PharMolix/UniProtQA huggingface dataset:
Protein: UN105_CAEEL
Sequence: MAEDRIKSKLRRPASIESTMSSRTKPRHKPSPMSILMPHLMVGESFRKYRPHGLRNIRMNGHLDWNQLRKSFEKQSTFHGISHAATADGKWRWFWYTAFTICLLALLIQIFFLISKYRQYGKTVDLDLKFENAPFPSITICNLNPYKKSAIQSNPNTKAMMEAYSRRIGSGDKTEGIAAALSATGGLHAKVRRAKRKAKGKPRLRDRRYHQAFAQCLCDIEQLTGDRKGSCFAAFKGKIEIDTNNTAGFMNLHTSRCLCQLDTVSKALWPCFPYSSWKEKLCSECVDNTGHCPMRFYKGNELYENIKEQVDLCLCHKEYNHCVSTRDDGIILEISPNDELNDLDIGKKIASQLSAQQEKQAEVTTTEAPTVTQALGFEELTDDIAITSQAQENLMFAVGEMSEKAKESMSYELDELVLKCSFNQKDCQMDRDFTLHYDNTFGNCYTFNYNRTAEVASHRAGANYGLRVLLYANVSEYLPTTEAVGFRITVHDKHIVPFPDAFGYSAPTGFMSSFGVRMKQFIRLEPPYGHCRHGGEDAATFVYTGFQYSVEACHRSCAQKVIVEACGCADPMYPVAEMFGNNTKPCQAVNMDQRECLRNTTLWLGELYSKGKEAIIPDCYCHQPCQETNYEVTYSSARWPSGSAKVMECLPGDFLCLEKYRKNAAMVQIFYEELNYETMQESPAYTLTSVLADLGGLTGLWIGASVVSLLEIVTLIVFATQAYVRKRKGSISAQSHHSVPVHRASRVSLNTLHKSSTTQSVKLSVMDIRSIKSIHSNHSSKSKQSILIEDLPPAIQEQSDDEEETTESSRTNGSCRYLAPGEDLPCLCKYHPDGSIRIMKALCPVHGYMVRRNYDYSVSNSEEEDAEDEVHREPEPFYSAPYEHRKK
What is the function of this protein?
Ion channel which is permeable to small monovalent cations.  Shown not to be H+-ion gated.  May be mechanosensitive and is required for growth and muscle development.
What are the official names of this protein?
Degenerin-like protein unc-105, Uncoordinated protein 105.
What is the protein family that this protein belongs to?
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: WDR59_DROME
Sequence: MPPTETLRPGERGTAGGPGAGAPEQTYIVRQSNKYYEHRDSQATAMSVDYSGQWVLLAGRGHLALQRLGQDDGSLRRHERQSKYEVSVAEFAICPSRKEYCAIATSQHIDIVRWGTAEPHYEMSLRGHTRTVTDIDWHGKDPNLLVSCSIDTFSHIWDLREPRKPALSLNAVCMSGATQVGFNRVSGNLLAAAHDGDLRIWDIRKGSCPTHYITAHLNRVHGINWSHKRETCLATASQDGTVKYFDVCNPRRAEKIITTMSPVWRARYTPIGNGLVSIVVPHLGRGENSLLLWSNSKQTDPICSFVGHTDVILDFAWRPNRESSNEIELVTWSRDRTLRVWKIDDNMLKLCEPSAEEIESRFEPDLSELRVPTPPEFLHPRSILVAASLPISTGDGACNTLPMARSPSFGGGYYRREEPHIARSLTDQPTCSLHHEFSLLNTNMPHVEVDTLDAIKRYACFKICAGGHTVILQVTFTTSYPSPSAPPDFQLCQGTTLSSEVSGVLLKVLRCNALQRVKKSRTCLEQCLRALVAAMKKKVAAVGGADRSQLLLQSPRLEGALSSTLHDACIPYPRTSGVHFNAIGMLTTFAQPVNNKRLTLRQHTALTPRTFSSINGSGLLGNVMATAQREANASFYLQERMISGKPGKQRAIRQMNGSPVVHVYDTSSLLHISRRMAREFSLDKCNIAETCRKNGEICRQHGRLDLVPVWLLAELIATPQIPHETLNDLLFYKDPFKKSLLESLIMHYAISGDIQTAVLLACLFDKCPTGGGAIMEKTVRLPPQLNSQISPYHTVLPLDVKSSSSSNTWQQLKQLRSNSWSDSLDLEIKQIQSDAYACSLIRRTKMPLFDQFKRAYAEILFGWQLLSKRALILKHTQNTPPPVQGVEFVTECRKCAKPKRTPKCEPCKRPVLFCVLCRLPVKGAANACLACGHGGHIDHMMQWFEKHNVCATCGCKCLERTSELLALLS
What is the function of this protein?
