PharMolix/UniProtQA huggingface dataset:
Protein: PYRI_PYRNV
Sequence: MSKELMVSKIERGTVIDHIPAGRALAVLRVLGITGREGVRVALVMNVESKKLGRKDIVKIEGRELTPEEVNIISAVAPTATINIVRDYTVVRKFKVSPPEVVKGRFRCKNPTCITNAPREPVEPTFLLVRREPPLFVCTYCGRYHELGDLL
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: Y816_RICTY
Sequence: MKKLLLIAATSATILSSSISFAECMDNEWYLRVDAGVAMFNKEKDKTIGVKLKSNKAMPIDLGIGYYIAENVRADLTLGTTIGGKLKKSGAATNAHFTGTNVLVSHKPIVTRLLINGYVDLTSFDMFDIFVGAGVGPALVKEKISGASGLASNTTNTKNKTNVSYKLIFGTAAQVADGVKVELAYSWIDDGRTKSKHVIHEGASVQTGGMRYQSHNITVGLRFGI
What are the official names of this protein?
Putative adhesin RT0816.
Protein: CAZA2_CANLF
Sequence: MADLEEQLSDEEKVRIAAKFIIHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNLDQFTPVKIEGYEDQVLITEHGDLGNGKFLDPKNRICFKFDHLRKEATDPRPYEAENAVESWRTSVETALRAYVKEHYPNGVCTVYGKKIDGQQTIIACIESHQFQAKNFWNGRWRSEWKFTITPSTTQVVGILKIQVHYYEDGNVQLVSHKDIQDSLTVSNEVQTAKEFIKIVEAAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGKEMQNA
What is the function of this protein?
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends.  Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity).
What are the official names of this protein?
F-actin-capping protein subunit alpha-2, CapZ alpha-2.
What is the protein family that this protein belongs to?
Belongs to the F-actin-capping protein alpha subunit family.
Protein: THRH_PSEAE
Sequence: MEIACLDLEGVLVPEIWIAFAEKTGIDALKATTRDIPDYDVLMKQRLRILDEHGLKLGDIQEVIATLKPLEGAVEFVDWLRERFQVVILSDTFYEFSQPLMRQLGFPTLLCHKLEIDDSDRVVGYQLRQKDPKRQSVIAFKSLYYRVIAAGDSYNDTTMLSEAHAGILFHAPENVIREFPQFPAVHTYEDLKREFLKASSRSLSL
What is the function of this protein?
Phosphoserine phosphatase that mediates dephosphorylation of phosphoserine in the serine biosynthesis pathway.  Also able to dephosphorylate other substrates such as phospho-L(or D)-threonine, with lower activity.  Shows phosphoserine:homoserine phosphotransferase activity by transferring the phosphoryl group to homoserine using phosphoserine as the phosphoryl group donor.
What are the official names of this protein?
Phosphoserine phosphatase ThrH, PSP, PSPase.
What is the protein family that this protein belongs to?
Belongs to the thrH family.
Protein: OBG_VIBHA
Sequence: MKFVDEAVVKVQAGDGGSGVVSFWREKFITKGGPDGGDGGDGGDVYIQADENLNTLIDYRFQRFYEAERGENGRGGNCTGKRGKDITLRVPVGTRAVDIHTNEIVAEVAEHGKKVMVAKGGWHGLGNTRFKSSVNRAPRQRTLGTKGEIREIRLELLLLADVGMLGLPNAGKSTFIRAVSAAKPKVADYPFTTLIPSLGVVSVVPEKSFVVADIPGLIEGAADGAGLGIRFLKHLERCRVLLHMIDIMPIDQSDPIQNALTIIDELEQYSEKLAGKPRWLVFNKTDLMPEEEANEKIQEILDALGWEDEYFKISAINRNGTKELCYKLADFMENLPREEEEVAEEDKVNFMWDDYHKDAIAGKDVITEEDDDDWDDCDDEDDDGHVVYVRD
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg/CgtA, CgtA, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSBA_FRATT
Sequence: MANMIDKIDLKSQGSSNLSGEMTNHQKVGTLYKRLLLQVKHLWHFLLLAAIGSIFFSAADASMIYLINPILNYGFGPGGGITKQSATILMLMGVGMVGLLALRSVGSFVSQYFIGSLGQKVVYKFRKDIYKRLMDLPASFFDKHSTGQIISRLLYNVDQVIEATSTAIITVVQDGTFVIGLIVVMFVSSWQLSLFLIVVGPFLGLFISIINKKFRNLSRNTQSSMGNVTHTAEETIRNYKEIRIFGAQQKQQNKFFKNLDYTYSQQIRTIALDALTSPVIQIIASLVLAFSLFTIAIFGTNEGDGSSWLTAGSFASFFAAAAAILKPIKNLTKVNVVIQKAVAATEDIFYILDYPAEKETGSKELAKVDGNVTIKDLSFAFGEHKVLSGVSVDIKAGQTVAFVGKSGSGKTTLTSIISRFYTQHEGEILLDGVDTRELTLENLRSHLSIVSQNVHLFDDTVYNNIAFGLSREVSEEEVIDALKRANAYEFVQELSDGINTNIGNNGSKLSGGQRQRISIARALLKNAPVLIFDEATSALDNESERVVQQALESLTKSCTTIVIAHRLSTVENADKIVVMDGGRVVESGKHQELLEQGGLYTRLYQSGLQ
What is the function of this protein?
