PharMolix/UniProtQA huggingface dataset:
Protein: CYB_PAROL
Sequence: MASLRKSHPLLKIANDALVDLPAPSNISVWWNFGSLLGLCLITQILTGLFLAMHYTSDIATAFTSVAHICRDVNYGWLIRNIHANGASFFFICIYLHIGRGLYYGSFLYKETWNVGVILLLLVMMTAFVGYVLPWGQMSFWGATVITNLLSAVPYVGNTLVQWIWGGFSVDNATLTRFFAFHFLFPFVIAAATVIHLIFLHETGSNNPTGLNSDSDKVPFHPYFSYKDLLGFAALLIALAALALFSPNLLGDPDNFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLFSILILMLVPILHTSKQRSLMFRPFSQFLFWSLVADVMILTWIGGMPVEHPFVIIGQVASFLYFFLFLVMIPVTGWLENKILGWQ
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL33_CALS8
Sequence: MAAKGARMIIHLECTECKNRNYTTEKNKKNDPDRLELRKYCKFCRKHTLHRETK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: NUOI_WOLTR
Sequence: MLKKLAWYWSFVELIKGFIITLRYAFKPKVTLKYPMEKGPLSPRFRGEHALRRYSNGEERCIACKLCEVICPAQAIVIEAEEREDGSRRTTRYDIDMTKCIYCGLCQEACPVDAIVEGPNFEFATETREELMYNKEKLLRNGEIWEEAIALRLKKDVSYH
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL10_EUGGR
Sequence: MGRRPAKCYRYCKNKAYPKSRYCRGVPEAKIRIYDCGMRKLNADTFPLTYHLISMEREQIGSEALEAARINANKYMIKNAGKEAYHIRVRVHPFHVCRINKMLSCAGADRLQQGMRGAFGKPNGLAARVRIGQPLMSIRVKPQHEAVVVAALKRASYKFAGRQVIAKSTMWGFTEIRSENYVKWKEEGKFRVDGVSTKILRNRGRLHRAKRVRAA
What are the official names of this protein?
60S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: SYP_MYCA1
Sequence: MITRMSQLFLRTLRDDPADAEVPSHKLLIRAGYIRPVAPGLYSWLPLGLRVLRRIEHIVREEMNAIGGQEILFPALLPRAPYEATNRWTEYGDSVFRLQDRRGNDYLLGPTHEELFTLTVKGEYSSYKDFPVLLYQIQNKYRDEARPRAGILRVREFVMKDSYSFDIDDAGLKAAYHAHREAYQRIFARLQVRYVIVSAVSGAMGGSASEEFLAESPVGEDTFVRCLESGYAANVEAVITARPDPQPVEGLPEAVVHDTGDTPTIATLVDWANRAGLGRTVTAADTLKNVLLKVRQPGGDWELLAIGLPGDREVDDKRLGAALEPAEYVLLDDADFARYPFLVKGYIGPKALKDNGVRYLVDPRVVDGTSWITGADEPGRHVVGLVAGRDFTADGTIEAAEVRDGDPSPDGAGPLVSARGIEVAHIFQLGRKYTDAFTADVLGEDGKPVRLTMGSYGLGVSRMVAVIAEQHHDELGLRWPASVAPFDVHLVIANKDAQARAGATALADDLDRLGVEVLLDDRQASPGVKFKDAELLGVPWIVVVGRGWADGVVELRDRFAGQTRELATGPSLAADIAAALRG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_ORYSI
