PharMolix/UniProtQA huggingface dataset:
Protein: TIG_BACCN
Sequence: MAAKWEKLEGNVGVLTIEVDAKEVNKSLDAAFKKVVKTINVPGFRKGKMPRPLFEQRFGVESLYQDALDIILPKAYSEAIDETGIFPVAHPEIDIEKFEKNENLVFTAKVTVKPEVKLGEYKGLAVEKIDTTVTDEDVENELKALQERQAELVVKEDGTVENGDTAVIDFEGFVNGEAFEGGKGENYSLAIGSGTFIPGFEEQLIGLKAGESKDVEVTFPEEYHAEELAGKPATFKVTVHEIKAKELPELNDEFAKDVNEEVATLDELKAKLRTDLEEGKKHEAEHKVRDEVVEKAAANAEIDIPEAMIETELDRMVREFEQRLSQQGMNLELYYQFTGTDADKLKEQMKEDAQKRVRINLVLEAIIKAENIEVAEEEVNAEIEKMAEMYNMPVDAIKQALGSAEALAEDLKVRKAVDFLVDNSKAA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: CENPA_BOVIN
Sequence: MGPRRQKRKPETPRRRPASPAPAAPRPTPSLGTSSRPLARRRHTVLKEIRTLQKTTHLLLRKSPFCRLAREICVQFTRGVDFNWQAQALLALQEAAEAFLVHLFEDAYLLSLHAGRVTLFPKDVQLARRIRGIQEGLG
What is the function of this protein?
Histone H3-like nucleosomal protein that is specifically found in centromeric nucleosomes.  Replaces conventional H3 in the nucleosome core of centromeric chromatin that serves as an assembly site for the inner kinetochore.  The presence of CENPA subtly modifies the nucleosome structure and the way DNA is wrapped around the nucleosome and gives rise to protruding DNA ends that are less well-ordered and rigid compared to nucleosomes containing histone H3.  May serve as an epigenetic mark that propagates centromere identity through replication and cell division.  Required for recruitment and assembly of kinetochore proteins, and as a consequence required for progress through mitosis, chromosome segregation and cytokinesis.
What are the official names of this protein?
Histone H3-like centromeric protein A, Centromere protein A, CENP-A.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Chromosome, centromere. Note=Localizes exclusively in the kinetochore domain of centromeres. Occupies a compact domain at the inner kinetochore plate stretching across 2 thirds of the length of the constriction but encompassing only one third of the constriction width and height.
Protein: NOP53_SCHPO
Sequence: MGIKERNAPSQYKQSSRKNKRAWRKNIDLEDIESGLEQTRDEEIKGGNVEHKPNDALFVIDTLGDDRIAKRSRKKIKPLKVDQILENKSSIEKVHSHLTNNSTESNKKGKIFSRKELNRLQALVYKNKDGLTATSAASELKNTKQPKESYDVWETNPTVTIPVKRPSTLSKLPESLTENNAKVPNVVIADPGMSYNPDAAAWMKLLDTKGSEELKKEQKRISELEEKERIQKKAFEDKGLVSDQDVNHSIDSDDQSEHEQAETPIPSSKNKRKTRSQRNKIRQRREEELRLLEQKKNEELLRTIDKAPAISKKLQQKDKAEKFSNKAVSSSTTEIKLKKKKFGKHRLPNNPLEIKLGDELTSSLRELKPEGNLFADRYLSLQQRAMVPPSLPVLKKSKYRAKIKEKYSHKDFHLQKNSI
What is the function of this protein?
May play a role in ribosome biogenesis.
What are the official names of this protein?
Ribosome biogenesis protein NOP53.
What is the protein family that this protein belongs to?
