PharMolix/UniProtQA huggingface dataset:
Protein: NLRP3_BOVIN
Sequence: MRMVSVRCKLARYLEDLEDIDFKKFKMHLEDYPSQKGCTSIPRGQTEKADHVDLATLMIDFNGEEKAWAMAKWIFAAINRRDLYEKAKREEPEWENANISVLSQEESLEEEWMGLLGYLSRISICRKKKDYCKKYRKYVRSKFQCIKDRNARLGESVNLNKRFTRLRLIKEHRSQQEREHELLAIGRTWAKIQDSPVSSVNLELLFDPEDQHSEPVHTVVFQGAAGIGKTILARKIMLDWASEKLYQDRFDYLFYIHCREVSLGTQRSLGDLIASCCPGPNPPIGKIVSKPSRILFLMDGFDELQGAFDEHTEALCTNWRKVERGDILLSSLIRKRLLPEASLLITTRPVALEKLQHLLGQARHVEILGFSEARRKEYFLKYFSDEQQAREAFRLIQENEILFTMCFIPLVCWIVCTGLKQQMDSGKSLARTSKTTTAVYIFFLSSLLQSQGGSQENHNSATLWGLCSLAADGIWNQKILFQECDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEDNHGEMRNTPQACSKLPNRDVKVLLENYGKFEKGYLIFVVRFLFGLINQERTSYLEKKLSCKISQKIRLELLKWIEAKANAKTLQIEPSQLELFYCLYEMQEEDFVQRAMSHFPKIEIKLSTRMDHVVSSFCIENCRHVESLSLRLLHNSPKEEEEEEEVRHSHMDRSVLSDFEVAYSQGLVNYLTSSICRGIFSVLSNNWNLTELNLSGNTLGDPGMNVLCETLQQPGCNIRRLWLGQCCLSHQCCFNISSVLSNNQKLVELDLSHNALGDFGIRLLCVGLRHLFCNLKKLWLVSCCLTSASCEDLASVLSTNHSLTRLYLGENALGDSGVGILCEKVKNPHCNLQKLGLVNSGLTSGCCPALSSVLSTNQNLTHLYLQGNALGDMGVKLLCEGLLHRNCKLQVLELDNCSLTSHCCWDLSTLLTSNQSLRKLCLGNNDLGDLGVMLLCEVLKQQGCLLKSLRLCEMYFNYDTKRALETLQEEKPELTIVFEPSR
What is the function of this protein?
Independently of inflammasome activation, regulates the differentiation of T helper 2 (Th2) cells and has a role in Th2 cell-dependent asthma and tumor growth.  During Th2 differentiation, required for optimal IRF4 binding to IL4 promoter and for IRF4-dependent IL4 transcription.  Binds to the consensus DNA sequence 5'-GRRGGNRGAG-3'.  May also participate in the transcription of IL5, IL13, GATA3, CCR3, CCR4 and MAF.
What are the official names of this protein?
NACHT, LRR and PYD domains-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the NLRP family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Inflammasome. Endoplasmic reticulum. Secreted. Nucleus. Note=In macrophages, under resting conditions, mainly located in the cytosol, on the endoplasmic reticulum. After stimulation with inducers of the NLRP3 inflammasome, mitochondria redistribute in the vicinity of the endoplasmic reticulum in the perinuclear region, which results in colocalization of NLRP3 on the endoplasmic reticulum and PYCARD on mitochondria, allowing the activation of inflammasome assembly. After the induction of pyroptosis, inflammasome specks are released into the extracellular space where they can further promote IL1B processing and where they can be engulfed by macrophages. Phagocytosis induces lysosomal damage and inflammasome activation in the recipient cells (By similarity). In the Th2 subset of CD4(+) helper T-cells, mainly located in the nucleus. Nuclear localization depends upon KPNA2. In the Th1 subset of CD4(+) helper T-cells, mainly cytoplasmic (By similarity).
