PharMolix/UniProtQA huggingface dataset:
Protein: IGLR2_CAEEL
Sequence: MRKFVFFVVAILIQIHTTTSQRNRSSSPSGFLDLQLEKCPQVLGCRCVRDSTRNIQCFSIDESKLLEIQKIYGSNIQRLELHNWQHDQLNFDIFAPFPQLEHIILRDGDLESLNGTVIHPTLKVLSIENSELTSSSEVCRLLSIFPKIQSLSLSKNYFEKFECDTSNTKLKILDLSQNRISHLEVPNTLRVLNVSRNRLTSFENISTKLTDLDISFNKLSLWPSFDDWKFPNLRSLSAIKLDLQTGFQLDAPLLNSLNIDGASLRYLNFHQILTPKLKKFSARYLTELRNIAGRLPSTVTDVAFTDTMLRTLPADFIPMSSTNHMQKVSFDFSTNQLLCDKCLLQWSLPVYAQTSIRKDCNLTREEIESASCKIGVVANDTGIQYGKYEKPTAISCFSYGVPSPKISWWRFRPAEKLGSYDPITDEISYTNVSETMKESYEIQSGGSLLIRSPNRSHVERYVCVVENEYGKDYGIYHFRLDYLDWYSYDVFNSVFWGGLATSLIVCLISFLLNITWILTRKSALWWIQRAERLSRVRKMVEAMEKYRVRQMESLHEKYTKRVQIVRDNYHQQVEALRVSYASQQEKFQNYKAAQVDAVHSHLDAMRDGYNNQLGRVREYGSKRAEQLWESYERQVNRMRTFSLQHRLKMMRQYKVKQRYVNKLLESLQATSPEVQLENEEKVRAALEIPDDLATIDGSMDTPSRLSRSSSFHSLPEYVIDEQGNVRPGIIPTNAPSIRFTTKPTTSSISNEASTSSPSSSGAHRSPDSPPEKR
What are the official names of this protein?
Immunoglobulin domain and leucine-rich repeat-containing protein 2.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: LPL_SHIFL
Sequence: MTHIVRFIGLLLLNASSLRGRRVSGIQH
What is the function of this protein?
Involved in control of the biosynthesis of leucine.
What are the official names of this protein?
leu operon leader peptide, leu operon attenuator peptide.
Protein: EFG1P_COPC7
Sequence: MAPIRTKDKHKNAEASSSKSNKSHKKKPNHQPKASALPGKQKIKSSLRQVRRLLAKENLAADKRVEAERRLKALEAELQQVEQAHKERALAIRYHKVKFFERQKVTRKLNQVKRRLDSADGSEKEQLEAQLLEERVNLNYILHYPKTKKYISLFPPEVRKGEVTEASKTDAEKTNREREEIRQWIRDSMEKKELPSEPETQLGSGPGRPQASTQFPSKKSSNPVTKSGVQSSKPGDDIEDDEFFGNDSEDDGNEVEDEEDEDEED
What is the function of this protein?
Involved in rRNA processing.
What are the official names of this protein?
rRNA-processing protein EFG1.
What is the protein family that this protein belongs to?
Belongs to the EFG1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: DER_STRR6
Sequence: MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYATGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEYVARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIVENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFTDTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDKRIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQRLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKPPTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: RSSA_PLACH
Sequence: MSNKKVQSPKEESIAKMLICKVHIGTKNLENKMKRYVYTRAKDGVHIINLAKTYEKLQLAARVIVAVSNPADVVVVSARPFGSRAVLKFAQYTGAQAIAGRWTPGMLTNQIIQKFIEPRLLIVTDPRTDAQSVKESAYANIPVIALCDSDSPLEHVDIAIPCNNKGKESIALMYWLLAQEVLYLKGSIPRSQAWDVMVDMFLWRDPEQFELKNLANEEATPTAPHLADNQYATDAPYDDWNKKDDWNDNANEEWKNPIAVDEW
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein SA.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_SHIDS
Sequence: MKRTFQPSVLKRNRSHGFRARMATKNGRQVLARRRAKGRARLTVSK
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: TPIC_SPIOL
Sequence: MAVVSTSLASQITNPNSAVSTQFSGLRRSFLKLENSVSTQSSFFQNVDSHLRLSSSSRRCPRGVVAMAGSGKFFVGGNWKCNGTKESITKLVSDLNSATLEADVDVVVAPPFVYIDQVKSSLTGRVEISAQNCWIGKGGAFTGEISVEQLKDLGCQWVILGHSERRHVIGEQNEFIGKKAAYALNQGVGVIACIGELLEEREAGKTFDVCYQQLKAFADALPSWDNVVVAYEPVWAIGTGKVASPDQAQEVHVAVRDWLKKNVSEEVASKTRIIYGGSVNGGNCAELAKQEDIDGFLVGGASLKGPEFATIVNSVTAKKVAA
What are the official names of this protein?
