PharMolix/UniProtQA huggingface dataset:
Protein: SAC3_YEAST
Sequence: MNTSFGSVVPSTNFNFFKGHGNNDNTSANSTVNNSNFFLNSNETKPSKNVFMVHSTSQKKSQQPLQNLSHSPSYTENKPDKKKKYMINDAKTIQLVGPLISSPDNLGFQKRSHKARELPRFLINQEPQLEKRAFVQDPWDKANQEKMISLEESIDDLNELYETLKKMRNTERSIMEEKGLVDKADSAKDLYDAIVFQGTCLDMCPTFERSRRNVEYTVYSYEKNQPNDKKASRTKALKVFARPAAAAAPPLPSDVRPPHILVKTLDYIVDNLLTTLPESEGFLWDRMRSIRQDFTYQNYSGPEAVDCNERIVRIHLLILHIMVKSNVEFSLQQELEQLHKSLITLSEIYDDVRSSGGTCPNEAEFRAYALLSKIRDPQYDENIQRLPKHIFQDKLVQMALCFRRVISNSAYTERGFVKTENCLNFYARFFQLMQSPSLPLLMGFFLQMHLTDIRFYALRALSHTLNKKHKPIPFIYLENMLLFNNRQEIIEFCNYYSIEIINGDAADLKTLQHYSHKLSETQPLKKTYLTCLERRLQKTTYKGLINGGEDNLASSVYVKDPKKDRIPSIADQSFLMENFQNNYNEKLNQNSSVKPQINTSPKRVATRPNHFPFSQESKQLPQISQSHTLSTNPLLTPQVHGDLSEQKQQQIKTVTDGGSPFVFDQSAQNSTVEASKAHMISTTSNGAYDEKLSSEQEEMRKKEEQRIEEEKTQLKKKQENADKQVITEQIANDLVKEVVNSSVISIVKREFSEANYRKDFIDTMTRELYDAFLHERLYLIYMDSRAELKRNSTLKKKFFEKWQASYSQAKKNRILEEKKREEIKLVSHQLGVPGFKKSTCLFRTPYKGNVNSSFMLSSSDKNLIFSPVNDEFNKFATHLTKISKLWRPLEMQSIYYDNLTKKFPSNSLTPANLFIYAKDWTSLSNRWILSKFNLQTAQDSKKFSNNIISSRIICIDDEYEPSDFSDLQLLIFNTGVTNPDIFDLEMKLKDDGEELIKLITGISLNTNICFSLLIIYWESAENTLSESTIKHLLKLNRISKNYSSVIERIDLMNLTEESPHKCLEDKLSEISHSYVYKLTERGKYDKTLRQKRSLAGIHSRSTQLQTTKDIDQKMKKMLEKEKNKYQQQIGERNTYAHLESHIDASPRSKKRKLPILLSTSHSSQFKTPLASRLNTSGSSTSPPLPSHLAMKFRKNSRVTSLHTVLPVSTPSHSNNIPAASFSGNNTTDIQSQQLIENQKSTSVYLNNVSERILGNQEICQTPINPVTPVLDGADQGKEDIPDSILELKILIDSVKKKVNND
What is the function of this protein?
Component of the SAC3-THP1 complex, which functions in transcription-coupled mRNA export from the nucleus to the cytoplasm.  SAC3-THP1 functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket), by association with components of the nuclear mRNA export machinery (MEX67-MTR2 and SUB2) in the nucleoplasm and the nucleoporin NUP1 at the nuclear basket.
What are the official names of this protein?
Nuclear mRNA export protein SAC3, Leucine permease transcriptional regulator.
What is the protein family that this protein belongs to?
Belongs to the SAC3 family.
What are the subcellular locations of this protein?
Nucleus envelope. Note=Localizes to the nuclear pores.
