PharMolix/UniProtQA huggingface dataset:
Protein: EI3D1_DROYA
Sequence: MSETINTAAQFPSFEKPTVQFNEKGWGPCELPDTFKDVPYQPFSKNDRLGKICDWTNTSNNDKKYQNKYASSFGTGNQYSYYHEEDETTFHLVDTARVQKPPHQRGRFRNMRNSRSGRGRNARGGLNTHGMTTLSGKNVKARDPRHGRGMGKKFGHRGPPPKMRESSVAVRADWASIEEMDFPRLIKLSLPNIKEGVDIVTCGTLEYYDKTYDRINVKNEKPLQKIDRIVHTVTTTDDPVIRRLSKTVGNVFATDAILATIMCSTRSNYSWDIVIEKVGDKIFMDKRDHTEFDLLTVNESSVEPPTDDDSSCNSPRNLAIEATFINHNFSQQVLKTGDQEPKYKFEESNPFISEDEDIQVASVGYRYKKWELGSDIVLVARCEHDGVLQTPSGDSQFMTIKALNEWDSKLANGVEWRQKLDTQRGAVLANELRNNACKLAKWTVQAVLAGSDQLKLGYVSRINPRDHSRHVILGTQQFKPHEFATQINLSMDNAWGILRCIIDLVMKQKDGKYLIMKDPNKPIIRLYDIPDNTFDSDDSDDGEGDDEGFQQVYNYAHNKI
What is the function of this protein?
mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.  In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit D-1, eIF3d-1, Eukaryotic translation initiation factor 3 subunit 7-1, Eukaryotic translation initiation factor 3 subunit p66.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit D family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1819_SYNY3
Sequence: MEAKELVQRYRNGETLFTGLKLPGINLEAADLIGIVLNEADLRGANLLFCYLNRANLGQANLVAANLSGASLNQADLAGADLRSANFHGAMLQGAILRDSDMTLATLQDTNLIGADLRGADLSGATLTGACLRGANMRQEKKGYYTNLQAAILGRADLQGANMKGVDLSRADLSYANLKEANLRDVDLRKADLSYANLKGALLTDANLSGAKLNGADLQNANLMRAKISEAEMTAVNCQGAIMTHVNLNRTNLTGSNLSFTRMNSADLSRANLTKANLQEAELIEAFFARANLTEANFINANLVRADLMSANMVGADFQGATMPDGQVRHH
What are the official names of this protein?
Uncharacterized protein slr1819.
Protein: VP26B_ARATH
Sequence: MNYLLGAFKPACNISITFSDGKNRKQVPMKKENGQTALVPLFHSQDTISGKVCIEPYQGKKVEHNGVKVELLGQIEMYFDRGNFYDFTSLVRELDVPGEIYERKTYPFEFPTVEMPYETYNGVNVRLRYVLKVTVTRGYAGSILEYQELVVRNYAPLPDINNSIKMEVGIEDCLHIEFEYNKSKYHLKDVILGKIYFLLVRIKMKNMDLEIRRRESTGAGANTHVETETLAKFELMDGTPVRGESIPVRLFLAPYDLTPTHRNINNKFSVKYYLNLVLVDEEDRRYFKQQEITLYRLKEDASS
What is the function of this protein?
Plays a role in vesicular protein sorting.  Component of the membrane-associated retromer complex which is essential in endosome-to-Golgi retrograde transport.  The VPS29-VPS26-VPS35 subcomplex may be involved in recycling of specific cargos from endosome to the plasma membrane.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 26B, Vesicle protein sorting 26B.
What is the protein family that this protein belongs to?
Belongs to the VPS26 family.
What are the subcellular locations of this protein?
Cytoplasm. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Prevacuolar compartment membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PG128_VACCW
Sequence: MSWYEKYNIVLNPPKRCSFACADNLTTILAEDGNNIRAILYSQPKKLKILQDFLATSRNKMFLYKILDDEIRRVLT
What is the function of this protein?
Late protein which probably participates in disulfide bond formation by functioning as a thiol-disulfide transfer protein between membrane-associated OPG072 and OPG08.  The complete pathway for formation of disulfide bonds in intracellular virion membrane proteins sequentially involves oxidation of OPG072, OPG128 and OPG08.