Belongs to the NOP53 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: SPEA_YERPE
Sequence: MSDDNLISRPLTAGAHVSLRSMQEVAMNDRNASKMLSTYNVAYWGGNYYDVNELGHISVCPDPDIREARVDLAQLVKKMQLEQGQRLPALFCFPQILQHRLRSINAAFKRARESFGYEGGYFLVYPIKVNQHRRVIESLVNSGEPLGLEAGSKAEMMAVLAHAGMTRSVIVCNGYKDREYIRLALIGEKLGHKVYLVIEKMSEIKMVLEEAERLNVVPRLGVRARLASQGSGKWQASGGEKSKFGLSATQVLQLVDMLREANSLESLQLLHFHLGSQLSNIRDISTGVRESARFYVELHKLGVNIQCFDVGGGLGVDYEGTRSQSDCSVNYGLNEYANNVIWGIGDACNEHGLPHPTVITESGRAVTAHHTVLVSNVIGVERNEFCEPQPPEAGAPRALESLWDTWQEMQEPENRRSLREWLHDSQMDLHDVHTQYAHGMLDLTHRAWAEQLYLSICNEIQKQLDPSNRAHRPIIDELQERMADKLYVNFSLFQSMPDAWGIDQLFPVLPLEGLDKPPERRAVLLDITCDSDGTIDHYIDGDGVATTMPMPPYDPENPPLLGFFMVGAYQEILGNMHNLFGDTAAVDVYVFPDGTVEVEQTDEGDTVADMLEYVQLNPEKLLEHFRGQVKETDLDTELQAQFLEEFEAGLYGYTYLEDE
What is the function of this protein?
Catalyzes the biosynthesis of agmatine from arginine.
What are the official names of this protein?
Biosynthetic arginine decarboxylase, ADC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
Protein: DNLJ_GEOSE
Sequence: MDRQQAERRAAELRELLNRYGYEYYVLDRPSVPDAEYDRLMQELIAIEEQYPELKTSDSPTQRIGGPPLEAFRKVAHRVPMMSLANAFGEGDLRDFDRRVRQEVGEAAYVCELKIDGLAVSVRYEDGYFVQGATRGDGTTGEDITENLKTIRSLPLRLKEPVSLEARGEAFMPKASFLRLNEERKARGEELFANPRNAAAGSLRQLDPKVAASRQLDLFVYGLADAEALGIASHSEALDYLQALGFKVNPERRRCANIDEVIAFVSEWHDKRPQLPYEIDGIVIKVDSFAQQRALGATAKSPRWAIAYKFPAEEVVTTLIGIEVNVGRTGVVTPTAILEPVRVAGTTVQRATLHNEDFIREKDIRIGDAVIIKKAGDIIPEVVGVVVDRRDGDETPFAMPTHCPECESELVRLEGEVALRCLNPNCPAQLRERLIHFASRAAMNIEGLGEKVVTQLFNAGLVRDVADLYCLTKEQLVGLERMGEKSAANLLAAIEASKQNSLERLLFGLGIRYVGAKAAQLLAEHFETMERLERATKEELMAVPEIGEKMADAITAFFAQPEATELLQELRAYGVNMAYKGPKRSAEAPADSAFAGKTVVLTGKLASMSRNEAKEQIERLGGRVTGSVSRSTDLVIAGEDAGSKLEKAQQLGIEIWDESRFLQEINRGKR
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: MCP_CALJA
Sequence: MAPPSRRECPFPSRRFPGLLLAALVLLRSSCSDACGPPPTFEAMELTSKPKPYYKVGEQVEYDCKKGYHHFAPFLTHSICDRNHTWLPISDEPCVKKVCHYIPNPLHGEAILANGSYSFGNQLHFICNDGYYLIGKEILYCELKGSDAVWSGRPPICQKIVCKPPPKINNGKHTFSDVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCRDNSLWSDDAPECKVVKCRFPVIENGKQIAGFGKKFYYKATVIFERDKGFHIIGSDTIVCNSNSTWDPPVPKCAKELPPSSTKPPTLSHSVSTSPTTVSPTSSVSGPRPTYKPPVSRYPGYPNPDEGMLNSLDEWAIALIVIAILVGVAIISFGLHRYLQRRKKKGTYLTDETHREVNFTSL
What is the function of this protein?
Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue.  May be involved in the fusion of the spermatozoa with the oocyte during fertilization.  Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells.  T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity (By similarity).