Protein: GPDA_PHYAS
Sequence: MHITIIGGGAWGATLAQVLTDNNHQVLVYDLNKNYINRINQGMHSIFDLPLKNIQSTSDLEISLLYSDLLVLAVPTKAMRQVLQQIALLSKTPKSFVNVSKGIEPSTFFRVSQIVNQIIPPSLLQNYASLMGPSHAEEVILRKVTLLTAASSDLSFATEIQKIFSNPIYLKIYTSSDLVGNEVCSALKNVLALINGILVAKGFGINSQAALISRGIVEMSRLVTFYHGSFKTVLGLPGLGDLIVTAFSTHSRNFSAGQKIGAGKTYEQIMSESDQVIEGFQSLVAFYQLQSKHQLDLPLIKAAYQLIYECRPFELVFDELMQRPFKSDC
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBLN3_MACFA
Sequence: MLKALFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQETPPAEGTSGATTGVVAASSMATSGVLPGGGFVASAAAVAGPEVQAGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECTIPPYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECETTNECREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAMCRELPQSIVYKYMSIRSDRSVPSDIFQIQATTIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREHIVDLEMLTVSSIGTFRTSSVLRLTIIVGPFSF
What is the function of this protein?
Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways.  May play a role in cell adhesion and migration.  May function as a negative regulator of chondrocyte differentiation.  In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth (By similarity).
What are the official names of this protein?
EGF-containing fibulin-like extracellular matrix protein 1, Fibulin-3, FIBL-3.
What is the protein family that this protein belongs to?
Belongs to the fibulin family.
What are the subcellular locations of this protein?
Secreted, extracellular space. Secreted, extracellular space, extracellular matrix. Note=Localizes to the lamina propria underneath the olfactory epithelium.
Protein: TXD11_MOUSE
Sequence: MSECGGRGGGGGNNSEDAEDEGGGPKGSGSLSPAGAAASLEGRIRRGLRGASLMARQRPELLCGAVALGCALLFALKFTCSRAKDVIIPAKPPVSFFSSRSPVLDLFQGQLDYADHVRQDSEVVVLFFYAPWCGQSIAARAEIEQAASRLSDQVLFVAINCWWNQGKCRKQKHFFYFPVIHLYHRSFGPIEYKGPMSAVYIEKFVRRAMKPLLYIPSQSALLDFLSSYEPGVLGYFEFSGSPQPPGYLTFFTSALHSLKKDYLGTVRFGVITDKHLARLVSLVHSGSVYLHRHFNTSLVFPREVMNFTAENIYKWASENQETLFRWLQPHGGKSLLLNNELKKGPALFLFIPFDPLAERHPLLDEITEVALEYNNCHGDQVVERLLQHLRRVEAPVLQSLAPELPASLPDTQLMAASPCCNTVVLPQGPALSRTHNVCELCVNQTVGGTRPSSVSVPQCSFFEMAAALDSFYLKEQTFYHVVSGSIECSNFLTSYSPFSYYTACCRTISRGMASFTGSEQNVLTAPAIEFSSLEKSCEATAPSSIPHIEENRYRFPQVGLTSTAFTGLSCRTNKTLNIYLLDSNLFWLYAERLGAPSSAPVKEFATIVDVKEESHYILDPKQALMKFTLESFIQNFSVLYSPLKRHLTGSDSAQFPTQHLITEVTTDTFWEVTLRKQDVLLLYYTQWCGFCPSLNHIFIQLARLLPEDTFTVARIDVSQNDLPWEFMVDRLPTVLFFPCNRKDLSVKYPGDLPITLPNLLRFILHHSDAASAPQDPGISPPTQDCVQSKAVLQREHISHVENAMQKLRSEMSSLRRTQEQVEGRLLSARRDGHRLLRRQRTLEQQHRLLRRHSQKLQALYLKKARELQELARASGTPLPEHTWLKILVATMERELEGQGGAKEPAPLGKARPNHSKSMGTTQLPGDTPPPSTTSSTLASETKHENRTD
What is the function of this protein?
May act as a redox regulator involved in DUOX proteins folding.  The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H(2)O(2) generating system.  It is however not sufficient to assist DUOX1 and DUOX2 in H(2)O(2) generation (By similarity).
What are the official names of this protein?
Thioredoxin domain-containing protein 11.
What is the protein family that this protein belongs to?
