PharMolix/UniProtQA huggingface dataset:
Protein: TGT_OCEIH
Sequence: MNPITYELIKTDKQTGARLGRVHTPHGSFDTPTFMPVGTLATVKTMSPEDLQSMQANIILSNTYHLWLRPGEDIIREAGGLHKFMNWDGAILTDSGGFQVFSLSDMREIKEEGVHFRNHLNGEKLFLSPEKAMDIQNALGSDIMMAFDECPPYPAEYDYMKASVERTSRWAERCLQAHNRPHDQGLFGIVQGGEYEALRKQSAEDLVSLDFPGYAIGGLSVGEPKHVMNKVLEFTTPFLPSNKPRYLMGVGSPDALIDGAIRGVDMFDCVLPTRIARNGTCMTSNGRLVVRNAKYARDFNPIDEHCSCHVCKNYSRAYIRHLIKCNETFGFRLTTYHNLHFLLKLMEQVRTAIKEDRLGDFKESFFEQYGLNKANPKNF
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: PO4F1_HUMAN
Sequence: MMSMNSKQPHFAMHPTLPEHKYPSLHSSSEAIRRACLPTPPLQSNLFASLDETLLARAEALAAVDIAVSQGKSHPFKPDATYHTMNSVPCTSTSTVPLAHHHHHHHHHQALEPGDLLDHISSPSLALMAGAGGAGAAAGGGGAHDGPGGGGGPGGGGGPGGGPGGGGGGGPGGGGGGPGGGLLGGSAHPHPHMHSLGHLSHPAAAAAMNMPSGLPHPGLVAAAAHHGAAAAAAAAAAGQVAAASAAAAVVGAAGLASICDSDTDPRELEAFAERFKQRRIKLGVTQADVGSALANLKIPGVGSLSQSTICRFESLTLSHNNMIALKPILQAWLEEAEGAQREKMNKPELFNGGEKKRKRTSIAAPEKRSLEAYFAVQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKRMKFSATY
What is the function of this protein?
Able to act as transcription factor, cannot regulate the expression of the same subset of genes than isoform 1.  Does not have antiapoptotic effect on neuronal cells.
What are the official names of this protein?
POU domain, class 4, transcription factor 1, Brain-specific homeobox/POU domain protein 3A, Brain-3A, Brn-3A, Homeobox/POU domain protein RDC-1, Oct-T1.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-4 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: PYRI_BACFN
Sequence: MSENKQALQVAALKNGTVIDHIPSEKLFTVVSLLGLEHMTTNITIGFNLDSKKLGKKGIIKIADKFFCDEEINRISVVAPHVKLNIIRDYEVVEKKEVRMPDELKAIVKCANPKCITNNEPMATLFHVIDKDNCVIKCHYCEKEQKREDITII
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: GBPA_VIBCM
Sequence: MKKQPKMTAIALILSGISGLAYGHGYVSAVENGVAEGRVTLCKFAANGTGEKNTHCGAIQYEPQSVEGPDGFPVTGPRDGKIASAESALAAALDEQTADRWVKRPIQAGPQTFEWTFTANHVTKDWKYYITKPNWNPNQPLSRDAFDLNPFCVVEGNMVQPPKRVNHECIVPEREGYQVILAVWDVGDTAASFYNVIDVKFDGNGPVLPDWNPAGQIIPSMDLSIGDTVYTRVFDNEGENPAYRTELKIDSETLTKANQWSYALATKINQTQKQQRAGQLNGDQFVPVYGTNPIYLKEGSGLKSVEIGYQIEAPQPEYSLTVSGLAKEYEIGEQPIQLDLTLEAQGEMSAELTVYNHHQKPLASWSQAMTDGELKSVTLELSEAKAGHHMLVSRIKDRDGNLQDQQTLDFMLVEPQTPPTPGDYDFVFPNGLKEYVAGTKVLASDGAIYQCKPWPYSGYCQQWTSNATQYQPGTGSHWEMAWDKH
What is the function of this protein?
Probably interacts with GlcNAc residues.  May promote attachment to both epithelial cell surfaces and chitin.
What are the official names of this protein?
GlcNAc-binding protein A.
What is the protein family that this protein belongs to?
Belongs to the GbpA family.
What are the subcellular locations of this protein?
