PharMolix/UniProtQA huggingface dataset:
Protein: RL5_SALRD
Sequence: MADVPRLQKQYQDEVRPSLTDQFGYENPMEVPRLEKICVNRGVGEVSENQKALDQAVEEMRKITGQHPTIRRAKRSIASFDVREGMPVGVKVTLREARMYEFFDRLVTLALPNIRDFRGVPDRSFDGRGNYTLGIDEQIIFPEIDVDNVDRIDGMDITFVTDAETDEESYALLKGLGMPFVRRGDEEPAEA
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: ANMK_SALDC
Sequence: MKSGRFIGVMSGTSLDGVDVVLAAIDETMVAQQASLTWPIPVHLKKGILDICQGQPLTLSQLGQLDTQLGRLFAQAVNALLAQQRLQPRDIVAIGCHGQTVWHEPTGEAPHTLQIGDNNHIVAHTGITVVGDFRRRDIALGGQGAPLVPAFHHALLGHPTEKRMVLNIGGIANLSLLFPGQAVRGYDTGPGNMLMDAWIWRQCAQPYDKDAAWAKEGQVILPLLQKMLRDPYFAASAPKSTGREYFNYGWLERHLAAFPGADARDVQATLAELTAVSIAQQVLLNGGCERLMVCGGGGRNPLVMARLAALLPGIEVSTTDKAGISGDDMEALAFAWLAWRTLAGLPGNLPSVTGATEASVLGAIYPANPITQS
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: LPXA_VIBVU
Sequence: MIDATAQIHPTAVVEEGAVIGANVKIGPFCYVDSKVEIGEGTELLSHVVVKGPTKIGKENRIFQFASIGEQCQDLKYAGEDTQLVIGDRNTIRESVTMHRGTVQDKGITIVGSDNLFMINAHVAHDCVIGDRCIFANNATLAGHVKVGNQAIVGGMSAIHQFCHIGDHCMLGGGSIVVQDVPPYVMAQGNHCAPFGINVEGLKRRGFEKKEILAIRRAYKTLYRSGLTLEAAKEEIAKETEAFPAVKLFLEFLEKSQRGIIR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_GLUDA
Sequence: MRQMIVGNWKMNGLGAPSRDLVGEIAEGLATIPSPPQVVVCPPFTQLAGIGPLLKGSGIALGAQDCHQAASGAHTGDISAAMLADLGVEYVVLGHSERRRDHGELDETVREKTQTALAAGLTPIVCIGETGDQKASGESRDAIGWQIQGSLPDGFSGVVAYEPVWAIGSGNPAASQDIADMMGFIRAELVRQFGAAGKTIRILYGGSVNGRDAASILPIAEVGGALVGSASLQADTFLPIVRAAVDL
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DBP5_CRYNB
Sequence: MSDAQAPPASTSWADMVDEDEKQKQEQNMSNQNDGWGETATETSAPAPPPASAPVSSSNNDGWGEPAPSAPADNGWADAGASNGGSGANNNDGWFDAPVPPSSQPPKKEASDIQLQDDTEGLITNTFQVEVKLADLQGDPNSPLYSVQSFKELNLHEDLMKGIIAAGFQKPSKIQEKALPLLLSNPPRNLIGQSQSGTGKTAAFTLNMLSRVDPTIPTPQAICIAPSRELARQIQEVVDQIGQFTQVGTFLAIPGSWSRNSRIDKQILIGTPGTLVDMLMRGSRILDPRMIRVLVLDEADELIAQQGLGEQTFRIKQLLPPNVQNVLFSATFNDDVQEFADRFAPEANKIFLRKEDITVDAIRQLYLECDSEDQKYEALSALYDCLVIGQSIVFCKRKVTADHIAERLISEGHAVASLHGDKLSQERDAILDGFRNGETKVLITTNVIARGIDIPAVNMVVNYDVPDLGPGGNGPDIETYIHRIGRTGRFGRKGCSVIFTHDYRSKSDVERIMNTLGKPMKKIDARSTTDIEQLEKALKLAMKGPA
What is the function of this protein?