A component of the GATOR subcomplex GATOR2 which functions as an activator of the amino acid-sensing branch of the TORC1 signaling pathway.  The two GATOR subcomplexes, GATOR1 and GATOR2, regulate the TORC1 pathway in order to mediate metabolic homeostasis, female gametogenesis and the response to amino acid limitation and complete starvation.  GATOR2 activates the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex, controlling the switch to cell proliferation and growth under nutrient replete conditions and during female oocyte development.
What are the official names of this protein?
GATOR complex protein Wdr59.
Protein: DUHM_BPW14
Sequence: MNPFNIISDTGVSAAVYAGLSRAKCTGQYKECRNGGSTFLRNVKFHITDPRNRNLTLNGRKSNIFQMVAETFWVMSGSGNIKEFLEFFLPRAPQYSDDGINWHGAYGPRMYAHNQLQSAIDLLIKDKDTRRAYVMIADPTLDSAPAIEAAYGVGHSPKDVPCNREIHINIIEDKLCMKVIQRSGDMLFGTGSINPFEFTFLQELLSEATGYALGDYQWDVTDAHYYKAFEDQVNDVLRSEQTFWPNDGKPLGTRFTSATKMQEFFAGVVRVWVKQINRLIDLGDAHYAINDLFADYGVLPEGRLRDYAKMVTFYIAAKQGEIEGDFKALLTNIPTNTDLGQAILTSPFRKFGVVLGD
What is the function of this protein?
Catalyzes formation of 5-hydroxymethyldeoxyuridylate (5HMdUMP) as a step in the pathway that replaces dTMP by thymidine hypermodifications in the viral genome (Probable).  As a final result of the pathway of hypermodification, 5-Nalpha-putrescinylthymidine (Nalpha-PutT) substitutes for about 50% of thymidines in the viral DNA (Probable).  These modifications probably prevent degradation of viral genome by the host restriction-modification antiviral defense system (Probable).
What are the official names of this protein?
Deoxyuridylate hydroxymethyltransferase, Deoxyuridylate hydroxymethylase, dUMP hydroxymethylase, dUMP-HMase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family.
Protein: PAND_NEIG1
Sequence: MFRTILGGKIHRATVTEADLNYVGSITVDQDLLDAAGICPNEKVAIVNNNNGERFETYTIAGKRGSGVICLNGAAARLVQKGDIVIIMSYIQLSEPEIAAHEPKVVLVDGNNKIRDIISYEPPHTVL
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YL458_YEAST
Sequence: MSPQTFCILLIFSLSLEKTSLIVWNIFVNLRLGVFLLLVRIFSSVFLSVTFLGLFRTLLPVGRICFLLLLKADRFLTSSRDPYSRFLPSSRIPKKSFHSPCTDFSILPMSIIVPFSSEYLLVHVQQ
What are the official names of this protein?
Putative uncharacterized membrane protein YLR458W.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CDD_ECO45
Sequence: MHPRFQTAFAQLADNLQSALEPILADKYFPALLTGEQVSSLKSATGLDEDALAFALLPLAAACARTPLSNFNVGAIARGVSGTWYFGANMEFIGATMQQTVHAEQSAISHAWLSGEKALAAITVNYTPCGHCRQFMNELNSGLDLRIHLPGREAHALRDYLPDAFGPKDLEIKTLLMDEQDHGYALTGDALSQAAIAAANRSHMPYSKSPSGVALECKDGRIFSGSYAENAAFNPTLPPLQGALILLNLKGYDYPDIQRAVLAEKADAPLIQWDATSATLKALGCHNIDRVLLA
What is the function of this protein?
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
What are the official names of this protein?
