PharMolix/UniProtQA huggingface dataset:
Protein: ASTC_ECO7I
Sequence: MSQPITRENFDEWMIPVYAPAPFIPVRGEGSRLWDQQGKEYIDFAGGIAVNALGHAHPELREALNEQASKFWHTGNGYTNEPVLRLAKKLIDATFADRVFFCNSGAEANEAALKLARKFAHDRYGCHKSGIVAFKNAFHGRTLFTVSAGGQPAYSQDFAPLPPDIRHAAYNDINSASALIDDSTCAVIVEPIQGEGGVVPASNAFLHGLRELCDRHNALLIFDEVQTGVGRTGELYAYMHYGVTPDLLTTAKALGGGFPVGALLATEECASVMTVGTHGTTYGGNPLASAVAGKVLDLINTPEMLNGVKQRHDWFVERLNTVNHRCGLFSEIRGLGLLIGCVLNADYAGQAKQISQEAAKAGVMVLIAGGNVVRFAPALNVSEEEVTTGLDRFAAACEHFVSRGSS
What is the function of this protein?
Catalyzes the transamination of N(2)-succinylornithine and alpha-ketoglutarate into N(2)-succinylglutamate semialdehyde and glutamate.  Can also act as an acetylornithine aminotransferase.
What are the official names of this protein?
Succinylornithine transaminase, Succinylornithine aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. AstC subfamily.
Protein: SNMP1_DROAN
Sequence: MNVHRTKLLGASAGVFLFAIIYGWVIFPKILRFMISKQVTLKPGTDIRDLWSNTPFPLHFYIYVFNVTNPDEVTAGGKPRLQEVGPFVFDEWKDKYDLEDDVQEDTVSFTMRNTFIFNQKETLPLTGEEELVIPHPIMQPGGIMVQREKAAMMELAAKGLSIVFPDAKAFIKGRFMDIFFRGMDVDCSSDEFSAKALCSVFYTGEVKQAKQVNQTHFLFSFLGQANHSDAGRFTVCRGVKNNKKLGMVVKFADEPELAIWPDGGECNNFVGTDSTVFPPGLKKEEGLWAFTPDLCRSLGAFYQRKSSYHGMPSMRYSLDLGDARADESLHCFCDDPEDLDTCPPKGTMNLAPCVNGPLIASMPHFYNADPKLVADVEGLNPNEKDHAVYIDFELMSGTPFQAAKRLQFNLDMEPVEGIEAMRGLPKLILPLFWVEEGVHLNKTFTNMVKYTLFLGLKINSGLRWLLIMLSFVGLGSAGFLFYQNSDSLDITLPPKIIKETNNKVADSNKPNEPPHFAADTSIPGTNPPNAKSEKRERY
What is the function of this protein?
Plays an olfactory role that is not restricted to pheromone sensitivity.
What are the official names of this protein?
Sensory neuron membrane protein 1.
What is the protein family that this protein belongs to?