Belongs to the protein disulfide isomerase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: ALP2_ASPFU
Sequence: MKGYLSLSILPLLVAASPVVVDSIHNGAAPILSSMNAKEVPDSYIVVFKKHVNAESAAAHHSWVQDIHSAQNERVELRKRSLFGFGEEAYLGLKNTFDIAGSLVGYSGHFHEDVIEQVRKHPDVEYIEKDSEVHTMEDPTVEKSAPWGLARISHRDSLSFGTFNKYLYASEGGEGVDAYTIDTGINVDHVDFEGRAQWGKTIPTDDEDADGNGHGTHCSGTIAGRKYGVAKKANLYAVKVLRSSGSGTMSDVVAGVEWAVKSHLKKVKDAKDGKIKGFKGSVANMSLGGGKSRTLEAAVNAGVEAGLHFAVAAGNDNADACNYSPAAAENPITVGASTLQDERAYFSNYGKCTDIFAPGLNILSTWIGSKHAVNTISGTSMASPHIAGLLAYFVSLQPSKDSAFAVDELTPKKLKKDIIAIATQGALTDIPSDTPNLLAWNGGGSSNYTDIIASGGYKVNASVKDRFEGLVHKAEKLLTEELGAIYSEIHDAAVA
What is the function of this protein?
Alkaline protease that allows assimilation of proteinaceous substrates.  Acts as a significant virulence factor in invasive aspergillosis.  Required for regular sporulation.
What are the official names of this protein?
Alkaline protease 2, ALP2, Autophagic serine protease alp2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
Protein: RSMH_SPHAL
Sequence: MTDLPRDPRHDPVLLDEVIAALAIAPGERHVDATFGAGGYTRAMLAAGAEVIACDRDPDAIAGGEALVAEADGRLTLIHGRFGEIDRLLAERGIDAVDGITFDIGVSSMQLDQGERGFSFQKDGPLDMRMAQEGESAADWLNRADEYEIADVLYHYGDERQSRRVARAIVAARPLTRTSELASVVRKALRHPPGAPKDPATKSFQAIRIHINRELDELVAGLAAAERVLRPGGRLAVVSFHSTEDRIVKHFLRERSGGDAAGSRHRPAPTAAARAATFETPARKVRPGKAEEARNPRARSATLRSAVRTAAPAWPGNSMKEAMSC
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLV_SHEWM
Sequence: MTTIVSVRRNNQVVIAGDGQVSLGNTVMKGNAKKVRRLYHNKVLAGFAGGTADAFTLFERFEAKLEMHQGHLMKAAVEMAKDWRSDKMLRKLEALLAVADDTCSLIITGNGDVVQPENDLIAIGSGGNFAQSAATALLENTELTALEIAEKSLTIAGDICVFTNQFKTIEELNY
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_BACFR
Sequence: MKIEKITGREILDSRGNPTVEVDVVLESGIMGRASVPSGASTGEHEALELRDGDKHRYGGKGVQKAVENVNKVIAPHLIGMSALDQIGIDHAMLALDGTKTKAKLGANAILGVSLAVAKAAANYLDIPLYRYIGGTNTYVLPVPMMNIINGGSHSDAPIAFQEFMIRPVGASSFKEGLRMGAEVFHALKKVLKDRGLSTAVGDEGGFAPNLEGTEDALNSILAAIKAAGYEPGKDVMIGMDCASSEFYHDGIYDYTKFEGEKGKKRTADEQIDYLEKLINEYPIDSIEDGMSENDWEGWKKLTQRIGDRCQLVGDDLFVTNVDFLAKGIEKGCANSILIKVNQIGSLTETLNAIEMAHRHGYTTVTSHRSGETEDATIADIAVATNSGQIKTGSLSRSDRMAKYNQLLRIEEELGDRAVYGYKRIVVKG
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase, Heme uptake protein A.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: DSBI_SALTI
Sequence: MDFIKGLWRDLRARPVDTLVRWQEQRFLWLLMAIAMGGLIILAHSFFQIYLYMAPCEQCVYIRYAMFVMVIGGVIAAINPKNIVLKLIGCIAAFYGSIMGIKFSIKLNGIHHAVHNADPDSLFGVQGCSTDPTFPFNLPLAEWAPEWFKPTGDCGYDAPIVPDGVTLSSVQQWFVDLYQQSEGWYLLPPWHFMNMAQACMLAFGLCLILLLVMSGAWALKLARGK
What is the function of this protein?