Sequence: MARRAASRAVGALRSDGSIQGRGGRAGGSGAEDARHVFDELLRRGRGASIYGLNRALADVARDSPAAAVSRYNRMARAGADEVTPDLCTYGILIGCCCRAGRLDLGFAALGNVIKKGFRVDAIAFTPLLKGLCADKRTSDAMDIVLRRMTELGCIPNVFSYNILLKGLCDENRSQEALELLHMMADDRGGGSPPDVVSYTTVINGFFKEGDSDKAYSTYHEMLDRGILPDVVTYNSIIAALCKAQAMDKAMEVLNTMVKNGVMPDCMTYNSILHGYCSSGQPKEAIGFLKKMRSDGVEPDVVTYSLLMDYLCKNGRCMEARKIFDSMTKRGLKPEITTYGTLLQGYATKGALVEMHGLLDLMVRNGIHPDHYVFSILICAYAKQGKVDQAMLVFSKMRQQGLNPNAVTYGAVIGILCKSGRVEDAMLYFEQMIDEGLSPGNIVYNSLIHGLCTCNKWERAEELILEMLDRGICLNTIFFNSIIDSHCKEGRVIESEKLFELMVRIGVKPNVITYNTLINGYCLAGKMDEAMKLLSGMVSVGLKPNTVTYSTLINGYCKISRMEDALVLFKEMESSGVSPDIITYNIILQGLFQTRRTAAAKELYVRITESGTQIELSTYNIILHGLCKNKLTDDALQMFQNLCLMDLKLEARTFNIMIDALLKVGRNDEAKDLFVAFSSNGLVPNYWTYRLMAENIIGQGLLEELDQLFLSMEDNGCTVDSGMLNFIVRELLQRGEITRAGTYLSMIDEKHFSLEASTASLFIDLLSGGKYQEYYRFLPEKYKSFIESLSC
What is the function of this protein?
Reduces the expression of the cytoplasmic male sterility (CMS)-associated mitochondrial gene ORF79, encoding a cytotoxic peptide.  Can restore male fertility by blocking ORF79 production via endonucleolytic cleavage of dicistronic ATP6/ORF79 mRNA.  Promotes the editing of ATP6 mRNAs independently of its cleavage function.
What are the official names of this protein?
Protein Rf1, mitochondrial, Fertility restorer, Protein PPR, Restorer for CMS.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GUAA_PYRAE
Sequence: MEKVLVVNFGGQYAHLIARRIREVGVYAEIASPEEAVIKASKEEVKAVILSGGPSSVYEPGAPDIDEGIFALSKPVLGICYGHQMIAKKLGGKVERGKGEYGKTIVKILVNDPLFDGWKPEEAVWMSHSDFVEEPPPGFHVLAISENGYIAAMRKGLIYGVQFHPEVHHTSKGRVMFENFLRKIARISDVWRPEDQITRIVEEIRSRVKGGDVIVGVSGGVDSTVTAVLLYKAVGQRVKAVFIDHGLFREGEPEEAASLLKSIGIDVVYIDAKERFLKRLEGVADCEEKRRIIGETFAEVFSDAVKQMPNVKYLAQGTLYPDVVESGAVKGADKIKSHHNVGGLPPWFQLELIEPLREFYKDEVRRIAKALGLPEDVVYRHPFPGPGLAVRIIGPFTREKLAIVRKATKIVEEELRKAGLFRKVWQAFATVGEDKWVGVKGDRRAMGYIVTVRIVESEDAMTADWSRIPFEILEKISSRITSEIPEVTMVTYAVTSKPPSTIEPC
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: DBX1B_DANRE
Sequence: MMLPSVIAPPAMYPSFLRPSSALSLPPALQSAFTTHSSFLVEDLLRISRPAAFMHRSIPSPSASPPATGVTTLNTTSSAVHVAMSTALAKRSSSPQTSISSDPNYLKFGVNAILASTTRNASPPPPVQGMNAKTFPFPCFDGSFHPFIRASYFPASSSAVPIPGTFAWPLTARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLATKLGLKDSQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPTKMNPNPDLSDVGKRFEHEAVLRESPRAPFCQSRGDHEFNADLHFKSPSISSKHSDFSESEDEEITVS
What are the official names of this protein?
