PharMolix/UniProtQA huggingface dataset:
Protein: RIFK_LODEL
Sequence: MTRPETIIPEKPTSPYPIHTTAPIISGFGRGSSELGIPTANIPINAQLNSLPTGIYYGWCKIHPVSDQNDETRTRPDGQLILFNHGNKLQANELVVHPMVMSIGWNPFYQNKEKAAEIHIMSKFERDFYGAELEFIVLGYVRPELDYTTKEALIEDILTDIRISRDILENKEEYTKYKKELE
What is the function of this protein?
Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme.
What are the official names of this protein?
Riboflavin kinase, Flavin mononucleotide kinase 1.
What is the protein family that this protein belongs to?
Belongs to the flavokinase family.
Protein: RLMH_LACLS
Sequence: MKIKLVVVGKLKEKYLKDGIAEYVKRMGTMLPLEIIELADEKIPDNASEKEAEALKKREGDKILSRIQTGDKLAILAIQGKLMSSEELADFVKKAEVYGTGNLVFVIGGSLGLSDEVYKRSDLQISFGRMTLPHQLMRLVLVEQIYRAQMINRGSAYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPE23_MYCTU
Sequence: MTLDVPVNQGHVPPGSVACCLVGVTAVADGIAGHSLSNFGALPPEINSGRMYSGPGSGPLMAAAAAWDGLAAELSSAATGYGAAISELTNMRWWSGPASDSMVAAVLPFVGWLSTTATLAEQAAMQARAAAAAFEAAFAMTVPPPAIAANRTLLMTLVDTNWFGQNTPAIATTESQYAEMWAQDAAAMYGYASAAAPATVLTPFAPPPQTTNATGLVGHATAVAALRGQHSWAAAIPWSDIQKYWMMFLGALATAEGFIYDSGGLTLNALQFVGGMLWSTALAEAGAAEAAAGAGGAAGWSAWSQLGAGPVAASATLAAKIGPMSVPPGWSAPPATPQAQTVARSIPGIRSAAEAAETSVLLRGAPTPGRSRAAHMGRRYGRRLTVMADRPNVG
What are the official names of this protein?
Uncharacterized PPE family protein PPE23.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PPE family.
Protein: GLMS_NEIMB
Sequence: MCGIVGAIRAHHNVVDFLTDGLKRLEYRGYDSSGIAVNTDGKIKRVRRVGRVQLMEDAAREKGISGGIGIGHTRWATHGGVTEPNAHPHISGGMIAVVHNGIIENFESERKRLEGLGYRFESQTDTEVIAHSINHEYAQNGGRLFEAVQEAVKRFHGAYAIAVIAQDKPDELVVARMGCPLLVALGDDETFIASDVSAVIAFTRRVAYLEDGDIALLASDGIKRLTDKNGLPAERKVKVSELSLASLELGLYSHFMQKEIHEQPRAIADTAEVFLDGGFIPENFGKDAKSVFESIRSVKILACGTSYYAALTAKYWLESIAKIPSDVEIASEYRYRSVIADSDQLVITISQSGETLDTMEALKYAKSLGHRHSLSICNVMESALPRESSLVLYTRAGAEIGVASTKAFTTQLVALFGLAVTLAKVRGLVSEEDEARYTEELRQLPGSVQHALNLEPQIAAWAQQFAKKTSALFLGRGIHYPIALEGALKLKEITYIHAEAYPAGELKHGPLALVDENMPVVVIAPNDSLLDKVKANMQEVGARGGELFVFADLDSNFNATEGVHVIRAPRHVGKLSPVVHTIPVQLLAYHTALARGTDVDKPRNLAKSVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS21_CAMFF
Sequence: MPGVKVHPNESFDEAYRRFKKQTDRNLVVTEVRARRFFEPMTEIRKKQKISARKKMLKRLYMLRRYESRL
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: HLDD_DESVH
