PharMolix/UniProtQA huggingface dataset:
Protein: NUOK_RALSO
Sequence: MLSLAHYLVLGAVLFAISIVGIFLNRKNVIVLLMAIELMLLAVNMNFVAFSHYLGDLAGQVFVFFILTVAAAESAIGLAILVVLFRNLDTINVDDLDSLKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PAFB_MYCBO
Sequence: MATSKVERLVNLVIALLSTRGYITAEKIRSSVAGYSDSPSVEAFSRMFERDKNELRDLGIPLEVGRVSALEPTEGYRINRDAYALSPVELTPDEAAAVAVATQLWESPELITATQGALLKLRAAGVDVDPLDTGAPVAIASAAAVSGLRGSEDVLGILLSAIDSGQVVQFSHRSSRAEPYTVRTVEPWGVVTEKGRWYLVGHDRDRDATRVFRLSRIGAQVTPIGPAGATTVPAGVDLRSIVAQKVTEVPTGEQATVWVAEGRATALRRAGRSAGPRQLGGRDGEVIELEIRSSDRLAREITGYGADAIVLQPGSLRDDVLARLRAQAGALA
What is the function of this protein?
Does not seem to be involved in pupylation or substrate degradation.
What are the official names of this protein?
Protein PafB.
What is the protein family that this protein belongs to?
Belongs to the PafB family.
Protein: DISA_STRCO
Sequence: MAANDRAAAPGKSGGSAGADGLMRASLSAVAPGTSLRDGLERVLRGNTGGLIVLGSDKTVESMCTGGFVLDVEFTATRLRELCKLDGGIVLSSDLSKILRAGVQLLPDPTIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAAILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIAGVEPERELVVRDYVPEPTAKRSRTVDEALAELDKLSHAELLELSTVARALGYTGSPETLDSAVSPRGFRLLAKVPRLPGAIIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV
What is the function of this protein?
Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP).  c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation.  The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
What are the official names of this protein?
DNA integrity scanning protein DisA, Cyclic di-AMP synthase, c-di-AMP synthase, Diadenylate cyclase.
What is the protein family that this protein belongs to?
Belongs to the DisA family.
Protein: Y418_HAEIN
Sequence: MCKPQQKHYGRQVMNTQNSLKQVATATMVGTAIEYFDNYIYAMAAVLVFNHQFFHAVDPLSGQIAALSTLALTFIARPLGAILFGHFGDRFGRKNTFVMSLLLMGISTVVIGLLPTYDSIGIWATILLCLCRIGQGIGLGGEWGGAALVAVENAPEGKRGWYGTFPQLGAPLGLLLANGVFLGITAIFGQEAMTEWAWRIPFLSSVILVAIGLYVRLKLTEAPIFLAALNKPKPKRLPMLEVVTTHFKPFFLGMLVCIAGYVLFYIMIAFSQIYAKSAPTVSEAGYAMGLGFSPQIFTALLMASAVSLAITIAASGKYIDKIGRRTWLIWTTVGVAIFGLSLPLFLENGTTTSLFWFLFIGMGLIGMGYGPLASFLPELFPTHARYSGASLTYNIAGLFGASVAAIIALPLNAHYGLKGVGIYLTLNAVLSLVGLWFISETKDKLLS
What are the official names of this protein?
Putative metabolite transport protein HI_0418.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Metabolite:H+ Symporter (MHS) family (TC 2.A.1.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YE023_YEAST
Sequence: MAHSLLSCNGIPNFNPLSIKDSNIKRTKAGPEPTKAVAASMFFSGSSTYLPTWLINSLTSGFCSLETSAE
What are the official names of this protein?
Putative uncharacterized protein YER023C-A.
Protein: TUSA_COLP3
Sequence: MTTTIFQQTNHTLDAIGLRCPEPVMMVRMNIRKIASGETLLIKCDDPSTARDIPSFCRFMEHELLAKQTDTLPFLYVIKKN
What is the function of this protein?
Sulfur carrier protein which probably makes part of a sulfur-relay system.
What are the official names of this protein?
