PharMolix/UniProtQA huggingface dataset:
Protein: GRM3_RAT
Sequence: MKMLTRLQILMLALFSKGFLLSLGDHNFMRREIKIEGDLVLGGLFPINEKGTGTEECGRINEDRGIQRLEAMLFAIDEINKDNYLLPGVKLGVHILDTCSRDTYALEQSLEFVRASLTKVDEAEYMCPDGSYAIQENIPLLIAGVIGGSYSSVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFYQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFEQEARLRNICIATAEKVGRSNIRKSYDSVIRELLQKPNARVVVLFMRSDDSRELIAAANRVNASFTWVASDGWGAQESIVKGSEHVAYGAITLELASHPVRQFDRYFQSLNPYNNHRNPWFRDFWEQKFQCSLQNKRNHRQVCDKHLAIDSSNYEQESKIMFVVNAVYAMAHALHKMQRTLCPNTTKLCDAMKILDGKKLYKEYLLKINFTAPFNPNKGADSIVKFDTFGDGMGRYNVFNLQQTGGKYSYLKVGHWAETLSLDVDSIHWSRNSVPTSQCSDPCAPNEMKNMQPGDVCCWICIPCEPYEYLVDEFTCMDCGPGQWPTADLSGCYNLPEDYIKWEDAWAIGPVTIACLGFLCTCIVITVFIKHNNTPLVKASGRELCYILLFGVSLSYCMTFFFIAKPSPVICALRRLGLGTSFAICYSALLTKTNCIARIFDGVKNGAQRPKFISPSSQVFICLGLILVQIVMVSVWLILETPGTRRYTLPEKRETVILKCNVKDSSMLISLTYDVVLVILCTVYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCISVSLSGFVVLGCLFAPKVHIVLFQPQKNVVTHRLHLNRFSVSGTATTYSQSSASTYVPTVCNGREVLDSTTSSL
What is the function of this protein?
G-protein coupled receptor for glutamate.  Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors.  Signaling inhibits adenylate cyclase activity.
What are the official names of this protein?
Metabotropic glutamate receptor 3, mGluR3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AROK_BRADU
Sequence: MSDAALPIQASPEADILSALGARSIVLVGMMGVGKSTIGRRMAARLKLPFVDADTEIEAAAGMTIPEIFERHGEGHFRDGEARVIARLLDGGPVVLATGGGAFMREETRARIAAKAVSIWLKADHDVIMRRVRRRADRPLLQTADPEGTVTRLLTEREPVYSHADLTIASRDVPHDKIVEECIETLRAHLCGEQAAQPPADVASAVR
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABV2_VIBVU
Sequence: MRIEPIIQGVVARSAHPFGCEAAIKKQIAFVKNAPQISQGPKRVLILGASSGFGLAARIALTFGGAQADTIGVSFERGPSEKGTGSAGWYNNVFFKREAEKEGRIAINIVGDAFASETRTQVIEAIETYFEGEVDLVIYSLATGMRPISNQPGEFWRSVIKPFGQTVTGASFDLEHDRWIDTTLESATEEEALHTIKVMGGEDWESWIDTLINAESIAQGCQTIAFSYVGPEITHPIYLDGTLGRAKIDLHQTSHSLNLKLANFDGAAYATVCKALVTKASVFIPALSPYLLALYRVMKDEKCHEGCIEQMQRLFATKLYGQDHISVDGERLVRMDDWELAPHIQNKVNQILEEMDANNFQVIGDYQGFKNEFLQLNGFGFDEVDYSQDIDLQTILKLTP
What is the function of this protein?
Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II).  Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH] 2, ENR 2.
What is the protein family that this protein belongs to?
Belongs to the TER reductase family.
Protein: RBSK_BACSU
Sequence: MRNICVIGSCSMDLVVTSDKRPKAGETVLGTSFQTVPGGKGANQAVAAARLGAQVFMVGKVGDDHYGTAILNNLKANGVRTDYMEPVTHTESGTAHIVLAEGDNSIVVVKGANDDITPAYALNALEQIEKVDMVLIQQEIPEETVDEVCKYCHSHDIPIILNPAPARPLKQETIDHATYLTPNEHEASILFPELTISEALALYPAKLFITEGKQGVRYSAGSKEVLIPSFPVEPVDTTGAGDTFNAAFAVALAEGKDIEAALRFANRAASLSVCSFGAQGGMPTRNEVEELLS
What is the function of this protein?
Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium.  The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
What are the official names of this protein?
Ribokinase, RK.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYY_BURL3
Sequence: MSTEPSSKPVFPITDEVRHALAVTKRGVDELLVEEEFAQKLARSAATGTPLRIKLGLDPTAPDIHIGHTVVLNKMRQLQDLGHTVIFLIGDFTSLIGDPSGRNATRPPLTREQIESNAKTYFEQAALVLDRDKTEIRYNSEWSMPLGADGMIKLASRYTVARILEREDFTKRFQGGVPISIHEFLYPLMQGYDSVALNADLELGGTDQKFNLLVGRELQKQYGQEQQCILTMPLLEGLDGVEKMSKSKGNYVGISEQPTDMFGKLMSISDTLMWRYFELLSFRPMDEIGGFKREIEGGRNPRDFKVLLAQEIVARFHSQADAERALEDFNHRAKGGVPDDIPSVTLAGAPLAIGQLLKQAGLVPSTSEALRNIEQGGVKIDGATVSDKGLKVEAGEFVVQVGKRRFARVTLTA
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EGLB_ASPFN
Sequence: MKFRNLFFAAVAGSAVAAPLAKEQKKRDSVFQWIGANESGAEFGENNLPGVWGTDYIFPDVSAITTLIDKGMNIFRIQFKMERLVPDSMTGAYDEAYLQNLTTVVNAVTDAGVHAILDPHNYGRFNGEIMSTPSDFQTFWKNLAGQFQSNSLVIFDTNNEYHDMDQELVLNLNQAAIDGIREAGATEQYIFVEGNSYTGAWTWTDVNDNMKNLEDPQDKIVYQMHQYLDSDGSGTSETCVSGTIGQERVTSATQWLKDNKKVGIIGEFAGGNNDQCKTAVKGMLDYLAENTDVWKGALWWAAGPWWGDYMYSLEPPNGVAFTGMLDVLQAYLG
What is the function of this protein?
Has endoglucanase activity on substrates containing beta-1,4 glycosidic bonds, like in carboxymethylcellulose (CMC), hydroxyethylcellulose (HEC) and beta-glucan.  Involved in the degradation of complex natural cellulosic substrates (By similarity).
What are the official names of this protein?
probable endo-beta-1,4-glucanase B, Endoglucanase B, Carboxymethylcellulase B, Cellulase B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
What are the subcellular locations of this protein?
Secreted.
Protein: FNRR1_ARATH
Sequence: MALSTTPSQMSVALPTRIDGSSRSMIKVQSISFTDKSWGPPLLRLDSKSRSLGVKKRSTICMSLQQSSKSKVLVTPLELEDPKETPLNLFRPKEPYTATIVSVERIVGPQAPGETCHIVIDHDGNVPYWEGQSYGVIPPGENPKKPGAPHNVRLYSIASTRYGDSFDGKTASLCVRRAIYYDPETGKEDPSKAGVCSNFLCNAKPGDKVKITGPSGKVMLLPEDDPKATHIMIATGTGVAPYRGYLRRMFMENVPNFKFDGLAWLFLGVANSDSLLYDEEFAGYRKDYPENFRYDKALSREEKNKKGGKMYVQDKIEEYSDEIFKLLDNGAHIYFCGLKGMMPGIQDTLKRVAEERGESWEQKLTQLRKNKQWHVEVY
What is the function of this protein?
Maintains the supply of reduced ferredoxin under non-photosynthetic conditions.
What are the official names of this protein?
Ferredoxin--NADP reductase, root isozyme 1, chloroplastic, Root FNR 1, AtRFNR1.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RR18_PHAAO
Sequence: MDKSKQPFRKSKRSFRRRLPPIGSGDQIDYRNMSLISRFLSEQGKILSRRTNRLTLKQQRLITIAIKQARILSLLPFRNNEKQLERVESIPRTTGPRTKNK
What are the official names of this protein?
