PharMolix/UniProtQA huggingface dataset:
Protein: ILVD_GLOVI
Sequence: MSGNLRSRIVTQGVQRSPNRAMLRAVGFGDGDFERPIVGVANGFSTITPCNLGLGALAERAEAALRAGGAMPQLFGTITISDGISMGTEGMKYSLVSREVIADSIETVCNGQSLDGVLAIGGCDKNMPGAMIAIARLNIPAVFVYGGTIKPGRYQDQDLTVVSAFEAVGQYSAGKIDQTTLVEIERRACPGAGSCGGMYTANTMSSAFEAMGMSLVYSSTMAAEDPEKADSTALSAKVLVEAIQAQILPSAILTRKAFENAIAVIMAIGGSTNAVLHLLAIAHSARVPLALDDFECIRARVPVLCDLKPSGRFVATDLHRAGGIPQVMKMLLVRGLLHGDALTVTGQTVAEVLRDVPTEPRTDQEVIRPWDRPLYSSGHLAILRGNLASEGAVAKITGVKKPQITGPARVFDSEESCMEAILAGAIQPGDVIVIRYEGPKGGPGMREMLSPTSAIIGAGLGDAVGLITDGRFSGGTYGMVVGHVAPEAFVGGTIALVEAGDLITIDAPARKIELLVTTDELERRRAAWRPPAPRYIRGVLAKYARQVNSSSLGAVTDAFI
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: MCES_YARLI
Sequence: MYDPARDCYQAEGESADARDAAEIAGGEFLADSATPETKSDSTKSDGNDPKQETSETKRPAYNYLPKIARKETTSGSRDAASAKPQLKRREREDVRVAGDRVAPRADMGSYVDYSEKESRERQDRDRDSRDHRDRDRDRDRGRDRYDSRDRDRYDSRDRPRDYDSRDRDRDRDRDRYDDRVRDYDSRERDRYDDRARDYDRGSRDSRDYRDRHDRERERYDSGNSRETRDVRESRERSLSPTREPKPHDPAAPAPSKQKRPSQRGGREAAAARAAQYRAEMEKREARAQAAAQQGDQVGDSLVRNHYNQAPERGVVARQSSPIIKLRNFNNFIKSVLIQKQSLGFGMRVIDMGCGKGGDLNKWSRQRVRDYIGVDIADVSVQQASERYHNMQPRPRFYAEFHVADAFGTPLIDIINPRAFPVDCISSQFAMHYAFATEELARSMLTNVSNSLCRDGVFLGTIPNSDKILEGIAGGLKESEPKEGEERYGYFGNSVYKVEFNTPPTKDQAFRPPFGHKYTFYLQDAINNVPEYVVPFEVFRALASDYNLELIYKKPFLEMFDEEVKNDLNMARLAERMKVFKEDGSLGIDGDQREACGFYLAFAFRKLGA
What is the function of this protein?
Responsible for methylating the 5'-cap structure of mRNAs.
What are the official names of this protein?
mRNA cap guanine-N7 methyltransferase, mRNA (guanine-N(7))-methyltransferase, mRNA cap methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NDPA_VIBVU
Sequence: MSLHLSNVILHQLSKNDQDELMVNYRSESLVNDSSTENLVAELHRVFHSKAGKGFGCFQSDSEFQIWLNELQRGELNFYDFSQKCAVRLKEELAKYPFADEGILVFAEYQSLATDYLFVGILPLNQSLKVTEGLDISATDYLDINKMDIAARIDLSVYEADKESNRYLSYIKGRVGRKVADFFLDFLQAEVGLDSKQQNQVLMQALDDFCTDAKLEKQEVNEYKKQVYEYCNGQIKAGEEVEIRELSGELPPSPSGASFLEFTQEQGYGLEESFPADRGLVRKLTKYVGAGGGLNVSFDSLLLGERIFYDPETDTLTIKGTPPNLRDQLTRNR
What are the official names of this protein?
Nucleoid-associated protein VV1_3120.
What is the protein family that this protein belongs to?