Sulfur carrier protein TusA.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_PROMA
Sequence: MGRTLESKKQIVEEIKGLLDKADMALVLDYQGLSIKEMSDLRSRLEQSSGICKVTKNTLMRKAINGDATWSGLESLLNGTNAFVLVKGDVGSALKAVQAFQKETKKSETKGGLYEGKLLTQDEIKAIAALPSKEALMAQIAGALNSITTKIAVGVNEIPSGLARSLKQHAENSES
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: ATPG_BRUA2
Sequence: MPSLKDLRNRIASVKATQKITKAMQMVAAAKLRRAQEAAEAARPYSQRMGAVLANIAQNVSGEDAPALMVGTGKDDVHLLVVCTAKRGLCGGFNSQIARLARDHARKLLAEGKTVKIITVGKKGADILRREFSALLHDHVDLREVKQLAFVHADQIGHKIIKLFEEGAFDVCTLFYSEFKSVISQVSTAQQLIPASADNEAEMETAGDAIYEYEPDPAAILSTLIPRNISVQIFRALLENVAGEMGAKMSAMDNATRNAGDMINKLSITYNRQRQAQITKELIEIISGAEAL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y1159_THEAC
Sequence: MITLPKISLIGSNIAKEGLEFVFAGPLAACSDCRVKNVCFNLEQGHRYRVTKVREQVNPCIIFNGDKVNTVEVEELEDYVNVQESKRIQEGAIITLKSMNCDYITCPNIEKCNLYYFKPDSKVMVKSIGKEIKCPKGYKMKQVAITYK
What are the official names of this protein?
UPF0179 protein Ta1159.
What is the protein family that this protein belongs to?
Belongs to the UPF0179 family.
Protein: MNMA_ACTSZ
Sequence: MTHSAILGSKTYNQYFPKLTPGQLAENGKIKVIVGMSGGVDSSVSAFILQQQGYQVEGLFMKNWEEDDDTDYCTAAADLADAQAVCDKLGIRLHKINFATEYWDNVFEHFLSEYKAGRTPNPDILCNKEIKFKAFLEYAAEDLGADYIATGHYVRRSGPDHDAHLLRGLDNNKDQSYFLHALSKKQVGQSLFPVGEVEKTVVRAVAEELGLITAKKKDSTGICFIGERKFKDFLARFLPAQPGDIKTTEGEVIGRHQGLMYHTLGQRKGLGIGGIKGKDENAWYVVEKDLKNNVLVVAQGHDNSALQSSGLIAKQLTWVSEQPLRKTLHCTVKTRYRQTDIACEVVPVNDDTVEVHFDEPQIAVTPGQSAVFYQGEECLGGGIIETQIK
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSB_HAEIN
Sequence: MSFTVIIPARFASSRLPGKPLADIKGKPMIQHVFEKALQSGASRVIIATDNENVADVAKSFGAEVCMTSVNHNSGTERLAEVVEKLAIPDNEIIVNIQGDEPLIPPVIVRQVADNLAKFNVNMASLAVKIHDAEELFNPNAVKVLTDKDGYVLYFSRSVIPYDRDQFMNLQDVQKVQLSDAYLRHIGIYAYRAGFIKQYVQWAPTQLENLEKLEQLRVLYNGERIHVELAKEVPAVGVDTAEDLEKVRAILAAN
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRH1_CAVPO
Sequence: MSFLPGMTPVTLSNFSWALEDRMLEGNSTTTPTRQLMPLVVVLSSVSLVTVALNLLVLYAVRSERKLHTVGNLYIVSLSVADLIVGAVVMPMSILYLHRSAWILGRPLCLFWLSMDYVASTASIFSVFILCIDRYRSVQQPLRYLRYRTKTRASATILGAWLLSFLWVIPILGWHHFMAPTSEPREKKCETDFYDVTWFKVMTAIINFYLPTLLMLWFYIRIYKAVRRHCQHRQLINSSLPSFSEMKLKLENAKVDTRRMGKESPWEDPKRCSKDASGVHTPMPSSQHLVDMPCAAVLSEDEGGEVGTRQMPMLAVGDGRCCEALNHMHSQLELSGQSRATHSISARPEEWTVVDGQSFPITDSDTSTEAAPMGGQPRSGSNSGLDYIKFTWRRLRSHSRQYTSGLHLNRERKAAKQLGCIMAAFILCWIPYFVFFMVIAFCKSCSNEPVHMFTIWLGYLNSTLNPLIYPLCNENFRKTFKRILRIPP
What is the function of this protein?
