PharMolix/UniProtQA huggingface dataset:
Protein: FTSY_METH1
Sequence: MGFWSNLKDKLFGTKEERIAKKQAKIEAKEQRQLEKELIKKNKLNTYIAGLSKSNSSFNEHIKELQNKHNKIDEEFFEDLEEMLIMSDISIKLVQIIINECKKEVRNENITDPKLINEIIADKLFTIYTSNSVVDTTLNIKDNRLNVILVVGVNGSGKTTSISKIAKKLIDEGKKVLIAAGDTFRAAAVEQLEIWAKRVGADIVTPNENEVDPAAVVYRAIDIAKSKKYDILIVDTAGRLQNKVNLMNELAKINRVLASKIPDAPHESLLVLDATTGQNGVIQARVFKESTPLTGIILTKMDGTSKGGIVLTIKDEIGLFVKYIGLGEKVDDLAEFDLDSYIYGLTKGINE
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
What are the official names of this protein?
Signal recognition particle receptor FtsY, SRP receptor.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. FtsY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm.
Protein: TYRA_STAAM
Sequence: MTTVLFVGLGLIGGSLASNIKYHNPNTNIIAYDADTSQLDKAKSIGIINEKCLNYSEAIKKADVIIYATPVAITNKYLSELIDMPTKPGVIVSDTGSTKAMIQQHESNLLKHNIHLVSGHPMAGSHKSGVLNAKKHLFENAYYILVYNEPRNEQAANTLKELLSPTLAKFIVTTAEEHDYVTSVVSHLPHIVASSLVHVSQKNGQEHHLVNKLAAGGFRDITRIASSNAQMWKDITLSNKTYILEMIRQLKSQFQDLERLIESNDSEKLLSFFAQAKSYRDALPAKQLGGLNTAYDLYVDIPDESGMISKVTYIMSLHNISISNLRILEVREDIYGALKISFKNPTDRERGMQALSDFDCYIQ
What are the official names of this protein?
Prephenate dehydrogenase, PDH.
What is the protein family that this protein belongs to?
Belongs to the prephenate/arogenate dehydrogenase family.
Protein: VIRBA_BRUSU
Sequence: MTQENIPVQPGTLDGERGLPTVNENGSGRTRKVLLFLFVVGFIVVLLLLLVFHMRGNAENNHHSDKTMVQTSTVPMRTFKLPPPPPPPPPAPPEPPAPPPAPAMPIAEPAAAALSLPPLPDDTPAKDDVLDKSASALMVVTKSSGDTNAQTAGDTVVQTTNARIQALLDSQKNTKQDAGSLGTLLHGTQTDARMASLLRNRDFLLAKGSIINCALQTRLDSTVPGMAACVVTRNMYSDNGKVLLIERGSTISGEYDANVKQGMARIYVLWTRVKTPNGVVIDLDSPGADPLGGAGLPGYIDSHFWKRFGGALMLSTIETLGRYATQKVGGGGSNQINLNTGGGESTSNLASTALKDTINIPPTLYKNQGEEIGIYIARDLDFSSVYDVKPK
What is the function of this protein?
The VirB system could be required for the establishment of the replication niche in the host.
What are the official names of this protein?
Type IV secretion system protein virB10.
What is the protein family that this protein belongs to?
Belongs to the TrbI/VirB10 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: ISPE_DINSH
Sequence: MSPPTEGRAPGSRPIAGFAPAKINLTLHVTGQRGDGYHLLDSLVVFADIGDRLVLDPDAALGLTVSGPRAAGVPTGPENLILKAAAHLGAVRGAIHLEKHLPAAAGIGGGSSDAATALRLHAQAMGRALPDDGAALGADVPVCLRGKATRMSGIGEALTPVAGLPPLPAVLVNPGVDVPTPAVFRGLRQKENPPMPADLPGFATPTDCARWLATQRNDLEPPARAAAPVIDSVLAEIAGDPDCLLARMSGSGATCFGLFETPAQAQAAAETLSTRHPDWWVAPTVLR
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: YO08A_YEAST
Sequence: MWRSYLVFLFFMTPRIQTYCPVPVLRSMAVLNIISPLIIFVSPIKKQDSLHSSACYANLTLVEKLQLWHSMSND
What is the function of this protein?