Sequence: MYIVTGGAGFIGSAMVWKLNEMGIEDIVVVDNLSTSEKWKNLVNRRYVDYVHRDTFMDMVLHGDLPWDVDAVVHMGACSATTERDADFLMENNLRYSRMLCELCMETGARFINASSAATYGDGSLGFSDDDTTMLRLKPLNMYGYSKQLFDLWAYREGRLDGIASLKFFNVYGPNEYHKGDMRSVICKAYAQIGQEGVMRLFRSCHPDYADGGQMRDFIYVKDCVEVMWWLLQNPGVNGVFNVGTGKARTWNDLVTAVFRAMDREPVIEYIDMPEQLRGKYQSFTEATMGKLRDAGCPVRFTELEDGVTEYVRRYLAAADPHL
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: SFRP2_HUMAN
Sequence: MLQGPGSLLLLFLASHCCLGSARGLFLFGQPDFSYKRSNCKPIPANLQLCHGIEYQNMRLPNLLGHETMKEVLEQAGAWIPLVMKQCHPDTKKFLCSLFAPVCLDDLDETIQPCHSLCVQVKDRCAPVMSAFGFPWPDMLECDRFPQDNDLCIPLASSDHLLPATEEAPKVCEACKNKNDDDNDIMETLCKNDFALKIKVKEITYINRDTKIILETKSKTIYKLNGVSERDLKKSVLWLKDSLQCTCEEMNDINAPYLVMGQKQGGELVITSVKRWQKGQREFKRISRSIRKLQC
What is the function of this protein?
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts.  They have a role in regulating cell growth and differentiation in specific cell types.  SFRP2 may be important for eye retinal development and for myogenesis.
What are the official names of this protein?
Secreted frizzled-related protein 2, FRP-2, sFRP-2, Secreted apoptosis-related protein 1, SARP-1.
What is the protein family that this protein belongs to?
Belongs to the secreted frizzled-related protein (sFRP) family.
What are the subcellular locations of this protein?
Secreted.
Protein: HUTI_METS4
Sequence: MLCDRLWRNARLATLAEGAPGLGLVEDGLIAARDGRILYAGPARAAPAFAARETVDCEGRWITPGLIDCHTHLVHGGDRAAEFEARLAGASYEEIARAGGGIVSTVRATRAASEDALVGSALRRLDALIAEGVTAVEVKSGYGLSVASERASLRAARRLGESRDVTVTTTFLGAHALPPEEPDKDRYIAHVCTEMLPALAREGLADAVDAFCEGIAFSPAQTARVFEAARAAGLPVKLHADQLSDLGGAALAARFGALSADHLEYADEAGAAALARAGTVAVLLPGAFYFIRETRRPPVDLFRRHGTRMALATDCNPGTSPLTSLLLVLNMGATLFRLTVEECLAGVTREAARALGRLHEIGTLEAGKWCDLAVWDVERPAELVYRMGFNPLHARIRRGR
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXR_CUPNH
Sequence: MHRITILGATGSIGESTLDVVRRHADRYVVHALTAHRQVRKLADQCVEFRPARAVVGTAEAALELETLLRDAGVKTEVSHGEAALESVAADAQTDSVMAAIVGAAGLRPTLAAARAGKRVLLANKEALVMSGRIFMDAVREHGATLLPIDSEHNAIFQCLPADDPRYGRGVARVLLTASGGPFRTRDPATLHDISPDQACAHPNWVMGRKISVDSATMMNKGLEVIEAHWLFGAPAERIEVLIHPQSIVHSMVAYTDGSVLAQLGNPDMRTPIAYGLAYPERIDAGVTPLDLTVAGGLHFEKPDLVRFPCLGLAFDALRAGGVAPAALNAANEVAVEAFLGGTVRFTDIAGIVRQVLEATPQGPADTLEAVLSADALAREAAREGVAALAAKR
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: PRVA_ESOLU
Sequence: AKDLLKADDIKKALDAVKAEGSFNHKKFFALVGLKAMSANDVKKVFKAIDADASGFIEEEELKFVLKSFAADGRDLTDAETKAFLKAADKDGDGKIGIDEFETLVHEA
What is the function of this protein?
