PharMolix/UniProtQA huggingface dataset:
Protein: EFTU_STAA9
Sequence: MAKEKFDRSKEHANIGTIGHVDHGKTTLTAAIATVLAKNGDSVAQSYDMIDNAPEEKERGITINTSHIEYQTDKRHYAHVDCPGHADYVKNMITGAAQMDGGILVVSAADGPMPQTREHILLSRNVGVPALVVFLNKVDMVDDEELLELVEMEVRDLLSEYDFPGDDVPVIAGSALKALEGDAQYEEKILELMEAVDTYIPTPERDSDKPFMMPVEDVFSITGRGTVATGRVERGQIKVGEEVEIIGLHDTSKTTVTGVEMFRKLLDYAEAGDNIGALLRGVAREDVQRGQVLAAPGSITPHTEFKAEVYVLSKDEGGRHTPFFSNYRPQFYFRTTDVTGVVHLPEGTEMVMPGDNVEMTVELIAPIAIEDGTRFSIREGGRTVGSGVVTEIIK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MADL2_BOVIN
Sequence: MGSTMEPPGGGYLHLGAVTSPVGTARVLQLVFGCTTFSLVAHRGGFSGVQGTFCVAAWGFCFALSVLVVACEFTRLHGCLRLSWGNFTAAFAMLATLLSATAAVIYPLYFTRLECPPEPEGCTARNFRLAASVFAGLLFLAYATEVALTRARPGQVASYMATVSGLLKIVQAFVACIIFGALVHDSRYGRYVATQWCVAVYSLCFLATVVVVILSVLGHTGGLGCPFDRMVVVYTFLAVLLYLSAAVIWPVFCFDPKYGEPGRPPDCPRGSCPWDSQLVVATFTYVNLLLYVADLAYSQRIRFVPTF
What are the official names of this protein?
Myeloid-associated differentiation marker-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the MAL family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TODD_PSEP1
Sequence: MRLEGEVALVTGGGAGLGRAIVDRYVAEGARVAVLDKSAAGLEALRKLHGDAIVGVEGDVRSLDSHREAVARCVEAFGKLDCLVGNAGVWDYLTQLVDIPDDLISEAFEEMFEVNVKGYILAAKAALPALYQSKGSAIFTVSNAGFYPGGGGVLYTAGKHAVIGLIKQLAHEWGPRIRVNGIAPGGILGSDLRGLKSLDLQDKSISTFPLDDMLKSVLPTGRAATAEEYAGAYVFFATRGDTVPLTGSVLNFDGGMGVRGLFEASLGAQLDKHFG
What are the official names of this protein?
Cis-toluene dihydrodiol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: HIS3_BURO1
Sequence: MNTETKSLPAWLDKVRWDDNGLVPVIAQEASTNDVLMFAWMNREALAKTIETQRAVYYSRSRKRLWFKGEESGHVQHVHEVRLDCDEDVVLLKVEQVSGIACHTGRHSCFFQKFEGTVDGGDWVAVEPVLKDPEHIYK
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
Protein: CBPM_ECO8A
Sequence: MANVTVTFTITEFCLHTGISEEELNEIVGLGVVEPREIQETTWVFDDHAAIVVQRAVRLRHELALDWPGIAVALTLMDDIAHLKQENRLLRQRLSRFVAHP
What is the function of this protein?
Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA.  Together with CbpA, modulates the activity of the DnaK chaperone system.  Does not inhibit the co-chaperone activity of DnaJ.
What are the official names of this protein?
Chaperone modulatory protein CbpM.
What is the protein family that this protein belongs to?
Belongs to the CbpM family.
Protein: SELH_HUMAN
Sequence: MAPRGRKRKAEAAVVAVAEKREKLANGGEGMEEATVVIEHCTSURVYGRNAAALSQALRLEAPELPVKVNPTKPRRGSFEVTLLRPDGSSAELWTGIKKGPPRKLKFPEPQEVVEELKKYLS
What is the function of this protein?
May be involved in a redox-related process.
What are the official names of this protein?
Selenoprotein H, SelH.
What is the protein family that this protein belongs to?
Belongs to the SelWTH family.
