PharMolix/UniProtQA huggingface dataset:
Protein: Y1306_STRMU
Sequence: MSEKKIDLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALVPKFLELVESSGENDKVALVVDMRSRLFFKEVSSILDKIDLNETINFRILFLDATDSELVSRYKETRRSHPLATTGRVLDGIALERELLAPLKNLSQNVVDTTDLTPRQLRKTISDQFSVEKSQTSFRLEVVSFGFKYGLPLDADLVFDVRFLPNPYYKPELRDKTGLDKDVSDYVMQHQESEEFYQHLLALLAPILPGYQKEGKSVLTIAIGCTGGQHRSVAFAHRLAQDLGQNWTVNESHRDKNRRKETVNRS
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein SMU_1306c.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: SYFA_HAEIE
Sequence: MQHLNELIEKAKLAIESIQDRSLTALDEIRVEYFGKKGHFTQLMQELRNVSAEERPAMGAKINEAKQAALEFLNAKKTEWEQAELNAKLEKERVDVSLPGRKVETGGLHPVTMTINRVTKFFSELGFSVENGPEIESDYYNFDALNIPKHHPARADHDTFWFNPELLLRTQTSGVQIRTMEKMQPPIRIMAPGRVYRNDYDQTHTPMFHQIELLYVDKKANFTELKGLLHDFLRAFFEEDLQVRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRNVGIDPNEYSGFAVGMGVERLTMLRYNVTDLRSFFENDLRFLKQFK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG4_VANPO
Sequence: MELSQKEIGLDRSKDDNGLSSNDYVVLGIHYPIDSDDDKVVELANKRSNSAGGSIGMFQQFFNKVEEFDYHPGFLSDVISRIHFTYRTKFIPIARSDDGPSPLRINFLIGDNPFNAIENAIYNPNCFNTDIGWGCMIRTGQSLLANAIQIAILGREFRVNDGDVNEQERKIISWFMDTPDEPFSLHNFVKKGCELSSKKPGEWFGPAATSRSIQSLVEQFPDCGIDRCIVSVSSADIFKDEINDIFKNKRYSNILLLMGVKLGVDKVNEYYLKDIRKILESRYSVGISGGRPSSSLYFFGYQDDTLLYFDPHKPQPSTIESLLETCHTDNFDKINISDMDPSMLIGVLLQGEDDWQSWSNEVFDSKIINILNSRNDVTIAEDSMSLEETLEPPDNEYVDLGPMSQQLNGSP
What is the function of this protein?
Cysteine protease that plays a key role in cytoplasm to vacuole transport (Cvt) and autophagy by mediating both proteolytic activation and delipidation of ATG8.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  The protease activity is required for proteolytic activation of ATG8: cleaves the C-terminal amino acid of ATG8 to reveal a C-terminal glycine.  ATG8 ubiquitin-like activity requires the exposure of the glycine at the C-terminus for its conjugation to phosphatidylethanolamine (PE) and its insertion to membranes, which is necessary for autophagy.  The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy.  In addition to the protease activity, also catalyzes deconjugation of PE-conjugated forms of ATG8 during macroautophagy: ATG8 delipidation is required to release the protein from membranes, which facilitates multiple events during macroautophagy, and especially for efficient autophagosome biogenesis, the assembly of ATG9-containing tubulovesicular clusters into phagophores/autophagosomes, and for the disassembly of PAS-associated ATG components.  ATG8 delipidation by ATG4 also recycles ATG8-PE generated on inappropriate membranes to maintain a reservoir of unlipidated ATG8 that is required for autophagosome formation at the PAS.
What are the official names of this protein?
Probable cysteine protease ATG4, Autophagy-related protein 4.
What is the protein family that this protein belongs to?
Belongs to the peptidase C54 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Preautophagosomal structure.