Triosephosphate isomerase, chloroplastic, TIM, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: KCY_RHOP5
Sequence: MIIAIDGPAASGKGTLAKRLAAHYGLRHLDTGVIYRAVGMGMLALGAELTDEARAAAVAAALDPKTFDDPALKSQAVGEAASVVSALPKVRAALVDFQRRFADTPPGAVLDGRDIGTVICPQAEVKIFVVADPVVRARRRTLEAQSRGEPADEAVILADILKRDERDRSRAAAPLKQADDAHLLDNSHLDVESGLRAAIDIVEAVRAGRLR
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CADH7_MOUSE
Sequence: MKLGKVELCHFLQLIALFLCFSGMSQAELPRSRSKPYFQSGRSRTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGASSIFIIDENTGDIHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYTAGVPEMSPVGTSVVQVTATDADDPTYGNSARVVYSILQGQPYFSVEPKTGVIKTALPNMDREAKDQYLLVIQAKDMVGQNGGLSGTTSVTVTLTDVNDNPPRFPRRSYQYNVPESLPVASVVARIKAADADIGVNAEMEYKIVDGDGLGIFKISADKDTQEGIITIQKELDFEAKTSYTLRIEAANRDADPRFLSLGPFSDTTTVKIIVEDVDEPPVFSSPLYPMEVSEATQVGHIIGTVAAHDPDSSNSPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRETNAVHNITVLAMESQNPSQVGRGYVAITILDINDNAPEFAMDYETTVCENAQPGQVIQKISAVDKDEPSNGHQFYFSLTTDMTNNHNFSLKDNKDNTASILTRRNGFRRQEQSVYYLPIFIVDSGSPSLSSTNTLTIRVCDCDADGIAQTCNAEAYVLPAGLSTGALIAILACVLTLLVLILLIVTMRRRKKEPLIFDEERDIRENIVRYDDEGGGEEDTEAFDMAALRNLNAIRDSKTRRDVTPEIQFLSRPTFKNIPDNVIFREFIWERLKEADVDPGAPPYDSLQTYAFEGNGSVAESLSSLDSISSNSDQNYDYLSDWGPRFKRLAEMYGNGQESLYS
What is the function of this protein?
Cadherins are calcium-dependent cell adhesion proteins.  They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (By similarity).
What are the official names of this protein?
Cadherin-7.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: LTPG8_ARATH
Sequence: MNITRILGVVTTVVILYSVQVTAQFFGDVQQAMRCVAKLMPCQPYIHLSIPPPPLCCNPMKQIAEKDVSCLCTAFKHPDLLRFLALTKENAIKILDSCGINHDPSVCNKTNPSSPAALPEAATSGNSFSTKKNTALAITFFGFSFVFLGMII
What is the function of this protein?
Probable lipid transfer protein.
What are the official names of this protein?
