PharMolix/UniProtQA huggingface dataset:
Protein: RIBC1_BOVIN
Sequence: MYQVDLPPDPKEVAAIEARRNQEREQQSRFFNVRTRVMGVDVEALNNQVEERKLQEATERSKEAAYGTNQVRYDLVAQMLEKEQAERTRRLAKKVQNFREQRQKLRNRCELDFWNSNQLWREFPAYLGDNAPYYGQASLQCFSGEDLERATYLRMQQEQFQYSLERQLQEQQQARVDENCADMLNDQLRLAMDMRAAQLAKLEESCRIAMMAATASANKAQAVKLAEQQGQEHQRQQEANLVEVQNQITSDLLTENPQVAQNPVAPHRVLPYCWKGMTPEQRATIRKVQETQHHEKEAQRQAEQALDAKWESQAINLAQAAKELEEQERELCAEFRRGLGSFNQQLAMEQNAQQNYLNSIIYTNQPTAQYHLQFNTSSR
What are the official names of this protein?
RIB43A-like with coiled-coils protein 1.
What is the protein family that this protein belongs to?
Belongs to the RIB43A family.
Protein: ATPA_POLSJ
Sequence: MQLNPAEISELIKSRIEGLTVSADIRNQGTVVSVTDGIVRIHGLSDVMQGEMLEFPATADGTPTYGLALNLERDSVGSVILGEYEHIAEGDTVKCTGRILEVPVGPELLGRVVNALGQPIDGKGPINAKMTDVIEKVAPGVIARKSVDQPLQTGLKSIDSMVPVGRGQRELIIGDRQTGKTAVAIDAIINQKGKGVSCVYVAIGQKASSIKNVVRSLEQAGAMEYTIVVAASASESAAMQYVSAYSGCTMGEYFRDRGEDALIVYDDLSKQAVAYRQVSLLLRRPPGREAYPGDVFYLHSRLLERAARVNEKYVEDFTKGAVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETSLFNAGIRPAINAGISVSRVGGAAQTKLIKNLSGGIRTDLAQYRELAAFAQFASDLDEATRKQLDRGARVTELLKQAQYSPLSISNMAATLFAVNKGFMDDVEVKKVLAFEHGLHAWLKDKNAALMAKLEANKAMDKDAEAELNTAVAAFKKAFA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PX11B_ARATH
Sequence: MSLDTVDKLVVFLAKRDGIDKLVKTFQYVAKLACWHVEATRPEAADRFKKWEVASGLSRKAFRTGRSLTGFNALRRNPGATPMIRFLAVLANSGEMVYFFFDHFLWLSRIGSIDAKLAKKMSFISAFGESFGYTFFIIIDCIFIKQRLKSLKKLQHSTDEPKEEIGAKISEIRGDIVMRLMGISANVADLLIALAEIHPNPFCNHTITLGISGLVSAWAGWYRNWPS
What is the function of this protein?
Involved in peroxisomal proliferation.  Promotes peroxisomal duplication, aggregation or elongation without fission.
What are the official names of this protein?
Peroxisomal membrane protein 11B, Peroxin-11B, AtPEX11b.
What is the protein family that this protein belongs to?
Belongs to the peroxin-11 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Multi-pass membrane protein.
Protein: PDXJ_AGRVS
Sequence: MPAKLSVNLNAIAMLRNRRDLPWPDVRHFGRLALQAGAQGLTVHPRPDQRHVRFSDLPLLRALIDDEFPKAEFNIEGYPSEDFLQLCEEAQPEQVTLVPDDPSQATSDHGWDFAAHQVFLTDVVARLKAAGMRVSLFADGDGNAQAVATAKATGADRIELYTGPYGSCYDAPEKAARELALLGATADAAHALGMGVNGGHDLTIANLPALAERIPFLAEVSIGHALTADALEFGMAETVRRFRRACGELA
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSA_STAES
Sequence: MEEHYYVSIDIGSSSVKTIVGEKFHNGINVIGTGQTYTSGIKNGLIDDFDIARQAIKDTIKKASIASGVDIKDVFLKLPIIGTEVYDESNEIEFYEDTEIDGTHIESVLEGIRDKNDVPETEVINVFPIRFVVDKDNEVSDPKELIARHSLKVDAGVIAIQKSILINMIKCVEACGVDVLDVYSDAYNYGFILTPTEKELGACVIDIGEDLTQVAFYERGELVDAESIEMAGRDITDDIAQGLNTTYDTAEKVKHQYGHAFYDSASDQDVFSVDQVDSDEHVQYTQKDLSDFIEQRVEDIFFEVFDVLQELGLTKVNGGFVVTGGSANLLGVKELLQDMVSEKVRIHTPSQMGIRKPEFSSAISTISSSIAFDELLDYVTISYQDNEEFEEEVIETDKDTETKSSGFDWFKRKSNKKENDEVAPEAPREESYEDRENHLEDEQQTEGKAKEESKFKKLMKSLFE
What is the function of this protein?