Involved in lipopolysaccharide (LPS) biosynthesis.  Translocates lipid A-core from the inner to the outer leaflet of the inner membrane.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
What are the official names of this protein?
ATP-dependent lipid A-core flippase, Lipid A export ATP-binding/permease protein MsbA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HUTP_BACHK
Sequence: MLLQGTHRIGRMAMLLALADENESPVLSIPKGWKYCTGKVGSMNSQKVVAAMETAAKSNQVIETDVYRETHALYHAIMEALYGVTRGQIQLADVLRTVGLRFAIVRGTPYDGKKEGEWVAVALYGTIGAPVKGSEHEAIGLGINHI
What is the function of this protein?
Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.
What are the official names of this protein?
Hut operon positive regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the HutP family.
Protein: TGT_XANC5
Sequence: MSRLQFQLQATDGHARRGRLTFPRGTVETPAFMPVGTYGSVKGILPEQIRALGAEIILGNTFHLYLRPGLEVIGDHGGLHGFARWDGPILTDSGGFQVFSLAHRRKITEQGVTFSSPTDGARVFLGPEESMKIQKVLDSDIVMIFDECTPYPATEDVARRSMELSLRWAQRSRDAHDGLGNDAALFGIVQGGVHPDLRSRSLDGLQGIGFDGYAIGGLAVGEPEHERNAMLEHLHPRLPAERPRYLMGVGRPEDLVEGVARGVDMFDCVMPTRNARNGHYFTSFGTVRIRNAKYERDLDTIEPGCGCHACSSGYTRAYLRHLDRCNEMLAPMLGTLHNLCYYEKLMADMRAAIASGTFVEFRRSFYAARGATTPPLPGETS
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: TMCAL_EXISA
Sequence: MQKTAIIAEYNPFHNGHYYQAQTARHETGADVMIAIMSAQFTQRGEPASFDKWKRAKAAVESGAIDLVIELPTQYGVQRADRFASASVSIAEQLRCQTLSFGSESGDIDAILHAARSHVEETPRYKEALKKALQEGHSSAQASSRAFRTVYPSFDLTRPNNILGYHYAKAAKSIQLHTVKRLGADYHDPSLMDVMSATGIRAHYLDIGEVRAVPASTEAMFRTRPMTHWEHYWPVLQFKLRTLPLHTMMELVGIDASLAPRLKQAGVEPSFERALAAVSTRRYTRTAIQRAFVAVLLHWLKDEAPTRFDEVPYVRPLAFNDLGRLALRDVKDDVPLVSKFDARLDFEARVTEAYRLPLQDDALIEHRQRPQFISSK
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y299_AERS4
Sequence: MEQVNKSTFSDVLEYVRMSRRQNKLKREIADNEKKIRDNQKRVLLLDNLSDYIKPGMSIDEVQAIIANMRTDYEERVDDHIIKNAELSKERKDLSAKLKAMSSSK
What are the official names of this protein?
UPF0265 protein ASA_0299.
What is the protein family that this protein belongs to?
Belongs to the UPF0265 family.