What are the official names of this protein?
Protein OPG128.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG128 family.
Protein: MIAB_RHILO
Sequence: MRATAAKKVFIKTYGCQMNVYDSQRMGDALAADGYTATDAIDEADLVLLNTCHIREKAAEKVYSELGRIRDMKAERAIAGRELLIGVAGCVAQAEGAEIIRRSPAVDLVIGPQTYHRLPDVLARVRGGEKIVETDYAIEDKFDHLPQPKRAEVIKRGVTAFLTVQEGCDKFCTFCVVPYTRGSEVSRPVAQIVAEAERLAEAGVREVTLLGQNVNAWHGQGENGEEWGLGRLLFRLAEIPGLARLRYTTSHPRDMDDELISAHRDLPSLMPYLHLPVQSGSDRILKAMNRRHTARDYLALLDRIRAARPDIALSGDFIVGFPGETEADFEATMELVRQVNYASAFSFKYSPRPGTPGAEMPDHVPETLKDERLQRLQALLLKQQQGFGSSLVGSTIDTLIEKPGRQAGQKVGRTPWLQPVIVDEKAGEIGDIIQVRITKTGYNSLFAELA
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF17_CYACA
Sequence: MPKYGFHQSTELINGRLAMLAFILSLFIEFITEQKILHFLKFL
What is the function of this protein?
Possible role in chlorophyll and/or carotenoid binding.
What are the official names of this protein?
Uncharacterized protein ycf17, ORF48.
What is the protein family that this protein belongs to?
Belongs to the ELIP/psbS family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS16_PARP8
Sequence: MVIIRLARGGSKKRPFYNIVATDSRSRRDGRFIERVGFYNPVATKGESLRIAQDRLTYWQGVGAQLSPTVQRLVKEAQKAQPAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: LPXC_SALPC
Sequence: MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDLNPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIPIMDGSAAPFVYLLLDAGIDELNCAKKFVRIKETVRVEDGDKWAEFRPYNGFTLDFTIDFNHPAIDSSSQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVVDDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVLAKQEAWEFVTFQDDAELPLAFKAPSTVLA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: RLME_BURMS
Sequence: MAKNRFNQSWLHDHINDPYVKMAQREGYRARAAYKLKEIDEQDKLIRPGQVIVDLGAAPGSWSQYARNKLAQGKRRDAVREGGIDGTIIALDMLPMEPVADVHFIQGDFREESVLHQLEEVLAGRAVDLVISDMAPNLSGVAVADAARIEHVCDLALEFAQNHLKPDGALLVKCFHGSGYSQIVEKFKHQFKTVAPRKPKASRDKSSETFILGRHLKQPR
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGC_CORJK
Sequence: MKSRSNVLSIVLAGGEGKRLYPFTADRAKPAVPFGGNYRLIDFVLSNLVNAGYYKICVLTQYKSHSLDRHISQSWQLSGLTGQYITPVPAQQRLGKRWFTGSADAILQSLNLVYDEQPDYIIVFGADHVYRMDPEQMVQEHIKAGAGVTVAGLRVPRHEATAFGVIQADDDNKIEQFLEKPAEPPSVPDDPEVSFASMGNYVFTAQTLIDALKEDSEDENSNHDMGGDIIPRLVDRGEAYVYDFSNNYVPGETERDKGYWRDVGTVDAFYEAHMDLISVHPVFNLYNQQWPIHTAETGNLPPAKFVKGGIAQSSMVSAGCIISAGTVRNSVLSENVVVEEGASVEGCVIMPGVRIGRGAVVRHAIIDKNVQVSAGEIIGVDRARDQDRFTISKGGVVCIGKNVVV
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: ARGA_AERS4
Sequence: MREREPSLVYAFRQSTPYVNVHRGATFVLMMGGEAICHPNFANIVSDIALLQTLGIRLVLVFGSRPQNDEALARAGIEAQYHRRIRVTDDESFAIIKQVCGGLQYDITAQLSMGLANTPMQEARISVVSGNFVTAQPLGVDDGIDFCHSGRVRRIDVEGITRQLDQKGLVLISPIGCSVTGESFNLSSEEVARRVAVDLKADKLICFSSTQGVMDRHGEAISELFPEQAEELLVELEQAGEEMSGTARYLRAAIASCRGGVPRSHLVSYQDDGAMLQELFSRDGLGTQIVRESAEQARAATIEDIGGILDLIRPLEEDGILVRRSREQLEMEIDKFTIIERDGLIIGCAALYCFMEEAMAEMACVAIHPEYRNSNRGDQLVAKVAERAKRLGIRRLFVLTTRSIHWFRERGFDPLEVEDLPVERQRLYNWQRRSKVLSKTIS
What are the official names of this protein?