30S ribosomal protein S18, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HM33_CAEEL
Sequence: MQLNSSSFHPHHFTCDTTRYSEEQVACICEALSNDARKLSQFVWTVLERDEMRNNQYILKAQAFLAFHSNNFKELYRIIESHHFASEHHLPLQEWWLNAHYHEAEKIRGRQLGAVGKYRIRRKYPLPRTIWDGEETSYCFRDKSRVLLRDWYCRNSYPSPREKRELAEKTHLTVTQVSNWFKNRRQRDRAGVPEPKDCLKDISEEEDLKLIRKTASKLSNSFHNPSDLSSYSAAAAAATFPGFYMNYNDMMIGAGTSYQSL
What are the official names of this protein?
Homeobox protein ceh-33.
What is the protein family that this protein belongs to?
Belongs to the SIX/Sine oculis homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYOE1_SHESW
Sequence: MYTQDRFMSPQYKARFKGYVQVTKPGIIFGNLISVAGGFLLAAKGDVNLALMLASLVGLSLVVASGCAVNNCIDRDIDAKMQRTCKRVTVTGEIAVGNVLAFGLALGVLGFSILALFTNALALLFAVIGYIVYVGVYSLYMKRNSVYGTLVGSFSGAVPPVVGYCSVTGQMDMGAAILLLMFSLWQMPHSYAIAIFRFNDYAAANIPVLPVAEGMTKAKLHIVLYIAVFALVSALLPLAGYTGIAFMAVTCATSLWWLAMALKGYRHGVDIQRWARQVFGFSIITIMALSITMALDSQVIKEQVIGQTNLFTLVK
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase 1, Heme B farnesyltransferase 1, Heme O synthase 1.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VPP4_MOUSE
Sequence: MASVFRSEEMCLSQVFLQVEAAYCCVAELGELGLVQFKDLNANVNSFQRKFVNEVRRCESLERILRFLEDEMQNEILIQVPEKDAETPLPREMITLETTLEKLEGELQEANQSHQALKKSFLELTELKYLLKKTQDFFETETNLGEDFFVEDTSGLLELRTIPAFMTGKLGFTAGVINRERMASFERLLWRVCRGNVYLKFSEMDTLLEDPVTKEEIKKNIFIIFYQGEQLRLKIKKICDGFRATIYPCPEHAAERREMLTSVNVRLEDLITVITQTESHRQRLLQEAAANWHSWVIKVQKMKAVYHVLNMCNIDVTQQCIIAEIWFPVADTRHIKKALEQGMELSGSSMIPIMTEVETKTDPPTFNRTNKFTAGFQNIVDAYGVGSYREINPAPYTIITFPFLFAVMFGDCGHGMVMLMAALWMVLNERHLLAQKSTNEMWNIFFNGRYLILLMGIFSIYTGLIYNDCFSKSFNIFGSSWSVQPMFRNGTWNTHIVENSPYLQLDPAIPGVYSGNPYPFGIDPIWNLASNKLTFLNSYKMKMSVILGIAHMIFGVILSLFNHIYFRRTLNIILQFIPEMIFMLSLFGYLVFMIIFKWCRYDAHTSRKAPSILIHFIGMFLFDYDDSSNAPLYGHQQEVQTFFVIIALVSVPWMLLIKPFVLRAKHQKSQLQSFTIHEDAVEGDHSGHSSKKTAGAHGMKDGHEEEFNFGDIFVHQAIHTIEYCLGCISNTASYLRLWALSLAHAELSEVLWTMVMSIGLRLQGWAGLVGVFIIFAVFAVLTVAILLVMEGLSAFLHALRLHWVEFQNKFYEGAGSKFSPFSFKHVLEGTAEE
What is the function of this protein?
Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).  Involved in normal vectorial acid transport into the urine by the kidney (By similarity).
What are the official names of this protein?
V-type proton ATPase 116 kDa subunit a 4, V-ATPase 116 kDa isoform a 4, V-type proton ATPase 116 kDa subunit a isoform 4, Vacuolar proton translocating ATPase 116 kDa subunit a isoform 4, Vacuolar proton translocating ATPase 116 kDa subunit a kidney isoform.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase 116 kDa subunit family.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Note=Localizes to the apical surface of alpha-intercalated cells in the cortical collecting ducts of the distal nephron (PubMed:11498539, PubMed:11495928). Localizes to the basolateral surface of beta-intercalated cells in the cortical collecting ducts of the distal nephron (PubMed:11498539, PubMed:11495928).