May be involved in the regulation of telomere length.
What are the official names of this protein?
Uncharacterized protein YOR008C-A.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: ZN687_HUMAN
Sequence: MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGPGKPEPGVGSESEDTAAASAGDGPGVPAQASDHGLPPPDISVVSVIVKNTVCPEQSEALAGGSAGDGAQAAGVTKEGPVGPHRMQNGFGSPEPSLPGTPHSPAPPSGGTWKEKGMEGKTPLDLFAHFGPEPGDHSDPLPPSAPSPTREGALTPPPFPSSFELAQENGPGMQPPVSSPPLGALKQESCSPHHPQVLAQQGSGSSPKATDIPASASPPPVAGVPFFKQSPGHQSPLASPKVPVCQPLKEEDDDEGPVDKSSPGSPQSPSSGAEAADEDSNDSPASSSSRPLKVRIKTIKTSCGNITRTVTQVPSDPDPPAPLAEGAFLAEASLLKLSPATPTSEGPKVVSVQLGDGTRLKGTVLPVATIQNASTAMLMAASVARKAVVLPGGTATSPKMIAKNVLGLVPQALPKADGRAGLGTGGQKVNGASVVMVQPSKTATGPSTGGGTVISRTQSSLVEAFNKILNSKNLLPAYRPNLSPPAEAGLALPPTGYRCLECGDAFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMRPVALDQMVGQPDITPLLPVAVPPVSGPLALPALGKGEGAITSSAITTVAAEAPVLPLSTEPPAAPATSAYTCFRCLECKEQCRDKAGMAAHFQQLGPPAPGATSNVCPTCPMMLPNRCSFSAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHVSRRVGYRCPSCSVVFGGVNSIKSHIQTSHCEVFHKCPICPMAFKSGPSAHAHLYSQHPSFQTQQAKLIYKCAMCDTVFTHKPLLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRLEETAGKGAGGALLTPKTEPEELAVSQGGAAPATEESSSSSEEEEVPSSPEPPRPAKRPRRELGSKGLKGGGGGPGGWTCGLCHSWFPERDEYVAHMKKEHGKSVKKFPCRLCERSFCSAPSLRRHVRVNHEGIKRVYPCRYCTEGKRTFSSRLILEKHVQVRHGLQLGAQSPGRGTTLARGSSARAQGPGRKRRQSSDSCSEEPDSTTPPAKSPRGGPGSGGHGPLRYRSSSSTEQSLMMGLRVEDGAQQCLDCGLCFASPGSLSRHRFISHKKRRGVGKASALGLGDGEEEAPPSRSDPDGGDSPLPASGGPLTCKVCGKSCDSPLNLKTHFRTHGMAFIRARQGAVGDN
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 687.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
Protein: SOGA1_MOUSE
Sequence: MLEMRDVYMEEDVYQLQELRQQLDQASKTCRILQYRLRKAERRSLRAAQTGQVDGELIRGLEQDVKVSKDISMRLHKELEVVEKKRMRLEEENEGLRQRLIETELAKQVLQTELDRPREHSLKKRGTRSLGKTDKKPTAQEDSADLKCQLHFAKEESALMCKKLTKLAKENDSMKEELLKYRSLYGDLDAALSAEELADAPHSRETELKVHLKLVEEEANLLSRRIVELEVENRGLRAEMDDMKDHGGGGGPEARLAFSSLGGECGESLAELRRHLQFVEEEAELLRRSSAELEDQNKLLLNELAKYRSEHELDVTLSEDSCSVLSEPSQEELAAAKLQIGELSGKVKKLQYENRVLLSNLQRCDLASCQSTRPMLETDAEAGDSAQCVPAPLGETLEPHAARLCRAREAEALPGLREQAALVSKAIDVLVADANGFSVGLRLCLDNECADLRLHEAPDNSEGPRDAKLIHAILVRLSVLQQELNAFTRKADVALGSSGKEQPEPFPALPALGSQGPAKEIMLSKDLGSDFQPPDFRDLLEWEPRIREAFRTGDLESKPDPSRNFRPYRAEDNDSYASEIKDLQLVLAEAHDSLRGLQEQLSQERQLRKEEADSFNQKMVQLKEDQQRALLRREFELQSLSLQRRLEQKFWSQEKNILVQESQQFKHNFLLLFMKLRWFLKRWRQGKVLPSEEDDFLEVNSMKELYLLMEEEEMNAQHSDNKACTGESWTQNTPNECIKTLADMKVTLKELCWLLQDERRGLTELQQQFAKAKATWETERAELKGHASQMELKAGKGASERPGPDWKAALQREREEQQHLLAESYSAVMELTRQLQLSERHWSQEKLQLVERLQGEKQQVEQQVKELQNRLSQLQKAAEPWVLKHSDMEKQDNSWKEARSEKTHDKEGVSEAELGGTGLKRTKSVSSMSEFESLLDCSPYLAGGDARNKKLPNGPAFAFVSTEPVEPEKDAKEKAGLSTRDCSHIGSLACQEPAGRQMQRSYTAPDKTGIRVYYSPPVARRLGVPVVHDKEGKILIEPGFLFTTAKPKESAEADGLAESSYSRWLCNFSRQRLDGGSGASTSGSGPAFPALHDFEMSGNMSDDMKEITNCVRQAMRSGSLERKVKNTSSQTVGVATVGTQTIRTVSVGLQTDPPRSSLHSKSWSPRSSSLVSVRSKQISSSLDKVHSRIERPCCSPKYGSPKLQRRSVSKLDSTKDRSLWNLHQGKQNGSAWARSTTTRDSPVLRNINDGLSSLFSVVEHSGSTESVWKLGMSEARTKPEPPKYGIVQEFFRNVCGRAPSPTTAAGEESCKKPEPLSPASYHQPEGVSRILNKKAAKAGGSEEVRPTMLSQVGKDGILRDGDGSLILPSEDAVCDCSAQSLASCFIRPSRNTIRHSPSKCRLHPSESGWGGEERAAPQ
What is the function of this protein?
Regulates autophagy by playing a role in the reduction of glucose production in an adiponectin- and insulin-dependent manner.
What are the official names of this protein?
Protein SOGA1, SOGA family member 1, Suppressor of glucose by autophagy, Suppressor of glucose, autophagy-associated protein 1.
What is the protein family that this protein belongs to?
Belongs to the SOGA family.
What are the subcellular locations of this protein?
[C-terminal 80 kDa form]: Secreted. Note=Secreted in primary hepatocyte-conditioned media.
Protein: RSMA_ZYMMO
Sequence: MLDQTLEPLRAVIARHGLSADKRLGQNFLLDSQLLDRIARVPGDLTQKTVYEVGPGPGGLTRALLKAGAKVTAVERDRRCLPALAELSAHFPDQLQVISGDAMEIDEAAVLGEHVHIVANLPYNVGTALLIRWLTAKTWQPWWSSLTLMFQKEVAERITAKVGTPHYGRLSVLAQWRSEAKLSFPVHRSAFVPPPKVMSAVVHLTPKDQPEGLSLGTLEKITAAAFNQRRKMLRQSLKNIEHMMEALELAGIDATRRPETVSVAEFIAIGRHWEKLSA
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRC_RICFE
Sequence: MTLEITGSELIKSKLIDAPERCGVYRMFDVNKQVIYVGKAKNLKKRLTNYIKSDLDNKTLRMIANTCFLEYSITNSEVEALLLEAQLIKKFQPKFNILLKDDKSFPFIKLRLDHDFPQLLKYRGKTLNSGKFFGPFASSTEVNTTLTELQKIFKLRSCTDNYFNSRTRPCLQYEIKRCYAPCVGKINKEDYRDLVAQVKDFLQGRTKELQENLSKKMEELSSQMRFEEAAEIRDRIKALSYVQLKAGVSDIVKDADIIAIVEKNGHYCVEVFLYRAGQACGNIPYFPTSTENSTKEEVLEYFLLQFYQKQQVPAEIIINHEINDKENVIEAIKKINNITKLNIIIPISGGKAKLVQNAAINALFSLEQYLKKFAKNQEIMLEIKELFGLSEISERIEIYDNSHIQGKFAVGVMVVAGKAGFDKKEYRVFSLSSRNSSLSSHASPLSSRNLIAGSSSYFLDPVVKPRDDIVGDDYEMLRQVLTRRLTRLKNEPHKLPSLMIIDGGRGHLGVVKEVMDKFEMNIPFVCMSKGVDRNAGLEQFHMTGKEVFTLDKNLPIMKYLQILRDEAHNFAIKNHRLGRSRAIKLSSLDDIEGIGETRKKALLHYFGSYKAVCDATIDELTKVNGINKSLAEMIFRTLHKSL