Non-specific lipid transfer protein GPI-anchored 8, AtLTPG-8, Protein LTP-GPI-ANCHORED 8.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: LPXB_XANOR
Sequence: MTGIGNQTSGIETGVHDRAPADGEPTALPISHSPLPIPGAHARPPRFALIAGEASGDILGAGLIAQLRLRYPNAEFVGIGGDAMRGAGCQTWFDASELAVMGLTEVLRHLPRLLKLRSAFRERVLAWKPDVFIGIDAPDFNLPVERWLKQRGIKTVHYVSPSVWAWREKRAEKIAVSADLVLCLFPMEPPIYAKHGVDARFVGHPMADDIAYQADRDAARATLGLSASSTVLAVLPGSRHGEISRLGDTFLQAAWLVCEHIPNLHVLVPAANAGCKQLLAEQLSRSSLPVMRSHLINGQARTAMLAADVVLLASGTATLEAMLVKRPMVVGYKVAPLTYRIVKLLGLIKVNRYALPNILANDDLAPELMQDDCMPERLCVALLDWLKHPAKVAALQPRYLALHAALRRDASARAAEAVAGLLQGRDWSGANI
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: MTNA_DESAL
Sequence: MNVNGKWYRAIWPNEHDPETVEIIDQRKLPHRFEIVGLTTVKKTIQAIRDMYVRGAPLIGATGAWGVYLAVVNMKDAENPLQYLKEECFKISNARPTAVNLEWAVKAMEAAILEKSNVEDWIKAAWSKAIEITEAEVKNCRQIGVHGSPLIEEISKNKNGKTVNILTHCNAGWLACVDHGTATAPIYAAFDKGIDVHVWVDETRPLNQGSRLTAWELGQHGVPHTIITDNAGGHLMQHGKVDMVIVGTDRTTHTGDVANKVGTYLKALAAKDNNVPFYVALPSSTIDWEMKNGVKDIPIENRDPDEVRKVWGLHDGHLVDVLVPPEESPALNVAFDVTPARLVTGLITERGLCKASEEGVRSLFPDKMK
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: TGT_JANSC
Sequence: MTRASSFRLDATSGKARTGVIQTPRGDIRTPAFMPVGTAATVKAMMPESVAATGADILLGNTYHLMLRPTAERIANLGGLHSFMNWDKPILTDSGGFQVMSLADLRKLTEEGVTFRSHIDGSKHLLSPERSMEIQKLLGSDIVMCFDECPALPADRKALDDSMRLSMRWAARSKEAFGDRPGYALFGIQQGGLEEDLREESAKALREIGFDGYAVGGLAVGEGQAAMFGCLDFAPDQLPTDKPRYLMGVGKPDDIVGAVKRGIDMMDCVLPSRSGRTGQAWTRRGQVNIKNARHADDPRPLDEDCTCPACRNYSRAYLHHVFRAQEMISGMLLTWHNLHYYQELMQTMRDAIAANDFAGFEARFHADRAEGDIVPL
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: CH60_RICRO
Sequence: MATKLIKHGSKAREQMLEGIDILADAVKVTLGPKGRNVLIEQSFGSPKITKDGVTVAKSIELKDKIRNAGAQLLKSAATKAAEVAGDGTTTATVLARALAREGNKLVAAGYNPMDLKRGMDLAVNAVVEEIKKSSKKINSQEEIAQVGTISSNGDKEIGEKIAKAMEEVGKEGVITVEEAKNFSFDVEVVKGMMFDRGYLSPYFVTNSEKMVAELENPFILLFEKKLSNLQPMLPILEAVVQSQRPLLIIAEDVEGEALATLVVNRLRGGLKVAAVKAPGFGDRRKAMMEDIAILTKGELITEDLGMKLENVSIKSLGTAKRVTISKENTVIVDGNGDKKNIEDRVLQIKSQIAETTSDYDKEKLQERLAKLSGGVAVLKVGGATEVEVKERKDRVEDALAATRAAVEEGVVAGGGVTLLHASQPLTKLKVENKDQQAGIEIVIEALKDPLKQIVENAGENGGVVVGKLLEHKDKNYGFNAQDMQYVDMIKAGIIDPAKVVRTALQDAASVASLIITTETLIVDEPSDKAEPMPMRGGMGGMGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVC_RHOPT