Protein: CU57_ARADI
Sequence: NPLLATSIINTGSSISARSQDGLGNYAFNYGIGNGLGATNSRAEFGDAAGNKKGSYTITDIDGRARRVDYVADAAGFRASIKTNEPGTALSAPAAAAIVSPYAPPVAPVAPAVAAPVVAAAPALAGAHLLAAPGISSYSSVIGHGAGLYAPGIAKTIFW
What is the function of this protein?
Component of the rigid cuticle of the spider.
What are the official names of this protein?
Adult-specific rigid cuticular protein 15.7, ACP 15.7.
Protein: VATD_CHLAB
Sequence: MSSQVKLTKNAYRLEKVKLSRLETYLPTLKLKKALLQVEVTNAIREASECIQAYEESRESIYAFAELYSVPLYVDAIVNSFKIERVEKEYENVTGVEVPVIKNIVLTESSYSVLDTPIWVDTLVAYSREFVVNKVRSEVAVEKQRILEDELRNVSIRVNLFEKKLIPETTRMIKKIAIFLSDRSITDVGQVKMAKKKIQQRKEESECA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit D, V-ATPase subunit D.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase D subunit family.
Protein: HH_DROGR
Sequence: MDNEAVSALWSCASATCLSLDVKRHCSDANVDSQARTQSQATPMTNETDPRKLRHIAHTPRGSCFMTLLLLLLLALNFRHAHSCGPGRGLGRRRDRNLYPLVLKQTVPNLSEYQSGASGPLEGVIDRKSPKFKDLVPLYNSDILFRDEEGTGADRMMTKRCKEKLVMLATSVMNEWPGVKLLVTESWDEDHHHGEQSLHYEGRAVTIATSDRDQSKYGMLARLAVEAGFDWVSYVSRRHIYCSVKSDSSSSISHVHGCFTPESTAQLESGAKKPLGELAIGDRVLSMDAKGQAVYSEVILFMDRNLEQMETFVQLHTDGGAVLTVTPAHLITVWQPERQTLDFVFADHVEELNYVLVVDDATGGELRPQRVLRVSSVRRRGVVAPLTREGTIVVNSVAASCYAVISSQSLAHWGLAPMRLWSTLQSWLPAKDKLRSSKVQEKSTPKVNSTAQLQNGLHWYANALYKVKDYVLPQSWRHD
What is the function of this protein?
The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.  Establishes the anterior-posterior axis of the embryonic segments and patterns the larval imaginal disks.  Binds to the patched (ptc) receptor, which functions in association with smoothened (smo), to activate the transcription of target genes wingless (wg), decapentaplegic (dpp) and ptc.  In the absence of hh, ptc represses the constitutive signaling activity of smo through fused (fu).  Essential component of a signaling pathway which regulates the Duox-dependent gut immune response to bacterial uracil; required to activate Cad99C-dependent endosome formation, norpA-dependent Ca2+ mobilization and p38 MAPK, which are essential steps in the Duox-dependent production of reactive oxygen species (ROS) in response to intestinal bacterial infection.  During photoreceptor differentiation, it up-regulates transcription of Ubr3, which in turn promotes the hh-signaling pathway by mediating the ubiquitination and degradation of cos.
What are the official names of this protein?
Protein hedgehog.
What is the protein family that this protein belongs to?
Belongs to the hedgehog family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Nuclear up to embryonic stage 10 and then at stage 11 shifts to the cytoplasm. Also secreted in either cleaved or uncleaved form to mediate signaling to other cells. SUBCELLULAR LOCATION: [Protein hedgehog N-product]: Cell membrane; Lipid-anchor. Note=The N-terminal peptide remains associated with the cell surface. Heparan sulfate proteoglycans of the extracellular matrix play an essential role in diffusion. Lipophorin is required for diffusion, probably by acting as vehicle for its movement, explaining how it can spread over long distances despite its lipidation.