Required for disulfide bond formation in some proteins.  Part of a redox system composed of DsbI and DsbL that mediates formation of an essential disulfide bond in AssT.
What are the official names of this protein?
Protein-disulfide oxidoreductase DsbI.
What is the protein family that this protein belongs to?
Belongs to the DsbB family. DsbI subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CCA_ECOSE
Sequence: MKIYLVGGAVRDALLGLPVKDRDWVVVGSTPQEMLDAGYQQVGRDFPVFLHPQTHEEYALARTERKSGSGYTGFTCYAAPDVTLEDDLKRRDLTINALAQDDNGEIIDPYNGLGDLQNRLLRHVSPAFGEDPLRVLRVARFAARYAHLGFRIADETLTLMREMTHEGELEHLTPERVWKETESALTTRNPQVFFQVLRDCGALRVLFPEIDALFGVPAPARWHPEIDTGIHTLMTLSMAAMLSPQVDVRFATLCHDLGKGLTPPELWPRHHGHGPAGVKLVEQLCQRLRVPNEIRDLARLVAEFHDLIHTFPMLNPKTIVKLFDSIDAWRKPQRVEQLALTSEADVRGRTGFESADYPQGRWLREAWEVAQSVPTKAVVEAGFKGVEIREELTRRRIAAVASWKEQRCPKPD
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: SYC_ACICJ
Sequence: MIQIKLHNTKTRRREPFAPADPAHVKLYVCGPTVYDRAHLGNARTVVVFDTLVRLLRHLFPRVTYVRNITDIDDKINARAAETGETIGEITARTTSWFHEDMAALYCAPPDIEPRATGHIGDIIALIERLIARGHAYAAEGHVLFAVATDAEYGKFSGRSPEELLAGARVDVATYKRDPGDFVLWKPSPPDLPGWDSPWGRGRPGWHIECSAMIHATLGETIDIHGGGADLIFPHHENEIAQSCCAFPGSEFARVWVHAGMLQVDGQKMSKSLGNFRTVQDVLGEAPGEAVRFLLLKTHYRGVLDFSTAALAEAKRELDRFYRALEKHADPAPAATPPAAFIEALADDLNTPGAIAELHALADAAMQGDAASAAGLRAAGMLIGIFNHTADQWFRGEATDDARIDALIAERLAARRNKDFARADAIRAELAAAGILLEDGPGGTTWRRA
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPH_GEOKA
Sequence: MEVIKITPRGYCYGVVDAMVIARNAALDPSLPRPIYILGMIVHNKHVTDAFAEEGIITLDGENRLEILEKIDQGTVIFTAHGVSPEVKKRALEKGLVTIDATCPDVTKTHRLIEQKLADGYDIIYIGKKGHPEPEGAVGINPERIHLVETIDDVERLSIHNERIMVTNQTTMSQWDVADIMAKVKEKYPHVEMHKEICLATQLRQEAVAEQAKEADVTIVVGDPRSNNSNRLAQVSEEIAGTKAYRVADVTEIDINWIKDAKKVAVTAGASTPTPITKEVIDFLEQFDPNDPSTWKRERKVPLQKILPKVKTKKEE
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: MSTO1_HUMAN
Sequence: MAGGAREVLTLQLGHFAGFVGAHWWNQQDAALGRATDSKEPPGELCPDVLYRTGRTLHGQETYTPRLILMDLKGSLSSLKEEGGLYRDKQLDAAIAWQGKLTTHKEELYPKNPYLQDFLSAEGVLSSDGVWRVKSIPNGKGSSPLPTATTPKPLIPTEASIRVWSDFLRVHLHPRSICMIQKYNHDGEAGRLEAFGQGESVLKEPKYQEELEDRLHFYVEECDYLQGFQILCDLHDGFSGVGAKAAELLQDEYSGRGIITWGLLPGPYHRGEAQRNIYRLLNTAFGLVHLTAHSSLVCPLSLGGSLGLRPEPPVSFPYLHYDATLPFHCSAILATALDTVTVPYRLCSSPVSMVHLADMLSFCGKKVVTAGAIIPFPLAPGQSLPDSLMQFGGATPWTPLSACGEPSGTRCFAQSVVLRGIDRACHTSQLTPGTPPPSALHACTTGEEILAQYLQQQQPGVMSSSHLLLTPCRVAPPYPHLFSSCSPPGMVLDGSPKGAAVESIPVFGALCSSSSLHQTLEALARDLTKLDLRRWASFMDAGVEHDDVAELLQELQSLAQCYQGGDSLVD
What is the function of this protein?