Homeobox protein DBX1-B, Developing brain homeobox protein 1-B, Homeobox protein hlx2.
What is the protein family that this protein belongs to?
Belongs to the H2.0 homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CNU_SHIBS
Sequence: MTVQDYLLKFRKISSLESLEKLYDHLNYTLTDDQELINMYRAADHRRAELVSGGRLFDLGQVPKSVWHYVQ
What is the function of this protein?
Modifies the set of genes regulated by H-NS; Hha and cnu (YdgT) increase the number of genes bound by H-NS/StpA and may also modulate the oligomerization of the H-NS/StpA-complex on DNA.  The complex formed with H-NS binds to the specific 26-bp cnb site in the origin of replication oriC.
What are the official names of this protein?
OriC-binding nucleoid-associated protein, H-NS/StpA-binding protein 2, Transcription modulator YdgT.
What is the protein family that this protein belongs to?
Belongs to the Hha/YmoA/Cnu family.
Protein: EFTU_CORGL
Sequence: MAKAKFERTKPHVNIGTIGHVDHGKTTTTAAITKVLADTYPELNEAFAFDSIDKAPEEKERGITINISHVEYQTEKRHYAHVDAPGHADYIKNMITGAAQMDGAILVVAATDGPMPQTREHVLLARQVGVPYILVALNKCDMVEDEEIIELVEMEVRELLAEQDYDEEAPIVHISALKALEGDEKWGKQILELMQACDDNIPDPVRETDKPFLMPIEDIFTITGRGTVVTGRVERGTLNVNDDVDIIGIKEKSTSTTVTGIEMFRKLLDSAEAGDNCGLLLRGIKREDVERGQVIVKPGAYTPHTEFEGSVYVLSKDEGGRHTPFFDNYRPQFYFRTTDVTGVVKLPEGTEMVMPGDNVDMSVTLIQPVAMDEGLRFAIREGSRTVGAGRVTKIIK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_THEP3
Sequence: MRRPIIAGNWKMHMTPSEAVKLVEELIPQVKDAKAEVVVIPPFVDLTEVNKVIQGTNILLGAQDMFWEEKGAYTGEISPLMLKEIGVKYVVIGHSERRQYFGETDEMVNKKVLSALSHGLSPIVCVGESLSQREEGKTFEVVLNQTKEALKGVSHDDIVNVVIAYEPIWAIGTGKTATAKDANEVIKALRNTIASLYGKEKASLVRIQYGGSVKPENISELMAESDIDGALVGGASLVASDFAKIVNY
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_ACIB5
Sequence: MSSIVAIKGFNDVLPTQTAAWRRLEQHLASLMDAYGYQQIRLPIVEQTGLFKRAIGDATDIVEKEMYTFFDKGNPPESLTLRPEGTAGCVRALVEHNLLRGATPRVWYMGPMFRYEKPQKGRYRQFHQFGVETFGVATPDIDAELIMLTARLWKRMGVDHMVQLELNTLGETDERTEYRNALVAFLNEHKDALDEDSQRRLTTNPLRILDSKIESTQKILENAPKLHDFLKEESLSHFQQLQDYLTAAGIKFVINQKLVRGLDYYNKTVFEWTTTALGSQGTVCAGGRYDGLVGQLKGKADQSVPAVGFAMGMERLLLLLEQVEQAEIVRDCEAFLVAEPAYQSKALVLAEQLRDQLEAANSNIRIKTGSQGSMKSQMKKADQAGAVYAIILGEREWEAQQLAVKELATAEQSQVALAELVPFLIEKFTK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA_FUSNN
