PharMolix/UniProtQA huggingface dataset:
Protein: FITM1_DANRE
Sequence: MFLNSILVVITDLAAGLLGNTSFRRHFHLLLSALLLFGPLLSLWVSHYSVFAKRTHFLYRVFLRSGWGWTCIFVGSFVFVLSFSVRRSLTLSLRHLSRLAVAGGLWLGFRKLLCLLENATGSCYEPLSAALEMTSGTNGEGQPLLLLREAETKETCVRSGMLWRGYEVSEDALLLCLCCLLLAEETAVFGPYLNLGGPSEAPLRILFLFCVLLLSLWVFLLLCLLAYFPEFPTQLLGGALGCLSWRALYQGWYRLRPSWYCPGRPGVGLLSTQSKQDELLETQTNAKEID
What is the function of this protein?
May play an important role in the formation of lipid droplets (LDs) which are storage organelles at the center of lipid and energy homeostasis (By similarity).  May directly bind to diacylglycerol (DAGs) and triacylglycerol (By similarity).
What are the official names of this protein?
Fat storage-inducing transmembrane protein 1, FITM1-like protein, Fat-inducing protein 1.
What is the protein family that this protein belongs to?
Belongs to the FIT family. FIT1 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SUCC_NEIG2
Sequence: MNLHEYQAKELLASYGLPVQGGILAHNGEEAAAAYDKLGGKFAVVKAQVHAGGRGKAGGVKVVKSREKAKEVAESLIGTNLVTYQTDANGQPVNSVLVCEDMYPVQTELYLGAVVDRSTRRVTFMASTEGGVEIEKVAAETPEKIFKVTVDPLVGLQPCQAREVAFQLGLKDKQINEFAKLMTGAYKAFVENDFALFEVNPLAVRENGALACVDGKIGIDSNALYRLPKIAELRDKSQENERELKASEFDLNYVALEGNIGCMVNGAGLAMATMDIIKLKGGQPANFLDVGGGATKDRVVEAFKLILEDKSVKGVLINIFGGIVRCDMIAEAIVAAVKEINVNVPVVVRLEGNNAELGAKILNESGLKLTSADGLNDAAEKIVAAVNA
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: RS2_PSEPF
Sequence: MSQVNMRDMLKAGVHFGHQTRYWNPKMGKYIFGARNKIHIINLEKTLPMFNEALTFVERLAQGKNKILFVGTKRSAGKIVAEEAARCGSPYVDHRWLGGMLTNFKTIRASIKRLRDLEVQAEDGTFAKLTKKEALMRTRDLEKLDRSLGGIKDMGGLPDALFVIDVDHERIAITEANKLGIPVIGVVDTNSSPEGVDYIIPGNDDAIRAIQLYMGSMADAVIRGRNNVAGGTVEFAAEETQAAAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: MURC_SHESA
Sequence: MTKTERYLQLRSMIPEMRRIKRIHFVGIGGAGMGGIAEVLVNEGYVVSGSDIAQNAVTDRLCLLGAKIHIGHGADNVQQADVVVVSTAINPENPEIIAAKELRIPIVRRAEMLAELMRYRHGVAIAGTHGKTTTTSLIASLYGQAGRDPTFVIGGLLNSAGTNARLGTSRYLIAEADESDASFLHLQPMVSVVTNIEADHMDTYGGDFEKLKSTFVDFLHNLPFYGVAVVCIDDAVVREIMPRIGRHMITYGFSDDADVQALNFHQQGHQCRFTVRRKGKEDLDLLLNLPGQHNVLNALAAIAVATEDEIDDSAIIQALAEFQGIGRRFQHLGKFATPKGEVMLVDDYGHHPSEVAATIKAARAGWPDKRLVMAYQPHRYTRTRDLYEDFIEVLSQVDCLLLLEVYSAGEAPIPGADGRALCRSIRLRGQLDPIFIASPDQLAEVLPDVLQEGDLLLTQGAGNIGALSRQLAASELGFSIAATTEVKP
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ETXB_CLOPF
Sequence: MKKNLVKSLAIASAVISIYSIVNIVSPTNVIAKEISNTVSNEMSKKASYDNVDTLIEKGRYNTKYNYLKRMEKYYPNAMAYFDKVTINPQGNDFYINNPKVELDGEPSMNYLEDVYVGKALLTNDTQQEQKLKSQSFTCKNTDTVTATTTHTVGTSIQATAKFTVPFNETGVSLTTSYSFANTNTNTNSKEITHNVPSQDILVPANTTVEVIAYLKKVNVKGNVKLVGQVSGSEWGEIPSYLAFPRDGYKFSLSDTVNKSDLNEDGTININGKGNYSAVMGDELIVKVRNLNTNNVQEYVIPVDKKEKSNDSNIVKYRSLYIKAPGIK
What is the function of this protein?