In muscle, parvalbumin is thought to be involved in relaxation after contraction.  It binds two calcium ions.
What are the official names of this protein?
Parvalbumin alpha, Parvalbumin III, Parvalbumin pI 5.0, Parvalbumin-3.
What is the protein family that this protein belongs to?
Belongs to the parvalbumin family.
Protein: NTRC_AZOC5
Sequence: MPTGSILVADDDAAIRTVLNQALSRAGYEVRSCGNAATLWRWVSQGDGDLVITDVVMPDENAFDLLPRIKKARPDLPVIVMSAQNTFMTAIRASERGAYEYLPKPFDLKELISIVGRALAEPKKAEKLALGSDEQENIPLVGRSAAMQEIYRLLARLMQTDLTVMIAGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGSFTGATTRNAGRFEQAEGGTLFLDEIGDMPMEAQTRLLRVLQQGEYTTVGGRTPIKTDVRIIAATNKDLRTLIQQGLFREDLFFRLNVVPLRLPPLRERSEDVPDLVRHFFLQAEREGLPAKQVDSAALDRLKRYRWPGNVRELENLVRRLAALYPQEIITPSIIEAELSEPAPSALSEDGPVDATLGASVERHLNGYFSGFGEDLPPPGLYHRILRDVEYPLLSAALAATRGNQIKAAELLGLNRNTLRKKIRDLDIQVIRTSR
What is the function of this protein?
Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation.  Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.
What are the official names of this protein?
DNA-binding transcriptional regulator NtrC, Nitrogen regulation protein NR(I), Nitrogen regulator I, NRI.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FDHD_SALNS
Sequence: MNNILSEEVLNVTDFTTSRQLTLWKREDLQSPQLDDVAEEVPVALVYNGISHVVMMASPKDLTHFAMGFSLSEGIIDSPREIYGMDVVPSCNGLEVQIDLSSRRFMGLKARRRALAGRTGCGVCGVEQLNDIGKPVQPLPFSQTFNLGNLDRALKHLNDFQPTGKLTGCTHAAAWVMPSGELAGGHEDVGRHVALDKLLGRRATEGEEWRQGAALVSSRASYEMVQKSAMCGVEILFAVSAATTLAVEVAERCNLTLVGFCKPGRATIYTHPQRLIAD
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity.  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
What are the official names of this protein?
Sulfur carrier protein FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YNYB_SCHPO
Sequence: MLKCTIKNEQIETLRSGDTFVSYEIETESDLPVFEDKKFSVRRRYKDFEMLHNILSHDYNGYAIPPLPRKYTVSSFSGGSLSPIFIARRMQSLQTFLDRCSTHPVISNSMHMYQFLENNSWKSYYHNAWMQSENTKSKGNNVSGGIESSIQNLDPYAQSLYETAKQLLQNADTDLSKLEKTCVQYMNSVQNFPTDIPVPSNLSISNLDVVSVEFKRLKRNSIFLINSFHSKVITSIQDLEDYMVVFKSLIKSREQKVKQFEHFQQIVQSNSNNPDQSSRSDPNFVEATPVVQQTPELKPSPNTTIRTSSLFSIPKFFKKKRYSLGQDDANPMELLQLSFQELCIFNEKLEQELNFLRERIDVEMRKTLQMVCDCHVEYFSGILEQHAVKE
What are the official names of this protein?