Sequence: MTAVSIRRPIRILGIDPGLRRTGWGVVDSDGNRLVYVACGSVEPRDTLPLAERLLAIHDGLAKVLAAHAPAEAAVEQTFVNKDGAATLKLGQARGVAMLVPAMHGLLVAEYAPNLVKKTVVGAGHADKTQIQMMLKILLPKADPKTADAADALAIAITHAHHRGAAQRLKAVGA
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: HSLU_SALG2
Sequence: MSEMTPREIVSELNKHIIGQDNAKRSVAIALRNRWRRMQLDEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAKNNWGQAEQQQEPSAARQTFRKKLREGQLDDKEIEINLAAAPMGVEIMAPPGMEEMTSQLQSMFQNLGGQKQKPRKLKIKDAMKLLVEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKRGETSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQVAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASVTVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNETTENIGARRLHTVLERLMEEISYNASDLHGQNITIDAEYVSKHLDALVADEDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Heat shock protein HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KPBA_DROME
Sequence: MRSRSNSGVRLDYYQRIVHRLILAHQEPVTGLFPASNVNSHAWIRDNVYCILAVWGLSMAYKKIADQDEDRAKCYELEQSCVKLMRGLLMAMMNQKDKVEKFKMTQSPYDSLHAKYSSKNGLPVVDDNEWGHLQIDAVSLYLLILAQMTASGLQIVFSLDEVSFIQNLVFYIESAYSIPDYGIWERGDKTNHGEPELNASSIGMAKAALEAMNELDLFGARGGPASVIHVLADEAHKCQAVLQSMLPRESNSKELDSGLLCVIGFPAFAVDDAQLIHNTKDAILSRLQGKYGCKRFLRDGYRTPKEDPSRLYYERWELRMFENIECEWPLFYCYLILFHAFQSDKRAVEEYASRLEKIMVRSEDGILLVPESYAVPQDLVGFEYQKPGSQVREVVGRCPFLWGQSLFILGRLLQEGFLAVGELDPLNRRLGAQKKPDVVVQVVIIAEDNEIRDKLAEHDLHVQTIAEVAPIEVQPARVLSHLYTYLGRNRKLGLSGRKSRDVGILSTSKLYSLKDRIFAFTPQFADLSRFYIASDNELMIDILKGEINFLKSAWDLLGRPLVTLVLKRIHLDQDKIPLAMIQTMRKLKSGYINGTRVMLGSLKDFLNTSAITDLSFLGSTEDGYPDRLHPDVQTYLDEHLLRSFSNRSTMNLRGGQLRPRTLRRRMSCKGAIKKTRSINVDSDNLGMEGPSPLTERRLSSIVPPPWLQANKQSHVSVFATTPEEGPTSSPLSLGNDLIRENIYPVDPHHSRSAIDRRSEFVRQQEMPKILIQRHRAETNFADTEVEELIAMLRETENLEEQGDILQYLVDTQGLDFNTAGLGFKNKSEENATPNANNAGMLEEGRVVTVRDLLKGLYEKACQQKLWGLVRHTAGMLGKRVEDLAKAVTDLLVRQKQVTVGMPPNNEHTITAPLPEVELRQLIHDAYGDDESTAMLTQELMVYLAMFIRTEPQLFHEMLRLRVGLIIQVMAKELSRTLNCDGEAASEHLLNLSPFEMKNLLYHILSGKEFAVSSVARGNLSIVSCKSSRVSKKSQIGLGDPEGEDALIATIDDRQGQWLRRRRLDGALNRVPRDFYSRVWTVLEKCQGLAIEGRVLQQSLTQEMTPGELKFALEVETALNQIPQPEYRQLVVEALMVLTLVTEHNMVPSLGGVIYVEHLVHKANQLFLEDQRKVQGDATLCCAKIKDGKEQQQAASGMLLCGGAAYICQHLYDSAPSGSYGTMTYMSRAVALVLDCVPKHGEMECAIS
What is the function of this protein?
Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.  The alpha chain may bind calmodulin (By similarity).
What are the official names of this protein?