Protein: MURG_CLOBL
Sequence: MKKIIMTGGGTAGHVTPNLALVPELKKSGYEIKYIGSIEGIERKIIEKEGIEYFPISSGKLRRYFDLKNFSDPFKVLKGVFQAKKIIKREKPDIVFSKGGFVTVPVVIAAHLNKIPVIAHESDITPGLANKLATPYCTRVCVTFPESVKHIKGDKAVLTGTPIRRELLEGNKLEGIKLCGFKDNKPILLIIGGSLGSKIINEIVRKNLDNILSKFNIIHICGKSNLDENLENRKGYAQFEYVNEELPDLMKASDLVISRAGANVIYELLALKKPNLLIPLSKKSSRGDQILNAASFEKSGYSLVLKEEELEDKTLMKKLNYLYENRNVYINNMSKSKMDNGVKNITELIKKYTK
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NU1M_CANLU
Sequence: MFFINIISLIIPILLAVAFLTLVERKVLGYMQLRKGPNIVGPYGLLQPIADAVKLFTKEPLRPLTSSMSMFILAPILALSLALTMWIPLPMPYPLINMNLGVLFMLAMSSLAVYSILWSGWASNSKYALIGALRAVAQTISYEVTLAIILLSVLLMNGSFTLSTLIITQEHMWLIFPAWPLAMMWFISTLAETNRAPFDLTEGESELVSGFNVEYAAGPFALFFLAEYANIIMMNILTTILFFGAFHNPFMPELYSINFTMKTLLLTICFLWIRASYPRFRYDQLMHLLWKNFLPLTLALCMWHVALPIITASIPPQT
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GLNA_YARLI
Sequence: MVLSKYLDLPQHGAVLAEYIWIDAHFNIRSKCKTLDKKPTSIEDLPEWNFDGSSTDQAPGHDSDIYLRPAAIYPDPFRRGDNIIVLAECWNNDGTPNKFNHRHECAKLMSAHEKEVIWFGIEQEYTMFDESDNPVGWPKGGFPAPQGPYYCGVGTGKVFARDVVEAHYRACLYSGINISGINAEVMPSQWEYQVGPCEGISMADELWMSRYLLHRVAEEFGIKISFHPKPLQGDWNGAGCHTNVSTKSMREPGGMKHIEAAIEKLAARHKEHIAVYGEDNDMRLTGRHETGSIGSFSSGVANRGCSIRIPRSVAKEGYGYFEDRRPASNIDPYLVTGIMTETICGSIPDADMVEETKRGEEEGF
What are the official names of this protein?
Glutamine synthetase, GS, Glutamate--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIA_PSEPG
Sequence: MYLQLLKSLNRLHPRAWDFVQLSRMDRPIGIYLLLWPTLSAVWIAGNGSPTLANVLIFGLGVVLMRAAGCCINDFADRKVDGHVKRTADRPLASGRVRPREALALFAMLVGVSFLLVLCTNSRTVWLSFGAVALAFCYPFMKRYTYYPQVVLGAAYSWGIPMAFTAAGGELPASAWLLYIANLLWTVGYDTYYAMVDRDDDLKIGVKSTAILFGDADRNIILTLQLLSLGCLLLAGSRFDLGGWFHLGLLGAAACFAWEYWSTRKLDRESCFKAFLHNHWAGLLVFIGVVLDYAFR
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SHC1_HUMAN
Sequence: MDLLPPKPKYNPLRNESLSSLEEGASGSTPPEELPSPSASSLGPILPPLPGDDSPTTLCSFFPRMSNLRLANPAGGRPGSKGEPGRAADDGEGIVGAAMPDSGPLPLLQDMNKLSGGGGRRTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCEAVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDVISTIGQAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPLGGVVDMRLREGAAPGAARPTAPNAQTPSHLGATLPVGQPVGGDPEVRKQMPPPPPCPGRELFDDPSYVNVQNLDKARQAVGGAGPPNPAINGSAPRDLFDMKPFEDALRVPPPPQSVSMAEQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGVVRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVERKL
What is the function of this protein?