Protein: MNMG_RICPU
Sequence: MLKYDVIVIGGGHAGVEAAAASARLGVPTLLITLKPENLGEMSCNPAIGGIAKGTLVKEIDALDGLMGYVIDQAGIHYKMLNETRGPAVWGPRAQADRKLYKKAMYQILTNYPNLDILYGKVEDIEIKSSKIEAVILNNGSKILCQKIILTTGTFLSGLIHIGQKKIPAGRVDEEPSYGLSNTLKQIGFKLARLKTGTPPRIDGRTIDYSKTILQPGDKIPRPFSELTNIVNVSQINCFITTTTSETHDIIRENLDKSAMYSGQIEGIGPRYCPSIEDKIVRFSTKSEHRIFLEPEGLDDYTIYPNGISTSLPEDVQHKLIKTIPGLENVKVLRPGYAIEYDYVDPREISVTLETKKIAGLYLAGQINGTTGYEEAAGQGIIAGINAALAVKDQAPFMLTRANSYIGVMIDDLTTFGTIEPYRMFTSRSEYRLSLRADNSDLRLTELGMNIGVVSEKRKKIFTKKCEDIEKIKSLLNTLSLTTSKLAKMGIQVAQDGTYKTVLDLFKIPNFNVEQAIKIFPMLKETQNNNILQLLYIEAKYASYLTRQHADINLFQSEEAQFIPKNLDYFKIPSISLEIQEKLSSHKPTTIGVARRIPGITPAAITAIIIYLKTKYSDGSST
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPE_BARHE
Sequence: MPVLTDPLQILQALIRCPSVTPHEAGALSTLEQFLTKMGFHVERPIFADKNTEDVENLYAKMGKEGPHLMFAGHTDVVPPGDLENWKYPPFEGVIDQGKLYGRGAVDMKGGIACFVAAFARVLEKRTIKGRVSLLITGDEEGPALNGTVKLLKWAEQKGEKWTAALVGEPTSVKTVGDVIKIGRRGSISGIMTVKGRQGHVAFPERAANPLPLASKLIQSLIQTTLDEGTENFQPSNLELTAIDTGNPAMNVIPAQATVHFNIRYNDLWTKEMLMAEIENRLALVQSKNNNGQYPYYQLEWIPSLGDVFLTKNDKLINTLSNAIKSVTGNIPECSTSGGTSDARFIKDYCPVIEFGLPGQTMHMVDECVTVDAMETLTSIYECFIVDFFA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: ACTT1_MACFA
Sequence: MFNPHVLDVPAVIFDNGSGLCKAGVSGEIGPRHVINSVLGHRKFNMPSARLNQYFVGQEALYKFDALHLHYPIKRGLVTGWDDMEKLWKHLFEWELGVKPSQQPVLMTEPSLNPREIREKLAEMMFENFSVPGFYLSNHAVAALYASACVTGLVVDSGDGVTCAVPIFEGYSLPHAVTKLYTAGRDITEHLTQLLFANGFNFPCILNKAVANNIKEKLCYIALEPEKELRKSRGEVLGAYRLPDGHVIHFGDELYQVPEVLFAPDQLGIHSPGLSKMVSSSIMKCDTDIQNKLYAEIVLSGGTTLFPGLEERLMKEVEQLASKGTPIKITASPDRCFSAWIGASIMTSMSSFKQMWVTSADFKEYGTSVVQRRCF
What is the function of this protein?
Negatively regulates the Hedgehog (SHH) signaling.  Binds to the promoter of the SHH signaling mediator, GLI1, and inhibits its expression.
What are the official names of this protein?
Actin-related protein T1.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm. Nucleus. Note=Both detected in the nucleus and cytoplasm, localizes to the nucleus where it binds chromatin upon stimulation of the Hedgehog pathway.