Protein: RS14_CHLTB
Sequence: MAKKSAVAREVKRRKLVEANFQKRAELRKLAKSLSVSEEERERAREALNKMRRDTSPSRLHNRCLLTGRPRGYLRKFAISRICFRQMASMGDIPGVVKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: LHB1_RUBGE
Sequence: MAERKGSISGLTDDEAQEFHKFWVQGFVGFTAVAVVAHFLVWVWRPWL
What is the function of this protein?
Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
What are the official names of this protein?
Light-harvesting protein B-870 beta chain, Antenna pigment protein beta chain, Light-harvesting protein B-875 beta chain.
What is the protein family that this protein belongs to?
Belongs to the antenna complex beta subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: PYRD_SHESM
Sequence: MFYKIAQKVMFQMDPERAHNLAIGSLKMTGNSPLNAFYAQNIAPAPVSFMGLTFPNPVGLAAGMDKDGESIDAFHAMGFGHVEVGTVTPRPQPGNDLPRLFRLKPAKAIINRMGFNNKGVDNLVKNLIAKKTDIMVGVNIGKNKDTPVEQGKDDYLICMDKVYPYAAYIAVNISSPNTPGLRSLQYGDLLDELLSALKTKQLELAEKHKKYVPIALKIAPDLTTEEIENIAQSLIKNKFDGAIATNTTLTRDGVSGLANANESGGLSGKPLTELSTKVIKQLATCLNGQIPIIGVGGINSAEDALAKFDAGATMVQIYSGFIYQGPKLIKEIVEAYRLK
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MOGT1_MOUSE
Sequence: MMVEFAPLNTPLARCLQTAAVLQWVLSFLLLVQVCIGIMVMLVLYNYWFLYIPYLVWFYYDWRTPEQGGRRWNWVQSWPVWKYFKEYFPICLVKTQDLDPGHNYIFGFHPHGIFVPGAFGNFCTKYSDFKKLFPGFTSYLHVAKIWFCFPLFREYLMSNGPVSVSKESLSHVLSKDGGGNVSIIVLGGAKEALEAHPGTFTLCIRQRKGFVKMALTHGASLVPVFSFGENDLYKQINNPKGSWLRTIQDAMYDSMGVALPLIYARGIFQHYFGIMPYRKLIYTVVGRPIPVQQTLNPTSEQIEELHQTYLEELKKLFNEHKGKYGIPEHETLVFK
What is the function of this protein?
Catalyzes the formation of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA.  Probably not involved in absorption of dietary fat in the small intestine.
What are the official names of this protein?
2-acylglycerol O-acyltransferase 1, Acyl-CoA:monoacylglycerol acyltransferase 1, MGAT1, Diacylglycerol acyltransferase 2-like protein 1, Monoacylglycerol O-acyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol acyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ASB8_MOUSE
Sequence: MSSSMWYIMQSIQSKYSLSERLIRTIAAIRSFPHDNVEDLIRGGADVNCTHGTLKPLHCACMVSDADCVELLLEKGAEVNALDGYNRTALHYAAERDEACVEVLLEYGANPNALDGNRDTPLHWAAFKNNAECVRALLESGASVNALDYNNDTPLSWAAMKGNLESVSILLDYGAEVRVINLKGQTPISRLVALLVRGLGTEKEDSCFELLHRAVGQFELRKNGIMPREVTKDQQLCEKLTVLCSAPGTLKTLARYAVRRSLGLQYLPDAVKGLPLPVSLKDYLLLLE
What is the function of this protein?
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
Ankyrin repeat and SOCS box protein 8, ASB-8.
What is the protein family that this protein belongs to?
