PharMolix/UniProtQA huggingface dataset:
Protein: MOAA_SACS2
Sequence: MIDRFGRPLEDLRITLTHACNFECFFCHMEGEEGDNYLLSKEDILLVAKVARKFGINSVKLTGGEPTLRRDLVEIVRGLKQLGYEDVSMTTNGFLLKDLAHKLKLAGLDRINISLHAVSRDTFKKITGVDAFDRVIEGIKSAIDVGLVPVKLNFVVNRRNREEAFKFIELSQNLGVNEIHLIELHPVGLGKLAFKEHDDLREIEEYIEKISIKKLIRKKHFRPRYVLPSGLIVEVVKPYANPIFCAGCNRIRLSVDGKLKTCLYREDNVIDVLDILKGEYSEDVKEELLGRAFMIAIAIREPNFKYKI
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
Probable GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: TMT1_YEAS7
Sequence: MSTFSASDFNSERYSSSRPSYPSDFYKMIDEYHDGERKLLVDVGCGPGTATLQMAQELKPFEQIIGSDLSATMIKTAEVIKEGSPDTYKNVSFKISSSDDFKFLGADSVDKQKIDMITAVECAHWFDFEKFQRSAYANLRKDGTIAIWGYADPIFPDYPEFDDLMIEVPYGKQGLGPYWEQPGRSRLRNMLKDSHLDPELFHDIQVSYFCAEDVRDKVKLHQHTKKPLLIRKQVTLMEFADYVRTWSAYHQWKQDPKNKDKEDVADWFIKESLRRRPELSTNTKIEVVWNTFYKLGKRV
What is the function of this protein?
Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate and 3-isopropylmalate at high affinity and of other molecules like cis-aconitate, isocitrate, and citrate at lower velocities and affinities.  The function of trans-aconitate methylation appears to be in reducing the toxicity of this spontaneous breakdown product of cis-aconitate.  The role of 3-isopropylmalate methylation is unclear but may represent a metabolic branch at 3-isopropylmalate, where some of the material is taken in the pathway leading to leucine and some is taken in a pathway to the 3-isopropylmalate methyl ester, a molecule that provides a signal to switch from vegetative to invasive growth in response to amino acid starvation (By similarity).
What are the official names of this protein?
Trans-aconitate 3-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Tam family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANF_LITCT
Sequence: MGTSFVGYLTFVLLLLALTKVRGGPAYNSPLSSDLSDLKGLLERLEDRLPVEEVETPVQDIFAPNYDSADSSNSAPSLTVEAARPGADMMYNRGSWTQQEKSSPLRNKLRELLNAPRSMRRSSDCFGSRIDRIGAQSGMGCGRRF
What is the function of this protein?
Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation.  Has a cGMP-stimulating activity (By similarity).
What are the official names of this protein?
Natriuretic peptides A.
What is the protein family that this protein belongs to?