What are the official names of this protein?
Membrane cofactor protein.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, acrosome inner membrane; Single-pass type I membrane protein. Note=Inner acrosomal membrane of spermatozoa.
Protein: Y3701_DICDI
Sequence: MKLLKSLLFLASVLFISSQAEKKVTGELTFYAAGDNCPPSGEIAYPGLHSSAGGLGTYANPITVAASTAWLSAGKKVYVAAYKKYFIMEDSCEECENEWDSNGKYHMDAWIGPSTIHSGTTNCEVALTLSSTQFIIDPLSTYAVDTTAFFNGTTGACLKTPDNCVDQGNECGNTCQIPSSMSCSSAASMFLLSETRFKALNPNLDCTKNIAKGKSVCQSGSCGGP
What are the official names of this protein?
Uncharacterized protein DDB_G0273701/DDB_G0273221.
Protein: RPIA_SINFN
Sequence: MDARQMKIKAAQAALGYVESGMRLGIGTGSTAEEFVRLLAEKVASGFQIQGVPTSERTARLCLELGVPLKSLDELPELDLTIDGADEVDGKLRLIKGGGGALLREKIVASASERMIVIADESKVVDVLGAFKLPIEVNQFGLTTTRLAIEKVAARLGLTGDIGLRASGDGPFMTDGGHLILDASFGRIPDAEALAAGLNAIPGVVEHGLFLGMASLAIIAGPEGARTLTAG
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: SYVC_ENCCU
Sequence: MDSSKEALKERKKMAKDEKKRQKLEKFLAKKTLEIGVSKPRKEYRKEGYDPLQVEGKWYKLWEEQGLFKPVEGGARYVVPIPPPNVTGSLHIGHAMMVSIQDAVCRYKRMCGYEVLYIPGTDHAGIATQNVVSKQLAREGIVVDREGFLKKAWEWKDRHGSRIYEQLKRLGTSVDFGRERFTLDPGMSRAVADAFVKLYEKGLIYREPKIVNWCSRLLTTISDLEVNHEEVMPNTYLQVDGGKYEFGVIYHFKYPITADKGFSGDHLSLPTIEVATTRPETILGDTAVCVNGRDCRFSPEGIKEMLGDVPHGCRIYGVNPLTRDVIPVIFDDYADMSFGTGVVKITPAHDANDFEVSKRHGLPCKVVFDEQNRVVVEGEFKGLKRFEARKAVVSKLRDVGLFVSKKGHPQVIPRCSRSDDVIEPIIKSQWWLNCKEMARKAIEAVEDGRISILPEGAEKQWYKWLGNIRDWCLSRQLWWGHRVPAYKAPSGKWYVGRTKEDAFLKMRSECMGSDCDLSELEQDEDVLDTWFSSGLWPFATLGWPEETEDFLKYYPNTLLETGSDILFFWVARMVMLGLELTGKVPFSQVLLHGIVRDAHGRKMSKSLGNVIDPIFVIDGCSLEKLISTMRSGNLDEREVKRAEAVLRQDFPNGISRCGADALRFALLSYTSGMKDINLDVLRVEGYRRFCNKIWNAHKFVKTMVDELAGKNGNGPVCKDDYGKYIVSSAELPGPSEEGPVEWILRRRNETVEEIRRTLDSFNFMGATQAIHQFFIYDLCDVFIEVVKKSKNEKYIRVLFRVFIDSMKMLHPFMPFITEEVFSNYFNGSISVSPYPETDGSEHESKFSVTLQITRHIRAKAESNGWSKAVVEIAPGGDVNHADLRFIRSLCRKIVELKIISDAEDGPYEKVGGSRVLVRQTE
What are the official names of this protein?
