PharMolix/UniProtQA huggingface dataset:
Protein: LIPB_CALBD
Sequence: MCINVCYLGEVEYQEALFIQERIWALRVEKKIGDTLLLLEHPPVITIGRRGSKKNILVSDEFLKKMDVKVFEVSRGGDVTYHGPGQLVGYPIFDLALTDRDIKKFVYLLEEVFIRLLKDQFGKEAHRDENKYTGVWVGNDKIVAIGIAVKKWVTMHGFAFNVNTNLEHFSWIVPCGLKDRGVTSLERLIGSTIRFEDVVDKVQTYFGKVFGKSLNILGKEKLFDLLKI
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CD003_MOUSE
Sequence: MEVSQAASGTDGVRERRGSFEAGRRNQDEAPQSGMNGLPKHSYWLDLWLFILFDLALFVFVYLLP
What are the official names of this protein?
Uncharacterized protein C4orf3 homolog.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: DCUP_BURCJ
Sequence: MAHNLLNDTFLRALLREPTDYTPIWLMRQAGRYLPEYNATRARAGSFLGLAKNPDYATEVTLQPLERFPLDAAILFSDILTIPDAMGLGLDFQVGEGPKFAHPVRTEADVAKLAVPDIEATLGYVTGAVREIRRALTDAQGRQRVPLIGFSGSPWTLACYMVEGGGSDDFRTVKSMAYSRPDLMHRILDVNAQAVAAYLNAQIEAGAQAVMIFDTWGGALADGAYQRFSLDYIRRVVSQLKREHDGERVPVITFTKGGGLWLEEIAATGVDAVGLDWTVNLGAARERVAGRVALQGNLDPTILFAPPAAVREQARAVLDSYGNHPGHVFNLGHGISQFTSPDHVAELVDEVHTHSRAIRSGAAG
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GTFC_AMYOR
Sequence: MRVLLSTAGSRGDVEPLVALAVRLQGLGVEARMCASPASAERLAEVGVPHVPVGLQLEGMLLQEGMPPPSPEEERRLAAKAIDMQFDEVPAAAEGCAAVVAAGELAAAAAVRSVAEMLGIPYFYAAYSPNYLPSPHHAPPEDERTTPGVTDNKVLWDERGQRFAKRYGDTLNSRRASVGLPPVEDVFGYGYSERPWLATDPILAPLPPDFDAVQTGTWILPDERPLSAELEAFLAAGSPPVYLGFGSASGPGIDDAARVAIEAIRAHGRRIVLLSGWADLVRPDDGADCFSVDEVNLQVLFSRAAAAIHHGSAGTEHLATLAGIPQIVIPRHTDQPYYAERVADLGIGVALEGPVPTFDAMSAAVATALAPETRARATAVAGTIRTDGAAVAARLLLDAVSREKSAVLA
What is the function of this protein?
Catalyzes the attachment of dTDP-L-4-epi-vancosamine to chloroorienticin B to form chloroeremomycin in the biosynthesis of glycopeptide antibiotic chloroeremomycin, a member of the vancomycin group of antibiotics.  Also able to use dTDP-L-4-epi-vancosamine and devancoaminyl-vancomycin (DVV) to create epivancomycin.  Acts downstream of GtfA.
What are the official names of this protein?
Glycosyltransferase GtfC.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family.
Protein: CSD_PSEPK
Sequence: MFQPSPWRADFPAIAALQRQHQTYLDSAATTQKPQALLDALSHYYGHGAANVHRAQHLPGALATQAFETSRDKVAAWLNAADSRQIVFTHGATSALNLLAYGLEHRLEAGDEIAISALEHHANLLPWQQLAHRRNLHLVVLPLDAHGRIDQDQALQLIGPRTRVLAISQLSNVLGTWQPLPALLAHARAQGALTVVDGAQGVVHGRQDMQQLGCDFYVFSSHKLYGPDGVGVLYGRAQALELLRHWQFGGEMVQLAEYHSASFRPAPLGFEAGTPPIAGVIGLGATLDYLASLDAHAVAAHEASLHQHLLRGLGDREGVRVLGAPQTALASFVIEGVHNADIAHLLTEQGIAVRAGHHCAMPLLKGLGLEGAIRVSLGLYNDSDDVQRFFDALDQGLELLR
What is the function of this protein?
Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
What are the official names of this protein?