Responsible for a rapidly fatal enterotoxemia.
What are the official names of this protein?
Epsilon-toxin type B.
What is the protein family that this protein belongs to?
To epsilon-toxin type D.
Protein: RL28_VIBCM
Sequence: MSRVCQVTGKRPAVGNNRSHAKNATKRRFLPNLQTHRFWVESEKRFVKLRLTAKGMRIIDKKGIDAVLVEIRARGENV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: BAP1_XENLA
Sequence: MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCPGPVYGFIFLFKWIEERRSRRKVSTLLDDTSVMEDEVVNNMFFAHQLIPNSCATHALLSVLLNCGGVHLGPTLSRIKEFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGISAVRTMEAFHFVSYVPIKGRLFELDGLKVYPIDHGPWAEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRLKYEGKLNILKMNRQTVLEALQQLIRVTQPELIQAQKSTDGQSTEETKSPAIKAPVSQESHRAHHGSHRSTTDLGAEPAGSLLRGPVLSAHNKSKPLPQNGGIVPAPASRLPAFLDNHNYAKSPMQEEEDLAAGVGRSRGVPPPAPDTDEEEEEETENVRRPLTPPGFKRRSSESLPPPPGPEPGVLAEKLKETQRDLCSPLSIKTGAPTAPHSQPSPTPSNESTDTASEIGSAFNSPLRSPLRSANPTRPSSPVTSHLSKVLFGEEEPLSRLDCVRYNRAVRELGPHISTGILHLSKDGYLSPLSRLDTGKVSPKSHKAEEPRESPEPDSERNRVTEAPQGEKFSPKELLALLKCVEAEISASEACLREELEKRKKIQD
What is the function of this protein?
Deubiquitinating enzyme that plays a key role in chromatin by mediating deubiquitination of histone H2A.  Catalytic component of the PR-DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-119' (H2AK119ub1) (By similarity).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase BAP1, BRCA1-associated protein 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C12 family. BAP1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Mainly nuclear. Binds to chromatin.
Protein: KHPA_LEPIC
Sequence: MEELLKYIVASLVEFPEEIVIREIEGEEQNIIELRVSPKDVGKVIGKNGRIAKSLRAILTAASVKAGKNFSLEIID
What is the function of this protein?
A probable RNA chaperone.  Forms a complex with KhpB which binds to cellular RNA and controls its expression.  Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
What are the official names of this protein?
RNA-binding protein KhpA, KH-domain protein A.
What is the protein family that this protein belongs to?
Belongs to the KhpA RNA-binding protein family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENOPH_DROVI
Sequence: MTIPDLTAKVVLVDIEGTTTSISFVHEVLFPYAKQNAEHYLLETWETDATKQIVQDLQLLPQFAEYASTLGTQPAVDAQLIAGFVRYLIERDLKVTPLKTLQGLIWAKGYASGQLRGHVYEDVATAFHTWREAGLRIAVYSSGSVAAQKLIFQHSIAGDLLPHLSAHFDTHVGHKQQTESYTKISQILQVEPQHVLFLTDVPLEAAAARAAGMLTILLQRPGNVPLSEEERSSYPVVEDFVALHTLKQP
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ACP_BRUA1
Sequence: MSDTAERVKKIVVEHLGVDADKVTEGASFIDDLGADSLDTVELVMAFEEEFGVEIPDDAAETILTVGDAVKFIDKASA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EMC2_BOVIN
Sequence: MAKVSELYDVTWEEMRDKMRKWREENSRNSEQIVEVGEELISEYASKLGDDIWIIYEQVMIAALDYGRDDLALFCLQELRRQFPGSHRVKRLTGMRFEAMERYDDAIQLYDRILQEDPTNTAARKRKIAIRKAQGKNVEAIRELNEYLEQFVGDQEAWHELAELYINEHDYAKAAFCLEELMMTNPYNHLYCQQYAEVKYTQGGLENLELSRKYFAQALKLNNRNMRALFGLYMSASHIASNPKASAKTKKDNMKYASWAASQINKAYQFAGRSKKETKYSLKAVEDMLETLQITQS
What is the function of this protein?