Involved in the regulation of mitochondrial distribution and morphology (PubMed:17349998, PubMed:28554942, PubMed:28544275).  Required for mitochondrial fusion and mitochondrial network formation (PubMed:28554942, PubMed:28544275).
What are the official names of this protein?
Protein misato homolog 1.
What is the protein family that this protein belongs to?
Belongs to the misato family.
Protein: ORF11_HHV8P
Sequence: MAQESEQCSRAFAVCSSKRQLGRGEPVWDSVIHPSHIVISNRVPLLLREQNICLPSCPSVGQILHRAYPNFTFDNTHRKQQTETYTAFYAFGDQNNKVRILPTVVESSSSVLIFRLRASVSANIAVGGLKIIILALTLVHAQGVYLRCGKDLSTPHCAPAIVQREVLSSGFEPQFTVTGIPVTSSNLNQCYFLVRKPKSRLAKPFARLSAETTEECRVRSIRLGKTHLRISVTAPAQETPVWGLVTTSFSLTPTAPLAFDRNPYNHETFACNARHYIPVIYSGPKITLAPRGRQVVWHNNSYTSSLPCKVTAIVSNHCCNCDIFLEDSEWRPNKPAPLKLVNTSDHPVILEPDTHIGNALFIIAPKARGLRRLTRLTTKTIELPGGVKIDSRKLQTFRKMYVATGRS
What are the official names of this protein?
Protein ORF11.
Protein: PSD_BRASB
Sequence: MSISNSIRAQIPPIHPEGYPFIGGFALVSLILFWIFTPLGWIGTLLTVWCALFFRDPIRVTPQREGLVVAPADGRISMITRALPPAELGLGDRPLLRVSIFMSVFNVHVNRSPVAGRIEKISYRPGAFINAELDKASEDNERNSLAISTPHGKIGVVQIAGLVARRIVSFVREGQTVGAGERFGLIRFGSRLDVYLPDGTEVLVSEGQTAIAGETILADFDVATPGLTFRSQ
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ATPE_ESCF3
Sequence: MAMTYHLDVVSAEQQMFSGLVEKIQVTGSEGELGIYPGHAPLLTAIKPGMIRIVKQHGHEEFIYLSGGILEVQPGNVTVLADTAIRGQDLDEARAMEAKRKAEEHISSSHGDVDYAQASAELAKAIAQLRVIELTKKAM
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: UPPP4_BACCZ
Sequence: MNWLEAFILGIIQGLTEFLPISSTGHLYLGRHLFQLDEAGLFLDTMLHIGTLLAVFIYYKKEFIYLIKNPFSKLMLLLIVGTIPAVVIGLLFKDFFEDISKTGITIGWEFLVTGFFLYMADKQKNGRKKMDDITYKDAFIIGSFQAAAIFPAISRSGMTIVAALWRKLDRETAAYFSFLLSTPAIVGAIILQFVDVFQGKAESISSTSLIVGTLSAAFFGYIAVSWMIQYLKRHSLKVFAYYVWGLGILILTLQFTDVF
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase 4, Bacitracin resistance protein 4, Undecaprenyl pyrophosphate phosphatase 4.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LTAS_STAAS