Belongs to the natriuretic peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: DNAJ_ECO55
Sequence: MAKQDYYEILGVSKTAEEREIKKAYKRLAMKYHPDRNQGDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQGGMGGGGFGGGADFSDIFGDVFGDIFGGGRGRQRAARGADLRYNMELTLEEAVRGVTKEIRIPTLEECDVCHGSGAKPGTQPQTCPTCHGSGQVQMRQGFFAVQQTCPHCQGRGTLIKDPCNKCHGHGRVERSKTLSVKIPAGVDTGDRIRLAGEGEAGEHGAPAGDLYVQVQVKQHPIFEREGNNLYCEVPINFAMAALGGEIEVPTLDGRVKLKVPGETQTGKLFRMRGKGVKSVRGGAQGDLLCRVVVETPVGLNEKQKQLLQELQESFGGPTGEHNSPRSKSFFDGVKKFFDDLTR
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROA_GRABC
Sequence: MSENHSEGASRPVISRRPAAGLRADHPVHVPGDKSISHRALMIGALAVGETRISGLLEGEDVLRTAAAMRALGAEVVRDAPGSWRVAGRGIGGLTEPADVLDMGNSGTAARLLTGVLASHDLFAVMTGDASLRKRPMRRVTDPLAACGAGFHTRSGGRLPMAVRGTGEALPLHYRLPVASAQVKSAILLAGLNARGETVVEEPHATRDHSENMLRHFGATVQVEPTGDGAGRIVRLQGQPELRAADIVVPADPSSAAFPLVAALLVPGSEITLAGVGLNPLRTGLFDTLVEMGAALTIANRRIEGGEPVGDITVRASTLHGVEVPPERAPSMIDEFPILSVAAAVASGTTRMRGLAELRVKESDRLAATAALLSVNGVQVEIEGDDLIVIGCGGPPPGGGLVTTYMDHRLAMSALVLGLTTQAPVTADDAAFIDTSFPGFATLMTGLGADFSCA
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_RENSM
Sequence: MAKAEIRKPKPKSNPLKAADITVIDYKDVALLRKFISDRGKIRARRVTGVTVQEQRKIAQAIKNAREVALLPYSGAGRG
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: RLMH_ACIB3
Sequence: MKIRILTIGQKMPAWVLTGFEDYFKRIQPFVQTQVIELPMAKRGKNDSEADILKYCQIEGESILNALKPNETLIALEVGGRELSTEKLADTMKQWMLEGNDVALAIGGPDGLSDQVRKAAAWHWSLSKLTMPHPLVRILLIEQLYRAMSINHNHPYHRA
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2629_BACP2
Sequence: MAKMTSRQLANELKSRLTNDNWSHQFDREKDTLRIEDKQTGKGITLELPPIIAKWEVKPDETLDEIVYYVKEALSAMKGEAQHISGKEKQIYPVIRSTSFPEASSDGIPLVFDEHTAETRIYYALDLGSTYRLIDEKMLQKENWTKERIRETASFNVRSLETVVKMDEVAGNRFYFFRANDGYDASRLLNESILQEYAQKIEGQMAISVPHQDVFIIADVCNESGYDILGQMSMSFFASGTVPITALSFLYDEGKLEPIFILAKSRPKQQ
What are the official names of this protein?
UPF0354 protein BPUM_2629.
What is the protein family that this protein belongs to?
Belongs to the UPF0354 family.
Protein: KV6A9_MOUSE
Sequence: QIVLTQSPAIMSASPGQKVTMTCSASSSVSYMHWYQQKSGTSPKRWIYDTSKLASGXPARFSGSGSATSYSLTITSMQAEDAATYYCQQWSSNPLTFGAGTKLELKR
What is the function of this protein?
Anti-2-phenyl oxazolone (PHOX) Antibody.
What are the official names of this protein?
Ig kappa chain V-VI region NQ6-8.3.1.
Protein: F228B_MOUSE
Sequence: MTTMKNRSQDDMVTGTLPKLKSSKEWLEPQSLSFMEALAKEDTDAAVQSILYRENYIMKELDKYLHHQDFLNTRRKEMLYKKWVERVADPLQKKIIEKVHSHKNIKKRRRQELDNFLKHSNKKGNAFIEHYDPKEYDPFYMSKEDPNFLKVIMPPFRDPLKKAQYDQDDEKRTLLQCETGKIYTMKEFKEIEKAQLHSRFPSISNSRQSMTPNGWLKVPMSYIESEFCKKSR
What are the official names of this protein?
Protein FAM228B.
What is the protein family that this protein belongs to?
Belongs to the FAM228 family.
Protein: RAS1_DROWI
Sequence: MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLLVFAVNSAKSFEDIGTYREQIKRVKDAEEVPMVLVGNKCDLPSWNVQNEQAREVAKQYGIPYIETSAKTRMGVDDAFYTLVREIRKDKDNKGRKGRKLNKPNRRFKCKML
What is the function of this protein?
