PharMolix/UniProtQA huggingface dataset:
Protein: HEM3_BURPS
Sequence: MNSETLPAELPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQILDRTLSKVGGKGLFVKELESALADGRADLAVHSLKDVPMALPEGFALAAVMSREDPRDAFVSNDYASLDALPAGAVVGTSSLRREAMLRARHPRLDVRPLRGNLDTRLAKLDRGDYAAIILAAAGLKRLGLAARIRALLDVDDSLPAAGQGALGIEIAARRADVAAWLAPLHDHASALAVEAERAVSRALGGSCEVPLAAHAVWRGGELHLTGSVSTTDGARVLAAHAHARAATAADALALGRRVSDALERQGARAIVDALVAASAQAQKGGA
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: NUOK1_RHIEC
Sequence: MVIGLSHYLTVSAILFTLGVFGIFLNRKNVIVILMSVELILLAVNINMVAFSHFLNDIVGQVFALFILTVAAAEAAIGLAILVVFYRNRGSIAVEDVNMMKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K 1, NADH dehydrogenase I subunit K 1, NDH-1 subunit K 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VATB2_RAT
Sequence: MALRAMRGIVNGAAPELPVPTGGPMAGAREQALAVSRNYLSQPRLTYKTVSGVNGPLVILDHVKFPRYAEIVHLTLPDGTKRSGQVLEVSGSKAVVQVFEGTSGIDAKKTSCEFTGDILRTPVSEDMLGRVFNGSGKPIDRGPVVLAEDFLDIMGQPINPQCRIYPEEMIQTGISAIDGMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKSKDVVDYSEENFAIVFAAMGVNMETARFFKSDFEENGSMDNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHADVSNQLYACYAIGKDVQAMKAVVGEEALTSDDLLYLEFLQKFEKNFITQGPYENRTVYETLDIGWQLLRIFPKEMLKRIPQSTLSEFYPRDSAKH
What is the function of this protein?
Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:32165585).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (PubMed:32165585).  In renal intercalated cells, can partially compensate the lack of ATP6V1B1 and mediate secretion of protons (H+) into the urine under base-line conditions but not in conditions of acid load (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit B, brain isoform, V-ATPase subunit B 2, Endomembrane proton pump 58 kDa subunit, Vacuolar proton pump subunit B 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Apical cell membrane. Melanosome. Cytoplasm. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein.
Protein: PGK_YERPG
Sequence: MSVIKMTDLDLAGKRVLIRADLNVPVKEGKVTSDARIRASLPTIEAALKQGAKVMVTSHLGRPTEGEYNEEFSLLPVVNYLKEKLSSPVRLAKDYLDGVEIAAGELVVLENVRFNKGEKKDDEALSKKYAALCDVYVMDAFGTAHRAQASTHGVGKFAPIACAGPLLSAELEALGKALGNPARPMVAIVGGSKVSTKLTVLGALSKIADKLIVGGGIANTFVAAQGHNVGKSLYEADLIPEAKRLLETCDIPVPTDVRVATEFSETAAATLKPANEIKDDEQILDLGDESAERLAEILKNAKTILWNGPVGVFEFPNFRKGTEIVARAIAESEAFSIAGGGDTLAAIDLFGIADQISYISTGGGAFLEFVEGKKLPAVVMLEERAKQ
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPS1_DROME
Sequence: MESFAVAAAQLGPHFAPLSNGSVVDKVTPDMAHLISPYWNQFPAMDPIWAKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITNTPMMGINLYFETWVLGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGRPMTIPLALGKIAYIWFMSSIWCLAPAFGWSRYVPEGNLTSCGIDYLERDWNPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKKMNVKSLRSSEDAEKSAEGKLAKVALVTITLWFMAWTPYLVINCMGLFKFEGLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCVFGKVDDGKSSDAQSQATASEAESKA
What is the function of this protein?
Visual pigments are the light-absorbing molecules that mediate vision.  They consist of an apoprotein, opsin, covalently linked to cis-retinal.
What are the official names of this protein?
Opsin Rh1, Neither inactivation nor afterpotential E protein, Outer R1-R6 photoreceptor cells opsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell projection, cilium, photoreceptor outer segment. Note=Upon white light stimulation, is internalized into the rhabdomere membranes.