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.  Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues.  Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices.  It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes.  By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins like the G protein-coupled receptors.  By regulating the insertion of various proteins in membranes, it is indirectly involved in many cellular processes.
What are the official names of this protein?
ER membrane protein complex subunit 2, Tetratricopeptide repeat protein 35, TPR repeat protein 35.
What is the protein family that this protein belongs to?
Belongs to the EMC2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=May also localize to the nuclear envelope.
Protein: Y917_YERE8
Sequence: MPKRTYAMRYVAGQPVEQIFPGSAKQLGQGLPPGAPLPTTEFLRVMVWNIFKQQRAQWLSVLKEFGRDAQLMLLQEAQTTPELVRFATSHYQAADQVPAFALPQHPSGVMTLAATHPVYCCPLREREPLLRLSKSALITVYPIHDGRLLMVVNIHAVNFSLGVDVYSKQLEPIGEQIAMHRGPVILAGDFNAWSRQRVNALQRFAQGLGLEEVEFSTDNRSRAFGKPLDFVFYRGLTLADASVLVTRASDHNPLLVEFQP
What are the official names of this protein?
UPF0294 protein YE0917.
What is the protein family that this protein belongs to?
Belongs to the UPF0294 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG20_ASHGO
Sequence: MTEQSEHSNGGVCASSIQPARNGGLCGHGGVGGVGEAEGDPVHTQIIQEDNPFVEHGQSYVAPHSGGGRTSSGSSSSASLQEGLLAPPLAKSSAGEQGRVRILEASKVSEGQGRSYITYTISYRDRVVRRRYSEFESLRKILIKLFPMTLIPPIPEKQSLTSYGKSIAGSNANYVLPSEAAGCDLAVSVINGSVNLNDQKMIRHRIRMLTSFLNRLLQNEEVTKTSIIGDFLDPNNANWNDVITTSATISSLPKSVLQCNPLDPTNTTPAHASLPIPPLSSAPQLMGKDGVGTSTKPSAEDMEFSRIEYEYKKYEQLLHTGVYKYNRRITRTMHELKQDLADLSEAFAEFAVEQSKGGDLAELLSYLSNANDEAAAVLDDLVGKIYYNINEPLSEAVHIAGAARELIQYRRLKFAQRDMLKKSLLGKEGHLKRLQEQEDDAKAIDQLVDQHLGEGTRINLQRPSEASPNTYKRKLFSRFNKLANIVKETVTYQEQDPKVNIKTVQEDIEQIKESLDVSASDLDVITATIRDVQLPAFSRNRDKELYDILKNYSKYMKEYAAKNLEIWKDLRKQEENA
What is the function of this protein?
Required for cytoplasm to vacuole transport (Cvt), pexophagy and mitophagy.  Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress.  Functions in protein retrieval from the endocytic pathway (By similarity).
What are the official names of this protein?
Autophagy-related protein 20.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein. Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: M1_I54A1
Sequence: MSLLTEVETYVLSIVPSGPLKAEIAQRLEDVFAGKNTDLEALMEWLKTRPILSPLTKGILGFVFTLTCPSERGLQRRRFVQNALNGNGDPNNMDKAVKLYRKLKREITFHGAKEVALSYSAGALASCMGLIYNRMGTVTTEVAFGLVCATCEQIADSQHQSHRQMVTTTNPLIRHENRMVLASTTAKAMEQMAGSSEQAAEAMEVASQARQMVQAMRTIGTHPSSSAGLKDDLLENLQAYQKRMGVQMQRFK
What is the function of this protein?
Determines the virion's shape: spherical or filamentous.  Clinical isolates of influenza are characterized by the presence of significant proportion of filamentous virions, whereas after multiple passage on eggs or cell culture, virions have only spherical morphology.  Filamentous virions are thought to be important to infect neighboring cells, and spherical virions more suited to spread through aerosol between hosts organisms.
What are the official names of this protein?
Matrix protein 1, M1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses Matrix protein M1 family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Cytoplasmic side. Host nucleus.