Probable cysteine desulfurase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
Protein: TLP10_ORYSJ
Sequence: MAAVREPREEAAVGEGEGEEEGRWGGLLPELVEEVVRRVEASGGERWPARKDLVSCACVCRRWREAAAAVVRPLPESGRITFPSSLKQPGPKDFPIQCFVKRNKKKSMFYLYLGLLNGTMDKGKFLMAARRFRRGPHTEYVISLDADDLSQGSNAYVGKLRSDFWGTNFKIYDNQPPYDDAKTSSTRSSQRFGSTHRFGSRRICPQISAGNFNVGQISYKYNLLKSRGPRRMFCTMECPSTQETWENSLKTKSLRCTGTTVLRNKAPRWHEHLQCWCLNFHGRVTVASVKNFQLVATADPSHPDSVGDEETVILQFGKVDSNIFTMDYRQPLSAFQAFAICLSSFGTKLACE
What are the official names of this protein?
Tubby-like F-box protein 10, OsTLP10, Tubby-like F-box protein 11, OsTLP11.
What is the protein family that this protein belongs to?
Belongs to the TUB family.
Protein: COL40_CAEEL
Sequence: MEEKQKIAEAESLKKLAFFGISVSTIATLTAIIAVPMLYNYMQHVQSSLQNEVEFCKHRTDGLWDEFHRFETVKGVDSRIKRDTRSRRGGYAEGGAAAGGGGGGGGSCCSCGIGAAGPAGAPGKDGAPGEDGKAGNPGTAGSDAEAAAAPTASDFCFDCPPGPAGPAGGPGPAGPPGPAGADGNTPSGGGEGPAGPPGPPGPAGNPGTDGAPGNPGAPGQVTETPGTPGPAGAAGPPGPPGPAGNPGSAGASEPGPAGPAGDAGPDGAPGNAGAPGAPGEAGAPGSGGGCDHCPPPRTAPGY
What is the function of this protein?
Nematode cuticles are composed largely of collagen-like proteins.  The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment.
What are the official names of this protein?
Cuticle collagen 40.
What is the protein family that this protein belongs to?
Belongs to the cuticular collagen family.
Protein: TOF1_ASPTN
Sequence: MDEELAFGQTVEVVDPDVRAHVYSLVTALGGFNGEDADKYVLGDDALACLRDIRRWLKLYDEKYNRMDVARCLGESNLVNGDLLPILSAWWHGNQGSRYMSRIALACKVELLVPLTWPLEVHAEMPANHLRHIPYLQHVQVLYKRGLLSRGHTPLLRAIIRIALPSMAVSRSERTTRDEGILKLMLYLLRNIAIISTNARLAAEGDEEETSRSATINAFQEQDAFALLLTMCSNVGDDFTMQDMVLLEIVFHLIKGVDVEKLFMSDAQRSAKRTDELSELLSKETSLRREYAKNAPTRHGRFGTMIWVKRDDAKMSTVSGQDVLKDSQATLYKMDQSKKWNKPKQRQKQELSVVNNDFDTPVHLNPIASKNLRMFVEEFLDSGFNPLFTHVRKAIEREADRVMDINSRQYFYAVAWFLEAERTRRVRQREKHSQSEKAAKEFEPDSFSLIASVLNQETFVFLNRSMQYSFDQKDWADLNAEMRCFTQILLTVQEMATSPLEEDQEIAENIQNRIFYEETTHDRILAIVRGYKDQGYGYLDACTELSHVFLRMLERYSKENTDMQIRSRRRAKRKKQLEQKGDENNGEEQDSEEEEMLEAERVSKERKFDFRRFSAKFCNQKCVDTFVSFARFYRELNSDQLKRLHRYFYRIAFKEEMSVLLFRVDIINLFYRMIKGPGGMDSTKPIFKEWEEFVRQLIRRMVKKIDQRPALITEMLFSKINSTMYYLEFGHEKQTISVTRRPPAELVVNPNDAETTEDKIKIVIGALVKDGKNRLVSWLSGVLDSAADEREAFEIQEAAEREENTRASRAPNPMIPVEPSDDDCKNEMFSNAKLRLLMALVKFERLGVEDIPGASWVVPAHLSSADIRDIKSTVDKCLADPFQGTFDREPQAMLQRKFQRENRGSFEPTQEVSFGNDSEGEDTPEFLFPPNPRSKSNALEELKKKRKKCKNDDGEKEPLDEQTIEERRRAREENARSRQAKIKSDLYVHASDEESDDEADEEFFRLEEKRRKEQSERIRQALLLGKVEELANKAGKKTQRKRPSDPQIAGDSESQNKRLRQDIPEDDDDLIMGGSEPDSPGLQTGDHDSDDDLRFEDDLAFRRNRESSAASDRNGPPGEAKEDEDTPVAASGRRRMRAGFVIDSDSE
What is the function of this protein?
