PharMolix/UniProtQA huggingface dataset:
Protein: UBIE_STRM5
Sequence: MSESPYKSGTTHFGFRDVAAKDKQKLVGQVFTSVARNYDLMNDLMSMGVHRAWKRYYVATAQVKPGDRVLDLAGGTGDIAALLKERVGVEGSVVLGDINAGMLSVGRDRLTNRGLVLGLDYVQCNAEALPFPDNSFDLVTIAFGLRNVTDKDAGLREMYRVLKVGGQARVLEFSEVTADWFKPIYDFHSFKILPKLGKLFANDSDSYQYLAESIRKHPPQEELKAMMGQAGFERCHYKNLTGGIVSIHSGYKL
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: VATA_CAEBR
Sequence: MAAESSYGFVYGVSGPVVTAEKMAGSAMYELVRVGHQELVGEIIRLEGDYATIQVYEETSGVTIGDPVLRTGKPLSVELGPGIMGSIFDGIQRPLKDIADITQSIYIPKGVSTNALSREARWDFVVSKDLRVGGHVTGGDIVGTVDENLLIKHKILLPPSACGTVTFVAPSGQYTVEDTLLELEFAGRKQKFSMLQVWPVRNPRPVTEKLAANNPLLCGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNSDAIIYVGCGERGNEMSEVLRDFPELTMEVNGTTTSIMKRTALVANTSNMPVAAREASIYTGITLAEYFRDMGLNVAMMADSTSRWAEALREISGRLGEMPADSGYPAYLAARLASFYERAGRVKCLGSPEREGSVTIVGAVSPPGGDFADPVTSATLGIVQVFWGLDKKLAQRKHFPSINWLISYSKYMRALEEFYEKNYPEFVHLRTKCKEILQEEEDLSEIVQLVGKASLAESDKITLEVAKIIKDDFLQQNGYTPYDRFCPFYKTVGMLKNMIGFYDLARHSVEATAQSENKITWNVIKDNMGDLIYQLSAMKFKDPVADGEAKIRKDYDDLAEAMANGFRNLED
What is the function of this protein?
Catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).  Required along with other vacuolar ATPase components for the removal of protein aggregates which form in immature oocytes in the distal gonad.  This removal occurs as the oocytes mature and move to the proximal gonad, is triggered by the introduction of sperm through mating and occurs before fertilization.  The introduction of sperm triggers V-ATPase accumulation in proximal oocytes and induces lysosomal acidification which leads to engulfing of protein aggregates by lysosomes and subsequent clearance of the aggregates.  Lysosomal acidification also leads to changes in mitochondrial morphology and function.  Mitochondria in distal immature oocytes are fragmented, produce high levels of reactive oxygen species (ROS) and have high membrane potential, indicative of metabolic inactivity.  In contrast, mitochondria in proximal mature oocytes are tubular with lower ROS levels and membrane potential, indicative of an active metabolic state required for aggregate mobilization before clearance.  Involved in receptor-mediated endocytosis (By similarity).
What are the official names of this protein?
V-type proton ATPase catalytic subunit A, V-ATPase subunit A, V-ATPase 69 kDa subunit, Vacuolar H ATPase protein 13, Vacuolar proton pump subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: URED_ACIAD