Signaling adapter that couples activated growth factor receptors to signaling pathways.  Participates in a signaling cascade initiated by activated KIT and KITLG/SCF.  Isoform p46Shc and isoform p52Shc, once phosphorylated, couple activated receptor tyrosine kinases to Ras via the recruitment of the GRB2/SOS complex and are implicated in the cytoplasmic propagation of mitogenic signals.  Isoform p46Shc and isoform p52Shc may thus function as initiators of the Ras signaling cascade in various non-neuronal systems.  Isoform p66Shc does not mediate Ras activation, but is involved in signal transduction pathways that regulate the cellular response to oxidative stress and life span.  Isoform p66Shc acts as a downstream target of the tumor suppressor p53 and is indispensable for the ability of stress-activated p53 to induce elevation of intracellular oxidants, cytochrome c release and apoptosis.  The expression of isoform p66Shc has been correlated with life span (By similarity).  Participates in signaling downstream of the angiopoietin receptor TEK/TIE2, and plays a role in the regulation of endothelial cell migration and sprouting angiogenesis.
What are the official names of this protein?
SHC-transforming protein 1, SHC-transforming protein 3, SHC-transforming protein A, Src homology 2 domain-containing-transforming protein C1, SH2 domain protein C1.
What are the subcellular locations of this protein?
Cytoplasm. SUBCELLULAR LOCATION: [Isoform p46Shc]: Mitochondrion matrix. Note=Localized to the mitochondria matrix. Targeting of isoform p46Shc to mitochondria is mediated by its first 32 amino acids, which behave as a bona fide mitochondrial targeting sequence. Isoform p52Shc and isoform p66Shc, that contain the same sequence but more internally located, display a different subcellular localization. SUBCELLULAR LOCATION: [Isoform p66Shc]: Mitochondrion. Note=In case of oxidative conditions, phosphorylation at 'Ser-36' of isoform p66Shc, leads to mitochondrial accumulation.
Protein: NUOA_GEOKA
Sequence: MSNIYANSYLIIFVFLCLGVLLPIGALTAGRWLRPHVPSDAKATTYESGNNPFHDSRVQFQVRYYLFALLFVIFDIETVFLYPWAVVYDQLGLFALVEMIIFIVLLAIGLIYAWKKKVLRWM
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DNAA_STRE4
Sequence: MTENEQIFWNRVLELAQSQLKQATYEFFVHDARLIKVDNHVATIFLDQMKELFWEKNLKDVILTAGFEVYNAQIAVDYVYEDDLMIEQQHQGQQGYTEQAFQQLPAVQSDLNPKYSFDNFIQGDENRWAVAASIAVANTPGTTYNPLFIWGGPGLGKTHLLNAIGNSVLLENPNARIKYITAENFINEFVVHIRLDTMDELKEKFRNLDLLLIDDIQSLAKKTLSGTQEEFFNTFNALHNNNKQIVLTSDRTPDHLNDLEDRLVTRFKWGLTVNITPPDFETRVAILTNKIQEYNFIFPQDTIEYLAGQFDSNVRDLEGALKDISLVANFKQIDTITVDIAAEAIRARKQDGPKMTVIPIEEIQAQVGKFYGVTVKEIKATKRTQDIVLARQVAMFLAREMTDNSLPKIGKEFGGRDHSTVLHAYNKIKNMIGQDESLRIEIETIKNKIK
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSH_SALTI
Sequence: MSNVPAELKYSKEHEWLRKEADGTYTVGITEHAQELLGDMVFVDLPEVGATVSAGDDCAVAESVKAASDIYAPVSGEIVAVNDALSDSPELVNSEPYAGGWIFKIKASDESELESLLDATAYEALLEDE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: TEX2_CATRO
Sequence: MEFVVSPFAFLIFFFILLKMIAKNFKNPKKNTKPLPPGPKKLPIIGNLHQLGGGLAHHILRDLSQNYGPLMHLKIGELSTIVISSTEMAKQVFKVHDIHFSNRPSHILVFKIVSYDYKDIVLSQYGNYWRELRKVCNLHLLSPNRVQSFRFIREDSVLNMMKSISSNEGKVVNLSEMILSLIYGITARAAFGVWSKRHEEFIRLESEIQRLATTFVLADMFPSIKILGALSGLRYKVEKVHKKVDEILEDILKEHRNNNISIEKEEEEEEENNGGKKDLVDVLLDIQKNGEMETPFTDQHIKAIIFDMFSAGTLTSTIAVDWAMAEMMKNPRVMKRAQEEVRNVYNGIGNVNESKLDELKYLQAIIKETLRIHPGTPIVHRETREECEINGYRIPAKARVMVNAWAISRDPNYWPDPDSFKPERFLGSEVDFKGTHFEYTPFGAGRRICPGISYAIANIQLPLAQLLYHFDWKLAGGMKPEELDMAEILGTAAQRKEDLLLIPNSHSCSSLKQQV
What is the function of this protein?