Sequence: MVFKNSIDLYKKAVELIPGGVNSPVRAFKSVNREAPIFIKKGQGAKIWDEDDNEYIDYICSWGPLILGHNHPKVIEEVKKIIENGSSYGLPTKYEVDLAELIVDIVPSIEKVRLTTSGTEATMSAVRLARAYTQRNKILKFEGCYHGHSDALLVKSGSGLLTEGYQDSNGITDGVLKDTLTLPFGDIEKVKEILKNKDVACVIVEPIPANMGLIETHKEFLQGLGKVTEKTGTILIFDEVISGFRLALGGAQEFFGITPDLTTLGKIIGGGYPVGAFGGKKEIMDLVAPVGRVYHAGTLSGNPIASKAGFATISYLKENPNIYKELEEKTNYLIDNIEILAKKYSVNVCVNSMGSLFTIFFVDIDKVENLEDSLKSNTENFSIYFNTMLENGIVIPPSQFEAHFLSMAHTKKELNRTLEVIEMAFKKIGEKSGK
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYV_STRP3
Sequence: MTELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIPPPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGQGITRYDLGREKFLDKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVFVDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVATTRPETMFGDVAVAVNPEDPRYKDLIGKHVILPIVNKLIPIVGDEHADPEFGTGVVKITPAHDPNDFEVGQRHNLPQVNVMNDDGTMNELAGDFAGMDRFEARQATVAKLEELGALVNIEKRVHSVGHSERSGAVVEPRLSTQWFVKMDELAKQAMDNQETDDRVDFYPPRFNDTFLQWMENVHDWVISRQLWWGHQIPAWYNAEGEIYVGEEAPEGDGWTQDEDVLDTWFSSALWPFSTMGWPDTDVEDFKRYFPTSTLVTGYDIIFFWVSRMIFQTLEFTGRQPFQNVLIHGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADSLRWFLSNGSAPGQDVRFSYEKMDASWNFINKIWNISRYILMNNEGLTLEEAESNVAKVAASEAGNVTDQWILHNLNETIAKVTENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEAEKVITRSVLLYTLDKILRLLHPIMPFVTEEIYAQYAQGSIVTAAYPTVTPAFENEAAHKGVESLKDLIRAVRNARAEVNVAPSKPITILVKTADSELEDFFTSNVNYIKRFTNPEKLEISSAIAAPELAMTSIITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLGNERFVANAKPEVVQKEKDKQADYQAKYDATQERIAEMQKLVK
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVC_ECOBW
Sequence: MAIILGIDPGSRVTGYGVIRQVGRQLSYLGSGCIRTKVDDLPSRLKLIYAGVTEIITQFQPDYFAIEQVFMAKNADSALKLGQARGVAIVAAVNQELPVFEYAARQVKQTVVGIGSAEKSQVQHMVRTLLKLPANPQADAADALAIAITHCHVSQNAMQMSESRLNLARGRLR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: MRH4_CHAGB
Sequence: MWRAARGSVCLLCRSAAQPRTALLESAQPWISQRSFAMRRDATRERPSRMVLSDRVARGPRTDAPRRPRDRPDGPWAGANRTVANVDRDRRRRPPGSTQERDGGTRDRDTRDTRERHPGASRNRDDNRFKALKMQRALTSIAYRERVNVKAQGVYNEVLKGMVGVKPTPVQRLAIPALLGQRIGQQRETNHRRAAPESKREEFLLAAETGSGKTLAYLLPIINALKVAEADDVDAKAYNVRLEAEKERRGGTPVSEWIDKFEPHPNHARPRAIVLVPTSELVDQVLAASKKNFPRGQDQTTAASTWSLPPRIFSPTWRIVTLISSRVCTTSSIDEADSLFDRSFAPETSKIVERAMPSLKQLILCSATIPRRLDNYLAAHFPNIVRIATPNLHAIPRRVQLGVIDVSKDPLPPTTSWLASHHGLCQTSARPPRRWPSTLVSKGIDAIALHRDTPEHRQSEMLNSFTTTEPMRLSKAEVEANKQAALAKAGGVSKRHLANTKVIVATDLASRGIDTLAVRHVVLYDVPHTTIDFIHRLGRAGRMGRRGRGVVLVGKDDRRDVVSEVKESMFMGQALI
What is the function of this protein?