Sequence: MNQPQDFPPQKSKALWYAQLELGFRFDGQRTIMNHRKHHGPVRVQKMLWPEKTGVCHAIIVHPPAGIAGGDHLTFQVSTERKAHAVVTTPGAGKWYKTNGKQAFQHIYLNIANDSTLEWLPQETMLFDAAYAQSETIIHLDQTASFMGWDMLVLGRQARLETFEQGCYANRFKLYRNHKLLVADTLRFKGKDRWLSSCLGMNGHAVMGSFWAVAPEKYRATLYLEQHIELIRELMMRMDVPVTLTLLDDVVCARFLGDDVRACHDAFAAIRARLRRYWFDLDEEFPRIWRT
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRS1_PICST
Sequence: MAAKDDLILTIDSDGDEIVYSEESEAEVEISVKKVKNKKNKKSKAQPQQKEEDEEKNEDINPNFIFSLDGIETTSKFDGWDFSVDRNANEVANKEVDLDGILRRKGGLVSLAGSDAQKEEEVEDEEEEENDEDIQNEDEDEGEEELALDGFGMGAEEKVIDEEDEEDEEDENDKSDGEDDKDTEVEVSEEGEEENDEDTAEAMAEFYADEKETKSAKSQVHTTFQTLQLSRPVLKGLSQLGYTKPSPIQSASIPIALLGRDIVAGAVTGSGKTAAYMIPIIERLLYKPSKVASTRVIVLTPTRELAIQVGDVGKKIGQFVNNLNFGLAVGGLNLRQQEQQLKSRPDVVIATPGRLIDHIRNSPSFSIDSLEVLVIDEADRMLDEGFQVELTEILSLIPKNKRQTLLFSATMNTKIQDLIQLSLQRPVRIMIDPPKTAATKLTQEFVRIRKRDHLKPALLFQLLKKLDPAQQSRIVVFVSRKESAHKLRIVLGLLGMKVSELHGSLTQEQRLNNVNDFKKLIVPVLICTDLAARGLDIPKIEIVINYDMPKSHEVYLHRVGRTARAGRDGTSISFVGESTSDRNIVKDAIKSLEGGEVKGKAVSRNIDWVDVEQLNKIVESKQEIIEEVLDEEKQAKEILQAEMQLAKASNMMKHEKEIQSRPKRTWFESEKDKKKHQTEVMQQLTKHGKKVNSKKRKAIEVKKDDGGRSYKKTKVDRITDQKRNPKAKIGNGSSKGGKRRK
What is the function of this protein?
ATP-binding RNA helicase involved in ribosome assembly.
What are the official names of this protein?
ATP-dependent RNA helicase DRS1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX27/DRS1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: Y902_LACE2
Sequence: MSGHSKFANIAHKKAANDAAKGKIFTRLGKELMIAVKEGGPDVNNNSKLRQVVAKCKAANMPNDTIDRAIKKAASNDMSNYESVTYEGYGPNGTAIIVEALTDNRNRAASNIRSAFTKGGGNVGTPGCVSFMFDNKGQMIVDKEEYTGDADELMMLALDAGADDFNEEEDCYEILTSPEEFDAVNQALADAGVTFASAEVTMIPQTTVDLTSEDDIKKMNRILGLLDEDDDVQNVYHNWNEPEEDEE
What are the official names of this protein?
Probable transcriptional regulatory protein EUBELI_00902.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTCA_PSEA7
Sequence: MGTLSVNQNKLQKRLRRLAGEAITDFNMIEDGDKVMVCLSGGKDSYTMLDILLYLQKVAPIRFEIVAVNMDQKQPGFPEHVLPEYLKSIGVEYHIVEKDTYSVVKEKIPEGKTTCSLCSRLRRGTLYTFADEIGATKMALGHHRDDILETFFLNMFYGGTLKAMPPKLLADDGRNVVIRPLAYCSEKDIEAYSQLKEFPIIPCNLCGSQENLQRQVVKEMLLEWERKSPGRTEIMFRALQNVVPSQLADRNLFDFASLRIDESATPRFLDVMNL
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WECG_SALPA
Sequence: MTNNAAAPLYSLRGLPLIGWRDMSHALNYLFADGQLKQGTLVAINAEKLLTAEDNPEVRALIGAAEFKYADGISVVRSIRKKFPQAQVSRVAGADLWEALMARAGKEGTPVFLVGGKPEVLAQTEAKLRTQWNVNIVGSQDGYFTPEQRQALFARIHASGAKIVTVAMGSPKQELLMRDCREVHPHALYMGVGGTYDVFTGHVKRAPKIWQNLGLEWLYRLLSQPKRITRQMRLLRYLRWHYTGDL
What is the function of this protein?
Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis.
What are the official names of this protein?
UDP-N-acetyl-D-mannosaminuronic acid transferase, UDP-ManNAcA transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 26 family.
