PharMolix/UniProtQA huggingface dataset:
Protein: DNAJ_PSEPW
Sequence: MSKRDYYEVLGVERGASEADLKKAYRRLAMKYHPDRNPGDKESEDKFKEANEAYEVLSDASKRAAFDQYGHAGVDPSMGGGGAGFGGANFSDIFGDVFSDFFGGGRGGGRGGAARGSDLRYTLELNLEEAVRGTTVSIRVPTLVNCQPCDGSGAKKGSTPSTCPTCGGIGQVRMQQGFFSVQQTCPRCHGQGKIITDPCGSCHGEGRVEEYKTLSVKVPAGVDTGDRIRLSGEGEAGTHGGPTGDLYVVINVREHEIFQRDGKHLYCEVPISYTDAALGGELEVPTLDGRVKLKIPEGTQTGKQFRLRGKGVAPVRGGGAGDLLCRVAVETPVNLSRRQRELLEELRDSLEGDSSHSPKANGWFDGVKRFFGDL
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPK_STRPC
Sequence: MSQEKYIMAIDQGTTSSRAIIFNQKGEKVSSSQKEFPQIFPHAGWVEHNANQIWNSVQSVIAGAFIESSIKPSQIEAIGITNQRETTVVWDKKTGVPIYNAIVWQSRQTAPIAEQLKQDGHTKMIHEKTGLVIDAYFSATKIRWILDHVPGAQERAEKGELLFGTIDTWLVWKLTDGAVHVTDYSNAARTMLYNIKDLTWDDEILELLNIPKDMLPEVKSNSEIYGKTAAFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNTGDEMQLSSNNLLTTIGYGINGKVHYALEGSIFIAGSAIQWLRDGLKMIETSPESEQFALASTSDDEVYVVPAFTGLGAPYWDSNARGSVFGLTRGTSKEDFVKATLQSIAYQVRDVIDTMQVDSGIDIQQLRVDGGAAMNNMLMQFQADILGIDIARAKNLETTALGAAFLAGLAVGYWEDMDALKELNATGQLFKASMNESRKEKLYKGWKRAVKATQVFTQEEDADDDAK
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: PTH_MYCBP
Sequence: MAEPLLVVGLGNPGANYARTRHNLGFVVADLLAARLGAKFKAHKRSGAEVATGRSAGRSLVLAKPRCYMNESGRQIGPLAKFYSVAPANIIVIHDDLDLEFGRIRLKIGGGEGGHNGLRSVVAALGTKDFQRVRIGIGRPPGRKDPAAFVLENFTPAERAEVPTICEQAADATELLIEQGMEPAQNRVHAW
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD2_PSEMY
Sequence: MSAVLSPKLIDGKAAAARVLAEVTEDVRTLKAAGIKPALAVVLVGDDPASQVYVRNKVLRAEECGIRSLEHKLPADTAEADLLALIHSLNADYSVHGILVQLPLPAHIDETRVLQAINPLKDVDGFHAENVGGLSQGRDVLTPCTPAGCLRLLQDSCGDLTGKHAVVIGRSNIVGKPMAALLLKAHCSVSVVHSKSANLRELCRQADIVVAAVGKPRLVDADWLKPGAVVIDVGINRIDEGGRSRLVGDVDFDSALTRAAAITPVPGGVGPMTIAFLMKNTLVAARLQHPATGLPLSTLENPA
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD 2.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: GPDA_MANSM
Sequence: MSIQASPVTILGAGSYGTALAIALSRNGYPTYLWGHNPTACAQMAQERQNARFLPDISFPEALRVESDLKSAVEKSKDLLIVVPSHVFGEVIQQIKPFLHNRHRIIWATKGLERGTGRLLQNLVEQELGSQYPLAVLSGPTFAKELAAGLPTAITLAAENEQFAKEFQARIHCSKHFRVYINNDMVGVQLGGAIKNVIAISAGMSDGMGFGANARTALITRGIAEISRLGVSLGANVNTFMGMSGLGDLVLTCTDNQSRNRRFGMMLGQGVDARTAMDEIGQVVEGYYNTKEAYMLAQKQGIEMPITEQIYQVLFCGKDAKEAATALLGRKSKVE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y124_LISIN
Sequence: MSELIKVFKYDADGIFERDDLIVLEKGEKVPDGYTLIAPPVPSVNPVFNVKTQKWSAGEDASVMDPPPLSEIEKLTQDYADLMLYVAEVEQKTEQTQQDNANLLLSLAEAGVL
What are the official names of this protein?
Uncharacterized protein Lin0124/Lin2378/Lin2564.