Protein: SELD_PHOLL
Sequence: MSTEVRLTQYSHGAGCGCKISPKVLETILHSEQEKFLDPHLLVGNETRDDAAVYDIGNGTGIISTTDFFMPIVDDPFDFGRIAATNAISDIYAMGGKPIMAIAILGWPIDKLAPEIARKVIEGGRAACKEAGIVLAGGHSIDAPEPIFGLAVTGIVNIDRVKQNSAAKVGSQLFLTKPLGIGVLTTAEKKGLLLPEHQGIAIETMCRLNKLGMDFAEVAGITAMTDVTGFGLLGHLSEICAGSGVQATLHFAKVPKLPEVESYIAKGCVPGGTGRNFDSYGHLIGEMTELQRKLLCDPQTSGGLLLAVLPEAMDEVKAIARCHGIELTAIGELSEQQSGRVLIEVNE
What is the function of this protein?
Synthesizes selenophosphate from selenide and ATP.
What are the official names of this protein?
Selenide, water dikinase, Selenium donor protein, Selenophosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the selenophosphate synthase 1 family. Class I subfamily.
Protein: ERA_ECOL5
Sequence: MSIDKSYCGFIAIVGRPNVGKSTLLNKLLGQKISITSRKAQTTRHRIVGIHTEGAYQAIYVDTPGLHMEEKRAINRLMNKAASSSIGDVELVIFVVEGTRWTPDDEMVLNKLRDGKAPVILAVNKVDNVQEKADLLPHLQFLASQMNFLDIVPISAETGLNVDTIAAIVRKHLPEATHHFPEDYITDRSQRFMASEIIREKLMRFLGAELPYSVTVEIERFVSNERGGYDINGLILVEREGQKKMVIGNKGAKIKTIGIEARKDMQEMFEAPVHLELWVKVKSGWADDERALRSLGYVDDL
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: TRY5_MOUSE
Sequence: MNSLLFLALVGAAVAFPVDDDDKIVGGYTCRENSIPYQVSLNSGYHFCGGSLINDQWVVSAAHCYKTRIQVRLGEHNINVLEGNEQFVNSAKIIKHPNFNSRTLNNDIMLIKLASPVTLNARVATVALPSSCAPAGTQCLISGWGNTLSFGVNNPDLLQCLDAPLLPQADCEASYPGKITNNMICVGFLEGGKDSCQGDSGGPVVCNGQLQGIVSWGYGCALKDNPGVYTKVCNYVDWIQDTIAAN
What is the function of this protein?
Serine protease capable of autoactivation.
What are the official names of this protein?
Trypsin-5, Testicular-specific serine protease 4, Trypsinogen 9, T9.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
Protein: FMT_LEVBA
Sequence: MTSVIFMGTPQFSAPILSSLIDNGYDVLAVVTQPDRRVGRKHVLTASPVKQVAVAHDIEVLQPEKISGSSEMARAIELAPDLIVTAAFGQFLPTKLLKAAKVAAVNVHASLLPKYRGGAPVHYAIMNGDSETGVSIMFMEKKMDAGAVLAQRAIPITDQDDVGTMFAKLSDLGRDLLLETLPKLLAGELTPVPQDESQVSFSPTIKPEEERVDINLSARMIDCKVRALRPFPTAHIYLNGVRTKLWHVTVLDQKTDLQPGAVVSRDKHHLAIATGEQGVLSLDELQPAGKPKLSITDYLNGTTDALTVGEQVAE
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: ATPL_RICCN
Sequence: MDMVSLKFIGTGLMAIGMYGAALGVSNIFSSLLSSIARNPSATENLQRMALIGAGLAEAMGLFSFVIAMLLIFS
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: OREX_HUMAN
Sequence: MNLPSTKVSWAAVTLLLLLLLLPPALLSSGAAAQPLPDCCRQKTCSCRLYELLHGAGNHAAGILTLGKRRSGPPGLQGRLQRLLQASGNHAAGILTMGRRAGAEPAPRPCLGRRCSAPAAASVAPGGQSGI
What is the function of this protein?
Binds to orexin receptor HCRTR2/OX2R only (By similarity).  Stimulates food intake (By similarity).  Modulates pituitary luteinizing hormone secretion in an ovarian steroid-dependent manner (By similarity).
What are the official names of this protein?
Hypocretin neuropeptide precursor, Hypocretin, Hcrt, Orexin precursor, Prepro-orexin, Preprohypocretin.