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.  Plays a role in eye development by regulating cell growth, survival of postmitotic ommatidial cells and differentiation of photoreceptor cells.  During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis.
What are the official names of this protein?
Ras-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: CCA_YERP3
Sequence: MNIYLVGGAVRDSLLNLPVTEQDWVVVGATPEQLLKLGYQQVGKDFPVFLHPVSHEEYALARTERKSGQGYTGFTCYAAPDVTLEDDLLRRDLTVNAIARSADGEFIDPYHGKQDLENRVLRHVSDAFGEDPLRVLRVARFAARFAYLGFTIAPETMSLMSNMAQSGELSALTPERVWKETEKALKTQSPHVYFQVLRDCGALAVLFPEIERLFGVPAPEKWHPEIDTGIHTLMTLAIAAQLSPEVDIRFAALCHDLGKGLTPKEHWPHHHGHGPAGVKLVEQLCQRLRIPNPVRDLAKLVAEYHDLIHTVNKLRPETLLKLFNAIDVWRKPERLEQMIMTSEADARGRTGFENNPYPQGDYLRAAFQIANGVSIQEVVASGLQGLAIRDELQRRRQQALAEWKQTQETPLI
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: PCDBD_HUMAN
Sequence: MEASGKLICRQRQVLFSFLLLGLSLAGAAEPRSYSVVEETEGSSFVTNLAKDLGLEQREFSRRGVRVVSRGNKLHLQLNQETADLLLNEKLDREDLCGHTEPCVLRFQVLLESPFEFFQAELQVIDINDHSPVFLDKQMLVKVSESSPPGTTFPLKNAEDLDVGQNNIENYIISPNSYFRVLTRKRSDGRKYPELVLDKALDREEEAELRLTLTALDGGSPPRSGTAQVYIEVLDVNDNAPEFEQPFYRVQISEDSPVGFLVVKVSATDVDTGVNGEISYSLFQASEEIGKTFKINPLTGEIELKKQLDFEKLQSYEVNIEARDAGTFSGKCTVLIQVIDVNDHAPEVTMSAFTSPIPENAPETVVALFSVSDLDSGENGKISCSIQEDLPFLLKSAENFYTLLTERPLDRESRAEYNITITVTDLGTPMLITQLNMTVLIADVNDNAPAFTQTSYTLFVRENNSPALHIRSVSATDRDSGTNAQVTYSLLPPQDPHLPLTSLVSINADNGHLFALRSLDYEALQGFQFRVGASDHGSPALSSEALVRVVVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATELGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSATATLHVLLVDGFSQPYLPLPEAAPTQAQADLLTVYLVVALASVSSLFLFSVLLFVAVRLCRRSRAASVGRCLVPEGPLPGHLVDMSGTRTLSQSYQYEVCLAGGSGTNEFKFLKPIIPNFPPQCPGKEIQGNSTFPNNFGFNIQ
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.  May be involved in the establishment and maintenance of specific neuronal connections in the brain.
What are the official names of this protein?