In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system.
What are the official names of this protein?
Histamine H1 receptor, H1R, HH1R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL24_BRUA2
Sequence: MQKIRKGDSVVVLSGKDKGRKGEVLKVMPKDEQALVSGINIVKRHQRQTQTQEAGIISKEAPIHLSNLAIADPKDGKPTRVGFRVEDGKKVRVAKRSGALIDG
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: SCRN1_BOVIN
Sequence: MAVAPPSYCFVAFPPRAKDGLVVFGKNSARPRDEVQEVVYFSAADHEPESKVECTYISINQVPRTHAIVISRPAWLWGAEMGANEHGVCIANEAINAREPAAETEALLGMDLVRLGLERGATAKEALDVIVALLEEHGQGGNYYEDANSCHSFQSAFLIVDREEAWVLETVGKYWAAEKITEGVKCICNQLSLTTKIDAEHPELRSYAQSQGWWMGEDEFNFSEVFSPADDHLTCCSGRDTLEKQEESITVQTMIDVLRDKASGVCVDSESFLTTASVVSVLPQNGSSPCIHYFTGTPDPSRSIFKPFIFVDDVKLVPKAQSPCFGDDDPAKKEPRFQEKPDRRHELYKAHEWARAVLESDEEQGQKLRKTMLELEKQGLEAMEEILTSSDPLDPTEVGDLFYDCVDTEIKFFK
What is the function of this protein?
Regulates exocytosis in mast cells.  Increases both the extent of secretion and the sensitivity of mast cells to stimulation with calcium.
What are the official names of this protein?
Secernin-1, p50.
What is the protein family that this protein belongs to?
Belongs to the peptidase C69 family. Secernin subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CKX8_ORYSI
Sequence: MELKAMYLYAAVLAVLLCSSVNFIQSPTDVLGPVALLEPTPSSARDFGAVVSDAPFAVMRPESPDDIALLLGALSSTAPSPRATVAAVGAGHSLHGQAQARDGIVVETRALPRDVHVVSARAHGGDDDATVRAYADVGAGALWVEVLEECLKLGLAPPSWTDYLYLTVGGTLSNGGISGQTFKHGPQISNVLQLEVVTGKGEVVTCSPTEIPELFFAVLGGLGQFGIITRARIPLQLAPPKVRWVRAFYDSFETFTGDQELLVSMPEQVDYVEGFMVLNEQSLHSSSVAFPAQLNFSPDFGSKGRKKVYYCIEFAVHDFQQDSSRADHVVKLVSAKLSYLRPHVYSVEVSYFDFLNRVRMEEESLRSRGLWDVPHPWLNVFVPKHGITQFKGLLMDTVSADDFEGPILVYPLLTDKWDGNTSAVVPAAPDGVMYIFGVLRSTDPARCGRACVDSIMARHRRVADEACRDGGGGGRGIGAKQYLARQPSPARWRDHFGAGWGRFAARKARFDPLHVLGPGQGIFPRTDSAGSM
What is the function of this protein?
Catalyzes the oxidation of cytokinins, a family of N(6)-substituted adenine derivatives that are plant hormones, where the substituent is an isopentenyl group.
What are the official names of this protein?