Belongs to the CD36 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: G3P_ASPOR
Sequence: MATPKVGINGFGRIGRIVFRNAIASGDVDVVAVNDPFIETHYAAYMLKYDSTHGRFQGTIETYDEGLIVNGKKIRFFAERDPAAIPWGSAGAAYIVESTGVFTTTEKASAHLKGGAKKVIISAPSADAPMFVMGVNNKEYKTDINVLSNASCTTNCLAPLAKVINDNFGLVEGLMTTVHSYTATQKTVDAPSAKDWRGGRTAAQNIIPSSTGAAKAVGKVIPSLNGKLTGMSMRVPTANVSVVDLTCRTEKAVTYEDIKKTIKAASEEGELKGILGYTEDDIVSTDLIGDAHSSIFDAKAGIALNEHFIKLVSWYDNEWGYSRRVVDLIAYISKVDGQ
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_STRA3
Sequence: MAVFNKLFKRRHSVSEEIKKDDLQEEVEATETEETVEEVIEEIPEKSELELANERADEFENKYLRAHAEMQNIQRRSSEERQQLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKGLEMTRDSLIQALKEEGVEEVEVDSFDHNFHMAVQTLPADDEHPADSIAEVFQKGYKLHERLLRPAMVVVYN
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDL_LARHH
Sequence: MNETMKSRFGKVAVMMGGNSCEREISLMSGQGVLNALRGQGVDAHAFDPAEKPLAALQSEGFDRVFIALHGAFGEDGTLQGALETMGIPYTGCGVMASAIGMDKWRSKLVWKAAGLPVPDFRLLADDSDFAAIEAELGLPMFVKPACEGSSLGVTKVRKAGELAQAYAEARKFDPLVLAEQFVGGGEYTVALLEGRALPAIKIEPATEFYDYDAKYFRDDTVYRCPAGMDDEHELAMRRLAEQGFAVLGGSGWGRIDFLVDEAGQPYLLEINTAPGMTTHSLVPMAAREAGLTYEALCLKVLEAAHVG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK22_CRYJA
Sequence: MNRASTRKIRAVAKHVRMSSNKARRVAHQLRGCTYMEALSILNWMPHRACYPILKVLRSAAANAYHNMGIDKGFLFVLMAEVNEGPIFKRFRPRARGRGYPIQKPTCHISITLEDVTDSNSIMVKK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PRT32_HYDCO
Sequence: ARRRHSMKKKRKSVRRRKTRKNQRKRKNSLGRSFKAHGFLKQPPRFRP
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Sperm protamine R3 isoform 2.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: BBS5_XENLA
Sequence: MLSVLDALWEDRDVRFDISPQQMKMRPGEVLIDCLDSIEDTKGNNGDRGRLLVTNLRVIWHSLALPRVNLAVGYNCIINITTRTANSKLRGQTEALYILTKCNNTRFEFIFTNLVPGSPRLFTSVIAVHRAYETSKMYRDLKLRGALIQNKQLKLLPREQVYDKINGVWNLSSDQGNLGTFFITNVRIVWHANMNDSFNVSIPYLQIRSIKIRDSKFGLALVIESSQQSGGYVLGFKIDPVEKLQDSVKEINSLHRVYSASPIFGVEYEMEEKPQALEELTIEQVQDDVEIEADEHTDAFVVSRLSRISYFTRQIIYILIFTRMYSGWFHHSLTKLHGSIRFNSVTIAADFLYIYISQNGTKIVK
What is the function of this protein?
Required for ciliogenesis.
What are the official names of this protein?
Bardet-Biedl syndrome 5 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the BBS5 family.
What are the subcellular locations of this protein?
Cell projection, cilium membrane. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite.
Protein: KGUA_HUMAN
Sequence: MSGPRPVVLSGPSGAGKSTLLKRLLQEHSGIFGFSVSHTTRNPRPGEENGKDYYFVTREVMQRDIAAGDFIEHAEFSGNLYGTSKVAVQAVQAMNRICVLDVDLQGVRNIKATDLRPIYISVQPPSLHVLEQRLRQRNTETEESLVKRLAAAQADMESSKEPGLFDVVIINDSLDQAYAELKEALSEEIKKAQRTGA
What is the function of this protein?
Catalyzes the phosphorylation of GMP to GDP.  Essential enzyme for recycling GMP and indirectly, cyclic GMP (cGMP) (PubMed:31201273).  Involved in the cGMP metabolism in photoreceptors (By similarity).  It may also have a role in the survival and growth progression of some tumors (PubMed:31201273).  In addition to its physiological role, GUK1 is essential for convert prodrugs used for the treatment of cancers and viral infections into their pharmacologically active metabolites, most notably acyclovir, ganciclovir, and 6-thioguanine and its closely related analog 6-mercaptopurine (PubMed:197968, PubMed:6248551, PubMed:6306664).
What are the official names of this protein?