Protein: RPPH_RHOP5
Sequence: MARYEDLPYRTCVGMMLLNAEGLVFIGRRSGGIEHVDDSHVWQMPQGGVDPGEDTWAAAKRELYEETSVQSVEKLGEISDWLIYDIPRTVAGRAWKGRYRGQRQKWYAVRFTGLDSEIDVTTPGGGHKAEFISWRWEPMQNLPNLIVPFKRPVYERVVKEFSALGFPEPKASVGHR
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: OCA5_CANDC
Sequence: MFQSSKGSNSSSTSSSRSASISTATPNTVVEDEELLCDPKSELTPPAVTTPLRPVSKSNNTVEDDSKPSFTYDLDVFNLCKEYLNTRNHHGLALIARQKGIPPILRFKVWPILLKSHPFVISPFIQPDSELINESTSSRSNSSSSSTSTGSTTPISTSSGNIKDAAIIDGGASDNDNDGNNDNNDKDNNSNDTSSKEKEEDEQNNEIRQKIKRDLAKYIQRLKYSQSKYTVGETEHEILSILENAIMKFTLKWGKIIKYDSSLTWIALNLAEWFPPIPKTPWVLVGKEYSSSHQSLIVNFLDDYSNYIDNIPDLREYLERLIYHDERISTISFREVYERLVLVLLHCPQPMSRRKKSDNQGQSQRRNQSEAQKDQQSFKVNKTTLPKTGGTIEERVSYFIYCLRKLIPELSQYFHEEQILTKFGCLDDEWLIWWLKFCGTKVWSKYDRGRIWDFMLGWRLKNPKRDFNYYYEKLNYVNRNTLEKLGPDIFWSVGNEEDDISGDKNVDANANEINNSEKTSTGKLVKREGDIKRSSFKDLVNELSNELHISKRVSTDGVITSSSSSSSPTTTKLAPSSSTSSTITPNVSIPFSRVDPHVALIFISLSLLKSKENILVELDQHEIRQFLSRLPSKSYKYNQKRTTKPKRTSYTSNASSTSNSPMGQSPVDRDEDSIFPTNRIVISNDSKDQKHKVNFIDNIIQEAGELWRKWLWSEMVEDN
What are the official names of this protein?
Oxidant-induced cell-cycle arrest protein 5.
What is the protein family that this protein belongs to?
Belongs to the OCA5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF3_AZOC5
Sequence: MRPVAPEKDGPRVNEEIRIREVQLIDQDGQNRGVLPTRDALLLAQEAGLDLVEISPNSSPPVCKILDFGRFKYQNQKKASEARKKQKVVEVKEIKLRPGIDTHDYDVKMKAMLRFFEEGDKVKVTLRFRGREMAHQDIGYKLLQKLKEDVTNIAKVEAEPMLEGRQMIMILAPR
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPB2_FRG3G
Sequence: MSRGMTTEGASLTAAASSSASTWLTESTPSTPSSSGSSYPALSTFSSCSNSASSPDEADPMSEMSPKISVASMILLKDMEEFLHLYVSSANMHPSNFVRHHIESFDDMLWNEFPAMVAREKPVSVKGYRVKFGTVRYEPPCPDGKPWEKLTPAMARRTDATYHSAAVCDLTVTDPKGLETVYPRLELCKIPVMVGSAVCWTRTEGSPLPGECPSDPGGYFIIKGKERVVVPHIRPAYDQPCVYKNGDGWLCEFRSVNRETRQTVLVQAKTDCRRKLEFSLPYIKQYVPVGLVFKALGKTAREAVAMCGLGSFLGDEVSCRTVHHQSMAALLMEQHASAPEDPVADLAKHVPDGRSVYSKQAEGAKQAKYADRASVEEDRNAKGSKEDYVRHVLAGEIFLHGGDAAEHLGWMVKRMADAASGIGTCTDRDDLANKRVDATGPLIAFLLDGLLKQYVKLFVKSAGCQKNLCPYTVLQNSMVMTNSLHMCFATGNWTVKRLGPPSYVRVGVSQVLSNNNYGARVSHLRRIMHAVSFRGKNIRMRQLHSSHYGFLCPYETPEGEKVGIVLNMAEGAGFSLETPREVVLATVRLGKGLPGFFEGAPARLAWSGAAGSASVDVDGVLCGVTGDPVGFVREARLCLPGVSVVWKKVEREIHLLGCQGRFVRRVLDPEGIRGSGYDSPPAPEERDIEMDPAPSSSPSDSLPCPPGVYVCAQELSVCSLGDGEYADPPASEILTDAMSSVIPFYDHTQSPRNAYQSNMGKQAIGFPAVNCSDRYDATLHRLDYPQKSLVDSRSVKRLGFDEMAHGALPVVAIMTAGGFNQEDSVVLNASSLDRGLFSCVTYRTVSCADKRRTKYDSEVVCLPDWGLRNREWDYDLLGDDGVIDPSCAGALARRVEGKRKAAKRPAGQRTGGGPAGLCDALWIPAGTVLVGKVSHSLGPGGNPMRRDVSLTVKQSEEGYLDRVTVDVDSDGKKLVKVRLRTPRHPEMGDKFASFTAQKGTCGAVLTQEDMPFDKDGVVPDLIINPHAFPSRMTVNYLLQMCFGTAACKLGKTYDATAFEREDVVRDIAEAAKEAGIDCWDSVLHSGSTGRRLPTKIFMAPCPYQRLKHMVSGKMHSRTHGPTDALTRQPVAGRSREGGIKIGEMEQWCKISHGASESLKESVYDMSDKYEVPVCKECGRISDHFEYCRMCDATDMSLVKLPYTTKILFQELRSIGISIAFK
What is the function of this protein?