Sorting nexin C1711.11.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: UDPE_NPVMB
Sequence: MGHLHIVHWRLTMNGAIAALFLCLVMVHQQHAVRILAVFPTPAYSHHSVFKVYIEALAERGHDVVVIKSTDRINYANRNGLRGNVSEIDASLSQEYYGRLMRHAGVFRKRGIVADSSTVTAHNYMGLVRMMSDQFDLPIVKSFIEEAHKHKFDLLITEAYIDYPLVFSHLFGDLPVVQISSGYAVAENFETMGAVSRHPVYYPNLWRDKFSGLNVWKQSMKCTLSWRYRMNLVNWPDEQNALLKRQFGESTPTIQELRNRVELLFVNTHAIFDNNRPVPPSVQYLGALHLHDKRPDSMYGMVREFLDNATTGAIYVSFGSAISSEDMEPEFIEMLLRVFEKLPYSILWKYDGYMNRMPANVFVQSWFEQYNLLHHKNVRAFVTQGGVQSTDEAVEAIVPMVGMPMMGDQAYNMNKIVELGLGKVVDTVRVNAEQLIEAIVDVAESPKYRKRLRELRHMIHHQPMTPLQKAVWYTEHVIESRRRVVPTMLKTRAANVNYSDYIMSYVFVPFIMFTVMNHLRQLLKMNMV
What is the function of this protein?
Catalyzes the transfer of glucose from UDP-glucose to ecdysteroids which are insect molting hormones.  Expression of egt interferes with normal insect development and block molting (By similarity).
What are the official names of this protein?
Ecdysteroid UDP-glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: ISPF_ENTFA
Sequence: MIRIGQGFDVHQLVPQRPLIIGGVTLPYEKGLLGHSDADVLTHAIIDAILGAAGLGDIGQLFPETDPQFKNANSVNLLKKVNEKVGRSGFTIGNIDCTILAEEPKMSPYLAEMKKNLAASCHLAVTQVNIKATTMETMGFVGKKEGIGAIAVALLEK
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: ATPA_CYAM1
Sequence: MVNLRPDEISSMIRQQIEQFSQQVQFNHVGTVMQVGDGIARVYGLNDVMAGELLEFADGTIGIALNLESDHVGAVLMGDGRNILEGSEVKSSGQIAQVPVGEELLGRVVNALVQPIDGKGGIETKQTRLIESPAPGIVARQSVCEPLQTGITAIDAMIPIGRGQRELIIGDRQTGKTAIALDTIINQKNEDVICVYVAIGQKASSVAAAVNLLATKGAMDYTIVVTANADDAASLQYLAPYTGAAIAEHFMYQGKATLVIYDDLTKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNKELGGGSMTALPIVETQAGDVSAYIPTNVISITDGQIFLSSDLFNAGIRPAINVGISVSRVGSAAQIQSMKKVAGRLKLELAQFDELQAFSQFASDLDKATQMQLARGQRLREVLKQSQASPIPIEEQIAMIYAGVNGWLDKLALEEVQPFLSRVRSELRTSNYPSAVKSKWSEEVEQMLKDVLSKHAQ
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, chloroplastic, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: ZN570_HUMAN
Sequence: MAVGLLKAMYQELVTFRDVAVDFSQEEWDCLDSSQRHLYSNVMLENYRILVSLGLCFSKPSVILLLEQGKAPWMVKRELTKGLCSGWEPICETEELTPKQDFYEEHQSQKIIETLTSYNLEYSSLREEWKCEGYFERQPGNQKACFKEEIITHEEPLFDEREQEYKSWGSFHQNPLLCTQKIIPKEEKVHKHDTQKRSFKKNLMAIKPKSVCAEKKLLKCNDCEKVFSQSSSLTLHQRIHTGEKPYKCIECGKAFSQRSNLVQHQRIHTGEKPYECKECRKAFSQNAHLVQHLRVHTGEKPYECKVCRKAFSQFAYLAQHQRVHTGEKPYECIECGKAFSNRSSIAQHQRVHTGEKPYECNVCGKAFSLRAYLTVHQRIHTGERPYECKECGKAFSQNSHLAQHQRIHTGEKPYKCQECRKAFSQIAYLAQHQRVHTGEKPYECIECGKAFSNDSSLTQHQRVHTGEKPYECTVCGKAFSYCGSLAQHQRIHTGERPYECKECKKTFRQHAHLAHHQRIHIGESLSPPNPVNHQVL
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 570.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DPF1_CAEEL
