PharMolix/UniProtQA huggingface dataset:
Protein: NCBP2_BOVIN
Sequence: MSGGLLKALRSDSYVELSQYRDQHFRGDNEEQEKLLKKSCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFKEGRQYGRGRSGGQVRDEYRQDYDAGRGGYGKLAQNQ
What is the function of this protein?
Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export.  The CBC complex is involved in mRNA export from the nucleus via its interaction with ALYREF/THOC4/ALY, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore.  The CBC complex is also involved in mediating U snRNA and intronless mRNAs export from the nucleus.  The CBC complex is essential for a pioneer round of mRNA translation, before steady state translation when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E.  The pioneer round of mRNA translation mediated by the CBC complex plays a central role in nonsense-mediated mRNA decay (NMD), NMD only taking place in mRNAs bound to the CBC complex, but not on eIF4E-bound mRNAs.  The CBC complex enhances NMD in mRNAs containing at least one exon-junction complex (EJC) via its interaction with UPF1, promoting the interaction between UPF1 and UPF2.  The CBC complex is also involved in 'failsafe' NMD, which is independent of the EJC complex, while it does not participate in Staufen-mediated mRNA decay (SMD).  During cell proliferation, the CBC complex is also involved in microRNAs (miRNAs) biogenesis via its interaction with SRRT/ARS2, thereby being required for miRNA-mediated RNA interference.  The CBC complex also acts as a negative regulator of PARN, thereby acting as an inhibitor of mRNA deadenylation.  In the CBC complex, NCBP2/CBP20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires NCBP1/CBP80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure.  The conventional cap-binding complex with NCBP2 binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus (By similarity).
What are the official names of this protein?
Nuclear cap-binding protein subunit 2, 20 kDa nuclear cap-binding protein, NCBP 20 kDa subunit, CBP20.
What is the protein family that this protein belongs to?
Belongs to the RRM NCBP2 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: HIS7_RHIWR
Sequence: MRTASITRNTSETAIAVELNLDGTGAYSVATGIGFLDHMLEQLSRHSLIDLTVKIDGDLHIDQHHTTEDSGIAIGEALAKALGDKKGITRYGHAYAPMDETLTRVALDISGRPWTVWKVDLKGPRLGEWDTELIEHWFQSFAQAAGITLHVENLYGTNQHHIVESCYKGLARALRTAVEIDPRKADSIPSTKGML
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROK_BACAC
Sequence: MKSIYITGYMGAGKTTIGKALSKELHMDVVDTDQKIEEKQGKVIRDIFAEEGEMAFREYESEMLCSLPVDNVIITTGGGIVEREENRKWMKENGTVVYLYCDPHVIAERLREDTTRPLFQKKDIDAFVTKFESRRAYYEEAHIHIDTTNKSVKQIMNELKEKINE
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSP70_ONCTS
Sequence: MSSAKGPSIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPNNTVFDAKRLIGRKFNDQVVQADMKHWPFKVVSDGGKPKVQVDYKGENKSFNPEEISSMVLVKMREIAEAYLGQKVSNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGMDKGMSRERNVLIFDLGGGTFDVSILTIEDGIFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRALRRLRTACERAKRTLSSSSQASIEIDSLFEGIDFYTSITRARFEEMCSDLFRGTLEPVEKALRDAKMDKAQIHDVVLVGGSTRIPKVQKLLQDFFNGRELNKSINPDEAVAYGAAIQAAILSGDKSENVQDLLLLDVAPLSLGIETAGGVMTALIKRNTTIPSKQTQTFTTYSDNQPGVMIQVYEGERAMTKDNNLLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQDADKYKAEDDAQREKIAAKNSLESYAFNMKSSVEDDNMKGKISQEDKKKVVDRCDQTISWLENNQLGDKEEYEHQLKELEKVCQPIITKLYQQGGMPTGCCGDQARTSSGDSSQGPTIEEID
What are the official names of this protein?
Heat shock 70 kDa protein, HSP70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: YTFA_ECOLI
Sequence: MHSENQSKGVHYAKSQRLLEINHAHLQLMESLLDEGKKHNIFKPDIDPLQVNINIAALGGYYLINQHTLGLVYHISMVSPQALEARRKVIKETILSWLLVDPSSTAHE
What are the official names of this protein?
Putative uncharacterized protein YtfA.