Protein: LEPA_STRS2
Sequence: MNLEDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPIINKIDLPAADPERVRQEIEDVIGLDASEAVPTSAKAGIGIEEILEQIVEKVPAPTGDVEAPLQALIFDSVYDPYRGVILQVRIVNGVVKPGDTIQMMSNGKTFDVTEVGIFTPKAIGRDYLATGDVGYIAASIKTVADTRVGDTVTLAENPASEPLAGYKQMNPMVFAGIYPIDSNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERIEREFNIDLIMTAPSVVYHVNMTDGEMIDVANPSEFPDPTKIATIEEPYVKAQIMVPQEYVGAVMELAQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYEISEYRSSKLVKMDILLNGDKVDALSFIVHKEFAYERGKIIVDKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDEDDKK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TIM10_PICSO
Sequence: MFGLGGAPQISSEQKLQAAEAELDMVTGMFNQLVDQCHSKCINKSYGDSDITKQEALCLDRCVAKYFDTNVQVGEHMQKLGQSGQFMGRK
What is the function of this protein?
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane.  Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane.  Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit Tim10.
What is the protein family that this protein belongs to?
Belongs to the small Tim family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: URE2_LEPCP
Sequence: MTPGELLTDGADLVINSGRRTLTLVVENASDRPIQVGSHYHFAETNAGLSFDRAAARGMRLNIASGTAVRFEPGQQRTIELVDLAGDRQVWGFRGLVQGRL
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECOT_ECO27
Sequence: MKTILPAVLFAAFATTSAWAAESVQPLEKIAPYPQAEKGMKRQVIQLTPQEDESTLKVELLIGQTLEVDCNLHRLGGKLESKTLEGWGYDYYVFDKVSSPVSTMMACPDGKKEKKFVTAYLGDAGMLRYNSKLPIVVYTPDNVDVKYRVWKAEEKIDNAVVR
What is the function of this protein?
General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases.
What are the official names of this protein?
Ecotin.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I11 (ecotin) family.
What are the subcellular locations of this protein?
Periplasm.
Protein: GERKB_BACSU
Sequence: MEKARISIRQLFVMIIIFELGSSLLITPGSMAGRDAWIAVLLGCAIGLFLFYLYQGIYQCYPNSSPKEYMDDMLGTKLSWLFSFLYILYFAYIAARVLRDFGEMLLTFAYHDTPIIIVNALLMVVSIYAVRKGIEVLARAAELLFGAMYLLGAIGLVLIIVSGTIDPHNLKPVLANGISPVLHSVFTQTMYVPFGEVVLFVMIFPNLNDRKDVKKMGMIAMAISGLIVALTVAINISVLDVDLTLRSQFPLLSTIQTIKVEEFLDRLDVFFMLALIIGGFFKVSLYLYATVVGTSTLFKEKNPSQLAYPMGLGILILSITIATNFSEHLNEGLNVVPLYIHLPFQLLFPLFLFIVAVWKKKRREKSKGEEAKK
What is the function of this protein?
Involved in the germination response to the combination of glucose, fructose, L-asparagine, and KCl.
What are the official names of this protein?
Spore germination protein KB.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATG5_COCIM
Sequence: MAASSASTSAIQQRVWQGRIPLQIVLSPSECRIYDQSDPYIISIPRLSYLPFILPRLFSFFSSSLIDPDVQAHDGWFSFEGVPLKWHYPVGLLYDLYAGAEPITSKSLSSPGSEREHYVRGGTRENISESGAEGEKDDNHGHDHEFKRDALPWRLMVHFHDWPEQDLIRLDPEGKILHDAFINSVKEADCLRNGTAKRIMALSKEDSSGLWKSVEEHNLPAYHRIHNTLLLPTPPTPFRNIPIRIFLPAPPDSPSPSLKVIQSPIPPLIQPTASPSSSISSASRQMQPQVQTIGTALNSLLPSLFPSKRTPMLAKPVLHGAVVPMSAPVEEVVKCAGYADGWLGVVVSMVG
What is the function of this protein?
Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.  Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation.  Required for selective autophagic degradation of the nucleus (nucleophagy).  Also required for mitophagy, which eliminates defective or superfluous mitochondria in order to fulfill cellular energy requirements and prevent excess ROS production.  Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function.  The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 and ATG8 association to the vesicle membranes (By similarity).
What are the official names of this protein?
Autophagy protein 5.
What is the protein family that this protein belongs to?
