PharMolix/UniProtQA huggingface dataset:
Protein: RPOZ_COXB2
Sequence: MARVTVEDCLEHVENRFDLVLKAAKRAHILELGGAEPMVPRDNDKPAVLALREIAAGYDVTREGQEQETEEVDVDRNVLAETAKMNKAVASQKESEV
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: MURC_MOOTA
Sequence: MADLETGGWTHFVGIGGVGMSALARILLAQGYRVSGSDPKENQFTRSLEAAGAIIYHQHDAANLAPGVQEVVISSAVPSSNPEVVAARQRSLPVVKRGELLARLFNARRGIAVAGAHGKTTTSALVALVMKEGGLEPAAVIGGYVREFASNAYPGRGDFLVAEADESDGSFLWLKPEIALITNIEADHLEHYGSLDRIVAAFKDFIDQIRPGGKAILCAEDPRVAGLVACSPRQVITYGLNGRPDYRATGVQMAGMGGRAAIYYREQYLGQLTMAVPGRHNILNALGAIAAGHQLGIPFAVMARALGQFRGVGRRFEILWDDGTTRVVDDYAHHPTEIRATLAAASQVGAKRVVAVFQPHRYTRTHHLYREFGQAFRQADVVIVNDIYPAGEAPLPGVNSQLITGEIKGSGHQQVYYLPTLEETLAFLKKSCRPGDLVLTLGAGDVWRVGMGLAQYLEAKQILPGVGA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDL_BACP2
Sequence: MKISLGLIYGGKSAEHNVSLQTALAVTKALNTEKFDIHPIYITEEGEWLRGEKLTEPVSNVRMLQFEQNAKTFLPTSLNESMFPQPTSADEKIDVVFPLLHGPNGEDGTMQGLLELLNIPYVGNGVLASAAGMDKVMMKDVFAQAGLAQAKHLSFNKKDYEKATPDSLEQVEQVLGYPCFVKPANMGSSVGISKCRSKEELQTAFDLAFQYDRRVVVEEGVVGREIEIGVLGNDEPKCSVVGEIAPKTDFYDYKAKYEDGDTDLIIPASVSEDEYKTIHDMAIKAFKSLDGSGLVRADFFLTEKGEVLINEVNTMPGFTPFSMFPLLWKHTGVEYPELIEKLVSLAIERHQEKQTIKTTF
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF15_SOLBU
Sequence: METLVSSIFWTLAPWKNMLLLKHGRIEILDQNTMYGWYELPKQEFLNSKQPVQIFTTKKYWILFRIGPERRRKAGMPTGVYYIEFTR
What are the official names of this protein?
Putative uncharacterized protein ycf15.
What is the protein family that this protein belongs to?
Belongs to the ycf15 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RBL2_MAGSA
Sequence: MDQSKRYVNLGLREADLIKGGRHVLCAYRMRPRPGHGYVETAAHFAAESSTGTNVEVCTTDDFTRGVDALVYEVDEAEGLMKIAYPVELFDRNIIDGKAMIASFLTLTVGNNQGMSDVENAKMEDFYVPPDFLTLFDGPARNIAHMWKVLGRPEVNGGMVVGTIIKPKLGLRPKPFADACHQFWLGGDFIKNDEPQGNQVFAPFKDTMRLVADSMRRAQDETGQAKLFSANITADDPAEMIARGQFILDTFGENASHVAFLVDGFVAGPTAVTTCRRNFPDTFLHYHRAGHGAITSRQSKRGYSVLVHMKMARLLGASGIHTGTMGYGKMEGAPDEKVVAYMLERPTAEGPHYRQDWGDMRACTPIISGGMNALRLPGFFDNLGHSNVIQTSGGGAFGHKDGPVAGALSLRQAHEAWMRGISLVEYAQGHPELRGAFESFASDADRLYPGWRDRLRIAA
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase, RuBisCO.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type II subfamily.