Probable valine--tRNA ligase, cytoplasmic, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSH_SYNJB
Sequence: MSQKGKNKKWRSAGLYALLAIVLISLATTFLGNRPPERLEISYSDLISRVERGEVSKVLVETAPDGRQVAIAEAEINNRATQVQVNLPPLTPEFENTLVANGVELAVRPVQEEGLLGRILSTFFLPVLLLLGLFFLLRRAQNGPGSQALNFGKSRARVQMEPKTQITFNDVAGIDQAKLELAEVVDFLKNSERFTALGAKIPRGVLLVGPPGTGKTLLARAVAGEAGVPFFSISGSEFVEMFVGVGASRVRDLFEQAKQNAPCIVFIDEIDAVGRQRGAGLGGGNDEREQTLNQLLTEMDGFEGNSGIIVIAATNRPDVLDAALLRPGRFDRQVTVDRPDFQGRLEILKVHARGKTLSADVDLEKLARRTPGFTGADLANLLNEAAILAARRNLTEISMDEINDAVDRVLAGPEKKDRLMSERRKELVAYHEAGHALVGSLLPNYDPIQKVTIIPRGQAGGLTWFMPSDDDMGLTTRAHLKNMMTVALGGRVAEEVVYGESEITTGAASDLQQVARIARNMVTRFGMSDRLGNVALGRQYANIFLGREIAAERDFSEETAALIDEEVRRLVNEAYQRATYLIRENRALLDRIARRLVEAETIDGEELQAIIDNSEVVMLPPEEEPEPLTLPMAVNAGA
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein; Stromal side.
Protein: OXR1_XENTR
Sequence: MFSTRRLKKKSQSVDIAASGYNPLSDASAPQASRVPPPIVKAISEEEHHNTTNAQKRHLRRGDLKRGYTIDTGQKKTLEKKDGRRMSFQRPKGTMEYTVETRDSLNSIALKFDTTPNELVQLNKLFSRAVVPGQLLYVPDPDYISSVESSPSLSPISPLSPTSSEAEFEKSTDTERMPYKEITSSPAYSAIRPSRVVSSTSEEEEAFTEKFLKINCKYITDGKGTVNGVLLVTPNNIMFDPHKNDLLVQEKGCEEYGIMCPMEEVTSAAMYKEIVNSKLKDSVSVDVGQLSCMREFCHLKKISPGNLHDIDSQMWDAGNDSASTAPRSTEESLSEDVFTESELSPIREEHLSSDELRQDKSSGASSESVQTINQNITECSLNISDCVSASDDVKDSLEPSGNDSGIVASINDLEKSEASINAGEGVDKDISESSLILTEAIEGHNSNDGILSSNKDKQTGDQNHSREAAFVRNHQHETVQEEAVKQSFGDSETEAEELRKFWKDLTMQQAKQQREDMQHTTQKEIMGKMPTAETHIEGVCSSVAKEKRRHRSHRYLCLRVGKPMRKTFVSQASASMQQYAQRDKLEYWFAVPHERSDHLYSFFIQWSPELYAEEVRESAREPGFVVVKKNEETEGSDCSTNDSAARLWEVVSVAEYHRRIDALNTEELRTLCRRLKITTREDVNSKQATNIKNDQEPESFRPNLSDPSSLLQTDQIEKLTKHLPPRTIGYPWTLVYSTAKHGMSLKTLYRTMLGLDTPVLLVIKDSDAQIFGALASEPFKISDCFYGTGETFLFTFCPDFEVFKWTGDNMFFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHTCKTFGNCILSKKEDFIVQDIEIWAFE
What is the function of this protein?
May be involved in protection from oxidative damage.
What are the official names of this protein?
Oxidation resistance protein 1.
What is the protein family that this protein belongs to?