Cytokinin dehydrogenase 8, Cytokinin oxidase 8, OsCKX8.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: ENO2_DEBHA
Sequence: MAVTKLFARYVYDSRGNPTVEVDLTTDKGLFRSIVPSGASTGIHEALELRDGDKSKWLGKGVTKAVANVNELIAPAFVKANLDVTNQSAVDDFLNKLDGTPNKSKLGANAILGVSLATAKAAAAEKNVPLYQHLADISGSKQDKFVLPVPFQNVLNGGSHAGGALAFQEFMIVPTDAPTFSEALRMGSEVYHNLKSLTKKKYGQSAGNVGDEGGVAPDIGSPREALDLIMDAIDKAGYKGKIGIALDVAASEFYKDGKYDLDFKNPNSDESKWLSGEQLASLYEELINEYPIVSIEDPFGEDDWDAWVHFYSKVSSKVQIVGDDLTVTNPLRIKTAIEKKAANALLLKVNQIGSLTESIKAAQDSFDATWGVMVSHRSGETEDTFIADLSVGLRAGQIKTGAPARSERLAKLNQILRIEEELGDKAIYAGKNFHAASQL
What are the official names of this protein?
Enolase 2, 2-phospho-D-glycerate hydro-lyase 2, 2-phosphoglycerate dehydratase 2.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TVB41_HUMAN
Sequence: MGCRLLCCAVLCLLGAVPIDTEVTQTPKHLVMGMTNKKSLKCEQHMGHRAMYWYKQKAKKPPELMFVYSYEKLSINESVPSRFSPECPNSSLLNLHLHALQPEDSALYLCASSQ
What is the function of this protein?
V region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition (PubMed:24600447).  Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.  Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333).  Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.  In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.  The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462).  The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement.  This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells.  Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585).
What are the official names of this protein?
T cell receptor beta variable 4-1.
What are the subcellular locations of this protein?
Cell membrane.
Protein: MUTS2_PYRFU
Sequence: MKLRGDAREVYKRLLSRLESMIKLGEARTFLKKFEPTSDREEIIKRQNYLKEGLKNVRDDLEEYLLSIRPIRFRREFFHDRILLVSDEEVEEAEKLDLCPVTSDPSEIEDYPLILSTIGYGIEVEVKPSHIAPELYIIPLWENRDVLEALSKVFPGGAADKILISLKEIEEIFKKMEILENLDEIIVEKEKELNRKIEEKLERFKLTLSGRDLVEFMKALRAGNLEYLFHKFSALNDEIIEEINKAEKEISDVLGISVEIFPRDFPVEVPPEQIEALKRELEREFKIEFYLKSRETVEKILPHLQKLKEEIQKAYELYFLLVVKKFTRDFVFPEIVEEGIGFIEGRNLFIENPQPVSYFVGKSYGNFPGVEEANIVILTGANSGGKTSLLELISQIVILAHMGFPVPAKKAWFTVLDEIFFFKRKRSVYGAGAFETSLKGLVRAIKGKGKKLILIDEFESITEPGAAAKILAELLKIAYEKGFFVVIVSHLGEDLKREIPFARVDGIEAKGLDENLNLIVDRQPKFGVIGRSTPELIVERLARKGRGEEKMIMNRILKKFRK
What is the function of this protein?
Has ATPase and non-specific DNA-binding activities.  May be involved in recombination and/or recombinational repair.  Not involved in mismatch repair.
What are the official names of this protein?
DNA-binding protein MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily.
Protein: ELHA_APLCA
Sequence: MKANTMFIILCLSLSTLCVSSQSTSVHGKIFVPNRAVKLSSDGNYPFDLSKEDGAQPYFMTPRLRFYPIGKRAAGEMEQSEGQNPETKSHSWRKRSVLTPSLSSLGESLESGISKRISINQDLKAITDMLLTEQIQARRRCLDALRQRLLDLGKRDSDVSLFNGDLLPNGRCS
What is the function of this protein?
Injected in sexually mature animals califin A excites LB and LC cells of the abdominal ganglion and causes egg-laying.
What are the official names of this protein?
Atrial gland and califin peptides, ELH-18.
What is the protein family that this protein belongs to?
Belongs to the molluscan ELH family.
What are the subcellular locations of this protein?
Secreted.