Protein: RL27_KORVE
Sequence: MAHKKGLGSSRNGRDSNAQRLGVKAFGGETVTGGTIIVRQRGTRIKPGLNVGRGKDDTLFAKADGRVEFKDRGNLGRFVSIVPAKA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: RL5_FRASN
Sequence: MSVTTEARPVPRLKQRYREEIAPALREEFSYGNVMQIPGVVKVVVNMGVGDAARDAKLIDGATRDLAAITGQKPAVRRAKKSIAQFKLREGQPIGAKVTLRGDRMWEFLDRLVTIALPRIRDFRGLSPKQFDGAGNYTFGVIEQSIFHEIDIDRIDRVRGMDITVVTTATNDDEGRALLRALGFPFRES
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: R9BPB_XENLA
Sequence: MPLQNVKVADEGSVNFQKVKEECITAMESLHKVVACYRHLALTIGGSSDSIHLRDELRRTRERAQELALSNRNKLTTALRDKKLSKKDREELERLWVEFSSCLELFHNDMCKVYELGMAVPHSATNKPAIQTGSTGNTSAIASRALNVQNINYSDSPANKASLEYQEIEEEILKVDNMITDMEMKVNVLRWTVEANTRMNDELKSTHDSSSVVLLSEEESNSKGCCSDGQLIVFLLLCGTALVAITLYSIL
What is the function of this protein?
Regulator of G protein-coupled receptor (GPCR) signaling.  Probably acts by regulating the activity of some 'R7' family protein (RGS6, RGS7, RGS9 and/or RGS11).
What are the official names of this protein?
Regulator of G-protein signaling 9-binding protein B, RGS9-anchoring protein B.
What is the protein family that this protein belongs to?
Belongs to the RGS7BP/RGS9BP family.
What are the subcellular locations of this protein?
Membrane; Single-pass type IV membrane protein.
Protein: GOS1_SCHPO
Sequence: MKSMLLRDSVKKASQFQRSLHSDPNQAKILLEERRKLLEEANSSADENDSHSMATIKSHFERLKRDEQLLNGVLKKYDAKQEVLSPEELRDAQNFLEMQEANSLDNSIRGTNELLERAYATREDFDYQNSVLGNVTNRINGAAMSIPFINQILRKTSIRRRRDSIILALLISVLMLLFLFFH
What is the function of this protein?
Nonessential SNARE involved in retrograde transport within the Golgi complex.
What are the official names of this protein?
Protein transport protein gos1, Golgi SNAP receptor complex member 1, Golgi SNARE protein 1.
What is the protein family that this protein belongs to?
Belongs to the GOSR1 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type IV membrane protein.
Protein: CERS_CAUVN
Sequence: MPFDSTNADLSVIPVKTPAELKRFIALPARLNAKDPNWITPLFMERTDALTPKTNPFFDHAEVQLFLATRGGRDVGRISAQIDQLTPQPTEGRLDGHFGMIAAEDDPAVFNVLFRAAEDWLRARGRTHAVGPFNLSINEEVGLLVWGFDTPPMVLMGHDPVYAGPRVEEQGYAKAQDLFAYKADETGDIPEIAQRRVKRGLPSGVVLRQLDMSRYDQEVQTLTEILNDAWSDNWGFTPTTEAETRQLAKSLKQVIDQRLVWFSEIDGEAAGVVVFLPNVNEAIADLKGKLLPFGWAKLLWRLKVKGVKSARIPLMGVKKKFQTSQRGRMLPFWMMKASRDMAMSLGYNRYEISWVLEANKAMTHIAENVGGTHYKTYRVYEKAL
What is the function of this protein?
Involved in de novo bacterial ceramide synthesis (PubMed:33063925, PubMed:34969973).  Catalyzes the condensation of 3-oxosphinganine with an acyl-CoA to generate oxidized ceramides (PubMed:34969973).  Can use acyl-CoA substrates ranging from C8 to C24, with highest in vitro activity with C14 and very little activity with acyl-CoA thioesters of 18 carbons or longer (PubMed:34969973).  May have a preference for monounsaturated acyl-CoA substrates, as it has a threefold greater preference for C16:1-CoA over C16:0-CoA as a substrate in vitro (PubMed:34969973).
What are the official names of this protein?
Bacterial ceramide synthase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YHBF_BACSU
Sequence: METTKLGNLKLYGAGHAAGGAYHNVSIKGEGIVGEGLSAVGCRIYGTGLFLGKAETERLRVLGESECKGDLTAGKINIYGTMKVSGSLQFDRFNLKGQTEIGGNMTGESCDVKGKLSVIGDCETEMFHVTGCVDVSGLLNSGEIKLGLSHDISHVQEIGGTTITVKRRASFFSRKKGKLIADVIEGDRVYLENTEAAVVRGKEVIIGPGCSIGTIEYEYKCECDPHSQIKEKTKL
What are the official names of this protein?