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_PETHA
Sequence: MTNIRKTHPLIKIVNHSFIDLPTPSNISAWWNFGSLLGLCLIIQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYIHANGASMFFICLYLHVGRGLYYGSYTYFETWNIGVILLFTIMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALVMVHLLFFHETGSNNPSGLISDSDKVPFHPYFTIKDILGALLLTLSLMLLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILMLFPILHMSKQRGMMFRPLSQCLFWILAADLFTLTWIGGQPVEHPFIIIGQTASILYFTIILIILPLASMLENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MURC_OENOB
Sequence: MTNYYFIGIKGTGMASLALILHDQGNKVLGSDIDKETFTQFPLVKAGIQITDFDPDLIKSNYVVVKGNAFSDDHPQVLAAKKVGAKLLTYPQAVEEVIRRHFSIAVSGAHGKTSTTSLLAHILSNFESTSYLIGDGVGKGVFSSKYFVVEADEYDRHFQPFTPDVAIITNIDWDHPDYYKSLDDVKSAFSEFADHVKKIIFAYGEDPEIKKIKPKTARILSYGFEKSDYFCANNIDKRTEGSYFSLSKGGRKLGDFFATIEGDHGILDTTAAIAVADYLGFSVDQIQKGLLTYQGAKRRFNISQVADLTIVDDYAHHPTEIKATIDAARQKFPNKRLVAVFQPHTYTRVNAFKDEYVNALKSADKVYITPIFGSLREKAGNAKSEDILDKLPNAGAIISESNAYDKLSAEHGSVLVFMGAGDIEKYEDALKKGFE
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_ERYLH
Sequence: MSVDAETKTKIIKDNARDKNDTGSPEVQVAILTTRIKNLTEHFKDHHKDNHSRRGLLQMVNKRRSLLAYLKKKDVERYNALIQKLGLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: ACSF2_SYNY3
Sequence: MVSTTLPTQLETIRPGIKAPVKETLLTPRFYTTDFDKVANLVLTLQDEEIEAALEELRADYNRYHFVRNDDFKRSFDHIDGATRLAFIDFLERSCTSEFSGFLLFKELSRRLKNRSPKLAEAFHLLARDEARHAGFINKAMADFGLSLDLRYLTQKRTYTFFPPEWVIYTVYLSEKIGYWRYILMFRHLEKNPDHNIYPLFNYFECWCQDENRHGDFFKALLRSQTALWKTWQSRLWSRFFLLTVFVTHTLTVFERTDFYQSVGLDAKQYNVDVVTNTNATAARAFPEVLDTDNPKFFPRLEACASANEKLTAIANSEAPKLAKFCQKAPWIAVIIWQMICIFLQKPVDAEARRGMVC
What is the function of this protein?
Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis.  Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME).
What are the official names of this protein?
Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase 2, Mg-protoporphyrin IX monomethyl ester oxidative cyclase 2.
What is the protein family that this protein belongs to?
Belongs to the AcsF family.