Belongs to the YejK family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: TSAC_BUCAI
Sequence: MLHNDDVIAYPTESMFGLGCDPNSKKAVKKLLNLKNRSIEKGLILVASDFDQIKMYVNENILSNKQKKKIFFHWPGPFTFLLPAKPNTPYWLTGKFNTVAVRVSAHFEIIKLCNAFGQAVVSTSANISNMTPCFTSEEVFKCFGKDFPLLNGKIGNEKNPSKIINIINGKLIRYV
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTJ_ECO81
Sequence: MYIYWILLGLAIATEITGTLSMKWASVSEGNGGFILMLVMISLSYIFLSFAVKKIALGVAYALWEGIGILFITLFSVLLFDESLSLMKIAGLTTLVAGIVLIKSGTRKARKPELEVNHGAV
What is the function of this protein?
Catalyzes the excretion of spermidine.
What are the official names of this protein?
Spermidine export protein MdtJ.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtJ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CNTA_ACICP
Sequence: MSAVEKLPEDFCANPDVAWTFPKVFYTSSQVFEHEKEAIFAKSWICVAHGSELAQPNDYITRKVIGENIVIIRGKDSVLRAFYNVCPHRGHELLSGSGKAKNVITCPYHAWTFKLDGSLALARNCDHVESFDKENSSMVPLKVEEYAGFVFINMDENATCVEDQLPEFAERLNQACSVIKDLKLAARFVTETPANWKVIVDNYLECYHCGPAHPGFADSVQVDKYWHTTHQNWTLQYGFARSSEKSFKLDPSVTDPEFHGFWTWPCTMFNVPPGSNFMTVIYEFPVDAETTLQHYDIYFTNEELTQDQKDLIEWYRNVFRPEDLNLVESVQRGLKSRGYRGQGRIMTDKQRSGISEHGIAYFQHLVAQHHK
What is the function of this protein?
Converts carnitine to trimethylamine and malic semialdehyde.  Acts on both enantiomers.
What are the official names of this protein?
Carnitine monooxygenase oxygenase subunit, Carnitine monooxygenase alpha subunit.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family. CntA subfamily.
Protein: EEIG1_HUMAN
Sequence: MAFLMKKKKFKFQTTFTLEELTAVPFVNGVLFCKVRLLDGGDFVSLSSREEVQENCVRWRKRFTFVCKMSANPATGLLDPCVFRVSVRKELKGGKAYSKLGFADLNLAEFAGSGSTVRCCLLEGYDTKNTRQDNSILKVTIGMFLLSGDPCFKTPPSTAKSISIPGQDSSLQLTCKGGGTSSGGSSTNSLTGSRPPKARPTILSSGLPEEPDQNLSSPEEVFHSGHSRNSSYASQQSKISGYSTEHSRSSSLSDLTHRRNTSTSSSASGGLGMTVEGPEGSEREHRPPEKPPRPPRPLHLSDRSFRRKKDSVESHPTWVDDTRIDADAIVEKIVQSQDFTDGSNTEDSNLRLFVSRDGSATLSGIQLATRVSSGVYEPVVIESH
What is the function of this protein?
May play a role in estrogen action.
What are the official names of this protein?
Early estrogen-induced gene 1 protein, EEIG1.
What is the protein family that this protein belongs to?
Belongs to the EEIG family.
Protein: AIM23_YEAS7
Sequence: MLKVPLSDVLSQKMLFLKSFRYFHCTKYFSRDNASSTTDIFRNAMKRKRELANLKEQSHGNVARNAAFPKEYIKRPKQVPRNATNRKKILITWSTGTDRAKEAANSVVSEIFKKNHKGNIKVVDPTTHRIEPSNIRYFAKGIDLDKVGLSIVNVEQIDNENQIPLVKIVESRVALKKYSDFLAKKKEKELMELGVLNKSYKNLVTDKKEDNLKHIKISWQIESDDLKRQKAHEIVSLLKKGNKVTLYLDDKNNINSNNWLENFEELDRSQKGEPPRLPESVFQKRAAVLETLKEIVSEYANDPVLLGNMNSKMIMKLIPKDVKPQNNDKRALKELRKKERQEKLQKRIQRKKMNEM
What are the official names of this protein?
Altered inheritance of mitochondria protein 23, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AIM23 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NDL1A_DANRE
Sequence: MDADMIPKFTTKEEEIDFWKALSLKYKKSYKEAQEELLEFQEGSRELETELETQLGQAEHRIRDLQADNQRLQHELDSLKEKLEYQYAQSYKQISVLEDDLSQTRGIKEQLHKYVRELEQANDDLERAKRATITSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRDTRSEVTRMSAPSSPTPDNDKTDSAVQASLSLPATPLSKNLDNAFTSQTVLANGSTNAALTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQAARKNYVTNVNGNLINGDISNYSHSLHTSYFDKARTVNGLDPGDGTHITAPPRSNSPSGLVLSV
What is the function of this protein?
Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome.  Positively regulates the activity of the minus-end directed microtubule motor protein dynein.  May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end (By similarity).
What are the official names of this protein?
Nuclear distribution protein nudE-like 1-A.
What is the protein family that this protein belongs to?
Belongs to the nudE family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Localizes to the interphase centrosome and the mitotic spindle.
Protein: FIEF_SALA4
Sequence: MNQTYGRLVSRAAIAATAMASALLLIKILAWWYTGSVSILAALVDSLVDIAASLTNLLVVRYSLQPADDEHTFGHGKAESLAALAQSMFISGSALFLFLTSIQNLIKPTPMNDPGVGIGVTVIALICTIILVTFQRWVVRKTQSQAVRADMLHYQSDVMMNGAILIALGLSWYGWHRADALFALGIGIYILYSALRMGYEAVQSLLDRALPDAERQEIIDIVTSWPGVSGAHDLRTRQSGPTRFIQIHLEMEDNLPLVQAHFVADQVEQAILRRFPGSDVIIHQDPCSVVPREGRKFELV
What is the function of this protein?
Divalent metal cation transporter which exports Zn(2+), Cd(2+) and possibly Fe(2+).  May be involved in zinc and iron detoxification by efflux.
What are the official names of this protein?
Cation-efflux pump FieF.
What is the protein family that this protein belongs to?
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS9_BACFR
Sequence: MEVVNALGRRKRAIARVFVSEGTGKITINKRDLAEYFPSTILQYVVKQPLNKLGVAEKYDIKVNLCGGGFTGQSQALRLAIARALVKINAEDKPALRSEGFMTRDPRSVERKKPGQPKARRRFQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: NUOA_DESRM
Sequence: MSDWIGVALFIVVGIVFGAGGMLTSFLIHPRSKNKFKLETYECGLPTEGATWVRFKTQYFTYALMFVIFDVEVIYLYPWAVSFVDLGLAGLIKMFLFIFILVLGLWYAWKEGALEWK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: M2_I68A5
Sequence: MSLLTEVETPIRNEWGCRCNDSSDPLVVAASIIGILHFILWILDRLFFKCIYRFFKHGLKRGPSTEGVPESMREEYRKEQQSAVDADDSHFVSIELE
What is the function of this protein?
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry.  After attaching to the cell surface, the virion enters the cell by endocytosis.  Acidification of the endosome triggers M2 ion channel activity.  The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur.  Also plays a role in viral proteins secretory pathway.  Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation.
What are the official names of this protein?
Matrix protein 2, Proton channel protein M2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses matrix protein M2 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type III membrane protein. Note=Abundantly expressed at the apical plasma membrane in infected polarized epithelial cells, in close proximity to budding and assembled virions. Minor component of virions (only 16-20 molecules/virion).
Protein: CMOA_PHOPR
Sequence: MRMAGQDNIFAAPIEKLGDFTFDQKVAEVFPDMIQRSVPGYSNIISAIGMLAERFAKPHSKIYDLGCSLGAATLSMRRSIQQEGCEIIAVDNSAAMVERCRLHIDAYRSDTPVQVVEADIRNIDIADASVVVLNFTLQFLVPEDRQMLLEKIYAGLRPGGILILSEKYIFDDEQAHELLINLHHDFKRANGYSELEISQKRSAIENVMRPDSIDTHKKRLTEIGFSSTEVWFQCFNFGSMFAIK
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: PEPE_CITK8
Sequence: MELLLLSNSTLPGKAWLEHALPLVAEQLHGRRSAVFLPFAGVTQTWDDYTAKTAAVLAPLGVSVTGIHSVADPVAAIADAEVVIVGGGNTFQLLKESRERGLLAPIVAAVKRGALYIGWSAGANLACPTIRTTNDMPIVDPQGFDALGLFPLQINPHFTNALPEGHKGETREQRIRELLVVAPELTVIGLPEGNWIQVSKGQATLGGPNTTYVFNAGEEAVPLEAGHRF
What is the function of this protein?