Belongs to the OXR1 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RS8_MACFA
Sequence: MGISRDNWHKRRKTGGKRKPYHKKRKYELGRPAANTKIGPRRIHTVRVRGGNKKYRALRLDVGNFSWGSECCTRKTRIIDVVYNASNNELVRTKTLVKNCIVLIDSTPYRQWYESHYALPLGRKKGAKLTPEEEEILNKKRSKKIQKKYDERKKNAKISSLLEEQFQQGKLLACIASRPGQCGRADGYVLEGKELEFYLRKIKARKGK
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
40S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS8 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Lipid-anchor. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Protein: TIG_STRMK
Sequence: MQASIESTGNLERRLSFSLPEDRLQSHIVGRLGEIARTTRIKGFRPGKVPAKVIEQRFGAQVRGEALDGLLRETFDAAVREHDLRIVGSPRIDKGDEGEFSFVATVEVVPDFGDIDVSKLTVVRHTAEITDADIDQMIENLQNQRRTWAPVSRGAQDGDLVAVETWSQAGEERLPAEGTEKGSIVLGQGMMFETIEKGLVGLAKGEEKTLDVEFPADWRVPVLAGKTVQVTVKVAEVSEPVVPAVDEAFIKSFGVKGGDVEQFRSDIRANLERELKGALMNRLRREVGEQLIAAYSSVEMPPRLVENEARAMLAQQVEQIRRNGQSVGEIPADAHEGFKEAAAKRVLVGLLVGEVARINDLRLEAKRLNETMRLIASTYEEPEQVIEMYRNDPQLMSGLQNRVMEEQVIDWIAERAQHTEEKLSFQDAIRQ
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: CAPP_STRP8
Sequence: MPLKKLESSNNQAIIAEEVALLKEMLENITRRMIGDDAFTVIESIMVLSEKQDYIELEKVVANISNQEMEVISRYFSILPLLINISEDVDLAYEINYQNNTDTDYLGKLALTIKDLAGKDNGKDILEQVNVVPVLTAHPTQVQRKTILELTTHIHKLLRKYRDAKAGVISLEKWRQELYRYVEMIMQTDIIREKKLQVKNEIKNVMQYYDGSLIQAVTKLTTEYKNLAQKHGLELDNPKPITMGMWIGGDRDGNPFVTAETLCLSATVQSEVILNYYIDKLAALYRTFSLSSTLVQPNSEVERLASLSQDQSIYRGNEPYRRAFHYIQSCLKQTQIQLTNQPAARMSSSVGLNTSACPSPASLENPILAYDSPVDFKADLKAIEQSLLDNGNSALIEGDLREVMQAVDIFGFFLASIDMRQDSSVQEACVAELLKGANIVDDYSSLSETEKCDVLVQQLMEEPRTLSSAAVAKSDLLEKELAIYTTARELKDKLGEEVIKQHIISHTESVSDMFELAIMLKEVGLVDQQRARVQIVPLFETIEDLDNACDIMAAYLSHDIVKSWIATNRNYQEIMLGYSDSNKDGGYLASGWTLYKAQNELTAIGEEHGVKITFFHGRGGTVGRGGGPSYDAITSQPFGSIKDRIRLTEQGEIIENKYGNKDVAYYHLEMLISASINRMVTQMITDSNEIDSFREIMDSIVADSNMIYRKLVFDNPHFYDYFFEASPIKEVSSLNIGSRPAARKTITEITGLRAIPWVFSWSQNRIMFPGWYGVGSAFKRYIDRAQGNLERLQHMYQTWPFFHSLLSNVDMVLSKSNMNIAFQYAQLAESQDVRDVFYEILDEWQLTKNVILAIQDHDDLLEDNPSLKHSLKSRLPYFNVLNYIQIELIKRWRNNQLDENDEKLIHTTINGIATGLRNSG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: CLSA_PECCP
Sequence: MSTFYTVISWLLVFGYWLLIAGVTLRILMKRRAVPSAMAWLLVIYILPLVGIVAYLSFGELHLGKRRAERASKMWPSTAKWLRELKEYRRIFATENSEVASALFQLCERRQGVGGVKGNQLQLMTTFDDTIKALLRDIELARSNIEMVFYIWQPGGLVEQVSSSLIAAARRGVHCRILLDSAGSVQFFRQHHPELMRTAGIEVVEALKVNLFRAFLRRMDLRQHRKIILIDNRIAYTGSMNMVDPRFFKQDAGVGQWIDLMARIEGPVATTLGIIYCCDWEMETGKRLLPPPPDVNVMPFEQESGHTIQVIASGPGYPEEMIHQALLTSVYSARKQLIMTTPYFVPSDDLLHAICTAAQRGVDVSIIVPHKNDSVLVGWASRAFFTELLAAGVKIYQFKDGLLHTKSVLVDGQLSLVGTVNLDMRSLWLNFEITLVIDDAGFGSDLACVQEDYIARSRLLNATQWQNRPYWQRIVERLFYFFSPLL
What is the function of this protein?