Probable phosphorylase b kinase regulatory subunit alpha, Phosphorylase kinase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the phosphorylase b kinase regulatory chain family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: ENO_NOCFA
Sequence: MAIIEQVGAREILDSRGNPTVEVEIALDDGTLTRAAVPSGASTGEHEAVELRDGGDRYNGKGVLKAVEGVLDEIAPAVIGLDAVEQRTVDQVLLDLDGTPDKSRLGANALLGVSLAVARAAAESSGLELFRYLGGPNAHVLPVPMMNILNGGAHADTGVDVQEFMVAPIGAPTFKESLRWGAEVYHALKAVLKSKGLSTGLGDEGGFAPDVAGTREALDLIAQAIAKTGLKLGSDVALALDVAATEFYTSGSGYKFEGTVRSAEEMAQFYSELLGAYPLVSIEDPLSEDDWDGWVALTDQIGDKIQLVGDDLFVTNPERLEDGIAKGAANALLVKVNQIGTLTETLDAVELAHRNGYKTMMSHRSGETEDTTIADLAVAVGSGQIKTGAPARSERVAKYNQLLRIEDALGDSARYAGDVAFPRFVFDG
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: CTF18_SCHPO
Sequence: MDSIPNEDDLEKLLVAEQNVPYGKNYESFEDEENYLLELRNANALENLEHRSIPNDLFHSSQPVGSPTRNGDDIPSTLDLYSSDNAAIDTDISEDETINQRHAPQTDYRYPNTSANPKMGLEESMDIDMPSIDLDISNAAAFPRDSNLLFRNYNSHTKTSEKGSPVNFEKENQDSNVLFSTGRTSVLHIDAEQSQTNNTVTPLKDDALSLFSFENDVNGAVNDNSLDQKLSASKNSQRVSLPFFSKIELDEGSSFSGPKISARTSSGKIIYFPKKKNRHSDGLLLQPKRLADEISQVNEIGKDFNQDLLNSVRIWSENFLIVSKEKSVALKTEKLDSLQITNCTTKPQSQKLWVDTYRPQLFRDLLGDERVHRAAMHWIKAWDPCVFGKSRLQPSKSMRFNPRFTNITSDSDRPDKRIMMLTGLAGAGKTTLAHVIAHQAGYKVLEINASDDRTAHTVHEKVSSAISNHSALSSQPTCVIVDEIDGGDPAFVRALLSLLESDEKATEYSQAGNSKKKKKFKKLCRPIICICNDLYTPALRPLRPYAQIIYFRPPPQASLVGRLRTICRNENIAVDSRSLTLLTDIYNSDIRSCINSLQLLSLNNKRIDSETIKLLQPKSNSFSTSSLIQSLFLQLDNKQIRAIEASQPTYSHLDALLARIDGANDSESVLMNCFHTYLDLPFTDSLLSKPALTSEWLYFFDQLHSQCYKGNYELWRYIPYSIIHFHYLYATPEKCRLPHPPRSDLEALKLYRTRKEILDSFISTLNAYENQMHGERSILLELIRTILITINPTLKQKEDSMPRSALPSKIEHAINILNHYNLRFQQLPVGDGNYVYRLEPPLDELVWDAPTSSYSVRQMLSQELLKKRLADIKKQTLTDNPTSSNSSRKRKDFNSGKAIKRDFFGRIISEPKSEAVTSNNAALNTGDHPVSIKHAINIKFHDGFSNAVRKPISLNEILNF
What is the function of this protein?
Essential for the fidelity of chromosome transmission.  Required for the DNA replication block checkpoint.  Replication factor C (RFC) complex has an essential but redundant activity in sister chromatid cohesion establishment.  Acts as a PCNA loader, loading PCNA onto primed templates.  An RFC-like complex (ctf18-RFC) is formed where ctf18 replaces rfc1 in the RFC complex along with the association of dcc1 and ctf8.  This complex is required for efficient establishment of chromosome cohesion during S-phase.
What are the official names of this protein?
Chromosome transmission fidelity protein 18.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family. CTF18 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: UTS2_MOUSE
Sequence: MDRVPFCCLLFIGLLNPLLSLPVTDTGERTLQLPVLEEDALRALEELERMALLQTLRQTMGTEAGESPGEAGPSTETPTPRGSMRKAFAGQNSNTVLSRLLARTRKQHKQHGAAPECFWKYCI
What is the function of this protein?
Highly potent vasoconstrictor.
What are the official names of this protein?
Urotensin-2, Urotensin II, U-II, UII.
What is the protein family that this protein belongs to?