Guanylate kinase, GMP kinase, Guanylate kinase 1.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Photoreceptor inner segment. Cytoplasm, cytosol. Note=Colocalizes with RD3 in photoreceptor inner segments and to a lesser extent in the outer plexiform layer.
Protein: Y606_METJA
Sequence: MDLEGKCCLIHAIGGIIFGYLANYVYTAGLGIFSGIATLIFLFIGAVIFGHISAKTFGEESLTQKQWLGCGVLPFFLVAIVVWVLKFNGLI
What are the official names of this protein?
Uncharacterized protein MJ0606.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MAD3_MOUSE
Sequence: MEPVASNIQVLLQAAEFLERREREAEHGYASLCPHHSPGTVCRRRKPPLQAPGALNSGRSVHNELEKRRRAQLKRCLEQLRQQMPLGVDCTRYTTLSLLRRARVHIQKLEEQEQQARRLKEKLRSKQQSLQQQLEQLQGLPGARERERLRADSLDSSGLSSERSDSDQEDLEVDVESLVFGTETELLQSFSAGREHSYSHSTCAWL
What is the function of this protein?
Transcriptional repressor.  Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'.  Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation.
What are the official names of this protein?
Max dimerization protein 3, Max dimerizer 3, Max-associated protein 3.
Protein: SRTA_STAA8
Sequence: MKKWTNRLMTIAGVVLILVAAYLFAKPHIDNYLHDKDKDEKIEQYDKNVKEQASKDKKQQAKPQIPKDKSKVAGYIEIPDADIKEPVYPGPATPEQLNRGVSFAEENESLDDQNISIAGHTFIDRPNYQFTNLKAAKKGSMVYFKVGNETRKYKMTSIRDVKPTDVGVLDEQKGKDKQLTLITCDDYNEKTGVWEKRKIFVATEVK
What is the function of this protein?
Transpeptidase that anchors surface proteins to the cell wall (PubMed:10427003, PubMed:10446208, PubMed:10535938, PubMed:11714722, PubMed:14769030, PubMed:15247224).  Recognizes and modifies its substrate by proteolytic cleavage of a C-terminal sorting signal.  Following cleavage, a covalent intermediate is formed via a thioester bond between the sortase and its substrate, which is then transferred and covalently attached to the cell wall (PubMed:10446208, PubMed:10535938, PubMed:11714722, PubMed:14769030, PubMed:15247224).  This sortase recognizes a Leu-Pro-x-Thr-Gly (LPXTG) motif, which is cleaved by the sortase between the threonine and glycine residues (PubMed:10535938, PubMed:11714722, PubMed:14769030, PubMed:15247224).  Utilizes lipid II as the peptidoglycan substrate for the sorting reaction (PubMed:10446208, PubMed:11856734).  Responsible for the display of important virulence factors (PubMed:14769030).  Important for interactions with the host and host colonization during infection (PubMed:10805806, PubMed:14769030).
What are the official names of this protein?
Sortase A, Surface protein sorting A.
What is the protein family that this protein belongs to?