Amino-acid acetyltransferase, N-acetylglutamate synthase, AGS, NAGS.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. ArgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P13_BPPM2
Sequence: MNRDIYTQIETVGVLEKRVEKAGTFELKAAAMALAKAQRKLSVLLAKGMAELEDRLKIAELRTK
What is the function of this protein?
Transcription factor that regulates expression of phage structural components with protein P14.
What are the official names of this protein?
Transcription factor P13, Protein XIII.
Protein: FOXG1_MNELE
Sequence: MVVTTATKPHPFSIENILKSASPKPQKPLFSYNALIAMAISQSPLKKLTLSEIYDFIIETFPYYRDNKKGWQNSIRHNLSLNKCFVKVPRHYNDPGKGNYWMLNPNSDEVFIGGKLRRRPGQNGGSLESYMHLKTRTSPYQRGDTVCKRDRVVYLSNSGAGNCQFYQPVPCSSPTAMLSRSSLIVQTSPTTLTIPHHPPQNYIQTLSPNVSPVRVGNQTSPRQSALPSSSLPLLPSPPSLPSKLSSPPLPSLSTNLPSPPLDTGDILLSPFLRQTVDSTSQNFLEHMIRIREQVQRSGHLALAQSRAVVYQPIPRKSL
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
Forkhead box protein G1, Brain factor 1, ctenoBF-1.
What are the subcellular locations of this protein?
Nucleus.
Protein: SAND_CORAD
Sequence: MKPAIPPTINLHTIRACNYGCKYCFAGFQDCDTGVMPQADLHEILRQFAATTGMAIHPAKVNFAGGEPMLSPTFVEDICYAKSLGLTTSLVTNGSLLSERLLDKLSGQLDLLTISIDSLKPGTNRAIGRTNRQNPLTVSEYLDRILKARTRGITVKLNTVVNRLNLDEDMTDFIREAQPIRWKLFKVLKIQNENSAHFDSWAIRDEEFVHFVERHRKVESSGVTLVPESNEQMYGTYGIISPDGRFIDNSQGTHRYSPRIVDVGITQAFADVNFSMAGFQQRGGIYSIKRSTTNRSLQTSALHPKRELTK
What is the function of this protein?
Expression of pVip15 in E. coli (strain MG1655) confers resistance to phage T7; prevents culture collapse upon infection.  Catalyzes the conversion of guanosine triphosphate (GTP) to 3'-deoxy-3',4'-didehydro-GTP (ddhGTP), probably via a SAM-dependent radical mechanism (PubMed:32937646).  The modified nucleotide represses transcription from T7 RNA polymerase-directed genes (possibly by acting as chain terminators), strongly suggesting these nucleotides block viral polymerase transcription (By similarity).
What are the official names of this protein?
S-adenosylmethionine-dependent nucleotide dehydratase, SAND, Prokaryotic viperin protein pVip15, pVip15.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Viperin family.