Forms a fork protection complex (FPC) with csm3 and which is required for chromosome segregation during meiosis and DNA damage repair.  FPC coordinates leading and lagging strand synthesis and moves with the replication fork.  FPC stabilizes replication forks in a configuration that is recognized by replication checkpoint sensors (By similarity).
What are the official names of this protein?
Topoisomerase 1-associated factor 1.
What is the protein family that this protein belongs to?
Belongs to the timeless family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYM_STRMK
Sequence: MTRTALVTTALPYANGPLHLGHLVGYIQADIWVRARRMSGGKAWFVCADDTHGTPIMLAAEKAGVTPETFIANIQASHERDFAAFGVAFDHYDSTNSAANKALTEQFYLKLEAAGHISRRSVAQFYDPAKGMFLPDRYVKGICPNCGSPDQYGDNCEVCGATYAPTDLKEPRSVISGATPEMRDSEHFFFEVGHFDAFLREWLAGDVALPGVKAKLGEWLNAEGGLRAWDISRDAPYFGFQIPGQPGKYFYVWLDAPIGYLSSFQTLCGRIGEDFEAHLRAGTSTELHHFIGKDIVNFHGLFWPAVLHGTGHRAPTRLHVNGYLTVDGAKMSKSRGTFVMARTFLDAGLEPEALRYYYAAKSGGGVDDLDLNLGDFIARVNADLVGKFVNLASRCAGFISKRFDGQLAAQLPDAAQYQRFVDGLAPIREAYERNDPAAAIRLTMTLADEANRYIDDVKPWVIAKQEGADAQLQAVCSQGLNLFRVLVTALKPVLPATAAQAEAFLAAPVNDWTELAQPLLGHRITDYTPLFTRIDPKKIDAMIDASKDTLQPAAAAAPAAKPAAPAPAPAPAKDEAKSADAPAYIGIDDFAKLDLRIGKVLVCEFVEGSDKLLRFELDAGELGKRQIFSGIRASYGEPEKLVGRSVVFIANLAPRKMRFGLSEGMILSAGFDGGALALLDADSGAQPGMPVR
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DIA2_ASHGO
Sequence: MSEDIIDRSLELGIQCFQGEDYKGAAELFSKSLQLARSYTDRSLEGIREKVGLPKRCLHDPSRVYHPRYLVLLDNRAATWEKLNKLDRALADAAYMITVDAYNLKGYIRRGKVLQKLGRYEEALQVYENGLKQAGEAEKTHAIHAPQKFLDIVYRQRSTIKELLQSRARSSRSLTQQTVAKEPKLKRPATIDSLMPGKKRSSSKAKIDYIATLPVEIIERIMANMDTRSIIRCYSVCKLWKYRLERLPHLYQEFRLSCCYKNMLGYVNFVGALASRTAEYSCRSIQCVSGNVQEEEKSIILLLSRLMIGTRQLALMAKKCKAERIIQHICENKKLRNGVQRLSITAPVHFGHKLNLHELYTRTTSMTHLELVLNFHTPSEHVGGHLFPWQDHAVAETNLESFTLMARNYSVHHVNVIEQFEYSSVLFKRLKKLCITGIDFRLGDRNNLKWISDMPNLQELWLERNTGIEFHELITQIVQVGAPKTLRHLTFREPPNRHFDRMDQSQLGLGEEALREVFQSLESLDLMNTRFDPQLLLLLLQPACENRIARLNIGNCPRLSFARDLEILTLIFQQLPALTDLLLPNVMEYTRQGMEVLRKNIKGMKLKRLDLSFIPSLKGYELLDLLKELKGINPLGLETLTINGCTAVAPQTVDYITRNGYAQKVMCAYERTQWEHLGINSFWYR
What is the function of this protein?
F-box protein component of a SCF ubiquitin ligase complex involved in ubiquitin-dependent protein degradation.  The SCF-DIA2 complex is specifically involved in the pheromone induced degradation of phosphorylated TEC1.  Involved in DNA replication, genome stability, and the control of cell cycle, probably through its association to replication origins to facilitate the ubiquitination of another origin-binding protein (By similarity).
What are the official names of this protein?
Protein DIA2.
What is the protein family that this protein belongs to?