Sequence: MTAEADLLEGYDEELGGNESQKRDCKGITTAIVVVLLILVMIFAALVFFTPLFAAKSFGSWRLNVSDLRSLRYPYAEFAFTDNNAVVMQSWEGVEIVEDGVSRLIFGRENGAEITPSADRKYFAMMDHAPNPGMNPQNETFHLKIVNNNERLNPLLPFEVEELFRELSDSRITYDIGLRKEESVIQAFKWNGKFNDFVFVESNKIYYQSSPEEEGLTRVSNGGEHTVDGLFDWIYEEEIFGRKDAMWWSTKGDQLAYASYDNHLTKNVSLKTYHRLEPYPIDTNFHYPKTFAKVLPTYTLSIWNKKTEQSRQLDVQLKDSLSYHYLLAVKWLEINGTEQLVSVWTNRYQNEVALTICDWDTAICRLEFEYKYASKRWVTHDDFHSITSFEDTLFFLLPHDKRDNAFQQVASLRLSHGQLRTPKFLNLGEYDVTSINGINKETRTIFFHAAAPKPSHRSLFSYSLADESRNSAYCISCSIKNCTWAQAQMDDQMKTAIVSCKGPAAPHTAIVNLTRMDSDKKTEHANLLYDKTYQNRVEEAGLPVIIKETIKISDDFDALIKLSIPKDIYNRDKHQAIPLIVHVYGGPNDQNTKEATQIGIEEVVASASQAAILRIDGRGSGGRGWKYRSAIYGQLGTVEVEDQIKAIKVVLRLYRHLLDARRVAVFGWSYGGFMTLSMVNEAPEQFFKCAVSVAPVTNFAYYDATYTERYMGDAPLESYSDVTKKLDNFKSTRLLLMHGLLDDNVHFQNSAILIDELQNRGVDFDLMVYPNQAHSLSSRTSHVVGKMTHFLRQCFYTDK
What is the function of this protein?
Removes N-terminal dipeptides sequentially from polypeptides (By similarity).  Essential for control of distal tip cell migration.
What are the official names of this protein?
Dipeptidyl peptidase family member 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S9B family. DPPIV subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: CM31_CONTU
Sequence: MSKLGVLLTICLLLFPLTALPMDGDEPADRPAERMQDNISSEQHPLFEERHGCCKGPEGCSSRECRPQHCCGRR
What is the function of this protein?
Mu-conotoxins block voltage-gated sodium channels (Nav) (By similarity).  In vitro, this synthetic peptide displays a low blocking effect in mouse extensor digitorum longus muscles (IC(50)=616 nM).
What are the official names of this protein?
Mu-conotoxin-like T3.1.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL30_METMJ
Sequence: MYAVVQVRGVVKTNHEIKDTLKMLRLHHVNHCVLVPDTPAYLGMIRKVKDFVAYGEVDKDTLATLLRTRGRLTGDEKLTDEYVRAHTPYADIDEFAAALCDGEMSFRDLVEIKPVLRLHPPRKGYKTIKRTFQQGGALGYYGPQINDLLYKMR
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: LIAS_DROER
Sequence: MFGMLRALKTHVEAPIVVATRAVSTNAEKLEEIRERLAKGPNFQDFVQNPENSRSEWEKYEGKLRREKGEEQRLRLPPWLKTTIPVGKNYAKIKAQMRELKLSTVCEEARCPNIGECWGGGEHGTQTATIMLMGDTCTRGCRFCSVKTARRPPPLDVNEPVNTATAIASWGLDYIVLTSVDRDDLPDGGSKHIAETVREIKARNSNIFVECLVPDFRGNLECVETIANSGLDVYAHNIETVEKLTPYVRDRRAHYRQTLQVLTEAKRFNPNLITKSSIMLGLGETDGEIECTLKDLREAGVDCVTLGQYMQPTNKHLKVIEYVTPEKFKHWEERGNALGFLYTASGPLVRSSYKAGEFFITSILENRKKRQNATEIAKE
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, mitochondrial, Lipoate synthase, LS, Lip-syn, Lipoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: VATF_FUSNN
Sequence: MKLMYKIAVIGDKDSVLAFKILGVDVFITLDAQEARKTIDRIAKENYGIIFVTEQLAKDIPETIKRYNSEIIPAVILIPSNKGSLNIGLTNIDKNVEKAIGSKIM
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit F, V-ATPase subunit F.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase F subunit family.