Protein: DTBP1_BOVIN
Sequence: MLETLRERLLSVQQDFTSGLKTLSDKSREAKAKNKPRTVPCLPKYSAGLELLSRYEDTWAALHRRAKECASAGERVDSEVVMLSAHWEKKQASLRDLQQQLQQLPGLIADLESLTASLTHLEASFEEVENHLLNLEDLCGQCELERHKHMQSQQLENYKKNKRKELETFKAELDAEHSQKVLEMEQTQQLKLKERQKFFEEAFQQDMEQYLSTGYLQIAERREPMGSMSSMEVNVDMLEQMDLMDISDQEALDVFLNSGGEENTLLSPISGPEASPGQDAVTLQVPTPSQAPATPPSSSSPGTDPASRDPSEGGESPVVQSDEEGVEVDTALATLHSDDSDS
What is the function of this protein?
Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes.  In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.  The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension.  Associates with the BLOC-2 complex to facilitate the transport of TYRP1 independent of AP-3 function.  Plays a role in synaptic vesicle trafficking and in neurotransmitter release.  Plays a role in the regulation of cell surface exposure of DRD2.  May play a role in actin cytoskeleton reorganization and neurite outgrowth.  May modulate MAPK8 phosphorylation.  Appears to promote neuronal transmission and viability through regulating the expression of SNAP25 and SYN1, modulating PI3-kinase-Akt signaling and influencing glutamatergic release.  Regulates the expression of SYN1 through binding to its promoter.  Modulates prefrontal cortical activity via the dopamine/D2 pathway (By similarity).
What are the official names of this protein?
Dysbindin, Biogenesis of lysosome-related organelles complex 1 subunit 8, BLOC-1 subunit 8, Dysbindin-1, Dystrobrevin-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the dysbindin family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Melanosome membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus. Postsynaptic density. Presynaptic cell membrane. Endoplasmic reticulum. Note=Mainly cytoplasmic but shuttles between the cytoplasm and nucleus. Exported out of the nucleus via its NES in a XPO1-dependent manner. Nuclear localization is required for regulation of the expression of genes such as SYN1 (By similarity). Detected in neuron cell bodies, axons and dendrites. Detected at synapses, at postsynaptic density, at presynaptic vesicle membranes and microtubules. Detected at tubulovesicular elements in the vicinity of the Golgi apparatus and of melanosomes. Occasionally detected at the membrane of pigmented melanosomes in cultured melanoma cells. The BLOC-1 complex associates with the BLOC-2 complex in early endosome-associated tubules. Associated with the AP-3 complex at presynaptic terminals (By similarity).
Protein: NCBP1_ANOGA
Sequence: MNRRRAYEDDGDFYGERNKKRRRVSENQEMEERLETLILRVGENSTSSLESNLEGLVSVLESDLGNFRSKILRILSDCPIKMPEKCTIYSTMVGLMNAKNYNFGGEFVEYMVKTFKDSLKQCQWDAARYALRFLADLVNCHVISTNSLLQLLDSMVDAANEDNVPQVRRDWYVFAVLSTLPWVGRELYEKKESALENLLVRIEVFLNKRTKKHHNALRVWSVDAPHPQEEYLDCLWAQIRKLRQDNWTEKHIPRPYLAFDSVLCEALQHNIPVIHPPPHQDSFEYPMPWVVYRMFDYTDCPPGPILPGAHSIERFLIEEHLHSIIEMHRWERKDCAIHLLMLPYKDKIPLEYCIVEVIFAELFHMPTPRYLEICYGSILIELCKQQPSKMPQVLAQATEILFMRIDSMNTSCFDRFVNWFSYHLSNFQFRWSWDDWDSCLLLENEHPRPKFIQEVLLKCLRFSYHDRFKEMMPEGYAKLIPKPPVPHYKYSMEGAASLPGTATAHKLVVAIRQKCNAEDVLNELNDLPNSRDASDTDMAEAPFNPLKIDVFVQTLLNLGSKSFSHSFAAISKFHAVFKALAETEEAQICILHNMFELWVDHQQMMVVIVDKLLKVQIVECSAVATWVFSKEMVGEFTKMYLWEILHLTIKKMNQHVTKLSREMNEAKEKLARTVESSSSESEDEAASPNAQKRRKNTEGSGEKPTEEQVERMEEKLEAAYVDQKRLFLIIFQRFIMILSEHLVKCDTDGRDYDTDWYRWTIGRLQQVFMMHHEQVQKYSSTLESLLFTSDLDPHILDVFHQFTALRA
What is the function of this protein?
Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi).  The CBC complex is involved in miRNA-mediated RNA interference and is required for primary microRNAs (miRNAs) processing.  Also involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production.  In the CBC complex, Cbp80 does not bind directly capped RNAs (m7GpppG-capped RNA) but is required to stabilize the movement of the N-terminal loop of Cbp20 and lock the CBC into a high affinity cap-binding state with the cap structure (By similarity).
What are the official names of this protein?
Nuclear cap-binding protein subunit 1, 80 kDa nuclear cap-binding protein, CBP80, NCBP 80 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the NCBP1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SHCBP_HUMAN
Sequence: MADGSLTGGGLEAAAMAPERMGWAVEQELASLEKGLFQDEDSCSDCSYRDKPGSSLQSFMPEGKTFFPEIFQTNQLLFYERFRAYQDYILADCKASEVQEFTAEFLEKVLEPSGWRAVWHTNVFKVLVEITDVDFAALKAVVRLAEPYLCDSQVSTFTMECMKELLDLKEHRLPLQELWVVFDDSGVFDQTALAIEHVRFFYQNIWRSWDEEEEDEYDYFVRCVEPRLRLHYDILEDRVPSGLIVDYHNLLSQCEESYRKFLNLRSSLSNCNSDSEQENISMVEGLKLYSEMEQLKQKLKLIENPLLRYVFGYQKNSNIQAKGVRSSGQKITHVVSSTMMAGLLRSLLTDRLCQEPGEEEREIQFHSDPLSAINACFEGDTVIVCPGHYVVHGTFSIADSIELEGYGLPDDIVIEKRGKGDTFVDCTGADIKISGIKFVQHDAVEGILIVHRGKTTLENCVLQCETTGVTVRTSAEFLMKNSDLYGAKGAGIEIYPGSQCTLSDNGIHHCKEGILIKDFLDEHYDIPKISMVNNIIHNNEGYGVVLVKPTIFSDLQENAEDGTEENKALKIQTSGEPDVAERVDLEELIECATGKMELCARTDPSEQVEGNCEIVNELIAASTQKGQIKKKRLSELGITQADDNLMSQEMFVGIVGNQFKWNGKGSFGTFLF
What is the function of this protein?
May play a role in signaling pathways governing cellular proliferation, cell growth and differentiation.  May be a component of a novel signaling pathway downstream of Shc.  Acts as a positive regulator of FGF signaling in neural progenitor cells.
What are the official names of this protein?
SHC SH2 domain-binding protein 1.
What are the subcellular locations of this protein?
Midbody. Cytoplasm, cytoskeleton, spindle. Note=Displays weak localization to the spindle midzone in some early telophase cells and is concentrated at the midbody in late cytokinesis.
