.  May induce apoptosis by localizing in mitochondria and causing loss of mitochondrial membrane potential.  May also modulate apoptosis by binding host CFLAR, a key regulator of the death-inducing signaling complex (DISC).  Promotes viral transcription by using the host E3 ubiquitin ligase DDB1 to target the SMC5-SMC6 complex to proteasomal degradation.  This host complex would otherwise bind to viral episomal DNA, and prevents its transcription.  Moderately stimulates transcription of many different viral and cellular transcription elements.  Promoters and enhancers stimulated by HBx contain DNA binding sites for NF-kappa-B, AP-1, AP-2, c-EBP, ATF/CREB, or the calcium-activated factor NF-AT.
What are the official names of this protein?
Protein X, HBx, Peptide X, pX.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus protein X family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Host mitochondrion. Note=Mainly cytoplasmic as only a fraction is detected in the nucleus. In cytoplasm, a minor fraction associates with mitochondria or proteasomes.
Protein: NEUT_MOUSE
Sequence: MRGMNLQLVCLTLLAFSSWSLCSDSEEDVRALEADLLTNMHTSKISKASPPSWKMTLLNVCSLINNVNSPAEEAGDMHDDDLVGKRKLPLVLDGFSLEAMLTIFQLQKICRSRAFQHWEIIQEDILDNVNDKNEKEEVIKRKIPYILKRQLYENKPRRPYILKRGSYYY
What is the function of this protein?
Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism.  It causes contraction of smooth muscle (By similarity).
What are the official names of this protein?
Neurotensin/neuromedin N.
What is the protein family that this protein belongs to?
Belongs to the neurotensin family.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic vesicle, secretory vesicle. Note=Packaged within secretory vesicles.
Protein: RL35_PSEFS
Sequence: MPKMKTKSGAAKRFLKTANGIKHKHAFKSHILTKMSTKRKRQLRGSSLLHPSDVAKVERMLRLR
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: RPPH_HAEIN
Sequence: MIDFDGYRPNVGIVICNRKGQVLWAKRCGQNSWQFPQGGINDNESAEQAMYRELHEEVGLQPKDVRLLYVSKHWLRYKLPKRLLRYDSKPMCIGQKQRWFLLQLVSDEKNINMQTTKSPEFDGWRWVSFWYPVRQVVSFKRDVYRKVMKEFASILFTDNPLIFSASREANSLHYSANKKYSQTKYTKRHFYKSRGQ
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: RL33_RIPO1
Sequence: MAAKKGVRIIITLECTECRTNTDKRSPGVSRYTTSKNRRNTTGRMEIKKFCPHCNTHTIHKEIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: FEN_ARCFU
Sequence: MGADIGDLFEREEVELEYFSGKKIAVDAFNTLYQFISIIRQPDGTPLKDSQGRITSHLSGILYRVSNMVEVGIRPVFVFDGEPPEFKKAEIEERKKRRAEAEEMWIAALQAGDKDAKKYAQAAGRVDEYIVDSAKTLLSYMGIPFVDAPSEGEAQAAYMAAKGDVEYTGSQDYDSLLFGSPRLARNLAITGKRKLPGKNVYVDVKPEIIILESNLKRLGLTREQLIDIAILVGTDYNEGVKGVGVKKALNYIKTYGDIFRALKALKVNIDHVEEIRNFFLNPPVTDDYRIEFREPDFEKAIEFLCEEHDFSRERVEKALEKLKALKSTQATLERWF
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity.  Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation.  Also involved in the base excision repair (BER) pathway.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA (By similarity).
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
Protein: Y3100_MYCBO
Sequence: MVRETRVRVARVYEDIDPDDGQRVLVDRIWPHGIRKDDQRVGIWCKDVAPSKELREWYHHQPERFDEFASRYQEELHDSAALAELRKLTGRSVVTPVTATRHVARSHAAVLAQLLNGR
What are the official names of this protein?
Uncharacterized protein Mb3100c.
What is the protein family that this protein belongs to?
To E.coli YeaO.
Protein: G6P_BPPF1
Sequence: MEWLSGFLDQIIAFFQWIWDFFAQGIYDFVRDGLVVATKASMYAALQTLILLIDVSYTAARELIDSLGVPQMIRSMYAALPGPIAAGLAFFGVPQALNIIMGRGGDALLHALRAVHWEVIRVDQDPSRPQWLLQNLRRDPG
What is the function of this protein?
Plays essential roles both in the entry of the viral genome into the bacterial host and in budding process.  The formation of the G3P-G6P complex termed adsorption complex is essential for correct termination of filamentous phage assembly (By similarity).
What are the official names of this protein?
Head virion protein G6P, Coat protein D, G6P.
What is the protein family that this protein belongs to?
Belongs to the inovirus G6P protein family.
What are the subcellular locations of this protein?