What is the protein family that this protein belongs to?
Belongs to the orexin family.
What are the subcellular locations of this protein?
Rough endoplasmic reticulum. Cytoplasmic vesicle. Synapse. Note=Associated with perikaryal rough endoplasmic reticulum as well as cytoplasmic large granular vesicles at synapses.
Protein: FADI_ECO57
Sequence: MGQVLPLVTRQGDRIAIVSGLRTPFARQATAFHGIPAVDLGKMVVGELLARSEIPAEVIEQLVFGQVVQMPEAPNIAREIVLGTGMNVHTDAYSVSRACATSFQAVANVVESLMAGTIRAGIAGGADSSSVLPIGVSKKLARVLVDVNKARTMSQRLKLFSRLRLRDLMPVPPAVAEYSTGLRMGDTAEQMAKTYGITREQQDALAHRSHQRAAQAWSDGKLKEEVMTAFIPPYKQLLAEDNNIRGNSSLADFAKLRPAFDRKHGTVTAANSTPLTDGAAAVILMTESRAKELGLVPLGYLRSYAFTAIDVWQDMLLGPAWSTPLALERAGLTMADLTLIDMHEAFAAQTLANIQLLGSERFAREALGRAHATGEVDDSKFNVLGGSIAYGHPFAATGARMITQTLHELRRRGGGFGLVTACAAGGLGAAMVLEAE
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, ACSs, Acetyl-CoA acyltransferase, Acyl-CoA ligase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPK1_ECO57
Sequence: MGQEKLYIEKELSWLSFNERVLQEAADKSNPLIERMRFLGIYSNNLDEFYKVRFAELKRRIIISEEQGSNSHSRHLLGKIQSRVLKADQEFDGLYNELLLEMARNQIFLINERQLSVNQQNWLRHYFKQYLRQHITPILINPDTDLVQFLKDDYTYLAVEIIRGDTIRYALLEIPSDKVPRFVNLPPEAPRRRKPMILLDNILRYCLDDIFKGFFDYDALNAYSMKMTRDAEYDLVHEMEASLMELMSSSLKQRLTAEPVRFVYQRDMPNALVEVLREKLTISRYDSIVPGGRYHNFKDFINFPNVGKANLVNKPLPRLRHIWFDKAQFRNGFDAIRERDVLLYYPYHTFEHVLELLRQASFDPSVLAIKINIYRVAKDSRIIDSMIHAAHNGKKVTVVVELQARFDEEANIHWAKRLTEAGVHVIFSAPGLKIHAKLFLISRKENGEVVRYAHIGTGNFNEKTARLYTDYSLLTADARITNEVRRVFNFIENPYRPVTFDYLMVSPQNSRRLLYEMVDREIANAQQGLPSGITLKLNNLVDKGLVDRLYAASSSGVPVNLLVRGMCSLIPNLEGISDNIRAISIVDRYLEHDRVYIFENGGDKKVYLSSADWMTRNIDYRIEVATPLLDPRLKQRVLDIIDILFSDTVKARYIDKELSNRYVPRGNRRKVRAQLAIYDYIKSLEQPE
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).
What are the official names of this protein?
Polyphosphate kinase, ATP-polyphosphate phosphotransferase, Polyphosphoric acid kinase.
What is the protein family that this protein belongs to?
Belongs to the polyphosphate kinase 1 (PPK1) family.
Protein: GSPC_PECCC
Sequence: MARLQAFKDPSFHSLVATFRSLPLIRRFVLGLILLLICQQLAVLTWRFLLPEDSRIVGVSVTPAQAKEKPATPGDFTLFGHAPDADASTVNDAALSGDIPLTSLNISLTGVLASGDAKRSIAIIAKDSQQYSRNVGDAIPGYEAKIVTISADRVVLQYQGRYEALHLYQEEEATGAPSSSGAFNQVKDEIQKDPFSAQDYLTISPVTEEEVLKGYQLNPGKNPDLFYRAGLQDNDLAVSLNGMDLRDADQAQQAMAQLAGMSKFNLTVERDGQQQDIYLALDGDH
What is the function of this protein?
Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.  Required for the translocation of the multiple pectic enzymes.
What are the official names of this protein?
Type II secretion system protein C, T2SS protein C, General secretion pathway protein C, Pectic enzymes secretion protein OutC.