Protein: IF2_STRP1
Sequence: MSKKRLHEIAKEIGKSSKEVVEHAKYLGLDVKSHASSVEEADAKKIISSFSKASKPDVTASQTVKPKEVAQPSVTVVKETGSEHVEKTQVSKPKSRNFKAEREARAKEQAARKQANGSSHRSQERRGGYRQPNNHQTNEQGDKRITHRSQGDTNDKRIERKASNVSPRHDNHQLVGDRNRSFAKENHKNGRFTNQKKQGRQEPQSKSPKIDFKARAAALKAEQNAEYSRQSETRFRAQQEAKRLAELARQEAKEAALKAQAEEMSHREAALKSIEEAETKLKSSNISAKSTADNRRKKQARPEKNRELTHHSQEGQKKNKKSWNSQNQVRNQKNSNWNKNKKTKKGKNVKNTNTAPKPVTERKFHELPKEFEYTEGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGDTIELLMVDYGIEAKAKVEVDDADIERFFEDENYLNPENIVERAPVVTIMGHVDHGKTTLLDTLRNSRVATGEAGGITQHIGAYQIEEAGKKITFLDTPGHAAFTSMRARGASVTDITILIVAADDGVMPQTIEAINHSKAAGVPIIVAINKIDKPGANPERVIAELAEYGIISTAWGGECEFVEISAKFNKNIDELLETVLLVAEVEELKADPTVRAIGTVIEARLDKGKGAIATLLVQQGTLHVQDPIVVGNTFGRVRAMVNDLGRRVKSAEPSTPVSITGLNETPMAGDHFAVYADEKAARAAGEERSKRALLKQRQNTQRVSLDNLFDTLKAGEIKTVNVIIKADVQGSVEALAASLVKIEVEGVRVNVVHSAVGAINESDVTLAEASNAVIIGFNVRPTPQARQQADTDDVEIRLHSIIYKVIEEVEEAMKGKLDPVYQEKILGEAIIRETFKVSKVGTIGGFMVINGKVTRDSSVRVIRDSVVIFDGKLASLKHYKDDVKEVGNAQEGGLMIENFNDLKVDDTIEAYIMEEIVRK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_SERP5
Sequence: MARIAGINIPDHKHTVIALTSIFGIGKTRSQSICASTGIAEHVKISELSEEQIEQLREAVAKFTVEGDLRREVTLSIKRLMDLGTYRGLRHRRGLPVRGQRTKTNARTRKGPRKPIKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: CRIS3_HORSE
Sequence: MALLPVLLFLAAVLLPFFPASGQDPGFAALSITKSEVQKEIVNKHNDLRRTVSPLASNMLKMQWDSKTATNAQNWANKCLLQHSKAEDRAVGTMKCGENLFMSSIPNSWSDAIQNWHDEVHDFKYGVGPKTPNAVVGHYTQVVWYSSYRVGCGIAYCPKQGTLKYYYVCQYCPAGNYVNKINTPYEQGTPCARCPGNCDNGLCTNSCEYEDLVSNCDSLKKIAGCEHELLKENCKTTCQCENKIY
What are the official names of this protein?
Cysteine-rich secretory protein 3, CRISP-3, Acidic epididymal glycoprotein 2, AEG2.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Secreted. Note=In neutrophils, localized in specific granules.
Protein: PBL11_ARATH
Sequence: MGGCFSNRIKTDIASSTWLSSKFLSRDGSKGSSTASFSYMPRTEGEILQNANLKNFSLSELKSATRNFRPDSVVGEGGFGCVFKGWIDESSLAPSKPGTGIVIAVKRLNQEGFQGHREWLAEINYLGQLDHPNLVKLIGYCLEEEHRLLVYEFMTRGSLENHLFRRGTFYQPLSWNTRVRMALGAARGLAFLHNAQPQVIYRDFKASNILLDSNYNAKLSDFGLARDGPMGDNSHVSTRVMGTQGYAAPEYLATGHLSVKSDVYSFGVVLLELLSGRRAIDKNQPVGEHNLVDWARPYLTNKRRLLRVMDPRLQGQYSLTRALKIAVLALDCISIDAKSRPTMNEIVKTMEELHIQKEASKEQQNPQISIDNIINKSPQAVNYPRPSIM
What is the function of this protein?