Belongs to the ankyrin SOCS box (ASB) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS_ACTP7
Sequence: MTQDLSKHTPMMAQYLQLKAQNPDILLFYRMGDFYELFYDDAKKAAALLDISLTKRGASAGEPIPMAGVPYHAVEGYLAKLVSLGESVAICEQIGDPATSKGPVERKVVRIVTPGTVSDEALLPERQDNLVAAIYEEKGVFAIATLDMTSGRFLITELPNKEALAAELQRLLPAEILYAEDFSAAEILNNYKGLRRRPVWEFELVTAINLLNRQFGTQSLAGFGVEKAVVALCAAGCVLHYAQETQRTALPHINSIHLAQNSDTVLLDAATRRNLELTQNLAGGTENTLAAVLDKCVTPMGSRLLKRWIHQPIRDLEKLKKRQDIIDTLQKEQRIELLQPLLQNVGDMERILARVALRSARPRDLTRLRTALAQLPDIAKNAKNLTASLDALVAQIGDFSELHALLERAIIETPPQLIRDGGVIAEGYNAELDEWRELSAGATQYLENLEIREREATGIDTLKIGFNAVHGYYIQISQGQAHKAPMHYVRRQTLKNAERYIIPELKTYEDKVLKAKGASLALEKQLYDELFDLLMPRLGEMQLAAMALSELDVLTNLAERAESLNYVRPTFSLQRGVNIKGGRHPVVEQVLKDPFIANPVFLNAQRHLLVVTGPNMGGKSTYMRQIALISLMAYIGSFVPADSAEIGALDRIFTRIGASDDLASGRSTFMVEMTEMANILHQATENSLVLIDEIGRGTSTYDGLSLAWACAEWLAKKTQSLTLFATHYFELTSLPSQLKGVANVHLDAREHQDSIVFMHSVQEGAASKSYGLAVAALAGVPKQVIQLAKQRLAHLEEISLQTKEAHDNPQGDLLFAADLQETPQIQPLVAQQSELEKALMSIDPDELTPRQALEALYRLKKLMA
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: RS12_STRLI
Sequence: MPTIQQLVRKGRQDKVEKNKTPALEGSPQRRGVCTRVFTTTPKKPNSALRKVARVRLTSGIEVTAYIPGEGHNLQEHSIVLVRGGRVKDLPGVRYKIIRGSLDTQGVKNRKQARSRYGAKKEK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity).
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RL21_LISMH
Sequence: MYAIIETGGKQIKVEAGQEIYVEKLAGEVGDVVTFDKVLFVGGDSAKVGVPFVEGATVTAKVEKQGRAKKLTVYKYKPKKNYHKKQGHRQPYTKLTIDAINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: GRB2_RAT
Sequence: MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
What is the function of this protein?
Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway.
What are the official names of this protein?
Growth factor receptor-bound protein 2, Adapter protein GRB2, Protein Ash, SH2/SH3 adapter GRB2.
What is the protein family that this protein belongs to?
Belongs to the GRB2/sem-5/DRK family.
Protein: ATPE_LACDA
Sequence: MAEAEKLFKINIVTPNGLIYSHRGSSVSMRAIDGDRQILYNHLPILTPLTIGEVRVQRGADVDHKVDHIAVSGGIIEFANNVATIIADNAERARNIDLSRAEAAKQRAEAHITEAKEKHDEQLLERAQIALRRAVNRIHVYGALHK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SYY_STAAR
Sequence: MTNVLIEDLKWRGLIYQQTDEQGIEDLLNKEQVTLYCGADPTADSLHIGHLLPFLTLRRFQEHGHRPIVLIGGGTGMIGDPSGKSEERVLQTEEQVDKNIEGISKQMHNIFEFGTDHGAVLVNNRDWLGQISLISFLRDYGKHVGVNYMLGKDSIQSRLEHGISYTEFTYTILQAIDFGHLNRELNCKIQVGGSDQWGNITSGIELMRRMYGQTDAYGLTIPLVTKSDGKKFGKSESGAVWLDAEKTSPYEFYQFWINQSDEDVIKFLKYFTFLGKEEIDRLEQSKNEAPHLREAQKTLAEEVTKFIHGEDALNDAIRISQALFSGDLKSLSAKELKDGFKDVPQVTLSNDTTNIVEVLIETGISPSKRQAREDVNNGAIYINGERQQDVNYALAPEDKIDGEFTIIRRGKKKYFMVNYQ
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLAH_ECOL5
Sequence: MNALTAVQNNAVDSGQDYSGFTLIPSAQSPRLLELTFTEQTTNRFLEQVAEWPVQALEYKSFLRFRVGKILDDLCANQLQPLLLKTLLNRAEGALLINAVGIDDVAQADEMVKLATAVAHLIGRSNFDAMSGQYYARFVVKNVDNSDSYLRQPHRVMELHNDGTYVEEITDYVLMMKIDEQNMQGGNSLLLHLDDWEHLGLFFRHPLARRPMRFAAPPSKNVSKDVFHPVFDVDQQGRPVMRYIDQFVQPKDFEEGVWLSELSDAIETSKGILSVPVPVGKFLLINNLFWLHGRDRFTPHPDLRRELMRQRGYFAYATHHYQTHQ
What is the function of this protein?