Hydrolyzes dipeptides containing N-terminal aspartate residues.  May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids.
What are the official names of this protein?
Peptidase E, Alpha-aspartyl dipeptidase, Asp-specific dipeptidase, Dipeptidase E.
What is the protein family that this protein belongs to?
Belongs to the peptidase S51 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1345_STRP4
Sequence: MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDSYKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK
What are the official names of this protein?
UPF0223 protein SPG_1345.
What is the protein family that this protein belongs to?
Belongs to the UPF0223 family.
Protein: CPSF6_DANRE
Sequence: MADGVDHIDIYADVEEEFNQESDYPVHDQIDLYDDVISPSANNGDAPEDRDYLDSLPAPGGNEGSKGAPANVVYTYNGKRIALYIGNLTWWTTDEDLTDAIRSIGINDVLEIKFFENRANGQSKGFALVCVGSDSSSRKLMDLLSKRELHGQNPIVTPCNKQSLSQFEMQSRKSTQSGQMSGEGKAGPPGSGSRGGGFPPGKGQRRFPGPPGQGDRFPGPVGPGGPPPHFPGMQGPPRLPSGPPGPLGPPGPPPPGQGLPPPLGGPPNRGDRPPPPVLFPGQFGQPPMGPMPPGPPPPGYGPPPGPPPPQQGPPPPGPFPPRPPGPLGPPLGLAPPPHMQGPPPGGPPPAPHVNPAFFPPPGNNMPSSDGRGPPPGDPYGRPPPYDRDFPGGRDMDASRTPLSEAEFEEIMNRNRAISSSAISRAVSDASAADYGSAIETLVTAISLIKQSKVSADDRCKVLISSLQDCLHGIESKSYGSVAGRRERSRERDHSRSREKSRRHKSRSRDRHEDYYRERSRERDRHRERDRDRERDREREREYRHR
What is the function of this protein?
Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs.  CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals).  Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation.  The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.  Plays a role in mRNA export.
What are the official names of this protein?
Cleavage and polyadenylation specificity factor subunit 6.
What is the protein family that this protein belongs to?
Belongs to the RRM CPSF6/7 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleoplasm. Nucleus speckle. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm.
Protein: PG045_MONPV
Sequence: MLSMFMYNNIIDYVHVHDIEDEASDNDDRDYVYPLPENMVYRFDKSTNILDYLSTERDHVMMAVQYYMSKQRLDDLYRQLPTKTRSYVDIINTYCDKVNNDYNSDMNIMCDMASTESFTVYDINNEVNTILMNNKGLGVRLATISFITELGRRCMNPVETIKMFTLLSHTICDDYFVDYITYISAPRDNAIHSTREYLKIMGIAVIMFATYKTLKYMIG
What is the function of this protein?
Plays a role in evading host innate immune response by inhibiting host inflammasome activation.  Interacts with and inhibits NLR-mediated interleukin-1 beta/IL1B production in infected cells.  At the host mitochondria outer membrane, interacts with the BH3 domain of host BAK and prevents BAK from binding active BAX.  In turn, host apoptosis is inhibited.
What are the official names of this protein?
Apoptosis regulator OPG045, Protein F1.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG045 family.
Protein: U76E6_ARATH
Sequence: MEKMEEKKRIVLVPVPAQRHVTPMMQLGTALNMKGFSITVVEGQFNKVSSSQNFPGFQFVTIPDTESLPESVLERLGPVEFLFEINKTSEASFKDCIRQSLLQQGNDIACIIYDEYMYFCGAAAKEFNLPSVIFSTQSATNQVSRCVLRKLSAEKFLVDMEDPEVQETLVENLHPLRYKDLPTSGVGPLDRLFELCREIVNKRTASAVIINTVRCLESSSLKRLQHELGIPVYALGPLHITVSAASSLLEEDRSCVEWLNKQKPRSVVYISLGSVVQMETKEVLEMARGLFNSNQPFLWVIRPGSIAGSEWIESLPEEVIKMVSERGYIVKWAPQIEVLGHPAVGGFWSHCGWNSTLESIVEGVPMICRPFHGEQKLNALCLESIWRIGFQVQGKVERGGVERAVKRLIVDEEGADMRERALVLKENLKASVRNGGSSYNALEEIVNLM
What are the official names of this protein?