Protein: TRUA_PHOPR
Sequence: MRIALGIEYDGAKYCGWQRQVDVDSVQERLEKALSHIANKPIAVFCAGRTDTGVHGTGQVVHFDVDVDRQMVAWTIGVNAHLPRDISVRWATQVSDDFHARFSATARRYRYIIYNSALRPAIFGVGVSHYHGHLDEKKMHEAAQYLVGEHDFTSVRASQCQSRSPWRAMKHVNVSRQGDFVIIDIKANAFVHHMVRNIAGSLIRVGRGQETPEWMKWVLEQKDRRVAGETAKAAGLYLVAVDYPEEFGLPSSPLGPIFLPD
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: APAM_APIME
Sequence: MISMLRCIYLFLSVILITSYFVTPVMPCNCKAPETALCARRCQQHG
What is the function of this protein?
Neurotoxin that blocks the small-conductance calcium-activated potassium (SK) channels KCa2. 1/KCNN1/SK1, KCa2. 2/KCNN2/SK2 and KCa2. 3/KCNN3/SK3 (PubMed:6122211, PubMed:9459560, PubMed:9287325, PubMed:10696100, PubMed:11533126, PubMed:11212219, PubMed:17142458, PubMed:20562108, PubMed:32560481).  Also irreversibly blocks the voltage-gated potassium channel Kv1. 3/KCNA3 (IC(50)=13 nM) (PubMed:28108814).  Potently blocks human, rat and mouse KCa2. 2/KCNN2/SK2 channels (IC(50)=27-140 pM), and moderately blocks human and rat KCa2. 3/KCNN3/SK3 channels (IC(50)=0. 6-4 nM), and human (IC(50)=0. 7-12 nM) and mouse (IC(50)=28 nM) KCa2. 1/KCNN1/SK1 channels (PubMed:9459560, PubMed:9287325, PubMed:10696100, PubMed:11533126, PubMed:11212219, PubMed:17142458, PubMed:20562108).  However, other reports found that it did not block the human KCa2. 1/KCNN1/SK1 channels (PubMed:9287325).  Also able to inhibit neuromuscular transmission by a mechanism independent of the blockade of SK channels, which may involve the activation of inhibitory muscarinic M2 receptors on motor nerve terminals (PubMed:19818752).
What are the official names of this protein?
Apamin, APM, Apamine.
What are the subcellular locations of this protein?
Secreted.
Protein: CH60_TRIVA
Sequence: MSLIEAAKHFTRAFAKARDLKFGSDARDHLLLGVEKLADAVVSTLGPKGRNVMIELPYGPPKVTKDGVTVAKSIEFKDKWQNLGAQLVINVAQKTNDVAGDGTTTATLLTRELYRESIKALSAGLDPNKVRKGMTLRVDAVVKELEKSTKKVSSPDEIFNVATISANGSEKIGHLIADAFKAVGNEGVITVAMGKKFDHELETVQGMKIDRGYISSYFQNDTKSMKCEYENPYILITDIKINSFAQIAPILEKIITTGRPLLIIADDVEGDALATLIVNKIRGSLKVVAIRAPGFGDNKKNTLQDIAVATGGQYISEELGLKLEEATQQMLGQCNKITVSKDDCIILGGAGDKDAMKARSEDIKKQLSNTQSKYETDKLRERLAKLTGGVAVISVGGANEVEVGEEKDLIDDALNATRAAIEEGIVAGGGTALLRASAVLEPLKKDKGLEERTGIEIIQNSHQTASHSHC
What is the function of this protein?
Implicated in hydrogenosomal protein import and macromolecular assembly.  May facilitate the correct folding of imported proteins.  May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the hydrogenosome (Potential).
What are the official names of this protein?
Hydrogenosomal chaperonin HSP60, Protein Cpn60, Heat shock protein 60, groEL protein.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Hydrogenosome.
Protein: NAMA_BACCQ
Sequence: MNYKLFSPYTIKDVTLKNRIVMSPMCMYSSKNEDGQITNFHLIHYGTRAAGQVGLVMIEATAVLPEGRISNKDLGIWDDSLIEGLHKATTFIHDNGAKAAIQLAHAGRKAELETDALAPSAIPFNETMKMPIEMSKHQIKDTVLAFQQAAVRSKQAGFDVIEIHGAHGYLINEFLSPLTNKRTDEYGGSPENRYRFLREIIESINEVWNGPLFVRISANDYHPDGLTVQDYVQYTKWMKEQGVDLIDCSSGAVVPARIDVYPGYQVQYAKHIKEHANIATGAVGLITTGAQAEQILNNNEADLIFIGRELLRNPYFPRIAANELGFELEEPYQYERAPGKISTNK
What is the function of this protein?
Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones.  It also reduces the nitro group of nitroester and nitroaromatic compounds.  It could have a role in detoxification processes.
What are the official names of this protein?
NADPH dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily.
Protein: EPO_EPICO
Sequence: MLQKRGRGLLVLLLMLLEWTRPGLLSPLRPICDLRVLNHFIKEARDAEVAMKSCTEGCSLSESVTVPQTRVDFDVWEKKNGLEQAQEVQSGLWLLQQALNLLRTSVTNTALHSHIDNSIRNLLSINAVLRSLNIQEYTPPASTVALEGTWRVSSATDLLQVHVNFLRGKVRLLLLDAQACQQDVS
What is the function of this protein?
Erythropoietin is the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass.
What are the official names of this protein?
Erythropoietin.
What is the protein family that this protein belongs to?
Belongs to the EPO/TPO family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL29_CROS8
Sequence: MKAKELREKSVEELNTELLNLLREQFNLRMQAASGQLQQTHLLKQVRRDVARVKTLLTEKAGA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: Y193_BPT7
Sequence: MATPIRPLSYSLRRQSNGESRRLSTRVTSVTVCSVRYSVLSFLNTTTVRWKRFVPVV
What are the official names of this protein?
Protein 19.3, Gene product 19.3, Gp19.2.
Protein: PEX13_DICDI
Sequence: MRRSPPKPWENNSGGGGSTSMTGSGGISRPMSGPQRTTSPGGGSSTTTQTSTLNNTGSPSTSVGGPLVTRPRTPMRPWESGGAGSSSIDSFGGGVGGSSGYRSSYGGGYRDSYSSGGYGSSGYGSSYGSGGSGGYGSSLYGGGGYSSGGYGGSGYGSSYGGGYGSSYGSGYGSSYGGSGYGSSYGGGYGSSYGGGYGGGYGGGYGQRGYDNMDGKGGALQSVVSSGHSWMEALHSIVDTFSRFSRLLDANFDAVHGSFSSIIRLCQSMSHFSYEIMAIIKTYSLFRMFQSVASRFLRVFRYLLGKKSKSNSSNNNTSSKFGSNAITESLRQANMDVSDFRNFQNEKKQSVGTLILIIAATFIGVPMVIGQLLNLRRRGQASRLDKGWEEQQGGGYGQVKAIYEFNPETTRDLPLRVGDIVNVIDKPHDNWWVGECNGLSGFFPVDFTEKISPNDINNNNNNNNNNNNNINTSVQIYDNNNGFNRNNSNNNLNNSEYSDYSSSNNNNNNNNNNNNNSNYQLQSNFSSNNDGISKNIIYNNNNDNQRPISPSKTSQQLSRSELMDKPYVEES
What is the function of this protein?
Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor (By similarity).  The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm (By similarity).  Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix (By similarity).
What are the official names of this protein?
Peroxisomal membrane protein PEX13, Peroxin-13.
What is the protein family that this protein belongs to?
Belongs to the peroxin-13 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Single-pass membrane protein.