ATP-binding RNA helicase involved in mitochondrial RNA metabolism.  Required for maintenance of mitochondrial DNA (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase MRH4, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. MRH4 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: LUTB1_BACMK
Sequence: MGMKIGNDPFHKRTATGIGDQFMRQAVRKAQDGLRVKKLKATESLGNWEEWRALGEEIRKHTLENLDYYLYELSENIEKNGGFVYFAKTAEDAREYVKEIVKKKNAKKIVKSKSMVTEEISLNEAIEEAGAEVLETDLAEFILQVNDHDPPSHIVVPCLHKDKEHICEIFKTKLNYTGTSDPTEMARFVRSYLRDDFFAADIGVTGCNFAVAESGSISIVANEGNARLTTTLPKTLITVMGMERIVPTWEELDVLVTLLCRSSVGQKLTSYITGLTEPGGTDGPEEFHLVIVDNGRSDIVGTEFQSVLQCIRCAACINVCPVYRHIGGHAYGSIYPGPIGAVLTPLLGGYDEYKDLPYASSLCGACTEACPVKIPLHDLLIKHRSRIVEEKQSPVAWNVAMKGFEKAVKSPRLFSFAAKSAPYALKPLAKGDKIERGIGPLKAWTDARDFPVPKKQPFREWFEKHVKENDDGHSKS
What is the function of this protein?
Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source.  Has probably a role as an electron transporter during oxidation of L-lactate.
What are the official names of this protein?
Lactate utilization protein B 1.
What is the protein family that this protein belongs to?
Belongs to the LutB/YkgF family.
Protein: TRPF_NITHX
Sequence: MSLIVKICGLSTPATLDVTLQGGADMVGFVFFPPSPRHLDLSRARELGAQVRGRAGKVALTVDADDATLGGIIEALRPDLLQLHGKETVARIREIKRTFGLPIMKAIGIETAGDLAALPGYAAVADRVLFDAHPPKDATRPGGLGVPFDWRLLENLAPGIPFMLSGGLTAGNVDAAVRTTRAGGVDVSSGVESAPGVKDAGMIGDFIRAARAAEINLREATSHVG
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: SKEL1_DROME
Sequence: MLAMKDKPWLLLFGLLAALSCLASFGDAAYPYYGTKIGALTRLHHGVSGDVYAVDSRTIFIKKFNYDGEAPAAYFYVGNTARPSNEGAARLRDERGGTASLTRRYRNKDVTLSLPEGKTLRDIKWFSVWCDEFAVNFGDVSIPPNLDFPRPQKISALRGVHGVSSDNIVIVDAQTLLVPNFSYDGEAPDAKFWVGRGQRPTSDGLRIPDENGKENPLRRYERKTIVLTLPEDLTIFDIGHFGVWCEAFTVDFGHVRLPEGLNVPPSLKMLGISPQSKLNCEVLYDDLAFEVRWAVAGESIVVQLVAKLEPNHYMSFGISPNKNISQMIGADAVVAWVDPQTGNGFATDYFLEGKAQCSGGRGACPDTKISEKTNSIRLLNAAMVNGYSIVTYQRSLAATDRLDLPISITGAESVVWAIGPLNDYQEVSFHTFYNKHLHQIEFGRQPKWNCPLPEGARGNSNSSEQEDSAPAAQSSTGGAGYPPAGRPNVEPDEEFYENRAEALHRQPPQRRQETAIITQRRPVPTPKPVNSNGAWDIPAIQCHEPEDGVFYAQMGPTGGKHGYPAITGHVGWGISWYINGLLIPEIHVVRGKTYTFVVEGGNNPDIPAKYHPFYISDDPVGGYEHKREEEKKAVRIYAGVHRSRSGQVTPTGVGRLCNWTPDVEGPPADDYQSFGAYQRTLTLKCDAGEPGVITWKPDRNTPDTVYYHCFTHRYLGWKIHVHDSCDSEAGGLKGAASERHEIRLPAKATVAEPAPVHEDYAGEASVRHETKMASALLRLSRRAY
What is the function of this protein?