May play a role in the regulation of plant growth and development (Probable).  May be involved in plant defense signaling (By similarity).
What are the official names of this protein?
Probable serine/threonine-protein kinase PBL11, PBS1-like protein 11.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: OPSD_CAMHU
Sequence: LHMIHLHWYQYPPMNPMMYPLLLIFMLFTGILCLAGNFVTIWVFMNTKSLRTPANLLVVNLAMSDFLMMFTMFPPMMVTCYYHTWTLGPTFCQVYAFLGNLCGCASIWTMVFITFDRYNVIVKGVAGEPLSTKKASLWILSVWVLSTAWCIAPFFGWNHYVPEGNLTGCGTDYLSEDILSRSYLYIYSTWVYFLPLAITIYCYVFIIKAVAAHEKGMRDQAKKMGIKSLRNEEAQKTSAECRLAKNAMTTVALWFIAWTPCLLINWVGMFARSYLSPVYTIWGYVFAKANAVYNPIVYAIS
What is the function of this protein?
Photoreceptor required for image-forming vision at low light intensity.  Can use both retinal and 3-dehydroretinal as visual pigment.  Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins.  Signaling via GNAQ probably mediates the activation of phospholipase C.
What are the official names of this protein?
Rhodopsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Note=Detected on the rhabdomere membrane in the photoreceptor outer segment.
Protein: PRT1_ONCKE
Sequence: MPRRRRSSSRPVRRRRRPRVSRRRRRRGGRRRR
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Protamine, Salmine-AI.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: CFAD_ECOLX
Sequence: MDFKYTEEKEMIKINNIMIHKYTVLYTSNCIMDIYSEEEKITCFSNRLVFLERGVNISVRIQKKILSERPYVAFRLNGDILRHLKNALMIIYGMSKVDTNDCRGMSRKIMTTEVNKTLLDELKNINSHDDSAFISSLIYLISKIENNEKIIESIYISSVSFFSDKVRNVIEKDLSRKWTLGIIADAFNVSEITIRKRLESENTNFNQILMQLRMSKAALLLLENSYQISQISNMIGISSASYFIRVFNKHYGVTPKQFFTYFKGG
What is the function of this protein?
Transcriptional activator of the CFA/I adhesin (cfAA) gene of enterotoxygenic escherichia coli at the temperature of 37 degrees Celsius.
What are the official names of this protein?
CFA/I fimbrial subunit D, Colonization factor antigen I subunit D.
Protein: Y325_STRPZ
Sequence: MFQKQERIGLVVYLYYNRDARKLSKFGDLYYHSKRSRYLIIYINKNDLDTKLEEMRRLKCVKDIRPSAFDDIDRQFVGNLHRDETNNHQKG
What are the official names of this protein?
UPF0298 protein Spy49_0325.
What is the protein family that this protein belongs to?
Belongs to the UPF0298 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HMP_YERPE
Sequence: MLDTQTIAIVKSTIPLLAATGPKLTAHFYERMFKHHPELKNIFNMSNQSSGDQREALFNAICAYATNIENLAALLPTVERIAQKHTSLNIQPEHYPIVGEHLIATLDELFSPGQAVLDAWAKAYGVLADVFIQRESQIYQQSETETGGWRTLRRFRIIKKEQQSEVICSFVLAPEDGGQVLHYKPGQYLGIYIEHESLEFQEIRQYSLTTAPNGKTYRIAVKREEQGTVSNLLHRELNEGDIVRIAPPRGDFFLDVSPDTPVALISAGVGQTPMLSMLNTLYSQQHAAPVHWLHAAENGRVHAFADEVSAIAAKMPNLSRHVWYREPDLQDKHGEDYHSQGLMDLSSYQWLADDPKRHYYFCGPLPFMQFIGRQLLAQGIAPEQIHYECFGPHKVI
What is the function of this protein?
Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds.  Therefore, plays a central role in the inducible response to nitrosative stress.
What are the official names of this protein?