Cell division protein that is involved in the assembly of the Z ring.  May serve as a membrane anchor for the Z ring.
What are the official names of this protein?
Cell division protein FtsA.
What is the protein family that this protein belongs to?
Belongs to the FtsA/MreB family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes to the Z ring in an FtsZ-dependent manner. Targeted to the membrane through a conserved C-terminal amphipathic helix.
Protein: COXX_RENSM
Sequence: MRLTQAPATTAAAGNPPHKLGFAAKTKAYIALTKPRVMELLLVTTLPTMIFAARGLPNIWLILATMIGGAFAAGSAGAFNCYIDRDIDKIMHRTEDRPLVTGAVTPREALVFSWALGILSIAILWFGANPLAGLLGIAAIFFYVVVYTLILKRRTAQNIVWGGVAGCMPVLIAWAAVTNKVEWPAIILFMVIFLWTPPHYWPLSMRYSEDYKAANVPMLGAVAGARIVSVQVVLYTWAMVVCSLLLIPLGHACIVYTVVAGAAGLWFLLEAHRLHSKASHDTVTNKSAMKVFHGSISYLTLLFVALAVDPFVGMPLMG
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SEPT9_MOUSE
Sequence: MKKSYSGVTRTSSGRLRRLADPTGPALKRSFEVEEIEPPNSTPPRRVQTPLLRATVASSSQKFQDLGVKNSEPAARLVDSLSQRSPKPSLRRVELAGAKAPEPMSRRTEISIDISSKQVESTASAAGPSRFGLKRAEVLGHKTPEPVPRRTEITIVKPQESVLRRVETPASKIPEGSAVPATDAAPKRVEIQVPKPAEAPNCPLPSQTLENSEAPMSQLQSRLEPRPSVAEVPYRNQEDSEVTPSCVGDMADNPRDAMLKQAPASRNEKAPMEFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSEERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERVYFKQRITADLLSNGIDVYPQKEFDEDAEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSNIHFEAYRVKRLNEGNSAMANGIEKEPEAQEM
What is the function of this protein?
Filament-forming cytoskeletal GTPase (By similarity).  May play a role in cytokinesis (Potential).
What are the official names of this protein?
Septin-9, SL3-3 integration site 1 protein.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=In an epithelial cell line, concentrates at cell-cell contact areas. After TGF-beta1 treatment and induction of epithelial to mesenchymal transition, colocalizes with actin stress fibers.
Protein: KDPA_PARD8
Sequence: MNTEILGVALQILLLLVISYPLGKHIAKVYKEGNDCMRFMAPIERFIYKLAGINPNEEMDWKAFLKSLLIINVFWFFWGMILLVSQGYLPLNPDGNSGQSPDLAFNTCISFMVNCNLQHYSGESGLTYFTQLFVIMLFQFITAATGMAAMAGIMKSMAAKTTKTIGNFWHYLVISCTRILFPMSLIVGFILIIQGTPMGFDSKMTIPTLEGAEQTVSQGPTAAIVPIKQLGTNGGGYFGVNSSHPLENPTYLTNIVECWSILIIPMALVFALGFYLKRKKLGYVIYGVMLFAYLLGVFCNVHYEMAGNPKIDEMGIDQSCGAMEGKETRLGPGATALWSVTTTVTSNGSVNGMHDSTMPLSGMVEMLNMQINTWFGGVGVGFMNYYAFLIIAVFISGLMVGRTPEFLGKKVEAREMKIATIVSLAHPFVILIFTAISSYVWVYAPEFVESEGGWLNNPGFHGFSEMLYEYTSSSANNGSGFEGLGDNTYFWNYTCGLALIISRYLPIVGQVAIAGLLANKKYTPESAGTLKTDTVTFGVMTFFVIVIVAALSFFPAQTLGPIAEYFSIY
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HLDE_YERPE
Sequence: MKVTLPDFRRAGVLVVGDVMLDRYWYGPTCRISPEAPVPVVKVDTIEERPGGAANVAMNIASLGAVARLVGLTGIDDAARALICKLSEVRVRCDFVSVPTHPTITKLRVLSRNQQLIRLDFEEGFDGVDPTPIFERIQLALPQIGALVLSDYAKGALNSVQPMIQLARKANVPVLIDPKGSDFERYRGATLLTPNLSEFEAVVGRCKNEEELVNRGMQLVADFELSALLVTRSEQGMTLLQLGKPPLHLPTQAKEVFDVTGAGDTVIGVLAAALAAGNSLEESCFLANAAAGVVVGKLGTSTVSPIELENAIRGRAETGFGVMDEQQLKIAVAQARQRGEKVVMTNGIFDILHAGHVSYLANARKLGDRLIVAVNSDASTKRLKGEKRPVNPLEQRMVVLGALEAVDWVVPFEEDTPQRLIADILPDLLVKGGDYKPHEIAGSEEVWAAGGEVKVLNFEDGVSTTNIIQSIKNGRG