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
What are the official names of this protein?
Cardiolipin synthase A, CL synthase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PORTL_BPHA1
Sequence: MGLLKRAARAWKLAGQADSPPAQPARKEPTLTRTFKMARQTRLNNSWTGRSNAGDADHVIYKDHETLRQRAREQSINSGYAKRFYRLLRQNVIGPHGITMRSKALKADGYADDDMRRVIEQEFKKWSKRGNCDVTGRYSFVTFMWLWIDTLARDGEVMVRILRNWPNRWGFALQIIESDLLDTTLNTWLSNGNRVRMGVEIDEWEKPIAYWLKRSHPGDNFERPAEQEYQRIPADELRLTFDPWRPHQSRGFTWTHAGANDLHHVEEYAGAELIAAEQGAKLTGFYEQDAEWVDPPGDEDSDDADQGVIIEEIEAGSARLLPYGVTFKPYDNKHPSTNFAPFTKAAVRRIAGAFGPSYNRLAHDLEGVSFSSLRSGEIDERDFYKCIQQFAISELLEWVGEVWMECSMLKGVLKIPPRAWDRLTPIEWLPRGWDWVDPKKDSDAAKTGIETLTDSVSDIMRRKGRDPDDVYNQISEDIRRFKRLGIPNPYGKALQANGVTHVEPDEEDDDEPNATGTD
What is the function of this protein?
Forms the portal vertex of the capsid.  This portal plays critical roles in head assembly, genome packaging, neck/tail attachment, and genome ejection.  The portal protein multimerizes as a single ring-shaped homododecamer arranged around a central channel.  Binds to the terminase subunits to form the packaging machine.
What are the official names of this protein?
Probable portal protein.
What is the protein family that this protein belongs to?
Belongs to the siphoviridae portal protein family.
What are the subcellular locations of this protein?
Virion.
Protein: POB1_SCHPO
Sequence: MASQRFVIALHSFPGKSSDELPLVEGRKYLLIKMDEEFGDGWWEGEDEQGNRGIFPASHVELISDERSDSSDSRRGKEDFSISTAEVTRSSLSSSRSTSSRSDKDSEKLYSNNSLSSSHSSILNGPLDSLSKPSVPSNFNSMFPSSKQEGPSPLLDNQPSSDLSNFNTIDADYNNASASTSAPATSASLKKVLSAEDSVRETITDIETALQNMSTSASRTPNDSSPLPYIENRPASSLAVSEKIQNVPNWSTEEVVEWLMNAGLGSVAPNFAENEITGEILLGLDSNVLKELNITSFGKRFEVLRKIQQLKDSYEQSLYEEYPQFAEPISVSQSSDSSSSIPKKSNDEAGGSPSKSSPTRPGFNDYVNRPTSVMPSLSNMIVSPDLDSSPSTDWNQYVIPPLATPSSRNSKSTQSAVPENVSRFDSNEPSATSPILKRSSPTDSISQNSGLPSRLTEPISSPSTSSIDVDKEGTSFPGLPYHSSKGNLYAPQPSSNVPTKFTGGASESSSVPPRPIPSAMKGKAPASAISIEALEELDPPKITTIDGESPSSISSRLPSSNLEQGSSSSVTKSPESMPDPSAKASSPVTSKGVSINEKSAVNNYATPLSKPQPKDTKGSKLGNTFVAPSPAASLPASPPVGTELKTRPTLRSVASSPLNKEPIGKRKSKRDIFGRQKVLPTGISEGLSNIPAKEAIKTADCHGWMRKRSDRYGVWKSRYFVLKGTRLSYYHSLNDASEKGLIDMTSHRVTKTDDIVLSGGKTAIKLIPPAPGAAKAAVMFTPPKVHYFTCENNEELHRWSSAFLKATVERDMSVPVLTTSRMPTISLSKAKELRTRPPSLLIDDENEANLTSSIGLKKNAKQKNKKSSKQK
What is the function of this protein?