Flavohemoprotein, Flavohemoglobin, Hemoglobin-like protein, Nitric oxide dioxygenase, NO oxygenase, NOD.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Protein: CH60_CAUVC
Sequence: MAAKDVYFSSDARDKMLRGVNILANAVKVTLGPKGRNVVIEKSFGAPRTTKDGVSVAKEIELADKFENLGAQMIREVASKTNDKAGDGTTTATVLAQAIVQEGLKSVAAGMNPMDLKRGIDKAVAIAIEDIKTSSKKVTTNAEIAQVGTISANGDKEVGEMIAKAMDKVGNEGVITVEEAKTAETELDVVEGMQFDRGYLSPYFITNADKMEVQLEEPLILLFEKKLSSLQPLLPVLEAVVQSGRPLLIIAEDVEGEALATLVVNKLRGGLRVAAVKAPGFGDRRKAMLEDIAILTGAQVVSEDIGIKLENVSLEMLGRAKKVSITKDDTTIVDGVGEKADIEARIAQIKRQIEDTTSDYDKEKLQERLAKLAGGVAVIRVGGSTEVEVKEKKDRVDDALNATRAAADEGIVPGGGTALLKASKALAGVVGDNDDQTAGIAIVRRALQAPIRQIAENAGVEGSIVVGKILENDNSAFGFNAQTEQYVDLVVDGVIDPAKVVRTALQNAASVAGLLITTEAAIVEAPKKGGGAPAGGGMPGGMGDMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYVB_LEOCM
Sequence: GTACGESCYVLPCFTVGCTCTSSQCFKN
What is the function of this protein?
Probably participates in a plant defense mechanism.  Has anti-HIV activity.
What are the official names of this protein?
Cycloviolin-B.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family.
Protein: BUB3_MOUSE
Sequence: MTGSNEFKLNQPPEDGISSVKFSPNTSQFLLVSSWDTSVRLYDVPANSMRLKYQHTGAVLDCAFYDPTHAWSGGLDHQLKMHDLNTDQENLVGTHDAPIRCVEYCPEVNVMVTGSWDQTVKLWDPRTPCNAGTFSQPEKVYTLSVSGDRLIVGTAGRRVLVWDLRNMGYVQQRRESSLKYQTRCIRAFPNKQGYVLSSIEGRVAVEYLDPSPEVQKKKYAFKCHRLKENNIEQIYPVNAISFHNIHNTFATGGSDGFVNIWDPFNKKRLCQFHRYPTSIASLAFSNDGTTLAIASSYMYEMDDTEHPEDGIFIRQVTDAETKPKST
What is the function of this protein?
Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule (K-MT) attachments.  Promotes the formation of stable end-on bipolar attachments.  Necessary for kinetochore localization of BUB1.  The BUB1/BUB3 complex plays a role in the inhibition of anaphase-promoting complex or cyclosome (APC/C) when spindle-assembly checkpoint is activated and inhibits the ubiquitin ligase activity of APC/C by phosphorylating its activator CDC20.  This complex can also phosphorylate MAD1L1 (By similarity).  Regulates chromosome segregation during oocyte meiosis.
What are the official names of this protein?
Mitotic checkpoint protein BUB3, WD repeat type I transmembrane protein A72.5.
What is the protein family that this protein belongs to?
Belongs to the WD repeat BUB3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Starts to localize at kinetochores in prometaphase I (Pro-MI) stage and maintains the localization until the metaphase I-anaphase I (MI-AI) transition.
Protein: LIAS_DROSE
Sequence: MLRALKTHVEAPIVVATRAASTNAEKLEEIRERLAKGPNFQDFVQNPDNTRSEWEQYDGKLRREKGEEQRLRLPPWLKTTIPVGKNYAKIKAQMRELKLSTVCEEARCPNIGECWGGGEHGTQTATIMLMGDTCTRGCRFCSVKTARKPPPLDVNEPVNTATAIASWGLDYIVLTSVDRDDLPDGGSKHIAETVREIKARNSNIFVECLVPDFRGNLECVETIANSGLDVYAHNIETVEKLTPYVRDRRAHYRQTLQVLTEAKRFNPNLITKSSIMLGLGETDEEIENTLKDLREAGVDCVTLGQYMQPTNKHLKVIEYVTPEKFKHWEERGNELGFLYTASGPLVRSSYKAGEFFITSILENRKKRQNATEVPKEQ
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, mitochondrial, Lipoate synthase, LS, Lip-syn, Lipoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TX1B3_HUMAN
Sequence: MSYIPGQPVTAVVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAGLQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLLVTRQSLQKAVQQSMLS
What is the function of this protein?