What is the protein family that this protein belongs to?
Belongs to the GSP C family.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: MURG_HALHL
Sequence: MSVRTVAIAAGGTGGHVYPGLAVADALRERGHRVVWLGTRAGLEGRVVPAAGLDAEWLEIGGMRGKGLATIAALPWRLGRAVAVAGAALRRQRPDVVLGMGGYVAGPVGLAARLAGRPLIIHEQNARAGMTNRFLARLGHRVLTGFPDALGARSEWVGNPIRTRIHRLESPQERYARREGAPRVLVLGGSQGARALNRYVPQALSAIGGGQPQVLHQAGELTLEEARTEYGRAGLDGAEVVPFIEDMAGAYAWADLVVARSGALTVAELAAAGVPAVLVPLPWAVDDHQTANAEWLCAAGAARRLLQPDLEQGALGPVLAELLGDRRRLAEMGEAARGVARPDATDRVATICEEVAHG
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: S22A7_PIG
Sequence: MAFEELLDKVGGFGPFQLWNVALLALPRVLLPMHFLLPIFLTAVPAHRCALPGAPANFSHQDAWLEAHLPREPDGRFSSCLRFTHSRALPNTTLWGLGQSPGEQLEGEPSTVPCPQGWEYDHSEFSSTIATEWDLVCEQKGLNRATSTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYVSALVLGLVSAASVSYTMFAITRTLTGTALAGFTIIVMPLELEWLDVGHRTVAGVLSSTFWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGRVEDAHRYLLRCARLNGRPVGEDGLSREALSKVAAAERVVRRPSYVDLFRTPRLRHISLCCMVVWFGVNFSYYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRHAGRRLTLAGTLLGTSLSLGFRLLVSSEMKSWSTALAVLGKGFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSLAPLAALLDGVWLSLPKLAYGGIALLAACTALLLPETKQAQLPETIQDVERKSAPSSLQEEEMPMKQVQD
What is the function of this protein?
Mediates sodium-independent multispecific organic anion transport.
What are the official names of this protein?
Solute carrier family 22 member 7, Organic anion transporter 2.
What is the protein family that this protein belongs to?
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
What are the subcellular locations of this protein?
Basolateral cell membrane; Multi-pass membrane protein. Note=Apical side of the renal tubule.
Protein: RL18_DESHY
Sequence: MITQIDRKAIRMKKHKRVRKSVFGTAERPRLAVFRSLNHIYAQVINDELGVTLATASSLDAEFKAAELAGGNVEGAKKVGDLVAKRALEKGVSKVVFDRGGNIYHGRIAAVAEAAREAGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: GLYC_LATVB
Sequence: MGQVIGFFQSLPEIINEALNIALICVALLATIKGMVNIWKSGLIQLLFFLTLAGRSCSHSFTIGRFHEFQSVTVNFTQFMSYAPSSCSVNNTHHYFKGPQNTTWGLELTLTNESMINITNSMRVFTNIHHNVTNCVQNISEHEGVLKWLLETMHLSISKPGKHIAPVMCERQKGLLIEYNLTMTKDHHPNYWNQVLYGLAKLLGSSKRLWFGACNKADCQMQSDHQHIKCNYSNCKGYTSFKYLIIQNTTWENHCEYNHLNTIHLLMSPIGQSFITRRLQAFLTWTLSDALGNDLPGGYCLEQWAVVWFGIKCFDNTAMAKCNQNHDSEFCDMLRLFDYNRNAIQSLNDQSQARLNLLTNTINSLVSDNLLMKNKLRELMNVPYCNYTRFWFINDTKNGRHTLPQCWLVSDGSYLNETRFRTQWLSESNSLYTEMLTEEYEKRQGRTPLSLVDLCFWSTLFYISTLFAHLVGFPTHRHLIGEGCPKPHRLTGSGICSCGHYGIPGKPVRWTKMSR
What is the function of this protein?
Forms the virion spikes together with glycoprotein G1.  The glycoprotein spike trimers are connected to the underlying matrix.  Class I viral fusion protein that directs fusion of viral and host endosomal membranes, leading to delivery of the nucleocapsid into the cytoplasm.  Membrane fusion is mediated by irreversible conformational changes induced by acidification.
What are the official names of this protein?
Pre-glycoprotein polyprotein GP complex, Pre-GP-C.