Belongs to the ATG5 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: C91_GEMKI
Sequence: MMAKLMITVMMVLLLSLQQGADGRSKRWRKNQMAASSIMRNLITARGVPPRFCRDKNCNEDSECNQWCTGGCSSVKGNCES
What are the official names of this protein?
Turripeptide Gkn9.1.
What is the protein family that this protein belongs to?
Belongs to the Pg turripeptide superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ECOT2_LEIBR
Sequence: MSAAAGKTLADYKAPYPKPTSRQRRYVILLDPKGDNAELNDYKVELIPGRVKLLDGANHYFLGGKIEEKTIDGWGYPYYVVTLAEMAGTAMLPLGNAAHKKLRFVPLHTSSLYRYNSKLPIVVYVPKDGVLRYRIWTAKLSGRGKAKSIKAKEM
What are the official names of this protein?
Ecotin-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I11 (ecotin) family.
Protein: NPD_SYMTH
Sequence: MLEQIQDFARALQASRYAVALTGAGASTESGLPDFRSNTGLWKDVDPVSLISMTALRRRPVDFYRFYRMRFSHLWGAQPNPVHKVLAALQREGLLKRLITQNVDGLHQAAGSPDVIELHGSLRECQCLRCGRRFPSRLIDVEVETEADIPRCPECGGVLKPGVVLFEEALPADAIEAAIEAAMKADLFLVVGSSLEVGPANQLPVLAVQHGGRLAIFNLTPTFLDPRATWIFREKAGQALGALAAELGISL
What is the function of this protein?
NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.
What are the official names of this protein?
NAD-dependent protein deacetylase, Regulatory protein SIR2 homolog.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class U subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTOR_HUMAN
Sequence: MARILLLFLPGLVAVCAVHGIFMDRLASKKLCADDECVYTISLASAQEDYNAPDCRFINVKKGQQIYVYSKLVKENGAGEFWAGSVYGDGQDEMGVVGYFPRNLVKEQRVYQEATKEVPTTDIDFFCE
What are the official names of this protein?
Otoraplin, Fibrocyte-derived protein, Melanoma inhibitory activity-like protein.
What is the protein family that this protein belongs to?
Belongs to the MIA/OTOR family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYP_ANASK
Sequence: MHAVRYSQAFIPTLKEAPADAQVASHKLLVRAGFIRQLGAGIYDYLPLAKRSLAKVEAIVREEMDAIGGQEFYLPALHPAEIWKESGRWDVMGDNMFRLKDRKGGDYCLGMTHEEIFTAVARDELRSYRQLPQVWYQIQTKFRDEPRPKSGLLRVRQFTMKDAYSFDVDRAGLDRSYEDQRRAYEKIFTRCGLDFVAVQAHSGSMGGSESSEFMVRTEAGEDLVAACPRCRYAANTETATSRVAAEADGPGLGAPEKFATPGVVTIEALEQAPHSVPARRQLKTLVYMADEKPVIAVVRGDQELNEAKLQTATGAVAVRPAHPEEIPPLMGARAGSLGAVRFTRARVLVDPSLADRKDMVTGANEDGFHLRGVDVRRDVLAHGATLAELRTVKAGEGCPRCDGTLDVFKALEIGHIFKLGTKYSESMKATVLDAEGKQVPIVMGSYGIGVERILAAAIELHHDDNGIVFPMAIAPFHATVLTLGPEPELRKAAEEVVAALGKEGVEVLFDDRDERAGVKFKDADLLGIPIRIAVGKKGLAAGNVEWKLRKGGAVELVPVGEVARKAAEAVRAAT
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRB_PARMW
Sequence: MPAYDLTAPYTPKGDQPTAIKQLVQGVNGGERYQTLLGATGTGKTFTMANVIAQTGRPALVLAHNKTLAAQLCNELREFFPENAVEYFISYYDYYQPEAYVPVSDTYIAKTASINEEIDMLRHSATRSLFERRDVIVVASISCIYGLGIPSEYLKAAVKFEVGETLNIRSQLRELVNNQYSRNDTEIARGRFRMKGDVLEIGPAYEDRLVRIELFGDEVEAIRYVDPTTGEILQSLETVNIYPAKHFVTPKDRLDSAIGEIRQELRDRLDFLNGEGKLLEAQRLEQRTKYDLEMLGQVGYCNGVENYARHLAGREEGTPPECLIDYFPKDWLLIVDESHVTCSQLQAMYNGDQARKKVLIEHGFRLPSAADNRPLKGEEFWEKAHQTVFVSATPGNWELEVSGGEVAQQVIRPTGVLDPIVEVRPTTGQVDDLLGEIRDRASKQQRVLVTTLTKRMAEDLTDYLAENEVRVRYLHSEIHSIERIEIIQDLRLGEYDVLVGVNLLREGLDLPEVSLVAILDADKEGFLRAERSLIQTIGRAARHVEGVALLYADNMTESMAKAISETERRRKIQQTYNEKHGIVPTAAGKKASNSILSFLELSRKLKQDGPDADLVQVAGKAAQALEEDPDAGLALEALPELIDQLEGKMKEAAKKLDFEDAANLRDRIKQLRQKMAG
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSA_MYCTU
