PharMolix/UniProtQA huggingface dataset:
Protein: TSAD_DESVV
Sequence: MLCIGIETSCDETGLALVRDGRLVHAVMSSQADIHALFGGVVPEIASREHYRLIGPLYDLLLREAGVGPTELDAVAVARGPGLLGSLLVGMAFAKGLALGFDIPLVGVNHLHAHLLAAGLERELVFPALGLLVSGGHTHIYRIESPVSFRLLGRTLDDAAGEAYDKVAKMLRLPYPGGRILDQQGRRGIADPRLFPRPYTDNDNLDFSFSGLKTAVQTHLSRHPELVPSPDAAQAVAGGHDAPEGLRNMCASFNEAVAETLCIKLGRALDGDDGVGVRALIVAGGVAANSYVREHTARLAVSRGLELIVPSPPLCTDNGSMIAYAGWLLRQGGLSHSLDLEAVPRGRAIPDDYRQGPAGCS
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BLAC_STRBA
Sequence: MHHPRVRTAVAGLVAVLSLVPLAACGQSDSTAPPSSAKPATSASASLPRPKPYTGDFKKLEREFDARLGVYAIDTGTGREVTHNDRARFAYHSTFKALQAAVVLSTYSLDGLDKRVTYTREDLVAHSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDPRAAGPKGLDASLEKLGDDITRMDREEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALRAPERAQLTTWLRTNTTGDAVIRAGVPENWVVGDKTGTGSYYGARNDIAVVWPPDSAPIVIAILSHRGTKDAEPDDELIAEAASVVVDSLSS
What are the official names of this protein?
Beta-lactamase, Penicillinase.
What is the protein family that this protein belongs to?
Belongs to the class-A beta-lactamase family.
Protein: HUNB_APIME
Sequence: KHHLEYHLRNHFGSKPFKCEKCSYSCVNKSMLNSHLKSHSNVYQYRCANCTYATKYCHSLKLHLRKYSH
What is the function of this protein?
Gap class segmentation protein that controls development of head structures.
What are the official names of this protein?
Protein hunchback.
What is the protein family that this protein belongs to?
Belongs to the hunchback C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYGB_LISMH
Sequence: MSKDFLLEIGLEEMPAQYVTSSVLQLEKRVTDWLTENKIEFGEIKTYSTPRRLTVLVEGMAEEQANRVEEAKGPAKKIALDDEGNWSKAALGFAKSQKVDPADLTFRDIKGVEYIYIKKEVIGEKTSTLLPNLEKVVTSMTFPVSMHWGSNDLRYIRPIKWLIAMFGEEIIPFEITGVTTSNTSRGHRFLGKSATIKQPSDYPNALLEQFVVVNAEERKQAIVEQLRELESMENWQIKEDDDLLEEVTNLVEYPTVLSGNFEKEYLELPEEVLITTMKEHQRYFPVFSQAGELLPHFVTVRNGNHENLDTVARGNEKVLRARLSDADFFYQEDLKMTIDEAVAKLQNIVFHEKLGTLTEKMKRVQKVALMLADYLDWQEEDKQDIIRLTNIYKFDLVTNIVGEFPELQGLMGEKYALLQGEKPAIATAIREHYLPNSAEGELPQTDLGSLIAIADKLETLIGFFCVNIVPTGSADPFGLRRSAFGAMRIIQANGWDIPMLEVISRIVDMERAEGSAELPGADVKKEVQTFLKNRLRVILQGHHIRHDIIDAVIGGDPNVIPQLIDRAQILNEHAEAEWFRPTIEALSRVVKIAKKYEDGVEVDPALFENEYEQALFDKLEKLKFDYAGLTIIERLKAFADLRTTIDAYFDNTLVMSDNDELKNNRLALLFELASFIKEFAQMDEINVK
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNMA2_HUMAN
Sequence: MALALLEDWCRIMSVDEQKSLMVTGIPADFEEAEIQEVLQETLKSLGRYRLLGKIFRKQENANAVLLELLEDTDVSAIPSEVQGKGGVWKVIFKTPNQDTEFLERLNLFLEKEGQTVSGMFRALGQEGVSPATVPCISPELLAHLLGQAMAHAPQPLLPMRYRKLRVFSGSAVPAPEEESFEVWLEQATEIVKEWPVTEAEKKRWLAESLRGPALDLMHIVQADNPSISVEECLEAFKQVFGSLESRRTAQVRYLKTYQEEGEKVSAYVLRLETLLRRAVEKRAIPRRIADQVRLEQVMAGATLNQMLWCRLRELKDQGPPPSFLELMKVIREEEEEEASFENESIEEPEERDGYGRWNHEGDD
What are the official names of this protein?
