PharMolix/UniProtQA huggingface dataset:
Protein: VSP1_CRODM
Sequence: VIGGDECNIN
What is the function of this protein?
Thrombin-like snake venom serine protease that coagulates human plasma and bovine fibrinogen by hydrolysis of the alpha chains (FGA) (minimum coagulation dose is 120 ug on fibrinogen).  Has fibrinogenolytic activities, and degrades preferentially the Aalpha chain (FGA).  Shows amidolytic activity toward N-benzoyl-L-Arg-p-nitroanilide, has a lower activity than Cdc SII.  In vivo, intravenous injection induces defibrin(ogen)ation and a loss of the righting reflex and opisthotoxins, together with a typical gyroxin-like effect (18-20 minutes).  Subcutaneous injection into the footpads induces moderate edema.  Potentiates local hemorrhagic activity induced by metalloproteinases (BaP1).
What are the official names of this protein?
Thrombin-like enzyme Cdc SI, SVTLE, Fibrinogen-clotting enzyme, Snake venom serine protease, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: 2ODD_SINHE
Sequence: MGSTAPLRLPVIDLSMKNLKPGTTSWNSVRTQVREALEEYGCFEAVIDAVSPELQKAVCNKGHELLNLPLETKMLNGNKPEYDGFTSIPNLNEGMGVGRITDLEKVERFTNLMWPEGNKDFCETVYSYGKRMAEVDHILKMMVFESFGMEKHFDSFCESTNYLLHFMRYQQPGKDGRSPALSLHKDKSILTIVNQNDVKGLEFETKDGEWILPTADNHIVLLGDCFMAWSNGRLHSPLHRVTLVANQARLSTSSFSFPKDIIETPAELVDEEHPLLFNPFEITELLAYCFTKEGAKAVCDLKQYKAYTGA
What is the function of this protein?
2-oxoglutarate-dependent dioxygenase involved in the biosynthesis of etoposide, a chemotherapeutic compound of the topoisomerase inhibitor family (PubMed:26359402).  Catalyzes the conversion of yatein to deoxypodophyllotoxin (PubMed:26359402).  Can also use, to some extent, demethylyatein as substrate (PubMed:26359402).
What are the official names of this protein?
Deoxypodophyllotoxin synthase, 2-oxoglutarate dependent dioxygenase.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: ENTA_ECOLI
Sequence: MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVVDGGSTLGA
What is the function of this protein?
Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine.  Catalyzes the reversible NAD-dependent oxidation of the C3-hydroxyl group of 2,3-dihydro-2,3-dihydroxybenzoate (2,3-diDHB), producing the transient intermediate 2-hydroxy-3-oxo-4,6-cyclohexadiene-1-carboxylate, which undergoes rapid aromatization to the final product, 2,3-dihydroxybenzoate (2,3-DHB).  Only the compounds with a C3-hydroxyl group such as methyl 2,3-dihydro-2,3-dihydroxybenzoate, methyl-3-hydroxy-1,4-cyclohexadiene-1-carboxylate, trans-3-hydroxy-2-cyclohexene-1-carboxylate, cis-3-hydroxy-4-cyclohexene-1-carboxylate, cis-3-hydroxycyclohexane-1-carboxylic acid are oxidized to the corresponding ketone products.  The stereospecificity of the C3 allylic alcohol group oxidation is 3R in a 1R,3R dihydro substrate.  It can also increase the DHB-AMP ligase activity of EntE by interaction EntE.
What are the official names of this protein?