Sequence: MSSQKKKISLFAFFLLTVITITLKTYFSYYVDFSLGVKGLVQNLILLMNPYSLVALVLSVFLFFKGKKAFWFMFIGGFLLTFLLYANVVYFRFFSDFLTFSTLNQVGNVESMGGAVSASFKWYDFVYFIDTLVYLFILIFKTKWLDTKAFSKKFVPVVMAASVALFFLNLAFAETDRPELLTRTFDHKYLVKYLGPYNFTVYDGVKTIENNQQKALASEDDLTKVLNYTKQRQTEPNPEYYGVAKKKNIIKIHLESFQTFLINKKVNGKEVTPFLNKLSSGKEQFTYFPNFFHQTGQGKTSDSEFTMDNSLYGLPQGSAFSLKGDNTYQSLPAILDQKQGYKSDVMHGDYKTFWNRDQVYKHFGIDKFYDATYYDMSDKNVVNLGLKDKIFFKDSANYQAKMKSPFYSHLITLTNHYPFTLDEKDATIEKSNTGDATVDGYIQTARYLDEALEEYINDLKKKGLYDNSVIMIYGDHYGISENHNNAMEKLLGEKITPAKFTDLNRTGFWIKIPGKSGGINNEYAGQVDVMPTILHLAGIDTKNYLMFGTDLFSKGHNQVVPFRNGDFITKDYKYVNGKIYSNKNNELITTQPADFEKNKKQVEKDLEMSDNVLNGDLFRFYKNPDFKKVNPSKYKYETGPKANSKK
What is the function of this protein?
Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate, a reaction that presumably uses phosphatidylglycerol (PG) as substrate.  Is required for staphylococcal growth and cell division process (By similarity).
What are the official names of this protein?
Lipoteichoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the LTA synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [Processed glycerol phosphate lipoteichoic acid synthase]: Secreted.
Protein: CBID_GEOSL
Sequence: MSGRELRHGYTTGACAAAAAAGAARMLRRQELADEAEIVLPRGERVAFRLHGQEFTETWATCHVVKDAGDDPDVTNGAEIHATVRREALNRPGARTMVFVTGGRGVGTITKPGLAVPVGEPAINPVPMRMITEAVKAEFSVVCLPQILTVTVSIPNGEELAKKTLNARLGIVGGLSILGTTGIVRPISAKAWTDTLDAAIDVALACGCRTLVLSTGRTSELVVQGALAGEHLREEACVMMGDHVGYALRACARKGAEQAVLAGQFAKLLKIACGHEQTHVSSSELDLRLLAEWIAATPAASHLASLVEGANTARQVLEASGNDPALMELVCSRAREAARLLAPSLRIKVLLAGYDSTVLYFG
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: RBL_SANCA
Sequence: VGFKAGVKDYKLTYYTPDYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEDNQYICYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHAGTVVGKLEGEREITLGFVDLLRDDFVEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIR
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: 3NB_OXYFU
Sequence: QAIGPPFGLCFQCNQKTSSDCFNAKRCPPFHRTCYTLYKPDGGEEWAVKGCAKGCPTAGPDERVKCCHTPRCNN
What is the function of this protein?
Reptile-specific three-finger toxin that is lethal at low doses for lizards, but not for mice.  Probably acts as a neurotoxin.
What are the official names of this protein?