Provides structural support to stabilize and organize the microtubule spindle during mitosis (within embryonic somatic cells) and meiosis (within spermatocytes).  The role in mitosis regulation depends on the Ran pathway.
What are the official names of this protein?
Protein Skeletor, isoforms B/C.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, spindle. Nucleus, nucleolus. Chromosome. Note=Part of a macromolecular complex forming the spindle matrix. During mitosis, associated with chromatin at interphase, redistributes to the spindle structure at prophase (preceding the formation of the microtubule spindle) through to anaphase. Extends from one end of the spindle to the other during metaphase and anaphase, coaligns with the microtubule spindle.
Protein: VKT_OXYSC
Sequence: MSSGGLLLLLGLLTLWEVLTPVSSKDRPKFCHLPPKPGPCRAAIPRFYYNPHSKQCEKFIYGGCHGNANSFKTPDECNYTCLGVSLPK
What is the function of this protein?
Monomer: serine protease inhibitor that inhibits plasma kallikrein (Ki=0. 057 nM), tissue kallikrein (Ki=0. 23 nM), trypsin (Ki=0. 31 nM), plasmin (Ki=6. 1 nM), elastase (Ki=201 nM), factor Xa (Ki=871 nM), alpha-factor XIIa (Ki=2380 nM).  Does not inhibit APC, urokinase-type plasminogen activator (uPA/PLAU), tissue plasminogen activator (tPA/PLAT), thrombin and factor VIIa.  In addition, the monomer inhibits fibrinolysis in whole blood and prolonged the intrinsec clotting time.
What are the official names of this protein?
Kunitz-type serine protease inhibitor taicotoxin, Taicatoxin, serine protease inhibitor component, TCX, TSPI, Venom protease inhibitor 1, Venom protease inhibitor 2.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y028_PYRCJ
Sequence: MRIRKPAVAGYFYESRADELQARIEWSIKHEIGPKAPVLPKLGTEALGGVVPHAGYMYSGPVAAWLYSALAGYGAPTTFVIIGPNHYGIGAPVAIMKSGAWETPFGRVEIDEELASLIASNYREIEDDAHAFSKEHSIEVQLPFIQYYFKNVKFVPIAVWRQTLSTSRELGKAIAKALREYKRRVYLLASSDFNHYEPHDVTVKKDDMAIGKILELDEAGLFDVASRFDISICGIGPIASVIVAAKELGFSNAALLKHATSGDTSGYRDETVGYASILFYK
What are the official names of this protein?
MEMO1 family protein Pcal_0028.
What is the protein family that this protein belongs to?
Belongs to the MEMO1 family.
Protein: QOX1_STAAM
Sequence: MNFPWDQLLVKGNWMITMAQIGAPFLVIGLIAVITYFKLWKYLYKEWFTSVDHKKIGIMYLICAVLMFVRGGIDALLIRAQLTVPDNKFLESNHYNEIFSTHGVIMIIFMAMPFIFGLWNIVVPLQIGARDVAFPVLNNVSFWLFFAGMILFNLSFIIGGSPAAGWTNYAPLAGEFSPGPGVNYYLIAIQISGLGTLATGINFFVTILRCKTPTMKFMQMPMFTVTTFITTLIVILAFPPLTVALALMTTDRIFDTAFFTVAHGGMPMLWANFFWVWGHPEVYIVILPAFGIYSEIIPTFARKRLFGHQSMVWATAGIAFLSFLVWVHHFFTMGNGALINSFFSISTMLIGIPTGVKLFNWLLTLYKGRITFESPMLFSLAFIPNFLLGGVTGVMLAMASADYQYHNTYFLVAHFHYTLVTGVVFACLAGLIFWYPKMMGYKLNETLNKWCFWFFMIGFNVCFLPQFILGLDGMPRRLYTYMPSDGWFLLNLISTIGALLMAIGFLFLVVSIVYSHFKSPREATGDNWDGLGRTLEWTTASAIPPKYNFAITPDWNDYDTFVDMKEHGRHYLDNHNYKDIHMPNNTPVGFWIGIFMTIGGFFLIFETVIPALICLFGIFGTMIYRSFQIDHGYHIPAAEVAETEARLREARIKEREAVSHES
What is the function of this protein?