Protein: MURA_THEAB
Sequence: MGYFKVKNSILNGNVRISGAKNSALPILAATILSSEKLEIENVPDLLDVQTMIEILRKIGKKVIFENNKVTLNGTVENHVVPYDLVRKMRASFNVAGPLAVILGESKVSLPGGCAIGVRPVDYHIMGLKKLGFEVEIEHGEVYIKKGKKEKEVIINLPFPSVGATEHLMTTAALMEGTTVIENAAMEPEIVDLQNFLNSLGAKIQGAGSRKIVIEGVNSLNGGSYKVIPDRIEAGTYAIAIAATGGKGYIEEIIPEHLEILWEILKETGTNVIIEKNRVFVDGEGKKRGININIQPYPGFPTDLQPQILVYLSLADGVSMVVENVFKNRFHHIDELVRMGADIRVVDGTAIVNGVKKLSGTKVEGTDLRATAALIIAGLVAEGTTEVHNDFHVLRGYENIVEKIRHLNGEIEHIV
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLV_STAS1
Sequence: MSTSIHATTIFAVQHNGHAAMAGDGQVTLGEQVIMKQTARKVRRLYNDKVLAGFAGSVADAFTLFEKFETKLQQFSGNLERAAVELAQEWRGDKQLRQLEAMLIVMDETSILVVSGTGEVIVPDDNLIAIGSGGNYALSAGRALKRNATHLSASEMAYESLKVASDICVFTNDRIIVENL
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VE4_BPV2
Sequence: MANDKEIAQTEFPHQKDLKETLQEKKPSQPSLSLLCSAPPPAYPSEQASVGYGTVLARTPTIFLQARGALFSALPPPRCRARYRWTWHQGRKKKKINRPTQQRRNL
What is the function of this protein?
Contributes to multiple aspects of the viral life cycle including viral genome amplification, suppression of suprabasal cell differentiation and egress of newly formed virions.  Induces host cell cycle arrest at the G2 phase by associating with and preventing the nuclear entry of host CDK1/cyclin B1 complexes.  Inhibits cellular DNA replication by preventing loading of host replication licensing proteins MCM2 and MCM7 onto chromatin.  Within the cytoplasm, associates with host kinase SRPK1, a splicing factor regulator, and inhibits its activity.  Therefore, E4 favors expression of late viral transcripts by inhibiting SRPK1-mediated phosphorylation of host serine-arginine (SR) proteins that have critical roles in mRNA metabolism.  Late in the infectious cycle, E4 also acts to diminish the integrity of the keratinocyte by disrupting the keratin cytoskeleton and inducing apoptosis through alteration of mitochondrial function to facilitate egress of the newly formed virions.
What are the official names of this protein?
Probable protein E4.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E4 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: MINE_AGRRK
Sequence: MNIFRLFGKQRTAPAARERLQLLLAHERSSVGSDLVFLLREEILAVIEKHVQLDRDKVQVKMDCNEHVSTLEIDVEIPLNATVRAA
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: MINC_SALTI
Sequence: MSNTPIELKGSSFTLSVVHLHEAEPEVIRQALEDKIAQAPAFLKHAPVVINVSGLESPVNWPELHKIVTSTGLRIIGVSGCKDASLKVEIDRMGLPLLTEGKEKAVRPAPVEPATPSEPPQNANPITKTRLIDVPVRSGQRIYAPQCDLIVTSHVSAGAELIADGNIHVYGMMRGRALAGASGDREAQIFCTHLTAELVSIAGVYWLSDKIPAEFYGKAARLRLADNALTVQPLN
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: PSMA2_STAAT
Sequence: MGIIAGIIKFIKGLIEKFTGK
What is the function of this protein?
Peptide which can recruit, activate and subsequently lyse human neutrophils, thus eliminating the main cellular defense against infection.
What are the official names of this protein?
Phenol-soluble modulin alpha 2 peptide.
What is the protein family that this protein belongs to?
Belongs to the phenol-soluble modulin alpha peptides family.
Protein: RS7_CITK8
Sequence: MPRRRVIGQRKILPDPKFGSELLAKFVNILMVDGKKSTAETIVYSALETLAQRSGKSELEAFEVALENVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALAMRWIVEAARKRGDKSMALRLANELTDAADNKGTAVKKREDVHRMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: XYNB_ASPFU
Sequence: MVSFSSLVLAASTVAGVLATPGSEQYVELAKRQLTSSQTGTNNGYYYSFWTDGGGQVTYTNGNGGQYQVDWNNCGNFVAGKGWNPASEKAVTYSGSWQTSGNGYLSVYGWTTSPLVEFYIVESYGSYDPSTGATHLGTVESDGATYNLYKTTRTNAPSIQGTATFDQYWSVRTSHRQSGTVTTKNHFDAWRNAGLQLGNFDYMIVATEGYQSSGSATITVS
What is the function of this protein?
Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.
What are the official names of this protein?
Probable endo-1,4-beta-xylanase B, Xylanase B, 1,4-beta-D-xylan xylanohydrolase B, Endo-1,4-beta-xylanase G1, Xylanase G1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 11 (cellulase G) family.
What are the subcellular locations of this protein?
Secreted.
Protein: FSLO_DICDI
Sequence: MKKLNYLLIVSFIFILNLLISKSQVLIDVTAKCELIDSLSPCKDNLNYTHIYLPTGYTQAAISAQITPLFQQASILPTDCQSNLKNLLCISSYMECNENIPNISPSFPLPSYPCNKYCEKVKDVCSAYMAILGPYVNCSAVQNGNEFFPHTGTDYDLTAYGGSANEEIQCSGPNLASNSTSAPIKFCPSPLIWVDSDTINNKRAYQETTPNCVLPCPTNVYTEKEYKTKFYSEAILFSFSTACSFYLIFTFGVFPNKYTNRNWIIVYLGITAICLAISYAVQEARYGGGDWRCTSDPGRYKSSEDGTCILGGFFFQIGGLGTILFLSLYSFDMFLTMNMMTNKYFIQTSVGMWALIIFYALLPIKHYESSIASAGCWLSNEDNMFWQYFCFYVPSYVATFFLGVFIITSIYKVFKMTVMFKSIKDKRILLLNIRSIIFLIAIMFCVSFSTMYPLYVTYNGDDFSKSVEVYVTCLYANIPNGNEVCPQIVFPQFSLRYMNAITMAIIGIVGLIGLGIDPHILQIYRESIRFKFLLGLVGIQWGTNSPQPLKQGSTTDSSSGSGSGNGSNSGNNRENRKSQRKSRGVSIGMKKINLSASSESSNNLLNQSTPGNLNINESISSIDTSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNYSNNNNNNNNNNNNIERINSDNV
What are the official names of this protein?
Frizzled and smoothened-like protein O.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor Fz/Smo family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ATPB_XYLFM
Sequence: MNQGKIVQIIGAIVDVEFPRNNVPKVYNALKIDGTAIILEVQQQLGDGIVRTIALGSTDGLKRNLIATDTGHAITVPVGTGTLGRIMDVLGNPIDEAGPITYTDQWEIHRNAPSYEDQASTTELLETGIKVIDLMCPFAKGGKVGLFGGAGVGKTVNMMELINNIAKAHSGLSVFAGVGERTREGNDFYHEMKDSNVLDKVAMVYGQMNEPPGNRLRVALTGLTIAEYFRDEKDSSGKGKDVLLFIDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTANGSITSIQAVYVPADDLTDPSPATTFGHLDSTVTLSRSIAALGIYPAVDPLDSSSRQMDPLIIGEEHYNTTQRVQQTLQKYKDLKDIIAILGMDELSEDDKLAVSRARKIERFFSQPFHVAEVFTGAPGKYVPLKETIRGFKAIVDGEYDHLPEQAFYMVGNIEEVIEKANKMTA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RAE2_MOUSE
Sequence: MAEKLPTEFDVVIIGTGLPESILAAACSRSGQRVLHVDSRSYYGGNWASFSFTGLQSWLKDYQQNHDSEEGVTATWQDLIHETEEAISLRKKDETIQHTEVFCYASQDVEDSVQDTETLQRSSPLEASATPADSLDSASLPKERQSAYSTSYEVPSRHTEESDRELSLPSANVEDSLEKEKYCGDKTDMHTVSGEDKGEHKLVVQDSIEQPKRNRITYSQMVKESRRFNIDLVSKPLYSQGSLIDLLIKSNVSRYAEFKNVTRILAFWEGKVEQVPCSRADVFNSKELSMVEKRMLMKFLTFCLDYEQHSDEYQDFKQCSFSDYLKTKKLTPNLQHFILHSIAMTSESSCTTLDGLQATKNFLQCLGRFGNTPFIFPLYGHGEIPQCFCRMCAVFGGVYCLRHKVQCLVVDKDSGRCKGIIDAFGQRISANYFIVEDSYLPKETCSNVQYKQISRAVLITDQSILKTDSDQQISILVVPPLEPGTTSVRVMELCSSTMTCMKDSYLVHLTCSSSKTAREDLEPVVKQLFIPEAEAEAGKDELRKPRLLWALYFNMRDSSGVSRSSYCGLPSNVYICSGPDWGLGSEHAVKQAETLFQEIFPSEEFCPPPPNPEDIIFEAEG
What is the function of this protein?
Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex.  Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B.  The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.  Less effective than CHM in supporting prenylation of Rab3 family (By similarity).
What are the official names of this protein?
Rab proteins geranylgeranyltransferase component A 2, Choroideremia-like protein, Rab escort protein 2, REP-2.
What is the protein family that this protein belongs to?
Belongs to the Rab GDI family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: GATB_LACTC
Sequence: MGCTFLPLESAFMLQFTRCFGSRTANKGFQLLPDFKLKCGLEIHTQLSTQNKLFSLSTNDPFASANLPNHHTSFFDVSLPGSQPKLNPEVVLFATKLAVALNSKVNLNSHFDRKHYFYADQPMGYQITQHYSPFAKGGFLELLGSLDSIDENSKRIQLVQLQIEQDTGKSVYRGSEGRSLIDLNRSNVPLIELVTQPNFTDLKQIRAFIKKFQNLVRHLGISTGDLETGAMRVDVNLSVNGYSRVELKNLPNTSSILSAIKYEYQRQVGLIQSGEADKYLSSSETRGWTGSSTVKLRSKETTIDYRYMPDPELPSIKISPGTVQSVSQSMPKLPDAVLHDLMSEPYGLALKDAKILAIKGNGHDQLYTQTSLLKYYLDTFSCYSTLAGQQLNPRLPTNWIIHELLGNLNRLQLPLEKAAEAFPPKKFAELLMLIQDDKISKASGKLLLFHILNEINKLSLAQPVDLSALIEGFDLNVIKKIDANELREICTEIVGGISDPKLIEGIVSGKKKNSLKFLIGQGMRVSQGRIKPHLFEQAFKELLKVKW
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial, Glu-AdT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: O10H2_HUMAN
Sequence: MLGLNHTSMSEFILVGFSAFPHLQLMLFLLFLLMYLFTLLGNLLIMATVWSERSLHTPMYLFLCVLSVSEILYTVAIIPRMLADLLSTQRSIAFLACASQMFFSFSFGFTHSFLLTVMGYDRYVAICHPLRYNVLMSPRGCACLVGCSWAGGSVMGMVVTSAIFQLTFCGSHEIQHFLCHVPPLLKLACGNNVPAVALGVGLVCIMALLGCFLLILLSYAFIVADILKIPSAEGRNKAFSTCASHLIVVIVHYGFASVIYLKPKGPHSQEGDTLMATTYAVLTPFLSPIIFSLRNKELKVAMKRTFLSTLYSSGT
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 10H2, Olfactory receptor OR19-23.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NUOB_ACIAD
Sequence: MKYTLTRANPDANQYPLQERQVVNDPLQEEVNKNVFMTRLEDVLHNVVNWGRKNSVWPFNFGTSCCYVEYATTLTGVHDLSRFGAEVIRASPRQADLMIVAGTCFVKMAPVIQRLYEQMLEPKWVISMGACANSGGMYDIYSVVQGVDKIIPVDVYVPGCPPRPEALIQALMLLQDQIQLERRPLSAVIGDDLQPVYKPKMMPERDRKNAERIAVKNLRSMDEIK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL11_HELPH
Sequence: MAKKVVGEIKLQIPAGKANPSPPVGPALGQRGVNIMEFCKAFNERTKDMGSFNIPVIITVYQDKSFTFITKKPPVTDLIKKASGVEKGSDNPLKNKIAKLTHKQVEEIAQLKMEDLNTSTMEAAKKIVMGSARSMGVEVVD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: EIF3I_AEDAE
Sequence: MKPLMLQGHERAITQIKYNREGDLIFSTAKDHKPSVWFSLNGERLGTFNGHQGAVWCVDVDWTTTRLITGSGDMSTKLWDVETGSVLGTIPCNSAARTVNFSYSGNQASYSTDKAMGHNCELFIIDVRNVDSSISNQSPVLKLTMNQQSKITSMLWGALDETVITGHENGSIRIWDLRAAKELNSVNDHTLNINDMQLSSDGTMLVSASKDATAKLFDSESLMCLKTYKTERPVNSAAISPIHEHVVLGGGQEAMEVTTTSTKAGKFDSRFFHLVYEEEFARVKGHFGPINSLAFHPDGKSYATGGEDGFVRVQVFDASYYDFVFE
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit I, eIF3i.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit I family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA222_DRYCN
Sequence: MYPAHLLVLLAVCVSLLGAASVPPQPLNLVQFGYLIQCANHGSRATWHYMDYGCYCGAGGSGTPVDDLDRCCKIHDDCYGDAEKKGCSPKMLAYDYYCGENGPYCKNIKKECQRFVCACDVQAAKCFAGAPYNDANWNIDTTKHCQ
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that inhibits collagen-induced platelet aggregation.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (By similarity).