Belongs to the DIA2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KHSE_LISMF
Sequence: MRIRVPATTANLGPGFDSCGLALTLYLTLDIGAEADSWYIEHNIGGGIPHDETNVIIETALNLAPNLTPHHLVMTCDIPPARGLGSSSAAVVAGIELANTLAELNLSKEEKVRIAAEIEGHPDNVAPAVLGNWVVGAKLDGEDFYVRHLFPDCALIAFIPKAELLTSESRGVLPDTLPFKEAVQASSIANVMIAAILRNDMALAGEMMERDLWHEKYRSQLVPHLTQIRDVAKSQGAYAACLSGAGPTVLVFAPRNLANTLQTSLQTLEIDADVLLLDVEGSGAEVFR
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTND_CANAW
Sequence: MVEFYFHDNKDTLENFTEDHNSGEPVSFDQLAEIGVIYKYITTQEELDALATEREYKNRDVVTLNLPAFNNDIDAYNAKMQQFYKEHYHEDEEIRYIAEGEGYFDVRDKQDRWIRAKLSPYDLLILPAGIYHRFTLTNAAKHVKAVRLFKDEPKWEAINRDTGKNTEARELYAKTIAV
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL19_COXBR
Sequence: MNNIIQLLETEQTQGKEIPDFRAGDTVTVQVKVKEGNRERLQAFEGVVIARRHRGLNSSFTVRKVSHGEGVERVFQLYSPLIASIKVNRRGDVRRAKLYYLRNLRGRKAKIKEKI
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: ME3L2_HUMAN
Sequence: MARRYDELPHYPSIADGPAALAGFPEAVPAAPGPYGPHRPPQPLPPGLDSDGLKRDKDEIYGHPLFPLLALVFEKCELATCSPRDGAGAGLGTPRGGDVCSSDSFNEDNTAFAKQVRSERPFFSSNPELDNLMIQAIQVLRFHLLELEKGKMPIDLVIEDRDGGCREDFEDYPASCLSLPDQNNIWIRDHEDSGSVHLGTPGPSSGGLASQSGDNSSDQGVGLDTSVASPSSGGEDEDLDQEPRRNKKRGIFPKVATNIMRAWLFQHLWHPYPSEEQKKQLVQDTGLTILQVNNWFINARRRMVQPMIDQSNRIGQGAAFSPEGQPIGGYTETEPHVAFRPPASVGMSLNLEGEWHYL
What are the official names of this protein?
Putative homeobox protein Meis3-like 2.
What is the protein family that this protein belongs to?
Belongs to the TALE/MEIS homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RLME_SALG2
Sequence: MTGKKRSASSSRWLQEHFSDKYVQQAQKKGLRSRAWFKLDEIQQSDKLFKPGMTVVDLGAAPGGWSQYVVTQIGGKGRIIACDLLPMDPIVGVDFLQGDFRDELVMKALLERVGDSKVQVVMSDMAPNMSGTPAVDIPRAMYLVELALEMCRDVLAPGGSFVVKVFQGEGFDEYLREIRSLFTKVKVRKPDSSRARSREVYIVATGRK
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRAR_ECOLI
Sequence: MSDEADEAYSVTEQLTMTGINRIRQKINAHGIPVYLCEACGNPIPEARRKIFPGVTLCVECQAYQERQRKHYA
What are the official names of this protein?
Protein TraR.
Protein: RL7A_METS3
Sequence: MAKAIYVKFDTPEELANQAEEALKTAQDSGKVAKGTNEVTKFIERGDAALVVIAEDVDPAEIVAHIPVLADEKEIPYIYLPTKEQVGGAAGLTVGTASACIVDAGDAEGDVAEIVEKIAELKE
What is the function of this protein?
Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
What are the official names of this protein?
50S ribosomal protein L7Ae, Ribosomal protein L8e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2123_GRABC
Sequence: MTMLKLALFFLVVSLIAGLFGFTGISAASAGIAKILFVIFLIVFVVLLVMALAAGKAIL
What are the official names of this protein?