Acts as an alpha-ketoglutarate-dependent dioxygenase catalyzing hydroxylation of glutarate (GA) to L-2-hydroxyglutarate (L2HG).  Functions in a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
What are the official names of this protein?
Glutarate 2-hydroxylase, G-2-H.
What is the protein family that this protein belongs to?
Belongs to the glutarate hydroxylase family.
Protein: GLMM_STUS1
Sequence: MTRKYFGTDGIRGHVGQAPITPDFMLKLGWAAGMAFRKQGKCRILIGKDTRISGYMFESALQAGLSAAGADVLLLGPMPTPAVAYLTRTFHAEAGIVISASHNPHHDNGIKFFSGRGTKLPDEVELMIEELIDTPMTVVESAQLGKASRINDAAGRYIEFCKSSVPTSTDFSGLKLVIDCAHGATYKVAPSVFRELGAEVVVIGAQPDGLNINADVGSTHVGQLQKAVVEHGADLGIAFDGDGDRVMMVDHTGAVVDGDELLYIIATDLQERERLTGGVVGTLMSNLGLELALKAREIPFCRAKVGDRYVIAEMLDKGWVLGGENSGHIVCAQHTTTGDAIIAALQVVLALRRRGQTLAQERLAWHKCPQVLINVRFSGDRDPIAHPSVKAACDSVTERMGGRGRVLLRKSGTEPLVRVMVEGDDEIQVRGMAEELAKVVTEVCA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: DTDA_SULIK
Sequence: MDIKLVYSTSDPVGLTIKKLGYSFEEIDEDVTDFHYKNGEAIVIFSRHESKASIPSLTVHYPGNPSEEVMGGEPKKLGIAYPRLLTSILREIKKIDLDIEKTMEATHHGPTYQNVPVIFVEIGSDKTYWTNERIVRTLVDSTLKGIDKVDETDCRDYISGFGGPHYSKLFTKLADESCIGHVISKHYVDKLDDKVIIQAIANSVNNINKVVIDSLNLKQRERIIAALKSFDIHIQLR
What is the function of this protein?
D-aminoacyl-tRNA deacylase with broad substrate specificity.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, D-tyrosyl-tRNA(Tyr) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DtdA deacylase family.
Protein: NRL3_ARATH
Sequence: MSSTEEMSSVKNTTQVIGVDPSSTVRVTIVQSSTVYNDTPATLDKAEKFIVEAASKGAKLVLFPEAFIGGYPRGFRFGLAVGVHNEEGRDEFRNYHASAIKVPGPEVERLAELAGKNNVHLVMGAIEKDGYTLYCTALFFSPQGQFLGKHRKVMPTSLERCIWGQGDGSTIPVYDTPIGKIGAAICWENRMPLYRTALYAKGIEIYCAPTADYSLEWQASMIHIAVEGGCFVLSAHQFCKRREFPEHPDYLFNDIVDTKEHDPTVSGGGSVIISPLGKVLAGPNYESEGLVTADLDLGDIARAKLYFDVVGHYSKPDIFNLTVNEHPKKPVTFMTKVEKAEDESNK
What is the function of this protein?