Protein: RFC5_SCHPO
Sequence: MLWLDQYRPKTLASLDYHKQLSERLISLSSTNEFPHLLVYGPSGAGKKTRVVAILRELYGPGSEKLKIDQRTFLTPSSKKLQINIVSSLHHLEITPSDVGNYDRVIMQELLKDVAQSAQVDLQAKKIFKVVVINVADELTRDAQAALRRTMEKYSNNIRLILIANSTSKIIEPIRSRTLMVRVAAPTPEEIILVMSKILTAQGLEAPDSLLNNIANNCDRNLRKAILLLETVHAKSPGNKQLIDTGAQLPLPDWQTFIQQVGDSMLQEQSPARILAVRSMLYDLLSHCIPPTTILKELLSFFLSKVDTKLHPYLIQAAANYEHRTRMGNKSIFHLEAFVAYFMKVYAMLQLGMELPSY
What is the function of this protein?
The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins PCNA and activator 1.
What are the official names of this protein?
Replication factor C subunit 5, Replication factor C5.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CHMP5_DANRE
Sequence: MNRIFGRGKPKGPPPNLTDCISGVDSRAESVDKKIARLDAELMKYKDQMKKMRDGPSKNMVKQKAMRVLKQKRMYEGQRDQLMQQSFNMEQANYTIQTLKDTKTTVEAMKIGAKEMKKAYKNVKIDQIEDLQDQLEDMMEDANEVQEALSRSYGTPEIDEDDLEAELDALGDELLLDDDNSYLDEASSAPAIPEGAPGDRTTNRDGVLVDEFGLPQIPAT
What is the function of this protein?
Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs.  MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids (By similarity).
What are the official names of this protein?
Charged multivesicular body protein 5, Chromatin-modifying protein 5.
What is the protein family that this protein belongs to?
Belongs to the SNF7 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Endosome membrane; Peripheral membrane protein.
Protein: HIS4_CERSK
Sequence: MILYPAIDLKDGQCVRLLRGEMEAATVFGDDPAAQAAAFEAAGCEWVHLVDLNGAFAGRPVNAAAVEAILARIAVPAQLGGGIRDMATIALWLEKGLARVILGTVAVENPGLVREAARAFPGRVAVGIDARKGRVATKGWATETDVMATDLARSFEDAGVAAIIYTDIDRDGAMAGPNIEATDALARAVSIPVIASGGVSSLADLLALRDTGSIAGAISGRALYDGALDLTQALQALRT
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX307_LYCSI
Sequence: MKFVLLFGVLLVTLFSHSSAEMLDDFDQADEDELLSLIEKEEARAEECTPRFYDCSHDRHSCCRSELFKDVCTCFYPEGGDNEVCTCQQPKHLKYMEKAADKAKKFGGKIKKWFG
What are the official names of this protein?
U3-lycotoxin-Ls1v, Toxin-like structure LSTX-B7.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 01 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: T200B_HUMAN
Sequence: MTAGSPEECGEVRRSPEGRVSRLGRRLGRRRRPRSPPEPLRVRARLRLRSPSGAFAALGALVVLVGMGIAVAGYWPHRAGAPGSRAANASSPQMSELRREGRGGGRAHGPHERLRLLGPVIMGVGLFVFICANTLLYENRDLETRRLRQGVLRAQALRPPDGPGWDCALLPSPGPRSPRAVGCAEPEIWDPSPRRGTSPVPSVRSLRSEPANPRLGLPALLNSYPLKGPGLPPPWGPRTQTGHVIITVQPSGSCIEHSKSLDLGLGELLLGAPAARDCAHRSWPRLDRLSLGGYAKLGGGGDLGARV
What are the official names of this protein?
Transmembrane protein 200B, Transmembrane protein TTMA, Two transmembrane domain-containing family member B.
What is the protein family that this protein belongs to?