ATP-dependent RNA helicase associated with the nuclear pore complex and essential for mRNA export from the nucleus.  May participate in a terminal step of mRNA export through the removal of proteins that accompany mRNA through the nucleopore complex.  May also be involved in early transcription (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase DBP5.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX19/DBP5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Nuclear pore complex cytoplasmic fibrils.
Protein: NADA_PSEAE
Sequence: MTHISERLLVQAHLAAKQPRVLSEQESAEHRAAIAAELKAQNAVLVAHYYCDPVIQALAEETGGCVSDSLEMARFGNQHPAQTVVVAGVRFMGETAKILNPEKRVLMPTLEATCSLDLGCPVDEFSAFCDQHPERTVVVYANTSAAVKARADWVVTSSCAVEIVEHLMDNGEPILWAPDQHLGRYIQRETGADMLLWDGACIVHEEFKAKQLEDMKALYPDAAILVHPESPESVVALADAVGSTSQLIKAAQTLPNKTFIVATDRGIFYKMQQLCPDKDFIEAPTAGNGAACRSCAHCPWMAMNTLERTLACLREGSGEIFVDPALIPRAVRPLKRMLDFTQAARLRQAGNA
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TUSD_YERE8
Sequence: MSGLKYGLMVTGPAYGTQQASSAYQFAQALINSGHHLVSVFFYREGVLNANQLTTPANDEFDLVRAWQQLANEHAVILNVCVAAALRRGITDQHEAEQLNLAAANLQPGFTLSGLGALAEAALTCDRMVQF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.  Accepts sulfur from TusA and transfers it in turn to TusE.
What are the official names of this protein?
Sulfurtransferase TusD, tRNA 2-thiouridine synthesizing protein D.
What is the protein family that this protein belongs to?
Belongs to the DsrE/TusD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUX1B_NEUCR
Sequence: MRASLLAFSLAAAVAGGQQAGTLTAKRHPSLTWQKCTRGGCPTLNTTMVLDANWRWTHATSGSTKCYTGNKWQATLCPDGKSCAANCALDGADYTGTYGITGSGWSLTLQFVTDNVGARAYLMADDTQYQMLELLNQELWFDVDMSNIPCGLNGALYLSAMDADGGMRKYPTNKAGAKYATGYCDAQCPRDLKYINGIANVEGWTPSTNDANGIGDHGSCCSEMDIWEANKVSTAFTPHPCTTIEQHMCEGDSCGGTYSDDRYGVLCDADGCDFNSYRMGNTTFYGEGKTVDTSSKFTVVTQFIKDSAGDLAEIKAFYVQNGKVIENSQSNVDGVSGNSITQSFCKSQKTAFGDIDDFNKKGGLKQMGKALAQAMVLVMSIWDDHAANMLWLDSTYPVPKVPGAYRGSGPTTSGVPAEVDANAPNSKVAFSNIKFGHLGISPFSGGSSGTPPSNPSSSASPTSSTAKPSSTSTASNPSGTGAAHWAQCGGIGFSGPTTCPEPYTCAKDHDIYSQCV
What are the official names of this protein?
Exoglucanase 1, 1,4-beta-cellobiohydrolase 1, Exocellobiohydrolase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 7 (cellulase C) family.
What are the subcellular locations of this protein?
Secreted.