2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase, DiDHB-DH, Trans-2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: PSD_PSEF5
Sequence: MKKRLFIISQYLLPHHLLSRLAGCIAECRVRWFKNAFTRWFAKQYQVDMSEAQVEDVTAYEHFNAFFTRALKDGARPLDPTPGAVLSPADGAVSQLGPIEHGRVFQAKGHSYSVLELLGGDPALAQPFMGGDFATIYLSPKDYHRVHMPLAGTLREMVYVPGRIFSVNQTTAENVPELFARNERVVCIFDTERGPMALVLVGAMIVASIETVWAGLVTPPKRELKTVRYDEAARAPIHLEKGAEMGRFKLGSTAIVLFGPDQVQWAQELAAGSPVRMGQGLGLGLPKA
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ATPG_ROSCS
Sequence: MPSTREIRRRIRSVKNLAQITRAMEMVSASKMRRAQRNVLATRPYADRLLDVMGELTGRAVGMRRGTLLEVRPVVKGVALIVVTPDRGLAGSLVANVLRRASRFILDEQEKKHTVEVLAIGKKGRDFMVRTRQNLVAEVTKLGDYPRLTDILGIATNVINGFLSGRYDEVYVLYSQFVNTLVQRPTIKRLLPIDPPHEPAERMVDYTYEPSQEEVLRALLPRFVEVQLYQAVLEAIASEHSARMVAMRNATDNAKELQRDLTLSYNKTRQANITKEVSEIASGAAALAEM
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MUTL_CLOPE
Sequence: MNRINILNADTANKIAAGEVVERPSSVVKELVENSLDAGAKNITIEIQNGGESLIKIIDDGSGVHPEDVEKAFNPHATSKIKDTYDIFSINTLGFRGEALPSIASIARVDFKSKTEDFDMGKELIISGGEKESLTDCSMNRGTQIEVRDLFFNVPARKKFLKTTARESALINDLVNRISLANPDVSFKLFNNNKKILNTYGNGKLIDVIRTIYGKSTAENLIYFEEHKDTASVYGFIGNDTLARASRNNQSLFVNKRYVKNRSLTVAVENAFRSFNVTGKFPFFVLFIDTYPELIDVNIHPTKSEIKFKDERFIFKVVFDAVHSAMREYVKDTFTLPEEEEKKFEALKEEVIQESLDKEISTLEKLKENINYKVSEDKKKEEIYSYNPSKDYEAKTEVNIPVDFLSKENQDESFSINNSLENNEFKEVSAKREISYDPILIKNELKDKVSESTSESLERSDYKCNKNEYGNSIEEIIYREAKFPKLRVIGQFNKTYILAEYDSTLYLIDQHAAHEKILFEKYSSDIAKKKVEIQPLMIPLVVTLPTEDYLYYDENKEIFEKAGFKISDFGDNSIRIEEVPYFLDKLNPTELITSMINNLKKMGTGETVEVKYNKIASMSCRAAVKANDVLSILEMENLIEDLRYINDPFHCPHGRPTIIKFTSYELDKKFKRIT
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: SUFS_SALHS
Sequence: MTFPVEKVRADFPILQREVNGLPLAYLDSAASAQKPNQVIDAESAFYRHGYAAVHRGIHTLSAQATESMENVRKQASRFINARSAEELVFVRGTTEGINLVANSWGTENIRAGDNIIISEMEHHANIVPWQMLCERKGAELRVIPLHPDGTLRLETLAALFDDRTRLLAITHVSNVLGTENPLPDMIALARQHGAKVLVDGAQAVMHHAVDVQALDCDFYVFSGHKLYGPTGIGILYVKEALLQEMPPWEGGGSMISTVSLTQGTTWAKAPWRFEAGTPNTGGIIGLGAAIDYVTSLGLDKIGDYEQMLMRYALEQLAQVPDITLYGPAQRLGVIAFNLGKHHAYDVGSFLDNYGIAVRTGHHCAMPLMAWYGVPAMCRASLAMYNTHEEVDRLVAGLTRIHRLLG
What is the function of this protein?
Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules.  Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation.  Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine.  Selenocysteine lyase activity is however unsure in vivo.
What are the official names of this protein?
Cysteine desulfurase, Selenocysteine beta-lyase, SCL, Selenocysteine lyase, Selenocysteine reductase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAM41_DANRE
Sequence: MSLPALQNSAVFYRRIINRFPQDFSLAFAYGSAVFRQTGSSQGHMVKNMLDFVFAVDDPVTWHTMNLIENRKHYSFLRFLGPKQISSIQSDYGAGVYFNTLVPAEDRLIKYGVISTDALIDDLLHWKTLYVAGRLHKPVRILLQSENGNLRSALLGNLKSAVIASFLMLPESFSEEELYLQIAGLSYSGDFRMVFGEDKSKVSNIVKDNMQHFRQLYNRILQECPQVVYKPQQGRLEVDKSPEGQFTQLMALPRTLQQQITRLVDRPGKNRDVEEILLQVAQDPDCGSVVQQGISSIVKSSSITQSAKGIATAGLVKTVSYSTKKLQKMWRGWRRKPA
What is the function of this protein?
Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
What are the official names of this protein?
Phosphatidate cytidylyltransferase, mitochondrial, CDP-diacylglycerol synthase, CDP-DAG synthase, Mitochondrial translocator assembly and maintenance protein 41 homolog, TAM41.
What is the protein family that this protein belongs to?
Belongs to the TAM41 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: MOAA_CHLTE
Sequence: MNRESAKQLVLTDRFGRTVDYVRIAVTSACNLRCTYCLKEDAPTQTQQLDVVETSKLIALLAGMGVRKIRFTGGEPLLHPSIPELVRIAKATPGIDTVCITTNGVLLDRQLDALVEAGLDGVNLSLDTLDREKFTSITRRDRFEQVSKALDRLLATPSLTVKLNTLMLRGINNDEIPAFVELTREHDLTVRFMELQPFDDHQIWRTGRFMGAERIRERLADAYPELEAITGHSTEHYSFSLPGHRGSIAIIPAFSRNFCSSCSKLRITADARLISCLYHHESIDLAPALKGEMNEVELKKRIIEAVQQKPKDGLKSSHDTAASSMSQIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: OST4_YEAST
Sequence: MISDEQLNSLAITFGIVMMTLIVIYHAVDSTMSPKN
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST4, Oligosaccharyl transferase subunit OST4, Oligosaccharyl transferase 4 kDa subunit, OTase 4 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the OST4 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type III membrane protein.
Protein: UBID_SHELP
Sequence: MSFKDLRSFIDHLEANGELKRIAHPVDPHLEMTEIADRVLRAKGPALLFENPVGKTMPVLANLFGTPKRVAMALGKEDPLALRDVGELLAFLKEPEPPRGFKDAISKIPMFKQALNMPPKTVRNAPCQEVVVSGDEVDLTKLPIQHCWPGDVAPLVTWGLTITKGPRQKRQNLGIYRQQLLGKNKLIMRWLDHRGGALDFKDFKEQHPGERYPVVVALGADPVTILGAVTPVPDAMSEYAFAGLLRGERTEVCKALSCDLEVPATSEIILEGYIEPGEMAEEGPYGDHTGYYNETDEFPVFTVTHVSHRRDAIYHSTYTGRPPDEPAMLGVALNEVFVPILRKQYPEIVDFYLPPEGCSYRMAVISIRKQYPGHAKRVMMGAWSFLRQFMYTKFIIIVDEDVNCRDWNDVIWAITTRMDPKRDTVMIDNTPIDYLDFASPVAGLGSKMGMDATNKWEGETDREWGTPIVMDEAVKQRIDAIWDDLGIDDAPTL
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: APT_CHLL3
Sequence: MPIKSRIRAIPDYPKKGIMFRDITTLIKDPVGFRLVIDNLTQRYLENGVDFDVIVGIEARGFIIGSALAYALGKGFVPVRKPGKLPADTVSQEYALEYGTDKIEIHIDALEKGARVLLVDDLLATGGTALAAAPLIEKVGGVVSEMAFIVNLPDIGGEEKILAKGYKVFSLTAFEGE
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_PSEAB