Virion. Host membrane; Multi-pass membrane protein. Note=Prior to assembly, G6P is found associated with the bacterial host inner membrane. There are about five copies of G6P in the mature virion. They are located together with G3P at the head side of the filamentous virion (By similarity).
Protein: HSAD_MYCTU
Sequence: MTATEELTFESTSRFAEVDVDGPLKLHYHEAGVGNDQTVVLLHGGGPGAASWTNFSRNIAVLARHFHVLAVDQPGYGHSDKRAEHGQFNRYAAMALKGLFDQLGLGRVPLVGNSLGGGTAVRFALDYPARAGRLVLMGPGGLSINLFAPDPTEGVKRLSKFSVAPTRENLEAFLRVMVYDKNLITPELVDQRFALASTPESLTATRAMGKSFAGADFEAGMMWREVYRLRQPVLLIWGREDRVNPLDGALVALKTIPRAQLHVFGQCGHWVQVEKFDEFNKLTIEFLGGGR
What is the function of this protein?
Catalyzes the hydrolysis of a carbon-carbon bond in 4,5: 9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate (4,9-DSHA) to yield 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oate (DOHNAA) and 2-hydroxy-hexa-2,4-dienoate (HHD).  Is also able to catalyze the hydrolysis of 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid (HOPDA) and the synthetic analog 8-(2-chlorophenyl)-2-hydroxy-5-methyl-6-oxoocta-2,4-dienoic acid (HOPODA).
What are the official names of this protein?
4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase, 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase, HOPDA hydrolase, Meta-cleavage product hydrolase, MCP hydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. HsaD family.
Protein: ISPT2_STRCO
Sequence: MRAKVRAALDALYMKRLVRELEGRPRPQHIGIMLDGNRRWAKMSGIDDPREGYRAGGAKVLDFLRWCDSAQIEHVTLFMLSDDNLARPEEQLNPLIDIIAEVVEQLAAPGNPWPVEAVGALDLLPAESASRLKTATAATQGRKGGTKVDVAVGYGGRREIVDAVRSALTEHSSQGGDIDEFIETFTMEHISKHLYSKTRSESDLIIRTSGEQRLSGFLLWQSAYAEVHFCETYWPDFREIDFLRALRSYSLRERRYGR
What is the function of this protein?
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
What are the official names of this protein?
Isoprenyl transferase 2.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: BIOD1_SALTI
Sequence: MTKRYFVTGTDTEVGKTVASCALLQAATQLGYQTVGYKPVASGSEMTTDGLRNSDALALQRNSSLPQPYSAINPYTFAEPTSPHIASADEGRAIDAAVLSRGLRTLEAQADWVLTEGAGGWFTPLSATLTFADWVQTEQLPVILVVGVKLGCINHAMLTALAVEQAGLPLVGWIANDMQPPGARHGEYLATLRRVIPAPLLGEIPWLGVSPSQAATGQYLDLSPLERA
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD 1, DTB synthetase 1, DTBS 1, Dethiobiotin synthase 1.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUF9_ARATH
Sequence: MFSPGTTVEVSSKINNKEVVWVPAVVIKEFKEDDEYKYIVRVYDKSFSCKGNKAARLNKTVDLCSLRPTPPSISVEEYQLKEYVEVFHDGMGWRQGRVMKIQERVMLSQGRVMVSQGRVMGNLSQKCYIVLLEATKKQISFKQSDLRPLQVWEDGVWKMLQTRESSLTQGSGDETSDSVRNANESDPPVTPRPGITTPPLKQIEAETQRKTLPRNQNASVNDSTRENENSEDINRKRKREESLCSDASVEDTTMTLPFEKKLSIWKTLESVETVPQSPHFSPLVETREDCREMSAVGMMLTFPCLLEEVKSLQHDNSISSLISLSNNFCELEKHGFNVKAPQSRISKLLSLRGKQSMKMDELKGAEKVTAEKESIKIENERKILELQRLNEEVDKEIAQSKSCAAKIVQQLEDVELQFQTTASAPW
What is the function of this protein?
May be involved in the polar growth of plant cells via transportation of RNAs.
What are the official names of this protein?
DUF724 domain-containing protein 9, AtDUF9.
Protein: BH120_ARATH
Sequence: MNPSNNPKKTRHQSHMPQERDETKKEKKLLHRNIERQRRQEMAILFASLRSQLPLKYIKGKRAMSDHVNGAVSFIKDTQTRIKDLSARRDELKREIGDPTSLTGSGSGSGSSRSEPASVMVQPCVSGFEVVVSSLASGLEAWPLSRVLEVLHGQGLEVISSLTARVNERLMYTIQVEVNSFDCFDLAWLQQKLIEQLVLSTTRH
What are the official names of this protein?
Transcription factor bHLH120, Basic helix-loop-helix protein 120, AtbHLH120, bHLH 120, Transcription factor EN 4, bHLH transcription factor bHLH120.
What are the subcellular locations of this protein?
Nucleus.