Component of the DNA-dependent RNA polymerase that catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Second largest component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs.  Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit (By similarity).
What are the official names of this protein?
Putative DNA-directed RNA polymerase II subunit RPB2 homolog.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: RSMH_LAWIP
Sequence: MHQPVMLEETIAMLKPHAKGRYLDGTVGLGGHSFAILQSAGDGAELCGLDQDKKALAIAEMTLKPFKKRVHLVHTKYSSFPLILKALGWKLLDGALIDIGVSSLQLDNAERGFSFLYDGPLDMRMDQDANNNSLFEIVNKSRQEYLKDIISRYGEEPQANRIAKAIVQKRRTKPITTTKELADLIEQAYPAAWRAKSRHHPATKTFQAFRIVVNSELNELEKFLNMIMGWIAPGGRVAVISFHSLEDRIVKQYMKSWTRSCICPPYVPVCKCFHKPEAILITKKPIRPSEKEISENIRSRSAKLRVAEKVLL
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1923_ACIBS
Sequence: MHCDIYRSSKKDEMYIYIARPNYPDETEQADPFEKVPEAVLQAFGRATFVMHLELAPTRKLARVNVLHVLDSLQTKGFFIQMPPEGLINPNAVEPEGLRGA
What are the official names of this protein?
YcgL domain-containing protein ABSDF1923.
Protein: MSP1_YEAST
Sequence: MSRKFDLKTITDLSVLVGTGISLYYLVSRLLNDVESGPLSGKSRESKAKQSLQWEKLVKRSPALAEVTLDAYERTILSSIVTPDEINITFQDIGGLDPLISDLHESVIYPLMMPEVYSNSPLLQAPSGVLLYGPPGCGKTMLAKALAKESGANFISIRMSSIMDKWYGESNKIVDAMFSLANKLQPCIIFIDEIDSFLRERSSTDHEVTATLKAEFMTLWDGLLNNGRVMIIGATNRINDIDDAFLRRLPKRFLVSLPGSDQRYKILSVLLKDTKLDEDEFDLQLIADNTKGFSGSDLKELCREAALDAAKEYIKQKRQLIDSGTIDVNDTSSLKIRPLKTKDFTKKLRMDATSTLSSQPLD
What is the function of this protein?
Outer mitochondrial translocase required to remove mislocalized tail-anchored transmembrane proteins on mitochondria (PubMed:24843043, PubMed:24821790, PubMed:28906250, PubMed:30858337, PubMed:31445887, PubMed:28712723).  Specifically recognizes and binds exposed hydrophobic surfaces of mistargeted tail-anchored transmembrane proteins (PubMed:30858337).  Acts as a dislocase that mediates the ATP-dependent extraction of mistargeted tail-anchored transmembrane proteins from the mitochondrion outer membrane (PubMed:24843043, PubMed:24821790, PubMed:28906250, PubMed:30858337, PubMed:32541053, PubMed:28712723).  Able to unfold protein substrates by processive threading through its central pore (PubMed:32541053).  Once extracted from the mitochondrion outer membrane, substrate proteins are then transferred to the endoplasmic reticulum, where they are ubiquitinated and degraded by the proteasome (PubMed:31445887).  Also mediates extraction of excess tail-anchored proteins from the peroxisomal membrane (PubMed:28906250).  In normal conditions, MSP1 translocase activity is inhibited by PEX3 at peroxisomes; only catalyzes removal of excess tail-anchored proteins (PubMed:28906250).
What are the official names of this protein?
Outer mitochondrial transmembrane helix translocase, Mitochondrial sorting of proteins, Tat-binding homolog 4.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. MSP1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein. Peroxisome membrane; Single-pass membrane protein.