Protein: ULK1_HUMAN
Sequence: MEPGRGGTETVGKFEFSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLLGKEIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHAMRTLSEDTIRLFLQQIAGAMRLLHSKGIIHRDLKPQNILLSNPAGRRANPNSIRVKIADFGFARYLQSNMMAATLCGSPMYMAPEVIMSQHYDGKADLWSIGTIVYQCLTGKAPFQASSPQDLRLFYEKNKTLVPTIPRETSAPLRQLLLALLQRNHKDRMDFDEFFHHPFLDASPSVRKSPPVPVPSYPSSGSGSSSSSSSTSHLASPPSLGEMQQLQKTLASPADTAGFLHSSRDSGGSKDSSCDTDDFVMVPAQFPGDLVAEAPSAKPPPDSLMCSGSSLVASAGLESHGRTPSPSPPCSSSPSPSGRAGPFSSSRCGASVPIPVPTQVQNYQRIERNLQSPTQFQTPRSSAIRRSGSTSPLGFARASPSPPAHAEHGGVLARKMSLGGGRPYTPSPQVGTIPERPGWSGTPSPQGAEMRGGRSPRPGSSAPEHSPRTSGLGCRLHSAPNLSDLHVVRPKLPKPPTDPLGAVFSPPQASPPQPSHGLQSCRNLRGSPKLPDFLQRNPLPPILGSPTKAVPSFDFPKTPSSQNLLALLARQGVVMTPPRNRTLPDLSEVGPFHGQPLGPGLRPGEDPKGPFGRSFSTSRLTDLLLKAAFGTQAPDPGSTESLQEKPMEIAPSAGFGGSLHPGARAGGTSSPSPVVFTVGSPPSGSTPPQGPRTRMFSAGPTGSASSSARHLVPGPCSEAPAPELPAPGHGCSFADPITANLEGAVTFEAPDLPEETLMEQEHTEILRGLRFTLLFVQHVLEIAALKGSASEAAGGPEYQLQESVVADQISLLSREWGFAEQLVLYLKVAELLSSGLQSAIDQIRAGKLCLSSTVKQVVRRLNELYKASVVSCQGLSLRLQRFFLDKQRLLDRIHSITAERLIFSHAVQMVQSAALDEMFQHREGCVPRYHKALLLLEGLQHMLSDQADIENVTKCKLCIERRLSALLTGICA
What is the function of this protein?
Serine/threonine-protein kinase involved in autophagy in response to starvation (PubMed:18936157, PubMed:21460634, PubMed:21795849, PubMed:23524951, PubMed:25040165, PubMed:31123703, PubMed:29487085).  Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes (PubMed:18936157, PubMed:21460634, PubMed:21795849, PubMed:25040165).  Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR (PubMed:21795849).  Activated via phosphorylation by AMPK and also acts as a regulator of AMPK by mediating phosphorylation of AMPK subunits PRKAA1, PRKAB2 and PRKAG1, leading to negatively regulate AMPK activity (PubMed:21460634).  May phosphorylate ATG13/KIAA0652 and RPTOR; however such data need additional evidences (PubMed:18936157).  Plays a role early in neuronal differentiation and is required for granule cell axon formation (PubMed:11146101).  May also phosphorylate SESN2 and SQSTM1 to regulate autophagy (PubMed:25040165).  Phosphorylates FLCN, promoting autophagy (PubMed:25126726).  Phosphorylates AMBRA1 in response to autophagy induction, releasing AMBRA1 from the cytoskeletal docking site to induce autophagosome nucleation (PubMed:20921139).  Phosphorylates ATG4B, leading to inhibit autophagy by decreasing both proteolytic activation and delipidation activities of ATG4B (PubMed:28821708).
What are the official names of this protein?
Serine/threonine-protein kinase ULK1, Autophagy-related protein 1 homolog, ATG1, hATG1, Unc-51-like kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.
Protein: CYCA_PETHY
Sequence: MVGVNSLRSALYLIVLILFVQLTYFSDARVMDVDLSRAFLPLTGIGCGESCVWIPCVSAAIGCSCSNKICYRNGIIPKK
What is the function of this protein?
Probably participates in a plant defense mechanism.
What are the official names of this protein?
Cyclotide phyb-A.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Bracelet subfamily.
Protein: NDMB_PSEPU
Sequence: MKEQLKPLLEDKTYLRHFWHPVCTLNEFERANASGHGPMGVTLLGEKLVLARLNSKIIAAADRCAHRSAQLSIGRVCSNAGKDYLECPYHGWRYDEAGACQLIPACPDKSISPRAKISSFDCEVKYDIVWVRLDNSFDCTQIPYLSDFDNPDMQVIVADSYIWETVAERRWENFTDFSHFAFVHPGTLYDPFFASHPTVYVNRVDGELQFKLAPPREMKGIPPEAPMGDFTYRCTMPYSVNLEIKLWKDDSRFVLWTTASPVDNKSCRNFMIIVREKDNQPDHMHLAFQKRVLDEDQPVIESQWPLEIQTSEVSVATDKISVQFRKWHKELSLSAVEGREAFRDSVLTNVIEEEQ
What is the function of this protein?