Sequence: MARVKRGVIARRRHKKILKLAKGYYGARSRVFRVAKQAVIKAGQYAYRDRRQRKRQFRALWIARINAGARQNGLSYSRLIAGLKKAAIEIDRKVLADLAVNEKAAFTAIVEKAKASLA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: RL3_RIPO1
Sequence: MAVGILGTKLGMTQIFDQETGMAIPVTVVQAGPCTVTQVKTPDTDGYTAIQVGYHEVKEKALTKAEIGHLKKIDAPPLRHLKEYRLDDSSQYQLGDAIKADIFNPGDLVDVSGKSMGRGFAGYQKRHNFKRGNMTHGSKNHRLPGSTGAGTTPGRVYPGKRMAGQYGATQVTIRHLTVVRVDSDRNLILVKGAIPGKPGTLLNITPAKTVGK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: YQIR_BACSU
Sequence: MQKVLIVGAGKRGTALLHILIKTAIIDIIAVVDKDPEAPGLKEAEQYGIAVSSDWKPYIQQKPDIVIHTTGDQAVFDELLQRKHEDTIVMPGKMAYIVFQLMEEKQHLIQMLKEQTYKYDRIFNSTHDGMIFIDINEEIILFNHMAEKMVGKKREEVIGRPIKEVIPSTKMPRILKTRVPEYNQKQLLGDHLQIVTTRLPIIDEGGRLLGALCVFKDITDAVELAEEVTNLKQVRTMLEAIIQSSDEAISVVDENGIGLLINKAYTKMTGLSEKEVIGKPANTDISEGESMHLKVLETRRPVRGVRMKVGPNEKEVIVNVAPVIVDGILKGSVGVIHDVSEIKMLTAELNRARQIIRTLEAKYTFDDIIGKSEQMLVALEQAKLGAKTPATILLRGESGTGKELFAHAIHNESDRKYNKFIRVNCAALSENLLESELFGYEDGAFSGAKRGGKKGLFEEANNGSIFLDEIGELTQNMQAKLLRVLQEKEIVRVGGTKAIPVNVRVIAATNVNIEKAMADGTFREDLYYRINRYPISIPPLRQRLEDIEALSVRLIQKINRDYGRNVKGLSQQALRALSAYHWPGNVRELENVLGRAMIFLNPHMEWIEKDHLPVFELEQKENDTDQGTGFDFPDIEGEKLSVAVEKFEAHLIQQTLEKHHFNRTKTAKALGVSIRNLYYKMDKYGLANEGMQ
What are the official names of this protein?
Putative sigma L-dependent transcriptional regulator YqiR.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: MZM1_YARLI
Sequence: MSQGLTAYRNVLRAANLAFKNDHFVLGQAKANIRKGFEDGRKLDPKDEDVKVRLEHINGVAYVLRTQVVQGQKHNPDEEKYQLNLHKDSEMGDNESIKSPPPMPTKGKKGKKVKCCSE
What is the function of this protein?
Assembly factor required for Rieske Fe-S protein RIP1 incorporation into the cytochrome b-c1 (CIII) complex.  Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane.  Modulates the mitochondrial matrix zinc pool (By similarity).
What are the official names of this protein?
Mitochondrial zinc maintenance protein 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family. MZM1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: DEM_PHAJA
Sequence: YAFGYPS
What is the function of this protein?
Has a very potent opiate-like activity.  It has high affinity and selectivity for mu-type opioid receptors (By similarity).
What are the official names of this protein?