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: S15A1_RABIT
Sequence: MGMSKSLSCFGYPLSIFFIVVNEFCERFSYYGMRALLILYFRNFIGWDDNLSTVIYHTFVALCYLTPILGALIADAWLGKFKTIVWLSIVYTIGQAVTSLSSVNELTDNNHDGTPDSLPVHVAVCMIGLLLIALGTGGIKPCVSAFGGDQFEEGQEKQRNRFFSIFYLAINAGSLLSTIITPMVRVQQCGIHVKQACYPLAFGIPAILMAVSLIVFIIGSGMYKKFKPQGNILSKVVKCICFAIKNRFRHRSKQFPKRAHWLDWAKEKYDERLIAQIKMVTRVLFLYIPLPMFWALFDQQGSRWTLQATTMSGRIGILEIQPDQMQTVNTILIIILVPIMDAVVYPLIAKCGLNFTSLKKMTIGMFLASMAFVAAAILQVEIDKTLPVFPKANEVQIKVLNVGSENMIISLPGQTVTLNQMSQTNEFMTFNEDTLTSINITSGSQVTMITPSLEAGQRHTLLVWAPNNYRVVNDGLTQKSDKGENGIRFVNTYSQPINVTMSGKVYEHIASYNASEYQFFTSGVKGFTVSSAGISEQCRRDFESPYLEFGSAYTYLITSQATGCPQVTEFEDIPPNTMNMAWQIPQYFLITSGEVVFSITGLEFSYSQAPSNMKSVLQAGWLLTVAVGNIIVLIVAGAGQINKQWAEYILFAALLLVVCVIFAIMARFYTYVNPAEIEAQFEEDEKKKNPEKNDLYPSLAPVSQTQM
What is the function of this protein?
Electrogenic proton-coupled amino-acid transporter that transports oligopeptides of 2 to 4 amino acids with a preference for dipeptides.  Transports neutral and monovalently charged peptides with a proton to peptide stoichiometry of 1:1 or 2:1 (PubMed:8139693, PubMed:9051570, PubMed:12082113).  Primarily responsible for the absorption of dietary di- and tripeptides from the small intestinal lumen (PubMed:8139693).  Mediates transepithelial transport of muramyl and N-formylated bacterial dipeptides contributing to recognition of pathogenic bacteria by the mucosal immune system.
What are the official names of this protein?
Solute carrier family 15 member 1, Intestinal H(+)/peptide cotransporter, Oligopeptide transporter, small intestine isoform, Peptide transporter 1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: BGAL5_ORYSJ
Sequence: MGRGCLAALLGGAVAVAVLVAVVHCAVTYDKKAVLVDGQRRILFSGSIHYPRSTPEMWDGLIEKAKDGGLDVIQTYVFWNGHEPTPGNYNFEGRYDLVRFIKTVQKAGMFVHLRIGPYICGEWNFGGFPVWLKYVPGISFRTDNEPFKNAMQGFTEKIVGMMKSENLFASQGGPIILSQIENEYGPEGKEFGAAGKAYINWAAKMAVGLDTGVPWVMCKEDDAPDPVINACNGFYCDTFSPNKPYKPTMWTEAWSGWFTEFGGTIRQRPVEDLAFGVARFVQKGGSFINYYMYHGGTNFGRTAGGPFITTSYDYDAPLDEYGLAREPKFGHLKELHRAVKLCEQPLVSADPTVTTLGSMQEAHVFRSSSGCAAFLANYNSNSYAKVIFNNENYSLPPWSISILPDCKNVVFNTATVGVQTNQMQMWADGASSMMWEKYDEEVDSLAAAPLLTSTGLLEQLNVTRDTSDYLWYITSVEVDPSEKFLQGGTPLSLTVQSAGHALHVFINGQLQGSAYGTREDRKISYSGNANLRAGTNKVALLSVACGLPNVGVHYETWNTGVVGPVVIHGLDEGSRDLTWQTWSYQVGLKGEQMNLNSLEGSGSVEWMQGSLVAQNQQPLAWYRAYFDTPSGDEPLALDMGSMGKGQIWINGQSIGRYWTAYAEGDCKGCHYTGSYRAPKCQAGCGQPTQRWYHVPRSWLQPTRNLLVVFEELGGDSSKIALAKRTVSGVCADVSEYHPNIKNWQIESYGEPEFHTAKVHLKCAPGQTISAIKFASFGTPLGTCGTFQQGECHSINSNSVLEKKCIGLQRCVVAISPSNFGGDPCPEVMKRVAVEAVCSTAA
What are the official names of this protein?