Protein: TOP3_STAA3
Sequence: MKSLILAEKPSVARDIADALQINQKRNGYFENNQYIVTWALGHLVTNATPEQYDKNLKEWRLEDLPIIPKYMKTVVIGKTSKQFKTVKALILDNKVKDIIIATDAGREGELVARLILDKVGNKKPIRRLWISSVTKKAIQQGFKNLKDGRQYNDLYYAALARSEADWIVGINATRALTTKYDAQLSLGRVQTPTIQLVNTRQQEINQFKPQQYFTLSLTVKGFDFQLESNQRYTNKETLEQMVNNLKNVDGKIKSVATKHKKSYPQSLYNLTDLQQDMYRRYKIGPKETLNTLQSLYERHKVVTYPRTDSNYLTTDMVDTMKERIQATMATTYKDQARPLMSKTFSSKMSIFNNQKVSDHHAIIPTEVRPVMSDLSNRELKLYDMIVERFLEALMPPHEYDAITVTLEVAGHTFVLKENVTTVLGFKSIRQGESITEMQQPFSEGDEVKISKTNIREHETTPPEYFNEGSLLKAMENPQNFIQLKDKKYAQTLKQTGGIGTVATRADIIDKLFNMNAIESRDGKIKVTSKGKQILELAPEELTSPLLTAQWEEKLLLIERGKYQAKTFINEMKDFTKDVVNGIKNSDRKYKHDNLTTTECPTCGKFMIKVKTKNGQMLVCQDPSCKTKKNVQRKTNARCPNCKKKLTLFGKGKEAVYRCVCGHSETQAHMDQRMKSKSSGKVSRKEMKKYMNKNEGLDNNPFKDALKNLNL
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.  The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils.  Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.
What are the official names of this protein?
DNA topoisomerase 3, DNA topoisomerase III.
What is the protein family that this protein belongs to?
Belongs to the type IA topoisomerase family.
Protein: ATPA_ANTAG
Sequence: MVNIRPDEISNIIRKQIEQYNQEVKVINIGTVLQVGDGIARIYGLDKVMAGELVEFEDGTVGIALNLESDNVGVVLMGDGLSIQEGSSVEATGKIAQIPVSDAYLGRVVNALAQPIDGKGQIPAYEFRLIESPAPGIISRRSVYEPMQTGLIAIDSMIPIGRGQRELIIGDRQTGKTAVATDTILNQKGQNVICVYVAIGQKASSVAQVVNTFEERGALEYTIVVAETADSPATLQYLAPYTGAALAEYFMYRKQHTLIIYDDLSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSSQLGEGSMTALPIVETQAGDVSAYIPTNVISITDGQIFLSADLFNAGIRPAINVGISVSRVGSAAQIKAMKQVAGKLKLELAQFAELEAFAQFASDLDKATQNQLARGQRLRELLKQSQSAPLAVEEQVATIYTGVNGYLDVLEVEQVKKFLVQLREYLITNKPQFVEIIRSTKVFTEQAEIILKEAIKEHTEFFLLQEQK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, chloroplastic, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: AROC_BRUA1
Sequence: MSHNSFGHLFRVTTWGESHGLALGCVVDGCPPGITFTEAEIQSFLDKRKPGQSKYTTQRREPDQVRVLSGVLLGEDGVTMTTTGTPISMMIENTDQRSKDYGEIARQYRPGHADYAYDVKYGIRDYRGGGRSSARETAARVAAGAIARKVVPGLEVRGALVSIGAHDIDRSRWNWAEVDNNPFFTPDAGSVEVFADYLDGIRKNGSSVGAIIEIVAEGVPAGIGAPIYGKLDQDIASYLMSINAVKGVEIGNGFEAARLTGEENADEMRMGNDGKPIFLSNHAGGVLGGIATGAPVVARFAVKPTSSILTPRRSIDKDGNEVDVMTRGRHDPCVGIRAVPIGEAMVACAIADHYLRHRGQTGRV
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: BACA_BACSU
Sequence: MIILDNSIQTKKRTDSLSKLITVNTLGPEGTSSEYAAKHFISNFTLLQGLNSKLSLHDTFESCIERTLQSPLEYTIVPHAYDGIKHFYMRPDLQLLQIFRCDTPMYGLAVRPDFEFRDDMLDTSVIVSHPSPINLIKYFTRKDVRFKLVNSTSQAARKVKEGLYDIALTNELARQKYGLTFVKTFKSIPMSWSLFGKGDVDDEN
What is the function of this protein?
Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin.  Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase (PubMed:15609023, PubMed:20052993).  BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate (PubMed:20052993)(PubMed:22483065).  BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1-propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro-hydroxyphenylpyruvate (en-H2HPP) (PubMed:20052993, PubMed:22483065, PubMed:22765234).  En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic-delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP) (PubMed:20052993)(PubMed:22483065).  BacA isomerizes only the pro-R double bond in prephenate (PubMed:22483065).
What are the official names of this protein?
Prephenate decarboxylase, Bacilysin biosynthesis protein BacA, Non-aromatizing prephenate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the prephenate decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA2_HOTTA
Sequence: MHTPKHAIRRMSKGEMEFFEGRCQRMGEAKRTMWGTKWCGSGNEAINYTDLGYFSNLDSCCRTHDHCDSIPAGETKYGLTNEGKYTMMNCKCESAFEKCLRDVRGILEGKAAAAVRKTYFDLYGNGCFNVKCPSGARSARSEECTNGMATYTGETGYGAWAINKLNG
What is the function of this protein?
Phospholipase toxin, which catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.  Inhibits both skeletal (RYR1) and cardiac (RYR2) ryanodine receptors (calcium release channels).  Probably blocks ryanodine receptors by generating a lipid product (By similarity).  Shows hemolytic activity, but it is not know if it is direct or indirect.
What are the official names of this protein?
Phospholipase A2, MtsPLA2.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group III subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NUOC_XANAC
Sequence: MAEQASSFTDRLAARFAGAQIAVALPRGEVTLEVAAADWHATCLALRDELGFEQLSDLCGVDYLGYGSDEWDTADVSSQGFSRGVEGKAVGRFAWGEFPSQESSAGAQPQQLPKQRFAVVAQLISYQHNQRLRVRCYAPDEQVPVVASVTDIWPGVNWFEREAFDLFGIVFDGHPDLRRILTDYGFVGHPFRKDFPLIGNVEVRYDDERKRVVYEPVTSVEPRVGVPRVIRDDARYETAAGEVGKSETAK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ATPD_PELPD
Sequence: MINSTIAKRYALSLVQLGAECGLVDRFRGELADVEDLFGTTPEIPAAFADPALSHERKKNIMRELVGSCACSELMGNFLLLLVDKNRVAFFSQIVKAYGQLADEHVGILRPVITTAFELDAVQLAAIREALEKKSAKTIIPQLTVDKAFLGGVVVQIGDTVYDSSVKTQLKRIQDQLQKG
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RECQ_ECOLI
Sequence: MAQAEVLNLESGAKQVLQETFGYQQFRPGQEEIIDTVLSGRDCLVVMPTGGGKSLCYQIPALLLNGLTVVVSPLISLMKDQVDQLQANGVAAACLNSTQTREQQLEVMTGCRTGQIRLLYIAPERLMLDNFLEHLAHWNPVLLAVDEAHCISQWGHDFRPEYAALGQLRQRFPTLPFMALTATADDTTRQDIVRLLGLNDPLIQISSFDRPNIRYMLMEKFKPLDQLMRYVQEQRGKSGIIYCNSRAKVEDTAARLQSKGISAAAYHAGLENNVRADVQEKFQRDDLQIVVATVAFGMGINKPNVRFVVHFDIPRNIESYYQETGRAGRDGLPAEAMLFYDPADMAWLRRCLEEKPQGQLQDIERHKLNAMGAFAEAQTCRRLVLLNYFGEGRQEPCGNCDICLDPPKQYDGSTDAQIALSTIGRVNQRFGMGYVVEVIRGANNQRIRDYGHDKLKVYGMGRDKSHEHWVSVIRQLIHLGLVTQNIAQHSALQLTEAARPVLRGESSLQLAVPRIVALKPKAMQKSFGGNYDRKLFAKLRKLRKSIADESNVPPYVVFNDATLIEMAEQMPITASEMLSVNGVGMRKLERFGKPFMALIRAHVDGDDEE
What is the function of this protein?
Involved in the RecF recombination pathway; its gene expression is under the regulation of the SOS system.  It is a DNA helicase.