Protocadherin beta-13, PCDH-beta-13.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: AGRG6_MOUSE
Sequence: MMFDTLGKRCCPWRLKPSALLFLFVLCVTCVPLSVCGCGSCRLVLSNPSGTFTSPCYPNDYPNTQSCSWTLRAPAGYIIQITFNDFDIEEAPNCIYDSLSLDNGESQTKFCGATAKGLSFNSSVNEMHVSFSSDFSIQKKGFNASYIRVAVSLRNQKVILPQTLDAYQVSVAKSISIPELKAFTLCFEASKVGNEGGDWTAFSYSDESLTQLLSLEKASNGYFLSISGSRCLLNNALPVKDKEDIFTENLEQLCLVWNNSWGSIGINFKKNYETVPCDSTISAVVPGDGTLLLGSDRDEVASLRGSIYNFRLWNFTMDLKALSNLSCSVSGNVIDWHNDFWSISTQALKAEGNLSCGSYLIQLPAAELTNCSELGTLCQDGIMYRISVVIHNDFNHPEVKVQTKVAEWLNSTFQNWNYTVYVVNISFHQKVGEDRMKVKRDIMDDDKRLVLWALLVYNATNNVSLNEEKIKQKLMTNNASLEDGLRLCEVDVNQLGMCSALEDPDGFSWPATLPSVYKQPCPNKPGFFMTRACLSNGTSTFWGPVDTSNCSRQSNEVANEILNQTGDGQNLTSANINSIVEKVKRIVNKEENIDITLGSTLMNIFSNILSSSDSDLLESSTEALKTIDELAFKIDLNSTPHVNIETQNLALGVSSLIPGTNAPSNFSIGLPSNNESYFQMDFGNGQTDPLASVILPPNLLENLSPEDSVLVRRAQFTFFNKTGLFQDVGSQRKVLVSYVMACSIGNITIQNLKDPVQIKIKHTRTQEVHHPICAFWDMNKNKSFGGWNTSGCVAHSDLDAGETICLCSHFTHFGVLMDLPRSASQIDGRNTKVLTFITYIGCGISAIFSAATLLTYVAFEKLRRDYPSKILMNLSSALLFLNLIFLLDGWVTSFGVAGLCTAVAALLHFFLLATFTWMGLEAIHMYIALVKVFNTYIHRYILKFCIIGWGLPALVVSIILVSRRQNEVYGKESYGKDQDDEFCWIQDPVVFYVSCAGYFGVMFFLNVAMFIVVMVQICGRNGKRSNRTLREEVLRNLRSVVSLTFLLGMTWGFAFFAWGPLNIPFMYLFSIFNSLQGLFIFIFHCAMKENVQKQWRRHLCCGRFRLADNSDWSKTATNIIKKSSDNLGKSLSSSSIGSNSTYLTSKSKSSSTTYFKRNSHSDNFS
What is the function of this protein?
Plays an important role in heart developmention (PubMed:24082093).  Necessary and sufficient for axon sorting by Schwann cells independently of the ADGRG6-CTF (PubMed:25695270).
What are the official names of this protein?
Adhesion G-protein coupled receptor G6, Developmentally regulated G-protein-coupled receptor, G-protein coupled receptor 126.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRPF_CAMJ8
Sequence: MLKLKICGIKDEKNAKDLAFLNIDFFGFIFAKSPRRVSLEQARNLSAIFHEKDKKVVGVFVDENLEQILRCIKEAKLDGIQIYRTITKEEFEILKVQNVFVWQVISVENSLDLKSEIFANLVLFDAKGILKGGNGISFDWTLLGSYTKDFILAGGIGLDNVHKAVQTGAKILDLNSKLEDEKGLKDINKIKQILKELKK
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: LTACT_BPT4
Sequence: MTQFSLNDIRPVDETGLSEKELSIKKEKDEIAKLLDRQENGFIIEKMVEEFGMSYLEATTAFLEENSIPETQFAKFIPSGIIEKIQSEAIDENLLRPSVVRCEKTNTLDFLL
What is the function of this protein?
Activates transcription at late promoters when the sliding clamp is present (PubMed:33602900).  Binds to both the host RNA polymerase (RNAP) and the upstream dsDNA (PubMed:33602900, PubMed:8106327).
What are the official names of this protein?
Late transcription coactivator, Gene product 33, gp33, RNA polymerase-associated protein Gp33.
What is the protein family that this protein belongs to?
Belongs to the Tevenvirinae late transcription coactivator family.
Protein: LST1_HUMAN
Sequence: MLSRNDDICIYGGLGLGGLLLLAVVLLSACLCWLHRRVKRLERSWAQGSSEQELHYASLQRLPVPSSEGPDLRGRDKRGTKEDPRADYACIAENKPT
What is the function of this protein?