Protein: RL6_VIBC3
Sequence: MSRVAKAPVAIPAGVEVKLNGQEITIKGAKGELSRVFHKGVVIAQEDNQLTFGPREGVANAWAQAGTARALVKNMVVGVTEGFTKKLVLKGVGYRAAMKGNAVGLTLGFSHPVEHELPEGIKAECPSQTEIVLTGCDKQLVGQVAADIRSYRAPEPYKGKGIRYADENVRSKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: DLD_ECOLI
Sequence: MSSMTTTDNKAFLNELARLVGSSHLLTDPAKTARYRKGFRSGQGDALAVVFPGSLLELWRVLKACVTADKIILMQAANTGLTEGSTPNGNDYDRDVVIISTLRLDKLHVLGKGEQVLAYPGTTLYSLEKALKPLGREPHSVIGSSCIGASVIGGICNNSGGSLVQRGPAYTEMSLFARINEDGKLTLVNHLGIDLGETPEQILSKLDDDRIKDDDVRHDGRHAHDYDYVHRVRDIEADTPARYNADPDRLFESSGCAGKLAVFAVRLDTFEAEKNQQVFYIGTNQPEVLTEIRRHILANFENLPVAGEYMHRDIYDIAEKYGKDTFLMIDKLGTDKMPFFFNLKGRTDAMLEKVKFFRPHFTDRAMQKFGHLFPSHLPPRMKNWRDKYEHHLLLKMAGDGVGEAKSWLVDYFKQAEGDFFVCTPEEGSKAFLHRFAAAGAAIRYQAVHSDEVEDILALDIALRRNDTEWYEHLPPEIDSQLVHKLYYGHFMCYVFHQDYIVKKGVDVHALKEQMLELLQQRGAQYPAEHNVGHLYKAPETLQKFYRENDPTNSMNPGIGKTSKRKNWQEVE
What is the function of this protein?
Catalyzes the oxidation of D-lactate to pyruvate.  Electrons derived from D-lactate oxidation are transferred to the ubiquinone/cytochrome electron transfer chain, where they may be used to provide energy for the active transport of a variety of amino acids and sugars across the membrane.
What are the official names of this protein?
Quinone-dependent D-lactate dehydrogenase, (R)-lactate:quinone 2-oxidoreductase, D-lactate dehydrogenase, D-LDH, Respiratory D-lactate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the quinone-dependent D-lactate dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=May bind the membrane through electrostatic rather than hydrophobic forces.
Protein: Y4780_ALKMQ
Sequence: MAKKGFPGMGGAPNMNNMMKQVQKMQKDMEKTQAALEEKEVEASAGGGAITVKVSGKKEVISIEIKPEVVDPEDVEMLQDLIMAAVNEAMRGAEEMVSKEMGKVTGGMNIPGLF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Amet_4780.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: CDPAS_PYRAB
Sequence: MNPIFEAFWYILPAYFANSSPVVLGGGTPIDFGKKWRDGRRIFGDGKTWRGFFGGITVGTVVGTIQHLMFPGYYGSLKLAVGVAFLLSLGALVGDLIGSFIKRRLNMPRGYPAVGLDQWGFLISALCFAYPLRTIPTGEVLFLLVVTPVIHWLANVFAYRMKWKNVPW
What is the function of this protein?
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP.  This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
CDP-archaeol synthase, CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-archaeol synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: THIQ_SHIFL
Sequence: MLKLTDITWLYHHLPMRFSLTVERGEQVAILGPSGAGKSTLLNLIAGFLTPASGSLTIDGVDHTTTPPSRRPVSMLFQENNLFSHLTVAQNIGLGLNPGLKLNAAQQEKMHAIARQMGIDNLMARLPGELSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQEMLTLVSTSCQQQKMTLLMVSHSVEDAARIATRSVVVADGRIAWQGKTEEVLSGKGSASAIWGIQG
What is the function of this protein?
Part of the ABC transporter complex ThiBPQ involved in thiamine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Thiamine import ATP-binding protein ThiQ.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y2491_LISIN
Sequence: MNPIVEFCVNNLASGADAAFAKLDADDSLDVIEYDCLTYCDLCATSLFALVDGEVVRGETAEELVANIYTFLEENPF
What are the official names of this protein?
UPF0349 protein lin2491.
What is the protein family that this protein belongs to?
Belongs to the UPF0349 family.