Paraneoplastic antigen Ma2, 40 kDa neuronal protein, Onconeuronal antigen Ma2, Paraneoplastic neuronal antigen MM2.
What is the protein family that this protein belongs to?
Belongs to the PNMA family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ARNF_YERPN
Sequence: MKGYLWGGASVVLVTVAQLVLKWGMMNIPLLSLADINVQFLTMYFVQLASVMCGLMGYALSMLCWFFALRYLPLNRAYPLLSLSYALVYLGAVLLPWFNEPATLLKTLGAGFILLGIWLINIKPIKAS
What is the function of this protein?
Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
What are the official names of this protein?
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF, L-Ara4N-phosphoundecaprenol flippase subunit ArnF, Undecaprenyl phosphate-aminoarabinose flippase subunit ArnF.
What is the protein family that this protein belongs to?
Belongs to the ArnF family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ASSY_BIFAA
Sequence: MLERETMSDQNRLVLAYSGGLDTSVAISYLKERTGKDVVAVSLDVGQGGESLETIKQRALACGAVEAYVVDARDEFANEYCMKALKANAMYEGVYPLVSAISRPLISKHLVRAAHQFGADTISHGCTGKGNDQVRFEVSIASIDPTLKAISPIRDLSLTRDVEIAFAKEHKLPIVQTEKSPFSIDQNVWGRAIETGFLEDPWNGPTKDCYSYTDDPAFPPVEDEVVIEFKQGVPVKIDGHDVTPLQAIEEMNRRAGAQGIGRIDLIEDRLVGIKSRELYEAPGAVALITAHQELENCCLEREQHRIKRDIDKRWAELVYDAQWFSPATQSLNAFIEDTQKYVSGEIRMVLHGGRAVVTGRRSDSSLYDYNLATYDSGDSFDQKSSNGFIDIYGLPSRVAAARDVKFGNGIEVPENSVE
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_SORIS
Sequence: MTNLRKTHPLMKIVNSSFIDLPAPSNISSWWNFGSLLGVCLIIQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYMYLETWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGSDLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAGVHLLFLHETGSNNPSGLCSDADKIPFHPYYTIKDILGVLLLILVLTSLVLFSPDLLGDPDNYTLANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILVLALVPFLHTSKQRSMMFRPFSQCFFWILVADLLTLTWIGGQPVEHPFIIIGQLASILYFLLILVIMPITSLFENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MIAA_ALKCK
Sequence: MTQEPLIAIVGPTAVGKTALGIELAKTFGAEIISGDSMQVYRTMDIGTAKATVEEMAGIPHHLIDILEPGDTWTVSMFQEKALLAIASIRSRGKWPLLVGGTGLYVQALTHELSFGDAPSDSSFREEMELYASRFGNAALHGKLAKADPNAAEAIHANNVRRVIRALEVIHLTGKPFSEQENGLARPRFDNVLIGLEMERQALYERINRRVDAMMEAGLLEEVHRLYQRGIQGQAIQAIGYKELYAYFDGKCTYDEAIEALKTNSRRYAKRQLTWFKNRSDAVWFHLEEPEAKAKIFDYVHAFLAGKGFA
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: SUN5_MOUSE
Sequence: MPRTRNIGALCTLPEDTTHSGRPRRGVQRSYISRMAEPAPANMNDPLLLPLRMNTPGLSLVQILLGYMSWLTYLACFLRTQTQQVFLNTCRCKLFCQKVMEKMGLLVLCVFGFWMFSMHLPSKVEVWQDDSINGPLQSLRMYQEKVRHHTGEIQDLRGSMNQLIAKLQKMEAISDEQKMAQKIMKMIQGDYIEKPDFALKSIGASIDFEHTSATYNHDKARSYWNWIRLWNYAQPPDVILEPNVTPGNCWAFASDRGQVTIRLAQKVYLSNITLQHIPKTISLSGSPDTAPKDIVIYGLESLPREEVFLGAFQFQPENVIQMFQLQNLPPRSFAAVKVKISSNWGNPRFTCMYRVRVHGSVTPPKDSHLEPLS
What is the function of this protein?