Uncharacterized protein YhbF.
Protein: HA18_MOUSE
Sequence: MALTMLLLLVAAALTLIETRAGPHSLRYFHTAVSWPGLVEPRFIIVGYVDDTQFVRFDSDAENPRMEPRARWMEQEGPEYWERETQKAKGHEESFRVSLRTAQRYYNQSKGGSHTLQWMYGCDVGSDERLLRGYLQFAYEGRDYIALNEDLKTWTAADMAAQITLHKWEQAGIAERDRAYLEGACVQSLRRYLQLRKETLLCTDPPKAHVTHHPRSYGAVTLRCWALGFYPADITLTWQLNGEELTQDMELVETRPAGDGTFQKWASVVVPLGKEQNYTCHVNHEGLPEPLTLRWEPPPSTVSNMANVAILVVLVAWPSLELWWIL
What is the function of this protein?
Involved in the presentation of foreign antigens to the immune system.
What are the official names of this protein?
H-2 class I histocompatibility antigen, Q8 alpha chain.
What is the protein family that this protein belongs to?
Belongs to the MHC class I family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RBSA_DEIGD
Sequence: MLALQHASKSFGPVRALSDVSLELYSGEAHALLGENGAGKSTLVKILSGVHRADGGELWVDGQLRVFHSPAEARDAGIAIIYQEPTLFPDLTVAENVLMGRQPLRRGRIDRRAMLTHVGRILQELGVPLDPARPVRGLSIADQQLVEIAKALSFQARVLIMDEPTAALTGQETERLFRVVRTLRARGAAVLLITHRLEEAFAECQRFTIMRDGRWVSSGPAAAYTIDSVVRGMVGRDVRELYPKLPVTPGEVALEVRGLSRRGVFRDVSFVVRRGEIVGLAGLVGAGRSEVARSIFGIDPRDAGEVRVQGRTIPAGNTQAAMRAGIGLVPEDRRQQGLVMDLSIERNATLTVLNRLRRGWLMDRTAETQTASDWTSRLRLKAHRLTDPVSTLSGGNQQKVVLAKWLATGPAVLIVDEPTRGVDVGAKAEVHRTLAELAAGGLAVVMISSDLPEVLGMADRILVMREGALVGELSRQDASEEAVMYLATGQQPAIGSVA
What is the function of this protein?
Part of the ABC transporter complex RbsABC involved in ribose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Ribose import ATP-binding protein RbsA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RHAT_ECO8A
Sequence: MSNAITMGIFWHLIGAASAACFYAPFKKVKKWSWETMWSVGGIVSWIILPWAISALLLPNFWAYYSSFSLSTLLPVFLFGAMWGIGNINYGLTMRYLGMSMGIGIAIGITLIVGTLMTPIINGNFDVLINTEGGRMTLLGVLVALIGVGIVTRAGQLKERKMGIKAEEFNLKKGLVLAVMCGIFSAGMSFAMNAAKPMHEAAAALGVDPLYVALPSYVIIMGGGAIINLGFCFIRLAKVKDLSLKADFSLAKPLITHNVLLSALGGLMWYLQFFFYAWGHARIPAQYDYISWMLHMSFYVLCGGIVGLVLKEWNNAGRRPVTVLSLGCVVIIVAANIVGIGMAN
What is the function of this protein?
Uptake of L-rhamnose across the cytoplasmic membrane with the concomitant transport of protons into the cell (symport system).
What are the official names of this protein?
L-rhamnose-proton symporter, L-rhamnose-H(+) transport protein.
What is the protein family that this protein belongs to?