Cytidine deaminase, Cytidine aminohydrolase, CDA.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: GCP_CAEEL
Sequence: MSSAAKNFYQVVKSAPKGRFKGIKRDYTVEDVLKLRGSIDIDYTLATRGANKLWQLLHTEPFVPALGAQTGNQAVQMVRAGLKAIYLSGWQVAADANSAGDMYPDQSLYPANSGPELAKRINRSLRRADQIEACEAEDYLAQRDWYAPIVADAEAGFGGALNCFELMKAYIEAGAAGVHYEDQLGSEKKCGHMGGKVLIPTAQHIRHLNASRLAADVCGVPTIIVARTDAESSRLLTSDIDPRDHPYIDYEAGRTIEGFYRLKDSTAIQYCIDRAIQYAPYTDLIWMETSHPTIADAREFAEGVHKQYPDKMFAYNCSPSFNWKKHLSPSQMEKFQKELGAMGFKYQFITLAGYHANSYSMFDLARNYKEKGMLAYSGLQEGEFAAEKHGYTAVKHQREVGTGYFDAVSRAVTGGLSSTTALSGSTEEAQFQTAVASQDEEILSLTAQNVAGDEKILTPDALRFLHDLNTEFNPRRLRLLSKRNQVQADINNSLWFPDFNKETEVLRSDQGWKGAEIPRDLQDRRVEITGPTDRKMVINAMNSGANVFMADFEDSNSPTWRNQLEGQINLYDAVRNNISYTHPTTKKEYTLNEKHAVLKVRPRGWHLPEKHVLIHNQPTSGSLFDFGLFVFHNAKALIAQGSGPYFYLPKLQSAEEAQLWADVFKYTEDKLGLARGTIKCTVLIEHLLASFQLHEIIHALKDNIVGLNCGRWDYIFSYIKTFQNHRKFLLPDRFQIGMTAPFMRNYSLEVIKACHLRGIHAMGGMAAQIPIKHDQVANDKAFALVRADKEREATDGHDGTWVAHPGLVPLAKRVFDQMMPKPNQISKNLTRANCTKEDLTVIPEGTRTEAGFRHNISVTLGYLDSWLRGTGCVPLYNLMEDAATAEISRAQLWQWLHHDAKLEDGRTIDAGLVKQTIAAETERRLIRAGSVVNRIPEAADLLEKFVTEEKMSDFLTTDAYDRLVSEGY
What are the official names of this protein?
Bifunctional glyoxylate cycle protein, Gex-3-interacting protein 7.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the malate synthase family.
Protein: NHAA_GEOMG
Sequence: MRKPINLLREFSVPLIAGVITALAWANLDPRGYDALIHQPSFGGVSLHFLVNELFMVLFFGIAAAEITQSCLPGGDLNPPRKAVNPLLATLGGVIGPVLVYLSLNAVIGDPTLTKGWGIPTATDIALAWLVARLVFGAGHPAVSFLLLLAVADDAIGLAIIAVFYPDPVHPTEPMWLFLTVAGIVAAYILRGARAKSYWPYVLVGGGLSWTGLFKAHLHPALALVFIIPFLPHPPRESAHLFEENPRDTSPLARFEHDWKIVVDFGLFLFGLANAGVRFSSVGTATWLVLTALLVGKTAGILTMGSLGKALGFPLPDRVGFKELALTGLVAGMGLTVALFVAGVAFVDPDIEGAAKMGALLSGGVLPVAVALGRILKVRRIP
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPA_HAEDU
Sequence: MQLNSTEISELIKKRIAQFNVVSEAQSTGTIVSVSDGIIRIHGLADVMQGEMIELPGNRYAIALNLERDSVGAVVMGPYADLAEGMTVKCTGRILEVPVGKGLLGRVVNTLGQPIDGKGEIDNDGFSPVEVIAPGVIDRQSVDQPVQTGYKAVDSMVPIGRGQRELIIGDRQTGKTSLVIDAIIAQRDSGIKCIYVAIGQKASTIANVVRKLEEHGALANTIVVVASASESAALQYLAPYSGCAMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNAEYVERFTNGAVTGRTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESSLFNSGIRPAVNPGISVSRVGSAAQTKVIKKLSGGIRTALAQYRELAAFAQFASDLDDATRKQLSHGQKVTELLKQKQFAPMPVSEQALVLFAAEFGYLDGVELERISSFESALLAYANSNHADFMKDLAKSGNFNDSIQQELKTIVENFKKNGAW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL21_NEIG1
Sequence: MYAVVKTGGKQYKVSVGEKLKVEQIPAQLDSQIELTEVLMIADGESVKVGAPFIEGAKVTAKVVAHGRGEKVRIFKMRRRKHYQKRQGHRQNFTQIEIVAIA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: ADCY5_MOUSE