Belongs to the urotensin-2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: GPDA_ESCF3
Sequence: MNQRNASMTVIGAGSYGTALAITLARNGHEVVLWGHDPEHIATLKRDRCNAAFLPDVPFPDTLHLESDLATALAASRNILVVVPSHVFGEVLRQIKPLMRPDARLVWATKGLEAETGRLLQDVAREALGDQIPLAVISGPTFAKELAAGLPTAISLASTDQTFADDLQQLLHCGKSFRVYSNPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLAEMSRLGAALGADPATFMGMAGLGDLVLTCTDNQSRNRRFGMMLGQGMDVQSAQEKIGQVVEGYRNTKEVRELAHRFGVEMPITEEIYQVLYCGKNAREAALTLLGRARKDERSSH
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDC6_YEAST
Sequence: MSEITLGKYLFERLKQVNVNTIFGLPGDFNLSLLDKIYEVDGLRWAGNANELNAAYAADGYARIKGLSVLVTTFGVGELSALNGIAGSYAEHVGVLHVVGVPSISAQAKQLLLHHTLGNGDFTVFHRMSANISETTSMITDIATAPSEIDRLIRTTFITQRPSYLGLPANLVDLKVPGSLLEKPIDLSLKPNDPEAEKEVIDTVLELIQNSKNPVILSDACASRHNVKKETQKLIDLTQFPAFVTPLGKGSIDEQHPRYGGVYVGTLSKQDVKQAVESADLILSVGALLSDFNTGSFSYSYKTKNVVEFHSDYVKVKNATFLGVQMKFALQNLLKVIPDVVKGYKSVPVPTKTPANKGVPASTPLKQEWLWNELSKFLQEGDVIISETGTSAFGINQTIFPKDAYGISQVLWGSIGFTTGATLGAAFAAEEIDPNKRVILFIGDGSLQLTVQEISTMIRWGLKPYLFVLNNDGYTIEKLIHGPHAEYNEIQTWDHLALLPAFGAKKYENHKIATTGEWDALTTDSEFQKNSVIRLIELKLPVFDAPESLIKQAQLTAATNAKQ
What is the function of this protein?
Minor of three pyruvate decarboxylases (PDC1, PDC5, PDC6) implicated in the nonoxidative conversion of pyruvate to acetaldehyde and carbon dioxide during alcoholic fermentation.  Most of the produced acetaldehyde is subsequently reduced to ethanol, but some is required for cytosolic acetyl-CoA production for biosynthetic pathways.  The enzyme is also one of five 2-oxo acid decarboxylases (PDC1, PDC5, PDC6, ARO10, and THI3) able to decarboxylate more complex 2-oxo acids (alpha-keto-acids) than pyruvate, which seem mainly involved in amino acid catabolism.  Here the enzyme catalyzes the decarboxylation of amino acids, which, in a first step, have been transaminated to the corresponding 2-oxo acids.  In a third step, the resulting aldehydes are reduced to alcohols, collectively referred to as fusel oils or alcohols.  Its preferred substrates are the transaminated amino acids derived from threonine (2-oxobutanoate), norvaline (2-oxopentanoate), valine (3-methyl-2-oxobutanoate, also alpha-keto-isovalerate), isoleucine ((3S)-3-methyl-2-oxopentanoate, also alpha-keto-beta-methylvalerate), phenylalanine (phenylpyruvate), and tryptophan (3-(indol-3-yl)pyruvate), whereas transaminated leucine is no substrate.  In a side-reaction the carbanionic intermediate (or active aldehyde) generated by decarboxylation or by activation of an aldehyde can react with an aldehyde via condensation (or carboligation) yielding a 2-hydroxy ketone, collectively called acyloins.  The expression level of this protein in the presence of fermentable carbon sources is so low that it cannot compensate for the other two pyruvate decarboxylases to sustain fermentation.
What are the official names of this protein?
Pyruvate decarboxylase isozyme 3, Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase, 2ODC.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNC50_HUMAN
Sequence: MLPSTSVNSLVQGNGVLNSRDAARHTAGAKRYKYLRRLFRFRQMDFEFAAWQMLYLFTSPQRVYRNFHYRKQTKDQWARDDPAFLVLLSIWLCVSTIGFGFVLDMGFFETIKLLLWVVLIDCVGVGLLIATLMWFISNKYLVKRQSRDYDVEWGYAFDVHLNAFYPLLVILHFIQLFFINHVILTDTFIGYLVGNTLWLVAVGYYIYVTFLGYSALPFLKNTVILLYPFAPLILLYGLSLALGWNFTHTLCSFYKYRVK
What is the function of this protein?
Involved in the cell surface expression of neuronal nicotinic receptors (By similarity).  Binds RNA (By similarity).
What are the official names of this protein?
Protein unc-50 homolog, Periodontal ligament-specific protein 22, PDLs22, Protein GMH1 homolog, hGMH1, Uncoordinated-like protein.
What is the protein family that this protein belongs to?
Belongs to the unc-50 family.
What are the subcellular locations of this protein?
Nucleus inner membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: RL24_ALIB4
Sequence: MAIKLKIKKGDTVKIIAGDDKGKTGEVLAVLPKEKKVIVKDCKVAKKTVKPDQEKNPEGGFVNKEMPIDISNVAKVEGE
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.