UDP-glycosyltransferase 76E6.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: LUTB_GEOSW
Sequence: MAMKIDGANFHERVETNLHNTFMRGAVAGAQERLHTRRLEAAEELGNWEEWRALGEEIRQHTLENLDYYLMQLSENVAKRGGHVFFAQTAEEANNYIRNVVIQKNAKKIVKSKSMVTEEINLNAVLEAAGCEVIETDLGEYILQVDDHDPPSHIVAPALHKNKEQIRDVFRQKLGYKQTEKPEELALHARKMLRHEYLTADIGITGCNFAIAESGSITLVTNEGNADLVTALPKTQITVMGMERIVPTFEEMEVLVSLLTRSAVGQKLTSYITVLTGPRDEGDVDGPEEFHLVIVDNGRSNILGTEFQPVLQCIRCAACVNVCPVYRHIGGHSYGSIYSGPIGAVLSPLLGGYDDYKELPYASSLCAACTEACPVKIPLHELLLKHRQVIVEREGKAPISEKLAMKAFGLGASSSFLYKLGSKVAPSALTPFTNDDRISKGPGPLKAWTEIREFPAPNKERFRDWFREHQKGGEK
What is the function of this protein?
Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source.  Has probably a role as an electron transporter during oxidation of L-lactate.
What are the official names of this protein?
Lactate utilization protein B.
What is the protein family that this protein belongs to?
Belongs to the LutB/YkgF family.
Protein: GP_SINV
Sequence: MVGWVCIFLVVLTTATAGLTRNLYELKIECPHTVGLGQGYVTGSVEITPILLTQVADLKIESSCNFDLHVPATTTQKYNQVDWTKKSSTTESTNAGATTFEAKTKEINLKGTCNIPPTTFEAAYKSRKTVICYDLACNQTHCLPTVHLIAPVQTCMSVRSCMIGLLSSRIQVIYEKTYCVTGQLIEGLCFIPTHTIALTQPGHTYDTMTLPVTCFLVAKKLGTQLKLAVELEKLITGVSCTENSFQGYYICFIGKHSEPLFVPTMEDYRSAELFTRMVLNPRGEDHDPDQNGQGLMRIAGPVTAKVPSTETTETMQGIAFAGAPMYSSFSTLVRKADPEYVFSPGIIAESNHSVCDKKTVPLTWTGFLAVSGEIEKITGCTVFCTLAGPGASCEAYSETGIFNISSPTCLVNKVQKFRGSEQRINFMCQRVDQDVVVYCNGQKKVILTKTLVIGQCIYTFTSLFSLIPGVAHSLAVELCVPGLHGWATTALLITFCFGWLLIPAVTLIILKILRLLTFSCSHYSTESKFKVILERVKVEYQKTMGSMVCDICHHECETAKELETHKKSCPEGQCPYCMTITESTESALQAHFAICKLTNRFQENLKKSLKRPEVRKGCYRTLGVFRYKSRCYVGLVWGILLTTELIIWAASADTPLMESGWSDTAHGVGIIPMKTDLELDFALASSSSYSYRRKLVNPANQEETLPFHFQLDKQVVHAEIQNLGHWMDGTFNIKTAFHCYGECKKYAYPWQTAKCFFEKDYQYETSWGCNPPDCPGVGTGCTACGVYLDKLRSVGKAYKIVSLKYTRKVCIQLGTEQTCKHIDVNDCLVTPSVKVCMIGTISKLQPGDTLLFLGPLEQGGIILKQWCTTSCVFGDPGDIMSTTSGMRCPEHTGSFRKICGFATTPTCEYQGNTVSGFQRMMATRDSFQSFNVTEPHITSNRLEWIDPDSSIKDHINMVLNRDVSFQDLSDNPCKVDLHTQSIDGAWGSGVGFTLVCTVGLTECANFITSIKACDSAMCYGATVTNLLRGSNTVKVVGKGGHSGSLFKCCHDTDCTEEGLAASPPHLDRVTGYNQIDSDKVYDDGAPPCTIKCWFTKSGEWLLGILNGNWVVVAVLIVILILSILLFSFFCPVRSRKNKAN
What is the function of this protein?