Component of the monoterpenoid indole alkaloids (MIAs, e. g.  echitovenine, tabersonine, lochnericine, 19-hydroxytabersonine and horhammericine) biosynthetic pathway; MIAs are used in cancer treatment and other medical applications (PubMed:31009114).  Cytochrome P450 catalyzing the conversion of tabersonine to lochnericine (PubMed:31009114, PubMed:29934299).
What are the official names of this protein?
Tabersonine 6,7-epoxidase isoform 2, Cytochrome P450 71D347.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: CCA_GEOKA
Sequence: MKPPFEQALGIIRQLKRHGYEAYFVGGAVRDLLIGRAIGDVDIATSALPEEVMRLFPKTIDVGSKHGTVVVVHEGTAYEVTTFRTDGDYEDHRRPESVTFVRSLEEDLKRRDFTMNAIAMDERGTIIDPFGGQEAIERRLICTVGAADERFREDALRMMRAVRFVSQLGFALSEDTKSAIVQNAPLMAHISVERMTMEMEKLLAGPFVAEALPLLADTGLFAYLPGLAAKVQLLRSAAAFRWPWLTKREERWALLCRALDVKDIRPFLRAWKLPNKVIDEAGAILAALDDVPRPEEWTNEQLFSAGLERALSVEAVRAALCGAPSEPHHEELRRRFAALPIKTKGELAVNGKDVIRWAGKPAGPWVKETLDAIWRAVVSSEVENEKERIYAWLMERNRTHEKNC
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
Protein: MTNA_HORVU
Sequence: MGESSALQSILYGRGALRLLDQRKLPLEEVYVDVKDSADGWNAIRDMVVRGAPAIAIAAALSLAVEVNDHNFIGTPAEAASFVSKKLEYLVSSRPTAVNLSDAATKLQNLVSTTAETAKDAKSIFQVFIEAAETMLVDDVADNKAIGLHGAEFLQRQLGSSKNISVLTHCNTGSLATAGYGTALGVIRALHSGGVLEKAFCTETRPFNQGSRLTAFELVHDKIPATLIADSAAAALMNNGQVQAVIVGADRIAANGDTANKIGTYNLSIAAKHHGVQFYVAAPVTSIDLSLPSGKQIVIEERSPKELLNSEGGLGKQVAASGISVWNPAFDVTPADLITAIITEKGVITKSDPDGTFDIKSFIECAK
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, Protein IRON DEFICIENCY INDUCIBLE 2, HvIDI2, S-methyl-5-thioribose-1-phosphate isomerase, Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DEST_CHICK
Sequence: MASGVQVADEVCRIFYDMKVRKCSTPEEVKKRKKAVIFCLSPDKKCIIVEEGKEILVGDVGVTVTDPFKHFVEMLPEKDCRYALYDASFETKESKKEELMFFLWAPEQAPLKSKMIYASSKDAIKKKFQGIKHECQANGPEDLNRACIAEKLGGSLVVAFEGSPV
What is the function of this protein?
Actin-depolymerizing protein.  Severs actin filaments (F-actin) and binds to actin monomers (G-actin).  Acts in a pH-independent manner.
What are the official names of this protein?
Destrin, Actin-depolymerizing factor, ADF.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family.