Protein: GCST_SALPB
Sequence: MAQQTPLYEQHTLCGARMVDFHGWMMPLHYGSQLDEHHAVRTDAGMFDVSHMTIVDLHGSRTREFLRYLLANDVAKLTKTGKALYSGMLNASGGVIDDLIVYYFTEDFFRLVVNSATREKDLSWITQHAEPYAIDITVRDDLSLIAVQGPNAQEKAATLFTEQQRHAVEGMKPFFGVQAGDLFIATTGYTGEAGYEIAMPNEKAADFWRALVEAGVKPCGLGARDTLRLEAGMNLYGQEMDEGISPLAANMGWTIAWEPADRDFIGREALEMQREKGHEQLVGLVMTEKGVLRNELPVRFTDAQGNQQEGIITSGTFSPTLGYSIALARVPAGIGETAIVQIRNREMPVKVTKPVFVRNGKAVA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: TILS_PROMT
Sequence: MRLHKRLKQNKSLLPSNSTILLAISGGQDSMALLKLIIDLKRLHQWQVEVWHGNHQWHAKSEETEDELKLWCLKNQISFHSNKADKKEVANEEKARDWRYKNLIMKAKFLSSKNIHFPCTRILTGHTATDRAETVIMNLARGTDLTGLTTLKEQRTIENNIDLTRPLLIFNRNETLEICKDFNLPIWIDPSNENINLTRNKIRKEILPILNSIYKGADSRIASVANRLESYNEDQKLFAKIAIQFCQGEKINSLSRIKLFGLTNSIRQIILSNWLKTMGVKRVTALQIEEINTKVSQRKPPGSIHLHGDFLIRWNKEAIYISNKTN
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FDL37_ARATH
Sequence: MVKTEICGKGSSQGSEEERLSQLPDHLICVILSHLSTKDAVRTSILSTRWRNLWQLVPVLDFDSRELRSFSEFVSFAGSFFYLHKDSYIQKLRVCIYDLAGNYYLTSWIDLVTRHRIQHIDISVFTCSGFGVIPLSLYTCDTLVHLKLSRVTMVNVEFVSLPCLKILDLDFVNFTNETTLDKIISCSPVLEELTIVKSSEDNVKIIQVRSQTLKRVEIHRRFDRHNGLVIDTPLLQFLSIKAHSIKSIEFINLGFTTKVDIDVNLLDPNDLSNRSMTRDFFTTISRVRSLVIRHGTIKDIFHYMELEPLQQFCYLSELSAVCSISNLEMLLNLLKSCPKLESLSLKLVDYEKNKKEEVMSSTVPPPCLVSSLKFVKLESQLLGCGTELKVARYFLENSTILEKLTLKIDYMYKDEANVNHIRQTLHAVPRCSSTCEVVIHSLLY
What are the official names of this protein?
F-box/FBD/LRR-repeat protein At5g53840.
Protein: F167A_HUMAN
Sequence: MSVPQIHVEEVGAEEGAGAAAPPDDHLRSLKALTEKLRLETRRPSYLEWQARLEEHTWPFPRPAAEPQASLEEGERGGQEPLLPLREAGQHPPSARSASQGARPLSTGKLEGFQSIDEAIAWLRKELTEMRLQDQQLARQLMRLRGDINKLKIEHTCRLHRRMLNDATYELEERDELADLFCDSPLASSFSLSTPLKLIGVTKMNINSRRFSLC
What are the official names of this protein?
Protein FAM167A.
What is the protein family that this protein belongs to?
Belongs to the FAM167 (SEC) family.
Protein: RL18_ECO27
Sequence: MDKKSARIRRATRARRKLQELGATRLVVHRTPRHIYAQVIAPNGSEVLVAASTVEKAIAEQLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYHGRVQALADAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: TAL_METJA
Sequence: MKFFLDTANVEEIKKYAELGLVDGVTTNPTLVAKEGRDFYEVVKEICEIVEGPVSAEVISTDAEGMVKEARELAKLADNIVIKIPMTKDGMKAVKILSAEGIKTNVTLVFSPLQALVAAKAGATYVSPFVGRLDDIGHVGMKLIEDVVKIYKNYDIKTEVIVASVRHPWHVLEAAKIGADIATMPPAVMDKLFNHPLTDIGLERFLKDWDEYLKSRK
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YKOM_BACSU
Sequence: MMRLSFNEEEVERAMNLYRVFARAFKSVSEHSIRDSKEHGFNPTEFAVLELLYTRGPQKLQQIGSRLLLVSGNVTYVIDKLERNGFLVREQDPKDKRSVYAHLTDKGNEYLDKIYPIHALRIARAFSGLSPDEQDQLIVLLKKAGIHSQHLLFR
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator YkoM.
Protein: RK16_ZYGCR
Sequence: MLSPKRTRFRKQHRGRLKGISTRGNRICFGRFGLQALEPSWITSRQIEAGRRAITRYARRGGKLWIRIFPDKPITMRPAETRMGSGKGSPEYWVAVVKPGRILYEMSGVSETIARAAMRIAAFKMPIKTQFIKTPVLATIQ
What are the official names of this protein?
50S ribosomal protein L16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.