Protein: DBP5_ASPOR
Sequence: MSAEQPAETASAGNPLADRITTADGSKPEGTTETTDNEQADGAAAQLGGSELNEPDYTVEVKLSDLQADPNNPLYSVKSFEDLGLDPRILQGLSAMNFRKPSKIQERALPLLLNNPPKNLVGQSQSGTGKTAAFVLNALSRLDLSTEQAQKTPQALILAPTRELARQIVGVIQCMGQFLDGLNVSTAVPADTNSRHSKIESSVVVGTPGTVMDMIRKRVMVANKLKVLVLDEADNMLDQQGLGDQCIRVKALLPKDIQVVLFSATFPTHVHQYASKFAPQANELTLQHEELTVEGIKQLYLDCSDEEDKYKTLVQLYGLLTVASSIIFVKTRASAAEIEKRMVAEGHTVASLTGGIEGSQRDAVIDQFRAGQAKVLITTNVLARGIDVSTVSMVINYDIPELHQPGAPERQADFQTYLHRIGRTGRFGRVGVSISFVSNREEWNMLNQIQQYFNCTIQRVDTKDWDEVEDIIKKTIKNTRAQAQFGR
What is the function of this protein?
ATP-dependent RNA helicase associated with the nuclear pore complex and essential for mRNA export from the nucleus.  May participate in a terminal step of mRNA export through the removal of proteins that accompany mRNA through the nucleopore complex.  May also be involved in early transcription (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase dbp5.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX19/DBP5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Nuclear pore complex cytoplasmic fibrils.
Protein: TATB_GRABC
Sequence: MFDFAWSEIAVIGVVALVVIGPKDIPGAVRGVARMVRKARSMAAEFQGQMDQMMKEADLGDVRETFNDLRGVNLRQQLSRTLDPDGSMRSTFDNNPMAPSPAPMIMGGDEAHMVEERPFHSLSVMDESHMASEWTREKTVSSETARRAATAPAFIPPGEAFRSARRAPAFIPPADQG
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: EPHA6_RAT
Sequence: MGGCEVREFLLQFGFFLPLLTAWTGDCSHVSNQVVLLDTSTVMGELGWKTYPLNGWDAITEMDEHNRPIHTYQVCNVMEPNQNNWLRTNWISRDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFTLYYIESDESHGTKFKPSQYIKIDTIAADESFTQMDLGDRILKLNTEVREVGPIERKGFYLAFQDIGACIALVSVRVFYKKCPFTVRNLAMFPDTIPRVDSSSLVEVRGSCVKSSEERDTPKLYCGADGDWLVPLGRCICTTGYEEIEGSCHACRPGFYKAFAGNTKCSKCPPHSSTFVEATSVCHCEKGYFRAEKDPPSMACTRPPSAPRNVAFNINETALILEWSPPSDTGGRKDLTYSVICKKCGVDASQCEDCGAGLRFIPRPTGLINNSVVVLDFVSHVNYTFEIEAMNGVSELSISPKPFTAITVTTDQDAPSLIGMMRKDWASQNSLALSWQAPAFSNGAILDYEIKYYEKEHEQLTYSSTRSKAPSVIITGLKPATTYIFHIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILVIATAAVGGFTLLVILTLFFLITGRCQWYIKAKMKSEEKRRTHLQNSHLRFPGIKTYIDPDTYEDPSLAVHEFEKEIDPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNGIQAPHPVTAGGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDVWSYGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPPSLHQLMLHCWQKERNHRPKFTDIVSFLDKLIRNPSALHTLVEDILVMPESPGDVPEYPLFVTVGDWLDSIKMGQYKSNFMAAGFTTFDLISRMSIEDIRRIGVILIGHQRRIVSSIQTLRLHMMHIQEKGFHV
What is the function of this protein?
Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.  The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling (By similarity).
What are the official names of this protein?
Ephrin type-A receptor 6, EPH homology kinase 2, EHK-2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RS21_STAEQ
Sequence: MSKTVVRKNESLEDALRRFKRSVSKSGTIQEVRKREFYEKPSVKRKKKSEAARKRKFK
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: SLA_DABPA
Sequence: DQDCLPGWSFYEGNCYKAFDEPKSWVDAEKFCQKQSNGKHLASIEGLGKANFVAKLVSEDQSETLREPQIHVWIGLRDQSERQQCSSHWTDGSAVSYECGLAYPFIC
What is the function of this protein?