Secreted.
Protein: ENGB_THEMA
Sequence: MIIRDVELVKVARTPGDYPPPLKGEVAFVGRSNVGKSSLLNALFNRKIAFVSKTPGKTRSINFYLVNSKYYFVDLPGYGYAKVSKKERMLWKRLVEDYFKNRWSLQMVFLLVDGRIPPQDSDLMMVEWMKSLNIPFTIVLTKMDKVKMSERAKKLEEHRKVFSKYGEYTIIPTSSVTGEGISELLDLISTLLKEN
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: TRPC_AZOVD
Sequence: MSLPTVLEKIIARKLEEVAERSARVPLAEVEALARSASAPRGFAEALRAQVESKEPAVIAEVKKASPSKGVLREHFVPAEIAKSYEEGGATCLSVLTDVDFFQGSDAYLQEARAACGLPVIRKDFLIDPYQVVEARALGADCVLLIVAALGDAQMLELAATAKEVGLDVLVEVHDGTELERALQLETPLIGINNRNLHTFEVSLETTLDLLPKVPRERLVVTESGILNRADVELMEVSGVYAFLVGEAFMRAEKPGAELRRLFFPN
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: Y356_METJA
Sequence: MALKEFGGLIMKFLVVKKGSETKRINVEEIKEISNVGSFVIIRYSGGEVKIKAKGDAEEAADWITKMITDFPNKIIDLRAGFESGDKAKTNLRVEAC
What are the official names of this protein?
Uncharacterized protein MJ0356.
Protein: HS906_ARATH
Sequence: MIRLSKRSVSTLLRSGNQSFRIAAAASTSRSSPSATDVKRSDTESRWYSSLTNGQSKNSGSFAQLNMKTNWFMGYRNESSAAASDSSSQAPPPAEKFEYQAEVSRLMDLIVNSLYSNKEVFLRELISNASDALDKLRYLSVTNPELSKDAPDLDIRIYADKENGIITLTDSGIGMTRQELVDCLGTIAQSGTAKFMKALKDSKDAGGDNNLIGQFGVGFYSAFLVADRVIVSTKSPKSDKQYVWEGEANSSSFTIQEDTDPQSLIPRGTRITLHLKQEAKNFADPERIQKLVKNYSQFVSFPIYTWQEKGYTKEVEVEDDPTETKKDDQDDQTEKKKKTKKVVERYWDWELTNETQPIWLRNPKEVTTAEYNEFYRKAFNEYLDPLASSHFTTEGEVEFRSILYVPPVSPSGKDDIVNQKTKNIRLYVKRVFISDDFDGELFPRYLSFVKGVVDSHDLPLNVSREILQESRIVRIMKKRLVRKAFDMILGISLSENREDYEKFWDNFGKHLKLGCIEDRENHKRIAPLLRFFSSQSENDMISLDEYVENMKPEQKAIYFIASDSITSAKNAPFLEKMLEKGLEVLYLVEPIDEVAVQSLKAYKEKDFVDISKEDLDLGDKNEEKEAAVKKEFGQTCDWIKKRLGDKVASVQISNRLSSSPCVLVSGKFGWSANMERLMKAQSTGDTISLDYMKGRRVFEINPDHSIIKNINAAYNSNPNDEDAMRAIDLMYDAALVSSGFTPDNPAELGGKIYEMMDVALSGKWSSPEVQPQQQQMAHSHDAETFEAEVVEPVEVDGKK
What is the function of this protein?
Molecular chaperone which stabilizes unfolding protein intermediates and functions as a folding molecular chaperone that assists the non-covalent folding of proteins in an ATP-dependent manner.
What are the official names of this protein?