Belongs to the bacterial sortase family. Class A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: NUOH_BACHK
Sequence: MIETLLQSPSSWTNFFIFFGLAVLLLFAVLGFVTYGILAERKVMGFMQGRIGPNQVGGRFGLLQTVADVLKLLLKEDSIPKAADKPLFILAPVIAFAPAFMVLAVIPFTDKFQFADIGVGLLYYIAVSGITTIGVVTGGWASNNKYSLLGGMRAAAQMISYEIPLVMSVIGIVLLAGSLNLNEIVAAQENVWYIFVQPVGFVVFLIAAVAELNRTPFDLPEAESELVSGYHTEYSGFRWAFFMLSEYVYFFGMASLITVLFLGGWNPVMFLGFIPGAVWFALKFSSVVFLLIWFRVTFPRIRGDQLMEFGWKVLLPIALANIFLTALIKELFF
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SERC_SHESR
Sequence: MSAIYNFCAGPAMLPAAVMKKAQQELLDWNGLGVSVMEVSHRGKEFIALTKQAEADLRELMHIPQNYHVLFMHGGGRGQFSAVVNNFLGNQGRALYLVSGQWSSAALAEAQKLAGDAQIDSLNIVEKQNGLNAVVLPDLHKIDADYRYVHYCPNETVDGIEIFDELDSPWPIVADLSSTIMSREIDVSRYGLIYAGAQKNIGPSGLSIVIVRDDMLKLPSLTQSSIMDYRLAVEHDSMFNTPPTFAWYLAAEVFAWLKSLGGVASIAKINQQKAQMLYACIDANPFYKNGVVAANRSQMNVTFQLADESLDGAFLKEAEAASLVALKGHRIVGGMRASLYNAMPLEGVAALVSFMNEFAAKHS
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_TAMPA
Sequence: MTNIRKTHPLIKIINHSFIDLPAPSNISAWWNFGSLLGICLIIQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGLYYGSYTYFETWNIGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVMVHLLFLHETGSNNPSGLISDSDKIPFHPYYTIKDILGILLLILVLMILVLFSPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILMLFPILHMSKQRSMMFRPLSQCMFWILVADLFTLTWIGGQPVEYPFIIIGQLASILYFMIILLILPAISLFENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NADK_LYSSC
Sequence: MKFAIQSRRDAQSNELMELAKTYLQDFGLTYDEEAPEIVVSIGGDGTLLHAFHRYSHLLDQVAFVGIHTGHLGFYADWKPSELEKLVLSIAKKDFNVVEYPLLEVKVEHHNAASNTYLALNEATVKSPDVTLVMDVELNGNQFERNRGDGHSVSTPSGSTAYNKALGGAIIHPTLAALQITEIASINNRVFRTVGSPLILPAHHHCVLRPVNEQNFNMTVDHLQITQGDVKAIVFNVANERVRFARFRPFPFWERVHESFVANE
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FB55_ARATH
Sequence: MFSVNKRTQAFSVFLFFFSVPKVIRYLNKQRSLKEEEKRLEEFQLLLSKLKDVHLPLDLIVEILKKLPTKSLMRFRCVSKPWSFIISKRRDFVESIMARSLRQPPHKLPVFIFHQCDPGTFFTVSSTFSQSTKPKVSIMPGRNHYNAFRYQYVRGFICCSSSVYDLVTIYNPTTRQCLPLPKIESMVLSPKRHKHCYFGYDHVMNEYKVLAMVNDSQELTQTFHVFTLGRDCPQWRKIRGNIDYELISVSRAGVCIDGTIYYVAVRRKDNENYGELFMMSFDVKSERFYHVRTPETLWSPKCTERGLFNHQGKLGCISSNENNISMWIMENAEKQEWSNITFGLLEYPGGDFRTFSGITPAGEIFSMCYPFYNMPLCVHYYNVKQKSYRRVEIESTRLKTRKQPRDIIRVFAIHDFVENTMWL
What are the official names of this protein?
F-box protein At1g52495.