What are the official names of this protein?
ATP-dependent DNA helicase RecQ.
What is the protein family that this protein belongs to?
Belongs to the helicase family. RecQ subfamily.
Protein: SMAD5_RAT
Sequence: MTSMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQPNSTPFPLSPNSPYPPSPASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDNSQPMDTSNNMIPQIMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPANNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS
What is the function of this protein?
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase.  SMAD5 is a receptor-regulated SMAD (R-SMAD) (By similarity).
What are the official names of this protein?
Mothers against decapentaplegic homolog 5, MAD homolog 5, Mothers against DPP homolog 5, SMAD family member 5, SMAD 5, Smad5.
What is the protein family that this protein belongs to?
Belongs to the dwarfin/SMAD family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=In the cytoplasm in the absence of ligand. Migration to the nucleus when complexed with SMAD4 (By similarity).
Protein: HIS7_DEHM1
Sequence: MTKRTASIKRQTTETTISLSLNLDGSGQAEMCTGVRLFDHMLSQLAKHGLFDINVSANGDDIHHLVEDVALTLGKAFNEALGERKGIVRMADATVPMDDSLATVALDLSGRGYAVVDLPFSKNDLTGFPTDLVRHFLETFAIEGRLNLHARILYGSNDHHKAEALFKALARALDKATSLDPRREGIAPSTKGMLEN
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMB_PSEAE
Sequence: MSQWEKVYGVHAVEALLRHHPKRVKQLWLAEGRHDPRVQVLTELAAGFRIPVGQRDRRELDEWAEGVHQGVVAEVSPSQVWGENMLEELLERSEGVPLLLALDGVTDPHNLGACLRTADAAGVQAVIVPKDKSATLNATVRKVACGAAEVIPLVAVTNLARTLEKLQQRGLWVVGTAGEADKTLYQLDLKGPTVLVMGAEGKGMRRLTREHCDFLARLPMAGSVSSLNVSVATGVCLFEILRQRTPLE
What is the function of this protein?
Specifically methylates the ribose of guanosine 2251 in 23S rRNA.
What are the official names of this protein?
23S rRNA (guanosine-2'-O-)-methyltransferase RlmB, 23S rRNA (guanosine2251 2'-O)-methyltransferase, 23S rRNA Gm2251 2'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S35B2_CAEEL
Sequence: MDRSIMPIDSPARDKPPDELVWPLRLFLILLGYSTVATPAAILIYYVRRNRHAFETPYLSIRLLLRSFAVGNPEYQLIPTGEKQARKENDSIPQTRAQCINVIILLLFFFSGIQVTLVAMGVLQERIITRGYRRSDQLEVEDKFGETQFLIFCNRIVALVLSLMILAKDWTKQPPHVPPLYVHSYTSFSNTISSWCQYEALKYVSFPTQTICKASKVVVTMLMGRLVRGQRYSWFEYGCGCTIAFGASLFLLSSSSKGAGSTITYTSFSGMILMAGYLLFDAFTLNWQKALFDTKPKVSKYQMMFGVNFFSAILCAVSLIEQGTLWSSIKFGAEHVDFSRDVFLLSLSGAIGQIFIYSTIERFGPIVFAVIMTIRQMLSIVLSTIMYGHELTFLAAIGFMIVFAAIFVDIHKKYSDKSRGPQRSW
What is the function of this protein?
Mediates the transport of adenosine 3'-phospho 5'-phosphosulfate (PAPS), from cytosol into Golgi.  PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi (By similarity).
What are the official names of this protein?
Adenosine 3'-phospho 5'-phosphosulfate transporter 1, PAPS transporter 1.
What is the protein family that this protein belongs to?
Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: YL334_YEAST
Sequence: MDNLIIAGILLLIKAMIFCIVNILEVLLEDIGILKSLFLHNAITIISSSVLYFLLSYYIINPRISASIIFDDCFSIFMLSSYTVCDDILITRILNKQMMLQFHPIRTIIKLLQHFPVKSSPNAHTA
What are the official names of this protein?
Putative uncharacterized protein YLR334C.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.