Catalyzes quinol oxidation with the concomitant reduction of oxygen to water.
What are the official names of this protein?
Probable quinol oxidase subunit 1, Quinol oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DEF_LACP7
Sequence: MAKRNIRIMGDSILNKTSKVIEEVTPKIDTLIDDMLDTMYDAGGVGLAAPQVGVLKRLVVIDVSLEGNEPIILINPEIISTDGEQTGDEGCLSLPGKAGIVTRPNYVKVKAYDRHMKPFEVEGEGLLARAFCHEIDHLDGILYVEKVNGEVHEVTSYDEEEEE
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: YTLD_BACSU
Sequence: MRNSKETIDLLHEQYQFKQKKEKWKVHSFQLAIFILFFSGWEISSRQGWIDPLIFSSPSAVWRLLLEKLGDGSLLSHIGVTLFETVLGFLLGTFMGTCLAALLWWSNRLARILDPYLVILNAMPKVALGPILIVALGPSFISIIAMGAIISVIITTIVVYTAFQEVDENYTKVMKTFGAKKWVIFKEVILPASSPAIISTLKVNVGLSWVGVIVGEFLVSKVGLGYMIIYGFQVFNFTLVFLSLLIIAIFATLMYQGVELLEKKWTKGRT
What is the function of this protein?
Part of a binding-protein-dependent transport system.  Probably responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
Uncharacterized ABC transporter permease protein YtlD.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BIOB_XANOP
Sequence: MSVVVRHDWDHKELQALFDLPFPELLHRAASVHRAHFDPAEVQVSTLLSVKTGGCPEDCAYCPQAQRYDTGVTAQKLLETEEVVAKARQAKAAGASRFCMGAAWRSPKERDIPKVAAMIREVKAMGLETCATLGMLDAGQARALKDAGLDYYNHNLDTAPDYYDTIIHTRQYQDRLNTLEHVRDVGLKTCCGGIVGMGETRDHRIGLLLALATLPAHPDSVPINQLVQVPGTPLHGTQQLDPFEFVRMIAVARIAMPKSMVRLSAGREAMSDELQALCFLAGANSIFYGEKLLTTGNPDTERDQTLFQRLGLRPMQITVDAAEHDHPATVHAEITRSAACEHTA
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: HIS8_MYCS2
Sequence: MSADKVTLADLPLRDNLRGKSPYGAPQLQVPVRLNTNENPHPPSKALVDDVAASVREAAAELHRYPDRDAVALRTDLAAYLTAATGVRLGVENLWAANGSNEILQQLLQAFGGPGRTAIGFVPSYSMHPIISDGTQTEWLQASRAEDFGLDIDVAVSAVTERKPDVVFVTSPNNPSGQSVPLDDLRRVLDAMQGGILIVDEAYGEFSSQPSAVALLDDYPAKLVVSRTMSKAFAFAGGRLGYLAAAPAVIDALLLVRLPYHLSVLTQAAARAALRHADDTLGSVKALIAERERVSAELTRMGYRVIPSDANFVLFGAFTDAPATWQRYLDAGVLIRDVGIPGHLRVTIGLAAENDAFLAAGAELAGTELQPSTSPVGAQ
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.