Protein: GPMA_BORT9
Sequence: MYKLVLVRHGESEWNKENLFTGWTDVKLSEKGISEALEGGRVLKQEGYSFDIAFSSVLVRANDTLNIILRELGQSYIDVEKSWRLNERHYGALQGLNKAETAEKYGEDKVLMWRRSYDIPPMPLEESDKRHPIHDLRYRGIPKSELPSTECLKDTVARVIPYWTDKIARAIIEGKKVIIAAHGNSLRALVKYLDNMSDDDILKLNIPTGIPLVYELDRDLRPIKHYYLGDEDKIKAAMESVANQGKKK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: PGAP4_RAT
Sequence: MTTSTSPAAMLLRRLRRLSWGSTAVQLFILTVVTFGLLAPLACHRLLHSYFYLRHWHLNQMSQDFLQQSLKEGEAALHYFEELPSANGSVPIVWQATPRPWLVITIITVDRQPGFHYVLQVVSQFHRLLQQCGPQCEGHQLFLCNVERSVSHFDAKLLSKYVPVANRYEGTEDDYGDDPSTNSFEKEKQDYVYCLESSLQTYNPDYVLMVEDDAIPEEQIFPVLEHLLRARFSEPHLQDALYLKLYHPERLQHYINPEPMRILEWVGVGMLLGPVLTWIYMRFACRPGFSWPVMLFFCLYSMGLVELVGRHYFLELRRLSPSLYSVVPASQCCTPAMLFPAPAARRTLTYLSQVYCHKGFGKDMALYSLLRAKGERAYVVEPNLVKHIGLFSSLRYNFHPSLL
What is the function of this protein?
Golgi-resident glycosylphosphatidylinositol (GPI)-N-acetylgalactosamine transferase involved in the lipid remodeling steps of GPI-anchor maturation.  Lipid remodeling steps consist in the generation of 2 saturated fatty chains at the sn-2 position of GPI-anchors proteins.  Required for the initial step of GPI-GalNAc biosynthesis, transfers GalNAc to GPI in the Golgi after fatty acid remodeling by PGAP2.
What are the official names of this protein?
Post-GPI attachment to proteins factor 4, Post-GPI attachment to proteins GalNAc transferase 4, Transmembrane protein 246.
What is the protein family that this protein belongs to?
Belongs to the PGAP4 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: Y411_BUCBP
Sequence: MSFDEIKTHNKKAIIGIFMIFSLRVFGMFMIVPVLSTYGMCLKNSNIFLVGVAIGIYGIFQIIFQIPYGWLSDKYGQKLIINIGLLCFLLGNIIAWSSNSIWGIILGRGLQGSGAISSVCMTLLSELVLPHNRIKIMGLLGVSFGISFFLAVILSPIIVNMFGFYCLFLINSLLSIFCLFFGMFYIPASLLNKNVVCNFRSEISNFFKILSNRVLCQINLSVFLIHFFLMCNFIIIPVELKKIFEFFEYVPEIIYIVILLVSFLIVLFCICFIQSKVLYSNITITTSAFLFVLCYGIFLLFGHNNISLILGLQIFFIAFIFLETILPALVNKFSSKNYKSTTMAIYSTSQFLGSSMGGIIGGILFSYLNYFEVLFFEFVVSILWFITSILYLIK
What are the official names of this protein?