Sequence: MSGSKSVSPPGYAAQTAASPAPRGGPEHRAAWGEADSRANGYPHAPGGSTRGSTKRSGGAVTPQQQQRLASRWRGGDDDEDPPLSGDDPLAGGFGFSFRSKSAWQERGGDDGGRGSRRQRRGAAGGGSTRAPPAGGSGSSAAAAAAAGGTEVRPRSVELGLEERRGKGRAAEELEPGTGIVEDGDGSEDGGSSVASGSGTGAVLSLGACCLALLQIFRSKKFPSDKLERLYQRYFFRLNQSSLTMLMAVLVLVCLVMLAFHAARPPLQIAYLAVLAAAVGVILIMAVLCNRAAFHQDHMGLACYALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLLSALHLAISLHTNSQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQARLHSQRENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGMDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAGRIHITKATLNYLNGDYEVEPGCGGDRNAYLKEHSIETFLILSCTQKRKEEKAMIAKMNRQRTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQESANPEDEVDEFLGRAIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICFVQITIVPHSLFMLSFYLSCFLLLALVVFVSVIYACVKLFPTPLQTLSRKIVRSKKNSTLVGVFTITLVFLSAFVNMFMCNSKNLVGCLAEEHNITVNQVNACHVMESAFNYSLGDEQGFCGSPQPNCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIEFIYVLIVEVPGVTLFDNADLLVTANAIDFSNNGTSQCPEHATKVALKVVTPIIISVFVLALYLHAQQVESTARLDFLWKLQATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDSTYDKAGKTHIKAIADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPPLS
What is the function of this protein?
Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.  Mediates signaling downstream of ADRB1.  Regulates the increase of free cytosolic Ca(2+) in response to increased blood glucose levels and contributes to the regulation of Ca(2+)-dependent insulin secretion.
What are the official names of this protein?
Adenylate cyclase type 5, ATP pyrophosphate-lyase 5, Adenylate cyclase type V, Adenylyl cyclase 5.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell projection, cilium.
Protein: MDH_ACIDE
Sequence: XKKPVRVAVTGAAGQIG
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: PPR97_ARATH
Sequence: MMRSVAVIGKKCLHRHTVLLKGNPRTTLCWERSFAGASSDDCRENLSRKVLQDLKLDDAIGLFGDMVKSRPFPSIVEFSKLLSAIAKMNKFDLVISLGEQMQNLGISHNLYTYSIFINYFCRRSQLSLALAILGKMMKLGYGPSIVTLNSLLNGFCHGNRISEAVALVDQMVEMGYQPDTVTFTTLVHGLFQHNKASEAVALVERMVVKGCQPDLVTYGAVINGLCKRGEPDLALNLLNKMEKGKIEADVVIYNTIIDGLCKYKHMDDAFDLFNKMETKGIKPDVFTYNPLISCLCNYGRWSDASRLLSDMLEKNINPDLVFFNALIDAFVKEGKLVEAEKLYDEMVKSKHCFPDVVAYNTLIKGFCKYKRVEEGMEVFREMSQRGLVGNTVTYTTLIHGFFQARDCDNAQMVFKQMVSDGVHPDIMTYNILLDGLCNNGNVETALVVFEYMQKRDMKLDIVTYTTMIEALCKAGKVEDGWDLFCSLSLKGVKPNVVTYTTMMSGFCRKGLKEEADALFVEMKEDGPLPNSGTYNTLIRARLRDGDEAASAELIKEMRSCGFAGDASTFGLVTNMLHDGRLDKSFLDMLS
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At1g63070, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL27_BRUA2
Sequence: MAHKKAGGSSRNGRDSESKRLGVKKFGGEAVLAGNIIVRQRGTKWHPGANVGLGKDHTIFATVNGSVSFRTKANGRTYVSVNPIAEAAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: VPS37_DICDI
Sequence: MSKPDLNSLSIKMKQINLLKERFSHTIEVVKDSTFKIPFLNVHLLISLPVNFPNSPPAYFLEILQTHQPVSLPPNYQWTQISNLASVTVHIMEPFIKDSRILETLIEQVKRSQAMQQQQQQQQQQQRNQQAQQQYSPPPPYKDQPINKQPAQQQPQPVQQKPQQQQNGTNKIPMIPTEFPELKSKSVEELEELLKNEDSLNAFIYSYDEVSELSNRKSKLLSENERLTKITDPLPNDINDLSANLMTSKQKLEELKRKQEQLQQKKNSIADKYSQQNLLEILNDSISDLESESDNIVHSFLEGNLELKEFKKQFKEKRSSYHSKCANKDLFFK
What is the function of this protein?