Plays an essential role in anchoring sperm head to the tail.  Is responsible for the attachment of the coupling apparatus to the sperm nuclear envelope.
What are the official names of this protein?
SUN domain-containing protein 5, Sperm-associated antigen 4-like protein.
What are the subcellular locations of this protein?
Nucleus inner membrane; Single-pass membrane protein. Golgi apparatus. Note=During spermiogenesis, traffics through the Golgi apparatus before reaching the round spermatid inner membrane of the nuclear envelope and later migrates to the coupling apparatus of the sperm during sperm head elongation and differentiation. In mature spermatozoa, is localized to the coupling apparatus of the sperm head and tail in the implementation fossa.
Protein: EI3F2_DROYA
Sequence: MSRNFSMQAKVFIKPLVLFQIIDAYERRPKGDNQVMGTLLGRNKEGHFEITNCFPVPHKEHPEINRIDLDISYASEFLELNMLTYSNERVLGWFSTGKSVSRSASLLHDYYARECGEIQPVHLVMDATLKSQRLSTRLYCAVEIGVPGGTKGLMFSLVPLEISNGNSDLVALRSLEKQSLQQGTKQMERFLPELVQVVDATRDIQQRLDLVLRYINDVLARKRKPDNVIGRALYAALTAVPLLDSEKFRLMFNTNLRDMLMAITLSTMIKTQLEISEKLSCMQDQ
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit F-2, eIF3f-2, Eukaryotic translation initiation factor 3 subunit 5-2.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit F family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNA_CALS8
Sequence: MKHFEFENDKLIVLDQRKLPFEKEYFVCSTYQDVYIAIKDMIIRGAPLIGIVAAYGVVLGFKEIIEKNMDSAKIYEILNYLANSRPTAVNLFWALERMKKVFEEARNLSKSQIYSLLMQEAKKIEDEDKSINKKIGEHGNTLIKEGANILTHCNAGALATGGYGTALGVIREAFFAGKNIHVYVDETRPYLQGARLTAFELSEDGIPNTVICDNMAGYLMKLGKIDCVIVGADRIALNGDTANKIGTYSLSVLAKHHGIPFYISAPISTIDFNIKSGSEIPIEERSEDEIRFFNGKKIVPDESKVFNPAFDVTPAENITAIITEKGVVFPPFEENISKLKEK
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: RS11_ACTP2
Sequence: MAKTPVRARKRVKKQIADGVAHIHASFNNTIVTITDRQGNALAWATAGGSGFRGSRKSTPFAAQVAAERCAEAVKEFGLKNLEVMVKGPGPGRESTIRALNAAGFRITNITDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: YXNB_BACSU
Sequence: MEKQKVLALPDDVHELSTHRSKSIVNYIITLLAFAKKQGLTHQDIVSWIHEQYEERGYYDEWRHINSQQPVGSFVELFIKGRRLLYDKIELFETEDKYVVNTHTWYEKEPSEAFFYFEIDPEEFSAYASILAIENAKRLGIKIDIVKETDVETAYIYKHQ
What are the official names of this protein?
Uncharacterized protein YxnB.
Protein: PAND_HYPNA
Sequence: MILSMLKAKLHGATVTQCDLHYEGSVSIDQDLLDASGILPHEKVDIWNVTNGARIQTYALEAPRGSRTIGVNGAAARHFAVGDTVIIAAFCGVEAEKARQHAPTVVLLGEGNEIKRAS
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAE_HELHP
Sequence: MDKQLRYAIALTGSIGSGKSTFVSLLSLYGYQSICADSIAHKVLEEHSAEVIAYFGNEILQSDNTINRKVLGNIIFASSSKREELQAILHPHIQKAILTQAQQLEEKKVWYFIDIPLFFEVGGKEAYPVARSLVIYTPKAKAIERIMKRNNFTFEEAKARIDAQMPIENKCRLADDIINNEGDLRTLQHNAETYIQSLPCVDCVQSS
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_POLSJ
Sequence: MIEKSIKAEIVKANARAANDTGSPEVQVALLTGRINELTPHFKANAKDHHGRRGLLRMVSRRRKLLDYLKSKDADRYTALIAKLGLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: NPB_RAT
Sequence: MVRCRTLVAAALALLLTPALAWYKPAAGSHHYSVGRAAGLLSSFHRFPSTRRSESPALRVGTVPLRNLEMRPSVRSLALCVKDVTPNLQSCQRQLNSRGTFQCKADVFLSLHKAECQSA
What is the function of this protein?