Protein: YCF2_SOLLC
Sequence: MRGHQFKSWIFELREILREIKNSHHFLDSWTQFNSVGSFIHIFFHQERFLKLFDPRIWSILLSRNSQGSPSNRYFTIKGVILFVVAVLIYRINNRNMVERKNLYLIGLLPIPMNSIGPRNDTLEESVGSSNINRLIVSLLYLPKGKKISESCFLNPKESTWVLPITKKCSMPESNWGSRWWRNWIGKKRDSSCKISNETVAGIEILFKEKDLKYLEFLFVYYMDDPIRKDHDWELFDRLSLRKSRNRINLNSGPLFEILVKHWISYLMSAFREKIPIEVEGFFKQQGAGSTIQSNDIEHVSHLFSRNKWAISLQNCAQFHMWQFRQDLFVSWGKNPPESDFLRNVSRENWIWLDNVWLVNKDRFFSKVQNVSSNIQYDSTRSSFVQVTDSSQLKGSSDQSRDHLDSISNEDSEYHTLINQREIQQRKERSILWDPSFLQTERKEIESGRFPKCLSGYSSMSRLFTEREKQMINHLFPEEIEEFLGNPTRSVRSFFSDRWSELHLGSNPTERSTRDQKLLKKQQDLSFVPSRRSEKKEMVNIFKIITYLQNTVSIHPISSDPGCDMVPKDEPDMDSSNKISFLNKNPFFDLFHLFHDRNRGGYTLHYDFASEERFQEMADLFTLSITEPDLVYHKGFAFSIDSCGLDQKQFLNEARDESKKKSLLVLPPIFYEENESFSRRIRKKWVRISCGNDLEDPKPKIVVFASNNIMEAVTQYRLIRNLIQIQYSTYGYIRNVLNRFFLMNRSDRNFEYGIQRDQIGKDTLNHRTIMKYTINQYLSNLKKSQKKWFEPLILISRTERSMNRDPDAYRYKWSNGSKSFQEHLEQSVSKQKSRFQVVFDRLRINQYSIDWSEVIDKKDLSKSLRFFLSKSLLFLSKLLLFLSNSLPFFCVSFGNIPIHRSEIYIYEELKGPNDQLCNQLLESIGLQIVHLKKLKPFLLDDHDTSQKSKFLINGGTISPFLFNKIPKWMIDSFHTRNNRRKSFDNPDSYFSMIFHDQDNWLNPVKPFHRSSLISSFYKANRLRFLNNPHHFCFYWNTRFPFSVEKARINNSDFTYGQFLNILFIRNKIFSLCVGKKKHAFWGRDTISPIESQVSNIFIPNDFPQSGDETYNLYKSFHFPSRSDPFVRRAIYSIADISGTPLTEGQIVNFERTYCQPLSDMNLSDSEGKNLHQYLNFNSNMGLIHTPCSEKDLSSEKRKKWSLCLKKCVEKGQTYRTFQRDSAFSTLSKWNLFQTYMPWFLTSTGYKYLNLIFLDTFSDLLPILSSSQKFVSIFPDIMHGSGISWRILQKKLCLPQWNLISEISSKCLHNLLLSEEMIHRNNESPLISTHLRSPNAREFLYSILFLLLVAGYLVRTHLLFVSRASSELQTEFERVKSLMTPSSMIELRKLLDRYPTSEPNSFWLKNLFLVALEQLGDSLEEIRGSASGGNMLGPAYGVKSIRSKKKDWNINLIEIIDLIPNPINRITFSRNTRHLSHTSKEIYSLIRKRKNVNGDWIDEKIESWVANSDSIDDEEREFLVQFSTLTTENRIDQILLSLTHSDHLSKNDSGYQMIEQPGAIYLRYLVDIHKKHLMNYEFNPSCLAERRIFLAHYQTITYSQTSCGENSFHFPSHGKPFSLRLALSPSRGILVIGSIGTGRSYLVKYLATNSYVPFITVFLNKFLDNKSKGFLLDEIDIDDSDDIDDSDNLDASDDIDRDLDTELELLTRMNGLTVDMMPEIDRFYITLQFELAKAMSPCIIWIPNIHDLDVNESNDLSLGLLVNHLSRDCERCSTRNILVIASTHIPQKVDPALIAPNKLNTCIKIRRLLIPQQRKHFFTLSYTRGFHLEKKMFHTNGFGSITMGSNARDLVALTNEVLSISITQKKSIIDTNTIRSALHRQTWDLRSQVRSVQDHGILFYQIGRAVAQNVLLSNCPIDPISIYMKKKSCNEGDSYLYKWYFELGTSMKRLTILLYLLSCSAGSVAQDLWSLSVPDEKNGITSYGLVENDSDLVHGLLEVEGALVGSSRTEKDCSQFDNDRVTLLLRPEPRNPLDMMQKGSWSILDQRFLYEKYESEFEEGEGEGALDPQEDLFNHIVWAPRIWRPWGFLFDCIERPNELGFPYWSRSFRGKRIIYDEEDELQENDSGFLQSGTMQYQTRDRSQGLFRISQFIWDPADPLFFLFKDQPPGSVFSHRELFADEEMSKGLLTSQTDPPTSLYKRWFIKNTQEKHFELLINRQRWLRTNSSLSNGSFRSNTLSESYQYLSNLFLSNGTLLDQMPKTLLRKRWLFPDEMKIGFM
What is the function of this protein?