Protein: ATPG_NITEC
Sequence: MASSREIRNKIKSIKNTQKITRAMEMVAASKMRKAQDRMKKARPYGEKIRNVAAHMSKASVEYRHPFLIDRNSVKRVGIIVVTSDKGLCGGLNTNVLRRALNEIRVWGAEGEQIEVCCIGNKGLGFMSRLGVRVISQVTGLGDAPNMEKLIGAVKVVLDAYTDDHFDRVYIFYNRFVNTMKQIPVMEQLLPLTDEHMRDDGNEAKPARAPWDYIYEPEAKPVIDDIMIRYIEALVYQAVAENMASEQSARMVAMKAASDNAGNLIDELTLIYNKSRQAAITKELSEIVGGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y1317_HAEIN
Sequence: MKTTLLKTLTPELHLVQHNDIPVPSLKTCGWNTKNFPCKGHSLSVGXPQNAKQDVLWLSEVEPFKNGNAIRGGVPICYPWFGGVKQPAHGTARIRLWQLSHYYISVHKVRLEFELFSDLNIIEAKVSMVFTDKCHLTFTHYGEESAQAALHTYFNIGDINQVEVQGLPETCFNSLNQQQENVPSPRHISENVDCIYSAENMQNQILDKSFNRTIALHHHNASQFVLWNPWHKKTSGMSETGYQKMLCLETARIHHLLEFGESLSVEISLKG
What are the official names of this protein?
Putative glucose-6-phosphate 1-epimerase, Putative D-hexose-6-phosphate mutarotase.
What is the protein family that this protein belongs to?
Belongs to the glucose-6-phosphate 1-epimerase family.
Protein: CAPSD_CMVI1
Sequence: MDKSESTSAGRNRRRRPRRGSRSAPSSADANFRVLSQQLSRLNKTLAAGRPTINHPTFVGSERCRPGYTFTSITLKPPKIDRGSYYGKRLLLPDSVTEYDKKLVSRIQIRVNPLPKFDSTVWVTVRKVPASSDLSVAAISAMFADGASPVLVYQYAASGVQANNKLLYDLSAMRADIGDMRKYAVLVYSKDDALETDELVLHVDIEHQRIPTSGVLPV
What is the function of this protein?
Capsid protein.  Probably binds RNA and plays a role in packaging (By similarity).
What are the official names of this protein?
Capsid protein, CP, Coat protein.
What is the protein family that this protein belongs to?
Belongs to the cucumovirus capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: CFC1_MOUSE
Sequence: MRANSPTQGISLKMHQARPLFLVTVALQLIGLGYSYQSEGDGAREVSNILSPVIPGTTLDRTLSNSSRKNDIPEGARLWDSLPDSSTLGESAVPVSRCCHNGGTCVLGSFCVCPAYFTGRYCEHDQRRRDCGALGHGAWTLHSCRLCRCIFSALYCLPHQTFSHCDLKSFLSSGARGSRECSIPSLLLLVLCLLLQGVAGKG
What is the function of this protein?
Nodal coreceptor involved in the correct establishment of the left-right axis.  May play a role in mesoderm and/or neural patterning during gastrulation.
What are the official names of this protein?
Cryptic protein.
What is the protein family that this protein belongs to?
Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor. Secreted.