Uncharacterized transporter bbp_411.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GPR61_MOUSE
Sequence: MESSPIPQSSGNSSTLGRALQTPGPSTASGVPELGLRDVASESVALFFMLLLDLTAVAGNAAVMAVIAKTPALRKFVFVFHLCLVDLLAALTLMPLAMLSSSALFDHALFGEVACRLYLFLSVCFVSLAILSVSAINVERYYYVVHPMRYEVRMTLGLVASVLVGVWVKALAMASVPVLGRVYWEEGAPSVNPGCSLQWSHSAYCQLFVVVFAVLYFLLPLILIFVVYCSMFRVARVAAMQHGPLPTWMETPRQRSESLSSRSTMVTSSGAHQTTPHRTFGGGKAAVVLLAVGGQFLLCWLPYFSFHLYVALSAQPISAGQVENVVTWIGYFCFTSNPFFYGCLNRQIRGELSKQFVCFFKAAPEEELRLPSREGSIEENFLQFLQGTSENWVSRPLPSPKREPPPVVDFRIPGQIAEETSEFLEQQLTSDIIMSDSYLRPAPSPRLES
What is the function of this protein?
Orphan G-protein coupled receptor.  Constitutively activates the G(s)-alpha/cAMP signaling pathway (By similarity).  Shows a reciprocal regulatory interaction with the melatonin receptor MTNR1B most likely through receptor heteromerization (By similarity).  May be involved in the regulation of food intake and body weight (PubMed:21971119).
What are the official names of this protein?
G-protein coupled receptor 61.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Note=Colocalizes with ARRB2/beta-arrestin-2 in the endosome (By similarity).
Protein: FABZ_XANCP
Sequence: MSHPIYELPIDVNQIQTLIPHRYPFLLIDRVIELDLEAKRIVGQKNVTINEPFFQGHFPTRPVMPGVLIIEALAQAGGVMTQLGLGRDALSKLFYMVKVDNARFNKQVVPGDVLILEVQMKRLIRNMGCYYGEAKVNGEIVASAEVMCAGARE
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRHO_BACLD
Sequence: MKNQYRVLLYYKYVHIDNPEQFAEDHLKFCKDLGLKGRILVAGEGINGTVSGTVEQTDRYMSEMKSDPRFEDMVFKIDESEGHAFKKMHVRHRDELVTLRLEDDIDPNELTGKYLEPKEFYEAMQQEDTIVVDARNDYEYDLGHFRGAIRPDIKAFRELPEWIRDNKEKLEGKKILTYCTGGIRCEKFSGWLKKEGFEDVSQLHGGIVTYGKDPEVQGELWDGKCYVFDERISVPVNQKEHVIVGKDYFTGEPCERYVNCANPECNKQIICSEENEHRYLRGCTHECRVHPRNLYVKEHGLSEEEVQERLEKLKEEEHAAQS
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: RS13_BACTN
Sequence: MAIRIVGVDLPQNKRGEIALTYVYGIGRSSSAKILDKAGVDKDLKVKDWTDDQAAKIREIIGAEYKVEGDLRSEIQLNIKRLMDIGCYRGVRHRIGLPVRGQSTKNNARTRKGRKKTVANKKKATK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: NRDR_HAEIN
Sequence: MHCPFCDTEETKVIDSRLVSDGYQVRRRRECGHCHERFTTFEMAELIIPKIIKTDGTREPFNEDKLRSGIQHALEKRPVSADDVEKAINHIILQLRATGEREVPSKLVGKLAMNELKKLDKVAYIRFASVYLSFDDIDQFTIEIEKLKD
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.