Sequence: MSFPYFISPEQAMRERSELARKGIARAKSVVALAYAGGVLFVAENPSRSLQKISELYDRVGFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLANVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKRPELYRITYDGSIADEPHFVVMGGTTEPIANALKESYAENASLTDALRIAVAALRAGSADTSGGDQPTLGVASLEVAVLDANRPRRAFRRITGSALQALLVDQESPQSDGESSG
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.  The M. tuberculosis proteasome is able to cleave oligopeptides not only after hydrophobic but also after basic, acidic and small neutral residues (PubMed:16468985).  In complex with the ATPase Mpa, degrades protein targets conjugated to a prokaryotic ubiquitin-like protein (Pup).  Among the identified substrates of the M. tuberculosis proteasome are the pupylated FabD, PanB and Mpa proteins (PubMed:17082771).  One function of the proteasome is to contribute to M. tuberculosis ability to resist killing by host macrophages, since the core proteasome is essential for persistence of the pathogen during the chronic phase of infection in mice (PubMed:18059281).  Likely functions to recycle amino acids under nutrient starvation, thereby enabling the cell to maintain basal metabolic activities (PubMed:20711362) (By similarity).  The mechanism of protection against bactericidal chemistries of the host's immune response probably involves the degradation of proteins that are irreversibly oxidized, nitrated, or nitrosated.  A proteolysis-independent activity of the proteasome core is required for optimal growth of M. tuberculosis in mouse lungs and for RNI resistance; in contrast, long-term survival of M. tuberculosis in stationary phase and during starvation in vitro and in the chronic phase of mouse infection required a proteolytically active proteasome (PubMed:20711362).
What are the official names of this protein?
Proteasome subunit alpha, 20S proteasome alpha subunit, Proteasome core protein PrcA.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DJC43_ORYSJ
Sequence: MAAAEENSSLFLIFILTMIALPLVPYTIMRLCRAANVKAKTIHCRCSGCHRSGKYRKSIYKRISNFSTCSNLTILLLWIVMIFLVYYIKHVSREVQVFEPYSILGLEPGASESDIKKSYRRLSIQYHPDKNPDPEAHKYFVEFISKAYQALTDPVSRENYEKYGHPDGRQGMQMGIALPKFLLNMDGASGGIMLLGIVGLCILLPLMIAVIYLSRSSKYTGNYVMHQTLSTYYYFMKPSLAPSKVMDVFIKAAEYMEMPVRRSDDEPLQKLFVAVRSELNLDLKNIRTEQAKFWKQHPSLVKMELLIQAHLTGESFALTPALLKDYRHMLELAPRLLDELVKIALLPRSPHGFGWLRPAIGVIELSQNIIQAVPLSARKASGGNSEGIAPFLQLPHFTETVVKKIARKKIRSFQEFCDMPVEERATLLTQVAGLSDEGAQDVELVLEMIPSIEVDIKCETEGEEGIQEGDVVTMYAWVSLHRRNGLTAALPHAPSFPFHKEENFWLLLADAASNEVWLSQKVSFMDETTAITAASKAIQETQEALGASAKEIGIAIREAVDRVKKGSRLVMGKFQAPAEGTHNLTSFCLCDAWIGCDTKTSLKLKVLKRSRAGTRGHVAEEGPVAEDGIEEEEEEEEEEYDDYESEYSDDEEDEKSKGKGKVANGVAHQKANSDIDSGSDD
What is the function of this protein?
May be required for integral membrane and secreted preprotein translocation across the endoplasmic reticulum membrane.
What are the official names of this protein?
DnaJ protein ERDJ2, Chaperone protein dnaJ C43, OsDjC43, Endoplasmic reticulum dnaJ domain-containing protein 2, OsERdj2.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: API6_SOLTU
Sequence: NSSYRIISIGRGALGGDVYLGKSPNSDAPCPDGVFRYNSDVGPSGTPVRFIPLSGGIFEDQLLNIQFNIPTVKLCVSYTIWKVGNLNAYFRTMLLETGGTIGQADNSYFKIVKSSKIGYNLLSCPFTSIICLRCPEDQFCAKVGVVIQNGKRRLALVNENPLDVLFQEV
What is the function of this protein?