Beta-galactosidase 5, Lactase 5.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 35 family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: ACPS_CAMJR
Sequence: MRVGCDIIAISRIEKIHSRHGKNFLDKFLSPKEQILIKNPATLAGLWAAKEAASKALGVGICELCSFFDIEISKDEKNAPKLKYSQKITKDFNITQTSLSISHDNGFAIAIVAVV
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANB_LISMH
Sequence: MKKPVDFFAMKENGEKITMITAYDYPSAKNVEQAEADMILVGDSLGMVVLGYDSTVPVTMDDMIHHTKAVKRGAPDTFVVTDMPFMTYHGSVDETIQNARKIIQESGAHAVKLEGAGEVVNKIARLTEAGAPVVAHLGLTPQSVGLTGSYKVRAKSAQEAQELMDNALAVEAAGAIAIVLEAIPRQLAEKVSKALSIPTIGIGAGVETDGQVLVYHDIIGYGISRRAKFVKAYAEIDETIEPALASYVKEVKAATFPEVKHSFTMAEEDLKGLYGRE
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_NITMS
Sequence: MAKQAGKGVEEFRPYVTKVIPVGANIVCADNSGAKILEVINVPRHRTRASRLPSASVGDFCNVVVKKGPAELRKQVYGAVIIRQKYPVRRLNGVRVCFEDNAAVLITPEGETKGTDIKGPVAAEASEKWPRVANLASMVV
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: TRPB_SHEPW
Sequence: MSKLNPYFGEYGGMYVPQILMPALKQLETAFIEAQQDEAFQKEFTDLLKNYAGRPTALTLTRNLSPNPLAKIYLKREDLLHGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVATALACALLDLKCKVYMGAKDVERQSPNVFRMKLMGAEVIPVTSGSATLKDACNEAMRDWSASYDKAHYLLGTAAGPHPFPTIVREFQRMIGAETKQQILEREGRLPDAVIACVGGGSNAIGMFADFIDEEEVALIGVEPAGKGIDTPMHGAPLKHGKTGIFFGMKAPLMQDSEGQIEESYSVSAGLDFPSVGPQHAHLAATGRATYESATDDEALETFQLLARSEGIIPALESAHALAYAVKLAKAATKETLLVVNLSGRGDKDIFTVADILEKQQADSSTTEESGNE
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: Y433_HAEI8
Sequence: MAGHSKWANIKHRKAAQDAQRGKIFTKLIRELVTAAKIGGGDVSANPRLRAAVDKALSNNMTRDTINRAIDRGVGGGDDTNMETKIYEGYGPGGTAVMVECLSDNANRTISQVRPSFTKCGGNLGTEGSVGYLFSKKGLILIAEADEDALTEAAIEAGADDIQPQDDGSFEIYTAWEDLGSVRDGIEAAGFKVQEAEVTMIPSTTVDLDIETAPKLLRLIDMLEDCDDVQNVYHNGEICDEVASQL
What are the official names of this protein?