Involved in the caffeine degradation, which is the essential first step for assimilating the carbon and nitrogen in caffeine.  Catalyzes the N3-demethylation of theobromine to produce 7-methylxanthine and formaldehyde.  Also catalyzes the N3-demethylation of 3-methylxanthine, caffeine, and theophylline to xanthine, paraxanthine, and 1-methylxanthine, respectively.  NADH is the preferred substrate.
What are the official names of this protein?
Methylxanthine N3-demethylase NdmB, 3-methylxanthine demethylase.
Protein: TMTC1_HUMAN
Sequence: MVVTTSARGGGGDRTPSRRRGCGLAPAGAAALLAGASCLCYGRSLQGEFVHDDVWAIVNNPDVRPGAPLRWGIFTNDFWGKGMAENTSHKSYRPLCVLTFKLNIFLTGMNPFYFHAVNIILHCLVTLVLMYTCDKTVFKNRGLAFVTALLFAVHPIHTEAVAGIVGRADVLACLLFLLAFLSYNRSLDQGCVGGSFPSTVSPFFLLLSLFLGTCAMLVKETGITVFGVCLVYDLFSLSNKQDKSSNGALCPRSPQQPGSPQPSSLPGHPHRENGKQQRFPHKGAWGGCHSPLPPEPKSSGFPVSPRAVWSMMRFLTYSYLLAFNVWLLLAPVTLCYDWQVGSIPLVETIWDMRNLATIFLAVVMALLSLHCLAAFKRLEHKEVLVGLLFLVFPFIPASNLFFRVGFVVAERVLYMPSMGYCILFVHGLSKLCTWLNRCGATTLIVSTVLLLLLFSWKTVKQNEIWLSRESLFRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTLTRDTAEAKMYYQRALQLHPQHNRALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVAHKAEILSPLGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCLECYRLLSAIYSKQENHDKALDAIDKALQLKPKDPKVISELFFTKGNQLREQNLLDKAFESYRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAYYERALQLVPDSKLLKENLAKLDRLEKRLQEVREKDQT
What is the function of this protein?
Transfers mannosyl residues to the hydroxyl group of serine or threonine residues.  The 4 members of the TMTC family are O-mannosyl-transferases dedicated primarily to the cadherin superfamily, each member seems to have a distinct role in decorating the cadherin domains with O-linked mannose glycans at specific regions.  Also acts as O-mannosyl-transferase on other proteins such as PDIA3.
What are the official names of this protein?
Protein O-mannosyl-transferase TMTC1, Transmembrane and TPR repeat-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the TMTC family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Endoplasmic reticulum.
Protein: INSIG_MYCVP
Sequence: MRLRISEAVVLFLLGAVAALIGDHSHVVTGTTVYHTDAVPFVWSSPFWFPILVGAATASLAELRLHLPAPRDGVTARQALGGVAAVVGTYVTTALVHAFPVVPVTALVCAAAAITWCVLGDGPGAACGVVIAVIGPAVEIALVQLGVFAYHPDSDGLFGVAPFLAPLYFAFGVVAALLGELAVARRPQLGPPVCDTVSRGPGAG
What is the function of this protein?
Diacylglycerol-binding protein.
What are the official names of this protein?
INSIG protein homolog, MvINS.
What is the protein family that this protein belongs to?
Belongs to the INSIG family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: DBP2_SCLS1
Sequence: MSYGGGYGGGRGGGNGYGNGDSSYGRGNSYSNGYSNGGSNGYSGGGGGGYGGGRGGSGGGNVNGYSGGGGGYGGGGGYGGGGGAGGDRMNNLGANLQKQNWDLNTLPKFEKSFYKEDPVVAARSEEDVAKFRAQHNIAVQGPNIPKPVETFDEAGFPAYVMTEVKAQGFPAPTPIQSQGWPMALSGRDVVGIAETGSGKTLTYCLPAIVHINAQPLLAPGDGPIVLVLAPTRELAVQIQQEITKFGKSSRIRNTCVYGGVPKGGQIRDLAKGVEVCIATPGRLIDMIESGKTNLRRVTYLVLDEADRMLDMGFEPQIRKILGQIRPDRQTCMWSATWPKEVRALASDYLNDFIQVNIGSLELSANHRITQIVEVVSEFEKRDKMTKHLEKIMEDKDNKILIFTGTKRVADDITRFLRQDGWPALSIHGDKQQNERDWVLNEFKTGKSPIMVATDVASRGIDVRNITHVFNYDYPNNSEDYIHRIGRTGRAGQKGTAITLFTTDNQKQARDLVNVLTEAKQVIDPRLAEMTRFGGGGGGRGYGGRGYGGGRGRGGGGNFSSSNAAPLGGGRRW
What is the function of this protein?