Heat shock protein 90-6, mitochondrial, AtHSP90.6, AtHsp90-6, Heat shock protein 89-1, Hsp89-1.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: YTDP_BACSU
Sequence: MGGFMKRSQYKFYYKLITFFCLLSTIPVILVGLFSYEHSQKTAISNVSEEKFDTLQQTQQSIEHILKTVDHSLTHYVSSPPLLRTLSEPLHSDQFQIYNQVNQELNYLQSFDTDLSNMTLVSYTKKWYMNNSGLYRLNTDTLHEAASAYTKQKASRSYWTLEENNHLISTKEGTAENCRYNINLIKQLPLNSTNTKGLAAASIPSCSLVKNMPGYSNANNLFIIDEKGLIILHNNMSDVGESLHNDGFVQKVLAQTANSGQFETVIDRIHYKVTYQKSDYNAWTYFSLVSLPELKKEAKSIGWITFAVCLILLTLSLLFSWLGSRHFYKPIRVLYESFARHGAIQEKQQPPQNEFELIEQSFKQLKDRNDDLEETMKQQATHLQQYFMVRLMLGKLTDEEVDNRFESLGLKQNWRHLALLVLQIDTLNHTPYEKKDMDLLLFAVNSLIERNIPTDKHLAPAVVDKQQATILINQSGTKEEFMAELNETARMIQEKAEAELQLSVSIGISQPFDVLTKAKTAYAEGSEALKYRLKAENKSIIFYEDLDQKKTFKTHFPKQLQHELFDAVKAGDKEKADKCLHAILQAIFTQNTNPYQFQIAIARFLNHVIELMHVLGIELFELEENKMLYDQIFELKTFEDTENWLKNEFIDPMTDKVNARADAQYKNISDNIIHIIHHEFESELTLDEIARRLHYNPNYLSSIFKKEMGISFSEYVSSYRHHMAKSWLAETDMAVKDIAEKLKYKNSQNFIRSFKKLEGITPGNYRQQKRSM
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator YtdP.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MTFA_CROS8
Sequence: MIKWPWKANHTAALAPLPWEAALAIPLLAGLSDEQQQKLVRLSERFLQQKRLVPLQGFELDELKSARIALLFCLPVLELGLEWLDGFHEVLIYPAPFVVDDEWEDDIGLVHNQRVVQSGQSWQQGPIILNWLDIQDSFDASGFNLIIHEVAHKLDMRNGDRASGIPLIALREVAGWEHDLHAAMENIQDEIDLVGESAASIDAYAATDPAECFAVLSEYFFSAPELFAPRFPSLWQRFCHFYGQDPLLRLRLRETPALSDGGQVH
What is the function of this protein?
Involved in the regulation of ptsG expression by binding and inactivating Mlc.
What are the official names of this protein?
Protein MtfA, Mlc titration factor A.
What is the protein family that this protein belongs to?
Belongs to the MtfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBRA_SHIDS
Sequence: MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRYAFDLWMKSLIPASVEVYHDNLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRYLYPDHQIRKYVAIQQWFAEKHPVPFYSCIFDNAITDCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFGKAVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSAEILRSVLLKQPEKINAAYWHATCKLRLKLFGKIVKSRCLTAPALRKWIMRSGMAHIPQLKD
What are the official names of this protein?
Protein CbrA.
What is the protein family that this protein belongs to?
Belongs to the CbrA family.
Protein: ADPPT_XENLA
Sequence: MKLSALKRCVMGSVRWAFQCGSWCPSQAEWLLCARCVQPEEKQRIGHFMFTRDAKAAMAGRLLMRKVIADKLQIPWDRILLERTGKGKPFLTGGSSSEYPCFNFNVSHQGDYAVLAAEPDRQVGVDIMKTDLPGSSSIEEFFRLMNRQFTEKEWNSIRSMNNDWARLDMFYRHWALKESFIKAIGVGLGFNLQRIEFEVSPVTMEIGKIYKETKMFLDDEEETWTFEEILLDNQHHVAIALGEVDHLQHQSPKIGDVAESTFTLLNFEDLMVSAIPMSDEDPDYWINFQSKQELPFRQRRSR
What is the function of this protein?
Catalyzes the post-translational modification of target proteins by phosphopantetheine.  Can transfer the 4'-phosphopantetheine moiety from coenzyme A, regardless of whether the CoA is presented in the free thiol form or as an acetyl thioester, to a serine residue of a broad range of acceptors.
What are the official names of this protein?