Dermorphin.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Dermorphin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: AUSR_EMENI
Sequence: MIIFNISALGPPKPMLQFVGRELVETSRATMLRLPIDSAMHPFSTLPNHELGLYIMWMMSAVFVIFKLLAPAKCDIPTVNGRRRFEIGQYQARRRFSVDGRGIILNGLQMARVFRVVSQKGPKIILGPEYANEVKSHPACNADVFIAKEFHAHVSGFEVLRPQQVMKDAIRLRLTRSIGALMKPISAETALILESQWGNSNCWHELDLNFTIASLVSRVSAVMFVGEELGRDQKWLSIVTNYSSDMFVADLDLCKWPEALRPIATYFLPSCGKLRRHIREAALMLYPILSEGYSAHQNKQNFLDWLEEIAGDRKYNPVLAQLSLAAAAIDTTSDLIIKTLTDICRFRDSQKLQEDLREEMVRVLRADGWEKSAMYNLKLLDSVLKETQRVKPVVVFGMGRYVTEQITLHDGTVISKGETINVVNTRIWDPAVYPNPLEWDPYRFVRRRDSGDHAAHLVSPTPDHMGFGLGKHSCPGRFFAATKIKIILCHILLKYDVKIPDEEISTVISSGNFLFPDSTLRISVRRRQDNLTIWD
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster B that mediates the biosynthesis of austinol and dehydroaustinol, two fungal meroterpenoids (PubMed:22329759).  The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid by the polyketide synthase ausA (PubMed:22329759).  3,5-dimethylorsellinic acid is then prenylated by the polyprenyl transferase ausN (PubMed:22329759).  Further epoxidation by the FAD-dependent monooxygenase ausM and cyclization by the probable terpene cyclase ausL lead to the formation of protoaustinoid A (PubMed:22329759).  Protoaustinoid A is then oxidized to spiro-lactone preaustinoid A3 by the combined action of the FAD-binding monooxygenases ausB and ausC, and the dioxygenase ausE (PubMed:22329759, PubMed:23865690).  Acid-catalyzed keto-rearrangement and ring contraction of the tetraketide portion of preaustinoid A3 by ausJ lead to the formation of preaustinoid A4 (PubMed:22329759).  The aldo-keto reductase ausK, with the help of ausH, is involved in the next step by transforming preaustinoid A4 into isoaustinone which is in turn hydroxylated by the P450 monooxygenase ausI to form austinolide (PubMed:22329759).  Finally, the cytochrome P450 monooxygenase ausG modifies austinolide to austinol (PubMed:22329759).  Austinol can be further modified to dehydroaustinol which forms a diffusible complex with diorcinol that initiates conidiation (PubMed:22234162, PubMed:22329759).  Due to genetic rearrangements of the clusters and the subsequent loss of some enzymes, the end products of the Emericella nidulans austinoid biosynthesis clusters are austinol and dehydroaustinol, even if additional enzymes, such as the O-acetyltransferase ausQ and the cytochrome P450 monooxygenase ausR are still functional (PubMed:29076725).
What are the official names of this protein?
Cytochrome P450 monooxygenase ausR, Austinoid biosynthesis clusters protein R.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: IGHG_RABIT
Sequence: GQPKAPSVFPLAPCCGDTPSSTVTLGCLVKGYLPEPVTVTWNSGTLTNGVRTFPSVRQSSGLYSLSSVVSVTSSSQPVTCNVAHPATNTKVDKTVAPSTCSKPTCPPPELLGGPSVFIFPPKPKDTLMISRTPEVTCVVVDVSQDDPEVQFTWYINNEQVRTARPPLREQQFNSTIRVVSTLPITHQDWLRGKEFKCKVHNKALPAPIEKTISKARGQPLEPKVYTMGPPREELSSRSVSLTCMINGFYPSDISVEWEKNGKAEDNYKTTPAVLDSDGSYFLYNKLSVPTSEWQRGDVFTCSVMHEALHNHYTQKSISRSPGK
What are the official names of this protein?
Ig gamma chain C region.
Protein: SUCC_BURM7