Protein: METE_NEIMF
Sequence: MTTLHFSGFPRVGAFRELKFAQEKYWRKEISEQELLAVAKDLREKNWKHQAAANADFVAVGDFTFYDHILDLQVATGAIPARFGFDSQNLSLEQFFQLARGNKDQFAIEMTKWFDTNYHYLVPEFHADTEFKANAKHYVQQLQEAQALGLKAKPTVVGPLTFLWVGKEKGTVEFNRLSLLQKLLPVYVEILNALVEAGAEWIQIDEPALTVDLPKEWVEAYKDVYATLSKVSAKILLSTYFGSVAEHAALLKSLPVDGLHIDLVRAPEQLDAFADYDKVLSAGIIDGRNIWRANLNKVLETVEPLQAKLGDRLWISSSCSLLHTPFDLSVEEKLKANKPDLYSWLAFTLQKTQELRVLKAALNEGRDSVAEELAASQAAADSRANSSEIHRADVAKRLADLPANADQRKSPFADRIKAQQAWLNLPLLPTTNIGSFPQTTEIRQARAAFKKGELSAADYEAAMKKEIALVVEEQEKLDLDVLVHGEAERNDMVEYFGELLSGFAFTQYGWVQSYGSRCVKPPIIFGDVSRPEAMTVAWSTYAQSLTKRPMKGMLTGPVTILQWSFVRNDIPRSTVCKQIALALNDEVLDLEKAGIKVIQIDEPAIREGLPLKRADWDAYLNWAGESFRLSSAGCEDSTQIHTHMCYSEFNDILPAIAAMDADVITIETSRSDMELLTAFGEFKYPNDIGPGVYDIHSPRVPTEAEVEHLLRKAIEVVPVERLWVNPDCGLKTRGWKETLEQLQVMMNVTHKLRAELAK
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: TYSY_ACIAC
Sequence: MNAPARPVRSQYEDFMRHVYTHGVAKGDRTGTGTRSVFGYQMRFDLNEGFPLVTTKKVHLKSIITELLWFLTGSSSNHWLKERGVTIWDEWAREDGDLGPVYGVQWRSWPTPDGGHIDQISQVVETLRTHPDSRRIIVSAWNVADLDKMALMPCHAFFQFYVAPPQAAGERGKLSCQLYQRSADIFLGVPFNIASYALLTHMMAQQCNLEVGDFIWTGGDCHIYSNHFEQVELQLSRAPHPYPTLHILRRPDSLFDYRFEDFEVRDYAHHPAIKAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTGA_YERP3
Sequence: MISVRRGFSQLWYWGKRGVIGIIALWMAGILIFAFLPVPFSMVMIERQLGAWLTGDFAYVAHSDWVPMDEISPYMVLAVMAAEDQKFPDHWGFDVGAIESALSHNQRNQKRIRGASTLSQQTAKNVFLWDGRSWVRKGLEVGLTAGIELIWTKRRILTVYLNIAEFGNGIFGVEAAARHFFNKPASKLSASEAALLAAVLPNPLRFKVNAPSGYVISRQQWILRQMHQLGGKTFLQENTLD
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: SUMO3_MOUSE
Sequence: MSEEKPKEGVKTENDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGSASRGSVPTPNRCPDLCY
What is the function of this protein?
Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer.  Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process.  Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction.  Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4.  Plays a role in the regulation of sumoylation status of SETX (By similarity).
What are the official names of this protein?
Small ubiquitin-related modifier 3, SUMO-3, SMT3 homolog 1, Ubiquitin-like protein SMT3A, Smt3A.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family. SUMO subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus, PML body.
Protein: STS8_POSPM
Sequence: MLYLPDTMSAWPWQRAINPYFNEVKAASNSWFKSFRAFSPASQKAFDKCDFCLLAALAYPRARKEHLRTGCDLMNLFFVIDEYTDVEDANVCRDMVDIVIDALRRPHDPRPEGEVVLGEIARQFWARAIETASPTSQRRFLETFIAYLESVVLQAADRDCDAEHTVQTYLAQRRDNIGSYPSYAVLELALDIPDDIFYHPAMNELSLYATEMLIIDNDLVSYNREQASGDTNNILFVIMRQFNCSLDHAMAWAAAYHSQLEARFMDAFKRMPSWGLEIDSQVEEYCQGIANWPRGNDCWSFESGRYFGDKGREVQKTRCVPLLPKKERDTSLRQQDVVITSL
What is the function of this protein?