L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase, 4'-phosphopantetheinyl transferase, Alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase, AASD-PPT.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RS2_SHEB5
Sequence: MTTVSMRDMLQAGVHFGHQTRYWNPKMKPFIFGARNGVHIINLEHTVPMFNEALAFISNVASKKGKVLFVGTKRAAGEAIKESALSCDQFYVDHRWLGGMLTNWKTVRQSIKRLKELESQSVDGTFDKLTKKEALMRTRELEKLEKSLGGIKNMGGLPDVLFVIGADHEHIAIKEANNLGIPVVAVVDTNSAPDGVNYIVPGNDDAMRAIRLYTSSVAAAAKAGRGQDLAVQAEQDGFVEAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: ACPS_LACPL
Sequence: MIYGTGIDLTELSRIEAILAKGLRLPEKILTPAELAVFSRYPVKRQIEFMAGRFSAKEAYSKAYGTGIGAAVGFQDIEILDNAQGKPEVTRHPFDGPAWISISHTDTLVMTQVILERGNL
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y535_METJA
Sequence: MVSIMPKILYNPEVLGHKPKSYHVENPERVLTILNSLKSNGFDDIVLIEGKSTINEILEIHSRDYVYSIINLSKSFNYYDGDTYLCDRTLDAALTAFKLAKEAVKLALKDRDLYFALTRPPGHHAGISGRALGAMSNGFCIFNNIAGAARLAKNYMKKVIIIDFDVHHGNGTQEIFWNDNRVIHIDFHQRGIYPGTGDILDIGGEEAKGTKINLPFPAHSTDADYIFAWNEIVEPILNYFSPDTVLVSAGFDAFINDGLASMDLTETFYRFVGAKLSGYSVTAVLEGGYSIGLKYAPPAFLDGYVDAKDVLDNLEDYTVINSNEVKSMVKNVKKIIGEYLDIF
What is the function of this protein?
Putative deacetylase.
What are the official names of this protein?
Uncharacterized protein MJ0535.
What is the protein family that this protein belongs to?
Belongs to the histone deacetylase family.
Protein: Y737_METJA
Sequence: MPWWKCSNCGYVFEAEKPPERCPNCGEKCTFYDVSCYTPECGFKGYDPKLVARTPNQESKM
What are the official names of this protein?
Uncharacterized protein MJ0737.
Protein: ATP6A_ARATH
Sequence: MRLFDPWPVFFKREWKRCWPFLTGFAVTGVLITKLTAGLTEEDAKNSKFVQQHRR
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (Probable).  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk (Probable).  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (Probable).  Part of the complex F(0) domain (Probable).  Confers tolerance to several abiotic stresses (e. g.  salt, mannitol, drought, oxidative and cold stresses), probably by providing additional energy needed for cell homeostasis (PubMed:18338219, PubMed:23096681).
What are the official names of this protein?
ATP synthase small subunit 6-A, mitochondrial, AtMtATP6, MtATP6, ATP synthase 6 kDa subunit, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ATPase 6 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: NUOB_HYDS0
Sequence: MASSINGNGFITTTVDELLSWGRRNALWPVTIGLACCAIEMMHAAASRFDIDRLGMIFRASPRQADVLIVAGTVVNKVAPMLKLVWDQMPEPKWCISMGGCASAGGPFPTYSTLQGIDRIIPVDVYIPGCPPTPQGLIYGLLELQRKIREKKVTRYEKAFEEFKKDLSPELLNGVGV
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: VE1_HPV08
Sequence: MADHKGSTSKEGLSEWCILEAECSDVDNDFEQLFERDTDSDISDLLDNCDLDQGNSLELFHQQECEQSEEQLQKLKRKYLSPKAVAQLSPRLQSISLSPQQKSKRRLFAEQDSGVELTLNNEAEDVSHEVEVPAIDSRPEDEGGSGALDIDYTALLRSSNTKATLMAKFKEAFGDGFNELTRQFKSYKTCCNYWVVAAYAVHDVYESSKQLLQQHCDYIWVRSIAAITLYLLSFKAGKNRGTVHKLMTSMLNVQEQQILSEPPKLRHTAAALFWYKGGMGTGTFTYGSYPDWIAHQTILGHQSAEASTFDFSVMVQWAFDNNHFEEADIAYGYAKLAPEDANAVAWLAHNSQAKFVRECAAMVRFYKRGQMREMTMSEWIYTRINEVEGEGHWSSIVKFVRYQGINFITFLAALKDFLHSVPKRNCLLIYGPPNTGKSTFAMSLIQVLKGRVLSYVNSKSQFWLQPLGDCKIALLDDVTDPCWLYMDTFLRNGLDGHVVSLDCKYKAPMQIKFPPLLLTSNINLHEEANYRYLHSRVRGFEFPNPFPMKPDNTPEFELTDQSWKSFFARLWTQLELSDQEDEGEHGESQRAFQCSARSANEHL
What is the function of this protein?