Possible role in modulating immune responses.  Induces morphological changes including production of filopodia and microspikes when overexpressed in a variety of cell types and may be involved in dendritic cell maturation.  Isoform 1 and isoform 2 have an inhibitory effect on lymphocyte proliferation.
What are the official names of this protein?
Leukocyte-specific transcript 1 protein, Protein B144.
What is the protein family that this protein belongs to?
Belongs to the LST1 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Golgi apparatus membrane; Single-pass membrane protein. Endomembrane system; Single-pass membrane protein. Note=Also detected in a perinuclear region corresponding to the localization of the Golgi apparatus and throughout the cytoplasm.
Protein: RLME_AROAE
Sequence: MKRTKTSKAWMQEHVNDPYVQRAKSEGYRSRAAFKLIELDDRDRLMRSGMVVVDLGAAPGSWSQVALRRVGREGRVFALDLLPLDPLGGVEFIQGDFQEEPVLAELESRLGGLPVDVVLSDMAPNMSGIDTTDQARSIYLGELALEFAGHHLKPGGGFVVKVFQGQGFMEYRNEAAKHFHALHVRKPKASRDRSAEVYLVGVGYRGS
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EF2_CRYPV
Sequence: MVNFTVEQIREIMGKPHNIRNMSVIAHVDHGKSTLTDSLVCKAGIIASKAAGDARFTDTRADEQERCITIKSTGISLFFEHDLEDGKGRQPFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDAVDGVCIQTETVLRQALNERIRPVLHVNKVDRALLELQWEAEDIYQNFTRVIENVNVIISTYSDELMGDVQVFPEKGTVSFGSGLHGWAFTIEKFARIYAKKFGVEKSKMMQRLWGDNFFNPETKKFTKTQEPGSKRAFCQFIMEPICQLFSSIMNGDKAKYEKMLVNLGVELKGDDKALVDKPLLKKVMQLWLSAGDTLLEMIVTHLPSPAAAQKYRVENLYEGPQDDETAKGIRNCDPDAPLCMFVSKMVPTSDKGRFYAFGRVFSGTVATGQKVRIQGPRYVPGGKEDLNIKNIQRTVLMMGRYVEQIPDVPAGNTVGLVGIDQYLLKSGTITTSETAHNIASMKYSVSPVVRVAVRPKDNKELPKLVEGLKKLSKSDPLVVCSKEETGEHIIAGCGELHVEICLQDLQQEYAQIEIVASDPIVSYRETVVNLSNQTCLSKSPNKHNRLYMTAEPLPDGLTDDIEEGKVSPRDDPKERSNLLHDKYGFDKNAAMKIWCFGPETTGPNIMVDVTTGIQYLTEIKDHCNSAFQWATKEGILCEEDMRGIRFNLLDVTLHADAIHRGAGQITPTCRRVMYAAALTASPRLLEPMFLVEISAPQEVVGGIYATLNQRRGHVFHEEPKSGTPQVEIKAYLPVADSFKFTTVLRAATSGKAFPQCVFDHWELINGDPLEKGSKTEELVKAIRRRKNIKEEIPALDNYLDKL
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).
What are the official names of this protein?
Elongation factor 2, EF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RT25_ASPOR
Sequence: MGKYNLTALRVRQTALRQKEAGKTHQIPKWIDVVRDIPPAQVLVRNQQQQHQLVRQRLKTLPGASKPQVVFEVQEKRVKPKKASRMFLPTEIKYEEDLLRKEFFRDHPWELARPRVVLESTGKDYENYDWSRLQQPGKRLDGESVVQRQLWLLNNVPDMTKSTAYDIARREFYRLRLQEDIERRVAAEEAEATGATFGPTRLEIGMELENQEYERWKVWAKSEAQVQEQRAAAFTGAPEIPSTEDSLGLEEGVEEKQPQQA
What are the official names of this protein?