Terpene cyclase that catalyzes the cyclization of farnesyl diphosphate (FPP) to delta(6)-protoilludene.
What are the official names of this protein?
Delta(6)-protoilludene synthase 8, Terpene cyclase 8.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: TRHO_STRPC
Sequence: MSEKIRVLLYYKYVSIENAQEYAAKHLEFCKSIGLKGRILIADEGINGTVSGDYETTQKYMDWVHSDERFADLWFKIDEENQQAFRKMFVRYKKEIVHLGLEDNNFDSDINPLETTGEYLNPKQFKEALLDEDTVVLDTRNDYEYDLGHFRGAIRPDIRNFRELPQWVRDNKDKFMEKRVVVYCTGGVRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGELWDGAMYVFDDRISVPINHVNPTVISKDYFDGTPCERYVNCANPFCNKQIFASEENETKYVRGCSPECRAHERNRYVQENGLSRQEWAERLEAIGESLPEFVGA
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: RL10_BORT9
Sequence: MHAKINPKKVEMFNLLKEFLDGKDSVFFLDYRGLTVATLTELRNRVENEKGELKVVKNNIMKRVLKDKHMEGLDSYLLGPTAVVTAVDEANVIAKIFYEFVKTSSLKVKGGFVLGEVYDEAKLNAYSKLPTKKESISLFMNVLKAPISKLARTLKALSDVKDVKV
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: LEPA_STRE4
Sequence: MNSQELKKRQENIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYKAKNGQDYIFHLIDTPGHVDFTYEVSRSLAACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVIGLDASEAVLASAKSGIGIEDILEQIVEKVPAPSGDVDQPLQALIFDSVYDAYRGVILQVRVVNGMVKPGDTIQMMSNGKTFDVTEVGIFTPKAIGRDFLATGDVGYIAASIKTVADTRVGDTVTLATNPAAEPLHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNITDGDMLEVSNPSEFPDPTKVDSIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVNVIYHIPLAEIVFDFFDKLKSSTRGYASFDYEIAEYRRSQLVKMDILLNGDKVDALSFIVHRAFAYERGKLIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDESKK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RLMD_ALKEH
Sequence: MGRRRRRLPREPFEIAITGLSHEGRGIAHHDERTLFVHGALPGERVRAVYTKRRRSVAEARVVEVVSPAPERIAPHCPHFGVCGGCSLQHLTPERQVELKQSVLMEQFHHMGGVQPERVLAPLTGAPWGYRRKARLAVKHVPRKGGVLVGFREKHSPFVAEMDRCPVLDPRVGERLTELGRLIEGLSIPDRVPQIEVALGDETGALVFRNLAPLTAADLNRLAGFARDSGLAVYQQPGNEATMALVHDPVGRRLDYALPGHGVRLGFRPGDFTQVNAEINRAMVDQALDLLAVEPGQRVLDLFCGLGNFTLPLARRASEVVGVEGAEALVERGRENALRNGLDNVRFYGADLTLAAADQPWATGGFDRVLLDPPRSGAFEVLGLVAALGPKRIVYVSCGPATLARDAGELVHRHGYRLTAAGVMDMFPHTAHVESMAVFQREAQD
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: CTTB2_MUSPF