Probable ATPase of unknown function.  Its presence in a non-photosynthetic plant (Epifagus virginiana) and experiments in tobacco indicate that it has an essential function which is probably not related to photosynthesis.
What are the official names of this protein?
Protein Ycf2.
What is the protein family that this protein belongs to?
Belongs to the Ycf2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma. Plastid, chromoplast stroma.
Protein: NAGK_VIBPA
Sequence: MYYGFDVGGTKIEFGAFNEKLERVATERVPTPTDNYELLVDTIAELVNKYDAEFGCEGTIGLGLPGMEDADDATVLTVNVPAAKGKPLRADLEAKIGRSVKIENDANCFALSEAWDEELQDEPSVLGLILGTGFGGGFIYDGKVFSGRNHVAGEVGHTRLPIDAWFHLGENAPLLGCGCDKKGCLDSYLSGRGFELLYAHYYGEEKKAIDIIKAHAEGEAKAVEHVERFMELLAICFANIFTATDPHVVVLGGGLSNFELIYEEMPKRIPKYLLSVAKCPKIIKAKHGDSGGVRGAAFLHIK
What is the function of this protein?
Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.
What are the official names of this protein?
N-acetyl-D-glucosamine kinase, GlcNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family. NagK subfamily.
Protein: CYAA_SALTI
Sequence: MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPSGICFYTPDETQRHYLNELELYRGMTPQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCHQSWLDGEERQLLQRKCSLLESWAASLGVEVSFFLIDENRFRHNESGSLGGEDCGSTQHILLLDEFYRTAVRLAGKRILWSMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLDPYCMMLERVTEYLTAIEDPTRLDLVRRCFYLKVCEKLSRERACVGWRREVLSQLVSEWGWDDARLTMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRFARRNNLSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIHVPPGRANRSGWYLYNRAPNMDSIISHQPLEYNRYLNKLVAWAWFNGLLTSRTHLFIKGNGIVDLPKLQEMVADVSHHFPLRLPAPTPKALYSPCEIRHLAIIVNLEYDPTAAFRNKVVHFDFRKLDVFSFGEEQNCLIGSIDLLYRNSWNEVRTLHFNGEQAMIEALKTILGKMHQDAAPPDSVEVFCYSQHLRGLIRTRVQQLVSECIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGAISHNKLHGLSVQVETNQVKLPSVVDGFASEGIIQFFFEETGDEKGFNIYILDESNRAEVYHHCEGSKEELVRDVSRFYSSSHDRFTYGSSFINFNLPQFYQIVKTDGRAQVIPFRTQPINTVPPANQDHDAPLLQQYFS
What are the official names of this protein?
Adenylate cyclase, ATP pyrophosphate-lyase, Adenylyl cyclase.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14_PARXL
Sequence: MAKLALIEREKKRARLAAKYAPKRAELKAIIGDMSKSDEEHYAARLELQQLPRNSNPTRKRNRCAITGRPRGTFRKFGLARNKIREIAFRGEIPGLTKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: GLB5_PETMA
Sequence: MPIVDTGSVAPLSAAEKTKIRSAWAPVYSTYETSGVDILVKFFTSTPAAQEFFPKFKGLTTADQLKKSADVRWHAERIINAVNDAVASMDDTEKMSMKLRDLSGKHAKSFQVDPQYFKVLAAVIADTVAAGDAGFEKLMSMICILLRSAY
What are the official names of this protein?