37S ribosomal protein S25, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mS23 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: KPC2_DROME
Sequence: MAAAAVATPGATVLPPSVPSAAPGAKAPAAGAGKGPGNLLEITGEANIVNYMKNRLRKGAMKRKGLEMVNGHRFGVRFFKNPTYCGHCKDFIWGFGKQGFQCEECRFNIHQKCCKFVVFKCPGKDTDFDADCAKVKHGWISTTYTTPTFCDECGLLLHGVAHQGVKCENCNLNVHHACQETVPPMCGADISEVRGKLLLYVELKGNNLKVDIKEAANLIPMDTNGFSDPYIAVQMHPDRSGRTKKKTKTIQKNLNPVFNETFTFELQPQDRDKRLLIEVWDWDRTSRNDFMGSFSFSLEELQKEPVDGWYKFLSQVEGEHYNIPCVDAFNDIARLRDEVRHDRRPNEKRRMDNKDMPHNMSKRDMIRAADFNFVKVIGKGSFGKVLLAERRGTDELYAVKVLRKDVIIQTDDMELPMNEKKILALSGRPPFLVSMHSCFQTMDRLFFVMEYCKGGDLMYHMQQYGRFKESVAIFYAVEVAIALFFLHERDIIYRDLKLDNILLDGEGHVKLVDFGLSKEGVTERQTTRTFCGTPNYMAPEIVSYDPYSIAADWWSFGVLLFEFMAGQAPFEGDDETTVFRNIKDKKAVFPKHFSVEAMDIITSFLTKKPNNRLGAGRYARQEITTHPFFRNVDWDKAEACEMEPPIKPMIKHRKDISNFDDAFTKEKTDLTPTDKLFMMNLDQNDFIGFSFMNPEFITII
What is the function of this protein?
This is a calcium-activated, phospholipid-dependent, serine- and threonine-specific enzyme.  This isozyme is a negative regulator of the visual transduction cascade and has been shown to be required for photoreceptor cell inactivation and light adaptation.  Negative regulation is dependent on interaction with scaffolding protein inaD.  Acts in a hh-signaling pathway which regulates the Duox-dependent gut immune response to bacterial uracil; required for the activation of Cad99C and consequently Cad99C-dependent endosome formation, which is essential for the Duox-dependent production of reactive oxygen species (ROS) in response to intestinal bacterial infection (PubMed:25639794).
What are the official names of this protein?
Protein kinase C, eye isozyme, Eye-PKC, Inactivation no after-potential C protein, Protein INAC, Photoreceptor-specific PKC, dPKC53E(EY).
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
Protein: Y5863_DICDI
Sequence: MTLLKTISNLGTNNSLKAQSNIQMQPNELLLNNKNSFGQNETKNFDVNGFLATMGQAIEIASFAARFFL
What are the official names of this protein?
Putative uncharacterized protein DDB_G0285863.
Protein: TRPF_PETMO
Sequence: MIRIKVCGITNIEDAINISKAGVDALGFILAESPRKVELSKVLEISKELPPFVSRVAVVVNPVKEEIEKIERSKVFDYVQFHGSEDVNIIKNCKLKTIKAIKIENKSSLEEISKYNDFVDYFLFDTKIGEKIGGTGHTFNWEILKEANIKKPFILAGGLSPENIVEAIKTIRPNAVDLNSKVELYPGKKDIRLIKETIDRINSIKIK
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: H1_PARAN
Sequence: PGSPQKRAASPRKSPRKSPKKSPRKASASPRRKAKRARASTHPPVLEMVQAAITAMKERKGSSAAKIKSYMAANYRVDMNVLAPHVRRALRNGVASGALKQVTGTGASGRFRVGAVAKPKKAKKTSAAAKAKKAKAAAAKKARKAKAAAKRKAALAKKKAAAAKRKAAAKAKKAKKPKKKAAKKAKKPAKKSPKKAKKPAKKSPKKKKAKRSPKKAKKAAGKRKPAAKKARRSPRKAGKRRSPKKARK
What is the function of this protein?