May regulate a number of protein-protein interactions by competing for PDZ domain binding sites.  Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway.  Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization.  May play a role in the Rho signaling pathway.  May play a role in activation of CDC42 by the viral protein HPV16 E6.
What are the official names of this protein?
Tax1-binding protein 3, Glutaminase-interacting protein 3, Tax interaction protein 1, TIP-1, Tax-interacting protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Recruited to the cell membrane by interaction with membrane proteins.
Protein: NADK2_BACLD
Sequence: MTDRRNIYFFYKKSEETDEQCKKLKQLAEEHGFRVVHHHNEANIIASIGGDGTFLQAVRKTNFRDDCLYVGVAKKGKAHLYADFNIYDTDKMIEATNSEQIEVRKYPLIDVTVDGTSFQCLNEVSIRSSIIKTFVMDVYIDDLHFETFRGDGMIVSTPTGSTAYNKSVDGAIVDPLIPCIQVTELASLNNNTYRTLGSPFILSADRKLTLKIVQDGNDYPIIGLDNEAFSTMNVKEVEVSLSGKMIKTIKLKDNSFWEKVRRTFL
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase 2, ATP-dependent NAD kinase 2.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXS_PSEPG
Sequence: MPTTFQEIPRERPVTPLLDRADTPAGLRRLAEADLETLADELRQELLYTVGQTGGHFGAGLGVIELTIALHYVFDTPDDRLVWDVGHQAYPHKILTGRRNRMLSLRQKDGIAAFPRRSESEYDTFGVGHSSTSISAALGMAIAARLQNSARKSIAVIGDGALTAGMAFEALNHAQEVNADMLVILNDNDMSISRNVGGLSNYLAKILSSRTYASMREGSKKVLSRLPGAWEIARRTEEYAKGMLVPGTLFEELGWNYIGPIDGHDLPTMIATLRNMRDLKGPQFLHVVTKKGKGFAPAEVDPIGYHAITKLEPADKPAAPKKVSGPKYSAVFGQWLCDMAAADNRLVGITPAMKEGSDLVDFSERYPQRYFDVAIAEQHAVTLAAGMACEGSKPVVAIYSTFLQRAYDQLIHDVAVQNLDVLFAIDRAGLVGEDGPTHAGSYDLSYLRCIPGMLVMTPSDENELRKMLSTGHLYNGPAAVRYPRGTGPNAPISGDLQPLEIGKGVVRRQGEKIALLVFGVQLAEAMQVAEQINATVVDMRFVKPLDEALVLELAGSHELLVTIEENAIMGGAGAAVGEFLASQAVLKPLLHLGLPDIYVEHAKPAQMLAECGLDAAGIEASVKARMAKLGL
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: RTPR_NITSB
Sequence: MYVEHFFKLPSQTKELLQNTPYRFGFGLLSEVTFYRSYSRLKEDGTNEHWPDTVIRVTEGIFSIRKNHALNYHLPWDEEQAQIFAKEFALSMLQLRWLPPGRGLWMMGTRYMYERGSAGLYNCAAVDTSNLAHAAEWAMDMLMVGAGVGFNTAWSGKATKPDKKHPKIYVIDDSKEGWVKSVRLLIQSYTDNGPFYRFDYSKIRPAGSPLKTFGGIAPGPEPLKRLHKKIEQILDDYLDKKIDKTRCVVDLFNNIGLCVVSGNIRRSAEIAIGRPGDKTFLHLKDYEKFPERKEYGWISNNSVVIENLDDFHYIDAITSLIASNGEPGVLHLENMQKYGRFGEIVPDRAWLSNPCGEIALESYELCNLSEIFISKCSNEEDFQKLIEYATFYASTVNLLPTHRPETNEIIARNRRIGVSVSGVADAIEKFGLETIIKWLRKGYEKVRTVNERLAKEAGIPVSLKVTCVKPSGTISILAGTSPGMHYPLATYALRRIRIGKTSKLAKLLIDSGLSFEEDIYDKNSYVFAFPIHYDNPRSIKEVDIYEQMLVLTMLQREWADNMVSNTIQFDPTRYDAKDLSQIVKHFLPMIKSLTLLPEKETIYPQMPFESIKKEEFEKRVTQLPKVEWNTLSGHHADSERFCSTQSCQID
What are the official names of this protein?