Probable transcriptional regulatory protein NTHI0433.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TA2R8_PONPY
Sequence: MFSPADNIFIILITGEFILGILGNGYIALVNWIDWIKKKKISTTDYILTNLVISRICLISVIVVNGIVTVLYPDVYTKSKLQIAISTFWTFANYLNMWFTTCLNVFYFLKIANSSHPLFLWLKQKIDMVVRWILLGCFAISLLVSLIIAIVLSRDYRFHAIAKHKRNITEMFHVSKMLYFEPLTLFNLLAIVPFIVSLMSFFLLVRSLQRHTKQIKLYATGGRDPSTEAHVRAIKTMTSFIFFFFLYYITSLLVTFSYLMTKYKLAMAFGEIVAILYPSGHSFILIILNNKLRQASVRMLTCIKITCVI
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 8, T2R8.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DRB1_HUMAN
Sequence: MVCLKLPGGSCMTALTVTLMVLSSPLALSGDTRPRFLWQPKRECHFFNGTERVRFLDRYFYNQEESVRFDSDVGEFRAVTELGRPDAEYWNSQKDILEQARAAVDTYCRHNYGVVESFTVQRRVQPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFLNGQEEKAGMVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS
What is the function of this protein?
(Microbial infection) Acts as a receptor for Epstein-Barr virus on lymphocytes.
What are the official names of this protein?
HLA class II histocompatibility antigen, DRB1 beta chain, Human leukocyte antigen DRB1, HLA-DRB1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Late endosome membrane; Single-pass type I membrane protein. Autolysosome membrane. Note=The MHC class II complex transits through a number of intracellular compartments in the endocytic pathway until it reaches the cell membrane for antigen presentation (PubMed:18305173). Component of immunological synapses at the interface between T cell and APC (PubMed:29884618).
Protein: SPR2H_MOUSE
Sequence: MSYQQQQCKQPCQPPPVCPPPQCPEPCPPPKCPEPCPPPKCTEPCPPPKCPEPCPPPKCPEPCPPPKCPEPCPPPKCTEPCPPPSYQQKCPSVQPSPPCQQKCPPKNK
What is the function of this protein?
Cross-linked envelope protein of keratinocytes.  It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase.  All that results in the formation of an insoluble envelope beneath the plasma membrane (By similarity).
What are the official names of this protein?
Small proline-rich protein 2H.
What is the protein family that this protein belongs to?
Belongs to the cornifin (SPRR) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGC_ACIB5
Sequence: MISVGIVGGTGYTGVELLRILLRHPKAQVRVLTSRTEAGKPVADMFPNLRGHTDLQFSDLNIDALKECDVVFFATPHGVAMQHAKDLIAAGTKVIDLAADFRLQNLEQFEKWYGMEHACPDVLKDSVYGLTELNREKIKQAQVIGNPGCYPTTVQLGLAPLLKSAQALIETKNIIIDAKSGVSGAGRKASLGMIYSENADNFKAYGVAGHRHHPEIVEALENIAGKKDVFEGLLFVPHLVPMIRGMLSTIYVDLTEAGKQTALQALYENFYANEKFVDVMPANSSPETRSVRGANELRIALYKPQPNKLIILAAQDNLVKGASGQAVQNMNLMFGFNEDEGLQGIGLLP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLAK_PIG
Sequence: MEVMNLIEQPIKVTEWQQTYTYDSGIHSGANTCVPSVSSKGLMEEDEACGRQYTLKKTTTYTQAVPQSQGDLEYQMSTTARAKRVREAMCPGVTGEDSSLLLATQVEGQTTNLQRLAEPSQLLKSAIVHLINYQDDAELATRALPELTKLLNDEDPVVVTKAAMIVNQLSKKEASRRALMGSPQLVAAVVRTMQNTSDLDTARCTTSILHNLSHHREGLLAIFKSGGIPALVRMLSSPVESVLFYAITTLHNLLLYQEGAKMAVRLADGLQKMVPLLNKNNPKFLAITTDCLQLLAYGNQESKLIILANGGPQALVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPAIVEAGGMQALGKHLTSNSPRLVQNCLWTLRNLSDVATKQEGLESVLKILVNQLSVDDVNVLTCATGTLSNLTCNNSKNKTLVTQNSGVEALIHAILRAGDKDDITEPAVCALRHLTSRHPEAEMAQNSVRLNYGIPAIVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQEASVIPRLVQLLVKAHQDAQRHVAAGTQQPYTDGVRMEEIVEGCTGALHILARDPMNRMEIFRLNTIPLFVQLLYSSVENIQRVAAGVLCELAQDKEAADAIDAEGASSPLMELLHSRNEGTATYAAAVLFRISEDKNPDYRKRVSVELTNSLFKHDPAAWEAAQSMIPINEPYADDMDATYRPMYSSDVPLDPLEMHMDMDGDYPMDTYSDGLRPPYPAADHMLA
What is the function of this protein?