ATP-dependent RNA helicase involved nonsense-mediated mRNA decay and ribosome biogenesis through rRNA processing.
What are the official names of this protein?
ATP-dependent RNA helicase dbp2.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: JMJ19_ARATH
Sequence: MGIEGVSTYLKSGNMDTISAPPGFVSQTSFVLRNVPRDKESPRSVSRQEQTTGFGTDDKDSCNMFLKSRPWIVHGHTIPSSEALRPKKTEVRRRRPLKVSETKVLEEAPVFNPTEEEFRDTLSYISSLRDRAEPYGICCVVPPPSWKPPCLLKEKQIWEASTFFPQVQLFGIQTENRKIKKEVDADSNDAASEGVQLCRVERGPGYTLKSFKNFADTYKKSHFGMKDEVLGSENSSPSLKPNELIVADIEKEYRQIVESPLIEIGVLYGNDLDTATFGSGFPLSAPSESSKYSSGWNLNSTAKLPGSLLSLEDCESVCVPRLSVGMCLSSQFWKSEKERLYSLCYLHVGAPRVWYSVAGCHRSKFKAAMKSFILEMSGEQPKKSHNPVMMMSPYQLSVEGIPVTRCVQHPGQYVIIFPGSYYSAFDCGFNCLEKANFAPLDWLPHGDIAVQVNQEMSKTSLISYDKLLFSAAREAVKCLKEYGLSKKNTACYTRWNDSCGTDGLFSNIIKSRIKLEKNRREFLISSLESQRMDKSYDAVNKRECCVCLGDLYLSAVNCSCSANRYSCLNHMRKLCACPCDRKSFLYRYTMDELNLLVEALEGKKLSSMFRWAGIDQKFCASPATTSSKPEEDKGKETDEVTPCNITRKDVAAGTKDQTRVKARSLADILNVKDGNNDAKETLESCSKKSNRPCDNDSSEANAPKKQKQ
What are the official names of this protein?
Probable inactive lysine-specific demethylase JMJ19, Jumonji domain-containing protein 19, AtJMJ19, Protein JUMONJI 19.
What is the protein family that this protein belongs to?
Belongs to the JARID1 histone demethylase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MUTL_STAA8
Sequence: MGKIKELQTSLANKIAAGEVVERPSSVVKELLENAIDAGATEISIEVEESGVQSIRVVDNGSGIEAEDLGLVFHRHATSKLDQDEDLFHIRTLGFRGEALASISSVAKVTLKTCTDNANGNEIYVENGEILNHKPAKAKKGTDILVESLFYNTPARLKYIKSLYTELGKITDIVNRMAMSHPDIRIALISDGKTMLSTNGSGRTNEVMAEIYGMKVARDLVHISGDTSDYHIEGFVAKPEHSRSNKHYISIFINGRYIKNFMLNKAILEGYHTLLTIGRFPICYINIEMDPILVDVNVHPTKLEVRLSKEEQLYQLIVSKIQEAFKDRILIPKNNLDYVPKKNKVLHSFEQQKIEFEQRQNTENNQEKTFSSEESNSKPFMEENQNDEIVIKEDSYNPFVTKTSESLIADDESSGYNNTREKDEDYFKKQQEILQEMDQTFDSNDGTTVQNYENKASDDYYDVNDIKGTKSKDPKRRIPYMEIVGQVHGTYIIAQNEFGMYMIDQHAAQERIKYEYFRDKIGEVTNEVQDLLIPLTFHFSKDEQLVIDQYKNELQQVGIMLEHFGGHDYIVSSYPVWFPKDEVEEIIKDMIELILEEKKVDIKKLREDVAIMMSCKKSIKANHYLQKHEMSDLIDQLREAEDPFTCPHGRPIIINFSKYELEKLFKRVM
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: SYM_CORJK