May be involved in the regulation of feeding, neuroendocrine system, memory and learning.  May be involved in the afferent pain pathway (By similarity).
What are the official names of this protein?
Neuropeptide B, Preproprotein L7, rPPL7.
What is the protein family that this protein belongs to?
Belongs to the neuropeptide B/W family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS17_THEAN
Sequence: MGRVRTKTVKRAARQIVEKYYGKLGLDFQYNKKVAEEVALIPSKRMRNKVAGFITHLMRRIQKGPVRGISLKLQEEERERRMDYIPEKSELEVPVIQVDQDTADMLNFLKISLPNLKVMSFNAHEHREDTK
What are the official names of this protein?
40S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS17 family.
Protein: G6PI_TOLAT
Sequence: MKNINPTQTKAWKALETHFAANKDRQLSELFAADPARFDKFSTTYKDNILVDYSKNLITDETLDLLIDLAHEVDLRSAIDAMFNGEKINHTEGRAVLHTALRNRSNRPVMVDGKDVMPEVNAVLAKIKAFCDSVISGEWKGYTGKAIQHVVNIGIGGSDLGPVMITEALRPFKNHLQMHFVSNVDGTHIAETLKNVDPETTLFLVASKTFTTQETMTNALSARDWFVNIAGDQAHVAKHFAALSTNTKAVAEFGIDTANMFEFWDWVGGRYSSWSAIGMPIALSLGFENFEALLEGAFEMDTHFATTSYEQNIPVLLALIGLWYNNFYEAESEAILPYDQYMHRFAAYFQQGNMESNGKYVDRNGNKVDYQTGPIIWGEPGTNGQHAFYQLMHQGTKLIPCDFLAPAITHNPIGDHHPKLLANFFAQTEALAFGKSKEAVEAEFLAAGKTLEQVKDLVPFKVFEGNRPTNSILFKQMTPQTLGALIAMYEHKIFVQGIIWNIFSFDQWGVELGKQLANKILPELNSDAAVTSHDSSTNGLINTWKAWKA
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCD_NAUPA
Sequence: MGVKSDIWIRNMAKNFNMISPFEEKQVRKGIISYGVSSYGYDIRVSDEFMVFTNINSTVVDPKNFDERNVVNIKGDCIIPPNSFALCRSVEYFKMPRDVLAICVGKSTYARCGIIVNVTPIEPEWEGHITIEISNTTPLPAKIYANEGIAQLIFLGADDNICETSYADKSGKYHGQKGITLPKVDK
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: OFUT4_ARATH
Sequence: MISQVERDLSIQNRLPGSDHTTPSPPTSPHLCRSRSKSSSVSGQQQSRNVAHRLSWIILSVLLRRQGILLFAPIIYISCMLFHLHAASFDASPIIHRRPAPGSVYRSPQVYARLRGEIEADNTTADAISTIWKRSYKGVEWKPCVNMSTGVLPVSNGFIFIEANGGLNQQRTSICNAVAVAGYLNATLVIPNFHYHSIWKDPSKFGDIYDEEYFIDTLANDVRVVDTVPEYLMERFDYNLTNVYNFRVKAWAPTSYYRDSVLPKLLEEKVIRISPFANRLSFDAPRAVQRFRCLANNVALRFSKPILTQGETLVNKMKGLSANNAGKYVSVHLRFEEDMVAFSCCVFDGGDQEKQDMIAARERGWKGKFTKPGRVIRPGANRLNGKCPLTPLEVGLMLRGMGFNKSTYIFLAAGPIYSANRTMAPLLEMFPNLQTKEMLASEEDLAPFKNFSSRMAAIDYTVCLHSEVFVTTQGGNFPHFLMGHRRYLFGGHSKTIQPDKRKLAVLFDNPKLGWKSFKRQMLSMRSHSDSKGFELKRSSDSIYIFPCPDCMCRKNKTTASAT
What are the official names of this protein?
O-fucosyltransferase 4, O-FucT-4, O-fucosyltransferase family protein.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase GT106 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: DEFB1_TRAOB
Sequence: MRTSYLLLFTLCLLMSEMASGDNFLTGLGHRSDHYNCVRSGGQCLYSACPIYTKIQGTCYHGKAKCCK
What is the function of this protein?
Has bactericidal activity.  May act as a ligand for C-C chemokine receptor CCR6.  Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner.  Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.