Protein: BOSS_DROVI
Sequence: MSGLQLIWKSPTQLVLFVLLITISCIDLCHAVGAATPTKKSPPVRITKPQPVSSTTTAIPTTNEGSTTGEQLALLVSSTTEGTASSASSSSNGGSDDSSSTTAAGSLVPEICITGLQLSFTNADGEQVVRKQQELVQVIEGDVMLSVITSDPVSALFVINRVNQANLISADFEVGIRAINVDNASLAENLLIQEVQYLQQCTQYSMGIFIDFDLYKRLESIIRDLEYNVWPIPSARAHLFPKVAHLLHQMPWGEKIASVEIVTETLDIYNEFMDAARQEHMCLMHFKSDDNVYILFGNKMANHFKENGTVFAVPTERTEHIFLEELPNKSFILMENGIELRTADLDPMPTTLDEVLIGKSVLPSRILVFASPIVDLMNWLRGSLAKHCKRDEDLYMLESCFNFLNFIEDWRTPEYRRTHDTAELLSLLRMRKLSTSMLFQMYQKKQETVDVITGESRMELREIASQNFVTNVTTYYHYNRDNHTSLELKTKFGLVFNCQFTAGENRRYPFLFDGESVMFWRIKLDTWVATGLTAAILGLIATLAILVFIVVRISLGDVFEGNPVTSILLLLSLILVFCSFVPFSMEYVGEQRNSHVTFEDVHTLNTLCGVRVFIMTLVYCFVFSLLLCRAVMLASIGSEGGFLSHVNGYIQAIICVLSVFVQVGMSVQLLVVMHLASESVSCENIYYGRWLWGLLAYDFLLLCSLVSLVPFIYRSQRNYREGILIVIGAVLILIIWSVWIALSMFGDEWRDAAIPLGMQASGWAVLVGILIPRTFLIVRGIERSDIAQALPSLTSLAFAQNNQYSSEQSVYECVNPAMRHCSQEEMNHQSPSEIPTLPLRGGGPRRQQFFANLRQANANINPQRPPPHPQQSPSRSSVCSLPPSPDHSKITRF
What is the function of this protein?
Acts as a ligand for sevenless tyrosine-kinase receptor during eye development.
What are the official names of this protein?
Protein bride of sevenless.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATAT_LEIMA
Sequence: MRRRPPQLTKTKLADEEVPELTLVPDGVSRWTGSDLDALLNAARRGGAEAAQQDLERKLCRTIDILGARSQQAQEINAVLTSVARLRENSTFRLYLLTQNHRGVGILKVGVKKLFVTHPVTCGLVEVDPLCVLDFYVDESCQRQGYGKMLYSHMLKAEHVSRPEVLAIDRPSNKLLGFLRKHYGLAAYTPQVNNFVVFHSFFDHTTVSERGKLLRAPSPARASPFPSSANATVAIGGAKAKNWTPG
What is the function of this protein?
Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules.  Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity.  Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer.  Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules.  Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released.
What are the official names of this protein?
Alpha-tubulin N-acetyltransferase, Alpha-TAT, TAT, Acetyltransferase mec-17 homolog.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase ATAT1 family.
Protein: NADE_SALAR
Sequence: MTLQQEIIQALGAKSYINPEEEIRRSVDFLKAYLKTYPFLKSLVLGISGGQDSTLAGKLSQMAISELREETDDDALQFIAVRLPYGVQADEQDCQDAIAFIKPDRVLTVNIKGAVLASEQALREAGIELSDFVRGNEKARERMKAQYSIAGMTHGVVVGTDHAAEAITGFFTKYGDGGTDINPLHRLNKRQGKQLLAALGCPEHLYKKVPTADLEDDRPSLPDEAALGVTYDNIDDYLEGKTLAPAIAKIIEGWYVKTEHKRRLPITVFDDFWKK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: Y1593_PYRAB
Sequence: MKAEIITVGDELLTGNTVDSNSAFIASKLTEKGYLVRRITTVGDDVEEIKSIILEALDRKPDVLVISGGLGPTHDDVTMLAVSKALNRELELCEECLERIRKFYVELHKKGLIDDPELNEARKKMAYLPKGATPLQNTEGAAPGAFIEHEGIKIFVLPGMPREMKAMLLNEVLPRLGERTFIQKKYLAEITDESKLAPILSEAIRKFNVRIHSSPKGFGKYIGIIIFGEDEEIIEKVIEFMQSRGISFKEGW
What are the official names of this protein?
Protein PYRAB15930.
What is the protein family that this protein belongs to?
Belongs to the CinA family.