Fulgimotoxin, FTx.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Ancestral subfamily. Boigatoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MTR1L_HUMAN
Sequence: MGPTLAVPTPYGCIGCKLPQPEYPPALIIFMFCAMVITIVVDLIGNSMVILAVTKNKKLRNSGNIFVVSLSVADMLVAIYPYPLMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIFNIVAIAINRYCYICHSLQYERIFSVRNTCIYLVITWIMTVLAVLPNMYIGTIEYDPRTYTCIFNYLNNPVFTVTIVCIHFVLPLLIVGFCYVRIWTKVLAARDPAGQNPDNQLAEVRNFLTMFVIFLLFAVCWCPINVLTVLVAVSPKEMAGKIPNWLYLAAYFIAYFNSCLNAVIYGLLNENFRREYWTIFHAMRHPIIFFSGLISDIREMQEARTLARARAHARDQAREQDRAHACPAVEETPMNVRNVPLPGDAAAGHPDRASGHPKPHSRSSSAYRKSASTHHKSVFSHSKAASGHLKPVSGHSKPASGHPKSATVYPKPASVHFKADSVHFKGDSVHFKPDSVHFKPASSNPKPITGHHVSAGSHSKSAFSAATSHPKPTTGHIKPATSHAEPTTADYPKPATTSHPKPTAADNPELSASHCPEIPAIAHPVSDDSDLPESASSPAAGPTKPAASQLESDTIADLPDPTVVTTSTNDYHDVVVIDVEDDPDEMAV
What is the function of this protein?
Does not bind melatonin.
What are the official names of this protein?
Melatonin-related receptor, G protein-coupled receptor 50, H9.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL18_NOSS1
Sequence: MKLTRRESKERRHRRVRGKVQGSPERPRLAVFRSNEHIYAQVIDDTQHHTLAAASTVEPELKSSLASGSNCEASAQIGKLIAARSLEKGITKVVFDRGGNLYHGRIKALAEAAREAGLDF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: TTGR_PSEPK
Sequence: MVRRTKEEAQETRAQIIEAAERAFYKRGVARTTLADIAELAGVTRGAIYWHFNNKAELVQALLDSLHETHDHLARASESEDELDPLGCMRKLLLQVFNELVLDARTRRINEILHHKCEFTDDMCEIRQQRQSAVLDCHKGITLALANAVRRGQLPGELDVERAAVAMFAYVDGLIGRWLLLPDSVDLLGDVEKWVDTGLDMLRLSPALRK
What is the function of this protein?
Probable regulatory protein for the ttgABC efflux pump operon.  May function as a repressor (By similarity).
What are the official names of this protein?
Probable HTH-type transcriptional regulator TtgR, Efflux pump ttgABC operon regulator.
Protein: TRUB_KORCO
Sequence: MIDEVEEIAVKSAYEPGPYGYRPQERPIFLYLDHGLIILDKPKGPSSHEVTERVKRILEYPGKVGHCGTLDPKVSGVLPIVLGNATKLSKFISGYDKEYVGTLYLHGDVPIDELKGALDKFTGPIFQRPPVKSAVKRSLRVRRVYSIELLSSEGRFHKLRVRVESGTYIRKLFFDIGEFLGVGGSMRDLRRIRSGIFTEKDCVTLEDIKDAYDSWRESGDESKIRKVILPLEEAVRHLPKIYVKDSAVASLTHGASLKVKGICSLSRGIKKGSIVALMTLKGELIAIGRALMDFDEMLSADSGVAASIERVIMPRDLYPPMWKTG
What is the function of this protein?
Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
Probable tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
Protein: CAS1A_ARCFU
Sequence: MRLVVDGFGKYLGIENGLIVVKEKGKALRKVRPEDLKQVLIIGKAAISSDAIKLLLKNRVDVVFLDFNGEILGRLSHPLIGTAKTRREQYLAYGDKRGVHLAKEFIKAKMANQMAILTNLAKARKDSNPEVAESLLKAKKEIDACLNELDGVEAEMIDKVRERLLGIEGKASKHYWDAISLVIPEEYRFNGRRGIEIGSPRYAKDIVNAMLNYGYSILLAECVKAVELAGLDPYAGFLHVDVSGRSSLAIDLMENFRQQVVDRVVLRLISYRQIKPEDCEKRNMVCQLSDNARRLLLASLLERLDSKTQYRGRNLAYSSIILLHARDVVAFLRGERRYEGFVQKW
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Involved in the integration of spacer DNA into the CRISPR cassette (By similarity).  Acts as a dsDNA and ssRNA nuclease, binds to linear and circular dsDNA and linear ssRNA and ssDNA.
What are the official names of this protein?
CRISPR-associated endonuclease Cas1 1.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endonuclease Cas1 family.