Can convert indole-3-acetonitrile to the plant hormone indole-3-acetic acid.
What are the official names of this protein?
Nitrilase 3.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Tightly associated with the plasma membrane.
Protein: Y2188_DICDI
Sequence: MFTENQNNNQRHALKTEIKTVFNSDSGVTYFSILIETSSKMSLYNVIIKTFITQLQKANRECQIQIITYGDSVNTIFEFDSEPNELKDSLKEIKFSKDNEEAKLGEAMRMCFNNIESNWSSDLMSKIIIISSGQSTDDSSDDLVDILSLDNNSIYGLAGCNLANKSSDEAVKDLQSLLPDQKVIPLGKNPSQDIRLLMNGGGGAANGGGAANGASSSDEHSINCPVNIEVYPHTNETKSIKDDLLLDVVIKPDGNTASVPSGTKIKFLSNKYYSGYTIQLKQNLVFGEPYEETIKLEFKKGQMEKTQFENFPSKIIFHIELANDRDNVHEGFVALNISYFLGELKSKYRCCIGVEGEIGNGKSTCLNGFVNLFNPVGELEEYFNANRTSGTHVTTSINNTSLKEILSAKHYIHPVQESFHDIDIAWSDSWGFVDTDVQLRHKAEGRIHHGTKKDECTILQPDDRYRIDCFIFVVSIRNFTNPASMQRIEKKIKEVLQMNITPLLAITFSDTLSKNQLQDVMKNKVAELSVQESNTFIISNYTEKETHKDISKDVQYLRLLTKAVQLCKVKNEKDIMNKVKGISNLSINDNNNSFNQTPIKNQPFFESSSTSSPSPAFFRSPIQQQQQQTSTTSTQSPSPSSSSASTPPPPSQMLNEQPSKTINVTIDVVTDSSGTVLTSFEIESSTNESVSELKCKLINEIDPEMNANDWSITKESGTVLFESARLSSIIKSFDNSDSIKLVLKKKQKLF
What are the official names of this protein?
von Willebrand factor A domain-containing protein DDB_G0292188.
Protein: GD_BHV1S
Sequence: MQGPTLAVLGALLAVAVSLPTPAPRVTVYVDPPAYPMPRYNYTERWHTTGPIPSPFADGREQPVEVRYAASAAACDMLALIADPQVGRTLWEAVRRHARAYNATVIWYKIESGCARPLYYMEYTECEPRKHFGYCRYRTPPFWDSFLAGFAYPTDDELGLIMAAPARLVEGQYRRALYIDGTVAYTDFMVWLPAGDCWFSKLDAARGYTFSACFPAREYEQNKVLRLTYLTQYYPQEAHKAIVDYWFMRHGGVVPPYFEESKGYEPPPAADGGSPAPPGDDEAREDEGETEDGAAGREGNGGPPGPEGDGESPTPEANGGAEGEPKPGPSPDADRPEGWPSLEAITHPPPAPATPAAPDAVPVGVGIGIAAAAIACVAAAAAGAYFVYTRRRGAGPLPRKPKKLPAFGNVNYSALPG
What is the function of this protein?
Envelope glycoprotein that binds to host cell entry receptors.  May trigger fusion with host membrane, by recruiting the fusion machinery composed of gB and gH/gL (By similarity).
What are the official names of this protein?
Envelope glycoprotein D, gD, Glycoprotein IV.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein D family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs.