Component of the ESCRT-I complex, a regulator of vesicular trafficking process.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 37, ESCRT-I complex subunit VPS37.
What is the protein family that this protein belongs to?
Belongs to the VPS37 family.
What are the subcellular locations of this protein?
Cytoplasm. Endosome. Late endosome membrane; Peripheral membrane protein.
Protein: PA1B2_PONAB
Sequence: MSQGDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGDSMVQLMQQYEIWRELFSPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEAIVQLINTRQPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDTDGGFVHSDGAISCHDMFDFLHLTGGGYAKICKPLHELIMQLLEETPEEKQTTIA
What is the function of this protein?
Alpha2 catalytic subunit of the cytosolic type I platelet-activating factor (PAF) acetylhydrolase (PAF-AH (I)) heterotetrameric enzyme that catalyzes the hydrolyze of the acetyl group at the sn-2 position of PAF and its analogs and modulates the action of PAF.  The activity and substrate specificity of PAF-AH (I) are affected by its subunit composition.  The alpha2/alpha2 homodimer (PAFAH1B2/PAFAH1B2 homodimer) hydrolyzes PAF and 1-O-alkyl-2-acetyl-sn-glycero-3-phosphorylethanolamine (AAGPE) more efficiently than 1-O-alkyl-2-acetyl-sn-glycero-3-phosphoric acid (AAGPA).  In contrast, the alpha1/alpha2 heterodimer(PAFAH1B3/PAFAH1B3 heterodimer) hydrolyzes AAGPA more efficiently than PAF, but has little hydrolytic activity towards AAGPE (By similarity).  May play a role in male germ cell meiosis during the late pachytenestage and meiotic divisions as well as early spermiogenesis (By similarity).
What are the official names of this protein?
Platelet-activating factor acetylhydrolase IB subunit alpha2, PAF acetylhydrolase 30 kDa subunit, PAF-AH 30 kDa subunit, PAF-AH subunit beta, PAFAH subunit beta.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family. Platelet-activating factor acetylhydrolase IB beta/gamma subunits subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AFSQ2_STRCO
Sequence: MTREHQGGTRGLAAARKGFWSGLRFTSLRLRLVLVFGLVALTAAVSASGIAYWLNREAVLTRTQDAVLRDFEQEMQNRAGALPEHPTQDEVQHTAGQMANSSQRFSVLLVAENADGTAVYGSSGGLGGVALSDVPESLRTAVNKEQKLTSANKHPYHLYWQRITDDGTPYLVAGTKVIGGGPTGYMLKSLEPEAKDLNSLAWSLGIATALALLGSALLAQALATTVLKPVHRLGVAARRLGEGKLDTRLRVSGTDELADLSRTFNSAAENLEKRVADMAGREQASRRFVADMSHELRTPLTALTAVTEVLEEELEYAGEGEGEGGSFDPMVEPAVRLVVSETRRLNDLVENLMEVTRFDAGTARLVLDDVDVADQITACIDARAWLDAVDLDAERGVHARLDPRRLDVILANLIGNALKHGGSPVRVSVARADHEIVIRVRDNGPGIPEDVLPHVFDRFYKASASRPRSEGSGLGLSIALENAHIHGGEITAENAPEGGAVFTLRLPQDPSPPADEDGGPDEETEDRGKDAKGQV
What is the function of this protein?
Forms part of a two-component regulatory system AfsQ1/AfsQ2 involved in secondary metabolism.  May activate AfsQ1 by phosphorylation.
What are the official names of this protein?