Belongs to the L-rhamnose transporter (TC 2.A.7.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL16_CALS8
Sequence: MLMPKRVKYRKQQRGRMKGKATRGNFVAYGDFGIMALEPGWITSNQIEAARVAIARHIKRGGKVWIKIFPDKPVTRKPAETRMGSGKGSPEYWVAVVKPGRVMFEVGGVDKEVAKEALRLAIHKLPIKCKIVSRQDVEMGGEVNEGV
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: DUT_ACTSZ
Sequence: MKKIDVKILDSRIGAQFPLPAYATTGSAGLDLRALTDEAFEIQPGETKLIPTGLSVYIADPQLAAVILPRSGLGHKHGVVLGNLVGLIDSDYQGPLMVSMWNRSDKPFKVEVGDRIAQLVFVPVVQAEFNIVAEFEQTDRGEGGFGHSGKK
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: ZDH12_MOUSE
Sequence: MALWPPLNSGMLVRTGHTVLTWGITLVLFLHDTELRQWEEQGELLLPLTFLLLVLSSLLLYLAVSLMDPGYVTTQPQPQGEPKEEQAAMVPQAVPLRRCRHCLVLQPLRARHCRDCRRCVRRYDHHCPWMENCVGERNHPLFVAYLALQLVVLLWGLCLAWSGLQFFQPWGLWLRSTGLLFTTFLLLSFFALVVALLLASHLYLVARNTTTWEFISSHRIAYLRQRTSNPFDRGPTRNLAHFFCGWPSGPWETLSAEEEEEGSSQVV
What is the function of this protein?
Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates (PubMed:25025157).  Has a palmitoyltransferase activity toward gephyrin/GPHN, regulating its clustering at synapses and its function in gamma-aminobutyric acid receptor clustering (PubMed:25025157).  Thereby, indirectly regulates GABAergic synaptic transmission (PubMed:25025157).  Acts as an inhibitor of the NLRP3 inflammasome by mediating palmitoylation of NLRP3, thereby promoting NLRP3 degradation by the chaperone-mediated autophagy (CMA) process (PubMed:36586411).
What are the official names of this protein?
Palmitoyltransferase ZDHHC12, DHHC domain-containing cysteine-rich protein 12, DHHC-12, Zinc finger DHHC domain-containing protein 12.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: TRPA_LEGPC
Sequence: MNRIDKTLEKLKANRKKMLSPYITAGDPYPELTVSLMHQLVKSGADVLELGIPFSDPMAEGPVIQRAMERALAHSIHCDDVLNMVRQFRKTDNETPVILMGYLNPIEQYGYDLFAQQAVEAGVDGTILVDLPPEEADGVSRVWQKHGLYSIYLCSPTTSAERMNFINQHANGYLYYVSLKGVTGSDALKLPELKAQYLQRKAQSKLPLMVGFGIKTPEMAAQVAEFADGVIVGATLINEIIEAYEAKKDPLQASGALLSSMRQAIDNIGSMV
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: BICL1_DANRE
Sequence: MSASCLDLISAPPQPDSDRMDRALNPGRQNSPDTAGELTLLHTAPGGLGMALEEELAMLTGDREDELQESAPETPVSGQDSDLLSLFRQKEKDLVLAAKLGKALLERNQDLTKQYDKMTKDLNDRLELLEQEKHELRRRLESREGEWEGRVAELETDVQHLQGELERHQLQLRDADREKSRAISELSEQNHRLLEQLSRAAEVEKQLSTQVHSLRDDFKEKSISSNQHMTRLETLQAEIRMLSERKQDLERRVCAVLEENQQLQNTVEELRERTLELEKHCHHKDLQKILPETLLTIIKLKTNYSQKKKKTEHLILHTRRAHTHLCRAPSEVQSCMGSLSCVWCIQRRKDCDLFLLQLRLQLWEAYCQVRSICSQLRGNDITDSALSTDSSMDESSETLSAKDVPTGSLHSSLLELRRLTQNLLDGNESTVALLSVEVSSSREENERLRAMTEVHEPNEQLQSAIRDRDEAIAKKKAVEMELAKCKIDIMSLNSBQLLDAIQQKLNLSQQLEAWQDDMHRVIDQQLMDKHQEEWKDPPFSFSRRGAAASRPTQRLADRDKPLFSFFKKN
What is the function of this protein?
Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin.  Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track).  Predominantly recruits 2 dyneins, which increases both the force and speed of the microtubule motor (By similarity).  Component of secretory vesicle machinery in developing neurons that acts as a regulator of neurite outgrowth (PubMed:20360680).  Regulates the secretory vesicle transport by controlling the accumulation of Rab6-containing secretory vesicles in the pericentrosomal region restricting anterograde secretory transport during the early phase of neuronal differentiation, thereby inhibiting neuritogenesis (By similarity).
What are the official names of this protein?
BICD family-like cargo adapter 1, Bicaudal D-related protein 1, BICD-related protein 1, BICDR-1, Coiled-coil domain-containing protein 64A.
What is the protein family that this protein belongs to?
Belongs to the BICDR family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localizes around the centrosome.