Protein: ARGB_PROMA
Sequence: MKSNNLATEGINSLPLDHGENDAIRVSVLSEALPYIQKFAGRRIVIKYGGSAMSKESLKEAVFRDIALLSSVGAQPVIIHGGGPEINHWLTKLEIKSEFRDGLRITDSNTMDIVEMVLIGRVNKQIVNGINKVGASAVGLCGIDGKLIEARPWGDGSYGLVGEVARVNADVIEPLIANGYIPVISSVASSVEGINYNINADTVAGEIAAAIGAEKLILLTDTSGILKNKSDPLSLIQNIRLSDMRELIDKEVVNGGMTPKAECCIRALAQGVNAAHIIDGRIPHALLLEVFTDKGIGTMIVSRS
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRS7A_ORYSJ
Sequence: MAPEPEDDIMNEKNPRPLDEDDIALLKTYGLGPYSTSIKKVEKEIKEMAKKINDLCGIKESDTGLAPPSQWDLVSDKQMMQEEQPLQVARCTKIISPNTDDAKYVINVKQIAKFVVGLGDKVSPTDIEEGMRVGVDRNKYQIQIPLPPKIDPSVTMMTVEEKPDVTYNDVGGCKEQIEKMREVVELPMLHPEKFVKLGIDPPKGVLCYGPPGTGKTLLARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFQMARSKKACIVFFDEVDAIGGARFDDGVGGDNEVQRTMLEIVNQLDGFDARGNIKVLMATNRPDTLDPALLRPGRLDRKVEFGLPDLEGRTQIFKIHTRTMNCERDIRFELLARLCPNSTGADIRSVCTEAGMYAIRARRKTVTEKDFLDAVNKVIKGYQKFSATPKYMVYN
What is the function of this protein?
The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins.  The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity).
What are the official names of this protein?
26S proteasome regulatory subunit 7A, 26S proteasome AAA-ATPase subunit RPT1A, 26S proteasome subunit 7A, Regulatory particle triple-A ATPase subunit 1A.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ENO_THEMA
Sequence: MYVEIVDVRAREVLDSRGNPTVEAEVVLEDGTMGRAIVPSGASTGKFEALEIRDKDKKRYLGKGVLKAVENVNETIAPALIGMNAFDQPLVDKTLIELDGTENKSKLGANAILAVSMAVARAAANYLGLPLYKYLGGVNAKVLPVPLMNVINGGQHADNNLDLQEFMIVPAGFDSFREALRAGAEIFHTLKKILHEAGHVTAVGDEGGFAPNLSSNEEAIKVLIEAIEKAGYKPGEEVFIALDCAASSFYDEEKGVYYVDGEEKSSEVLMGYYEELVAKYPIISIEDPFAEEDWDAFVEFTKRVGNKVQIVGDDLYVTNVKRLSKGIELKATNSILIKLNQIGTVTETLDAVEMAQKNNMTAIISHRSGESEDTFIADLAVATNAGFIKTGSLSRSERIAKYNQLLRIEEELGKVAEFRGLKSFYSIKR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: SYFA_LEGPH
Sequence: MGRTMLVLINTIQEQASEAIKQATDIVALEQIRVDFLGKKGKLTELLKGLANLSAEEKPKVGQLVNQAKQGISALIETKMIELKEKQLLAKLAAEQIDVTLPGRNHSTGSLHPVTQVKHRINDYFSRLGFDIVEGPEIETEFYNFEALNIPGHHPARAMHDTFYFGDGRLLRTHTSPVQIRTMEQRKPPFRLIAPGRVYRCDSDVTHTPMFHQVEGLLIDKQATLAGLKGLLQDFFAYFFGRELALRFRPSYFPFTEPSAEVDIECTQCNGKGCRSCKFTGWLEVLGCGMVHPNVLIAVNIDPNEYHGWAFGMGMDRLAMLYYGIDDLRMLFENDLTFLRQF
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSM10_HUMAN
Sequence: MAVSHSVKERTISENSLIILLQGLQGRVTTVDLRDESVAHGRIDNVDAFMNIRLAKVTYTDRWGHQVKLDDLFVTGRNVRYVHIPDDVNITSTIEQQLQIIHRVRNFGGKGQGRWEFPPKNCK
What is the function of this protein?
Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing.  Increases U7 snRNA levels but not histone 3'-end pre-mRNA processing activity, when overexpressed.  Required for cell cycle progression from G1 to S phases.  Binds specifically to U7 snRNA.  Binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner.
What are the official names of this protein?