Has a role in cell elongation and separation.
What are the official names of this protein?
Protein pob1, BOI protein homolog.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein. Note=Membrane-associated at the cell tips during interphase.
Protein: AOX_BLUGR
Sequence: MYLSRLPPRSIPCRSINQISRVVARSSKSRLEFVGSYQNSLTTNQTRCLRPFSSTSRSQLRDYFPEADHEHIKKTEAAWPHPNYPKEQMLTNISYAHRTPKDFSDRIALYLVRFLRFSTDLATGYKHDPVTITENGEKVLKKPYRMSERKWLIRMVFLESVAGVPGMVAGMLRHLHSLRRLKRDNGWIETLLEEAYNERMHLLTFLKMAKPGWFMKFMIIGAQGVFFNSMFLSYLISPRTCHRFVAYLEEEAVLTYSTAIQDIEAGLLPKWTSPEFRIPDLAVQYWKIPEGNRTMRDLLLYIRADEAKHREVNHTLGNLDQNEDPNPFVSEYRDKAAPHPSKGIEHIRPTGWERNEII
What is the function of this protein?
Catalyzes cyanide-resistant oxygen consumption.  May increase respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures (By similarity).
What are the official names of this protein?
Alternative oxidase, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the alternative oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein; Matrix side.
Protein: THIE_DICT6
Sequence: MNKGEKLSLFKDYNLYCLTCEDYSLGRRNIDVVREILNAGVRIIQYREKKKTMREKYQEAKKIRELTAQYNALLIINDHLDLAKIVEADGVHIGQEDYPIEVAKEYLGDEFIIGLTTHTKTQVIEAFQKGADYIGLGPIFPSYTKEKPHPPIGLEIIEWAVNHVHIPIVAIGGIKESNIYEVLKHGAKCIAMVTEIVSSQDIYEKTKNIIRILEGYKNGKNLA
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: EBNA6_EBVA8
Sequence: MESFEGEGDSIQSPDNARGDDVQNTGEHIQDPGPGPSTGGASEGLVQNEPDSRDQQSRGQRRGDENRGWMQRIRRRRRRRAALSGHLLDMEDNVPPWFPPHDITPYVARNIRDAACQAVKHSHLQALSNLILDSGLDTQHLLCFVMAARQRLQDIRRGPLVVEGGVGWRHWLLTSPSRSWSMGYRTATLRTLTPVPNRVGADSIMLTATFGCQNGALAINTFSATVWIPPPAGPREQERYAREAEVRFLRGKWQRRFRRIFDLIELCGSLHHVWQNMLQTEENLLDFVRFMGVMSSCNSSSVNYWFHKTIGNFKPYYPWNAPPNENPYHARRGIKEQVIQKAFLKAQRQGLSMLATGGGPRGDATSETSSDEDTGRQGSDVELESSDDELPYIDPNMEPVQQRPVMFVSRVPVRKPRTLPWPTPKTHPVKRTIVKTSYRSDEAEEAQSTPERPGPSKQPSEPVEPAHTTPAGRSTVILHEPPREPEAVSFKPPPPPSRRRRGACVVYDDDIIEVIDVETTEEETTSMQRQPPLGQQPPPPVISTGSAMSSSHTDPSVTQPSKPHRKPQDGFQRSGRRQKRAMPPPVSPSDAGPPSTRPRVMAPPSTGPRVMATPSTGPRDMAPPSTGPRDMAPPSTGPRDMAPPSTGPRDMAPTVVHMFTRERLLTQSTGPAPRSFWEMRAGRDAPKIQQEPSSQQQPATQSTPPCQSWVPSVYVLPAVDAGNAQPLQISHLSSMSPTQPISHEEQPRYEDPDTPLDLSLHPDTATLPPTQDLYPGREDLQATQAPYPGYEEPRPPQAPFVGDYGFVQIPSAQWEPHPSQGTYQGHIDPQLPAALDLGPEQPRFPQDPYVYSGGQLSSCPGYAGPWPSRPQHPRYRHTLALWPREPRHGHSQGPWKPWSAHLPPQWDGSAGHGQDQVSQFPHLHSETGPPRLQLSSVPQVLYPQPLVSSSAPSWSSPQPRAPIRPIPTRFPPPPMPLQDSMAVGCDSSGTACPSMPFASDYSQGAFTPLDINAPTPKSPRVEESSHGPARCSQATSEAQEILSDNSEISVFPKDAKQTDYDASTESELD
What is the function of this protein?