UPF0391 membrane protein GbCGDNIH1_2123.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRMA_CAMLR
Sequence: MHFEEKIALNKALFSSLYDKEIQCFKSPLKAYRTRAEFCIYHHENGEISYAMYENKKKIPIKNFEIADEKIQAYMPILLDNLNENLKHKLFGVEFLATKIDLSITLLYHKNIESITQDLQELSKKLNLKLIARSRGKKLVFNGENLKQILNIKNKEIFYEFNNDCFIQPNTTINEKMIEWVIDLLEKEERKDLLELYCGYGNFTIALAKYFNKILATEISKKNIEFALKNCDLNSIKNISFTRLSSEELSQALKKEREFNRLKGIDLDGFNISHVLVDPPRAGLDVSVIELIKKYENIIYISCNPITLRENLEILSQSHEILNLAFFDQFANTSHLECGVHLRLKA
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: METK_RICAH
Sequence: MKNFIFTSESVSEGHPDKMADQISDTVLDEILKHDPSGRVACETFVTTGLVLVGGEITTSTYVDIEQIVRSKIQEIGYNNPNYGFDGSCCAVISSIMKQSPDIAMGVDNANDDEIGAGDQGMVFGYACNETDSLMPAPIYYAHLLMRRQAYLRKQNVLPWLRPDAKSQVTLRYENNKPVAIDAVVLSTQHHPEIQQKDLIEAVIEEIIKPTLPSSWLNKDTKYLINPTGRFVIGGPVADCGLTGRKIIVDSYGGMARHGGGCFSGKDPTKIDRSAAYMARYIAKNVVGAGLADRCEIQISYAIGVAAPVSVYTETFGTSKLSNEQITKLITQHFDMRPGKIIKHLALRTPCYQKTASYGHFGREDADFTWEKLDKVDILK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_AQUPY
Sequence: MKTYEGELIAEGLRFGIVASRFNHALVDRLVEGAIDCILRHGGREEDITLVRVPGSWEIPVAVGELARREEIDAVIAIGVLIRGATPHFDYIASEVSEGLANLSLELRKPITFGVITADTLEQAIERAGTKHGNKGWEAALSAIEMANLFKKLR
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: PLSB_SHESW
Sequence: MPKQDSLWLKSLRWIQKHLVHTIVVPQDPFADLNLDTSRPLAYVMKTESLSDIAALSEVTEKLGLPSPYEPLVVNGVVAPRVVCLQGRKPLFGERAGNEPFLECFMRLLAVHKERPELDIQLVPVSLYWGRTPGKEDDTMKAAVLERENPTWLRKCFMILFLGRHNFVQFSNAVSLRYMADEHGTDMGIAHKLARVARVHFRRQRKVMTGPLLPNRQALFDSLLKSESLRKAIQEEAVSKKISETQSRETAIEYLDEIAANYSDSLVRIAERFLTWLWNKLYSGINIKGAEHIRQLHHDGHEIVYVPCHRSHMDYLLLSYILYYQGMVPPHIAAGINLNFWPAGPLFRRGGAFFIRRSFNGNKLYTAVFREYLDQLFAKGYSVEYFSEGGRSRTGRLLAPKTGMIAMTMNSVLRGIERPVTLVPVYLGYDHVMEVATYHKELSGKKKQKESVWQVFGAIRKLGNFGQGYVNFGEPITLQTFLNEMAPNWRAELADDPEQKPTWLTPAVNVLANRVMTRINDAAAASSVTLTSLALLASEQNALERCLLERQLDLYLTLLKRVPYTSFTSVAEGDGKHLVQQGIDLNKFSVSSDPLGEIVSIDANQAISMTYYRNNIIHLFIIPSLIASCLTHNEQSQRQQIVAIVNDFYPLLKAELFMGIKDIPSYVNQVLDLFIEQGLITESDNLSVVTEHSSQLVLLSGSVSETLQRYAIIFNLLAHRPKMERSELESESHLLAQRLGALHGITAPEFYDKKLYGTLSVKLKELGYLSDKDDKSDVKRIRDQANSLLRASVRQTIVASVTAEHIS
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, GPAT.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DHQS_NITMS
Sequence: MSKSRELIIAPKGSQAQLSKLLPQLEDEGIKMIYLDPKKLGKKKTKLQTVYPSNNANYVVLEKENATKPKGKKVGRKFEVLSNTDIENILTIAKKGLDFVVVEVKDWKIIPLENIIAKLHKIHTKIFAVARTPEEVRKMFSILEVGVDGVIFNTSSINEVREAMVYLGTRSFDMKPAKIIDIKEVGDGERVCVDTASMLHKGEGMLIGSRSNFLFLVHNESVGSSFTSPRPFRVNAGAVHCYTLSPDGTTNYLSEVETGSEVLILNSKGKARRATVGRSKIERRPMLMIKAKAGGEIGGIIAQDAETIRFVKPNGQLVSVTHLKKGDTVMVHSKPATGRHFGMEVSDEYILEK
What is the function of this protein?
Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3-dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis.
What are the official names of this protein?