Protein: RPOA_STRPG
Sequence: MIEFEKPIITKIDENKDYGRFVIEPLERGYGTTLGNSLRRVLLSSLPGAAVTSIKIDGVLHEFDTIPGVREDVMQIILNVKGLAVKSYVEDEKIIELEVEGPAEVTAGDILTDSDIELVNPDHYLFTIAEGHSLRATMTVAKKRGYVPAEGNKKDDAPVGTLAVDSIYTPVKKVNYQVEPARVGSNDGFDKLTIEIMTNGTIIPEDALGLSARVLIEHLNLFTDLTEVAKATEVMKETEKVNDEKVLDRTIEELDLSVRSYNCLKRAGINTVFDLTEKSEPEMMKVRNLGRKSLEEVKVKLADLGLGLKNDK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: MDH_BACC1
Sequence: MTIKRKKVSVIGAGFTGATTAFLLAQKELADVVLVDIPQLENPTKGKALDMLEASPVQGFDANIIGTSDYADTADSDVVVITAGIARKPGMSRDDLVATNSKIMKSITRDIAKHSPNAIIVVLTNPVDAMTYSVFKEAGFPKERVIGQSGVLDTARFRTFIAQELNLSVKDITGFVLGGHGDDMVPLVRYSYAGGIPLETLIPKERLEAIVERTRKGGGEIVGLLGNGSAYYAPAASLVEMTEAILKDQRRVLPAIAYLEGEYGYSDLYLGVPVILGGNGIEKIIELELLADEKEALDRSVESVRNVMKVLV
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: TSAD_ECODH
Sequence: MRVLGIETSCDETGIAIYDDEKGLLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQAALKESGLTAKDIDAVAYTAGPGLVGALLVGATVGRSLAFAWDVPAIPVHHMEGHLLAPMLEDNPPEFPFVALLVSGGHTQLISVTGIGQYELLGESIDDAAGEAFDKTAKLLGLDYPGGPLLSKMAAQGTAGRFVFPRPMTDRPGLDFSFSGLKTFAANTIRDNGTDDQTRADIARAFEDAVVDTLMIKCKRALDQTGFKRLVMAGGVSANRTLRAKLAEMMKKRRGEVFYARPEFCTDNGAMIAYAGMVRFKAGATADLGVSVRPRWPLAELPAA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLU_SALCH
Sequence: MSEMTPREIVSELNKHIIGQDNAKRSVAIALRNRWRRMQLDEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAKNNWGQAEQQQEPSAARQTFRKKLREGQLDDKEIEINLAAAPMGVEIMAPPGMEEMTSQLQSMFQNLGGQKQKPRKLKIKDAMKLLVEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKRGETSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQVAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASVTVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNETTENIGARRLHTVLERLMEEISYNASDLHGQNITIDAEYVSKHLDALVADEDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Heat shock protein HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE_UREU1
Sequence: MKIRTRYAPSPTGYLHIGGARTALFNYLLAKAYDGDFIIRIEDTDVERNVEGGIDSQFNFLEWMGIVADESIRNPKTFGPYIQSQKLKHYEALALDLVAQKKAYFCFCSKERLDADRELAEKLHETPKYKRHCLNLNEQTIQANLLANKEYTIRLKIDENNEYSWDDLIRGKISIPGSALTDPVILKSNKIAMYNFAVVIDDYEMQISHVIRGEEHISNTPYQLAIAQALNYDLSKIKYGHLSIIVDETGKKLSKRNLALKQFVSDYEKDGYWPHAITNFVALLGWSPKNNQEIMSLVEMVENFDVNNLSKSPAFFDINKMNWFSTQYFNNISQDEFIDFVKTHPLTKELVLKDTTFIDKALLFKSHIVNLKQLINLVDEQFNSNKQLLEEDVNHIKNNQLTNVVQVFYEQLIVSEKFDEQSIKEVIKQVQKTTNNKGANLYMPIRIATTFSSHGPELAKTIYYLGRENVLKNLQSILKVLG
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPHN_DROPS