Protein: HMB1_TRIGR
Sequence: NSGVFVNPPFFPTYPHAGEQFYVTPPGSYELSSCAFSSKNPKTSSYSSSSSPPSLTATSKPSCTQQLGAATFYGGGTLSNFSTAGYGDHSTTSAGYGSMSQPISPTSAWDSRMAATYNTTSWGSTAAELGDGSYRGRVNALAAGTGCLVSAAAEPNNNHCSQVMSPCKSTSGYPWMPVAGPNVGLEVGRKRCRQTYTRYQTLELEKEFHFNRYLTRRRRIELSHLLGLTERQIKIWFQNRRMKYKKESKNKEEGVSGEGDGENETESTGTENAQTQNAVHGVTILEKPSSLVLHVDDTIALNTVRHS
What are the official names of this protein?
Homeobox protein HB1, TGHBOX1.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MURQ_ECOK1
Sequence: MQLEKMITEGSNAASAEIDRVSTLEMCRIINDEDKTVPLAVERVLPDIAAAIDVIHTQVSGGGRLIYLGAGTSGRLGILDASECPPTYGVKPGLVVGLIAGGEYAIQHAVEGAEDSREGGVNDLKNINLTAQDVVVGIAASGRTPYVIAGLEYARQLGCRTVGISCNPGSAVSSTAEFAITPVVGAEVVTGSSRMKAGTAQKLVLNMLSTGLMIKSGKVFGNLMVDVVATNEKLHVRQVNIVKNATGCNAEQAEAALIACERNCKTAIVMVLKNLDADEAKKCLDQHGGFIRKALEKE
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.  Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: PUR8_ECOLI
Sequence: MELSSLTAVSPVDGRYGDKVSALRGIFSEYGLLKFRVQVEVRWLQKLAAHAAIKEVPAFAADAIGYLDAIVASFSEEDAARIKTIERTTNHDVKAVEYFLKEKVAEIPELHAVSEFIHFACTSEDINNLSHALMLKTARDEVILPYWRQLIDGIKDLAVQYRDIPLLSRTHGQPATPSTIGKEMANVAYRMERQYRQLNQVEILGKINGAVGNYNAHIAAYPEVDWHQFSEEFVTSLGIQWNPYTTQIEPHDYIAELFDCVARFNTILIDFDRDVWGYIALNHFKQKTIAGEIGSSTMPHKVNPIDFENSEGNLGLSNAVLQHLASKLPVSRWQRDLTDSTVLRNLGVGIGYALIAYQSTLKGVSKLEVNRDHLLDELDHNWEVLAEPIQTVMRRYGIEKPYEKLKELTRGKRVDAEGMKQFIDGLALPEEEKARLKAMTPANYIGRAITMVDELK
What is the function of this protein?
(Microbial infection) Catalyzes the conversion of 2-amino-2'-deoxyadenylo-succinate to dZMP and fumarate, when the bacterium is infected by a phage that produces the substrate of this reaction, a step in the synthesis of dZTP (2-amino-2'-deoxyadenosine 5'-triphosphate), which is a nucleotide then used by the phage as a DNA polymerase substrate.
What are the official names of this protein?
Adenylosuccinate lyase, ASL, Adenylosuccinase, ASase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
Protein: MTA3_BOVIN
Sequence: MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTATGNVEAKVLCFYRRRDISNTLIMLADKHAKEIEEESETTVEADLTDKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNETESVLSYLDKEDTFFYSLVYDPSVKTLLADKGEIRVGPRYQADIPEMLLEGESDEREQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHSMDTLYRHGYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPTYKPNPNQISTSNGKPGAVNGAVGTTFQPQNPLLGRACESCYATQSHQWYSWGPPNMQCRLCATCWLYWKKYGGLKMPTQSEEEKLPPSPATEDPRVRSHMSRQAMQGMPVRNTGSPKSAVNTRQAFFLHTTYFTKFARQVCKNTLRLRQAARRPFVPINYAAIRAEYADRHADLSGSPLKSKSTRKPLACIIGYLEIHPSKKPNVIRSTPSLQTPTTKRMLATPNHTSLSILGKRNYSHHNGLDERLMK
What is the function of this protein?
Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin.  Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels.  Contributes to transcriptional repression by BCL6.
What are the official names of this protein?