Protein: ISPH_CHLL3
Sequence: MKVNLDRNSSGFCIGVQGTIHVAEEKLRAEIGLYSLGDVVHNEVEVKRLESLGLVTIDDQAFRELRDAPVLIRAHGEPPSTYETARANNLEVTDTTCPVVAKLQRTARQLHLLGYQVIIYGKPVHPEVIGINGHAANSAVIIKHADLSDPAETAPLDLSRKTALISQTTMDVPGFYQLKENLETLFRNAGNPQEGPWTEVRDIDITLGLTGMQPTAPHVYKDTICRQVSSRNSKLHDFALSNDCIIFVAGKKSSNGQVLYNICRDANPRSYFIEDTGDLDEGWLKEANGSPVGSVGICGATSTPMWLLEKVARHIESLER
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: SYH_SULIY
Sequence: MTKFETVRGMKDYIGIDAEKIRYLESTFRDLAIKYGYSEIITPVVEEFKLFALKGGEELRETMYVFKDKADRELSLRPEITPSVARAYIQNLQSSPKPIRLFYFGTVYRYDEPQYGRYREFRQAGIEMIGDSSILADLEVLDLLYNFYDKLNLSNDITIKINNIGIFRKIMDKYNIEDNLQEHILHLIDKNKINEALDILEKNLKNKDIIDFFNKILTKKDTKLEDIESLAELEEVSRLDIKSEFLYLFRLSRILSDLNIKFKIDLGFVRGLAYYTGLIFEVLHPSVQFSIAGGGRYDKLIELYGGLPSPAIGFAIGVERTLLVIKDLKVEEPVNVIVIGMSEDTIPSMFMVSRILRKEEYKVVINTKDQPLSKLLPYYASQGFKVAIIIGKQELEKNMITVRNLITRKQISVPLENIEDAIKQTL
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_STRP2
Sequence: MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDRVKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVAAERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PR8A5_RAT
Sequence: MELALSQPSFFGTLLMLVVSNLLLWEKAASIPACMVEDGGCWDPLREAFNSATQRAETLRNLSDQLYVEFFQNQFSSRQFADLSSQLIRKDETVLKAGTYCHSNRAKPKSRGVNIDIEEYLKMSINFCGFMDQPLFHLVIELSAMEGVPETILSKAKDLEENNRQLLDDLRWILTKVFPTAEIKEEFPSWDYLSFLKSSNKNHKFLAIFNLSSCLDYDTQVHYTLSQILNCLITGKDC
What are the official names of this protein?
Prolactin-8A5, Growth hormone-related placental protein 2, Placental prolactin-like protein C, PLP-C, PRL-like protein C.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: HEM3_RICFE
Sequence: MTNSIRIGTRKSPLALIQTNLVIQQIKQFFPDINCEIVPIITSGDLIQNKPLYDIGGKALFLKEIEQALLDKKIDLAVHSLKDVPGRIPEELVIAAILEREDPRDVFVCLNYKSIEELPQNAVIGSSAVRRKAFIQKIRSDLKVTVFRGNIDSRIKKLMTAEVDATILAYAGLKRLRAFNPEYCHLIEYSQMLPCIGQGVIAVEIRQDDNAMLEICNQINHLPTFELIKPERAFLEYLDANCRTPIAAYSKYLDADNIQTDFMLGNLDCSKIIFHTEVTDINTSKEAGIKAAKMMLNQLDK
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: RECX_ECO57
Sequence: MTESTSRRPAYARLLDRAVRILAVRDHSEQELRRKLAAPIMGKNGPEEIDATAEDYERVIAWCHEHGYLDDSRFVARFIASRSRKGYGPARIRQELNQKGISREATEKAMRECDIDWCALARDQATRKYGEPLPTVFSEKVKIQRFLLYRGYLMEDIQDIWRNFAD
What is the function of this protein?
Modulates RecA activity through direct physical interaction.  Can inhibit both RecA recombinase and coprotease activities.  May have a regulatory role during the SOS response.  Inhibits DNA strand exchange in vitro (By similarity).
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAER_STAEQ
Sequence: MTHLLIVDDEKDIVDICQTYFEYEGYQVTTTTCGKEALKLLSSDIDIMILDIMMPEVSGYDIVKKMKDMQLDIPFIYLTAKTQEHDTIYALTLGADDYIKKPFSPRELVLRTNNLLARMSKSNHSNKIEQLEFDGLVLKNLSKTLTINNIEIPMRIKEFELLWYLASREGEVISKSELLEKVWGYDYYEDANTVNVHIHRIREKLEKHDFLPYTITTVWGLGYKFERSR
What is the function of this protein?