Forms homotetramers with glycoprotein N at the surface of the virion (By similarity).  Attaches the virion to host cell receptors including integrin ITGAV/ITGB3 (Probable).  This attachment induces virion internalization predominantly through clathrin-dependent endocytosis (By similarity).  Class II fusion protein that promotes fusion of viral membrane with host endosomal membrane after endocytosis of the virion (By similarity).
What are the official names of this protein?
Envelopment polyprotein, M polyprotein.
What is the protein family that this protein belongs to?
Belongs to the hantavirus envelope glycoprotein family.
What are the subcellular locations of this protein?
[Glycoprotein N]: Virion membrane; Multi-pass membrane protein. Host cell surface. Host Golgi apparatus membrane; Multi-pass membrane protein. Host endoplasmic reticulum membrane; Multi-pass membrane protein. Host mitochondrion. Note=Interaction between glycoprotein N and glycoprotein C is essential for proper targeting of glycoprotein N to the host plasma membrane complex, where virion budding occurs. SUBCELLULAR LOCATION: [Glycoprotein C]: Virion membrane; Single-pass type I membrane protein. Host cell surface. Host Golgi apparatus membrane; Single-pass type I membrane protein. Host endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=Budding probably takes place at the host plasma membrane (Probable). Glycoprotein C cytoplasmic tail is important for efficient Golgi localization (By similarity).
Protein: COR1B_HUMAN
Sequence: MSFRKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAFLVLPLSKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFSRMSERQLALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITEEPPYIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQDDLYPDTAGPEAALEAEEWVSGRDADPILISLREAYVPSKQRDLKISRRNVLSDSRPAMAPGSSHLGAPASTTTAADATPSGSLARAGEAGKLEEVMQELRALRALVKEQGDRICRLEEQLGRMENGDA
What is the function of this protein?
Regulates leading edge dynamics and cell motility in fibroblasts.  May be involved in cytokinesis and signal transduction (By similarity).
What are the official names of this protein?
Coronin-1B, Coronin-2.
What is the protein family that this protein belongs to?
Belongs to the WD repeat coronin family.
Protein: TRUD_PICTO
Sequence: MFYINIAYIFMDLGMYGYITKTEKLNGMIKSNPEDFIVEEIPFDIKKDDNGKYLIIKARLYDWDTNRFVMYLARHMNISRKRITYAGTKDKRAVTTQYFCINTDRMFSGSINGIEIIEQFRSNDIIKLGDLYGNRFLIKVDYPGDLEKDSSETLKEINEKGGFPNFFGVQRFGSMRSNTHYIGKMIIKGEYEKAADKYLYDDNFDTEEYRINYGKNMDAKNSLKEYPGNLTFERSILGAIASGNKSSAFNALPKNLSIMFVHAFQSYLFNKMLSERMKHVKDLKTVIEGDLLYNIDDYFNPDKKRLIEANRYNLEMLNNLSSMDKIRPVIPLPGFDTRMPDGLQRDIMLKVLEDENVSLQDFKIPGEYSYMSSSGDYRIISAKPINLKFPEKNKLDFILGRGIYATSFLREIIK
What is the function of this protein?
Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
Probable tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: CH10_AERS4
Sequence: MKIRPLHDRVIIKRIEAEAKSAGGIVLTGTAAQKSTRGEVLAVGTGRILDNGDVKALAVKVGDKVIFNEGYGVKTEKLDGQDVLILSETDILAIVEA
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBFA_XANC5
Sequence: MPTKSFHRTDRVSAQVRRDLGTIVHAAVRDHGLPSVSVSDVEISRDLAHAKVFVTALQQERSAEAVKGLKEIAGQLRTQLARAMKLRHVPELHFHYDDSVDRGERIDNLLRDLDDVGPEATSSDEDAEQR
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCD_CLOK5
Sequence: MLNKFFKKTKYITVSQRALGDIHDDFTKKPSIPNGMWVKCDGCGKVLYKNDMEKNNKVCYHCGYHFRMNALERLELILDKESFYEFDKDITAANPIEFKGYEDKIKNMQNKTNIKEAVITGKGTIGREEAVVCIMDSNFMMGSMGSVVGEKITRAVEKSIELKLPLIIFTTSGGARMQEGIFSLMQMAKVSGAISRLNEEGLLYLSVLTDPTTGGVTASFAMIGDIILAEPGALIGFAGKRVIEQTIKQKLPEGFQKAEFLLQHGFIDNIVSRENLKETLRKILVIHGRGN
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.