Sequence: MSKRVLTSVAWPYANGPRHIGHVAGFGVPSDVFARYQRMAGNEVLMVSGTDEHGTPLLVQAEKEGTTVQELADRYNRIIVEDLAGLGLSYDLFTRTTTRNHYAVVQELFTGLYNNGYMVTQTTRGAISPSTGRTLPDRYIEGTCPICGAKDARGDQCDNCGNQLDPEDLIDPRSKINGETPEFIDTEHFMLDLPALAEALTTWLKGRTDWRPNVLKFSLNLLEDIRPRAMSRDIDWGVPIPVEGWQDNNAKKLYVWFDAVVGYLSASIEWAWRIGDPDAWRKWWNDPEALSYYFMGKDNITFHSQIWPAELLGYGGQGSKGGEAGDLADPALNLPTEVVSSEFLTMSGSKFSSSKGVVIYVRDFLKEFGPDALRYFIATAGPETTDTDFTWDEFVRRINSELANEWGNLVNRTVSMAYKNFGEVPTPGPLTAEDEALLAESAKAFDVVGDNINLSRFKAGITEAMRIAGRANQYIAAMEPWKLAKDENQRERLATVLYTALQVVSDVNTLLTPYLPFSAQKIFETLGGEGIWAAQPEVVEVTDESPREPVGVGLPEEGRTYPVIMGDYTKQKVTWARQEIQPGTQLSKPKPLFPKLDPELAETGPEWAPVQK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_WIGBR
Sequence: MKLKPLILSNWKLNGNCLLVKKILLKLNEKLKNKNNLKVVIAPPVIYLSEFKKYVLKKNIFLAAQNVDVNLTGSFTGEISPIMLYEFGVKYVIIGHSERRLYHNESIEDVTKKFLILKKFNLIPVLCIGETKKNKDDKCIENEIVKQIDFILKKIGIEGFINTVIAYEPTWAIGKKDSASPKYIQKIHKFIRNYLSKYDNDISKKIILQYGGSVNSKNVKKIISQKDVNGVLLGRSSTNIEEFLYILDIIEKTKKS
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SC24B_ARATH
Sequence: MAAPVPPGAYRPNNNQQNSGGPPNFVPGSQGNPNSLAANMQNLNINRPPPPMPGSGPRPSPPFGQSPQSFPQQQQQQPRPSPMARPGPPPPAAMARPGGPPQVSQPGGFPPVGRPVAPPSNQPPFGGRPSTGPLVGGGSSFPQPGGFPASGPPGGVPSGPPSGARPIGFGSPPPMGPGMSMPPPSGMPGGPLSNGPPPSGMHGGHLSNGPPPSGMPGGPLSNGPPPPMMGPGAFPRGSQFTSGPMMAPPPPYGQPPNAGPFTGNSPLSSPPAHSIPPPTNFPGVPYGRPPMPGGFPYGAPPQQLPSAPGTPGSIYGMGPMQNQSMTSVSSPSKIDLNQIPRPGSSSSPIVYETRVENKANPPPPTTVDYITRDTGNSSPRYMRCTINQIPCTVDLLSTSGMQLALIVQPMALSHPSEEPIQVVDFGESGPVRCSRCKGYVNPFMKFIDQGRKFICNLCGYTDETPRDYQCNLGPDGRRRDADERPELCRGTVDFVATKEYMVRDPMPAVYFFLIDVSMNAIQTGATAAACSAIQQVLSDLPEGPRTFVGIATFDSTIHFYNLKRALQQPLMLIVPDVQDVYTPLETDVIVQLSECRQHLEILLESIPTMFQESKSPESAFGAAVKAAFLAMKSTGGKLMVFQSVLPSVGIGALSSREADGRANASAGEKEAHKLLQPADKTLRTMAIEFAEYQVCVDLFITTQAYVDMASISEIPRTTGGQVYCYYPFSALSDPPKLYNDLRWNITRPQGFEAVMRVRCSQGIQVQEYSGNFCKRIPTDIDLPAIDCDKAIMVTLKHDDKLQDGAECGFQCALLYTTISGERRIRVLNLSIPCTNMLSNLFRSADLDSQFACMLKQAANEIPSKALPLVKEQATNDCITILHSYRKFCATVTSTGQLILPEALKLLPLYTLALTKGVGLRMDGRIDDRSFWINHVSSLSTPLAIPLVYPRMIAVHDLDANDNEENVVPCPIPLQSEHLSDEGVYFLENGEDGLIYIGESVNSDILQKLFNVRSAAELPSQYVLQKYDNQLSKKFNDVVNEIRRQRSSYLRIKLCKKGDPAGNMLFQSYMVEDRGSGGASYVDFLVSVHRQIQHKLN
What is the function of this protein?