ATP-dependent DNA helicase required for initiation of viral DNA replication.  It forms a complex with the viral E2 protein.  The E1-E2 complex binds to the replication origin which contains binding sites for both proteins.  During the initial step, a dimer of E1 interacts with a dimer of protein E2 leading to a complex that binds the viral origin of replication with high specificity.  Then, a second dimer of E1 displaces the E2 dimer in an ATP-dependent manner to form the E1 tetramer.  Following this, two E1 monomers are added to each half of the site, which results in the formation of two E1 trimers on the viral ori.  Subsequently, two hexamers will be created.  The double hexamer acts as a bi-directional helicase machinery and unwinds the viral DNA and then recruits the host DNA polymerase to start replication.
What are the official names of this protein?
Replication protein E1, ATP-dependent helicase E1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E1 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: RM41_YEAST
Sequence: MPRLTVGTKNMLYPLQKTLAVGSCKPEQVPIRSLASVVESSSKILDKSGSDREVDINVSEKIYKWTKAGIEQGKEHFKVGGNKVYFPKARIILLRPNAKHTPYQAKFIVPKSFNKLDLRDYLYHIYGLRAMNITTQLLHGKFNRMNLQTTRFREPQIKKMTIEMEEPFIWPEEPRPDENSFWDSTTPDNMEKYREERLNCLGSDANKPGTAFDGVVGPYERVAQPFIPRFLKREIDNKRERHAAELQRADKLIALNRYIEDLH
What is the function of this protein?
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain.  The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
What are the official names of this protein?
54S ribosomal protein L41, mitochondrial, Mitochondrial large ribosomal subunit protein uL23m, YmL41.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
What are the subcellular locations of this protein?
Mitochondrion. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1.
Protein: ERAP2_BOVIN
Sequence: MANSCRKLIFNIYVVFYCSAVIMPQICICSQFTSSPIDQFNKDPKAFPVATNGEIFPWHELRLPTVVIPLHYDLLIHPNLTSLDFVASEKIEVLVRDATQFIILHSKDLEILNASLQSEEDVRYKKPGENLTVLSYPAHQQIALLVPEKLRAHLRYSVAIDFQAKLADGFEGFYKSTYRTLGGETRTIAVTDFEPTEARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVRMSTYLVAYIVCDFTSVSGTASSGVKVSIYASPDKWSQTHYALEASVKLLDFYENYFDIHYPLPKLDLVAIPDFASGAMENWGLITYRETSLLFDPKTSSTSDKLWVTKVIAHELAHQWFGNLVTMEWWNDIWLNEGFARYMELISLNITYPELQFDDSFSNTCFEVIKRDSLNSSHPISNEAKTATQIKEMFDAVSYNKGACILNMLKDFLSEETFRKGIIHYLKKFTYRNAKNDDLWHSLSNNCLEGDSTSGGFCYSDSRKTSNTLAFLRENVELKEMMATWTLQKGIPLVVVKREGRSLRLQQERFLSGVFKEDPEWGTLQERYLWHIPVTYSTSSSQAIHRHILKLKTDTVDLSEKTDWVKFNVDSSGYYIVHYEGQGWDELITLLNQNHTLLRPKDRLGLIHDAFQLVSAGRLTLDKALDLTRYLQHETSIPALLKGLEYLELFYRMVERRNISDVTENLKHYLLQYFKPVIDTQSWLDEGSVWDRMLRSTVLKLACYLNHAPCIQKATELFSQWMESSGKLNIPADVLTIVYSVGAQTTAGWNYLLEQYELSLSGAEKNKILYALSTSKHQEKLMKLIELGMEGKVIKTQDLATLLFTTARNPKGQQLAWNFVKENWTHLLKKFELGSFPIRMIISGTTSHFSSKDELQEVKLFFESLKAQGSHLDIFQIILETISKNIKWLEKNLPTLRKWLLTSI
What is the function of this protein?
Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides.  Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules.  Preferentially hydrolyzes the basic residues Arg and Lys (By similarity).
What are the official names of this protein?
Endoplasmic reticulum aminopeptidase 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: ACPS_CHRVO
Sequence: MIYGIGTDLVEIARMEAWCRRWGEKAGRRLLTAAEQAEFAAHAEPARFLAKRFAAKEAFAKALGTGVVAPALLTAIGVGHDELGKPVLILSDELAAFAAARGIARMHLSISDERGHALAFVVLES
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHNN_SHIDS
Sequence: MTGKLIWLMGPSGSGKDSLLAELRLREQTQLLVAHRYITRDASAGSENHIALSEQEFFTRAGQNLLALSWHANGLYYGVGVEIDLWLHAGFDVLVNGSRAHLPQARARYQSALLPICLQVSPEILRQRLENRGRENASEINARLVRAARYTPQDCHTLNNDGSLCQSVDTLLTLIHQKEKHHACL
What is the function of this protein?
Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).
What are the official names of this protein?
Ribose 1,5-bisphosphate phosphokinase PhnN, Ribose 1,5-bisphosphokinase.
What is the protein family that this protein belongs to?
Belongs to the ribose 1,5-bisphosphokinase family.
Protein: ARTP_BACSU
Sequence: MKKWLLLLVAACITFALTACGSSNSGSESGKKKLIMGTSADYKPFEYKEGDNIVGFDVELAKALAKKAGYEIEVQDMDFNSLITALKSKQVDLVLSGMTPTPERKKQVDFSDVYYTANHMIVSKKDSGIQSLKDLKGKTVGVQLGSIQEEKGKELSPEYGFKTEDRNRISDLVQEIKSDRFDAAIIEDIVAEGYFKSNDDLQGFVIPDAKAEEAGSAIAFRKDSELTDKFNKALKEMEDNGELEKLKKKWFTGEK
What is the function of this protein?
Part of a binding-protein-dependent transport system for arginine.
What are the official names of this protein?
Arginine-binding extracellular protein ArtP.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 3 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: RPB4_HUMAN
Sequence: MAAGGSDPRAGDVEEDASQLIFPKEFETAETLLNSEVHMLLEHRKQQNESAEDEQELSEVFMKTLNYTARFSRFKNRETIASVRSLLLQKKLHKFELACLANLCPETAEESKALIPSLEGRFEDEELQQILDDIQTKRSFQY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs.  Pol II is the central component of the basal RNA polymerase II transcription machinery.  It is composed of mobile elements that move relative to each other.  RPB4 is part of a subcomplex with RPB7 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element.  The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft.  The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase II subunit RPB4, RNA polymerase II subunit B4, DNA-directed RNA polymerase II subunit D, RNA polymerase II 16 kDa subunit, RPB16.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HRK_HUMAN
Sequence: MCPCPLHRGRGPPAVCACSAGRLGLRSSAAQLTAARLKALGDELHQRTMWRRRARSRRAPAPGALPTYWPWLCAAAQVAALAAWLLGRRNL
What is the function of this protein?
Promotes apoptosis.
What are the official names of this protein?
Activator of apoptosis harakiri, BH3-interacting domain-containing protein 3, Neuronal death protein DP5.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Mitochondrion.
Protein: RS13_SHEPW
Sequence: MARIAGINIPDQKHTVIALTAIYGIGRTRAQAICAATSIAEDAKIKELSEAQIDTLREEVANYIVEGDLRREVSMNIKRLMDLGCYRGLRHRRSLPLRGQRTKTNARTRKGPRKPIRK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: COWN_RHOPA
Sequence: MSASFDRYVSFQHCDWEGRSERVMQRLQRHVEAAENPFWAYFAQKRAELRDKQGLDDLRILHNYLPTLRELLEDNGDLETLEMLEDLEANLM
What is the function of this protein?
Is required to sustain N(2)-dependent growth in the presence of low levels of carbon monoxide (CO).  Probably acts by protecting the N(2) fixation ability of the nitrogenase complex, which is inactivated in the presence of CO.
What are the official names of this protein?
N(2)-fixation sustaining protein CowN, CO weal-nitrogenase.
What is the protein family that this protein belongs to?
Belongs to the CowN family.