Probable adenosylcobalamin-dependent ribonucleoside-triphosphate reductase, RTPR.
What is the protein family that this protein belongs to?
Belongs to the class II ribonucleoside-triphosphate reductase family.
Protein: GSTA5_DICDI
Sequence: MTKPTLTYFPVRGRVQFPRCLLEYLGEEYNFNEVKTISDDLRKQLLFKQLPLYQEGDFKIVQTPAIIDYISEKHDFRGKTKEERARAHQCLAGIMEVLDHCLGYSFKMDKQQQEKFRNESPIKKFFEGFEMVLSQNKYLASGEKETYVDLMAFVMVDYVTNLGLMPSGDYPKLISLKKHYESSPQLKKYLESRPQSNF
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
What are the official names of this protein?
Putative glutathione S-transferase alpha-5, GST class-alpha 5.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Alpha family.
Protein: MURB_XANOR
Sequence: MSEHAPLRALNTFHVEATARWLLSVHTPEALPQALAAPEIADQPLLVLGSGSNVLLAGDPPGCVLCFENRDTAIIAHHADHAIVRAGAGVNWHALVLYSLQQGLSGLENLALIPGTVGACPIQNIGAYGAQVGDFIHVVEAFDRHHQQFVRLDAAACALGYRDSVFKQQPERYLIVAVEFNLPLLCELRLDYAGIREELASMGAELARAADVAQAVINIRQRKLPDPDVLGNAGSFFKNPLLPNEQIAALQASFTDMPVYPGEHAGLGKLSAAWLIEQCGWKGRREGDAGVSPEHALVLVNYGTASGAQLLDFARRIAESVRERYSVILEPEPRIIGAHW
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOD_AROAE
Sequence: MTEPRAWFLAGTDTEIGKTFVACALLHAARRDGRSALGMKPVAAGAEWIAGEWLNEDAAQLRAASSFDPGLDRLNPYCLKTPVAPHIAAAEEGVEIDPARIRAAFESLRAQADVVIVEGVGGFRVPLGDRYDTADLARELGLPVILVVGMRLGCISHALLTVEAIAARGLTLAGWIANRIDPAMLRADENLEALRRRIDAPLLGVVPHVAGADPAQVAASLRLPG
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SNED1_HUMAN
Sequence: MRHGVAWALLVAAALGLGARGVRGAVALADFYPFGAERGDAVTPKQDDGGSGLRPLSVPFPFFGAEHSGLYVNNNGIISFLKEVSQFTPVAFPIAKDRCVVAAFWADVDNRRAGDVYYREATDPAMLRRATEDVRHYFPELLDFNATWVFVATWYRVTFFGGSSSSPVNTFQTVLITDGKLSFTIFNYESIVWTTGTHASSGGNATGLGGIAAQAGFNAGDGQRYFSIPGSRTADMAEVETTTNVGVPGRWAFRIDDAQVRVGGCGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKELFPPTALKMERVEESGVSISWNPPNGPAARQMLDGYAVTYVSSDGSYRRTDFVDRTRSSHQLQALAAGRAYNISVFSVKRNSNNKNDISRPAVLLARTRPRPVEGFEVTNVTASTISVQWALHRIRHATVSGVRVSIRHPEALRDQATDVDRSVDRFTFRALLPGKRYTIQLTTLSGLRGEEHPTESLATAPTHVWTRPLPPANLTAARVTATSAHVVWDAPTPGSLLEAYVINVTTSQSTKSRYVPNGKLASYTVRDLLPGRRYQLSVIAVQSTELGPQHSEPAHLYIITSPRDGADRRWHQGGHHPRVLKNRPPPARLPELRLLNDHSAPETPTQPPRFSELVDGRGRVSARFGGSPSKAATVRSQPTASAQLENMEEAPKRVSLALQLPEHGSKDIGNVPGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGVCHHVYKRVYRVHQDICFKESCESTSLKKTPNRKQSKSQTLEKS
What are the official names of this protein?
Sushi, nidogen and EGF-like domain-containing protein 1, Insulin-responsive sequence DNA-binding protein 1, IRE-BP1.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Note=Forms microfibrils within the extracellular matrix and colocalizes with fibronectin (FN1).