What are the official names of this protein?
Beta-defensin 1, BD-1, Defensin, beta 1.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted. Membrane. Note=Associates with tumor cell membrane-derived microvesicles.
Protein: SCXE_TITPA
Sequence: KDGYLVGNDGCKYSCNTYPK
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
What are the official names of this protein?
Toxin TpF21-Cocle.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GATE_METS3
Sequence: MDWEKLGLKMGLEIHQQLNTKHKLFCPCKTELVDEDYNEIVERNLRPTQSELGEIDRAALQESLRGLNFKYESYDHHTCLVESDDEPPHSLNKEALEICITIAALMNMHIVDEFHTMRKQVIDGSNTGGFQRTGLAATDGYLDTPYGRVAIESLGLEEDAARRIETTEDYTEFRLDRLGIPLAEITTDPSMHHPDQVREVAYMIGQVLRSTNVKRGLGTIRQDLNISIEKGARVEIKGVQNLDLMSEIVENEVQRQLALIEIKEELNKRNAEVLEEIHDLDSLFENTKSKILSSAESIKAVVLKGFNGLIGKEVQPGRRFGTEIASYAKKRGVSGIFHSDELPAYGITQDEVNSVKDYLNVGSQDAFIIVAHDENVAISALEEVKRRANLGFEGVVEETRKSLDDGNTEYMRPLPTANRMYLETDIPLFKITDELVEPIKNNLPELPDVKKERIIKEYNLSEDLASQLVKRLEADVFEEILTDVEVDPTPVASLLAYDLREIKREGLDIDILTTRHLKDIFQLLADSKIAKDSVTKLTTCVIQSPDEEIEITAKNNNLTLLSHEEVTQIIEDIVNKNEAMVKERQMGAMGPLMGMSMKELKGKADGSIVNRIVKESIQKML
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).  The GatDE system is specific for glutamate and does not act on aspartate.
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit E, Glu-ADT subunit E.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatE subfamily.
Protein: APOA4_MOUSE
Sequence: MFLKAAVLTLALVAITGTRAEVTSDQVANVVWDYFTQLSNNAKEAVEQFQKTDVTQQLSTLFQDKLGDASTYADGVHNKLVPFVVQLSGHLAQETERVKEEIKKELEDLRDRMMPHANKVTQTFGENMQKLQEHLKPYAVDLQDQINTQTQEMKLQLTPYIQRMQTTIKENVDNLHTSMMPLATNLKDKFNRNMEELKGHLTPRANELKATIDQNLEDLRRSLAPLTVGVQEKLNHQMEGLAFQMKKNAEELQTKVSAKIDQLQKNLAPLVEDVQSKVKGNTEGLQKSLEDLNRQLEQQVEEFRRTVEPMGEMFNKALVQQLEQFRQQLGPNSGEVESHLSFLEKSLREKVNSFMSTLEKKGSPDQPQALPLPEQAQEQAQEQAQEQVQPKPLES
What is the function of this protein?
May have a role in chylomicrons and VLDL secretion and catabolism.  Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT.  Apoa-IV is a major component of HDL and chylomicrons.
What are the official names of this protein?
Apolipoprotein A-IV, Apo-AIV, ApoA-IV, Apolipoprotein A4.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted.
Protein: COW_CONMO
Sequence: QGDRDQPADRNAVPRDVNPGRARRKLMKVLRESECPWKPWCG
What is the function of this protein?
Its target is unknown, but this toxin may modulate voltage-activated calcium channels (Cav) or calcium-dependent potassium channels (KCa).
What are the official names of this protein?
Contryphan-Mo.
What is the protein family that this protein belongs to?
Belongs to the O2 superfamily. Contryphan family.
What are the subcellular locations of this protein?
Secreted.
Protein: MSCL_STRM5
Sequence: MGMLTEFKEFAMRGNVIDLAVGVVIGAAFGKIVTALVEKIIMPPLGMLIGKVDFSQLAWTLSPASIGADGKEIPAVVIGYGDFINTLIQFVIVAFAIFLVIKVINRLSRKQDAAPAAPAEEVVLLREIRDSLKK
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1259_THEVO
Sequence: MMRRYRRKNSSIPIIVEGRNDLASLRKLSFYGEIIVFNRGISITSFSDEISNKYREVIILTDFDNKGSFLKDRFYGYLTGMGVYVDLYLWNFIRKHVPIRTVEELPAEFEREVEKEIQM
What are the official names of this protein?