What is the protein family that this protein belongs to?
Belongs to the arenaviridae GPC protein family.
What are the subcellular locations of this protein?
[Glycoprotein G1]: Virion membrane; Peripheral membrane protein. Host endoplasmic reticulum membrane; Peripheral membrane protein. Host Golgi apparatus membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. SUBCELLULAR LOCATION: [Glycoprotein G2]: Virion membrane; Single-pass membrane protein. Host endoplasmic reticulum membrane; Single-pass membrane protein. Host Golgi apparatus membrane; Single-pass membrane protein. Host cell membrane; Single-pass membrane protein. Note=Binding to the stable signal peptide masks endogenous ER localization signals in the cytoplasmic domain of G2 to ensure that only the fully assembled, tripartite GP complex is transported for virion assembly. SUBCELLULAR LOCATION: [Stable signal peptide]: Virion membrane; Multi-pass membrane protein. Host endoplasmic reticulum membrane; Multi-pass membrane protein. Host Golgi apparatus membrane; Multi-pass membrane protein. Host cell membrane; Multi-pass membrane protein.
Protein: TRUA_SHESM
Sequence: MRIALGIEYDGSGYFGWQRQAEVDSVQGQLEQALSKVANEPISLFCAGRTDAGVHATGQVVHFETNAIRNEGAWTLGVNANLPDNIAVRWAKEVDDSFHARFSATARRYRYVIYNHNFRPGILRHGVSHYHGDIDADKMHVAAQALLGEQDFTSFRAVQCQSKTPFRNVHSVKVTRQGMYVIVDISANAFLHHMVRNIVGSLLEIGLGNQPLTWMADLLALKDRNQAAATAKPNGLYLVDVTYPEQYQLPKLALGPLFMLD
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: LUXS_STRPC
Sequence: MTKEVIVESFELDHTIVKAPYVRLISEEFGPKGDRITNFDVRLVQPNQNSIETAGLHTIEHLLAKLIRQRIDGMIDCSPFGCRTGFHLIMWGKHSSTDIAKVIKSSLEEIATGITWEDVPGTTLESCGNYKDHSLFAAKEWAQLIIDQGISDDPFSRHVI
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: HRP2_PLAFA
Sequence: MVSFSKNKVLSAAVFASVLLLDNNNSEFNNNLFSKNAKGLNSNKRLLHESQAHAGDAHHAHHVADAHHAHHVADAHHAHHAANAHHAANAHHAANAHHAANAHHAANAHHAANAHHAANAHHAANAHHAANAHHAANAHHAANAHHAANAHHAANAHHAADANHGFHFNLHDNNSHTLHHAKANACFDDSHHDDAHHDGAHHDDAHHDGAHHDDAHHDGAHHDGAHHDGAHHNATTHHLHH
What are the official names of this protein?
Histidine-rich protein PFHRP-III.
Protein: RSMH_MYCSS
Sequence: MKLCATSSEPARAAWPLSEPALAYFPDARSASDRDLAAGAYSPGVAMEHIPVLLDRCVELLTPALTRRNPDGRGAVLVDATLGAGGHAHRFLSDLPGLHLIGLDRDPQALQIAGERLAPFGDRVSLVRTRYDGIDDALAQTGVAEVSGFLFDLGVSSMQLDRTERGFSYSADAPLDMRMDSDAPLTAADVVNTFAEKDITRILREFGEERFAARIAKHIVRRRPLNTTGELVELLYDAIPAPARRTGGHPAKRTFQALRIAVNSELDSLRAAVPAALAALETGGRIVVMAYQSLEDRIVKTEFAAATASRTPPGLPVELPGHEPEFVALTRGAERATPEEIERNPRSAPVRLRALEKVAGRPTTARRDAR
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_DESVM
Sequence: MFITFEGMEGSGKSTALNRVQQVLLDAGHGVLLTREPGGSRLGRTLRSILLDLSNDDIVPEAELFLYLADRAQHVGQVIRPALDEGVVVLSDRYADSTVVYQGYGRGLDPERLRELNDMAVGGLWPDLTLVFDLPPEEGLRRAMTRNLREGTSVSEGRFEAEHLAFHARVREGYLTWAALHPARFRVVDATRTPDEVFEDVMRAVRSVLSAPARP
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.