Member of the two-component regulatory system SaeR/SaeS.  Probably functions as a transcriptional regulator via a specific DNA-binding domain, recognizing motifs near the promoter sequences of target genes (By similarity).
What are the official names of this protein?
Response regulator SaeR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CARB_LISW6
Sequence: MPKRDDIKTILVIGSGPIVIGQAAEFDYAGTQACLSLKEEGYRVVLVNSNPATIMTDAEMADKVYIEPITLDFVSRIIRKERPDAILPTLGGQTGLNMAMELSAAGILDECNVEVLGTDLTAIKKAEDREAFRDLMNELGEPVPESDIIHNLDEAYSFVERIGYPVIVRPAYTLGGSGGGICHNEQELIETVTSGLKLSPVTQCLLEKSIAGFKEVEYEVMRDANNNAMVVCNMENIDPVGIHTGDSIVVAPSQTLSDREYQLLRDVSLKIIRALEIEGGCNVQLALDPDSYNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEVRNPVTGTTFAHFEPTLDYVVAKIPRFAFDKFEQADRRLGTQMKATGEVMAIGRSWEEALLKAVRSLEVGADHLLLEEAENADEETLERKICFPEDDRLFFLAAALRRGQTIEQLHEKTKIDLFFLYKLSKSIELENRVKENPQNEAILAEAKRAGFSDAFLATCWNIDEQAIYDLRKAQNLFPVYKMVDTCAAEFESTTPYFYSTYEEENESTRSAKESVIVLGSGPIRIGQGVEFDYATVHSVWAIQQAGYEAIIINNNPETVSTDFSISDKLYFEPLTLEDVMHVIEIEQPLGVVVQFGGQTAINLADGLAKRGVKILGTSLEDTDRAENRDAFEKALEILQIPQPAGKTATSVEEAIKVATDIGYPVLVRPSYVLGGRAMEIVESEEALKHYMTNAVKVNPKHPVLVDRYVSGQEVEVDAISDGENVLIPGIMEHIERAGVHSGDSIAVYPAQRLSQQVKNTIVDYTTRLATGLNIIGMLNIQYVVDGEEVFVIEVNPRSSRTAPFLSKITEIPMANVATRVILGENLIDLGYTPGLAPEKQEIFVKVPVFSFAKLRSVDTSLGPEMKSTGEVMGKDVTLEKALYKGFVASGTTMHDYGTVLLTVADRDKKEAVELAKRFNRIGFTIMATKGTASTLEEAEIPVSQVKKIGENQETLIDYIRNGQVTLVVNTLTTGKRPERDGFQIRRESVENGIPVCTSLDTAEAILRVLESRSFELESMNASEVKQPKVRV
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: NU2C1_AMBTC
Sequence: MIWHVQNENFILDSTRIFMKAFHLLLFHGSFIFPECILIFGLILLLMIDSTSDQKDRPWFYFISSTSLVMSITALLFRWREEPMISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDLITIFVAPECFSLCSYLLSGYTKRDVRSNEATTKYLLMGGASSSILVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALLSITVGIGFKLSPAPFHQWTPDVYEGSPTPVVAFLSVTSKVAASALATRIFDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNDGYASMITYMLFYISMNLGTFARIVSFGPRTGTDNIRDYAGLYTKDPFLALSSALCLLSLGGIPPLAGFFGKLHLFWCGWQAGLYFLVSIGLLTSVVSIYYYLKIIKLLMTGRNKEITPHVRNYRRSPLRSNNSIELSMIVCVIASTIPGISMNPIIAIAQDTFF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 A, chloroplastic, NAD(P)H dehydrogenase, subunit 2 A, NADH-plastoquinone oxidoreductase subunit 2 A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.