Plays an essential role for the activation and immortalization of human B-cells.  Represses transcription of viral promoters TP1 and Cp through interaction with host RBPJ, and inhibits EBNA2-mediated activation of these promoters.  Targets host chromatin through interactions with host transcription factors, especially RBPJ and IRF4.  Alternatively, EBNA6 also regulates the transcription of the EBV oncogene LMP1 in a cell cycle-dependent manner.  Modulates the activity of several host proteins involved in cell cycle regulation including host cyclin A, MYC, RB, p21 and p27 mainly through binding to the host SCF(SKP2) complex.  Inhibits the promoter of host H2AX and targets H2AX to proteasomal degradation in order to promote latency and cell proliferation.  Upregulates host PIM1 expression and stabilization.  Potentiates PIM1 to promote cell proliferation by inhibiting the growth suppressive properties of p21.
What are the official names of this protein?
Epstein-Barr nuclear antigen 6, EBNA-6, EBV nuclear antigen 6, Epstein-Barr nuclear antigen 3C, EBNA-3C, EBV nuclear antigen 3C, Epstein-Barr nuclear antigen 4B, EBNA-4B, EBV nuclear antigen 4B.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae EBNA-6 family.
What are the subcellular locations of this protein?
Host nucleus. Host nucleus matrix. Note=Associated with the nuclear matrix.
Protein: PSUG_LEGPH
Sequence: MFHDLLEFNEEVLDAINDKNPIVALESTIISHGMPYPDNLTTAIEVENIIRRQGAIPATIAMHQGKIRVGLTQEVMEHLALQKEVIKASRRDISFVLSRKVTASTTVAATMFCAHMAKLPLFVTGGIGGVHQDVTMSFDISADLIELSNTPVTVVCSGAKSILDLPKTLEVLETFGVPVIGYATDEFPAFYSRSSGIPVPQRLNSAEEVANLMSIQQKLNMKNGIVVANPIPVSAELSDEEISPYIKQAHDEAKHMSGKSLTPFLLKRIAELTAGKSLEANIELIKNNAFLGAEIAIAYQKKLFSKKT
What is the function of this protein?
Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil.  Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
What are the official names of this protein?
Pseudouridine-5'-phosphate glycosidase, PsiMP glycosidase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine-5'-phosphate glycosidase family.
Protein: TRAR_AGRVI
Sequence: MQHWLDKLTDLTAIEGDGCILKTGLADVADHFGFTGYAYLHIQHKHIIAVTNYHHDWRSLYFDKKFDALDPVVKRARSRKQVFAWSGEQERPKLSEEERAFYAQAADFGIRSGITIPIRTANGSMSMFTLASERTAIPLDREIDAVAAAAAVGQLHARISFLRITPTAEDAAWLDPKEATYLRWIAVGKTMEEIADVEEVKYNSVRVKLREAMKRFDVRSKAHLTALAIKRKLI
What is the function of this protein?
Positive regulation of conjugal transfer of Ti plasmids.
What are the official names of this protein?
Transcriptional activator protein TraR.
What is the protein family that this protein belongs to?
Belongs to the autoinducer-regulated transcriptional regulatory protein family.