U7 snRNA-associated Sm-like protein LSm10.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ZIPA_ECO8A
Sequence: MMQDLRLILIIVGAIAIIALLVHGFWTSRKERSSMFRDRPLKRMKSKRDDDSYDEDVEDDEGVGEVRVHRVNHAPANAQEHEAARPSPQHQYQPPYASAQPRQPVQQPPEAQVPPQHAPRPAQPVQQPAYQPQPEQPLQQPVSPQVAPAPQPVHSAPQPAQQAFQPAEPVAAPQPEPVAEPAPVMDKPKRKEAVIIMNVAAHHGSELNGELLLNSIQQAGFIFGDMNIYHRHLSPDGSGPALFSLANMVKPGTFDPEMKDFTTPGVTIFMQVPSYGDELQNFKLMLQSAQHIADEVGGVVLDDQRRMMTPQKLREYQDIIREVKDANA
What is the function of this protein?
Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring.  Also required for the recruitment to the septal ring of downstream cell division proteins.
What are the official names of this protein?
Cell division protein ZipA.
What is the protein family that this protein belongs to?
Belongs to the ZipA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type I membrane protein. Note=Localizes to the Z ring in an FtsZ-dependent manner.
Protein: RITA1_XENLA
Sequence: MPDNLYATNMSLDLSITGHSTALPQRKSRSTYRFKAANSYVDESLFGSSGVRVDQTLQWNTAPPSQTPLLWSPGEIKENKKTSSCRPKSTPAGTPRKKIQYRVKSRTPSYCDESLFGGKVEECTWDAPWVKKEDTVKIRPLLWSPSPRLVQQSSMQNAKQGPLRAVHPPETSDSPLGTHKGLGAFWKPPESDSDYSPSPFSARQRQSTPGRETVRSASCSGRVTARRGSVKMQERPPWK
What is the function of this protein?
Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway.  Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of rbpj/rbpsuh, thereby preventing the interaction between rbpj/rbpsuh and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription.  May play a role in neurogenesis.
What are the official names of this protein?
RBPJ-interacting and tubulin-associated protein 1, RBPJ-interacting and tubulin-associated protein.
What is the protein family that this protein belongs to?
Belongs to the RITA family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles rapidly between the cytoplasm and the nucleus.
Protein: SM50_STRPU
Sequence: MKGVLFIVASLIAFATGQDCPAYYVRSQSGQSCYRYFNMRVPYRMASEFCEMVTPCGNGPAKMGALASVSSPQENMEIYQLVAGFSQDNQMENEVWLGWNSQSPFFWEDGTPAYPNGFAAFSSSPASPPRPGMPPTRSWPVNPQNPMSGPPGRAPVMKRQNPPVRPGQGGRQIPQGVGPQWEAVEVTAMRAFVCEVPAGRNIPIGQQPGMGQGGFGNQQPGMGGRQPGFGNQPGMGGRQPGFGNQPGMGGRQPGWGNQPGVGGRQPGMGGQQPGWGNQPGVGGRQPGMGGQPGVGGRQPGFGNQPGMVDNNQAWWTTTRLGNQPGVGGRQPGMGGQPGVGGRQPGVGGRQPGFGNQPGVGGRQPGMGGQQPGMGGQPGVGGRQPGMGGRQPGFGNQPGVGGRQPGMGGQQPNNPNNPNPNNPNNPNNPNPRFNRPRMLQEADALA
What is the function of this protein?
Major matrix protein of the sea urchin embryo spicule.  The function of the matrix proteins is to direct crystal growth in certain orientations and inhibit growth in others.
What are the official names of this protein?
50 kDa spicule matrix protein.
What is the protein family that this protein belongs to?
Belongs to the SM50 family.
Protein: RL11_POLAQ
Sequence: MAKKIIGFIKLQIPAGKANPSPPVGPALGQRGLNIMEFCKAFNAQTQSMEPGLPIPVVITAFADKSFTFIMKTPPATIMIKKAAKIEKGSPRPHTDKVGKITRAQAEEIAKAKMPDLTAADMDAAVRTIAGSARSMGITVEGL
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.