Signal transduction histidine-protein kinase AfsQ2.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KPYK_CHLMU
Sequence: MIARTKIICTIGPATNTPEMLEKLLDAGMNVARLNFSHGTHESHGRTIAILKELREKRQVPLAIMLDTKGPEIRLGQVESPIKVKPGDRLTLTSKEILGSKEAGVTLYPSCVFPFVRERAPVLIDDGYIQAVVVNAQEHLIEIEFQNSGEIKSNKSLSIKDIDVALPFMTEKDITDLKFGVEQELDLIAASFVRCNEDIDSMRKVLENFGRPNMPIIAKIENHLGVQNFQEIAKASDGIMIARGDLGIELSIVEVPALQKFMARVSRETGRFCITATQMLESMIRNPLPTRAEVSDVANAIHDGTSAVMLSGETASGTYPIEAVKTMRSIIQETEKSFDYQAFFQLNDKNSALKVSPYLEAIGASGIQIAEKASAKAIIVYTQTGGSPMFLSKYRPYLPIIAVTPNRNVYYRLAVEWGVYPMLTSESNRTVWRHQACVYGVEKGILSNYDKILVFSRGAGMQDTNNLTLTTVNDVLSPSLE
What are the official names of this protein?
Pyruvate kinase, PK.
What is the protein family that this protein belongs to?
Belongs to the pyruvate kinase family.
Protein: SYY_CLOBK
Sequence: MSNVYDILKERGYIKQLTHEEEIRELLGKEKISFYIGFDPTADSLHVGHFLQMMVMAHMQKAGHRPIALVGGGTGMIGDPTGKTDMRKMMTKEQIEHNCNCFKKQLAKIIDFSEDKAIMVNNADWLLNLNYIEFLREIGVHFSVNKMLTAECFKSRLEKGLSFLEFNYMLMQGYDFLELNRKYNCVMELGGDDQWSNILAGVDLIRRKESKSAYGMTFTLLTNSEGKKMGKTESGALWLDPEKTSPYEFYQYWRNVADADVEKCLRLITFLPMDEVRRLSSLEGAEINEAKKVLAFEVTKLIHGEEEAQKAKIAAEALFGGNAKDLGNMPTAYIDKNDLNNLLVDLLAKCEIFPSKSEARRLIKQGGLYLNDEKVTDMNLVVTEEHVTEDGIMIRRGKKNFNRIVVE
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TLP1_TAXBA
Sequence: DDPTSTFTCPGGSDYK
What are the official names of this protein?
Thaumatin-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the thaumatin family.
What are the subcellular locations of this protein?
Secreted. Secreted, cell wall.
Protein: SDF2_DICDI
Sequence: MKSLFLILILCITIPLIFANESQYEDHPITKVTYGSMVKLAHVPTNFRLHSHKVSYGSSGGGSGQQSVTGFPENDDTNSLWVIKGPHGNRVLQGTVVKNGDIIRLVHSNTKKNLHSHLAVSPLTKQNEVSCFGENGEGDTGDNWIVETESGKEWMRGQVVRFKHADTKTYLQAIESAKYQNPIPGQIEISGGKSKNEDTKWRTEEGIYFDEK
What are the official names of this protein?
Stromal cell-derived factor 2-like protein, SDF2-like protein.
What are the subcellular locations of this protein?
Secreted.
Protein: RL1_SYNAS
Sequence: MSRRGKVYLNARGKVEAGRRYTLSEALALVTDTARAKFDETVEAAVRLGVNPAHADQMVRGSVVLPNGLGKTVRVLVFAKGEKEKEALDAGADYAGSDEFIEKIKSGWLEFDRVIATPDMMGNVGKLGKILGPRGLMPNPKVGTVTFDVATAVKEVKAGKVEFRVEKAGIVHSPVGKVSFGPDRLMENIQALIEMIIKLKPATSKGTYIKGIALSSTMGPGVRVDPLDLRNL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: PSBM_GOSHI
Sequence: MEVNILAFIATALFILVPTAFLLIIYVKTVSQSD
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface.
What are the official names of this protein?
Photosystem II reaction center protein M, PSII-M.
What is the protein family that this protein belongs to?