Sequence: MATDGASCEPDFSRAPEDAEGATAEAAKKEFDVDTLSKSELRMLLSVMEGELEARDLVIEALRARRKEVFIQERYGRFNLNDPFLALQRDYEAGAGEKEKKPVCTNPLSILEAVMAHCRKMQERMSTQLAAAESRQKKLEMEKLQLQGLEQEHKQLAARLEEERGKNKHVVLMLVKECKQLSGKVLDEAQKLEDVLARLEEEKKKTGTLEEQLSAEKRKSTEMEAQMEKQLSEFDTEREQLRAKLHREEAHTTDLKEEIDKMKKMIEQLKRGNDSKPSLSLPRKTKDRRSVSISVGTEGPVTRSVACQTDPAVESIDHVKKLPLTVPVKPPTGSPLVSANTKGNVCPSAALGRPGIDRQASHGDLIVSSLPTVPPPSASKIEENGPSTGSPSSTPPLPNSTAPPTVQTPTIAPQSHAQAAPGHSLHSPCANAALHPGLNPRIQAARFRFQGNANDPDQNGNTTQSPPSRDVSPTSRDSLVAKQLARNTVTQALSRFTSPPAGAPPRPGAPSTGDVGTCPPVGRTSLKTPGVARVDRGNPPPIPPKKPGLSQTPSPPHPQLKVIMDSSRASSAGAKVDNKTMASPPSTLPQGNRVINEENLPKSSSPQLPPKPSIDLTVAPAGCGVSALATSQVGAWPAETPGLSQPACSESSLVIPTTIAFCSSINPVSASSCRTGASDSLLVAASGWSPSLTPLLMSGGPAPLAGRPTLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLNAEAQVNAADKNGFTPLCAAAAQGHFKCVELLIAYNANINHAADEGQTPLYLACKNGNKECIKHLLEAGTDRSVKTRDGWTPVHAAVDAGNVDSLKLLMYHRAPARRNSLHEEEPESGVFDLDQGEESPEGTSKPVIPADLINHADREGWTAAHIAASKGFKDCLEILCKHRGLEPERRDKCNRTAHDVATDDCKHLLENLNALKIPVRISGGESPPGNYGSDDFECENTICALNIRKQTSWEDFSKAVSQALTNHFQAISSDGWRSLEDGTFNNTTDSCIGLSTSSVRSVMLGNVPWSTGQSFSQSPWDFMKKNKAEQVTVFLSGPQEGCLSSVTYTSMIPLQMLQNYLRLVEQYHNVIFHGPEGSLQDYVAHQLALCMKHRQMAAGFTCEIVRAKVDAGFSKEQLGDLFISSACLIPVKQSPMNKKVIIVLENLEKCSLSELLGDFLAPLENRSTESPWILQKGNGTSECYYFHENCFLMGTIAKACLQGSDLLVQQHFRWVQLRWDGEPMQGLLPRFLRRKVMNKFRGQVPSPCDPVCKTVDWALAVWRQLNSCLARLGTPEALLGPEYFLSCPVVPGHAQATVKWMAKLWNAVIAPRVQEAVLSRASVRRQPGLGLTAARSRPSQGQQAVVKVALSILLNKAVLHGCPLQRADLDQHVADFKGGAFPLSIVSSYNSCSRKKGESGAWRKVSTSPRKKSGRFSPPSWSKPGPSEEGIKVKAISQLNYNRNASLSKQKSLENDLSLTLNLEQRLSLGSDDEADLVQELQSMCSSKSESDISKIADSRDDLRSFDSPGNSPAFSATVNPRMPVSPKEVSPFSSHQPTECSNSQSKMELGVSRVKSFLPVPRSKVTQCSQNTKRSSSSSNTRQIEINNNSKEEI
What is the function of this protein?
Regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurons, thus controls dendritic spinogenesis and dendritic spine maintenance.
What are the official names of this protein?
Cortactin-binding protein 2, CortBP2.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Cell projection, dendritic spine. Note=Remains associated with dendritic spines even after glutamate stimulation.
Protein: TRPC_XANP2
Sequence: MTDILKKIEAYKRDEIAVAKHARPLGEIEAAARAAPRVRPFAGAIATSLAEGRTALIAEIKKASPSKGLIRADFDPPALARAYQRGGATCLSVLTDTPSFQGAPEFLGSARAAVDLPVLRKDFMYDTYQVAEARAWGADCILIIMAGVDDLLARDLADAAAAYGMDAIVEVHDDAELERALDLPCRLIGINNRNLRTFETSLETSERLAPRVPKDRIAIGESGIFTPQDVARLAKVGIGTILVGESLMRQEDVASATSQLLAV
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.