Globin-5, Hemoglobin V.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: KGUA_RHIEC
Sequence: MKPAKSSPVQIARRGLMLVISSPSGAGKSTIARTLLETDKHIGLSVSVTTRPRRPSEVEGVHYHFKSVREFERLRDSDALLEWAEVHGNFYGTPREPVEQAMAEGRDMLFDIDWQGAQQLQEKMSADVVSIFVLPPTMTELQSRLHRRAEDSEEVIQTRLANSRAEIAHWREYDYVIVNDDLNTAFDAVQSIVKAERLRRDRRHGMFDFVRELLEETPSL
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TASC_HAPIR
Sequence: MTVSNKTQTALVGSPDGAIILSDTAPLPPSQLEDEQVAVAVQAVSLNPVDTKMAGDYHTPGAISGCEFAGVVTAVGPGAASEWGLGPGDRVSAAIMGMNPLRPSIGAFAQHSVAPAHCLLKMRDDWGFAQAAGLGNSWYTVAWALFHVMGLPAGPELEPLHTKHPPPAREPRISIDNPAPNGGGGKRTTVLVSGGSSSTGTCAIQLLKLAGFDVVATSSARNFDLVRSYGADAVFDHSSPSVAADIKAHTRNGLRLALDCITTPDTTRLCYGAIGRTGGRYVSLDPYSEVVAASRAVVRADWVLGPELMGEDVGWPAPHGRKGNPEAKAFCKVWNRTLQGLLDRGAIRTHPQRVRDTGLRGVLEGLDDIREKRVSGEKLVYTLQV
What is the function of this protein?
Trans-enoyl reductase; part of the gene cluster that mediates the biosynthesis of the tetramic acids Sch210971 and Sch210972, potential anti-HIV fungal natural product that contain a decalin core (PubMed:25885659).  The PKS module of tasS together with the enoylreductase tasC catalyze the formation of the polyketide unit which is then conjugated to 4-hydroxyl-4-methyl glutamate (HMG) by the condensation domain of the tasS NRPS module (PubMed:25885659).  One unique structural feature of Sch210971 and Sch210972 is the tetramic acid motif proposed to be derived from the non-proteinogenic amino acid HMG, by a Dieckmann-type condensation catalyzed by the reductase domain of tasS (PubMed:25885659).  The aldolase tasA catalyzes the aldol condensation of 2 molecules of pyruvic acid to yield the intermediate 4-hydroxyl-4-methyl-2-oxoglutarate (HMOG), which can then be stereoselectively transaminated, may be by tasG, to form HMG (PubMed:25885659).  The Diels-Alderase tas3 then uses the Dieckmann product of tasS as substrate and catalyzes the Diels-Alder cycloaddition to form the decalin ring of Sch210971 and Sch210972 (PubMed:25885659).
What are the official names of this protein?
Trans-enoyl reductase tasC, ER tasC, Tetramic acid Sch210971/2 biosynthesis cluster protein C.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: SYG_BORAP
Sequence: MVRMEDIISLAKRKGFVFQSSEVYGGLSGVWDYGPLGIELKENIKREWWKSMVYLHENIVGLDSAIFMRSEIWKASGHIDGFSDSMVDCKDCKSRFRADFVDLSKNCPNCKVGNNFTSPRNFNLMFKTHIGVVEDSSSEIYLRPETAQGIFVNFRNVLDSSRLKIPFGIAQVGKAFRNEIVAKNFIFRTCEFEQMEMQFFVHPKQIDEWFCYWQQNRMNFFIETLKIRPDRLRLKAHNSTELAHYAKSAFDIEYEFPFGFQEIEGIHNRGNYDLTQHSKFSNNSKVFEYHDLLTKERYVPYVIETSAGLTRSVLMTLCDAYSEEELSDGDKRIVLRLHPKLAPYKIAIFPLVKKVELVEVARRIYVELCDDFHIFYDDSGTIGKRYRRQDEIGTPYCVTVDYNTIEDETVTVRERNNMTQKRIFINDLYSYIKTEILNYKEDVNK
What is the function of this protein?
Catalyzes the attachment of glycine to tRNA(Gly).
What are the official names of this protein?
Glycine--tRNA ligase, Glycyl-tRNA synthetase, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.