Common junctional plaque protein.  The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue.  The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques.  Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells.  Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton (By similarity).
What are the official names of this protein?
Junction plakoglobin.
What is the protein family that this protein belongs to?
Belongs to the beta-catenin family.
What are the subcellular locations of this protein?
Cell junction, adherens junction. Cell junction, desmosome. Cytoplasm, cytoskeleton. Membrane; Peripheral membrane protein. Note=Cytoplasmic in a soluble and membrane-associated form.
Protein: TRUB_DINSH
Sequence: MGRRKKGRAVSGWIVIDKPAGLSSNAVVGKVRWAFDAQKAGHAGTLDPEATGVLAIALGEATKTVPFVTDALKAYEFTVRLGQATNTDDGEGEVTETSDARPSDDEIRAALPPFEGDILQVPPQFSAVKIDGERAYARARAGQEMEIAARPLYVDSLTFIARPDPDHVTLEMVCGKGGYVRSIARDLGRALGCFGHVKSLRRTWSGPFELSDATPLETLEDLAKDPALDAHLMPLETGLADLPELPCTPEGAARMRNGNPGMVRASDAEYGETAWASYNGTAVAVGTYRAGELHPTRVFQHGAL
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: FABZ_ALBFT
Sequence: MNRNTMDIYKILKQLPHRYPFLLVDRVLAIDKGKSIRAVKNVTINEPFFQGHFPYRPVMPGVLMLEALAQAAALLAFDAIDTTPDEDSVYYFAGMDGVRFKRPVEPGDQLILEVELVRMKAGIFKFKARALVDNELAVEAELTCAVRKIA
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMY_STRHY
Sequence: MQQRSRVLGGTLAGIVAAAAATVAPWPSQATPPGQKTVTATLFERKYVDVAKACTDQLGPAGYGYVEVSPASEHIQGGQWWTSYQPVSYKIAGRLGDRDAFASMVSACHAAGVKVIADAVVNHMAAGSGRHHAQYTKYNYPGFYQDQTFHGCRKSISDYTNRDDVQTCELVDLADLGTGSDYVRTTIAGYLGLRSLGVDGFRIDAAKHISATDLAAVKGKMKDPGFWVQEVIYGAGEAVRPDEYTGIGDVDEFRYGTHLKSAFQSGNIAQLKSVADGKLWQRQARTFVDNWDTERNGSTLTYKDGAAYTLANVFMLASPYGSPNVYSGYEWTDKDAAAGGSTGWTDDAAKREITGMVGFRNAVGSAELTNWWDNGGRPLAFARSDKGFVALNNGDAALTQTFATSLPAGTYCDVVHAASSCDGDTVTVGDTEAQVDAAKSVALHVGATGQSACRQAVALHVPGQSAGSPRSSAKRVEQ
What are the official names of this protein?
Alpha-amylase, 1,4-alpha-D-glucan glucanohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: TFLI_BPT5
Sequence: MQFVPIKDAPGYLVNEAGDVFSTFTNKVLSRYIVDGYPAVKLQINGKQTSVLIHRIISHVFGDLYNLFDPELEVDHKDRDRLNLSKDNLQVLSKIEHQRKTNKDNGWSDSRVPCPLCGSLMLQRSVTCTNCKPKPTGRLIKPELSLDDITEKVLLMGWVKAAKELEVSESTLRRRYTKLTGLSPKVLTEQRKSK
What is the function of this protein?
Endonuclease that cleaves only one strand of asymmetric DNA substrates thereby introducing interruptions into the template or coding strand.
What are the official names of this protein?
H-N-H endonuclease F-TflI, HNH endodeoxyribonuclease F-TflI, HNH endonuclease F-TflI.
Protein: TILS_RHOOB
Sequence: MLLPEEPAILEVRHAVRHWIAAHAPDGDVAVALSGGADSLALTAAAAVEARSAVALVVDHRLQRGSADVADGAAARARTLGCASAEVLPVDVTGSGGLEAAARQARYEALDAGRGTRPVLLGHTLDDQAETVLLGLSRGSGGRSIWGMSPYDSPWGRPLLGVRRAVTRQACTELGLDPHEDPHNSSPDFVRVRLRTEVLPLLEDVLGGGVAGALARTGEHLREEGAVLDAVAADAEAKVVVDGEIDAALLALSAPPVRRRVLRSWLLAAGARGLGDTQLRAVDDLVARWRGQGQVAVGGGTPDARLVVRRRRGRLNVGLDDRRRV
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.