Sequence: MKIHEYQGKEILRKFGVAVPRGKPAFSVDEAVKVAQELGGPVWVVKAQIHAGGRGKGGGVKVAKSLEQVREYSNQILGMQLKTHQTGPEGQKVNRLLIEEGADIKKELYVGIVIDRVSQKVVVMASSEGGMDIEEVAEKTPEAIHKVAVEPSVGLQDAEADDLAKKIGVPDASIPQAREILKGLYKSFWETDASLAEINPLVLTGDGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDPAEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKLMLKNPGLKAILVNIFGGIMRCDVIAEGVIAGSKAVNLNVPLVVRMKGTNEDLGKKMLAESGLPIISADSMEEAAQKVVAAAAGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: DPO3_STRPM
Sequence: MSDLFAKLMDQIEMPLDMRRSSAFSSADIIEVKVHSVSRLWEFHFAFAAVLPIATYRELHDRLIRTFEAADIKVTFDIQAAQVDYSDDLLQAYYQEAFEHAPCNSASFKSSFSKLKVTYEDDKLIIAAPGFVNNDHFRNSHLPNLVKQFEAFGFGTLTIDMVSDQEMTEHLTKDFVSSRQALVKKAVQDNLEAQKSLEAMMPPVEEATPAPKFDYKERAAKRQAGFEKATITPMIEIETEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSFALQKWAKDDEELRKFDMIAKGAWLRVQGNIETNPFTKSLTMNVQQVKEIVHHDRKDLMPEGQKRVELHAHTNMSTMDALPTVESLIDTAAKWGHKAVAITDHANVQSFPHGYHRARKAGIKAIFGLEANIVEDKVPISYDPVDMDLHEATYVVFDVETTGLSAMNNDLIQIAASKMFKGNIVEQFDEFIDPGHPLSAFTTELTGITDKHLQDAKPLVTVLKAFQDFCKDSILVAHNASFDVGFMNANYERHDLPKITQPVIDTLEFARNLYPEYKRHGLGPLTKRFQVSLDHHHMANYDAEATGRLLFIFLRDAREKHGIKNLLQLNTDLVAEDSYKKARIKHATIYVQNQVGLKNMFKLVSLSNIKYFEGVPRIPRTVLDAHREGLLLGTACSDGEVFDAVLTKGIDAAVDLAKYYDFIEIMPPAIYQPLVVRELIKDQAGIEQVIRDLIEVGKRANKPVLATGNVHYLEPEEEIYREIIVRSLGQGAMINRTIGRGEGAQPAPLPKAHFRTTNEMLDEFAFLGKDLAYQVVVENTQDFADRIEEVEVVKGDLYTPYIDKAEETVAELTYQKAFEIYGNPLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMIGITEVNPMPPHYVCPSCQHSEFITDGSVGSGYDLPNKPCPKCGTPYQKDGQDIPFETFLGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGDEYAFRAGTVGTVAEKTAYGFVKGYERDYGKFYRDAEVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTASWQTTHFNFHDIDENVLKLDILGHDDPTMIRKLQDLSGIDPITIPADDPGVMALFSGTEILGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNAQDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIDAMRENNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIRAKAFELKTMSGGLDAVKARMEDITIKRKNNEATNVENDLFTTLEIVNEMLERGFKFGKLDLYKSDAIEFQIKGDTLIPPFIALEGLGENVAKQIVKARQEGEFLSKMELRKRGGASSTLVEKMDEMGILGNMPEDNQLSLFDDFF
What is the function of this protein?
Required for replicative DNA synthesis.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.
What are the official names of this protein?
DNA polymerase III PolC-type, PolIII.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. PolC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAMP1_MOUSE
Sequence: MAPGLRGLPRCGLWLLLAHHLFMVTACRDPDYGTLIQELCLSRFKENMETIGKTLWCDWGKTIQSYGELTYCTKHVAHTIGCFWPNPEVDRFFIAVHHRYFSKCPISGRALRDPPNSILCPFIALPITVTLLMTALVVWRSKRTEGIV
What is the function of this protein?
Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane.  Acts as a receptor for calcitonin-gene-related peptide (CGRP) together with CALCRL.
What are the official names of this protein?
Receptor activity-modifying protein 1.
What is the protein family that this protein belongs to?
Belongs to the RAMP family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: EIF3I_PUCGT
Sequence: MRPILLSGHERSLTQVKYNREGDLLFSCSKDHIINVWFTHNGERLGTYNGHNGTVWSVDVDSKSEFMVSGSADNSMRLWKVSTGECLKAWEFPTAIKRVSWSEDDTKIALVTEQRMGHQGAVRVFEINRDGGPQPDEPLLVFNPIGSKAQVVAFSSLDKHLITGHENGKVALWDVNTGEEVASKEKNHIGLITDLQMSADRTYFVTSSKDKSARLYDSRTLEVIKSYQDPQTPLNSAALIPGKPYLLMGGGQEAMAVTTTSARQGHFEIRMWHVVFEEEVSRIKGGFGPCNSIAVHPEGKGYAIGGEDGYVRLHHFDENTFRAKPYGHETEPKELD
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit I, eIF3i, Eukaryotic translation initiation factor 3 39 kDa subunit homolog, eIF-3 39 kDa subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit I family.
What are the subcellular locations of this protein?
Cytoplasm.