Metastasis-associated protein MTA3.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: DAAF6_HUMAN
Sequence: MESENMDSENMKTENMESQNVDFESVSSVTALEALSKLLNPEEEDDSDYGQTNGLSTIGAMGPGNIGPPQIEELKVIPETSEENNEDIWNSEEIPEGAEYDDMWDVREIPEYEIIFRQQVGTEDIFLGLSKKDSSTGCCSELVAKIKLPNTNPSDIQIDIQETILDLRTPQKKLLITLPELVECTSAKAFYIPETETLEITMTMKRELDIANFF
What is the function of this protein?
Plays a role in cytoplasmic pre-assembly of axonemal dynein.
What are the official names of this protein?
Dynein axonemal assembly factor 6, PIH1 domain-containing protein 3, Sarcoma antigen NY-SAR-97.
What is the protein family that this protein belongs to?
Belongs to the PIH1 family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus, trans-Golgi network. Note=Localized to the cytoplasm of spermatogenic cells.
Protein: MT2_COLLI
Sequence: MDPQDCTCAAGDSCSCAGSCKCKNCRCQSCRKSCCSCCPASCSNCAKGCVCKEPSSSKCSCCH
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
What are the official names of this protein?
Metallothionein-2, MT-2, Metallothionein-II, MT-II.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 1 family.
Protein: ASPD_BRADU
Sequence: MDRRWKVMTDQTASSELRVAIAGLGSIGTKIAAALDQGEGLTLSAVAVRDPAKHQAFLNGLRRPPQVLPIDQLGEAADIVVECAPSSQLRAIVEPAVKRGKAAVVVSVGGLLDNFDLVDLARANGGRIIVPTGALIGLDAVNAAVIGTIHSVKMVTRKPIDGLKGAPFIVHNNIDIDTLREPLKLFEGTAREAAKGFPANLNVAVALSLAGVGPDRTSVQIWADPTVTRNVHRIEVEADSARFSMSIENIPSENPKTGLITALSVIALLRKQRATLCVGT
What is the function of this protein?
Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
What are the official names of this protein?
L-aspartate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the L-aspartate dehydrogenase family.
Protein: MURG_ANADE
Sequence: MRMMVAGGGTGGHVFPGIALAEEVVTRHPANDVVFVGTARGLEASVVPAAGFPIELIEVKGLKGKGLVGALLNLLLLPRAFLQSWRILRRWRPDVVVGVGGYASGPVVLTAWAMRIPTAVQEQNAIAGLTNRLLGRVVKAAFTAFPEAARHFAPRKVYQLGNPIRRRLMENYMRPESAHGAPRLLVFGGSQGAHALNMRVIEALPHLADLRERIQITHQTGARDREYVEKGYRACGFTPDVREFIDDMSAAYAGCDLVVCRAGATTLAELTVCKKPSILVPFPAAADNHQVKNARSLVDAGAAVMIEERDLTGEVLAREIRDILDAPERRERMARAAGRLGSPQAAKEIADVCMELVRRRWGSPFGQAREPGQKPARPPDLAS
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NDH_STAAM
Sequence: MAQDRKKVLVLGAGYAGLQTVTKLQKAISTEEAEITLINKNEYHYEATWLHEASAGTLNYEDVLYPVESVLKKDKVNFVQAEVTKIDRDAKKVETNQGIYDFDILVVALGFVSETFGIEGMKDHAFQIENVITARELSRHIEDKFANYAASKEKDDNDLSILVGGAGFTGVEFLGELTDRIPELCSKYGVDQNKVKITCVEAAPKMLPMFSEELVNHAVSYLEDRGVEFKIATPIVACNEKGFVVEVDGEKQQLNAGTSVWAAGVRGSKLMEESFEGVKRGRIVTKQDLTINGYDNIFVIGDCSAFIPAGEERPLPTTAQIAMQQGESVAKNIKRILNGESTEEFEYVDRGTVCSLGSHDGVGMVFGKPIAGKKAAFMKKVIDTRAVFKIGGIGLAFKKGKF
What is the function of this protein?
Alternative, nonproton pumping NADH:quinone oxidoreductase that delivers electrons to the respiratory chain by oxidation of NADH and reduction of quinones, and contributes to the regeneration of NAD(+).
What are the official names of this protein?
Type II NADH:quinone oxidoreductase, NDH-2.
What is the protein family that this protein belongs to?
Belongs to the NADH dehydrogenase family.
What are the subcellular locations of this protein?
Cell membrane.