What are the official names of this protein?
Phospholipase A2 PS22, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GFA_BRASB
Sequence: MTVHIHPYVDNGVKQGSGHFAGGTLVCKCHDRPVKVAVKGDVAHNHACGCTKCWKPSGATFSVIAVVPRQNVTVLENGDKLKIVDPSAVIQRYACTGCGTHMYGRIENTGHPFYGLDFIHPELFQEQGSAAPAFAAFVSSVIESGVKPEQMGEIRARLKELGLEPYDCLSPALMDAIATHVAKAKAA
What is the function of this protein?
Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione.
What are the official names of this protein?
Glutathione-dependent formaldehyde-activating enzyme, S-(hydroxymethyl)glutathione synthase.
What is the protein family that this protein belongs to?
Belongs to the Gfa family.
Protein: UL49_HHV7J
Sequence: MSSLRNLLCRLISPLCKHGSYSHLQLFLIGDVSKSENCVLSMFVTNKKFLSKDLTDNFYRKFLKVWLKCDLDSRNQIKAIFNKMMMTKNFFLLLAYLYFLYRQCKVLKILALYKIQRLTWKQIVERFKQYPIHKLNQLLEIPSFVSFNDLYYYLFQQQLMLPISTHCNIPCMKLFCLRNFEQCNDITLRYAHRASNLTYQDIFHGCSLTVPCGNFIFAMAMAMIENYCYSFDRFLIPLENNNLVPIVLNKQEKHQLPKILTFALTTVLKRSLTSSIISLPVLCFCKTKCLRYAKIDSYLTVICSKCGHCLNSGKERLKGKQTFSLSSMFYYRDRQEKNIIYSMHTDLLYCSLCGGQRLTLEKVYELYEYSVSGIQVKSVSWKAIIGTNSACTILNDSVKFDAIVACSCRTCYSMIHLQNLTINKLLKLISHSTEFQCQDCQNIYRETCLDLEDCGEICTGCKISQLAKCTQHGCDTW
What are the official names of this protein?
Protein U33.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae UL49 family.
Protein: TUSA_SHESA
Sequence: MNDVFSTAQHKLDALGLRCPEPVMMVRKTVRQMAQGETLLIIADDPATTRDIPSFCEFMDHTLVASETSQTPYQYLIKKGL
What is the function of this protein?
Sulfur carrier protein which probably makes part of a sulfur-relay system.
What are the official names of this protein?
Sulfur carrier protein TusA.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NACHO_RAT
Sequence: MASPRTITIVALSVALGLFFVFMGTIKLTPRLSKDAYSEMKRAYKSYVRALPLLKKMGINSILLRKSIGALEVACGIVMTLVPGRPKDVANFFLLLLVLAVLFFHQLVGDPLKRYAHALVFGILLTCRLLIARKPEDRSSEKKALPESAEEQPSLYEKAPQGKVKVS
What is the function of this protein?
Molecular chaperone which mediates the proper assembly and functional expression of the nicotinic acetylcholine receptors (nAChRs) throughout the brain (PubMed:26875622).  Essential for the proper folding, assembly, function and surface trafficking of alpha-7 (CHRNA7), alpha-4-beta-2, alpha-3-beta-2 and alpha-3-beta-4 receptors (PubMed:26875622).  Stably associates with ribophorin-1 (RPN1) and ribophorin-2 (RPN2) (components of the oligosaccharyl transferase (OST) complex) and with calnexin (CANX), both of which are critical for NACHO-mediated effects on CHRNA7 assembly and function (By similarity).  Facilitates the proper folding and assembly of alpha-6-beta-2 and alpha-6-beta-2-beta-3 receptors and acts at early stages of the nAChRs subunit assembly (PubMed:26875622).  Promotes the expression of the alpha-4(2):beta-2(3) stoichiometric form over the alpha-4(3):beta-2(2) form (By similarity).
What are the official names of this protein?
Novel acetylcholine receptor chaperone, Spinal cord expression protein 4, TMEM35 gene-derived unknown factor 1, Transmembrane protein 35A.
What is the protein family that this protein belongs to?
Belongs to the DoxX family.
What are the subcellular locations of this protein?
Peroxisome membrane; Multi-pass membrane protein. Cytoplasmic vesicle. Endoplasmic reticulum membrane; Multi- pass membrane protein. Note=Shedding may lead to a soluble peptide.