Component of the coat protein complex II (COPII), that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus.  COPII is composed of at least five proteins: the SEC23/24 complex, the SEC13/31 complex, and the protein SAR1.  Acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex.
What are the official names of this protein?
Protein transport protein SEC24 B, Lst1-homolog protein A, AtLst1A, Protein of the clone eighty-four.
What is the protein family that this protein belongs to?
Belongs to the SEC23/SEC24 family. SEC24 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein.
Protein: UVRAG_HUMAN
Sequence: MSASASVGGPVPQPPPGPAAALPPGSAARALHVELPSQQRRLRHLRNIAARNIVNRNGHQLLDTYFTLHLCSTEKIYKEFYRSEVIKNSLNPTWRSLDFGIMPDRLDTSVSCFVVKIWGGKENIYQLLIEWKVCLDGLKYLGQQIHARNQNEIIFGLNDGYYGAPFEHKGYSNAQKTILLQVDQNCVRNSYDVFSLLRLHRAQCAIKQTQVTVQKIGKEIEEKLRLTSTSNELKKKSECLQLKILVLQNELERQKKALGREVALLHKQQIALQDKGSAFSAEHLKLQLQKESLNELRKECTAKRELFLKTNAQLTIRCRQLLSELSYIYPIDLNEHKDYFVCGVKLPNSEDFQAKDDGSIAVALGYTAHLVSMISFFLQVPLRYPIIHKGSRSTIKDNINDKLTEKEREFPLYPKGGEKLQFDYGVYLLNKNIAQLRYQHGLGTPDLRQTLPNLKNFMEHGLMVRCDRHHTSSAIPVPKRQSSIFGGADVGFSGGIPSPDKGHRKRASSENERLQYKTPPPSYNSALAQPVTTVPSMGETERKITSLSSSLDTSLDFSKENKKKGEDLVGSLNGGHANVHPSQEQGEALSGHRATVNGTLLPSEQAGSASVQLPGEFHPVSEAELCCTVEQAEEIIGLEATGFASGDQLEAFNCIPVDSAVAVECDEQVLGEFEEFSRRIYALNENVSSFRRPRRSSDK
What is the function of this protein?
Involved in maintaining chromosomal stability.  Promotes DNA double-strand break (DSB) repair by association with DNA-dependent protein kinase complex DNA-PK and activating it in non-homologous end joining (NHEJ) (PubMed:22542840).  Required for centrosome stability and proper chromosome segregation (PubMed:22542840).
What are the official names of this protein?
UV radiation resistance-associated gene protein, p63.
What are the subcellular locations of this protein?
Late endosome. Lysosome. Cytoplasmic vesicle, autophagosome. Early endosome. Endoplasmic reticulum. Midbody. Chromosome, centromere. Note=Colocalizes with RAB9-positive compartments involved in retrograde transport from late endosomes to trans-Golgi network. Colocalization with early endosomes is only partial (PubMed:24056303). Recruited to autophagosome following interaction with RUBCNL/PACER (PubMed:28306502).
Protein: PA50C_BISBO
Sequence: SQISLRGSNLTI
What are the official names of this protein?
Pregnancy-associated glycoprotein 50C, EbPAG-C 50 kDa.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: RL6_BARQU
Sequence: MSRIGKKPISVPSGVTATVEGQLVKAKGPKGELSYIVNDEVLVKFEGNVISVSPRDQSKDARSKWGMSRSMIENIFCGVKNGFEKKLEINGVGYRAALQGKDVQLSLGFSHDVIYKVPPGITVTVPKPTEIVISGIDKQQVGQVAAEIREYRRPEPYKGKGVKHADECIFRKEGKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: PSBF_HELAN
Sequence: MTIDRTYPIFTVRWLAVHGLAVPTVSFLGSISAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.