Belongs to the TMEM200 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GPMA_BRUMB
Sequence: MSRTLVLVRHGQSEWNLKNLFTGWRDPGLTEQGHAEAKAAGQRLKAAGLKFDIAYTSALSRAQVTCQHILDELGQPGLETIRDQALNERDYGDLSGLNKDDARAKWGEEQVHIWRRSYDVPPPGGESLKDTGARVWPYYLHTIQPHVLREETVLVAAHGNSLRALIMALEGLTPEQILKQELNTGVPIIYRLNADSTVASKEILSA
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: GABD2_MYCS2
Sequence: MPAPSAADFARLRSLVAIEDLDARQSRPIEEVFTGRELTTIPVGTAEDVAAAFAKARAAQRGWAHRPVAERAAIMERFRDLVAKNRDFLMDVAQAETGKARSAAQEEIVDMMLNARYYARQAVKLLAPKRVQGLLPGVVKTVVNHHPKGVVGVISPWNYPMALSISDSIPALLAGNAVVVKPDSQTPYCTLANAELLYEAGLPRDLFAVVPGPGSVVGTAIVENCDYLMFTGSTATGRTLAEQCGRRLIGFSAELGGKNPMIVTRGAKLDVAAKAATRACFSNAGQLCISIERIYVERAVADEFTAKFGEQVRSMRLAATYDFTADMGSLISEDQIKTVSGHVDDAKAKGATVIAGGNIRPDIGPRFYEPTVLTGVTDEMECARNETFGPVVSIYPVESVAEAIEKANDTEYGLNASVWAGSKTEGEAIAAQLQAGTVNVDEGYALAFGSTAAPMGGMKASGVGRRHGADGILKYTESQTVATSRVLNLDPPLGISGTLWQKAMTPMIRAVQKLPGR
What is the function of this protein?
Catalyzes the NADP(+)-dependent oxidation of succinate semialdehyde to succinate.  Although it has succinate semialdehyde dehydrogenase activity, is likely to act physiologically on a different aldehyde(s) (By similarity).
What are the official names of this protein?
Putative succinate-semialdehyde dehydrogenase [NADP(+)], SSADH, SSDH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: Y474_RICPR
Sequence: MKSVLLTRNIQENNETIQEINKYNLDLRYIHCSLIKYKTLDFNINILNNYSNIIITSKYAAHILADYNLKQDIWVVGNKTKQLLGKKVIYTANNIADLIQHFPTDLYKHTIYLSSNEITQDLPNKIARHIIYNVEYLNELPISIIQEFENIRYFSKPAYRNAFKANTIRATTAYKKVFNDPSLGSTYPLEVPLGKMSIDFILLYSQNSAKTLVRLLLQNNLLQYLQDSLVIAISLKVANIVRPFIKNVVYCDNQSPHDIIKLLYENAKI
What are the official names of this protein?
Uncharacterized protein RP474.
Protein: RL15_BUCCC
Sequence: MYLNSLSNSVYKKRSKKRICRGIGSGWGKTGGRGHKGQKSRSGGKIRKSFEGGQTPLYRRIPKFGFRSKKKKFFDEIRLFELDCFHNLKYINLSILKKINLINKNIKYVKIIKSGLINRPIIISGLSVTKGARLCIESAGGVVKS
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: DHC5_ALTCI
Sequence: MKTGHRTVLLFGDVTDPWIEGIDHVYVQAAKKPWIRSFLEDLFSAIKTETKAMDRVLQEGFKDSSSFQELAERYRHAGDDFGMAHAMMIYAIRAVVLLETLSREPHILDESRPRPEVIGISGGLFSAAVMSISINFETLYAACIEAGRVWSRLCNLTLVRSRAMEESPGTWGWAILGIPAADLGKTLEQFQSSMGIHCSKRAKVGVIGDRWSTVIGPPSVLELTLSECPNLKNLPKDELNIHALQHTLSVSNSDIDYIVGNSPLLETPLPPGYRIHGLDDDFPEANYAEWRHLLRASAYQTLSRPLDIVQAVSNLNAALGVSKDIDAKIIGPSSHTTYLVKCLQTAGKEVLIQNGFPASPQTSGTNDGIAIVGMAGKGPGSDDLEEFWNVILKGLDLHEEVPSDRFNLEEYYSPKHPPAGPGRCTMTCRHGCFMNNPGHFDSKFFHISPREAMLMDPAHRLFLMNAYEALEMAGYSNGQTKSTNPTKIATFFGQCNDDWHVVGHRALGCDAYTLQAVQRAFGPGRLAFQFNWEGPTYALDSACAATSSCIHLACMSLITRDIDMAVAGAANVLSTPHSFTSLSRSGVLSDSGNCKTYRDDADGYCRADFSGAVVLKRLDDAIAQNDNILAVISSSARNHSGNSTSITTSDAAAQERLFQKVLRNARVTPQDISYVEMHGTGTQVGDKAEIGAVSSVFSKRIDGRPLNVGAIKANIGHSEAAAGMSSLLKSILMFQNSTIPPQAGMPHTLNPNFPPLHEINIQIPSEPLEFKTTDNKPRRILLNNFDAAGGNACLLLEDYTDTKERNADVRSAHTIVMSARTQSSQLLNKKRLLRWLRSKPNTRVEDLAYTTTARRMHHPIRSAIIASTTQEVIAKLEAEIERNDSSLVQRASPLVFVFTGQGSHYGGMGSELYGSSPIFRERVDLCASICAGYDFPPFLDIITNETVNVSTKNASQVQLAVLTLEMALTHFWRSAGIEPTMVIGHSLGEYAALHAAGVLSLADALYLVGHRSLLLLERCESDSCSMLSVSMSVDEVQAQLTRIRSSCNVACINSSTSTVVSGTAEDLAEFQSSITAQNAKVRAKKLSLPFAFHSFQMDPILEDYSRIAAGVTYSAPKIPVASTLLGSVVNREGIFTQEYMVQQTRQAADFMGGLVAVKSELADPLWLEVGPAPVCMSFVRDTLSTPASKMTHSLQPKTSNWMSLSKTLAAMYTSGVDIDWLAFHAPYESDLKLLTLPSYAWDVRNFWITHTDNATEVVSEQSPVTSSEPLISTCAQYLVAKSSSPNIRVALRASIADPGFMGLMDGHKMQGIGLCSGSVFCEAAFAATKYALEYSGRKNITQPWLTLHDPKLLLPLTKKSVGPDGDLVTTAVMYSSSAETISITFQVTSASASYDLGTCVVKVRDPTRSQVEWDRISYFIKARMDETIKNAKEGRGHRMQPEVFYALFGNAVEFAPDFQGINEAYIAKDFQEAAAVVTLPHDPSGTRFTFSPYWGEALVHLAGFMVNGNPSKSPKTTFIVMGFASVEQTAPLIPGKQYMTYTRISKWVKDTAYCDAIVFDPESFTIVLQCVDIRYQELPRATWKHVLEGPHETPIVHAQRPPVRNSKKYVETRELQQPSSATVPAQETTIDEPEQQEGEPAAGARLFNAILDSISKATGTDPSEFRDDTMIADLGVDSIMAIEVVATVKDVSGLELPAAFVFEYPTIGDLRKEFRANEPTVENPRFSATPSSAEASIPSSPSSLAHPMSDSASSLSPSDREEALPLERQSMTKREQKRPVKIDDDASPEPVVRIMLLQGRPGSKRIPFYMMADGTGTIATYIHLPPFKSKMPVYGIDSPFLRCPKRLTKEVGIEGVAKLIVDALMKTQPEGPLMIGGFSAGSIVAYEVCRQLGRAGRQVEGLVLIDMCCPRSSLLDEDKMNSEDDASFAIFESAVTKDGLWSSSETTQQHFRAYHVAMHAYHPPYMLEEERPTRTAVIWAEKGMVNRVMGNEKLMKMLVEQGIPMTSYPGYMEDPKLGAFACLVPDRTKADLGPNGWEKYTAGEVLTLSVAGDHLDLPMPGHVHLLHAQMEKAFAYIKG
What is the function of this protein?
Highly reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of 10,11-dehydrocurvularin, a prevalent fungal phytotoxin with heat shock response and immune-modulatory activities (PubMed:26493380).  The highly reducing polyketide synthase Dhc3 is responsible for biosynthesis up to the tetraketide stage (PubMed:26493380).  The non-reducing polyketide synthase Dhc5 then conducts four additional chain extension cycles, producing the unreduced part of the nascent octaketide from C-1 to C-8 in 10,11-dehydrocurvularin (PubMed:26493380).
What are the official names of this protein?
Non-reducing polyketide synthase Dhc5, Dehydrocurvularin biosynthesis protein 5.