Belongs to the PsbM family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CCA_PSEA6
Sequence: MQVYLVGGAVRDKLLERPVKDKDWVVVGASEADMLAKGFQQVGKDFPVFLHPKTQQEYALARTERKIGQGYAGFECDTSTNVTLEQDLLRRDLTVNAMAMDDNGNIIDPFNGQKDLRNRVLRHVSDAFEEDPLRVLRVARFAARYASYGFSIADETKTLMANITQSGELSHLSAERVWVETAKSLLEDTPQIYFETLRECGALKVWFAELDCLWGIPNPAKWHPEIDTGIHSMMVLEQSVRVSHKLSVRFAALVHDLGKGLTPPEEWPSHRGHEKRGLVPINTLCERLKVPNDCRDLALLMSEFHSHVHHAFKLKAATINDFLDKCDVWRKPERFADLLLACTADAKGRTGFEERPYPNADYIWQAYLLAKEVNVQEIVQAGYKGAEIKQQLRQKRIHAIATNVA
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: PGK_ACIET
Sequence: MHILRFSDLCAQGQARGQRVFIRADLNVPQDDAGRITEDTRIRASVPCIQMALEAGAAVMVTSHLGRPTEGEFKPEDSLAPVAQRLSELLGREVPLVADWVDGVQVAPGQVVLLENCRVNKGEKKNNPELAKKMAQLCDIYVNDAFGTAHRAEGTTYGIAEYAKVACAGPLLAAEIDAIQTALANPKRPLVAIVAGSKVSTKLTILQSLSKNVDGLVVGGGIANTFMLAAGLPIGKSLAEPDLVNEAKAVIAAMAARGAEVPIPTDVVVAKAFAADAPATVKKASEVAEDDLILDIGPETAAKLAAQLKAAGTIVWNGPVGVFEFDQFAGGTKAIAQAIAESSAFSIAGGGDTLAAIAKYGIEKDVGYISTGGGAFLEVLEGKTLPAFEILQKRAAG
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGP_METTH
Sequence: MRAIAVDIDGTITDKKRRLSLEAVKALRGAEEAGVPVIMVTGNILCFAMATSVLIGASGGVVAENGGVLHINDEVRVLGDISKAEMAYSHLKGIYPVRKVQFSDLRVSEIALTRDVPADTVREALRDFDVEVYDTGFAIHLTDPSVNKGSSLEILLESMGIEMEDVMAIGDSENDLEFIEAAGFRVAVANADPELREMADYVTSAAHGEGVAEAVRRFMGW
What is the function of this protein?
Catalyzes the dephosphorylation of 2-phosphoglycolate.
What are the official names of this protein?
Phosphoglycolate phosphatase, PGP, PGPase.
What is the protein family that this protein belongs to?
Belongs to the archaeal SPP-like hydrolase family.
Protein: ST2A1_HUMAN
Sequence: MSDDFLWFEGIAFPTMGFRSETLRKVRDEFVIRDEDVIILTYPKSGTNWLAEILCLMHSKGDAKWIQSVPIWERSPWVESEIGYTALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLMRNPRDVLVSGYFFWKNMKFIKKPKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFLLLSYEELKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVDKAQLLRKGVSGDWKNHFTVAQAEDFDKLFQEKMADLPRELFPWE
What is the function of this protein?
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfonation of steroids and bile acids in the liver and adrenal glands.  Mediates the sulfation of a wide range of steroids and sterols, including pregnenolone, androsterone, DHEA, bile acids, cholesterol and as well many xenobiotics that contain alcohol and phenol functional groups (PubMed:7678732, PubMed:2268288, PubMed:14573603, PubMed:18042734, PubMed:19589875, PubMed:21187059, PubMed:29671343, PubMed:7854148).  Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites.  Plays an important role in maintening steroid and lipid homeostasis (PubMed:21187059, PubMed:19589875, PubMed:14573603).  Plays a key role in bile acid metabolism (PubMed:2268288).  In addition, catalyzes the metabolic activation of potent carcinogenic polycyclic arylmethanols (By similarity).
What are the official names of this protein?
Sulfotransferase 2A1, ST2A1, Bile salt sulfotransferase, Dehydroepiandrosterone sulfotransferase, DHEA-ST, DHEA-ST8, Hydroxysteroid Sulfotransferase, HST, ST2, SULT2A3.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 1 family.
What are the subcellular locations of this protein?
Cytoplasm.