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.
What are the official names of this protein?
Histone H1, gonadal.
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: GLYA_LEGPL
Sequence: MFDESYTIKNFDDVLFKAISDEKRRQEEHIELIASENYVSPRVLEAQGSVLTNKYAEGYPGKRYYGGCEFVDVAEELAISRAKLLFGAHYVNVQPHSGSQANAAVMMALLSPGDTFMGMALPHGGHLTHGSKVNFSGKLYHSVEYGVDNNTGLIDYDALEKLALQHKPKLIIAGFSAYSRILDWARFREIADKVGAYLMADIAHVAGLVAVGLYPSPVPYADVVTTTTHKTLRGPRGGLILCKENEEIEKKLNSAVFPGMQGGPLMHVIAAKAVAFAEALLPEFKTYQQQVLANARTMCSVLQSRGYDIVSGGTDNHLLLVDLINKGITGKEADAALGRANITVNKNSVPNDPRSPFVTSGLRLGTPAATTRGFKEREITLLSNWVADVLDNVHDETNISRVKTQVLLLCREFPVYA
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_DESHD
Sequence: MLAKRIIPCLDVHEGRVVKGTNFVNLRDAGDPVELAALYDREGADELVFLDISASAEGRETMVEVVRRTAEQVFIPFTIGGGLRRVEDIRKMLRAGADKVSLNTSAVQTPGLIEEGAHAFGSQCIVVAIDARQTRPGAWEVYIHGGRTPTGKDVLQWAEEVERLGAGEILLTSMNRDGTKNGYDLELTRAVSRAVSLPVIASGGVGTLEHLAEGLTIGEADAVLAASIFHYQEYSIGEAKAYLEERGIPVRKG
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSI7_PSEAE
Sequence: MLKKLSPIFSNITGVVRYQDLAYVASVSDEIQEQNIAHSYVTEWDCGTWCVAGEDDDMLPWEIVSATVVHEPVEQALFLGARGQVFCMGSGDIHEEQLPDGDDAIGGRGNMRGVACIDGVAYACGMDRQVYRRFDENDWRAIDTGARPPAGSEAVVGFEAIGGFGAREIYAVGWDGEIWQYDGKRWQPRESPTNLILTAICCAEDGSVYACGQAGTLLRGRNDHWEIIAQDDVDEDLWSLAWFDGALYVSSATAVYTLVGGHLKEVDFGDEQPQRCFHLSAADGVLWSIAAKDIFSFDGQQWTRID
What is the function of this protein?
Immunity protein that plays a role in preventing early activation of toxin Tse7.  Protects thereby cells from Tse7 DNase activity.
What are the official names of this protein?
Immune protein Tsi7.
Protein: CBID_BURA4
Sequence: MRDETPERAAPLRFGYTTGSCATATSLAAARLLVAGHADDAVEIVLPKGQRVMMRLEFCRITADGAEAGTIKDAGDDPDVTHGALVFARVALSAAPGVRFHAGPGVGTVTRAGLTLPVGEPAINPVPRQMMTTHLDALAAEYGYAGGFDVTIGVEGGEALALKTMNPRLGIVGGLSILGTTGIVRPFSCSAYIASIHQGIDVARANGIAHIAACTGNTSEDAMRAHYGLPDMALIEMGDFAGAVLKHLRRAPVSRLSMCGGFGKLSKLAAGHLDLHSRHSSIDLPLLAQWAAEAGANDALQAAMRAANTSQEALKLALADGVPLGDLVCAHALRVARDIVPASVAVEMFAIDRQGRFVGSAR
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.