Inhibits integrin alpha-2/beta-1- (ITGA2/ITGB1) dependent melanoma metastasis.
What are the official names of this protein?
Snaclec VP12 subunit A.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: CLK1_HUMAN
Sequence: MRHSKRTYCPDWDDKDWDYGKWRSSSSHKRRKRSHSSAQENKRCKYNHSKMCDSHYLESRSINEKDYHSRRYIDEYRNDYTQGCEPGHRQRDHESRYQNHSSKSSGRSGRSSYKSKHRIHHSTSHRRSHGKSHRRKRTRSVEDDEEGHLICQSGDVLSARYEIVDTLGEGAFGKVVECIDHKAGGRHVAVKIVKNVDRYCEAARSEIQVLEHLNTTDPNSTFRCVQMLEWFEHHGHICIVFELLGLSTYDFIKENGFLPFRLDHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVQSDYTEAYNPKIKRDERTLINPDIKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQPCDVWSIGCILIEYYLGFTVFPTHDSKEHLAMMERILGPLPKHMIQKTRKRKYFHHDRLDWDEHSSAGRYVSRRCKPLKEFMLSQDVEHERLFDLIQKMLEYDPAKRITLREALKHPFFDLLKKSI
What is the function of this protein?
Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates.  Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing.  Phosphorylates: SRSF1, SRSF3 and PTPN1.  Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells and adenovirus E1A pre-mRNA.
What are the official names of this protein?
Dual specificity protein kinase CLK1, CDC-like kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. Lammer subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRMB_NOCFA
Sequence: MDGVNDAANHTVESVPGRPSTASAPLEAGRRSPTGSRLYPRVTSFRSRRGALTPNQQGAWDRMWPRIGREVGDEPLDADAWFGRQAPLVIEIGCGTGTATAAMAAAEPHVNLIGIEVYQPGLAQLVQRIERDGIDNIRLLRGDAVDVLEHMIAAESLTGVRVFFPDPWPKARHHKRRLLQPATVALIAGRLRPGGVLHVATDHAGYAEHIAAVGAAEPLLVGLNEATGGDDERARTLAPIGLDRPVTKFEDKAHRAGSAITEFVWGKIE
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: TATC_FRACC
Sequence: MPGLPTPRRLVASVNYRRTRTVEDSRMPLTEHLRELRNRVAIALLAFAIAGVVCFIFEPRIFDWLKAPYCDLPASKRFSPDGLAANDCTLYFFGILDAFTIRLKISMIAAVVVSSPVWLYQLWSFITPGLHRHERRWSLTFVGVSLVLFATGAVFAYLTLSTGLGLLLGFGGNGLVSVLDGNRYLSYVQAMLLIFGLSFEVPLLVMMLNLAGIVSTAKLRSWRRPEIFLVFVFAAVVTPSQDPFTMLALGLPMVLLYEVALIIGWLNDRRVARRGDTSPYADLDDDETSPLDFDDAPPRPAASAGPAATATSPGTANPPGTANPPGTANPVGTANPVGTGSSTPVGAGTAPVSPSTDVTHGDIT
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
What are the official names of this protein?
Sec-independent protein translocase protein TatC.
What is the protein family that this protein belongs to?
Belongs to the TatC family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ERP6_YEAST
Sequence: MLSHYIFLAFVLLPFRVSAFYFYGYGGDRKCFLKELSKDTLLKGSYNLEVYDDKLADYALPSYNDYGIVIDVEEVFDNNHRVVHQQGSPSGDFSFLALESGEYKICLQSRVNNWVGKTKTKLEIEFEVGFEAMLDMQRKETLESLHGKVSILNSKIVDIRREQQLMREREESFRDISESVNSRAMWWTVTQVTLLIIICVWQMKSLRSFFVKQKVL
What is the function of this protein?
Involved in vesicular protein trafficking.
What are the official names of this protein?
Protein ERP6.
What is the protein family that this protein belongs to?
Belongs to the EMP24/GP25L family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.