UPF0292 protein TV1259.
What is the protein family that this protein belongs to?
Belongs to the UPF0292 family.
Protein: CUE_DROMO
Sequence: MKLCSLQQLVLAVLFIVSNFYLPLAVASPIGWDFAVTLRDKLLFLDNKFKTVSSAAHEFEGISALAFDEAEEVIYFNDQQHQNGSIFSLRRDAAVASHIVEQAVQRIGNGSVSGLAFDPLNRNLFWADMRQSRIYFASVDTLHTEPPKVLVDLSAEGGRPDGVAVDICRRQLYWTNSKINHASVERIGLNGTGRQVIIKENIDMPRGIVIDQQSDRIYWLDDKVGIFFAIESARLDGSDRQLVLEDKHQSPIQLAITDETIYWTDKADKAVWSYPKPANKKLATNATEPVVEPIKLASWKEDVYGIVARTGFYQHLQKDAHCASVVKKVKQRLDNRLNNRTQSRTAVDDRIEELEREHCLNGATYMTKGNFCICQVGFKGARCEISECHNYCVHGTCEISSMGYPKCYCQTDFYGERCEYYKCNNHCLNGGHCTVDRDSGEMSCDCRDNFTGTRCEHNETAHCGSYCQHLKEHPDAFVPAPCMDICEELRLTNATIVREYQSSAFCSDMPSYRQGSLIIVLVVGVVSSLALVAVIVHGFRLIHKPKRPRIKKTFVVRKQARLNSTSDTPLTNRPLATEQCEITIENCCNMNICETPCFDPKLVEQQFSGRDKKSPCVKEDKKILIHNMEDDLLN
What is the function of this protein?
Has a role in spermatogenesis and oogenesis.
What are the official names of this protein?
Protein cueball.
What is the protein family that this protein belongs to?
Belongs to the cueball family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: OBG_SYNFM
Sequence: MKFVDEVKVHVLSGNGGNGCVSFRREKYVPRGGPDGGDGGEGGSVIFVASEGKNTLLDFRYRHLFKAESGKHGQGRNRHGKGGRDLVLEVPAGTVIKDAETGEPLVDLSHPGDRWVAARGGRGGRGNARFVSSTRQAPRIAEDGREGEDRELVLELKLMADVGLVGLPNAGKSTLISVVSAARPRIADYPFTTLIPCLGVVRHGEAPPFVMADIPGLIEGAHDGAGLGIRFLRHIERTRILAHLVDISQLSPEEPLRPYRLIESELASYSARLGEKKRVIVLNKVDLVPERDRLEALVSRYEQLGHPVFPVSARTKEGLGELLSALVRILSESGVSLPVEDVEEHVGK
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUR31_SCHPO
Sequence: MVQPELTQSVGYGIVVGLGLGFAALMIFVSWSLKKFNNENQTSEHFNTASHSVRTGLVASAVVSSWTWASTLLTSAQKTYQYGVSGAFWYASGACVQILLFTVLAIELKRKAPNAHTFLEVVRARCGPIAHGVFLVFAYITNILVMAMLLCGGSATISSVTGMNTVAVCFLLPVGVIIYTMFGGIKATFLTDYIHTVIILVILIMFSLATYSADKKIGSPGKLYDMLKEAGDAHPVAGNAQGSYLTMRSQEGAIFFIINLAGNFGTVFVDNGYWQKAIAANPASALPGYILGGLAWFAIPWLAATTMGLVALGLENKPYFPTYPNRMSDLEVSEGLVLPYAAIALMGRAGANATLLLVFMAVTSAASAELIAVSSIFTYDIYKQYVRPRATGKELLYTGHASLIVFGFAMSGFATGLYYGQVSMGYLYLLMGVLVCPAVVPATCVMLFSRVSTIAVTVSPVLGIISSIITWLVVARAEGGKTLTIETTGANNPMLAGNVVGLLSPALYILILSIIFPEKYDFNRLLATFAMHFSSEEDEIQQTKKLNRASVISKVAALIITAAFIILWPWPMYGTGYIFSKRFFTGWVVVGLIWIFFTVFAVGIFPLWEGRNDIYQVVSNMAASIFGRKVNDIVEDEGVVVETISIGSGSKEKVNFEKKDIESV
What is the function of this protein?
Involved in active transport of urea.
What are the official names of this protein?
Probable urea active transporter 1.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.