Sequence: MVLQGAKQRLCSSKNLDTCVLTPKYQTAYACEGKKLTIECEQGELINLIRANYGRFSITICNDHGNVEWSVNCMFPKSLTVLNSRCAHKNSCSVLAATSMFGDPCPGTHKYLEAHYQCVSAAQTSTTTNRPSPPPWVLNNGPPIFGNGSGLIHPTNIGGGSGGASAPPRLPTLPGVVGINGNGGMFNVPPPATHATPPGSTATLPGGRLKGVATSTTTTKHPAGRRDGLPPPPQLHHHHNHHTDETTPTKPSGKVPAASNATAPSNTRILTGVGGGGTDDGTLLTTKSSPNRTPGTAASGPSVSSNGSAVRTINNINLNAAGMAGADDETKLFCGPTHARNLFWNMTRVGDVNVQPCPGGAAGIAKWRCVLMKRMPDSSFDEDDEEMAGTSTTTPMSTSGDCLHNSSSCEPPVTMAHKVNQRLRNFEPTWHPLTPDLTQCRSLWLNNLEMRVNQRDSSLISIANDMSEVTSSKTLYGGDMLVTTKIIQTVSEKMLHDKETFPDQRQREAMIMELLHCVVKTGSNLLDESQLSSWLDLNPEDQMRVATSLLTGLEYNAFLLADTIIRERSVVQKVKNILLSVRVLETKTIQSSVVFPDSDQWPISSDRIELPRAALIENSEGGLVRIVFAAFDRLESILKPSYDHFDLKSSRSYVRNTAILTNDSDASAGDLQQRLRILNSKVISASLGKGRHIQLSQPITLTLKHLKTENVTNPTCVFWNYIDHAWSANGCSLESTNRTHSVCSCNHLTNFAILMDVVDEHQHSLFTMFDGNMRIFIYISIAICVVFIVIALLTLKLFNGVFVKSARTSIYINIYICLLAIELLFLLGIEQTETSIFCGFITVFLHCAILSGTSWFCYEAFHSYSTLTSDELLLEVDQTPKVNCYYLLSYGLSLSVVAISLVINPSTYTQNDYCVLMEANAVFYATFVAPVLIFFMAAIGYTFLSWIIMCRKSRTGLKTKEHTRLATVRFDIRCSFVFFLLLSAVWCSAYFYLRGAKMDEDVTGIYGYNFICFNTLLGLYIFVFHCIQNEKIRREYRKYVRQHAWLPKCLRCSKTSISSGIVAGGGTGLGGTNAGTLCSVSTAKKSKLPLGTNDDAHDEQQQQQHMSATEDAIMGASSDCELNEAQQRRTLKSGLITGTLQPSQSLGGHVVLERGNTLRSTGHASPTSSAGSTHLIFAHKQQQQQPPLGEAYYHQPDYYSWKQTAGGMKAQREYYNNAGAATSSPQQAHEVFYWTQKPNSQHGKKKRGGVGAIPASPSGSLHSRATAASQVLFYPSYKKTKPGQQAHPHYAEALDPPQPPNTAAYYQQQQQLRQQRQQQQQQLSSDEEQAEQHAHLLHLQHQQQQQQQRRAGGQQQLPAPPPHMAQYQQEFMQRQYRNKHSNCDLGDAYYNQGSVGGADGGPVYEEILSNRNSDAQHYEVGDFDVDEVYNNSVGTGVFNNMRAAVAAGGSRYGGSLSGGSVSSRNQQQQQHSLAQPISARRCTADEDDDEDEDDEETTAAEQLHDGVCDEEEEDEESDMEDDSHGLPPQSAERMRRLMALQDEDFKRRFQRQQRKHGAPVDYGTLPPGSAQAVIGGAHPEHNGAVFGVSGGVGEGSMRGALRQQHAKSPSARLAVNELFGHGNTGPPLPPANQTPAQKRQQLQKLSPQSTTSSSSHTSHSNPHSHPPHHQQRHLSAMLDENNTVRCYLEPLAK
What are the official names of this protein?
Latrophilin Cirl.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HACB_METTH
Sequence: MEGIIRGRVWRFGDNVDTDMIIPGRYLRTFSLDELASHVMEGARPEFASQVRKGDIIVAGRNFGCGSSREQAPVALKHAGVVAIIAESFARIFYRNAINIGLPVIMAKVDADDGDEVSIDLRSGQIRNLTAGSEYRMKPFNDYMLSILEDGGLVNHYLKTIDTGISGDEG
What is the function of this protein?
Component of a hydro-lyase with broad substrate specificity for cis-unsaturated tricarboxylic acids.  Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4-tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4-tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate).  Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis-homo(3)-aconitate.  These reactions are part of the biosynthesis pathway of coenzyme B.
What are the official names of this protein?
Methanogen homoaconitase small subunit, HACN, Homoaconitate hydratase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 2 subfamily.