Inhibitor of cathepsin D (aspartic protease).  May also inhibit trypsin and chymotrypsin (serine proteases).  Protects the plant by inhibiting proteases of invading organisms.
What are the official names of this protein?
Aspartic protease inhibitor 6, API-6.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I3 (leguminous Kunitz-type inhibitor) family.
What are the subcellular locations of this protein?
Vacuole.
Protein: NHAA_ECOHS
Sequence: MKHLHRFFSSDASGGIILIIAAILAMIMANSGATSGWYHDFLETPVQLRVGSLEINKNMLLWINDALMAVFFLLVGLEVKRELMQGSLASLRQAAFPVIAAIGGMIVPALLYLAFNYADPITREGWAIPAATDIAFALGVLALLGSRVPLALKIFLMALAIIDDLGAIIIIALFYTNDLSMASLGVAAVAIAVLAVLNLCGVRRTGVYILVGVVLWTAVLKSGVHATLAGVIVGFFIPLKEKHGRSPAKRLEHVLHPWVAYLILPLFAFANAGVSLQGVTLDGLTSILPLGIIAGLLIGKPLGISLFCWLALRLKLAHLPEGTTYQQIMAVGILCGIGFTMSIFIASLAFGSVDPELINWAKLGILVGSISSAVIGYSWLRVRLRPSV
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SSPO_HALH5
Sequence: MVRKKANHSRPGMNAAKAQGKDAGLTSQFHAEIGQEPLNQAQRQNNKKRKKNQ
What are the official names of this protein?
Small, acid-soluble spore protein O, SASP O.
What is the protein family that this protein belongs to?
Belongs to the SspO family.
Protein: RDGC_PSEA7
Sequence: MWFRNLLVYRLTQDLQLDADALEKALGEKPARPCASQELTTYGFTAPFGKGPDAPLVHVSQDFFLVSARKEERILPGSVVRDALKEKVDEIEAQQMRKVYKKERDQLKDEIVQTLLPRAFIRRSSTFAAIAPSLGLILVDSASAKKAEDLLSTLREALGSLPVRPLSVKVAPTATLTDWVKTQEAAGDFHVLDECELRDTHEDGGVVRCKRQDLTSEEIQLHLTAGKLVTQLSLAWSDKLSFVLDDKLAVKRLRFEDLLQEQAEKDGGEDALGQLDASFTLMMLTFAEFLPALFEALGGEEIPQGV
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: GLMU_BRUAB
Sequence: MTDRTCLSIVLAAGEGTRMKSNLPKVLHRVAGLPLVCHVVNAVRGTGKSDVALVVGRGAEDVRSAVEKIAGPVSAFEQKERLGTAHAVLAAHEAIARGYDDLLIVFGDTPLIEAQSLLAARERLAQGADLVVIGFRPASPHGYGRLIEEGGQLVAIIEEKEATDEQKKIGFCNGGLMALRGQHALALLDAVGNDNAKGEYYLTDIVAIAHGKGLNVTAIEVPVDNVIGINNRAELAEAETIWQNRKRRELMLSGVTLIAPETVFFSYDTVIEPDVVIEPNVFFGPSVHVASGALIHSFSHLEGAQVGEKAEIGPFARLRPGADLAEKSKVGNFCEVKNAKVGKGAKINHLAYIGDAVIGASSNIGAGTITCNYDGYNKFKTIIGDNAFIGSNSSLVAPVEIGDNAYIASGSVITADVPADALALGRARQETKEGRAKILREKYAAIKAAKSVSK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RANB3_MACFA
Sequence: MADLANEEKPAIAPPVFVFQKDKGQKRSAGGSSPEGGEDSDREYGNYCPPVKRERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQPKALSQTVPSSGTNGVSLLADCTGAVPAASPDTVARRSPSEAADEVCALEEKEPQKNESSNASEEEACEKKGPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAVESGSESSSQEATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQIDKASEKSIRITAMDTEDQGVKVFLISASSKDTGQLYAALHHRILALRSRVEQEQEAKMPVPEPGAAPSNEEDDSDDDDVLAPSGATAAGAGDEGDGQTTGST
What is the function of this protein?
Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein.  Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction.  In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex.  Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1.  Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner.  Negative regulator of TGF-beta signaling through interaction with the R-SMAD proteins, SMAD2 and SMAD3, and mediating their nuclear export (By similarity).
What are the official names of this protein?
Ran-binding protein 3, RanBP3.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.