3-dehydroquinate synthase, DHQ synthase, 3-dehydroquinate synthase II.
What is the protein family that this protein belongs to?
Belongs to the archaeal-type DHQ synthase family.
Protein: TPMT_PSYCK
Sequence: MNPEFWQARWKEKRIGFNQPKVNPLLIKYFSDLKMATGSRIFIPLCGKSIDMIWLANQGFDMVGVELVESAVQEFFAENNISYTIKAHDKNSNIKCYQGQLSGQTIALWVADIFMLRTNDVGRVDAVYDRAALIAMPAELRPQYSQQVIDLSQNAHQLLLTLNYDQNERAGPPFSISHEQIQQYYSAHYQIQELEGKPSTLNAAPEMTVTENVWLLNKP
What are the official names of this protein?
Thiopurine S-methyltransferase, Thiopurine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_LACDB
Sequence: MQGYFITFEGPDGAGKTTVINEVVKAIQGQCKREILVTREPGGSKIAEKIRDIILDPANTEMNAKTEALLYAASRSQHVSEIINPALKRGDLVMSDRFVDSSLAYQGQGRGLGIDEVAQINAFATGHLEPDLTIFLDLDPAQGLARIAKVRSGSEDRLEQEKLAFHEEVYRGYQKVNQAHPDRVKVVDASQDLPQVVAASVKLVKSTFPELF
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: HTF4_MOUSE
Sequence: MNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGMDERGGTTSWGTSGQPSPSYDSSRGFTDSPHYSDHLNDSRLGTHEGLSPTPFMNSNLIGKTSERGSFSLYSRDSGLSGCQSSLLRQDLGLGSPAQLSSSGKPGTPYYSFSATSSRRRPLHDSVALDPLQAKKVRKVPPGLPSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHSSSDLWSSSNGMSQPGFGGILGTSTSHMSQSSSYGSLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGSTSSSPYVAASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLTGTSQWPRAGGQAPSSPSYENSLHSLKNRVEQQLHEHLQDAMSFLKDVCEQSRMEDRLDRLDDAIHVLRNHAVGPSTSLPTSHSDIHSLLGPSHNASIGNLNSNYGGSSLVTNSRSASMVGTHREDSVSLNGNHSVLSSTVAASNTELNHKTPENFRGGVQNQSGSVVPTEIKTENKEKDENLHEPPSSDDMKSDDESSQKDIKVSSRGRTSSTNEDEDLNPEQKIEREKERRMANNARERLRVRDINEAFKELGRMCQLHLKSEKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSAASAEPPNTLPGAHPGLSESTNPMGHL
What is the function of this protein?
Transcriptional regulator.  Involved in the initiation of neuronal differentiation.  Activates transcription by binding to the E box (5'-CANNTG-3') (PubMed:18214987).  May be involved in the functional network that regulates the development of the GnRH axis (By similarity).
What are the official names of this protein?
Transcription factor 12, TCF-12, Class A helix-loop-helix transcription factor ME1, DNA-binding protein HTF4, E-box-binding protein, Transcription factor HTF-4.
What are the subcellular locations of this protein?
Nucleus.
Protein: EX7S_STRT2
Sequence: MSTKKTFEENLQDLEAIVTKLETGDVALEDAIAEFQKGMVLSKDLQKTLEDAEKTLVKVMQADGTEMEMDA
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DECR_RAT
Sequence: MALLARAFFAGVSRLPCDPGPQRFFSFGTKTLYQSIDAPQSKFFPPILKPMLPPNAFQGKVAFITGGGTGLGKAMTTFLSSLGAQCVIASRNIDVLKATAEEITSKTGNKVYAIRCDVRDPDMVHNTVLELIKVAGHPDVVINNAAGNFISPSERLSPNGWKTITDIVLNGTAYVTIEIGKQLIKAQKGAAFLAITTIYAESGSGFVMPSSSAKSGVEAMNKSLAAEWGRYGMRFNIIQPGPIKTKGAFSRLDPTGKFEKDMIERIPCGRLGTVEELANLATFLCSDYASWINGAVIRFDGGEEVFLSGEFNSLKKVTKEEWDVIEGLIRKTKGS
What is the function of this protein?
Auxiliary enzyme of beta-oxidation.  It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in mitochondria.  Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA.
What are the official names of this protein?
2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial, 2,4-dienoyl-CoA reductase [NADPH], 4-enoyl-CoA reductase [NADPH].
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily.
What are the subcellular locations of this protein?
Mitochondrion.